data_9DWU
# 
_entry.id   9DWU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DWU         pdb_00009dwu 10.2210/pdb9dwu/pdb 
WWPDB D_1000288621 ?            ?                   
EMDB  EMD-47265    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-08 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DWU 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'CoREST complex bound to U2AF2' 
_pdbx_database_related.db_id          EMD-47265 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              alani@bu.edu 
_pdbx_contact_author.name_first         Rhoda 
_pdbx_contact_author.name_last          Alani 
_pdbx_contact_author.name_mi            M 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2741-2665 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hicks, C.W.' 1 0000-0002-6040-6227 
'Alani, R.M.' 2 0000-0003-2741-2665 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.12.12.627852 
_citation.pdbx_database_id_PubMed   39713349 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fisher, R.J.'   1  0000-0003-0238-2826 
primary 'Park, K.'       2  ?                   
primary 'Lee, K.'        3  ?                   
primary 'Pinjusic, K.'   4  ?                   
primary 'Vanasse, A.'    5  ?                   
primary 'Ennis, C.S.'    6  ?                   
primary 'Ficcaro, S.'    7  ?                   
primary 'Marto, J.'      8  ?                   
primary 'Stransky, S.'   9  ?                   
primary 'Duke-Cohan, J.' 10 ?                   
primary 'Geethadevi, A.' 11 ?                   
primary 'Raabe, E.'      12 ?                   
primary 'Sidoli, S.'     13 ?                   
primary 'Hicks, C.W.'    14 ?                   
primary 'Keskin, D.B.'   15 ?                   
primary 'Wu, C.J.'       16 ?                   
primary 'Cole, P.A.'     17 0000-0002-0049-8529 
primary 'Alani, R.M.'    18 0000-0003-2741-2665 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Lysine-specific histone demethylase 1A' 74126.781 1 1.-.-.- ? 'UNP residues 171-836' ? 
2 polymer man 'REST corepressor 1'                     7675.833  1 ?       ? 'UNP residues 311-379' ? 
3 polymer man 'Splicing factor U2AF 65 kDa subunit'    8641.860  1 ?       ? ?                      ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2' 
2 'Protein CoREST'                                                                                 
3 'U2 auxiliary factor 65 kDa subunit,hU2AF(65),hU2AF65,U2 snRNP auxiliary factor large subunit'   
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVH
RVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG
AMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQ
ALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTAL
CKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNG
YSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSA
VQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAI
LKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPAT
VHGALLSGLREAGRIADQFLGAMYTL
;
;PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVH
RVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG
AMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQ
ALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTAL
CKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNG
YSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSA
VQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAI
LKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPAT
VHGALLSGLREAGRIADQFLGAMYTL
;
A ? 
2 'polypeptide(L)' no no RKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVI 
RKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVI B ? 
3 'polypeptide(L)' no no SAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRAS 
SAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRAS C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PRO n 
1 2   SER n 
1 3   GLY n 
1 4   VAL n 
1 5   GLU n 
1 6   GLY n 
1 7   ALA n 
1 8   ALA n 
1 9   PHE n 
1 10  GLN n 
1 11  SER n 
1 12  ARG n 
1 13  LEU n 
1 14  PRO n 
1 15  HIS n 
1 16  ASP n 
1 17  ARG n 
1 18  MET n 
1 19  THR n 
1 20  SER n 
1 21  GLN n 
1 22  GLU n 
1 23  ALA n 
1 24  ALA n 
1 25  CYS n 
1 26  PHE n 
1 27  PRO n 
1 28  ASP n 
1 29  ILE n 
1 30  ILE n 
1 31  SER n 
1 32  GLY n 
1 33  PRO n 
1 34  GLN n 
1 35  GLN n 
1 36  THR n 
1 37  GLN n 
1 38  LYS n 
1 39  VAL n 
1 40  PHE n 
1 41  LEU n 
1 42  PHE n 
1 43  ILE n 
1 44  ARG n 
1 45  ASN n 
1 46  ARG n 
1 47  THR n 
1 48  LEU n 
1 49  GLN n 
1 50  LEU n 
1 51  TRP n 
1 52  LEU n 
1 53  ASP n 
1 54  ASN n 
1 55  PRO n 
1 56  LYS n 
1 57  ILE n 
1 58  GLN n 
1 59  LEU n 
1 60  THR n 
1 61  PHE n 
1 62  GLU n 
1 63  ALA n 
1 64  THR n 
1 65  LEU n 
1 66  GLN n 
1 67  GLN n 
1 68  LEU n 
1 69  GLU n 
1 70  ALA n 
1 71  PRO n 
1 72  TYR n 
1 73  ASN n 
1 74  SER n 
1 75  ASP n 
1 76  THR n 
1 77  VAL n 
1 78  LEU n 
1 79  VAL n 
1 80  HIS n 
1 81  ARG n 
1 82  VAL n 
1 83  HIS n 
1 84  SER n 
1 85  TYR n 
1 86  LEU n 
1 87  GLU n 
1 88  ARG n 
1 89  HIS n 
1 90  GLY n 
1 91  LEU n 
1 92  ILE n 
1 93  ASN n 
1 94  PHE n 
1 95  GLY n 
1 96  ILE n 
1 97  TYR n 
1 98  LYS n 
1 99  ARG n 
1 100 ILE n 
1 101 LYS n 
1 102 PRO n 
1 103 LEU n 
1 104 PRO n 
1 105 THR n 
1 106 LYS n 
1 107 LYS n 
1 108 THR n 
1 109 GLY n 
1 110 LYS n 
1 111 VAL n 
1 112 ILE n 
1 113 ILE n 
1 114 ILE n 
1 115 GLY n 
1 116 SER n 
1 117 GLY n 
1 118 VAL n 
1 119 SER n 
1 120 GLY n 
1 121 LEU n 
1 122 ALA n 
1 123 ALA n 
1 124 ALA n 
1 125 ARG n 
1 126 GLN n 
1 127 LEU n 
1 128 GLN n 
1 129 SER n 
1 130 PHE n 
1 131 GLY n 
1 132 MET n 
1 133 ASP n 
1 134 VAL n 
1 135 THR n 
1 136 LEU n 
1 137 LEU n 
1 138 GLU n 
1 139 ALA n 
1 140 ARG n 
1 141 ASP n 
1 142 ARG n 
1 143 VAL n 
1 144 GLY n 
1 145 GLY n 
1 146 ARG n 
1 147 VAL n 
1 148 ALA n 
1 149 THR n 
1 150 PHE n 
1 151 ARG n 
1 152 LYS n 
1 153 GLY n 
1 154 ASN n 
1 155 TYR n 
1 156 VAL n 
1 157 ALA n 
1 158 ASP n 
1 159 LEU n 
1 160 GLY n 
1 161 ALA n 
1 162 MET n 
1 163 VAL n 
1 164 VAL n 
1 165 THR n 
1 166 GLY n 
1 167 LEU n 
1 168 GLY n 
1 169 GLY n 
1 170 ASN n 
1 171 PRO n 
1 172 MET n 
1 173 ALA n 
1 174 VAL n 
1 175 VAL n 
1 176 SER n 
1 177 LYS n 
1 178 GLN n 
1 179 VAL n 
1 180 ASN n 
1 181 MET n 
1 182 GLU n 
1 183 LEU n 
1 184 ALA n 
1 185 LYS n 
1 186 ILE n 
1 187 LYS n 
1 188 GLN n 
1 189 LYS n 
1 190 CYS n 
1 191 PRO n 
1 192 LEU n 
1 193 TYR n 
1 194 GLU n 
1 195 ALA n 
1 196 ASN n 
1 197 GLY n 
1 198 GLN n 
1 199 ALA n 
1 200 VAL n 
1 201 PRO n 
1 202 LYS n 
1 203 GLU n 
1 204 LYS n 
1 205 ASP n 
1 206 GLU n 
1 207 MET n 
1 208 VAL n 
1 209 GLU n 
1 210 GLN n 
1 211 GLU n 
1 212 PHE n 
1 213 ASN n 
1 214 ARG n 
1 215 LEU n 
1 216 LEU n 
1 217 GLU n 
1 218 ALA n 
1 219 THR n 
1 220 SER n 
1 221 TYR n 
1 222 LEU n 
1 223 SER n 
1 224 HIS n 
1 225 GLN n 
1 226 LEU n 
1 227 ASP n 
1 228 PHE n 
1 229 ASN n 
1 230 VAL n 
1 231 LEU n 
1 232 ASN n 
1 233 ASN n 
1 234 LYS n 
1 235 PRO n 
1 236 VAL n 
1 237 SER n 
1 238 LEU n 
1 239 GLY n 
1 240 GLN n 
1 241 ALA n 
1 242 LEU n 
1 243 GLU n 
1 244 VAL n 
1 245 VAL n 
1 246 ILE n 
1 247 GLN n 
1 248 LEU n 
1 249 GLN n 
1 250 GLU n 
1 251 LYS n 
1 252 HIS n 
1 253 VAL n 
1 254 LYS n 
1 255 ASP n 
1 256 GLU n 
1 257 GLN n 
1 258 ILE n 
1 259 GLU n 
1 260 HIS n 
1 261 TRP n 
1 262 LYS n 
1 263 LYS n 
1 264 ILE n 
1 265 VAL n 
1 266 LYS n 
1 267 THR n 
1 268 GLN n 
1 269 GLU n 
1 270 GLU n 
1 271 LEU n 
1 272 LYS n 
1 273 GLU n 
1 274 LEU n 
1 275 LEU n 
1 276 ASN n 
1 277 LYS n 
1 278 MET n 
1 279 VAL n 
1 280 ASN n 
1 281 LEU n 
1 282 LYS n 
1 283 GLU n 
1 284 LYS n 
1 285 ILE n 
1 286 LYS n 
1 287 GLU n 
1 288 LEU n 
1 289 HIS n 
1 290 GLN n 
1 291 GLN n 
1 292 TYR n 
1 293 LYS n 
1 294 GLU n 
1 295 ALA n 
1 296 SER n 
1 297 GLU n 
1 298 VAL n 
1 299 LYS n 
1 300 PRO n 
1 301 PRO n 
1 302 ARG n 
1 303 ASP n 
1 304 ILE n 
1 305 THR n 
1 306 ALA n 
1 307 GLU n 
1 308 PHE n 
1 309 LEU n 
1 310 VAL n 
1 311 LYS n 
1 312 SER n 
1 313 LYS n 
1 314 HIS n 
1 315 ARG n 
1 316 ASP n 
1 317 LEU n 
1 318 THR n 
1 319 ALA n 
1 320 LEU n 
1 321 CYS n 
1 322 LYS n 
1 323 GLU n 
1 324 TYR n 
1 325 ASP n 
1 326 GLU n 
1 327 LEU n 
1 328 ALA n 
1 329 GLU n 
1 330 THR n 
1 331 GLN n 
1 332 GLY n 
1 333 LYS n 
1 334 LEU n 
1 335 GLU n 
1 336 GLU n 
1 337 LYS n 
1 338 LEU n 
1 339 GLN n 
1 340 GLU n 
1 341 LEU n 
1 342 GLU n 
1 343 ALA n 
1 344 ASN n 
1 345 PRO n 
1 346 PRO n 
1 347 SER n 
1 348 ASP n 
1 349 VAL n 
1 350 TYR n 
1 351 LEU n 
1 352 SER n 
1 353 SER n 
1 354 ARG n 
1 355 ASP n 
1 356 ARG n 
1 357 GLN n 
1 358 ILE n 
1 359 LEU n 
1 360 ASP n 
1 361 TRP n 
1 362 HIS n 
1 363 PHE n 
1 364 ALA n 
1 365 ASN n 
1 366 LEU n 
1 367 GLU n 
1 368 PHE n 
1 369 ALA n 
1 370 ASN n 
1 371 ALA n 
1 372 THR n 
1 373 PRO n 
1 374 LEU n 
1 375 SER n 
1 376 THR n 
1 377 LEU n 
1 378 SER n 
1 379 LEU n 
1 380 LYS n 
1 381 HIS n 
1 382 TRP n 
1 383 ASP n 
1 384 GLN n 
1 385 ASP n 
1 386 ASP n 
1 387 ASP n 
1 388 PHE n 
1 389 GLU n 
1 390 PHE n 
1 391 THR n 
1 392 GLY n 
1 393 SER n 
1 394 HIS n 
1 395 LEU n 
1 396 THR n 
1 397 VAL n 
1 398 ARG n 
1 399 ASN n 
1 400 GLY n 
1 401 TYR n 
1 402 SER n 
1 403 CYS n 
1 404 VAL n 
1 405 PRO n 
1 406 VAL n 
1 407 ALA n 
1 408 LEU n 
1 409 ALA n 
1 410 GLU n 
1 411 GLY n 
1 412 LEU n 
1 413 ASP n 
1 414 ILE n 
1 415 LYS n 
1 416 LEU n 
1 417 ASN n 
1 418 THR n 
1 419 ALA n 
1 420 VAL n 
1 421 ARG n 
1 422 GLN n 
1 423 VAL n 
1 424 ARG n 
1 425 TYR n 
1 426 THR n 
1 427 ALA n 
1 428 SER n 
1 429 GLY n 
1 430 CYS n 
1 431 GLU n 
1 432 VAL n 
1 433 ILE n 
1 434 ALA n 
1 435 VAL n 
1 436 ASN n 
1 437 THR n 
1 438 ARG n 
1 439 SER n 
1 440 THR n 
1 441 SER n 
1 442 GLN n 
1 443 THR n 
1 444 PHE n 
1 445 ILE n 
1 446 TYR n 
1 447 LYS n 
1 448 CYS n 
1 449 ASP n 
1 450 ALA n 
1 451 VAL n 
1 452 LEU n 
1 453 CYS n 
1 454 THR n 
1 455 LEU n 
1 456 PRO n 
1 457 LEU n 
1 458 GLY n 
1 459 VAL n 
1 460 LEU n 
1 461 LYS n 
1 462 GLN n 
1 463 GLN n 
1 464 PRO n 
1 465 PRO n 
1 466 ALA n 
1 467 VAL n 
1 468 GLN n 
1 469 PHE n 
1 470 VAL n 
1 471 PRO n 
1 472 PRO n 
1 473 LEU n 
1 474 PRO n 
1 475 GLU n 
1 476 TRP n 
1 477 LYS n 
1 478 THR n 
1 479 SER n 
1 480 ALA n 
1 481 VAL n 
1 482 GLN n 
1 483 ARG n 
1 484 MET n 
1 485 GLY n 
1 486 PHE n 
1 487 GLY n 
1 488 ASN n 
1 489 LEU n 
1 490 ASN n 
1 491 LYS n 
1 492 VAL n 
1 493 VAL n 
1 494 LEU n 
1 495 CYS n 
1 496 PHE n 
1 497 ASP n 
1 498 ARG n 
1 499 VAL n 
1 500 PHE n 
1 501 TRP n 
1 502 ASP n 
1 503 PRO n 
1 504 SER n 
1 505 VAL n 
1 506 ASN n 
1 507 LEU n 
1 508 PHE n 
1 509 GLY n 
1 510 HIS n 
1 511 VAL n 
1 512 GLY n 
1 513 SER n 
1 514 THR n 
1 515 THR n 
1 516 ALA n 
1 517 SER n 
1 518 ARG n 
1 519 GLY n 
1 520 GLU n 
1 521 LEU n 
1 522 PHE n 
1 523 LEU n 
1 524 PHE n 
1 525 TRP n 
1 526 ASN n 
1 527 LEU n 
1 528 TYR n 
1 529 LYS n 
1 530 ALA n 
1 531 PRO n 
1 532 ILE n 
1 533 LEU n 
1 534 LEU n 
1 535 ALA n 
1 536 LEU n 
1 537 VAL n 
1 538 ALA n 
1 539 GLY n 
1 540 GLU n 
1 541 ALA n 
1 542 ALA n 
1 543 GLY n 
1 544 ILE n 
1 545 MET n 
1 546 GLU n 
1 547 ASN n 
1 548 ILE n 
1 549 SER n 
1 550 ASP n 
1 551 ASP n 
1 552 VAL n 
1 553 ILE n 
1 554 VAL n 
1 555 GLY n 
1 556 ARG n 
1 557 CYS n 
1 558 LEU n 
1 559 ALA n 
1 560 ILE n 
1 561 LEU n 
1 562 LYS n 
1 563 GLY n 
1 564 ILE n 
1 565 PHE n 
1 566 GLY n 
1 567 SER n 
1 568 SER n 
1 569 ALA n 
1 570 VAL n 
1 571 PRO n 
1 572 GLN n 
1 573 PRO n 
1 574 LYS n 
1 575 GLU n 
1 576 THR n 
1 577 VAL n 
1 578 VAL n 
1 579 SER n 
1 580 ARG n 
1 581 TRP n 
1 582 ARG n 
1 583 ALA n 
1 584 ASP n 
1 585 PRO n 
1 586 TRP n 
1 587 ALA n 
1 588 ARG n 
1 589 GLY n 
1 590 SER n 
1 591 TYR n 
1 592 SER n 
1 593 TYR n 
1 594 VAL n 
1 595 ALA n 
1 596 ALA n 
1 597 GLY n 
1 598 SER n 
1 599 SER n 
1 600 GLY n 
1 601 ASN n 
1 602 ASP n 
1 603 TYR n 
1 604 ASP n 
1 605 LEU n 
1 606 MET n 
1 607 ALA n 
1 608 GLN n 
1 609 PRO n 
1 610 ILE n 
1 611 THR n 
1 612 PRO n 
1 613 GLY n 
1 614 PRO n 
1 615 SER n 
1 616 ILE n 
1 617 PRO n 
1 618 GLY n 
1 619 ALA n 
1 620 PRO n 
1 621 GLN n 
1 622 PRO n 
1 623 ILE n 
1 624 PRO n 
1 625 ARG n 
1 626 LEU n 
1 627 PHE n 
1 628 PHE n 
1 629 ALA n 
1 630 GLY n 
1 631 GLU n 
1 632 HIS n 
1 633 THR n 
1 634 ILE n 
1 635 ARG n 
1 636 ASN n 
1 637 TYR n 
1 638 PRO n 
1 639 ALA n 
1 640 THR n 
1 641 VAL n 
1 642 HIS n 
1 643 GLY n 
1 644 ALA n 
1 645 LEU n 
1 646 LEU n 
1 647 SER n 
1 648 GLY n 
1 649 LEU n 
1 650 ARG n 
1 651 GLU n 
1 652 ALA n 
1 653 GLY n 
1 654 ARG n 
1 655 ILE n 
1 656 ALA n 
1 657 ASP n 
1 658 GLN n 
1 659 PHE n 
1 660 LEU n 
1 661 GLY n 
1 662 ALA n 
1 663 MET n 
1 664 TYR n 
1 665 THR n 
1 666 LEU n 
2 1   ARG n 
2 2   LYS n 
2 3   PRO n 
2 4   PRO n 
2 5   LYS n 
2 6   GLY n 
2 7   MET n 
2 8   PHE n 
2 9   LEU n 
2 10  SER n 
2 11  GLN n 
2 12  GLU n 
2 13  ASP n 
2 14  VAL n 
2 15  GLU n 
2 16  ALA n 
2 17  VAL n 
2 18  SER n 
2 19  ALA n 
2 20  ASN n 
2 21  ALA n 
2 22  THR n 
2 23  ALA n 
2 24  ALA n 
2 25  THR n 
2 26  THR n 
2 27  VAL n 
2 28  LEU n 
2 29  ARG n 
2 30  GLN n 
2 31  LEU n 
2 32  ASP n 
2 33  MET n 
2 34  GLU n 
2 35  LEU n 
2 36  VAL n 
2 37  SER n 
2 38  VAL n 
2 39  LYS n 
2 40  ARG n 
2 41  GLN n 
2 42  ILE n 
2 43  GLN n 
2 44  ASN n 
2 45  ILE n 
2 46  LYS n 
2 47  GLN n 
2 48  THR n 
2 49  ASN n 
2 50  SER n 
2 51  ALA n 
2 52  LEU n 
2 53  LYS n 
2 54  GLU n 
2 55  LYS n 
2 56  LEU n 
2 57  ASP n 
2 58  GLY n 
2 59  GLY n 
2 60  ILE n 
2 61  GLU n 
2 62  PRO n 
2 63  TYR n 
2 64  ARG n 
2 65  LEU n 
2 66  PRO n 
2 67  GLU n 
2 68  VAL n 
2 69  ILE n 
3 1   SER n 
3 2   ALA n 
3 3   HIS n 
3 4   LYS n 
3 5   LEU n 
3 6   PHE n 
3 7   ILE n 
3 8   GLY n 
3 9   GLY n 
3 10  LEU n 
3 11  PRO n 
3 12  ASN n 
3 13  TYR n 
3 14  LEU n 
3 15  ASN n 
3 16  ASP n 
3 17  ASP n 
3 18  GLN n 
3 19  VAL n 
3 20  LYS n 
3 21  GLU n 
3 22  LEU n 
3 23  LEU n 
3 24  THR n 
3 25  SER n 
3 26  PHE n 
3 27  GLY n 
3 28  PRO n 
3 29  LEU n 
3 30  LYS n 
3 31  ALA n 
3 32  PHE n 
3 33  ASN n 
3 34  LEU n 
3 35  VAL n 
3 36  LYS n 
3 37  ASP n 
3 38  SER n 
3 39  ALA n 
3 40  THR n 
3 41  GLY n 
3 42  LEU n 
3 43  SER n 
3 44  LYS n 
3 45  GLY n 
3 46  TYR n 
3 47  ALA n 
3 48  PHE n 
3 49  CYS n 
3 50  GLU n 
3 51  TYR n 
3 52  VAL n 
3 53  ASP n 
3 54  ILE n 
3 55  ASN n 
3 56  VAL n 
3 57  THR n 
3 58  ASP n 
3 59  GLN n 
3 60  ALA n 
3 61  ILE n 
3 62  ALA n 
3 63  GLY n 
3 64  LEU n 
3 65  ASN n 
3 66  GLY n 
3 67  MET n 
3 68  GLN n 
3 69  LEU n 
3 70  GLY n 
3 71  ASP n 
3 72  LYS n 
3 73  LYS n 
3 74  LEU n 
3 75  LEU n 
3 76  VAL n 
3 77  GLN n 
3 78  ARG n 
3 79  ALA n 
3 80  SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 666 human ? 'KDM1A, AOF2, KDM1, KIAA0601, LSD1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293F ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 69  human ? 'RCOR1, KIAA0071, RCOR'             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293F ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 80  human ? 'U2AF2, U2AF65'                     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293F ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PRO 1   171 171 PRO PRO A . n 
A 1 2   SER 2   172 172 SER SER A . n 
A 1 3   GLY 3   173 173 GLY GLY A . n 
A 1 4   VAL 4   174 174 VAL VAL A . n 
A 1 5   GLU 5   175 175 GLU GLU A . n 
A 1 6   GLY 6   176 176 GLY GLY A . n 
A 1 7   ALA 7   177 177 ALA ALA A . n 
A 1 8   ALA 8   178 178 ALA ALA A . n 
A 1 9   PHE 9   179 179 PHE PHE A . n 
A 1 10  GLN 10  180 180 GLN GLN A . n 
A 1 11  SER 11  181 181 SER SER A . n 
A 1 12  ARG 12  182 182 ARG ARG A . n 
A 1 13  LEU 13  183 183 LEU LEU A . n 
A 1 14  PRO 14  184 184 PRO PRO A . n 
A 1 15  HIS 15  185 185 HIS HIS A . n 
A 1 16  ASP 16  186 186 ASP ASP A . n 
A 1 17  ARG 17  187 187 ARG ARG A . n 
A 1 18  MET 18  188 188 MET MET A . n 
A 1 19  THR 19  189 189 THR THR A . n 
A 1 20  SER 20  190 190 SER SER A . n 
A 1 21  GLN 21  191 191 GLN GLN A . n 
A 1 22  GLU 22  192 192 GLU GLU A . n 
A 1 23  ALA 23  193 193 ALA ALA A . n 
A 1 24  ALA 24  194 194 ALA ALA A . n 
A 1 25  CYS 25  195 195 CYS CYS A . n 
A 1 26  PHE 26  196 196 PHE PHE A . n 
A 1 27  PRO 27  197 197 PRO PRO A . n 
A 1 28  ASP 28  198 198 ASP ASP A . n 
A 1 29  ILE 29  199 199 ILE ILE A . n 
A 1 30  ILE 30  200 200 ILE ILE A . n 
A 1 31  SER 31  201 201 SER SER A . n 
A 1 32  GLY 32  202 202 GLY GLY A . n 
A 1 33  PRO 33  203 203 PRO PRO A . n 
A 1 34  GLN 34  204 204 GLN GLN A . n 
A 1 35  GLN 35  205 205 GLN GLN A . n 
A 1 36  THR 36  206 206 THR THR A . n 
A 1 37  GLN 37  207 207 GLN GLN A . n 
A 1 38  LYS 38  208 208 LYS LYS A . n 
A 1 39  VAL 39  209 209 VAL VAL A . n 
A 1 40  PHE 40  210 210 PHE PHE A . n 
A 1 41  LEU 41  211 211 LEU LEU A . n 
A 1 42  PHE 42  212 212 PHE PHE A . n 
A 1 43  ILE 43  213 213 ILE ILE A . n 
A 1 44  ARG 44  214 214 ARG ARG A . n 
A 1 45  ASN 45  215 215 ASN ASN A . n 
A 1 46  ARG 46  216 216 ARG ARG A . n 
A 1 47  THR 47  217 217 THR THR A . n 
A 1 48  LEU 48  218 218 LEU LEU A . n 
A 1 49  GLN 49  219 219 GLN GLN A . n 
A 1 50  LEU 50  220 220 LEU LEU A . n 
A 1 51  TRP 51  221 221 TRP TRP A . n 
A 1 52  LEU 52  222 222 LEU LEU A . n 
A 1 53  ASP 53  223 223 ASP ASP A . n 
A 1 54  ASN 54  224 224 ASN ASN A . n 
A 1 55  PRO 55  225 225 PRO PRO A . n 
A 1 56  LYS 56  226 226 LYS LYS A . n 
A 1 57  ILE 57  227 227 ILE ILE A . n 
A 1 58  GLN 58  228 228 GLN GLN A . n 
A 1 59  LEU 59  229 229 LEU LEU A . n 
A 1 60  THR 60  230 230 THR THR A . n 
A 1 61  PHE 61  231 231 PHE PHE A . n 
A 1 62  GLU 62  232 232 GLU GLU A . n 
A 1 63  ALA 63  233 233 ALA ALA A . n 
A 1 64  THR 64  234 234 THR THR A . n 
A 1 65  LEU 65  235 235 LEU LEU A . n 
A 1 66  GLN 66  236 236 GLN GLN A . n 
A 1 67  GLN 67  237 237 GLN GLN A . n 
A 1 68  LEU 68  238 238 LEU LEU A . n 
A 1 69  GLU 69  239 239 GLU GLU A . n 
A 1 70  ALA 70  240 240 ALA ALA A . n 
A 1 71  PRO 71  241 241 PRO PRO A . n 
A 1 72  TYR 72  242 242 TYR TYR A . n 
A 1 73  ASN 73  243 243 ASN ASN A . n 
A 1 74  SER 74  244 244 SER SER A . n 
A 1 75  ASP 75  245 245 ASP ASP A . n 
A 1 76  THR 76  246 246 THR THR A . n 
A 1 77  VAL 77  247 247 VAL VAL A . n 
A 1 78  LEU 78  248 248 LEU LEU A . n 
A 1 79  VAL 79  249 249 VAL VAL A . n 
A 1 80  HIS 80  250 250 HIS HIS A . n 
A 1 81  ARG 81  251 251 ARG ARG A . n 
A 1 82  VAL 82  252 252 VAL VAL A . n 
A 1 83  HIS 83  253 253 HIS HIS A . n 
A 1 84  SER 84  254 254 SER SER A . n 
A 1 85  TYR 85  255 255 TYR TYR A . n 
A 1 86  LEU 86  256 256 LEU LEU A . n 
A 1 87  GLU 87  257 257 GLU GLU A . n 
A 1 88  ARG 88  258 258 ARG ARG A . n 
A 1 89  HIS 89  259 259 HIS HIS A . n 
A 1 90  GLY 90  260 260 GLY GLY A . n 
A 1 91  LEU 91  261 261 LEU LEU A . n 
A 1 92  ILE 92  262 262 ILE ILE A . n 
A 1 93  ASN 93  263 263 ASN ASN A . n 
A 1 94  PHE 94  264 264 PHE PHE A . n 
A 1 95  GLY 95  265 265 GLY GLY A . n 
A 1 96  ILE 96  266 266 ILE ILE A . n 
A 1 97  TYR 97  267 267 TYR TYR A . n 
A 1 98  LYS 98  268 268 LYS LYS A . n 
A 1 99  ARG 99  269 269 ARG ARG A . n 
A 1 100 ILE 100 270 270 ILE ILE A . n 
A 1 101 LYS 101 271 271 LYS LYS A . n 
A 1 102 PRO 102 272 272 PRO PRO A . n 
A 1 103 LEU 103 273 273 LEU LEU A . n 
A 1 104 PRO 104 274 274 PRO PRO A . n 
A 1 105 THR 105 275 275 THR THR A . n 
A 1 106 LYS 106 276 276 LYS LYS A . n 
A 1 107 LYS 107 277 277 LYS LYS A . n 
A 1 108 THR 108 278 278 THR THR A . n 
A 1 109 GLY 109 279 279 GLY GLY A . n 
A 1 110 LYS 110 280 280 LYS LYS A . n 
A 1 111 VAL 111 281 281 VAL VAL A . n 
A 1 112 ILE 112 282 282 ILE ILE A . n 
A 1 113 ILE 113 283 283 ILE ILE A . n 
A 1 114 ILE 114 284 284 ILE ILE A . n 
A 1 115 GLY 115 285 285 GLY GLY A . n 
A 1 116 SER 116 286 286 SER SER A . n 
A 1 117 GLY 117 287 287 GLY GLY A . n 
A 1 118 VAL 118 288 288 VAL VAL A . n 
A 1 119 SER 119 289 289 SER SER A . n 
A 1 120 GLY 120 290 290 GLY GLY A . n 
A 1 121 LEU 121 291 291 LEU LEU A . n 
A 1 122 ALA 122 292 292 ALA ALA A . n 
A 1 123 ALA 123 293 293 ALA ALA A . n 
A 1 124 ALA 124 294 294 ALA ALA A . n 
A 1 125 ARG 125 295 295 ARG ARG A . n 
A 1 126 GLN 126 296 296 GLN GLN A . n 
A 1 127 LEU 127 297 297 LEU LEU A . n 
A 1 128 GLN 128 298 298 GLN GLN A . n 
A 1 129 SER 129 299 299 SER SER A . n 
A 1 130 PHE 130 300 300 PHE PHE A . n 
A 1 131 GLY 131 301 301 GLY GLY A . n 
A 1 132 MET 132 302 302 MET MET A . n 
A 1 133 ASP 133 303 303 ASP ASP A . n 
A 1 134 VAL 134 304 304 VAL VAL A . n 
A 1 135 THR 135 305 305 THR THR A . n 
A 1 136 LEU 136 306 306 LEU LEU A . n 
A 1 137 LEU 137 307 307 LEU LEU A . n 
A 1 138 GLU 138 308 308 GLU GLU A . n 
A 1 139 ALA 139 309 309 ALA ALA A . n 
A 1 140 ARG 140 310 310 ARG ARG A . n 
A 1 141 ASP 141 311 311 ASP ASP A . n 
A 1 142 ARG 142 312 312 ARG ARG A . n 
A 1 143 VAL 143 313 313 VAL VAL A . n 
A 1 144 GLY 144 314 314 GLY GLY A . n 
A 1 145 GLY 145 315 315 GLY GLY A . n 
A 1 146 ARG 146 316 316 ARG ARG A . n 
A 1 147 VAL 147 317 317 VAL VAL A . n 
A 1 148 ALA 148 318 318 ALA ALA A . n 
A 1 149 THR 149 319 319 THR THR A . n 
A 1 150 PHE 150 320 320 PHE PHE A . n 
A 1 151 ARG 151 321 321 ARG ARG A . n 
A 1 152 LYS 152 322 322 LYS LYS A . n 
A 1 153 GLY 153 323 323 GLY GLY A . n 
A 1 154 ASN 154 324 324 ASN ASN A . n 
A 1 155 TYR 155 325 325 TYR TYR A . n 
A 1 156 VAL 156 326 326 VAL VAL A . n 
A 1 157 ALA 157 327 327 ALA ALA A . n 
A 1 158 ASP 158 328 328 ASP ASP A . n 
A 1 159 LEU 159 329 329 LEU LEU A . n 
A 1 160 GLY 160 330 330 GLY GLY A . n 
A 1 161 ALA 161 331 331 ALA ALA A . n 
A 1 162 MET 162 332 332 MET MET A . n 
A 1 163 VAL 163 333 333 VAL VAL A . n 
A 1 164 VAL 164 334 334 VAL VAL A . n 
A 1 165 THR 165 335 335 THR THR A . n 
A 1 166 GLY 166 336 336 GLY GLY A . n 
A 1 167 LEU 167 337 337 LEU LEU A . n 
A 1 168 GLY 168 338 338 GLY GLY A . n 
A 1 169 GLY 169 339 339 GLY GLY A . n 
A 1 170 ASN 170 340 340 ASN ASN A . n 
A 1 171 PRO 171 341 341 PRO PRO A . n 
A 1 172 MET 172 342 342 MET MET A . n 
A 1 173 ALA 173 343 343 ALA ALA A . n 
A 1 174 VAL 174 344 344 VAL VAL A . n 
A 1 175 VAL 175 345 345 VAL VAL A . n 
A 1 176 SER 176 346 346 SER SER A . n 
A 1 177 LYS 177 347 347 LYS LYS A . n 
A 1 178 GLN 178 348 348 GLN GLN A . n 
A 1 179 VAL 179 349 349 VAL VAL A . n 
A 1 180 ASN 180 350 350 ASN ASN A . n 
A 1 181 MET 181 351 351 MET MET A . n 
A 1 182 GLU 182 352 352 GLU GLU A . n 
A 1 183 LEU 183 353 353 LEU LEU A . n 
A 1 184 ALA 184 354 354 ALA ALA A . n 
A 1 185 LYS 185 355 355 LYS LYS A . n 
A 1 186 ILE 186 356 356 ILE ILE A . n 
A 1 187 LYS 187 357 357 LYS LYS A . n 
A 1 188 GLN 188 358 358 GLN GLN A . n 
A 1 189 LYS 189 359 359 LYS LYS A . n 
A 1 190 CYS 190 360 360 CYS CYS A . n 
A 1 191 PRO 191 361 361 PRO PRO A . n 
A 1 192 LEU 192 362 362 LEU LEU A . n 
A 1 193 TYR 193 363 363 TYR TYR A . n 
A 1 194 GLU 194 364 364 GLU GLU A . n 
A 1 195 ALA 195 365 365 ALA ALA A . n 
A 1 196 ASN 196 366 366 ASN ASN A . n 
A 1 197 GLY 197 367 367 GLY GLY A . n 
A 1 198 GLN 198 368 368 GLN GLN A . n 
A 1 199 ALA 199 369 369 ALA ALA A . n 
A 1 200 VAL 200 370 370 VAL VAL A . n 
A 1 201 PRO 201 371 371 PRO PRO A . n 
A 1 202 LYS 202 372 372 LYS LYS A . n 
A 1 203 GLU 203 373 373 GLU GLU A . n 
A 1 204 LYS 204 374 374 LYS LYS A . n 
A 1 205 ASP 205 375 375 ASP ASP A . n 
A 1 206 GLU 206 376 376 GLU GLU A . n 
A 1 207 MET 207 377 377 MET MET A . n 
A 1 208 VAL 208 378 378 VAL VAL A . n 
A 1 209 GLU 209 379 379 GLU GLU A . n 
A 1 210 GLN 210 380 380 GLN GLN A . n 
A 1 211 GLU 211 381 381 GLU GLU A . n 
A 1 212 PHE 212 382 382 PHE PHE A . n 
A 1 213 ASN 213 383 383 ASN ASN A . n 
A 1 214 ARG 214 384 384 ARG ARG A . n 
A 1 215 LEU 215 385 385 LEU LEU A . n 
A 1 216 LEU 216 386 386 LEU LEU A . n 
A 1 217 GLU 217 387 387 GLU GLU A . n 
A 1 218 ALA 218 388 388 ALA ALA A . n 
A 1 219 THR 219 389 389 THR THR A . n 
A 1 220 SER 220 390 390 SER SER A . n 
A 1 221 TYR 221 391 391 TYR TYR A . n 
A 1 222 LEU 222 392 392 LEU LEU A . n 
A 1 223 SER 223 393 393 SER SER A . n 
A 1 224 HIS 224 394 394 HIS HIS A . n 
A 1 225 GLN 225 395 395 GLN GLN A . n 
A 1 226 LEU 226 396 396 LEU LEU A . n 
A 1 227 ASP 227 397 397 ASP ASP A . n 
A 1 228 PHE 228 398 398 PHE PHE A . n 
A 1 229 ASN 229 399 399 ASN ASN A . n 
A 1 230 VAL 230 400 400 VAL VAL A . n 
A 1 231 LEU 231 401 401 LEU LEU A . n 
A 1 232 ASN 232 402 402 ASN ASN A . n 
A 1 233 ASN 233 403 403 ASN ASN A . n 
A 1 234 LYS 234 404 404 LYS LYS A . n 
A 1 235 PRO 235 405 405 PRO PRO A . n 
A 1 236 VAL 236 406 406 VAL VAL A . n 
A 1 237 SER 237 407 407 SER SER A . n 
A 1 238 LEU 238 408 408 LEU LEU A . n 
A 1 239 GLY 239 409 409 GLY GLY A . n 
A 1 240 GLN 240 410 410 GLN GLN A . n 
A 1 241 ALA 241 411 411 ALA ALA A . n 
A 1 242 LEU 242 412 412 LEU LEU A . n 
A 1 243 GLU 243 413 413 GLU GLU A . n 
A 1 244 VAL 244 414 414 VAL VAL A . n 
A 1 245 VAL 245 415 415 VAL VAL A . n 
A 1 246 ILE 246 416 416 ILE ILE A . n 
A 1 247 GLN 247 417 417 GLN GLN A . n 
A 1 248 LEU 248 418 418 LEU LEU A . n 
A 1 249 GLN 249 419 419 GLN GLN A . n 
A 1 250 GLU 250 420 420 GLU GLU A . n 
A 1 251 LYS 251 421 421 LYS LYS A . n 
A 1 252 HIS 252 422 422 HIS HIS A . n 
A 1 253 VAL 253 423 423 VAL VAL A . n 
A 1 254 LYS 254 424 424 LYS LYS A . n 
A 1 255 ASP 255 425 425 ASP ASP A . n 
A 1 256 GLU 256 426 426 GLU GLU A . n 
A 1 257 GLN 257 427 427 GLN GLN A . n 
A 1 258 ILE 258 428 428 ILE ILE A . n 
A 1 259 GLU 259 429 429 GLU GLU A . n 
A 1 260 HIS 260 430 430 HIS HIS A . n 
A 1 261 TRP 261 431 431 TRP TRP A . n 
A 1 262 LYS 262 432 432 LYS LYS A . n 
A 1 263 LYS 263 433 433 LYS LYS A . n 
A 1 264 ILE 264 434 434 ILE ILE A . n 
A 1 265 VAL 265 435 435 VAL VAL A . n 
A 1 266 LYS 266 436 436 LYS LYS A . n 
A 1 267 THR 267 437 437 THR THR A . n 
A 1 268 GLN 268 438 438 GLN GLN A . n 
A 1 269 GLU 269 439 439 GLU GLU A . n 
A 1 270 GLU 270 440 440 GLU GLU A . n 
A 1 271 LEU 271 441 441 LEU LEU A . n 
A 1 272 LYS 272 442 442 LYS LYS A . n 
A 1 273 GLU 273 443 443 GLU GLU A . n 
A 1 274 LEU 274 444 444 LEU LEU A . n 
A 1 275 LEU 275 445 445 LEU LEU A . n 
A 1 276 ASN 276 446 446 ASN ASN A . n 
A 1 277 LYS 277 447 447 LYS LYS A . n 
A 1 278 MET 278 448 448 MET MET A . n 
A 1 279 VAL 279 449 449 VAL VAL A . n 
A 1 280 ASN 280 450 450 ASN ASN A . n 
A 1 281 LEU 281 451 451 LEU LEU A . n 
A 1 282 LYS 282 452 452 LYS LYS A . n 
A 1 283 GLU 283 453 453 GLU GLU A . n 
A 1 284 LYS 284 454 454 LYS LYS A . n 
A 1 285 ILE 285 455 455 ILE ILE A . n 
A 1 286 LYS 286 456 456 LYS LYS A . n 
A 1 287 GLU 287 457 457 GLU GLU A . n 
A 1 288 LEU 288 458 458 LEU LEU A . n 
A 1 289 HIS 289 459 459 HIS HIS A . n 
A 1 290 GLN 290 460 460 GLN GLN A . n 
A 1 291 GLN 291 461 461 GLN GLN A . n 
A 1 292 TYR 292 462 462 TYR TYR A . n 
A 1 293 LYS 293 463 463 LYS LYS A . n 
A 1 294 GLU 294 464 464 GLU GLU A . n 
A 1 295 ALA 295 465 465 ALA ALA A . n 
A 1 296 SER 296 466 466 SER SER A . n 
A 1 297 GLU 297 467 467 GLU GLU A . n 
A 1 298 VAL 298 468 468 VAL VAL A . n 
A 1 299 LYS 299 469 469 LYS LYS A . n 
A 1 300 PRO 300 470 470 PRO PRO A . n 
A 1 301 PRO 301 471 471 PRO PRO A . n 
A 1 302 ARG 302 472 472 ARG ARG A . n 
A 1 303 ASP 303 473 473 ASP ASP A . n 
A 1 304 ILE 304 474 474 ILE ILE A . n 
A 1 305 THR 305 475 475 THR THR A . n 
A 1 306 ALA 306 476 476 ALA ALA A . n 
A 1 307 GLU 307 477 477 GLU GLU A . n 
A 1 308 PHE 308 478 478 PHE PHE A . n 
A 1 309 LEU 309 479 479 LEU LEU A . n 
A 1 310 VAL 310 480 480 VAL VAL A . n 
A 1 311 LYS 311 481 481 LYS LYS A . n 
A 1 312 SER 312 482 482 SER SER A . n 
A 1 313 LYS 313 483 483 LYS LYS A . n 
A 1 314 HIS 314 484 484 HIS HIS A . n 
A 1 315 ARG 315 485 485 ARG ARG A . n 
A 1 316 ASP 316 486 486 ASP ASP A . n 
A 1 317 LEU 317 487 487 LEU LEU A . n 
A 1 318 THR 318 488 488 THR THR A . n 
A 1 319 ALA 319 489 489 ALA ALA A . n 
A 1 320 LEU 320 490 490 LEU LEU A . n 
A 1 321 CYS 321 491 491 CYS CYS A . n 
A 1 322 LYS 322 492 492 LYS LYS A . n 
A 1 323 GLU 323 493 493 GLU GLU A . n 
A 1 324 TYR 324 494 494 TYR TYR A . n 
A 1 325 ASP 325 495 495 ASP ASP A . n 
A 1 326 GLU 326 496 496 GLU GLU A . n 
A 1 327 LEU 327 497 497 LEU LEU A . n 
A 1 328 ALA 328 498 498 ALA ALA A . n 
A 1 329 GLU 329 499 499 GLU GLU A . n 
A 1 330 THR 330 500 500 THR THR A . n 
A 1 331 GLN 331 501 501 GLN GLN A . n 
A 1 332 GLY 332 502 502 GLY GLY A . n 
A 1 333 LYS 333 503 503 LYS LYS A . n 
A 1 334 LEU 334 504 504 LEU LEU A . n 
A 1 335 GLU 335 505 505 GLU GLU A . n 
A 1 336 GLU 336 506 506 GLU GLU A . n 
A 1 337 LYS 337 507 507 LYS LYS A . n 
A 1 338 LEU 338 508 508 LEU LEU A . n 
A 1 339 GLN 339 509 509 GLN GLN A . n 
A 1 340 GLU 340 510 510 GLU GLU A . n 
A 1 341 LEU 341 511 511 LEU LEU A . n 
A 1 342 GLU 342 512 512 GLU GLU A . n 
A 1 343 ALA 343 513 513 ALA ALA A . n 
A 1 344 ASN 344 514 514 ASN ASN A . n 
A 1 345 PRO 345 515 515 PRO PRO A . n 
A 1 346 PRO 346 516 516 PRO PRO A . n 
A 1 347 SER 347 517 517 SER SER A . n 
A 1 348 ASP 348 518 518 ASP ASP A . n 
A 1 349 VAL 349 519 519 VAL VAL A . n 
A 1 350 TYR 350 520 520 TYR TYR A . n 
A 1 351 LEU 351 521 521 LEU LEU A . n 
A 1 352 SER 352 522 522 SER SER A . n 
A 1 353 SER 353 523 523 SER SER A . n 
A 1 354 ARG 354 524 524 ARG ARG A . n 
A 1 355 ASP 355 525 525 ASP ASP A . n 
A 1 356 ARG 356 526 526 ARG ARG A . n 
A 1 357 GLN 357 527 527 GLN GLN A . n 
A 1 358 ILE 358 528 528 ILE ILE A . n 
A 1 359 LEU 359 529 529 LEU LEU A . n 
A 1 360 ASP 360 530 530 ASP ASP A . n 
A 1 361 TRP 361 531 531 TRP TRP A . n 
A 1 362 HIS 362 532 532 HIS HIS A . n 
A 1 363 PHE 363 533 533 PHE PHE A . n 
A 1 364 ALA 364 534 534 ALA ALA A . n 
A 1 365 ASN 365 535 535 ASN ASN A . n 
A 1 366 LEU 366 536 536 LEU LEU A . n 
A 1 367 GLU 367 537 537 GLU GLU A . n 
A 1 368 PHE 368 538 538 PHE PHE A . n 
A 1 369 ALA 369 539 539 ALA ALA A . n 
A 1 370 ASN 370 540 540 ASN ASN A . n 
A 1 371 ALA 371 541 541 ALA ALA A . n 
A 1 372 THR 372 542 542 THR THR A . n 
A 1 373 PRO 373 543 543 PRO PRO A . n 
A 1 374 LEU 374 544 544 LEU LEU A . n 
A 1 375 SER 375 545 545 SER SER A . n 
A 1 376 THR 376 546 546 THR THR A . n 
A 1 377 LEU 377 547 547 LEU LEU A . n 
A 1 378 SER 378 548 548 SER SER A . n 
A 1 379 LEU 379 549 549 LEU LEU A . n 
A 1 380 LYS 380 550 550 LYS LYS A . n 
A 1 381 HIS 381 551 551 HIS HIS A . n 
A 1 382 TRP 382 552 552 TRP TRP A . n 
A 1 383 ASP 383 553 553 ASP ASP A . n 
A 1 384 GLN 384 554 554 GLN GLN A . n 
A 1 385 ASP 385 555 555 ASP ASP A . n 
A 1 386 ASP 386 556 556 ASP ASP A . n 
A 1 387 ASP 387 557 557 ASP ASP A . n 
A 1 388 PHE 388 558 558 PHE PHE A . n 
A 1 389 GLU 389 559 559 GLU GLU A . n 
A 1 390 PHE 390 560 560 PHE PHE A . n 
A 1 391 THR 391 561 561 THR THR A . n 
A 1 392 GLY 392 562 562 GLY GLY A . n 
A 1 393 SER 393 563 563 SER SER A . n 
A 1 394 HIS 394 564 564 HIS HIS A . n 
A 1 395 LEU 395 565 565 LEU LEU A . n 
A 1 396 THR 396 566 566 THR THR A . n 
A 1 397 VAL 397 567 567 VAL VAL A . n 
A 1 398 ARG 398 568 568 ARG ARG A . n 
A 1 399 ASN 399 569 569 ASN ASN A . n 
A 1 400 GLY 400 570 570 GLY GLY A . n 
A 1 401 TYR 401 571 571 TYR TYR A . n 
A 1 402 SER 402 572 572 SER SER A . n 
A 1 403 CYS 403 573 573 CYS CYS A . n 
A 1 404 VAL 404 574 574 VAL VAL A . n 
A 1 405 PRO 405 575 575 PRO PRO A . n 
A 1 406 VAL 406 576 576 VAL VAL A . n 
A 1 407 ALA 407 577 577 ALA ALA A . n 
A 1 408 LEU 408 578 578 LEU LEU A . n 
A 1 409 ALA 409 579 579 ALA ALA A . n 
A 1 410 GLU 410 580 580 GLU GLU A . n 
A 1 411 GLY 411 581 581 GLY GLY A . n 
A 1 412 LEU 412 582 582 LEU LEU A . n 
A 1 413 ASP 413 583 583 ASP ASP A . n 
A 1 414 ILE 414 584 584 ILE ILE A . n 
A 1 415 LYS 415 585 585 LYS LYS A . n 
A 1 416 LEU 416 586 586 LEU LEU A . n 
A 1 417 ASN 417 587 587 ASN ASN A . n 
A 1 418 THR 418 588 588 THR THR A . n 
A 1 419 ALA 419 589 589 ALA ALA A . n 
A 1 420 VAL 420 590 590 VAL VAL A . n 
A 1 421 ARG 421 591 591 ARG ARG A . n 
A 1 422 GLN 422 592 592 GLN GLN A . n 
A 1 423 VAL 423 593 593 VAL VAL A . n 
A 1 424 ARG 424 594 594 ARG ARG A . n 
A 1 425 TYR 425 595 595 TYR TYR A . n 
A 1 426 THR 426 596 596 THR THR A . n 
A 1 427 ALA 427 597 597 ALA ALA A . n 
A 1 428 SER 428 598 598 SER SER A . n 
A 1 429 GLY 429 599 599 GLY GLY A . n 
A 1 430 CYS 430 600 600 CYS CYS A . n 
A 1 431 GLU 431 601 601 GLU GLU A . n 
A 1 432 VAL 432 602 602 VAL VAL A . n 
A 1 433 ILE 433 603 603 ILE ILE A . n 
A 1 434 ALA 434 604 604 ALA ALA A . n 
A 1 435 VAL 435 605 605 VAL VAL A . n 
A 1 436 ASN 436 606 606 ASN ASN A . n 
A 1 437 THR 437 607 607 THR THR A . n 
A 1 438 ARG 438 608 608 ARG ARG A . n 
A 1 439 SER 439 609 609 SER SER A . n 
A 1 440 THR 440 610 610 THR THR A . n 
A 1 441 SER 441 611 611 SER SER A . n 
A 1 442 GLN 442 612 612 GLN GLN A . n 
A 1 443 THR 443 613 613 THR THR A . n 
A 1 444 PHE 444 614 614 PHE PHE A . n 
A 1 445 ILE 445 615 615 ILE ILE A . n 
A 1 446 TYR 446 616 616 TYR TYR A . n 
A 1 447 LYS 447 617 617 LYS LYS A . n 
A 1 448 CYS 448 618 618 CYS CYS A . n 
A 1 449 ASP 449 619 619 ASP ASP A . n 
A 1 450 ALA 450 620 620 ALA ALA A . n 
A 1 451 VAL 451 621 621 VAL VAL A . n 
A 1 452 LEU 452 622 622 LEU LEU A . n 
A 1 453 CYS 453 623 623 CYS CYS A . n 
A 1 454 THR 454 624 624 THR THR A . n 
A 1 455 LEU 455 625 625 LEU LEU A . n 
A 1 456 PRO 456 626 626 PRO PRO A . n 
A 1 457 LEU 457 627 627 LEU LEU A . n 
A 1 458 GLY 458 628 628 GLY GLY A . n 
A 1 459 VAL 459 629 629 VAL VAL A . n 
A 1 460 LEU 460 630 630 LEU LEU A . n 
A 1 461 LYS 461 631 631 LYS LYS A . n 
A 1 462 GLN 462 632 632 GLN GLN A . n 
A 1 463 GLN 463 633 633 GLN GLN A . n 
A 1 464 PRO 464 634 634 PRO PRO A . n 
A 1 465 PRO 465 635 635 PRO PRO A . n 
A 1 466 ALA 466 636 636 ALA ALA A . n 
A 1 467 VAL 467 637 637 VAL VAL A . n 
A 1 468 GLN 468 638 638 GLN GLN A . n 
A 1 469 PHE 469 639 639 PHE PHE A . n 
A 1 470 VAL 470 640 640 VAL VAL A . n 
A 1 471 PRO 471 641 641 PRO PRO A . n 
A 1 472 PRO 472 642 642 PRO PRO A . n 
A 1 473 LEU 473 643 643 LEU LEU A . n 
A 1 474 PRO 474 644 644 PRO PRO A . n 
A 1 475 GLU 475 645 645 GLU GLU A . n 
A 1 476 TRP 476 646 646 TRP TRP A . n 
A 1 477 LYS 477 647 647 LYS LYS A . n 
A 1 478 THR 478 648 648 THR THR A . n 
A 1 479 SER 479 649 649 SER SER A . n 
A 1 480 ALA 480 650 650 ALA ALA A . n 
A 1 481 VAL 481 651 651 VAL VAL A . n 
A 1 482 GLN 482 652 652 GLN GLN A . n 
A 1 483 ARG 483 653 653 ARG ARG A . n 
A 1 484 MET 484 654 654 MET MET A . n 
A 1 485 GLY 485 655 655 GLY GLY A . n 
A 1 486 PHE 486 656 656 PHE PHE A . n 
A 1 487 GLY 487 657 657 GLY GLY A . n 
A 1 488 ASN 488 658 658 ASN ASN A . n 
A 1 489 LEU 489 659 659 LEU LEU A . n 
A 1 490 ASN 490 660 660 ASN ASN A . n 
A 1 491 LYS 491 661 661 LYS LYS A . n 
A 1 492 VAL 492 662 662 VAL VAL A . n 
A 1 493 VAL 493 663 663 VAL VAL A . n 
A 1 494 LEU 494 664 664 LEU LEU A . n 
A 1 495 CYS 495 665 665 CYS CYS A . n 
A 1 496 PHE 496 666 666 PHE PHE A . n 
A 1 497 ASP 497 667 667 ASP ASP A . n 
A 1 498 ARG 498 668 668 ARG ARG A . n 
A 1 499 VAL 499 669 669 VAL VAL A . n 
A 1 500 PHE 500 670 670 PHE PHE A . n 
A 1 501 TRP 501 671 671 TRP TRP A . n 
A 1 502 ASP 502 672 672 ASP ASP A . n 
A 1 503 PRO 503 673 673 PRO PRO A . n 
A 1 504 SER 504 674 674 SER SER A . n 
A 1 505 VAL 505 675 675 VAL VAL A . n 
A 1 506 ASN 506 676 676 ASN ASN A . n 
A 1 507 LEU 507 677 677 LEU LEU A . n 
A 1 508 PHE 508 678 678 PHE PHE A . n 
A 1 509 GLY 509 679 679 GLY GLY A . n 
A 1 510 HIS 510 680 680 HIS HIS A . n 
A 1 511 VAL 511 681 681 VAL VAL A . n 
A 1 512 GLY 512 682 682 GLY GLY A . n 
A 1 513 SER 513 683 683 SER SER A . n 
A 1 514 THR 514 684 684 THR THR A . n 
A 1 515 THR 515 685 685 THR THR A . n 
A 1 516 ALA 516 686 686 ALA ALA A . n 
A 1 517 SER 517 687 687 SER SER A . n 
A 1 518 ARG 518 688 688 ARG ARG A . n 
A 1 519 GLY 519 689 689 GLY GLY A . n 
A 1 520 GLU 520 690 690 GLU GLU A . n 
A 1 521 LEU 521 691 691 LEU LEU A . n 
A 1 522 PHE 522 692 692 PHE PHE A . n 
A 1 523 LEU 523 693 693 LEU LEU A . n 
A 1 524 PHE 524 694 694 PHE PHE A . n 
A 1 525 TRP 525 695 695 TRP TRP A . n 
A 1 526 ASN 526 696 696 ASN ASN A . n 
A 1 527 LEU 527 697 697 LEU LEU A . n 
A 1 528 TYR 528 698 698 TYR TYR A . n 
A 1 529 LYS 529 699 699 LYS LYS A . n 
A 1 530 ALA 530 700 700 ALA ALA A . n 
A 1 531 PRO 531 701 701 PRO PRO A . n 
A 1 532 ILE 532 702 702 ILE ILE A . n 
A 1 533 LEU 533 703 703 LEU LEU A . n 
A 1 534 LEU 534 704 704 LEU LEU A . n 
A 1 535 ALA 535 705 705 ALA ALA A . n 
A 1 536 LEU 536 706 706 LEU LEU A . n 
A 1 537 VAL 537 707 707 VAL VAL A . n 
A 1 538 ALA 538 708 708 ALA ALA A . n 
A 1 539 GLY 539 709 709 GLY GLY A . n 
A 1 540 GLU 540 710 710 GLU GLU A . n 
A 1 541 ALA 541 711 711 ALA ALA A . n 
A 1 542 ALA 542 712 712 ALA ALA A . n 
A 1 543 GLY 543 713 713 GLY GLY A . n 
A 1 544 ILE 544 714 714 ILE ILE A . n 
A 1 545 MET 545 715 715 MET MET A . n 
A 1 546 GLU 546 716 716 GLU GLU A . n 
A 1 547 ASN 547 717 717 ASN ASN A . n 
A 1 548 ILE 548 718 718 ILE ILE A . n 
A 1 549 SER 549 719 719 SER SER A . n 
A 1 550 ASP 550 720 720 ASP ASP A . n 
A 1 551 ASP 551 721 721 ASP ASP A . n 
A 1 552 VAL 552 722 722 VAL VAL A . n 
A 1 553 ILE 553 723 723 ILE ILE A . n 
A 1 554 VAL 554 724 724 VAL VAL A . n 
A 1 555 GLY 555 725 725 GLY GLY A . n 
A 1 556 ARG 556 726 726 ARG ARG A . n 
A 1 557 CYS 557 727 727 CYS CYS A . n 
A 1 558 LEU 558 728 728 LEU LEU A . n 
A 1 559 ALA 559 729 729 ALA ALA A . n 
A 1 560 ILE 560 730 730 ILE ILE A . n 
A 1 561 LEU 561 731 731 LEU LEU A . n 
A 1 562 LYS 562 732 732 LYS LYS A . n 
A 1 563 GLY 563 733 733 GLY GLY A . n 
A 1 564 ILE 564 734 734 ILE ILE A . n 
A 1 565 PHE 565 735 735 PHE PHE A . n 
A 1 566 GLY 566 736 736 GLY GLY A . n 
A 1 567 SER 567 737 737 SER SER A . n 
A 1 568 SER 568 738 738 SER SER A . n 
A 1 569 ALA 569 739 739 ALA ALA A . n 
A 1 570 VAL 570 740 740 VAL VAL A . n 
A 1 571 PRO 571 741 741 PRO PRO A . n 
A 1 572 GLN 572 742 742 GLN GLN A . n 
A 1 573 PRO 573 743 743 PRO PRO A . n 
A 1 574 LYS 574 744 744 LYS LYS A . n 
A 1 575 GLU 575 745 745 GLU GLU A . n 
A 1 576 THR 576 746 746 THR THR A . n 
A 1 577 VAL 577 747 747 VAL VAL A . n 
A 1 578 VAL 578 748 748 VAL VAL A . n 
A 1 579 SER 579 749 749 SER SER A . n 
A 1 580 ARG 580 750 750 ARG ARG A . n 
A 1 581 TRP 581 751 751 TRP TRP A . n 
A 1 582 ARG 582 752 752 ARG ARG A . n 
A 1 583 ALA 583 753 753 ALA ALA A . n 
A 1 584 ASP 584 754 754 ASP ASP A . n 
A 1 585 PRO 585 755 755 PRO PRO A . n 
A 1 586 TRP 586 756 756 TRP TRP A . n 
A 1 587 ALA 587 757 757 ALA ALA A . n 
A 1 588 ARG 588 758 758 ARG ARG A . n 
A 1 589 GLY 589 759 759 GLY GLY A . n 
A 1 590 SER 590 760 760 SER SER A . n 
A 1 591 TYR 591 761 761 TYR TYR A . n 
A 1 592 SER 592 762 762 SER SER A . n 
A 1 593 TYR 593 763 763 TYR TYR A . n 
A 1 594 VAL 594 764 764 VAL VAL A . n 
A 1 595 ALA 595 765 765 ALA ALA A . n 
A 1 596 ALA 596 766 766 ALA ALA A . n 
A 1 597 GLY 597 767 767 GLY GLY A . n 
A 1 598 SER 598 768 768 SER SER A . n 
A 1 599 SER 599 769 769 SER SER A . n 
A 1 600 GLY 600 770 770 GLY GLY A . n 
A 1 601 ASN 601 771 771 ASN ASN A . n 
A 1 602 ASP 602 772 772 ASP ASP A . n 
A 1 603 TYR 603 773 773 TYR TYR A . n 
A 1 604 ASP 604 774 774 ASP ASP A . n 
A 1 605 LEU 605 775 775 LEU LEU A . n 
A 1 606 MET 606 776 776 MET MET A . n 
A 1 607 ALA 607 777 777 ALA ALA A . n 
A 1 608 GLN 608 778 778 GLN GLN A . n 
A 1 609 PRO 609 779 779 PRO PRO A . n 
A 1 610 ILE 610 780 780 ILE ILE A . n 
A 1 611 THR 611 781 781 THR THR A . n 
A 1 612 PRO 612 782 782 PRO PRO A . n 
A 1 613 GLY 613 783 783 GLY GLY A . n 
A 1 614 PRO 614 784 784 PRO PRO A . n 
A 1 615 SER 615 785 785 SER SER A . n 
A 1 616 ILE 616 786 786 ILE ILE A . n 
A 1 617 PRO 617 787 787 PRO PRO A . n 
A 1 618 GLY 618 788 788 GLY GLY A . n 
A 1 619 ALA 619 789 789 ALA ALA A . n 
A 1 620 PRO 620 790 790 PRO PRO A . n 
A 1 621 GLN 621 791 791 GLN GLN A . n 
A 1 622 PRO 622 792 792 PRO PRO A . n 
A 1 623 ILE 623 793 793 ILE ILE A . n 
A 1 624 PRO 624 794 794 PRO PRO A . n 
A 1 625 ARG 625 795 795 ARG ARG A . n 
A 1 626 LEU 626 796 796 LEU LEU A . n 
A 1 627 PHE 627 797 797 PHE PHE A . n 
A 1 628 PHE 628 798 798 PHE PHE A . n 
A 1 629 ALA 629 799 799 ALA ALA A . n 
A 1 630 GLY 630 800 800 GLY GLY A . n 
A 1 631 GLU 631 801 801 GLU GLU A . n 
A 1 632 HIS 632 802 802 HIS HIS A . n 
A 1 633 THR 633 803 803 THR THR A . n 
A 1 634 ILE 634 804 804 ILE ILE A . n 
A 1 635 ARG 635 805 805 ARG ARG A . n 
A 1 636 ASN 636 806 806 ASN ASN A . n 
A 1 637 TYR 637 807 807 TYR TYR A . n 
A 1 638 PRO 638 808 808 PRO PRO A . n 
A 1 639 ALA 639 809 809 ALA ALA A . n 
A 1 640 THR 640 810 810 THR THR A . n 
A 1 641 VAL 641 811 811 VAL VAL A . n 
A 1 642 HIS 642 812 812 HIS HIS A . n 
A 1 643 GLY 643 813 813 GLY GLY A . n 
A 1 644 ALA 644 814 814 ALA ALA A . n 
A 1 645 LEU 645 815 815 LEU LEU A . n 
A 1 646 LEU 646 816 816 LEU LEU A . n 
A 1 647 SER 647 817 817 SER SER A . n 
A 1 648 GLY 648 818 818 GLY GLY A . n 
A 1 649 LEU 649 819 819 LEU LEU A . n 
A 1 650 ARG 650 820 820 ARG ARG A . n 
A 1 651 GLU 651 821 821 GLU GLU A . n 
A 1 652 ALA 652 822 822 ALA ALA A . n 
A 1 653 GLY 653 823 823 GLY GLY A . n 
A 1 654 ARG 654 824 824 ARG ARG A . n 
A 1 655 ILE 655 825 825 ILE ILE A . n 
A 1 656 ALA 656 826 826 ALA ALA A . n 
A 1 657 ASP 657 827 827 ASP ASP A . n 
A 1 658 GLN 658 828 828 GLN GLN A . n 
A 1 659 PHE 659 829 829 PHE PHE A . n 
A 1 660 LEU 660 830 830 LEU LEU A . n 
A 1 661 GLY 661 831 831 GLY GLY A . n 
A 1 662 ALA 662 832 832 ALA ALA A . n 
A 1 663 MET 663 833 833 MET MET A . n 
A 1 664 TYR 664 834 834 TYR TYR A . n 
A 1 665 THR 665 835 835 THR THR A . n 
A 1 666 LEU 666 836 836 LEU LEU A . n 
B 2 1   ARG 1   308 308 ARG ARG B . n 
B 2 2   LYS 2   309 309 LYS LYS B . n 
B 2 3   PRO 3   310 310 PRO PRO B . n 
B 2 4   PRO 4   311 311 PRO PRO B . n 
B 2 5   LYS 5   312 312 LYS LYS B . n 
B 2 6   GLY 6   313 313 GLY GLY B . n 
B 2 7   MET 7   314 314 MET MET B . n 
B 2 8   PHE 8   315 315 PHE PHE B . n 
B 2 9   LEU 9   316 316 LEU LEU B . n 
B 2 10  SER 10  317 317 SER SER B . n 
B 2 11  GLN 11  318 318 GLN GLN B . n 
B 2 12  GLU 12  319 319 GLU GLU B . n 
B 2 13  ASP 13  320 320 ASP ASP B . n 
B 2 14  VAL 14  321 321 VAL VAL B . n 
B 2 15  GLU 15  322 322 GLU GLU B . n 
B 2 16  ALA 16  323 323 ALA ALA B . n 
B 2 17  VAL 17  324 324 VAL VAL B . n 
B 2 18  SER 18  325 325 SER SER B . n 
B 2 19  ALA 19  326 326 ALA ALA B . n 
B 2 20  ASN 20  327 327 ASN ASN B . n 
B 2 21  ALA 21  328 328 ALA ALA B . n 
B 2 22  THR 22  329 329 THR THR B . n 
B 2 23  ALA 23  330 330 ALA ALA B . n 
B 2 24  ALA 24  331 331 ALA ALA B . n 
B 2 25  THR 25  332 332 THR THR B . n 
B 2 26  THR 26  333 333 THR THR B . n 
B 2 27  VAL 27  334 334 VAL VAL B . n 
B 2 28  LEU 28  335 335 LEU LEU B . n 
B 2 29  ARG 29  336 336 ARG ARG B . n 
B 2 30  GLN 30  337 337 GLN GLN B . n 
B 2 31  LEU 31  338 338 LEU LEU B . n 
B 2 32  ASP 32  339 339 ASP ASP B . n 
B 2 33  MET 33  340 340 MET MET B . n 
B 2 34  GLU 34  341 341 GLU GLU B . n 
B 2 35  LEU 35  342 342 LEU LEU B . n 
B 2 36  VAL 36  343 343 VAL VAL B . n 
B 2 37  SER 37  344 344 SER SER B . n 
B 2 38  VAL 38  345 345 VAL VAL B . n 
B 2 39  LYS 39  346 346 LYS LYS B . n 
B 2 40  ARG 40  347 347 ARG ARG B . n 
B 2 41  GLN 41  348 348 GLN GLN B . n 
B 2 42  ILE 42  349 349 ILE ILE B . n 
B 2 43  GLN 43  350 350 GLN GLN B . n 
B 2 44  ASN 44  351 351 ASN ASN B . n 
B 2 45  ILE 45  352 352 ILE ILE B . n 
B 2 46  LYS 46  353 353 LYS LYS B . n 
B 2 47  GLN 47  354 354 GLN GLN B . n 
B 2 48  THR 48  355 355 THR THR B . n 
B 2 49  ASN 49  356 356 ASN ASN B . n 
B 2 50  SER 50  357 357 SER SER B . n 
B 2 51  ALA 51  358 358 ALA ALA B . n 
B 2 52  LEU 52  359 359 LEU LEU B . n 
B 2 53  LYS 53  360 360 LYS LYS B . n 
B 2 54  GLU 54  361 361 GLU GLU B . n 
B 2 55  LYS 55  362 362 LYS LYS B . n 
B 2 56  LEU 56  363 363 LEU LEU B . n 
B 2 57  ASP 57  364 364 ASP ASP B . n 
B 2 58  GLY 58  365 365 GLY GLY B . n 
B 2 59  GLY 59  366 366 GLY GLY B . n 
B 2 60  ILE 60  367 367 ILE ILE B . n 
B 2 61  GLU 61  368 368 GLU GLU B . n 
B 2 62  PRO 62  369 369 PRO PRO B . n 
B 2 63  TYR 63  370 370 TYR TYR B . n 
B 2 64  ARG 64  371 371 ARG ARG B . n 
B 2 65  LEU 65  372 372 LEU LEU B . n 
B 2 66  PRO 66  373 373 PRO PRO B . n 
B 2 67  GLU 67  374 374 GLU GLU B . n 
B 2 68  VAL 68  375 375 VAL VAL B . n 
B 2 69  ILE 69  376 376 ILE ILE B . n 
C 3 1   SER 1   257 257 SER SER C . n 
C 3 2   ALA 2   258 258 ALA ALA C . n 
C 3 3   HIS 3   259 259 HIS HIS C . n 
C 3 4   LYS 4   260 260 LYS LYS C . n 
C 3 5   LEU 5   261 261 LEU LEU C . n 
C 3 6   PHE 6   262 262 PHE PHE C . n 
C 3 7   ILE 7   263 263 ILE ILE C . n 
C 3 8   GLY 8   264 264 GLY GLY C . n 
C 3 9   GLY 9   265 265 GLY GLY C . n 
C 3 10  LEU 10  266 266 LEU LEU C . n 
C 3 11  PRO 11  267 267 PRO PRO C . n 
C 3 12  ASN 12  268 268 ASN ASN C . n 
C 3 13  TYR 13  269 269 TYR TYR C . n 
C 3 14  LEU 14  270 270 LEU LEU C . n 
C 3 15  ASN 15  271 271 ASN ASN C . n 
C 3 16  ASP 16  272 272 ASP ASP C . n 
C 3 17  ASP 17  273 273 ASP ASP C . n 
C 3 18  GLN 18  274 274 GLN GLN C . n 
C 3 19  VAL 19  275 275 VAL VAL C . n 
C 3 20  LYS 20  276 276 LYS LYS C . n 
C 3 21  GLU 21  277 277 GLU GLU C . n 
C 3 22  LEU 22  278 278 LEU LEU C . n 
C 3 23  LEU 23  279 279 LEU LEU C . n 
C 3 24  THR 24  280 280 THR THR C . n 
C 3 25  SER 25  281 281 SER SER C . n 
C 3 26  PHE 26  282 282 PHE PHE C . n 
C 3 27  GLY 27  283 283 GLY GLY C . n 
C 3 28  PRO 28  284 284 PRO PRO C . n 
C 3 29  LEU 29  285 285 LEU LEU C . n 
C 3 30  LYS 30  286 286 LYS LYS C . n 
C 3 31  ALA 31  287 287 ALA ALA C . n 
C 3 32  PHE 32  288 288 PHE PHE C . n 
C 3 33  ASN 33  289 289 ASN ASN C . n 
C 3 34  LEU 34  290 290 LEU LEU C . n 
C 3 35  VAL 35  291 291 VAL VAL C . n 
C 3 36  LYS 36  292 292 LYS LYS C . n 
C 3 37  ASP 37  293 293 ASP ASP C . n 
C 3 38  SER 38  294 294 SER SER C . n 
C 3 39  ALA 39  295 295 ALA ALA C . n 
C 3 40  THR 40  296 296 THR THR C . n 
C 3 41  GLY 41  297 297 GLY GLY C . n 
C 3 42  LEU 42  298 298 LEU LEU C . n 
C 3 43  SER 43  299 299 SER SER C . n 
C 3 44  LYS 44  300 300 LYS LYS C . n 
C 3 45  GLY 45  301 301 GLY GLY C . n 
C 3 46  TYR 46  302 302 TYR TYR C . n 
C 3 47  ALA 47  303 303 ALA ALA C . n 
C 3 48  PHE 48  304 304 PHE PHE C . n 
C 3 49  CYS 49  305 305 CYS CYS C . n 
C 3 50  GLU 50  306 306 GLU GLU C . n 
C 3 51  TYR 51  307 307 TYR TYR C . n 
C 3 52  VAL 52  308 308 VAL VAL C . n 
C 3 53  ASP 53  309 309 ASP ASP C . n 
C 3 54  ILE 54  310 310 ILE ILE C . n 
C 3 55  ASN 55  311 311 ASN ASN C . n 
C 3 56  VAL 56  312 312 VAL VAL C . n 
C 3 57  THR 57  313 313 THR THR C . n 
C 3 58  ASP 58  314 314 ASP ASP C . n 
C 3 59  GLN 59  315 315 GLN GLN C . n 
C 3 60  ALA 60  316 316 ALA ALA C . n 
C 3 61  ILE 61  317 317 ILE ILE C . n 
C 3 62  ALA 62  318 318 ALA ALA C . n 
C 3 63  GLY 63  319 319 GLY GLY C . n 
C 3 64  LEU 64  320 320 LEU LEU C . n 
C 3 65  ASN 65  321 321 ASN ASN C . n 
C 3 66  GLY 66  322 322 GLY GLY C . n 
C 3 67  MET 67  323 323 MET MET C . n 
C 3 68  GLN 68  324 324 GLN GLN C . n 
C 3 69  LEU 69  325 325 LEU LEU C . n 
C 3 70  GLY 70  326 326 GLY GLY C . n 
C 3 71  ASP 71  327 327 ASP ASP C . n 
C 3 72  LYS 72  328 328 LYS LYS C . n 
C 3 73  LYS 73  329 329 LYS LYS C . n 
C 3 74  LEU 74  330 330 LEU LEU C . n 
C 3 75  LEU 75  331 331 LEU LEU C . n 
C 3 76  VAL 76  332 332 VAL VAL C . n 
C 3 77  GLN 77  333 333 GLN GLN C . n 
C 3 78  ARG 78  334 334 ARG ARG C . n 
C 3 79  ALA 79  335 335 ALA ALA C . n 
C 3 80  SER 80  336 336 SER SER C . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DWU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DWU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DWU 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9DWU 
_struct.title                        'CoREST complex bound to U2AF2' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DWU 
_struct_keywords.text            'RNA, splicing, melanoma, epigenetics, GENE REGULATION' 
_struct_keywords.pdbx_keywords   'GENE REGULATION' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP KDM1A_HUMAN O60341 ? 1 
;PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVH
RVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG
AMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQ
ALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTAL
CKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNG
YSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSA
VQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAI
LKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPAT
VHGALLSGLREAGRIADQFLGAMYTL
;
171 
2 UNP RCOR1_HUMAN Q9UKL0 ? 2 RKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVI 311 
3 UNP U2AF2_HUMAN P26368 ? 3 
;SAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRAS

;
257 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9DWU A 1 ? 666 ? O60341 171 ? 836 ? 171 836 
2 2 9DWU B 1 ? 69  ? Q9UKL0 311 ? 379 ? 308 376 
3 3 9DWU C 1 ? 80  ? P26368 257 ? 336 ? 257 336 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 2   ? SER A 11  ? SER A 172 SER A 181 1 ? 10 
HELX_P HELX_P2  AA2 THR A 19  ? PHE A 26  ? THR A 189 PHE A 196 1 ? 8  
HELX_P HELX_P3  AA3 PHE A 26  ? SER A 31  ? PHE A 196 SER A 201 1 ? 6  
HELX_P HELX_P4  AA4 PRO A 33  ? ASN A 54  ? PRO A 203 ASN A 224 1 ? 22 
HELX_P HELX_P5  AA5 THR A 60  ? LEU A 68  ? THR A 230 LEU A 238 1 ? 9  
HELX_P HELX_P6  AA6 PRO A 71  ? SER A 74  ? PRO A 241 SER A 244 5 ? 4  
HELX_P HELX_P7  AA7 ASP A 75  ? HIS A 89  ? ASP A 245 HIS A 259 1 ? 15 
HELX_P HELX_P8  AA8 GLY A 117 ? GLY A 131 ? GLY A 287 GLY A 301 1 ? 15 
HELX_P HELX_P9  AA9 PRO A 171 ? VAL A 179 ? PRO A 341 VAL A 349 1 ? 9  
HELX_P HELX_P10 AB1 PRO A 201 ? GLN A 225 ? PRO A 371 GLN A 395 1 ? 25 
HELX_P HELX_P11 AB2 SER A 237 ? SER A 296 ? SER A 407 SER A 466 1 ? 60 
HELX_P HELX_P12 AB3 ASP A 303 ? ASN A 344 ? ASP A 473 ASN A 514 1 ? 42 
HELX_P HELX_P13 AB4 SER A 352 ? ASN A 370 ? SER A 522 ASN A 540 1 ? 19 
HELX_P HELX_P14 AB5 PRO A 373 ? LEU A 377 ? PRO A 543 LEU A 547 5 ? 5  
HELX_P HELX_P15 AB6 ASP A 385 ? GLU A 389 ? ASP A 555 GLU A 559 5 ? 5  
HELX_P HELX_P16 AB7 SER A 402 ? ALA A 409 ? SER A 572 ALA A 579 1 ? 8  
HELX_P HELX_P17 AB8 PRO A 456 ? GLN A 462 ? PRO A 626 GLN A 632 1 ? 7  
HELX_P HELX_P18 AB9 PRO A 474 ? MET A 484 ? PRO A 644 MET A 654 1 ? 11 
HELX_P HELX_P19 AC1 GLY A 539 ? GLU A 546 ? GLY A 709 GLU A 716 1 ? 8  
HELX_P HELX_P20 AC2 SER A 549 ? GLY A 566 ? SER A 719 GLY A 736 1 ? 18 
HELX_P HELX_P21 AC3 GLY A 600 ? GLN A 608 ? GLY A 770 GLN A 778 1 ? 9  
HELX_P HELX_P22 AC4 GLY A 630 ? ILE A 634 ? GLY A 800 ILE A 804 5 ? 5  
HELX_P HELX_P23 AC5 THR A 640 ? GLY A 661 ? THR A 810 GLY A 831 1 ? 22 
HELX_P HELX_P24 AC6 SER B 10  ? SER B 18  ? SER B 317 SER B 325 1 ? 9  
HELX_P HELX_P25 AC7 THR B 22  ? LEU B 56  ? THR B 329 LEU B 363 1 ? 35 
HELX_P HELX_P26 AC8 ILE B 60  ? ARG B 64  ? ILE B 367 ARG B 371 5 ? 5  
HELX_P HELX_P27 AC9 ASN C 15  ? SER C 25  ? ASN C 271 SER C 281 1 ? 11 
HELX_P HELX_P28 AD1 ASP C 53  ? ASN C 65  ? ASP C 309 ASN C 321 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ALA 70  A . ? ALA 240 A PRO 71  A ? PRO 241 A 1 -1.29 
2 PRO 300 A . ? PRO 470 A PRO 301 A ? PRO 471 A 1 0.09  
3 GLN 463 A . ? GLN 633 A PRO 464 A ? PRO 634 A 1 -0.63 
4 VAL 470 A . ? VAL 640 A PRO 471 A ? PRO 641 A 1 -3.50 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 6 ? 
AA5 ? 2 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
AA9 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? parallel      
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ASP A 413 ? LYS A 415 ? ASP A 583 LYS A 585 
AA1 2 ASP A 133 ? LEU A 137 ? ASP A 303 LEU A 307 
AA1 3 LYS A 110 ? ILE A 114 ? LYS A 280 ILE A 284 
AA1 4 ALA A 450 ? CYS A 453 ? ALA A 620 CYS A 623 
AA1 5 LEU A 626 ? PHE A 628 ? LEU A 796 PHE A 798 
AA2 1 THR A 149 ? LYS A 152 ? THR A 319 LYS A 322 
AA2 2 TYR A 155 ? ASP A 158 ? TYR A 325 ASP A 328 
AA3 1 VAL A 163 ? VAL A 164 ? VAL A 333 VAL A 334 
AA3 2 LEU A 395 ? VAL A 397 ? LEU A 565 VAL A 567 
AA3 3 LEU A 183 ? LYS A 185 ? LEU A 353 LYS A 355 
AA4 1 LEU A 192 ? TYR A 193 ? LEU A 362 TYR A 363 
AA4 2 LEU A 507 ? HIS A 510 ? LEU A 677 HIS A 680 
AA4 3 LEU A 523 ? ASN A 526 ? LEU A 693 ASN A 696 
AA4 4 ILE A 532 ? VAL A 537 ? ILE A 702 VAL A 707 
AA4 5 ASN A 490 ? CYS A 495 ? ASN A 660 CYS A 665 
AA4 6 GLU A 575 ? VAL A 578 ? GLU A 745 VAL A 748 
AA5 1 VAL A 230 ? LEU A 231 ? VAL A 400 LEU A 401 
AA5 2 LYS A 234 ? PRO A 235 ? LYS A 404 PRO A 405 
AA6 1 SER A 439 ? CYS A 448 ? SER A 609 CYS A 618 
AA6 2 GLY A 429 ? ASN A 436 ? GLY A 599 ASN A 606 
AA6 3 THR A 418 ? THR A 426 ? THR A 588 THR A 596 
AA6 4 GLN A 468 ? VAL A 470 ? GLN A 638 VAL A 640 
AA7 1 GLY A 485 ? PHE A 486 ? GLY A 655 PHE A 656 
AA7 2 SER A 592 ? TYR A 593 ? SER A 762 TYR A 763 
AA8 1 LEU C 29  ? LYS C 36  ? LEU C 285 LYS C 292 
AA8 2 SER C 43  ? TYR C 51  ? SER C 299 TYR C 307 
AA8 3 LYS C 4   ? GLY C 8   ? LYS C 260 GLY C 264 
AA8 4 LEU C 75  ? ARG C 78  ? LEU C 331 ARG C 334 
AA9 1 GLN C 68  ? LEU C 69  ? GLN C 324 LEU C 325 
AA9 2 LYS C 72  ? LYS C 73  ? LYS C 328 LYS C 329 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LYS A 415 ? O LYS A 585 N LEU A 136 ? N LEU A 306 
AA1 2 3 O THR A 135 ? O THR A 305 N ILE A 113 ? N ILE A 283 
AA1 3 4 N ILE A 114 ? N ILE A 284 O LEU A 452 ? O LEU A 622 
AA1 4 5 N VAL A 451 ? N VAL A 621 O PHE A 627 ? O PHE A 797 
AA2 1 2 N PHE A 150 ? N PHE A 320 O ALA A 157 ? O ALA A 327 
AA3 1 2 N VAL A 164 ? N VAL A 334 O LEU A 395 ? O LEU A 565 
AA3 2 3 O THR A 396 ? O THR A 566 N ALA A 184 ? N ALA A 354 
AA4 1 2 N TYR A 193 ? N TYR A 363 O GLY A 509 ? O GLY A 679 
AA4 2 3 N PHE A 508 ? N PHE A 678 O PHE A 524 ? O PHE A 694 
AA4 3 4 N TRP A 525 ? N TRP A 695 O LEU A 534 ? O LEU A 704 
AA4 4 5 O ALA A 535 ? O ALA A 705 N VAL A 492 ? N VAL A 662 
AA4 5 6 N VAL A 493 ? N VAL A 663 O VAL A 577 ? O VAL A 747 
AA5 1 2 N LEU A 231 ? N LEU A 401 O LYS A 234 ? O LYS A 404 
AA6 1 2 O PHE A 444 ? O PHE A 614 N ALA A 434 ? N ALA A 604 
AA6 2 3 O ILE A 433 ? O ILE A 603 N ARG A 421 ? N ARG A 591 
AA6 3 4 N VAL A 423 ? N VAL A 593 O VAL A 470 ? O VAL A 640 
AA7 1 2 N GLY A 485 ? N GLY A 655 O TYR A 593 ? O TYR A 763 
AA8 1 2 N LYS C 30  ? N LYS C 286 O GLU C 50  ? O GLU C 306 
AA8 2 3 O ALA C 47  ? O ALA C 303 N ILE C 7   ? N ILE C 263 
AA8 3 4 N GLY C 8   ? N GLY C 264 O LEU C 75  ? O LEU C 331 
AA9 1 2 N LEU C 69  ? N LEU C 325 O LYS C 72  ? O LYS C 328 
# 
_pdbx_entry_details.entry_id                   9DWU 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN A 224 ? ? -152.43 78.25  
2 1 SER A 286 ? ? -119.74 52.54  
3 1 MET A 332 ? ? -141.99 -30.86 
4 1 GLN A 348 ? ? -93.85  -66.28 
5 1 ASN A 514 ? ? -115.18 63.60  
6 1 SER A 609 ? ? -160.02 91.07  
7 1 ALA A 757 ? ? -129.70 -53.44 
8 1 PRO A 792 ? ? -59.33  177.66 
9 1 PRO B 373 ? ? -45.14  156.01 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9DWU 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9DWU 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  5.14 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               172429 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Splicing factor U2AF2 bound to the CoREST complex made up of LSD1 and RCOR1' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        9DWU 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9DWU 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9DWU 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-10 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9DWU 
_em_admin.last_update        2025-01-08 
_em_admin.map_release_date   2025-01-08 
_em_admin.title              'CoREST complex bound to U2AF2' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               HEK293F 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.0 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           '#1045461' 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9DWU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . PRO A 1 1   ? 160.491 140.319 157.366 1.00 97.41  ? 171 PRO A N   1 
ATOM 2    C CA  . PRO A 1 1   ? 159.559 140.094 156.249 1.00 97.18  ? 171 PRO A CA  1 
ATOM 3    C C   . PRO A 1 1   ? 160.267 139.785 154.910 1.00 96.84  ? 171 PRO A C   1 
ATOM 4    O O   . PRO A 1 1   ? 161.015 140.634 154.398 1.00 97.10  ? 171 PRO A O   1 
ATOM 5    C CB  . PRO A 1 1   ? 158.771 141.418 156.170 1.00 97.11  ? 171 PRO A CB  1 
ATOM 6    C CG  . PRO A 1 1   ? 159.619 142.453 156.911 1.00 97.07  ? 171 PRO A CG  1 
ATOM 7    C CD  . PRO A 1 1   ? 160.783 141.752 157.572 1.00 97.64  ? 171 PRO A CD  1 
ATOM 8    N N   . SER A 1 2   ? 160.024 138.590 154.353 1.00 96.00  ? 172 SER A N   1 
ATOM 9    C CA  . SER A 1 2   ? 160.637 138.161 153.070 1.00 95.10  ? 172 SER A CA  1 
ATOM 10   C C   . SER A 1 2   ? 159.635 137.738 151.953 1.00 94.27  ? 172 SER A C   1 
ATOM 11   O O   . SER A 1 2   ? 158.412 137.750 152.156 1.00 94.32  ? 172 SER A O   1 
ATOM 12   C CB  . SER A 1 2   ? 161.701 137.067 153.312 1.00 95.23  ? 172 SER A CB  1 
ATOM 13   O OG  . SER A 1 2   ? 161.126 135.841 153.733 1.00 95.04  ? 172 SER A OG  1 
ATOM 14   N N   . GLY A 1 3   ? 160.165 137.376 150.779 1.00 93.03  ? 173 GLY A N   1 
ATOM 15   C CA  . GLY A 1 3   ? 159.346 136.958 149.635 1.00 91.25  ? 173 GLY A CA  1 
ATOM 16   C C   . GLY A 1 3   ? 158.547 138.108 149.046 1.00 90.07  ? 173 GLY A C   1 
ATOM 17   O O   . GLY A 1 3   ? 159.049 139.232 148.936 1.00 90.08  ? 173 GLY A O   1 
ATOM 18   N N   . VAL A 1 4   ? 157.297 137.835 148.673 1.00 88.67  ? 174 VAL A N   1 
ATOM 19   C CA  . VAL A 1 4   ? 156.433 138.870 148.109 1.00 87.04  ? 174 VAL A CA  1 
ATOM 20   C C   . VAL A 1 4   ? 155.933 139.803 149.206 1.00 86.12  ? 174 VAL A C   1 
ATOM 21   O O   . VAL A 1 4   ? 155.625 140.962 148.943 1.00 86.09  ? 174 VAL A O   1 
ATOM 22   C CB  . VAL A 1 4   ? 155.245 138.309 147.276 1.00 87.01  ? 174 VAL A CB  1 
ATOM 23   C CG1 . VAL A 1 4   ? 155.755 137.518 146.081 1.00 86.77  ? 174 VAL A CG1 1 
ATOM 24   C CG2 . VAL A 1 4   ? 154.293 137.478 148.132 1.00 86.95  ? 174 VAL A CG2 1 
ATOM 25   N N   . GLU A 1 5   ? 155.867 139.297 150.433 1.00 84.86  ? 175 GLU A N   1 
ATOM 26   C CA  . GLU A 1 5   ? 155.428 140.094 151.576 1.00 83.86  ? 175 GLU A CA  1 
ATOM 27   C C   . GLU A 1 5   ? 156.504 141.117 151.945 1.00 82.61  ? 175 GLU A C   1 
ATOM 28   O O   . GLU A 1 5   ? 156.190 142.223 152.396 1.00 82.49  ? 175 GLU A O   1 
ATOM 29   C CB  . GLU A 1 5   ? 155.094 139.202 152.771 1.00 84.02  ? 175 GLU A CB  1 
ATOM 30   C CG  . GLU A 1 5   ? 153.794 138.426 152.598 1.00 85.56  ? 175 GLU A CG  1 
ATOM 31   C CD  . GLU A 1 5   ? 153.660 137.271 153.583 1.00 87.25  ? 175 GLU A CD  1 
ATOM 32   O OE1 . GLU A 1 5   ? 154.020 137.451 154.770 1.00 87.88  ? 175 GLU A OE1 1 
ATOM 33   O OE2 . GLU A 1 5   ? 153.186 136.187 153.166 1.00 86.94  ? 175 GLU A OE2 1 
ATOM 34   N N   . GLY A 1 6   ? 157.768 140.739 151.735 1.00 81.01  ? 176 GLY A N   1 
ATOM 35   C CA  . GLY A 1 6   ? 158.905 141.611 152.005 1.00 78.79  ? 176 GLY A CA  1 
ATOM 36   C C   . GLY A 1 6   ? 158.854 142.797 151.055 1.00 77.32  ? 176 GLY A C   1 
ATOM 37   O O   . GLY A 1 6   ? 159.141 143.928 151.442 1.00 77.20  ? 176 GLY A O   1 
ATOM 38   N N   . ALA A 1 7   ? 158.454 142.532 149.813 1.00 75.80  ? 177 ALA A N   1 
ATOM 39   C CA  . ALA A 1 7   ? 158.342 143.570 148.796 1.00 74.19  ? 177 ALA A CA  1 
ATOM 40   C C   . ALA A 1 7   ? 157.312 144.622 149.179 1.00 73.12  ? 177 ALA A C   1 
ATOM 41   O O   . ALA A 1 7   ? 157.548 145.807 148.989 1.00 73.28  ? 177 ALA A O   1 
ATOM 42   C CB  . ALA A 1 7   ? 158.010 142.967 147.452 1.00 74.16  ? 177 ALA A CB  1 
ATOM 43   N N   . ALA A 1 8   ? 156.179 144.197 149.723 1.00 71.90  ? 178 ALA A N   1 
ATOM 44   C CA  . ALA A 1 8   ? 155.143 145.131 150.133 1.00 71.05  ? 178 ALA A CA  1 
ATOM 45   C C   . ALA A 1 8   ? 155.695 146.005 151.261 1.00 70.71  ? 178 ALA A C   1 
ATOM 46   O O   . ALA A 1 8   ? 155.646 147.237 151.191 1.00 70.23  ? 178 ALA A O   1 
ATOM 47   C CB  . ALA A 1 8   ? 153.902 144.388 150.594 1.00 70.73  ? 178 ALA A CB  1 
ATOM 48   N N   . PHE A 1 9   ? 156.241 145.351 152.283 1.00 70.04  ? 179 PHE A N   1 
ATOM 49   C CA  . PHE A 1 9   ? 156.809 146.033 153.415 1.00 69.67  ? 179 PHE A CA  1 
ATOM 50   C C   . PHE A 1 9   ? 157.871 147.044 152.978 1.00 70.14  ? 179 PHE A C   1 
ATOM 51   O O   . PHE A 1 9   ? 157.925 148.165 153.501 1.00 70.48  ? 179 PHE A O   1 
ATOM 52   C CB  . PHE A 1 9   ? 157.410 145.024 154.393 1.00 69.12  ? 179 PHE A CB  1 
ATOM 53   C CG  . PHE A 1 9   ? 158.196 145.650 155.503 1.00 68.31  ? 179 PHE A CG  1 
ATOM 54   C CD1 . PHE A 1 9   ? 157.574 145.992 156.707 1.00 68.26  ? 179 PHE A CD1 1 
ATOM 55   C CD2 . PHE A 1 9   ? 159.560 145.901 155.355 1.00 67.18  ? 179 PHE A CD2 1 
ATOM 56   C CE1 . PHE A 1 9   ? 158.301 146.571 157.756 1.00 67.34  ? 179 PHE A CE1 1 
ATOM 57   C CE2 . PHE A 1 9   ? 160.301 146.478 156.394 1.00 67.60  ? 179 PHE A CE2 1 
ATOM 58   C CZ  . PHE A 1 9   ? 159.670 146.812 157.599 1.00 67.65  ? 179 PHE A CZ  1 
ATOM 59   N N   . GLN A 1 10  ? 158.716 146.646 152.033 1.00 70.08  ? 180 GLN A N   1 
ATOM 60   C CA  . GLN A 1 10  ? 159.774 147.519 151.550 1.00 70.47  ? 180 GLN A CA  1 
ATOM 61   C C   . GLN A 1 10  ? 159.209 148.690 150.721 1.00 70.89  ? 180 GLN A C   1 
ATOM 62   O O   . GLN A 1 10  ? 159.877 149.713 150.535 1.00 71.43  ? 180 GLN A O   1 
ATOM 63   C CB  . GLN A 1 10  ? 160.829 146.690 150.810 1.00 70.43  ? 180 GLN A CB  1 
ATOM 64   C CG  . GLN A 1 10  ? 162.073 147.427 150.338 1.00 71.46  ? 180 GLN A CG  1 
ATOM 65   C CD  . GLN A 1 10  ? 162.810 148.162 151.442 1.00 73.23  ? 180 GLN A CD  1 
ATOM 66   O OE1 . GLN A 1 10  ? 162.892 147.699 152.582 1.00 73.01  ? 180 GLN A OE1 1 
ATOM 67   N NE2 . GLN A 1 10  ? 163.361 149.325 151.097 1.00 74.77  ? 180 GLN A NE2 1 
ATOM 68   N N   . SER A 1 11  ? 157.964 148.556 150.268 1.00 70.66  ? 181 SER A N   1 
ATOM 69   C CA  . SER A 1 11  ? 157.304 149.618 149.508 1.00 70.52  ? 181 SER A CA  1 
ATOM 70   C C   . SER A 1 11  ? 156.279 150.401 150.365 1.00 70.57  ? 181 SER A C   1 
ATOM 71   O O   . SER A 1 11  ? 155.523 151.218 149.845 1.00 70.68  ? 181 SER A O   1 
ATOM 72   C CB  . SER A 1 11  ? 156.619 149.027 148.282 1.00 70.43  ? 181 SER A CB  1 
ATOM 73   O OG  . SER A 1 11  ? 157.569 148.421 147.429 1.00 71.22  ? 181 SER A OG  1 
ATOM 74   N N   . ARG A 1 12  ? 156.265 150.139 151.675 1.00 70.22  ? 182 ARG A N   1 
ATOM 75   C CA  . ARG A 1 12  ? 155.345 150.785 152.627 1.00 69.94  ? 182 ARG A CA  1 
ATOM 76   C C   . ARG A 1 12  ? 153.875 150.476 152.337 1.00 70.02  ? 182 ARG A C   1 
ATOM 77   O O   . ARG A 1 12  ? 152.998 151.323 152.502 1.00 70.27  ? 182 ARG A O   1 
ATOM 78   C CB  . ARG A 1 12  ? 155.601 152.297 152.730 1.00 69.41  ? 182 ARG A CB  1 
ATOM 79   C CG  . ARG A 1 12  ? 157.018 152.628 153.179 1.00 68.55  ? 182 ARG A CG  1 
ATOM 80   C CD  . ARG A 1 12  ? 157.483 153.968 152.644 1.00 67.30  ? 182 ARG A CD  1 
ATOM 81   N NE  . ARG A 1 12  ? 157.239 154.076 151.213 1.00 68.00  ? 182 ARG A NE  1 
ATOM 82   C CZ  . ARG A 1 12  ? 158.068 153.628 150.273 1.00 67.24  ? 182 ARG A CZ  1 
ATOM 83   N NH1 . ARG A 1 12  ? 159.205 153.046 150.621 1.00 69.09  ? 182 ARG A NH1 1 
ATOM 84   N NH2 . ARG A 1 12  ? 157.766 153.764 148.993 1.00 64.70  ? 182 ARG A NH2 1 
ATOM 85   N N   . LEU A 1 13  ? 153.610 149.241 151.924 1.00 69.93  ? 183 LEU A N   1 
ATOM 86   C CA  . LEU A 1 13  ? 152.256 148.811 151.609 1.00 69.62  ? 183 LEU A CA  1 
ATOM 87   C C   . LEU A 1 13  ? 151.851 147.645 152.487 1.00 69.99  ? 183 LEU A C   1 
ATOM 88   O O   . LEU A 1 13  ? 152.693 146.829 152.858 1.00 70.16  ? 183 LEU A O   1 
ATOM 89   C CB  . LEU A 1 13  ? 152.159 148.410 150.137 1.00 69.33  ? 183 LEU A CB  1 
ATOM 90   C CG  . LEU A 1 13  ? 152.443 149.489 149.079 1.00 67.85  ? 183 LEU A CG  1 
ATOM 91   C CD1 . LEU A 1 13  ? 152.318 148.916 147.678 1.00 65.77  ? 183 LEU A CD1 1 
ATOM 92   C CD2 . LEU A 1 13  ? 151.515 150.674 149.234 1.00 65.48  ? 183 LEU A CD2 1 
ATOM 93   N N   . PRO A 1 14  ? 150.559 147.562 152.840 1.00 70.33  ? 184 PRO A N   1 
ATOM 94   C CA  . PRO A 1 14  ? 150.073 146.359 153.528 1.00 70.57  ? 184 PRO A CA  1 
ATOM 95   C C   . PRO A 1 14  ? 150.002 145.231 152.496 1.00 71.47  ? 184 PRO A C   1 
ATOM 96   O O   . PRO A 1 14  ? 149.408 145.414 151.420 1.00 71.69  ? 184 PRO A O   1 
ATOM 97   C CB  . PRO A 1 14  ? 148.689 146.768 154.016 1.00 70.35  ? 184 PRO A CB  1 
ATOM 98   C CG  . PRO A 1 14  ? 148.270 147.892 153.097 1.00 70.53  ? 184 PRO A CG  1 
ATOM 99   C CD  . PRO A 1 14  ? 149.501 148.562 152.606 1.00 69.80  ? 184 PRO A CD  1 
ATOM 100  N N   . HIS A 1 15  ? 150.636 144.097 152.790 1.00 72.19  ? 185 HIS A N   1 
ATOM 101  C CA  . HIS A 1 15  ? 150.672 142.972 151.845 1.00 72.99  ? 185 HIS A CA  1 
ATOM 102  C C   . HIS A 1 15  ? 149.360 142.270 151.554 1.00 73.32  ? 185 HIS A C   1 
ATOM 103  O O   . HIS A 1 15  ? 149.173 141.743 150.462 1.00 73.55  ? 185 HIS A O   1 
ATOM 104  C CB  . HIS A 1 15  ? 151.719 141.930 152.264 1.00 72.98  ? 185 HIS A CB  1 
ATOM 105  C CG  . HIS A 1 15  ? 151.325 141.100 153.449 1.00 74.23  ? 185 HIS A CG  1 
ATOM 106  N ND1 . HIS A 1 15  ? 150.724 139.862 153.327 1.00 75.06  ? 185 HIS A ND1 1 
ATOM 107  C CD2 . HIS A 1 15  ? 151.464 141.319 154.781 1.00 75.35  ? 185 HIS A CD2 1 
ATOM 108  C CE1 . HIS A 1 15  ? 150.502 139.360 154.530 1.00 75.17  ? 185 HIS A CE1 1 
ATOM 109  N NE2 . HIS A 1 15  ? 150.943 140.225 155.430 1.00 75.22  ? 185 HIS A NE2 1 
ATOM 110  N N   . ASP A 1 16  ? 148.469 142.247 152.535 1.00 73.92  ? 186 ASP A N   1 
ATOM 111  C CA  . ASP A 1 16  ? 147.195 141.532 152.431 1.00 74.76  ? 186 ASP A CA  1 
ATOM 112  C C   . ASP A 1 16  ? 145.975 142.412 152.295 1.00 74.86  ? 186 ASP A C   1 
ATOM 113  O O   . ASP A 1 16  ? 144.855 141.966 152.535 1.00 74.87  ? 186 ASP A O   1 
ATOM 114  C CB  . ASP A 1 16  ? 147.028 140.684 153.701 1.00 74.66  ? 186 ASP A CB  1 
ATOM 115  C CG  . ASP A 1 16  ? 147.162 141.517 154.993 1.00 76.02  ? 186 ASP A CG  1 
ATOM 116  O OD1 . ASP A 1 16  ? 147.207 142.778 154.919 1.00 76.93  ? 186 ASP A OD1 1 
ATOM 117  O OD2 . ASP A 1 16  ? 147.231 140.913 156.088 1.00 76.36  ? 186 ASP A OD2 1 
ATOM 118  N N   . ARG A 1 17  ? 146.190 143.660 151.915 1.00 75.34  ? 187 ARG A N   1 
ATOM 119  C CA  . ARG A 1 17  ? 145.101 144.611 151.813 1.00 76.05  ? 187 ARG A CA  1 
ATOM 120  C C   . ARG A 1 17  ? 145.396 145.659 150.753 1.00 75.29  ? 187 ARG A C   1 
ATOM 121  O O   . ARG A 1 17  ? 146.551 146.053 150.565 1.00 75.18  ? 187 ARG A O   1 
ATOM 122  C CB  . ARG A 1 17  ? 144.977 145.295 153.180 1.00 76.25  ? 187 ARG A CB  1 
ATOM 123  C CG  . ARG A 1 17  ? 143.621 145.850 153.541 1.00 78.16  ? 187 ARG A CG  1 
ATOM 124  C CD  . ARG A 1 17  ? 143.613 146.346 155.003 1.00 78.26  ? 187 ARG A CD  1 
ATOM 125  N NE  . ARG A 1 17  ? 144.445 147.542 155.189 1.00 82.51  ? 187 ARG A NE  1 
ATOM 126  C CZ  . ARG A 1 17  ? 145.483 147.621 156.022 1.00 83.14  ? 187 ARG A CZ  1 
ATOM 127  N NH1 . ARG A 1 17  ? 145.828 146.578 156.770 1.00 84.23  ? 187 ARG A NH1 1 
ATOM 128  N NH2 . ARG A 1 17  ? 146.174 148.749 156.117 1.00 82.54  ? 187 ARG A NH2 1 
ATOM 129  N N   . MET A 1 18  ? 144.347 146.116 150.076 1.00 74.95  ? 188 MET A N   1 
ATOM 130  C CA  . MET A 1 18  ? 144.475 147.139 149.041 1.00 74.08  ? 188 MET A CA  1 
ATOM 131  C C   . MET A 1 18  ? 144.402 148.511 149.700 1.00 74.01  ? 188 MET A C   1 
ATOM 132  O O   . MET A 1 18  ? 143.595 148.722 150.605 1.00 73.95  ? 188 MET A O   1 
ATOM 133  C CB  . MET A 1 18  ? 143.360 147.009 148.005 1.00 73.84  ? 188 MET A CB  1 
ATOM 134  C CG  . MET A 1 18  ? 143.437 145.766 147.134 1.00 73.85  ? 188 MET A CG  1 
ATOM 135  S SD  . MET A 1 18  ? 142.120 145.646 145.884 1.00 73.66  ? 188 MET A SD  1 
ATOM 136  C CE  . MET A 1 18  ? 142.638 146.866 144.673 1.00 73.56  ? 188 MET A CE  1 
ATOM 137  N N   . THR A 1 19  ? 145.243 149.441 149.252 1.00 73.71  ? 189 THR A N   1 
ATOM 138  C CA  . THR A 1 19  ? 145.242 150.785 149.806 1.00 73.34  ? 189 THR A CA  1 
ATOM 139  C C   . THR A 1 19  ? 144.157 151.647 149.172 1.00 73.47  ? 189 THR A C   1 
ATOM 140  O O   . THR A 1 19  ? 143.541 151.279 148.165 1.00 73.89  ? 189 THR A O   1 
ATOM 141  C CB  . THR A 1 19  ? 146.602 151.519 149.617 1.00 73.39  ? 189 THR A CB  1 
ATOM 142  O OG1 . THR A 1 19  ? 146.833 151.806 148.227 1.00 73.71  ? 189 THR A OG1 1 
ATOM 143  C CG2 . THR A 1 19  ? 147.757 150.715 150.176 1.00 72.81  ? 189 THR A CG2 1 
ATOM 144  N N   . SER A 1 20  ? 143.953 152.810 149.770 1.00 73.45  ? 190 SER A N   1 
ATOM 145  C CA  . SER A 1 20  ? 143.001 153.800 149.323 1.00 73.53  ? 190 SER A CA  1 
ATOM 146  C C   . SER A 1 20  ? 143.320 154.246 147.891 1.00 73.61  ? 190 SER A C   1 
ATOM 147  O O   . SER A 1 20  ? 142.426 154.433 147.073 1.00 73.57  ? 190 SER A O   1 
ATOM 148  C CB  . SER A 1 20  ? 143.098 154.996 150.254 1.00 73.39  ? 190 SER A CB  1 
ATOM 149  O OG  . SER A 1 20  ? 142.013 155.858 150.043 1.00 74.79  ? 190 SER A OG  1 
ATOM 150  N N   . GLN A 1 21  ? 144.610 154.407 147.602 1.00 73.83  ? 191 GLN A N   1 
ATOM 151  C CA  . GLN A 1 21  ? 145.090 154.804 146.288 1.00 73.95  ? 191 GLN A CA  1 
ATOM 152  C C   . GLN A 1 21  ? 144.761 153.684 145.292 1.00 73.58  ? 191 GLN A C   1 
ATOM 153  O O   . GLN A 1 21  ? 144.277 153.940 144.198 1.00 73.77  ? 191 GLN A O   1 
ATOM 154  C CB  . GLN A 1 21  ? 146.592 155.078 146.368 1.00 74.14  ? 191 GLN A CB  1 
ATOM 155  C CG  . GLN A 1 21  ? 147.296 155.454 145.077 1.00 77.29  ? 191 GLN A CG  1 
ATOM 156  C CD  . GLN A 1 21  ? 148.579 156.246 145.362 1.00 82.98  ? 191 GLN A CD  1 
ATOM 157  O OE1 . GLN A 1 21  ? 148.528 157.466 145.570 1.00 85.24  ? 191 GLN A OE1 1 
ATOM 158  N NE2 . GLN A 1 21  ? 149.730 155.557 145.393 1.00 83.10  ? 191 GLN A NE2 1 
ATOM 159  N N   . GLU A 1 22  ? 144.997 152.440 145.697 1.00 73.15  ? 192 GLU A N   1 
ATOM 160  C CA  . GLU A 1 22  ? 144.705 151.299 144.857 1.00 72.75  ? 192 GLU A CA  1 
ATOM 161  C C   . GLU A 1 22  ? 143.200 151.181 144.626 1.00 72.28  ? 192 GLU A C   1 
ATOM 162  O O   . GLU A 1 22  ? 142.767 150.781 143.543 1.00 72.42  ? 192 GLU A O   1 
ATOM 163  C CB  . GLU A 1 22  ? 145.277 150.021 145.461 1.00 72.64  ? 192 GLU A CB  1 
ATOM 164  C CG  . GLU A 1 22  ? 146.792 149.900 145.322 1.00 72.79  ? 192 GLU A CG  1 
ATOM 165  C CD  . GLU A 1 22  ? 147.406 148.844 146.248 1.00 73.75  ? 192 GLU A CD  1 
ATOM 166  O OE1 . GLU A 1 22  ? 146.806 148.515 147.311 1.00 72.97  ? 192 GLU A OE1 1 
ATOM 167  O OE2 . GLU A 1 22  ? 148.508 148.345 145.905 1.00 75.40  ? 192 GLU A OE2 1 
ATOM 168  N N   . ALA A 1 23  ? 142.401 151.558 145.621 1.00 71.48  ? 193 ALA A N   1 
ATOM 169  C CA  . ALA A 1 23  ? 140.953 151.494 145.477 1.00 71.15  ? 193 ALA A CA  1 
ATOM 170  C C   . ALA A 1 23  ? 140.503 152.428 144.369 1.00 71.12  ? 193 ALA A C   1 
ATOM 171  O O   . ALA A 1 23  ? 139.682 152.065 143.532 1.00 71.21  ? 193 ALA A O   1 
ATOM 172  C CB  . ALA A 1 23  ? 140.264 151.856 146.772 1.00 70.87  ? 193 ALA A CB  1 
ATOM 173  N N   . ALA A 1 24  ? 141.056 153.637 144.377 1.00 71.01  ? 194 ALA A N   1 
ATOM 174  C CA  . ALA A 1 24  ? 140.735 154.665 143.397 1.00 71.03  ? 194 ALA A CA  1 
ATOM 175  C C   . ALA A 1 24  ? 141.036 154.260 141.953 1.00 71.19  ? 194 ALA A C   1 
ATOM 176  O O   . ALA A 1 24  ? 140.328 154.671 141.044 1.00 71.01  ? 194 ALA A O   1 
ATOM 177  C CB  . ALA A 1 24  ? 141.466 155.970 143.749 1.00 70.82  ? 194 ALA A CB  1 
ATOM 178  N N   . CYS A 1 25  ? 142.089 153.474 141.747 1.00 71.30  ? 195 CYS A N   1 
ATOM 179  C CA  . CYS A 1 25  ? 142.473 153.049 140.408 1.00 71.99  ? 195 CYS A CA  1 
ATOM 180  C C   . CYS A 1 25  ? 141.902 151.693 140.022 1.00 71.74  ? 195 CYS A C   1 
ATOM 181  O O   . CYS A 1 25  ? 141.818 151.355 138.840 1.00 72.26  ? 195 CYS A O   1 
ATOM 182  C CB  . CYS A 1 25  ? 143.987 152.992 140.298 1.00 72.41  ? 195 CYS A CB  1 
ATOM 183  S SG  . CYS A 1 25  ? 144.806 154.547 140.664 1.00 76.00  ? 195 CYS A SG  1 
ATOM 184  N N   . PHE A 1 26  ? 141.525 150.908 141.021 1.00 71.14  ? 196 PHE A N   1 
ATOM 185  C CA  . PHE A 1 26  ? 140.977 149.596 140.784 1.00 70.15  ? 196 PHE A CA  1 
ATOM 186  C C   . PHE A 1 26  ? 139.664 149.451 141.549 1.00 69.35  ? 196 PHE A C   1 
ATOM 187  O O   . PHE A 1 26  ? 139.503 148.533 142.348 1.00 69.11  ? 196 PHE A O   1 
ATOM 188  C CB  . PHE A 1 26  ? 141.994 148.528 141.196 1.00 70.45  ? 196 PHE A CB  1 
ATOM 189  C CG  . PHE A 1 26  ? 143.310 148.614 140.452 1.00 71.30  ? 196 PHE A CG  1 
ATOM 190  C CD1 . PHE A 1 26  ? 144.351 149.423 140.925 1.00 71.71  ? 196 PHE A CD1 1 
ATOM 191  C CD2 . PHE A 1 26  ? 143.516 147.876 139.292 1.00 70.65  ? 196 PHE A CD2 1 
ATOM 192  C CE1 . PHE A 1 26  ? 145.562 149.502 140.244 1.00 71.07  ? 196 PHE A CE1 1 
ATOM 193  C CE2 . PHE A 1 26  ? 144.729 147.951 138.597 1.00 70.33  ? 196 PHE A CE2 1 
ATOM 194  C CZ  . PHE A 1 26  ? 145.746 148.759 139.071 1.00 70.78  ? 196 PHE A CZ  1 
ATOM 195  N N   . PRO A 1 27  ? 138.704 150.350 141.286 1.00 68.65  ? 197 PRO A N   1 
ATOM 196  C CA  . PRO A 1 27  ? 137.409 150.301 141.959 1.00 68.21  ? 197 PRO A CA  1 
ATOM 197  C C   . PRO A 1 27  ? 136.683 149.013 141.645 1.00 67.83  ? 197 PRO A C   1 
ATOM 198  O O   . PRO A 1 27  ? 135.944 148.512 142.476 1.00 67.88  ? 197 PRO A O   1 
ATOM 199  C CB  . PRO A 1 27  ? 136.644 151.475 141.345 1.00 68.17  ? 197 PRO A CB  1 
ATOM 200  C CG  . PRO A 1 27  ? 137.325 151.740 140.042 1.00 68.30  ? 197 PRO A CG  1 
ATOM 201  C CD  . PRO A 1 27  ? 138.767 151.449 140.311 1.00 68.40  ? 197 PRO A CD  1 
ATOM 202  N N   . ASP A 1 28  ? 136.903 148.487 140.447 1.00 67.59  ? 198 ASP A N   1 
ATOM 203  C CA  . ASP A 1 28  ? 136.277 147.242 140.007 1.00 67.79  ? 198 ASP A CA  1 
ATOM 204  C C   . ASP A 1 28  ? 136.742 146.077 140.868 1.00 67.43  ? 198 ASP A C   1 
ATOM 205  O O   . ASP A 1 28  ? 135.964 145.190 141.207 1.00 67.47  ? 198 ASP A O   1 
ATOM 206  C CB  . ASP A 1 28  ? 136.603 146.968 138.527 1.00 67.92  ? 198 ASP A CB  1 
ATOM 207  C CG  . ASP A 1 28  ? 138.121 147.088 138.210 1.00 69.26  ? 198 ASP A CG  1 
ATOM 208  O OD1 . ASP A 1 28  ? 138.790 148.096 138.582 1.00 66.91  ? 198 ASP A OD1 1 
ATOM 209  O OD2 . ASP A 1 28  ? 138.641 146.149 137.574 1.00 71.41  ? 198 ASP A OD2 1 
ATOM 210  N N   . ILE A 1 29  ? 138.018 146.104 141.229 1.00 67.13  ? 199 ILE A N   1 
ATOM 211  C CA  . ILE A 1 29  ? 138.612 145.055 142.028 1.00 66.81  ? 199 ILE A CA  1 
ATOM 212  C C   . ILE A 1 29  ? 138.271 145.128 143.515 1.00 66.47  ? 199 ILE A C   1 
ATOM 213  O O   . ILE A 1 29  ? 137.784 144.149 144.082 1.00 66.45  ? 199 ILE A O   1 
ATOM 214  C CB  . ILE A 1 29  ? 140.120 144.968 141.764 1.00 66.83  ? 199 ILE A CB  1 
ATOM 215  C CG1 . ILE A 1 29  ? 140.314 144.325 140.394 1.00 67.60  ? 199 ILE A CG1 1 
ATOM 216  C CG2 . ILE A 1 29  ? 140.819 144.151 142.838 1.00 65.94  ? 199 ILE A CG2 1 
ATOM 217  C CD1 . ILE A 1 29  ? 141.547 144.742 139.705 1.00 70.39  ? 199 ILE A CD1 1 
ATOM 218  N N   . ILE A 1 30  ? 138.488 146.281 144.138 1.00 66.04  ? 200 ILE A N   1 
ATOM 219  C CA  . ILE A 1 30  ? 138.177 146.404 145.557 1.00 65.71  ? 200 ILE A CA  1 
ATOM 220  C C   . ILE A 1 30  ? 136.692 146.174 145.893 1.00 65.87  ? 200 ILE A C   1 
ATOM 221  O O   . ILE A 1 30  ? 136.377 145.745 146.997 1.00 65.93  ? 200 ILE A O   1 
ATOM 222  C CB  . ILE A 1 30  ? 138.761 147.699 146.204 1.00 65.72  ? 200 ILE A CB  1 
ATOM 223  C CG1 . ILE A 1 30  ? 138.804 147.535 147.731 1.00 64.94  ? 200 ILE A CG1 1 
ATOM 224  C CG2 . ILE A 1 30  ? 137.981 148.941 145.776 1.00 64.68  ? 200 ILE A CG2 1 
ATOM 225  C CD1 . ILE A 1 30  ? 139.745 148.449 148.440 1.00 64.43  ? 200 ILE A CD1 1 
ATOM 226  N N   . SER A 1 31  ? 135.793 146.412 144.948 1.00 66.06  ? 201 SER A N   1 
ATOM 227  C CA  . SER A 1 31  ? 134.376 146.194 145.206 1.00 66.59  ? 201 SER A CA  1 
ATOM 228  C C   . SER A 1 31  ? 133.910 144.797 144.788 1.00 67.34  ? 201 SER A C   1 
ATOM 229  O O   . SER A 1 31  ? 132.747 144.448 144.982 1.00 67.20  ? 201 SER A O   1 
ATOM 230  C CB  . SER A 1 31  ? 133.547 147.246 144.491 1.00 66.26  ? 201 SER A CB  1 
ATOM 231  O OG  . SER A 1 31  ? 133.754 147.174 143.095 1.00 66.24  ? 201 SER A OG  1 
ATOM 232  N N   . GLY A 1 32  ? 134.817 144.013 144.203 1.00 68.43  ? 202 GLY A N   1 
ATOM 233  C CA  . GLY A 1 32  ? 134.511 142.658 143.731 1.00 69.65  ? 202 GLY A CA  1 
ATOM 234  C C   . GLY A 1 32  ? 134.852 141.569 144.729 1.00 70.79  ? 202 GLY A C   1 
ATOM 235  O O   . GLY A 1 32  ? 135.221 141.861 145.863 1.00 71.07  ? 202 GLY A O   1 
ATOM 236  N N   . PRO A 1 33  ? 134.700 140.298 144.325 1.00 71.71  ? 203 PRO A N   1 
ATOM 237  C CA  . PRO A 1 33  ? 135.027 139.133 145.171 1.00 72.42  ? 203 PRO A CA  1 
ATOM 238  C C   . PRO A 1 33  ? 136.434 139.134 145.799 1.00 73.13  ? 203 PRO A C   1 
ATOM 239  O O   . PRO A 1 33  ? 137.397 139.606 145.184 1.00 73.26  ? 203 PRO A O   1 
ATOM 240  C CB  . PRO A 1 33  ? 134.874 137.939 144.216 1.00 72.35  ? 203 PRO A CB  1 
ATOM 241  C CG  . PRO A 1 33  ? 134.665 138.515 142.845 1.00 71.95  ? 203 PRO A CG  1 
ATOM 242  C CD  . PRO A 1 33  ? 134.146 139.896 143.020 1.00 71.73  ? 203 PRO A CD  1 
ATOM 243  N N   . GLN A 1 34  ? 136.531 138.596 147.016 1.00 73.93  ? 204 GLN A N   1 
ATOM 244  C CA  . GLN A 1 34  ? 137.794 138.509 147.753 1.00 74.78  ? 204 GLN A CA  1 
ATOM 245  C C   . GLN A 1 34  ? 138.918 137.846 146.956 1.00 74.70  ? 204 GLN A C   1 
ATOM 246  O O   . GLN A 1 34  ? 140.065 138.308 146.980 1.00 74.83  ? 204 GLN A O   1 
ATOM 247  C CB  . GLN A 1 34  ? 137.591 137.788 149.092 1.00 75.04  ? 204 GLN A CB  1 
ATOM 248  C CG  . GLN A 1 34  ? 137.252 138.719 150.254 1.00 77.52  ? 204 GLN A CG  1 
ATOM 249  C CD  . GLN A 1 34  ? 138.425 139.622 150.652 1.00 80.88  ? 204 GLN A CD  1 
ATOM 250  O OE1 . GLN A 1 34  ? 139.399 139.165 151.257 1.00 82.70  ? 204 GLN A OE1 1 
ATOM 251  N NE2 . GLN A 1 34  ? 138.331 140.909 150.314 1.00 81.88  ? 204 GLN A NE2 1 
ATOM 252  N N   . GLN A 1 35  ? 138.576 136.776 146.243 1.00 74.71  ? 205 GLN A N   1 
ATOM 253  C CA  . GLN A 1 35  ? 139.535 136.037 145.423 1.00 74.68  ? 205 GLN A CA  1 
ATOM 254  C C   . GLN A 1 35  ? 140.269 136.928 144.412 1.00 74.18  ? 205 GLN A C   1 
ATOM 255  O O   . GLN A 1 35  ? 141.487 136.842 144.284 1.00 74.30  ? 205 GLN A O   1 
ATOM 256  C CB  . GLN A 1 35  ? 138.857 134.854 144.714 1.00 74.97  ? 205 GLN A CB  1 
ATOM 257  C CG  . GLN A 1 35  ? 139.840 133.829 144.122 1.00 76.85  ? 205 GLN A CG  1 
ATOM 258  C CD  . GLN A 1 35  ? 140.985 133.475 145.086 1.00 79.15  ? 205 GLN A CD  1 
ATOM 259  O OE1 . GLN A 1 35  ? 140.788 132.774 146.083 1.00 79.29  ? 205 GLN A OE1 1 
ATOM 260  N NE2 . GLN A 1 35  ? 142.185 133.966 144.783 1.00 80.10  ? 205 GLN A NE2 1 
ATOM 261  N N   . THR A 1 36  ? 139.529 137.782 143.709 1.00 73.45  ? 206 THR A N   1 
ATOM 262  C CA  . THR A 1 36  ? 140.126 138.673 142.719 1.00 72.98  ? 206 THR A CA  1 
ATOM 263  C C   . THR A 1 36  ? 141.069 139.668 143.394 1.00 72.71  ? 206 THR A C   1 
ATOM 264  O O   . THR A 1 36  ? 142.147 139.964 142.875 1.00 72.53  ? 206 THR A O   1 
ATOM 265  C CB  . THR A 1 36  ? 139.044 139.378 141.877 1.00 73.14  ? 206 THR A CB  1 
ATOM 266  O OG1 . THR A 1 36  ? 138.317 138.387 141.136 1.00 73.20  ? 206 THR A OG1 1 
ATOM 267  C CG2 . THR A 1 36  ? 139.652 140.377 140.896 1.00 73.00  ? 206 THR A CG2 1 
ATOM 268  N N   . GLN A 1 37  ? 140.673 140.147 144.570 1.00 72.32  ? 207 GLN A N   1 
ATOM 269  C CA  . GLN A 1 37  ? 141.500 141.071 145.334 1.00 71.93  ? 207 GLN A CA  1 
ATOM 270  C C   . GLN A 1 37  ? 142.831 140.391 145.662 1.00 71.73  ? 207 GLN A C   1 
ATOM 271  O O   . GLN A 1 37  ? 143.899 141.004 145.533 1.00 71.41  ? 207 GLN A O   1 
ATOM 272  C CB  . GLN A 1 37  ? 140.781 141.524 146.603 1.00 71.81  ? 207 GLN A CB  1 
ATOM 273  C CG  . GLN A 1 37  ? 139.548 142.353 146.322 1.00 71.83  ? 207 GLN A CG  1 
ATOM 274  C CD  . GLN A 1 37  ? 138.826 142.793 147.575 1.00 71.96  ? 207 GLN A CD  1 
ATOM 275  O OE1 . GLN A 1 37  ? 139.446 143.095 148.587 1.00 72.22  ? 207 GLN A OE1 1 
ATOM 276  N NE2 . GLN A 1 37  ? 137.501 142.845 147.507 1.00 72.20  ? 207 GLN A NE2 1 
ATOM 277  N N   . LYS A 1 38  ? 142.762 139.113 146.044 1.00 71.45  ? 208 LYS A N   1 
ATOM 278  C CA  . LYS A 1 38  ? 143.966 138.350 146.348 1.00 71.46  ? 208 LYS A CA  1 
ATOM 279  C C   . LYS A 1 38  ? 144.854 138.199 145.105 1.00 71.19  ? 208 LYS A C   1 
ATOM 280  O O   . LYS A 1 38  ? 146.080 138.246 145.215 1.00 71.59  ? 208 LYS A O   1 
ATOM 281  C CB  . LYS A 1 38  ? 143.633 136.987 146.951 1.00 71.60  ? 208 LYS A CB  1 
ATOM 282  C CG  . LYS A 1 38  ? 143.394 137.012 148.456 1.00 72.46  ? 208 LYS A CG  1 
ATOM 283  C CD  . LYS A 1 38  ? 143.101 135.602 148.977 1.00 73.76  ? 208 LYS A CD  1 
ATOM 284  C CE  . LYS A 1 38  ? 142.652 135.605 150.440 1.00 74.05  ? 208 LYS A CE  1 
ATOM 285  N NZ  . LYS A 1 38  ? 141.901 134.355 150.746 1.00 74.02  ? 208 LYS A NZ  1 
ATOM 286  N N   . VAL A 1 39  ? 144.244 138.052 143.929 1.00 70.52  ? 209 VAL A N   1 
ATOM 287  C CA  . VAL A 1 39  ? 145.016 137.932 142.691 1.00 69.98  ? 209 VAL A CA  1 
ATOM 288  C C   . VAL A 1 39  ? 145.737 139.253 142.437 1.00 69.92  ? 209 VAL A C   1 
ATOM 289  O O   . VAL A 1 39  ? 146.923 139.270 142.104 1.00 70.21  ? 209 VAL A O   1 
ATOM 290  C CB  . VAL A 1 39  ? 144.143 137.564 141.463 1.00 70.01  ? 209 VAL A CB  1 
ATOM 291  C CG1 . VAL A 1 39  ? 144.993 137.504 140.188 1.00 69.21  ? 209 VAL A CG1 1 
ATOM 292  C CG2 . VAL A 1 39  ? 143.433 136.240 141.684 1.00 69.64  ? 209 VAL A CG2 1 
ATOM 293  N N   . PHE A 1 40  ? 145.020 140.359 142.607 1.00 69.53  ? 210 PHE A N   1 
ATOM 294  C CA  . PHE A 1 40  ? 145.599 141.672 142.412 1.00 69.10  ? 210 PHE A CA  1 
ATOM 295  C C   . PHE A 1 40  ? 146.775 141.886 143.358 1.00 69.01  ? 210 PHE A C   1 
ATOM 296  O O   . PHE A 1 40  ? 147.865 142.285 142.938 1.00 69.16  ? 210 PHE A O   1 
ATOM 297  C CB  . PHE A 1 40  ? 144.550 142.759 142.647 1.00 69.03  ? 210 PHE A CB  1 
ATOM 298  C CG  . PHE A 1 40  ? 145.130 144.140 142.765 1.00 69.01  ? 210 PHE A CG  1 
ATOM 299  C CD1 . PHE A 1 40  ? 145.351 144.913 141.635 1.00 69.06  ? 210 PHE A CD1 1 
ATOM 300  C CD2 . PHE A 1 40  ? 145.478 144.658 144.010 1.00 69.17  ? 210 PHE A CD2 1 
ATOM 301  C CE1 . PHE A 1 40  ? 145.897 146.200 141.747 1.00 70.56  ? 210 PHE A CE1 1 
ATOM 302  C CE2 . PHE A 1 40  ? 146.025 145.934 144.141 1.00 68.82  ? 210 PHE A CE2 1 
ATOM 303  C CZ  . PHE A 1 40  ? 146.240 146.708 143.010 1.00 69.55  ? 210 PHE A CZ  1 
ATOM 304  N N   . LEU A 1 41  ? 146.551 141.624 144.639 1.00 68.72  ? 211 LEU A N   1 
ATOM 305  C CA  . LEU A 1 41  ? 147.597 141.820 145.631 1.00 68.46  ? 211 LEU A CA  1 
ATOM 306  C C   . LEU A 1 41  ? 148.855 141.021 145.315 1.00 68.71  ? 211 LEU A C   1 
ATOM 307  O O   . LEU A 1 41  ? 149.970 141.514 145.506 1.00 69.12  ? 211 LEU A O   1 
ATOM 308  C CB  . LEU A 1 41  ? 147.094 141.508 147.041 1.00 68.03  ? 211 LEU A CB  1 
ATOM 309  C CG  . LEU A 1 41  ? 146.035 142.432 147.640 1.00 66.56  ? 211 LEU A CG  1 
ATOM 310  C CD1 . LEU A 1 41  ? 145.403 141.780 148.878 1.00 63.93  ? 211 LEU A CD1 1 
ATOM 311  C CD2 . LEU A 1 41  ? 146.618 143.799 147.962 1.00 64.24  ? 211 LEU A CD2 1 
ATOM 312  N N   . PHE A 1 42  ? 148.687 139.798 144.826 1.00 68.80  ? 212 PHE A N   1 
ATOM 313  C CA  . PHE A 1 42  ? 149.846 138.973 144.499 1.00 68.85  ? 212 PHE A CA  1 
ATOM 314  C C   . PHE A 1 42  ? 150.614 139.565 143.322 1.00 68.81  ? 212 PHE A C   1 
ATOM 315  O O   . PHE A 1 42  ? 151.844 139.631 143.344 1.00 69.18  ? 212 PHE A O   1 
ATOM 316  C CB  . PHE A 1 42  ? 149.455 137.526 144.207 1.00 68.72  ? 212 PHE A CB  1 
ATOM 317  C CG  . PHE A 1 42  ? 150.631 136.633 143.955 1.00 68.95  ? 212 PHE A CG  1 
ATOM 318  C CD1 . PHE A 1 42  ? 151.424 136.191 145.008 1.00 69.77  ? 212 PHE A CD1 1 
ATOM 319  C CD2 . PHE A 1 42  ? 150.959 136.243 142.662 1.00 69.30  ? 212 PHE A CD2 1 
ATOM 320  C CE1 . PHE A 1 42  ? 152.526 135.362 144.780 1.00 69.89  ? 212 PHE A CE1 1 
ATOM 321  C CE2 . PHE A 1 42  ? 152.055 135.413 142.421 1.00 69.83  ? 212 PHE A CE2 1 
ATOM 322  C CZ  . PHE A 1 42  ? 152.839 134.972 143.483 1.00 69.81  ? 212 PHE A CZ  1 
ATOM 323  N N   . ILE A 1 43  ? 149.880 140.005 142.305 1.00 68.43  ? 213 ILE A N   1 
ATOM 324  C CA  . ILE A 1 43  ? 150.489 140.596 141.136 1.00 68.02  ? 213 ILE A CA  1 
ATOM 325  C C   . ILE A 1 43  ? 151.239 141.848 141.573 1.00 68.14  ? 213 ILE A C   1 
ATOM 326  O O   . ILE A 1 43  ? 152.386 142.059 141.187 1.00 68.24  ? 213 ILE A O   1 
ATOM 327  C CB  . ILE A 1 43  ? 149.435 140.915 140.058 1.00 68.10  ? 213 ILE A CB  1 
ATOM 328  C CG1 . ILE A 1 43  ? 148.922 139.613 139.424 1.00 67.52  ? 213 ILE A CG1 1 
ATOM 329  C CG2 . ILE A 1 43  ? 150.023 141.846 138.998 1.00 67.78  ? 213 ILE A CG2 1 
ATOM 330  C CD1 . ILE A 1 43  ? 147.683 139.774 138.545 1.00 67.62  ? 213 ILE A CD1 1 
ATOM 331  N N   . ARG A 1 44  ? 150.600 142.657 142.409 1.00 67.95  ? 214 ARG A N   1 
ATOM 332  C CA  . ARG A 1 44  ? 151.230 143.874 142.889 1.00 68.19  ? 214 ARG A CA  1 
ATOM 333  C C   . ARG A 1 44  ? 152.500 143.577 143.700 1.00 68.25  ? 214 ARG A C   1 
ATOM 334  O O   . ARG A 1 44  ? 153.563 144.145 143.434 1.00 68.53  ? 214 ARG A O   1 
ATOM 335  C CB  . ARG A 1 44  ? 150.231 144.743 143.668 1.00 68.12  ? 214 ARG A CB  1 
ATOM 336  C CG  . ARG A 1 44  ? 150.830 146.003 144.295 1.00 67.91  ? 214 ARG A CG  1 
ATOM 337  C CD  . ARG A 1 44  ? 151.009 145.816 145.801 1.00 68.58  ? 214 ARG A CD  1 
ATOM 338  N NE  . ARG A 1 44  ? 149.911 146.402 146.564 1.00 68.58  ? 214 ARG A NE  1 
ATOM 339  C CZ  . ARG A 1 44  ? 149.578 146.048 147.806 1.00 69.81  ? 214 ARG A CZ  1 
ATOM 340  N NH1 . ARG A 1 44  ? 150.242 145.081 148.440 1.00 68.33  ? 214 ARG A NH1 1 
ATOM 341  N NH2 . ARG A 1 44  ? 148.564 146.657 148.415 1.00 69.47  ? 214 ARG A NH2 1 
ATOM 342  N N   . ASN A 1 45  ? 152.391 142.687 144.678 1.00 67.99  ? 215 ASN A N   1 
ATOM 343  C CA  . ASN A 1 45  ? 153.540 142.342 145.498 1.00 67.80  ? 215 ASN A CA  1 
ATOM 344  C C   . ASN A 1 45  ? 154.675 141.737 144.676 1.00 67.87  ? 215 ASN A C   1 
ATOM 345  O O   . ASN A 1 45  ? 155.841 142.083 144.855 1.00 67.90  ? 215 ASN A O   1 
ATOM 346  C CB  . ASN A 1 45  ? 153.122 141.415 146.641 1.00 67.74  ? 215 ASN A CB  1 
ATOM 347  C CG  . ASN A 1 45  ? 152.238 142.110 147.661 1.00 67.58  ? 215 ASN A CG  1 
ATOM 348  O OD1 . ASN A 1 45  ? 152.252 143.337 147.785 1.00 67.93  ? 215 ASN A OD1 1 
ATOM 349  N ND2 . ASN A 1 45  ? 151.470 141.329 148.405 1.00 66.82  ? 215 ASN A ND2 1 
ATOM 350  N N   . ARG A 1 46  ? 154.327 140.851 143.753 1.00 67.92  ? 216 ARG A N   1 
ATOM 351  C CA  . ARG A 1 46  ? 155.329 140.216 142.908 1.00 68.00  ? 216 ARG A CA  1 
ATOM 352  C C   . ARG A 1 46  ? 156.030 141.224 141.988 1.00 67.99  ? 216 ARG A C   1 
ATOM 353  O O   . ARG A 1 46  ? 157.249 141.177 141.822 1.00 68.19  ? 216 ARG A O   1 
ATOM 354  C CB  . ARG A 1 46  ? 154.712 139.069 142.109 1.00 67.86  ? 216 ARG A CB  1 
ATOM 355  C CG  . ARG A 1 46  ? 155.714 138.271 141.320 1.00 68.16  ? 216 ARG A CG  1 
ATOM 356  C CD  . ARG A 1 46  ? 156.522 137.304 142.163 1.00 68.15  ? 216 ARG A CD  1 
ATOM 357  N NE  . ARG A 1 46  ? 157.298 136.445 141.272 1.00 70.61  ? 216 ARG A NE  1 
ATOM 358  C CZ  . ARG A 1 46  ? 158.629 136.402 141.203 1.00 71.36  ? 216 ARG A CZ  1 
ATOM 359  N NH1 . ARG A 1 46  ? 159.385 137.149 142.006 1.00 70.99  ? 216 ARG A NH1 1 
ATOM 360  N NH2 . ARG A 1 46  ? 159.205 135.582 140.329 1.00 70.58  ? 216 ARG A NH2 1 
ATOM 361  N N   . THR A 1 47  ? 155.266 142.141 141.404 1.00 67.91  ? 217 THR A N   1 
ATOM 362  C CA  . THR A 1 47  ? 155.843 143.144 140.522 1.00 67.97  ? 217 THR A CA  1 
ATOM 363  C C   . THR A 1 47  ? 156.836 143.989 141.316 1.00 68.11  ? 217 THR A C   1 
ATOM 364  O O   . THR A 1 47  ? 157.917 144.325 140.826 1.00 68.25  ? 217 THR A O   1 
ATOM 365  C CB  . THR A 1 47  ? 154.761 144.010 139.887 1.00 67.86  ? 217 THR A CB  1 
ATOM 366  O OG1 . THR A 1 47  ? 153.815 143.159 139.230 1.00 69.19  ? 217 THR A OG1 1 
ATOM 367  C CG2 . THR A 1 47  ? 155.359 144.954 138.867 1.00 67.59  ? 217 THR A CG2 1 
ATOM 368  N N   . LEU A 1 48  ? 156.475 144.291 142.560 1.00 68.01  ? 218 LEU A N   1 
ATOM 369  C CA  . LEU A 1 48  ? 157.332 145.050 143.437 1.00 67.96  ? 218 LEU A CA  1 
ATOM 370  C C   . LEU A 1 48  ? 158.580 144.226 143.754 1.00 68.27  ? 218 LEU A C   1 
ATOM 371  O O   . LEU A 1 48  ? 159.682 144.763 143.824 1.00 68.81  ? 218 LEU A O   1 
ATOM 372  C CB  . LEU A 1 48  ? 156.590 145.415 144.722 1.00 67.61  ? 218 LEU A CB  1 
ATOM 373  C CG  . LEU A 1 48  ? 155.491 146.473 144.595 1.00 67.21  ? 218 LEU A CG  1 
ATOM 374  C CD1 . LEU A 1 48  ? 154.638 146.506 145.848 1.00 65.97  ? 218 LEU A CD1 1 
ATOM 375  C CD2 . LEU A 1 48  ? 156.068 147.851 144.294 1.00 65.64  ? 218 LEU A CD2 1 
ATOM 376  N N   . GLN A 1 49  ? 158.413 142.920 143.922 1.00 68.16  ? 219 GLN A N   1 
ATOM 377  C CA  . GLN A 1 49  ? 159.550 142.080 144.227 1.00 68.32  ? 219 GLN A CA  1 
ATOM 378  C C   . GLN A 1 49  ? 160.573 142.086 143.101 1.00 68.57  ? 219 GLN A C   1 
ATOM 379  O O   . GLN A 1 49  ? 161.781 142.214 143.354 1.00 68.77  ? 219 GLN A O   1 
ATOM 380  C CB  . GLN A 1 49  ? 159.121 140.654 144.557 1.00 68.12  ? 219 GLN A CB  1 
ATOM 381  C CG  . GLN A 1 49  ? 160.274 139.792 145.047 1.00 68.21  ? 219 GLN A CG  1 
ATOM 382  C CD  . GLN A 1 49  ? 159.875 138.351 145.321 1.00 68.45  ? 219 GLN A CD  1 
ATOM 383  O OE1 . GLN A 1 49  ? 158.886 137.855 144.788 1.00 69.78  ? 219 GLN A OE1 1 
ATOM 384  N NE2 . GLN A 1 49  ? 160.652 137.672 146.156 1.00 68.05  ? 219 GLN A NE2 1 
ATOM 385  N N   . LEU A 1 50  ? 160.095 141.958 141.864 1.00 68.54  ? 220 LEU A N   1 
ATOM 386  C CA  . LEU A 1 50  ? 160.989 141.939 140.705 1.00 68.48  ? 220 LEU A CA  1 
ATOM 387  C C   . LEU A 1 50  ? 161.795 143.227 140.612 1.00 68.55  ? 220 LEU A C   1 
ATOM 388  O O   . LEU A 1 50  ? 162.998 143.192 140.343 1.00 68.64  ? 220 LEU A O   1 
ATOM 389  C CB  . LEU A 1 50  ? 160.220 141.679 139.410 1.00 68.34  ? 220 LEU A CB  1 
ATOM 390  C CG  . LEU A 1 50  ? 159.439 140.367 139.348 1.00 67.77  ? 220 LEU A CG  1 
ATOM 391  C CD1 . LEU A 1 50  ? 158.420 140.422 138.223 1.00 66.73  ? 220 LEU A CD1 1 
ATOM 392  C CD2 . LEU A 1 50  ? 160.375 139.176 139.195 1.00 67.30  ? 220 LEU A CD2 1 
ATOM 393  N N   . TRP A 1 51  ? 161.140 144.354 140.869 1.00 68.37  ? 221 TRP A N   1 
ATOM 394  C CA  . TRP A 1 51  ? 161.816 145.636 140.820 1.00 68.60  ? 221 TRP A CA  1 
ATOM 395  C C   . TRP A 1 51  ? 162.847 145.749 141.936 1.00 69.25  ? 221 TRP A C   1 
ATOM 396  O O   . TRP A 1 51  ? 164.005 146.088 141.689 1.00 69.53  ? 221 TRP A O   1 
ATOM 397  C CB  . TRP A 1 51  ? 160.809 146.777 140.905 1.00 68.07  ? 221 TRP A CB  1 
ATOM 398  C CG  . TRP A 1 51  ? 161.408 148.094 141.310 1.00 67.76  ? 221 TRP A CG  1 
ATOM 399  C CD1 . TRP A 1 51  ? 161.197 148.757 142.482 1.00 67.08  ? 221 TRP A CD1 1 
ATOM 400  C CD2 . TRP A 1 51  ? 162.311 148.904 140.553 1.00 66.96  ? 221 TRP A CD2 1 
ATOM 401  N NE1 . TRP A 1 51  ? 161.906 149.931 142.504 1.00 66.22  ? 221 TRP A NE1 1 
ATOM 402  C CE2 . TRP A 1 51  ? 162.603 150.046 141.333 1.00 66.89  ? 221 TRP A CE2 1 
ATOM 403  C CE3 . TRP A 1 51  ? 162.896 148.783 139.291 1.00 66.82  ? 221 TRP A CE3 1 
ATOM 404  C CZ2 . TRP A 1 51  ? 163.454 151.060 140.890 1.00 67.65  ? 221 TRP A CZ2 1 
ATOM 405  C CZ3 . TRP A 1 51  ? 163.752 149.791 138.856 1.00 67.27  ? 221 TRP A CZ3 1 
ATOM 406  C CH2 . TRP A 1 51  ? 164.021 150.917 139.655 1.00 67.14  ? 221 TRP A CH2 1 
ATOM 407  N N   . LEU A 1 52  ? 162.428 145.451 143.160 1.00 69.80  ? 222 LEU A N   1 
ATOM 408  C CA  . LEU A 1 52  ? 163.317 145.542 144.310 1.00 70.24  ? 222 LEU A CA  1 
ATOM 409  C C   . LEU A 1 52  ? 164.524 144.622 144.216 1.00 70.97  ? 222 LEU A C   1 
ATOM 410  O O   . LEU A 1 52  ? 165.605 144.984 144.674 1.00 71.23  ? 222 LEU A O   1 
ATOM 411  C CB  . LEU A 1 52  ? 162.548 145.334 145.613 1.00 69.88  ? 222 LEU A CB  1 
ATOM 412  C CG  . LEU A 1 52  ? 161.464 146.386 145.904 1.00 69.41  ? 222 LEU A CG  1 
ATOM 413  C CD1 . LEU A 1 52  ? 160.634 145.946 147.087 1.00 68.23  ? 222 LEU A CD1 1 
ATOM 414  C CD2 . LEU A 1 52  ? 162.035 147.799 146.132 1.00 67.29  ? 222 LEU A CD2 1 
ATOM 415  N N   . ASP A 1 53  ? 164.344 143.454 143.600 1.00 71.87  ? 223 ASP A N   1 
ATOM 416  C CA  . ASP A 1 53  ? 165.433 142.482 143.426 1.00 72.65  ? 223 ASP A CA  1 
ATOM 417  C C   . ASP A 1 53  ? 166.555 143.017 142.547 1.00 72.69  ? 223 ASP A C   1 
ATOM 418  O O   . ASP A 1 53  ? 167.704 142.600 142.676 1.00 72.87  ? 223 ASP A O   1 
ATOM 419  C CB  . ASP A 1 53  ? 164.905 141.186 142.803 1.00 73.02  ? 223 ASP A CB  1 
ATOM 420  C CG  . ASP A 1 53  ? 164.365 140.214 143.837 1.00 74.57  ? 223 ASP A CG  1 
ATOM 421  O OD1 . ASP A 1 53  ? 164.117 140.625 145.000 1.00 76.27  ? 223 ASP A OD1 1 
ATOM 422  O OD2 . ASP A 1 53  ? 164.183 139.032 143.473 1.00 75.60  ? 223 ASP A OD2 1 
ATOM 423  N N   . ASN A 1 54  ? 166.207 143.917 141.633 1.00 72.89  ? 224 ASN A N   1 
ATOM 424  C CA  . ASN A 1 54  ? 167.173 144.503 140.721 1.00 72.84  ? 224 ASN A CA  1 
ATOM 425  C C   . ASN A 1 54  ? 166.744 145.895 140.278 1.00 72.41  ? 224 ASN A C   1 
ATOM 426  O O   . ASN A 1 54  ? 166.238 146.071 139.173 1.00 72.61  ? 224 ASN A O   1 
ATOM 427  C CB  . ASN A 1 54  ? 167.389 143.587 139.512 1.00 73.18  ? 224 ASN A CB  1 
ATOM 428  C CG  . ASN A 1 54  ? 168.623 143.959 138.716 1.00 74.04  ? 224 ASN A CG  1 
ATOM 429  O OD1 . ASN A 1 54  ? 169.452 144.770 139.157 1.00 74.72  ? 224 ASN A OD1 1 
ATOM 430  N ND2 . ASN A 1 54  ? 168.754 143.370 137.530 1.00 74.39  ? 224 ASN A ND2 1 
ATOM 431  N N   . PRO A 1 55  ? 166.948 146.894 141.148 1.00 72.05  ? 225 PRO A N   1 
ATOM 432  C CA  . PRO A 1 55  ? 166.528 148.257 140.862 1.00 71.64  ? 225 PRO A CA  1 
ATOM 433  C C   . PRO A 1 55  ? 167.468 148.998 139.907 1.00 71.57  ? 225 PRO A C   1 
ATOM 434  O O   . PRO A 1 55  ? 167.242 150.174 139.641 1.00 71.48  ? 225 PRO A O   1 
ATOM 435  C CB  . PRO A 1 55  ? 166.571 148.912 142.236 1.00 71.78  ? 225 PRO A CB  1 
ATOM 436  C CG  . PRO A 1 55  ? 167.676 148.199 142.935 1.00 71.32  ? 225 PRO A CG  1 
ATOM 437  C CD  . PRO A 1 55  ? 167.601 146.786 142.469 1.00 71.72  ? 225 PRO A CD  1 
ATOM 438  N N   . LYS A 1 56  ? 168.509 148.329 139.411 1.00 71.43  ? 226 LYS A N   1 
ATOM 439  C CA  . LYS A 1 56  ? 169.463 148.955 138.486 1.00 71.33  ? 226 LYS A CA  1 
ATOM 440  C C   . LYS A 1 56  ? 169.002 148.928 137.014 1.00 71.21  ? 226 LYS A C   1 
ATOM 441  O O   . LYS A 1 56  ? 169.611 149.571 136.156 1.00 71.31  ? 226 LYS A O   1 
ATOM 442  C CB  . LYS A 1 56  ? 170.861 148.355 138.646 1.00 71.29  ? 226 LYS A CB  1 
ATOM 443  C CG  . LYS A 1 56  ? 171.623 148.852 139.881 1.00 71.43  ? 226 LYS A CG  1 
ATOM 444  C CD  . LYS A 1 56  ? 172.954 148.132 140.056 1.00 71.68  ? 226 LYS A CD  1 
ATOM 445  C CE  . LYS A 1 56  ? 172.755 146.681 140.521 1.00 73.39  ? 226 LYS A CE  1 
ATOM 446  N NZ  . LYS A 1 56  ? 173.944 145.800 140.249 1.00 73.05  ? 226 LYS A NZ  1 
ATOM 447  N N   . ILE A 1 57  ? 167.930 148.190 136.725 1.00 70.95  ? 227 ILE A N   1 
ATOM 448  C CA  . ILE A 1 57  ? 167.381 148.119 135.365 1.00 70.97  ? 227 ILE A CA  1 
ATOM 449  C C   . ILE A 1 57  ? 165.871 148.357 135.375 1.00 70.52  ? 227 ILE A C   1 
ATOM 450  O O   . ILE A 1 57  ? 165.184 148.049 136.356 1.00 70.78  ? 227 ILE A O   1 
ATOM 451  C CB  . ILE A 1 57  ? 167.677 146.777 134.619 1.00 71.38  ? 227 ILE A CB  1 
ATOM 452  C CG1 . ILE A 1 57  ? 166.993 145.592 135.318 1.00 72.28  ? 227 ILE A CG1 1 
ATOM 453  C CG2 . ILE A 1 57  ? 169.194 146.560 134.425 1.00 71.37  ? 227 ILE A CG2 1 
ATOM 454  C CD1 . ILE A 1 57  ? 166.654 144.424 134.381 1.00 74.48  ? 227 ILE A CD1 1 
ATOM 455  N N   . GLN A 1 58  ? 165.366 148.906 134.275 1.00 69.79  ? 228 GLN A N   1 
ATOM 456  C CA  . GLN A 1 58  ? 163.955 149.190 134.121 1.00 68.95  ? 228 GLN A CA  1 
ATOM 457  C C   . GLN A 1 58  ? 163.149 147.902 134.084 1.00 68.89  ? 228 GLN A C   1 
ATOM 458  O O   . GLN A 1 58  ? 163.452 146.992 133.300 1.00 68.96  ? 228 GLN A O   1 
ATOM 459  C CB  . GLN A 1 58  ? 163.726 149.969 132.822 1.00 68.85  ? 228 GLN A CB  1 
ATOM 460  C CG  . GLN A 1 58  ? 162.270 150.339 132.553 1.00 68.30  ? 228 GLN A CG  1 
ATOM 461  C CD  . GLN A 1 58  ? 161.994 150.781 131.116 1.00 68.52  ? 228 GLN A CD  1 
ATOM 462  O OE1 . GLN A 1 58  ? 162.885 150.839 130.265 1.00 67.93  ? 228 GLN A OE1 1 
ATOM 463  N NE2 . GLN A 1 58  ? 160.738 151.091 130.846 1.00 68.60  ? 228 GLN A NE2 1 
ATOM 464  N N   . LEU A 1 59  ? 162.121 147.824 134.924 1.00 68.64  ? 229 LEU A N   1 
ATOM 465  C CA  . LEU A 1 59  ? 161.249 146.654 134.935 1.00 68.59  ? 229 LEU A CA  1 
ATOM 466  C C   . LEU A 1 59  ? 160.095 146.937 133.960 1.00 68.77  ? 229 LEU A C   1 
ATOM 467  O O   . LEU A 1 59  ? 159.258 147.790 134.218 1.00 68.66  ? 229 LEU A O   1 
ATOM 468  C CB  . LEU A 1 59  ? 160.740 146.334 136.345 1.00 68.14  ? 229 LEU A CB  1 
ATOM 469  C CG  . LEU A 1 59  ? 159.742 145.172 136.472 1.00 68.04  ? 229 LEU A CG  1 
ATOM 470  C CD1 . LEU A 1 59  ? 160.397 143.809 136.252 1.00 67.45  ? 229 LEU A CD1 1 
ATOM 471  C CD2 . LEU A 1 59  ? 159.050 145.218 137.823 1.00 68.14  ? 229 LEU A CD2 1 
ATOM 472  N N   . THR A 1 60  ? 160.081 146.236 132.831 1.00 69.18  ? 230 THR A N   1 
ATOM 473  C CA  . THR A 1 60  ? 159.040 146.440 131.818 1.00 69.76  ? 230 THR A CA  1 
ATOM 474  C C   . THR A 1 60  ? 157.868 145.490 131.989 1.00 70.29  ? 230 THR A C   1 
ATOM 475  O O   . THR A 1 60  ? 157.988 144.455 132.644 1.00 70.48  ? 230 THR A O   1 
ATOM 476  C CB  . THR A 1 60  ? 159.573 146.241 130.399 1.00 69.27  ? 230 THR A CB  1 
ATOM 477  O OG1 . THR A 1 60  ? 159.891 144.859 130.215 1.00 70.03  ? 230 THR A OG1 1 
ATOM 478  C CG2 . THR A 1 60  ? 160.806 147.094 130.145 1.00 68.80  ? 230 THR A CG2 1 
ATOM 479  N N   . PHE A 1 61  ? 156.741 145.844 131.379 1.00 70.98  ? 231 PHE A N   1 
ATOM 480  C CA  . PHE A 1 61  ? 155.540 145.020 131.433 1.00 71.68  ? 231 PHE A CA  1 
ATOM 481  C C   . PHE A 1 61  ? 155.862 143.625 130.885 1.00 72.30  ? 231 PHE A C   1 
ATOM 482  O O   . PHE A 1 61  ? 155.526 142.620 131.514 1.00 72.25  ? 231 PHE A O   1 
ATOM 483  C CB  . PHE A 1 61  ? 154.384 145.695 130.669 1.00 71.56  ? 231 PHE A CB  1 
ATOM 484  C CG  . PHE A 1 61  ? 153.266 144.763 130.294 1.00 71.44  ? 231 PHE A CG  1 
ATOM 485  C CD1 . PHE A 1 61  ? 152.584 144.033 131.263 1.00 71.21  ? 231 PHE A CD1 1 
ATOM 486  C CD2 . PHE A 1 61  ? 152.887 144.621 128.958 1.00 72.31  ? 231 PHE A CD2 1 
ATOM 487  C CE1 . PHE A 1 61  ? 151.551 143.157 130.901 1.00 71.99  ? 231 PHE A CE1 1 
ATOM 488  C CE2 . PHE A 1 61  ? 151.848 143.751 128.583 1.00 71.52  ? 231 PHE A CE2 1 
ATOM 489  C CZ  . PHE A 1 61  ? 151.178 143.020 129.556 1.00 71.46  ? 231 PHE A CZ  1 
ATOM 490  N N   . GLU A 1 62  ? 156.544 143.573 129.739 1.00 73.10  ? 232 GLU A N   1 
ATOM 491  C CA  . GLU A 1 62  ? 156.929 142.300 129.122 1.00 74.03  ? 232 GLU A CA  1 
ATOM 492  C C   . GLU A 1 62  ? 157.746 141.458 130.090 1.00 74.04  ? 232 GLU A C   1 
ATOM 493  O O   . GLU A 1 62  ? 157.453 140.276 130.283 1.00 74.18  ? 232 GLU A O   1 
ATOM 494  C CB  . GLU A 1 62  ? 157.725 142.513 127.825 1.00 74.43  ? 232 GLU A CB  1 
ATOM 495  C CG  . GLU A 1 62  ? 156.880 142.736 126.563 1.00 76.13  ? 232 GLU A CG  1 
ATOM 496  C CD  . GLU A 1 62  ? 156.227 144.134 126.484 1.00 79.10  ? 232 GLU A CD  1 
ATOM 497  O OE1 . GLU A 1 62  ? 156.410 144.994 127.407 1.00 78.44  ? 232 GLU A OE1 1 
ATOM 498  O OE2 . GLU A 1 62  ? 155.527 144.362 125.467 1.00 79.87  ? 232 GLU A OE2 1 
ATOM 499  N N   . ALA A 1 63  ? 158.760 142.076 130.696 1.00 74.00  ? 233 ALA A N   1 
ATOM 500  C CA  . ALA A 1 63  ? 159.636 141.399 131.647 1.00 74.14  ? 233 ALA A CA  1 
ATOM 501  C C   . ALA A 1 63  ? 158.841 140.817 132.811 1.00 74.30  ? 233 ALA A C   1 
ATOM 502  O O   . ALA A 1 63  ? 159.081 139.686 133.236 1.00 74.45  ? 233 ALA A O   1 
ATOM 503  C CB  . ALA A 1 63  ? 160.726 142.350 132.150 1.00 74.14  ? 233 ALA A CB  1 
ATOM 504  N N   . THR A 1 64  ? 157.883 141.600 133.303 1.00 74.46  ? 234 THR A N   1 
ATOM 505  C CA  . THR A 1 64  ? 157.020 141.206 134.408 1.00 74.44  ? 234 THR A CA  1 
ATOM 506  C C   . THR A 1 64  ? 156.190 139.964 134.059 1.00 74.78  ? 234 THR A C   1 
ATOM 507  O O   . THR A 1 64  ? 156.245 138.947 134.761 1.00 74.85  ? 234 THR A O   1 
ATOM 508  C CB  . THR A 1 64  ? 156.084 142.364 134.793 1.00 74.21  ? 234 THR A CB  1 
ATOM 509  O OG1 . THR A 1 64  ? 156.859 143.494 135.205 1.00 73.94  ? 234 THR A OG1 1 
ATOM 510  C CG2 . THR A 1 64  ? 155.155 141.953 135.911 1.00 74.14  ? 234 THR A CG2 1 
ATOM 511  N N   . LEU A 1 65  ? 155.434 140.055 132.969 1.00 75.02  ? 235 LEU A N   1 
ATOM 512  C CA  . LEU A 1 65  ? 154.579 138.965 132.518 1.00 75.45  ? 235 LEU A CA  1 
ATOM 513  C C   . LEU A 1 65  ? 155.339 137.650 132.360 1.00 75.94  ? 235 LEU A C   1 
ATOM 514  O O   . LEU A 1 65  ? 154.835 136.594 132.739 1.00 76.00  ? 235 LEU A O   1 
ATOM 515  C CB  . LEU A 1 65  ? 153.886 139.344 131.205 1.00 75.40  ? 235 LEU A CB  1 
ATOM 516  C CG  . LEU A 1 65  ? 152.676 138.517 130.767 1.00 75.22  ? 235 LEU A CG  1 
ATOM 517  C CD1 . LEU A 1 65  ? 151.501 138.737 131.706 1.00 75.49  ? 235 LEU A CD1 1 
ATOM 518  C CD2 . LEU A 1 65  ? 152.288 138.870 129.344 1.00 75.33  ? 235 LEU A CD2 1 
ATOM 519  N N   . GLN A 1 66  ? 156.551 137.726 131.815 1.00 76.62  ? 236 GLN A N   1 
ATOM 520  C CA  . GLN A 1 66  ? 157.383 136.547 131.600 1.00 77.36  ? 236 GLN A CA  1 
ATOM 521  C C   . GLN A 1 66  ? 157.802 135.878 132.909 1.00 77.64  ? 236 GLN A C   1 
ATOM 522  O O   . GLN A 1 66  ? 157.879 134.648 132.982 1.00 77.88  ? 236 GLN A O   1 
ATOM 523  C CB  . GLN A 1 66  ? 158.608 136.903 130.738 1.00 77.42  ? 236 GLN A CB  1 
ATOM 524  C CG  . GLN A 1 66  ? 159.552 135.729 130.401 1.00 78.71  ? 236 GLN A CG  1 
ATOM 525  C CD  . GLN A 1 66  ? 158.936 134.671 129.475 1.00 80.32  ? 236 GLN A CD  1 
ATOM 526  O OE1 . GLN A 1 66  ? 157.828 134.839 128.958 1.00 81.25  ? 236 GLN A OE1 1 
ATOM 527  N NE2 . GLN A 1 66  ? 159.666 133.576 129.262 1.00 80.16  ? 236 GLN A NE2 1 
ATOM 528  N N   . GLN A 1 67  ? 158.052 136.678 133.940 1.00 78.08  ? 237 GLN A N   1 
ATOM 529  C CA  . GLN A 1 67  ? 158.476 136.139 135.235 1.00 78.59  ? 237 GLN A CA  1 
ATOM 530  C C   . GLN A 1 67  ? 157.354 135.708 136.184 1.00 78.77  ? 237 GLN A C   1 
ATOM 531  O O   . GLN A 1 67  ? 157.613 135.215 137.281 1.00 78.95  ? 237 GLN A O   1 
ATOM 532  C CB  . GLN A 1 67  ? 159.491 137.060 135.905 1.00 78.52  ? 237 GLN A CB  1 
ATOM 533  C CG  . GLN A 1 67  ? 160.895 136.865 135.346 1.00 79.37  ? 237 GLN A CG  1 
ATOM 534  C CD  . GLN A 1 67  ? 161.862 137.944 135.789 1.00 81.01  ? 237 GLN A CD  1 
ATOM 535  O OE1 . GLN A 1 67  ? 162.830 137.666 136.504 1.00 81.67  ? 237 GLN A OE1 1 
ATOM 536  N NE2 . GLN A 1 67  ? 161.608 139.185 135.374 1.00 80.60  ? 237 GLN A NE2 1 
ATOM 537  N N   . LEU A 1 68  ? 156.109 135.863 135.746 1.00 79.01  ? 238 LEU A N   1 
ATOM 538  C CA  . LEU A 1 68  ? 154.964 135.441 136.536 1.00 79.18  ? 238 LEU A CA  1 
ATOM 539  C C   . LEU A 1 68  ? 154.582 134.031 136.101 1.00 79.60  ? 238 LEU A C   1 
ATOM 540  O O   . LEU A 1 68  ? 154.735 133.665 134.927 1.00 79.72  ? 238 LEU A O   1 
ATOM 541  C CB  . LEU A 1 68  ? 153.779 136.372 136.316 1.00 78.99  ? 238 LEU A CB  1 
ATOM 542  C CG  . LEU A 1 68  ? 153.712 137.683 137.091 1.00 78.60  ? 238 LEU A CG  1 
ATOM 543  C CD1 . LEU A 1 68  ? 152.696 138.597 136.444 1.00 77.71  ? 238 LEU A CD1 1 
ATOM 544  C CD2 . LEU A 1 68  ? 153.362 137.436 138.553 1.00 78.03  ? 238 LEU A CD2 1 
ATOM 545  N N   . GLU A 1 69  ? 154.083 133.238 137.042 1.00 79.93  ? 239 GLU A N   1 
ATOM 546  C CA  . GLU A 1 69  ? 153.673 131.869 136.735 1.00 80.09  ? 239 GLU A CA  1 
ATOM 547  C C   . GLU A 1 69  ? 152.146 131.756 136.696 1.00 80.09  ? 239 GLU A C   1 
ATOM 548  O O   . GLU A 1 69  ? 151.435 132.681 137.098 1.00 80.09  ? 239 GLU A O   1 
ATOM 549  C CB  . GLU A 1 69  ? 154.273 130.878 137.744 1.00 80.15  ? 239 GLU A CB  1 
ATOM 550  C CG  . GLU A 1 69  ? 155.770 130.607 137.564 1.00 80.74  ? 239 GLU A CG  1 
ATOM 551  C CD  . GLU A 1 69  ? 156.152 129.149 137.841 1.00 82.03  ? 239 GLU A CD  1 
ATOM 552  O OE1 . GLU A 1 69  ? 155.729 128.249 137.073 1.00 81.95  ? 239 GLU A OE1 1 
ATOM 553  O OE2 . GLU A 1 69  ? 156.891 128.902 138.818 1.00 82.52  ? 239 GLU A OE2 1 
ATOM 554  N N   . ALA A 1 70  ? 151.647 130.627 136.198 1.00 80.24  ? 240 ALA A N   1 
ATOM 555  C CA  . ALA A 1 70  ? 150.209 130.382 136.123 1.00 80.29  ? 240 ALA A CA  1 
ATOM 556  C C   . ALA A 1 70  ? 149.640 130.327 137.553 1.00 80.36  ? 240 ALA A C   1 
ATOM 557  O O   . ALA A 1 70  ? 150.348 129.939 138.481 1.00 80.39  ? 240 ALA A O   1 
ATOM 558  C CB  . ALA A 1 70  ? 149.933 129.078 135.371 1.00 80.09  ? 240 ALA A CB  1 
ATOM 559  N N   . PRO A 1 71  ? 148.376 130.748 137.747 1.00 80.45  ? 241 PRO A N   1 
ATOM 560  C CA  . PRO A 1 71  ? 147.446 131.291 136.762 1.00 80.45  ? 241 PRO A CA  1 
ATOM 561  C C   . PRO A 1 71  ? 147.510 132.812 136.647 1.00 80.40  ? 241 PRO A C   1 
ATOM 562  O O   . PRO A 1 71  ? 146.756 133.400 135.873 1.00 80.52  ? 241 PRO A O   1 
ATOM 563  C CB  . PRO A 1 71  ? 146.086 130.874 137.322 1.00 80.54  ? 241 PRO A CB  1 
ATOM 564  C CG  . PRO A 1 71  ? 146.286 130.838 138.824 1.00 80.53  ? 241 PRO A CG  1 
ATOM 565  C CD  . PRO A 1 71  ? 147.765 130.671 139.090 1.00 80.46  ? 241 PRO A CD  1 
ATOM 566  N N   . TYR A 1 72  ? 148.399 133.438 137.414 1.00 80.28  ? 242 TYR A N   1 
ATOM 567  C CA  . TYR A 1 72  ? 148.545 134.896 137.419 1.00 80.12  ? 242 TYR A CA  1 
ATOM 568  C C   . TYR A 1 72  ? 148.938 135.491 136.073 1.00 80.16  ? 242 TYR A C   1 
ATOM 569  O O   . TYR A 1 72  ? 148.423 136.546 135.692 1.00 80.31  ? 242 TYR A O   1 
ATOM 570  C CB  . TYR A 1 72  ? 149.515 135.333 138.518 1.00 79.94  ? 242 TYR A CB  1 
ATOM 571  C CG  . TYR A 1 72  ? 149.135 134.788 139.875 1.00 79.66  ? 242 TYR A CG  1 
ATOM 572  C CD1 . TYR A 1 72  ? 148.077 135.339 140.594 1.00 79.26  ? 242 TYR A CD1 1 
ATOM 573  C CD2 . TYR A 1 72  ? 149.814 133.706 140.428 1.00 79.70  ? 242 TYR A CD2 1 
ATOM 574  C CE1 . TYR A 1 72  ? 147.713 134.836 141.835 1.00 79.37  ? 242 TYR A CE1 1 
ATOM 575  C CE2 . TYR A 1 72  ? 149.459 133.194 141.675 1.00 79.84  ? 242 TYR A CE2 1 
ATOM 576  C CZ  . TYR A 1 72  ? 148.407 133.768 142.370 1.00 79.63  ? 242 TYR A CZ  1 
ATOM 577  O OH  . TYR A 1 72  ? 148.047 133.275 143.603 1.00 79.82  ? 242 TYR A OH  1 
ATOM 578  N N   . ASN A 1 73  ? 149.818 134.801 135.348 1.00 80.06  ? 243 ASN A N   1 
ATOM 579  C CA  . ASN A 1 73  ? 150.268 135.279 134.040 1.00 79.94  ? 243 ASN A CA  1 
ATOM 580  C C   . ASN A 1 73  ? 149.261 135.080 132.905 1.00 80.04  ? 243 ASN A C   1 
ATOM 581  O O   . ASN A 1 73  ? 149.611 135.236 131.736 1.00 79.99  ? 243 ASN A O   1 
ATOM 582  C CB  . ASN A 1 73  ? 151.646 134.702 133.678 1.00 79.80  ? 243 ASN A CB  1 
ATOM 583  C CG  . ASN A 1 73  ? 151.587 133.258 133.198 1.00 79.62  ? 243 ASN A CG  1 
ATOM 584  O OD1 . ASN A 1 73  ? 150.629 132.528 133.458 1.00 79.52  ? 243 ASN A OD1 1 
ATOM 585  N ND2 . ASN A 1 73  ? 152.632 132.841 132.500 1.00 78.76  ? 243 ASN A ND2 1 
ATOM 586  N N   . SER A 1 74  ? 148.019 134.747 133.259 1.00 80.23  ? 244 SER A N   1 
ATOM 587  C CA  . SER A 1 74  ? 146.952 134.537 132.268 1.00 80.39  ? 244 SER A CA  1 
ATOM 588  C C   . SER A 1 74  ? 146.117 135.800 132.024 1.00 80.20  ? 244 SER A C   1 
ATOM 589  O O   . SER A 1 74  ? 145.671 136.035 130.897 1.00 80.38  ? 244 SER A O   1 
ATOM 590  C CB  . SER A 1 74  ? 146.055 133.343 132.638 1.00 80.56  ? 244 SER A CB  1 
ATOM 591  O OG  . SER A 1 74  ? 145.183 133.662 133.715 1.00 80.83  ? 244 SER A OG  1 
ATOM 592  N N   . ASP A 1 75  ? 145.901 136.602 133.069 1.00 79.82  ? 245 ASP A N   1 
ATOM 593  C CA  . ASP A 1 75  ? 145.137 137.843 132.925 1.00 79.47  ? 245 ASP A CA  1 
ATOM 594  C C   . ASP A 1 75  ? 146.136 138.953 132.603 1.00 78.57  ? 245 ASP A C   1 
ATOM 595  O O   . ASP A 1 75  ? 146.620 139.658 133.499 1.00 78.19  ? 245 ASP A O   1 
ATOM 596  C CB  . ASP A 1 75  ? 144.320 138.173 134.192 1.00 80.07  ? 245 ASP A CB  1 
ATOM 597  C CG  . ASP A 1 75  ? 143.191 139.198 133.931 1.00 80.86  ? 245 ASP A CG  1 
ATOM 598  O OD1 . ASP A 1 75  ? 143.309 140.058 133.022 1.00 80.88  ? 245 ASP A OD1 1 
ATOM 599  O OD2 . ASP A 1 75  ? 142.173 139.145 134.656 1.00 82.10  ? 245 ASP A OD2 1 
ATOM 600  N N   . THR A 1 76  ? 146.447 139.083 131.316 1.00 77.52  ? 246 THR A N   1 
ATOM 601  C CA  . THR A 1 76  ? 147.407 140.078 130.833 1.00 76.52  ? 246 THR A CA  1 
ATOM 602  C C   . THR A 1 76  ? 146.999 141.541 131.039 1.00 75.99  ? 246 THR A C   1 
ATOM 603  O O   . THR A 1 76  ? 147.866 142.384 131.262 1.00 75.83  ? 246 THR A O   1 
ATOM 604  C CB  . THR A 1 76  ? 147.781 139.850 129.351 1.00 76.40  ? 246 THR A CB  1 
ATOM 605  O OG1 . THR A 1 76  ? 146.604 139.939 128.549 1.00 76.27  ? 246 THR A OG1 1 
ATOM 606  C CG2 . THR A 1 76  ? 148.423 138.486 129.157 1.00 75.76  ? 246 THR A CG2 1 
ATOM 607  N N   . VAL A 1 77  ? 145.703 141.852 130.962 1.00 75.30  ? 247 VAL A N   1 
ATOM 608  C CA  . VAL A 1 77  ? 145.265 143.244 131.158 1.00 74.52  ? 247 VAL A CA  1 
ATOM 609  C C   . VAL A 1 77  ? 145.438 143.649 132.605 1.00 73.91  ? 247 VAL A C   1 
ATOM 610  O O   . VAL A 1 77  ? 145.928 144.745 132.886 1.00 74.05  ? 247 VAL A O   1 
ATOM 611  C CB  . VAL A 1 77  ? 143.822 143.557 130.640 1.00 74.70  ? 247 VAL A CB  1 
ATOM 612  C CG1 . VAL A 1 77  ? 143.692 143.193 129.161 1.00 73.83  ? 247 VAL A CG1 1 
ATOM 613  C CG2 . VAL A 1 77  ? 142.744 142.864 131.474 1.00 75.26  ? 247 VAL A CG2 1 
ATOM 614  N N   . LEU A 1 78  ? 145.078 142.752 133.523 1.00 73.16  ? 248 LEU A N   1 
ATOM 615  C CA  . LEU A 1 78  ? 145.219 143.031 134.946 1.00 72.20  ? 248 LEU A CA  1 
ATOM 616  C C   . LEU A 1 78  ? 146.687 143.252 135.287 1.00 72.09  ? 248 LEU A C   1 
ATOM 617  O O   . LEU A 1 78  ? 147.016 144.178 136.037 1.00 72.09  ? 248 LEU A O   1 
ATOM 618  C CB  . LEU A 1 78  ? 144.614 141.927 135.816 1.00 71.91  ? 248 LEU A CB  1 
ATOM 619  C CG  . LEU A 1 78  ? 144.623 142.213 137.326 1.00 71.71  ? 248 LEU A CG  1 
ATOM 620  C CD1 . LEU A 1 78  ? 143.959 143.542 137.650 1.00 70.23  ? 248 LEU A CD1 1 
ATOM 621  C CD2 . LEU A 1 78  ? 143.969 141.104 138.114 1.00 71.85  ? 248 LEU A CD2 1 
ATOM 622  N N   . VAL A 1 79  ? 147.569 142.430 134.716 1.00 71.68  ? 249 VAL A N   1 
ATOM 623  C CA  . VAL A 1 79  ? 149.007 142.570 134.961 1.00 71.32  ? 249 VAL A CA  1 
ATOM 624  C C   . VAL A 1 79  ? 149.487 143.922 134.436 1.00 71.22  ? 249 VAL A C   1 
ATOM 625  O O   . VAL A 1 79  ? 150.132 144.679 135.161 1.00 71.49  ? 249 VAL A O   1 
ATOM 626  C CB  . VAL A 1 79  ? 149.831 141.423 134.354 1.00 71.15  ? 249 VAL A CB  1 
ATOM 627  C CG1 . VAL A 1 79  ? 151.310 141.694 134.520 1.00 70.88  ? 249 VAL A CG1 1 
ATOM 628  C CG2 . VAL A 1 79  ? 149.474 140.110 135.020 1.00 71.05  ? 249 VAL A CG2 1 
ATOM 629  N N   . HIS A 1 80  ? 149.132 144.228 133.194 1.00 70.98  ? 250 HIS A N   1 
ATOM 630  C CA  . HIS A 1 80  ? 149.495 145.488 132.566 1.00 71.05  ? 250 HIS A CA  1 
ATOM 631  C C   . HIS A 1 80  ? 148.961 146.666 133.376 1.00 70.99  ? 250 HIS A C   1 
ATOM 632  O O   . HIS A 1 80  ? 149.652 147.672 133.533 1.00 71.10  ? 250 HIS A O   1 
ATOM 633  C CB  . HIS A 1 80  ? 148.933 145.554 131.151 1.00 71.02  ? 250 HIS A CB  1 
ATOM 634  C CG  . HIS A 1 80  ? 149.666 146.497 130.245 1.00 72.16  ? 250 HIS A CG  1 
ATOM 635  N ND1 . HIS A 1 80  ? 150.425 147.549 130.713 1.00 73.75  ? 250 HIS A ND1 1 
ATOM 636  C CD2 . HIS A 1 80  ? 149.729 146.561 128.893 1.00 72.49  ? 250 HIS A CD2 1 
ATOM 637  C CE1 . HIS A 1 80  ? 150.931 148.213 129.687 1.00 74.02  ? 250 HIS A CE1 1 
ATOM 638  N NE2 . HIS A 1 80  ? 150.527 147.632 128.573 1.00 72.45  ? 250 HIS A NE2 1 
ATOM 639  N N   . ARG A 1 81  ? 147.736 146.547 133.885 1.00 70.86  ? 251 ARG A N   1 
ATOM 640  C CA  . ARG A 1 81  ? 147.140 147.625 134.670 1.00 70.70  ? 251 ARG A CA  1 
ATOM 641  C C   . ARG A 1 81  ? 147.957 147.863 135.934 1.00 70.82  ? 251 ARG A C   1 
ATOM 642  O O   . ARG A 1 81  ? 148.326 149.006 136.246 1.00 71.48  ? 251 ARG A O   1 
ATOM 643  C CB  . ARG A 1 81  ? 145.691 147.314 135.035 1.00 70.66  ? 251 ARG A CB  1 
ATOM 644  C CG  . ARG A 1 81  ? 144.696 147.502 133.909 1.00 70.63  ? 251 ARG A CG  1 
ATOM 645  C CD  . ARG A 1 81  ? 143.300 147.096 134.360 1.00 72.00  ? 251 ARG A CD  1 
ATOM 646  N NE  . ARG A 1 81  ? 142.768 147.998 135.390 1.00 74.39  ? 251 ARG A NE  1 
ATOM 647  C CZ  . ARG A 1 81  ? 141.708 147.738 136.158 1.00 74.25  ? 251 ARG A CZ  1 
ATOM 648  N NH1 . ARG A 1 81  ? 141.052 146.593 136.039 1.00 73.23  ? 251 ARG A NH1 1 
ATOM 649  N NH2 . ARG A 1 81  ? 141.306 148.629 137.056 1.00 74.80  ? 251 ARG A NH2 1 
ATOM 650  N N   . VAL A 1 82  ? 148.255 146.781 136.650 1.00 70.28  ? 252 VAL A N   1 
ATOM 651  C CA  . VAL A 1 82  ? 149.027 146.871 137.873 1.00 69.43  ? 252 VAL A CA  1 
ATOM 652  C C   . VAL A 1 82  ? 150.388 147.469 137.577 1.00 69.58  ? 252 VAL A C   1 
ATOM 653  O O   . VAL A 1 82  ? 150.836 148.376 138.284 1.00 69.80  ? 252 VAL A O   1 
ATOM 654  C CB  . VAL A 1 82  ? 149.171 145.503 138.563 1.00 69.18  ? 252 VAL A CB  1 
ATOM 655  C CG1 . VAL A 1 82  ? 150.110 145.598 139.762 1.00 68.56  ? 252 VAL A CG1 1 
ATOM 656  C CG2 . VAL A 1 82  ? 147.821 145.010 139.006 1.00 68.09  ? 252 VAL A CG2 1 
ATOM 657  N N   . HIS A 1 83  ? 151.036 146.982 136.523 1.00 69.49  ? 253 HIS A N   1 
ATOM 658  C CA  . HIS A 1 83  ? 152.353 147.492 136.166 1.00 69.66  ? 253 HIS A CA  1 
ATOM 659  C C   . HIS A 1 83  ? 152.340 148.999 135.910 1.00 69.90  ? 253 HIS A C   1 
ATOM 660  O O   . HIS A 1 83  ? 153.132 149.736 136.506 1.00 70.36  ? 253 HIS A O   1 
ATOM 661  C CB  . HIS A 1 83  ? 152.947 146.745 134.979 1.00 69.42  ? 253 HIS A CB  1 
ATOM 662  C CG  . HIS A 1 83  ? 154.306 147.235 134.592 1.00 69.91  ? 253 HIS A CG  1 
ATOM 663  N ND1 . HIS A 1 83  ? 154.499 148.290 133.726 1.00 70.48  ? 253 HIS A ND1 1 
ATOM 664  C CD2 . HIS A 1 83  ? 155.542 146.824 134.964 1.00 70.64  ? 253 HIS A CD2 1 
ATOM 665  C CE1 . HIS A 1 83  ? 155.794 148.504 133.573 1.00 70.53  ? 253 HIS A CE1 1 
ATOM 666  N NE2 . HIS A 1 83  ? 156.448 147.622 134.309 1.00 70.74  ? 253 HIS A NE2 1 
ATOM 667  N N   . SER A 1 84  ? 151.434 149.460 135.054 1.00 69.68  ? 254 SER A N   1 
ATOM 668  C CA  . SER A 1 84  ? 151.358 150.885 134.747 1.00 69.99  ? 254 SER A CA  1 
ATOM 669  C C   . SER A 1 84  ? 151.056 151.703 135.979 1.00 69.88  ? 254 SER A C   1 
ATOM 670  O O   . SER A 1 84  ? 151.593 152.796 136.150 1.00 70.18  ? 254 SER A O   1 
ATOM 671  C CB  . SER A 1 84  ? 150.346 151.162 133.639 1.00 69.90  ? 254 SER A CB  1 
ATOM 672  O OG  . SER A 1 84  ? 150.791 150.528 132.449 1.00 71.35  ? 254 SER A OG  1 
ATOM 673  N N   . TYR A 1 85  ? 150.218 151.148 136.844 1.00 69.56  ? 255 TYR A N   1 
ATOM 674  C CA  . TYR A 1 85  ? 149.849 151.802 138.070 1.00 69.32  ? 255 TYR A CA  1 
ATOM 675  C C   . TYR A 1 85  ? 151.080 152.027 138.961 1.00 69.42  ? 255 TYR A C   1 
ATOM 676  O O   . TYR A 1 85  ? 151.316 153.138 139.468 1.00 69.17  ? 255 TYR A O   1 
ATOM 677  C CB  . TYR A 1 85  ? 148.799 150.967 138.807 1.00 69.36  ? 255 TYR A CB  1 
ATOM 678  C CG  . TYR A 1 85  ? 148.681 151.366 140.237 1.00 69.61  ? 255 TYR A CG  1 
ATOM 679  C CD1 . TYR A 1 85  ? 147.992 152.517 140.583 1.00 70.00  ? 255 TYR A CD1 1 
ATOM 680  C CD2 . TYR A 1 85  ? 149.303 150.629 141.252 1.00 69.39  ? 255 TYR A CD2 1 
ATOM 681  C CE1 . TYR A 1 85  ? 147.907 152.924 141.893 1.00 69.32  ? 255 TYR A CE1 1 
ATOM 682  C CE2 . TYR A 1 85  ? 149.214 151.030 142.567 1.00 68.49  ? 255 TYR A CE2 1 
ATOM 683  C CZ  . TYR A 1 85  ? 148.515 152.182 142.871 1.00 68.74  ? 255 TYR A CZ  1 
ATOM 684  O OH  . TYR A 1 85  ? 148.398 152.622 144.164 1.00 71.25  ? 255 TYR A OH  1 
ATOM 685  N N   . LEU A 1 86  ? 151.860 150.967 139.165 1.00 69.42  ? 256 LEU A N   1 
ATOM 686  C CA  . LEU A 1 86  ? 153.050 151.067 140.008 1.00 69.43  ? 256 LEU A CA  1 
ATOM 687  C C   . LEU A 1 86  ? 154.076 152.010 139.391 1.00 69.75  ? 256 LEU A C   1 
ATOM 688  O O   . LEU A 1 86  ? 154.682 152.835 140.080 1.00 69.77  ? 256 LEU A O   1 
ATOM 689  C CB  . LEU A 1 86  ? 153.672 149.693 140.231 1.00 68.99  ? 256 LEU A CB  1 
ATOM 690  C CG  . LEU A 1 86  ? 152.807 148.689 140.988 1.00 68.60  ? 256 LEU A CG  1 
ATOM 691  C CD1 . LEU A 1 86  ? 153.444 147.328 140.870 1.00 67.84  ? 256 LEU A CD1 1 
ATOM 692  C CD2 . LEU A 1 86  ? 152.589 149.069 142.458 1.00 66.83  ? 256 LEU A CD2 1 
ATOM 693  N N   . GLU A 1 87  ? 154.252 151.882 138.085 1.00 69.62  ? 257 GLU A N   1 
ATOM 694  C CA  . GLU A 1 87  ? 155.193 152.701 137.366 1.00 70.14  ? 257 GLU A CA  1 
ATOM 695  C C   . GLU A 1 87  ? 154.818 154.177 137.487 1.00 70.04  ? 257 GLU A C   1 
ATOM 696  O O   . GLU A 1 87  ? 155.663 155.027 137.783 1.00 69.94  ? 257 GLU A O   1 
ATOM 697  C CB  . GLU A 1 87  ? 155.249 152.246 135.899 1.00 70.13  ? 257 GLU A CB  1 
ATOM 698  C CG  . GLU A 1 87  ? 156.102 153.104 135.002 1.00 72.09  ? 257 GLU A CG  1 
ATOM 699  C CD  . GLU A 1 87  ? 156.445 152.416 133.702 1.00 75.63  ? 257 GLU A CD  1 
ATOM 700  O OE1 . GLU A 1 87  ? 155.534 152.207 132.864 1.00 76.90  ? 257 GLU A OE1 1 
ATOM 701  O OE2 . GLU A 1 87  ? 157.637 152.089 133.514 1.00 77.21  ? 257 GLU A OE2 1 
ATOM 702  N N   . ARG A 1 88  ? 153.540 154.458 137.268 1.00 70.22  ? 258 ARG A N   1 
ATOM 703  C CA  . ARG A 1 88  ? 153.011 155.814 137.305 1.00 70.50  ? 258 ARG A CA  1 
ATOM 704  C C   . ARG A 1 88  ? 153.163 156.450 138.671 1.00 70.88  ? 258 ARG A C   1 
ATOM 705  O O   . ARG A 1 88  ? 153.479 157.628 138.770 1.00 71.07  ? 258 ARG A O   1 
ATOM 706  C CB  . ARG A 1 88  ? 151.546 155.814 136.840 1.00 70.19  ? 258 ARG A CB  1 
ATOM 707  C CG  . ARG A 1 88  ? 150.854 157.171 136.694 1.00 70.37  ? 258 ARG A CG  1 
ATOM 708  C CD  . ARG A 1 88  ? 151.627 158.197 135.877 1.00 70.84  ? 258 ARG A CD  1 
ATOM 709  N NE  . ARG A 1 88  ? 151.795 157.911 134.441 1.00 70.02  ? 258 ARG A NE  1 
ATOM 710  C CZ  . ARG A 1 88  ? 150.886 158.180 133.501 1.00 69.15  ? 258 ARG A CZ  1 
ATOM 711  N NH1 . ARG A 1 88  ? 149.700 158.688 133.819 1.00 68.69  ? 258 ARG A NH1 1 
ATOM 712  N NH2 . ARG A 1 88  ? 151.148 157.920 132.231 1.00 68.06  ? 258 ARG A NH2 1 
ATOM 713  N N   . HIS A 1 89  ? 152.956 155.665 139.722 1.00 71.20  ? 259 HIS A N   1 
ATOM 714  C CA  . HIS A 1 89  ? 153.064 156.188 141.074 1.00 71.74  ? 259 HIS A CA  1 
ATOM 715  C C   . HIS A 1 89  ? 154.475 156.131 141.661 1.00 71.64  ? 259 HIS A C   1 
ATOM 716  O O   . HIS A 1 89  ? 154.680 156.455 142.825 1.00 71.82  ? 259 HIS A O   1 
ATOM 717  C CB  . HIS A 1 89  ? 152.033 155.527 141.984 1.00 71.82  ? 259 HIS A CB  1 
ATOM 718  C CG  . HIS A 1 89  ? 150.627 155.877 141.619 1.00 73.90  ? 259 HIS A CG  1 
ATOM 719  N ND1 . HIS A 1 89  ? 149.948 155.251 140.594 1.00 75.75  ? 259 HIS A ND1 1 
ATOM 720  C CD2 . HIS A 1 89  ? 149.784 156.816 142.111 1.00 75.36  ? 259 HIS A CD2 1 
ATOM 721  C CE1 . HIS A 1 89  ? 148.742 155.782 140.479 1.00 76.28  ? 259 HIS A CE1 1 
ATOM 722  N NE2 . HIS A 1 89  ? 148.620 156.739 141.384 1.00 76.64  ? 259 HIS A NE2 1 
ATOM 723  N N   . GLY A 1 90  ? 155.444 155.746 140.842 1.00 71.35  ? 260 GLY A N   1 
ATOM 724  C CA  . GLY A 1 90  ? 156.828 155.691 141.277 1.00 70.77  ? 260 GLY A CA  1 
ATOM 725  C C   . GLY A 1 90  ? 157.225 154.575 142.206 1.00 70.75  ? 260 GLY A C   1 
ATOM 726  O O   . GLY A 1 90  ? 158.295 154.637 142.801 1.00 71.71  ? 260 GLY A O   1 
ATOM 727  N N   . LEU A 1 91  ? 156.393 153.546 142.334 1.00 70.40  ? 261 LEU A N   1 
ATOM 728  C CA  . LEU A 1 91  ? 156.709 152.392 143.202 1.00 69.17  ? 261 LEU A CA  1 
ATOM 729  C C   . LEU A 1 91  ? 157.722 151.462 142.531 1.00 68.95  ? 261 LEU A C   1 
ATOM 730  O O   . LEU A 1 91  ? 158.401 150.688 143.184 1.00 69.16  ? 261 LEU A O   1 
ATOM 731  C CB  . LEU A 1 91  ? 155.437 151.653 143.605 1.00 68.83  ? 261 LEU A CB  1 
ATOM 732  C CG  . LEU A 1 91  ? 154.632 152.466 144.627 1.00 67.95  ? 261 LEU A CG  1 
ATOM 733  C CD1 . LEU A 1 91  ? 153.175 152.044 144.685 1.00 66.88  ? 261 LEU A CD1 1 
ATOM 734  C CD2 . LEU A 1 91  ? 155.279 152.387 145.994 1.00 66.15  ? 261 LEU A CD2 1 
ATOM 735  N N   . ILE A 1 92  ? 157.822 151.548 141.211 1.00 68.68  ? 262 ILE A N   1 
ATOM 736  C CA  . ILE A 1 92  ? 158.801 150.766 140.447 1.00 68.18  ? 262 ILE A CA  1 
ATOM 737  C C   . ILE A 1 92  ? 159.365 151.756 139.434 1.00 68.16  ? 262 ILE A C   1 
ATOM 738  O O   . ILE A 1 92  ? 158.740 152.786 139.157 1.00 68.48  ? 262 ILE A O   1 
ATOM 739  C CB  . ILE A 1 92  ? 158.207 149.516 139.704 1.00 68.11  ? 262 ILE A CB  1 
ATOM 740  C CG1 . ILE A 1 92  ? 157.143 149.923 138.677 1.00 67.25  ? 262 ILE A CG1 1 
ATOM 741  C CG2 . ILE A 1 92  ? 157.650 148.499 140.684 1.00 68.10  ? 262 ILE A CG2 1 
ATOM 742  C CD1 . ILE A 1 92  ? 156.759 148.825 137.728 1.00 67.68  ? 262 ILE A CD1 1 
ATOM 743  N N   . ASN A 1 93  ? 160.542 151.462 138.899 1.00 67.51  ? 263 ASN A N   1 
ATOM 744  C CA  . ASN A 1 93  ? 161.160 152.322 137.897 1.00 66.89  ? 263 ASN A CA  1 
ATOM 745  C C   . ASN A 1 93  ? 161.365 153.779 138.288 1.00 66.43  ? 263 ASN A C   1 
ATOM 746  O O   . ASN A 1 93  ? 161.116 154.684 137.484 1.00 66.37  ? 263 ASN A O   1 
ATOM 747  C CB  . ASN A 1 93  ? 160.395 152.225 136.577 1.00 66.76  ? 263 ASN A CB  1 
ATOM 748  C CG  . ASN A 1 93  ? 160.409 150.835 136.009 1.00 67.37  ? 263 ASN A CG  1 
ATOM 749  O OD1 . ASN A 1 93  ? 161.343 150.061 136.245 1.00 68.60  ? 263 ASN A OD1 1 
ATOM 750  N ND2 . ASN A 1 93  ? 159.375 150.495 135.263 1.00 67.02  ? 263 ASN A ND2 1 
ATOM 751  N N   . PHE A 1 94  ? 161.833 153.990 139.517 1.00 65.86  ? 264 PHE A N   1 
ATOM 752  C CA  . PHE A 1 94  ? 162.132 155.330 140.019 1.00 65.13  ? 264 PHE A CA  1 
ATOM 753  C C   . PHE A 1 94  ? 163.630 155.379 140.334 1.00 64.78  ? 264 PHE A C   1 
ATOM 754  O O   . PHE A 1 94  ? 164.262 154.337 140.534 1.00 64.33  ? 264 PHE A O   1 
ATOM 755  C CB  . PHE A 1 94  ? 161.274 155.691 141.236 1.00 64.99  ? 264 PHE A CB  1 
ATOM 756  C CG  . PHE A 1 94  ? 161.636 154.948 142.492 1.00 65.31  ? 264 PHE A CG  1 
ATOM 757  C CD1 . PHE A 1 94  ? 162.585 155.457 143.373 1.00 65.29  ? 264 PHE A CD1 1 
ATOM 758  C CD2 . PHE A 1 94  ? 161.008 153.749 142.814 1.00 66.28  ? 264 PHE A CD2 1 
ATOM 759  C CE1 . PHE A 1 94  ? 162.925 154.763 144.543 1.00 65.15  ? 264 PHE A CE1 1 
ATOM 760  C CE2 . PHE A 1 94  ? 161.338 153.049 143.993 1.00 66.73  ? 264 PHE A CE2 1 
ATOM 761  C CZ  . PHE A 1 94  ? 162.296 153.564 144.853 1.00 65.44  ? 264 PHE A CZ  1 
ATOM 762  N N   . GLY A 1 95  ? 164.189 156.584 140.362 1.00 64.61  ? 265 GLY A N   1 
ATOM 763  C CA  . GLY A 1 95  ? 165.597 156.779 140.643 1.00 64.50  ? 265 GLY A CA  1 
ATOM 764  C C   . GLY A 1 95  ? 166.440 156.763 139.387 1.00 64.79  ? 265 GLY A C   1 
ATOM 765  O O   . GLY A 1 95  ? 166.077 157.388 138.395 1.00 65.18  ? 265 GLY A O   1 
ATOM 766  N N   . ILE A 1 96  ? 167.571 156.057 139.440 1.00 64.98  ? 266 ILE A N   1 
ATOM 767  C CA  . ILE A 1 96  ? 168.507 155.953 138.321 1.00 65.21  ? 266 ILE A CA  1 
ATOM 768  C C   . ILE A 1 96  ? 168.704 154.502 137.966 1.00 65.66  ? 266 ILE A C   1 
ATOM 769  O O   . ILE A 1 96  ? 169.257 153.741 138.750 1.00 65.67  ? 266 ILE A O   1 
ATOM 770  C CB  . ILE A 1 96  ? 169.889 156.534 138.677 1.00 65.10  ? 266 ILE A CB  1 
ATOM 771  C CG1 . ILE A 1 96  ? 169.730 157.903 139.327 1.00 65.13  ? 266 ILE A CG1 1 
ATOM 772  C CG2 . ILE A 1 96  ? 170.779 156.632 137.437 1.00 64.66  ? 266 ILE A CG2 1 
ATOM 773  C CD1 . ILE A 1 96  ? 170.879 158.306 140.175 1.00 65.75  ? 266 ILE A CD1 1 
ATOM 774  N N   . TYR A 1 97  ? 168.269 154.127 136.774 1.00 66.39  ? 267 TYR A N   1 
ATOM 775  C CA  . TYR A 1 97  ? 168.391 152.759 136.299 1.00 67.27  ? 267 TYR A CA  1 
ATOM 776  C C   . TYR A 1 97  ? 168.635 152.758 134.805 1.00 68.58  ? 267 TYR A C   1 
ATOM 777  O O   . TYR A 1 97  ? 168.345 153.745 134.127 1.00 68.61  ? 267 TYR A O   1 
ATOM 778  C CB  . TYR A 1 97  ? 167.100 151.998 136.594 1.00 66.76  ? 267 TYR A CB  1 
ATOM 779  C CG  . TYR A 1 97  ? 165.854 152.743 136.165 1.00 66.54  ? 267 TYR A CG  1 
ATOM 780  C CD1 . TYR A 1 97  ? 165.234 153.653 137.023 1.00 65.74  ? 267 TYR A CD1 1 
ATOM 781  C CD2 . TYR A 1 97  ? 165.299 152.547 134.893 1.00 66.18  ? 267 TYR A CD2 1 
ATOM 782  C CE1 . TYR A 1 97  ? 164.099 154.347 136.638 1.00 65.24  ? 267 TYR A CE1 1 
ATOM 783  C CE2 . TYR A 1 97  ? 164.156 153.238 134.495 1.00 65.69  ? 267 TYR A CE2 1 
ATOM 784  C CZ  . TYR A 1 97  ? 163.559 154.133 135.374 1.00 66.54  ? 267 TYR A CZ  1 
ATOM 785  O OH  . TYR A 1 97  ? 162.429 154.823 134.990 1.00 66.44  ? 267 TYR A OH  1 
ATOM 786  N N   . LYS A 1 98  ? 169.150 151.648 134.282 1.00 70.24  ? 268 LYS A N   1 
ATOM 787  C CA  . LYS A 1 98  ? 169.384 151.552 132.845 1.00 72.13  ? 268 LYS A CA  1 
ATOM 788  C C   . LYS A 1 98  ? 168.017 151.395 132.194 1.00 72.88  ? 268 LYS A C   1 
ATOM 789  O O   . LYS A 1 98  ? 167.202 150.572 132.614 1.00 72.82  ? 268 LYS A O   1 
ATOM 790  C CB  . LYS A 1 98  ? 170.325 150.399 132.483 1.00 72.56  ? 268 LYS A CB  1 
ATOM 791  C CG  . LYS A 1 98  ? 171.728 150.519 133.100 1.00 73.86  ? 268 LYS A CG  1 
ATOM 792  C CD  . LYS A 1 98  ? 172.766 149.686 132.328 1.00 75.79  ? 268 LYS A CD  1 
ATOM 793  C CE  . LYS A 1 98  ? 174.078 149.533 133.118 1.00 75.21  ? 268 LYS A CE  1 
ATOM 794  N NZ  . LYS A 1 98  ? 175.137 148.887 132.279 1.00 76.08  ? 268 LYS A NZ  1 
ATOM 795  N N   . ARG A 1 99  ? 167.759 152.228 131.199 1.00 73.97  ? 269 ARG A N   1 
ATOM 796  C CA  . ARG A 1 99  ? 166.489 152.218 130.504 1.00 75.22  ? 269 ARG A CA  1 
ATOM 797  C C   . ARG A 1 99  ? 166.506 151.179 129.387 1.00 75.76  ? 269 ARG A C   1 
ATOM 798  O O   . ARG A 1 99  ? 167.451 151.126 128.607 1.00 75.70  ? 269 ARG A O   1 
ATOM 799  C CB  . ARG A 1 99  ? 166.231 153.618 129.951 1.00 75.35  ? 269 ARG A CB  1 
ATOM 800  C CG  . ARG A 1 99  ? 164.804 153.905 129.544 1.00 77.29  ? 269 ARG A CG  1 
ATOM 801  C CD  . ARG A 1 99  ? 164.590 155.401 129.337 1.00 80.54  ? 269 ARG A CD  1 
ATOM 802  N NE  . ARG A 1 99  ? 164.894 156.148 130.562 1.00 83.99  ? 269 ARG A NE  1 
ATOM 803  C CZ  . ARG A 1 99  ? 164.041 156.326 131.579 1.00 85.07  ? 269 ARG A CZ  1 
ATOM 804  N NH1 . ARG A 1 99  ? 162.805 155.824 131.523 1.00 85.00  ? 269 ARG A NH1 1 
ATOM 805  N NH2 . ARG A 1 99  ? 164.428 157.008 132.658 1.00 84.76  ? 269 ARG A NH2 1 
ATOM 806  N N   . ILE A 1 100 ? 165.471 150.343 129.326 1.00 76.71  ? 270 ILE A N   1 
ATOM 807  C CA  . ILE A 1 100 ? 165.377 149.320 128.281 1.00 77.82  ? 270 ILE A CA  1 
ATOM 808  C C   . ILE A 1 100 ? 164.650 149.918 127.071 1.00 78.75  ? 270 ILE A C   1 
ATOM 809  O O   . ILE A 1 100 ? 165.177 149.910 125.951 1.00 78.62  ? 270 ILE A O   1 
ATOM 810  C CB  . ILE A 1 100 ? 164.710 148.004 128.779 1.00 77.73  ? 270 ILE A CB  1 
ATOM 811  C CG1 . ILE A 1 100 ? 165.720 147.184 129.592 1.00 77.64  ? 270 ILE A CG1 1 
ATOM 812  C CG2 . ILE A 1 100 ? 164.170 147.175 127.600 1.00 77.43  ? 270 ILE A CG2 1 
ATOM 813  C CD1 . ILE A 1 100 ? 165.175 145.871 130.148 1.00 77.94  ? 270 ILE A CD1 1 
ATOM 814  N N   . LYS A 1 101 ? 163.452 150.449 127.317 1.00 79.87  ? 271 LYS A N   1 
ATOM 815  C CA  . LYS A 1 101 ? 162.652 151.082 126.279 1.00 81.05  ? 271 LYS A CA  1 
ATOM 816  C C   . LYS A 1 101 ? 163.123 152.526 126.190 1.00 81.47  ? 271 LYS A C   1 
ATOM 817  O O   . LYS A 1 101 ? 163.075 153.242 127.189 1.00 81.51  ? 271 LYS A O   1 
ATOM 818  C CB  . LYS A 1 101 ? 161.161 151.032 126.626 1.00 80.90  ? 271 LYS A CB  1 
ATOM 819  C CG  . LYS A 1 101 ? 160.536 149.639 126.570 1.00 81.62  ? 271 LYS A CG  1 
ATOM 820  C CD  . LYS A 1 101 ? 159.045 149.674 126.956 1.00 81.96  ? 271 LYS A CD  1 
ATOM 821  C CE  . LYS A 1 101 ? 158.327 148.362 126.603 1.00 82.95  ? 271 LYS A CE  1 
ATOM 822  N NZ  . LYS A 1 101 ? 158.406 148.057 125.138 1.00 83.82  ? 271 LYS A NZ  1 
ATOM 823  N N   . PRO A 1 102 ? 163.587 152.964 125.003 1.00 82.21  ? 272 PRO A N   1 
ATOM 824  C CA  . PRO A 1 102 ? 164.109 154.332 124.892 1.00 82.73  ? 272 PRO A CA  1 
ATOM 825  C C   . PRO A 1 102 ? 163.027 155.380 125.198 1.00 83.33  ? 272 PRO A C   1 
ATOM 826  O O   . PRO A 1 102 ? 161.829 155.059 125.169 1.00 83.38  ? 272 PRO A O   1 
ATOM 827  C CB  . PRO A 1 102 ? 164.553 154.419 123.427 1.00 82.57  ? 272 PRO A CB  1 
ATOM 828  C CG  . PRO A 1 102 ? 163.750 153.371 122.722 1.00 82.30  ? 272 PRO A CG  1 
ATOM 829  C CD  . PRO A 1 102 ? 163.627 152.254 123.710 1.00 82.08  ? 272 PRO A CD  1 
ATOM 830  N N   . LEU A 1 103 ? 163.446 156.609 125.510 1.00 83.89  ? 273 LEU A N   1 
ATOM 831  C CA  . LEU A 1 103 ? 162.503 157.689 125.813 1.00 84.32  ? 273 LEU A CA  1 
ATOM 832  C C   . LEU A 1 103 ? 161.828 158.135 124.516 1.00 84.55  ? 273 LEU A C   1 
ATOM 833  O O   . LEU A 1 103 ? 162.498 158.226 123.480 1.00 84.51  ? 273 LEU A O   1 
ATOM 834  C CB  . LEU A 1 103 ? 163.216 158.884 126.459 1.00 84.39  ? 273 LEU A CB  1 
ATOM 835  C CG  . LEU A 1 103 ? 163.846 158.773 127.853 1.00 84.69  ? 273 LEU A CG  1 
ATOM 836  C CD1 . LEU A 1 103 ? 164.698 160.002 128.154 1.00 84.74  ? 273 LEU A CD1 1 
ATOM 837  C CD2 . LEU A 1 103 ? 162.792 158.582 128.931 1.00 85.19  ? 273 LEU A CD2 1 
ATOM 838  N N   . PRO A 1 104 ? 160.502 158.397 124.558 1.00 84.74  ? 274 PRO A N   1 
ATOM 839  C CA  . PRO A 1 104 ? 159.847 158.894 123.345 1.00 84.74  ? 274 PRO A CA  1 
ATOM 840  C C   . PRO A 1 104 ? 160.581 160.130 122.831 1.00 84.68  ? 274 PRO A C   1 
ATOM 841  O O   . PRO A 1 104 ? 160.807 161.081 123.585 1.00 84.68  ? 274 PRO A O   1 
ATOM 842  C CB  . PRO A 1 104 ? 158.420 159.241 123.803 1.00 84.81  ? 274 PRO A CB  1 
ATOM 843  C CG  . PRO A 1 104 ? 158.421 159.138 125.302 1.00 84.84  ? 274 PRO A CG  1 
ATOM 844  C CD  . PRO A 1 104 ? 159.558 158.243 125.683 1.00 84.89  ? 274 PRO A CD  1 
ATOM 845  N N   . THR A 1 105 ? 160.988 160.074 121.569 1.00 84.73  ? 275 THR A N   1 
ATOM 846  C CA  . THR A 1 105 ? 161.726 161.167 120.927 1.00 84.38  ? 275 THR A CA  1 
ATOM 847  C C   . THR A 1 105 ? 160.982 162.523 120.960 1.00 83.54  ? 275 THR A C   1 
ATOM 848  O O   . THR A 1 105 ? 161.581 163.551 121.315 1.00 83.60  ? 275 THR A O   1 
ATOM 849  C CB  . THR A 1 105 ? 162.185 160.778 119.502 1.00 84.60  ? 275 THR A CB  1 
ATOM 850  O OG1 . THR A 1 105 ? 163.099 161.767 119.022 1.00 85.54  ? 275 THR A OG1 1 
ATOM 851  C CG2 . THR A 1 105 ? 160.991 160.619 118.527 1.00 84.68  ? 275 THR A CG2 1 
ATOM 852  N N   . LYS A 1 106 ? 159.691 162.511 120.612 1.00 81.96  ? 276 LYS A N   1 
ATOM 853  C CA  . LYS A 1 106 ? 158.877 163.721 120.659 1.00 80.79  ? 276 LYS A CA  1 
ATOM 854  C C   . LYS A 1 106 ? 158.180 163.691 122.016 1.00 79.21  ? 276 LYS A C   1 
ATOM 855  O O   . LYS A 1 106 ? 157.627 162.666 122.421 1.00 79.21  ? 276 LYS A O   1 
ATOM 856  C CB  . LYS A 1 106 ? 157.886 163.799 119.491 1.00 81.06  ? 276 LYS A CB  1 
ATOM 857  C CG  . LYS A 1 106 ? 158.565 164.136 118.144 1.00 81.70  ? 276 LYS A CG  1 
ATOM 858  C CD  . LYS A 1 106 ? 157.571 164.384 117.006 1.00 81.95  ? 276 LYS A CD  1 
ATOM 859  C CE  . LYS A 1 106 ? 156.879 163.097 116.558 1.00 83.65  ? 276 LYS A CE  1 
ATOM 860  N NZ  . LYS A 1 106 ? 155.897 163.357 115.462 1.00 83.50  ? 276 LYS A NZ  1 
ATOM 861  N N   . LYS A 1 107 ? 158.254 164.802 122.737 1.00 77.23  ? 277 LYS A N   1 
ATOM 862  C CA  . LYS A 1 107 ? 157.684 164.896 124.078 1.00 75.10  ? 277 LYS A CA  1 
ATOM 863  C C   . LYS A 1 107 ? 156.258 165.431 124.133 1.00 73.80  ? 277 LYS A C   1 
ATOM 864  O O   . LYS A 1 107 ? 155.754 165.978 123.151 1.00 73.49  ? 277 LYS A O   1 
ATOM 865  C CB  . LYS A 1 107 ? 158.608 165.740 124.945 1.00 75.13  ? 277 LYS A CB  1 
ATOM 866  C CG  . LYS A 1 107 ? 159.947 165.065 125.249 1.00 75.26  ? 277 LYS A CG  1 
ATOM 867  C CD  . LYS A 1 107 ? 161.080 166.081 125.182 1.00 77.49  ? 277 LYS A CD  1 
ATOM 868  C CE  . LYS A 1 107 ? 162.265 165.730 126.083 1.00 79.00  ? 277 LYS A CE  1 
ATOM 869  N NZ  . LYS A 1 107 ? 162.909 164.439 125.720 1.00 80.28  ? 277 LYS A NZ  1 
ATOM 870  N N   . THR A 1 108 ? 155.611 165.251 125.284 1.00 72.02  ? 278 THR A N   1 
ATOM 871  C CA  . THR A 1 108 ? 154.244 165.713 125.481 1.00 70.60  ? 278 THR A CA  1 
ATOM 872  C C   . THR A 1 108 ? 154.128 166.558 126.737 1.00 69.89  ? 278 THR A C   1 
ATOM 873  O O   . THR A 1 108 ? 154.454 166.106 127.836 1.00 70.52  ? 278 THR A O   1 
ATOM 874  C CB  . THR A 1 108 ? 153.255 164.542 125.551 1.00 70.61  ? 278 THR A CB  1 
ATOM 875  O OG1 . THR A 1 108 ? 153.380 163.747 124.370 1.00 70.36  ? 278 THR A OG1 1 
ATOM 876  C CG2 . THR A 1 108 ? 151.819 165.042 125.659 1.00 69.67  ? 278 THR A CG2 1 
ATOM 877  N N   . GLY A 1 109 ? 153.661 167.790 126.572 1.00 68.96  ? 279 GLY A N   1 
ATOM 878  C CA  . GLY A 1 109 ? 153.492 168.714 127.693 1.00 67.76  ? 279 GLY A CA  1 
ATOM 879  C C   . GLY A 1 109 ? 154.793 169.316 128.181 1.00 67.11  ? 279 GLY A C   1 
ATOM 880  O O   . GLY A 1 109 ? 155.863 168.724 128.020 1.00 67.01  ? 279 GLY A O   1 
ATOM 881  N N   . LYS A 1 110 ? 154.696 170.502 128.782 1.00 66.56  ? 280 LYS A N   1 
ATOM 882  C CA  . LYS A 1 110 ? 155.852 171.211 129.316 1.00 66.40  ? 280 LYS A CA  1 
ATOM 883  C C   . LYS A 1 110 ? 155.639 171.511 130.809 1.00 66.08  ? 280 LYS A C   1 
ATOM 884  O O   . LYS A 1 110 ? 154.597 172.054 131.196 1.00 66.63  ? 280 LYS A O   1 
ATOM 885  C CB  . LYS A 1 110 ? 156.081 172.499 128.532 1.00 66.12  ? 280 LYS A CB  1 
ATOM 886  C CG  . LYS A 1 110 ? 157.165 173.407 129.090 1.00 68.22  ? 280 LYS A CG  1 
ATOM 887  C CD  . LYS A 1 110 ? 158.567 172.925 128.729 1.00 71.41  ? 280 LYS A CD  1 
ATOM 888  C CE  . LYS A 1 110 ? 159.565 173.190 129.865 1.00 72.91  ? 280 LYS A CE  1 
ATOM 889  N NZ  . LYS A 1 110 ? 160.976 173.056 129.410 1.00 72.44  ? 280 LYS A NZ  1 
ATOM 890  N N   . VAL A 1 111 ? 156.616 171.158 131.638 1.00 65.07  ? 281 VAL A N   1 
ATOM 891  C CA  . VAL A 1 111 ? 156.544 171.392 133.083 1.00 64.20  ? 281 VAL A CA  1 
ATOM 892  C C   . VAL A 1 111 ? 157.786 172.111 133.592 1.00 63.97  ? 281 VAL A C   1 
ATOM 893  O O   . VAL A 1 111 ? 158.918 171.728 133.278 1.00 63.83  ? 281 VAL A O   1 
ATOM 894  C CB  . VAL A 1 111 ? 156.448 170.077 133.869 1.00 64.26  ? 281 VAL A CB  1 
ATOM 895  C CG1 . VAL A 1 111 ? 156.344 170.348 135.362 1.00 62.88  ? 281 VAL A CG1 1 
ATOM 896  C CG2 . VAL A 1 111 ? 155.275 169.230 133.379 1.00 64.69  ? 281 VAL A CG2 1 
ATOM 897  N N   . ILE A 1 112 ? 157.575 173.149 134.382 1.00 63.73  ? 282 ILE A N   1 
ATOM 898  C CA  . ILE A 1 112 ? 158.678 173.879 134.968 1.00 63.84  ? 282 ILE A CA  1 
ATOM 899  C C   . ILE A 1 112 ? 158.697 173.454 136.448 1.00 64.55  ? 282 ILE A C   1 
ATOM 900  O O   . ILE A 1 112 ? 157.653 173.439 137.120 1.00 64.51  ? 282 ILE A O   1 
ATOM 901  C CB  . ILE A 1 112 ? 158.493 175.392 134.817 1.00 63.60  ? 282 ILE A CB  1 
ATOM 902  C CG1 . ILE A 1 112 ? 158.828 175.836 133.385 1.00 63.72  ? 282 ILE A CG1 1 
ATOM 903  C CG2 . ILE A 1 112 ? 159.321 176.161 135.843 1.00 64.02  ? 282 ILE A CG2 1 
ATOM 904  C CD1 . ILE A 1 112 ? 160.322 175.823 133.013 1.00 64.20  ? 282 ILE A CD1 1 
ATOM 905  N N   . ILE A 1 113 ? 159.869 173.076 136.939 1.00 64.82  ? 283 ILE A N   1 
ATOM 906  C CA  . ILE A 1 113 ? 160.003 172.659 138.318 1.00 65.38  ? 283 ILE A CA  1 
ATOM 907  C C   . ILE A 1 113 ? 160.833 173.705 139.031 1.00 65.54  ? 283 ILE A C   1 
ATOM 908  O O   . ILE A 1 113 ? 161.944 174.010 138.601 1.00 66.32  ? 283 ILE A O   1 
ATOM 909  C CB  . ILE A 1 113 ? 160.683 171.286 138.432 1.00 65.11  ? 283 ILE A CB  1 
ATOM 910  C CG1 . ILE A 1 113 ? 159.814 170.216 137.762 1.00 66.60  ? 283 ILE A CG1 1 
ATOM 911  C CG2 . ILE A 1 113 ? 160.897 170.918 139.879 1.00 65.25  ? 283 ILE A CG2 1 
ATOM 912  C CD1 . ILE A 1 113 ? 160.313 168.767 137.961 1.00 66.12  ? 283 ILE A CD1 1 
ATOM 913  N N   . ILE A 1 114 ? 160.298 174.268 140.103 1.00 65.25  ? 284 ILE A N   1 
ATOM 914  C CA  . ILE A 1 114 ? 161.037 175.258 140.851 1.00 65.43  ? 284 ILE A CA  1 
ATOM 915  C C   . ILE A 1 114 ? 161.780 174.548 141.957 1.00 65.77  ? 284 ILE A C   1 
ATOM 916  O O   . ILE A 1 114 ? 161.164 173.957 142.839 1.00 65.74  ? 284 ILE A O   1 
ATOM 917  C CB  . ILE A 1 114 ? 160.107 176.292 141.464 1.00 65.63  ? 284 ILE A CB  1 
ATOM 918  C CG1 . ILE A 1 114 ? 159.268 176.931 140.353 1.00 65.95  ? 284 ILE A CG1 1 
ATOM 919  C CG2 . ILE A 1 114 ? 160.915 177.335 142.270 1.00 64.41  ? 284 ILE A CG2 1 
ATOM 920  C CD1 . ILE A 1 114 ? 158.184 177.844 140.849 1.00 66.16  ? 284 ILE A CD1 1 
ATOM 921  N N   . GLY A 1 115 ? 163.104 174.611 141.903 1.00 66.35  ? 285 GLY A N   1 
ATOM 922  C CA  . GLY A 1 115 ? 163.969 173.989 142.907 1.00 66.89  ? 285 GLY A CA  1 
ATOM 923  C C   . GLY A 1 115 ? 164.506 172.635 142.493 1.00 67.52  ? 285 GLY A C   1 
ATOM 924  O O   . GLY A 1 115 ? 163.755 171.802 141.987 1.00 67.83  ? 285 GLY A O   1 
ATOM 925  N N   . SER A 1 116 ? 165.802 172.403 142.697 1.00 67.90  ? 286 SER A N   1 
ATOM 926  C CA  . SER A 1 116 ? 166.382 171.111 142.333 1.00 68.21  ? 286 SER A CA  1 
ATOM 927  C C   . SER A 1 116 ? 166.980 170.393 143.522 1.00 68.20  ? 286 SER A C   1 
ATOM 928  O O   . SER A 1 116 ? 168.136 169.970 143.488 1.00 68.49  ? 286 SER A O   1 
ATOM 929  C CB  . SER A 1 116 ? 167.410 171.215 141.206 1.00 67.90  ? 286 SER A CB  1 
ATOM 930  O OG  . SER A 1 116 ? 168.522 171.957 141.646 1.00 69.44  ? 286 SER A OG  1 
ATOM 931  N N   . GLY A 1 117 ? 166.176 170.253 144.570 1.00 68.45  ? 287 GLY A N   1 
ATOM 932  C CA  . GLY A 1 117 ? 166.570 169.513 145.755 1.00 68.30  ? 287 GLY A CA  1 
ATOM 933  C C   . GLY A 1 117 ? 166.069 168.119 145.411 1.00 68.54  ? 287 GLY A C   1 
ATOM 934  O O   . GLY A 1 117 ? 165.634 167.860 144.280 1.00 69.81  ? 287 GLY A O   1 
ATOM 935  N N   . VAL A 1 118 ? 166.095 167.214 146.365 1.00 68.10  ? 288 VAL A N   1 
ATOM 936  C CA  . VAL A 1 118 ? 165.642 165.861 146.116 1.00 67.58  ? 288 VAL A CA  1 
ATOM 937  C C   . VAL A 1 118 ? 164.202 165.755 145.618 1.00 67.57  ? 288 VAL A C   1 
ATOM 938  O O   . VAL A 1 118 ? 163.927 164.957 144.730 1.00 67.60  ? 288 VAL A O   1 
ATOM 939  C CB  . VAL A 1 118 ? 165.906 164.980 147.342 1.00 67.60  ? 288 VAL A CB  1 
ATOM 940  C CG1 . VAL A 1 118 ? 165.332 163.581 147.151 1.00 66.54  ? 288 VAL A CG1 1 
ATOM 941  C CG2 . VAL A 1 118 ? 167.398 164.924 147.564 1.00 66.92  ? 288 VAL A CG2 1 
ATOM 942  N N   . SER A 1 119 ? 163.278 166.545 146.153 1.00 67.79  ? 289 SER A N   1 
ATOM 943  C CA  . SER A 1 119 ? 161.903 166.425 145.671 1.00 68.24  ? 289 SER A CA  1 
ATOM 944  C C   . SER A 1 119 ? 161.799 166.828 144.201 1.00 68.53  ? 289 SER A C   1 
ATOM 945  O O   . SER A 1 119 ? 161.185 166.125 143.406 1.00 68.79  ? 289 SER A O   1 
ATOM 946  C CB  . SER A 1 119 ? 160.922 167.210 146.521 1.00 68.18  ? 289 SER A CB  1 
ATOM 947  O OG  . SER A 1 119 ? 161.207 168.586 146.462 1.00 69.33  ? 289 SER A OG  1 
ATOM 948  N N   . GLY A 1 120 ? 162.437 167.938 143.841 1.00 68.65  ? 290 GLY A N   1 
ATOM 949  C CA  . GLY A 1 120 ? 162.410 168.422 142.470 1.00 68.67  ? 290 GLY A CA  1 
ATOM 950  C C   . GLY A 1 120 ? 163.050 167.442 141.509 1.00 68.70  ? 290 GLY A C   1 
ATOM 951  O O   . GLY A 1 120 ? 162.477 167.133 140.460 1.00 68.44  ? 290 GLY A O   1 
ATOM 952  N N   . LEU A 1 121 ? 164.234 166.941 141.883 1.00 68.46  ? 291 LEU A N   1 
ATOM 953  C CA  . LEU A 1 121 ? 164.981 165.995 141.048 1.00 67.68  ? 291 LEU A CA  1 
ATOM 954  C C   . LEU A 1 121 ? 164.226 164.698 140.840 1.00 67.92  ? 291 LEU A C   1 
ATOM 955  O O   . LEU A 1 121 ? 164.107 164.220 139.711 1.00 68.84  ? 291 LEU A O   1 
ATOM 956  C CB  . LEU A 1 121 ? 166.358 165.740 141.629 1.00 67.37  ? 291 LEU A CB  1 
ATOM 957  C CG  . LEU A 1 121 ? 167.278 166.958 141.662 1.00 66.51  ? 291 LEU A CG  1 
ATOM 958  C CD1 . LEU A 1 121 ? 168.355 166.763 142.698 1.00 63.57  ? 291 LEU A CD1 1 
ATOM 959  C CD2 . LEU A 1 121 ? 167.898 167.243 140.273 1.00 65.41  ? 291 LEU A CD2 1 
ATOM 960  N N   . ALA A 1 122 ? 163.668 164.149 141.908 1.00 67.59  ? 292 ALA A N   1 
ATOM 961  C CA  . ALA A 1 122 ? 162.898 162.913 141.789 1.00 67.47  ? 292 ALA A CA  1 
ATOM 962  C C   . ALA A 1 122 ? 161.695 163.103 140.863 1.00 67.32  ? 292 ALA A C   1 
ATOM 963  O O   . ALA A 1 122 ? 161.399 162.226 140.050 1.00 67.66  ? 292 ALA A O   1 
ATOM 964  C CB  . ALA A 1 122 ? 162.444 162.425 143.159 1.00 67.29  ? 292 ALA A CB  1 
ATOM 965  N N   . ALA A 1 123 ? 161.001 164.237 140.974 1.00 66.97  ? 293 ALA A N   1 
ATOM 966  C CA  . ALA A 1 123 ? 159.833 164.487 140.116 1.00 67.02  ? 293 ALA A CA  1 
ATOM 967  C C   . ALA A 1 123 ? 160.243 164.630 138.653 1.00 66.94  ? 293 ALA A C   1 
ATOM 968  O O   . ALA A 1 123 ? 159.553 164.135 137.755 1.00 66.81  ? 293 ALA A O   1 
ATOM 969  C CB  . ALA A 1 123 ? 159.089 165.717 140.554 1.00 66.75  ? 293 ALA A CB  1 
ATOM 970  N N   . ALA A 1 124 ? 161.367 165.308 138.429 1.00 66.84  ? 294 ALA A N   1 
ATOM 971  C CA  . ALA A 1 124 ? 161.871 165.533 137.090 1.00 66.73  ? 294 ALA A CA  1 
ATOM 972  C C   . ALA A 1 124 ? 162.209 164.229 136.401 1.00 66.77  ? 294 ALA A C   1 
ATOM 973  O O   . ALA A 1 124 ? 161.826 164.036 135.259 1.00 66.79  ? 294 ALA A O   1 
ATOM 974  C CB  . ALA A 1 124 ? 163.071 166.452 137.113 1.00 66.89  ? 294 ALA A CB  1 
ATOM 975  N N   . ARG A 1 125 ? 162.896 163.320 137.090 1.00 66.96  ? 295 ARG A N   1 
ATOM 976  C CA  . ARG A 1 125 ? 163.248 162.041 136.471 1.00 67.10  ? 295 ARG A CA  1 
ATOM 977  C C   . ARG A 1 125 ? 161.999 161.294 136.057 1.00 67.45  ? 295 ARG A C   1 
ATOM 978  O O   . ARG A 1 125 ? 161.931 160.732 134.941 1.00 68.11  ? 295 ARG A O   1 
ATOM 979  C CB  . ARG A 1 125 ? 164.066 161.171 137.398 1.00 67.21  ? 295 ARG A CB  1 
ATOM 980  C CG  . ARG A 1 125 ? 165.466 161.633 137.584 1.00 67.14  ? 295 ARG A CG  1 
ATOM 981  C CD  . ARG A 1 125 ? 166.377 160.464 137.858 1.00 67.52  ? 295 ARG A CD  1 
ATOM 982  N NE  . ARG A 1 125 ? 167.629 160.754 137.195 1.00 70.10  ? 295 ARG A NE  1 
ATOM 983  C CZ  . ARG A 1 125 ? 168.079 160.131 136.122 1.00 70.80  ? 295 ARG A CZ  1 
ATOM 984  N NH1 . ARG A 1 125 ? 167.422 159.109 135.583 1.00 70.86  ? 295 ARG A NH1 1 
ATOM 985  N NH2 . ARG A 1 125 ? 169.221 160.525 135.605 1.00 73.37  ? 295 ARG A NH2 1 
ATOM 986  N N   . GLN A 1 126 ? 161.000 161.311 136.935 1.00 67.06  ? 296 GLN A N   1 
ATOM 987  C CA  . GLN A 1 126 ? 159.742 160.651 136.640 1.00 67.17  ? 296 GLN A CA  1 
ATOM 988  C C   . GLN A 1 126 ? 159.073 161.252 135.414 1.00 67.15  ? 296 GLN A C   1 
ATOM 989  O O   . GLN A 1 126 ? 158.756 160.533 134.463 1.00 67.00  ? 296 GLN A O   1 
ATOM 990  C CB  . GLN A 1 126 ? 158.813 160.706 137.841 1.00 67.18  ? 296 GLN A CB  1 
ATOM 991  C CG  . GLN A 1 126 ? 159.298 159.873 138.988 1.00 67.38  ? 296 GLN A CG  1 
ATOM 992  C CD  . GLN A 1 126 ? 159.384 158.420 138.616 1.00 68.24  ? 296 GLN A CD  1 
ATOM 993  O OE1 . GLN A 1 126 ? 160.452 157.924 138.268 1.00 68.65  ? 296 GLN A OE1 1 
ATOM 994  N NE2 . GLN A 1 126 ? 158.252 157.732 138.657 1.00 69.15  ? 296 GLN A NE2 1 
ATOM 995  N N   . LEU A 1 127 ? 158.871 162.568 135.431 1.00 67.25  ? 297 LEU A N   1 
ATOM 996  C CA  . LEU A 1 127 ? 158.232 163.258 134.312 1.00 67.23  ? 297 LEU A CA  1 
ATOM 997  C C   . LEU A 1 127 ? 158.978 163.022 132.992 1.00 67.69  ? 297 LEU A C   1 
ATOM 998  O O   . LEU A 1 127 ? 158.362 162.801 131.948 1.00 67.86  ? 297 LEU A O   1 
ATOM 999  C CB  . LEU A 1 127 ? 158.042 164.744 134.624 1.00 66.64  ? 297 LEU A CB  1 
ATOM 1000 C CG  . LEU A 1 127 ? 157.026 164.996 135.738 1.00 65.72  ? 297 LEU A CG  1 
ATOM 1001 C CD1 . LEU A 1 127 ? 157.086 166.425 136.254 1.00 63.64  ? 297 LEU A CD1 1 
ATOM 1002 C CD2 . LEU A 1 127 ? 155.622 164.652 135.283 1.00 64.74  ? 297 LEU A CD2 1 
ATOM 1003 N N   . GLN A 1 128 ? 160.301 163.033 133.036 1.00 68.03  ? 298 GLN A N   1 
ATOM 1004 C CA  . GLN A 1 128 ? 161.065 162.786 131.837 1.00 68.48  ? 298 GLN A CA  1 
ATOM 1005 C C   . GLN A 1 128 ? 160.752 161.369 131.362 1.00 68.63  ? 298 GLN A C   1 
ATOM 1006 O O   . GLN A 1 128 ? 160.495 161.147 130.187 1.00 69.47  ? 298 GLN A O   1 
ATOM 1007 C CB  . GLN A 1 128 ? 162.549 162.959 132.103 1.00 68.52  ? 298 GLN A CB  1 
ATOM 1008 C CG  . GLN A 1 128 ? 163.346 163.234 130.865 1.00 70.61  ? 298 GLN A CG  1 
ATOM 1009 C CD  . GLN A 1 128 ? 164.781 163.618 131.164 1.00 73.71  ? 298 GLN A CD  1 
ATOM 1010 O OE1 . GLN A 1 128 ? 165.574 162.788 131.623 1.00 75.69  ? 298 GLN A OE1 1 
ATOM 1011 N NE2 . GLN A 1 128 ? 165.127 164.884 130.901 1.00 73.31  ? 298 GLN A NE2 1 
ATOM 1012 N N   . SER A 1 129 ? 160.722 160.419 132.289 1.00 69.02  ? 299 SER A N   1 
ATOM 1013 C CA  . SER A 1 129 ? 160.411 159.023 131.969 1.00 68.88  ? 299 SER A CA  1 
ATOM 1014 C C   . SER A 1 129 ? 159.061 158.841 131.347 1.00 68.45  ? 299 SER A C   1 
ATOM 1015 O O   . SER A 1 129 ? 158.869 157.947 130.527 1.00 68.66  ? 299 SER A O   1 
ATOM 1016 C CB  . SER A 1 129 ? 160.410 158.183 133.228 1.00 68.68  ? 299 SER A CB  1 
ATOM 1017 O OG  . SER A 1 129 ? 161.673 157.618 133.404 1.00 70.92  ? 299 SER A OG  1 
ATOM 1018 N N   . PHE A 1 130 ? 158.108 159.652 131.785 1.00 68.11  ? 300 PHE A N   1 
ATOM 1019 C CA  . PHE A 1 130 ? 156.760 159.547 131.278 1.00 68.15  ? 300 PHE A CA  1 
ATOM 1020 C C   . PHE A 1 130 ? 156.610 160.210 129.914 1.00 68.41  ? 300 PHE A C   1 
ATOM 1021 O O   . PHE A 1 130 ? 155.566 160.080 129.290 1.00 69.13  ? 300 PHE A O   1 
ATOM 1022 C CB  . PHE A 1 130 ? 155.750 160.105 132.279 1.00 67.91  ? 300 PHE A CB  1 
ATOM 1023 C CG  . PHE A 1 130 ? 155.791 159.439 133.636 1.00 68.08  ? 300 PHE A CG  1 
ATOM 1024 C CD1 . PHE A 1 130 ? 156.213 158.116 133.782 1.00 68.03  ? 300 PHE A CD1 1 
ATOM 1025 C CD2 . PHE A 1 130 ? 155.381 160.133 134.772 1.00 66.27  ? 300 PHE A CD2 1 
ATOM 1026 C CE1 . PHE A 1 130 ? 156.240 157.507 135.041 1.00 66.81  ? 300 PHE A CE1 1 
ATOM 1027 C CE2 . PHE A 1 130 ? 155.395 159.533 136.022 1.00 65.68  ? 300 PHE A CE2 1 
ATOM 1028 C CZ  . PHE A 1 130 ? 155.826 158.219 136.161 1.00 66.27  ? 300 PHE A CZ  1 
ATOM 1029 N N   . GLY A 1 131 ? 157.647 160.915 129.462 1.00 68.41  ? 301 GLY A N   1 
ATOM 1030 C CA  . GLY A 1 131 ? 157.649 161.577 128.165 1.00 68.28  ? 301 GLY A CA  1 
ATOM 1031 C C   . GLY A 1 131 ? 157.330 163.059 128.124 1.00 68.51  ? 301 GLY A C   1 
ATOM 1032 O O   . GLY A 1 131 ? 156.981 163.589 127.070 1.00 68.65  ? 301 GLY A O   1 
ATOM 1033 N N   . MET A 1 132 ? 157.454 163.745 129.250 1.00 68.78  ? 302 MET A N   1 
ATOM 1034 C CA  . MET A 1 132 ? 157.179 165.177 129.290 1.00 69.10  ? 302 MET A CA  1 
ATOM 1035 C C   . MET A 1 132 ? 158.456 165.997 129.114 1.00 68.72  ? 302 MET A C   1 
ATOM 1036 O O   . MET A 1 132 ? 159.550 165.473 129.290 1.00 69.20  ? 302 MET A O   1 
ATOM 1037 C CB  . MET A 1 132 ? 156.487 165.533 130.603 1.00 68.88  ? 302 MET A CB  1 
ATOM 1038 C CG  . MET A 1 132 ? 155.149 164.834 130.769 1.00 69.57  ? 302 MET A CG  1 
ATOM 1039 S SD  . MET A 1 132 ? 154.112 165.536 132.075 1.00 70.25  ? 302 MET A SD  1 
ATOM 1040 C CE  . MET A 1 132 ? 153.291 166.879 131.197 1.00 69.48  ? 302 MET A CE  1 
ATOM 1041 N N   . ASP A 1 133 ? 158.305 167.271 128.755 1.00 68.43  ? 303 ASP A N   1 
ATOM 1042 C CA  . ASP A 1 133 ? 159.423 168.205 128.578 1.00 68.26  ? 303 ASP A CA  1 
ATOM 1043 C C   . ASP A 1 133 ? 159.597 168.853 129.952 1.00 68.17  ? 303 ASP A C   1 
ATOM 1044 O O   . ASP A 1 133 ? 158.666 169.489 130.449 1.00 68.55  ? 303 ASP A O   1 
ATOM 1045 C CB  . ASP A 1 133 ? 159.031 169.254 127.554 1.00 68.75  ? 303 ASP A CB  1 
ATOM 1046 C CG  . ASP A 1 133 ? 160.195 170.098 127.077 1.00 69.40  ? 303 ASP A CG  1 
ATOM 1047 O OD1 . ASP A 1 133 ? 161.156 170.300 127.837 1.00 71.16  ? 303 ASP A OD1 1 
ATOM 1048 O OD2 . ASP A 1 133 ? 160.120 170.596 125.934 1.00 71.28  ? 303 ASP A OD2 1 
ATOM 1049 N N   . VAL A 1 134 ? 160.763 168.695 130.576 1.00 67.49  ? 304 VAL A N   1 
ATOM 1050 C CA  . VAL A 1 134 ? 160.966 169.239 131.918 1.00 66.77  ? 304 VAL A CA  1 
ATOM 1051 C C   . VAL A 1 134 ? 162.169 170.131 132.104 1.00 66.37  ? 304 VAL A C   1 
ATOM 1052 O O   . VAL A 1 134 ? 163.268 169.774 131.707 1.00 67.04  ? 304 VAL A O   1 
ATOM 1053 C CB  . VAL A 1 134 ? 161.136 168.070 132.926 1.00 66.61  ? 304 VAL A CB  1 
ATOM 1054 C CG1 . VAL A 1 134 ? 161.436 168.574 134.310 1.00 66.86  ? 304 VAL A CG1 1 
ATOM 1055 C CG2 . VAL A 1 134 ? 159.909 167.237 132.970 1.00 66.79  ? 304 VAL A CG2 1 
ATOM 1056 N N   . THR A 1 135 ? 161.976 171.266 132.765 1.00 65.99  ? 305 THR A N   1 
ATOM 1057 C CA  . THR A 1 135 ? 163.080 172.177 133.069 1.00 66.00  ? 305 THR A CA  1 
ATOM 1058 C C   . THR A 1 135 ? 162.994 172.535 134.559 1.00 66.45  ? 305 THR A C   1 
ATOM 1059 O O   . THR A 1 135 ? 161.908 172.801 135.073 1.00 66.86  ? 305 THR A O   1 
ATOM 1060 C CB  . THR A 1 135 ? 163.087 173.450 132.174 1.00 65.81  ? 305 THR A CB  1 
ATOM 1061 O OG1 . THR A 1 135 ? 163.319 173.077 130.812 1.00 66.26  ? 305 THR A OG1 1 
ATOM 1062 C CG2 . THR A 1 135 ? 164.187 174.412 132.570 1.00 65.46  ? 305 THR A CG2 1 
ATOM 1063 N N   . LEU A 1 136 ? 164.136 172.508 135.243 1.00 66.39  ? 306 LEU A N   1 
ATOM 1064 C CA  . LEU A 1 136 ? 164.209 172.863 136.650 1.00 66.24  ? 306 LEU A CA  1 
ATOM 1065 C C   . LEU A 1 136 ? 164.926 174.193 136.763 1.00 66.30  ? 306 LEU A C   1 
ATOM 1066 O O   . LEU A 1 136 ? 165.969 174.405 136.127 1.00 66.42  ? 306 LEU A O   1 
ATOM 1067 C CB  . LEU A 1 136 ? 165.012 171.834 137.459 1.00 66.29  ? 306 LEU A CB  1 
ATOM 1068 C CG  . LEU A 1 136 ? 164.440 170.426 137.633 1.00 66.97  ? 306 LEU A CG  1 
ATOM 1069 C CD1 . LEU A 1 136 ? 164.949 169.480 136.544 1.00 67.61  ? 306 LEU A CD1 1 
ATOM 1070 C CD2 . LEU A 1 136 ? 164.770 169.885 138.995 1.00 66.05  ? 306 LEU A CD2 1 
ATOM 1071 N N   . LEU A 1 137 ? 164.378 175.074 137.591 1.00 66.23  ? 307 LEU A N   1 
ATOM 1072 C CA  . LEU A 1 137 ? 164.972 176.373 137.842 1.00 66.21  ? 307 LEU A CA  1 
ATOM 1073 C C   . LEU A 1 137 ? 165.491 176.302 139.259 1.00 66.72  ? 307 LEU A C   1 
ATOM 1074 O O   . LEU A 1 137 ? 164.727 176.030 140.200 1.00 68.13  ? 307 LEU A O   1 
ATOM 1075 C CB  . LEU A 1 137 ? 163.936 177.465 137.712 1.00 65.70  ? 307 LEU A CB  1 
ATOM 1076 C CG  . LEU A 1 137 ? 163.202 177.454 136.379 1.00 66.49  ? 307 LEU A CG  1 
ATOM 1077 C CD1 . LEU A 1 137 ? 162.195 178.590 136.340 1.00 67.10  ? 307 LEU A CD1 1 
ATOM 1078 C CD2 . LEU A 1 137 ? 164.165 177.545 135.187 1.00 67.39  ? 307 LEU A CD2 1 
ATOM 1079 N N   . GLU A 1 138 ? 166.794 176.492 139.417 1.00 66.47  ? 308 GLU A N   1 
ATOM 1080 C CA  . GLU A 1 138 ? 167.435 176.422 140.728 1.00 65.60  ? 308 GLU A CA  1 
ATOM 1081 C C   . GLU A 1 138 ? 168.210 177.700 141.003 1.00 65.40  ? 308 GLU A C   1 
ATOM 1082 O O   . GLU A 1 138 ? 169.041 178.116 140.198 1.00 65.09  ? 308 GLU A O   1 
ATOM 1083 C CB  . GLU A 1 138 ? 168.365 175.208 140.771 1.00 65.82  ? 308 GLU A CB  1 
ATOM 1084 C CG  . GLU A 1 138 ? 169.303 175.132 141.969 1.00 66.56  ? 308 GLU A CG  1 
ATOM 1085 C CD  . GLU A 1 138 ? 168.552 175.164 143.282 1.00 68.46  ? 308 GLU A CD  1 
ATOM 1086 O OE1 . GLU A 1 138 ? 167.571 174.387 143.436 1.00 67.18  ? 308 GLU A OE1 1 
ATOM 1087 O OE2 . GLU A 1 138 ? 168.946 175.977 144.151 1.00 69.57  ? 308 GLU A OE2 1 
ATOM 1088 N N   . ALA A 1 139 ? 167.921 178.310 142.148 1.00 65.40  ? 309 ALA A N   1 
ATOM 1089 C CA  . ALA A 1 139 ? 168.548 179.554 142.576 1.00 65.61  ? 309 ALA A CA  1 
ATOM 1090 C C   . ALA A 1 139 ? 170.042 179.408 142.847 1.00 66.44  ? 309 ALA A C   1 
ATOM 1091 O O   . ALA A 1 139 ? 170.839 180.237 142.403 1.00 66.85  ? 309 ALA A O   1 
ATOM 1092 C CB  . ALA A 1 139 ? 167.851 180.080 143.802 1.00 65.22  ? 309 ALA A CB  1 
ATOM 1093 N N   . ARG A 1 140 ? 170.416 178.354 143.576 1.00 66.69  ? 310 ARG A N   1 
ATOM 1094 C CA  . ARG A 1 140 ? 171.808 178.101 143.927 1.00 66.80  ? 310 ARG A CA  1 
ATOM 1095 C C   . ARG A 1 140 ? 172.689 177.761 142.712 1.00 67.14  ? 310 ARG A C   1 
ATOM 1096 O O   . ARG A 1 140 ? 172.193 177.552 141.595 1.00 67.41  ? 310 ARG A O   1 
ATOM 1097 C CB  . ARG A 1 140 ? 171.897 176.954 144.954 1.00 66.61  ? 310 ARG A CB  1 
ATOM 1098 C CG  . ARG A 1 140 ? 171.222 177.199 146.286 1.00 65.60  ? 310 ARG A CG  1 
ATOM 1099 C CD  . ARG A 1 140 ? 171.220 175.913 147.102 1.00 67.08  ? 310 ARG A CD  1 
ATOM 1100 N NE  . ARG A 1 140 ? 170.312 175.943 148.253 1.00 66.88  ? 310 ARG A NE  1 
ATOM 1101 C CZ  . ARG A 1 140 ? 170.604 176.537 149.409 1.00 68.06  ? 310 ARG A CZ  1 
ATOM 1102 N NH1 . ARG A 1 140 ? 171.768 177.153 149.566 1.00 67.10  ? 310 ARG A NH1 1 
ATOM 1103 N NH2 . ARG A 1 140 ? 169.737 176.528 150.407 1.00 67.02  ? 310 ARG A NH2 1 
ATOM 1104 N N   . ASP A 1 141 ? 173.996 177.674 142.958 1.00 67.26  ? 311 ASP A N   1 
ATOM 1105 C CA  . ASP A 1 141 ? 174.977 177.331 141.935 1.00 67.60  ? 311 ASP A CA  1 
ATOM 1106 C C   . ASP A 1 141 ? 175.269 175.823 141.990 1.00 67.21  ? 311 ASP A C   1 
ATOM 1107 O O   . ASP A 1 141 ? 176.326 175.366 141.544 1.00 67.39  ? 311 ASP A O   1 
ATOM 1108 C CB  . ASP A 1 141 ? 176.267 178.159 142.112 1.00 67.86  ? 311 ASP A CB  1 
ATOM 1109 C CG  . ASP A 1 141 ? 176.858 178.056 143.537 1.00 71.15  ? 311 ASP A CG  1 
ATOM 1110 O OD1 . ASP A 1 141 ? 176.170 177.504 144.441 1.00 74.56  ? 311 ASP A OD1 1 
ATOM 1111 O OD2 . ASP A 1 141 ? 178.011 178.532 143.761 1.00 73.21  ? 311 ASP A OD2 1 
ATOM 1112 N N   . ARG A 1 142 ? 174.336 175.059 142.557 1.00 66.66  ? 312 ARG A N   1 
ATOM 1113 C CA  . ARG A 1 142 ? 174.489 173.612 142.676 1.00 66.36  ? 312 ARG A CA  1 
ATOM 1114 C C   . ARG A 1 142 ? 173.138 172.995 142.849 1.00 66.52  ? 312 ARG A C   1 
ATOM 1115 O O   . ARG A 1 142 ? 172.171 173.702 143.097 1.00 67.44  ? 312 ARG A O   1 
ATOM 1116 C CB  . ARG A 1 142 ? 175.337 173.253 143.898 1.00 65.99  ? 312 ARG A CB  1 
ATOM 1117 C CG  . ARG A 1 142 ? 174.725 173.680 145.210 1.00 64.91  ? 312 ARG A CG  1 
ATOM 1118 C CD  . ARG A 1 142 ? 175.442 173.110 146.418 1.00 63.33  ? 312 ARG A CD  1 
ATOM 1119 N NE  . ARG A 1 142 ? 174.819 173.584 147.650 1.00 64.29  ? 312 ARG A NE  1 
ATOM 1120 C CZ  . ARG A 1 142 ? 173.726 173.047 148.197 1.00 65.78  ? 312 ARG A CZ  1 
ATOM 1121 N NH1 . ARG A 1 142 ? 173.133 171.997 147.641 1.00 67.08  ? 312 ARG A NH1 1 
ATOM 1122 N NH2 . ARG A 1 142 ? 173.212 173.555 149.305 1.00 66.29  ? 312 ARG A NH2 1 
ATOM 1123 N N   . VAL A 1 143 ? 173.069 171.671 142.747 1.00 66.56  ? 313 VAL A N   1 
ATOM 1124 C CA  . VAL A 1 143 ? 171.815 170.945 142.945 1.00 66.12  ? 313 VAL A CA  1 
ATOM 1125 C C   . VAL A 1 143 ? 171.877 170.401 144.372 1.00 66.49  ? 313 VAL A C   1 
ATOM 1126 O O   . VAL A 1 143 ? 172.889 170.566 145.047 1.00 66.61  ? 313 VAL A O   1 
ATOM 1127 C CB  . VAL A 1 143 ? 171.650 169.772 141.953 1.00 66.02  ? 313 VAL A CB  1 
ATOM 1128 C CG1 . VAL A 1 143 ? 171.681 170.268 140.510 1.00 64.49  ? 313 VAL A CG1 1 
ATOM 1129 C CG2 . VAL A 1 143 ? 172.723 168.693 142.188 1.00 65.69  ? 313 VAL A CG2 1 
ATOM 1130 N N   . GLY A 1 144 ? 170.801 169.759 144.826 1.00 66.69  ? 314 GLY A N   1 
ATOM 1131 C CA  . GLY A 1 144 ? 170.749 169.171 146.145 1.00 66.18  ? 314 GLY A CA  1 
ATOM 1132 C C   . GLY A 1 144 ? 169.968 169.893 147.206 1.00 66.51  ? 314 GLY A C   1 
ATOM 1133 O O   . GLY A 1 144 ? 169.440 169.262 148.138 1.00 67.25  ? 314 GLY A O   1 
ATOM 1134 N N   . GLY A 1 145 ? 169.919 171.212 147.114 1.00 66.22  ? 315 GLY A N   1 
ATOM 1135 C CA  . GLY A 1 145 ? 169.200 171.997 148.113 1.00 66.46  ? 315 GLY A CA  1 
ATOM 1136 C C   . GLY A 1 145 ? 169.678 171.731 149.531 1.00 66.89  ? 315 GLY A C   1 
ATOM 1137 O O   . GLY A 1 145 ? 170.857 171.982 149.875 1.00 66.44  ? 315 GLY A O   1 
ATOM 1138 N N   . ARG A 1 146 ? 168.772 171.203 150.355 1.00 66.86  ? 316 ARG A N   1 
ATOM 1139 C CA  . ARG A 1 146 ? 169.121 170.898 151.751 1.00 67.17  ? 316 ARG A CA  1 
ATOM 1140 C C   . ARG A 1 146 ? 170.035 169.674 151.924 1.00 67.74  ? 316 ARG A C   1 
ATOM 1141 O O   . ARG A 1 146 ? 170.376 169.289 153.042 1.00 67.67  ? 316 ARG A O   1 
ATOM 1142 C CB  . ARG A 1 146 ? 167.900 170.911 152.658 1.00 66.88  ? 316 ARG A CB  1 
ATOM 1143 C CG  . ARG A 1 146 ? 167.502 172.353 152.987 1.00 65.81  ? 316 ARG A CG  1 
ATOM 1144 C CD  . ARG A 1 146 ? 166.169 172.442 153.672 1.00 64.71  ? 316 ARG A CD  1 
ATOM 1145 N NE  . ARG A 1 146 ? 165.034 172.307 152.766 1.00 64.60  ? 316 ARG A NE  1 
ATOM 1146 C CZ  . ARG A 1 146 ? 163.780 172.065 153.161 1.00 65.63  ? 316 ARG A CZ  1 
ATOM 1147 N NH1 . ARG A 1 146 ? 163.481 171.925 154.454 1.00 62.45  ? 316 ARG A NH1 1 
ATOM 1148 N NH2 . ARG A 1 146 ? 162.812 171.979 152.254 1.00 65.67  ? 316 ARG A NH2 1 
ATOM 1149 N N   . VAL A 1 147 ? 170.471 169.099 150.802 1.00 68.04  ? 317 VAL A N   1 
ATOM 1150 C CA  . VAL A 1 147 ? 171.427 168.003 150.840 1.00 68.10  ? 317 VAL A CA  1 
ATOM 1151 C C   . VAL A 1 147 ? 172.647 168.740 150.302 1.00 68.49  ? 317 VAL A C   1 
ATOM 1152 O O   . VAL A 1 147 ? 172.745 169.006 149.100 1.00 69.38  ? 317 VAL A O   1 
ATOM 1153 C CB  . VAL A 1 147 ? 171.033 166.799 149.989 1.00 68.05  ? 317 VAL A CB  1 
ATOM 1154 C CG1 . VAL A 1 147 ? 172.211 165.852 149.878 1.00 67.32  ? 317 VAL A CG1 1 
ATOM 1155 C CG2 . VAL A 1 147 ? 169.826 166.080 150.611 1.00 67.02  ? 317 VAL A CG2 1 
ATOM 1156 N N   . ALA A 1 148 ? 173.515 169.150 151.223 1.00 68.52  ? 318 ALA A N   1 
ATOM 1157 C CA  . ALA A 1 148 ? 174.701 169.929 150.929 1.00 68.45  ? 318 ALA A CA  1 
ATOM 1158 C C   . ALA A 1 148 ? 175.918 169.323 151.597 1.00 68.96  ? 318 ALA A C   1 
ATOM 1159 O O   . ALA A 1 148 ? 175.955 169.158 152.820 1.00 69.51  ? 318 ALA A O   1 
ATOM 1160 C CB  . ALA A 1 148 ? 174.496 171.337 151.424 1.00 68.06  ? 318 ALA A CB  1 
ATOM 1161 N N   . THR A 1 149 ? 176.931 169.021 150.795 1.00 69.07  ? 319 THR A N   1 
ATOM 1162 C CA  . THR A 1 149 ? 178.138 168.414 151.305 1.00 68.87  ? 319 THR A CA  1 
ATOM 1163 C C   . THR A 1 149 ? 179.365 169.298 151.151 1.00 69.17  ? 319 THR A C   1 
ATOM 1164 O O   . THR A 1 149 ? 179.596 169.891 150.106 1.00 68.68  ? 319 THR A O   1 
ATOM 1165 C CB  . THR A 1 149 ? 178.377 167.071 150.601 1.00 69.03  ? 319 THR A CB  1 
ATOM 1166 O OG1 . THR A 1 149 ? 177.182 166.276 150.689 1.00 69.37  ? 319 THR A OG1 1 
ATOM 1167 C CG2 . THR A 1 149 ? 179.558 166.317 151.217 1.00 67.97  ? 319 THR A CG2 1 
ATOM 1168 N N   . PHE A 1 150 ? 180.161 169.367 152.210 1.00 69.48  ? 320 PHE A N   1 
ATOM 1169 C CA  . PHE A 1 150 ? 181.372 170.140 152.182 1.00 69.78  ? 320 PHE A CA  1 
ATOM 1170 C C   . PHE A 1 150 ? 182.452 169.211 151.651 1.00 70.22  ? 320 PHE A C   1 
ATOM 1171 O O   . PHE A 1 150 ? 182.580 168.087 152.136 1.00 70.79  ? 320 PHE A O   1 
ATOM 1172 C CB  . PHE A 1 150 ? 181.722 170.623 153.581 1.00 69.53  ? 320 PHE A CB  1 
ATOM 1173 C CG  . PHE A 1 150 ? 183.063 171.255 153.676 1.00 69.03  ? 320 PHE A CG  1 
ATOM 1174 C CD1 . PHE A 1 150 ? 183.329 172.448 153.008 1.00 68.44  ? 320 PHE A CD1 1 
ATOM 1175 C CD2 . PHE A 1 150 ? 184.068 170.661 154.439 1.00 69.22  ? 320 PHE A CD2 1 
ATOM 1176 C CE1 . PHE A 1 150 ? 184.581 173.041 153.091 1.00 69.82  ? 320 PHE A CE1 1 
ATOM 1177 C CE2 . PHE A 1 150 ? 185.335 171.243 154.541 1.00 68.76  ? 320 PHE A CE2 1 
ATOM 1178 C CZ  . PHE A 1 150 ? 185.598 172.432 153.866 1.00 69.72  ? 320 PHE A CZ  1 
ATOM 1179 N N   . ARG A 1 151 ? 183.199 169.666 150.646 1.00 70.32  ? 321 ARG A N   1 
ATOM 1180 C CA  . ARG A 1 151 ? 184.267 168.870 150.048 1.00 70.47  ? 321 ARG A CA  1 
ATOM 1181 C C   . ARG A 1 151 ? 185.497 169.717 149.830 1.00 71.12  ? 321 ARG A C   1 
ATOM 1182 O O   . ARG A 1 151 ? 185.469 170.694 149.090 1.00 71.60  ? 321 ARG A O   1 
ATOM 1183 C CB  . ARG A 1 151 ? 183.843 168.261 148.703 1.00 70.41  ? 321 ARG A CB  1 
ATOM 1184 C CG  . ARG A 1 151 ? 182.925 167.056 148.810 1.00 70.37  ? 321 ARG A CG  1 
ATOM 1185 C CD  . ARG A 1 151 ? 182.530 166.471 147.452 1.00 69.67  ? 321 ARG A CD  1 
ATOM 1186 N NE  . ARG A 1 151 ? 181.205 165.852 147.539 1.00 68.71  ? 321 ARG A NE  1 
ATOM 1187 C CZ  . ARG A 1 151 ? 180.961 164.613 147.964 1.00 68.62  ? 321 ARG A CZ  1 
ATOM 1188 N NH1 . ARG A 1 151 ? 181.956 163.816 148.338 1.00 69.26  ? 321 ARG A NH1 1 
ATOM 1189 N NH2 . ARG A 1 151 ? 179.713 164.164 148.022 1.00 68.12  ? 321 ARG A NH2 1 
ATOM 1190 N N   . LYS A 1 152 ? 186.587 169.343 150.477 1.00 71.73  ? 322 LYS A N   1 
ATOM 1191 C CA  . LYS A 1 152 ? 187.835 170.053 150.314 1.00 72.29  ? 322 LYS A CA  1 
ATOM 1192 C C   . LYS A 1 152 ? 188.936 169.063 150.633 1.00 72.24  ? 322 LYS A C   1 
ATOM 1193 O O   . LYS A 1 152 ? 189.035 168.560 151.757 1.00 72.39  ? 322 LYS A O   1 
ATOM 1194 C CB  . LYS A 1 152 ? 187.891 171.297 151.195 1.00 72.63  ? 322 LYS A CB  1 
ATOM 1195 C CG  . LYS A 1 152 ? 189.082 172.180 150.886 1.00 74.87  ? 322 LYS A CG  1 
ATOM 1196 C CD  . LYS A 1 152 ? 188.911 173.576 151.443 1.00 78.68  ? 322 LYS A CD  1 
ATOM 1197 C CE  . LYS A 1 152 ? 190.214 174.346 151.325 1.00 81.07  ? 322 LYS A CE  1 
ATOM 1198 N NZ  . LYS A 1 152 ? 190.129 175.692 151.961 1.00 83.56  ? 322 LYS A NZ  1 
ATOM 1199 N N   . GLY A 1 153 ? 189.742 168.753 149.624 1.00 72.30  ? 323 GLY A N   1 
ATOM 1200 C CA  . GLY A 1 153 ? 190.824 167.793 149.783 1.00 72.55  ? 323 GLY A CA  1 
ATOM 1201 C C   . GLY A 1 153 ? 190.182 166.443 150.012 1.00 72.71  ? 323 GLY A C   1 
ATOM 1202 O O   . GLY A 1 153 ? 189.462 165.949 149.157 1.00 73.12  ? 323 GLY A O   1 
ATOM 1203 N N   . ASN A 1 154 ? 190.413 165.867 151.181 1.00 72.86  ? 324 ASN A N   1 
ATOM 1204 C CA  . ASN A 1 154 ? 189.833 164.581 151.532 1.00 73.08  ? 324 ASN A CA  1 
ATOM 1205 C C   . ASN A 1 154 ? 188.742 164.770 152.557 1.00 73.09  ? 324 ASN A C   1 
ATOM 1206 O O   . ASN A 1 154 ? 188.074 163.813 152.952 1.00 73.73  ? 324 ASN A O   1 
ATOM 1207 C CB  . ASN A 1 154 ? 190.904 163.649 152.083 1.00 73.32  ? 324 ASN A CB  1 
ATOM 1208 C CG  . ASN A 1 154 ? 191.923 163.278 151.043 1.00 74.30  ? 324 ASN A CG  1 
ATOM 1209 O OD1 . ASN A 1 154 ? 191.592 163.130 149.857 1.00 76.12  ? 324 ASN A OD1 1 
ATOM 1210 N ND2 . ASN A 1 154 ? 193.178 163.143 151.464 1.00 74.49  ? 324 ASN A ND2 1 
ATOM 1211 N N   . TYR A 1 155 ? 188.571 166.011 152.995 1.00 72.61  ? 325 TYR A N   1 
ATOM 1212 C CA  . TYR A 1 155 ? 187.563 166.328 153.972 1.00 71.99  ? 325 TYR A CA  1 
ATOM 1213 C C   . TYR A 1 155 ? 186.208 166.298 153.274 1.00 71.87  ? 325 TYR A C   1 
ATOM 1214 O O   . TYR A 1 155 ? 186.036 166.873 152.194 1.00 71.98  ? 325 TYR A O   1 
ATOM 1215 C CB  . TYR A 1 155 ? 187.820 167.703 154.576 1.00 71.90  ? 325 TYR A CB  1 
ATOM 1216 C CG  . TYR A 1 155 ? 189.125 167.842 155.312 1.00 72.74  ? 325 TYR A CG  1 
ATOM 1217 C CD1 . TYR A 1 155 ? 189.376 167.112 156.475 1.00 73.37  ? 325 TYR A CD1 1 
ATOM 1218 C CD2 . TYR A 1 155 ? 190.111 168.722 154.867 1.00 73.41  ? 325 TYR A CD2 1 
ATOM 1219 C CE1 . TYR A 1 155 ? 190.582 167.246 157.167 1.00 72.70  ? 325 TYR A CE1 1 
ATOM 1220 C CE2 . TYR A 1 155 ? 191.327 168.858 155.564 1.00 72.37  ? 325 TYR A CE2 1 
ATOM 1221 C CZ  . TYR A 1 155 ? 191.545 168.119 156.710 1.00 72.06  ? 325 TYR A CZ  1 
ATOM 1222 O OH  . TYR A 1 155 ? 192.727 168.239 157.403 1.00 72.69  ? 325 TYR A OH  1 
ATOM 1223 N N   . VAL A 1 156 ? 185.259 165.612 153.905 1.00 71.37  ? 326 VAL A N   1 
ATOM 1224 C CA  . VAL A 1 156 ? 183.902 165.469 153.410 1.00 70.67  ? 326 VAL A CA  1 
ATOM 1225 C C   . VAL A 1 156 ? 183.016 165.565 154.634 1.00 70.36  ? 326 VAL A C   1 
ATOM 1226 O O   . VAL A 1 156 ? 183.212 164.827 155.587 1.00 70.54  ? 326 VAL A O   1 
ATOM 1227 C CB  . VAL A 1 156 ? 183.695 164.075 152.765 1.00 70.78  ? 326 VAL A CB  1 
ATOM 1228 C CG1 . VAL A 1 156 ? 182.253 163.870 152.349 1.00 70.50  ? 326 VAL A CG1 1 
ATOM 1229 C CG2 . VAL A 1 156 ? 184.648 163.849 151.575 1.00 71.17  ? 326 VAL A CG2 1 
ATOM 1230 N N   . ALA A 1 157 ? 182.054 166.482 154.625 1.00 70.25  ? 327 ALA A N   1 
ATOM 1231 C CA  . ALA A 1 157 ? 181.141 166.661 155.762 1.00 69.89  ? 327 ALA A CA  1 
ATOM 1232 C C   . ALA A 1 157 ? 179.814 167.266 155.309 1.00 70.08  ? 327 ALA A C   1 
ATOM 1233 O O   . ALA A 1 157 ? 179.792 168.287 154.624 1.00 70.50  ? 327 ALA A O   1 
ATOM 1234 C CB  . ALA A 1 157 ? 181.781 167.523 156.827 1.00 69.21  ? 327 ALA A CB  1 
ATOM 1235 N N   . ASP A 1 158 ? 178.712 166.636 155.694 1.00 69.94  ? 328 ASP A N   1 
ATOM 1236 C CA  . ASP A 1 158 ? 177.401 167.123 155.315 1.00 70.14  ? 328 ASP A CA  1 
ATOM 1237 C C   . ASP A 1 158 ? 176.939 168.276 156.184 1.00 70.43  ? 328 ASP A C   1 
ATOM 1238 O O   . ASP A 1 158 ? 176.961 168.198 157.405 1.00 70.42  ? 328 ASP A O   1 
ATOM 1239 C CB  . ASP A 1 158 ? 176.377 165.996 155.377 1.00 69.97  ? 328 ASP A CB  1 
ATOM 1240 C CG  . ASP A 1 158 ? 176.527 165.019 154.234 1.00 70.80  ? 328 ASP A CG  1 
ATOM 1241 O OD1 . ASP A 1 158 ? 176.298 165.397 153.057 1.00 70.44  ? 328 ASP A OD1 1 
ATOM 1242 O OD2 . ASP A 1 158 ? 176.889 163.860 154.520 1.00 73.44  ? 328 ASP A OD2 1 
ATOM 1243 N N   . LEU A 1 159 ? 176.493 169.347 155.543 1.00 70.88  ? 329 LEU A N   1 
ATOM 1244 C CA  . LEU A 1 159 ? 176.004 170.498 156.269 1.00 70.91  ? 329 LEU A CA  1 
ATOM 1245 C C   . LEU A 1 159 ? 174.497 170.404 156.424 1.00 70.96  ? 329 LEU A C   1 
ATOM 1246 O O   . LEU A 1 159 ? 173.926 171.048 157.300 1.00 71.09  ? 329 LEU A O   1 
ATOM 1247 C CB  . LEU A 1 159 ? 176.410 171.785 155.566 1.00 70.85  ? 329 LEU A CB  1 
ATOM 1248 C CG  . LEU A 1 159 ? 177.901 172.118 155.676 1.00 71.94  ? 329 LEU A CG  1 
ATOM 1249 C CD1 . LEU A 1 159 ? 178.198 173.430 154.974 1.00 73.03  ? 329 LEU A CD1 1 
ATOM 1250 C CD2 . LEU A 1 159 ? 178.356 172.185 157.114 1.00 71.76  ? 329 LEU A CD2 1 
ATOM 1251 N N   . GLY A 1 160 ? 173.867 169.583 155.580 1.00 70.88  ? 330 GLY A N   1 
ATOM 1252 C CA  . GLY A 1 160 ? 172.422 169.361 155.614 1.00 70.85  ? 330 GLY A CA  1 
ATOM 1253 C C   . GLY A 1 160 ? 172.133 167.934 156.040 1.00 71.31  ? 330 GLY A C   1 
ATOM 1254 O O   . GLY A 1 160 ? 172.694 167.453 157.023 1.00 70.74  ? 330 GLY A O   1 
ATOM 1255 N N   . ALA A 1 161 ? 171.257 167.257 155.302 1.00 71.97  ? 331 ALA A N   1 
ATOM 1256 C CA  . ALA A 1 161 ? 170.894 165.866 155.584 1.00 72.65  ? 331 ALA A CA  1 
ATOM 1257 C C   . ALA A 1 161 ? 172.146 165.041 155.749 1.00 73.35  ? 331 ALA A C   1 
ATOM 1258 O O   . ALA A 1 161 ? 173.117 165.223 155.021 1.00 73.40  ? 331 ALA A O   1 
ATOM 1259 C CB  . ALA A 1 161 ? 170.067 165.302 154.473 1.00 72.75  ? 331 ALA A CB  1 
ATOM 1260 N N   . MET A 1 162 ? 172.129 164.126 156.706 1.00 74.36  ? 332 MET A N   1 
ATOM 1261 C CA  . MET A 1 162 ? 173.303 163.324 156.956 1.00 75.76  ? 332 MET A CA  1 
ATOM 1262 C C   . MET A 1 162 ? 173.001 161.880 157.304 1.00 74.67  ? 332 MET A C   1 
ATOM 1263 O O   . MET A 1 162 ? 173.803 160.990 156.999 1.00 74.59  ? 332 MET A O   1 
ATOM 1264 C CB  . MET A 1 162 ? 174.083 163.989 158.091 1.00 75.31  ? 332 MET A CB  1 
ATOM 1265 C CG  . MET A 1 162 ? 175.263 163.226 158.619 1.00 77.60  ? 332 MET A CG  1 
ATOM 1266 S SD  . MET A 1 162 ? 176.177 164.249 159.791 1.00 81.33  ? 332 MET A SD  1 
ATOM 1267 C CE  . MET A 1 162 ? 175.064 164.314 161.224 1.00 82.61  ? 332 MET A CE  1 
ATOM 1268 N N   . VAL A 1 163 ? 171.856 161.655 157.943 1.00 74.16  ? 333 VAL A N   1 
ATOM 1269 C CA  . VAL A 1 163 ? 171.475 160.319 158.394 1.00 73.95  ? 333 VAL A CA  1 
ATOM 1270 C C   . VAL A 1 163 ? 170.378 159.633 157.590 1.00 73.71  ? 333 VAL A C   1 
ATOM 1271 O O   . VAL A 1 163 ? 169.402 160.264 157.209 1.00 73.67  ? 333 VAL A O   1 
ATOM 1272 C CB  . VAL A 1 163 ? 171.023 160.370 159.881 1.00 73.94  ? 333 VAL A CB  1 
ATOM 1273 C CG1 . VAL A 1 163 ? 170.725 158.989 160.412 1.00 74.40  ? 333 VAL A CG1 1 
ATOM 1274 C CG2 . VAL A 1 163 ? 172.084 161.028 160.746 1.00 73.73  ? 333 VAL A CG2 1 
ATOM 1275 N N   . VAL A 1 164 ? 170.558 158.338 157.350 1.00 73.46  ? 334 VAL A N   1 
ATOM 1276 C CA  . VAL A 1 164 ? 169.576 157.509 156.666 1.00 73.51  ? 334 VAL A CA  1 
ATOM 1277 C C   . VAL A 1 164 ? 169.043 156.737 157.866 1.00 74.32  ? 334 VAL A C   1 
ATOM 1278 O O   . VAL A 1 164 ? 169.770 155.983 158.528 1.00 74.25  ? 334 VAL A O   1 
ATOM 1279 C CB  . VAL A 1 164 ? 170.182 156.591 155.600 1.00 73.25  ? 334 VAL A CB  1 
ATOM 1280 C CG1 . VAL A 1 164 ? 169.132 155.680 155.045 1.00 72.53  ? 334 VAL A CG1 1 
ATOM 1281 C CG2 . VAL A 1 164 ? 170.778 157.415 154.473 1.00 72.77  ? 334 VAL A CG2 1 
ATOM 1282 N N   . THR A 1 165 ? 167.787 157.000 158.197 1.00 75.00  ? 335 THR A N   1 
ATOM 1283 C CA  . THR A 1 165 ? 167.148 156.425 159.383 1.00 75.48  ? 335 THR A CA  1 
ATOM 1284 C C   . THR A 1 165 ? 166.575 155.028 159.254 1.00 74.93  ? 335 THR A C   1 
ATOM 1285 O O   . THR A 1 165 ? 165.394 154.816 159.521 1.00 75.52  ? 335 THR A O   1 
ATOM 1286 C CB  . THR A 1 165 ? 166.053 157.386 159.906 1.00 76.04  ? 335 THR A CB  1 
ATOM 1287 O OG1 . THR A 1 165 ? 165.363 158.007 158.786 1.00 78.75  ? 335 THR A OG1 1 
ATOM 1288 C CG2 . THR A 1 165 ? 166.704 158.475 160.755 1.00 75.68  ? 335 THR A CG2 1 
ATOM 1289 N N   . GLY A 1 166 ? 167.416 154.074 158.879 1.00 73.95  ? 336 GLY A N   1 
ATOM 1290 C CA  . GLY A 1 166 ? 166.974 152.703 158.718 1.00 73.25  ? 336 GLY A CA  1 
ATOM 1291 C C   . GLY A 1 166 ? 166.585 152.439 157.282 1.00 72.76  ? 336 GLY A C   1 
ATOM 1292 O O   . GLY A 1 166 ? 165.957 153.270 156.646 1.00 72.85  ? 336 GLY A O   1 
ATOM 1293 N N   . LEU A 1 167 ? 166.964 151.271 156.756 1.00 72.50  ? 337 LEU A N   1 
ATOM 1294 C CA  . LEU A 1 167 ? 166.696 150.979 155.320 1.00 72.10  ? 337 LEU A CA  1 
ATOM 1295 C C   . LEU A 1 167 ? 165.376 150.213 155.169 1.00 72.31  ? 337 LEU A C   1 
ATOM 1296 O O   . LEU A 1 167 ? 164.958 149.990 154.015 1.00 72.89  ? 337 LEU A O   1 
ATOM 1297 C CB  . LEU A 1 167 ? 167.869 150.176 154.748 1.00 71.63  ? 337 LEU A CB  1 
ATOM 1298 C CG  . LEU A 1 167 ? 169.189 150.938 154.647 1.00 71.00  ? 337 LEU A CG  1 
ATOM 1299 C CD1 . LEU A 1 167 ? 170.282 150.052 154.069 1.00 69.34  ? 337 LEU A CD1 1 
ATOM 1300 C CD2 . LEU A 1 167 ? 169.024 152.196 153.809 1.00 70.41  ? 337 LEU A CD2 1 
ATOM 1301 N N   . GLY A 1 168 ? 164.745 149.835 156.285 1.00 71.85  ? 338 GLY A N   1 
ATOM 1302 C CA  . GLY A 1 168 ? 163.495 149.053 156.220 1.00 71.38  ? 338 GLY A CA  1 
ATOM 1303 C C   . GLY A 1 168 ? 162.345 149.886 155.683 1.00 71.43  ? 338 GLY A C   1 
ATOM 1304 O O   . GLY A 1 168 ? 161.920 150.821 156.384 1.00 71.43  ? 338 GLY A O   1 
ATOM 1305 N N   . GLY A 1 169 ? 161.853 149.556 154.485 1.00 71.18  ? 339 GLY A N   1 
ATOM 1306 C CA  . GLY A 1 169 ? 160.744 150.313 153.871 1.00 70.74  ? 339 GLY A CA  1 
ATOM 1307 C C   . GLY A 1 169 ? 161.202 151.666 153.355 1.00 70.54  ? 339 GLY A C   1 
ATOM 1308 O O   . GLY A 1 169 ? 160.363 152.390 152.789 1.00 70.91  ? 339 GLY A O   1 
ATOM 1309 N N   . ASN A 1 170 ? 162.481 152.003 153.547 1.00 70.28  ? 340 ASN A N   1 
ATOM 1310 C CA  . ASN A 1 170 ? 163.011 153.261 153.058 1.00 69.84  ? 340 ASN A CA  1 
ATOM 1311 C C   . ASN A 1 170 ? 163.310 153.220 151.548 1.00 70.27  ? 340 ASN A C   1 
ATOM 1312 O O   . ASN A 1 170 ? 164.078 152.355 151.095 1.00 70.17  ? 340 ASN A O   1 
ATOM 1313 C CB  . ASN A 1 170 ? 164.277 153.564 153.850 1.00 69.46  ? 340 ASN A CB  1 
ATOM 1314 C CG  . ASN A 1 170 ? 164.815 154.948 153.611 1.00 69.08  ? 340 ASN A CG  1 
ATOM 1315 O OD1 . ASN A 1 170 ? 164.445 155.629 152.652 1.00 69.57  ? 340 ASN A OD1 1 
ATOM 1316 N ND2 . ASN A 1 170 ? 165.713 155.378 154.489 1.00 66.95  ? 340 ASN A ND2 1 
ATOM 1317 N N   . PRO A 1 171 ? 162.720 154.156 150.765 1.00 70.23  ? 341 PRO A N   1 
ATOM 1318 C CA  . PRO A 1 171 ? 163.027 154.242 149.339 1.00 70.45  ? 341 PRO A CA  1 
ATOM 1319 C C   . PRO A 1 171 ? 164.505 154.555 149.081 1.00 70.85  ? 341 PRO A C   1 
ATOM 1320 O O   . PRO A 1 171 ? 165.016 154.248 148.000 1.00 70.84  ? 341 PRO A O   1 
ATOM 1321 C CB  . PRO A 1 171 ? 162.119 155.367 148.838 1.00 70.28  ? 341 PRO A CB  1 
ATOM 1322 C CG  . PRO A 1 171 ? 161.806 156.172 150.047 1.00 70.79  ? 341 PRO A CG  1 
ATOM 1323 C CD  . PRO A 1 171 ? 161.748 155.182 151.171 1.00 70.41  ? 341 PRO A CD  1 
ATOM 1324 N N   . MET A 1 172 ? 165.196 155.111 150.073 1.00 71.24  ? 342 MET A N   1 
ATOM 1325 C CA  . MET A 1 172 ? 166.627 155.388 149.926 1.00 71.92  ? 342 MET A CA  1 
ATOM 1326 C C   . MET A 1 172 ? 167.419 154.082 149.824 1.00 71.95  ? 342 MET A C   1 
ATOM 1327 O O   . MET A 1 172 ? 168.577 154.087 149.411 1.00 72.28  ? 342 MET A O   1 
ATOM 1328 C CB  . MET A 1 172 ? 167.166 156.247 151.076 1.00 72.14  ? 342 MET A CB  1 
ATOM 1329 C CG  . MET A 1 172 ? 166.555 157.633 151.140 1.00 73.07  ? 342 MET A CG  1 
ATOM 1330 S SD  . MET A 1 172 ? 166.590 158.460 149.532 1.00 77.06  ? 342 MET A SD  1 
ATOM 1331 C CE  . MET A 1 172 ? 168.359 158.729 149.362 1.00 75.30  ? 342 MET A CE  1 
ATOM 1332 N N   . ALA A 1 173 ? 166.796 152.962 150.189 1.00 71.79  ? 343 ALA A N   1 
ATOM 1333 C CA  . ALA A 1 173 ? 167.464 151.672 150.092 1.00 71.89  ? 343 ALA A CA  1 
ATOM 1334 C C   . ALA A 1 173 ? 167.636 151.351 148.617 1.00 72.43  ? 343 ALA A C   1 
ATOM 1335 O O   . ALA A 1 173 ? 168.681 150.844 148.203 1.00 73.20  ? 343 ALA A O   1 
ATOM 1336 C CB  . ALA A 1 173 ? 166.668 150.604 150.776 1.00 71.76  ? 343 ALA A CB  1 
ATOM 1337 N N   . VAL A 1 174 ? 166.618 151.661 147.816 1.00 72.46  ? 344 VAL A N   1 
ATOM 1338 C CA  . VAL A 1 174 ? 166.689 151.431 146.387 1.00 72.68  ? 344 VAL A CA  1 
ATOM 1339 C C   . VAL A 1 174 ? 167.729 152.398 145.812 1.00 73.21  ? 344 VAL A C   1 
ATOM 1340 O O   . VAL A 1 174 ? 168.614 151.991 145.062 1.00 73.40  ? 344 VAL A O   1 
ATOM 1341 C CB  . VAL A 1 174 ? 165.310 151.619 145.688 1.00 72.60  ? 344 VAL A CB  1 
ATOM 1342 C CG1 . VAL A 1 174 ? 165.470 151.880 144.189 1.00 72.29  ? 344 VAL A CG1 1 
ATOM 1343 C CG2 . VAL A 1 174 ? 164.442 150.414 145.901 1.00 71.68  ? 344 VAL A CG2 1 
ATOM 1344 N N   . VAL A 1 175 ? 167.637 153.670 146.191 1.00 73.61  ? 345 VAL A N   1 
ATOM 1345 C CA  . VAL A 1 175 ? 168.573 154.680 145.703 1.00 74.12  ? 345 VAL A CA  1 
ATOM 1346 C C   . VAL A 1 175 ? 170.025 154.311 146.000 1.00 74.39  ? 345 VAL A C   1 
ATOM 1347 O O   . VAL A 1 175 ? 170.894 154.511 145.155 1.00 74.18  ? 345 VAL A O   1 
ATOM 1348 C CB  . VAL A 1 175 ? 168.244 156.099 146.244 1.00 74.30  ? 345 VAL A CB  1 
ATOM 1349 C CG1 . VAL A 1 175 ? 169.298 157.123 145.800 1.00 74.38  ? 345 VAL A CG1 1 
ATOM 1350 C CG2 . VAL A 1 175 ? 166.868 156.543 145.768 1.00 73.82  ? 345 VAL A CG2 1 
ATOM 1351 N N   . SER A 1 176 ? 170.274 153.750 147.179 1.00 74.90  ? 346 SER A N   1 
ATOM 1352 C CA  . SER A 1 176 ? 171.631 153.361 147.572 1.00 75.89  ? 346 SER A CA  1 
ATOM 1353 C C   . SER A 1 176 ? 172.217 152.214 146.740 1.00 76.28  ? 346 SER A C   1 
ATOM 1354 O O   . SER A 1 176 ? 173.424 152.020 146.725 1.00 76.82  ? 346 SER A O   1 
ATOM 1355 C CB  . SER A 1 176 ? 171.709 153.050 149.068 1.00 75.83  ? 346 SER A CB  1 
ATOM 1356 O OG  . SER A 1 176 ? 171.477 151.677 149.311 1.00 77.78  ? 346 SER A OG  1 
ATOM 1357 N N   . LYS A 1 177 ? 171.372 151.462 146.046 1.00 76.90  ? 347 LYS A N   1 
ATOM 1358 C CA  . LYS A 1 177 ? 171.856 150.381 145.190 1.00 77.35  ? 347 LYS A CA  1 
ATOM 1359 C C   . LYS A 1 177 ? 172.114 150.950 143.810 1.00 77.35  ? 347 LYS A C   1 
ATOM 1360 O O   . LYS A 1 177 ? 172.899 150.405 143.047 1.00 77.73  ? 347 LYS A O   1 
ATOM 1361 C CB  . LYS A 1 177 ? 170.837 149.254 145.076 1.00 77.39  ? 347 LYS A CB  1 
ATOM 1362 C CG  . LYS A 1 177 ? 170.887 148.278 146.218 1.00 79.54  ? 347 LYS A CG  1 
ATOM 1363 C CD  . LYS A 1 177 ? 169.649 147.411 146.248 1.00 83.11  ? 347 LYS A CD  1 
ATOM 1364 C CE  . LYS A 1 177 ? 169.530 146.695 147.582 1.00 85.28  ? 347 LYS A CE  1 
ATOM 1365 N NZ  . LYS A 1 177 ? 169.069 145.290 147.382 1.00 87.66  ? 347 LYS A NZ  1 
ATOM 1366 N N   . GLN A 1 178 ? 171.444 152.066 143.503 1.00 77.38  ? 348 GLN A N   1 
ATOM 1367 C CA  . GLN A 1 178 ? 171.642 152.740 142.194 1.00 77.56  ? 348 GLN A CA  1 
ATOM 1368 C C   . GLN A 1 178 ? 172.708 153.826 142.363 1.00 78.40  ? 348 GLN A C   1 
ATOM 1369 O O   . GLN A 1 178 ? 173.796 153.681 141.772 1.00 78.38  ? 348 GLN A O   1 
ATOM 1370 C CB  . GLN A 1 178 ? 170.322 153.343 141.713 1.00 77.03  ? 348 GLN A CB  1 
ATOM 1371 C CG  . GLN A 1 178 ? 169.173 152.345 141.677 1.00 75.38  ? 348 GLN A CG  1 
ATOM 1372 C CD  . GLN A 1 178 ? 167.852 153.013 141.386 1.00 73.39  ? 348 GLN A CD  1 
ATOM 1373 O OE1 . GLN A 1 178 ? 167.753 154.236 141.324 1.00 72.10  ? 348 GLN A OE1 1 
ATOM 1374 N NE2 . GLN A 1 178 ? 166.817 152.208 141.208 1.00 73.88  ? 348 GLN A NE2 1 
ATOM 1375 N N   . VAL A 1 179 ? 172.405 154.866 143.146 1.00 79.75  ? 349 VAL A N   1 
ATOM 1376 C CA  . VAL A 1 179 ? 173.392 155.957 143.409 1.00 81.22  ? 349 VAL A CA  1 
ATOM 1377 C C   . VAL A 1 179 ? 174.570 155.374 144.194 1.00 82.39  ? 349 VAL A C   1 
ATOM 1378 O O   . VAL A 1 179 ? 174.318 154.670 145.192 1.00 82.60  ? 349 VAL A O   1 
ATOM 1379 C CB  . VAL A 1 179 ? 172.747 157.125 144.178 1.00 81.02  ? 349 VAL A CB  1 
ATOM 1380 C CG1 . VAL A 1 179 ? 173.783 158.140 144.636 1.00 81.33  ? 349 VAL A CG1 1 
ATOM 1381 C CG2 . VAL A 1 179 ? 171.649 157.800 143.373 1.00 81.35  ? 349 VAL A CG2 1 
ATOM 1382 N N   . ASN A 1 180 ? 175.802 155.663 143.765 1.00 83.76  ? 350 ASN A N   1 
ATOM 1383 C CA  . ASN A 1 180 ? 176.995 155.201 144.524 1.00 85.13  ? 350 ASN A CA  1 
ATOM 1384 C C   . ASN A 1 180 ? 176.902 155.760 145.946 1.00 85.35  ? 350 ASN A C   1 
ATOM 1385 O O   . ASN A 1 180 ? 177.044 156.989 146.103 1.00 85.93  ? 350 ASN A O   1 
ATOM 1386 C CB  . ASN A 1 180 ? 178.302 155.607 143.840 1.00 85.53  ? 350 ASN A CB  1 
ATOM 1387 C CG  . ASN A 1 180 ? 179.532 155.113 144.572 1.00 87.50  ? 350 ASN A CG  1 
ATOM 1388 O OD1 . ASN A 1 180 ? 179.426 154.387 145.558 1.00 88.48  ? 350 ASN A OD1 1 
ATOM 1389 N ND2 . ASN A 1 180 ? 180.704 155.499 144.095 1.00 89.38  ? 350 ASN A ND2 1 
ATOM 1390 N N   . MET A 1 181 ? 176.669 154.895 146.936 1.00 85.46  ? 351 MET A N   1 
ATOM 1391 C CA  . MET A 1 181 ? 176.499 155.366 148.311 1.00 85.18  ? 351 MET A CA  1 
ATOM 1392 C C   . MET A 1 181 ? 177.254 154.438 149.218 1.00 85.75  ? 351 MET A C   1 
ATOM 1393 O O   . MET A 1 181 ? 177.100 153.219 149.136 1.00 86.36  ? 351 MET A O   1 
ATOM 1394 C CB  . MET A 1 181 ? 175.035 155.368 148.731 1.00 85.38  ? 351 MET A CB  1 
ATOM 1395 C CG  . MET A 1 181 ? 174.289 156.651 148.469 1.00 84.59  ? 351 MET A CG  1 
ATOM 1396 S SD  . MET A 1 181 ? 172.591 156.501 149.064 1.00 83.89  ? 351 MET A SD  1 
ATOM 1397 C CE  . MET A 1 181 ? 172.635 157.447 150.574 1.00 84.45  ? 351 MET A CE  1 
ATOM 1398 N N   . GLU A 1 182 ? 178.070 155.018 150.084 1.00 85.66  ? 352 GLU A N   1 
ATOM 1399 C CA  . GLU A 1 182 ? 178.874 154.252 151.013 1.00 85.71  ? 352 GLU A CA  1 
ATOM 1400 C C   . GLU A 1 182 ? 178.267 154.419 152.398 1.00 84.75  ? 352 GLU A C   1 
ATOM 1401 O O   . GLU A 1 182 ? 178.655 155.310 153.146 1.00 84.89  ? 352 GLU A O   1 
ATOM 1402 C CB  . GLU A 1 182 ? 180.303 154.784 150.957 1.00 85.51  ? 352 GLU A CB  1 
ATOM 1403 C CG  . GLU A 1 182 ? 181.346 153.914 151.626 1.00 87.65  ? 352 GLU A CG  1 
ATOM 1404 C CD  . GLU A 1 182 ? 182.776 154.301 151.230 1.00 87.82  ? 352 GLU A CD  1 
ATOM 1405 O OE1 . GLU A 1 182 ? 182.939 154.990 150.180 1.00 90.31  ? 352 GLU A OE1 1 
ATOM 1406 O OE2 . GLU A 1 182 ? 183.721 153.908 151.963 1.00 88.79  ? 352 GLU A OE2 1 
ATOM 1407 N N   . LEU A 1 183 ? 177.295 153.573 152.725 1.00 83.89  ? 353 LEU A N   1 
ATOM 1408 C CA  . LEU A 1 183 ? 176.614 153.648 154.020 1.00 83.12  ? 353 LEU A CA  1 
ATOM 1409 C C   . LEU A 1 183 ? 177.379 152.992 155.162 1.00 83.01  ? 353 LEU A C   1 
ATOM 1410 O O   . LEU A 1 183 ? 177.858 151.864 155.032 1.00 82.91  ? 353 LEU A O   1 
ATOM 1411 C CB  . LEU A 1 183 ? 175.212 153.046 153.917 1.00 82.84  ? 353 LEU A CB  1 
ATOM 1412 C CG  . LEU A 1 183 ? 174.317 153.659 152.846 1.00 82.00  ? 353 LEU A CG  1 
ATOM 1413 C CD1 . LEU A 1 183 ? 173.064 152.839 152.699 1.00 81.72  ? 353 LEU A CD1 1 
ATOM 1414 C CD2 . LEU A 1 183 ? 173.992 155.105 153.169 1.00 80.34  ? 353 LEU A CD2 1 
ATOM 1415 N N   . ALA A 1 184 ? 177.474 153.702 156.282 1.00 82.88  ? 354 ALA A N   1 
ATOM 1416 C CA  . ALA A 1 184 ? 178.181 153.211 157.465 1.00 82.80  ? 354 ALA A CA  1 
ATOM 1417 C C   . ALA A 1 184 ? 177.297 153.308 158.695 1.00 83.07  ? 354 ALA A C   1 
ATOM 1418 O O   . ALA A 1 184 ? 176.712 154.355 158.960 1.00 83.20  ? 354 ALA A O   1 
ATOM 1419 C CB  . ALA A 1 184 ? 179.454 153.999 157.677 1.00 82.48  ? 354 ALA A CB  1 
ATOM 1420 N N   . LYS A 1 185 ? 177.206 152.220 159.453 1.00 83.52  ? 355 LYS A N   1 
ATOM 1421 C CA  . LYS A 1 185 ? 176.383 152.196 160.658 1.00 84.13  ? 355 LYS A CA  1 
ATOM 1422 C C   . LYS A 1 185 ? 176.861 153.167 161.719 1.00 83.76  ? 355 LYS A C   1 
ATOM 1423 O O   . LYS A 1 185 ? 178.055 153.390 161.888 1.00 83.69  ? 355 LYS A O   1 
ATOM 1424 C CB  . LYS A 1 185 ? 176.302 150.784 161.246 1.00 84.15  ? 355 LYS A CB  1 
ATOM 1425 C CG  . LYS A 1 185 ? 175.338 149.871 160.495 1.00 85.65  ? 355 LYS A CG  1 
ATOM 1426 C CD  . LYS A 1 185 ? 175.441 148.403 160.914 1.00 85.85  ? 355 LYS A CD  1 
ATOM 1427 C CE  . LYS A 1 185 ? 174.734 147.514 159.884 1.00 88.48  ? 355 LYS A CE  1 
ATOM 1428 N NZ  . LYS A 1 185 ? 175.098 146.077 160.053 1.00 89.99  ? 355 LYS A NZ  1 
ATOM 1429 N N   . ILE A 1 186 ? 175.899 153.754 162.415 1.00 83.86  ? 356 ILE A N   1 
ATOM 1430 C CA  . ILE A 1 186 ? 176.166 154.688 163.485 1.00 84.06  ? 356 ILE A CA  1 
ATOM 1431 C C   . ILE A 1 186 ? 176.092 153.908 164.796 1.00 84.22  ? 356 ILE A C   1 
ATOM 1432 O O   . ILE A 1 186 ? 175.014 153.452 165.179 1.00 84.28  ? 356 ILE A O   1 
ATOM 1433 C CB  . ILE A 1 186 ? 175.091 155.785 163.540 1.00 84.02  ? 356 ILE A CB  1 
ATOM 1434 C CG1 . ILE A 1 186 ? 175.130 156.654 162.287 1.00 84.07  ? 356 ILE A CG1 1 
ATOM 1435 C CG2 . ILE A 1 186 ? 175.250 156.646 164.791 1.00 84.13  ? 356 ILE A CG2 1 
ATOM 1436 C CD1 . ILE A 1 186 ? 173.976 157.648 162.211 1.00 84.29  ? 356 ILE A CD1 1 
ATOM 1437 N N   . LYS A 1 187 ? 177.223 153.753 165.481 1.00 84.45  ? 357 LYS A N   1 
ATOM 1438 C CA  . LYS A 1 187 ? 177.242 153.046 166.763 1.00 84.93  ? 357 LYS A CA  1 
ATOM 1439 C C   . LYS A 1 187 ? 176.471 153.938 167.726 1.00 85.05  ? 357 LYS A C   1 
ATOM 1440 O O   . LYS A 1 187 ? 176.719 155.140 167.782 1.00 85.08  ? 357 LYS A O   1 
ATOM 1441 C CB  . LYS A 1 187 ? 178.675 152.829 167.249 1.00 85.00  ? 357 LYS A CB  1 
ATOM 1442 C CG  . LYS A 1 187 ? 179.576 152.085 166.266 1.00 85.81  ? 357 LYS A CG  1 
ATOM 1443 C CD  . LYS A 1 187 ? 180.871 151.633 166.925 1.00 87.09  ? 357 LYS A CD  1 
ATOM 1444 C CE  . LYS A 1 187 ? 181.846 151.074 165.900 1.00 88.04  ? 357 LYS A CE  1 
ATOM 1445 N NZ  . LYS A 1 187 ? 182.902 150.262 166.571 1.00 89.35  ? 357 LYS A NZ  1 
ATOM 1446 N N   . GLN A 1 188 ? 175.515 153.382 168.460 1.00 85.32  ? 358 GLN A N   1 
ATOM 1447 C CA  . GLN A 1 188 ? 174.717 154.222 169.362 1.00 85.72  ? 358 GLN A CA  1 
ATOM 1448 C C   . GLN A 1 188 ? 175.358 154.667 170.698 1.00 85.11  ? 358 GLN A C   1 
ATOM 1449 O O   . GLN A 1 188 ? 174.817 155.560 171.364 1.00 85.52  ? 358 GLN A O   1 
ATOM 1450 C CB  . GLN A 1 188 ? 173.296 153.656 169.552 1.00 86.47  ? 358 GLN A CB  1 
ATOM 1451 C CG  . GLN A 1 188 ? 172.423 153.637 168.269 1.00 88.91  ? 358 GLN A CG  1 
ATOM 1452 C CD  . GLN A 1 188 ? 172.149 155.028 167.676 1.00 93.18  ? 358 GLN A CD  1 
ATOM 1453 O OE1 . GLN A 1 188 ? 171.924 156.002 168.406 1.00 96.27  ? 358 GLN A OE1 1 
ATOM 1454 N NE2 . GLN A 1 188 ? 172.150 155.116 166.345 1.00 93.93  ? 358 GLN A NE2 1 
ATOM 1455 N N   . LYS A 1 189 ? 176.504 154.100 171.080 1.00 83.90  ? 359 LYS A N   1 
ATOM 1456 C CA  . LYS A 1 189 ? 177.145 154.532 172.330 1.00 82.85  ? 359 LYS A CA  1 
ATOM 1457 C C   . LYS A 1 189 ? 177.516 156.013 172.214 1.00 81.63  ? 359 LYS A C   1 
ATOM 1458 O O   . LYS A 1 189 ? 178.147 156.424 171.237 1.00 81.45  ? 359 LYS A O   1 
ATOM 1459 C CB  . LYS A 1 189 ? 178.372 153.685 172.686 1.00 82.97  ? 359 LYS A CB  1 
ATOM 1460 C CG  . LYS A 1 189 ? 178.561 153.529 174.188 1.00 83.29  ? 359 LYS A CG  1 
ATOM 1461 C CD  . LYS A 1 189 ? 179.750 152.636 174.547 1.00 83.69  ? 359 LYS A CD  1 
ATOM 1462 C CE  . LYS A 1 189 ? 180.937 153.450 175.078 1.00 84.65  ? 359 LYS A CE  1 
ATOM 1463 N NZ  . LYS A 1 189 ? 182.014 152.592 175.649 1.00 83.75  ? 359 LYS A NZ  1 
ATOM 1464 N N   . CYS A 1 190 ? 177.100 156.797 173.208 1.00 80.07  ? 360 CYS A N   1 
ATOM 1465 C CA  . CYS A 1 190 ? 177.328 158.233 173.242 1.00 78.94  ? 360 CYS A CA  1 
ATOM 1466 C C   . CYS A 1 190 ? 177.608 158.701 174.661 1.00 78.14  ? 360 CYS A C   1 
ATOM 1467 O O   . CYS A 1 190 ? 176.680 159.034 175.391 1.00 78.25  ? 360 CYS A O   1 
ATOM 1468 C CB  . CYS A 1 190 ? 176.074 158.941 172.691 1.00 79.04  ? 360 CYS A CB  1 
ATOM 1469 S SG  . CYS A 1 190 ? 176.096 160.757 172.655 1.00 78.71  ? 360 CYS A SG  1 
ATOM 1470 N N   . PRO A 1 191 ? 178.889 158.707 175.081 1.00 77.50  ? 361 PRO A N   1 
ATOM 1471 C CA  . PRO A 1 191 ? 179.185 159.271 176.402 1.00 76.73  ? 361 PRO A CA  1 
ATOM 1472 C C   . PRO A 1 191 ? 178.905 160.768 176.455 1.00 76.06  ? 361 PRO A C   1 
ATOM 1473 O O   . PRO A 1 191 ? 178.928 161.435 175.425 1.00 76.15  ? 361 PRO A O   1 
ATOM 1474 C CB  . PRO A 1 191 ? 180.682 158.997 176.592 1.00 76.40  ? 361 PRO A CB  1 
ATOM 1475 C CG  . PRO A 1 191 ? 181.222 158.742 175.263 1.00 76.73  ? 361 PRO A CG  1 
ATOM 1476 C CD  . PRO A 1 191 ? 180.100 158.187 174.423 1.00 77.57  ? 361 PRO A CD  1 
ATOM 1477 N N   . LEU A 1 192 ? 178.617 161.274 177.648 1.00 75.42  ? 362 LEU A N   1 
ATOM 1478 C CA  . LEU A 1 192 ? 178.335 162.689 177.843 1.00 74.86  ? 362 LEU A CA  1 
ATOM 1479 C C   . LEU A 1 192 ? 179.356 163.250 178.804 1.00 74.64  ? 362 LEU A C   1 
ATOM 1480 O O   . LEU A 1 192 ? 179.765 162.566 179.731 1.00 74.77  ? 362 LEU A O   1 
ATOM 1481 C CB  . LEU A 1 192 ? 176.932 162.904 178.413 1.00 74.62  ? 362 LEU A CB  1 
ATOM 1482 C CG  . LEU A 1 192 ? 175.720 162.157 177.858 1.00 74.04  ? 362 LEU A CG  1 
ATOM 1483 C CD1 . LEU A 1 192 ? 174.513 162.477 178.712 1.00 73.30  ? 362 LEU A CD1 1 
ATOM 1484 C CD2 . LEU A 1 192 ? 175.448 162.496 176.398 1.00 73.29  ? 362 LEU A CD2 1 
ATOM 1485 N N   . TYR A 1 193 ? 179.765 164.490 178.581 1.00 74.55  ? 363 TYR A N   1 
ATOM 1486 C CA  . TYR A 1 193 ? 180.738 165.135 179.445 1.00 74.90  ? 363 TYR A CA  1 
ATOM 1487 C C   . TYR A 1 193 ? 180.151 166.428 179.974 1.00 75.40  ? 363 TYR A C   1 
ATOM 1488 O O   . TYR A 1 193 ? 179.714 167.273 179.191 1.00 75.54  ? 363 TYR A O   1 
ATOM 1489 C CB  . TYR A 1 193 ? 182.037 165.418 178.684 1.00 74.68  ? 363 TYR A CB  1 
ATOM 1490 C CG  . TYR A 1 193 ? 182.696 164.184 178.105 1.00 74.18  ? 363 TYR A CG  1 
ATOM 1491 C CD1 . TYR A 1 193 ? 182.359 163.725 176.834 1.00 72.76  ? 363 TYR A CD1 1 
ATOM 1492 C CD2 . TYR A 1 193 ? 183.656 163.473 178.833 1.00 73.26  ? 363 TYR A CD2 1 
ATOM 1493 C CE1 . TYR A 1 193 ? 182.949 162.597 176.298 1.00 72.56  ? 363 TYR A CE1 1 
ATOM 1494 C CE2 . TYR A 1 193 ? 184.259 162.337 178.305 1.00 73.21  ? 363 TYR A CE2 1 
ATOM 1495 C CZ  . TYR A 1 193 ? 183.899 161.909 177.032 1.00 74.39  ? 363 TYR A CZ  1 
ATOM 1496 O OH  . TYR A 1 193 ? 184.486 160.789 176.489 1.00 74.95  ? 363 TYR A OH  1 
ATOM 1497 N N   . GLU A 1 194 ? 180.134 166.576 181.298 1.00 75.91  ? 364 GLU A N   1 
ATOM 1498 C CA  . GLU A 1 194 ? 179.602 167.786 181.919 1.00 76.88  ? 364 GLU A CA  1 
ATOM 1499 C C   . GLU A 1 194 ? 180.487 168.959 181.544 1.00 76.99  ? 364 GLU A C   1 
ATOM 1500 O O   . GLU A 1 194 ? 181.604 168.772 181.068 1.00 76.69  ? 364 GLU A O   1 
ATOM 1501 C CB  . GLU A 1 194 ? 179.559 167.662 183.440 1.00 76.84  ? 364 GLU A CB  1 
ATOM 1502 C CG  . GLU A 1 194 ? 178.398 166.866 184.027 1.00 77.74  ? 364 GLU A CG  1 
ATOM 1503 C CD  . GLU A 1 194 ? 178.658 166.477 185.480 1.00 78.35  ? 364 GLU A CD  1 
ATOM 1504 O OE1 . GLU A 1 194 ? 178.779 167.382 186.346 1.00 80.57  ? 364 GLU A OE1 1 
ATOM 1505 O OE2 . GLU A 1 194 ? 178.765 165.261 185.759 1.00 80.91  ? 364 GLU A OE2 1 
ATOM 1506 N N   . ALA A 1 195 ? 179.986 170.170 181.773 1.00 77.77  ? 365 ALA A N   1 
ATOM 1507 C CA  . ALA A 1 195 ? 180.722 171.395 181.459 1.00 78.32  ? 365 ALA A CA  1 
ATOM 1508 C C   . ALA A 1 195 ? 182.163 171.407 181.988 1.00 78.59  ? 365 ALA A C   1 
ATOM 1509 O O   . ALA A 1 195 ? 183.054 171.940 181.334 1.00 78.99  ? 365 ALA A O   1 
ATOM 1510 C CB  . ALA A 1 195 ? 179.950 172.622 181.946 1.00 78.49  ? 365 ALA A CB  1 
ATOM 1511 N N   . ASN A 1 196 ? 182.394 170.803 183.155 1.00 78.75  ? 366 ASN A N   1 
ATOM 1512 C CA  . ASN A 1 196 ? 183.737 170.739 183.741 1.00 78.74  ? 366 ASN A CA  1 
ATOM 1513 C C   . ASN A 1 196 ? 184.687 169.812 182.961 1.00 78.88  ? 366 ASN A C   1 
ATOM 1514 O O   . ASN A 1 196 ? 185.887 169.735 183.255 1.00 78.86  ? 366 ASN A O   1 
ATOM 1515 C CB  . ASN A 1 196 ? 183.659 170.322 185.215 1.00 78.59  ? 366 ASN A CB  1 
ATOM 1516 C CG  . ASN A 1 196 ? 183.298 168.848 185.399 1.00 78.74  ? 366 ASN A CG  1 
ATOM 1517 O OD1 . ASN A 1 196 ? 182.941 168.148 184.449 1.00 79.02  ? 366 ASN A OD1 1 
ATOM 1518 N ND2 . ASN A 1 196 ? 183.387 168.374 186.634 1.00 77.68  ? 366 ASN A ND2 1 
ATOM 1519 N N   . GLY A 1 197 ? 184.130 169.097 181.984 1.00 78.93  ? 367 GLY A N   1 
ATOM 1520 C CA  . GLY A 1 197 ? 184.887 168.173 181.149 1.00 79.15  ? 367 GLY A CA  1 
ATOM 1521 C C   . GLY A 1 197 ? 184.930 166.726 181.607 1.00 79.62  ? 367 GLY A C   1 
ATOM 1522 O O   . GLY A 1 197 ? 185.417 165.869 180.879 1.00 79.59  ? 367 GLY A O   1 
ATOM 1523 N N   . GLN A 1 198 ? 184.446 166.437 182.810 1.00 80.16  ? 368 GLN A N   1 
ATOM 1524 C CA  . GLN A 1 198 ? 184.467 165.058 183.306 1.00 80.86  ? 368 GLN A CA  1 
ATOM 1525 C C   . GLN A 1 198 ? 183.241 164.260 182.868 1.00 81.00  ? 368 GLN A C   1 
ATOM 1526 O O   . GLN A 1 198 ? 182.131 164.783 182.805 1.00 81.42  ? 368 GLN A O   1 
ATOM 1527 C CB  . GLN A 1 198 ? 184.701 165.008 184.825 1.00 81.12  ? 368 GLN A CB  1 
ATOM 1528 C CG  . GLN A 1 198 ? 186.196 164.893 185.198 1.00 82.04  ? 368 GLN A CG  1 
ATOM 1529 C CD  . GLN A 1 198 ? 186.508 165.381 186.613 1.00 84.53  ? 368 GLN A CD  1 
ATOM 1530 O OE1 . GLN A 1 198 ? 185.704 166.080 187.235 1.00 85.98  ? 368 GLN A OE1 1 
ATOM 1531 N NE2 . GLN A 1 198 ? 187.686 165.023 187.124 1.00 84.55  ? 368 GLN A NE2 1 
ATOM 1532 N N   . ALA A 1 199 ? 183.460 162.994 182.534 1.00 81.22  ? 369 ALA A N   1 
ATOM 1533 C CA  . ALA A 1 199 ? 182.396 162.105 182.068 1.00 81.47  ? 369 ALA A CA  1 
ATOM 1534 C C   . ALA A 1 199 ? 181.285 161.838 183.083 1.00 81.77  ? 369 ALA A C   1 
ATOM 1535 O O   . ALA A 1 199 ? 181.501 161.903 184.302 1.00 81.80  ? 369 ALA A O   1 
ATOM 1536 C CB  . ALA A 1 199 ? 182.996 160.790 181.591 1.00 81.54  ? 369 ALA A CB  1 
ATOM 1537 N N   . VAL A 1 200 ? 180.101 161.525 182.561 1.00 82.00  ? 370 VAL A N   1 
ATOM 1538 C CA  . VAL A 1 200 ? 178.940 161.212 183.384 1.00 82.44  ? 370 VAL A CA  1 
ATOM 1539 C C   . VAL A 1 200 ? 178.940 159.704 183.659 1.00 83.04  ? 370 VAL A C   1 
ATOM 1540 O O   . VAL A 1 200 ? 178.939 158.906 182.728 1.00 82.79  ? 370 VAL A O   1 
ATOM 1541 C CB  . VAL A 1 200 ? 177.616 161.650 182.705 1.00 82.36  ? 370 VAL A CB  1 
ATOM 1542 C CG1 . VAL A 1 200 ? 176.404 161.063 183.418 1.00 81.87  ? 370 VAL A CG1 1 
ATOM 1543 C CG2 . VAL A 1 200 ? 177.514 163.170 182.651 1.00 82.43  ? 370 VAL A CG2 1 
ATOM 1544 N N   . PRO A 1 201 ? 178.962 159.308 184.946 1.00 83.84  ? 371 PRO A N   1 
ATOM 1545 C CA  . PRO A 1 201 ? 178.912 157.886 185.297 1.00 84.62  ? 371 PRO A CA  1 
ATOM 1546 C C   . PRO A 1 201 ? 177.734 157.164 184.640 1.00 85.60  ? 371 PRO A C   1 
ATOM 1547 O O   . PRO A 1 201 ? 176.686 157.771 184.399 1.00 85.74  ? 371 PRO A O   1 
ATOM 1548 C CB  . PRO A 1 201 ? 178.734 157.904 186.815 1.00 84.48  ? 371 PRO A CB  1 
ATOM 1549 C CG  . PRO A 1 201 ? 179.304 159.198 187.251 1.00 84.16  ? 371 PRO A CG  1 
ATOM 1550 C CD  . PRO A 1 201 ? 179.049 160.172 186.136 1.00 83.84  ? 371 PRO A CD  1 
ATOM 1551 N N   . LYS A 1 202 ? 177.922 155.876 184.354 1.00 86.68  ? 372 LYS A N   1 
ATOM 1552 C CA  . LYS A 1 202 ? 176.900 155.024 183.727 1.00 87.63  ? 372 LYS A CA  1 
ATOM 1553 C C   . LYS A 1 202 ? 175.561 155.120 184.456 1.00 87.14  ? 372 LYS A C   1 
ATOM 1554 O O   . LYS A 1 202 ? 174.514 155.244 183.822 1.00 87.31  ? 372 LYS A O   1 
ATOM 1555 C CB  . LYS A 1 202 ? 177.364 153.555 183.729 1.00 87.87  ? 372 LYS A CB  1 
ATOM 1556 C CG  . LYS A 1 202 ? 177.878 153.024 182.385 1.00 89.32  ? 372 LYS A CG  1 
ATOM 1557 C CD  . LYS A 1 202 ? 178.585 151.675 182.582 1.00 89.00  ? 372 LYS A CD  1 
ATOM 1558 C CE  . LYS A 1 202 ? 179.174 151.135 181.268 1.00 91.06  ? 372 LYS A CE  1 
ATOM 1559 N NZ  . LYS A 1 202 ? 180.177 150.050 181.550 1.00 90.78  ? 372 LYS A NZ  1 
ATOM 1560 N N   . GLU A 1 203 ? 175.624 155.052 185.788 1.00 86.80  ? 373 GLU A N   1 
ATOM 1561 C CA  . GLU A 1 203 ? 174.453 155.118 186.661 1.00 86.31  ? 373 GLU A CA  1 
ATOM 1562 C C   . GLU A 1 203 ? 173.585 156.346 186.427 1.00 85.52  ? 373 GLU A C   1 
ATOM 1563 O O   . GLU A 1 203 ? 172.376 156.198 186.253 1.00 85.77  ? 373 GLU A O   1 
ATOM 1564 C CB  . GLU A 1 203 ? 174.861 155.033 188.135 1.00 86.36  ? 373 GLU A CB  1 
ATOM 1565 C CG  . GLU A 1 203 ? 175.058 153.612 188.623 1.00 87.78  ? 373 GLU A CG  1 
ATOM 1566 C CD  . GLU A 1 203 ? 174.686 153.440 190.095 1.00 89.57  ? 373 GLU A CD  1 
ATOM 1567 O OE1 . GLU A 1 203 ? 173.604 153.930 190.501 1.00 90.75  ? 373 GLU A OE1 1 
ATOM 1568 O OE2 . GLU A 1 203 ? 175.468 152.811 190.843 1.00 88.93  ? 373 GLU A OE2 1 
ATOM 1569 N N   . LYS A 1 204 ? 174.190 157.539 186.430 1.00 84.43  ? 374 LYS A N   1 
ATOM 1570 C CA  . LYS A 1 204 ? 173.446 158.779 186.204 1.00 83.77  ? 374 LYS A CA  1 
ATOM 1571 C C   . LYS A 1 204 ? 172.815 158.724 184.818 1.00 83.31  ? 374 LYS A C   1 
ATOM 1572 O O   . LYS A 1 204 ? 171.595 158.742 184.675 1.00 83.04  ? 374 LYS A O   1 
ATOM 1573 C CB  . LYS A 1 204 ? 174.351 160.008 186.289 1.00 83.51  ? 374 LYS A CB  1 
ATOM 1574 C CG  . LYS A 1 204 ? 174.460 160.657 187.637 1.00 84.07  ? 374 LYS A CG  1 
ATOM 1575 C CD  . LYS A 1 204 ? 173.130 161.093 188.230 1.00 84.85  ? 374 LYS A CD  1 
ATOM 1576 C CE  . LYS A 1 204 ? 173.332 161.439 189.706 1.00 85.30  ? 374 LYS A CE  1 
ATOM 1577 N NZ  . LYS A 1 204 ? 172.083 161.441 190.509 1.00 85.63  ? 374 LYS A NZ  1 
ATOM 1578 N N   . ASP A 1 205 ? 173.676 158.626 183.813 1.00 82.82  ? 375 ASP A N   1 
ATOM 1579 C CA  . ASP A 1 205 ? 173.281 158.559 182.431 1.00 82.93  ? 375 ASP A CA  1 
ATOM 1580 C C   . ASP A 1 205 ? 171.999 157.754 182.227 1.00 82.41  ? 375 ASP A C   1 
ATOM 1581 O O   . ASP A 1 205 ? 171.020 158.269 181.688 1.00 82.29  ? 375 ASP A O   1 
ATOM 1582 C CB  . ASP A 1 205 ? 174.428 157.978 181.606 1.00 83.30  ? 375 ASP A CB  1 
ATOM 1583 C CG  . ASP A 1 205 ? 174.406 158.440 180.158 1.00 85.02  ? 375 ASP A CG  1 
ATOM 1584 O OD1 . ASP A 1 205 ? 173.483 159.208 179.757 1.00 86.60  ? 375 ASP A OD1 1 
ATOM 1585 O OD2 . ASP A 1 205 ? 175.329 158.023 179.417 1.00 87.12  ? 375 ASP A OD2 1 
ATOM 1586 N N   . GLU A 1 206 ? 172.000 156.507 182.686 1.00 81.99  ? 376 GLU A N   1 
ATOM 1587 C CA  . GLU A 1 206 ? 170.835 155.630 182.554 1.00 81.78  ? 376 GLU A CA  1 
ATOM 1588 C C   . GLU A 1 206 ? 169.614 156.144 183.320 1.00 80.94  ? 376 GLU A C   1 
ATOM 1589 O O   . GLU A 1 206 ? 168.517 156.207 182.759 1.00 80.91  ? 376 GLU A O   1 
ATOM 1590 C CB  . GLU A 1 206 ? 171.177 154.188 182.966 1.00 81.90  ? 376 GLU A CB  1 
ATOM 1591 C CG  . GLU A 1 206 ? 172.183 153.497 182.036 1.00 82.46  ? 376 GLU A CG  1 
ATOM 1592 C CD  . GLU A 1 206 ? 172.337 152.000 182.300 1.00 82.80  ? 376 GLU A CD  1 
ATOM 1593 O OE1 . GLU A 1 206 ? 172.400 151.577 183.480 1.00 82.50  ? 376 GLU A OE1 1 
ATOM 1594 O OE2 . GLU A 1 206 ? 172.409 151.245 181.304 1.00 85.09  ? 376 GLU A OE2 1 
ATOM 1595 N N   . MET A 1 207 ? 169.809 156.515 184.586 1.00 79.84  ? 377 MET A N   1 
ATOM 1596 C CA  . MET A 1 207 ? 168.713 157.028 185.418 1.00 79.47  ? 377 MET A CA  1 
ATOM 1597 C C   . MET A 1 207 ? 168.041 158.257 184.786 1.00 77.85  ? 377 MET A C   1 
ATOM 1598 O O   . MET A 1 207 ? 166.817 158.321 184.709 1.00 77.48  ? 377 MET A O   1 
ATOM 1599 C CB  . MET A 1 207 ? 169.177 157.330 186.861 1.00 79.21  ? 377 MET A CB  1 
ATOM 1600 C CG  . MET A 1 207 ? 169.259 156.112 187.800 1.00 79.77  ? 377 MET A CG  1 
ATOM 1601 S SD  . MET A 1 207 ? 169.916 156.544 189.459 1.00 82.50  ? 377 MET A SD  1 
ATOM 1602 C CE  . MET A 1 207 ? 169.686 155.051 190.459 1.00 80.23  ? 377 MET A CE  1 
ATOM 1603 N N   . VAL A 1 208 ? 168.847 159.217 184.336 1.00 76.42  ? 378 VAL A N   1 
ATOM 1604 C CA  . VAL A 1 208 ? 168.336 160.442 183.725 1.00 75.25  ? 378 VAL A CA  1 
ATOM 1605 C C   . VAL A 1 208 ? 167.626 160.156 182.405 1.00 75.08  ? 378 VAL A C   1 
ATOM 1606 O O   . VAL A 1 208 ? 166.586 160.746 182.120 1.00 74.79  ? 378 VAL A O   1 
ATOM 1607 C CB  . VAL A 1 208 ? 169.434 161.516 183.535 1.00 75.08  ? 378 VAL A CB  1 
ATOM 1608 C CG1 . VAL A 1 208 ? 168.858 162.766 182.914 1.00 73.89  ? 378 VAL A CG1 1 
ATOM 1609 C CG2 . VAL A 1 208 ? 170.059 161.869 184.855 1.00 74.04  ? 378 VAL A CG2 1 
ATOM 1610 N N   . GLU A 1 209 ? 168.176 159.236 181.613 1.00 74.81  ? 379 GLU A N   1 
ATOM 1611 C CA  . GLU A 1 209 ? 167.557 158.890 180.342 1.00 74.73  ? 379 GLU A CA  1 
ATOM 1612 C C   . GLU A 1 209 ? 166.210 158.224 180.575 1.00 73.90  ? 379 GLU A C   1 
ATOM 1613 O O   . GLU A 1 209 ? 165.255 158.479 179.845 1.00 73.78  ? 379 GLU A O   1 
ATOM 1614 C CB  . GLU A 1 209 ? 168.453 158.005 179.471 1.00 74.51  ? 379 GLU A CB  1 
ATOM 1615 C CG  . GLU A 1 209 ? 168.073 158.103 177.983 1.00 76.32  ? 379 GLU A CG  1 
ATOM 1616 C CD  . GLU A 1 209 ? 168.686 157.027 177.091 1.00 76.36  ? 379 GLU A CD  1 
ATOM 1617 O OE1 . GLU A 1 209 ? 169.486 156.206 177.585 1.00 78.84  ? 379 GLU A OE1 1 
ATOM 1618 O OE2 . GLU A 1 209 ? 168.345 157.004 175.887 1.00 78.64  ? 379 GLU A OE2 1 
ATOM 1619 N N   . GLN A 1 210 ? 166.134 157.387 181.605 1.00 73.31  ? 380 GLN A N   1 
ATOM 1620 C CA  . GLN A 1 210 ? 164.894 156.704 181.928 1.00 73.29  ? 380 GLN A CA  1 
ATOM 1621 C C   . GLN A 1 210 ? 163.859 157.745 182.331 1.00 72.20  ? 380 GLN A C   1 
ATOM 1622 O O   . GLN A 1 210 ? 162.715 157.689 181.885 1.00 72.56  ? 380 GLN A O   1 
ATOM 1623 C CB  . GLN A 1 210 ? 165.103 155.658 183.027 1.00 73.36  ? 380 GLN A CB  1 
ATOM 1624 C CG  . GLN A 1 210 ? 163.823 154.959 183.492 1.00 74.85  ? 380 GLN A CG  1 
ATOM 1625 C CD  . GLN A 1 210 ? 164.074 153.912 184.570 1.00 75.44  ? 380 GLN A CD  1 
ATOM 1626 O OE1 . GLN A 1 210 ? 163.682 154.077 185.740 1.00 77.52  ? 380 GLN A OE1 1 
ATOM 1627 N NE2 . GLN A 1 210 ? 164.741 152.822 184.183 1.00 78.58  ? 380 GLN A NE2 1 
ATOM 1628 N N   . GLU A 1 211 ? 164.282 158.716 183.136 1.00 71.01  ? 381 GLU A N   1 
ATOM 1629 C CA  . GLU A 1 211 ? 163.402 159.790 183.576 1.00 70.17  ? 381 GLU A CA  1 
ATOM 1630 C C   . GLU A 1 211 ? 162.933 160.616 182.376 1.00 69.45  ? 381 GLU A C   1 
ATOM 1631 O O   . GLU A 1 211 ? 161.752 160.960 182.276 1.00 69.24  ? 381 GLU A O   1 
ATOM 1632 C CB  . GLU A 1 211 ? 164.105 160.674 184.597 1.00 70.40  ? 381 GLU A CB  1 
ATOM 1633 C CG  . GLU A 1 211 ? 163.168 161.519 185.431 1.00 71.61  ? 381 GLU A CG  1 
ATOM 1634 C CD  . GLU A 1 211 ? 162.150 160.702 186.211 1.00 73.59  ? 381 GLU A CD  1 
ATOM 1635 O OE1 . GLU A 1 211 ? 162.434 159.537 186.560 1.00 74.67  ? 381 GLU A OE1 1 
ATOM 1636 O OE2 . GLU A 1 211 ? 161.055 161.231 186.482 1.00 75.13  ? 381 GLU A OE2 1 
ATOM 1637 N N   . PHE A 1 212 ? 163.855 160.900 181.456 1.00 68.32  ? 382 PHE A N   1 
ATOM 1638 C CA  . PHE A 1 212 ? 163.536 161.653 180.262 1.00 67.43  ? 382 PHE A CA  1 
ATOM 1639 C C   . PHE A 1 212 ? 162.418 160.935 179.512 1.00 67.51  ? 382 PHE A C   1 
ATOM 1640 O O   . PHE A 1 212 ? 161.435 161.558 179.089 1.00 67.56  ? 382 PHE A O   1 
ATOM 1641 C CB  . PHE A 1 212 ? 164.773 161.827 179.376 1.00 67.16  ? 382 PHE A CB  1 
ATOM 1642 C CG  . PHE A 1 212 ? 164.463 162.251 177.945 1.00 65.83  ? 382 PHE A CG  1 
ATOM 1643 C CD1 . PHE A 1 212 ? 163.975 163.522 177.664 1.00 65.49  ? 382 PHE A CD1 1 
ATOM 1644 C CD2 . PHE A 1 212 ? 164.685 161.375 176.883 1.00 64.87  ? 382 PHE A CD2 1 
ATOM 1645 C CE1 . PHE A 1 212 ? 163.693 163.914 176.349 1.00 64.51  ? 382 PHE A CE1 1 
ATOM 1646 C CE2 . PHE A 1 212 ? 164.405 161.742 175.572 1.00 63.34  ? 382 PHE A CE2 1 
ATOM 1647 C CZ  . PHE A 1 212 ? 163.907 163.017 175.302 1.00 64.91  ? 382 PHE A CZ  1 
ATOM 1648 N N   . ASN A 1 213 ? 162.555 159.618 179.370 1.00 66.89  ? 383 ASN A N   1 
ATOM 1649 C CA  . ASN A 1 213 ? 161.537 158.834 178.676 1.00 66.12  ? 383 ASN A CA  1 
ATOM 1650 C C   . ASN A 1 213 ? 160.252 158.808 179.482 1.00 65.12  ? 383 ASN A C   1 
ATOM 1651 O O   . ASN A 1 213 ? 159.160 158.902 178.923 1.00 65.54  ? 383 ASN A O   1 
ATOM 1652 C CB  . ASN A 1 213 ? 162.038 157.421 178.367 1.00 66.25  ? 383 ASN A CB  1 
ATOM 1653 C CG  . ASN A 1 213 ? 163.068 157.411 177.256 1.00 66.57  ? 383 ASN A CG  1 
ATOM 1654 O OD1 . ASN A 1 213 ? 162.975 158.175 176.298 1.00 68.82  ? 383 ASN A OD1 1 
ATOM 1655 N ND2 . ASN A 1 213 ? 164.055 156.557 177.381 1.00 67.77  ? 383 ASN A ND2 1 
ATOM 1656 N N   . ARG A 1 214 ? 160.384 158.725 180.796 1.00 63.32  ? 384 ARG A N   1 
ATOM 1657 C CA  . ARG A 1 214 ? 159.216 158.725 181.652 1.00 61.99  ? 384 ARG A CA  1 
ATOM 1658 C C   . ARG A 1 214 ? 158.463 160.051 181.492 1.00 60.92  ? 384 ARG A C   1 
ATOM 1659 O O   . ARG A 1 214 ? 157.235 160.068 181.375 1.00 61.42  ? 384 ARG A O   1 
ATOM 1660 C CB  . ARG A 1 214 ? 159.628 158.473 183.089 1.00 62.11  ? 384 ARG A CB  1 
ATOM 1661 C CG  . ARG A 1 214 ? 159.917 157.016 183.374 1.00 63.03  ? 384 ARG A CG  1 
ATOM 1662 C CD  . ARG A 1 214 ? 160.756 156.824 184.635 1.00 65.89  ? 384 ARG A CD  1 
ATOM 1663 N NE  . ARG A 1 214 ? 160.115 157.392 185.816 1.00 67.92  ? 384 ARG A NE  1 
ATOM 1664 C CZ  . ARG A 1 214 ? 159.097 156.830 186.461 1.00 69.58  ? 384 ARG A CZ  1 
ATOM 1665 N NH1 . ARG A 1 214 ? 158.595 155.674 186.037 1.00 69.59  ? 384 ARG A NH1 1 
ATOM 1666 N NH2 . ARG A 1 214 ? 158.572 157.433 187.531 1.00 69.96  ? 384 ARG A NH2 1 
ATOM 1667 N N   . LEU A 1 215 ? 159.200 161.163 181.441 1.00 58.71  ? 385 LEU A N   1 
ATOM 1668 C CA  . LEU A 1 215 ? 158.569 162.462 181.268 1.00 56.11  ? 385 LEU A CA  1 
ATOM 1669 C C   . LEU A 1 215 ? 157.874 162.574 179.903 1.00 53.89  ? 385 LEU A C   1 
ATOM 1670 O O   . LEU A 1 215 ? 156.833 163.224 179.801 1.00 55.40  ? 385 LEU A O   1 
ATOM 1671 C CB  . LEU A 1 215 ? 159.573 163.603 181.465 1.00 56.40  ? 385 LEU A CB  1 
ATOM 1672 C CG  . LEU A 1 215 ? 160.114 163.768 182.880 1.00 57.37  ? 385 LEU A CG  1 
ATOM 1673 C CD1 . LEU A 1 215 ? 161.373 164.613 182.861 1.00 57.80  ? 385 LEU A CD1 1 
ATOM 1674 C CD2 . LEU A 1 215 ? 159.075 164.370 183.818 1.00 58.07  ? 385 LEU A CD2 1 
ATOM 1675 N N   . LEU A 1 216 ? 158.425 161.981 178.851 1.00 49.58  ? 386 LEU A N   1 
ATOM 1676 C CA  . LEU A 1 216 ? 157.752 162.072 177.559 1.00 45.20  ? 386 LEU A CA  1 
ATOM 1677 C C   . LEU A 1 216 ? 156.446 161.309 177.660 1.00 42.81  ? 386 LEU A C   1 
ATOM 1678 O O   . LEU A 1 216 ? 155.400 161.828 177.309 1.00 41.93  ? 386 LEU A O   1 
ATOM 1679 C CB  . LEU A 1 216 ? 158.618 161.528 176.430 1.00 45.10  ? 386 LEU A CB  1 
ATOM 1680 C CG  . LEU A 1 216 ? 159.761 162.425 175.962 1.00 43.65  ? 386 LEU A CG  1 
ATOM 1681 C CD1 . LEU A 1 216 ? 160.580 161.697 174.931 1.00 41.84  ? 386 LEU A CD1 1 
ATOM 1682 C CD2 . LEU A 1 216 ? 159.244 163.743 175.406 1.00 43.27  ? 386 LEU A CD2 1 
ATOM 1683 N N   . GLU A 1 217 ? 156.520 160.090 178.195 1.00 40.20  ? 387 GLU A N   1 
ATOM 1684 C CA  . GLU A 1 217 ? 155.354 159.238 178.405 1.00 37.82  ? 387 GLU A CA  1 
ATOM 1685 C C   . GLU A 1 217 ? 154.300 160.003 179.195 1.00 35.58  ? 387 GLU A C   1 
ATOM 1686 O O   . GLU A 1 217 ? 153.114 159.932 178.884 1.00 35.07  ? 387 GLU A O   1 
ATOM 1687 C CB  . GLU A 1 217 ? 155.746 157.959 179.150 1.00 37.50  ? 387 GLU A CB  1 
ATOM 1688 C CG  . GLU A 1 217 ? 156.081 156.785 178.246 1.00 38.85  ? 387 GLU A CG  1 
ATOM 1689 C CD  . GLU A 1 217 ? 156.749 155.586 178.968 1.00 39.49  ? 387 GLU A CD  1 
ATOM 1690 O OE1 . GLU A 1 217 ? 156.631 155.437 180.221 1.00 39.20  ? 387 GLU A OE1 1 
ATOM 1691 O OE2 . GLU A 1 217 ? 157.386 154.774 178.245 1.00 41.51  ? 387 GLU A OE2 1 
ATOM 1692 N N   . ALA A 1 218 ? 154.749 160.756 180.198 1.00 33.20  ? 388 ALA A N   1 
ATOM 1693 C CA  . ALA A 1 218 ? 153.860 161.550 181.033 1.00 31.33  ? 388 ALA A CA  1 
ATOM 1694 C C   . ALA A 1 218 ? 153.115 162.655 180.278 1.00 30.11  ? 388 ALA A C   1 
ATOM 1695 O O   . ALA A 1 218 ? 151.961 162.938 180.588 1.00 29.86  ? 388 ALA A O   1 
ATOM 1696 C CB  . ALA A 1 218 ? 154.614 162.134 182.204 1.00 31.18  ? 388 ALA A CB  1 
ATOM 1697 N N   . THR A 1 219 ? 153.761 163.290 179.304 1.00 28.68  ? 389 THR A N   1 
ATOM 1698 C CA  . THR A 1 219 ? 153.092 164.352 178.566 1.00 27.65  ? 389 THR A CA  1 
ATOM 1699 C C   . THR A 1 219 ? 152.014 163.768 177.677 1.00 27.17  ? 389 THR A C   1 
ATOM 1700 O O   . THR A 1 219 ? 151.012 164.411 177.400 1.00 26.66  ? 389 THR A O   1 
ATOM 1701 C CB  . THR A 1 219 ? 154.054 165.235 177.745 1.00 27.75  ? 389 THR A CB  1 
ATOM 1702 O OG1 . THR A 1 219 ? 154.759 164.436 176.791 1.00 27.06  ? 389 THR A OG1 1 
ATOM 1703 C CG2 . THR A 1 219 ? 155.036 165.953 178.655 1.00 26.96  ? 389 THR A CG2 1 
ATOM 1704 N N   . SER A 1 220 ? 152.228 162.530 177.255 1.00 27.13  ? 390 SER A N   1 
ATOM 1705 C CA  . SER A 1 220 ? 151.283 161.819 176.411 1.00 27.17  ? 390 SER A CA  1 
ATOM 1706 C C   . SER A 1 220 ? 150.018 161.518 177.223 1.00 27.30  ? 390 SER A C   1 
ATOM 1707 O O   . SER A 1 220 ? 148.905 161.633 176.715 1.00 27.38  ? 390 SER A O   1 
ATOM 1708 C CB  . SER A 1 220 ? 151.918 160.542 175.885 1.00 26.87  ? 390 SER A CB  1 
ATOM 1709 O OG  . SER A 1 220 ? 151.064 159.914 174.966 1.00 26.94  ? 390 SER A OG  1 
ATOM 1710 N N   . TYR A 1 221 ? 150.198 161.165 178.491 1.00 27.41  ? 391 TYR A N   1 
ATOM 1711 C CA  . TYR A 1 221 ? 149.072 160.896 179.373 1.00 28.13  ? 391 TYR A CA  1 
ATOM 1712 C C   . TYR A 1 221 ? 148.316 162.203 179.586 1.00 28.59  ? 391 TYR A C   1 
ATOM 1713 O O   . TYR A 1 221 ? 147.092 162.239 179.511 1.00 29.30  ? 391 TYR A O   1 
ATOM 1714 C CB  . TYR A 1 221 ? 149.549 160.341 180.711 1.00 27.91  ? 391 TYR A CB  1 
ATOM 1715 C CG  . TYR A 1 221 ? 148.474 160.232 181.764 1.00 27.95  ? 391 TYR A CG  1 
ATOM 1716 C CD1 . TYR A 1 221 ? 148.284 161.242 182.698 1.00 28.07  ? 391 TYR A CD1 1 
ATOM 1717 C CD2 . TYR A 1 221 ? 147.661 159.109 181.842 1.00 28.22  ? 391 TYR A CD2 1 
ATOM 1718 C CE1 . TYR A 1 221 ? 147.304 161.142 183.675 1.00 27.97  ? 391 TYR A CE1 1 
ATOM 1719 C CE2 . TYR A 1 221 ? 146.680 158.997 182.820 1.00 27.80  ? 391 TYR A CE2 1 
ATOM 1720 C CZ  . TYR A 1 221 ? 146.505 160.016 183.729 1.00 27.93  ? 391 TYR A CZ  1 
ATOM 1721 O OH  . TYR A 1 221 ? 145.531 159.906 184.701 1.00 28.35  ? 391 TYR A OH  1 
ATOM 1722 N N   . LEU A 1 222 ? 149.062 163.273 179.833 1.00 28.70  ? 392 LEU A N   1 
ATOM 1723 C CA  . LEU A 1 222 ? 148.498 164.593 180.020 1.00 28.53  ? 392 LEU A CA  1 
ATOM 1724 C C   . LEU A 1 222 ? 147.670 165.013 178.813 1.00 28.67  ? 392 LEU A C   1 
ATOM 1725 O O   . LEU A 1 222 ? 146.722 165.759 178.945 1.00 29.03  ? 392 LEU A O   1 
ATOM 1726 C CB  . LEU A 1 222 ? 149.630 165.588 180.164 1.00 28.63  ? 392 LEU A CB  1 
ATOM 1727 C CG  . LEU A 1 222 ? 150.507 165.431 181.382 1.00 28.67  ? 392 LEU A CG  1 
ATOM 1728 C CD1 . LEU A 1 222 ? 151.627 166.415 181.232 1.00 30.12  ? 392 LEU A CD1 1 
ATOM 1729 C CD2 . LEU A 1 222 ? 149.710 165.748 182.605 1.00 29.34  ? 392 LEU A CD2 1 
ATOM 1730 N N   . SER A 1 223 ? 148.035 164.544 177.631 1.00 28.74  ? 393 SER A N   1 
ATOM 1731 C CA  . SER A 1 223 ? 147.318 164.913 176.427 1.00 29.16  ? 393 SER A CA  1 
ATOM 1732 C C   . SER A 1 223 ? 146.089 164.057 176.127 1.00 29.87  ? 393 SER A C   1 
ATOM 1733 O O   . SER A 1 223 ? 145.018 164.595 175.863 1.00 29.84  ? 393 SER A O   1 
ATOM 1734 C CB  . SER A 1 223 ? 148.273 164.910 175.231 1.00 28.82  ? 393 SER A CB  1 
ATOM 1735 O OG  . SER A 1 223 ? 147.584 165.167 174.021 1.00 28.36  ? 393 SER A OG  1 
ATOM 1736 N N   . HIS A 1 224 ? 146.249 162.735 176.150 1.00 30.88  ? 394 HIS A N   1 
ATOM 1737 C CA  . HIS A 1 224 ? 145.154 161.797 175.848 1.00 31.78  ? 394 HIS A CA  1 
ATOM 1738 C C   . HIS A 1 224 ? 144.195 161.468 176.996 1.00 32.53  ? 394 HIS A C   1 
ATOM 1739 O O   . HIS A 1 224 ? 143.087 160.996 176.748 1.00 32.88  ? 394 HIS A O   1 
ATOM 1740 C CB  . HIS A 1 224 ? 145.716 160.481 175.307 1.00 31.55  ? 394 HIS A CB  1 
ATOM 1741 C CG  . HIS A 1 224 ? 146.445 160.622 174.016 1.00 31.82  ? 394 HIS A CG  1 
ATOM 1742 N ND1 . HIS A 1 224 ? 147.806 160.824 173.951 1.00 32.58  ? 394 HIS A ND1 1 
ATOM 1743 C CD2 . HIS A 1 224 ? 146.009 160.584 172.734 1.00 32.48  ? 394 HIS A CD2 1 
ATOM 1744 C CE1 . HIS A 1 224 ? 148.177 160.914 172.685 1.00 32.93  ? 394 HIS A CE1 1 
ATOM 1745 N NE2 . HIS A 1 224 ? 147.105 160.771 171.927 1.00 33.23  ? 394 HIS A NE2 1 
ATOM 1746 N N   . GLN A 1 225 ? 144.606 161.685 178.236 1.00 33.12  ? 395 GLN A N   1 
ATOM 1747 C CA  . GLN A 1 225 ? 143.741 161.347 179.362 1.00 34.37  ? 395 GLN A CA  1 
ATOM 1748 C C   . GLN A 1 225 ? 143.165 162.524 180.133 1.00 35.10  ? 395 GLN A C   1 
ATOM 1749 O O   . GLN A 1 225 ? 142.035 162.444 180.612 1.00 35.73  ? 395 GLN A O   1 
ATOM 1750 C CB  . GLN A 1 225 ? 144.455 160.395 180.329 1.00 34.49  ? 395 GLN A CB  1 
ATOM 1751 C CG  . GLN A 1 225 ? 144.722 159.013 179.748 1.00 34.98  ? 395 GLN A CG  1 
ATOM 1752 C CD  . GLN A 1 225 ? 143.456 158.210 179.528 1.00 35.40  ? 395 GLN A CD  1 
ATOM 1753 O OE1 . GLN A 1 225 ? 143.128 157.864 178.394 1.00 34.38  ? 395 GLN A OE1 1 
ATOM 1754 N NE2 . GLN A 1 225 ? 142.735 157.906 180.617 1.00 35.75  ? 395 GLN A NE2 1 
ATOM 1755 N N   . LEU A 1 226 ? 143.937 163.593 180.293 1.00 35.55  ? 396 LEU A N   1 
ATOM 1756 C CA  . LEU A 1 226 ? 143.453 164.765 181.006 1.00 35.82  ? 396 LEU A CA  1 
ATOM 1757 C C   . LEU A 1 226 ? 143.007 165.834 179.990 1.00 36.23  ? 396 LEU A C   1 
ATOM 1758 O O   . LEU A 1 226 ? 142.469 166.883 180.354 1.00 36.22  ? 396 LEU A O   1 
ATOM 1759 C CB  . LEU A 1 226 ? 144.517 165.281 181.967 1.00 35.56  ? 396 LEU A CB  1 
ATOM 1760 C CG  . LEU A 1 226 ? 145.066 164.268 182.993 1.00 36.26  ? 396 LEU A CG  1 
ATOM 1761 C CD1 . LEU A 1 226 ? 146.175 164.886 183.842 1.00 35.80  ? 396 LEU A CD1 1 
ATOM 1762 C CD2 . LEU A 1 226 ? 143.990 163.670 183.910 1.00 35.97  ? 396 LEU A CD2 1 
ATOM 1763 N N   . ASP A 1 227 ? 143.214 165.531 178.708 1.00 36.91  ? 397 ASP A N   1 
ATOM 1764 C CA  . ASP A 1 227 ? 142.858 166.422 177.594 1.00 37.73  ? 397 ASP A CA  1 
ATOM 1765 C C   . ASP A 1 227 ? 143.379 167.861 177.791 1.00 37.86  ? 397 ASP A C   1 
ATOM 1766 O O   . ASP A 1 227 ? 142.687 168.846 177.506 1.00 38.17  ? 397 ASP A O   1 
ATOM 1767 C CB  . ASP A 1 227 ? 141.342 166.386 177.349 1.00 37.95  ? 397 ASP A CB  1 
ATOM 1768 C CG  . ASP A 1 227 ? 140.959 166.856 175.963 1.00 39.07  ? 397 ASP A CG  1 
ATOM 1769 O OD1 . ASP A 1 227 ? 141.816 167.409 175.234 1.00 40.58  ? 397 ASP A OD1 1 
ATOM 1770 O OD2 . ASP A 1 227 ? 139.782 166.674 175.596 1.00 41.22  ? 397 ASP A OD2 1 
ATOM 1771 N N   . PHE A 1 228 ? 144.611 167.956 178.280 1.00 37.78  ? 398 PHE A N   1 
ATOM 1772 C CA  . PHE A 1 228 ? 145.292 169.218 178.539 1.00 37.66  ? 398 PHE A CA  1 
ATOM 1773 C C   . PHE A 1 228 ? 145.895 169.650 177.212 1.00 37.76  ? 398 PHE A C   1 
ATOM 1774 O O   . PHE A 1 228 ? 147.093 169.532 177.004 1.00 37.84  ? 398 PHE A O   1 
ATOM 1775 C CB  . PHE A 1 228 ? 146.375 168.975 179.601 1.00 37.52  ? 398 PHE A CB  1 
ATOM 1776 C CG  . PHE A 1 228 ? 147.181 170.190 179.974 1.00 37.49  ? 398 PHE A CG  1 
ATOM 1777 C CD1 . PHE A 1 228 ? 146.632 171.195 180.771 1.00 37.55  ? 398 PHE A CD1 1 
ATOM 1778 C CD2 . PHE A 1 228 ? 148.512 170.298 179.580 1.00 36.67  ? 398 PHE A CD2 1 
ATOM 1779 C CE1 . PHE A 1 228 ? 147.390 172.312 181.136 1.00 37.08  ? 398 PHE A CE1 1 
ATOM 1780 C CE2 . PHE A 1 228 ? 149.276 171.410 179.938 1.00 36.72  ? 398 PHE A CE2 1 
ATOM 1781 C CZ  . PHE A 1 228 ? 148.714 172.417 180.716 1.00 36.90  ? 398 PHE A CZ  1 
ATOM 1782 N N   . ASN A 1 229 ? 145.061 170.111 176.289 1.00 37.88  ? 399 ASN A N   1 
ATOM 1783 C CA  . ASN A 1 229 ? 145.579 170.509 174.990 1.00 38.17  ? 399 ASN A CA  1 
ATOM 1784 C C   . ASN A 1 229 ? 145.344 171.960 174.592 1.00 38.03  ? 399 ASN A C   1 
ATOM 1785 O O   . ASN A 1 229 ? 145.808 172.391 173.531 1.00 38.02  ? 399 ASN A O   1 
ATOM 1786 C CB  . ASN A 1 229 ? 145.087 169.553 173.905 1.00 38.72  ? 399 ASN A CB  1 
ATOM 1787 C CG  . ASN A 1 229 ? 145.619 168.145 174.088 1.00 39.75  ? 399 ASN A CG  1 
ATOM 1788 O OD1 . ASN A 1 229 ? 146.797 167.945 174.371 1.00 40.74  ? 399 ASN A OD1 1 
ATOM 1789 N ND2 . ASN A 1 229 ? 144.748 167.161 173.922 1.00 41.97  ? 399 ASN A ND2 1 
ATOM 1790 N N   . VAL A 1 230 ? 144.634 172.703 175.441 1.00 37.78  ? 400 VAL A N   1 
ATOM 1791 C CA  . VAL A 1 230 ? 144.349 174.119 175.210 1.00 37.69  ? 400 VAL A CA  1 
ATOM 1792 C C   . VAL A 1 230 ? 144.468 174.834 176.550 1.00 37.69  ? 400 VAL A C   1 
ATOM 1793 O O   . VAL A 1 230 ? 143.900 174.388 177.541 1.00 37.92  ? 400 VAL A O   1 
ATOM 1794 C CB  . VAL A 1 230 ? 142.943 174.361 174.579 1.00 37.71  ? 400 VAL A CB  1 
ATOM 1795 C CG1 . VAL A 1 230 ? 142.588 175.850 174.580 1.00 37.88  ? 400 VAL A CG1 1 
ATOM 1796 C CG2 . VAL A 1 230 ? 142.869 173.809 173.154 1.00 36.99  ? 400 VAL A CG2 1 
ATOM 1797 N N   . LEU A 1 231 ? 145.225 175.925 176.580 1.00 37.82  ? 401 LEU A N   1 
ATOM 1798 C CA  . LEU A 1 231 ? 145.423 176.700 177.805 1.00 38.05  ? 401 LEU A CA  1 
ATOM 1799 C C   . LEU A 1 231 ? 145.404 178.187 177.476 1.00 38.23  ? 401 LEU A C   1 
ATOM 1800 O O   . LEU A 1 231 ? 146.315 178.691 176.814 1.00 38.67  ? 401 LEU A O   1 
ATOM 1801 C CB  . LEU A 1 231 ? 146.746 176.313 178.452 1.00 37.95  ? 401 LEU A CB  1 
ATOM 1802 C CG  . LEU A 1 231 ? 146.971 176.642 179.921 1.00 38.33  ? 401 LEU A CG  1 
ATOM 1803 C CD1 . LEU A 1 231 ? 145.884 176.030 180.798 1.00 38.81  ? 401 LEU A CD1 1 
ATOM 1804 C CD2 . LEU A 1 231 ? 148.348 176.127 180.330 1.00 38.26  ? 401 LEU A CD2 1 
ATOM 1805 N N   . ASN A 1 232 ? 144.348 178.874 177.925 1.00 38.10  ? 402 ASN A N   1 
ATOM 1806 C CA  . ASN A 1 232 ? 144.148 180.307 177.682 1.00 37.80  ? 402 ASN A CA  1 
ATOM 1807 C C   . ASN A 1 232 ? 143.995 180.564 176.195 1.00 37.48  ? 402 ASN A C   1 
ATOM 1808 O O   . ASN A 1 232 ? 144.683 181.416 175.635 1.00 37.55  ? 402 ASN A O   1 
ATOM 1809 C CB  . ASN A 1 232 ? 145.296 181.161 178.244 1.00 37.95  ? 402 ASN A CB  1 
ATOM 1810 C CG  . ASN A 1 232 ? 145.752 180.707 179.616 1.00 38.98  ? 402 ASN A CG  1 
ATOM 1811 O OD1 . ASN A 1 232 ? 146.839 180.147 179.756 1.00 40.87  ? 402 ASN A OD1 1 
ATOM 1812 N ND2 . ASN A 1 232 ? 144.920 180.929 180.634 1.00 38.74  ? 402 ASN A ND2 1 
ATOM 1813 N N   . ASN A 1 233 ? 143.098 179.803 175.565 1.00 37.16  ? 403 ASN A N   1 
ATOM 1814 C CA  . ASN A 1 233 ? 142.814 179.899 174.117 1.00 36.67  ? 403 ASN A CA  1 
ATOM 1815 C C   . ASN A 1 233 ? 144.010 179.556 173.235 1.00 36.15  ? 403 ASN A C   1 
ATOM 1816 O O   . ASN A 1 233 ? 143.942 179.691 172.008 1.00 36.26  ? 403 ASN A O   1 
ATOM 1817 C CB  . ASN A 1 233 ? 142.290 181.292 173.724 1.00 36.80  ? 403 ASN A CB  1 
ATOM 1818 C CG  . ASN A 1 233 ? 140.898 181.576 174.254 1.00 37.36  ? 403 ASN A CG  1 
ATOM 1819 O OD1 . ASN A 1 233 ? 140.584 181.297 175.413 1.00 37.65  ? 403 ASN A OD1 1 
ATOM 1820 N ND2 . ASN A 1 233 ? 140.061 182.168 173.407 1.00 38.15  ? 403 ASN A ND2 1 
ATOM 1821 N N   . LYS A 1 234 ? 145.106 179.129 173.853 1.00 35.25  ? 404 LYS A N   1 
ATOM 1822 C CA  . LYS A 1 234 ? 146.306 178.795 173.100 1.00 34.77  ? 404 LYS A CA  1 
ATOM 1823 C C   . LYS A 1 234 ? 146.624 177.303 173.134 1.00 32.99  ? 404 LYS A C   1 
ATOM 1824 O O   . LYS A 1 234 ? 146.494 176.670 174.183 1.00 32.97  ? 404 LYS A O   1 
ATOM 1825 C CB  . LYS A 1 234 ? 147.506 179.623 173.586 1.00 35.00  ? 404 LYS A CB  1 
ATOM 1826 C CG  . LYS A 1 234 ? 147.508 181.091 173.089 1.00 36.51  ? 404 LYS A CG  1 
ATOM 1827 C CD  . LYS A 1 234 ? 148.927 181.706 173.037 1.00 36.68  ? 404 LYS A CD  1 
ATOM 1828 C CE  . LYS A 1 234 ? 149.657 181.621 174.394 1.00 39.62  ? 404 LYS A CE  1 
ATOM 1829 N NZ  . LYS A 1 234 ? 149.055 182.529 175.419 1.00 40.48  ? 404 LYS A NZ  1 
ATOM 1830 N N   . PRO A 1 235 ? 147.018 176.740 171.978 1.00 31.38  ? 405 PRO A N   1 
ATOM 1831 C CA  . PRO A 1 235 ? 147.445 175.345 171.905 1.00 30.25  ? 405 PRO A CA  1 
ATOM 1832 C C   . PRO A 1 235 ? 148.653 175.090 172.798 1.00 29.10  ? 405 PRO A C   1 
ATOM 1833 O O   . PRO A 1 235 ? 149.580 175.892 172.838 1.00 29.23  ? 405 PRO A O   1 
ATOM 1834 C CB  . PRO A 1 235 ? 147.816 175.157 170.429 1.00 30.20  ? 405 PRO A CB  1 
ATOM 1835 C CG  . PRO A 1 235 ? 148.007 176.535 169.892 1.00 30.83  ? 405 PRO A CG  1 
ATOM 1836 C CD  . PRO A 1 235 ? 147.065 177.398 170.664 1.00 31.22  ? 405 PRO A CD  1 
ATOM 1837 N N   . VAL A 1 236 ? 148.612 173.988 173.529 1.00 27.70  ? 406 VAL A N   1 
ATOM 1838 C CA  . VAL A 1 236 ? 149.677 173.606 174.433 1.00 26.14  ? 406 VAL A CA  1 
ATOM 1839 C C   . VAL A 1 236 ? 150.817 172.997 173.637 1.00 25.57  ? 406 VAL A C   1 
ATOM 1840 O O   . VAL A 1 236 ? 150.603 172.241 172.677 1.00 25.66  ? 406 VAL A O   1 
ATOM 1841 C CB  . VAL A 1 236 ? 149.157 172.606 175.481 1.00 25.88  ? 406 VAL A CB  1 
ATOM 1842 C CG1 . VAL A 1 236 ? 150.266 172.145 176.407 1.00 25.70  ? 406 VAL A CG1 1 
ATOM 1843 C CG2 . VAL A 1 236 ? 148.053 173.237 176.287 1.00 26.01  ? 406 VAL A CG2 1 
ATOM 1844 N N   . SER A 1 237 ? 152.032 173.343 174.034 1.00 24.76  ? 407 SER A N   1 
ATOM 1845 C CA  . SER A 1 237 ? 153.229 172.833 173.379 1.00 23.94  ? 407 SER A CA  1 
ATOM 1846 C C   . SER A 1 237 ? 153.814 171.725 174.224 1.00 22.80  ? 407 SER A C   1 
ATOM 1847 O O   . SER A 1 237 ? 153.482 171.609 175.411 1.00 22.23  ? 407 SER A O   1 
ATOM 1848 C CB  . SER A 1 237 ? 154.268 173.949 173.252 1.00 24.08  ? 407 SER A CB  1 
ATOM 1849 O OG  . SER A 1 237 ? 154.809 174.264 174.532 1.00 25.83  ? 407 SER A OG  1 
ATOM 1850 N N   . LEU A 1 238 ? 154.707 170.938 173.624 1.00 21.93  ? 408 LEU A N   1 
ATOM 1851 C CA  . LEU A 1 238 ? 155.383 169.861 174.333 1.00 21.47  ? 408 LEU A CA  1 
ATOM 1852 C C   . LEU A 1 238 ? 156.134 170.444 175.520 1.00 21.89  ? 408 LEU A C   1 
ATOM 1853 O O   . LEU A 1 238 ? 156.018 169.940 176.630 1.00 22.32  ? 408 LEU A O   1 
ATOM 1854 C CB  . LEU A 1 238 ? 156.353 169.144 173.410 1.00 21.11  ? 408 LEU A CB  1 
ATOM 1855 C CG  . LEU A 1 238 ? 157.055 167.911 173.979 1.00 19.52  ? 408 LEU A CG  1 
ATOM 1856 C CD1 . LEU A 1 238 ? 156.083 166.990 174.672 1.00 17.94  ? 408 LEU A CD1 1 
ATOM 1857 C CD2 . LEU A 1 238 ? 157.784 167.180 172.870 1.00 15.54  ? 408 LEU A CD2 1 
ATOM 1858 N N   . GLY A 1 239 ? 156.872 171.534 175.280 1.00 22.25  ? 409 GLY A N   1 
ATOM 1859 C CA  . GLY A 1 239 ? 157.631 172.233 176.310 1.00 22.27  ? 409 GLY A CA  1 
ATOM 1860 C C   . GLY A 1 239 ? 156.779 172.519 177.523 1.00 22.87  ? 409 GLY A C   1 
ATOM 1861 O O   . GLY A 1 239 ? 157.137 172.127 178.636 1.00 23.40  ? 409 GLY A O   1 
ATOM 1862 N N   . GLN A 1 240 ? 155.645 173.185 177.314 1.00 23.20  ? 410 GLN A N   1 
ATOM 1863 C CA  . GLN A 1 240 ? 154.720 173.504 178.411 1.00 23.52  ? 410 GLN A CA  1 
ATOM 1864 C C   . GLN A 1 240 ? 154.323 172.270 179.187 1.00 23.11  ? 410 GLN A C   1 
ATOM 1865 O O   . GLN A 1 240 ? 154.351 172.284 180.414 1.00 23.39  ? 410 GLN A O   1 
ATOM 1866 C CB  . GLN A 1 240 ? 153.432 174.106 177.870 1.00 24.06  ? 410 GLN A CB  1 
ATOM 1867 C CG  . GLN A 1 240 ? 153.298 175.573 177.987 1.00 26.45  ? 410 GLN A CG  1 
ATOM 1868 C CD  . GLN A 1 240 ? 152.166 176.098 177.116 1.00 30.52  ? 410 GLN A CD  1 
ATOM 1869 O OE1 . GLN A 1 240 ? 152.134 175.877 175.897 1.00 29.78  ? 410 GLN A OE1 1 
ATOM 1870 N NE2 . GLN A 1 240 ? 151.228 176.798 177.742 1.00 32.77  ? 410 GLN A NE2 1 
ATOM 1871 N N   . ALA A 1 241 ? 153.935 171.210 178.472 1.00 22.51  ? 411 ALA A N   1 
ATOM 1872 C CA  . ALA A 1 241 ? 153.517 169.990 179.118 1.00 22.31  ? 411 ALA A CA  1 
ATOM 1873 C C   . ALA A 1 241 ? 154.630 169.457 179.986 1.00 22.99  ? 411 ALA A C   1 
ATOM 1874 O O   . ALA A 1 241 ? 154.384 169.122 181.142 1.00 23.21  ? 411 ALA A O   1 
ATOM 1875 C CB  . ALA A 1 241 ? 153.089 168.977 178.129 1.00 22.17  ? 411 ALA A CB  1 
ATOM 1876 N N   . LEU A 1 242 ? 155.851 169.396 179.459 1.00 23.54  ? 412 LEU A N   1 
ATOM 1877 C CA  . LEU A 1 242 ? 156.991 168.901 180.246 1.00 24.09  ? 412 LEU A CA  1 
ATOM 1878 C C   . LEU A 1 242 ? 157.207 169.741 181.512 1.00 25.28  ? 412 LEU A C   1 
ATOM 1879 O O   . LEU A 1 242 ? 157.411 169.201 182.605 1.00 26.00  ? 412 LEU A O   1 
ATOM 1880 C CB  . LEU A 1 242 ? 158.256 168.858 179.399 1.00 23.68  ? 412 LEU A CB  1 
ATOM 1881 C CG  . LEU A 1 242 ? 158.317 167.793 178.302 1.00 21.96  ? 412 LEU A CG  1 
ATOM 1882 C CD1 . LEU A 1 242 ? 159.303 168.187 177.245 1.00 19.17  ? 412 LEU A CD1 1 
ATOM 1883 C CD2 . LEU A 1 242 ? 158.682 166.432 178.896 1.00 21.30  ? 412 LEU A CD2 1 
ATOM 1884 N N   . GLU A 1 243 ? 157.112 171.060 181.380 1.00 25.96  ? 413 GLU A N   1 
ATOM 1885 C CA  . GLU A 1 243 ? 157.279 171.944 182.518 1.00 27.12  ? 413 GLU A CA  1 
ATOM 1886 C C   . GLU A 1 243 ? 156.227 171.610 183.580 1.00 27.12  ? 413 GLU A C   1 
ATOM 1887 O O   . GLU A 1 243 ? 156.546 171.548 184.771 1.00 28.58  ? 413 GLU A O   1 
ATOM 1888 C CB  . GLU A 1 243 ? 157.152 173.387 182.066 1.00 26.90  ? 413 GLU A CB  1 
ATOM 1889 C CG  . GLU A 1 243 ? 157.802 174.439 182.937 1.00 28.20  ? 413 GLU A CG  1 
ATOM 1890 C CD  . GLU A 1 243 ? 157.605 175.861 182.356 1.00 29.68  ? 413 GLU A CD  1 
ATOM 1891 O OE1 . GLU A 1 243 ? 157.599 176.014 181.100 1.00 30.95  ? 413 GLU A OE1 1 
ATOM 1892 O OE2 . GLU A 1 243 ? 157.445 176.829 183.154 1.00 33.30  ? 413 GLU A OE2 1 
ATOM 1893 N N   . VAL A 1 244 ? 154.988 171.366 183.164 1.00 26.85  ? 414 VAL A N   1 
ATOM 1894 C CA  . VAL A 1 244 ? 153.919 171.024 184.110 1.00 26.25  ? 414 VAL A CA  1 
ATOM 1895 C C   . VAL A 1 244 ? 154.205 169.698 184.810 1.00 26.28  ? 414 VAL A C   1 
ATOM 1896 O O   . VAL A 1 244 ? 154.076 169.584 186.045 1.00 26.72  ? 414 VAL A O   1 
ATOM 1897 C CB  . VAL A 1 244 ? 152.539 170.934 183.424 1.00 26.35  ? 414 VAL A CB  1 
ATOM 1898 C CG1 . VAL A 1 244 ? 151.530 170.221 184.339 1.00 25.66  ? 414 VAL A CG1 1 
ATOM 1899 C CG2 . VAL A 1 244 ? 152.041 172.319 183.039 1.00 25.42  ? 414 VAL A CG2 1 
ATOM 1900 N N   . VAL A 1 245 ? 154.605 168.701 184.029 1.00 25.77  ? 415 VAL A N   1 
ATOM 1901 C CA  . VAL A 1 245 ? 154.903 167.387 184.573 1.00 25.75  ? 415 VAL A CA  1 
ATOM 1902 C C   . VAL A 1 245 ? 156.025 167.460 185.613 1.00 26.43  ? 415 VAL A C   1 
ATOM 1903 O O   . VAL A 1 245 ? 155.937 166.849 186.688 1.00 26.17  ? 415 VAL A O   1 
ATOM 1904 C CB  . VAL A 1 245 ? 155.265 166.389 183.478 1.00 25.24  ? 415 VAL A CB  1 
ATOM 1905 C CG1 . VAL A 1 245 ? 155.669 165.078 184.089 1.00 24.91  ? 415 VAL A CG1 1 
ATOM 1906 C CG2 . VAL A 1 245 ? 154.091 166.180 182.568 1.00 24.80  ? 415 VAL A CG2 1 
ATOM 1907 N N   . ILE A 1 246 ? 157.065 168.225 185.292 1.00 27.16  ? 416 ILE A N   1 
ATOM 1908 C CA  . ILE A 1 246 ? 158.206 168.382 186.186 1.00 27.64  ? 416 ILE A CA  1 
ATOM 1909 C C   . ILE A 1 246 ? 157.789 169.113 187.454 1.00 28.39  ? 416 ILE A C   1 
ATOM 1910 O O   . ILE A 1 246 ? 158.175 168.727 188.556 1.00 28.27  ? 416 ILE A O   1 
ATOM 1911 C CB  . ILE A 1 246 ? 159.369 169.079 185.478 1.00 27.53  ? 416 ILE A CB  1 
ATOM 1912 C CG1 . ILE A 1 246 ? 159.956 168.124 184.438 1.00 26.66  ? 416 ILE A CG1 1 
ATOM 1913 C CG2 . ILE A 1 246 ? 160.423 169.510 186.479 1.00 26.86  ? 416 ILE A CG2 1 
ATOM 1914 C CD1 . ILE A 1 246 ? 160.948 168.755 183.535 1.00 26.30  ? 416 ILE A CD1 1 
ATOM 1915 N N   . GLN A 1 247 ? 156.965 170.137 187.304 1.00 29.28  ? 417 GLN A N   1 
ATOM 1916 C CA  . GLN A 1 247 ? 156.502 170.861 188.471 1.00 30.60  ? 417 GLN A CA  1 
ATOM 1917 C C   . GLN A 1 247 ? 155.696 169.926 189.370 1.00 31.13  ? 417 GLN A C   1 
ATOM 1918 O O   . GLN A 1 247 ? 155.868 169.930 190.586 1.00 31.57  ? 417 GLN A O   1 
ATOM 1919 C CB  . GLN A 1 247 ? 155.706 172.091 188.060 1.00 30.76  ? 417 GLN A CB  1 
ATOM 1920 C CG  . GLN A 1 247 ? 156.594 173.226 187.554 1.00 32.25  ? 417 GLN A CG  1 
ATOM 1921 C CD  . GLN A 1 247 ? 155.864 174.171 186.624 1.00 34.15  ? 417 GLN A CD  1 
ATOM 1922 O OE1 . GLN A 1 247 ? 154.906 173.783 185.960 1.00 36.88  ? 417 GLN A OE1 1 
ATOM 1923 N NE2 . GLN A 1 247 ? 156.321 175.415 186.561 1.00 33.27  ? 417 GLN A NE2 1 
ATOM 1924 N N   . LEU A 1 248 ? 154.861 169.083 188.769 1.00 31.76  ? 418 LEU A N   1 
ATOM 1925 C CA  . LEU A 1 248 ? 154.057 168.135 189.537 1.00 31.97  ? 418 LEU A CA  1 
ATOM 1926 C C   . LEU A 1 248 ? 154.901 167.106 190.289 1.00 32.34  ? 418 LEU A C   1 
ATOM 1927 O O   . LEU A 1 248 ? 154.513 166.667 191.384 1.00 32.53  ? 418 LEU A O   1 
ATOM 1928 C CB  . LEU A 1 248 ? 153.006 167.466 188.646 1.00 32.27  ? 418 LEU A CB  1 
ATOM 1929 C CG  . LEU A 1 248 ? 151.901 168.361 188.049 1.00 32.45  ? 418 LEU A CG  1 
ATOM 1930 C CD1 . LEU A 1 248 ? 150.997 167.650 187.075 1.00 32.94  ? 418 LEU A CD1 1 
ATOM 1931 C CD2 . LEU A 1 248 ? 151.069 169.020 189.134 1.00 31.75  ? 418 LEU A CD2 1 
ATOM 1932 N N   . GLN A 1 249 ? 156.049 166.730 189.717 1.00 32.67  ? 419 GLN A N   1 
ATOM 1933 C CA  . GLN A 1 249 ? 156.956 165.775 190.365 1.00 32.92  ? 419 GLN A CA  1 
ATOM 1934 C C   . GLN A 1 249 ? 157.647 166.484 191.531 1.00 33.73  ? 419 GLN A C   1 
ATOM 1935 O O   . GLN A 1 249 ? 157.897 165.874 192.583 1.00 33.77  ? 419 GLN A O   1 
ATOM 1936 C CB  . GLN A 1 249 ? 157.996 165.217 189.397 1.00 32.81  ? 419 GLN A CB  1 
ATOM 1937 C CG  . GLN A 1 249 ? 157.429 164.474 188.178 1.00 33.07  ? 419 GLN A CG  1 
ATOM 1938 C CD  . GLN A 1 249 ? 156.144 163.731 188.481 1.00 33.44  ? 419 GLN A CD  1 
ATOM 1939 O OE1 . GLN A 1 249 ? 156.143 162.744 189.217 1.00 35.08  ? 419 GLN A OE1 1 
ATOM 1940 N NE2 . GLN A 1 249 ? 155.039 164.213 187.928 1.00 32.79  ? 419 GLN A NE2 1 
ATOM 1941 N N   . GLU A 1 250 ? 157.927 167.780 191.362 1.00 34.22  ? 420 GLU A N   1 
ATOM 1942 C CA  . GLU A 1 250 ? 158.552 168.559 192.425 1.00 35.15  ? 420 GLU A CA  1 
ATOM 1943 C C   . GLU A 1 250 ? 157.544 168.686 193.568 1.00 35.27  ? 420 GLU A C   1 
ATOM 1944 O O   . GLU A 1 250 ? 157.902 168.571 194.751 1.00 35.20  ? 420 GLU A O   1 
ATOM 1945 C CB  . GLU A 1 250 ? 159.014 169.927 191.929 1.00 34.96  ? 420 GLU A CB  1 
ATOM 1946 C CG  . GLU A 1 250 ? 160.258 169.857 191.041 1.00 36.14  ? 420 GLU A CG  1 
ATOM 1947 C CD  . GLU A 1 250 ? 160.591 171.174 190.358 1.00 36.45  ? 420 GLU A CD  1 
ATOM 1948 O OE1 . GLU A 1 250 ? 160.248 172.234 190.916 1.00 39.60  ? 420 GLU A OE1 1 
ATOM 1949 O OE2 . GLU A 1 250 ? 161.206 171.155 189.266 1.00 38.58  ? 420 GLU A OE2 1 
ATOM 1950 N N   . LYS A 1 251 ? 156.278 168.885 193.195 1.00 35.33  ? 421 LYS A N   1 
ATOM 1951 C CA  . LYS A 1 251 ? 155.189 168.995 194.149 1.00 35.14  ? 421 LYS A CA  1 
ATOM 1952 C C   . LYS A 1 251 ? 155.052 167.684 194.913 1.00 35.56  ? 421 LYS A C   1 
ATOM 1953 O O   . LYS A 1 251 ? 154.909 167.688 196.130 1.00 36.07  ? 421 LYS A O   1 
ATOM 1954 C CB  . LYS A 1 251 ? 153.882 169.347 193.442 1.00 34.66  ? 421 LYS A CB  1 
ATOM 1955 C CG  . LYS A 1 251 ? 152.655 169.133 194.284 1.00 34.26  ? 421 LYS A CG  1 
ATOM 1956 C CD  . LYS A 1 251 ? 151.395 169.623 193.607 1.00 33.92  ? 421 LYS A CD  1 
ATOM 1957 C CE  . LYS A 1 251 ? 150.230 169.723 194.596 1.00 34.49  ? 421 LYS A CE  1 
ATOM 1958 N NZ  . LYS A 1 251 ? 149.910 168.429 195.272 1.00 34.11  ? 421 LYS A NZ  1 
ATOM 1959 N N   . HIS A 1 252 ? 155.122 166.560 194.209 1.00 35.81  ? 422 HIS A N   1 
ATOM 1960 C CA  . HIS A 1 252 ? 154.998 165.271 194.866 1.00 36.03  ? 422 HIS A CA  1 
ATOM 1961 C C   . HIS A 1 252 ? 156.120 165.014 195.876 1.00 36.15  ? 422 HIS A C   1 
ATOM 1962 O O   . HIS A 1 252 ? 155.890 164.410 196.926 1.00 36.03  ? 422 HIS A O   1 
ATOM 1963 C CB  . HIS A 1 252 ? 154.942 164.139 193.850 1.00 35.97  ? 422 HIS A CB  1 
ATOM 1964 C CG  . HIS A 1 252 ? 154.939 162.783 194.478 1.00 37.49  ? 422 HIS A CG  1 
ATOM 1965 N ND1 . HIS A 1 252 ? 153.871 162.308 195.209 1.00 38.70  ? 422 HIS A ND1 1 
ATOM 1966 C CD2 . HIS A 1 252 ? 155.885 161.814 194.516 1.00 38.44  ? 422 HIS A CD2 1 
ATOM 1967 C CE1 . HIS A 1 252 ? 154.153 161.096 195.657 1.00 39.24  ? 422 HIS A CE1 1 
ATOM 1968 N NE2 . HIS A 1 252 ? 155.370 160.773 195.252 1.00 39.14  ? 422 HIS A NE2 1 
ATOM 1969 N N   . VAL A 1 253 ? 157.330 165.459 195.551 1.00 36.15  ? 423 VAL A N   1 
ATOM 1970 C CA  . VAL A 1 253 ? 158.471 165.276 196.441 1.00 36.16  ? 423 VAL A CA  1 
ATOM 1971 C C   . VAL A 1 253 ? 158.201 166.032 197.752 1.00 36.05  ? 423 VAL A C   1 
ATOM 1972 O O   . VAL A 1 253 ? 158.454 165.515 198.845 1.00 35.74  ? 423 VAL A O   1 
ATOM 1973 C CB  . VAL A 1 253 ? 159.798 165.694 195.744 1.00 35.93  ? 423 VAL A CB  1 
ATOM 1974 C CG1 . VAL A 1 253 ? 160.888 166.088 196.742 1.00 36.71  ? 423 VAL A CG1 1 
ATOM 1975 C CG2 . VAL A 1 253 ? 160.288 164.565 194.872 1.00 36.88  ? 423 VAL A CG2 1 
ATOM 1976 N N   . LYS A 1 254 ? 157.641 167.231 197.626 1.00 36.21  ? 424 LYS A N   1 
ATOM 1977 C CA  . LYS A 1 254 ? 157.310 168.051 198.784 1.00 36.67  ? 424 LYS A CA  1 
ATOM 1978 C C   . LYS A 1 254 ? 156.088 167.513 199.520 1.00 36.82  ? 424 LYS A C   1 
ATOM 1979 O O   . LYS A 1 254 ? 156.020 167.615 200.739 1.00 36.64  ? 424 LYS A O   1 
ATOM 1980 C CB  . LYS A 1 254 ? 157.150 169.521 198.400 1.00 36.54  ? 424 LYS A CB  1 
ATOM 1981 C CG  . LYS A 1 254 ? 158.476 170.199 198.069 1.00 37.20  ? 424 LYS A CG  1 
ATOM 1982 C CD  . LYS A 1 254 ? 158.269 171.616 197.567 1.00 38.40  ? 424 LYS A CD  1 
ATOM 1983 C CE  . LYS A 1 254 ? 159.346 172.012 196.564 1.00 39.18  ? 424 LYS A CE  1 
ATOM 1984 N NZ  . LYS A 1 254 ? 160.528 172.591 197.241 1.00 40.89  ? 424 LYS A NZ  1 
ATOM 1985 N N   . ASP A 1 255 ? 155.146 166.908 198.794 1.00 37.15  ? 425 ASP A N   1 
ATOM 1986 C CA  . ASP A 1 255 ? 153.965 166.329 199.432 1.00 37.65  ? 425 ASP A CA  1 
ATOM 1987 C C   . ASP A 1 255 ? 154.383 165.151 200.318 1.00 37.97  ? 425 ASP A C   1 
ATOM 1988 O O   . ASP A 1 255 ? 153.856 164.983 201.422 1.00 38.11  ? 425 ASP A O   1 
ATOM 1989 C CB  . ASP A 1 255 ? 152.912 165.890 198.416 1.00 37.35  ? 425 ASP A CB  1 
ATOM 1990 C CG  . ASP A 1 255 ? 152.149 167.065 197.812 1.00 38.66  ? 425 ASP A CG  1 
ATOM 1991 O OD1 . ASP A 1 255 ? 151.775 166.981 196.614 1.00 41.33  ? 425 ASP A OD1 1 
ATOM 1992 O OD2 . ASP A 1 255 ? 151.931 168.079 198.512 1.00 38.68  ? 425 ASP A OD2 1 
ATOM 1993 N N   . GLU A 1 256 ? 155.346 164.364 199.844 1.00 38.32  ? 426 GLU A N   1 
ATOM 1994 C CA  . GLU A 1 256 ? 155.854 163.212 200.585 1.00 38.87  ? 426 GLU A CA  1 
ATOM 1995 C C   . GLU A 1 256 ? 156.690 163.643 201.785 1.00 38.68  ? 426 GLU A C   1 
ATOM 1996 O O   . GLU A 1 256 ? 156.644 163.000 202.835 1.00 38.83  ? 426 GLU A O   1 
ATOM 1997 C CB  . GLU A 1 256 ? 156.686 162.314 199.678 1.00 39.27  ? 426 GLU A CB  1 
ATOM 1998 C CG  . GLU A 1 256 ? 155.862 161.415 198.763 1.00 42.44  ? 426 GLU A CG  1 
ATOM 1999 C CD  . GLU A 1 256 ? 155.654 160.030 199.338 1.00 47.00  ? 426 GLU A CD  1 
ATOM 2000 O OE1 . GLU A 1 256 ? 154.958 159.892 200.371 1.00 49.32  ? 426 GLU A OE1 1 
ATOM 2001 O OE2 . GLU A 1 256 ? 156.197 159.069 198.753 1.00 49.09  ? 426 GLU A OE2 1 
ATOM 2002 N N   . GLN A 1 257 ? 157.454 164.721 201.634 1.00 38.32  ? 427 GLN A N   1 
ATOM 2003 C CA  . GLN A 1 257 ? 158.274 165.213 202.725 1.00 38.16  ? 427 GLN A CA  1 
ATOM 2004 C C   . GLN A 1 257 ? 157.356 165.635 203.863 1.00 38.30  ? 427 GLN A C   1 
ATOM 2005 O O   . GLN A 1 257 ? 157.581 165.283 205.021 1.00 38.28  ? 427 GLN A O   1 
ATOM 2006 C CB  . GLN A 1 257 ? 159.137 166.382 202.271 1.00 37.99  ? 427 GLN A CB  1 
ATOM 2007 C CG  . GLN A 1 257 ? 160.485 165.975 201.737 1.00 38.00  ? 427 GLN A CG  1 
ATOM 2008 C CD  . GLN A 1 257 ? 161.194 167.127 201.040 1.00 39.85  ? 427 GLN A CD  1 
ATOM 2009 O OE1 . GLN A 1 257 ? 160.590 168.160 200.749 1.00 41.58  ? 427 GLN A OE1 1 
ATOM 2010 N NE2 . GLN A 1 257 ? 162.486 166.955 200.756 1.00 41.06  ? 427 GLN A NE2 1 
ATOM 2011 N N   . ILE A 1 258 ? 156.298 166.355 203.506 1.00 38.51  ? 428 ILE A N   1 
ATOM 2012 C CA  . ILE A 1 258 ? 155.312 166.825 204.461 1.00 38.63  ? 428 ILE A CA  1 
ATOM 2013 C C   . ILE A 1 258 ? 154.669 165.648 205.194 1.00 39.32  ? 428 ILE A C   1 
ATOM 2014 O O   . ILE A 1 258 ? 154.676 165.616 206.427 1.00 39.36  ? 428 ILE A O   1 
ATOM 2015 C CB  . ILE A 1 258 ? 154.257 167.739 203.785 1.00 38.50  ? 428 ILE A CB  1 
ATOM 2016 C CG1 . ILE A 1 258 ? 154.895 169.084 203.421 1.00 38.04  ? 428 ILE A CG1 1 
ATOM 2017 C CG2 . ILE A 1 258 ? 153.034 167.936 204.693 1.00 38.19  ? 428 ILE A CG2 1 
ATOM 2018 C CD1 . ILE A 1 258 ? 154.028 169.988 202.570 1.00 38.19  ? 428 ILE A CD1 1 
ATOM 2019 N N   . GLU A 1 259 ? 154.147 164.666 204.455 1.00 39.94  ? 429 GLU A N   1 
ATOM 2020 C CA  . GLU A 1 259 ? 153.521 163.525 205.124 1.00 40.79  ? 429 GLU A CA  1 
ATOM 2021 C C   . GLU A 1 259 ? 154.507 162.746 206.006 1.00 40.31  ? 429 GLU A C   1 
ATOM 2022 O O   . GLU A 1 259 ? 154.105 162.177 207.015 1.00 40.51  ? 429 GLU A O   1 
ATOM 2023 C CB  . GLU A 1 259 ? 152.705 162.625 204.174 1.00 41.07  ? 429 GLU A CB  1 
ATOM 2024 C CG  . GLU A 1 259 ? 151.454 163.244 203.576 1.00 44.68  ? 429 GLU A CG  1 
ATOM 2025 C CD  . GLU A 1 259 ? 150.733 162.314 202.583 1.00 48.84  ? 429 GLU A CD  1 
ATOM 2026 O OE1 . GLU A 1 259 ? 151.315 161.262 202.220 1.00 50.92  ? 429 GLU A OE1 1 
ATOM 2027 O OE2 . GLU A 1 259 ? 149.600 162.644 202.147 1.00 49.79  ? 429 GLU A OE2 1 
ATOM 2028 N N   . HIS A 1 260 ? 155.794 162.763 205.653 1.00 39.81  ? 430 HIS A N   1 
ATOM 2029 C CA  . HIS A 1 260 ? 156.802 162.074 206.450 1.00 39.30  ? 430 HIS A CA  1 
ATOM 2030 C C   . HIS A 1 260 ? 157.013 162.816 207.768 1.00 39.55  ? 430 HIS A C   1 
ATOM 2031 O O   . HIS A 1 260 ? 156.979 162.209 208.835 1.00 39.35  ? 430 HIS A O   1 
ATOM 2032 C CB  . HIS A 1 260 ? 158.124 161.916 205.691 1.00 38.87  ? 430 HIS A CB  1 
ATOM 2033 C CG  . HIS A 1 260 ? 159.221 161.304 206.509 1.00 37.87  ? 430 HIS A CG  1 
ATOM 2034 N ND1 . HIS A 1 260 ? 160.203 162.057 207.121 1.00 37.28  ? 430 HIS A ND1 1 
ATOM 2035 C CD2 . HIS A 1 260 ? 159.482 160.014 206.832 1.00 37.15  ? 430 HIS A CD2 1 
ATOM 2036 C CE1 . HIS A 1 260 ? 161.025 161.258 207.780 1.00 36.12  ? 430 HIS A CE1 1 
ATOM 2037 N NE2 . HIS A 1 260 ? 160.608 160.015 207.622 1.00 36.87  ? 430 HIS A NE2 1 
ATOM 2038 N N   . TRP A 1 261 ? 157.208 164.132 207.699 1.00 39.93  ? 431 TRP A N   1 
ATOM 2039 C CA  . TRP A 1 261 ? 157.408 164.915 208.918 1.00 40.36  ? 431 TRP A CA  1 
ATOM 2040 C C   . TRP A 1 261 ? 156.137 165.004 209.764 1.00 40.43  ? 431 TRP A C   1 
ATOM 2041 O O   . TRP A 1 261 ? 156.220 165.202 210.971 1.00 40.87  ? 431 TRP A O   1 
ATOM 2042 C CB  . TRP A 1 261 ? 157.998 166.298 208.632 1.00 40.63  ? 431 TRP A CB  1 
ATOM 2043 C CG  . TRP A 1 261 ? 159.361 166.246 208.011 1.00 41.15  ? 431 TRP A CG  1 
ATOM 2044 C CD1 . TRP A 1 261 ? 159.678 166.561 206.719 1.00 42.53  ? 431 TRP A CD1 1 
ATOM 2045 C CD2 . TRP A 1 261 ? 160.588 165.841 208.634 1.00 40.94  ? 431 TRP A CD2 1 
ATOM 2046 N NE1 . TRP A 1 261 ? 161.022 166.373 206.497 1.00 43.33  ? 431 TRP A NE1 1 
ATOM 2047 C CE2 . TRP A 1 261 ? 161.605 165.933 207.657 1.00 42.08  ? 431 TRP A CE2 1 
ATOM 2048 C CE3 . TRP A 1 261 ? 160.927 165.409 209.918 1.00 41.70  ? 431 TRP A CE3 1 
ATOM 2049 C CZ2 . TRP A 1 261 ? 162.940 165.615 207.926 1.00 41.73  ? 431 TRP A CZ2 1 
ATOM 2050 C CZ3 . TRP A 1 261 ? 162.260 165.095 210.193 1.00 42.24  ? 431 TRP A CZ3 1 
ATOM 2051 C CH2 . TRP A 1 261 ? 163.248 165.202 209.199 1.00 42.10  ? 431 TRP A CH2 1 
ATOM 2052 N N   . LYS A 1 262 ? 154.972 164.821 209.145 1.00 40.37  ? 432 LYS A N   1 
ATOM 2053 C CA  . LYS A 1 262 ? 153.708 164.846 209.877 1.00 40.27  ? 432 LYS A CA  1 
ATOM 2054 C C   . LYS A 1 262 ? 153.519 163.557 210.664 1.00 40.29  ? 432 LYS A C   1 
ATOM 2055 O O   . LYS A 1 262 ? 152.806 163.545 211.664 1.00 40.55  ? 432 LYS A O   1 
ATOM 2056 C CB  . LYS A 1 262 ? 152.516 165.088 208.957 1.00 40.39  ? 432 LYS A CB  1 
ATOM 2057 C CG  . LYS A 1 262 ? 152.216 166.549 208.749 1.00 40.80  ? 432 LYS A CG  1 
ATOM 2058 C CD  . LYS A 1 262 ? 150.960 166.758 207.934 1.00 42.42  ? 432 LYS A CD  1 
ATOM 2059 C CE  . LYS A 1 262 ? 150.457 168.190 208.101 1.00 44.32  ? 432 LYS A CE  1 
ATOM 2060 N NZ  . LYS A 1 262 ? 149.600 168.615 206.959 1.00 46.13  ? 432 LYS A NZ  1 
ATOM 2061 N N   . LYS A 1 263 ? 154.159 162.478 210.221 1.00 40.28  ? 433 LYS A N   1 
ATOM 2062 C CA  . LYS A 1 263 ? 154.069 161.206 210.925 1.00 40.49  ? 433 LYS A CA  1 
ATOM 2063 C C   . LYS A 1 263 ? 154.960 161.303 212.138 1.00 40.21  ? 433 LYS A C   1 
ATOM 2064 O O   . LYS A 1 263 ? 154.690 160.695 213.169 1.00 40.02  ? 433 LYS A O   1 
ATOM 2065 C CB  . LYS A 1 263 ? 154.527 160.040 210.060 1.00 40.70  ? 433 LYS A CB  1 
ATOM 2066 C CG  . LYS A 1 263 ? 153.440 159.463 209.184 1.00 42.59  ? 433 LYS A CG  1 
ATOM 2067 C CD  . LYS A 1 263 ? 153.944 158.237 208.431 1.00 45.01  ? 433 LYS A CD  1 
ATOM 2068 C CE  . LYS A 1 263 ? 153.300 158.126 207.057 1.00 45.52  ? 433 LYS A CE  1 
ATOM 2069 N NZ  . LYS A 1 263 ? 153.781 156.895 206.387 1.00 46.95  ? 433 LYS A NZ  1 
ATOM 2070 N N   . ILE A 1 264 ? 156.027 162.080 212.006 1.00 40.13  ? 434 ILE A N   1 
ATOM 2071 C CA  . ILE A 1 264 ? 156.947 162.268 213.103 1.00 40.23  ? 434 ILE A CA  1 
ATOM 2072 C C   . ILE A 1 264 ? 156.261 163.079 214.206 1.00 40.80  ? 434 ILE A C   1 
ATOM 2073 O O   . ILE A 1 264 ? 156.256 162.638 215.359 1.00 40.87  ? 434 ILE A O   1 
ATOM 2074 C CB  . ILE A 1 264 ? 158.312 162.834 212.644 1.00 40.16  ? 434 ILE A CB  1 
ATOM 2075 C CG1 . ILE A 1 264 ? 159.024 161.767 211.800 1.00 39.42  ? 434 ILE A CG1 1 
ATOM 2076 C CG2 . ILE A 1 264 ? 159.173 163.245 213.854 1.00 39.28  ? 434 ILE A CG2 1 
ATOM 2077 C CD1 . ILE A 1 264 ? 160.417 162.126 211.339 1.00 38.39  ? 434 ILE A CD1 1 
ATOM 2078 N N   . VAL A 1 265 ? 155.634 164.211 213.865 1.00 41.21  ? 435 VAL A N   1 
ATOM 2079 C CA  . VAL A 1 265 ? 154.940 165.001 214.897 1.00 41.90  ? 435 VAL A CA  1 
ATOM 2080 C C   . VAL A 1 265 ? 153.829 164.200 215.556 1.00 42.27  ? 435 VAL A C   1 
ATOM 2081 O O   . VAL A 1 265 ? 153.699 164.231 216.765 1.00 42.28  ? 435 VAL A O   1 
ATOM 2082 C CB  . VAL A 1 265 ? 154.345 166.358 214.413 1.00 41.80  ? 435 VAL A CB  1 
ATOM 2083 C CG1 . VAL A 1 265 ? 155.435 167.312 214.011 1.00 41.95  ? 435 VAL A CG1 1 
ATOM 2084 C CG2 . VAL A 1 265 ? 153.333 166.166 213.294 1.00 41.92  ? 435 VAL A CG2 1 
ATOM 2085 N N   . LYS A 1 266 ? 153.037 163.481 214.761 1.00 42.81  ? 436 LYS A N   1 
ATOM 2086 C CA  . LYS A 1 266 ? 151.953 162.692 215.318 1.00 43.38  ? 436 LYS A CA  1 
ATOM 2087 C C   . LYS A 1 266 ? 152.489 161.741 216.393 1.00 43.32  ? 436 LYS A C   1 
ATOM 2088 O O   . LYS A 1 266 ? 151.933 161.667 217.488 1.00 43.28  ? 436 LYS A O   1 
ATOM 2089 C CB  . LYS A 1 266 ? 151.196 161.942 214.222 1.00 43.53  ? 436 LYS A CB  1 
ATOM 2090 C CG  . LYS A 1 266 ? 149.975 161.182 214.725 1.00 45.71  ? 436 LYS A CG  1 
ATOM 2091 C CD  . LYS A 1 266 ? 149.545 160.086 213.747 1.00 50.52  ? 436 LYS A CD  1 
ATOM 2092 C CE  . LYS A 1 266 ? 148.946 158.869 214.486 1.00 52.36  ? 436 LYS A CE  1 
ATOM 2093 N NZ  . LYS A 1 266 ? 148.641 157.752 213.532 1.00 52.81  ? 436 LYS A NZ  1 
ATOM 2094 N N   . THR A 1 267 ? 153.582 161.044 216.080 1.00 43.46  ? 437 THR A N   1 
ATOM 2095 C CA  . THR A 1 267 ? 154.208 160.106 217.005 1.00 43.57  ? 437 THR A CA  1 
ATOM 2096 C C   . THR A 1 267 ? 154.855 160.870 218.158 1.00 43.93  ? 437 THR A C   1 
ATOM 2097 O O   . THR A 1 267 ? 154.666 160.528 219.329 1.00 43.57  ? 437 THR A O   1 
ATOM 2098 C CB  . THR A 1 267 ? 155.242 159.227 216.282 1.00 43.32  ? 437 THR A CB  1 
ATOM 2099 O OG1 . THR A 1 267 ? 154.576 158.489 215.260 1.00 43.83  ? 437 THR A OG1 1 
ATOM 2100 C CG2 . THR A 1 267 ? 155.886 158.236 217.231 1.00 43.31  ? 437 THR A CG2 1 
ATOM 2101 N N   . GLN A 1 268 ? 155.594 161.917 217.802 1.00 44.32  ? 438 GLN A N   1 
ATOM 2102 C CA  . GLN A 1 268 ? 156.275 162.783 218.747 1.00 44.59  ? 438 GLN A CA  1 
ATOM 2103 C C   . GLN A 1 268 ? 155.229 163.325 219.739 1.00 44.98  ? 438 GLN A C   1 
ATOM 2104 O O   . GLN A 1 268 ? 155.518 163.490 220.930 1.00 45.28  ? 438 GLN A O   1 
ATOM 2105 C CB  . GLN A 1 268 ? 157.001 163.886 217.965 1.00 44.54  ? 438 GLN A CB  1 
ATOM 2106 C CG  . GLN A 1 268 ? 158.184 164.570 218.643 1.00 45.95  ? 438 GLN A CG  1 
ATOM 2107 C CD  . GLN A 1 268 ? 159.407 163.681 218.886 1.00 47.06  ? 438 GLN A CD  1 
ATOM 2108 O OE1 . GLN A 1 268 ? 159.770 163.396 220.044 1.00 47.52  ? 438 GLN A OE1 1 
ATOM 2109 N NE2 . GLN A 1 268 ? 160.071 163.279 217.808 1.00 46.44  ? 438 GLN A NE2 1 
ATOM 2110 N N   . GLU A 1 269 ? 154.001 163.540 219.262 1.00 45.38  ? 439 GLU A N   1 
ATOM 2111 C CA  . GLU A 1 269 ? 152.904 164.024 220.112 1.00 46.04  ? 439 GLU A CA  1 
ATOM 2112 C C   . GLU A 1 269 ? 152.335 162.928 220.999 1.00 46.06  ? 439 GLU A C   1 
ATOM 2113 O O   . GLU A 1 269 ? 152.018 163.189 222.155 1.00 46.25  ? 439 GLU A O   1 
ATOM 2114 C CB  . GLU A 1 269 ? 151.789 164.698 219.312 1.00 45.68  ? 439 GLU A CB  1 
ATOM 2115 C CG  . GLU A 1 269 ? 151.925 166.209 219.277 1.00 46.65  ? 439 GLU A CG  1 
ATOM 2116 C CD  . GLU A 1 269 ? 150.789 166.922 218.540 1.00 47.44  ? 439 GLU A CD  1 
ATOM 2117 O OE1 . GLU A 1 269 ? 150.337 166.441 217.472 1.00 49.01  ? 439 GLU A OE1 1 
ATOM 2118 O OE2 . GLU A 1 269 ? 150.359 167.992 219.029 1.00 49.90  ? 439 GLU A OE2 1 
ATOM 2119 N N   . GLU A 1 270 ? 152.207 161.712 220.470 1.00 46.22  ? 440 GLU A N   1 
ATOM 2120 C CA  . GLU A 1 270 ? 151.699 160.593 221.261 1.00 46.85  ? 440 GLU A CA  1 
ATOM 2121 C C   . GLU A 1 270 ? 152.638 160.370 222.442 1.00 46.33  ? 440 GLU A C   1 
ATOM 2122 O O   . GLU A 1 270 ? 152.204 160.018 223.548 1.00 46.34  ? 440 GLU A O   1 
ATOM 2123 C CB  . GLU A 1 270 ? 151.658 159.310 220.448 1.00 46.63  ? 440 GLU A CB  1 
ATOM 2124 C CG  . GLU A 1 270 ? 150.405 159.077 219.633 1.00 48.33  ? 440 GLU A CG  1 
ATOM 2125 C CD  . GLU A 1 270 ? 150.352 157.640 219.089 1.00 48.93  ? 440 GLU A CD  1 
ATOM 2126 O OE1 . GLU A 1 270 ? 150.291 156.699 219.933 1.00 51.62  ? 440 GLU A OE1 1 
ATOM 2127 O OE2 . GLU A 1 270 ? 150.384 157.454 217.838 1.00 49.56  ? 440 GLU A OE2 1 
ATOM 2128 N N   . LEU A 1 271 ? 153.926 160.580 222.184 1.00 45.87  ? 441 LEU A N   1 
ATOM 2129 C CA  . LEU A 1 271 ? 154.969 160.430 223.175 1.00 45.50  ? 441 LEU A CA  1 
ATOM 2130 C C   . LEU A 1 271 ? 154.760 161.444 224.304 1.00 45.36  ? 441 LEU A C   1 
ATOM 2131 O O   . LEU A 1 271 ? 154.824 161.091 225.478 1.00 45.09  ? 441 LEU A O   1 
ATOM 2132 C CB  . LEU A 1 271 ? 156.339 160.606 222.519 1.00 45.31  ? 441 LEU A CB  1 
ATOM 2133 C CG  . LEU A 1 271 ? 157.562 160.286 223.376 1.00 45.50  ? 441 LEU A CG  1 
ATOM 2134 C CD1 . LEU A 1 271 ? 157.485 158.872 223.929 1.00 45.36  ? 441 LEU A CD1 1 
ATOM 2135 C CD2 . LEU A 1 271 ? 158.845 160.487 222.590 1.00 45.46  ? 441 LEU A CD2 1 
ATOM 2136 N N   . LYS A 1 272 ? 154.483 162.691 223.927 1.00 45.26  ? 442 LYS A N   1 
ATOM 2137 C CA  . LYS A 1 272 ? 154.235 163.776 224.869 1.00 45.01  ? 442 LYS A CA  1 
ATOM 2138 C C   . LYS A 1 272 ? 153.110 163.386 225.818 1.00 45.37  ? 442 LYS A C   1 
ATOM 2139 O O   . LYS A 1 272 ? 153.247 163.520 227.039 1.00 45.68  ? 442 LYS A O   1 
ATOM 2140 C CB  . LYS A 1 272 ? 153.866 165.045 224.107 1.00 44.93  ? 442 LYS A CB  1 
ATOM 2141 C CG  . LYS A 1 272 ? 153.799 166.331 224.905 1.00 44.16  ? 442 LYS A CG  1 
ATOM 2142 C CD  . LYS A 1 272 ? 153.023 167.367 224.104 1.00 44.29  ? 442 LYS A CD  1 
ATOM 2143 C CE  . LYS A 1 272 ? 153.301 168.780 224.565 1.00 45.04  ? 442 LYS A CE  1 
ATOM 2144 N NZ  . LYS A 1 272 ? 153.061 169.756 223.466 1.00 46.05  ? 442 LYS A NZ  1 
ATOM 2145 N N   . GLU A 1 273 ? 152.006 162.889 225.265 1.00 45.43  ? 443 GLU A N   1 
ATOM 2146 C CA  . GLU A 1 273 ? 150.869 162.480 226.085 1.00 45.83  ? 443 GLU A CA  1 
ATOM 2147 C C   . GLU A 1 273 ? 151.215 161.343 227.027 1.00 45.25  ? 443 GLU A C   1 
ATOM 2148 O O   . GLU A 1 273 ? 150.779 161.340 228.180 1.00 45.48  ? 443 GLU A O   1 
ATOM 2149 C CB  . GLU A 1 273 ? 149.667 162.101 225.231 1.00 46.28  ? 443 GLU A CB  1 
ATOM 2150 C CG  . GLU A 1 273 ? 148.705 163.252 224.986 1.00 49.06  ? 443 GLU A CG  1 
ATOM 2151 C CD  . GLU A 1 273 ? 147.469 162.805 224.221 1.00 52.55  ? 443 GLU A CD  1 
ATOM 2152 O OE1 . GLU A 1 273 ? 146.674 162.020 224.794 1.00 54.16  ? 443 GLU A OE1 1 
ATOM 2153 O OE2 . GLU A 1 273 ? 147.301 163.225 223.051 1.00 52.52  ? 443 GLU A OE2 1 
ATOM 2154 N N   . LEU A 1 274 ? 152.003 160.392 226.536 1.00 44.61  ? 444 LEU A N   1 
ATOM 2155 C CA  . LEU A 1 274 ? 152.414 159.255 227.341 1.00 44.25  ? 444 LEU A CA  1 
ATOM 2156 C C   . LEU A 1 274 ? 153.357 159.700 228.458 1.00 43.79  ? 444 LEU A C   1 
ATOM 2157 O O   . LEU A 1 274 ? 153.233 159.256 229.601 1.00 43.59  ? 444 LEU A O   1 
ATOM 2158 C CB  . LEU A 1 274 ? 153.092 158.201 226.475 1.00 44.46  ? 444 LEU A CB  1 
ATOM 2159 C CG  . LEU A 1 274 ? 153.316 156.859 227.172 1.00 45.32  ? 444 LEU A CG  1 
ATOM 2160 C CD1 . LEU A 1 274 ? 152.064 155.994 227.056 1.00 46.49  ? 444 LEU A CD1 1 
ATOM 2161 C CD2 . LEU A 1 274 ? 154.514 156.157 226.560 1.00 45.84  ? 444 LEU A CD2 1 
ATOM 2162 N N   . LEU A 1 275 ? 154.290 160.587 228.122 1.00 43.09  ? 445 LEU A N   1 
ATOM 2163 C CA  . LEU A 1 275 ? 155.238 161.092 229.101 1.00 42.35  ? 445 LEU A CA  1 
ATOM 2164 C C   . LEU A 1 275 ? 154.503 161.859 230.197 1.00 42.25  ? 445 LEU A C   1 
ATOM 2165 O O   . LEU A 1 275 ? 154.808 161.685 231.380 1.00 42.38  ? 445 LEU A O   1 
ATOM 2166 C CB  . LEU A 1 275 ? 156.329 161.930 228.436 1.00 42.07  ? 445 LEU A CB  1 
ATOM 2167 C CG  . LEU A 1 275 ? 157.268 161.160 227.499 1.00 41.16  ? 445 LEU A CG  1 
ATOM 2168 C CD1 . LEU A 1 275 ? 158.216 162.104 226.777 1.00 39.77  ? 445 LEU A CD1 1 
ATOM 2169 C CD2 . LEU A 1 275 ? 158.042 160.079 228.239 1.00 40.32  ? 445 LEU A CD2 1 
ATOM 2170 N N   . ASN A 1 276 ? 153.510 162.663 229.809 1.00 41.94  ? 446 ASN A N   1 
ATOM 2171 C CA  . ASN A 1 276 ? 152.703 163.413 230.774 1.00 41.55  ? 446 ASN A CA  1 
ATOM 2172 C C   . ASN A 1 276 ? 152.037 162.454 231.749 1.00 41.51  ? 446 ASN A C   1 
ATOM 2173 O O   . ASN A 1 276 ? 152.082 162.676 232.954 1.00 41.72  ? 446 ASN A O   1 
ATOM 2174 C CB  . ASN A 1 276 ? 151.646 164.275 230.083 1.00 41.47  ? 446 ASN A CB  1 
ATOM 2175 C CG  . ASN A 1 276 ? 152.129 165.685 229.805 1.00 41.27  ? 446 ASN A CG  1 
ATOM 2176 O OD1 . ASN A 1 276 ? 152.605 166.377 230.697 1.00 39.86  ? 446 ASN A OD1 1 
ATOM 2177 N ND2 . ASN A 1 276 ? 151.996 166.125 228.556 1.00 41.88  ? 446 ASN A ND2 1 
ATOM 2178 N N   . LYS A 1 277 ? 151.446 161.378 231.228 1.00 41.44  ? 447 LYS A N   1 
ATOM 2179 C CA  . LYS A 1 277 ? 150.802 160.378 232.078 1.00 41.69  ? 447 LYS A CA  1 
ATOM 2180 C C   . LYS A 1 277 ? 151.825 159.798 233.036 1.00 41.25  ? 447 LYS A C   1 
ATOM 2181 O O   . LYS A 1 277 ? 151.570 159.706 234.239 1.00 41.54  ? 447 LYS A O   1 
ATOM 2182 C CB  . LYS A 1 277 ? 150.151 159.256 231.257 1.00 41.68  ? 447 LYS A CB  1 
ATOM 2183 C CG  . LYS A 1 277 ? 148.628 159.328 231.211 1.00 42.61  ? 447 LYS A CG  1 
ATOM 2184 C CD  . LYS A 1 277 ? 148.030 158.386 230.167 1.00 42.87  ? 447 LYS A CD  1 
ATOM 2185 C CE  . LYS A 1 277 ? 146.794 159.021 229.492 1.00 44.70  ? 447 LYS A CE  1 
ATOM 2186 N NZ  . LYS A 1 277 ? 146.569 158.546 228.082 1.00 44.28  ? 447 LYS A NZ  1 
ATOM 2187 N N   . MET A 1 278 ? 152.989 159.441 232.499 1.00 40.66  ? 448 MET A N   1 
ATOM 2188 C CA  . MET A 1 278 ? 154.062 158.875 233.301 1.00 40.35  ? 448 MET A CA  1 
ATOM 2189 C C   . MET A 1 278 ? 154.536 159.811 234.417 1.00 40.03  ? 448 MET A C   1 
ATOM 2190 O O   . MET A 1 278 ? 154.733 159.373 235.549 1.00 39.91  ? 448 MET A O   1 
ATOM 2191 C CB  . MET A 1 278 ? 155.227 158.435 232.420 1.00 40.17  ? 448 MET A CB  1 
ATOM 2192 C CG  . MET A 1 278 ? 154.928 157.181 231.623 1.00 40.38  ? 448 MET A CG  1 
ATOM 2193 S SD  . MET A 1 278 ? 156.253 156.672 230.501 1.00 41.02  ? 448 MET A SD  1 
ATOM 2194 C CE  . MET A 1 278 ? 157.445 155.964 231.644 1.00 41.27  ? 448 MET A CE  1 
ATOM 2195 N N   . VAL A 1 279 ? 154.698 161.093 234.107 1.00 39.78  ? 449 VAL A N   1 
ATOM 2196 C CA  . VAL A 1 279 ? 155.143 162.061 235.107 1.00 39.54  ? 449 VAL A CA  1 
ATOM 2197 C C   . VAL A 1 279 ? 154.113 162.198 236.232 1.00 39.77  ? 449 VAL A C   1 
ATOM 2198 O O   . VAL A 1 279 ? 154.482 162.213 237.412 1.00 39.58  ? 449 VAL A O   1 
ATOM 2199 C CB  . VAL A 1 279 ? 155.515 163.421 234.481 1.00 39.34  ? 449 VAL A CB  1 
ATOM 2200 C CG1 . VAL A 1 279 ? 155.591 164.511 235.530 1.00 39.08  ? 449 VAL A CG1 1 
ATOM 2201 C CG2 . VAL A 1 279 ? 156.844 163.309 233.769 1.00 39.44  ? 449 VAL A CG2 1 
ATOM 2202 N N   . ASN A 1 280 ? 152.831 162.249 235.866 1.00 39.88  ? 450 ASN A N   1 
ATOM 2203 C CA  . ASN A 1 280 ? 151.754 162.346 236.853 1.00 39.94  ? 450 ASN A CA  1 
ATOM 2204 C C   . ASN A 1 280 ? 151.648 161.063 237.667 1.00 39.78  ? 450 ASN A C   1 
ATOM 2205 O O   . ASN A 1 280 ? 151.380 161.103 238.869 1.00 39.99  ? 450 ASN A O   1 
ATOM 2206 C CB  . ASN A 1 280 ? 150.417 162.668 236.186 1.00 39.92  ? 450 ASN A CB  1 
ATOM 2207 C CG  . ASN A 1 280 ? 150.334 164.108 235.721 1.00 40.69  ? 450 ASN A CG  1 
ATOM 2208 O OD1 . ASN A 1 280 ? 150.773 165.025 236.420 1.00 41.51  ? 450 ASN A OD1 1 
ATOM 2209 N ND2 . ASN A 1 280 ? 149.773 164.319 234.536 1.00 40.68  ? 450 ASN A ND2 1 
ATOM 2210 N N   . LEU A 1 281 ? 151.882 159.932 237.011 1.00 39.58  ? 451 LEU A N   1 
ATOM 2211 C CA  . LEU A 1 281 ? 151.829 158.644 237.675 1.00 39.48  ? 451 LEU A CA  1 
ATOM 2212 C C   . LEU A 1 281 ? 152.994 158.501 238.655 1.00 39.40  ? 451 LEU A C   1 
ATOM 2213 O O   . LEU A 1 281 ? 152.838 157.923 239.730 1.00 39.52  ? 451 LEU A O   1 
ATOM 2214 C CB  . LEU A 1 281 ? 151.818 157.510 236.654 1.00 39.56  ? 451 LEU A CB  1 
ATOM 2215 C CG  . LEU A 1 281 ? 151.308 156.159 237.159 1.00 40.01  ? 451 LEU A CG  1 
ATOM 2216 C CD1 . LEU A 1 281 ? 149.963 156.286 237.886 1.00 40.50  ? 451 LEU A CD1 1 
ATOM 2217 C CD2 . LEU A 1 281 ? 151.207 155.182 236.006 1.00 40.18  ? 451 LEU A CD2 1 
ATOM 2218 N N   . LYS A 1 282 ? 154.150 159.057 238.298 1.00 39.31  ? 452 LYS A N   1 
ATOM 2219 C CA  . LYS A 1 282 ? 155.308 159.004 239.176 1.00 39.32  ? 452 LYS A CA  1 
ATOM 2220 C C   . LYS A 1 282 ? 155.046 159.851 240.428 1.00 39.47  ? 452 LYS A C   1 
ATOM 2221 O O   . LYS A 1 282 ? 155.502 159.495 241.512 1.00 39.52  ? 452 LYS A O   1 
ATOM 2222 C CB  . LYS A 1 282 ? 156.582 159.453 238.460 1.00 39.34  ? 452 LYS A CB  1 
ATOM 2223 C CG  . LYS A 1 282 ? 157.851 159.127 239.231 1.00 39.59  ? 452 LYS A CG  1 
ATOM 2224 C CD  . LYS A 1 282 ? 159.068 159.753 238.588 1.00 40.28  ? 452 LYS A CD  1 
ATOM 2225 C CE  . LYS A 1 282 ? 160.239 159.778 239.555 1.00 40.38  ? 452 LYS A CE  1 
ATOM 2226 N NZ  . LYS A 1 282 ? 161.338 160.618 239.010 1.00 41.30  ? 452 LYS A NZ  1 
ATOM 2227 N N   . GLU A 1 283 ? 154.294 160.945 240.279 1.00 39.53  ? 453 GLU A N   1 
ATOM 2228 C CA  . GLU A 1 283 ? 153.954 161.798 241.417 1.00 39.87  ? 453 GLU A CA  1 
ATOM 2229 C C   . GLU A 1 283 ? 153.079 160.994 242.365 1.00 39.67  ? 453 GLU A C   1 
ATOM 2230 O O   . GLU A 1 283 ? 153.349 160.945 243.567 1.00 39.60  ? 453 GLU A O   1 
ATOM 2231 C CB  . GLU A 1 283 ? 153.200 163.071 241.008 1.00 40.16  ? 453 GLU A CB  1 
ATOM 2232 C CG  . GLU A 1 283 ? 153.850 163.926 239.912 1.00 42.35  ? 453 GLU A CG  1 
ATOM 2233 C CD  . GLU A 1 283 ? 155.287 164.344 240.220 1.00 44.84  ? 453 GLU A CD  1 
ATOM 2234 O OE1 . GLU A 1 283 ? 155.658 164.408 241.425 1.00 45.78  ? 453 GLU A OE1 1 
ATOM 2235 O OE2 . GLU A 1 283 ? 156.036 164.620 239.245 1.00 44.89  ? 453 GLU A OE2 1 
ATOM 2236 N N   . LYS A 1 284 ? 152.041 160.355 241.817 1.00 39.31  ? 454 LYS A N   1 
ATOM 2237 C CA  . LYS A 1 284 ? 151.125 159.544 242.623 1.00 39.14  ? 454 LYS A CA  1 
ATOM 2238 C C   . LYS A 1 284 ? 151.877 158.431 243.337 1.00 38.34  ? 454 LYS A C   1 
ATOM 2239 O O   . LYS A 1 284 ? 151.651 158.189 244.521 1.00 38.52  ? 454 LYS A O   1 
ATOM 2240 C CB  . LYS A 1 284 ? 149.958 158.990 241.796 1.00 39.08  ? 454 LYS A CB  1 
ATOM 2241 C CG  . LYS A 1 284 ? 148.763 159.949 241.690 1.00 39.84  ? 454 LYS A CG  1 
ATOM 2242 C CD  . LYS A 1 284 ? 147.716 159.442 240.698 1.00 40.26  ? 454 LYS A CD  1 
ATOM 2243 C CE  . LYS A 1 284 ? 147.090 160.591 239.894 1.00 42.31  ? 454 LYS A CE  1 
ATOM 2244 N NZ  . LYS A 1 284 ? 146.929 160.246 238.427 1.00 42.49  ? 454 LYS A NZ  1 
ATOM 2245 N N   . ILE A 1 285 ? 152.793 157.780 242.624 1.00 37.57  ? 455 ILE A N   1 
ATOM 2246 C CA  . ILE A 1 285 ? 153.590 156.707 243.205 1.00 36.70  ? 455 ILE A CA  1 
ATOM 2247 C C   . ILE A 1 285 ? 154.469 157.245 244.334 1.00 36.41  ? 455 ILE A C   1 
ATOM 2248 O O   . ILE A 1 285 ? 154.538 156.647 245.397 1.00 36.53  ? 455 ILE A O   1 
ATOM 2249 C CB  . ILE A 1 285 ? 154.405 155.962 242.135 1.00 36.49  ? 455 ILE A CB  1 
ATOM 2250 C CG1 . ILE A 1 285 ? 153.461 155.094 241.300 1.00 36.26  ? 455 ILE A CG1 1 
ATOM 2251 C CG2 . ILE A 1 285 ? 155.477 155.101 242.779 1.00 36.20  ? 455 ILE A CG2 1 
ATOM 2252 C CD1 . ILE A 1 285 ? 153.971 154.735 239.915 1.00 36.34  ? 455 ILE A CD1 1 
ATOM 2253 N N   . LYS A 1 286 ? 155.095 158.395 244.099 1.00 36.19  ? 456 LYS A N   1 
ATOM 2254 C CA  . LYS A 1 286 ? 155.952 159.075 245.071 1.00 35.90  ? 456 LYS A CA  1 
ATOM 2255 C C   . LYS A 1 286 ? 155.148 159.345 246.359 1.00 35.71  ? 456 LYS A C   1 
ATOM 2256 O O   . LYS A 1 286 ? 155.620 159.111 247.479 1.00 35.57  ? 456 LYS A O   1 
ATOM 2257 C CB  . LYS A 1 286 ? 156.460 160.383 244.441 1.00 36.07  ? 456 LYS A CB  1 
ATOM 2258 C CG  . LYS A 1 286 ? 157.668 161.041 245.092 1.00 37.22  ? 456 LYS A CG  1 
ATOM 2259 C CD  . LYS A 1 286 ? 157.249 162.173 246.034 1.00 39.60  ? 456 LYS A CD  1 
ATOM 2260 C CE  . LYS A 1 286 ? 158.455 162.935 246.601 1.00 40.81  ? 456 LYS A CE  1 
ATOM 2261 N NZ  . LYS A 1 286 ? 158.208 163.412 248.009 1.00 41.01  ? 456 LYS A NZ  1 
ATOM 2262 N N   . GLU A 1 287 ? 153.919 159.815 246.171 1.00 35.43  ? 457 GLU A N   1 
ATOM 2263 C CA  . GLU A 1 287 ? 153.006 160.133 247.254 1.00 35.23  ? 457 GLU A CA  1 
ATOM 2264 C C   . GLU A 1 287 ? 152.532 158.895 248.015 1.00 34.85  ? 457 GLU A C   1 
ATOM 2265 O O   . GLU A 1 287 ? 152.504 158.894 249.257 1.00 35.20  ? 457 GLU A O   1 
ATOM 2266 C CB  . GLU A 1 287 ? 151.816 160.905 246.695 1.00 35.39  ? 457 GLU A CB  1 
ATOM 2267 C CG  . GLU A 1 287 ? 150.838 161.386 247.746 1.00 37.52  ? 457 GLU A CG  1 
ATOM 2268 C CD  . GLU A 1 287 ? 150.194 162.721 247.390 1.00 40.24  ? 457 GLU A CD  1 
ATOM 2269 O OE1 . GLU A 1 287 ? 150.304 163.162 246.211 1.00 39.79  ? 457 GLU A OE1 1 
ATOM 2270 O OE2 . GLU A 1 287 ? 149.586 163.329 248.311 1.00 40.62  ? 457 GLU A OE2 1 
ATOM 2271 N N   . LEU A 1 288 ? 152.153 157.853 247.279 1.00 34.11  ? 458 LEU A N   1 
ATOM 2272 C CA  . LEU A 1 288 ? 151.684 156.618 247.898 1.00 33.56  ? 458 LEU A CA  1 
ATOM 2273 C C   . LEU A 1 288 ? 152.759 155.990 248.742 1.00 33.08  ? 458 LEU A C   1 
ATOM 2274 O O   . LEU A 1 288 ? 152.485 155.521 249.832 1.00 33.07  ? 458 LEU A O   1 
ATOM 2275 C CB  . LEU A 1 288 ? 151.215 155.611 246.852 1.00 33.80  ? 458 LEU A CB  1 
ATOM 2276 C CG  . LEU A 1 288 ? 149.710 155.539 246.604 1.00 34.19  ? 458 LEU A CG  1 
ATOM 2277 C CD1 . LEU A 1 288 ? 149.409 154.488 245.562 1.00 34.02  ? 458 LEU A CD1 1 
ATOM 2278 C CD2 . LEU A 1 288 ? 148.969 155.229 247.902 1.00 34.48  ? 458 LEU A CD2 1 
ATOM 2279 N N   . HIS A 1 289 ? 153.985 155.987 248.234 1.00 32.75  ? 459 HIS A N   1 
ATOM 2280 C CA  . HIS A 1 289 ? 155.116 155.418 248.951 1.00 32.66  ? 459 HIS A CA  1 
ATOM 2281 C C   . HIS A 1 289 ? 155.278 156.097 250.309 1.00 32.74  ? 459 HIS A C   1 
ATOM 2282 O O   . HIS A 1 289 ? 155.479 155.437 251.326 1.00 32.99  ? 459 HIS A O   1 
ATOM 2283 C CB  . HIS A 1 289 ? 156.386 155.584 248.127 1.00 32.40  ? 459 HIS A CB  1 
ATOM 2284 C CG  . HIS A 1 289 ? 157.585 154.915 248.719 1.00 32.14  ? 459 HIS A CG  1 
ATOM 2285 N ND1 . HIS A 1 289 ? 157.948 153.624 248.406 1.00 31.77  ? 459 HIS A ND1 1 
ATOM 2286 C CD2 . HIS A 1 289 ? 158.515 155.366 249.595 1.00 31.80  ? 459 HIS A CD2 1 
ATOM 2287 C CE1 . HIS A 1 289 ? 159.050 153.307 249.059 1.00 31.60  ? 459 HIS A CE1 1 
ATOM 2288 N NE2 . HIS A 1 289 ? 159.411 154.345 249.791 1.00 32.44  ? 459 HIS A NE2 1 
ATOM 2289 N N   . GLN A 1 290 ? 155.164 157.421 250.311 1.00 32.84  ? 460 GLN A N   1 
ATOM 2290 C CA  . GLN A 1 290 ? 155.285 158.212 251.518 1.00 32.82  ? 460 GLN A CA  1 
ATOM 2291 C C   . GLN A 1 290 ? 154.189 157.807 252.499 1.00 32.79  ? 460 GLN A C   1 
ATOM 2292 O O   . GLN A 1 290 ? 154.439 157.648 253.694 1.00 32.63  ? 460 GLN A O   1 
ATOM 2293 C CB  . GLN A 1 290 ? 155.224 159.709 251.176 1.00 32.83  ? 460 GLN A CB  1 
ATOM 2294 C CG  . GLN A 1 290 ? 155.415 160.665 252.361 1.00 34.37  ? 460 GLN A CG  1 
ATOM 2295 C CD  . GLN A 1 290 ? 156.705 160.419 253.157 1.00 36.43  ? 460 GLN A CD  1 
ATOM 2296 O OE1 . GLN A 1 290 ? 157.744 160.064 252.590 1.00 38.53  ? 460 GLN A OE1 1 
ATOM 2297 N NE2 . GLN A 1 290 ? 156.641 160.618 254.473 1.00 34.90  ? 460 GLN A NE2 1 
ATOM 2298 N N   . GLN A 1 291 ? 152.977 157.624 251.986 1.00 32.93  ? 461 GLN A N   1 
ATOM 2299 C CA  . GLN A 1 291 ? 151.853 157.228 252.825 1.00 32.95  ? 461 GLN A CA  1 
ATOM 2300 C C   . GLN A 1 291 ? 152.054 155.823 253.379 1.00 33.01  ? 461 GLN A C   1 
ATOM 2301 O O   . GLN A 1 291 ? 151.791 155.568 254.565 1.00 32.90  ? 461 GLN A O   1 
ATOM 2302 C CB  . GLN A 1 291 ? 150.543 157.353 252.057 1.00 32.85  ? 461 GLN A CB  1 
ATOM 2303 C CG  . GLN A 1 291 ? 150.018 158.778 252.026 1.00 33.40  ? 461 GLN A CG  1 
ATOM 2304 C CD  . GLN A 1 291 ? 149.064 159.032 250.881 1.00 34.33  ? 461 GLN A CD  1 
ATOM 2305 O OE1 . GLN A 1 291 ? 148.374 158.126 250.418 1.00 34.60  ? 461 GLN A OE1 1 
ATOM 2306 N NE2 . GLN A 1 291 ? 149.026 160.273 250.411 1.00 35.32  ? 461 GLN A NE2 1 
ATOM 2307 N N   . TYR A 1 292 ? 152.554 154.926 252.529 1.00 33.05  ? 462 TYR A N   1 
ATOM 2308 C CA  . TYR A 1 292 ? 152.821 153.557 252.930 1.00 33.32  ? 462 TYR A CA  1 
ATOM 2309 C C   . TYR A 1 292 ? 153.875 153.563 254.029 1.00 33.68  ? 462 TYR A C   1 
ATOM 2310 O O   . TYR A 1 292 ? 153.757 152.833 255.012 1.00 33.70  ? 462 TYR A O   1 
ATOM 2311 C CB  . TYR A 1 292 ? 153.295 152.717 251.744 1.00 33.19  ? 462 TYR A CB  1 
ATOM 2312 C CG  . TYR A 1 292 ? 153.792 151.355 252.150 1.00 33.42  ? 462 TYR A CG  1 
ATOM 2313 C CD1 . TYR A 1 292 ? 155.151 151.112 252.329 1.00 33.87  ? 462 TYR A CD1 1 
ATOM 2314 C CD2 . TYR A 1 292 ? 152.902 150.313 252.389 1.00 33.75  ? 462 TYR A CD2 1 
ATOM 2315 C CE1 . TYR A 1 292 ? 155.614 149.860 252.727 1.00 33.95  ? 462 TYR A CE1 1 
ATOM 2316 C CE2 . TYR A 1 292 ? 153.353 149.058 252.786 1.00 34.20  ? 462 TYR A CE2 1 
ATOM 2317 C CZ  . TYR A 1 292 ? 154.708 148.840 252.949 1.00 34.05  ? 462 TYR A CZ  1 
ATOM 2318 O OH  . TYR A 1 292 ? 155.155 147.600 253.328 1.00 34.18  ? 462 TYR A OH  1 
ATOM 2319 N N   . LYS A 1 293 ? 154.895 154.399 253.857 1.00 34.19  ? 463 LYS A N   1 
ATOM 2320 C CA  . LYS A 1 293 ? 155.980 154.521 254.826 1.00 34.66  ? 463 LYS A CA  1 
ATOM 2321 C C   . LYS A 1 293 ? 155.479 155.018 256.183 1.00 34.40  ? 463 LYS A C   1 
ATOM 2322 O O   . LYS A 1 293 ? 155.934 154.551 257.233 1.00 34.48  ? 463 LYS A O   1 
ATOM 2323 C CB  . LYS A 1 293 ? 157.075 155.437 254.277 1.00 35.03  ? 463 LYS A CB  1 
ATOM 2324 C CG  . LYS A 1 293 ? 158.481 154.885 254.459 1.00 37.30  ? 463 LYS A CG  1 
ATOM 2325 C CD  . LYS A 1 293 ? 158.784 153.755 253.464 1.00 40.49  ? 463 LYS A CD  1 
ATOM 2326 C CE  . LYS A 1 293 ? 159.763 152.726 254.055 1.00 42.29  ? 463 LYS A CE  1 
ATOM 2327 N NZ  . LYS A 1 293 ? 160.054 151.642 253.065 1.00 43.50  ? 463 LYS A NZ  1 
ATOM 2328 N N   . GLU A 1 294 ? 154.527 155.948 256.152 1.00 34.22  ? 464 GLU A N   1 
ATOM 2329 C CA  . GLU A 1 294 ? 153.931 156.499 257.366 1.00 34.23  ? 464 GLU A CA  1 
ATOM 2330 C C   . GLU A 1 294 ? 153.044 155.463 258.043 1.00 33.98  ? 464 GLU A C   1 
ATOM 2331 O O   . GLU A 1 294 ? 153.011 155.375 259.263 1.00 34.19  ? 464 GLU A O   1 
ATOM 2332 C CB  . GLU A 1 294 ? 153.117 157.754 257.053 1.00 34.30  ? 464 GLU A CB  1 
ATOM 2333 C CG  . GLU A 1 294 ? 153.913 159.040 257.184 1.00 36.15  ? 464 GLU A CG  1 
ATOM 2334 C CD  . GLU A 1 294 ? 153.550 160.097 256.145 1.00 39.31  ? 464 GLU A CD  1 
ATOM 2335 O OE1 . GLU A 1 294 ? 152.472 160.003 255.509 1.00 41.35  ? 464 GLU A OE1 1 
ATOM 2336 O OE2 . GLU A 1 294 ? 154.360 161.033 255.957 1.00 40.31  ? 464 GLU A OE2 1 
ATOM 2337 N N   . ALA A 1 295 ? 152.325 154.677 257.244 1.00 33.85  ? 465 ALA A N   1 
ATOM 2338 C CA  . ALA A 1 295 ? 151.450 153.649 257.777 1.00 33.39  ? 465 ALA A CA  1 
ATOM 2339 C C   . ALA A 1 295 ? 152.277 152.557 258.440 1.00 33.48  ? 465 ALA A C   1 
ATOM 2340 O O   . ALA A 1 295 ? 151.850 151.981 259.448 1.00 33.13  ? 465 ALA A O   1 
ATOM 2341 C CB  . ALA A 1 295 ? 150.573 153.076 256.691 1.00 33.17  ? 465 ALA A CB  1 
ATOM 2342 N N   . SER A 1 296 ? 153.465 152.300 257.886 1.00 33.67  ? 466 SER A N   1 
ATOM 2343 C CA  . SER A 1 296 ? 154.389 151.295 258.416 1.00 34.19  ? 466 SER A CA  1 
ATOM 2344 C C   . SER A 1 296 ? 155.082 151.733 259.703 1.00 34.33  ? 466 SER A C   1 
ATOM 2345 O O   . SER A 1 296 ? 155.813 150.945 260.303 1.00 34.44  ? 466 SER A O   1 
ATOM 2346 C CB  . SER A 1 296 ? 155.451 150.938 257.384 1.00 34.31  ? 466 SER A CB  1 
ATOM 2347 O OG  . SER A 1 296 ? 154.921 150.103 256.373 1.00 35.80  ? 466 SER A OG  1 
ATOM 2348 N N   . GLU A 1 297 ? 154.864 152.989 260.110 1.00 34.60  ? 467 GLU A N   1 
ATOM 2349 C CA  . GLU A 1 297 ? 155.452 153.546 261.336 1.00 34.55  ? 467 GLU A CA  1 
ATOM 2350 C C   . GLU A 1 297 ? 154.615 153.137 262.528 1.00 34.15  ? 467 GLU A C   1 
ATOM 2351 O O   . GLU A 1 297 ? 155.115 153.105 263.647 1.00 34.48  ? 467 GLU A O   1 
ATOM 2352 C CB  . GLU A 1 297 ? 155.554 155.083 261.305 1.00 34.83  ? 467 GLU A CB  1 
ATOM 2353 C CG  . GLU A 1 297 ? 156.503 155.695 260.245 1.00 36.91  ? 467 GLU A CG  1 
ATOM 2354 C CD  . GLU A 1 297 ? 157.913 155.100 260.252 1.00 38.63  ? 467 GLU A CD  1 
ATOM 2355 O OE1 . GLU A 1 297 ? 158.483 154.905 261.355 1.00 39.10  ? 467 GLU A OE1 1 
ATOM 2356 O OE2 . GLU A 1 297 ? 158.442 154.835 259.143 1.00 39.18  ? 467 GLU A OE2 1 
ATOM 2357 N N   . VAL A 1 298 ? 153.331 152.870 262.293 1.00 33.72  ? 468 VAL A N   1 
ATOM 2358 C CA  . VAL A 1 298 ? 152.420 152.434 263.346 1.00 33.18  ? 468 VAL A CA  1 
ATOM 2359 C C   . VAL A 1 298 ? 152.862 150.996 263.416 1.00 33.29  ? 468 VAL A C   1 
ATOM 2360 O O   . VAL A 1 298 ? 152.515 150.175 262.573 1.00 32.88  ? 468 VAL A O   1 
ATOM 2361 C CB  . VAL A 1 298 ? 150.944 152.577 262.941 1.00 33.13  ? 468 VAL A CB  1 
ATOM 2362 C CG1 . VAL A 1 298 ? 150.034 152.324 264.131 1.00 32.27  ? 468 VAL A CG1 1 
ATOM 2363 C CG2 . VAL A 1 298 ? 150.678 153.969 262.334 1.00 32.52  ? 468 VAL A CG2 1 
ATOM 2364 N N   . LYS A 1 299 ? 153.650 150.685 264.441 1.00 33.72  ? 469 LYS A N   1 
ATOM 2365 C CA  . LYS A 1 299 ? 154.157 149.332 264.636 1.00 34.27  ? 469 LYS A CA  1 
ATOM 2366 C C   . LYS A 1 299 ? 153.169 148.480 265.424 1.00 34.03  ? 469 LYS A C   1 
ATOM 2367 O O   . LYS A 1 299 ? 152.406 148.994 266.241 1.00 35.39  ? 469 LYS A O   1 
ATOM 2368 C CB  . LYS A 1 299 ? 155.511 149.364 265.349 1.00 34.38  ? 469 LYS A CB  1 
ATOM 2369 C CG  . LYS A 1 299 ? 156.630 149.978 264.524 1.00 35.40  ? 469 LYS A CG  1 
ATOM 2370 C CD  . LYS A 1 299 ? 157.938 150.000 265.300 1.00 35.07  ? 469 LYS A CD  1 
ATOM 2371 C CE  . LYS A 1 299 ? 159.065 150.592 264.468 1.00 37.35  ? 469 LYS A CE  1 
ATOM 2372 N NZ  . LYS A 1 299 ? 160.348 150.642 265.224 1.00 38.02  ? 469 LYS A NZ  1 
ATOM 2373 N N   . PRO A 1 300 ? 153.189 147.176 265.172 1.00 33.53  ? 470 PRO A N   1 
ATOM 2374 C CA  . PRO A 1 300 ? 152.289 146.245 265.861 1.00 32.60  ? 470 PRO A CA  1 
ATOM 2375 C C   . PRO A 1 300 ? 152.721 146.003 267.303 1.00 32.01  ? 470 PRO A C   1 
ATOM 2376 O O   . PRO A 1 300 ? 153.848 146.336 267.674 1.00 32.08  ? 470 PRO A O   1 
ATOM 2377 C CB  . PRO A 1 300 ? 152.436 144.959 265.047 1.00 32.79  ? 470 PRO A CB  1 
ATOM 2378 C CG  . PRO A 1 300 ? 153.807 145.035 264.477 1.00 32.91  ? 470 PRO A CG  1 
ATOM 2379 C CD  . PRO A 1 300 ? 154.054 146.491 264.196 1.00 33.96  ? 470 PRO A CD  1 
ATOM 2380 N N   . PRO A 1 301 ? 151.828 145.431 268.104 1.00 31.22  ? 471 PRO A N   1 
ATOM 2381 C CA  . PRO A 1 301 ? 150.496 145.051 267.622 1.00 30.13  ? 471 PRO A CA  1 
ATOM 2382 C C   . PRO A 1 301 ? 149.626 146.272 267.341 1.00 28.82  ? 471 PRO A C   1 
ATOM 2383 O O   . PRO A 1 301 ? 149.593 147.204 268.142 1.00 28.50  ? 471 PRO A O   1 
ATOM 2384 C CB  . PRO A 1 301 ? 149.920 144.249 268.792 1.00 30.19  ? 471 PRO A CB  1 
ATOM 2385 C CG  . PRO A 1 301 ? 150.640 144.759 269.989 1.00 31.00  ? 471 PRO A CG  1 
ATOM 2386 C CD  . PRO A 1 301 ? 152.028 145.080 269.520 1.00 30.85  ? 471 PRO A CD  1 
ATOM 2387 N N   . ARG A 1 302 ? 148.927 146.257 266.210 1.00 27.38  ? 472 ARG A N   1 
ATOM 2388 C CA  . ARG A 1 302 ? 148.059 147.363 265.828 1.00 25.89  ? 472 ARG A CA  1 
ATOM 2389 C C   . ARG A 1 302 ? 146.659 146.862 265.486 1.00 25.07  ? 472 ARG A C   1 
ATOM 2390 O O   . ARG A 1 302 ? 146.482 145.705 265.105 1.00 24.91  ? 472 ARG A O   1 
ATOM 2391 C CB  . ARG A 1 302 ? 148.650 148.120 264.636 1.00 25.39  ? 472 ARG A CB  1 
ATOM 2392 C CG  . ARG A 1 302 ? 148.941 147.246 263.427 1.00 24.03  ? 472 ARG A CG  1 
ATOM 2393 C CD  . ARG A 1 302 ? 150.087 147.807 262.601 1.00 21.87  ? 472 ARG A CD  1 
ATOM 2394 N NE  . ARG A 1 302 ? 150.390 146.972 261.443 1.00 20.98  ? 472 ARG A NE  1 
ATOM 2395 C CZ  . ARG A 1 302 ? 151.439 147.147 260.647 1.00 20.91  ? 472 ARG A CZ  1 
ATOM 2396 N NH1 . ARG A 1 302 ? 152.295 148.134 260.885 1.00 20.93  ? 472 ARG A NH1 1 
ATOM 2397 N NH2 . ARG A 1 302 ? 151.637 146.339 259.615 1.00 20.23  ? 472 ARG A NH2 1 
ATOM 2398 N N   . ASP A 1 303 ? 145.667 147.735 265.626 1.00 23.93  ? 473 ASP A N   1 
ATOM 2399 C CA  . ASP A 1 303 ? 144.292 147.371 265.331 1.00 22.79  ? 473 ASP A CA  1 
ATOM 2400 C C   . ASP A 1 303 ? 144.150 147.026 263.843 1.00 21.68  ? 473 ASP A C   1 
ATOM 2401 O O   . ASP A 1 303 ? 145.023 147.343 263.044 1.00 21.41  ? 473 ASP A O   1 
ATOM 2402 C CB  . ASP A 1 303 ? 143.282 148.417 265.840 1.00 22.92  ? 473 ASP A CB  1 
ATOM 2403 C CG  . ASP A 1 303 ? 143.300 149.726 265.052 1.00 23.13  ? 473 ASP A CG  1 
ATOM 2404 O OD1 . ASP A 1 303 ? 143.638 149.766 263.853 1.00 21.66  ? 473 ASP A OD1 1 
ATOM 2405 O OD2 . ASP A 1 303 ? 142.920 150.741 265.662 1.00 26.58  ? 473 ASP A OD2 1 
ATOM 2406 N N   . ILE A 1 304 ? 143.075 146.352 263.475 1.00 20.90  ? 474 ILE A N   1 
ATOM 2407 C CA  . ILE A 1 304 ? 142.907 145.953 262.081 1.00 20.63  ? 474 ILE A CA  1 
ATOM 2408 C C   . ILE A 1 304 ? 142.832 147.079 261.026 1.00 20.00  ? 474 ILE A C   1 
ATOM 2409 O O   . ILE A 1 304 ? 143.147 146.836 259.862 1.00 20.40  ? 474 ILE A O   1 
ATOM 2410 C CB  . ILE A 1 304 ? 141.792 144.885 261.918 1.00 20.63  ? 474 ILE A CB  1 
ATOM 2411 C CG1 . ILE A 1 304 ? 142.058 144.008 260.697 1.00 20.68  ? 474 ILE A CG1 1 
ATOM 2412 C CG2 . ILE A 1 304 ? 140.419 145.520 261.883 1.00 21.59  ? 474 ILE A CG2 1 
ATOM 2413 C CD1 . ILE A 1 304 ? 143.281 143.137 260.846 1.00 21.44  ? 474 ILE A CD1 1 
ATOM 2414 N N   . THR A 1 305 ? 142.452 148.296 261.412 1.00 19.64  ? 475 THR A N   1 
ATOM 2415 C CA  . THR A 1 305 ? 142.398 149.407 260.432 1.00 19.66  ? 475 THR A CA  1 
ATOM 2416 C C   . THR A 1 305 ? 143.812 149.838 260.059 1.00 19.09  ? 475 THR A C   1 
ATOM 2417 O O   . THR A 1 305 ? 144.091 150.122 258.882 1.00 18.99  ? 475 THR A O   1 
ATOM 2418 C CB  . THR A 1 305 ? 141.630 150.615 260.938 1.00 19.70  ? 475 THR A CB  1 
ATOM 2419 O OG1 . THR A 1 305 ? 142.200 151.034 262.183 1.00 22.27  ? 475 THR A OG1 1 
ATOM 2420 C CG2 . THR A 1 305 ? 140.176 150.258 261.173 1.00 20.36  ? 475 THR A CG2 1 
ATOM 2421 N N   . ALA A 1 306 ? 144.704 149.851 261.061 1.00 18.45  ? 476 ALA A N   1 
ATOM 2422 C CA  . ALA A 1 306 ? 146.106 150.201 260.860 1.00 18.11  ? 476 ALA A CA  1 
ATOM 2423 C C   . ALA A 1 306 ? 146.754 149.176 259.911 1.00 18.24  ? 476 ALA A C   1 
ATOM 2424 O O   . ALA A 1 306 ? 147.458 149.540 258.960 1.00 18.04  ? 476 ALA A O   1 
ATOM 2425 C CB  . ALA A 1 306 ? 146.824 150.251 262.169 1.00 17.54  ? 476 ALA A CB  1 
ATOM 2426 N N   . GLU A 1 307 ? 146.471 147.897 260.161 1.00 18.50  ? 477 GLU A N   1 
ATOM 2427 C CA  . GLU A 1 307 ? 146.964 146.800 259.337 1.00 18.65  ? 477 GLU A CA  1 
ATOM 2428 C C   . GLU A 1 307 ? 146.353 146.943 257.971 1.00 18.39  ? 477 GLU A C   1 
ATOM 2429 O O   . GLU A 1 307 ? 147.043 146.810 256.964 1.00 18.65  ? 477 GLU A O   1 
ATOM 2430 C CB  . GLU A 1 307 ? 146.563 145.455 259.939 1.00 19.19  ? 477 GLU A CB  1 
ATOM 2431 C CG  . GLU A 1 307 ? 147.074 144.235 259.185 1.00 20.59  ? 477 GLU A CG  1 
ATOM 2432 C CD  . GLU A 1 307 ? 148.506 143.858 259.547 1.00 23.43  ? 477 GLU A CD  1 
ATOM 2433 O OE1 . GLU A 1 307 ? 148.900 143.973 260.734 1.00 24.52  ? 477 GLU A OE1 1 
ATOM 2434 O OE2 . GLU A 1 307 ? 149.238 143.423 258.633 1.00 25.10  ? 477 GLU A OE2 1 
ATOM 2435 N N   . PHE A 1 308 ? 145.059 147.245 257.922 1.00 18.37  ? 478 PHE A N   1 
ATOM 2436 C CA  . PHE A 1 308 ? 144.407 147.417 256.622 1.00 18.60  ? 478 PHE A CA  1 
ATOM 2437 C C   . PHE A 1 308 ? 145.082 148.517 255.826 1.00 18.48  ? 478 PHE A C   1 
ATOM 2438 O O   . PHE A 1 308 ? 145.301 148.366 254.632 1.00 18.12  ? 478 PHE A O   1 
ATOM 2439 C CB  . PHE A 1 308 ? 142.906 147.709 256.750 1.00 18.89  ? 478 PHE A CB  1 
ATOM 2440 C CG  . PHE A 1 308 ? 142.244 148.001 255.435 1.00 18.34  ? 478 PHE A CG  1 
ATOM 2441 C CD1 . PHE A 1 308 ? 142.090 146.999 254.485 1.00 18.53  ? 478 PHE A CD1 1 
ATOM 2442 C CD2 . PHE A 1 308 ? 141.793 149.278 255.136 1.00 19.33  ? 478 PHE A CD2 1 
ATOM 2443 C CE1 . PHE A 1 308 ? 141.495 147.265 253.238 1.00 19.95  ? 478 PHE A CE1 1 
ATOM 2444 C CE2 . PHE A 1 308 ? 141.195 149.562 253.889 1.00 20.57  ? 478 PHE A CE2 1 
ATOM 2445 C CZ  . PHE A 1 308 ? 141.048 148.551 252.937 1.00 19.61  ? 478 PHE A CZ  1 
ATOM 2446 N N   . LEU A 1 309 ? 145.412 149.620 256.501 1.00 18.78  ? 479 LEU A N   1 
ATOM 2447 C CA  . LEU A 1 309 ? 146.066 150.755 255.847 1.00 18.95  ? 479 LEU A CA  1 
ATOM 2448 C C   . LEU A 1 309 ? 147.367 150.347 255.168 1.00 19.30  ? 479 LEU A C   1 
ATOM 2449 O O   . LEU A 1 309 ? 147.578 150.656 254.013 1.00 19.41  ? 479 LEU A O   1 
ATOM 2450 C CB  . LEU A 1 309 ? 146.290 151.902 256.837 1.00 19.13  ? 479 LEU A CB  1 
ATOM 2451 C CG  . LEU A 1 309 ? 146.650 153.278 256.258 1.00 18.58  ? 479 LEU A CG  1 
ATOM 2452 C CD1 . LEU A 1 309 ? 145.662 153.722 255.174 1.00 15.59  ? 479 LEU A CD1 1 
ATOM 2453 C CD2 . LEU A 1 309 ? 146.741 154.322 257.379 1.00 17.95  ? 479 LEU A CD2 1 
ATOM 2454 N N   . VAL A 1 310 ? 148.221 149.623 255.882 1.00 20.08  ? 480 VAL A N   1 
ATOM 2455 C CA  . VAL A 1 310 ? 149.493 149.156 255.335 1.00 20.67  ? 480 VAL A CA  1 
ATOM 2456 C C   . VAL A 1 310 ? 149.267 148.261 254.125 1.00 21.24  ? 480 VAL A C   1 
ATOM 2457 O O   . VAL A 1 310 ? 149.816 148.517 253.062 1.00 21.34  ? 480 VAL A O   1 
ATOM 2458 C CB  . VAL A 1 310 ? 150.332 148.399 256.401 1.00 20.71  ? 480 VAL A CB  1 
ATOM 2459 C CG1 . VAL A 1 310 ? 151.491 147.635 255.764 1.00 20.53  ? 480 VAL A CG1 1 
ATOM 2460 C CG2 . VAL A 1 310 ? 150.840 149.359 257.454 1.00 20.31  ? 480 VAL A CG2 1 
ATOM 2461 N N   . LYS A 1 311 ? 148.460 147.217 254.298 1.00 22.28  ? 481 LYS A N   1 
ATOM 2462 C CA  . LYS A 1 311 ? 148.151 146.263 253.228 1.00 23.05  ? 481 LYS A CA  1 
ATOM 2463 C C   . LYS A 1 311 ? 147.479 146.949 252.044 1.00 23.76  ? 481 LYS A C   1 
ATOM 2464 O O   . LYS A 1 311 ? 147.815 146.689 250.884 1.00 24.07  ? 481 LYS A O   1 
ATOM 2465 C CB  . LYS A 1 311 ? 147.246 145.146 253.760 1.00 23.12  ? 481 LYS A CB  1 
ATOM 2466 C CG  . LYS A 1 311 ? 147.847 144.254 254.844 1.00 23.25  ? 481 LYS A CG  1 
ATOM 2467 C CD  . LYS A 1 311 ? 148.461 142.990 254.250 1.00 24.81  ? 481 LYS A CD  1 
ATOM 2468 C CE  . LYS A 1 311 ? 149.115 142.120 255.316 1.00 25.60  ? 481 LYS A CE  1 
ATOM 2469 N NZ  . LYS A 1 311 ? 148.120 141.515 256.231 1.00 26.33  ? 481 LYS A NZ  1 
ATOM 2470 N N   . SER A 1 312 ? 146.533 147.833 252.344 1.00 24.72  ? 482 SER A N   1 
ATOM 2471 C CA  . SER A 1 312 ? 145.794 148.572 251.319 1.00 25.72  ? 482 SER A CA  1 
ATOM 2472 C C   . SER A 1 312 ? 146.688 149.473 250.488 1.00 26.05  ? 482 SER A C   1 
ATOM 2473 O O   . SER A 1 312 ? 146.602 149.474 249.262 1.00 26.19  ? 482 SER A O   1 
ATOM 2474 C CB  . SER A 1 312 ? 144.698 149.409 251.971 1.00 25.91  ? 482 SER A CB  1 
ATOM 2475 O OG  . SER A 1 312 ? 144.341 150.487 251.131 1.00 28.20  ? 482 SER A OG  1 
ATOM 2476 N N   . LYS A 1 313 ? 147.531 150.260 251.157 1.00 26.60  ? 483 LYS A N   1 
ATOM 2477 C CA  . LYS A 1 313 ? 148.438 151.161 250.454 1.00 27.15  ? 483 LYS A CA  1 
ATOM 2478 C C   . LYS A 1 313 ? 149.416 150.343 249.619 1.00 27.34  ? 483 LYS A C   1 
ATOM 2479 O O   . LYS A 1 313 ? 149.759 150.731 248.512 1.00 27.28  ? 483 LYS A O   1 
ATOM 2480 C CB  . LYS A 1 313 ? 149.187 152.080 251.426 1.00 27.26  ? 483 LYS A CB  1 
ATOM 2481 C CG  . LYS A 1 313 ? 148.322 153.104 252.162 1.00 27.77  ? 483 LYS A CG  1 
ATOM 2482 C CD  . LYS A 1 313 ? 147.812 154.194 251.223 1.00 29.79  ? 483 LYS A CD  1 
ATOM 2483 C CE  . LYS A 1 313 ? 146.759 155.068 251.907 1.00 30.74  ? 483 LYS A CE  1 
ATOM 2484 N NZ  . LYS A 1 313 ? 146.052 155.979 250.952 1.00 30.10  ? 483 LYS A NZ  1 
ATOM 2485 N N   . HIS A 1 314 ? 149.842 149.198 250.149 1.00 27.82  ? 484 HIS A N   1 
ATOM 2486 C CA  . HIS A 1 314 ? 150.771 148.318 249.453 1.00 28.47  ? 484 HIS A CA  1 
ATOM 2487 C C   . HIS A 1 314 ? 150.172 147.908 248.122 1.00 29.04  ? 484 HIS A C   1 
ATOM 2488 O O   . HIS A 1 314 ? 150.805 148.059 247.082 1.00 29.16  ? 484 HIS A O   1 
ATOM 2489 C CB  . HIS A 1 314 ? 151.067 147.074 250.289 1.00 28.51  ? 484 HIS A CB  1 
ATOM 2490 C CG  . HIS A 1 314 ? 152.245 146.279 249.815 1.00 28.73  ? 484 HIS A CG  1 
ATOM 2491 N ND1 . HIS A 1 314 ? 152.517 146.062 248.480 1.00 29.76  ? 484 HIS A ND1 1 
ATOM 2492 C CD2 . HIS A 1 314 ? 153.210 145.624 250.505 1.00 29.03  ? 484 HIS A CD2 1 
ATOM 2493 C CE1 . HIS A 1 314 ? 153.608 145.324 248.366 1.00 29.65  ? 484 HIS A CE1 1 
ATOM 2494 N NE2 . HIS A 1 314 ? 154.044 145.040 249.581 1.00 29.61  ? 484 HIS A NE2 1 
ATOM 2495 N N   . ARG A 1 315 ? 148.944 147.402 248.159 1.00 29.76  ? 485 ARG A N   1 
ATOM 2496 C CA  . ARG A 1 315 ? 148.263 146.970 246.943 1.00 30.41  ? 485 ARG A CA  1 
ATOM 2497 C C   . ARG A 1 315 ? 148.105 148.094 245.915 1.00 30.55  ? 485 ARG A C   1 
ATOM 2498 O O   . ARG A 1 315 ? 148.348 147.885 244.722 1.00 30.77  ? 485 ARG A O   1 
ATOM 2499 C CB  . ARG A 1 315 ? 146.903 146.371 247.269 1.00 30.57  ? 485 ARG A CB  1 
ATOM 2500 C CG  . ARG A 1 315 ? 146.296 145.642 246.095 1.00 32.28  ? 485 ARG A CG  1 
ATOM 2501 C CD  . ARG A 1 315 ? 144.864 146.072 245.861 1.00 34.65  ? 485 ARG A CD  1 
ATOM 2502 N NE  . ARG A 1 315 ? 144.750 147.304 245.082 1.00 35.11  ? 485 ARG A NE  1 
ATOM 2503 C CZ  . ARG A 1 315 ? 144.518 147.349 243.772 1.00 35.88  ? 485 ARG A CZ  1 
ATOM 2504 N NH1 . ARG A 1 315 ? 144.387 146.227 243.068 1.00 35.77  ? 485 ARG A NH1 1 
ATOM 2505 N NH2 . ARG A 1 315 ? 144.422 148.525 243.164 1.00 35.85  ? 485 ARG A NH2 1 
ATOM 2506 N N   . ASP A 1 316 ? 147.697 149.272 246.379 1.00 30.85  ? 486 ASP A N   1 
ATOM 2507 C CA  . ASP A 1 316 ? 147.518 150.428 245.505 1.00 31.19  ? 486 ASP A CA  1 
ATOM 2508 C C   . ASP A 1 316 ? 148.836 150.844 244.867 1.00 31.54  ? 486 ASP A C   1 
ATOM 2509 O O   . ASP A 1 316 ? 148.873 151.248 243.698 1.00 31.70  ? 486 ASP A O   1 
ATOM 2510 C CB  . ASP A 1 316 ? 146.895 151.596 246.267 1.00 31.07  ? 486 ASP A CB  1 
ATOM 2511 C CG  . ASP A 1 316 ? 145.487 151.292 246.743 1.00 32.06  ? 486 ASP A CG  1 
ATOM 2512 O OD1 . ASP A 1 316 ? 144.952 150.222 246.371 1.00 32.73  ? 486 ASP A OD1 1 
ATOM 2513 O OD2 . ASP A 1 316 ? 144.914 152.114 247.491 1.00 33.82  ? 486 ASP A OD2 1 
ATOM 2514 N N   . LEU A 1 317 ? 149.919 150.719 245.629 1.00 31.98  ? 487 LEU A N   1 
ATOM 2515 C CA  . LEU A 1 317 ? 151.246 151.058 245.139 1.00 32.55  ? 487 LEU A CA  1 
ATOM 2516 C C   . LEU A 1 317 ? 151.703 150.072 244.057 1.00 32.91  ? 487 LEU A C   1 
ATOM 2517 O O   . LEU A 1 317 ? 152.204 150.492 243.017 1.00 32.87  ? 487 LEU A O   1 
ATOM 2518 C CB  . LEU A 1 317 ? 152.249 151.126 246.288 1.00 32.48  ? 487 LEU A CB  1 
ATOM 2519 C CG  . LEU A 1 317 ? 153.655 151.668 246.020 1.00 32.35  ? 487 LEU A CG  1 
ATOM 2520 C CD1 . LEU A 1 317 ? 153.600 152.978 245.277 1.00 32.47  ? 487 LEU A CD1 1 
ATOM 2521 C CD2 . LEU A 1 317 ? 154.376 151.857 247.347 1.00 32.74  ? 487 LEU A CD2 1 
ATOM 2522 N N   . THR A 1 318 ? 151.507 148.774 244.292 1.00 33.37  ? 488 THR A N   1 
ATOM 2523 C CA  . THR A 1 318 ? 151.882 147.748 243.320 1.00 34.01  ? 488 THR A CA  1 
ATOM 2524 C C   . THR A 1 318 ? 151.091 147.934 242.029 1.00 34.44  ? 488 THR A C   1 
ATOM 2525 O O   . THR A 1 318 ? 151.664 147.903 240.936 1.00 34.54  ? 488 THR A O   1 
ATOM 2526 C CB  . THR A 1 318 ? 151.635 146.335 243.853 1.00 33.83  ? 488 THR A CB  1 
ATOM 2527 O OG1 . THR A 1 318 ? 152.330 146.173 245.090 1.00 34.84  ? 488 THR A OG1 1 
ATOM 2528 C CG2 . THR A 1 318 ? 152.142 145.297 242.877 1.00 33.79  ? 488 THR A CG2 1 
ATOM 2529 N N   . ALA A 1 319 ? 149.781 148.146 242.160 1.00 34.93  ? 489 ALA A N   1 
ATOM 2530 C CA  . ALA A 1 319 ? 148.910 148.349 241.004 1.00 35.34  ? 489 ALA A CA  1 
ATOM 2531 C C   . ALA A 1 319 ? 149.412 149.501 240.140 1.00 35.72  ? 489 ALA A C   1 
ATOM 2532 O O   . ALA A 1 319 ? 149.486 149.368 238.915 1.00 36.18  ? 489 ALA A O   1 
ATOM 2533 C CB  . ALA A 1 319 ? 147.475 148.588 241.440 1.00 35.21  ? 489 ALA A CB  1 
ATOM 2534 N N   . LEU A 1 320 ? 149.771 150.614 240.781 1.00 36.16  ? 490 LEU A N   1 
ATOM 2535 C CA  . LEU A 1 320 ? 150.281 151.790 240.075 1.00 36.55  ? 490 LEU A CA  1 
ATOM 2536 C C   . LEU A 1 320 ? 151.649 151.533 239.458 1.00 37.07  ? 490 LEU A C   1 
ATOM 2537 O O   . LEU A 1 320 ? 151.932 152.023 238.364 1.00 37.70  ? 490 LEU A O   1 
ATOM 2538 C CB  . LEU A 1 320 ? 150.311 153.027 240.971 1.00 36.50  ? 490 LEU A CB  1 
ATOM 2539 C CG  . LEU A 1 320 ? 148.991 153.717 241.346 1.00 36.62  ? 490 LEU A CG  1 
ATOM 2540 C CD1 . LEU A 1 320 ? 149.283 155.099 241.899 1.00 36.53  ? 490 LEU A CD1 1 
ATOM 2541 C CD2 . LEU A 1 320 ? 148.019 153.829 240.170 1.00 36.47  ? 490 LEU A CD2 1 
ATOM 2542 N N   . CYS A 1 321 ? 152.483 150.745 240.126 1.00 37.43  ? 491 CYS A N   1 
ATOM 2543 C CA  . CYS A 1 321 ? 153.799 150.421 239.587 1.00 37.99  ? 491 CYS A CA  1 
ATOM 2544 C C   . CYS A 1 321 ? 153.644 149.556 238.339 1.00 38.77  ? 491 CYS A C   1 
ATOM 2545 O O   . CYS A 1 321 ? 154.466 149.625 237.423 1.00 38.72  ? 491 CYS A O   1 
ATOM 2546 C CB  . CYS A 1 321 ? 154.661 149.723 240.627 1.00 37.98  ? 491 CYS A CB  1 
ATOM 2547 S SG  . CYS A 1 321 ? 155.271 150.853 241.887 1.00 37.40  ? 491 CYS A SG  1 
ATOM 2548 N N   . LYS A 1 322 ? 152.578 148.759 238.300 1.00 39.64  ? 492 LYS A N   1 
ATOM 2549 C CA  . LYS A 1 322 ? 152.298 147.916 237.145 1.00 40.63  ? 492 LYS A CA  1 
ATOM 2550 C C   . LYS A 1 322 ? 151.861 148.802 235.989 1.00 40.93  ? 492 LYS A C   1 
ATOM 2551 O O   . LYS A 1 322 ? 152.204 148.528 234.842 1.00 41.03  ? 492 LYS A O   1 
ATOM 2552 C CB  . LYS A 1 322 ? 151.236 146.861 237.451 1.00 40.71  ? 492 LYS A CB  1 
ATOM 2553 C CG  . LYS A 1 322 ? 151.803 145.464 237.620 1.00 41.72  ? 492 LYS A CG  1 
ATOM 2554 C CD  . LYS A 1 322 ? 151.199 144.780 238.840 1.00 43.43  ? 492 LYS A CD  1 
ATOM 2555 C CE  . LYS A 1 322 ? 151.893 143.466 239.165 1.00 43.62  ? 492 LYS A CE  1 
ATOM 2556 N NZ  . LYS A 1 322 ? 151.376 142.937 240.457 1.00 44.72  ? 492 LYS A NZ  1 
ATOM 2557 N N   . GLU A 1 323 ? 151.122 149.871 236.298 1.00 41.36  ? 493 GLU A N   1 
ATOM 2558 C CA  . GLU A 1 323 ? 150.665 150.810 235.269 1.00 41.88  ? 493 GLU A CA  1 
ATOM 2559 C C   . GLU A 1 323 ? 151.854 151.533 234.653 1.00 41.92  ? 493 GLU A C   1 
ATOM 2560 O O   . GLU A 1 323 ? 151.882 151.777 233.449 1.00 42.16  ? 493 GLU A O   1 
ATOM 2561 C CB  . GLU A 1 323 ? 149.712 151.850 235.849 1.00 41.98  ? 493 GLU A CB  1 
ATOM 2562 C CG  . GLU A 1 323 ? 148.240 151.515 235.744 1.00 42.92  ? 493 GLU A CG  1 
ATOM 2563 C CD  . GLU A 1 323 ? 147.364 152.761 235.798 1.00 43.60  ? 493 GLU A CD  1 
ATOM 2564 O OE1 . GLU A 1 323 ? 147.308 153.492 234.783 1.00 43.18  ? 493 GLU A OE1 1 
ATOM 2565 O OE2 . GLU A 1 323 ? 146.731 153.001 236.854 1.00 43.45  ? 493 GLU A OE2 1 
ATOM 2566 N N   . TYR A 1 324 ? 152.825 151.877 235.496 1.00 42.03  ? 494 TYR A N   1 
ATOM 2567 C CA  . TYR A 1 324 ? 154.023 152.579 235.059 1.00 42.02  ? 494 TYR A CA  1 
ATOM 2568 C C   . TYR A 1 324 ? 154.882 151.710 234.148 1.00 42.46  ? 494 TYR A C   1 
ATOM 2569 O O   . TYR A 1 324 ? 155.401 152.195 233.149 1.00 42.58  ? 494 TYR A O   1 
ATOM 2570 C CB  . TYR A 1 324 ? 154.834 153.087 236.261 1.00 41.70  ? 494 TYR A CB  1 
ATOM 2571 C CG  . TYR A 1 324 ? 156.021 153.942 235.872 1.00 40.99  ? 494 TYR A CG  1 
ATOM 2572 C CD1 . TYR A 1 324 ? 155.897 155.324 235.737 1.00 40.06  ? 494 TYR A CD1 1 
ATOM 2573 C CD2 . TYR A 1 324 ? 157.267 153.366 235.629 1.00 40.44  ? 494 TYR A CD2 1 
ATOM 2574 C CE1 . TYR A 1 324 ? 156.987 156.107 235.369 1.00 40.35  ? 494 TYR A CE1 1 
ATOM 2575 C CE2 . TYR A 1 324 ? 158.359 154.136 235.267 1.00 40.80  ? 494 TYR A CE2 1 
ATOM 2576 C CZ  . TYR A 1 324 ? 158.215 155.504 235.131 1.00 41.09  ? 494 TYR A CZ  1 
ATOM 2577 O OH  . TYR A 1 324 ? 159.306 156.258 234.752 1.00 41.71  ? 494 TYR A OH  1 
ATOM 2578 N N   . ASP A 1 325 ? 155.020 150.430 234.487 1.00 43.10  ? 495 ASP A N   1 
ATOM 2579 C CA  . ASP A 1 325 ? 155.821 149.491 233.691 1.00 43.73  ? 495 ASP A CA  1 
ATOM 2580 C C   . ASP A 1 325 ? 155.235 149.263 232.304 1.00 44.30  ? 495 ASP A C   1 
ATOM 2581 O O   . ASP A 1 325 ? 155.970 149.017 231.344 1.00 44.14  ? 495 ASP A O   1 
ATOM 2582 C CB  . ASP A 1 325 ? 155.992 148.158 234.426 1.00 43.59  ? 495 ASP A CB  1 
ATOM 2583 C CG  . ASP A 1 325 ? 156.903 148.278 235.630 1.00 43.50  ? 495 ASP A CG  1 
ATOM 2584 O OD1 . ASP A 1 325 ? 157.684 149.254 235.663 1.00 42.70  ? 495 ASP A OD1 1 
ATOM 2585 O OD2 . ASP A 1 325 ? 156.837 147.410 236.535 1.00 43.22  ? 495 ASP A OD2 1 
ATOM 2586 N N   . GLU A 1 326 ? 153.909 149.349 232.219 1.00 45.12  ? 496 GLU A N   1 
ATOM 2587 C CA  . GLU A 1 326 ? 153.186 149.173 230.969 1.00 46.04  ? 496 GLU A CA  1 
ATOM 2588 C C   . GLU A 1 326 ? 153.404 150.391 230.088 1.00 46.24  ? 496 GLU A C   1 
ATOM 2589 O O   . GLU A 1 326 ? 153.611 150.264 228.882 1.00 46.53  ? 496 GLU A O   1 
ATOM 2590 C CB  . GLU A 1 326 ? 151.696 148.955 231.227 1.00 46.26  ? 496 GLU A CB  1 
ATOM 2591 C CG  . GLU A 1 326 ? 151.388 147.647 231.950 1.00 47.81  ? 496 GLU A CG  1 
ATOM 2592 C CD  . GLU A 1 326 ? 150.074 147.019 231.514 1.00 49.97  ? 496 GLU A CD  1 
ATOM 2593 O OE1 . GLU A 1 326 ? 149.783 147.014 230.290 1.00 51.18  ? 496 GLU A OE1 1 
ATOM 2594 O OE2 . GLU A 1 326 ? 149.341 146.513 232.393 1.00 49.90  ? 496 GLU A OE2 1 
ATOM 2595 N N   . LEU A 1 327 ? 153.378 151.570 230.702 1.00 46.48  ? 497 LEU A N   1 
ATOM 2596 C CA  . LEU A 1 327 ? 153.595 152.818 229.987 1.00 46.79  ? 497 LEU A CA  1 
ATOM 2597 C C   . LEU A 1 327 ? 155.052 152.934 229.546 1.00 47.01  ? 497 LEU A C   1 
ATOM 2598 O O   . LEU A 1 327 ? 155.335 153.493 228.490 1.00 47.16  ? 497 LEU A O   1 
ATOM 2599 C CB  . LEU A 1 327 ? 153.180 154.010 230.845 1.00 46.75  ? 497 LEU A CB  1 
ATOM 2600 C CG  . LEU A 1 327 ? 151.732 154.517 230.739 1.00 47.48  ? 497 LEU A CG  1 
ATOM 2601 C CD1 . LEU A 1 327 ? 150.686 153.397 230.570 1.00 48.14  ? 497 LEU A CD1 1 
ATOM 2602 C CD2 . LEU A 1 327 ? 151.387 155.415 231.940 1.00 46.80  ? 497 LEU A CD2 1 
ATOM 2603 N N   . ALA A 1 328 ? 155.970 152.380 230.341 1.00 47.27  ? 498 ALA A N   1 
ATOM 2604 C CA  . ALA A 1 328 ? 157.398 152.402 230.014 1.00 47.52  ? 498 ALA A CA  1 
ATOM 2605 C C   . ALA A 1 328 ? 157.651 151.496 228.814 1.00 47.76  ? 498 ALA A C   1 
ATOM 2606 O O   . ALA A 1 328 ? 158.558 151.739 228.012 1.00 47.77  ? 498 ALA A O   1 
ATOM 2607 C CB  . ALA A 1 328 ? 158.231 151.960 231.202 1.00 47.38  ? 498 ALA A CB  1 
ATOM 2608 N N   . GLU A 1 329 ? 156.827 150.456 228.705 1.00 48.08  ? 499 GLU A N   1 
ATOM 2609 C CA  . GLU A 1 329 ? 156.886 149.490 227.620 1.00 48.47  ? 499 GLU A CA  1 
ATOM 2610 C C   . GLU A 1 329 ? 156.459 150.201 226.335 1.00 48.39  ? 499 GLU A C   1 
ATOM 2611 O O   . GLU A 1 329 ? 157.078 150.020 225.285 1.00 48.41  ? 499 GLU A O   1 
ATOM 2612 C CB  . GLU A 1 329 ? 155.943 148.324 227.921 1.00 48.65  ? 499 GLU A CB  1 
ATOM 2613 C CG  . GLU A 1 329 ? 155.971 147.178 226.911 1.00 50.23  ? 499 GLU A CG  1 
ATOM 2614 C CD  . GLU A 1 329 ? 156.592 145.898 227.467 1.00 52.16  ? 499 GLU A CD  1 
ATOM 2615 O OE1 . GLU A 1 329 ? 156.602 145.710 228.708 1.00 52.16  ? 499 GLU A OE1 1 
ATOM 2616 O OE2 . GLU A 1 329 ? 157.058 145.069 226.648 1.00 53.06  ? 499 GLU A OE2 1 
ATOM 2617 N N   . THR A 1 330 ? 155.413 151.022 226.442 1.00 48.29  ? 500 THR A N   1 
ATOM 2618 C CA  . THR A 1 330 ? 154.875 151.795 225.322 1.00 48.23  ? 500 THR A CA  1 
ATOM 2619 C C   . THR A 1 330 ? 155.848 152.894 224.909 1.00 48.19  ? 500 THR A C   1 
ATOM 2620 O O   . THR A 1 330 ? 155.933 153.236 223.734 1.00 48.15  ? 500 THR A O   1 
ATOM 2621 C CB  . THR A 1 330 ? 153.502 152.413 225.675 1.00 48.31  ? 500 THR A CB  1 
ATOM 2622 O OG1 . THR A 1 330 ? 152.595 151.370 226.049 1.00 48.57  ? 500 THR A OG1 1 
ATOM 2623 C CG2 . THR A 1 330 ? 152.914 153.184 224.497 1.00 47.84  ? 500 THR A CG2 1 
ATOM 2624 N N   . GLN A 1 331 ? 156.586 153.435 225.878 1.00 48.21  ? 501 GLN A N   1 
ATOM 2625 C CA  . GLN A 1 331 ? 157.566 154.486 225.606 1.00 48.24  ? 501 GLN A CA  1 
ATOM 2626 C C   . GLN A 1 331 ? 158.684 153.968 224.703 1.00 48.55  ? 501 GLN A C   1 
ATOM 2627 O O   . GLN A 1 331 ? 159.094 154.658 223.771 1.00 48.81  ? 501 GLN A O   1 
ATOM 2628 C CB  . GLN A 1 331 ? 158.156 155.049 226.898 1.00 48.11  ? 501 GLN A CB  1 
ATOM 2629 C CG  . GLN A 1 331 ? 159.029 156.277 226.681 1.00 47.57  ? 501 GLN A CG  1 
ATOM 2630 C CD  . GLN A 1 331 ? 160.015 156.529 227.801 1.00 47.29  ? 501 GLN A CD  1 
ATOM 2631 O OE1 . GLN A 1 331 ? 159.860 156.026 228.916 1.00 48.27  ? 501 GLN A OE1 1 
ATOM 2632 N NE2 . GLN A 1 331 ? 161.039 157.318 227.512 1.00 47.09  ? 501 GLN A NE2 1 
ATOM 2633 N N   . GLY A 1 332 ? 159.160 152.753 224.981 1.00 48.75  ? 502 GLY A N   1 
ATOM 2634 C CA  . GLY A 1 332 ? 160.223 152.126 224.193 1.00 48.94  ? 502 GLY A CA  1 
ATOM 2635 C C   . GLY A 1 332 ? 159.796 151.819 222.763 1.00 49.16  ? 502 GLY A C   1 
ATOM 2636 O O   . GLY A 1 332 ? 160.630 151.786 221.856 1.00 49.04  ? 502 GLY A O   1 
ATOM 2637 N N   . LYS A 1 333 ? 158.495 151.593 222.575 1.00 49.38  ? 503 LYS A N   1 
ATOM 2638 C CA  . LYS A 1 333 ? 157.916 151.303 221.264 1.00 49.64  ? 503 LYS A CA  1 
ATOM 2639 C C   . LYS A 1 333 ? 157.841 152.568 220.425 1.00 49.72  ? 503 LYS A C   1 
ATOM 2640 O O   . LYS A 1 333 ? 158.199 152.563 219.241 1.00 50.10  ? 503 LYS A O   1 
ATOM 2641 C CB  . LYS A 1 333 ? 156.518 150.699 221.405 1.00 49.65  ? 503 LYS A CB  1 
ATOM 2642 C CG  . LYS A 1 333 ? 156.508 149.193 221.415 1.00 50.40  ? 503 LYS A CG  1 
ATOM 2643 C CD  . LYS A 1 333 ? 155.253 148.643 222.057 1.00 51.86  ? 503 LYS A CD  1 
ATOM 2644 C CE  . LYS A 1 333 ? 155.237 147.123 221.962 1.00 53.01  ? 503 LYS A CE  1 
ATOM 2645 N NZ  . LYS A 1 333 ? 154.629 146.501 223.170 1.00 54.26  ? 503 LYS A NZ  1 
ATOM 2646 N N   . LEU A 1 334 ? 157.375 153.649 221.042 1.00 49.63  ? 504 LEU A N   1 
ATOM 2647 C CA  . LEU A 1 334 ? 157.255 154.927 220.357 1.00 49.63  ? 504 LEU A CA  1 
ATOM 2648 C C   . LEU A 1 334 ? 158.626 155.518 220.062 1.00 49.72  ? 504 LEU A C   1 
ATOM 2649 O O   . LEU A 1 334 ? 158.851 156.038 218.971 1.00 49.53  ? 504 LEU A O   1 
ATOM 2650 C CB  . LEU A 1 334 ? 156.399 155.911 221.163 1.00 49.57  ? 504 LEU A CB  1 
ATOM 2651 C CG  . LEU A 1 334 ? 154.920 155.572 221.401 1.00 49.65  ? 504 LEU A CG  1 
ATOM 2652 C CD1 . LEU A 1 334 ? 154.264 156.641 222.271 1.00 49.62  ? 504 LEU A CD1 1 
ATOM 2653 C CD2 . LEU A 1 334 ? 154.130 155.379 220.102 1.00 48.94  ? 504 LEU A CD2 1 
ATOM 2654 N N   . GLU A 1 335 ? 159.539 155.416 221.027 1.00 49.95  ? 505 GLU A N   1 
ATOM 2655 C CA  . GLU A 1 335 ? 160.899 155.938 220.876 1.00 50.42  ? 505 GLU A CA  1 
ATOM 2656 C C   . GLU A 1 335 ? 161.612 155.321 219.668 1.00 50.74  ? 505 GLU A C   1 
ATOM 2657 O O   . GLU A 1 335 ? 162.256 156.032 218.891 1.00 50.76  ? 505 GLU A O   1 
ATOM 2658 C CB  . GLU A 1 335 ? 161.706 155.688 222.148 1.00 50.42  ? 505 GLU A CB  1 
ATOM 2659 C CG  . GLU A 1 335 ? 162.634 156.824 222.555 1.00 50.99  ? 505 GLU A CG  1 
ATOM 2660 C CD  . GLU A 1 335 ? 162.782 156.936 224.074 1.00 51.50  ? 505 GLU A CD  1 
ATOM 2661 O OE1 . GLU A 1 335 ? 163.108 155.921 224.729 1.00 51.22  ? 505 GLU A OE1 1 
ATOM 2662 O OE2 . GLU A 1 335 ? 162.567 158.042 224.614 1.00 51.89  ? 505 GLU A OE2 1 
ATOM 2663 N N   . GLU A 1 336 ? 161.485 154.002 219.510 1.00 51.01  ? 506 GLU A N   1 
ATOM 2664 C CA  . GLU A 1 336 ? 162.118 153.296 218.402 1.00 51.22  ? 506 GLU A CA  1 
ATOM 2665 C C   . GLU A 1 336 ? 161.378 153.546 217.089 1.00 51.12  ? 506 GLU A C   1 
ATOM 2666 O O   . GLU A 1 336 ? 161.996 153.588 216.022 1.00 51.17  ? 506 GLU A O   1 
ATOM 2667 C CB  . GLU A 1 336 ? 162.279 151.799 218.699 1.00 51.28  ? 506 GLU A CB  1 
ATOM 2668 C CG  . GLU A 1 336 ? 161.010 150.956 218.585 1.00 51.75  ? 506 GLU A CG  1 
ATOM 2669 C CD  . GLU A 1 336 ? 161.299 149.463 218.649 1.00 51.90  ? 506 GLU A CD  1 
ATOM 2670 O OE1 . GLU A 1 336 ? 161.730 148.978 219.721 1.00 51.84  ? 506 GLU A OE1 1 
ATOM 2671 O OE2 . GLU A 1 336 ? 161.096 148.774 217.623 1.00 53.17  ? 506 GLU A OE2 1 
ATOM 2672 N N   . LYS A 1 337 ? 160.064 153.741 217.176 1.00 50.98  ? 507 LYS A N   1 
ATOM 2673 C CA  . LYS A 1 337 ? 159.262 154.025 215.995 1.00 50.91  ? 507 LYS A CA  1 
ATOM 2674 C C   . LYS A 1 337 ? 159.688 155.377 215.411 1.00 50.64  ? 507 LYS A C   1 
ATOM 2675 O O   . LYS A 1 337 ? 159.473 155.640 214.240 1.00 50.73  ? 507 LYS A O   1 
ATOM 2676 C CB  . LYS A 1 337 ? 157.777 154.033 216.342 1.00 51.01  ? 507 LYS A CB  1 
ATOM 2677 C CG  . LYS A 1 337 ? 156.867 154.000 215.139 1.00 52.03  ? 507 LYS A CG  1 
ATOM 2678 C CD  . LYS A 1 337 ? 155.451 154.397 215.506 1.00 54.29  ? 507 LYS A CD  1 
ATOM 2679 C CE  . LYS A 1 337 ? 154.593 154.576 214.253 1.00 55.39  ? 507 LYS A CE  1 
ATOM 2680 N NZ  . LYS A 1 337 ? 153.298 155.244 214.579 1.00 56.21  ? 507 LYS A NZ  1 
ATOM 2681 N N   . LEU A 1 338 ? 160.307 156.216 216.241 1.00 50.60  ? 508 LEU A N   1 
ATOM 2682 C CA  . LEU A 1 338 ? 160.797 157.535 215.835 1.00 50.48  ? 508 LEU A CA  1 
ATOM 2683 C C   . LEU A 1 338 ? 162.188 157.456 215.214 1.00 50.79  ? 508 LEU A C   1 
ATOM 2684 O O   . LEU A 1 338 ? 162.472 158.157 214.242 1.00 50.80  ? 508 LEU A O   1 
ATOM 2685 C CB  . LEU A 1 338 ? 160.829 158.504 217.020 1.00 50.15  ? 508 LEU A CB  1 
ATOM 2686 C CG  . LEU A 1 338 ? 159.542 159.143 217.536 1.00 49.35  ? 508 LEU A CG  1 
ATOM 2687 C CD1 . LEU A 1 338 ? 159.838 159.828 218.850 1.00 49.22  ? 508 LEU A CD1 1 
ATOM 2688 C CD2 . LEU A 1 338 ? 158.957 160.134 216.551 1.00 48.18  ? 508 LEU A CD2 1 
ATOM 2689 N N   . GLN A 1 339 ? 163.051 156.612 215.779 1.00 51.18  ? 509 GLN A N   1 
ATOM 2690 C CA  . GLN A 1 339 ? 164.410 156.436 215.266 1.00 51.79  ? 509 GLN A CA  1 
ATOM 2691 C C   . GLN A 1 339 ? 164.330 155.744 213.903 1.00 52.00  ? 509 GLN A C   1 
ATOM 2692 O O   . GLN A 1 339 ? 165.269 155.792 213.111 1.00 51.90  ? 509 GLN A O   1 
ATOM 2693 C CB  . GLN A 1 339 ? 165.277 155.637 216.247 1.00 51.62  ? 509 GLN A CB  1 
ATOM 2694 C CG  . GLN A 1 339 ? 165.598 156.388 217.556 1.00 52.39  ? 509 GLN A CG  1 
ATOM 2695 C CD  . GLN A 1 339 ? 166.216 155.498 218.645 1.00 52.42  ? 509 GLN A CD  1 
ATOM 2696 O OE1 . GLN A 1 339 ? 167.041 154.624 218.358 1.00 53.83  ? 509 GLN A OE1 1 
ATOM 2697 N NE2 . GLN A 1 339 ? 165.825 155.728 219.899 1.00 51.92  ? 509 GLN A NE2 1 
ATOM 2698 N N   . GLU A 1 340 ? 163.178 155.126 213.653 1.00 52.32  ? 510 GLU A N   1 
ATOM 2699 C CA  . GLU A 1 340 ? 162.894 154.429 212.415 1.00 52.70  ? 510 GLU A CA  1 
ATOM 2700 C C   . GLU A 1 340 ? 162.520 155.437 211.339 1.00 52.77  ? 510 GLU A C   1 
ATOM 2701 O O   . GLU A 1 340 ? 163.060 155.399 210.231 1.00 53.01  ? 510 GLU A O   1 
ATOM 2702 C CB  . GLU A 1 340 ? 161.757 153.425 212.629 1.00 52.87  ? 510 GLU A CB  1 
ATOM 2703 C CG  . GLU A 1 340 ? 161.138 152.862 211.340 1.00 54.49  ? 510 GLU A CG  1 
ATOM 2704 C CD  . GLU A 1 340 ? 160.649 151.420 211.484 1.00 56.07  ? 510 GLU A CD  1 
ATOM 2705 O OE1 . GLU A 1 340 ? 160.644 150.886 212.621 1.00 56.07  ? 510 GLU A OE1 1 
ATOM 2706 O OE2 . GLU A 1 340 ? 160.276 150.816 210.448 1.00 56.54  ? 510 GLU A OE2 1 
ATOM 2707 N N   . LEU A 1 341 ? 161.597 156.335 211.668 1.00 52.75  ? 511 LEU A N   1 
ATOM 2708 C CA  . LEU A 1 341 ? 161.163 157.352 210.725 1.00 52.85  ? 511 LEU A CA  1 
ATOM 2709 C C   . LEU A 1 341 ? 162.282 158.358 210.469 1.00 53.17  ? 511 LEU A C   1 
ATOM 2710 O O   . LEU A 1 341 ? 162.513 158.748 209.326 1.00 53.04  ? 511 LEU A O   1 
ATOM 2711 C CB  . LEU A 1 341 ? 159.898 158.045 211.216 1.00 52.70  ? 511 LEU A CB  1 
ATOM 2712 C CG  . LEU A 1 341 ? 158.680 157.165 211.508 1.00 52.52  ? 511 LEU A CG  1 
ATOM 2713 C CD1 . LEU A 1 341 ? 157.734 157.887 212.462 1.00 52.84  ? 511 LEU A CD1 1 
ATOM 2714 C CD2 . LEU A 1 341 ? 157.942 156.744 210.248 1.00 51.82  ? 511 LEU A CD2 1 
ATOM 2715 N N   . GLU A 1 342 ? 162.988 158.752 211.530 1.00 53.68  ? 512 GLU A N   1 
ATOM 2716 C CA  . GLU A 1 342 ? 164.107 159.694 211.412 1.00 54.45  ? 512 GLU A CA  1 
ATOM 2717 C C   . GLU A 1 342 ? 165.174 159.132 210.466 1.00 54.34  ? 512 GLU A C   1 
ATOM 2718 O O   . GLU A 1 342 ? 165.812 159.882 209.726 1.00 54.55  ? 512 GLU A O   1 
ATOM 2719 C CB  . GLU A 1 342 ? 164.701 160.052 212.793 1.00 54.23  ? 512 GLU A CB  1 
ATOM 2720 C CG  . GLU A 1 342 ? 164.258 161.428 213.334 1.00 55.01  ? 512 GLU A CG  1 
ATOM 2721 C CD  . GLU A 1 342 ? 164.161 161.515 214.878 1.00 55.98  ? 512 GLU A CD  1 
ATOM 2722 O OE1 . GLU A 1 342 ? 165.029 160.962 215.599 1.00 57.85  ? 512 GLU A OE1 1 
ATOM 2723 O OE2 . GLU A 1 342 ? 163.207 162.166 215.380 1.00 57.84  ? 512 GLU A OE2 1 
ATOM 2724 N N   . ALA A 1 343 ? 165.331 157.808 210.466 1.00 54.42  ? 513 ALA A N   1 
ATOM 2725 C CA  . ALA A 1 343 ? 166.312 157.134 209.609 1.00 54.48  ? 513 ALA A CA  1 
ATOM 2726 C C   . ALA A 1 343 ? 165.831 156.845 208.180 1.00 54.53  ? 513 ALA A C   1 
ATOM 2727 O O   . ALA A 1 343 ? 166.648 156.564 207.306 1.00 54.20  ? 513 ALA A O   1 
ATOM 2728 C CB  . ALA A 1 343 ? 166.825 155.853 210.273 1.00 54.26  ? 513 ALA A CB  1 
ATOM 2729 N N   . ASN A 1 344 ? 164.519 156.915 207.948 1.00 54.93  ? 514 ASN A N   1 
ATOM 2730 C CA  . ASN A 1 344 ? 163.940 156.661 206.620 1.00 55.37  ? 514 ASN A CA  1 
ATOM 2731 C C   . ASN A 1 344 ? 163.267 157.880 205.989 1.00 55.70  ? 514 ASN A C   1 
ATOM 2732 O O   . ASN A 1 344 ? 162.055 157.856 205.759 1.00 55.38  ? 514 ASN A O   1 
ATOM 2733 C CB  . ASN A 1 344 ? 162.926 155.511 206.676 1.00 55.40  ? 514 ASN A CB  1 
ATOM 2734 C CG  . ASN A 1 344 ? 163.567 154.179 206.992 1.00 55.97  ? 514 ASN A CG  1 
ATOM 2735 O OD1 . ASN A 1 344 ? 164.346 153.645 206.203 1.00 56.29  ? 514 ASN A OD1 1 
ATOM 2736 N ND2 . ASN A 1 344 ? 163.229 153.623 208.153 1.00 56.67  ? 514 ASN A ND2 1 
ATOM 2737 N N   . PRO A 1 345 ? 164.041 158.948 205.699 1.00 56.34  ? 515 PRO A N   1 
ATOM 2738 C CA  . PRO A 1 345 ? 163.391 160.079 205.053 1.00 57.16  ? 515 PRO A CA  1 
ATOM 2739 C C   . PRO A 1 345 ? 163.142 159.793 203.581 1.00 58.24  ? 515 PRO A C   1 
ATOM 2740 O O   . PRO A 1 345 ? 163.830 158.958 202.999 1.00 58.08  ? 515 PRO A O   1 
ATOM 2741 C CB  . PRO A 1 345 ? 164.406 161.216 205.216 1.00 56.99  ? 515 PRO A CB  1 
ATOM 2742 C CG  . PRO A 1 345 ? 165.709 160.562 205.371 1.00 56.49  ? 515 PRO A CG  1 
ATOM 2743 C CD  . PRO A 1 345 ? 165.479 159.188 205.917 1.00 56.31  ? 515 PRO A CD  1 
ATOM 2744 N N   . PRO A 1 346 ? 162.166 160.471 203.017 1.00 59.47  ? 516 PRO A N   1 
ATOM 2745 C CA  . PRO A 1 346 ? 161.832 160.328 201.620 1.00 60.47  ? 516 PRO A CA  1 
ATOM 2746 C C   . PRO A 1 346 ? 162.834 161.170 200.886 1.00 61.66  ? 516 PRO A C   1 
ATOM 2747 O O   . PRO A 1 346 ? 163.707 161.716 201.532 1.00 61.36  ? 516 PRO A O   1 
ATOM 2748 C CB  . PRO A 1 346 ? 160.476 160.977 201.555 1.00 60.30  ? 516 PRO A CB  1 
ATOM 2749 C CG  . PRO A 1 346 ? 160.566 162.045 202.529 1.00 60.01  ? 516 PRO A CG  1 
ATOM 2750 C CD  . PRO A 1 346 ? 161.487 161.620 203.607 1.00 59.51  ? 516 PRO A CD  1 
ATOM 2751 N N   . SER A 1 347 ? 162.714 161.273 199.577 1.00 63.75  ? 517 SER A N   1 
ATOM 2752 C CA  . SER A 1 347 ? 163.656 162.033 198.793 1.00 65.23  ? 517 SER A CA  1 
ATOM 2753 C C   . SER A 1 347 ? 163.672 163.516 199.025 1.00 65.85  ? 517 SER A C   1 
ATOM 2754 O O   . SER A 1 347 ? 162.655 164.137 199.233 1.00 66.17  ? 517 SER A O   1 
ATOM 2755 C CB  . SER A 1 347 ? 163.522 161.703 197.318 1.00 65.53  ? 517 SER A CB  1 
ATOM 2756 O OG  . SER A 1 347 ? 162.255 162.084 196.825 1.00 67.89  ? 517 SER A OG  1 
ATOM 2757 N N   . ASP A 1 348 ? 164.870 164.062 198.961 1.00 66.77  ? 518 ASP A N   1 
ATOM 2758 C CA  . ASP A 1 348 ? 165.124 165.462 199.175 1.00 67.70  ? 518 ASP A CA  1 
ATOM 2759 C C   . ASP A 1 348 ? 164.729 166.361 198.012 1.00 68.18  ? 518 ASP A C   1 
ATOM 2760 O O   . ASP A 1 348 ? 164.175 167.421 198.212 1.00 68.04  ? 518 ASP A O   1 
ATOM 2761 C CB  . ASP A 1 348 ? 166.599 165.616 199.475 1.00 68.03  ? 518 ASP A CB  1 
ATOM 2762 C CG  . ASP A 1 348 ? 166.943 166.972 199.945 1.00 68.88  ? 518 ASP A CG  1 
ATOM 2763 O OD1 . ASP A 1 348 ? 166.022 167.787 200.079 1.00 71.39  ? 518 ASP A OD1 1 
ATOM 2764 O OD2 . ASP A 1 348 ? 168.135 167.229 200.173 1.00 69.71  ? 518 ASP A OD2 1 
ATOM 2765 N N   . VAL A 1 349 ? 165.033 165.936 196.794 1.00 68.70  ? 519 VAL A N   1 
ATOM 2766 C CA  . VAL A 1 349 ? 164.691 166.682 195.585 1.00 69.35  ? 519 VAL A CA  1 
ATOM 2767 C C   . VAL A 1 349 ? 164.195 165.747 194.505 1.00 69.40  ? 519 VAL A C   1 
ATOM 2768 O O   . VAL A 1 349 ? 164.421 164.532 194.583 1.00 69.76  ? 519 VAL A O   1 
ATOM 2769 C CB  . VAL A 1 349 ? 165.914 167.450 194.988 1.00 69.60  ? 519 VAL A CB  1 
ATOM 2770 C CG1 . VAL A 1 349 ? 166.280 168.675 195.845 1.00 70.52  ? 519 VAL A CG1 1 
ATOM 2771 C CG2 . VAL A 1 349 ? 167.124 166.510 194.791 1.00 69.68  ? 519 VAL A CG2 1 
ATOM 2772 N N   . TYR A 1 350 ? 163.533 166.314 193.496 1.00 69.30  ? 520 TYR A N   1 
ATOM 2773 C CA  . TYR A 1 350 ? 163.068 165.525 192.376 1.00 69.07  ? 520 TYR A CA  1 
ATOM 2774 C C   . TYR A 1 350 ? 164.302 165.347 191.504 1.00 69.54  ? 520 TYR A C   1 
ATOM 2775 O O   . TYR A 1 350 ? 164.679 164.221 191.185 1.00 69.88  ? 520 TYR A O   1 
ATOM 2776 C CB  . TYR A 1 350 ? 161.946 166.218 191.604 1.00 68.73  ? 520 TYR A CB  1 
ATOM 2777 C CG  . TYR A 1 350 ? 161.692 165.596 190.250 1.00 67.81  ? 520 TYR A CG  1 
ATOM 2778 C CD1 . TYR A 1 350 ? 161.501 164.216 190.114 1.00 67.37  ? 520 TYR A CD1 1 
ATOM 2779 C CD2 . TYR A 1 350 ? 161.644 166.375 189.108 1.00 67.33  ? 520 TYR A CD2 1 
ATOM 2780 C CE1 . TYR A 1 350 ? 161.272 163.634 188.865 1.00 67.53  ? 520 TYR A CE1 1 
ATOM 2781 C CE2 . TYR A 1 350 ? 161.411 165.805 187.859 1.00 67.54  ? 520 TYR A CE2 1 
ATOM 2782 C CZ  . TYR A 1 350 ? 161.231 164.438 187.748 1.00 67.35  ? 520 TYR A CZ  1 
ATOM 2783 O OH  . TYR A 1 350 ? 161.011 163.890 186.513 1.00 68.52  ? 520 TYR A OH  1 
ATOM 2784 N N   . LEU A 1 351 ? 164.947 166.461 191.160 1.00 69.87  ? 521 LEU A N   1 
ATOM 2785 C CA  . LEU A 1 351 ? 166.160 166.435 190.362 1.00 70.35  ? 521 LEU A CA  1 
ATOM 2786 C C   . LEU A 1 351 ? 167.151 167.466 190.857 1.00 70.64  ? 521 LEU A C   1 
ATOM 2787 O O   . LEU A 1 351 ? 166.806 168.636 190.993 1.00 71.03  ? 521 LEU A O   1 
ATOM 2788 C CB  . LEU A 1 351 ? 165.859 166.721 188.895 1.00 70.41  ? 521 LEU A CB  1 
ATOM 2789 C CG  . LEU A 1 351 ? 165.077 165.699 188.069 1.00 71.27  ? 521 LEU A CG  1 
ATOM 2790 C CD1 . LEU A 1 351 ? 164.771 166.307 186.722 1.00 71.34  ? 521 LEU A CD1 1 
ATOM 2791 C CD2 . LEU A 1 351 ? 165.799 164.351 187.911 1.00 71.61  ? 521 LEU A CD2 1 
ATOM 2792 N N   . SER A 1 352 ? 168.386 167.041 191.112 1.00 70.66  ? 522 SER A N   1 
ATOM 2793 C CA  . SER A 1 352 ? 169.421 167.959 191.548 1.00 70.82  ? 522 SER A CA  1 
ATOM 2794 C C   . SER A 1 352 ? 169.810 168.842 190.360 1.00 71.13  ? 522 SER A C   1 
ATOM 2795 O O   . SER A 1 352 ? 169.345 168.620 189.241 1.00 71.11  ? 522 SER A O   1 
ATOM 2796 C CB  . SER A 1 352 ? 170.642 167.187 192.043 1.00 70.82  ? 522 SER A CB  1 
ATOM 2797 O OG  . SER A 1 352 ? 171.212 166.416 191.002 1.00 70.94  ? 522 SER A OG  1 
ATOM 2798 N N   . SER A 1 353 ? 170.666 169.830 190.601 1.00 71.66  ? 523 SER A N   1 
ATOM 2799 C CA  . SER A 1 353 ? 171.143 170.733 189.557 1.00 72.27  ? 523 SER A CA  1 
ATOM 2800 C C   . SER A 1 353 ? 171.866 169.979 188.460 1.00 72.58  ? 523 SER A C   1 
ATOM 2801 O O   . SER A 1 353 ? 171.713 170.288 187.277 1.00 72.76  ? 523 SER A O   1 
ATOM 2802 C CB  . SER A 1 353 ? 172.103 171.756 190.141 1.00 72.25  ? 523 SER A CB  1 
ATOM 2803 O OG  . SER A 1 353 ? 171.377 172.857 190.622 1.00 73.60  ? 523 SER A OG  1 
ATOM 2804 N N   . ARG A 1 354 ? 172.665 168.997 188.872 1.00 72.99  ? 524 ARG A N   1 
ATOM 2805 C CA  . ARG A 1 354 ? 173.433 168.166 187.962 1.00 73.34  ? 524 ARG A CA  1 
ATOM 2806 C C   . ARG A 1 354 ? 172.475 167.330 187.126 1.00 73.19  ? 524 ARG A C   1 
ATOM 2807 O O   . ARG A 1 354 ? 172.607 167.256 185.901 1.00 73.21  ? 524 ARG A O   1 
ATOM 2808 C CB  . ARG A 1 354 ? 174.383 167.270 188.753 1.00 73.55  ? 524 ARG A CB  1 
ATOM 2809 C CG  . ARG A 1 354 ? 175.669 166.910 188.046 1.00 75.15  ? 524 ARG A CG  1 
ATOM 2810 C CD  . ARG A 1 354 ? 176.721 166.458 189.055 1.00 79.68  ? 524 ARG A CD  1 
ATOM 2811 N NE  . ARG A 1 354 ? 177.650 165.463 188.509 1.00 83.26  ? 524 ARG A NE  1 
ATOM 2812 C CZ  . ARG A 1 354 ? 177.359 164.173 188.314 1.00 85.30  ? 524 ARG A CZ  1 
ATOM 2813 N NH1 . ARG A 1 354 ? 176.153 163.692 188.600 1.00 86.38  ? 524 ARG A NH1 1 
ATOM 2814 N NH2 . ARG A 1 354 ? 178.277 163.357 187.811 1.00 86.27  ? 524 ARG A NH2 1 
ATOM 2815 N N   . ASP A 1 355 ? 171.497 166.718 187.791 1.00 73.10  ? 525 ASP A N   1 
ATOM 2816 C CA  . ASP A 1 355 ? 170.512 165.888 187.102 1.00 72.86  ? 525 ASP A CA  1 
ATOM 2817 C C   . ASP A 1 355 ? 169.759 166.708 186.071 1.00 72.32  ? 525 ASP A C   1 
ATOM 2818 O O   . ASP A 1 355 ? 169.515 166.236 184.968 1.00 72.57  ? 525 ASP A O   1 
ATOM 2819 C CB  . ASP A 1 355 ? 169.525 165.255 188.092 1.00 73.30  ? 525 ASP A CB  1 
ATOM 2820 C CG  . ASP A 1 355 ? 170.208 164.377 189.143 1.00 74.45  ? 525 ASP A CG  1 
ATOM 2821 O OD1 . ASP A 1 355 ? 171.248 163.746 188.844 1.00 75.28  ? 525 ASP A OD1 1 
ATOM 2822 O OD2 . ASP A 1 355 ? 169.690 164.318 190.282 1.00 76.51  ? 525 ASP A OD2 1 
ATOM 2823 N N   . ARG A 1 356 ? 169.406 167.940 186.428 1.00 71.74  ? 526 ARG A N   1 
ATOM 2824 C CA  . ARG A 1 356 ? 168.683 168.825 185.526 1.00 71.17  ? 526 ARG A CA  1 
ATOM 2825 C C   . ARG A 1 356 ? 169.512 169.175 184.287 1.00 70.42  ? 526 ARG A C   1 
ATOM 2826 O O   . ARG A 1 356 ? 168.969 169.267 183.194 1.00 70.39  ? 526 ARG A O   1 
ATOM 2827 C CB  . ARG A 1 356 ? 168.214 170.096 186.245 1.00 71.43  ? 526 ARG A CB  1 
ATOM 2828 C CG  . ARG A 1 356 ? 167.636 171.166 185.295 1.00 73.21  ? 526 ARG A CG  1 
ATOM 2829 C CD  . ARG A 1 356 ? 166.198 170.856 184.851 1.00 74.88  ? 526 ARG A CD  1 
ATOM 2830 N NE  . ARG A 1 356 ? 165.922 171.330 183.492 1.00 75.83  ? 526 ARG A NE  1 
ATOM 2831 C CZ  . ARG A 1 356 ? 164.713 171.656 183.032 1.00 75.36  ? 526 ARG A CZ  1 
ATOM 2832 N NH1 . ARG A 1 356 ? 163.640 171.581 183.820 1.00 74.91  ? 526 ARG A NH1 1 
ATOM 2833 N NH2 . ARG A 1 356 ? 164.582 172.076 181.781 1.00 73.87  ? 526 ARG A NH2 1 
ATOM 2834 N N   . GLN A 1 357 ? 170.816 169.360 184.455 1.00 69.61  ? 527 GLN A N   1 
ATOM 2835 C CA  . GLN A 1 357 ? 171.674 169.684 183.327 1.00 69.15  ? 527 GLN A CA  1 
ATOM 2836 C C   . GLN A 1 357 ? 171.739 168.496 182.380 1.00 68.81  ? 527 GLN A C   1 
ATOM 2837 O O   . GLN A 1 357 ? 171.623 168.665 181.156 1.00 69.23  ? 527 GLN A O   1 
ATOM 2838 C CB  . GLN A 1 357 ? 173.071 170.087 183.781 1.00 69.10  ? 527 GLN A CB  1 
ATOM 2839 C CG  . GLN A 1 357 ? 173.170 171.508 184.316 1.00 70.12  ? 527 GLN A CG  1 
ATOM 2840 C CD  . GLN A 1 357 ? 174.390 171.740 185.228 1.00 71.72  ? 527 GLN A CD  1 
ATOM 2841 O OE1 . GLN A 1 357 ? 175.024 170.796 185.724 1.00 71.91  ? 527 GLN A OE1 1 
ATOM 2842 N NE2 . GLN A 1 357 ? 174.716 173.007 185.449 1.00 71.17  ? 527 GLN A NE2 1 
ATOM 2843 N N   . ILE A 1 358 ? 171.893 167.298 182.934 1.00 68.08  ? 528 ILE A N   1 
ATOM 2844 C CA  . ILE A 1 358 ? 171.945 166.098 182.102 1.00 67.59  ? 528 ILE A CA  1 
ATOM 2845 C C   . ILE A 1 358 ? 170.601 165.916 181.407 1.00 67.43  ? 528 ILE A C   1 
ATOM 2846 O O   . ILE A 1 358 ? 170.551 165.563 180.225 1.00 67.43  ? 528 ILE A O   1 
ATOM 2847 C CB  . ILE A 1 358 ? 172.363 164.848 182.893 1.00 67.65  ? 528 ILE A CB  1 
ATOM 2848 C CG1 . ILE A 1 358 ? 173.771 165.054 183.473 1.00 67.40  ? 528 ILE A CG1 1 
ATOM 2849 C CG2 . ILE A 1 358 ? 172.333 163.607 182.000 1.00 66.94  ? 528 ILE A CG2 1 
ATOM 2850 C CD1 . ILE A 1 358 ? 174.125 164.161 184.649 1.00 66.43  ? 528 ILE A CD1 1 
ATOM 2851 N N   . LEU A 1 359 ? 169.514 166.195 182.126 1.00 67.17  ? 529 LEU A N   1 
ATOM 2852 C CA  . LEU A 1 359 ? 168.184 166.088 181.541 1.00 66.97  ? 529 LEU A CA  1 
ATOM 2853 C C   . LEU A 1 359 ? 168.046 167.077 180.392 1.00 67.13  ? 529 LEU A C   1 
ATOM 2854 O O   . LEU A 1 359 ? 167.485 166.747 179.346 1.00 67.73  ? 529 LEU A O   1 
ATOM 2855 C CB  . LEU A 1 359 ? 167.086 166.303 182.584 1.00 67.10  ? 529 LEU A CB  1 
ATOM 2856 C CG  . LEU A 1 359 ? 165.647 166.283 182.043 1.00 67.19  ? 529 LEU A CG  1 
ATOM 2857 C CD1 . LEU A 1 359 ? 165.320 164.994 181.276 1.00 66.85  ? 529 LEU A CD1 1 
ATOM 2858 C CD2 . LEU A 1 359 ? 164.629 166.554 183.140 1.00 66.19  ? 529 LEU A CD2 1 
ATOM 2859 N N   . ASP A 1 360 ? 168.584 168.278 180.570 1.00 67.13  ? 530 ASP A N   1 
ATOM 2860 C CA  . ASP A 1 360 ? 168.532 169.280 179.525 1.00 67.37  ? 530 ASP A CA  1 
ATOM 2861 C C   . ASP A 1 360 ? 169.291 168.812 178.287 1.00 67.56  ? 530 ASP A C   1 
ATOM 2862 O O   . ASP A 1 360 ? 168.972 169.233 177.168 1.00 67.70  ? 530 ASP A O   1 
ATOM 2863 C CB  . ASP A 1 360 ? 169.051 170.626 180.016 1.00 67.56  ? 530 ASP A CB  1 
ATOM 2864 C CG  . ASP A 1 360 ? 167.968 171.454 180.698 1.00 68.84  ? 530 ASP A CG  1 
ATOM 2865 O OD1 . ASP A 1 360 ? 166.777 171.300 180.360 1.00 71.52  ? 530 ASP A OD1 1 
ATOM 2866 O OD2 . ASP A 1 360 ? 168.304 172.269 181.579 1.00 70.09  ? 530 ASP A OD2 1 
ATOM 2867 N N   . TRP A 1 361 ? 170.273 167.926 178.466 1.00 67.47  ? 531 TRP A N   1 
ATOM 2868 C CA  . TRP A 1 361 ? 171.009 167.420 177.320 1.00 67.37  ? 531 TRP A CA  1 
ATOM 2869 C C   . TRP A 1 361 ? 170.035 166.603 176.488 1.00 67.48  ? 531 TRP A C   1 
ATOM 2870 O O   . TRP A 1 361 ? 169.979 166.749 175.267 1.00 67.74  ? 531 TRP A O   1 
ATOM 2871 C CB  . TRP A 1 361 ? 172.230 166.588 177.706 1.00 67.67  ? 531 TRP A CB  1 
ATOM 2872 C CG  . TRP A 1 361 ? 173.000 166.180 176.487 1.00 67.88  ? 531 TRP A CG  1 
ATOM 2873 C CD1 . TRP A 1 361 ? 174.026 166.861 175.904 1.00 68.29  ? 531 TRP A CD1 1 
ATOM 2874 C CD2 . TRP A 1 361 ? 172.775 165.024 175.676 1.00 68.08  ? 531 TRP A CD2 1 
ATOM 2875 N NE1 . TRP A 1 361 ? 174.462 166.200 174.788 1.00 68.20  ? 531 TRP A NE1 1 
ATOM 2876 C CE2 . TRP A 1 361 ? 173.710 165.070 174.618 1.00 68.20  ? 531 TRP A CE2 1 
ATOM 2877 C CE3 . TRP A 1 361 ? 171.877 163.947 175.745 1.00 68.69  ? 531 TRP A CE3 1 
ATOM 2878 C CZ2 . TRP A 1 361 ? 173.776 164.080 173.623 1.00 68.49  ? 531 TRP A CZ2 1 
ATOM 2879 C CZ3 . TRP A 1 361 ? 171.936 162.957 174.748 1.00 69.03  ? 531 TRP A CZ3 1 
ATOM 2880 C CH2 . TRP A 1 361 ? 172.881 163.037 173.700 1.00 68.50  ? 531 TRP A CH2 1 
ATOM 2881 N N   . HIS A 1 362 ? 169.236 165.769 177.151 1.00 67.24  ? 532 HIS A N   1 
ATOM 2882 C CA  . HIS A 1 362 ? 168.256 164.964 176.441 1.00 66.98  ? 532 HIS A CA  1 
ATOM 2883 C C   . HIS A 1 362 ? 167.229 165.841 175.732 1.00 67.04  ? 532 HIS A C   1 
ATOM 2884 O O   . HIS A 1 362 ? 166.842 165.531 174.601 1.00 66.78  ? 532 HIS A O   1 
ATOM 2885 C CB  . HIS A 1 362 ? 167.608 163.933 177.352 1.00 66.72  ? 532 HIS A CB  1 
ATOM 2886 C CG  . HIS A 1 362 ? 168.560 162.871 177.787 1.00 66.70  ? 532 HIS A CG  1 
ATOM 2887 N ND1 . HIS A 1 362 ? 168.956 161.845 176.956 1.00 66.77  ? 532 HIS A ND1 1 
ATOM 2888 C CD2 . HIS A 1 362 ? 169.245 162.709 178.942 1.00 65.18  ? 532 HIS A CD2 1 
ATOM 2889 C CE1 . HIS A 1 362 ? 169.829 161.082 177.590 1.00 66.12  ? 532 HIS A CE1 1 
ATOM 2890 N NE2 . HIS A 1 362 ? 170.018 161.583 178.798 1.00 65.49  ? 532 HIS A NE2 1 
ATOM 2891 N N   . PHE A 1 363 ? 166.813 166.935 176.372 1.00 66.80  ? 533 PHE A N   1 
ATOM 2892 C CA  . PHE A 1 363 ? 165.854 167.842 175.736 1.00 66.67  ? 533 PHE A CA  1 
ATOM 2893 C C   . PHE A 1 363 ? 166.505 168.495 174.516 1.00 66.66  ? 533 PHE A C   1 
ATOM 2894 O O   . PHE A 1 363 ? 165.890 168.622 173.453 1.00 66.02  ? 533 PHE A O   1 
ATOM 2895 C CB  . PHE A 1 363 ? 165.351 168.902 176.707 1.00 66.60  ? 533 PHE A CB  1 
ATOM 2896 C CG  . PHE A 1 363 ? 164.436 168.370 177.793 1.00 66.41  ? 533 PHE A CG  1 
ATOM 2897 C CD1 . PHE A 1 363 ? 163.471 167.403 177.512 1.00 64.73  ? 533 PHE A CD1 1 
ATOM 2898 C CD2 . PHE A 1 363 ? 164.516 168.882 179.095 1.00 66.46  ? 533 PHE A CD2 1 
ATOM 2899 C CE1 . PHE A 1 363 ? 162.617 166.931 178.512 1.00 64.86  ? 533 PHE A CE1 1 
ATOM 2900 C CE2 . PHE A 1 363 ? 163.659 168.418 180.107 1.00 66.40  ? 533 PHE A CE2 1 
ATOM 2901 C CZ  . PHE A 1 363 ? 162.710 167.436 179.811 1.00 65.55  ? 533 PHE A CZ  1 
ATOM 2902 N N   . ALA A 1 364 ? 167.769 168.881 174.662 1.00 67.02  ? 534 ALA A N   1 
ATOM 2903 C CA  . ALA A 1 364 ? 168.490 169.491 173.550 1.00 67.24  ? 534 ALA A CA  1 
ATOM 2904 C C   . ALA A 1 364 ? 168.509 168.497 172.385 1.00 67.45  ? 534 ALA A C   1 
ATOM 2905 O O   . ALA A 1 364 ? 168.326 168.877 171.221 1.00 67.42  ? 534 ALA A O   1 
ATOM 2906 C CB  . ALA A 1 364 ? 169.905 169.881 173.956 1.00 66.60  ? 534 ALA A CB  1 
ATOM 2907 N N   . ASN A 1 365 ? 168.698 167.224 172.718 1.00 67.77  ? 535 ASN A N   1 
ATOM 2908 C CA  . ASN A 1 365 ? 168.738 166.168 171.720 1.00 68.45  ? 535 ASN A CA  1 
ATOM 2909 C C   . ASN A 1 365 ? 167.425 166.044 170.961 1.00 68.52  ? 535 ASN A C   1 
ATOM 2910 O O   . ASN A 1 365 ? 167.424 165.867 169.740 1.00 69.32  ? 535 ASN A O   1 
ATOM 2911 C CB  . ASN A 1 365 ? 169.147 164.849 172.355 1.00 68.89  ? 535 ASN A CB  1 
ATOM 2912 C CG  . ASN A 1 365 ? 169.569 163.821 171.337 1.00 69.09  ? 535 ASN A CG  1 
ATOM 2913 O OD1 . ASN A 1 365 ? 169.280 162.650 171.507 1.00 72.11  ? 535 ASN A OD1 1 
ATOM 2914 N ND2 . ASN A 1 365 ? 170.275 164.242 170.294 1.00 67.67  ? 535 ASN A ND2 1 
ATOM 2915 N N   . LEU A 1 366 ? 166.317 166.198 171.679 1.00 68.39  ? 536 LEU A N   1 
ATOM 2916 C CA  . LEU A 1 366 ? 164.988 166.157 171.093 1.00 68.19  ? 536 LEU A CA  1 
ATOM 2917 C C   . LEU A 1 366 ? 164.779 167.423 170.256 1.00 68.78  ? 536 LEU A C   1 
ATOM 2918 O O   . LEU A 1 366 ? 164.156 167.375 169.193 1.00 69.24  ? 536 LEU A O   1 
ATOM 2919 C CB  . LEU A 1 366 ? 163.948 166.080 172.204 1.00 68.17  ? 536 LEU A CB  1 
ATOM 2920 C CG  . LEU A 1 366 ? 162.493 165.773 171.849 1.00 68.46  ? 536 LEU A CG  1 
ATOM 2921 C CD1 . LEU A 1 366 ? 162.344 164.472 171.032 1.00 65.90  ? 536 LEU A CD1 1 
ATOM 2922 C CD2 . LEU A 1 366 ? 161.699 165.708 173.150 1.00 67.27  ? 536 LEU A CD2 1 
ATOM 2923 N N   . GLU A 1 367 ? 165.320 168.547 170.727 1.00 69.25  ? 537 GLU A N   1 
ATOM 2924 C CA  . GLU A 1 367 ? 165.210 169.816 170.011 1.00 70.16  ? 537 GLU A CA  1 
ATOM 2925 C C   . GLU A 1 367 ? 165.992 169.711 168.717 1.00 70.44  ? 537 GLU A C   1 
ATOM 2926 O O   . GLU A 1 367 ? 165.600 170.279 167.690 1.00 71.18  ? 537 GLU A O   1 
ATOM 2927 C CB  . GLU A 1 367 ? 165.655 171.010 170.875 1.00 70.02  ? 537 GLU A CB  1 
ATOM 2928 C CG  . GLU A 1 367 ? 164.606 171.352 171.913 1.00 70.68  ? 537 GLU A CG  1 
ATOM 2929 C CD  . GLU A 1 367 ? 164.994 172.414 172.915 1.00 71.22  ? 537 GLU A CD  1 
ATOM 2930 O OE1 . GLU A 1 367 ? 166.200 172.572 173.239 1.00 72.84  ? 537 GLU A OE1 1 
ATOM 2931 O OE2 . GLU A 1 367 ? 164.056 173.091 173.410 1.00 72.97  ? 537 GLU A OE2 1 
ATOM 2932 N N   . PHE A 1 368 ? 167.096 168.961 168.759 1.00 70.65  ? 538 PHE A N   1 
ATOM 2933 C CA  . PHE A 1 368 ? 167.883 168.735 167.521 1.00 71.26  ? 538 PHE A CA  1 
ATOM 2934 C C   . PHE A 1 368 ? 167.051 167.887 166.555 1.00 70.99  ? 538 PHE A C   1 
ATOM 2935 O O   . PHE A 1 368 ? 166.890 168.294 165.387 1.00 71.21  ? 538 PHE A O   1 
ATOM 2936 C CB  . PHE A 1 368 ? 169.214 168.048 167.833 1.00 72.18  ? 538 PHE A CB  1 
ATOM 2937 C CG  . PHE A 1 368 ? 169.869 167.424 166.628 1.00 74.39  ? 538 PHE A CG  1 
ATOM 2938 C CD1 . PHE A 1 368 ? 170.400 168.214 165.621 1.00 74.82  ? 538 PHE A CD1 1 
ATOM 2939 C CD2 . PHE A 1 368 ? 169.939 166.047 166.491 1.00 76.74  ? 538 PHE A CD2 1 
ATOM 2940 C CE1 . PHE A 1 368 ? 170.993 167.640 164.508 1.00 75.51  ? 538 PHE A CE1 1 
ATOM 2941 C CE2 . PHE A 1 368 ? 170.534 165.475 165.378 1.00 77.70  ? 538 PHE A CE2 1 
ATOM 2942 C CZ  . PHE A 1 368 ? 171.060 166.272 164.389 1.00 76.53  ? 538 PHE A CZ  1 
ATOM 2943 N N   . ALA A 1 369 ? 166.538 166.748 167.031 1.00 70.31  ? 539 ALA A N   1 
ATOM 2944 C CA  . ALA A 1 369 ? 165.762 165.873 166.163 1.00 69.74  ? 539 ALA A CA  1 
ATOM 2945 C C   . ALA A 1 369 ? 164.603 166.612 165.468 1.00 69.74  ? 539 ALA A C   1 
ATOM 2946 O O   . ALA A 1 369 ? 164.339 166.407 164.281 1.00 69.92  ? 539 ALA A O   1 
ATOM 2947 C CB  . ALA A 1 369 ? 165.239 164.698 166.949 1.00 69.13  ? 539 ALA A CB  1 
ATOM 2948 N N   . ASN A 1 370 ? 163.904 167.465 166.207 1.00 69.15  ? 540 ASN A N   1 
ATOM 2949 C CA  . ASN A 1 370 ? 162.790 168.184 165.630 1.00 68.32  ? 540 ASN A CA  1 
ATOM 2950 C C   . ASN A 1 370 ? 163.157 169.562 165.094 1.00 68.20  ? 540 ASN A C   1 
ATOM 2951 O O   . ASN A 1 370 ? 162.292 170.306 164.649 1.00 67.77  ? 540 ASN A O   1 
ATOM 2952 C CB  . ASN A 1 370 ? 161.654 168.252 166.629 1.00 68.10  ? 540 ASN A CB  1 
ATOM 2953 C CG  . ASN A 1 370 ? 161.066 166.905 166.883 1.00 69.56  ? 540 ASN A CG  1 
ATOM 2954 O OD1 . ASN A 1 370 ? 160.324 166.386 166.054 1.00 72.17  ? 540 ASN A OD1 1 
ATOM 2955 N ND2 . ASN A 1 370 ? 161.425 166.292 168.008 1.00 69.85  ? 540 ASN A ND2 1 
ATOM 2956 N N   . ALA A 1 371 ? 164.450 169.880 165.121 1.00 68.11  ? 541 ALA A N   1 
ATOM 2957 C CA  . ALA A 1 371 ? 164.961 171.174 164.636 1.00 68.23  ? 541 ALA A CA  1 
ATOM 2958 C C   . ALA A 1 371 ? 164.166 172.368 165.156 1.00 67.77  ? 541 ALA A C   1 
ATOM 2959 O O   . ALA A 1 371 ? 163.913 173.320 164.417 1.00 67.03  ? 541 ALA A O   1 
ATOM 2960 C CB  . ALA A 1 371 ? 165.022 171.202 163.110 1.00 68.39  ? 541 ALA A CB  1 
ATOM 2961 N N   . THR A 1 372 ? 163.767 172.311 166.425 1.00 67.23  ? 542 THR A N   1 
ATOM 2962 C CA  . THR A 1 372 ? 162.997 173.400 166.992 1.00 67.21  ? 542 THR A CA  1 
ATOM 2963 C C   . THR A 1 372 ? 162.938 173.323 168.514 1.00 66.87  ? 542 THR A C   1 
ATOM 2964 O O   . THR A 1 372 ? 163.035 172.236 169.073 1.00 67.85  ? 542 THR A O   1 
ATOM 2965 C CB  . THR A 1 372 ? 161.592 173.418 166.397 1.00 67.00  ? 542 THR A CB  1 
ATOM 2966 O OG1 . THR A 1 372 ? 161.036 174.722 166.556 1.00 69.09  ? 542 THR A OG1 1 
ATOM 2967 C CG2 . THR A 1 372 ? 160.698 172.391 167.055 1.00 66.36  ? 542 THR A CG2 1 
ATOM 2968 N N   . PRO A 1 373 ? 162.840 174.475 169.197 1.00 66.48  ? 543 PRO A N   1 
ATOM 2969 C CA  . PRO A 1 373 ? 162.683 174.406 170.662 1.00 65.92  ? 543 PRO A CA  1 
ATOM 2970 C C   . PRO A 1 373 ? 161.417 173.650 171.062 1.00 66.04  ? 543 PRO A C   1 
ATOM 2971 O O   . PRO A 1 373 ? 160.397 173.755 170.382 1.00 66.59  ? 543 PRO A O   1 
ATOM 2972 C CB  . PRO A 1 373 ? 162.576 175.877 171.070 1.00 65.45  ? 543 PRO A CB  1 
ATOM 2973 C CG  . PRO A 1 373 ? 163.331 176.615 170.000 1.00 66.27  ? 543 PRO A CG  1 
ATOM 2974 C CD  . PRO A 1 373 ? 162.941 175.869 168.721 1.00 66.12  ? 543 PRO A CD  1 
ATOM 2975 N N   . LEU A 1 374 ? 161.474 172.889 172.149 1.00 65.86  ? 544 LEU A N   1 
ATOM 2976 C CA  . LEU A 1 374 ? 160.313 172.138 172.605 1.00 65.81  ? 544 LEU A CA  1 
ATOM 2977 C C   . LEU A 1 374 ? 159.071 173.006 172.866 1.00 66.11  ? 544 LEU A C   1 
ATOM 2978 O O   . LEU A 1 374 ? 157.938 172.514 172.861 1.00 66.41  ? 544 LEU A O   1 
ATOM 2979 C CB  . LEU A 1 374 ? 160.656 171.322 173.852 1.00 65.16  ? 544 LEU A CB  1 
ATOM 2980 C CG  . LEU A 1 374 ? 161.732 170.256 173.654 1.00 65.72  ? 544 LEU A CG  1 
ATOM 2981 C CD1 . LEU A 1 374 ? 161.799 169.373 174.877 1.00 64.59  ? 544 LEU A CD1 1 
ATOM 2982 C CD2 . LEU A 1 374 ? 161.500 169.396 172.379 1.00 64.43  ? 544 LEU A CD2 1 
ATOM 2983 N N   . SER A 1 375 ? 159.277 174.292 173.103 1.00 66.31  ? 545 SER A N   1 
ATOM 2984 C CA  . SER A 1 375 ? 158.161 175.189 173.379 1.00 66.71  ? 545 SER A CA  1 
ATOM 2985 C C   . SER A 1 375 ? 157.332 175.523 172.139 1.00 67.00  ? 545 SER A C   1 
ATOM 2986 O O   . SER A 1 375 ? 156.306 176.202 172.262 1.00 66.98  ? 545 SER A O   1 
ATOM 2987 C CB  . SER A 1 375 ? 158.668 176.475 174.013 1.00 66.63  ? 545 SER A CB  1 
ATOM 2988 O OG  . SER A 1 375 ? 159.562 177.131 173.128 1.00 67.78  ? 545 SER A OG  1 
ATOM 2989 N N   . THR A 1 376 ? 157.775 175.066 170.960 1.00 66.96  ? 546 THR A N   1 
ATOM 2990 C CA  . THR A 1 376 ? 157.052 175.337 169.711 1.00 67.59  ? 546 THR A CA  1 
ATOM 2991 C C   . THR A 1 376 ? 156.322 174.112 169.138 1.00 68.21  ? 546 THR A C   1 
ATOM 2992 O O   . THR A 1 376 ? 155.492 174.248 168.227 1.00 68.69  ? 546 THR A O   1 
ATOM 2993 C CB  . THR A 1 376 ? 157.975 175.907 168.589 1.00 67.77  ? 546 THR A CB  1 
ATOM 2994 O OG1 . THR A 1 376 ? 158.949 174.925 168.186 1.00 68.59  ? 546 THR A OG1 1 
ATOM 2995 C CG2 . THR A 1 376 ? 158.669 177.162 169.033 1.00 66.38  ? 546 THR A CG2 1 
ATOM 2996 N N   . LEU A 1 377 ? 156.636 172.925 169.654 1.00 68.34  ? 547 LEU A N   1 
ATOM 2997 C CA  . LEU A 1 377 ? 156.022 171.682 169.183 1.00 68.57  ? 547 LEU A CA  1 
ATOM 2998 C C   . LEU A 1 377 ? 154.627 171.448 169.724 1.00 69.09  ? 547 LEU A C   1 
ATOM 2999 O O   . LEU A 1 377 ? 154.363 171.687 170.908 1.00 69.86  ? 547 LEU A O   1 
ATOM 3000 C CB  . LEU A 1 377 ? 156.876 170.486 169.578 1.00 67.98  ? 547 LEU A CB  1 
ATOM 3001 C CG  . LEU A 1 377 ? 158.178 170.284 168.832 1.00 68.16  ? 547 LEU A CG  1 
ATOM 3002 C CD1 . LEU A 1 377 ? 158.955 169.186 169.536 1.00 67.30  ? 547 LEU A CD1 1 
ATOM 3003 C CD2 . LEU A 1 377 ? 157.937 169.945 167.344 1.00 66.98  ? 547 LEU A CD2 1 
ATOM 3004 N N   . SER A 1 378 ? 153.750 170.939 168.871 1.00 69.02  ? 548 SER A N   1 
ATOM 3005 C CA  . SER A 1 378 ? 152.391 170.633 169.255 1.00 69.17  ? 548 SER A CA  1 
ATOM 3006 C C   . SER A 1 378 ? 152.374 169.496 170.273 1.00 69.87  ? 548 SER A C   1 
ATOM 3007 O O   . SER A 1 378 ? 152.933 168.433 170.007 1.00 70.69  ? 548 SER A O   1 
ATOM 3008 C CB  . SER A 1 378 ? 151.628 170.208 168.017 1.00 68.72  ? 548 SER A CB  1 
ATOM 3009 O OG  . SER A 1 378 ? 150.519 169.412 168.353 1.00 68.68  ? 548 SER A OG  1 
ATOM 3010 N N   . LEU A 1 379 ? 151.741 169.673 171.430 1.00 69.93  ? 549 LEU A N   1 
ATOM 3011 C CA  . LEU A 1 379 ? 151.732 168.556 172.376 1.00 70.51  ? 549 LEU A CA  1 
ATOM 3012 C C   . LEU A 1 379 ? 150.931 167.397 171.803 1.00 71.87  ? 549 LEU A C   1 
ATOM 3013 O O   . LEU A 1 379 ? 151.296 166.230 171.976 1.00 72.01  ? 549 LEU A O   1 
ATOM 3014 C CB  . LEU A 1 379 ? 151.163 168.940 173.752 1.00 70.20  ? 549 LEU A CB  1 
ATOM 3015 C CG  . LEU A 1 379 ? 150.720 167.783 174.670 1.00 69.57  ? 549 LEU A CG  1 
ATOM 3016 C CD1 . LEU A 1 379 ? 151.891 166.920 175.159 1.00 69.83  ? 549 LEU A CD1 1 
ATOM 3017 C CD2 . LEU A 1 379 ? 149.933 168.290 175.856 1.00 69.52  ? 549 LEU A CD2 1 
ATOM 3018 N N   . LYS A 1 380 ? 149.841 167.729 171.122 1.00 72.98  ? 550 LYS A N   1 
ATOM 3019 C CA  . LYS A 1 380 ? 148.970 166.723 170.569 1.00 74.89  ? 550 LYS A CA  1 
ATOM 3020 C C   . LYS A 1 380 ? 149.512 165.947 169.384 1.00 74.56  ? 550 LYS A C   1 
ATOM 3021 O O   . LYS A 1 380 ? 149.244 164.759 169.263 1.00 74.66  ? 550 LYS A O   1 
ATOM 3022 C CB  . LYS A 1 380 ? 147.615 167.335 170.207 1.00 74.88  ? 550 LYS A CB  1 
ATOM 3023 C CG  . LYS A 1 380 ? 146.496 166.296 170.118 1.00 77.72  ? 550 LYS A CG  1 
ATOM 3024 C CD  . LYS A 1 380 ? 145.172 166.872 169.594 1.00 78.50  ? 550 LYS A CD  1 
ATOM 3025 C CE  . LYS A 1 380 ? 144.366 167.543 170.712 1.00 84.71  ? 550 LYS A CE  1 
ATOM 3026 N NZ  . LYS A 1 380 ? 142.893 167.471 170.432 1.00 87.06  ? 550 LYS A NZ  1 
ATOM 3027 N N   . HIS A 1 381 ? 150.261 166.613 168.506 1.00 74.88  ? 551 HIS A N   1 
ATOM 3028 C CA  . HIS A 1 381 ? 150.759 165.959 167.291 1.00 74.94  ? 551 HIS A CA  1 
ATOM 3029 C C   . HIS A 1 381 ? 152.249 165.957 166.988 1.00 75.60  ? 551 HIS A C   1 
ATOM 3030 O O   . HIS A 1 381 ? 152.621 165.558 165.879 1.00 76.29  ? 551 HIS A O   1 
ATOM 3031 C CB  . HIS A 1 381 ? 150.092 166.628 166.084 1.00 74.22  ? 551 HIS A CB  1 
ATOM 3032 C CG  . HIS A 1 381 ? 148.615 166.770 166.219 1.00 74.13  ? 551 HIS A CG  1 
ATOM 3033 N ND1 . HIS A 1 381 ? 147.771 165.681 166.337 1.00 73.99  ? 551 HIS A ND1 1 
ATOM 3034 C CD2 . HIS A 1 381 ? 147.829 167.868 166.260 1.00 72.81  ? 551 HIS A CD2 1 
ATOM 3035 C CE1 . HIS A 1 381 ? 146.527 166.111 166.443 1.00 73.32  ? 551 HIS A CE1 1 
ATOM 3036 N NE2 . HIS A 1 381 ? 146.533 167.432 166.394 1.00 72.86  ? 551 HIS A NE2 1 
ATOM 3037 N N   . TRP A 1 382 ? 153.106 166.439 167.890 1.00 75.59  ? 552 TRP A N   1 
ATOM 3038 C CA  . TRP A 1 382 ? 154.543 166.503 167.565 1.00 75.61  ? 552 TRP A CA  1 
ATOM 3039 C C   . TRP A 1 382 ? 155.130 165.189 167.053 1.00 76.74  ? 552 TRP A C   1 
ATOM 3040 O O   . TRP A 1 382 ? 156.026 165.190 166.215 1.00 76.94  ? 552 TRP A O   1 
ATOM 3041 C CB  . TRP A 1 382 ? 155.357 167.044 168.738 1.00 74.72  ? 552 TRP A CB  1 
ATOM 3042 C CG  . TRP A 1 382 ? 155.495 166.058 169.846 1.00 72.64  ? 552 TRP A CG  1 
ATOM 3043 C CD1 . TRP A 1 382 ? 154.585 165.787 170.819 1.00 71.29  ? 552 TRP A CD1 1 
ATOM 3044 C CD2 . TRP A 1 382 ? 156.603 165.190 170.072 1.00 71.20  ? 552 TRP A CD2 1 
ATOM 3045 N NE1 . TRP A 1 382 ? 155.062 164.797 171.642 1.00 71.23  ? 552 TRP A NE1 1 
ATOM 3046 C CE2 . TRP A 1 382 ? 156.300 164.413 171.204 1.00 70.67  ? 552 TRP A CE2 1 
ATOM 3047 C CE3 . TRP A 1 382 ? 157.822 164.984 169.417 1.00 72.03  ? 552 TRP A CE3 1 
ATOM 3048 C CZ2 . TRP A 1 382 ? 157.183 163.455 171.717 1.00 72.36  ? 552 TRP A CZ2 1 
ATOM 3049 C CZ3 . TRP A 1 382 ? 158.708 164.023 169.934 1.00 72.67  ? 552 TRP A CZ3 1 
ATOM 3050 C CH2 . TRP A 1 382 ? 158.379 163.276 171.068 1.00 71.81  ? 552 TRP A CH2 1 
ATOM 3051 N N   . ASP A 1 383 ? 154.609 164.077 167.540 1.00 78.18  ? 553 ASP A N   1 
ATOM 3052 C CA  . ASP A 1 383 ? 155.088 162.768 167.126 1.00 80.53  ? 553 ASP A CA  1 
ATOM 3053 C C   . ASP A 1 383 ? 154.065 162.039 166.233 1.00 81.78  ? 553 ASP A C   1 
ATOM 3054 O O   . ASP A 1 383 ? 153.976 160.807 166.274 1.00 81.98  ? 553 ASP A O   1 
ATOM 3055 C CB  . ASP A 1 383 ? 155.380 161.927 168.375 1.00 80.53  ? 553 ASP A CB  1 
ATOM 3056 C CG  . ASP A 1 383 ? 154.156 161.784 169.297 1.00 82.26  ? 553 ASP A CG  1 
ATOM 3057 O OD1 . ASP A 1 383 ? 153.136 162.487 169.083 1.00 82.36  ? 553 ASP A OD1 1 
ATOM 3058 O OD2 . ASP A 1 383 ? 154.216 160.960 170.245 1.00 84.99  ? 553 ASP A OD2 1 
ATOM 3059 N N   . GLN A 1 384 ? 153.296 162.792 165.435 1.00 83.02  ? 554 GLN A N   1 
ATOM 3060 C CA  . GLN A 1 384 ? 152.256 162.193 164.583 1.00 84.49  ? 554 GLN A CA  1 
ATOM 3061 C C   . GLN A 1 384 ? 152.750 161.152 163.580 1.00 85.86  ? 554 GLN A C   1 
ATOM 3062 O O   . GLN A 1 384 ? 151.982 160.294 163.150 1.00 86.89  ? 554 GLN A O   1 
ATOM 3063 C CB  . GLN A 1 384 ? 151.381 163.257 163.904 1.00 83.92  ? 554 GLN A CB  1 
ATOM 3064 C CG  . GLN A 1 384 ? 152.102 164.162 162.903 1.00 84.36  ? 554 GLN A CG  1 
ATOM 3065 C CD  . GLN A 1 384 ? 152.038 163.662 161.467 1.00 84.13  ? 554 GLN A CD  1 
ATOM 3066 O OE1 . GLN A 1 384 ? 151.127 162.921 161.090 1.00 85.85  ? 554 GLN A OE1 1 
ATOM 3067 N NE2 . GLN A 1 384 ? 152.998 164.080 160.654 1.00 82.23  ? 554 GLN A NE2 1 
ATOM 3068 N N   . ASP A 1 385 ? 154.025 161.238 163.212 1.00 87.07  ? 555 ASP A N   1 
ATOM 3069 C CA  . ASP A 1 385 ? 154.632 160.333 162.248 1.00 88.14  ? 555 ASP A CA  1 
ATOM 3070 C C   . ASP A 1 385 ? 155.462 159.192 162.844 1.00 88.74  ? 555 ASP A C   1 
ATOM 3071 O O   . ASP A 1 385 ? 156.123 158.459 162.093 1.00 88.71  ? 555 ASP A O   1 
ATOM 3072 C CB  . ASP A 1 385 ? 155.470 161.137 161.236 1.00 88.22  ? 555 ASP A CB  1 
ATOM 3073 C CG  . ASP A 1 385 ? 156.654 161.888 161.881 1.00 90.46  ? 555 ASP A CG  1 
ATOM 3074 O OD1 . ASP A 1 385 ? 156.584 162.327 163.057 1.00 94.43  ? 555 ASP A OD1 1 
ATOM 3075 O OD2 . ASP A 1 385 ? 157.672 162.071 161.187 1.00 91.27  ? 555 ASP A OD2 1 
ATOM 3076 N N   . ASP A 1 386 ? 155.434 159.024 164.171 1.00 89.63  ? 556 ASP A N   1 
ATOM 3077 C CA  . ASP A 1 386 ? 156.225 157.957 164.817 1.00 90.48  ? 556 ASP A CA  1 
ATOM 3078 C C   . ASP A 1 386 ? 155.914 156.538 164.328 1.00 90.09  ? 556 ASP A C   1 
ATOM 3079 O O   . ASP A 1 386 ? 156.822 155.719 164.204 1.00 90.14  ? 556 ASP A O   1 
ATOM 3080 C CB  . ASP A 1 386 ? 156.193 158.051 166.353 1.00 91.43  ? 556 ASP A CB  1 
ATOM 3081 C CG  . ASP A 1 386 ? 157.104 159.185 166.913 1.00 95.19  ? 556 ASP A CG  1 
ATOM 3082 O OD1 . ASP A 1 386 ? 157.638 160.028 166.125 1.00 98.03  ? 556 ASP A OD1 1 
ATOM 3083 O OD2 . ASP A 1 386 ? 157.269 159.246 168.164 1.00 98.30  ? 556 ASP A OD2 1 
ATOM 3084 N N   . ASP A 1 387 ? 154.650 156.261 164.022 1.00 89.75  ? 557 ASP A N   1 
ATOM 3085 C CA  . ASP A 1 387 ? 154.240 154.939 163.533 1.00 89.85  ? 557 ASP A CA  1 
ATOM 3086 C C   . ASP A 1 387 ? 154.799 154.542 162.156 1.00 88.79  ? 557 ASP A C   1 
ATOM 3087 O O   . ASP A 1 387 ? 154.710 153.379 161.757 1.00 88.84  ? 557 ASP A O   1 
ATOM 3088 C CB  . ASP A 1 387 ? 152.705 154.828 163.491 1.00 90.70  ? 557 ASP A CB  1 
ATOM 3089 C CG  . ASP A 1 387 ? 152.068 154.738 164.886 1.00 93.77  ? 557 ASP A CG  1 
ATOM 3090 O OD1 . ASP A 1 387 ? 152.692 154.214 165.855 1.00 96.23  ? 557 ASP A OD1 1 
ATOM 3091 O OD2 . ASP A 1 387 ? 150.912 155.198 165.004 1.00 97.49  ? 557 ASP A OD2 1 
ATOM 3092 N N   . PHE A 1 388 ? 155.365 155.502 161.428 1.00 87.47  ? 558 PHE A N   1 
ATOM 3093 C CA  . PHE A 1 388 ? 155.893 155.228 160.103 1.00 86.00  ? 558 PHE A CA  1 
ATOM 3094 C C   . PHE A 1 388 ? 157.398 155.039 160.053 1.00 85.65  ? 558 PHE A C   1 
ATOM 3095 O O   . PHE A 1 388 ? 157.967 154.976 158.975 1.00 85.95  ? 558 PHE A O   1 
ATOM 3096 C CB  . PHE A 1 388 ? 155.413 156.299 159.117 1.00 85.54  ? 558 PHE A CB  1 
ATOM 3097 C CG  . PHE A 1 388 ? 153.927 156.404 159.059 1.00 85.03  ? 558 PHE A CG  1 
ATOM 3098 C CD1 . PHE A 1 388 ? 153.182 155.490 158.316 1.00 84.30  ? 558 PHE A CD1 1 
ATOM 3099 C CD2 . PHE A 1 388 ? 153.259 157.377 159.792 1.00 85.11  ? 558 PHE A CD2 1 
ATOM 3100 C CE1 . PHE A 1 388 ? 151.798 155.556 158.289 1.00 83.95  ? 558 PHE A CE1 1 
ATOM 3101 C CE2 . PHE A 1 388 ? 151.866 157.450 159.770 1.00 85.07  ? 558 PHE A CE2 1 
ATOM 3102 C CZ  . PHE A 1 388 ? 151.138 156.536 159.019 1.00 84.72  ? 558 PHE A CZ  1 
ATOM 3103 N N   . GLU A 1 389 ? 158.038 154.927 161.209 1.00 85.09  ? 559 GLU A N   1 
ATOM 3104 C CA  . GLU A 1 389 ? 159.491 154.742 161.263 1.00 85.22  ? 559 GLU A CA  1 
ATOM 3105 C C   . GLU A 1 389 ? 159.981 153.480 160.566 1.00 82.98  ? 559 GLU A C   1 
ATOM 3106 O O   . GLU A 1 389 ? 159.326 152.433 160.598 1.00 82.99  ? 559 GLU A O   1 
ATOM 3107 C CB  . GLU A 1 389 ? 160.006 154.793 162.706 1.00 85.32  ? 559 GLU A CB  1 
ATOM 3108 C CG  . GLU A 1 389 ? 160.419 156.214 163.153 1.00 87.85  ? 559 GLU A CG  1 
ATOM 3109 C CD  . GLU A 1 389 ? 160.750 156.317 164.666 1.00 89.55  ? 559 GLU A CD  1 
ATOM 3110 O OE1 . GLU A 1 389 ? 161.151 155.278 165.305 1.00 90.84  ? 559 GLU A OE1 1 
ATOM 3111 O OE2 . GLU A 1 389 ? 160.596 157.463 165.201 1.00 94.50  ? 559 GLU A OE2 1 
ATOM 3112 N N   . PHE A 1 390 ? 161.137 153.604 159.926 1.00 80.99  ? 560 PHE A N   1 
ATOM 3113 C CA  . PHE A 1 390 ? 161.750 152.492 159.221 1.00 79.13  ? 560 PHE A CA  1 
ATOM 3114 C C   . PHE A 1 390 ? 162.493 151.588 160.200 1.00 78.63  ? 560 PHE A C   1 
ATOM 3115 O O   . PHE A 1 390 ? 162.765 151.979 161.334 1.00 79.05  ? 560 PHE A O   1 
ATOM 3116 C CB  . PHE A 1 390 ? 162.738 153.011 158.183 1.00 78.50  ? 560 PHE A CB  1 
ATOM 3117 C CG  . PHE A 1 390 ? 162.130 153.892 157.141 1.00 76.90  ? 560 PHE A CG  1 
ATOM 3118 C CD1 . PHE A 1 390 ? 160.889 153.600 156.587 1.00 76.03  ? 560 PHE A CD1 1 
ATOM 3119 C CD2 . PHE A 1 390 ? 162.822 154.992 156.676 1.00 76.09  ? 560 PHE A CD2 1 
ATOM 3120 C CE1 . PHE A 1 390 ? 160.335 154.414 155.597 1.00 75.58  ? 560 PHE A CE1 1 
ATOM 3121 C CE2 . PHE A 1 390 ? 162.274 155.815 155.682 1.00 76.65  ? 560 PHE A CE2 1 
ATOM 3122 C CZ  . PHE A 1 390 ? 161.027 155.520 155.143 1.00 76.37  ? 560 PHE A CZ  1 
ATOM 3123 N N   . THR A 1 391 ? 162.829 150.382 159.764 1.00 77.65  ? 561 THR A N   1 
ATOM 3124 C CA  . THR A 1 391 ? 163.552 149.457 160.605 1.00 76.88  ? 561 THR A CA  1 
ATOM 3125 C C   . THR A 1 391 ? 165.012 149.394 160.179 1.00 76.87  ? 561 THR A C   1 
ATOM 3126 O O   . THR A 1 391 ? 165.377 149.847 159.093 1.00 76.56  ? 561 THR A O   1 
ATOM 3127 C CB  . THR A 1 391 ? 162.948 148.020 160.578 1.00 76.92  ? 561 THR A CB  1 
ATOM 3128 O OG1 . THR A 1 391 ? 163.050 147.459 159.263 1.00 76.15  ? 561 THR A OG1 1 
ATOM 3129 C CG2 . THR A 1 391 ? 161.496 148.024 161.046 1.00 76.73  ? 561 THR A CG2 1 
ATOM 3130 N N   . GLY A 1 392 ? 165.837 148.803 161.039 1.00 76.92  ? 562 GLY A N   1 
ATOM 3131 C CA  . GLY A 1 392 ? 167.259 148.658 160.768 1.00 76.85  ? 562 GLY A CA  1 
ATOM 3132 C C   . GLY A 1 392 ? 168.013 149.769 161.450 1.00 76.90  ? 562 GLY A C   1 
ATOM 3133 O O   . GLY A 1 392 ? 167.416 150.703 162.000 1.00 76.58  ? 562 GLY A O   1 
ATOM 3134 N N   . SER A 1 393 ? 169.332 149.670 161.411 1.00 77.07  ? 563 SER A N   1 
ATOM 3135 C CA  . SER A 1 393 ? 170.178 150.661 162.047 1.00 77.63  ? 563 SER A CA  1 
ATOM 3136 C C   . SER A 1 393 ? 170.292 151.937 161.247 1.00 77.70  ? 563 SER A C   1 
ATOM 3137 O O   . SER A 1 393 ? 170.179 151.932 160.015 1.00 77.86  ? 563 SER A O   1 
ATOM 3138 C CB  . SER A 1 393 ? 171.570 150.074 162.324 1.00 78.04  ? 563 SER A CB  1 
ATOM 3139 O OG  . SER A 1 393 ? 172.244 149.741 161.114 1.00 79.31  ? 563 SER A OG  1 
ATOM 3140 N N   . HIS A 1 394 ? 170.513 153.032 161.967 1.00 77.81  ? 564 HIS A N   1 
ATOM 3141 C CA  . HIS A 1 394 ? 170.693 154.333 161.362 1.00 78.01  ? 564 HIS A CA  1 
ATOM 3142 C C   . HIS A 1 394 ? 172.085 154.343 160.732 1.00 77.16  ? 564 HIS A C   1 
ATOM 3143 O O   . HIS A 1 394 ? 173.004 153.677 161.220 1.00 77.23  ? 564 HIS A O   1 
ATOM 3144 C CB  . HIS A 1 394 ? 170.515 155.426 162.400 1.00 78.88  ? 564 HIS A CB  1 
ATOM 3145 C CG  . HIS A 1 394 ? 169.118 155.499 162.941 1.00 83.35  ? 564 HIS A CG  1 
ATOM 3146 N ND1 . HIS A 1 394 ? 168.149 156.321 162.402 1.00 85.92  ? 564 HIS A ND1 1 
ATOM 3147 C CD2 . HIS A 1 394 ? 168.517 154.822 163.951 1.00 87.13  ? 564 HIS A CD2 1 
ATOM 3148 C CE1 . HIS A 1 394 ? 167.014 156.156 163.056 1.00 86.81  ? 564 HIS A CE1 1 
ATOM 3149 N NE2 . HIS A 1 394 ? 167.210 155.251 164.000 1.00 89.74  ? 564 HIS A NE2 1 
ATOM 3150 N N   . LEU A 1 395 ? 172.223 155.050 159.616 1.00 76.05  ? 565 LEU A N   1 
ATOM 3151 C CA  . LEU A 1 395 ? 173.479 155.102 158.892 1.00 74.81  ? 565 LEU A CA  1 
ATOM 3152 C C   . LEU A 1 395 ? 173.819 156.516 158.463 1.00 74.20  ? 565 LEU A C   1 
ATOM 3153 O O   . LEU A 1 395 ? 172.958 157.390 158.478 1.00 74.22  ? 565 LEU A O   1 
ATOM 3154 C CB  . LEU A 1 395 ? 173.352 154.239 157.629 1.00 74.68  ? 565 LEU A CB  1 
ATOM 3155 C CG  . LEU A 1 395 ? 172.698 152.854 157.703 1.00 74.65  ? 565 LEU A CG  1 
ATOM 3156 C CD1 . LEU A 1 395 ? 171.955 152.549 156.435 1.00 75.02  ? 565 LEU A CD1 1 
ATOM 3157 C CD2 . LEU A 1 395 ? 173.718 151.764 157.963 1.00 74.67  ? 565 LEU A CD2 1 
ATOM 3158 N N   . THR A 1 396 ? 175.072 156.728 158.070 1.00 73.51  ? 566 THR A N   1 
ATOM 3159 C CA  . THR A 1 396 ? 175.526 158.016 157.559 1.00 73.15  ? 566 THR A CA  1 
ATOM 3160 C C   . THR A 1 396 ? 176.139 157.724 156.226 1.00 72.80  ? 566 THR A C   1 
ATOM 3161 O O   . THR A 1 396 ? 176.605 156.604 155.996 1.00 72.69  ? 566 THR A O   1 
ATOM 3162 C CB  . THR A 1 396 ? 176.607 158.700 158.405 1.00 73.22  ? 566 THR A CB  1 
ATOM 3163 O OG1 . THR A 1 396 ? 177.727 157.825 158.586 1.00 73.64  ? 566 THR A OG1 1 
ATOM 3164 C CG2 . THR A 1 396 ? 176.053 159.132 159.736 1.00 74.15  ? 566 THR A CG2 1 
ATOM 3165 N N   . VAL A 1 397 ? 176.155 158.730 155.356 1.00 72.70  ? 567 VAL A N   1 
ATOM 3166 C CA  . VAL A 1 397 ? 176.729 158.596 154.024 1.00 72.71  ? 567 VAL A CA  1 
ATOM 3167 C C   . VAL A 1 397 ? 178.200 158.973 154.113 1.00 72.97  ? 567 VAL A C   1 
ATOM 3168 O O   . VAL A 1 397 ? 178.552 160.143 154.146 1.00 73.29  ? 567 VAL A O   1 
ATOM 3169 C CB  . VAL A 1 397 ? 175.983 159.477 153.023 1.00 72.37  ? 567 VAL A CB  1 
ATOM 3170 C CG1 . VAL A 1 397 ? 176.348 159.078 151.608 1.00 72.51  ? 567 VAL A CG1 1 
ATOM 3171 C CG2 . VAL A 1 397 ? 174.506 159.334 153.236 1.00 71.52  ? 567 VAL A CG2 1 
ATOM 3172 N N   . ARG A 1 398 ? 179.055 157.967 154.188 1.00 73.53  ? 568 ARG A N   1 
ATOM 3173 C CA  . ARG A 1 398 ? 180.493 158.174 154.340 1.00 74.11  ? 568 ARG A CA  1 
ATOM 3174 C C   . ARG A 1 398 ? 181.152 159.030 153.272 1.00 74.09  ? 568 ARG A C   1 
ATOM 3175 O O   . ARG A 1 398 ? 182.113 159.741 153.562 1.00 74.32  ? 568 ARG A O   1 
ATOM 3176 C CB  . ARG A 1 398 ? 181.214 156.834 154.476 1.00 74.34  ? 568 ARG A CB  1 
ATOM 3177 C CG  . ARG A 1 398 ? 182.413 156.878 155.403 1.00 75.97  ? 568 ARG A CG  1 
ATOM 3178 C CD  . ARG A 1 398 ? 182.518 155.590 156.199 1.00 79.37  ? 568 ARG A CD  1 
ATOM 3179 N NE  . ARG A 1 398 ? 183.641 155.600 157.135 1.00 81.23  ? 568 ARG A NE  1 
ATOM 3180 C CZ  . ARG A 1 398 ? 184.888 155.283 156.796 1.00 82.43  ? 568 ARG A CZ  1 
ATOM 3181 N NH1 . ARG A 1 398 ? 185.171 154.940 155.536 1.00 83.00  ? 568 ARG A NH1 1 
ATOM 3182 N NH2 . ARG A 1 398 ? 185.851 155.317 157.706 1.00 82.44  ? 568 ARG A NH2 1 
ATOM 3183 N N   . ASN A 1 399 ? 180.635 158.976 152.046 1.00 73.95  ? 569 ASN A N   1 
ATOM 3184 C CA  . ASN A 1 399 ? 181.196 159.763 150.957 1.00 73.74  ? 569 ASN A CA  1 
ATOM 3185 C C   . ASN A 1 399 ? 180.438 161.071 150.677 1.00 73.39  ? 569 ASN A C   1 
ATOM 3186 O O   . ASN A 1 399 ? 180.657 161.717 149.647 1.00 73.20  ? 569 ASN A O   1 
ATOM 3187 C CB  . ASN A 1 399 ? 181.364 158.910 149.689 1.00 74.05  ? 569 ASN A CB  1 
ATOM 3188 C CG  . ASN A 1 399 ? 180.061 158.278 149.222 1.00 75.33  ? 569 ASN A CG  1 
ATOM 3189 O OD1 . ASN A 1 399 ? 179.208 157.889 150.037 1.00 76.33  ? 569 ASN A OD1 1 
ATOM 3190 N ND2 . ASN A 1 399 ? 179.900 158.169 147.899 1.00 74.99  ? 569 ASN A ND2 1 
ATOM 3191 N N   . GLY A 1 400 ? 179.577 161.473 151.610 1.00 72.84  ? 570 GLY A N   1 
ATOM 3192 C CA  . GLY A 1 400 ? 178.812 162.711 151.465 1.00 72.65  ? 570 GLY A CA  1 
ATOM 3193 C C   . GLY A 1 400 ? 177.493 162.483 150.759 1.00 72.54  ? 570 GLY A C   1 
ATOM 3194 O O   . GLY A 1 400 ? 177.450 161.919 149.656 1.00 72.99  ? 570 GLY A O   1 
ATOM 3195 N N   . TYR A 1 401 ? 176.402 162.941 151.382 1.00 71.84  ? 571 TYR A N   1 
ATOM 3196 C CA  . TYR A 1 401 ? 175.043 162.710 150.823 1.00 71.48  ? 571 TYR A CA  1 
ATOM 3197 C C   . TYR A 1 401 ? 174.907 163.304 149.418 1.00 71.79  ? 571 TYR A C   1 
ATOM 3198 O O   . TYR A 1 401 ? 174.155 162.725 148.609 1.00 72.17  ? 571 TYR A O   1 
ATOM 3199 C CB  . TYR A 1 401 ? 173.991 163.321 151.753 1.00 70.99  ? 571 TYR A CB  1 
ATOM 3200 C CG  . TYR A 1 401 ? 172.703 162.545 151.860 1.00 70.32  ? 571 TYR A CG  1 
ATOM 3201 C CD1 . TYR A 1 401 ? 171.857 162.405 150.773 1.00 70.30  ? 571 TYR A CD1 1 
ATOM 3202 C CD2 . TYR A 1 401 ? 172.323 161.957 153.055 1.00 68.83  ? 571 TYR A CD2 1 
ATOM 3203 C CE1 . TYR A 1 401 ? 170.672 161.695 150.866 1.00 70.74  ? 571 TYR A CE1 1 
ATOM 3204 C CE2 . TYR A 1 401 ? 171.142 161.244 153.167 1.00 68.87  ? 571 TYR A CE2 1 
ATOM 3205 C CZ  . TYR A 1 401 ? 170.312 161.112 152.068 1.00 70.36  ? 571 TYR A CZ  1 
ATOM 3206 O OH  . TYR A 1 401 ? 169.146 160.410 152.171 1.00 70.35  ? 571 TYR A OH  1 
ATOM 3207 N N   . SER A 1 402 ? 175.593 164.415 149.132 1.00 71.75  ? 572 SER A N   1 
ATOM 3208 C CA  . SER A 1 402 ? 175.422 165.078 147.842 1.00 71.59  ? 572 SER A CA  1 
ATOM 3209 C C   . SER A 1 402 ? 175.555 164.133 146.655 1.00 71.50  ? 572 SER A C   1 
ATOM 3210 O O   . SER A 1 402 ? 175.118 164.470 145.557 1.00 71.90  ? 572 SER A O   1 
ATOM 3211 C CB  . SER A 1 402 ? 176.376 166.257 147.683 1.00 71.74  ? 572 SER A CB  1 
ATOM 3212 O OG  . SER A 1 402 ? 177.689 165.810 147.409 1.00 72.13  ? 572 SER A OG  1 
ATOM 3213 N N   . CYS A 1 403 ? 176.139 162.956 146.858 1.00 71.28  ? 573 CYS A N   1 
ATOM 3214 C CA  . CYS A 1 403 ? 176.286 162.006 145.751 1.00 71.45  ? 573 CYS A CA  1 
ATOM 3215 C C   . CYS A 1 403 ? 174.925 161.620 145.175 1.00 70.64  ? 573 CYS A C   1 
ATOM 3216 O O   . CYS A 1 403 ? 174.829 161.283 143.990 1.00 70.86  ? 573 CYS A O   1 
ATOM 3217 C CB  . CYS A 1 403 ? 177.072 160.762 146.164 1.00 71.63  ? 573 CYS A CB  1 
ATOM 3218 S SG  . CYS A 1 403 ? 176.296 159.776 147.477 1.00 76.82  ? 573 CYS A SG  1 
ATOM 3219 N N   . VAL A 1 404 ? 173.882 161.697 146.005 1.00 69.74  ? 574 VAL A N   1 
ATOM 3220 C CA  . VAL A 1 404 ? 172.521 161.368 145.588 1.00 68.68  ? 574 VAL A CA  1 
ATOM 3221 C C   . VAL A 1 404 ? 171.946 162.403 144.596 1.00 68.64  ? 574 VAL A C   1 
ATOM 3222 O O   . VAL A 1 404 ? 171.707 162.067 143.435 1.00 68.47  ? 574 VAL A O   1 
ATOM 3223 C CB  . VAL A 1 404 ? 171.603 161.124 146.803 1.00 68.83  ? 574 VAL A CB  1 
ATOM 3224 C CG1 . VAL A 1 404 ? 170.125 161.074 146.394 1.00 67.75  ? 574 VAL A CG1 1 
ATOM 3225 C CG2 . VAL A 1 404 ? 172.023 159.841 147.532 1.00 67.78  ? 574 VAL A CG2 1 
ATOM 3226 N N   . PRO A 1 405 ? 171.750 163.667 145.030 1.00 68.16  ? 575 PRO A N   1 
ATOM 3227 C CA  . PRO A 1 405 ? 171.241 164.658 144.078 1.00 67.57  ? 575 PRO A CA  1 
ATOM 3228 C C   . PRO A 1 405 ? 172.132 164.802 142.847 1.00 67.67  ? 575 PRO A C   1 
ATOM 3229 O O   . PRO A 1 405 ? 171.626 164.882 141.714 1.00 68.38  ? 575 PRO A O   1 
ATOM 3230 C CB  . PRO A 1 405 ? 171.241 165.956 144.876 1.00 67.06  ? 575 PRO A CB  1 
ATOM 3231 C CG  . PRO A 1 405 ? 172.092 165.697 146.064 1.00 67.72  ? 575 PRO A CG  1 
ATOM 3232 C CD  . PRO A 1 405 ? 171.969 164.252 146.363 1.00 67.60  ? 575 PRO A CD  1 
ATOM 3233 N N   . VAL A 1 406 ? 173.442 164.825 143.040 1.00 67.13  ? 576 VAL A N   1 
ATOM 3234 C CA  . VAL A 1 406 ? 174.327 164.951 141.887 1.00 66.79  ? 576 VAL A CA  1 
ATOM 3235 C C   . VAL A 1 406 ? 174.000 163.843 140.880 1.00 67.04  ? 576 VAL A C   1 
ATOM 3236 O O   . VAL A 1 406 ? 173.904 164.109 139.694 1.00 67.37  ? 576 VAL A O   1 
ATOM 3237 C CB  . VAL A 1 406 ? 175.830 164.956 142.281 1.00 66.68  ? 576 VAL A CB  1 
ATOM 3238 C CG1 . VAL A 1 406 ? 176.722 164.769 141.049 1.00 65.51  ? 576 VAL A CG1 1 
ATOM 3239 C CG2 . VAL A 1 406 ? 176.191 166.251 143.022 1.00 64.66  ? 576 VAL A CG2 1 
ATOM 3240 N N   . ALA A 1 407 ? 173.788 162.617 141.359 1.00 67.34  ? 577 ALA A N   1 
ATOM 3241 C CA  . ALA A 1 407 ? 173.452 161.494 140.474 1.00 67.72  ? 577 ALA A CA  1 
ATOM 3242 C C   . ALA A 1 407 ? 172.061 161.646 139.850 1.00 68.38  ? 577 ALA A C   1 
ATOM 3243 O O   . ALA A 1 407 ? 171.875 161.356 138.650 1.00 69.13  ? 577 ALA A O   1 
ATOM 3244 C CB  . ALA A 1 407 ? 173.551 160.183 141.202 1.00 67.28  ? 577 ALA A CB  1 
ATOM 3245 N N   . LEU A 1 408 ? 171.090 162.088 140.653 1.00 68.13  ? 578 LEU A N   1 
ATOM 3246 C CA  . LEU A 1 408 ? 169.730 162.271 140.170 1.00 68.18  ? 578 LEU A CA  1 
ATOM 3247 C C   . LEU A 1 408 ? 169.666 163.345 139.099 1.00 68.75  ? 578 LEU A C   1 
ATOM 3248 O O   . LEU A 1 408 ? 168.793 163.299 138.251 1.00 69.47  ? 578 LEU A O   1 
ATOM 3249 C CB  . LEU A 1 408 ? 168.755 162.578 141.308 1.00 68.05  ? 578 LEU A CB  1 
ATOM 3250 C CG  . LEU A 1 408 ? 168.474 161.441 142.301 1.00 67.20  ? 578 LEU A CG  1 
ATOM 3251 C CD1 . LEU A 1 408 ? 167.598 161.946 143.383 1.00 65.11  ? 578 LEU A CD1 1 
ATOM 3252 C CD2 . LEU A 1 408 ? 167.847 160.219 141.647 1.00 66.02  ? 578 LEU A CD2 1 
ATOM 3253 N N   . ALA A 1 409 ? 170.617 164.275 139.110 1.00 69.11  ? 579 ALA A N   1 
ATOM 3254 C CA  . ALA A 1 409 ? 170.671 165.349 138.121 1.00 69.31  ? 579 ALA A CA  1 
ATOM 3255 C C   . ALA A 1 409 ? 171.118 164.911 136.712 1.00 69.84  ? 579 ALA A C   1 
ATOM 3256 O O   . ALA A 1 409 ? 170.902 165.632 135.734 1.00 69.85  ? 579 ALA A O   1 
ATOM 3257 C CB  . ALA A 1 409 ? 171.558 166.462 138.627 1.00 69.00  ? 579 ALA A CB  1 
ATOM 3258 N N   . GLU A 1 410 ? 171.747 163.745 136.597 1.00 70.60  ? 580 GLU A N   1 
ATOM 3259 C CA  . GLU A 1 410 ? 172.233 163.271 135.294 1.00 71.53  ? 580 GLU A CA  1 
ATOM 3260 C C   . GLU A 1 410 ? 171.175 163.285 134.194 1.00 71.07  ? 580 GLU A C   1 
ATOM 3261 O O   . GLU A 1 410 ? 170.128 162.671 134.325 1.00 71.96  ? 580 GLU A O   1 
ATOM 3262 C CB  . GLU A 1 410 ? 172.847 161.866 135.412 1.00 71.24  ? 580 GLU A CB  1 
ATOM 3263 C CG  . GLU A 1 410 ? 173.035 161.132 134.070 1.00 73.07  ? 580 GLU A CG  1 
ATOM 3264 C CD  . GLU A 1 410 ? 174.034 159.977 134.135 1.00 73.90  ? 580 GLU A CD  1 
ATOM 3265 O OE1 . GLU A 1 410 ? 174.144 159.329 135.201 1.00 78.66  ? 580 GLU A OE1 1 
ATOM 3266 O OE2 . GLU A 1 410 ? 174.713 159.708 133.116 1.00 77.19  ? 580 GLU A OE2 1 
ATOM 3267 N N   . GLY A 1 411 ? 171.454 163.979 133.104 1.00 70.80  ? 581 GLY A N   1 
ATOM 3268 C CA  . GLY A 1 411 ? 170.518 164.014 131.987 1.00 70.19  ? 581 GLY A CA  1 
ATOM 3269 C C   . GLY A 1 411 ? 169.331 164.944 132.074 1.00 69.81  ? 581 GLY A C   1 
ATOM 3270 O O   . GLY A 1 411 ? 168.504 164.961 131.165 1.00 70.23  ? 581 GLY A O   1 
ATOM 3271 N N   . LEU A 1 412 ? 169.243 165.729 133.140 1.00 69.24  ? 582 LEU A N   1 
ATOM 3272 C CA  . LEU A 1 412 ? 168.146 166.668 133.306 1.00 68.90  ? 582 LEU A CA  1 
ATOM 3273 C C   . LEU A 1 412 ? 168.553 168.056 132.833 1.00 68.92  ? 582 LEU A C   1 
ATOM 3274 O O   . LEU A 1 412 ? 169.732 168.368 132.796 1.00 69.15  ? 582 LEU A O   1 
ATOM 3275 C CB  . LEU A 1 412 ? 167.708 166.736 134.772 1.00 68.62  ? 582 LEU A CB  1 
ATOM 3276 C CG  . LEU A 1 412 ? 167.074 165.479 135.358 1.00 68.66  ? 582 LEU A CG  1 
ATOM 3277 C CD1 . LEU A 1 412 ? 166.766 165.657 136.825 1.00 67.03  ? 582 LEU A CD1 1 
ATOM 3278 C CD2 . LEU A 1 412 ? 165.805 165.079 134.582 1.00 68.63  ? 582 LEU A CD2 1 
ATOM 3279 N N   . ASP A 1 413 ? 167.569 168.882 132.485 1.00 69.15  ? 583 ASP A N   1 
ATOM 3280 C CA  . ASP A 1 413 ? 167.792 170.257 132.037 1.00 69.32  ? 583 ASP A CA  1 
ATOM 3281 C C   . ASP A 1 413 ? 167.687 171.158 133.259 1.00 69.03  ? 583 ASP A C   1 
ATOM 3282 O O   . ASP A 1 413 ? 166.580 171.542 133.671 1.00 69.40  ? 583 ASP A O   1 
ATOM 3283 C CB  . ASP A 1 413 ? 166.728 170.655 131.009 1.00 69.56  ? 583 ASP A CB  1 
ATOM 3284 C CG  . ASP A 1 413 ? 166.961 172.040 130.415 1.00 71.52  ? 583 ASP A CG  1 
ATOM 3285 O OD1 . ASP A 1 413 ? 168.115 172.537 130.392 1.00 73.97  ? 583 ASP A OD1 1 
ATOM 3286 O OD2 . ASP A 1 413 ? 165.976 172.638 129.936 1.00 74.81  ? 583 ASP A OD2 1 
ATOM 3287 N N   . ILE A 1 414 ? 168.825 171.485 133.859 1.00 68.23  ? 584 ILE A N   1 
ATOM 3288 C CA  . ILE A 1 414 ? 168.795 172.321 135.045 1.00 67.77  ? 584 ILE A CA  1 
ATOM 3289 C C   . ILE A 1 414 ? 169.389 173.700 134.816 1.00 67.81  ? 584 ILE A C   1 
ATOM 3290 O O   . ILE A 1 414 ? 170.500 173.811 134.321 1.00 68.20  ? 584 ILE A O   1 
ATOM 3291 C CB  . ILE A 1 414 ? 169.530 171.623 136.225 1.00 67.69  ? 584 ILE A CB  1 
ATOM 3292 C CG1 . ILE A 1 414 ? 168.879 170.278 136.533 1.00 66.73  ? 584 ILE A CG1 1 
ATOM 3293 C CG2 . ILE A 1 414 ? 169.519 172.490 137.475 1.00 66.78  ? 584 ILE A CG2 1 
ATOM 3294 C CD1 . ILE A 1 414 ? 169.791 169.340 137.273 1.00 66.53  ? 584 ILE A CD1 1 
ATOM 3295 N N   . LYS A 1 415 ? 168.657 174.748 135.190 1.00 67.67  ? 585 LYS A N   1 
ATOM 3296 C CA  . LYS A 1 415 ? 169.165 176.117 135.052 1.00 67.16  ? 585 LYS A CA  1 
ATOM 3297 C C   . LYS A 1 415 ? 169.584 176.574 136.430 1.00 67.09  ? 585 LYS A C   1 
ATOM 3298 O O   . LYS A 1 415 ? 168.736 176.901 137.253 1.00 67.04  ? 585 LYS A O   1 
ATOM 3299 C CB  . LYS A 1 415 ? 168.103 177.077 134.517 1.00 67.22  ? 585 LYS A CB  1 
ATOM 3300 C CG  . LYS A 1 415 ? 167.383 176.625 133.265 1.00 67.81  ? 585 LYS A CG  1 
ATOM 3301 C CD  . LYS A 1 415 ? 168.327 176.386 132.110 1.00 69.31  ? 585 LYS A CD  1 
ATOM 3302 C CE  . LYS A 1 415 ? 167.539 176.082 130.851 1.00 71.92  ? 585 LYS A CE  1 
ATOM 3303 N NZ  . LYS A 1 415 ? 168.430 175.526 129.805 1.00 73.26  ? 585 LYS A NZ  1 
ATOM 3304 N N   . LEU A 1 416 ? 170.892 176.579 136.682 1.00 67.08  ? 586 LEU A N   1 
ATOM 3305 C CA  . LEU A 1 416 ? 171.446 177.005 137.966 1.00 66.94  ? 586 LEU A CA  1 
ATOM 3306 C C   . LEU A 1 416 ? 171.476 178.530 138.021 1.00 66.98  ? 586 LEU A C   1 
ATOM 3307 O O   . LEU A 1 416 ? 171.295 179.177 136.989 1.00 67.00  ? 586 LEU A O   1 
ATOM 3308 C CB  . LEU A 1 416 ? 172.848 176.406 138.168 1.00 66.91  ? 586 LEU A CB  1 
ATOM 3309 C CG  . LEU A 1 416 ? 172.880 174.865 138.264 1.00 66.90  ? 586 LEU A CG  1 
ATOM 3310 C CD1 . LEU A 1 416 ? 174.291 174.320 138.296 1.00 65.89  ? 586 LEU A CD1 1 
ATOM 3311 C CD2 . LEU A 1 416 ? 172.084 174.359 139.461 1.00 65.19  ? 586 LEU A CD2 1 
ATOM 3312 N N   . ASN A 1 417 ? 171.668 179.106 139.210 1.00 66.74  ? 587 ASN A N   1 
ATOM 3313 C CA  . ASN A 1 417 ? 171.712 180.568 139.369 1.00 66.84  ? 587 ASN A CA  1 
ATOM 3314 C C   . ASN A 1 417 ? 170.540 181.311 138.742 1.00 67.27  ? 587 ASN A C   1 
ATOM 3315 O O   . ASN A 1 417 ? 170.698 182.400 138.182 1.00 67.63  ? 587 ASN A O   1 
ATOM 3316 C CB  . ASN A 1 417 ? 173.015 181.103 138.808 1.00 66.53  ? 587 ASN A CB  1 
ATOM 3317 C CG  . ASN A 1 417 ? 174.198 180.436 139.425 1.00 66.89  ? 587 ASN A CG  1 
ATOM 3318 O OD1 . ASN A 1 417 ? 174.370 180.463 140.653 1.00 67.61  ? 587 ASN A OD1 1 
ATOM 3319 N ND2 . ASN A 1 417 ? 174.999 179.790 138.602 1.00 66.17  ? 587 ASN A ND2 1 
ATOM 3320 N N   . THR A 1 418 ? 169.369 180.701 138.853 1.00 67.37  ? 588 THR A N   1 
ATOM 3321 C CA  . THR A 1 418 ? 168.150 181.229 138.310 1.00 67.36  ? 588 THR A CA  1 
ATOM 3322 C C   . THR A 1 418 ? 167.152 181.268 139.452 1.00 67.53  ? 588 THR A C   1 
ATOM 3323 O O   . THR A 1 418 ? 166.614 180.236 139.849 1.00 67.35  ? 588 THR A O   1 
ATOM 3324 C CB  . THR A 1 418 ? 167.652 180.273 137.217 1.00 67.69  ? 588 THR A CB  1 
ATOM 3325 O OG1 . THR A 1 418 ? 168.706 180.040 136.274 1.00 66.41  ? 588 THR A OG1 1 
ATOM 3326 C CG2 . THR A 1 418 ? 166.425 180.820 136.504 1.00 67.60  ? 588 THR A CG2 1 
ATOM 3327 N N   . ALA A 1 419 ? 166.925 182.459 140.000 1.00 67.75  ? 589 ALA A N   1 
ATOM 3328 C CA  . ALA A 1 419 ? 165.989 182.613 141.117 1.00 67.64  ? 589 ALA A CA  1 
ATOM 3329 C C   . ALA A 1 419 ? 164.616 183.024 140.617 1.00 67.96  ? 589 ALA A C   1 
ATOM 3330 O O   . ALA A 1 419 ? 164.450 184.087 140.004 1.00 67.99  ? 589 ALA A O   1 
ATOM 3331 C CB  . ALA A 1 419 ? 166.506 183.631 142.114 1.00 67.25  ? 589 ALA A CB  1 
ATOM 3332 N N   . VAL A 1 420 ? 163.630 182.179 140.889 1.00 68.09  ? 590 VAL A N   1 
ATOM 3333 C CA  . VAL A 1 420 ? 162.269 182.452 140.501 1.00 68.36  ? 590 VAL A CA  1 
ATOM 3334 C C   . VAL A 1 420 ? 161.773 183.611 141.354 1.00 68.79  ? 590 VAL A C   1 
ATOM 3335 O O   . VAL A 1 420 ? 161.988 183.626 142.563 1.00 69.14  ? 590 VAL A O   1 
ATOM 3336 C CB  . VAL A 1 420 ? 161.381 181.204 140.702 1.00 68.54  ? 590 VAL A CB  1 
ATOM 3337 C CG1 . VAL A 1 420 ? 159.879 181.547 140.537 1.00 67.47  ? 590 VAL A CG1 1 
ATOM 3338 C CG2 . VAL A 1 420 ? 161.794 180.123 139.716 1.00 68.46  ? 590 VAL A CG2 1 
ATOM 3339 N N   . ARG A 1 421 ? 161.128 184.579 140.714 1.00 69.17  ? 591 ARG A N   1 
ATOM 3340 C CA  . ARG A 1 421 ? 160.586 185.746 141.397 1.00 69.66  ? 591 ARG A CA  1 
ATOM 3341 C C   . ARG A 1 421 ? 159.063 185.743 141.376 1.00 69.32  ? 591 ARG A C   1 
ATOM 3342 O O   . ARG A 1 421 ? 158.416 186.211 142.315 1.00 69.46  ? 591 ARG A O   1 
ATOM 3343 C CB  . ARG A 1 421 ? 161.057 187.019 140.696 1.00 70.46  ? 591 ARG A CB  1 
ATOM 3344 C CG  . ARG A 1 421 ? 162.538 187.327 140.820 1.00 73.54  ? 591 ARG A CG  1 
ATOM 3345 C CD  . ARG A 1 421 ? 162.828 188.182 142.025 1.00 79.22  ? 591 ARG A CD  1 
ATOM 3346 N NE  . ARG A 1 421 ? 163.872 189.162 141.712 1.00 85.91  ? 591 ARG A NE  1 
ATOM 3347 C CZ  . ARG A 1 421 ? 165.126 189.097 142.160 1.00 88.27  ? 591 ARG A CZ  1 
ATOM 3348 N NH1 . ARG A 1 421 ? 165.507 188.086 142.962 1.00 91.04  ? 591 ARG A NH1 1 
ATOM 3349 N NH2 . ARG A 1 421 ? 165.993 190.039 141.814 1.00 86.04  ? 591 ARG A NH2 1 
ATOM 3350 N N   . GLN A 1 422 ? 158.490 185.241 140.288 1.00 68.65  ? 592 GLN A N   1 
ATOM 3351 C CA  . GLN A 1 422 ? 157.055 185.242 140.134 1.00 68.05  ? 592 GLN A CA  1 
ATOM 3352 C C   . GLN A 1 422 ? 156.507 184.012 139.417 1.00 67.81  ? 592 GLN A C   1 
ATOM 3353 O O   . GLN A 1 422 ? 157.081 183.526 138.441 1.00 67.54  ? 592 GLN A O   1 
ATOM 3354 C CB  . GLN A 1 422 ? 156.668 186.508 139.371 1.00 68.11  ? 592 GLN A CB  1 
ATOM 3355 C CG  . GLN A 1 422 ? 155.175 186.717 139.199 1.00 68.04  ? 592 GLN A CG  1 
ATOM 3356 C CD  . GLN A 1 422 ? 154.841 188.104 138.744 1.00 67.05  ? 592 GLN A CD  1 
ATOM 3357 O OE1 . GLN A 1 422 ? 154.249 188.283 137.677 1.00 70.38  ? 592 GLN A OE1 1 
ATOM 3358 N NE2 . GLN A 1 422 ? 155.200 189.102 139.545 1.00 64.30  ? 592 GLN A NE2 1 
ATOM 3359 N N   . VAL A 1 423 ? 155.370 183.525 139.897 1.00 67.80  ? 593 VAL A N   1 
ATOM 3360 C CA  . VAL A 1 423 ? 154.712 182.367 139.307 1.00 67.73  ? 593 VAL A CA  1 
ATOM 3361 C C   . VAL A 1 423 ? 153.302 182.781 138.912 1.00 67.89  ? 593 VAL A C   1 
ATOM 3362 O O   . VAL A 1 423 ? 152.487 183.143 139.775 1.00 67.37  ? 593 VAL A O   1 
ATOM 3363 C CB  . VAL A 1 423 ? 154.704 181.171 140.269 1.00 67.76  ? 593 VAL A CB  1 
ATOM 3364 C CG1 . VAL A 1 423 ? 153.826 180.052 139.745 1.00 68.10  ? 593 VAL A CG1 1 
ATOM 3365 C CG2 . VAL A 1 423 ? 156.094 180.658 140.452 1.00 67.77  ? 593 VAL A CG2 1 
ATOM 3366 N N   . ARG A 1 424 ? 153.053 182.780 137.600 1.00 68.47  ? 594 ARG A N   1 
ATOM 3367 C CA  . ARG A 1 424 ? 151.755 183.145 137.021 1.00 69.36  ? 594 ARG A CA  1 
ATOM 3368 C C   . ARG A 1 424 ? 151.082 181.893 136.486 1.00 69.74  ? 594 ARG A C   1 
ATOM 3369 O O   . ARG A 1 424 ? 151.671 181.148 135.695 1.00 70.32  ? 594 ARG A O   1 
ATOM 3370 C CB  . ARG A 1 424 ? 151.941 184.081 135.858 1.00 69.35  ? 594 ARG A CB  1 
ATOM 3371 C CG  . ARG A 1 424 ? 152.618 185.351 136.196 1.00 71.70  ? 594 ARG A CG  1 
ATOM 3372 C CD  . ARG A 1 424 ? 152.451 186.373 135.080 1.00 73.22  ? 594 ARG A CD  1 
ATOM 3373 N NE  . ARG A 1 424 ? 152.362 187.662 135.734 1.00 76.13  ? 594 ARG A NE  1 
ATOM 3374 C CZ  . ARG A 1 424 ? 151.286 188.433 135.757 1.00 76.76  ? 594 ARG A CZ  1 
ATOM 3375 N NH1 . ARG A 1 424 ? 150.191 188.106 135.090 1.00 75.63  ? 594 ARG A NH1 1 
ATOM 3376 N NH2 . ARG A 1 424 ? 151.337 189.568 136.431 1.00 80.04  ? 594 ARG A NH2 1 
ATOM 3377 N N   . TYR A 1 425 ? 149.853 181.643 136.911 1.00 69.88  ? 595 TYR A N   1 
ATOM 3378 C CA  . TYR A 1 425 ? 149.144 180.448 136.462 1.00 69.78  ? 595 TYR A CA  1 
ATOM 3379 C C   . TYR A 1 425 ? 147.731 180.813 136.037 1.00 70.04  ? 595 TYR A C   1 
ATOM 3380 O O   . TYR A 1 425 ? 146.993 181.457 136.776 1.00 70.48  ? 595 TYR A O   1 
ATOM 3381 C CB  . TYR A 1 425 ? 149.192 179.350 137.537 1.00 69.14  ? 595 TYR A CB  1 
ATOM 3382 C CG  . TYR A 1 425 ? 148.688 179.783 138.896 1.00 68.65  ? 595 TYR A CG  1 
ATOM 3383 C CD1 . TYR A 1 425 ? 149.490 180.535 139.764 1.00 67.49  ? 595 TYR A CD1 1 
ATOM 3384 C CD2 . TYR A 1 425 ? 147.404 179.435 139.316 1.00 66.99  ? 595 TYR A CD2 1 
ATOM 3385 C CE1 . TYR A 1 425 ? 149.008 180.950 141.008 1.00 66.72  ? 595 TYR A CE1 1 
ATOM 3386 C CE2 . TYR A 1 425 ? 146.918 179.833 140.541 1.00 66.66  ? 595 TYR A CE2 1 
ATOM 3387 C CZ  . TYR A 1 425 ? 147.720 180.582 141.389 1.00 67.79  ? 595 TYR A CZ  1 
ATOM 3388 O OH  . TYR A 1 425 ? 147.203 180.975 142.607 1.00 69.07  ? 595 TYR A OH  1 
ATOM 3389 N N   . THR A 1 426 ? 147.372 180.447 134.817 1.00 70.24  ? 596 THR A N   1 
ATOM 3390 C CA  . THR A 1 426 ? 146.048 180.775 134.306 1.00 70.83  ? 596 THR A CA  1 
ATOM 3391 C C   . THR A 1 426 ? 145.415 179.558 133.667 1.00 70.85  ? 596 THR A C   1 
ATOM 3392 O O   . THR A 1 426 ? 146.049 178.509 133.526 1.00 71.12  ? 596 THR A O   1 
ATOM 3393 C CB  . THR A 1 426 ? 146.093 181.872 133.219 1.00 70.74  ? 596 THR A CB  1 
ATOM 3394 O OG1 . THR A 1 426 ? 146.803 181.369 132.086 1.00 71.14  ? 596 THR A OG1 1 
ATOM 3395 C CG2 . THR A 1 426 ? 146.770 183.139 133.724 1.00 70.52  ? 596 THR A CG2 1 
ATOM 3396 N N   . ALA A 1 427 ? 144.169 179.732 133.245 1.00 70.69  ? 597 ALA A N   1 
ATOM 3397 C CA  . ALA A 1 427 ? 143.402 178.666 132.616 1.00 70.37  ? 597 ALA A CA  1 
ATOM 3398 C C   . ALA A 1 427 ? 144.051 178.035 131.393 1.00 70.44  ? 597 ALA A C   1 
ATOM 3399 O O   . ALA A 1 427 ? 143.715 176.920 131.033 1.00 70.57  ? 597 ALA A O   1 
ATOM 3400 C CB  . ALA A 1 427 ? 142.018 179.148 132.287 1.00 69.81  ? 597 ALA A CB  1 
ATOM 3401 N N   . SER A 1 428 ? 144.992 178.712 130.757 1.00 70.57  ? 598 SER A N   1 
ATOM 3402 C CA  . SER A 1 428 ? 145.599 178.119 129.569 1.00 71.22  ? 598 SER A CA  1 
ATOM 3403 C C   . SER A 1 428 ? 147.088 177.818 129.691 1.00 71.55  ? 598 SER A C   1 
ATOM 3404 O O   . SER A 1 428 ? 147.735 177.433 128.712 1.00 71.74  ? 598 SER A O   1 
ATOM 3405 C CB  . SER A 1 428 ? 145.356 179.026 128.367 1.00 71.17  ? 598 SER A CB  1 
ATOM 3406 O OG  . SER A 1 428 ? 145.776 180.337 128.683 1.00 71.49  ? 598 SER A OG  1 
ATOM 3407 N N   . GLY A 1 429 ? 147.643 177.994 130.877 1.00 71.69  ? 599 GLY A N   1 
ATOM 3408 C CA  . GLY A 1 429 ? 149.063 177.744 131.033 1.00 72.38  ? 599 GLY A CA  1 
ATOM 3409 C C   . GLY A 1 429 ? 149.689 178.654 132.063 1.00 72.83  ? 599 GLY A C   1 
ATOM 3410 O O   . GLY A 1 429 ? 149.034 179.541 132.618 1.00 73.31  ? 599 GLY A O   1 
ATOM 3411 N N   . CYS A 1 430 ? 150.962 178.418 132.328 1.00 72.77  ? 600 CYS A N   1 
ATOM 3412 C CA  . CYS A 1 430 ? 151.678 179.187 133.310 1.00 73.18  ? 600 CYS A CA  1 
ATOM 3413 C C   . CYS A 1 430 ? 152.868 179.879 132.718 1.00 73.05  ? 600 CYS A C   1 
ATOM 3414 O O   . CYS A 1 430 ? 153.364 179.514 131.649 1.00 72.77  ? 600 CYS A O   1 
ATOM 3415 C CB  . CYS A 1 430 ? 152.208 178.255 134.401 1.00 73.03  ? 600 CYS A CB  1 
ATOM 3416 S SG  . CYS A 1 430 ? 150.964 177.184 135.061 1.00 75.62  ? 600 CYS A SG  1 
ATOM 3417 N N   . GLU A 1 431 ? 153.323 180.911 133.446 1.00 73.07  ? 601 GLU A N   1 
ATOM 3418 C CA  . GLU A 1 431 ? 154.520 181.690 133.037 1.00 73.46  ? 601 GLU A CA  1 
ATOM 3419 C C   . GLU A 1 431 ? 155.316 182.014 134.306 1.00 72.71  ? 601 GLU A C   1 
ATOM 3420 O O   . GLU A 1 431 ? 154.756 182.698 135.185 1.00 72.10  ? 601 GLU A O   1 
ATOM 3421 C CB  . GLU A 1 431 ? 154.115 182.963 132.294 1.00 73.65  ? 601 GLU A CB  1 
ATOM 3422 C CG  . GLU A 1 431 ? 155.281 183.898 132.033 1.00 75.07  ? 601 GLU A CG  1 
ATOM 3423 C CD  . GLU A 1 431 ? 154.928 185.144 131.240 1.00 75.79  ? 601 GLU A CD  1 
ATOM 3424 O OE1 . GLU A 1 431 ? 155.756 186.075 131.206 1.00 78.62  ? 601 GLU A OE1 1 
ATOM 3425 O OE2 . GLU A 1 431 ? 153.827 185.179 130.656 1.00 79.44  ? 601 GLU A OE2 1 
ATOM 3426 N N   . VAL A 1 432 ? 156.560 181.545 134.403 1.00 72.15  ? 602 VAL A N   1 
ATOM 3427 C CA  . VAL A 1 432 ? 157.405 181.730 135.559 1.00 71.86  ? 602 VAL A CA  1 
ATOM 3428 C C   . VAL A 1 432 ? 158.449 182.774 135.244 1.00 71.75  ? 602 VAL A C   1 
ATOM 3429 O O   . VAL A 1 432 ? 159.127 182.683 134.228 1.00 72.05  ? 602 VAL A O   1 
ATOM 3430 C CB  . VAL A 1 432 ? 158.098 180.416 135.933 1.00 72.04  ? 602 VAL A CB  1 
ATOM 3431 C CG1 . VAL A 1 432 ? 159.028 180.615 137.109 1.00 70.99  ? 602 VAL A CG1 1 
ATOM 3432 C CG2 . VAL A 1 432 ? 157.051 179.329 136.235 1.00 71.76  ? 602 VAL A CG2 1 
ATOM 3433 N N   . ILE A 1 433 ? 158.569 183.765 136.118 1.00 71.55  ? 603 ILE A N   1 
ATOM 3434 C CA  . ILE A 1 433 ? 159.535 184.831 135.940 1.00 71.21  ? 603 ILE A CA  1 
ATOM 3435 C C   . ILE A 1 433 ? 160.687 184.614 136.892 1.00 70.99  ? 603 ILE A C   1 
ATOM 3436 O O   . ILE A 1 433 ? 160.495 184.464 138.103 1.00 70.48  ? 603 ILE A O   1 
ATOM 3437 C CB  . ILE A 1 433 ? 158.879 186.205 136.117 1.00 71.60  ? 603 ILE A CB  1 
ATOM 3438 C CG1 . ILE A 1 433 ? 157.860 186.409 135.002 1.00 73.26  ? 603 ILE A CG1 1 
ATOM 3439 C CG2 . ILE A 1 433 ? 159.902 187.343 136.014 1.00 70.74  ? 603 ILE A CG2 1 
ATOM 3440 C CD1 . ILE A 1 433 ? 156.554 186.956 135.483 1.00 77.61  ? 603 ILE A CD1 1 
ATOM 3441 N N   . ALA A 1 434 ? 161.892 184.569 136.327 1.00 71.00  ? 604 ALA A N   1 
ATOM 3442 C CA  . ALA A 1 434 ? 163.105 184.348 137.118 1.00 71.06  ? 604 ALA A CA  1 
ATOM 3443 C C   . ALA A 1 434 ? 164.234 185.280 136.724 1.00 71.16  ? 604 ALA A C   1 
ATOM 3444 O O   . ALA A 1 434 ? 164.290 185.784 135.593 1.00 71.31  ? 604 ALA A O   1 
ATOM 3445 C CB  . ALA A 1 434 ? 163.561 182.897 136.995 1.00 70.45  ? 604 ALA A CB  1 
ATOM 3446 N N   . VAL A 1 435 ? 165.148 185.500 137.656 1.00 71.39  ? 605 VAL A N   1 
ATOM 3447 C CA  . VAL A 1 435 ? 166.298 186.356 137.388 1.00 71.69  ? 605 VAL A CA  1 
ATOM 3448 C C   . VAL A 1 435 ? 167.589 185.577 137.549 1.00 72.30  ? 605 VAL A C   1 
ATOM 3449 O O   . VAL A 1 435 ? 167.602 184.500 138.149 1.00 72.33  ? 605 VAL A O   1 
ATOM 3450 C CB  . VAL A 1 435 ? 166.347 187.577 138.333 1.00 71.63  ? 605 VAL A CB  1 
ATOM 3451 C CG1 . VAL A 1 435 ? 165.091 188.430 138.187 1.00 71.02  ? 605 VAL A CG1 1 
ATOM 3452 C CG2 . VAL A 1 435 ? 166.560 187.136 139.769 1.00 70.12  ? 605 VAL A CG2 1 
ATOM 3453 N N   . ASN A 1 436 ? 168.669 186.125 137.008 1.00 73.23  ? 606 ASN A N   1 
ATOM 3454 C CA  . ASN A 1 436 ? 169.989 185.525 137.126 1.00 74.45  ? 606 ASN A CA  1 
ATOM 3455 C C   . ASN A 1 436 ? 170.545 186.040 138.467 1.00 75.31  ? 606 ASN A C   1 
ATOM 3456 O O   . ASN A 1 436 ? 170.669 187.248 138.671 1.00 75.56  ? 606 ASN A O   1 
ATOM 3457 C CB  . ASN A 1 436 ? 170.847 185.944 135.925 1.00 74.24  ? 606 ASN A CB  1 
ATOM 3458 C CG  . ASN A 1 436 ? 172.324 185.539 136.045 1.00 74.38  ? 606 ASN A CG  1 
ATOM 3459 O OD1 . ASN A 1 436 ? 172.721 184.738 136.889 1.00 73.05  ? 606 ASN A OD1 1 
ATOM 3460 N ND2 . ASN A 1 436 ? 173.142 186.112 135.172 1.00 74.80  ? 606 ASN A ND2 1 
ATOM 3461 N N   . THR A 1 437 ? 170.842 185.138 139.394 1.00 76.29  ? 607 THR A N   1 
ATOM 3462 C CA  . THR A 1 437 ? 171.344 185.556 140.711 1.00 77.93  ? 607 THR A CA  1 
ATOM 3463 C C   . THR A 1 437 ? 172.660 186.350 140.707 1.00 79.09  ? 607 THR A C   1 
ATOM 3464 O O   . THR A 1 437 ? 172.943 187.058 141.667 1.00 79.60  ? 607 THR A O   1 
ATOM 3465 C CB  . THR A 1 437 ? 171.501 184.367 141.666 1.00 77.71  ? 607 THR A CB  1 
ATOM 3466 O OG1 . THR A 1 437 ? 172.451 183.453 141.113 1.00 79.09  ? 607 THR A OG1 1 
ATOM 3467 C CG2 . THR A 1 437 ? 170.183 183.649 141.864 1.00 77.26  ? 607 THR A CG2 1 
ATOM 3468 N N   . ARG A 1 438 ? 173.444 186.242 139.635 1.00 80.25  ? 608 ARG A N   1 
ATOM 3469 C CA  . ARG A 1 438 ? 174.728 186.942 139.517 1.00 81.53  ? 608 ARG A CA  1 
ATOM 3470 C C   . ARG A 1 438 ? 174.598 188.396 138.997 1.00 82.30  ? 608 ARG A C   1 
ATOM 3471 O O   . ARG A 1 438 ? 175.524 189.200 139.128 1.00 82.61  ? 608 ARG A O   1 
ATOM 3472 C CB  . ARG A 1 438 ? 175.700 186.113 138.666 1.00 81.68  ? 608 ARG A CB  1 
ATOM 3473 C CG  . ARG A 1 438 ? 176.027 184.731 139.262 1.00 83.01  ? 608 ARG A CG  1 
ATOM 3474 C CD  . ARG A 1 438 ? 176.475 183.729 138.191 1.00 84.96  ? 608 ARG A CD  1 
ATOM 3475 N NE  . ARG A 1 438 ? 175.384 183.380 137.275 1.00 87.43  ? 608 ARG A NE  1 
ATOM 3476 C CZ  . ARG A 1 438 ? 175.496 182.586 136.207 1.00 88.71  ? 608 ARG A CZ  1 
ATOM 3477 N NH1 . ARG A 1 438 ? 176.666 182.037 135.888 1.00 89.61  ? 608 ARG A NH1 1 
ATOM 3478 N NH2 . ARG A 1 438 ? 174.432 182.342 135.444 1.00 87.91  ? 608 ARG A NH2 1 
ATOM 3479 N N   . SER A 1 439 ? 173.452 188.714 138.393 1.00 82.82  ? 609 SER A N   1 
ATOM 3480 C CA  . SER A 1 439 ? 173.126 190.060 137.894 1.00 83.10  ? 609 SER A CA  1 
ATOM 3481 C C   . SER A 1 439 ? 171.604 190.067 137.770 1.00 83.16  ? 609 SER A C   1 
ATOM 3482 O O   . SER A 1 439 ? 171.041 189.649 136.751 1.00 82.93  ? 609 SER A O   1 
ATOM 3483 C CB  . SER A 1 439 ? 173.858 190.444 136.595 1.00 83.18  ? 609 SER A CB  1 
ATOM 3484 O OG  . SER A 1 439 ? 173.295 189.838 135.454 1.00 83.87  ? 609 SER A OG  1 
ATOM 3485 N N   . THR A 1 440 ? 170.959 190.492 138.859 1.00 83.46  ? 610 THR A N   1 
ATOM 3486 C CA  . THR A 1 440 ? 169.486 190.526 138.998 1.00 83.82  ? 610 THR A CA  1 
ATOM 3487 C C   . THR A 1 440 ? 168.667 191.184 137.869 1.00 83.68  ? 610 THR A C   1 
ATOM 3488 O O   . THR A 1 440 ? 167.511 190.803 137.648 1.00 84.04  ? 610 THR A O   1 
ATOM 3489 C CB  . THR A 1 440 ? 169.029 191.076 140.393 1.00 83.83  ? 610 THR A CB  1 
ATOM 3490 O OG1 . THR A 1 440 ? 169.434 192.444 140.526 1.00 85.10  ? 610 THR A OG1 1 
ATOM 3491 C CG2 . THR A 1 440 ? 169.627 190.252 141.533 1.00 83.06  ? 610 THR A CG2 1 
ATOM 3492 N N   . SER A 1 441 ? 169.250 192.143 137.152 1.00 83.04  ? 611 SER A N   1 
ATOM 3493 C CA  . SER A 1 441 ? 168.520 192.790 136.064 1.00 82.63  ? 611 SER A CA  1 
ATOM 3494 C C   . SER A 1 441 ? 168.155 191.803 134.938 1.00 82.25  ? 611 SER A C   1 
ATOM 3495 O O   . SER A 1 441 ? 167.087 191.928 134.325 1.00 82.32  ? 611 SER A O   1 
ATOM 3496 C CB  . SER A 1 441 ? 169.289 193.984 135.518 1.00 82.51  ? 611 SER A CB  1 
ATOM 3497 O OG  . SER A 1 441 ? 170.637 193.632 135.290 1.00 83.76  ? 611 SER A OG  1 
ATOM 3498 N N   . GLN A 1 442 ? 169.027 190.823 134.688 1.00 81.46  ? 612 GLN A N   1 
ATOM 3499 C CA  . GLN A 1 442 ? 168.807 189.808 133.646 1.00 80.69  ? 612 GLN A CA  1 
ATOM 3500 C C   . GLN A 1 442 ? 167.590 188.928 133.969 1.00 79.46  ? 612 GLN A C   1 
ATOM 3501 O O   . GLN A 1 442 ? 167.608 188.157 134.923 1.00 79.31  ? 612 GLN A O   1 
ATOM 3502 C CB  . GLN A 1 442 ? 170.076 188.982 133.450 1.00 81.18  ? 612 GLN A CB  1 
ATOM 3503 C CG  . GLN A 1 442 ? 169.913 187.778 132.538 1.00 83.39  ? 612 GLN A CG  1 
ATOM 3504 C CD  . GLN A 1 442 ? 171.230 187.343 131.901 1.00 86.72  ? 612 GLN A CD  1 
ATOM 3505 O OE1 . GLN A 1 442 ? 172.271 187.247 132.568 1.00 86.55  ? 612 GLN A OE1 1 
ATOM 3506 N NE2 . GLN A 1 442 ? 171.185 187.076 130.594 1.00 87.92  ? 612 GLN A NE2 1 
ATOM 3507 N N   . THR A 1 443 ? 166.540 189.066 133.162 1.00 78.08  ? 613 THR A N   1 
ATOM 3508 C CA  . THR A 1 443 ? 165.287 188.357 133.363 1.00 76.84  ? 613 THR A CA  1 
ATOM 3509 C C   . THR A 1 443 ? 164.955 187.245 132.365 1.00 76.35  ? 613 THR A C   1 
ATOM 3510 O O   . THR A 1 443 ? 165.212 187.370 131.164 1.00 76.39  ? 613 THR A O   1 
ATOM 3511 C CB  . THR A 1 443 ? 164.116 189.371 133.416 1.00 76.66  ? 613 THR A CB  1 
ATOM 3512 O OG1 . THR A 1 443 ? 164.433 190.404 134.347 1.00 76.36  ? 613 THR A OG1 1 
ATOM 3513 C CG2 . THR A 1 443 ? 162.839 188.709 133.889 1.00 76.80  ? 613 THR A CG2 1 
ATOM 3514 N N   . PHE A 1 444 ? 164.346 186.177 132.883 1.00 75.44  ? 614 PHE A N   1 
ATOM 3515 C CA  . PHE A 1 444 ? 163.929 185.031 132.083 1.00 75.09  ? 614 PHE A CA  1 
ATOM 3516 C C   . PHE A 1 444 ? 162.439 184.726 132.262 1.00 74.58  ? 614 PHE A C   1 
ATOM 3517 O O   . PHE A 1 444 ? 161.884 184.839 133.363 1.00 74.71  ? 614 PHE A O   1 
ATOM 3518 C CB  . PHE A 1 444 ? 164.744 183.783 132.440 1.00 75.36  ? 614 PHE A CB  1 
ATOM 3519 C CG  . PHE A 1 444 ? 166.222 183.977 132.333 1.00 76.02  ? 614 PHE A CG  1 
ATOM 3520 C CD1 . PHE A 1 444 ? 166.852 183.971 131.093 1.00 75.27  ? 614 PHE A CD1 1 
ATOM 3521 C CD2 . PHE A 1 444 ? 166.998 184.160 133.479 1.00 77.64  ? 614 PHE A CD2 1 
ATOM 3522 C CE1 . PHE A 1 444 ? 168.228 184.167 130.991 1.00 75.02  ? 614 PHE A CE1 1 
ATOM 3523 C CE2 . PHE A 1 444 ? 168.388 184.355 133.382 1.00 77.15  ? 614 PHE A CE2 1 
ATOM 3524 C CZ  . PHE A 1 444 ? 168.991 184.361 132.131 1.00 75.83  ? 614 PHE A CZ  1 
ATOM 3525 N N   . ILE A 1 445 ? 161.814 184.313 131.172 1.00 73.65  ? 615 ILE A N   1 
ATOM 3526 C CA  . ILE A 1 445 ? 160.406 183.966 131.158 1.00 73.33  ? 615 ILE A CA  1 
ATOM 3527 C C   . ILE A 1 445 ? 160.299 182.510 130.715 1.00 72.88  ? 615 ILE A C   1 
ATOM 3528 O O   . ILE A 1 445 ? 160.882 182.112 129.707 1.00 73.56  ? 615 ILE A O   1 
ATOM 3529 C CB  . ILE A 1 445 ? 159.630 184.845 130.119 1.00 73.30  ? 615 ILE A CB  1 
ATOM 3530 C CG1 . ILE A 1 445 ? 159.735 186.342 130.432 1.00 73.37  ? 615 ILE A CG1 1 
ATOM 3531 C CG2 . ILE A 1 445 ? 158.181 184.431 130.016 1.00 73.76  ? 615 ILE A CG2 1 
ATOM 3532 C CD1 . ILE A 1 445 ? 159.257 186.747 131.793 1.00 75.29  ? 615 ILE A CD1 1 
ATOM 3533 N N   . TYR A 1 446 ? 159.554 181.708 131.448 1.00 71.99  ? 616 TYR A N   1 
ATOM 3534 C CA  . TYR A 1 446 ? 159.389 180.314 131.074 1.00 71.54  ? 616 TYR A CA  1 
ATOM 3535 C C   . TYR A 1 446 ? 157.910 180.001 130.985 1.00 71.33  ? 616 TYR A C   1 
ATOM 3536 O O   . TYR A 1 446 ? 157.191 180.123 131.979 1.00 71.57  ? 616 TYR A O   1 
ATOM 3537 C CB  . TYR A 1 446 ? 160.050 179.399 132.106 1.00 71.24  ? 616 TYR A CB  1 
ATOM 3538 C CG  . TYR A 1 446 ? 161.539 179.594 132.211 1.00 70.96  ? 616 TYR A CG  1 
ATOM 3539 C CD1 . TYR A 1 446 ? 162.080 180.450 133.171 1.00 70.09  ? 616 TYR A CD1 1 
ATOM 3540 C CD2 . TYR A 1 446 ? 162.411 178.935 131.341 1.00 70.29  ? 616 TYR A CD2 1 
ATOM 3541 C CE1 . TYR A 1 446 ? 163.452 180.647 133.262 1.00 70.01  ? 616 TYR A CE1 1 
ATOM 3542 C CE2 . TYR A 1 446 ? 163.785 179.128 131.426 1.00 69.89  ? 616 TYR A CE2 1 
ATOM 3543 C CZ  . TYR A 1 446 ? 164.295 179.987 132.388 1.00 70.17  ? 616 TYR A CZ  1 
ATOM 3544 O OH  . TYR A 1 446 ? 165.650 180.171 132.480 1.00 70.51  ? 616 TYR A OH  1 
ATOM 3545 N N   . LYS A 1 447 ? 157.436 179.626 129.808 1.00 71.06  ? 617 LYS A N   1 
ATOM 3546 C CA  . LYS A 1 447 ? 156.016 179.287 129.673 1.00 71.21  ? 617 LYS A CA  1 
ATOM 3547 C C   . LYS A 1 447 ? 155.876 177.764 129.754 1.00 70.53  ? 617 LYS A C   1 
ATOM 3548 O O   . LYS A 1 447 ? 156.723 177.028 129.224 1.00 71.13  ? 617 LYS A O   1 
ATOM 3549 C CB  . LYS A 1 447 ? 155.423 179.799 128.363 1.00 71.35  ? 617 LYS A CB  1 
ATOM 3550 C CG  . LYS A 1 447 ? 155.877 181.194 127.982 1.00 73.52  ? 617 LYS A CG  1 
ATOM 3551 C CD  . LYS A 1 447 ? 154.920 182.348 128.355 1.00 75.31  ? 617 LYS A CD  1 
ATOM 3552 C CE  . LYS A 1 447 ? 155.404 183.622 127.582 1.00 75.04  ? 617 LYS A CE  1 
ATOM 3553 N NZ  . LYS A 1 447 ? 154.430 184.741 127.461 1.00 75.29  ? 617 LYS A NZ  1 
ATOM 3554 N N   . CYS A 1 448 ? 154.830 177.283 130.416 1.00 68.68  ? 618 CYS A N   1 
ATOM 3555 C CA  . CYS A 1 448 ? 154.643 175.857 130.521 1.00 68.26  ? 618 CYS A CA  1 
ATOM 3556 C C   . CYS A 1 448 ? 153.183 175.526 130.754 1.00 68.05  ? 618 CYS A C   1 
ATOM 3557 O O   . CYS A 1 448 ? 152.362 176.416 130.976 1.00 67.66  ? 618 CYS A O   1 
ATOM 3558 C CB  . CYS A 1 448 ? 155.490 175.313 131.676 1.00 68.73  ? 618 CYS A CB  1 
ATOM 3559 S SG  . CYS A 1 448 ? 155.288 176.263 133.201 1.00 69.34  ? 618 CYS A SG  1 
ATOM 3560 N N   . ASP A 1 449 ? 152.866 174.235 130.709 1.00 68.22  ? 619 ASP A N   1 
ATOM 3561 C CA  . ASP A 1 449 ? 151.505 173.758 130.951 1.00 68.20  ? 619 ASP A CA  1 
ATOM 3562 C C   . ASP A 1 449 ? 151.227 173.654 132.441 1.00 68.30  ? 619 ASP A C   1 
ATOM 3563 O O   . ASP A 1 449 ? 150.083 173.759 132.857 1.00 68.84  ? 619 ASP A O   1 
ATOM 3564 C CB  . ASP A 1 449 ? 151.317 172.369 130.364 1.00 67.94  ? 619 ASP A CB  1 
ATOM 3565 C CG  . ASP A 1 449 ? 151.392 172.358 128.859 1.00 68.55  ? 619 ASP A CG  1 
ATOM 3566 O OD1 . ASP A 1 449 ? 150.459 172.879 128.203 1.00 68.77  ? 619 ASP A OD1 1 
ATOM 3567 O OD2 . ASP A 1 449 ? 152.374 171.808 128.334 1.00 68.95  ? 619 ASP A OD2 1 
ATOM 3568 N N   . ALA A 1 450 ? 152.274 173.414 133.235 1.00 68.26  ? 620 ALA A N   1 
ATOM 3569 C CA  . ALA A 1 450 ? 152.146 173.241 134.693 1.00 67.94  ? 620 ALA A CA  1 
ATOM 3570 C C   . ALA A 1 450 ? 153.434 173.579 135.439 1.00 67.72  ? 620 ALA A C   1 
ATOM 3571 O O   . ALA A 1 450 ? 154.531 173.471 134.889 1.00 67.92  ? 620 ALA A O   1 
ATOM 3572 C CB  . ALA A 1 450 ? 151.733 171.817 135.006 1.00 67.43  ? 620 ALA A CB  1 
ATOM 3573 N N   . VAL A 1 451 ? 153.286 173.996 136.693 1.00 67.72  ? 621 VAL A N   1 
ATOM 3574 C CA  . VAL A 1 451 ? 154.425 174.339 137.540 1.00 67.67  ? 621 VAL A CA  1 
ATOM 3575 C C   . VAL A 1 451 ? 154.426 173.488 138.802 1.00 68.28  ? 621 VAL A C   1 
ATOM 3576 O O   . VAL A 1 451 ? 153.400 173.396 139.515 1.00 68.68  ? 621 VAL A O   1 
ATOM 3577 C CB  . VAL A 1 451 ? 154.407 175.818 138.000 1.00 67.56  ? 621 VAL A CB  1 
ATOM 3578 C CG1 . VAL A 1 451 ? 155.577 176.098 138.969 1.00 66.57  ? 621 VAL A CG1 1 
ATOM 3579 C CG2 . VAL A 1 451 ? 154.465 176.746 136.837 1.00 66.12  ? 621 VAL A CG2 1 
ATOM 3580 N N   . LEU A 1 452 ? 155.579 172.888 139.093 1.00 68.33  ? 622 LEU A N   1 
ATOM 3581 C CA  . LEU A 1 452 ? 155.735 172.105 140.296 1.00 68.32  ? 622 LEU A CA  1 
ATOM 3582 C C   . LEU A 1 452 ? 156.616 172.955 141.201 1.00 68.67  ? 622 LEU A C   1 
ATOM 3583 O O   . LEU A 1 452 ? 157.770 173.219 140.888 1.00 68.77  ? 622 LEU A O   1 
ATOM 3584 C CB  . LEU A 1 452 ? 156.363 170.742 140.024 1.00 68.10  ? 622 LEU A CB  1 
ATOM 3585 C CG  . LEU A 1 452 ? 156.696 169.957 141.309 1.00 68.54  ? 622 LEU A CG  1 
ATOM 3586 C CD1 . LEU A 1 452 ? 155.477 169.772 142.248 1.00 68.64  ? 622 LEU A CD1 1 
ATOM 3587 C CD2 . LEU A 1 452 ? 157.244 168.618 140.953 1.00 68.74  ? 622 LEU A CD2 1 
ATOM 3588 N N   . CYS A 1 453 ? 156.046 173.412 142.307 1.00 69.31  ? 623 CYS A N   1 
ATOM 3589 C CA  . CYS A 1 453 ? 156.756 174.250 143.246 1.00 69.10  ? 623 CYS A CA  1 
ATOM 3590 C C   . CYS A 1 453 ? 157.349 173.439 144.390 1.00 68.79  ? 623 CYS A C   1 
ATOM 3591 O O   . CYS A 1 453 ? 156.613 172.801 145.137 1.00 69.57  ? 623 CYS A O   1 
ATOM 3592 C CB  . CYS A 1 453 ? 155.805 175.305 143.808 1.00 69.22  ? 623 CYS A CB  1 
ATOM 3593 S SG  . CYS A 1 453 ? 156.492 176.187 145.245 1.00 71.45  ? 623 CYS A SG  1 
ATOM 3594 N N   . THR A 1 454 ? 158.672 173.446 144.532 1.00 68.43  ? 624 THR A N   1 
ATOM 3595 C CA  . THR A 1 454 ? 159.294 172.697 145.629 1.00 68.05  ? 624 THR A CA  1 
ATOM 3596 C C   . THR A 1 454 ? 160.059 173.621 146.568 1.00 67.92  ? 624 THR A C   1 
ATOM 3597 O O   . THR A 1 454 ? 160.963 173.195 147.274 1.00 67.66  ? 624 THR A O   1 
ATOM 3598 C CB  . THR A 1 454 ? 160.206 171.525 145.160 1.00 68.01  ? 624 THR A CB  1 
ATOM 3599 O OG1 . THR A 1 454 ? 161.422 172.028 144.609 1.00 66.92  ? 624 THR A OG1 1 
ATOM 3600 C CG2 . THR A 1 454 ? 159.513 170.655 144.151 1.00 67.14  ? 624 THR A CG2 1 
ATOM 3601 N N   . LEU A 1 455 ? 159.681 174.894 146.555 1.00 68.19  ? 625 LEU A N   1 
ATOM 3602 C CA  . LEU A 1 455 ? 160.298 175.908 147.394 1.00 68.20  ? 625 LEU A CA  1 
ATOM 3603 C C   . LEU A 1 455 ? 160.123 175.441 148.826 1.00 68.42  ? 625 LEU A C   1 
ATOM 3604 O O   . LEU A 1 455 ? 159.082 174.888 149.154 1.00 69.21  ? 625 LEU A O   1 
ATOM 3605 C CB  . LEU A 1 455 ? 159.575 177.234 147.212 1.00 67.82  ? 625 LEU A CB  1 
ATOM 3606 C CG  . LEU A 1 455 ? 159.717 177.956 145.876 1.00 67.88  ? 625 LEU A CG  1 
ATOM 3607 C CD1 . LEU A 1 455 ? 158.682 179.083 145.784 1.00 68.38  ? 625 LEU A CD1 1 
ATOM 3608 C CD2 . LEU A 1 455 ? 161.134 178.508 145.681 1.00 64.53  ? 625 LEU A CD2 1 
ATOM 3609 N N   . PRO A 1 456 ? 161.136 175.636 149.681 1.00 68.12  ? 626 PRO A N   1 
ATOM 3610 C CA  . PRO A 1 456 ? 160.971 175.209 151.059 1.00 67.97  ? 626 PRO A CA  1 
ATOM 3611 C C   . PRO A 1 456 ? 159.907 175.995 151.803 1.00 68.46  ? 626 PRO A C   1 
ATOM 3612 O O   . PRO A 1 456 ? 159.626 177.155 151.476 1.00 69.15  ? 626 PRO A O   1 
ATOM 3613 C CB  . PRO A 1 456 ? 162.344 175.510 151.679 1.00 67.82  ? 626 PRO A CB  1 
ATOM 3614 C CG  . PRO A 1 456 ? 163.278 175.574 150.545 1.00 66.92  ? 626 PRO A CG  1 
ATOM 3615 C CD  . PRO A 1 456 ? 162.478 176.193 149.448 1.00 68.15  ? 626 PRO A CD  1 
ATOM 3616 N N   . LEU A 1 457 ? 159.343 175.378 152.831 1.00 68.92  ? 627 LEU A N   1 
ATOM 3617 C CA  . LEU A 1 457 ? 158.340 176.037 153.637 1.00 68.76  ? 627 LEU A CA  1 
ATOM 3618 C C   . LEU A 1 457 ? 158.874 177.378 154.155 1.00 69.32  ? 627 LEU A C   1 
ATOM 3619 O O   . LEU A 1 457 ? 158.138 178.371 154.192 1.00 69.27  ? 627 LEU A O   1 
ATOM 3620 C CB  . LEU A 1 457 ? 157.943 175.143 154.784 1.00 68.44  ? 627 LEU A CB  1 
ATOM 3621 C CG  . LEU A 1 457 ? 156.848 175.714 155.680 1.00 68.30  ? 627 LEU A CG  1 
ATOM 3622 C CD1 . LEU A 1 457 ? 155.548 176.047 154.910 1.00 64.02  ? 627 LEU A CD1 1 
ATOM 3623 C CD2 . LEU A 1 457 ? 156.607 174.755 156.831 1.00 65.78  ? 627 LEU A CD2 1 
ATOM 3624 N N   . GLY A 1 458 ? 160.162 177.410 154.528 1.00 69.28  ? 628 GLY A N   1 
ATOM 3625 C CA  . GLY A 1 458 ? 160.802 178.641 155.014 1.00 68.73  ? 628 GLY A CA  1 
ATOM 3626 C C   . GLY A 1 458 ? 160.677 179.759 153.993 1.00 68.73  ? 628 GLY A C   1 
ATOM 3627 O O   . GLY A 1 458 ? 160.382 180.895 154.349 1.00 67.71  ? 628 GLY A O   1 
ATOM 3628 N N   . VAL A 1 459 ? 160.882 179.420 152.714 1.00 68.93  ? 629 VAL A N   1 
ATOM 3629 C CA  . VAL A 1 459 ? 160.760 180.407 151.645 1.00 68.79  ? 629 VAL A CA  1 
ATOM 3630 C C   . VAL A 1 459 ? 159.284 180.815 151.503 1.00 69.45  ? 629 VAL A C   1 
ATOM 3631 O O   . VAL A 1 459 ? 158.977 182.001 151.471 1.00 69.13  ? 629 VAL A O   1 
ATOM 3632 C CB  . VAL A 1 459 ? 161.359 179.908 150.308 1.00 68.89  ? 629 VAL A CB  1 
ATOM 3633 C CG1 . VAL A 1 459 ? 160.950 180.825 149.148 1.00 66.79  ? 629 VAL A CG1 1 
ATOM 3634 C CG2 . VAL A 1 459 ? 162.881 179.771 150.413 1.00 67.05  ? 629 VAL A CG2 1 
ATOM 3635 N N   . LEU A 1 460 ? 158.371 179.838 151.479 1.00 70.17  ? 630 LEU A N   1 
ATOM 3636 C CA  . LEU A 1 460 ? 156.935 180.137 151.364 1.00 70.80  ? 630 LEU A CA  1 
ATOM 3637 C C   . LEU A 1 460 ? 156.437 181.059 152.473 1.00 71.89  ? 630 LEU A C   1 
ATOM 3638 O O   . LEU A 1 460 ? 155.490 181.806 152.270 1.00 72.41  ? 630 LEU A O   1 
ATOM 3639 C CB  . LEU A 1 460 ? 156.088 178.860 151.318 1.00 70.14  ? 630 LEU A CB  1 
ATOM 3640 C CG  . LEU A 1 460 ? 156.251 177.978 150.067 1.00 69.92  ? 630 LEU A CG  1 
ATOM 3641 C CD1 . LEU A 1 460 ? 155.421 176.720 150.177 1.00 66.77  ? 630 LEU A CD1 1 
ATOM 3642 C CD2 . LEU A 1 460 ? 155.930 178.735 148.763 1.00 66.92  ? 630 LEU A CD2 1 
ATOM 3643 N N   . LYS A 1 461 ? 157.088 181.034 153.629 1.00 73.22  ? 631 LYS A N   1 
ATOM 3644 C CA  . LYS A 1 461 ? 156.690 181.881 154.750 1.00 75.01  ? 631 LYS A CA  1 
ATOM 3645 C C   . LYS A 1 461 ? 157.229 183.305 154.666 1.00 77.38  ? 631 LYS A C   1 
ATOM 3646 O O   . LYS A 1 461 ? 156.706 184.196 155.337 1.00 77.48  ? 631 LYS A O   1 
ATOM 3647 C CB  . LYS A 1 461 ? 157.188 181.296 156.067 1.00 73.86  ? 631 LYS A CB  1 
ATOM 3648 C CG  . LYS A 1 461 ? 156.505 180.041 156.548 1.00 72.66  ? 631 LYS A CG  1 
ATOM 3649 C CD  . LYS A 1 461 ? 157.107 179.680 157.904 1.00 70.19  ? 631 LYS A CD  1 
ATOM 3650 C CE  . LYS A 1 461 ? 156.452 178.497 158.510 1.00 67.13  ? 631 LYS A CE  1 
ATOM 3651 N NZ  . LYS A 1 461 ? 155.225 178.938 159.185 1.00 68.12  ? 631 LYS A NZ  1 
ATOM 3652 N N   . GLN A 1 462 ? 158.298 183.514 153.892 1.00 80.17  ? 632 GLN A N   1 
ATOM 3653 C CA  . GLN A 1 462 ? 158.920 184.836 153.783 1.00 83.45  ? 632 GLN A CA  1 
ATOM 3654 C C   . GLN A 1 462 ? 157.898 185.957 153.641 1.00 84.05  ? 632 GLN A C   1 
ATOM 3655 O O   . GLN A 1 462 ? 157.003 185.911 152.792 1.00 84.53  ? 632 GLN A O   1 
ATOM 3656 C CB  . GLN A 1 462 ? 159.954 184.892 152.649 1.00 82.94  ? 632 GLN A CB  1 
ATOM 3657 C CG  . GLN A 1 462 ? 161.418 184.806 153.086 1.00 85.81  ? 632 GLN A CG  1 
ATOM 3658 C CD  . GLN A 1 462 ? 162.413 185.332 151.994 1.00 87.47  ? 632 GLN A CD  1 
ATOM 3659 O OE1 . GLN A 1 462 ? 163.121 184.536 151.338 1.00 92.78  ? 632 GLN A OE1 1 
ATOM 3660 N NE2 . GLN A 1 462 ? 162.467 186.675 151.809 1.00 89.63  ? 632 GLN A NE2 1 
ATOM 3661 N N   . GLN A 1 463 ? 158.029 186.956 154.500 1.00 85.69  ? 633 GLN A N   1 
ATOM 3662 C CA  . GLN A 1 463 ? 157.145 188.124 154.473 1.00 86.57  ? 633 GLN A CA  1 
ATOM 3663 C C   . GLN A 1 463 ? 158.016 189.389 154.615 1.00 85.89  ? 633 GLN A C   1 
ATOM 3664 O O   . GLN A 1 463 ? 158.775 189.527 155.585 1.00 86.23  ? 633 GLN A O   1 
ATOM 3665 C CB  . GLN A 1 463 ? 156.064 188.025 155.555 1.00 87.23  ? 633 GLN A CB  1 
ATOM 3666 C CG  . GLN A 1 463 ? 154.724 188.673 155.169 1.00 90.40  ? 633 GLN A CG  1 
ATOM 3667 C CD  . GLN A 1 463 ? 153.870 187.814 154.226 1.00 93.68  ? 633 GLN A CD  1 
ATOM 3668 O OE1 . GLN A 1 463 ? 153.285 188.320 153.258 1.00 95.43  ? 633 GLN A OE1 1 
ATOM 3669 N NE2 . GLN A 1 463 ? 153.789 186.519 154.510 1.00 94.07  ? 633 GLN A NE2 1 
ATOM 3670 N N   . PRO A 1 464 ? 157.974 190.281 153.607 1.00 85.40  ? 634 PRO A N   1 
ATOM 3671 C CA  . PRO A 1 464 ? 157.182 190.147 152.381 1.00 84.63  ? 634 PRO A CA  1 
ATOM 3672 C C   . PRO A 1 464 ? 157.757 189.027 151.510 1.00 83.53  ? 634 PRO A C   1 
ATOM 3673 O O   . PRO A 1 464 ? 158.897 188.614 151.727 1.00 83.66  ? 634 PRO A O   1 
ATOM 3674 C CB  . PRO A 1 464 ? 157.343 191.522 151.708 1.00 84.59  ? 634 PRO A CB  1 
ATOM 3675 C CG  . PRO A 1 464 ? 158.647 192.027 152.193 1.00 84.81  ? 634 PRO A CG  1 
ATOM 3676 C CD  . PRO A 1 464 ? 158.788 191.517 153.602 1.00 85.36  ? 634 PRO A CD  1 
ATOM 3677 N N   . PRO A 1 465 ? 156.978 188.532 150.536 1.00 82.54  ? 635 PRO A N   1 
ATOM 3678 C CA  . PRO A 1 465 ? 157.346 187.279 149.873 1.00 81.61  ? 635 PRO A CA  1 
ATOM 3679 C C   . PRO A 1 465 ? 158.611 187.355 149.011 1.00 80.57  ? 635 PRO A C   1 
ATOM 3680 O O   . PRO A 1 465 ? 158.971 188.422 148.526 1.00 80.10  ? 635 PRO A O   1 
ATOM 3681 C CB  . PRO A 1 465 ? 156.127 186.985 148.976 1.00 81.68  ? 635 PRO A CB  1 
ATOM 3682 C CG  . PRO A 1 465 ? 155.036 187.859 149.496 1.00 82.34  ? 635 PRO A CG  1 
ATOM 3683 C CD  . PRO A 1 465 ? 155.731 189.086 149.988 1.00 82.37  ? 635 PRO A CD  1 
ATOM 3684 N N   . ALA A 1 466 ? 159.268 186.214 148.832 1.00 79.31  ? 636 ALA A N   1 
ATOM 3685 C CA  . ALA A 1 466 ? 160.462 186.124 148.005 1.00 77.87  ? 636 ALA A CA  1 
ATOM 3686 C C   . ALA A 1 466 ? 159.983 185.734 146.620 1.00 76.95  ? 636 ALA A C   1 
ATOM 3687 O O   . ALA A 1 466 ? 160.626 186.025 145.623 1.00 77.33  ? 636 ALA A O   1 
ATOM 3688 C CB  . ALA A 1 466 ? 161.383 185.069 148.542 1.00 77.90  ? 636 ALA A CB  1 
ATOM 3689 N N   . VAL A 1 467 ? 158.853 185.036 146.576 1.00 75.49  ? 637 VAL A N   1 
ATOM 3690 C CA  . VAL A 1 467 ? 158.267 184.587 145.332 1.00 73.94  ? 637 VAL A CA  1 
ATOM 3691 C C   . VAL A 1 467 ? 156.810 185.004 145.339 1.00 73.32  ? 637 VAL A C   1 
ATOM 3692 O O   . VAL A 1 467 ? 156.080 184.743 146.281 1.00 73.66  ? 637 VAL A O   1 
ATOM 3693 C CB  . VAL A 1 467 ? 158.413 183.059 145.132 1.00 73.75  ? 637 VAL A CB  1 
ATOM 3694 C CG1 . VAL A 1 467 ? 157.630 182.600 143.904 1.00 72.61  ? 637 VAL A CG1 1 
ATOM 3695 C CG2 . VAL A 1 467 ? 159.888 182.681 144.984 1.00 72.10  ? 637 VAL A CG2 1 
ATOM 3696 N N   . GLN A 1 468 ? 156.393 185.690 144.291 1.00 72.53  ? 638 GLN A N   1 
ATOM 3697 C CA  . GLN A 1 468 ? 155.026 186.148 144.218 1.00 71.37  ? 638 GLN A CA  1 
ATOM 3698 C C   . GLN A 1 468 ? 154.207 185.219 143.338 1.00 70.31  ? 638 GLN A C   1 
ATOM 3699 O O   . GLN A 1 468 ? 154.655 184.816 142.260 1.00 70.42  ? 638 GLN A O   1 
ATOM 3700 C CB  . GLN A 1 468 ? 154.994 187.566 143.677 1.00 71.10  ? 638 GLN A CB  1 
ATOM 3701 C CG  . GLN A 1 468 ? 153.640 188.237 143.775 1.00 72.60  ? 638 GLN A CG  1 
ATOM 3702 C CD  . GLN A 1 468 ? 153.570 189.541 142.979 1.00 73.70  ? 638 GLN A CD  1 
ATOM 3703 O OE1 . GLN A 1 468 ? 154.597 190.165 142.662 1.00 75.66  ? 638 GLN A OE1 1 
ATOM 3704 N NE2 . GLN A 1 468 ? 152.357 189.962 142.664 1.00 72.04  ? 638 GLN A NE2 1 
ATOM 3705 N N   . PHE A 1 469 ? 153.014 184.875 143.807 1.00 68.84  ? 639 PHE A N   1 
ATOM 3706 C CA  . PHE A 1 469 ? 152.116 184.028 143.041 1.00 67.67  ? 639 PHE A CA  1 
ATOM 3707 C C   . PHE A 1 469 ? 151.026 184.907 142.480 1.00 67.41  ? 639 PHE A C   1 
ATOM 3708 O O   . PHE A 1 469 ? 150.448 185.733 143.195 1.00 67.03  ? 639 PHE A O   1 
ATOM 3709 C CB  . PHE A 1 469 ? 151.526 182.924 143.900 1.00 67.07  ? 639 PHE A CB  1 
ATOM 3710 C CG  . PHE A 1 469 ? 152.499 181.870 144.242 1.00 66.11  ? 639 PHE A CG  1 
ATOM 3711 C CD1 . PHE A 1 469 ? 152.685 180.785 143.399 1.00 65.29  ? 639 PHE A CD1 1 
ATOM 3712 C CD2 . PHE A 1 469 ? 153.269 181.967 145.395 1.00 66.09  ? 639 PHE A CD2 1 
ATOM 3713 C CE1 . PHE A 1 469 ? 153.611 179.795 143.712 1.00 65.93  ? 639 PHE A CE1 1 
ATOM 3714 C CE2 . PHE A 1 469 ? 154.211 180.983 145.720 1.00 64.37  ? 639 PHE A CE2 1 
ATOM 3715 C CZ  . PHE A 1 469 ? 154.381 179.902 144.886 1.00 65.68  ? 639 PHE A CZ  1 
ATOM 3716 N N   . VAL A 1 470 ? 150.771 184.755 141.188 1.00 67.20  ? 640 VAL A N   1 
ATOM 3717 C CA  . VAL A 1 470 ? 149.746 185.547 140.534 1.00 67.28  ? 640 VAL A CA  1 
ATOM 3718 C C   . VAL A 1 470 ? 148.792 184.610 139.795 1.00 67.98  ? 640 VAL A C   1 
ATOM 3719 O O   . VAL A 1 470 ? 149.214 183.920 138.859 1.00 68.82  ? 640 VAL A O   1 
ATOM 3720 C CB  . VAL A 1 470 ? 150.366 186.581 139.569 1.00 67.23  ? 640 VAL A CB  1 
ATOM 3721 C CG1 . VAL A 1 470 ? 149.288 187.336 138.823 1.00 66.39  ? 640 VAL A CG1 1 
ATOM 3722 C CG2 . VAL A 1 470 ? 151.260 187.559 140.333 1.00 66.37  ? 640 VAL A CG2 1 
ATOM 3723 N N   . PRO A 1 471 ? 147.510 184.546 140.222 1.00 67.96  ? 641 PRO A N   1 
ATOM 3724 C CA  . PRO A 1 471 ? 146.877 185.211 141.372 1.00 67.80  ? 641 PRO A CA  1 
ATOM 3725 C C   . PRO A 1 471 ? 147.409 184.706 142.718 1.00 68.15  ? 641 PRO A C   1 
ATOM 3726 O O   . PRO A 1 471 ? 148.041 183.633 142.782 1.00 67.69  ? 641 PRO A O   1 
ATOM 3727 C CB  . PRO A 1 471 ? 145.408 184.822 141.226 1.00 67.37  ? 641 PRO A CB  1 
ATOM 3728 C CG  . PRO A 1 471 ? 145.424 183.576 140.455 1.00 67.16  ? 641 PRO A CG  1 
ATOM 3729 C CD  . PRO A 1 471 ? 146.544 183.705 139.494 1.00 67.58  ? 641 PRO A CD  1 
ATOM 3730 N N   . PRO A 1 472 ? 147.162 185.471 143.802 1.00 68.51  ? 642 PRO A N   1 
ATOM 3731 C CA  . PRO A 1 472 ? 147.721 185.024 145.086 1.00 68.43  ? 642 PRO A CA  1 
ATOM 3732 C C   . PRO A 1 472 ? 147.182 183.655 145.436 1.00 69.02  ? 642 PRO A C   1 
ATOM 3733 O O   . PRO A 1 472 ? 146.105 183.279 144.972 1.00 69.42  ? 642 PRO A O   1 
ATOM 3734 C CB  . PRO A 1 472 ? 147.192 186.050 146.095 1.00 68.05  ? 642 PRO A CB  1 
ATOM 3735 C CG  . PRO A 1 472 ? 146.735 187.225 145.293 1.00 67.98  ? 642 PRO A CG  1 
ATOM 3736 C CD  . PRO A 1 472 ? 146.393 186.726 143.919 1.00 67.98  ? 642 PRO A CD  1 
ATOM 3737 N N   . LEU A 1 473 ? 147.919 182.911 146.256 1.00 69.24  ? 643 LEU A N   1 
ATOM 3738 C CA  . LEU A 1 473 ? 147.466 181.604 146.676 1.00 69.10  ? 643 LEU A CA  1 
ATOM 3739 C C   . LEU A 1 473 ? 146.224 181.819 147.555 1.00 68.72  ? 643 LEU A C   1 
ATOM 3740 O O   . LEU A 1 473 ? 146.101 182.856 148.193 1.00 68.77  ? 643 LEU A O   1 
ATOM 3741 C CB  . LEU A 1 473 ? 148.577 180.915 147.463 1.00 69.38  ? 643 LEU A CB  1 
ATOM 3742 C CG  . LEU A 1 473 ? 149.887 180.595 146.737 1.00 69.70  ? 643 LEU A CG  1 
ATOM 3743 C CD1 . LEU A 1 473 ? 150.847 179.857 147.680 1.00 69.08  ? 643 LEU A CD1 1 
ATOM 3744 C CD2 . LEU A 1 473 ? 149.627 179.786 145.475 1.00 68.91  ? 643 LEU A CD2 1 
ATOM 3745 N N   . PRO A 1 474 ? 145.291 180.859 147.581 1.00 68.45  ? 644 PRO A N   1 
ATOM 3746 C CA  . PRO A 1 474 ? 144.103 181.072 148.425 1.00 68.29  ? 644 PRO A CA  1 
ATOM 3747 C C   . PRO A 1 474 ? 144.409 180.977 149.917 1.00 68.89  ? 644 PRO A C   1 
ATOM 3748 O O   . PRO A 1 474 ? 145.462 180.454 150.299 1.00 68.35  ? 644 PRO A O   1 
ATOM 3749 C CB  . PRO A 1 474 ? 143.160 179.940 148.014 1.00 67.79  ? 644 PRO A CB  1 
ATOM 3750 C CG  . PRO A 1 474 ? 143.989 178.942 147.348 1.00 67.92  ? 644 PRO A CG  1 
ATOM 3751 C CD  . PRO A 1 474 ? 145.254 179.581 146.855 1.00 68.16  ? 644 PRO A CD  1 
ATOM 3752 N N   . GLU A 1 475 ? 143.491 181.470 150.747 1.00 69.71  ? 645 GLU A N   1 
ATOM 3753 C CA  . GLU A 1 475 ? 143.670 181.435 152.195 1.00 71.95  ? 645 GLU A CA  1 
ATOM 3754 C C   . GLU A 1 475 ? 143.853 180.047 152.770 1.00 70.63  ? 645 GLU A C   1 
ATOM 3755 O O   . GLU A 1 475 ? 144.621 179.893 153.735 1.00 71.12  ? 645 GLU A O   1 
ATOM 3756 C CB  . GLU A 1 475 ? 142.526 182.123 152.930 1.00 71.53  ? 645 GLU A CB  1 
ATOM 3757 C CG  . GLU A 1 475 ? 142.574 183.647 152.808 1.00 76.89  ? 645 GLU A CG  1 
ATOM 3758 C CD  . GLU A 1 475 ? 141.429 184.344 153.560 1.00 77.67  ? 645 GLU A CD  1 
ATOM 3759 O OE1 . GLU A 1 475 ? 141.123 183.891 154.701 1.00 84.07  ? 645 GLU A OE1 1 
ATOM 3760 O OE2 . GLU A 1 475 ? 140.844 185.326 153.004 1.00 83.38  ? 645 GLU A OE2 1 
ATOM 3761 N N   . TRP A 1 476 ? 143.175 179.041 152.209 1.00 69.09  ? 646 TRP A N   1 
ATOM 3762 C CA  . TRP A 1 476 ? 143.331 177.693 152.757 1.00 68.28  ? 646 TRP A CA  1 
ATOM 3763 C C   . TRP A 1 476 ? 144.788 177.256 152.671 1.00 68.39  ? 646 TRP A C   1 
ATOM 3764 O O   . TRP A 1 476 ? 145.303 176.637 153.588 1.00 69.05  ? 646 TRP A O   1 
ATOM 3765 C CB  . TRP A 1 476 ? 142.336 176.660 152.203 1.00 66.88  ? 646 TRP A CB  1 
ATOM 3766 C CG  . TRP A 1 476 ? 142.412 176.412 150.736 1.00 66.17  ? 646 TRP A CG  1 
ATOM 3767 C CD1 . TRP A 1 476 ? 141.577 176.913 149.791 1.00 64.85  ? 646 TRP A CD1 1 
ATOM 3768 C CD2 . TRP A 1 476 ? 143.360 175.579 150.036 1.00 65.23  ? 646 TRP A CD2 1 
ATOM 3769 N NE1 . TRP A 1 476 ? 141.950 176.470 148.542 1.00 64.34  ? 646 TRP A NE1 1 
ATOM 3770 C CE2 . TRP A 1 476 ? 143.039 175.648 148.662 1.00 64.40  ? 646 TRP A CE2 1 
ATOM 3771 C CE3 . TRP A 1 476 ? 144.451 174.786 150.437 1.00 64.96  ? 646 TRP A CE3 1 
ATOM 3772 C CZ2 . TRP A 1 476 ? 143.765 174.955 147.682 1.00 64.51  ? 646 TRP A CZ2 1 
ATOM 3773 C CZ3 . TRP A 1 476 ? 145.177 174.096 149.458 1.00 64.22  ? 646 TRP A CZ3 1 
ATOM 3774 C CH2 . TRP A 1 476 ? 144.830 174.185 148.105 1.00 65.25  ? 646 TRP A CH2 1 
ATOM 3775 N N   . LYS A 1 477 ? 145.469 177.647 151.608 1.00 68.50  ? 647 LYS A N   1 
ATOM 3776 C CA  . LYS A 1 477 ? 146.874 177.320 151.450 1.00 68.70  ? 647 LYS A CA  1 
ATOM 3777 C C   . LYS A 1 477 ? 147.773 178.228 152.302 1.00 69.13  ? 647 LYS A C   1 
ATOM 3778 O O   . LYS A 1 477 ? 148.641 177.735 153.039 1.00 68.75  ? 647 LYS A O   1 
ATOM 3779 C CB  . LYS A 1 477 ? 147.280 177.431 149.973 1.00 68.53  ? 647 LYS A CB  1 
ATOM 3780 C CG  . LYS A 1 477 ? 148.773 177.274 149.691 1.00 68.27  ? 647 LYS A CG  1 
ATOM 3781 C CD  . LYS A 1 477 ? 149.200 175.821 149.655 1.00 68.89  ? 647 LYS A CD  1 
ATOM 3782 C CE  . LYS A 1 477 ? 148.541 175.061 148.496 1.00 69.98  ? 647 LYS A CE  1 
ATOM 3783 N NZ  . LYS A 1 477 ? 148.942 173.609 148.426 1.00 69.82  ? 647 LYS A NZ  1 
ATOM 3784 N N   . THR A 1 478 ? 147.589 179.547 152.195 1.00 69.44  ? 648 THR A N   1 
ATOM 3785 C CA  . THR A 1 478 ? 148.454 180.472 152.958 1.00 70.05  ? 648 THR A CA  1 
ATOM 3786 C C   . THR A 1 478 ? 148.395 180.257 154.462 1.00 70.44  ? 648 THR A C   1 
ATOM 3787 O O   . THR A 1 478 ? 149.428 180.350 155.123 1.00 70.64  ? 648 THR A O   1 
ATOM 3788 C CB  . THR A 1 478 ? 148.276 181.970 152.589 1.00 69.53  ? 648 THR A CB  1 
ATOM 3789 O OG1 . THR A 1 478 ? 146.939 182.372 152.875 1.00 71.91  ? 648 THR A OG1 1 
ATOM 3790 C CG2 . THR A 1 478 ? 148.568 182.214 151.118 1.00 68.48  ? 648 THR A CG2 1 
ATOM 3791 N N   . SER A 1 479 ? 147.205 179.932 154.979 1.00 70.89  ? 649 SER A N   1 
ATOM 3792 C CA  . SER A 1 479 ? 146.993 179.644 156.410 1.00 71.60  ? 649 SER A CA  1 
ATOM 3793 C C   . SER A 1 479 ? 147.725 178.381 156.823 1.00 71.88  ? 649 SER A C   1 
ATOM 3794 O O   . SER A 1 479 ? 148.221 178.298 157.944 1.00 72.72  ? 649 SER A O   1 
ATOM 3795 C CB  . SER A 1 479 ? 145.520 179.448 156.732 1.00 71.34  ? 649 SER A CB  1 
ATOM 3796 O OG  . SER A 1 479 ? 144.839 180.676 156.630 1.00 73.00  ? 649 SER A OG  1 
ATOM 3797 N N   . ALA A 1 480 ? 147.781 177.392 155.934 1.00 71.91  ? 650 ALA A N   1 
ATOM 3798 C CA  . ALA A 1 480 ? 148.492 176.166 156.239 1.00 71.77  ? 650 ALA A CA  1 
ATOM 3799 C C   . ALA A 1 480 ? 149.937 176.572 156.348 1.00 72.14  ? 650 ALA A C   1 
ATOM 3800 O O   . ALA A 1 480 ? 150.599 176.198 157.305 1.00 72.88  ? 650 ALA A O   1 
ATOM 3801 C CB  . ALA A 1 480 ? 148.326 175.162 155.158 1.00 71.86  ? 650 ALA A CB  1 
ATOM 3802 N N   . VAL A 1 481 ? 150.409 177.378 155.402 1.00 72.13  ? 651 VAL A N   1 
ATOM 3803 C CA  . VAL A 1 481 ? 151.788 177.849 155.412 1.00 72.87  ? 651 VAL A CA  1 
ATOM 3804 C C   . VAL A 1 481 ? 152.115 178.607 156.705 1.00 74.01  ? 651 VAL A C   1 
ATOM 3805 O O   . VAL A 1 481 ? 153.172 178.392 157.288 1.00 74.16  ? 651 VAL A O   1 
ATOM 3806 C CB  . VAL A 1 481 ? 152.125 178.711 154.150 1.00 72.86  ? 651 VAL A CB  1 
ATOM 3807 C CG1 . VAL A 1 481 ? 153.453 179.468 154.298 1.00 71.11  ? 651 VAL A CG1 1 
ATOM 3808 C CG2 . VAL A 1 481 ? 152.160 177.844 152.925 1.00 72.73  ? 651 VAL A CG2 1 
ATOM 3809 N N   . GLN A 1 482 ? 151.203 179.457 157.163 1.00 74.98  ? 652 GLN A N   1 
ATOM 3810 C CA  . GLN A 1 482 ? 151.421 180.220 158.389 1.00 76.86  ? 652 GLN A CA  1 
ATOM 3811 C C   . GLN A 1 482 ? 151.451 179.338 159.639 1.00 76.10  ? 652 GLN A C   1 
ATOM 3812 O O   . GLN A 1 482 ? 152.268 179.543 160.537 1.00 75.82  ? 652 GLN A O   1 
ATOM 3813 C CB  . GLN A 1 482 ? 150.359 181.310 158.539 1.00 76.36  ? 652 GLN A CB  1 
ATOM 3814 C CG  . GLN A 1 482 ? 150.725 182.630 157.881 1.00 80.54  ? 652 GLN A CG  1 
ATOM 3815 C CD  . GLN A 1 482 ? 149.525 183.337 157.283 1.00 81.59  ? 652 GLN A CD  1 
ATOM 3816 O OE1 . GLN A 1 482 ? 148.380 183.039 157.624 1.00 87.91  ? 652 GLN A OE1 1 
ATOM 3817 N NE2 . GLN A 1 482 ? 149.780 184.280 156.384 1.00 85.50  ? 652 GLN A NE2 1 
ATOM 3818 N N   . ARG A 1 483 ? 150.552 178.360 159.688 1.00 75.77  ? 653 ARG A N   1 
ATOM 3819 C CA  . ARG A 1 483 ? 150.449 177.449 160.808 1.00 75.29  ? 653 ARG A CA  1 
ATOM 3820 C C   . ARG A 1 483 ? 151.626 176.496 160.998 1.00 76.17  ? 653 ARG A C   1 
ATOM 3821 O O   . ARG A 1 483 ? 152.094 176.343 162.116 1.00 75.94  ? 653 ARG A O   1 
ATOM 3822 C CB  . ARG A 1 483 ? 149.163 176.631 160.712 1.00 74.96  ? 653 ARG A CB  1 
ATOM 3823 C CG  . ARG A 1 483 ? 147.926 177.365 161.132 1.00 73.33  ? 653 ARG A CG  1 
ATOM 3824 C CD  . ARG A 1 483 ? 146.785 176.401 161.385 1.00 71.44  ? 653 ARG A CD  1 
ATOM 3825 N NE  . ARG A 1 483 ? 146.449 175.582 160.225 1.00 69.92  ? 653 ARG A NE  1 
ATOM 3826 C CZ  . ARG A 1 483 ? 145.672 175.991 159.225 1.00 69.09  ? 653 ARG A CZ  1 
ATOM 3827 N NH1 . ARG A 1 483 ? 145.168 177.211 159.248 1.00 69.53  ? 653 ARG A NH1 1 
ATOM 3828 N NH2 . ARG A 1 483 ? 145.399 175.190 158.201 1.00 66.60  ? 653 ARG A NH2 1 
ATOM 3829 N N   . MET A 1 484 ? 152.080 175.839 159.927 1.00 76.82  ? 654 MET A N   1 
ATOM 3830 C CA  . MET A 1 484 ? 153.182 174.878 160.017 1.00 78.74  ? 654 MET A CA  1 
ATOM 3831 C C   . MET A 1 484 ? 154.446 175.477 160.611 1.00 76.81  ? 654 MET A C   1 
ATOM 3832 O O   . MET A 1 484 ? 154.709 176.670 160.470 1.00 77.59  ? 654 MET A O   1 
ATOM 3833 C CB  . MET A 1 484 ? 153.521 174.288 158.659 1.00 77.29  ? 654 MET A CB  1 
ATOM 3834 C CG  . MET A 1 484 ? 152.347 173.612 157.980 1.00 82.74  ? 654 MET A CG  1 
ATOM 3835 S SD  . MET A 1 484 ? 152.787 172.533 156.562 1.00 86.70  ? 654 MET A SD  1 
ATOM 3836 C CE  . MET A 1 484 ? 154.387 171.924 157.158 1.00 85.79  ? 654 MET A CE  1 
ATOM 3837 N N   . GLY A 1 485 ? 155.231 174.644 161.273 1.00 75.07  ? 655 GLY A N   1 
ATOM 3838 C CA  . GLY A 1 485 ? 156.455 175.123 161.828 1.00 73.66  ? 655 GLY A CA  1 
ATOM 3839 C C   . GLY A 1 485 ? 157.600 174.916 160.854 1.00 72.61  ? 655 GLY A C   1 
ATOM 3840 O O   . GLY A 1 485 ? 157.591 173.958 160.071 1.00 72.82  ? 655 GLY A O   1 
ATOM 3841 N N   . PHE A 1 486 ? 158.576 175.821 160.885 1.00 70.75  ? 656 PHE A N   1 
ATOM 3842 C CA  . PHE A 1 486 ? 159.761 175.673 160.057 1.00 69.66  ? 656 PHE A CA  1 
ATOM 3843 C C   . PHE A 1 486 ? 160.955 175.914 160.972 1.00 69.72  ? 656 PHE A C   1 
ATOM 3844 O O   . PHE A 1 486 ? 161.275 177.053 161.362 1.00 69.56  ? 656 PHE A O   1 
ATOM 3845 C CB  . PHE A 1 486 ? 159.793 176.538 158.800 1.00 68.70  ? 656 PHE A CB  1 
ATOM 3846 C CG  . PHE A 1 486 ? 160.784 176.037 157.773 1.00 67.75  ? 656 PHE A CG  1 
ATOM 3847 C CD1 . PHE A 1 486 ? 160.612 174.782 157.175 1.00 66.87  ? 656 PHE A CD1 1 
ATOM 3848 C CD2 . PHE A 1 486 ? 161.907 176.778 157.437 1.00 65.16  ? 656 PHE A CD2 1 
ATOM 3849 C CE1 . PHE A 1 486 ? 161.525 174.292 156.237 1.00 65.29  ? 656 PHE A CE1 1 
ATOM 3850 C CE2 . PHE A 1 486 ? 162.821 176.297 156.492 1.00 64.77  ? 656 PHE A CE2 1 
ATOM 3851 C CZ  . PHE A 1 486 ? 162.633 175.049 155.902 1.00 65.83  ? 656 PHE A CZ  1 
ATOM 3852 N N   . GLY A 1 487 ? 161.574 174.803 161.347 1.00 69.32  ? 657 GLY A N   1 
ATOM 3853 C CA  . GLY A 1 487 ? 162.688 174.820 162.270 1.00 69.41  ? 657 GLY A CA  1 
ATOM 3854 C C   . GLY A 1 487 ? 164.042 175.222 161.756 1.00 69.45  ? 657 GLY A C   1 
ATOM 3855 O O   . GLY A 1 487 ? 164.200 175.729 160.626 1.00 69.79  ? 657 GLY A O   1 
ATOM 3856 N N   . ASN A 1 488 ? 165.020 174.959 162.607 1.00 69.06  ? 658 ASN A N   1 
ATOM 3857 C CA  . ASN A 1 488 ? 166.401 175.301 162.359 1.00 69.23  ? 658 ASN A CA  1 
ATOM 3858 C C   . ASN A 1 488 ? 167.330 174.479 163.252 1.00 69.36  ? 658 ASN A C   1 
ATOM 3859 O O   . ASN A 1 488 ? 166.983 174.173 164.392 1.00 69.73  ? 658 ASN A O   1 
ATOM 3860 C CB  . ASN A 1 488 ? 166.575 176.778 162.704 1.00 68.84  ? 658 ASN A CB  1 
ATOM 3861 C CG  . ASN A 1 488 ? 167.926 177.326 162.316 1.00 69.31  ? 658 ASN A CG  1 
ATOM 3862 O OD1 . ASN A 1 488 ? 168.561 176.842 161.383 1.00 69.56  ? 658 ASN A OD1 1 
ATOM 3863 N ND2 . ASN A 1 488 ? 168.360 178.373 163.014 1.00 69.25  ? 658 ASN A ND2 1 
ATOM 3864 N N   . LEU A 1 489 ? 168.496 174.140 162.708 1.00 69.34  ? 659 LEU A N   1 
ATOM 3865 C CA  . LEU A 1 489 ? 169.562 173.426 163.385 1.00 69.44  ? 659 LEU A CA  1 
ATOM 3866 C C   . LEU A 1 489 ? 170.833 173.678 162.582 1.00 69.04  ? 659 LEU A C   1 
ATOM 3867 O O   . LEU A 1 489 ? 170.772 173.807 161.369 1.00 68.67  ? 659 LEU A O   1 
ATOM 3868 C CB  . LEU A 1 489 ? 169.252 171.940 163.553 1.00 69.73  ? 659 LEU A CB  1 
ATOM 3869 C CG  . LEU A 1 489 ? 169.378 170.878 162.471 1.00 70.70  ? 659 LEU A CG  1 
ATOM 3870 C CD1 . LEU A 1 489 ? 170.788 170.414 162.396 1.00 72.50  ? 659 LEU A CD1 1 
ATOM 3871 C CD2 . LEU A 1 489 ? 168.540 169.682 162.879 1.00 70.43  ? 659 LEU A CD2 1 
ATOM 3872 N N   . ASN A 1 490 ? 171.977 173.801 163.246 1.00 69.00  ? 660 ASN A N   1 
ATOM 3873 C CA  . ASN A 1 490 ? 173.219 174.066 162.515 1.00 69.00  ? 660 ASN A CA  1 
ATOM 3874 C C   . ASN A 1 490 ? 174.360 173.130 162.857 1.00 68.97  ? 660 ASN A C   1 
ATOM 3875 O O   . ASN A 1 490 ? 174.303 172.404 163.850 1.00 68.94  ? 660 ASN A O   1 
ATOM 3876 C CB  . ASN A 1 490 ? 173.633 175.532 162.604 1.00 68.45  ? 660 ASN A CB  1 
ATOM 3877 C CG  . ASN A 1 490 ? 172.782 176.426 161.710 1.00 69.81  ? 660 ASN A CG  1 
ATOM 3878 O OD1 . ASN A 1 490 ? 172.776 176.297 160.476 1.00 70.34  ? 660 ASN A OD1 1 
ATOM 3879 N ND2 . ASN A 1 490 ? 172.049 177.340 162.334 1.00 70.16  ? 660 ASN A ND2 1 
ATOM 3880 N N   . LYS A 1 491 ? 175.375 173.118 162.000 1.00 68.69  ? 661 LYS A N   1 
ATOM 3881 C CA  . LYS A 1 491 ? 176.504 172.246 162.198 1.00 68.63  ? 661 LYS A CA  1 
ATOM 3882 C C   . LYS A 1 491 ? 177.767 173.045 162.046 1.00 69.16  ? 661 LYS A C   1 
ATOM 3883 O O   . LYS A 1 491 ? 177.825 173.984 161.232 1.00 69.82  ? 661 LYS A O   1 
ATOM 3884 C CB  . LYS A 1 491 ? 176.491 171.116 161.170 1.00 68.34  ? 661 LYS A CB  1 
ATOM 3885 C CG  . LYS A 1 491 ? 175.120 170.498 160.979 1.00 68.98  ? 661 LYS A CG  1 
ATOM 3886 C CD  . LYS A 1 491 ? 175.166 169.216 160.211 1.00 68.85  ? 661 LYS A CD  1 
ATOM 3887 C CE  . LYS A 1 491 ? 173.811 168.566 160.226 1.00 68.28  ? 661 LYS A CE  1 
ATOM 3888 N NZ  . LYS A 1 491 ? 173.943 167.198 159.693 1.00 70.90  ? 661 LYS A NZ  1 
ATOM 3889 N N   . VAL A 1 492 ? 178.769 172.658 162.831 1.00 68.76  ? 662 VAL A N   1 
ATOM 3890 C CA  . VAL A 1 492 ? 180.076 173.262 162.824 1.00 68.75  ? 662 VAL A CA  1 
ATOM 3891 C C   . VAL A 1 492 ? 181.032 172.132 162.459 1.00 69.16  ? 662 VAL A C   1 
ATOM 3892 O O   . VAL A 1 492 ? 181.175 171.157 163.212 1.00 69.36  ? 662 VAL A O   1 
ATOM 3893 C CB  . VAL A 1 492 ? 180.456 173.807 164.225 1.00 68.85  ? 662 VAL A CB  1 
ATOM 3894 C CG1 . VAL A 1 492 ? 181.797 174.513 164.175 1.00 67.40  ? 662 VAL A CG1 1 
ATOM 3895 C CG2 . VAL A 1 492 ? 179.382 174.742 164.750 1.00 68.66  ? 662 VAL A CG2 1 
ATOM 3896 N N   . VAL A 1 493 ? 181.676 172.257 161.304 1.00 69.24  ? 663 VAL A N   1 
ATOM 3897 C CA  . VAL A 1 493 ? 182.616 171.249 160.830 1.00 69.42  ? 663 VAL A CA  1 
ATOM 3898 C C   . VAL A 1 493 ? 184.035 171.626 161.242 1.00 69.84  ? 663 VAL A C   1 
ATOM 3899 O O   . VAL A 1 493 ? 184.526 172.703 160.899 1.00 69.93  ? 663 VAL A O   1 
ATOM 3900 C CB  . VAL A 1 493 ? 182.538 171.075 159.295 1.00 69.54  ? 663 VAL A CB  1 
ATOM 3901 C CG1 . VAL A 1 493 ? 183.576 170.069 158.815 1.00 69.54  ? 663 VAL A CG1 1 
ATOM 3902 C CG2 . VAL A 1 493 ? 181.145 170.642 158.875 1.00 68.97  ? 663 VAL A CG2 1 
ATOM 3903 N N   . LEU A 1 494 ? 184.685 170.729 161.979 1.00 70.11  ? 664 LEU A N   1 
ATOM 3904 C CA  . LEU A 1 494 ? 186.044 170.942 162.449 1.00 70.46  ? 664 LEU A CA  1 
ATOM 3905 C C   . LEU A 1 494 ? 186.987 169.923 161.817 1.00 70.84  ? 664 LEU A C   1 
ATOM 3906 O O   . LEU A 1 494 ? 186.936 168.725 162.134 1.00 70.85  ? 664 LEU A O   1 
ATOM 3907 C CB  . LEU A 1 494 ? 186.111 170.867 163.981 1.00 70.34  ? 664 LEU A CB  1 
ATOM 3908 C CG  . LEU A 1 494 ? 185.139 171.761 164.760 1.00 70.46  ? 664 LEU A CG  1 
ATOM 3909 C CD1 . LEU A 1 494 ? 185.009 171.284 166.193 1.00 70.45  ? 664 LEU A CD1 1 
ATOM 3910 C CD2 . LEU A 1 494 ? 185.546 173.232 164.722 1.00 69.91  ? 664 LEU A CD2 1 
ATOM 3911 N N   . CYS A 1 495 ? 187.840 170.411 160.921 1.00 71.08  ? 665 CYS A N   1 
ATOM 3912 C CA  . CYS A 1 495 ? 188.804 169.571 160.229 1.00 71.58  ? 665 CYS A CA  1 
ATOM 3913 C C   . CYS A 1 495 ? 190.169 169.614 160.902 1.00 71.92  ? 665 CYS A C   1 
ATOM 3914 O O   . CYS A 1 495 ? 190.819 170.656 160.950 1.00 72.12  ? 665 CYS A O   1 
ATOM 3915 C CB  . CYS A 1 495 ? 188.921 169.992 158.772 1.00 71.44  ? 665 CYS A CB  1 
ATOM 3916 S SG  . CYS A 1 495 ? 187.395 169.780 157.872 1.00 71.76  ? 665 CYS A SG  1 
ATOM 3917 N N   . PHE A 1 496 ? 190.598 168.474 161.424 1.00 72.26  ? 666 PHE A N   1 
ATOM 3918 C CA  . PHE A 1 496 ? 191.884 168.404 162.095 1.00 72.70  ? 666 PHE A CA  1 
ATOM 3919 C C   . PHE A 1 496 ? 192.910 167.632 161.282 1.00 73.19  ? 666 PHE A C   1 
ATOM 3920 O O   . PHE A 1 496 ? 192.568 166.979 160.291 1.00 73.19  ? 666 PHE A O   1 
ATOM 3921 C CB  . PHE A 1 496 ? 191.724 167.798 163.492 1.00 72.44  ? 666 PHE A CB  1 
ATOM 3922 C CG  . PHE A 1 496 ? 190.841 168.601 164.397 1.00 72.09  ? 666 PHE A CG  1 
ATOM 3923 C CD1 . PHE A 1 496 ? 191.312 169.768 164.993 1.00 71.71  ? 666 PHE A CD1 1 
ATOM 3924 C CD2 . PHE A 1 496 ? 189.534 168.200 164.647 1.00 71.35  ? 666 PHE A CD2 1 
ATOM 3925 C CE1 . PHE A 1 496 ? 190.495 170.522 165.828 1.00 71.60  ? 666 PHE A CE1 1 
ATOM 3926 C CE2 . PHE A 1 496 ? 188.711 168.941 165.483 1.00 71.19  ? 666 PHE A CE2 1 
ATOM 3927 C CZ  . PHE A 1 496 ? 189.191 170.107 166.077 1.00 71.63  ? 666 PHE A CZ  1 
ATOM 3928 N N   . ASP A 1 497 ? 194.170 167.733 161.702 1.00 73.65  ? 667 ASP A N   1 
ATOM 3929 C CA  . ASP A 1 497 ? 195.260 167.048 161.031 1.00 74.13  ? 667 ASP A CA  1 
ATOM 3930 C C   . ASP A 1 497 ? 195.634 165.762 161.783 1.00 74.23  ? 667 ASP A C   1 
ATOM 3931 O O   . ASP A 1 497 ? 196.537 165.033 161.363 1.00 74.34  ? 667 ASP A O   1 
ATOM 3932 C CB  . ASP A 1 497 ? 196.465 167.985 160.884 1.00 74.31  ? 667 ASP A CB  1 
ATOM 3933 C CG  . ASP A 1 497 ? 197.124 168.322 162.220 1.00 75.57  ? 667 ASP A CG  1 
ATOM 3934 O OD1 . ASP A 1 497 ? 196.407 168.492 163.230 1.00 77.38  ? 667 ASP A OD1 1 
ATOM 3935 O OD2 . ASP A 1 497 ? 198.369 168.424 162.261 1.00 76.32  ? 667 ASP A OD2 1 
ATOM 3936 N N   . ARG A 1 498 ? 194.923 165.497 162.885 1.00 74.20  ? 668 ARG A N   1 
ATOM 3937 C CA  . ARG A 1 498 ? 195.149 164.312 163.733 1.00 74.28  ? 668 ARG A CA  1 
ATOM 3938 C C   . ARG A 1 498 ? 193.913 163.918 164.568 1.00 73.83  ? 668 ARG A C   1 
ATOM 3939 O O   . ARG A 1 498 ? 193.011 164.721 164.781 1.00 73.75  ? 668 ARG A O   1 
ATOM 3940 C CB  . ARG A 1 498 ? 196.374 164.513 164.635 1.00 74.10  ? 668 ARG A CB  1 
ATOM 3941 C CG  . ARG A 1 498 ? 196.430 165.857 165.355 1.00 74.67  ? 668 ARG A CG  1 
ATOM 3942 C CD  . ARG A 1 498 ? 197.811 166.114 165.980 1.00 75.47  ? 668 ARG A CD  1 
ATOM 3943 N NE  . ARG A 1 498 ? 197.723 167.104 167.057 1.00 78.09  ? 668 ARG A NE  1 
ATOM 3944 C CZ  . ARG A 1 498 ? 198.713 167.445 167.881 1.00 78.93  ? 668 ARG A CZ  1 
ATOM 3945 N NH1 . ARG A 1 498 ? 199.912 166.879 167.778 1.00 79.89  ? 668 ARG A NH1 1 
ATOM 3946 N NH2 . ARG A 1 498 ? 198.497 168.358 168.824 1.00 79.03  ? 668 ARG A NH2 1 
ATOM 3947 N N   . VAL A 1 499 ? 193.884 162.672 165.032 1.00 73.49  ? 669 VAL A N   1 
ATOM 3948 C CA  . VAL A 1 499 ? 192.772 162.159 165.830 1.00 72.84  ? 669 VAL A CA  1 
ATOM 3949 C C   . VAL A 1 499 ? 193.139 162.173 167.317 1.00 72.77  ? 669 VAL A C   1 
ATOM 3950 O O   . VAL A 1 499 ? 193.958 161.367 167.769 1.00 72.85  ? 669 VAL A O   1 
ATOM 3951 C CB  . VAL A 1 499 ? 192.391 160.711 165.399 1.00 72.73  ? 669 VAL A CB  1 
ATOM 3952 C CG1 . VAL A 1 499 ? 191.250 160.158 166.251 1.00 72.38  ? 669 VAL A CG1 1 
ATOM 3953 C CG2 . VAL A 1 499 ? 192.038 160.657 163.925 1.00 72.10  ? 669 VAL A CG2 1 
ATOM 3954 N N   . PHE A 1 500 ? 192.534 163.090 168.073 1.00 72.49  ? 670 PHE A N   1 
ATOM 3955 C CA  . PHE A 1 500 ? 192.791 163.197 169.520 1.00 71.90  ? 670 PHE A CA  1 
ATOM 3956 C C   . PHE A 1 500 ? 191.637 162.617 170.339 1.00 71.85  ? 670 PHE A C   1 
ATOM 3957 O O   . PHE A 1 500 ? 191.707 162.547 171.561 1.00 71.72  ? 670 PHE A O   1 
ATOM 3958 C CB  . PHE A 1 500 ? 193.058 164.652 169.929 1.00 71.58  ? 670 PHE A CB  1 
ATOM 3959 C CG  . PHE A 1 500 ? 191.944 165.599 169.576 1.00 71.40  ? 670 PHE A CG  1 
ATOM 3960 C CD1 . PHE A 1 500 ? 190.837 165.742 170.410 1.00 70.96  ? 670 PHE A CD1 1 
ATOM 3961 C CD2 . PHE A 1 500 ? 192.000 166.353 168.407 1.00 71.30  ? 670 PHE A CD2 1 
ATOM 3962 C CE1 . PHE A 1 500 ? 189.805 166.617 170.082 1.00 70.77  ? 670 PHE A CE1 1 
ATOM 3963 C CE2 . PHE A 1 500 ? 190.970 167.231 168.071 1.00 70.35  ? 670 PHE A CE2 1 
ATOM 3964 C CZ  . PHE A 1 500 ? 189.874 167.361 168.909 1.00 70.43  ? 670 PHE A CZ  1 
ATOM 3965 N N   . TRP A 1 501 ? 190.573 162.212 169.652 1.00 71.83  ? 671 TRP A N   1 
ATOM 3966 C CA  . TRP A 1 501 ? 189.400 161.641 170.298 1.00 71.95  ? 671 TRP A CA  1 
ATOM 3967 C C   . TRP A 1 501 ? 189.373 160.120 170.185 1.00 72.49  ? 671 TRP A C   1 
ATOM 3968 O O   . TRP A 1 501 ? 190.199 159.521 169.504 1.00 72.34  ? 671 TRP A O   1 
ATOM 3969 C CB  . TRP A 1 501 ? 188.126 162.226 169.679 1.00 71.56  ? 671 TRP A CB  1 
ATOM 3970 C CG  . TRP A 1 501 ? 188.051 162.047 168.194 1.00 70.59  ? 671 TRP A CG  1 
ATOM 3971 C CD1 . TRP A 1 501 ? 187.513 160.988 167.523 1.00 70.00  ? 671 TRP A CD1 1 
ATOM 3972 C CD2 . TRP A 1 501 ? 188.548 162.945 167.197 1.00 70.15  ? 671 TRP A CD2 1 
ATOM 3973 N NE1 . TRP A 1 501 ? 187.640 161.173 166.168 1.00 69.93  ? 671 TRP A NE1 1 
ATOM 3974 C CE2 . TRP A 1 501 ? 188.272 162.367 165.940 1.00 70.03  ? 671 TRP A CE2 1 
ATOM 3975 C CE3 . TRP A 1 501 ? 189.202 164.181 167.243 1.00 70.29  ? 671 TRP A CE3 1 
ATOM 3976 C CZ2 . TRP A 1 501 ? 188.626 162.985 164.734 1.00 70.30  ? 671 TRP A CZ2 1 
ATOM 3977 C CZ3 . TRP A 1 501 ? 189.549 164.799 166.038 1.00 70.59  ? 671 TRP A CZ3 1 
ATOM 3978 C CH2 . TRP A 1 501 ? 189.258 164.198 164.803 1.00 70.00  ? 671 TRP A CH2 1 
ATOM 3979 N N   . ASP A 1 502 ? 188.389 159.515 170.840 1.00 73.43  ? 672 ASP A N   1 
ATOM 3980 C CA  . ASP A 1 502 ? 188.209 158.074 170.824 1.00 74.35  ? 672 ASP A CA  1 
ATOM 3981 C C   . ASP A 1 502 ? 187.653 157.645 169.463 1.00 75.09  ? 672 ASP A C   1 
ATOM 3982 O O   . ASP A 1 502 ? 186.517 158.008 169.097 1.00 75.41  ? 672 ASP A O   1 
ATOM 3983 C CB  . ASP A 1 502 ? 187.251 157.679 171.938 1.00 74.61  ? 672 ASP A CB  1 
ATOM 3984 C CG  . ASP A 1 502 ? 187.377 156.231 172.328 1.00 75.09  ? 672 ASP A CG  1 
ATOM 3985 O OD1 . ASP A 1 502 ? 187.580 155.391 171.417 1.00 75.65  ? 672 ASP A OD1 1 
ATOM 3986 O OD2 . ASP A 1 502 ? 187.260 155.941 173.544 1.00 75.20  ? 672 ASP A OD2 1 
ATOM 3987 N N   . PRO A 1 503 ? 188.450 156.880 168.697 1.00 75.54  ? 673 PRO A N   1 
ATOM 3988 C CA  . PRO A 1 503 ? 188.066 156.559 167.314 1.00 75.74  ? 673 PRO A CA  1 
ATOM 3989 C C   . PRO A 1 503 ? 186.952 155.516 167.226 1.00 76.11  ? 673 PRO A C   1 
ATOM 3990 O O   . PRO A 1 503 ? 186.303 155.394 166.192 1.00 76.22  ? 673 PRO A O   1 
ATOM 3991 C CB  . PRO A 1 503 ? 189.361 156.010 166.694 1.00 75.62  ? 673 PRO A CB  1 
ATOM 3992 C CG  . PRO A 1 503 ? 190.440 156.199 167.748 1.00 75.79  ? 673 PRO A CG  1 
ATOM 3993 C CD  . PRO A 1 503 ? 189.736 156.272 169.065 1.00 75.39  ? 673 PRO A CD  1 
ATOM 3994 N N   . SER A 1 504 ? 186.736 154.770 168.304 1.00 76.69  ? 674 SER A N   1 
ATOM 3995 C CA  . SER A 1 504 ? 185.698 153.745 168.319 1.00 77.05  ? 674 SER A CA  1 
ATOM 3996 C C   . SER A 1 504 ? 184.355 154.337 168.740 1.00 77.14  ? 674 SER A C   1 
ATOM 3997 O O   . SER A 1 504 ? 183.330 153.649 168.735 1.00 77.37  ? 674 SER A O   1 
ATOM 3998 C CB  . SER A 1 504 ? 186.101 152.583 169.226 1.00 76.95  ? 674 SER A CB  1 
ATOM 3999 O OG  . SER A 1 504 ? 186.227 153.026 170.559 1.00 77.38  ? 674 SER A OG  1 
ATOM 4000 N N   . VAL A 1 505 ? 184.373 155.621 169.090 1.00 77.19  ? 675 VAL A N   1 
ATOM 4001 C CA  . VAL A 1 505 ? 183.170 156.339 169.502 1.00 77.22  ? 675 VAL A CA  1 
ATOM 4002 C C   . VAL A 1 505 ? 182.679 157.241 168.361 1.00 77.18  ? 675 VAL A C   1 
ATOM 4003 O O   . VAL A 1 505 ? 183.394 158.151 167.947 1.00 77.48  ? 675 VAL A O   1 
ATOM 4004 C CB  . VAL A 1 505 ? 183.441 157.175 170.774 1.00 77.26  ? 675 VAL A CB  1 
ATOM 4005 C CG1 . VAL A 1 505 ? 182.270 158.093 171.073 1.00 77.47  ? 675 VAL A CG1 1 
ATOM 4006 C CG2 . VAL A 1 505 ? 183.715 156.262 171.964 1.00 76.87  ? 675 VAL A CG2 1 
ATOM 4007 N N   . ASN A 1 506 ? 181.473 156.984 167.852 1.00 76.98  ? 676 ASN A N   1 
ATOM 4008 C CA  . ASN A 1 506 ? 180.905 157.782 166.752 1.00 77.10  ? 676 ASN A CA  1 
ATOM 4009 C C   . ASN A 1 506 ? 180.385 159.142 167.159 1.00 76.60  ? 676 ASN A C   1 
ATOM 4010 O O   . ASN A 1 506 ? 180.321 160.066 166.334 1.00 76.49  ? 676 ASN A O   1 
ATOM 4011 C CB  . ASN A 1 506 ? 179.732 157.057 166.082 1.00 77.37  ? 676 ASN A CB  1 
ATOM 4012 C CG  . ASN A 1 506 ? 180.164 156.140 164.966 1.00 79.28  ? 676 ASN A CG  1 
ATOM 4013 O OD1 . ASN A 1 506 ? 179.446 155.197 164.616 1.00 81.88  ? 676 ASN A OD1 1 
ATOM 4014 N ND2 . ASN A 1 506 ? 181.338 156.401 164.396 1.00 80.75  ? 676 ASN A ND2 1 
ATOM 4015 N N   . LEU A 1 507 ? 179.958 159.254 168.414 1.00 75.83  ? 677 LEU A N   1 
ATOM 4016 C CA  . LEU A 1 507 ? 179.387 160.503 168.893 1.00 75.30  ? 677 LEU A CA  1 
ATOM 4017 C C   . LEU A 1 507 ? 179.507 160.673 170.388 1.00 74.18  ? 677 LEU A C   1 
ATOM 4018 O O   . LEU A 1 507 ? 179.534 159.696 171.124 1.00 74.84  ? 677 LEU A O   1 
ATOM 4019 C CB  . LEU A 1 507 ? 177.912 160.611 168.446 1.00 75.77  ? 677 LEU A CB  1 
ATOM 4020 C CG  . LEU A 1 507 ? 176.791 159.651 168.907 1.00 76.82  ? 677 LEU A CG  1 
ATOM 4021 C CD1 . LEU A 1 507 ? 175.473 160.072 168.304 1.00 77.62  ? 677 LEU A CD1 1 
ATOM 4022 C CD2 . LEU A 1 507 ? 177.018 158.208 168.535 1.00 77.83  ? 677 LEU A CD2 1 
ATOM 4023 N N   . PHE A 1 508 ? 179.604 161.919 170.833 1.00 72.68  ? 678 PHE A N   1 
ATOM 4024 C CA  . PHE A 1 508 ? 179.695 162.216 172.267 1.00 71.14  ? 678 PHE A CA  1 
ATOM 4025 C C   . PHE A 1 508 ? 179.036 163.548 172.571 1.00 71.01  ? 678 PHE A C   1 
ATOM 4026 O O   . PHE A 1 508 ? 178.949 164.421 171.700 1.00 70.93  ? 678 PHE A O   1 
ATOM 4027 C CB  . PHE A 1 508 ? 181.123 162.121 172.821 1.00 70.15  ? 678 PHE A CB  1 
ATOM 4028 C CG  . PHE A 1 508 ? 182.101 163.068 172.198 1.00 68.01  ? 678 PHE A CG  1 
ATOM 4029 C CD1 . PHE A 1 508 ? 182.847 162.683 171.090 1.00 66.89  ? 678 PHE A CD1 1 
ATOM 4030 C CD2 . PHE A 1 508 ? 182.314 164.327 172.745 1.00 66.21  ? 678 PHE A CD2 1 
ATOM 4031 C CE1 . PHE A 1 508 ? 183.772 163.545 170.517 1.00 66.35  ? 678 PHE A CE1 1 
ATOM 4032 C CE2 . PHE A 1 508 ? 183.240 165.200 172.187 1.00 65.82  ? 678 PHE A CE2 1 
ATOM 4033 C CZ  . PHE A 1 508 ? 183.971 164.808 171.072 1.00 67.26  ? 678 PHE A CZ  1 
ATOM 4034 N N   . GLY A 1 509 ? 178.548 163.701 173.795 1.00 70.70  ? 679 GLY A N   1 
ATOM 4035 C CA  . GLY A 1 509 ? 177.861 164.926 174.147 1.00 70.48  ? 679 GLY A CA  1 
ATOM 4036 C C   . GLY A 1 509 ? 178.541 165.869 175.095 1.00 70.24  ? 679 GLY A C   1 
ATOM 4037 O O   . GLY A 1 509 ? 179.401 165.466 175.868 1.00 70.64  ? 679 GLY A O   1 
ATOM 4038 N N   . HIS A 1 510 ? 178.142 167.135 175.020 1.00 69.93  ? 680 HIS A N   1 
ATOM 4039 C CA  . HIS A 1 510 ? 178.645 168.170 175.901 1.00 69.81  ? 680 HIS A CA  1 
ATOM 4040 C C   . HIS A 1 510 ? 177.417 168.679 176.626 1.00 69.96  ? 680 HIS A C   1 
ATOM 4041 O O   . HIS A 1 510 ? 176.469 169.145 175.989 1.00 69.80  ? 680 HIS A O   1 
ATOM 4042 C CB  . HIS A 1 510 ? 179.314 169.313 175.149 1.00 69.57  ? 680 HIS A CB  1 
ATOM 4043 C CG  . HIS A 1 510 ? 179.387 170.581 175.943 1.00 69.56  ? 680 HIS A CG  1 
ATOM 4044 N ND1 . HIS A 1 510 ? 178.617 171.688 175.652 1.00 70.20  ? 680 HIS A ND1 1 
ATOM 4045 C CD2 . HIS A 1 510 ? 180.113 170.907 177.041 1.00 69.60  ? 680 HIS A CD2 1 
ATOM 4046 C CE1 . HIS A 1 510 ? 178.878 172.646 176.525 1.00 69.95  ? 680 HIS A CE1 1 
ATOM 4047 N NE2 . HIS A 1 510 ? 179.785 172.200 177.374 1.00 69.26  ? 680 HIS A NE2 1 
ATOM 4048 N N   . VAL A 1 511 ? 177.423 168.566 177.951 1.00 70.12  ? 681 VAL A N   1 
ATOM 4049 C CA  . VAL A 1 511 ? 176.296 169.009 178.765 1.00 70.20  ? 681 VAL A CA  1 
ATOM 4050 C C   . VAL A 1 511 ? 176.487 170.472 179.127 1.00 70.61  ? 681 VAL A C   1 
ATOM 4051 O O   . VAL A 1 511 ? 177.472 170.824 179.759 1.00 71.30  ? 681 VAL A O   1 
ATOM 4052 C CB  . VAL A 1 511 ? 176.135 168.133 180.014 1.00 69.94  ? 681 VAL A CB  1 
ATOM 4053 C CG1 . VAL A 1 511 ? 174.979 168.612 180.866 1.00 69.30  ? 681 VAL A CG1 1 
ATOM 4054 C CG2 . VAL A 1 511 ? 175.916 166.691 179.599 1.00 70.03  ? 681 VAL A CG2 1 
ATOM 4055 N N   . GLY A 1 512 ? 175.553 171.316 178.700 1.00 71.23  ? 682 GLY A N   1 
ATOM 4056 C CA  . GLY A 1 512 ? 175.601 172.752 178.951 1.00 72.06  ? 682 GLY A CA  1 
ATOM 4057 C C   . GLY A 1 512 ? 175.405 173.107 180.412 1.00 72.93  ? 682 GLY A C   1 
ATOM 4058 O O   . GLY A 1 512 ? 174.965 172.279 181.207 1.00 73.48  ? 682 GLY A O   1 
ATOM 4059 N N   . SER A 1 513 ? 175.742 174.345 180.771 1.00 73.15  ? 683 SER A N   1 
ATOM 4060 C CA  . SER A 1 513 ? 175.600 174.815 182.140 1.00 73.37  ? 683 SER A CA  1 
ATOM 4061 C C   . SER A 1 513 ? 174.181 175.222 182.512 1.00 73.00  ? 683 SER A C   1 
ATOM 4062 O O   . SER A 1 513 ? 173.759 175.050 183.661 1.00 73.29  ? 683 SER A O   1 
ATOM 4063 C CB  . SER A 1 513 ? 176.518 176.002 182.363 1.00 73.56  ? 683 SER A CB  1 
ATOM 4064 O OG  . SER A 1 513 ? 177.863 175.576 182.324 1.00 76.08  ? 683 SER A OG  1 
ATOM 4065 N N   . THR A 1 514 ? 173.463 175.791 181.549 1.00 72.42  ? 684 THR A N   1 
ATOM 4066 C CA  . THR A 1 514 ? 172.105 176.259 181.767 1.00 71.85  ? 684 THR A CA  1 
ATOM 4067 C C   . THR A 1 514 ? 171.131 175.692 180.738 1.00 71.44  ? 684 THR A C   1 
ATOM 4068 O O   . THR A 1 514 ? 171.541 175.212 179.672 1.00 71.40  ? 684 THR A O   1 
ATOM 4069 C CB  . THR A 1 514 ? 172.034 177.792 181.641 1.00 72.03  ? 684 THR A CB  1 
ATOM 4070 O OG1 . THR A 1 514 ? 172.300 178.164 180.280 1.00 72.52  ? 684 THR A OG1 1 
ATOM 4071 C CG2 . THR A 1 514 ? 173.036 178.473 182.558 1.00 71.16  ? 684 THR A CG2 1 
ATOM 4072 N N   . THR A 1 515 ? 169.843 175.790 181.061 1.00 70.40  ? 685 THR A N   1 
ATOM 4073 C CA  . THR A 1 515 ? 168.771 175.340 180.202 1.00 69.66  ? 685 THR A CA  1 
ATOM 4074 C C   . THR A 1 515 ? 168.778 176.162 178.908 1.00 69.41  ? 685 THR A C   1 
ATOM 4075 O O   . THR A 1 515 ? 168.666 175.615 177.809 1.00 69.68  ? 685 THR A O   1 
ATOM 4076 C CB  . THR A 1 515 ? 167.418 175.524 180.909 1.00 69.84  ? 685 THR A CB  1 
ATOM 4077 O OG1 . THR A 1 515 ? 167.397 174.747 182.111 1.00 69.11  ? 685 THR A OG1 1 
ATOM 4078 C CG2 . THR A 1 515 ? 166.252 175.116 180.010 1.00 68.97  ? 685 THR A CG2 1 
ATOM 4079 N N   . ALA A 1 516 ? 168.934 177.473 179.059 1.00 68.91  ? 686 ALA A N   1 
ATOM 4080 C CA  . ALA A 1 516 ? 168.969 178.412 177.950 1.00 68.12  ? 686 ALA A CA  1 
ATOM 4081 C C   . ALA A 1 516 ? 169.934 177.990 176.869 1.00 67.98  ? 686 ALA A C   1 
ATOM 4082 O O   . ALA A 1 516 ? 169.606 178.073 175.689 1.00 68.66  ? 686 ALA A O   1 
ATOM 4083 C CB  . ALA A 1 516 ? 169.329 179.799 178.446 1.00 68.09  ? 686 ALA A CB  1 
ATOM 4084 N N   . SER A 1 517 ? 171.115 177.538 177.267 1.00 67.47  ? 687 SER A N   1 
ATOM 4085 C CA  . SER A 1 517 ? 172.134 177.130 176.316 1.00 67.15  ? 687 SER A CA  1 
ATOM 4086 C C   . SER A 1 517 ? 172.264 175.615 176.088 1.00 66.59  ? 687 SER A C   1 
ATOM 4087 O O   . SER A 1 517 ? 173.266 175.161 175.539 1.00 66.61  ? 687 SER A O   1 
ATOM 4088 C CB  . SER A 1 517 ? 173.482 177.700 176.757 1.00 67.16  ? 687 SER A CB  1 
ATOM 4089 O OG  . SER A 1 517 ? 174.000 176.921 177.821 1.00 68.46  ? 687 SER A OG  1 
ATOM 4090 N N   . ARG A 1 518 ? 171.269 174.830 176.484 1.00 66.34  ? 688 ARG A N   1 
ATOM 4091 C CA  . ARG A 1 518 ? 171.336 173.373 176.302 1.00 66.35  ? 688 ARG A CA  1 
ATOM 4092 C C   . ARG A 1 518 ? 171.676 172.898 174.880 1.00 66.93  ? 688 ARG A C   1 
ATOM 4093 O O   . ARG A 1 518 ? 172.392 171.922 174.710 1.00 67.16  ? 688 ARG A O   1 
ATOM 4094 C CB  . ARG A 1 518 ? 170.055 172.691 176.796 1.00 66.23  ? 688 ARG A CB  1 
ATOM 4095 C CG  . ARG A 1 518 ? 168.793 172.968 175.980 1.00 65.08  ? 688 ARG A CG  1 
ATOM 4096 C CD  . ARG A 1 518 ? 167.566 172.539 176.768 1.00 64.32  ? 688 ARG A CD  1 
ATOM 4097 N NE  . ARG A 1 518 ? 166.285 172.647 176.050 1.00 62.28  ? 688 ARG A NE  1 
ATOM 4098 C CZ  . ARG A 1 518 ? 165.104 172.508 176.651 1.00 61.39  ? 688 ARG A CZ  1 
ATOM 4099 N NH1 . ARG A 1 518 ? 165.044 172.256 177.969 1.00 62.82  ? 688 ARG A NH1 1 
ATOM 4100 N NH2 . ARG A 1 518 ? 163.989 172.612 175.960 1.00 57.52  ? 688 ARG A NH2 1 
ATOM 4101 N N   . GLY A 1 519 ? 171.171 173.581 173.859 1.00 67.49  ? 689 GLY A N   1 
ATOM 4102 C CA  . GLY A 1 519 ? 171.449 173.168 172.486 1.00 67.75  ? 689 GLY A CA  1 
ATOM 4103 C C   . GLY A 1 519 ? 172.765 173.638 171.891 1.00 68.01  ? 689 GLY A C   1 
ATOM 4104 O O   . GLY A 1 519 ? 173.096 173.254 170.770 1.00 68.27  ? 689 GLY A O   1 
ATOM 4105 N N   . GLU A 1 520 ? 173.509 174.465 172.622 1.00 67.75  ? 690 GLU A N   1 
ATOM 4106 C CA  . GLU A 1 520 ? 174.768 174.999 172.117 1.00 68.35  ? 690 GLU A CA  1 
ATOM 4107 C C   . GLU A 1 520 ? 175.922 174.009 172.086 1.00 67.99  ? 690 GLU A C   1 
ATOM 4108 O O   . GLU A 1 520 ? 176.534 173.722 173.116 1.00 68.56  ? 690 GLU A O   1 
ATOM 4109 C CB  . GLU A 1 520 ? 175.173 176.261 172.892 1.00 68.34  ? 690 GLU A CB  1 
ATOM 4110 C CG  . GLU A 1 520 ? 176.578 176.764 172.585 1.00 69.12  ? 690 GLU A CG  1 
ATOM 4111 C CD  . GLU A 1 520 ? 176.897 178.089 173.259 1.00 69.86  ? 690 GLU A CD  1 
ATOM 4112 O OE1 . GLU A 1 520 ? 176.153 179.071 173.041 1.00 73.06  ? 690 GLU A OE1 1 
ATOM 4113 O OE2 . GLU A 1 520 ? 177.903 178.162 173.998 1.00 73.12  ? 690 GLU A OE2 1 
ATOM 4114 N N   . LEU A 1 521 ? 176.236 173.506 170.900 1.00 67.77  ? 691 LEU A N   1 
ATOM 4115 C CA  . LEU A 1 521 ? 177.343 172.565 170.730 1.00 67.41  ? 691 LEU A CA  1 
ATOM 4116 C C   . LEU A 1 521 ? 177.217 171.403 171.715 1.00 67.68  ? 691 LEU A C   1 
ATOM 4117 O O   . LEU A 1 521 ? 178.198 170.993 172.353 1.00 67.77  ? 691 LEU A O   1 
ATOM 4118 C CB  . LEU A 1 521 ? 178.680 173.303 170.905 1.00 66.79  ? 691 LEU A CB  1 
ATOM 4119 C CG  . LEU A 1 521 ? 178.835 174.573 170.058 1.00 65.96  ? 691 LEU A CG  1 
ATOM 4120 C CD1 . LEU A 1 521 ? 179.979 175.419 170.542 1.00 64.11  ? 691 LEU A CD1 1 
ATOM 4121 C CD2 . LEU A 1 521 ? 178.993 174.249 168.568 1.00 64.15  ? 691 LEU A CD2 1 
ATOM 4122 N N   . PHE A 1 522 ? 175.997 170.889 171.835 1.00 67.43  ? 692 PHE A N   1 
ATOM 4123 C CA  . PHE A 1 522 ? 175.710 169.811 172.759 1.00 67.61  ? 692 PHE A CA  1 
ATOM 4124 C C   . PHE A 1 522 ? 176.155 168.434 172.287 1.00 68.16  ? 692 PHE A C   1 
ATOM 4125 O O   . PHE A 1 522 ? 176.259 167.522 173.093 1.00 68.76  ? 692 PHE A O   1 
ATOM 4126 C CB  . PHE A 1 522 ? 174.213 169.771 173.047 1.00 67.06  ? 692 PHE A CB  1 
ATOM 4127 C CG  . PHE A 1 522 ? 173.421 169.049 171.993 1.00 67.31  ? 692 PHE A CG  1 
ATOM 4128 C CD1 . PHE A 1 522 ? 173.178 169.640 170.754 1.00 66.24  ? 692 PHE A CD1 1 
ATOM 4129 C CD2 . PHE A 1 522 ? 172.934 167.767 172.229 1.00 66.62  ? 692 PHE A CD2 1 
ATOM 4130 C CE1 . PHE A 1 522 ? 172.461 168.967 169.790 1.00 66.58  ? 692 PHE A CE1 1 
ATOM 4131 C CE2 . PHE A 1 522 ? 172.211 167.085 171.262 1.00 65.82  ? 692 PHE A CE2 1 
ATOM 4132 C CZ  . PHE A 1 522 ? 171.974 167.679 170.045 1.00 66.33  ? 692 PHE A CZ  1 
ATOM 4133 N N   . LEU A 1 523 ? 176.380 168.261 170.989 1.00 68.79  ? 693 LEU A N   1 
ATOM 4134 C CA  . LEU A 1 523 ? 176.772 166.950 170.460 1.00 68.87  ? 693 LEU A CA  1 
ATOM 4135 C C   . LEU A 1 523 ? 177.863 167.035 169.401 1.00 69.30  ? 693 LEU A C   1 
ATOM 4136 O O   . LEU A 1 523 ? 177.857 167.939 168.564 1.00 69.40  ? 693 LEU A O   1 
ATOM 4137 C CB  . LEU A 1 523 ? 175.537 166.278 169.874 1.00 68.54  ? 693 LEU A CB  1 
ATOM 4138 C CG  . LEU A 1 523 ? 175.639 164.930 169.181 1.00 67.93  ? 693 LEU A CG  1 
ATOM 4139 C CD1 . LEU A 1 523 ? 176.096 163.858 170.138 1.00 67.48  ? 693 LEU A CD1 1 
ATOM 4140 C CD2 . LEU A 1 523 ? 174.288 164.584 168.629 1.00 67.63  ? 693 LEU A CD2 1 
ATOM 4141 N N   . PHE A 1 524 ? 178.782 166.080 169.431 1.00 69.93  ? 694 PHE A N   1 
ATOM 4142 C CA  . PHE A 1 524 ? 179.892 166.039 168.486 1.00 70.88  ? 694 PHE A CA  1 
ATOM 4143 C C   . PHE A 1 524 ? 179.920 164.721 167.741 1.00 71.97  ? 694 PHE A C   1 
ATOM 4144 O O   . PHE A 1 524 ? 179.831 163.664 168.368 1.00 72.29  ? 694 PHE A O   1 
ATOM 4145 C CB  . PHE A 1 524 ? 181.219 166.204 169.228 1.00 70.52  ? 694 PHE A CB  1 
ATOM 4146 C CG  . PHE A 1 524 ? 181.453 167.585 169.753 1.00 69.95  ? 694 PHE A CG  1 
ATOM 4147 C CD1 . PHE A 1 524 ? 180.830 168.020 170.911 1.00 69.95  ? 694 PHE A CD1 1 
ATOM 4148 C CD2 . PHE A 1 524 ? 182.317 168.447 169.100 1.00 70.03  ? 694 PHE A CD2 1 
ATOM 4149 C CE1 . PHE A 1 524 ? 181.048 169.305 171.405 1.00 70.09  ? 694 PHE A CE1 1 
ATOM 4150 C CE2 . PHE A 1 524 ? 182.544 169.731 169.580 1.00 70.11  ? 694 PHE A CE2 1 
ATOM 4151 C CZ  . PHE A 1 524 ? 181.907 170.159 170.740 1.00 70.13  ? 694 PHE A CZ  1 
ATOM 4152 N N   . TRP A 1 525 ? 180.061 164.775 166.416 1.00 73.15  ? 695 TRP A N   1 
ATOM 4153 C CA  . TRP A 1 525 ? 180.122 163.561 165.604 1.00 74.21  ? 695 TRP A CA  1 
ATOM 4154 C C   . TRP A 1 525 ? 181.520 163.294 165.047 1.00 74.07  ? 695 TRP A C   1 
ATOM 4155 O O   . TRP A 1 525 ? 182.209 164.204 164.590 1.00 73.81  ? 695 TRP A O   1 
ATOM 4156 C CB  . TRP A 1 525 ? 179.181 163.634 164.412 1.00 75.44  ? 695 TRP A CB  1 
ATOM 4157 C CG  . TRP A 1 525 ? 177.714 163.715 164.675 1.00 77.12  ? 695 TRP A CG  1 
ATOM 4158 C CD1 . TRP A 1 525 ? 176.995 164.841 164.942 1.00 80.03  ? 695 TRP A CD1 1 
ATOM 4159 C CD2 . TRP A 1 525 ? 176.757 162.646 164.590 1.00 78.79  ? 695 TRP A CD2 1 
ATOM 4160 N NE1 . TRP A 1 525 ? 175.655 164.545 165.061 1.00 80.11  ? 695 TRP A NE1 1 
ATOM 4161 C CE2 . TRP A 1 525 ? 175.479 163.205 164.852 1.00 79.84  ? 695 TRP A CE2 1 
ATOM 4162 C CE3 . TRP A 1 525 ? 176.856 161.270 164.334 1.00 79.37  ? 695 TRP A CE3 1 
ATOM 4163 C CZ2 . TRP A 1 525 ? 174.300 162.436 164.868 1.00 79.85  ? 695 TRP A CZ2 1 
ATOM 4164 C CZ3 . TRP A 1 525 ? 175.679 160.496 164.345 1.00 79.73  ? 695 TRP A CZ3 1 
ATOM 4165 C CH2 . TRP A 1 525 ? 174.417 161.088 164.614 1.00 79.47  ? 695 TRP A CH2 1 
ATOM 4166 N N   . ASN A 1 526 ? 181.903 162.022 165.069 1.00 74.08  ? 696 ASN A N   1 
ATOM 4167 C CA  . ASN A 1 526 ? 183.168 161.543 164.540 1.00 74.44  ? 696 ASN A CA  1 
ATOM 4168 C C   . ASN A 1 526 ? 182.679 160.638 163.439 1.00 74.75  ? 696 ASN A C   1 
ATOM 4169 O O   . ASN A 1 526 ? 182.238 159.527 163.725 1.00 74.71  ? 696 ASN A O   1 
ATOM 4170 C CB  . ASN A 1 526 ? 183.924 160.740 165.608 1.00 74.32  ? 696 ASN A CB  1 
ATOM 4171 C CG  . ASN A 1 526 ? 184.992 159.833 165.014 1.00 74.40  ? 696 ASN A CG  1 
ATOM 4172 O OD1 . ASN A 1 526 ? 185.555 160.119 163.948 1.00 75.52  ? 696 ASN A OD1 1 
ATOM 4173 N ND2 . ASN A 1 526 ? 185.265 158.728 165.689 1.00 73.11  ? 696 ASN A ND2 1 
ATOM 4174 N N   . LEU A 1 527 ? 182.700 161.091 162.186 1.00 75.60  ? 697 LEU A N   1 
ATOM 4175 C CA  . LEU A 1 527 ? 182.127 160.240 161.145 1.00 76.45  ? 697 LEU A CA  1 
ATOM 4176 C C   . LEU A 1 527 ? 182.756 159.964 159.794 1.00 77.13  ? 697 LEU A C   1 
ATOM 4177 O O   . LEU A 1 527 ? 182.218 159.123 159.042 1.00 77.79  ? 697 LEU A O   1 
ATOM 4178 C CB  . LEU A 1 527 ? 180.721 160.755 160.834 1.00 76.35  ? 697 LEU A CB  1 
ATOM 4179 C CG  . LEU A 1 527 ? 179.599 160.502 161.825 1.00 76.84  ? 697 LEU A CG  1 
ATOM 4180 C CD1 . LEU A 1 527 ? 178.457 161.414 161.450 1.00 78.50  ? 697 LEU A CD1 1 
ATOM 4181 C CD2 . LEU A 1 527 ? 179.188 159.044 161.779 1.00 77.32  ? 697 LEU A CD2 1 
ATOM 4182 N N   . TYR A 1 528 ? 183.810 160.664 159.405 1.00 77.13  ? 698 TYR A N   1 
ATOM 4183 C CA  . TYR A 1 528 ? 184.284 160.395 158.051 1.00 77.10  ? 698 TYR A CA  1 
ATOM 4184 C C   . TYR A 1 528 ? 185.662 159.763 157.935 1.00 77.07  ? 698 TYR A C   1 
ATOM 4185 O O   . TYR A 1 528 ? 186.259 159.412 158.948 1.00 77.15  ? 698 TYR A O   1 
ATOM 4186 C CB  . TYR A 1 528 ? 184.100 161.646 157.178 1.00 77.09  ? 698 TYR A CB  1 
ATOM 4187 C CG  . TYR A 1 528 ? 182.666 162.179 157.154 1.00 77.15  ? 698 TYR A CG  1 
ATOM 4188 C CD1 . TYR A 1 528 ? 182.200 163.073 158.136 1.00 76.75  ? 698 TYR A CD1 1 
ATOM 4189 C CD2 . TYR A 1 528 ? 181.772 161.801 156.134 1.00 77.62  ? 698 TYR A CD2 1 
ATOM 4190 C CE1 . TYR A 1 528 ? 180.878 163.565 158.108 1.00 76.30  ? 698 TYR A CE1 1 
ATOM 4191 C CE2 . TYR A 1 528 ? 180.451 162.291 156.096 1.00 76.31  ? 698 TYR A CE2 1 
ATOM 4192 C CZ  . TYR A 1 528 ? 180.015 163.171 157.080 1.00 76.85  ? 698 TYR A CZ  1 
ATOM 4193 O OH  . TYR A 1 528 ? 178.720 163.646 157.030 1.00 77.53  ? 698 TYR A OH  1 
ATOM 4194 N N   . LYS A 1 529 ? 186.130 159.587 156.695 1.00 77.08  ? 699 LYS A N   1 
ATOM 4195 C CA  . LYS A 1 529 ? 187.446 158.987 156.429 1.00 77.49  ? 699 LYS A CA  1 
ATOM 4196 C C   . LYS A 1 529 ? 188.546 159.848 157.058 1.00 76.87  ? 699 LYS A C   1 
ATOM 4197 O O   . LYS A 1 529 ? 189.456 159.327 157.705 1.00 76.78  ? 699 LYS A O   1 
ATOM 4198 C CB  . LYS A 1 529 ? 187.697 158.772 154.924 1.00 77.51  ? 699 LYS A CB  1 
ATOM 4199 C CG  . LYS A 1 529 ? 186.673 157.850 154.217 1.00 78.76  ? 699 LYS A CG  1 
ATOM 4200 C CD  . LYS A 1 529 ? 186.686 158.011 152.677 1.00 78.74  ? 699 LYS A CD  1 
ATOM 4201 C CE  . LYS A 1 529 ? 185.249 158.012 152.104 1.00 80.30  ? 699 LYS A CE  1 
ATOM 4202 N NZ  . LYS A 1 529 ? 185.140 158.580 150.716 1.00 79.39  ? 699 LYS A NZ  1 
ATOM 4203 N N   . ALA A 1 530 ? 188.415 161.163 156.896 1.00 76.23  ? 700 ALA A N   1 
ATOM 4204 C CA  . ALA A 1 530 ? 189.352 162.139 157.441 1.00 75.55  ? 700 ALA A CA  1 
ATOM 4205 C C   . ALA A 1 530 ? 189.094 162.387 158.937 1.00 75.18  ? 700 ALA A C   1 
ATOM 4206 O O   . ALA A 1 530 ? 187.998 162.094 159.431 1.00 75.29  ? 700 ALA A O   1 
ATOM 4207 C CB  . ALA A 1 530 ? 189.254 163.437 156.654 1.00 75.46  ? 700 ALA A CB  1 
ATOM 4208 N N   . PRO A 1 531 ? 190.106 162.905 159.672 1.00 74.69  ? 701 PRO A N   1 
ATOM 4209 C CA  . PRO A 1 531 ? 189.884 163.294 161.071 1.00 74.33  ? 701 PRO A CA  1 
ATOM 4210 C C   . PRO A 1 531 ? 189.018 164.553 161.177 1.00 73.95  ? 701 PRO A C   1 
ATOM 4211 O O   . PRO A 1 531 ? 189.531 165.678 161.182 1.00 73.95  ? 701 PRO A O   1 
ATOM 4212 C CB  . PRO A 1 531 ? 191.297 163.546 161.600 1.00 74.22  ? 701 PRO A CB  1 
ATOM 4213 C CG  . PRO A 1 531 ? 192.093 163.880 160.409 1.00 74.59  ? 701 PRO A CG  1 
ATOM 4214 C CD  . PRO A 1 531 ? 191.501 163.132 159.254 1.00 74.63  ? 701 PRO A CD  1 
ATOM 4215 N N   . ILE A 1 532 ? 187.706 164.352 161.252 1.00 73.42  ? 702 ILE A N   1 
ATOM 4216 C CA  . ILE A 1 532 ? 186.767 165.455 161.339 1.00 73.09  ? 702 ILE A CA  1 
ATOM 4217 C C   . ILE A 1 532 ? 185.796 165.280 162.495 1.00 72.97  ? 702 ILE A C   1 
ATOM 4218 O O   . ILE A 1 532 ? 185.339 164.168 162.775 1.00 72.85  ? 702 ILE A O   1 
ATOM 4219 C CB  . ILE A 1 532 ? 185.930 165.580 160.021 1.00 73.13  ? 702 ILE A CB  1 
ATOM 4220 C CG1 . ILE A 1 532 ? 186.840 165.856 158.816 1.00 73.35  ? 702 ILE A CG1 1 
ATOM 4221 C CG2 . ILE A 1 532 ? 184.846 166.665 160.134 1.00 72.31  ? 702 ILE A CG2 1 
ATOM 4222 C CD1 . ILE A 1 532 ? 186.183 165.630 157.451 1.00 73.25  ? 702 ILE A CD1 1 
ATOM 4223 N N   . LEU A 1 533 ? 185.481 166.392 163.151 1.00 72.80  ? 703 LEU A N   1 
ATOM 4224 C CA  . LEU A 1 533 ? 184.508 166.412 164.229 1.00 72.90  ? 703 LEU A CA  1 
ATOM 4225 C C   . LEU A 1 533 ? 183.427 167.399 163.800 1.00 73.24  ? 703 LEU A C   1 
ATOM 4226 O O   . LEU A 1 533 ? 183.719 168.494 163.314 1.00 73.36  ? 703 LEU A O   1 
ATOM 4227 C CB  . LEU A 1 533 ? 185.116 166.777 165.581 1.00 72.46  ? 703 LEU A CB  1 
ATOM 4228 C CG  . LEU A 1 533 ? 185.877 165.666 166.327 1.00 72.09  ? 703 LEU A CG  1 
ATOM 4229 C CD1 . LEU A 1 533 ? 186.379 166.181 167.673 1.00 71.28  ? 703 LEU A CD1 1 
ATOM 4230 C CD2 . LEU A 1 533 ? 185.048 164.388 166.520 1.00 70.65  ? 703 LEU A CD2 1 
ATOM 4231 N N   . LEU A 1 534 ? 182.179 166.987 163.944 1.00 73.40  ? 704 LEU A N   1 
ATOM 4232 C CA  . LEU A 1 534 ? 181.058 167.804 163.551 1.00 73.86  ? 704 LEU A CA  1 
ATOM 4233 C C   . LEU A 1 534 ? 180.282 168.180 164.806 1.00 73.61  ? 704 LEU A C   1 
ATOM 4234 O O   . LEU A 1 534 ? 179.856 167.302 165.546 1.00 74.21  ? 704 LEU A O   1 
ATOM 4235 C CB  . LEU A 1 534 ? 180.208 166.976 162.604 1.00 74.06  ? 704 LEU A CB  1 
ATOM 4236 C CG  . LEU A 1 534 ? 179.490 167.686 161.483 1.00 76.06  ? 704 LEU A CG  1 
ATOM 4237 C CD1 . LEU A 1 534 ? 179.332 166.764 160.292 1.00 78.32  ? 704 LEU A CD1 1 
ATOM 4238 C CD2 . LEU A 1 534 ? 178.141 168.093 161.986 1.00 79.35  ? 704 LEU A CD2 1 
ATOM 4239 N N   . ALA A 1 535 ? 180.129 169.474 165.069 1.00 72.99  ? 705 ALA A N   1 
ATOM 4240 C CA  . ALA A 1 535 ? 179.414 169.929 166.266 1.00 72.31  ? 705 ALA A CA  1 
ATOM 4241 C C   . ALA A 1 535 ? 178.005 170.403 165.938 1.00 72.01  ? 705 ALA A C   1 
ATOM 4242 O O   . ALA A 1 535 ? 177.795 171.079 164.933 1.00 72.50  ? 705 ALA A O   1 
ATOM 4243 C CB  . ALA A 1 535 ? 180.189 171.024 166.953 1.00 72.31  ? 705 ALA A CB  1 
ATOM 4244 N N   . LEU A 1 536 ? 177.048 170.077 166.815 1.00 71.19  ? 706 LEU A N   1 
ATOM 4245 C CA  . LEU A 1 536 ? 175.623 170.406 166.531 1.00 70.55  ? 706 LEU A CA  1 
ATOM 4246 C C   . LEU A 1 536 ? 175.141 171.592 167.370 1.00 69.84  ? 706 LEU A C   1 
ATOM 4247 O O   . LEU A 1 536 ? 175.518 171.668 168.555 1.00 69.70  ? 706 LEU A O   1 
ATOM 4248 C CB  . LEU A 1 536 ? 174.771 169.167 166.823 1.00 70.39  ? 706 LEU A CB  1 
ATOM 4249 C CG  . LEU A 1 536 ? 174.572 168.209 165.651 1.00 73.33  ? 706 LEU A CG  1 
ATOM 4250 C CD1 . LEU A 1 536 ? 175.892 167.911 164.956 1.00 75.35  ? 706 LEU A CD1 1 
ATOM 4251 C CD2 . LEU A 1 536 ? 173.908 166.923 166.114 1.00 75.22  ? 706 LEU A CD2 1 
ATOM 4252 N N   . VAL A 1 537 ? 174.326 172.468 166.777 1.00 69.02  ? 707 VAL A N   1 
ATOM 4253 C CA  . VAL A 1 537 ? 173.749 173.604 167.486 1.00 68.28  ? 707 VAL A CA  1 
ATOM 4254 C C   . VAL A 1 537 ? 172.251 173.432 167.347 1.00 68.19  ? 707 VAL A C   1 
ATOM 4255 O O   . VAL A 1 537 ? 171.723 173.489 166.233 1.00 68.75  ? 707 VAL A O   1 
ATOM 4256 C CB  . VAL A 1 537 ? 174.169 174.945 166.917 1.00 67.82  ? 707 VAL A CB  1 
ATOM 4257 C CG1 . VAL A 1 537 ? 173.559 176.044 167.750 1.00 67.08  ? 707 VAL A CG1 1 
ATOM 4258 C CG2 . VAL A 1 537 ? 175.676 175.070 166.905 1.00 67.52  ? 707 VAL A CG2 1 
ATOM 4259 N N   . ALA A 1 538 ? 171.562 173.210 168.461 1.00 67.68  ? 708 ALA A N   1 
ATOM 4260 C CA  . ALA A 1 538 ? 170.125 172.977 168.403 1.00 67.87  ? 708 ALA A CA  1 
ATOM 4261 C C   . ALA A 1 538 ? 169.265 173.888 169.272 1.00 68.11  ? 708 ALA A C   1 
ATOM 4262 O O   . ALA A 1 538 ? 169.783 174.628 170.107 1.00 67.75  ? 708 ALA A O   1 
ATOM 4263 C CB  . ALA A 1 538 ? 169.852 171.527 168.760 1.00 67.56  ? 708 ALA A CB  1 
ATOM 4264 N N   . GLY A 1 539 ? 167.944 173.791 169.078 1.00 68.14  ? 709 GLY A N   1 
ATOM 4265 C CA  . GLY A 1 539 ? 166.958 174.557 169.847 1.00 68.58  ? 709 GLY A CA  1 
ATOM 4266 C C   . GLY A 1 539 ? 167.146 176.049 169.772 1.00 69.17  ? 709 GLY A C   1 
ATOM 4267 O O   . GLY A 1 539 ? 167.513 176.574 168.721 1.00 69.94  ? 709 GLY A O   1 
ATOM 4268 N N   . GLU A 1 540 ? 166.916 176.729 170.890 1.00 69.37  ? 710 GLU A N   1 
ATOM 4269 C CA  . GLU A 1 540 ? 167.045 178.179 170.963 1.00 69.59  ? 710 GLU A CA  1 
ATOM 4270 C C   . GLU A 1 540 ? 168.425 178.678 170.556 1.00 69.35  ? 710 GLU A C   1 
ATOM 4271 O O   . GLU A 1 540 ? 168.573 179.786 170.057 1.00 68.92  ? 710 GLU A O   1 
ATOM 4272 C CB  . GLU A 1 540 ? 166.668 178.699 172.357 1.00 69.80  ? 710 GLU A CB  1 
ATOM 4273 C CG  . GLU A 1 540 ? 165.217 178.404 172.784 1.00 72.12  ? 710 GLU A CG  1 
ATOM 4274 C CD  . GLU A 1 540 ? 164.172 179.214 172.013 1.00 76.56  ? 710 GLU A CD  1 
ATOM 4275 O OE1 . GLU A 1 540 ? 164.482 179.716 170.908 1.00 78.47  ? 710 GLU A OE1 1 
ATOM 4276 O OE2 . GLU A 1 540 ? 163.025 179.343 172.508 1.00 78.27  ? 710 GLU A OE2 1 
ATOM 4277 N N   . ALA A 1 541 ? 169.433 177.842 170.758 1.00 69.77  ? 711 ALA A N   1 
ATOM 4278 C CA  . ALA A 1 541 ? 170.797 178.201 170.405 1.00 69.75  ? 711 ALA A CA  1 
ATOM 4279 C C   . ALA A 1 541 ? 170.982 178.331 168.881 1.00 70.12  ? 711 ALA A C   1 
ATOM 4280 O O   . ALA A 1 541 ? 171.751 179.172 168.421 1.00 70.05  ? 711 ALA A O   1 
ATOM 4281 C CB  . ALA A 1 541 ? 171.755 177.187 170.970 1.00 69.18  ? 711 ALA A CB  1 
ATOM 4282 N N   . ALA A 1 542 ? 170.281 177.512 168.097 1.00 70.49  ? 712 ALA A N   1 
ATOM 4283 C CA  . ALA A 1 542 ? 170.438 177.574 166.640 1.00 71.07  ? 712 ALA A CA  1 
ATOM 4284 C C   . ALA A 1 542 ? 170.305 178.986 166.088 1.00 71.47  ? 712 ALA A C   1 
ATOM 4285 O O   . ALA A 1 542 ? 171.196 179.472 165.392 1.00 71.45  ? 712 ALA A O   1 
ATOM 4286 C CB  . ALA A 1 542 ? 169.485 176.649 165.937 1.00 70.80  ? 712 ALA A CB  1 
ATOM 4287 N N   . GLY A 1 543 ? 169.193 179.627 166.422 1.00 72.05  ? 713 GLY A N   1 
ATOM 4288 C CA  . GLY A 1 543 ? 168.888 180.970 165.956 1.00 72.91  ? 713 GLY A CA  1 
ATOM 4289 C C   . GLY A 1 543 ? 169.841 182.027 166.410 1.00 73.65  ? 713 GLY A C   1 
ATOM 4290 O O   . GLY A 1 543 ? 170.249 182.890 165.621 1.00 74.28  ? 713 GLY A O   1 
ATOM 4291 N N   . ILE A 1 544 ? 170.214 181.952 167.681 1.00 74.06  ? 714 ILE A N   1 
ATOM 4292 C CA  . ILE A 1 544 ? 171.127 182.913 168.259 1.00 74.07  ? 714 ILE A CA  1 
ATOM 4293 C C   . ILE A 1 544 ? 172.541 182.773 167.704 1.00 75.24  ? 714 ILE A C   1 
ATOM 4294 O O   . ILE A 1 544 ? 173.156 183.782 167.361 1.00 75.85  ? 714 ILE A O   1 
ATOM 4295 C CB  . ILE A 1 544 ? 171.129 182.838 169.811 1.00 73.87  ? 714 ILE A CB  1 
ATOM 4296 C CG1 . ILE A 1 544 ? 169.706 183.009 170.350 1.00 71.77  ? 714 ILE A CG1 1 
ATOM 4297 C CG2 . ILE A 1 544 ? 172.088 183.881 170.406 1.00 72.47  ? 714 ILE A CG2 1 
ATOM 4298 C CD1 . ILE A 1 544 ? 169.587 182.871 171.828 1.00 70.02  ? 714 ILE A CD1 1 
ATOM 4299 N N   . MET A 1 545 ? 173.062 181.549 167.617 1.00 76.12  ? 715 MET A N   1 
ATOM 4300 C CA  . MET A 1 545 ? 174.435 181.352 167.120 1.00 77.45  ? 715 MET A CA  1 
ATOM 4301 C C   . MET A 1 545 ? 174.641 181.878 165.711 1.00 77.22  ? 715 MET A C   1 
ATOM 4302 O O   . MET A 1 545 ? 175.772 182.179 165.319 1.00 77.60  ? 715 MET A O   1 
ATOM 4303 C CB  . MET A 1 545 ? 174.881 179.891 167.160 1.00 78.18  ? 715 MET A CB  1 
ATOM 4304 C CG  . MET A 1 545 ? 174.639 179.168 168.459 1.00 81.61  ? 715 MET A CG  1 
ATOM 4305 S SD  . MET A 1 545 ? 175.894 179.403 169.691 1.00 89.82  ? 715 MET A SD  1 
ATOM 4306 C CE  . MET A 1 545 ? 177.274 178.484 168.982 1.00 89.31  ? 715 MET A CE  1 
ATOM 4307 N N   . GLU A 1 546 ? 173.563 181.995 164.947 1.00 76.92  ? 716 GLU A N   1 
ATOM 4308 C CA  . GLU A 1 546 ? 173.703 182.500 163.587 1.00 77.02  ? 716 GLU A CA  1 
ATOM 4309 C C   . GLU A 1 546 ? 174.286 183.916 163.570 1.00 76.83  ? 716 GLU A C   1 
ATOM 4310 O O   . GLU A 1 546 ? 174.978 184.282 162.632 1.00 76.46  ? 716 GLU A O   1 
ATOM 4311 C CB  . GLU A 1 546 ? 172.406 182.361 162.793 1.00 76.85  ? 716 GLU A CB  1 
ATOM 4312 C CG  . GLU A 1 546 ? 172.155 180.910 162.406 1.00 77.53  ? 716 GLU A CG  1 
ATOM 4313 C CD  . GLU A 1 546 ? 171.216 180.731 161.227 1.00 79.22  ? 716 GLU A CD  1 
ATOM 4314 O OE1 . GLU A 1 546 ? 170.924 181.723 160.506 1.00 80.28  ? 716 GLU A OE1 1 
ATOM 4315 O OE2 . GLU A 1 546 ? 170.778 179.578 161.022 1.00 79.08  ? 716 GLU A OE2 1 
ATOM 4316 N N   . ASN A 1 547 ? 174.053 184.664 164.647 1.00 77.01  ? 717 ASN A N   1 
ATOM 4317 C CA  . ASN A 1 547 ? 174.577 186.016 164.798 1.00 77.53  ? 717 ASN A CA  1 
ATOM 4318 C C   . ASN A 1 547 ? 175.975 186.097 165.387 1.00 77.07  ? 717 ASN A C   1 
ATOM 4319 O O   . ASN A 1 547 ? 176.467 187.178 165.664 1.00 77.23  ? 717 ASN A O   1 
ATOM 4320 C CB  . ASN A 1 547 ? 173.631 186.882 165.620 1.00 77.98  ? 717 ASN A CB  1 
ATOM 4321 C CG  . ASN A 1 547 ? 172.809 187.790 164.749 1.00 80.45  ? 717 ASN A CG  1 
ATOM 4322 O OD1 . ASN A 1 547 ? 171.841 187.346 164.096 1.00 81.60  ? 717 ASN A OD1 1 
ATOM 4323 N ND2 . ASN A 1 547 ? 173.204 189.075 164.694 1.00 79.78  ? 717 ASN A ND2 1 
ATOM 4324 N N   . ILE A 1 548 ? 176.607 184.950 165.580 1.00 76.68  ? 718 ILE A N   1 
ATOM 4325 C CA  . ILE A 1 548 ? 177.943 184.902 166.126 1.00 76.22  ? 718 ILE A CA  1 
ATOM 4326 C C   . ILE A 1 548 ? 178.906 184.504 165.020 1.00 75.98  ? 718 ILE A C   1 
ATOM 4327 O O   . ILE A 1 548 ? 178.632 183.591 164.255 1.00 75.93  ? 718 ILE A O   1 
ATOM 4328 C CB  . ILE A 1 548 ? 178.021 183.908 167.311 1.00 76.47  ? 718 ILE A CB  1 
ATOM 4329 C CG1 . ILE A 1 548 ? 177.090 184.354 168.441 1.00 76.73  ? 718 ILE A CG1 1 
ATOM 4330 C CG2 . ILE A 1 548 ? 179.441 183.809 167.843 1.00 75.88  ? 718 ILE A CG2 1 
ATOM 4331 C CD1 . ILE A 1 548 ? 176.824 183.290 169.487 1.00 78.70  ? 718 ILE A CD1 1 
ATOM 4332 N N   . SER A 1 549 ? 180.040 185.195 164.948 1.00 75.98  ? 719 SER A N   1 
ATOM 4333 C CA  . SER A 1 549 ? 181.070 184.927 163.948 1.00 75.90  ? 719 SER A CA  1 
ATOM 4334 C C   . SER A 1 549 ? 181.626 183.512 164.087 1.00 75.91  ? 719 SER A C   1 
ATOM 4335 O O   . SER A 1 549 ? 181.599 182.937 165.179 1.00 75.95  ? 719 SER A O   1 
ATOM 4336 C CB  . SER A 1 549 ? 182.212 185.929 164.109 1.00 75.96  ? 719 SER A CB  1 
ATOM 4337 O OG  . SER A 1 549 ? 182.871 185.732 165.348 1.00 75.79  ? 719 SER A OG  1 
ATOM 4338 N N   . ASP A 1 550 ? 182.147 182.972 162.984 1.00 76.01  ? 720 ASP A N   1 
ATOM 4339 C CA  . ASP A 1 550 ? 182.730 181.627 162.958 1.00 76.24  ? 720 ASP A CA  1 
ATOM 4340 C C   . ASP A 1 550 ? 183.822 181.460 164.022 1.00 76.18  ? 720 ASP A C   1 
ATOM 4341 O O   . ASP A 1 550 ? 183.826 180.472 164.757 1.00 76.36  ? 720 ASP A O   1 
ATOM 4342 C CB  . ASP A 1 550 ? 183.326 181.285 161.581 1.00 76.42  ? 720 ASP A CB  1 
ATOM 4343 C CG  . ASP A 1 550 ? 182.379 181.576 160.427 1.00 77.68  ? 720 ASP A CG  1 
ATOM 4344 O OD1 . ASP A 1 550 ? 181.390 180.835 160.246 1.00 78.13  ? 720 ASP A OD1 1 
ATOM 4345 O OD2 . ASP A 1 550 ? 182.641 182.544 159.675 1.00 79.36  ? 720 ASP A OD2 1 
ATOM 4346 N N   . ASP A 1 551 ? 184.734 182.428 164.102 1.00 75.78  ? 721 ASP A N   1 
ATOM 4347 C CA  . ASP A 1 551 ? 185.837 182.365 165.067 1.00 75.64  ? 721 ASP A CA  1 
ATOM 4348 C C   . ASP A 1 551 ? 185.401 182.189 166.513 1.00 75.29  ? 721 ASP A C   1 
ATOM 4349 O O   . ASP A 1 551 ? 185.986 181.395 167.253 1.00 75.29  ? 721 ASP A O   1 
ATOM 4350 C CB  . ASP A 1 551 ? 186.781 183.562 164.906 1.00 75.66  ? 721 ASP A CB  1 
ATOM 4351 C CG  . ASP A 1 551 ? 187.574 183.499 163.617 1.00 76.29  ? 721 ASP A CG  1 
ATOM 4352 O OD1 . ASP A 1 551 ? 187.198 182.729 162.702 1.00 78.67  ? 721 ASP A OD1 1 
ATOM 4353 O OD2 . ASP A 1 551 ? 188.573 184.224 163.504 1.00 77.16  ? 721 ASP A OD2 1 
ATOM 4354 N N   . VAL A 1 552 ? 184.365 182.911 166.912 1.00 74.84  ? 722 VAL A N   1 
ATOM 4355 C CA  . VAL A 1 552 ? 183.867 182.797 168.267 1.00 74.27  ? 722 VAL A CA  1 
ATOM 4356 C C   . VAL A 1 552 ? 183.192 181.428 168.434 1.00 74.18  ? 722 VAL A C   1 
ATOM 4357 O O   . VAL A 1 552 ? 183.312 180.798 169.480 1.00 73.95  ? 722 VAL A O   1 
ATOM 4358 C CB  . VAL A 1 552 ? 182.936 183.976 168.613 1.00 74.29  ? 722 VAL A CB  1 
ATOM 4359 C CG1 . VAL A 1 552 ? 182.208 183.742 169.928 1.00 73.99  ? 722 VAL A CG1 1 
ATOM 4360 C CG2 . VAL A 1 552 ? 183.731 185.275 168.662 1.00 73.64  ? 722 VAL A CG2 1 
ATOM 4361 N N   . ILE A 1 553 ? 182.521 180.950 167.387 1.00 74.08  ? 723 ILE A N   1 
ATOM 4362 C CA  . ILE A 1 553 ? 181.864 179.641 167.458 1.00 74.16  ? 723 ILE A CA  1 
ATOM 4363 C C   . ILE A 1 553 ? 182.909 178.526 167.583 1.00 74.31  ? 723 ILE A C   1 
ATOM 4364 O O   . ILE A 1 553 ? 182.835 177.676 168.473 1.00 74.39  ? 723 ILE A O   1 
ATOM 4365 C CB  . ILE A 1 553 ? 180.935 179.389 166.263 1.00 73.99  ? 723 ILE A CB  1 
ATOM 4366 C CG1 . ILE A 1 553 ? 179.768 180.383 166.283 1.00 74.07  ? 723 ILE A CG1 1 
ATOM 4367 C CG2 . ILE A 1 553 ? 180.395 177.966 166.310 1.00 74.31  ? 723 ILE A CG2 1 
ATOM 4368 C CD1 . ILE A 1 553 ? 178.949 180.446 164.989 1.00 74.09  ? 723 ILE A CD1 1 
ATOM 4369 N N   . VAL A 1 554 ? 183.891 178.559 166.691 1.00 74.45  ? 724 VAL A N   1 
ATOM 4370 C CA  . VAL A 1 554 ? 184.972 177.585 166.670 1.00 74.35  ? 724 VAL A CA  1 
ATOM 4371 C C   . VAL A 1 554 ? 185.734 177.622 167.999 1.00 74.33  ? 724 VAL A C   1 
ATOM 4372 O O   . VAL A 1 554 ? 186.124 176.580 168.523 1.00 74.57  ? 724 VAL A O   1 
ATOM 4373 C CB  . VAL A 1 554 ? 185.927 177.849 165.465 1.00 74.51  ? 724 VAL A CB  1 
ATOM 4374 C CG1 . VAL A 1 554 ? 187.179 176.972 165.536 1.00 74.47  ? 724 VAL A CG1 1 
ATOM 4375 C CG2 . VAL A 1 554 ? 185.193 177.640 164.142 1.00 73.78  ? 724 VAL A CG2 1 
ATOM 4376 N N   . GLY A 1 555 ? 185.926 178.827 168.542 1.00 74.18  ? 725 GLY A N   1 
ATOM 4377 C CA  . GLY A 1 555 ? 186.627 179.016 169.817 1.00 73.47  ? 725 GLY A CA  1 
ATOM 4378 C C   . GLY A 1 555 ? 185.918 178.257 170.920 1.00 73.22  ? 725 GLY A C   1 
ATOM 4379 O O   . GLY A 1 555 ? 186.544 177.546 171.701 1.00 73.28  ? 725 GLY A O   1 
ATOM 4380 N N   . ARG A 1 556 ? 184.597 178.385 170.959 1.00 72.96  ? 726 ARG A N   1 
ATOM 4381 C CA  . ARG A 1 556 ? 183.799 177.698 171.955 1.00 72.77  ? 726 ARG A CA  1 
ATOM 4382 C C   . ARG A 1 556 ? 183.940 176.183 171.812 1.00 72.87  ? 726 ARG A C   1 
ATOM 4383 O O   . ARG A 1 556 ? 184.115 175.493 172.824 1.00 73.29  ? 726 ARG A O   1 
ATOM 4384 C CB  . ARG A 1 556 ? 182.342 178.152 171.897 1.00 72.68  ? 726 ARG A CB  1 
ATOM 4385 C CG  . ARG A 1 556 ? 182.153 179.576 172.381 1.00 72.37  ? 726 ARG A CG  1 
ATOM 4386 C CD  . ARG A 1 556 ? 180.697 179.934 172.518 1.00 73.34  ? 726 ARG A CD  1 
ATOM 4387 N NE  . ARG A 1 556 ? 180.495 181.376 172.656 1.00 74.60  ? 726 ARG A NE  1 
ATOM 4388 C CZ  . ARG A 1 556 ? 179.308 181.978 172.624 1.00 75.49  ? 726 ARG A CZ  1 
ATOM 4389 N NH1 . ARG A 1 556 ? 178.198 181.264 172.462 1.00 76.66  ? 726 ARG A NH1 1 
ATOM 4390 N NH2 . ARG A 1 556 ? 179.223 183.294 172.758 1.00 75.78  ? 726 ARG A NH2 1 
ATOM 4391 N N   . CYS A 1 557 ? 183.903 175.687 170.567 1.00 72.49  ? 727 CYS A N   1 
ATOM 4392 C CA  . CYS A 1 557 ? 184.058 174.258 170.254 1.00 72.42  ? 727 CYS A CA  1 
ATOM 4393 C C   . CYS A 1 557 ? 185.376 173.726 170.795 1.00 72.31  ? 727 CYS A C   1 
ATOM 4394 O O   . CYS A 1 557 ? 185.425 172.692 171.475 1.00 72.38  ? 727 CYS A O   1 
ATOM 4395 C CB  . CYS A 1 557 ? 184.083 174.042 168.746 1.00 72.42  ? 727 CYS A CB  1 
ATOM 4396 S SG  . CYS A 1 557 ? 182.507 174.154 167.913 1.00 74.65  ? 727 CYS A SG  1 
ATOM 4397 N N   . LEU A 1 558 ? 186.450 174.441 170.472 1.00 71.92  ? 728 LEU A N   1 
ATOM 4398 C CA  . LEU A 1 558 ? 187.787 174.071 170.911 1.00 71.61  ? 728 LEU A CA  1 
ATOM 4399 C C   . LEU A 1 558 ? 187.851 174.082 172.429 1.00 71.27  ? 728 LEU A C   1 
ATOM 4400 O O   . LEU A 1 558 ? 188.424 173.181 173.042 1.00 71.32  ? 728 LEU A O   1 
ATOM 4401 C CB  . LEU A 1 558 ? 188.827 175.033 170.334 1.00 71.74  ? 728 LEU A CB  1 
ATOM 4402 C CG  . LEU A 1 558 ? 188.869 175.152 168.809 1.00 72.37  ? 728 LEU A CG  1 
ATOM 4403 C CD1 . LEU A 1 558 ? 190.084 175.950 168.365 1.00 72.64  ? 728 LEU A CD1 1 
ATOM 4404 C CD2 . LEU A 1 558 ? 188.863 173.774 168.163 1.00 72.46  ? 728 LEU A CD2 1 
ATOM 4405 N N   . ALA A 1 559 ? 187.255 175.103 173.039 1.00 70.78  ? 729 ALA A N   1 
ATOM 4406 C CA  . ALA A 1 559 ? 187.254 175.200 174.495 1.00 70.26  ? 729 ALA A CA  1 
ATOM 4407 C C   . ALA A 1 559 ? 186.611 173.955 175.086 1.00 70.02  ? 729 ALA A C   1 
ATOM 4408 O O   . ALA A 1 559 ? 187.171 173.347 175.992 1.00 69.96  ? 729 ALA A O   1 
ATOM 4409 C CB  . ALA A 1 559 ? 186.546 176.462 174.970 1.00 70.16  ? 729 ALA A CB  1 
ATOM 4410 N N   . ILE A 1 560 ? 185.461 173.553 174.543 1.00 69.84  ? 730 ILE A N   1 
ATOM 4411 C CA  . ILE A 1 560 ? 184.759 172.364 175.030 1.00 69.57  ? 730 ILE A CA  1 
ATOM 4412 C C   . ILE A 1 560 ? 185.646 171.123 174.925 1.00 69.81  ? 730 ILE A C   1 
ATOM 4413 O O   . ILE A 1 560 ? 185.870 170.425 175.929 1.00 70.12  ? 730 ILE A O   1 
ATOM 4414 C CB  . ILE A 1 560 ? 183.415 172.150 174.303 1.00 69.43  ? 730 ILE A CB  1 
ATOM 4415 C CG1 . ILE A 1 560 ? 182.439 173.268 174.681 1.00 69.42  ? 730 ILE A CG1 1 
ATOM 4416 C CG2 . ILE A 1 560 ? 182.811 170.784 174.651 1.00 68.54  ? 730 ILE A CG2 1 
ATOM 4417 C CD1 . ILE A 1 560 ? 181.446 173.610 173.594 1.00 67.56  ? 730 ILE A CD1 1 
ATOM 4418 N N   . LEU A 1 561 ? 186.172 170.881 173.723 1.00 69.66  ? 731 LEU A N   1 
ATOM 4419 C CA  . LEU A 1 561 ? 187.039 169.734 173.463 1.00 69.51  ? 731 LEU A CA  1 
ATOM 4420 C C   . LEU A 1 561 ? 188.291 169.708 174.346 1.00 69.88  ? 731 LEU A C   1 
ATOM 4421 O O   . LEU A 1 561 ? 188.656 168.648 174.864 1.00 69.91  ? 731 LEU A O   1 
ATOM 4422 C CB  . LEU A 1 561 ? 187.391 169.650 171.978 1.00 69.19  ? 731 LEU A CB  1 
ATOM 4423 C CG  . LEU A 1 561 ? 186.187 169.428 171.049 1.00 69.02  ? 731 LEU A CG  1 
ATOM 4424 C CD1 . LEU A 1 561 ? 186.516 169.738 169.583 1.00 67.54  ? 731 LEU A CD1 1 
ATOM 4425 C CD2 . LEU A 1 561 ? 185.625 168.015 171.203 1.00 68.57  ? 731 LEU A CD2 1 
ATOM 4426 N N   . LYS A 1 562 ? 188.931 170.864 174.530 1.00 70.09  ? 732 LYS A N   1 
ATOM 4427 C CA  . LYS A 1 562 ? 190.123 170.950 175.377 1.00 70.49  ? 732 LYS A CA  1 
ATOM 4428 C C   . LYS A 1 562 ? 189.753 170.489 176.787 1.00 70.40  ? 732 LYS A C   1 
ATOM 4429 O O   . LYS A 1 562 ? 190.499 169.749 177.433 1.00 70.21  ? 732 LYS A O   1 
ATOM 4430 C CB  . LYS A 1 562 ? 190.662 172.379 175.435 1.00 70.58  ? 732 LYS A CB  1 
ATOM 4431 C CG  . LYS A 1 562 ? 191.327 172.893 174.119 1.00 70.66  ? 732 LYS A CG  1 
ATOM 4432 C CD  . LYS A 1 562 ? 191.840 174.317 174.394 1.00 71.28  ? 732 LYS A CD  1 
ATOM 4433 C CE  . LYS A 1 562 ? 191.945 175.111 173.072 1.00 71.41  ? 732 LYS A CE  1 
ATOM 4434 N NZ  . LYS A 1 562 ? 193.177 174.678 172.298 1.00 73.22  ? 732 LYS A NZ  1 
ATOM 4435 N N   . GLY A 1 563 ? 188.578 170.920 177.239 1.00 70.33  ? 733 GLY A N   1 
ATOM 4436 C CA  . GLY A 1 563 ? 188.067 170.557 178.550 1.00 70.35  ? 733 GLY A CA  1 
ATOM 4437 C C   . GLY A 1 563 ? 187.875 169.059 178.692 1.00 70.41  ? 733 GLY A C   1 
ATOM 4438 O O   . GLY A 1 563 ? 188.023 168.520 179.783 1.00 70.57  ? 733 GLY A O   1 
ATOM 4439 N N   . ILE A 1 564 ? 187.550 168.382 177.595 1.00 70.52  ? 734 ILE A N   1 
ATOM 4440 C CA  . ILE A 1 564 ? 187.350 166.936 177.640 1.00 70.56  ? 734 ILE A CA  1 
ATOM 4441 C C   . ILE A 1 564 ? 188.639 166.115 177.473 1.00 70.81  ? 734 ILE A C   1 
ATOM 4442 O O   . ILE A 1 564 ? 188.969 165.289 178.322 1.00 70.43  ? 734 ILE A O   1 
ATOM 4443 C CB  . ILE A 1 564 ? 186.321 166.467 176.586 1.00 70.48  ? 734 ILE A CB  1 
ATOM 4444 C CG1 . ILE A 1 564 ? 184.940 167.056 176.881 1.00 70.90  ? 734 ILE A CG1 1 
ATOM 4445 C CG2 . ILE A 1 564 ? 186.238 164.938 176.546 1.00 70.25  ? 734 ILE A CG2 1 
ATOM 4446 C CD1 . ILE A 1 564 ? 183.987 167.028 175.684 1.00 69.64  ? 734 ILE A CD1 1 
ATOM 4447 N N   . PHE A 1 565 ? 189.339 166.333 176.362 1.00 71.16  ? 735 PHE A N   1 
ATOM 4448 C CA  . PHE A 1 565 ? 190.542 165.572 176.028 1.00 71.40  ? 735 PHE A CA  1 
ATOM 4449 C C   . PHE A 1 565 ? 191.882 166.108 176.534 1.00 71.92  ? 735 PHE A C   1 
ATOM 4450 O O   . PHE A 1 565 ? 192.912 165.431 176.399 1.00 71.61  ? 735 PHE A O   1 
ATOM 4451 C CB  . PHE A 1 565 ? 190.596 165.354 174.506 1.00 71.03  ? 735 PHE A CB  1 
ATOM 4452 C CG  . PHE A 1 565 ? 189.369 164.687 173.942 1.00 70.85  ? 735 PHE A CG  1 
ATOM 4453 C CD1 . PHE A 1 565 ? 189.165 163.317 174.107 1.00 70.35  ? 735 PHE A CD1 1 
ATOM 4454 C CD2 . PHE A 1 565 ? 188.415 165.432 173.244 1.00 70.13  ? 735 PHE A CD2 1 
ATOM 4455 C CE1 . PHE A 1 565 ? 188.023 162.700 173.588 1.00 70.44  ? 735 PHE A CE1 1 
ATOM 4456 C CE2 . PHE A 1 565 ? 187.281 164.825 172.721 1.00 69.11  ? 735 PHE A CE2 1 
ATOM 4457 C CZ  . PHE A 1 565 ? 187.084 163.457 172.887 1.00 69.91  ? 735 PHE A CZ  1 
ATOM 4458 N N   . GLY A 1 566 ? 191.869 167.305 177.114 1.00 72.61  ? 736 GLY A N   1 
ATOM 4459 C CA  . GLY A 1 566 ? 193.091 167.918 177.624 1.00 73.47  ? 736 GLY A CA  1 
ATOM 4460 C C   . GLY A 1 566 ? 193.514 169.060 176.721 1.00 74.27  ? 736 GLY A C   1 
ATOM 4461 O O   . GLY A 1 566 ? 193.396 168.969 175.497 1.00 74.26  ? 736 GLY A O   1 
ATOM 4462 N N   . SER A 1 567 ? 194.023 170.140 177.317 1.00 75.17  ? 737 SER A N   1 
ATOM 4463 C CA  . SER A 1 567 ? 194.395 171.338 176.517 1.00 75.99  ? 737 SER A CA  1 
ATOM 4464 C C   . SER A 1 567 ? 195.426 170.982 175.440 1.00 76.08  ? 737 SER A C   1 
ATOM 4465 O O   . SER A 1 567 ? 195.157 171.274 174.258 1.00 75.92  ? 737 SER A O   1 
ATOM 4466 C CB  . SER A 1 567 ? 194.900 172.443 177.408 1.00 76.11  ? 737 SER A CB  1 
ATOM 4467 O OG  . SER A 1 567 ? 195.248 173.587 176.643 1.00 77.86  ? 737 SER A OG  1 
ATOM 4468 N N   . SER A 1 568 ? 196.554 170.374 175.823 1.00 76.34  ? 738 SER A N   1 
ATOM 4469 C CA  . SER A 1 568 ? 197.621 170.105 174.856 1.00 76.73  ? 738 SER A CA  1 
ATOM 4470 C C   . SER A 1 568 ? 197.227 169.158 173.716 1.00 76.83  ? 738 SER A C   1 
ATOM 4471 O O   . SER A 1 568 ? 197.819 169.209 172.638 1.00 77.32  ? 738 SER A O   1 
ATOM 4472 C CB  . SER A 1 568 ? 198.858 169.563 175.567 1.00 76.88  ? 738 SER A CB  1 
ATOM 4473 O OG  . SER A 1 568 ? 198.606 168.271 176.083 1.00 77.75  ? 738 SER A OG  1 
ATOM 4474 N N   . ALA A 1 569 ? 196.232 168.305 173.949 1.00 76.64  ? 739 ALA A N   1 
ATOM 4475 C CA  . ALA A 1 569 ? 195.785 167.337 172.941 1.00 76.16  ? 739 ALA A CA  1 
ATOM 4476 C C   . ALA A 1 569 ? 195.052 167.908 171.722 1.00 75.97  ? 739 ALA A C   1 
ATOM 4477 O O   . ALA A 1 569 ? 195.148 167.337 170.637 1.00 76.27  ? 739 ALA A O   1 
ATOM 4478 C CB  . ALA A 1 569 ? 194.943 166.238 173.595 1.00 75.97  ? 739 ALA A CB  1 
ATOM 4479 N N   . VAL A 1 570 ? 194.321 169.008 171.905 1.00 75.58  ? 740 VAL A N   1 
ATOM 4480 C CA  . VAL A 1 570 ? 193.512 169.630 170.832 1.00 74.88  ? 740 VAL A CA  1 
ATOM 4481 C C   . VAL A 1 570 ? 194.151 170.758 170.007 1.00 74.62  ? 740 VAL A C   1 
ATOM 4482 O O   . VAL A 1 570 ? 194.218 171.916 170.458 1.00 74.43  ? 740 VAL A O   1 
ATOM 4483 C CB  . VAL A 1 570 ? 192.168 170.145 171.395 1.00 74.96  ? 740 VAL A CB  1 
ATOM 4484 C CG1 . VAL A 1 570 ? 191.200 170.503 170.254 1.00 74.53  ? 740 VAL A CG1 1 
ATOM 4485 C CG2 . VAL A 1 570 ? 191.547 169.108 172.338 1.00 74.90  ? 740 VAL A CG2 1 
ATOM 4486 N N   . PRO A 1 571 ? 194.538 170.447 168.756 1.00 74.50  ? 741 PRO A N   1 
ATOM 4487 C CA  . PRO A 1 571 ? 195.228 171.420 167.924 1.00 74.61  ? 741 PRO A CA  1 
ATOM 4488 C C   . PRO A 1 571 ? 194.250 172.354 167.250 1.00 74.86  ? 741 PRO A C   1 
ATOM 4489 O O   . PRO A 1 571 ? 193.042 172.132 167.320 1.00 75.04  ? 741 PRO A O   1 
ATOM 4490 C CB  . PRO A 1 571 ? 195.884 170.547 166.856 1.00 74.54  ? 741 PRO A CB  1 
ATOM 4491 C CG  . PRO A 1 571 ? 194.956 169.403 166.698 1.00 74.19  ? 741 PRO A CG  1 
ATOM 4492 C CD  . PRO A 1 571 ? 194.321 169.173 168.044 1.00 74.48  ? 741 PRO A CD  1 
ATOM 4493 N N   . GLN A 1 572 ? 194.768 173.378 166.581 1.00 75.12  ? 742 GLN A N   1 
ATOM 4494 C CA  . GLN A 1 572 ? 193.908 174.306 165.864 1.00 75.32  ? 742 GLN A CA  1 
ATOM 4495 C C   . GLN A 1 572 ? 193.392 173.560 164.647 1.00 75.04  ? 742 GLN A C   1 
ATOM 4496 O O   . GLN A 1 572 ? 194.130 172.767 164.050 1.00 75.06  ? 742 GLN A O   1 
ATOM 4497 C CB  . GLN A 1 572 ? 194.666 175.566 165.442 1.00 75.60  ? 742 GLN A CB  1 
ATOM 4498 C CG  . GLN A 1 572 ? 194.912 176.559 166.586 1.00 77.17  ? 742 GLN A CG  1 
ATOM 4499 C CD  . GLN A 1 572 ? 193.619 177.106 167.192 1.00 78.90  ? 742 GLN A CD  1 
ATOM 4500 O OE1 . GLN A 1 572 ? 193.439 177.087 168.414 1.00 80.21  ? 742 GLN A OE1 1 
ATOM 4501 N NE2 . GLN A 1 572 ? 192.715 177.593 166.340 1.00 78.64  ? 742 GLN A NE2 1 
ATOM 4502 N N   . PRO A 1 573 ? 192.116 173.772 164.296 1.00 74.87  ? 743 PRO A N   1 
ATOM 4503 C CA  . PRO A 1 573 ? 191.578 173.102 163.114 1.00 74.70  ? 743 PRO A CA  1 
ATOM 4504 C C   . PRO A 1 573 ? 192.211 173.643 161.833 1.00 74.51  ? 743 PRO A C   1 
ATOM 4505 O O   . PRO A 1 573 ? 192.544 174.827 161.757 1.00 74.55  ? 743 PRO A O   1 
ATOM 4506 C CB  . PRO A 1 573 ? 190.088 173.446 163.165 1.00 74.61  ? 743 PRO A CB  1 
ATOM 4507 C CG  . PRO A 1 573 ? 190.019 174.706 163.950 1.00 74.72  ? 743 PRO A CG  1 
ATOM 4508 C CD  . PRO A 1 573 ? 191.111 174.619 164.961 1.00 74.80  ? 743 PRO A CD  1 
ATOM 4509 N N   . LYS A 1 574 ? 192.390 172.769 160.846 1.00 74.26  ? 744 LYS A N   1 
ATOM 4510 C CA  . LYS A 1 574 ? 192.974 173.159 159.569 1.00 73.99  ? 744 LYS A CA  1 
ATOM 4511 C C   . LYS A 1 574 ? 191.924 173.836 158.689 1.00 73.74  ? 744 LYS A C   1 
ATOM 4512 O O   . LYS A 1 574 ? 192.245 174.731 157.916 1.00 73.83  ? 744 LYS A O   1 
ATOM 4513 C CB  . LYS A 1 574 ? 193.626 171.953 158.885 1.00 73.88  ? 744 LYS A CB  1 
ATOM 4514 C CG  . LYS A 1 574 ? 194.915 171.489 159.580 1.00 74.74  ? 744 LYS A CG  1 
ATOM 4515 C CD  . LYS A 1 574 ? 196.152 172.240 159.050 1.00 75.76  ? 744 LYS A CD  1 
ATOM 4516 C CE  . LYS A 1 574 ? 197.076 172.719 160.163 1.00 75.78  ? 744 LYS A CE  1 
ATOM 4517 N NZ  . LYS A 1 574 ? 197.745 171.606 160.889 1.00 76.39  ? 744 LYS A NZ  1 
ATOM 4518 N N   . GLU A 1 575 ? 190.667 173.416 158.833 1.00 73.63  ? 745 GLU A N   1 
ATOM 4519 C CA  . GLU A 1 575 ? 189.536 173.976 158.081 1.00 73.45  ? 745 GLU A CA  1 
ATOM 4520 C C   . GLU A 1 575 ? 188.273 173.928 158.927 1.00 72.89  ? 745 GLU A C   1 
ATOM 4521 O O   . GLU A 1 575 ? 188.018 172.927 159.597 1.00 72.93  ? 745 GLU A O   1 
ATOM 4522 C CB  . GLU A 1 575 ? 189.277 173.182 156.792 1.00 73.59  ? 745 GLU A CB  1 
ATOM 4523 C CG  . GLU A 1 575 ? 190.367 173.266 155.728 1.00 75.14  ? 745 GLU A CG  1 
ATOM 4524 C CD  . GLU A 1 575 ? 190.444 174.629 155.068 1.00 76.70  ? 745 GLU A CD  1 
ATOM 4525 O OE1 . GLU A 1 575 ? 189.386 175.292 154.957 1.00 77.61  ? 745 GLU A OE1 1 
ATOM 4526 O OE2 . GLU A 1 575 ? 191.561 175.026 154.659 1.00 76.95  ? 745 GLU A OE2 1 
ATOM 4527 N N   . THR A 1 576 ? 187.483 175.000 158.891 1.00 72.41  ? 746 THR A N   1 
ATOM 4528 C CA  . THR A 1 576 ? 186.215 175.053 159.633 1.00 72.05  ? 746 THR A CA  1 
ATOM 4529 C C   . THR A 1 576 ? 185.095 175.657 158.796 1.00 71.76  ? 746 THR A C   1 
ATOM 4530 O O   . THR A 1 576 ? 185.290 176.670 158.124 1.00 72.12  ? 746 THR A O   1 
ATOM 4531 C CB  . THR A 1 576 ? 186.280 175.904 160.898 1.00 71.77  ? 746 THR A CB  1 
ATOM 4532 O OG1 . THR A 1 576 ? 186.709 177.220 160.557 1.00 72.38  ? 746 THR A OG1 1 
ATOM 4533 C CG2 . THR A 1 576 ? 187.212 175.310 161.907 1.00 72.21  ? 746 THR A CG2 1 
ATOM 4534 N N   . VAL A 1 577 ? 183.919 175.040 158.872 1.00 71.08  ? 747 VAL A N   1 
ATOM 4535 C CA  . VAL A 1 577 ? 182.739 175.504 158.166 1.00 70.47  ? 747 VAL A CA  1 
ATOM 4536 C C   . VAL A 1 577 ? 181.615 175.562 159.177 1.00 70.16  ? 747 VAL A C   1 
ATOM 4537 O O   . VAL A 1 577 ? 181.456 174.646 159.985 1.00 69.72  ? 747 VAL A O   1 
ATOM 4538 C CB  . VAL A 1 577 ? 182.288 174.530 157.060 1.00 70.59  ? 747 VAL A CB  1 
ATOM 4539 C CG1 . VAL A 1 577 ? 181.436 175.264 156.042 1.00 69.72  ? 747 VAL A CG1 1 
ATOM 4540 C CG2 . VAL A 1 577 ? 183.484 173.875 156.380 1.00 70.92  ? 747 VAL A CG2 1 
ATOM 4541 N N   . VAL A 1 578 ? 180.829 176.633 159.118 1.00 69.97  ? 748 VAL A N   1 
ATOM 4542 C CA  . VAL A 1 578 ? 179.692 176.809 160.023 1.00 69.78  ? 748 VAL A CA  1 
ATOM 4543 C C   . VAL A 1 578 ? 178.457 177.055 159.184 1.00 69.67  ? 748 VAL A C   1 
ATOM 4544 O O   . VAL A 1 578 ? 178.438 177.978 158.380 1.00 70.19  ? 748 VAL A O   1 
ATOM 4545 C CB  . VAL A 1 578 ? 179.887 178.015 160.968 1.00 69.68  ? 748 VAL A CB  1 
ATOM 4546 C CG1 . VAL A 1 578 ? 178.691 178.184 161.869 1.00 69.62  ? 748 VAL A CG1 1 
ATOM 4547 C CG2 . VAL A 1 578 ? 181.152 177.856 161.799 1.00 69.57  ? 748 VAL A CG2 1 
ATOM 4548 N N   . SER A 1 579 ? 177.419 176.245 159.357 1.00 69.41  ? 749 SER A N   1 
ATOM 4549 C CA  . SER A 1 579 ? 176.197 176.452 158.577 1.00 69.00  ? 749 SER A CA  1 
ATOM 4550 C C   . SER A 1 579 ? 175.314 177.483 159.261 1.00 69.20  ? 749 SER A C   1 
ATOM 4551 O O   . SER A 1 579 ? 175.401 177.677 160.490 1.00 69.29  ? 749 SER A O   1 
ATOM 4552 C CB  . SER A 1 579 ? 175.419 175.143 158.416 1.00 68.67  ? 749 SER A CB  1 
ATOM 4553 O OG  . SER A 1 579 ? 174.716 174.806 159.609 1.00 68.70  ? 749 SER A OG  1 
ATOM 4554 N N   . ARG A 1 580 ? 174.475 178.138 158.461 1.00 69.22  ? 750 ARG A N   1 
ATOM 4555 C CA  . ARG A 1 580 ? 173.510 179.134 158.941 1.00 69.55  ? 750 ARG A CA  1 
ATOM 4556 C C   . ARG A 1 580 ? 172.230 178.959 158.103 1.00 69.71  ? 750 ARG A C   1 
ATOM 4557 O O   . ARG A 1 580 ? 171.924 179.778 157.230 1.00 70.31  ? 750 ARG A O   1 
ATOM 4558 C CB  . ARG A 1 580 ? 174.066 180.557 158.834 1.00 69.24  ? 750 ARG A CB  1 
ATOM 4559 C CG  . ARG A 1 580 ? 175.365 180.771 159.572 1.00 70.76  ? 750 ARG A CG  1 
ATOM 4560 C CD  . ARG A 1 580 ? 175.792 182.223 159.592 1.00 72.97  ? 750 ARG A CD  1 
ATOM 4561 N NE  . ARG A 1 580 ? 176.751 182.493 160.665 1.00 75.84  ? 750 ARG A NE  1 
ATOM 4562 C CZ  . ARG A 1 580 ? 178.052 182.192 160.619 1.00 78.77  ? 750 ARG A CZ  1 
ATOM 4563 N NH1 . ARG A 1 580 ? 178.552 181.581 159.550 1.00 80.57  ? 750 ARG A NH1 1 
ATOM 4564 N NH2 . ARG A 1 580 ? 178.862 182.488 161.642 1.00 77.78  ? 750 ARG A NH2 1 
ATOM 4565 N N   . TRP A 1 581 ? 171.498 177.874 158.351 1.00 69.46  ? 751 TRP A N   1 
ATOM 4566 C CA  . TRP A 1 581 ? 170.297 177.594 157.574 1.00 69.14  ? 751 TRP A CA  1 
ATOM 4567 C C   . TRP A 1 581 ? 169.206 178.657 157.621 1.00 69.30  ? 751 TRP A C   1 
ATOM 4568 O O   . TRP A 1 581 ? 168.540 178.889 156.600 1.00 69.84  ? 751 TRP A O   1 
ATOM 4569 C CB  . TRP A 1 581 ? 169.749 176.181 157.826 1.00 68.76  ? 751 TRP A CB  1 
ATOM 4570 C CG  . TRP A 1 581 ? 170.696 175.121 157.329 1.00 68.66  ? 751 TRP A CG  1 
ATOM 4571 C CD1 . TRP A 1 581 ? 171.598 174.403 158.077 1.00 68.19  ? 751 TRP A CD1 1 
ATOM 4572 C CD2 . TRP A 1 581 ? 170.867 174.686 155.972 1.00 67.62  ? 751 TRP A CD2 1 
ATOM 4573 N NE1 . TRP A 1 581 ? 172.306 173.538 157.265 1.00 68.02  ? 751 TRP A NE1 1 
ATOM 4574 C CE2 . TRP A 1 581 ? 171.881 173.695 155.974 1.00 67.73  ? 751 TRP A CE2 1 
ATOM 4575 C CE3 . TRP A 1 581 ? 170.267 175.038 154.757 1.00 66.94  ? 751 TRP A CE3 1 
ATOM 4576 C CZ2 . TRP A 1 581 ? 172.300 173.052 154.810 1.00 67.81  ? 751 TRP A CZ2 1 
ATOM 4577 C CZ3 . TRP A 1 581 ? 170.681 174.392 153.596 1.00 67.64  ? 751 TRP A CZ3 1 
ATOM 4578 C CH2 . TRP A 1 581 ? 171.694 173.411 153.633 1.00 67.78  ? 751 TRP A CH2 1 
ATOM 4579 N N   . ARG A 1 582 ? 169.006 179.296 158.771 1.00 68.79  ? 752 ARG A N   1 
ATOM 4580 C CA  . ARG A 1 582 ? 167.963 180.330 158.849 1.00 68.62  ? 752 ARG A CA  1 
ATOM 4581 C C   . ARG A 1 582 ? 168.264 181.528 157.936 1.00 68.92  ? 752 ARG A C   1 
ATOM 4582 O O   . ARG A 1 582 ? 167.372 182.044 157.273 1.00 69.55  ? 752 ARG A O   1 
ATOM 4583 C CB  . ARG A 1 582 ? 167.717 180.797 160.290 1.00 67.96  ? 752 ARG A CB  1 
ATOM 4584 C CG  . ARG A 1 582 ? 166.443 181.615 160.474 1.00 66.13  ? 752 ARG A CG  1 
ATOM 4585 C CD  . ARG A 1 582 ? 165.182 180.769 160.199 1.00 65.84  ? 752 ARG A CD  1 
ATOM 4586 N NE  . ARG A 1 582 ? 164.738 179.995 161.362 1.00 65.66  ? 752 ARG A NE  1 
ATOM 4587 C CZ  . ARG A 1 582 ? 163.741 179.113 161.348 1.00 64.55  ? 752 ARG A CZ  1 
ATOM 4588 N NH1 . ARG A 1 582 ? 163.083 178.862 160.225 1.00 66.13  ? 752 ARG A NH1 1 
ATOM 4589 N NH2 . ARG A 1 582 ? 163.401 178.471 162.450 1.00 62.80  ? 752 ARG A NH2 1 
ATOM 4590 N N   . ALA A 1 583 ? 169.522 181.952 157.893 1.00 68.87  ? 753 ALA A N   1 
ATOM 4591 C CA  . ALA A 1 583 ? 169.927 183.088 157.071 1.00 69.18  ? 753 ALA A CA  1 
ATOM 4592 C C   . ALA A 1 583 ? 170.005 182.771 155.582 1.00 69.66  ? 753 ALA A C   1 
ATOM 4593 O O   . ALA A 1 583 ? 170.072 183.689 154.747 1.00 69.71  ? 753 ALA A O   1 
ATOM 4594 C CB  . ALA A 1 583 ? 171.275 183.650 157.559 1.00 68.47  ? 753 ALA A CB  1 
ATOM 4595 N N   . ASP A 1 584 ? 170.036 181.480 155.249 1.00 69.73  ? 754 ASP A N   1 
ATOM 4596 C CA  . ASP A 1 584 ? 170.134 181.075 153.867 1.00 70.12  ? 754 ASP A CA  1 
ATOM 4597 C C   . ASP A 1 584 ? 168.841 181.475 153.145 1.00 70.37  ? 754 ASP A C   1 
ATOM 4598 O O   . ASP A 1 584 ? 167.754 180.963 153.467 1.00 71.26  ? 754 ASP A O   1 
ATOM 4599 C CB  . ASP A 1 584 ? 170.402 179.575 153.806 1.00 70.43  ? 754 ASP A CB  1 
ATOM 4600 C CG  . ASP A 1 584 ? 170.637 179.061 152.384 1.00 72.14  ? 754 ASP A CG  1 
ATOM 4601 O OD1 . ASP A 1 584 ? 170.136 179.679 151.413 1.00 73.70  ? 754 ASP A OD1 1 
ATOM 4602 O OD2 . ASP A 1 584 ? 171.317 178.017 152.243 1.00 72.70  ? 754 ASP A OD2 1 
ATOM 4603 N N   . PRO A 1 585 ? 168.936 182.408 152.178 1.00 69.90  ? 755 PRO A N   1 
ATOM 4604 C CA  . PRO A 1 585 ? 167.723 182.899 151.514 1.00 69.46  ? 755 PRO A CA  1 
ATOM 4605 C C   . PRO A 1 585 ? 166.993 181.838 150.705 1.00 69.45  ? 755 PRO A C   1 
ATOM 4606 O O   . PRO A 1 585 ? 165.816 182.030 150.359 1.00 69.84  ? 755 PRO A O   1 
ATOM 4607 C CB  . PRO A 1 585 ? 168.247 183.994 150.573 1.00 69.55  ? 755 PRO A CB  1 
ATOM 4608 C CG  . PRO A 1 585 ? 169.695 183.653 150.355 1.00 69.43  ? 755 PRO A CG  1 
ATOM 4609 C CD  . PRO A 1 585 ? 170.152 183.061 151.662 1.00 69.70  ? 755 PRO A CD  1 
ATOM 4610 N N   . TRP A 1 586 ? 167.672 180.740 150.391 1.00 69.13  ? 756 TRP A N   1 
ATOM 4611 C CA  . TRP A 1 586 ? 167.056 179.672 149.608 1.00 68.86  ? 756 TRP A CA  1 
ATOM 4612 C C   . TRP A 1 586 ? 166.483 178.566 150.483 1.00 69.09  ? 756 TRP A C   1 
ATOM 4613 O O   . TRP A 1 586 ? 165.909 177.602 149.978 1.00 69.30  ? 756 TRP A O   1 
ATOM 4614 C CB  . TRP A 1 586 ? 168.036 179.122 148.565 1.00 68.44  ? 756 TRP A CB  1 
ATOM 4615 C CG  . TRP A 1 586 ? 168.806 180.218 147.857 1.00 68.20  ? 756 TRP A CG  1 
ATOM 4616 C CD1 . TRP A 1 586 ? 170.169 180.379 147.830 1.00 67.65  ? 756 TRP A CD1 1 
ATOM 4617 C CD2 . TRP A 1 586 ? 168.261 181.314 147.105 1.00 66.83  ? 756 TRP A CD2 1 
ATOM 4618 N NE1 . TRP A 1 586 ? 170.502 181.500 147.107 1.00 67.45  ? 756 TRP A NE1 1 
ATOM 4619 C CE2 . TRP A 1 586 ? 169.355 182.089 146.642 1.00 67.41  ? 756 TRP A CE2 1 
ATOM 4620 C CE3 . TRP A 1 586 ? 166.963 181.716 146.775 1.00 67.52  ? 756 TRP A CE3 1 
ATOM 4621 C CZ2 . TRP A 1 586 ? 169.186 183.249 145.860 1.00 67.03  ? 756 TRP A CZ2 1 
ATOM 4622 C CZ3 . TRP A 1 586 ? 166.791 182.883 145.991 1.00 67.92  ? 756 TRP A CZ3 1 
ATOM 4623 C CH2 . TRP A 1 586 ? 167.902 183.632 145.553 1.00 67.47  ? 756 TRP A CH2 1 
ATOM 4624 N N   . ALA A 1 587 ? 166.635 178.692 151.800 1.00 69.35  ? 757 ALA A N   1 
ATOM 4625 C CA  . ALA A 1 587 ? 166.087 177.676 152.705 1.00 69.20  ? 757 ALA A CA  1 
ATOM 4626 C C   . ALA A 1 587 ? 165.265 178.342 153.800 1.00 69.54  ? 757 ALA A C   1 
ATOM 4627 O O   . ALA A 1 587 ? 164.098 177.995 153.995 1.00 69.20  ? 757 ALA A O   1 
ATOM 4628 C CB  . ALA A 1 587 ? 167.187 176.811 153.298 1.00 68.90  ? 757 ALA A CB  1 
ATOM 4629 N N   . ARG A 1 588 ? 165.877 179.307 154.494 1.00 69.72  ? 758 ARG A N   1 
ATOM 4630 C CA  . ARG A 1 588 ? 165.224 180.042 155.585 1.00 70.44  ? 758 ARG A CA  1 
ATOM 4631 C C   . ARG A 1 588 ? 164.879 179.133 156.760 1.00 70.41  ? 758 ARG A C   1 
ATOM 4632 O O   . ARG A 1 588 ? 163.875 179.349 157.454 1.00 70.76  ? 758 ARG A O   1 
ATOM 4633 C CB  . ARG A 1 588 ? 163.958 180.757 155.098 1.00 70.85  ? 758 ARG A CB  1 
ATOM 4634 C CG  . ARG A 1 588 ? 164.207 181.829 154.034 1.00 72.48  ? 758 ARG A CG  1 
ATOM 4635 C CD  . ARG A 1 588 ? 164.784 183.056 154.641 1.00 75.81  ? 758 ARG A CD  1 
ATOM 4636 N NE  . ARG A 1 588 ? 164.758 184.152 153.684 1.00 81.26  ? 758 ARG A NE  1 
ATOM 4637 C CZ  . ARG A 1 588 ? 165.604 185.190 153.692 1.00 83.38  ? 758 ARG A CZ  1 
ATOM 4638 N NH1 . ARG A 1 588 ? 166.567 185.279 154.611 1.00 82.59  ? 758 ARG A NH1 1 
ATOM 4639 N NH2 . ARG A 1 588 ? 165.499 186.131 152.761 1.00 83.25  ? 758 ARG A NH2 1 
ATOM 4640 N N   . GLY A 1 589 ? 165.709 178.120 156.976 1.00 69.68  ? 759 GLY A N   1 
ATOM 4641 C CA  . GLY A 1 589 ? 165.495 177.183 158.059 1.00 69.57  ? 759 GLY A CA  1 
ATOM 4642 C C   . GLY A 1 589 ? 165.992 175.825 157.626 1.00 69.53  ? 759 GLY A C   1 
ATOM 4643 O O   . GLY A 1 589 ? 166.519 175.684 156.531 1.00 69.92  ? 759 GLY A O   1 
ATOM 4644 N N   . SER A 1 590 ? 165.812 174.814 158.459 1.00 68.88  ? 760 SER A N   1 
ATOM 4645 C CA  . SER A 1 590 ? 166.308 173.500 158.104 1.00 69.12  ? 760 SER A CA  1 
ATOM 4646 C C   . SER A 1 590 ? 165.223 172.556 157.619 1.00 69.31  ? 760 SER A C   1 
ATOM 4647 O O   . SER A 1 590 ? 165.345 171.996 156.525 1.00 70.04  ? 760 SER A O   1 
ATOM 4648 C CB  . SER A 1 590 ? 167.077 172.908 159.276 1.00 69.08  ? 760 SER A CB  1 
ATOM 4649 O OG  . SER A 1 590 ? 166.211 172.723 160.382 1.00 71.16  ? 760 SER A OG  1 
ATOM 4650 N N   . TYR A 1 591 ? 164.169 172.382 158.420 1.00 68.71  ? 761 TYR A N   1 
ATOM 4651 C CA  . TYR A 1 591 ? 163.047 171.529 158.059 1.00 68.99  ? 761 TYR A CA  1 
ATOM 4652 C C   . TYR A 1 591 ? 161.782 171.792 158.882 1.00 70.02  ? 761 TYR A C   1 
ATOM 4653 O O   . TYR A 1 591 ? 161.836 172.405 159.961 1.00 70.57  ? 761 TYR A O   1 
ATOM 4654 C CB  . TYR A 1 591 ? 163.408 170.054 158.019 1.00 68.51  ? 761 TYR A CB  1 
ATOM 4655 C CG  . TYR A 1 591 ? 164.138 169.478 159.217 1.00 68.18  ? 761 TYR A CG  1 
ATOM 4656 C CD1 . TYR A 1 591 ? 163.445 169.004 160.315 1.00 65.44  ? 761 TYR A CD1 1 
ATOM 4657 C CD2 . TYR A 1 591 ? 165.529 169.343 159.207 1.00 67.73  ? 761 TYR A CD2 1 
ATOM 4658 C CE1 . TYR A 1 591 ? 164.104 168.426 161.380 1.00 68.06  ? 761 TYR A CE1 1 
ATOM 4659 C CE2 . TYR A 1 591 ? 166.204 168.771 160.263 1.00 68.17  ? 761 TYR A CE2 1 
ATOM 4660 C CZ  . TYR A 1 591 ? 165.486 168.306 161.350 1.00 69.14  ? 761 TYR A CZ  1 
ATOM 4661 O OH  . TYR A 1 591 ? 166.151 167.736 162.410 1.00 69.07  ? 761 TYR A OH  1 
ATOM 4662 N N   . SER A 1 592 ? 160.637 171.345 158.361 1.00 70.15  ? 762 SER A N   1 
ATOM 4663 C CA  . SER A 1 592 ? 159.371 171.584 159.044 1.00 69.86  ? 762 SER A CA  1 
ATOM 4664 C C   . SER A 1 592 ? 159.215 170.784 160.319 1.00 69.86  ? 762 SER A C   1 
ATOM 4665 O O   . SER A 1 592 ? 159.939 169.817 160.539 1.00 69.73  ? 762 SER A O   1 
ATOM 4666 C CB  . SER A 1 592 ? 158.197 171.301 158.109 1.00 69.43  ? 762 SER A CB  1 
ATOM 4667 O OG  . SER A 1 592 ? 158.022 169.909 157.941 1.00 69.66  ? 762 SER A OG  1 
ATOM 4668 N N   . TYR A 1 593 ? 158.257 171.206 161.144 1.00 69.70  ? 763 TYR A N   1 
ATOM 4669 C CA  . TYR A 1 593 ? 157.918 170.530 162.392 1.00 69.41  ? 763 TYR A CA  1 
ATOM 4670 C C   . TYR A 1 593 ? 156.454 170.793 162.647 1.00 69.98  ? 763 TYR A C   1 
ATOM 4671 O O   . TYR A 1 593 ? 155.901 171.753 162.099 1.00 70.93  ? 763 TYR A O   1 
ATOM 4672 C CB  . TYR A 1 593 ? 158.758 170.993 163.572 1.00 68.51  ? 763 TYR A CB  1 
ATOM 4673 C CG  . TYR A 1 593 ? 158.573 172.434 163.998 1.00 67.66  ? 763 TYR A CG  1 
ATOM 4674 C CD1 . TYR A 1 593 ? 157.538 172.808 164.854 1.00 65.74  ? 763 TYR A CD1 1 
ATOM 4675 C CD2 . TYR A 1 593 ? 159.462 173.426 163.568 1.00 66.65  ? 763 TYR A CD2 1 
ATOM 4676 C CE1 . TYR A 1 593 ? 157.389 174.138 165.266 1.00 65.59  ? 763 TYR A CE1 1 
ATOM 4677 C CE2 . TYR A 1 593 ? 159.315 174.759 163.963 1.00 65.14  ? 763 TYR A CE2 1 
ATOM 4678 C CZ  . TYR A 1 593 ? 158.285 175.107 164.820 1.00 66.90  ? 763 TYR A CZ  1 
ATOM 4679 O OH  . TYR A 1 593 ? 158.138 176.430 165.217 1.00 66.91  ? 763 TYR A OH  1 
ATOM 4680 N N   . VAL A 1 594 ? 155.810 169.945 163.445 1.00 70.08  ? 764 VAL A N   1 
ATOM 4681 C CA  . VAL A 1 594 ? 154.402 170.140 163.710 1.00 70.12  ? 764 VAL A CA  1 
ATOM 4682 C C   . VAL A 1 594 ? 154.281 171.106 164.850 1.00 69.78  ? 764 VAL A C   1 
ATOM 4683 O O   . VAL A 1 594 ? 154.424 170.733 166.024 1.00 69.77  ? 764 VAL A O   1 
ATOM 4684 C CB  . VAL A 1 594 ? 153.655 168.823 163.998 1.00 70.87  ? 764 VAL A CB  1 
ATOM 4685 C CG1 . VAL A 1 594 ? 152.128 169.054 163.990 1.00 70.47  ? 764 VAL A CG1 1 
ATOM 4686 C CG2 . VAL A 1 594 ? 154.018 167.790 162.946 1.00 72.73  ? 764 VAL A CG2 1 
ATOM 4687 N N   . ALA A 1 595 ? 154.034 172.360 164.491 1.00 69.22  ? 765 ALA A N   1 
ATOM 4688 C CA  . ALA A 1 595 ? 153.884 173.423 165.474 1.00 68.92  ? 765 ALA A CA  1 
ATOM 4689 C C   . ALA A 1 595 ? 152.593 173.299 166.261 1.00 69.00  ? 765 ALA A C   1 
ATOM 4690 O O   . ALA A 1 595 ? 151.604 172.720 165.791 1.00 68.04  ? 765 ALA A O   1 
ATOM 4691 C CB  . ALA A 1 595 ? 153.920 174.763 164.793 1.00 68.63  ? 765 ALA A CB  1 
ATOM 4692 N N   . ALA A 1 596 ? 152.613 173.864 167.466 1.00 69.55  ? 766 ALA A N   1 
ATOM 4693 C CA  . ALA A 1 596 ? 151.436 173.888 168.315 1.00 69.71  ? 766 ALA A CA  1 
ATOM 4694 C C   . ALA A 1 596 ? 150.434 174.720 167.519 1.00 69.88  ? 766 ALA A C   1 
ATOM 4695 O O   . ALA A 1 596 ? 150.764 175.820 167.083 1.00 70.34  ? 766 ALA A O   1 
ATOM 4696 C CB  . ALA A 1 596 ? 151.757 174.561 169.636 1.00 69.37  ? 766 ALA A CB  1 
ATOM 4697 N N   . GLY A 1 597 ? 149.240 174.183 167.297 1.00 70.25  ? 767 GLY A N   1 
ATOM 4698 C CA  . GLY A 1 597 ? 148.203 174.880 166.541 1.00 70.50  ? 767 GLY A CA  1 
ATOM 4699 C C   . GLY A 1 597 ? 148.084 174.313 165.145 1.00 71.05  ? 767 GLY A C   1 
ATOM 4700 O O   . GLY A 1 597 ? 147.194 174.681 164.388 1.00 71.76  ? 767 GLY A O   1 
ATOM 4701 N N   . SER A 1 598 ? 149.000 173.426 164.801 1.00 71.12  ? 768 SER A N   1 
ATOM 4702 C CA  . SER A 1 598 ? 149.016 172.792 163.504 1.00 71.55  ? 768 SER A CA  1 
ATOM 4703 C C   . SER A 1 598 ? 148.655 171.316 163.710 1.00 72.03  ? 768 SER A C   1 
ATOM 4704 O O   . SER A 1 598 ? 148.248 170.920 164.811 1.00 72.46  ? 768 SER A O   1 
ATOM 4705 C CB  . SER A 1 598 ? 150.404 172.940 162.881 1.00 71.75  ? 768 SER A CB  1 
ATOM 4706 O OG  . SER A 1 598 ? 150.455 172.384 161.580 1.00 73.03  ? 768 SER A OG  1 
ATOM 4707 N N   . SER A 1 599 ? 148.796 170.511 162.658 1.00 72.00  ? 769 SER A N   1 
ATOM 4708 C CA  . SER A 1 599 ? 148.486 169.087 162.697 1.00 72.05  ? 769 SER A CA  1 
ATOM 4709 C C   . SER A 1 599 ? 148.918 168.478 161.374 1.00 72.60  ? 769 SER A C   1 
ATOM 4710 O O   . SER A 1 599 ? 149.266 169.196 160.441 1.00 73.08  ? 769 SER A O   1 
ATOM 4711 C CB  . SER A 1 599 ? 146.985 168.860 162.909 1.00 71.82  ? 769 SER A CB  1 
ATOM 4712 O OG  . SER A 1 599 ? 146.274 168.894 161.682 1.00 71.56  ? 769 SER A OG  1 
ATOM 4713 N N   . GLY A 1 600 ? 148.887 167.155 161.280 1.00 72.80  ? 770 GLY A N   1 
ATOM 4714 C CA  . GLY A 1 600 ? 149.261 166.488 160.042 1.00 73.13  ? 770 GLY A CA  1 
ATOM 4715 C C   . GLY A 1 600 ? 148.378 166.911 158.876 1.00 73.70  ? 770 GLY A C   1 
ATOM 4716 O O   . GLY A 1 600 ? 148.780 166.801 157.722 1.00 74.01  ? 770 GLY A O   1 
ATOM 4717 N N   . ASN A 1 601 ? 147.181 167.418 159.151 1.00 73.79  ? 771 ASN A N   1 
ATOM 4718 C CA  . ASN A 1 601 ? 146.309 167.830 158.060 1.00 73.83  ? 771 ASN A CA  1 
ATOM 4719 C C   . ASN A 1 601 ? 146.889 168.970 157.233 1.00 73.19  ? 771 ASN A C   1 
ATOM 4720 O O   . ASN A 1 601 ? 146.636 169.039 156.031 1.00 72.82  ? 771 ASN A O   1 
ATOM 4721 C CB  . ASN A 1 601 ? 144.878 168.105 158.523 1.00 74.37  ? 771 ASN A CB  1 
ATOM 4722 C CG  . ASN A 1 601 ? 143.948 168.425 157.355 1.00 79.36  ? 771 ASN A CG  1 
ATOM 4723 O OD1 . ASN A 1 601 ? 143.476 169.569 157.220 1.00 83.55  ? 771 ASN A OD1 1 
ATOM 4724 N ND2 . ASN A 1 601 ? 143.719 167.430 156.463 1.00 82.48  ? 771 ASN A ND2 1 
ATOM 4725 N N   . ASP A 1 602 ? 147.718 169.820 157.854 1.00 72.65  ? 772 ASP A N   1 
ATOM 4726 C CA  . ASP A 1 602 ? 148.354 170.933 157.153 1.00 71.99  ? 772 ASP A CA  1 
ATOM 4727 C C   . ASP A 1 602 ? 149.328 170.445 156.086 1.00 72.20  ? 772 ASP A C   1 
ATOM 4728 O O   . ASP A 1 602 ? 149.535 171.127 155.071 1.00 72.13  ? 772 ASP A O   1 
ATOM 4729 C CB  . ASP A 1 602 ? 149.067 171.861 158.129 1.00 72.12  ? 772 ASP A CB  1 
ATOM 4730 C CG  . ASP A 1 602 ? 148.106 172.740 158.912 1.00 72.47  ? 772 ASP A CG  1 
ATOM 4731 O OD1 . ASP A 1 602 ? 146.987 173.005 158.433 1.00 71.41  ? 772 ASP A OD1 1 
ATOM 4732 O OD2 . ASP A 1 602 ? 148.481 173.189 160.012 1.00 74.26  ? 772 ASP A OD2 1 
ATOM 4733 N N   . TYR A 1 603 ? 149.922 169.269 156.301 1.00 72.24  ? 773 TYR A N   1 
ATOM 4734 C CA  . TYR A 1 603 ? 150.838 168.713 155.310 1.00 72.69  ? 773 TYR A CA  1 
ATOM 4735 C C   . TYR A 1 603 ? 150.032 168.317 154.069 1.00 72.60  ? 773 TYR A C   1 
ATOM 4736 O O   . TYR A 1 603 ? 150.521 168.465 152.941 1.00 72.34  ? 773 TYR A O   1 
ATOM 4737 C CB  . TYR A 1 603 ? 151.621 167.527 155.845 1.00 73.53  ? 773 TYR A CB  1 
ATOM 4738 C CG  . TYR A 1 603 ? 152.652 167.900 156.870 1.00 74.71  ? 773 TYR A CG  1 
ATOM 4739 C CD1 . TYR A 1 603 ? 153.924 168.284 156.498 1.00 75.75  ? 773 TYR A CD1 1 
ATOM 4740 C CD2 . TYR A 1 603 ? 152.353 167.873 158.218 1.00 76.41  ? 773 TYR A CD2 1 
ATOM 4741 C CE1 . TYR A 1 603 ? 154.882 168.631 157.448 1.00 76.54  ? 773 TYR A CE1 1 
ATOM 4742 C CE2 . TYR A 1 603 ? 153.298 168.221 159.177 1.00 77.82  ? 773 TYR A CE2 1 
ATOM 4743 C CZ  . TYR A 1 603 ? 154.558 168.603 158.788 1.00 77.47  ? 773 TYR A CZ  1 
ATOM 4744 O OH  . TYR A 1 603 ? 155.502 168.941 159.761 1.00 79.36  ? 773 TYR A OH  1 
ATOM 4745 N N   . ASP A 1 604 ? 148.792 167.858 154.283 1.00 71.77  ? 774 ASP A N   1 
ATOM 4746 C CA  . ASP A 1 604 ? 147.913 167.497 153.193 1.00 71.62  ? 774 ASP A CA  1 
ATOM 4747 C C   . ASP A 1 604 ? 147.531 168.759 152.427 1.00 71.21  ? 774 ASP A C   1 
ATOM 4748 O O   . ASP A 1 604 ? 147.557 168.782 151.191 1.00 71.06  ? 774 ASP A O   1 
ATOM 4749 C CB  . ASP A 1 604 ? 146.670 166.798 153.705 1.00 72.04  ? 774 ASP A CB  1 
ATOM 4750 C CG  . ASP A 1 604 ? 146.921 165.339 154.038 1.00 74.48  ? 774 ASP A CG  1 
ATOM 4751 O OD1 . ASP A 1 604 ? 147.884 164.768 153.473 1.00 77.03  ? 774 ASP A OD1 1 
ATOM 4752 O OD2 . ASP A 1 604 ? 146.163 164.769 154.872 1.00 75.73  ? 774 ASP A OD2 1 
ATOM 4753 N N   . LEU A 1 605 ? 147.204 169.816 153.159 1.00 70.74  ? 775 LEU A N   1 
ATOM 4754 C CA  . LEU A 1 605 ? 146.858 171.072 152.532 1.00 70.43  ? 775 LEU A CA  1 
ATOM 4755 C C   . LEU A 1 605 ? 148.047 171.571 151.724 1.00 70.91  ? 775 LEU A C   1 
ATOM 4756 O O   . LEU A 1 605 ? 147.864 172.031 150.589 1.00 71.15  ? 775 LEU A O   1 
ATOM 4757 C CB  . LEU A 1 605 ? 146.402 172.110 153.551 1.00 70.11  ? 775 LEU A CB  1 
ATOM 4758 C CG  . LEU A 1 605 ? 145.061 171.795 154.234 1.00 68.99  ? 775 LEU A CG  1 
ATOM 4759 C CD1 . LEU A 1 605 ? 144.823 172.746 155.399 1.00 67.96  ? 775 LEU A CD1 1 
ATOM 4760 C CD2 . LEU A 1 605 ? 143.887 171.818 153.260 1.00 64.72  ? 775 LEU A CD2 1 
ATOM 4761 N N   . MET A 1 606 ? 149.267 171.451 152.256 1.00 70.96  ? 776 MET A N   1 
ATOM 4762 C CA  . MET A 1 606 ? 150.431 171.907 151.481 1.00 71.65  ? 776 MET A CA  1 
ATOM 4763 C C   . MET A 1 606 ? 150.525 171.159 150.165 1.00 71.16  ? 776 MET A C   1 
ATOM 4764 O O   . MET A 1 606 ? 150.956 171.721 149.171 1.00 71.89  ? 776 MET A O   1 
ATOM 4765 C CB  . MET A 1 606 ? 151.750 171.705 152.218 1.00 72.38  ? 776 MET A CB  1 
ATOM 4766 C CG  . MET A 1 606 ? 151.997 172.617 153.395 1.00 75.58  ? 776 MET A CG  1 
ATOM 4767 S SD  . MET A 1 606 ? 151.749 174.313 152.946 1.00 83.58  ? 776 MET A SD  1 
ATOM 4768 C CE  . MET A 1 606 ? 152.938 174.511 151.615 1.00 83.05  ? 776 MET A CE  1 
ATOM 4769 N N   . ALA A 1 607 ? 150.120 169.894 150.169 1.00 70.31  ? 777 ALA A N   1 
ATOM 4770 C CA  . ALA A 1 607 ? 150.167 169.066 148.983 1.00 70.16  ? 777 ALA A CA  1 
ATOM 4771 C C   . ALA A 1 607 ? 149.104 169.321 147.893 1.00 70.54  ? 777 ALA A C   1 
ATOM 4772 O O   . ALA A 1 607 ? 149.351 168.957 146.752 1.00 70.37  ? 777 ALA A O   1 
ATOM 4773 C CB  . ALA A 1 607 ? 150.162 167.600 149.373 1.00 69.76  ? 777 ALA A CB  1 
ATOM 4774 N N   . GLN A 1 608 ? 147.955 169.896 148.221 1.00 70.79  ? 778 GLN A N   1 
ATOM 4775 C CA  . GLN A 1 608 ? 146.919 170.114 147.208 1.00 72.13  ? 778 GLN A CA  1 
ATOM 4776 C C   . GLN A 1 608 ? 147.244 171.103 146.082 1.00 72.12  ? 778 GLN A C   1 
ATOM 4777 O O   . GLN A 1 608 ? 147.536 172.271 146.344 1.00 72.70  ? 778 GLN A O   1 
ATOM 4778 C CB  . GLN A 1 608 ? 145.591 170.489 147.870 1.00 72.27  ? 778 GLN A CB  1 
ATOM 4779 C CG  . GLN A 1 608 ? 144.995 169.387 148.731 1.00 78.39  ? 778 GLN A CG  1 
ATOM 4780 C CD  . GLN A 1 608 ? 145.103 168.020 148.085 1.00 85.04  ? 778 GLN A CD  1 
ATOM 4781 O OE1 . GLN A 1 608 ? 144.463 167.747 147.070 1.00 86.37  ? 778 GLN A OE1 1 
ATOM 4782 N NE2 . GLN A 1 608 ? 145.917 167.152 148.674 1.00 83.59  ? 778 GLN A NE2 1 
ATOM 4783 N N   . PRO A 1 609 ? 147.172 170.642 144.831 1.00 71.73  ? 779 PRO A N   1 
ATOM 4784 C CA  . PRO A 1 609 ? 147.422 171.513 143.697 1.00 71.66  ? 779 PRO A CA  1 
ATOM 4785 C C   . PRO A 1 609 ? 146.410 172.645 143.647 1.00 71.91  ? 779 PRO A C   1 
ATOM 4786 O O   . PRO A 1 609 ? 145.335 172.511 144.224 1.00 72.34  ? 779 PRO A O   1 
ATOM 4787 C CB  . PRO A 1 609 ? 147.199 170.592 142.503 1.00 71.95  ? 779 PRO A CB  1 
ATOM 4788 C CG  . PRO A 1 609 ? 146.284 169.526 143.018 1.00 70.99  ? 779 PRO A CG  1 
ATOM 4789 C CD  . PRO A 1 609 ? 146.752 169.294 144.402 1.00 71.61  ? 779 PRO A CD  1 
ATOM 4790 N N   . ILE A 1 610 ? 146.759 173.731 142.963 1.00 71.80  ? 780 ILE A N   1 
ATOM 4791 C CA  . ILE A 1 610 ? 145.900 174.893 142.801 1.00 72.22  ? 780 ILE A CA  1 
ATOM 4792 C C   . ILE A 1 610 ? 145.345 174.904 141.369 1.00 72.67  ? 780 ILE A C   1 
ATOM 4793 O O   . ILE A 1 610 ? 146.054 174.603 140.407 1.00 72.23  ? 780 ILE A O   1 
ATOM 4794 C CB  . ILE A 1 610 ? 146.692 176.211 143.025 1.00 72.83  ? 780 ILE A CB  1 
ATOM 4795 C CG1 . ILE A 1 610 ? 147.434 176.191 144.373 1.00 72.82  ? 780 ILE A CG1 1 
ATOM 4796 C CG2 . ILE A 1 610 ? 145.791 177.451 142.871 1.00 71.21  ? 780 ILE A CG2 1 
ATOM 4797 C CD1 . ILE A 1 610 ? 146.526 176.199 145.561 1.00 73.54  ? 780 ILE A CD1 1 
ATOM 4798 N N   . THR A 1 611 ? 144.063 175.238 141.243 1.00 73.13  ? 781 THR A N   1 
ATOM 4799 C CA  . THR A 1 611 ? 143.381 175.299 139.962 1.00 73.50  ? 781 THR A CA  1 
ATOM 4800 C C   . THR A 1 611 ? 142.951 176.740 139.748 1.00 73.65  ? 781 THR A C   1 
ATOM 4801 O O   . THR A 1 611 ? 142.118 177.239 140.503 1.00 74.68  ? 781 THR A O   1 
ATOM 4802 C CB  . THR A 1 611 ? 142.136 174.393 139.966 1.00 73.18  ? 781 THR A CB  1 
ATOM 4803 O OG1 . THR A 1 611 ? 142.552 173.024 139.971 1.00 74.86  ? 781 THR A OG1 1 
ATOM 4804 C CG2 . THR A 1 611 ? 141.289 174.616 138.738 1.00 73.27  ? 781 THR A CG2 1 
ATOM 4805 N N   . PRO A 1 612 ? 143.491 177.413 138.715 1.00 73.19  ? 782 PRO A N   1 
ATOM 4806 C CA  . PRO A 1 612 ? 143.112 178.809 138.467 1.00 73.14  ? 782 PRO A CA  1 
ATOM 4807 C C   . PRO A 1 612 ? 141.670 178.914 138.023 1.00 73.28  ? 782 PRO A C   1 
ATOM 4808 O O   . PRO A 1 612 ? 141.102 177.919 137.566 1.00 73.70  ? 782 PRO A O   1 
ATOM 4809 C CB  . PRO A 1 612 ? 144.000 179.212 137.296 1.00 72.58  ? 782 PRO A CB  1 
ATOM 4810 C CG  . PRO A 1 612 ? 144.325 177.956 136.623 1.00 73.24  ? 782 PRO A CG  1 
ATOM 4811 C CD  . PRO A 1 612 ? 144.437 176.919 137.707 1.00 72.78  ? 782 PRO A CD  1 
ATOM 4812 N N   . GLY A 1 613 ? 141.084 180.103 138.141 1.00 73.43  ? 783 GLY A N   1 
ATOM 4813 C CA  . GLY A 1 613 ? 139.702 180.315 137.701 1.00 73.62  ? 783 GLY A CA  1 
ATOM 4814 C C   . GLY A 1 613 ? 139.708 180.456 136.182 1.00 73.80  ? 783 GLY A C   1 
ATOM 4815 O O   . GLY A 1 613 ? 140.777 180.554 135.581 1.00 73.82  ? 783 GLY A O   1 
ATOM 4816 N N   . PRO A 1 614 ? 138.529 180.455 135.542 1.00 74.06  ? 784 PRO A N   1 
ATOM 4817 C CA  . PRO A 1 614 ? 138.537 180.609 134.084 1.00 74.79  ? 784 PRO A CA  1 
ATOM 4818 C C   . PRO A 1 614 ? 138.942 182.014 133.661 1.00 76.22  ? 784 PRO A C   1 
ATOM 4819 O O   . PRO A 1 614 ? 138.793 182.958 134.443 1.00 76.19  ? 784 PRO A O   1 
ATOM 4820 C CB  . PRO A 1 614 ? 137.082 180.356 133.693 1.00 74.63  ? 784 PRO A CB  1 
ATOM 4821 C CG  . PRO A 1 614 ? 136.296 180.656 134.925 1.00 74.17  ? 784 PRO A CG  1 
ATOM 4822 C CD  . PRO A 1 614 ? 137.172 180.298 136.088 1.00 73.73  ? 784 PRO A CD  1 
ATOM 4823 N N   . SER A 1 615 ? 139.455 182.145 132.436 1.00 77.82  ? 785 SER A N   1 
ATOM 4824 C CA  . SER A 1 615 ? 139.856 183.448 131.893 1.00 79.21  ? 785 SER A CA  1 
ATOM 4825 C C   . SER A 1 615 ? 138.601 184.122 131.391 1.00 80.07  ? 785 SER A C   1 
ATOM 4826 O O   . SER A 1 615 ? 138.424 185.327 131.538 1.00 80.45  ? 785 SER A O   1 
ATOM 4827 C CB  . SER A 1 615 ? 140.829 183.296 130.714 1.00 79.21  ? 785 SER A CB  1 
ATOM 4828 O OG  . SER A 1 615 ? 142.108 182.849 131.131 1.00 80.60  ? 785 SER A OG  1 
ATOM 4829 N N   . ILE A 1 616 ? 137.730 183.322 130.790 1.00 81.12  ? 786 ILE A N   1 
ATOM 4830 C CA  . ILE A 1 616 ? 136.484 183.816 130.242 1.00 82.36  ? 786 ILE A CA  1 
ATOM 4831 C C   . ILE A 1 616 ? 135.336 183.476 131.195 1.00 82.52  ? 786 ILE A C   1 
ATOM 4832 O O   . ILE A 1 616 ? 135.172 182.323 131.565 1.00 82.91  ? 786 ILE A O   1 
ATOM 4833 C CB  . ILE A 1 616 ? 136.255 183.222 128.815 1.00 82.80  ? 786 ILE A CB  1 
ATOM 4834 C CG1 . ILE A 1 616 ? 137.422 183.617 127.888 1.00 84.11  ? 786 ILE A CG1 1 
ATOM 4835 C CG2 . ILE A 1 616 ? 134.925 183.679 128.218 1.00 82.46  ? 786 ILE A CG2 1 
ATOM 4836 C CD1 . ILE A 1 616 ? 137.938 182.480 126.985 1.00 86.13  ? 786 ILE A CD1 1 
ATOM 4837 N N   . PRO A 1 617 ? 134.556 184.488 131.617 1.00 82.81  ? 787 PRO A N   1 
ATOM 4838 C CA  . PRO A 1 617 ? 133.282 184.253 132.314 1.00 82.86  ? 787 PRO A CA  1 
ATOM 4839 C C   . PRO A 1 617 ? 132.434 183.162 131.644 1.00 82.57  ? 787 PRO A C   1 
ATOM 4840 O O   . PRO A 1 617 ? 132.184 183.223 130.432 1.00 82.11  ? 787 PRO A O   1 
ATOM 4841 C CB  . PRO A 1 617 ? 132.550 185.608 132.184 1.00 83.16  ? 787 PRO A CB  1 
ATOM 4842 C CG  . PRO A 1 617 ? 133.416 186.454 131.232 1.00 83.04  ? 787 PRO A CG  1 
ATOM 4843 C CD  . PRO A 1 617 ? 134.806 185.927 131.453 1.00 82.78  ? 787 PRO A CD  1 
ATOM 4844 N N   . GLY A 1 618 ? 132.018 182.174 132.434 1.00 82.35  ? 788 GLY A N   1 
ATOM 4845 C CA  . GLY A 1 618 ? 131.194 181.072 131.941 1.00 81.98  ? 788 GLY A CA  1 
ATOM 4846 C C   . GLY A 1 618 ? 131.930 179.917 131.282 1.00 81.68  ? 788 GLY A C   1 
ATOM 4847 O O   . GLY A 1 618 ? 131.298 178.981 130.784 1.00 81.45  ? 788 GLY A O   1 
ATOM 4848 N N   . ALA A 1 619 ? 133.260 179.974 131.266 1.00 81.21  ? 789 ALA A N   1 
ATOM 4849 C CA  . ALA A 1 619 ? 134.037 178.918 130.655 1.00 81.20  ? 789 ALA A CA  1 
ATOM 4850 C C   . ALA A 1 619 ? 134.279 177.820 131.684 1.00 81.77  ? 789 ALA A C   1 
ATOM 4851 O O   . ALA A 1 619 ? 134.486 178.111 132.864 1.00 81.89  ? 789 ALA A O   1 
ATOM 4852 C CB  . ALA A 1 619 ? 135.332 179.450 130.115 1.00 80.81  ? 789 ALA A CB  1 
ATOM 4853 N N   . PRO A 1 620 ? 134.238 176.550 131.241 1.00 82.06  ? 790 PRO A N   1 
ATOM 4854 C CA  . PRO A 1 620 ? 134.371 175.408 132.116 1.00 82.24  ? 790 PRO A CA  1 
ATOM 4855 C C   . PRO A 1 620 ? 135.606 175.429 133.005 1.00 82.89  ? 790 PRO A C   1 
ATOM 4856 O O   . PRO A 1 620 ? 136.639 176.014 132.658 1.00 82.55  ? 790 PRO A O   1 
ATOM 4857 C CB  . PRO A 1 620 ? 134.451 174.229 131.144 1.00 82.32  ? 790 PRO A CB  1 
ATOM 4858 C CG  . PRO A 1 620 ? 134.758 174.835 129.818 1.00 82.31  ? 790 PRO A CG  1 
ATOM 4859 C CD  . PRO A 1 620 ? 134.048 176.122 129.847 1.00 82.00  ? 790 PRO A CD  1 
ATOM 4860 N N   . GLN A 1 621 ? 135.448 174.750 134.142 1.00 83.51  ? 791 GLN A N   1 
ATOM 4861 C CA  . GLN A 1 621 ? 136.440 174.582 135.197 1.00 84.22  ? 791 GLN A CA  1 
ATOM 4862 C C   . GLN A 1 621 ? 137.834 174.070 134.709 1.00 83.62  ? 791 GLN A C   1 
ATOM 4863 O O   . GLN A 1 621 ? 137.983 172.936 134.237 1.00 84.01  ? 791 GLN A O   1 
ATOM 4864 C CB  . GLN A 1 621 ? 135.798 173.695 136.295 1.00 84.52  ? 791 GLN A CB  1 
ATOM 4865 C CG  . GLN A 1 621 ? 136.737 173.067 137.348 1.00 87.40  ? 791 GLN A CG  1 
ATOM 4866 C CD  . GLN A 1 621 ? 137.028 173.989 138.517 1.00 91.52  ? 791 GLN A CD  1 
ATOM 4867 O OE1 . GLN A 1 621 ? 137.539 175.101 138.337 1.00 94.44  ? 791 GLN A OE1 1 
ATOM 4868 N NE2 . GLN A 1 621 ? 136.735 173.521 139.730 1.00 93.68  ? 791 GLN A NE2 1 
ATOM 4869 N N   . PRO A 1 622 ? 138.855 174.926 134.790 1.00 83.18  ? 792 PRO A N   1 
ATOM 4870 C CA  . PRO A 1 622 ? 140.157 174.444 134.318 1.00 82.79  ? 792 PRO A CA  1 
ATOM 4871 C C   . PRO A 1 622 ? 140.755 173.201 135.003 1.00 82.17  ? 792 PRO A C   1 
ATOM 4872 O O   . PRO A 1 622 ? 140.202 172.617 135.927 1.00 82.58  ? 792 PRO A O   1 
ATOM 4873 C CB  . PRO A 1 622 ? 141.094 175.666 134.498 1.00 82.11  ? 792 PRO A CB  1 
ATOM 4874 C CG  . PRO A 1 622 ? 140.174 176.832 134.537 1.00 82.65  ? 792 PRO A CG  1 
ATOM 4875 C CD  . PRO A 1 622 ? 138.906 176.344 135.194 1.00 83.30  ? 792 PRO A CD  1 
ATOM 4876 N N   . ILE A 1 623 ? 141.905 172.846 134.448 1.00 81.06  ? 793 ILE A N   1 
ATOM 4877 C CA  . ILE A 1 623 ? 142.818 171.796 134.776 1.00 78.70  ? 793 ILE A CA  1 
ATOM 4878 C C   . ILE A 1 623 ? 143.593 172.398 135.963 1.00 76.74  ? 793 ILE A C   1 
ATOM 4879 O O   . ILE A 1 623 ? 143.674 173.608 136.078 1.00 76.09  ? 793 ILE A O   1 
ATOM 4880 C CB  . ILE A 1 623 ? 143.732 171.704 133.498 1.00 78.90  ? 793 ILE A CB  1 
ATOM 4881 C CG1 . ILE A 1 623 ? 142.939 171.167 132.298 1.00 80.36  ? 793 ILE A CG1 1 
ATOM 4882 C CG2 . ILE A 1 623 ? 144.972 170.920 133.688 1.00 80.34  ? 793 ILE A CG2 1 
ATOM 4883 C CD1 . ILE A 1 623 ? 142.489 172.272 131.293 1.00 81.21  ? 793 ILE A CD1 1 
ATOM 4884 N N   . PRO A 1 624 ? 144.136 171.573 136.882 1.00 75.35  ? 794 PRO A N   1 
ATOM 4885 C CA  . PRO A 1 624 ? 145.026 172.155 137.892 1.00 73.85  ? 794 PRO A CA  1 
ATOM 4886 C C   . PRO A 1 624 ? 146.327 172.567 137.226 1.00 72.49  ? 794 PRO A C   1 
ATOM 4887 O O   . PRO A 1 624 ? 146.776 171.884 136.301 1.00 71.98  ? 794 PRO A O   1 
ATOM 4888 C CB  . PRO A 1 624 ? 145.253 170.998 138.874 1.00 73.60  ? 794 PRO A CB  1 
ATOM 4889 C CG  . PRO A 1 624 ? 144.168 170.027 138.557 1.00 74.72  ? 794 PRO A CG  1 
ATOM 4890 C CD  . PRO A 1 624 ? 143.961 170.130 137.100 1.00 75.12  ? 794 PRO A CD  1 
ATOM 4891 N N   . ARG A 1 625 ? 146.921 173.668 137.680 1.00 71.13  ? 795 ARG A N   1 
ATOM 4892 C CA  . ARG A 1 625 ? 148.146 174.158 137.073 1.00 70.22  ? 795 ARG A CA  1 
ATOM 4893 C C   . ARG A 1 625 ? 149.369 174.273 137.962 1.00 70.32  ? 795 ARG A C   1 
ATOM 4894 O O   . ARG A 1 625 ? 150.495 174.199 137.451 1.00 70.64  ? 795 ARG A O   1 
ATOM 4895 C CB  . ARG A 1 625 ? 147.893 175.534 136.457 1.00 70.29  ? 795 ARG A CB  1 
ATOM 4896 C CG  . ARG A 1 625 ? 146.900 175.553 135.302 1.00 69.03  ? 795 ARG A CG  1 
ATOM 4897 C CD  . ARG A 1 625 ? 147.508 175.111 133.985 1.00 68.23  ? 795 ARG A CD  1 
ATOM 4898 N NE  . ARG A 1 625 ? 146.503 175.165 132.927 1.00 68.73  ? 795 ARG A NE  1 
ATOM 4899 C CZ  . ARG A 1 625 ? 146.627 174.637 131.715 1.00 67.32  ? 795 ARG A CZ  1 
ATOM 4900 N NH1 . ARG A 1 625 ? 147.731 173.995 131.355 1.00 66.14  ? 795 ARG A NH1 1 
ATOM 4901 N NH2 . ARG A 1 625 ? 145.623 174.751 130.861 1.00 66.10  ? 795 ARG A NH2 1 
ATOM 4902 N N   . LEU A 1 626 ? 149.157 174.500 139.261 1.00 69.53  ? 796 LEU A N   1 
ATOM 4903 C CA  . LEU A 1 626 ? 150.237 174.691 140.215 1.00 69.14  ? 796 LEU A CA  1 
ATOM 4904 C C   . LEU A 1 626 ? 150.286 173.562 141.228 1.00 69.32  ? 796 LEU A C   1 
ATOM 4905 O O   . LEU A 1 626 ? 149.331 173.334 141.959 1.00 69.85  ? 796 LEU A O   1 
ATOM 4906 C CB  . LEU A 1 626 ? 150.078 176.050 140.900 1.00 69.25  ? 796 LEU A CB  1 
ATOM 4907 C CG  . LEU A 1 626 ? 151.096 176.517 141.954 1.00 69.07  ? 796 LEU A CG  1 
ATOM 4908 C CD1 . LEU A 1 626 ? 152.554 176.394 141.482 1.00 66.49  ? 796 LEU A CD1 1 
ATOM 4909 C CD2 . LEU A 1 626 ? 150.762 177.964 142.287 1.00 68.51  ? 796 LEU A CD2 1 
ATOM 4910 N N   . PHE A 1 627 ? 151.404 172.846 141.251 1.00 68.82  ? 797 PHE A N   1 
ATOM 4911 C CA  . PHE A 1 627 ? 151.558 171.697 142.107 1.00 67.91  ? 797 PHE A CA  1 
ATOM 4912 C C   . PHE A 1 627 ? 152.631 171.923 143.150 1.00 68.48  ? 797 PHE A C   1 
ATOM 4913 O O   . PHE A 1 627 ? 153.504 172.785 142.970 1.00 69.27  ? 797 PHE A O   1 
ATOM 4914 C CB  . PHE A 1 627 ? 151.883 170.482 141.227 1.00 67.38  ? 797 PHE A CB  1 
ATOM 4915 C CG  . PHE A 1 627 ? 150.829 170.186 140.179 1.00 66.54  ? 797 PHE A CG  1 
ATOM 4916 C CD1 . PHE A 1 627 ? 150.708 170.981 139.025 1.00 64.05  ? 797 PHE A CD1 1 
ATOM 4917 C CD2 . PHE A 1 627 ? 149.951 169.126 140.347 1.00 65.29  ? 797 PHE A CD2 1 
ATOM 4918 C CE1 . PHE A 1 627 ? 149.731 170.723 138.074 1.00 62.93  ? 797 PHE A CE1 1 
ATOM 4919 C CE2 . PHE A 1 627 ? 148.973 168.853 139.383 1.00 65.21  ? 797 PHE A CE2 1 
ATOM 4920 C CZ  . PHE A 1 627 ? 148.865 169.667 138.244 1.00 64.44  ? 797 PHE A CZ  1 
ATOM 4921 N N   . PHE A 1 628 ? 152.580 171.153 144.236 1.00 68.04  ? 798 PHE A N   1 
ATOM 4922 C CA  . PHE A 1 628 ? 153.566 171.307 145.310 1.00 67.97  ? 798 PHE A CA  1 
ATOM 4923 C C   . PHE A 1 628 ? 154.173 170.009 145.775 1.00 67.93  ? 798 PHE A C   1 
ATOM 4924 O O   . PHE A 1 628 ? 153.480 169.000 145.989 1.00 66.77  ? 798 PHE A O   1 
ATOM 4925 C CB  . PHE A 1 628 ? 152.953 171.999 146.530 1.00 67.63  ? 798 PHE A CB  1 
ATOM 4926 C CG  . PHE A 1 628 ? 152.422 173.366 146.235 1.00 68.65  ? 798 PHE A CG  1 
ATOM 4927 C CD1 . PHE A 1 628 ? 151.136 173.533 145.737 1.00 66.53  ? 798 PHE A CD1 1 
ATOM 4928 C CD2 . PHE A 1 628 ? 153.216 174.494 146.448 1.00 69.40  ? 798 PHE A CD2 1 
ATOM 4929 C CE1 . PHE A 1 628 ? 150.652 174.786 145.460 1.00 68.56  ? 798 PHE A CE1 1 
ATOM 4930 C CE2 . PHE A 1 628 ? 152.738 175.765 146.180 1.00 67.70  ? 798 PHE A CE2 1 
ATOM 4931 C CZ  . PHE A 1 628 ? 151.454 175.916 145.679 1.00 67.81  ? 798 PHE A CZ  1 
ATOM 4932 N N   . ALA A 1 629 ? 155.484 170.059 145.949 1.00 67.70  ? 799 ALA A N   1 
ATOM 4933 C CA  . ALA A 1 629 ? 156.211 168.923 146.444 1.00 68.34  ? 799 ALA A CA  1 
ATOM 4934 C C   . ALA A 1 629 ? 157.184 169.490 147.453 1.00 68.77  ? 799 ALA A C   1 
ATOM 4935 O O   . ALA A 1 629 ? 157.292 170.718 147.621 1.00 68.96  ? 799 ALA A O   1 
ATOM 4936 C CB  . ALA A 1 629 ? 156.927 168.190 145.337 1.00 68.11  ? 799 ALA A CB  1 
ATOM 4937 N N   . GLY A 1 630 ? 157.899 168.596 148.112 1.00 68.83  ? 800 GLY A N   1 
ATOM 4938 C CA  . GLY A 1 630 ? 158.829 169.001 149.126 1.00 68.75  ? 800 GLY A CA  1 
ATOM 4939 C C   . GLY A 1 630 ? 158.466 168.332 150.432 1.00 68.85  ? 800 GLY A C   1 
ATOM 4940 O O   . GLY A 1 630 ? 157.332 167.893 150.685 1.00 68.90  ? 800 GLY A O   1 
ATOM 4941 N N   . GLU A 1 631 ? 159.484 168.201 151.290 1.00 69.26  ? 801 GLU A N   1 
ATOM 4942 C CA  . GLU A 1 631 ? 159.283 167.499 152.585 1.00 69.43  ? 801 GLU A CA  1 
ATOM 4943 C C   . GLU A 1 631 ? 158.068 168.084 153.308 1.00 69.74  ? 801 GLU A C   1 
ATOM 4944 O O   . GLU A 1 631 ? 157.333 167.297 153.937 1.00 70.02  ? 801 GLU A O   1 
ATOM 4945 C CB  . GLU A 1 631 ? 160.544 167.591 153.450 1.00 69.28  ? 801 GLU A CB  1 
ATOM 4946 C CG  . GLU A 1 631 ? 160.588 168.809 154.358 1.00 71.14  ? 801 GLU A CG  1 
ATOM 4947 C CD  . GLU A 1 631 ? 160.695 170.154 153.658 1.00 72.12  ? 801 GLU A CD  1 
ATOM 4948 O OE1 . GLU A 1 631 ? 160.826 170.169 152.419 1.00 69.12  ? 801 GLU A OE1 1 
ATOM 4949 O OE2 . GLU A 1 631 ? 160.644 171.185 154.358 1.00 74.71  ? 801 GLU A OE2 1 
ATOM 4950 N N   . HIS A 1 632 ? 157.858 169.402 153.229 1.00 69.57  ? 802 HIS A N   1 
ATOM 4951 C CA  . HIS A 1 632 ? 156.743 169.944 153.992 1.00 69.29  ? 802 HIS A CA  1 
ATOM 4952 C C   . HIS A 1 632 ? 155.366 169.563 153.413 1.00 69.41  ? 802 HIS A C   1 
ATOM 4953 O O   . HIS A 1 632 ? 154.344 170.074 153.892 1.00 68.79  ? 802 HIS A O   1 
ATOM 4954 C CB  . HIS A 1 632 ? 156.866 171.449 153.991 1.00 68.99  ? 802 HIS A CB  1 
ATOM 4955 C CG  . HIS A 1 632 ? 156.913 172.026 152.615 1.00 69.23  ? 802 HIS A CG  1 
ATOM 4956 N ND1 . HIS A 1 632 ? 158.006 171.882 151.789 1.00 70.62  ? 802 HIS A ND1 1 
ATOM 4957 C CD2 . HIS A 1 632 ? 155.997 172.724 151.905 1.00 69.03  ? 802 HIS A CD2 1 
ATOM 4958 C CE1 . HIS A 1 632 ? 157.767 172.475 150.634 1.00 68.35  ? 802 HIS A CE1 1 
ATOM 4959 N NE2 . HIS A 1 632 ? 156.551 172.995 150.679 1.00 67.04  ? 802 HIS A NE2 1 
ATOM 4960 N N   . THR A 1 633 ? 155.336 168.690 152.395 1.00 68.81  ? 803 THR A N   1 
ATOM 4961 C CA  . THR A 1 633 ? 154.078 168.307 151.749 1.00 68.60  ? 803 THR A CA  1 
ATOM 4962 C C   . THR A 1 633 ? 153.717 166.824 151.891 1.00 68.96  ? 803 THR A C   1 
ATOM 4963 O O   . THR A 1 633 ? 152.790 166.345 151.238 1.00 69.01  ? 803 THR A O   1 
ATOM 4964 C CB  . THR A 1 633 ? 154.121 168.621 150.239 1.00 68.86  ? 803 THR A CB  1 
ATOM 4965 O OG1 . THR A 1 633 ? 154.986 167.682 149.576 1.00 68.62  ? 803 THR A OG1 1 
ATOM 4966 C CG2 . THR A 1 633 ? 154.643 170.049 149.979 1.00 68.52  ? 803 THR A CG2 1 
ATOM 4967 N N   . ILE A 1 634 ? 154.449 166.094 152.726 1.00 68.59  ? 804 ILE A N   1 
ATOM 4968 C CA  . ILE A 1 634 ? 154.213 164.678 152.909 1.00 67.94  ? 804 ILE A CA  1 
ATOM 4969 C C   . ILE A 1 634 ? 154.008 164.363 154.404 1.00 68.86  ? 804 ILE A C   1 
ATOM 4970 O O   . ILE A 1 634 ? 154.943 164.313 155.224 1.00 68.89  ? 804 ILE A O   1 
ATOM 4971 C CB  . ILE A 1 634 ? 155.328 163.859 152.225 1.00 67.46  ? 804 ILE A CB  1 
ATOM 4972 C CG1 . ILE A 1 634 ? 155.031 162.358 152.295 1.00 66.69  ? 804 ILE A CG1 1 
ATOM 4973 C CG2 . ILE A 1 634 ? 156.708 164.222 152.786 1.00 66.87  ? 804 ILE A CG2 1 
ATOM 4974 C CD1 . ILE A 1 634 ? 155.830 161.540 151.304 1.00 64.04  ? 804 ILE A CD1 1 
ATOM 4975 N N   . ARG A 1 635 ? 152.740 164.188 154.735 1.00 69.13  ? 805 ARG A N   1 
ATOM 4976 C CA  . ARG A 1 635 ? 152.268 163.929 156.081 1.00 69.20  ? 805 ARG A CA  1 
ATOM 4977 C C   . ARG A 1 635 ? 152.971 162.792 156.834 1.00 69.57  ? 805 ARG A C   1 
ATOM 4978 O O   . ARG A 1 635 ? 153.275 162.920 158.032 1.00 69.18  ? 805 ARG A O   1 
ATOM 4979 C CB  . ARG A 1 635 ? 150.758 163.682 155.975 1.00 69.33  ? 805 ARG A CB  1 
ATOM 4980 C CG  . ARG A 1 635 ? 150.071 163.181 157.200 1.00 69.75  ? 805 ARG A CG  1 
ATOM 4981 C CD  . ARG A 1 635 ? 148.580 163.150 156.999 1.00 69.83  ? 805 ARG A CD  1 
ATOM 4982 N NE  . ARG A 1 635 ? 147.944 163.165 158.306 1.00 71.82  ? 805 ARG A NE  1 
ATOM 4983 C CZ  . ARG A 1 635 ? 146.781 163.741 158.576 1.00 71.51  ? 805 ARG A CZ  1 
ATOM 4984 N NH1 . ARG A 1 635 ? 146.088 164.364 157.620 1.00 71.45  ? 805 ARG A NH1 1 
ATOM 4985 N NH2 . ARG A 1 635 ? 146.322 163.703 159.815 1.00 70.86  ? 805 ARG A NH2 1 
ATOM 4986 N N   . ASN A 1 636 ? 153.227 161.676 156.159 1.00 69.55  ? 806 ASN A N   1 
ATOM 4987 C CA  . ASN A 1 636 ? 153.860 160.547 156.858 1.00 69.78  ? 806 ASN A CA  1 
ATOM 4988 C C   . ASN A 1 636 ? 155.363 160.553 157.028 1.00 69.56  ? 806 ASN A C   1 
ATOM 4989 O O   . ASN A 1 636 ? 155.873 159.856 157.901 1.00 70.52  ? 806 ASN A O   1 
ATOM 4990 C CB  . ASN A 1 636 ? 153.424 159.208 156.257 1.00 69.57  ? 806 ASN A CB  1 
ATOM 4991 C CG  . ASN A 1 636 ? 151.958 158.920 156.494 1.00 70.82  ? 806 ASN A CG  1 
ATOM 4992 O OD1 . ASN A 1 636 ? 151.259 159.688 157.156 1.00 73.81  ? 806 ASN A OD1 1 
ATOM 4993 N ND2 . ASN A 1 636 ? 151.482 157.813 155.959 1.00 72.82  ? 806 ASN A ND2 1 
ATOM 4994 N N   . TYR A 1 637 ? 156.065 161.332 156.214 1.00 69.10  ? 807 TYR A N   1 
ATOM 4995 C CA  . TYR A 1 637 ? 157.523 161.369 156.252 1.00 68.29  ? 807 TYR A CA  1 
ATOM 4996 C C   . TYR A 1 637 ? 158.110 162.769 156.117 1.00 67.86  ? 807 TYR A C   1 
ATOM 4997 O O   . TYR A 1 637 ? 159.083 162.976 155.376 1.00 67.79  ? 807 TYR A O   1 
ATOM 4998 C CB  . TYR A 1 637 ? 158.080 160.479 155.127 1.00 68.10  ? 807 TYR A CB  1 
ATOM 4999 C CG  . TYR A 1 637 ? 157.491 159.101 155.109 1.00 67.72  ? 807 TYR A CG  1 
ATOM 5000 C CD1 . TYR A 1 637 ? 158.019 158.074 155.901 1.00 67.11  ? 807 TYR A CD1 1 
ATOM 5001 C CD2 . TYR A 1 637 ? 156.395 158.818 154.304 1.00 67.50  ? 807 TYR A CD2 1 
ATOM 5002 C CE1 . TYR A 1 637 ? 157.461 156.789 155.880 1.00 67.50  ? 807 TYR A CE1 1 
ATOM 5003 C CE2 . TYR A 1 637 ? 155.829 157.556 154.271 1.00 66.71  ? 807 TYR A CE2 1 
ATOM 5004 C CZ  . TYR A 1 637 ? 156.359 156.544 155.044 1.00 68.69  ? 807 TYR A CZ  1 
ATOM 5005 O OH  . TYR A 1 637 ? 155.746 155.299 154.988 1.00 69.59  ? 807 TYR A OH  1 
ATOM 5006 N N   . PRO A 1 638 ? 157.570 163.731 156.871 1.00 67.20  ? 808 PRO A N   1 
ATOM 5007 C CA  . PRO A 1 638 ? 158.039 165.102 156.662 1.00 66.43  ? 808 PRO A CA  1 
ATOM 5008 C C   . PRO A 1 638 ? 159.451 165.276 157.191 1.00 66.61  ? 808 PRO A C   1 
ATOM 5009 O O   . PRO A 1 638 ? 159.934 164.443 157.976 1.00 65.47  ? 808 PRO A O   1 
ATOM 5010 C CB  . PRO A 1 638 ? 157.100 165.918 157.563 1.00 66.02  ? 808 PRO A CB  1 
ATOM 5011 C CG  . PRO A 1 638 ? 156.731 164.981 158.641 1.00 65.55  ? 808 PRO A CG  1 
ATOM 5012 C CD  . PRO A 1 638 ? 156.602 163.637 157.977 1.00 66.38  ? 808 PRO A CD  1 
ATOM 5013 N N   . ALA A 1 639 ? 160.078 166.386 156.805 1.00 67.05  ? 809 ALA A N   1 
ATOM 5014 C CA  . ALA A 1 639 ? 161.410 166.755 157.295 1.00 67.35  ? 809 ALA A CA  1 
ATOM 5015 C C   . ALA A 1 639 ? 162.507 165.742 157.045 1.00 68.01  ? 809 ALA A C   1 
ATOM 5016 O O   . ALA A 1 639 ? 163.397 165.589 157.887 1.00 69.13  ? 809 ALA A O   1 
ATOM 5017 C CB  . ALA A 1 639 ? 161.328 167.057 158.806 1.00 66.57  ? 809 ALA A CB  1 
ATOM 5018 N N   . THR A 1 640 ? 162.461 165.031 155.928 1.00 68.06  ? 810 THR A N   1 
ATOM 5019 C CA  . THR A 1 640 ? 163.503 164.042 155.652 1.00 68.30  ? 810 THR A CA  1 
ATOM 5020 C C   . THR A 1 640 ? 163.830 163.992 154.171 1.00 68.43  ? 810 THR A C   1 
ATOM 5021 O O   . THR A 1 640 ? 163.134 164.590 153.356 1.00 68.51  ? 810 THR A O   1 
ATOM 5022 C CB  . THR A 1 640 ? 163.043 162.626 156.021 1.00 68.79  ? 810 THR A CB  1 
ATOM 5023 O OG1 . THR A 1 640 ? 161.930 162.252 155.183 1.00 68.41  ? 810 THR A OG1 1 
ATOM 5024 C CG2 . THR A 1 640 ? 162.668 162.522 157.505 1.00 67.79  ? 810 THR A CG2 1 
ATOM 5025 N N   . VAL A 1 641 ? 164.865 163.244 153.816 1.00 68.34  ? 811 VAL A N   1 
ATOM 5026 C CA  . VAL A 1 641 ? 165.221 163.108 152.418 1.00 68.47  ? 811 VAL A CA  1 
ATOM 5027 C C   . VAL A 1 641 ? 164.247 162.178 151.735 1.00 68.69  ? 811 VAL A C   1 
ATOM 5028 O O   . VAL A 1 641 ? 163.743 162.510 150.666 1.00 69.23  ? 811 VAL A O   1 
ATOM 5029 C CB  . VAL A 1 641 ? 166.640 162.606 152.223 1.00 68.39  ? 811 VAL A CB  1 
ATOM 5030 C CG1 . VAL A 1 641 ? 166.911 162.387 150.731 1.00 68.70  ? 811 VAL A CG1 1 
ATOM 5031 C CG2 . VAL A 1 641 ? 167.615 163.624 152.799 1.00 67.84  ? 811 VAL A CG2 1 
ATOM 5032 N N   . HIS A 1 642 ? 163.953 161.028 152.350 1.00 68.76  ? 812 HIS A N   1 
ATOM 5033 C CA  . HIS A 1 642 ? 163.006 160.088 151.737 1.00 68.60  ? 812 HIS A CA  1 
ATOM 5034 C C   . HIS A 1 642 ? 161.633 160.731 151.545 1.00 68.54  ? 812 HIS A C   1 
ATOM 5035 O O   . HIS A 1 642 ? 160.957 160.471 150.552 1.00 69.27  ? 812 HIS A O   1 
ATOM 5036 C CB  . HIS A 1 642 ? 162.926 158.774 152.501 1.00 68.49  ? 812 HIS A CB  1 
ATOM 5037 C CG  . HIS A 1 642 ? 162.594 158.928 153.947 1.00 70.51  ? 812 HIS A CG  1 
ATOM 5038 N ND1 . HIS A 1 642 ? 163.557 159.124 154.914 1.00 70.87  ? 812 HIS A ND1 1 
ATOM 5039 C CD2 . HIS A 1 642 ? 161.403 158.894 154.598 1.00 71.11  ? 812 HIS A CD2 1 
ATOM 5040 C CE1 . HIS A 1 642 ? 162.973 159.219 156.096 1.00 71.82  ? 812 HIS A CE1 1 
ATOM 5041 N NE2 . HIS A 1 642 ? 161.668 159.084 155.932 1.00 72.32  ? 812 HIS A NE2 1 
ATOM 5042 N N   . GLY A 1 643 ? 161.244 161.598 152.475 1.00 68.35  ? 813 GLY A N   1 
ATOM 5043 C CA  . GLY A 1 643 ? 159.975 162.307 152.395 1.00 67.95  ? 813 GLY A CA  1 
ATOM 5044 C C   . GLY A 1 643 ? 159.971 163.201 151.173 1.00 68.69  ? 813 GLY A C   1 
ATOM 5045 O O   . GLY A 1 643 ? 159.005 163.215 150.403 1.00 69.75  ? 813 GLY A O   1 
ATOM 5046 N N   . ALA A 1 644 ? 161.056 163.959 150.987 1.00 67.96  ? 814 ALA A N   1 
ATOM 5047 C CA  . ALA A 1 644 ? 161.171 164.809 149.780 1.00 67.84  ? 814 ALA A CA  1 
ATOM 5048 C C   . ALA A 1 644 ? 161.209 163.903 148.547 1.00 68.50  ? 814 ALA A C   1 
ATOM 5049 O O   . ALA A 1 644 ? 160.523 164.221 147.556 1.00 68.55  ? 814 ALA A O   1 
ATOM 5050 C CB  . ALA A 1 644 ? 162.404 165.672 149.872 1.00 67.98  ? 814 ALA A CB  1 
ATOM 5051 N N   . LEU A 1 645 ? 161.968 162.806 148.624 1.00 68.78  ? 815 LEU A N   1 
ATOM 5052 C CA  . LEU A 1 645 ? 162.069 161.851 147.488 1.00 68.96  ? 815 LEU A CA  1 
ATOM 5053 C C   . LEU A 1 645 ? 160.664 161.366 147.121 1.00 69.22  ? 815 LEU A C   1 
ATOM 5054 O O   . LEU A 1 645 ? 160.346 161.339 145.916 1.00 69.55  ? 815 LEU A O   1 
ATOM 5055 C CB  . LEU A 1 645 ? 162.964 160.685 147.923 1.00 69.52  ? 815 LEU A CB  1 
ATOM 5056 C CG  . LEU A 1 645 ? 163.122 159.539 146.923 1.00 69.53  ? 815 LEU A CG  1 
ATOM 5057 C CD1 . LEU A 1 645 ? 161.963 158.557 147.012 1.00 71.14  ? 815 LEU A CD1 1 
ATOM 5058 C CD2 . LEU A 1 645 ? 163.287 160.061 145.505 1.00 73.15  ? 815 LEU A CD2 1 
ATOM 5059 N N   . LEU A 1 646 ? 159.856 161.011 148.124 1.00 68.89  ? 816 LEU A N   1 
ATOM 5060 C CA  . LEU A 1 646 ? 158.495 160.473 147.859 1.00 68.20  ? 816 LEU A CA  1 
ATOM 5061 C C   . LEU A 1 646 ? 157.597 161.583 147.304 1.00 68.13  ? 816 LEU A C   1 
ATOM 5062 O O   . LEU A 1 646 ? 156.890 161.321 146.311 1.00 68.14  ? 816 LEU A O   1 
ATOM 5063 C CB  . LEU A 1 646 ? 157.928 159.900 149.162 1.00 67.57  ? 816 LEU A CB  1 
ATOM 5064 C CG  . LEU A 1 646 ? 158.686 158.702 149.732 1.00 68.17  ? 816 LEU A CG  1 
ATOM 5065 C CD1 . LEU A 1 646 ? 158.169 158.338 151.116 1.00 67.41  ? 816 LEU A CD1 1 
ATOM 5066 C CD2 . LEU A 1 646 ? 158.599 157.508 148.795 1.00 64.92  ? 816 LEU A CD2 1 
ATOM 5067 N N   . SER A 1 647 ? 157.622 162.772 147.916 1.00 68.09  ? 817 SER A N   1 
ATOM 5068 C CA  . SER A 1 647 ? 156.724 163.844 147.478 1.00 68.33  ? 817 SER A CA  1 
ATOM 5069 C C   . SER A 1 647 ? 156.890 164.119 145.992 1.00 68.25  ? 817 SER A C   1 
ATOM 5070 O O   . SER A 1 647 ? 155.905 164.342 145.307 1.00 68.57  ? 817 SER A O   1 
ATOM 5071 C CB  . SER A 1 647 ? 156.872 165.123 148.300 1.00 68.60  ? 817 SER A CB  1 
ATOM 5072 O OG  . SER A 1 647 ? 158.070 165.812 148.013 1.00 69.22  ? 817 SER A OG  1 
ATOM 5073 N N   . GLY A 1 648 ? 158.120 164.056 145.483 1.00 67.88  ? 818 GLY A N   1 
ATOM 5074 C CA  . GLY A 1 648 ? 158.360 164.292 144.060 1.00 67.73  ? 818 GLY A CA  1 
ATOM 5075 C C   . GLY A 1 648 ? 157.726 163.182 143.222 1.00 68.13  ? 818 GLY A C   1 
ATOM 5076 O O   . GLY A 1 648 ? 157.099 163.436 142.185 1.00 67.65  ? 818 GLY A O   1 
ATOM 5077 N N   . LEU A 1 649 ? 157.886 161.939 143.676 1.00 67.87  ? 819 LEU A N   1 
ATOM 5078 C CA  . LEU A 1 649 ? 157.325 160.803 142.965 1.00 67.44  ? 819 LEU A CA  1 
ATOM 5079 C C   . LEU A 1 649 ? 155.810 160.955 142.890 1.00 67.31  ? 819 LEU A C   1 
ATOM 5080 O O   . LEU A 1 649 ? 155.213 160.696 141.838 1.00 68.03  ? 819 LEU A O   1 
ATOM 5081 C CB  . LEU A 1 649 ? 157.714 159.485 143.632 1.00 67.29  ? 819 LEU A CB  1 
ATOM 5082 C CG  . LEU A 1 649 ? 159.209 159.150 143.743 1.00 67.72  ? 819 LEU A CG  1 
ATOM 5083 C CD1 . LEU A 1 649 ? 159.414 157.758 144.334 1.00 66.71  ? 819 LEU A CD1 1 
ATOM 5084 C CD2 . LEU A 1 649 ? 159.918 159.273 142.400 1.00 66.24  ? 819 LEU A CD2 1 
ATOM 5085 N N   . ARG A 1 650 ? 155.206 161.424 143.978 1.00 66.39  ? 820 ARG A N   1 
ATOM 5086 C CA  . ARG A 1 650 ? 153.768 161.622 144.041 1.00 65.98  ? 820 ARG A CA  1 
ATOM 5087 C C   . ARG A 1 650 ? 153.316 162.671 143.035 1.00 67.06  ? 820 ARG A C   1 
ATOM 5088 O O   . ARG A 1 650 ? 152.465 162.383 142.190 1.00 68.56  ? 820 ARG A O   1 
ATOM 5089 C CB  . ARG A 1 650 ? 153.351 162.001 145.460 1.00 65.63  ? 820 ARG A CB  1 
ATOM 5090 C CG  . ARG A 1 650 ? 151.907 162.401 145.612 1.00 64.43  ? 820 ARG A CG  1 
ATOM 5091 C CD  . ARG A 1 650 ? 151.706 163.154 146.913 1.00 63.97  ? 820 ARG A CD  1 
ATOM 5092 N NE  . ARG A 1 650 ? 152.211 164.529 146.814 1.00 65.30  ? 820 ARG A NE  1 
ATOM 5093 C CZ  . ARG A 1 650 ? 152.824 165.190 147.799 1.00 66.86  ? 820 ARG A CZ  1 
ATOM 5094 N NH1 . ARG A 1 650 ? 153.049 164.604 148.988 1.00 65.92  ? 820 ARG A NH1 1 
ATOM 5095 N NH2 . ARG A 1 650 ? 153.230 166.434 147.595 1.00 65.56  ? 820 ARG A NH2 1 
ATOM 5096 N N   . GLU A 1 651 ? 153.889 163.872 143.078 1.00 67.06  ? 821 GLU A N   1 
ATOM 5097 C CA  . GLU A 1 651 ? 153.475 164.892 142.141 1.00 67.41  ? 821 GLU A CA  1 
ATOM 5098 C C   . GLU A 1 651 ? 153.737 164.513 140.686 1.00 67.70  ? 821 GLU A C   1 
ATOM 5099 O O   . GLU A 1 651 ? 152.939 164.856 139.806 1.00 68.98  ? 821 GLU A O   1 
ATOM 5100 C CB  . GLU A 1 651 ? 154.059 166.256 142.478 1.00 67.26  ? 821 GLU A CB  1 
ATOM 5101 C CG  . GLU A 1 651 ? 153.571 166.829 143.805 1.00 69.35  ? 821 GLU A CG  1 
ATOM 5102 C CD  . GLU A 1 651 ? 152.033 166.871 143.975 1.00 71.74  ? 821 GLU A CD  1 
ATOM 5103 O OE1 . GLU A 1 651 ? 151.327 167.433 143.113 1.00 72.64  ? 821 GLU A OE1 1 
ATOM 5104 O OE2 . GLU A 1 651 ? 151.531 166.372 145.004 1.00 71.37  ? 821 GLU A OE2 1 
ATOM 5105 N N   . ALA A 1 652 ? 154.823 163.803 140.408 1.00 67.29  ? 822 ALA A N   1 
ATOM 5106 C CA  . ALA A 1 652 ? 155.091 163.416 139.026 1.00 66.66  ? 822 ALA A CA  1 
ATOM 5107 C C   . ALA A 1 652 ? 153.928 162.552 138.541 1.00 66.68  ? 822 ALA A C   1 
ATOM 5108 O O   . ALA A 1 652 ? 153.423 162.752 137.446 1.00 66.94  ? 822 ALA A O   1 
ATOM 5109 C CB  . ALA A 1 652 ? 156.394 162.687 138.902 1.00 66.40  ? 822 ALA A CB  1 
ATOM 5110 N N   . GLY A 1 653 ? 153.471 161.627 139.379 1.00 66.58  ? 823 GLY A N   1 
ATOM 5111 C CA  . GLY A 1 653 ? 152.351 160.772 139.011 1.00 66.53  ? 823 GLY A CA  1 
ATOM 5112 C C   . GLY A 1 653 ? 151.057 161.554 138.822 1.00 66.66  ? 823 GLY A C   1 
ATOM 5113 O O   . GLY A 1 653 ? 150.272 161.281 137.905 1.00 66.49  ? 823 GLY A O   1 
ATOM 5114 N N   . ARG A 1 654 ? 150.828 162.547 139.672 1.00 66.77  ? 824 ARG A N   1 
ATOM 5115 C CA  . ARG A 1 654 ? 149.597 163.315 139.557 1.00 67.11  ? 824 ARG A CA  1 
ATOM 5116 C C   . ARG A 1 654 ? 149.602 164.199 138.309 1.00 67.13  ? 824 ARG A C   1 
ATOM 5117 O O   . ARG A 1 654 ? 148.579 164.292 137.596 1.00 67.50  ? 824 ARG A O   1 
ATOM 5118 C CB  . ARG A 1 654 ? 149.292 164.065 140.851 1.00 67.28  ? 824 ARG A CB  1 
ATOM 5119 C CG  . ARG A 1 654 ? 148.546 165.339 140.636 1.00 70.63  ? 824 ARG A CG  1 
ATOM 5120 C CD  . ARG A 1 654 ? 147.893 165.864 141.883 1.00 75.46  ? 824 ARG A CD  1 
ATOM 5121 N NE  . ARG A 1 654 ? 148.775 165.965 143.042 1.00 75.36  ? 824 ARG A NE  1 
ATOM 5122 C CZ  . ARG A 1 654 ? 148.344 165.760 144.283 1.00 76.80  ? 824 ARG A CZ  1 
ATOM 5123 N NH1 . ARG A 1 654 ? 147.067 165.455 144.489 1.00 76.32  ? 824 ARG A NH1 1 
ATOM 5124 N NH2 . ARG A 1 654 ? 149.174 165.852 145.312 1.00 76.73  ? 824 ARG A NH2 1 
ATOM 5125 N N   . ILE A 1 655 ? 150.758 164.805 138.021 1.00 66.53  ? 825 ILE A N   1 
ATOM 5126 C CA  . ILE A 1 655 ? 150.897 165.647 136.839 1.00 65.98  ? 825 ILE A CA  1 
ATOM 5127 C C   . ILE A 1 655 ? 150.721 164.801 135.581 1.00 66.49  ? 825 ILE A C   1 
ATOM 5128 O O   . ILE A 1 655 ? 149.931 165.138 134.705 1.00 66.32  ? 825 ILE A O   1 
ATOM 5129 C CB  . ILE A 1 655 ? 152.226 166.448 136.827 1.00 65.57  ? 825 ILE A CB  1 
ATOM 5130 C CG1 . ILE A 1 655 ? 152.205 167.507 137.934 1.00 64.12  ? 825 ILE A CG1 1 
ATOM 5131 C CG2 . ILE A 1 655 ? 152.436 167.119 135.481 1.00 63.08  ? 825 ILE A CG2 1 
ATOM 5132 C CD1 . ILE A 1 655 ? 153.552 168.066 138.291 1.00 62.83  ? 825 ILE A CD1 1 
ATOM 5133 N N   . ALA A 1 656 ? 151.431 163.689 135.507 1.00 67.53  ? 826 ALA A N   1 
ATOM 5134 C CA  . ALA A 1 656 ? 151.315 162.818 134.352 1.00 69.27  ? 826 ALA A CA  1 
ATOM 5135 C C   . ALA A 1 656 ? 149.876 162.335 134.155 1.00 70.45  ? 826 ALA A C   1 
ATOM 5136 O O   . ALA A 1 656 ? 149.408 162.220 133.022 1.00 70.44  ? 826 ALA A O   1 
ATOM 5137 C CB  . ALA A 1 656 ? 152.256 161.644 134.477 1.00 69.25  ? 826 ALA A CB  1 
ATOM 5138 N N   . ASP A 1 657 ? 149.173 162.056 135.253 1.00 71.93  ? 827 ASP A N   1 
ATOM 5139 C CA  . ASP A 1 657 ? 147.779 161.589 135.169 1.00 73.47  ? 827 ASP A CA  1 
ATOM 5140 C C   . ASP A 1 657 ? 146.901 162.683 134.593 1.00 74.10  ? 827 ASP A C   1 
ATOM 5141 O O   . ASP A 1 657 ? 146.019 162.425 133.784 1.00 74.39  ? 827 ASP A O   1 
ATOM 5142 C CB  . ASP A 1 657 ? 147.239 161.193 136.550 1.00 73.69  ? 827 ASP A CB  1 
ATOM 5143 C CG  . ASP A 1 657 ? 147.649 159.792 136.967 1.00 75.08  ? 827 ASP A CG  1 
ATOM 5144 O OD1 . ASP A 1 657 ? 148.180 159.025 136.119 1.00 77.61  ? 827 ASP A OD1 1 
ATOM 5145 O OD2 . ASP A 1 657 ? 147.425 159.452 138.145 1.00 74.93  ? 827 ASP A OD2 1 
ATOM 5146 N N   . GLN A 1 658 ? 147.166 163.910 135.021 1.00 74.77  ? 828 GLN A N   1 
ATOM 5147 C CA  . GLN A 1 658 ? 146.417 165.059 134.582 1.00 75.50  ? 828 GLN A CA  1 
ATOM 5148 C C   . GLN A 1 658 ? 146.636 165.394 133.117 1.00 75.18  ? 828 GLN A C   1 
ATOM 5149 O O   . GLN A 1 658 ? 145.684 165.606 132.394 1.00 75.17  ? 828 GLN A O   1 
ATOM 5150 C CB  . GLN A 1 658 ? 146.788 166.268 135.447 1.00 76.33  ? 828 GLN A CB  1 
ATOM 5151 C CG  . GLN A 1 658 ? 145.961 167.521 135.187 1.00 80.24  ? 828 GLN A CG  1 
ATOM 5152 C CD  . GLN A 1 658 ? 144.477 167.225 135.303 1.00 86.52  ? 828 GLN A CD  1 
ATOM 5153 O OE1 . GLN A 1 658 ? 143.714 167.461 134.364 1.00 89.11  ? 828 GLN A OE1 1 
ATOM 5154 N NE2 . GLN A 1 658 ? 144.063 166.664 136.448 1.00 88.26  ? 828 GLN A NE2 1 
ATOM 5155 N N   . PHE A 1 659 ? 147.893 165.448 132.692 1.00 75.10  ? 829 PHE A N   1 
ATOM 5156 C CA  . PHE A 1 659 ? 148.245 165.832 131.325 1.00 74.50  ? 829 PHE A CA  1 
ATOM 5157 C C   . PHE A 1 659 ? 148.507 164.749 130.288 1.00 75.35  ? 829 PHE A C   1 
ATOM 5158 O O   . PHE A 1 659 ? 148.475 165.039 129.103 1.00 75.51  ? 829 PHE A O   1 
ATOM 5159 C CB  . PHE A 1 659 ? 149.410 166.817 131.371 1.00 73.36  ? 829 PHE A CB  1 
ATOM 5160 C CG  . PHE A 1 659 ? 149.087 168.086 132.096 1.00 71.96  ? 829 PHE A CG  1 
ATOM 5161 C CD1 . PHE A 1 659 ? 148.540 169.169 131.418 1.00 70.02  ? 829 PHE A CD1 1 
ATOM 5162 C CD2 . PHE A 1 659 ? 149.311 168.199 133.464 1.00 70.94  ? 829 PHE A CD2 1 
ATOM 5163 C CE1 . PHE A 1 659 ? 148.226 170.340 132.085 1.00 68.96  ? 829 PHE A CE1 1 
ATOM 5164 C CE2 . PHE A 1 659 ? 148.999 169.372 134.135 1.00 69.41  ? 829 PHE A CE2 1 
ATOM 5165 C CZ  . PHE A 1 659 ? 148.457 170.440 133.448 1.00 69.44  ? 829 PHE A CZ  1 
ATOM 5166 N N   . LEU A 1 660 ? 148.767 163.518 130.706 1.00 76.39  ? 830 LEU A N   1 
ATOM 5167 C CA  . LEU A 1 660 ? 149.007 162.445 129.741 1.00 77.48  ? 830 LEU A CA  1 
ATOM 5168 C C   . LEU A 1 660 ? 147.851 161.457 129.738 1.00 78.78  ? 830 LEU A C   1 
ATOM 5169 O O   . LEU A 1 660 ? 147.703 160.660 128.815 1.00 78.43  ? 830 LEU A O   1 
ATOM 5170 C CB  . LEU A 1 660 ? 150.320 161.712 130.026 1.00 76.99  ? 830 LEU A CB  1 
ATOM 5171 C CG  . LEU A 1 660 ? 151.607 162.532 130.125 1.00 77.08  ? 830 LEU A CG  1 
ATOM 5172 C CD1 . LEU A 1 660 ? 152.769 161.656 130.564 1.00 76.43  ? 830 LEU A CD1 1 
ATOM 5173 C CD2 . LEU A 1 660 ? 151.924 163.209 128.807 1.00 76.86  ? 830 LEU A CD2 1 
ATOM 5174 N N   . GLY A 1 661 ? 147.038 161.520 130.784 1.00 80.97  ? 831 GLY A N   1 
ATOM 5175 C CA  . GLY A 1 661 ? 145.905 160.634 130.946 1.00 83.71  ? 831 GLY A CA  1 
ATOM 5176 C C   . GLY A 1 661 ? 146.367 159.336 131.571 1.00 86.11  ? 831 GLY A C   1 
ATOM 5177 O O   . GLY A 1 661 ? 147.555 159.009 131.551 1.00 85.72  ? 831 GLY A O   1 
ATOM 5178 N N   . ALA A 1 662 ? 145.416 158.598 132.128 1.00 89.12  ? 832 ALA A N   1 
ATOM 5179 C CA  . ALA A 1 662 ? 145.688 157.318 132.771 1.00 92.22  ? 832 ALA A CA  1 
ATOM 5180 C C   . ALA A 1 662 ? 144.972 156.213 132.009 1.00 94.45  ? 832 ALA A C   1 
ATOM 5181 O O   . ALA A 1 662 ? 143.767 156.298 131.780 1.00 95.24  ? 832 ALA A O   1 
ATOM 5182 C CB  . ALA A 1 662 ? 145.216 157.358 134.222 1.00 92.11  ? 832 ALA A CB  1 
ATOM 5183 N N   . MET A 1 663 ? 145.698 155.179 131.601 1.00 97.11  ? 833 MET A N   1 
ATOM 5184 C CA  . MET A 1 663 ? 145.054 154.086 130.864 1.00 99.43  ? 833 MET A CA  1 
ATOM 5185 C C   . MET A 1 663 ? 144.805 152.860 131.754 1.00 100.23 ? 833 MET A C   1 
ATOM 5186 O O   . MET A 1 663 ? 144.094 151.926 131.360 1.00 100.41 ? 833 MET A O   1 
ATOM 5187 C CB  . MET A 1 663 ? 145.847 153.744 129.597 1.00 100.24 ? 833 MET A CB  1 
ATOM 5188 C CG  . MET A 1 663 ? 146.193 154.980 128.743 1.00 102.30 ? 833 MET A CG  1 
ATOM 5189 S SD  . MET A 1 663 ? 144.802 155.713 127.825 1.00 107.59 ? 833 MET A SD  1 
ATOM 5190 C CE  . MET A 1 663 ? 145.490 157.313 127.326 1.00 103.80 ? 833 MET A CE  1 
ATOM 5191 N N   . TYR A 1 664 ? 145.374 152.906 132.964 1.00 101.24 ? 834 TYR A N   1 
ATOM 5192 C CA  . TYR A 1 664 ? 145.267 151.839 133.984 1.00 102.22 ? 834 TYR A CA  1 
ATOM 5193 C C   . TYR A 1 664 ? 144.044 151.953 134.921 1.00 102.79 ? 834 TYR A C   1 
ATOM 5194 O O   . TYR A 1 664 ? 143.695 150.988 135.626 1.00 102.59 ? 834 TYR A O   1 
ATOM 5195 C CB  . TYR A 1 664 ? 146.550 151.795 134.828 1.00 102.03 ? 834 TYR A CB  1 
ATOM 5196 C CG  . TYR A 1 664 ? 146.828 153.085 135.573 1.00 102.55 ? 834 TYR A CG  1 
ATOM 5197 C CD1 . TYR A 1 664 ? 147.472 154.160 134.944 1.00 102.37 ? 834 TYR A CD1 1 
ATOM 5198 C CD2 . TYR A 1 664 ? 146.442 153.238 136.907 1.00 102.54 ? 834 TYR A CD2 1 
ATOM 5199 C CE1 . TYR A 1 664 ? 147.723 155.345 135.630 1.00 101.95 ? 834 TYR A CE1 1 
ATOM 5200 C CE2 . TYR A 1 664 ? 146.690 154.420 137.596 1.00 101.88 ? 834 TYR A CE2 1 
ATOM 5201 C CZ  . TYR A 1 664 ? 147.327 155.463 136.957 1.00 101.87 ? 834 TYR A CZ  1 
ATOM 5202 O OH  . TYR A 1 664 ? 147.564 156.627 137.650 1.00 102.25 ? 834 TYR A OH  1 
ATOM 5203 N N   . THR A 1 665 ? 143.418 153.137 134.926 1.00 103.60 ? 835 THR A N   1 
ATOM 5204 C CA  . THR A 1 665 ? 142.241 153.427 135.761 1.00 104.12 ? 835 THR A CA  1 
ATOM 5205 C C   . THR A 1 665 ? 140.929 152.884 135.176 1.00 104.51 ? 835 THR A C   1 
ATOM 5206 O O   . THR A 1 665 ? 139.989 152.626 135.927 1.00 104.72 ? 835 THR A O   1 
ATOM 5207 C CB  . THR A 1 665 ? 142.076 154.950 136.054 1.00 104.20 ? 835 THR A CB  1 
ATOM 5208 O OG1 . THR A 1 665 ? 142.021 155.683 134.819 1.00 103.99 ? 835 THR A OG1 1 
ATOM 5209 C CG2 . THR A 1 665 ? 143.219 155.485 136.936 1.00 103.87 ? 835 THR A CG2 1 
ATOM 5210 N N   . LEU A 1 666 ? 140.871 152.721 133.849 1.00 104.85 ? 836 LEU A N   1 
ATOM 5211 C CA  . LEU A 1 666 ? 139.675 152.202 133.163 1.00 105.12 ? 836 LEU A CA  1 
ATOM 5212 C C   . LEU A 1 666 ? 139.414 150.722 133.462 1.00 105.10 ? 836 LEU A C   1 
ATOM 5213 O O   . LEU A 1 666 ? 138.604 150.381 134.330 1.00 105.06 ? 836 LEU A O   1 
ATOM 5214 C CB  . LEU A 1 666 ? 139.784 152.411 131.648 1.00 105.11 ? 836 LEU A CB  1 
ATOM 5215 C CG  . LEU A 1 666 ? 139.107 153.637 131.022 1.00 105.61 ? 836 LEU A CG  1 
ATOM 5216 C CD1 . LEU A 1 666 ? 139.837 154.951 131.347 1.00 105.58 ? 836 LEU A CD1 1 
ATOM 5217 C CD2 . LEU A 1 666 ? 138.969 153.443 129.507 1.00 105.30 ? 836 LEU A CD2 1 
ATOM 5218 N N   . ARG B 2 1   ? 145.945 154.585 179.948 1.00 75.91  ? 308 ARG B N   1 
ATOM 5219 C CA  . ARG B 2 1   ? 145.026 154.641 181.130 1.00 75.91  ? 308 ARG B CA  1 
ATOM 5220 C C   . ARG B 2 1   ? 145.701 155.197 182.382 1.00 75.66  ? 308 ARG B C   1 
ATOM 5221 O O   . ARG B 2 1   ? 145.040 155.825 183.212 1.00 75.89  ? 308 ARG B O   1 
ATOM 5222 C CB  . ARG B 2 1   ? 144.424 153.257 181.456 1.00 76.05  ? 308 ARG B CB  1 
ATOM 5223 C CG  . ARG B 2 1   ? 143.635 152.579 180.332 1.00 76.71  ? 308 ARG B CG  1 
ATOM 5224 C CD  . ARG B 2 1   ? 142.515 153.464 179.797 1.00 77.59  ? 308 ARG B CD  1 
ATOM 5225 N NE  . ARG B 2 1   ? 142.081 153.040 178.468 1.00 78.18  ? 308 ARG B NE  1 
ATOM 5226 C CZ  . ARG B 2 1   ? 141.588 153.857 177.537 1.00 78.38  ? 308 ARG B CZ  1 
ATOM 5227 N NH1 . ARG B 2 1   ? 141.465 155.157 177.781 1.00 78.18  ? 308 ARG B NH1 1 
ATOM 5228 N NH2 . ARG B 2 1   ? 141.224 153.376 176.353 1.00 77.46  ? 308 ARG B NH2 1 
ATOM 5229 N N   . LYS B 2 2   ? 147.000 154.946 182.540 1.00 75.24  ? 309 LYS B N   1 
ATOM 5230 C CA  . LYS B 2 2   ? 147.729 155.418 183.727 1.00 74.66  ? 309 LYS B CA  1 
ATOM 5231 C C   . LYS B 2 2   ? 149.058 156.140 183.442 1.00 73.90  ? 309 LYS B C   1 
ATOM 5232 O O   . LYS B 2 2   ? 149.713 155.875 182.426 1.00 73.79  ? 309 LYS B O   1 
ATOM 5233 C CB  . LYS B 2 2   ? 147.971 154.256 184.705 1.00 74.95  ? 309 LYS B CB  1 
ATOM 5234 C CG  . LYS B 2 2   ? 146.715 153.713 185.392 1.00 75.86  ? 309 LYS B CG  1 
ATOM 5235 C CD  . LYS B 2 2   ? 147.036 153.107 186.760 1.00 76.96  ? 309 LYS B CD  1 
ATOM 5236 C CE  . LYS B 2 2   ? 145.839 152.347 187.335 1.00 77.57  ? 309 LYS B CE  1 
ATOM 5237 N NZ  . LYS B 2 2   ? 145.970 152.112 188.806 1.00 77.52  ? 309 LYS B NZ  1 
ATOM 5238 N N   . PRO B 2 3   ? 149.458 157.059 184.345 1.00 73.18  ? 310 PRO B N   1 
ATOM 5239 C CA  . PRO B 2 3   ? 150.785 157.658 184.289 1.00 72.82  ? 310 PRO B CA  1 
ATOM 5240 C C   . PRO B 2 3   ? 151.835 156.573 184.472 1.00 72.61  ? 310 PRO B C   1 
ATOM 5241 O O   . PRO B 2 3   ? 151.510 155.500 184.969 1.00 72.79  ? 310 PRO B O   1 
ATOM 5242 C CB  . PRO B 2 3   ? 150.810 158.571 185.519 1.00 72.68  ? 310 PRO B CB  1 
ATOM 5243 C CG  . PRO B 2 3   ? 149.405 158.808 185.866 1.00 72.70  ? 310 PRO B CG  1 
ATOM 5244 C CD  . PRO B 2 3   ? 148.676 157.574 185.482 1.00 73.18  ? 310 PRO B CD  1 
ATOM 5245 N N   . PRO B 2 4   ? 153.087 156.832 184.068 1.00 72.40  ? 311 PRO B N   1 
ATOM 5246 C CA  . PRO B 2 4   ? 154.146 155.887 184.427 1.00 72.20  ? 311 PRO B CA  1 
ATOM 5247 C C   . PRO B 2 4   ? 154.212 155.684 185.940 1.00 72.00  ? 311 PRO B C   1 
ATOM 5248 O O   . PRO B 2 4   ? 153.858 156.589 186.691 1.00 71.99  ? 311 PRO B O   1 
ATOM 5249 C CB  . PRO B 2 4   ? 155.411 156.577 183.922 1.00 72.28  ? 311 PRO B CB  1 
ATOM 5250 C CG  . PRO B 2 4   ? 154.935 157.457 182.812 1.00 72.26  ? 311 PRO B CG  1 
ATOM 5251 C CD  . PRO B 2 4   ? 153.595 157.950 183.254 1.00 72.28  ? 311 PRO B CD  1 
ATOM 5252 N N   . LYS B 2 5   ? 154.631 154.498 186.373 1.00 71.93  ? 312 LYS B N   1 
ATOM 5253 C CA  . LYS B 2 5   ? 154.724 154.173 187.797 1.00 71.99  ? 312 LYS B CA  1 
ATOM 5254 C C   . LYS B 2 5   ? 155.639 155.145 188.529 1.00 71.64  ? 312 LYS B C   1 
ATOM 5255 O O   . LYS B 2 5   ? 156.773 155.370 188.117 1.00 71.64  ? 312 LYS B O   1 
ATOM 5256 C CB  . LYS B 2 5   ? 155.195 152.724 187.996 1.00 72.22  ? 312 LYS B CB  1 
ATOM 5257 C CG  . LYS B 2 5   ? 154.057 151.704 188.010 1.00 73.32  ? 312 LYS B CG  1 
ATOM 5258 C CD  . LYS B 2 5   ? 154.358 150.498 187.111 1.00 75.18  ? 312 LYS B CD  1 
ATOM 5259 C CE  . LYS B 2 5   ? 153.172 149.533 187.038 1.00 75.47  ? 312 LYS B CE  1 
ATOM 5260 N NZ  . LYS B 2 5   ? 153.311 148.538 185.938 1.00 75.56  ? 312 LYS B NZ  1 
ATOM 5261 N N   . GLY B 2 6   ? 155.132 155.743 189.598 1.00 71.19  ? 313 GLY B N   1 
ATOM 5262 C CA  . GLY B 2 6   ? 155.926 156.693 190.358 1.00 71.01  ? 313 GLY B CA  1 
ATOM 5263 C C   . GLY B 2 6   ? 155.714 158.140 189.956 1.00 70.83  ? 313 GLY B C   1 
ATOM 5264 O O   . GLY B 2 6   ? 156.092 159.050 190.701 1.00 71.15  ? 313 GLY B O   1 
ATOM 5265 N N   . MET B 2 7   ? 155.122 158.355 188.781 1.00 70.23  ? 314 MET B N   1 
ATOM 5266 C CA  . MET B 2 7   ? 154.829 159.691 188.271 1.00 69.68  ? 314 MET B CA  1 
ATOM 5267 C C   . MET B 2 7   ? 153.439 160.078 188.779 1.00 69.33  ? 314 MET B C   1 
ATOM 5268 O O   . MET B 2 7   ? 152.520 159.267 188.748 1.00 69.55  ? 314 MET B O   1 
ATOM 5269 C CB  . MET B 2 7   ? 154.842 159.669 186.747 1.00 69.83  ? 314 MET B CB  1 
ATOM 5270 C CG  . MET B 2 7   ? 155.116 161.002 186.078 1.00 69.99  ? 314 MET B CG  1 
ATOM 5271 S SD  . MET B 2 7   ? 156.851 161.228 185.630 1.00 69.97  ? 314 MET B SD  1 
ATOM 5272 C CE  . MET B 2 7   ? 157.155 159.723 184.745 1.00 70.58  ? 314 MET B CE  1 
ATOM 5273 N N   . PHE B 2 8   ? 153.282 161.303 189.259 1.00 68.88  ? 315 PHE B N   1 
ATOM 5274 C CA  . PHE B 2 8   ? 151.997 161.745 189.793 1.00 68.72  ? 315 PHE B CA  1 
ATOM 5275 C C   . PHE B 2 8   ? 151.421 162.909 189.011 1.00 68.09  ? 315 PHE B C   1 
ATOM 5276 O O   . PHE B 2 8   ? 152.075 163.941 188.858 1.00 67.71  ? 315 PHE B O   1 
ATOM 5277 C CB  . PHE B 2 8   ? 152.132 162.068 191.294 1.00 69.31  ? 315 PHE B CB  1 
ATOM 5278 C CG  . PHE B 2 8   ? 152.420 160.860 192.133 1.00 70.42  ? 315 PHE B CG  1 
ATOM 5279 C CD1 . PHE B 2 8   ? 153.716 160.333 192.201 1.00 71.02  ? 315 PHE B CD1 1 
ATOM 5280 C CD2 . PHE B 2 8   ? 151.390 160.214 192.817 1.00 71.85  ? 315 PHE B CD2 1 
ATOM 5281 C CE1 . PHE B 2 8   ? 153.985 159.180 192.946 1.00 71.25  ? 315 PHE B CE1 1 
ATOM 5282 C CE2 . PHE B 2 8   ? 151.646 159.062 193.572 1.00 71.84  ? 315 PHE B CE2 1 
ATOM 5283 C CZ  . PHE B 2 8   ? 152.949 158.547 193.638 1.00 71.41  ? 315 PHE B CZ  1 
ATOM 5284 N N   . LEU B 2 9   ? 150.201 162.726 188.508 1.00 67.77  ? 316 LEU B N   1 
ATOM 5285 C CA  . LEU B 2 9   ? 149.528 163.744 187.701 1.00 67.98  ? 316 LEU B CA  1 
ATOM 5286 C C   . LEU B 2 9   ? 148.021 163.662 187.808 1.00 68.42  ? 316 LEU B C   1 
ATOM 5287 O O   . LEU B 2 9   ? 147.376 162.867 187.110 1.00 68.90  ? 316 LEU B O   1 
ATOM 5288 C CB  . LEU B 2 9   ? 149.875 163.574 186.208 1.00 67.66  ? 316 LEU B CB  1 
ATOM 5289 C CG  . LEU B 2 9   ? 151.304 163.778 185.721 1.00 66.64  ? 316 LEU B CG  1 
ATOM 5290 C CD1 . LEU B 2 9   ? 151.426 163.415 184.256 1.00 66.87  ? 316 LEU B CD1 1 
ATOM 5291 C CD2 . LEU B 2 9   ? 151.721 165.202 185.985 1.00 65.86  ? 316 LEU B CD2 1 
ATOM 5292 N N   . SER B 2 10  ? 147.442 164.506 188.639 1.00 68.61  ? 317 SER B N   1 
ATOM 5293 C CA  . SER B 2 10  ? 146.000 164.507 188.780 1.00 69.04  ? 317 SER B CA  1 
ATOM 5294 C C   . SER B 2 10  ? 145.410 165.710 188.071 1.00 69.27  ? 317 SER B C   1 
ATOM 5295 O O   . SER B 2 10  ? 146.070 166.741 187.932 1.00 69.13  ? 317 SER B O   1 
ATOM 5296 C CB  . SER B 2 10  ? 145.620 164.541 190.251 1.00 68.91  ? 317 SER B CB  1 
ATOM 5297 O OG  . SER B 2 10  ? 146.372 165.537 190.909 1.00 69.46  ? 317 SER B OG  1 
ATOM 5298 N N   . GLN B 2 11  ? 144.164 165.575 187.627 1.00 69.74  ? 318 GLN B N   1 
ATOM 5299 C CA  . GLN B 2 11  ? 143.470 166.664 186.964 1.00 70.48  ? 318 GLN B CA  1 
ATOM 5300 C C   . GLN B 2 11  ? 143.554 167.880 187.896 1.00 70.81  ? 318 GLN B C   1 
ATOM 5301 O O   . GLN B 2 11  ? 143.974 168.969 187.490 1.00 70.97  ? 318 GLN B O   1 
ATOM 5302 C CB  . GLN B 2 11  ? 142.011 166.270 186.700 1.00 70.59  ? 318 GLN B CB  1 
ATOM 5303 C CG  . GLN B 2 11  ? 141.138 167.360 186.068 1.00 71.86  ? 318 GLN B CG  1 
ATOM 5304 C CD  . GLN B 2 11  ? 141.577 167.737 184.657 1.00 74.06  ? 318 GLN B CD  1 
ATOM 5305 O OE1 . GLN B 2 11  ? 142.224 168.769 184.454 1.00 75.24  ? 318 GLN B OE1 1 
ATOM 5306 N NE2 . GLN B 2 11  ? 141.229 166.901 183.677 1.00 74.10  ? 318 GLN B NE2 1 
ATOM 5307 N N   . GLU B 2 12  ? 143.191 167.653 189.157 1.00 71.14  ? 319 GLU B N   1 
ATOM 5308 C CA  . GLU B 2 12  ? 143.196 168.664 190.205 1.00 71.33  ? 319 GLU B CA  1 
ATOM 5309 C C   . GLU B 2 12  ? 144.526 169.422 190.353 1.00 71.04  ? 319 GLU B C   1 
ATOM 5310 O O   . GLU B 2 12  ? 144.532 170.645 190.510 1.00 70.92  ? 319 GLU B O   1 
ATOM 5311 C CB  . GLU B 2 12  ? 142.818 168.003 191.532 1.00 71.64  ? 319 GLU B CB  1 
ATOM 5312 C CG  . GLU B 2 12  ? 142.201 168.942 192.564 1.00 73.02  ? 319 GLU B CG  1 
ATOM 5313 C CD  . GLU B 2 12  ? 142.260 168.383 193.978 1.00 75.08  ? 319 GLU B CD  1 
ATOM 5314 O OE1 . GLU B 2 12  ? 143.095 167.484 194.238 1.00 75.83  ? 319 GLU B OE1 1 
ATOM 5315 O OE2 . GLU B 2 12  ? 141.480 168.853 194.837 1.00 76.10  ? 319 GLU B OE2 1 
ATOM 5316 N N   . ASP B 2 13  ? 145.640 168.698 190.304 1.00 70.74  ? 320 ASP B N   1 
ATOM 5317 C CA  . ASP B 2 13  ? 146.960 169.314 190.447 1.00 70.60  ? 320 ASP B CA  1 
ATOM 5318 C C   . ASP B 2 13  ? 147.412 170.108 189.225 1.00 70.38  ? 320 ASP B C   1 
ATOM 5319 O O   . ASP B 2 13  ? 148.039 171.165 189.361 1.00 70.13  ? 320 ASP B O   1 
ATOM 5320 C CB  . ASP B 2 13  ? 148.002 168.263 190.825 1.00 70.68  ? 320 ASP B CB  1 
ATOM 5321 C CG  . ASP B 2 13  ? 147.930 167.864 192.302 1.00 71.94  ? 320 ASP B CG  1 
ATOM 5322 O OD1 . ASP B 2 13  ? 146.944 168.206 193.001 1.00 72.34  ? 320 ASP B OD1 1 
ATOM 5323 O OD2 . ASP B 2 13  ? 148.876 167.200 192.767 1.00 73.09  ? 320 ASP B OD2 1 
ATOM 5324 N N   . VAL B 2 14  ? 147.090 169.600 188.034 1.00 70.27  ? 321 VAL B N   1 
ATOM 5325 C CA  . VAL B 2 14  ? 147.450 170.270 186.786 1.00 69.99  ? 321 VAL B CA  1 
ATOM 5326 C C   . VAL B 2 14  ? 146.788 171.645 186.754 1.00 69.96  ? 321 VAL B C   1 
ATOM 5327 O O   . VAL B 2 14  ? 147.437 172.654 186.464 1.00 69.89  ? 321 VAL B O   1 
ATOM 5328 C CB  . VAL B 2 14  ? 147.038 169.451 185.538 1.00 69.85  ? 321 VAL B CB  1 
ATOM 5329 C CG1 . VAL B 2 14  ? 147.300 170.241 184.278 1.00 69.52  ? 321 VAL B CG1 1 
ATOM 5330 C CG2 . VAL B 2 14  ? 147.793 168.141 185.481 1.00 69.79  ? 321 VAL B CG2 1 
ATOM 5331 N N   . GLU B 2 15  ? 145.500 171.674 187.084 1.00 69.81  ? 322 GLU B N   1 
ATOM 5332 C CA  . GLU B 2 15  ? 144.738 172.912 187.108 1.00 70.00  ? 322 GLU B CA  1 
ATOM 5333 C C   . GLU B 2 15  ? 145.382 173.934 188.036 1.00 69.65  ? 322 GLU B C   1 
ATOM 5334 O O   . GLU B 2 15  ? 145.505 175.106 187.686 1.00 69.51  ? 322 GLU B O   1 
ATOM 5335 C CB  . GLU B 2 15  ? 143.290 172.639 187.517 1.00 69.93  ? 322 GLU B CB  1 
ATOM 5336 C CG  . GLU B 2 15  ? 142.529 171.761 186.521 1.00 70.73  ? 322 GLU B CG  1 
ATOM 5337 C CD  . GLU B 2 15  ? 141.025 171.694 186.786 1.00 70.92  ? 322 GLU B CD  1 
ATOM 5338 O OE1 . GLU B 2 15  ? 140.604 171.723 187.970 1.00 71.22  ? 322 GLU B OE1 1 
ATOM 5339 O OE2 . GLU B 2 15  ? 140.264 171.600 185.791 1.00 72.03  ? 322 GLU B OE2 1 
ATOM 5340 N N   . ALA B 2 16  ? 145.814 173.469 189.206 1.00 69.65  ? 323 ALA B N   1 
ATOM 5341 C CA  . ALA B 2 16  ? 146.453 174.320 190.209 1.00 69.54  ? 323 ALA B CA  1 
ATOM 5342 C C   . ALA B 2 16  ? 147.781 174.915 189.733 1.00 69.46  ? 323 ALA B C   1 
ATOM 5343 O O   . ALA B 2 16  ? 148.038 176.101 189.918 1.00 69.76  ? 323 ALA B O   1 
ATOM 5344 C CB  . ALA B 2 16  ? 146.648 173.552 191.510 1.00 69.42  ? 323 ALA B CB  1 
ATOM 5345 N N   . VAL B 2 17  ? 148.614 174.093 189.116 1.00 69.22  ? 324 VAL B N   1 
ATOM 5346 C CA  . VAL B 2 17  ? 149.907 174.541 188.633 1.00 69.11  ? 324 VAL B CA  1 
ATOM 5347 C C   . VAL B 2 17  ? 149.835 175.431 187.371 1.00 69.19  ? 324 VAL B C   1 
ATOM 5348 O O   . VAL B 2 17  ? 150.743 176.227 187.106 1.00 69.42  ? 324 VAL B O   1 
ATOM 5349 C CB  . VAL B 2 17  ? 150.826 173.315 188.460 1.00 69.28  ? 324 VAL B CB  1 
ATOM 5350 C CG1 . VAL B 2 17  ? 151.820 173.490 187.324 1.00 69.28  ? 324 VAL B CG1 1 
ATOM 5351 C CG2 . VAL B 2 17  ? 151.533 173.016 189.780 1.00 69.17  ? 324 VAL B CG2 1 
ATOM 5352 N N   . SER B 2 18  ? 148.744 175.326 186.619 1.00 68.82  ? 325 SER B N   1 
ATOM 5353 C CA  . SER B 2 18  ? 148.573 176.116 185.401 1.00 68.52  ? 325 SER B CA  1 
ATOM 5354 C C   . SER B 2 18  ? 147.515 177.235 185.478 1.00 68.46  ? 325 SER B C   1 
ATOM 5355 O O   . SER B 2 18  ? 147.179 177.839 184.460 1.00 68.31  ? 325 SER B O   1 
ATOM 5356 C CB  . SER B 2 18  ? 148.272 175.180 184.231 1.00 68.50  ? 325 SER B CB  1 
ATOM 5357 O OG  . SER B 2 18  ? 147.107 174.417 184.483 1.00 68.31  ? 325 SER B OG  1 
ATOM 5358 N N   . ALA B 2 19  ? 147.013 177.517 186.680 1.00 68.50  ? 326 ALA B N   1 
ATOM 5359 C CA  . ALA B 2 19  ? 145.995 178.559 186.899 1.00 68.43  ? 326 ALA B CA  1 
ATOM 5360 C C   . ALA B 2 19  ? 146.447 179.943 186.426 1.00 68.47  ? 326 ALA B C   1 
ATOM 5361 O O   . ALA B 2 19  ? 145.629 180.753 185.977 1.00 68.60  ? 326 ALA B O   1 
ATOM 5362 C CB  . ALA B 2 19  ? 145.584 178.606 188.362 1.00 68.50  ? 326 ALA B CB  1 
ATOM 5363 N N   . ASN B 2 20  ? 147.750 180.199 186.540 1.00 68.26  ? 327 ASN B N   1 
ATOM 5364 C CA  . ASN B 2 20  ? 148.367 181.457 186.108 1.00 67.97  ? 327 ASN B CA  1 
ATOM 5365 C C   . ASN B 2 20  ? 149.866 181.272 185.870 1.00 67.80  ? 327 ASN B C   1 
ATOM 5366 O O   . ASN B 2 20  ? 150.408 180.185 186.110 1.00 67.90  ? 327 ASN B O   1 
ATOM 5367 C CB  . ASN B 2 20  ? 148.065 182.624 187.056 1.00 67.88  ? 327 ASN B CB  1 
ATOM 5368 C CG  . ASN B 2 20  ? 148.566 182.386 188.452 1.00 67.81  ? 327 ASN B CG  1 
ATOM 5369 O OD1 . ASN B 2 20  ? 149.745 182.583 188.747 1.00 67.97  ? 327 ASN B OD1 1 
ATOM 5370 N ND2 . ASN B 2 20  ? 147.668 181.970 189.331 1.00 67.67  ? 327 ASN B ND2 1 
ATOM 5371 N N   . ALA B 2 21  ? 150.519 182.325 185.383 1.00 67.53  ? 328 ALA B N   1 
ATOM 5372 C CA  . ALA B 2 21  ? 151.949 182.300 185.058 1.00 67.30  ? 328 ALA B CA  1 
ATOM 5373 C C   . ALA B 2 21  ? 152.885 181.902 186.199 1.00 67.14  ? 328 ALA B C   1 
ATOM 5374 O O   . ALA B 2 21  ? 153.931 181.303 185.953 1.00 67.14  ? 328 ALA B O   1 
ATOM 5375 C CB  . ALA B 2 21  ? 152.380 183.643 184.453 1.00 67.19  ? 328 ALA B CB  1 
ATOM 5376 N N   . THR B 2 22  ? 152.510 182.235 187.434 1.00 66.84  ? 329 THR B N   1 
ATOM 5377 C CA  . THR B 2 22  ? 153.325 181.930 188.609 1.00 66.60  ? 329 THR B CA  1 
ATOM 5378 C C   . THR B 2 22  ? 152.587 181.058 189.630 1.00 66.49  ? 329 THR B C   1 
ATOM 5379 O O   . THR B 2 22  ? 152.919 181.076 190.823 1.00 66.30  ? 329 THR B O   1 
ATOM 5380 C CB  . THR B 2 22  ? 153.783 183.220 189.330 1.00 66.63  ? 329 THR B CB  1 
ATOM 5381 O OG1 . THR B 2 22  ? 152.650 183.842 189.944 1.00 66.51  ? 329 THR B OG1 1 
ATOM 5382 C CG2 . THR B 2 22  ? 154.441 184.203 188.362 1.00 66.41  ? 329 THR B CG2 1 
ATOM 5383 N N   . ALA B 2 23  ? 151.589 180.307 189.161 1.00 66.14  ? 330 ALA B N   1 
ATOM 5384 C CA  . ALA B 2 23  ? 150.807 179.433 190.038 1.00 65.72  ? 330 ALA B CA  1 
ATOM 5385 C C   . ALA B 2 23  ? 151.674 178.331 190.634 1.00 65.62  ? 330 ALA B C   1 
ATOM 5386 O O   . ALA B 2 23  ? 151.554 178.021 191.824 1.00 65.63  ? 330 ALA B O   1 
ATOM 5387 C CB  . ALA B 2 23  ? 149.621 178.851 189.303 1.00 65.59  ? 330 ALA B CB  1 
ATOM 5388 N N   . ALA B 2 24  ? 152.554 177.759 189.810 1.00 65.44  ? 331 ALA B N   1 
ATOM 5389 C CA  . ALA B 2 24  ? 153.455 176.698 190.255 1.00 65.24  ? 331 ALA B CA  1 
ATOM 5390 C C   . ALA B 2 24  ? 154.367 177.165 191.391 1.00 65.13  ? 331 ALA B C   1 
ATOM 5391 O O   . ALA B 2 24  ? 154.447 176.513 192.431 1.00 65.17  ? 331 ALA B O   1 
ATOM 5392 C CB  . ALA B 2 24  ? 154.274 176.181 189.099 1.00 65.29  ? 331 ALA B CB  1 
ATOM 5393 N N   . THR B 2 25  ? 155.039 178.294 191.188 1.00 65.11  ? 332 THR B N   1 
ATOM 5394 C CA  . THR B 2 25  ? 155.940 178.870 192.181 1.00 65.18  ? 332 THR B CA  1 
ATOM 5395 C C   . THR B 2 25  ? 155.210 179.067 193.511 1.00 65.51  ? 332 THR B C   1 
ATOM 5396 O O   . THR B 2 25  ? 155.754 178.758 194.578 1.00 65.57  ? 332 THR B O   1 
ATOM 5397 C CB  . THR B 2 25  ? 156.544 180.191 191.673 1.00 65.09  ? 332 THR B CB  1 
ATOM 5398 O OG1 . THR B 2 25  ? 157.420 179.911 190.581 1.00 64.92  ? 332 THR B OG1 1 
ATOM 5399 C CG2 . THR B 2 25  ? 157.345 180.882 192.747 1.00 64.90  ? 332 THR B CG2 1 
ATOM 5400 N N   . THR B 2 26  ? 153.969 179.544 193.434 1.00 65.76  ? 333 THR B N   1 
ATOM 5401 C CA  . THR B 2 26  ? 153.145 179.758 194.615 1.00 66.07  ? 333 THR B CA  1 
ATOM 5402 C C   . THR B 2 26  ? 152.858 178.426 195.317 1.00 66.40  ? 333 THR B C   1 
ATOM 5403 O O   . THR B 2 26  ? 153.012 178.316 196.532 1.00 66.73  ? 333 THR B O   1 
ATOM 5404 C CB  . THR B 2 26  ? 151.816 180.447 194.262 1.00 65.97  ? 333 THR B CB  1 
ATOM 5405 O OG1 . THR B 2 26  ? 152.069 181.562 193.401 1.00 66.04  ? 333 THR B OG1 1 
ATOM 5406 C CG2 . THR B 2 26  ? 151.111 180.930 195.519 1.00 65.74  ? 333 THR B CG2 1 
ATOM 5407 N N   . VAL B 2 27  ? 152.452 177.418 194.550 1.00 66.65  ? 334 VAL B N   1 
ATOM 5408 C CA  . VAL B 2 27  ? 152.148 176.111 195.121 1.00 66.94  ? 334 VAL B CA  1 
ATOM 5409 C C   . VAL B 2 27  ? 153.351 175.533 195.850 1.00 67.46  ? 334 VAL B C   1 
ATOM 5410 O O   . VAL B 2 27  ? 153.230 175.103 197.009 1.00 67.50  ? 334 VAL B O   1 
ATOM 5411 C CB  . VAL B 2 27  ? 151.625 175.120 194.063 1.00 66.77  ? 334 VAL B CB  1 
ATOM 5412 C CG1 . VAL B 2 27  ? 151.630 173.696 194.597 1.00 66.40  ? 334 VAL B CG1 1 
ATOM 5413 C CG2 . VAL B 2 27  ? 150.226 175.503 193.639 1.00 66.92  ? 334 VAL B CG2 1 
ATOM 5414 N N   . LEU B 2 28  ? 154.504 175.549 195.181 1.00 68.00  ? 335 LEU B N   1 
ATOM 5415 C CA  . LEU B 2 28  ? 155.749 175.016 195.745 1.00 68.84  ? 335 LEU B CA  1 
ATOM 5416 C C   . LEU B 2 28  ? 156.290 175.782 196.964 1.00 69.39  ? 335 LEU B C   1 
ATOM 5417 O O   . LEU B 2 28  ? 156.896 175.177 197.846 1.00 69.00  ? 335 LEU B O   1 
ATOM 5418 C CB  . LEU B 2 28  ? 156.829 174.873 194.670 1.00 68.79  ? 335 LEU B CB  1 
ATOM 5419 C CG  . LEU B 2 28  ? 156.537 173.929 193.494 1.00 69.23  ? 335 LEU B CG  1 
ATOM 5420 C CD1 . LEU B 2 28  ? 157.527 174.147 192.349 1.00 67.74  ? 335 LEU B CD1 1 
ATOM 5421 C CD2 . LEU B 2 28  ? 156.534 172.469 193.943 1.00 69.83  ? 335 LEU B CD2 1 
ATOM 5422 N N   . ARG B 2 29  ? 156.083 177.100 197.006 1.00 70.26  ? 336 ARG B N   1 
ATOM 5423 C CA  . ARG B 2 29  ? 156.547 177.900 198.136 1.00 70.95  ? 336 ARG B CA  1 
ATOM 5424 C C   . ARG B 2 29  ? 155.649 177.655 199.326 1.00 71.38  ? 336 ARG B C   1 
ATOM 5425 O O   . ARG B 2 29  ? 156.139 177.501 200.451 1.00 71.62  ? 336 ARG B O   1 
ATOM 5426 C CB  . ARG B 2 29  ? 156.593 179.390 197.815 1.00 71.06  ? 336 ARG B CB  1 
ATOM 5427 C CG  . ARG B 2 29  ? 157.848 179.803 197.068 1.00 72.43  ? 336 ARG B CG  1 
ATOM 5428 C CD  . ARG B 2 29  ? 157.992 181.321 196.995 1.00 73.85  ? 336 ARG B CD  1 
ATOM 5429 N NE  . ARG B 2 29  ? 158.591 181.736 195.723 1.00 73.87  ? 336 ARG B NE  1 
ATOM 5430 C CZ  . ARG B 2 29  ? 158.784 182.999 195.352 1.00 74.34  ? 336 ARG B CZ  1 
ATOM 5431 N NH1 . ARG B 2 29  ? 158.438 183.994 196.160 1.00 74.94  ? 336 ARG B NH1 1 
ATOM 5432 N NH2 . ARG B 2 29  ? 159.335 183.272 194.172 1.00 74.12  ? 336 ARG B NH2 1 
ATOM 5433 N N   . GLN B 2 30  ? 154.339 177.593 199.084 1.00 71.72  ? 337 GLN B N   1 
ATOM 5434 C CA  . GLN B 2 30  ? 153.395 177.338 200.171 1.00 72.53  ? 337 GLN B CA  1 
ATOM 5435 C C   . GLN B 2 30  ? 153.651 175.974 200.823 1.00 72.68  ? 337 GLN B C   1 
ATOM 5436 O O   . GLN B 2 30  ? 153.326 175.758 201.994 1.00 72.75  ? 337 GLN B O   1 
ATOM 5437 C CB  . GLN B 2 30  ? 151.941 177.536 199.728 1.00 72.59  ? 337 GLN B CB  1 
ATOM 5438 C CG  . GLN B 2 30  ? 151.629 179.012 199.400 1.00 74.26  ? 337 GLN B CG  1 
ATOM 5439 C CD  . GLN B 2 30  ? 150.208 179.253 198.882 1.00 76.07  ? 337 GLN B CD  1 
ATOM 5440 O OE1 . GLN B 2 30  ? 149.573 178.355 198.327 1.00 77.67  ? 337 GLN B OE1 1 
ATOM 5441 N NE2 . GLN B 2 30  ? 149.702 180.471 199.081 1.00 76.02  ? 337 GLN B NE2 1 
ATOM 5442 N N   . LEU B 2 31  ? 154.281 175.079 200.067 1.00 73.02  ? 338 LEU B N   1 
ATOM 5443 C CA  . LEU B 2 31  ? 154.626 173.759 200.565 1.00 73.20  ? 338 LEU B CA  1 
ATOM 5444 C C   . LEU B 2 31  ? 155.964 173.821 201.296 1.00 73.50  ? 338 LEU B C   1 
ATOM 5445 O O   . LEU B 2 31  ? 156.153 173.111 202.279 1.00 73.74  ? 338 LEU B O   1 
ATOM 5446 C CB  . LEU B 2 31  ? 154.641 172.710 199.448 1.00 72.92  ? 338 LEU B CB  1 
ATOM 5447 C CG  . LEU B 2 31  ? 153.286 172.290 198.861 1.00 72.70  ? 338 LEU B CG  1 
ATOM 5448 C CD1 . LEU B 2 31  ? 153.479 171.271 197.757 1.00 72.50  ? 338 LEU B CD1 1 
ATOM 5449 C CD2 . LEU B 2 31  ? 152.312 171.752 199.903 1.00 71.79  ? 338 LEU B CD2 1 
ATOM 5450 N N   . ASP B 2 32  ? 156.874 174.678 200.829 1.00 73.91  ? 339 ASP B N   1 
ATOM 5451 C CA  . ASP B 2 32  ? 158.179 174.843 201.464 1.00 74.78  ? 339 ASP B CA  1 
ATOM 5452 C C   . ASP B 2 32  ? 157.946 175.394 202.863 1.00 75.27  ? 339 ASP B C   1 
ATOM 5453 O O   . ASP B 2 32  ? 158.618 175.007 203.819 1.00 75.30  ? 339 ASP B O   1 
ATOM 5454 C CB  . ASP B 2 32  ? 159.067 175.813 200.682 1.00 74.86  ? 339 ASP B CB  1 
ATOM 5455 C CG  . ASP B 2 32  ? 159.967 175.114 199.656 1.00 76.52  ? 339 ASP B CG  1 
ATOM 5456 O OD1 . ASP B 2 32  ? 159.932 173.867 199.542 1.00 78.06  ? 339 ASP B OD1 1 
ATOM 5457 O OD2 . ASP B 2 32  ? 160.721 175.824 198.951 1.00 77.56  ? 339 ASP B OD2 1 
ATOM 5458 N N   . MET B 2 33  ? 156.970 176.295 202.961 1.00 75.64  ? 340 MET B N   1 
ATOM 5459 C CA  . MET B 2 33  ? 156.605 176.930 204.213 1.00 76.01  ? 340 MET B CA  1 
ATOM 5460 C C   . MET B 2 33  ? 155.905 175.974 205.169 1.00 75.93  ? 340 MET B C   1 
ATOM 5461 O O   . MET B 2 33  ? 156.185 176.006 206.370 1.00 76.12  ? 340 MET B O   1 
ATOM 5462 C CB  . MET B 2 33  ? 155.757 178.176 203.956 1.00 75.85  ? 340 MET B CB  1 
ATOM 5463 C CG  . MET B 2 33  ? 156.546 179.309 203.312 1.00 76.38  ? 340 MET B CG  1 
ATOM 5464 S SD  . MET B 2 33  ? 155.615 180.847 203.098 1.00 77.30  ? 340 MET B SD  1 
ATOM 5465 C CE  . MET B 2 33  ? 155.584 181.504 204.783 1.00 77.38  ? 340 MET B CE  1 
ATOM 5466 N N   . GLU B 2 34  ? 155.023 175.115 204.653 1.00 75.91  ? 341 GLU B N   1 
ATOM 5467 C CA  . GLU B 2 34  ? 154.318 174.145 205.498 1.00 76.04  ? 341 GLU B CA  1 
ATOM 5468 C C   . GLU B 2 34  ? 155.376 173.231 206.117 1.00 75.69  ? 341 GLU B C   1 
ATOM 5469 O O   . GLU B 2 34  ? 155.278 172.837 207.281 1.00 75.46  ? 341 GLU B O   1 
ATOM 5470 C CB  . GLU B 2 34  ? 153.308 173.312 204.693 1.00 76.36  ? 341 GLU B CB  1 
ATOM 5471 C CG  . GLU B 2 34  ? 151.830 173.364 205.171 1.00 78.48  ? 341 GLU B CG  1 
ATOM 5472 C CD  . GLU B 2 34  ? 151.615 173.057 206.674 1.00 82.34  ? 341 GLU B CD  1 
ATOM 5473 O OE1 . GLU B 2 34  ? 152.124 172.021 207.175 1.00 83.46  ? 341 GLU B OE1 1 
ATOM 5474 O OE2 . GLU B 2 34  ? 150.909 173.847 207.360 1.00 83.01  ? 341 GLU B OE2 1 
ATOM 5475 N N   . LEU B 2 35  ? 156.404 172.933 205.328 1.00 75.37  ? 342 LEU B N   1 
ATOM 5476 C CA  . LEU B 2 35  ? 157.508 172.078 205.749 1.00 75.21  ? 342 LEU B CA  1 
ATOM 5477 C C   . LEU B 2 35  ? 158.314 172.654 206.916 1.00 74.76  ? 342 LEU B C   1 
ATOM 5478 O O   . LEU B 2 35  ? 158.615 171.937 207.880 1.00 74.68  ? 342 LEU B O   1 
ATOM 5479 C CB  . LEU B 2 35  ? 158.425 171.791 204.562 1.00 75.28  ? 342 LEU B CB  1 
ATOM 5480 C CG  . LEU B 2 35  ? 159.418 170.633 204.656 1.00 75.74  ? 342 LEU B CG  1 
ATOM 5481 C CD1 . LEU B 2 35  ? 158.741 169.362 205.141 1.00 76.71  ? 342 LEU B CD1 1 
ATOM 5482 C CD2 . LEU B 2 35  ? 160.062 170.406 203.300 1.00 76.04  ? 342 LEU B CD2 1 
ATOM 5483 N N   . VAL B 2 36  ? 158.660 173.938 206.821 1.00 74.23  ? 343 VAL B N   1 
ATOM 5484 C CA  . VAL B 2 36  ? 159.422 174.627 207.865 1.00 73.72  ? 343 VAL B CA  1 
ATOM 5485 C C   . VAL B 2 36  ? 158.561 174.685 209.131 1.00 73.33  ? 343 VAL B C   1 
ATOM 5486 O O   . VAL B 2 36  ? 159.043 174.460 210.245 1.00 73.04  ? 343 VAL B O   1 
ATOM 5487 C CB  . VAL B 2 36  ? 159.856 176.056 207.421 1.00 73.81  ? 343 VAL B CB  1 
ATOM 5488 C CG1 . VAL B 2 36  ? 160.612 176.781 208.546 1.00 73.94  ? 343 VAL B CG1 1 
ATOM 5489 C CG2 . VAL B 2 36  ? 160.716 175.996 206.167 1.00 73.36  ? 343 VAL B CG2 1 
ATOM 5490 N N   . SER B 2 37  ? 157.278 174.959 208.917 1.00 72.95  ? 344 SER B N   1 
ATOM 5491 C CA  . SER B 2 37  ? 156.269 175.057 209.960 1.00 72.66  ? 344 SER B CA  1 
ATOM 5492 C C   . SER B 2 37  ? 156.134 173.745 210.741 1.00 72.55  ? 344 SER B C   1 
ATOM 5493 O O   . SER B 2 37  ? 155.913 173.755 211.950 1.00 72.80  ? 344 SER B O   1 
ATOM 5494 C CB  . SER B 2 37  ? 154.939 175.456 209.315 1.00 72.59  ? 344 SER B CB  1 
ATOM 5495 O OG  . SER B 2 37  ? 153.894 175.554 210.249 1.00 72.70  ? 344 SER B OG  1 
ATOM 5496 N N   . VAL B 2 38  ? 156.286 172.623 210.051 1.00 72.31  ? 345 VAL B N   1 
ATOM 5497 C CA  . VAL B 2 38  ? 156.187 171.313 210.681 1.00 72.03  ? 345 VAL B CA  1 
ATOM 5498 C C   . VAL B 2 38  ? 157.508 170.937 211.358 1.00 71.93  ? 345 VAL B C   1 
ATOM 5499 O O   . VAL B 2 38  ? 157.510 170.292 212.401 1.00 71.53  ? 345 VAL B O   1 
ATOM 5500 C CB  . VAL B 2 38  ? 155.738 170.228 209.661 1.00 71.99  ? 345 VAL B CB  1 
ATOM 5501 C CG1 . VAL B 2 38  ? 155.922 168.826 210.210 1.00 71.75  ? 345 VAL B CG1 1 
ATOM 5502 C CG2 . VAL B 2 38  ? 154.279 170.431 209.304 1.00 72.53  ? 345 VAL B CG2 1 
ATOM 5503 N N   . LYS B 2 39  ? 158.628 171.340 210.765 1.00 71.97  ? 346 LYS B N   1 
ATOM 5504 C CA  . LYS B 2 39  ? 159.936 171.032 211.332 1.00 72.02  ? 346 LYS B CA  1 
ATOM 5505 C C   . LYS B 2 39  ? 160.167 171.748 212.653 1.00 72.00  ? 346 LYS B C   1 
ATOM 5506 O O   . LYS B 2 39  ? 160.662 171.135 213.600 1.00 72.13  ? 346 LYS B O   1 
ATOM 5507 C CB  . LYS B 2 39  ? 161.058 171.341 210.357 1.00 72.13  ? 346 LYS B CB  1 
ATOM 5508 C CG  . LYS B 2 39  ? 161.470 170.151 209.530 1.00 72.99  ? 346 LYS B CG  1 
ATOM 5509 C CD  . LYS B 2 39  ? 162.525 170.543 208.517 1.00 74.82  ? 346 LYS B CD  1 
ATOM 5510 C CE  . LYS B 2 39  ? 162.973 169.352 207.704 1.00 75.00  ? 346 LYS B CE  1 
ATOM 5511 N NZ  . LYS B 2 39  ? 163.650 169.803 206.463 1.00 75.98  ? 346 LYS B NZ  1 
ATOM 5512 N N   . ARG B 2 40  ? 159.801 173.028 212.731 1.00 71.89  ? 347 ARG B N   1 
ATOM 5513 C CA  . ARG B 2 40  ? 159.977 173.765 213.984 1.00 71.86  ? 347 ARG B CA  1 
ATOM 5514 C C   . ARG B 2 40  ? 159.027 173.214 215.052 1.00 71.56  ? 347 ARG B C   1 
ATOM 5515 O O   . ARG B 2 40  ? 159.347 173.211 216.244 1.00 71.58  ? 347 ARG B O   1 
ATOM 5516 C CB  . ARG B 2 40  ? 159.889 175.291 213.804 1.00 71.67  ? 347 ARG B CB  1 
ATOM 5517 C CG  . ARG B 2 40  ? 158.527 175.868 213.482 1.00 72.04  ? 347 ARG B CG  1 
ATOM 5518 C CD  . ARG B 2 40  ? 158.557 177.385 213.660 1.00 72.49  ? 347 ARG B CD  1 
ATOM 5519 N NE  . ARG B 2 40  ? 157.551 178.076 212.850 1.00 74.56  ? 347 ARG B NE  1 
ATOM 5520 C CZ  . ARG B 2 40  ? 157.802 178.701 211.700 1.00 75.39  ? 347 ARG B CZ  1 
ATOM 5521 N NH1 . ARG B 2 40  ? 159.036 178.739 211.206 1.00 76.08  ? 347 ARG B NH1 1 
ATOM 5522 N NH2 . ARG B 2 40  ? 156.813 179.293 211.037 1.00 75.73  ? 347 ARG B NH2 1 
ATOM 5523 N N   . GLN B 2 41  ? 157.889 172.691 214.600 1.00 71.17  ? 348 GLN B N   1 
ATOM 5524 C CA  . GLN B 2 41  ? 156.902 172.080 215.470 1.00 71.15  ? 348 GLN B CA  1 
ATOM 5525 C C   . GLN B 2 41  ? 157.517 170.810 216.059 1.00 70.64  ? 348 GLN B C   1 
ATOM 5526 O O   . GLN B 2 41  ? 157.237 170.445 217.196 1.00 70.75  ? 348 GLN B O   1 
ATOM 5527 C CB  . GLN B 2 41  ? 155.656 171.745 214.662 1.00 71.02  ? 348 GLN B CB  1 
ATOM 5528 C CG  . GLN B 2 41  ? 154.440 171.274 215.455 1.00 72.05  ? 348 GLN B CG  1 
ATOM 5529 C CD  . GLN B 2 41  ? 153.148 171.237 214.605 1.00 72.51  ? 348 GLN B CD  1 
ATOM 5530 O OE1 . GLN B 2 41  ? 152.037 171.339 215.146 1.00 74.82  ? 348 GLN B OE1 1 
ATOM 5531 N NE2 . GLN B 2 41  ? 153.291 171.107 213.279 1.00 72.04  ? 348 GLN B NE2 1 
ATOM 5532 N N   . ILE B 2 42  ? 158.375 170.150 215.288 1.00 70.19  ? 349 ILE B N   1 
ATOM 5533 C CA  . ILE B 2 42  ? 159.034 168.932 215.749 1.00 69.74  ? 349 ILE B CA  1 
ATOM 5534 C C   . ILE B 2 42  ? 160.077 169.244 216.819 1.00 69.61  ? 349 ILE B C   1 
ATOM 5535 O O   . ILE B 2 42  ? 160.081 168.619 217.867 1.00 69.34  ? 349 ILE B O   1 
ATOM 5536 C CB  . ILE B 2 42  ? 159.688 168.131 214.589 1.00 69.73  ? 349 ILE B CB  1 
ATOM 5537 C CG1 . ILE B 2 42  ? 158.621 167.405 213.769 1.00 69.66  ? 349 ILE B CG1 1 
ATOM 5538 C CG2 . ILE B 2 42  ? 160.714 167.122 215.120 1.00 69.42  ? 349 ILE B CG2 1 
ATOM 5539 C CD1 . ILE B 2 42  ? 159.107 166.893 212.412 1.00 69.37  ? 349 ILE B CD1 1 
ATOM 5540 N N   . GLN B 2 43  ? 160.956 170.204 216.539 1.00 69.60  ? 350 GLN B N   1 
ATOM 5541 C CA  . GLN B 2 43  ? 162.011 170.593 217.467 1.00 69.88  ? 350 GLN B CA  1 
ATOM 5542 C C   . GLN B 2 43  ? 161.427 171.025 218.804 1.00 69.33  ? 350 GLN B C   1 
ATOM 5543 O O   . GLN B 2 43  ? 161.990 170.747 219.868 1.00 69.35  ? 350 GLN B O   1 
ATOM 5544 C CB  . GLN B 2 43  ? 162.851 171.720 216.873 1.00 69.79  ? 350 GLN B CB  1 
ATOM 5545 C CG  . GLN B 2 43  ? 163.933 171.267 215.904 1.00 70.74  ? 350 GLN B CG  1 
ATOM 5546 C CD  . GLN B 2 43  ? 164.508 172.438 215.102 1.00 71.57  ? 350 GLN B CD  1 
ATOM 5547 O OE1 . GLN B 2 43  ? 164.698 172.347 213.871 1.00 74.28  ? 350 GLN B OE1 1 
ATOM 5548 N NE2 . GLN B 2 43  ? 164.767 173.556 215.791 1.00 73.15  ? 350 GLN B NE2 1 
ATOM 5549 N N   . ASN B 2 44  ? 160.277 171.687 218.727 1.00 68.80  ? 351 ASN B N   1 
ATOM 5550 C CA  . ASN B 2 44  ? 159.559 172.175 219.887 1.00 68.09  ? 351 ASN B CA  1 
ATOM 5551 C C   . ASN B 2 44  ? 159.124 171.045 220.794 1.00 67.78  ? 351 ASN B C   1 
ATOM 5552 O O   . ASN B 2 44  ? 159.370 171.077 222.003 1.00 68.13  ? 351 ASN B O   1 
ATOM 5553 C CB  . ASN B 2 44  ? 158.329 172.933 219.426 1.00 68.13  ? 351 ASN B CB  1 
ATOM 5554 C CG  . ASN B 2 44  ? 158.673 174.229 218.796 1.00 68.34  ? 351 ASN B CG  1 
ATOM 5555 O OD1 . ASN B 2 44  ? 159.734 174.791 219.040 1.00 69.21  ? 351 ASN B OD1 1 
ATOM 5556 N ND2 . ASN B 2 44  ? 157.778 174.725 217.964 1.00 70.38  ? 351 ASN B ND2 1 
ATOM 5557 N N   . ILE B 2 45  ? 158.466 170.051 220.207 1.00 67.24  ? 352 ILE B N   1 
ATOM 5558 C CA  . ILE B 2 45  ? 157.983 168.894 220.948 1.00 66.88  ? 352 ILE B CA  1 
ATOM 5559 C C   . ILE B 2 45  ? 159.154 168.062 221.473 1.00 67.04  ? 352 ILE B C   1 
ATOM 5560 O O   . ILE B 2 45  ? 159.117 167.587 222.613 1.00 66.98  ? 352 ILE B O   1 
ATOM 5561 C CB  . ILE B 2 45  ? 156.990 168.070 220.110 1.00 66.62  ? 352 ILE B CB  1 
ATOM 5562 C CG1 . ILE B 2 45  ? 155.741 168.915 219.854 1.00 66.42  ? 352 ILE B CG1 1 
ATOM 5563 C CG2 . ILE B 2 45  ? 156.633 166.764 220.811 1.00 66.20  ? 352 ILE B CG2 1 
ATOM 5564 C CD1 . ILE B 2 45  ? 154.781 168.352 218.846 1.00 66.84  ? 352 ILE B CD1 1 
ATOM 5565 N N   . LYS B 2 46  ? 160.201 167.939 220.658 1.00 66.99  ? 353 LYS B N   1 
ATOM 5566 C CA  . LYS B 2 46  ? 161.412 167.200 221.017 1.00 67.37  ? 353 LYS B CA  1 
ATOM 5567 C C   . LYS B 2 46  ? 161.991 167.779 222.306 1.00 67.33  ? 353 LYS B C   1 
ATOM 5568 O O   . LYS B 2 46  ? 162.375 167.045 223.223 1.00 67.34  ? 353 LYS B O   1 
ATOM 5569 C CB  . LYS B 2 46  ? 162.440 167.350 219.901 1.00 67.57  ? 353 LYS B CB  1 
ATOM 5570 C CG  . LYS B 2 46  ? 163.379 166.182 219.712 1.00 68.95  ? 353 LYS B CG  1 
ATOM 5571 C CD  . LYS B 2 46  ? 163.986 166.243 218.317 1.00 71.12  ? 353 LYS B CD  1 
ATOM 5572 C CE  . LYS B 2 46  ? 164.402 164.869 217.812 1.00 72.88  ? 353 LYS B CE  1 
ATOM 5573 N NZ  . LYS B 2 46  ? 164.654 164.906 216.339 1.00 72.77  ? 353 LYS B NZ  1 
ATOM 5574 N N   . GLN B 2 47  ? 162.035 169.107 222.352 1.00 67.14  ? 354 GLN B N   1 
ATOM 5575 C CA  . GLN B 2 47  ? 162.545 169.878 223.476 1.00 66.86  ? 354 GLN B CA  1 
ATOM 5576 C C   . GLN B 2 47  ? 161.711 169.644 224.757 1.00 66.29  ? 354 GLN B C   1 
ATOM 5577 O O   . GLN B 2 47  ? 162.259 169.516 225.869 1.00 65.82  ? 354 GLN B O   1 
ATOM 5578 C CB  . GLN B 2 47  ? 162.551 171.357 223.079 1.00 67.02  ? 354 GLN B CB  1 
ATOM 5579 C CG  . GLN B 2 47  ? 163.397 172.258 223.968 1.00 69.19  ? 354 GLN B CG  1 
ATOM 5580 C CD  . GLN B 2 47  ? 164.847 172.328 223.533 1.00 70.63  ? 354 GLN B CD  1 
ATOM 5581 O OE1 . GLN B 2 47  ? 165.150 172.321 222.329 1.00 69.92  ? 354 GLN B OE1 1 
ATOM 5582 N NE2 . GLN B 2 47  ? 165.758 172.410 224.515 1.00 69.96  ? 354 GLN B NE2 1 
ATOM 5583 N N   . THR B 2 48  ? 160.392 169.580 224.576 1.00 65.68  ? 355 THR B N   1 
ATOM 5584 C CA  . THR B 2 48  ? 159.436 169.350 225.654 1.00 65.07  ? 355 THR B CA  1 
ATOM 5585 C C   . THR B 2 48  ? 159.555 167.914 226.162 1.00 65.06  ? 355 THR B C   1 
ATOM 5586 O O   . THR B 2 48  ? 159.587 167.677 227.369 1.00 65.09  ? 355 THR B O   1 
ATOM 5587 C CB  . THR B 2 48  ? 158.004 169.644 225.173 1.00 64.89  ? 355 THR B CB  1 
ATOM 5588 O OG1 . THR B 2 48  ? 157.875 171.047 224.915 1.00 65.01  ? 355 THR B OG1 1 
ATOM 5589 C CG2 . THR B 2 48  ? 156.979 169.237 226.189 1.00 64.35  ? 355 THR B CG2 1 
ATOM 5590 N N   . ASN B 2 49  ? 159.641 166.958 225.238 1.00 65.10  ? 356 ASN B N   1 
ATOM 5591 C CA  . ASN B 2 49  ? 159.772 165.555 225.604 1.00 65.04  ? 356 ASN B CA  1 
ATOM 5592 C C   . ASN B 2 49  ? 161.075 165.296 226.357 1.00 65.45  ? 356 ASN B C   1 
ATOM 5593 O O   . ASN B 2 49  ? 161.114 164.498 227.292 1.00 65.43  ? 356 ASN B O   1 
ATOM 5594 C CB  . ASN B 2 49  ? 159.676 164.657 224.377 1.00 64.63  ? 356 ASN B CB  1 
ATOM 5595 C CG  . ASN B 2 49  ? 158.244 164.448 223.906 1.00 64.08  ? 356 ASN B CG  1 
ATOM 5596 O OD1 . ASN B 2 49  ? 157.285 164.748 224.617 1.00 62.00  ? 356 ASN B OD1 1 
ATOM 5597 N ND2 . ASN B 2 49  ? 158.099 163.920 222.690 1.00 64.69  ? 356 ASN B ND2 1 
ATOM 5598 N N   . SER B 2 50  ? 162.128 166.001 225.951 1.00 65.96  ? 357 SER B N   1 
ATOM 5599 C CA  . SER B 2 50  ? 163.442 165.881 226.569 1.00 66.64  ? 357 SER B CA  1 
ATOM 5600 C C   . SER B 2 50  ? 163.383 166.279 228.045 1.00 66.97  ? 357 SER B C   1 
ATOM 5601 O O   . SER B 2 50  ? 164.019 165.652 228.896 1.00 67.20  ? 357 SER B O   1 
ATOM 5602 C CB  . SER B 2 50  ? 164.450 166.739 225.803 1.00 66.71  ? 357 SER B CB  1 
ATOM 5603 O OG  . SER B 2 50  ? 165.678 166.820 226.495 1.00 67.76  ? 357 SER B OG  1 
ATOM 5604 N N   . ALA B 2 51  ? 162.593 167.309 228.338 1.00 67.38  ? 358 ALA B N   1 
ATOM 5605 C CA  . ALA B 2 51  ? 162.405 167.794 229.692 1.00 67.52  ? 358 ALA B CA  1 
ATOM 5606 C C   . ALA B 2 51  ? 161.594 166.778 230.488 1.00 68.13  ? 358 ALA B C   1 
ATOM 5607 O O   . ALA B 2 51  ? 161.954 166.457 231.620 1.00 68.81  ? 358 ALA B O   1 
ATOM 5608 C CB  . ALA B 2 51  ? 161.721 169.146 229.687 1.00 67.12  ? 358 ALA B CB  1 
ATOM 5609 N N   . LEU B 2 52  ? 160.513 166.259 229.905 1.00 68.80  ? 359 LEU B N   1 
ATOM 5610 C CA  . LEU B 2 52  ? 159.678 165.266 230.602 1.00 69.43  ? 359 LEU B CA  1 
ATOM 5611 C C   . LEU B 2 52  ? 160.463 163.998 230.936 1.00 70.22  ? 359 LEU B C   1 
ATOM 5612 O O   . LEU B 2 52  ? 160.256 163.400 231.993 1.00 70.18  ? 359 LEU B O   1 
ATOM 5613 C CB  . LEU B 2 52  ? 158.409 164.924 229.815 1.00 69.19  ? 359 LEU B CB  1 
ATOM 5614 C CG  . LEU B 2 52  ? 157.362 166.028 229.645 1.00 69.25  ? 359 LEU B CG  1 
ATOM 5615 C CD1 . LEU B 2 52  ? 156.450 165.743 228.468 1.00 69.73  ? 359 LEU B CD1 1 
ATOM 5616 C CD2 . LEU B 2 52  ? 156.543 166.212 230.890 1.00 69.42  ? 359 LEU B CD2 1 
ATOM 5617 N N   . LYS B 2 53  ? 161.373 163.605 230.045 1.00 71.27  ? 360 LYS B N   1 
ATOM 5618 C CA  . LYS B 2 53  ? 162.211 162.426 230.264 1.00 72.28  ? 360 LYS B CA  1 
ATOM 5619 C C   . LYS B 2 53  ? 163.167 162.670 231.438 1.00 73.19  ? 360 LYS B C   1 
ATOM 5620 O O   . LYS B 2 53  ? 163.451 161.757 232.219 1.00 72.95  ? 360 LYS B O   1 
ATOM 5621 C CB  . LYS B 2 53  ? 162.996 162.069 229.000 1.00 72.03  ? 360 LYS B CB  1 
ATOM 5622 C CG  . LYS B 2 53  ? 162.247 161.155 228.042 1.00 71.95  ? 360 LYS B CG  1 
ATOM 5623 C CD  . LYS B 2 53  ? 162.825 161.202 226.626 1.00 71.81  ? 360 LYS B CD  1 
ATOM 5624 C CE  . LYS B 2 53  ? 164.133 160.426 226.509 1.00 71.86  ? 360 LYS B CE  1 
ATOM 5625 N NZ  . LYS B 2 53  ? 164.800 160.668 225.201 1.00 70.90  ? 360 LYS B NZ  1 
ATOM 5626 N N   . GLU B 2 54  ? 163.640 163.912 231.553 1.00 74.51  ? 361 GLU B N   1 
ATOM 5627 C CA  . GLU B 2 54  ? 164.560 164.310 232.614 1.00 75.84  ? 361 GLU B CA  1 
ATOM 5628 C C   . GLU B 2 54  ? 163.910 164.234 233.990 1.00 76.66  ? 361 GLU B C   1 
ATOM 5629 O O   . GLU B 2 54  ? 164.605 164.100 234.996 1.00 76.83  ? 361 GLU B O   1 
ATOM 5630 C CB  . GLU B 2 54  ? 165.125 165.705 232.357 1.00 75.93  ? 361 GLU B CB  1 
ATOM 5631 C CG  . GLU B 2 54  ? 166.545 165.877 232.872 1.00 76.88  ? 361 GLU B CG  1 
ATOM 5632 C CD  . GLU B 2 54  ? 166.896 167.323 233.181 1.00 77.92  ? 361 GLU B CD  1 
ATOM 5633 O OE1 . GLU B 2 54  ? 167.130 167.625 234.377 1.00 78.33  ? 361 GLU B OE1 1 
ATOM 5634 O OE2 . GLU B 2 54  ? 166.934 168.151 232.242 1.00 77.02  ? 361 GLU B OE2 1 
ATOM 5635 N N   . LYS B 2 55  ? 162.579 164.296 234.022 1.00 77.69  ? 362 LYS B N   1 
ATOM 5636 C CA  . LYS B 2 55  ? 161.824 164.194 235.270 1.00 78.64  ? 362 LYS B CA  1 
ATOM 5637 C C   . LYS B 2 55  ? 161.622 162.745 235.666 1.00 79.20  ? 362 LYS B C   1 
ATOM 5638 O O   . LYS B 2 55  ? 161.415 162.445 236.836 1.00 79.97  ? 362 LYS B O   1 
ATOM 5639 C CB  . LYS B 2 55  ? 160.461 164.864 235.155 1.00 78.60  ? 362 LYS B CB  1 
ATOM 5640 C CG  . LYS B 2 55  ? 160.471 166.339 235.474 1.00 79.87  ? 362 LYS B CG  1 
ATOM 5641 C CD  . LYS B 2 55  ? 159.099 166.941 235.250 1.00 81.71  ? 362 LYS B CD  1 
ATOM 5642 C CE  . LYS B 2 55  ? 159.143 168.452 235.307 1.00 82.74  ? 362 LYS B CE  1 
ATOM 5643 N NZ  . LYS B 2 55  ? 158.313 169.011 234.208 1.00 83.91  ? 362 LYS B NZ  1 
ATOM 5644 N N   . LEU B 2 56  ? 161.663 161.844 234.697 1.00 79.97  ? 363 LEU B N   1 
ATOM 5645 C CA  . LEU B 2 56  ? 161.486 160.429 234.992 1.00 80.74  ? 363 LEU B CA  1 
ATOM 5646 C C   . LEU B 2 56  ? 162.828 159.756 235.260 1.00 81.60  ? 363 LEU B C   1 
ATOM 5647 O O   . LEU B 2 56  ? 162.893 158.532 235.404 1.00 81.95  ? 363 LEU B O   1 
ATOM 5648 C CB  . LEU B 2 56  ? 160.756 159.714 233.860 1.00 80.55  ? 363 LEU B CB  1 
ATOM 5649 C CG  . LEU B 2 56  ? 159.369 160.200 233.454 1.00 80.40  ? 363 LEU B CG  1 
ATOM 5650 C CD1 . LEU B 2 56  ? 158.953 159.460 232.199 1.00 80.71  ? 363 LEU B CD1 1 
ATOM 5651 C CD2 . LEU B 2 56  ? 158.351 159.996 234.551 1.00 78.95  ? 363 LEU B CD2 1 
ATOM 5652 N N   . ASP B 2 57  ? 163.891 160.555 235.324 1.00 82.41  ? 364 ASP B N   1 
ATOM 5653 C CA  . ASP B 2 57  ? 165.227 160.034 235.587 1.00 83.20  ? 364 ASP B CA  1 
ATOM 5654 C C   . ASP B 2 57  ? 165.231 159.276 236.914 1.00 83.53  ? 364 ASP B C   1 
ATOM 5655 O O   . ASP B 2 57  ? 164.924 159.837 237.971 1.00 83.51  ? 364 ASP B O   1 
ATOM 5656 C CB  . ASP B 2 57  ? 166.252 161.165 235.614 1.00 83.52  ? 364 ASP B CB  1 
ATOM 5657 C CG  . ASP B 2 57  ? 167.668 160.660 235.845 1.00 84.28  ? 364 ASP B CG  1 
ATOM 5658 O OD1 . ASP B 2 57  ? 168.317 160.237 234.862 1.00 84.75  ? 364 ASP B OD1 1 
ATOM 5659 O OD2 . ASP B 2 57  ? 168.130 160.694 237.009 1.00 84.73  ? 364 ASP B OD2 1 
ATOM 5660 N N   . GLY B 2 58  ? 165.569 157.994 236.838 1.00 83.89  ? 365 GLY B N   1 
ATOM 5661 C CA  . GLY B 2 58  ? 165.606 157.126 238.003 1.00 84.18  ? 365 GLY B CA  1 
ATOM 5662 C C   . GLY B 2 58  ? 164.411 156.195 238.008 1.00 84.50  ? 365 GLY B C   1 
ATOM 5663 O O   . GLY B 2 58  ? 164.366 155.233 238.783 1.00 84.72  ? 365 GLY B O   1 
ATOM 5664 N N   . GLY B 2 59  ? 163.444 156.479 237.134 1.00 84.55  ? 366 GLY B N   1 
ATOM 5665 C CA  . GLY B 2 59  ? 162.225 155.680 237.027 1.00 84.72  ? 366 GLY B CA  1 
ATOM 5666 C C   . GLY B 2 59  ? 161.496 155.634 238.357 1.00 84.98  ? 366 GLY B C   1 
ATOM 5667 O O   . GLY B 2 59  ? 161.450 156.627 239.096 1.00 84.94  ? 366 GLY B O   1 
ATOM 5668 N N   . ILE B 2 60  ? 160.941 154.470 238.673 1.00 85.10  ? 367 ILE B N   1 
ATOM 5669 C CA  . ILE B 2 60  ? 160.226 154.284 239.927 1.00 85.08  ? 367 ILE B CA  1 
ATOM 5670 C C   . ILE B 2 60  ? 160.925 153.239 240.814 1.00 85.78  ? 367 ILE B C   1 
ATOM 5671 O O   . ILE B 2 60  ? 160.288 152.567 241.621 1.00 85.76  ? 367 ILE B O   1 
ATOM 5672 C CB  . ILE B 2 60  ? 158.741 153.909 239.686 1.00 84.73  ? 367 ILE B CB  1 
ATOM 5673 C CG1 . ILE B 2 60  ? 158.623 152.667 238.800 1.00 83.91  ? 367 ILE B CG1 1 
ATOM 5674 C CG2 . ILE B 2 60  ? 157.972 155.097 239.115 1.00 83.94  ? 367 ILE B CG2 1 
ATOM 5675 C CD1 . ILE B 2 60  ? 157.283 151.965 238.905 1.00 82.82  ? 367 ILE B CD1 1 
ATOM 5676 N N   . GLU B 2 61  ? 162.243 153.119 240.665 1.00 86.64  ? 368 GLU B N   1 
ATOM 5677 C CA  . GLU B 2 61  ? 163.030 152.145 241.433 1.00 87.55  ? 368 GLU B CA  1 
ATOM 5678 C C   . GLU B 2 61  ? 163.003 152.322 242.951 1.00 87.94  ? 368 GLU B C   1 
ATOM 5679 O O   . GLU B 2 61  ? 162.778 151.345 243.665 1.00 87.95  ? 368 GLU B O   1 
ATOM 5680 C CB  . GLU B 2 61  ? 164.474 152.032 240.912 1.00 87.65  ? 368 GLU B CB  1 
ATOM 5681 C CG  . GLU B 2 61  ? 164.592 151.555 239.454 1.00 88.63  ? 368 GLU B CG  1 
ATOM 5682 C CD  . GLU B 2 61  ? 163.541 150.509 239.077 1.00 89.63  ? 368 GLU B CD  1 
ATOM 5683 O OE1 . GLU B 2 61  ? 163.514 149.420 239.699 1.00 89.82  ? 368 GLU B OE1 1 
ATOM 5684 O OE2 . GLU B 2 61  ? 162.732 150.781 238.158 1.00 89.62  ? 368 GLU B OE2 1 
ATOM 5685 N N   . PRO B 2 62  ? 163.210 153.560 243.449 1.00 88.46  ? 369 PRO B N   1 
ATOM 5686 C CA  . PRO B 2 62  ? 163.249 153.716 244.902 1.00 88.88  ? 369 PRO B CA  1 
ATOM 5687 C C   . PRO B 2 62  ? 161.877 153.551 245.554 1.00 89.26  ? 369 PRO B C   1 
ATOM 5688 O O   . PRO B 2 62  ? 161.784 153.466 246.785 1.00 89.57  ? 369 PRO B O   1 
ATOM 5689 C CB  . PRO B 2 62  ? 163.750 155.157 245.094 1.00 88.97  ? 369 PRO B CB  1 
ATOM 5690 C CG  . PRO B 2 62  ? 164.231 155.611 243.735 1.00 88.76  ? 369 PRO B CG  1 
ATOM 5691 C CD  . PRO B 2 62  ? 163.404 154.850 242.765 1.00 88.44  ? 369 PRO B CD  1 
ATOM 5692 N N   . TYR B 2 63  ? 160.832 153.483 244.731 1.00 89.38  ? 370 TYR B N   1 
ATOM 5693 C CA  . TYR B 2 63  ? 159.465 153.346 245.221 1.00 89.74  ? 370 TYR B CA  1 
ATOM 5694 C C   . TYR B 2 63  ? 158.860 151.953 245.109 1.00 90.30  ? 370 TYR B C   1 
ATOM 5695 O O   . TYR B 2 63  ? 157.679 151.761 245.397 1.00 90.28  ? 370 TYR B O   1 
ATOM 5696 C CB  . TYR B 2 63  ? 158.561 154.365 244.530 1.00 89.64  ? 370 TYR B CB  1 
ATOM 5697 C CG  . TYR B 2 63  ? 159.163 155.746 244.466 1.00 89.27  ? 370 TYR B CG  1 
ATOM 5698 C CD1 . TYR B 2 63  ? 159.414 156.468 245.629 1.00 88.74  ? 370 TYR B CD1 1 
ATOM 5699 C CD2 . TYR B 2 63  ? 159.489 156.324 243.246 1.00 88.65  ? 370 TYR B CD2 1 
ATOM 5700 C CE1 . TYR B 2 63  ? 159.970 157.723 245.581 1.00 89.04  ? 370 TYR B CE1 1 
ATOM 5701 C CE2 . TYR B 2 63  ? 160.040 157.591 243.186 1.00 88.70  ? 370 TYR B CE2 1 
ATOM 5702 C CZ  . TYR B 2 63  ? 160.278 158.282 244.355 1.00 89.41  ? 370 TYR B CZ  1 
ATOM 5703 O OH  . TYR B 2 63  ? 160.826 159.535 244.309 1.00 90.01  ? 370 TYR B OH  1 
ATOM 5704 N N   . ARG B 2 64  ? 159.656 150.979 244.692 1.00 91.32  ? 371 ARG B N   1 
ATOM 5705 C CA  . ARG B 2 64  ? 159.142 149.622 244.571 1.00 92.47  ? 371 ARG B CA  1 
ATOM 5706 C C   . ARG B 2 64  ? 159.257 148.852 245.875 1.00 92.92  ? 371 ARG B C   1 
ATOM 5707 O O   . ARG B 2 64  ? 160.235 148.994 246.616 1.00 92.68  ? 371 ARG B O   1 
ATOM 5708 C CB  . ARG B 2 64  ? 159.815 148.858 243.430 1.00 92.69  ? 371 ARG B CB  1 
ATOM 5709 C CG  . ARG B 2 64  ? 158.911 148.691 242.223 1.00 93.62  ? 371 ARG B CG  1 
ATOM 5710 C CD  . ARG B 2 64  ? 159.501 147.744 241.189 1.00 95.09  ? 371 ARG B CD  1 
ATOM 5711 N NE  . ARG B 2 64  ? 159.045 148.094 239.843 1.00 95.72  ? 371 ARG B NE  1 
ATOM 5712 C CZ  . ARG B 2 64  ? 159.670 148.949 239.038 1.00 95.67  ? 371 ARG B CZ  1 
ATOM 5713 N NH1 . ARG B 2 64  ? 160.790 149.545 239.427 1.00 95.45  ? 371 ARG B NH1 1 
ATOM 5714 N NH2 . ARG B 2 64  ? 159.176 149.209 237.840 1.00 95.83  ? 371 ARG B NH2 1 
ATOM 5715 N N   . LEU B 2 65  ? 158.242 148.037 246.142 1.00 93.71  ? 372 LEU B N   1 
ATOM 5716 C CA  . LEU B 2 65  ? 158.198 147.227 247.350 1.00 94.57  ? 372 LEU B CA  1 
ATOM 5717 C C   . LEU B 2 65  ? 158.354 145.754 247.013 1.00 95.15  ? 372 LEU B C   1 
ATOM 5718 O O   . LEU B 2 65  ? 157.733 145.275 246.062 1.00 95.12  ? 372 LEU B O   1 
ATOM 5719 C CB  . LEU B 2 65  ? 156.873 147.428 248.096 1.00 94.60  ? 372 LEU B CB  1 
ATOM 5720 C CG  . LEU B 2 65  ? 156.429 148.823 248.550 1.00 94.47  ? 372 LEU B CG  1 
ATOM 5721 C CD1 . LEU B 2 65  ? 155.012 148.734 249.087 1.00 94.08  ? 372 LEU B CD1 1 
ATOM 5722 C CD2 . LEU B 2 65  ? 157.380 149.432 249.583 1.00 94.01  ? 372 LEU B CD2 1 
ATOM 5723 N N   . PRO B 2 66  ? 159.182 145.033 247.795 1.00 95.84  ? 373 PRO B N   1 
ATOM 5724 C CA  . PRO B 2 66  ? 159.257 143.572 247.722 1.00 96.42  ? 373 PRO B CA  1 
ATOM 5725 C C   . PRO B 2 66  ? 157.870 142.921 247.671 1.00 97.06  ? 373 PRO B C   1 
ATOM 5726 O O   . PRO B 2 66  ? 156.883 143.516 248.115 1.00 97.13  ? 373 PRO B O   1 
ATOM 5727 C CB  . PRO B 2 66  ? 159.969 143.202 249.024 1.00 96.36  ? 373 PRO B CB  1 
ATOM 5728 C CG  . PRO B 2 66  ? 160.861 144.361 249.296 1.00 96.16  ? 373 PRO B CG  1 
ATOM 5729 C CD  . PRO B 2 66  ? 160.131 145.582 248.784 1.00 95.93  ? 373 PRO B CD  1 
ATOM 5730 N N   . GLU B 2 67  ? 157.799 141.711 247.125 1.00 97.80  ? 374 GLU B N   1 
ATOM 5731 C CA  . GLU B 2 67  ? 156.528 140.999 247.019 1.00 98.60  ? 374 GLU B CA  1 
ATOM 5732 C C   . GLU B 2 67  ? 156.260 140.112 248.238 1.00 98.63  ? 374 GLU B C   1 
ATOM 5733 O O   . GLU B 2 67  ? 157.160 139.414 248.714 1.00 98.69  ? 374 GLU B O   1 
ATOM 5734 C CB  . GLU B 2 67  ? 156.473 140.185 245.717 1.00 98.91  ? 374 GLU B CB  1 
ATOM 5735 C CG  . GLU B 2 67  ? 155.051 139.919 245.197 1.00 100.74 ? 374 GLU B CG  1 
ATOM 5736 C CD  . GLU B 2 67  ? 154.248 141.202 244.932 1.00 103.21 ? 374 GLU B CD  1 
ATOM 5737 O OE1 . GLU B 2 67  ? 152.999 141.151 245.025 1.00 104.04 ? 374 GLU B OE1 1 
ATOM 5738 O OE2 . GLU B 2 67  ? 154.857 142.260 244.634 1.00 104.10 ? 374 GLU B OE2 1 
ATOM 5739 N N   . VAL B 2 68  ? 155.021 140.153 248.734 1.00 98.67  ? 375 VAL B N   1 
ATOM 5740 C CA  . VAL B 2 68  ? 154.607 139.358 249.899 1.00 98.55  ? 375 VAL B CA  1 
ATOM 5741 C C   . VAL B 2 68  ? 154.119 137.985 249.415 1.00 98.19  ? 375 VAL B C   1 
ATOM 5742 O O   . VAL B 2 68  ? 152.911 137.735 249.314 1.00 98.27  ? 375 VAL B O   1 
ATOM 5743 C CB  . VAL B 2 68  ? 153.506 140.073 250.760 1.00 98.80  ? 375 VAL B CB  1 
ATOM 5744 C CG1 . VAL B 2 68  ? 153.487 139.509 252.190 1.00 99.05  ? 375 VAL B CG1 1 
ATOM 5745 C CG2 . VAL B 2 68  ? 153.712 141.594 250.789 1.00 98.79  ? 375 VAL B CG2 1 
ATOM 5746 N N   . ILE B 2 69  ? 155.078 137.113 249.109 1.00 97.57  ? 376 ILE B N   1 
ATOM 5747 C CA  . ILE B 2 69  ? 154.810 135.761 248.611 1.00 96.99  ? 376 ILE B CA  1 
ATOM 5748 C C   . ILE B 2 69  ? 154.335 134.807 249.714 1.00 96.47  ? 376 ILE B C   1 
ATOM 5749 O O   . ILE B 2 69  ? 155.129 134.364 250.549 1.00 96.46  ? 376 ILE B O   1 
ATOM 5750 C CB  . ILE B 2 69  ? 156.071 135.162 247.902 1.00 97.11  ? 376 ILE B CB  1 
ATOM 5751 C CG1 . ILE B 2 69  ? 156.644 136.154 246.873 1.00 97.21  ? 376 ILE B CG1 1 
ATOM 5752 C CG2 . ILE B 2 69  ? 155.756 133.795 247.267 1.00 97.00  ? 376 ILE B CG2 1 
ATOM 5753 C CD1 . ILE B 2 69  ? 158.147 135.994 246.593 1.00 97.07  ? 376 ILE B CD1 1 
ATOM 5754 N N   . SER C 3 1   ? 177.120 122.953 166.845 1.00 40.76  ? 257 SER C N   1 
ATOM 5755 C CA  . SER C 3 1   ? 177.145 121.562 166.320 1.00 37.76  ? 257 SER C CA  1 
ATOM 5756 C C   . SER C 3 1   ? 175.827 121.253 165.605 1.00 31.35  ? 257 SER C C   1 
ATOM 5757 O O   . SER C 3 1   ? 174.863 122.023 165.785 1.00 28.06  ? 257 SER C O   1 
ATOM 5758 C CB  . SER C 3 1   ? 177.409 120.573 167.424 1.00 40.31  ? 257 SER C CB  1 
ATOM 5759 O OG  . SER C 3 1   ? 178.651 120.841 168.057 1.00 40.70  ? 257 SER C OG  1 
ATOM 5760 N N   . ALA C 3 2   ? 175.792 120.169 164.823 1.00 28.93  ? 258 ALA C N   1 
ATOM 5761 C CA  . ALA C 3 2   ? 174.540 119.765 164.142 1.00 25.03  ? 258 ALA C CA  1 
ATOM 5762 C C   . ALA C 3 2   ? 173.479 119.450 165.199 1.00 18.32  ? 258 ALA C C   1 
ATOM 5763 O O   . ALA C 3 2   ? 172.355 119.975 165.078 1.00 19.64  ? 258 ALA C O   1 
ATOM 5764 C CB  . ALA C 3 2   ? 174.799 118.579 163.247 1.00 28.97  ? 258 ALA C CB  1 
ATOM 5765 N N   . HIS C 3 3   ? 173.835 118.642 166.203 1.00 12.75  ? 259 HIS C N   1 
ATOM 5766 C CA  . HIS C 3 3   ? 172.889 118.316 167.303 1.00 10.17  ? 259 HIS C CA  1 
ATOM 5767 C C   . HIS C 3 3   ? 172.397 119.610 167.950 1.00 9.61   ? 259 HIS C C   1 
ATOM 5768 O O   . HIS C 3 3   ? 171.390 119.554 168.684 1.00 10.94  ? 259 HIS C O   1 
ATOM 5769 C CB  . HIS C 3 3   ? 173.562 117.416 168.346 1.00 11.09  ? 259 HIS C CB  1 
ATOM 5770 C CG  . HIS C 3 3   ? 173.942 116.066 167.840 1.00 12.66  ? 259 HIS C CG  1 
ATOM 5771 N ND1 . HIS C 3 3   ? 173.396 114.906 168.353 1.00 13.35  ? 259 HIS C ND1 1 
ATOM 5772 C CD2 . HIS C 3 3   ? 174.809 115.685 166.877 1.00 16.07  ? 259 HIS C CD2 1 
ATOM 5773 C CE1 . HIS C 3 3   ? 173.914 113.867 167.731 1.00 14.21  ? 259 HIS C CE1 1 
ATOM 5774 N NE2 . HIS C 3 3   ? 174.781 114.318 166.817 1.00 16.07  ? 259 HIS C NE2 1 
ATOM 5775 N N   . LYS C 3 4   ? 173.082 120.728 167.690 1.00 10.25  ? 260 LYS C N   1 
ATOM 5776 C CA  . LYS C 3 4   ? 172.716 121.980 168.335 1.00 10.64  ? 260 LYS C CA  1 
ATOM 5777 C C   . LYS C 3 4   ? 171.813 122.812 167.443 1.00 10.84  ? 260 LYS C C   1 
ATOM 5778 O O   . LYS C 3 4   ? 171.989 122.858 166.221 1.00 11.85  ? 260 LYS C O   1 
ATOM 5779 C CB  . LYS C 3 4   ? 173.973 122.774 168.665 1.00 12.78  ? 260 LYS C CB  1 
ATOM 5780 C CG  . LYS C 3 4   ? 174.851 122.126 169.715 1.00 14.57  ? 260 LYS C CG  1 
ATOM 5781 C CD  . LYS C 3 4   ? 176.106 122.964 169.972 1.00 20.63  ? 260 LYS C CD  1 
ATOM 5782 C CE  . LYS C 3 4   ? 177.188 122.180 170.702 1.00 28.91  ? 260 LYS C CE  1 
ATOM 5783 N NZ  . LYS C 3 4   ? 176.857 121.958 172.130 1.00 33.96  ? 260 LYS C NZ  1 
ATOM 5784 N N   . LEU C 3 5   ? 170.872 123.511 168.077 1.00 10.23  ? 261 LEU C N   1 
ATOM 5785 C CA  . LEU C 3 5   ? 169.918 124.388 167.409 1.00 10.88  ? 261 LEU C CA  1 
ATOM 5786 C C   . LEU C 3 5   ? 169.966 125.786 168.003 1.00 9.72   ? 261 LEU C C   1 
ATOM 5787 O O   . LEU C 3 5   ? 170.284 125.979 169.185 1.00 10.76  ? 261 LEU C O   1 
ATOM 5788 C CB  . LEU C 3 5   ? 168.491 123.896 167.571 1.00 13.65  ? 261 LEU C CB  1 
ATOM 5789 C CG  . LEU C 3 5   ? 168.195 122.518 167.002 1.00 16.03  ? 261 LEU C CG  1 
ATOM 5790 C CD1 . LEU C 3 5   ? 166.709 122.209 167.062 1.00 18.70  ? 261 LEU C CD1 1 
ATOM 5791 C CD2 . LEU C 3 5   ? 168.743 122.366 165.594 1.00 18.30  ? 261 LEU C CD2 1 
ATOM 5792 N N   . PHE C 3 6   ? 169.598 126.741 167.152 1.00 9.59   ? 262 PHE C N   1 
ATOM 5793 C CA  . PHE C 3 6   ? 169.333 128.130 167.498 1.00 9.23   ? 262 PHE C CA  1 
ATOM 5794 C C   . PHE C 3 6   ? 167.894 128.429 167.098 1.00 8.97   ? 262 PHE C C   1 
ATOM 5795 O O   . PHE C 3 6   ? 167.532 128.317 165.915 1.00 10.29  ? 262 PHE C O   1 
ATOM 5796 C CB  . PHE C 3 6   ? 170.312 129.031 166.725 1.00 10.10  ? 262 PHE C CB  1 
ATOM 5797 C CG  . PHE C 3 6   ? 169.957 130.484 166.730 1.00 10.64  ? 262 PHE C CG  1 
ATOM 5798 C CD1 . PHE C 3 6   ? 169.628 131.130 167.902 1.00 11.74  ? 262 PHE C CD1 1 
ATOM 5799 C CD2 . PHE C 3 6   ? 169.969 131.225 165.550 1.00 11.22  ? 262 PHE C CD2 1 
ATOM 5800 C CE1 . PHE C 3 6   ? 169.310 132.470 167.903 1.00 12.64  ? 262 PHE C CE1 1 
ATOM 5801 C CE2 . PHE C 3 6   ? 169.632 132.563 165.540 1.00 12.65  ? 262 PHE C CE2 1 
ATOM 5802 C CZ  . PHE C 3 6   ? 169.307 133.183 166.716 1.00 12.85  ? 262 PHE C CZ  1 
ATOM 5803 N N   . ILE C 3 7   ? 167.082 128.796 168.086 1.00 9.26   ? 263 ILE C N   1 
ATOM 5804 C CA  . ILE C 3 7   ? 165.654 129.031 167.931 1.00 8.99   ? 263 ILE C CA  1 
ATOM 5805 C C   . ILE C 3 7   ? 165.364 130.502 168.210 1.00 9.63   ? 263 ILE C C   1 
ATOM 5806 O O   . ILE C 3 7   ? 165.833 131.045 169.213 1.00 10.42  ? 263 ILE C O   1 
ATOM 5807 C CB  . ILE C 3 7   ? 164.886 128.163 168.947 1.00 9.87   ? 263 ILE C CB  1 
ATOM 5808 C CG1 . ILE C 3 7   ? 165.144 126.676 168.706 1.00 10.89  ? 263 ILE C CG1 1 
ATOM 5809 C CG2 . ILE C 3 7   ? 163.386 128.463 168.922 1.00 11.39  ? 263 ILE C CG2 1 
ATOM 5810 C CD1 . ILE C 3 7   ? 165.057 125.866 169.969 1.00 16.09  ? 263 ILE C CD1 1 
ATOM 5811 N N   . GLY C 3 8   ? 164.563 131.132 167.349 1.00 9.89   ? 264 GLY C N   1 
ATOM 5812 C CA  . GLY C 3 8   ? 164.044 132.453 167.629 1.00 10.42  ? 264 GLY C CA  1 
ATOM 5813 C C   . GLY C 3 8   ? 162.549 132.528 167.379 1.00 9.69   ? 264 GLY C C   1 
ATOM 5814 O O   . GLY C 3 8   ? 161.969 131.706 166.675 1.00 11.04  ? 264 GLY C O   1 
ATOM 5815 N N   . GLY C 3 9   ? 161.950 133.567 167.947 1.00 10.90  ? 265 GLY C N   1 
ATOM 5816 C CA  . GLY C 3 9   ? 160.534 133.824 167.795 1.00 11.66  ? 265 GLY C CA  1 
ATOM 5817 C C   . GLY C 3 9   ? 159.647 133.266 168.883 1.00 12.10  ? 265 GLY C C   1 
ATOM 5818 O O   . GLY C 3 9   ? 158.430 133.262 168.711 1.00 13.63  ? 265 GLY C O   1 
ATOM 5819 N N   . LEU C 3 10  ? 160.205 132.773 169.985 1.00 11.06  ? 266 LEU C N   1 
ATOM 5820 C CA  . LEU C 3 10  ? 159.358 132.270 171.065 1.00 11.54  ? 266 LEU C CA  1 
ATOM 5821 C C   . LEU C 3 10  ? 158.591 133.422 171.708 1.00 12.54  ? 266 LEU C C   1 
ATOM 5822 O O   . LEU C 3 10  ? 159.158 134.496 171.931 1.00 14.10  ? 266 LEU C O   1 
ATOM 5823 C CB  . LEU C 3 10  ? 160.218 131.603 172.134 1.00 11.84  ? 266 LEU C CB  1 
ATOM 5824 C CG  . LEU C 3 10  ? 160.860 130.277 171.716 1.00 11.37  ? 266 LEU C CG  1 
ATOM 5825 C CD1 . LEU C 3 10  ? 162.117 129.985 172.522 1.00 13.14  ? 266 LEU C CD1 1 
ATOM 5826 C CD2 . LEU C 3 10  ? 159.869 129.135 171.865 1.00 12.86  ? 266 LEU C CD2 1 
ATOM 5827 N N   . PRO C 3 11  ? 157.327 133.220 172.062 1.00 13.02  ? 267 PRO C N   1 
ATOM 5828 C CA  . PRO C 3 11  ? 156.632 134.203 172.903 1.00 14.13  ? 267 PRO C CA  1 
ATOM 5829 C C   . PRO C 3 11  ? 157.452 134.505 174.147 1.00 14.17  ? 267 PRO C C   1 
ATOM 5830 O O   . PRO C 3 11  ? 157.921 133.601 174.840 1.00 14.49  ? 267 PRO C O   1 
ATOM 5831 C CB  . PRO C 3 11  ? 155.306 133.507 173.235 1.00 15.92  ? 267 PRO C CB  1 
ATOM 5832 C CG  . PRO C 3 11  ? 155.093 132.568 172.056 1.00 16.09  ? 267 PRO C CG  1 
ATOM 5833 C CD  . PRO C 3 11  ? 156.459 132.094 171.687 1.00 14.05  ? 267 PRO C CD  1 
ATOM 5834 N N   . ASN C 3 12  ? 157.603 135.795 174.454 1.00 14.99  ? 268 ASN C N   1 
ATOM 5835 C CA  . ASN C 3 12  ? 158.549 136.186 175.491 0.58 15.49  ? 268 ASN C CA  1 
ATOM 5836 C C   . ASN C 3 12  ? 158.079 135.825 176.895 1.00 15.41  ? 268 ASN C C   1 
ATOM 5837 O O   . ASN C 3 12  ? 158.900 135.799 177.811 1.00 18.99  ? 268 ASN C O   1 
ATOM 5838 C CB  . ASN C 3 12  ? 158.879 137.676 175.395 0.58 19.96  ? 268 ASN C CB  1 
ATOM 5839 C CG  . ASN C 3 12  ? 159.778 138.004 174.216 0.58 23.90  ? 268 ASN C CG  1 
ATOM 5840 O OD1 . ASN C 3 12  ? 160.535 137.158 173.742 0.58 25.35  ? 268 ASN C OD1 1 
ATOM 5841 N ND2 . ASN C 3 12  ? 159.708 139.242 173.744 0.58 25.99  ? 268 ASN C ND2 1 
ATOM 5842 N N   . TYR C 3 13  ? 156.797 135.524 177.089 1.00 14.73  ? 269 TYR C N   1 
ATOM 5843 C CA  . TYR C 3 13  ? 156.337 135.171 178.428 1.00 15.27  ? 269 TYR C CA  1 
ATOM 5844 C C   . TYR C 3 13  ? 156.574 133.709 178.785 1.00 14.83  ? 269 TYR C C   1 
ATOM 5845 O O   . TYR C 3 13  ? 156.455 133.357 179.963 1.00 15.76  ? 269 TYR C O   1 
ATOM 5846 C CB  . TYR C 3 13  ? 154.860 135.529 178.621 1.00 15.46  ? 269 TYR C CB  1 
ATOM 5847 C CG  . TYR C 3 13  ? 153.933 134.810 177.683 1.00 15.03  ? 269 TYR C CG  1 
ATOM 5848 C CD1 . TYR C 3 13  ? 153.444 133.548 177.983 1.00 16.12  ? 269 TYR C CD1 1 
ATOM 5849 C CD2 . TYR C 3 13  ? 153.549 135.399 176.495 1.00 14.96  ? 269 TYR C CD2 1 
ATOM 5850 C CE1 . TYR C 3 13  ? 152.598 132.899 177.124 1.00 17.51  ? 269 TYR C CE1 1 
ATOM 5851 C CE2 . TYR C 3 13  ? 152.709 134.760 175.630 1.00 16.08  ? 269 TYR C CE2 1 
ATOM 5852 C CZ  . TYR C 3 13  ? 152.232 133.505 175.947 1.00 17.51  ? 269 TYR C CZ  1 
ATOM 5853 O OH  . TYR C 3 13  ? 151.371 132.843 175.103 1.00 22.34  ? 269 TYR C OH  1 
ATOM 5854 N N   . LEU C 3 14  ? 156.889 132.846 177.819 1.00 14.08  ? 270 LEU C N   1 
ATOM 5855 C CA  . LEU C 3 14  ? 157.184 131.461 178.156 1.00 14.51  ? 270 LEU C CA  1 
ATOM 5856 C C   . LEU C 3 14  ? 158.466 131.393 178.974 1.00 14.15  ? 270 LEU C C   1 
ATOM 5857 O O   . LEU C 3 14  ? 159.446 132.090 178.682 1.00 15.15  ? 270 LEU C O   1 
ATOM 5858 C CB  . LEU C 3 14  ? 157.317 130.626 176.881 1.00 14.95  ? 270 LEU C CB  1 
ATOM 5859 C CG  . LEU C 3 14  ? 156.056 130.527 176.015 1.00 15.81  ? 270 LEU C CG  1 
ATOM 5860 C CD1 . LEU C 3 14  ? 156.349 129.764 174.738 1.00 17.92  ? 270 LEU C CD1 1 
ATOM 5861 C CD2 . LEU C 3 14  ? 154.914 129.863 176.764 1.00 16.18  ? 270 LEU C CD2 1 
ATOM 5862 N N   . ASN C 3 15  ? 158.464 130.532 179.994 1.00 14.81  ? 271 ASN C N   1 
ATOM 5863 C CA  . ASN C 3 15  ? 159.609 130.375 180.879 1.00 15.47  ? 271 ASN C CA  1 
ATOM 5864 C C   . ASN C 3 15  ? 160.464 129.175 180.462 1.00 14.49  ? 271 ASN C C   1 
ATOM 5865 O O   . ASN C 3 15  ? 160.158 128.467 179.500 1.00 13.71  ? 271 ASN C O   1 
ATOM 5866 C CB  . ASN C 3 15  ? 159.156 130.313 182.343 1.00 17.19  ? 271 ASN C CB  1 
ATOM 5867 C CG  . ASN C 3 15  ? 158.332 129.076 182.663 1.00 19.27  ? 271 ASN C CG  1 
ATOM 5868 O OD1 . ASN C 3 15  ? 158.552 127.996 182.122 1.00 18.40  ? 271 ASN C OD1 1 
ATOM 5869 N ND2 . ASN C 3 15  ? 157.383 129.228 183.572 1.00 22.50  ? 271 ASN C ND2 1 
ATOM 5870 N N   . ASP C 3 16  ? 161.577 128.975 181.175 1.00 15.43  ? 272 ASP C N   1 
ATOM 5871 C CA  . ASP C 3 16  ? 162.519 127.912 180.823 1.00 15.28  ? 272 ASP C CA  1 
ATOM 5872 C C   . ASP C 3 16  ? 161.845 126.552 180.796 1.00 15.09  ? 272 ASP C C   1 
ATOM 5873 O O   . ASP C 3 16  ? 162.083 125.750 179.889 1.00 14.61  ? 272 ASP C O   1 
ATOM 5874 C CB  . ASP C 3 16  ? 163.652 127.839 181.840 1.00 17.22  ? 272 ASP C CB  1 
ATOM 5875 C CG  . ASP C 3 16  ? 164.608 129.002 181.758 1.00 19.59  ? 272 ASP C CG  1 
ATOM 5876 O OD1 . ASP C 3 16  ? 164.586 129.730 180.755 1.00 19.15  ? 272 ASP C OD1 1 
ATOM 5877 O OD2 . ASP C 3 16  ? 165.370 129.209 182.724 1.00 24.51  ? 272 ASP C OD2 1 
ATOM 5878 N N   . ASP C 3 17  ? 161.054 126.247 181.819 1.00 15.88  ? 273 ASP C N   1 
ATOM 5879 C CA  . ASP C 3 17  ? 160.450 124.921 181.901 1.00 16.87  ? 273 ASP C CA  1 
ATOM 5880 C C   . ASP C 3 17  ? 159.488 124.690 180.746 1.00 14.84  ? 273 ASP C C   1 
ATOM 5881 O O   . ASP C 3 17  ? 159.416 123.586 180.196 1.00 14.54  ? 273 ASP C O   1 
ATOM 5882 C CB  . ASP C 3 17  ? 159.735 124.748 183.242 1.00 21.36  ? 273 ASP C CB  1 
ATOM 5883 C CG  . ASP C 3 17  ? 160.700 124.670 184.419 1.00 28.32  ? 273 ASP C CG  1 
ATOM 5884 O OD1 . ASP C 3 17  ? 161.823 124.147 184.243 1.00 33.03  ? 273 ASP C OD1 1 
ATOM 5885 O OD2 . ASP C 3 17  ? 160.324 125.114 185.529 1.00 34.07  ? 273 ASP C OD2 1 
ATOM 5886 N N   . GLN C 3 18  ? 158.740 125.725 180.369 1.00 13.51  ? 274 GLN C N   1 
ATOM 5887 C CA  . GLN C 3 18  ? 157.777 125.589 179.288 1.00 12.76  ? 274 GLN C CA  1 
ATOM 5888 C C   . GLN C 3 18  ? 158.469 125.415 177.947 1.00 12.61  ? 274 GLN C C   1 
ATOM 5889 O O   . GLN C 3 18  ? 158.066 124.574 177.135 1.00 11.67  ? 274 GLN C O   1 
ATOM 5890 C CB  . GLN C 3 18  ? 156.865 126.806 179.268 1.00 13.99  ? 274 GLN C CB  1 
ATOM 5891 C CG  . GLN C 3 18  ? 156.015 126.887 180.514 1.00 16.08  ? 274 GLN C CG  1 
ATOM 5892 C CD  . GLN C 3 18  ? 155.320 128.216 180.679 1.00 15.69  ? 274 GLN C CD  1 
ATOM 5893 O OE1 . GLN C 3 18  ? 155.863 129.291 180.386 1.00 16.01  ? 274 GLN C OE1 1 
ATOM 5894 N NE2 . GLN C 3 18  ? 154.108 128.161 181.176 1.00 15.51  ? 274 GLN C NE2 1 
ATOM 5895 N N   . VAL C 3 19  ? 159.520 126.187 177.687 1.00 11.94  ? 275 VAL C N   1 
ATOM 5896 C CA  . VAL C 3 19  ? 160.244 126.005 176.435 1.00 11.76  ? 275 VAL C CA  1 
ATOM 5897 C C   . VAL C 3 19  ? 160.905 124.631 176.405 1.00 11.46  ? 275 VAL C C   1 
ATOM 5898 O O   . VAL C 3 19  ? 160.853 123.924 175.399 1.00 11.66  ? 275 VAL C O   1 
ATOM 5899 C CB  . VAL C 3 19  ? 161.233 127.167 176.221 1.00 12.68  ? 275 VAL C CB  1 
ATOM 5900 C CG1 . VAL C 3 19  ? 162.052 126.943 174.970 1.00 13.08  ? 275 VAL C CG1 1 
ATOM 5901 C CG2 . VAL C 3 19  ? 160.481 128.487 176.120 1.00 13.65  ? 275 VAL C CG2 1 
ATOM 5902 N N   . LYS C 3 20  ? 161.497 124.227 177.529 0.55 12.15  ? 276 LYS C N   1 
ATOM 5903 C CA  . LYS C 3 20  ? 162.153 122.930 177.618 0.55 13.37  ? 276 LYS C CA  1 
ATOM 5904 C C   . LYS C 3 20  ? 161.172 121.795 177.358 0.55 11.36  ? 276 LYS C C   1 
ATOM 5905 O O   . LYS C 3 20  ? 161.526 120.792 176.734 0.55 10.78  ? 276 LYS C O   1 
ATOM 5906 C CB  . LYS C 3 20  ? 162.769 122.802 179.006 0.55 18.13  ? 276 LYS C CB  1 
ATOM 5907 C CG  . LYS C 3 20  ? 163.870 121.779 179.102 0.55 19.97  ? 276 LYS C CG  1 
ATOM 5908 C CD  . LYS C 3 20  ? 164.403 121.674 180.532 0.55 22.69  ? 276 LYS C CD  1 
ATOM 5909 C CE  . LYS C 3 20  ? 164.812 123.032 181.112 0.55 24.29  ? 276 LYS C CE  1 
ATOM 5910 N NZ  . LYS C 3 20  ? 165.475 122.908 182.439 0.55 24.62  ? 276 LYS C NZ  1 
ATOM 5911 N N   . GLU C 3 21  ? 159.941 121.922 177.851 1.00 11.78  ? 277 GLU C N   1 
ATOM 5912 C CA  . GLU C 3 21  ? 158.945 120.886 177.631 1.00 11.96  ? 277 GLU C CA  1 
ATOM 5913 C C   . GLU C 3 21  ? 158.630 120.735 176.152 1.00 11.53  ? 277 GLU C C   1 
ATOM 5914 O O   . GLU C 3 21  ? 158.549 119.613 175.641 1.00 12.52  ? 277 GLU C O   1 
ATOM 5915 C CB  . GLU C 3 21  ? 157.677 121.197 178.414 1.00 12.91  ? 277 GLU C CB  1 
ATOM 5916 C CG  . GLU C 3 21  ? 156.625 120.119 178.279 1.00 15.20  ? 277 GLU C CG  1 
ATOM 5917 C CD  . GLU C 3 21  ? 155.322 120.507 178.928 1.00 21.56  ? 277 GLU C CD  1 
ATOM 5918 O OE1 . GLU C 3 21  ? 155.192 120.307 180.149 1.00 25.36  ? 277 GLU C OE1 1 
ATOM 5919 O OE2 . GLU C 3 21  ? 154.426 121.042 178.229 1.00 23.28  ? 277 GLU C OE2 1 
ATOM 5920 N N   . LEU C 3 22  ? 158.468 121.855 175.441 1.00 10.99  ? 278 LEU C N   1 
ATOM 5921 C CA  . LEU C 3 22  ? 158.245 121.781 173.999 1.00 10.98  ? 278 LEU C CA  1 
ATOM 5922 C C   . LEU C 3 22  ? 159.421 121.101 173.302 1.00 10.75  ? 278 LEU C C   1 
ATOM 5923 O O   . LEU C 3 22  ? 159.239 120.228 172.448 1.00 11.85  ? 278 LEU C O   1 
ATOM 5924 C CB  . LEU C 3 22  ? 158.025 123.185 173.445 1.00 12.37  ? 278 LEU C CB  1 
ATOM 5925 C CG  . LEU C 3 22  ? 157.933 123.298 171.921 1.00 13.24  ? 278 LEU C CG  1 
ATOM 5926 C CD1 . LEU C 3 22  ? 156.741 122.518 171.364 1.00 14.82  ? 278 LEU C CD1 1 
ATOM 5927 C CD2 . LEU C 3 22  ? 157.877 124.770 171.522 1.00 14.97  ? 278 LEU C CD2 1 
ATOM 5928 N N   . LEU C 3 23  ? 160.638 121.470 173.666 1.00 10.01  ? 279 LEU C N   1 
ATOM 5929 C CA  . LEU C 3 23  ? 161.789 120.878 173.007 1.00 10.01  ? 279 LEU C CA  1 
ATOM 5930 C C   . LEU C 3 23  ? 161.935 119.396 173.331 1.00 10.09  ? 279 LEU C C   1 
ATOM 5931 O O   . LEU C 3 23  ? 162.286 118.601 172.450 1.00 10.26  ? 279 LEU C O   1 
ATOM 5932 C CB  . LEU C 3 23  ? 163.055 121.633 173.378 1.00 10.95  ? 279 LEU C CB  1 
ATOM 5933 C CG  . LEU C 3 23  ? 163.080 123.108 173.000 1.00 13.16  ? 279 LEU C CG  1 
ATOM 5934 C CD1 . LEU C 3 23  ? 164.372 123.747 173.432 1.00 14.40  ? 279 LEU C CD1 1 
ATOM 5935 C CD2 . LEU C 3 23  ? 162.881 123.289 171.521 1.00 16.23  ? 279 LEU C CD2 1 
ATOM 5936 N N   . THR C 3 24  ? 161.730 118.999 174.589 1.00 10.70  ? 280 THR C N   1 
ATOM 5937 C CA  . THR C 3 24  ? 161.928 117.595 174.945 1.00 12.04  ? 280 THR C CA  1 
ATOM 5938 C C   . THR C 3 24  ? 160.816 116.710 174.422 1.00 11.18  ? 280 THR C C   1 
ATOM 5939 O O   . THR C 3 24  ? 160.975 115.490 174.431 1.00 12.12  ? 280 THR C O   1 
ATOM 5940 C CB  . THR C 3 24  ? 162.130 117.398 176.450 1.00 14.99  ? 280 THR C CB  1 
ATOM 5941 O OG1 . THR C 3 24  ? 160.960 117.785 177.144 1.00 16.45  ? 280 THR C OG1 1 
ATOM 5942 C CG2 . THR C 3 24  ? 163.294 118.212 176.952 1.00 16.81  ? 280 THR C CG2 1 
ATOM 5943 N N   . SER C 3 25  ? 159.732 117.284 173.899 1.00 11.56  ? 281 SER C N   1 
ATOM 5944 C CA  . SER C 3 25  ? 158.743 116.452 173.231 1.00 12.36  ? 281 SER C CA  1 
ATOM 5945 C C   . SER C 3 25  ? 159.325 115.737 172.017 1.00 13.01  ? 281 SER C C   1 
ATOM 5946 O O   . SER C 3 25  ? 158.795 114.702 171.619 1.00 15.65  ? 281 SER C O   1 
ATOM 5947 C CB  . SER C 3 25  ? 157.508 117.255 172.840 1.00 13.74  ? 281 SER C CB  1 
ATOM 5948 O OG  . SER C 3 25  ? 157.745 118.081 171.713 1.00 13.75  ? 281 SER C OG  1 
ATOM 5949 N N   . PHE C 3 26  ? 160.404 116.255 171.432 1.00 10.38  ? 282 PHE C N   1 
ATOM 5950 C CA  . PHE C 3 26  ? 161.076 115.586 170.324 1.00 10.85  ? 282 PHE C CA  1 
ATOM 5951 C C   . PHE C 3 26  ? 162.028 114.492 170.780 1.00 10.62  ? 282 PHE C C   1 
ATOM 5952 O O   . PHE C 3 26  ? 162.196 113.500 170.066 1.00 12.28  ? 282 PHE C O   1 
ATOM 5953 C CB  . PHE C 3 26  ? 161.814 116.620 169.479 1.00 10.91  ? 282 PHE C CB  1 
ATOM 5954 C CG  . PHE C 3 26  ? 160.887 117.547 168.769 1.00 10.20  ? 282 PHE C CG  1 
ATOM 5955 C CD1 . PHE C 3 26  ? 160.400 117.218 167.521 1.00 11.35  ? 282 PHE C CD1 1 
ATOM 5956 C CD2 . PHE C 3 26  ? 160.458 118.721 169.350 1.00 10.87  ? 282 PHE C CD2 1 
ATOM 5957 C CE1 . PHE C 3 26  ? 159.514 118.041 166.854 1.00 12.70  ? 282 PHE C CE1 1 
ATOM 5958 C CE2 . PHE C 3 26  ? 159.558 119.556 168.697 1.00 12.45  ? 282 PHE C CE2 1 
ATOM 5959 C CZ  . PHE C 3 26  ? 159.094 119.219 167.443 1.00 12.56  ? 282 PHE C CZ  1 
ATOM 5960 N N   . GLY C 3 27  ? 162.668 114.656 171.931 1.00 10.72  ? 283 GLY C N   1 
ATOM 5961 C CA  . GLY C 3 27  ? 163.623 113.714 172.467 1.00 10.15  ? 283 GLY C CA  1 
ATOM 5962 C C   . GLY C 3 27  ? 164.505 114.405 173.481 1.00 9.74   ? 283 GLY C C   1 
ATOM 5963 O O   . GLY C 3 27  ? 164.369 115.608 173.734 1.00 10.46  ? 283 GLY C O   1 
ATOM 5964 N N   . PRO C 3 28  ? 165.427 113.651 174.088 1.00 10.22  ? 284 PRO C N   1 
ATOM 5965 C CA  . PRO C 3 28  ? 166.168 114.188 175.234 1.00 10.80  ? 284 PRO C CA  1 
ATOM 5966 C C   . PRO C 3 28  ? 167.181 115.249 174.851 1.00 9.89   ? 284 PRO C C   1 
ATOM 5967 O O   . PRO C 3 28  ? 167.840 115.165 173.811 1.00 9.79   ? 284 PRO C O   1 
ATOM 5968 C CB  . PRO C 3 28  ? 166.878 112.953 175.824 1.00 13.36  ? 284 PRO C CB  1 
ATOM 5969 C CG  . PRO C 3 28  ? 166.187 111.811 175.299 1.00 15.80  ? 284 PRO C CG  1 
ATOM 5970 C CD  . PRO C 3 28  ? 165.519 112.182 174.025 1.00 11.28  ? 284 PRO C CD  1 
ATOM 5971 N N   . LEU C 3 29  ? 167.325 116.230 175.748 1.00 11.22  ? 285 LEU C N   1 
ATOM 5972 C CA  . LEU C 3 29  ? 168.284 117.311 175.629 1.00 10.95  ? 285 LEU C CA  1 
ATOM 5973 C C   . LEU C 3 29  ? 169.520 117.045 176.464 1.00 11.85  ? 285 LEU C C   1 
ATOM 5974 O O   . LEU C 3 29  ? 169.450 116.477 177.558 1.00 14.17  ? 285 LEU C O   1 
ATOM 5975 C CB  . LEU C 3 29  ? 167.699 118.630 176.143 1.00 11.77  ? 285 LEU C CB  1 
ATOM 5976 C CG  . LEU C 3 29  ? 166.612 119.251 175.284 1.00 12.31  ? 285 LEU C CG  1 
ATOM 5977 C CD1 . LEU C 3 29  ? 165.983 120.409 176.022 1.00 14.26  ? 285 LEU C CD1 1 
ATOM 5978 C CD2 . LEU C 3 29  ? 167.171 119.717 173.969 1.00 13.34  ? 285 LEU C CD2 1 
ATOM 5979 N N   . LYS C 3 30  ? 170.645 117.505 175.929 0.49 12.89  ? 286 LYS C N   1 
ATOM 5980 C CA  . LYS C 3 30  ? 171.911 117.557 176.631 0.49 13.16  ? 286 LYS C CA  1 
ATOM 5981 C C   . LYS C 3 30  ? 172.223 118.945 177.171 0.49 13.94  ? 286 LYS C C   1 
ATOM 5982 O O   . LYS C 3 30  ? 172.885 119.056 178.206 0.49 15.67  ? 286 LYS C O   1 
ATOM 5983 C CB  . LYS C 3 30  ? 173.025 117.087 175.688 0.49 16.56  ? 286 LYS C CB  1 
ATOM 5984 C CG  . LYS C 3 30  ? 174.331 116.818 176.385 0.49 18.45  ? 286 LYS C CG  1 
ATOM 5985 C CD  . LYS C 3 30  ? 175.161 115.789 175.654 0.49 19.39  ? 286 LYS C CD  1 
ATOM 5986 C CE  . LYS C 3 30  ? 176.401 115.438 176.454 0.49 18.31  ? 286 LYS C CE  1 
ATOM 5987 N NZ  . LYS C 3 30  ? 177.183 114.354 175.810 0.49 17.32  ? 286 LYS C NZ  1 
ATOM 5988 N N   . ALA C 3 31  ? 171.712 119.998 176.534 1.00 12.91  ? 287 ALA C N   1 
ATOM 5989 C CA  . ALA C 3 31  ? 171.986 121.373 176.937 1.00 13.28  ? 287 ALA C CA  1 
ATOM 5990 C C   . ALA C 3 31  ? 170.814 122.241 176.517 1.00 11.63  ? 287 ALA C C   1 
ATOM 5991 O O   . ALA C 3 31  ? 170.126 121.928 175.544 1.00 10.91  ? 287 ALA C O   1 
ATOM 5992 C CB  . ALA C 3 31  ? 173.262 121.903 176.285 1.00 15.71  ? 287 ALA C CB  1 
ATOM 5993 N N   . PHE C 3 32  ? 170.612 123.332 177.244 1.00 11.75  ? 288 PHE C N   1 
ATOM 5994 C CA  . PHE C 3 32  ? 169.514 124.239 176.957 1.00 11.96  ? 288 PHE C CA  1 
ATOM 5995 C C   . PHE C 3 32  ? 169.737 125.570 177.660 1.00 11.04  ? 288 PHE C C   1 
ATOM 5996 O O   . PHE C 3 32  ? 170.130 125.590 178.826 1.00 12.91  ? 288 PHE C O   1 
ATOM 5997 C CB  . PHE C 3 32  ? 168.209 123.661 177.507 1.00 12.87  ? 288 PHE C CB  1 
ATOM 5998 C CG  . PHE C 3 32  ? 167.081 124.635 177.445 1.00 12.58  ? 288 PHE C CG  1 
ATOM 5999 C CD1 . PHE C 3 32  ? 166.426 124.845 176.257 1.00 12.85  ? 288 PHE C CD1 1 
ATOM 6000 C CD2 . PHE C 3 32  ? 166.723 125.410 178.540 1.00 14.92  ? 288 PHE C CD2 1 
ATOM 6001 C CE1 . PHE C 3 32  ? 165.408 125.775 176.164 1.00 13.97  ? 288 PHE C CE1 1 
ATOM 6002 C CE2 . PHE C 3 32  ? 165.705 126.339 178.449 1.00 17.43  ? 288 PHE C CE2 1 
ATOM 6003 C CZ  . PHE C 3 32  ? 165.052 126.525 177.262 1.00 15.95  ? 288 PHE C CZ  1 
ATOM 6004 N N   . ASN C 3 33  ? 169.416 126.670 176.981 1.00 10.81  ? 289 ASN C N   1 
ATOM 6005 C CA  . ASN C 3 33  ? 169.223 127.941 177.670 1.00 10.99  ? 289 ASN C CA  1 
ATOM 6006 C C   . ASN C 3 33  ? 168.237 128.812 176.909 1.00 10.30  ? 289 ASN C C   1 
ATOM 6007 O O   . ASN C 3 33  ? 168.157 128.783 175.679 1.00 10.94  ? 289 ASN C O   1 
ATOM 6008 C CB  . ASN C 3 33  ? 170.532 128.681 177.971 1.00 12.59  ? 289 ASN C CB  1 
ATOM 6009 C CG  . ASN C 3 33  ? 171.016 129.539 176.817 1.00 13.20  ? 289 ASN C CG  1 
ATOM 6010 O OD1 . ASN C 3 33  ? 171.563 129.015 175.837 1.00 14.05  ? 289 ASN C OD1 1 
ATOM 6011 N ND2 . ASN C 3 33  ? 170.854 130.854 176.937 1.00 14.35  ? 289 ASN C ND2 1 
ATOM 6012 N N   . LEU C 3 34  ? 167.483 129.588 177.675 1.00 10.90  ? 290 LEU C N   1 
ATOM 6013 C CA  . LEU C 3 34  ? 166.538 130.561 177.162 1.00 10.79  ? 290 LEU C CA  1 
ATOM 6014 C C   . LEU C 3 34  ? 167.167 131.940 177.381 1.00 10.62  ? 290 LEU C C   1 
ATOM 6015 O O   . LEU C 3 34  ? 167.463 132.315 178.521 1.00 11.95  ? 290 LEU C O   1 
ATOM 6016 C CB  . LEU C 3 34  ? 165.209 130.438 177.915 1.00 11.48  ? 290 LEU C CB  1 
ATOM 6017 C CG  . LEU C 3 34  ? 164.094 131.389 177.495 1.00 12.14  ? 290 LEU C CG  1 
ATOM 6018 C CD1 . LEU C 3 34  ? 163.687 131.208 176.031 1.00 12.45  ? 290 LEU C CD1 1 
ATOM 6019 C CD2 . LEU C 3 34  ? 162.886 131.235 178.414 1.00 14.15  ? 290 LEU C CD2 1 
ATOM 6020 N N   . VAL C 3 35  ? 167.370 132.681 176.296 1.00 10.69  ? 291 VAL C N   1 
ATOM 6021 C CA  . VAL C 3 35  ? 168.106 133.946 176.345 1.00 10.90  ? 291 VAL C CA  1 
ATOM 6022 C C   . VAL C 3 35  ? 167.287 135.002 177.070 1.00 11.06  ? 291 VAL C C   1 
ATOM 6023 O O   . VAL C 3 35  ? 166.115 135.222 176.749 1.00 11.90  ? 291 VAL C O   1 
ATOM 6024 C CB  . VAL C 3 35  ? 168.447 134.405 174.918 1.00 12.01  ? 291 VAL C CB  1 
ATOM 6025 C CG1 . VAL C 3 35  ? 169.175 135.724 174.938 1.00 13.35  ? 291 VAL C CG1 1 
ATOM 6026 C CG2 . VAL C 3 35  ? 169.299 133.361 174.204 1.00 12.35  ? 291 VAL C CG2 1 
ATOM 6027 N N   . LYS C 3 36  ? 167.915 135.691 178.024 1.00 11.81  ? 292 LYS C N   1 
ATOM 6028 C CA  . LYS C 3 36  ? 167.251 136.717 178.809 1.00 13.14  ? 292 LYS C CA  1 
ATOM 6029 C C   . LYS C 3 36  ? 168.071 137.993 178.814 1.00 11.95  ? 292 LYS C C   1 
ATOM 6030 O O   . LYS C 3 36  ? 169.298 137.968 178.739 1.00 12.90  ? 292 LYS C O   1 
ATOM 6031 C CB  . LYS C 3 36  ? 167.087 136.247 180.237 1.00 16.42  ? 292 LYS C CB  1 
ATOM 6032 C CG  . LYS C 3 36  ? 166.164 135.035 180.329 1.00 21.02  ? 292 LYS C CG  1 
ATOM 6033 C CD  . LYS C 3 36  ? 166.035 134.480 181.712 1.00 23.56  ? 292 LYS C CD  1 
ATOM 6034 C CE  . LYS C 3 36  ? 165.282 133.168 181.684 1.00 23.37  ? 292 LYS C CE  1 
ATOM 6035 N NZ  . LYS C 3 36  ? 166.144 132.072 181.183 1.00 21.66  ? 292 LYS C NZ  1 
ATOM 6036 N N   . ASP C 3 37  ? 167.371 139.115 178.927 1.00 11.69  ? 293 ASP C N   1 
ATOM 6037 C CA  . ASP C 3 37  ? 168.012 140.391 179.204 1.00 10.71  ? 293 ASP C CA  1 
ATOM 6038 C C   . ASP C 3 37  ? 168.635 140.335 180.590 1.00 10.50  ? 293 ASP C C   1 
ATOM 6039 O O   . ASP C 3 37  ? 167.966 139.989 181.565 1.00 12.08  ? 293 ASP C O   1 
ATOM 6040 C CB  . ASP C 3 37  ? 166.932 141.474 179.135 1.00 12.40  ? 293 ASP C CB  1 
ATOM 6041 C CG  . ASP C 3 37  ? 167.458 142.877 179.336 1.00 12.26  ? 293 ASP C CG  1 
ATOM 6042 O OD1 . ASP C 3 37  ? 167.940 143.218 180.428 1.00 11.67  ? 293 ASP C OD1 1 
ATOM 6043 O OD2 . ASP C 3 37  ? 167.365 143.680 178.382 1.00 15.29  ? 293 ASP C OD2 1 
ATOM 6044 N N   . SER C 3 38  ? 169.915 140.681 180.689 1.00 9.62   ? 294 SER C N   1 
ATOM 6045 C CA  . SER C 3 38  ? 170.606 140.551 181.968 1.00 10.95  ? 294 SER C CA  1 
ATOM 6046 C C   . SER C 3 38  ? 170.105 141.517 183.026 1.00 11.66  ? 294 SER C C   1 
ATOM 6047 O O   . SER C 3 38  ? 170.263 141.243 184.215 1.00 14.99  ? 294 SER C O   1 
ATOM 6048 C CB  . SER C 3 38  ? 172.096 140.778 181.786 1.00 11.84  ? 294 SER C CB  1 
ATOM 6049 O OG  . SER C 3 38  ? 172.641 139.742 181.003 1.00 12.94  ? 294 SER C OG  1 
ATOM 6050 N N   . ALA C 3 39  ? 169.537 142.650 182.638 1.00 10.61  ? 295 ALA C N   1 
ATOM 6051 C CA  . ALA C 3 39  ? 169.098 143.677 183.580 1.00 11.56  ? 295 ALA C CA  1 
ATOM 6052 C C   . ALA C 3 39  ? 167.641 143.509 183.978 1.00 13.23  ? 295 ALA C C   1 
ATOM 6053 O O   . ALA C 3 39  ? 167.302 143.736 185.138 1.00 17.23  ? 295 ALA C O   1 
ATOM 6054 C CB  . ALA C 3 39  ? 169.333 145.054 182.968 1.00 12.11  ? 295 ALA C CB  1 
ATOM 6055 N N   . THR C 3 40  ? 166.768 143.127 183.051 1.00 12.91  ? 296 THR C N   1 
ATOM 6056 C CA  . THR C 3 40  ? 165.353 142.990 183.351 1.00 13.61  ? 296 THR C CA  1 
ATOM 6057 C C   . THR C 3 40  ? 164.946 141.560 183.628 1.00 14.18  ? 296 THR C C   1 
ATOM 6058 O O   . THR C 3 40  ? 163.867 141.338 184.186 1.00 15.90  ? 296 THR C O   1 
ATOM 6059 C CB  . THR C 3 40  ? 164.492 143.496 182.200 1.00 14.36  ? 296 THR C CB  1 
ATOM 6060 O OG1 . THR C 3 40  ? 164.631 142.573 181.114 1.00 14.10  ? 296 THR C OG1 1 
ATOM 6061 C CG2 . THR C 3 40  ? 164.895 144.898 181.773 1.00 16.94  ? 296 THR C CG2 1 
ATOM 6062 N N   . GLY C 3 41  ? 165.770 140.598 183.234 1.00 14.61  ? 297 GLY C N   1 
ATOM 6063 C CA  . GLY C 3 41  ? 165.451 139.198 183.378 1.00 17.22  ? 297 GLY C CA  1 
ATOM 6064 C C   . GLY C 3 41  ? 164.446 138.677 182.382 1.00 17.99  ? 297 GLY C C   1 
ATOM 6065 O O   . GLY C 3 41  ? 164.140 137.483 182.410 1.00 21.64  ? 297 GLY C O   1 
ATOM 6066 N N   . LEU C 3 42  ? 163.945 139.505 181.477 1.00 16.72  ? 298 LEU C N   1 
ATOM 6067 C CA  . LEU C 3 42  ? 162.893 139.062 180.579 1.00 17.45  ? 298 LEU C CA  1 
ATOM 6068 C C   . LEU C 3 42  ? 163.469 138.296 179.398 1.00 15.94  ? 298 LEU C C   1 
ATOM 6069 O O   . LEU C 3 42  ? 164.571 138.569 178.926 1.00 16.34  ? 298 LEU C O   1 
ATOM 6070 C CB  . LEU C 3 42  ? 162.088 140.256 180.079 1.00 20.49  ? 298 LEU C CB  1 
ATOM 6071 C CG  . LEU C 3 42  ? 161.436 141.072 181.194 1.00 23.93  ? 298 LEU C CG  1 
ATOM 6072 C CD1 . LEU C 3 42  ? 160.682 142.224 180.577 1.00 26.47  ? 298 LEU C CD1 1 
ATOM 6073 C CD2 . LEU C 3 42  ? 160.510 140.218 182.056 1.00 26.09  ? 298 LEU C CD2 1 
ATOM 6074 N N   . SER C 3 43  ? 162.707 137.310 178.937 1.00 15.41  ? 299 SER C N   1 
ATOM 6075 C CA  . SER C 3 43  ? 163.111 136.508 177.799 1.00 13.61  ? 299 SER C CA  1 
ATOM 6076 C C   . SER C 3 43  ? 163.150 137.336 176.520 1.00 13.36  ? 299 SER C C   1 
ATOM 6077 O O   . SER C 3 43  ? 162.267 138.162 176.263 1.00 15.61  ? 299 SER C O   1 
ATOM 6078 C CB  . SER C 3 43  ? 162.114 135.374 177.608 1.00 15.22  ? 299 SER C CB  1 
ATOM 6079 O OG  . SER C 3 43  ? 162.382 134.717 176.387 1.00 14.31  ? 299 SER C OG  1 
ATOM 6080 N N   . LYS C 3 44  ? 164.175 137.090 175.706 1.00 12.01  ? 300 LYS C N   1 
ATOM 6081 C CA  . LYS C 3 44  ? 164.295 137.653 174.366 0.45 12.38  ? 300 LYS C CA  1 
ATOM 6082 C C   . LYS C 3 44  ? 163.677 136.761 173.296 1.00 12.95  ? 300 LYS C C   1 
ATOM 6083 O O   . LYS C 3 44  ? 163.705 137.120 172.115 1.00 14.60  ? 300 LYS C O   1 
ATOM 6084 C CB  . LYS C 3 44  ? 165.771 137.880 174.014 0.45 11.92  ? 300 LYS C CB  1 
ATOM 6085 C CG  . LYS C 3 44  ? 166.566 138.709 175.016 0.45 12.06  ? 300 LYS C CG  1 
ATOM 6086 C CD  . LYS C 3 44  ? 166.077 140.152 175.114 0.45 11.43  ? 300 LYS C CD  1 
ATOM 6087 C CE  . LYS C 3 44  ? 166.356 140.949 173.847 0.45 10.98  ? 300 LYS C CE  1 
ATOM 6088 N NZ  . LYS C 3 44  ? 165.700 142.291 173.837 0.45 11.71  ? 300 LYS C NZ  1 
ATOM 6089 N N   . GLY C 3 45  ? 163.129 135.613 173.674 1.00 12.91  ? 301 GLY C N   1 
ATOM 6090 C CA  . GLY C 3 45  ? 162.473 134.745 172.712 1.00 12.75  ? 301 GLY C CA  1 
ATOM 6091 C C   . GLY C 3 45  ? 163.410 133.897 171.890 1.00 11.94  ? 301 GLY C C   1 
ATOM 6092 O O   . GLY C 3 45  ? 162.967 133.232 170.942 1.00 12.35  ? 301 GLY C O   1 
ATOM 6093 N N   . TYR C 3 46  ? 164.683 133.885 172.239 1.00 10.79  ? 302 TYR C N   1 
ATOM 6094 C CA  . TYR C 3 46  ? 165.660 133.018 171.612 1.00 10.56  ? 302 TYR C CA  1 
ATOM 6095 C C   . TYR C 3 46  ? 166.033 131.908 172.580 1.00 10.39  ? 302 TYR C C   1 
ATOM 6096 O O   . TYR C 3 46  ? 166.088 132.112 173.795 1.00 11.58  ? 302 TYR C O   1 
ATOM 6097 C CB  . TYR C 3 46  ? 166.938 133.774 171.244 1.00 11.35  ? 302 TYR C CB  1 
ATOM 6098 C CG  . TYR C 3 46  ? 166.772 134.933 170.268 1.00 11.43  ? 302 TYR C CG  1 
ATOM 6099 C CD1 . TYR C 3 46  ? 166.628 134.708 168.908 1.00 12.23  ? 302 TYR C CD1 1 
ATOM 6100 C CD2 . TYR C 3 46  ? 166.821 136.244 170.701 1.00 13.38  ? 302 TYR C CD2 1 
ATOM 6101 C CE1 . TYR C 3 46  ? 166.499 135.751 168.013 1.00 13.54  ? 302 TYR C CE1 1 
ATOM 6102 C CE2 . TYR C 3 46  ? 166.690 137.291 169.819 1.00 13.94  ? 302 TYR C CE2 1 
ATOM 6103 C CZ  . TYR C 3 46  ? 166.539 137.042 168.472 1.00 14.07  ? 302 TYR C CZ  1 
ATOM 6104 O OH  . TYR C 3 46  ? 166.428 138.089 167.584 1.00 17.08  ? 302 TYR C OH  1 
ATOM 6105 N N   . ALA C 3 47  ? 166.307 130.730 172.037 1.00 10.15  ? 303 ALA C N   1 
ATOM 6106 C CA  . ALA C 3 47  ? 166.789 129.617 172.838 1.00 10.57  ? 303 ALA C CA  1 
ATOM 6107 C C   . ALA C 3 47  ? 167.865 128.884 172.058 1.00 9.84   ? 303 ALA C C   1 
ATOM 6108 O O   . ALA C 3 47  ? 167.858 128.849 170.822 1.00 11.13  ? 303 ALA C O   1 
ATOM 6109 C CB  . ALA C 3 47  ? 165.655 128.659 173.212 1.00 11.44  ? 303 ALA C CB  1 
ATOM 6110 N N   . PHE C 3 48  ? 168.795 128.310 172.796 1.00 10.10  ? 304 PHE C N   1 
ATOM 6111 C CA  . PHE C 3 48  ? 169.816 127.436 172.250 1.00 9.87   ? 304 PHE C CA  1 
ATOM 6112 C C   . PHE C 3 48  ? 169.677 126.084 172.923 1.00 10.74  ? 304 PHE C C   1 
ATOM 6113 O O   . PHE C 3 48  ? 169.436 126.005 174.130 1.00 12.46  ? 304 PHE C O   1 
ATOM 6114 C CB  . PHE C 3 48  ? 171.200 128.021 172.533 1.00 11.11  ? 304 PHE C CB  1 
ATOM 6115 C CG  . PHE C 3 48  ? 171.473 129.303 171.799 1.00 10.54  ? 304 PHE C CG  1 
ATOM 6116 C CD1 . PHE C 3 48  ? 170.966 130.513 172.253 1.00 11.80  ? 304 PHE C CD1 1 
ATOM 6117 C CD2 . PHE C 3 48  ? 172.217 129.298 170.634 1.00 12.37  ? 304 PHE C CD2 1 
ATOM 6118 C CE1 . PHE C 3 48  ? 171.214 131.682 171.560 1.00 12.61  ? 304 PHE C CE1 1 
ATOM 6119 C CE2 . PHE C 3 48  ? 172.476 130.461 169.946 1.00 13.86  ? 304 PHE C CE2 1 
ATOM 6120 C CZ  . PHE C 3 48  ? 171.971 131.662 170.411 1.00 13.77  ? 304 PHE C CZ  1 
ATOM 6121 N N   . CYS C 3 49  ? 169.814 125.006 172.155 1.00 10.30  ? 305 CYS C N   1 
ATOM 6122 C CA  . CYS C 3 49  ? 169.720 123.697 172.779 1.00 10.70  ? 305 CYS C CA  1 
ATOM 6123 C C   . CYS C 3 49  ? 170.575 122.694 172.025 1.00 10.48  ? 305 CYS C C   1 
ATOM 6124 O O   . CYS C 3 49  ? 171.019 122.937 170.902 1.00 11.49  ? 305 CYS C O   1 
ATOM 6125 C CB  . CYS C 3 49  ? 168.272 123.211 172.883 1.00 11.97  ? 305 CYS C CB  1 
ATOM 6126 S SG  . CYS C 3 49  ? 167.507 122.774 171.328 1.00 13.47  ? 305 CYS C SG  1 
ATOM 6127 N N   . GLU C 3 50  ? 170.819 121.570 172.684 1.00 10.11  ? 306 GLU C N   1 
ATOM 6128 C CA  . GLU C 3 50  ? 171.579 120.467 172.113 1.00 10.26  ? 306 GLU C CA  1 
ATOM 6129 C C   . GLU C 3 50  ? 170.849 119.181 172.446 1.00 9.83   ? 306 GLU C C   1 
ATOM 6130 O O   . GLU C 3 50  ? 170.605 118.907 173.622 1.00 11.22  ? 306 GLU C O   1 
ATOM 6131 C CB  . GLU C 3 50  ? 172.994 120.425 172.692 1.00 12.62  ? 306 GLU C CB  1 
ATOM 6132 C CG  . GLU C 3 50  ? 173.862 119.366 172.043 1.00 14.90  ? 306 GLU C CG  1 
ATOM 6133 C CD  . GLU C 3 50  ? 175.258 119.269 172.617 1.00 22.04  ? 306 GLU C CD  1 
ATOM 6134 O OE1 . GLU C 3 50  ? 175.572 119.988 173.591 1.00 24.81  ? 306 GLU C OE1 1 
ATOM 6135 O OE2 . GLU C 3 50  ? 176.050 118.465 172.078 1.00 27.33  ? 306 GLU C OE2 1 
ATOM 6136 N N   . TYR C 3 51  ? 170.474 118.423 171.418 1.00 9.05   ? 307 TYR C N   1 
ATOM 6137 C CA  . TYR C 3 51  ? 169.851 117.128 171.634 1.00 8.62   ? 307 TYR C CA  1 
ATOM 6138 C C   . TYR C 3 51  ? 170.911 116.047 171.783 1.00 8.97   ? 307 TYR C C   1 
ATOM 6139 O O   . TYR C 3 51  ? 171.998 116.111 171.202 1.00 10.44  ? 307 TYR C O   1 
ATOM 6140 C CB  . TYR C 3 51  ? 168.911 116.787 170.481 1.00 8.96   ? 307 TYR C CB  1 
ATOM 6141 C CG  . TYR C 3 51  ? 167.612 117.577 170.516 1.00 8.67   ? 307 TYR C CG  1 
ATOM 6142 C CD1 . TYR C 3 51  ? 166.572 117.187 171.332 1.00 9.24   ? 307 TYR C CD1 1 
ATOM 6143 C CD2 . TYR C 3 51  ? 167.441 118.723 169.756 1.00 8.79   ? 307 TYR C CD2 1 
ATOM 6144 C CE1 . TYR C 3 51  ? 165.378 117.875 171.371 1.00 9.02   ? 307 TYR C CE1 1 
ATOM 6145 C CE2 . TYR C 3 51  ? 166.234 119.434 169.787 1.00 8.70   ? 307 TYR C CE2 1 
ATOM 6146 C CZ  . TYR C 3 51  ? 165.218 119.012 170.598 1.00 8.41   ? 307 TYR C CZ  1 
ATOM 6147 O OH  . TYR C 3 51  ? 164.049 119.729 170.587 1.00 9.40   ? 307 TYR C OH  1 
ATOM 6148 N N   . VAL C 3 52  ? 170.558 115.017 172.552 1.00 8.73   ? 308 VAL C N   1 
ATOM 6149 C CA  . VAL C 3 52  ? 171.425 113.856 172.691 1.00 9.16   ? 308 VAL C CA  1 
ATOM 6150 C C   . VAL C 3 52  ? 171.630 113.160 171.344 1.00 9.38   ? 308 VAL C C   1 
ATOM 6151 O O   . VAL C 3 52  ? 172.744 112.727 171.018 1.00 11.08  ? 308 VAL C O   1 
ATOM 6152 C CB  . VAL C 3 52  ? 170.846 112.902 173.754 1.00 9.79   ? 308 VAL C CB  1 
ATOM 6153 C CG1 . VAL C 3 52  ? 171.621 111.598 173.796 1.00 11.44  ? 308 VAL C CG1 1 
ATOM 6154 C CG2 . VAL C 3 52  ? 170.872 113.560 175.145 1.00 11.51  ? 308 VAL C CG2 1 
ATOM 6155 N N   . ASP C 3 53  ? 170.559 113.012 170.565 1.00 9.57   ? 309 ASP C N   1 
ATOM 6156 C CA  . ASP C 3 53  ? 170.518 112.143 169.391 1.00 10.48  ? 309 ASP C CA  1 
ATOM 6157 C C   . ASP C 3 53  ? 170.435 112.974 168.110 1.00 9.35   ? 309 ASP C C   1 
ATOM 6158 O O   . ASP C 3 53  ? 169.611 113.897 168.011 1.00 9.82   ? 309 ASP C O   1 
ATOM 6159 C CB  . ASP C 3 53  ? 169.257 111.263 169.459 1.00 11.78  ? 309 ASP C CB  1 
ATOM 6160 C CG  . ASP C 3 53  ? 169.192 110.394 170.720 1.00 13.98  ? 309 ASP C CG  1 
ATOM 6161 O OD1 . ASP C 3 53  ? 169.985 109.441 170.776 1.00 15.62  ? 309 ASP C OD1 1 
ATOM 6162 O OD2 . ASP C 3 53  ? 168.361 110.650 171.663 1.00 13.86  ? 309 ASP C OD2 1 
ATOM 6163 N N   . ILE C 3 54  ? 171.242 112.626 167.112 1.00 10.90  ? 310 ILE C N   1 
ATOM 6164 C CA  . ILE C 3 54  ? 171.226 113.361 165.849 1.00 11.45  ? 310 ILE C CA  1 
ATOM 6165 C C   . ILE C 3 54  ? 169.883 113.242 165.130 1.00 11.16  ? 310 ILE C C   1 
ATOM 6166 O O   . ILE C 3 54  ? 169.409 114.209 164.534 1.00 10.99  ? 310 ILE C O   1 
ATOM 6167 C CB  . ILE C 3 54  ? 172.400 112.942 164.946 1.00 14.29  ? 310 ILE C CB  1 
ATOM 6168 C CG1 . ILE C 3 54  ? 172.466 113.843 163.716 1.00 16.60  ? 310 ILE C CG1 1 
ATOM 6169 C CG2 . ILE C 3 54  ? 172.290 111.482 164.532 1.00 15.66  ? 310 ILE C CG2 1 
ATOM 6170 C CD1 . ILE C 3 54  ? 172.745 115.282 164.033 1.00 19.40  ? 310 ILE C CD1 1 
ATOM 6171 N N   . ASN C 3 55  ? 169.259 112.065 165.167 0.57 10.85  ? 311 ASN C N   1 
ATOM 6172 C CA  . ASN C 3 55  ? 167.991 111.910 164.468 0.57 10.93  ? 311 ASN C CA  1 
ATOM 6173 C C   . ASN C 3 55  ? 166.940 112.812 165.081 0.57 10.68  ? 311 ASN C C   1 
ATOM 6174 O O   . ASN C 3 55  ? 166.139 113.417 164.361 0.57 11.44  ? 311 ASN C O   1 
ATOM 6175 C CB  . ASN C 3 55  ? 167.519 110.456 164.504 0.57 13.73  ? 311 ASN C CB  1 
ATOM 6176 C CG  . ASN C 3 55  ? 168.360 109.544 163.644 0.57 14.70  ? 311 ASN C CG  1 
ATOM 6177 O OD1 . ASN C 3 55  ? 169.088 109.998 162.763 0.57 16.10  ? 311 ASN C OD1 1 
ATOM 6178 N ND2 . ASN C 3 55  ? 168.256 108.242 163.890 0.57 19.02  ? 311 ASN C ND2 1 
ATOM 6179 N N   . VAL C 3 56  ? 166.949 112.935 166.414 1.00 10.12  ? 312 VAL C N   1 
ATOM 6180 C CA  . VAL C 3 56  ? 166.032 113.837 167.094 1.00 9.63   ? 312 VAL C CA  1 
ATOM 6181 C C   . VAL C 3 56  ? 166.304 115.276 166.677 1.00 9.60   ? 312 VAL C C   1 
ATOM 6182 O O   . VAL C 3 56  ? 165.373 116.044 166.420 1.00 9.78   ? 312 VAL C O   1 
ATOM 6183 C CB  . VAL C 3 56  ? 166.138 113.649 168.620 1.00 9.83   ? 312 VAL C CB  1 
ATOM 6184 C CG1 . VAL C 3 56  ? 165.340 114.704 169.330 1.00 10.75  ? 312 VAL C CG1 1 
ATOM 6185 C CG2 . VAL C 3 56  ? 165.654 112.271 169.024 1.00 11.39  ? 312 VAL C CG2 1 
ATOM 6186 N N   . THR C 3 57  ? 167.576 115.672 166.621 1.00 9.31   ? 313 THR C N   1 
ATOM 6187 C CA  . THR C 3 57  ? 167.905 117.025 166.181 1.00 9.01   ? 313 THR C CA  1 
ATOM 6188 C C   . THR C 3 57  ? 167.276 117.318 164.828 1.00 8.66   ? 313 THR C C   1 
ATOM 6189 O O   . THR C 3 57  ? 166.673 118.383 164.615 1.00 9.19   ? 313 THR C O   1 
ATOM 6190 C CB  . THR C 3 57  ? 169.424 117.228 166.102 1.00 9.93   ? 313 THR C CB  1 
ATOM 6191 O OG1 . THR C 3 57  ? 170.046 116.903 167.345 1.00 10.87  ? 313 THR C OG1 1 
ATOM 6192 C CG2 . THR C 3 57  ? 169.765 118.647 165.753 1.00 11.15  ? 313 THR C CG2 1 
ATOM 6193 N N   . ASP C 3 58  ? 167.422 116.380 163.891 1.00 9.03   ? 314 ASP C N   1 
ATOM 6194 C CA  . ASP C 3 58  ? 166.904 116.581 162.544 1.00 9.48   ? 314 ASP C CA  1 
ATOM 6195 C C   . ASP C 3 58  ? 165.382 116.730 162.550 1.00 8.73   ? 314 ASP C C   1 
ATOM 6196 O O   . ASP C 3 58  ? 164.820 117.576 161.833 1.00 9.69   ? 314 ASP C O   1 
ATOM 6197 C CB  . ASP C 3 58  ? 167.303 115.399 161.664 1.00 10.86  ? 314 ASP C CB  1 
ATOM 6198 C CG  . ASP C 3 58  ? 168.811 115.309 161.415 1.00 13.50  ? 314 ASP C CG  1 
ATOM 6199 O OD1 . ASP C 3 58  ? 169.488 116.352 161.463 1.00 15.94  ? 314 ASP C OD1 1 
ATOM 6200 O OD2 . ASP C 3 58  ? 169.316 114.194 161.131 1.00 17.76  ? 314 ASP C OD2 1 
ATOM 6201 N N   . GLN C 3 59  ? 164.698 115.917 163.351 1.00 8.61   ? 315 GLN C N   1 
ATOM 6202 C CA  . GLN C 3 59  ? 163.243 115.986 163.437 0.73 9.49   ? 315 GLN C CA  1 
ATOM 6203 C C   . GLN C 3 59  ? 162.779 117.235 164.172 1.00 8.57   ? 315 GLN C C   1 
ATOM 6204 O O   . GLN C 3 59  ? 161.711 117.780 163.846 1.00 9.37   ? 315 GLN C O   1 
ATOM 6205 C CB  . GLN C 3 59  ? 162.727 114.715 164.106 0.73 12.38  ? 315 GLN C CB  1 
ATOM 6206 C CG  . GLN C 3 59  ? 162.931 113.488 163.248 0.73 16.54  ? 315 GLN C CG  1 
ATOM 6207 C CD  . GLN C 3 59  ? 162.861 112.196 164.039 0.73 22.13  ? 315 GLN C CD  1 
ATOM 6208 O OE1 . GLN C 3 59  ? 162.225 112.135 165.097 0.73 25.80  ? 315 GLN C OE1 1 
ATOM 6209 N NE2 . GLN C 3 59  ? 163.521 111.159 163.537 0.73 22.80  ? 315 GLN C NE2 1 
ATOM 6210 N N   . ALA C 3 60  ? 163.562 117.708 165.141 1.00 8.34   ? 316 ALA C N   1 
ATOM 6211 C CA  . ALA C 3 60  ? 163.205 118.892 165.904 1.00 8.48   ? 316 ALA C CA  1 
ATOM 6212 C C   . ALA C 3 60  ? 163.321 120.144 165.054 1.00 8.29   ? 316 ALA C C   1 
ATOM 6213 O O   . ALA C 3 60  ? 162.432 120.998 165.085 1.00 9.52   ? 316 ALA C O   1 
ATOM 6214 C CB  . ALA C 3 60  ? 164.069 118.984 167.161 1.00 9.30   ? 316 ALA C CB  1 
ATOM 6215 N N   . ILE C 3 61  ? 164.420 120.298 164.316 0.48 8.64   ? 317 ILE C N   1 
ATOM 6216 C CA  . ILE C 3 61  ? 164.506 121.407 163.368 0.48 10.21  ? 317 ILE C CA  1 
ATOM 6217 C C   . ILE C 3 61  ? 163.288 121.401 162.465 0.48 9.20   ? 317 ILE C C   1 
ATOM 6218 O O   . ILE C 3 61  ? 162.593 122.413 162.304 0.48 9.78   ? 317 ILE C O   1 
ATOM 6219 C CB  . ILE C 3 61  ? 165.787 121.302 162.527 0.48 12.96  ? 317 ILE C CB  1 
ATOM 6220 C CG1 . ILE C 3 61  ? 167.002 121.449 163.400 0.48 16.54  ? 317 ILE C CG1 1 
ATOM 6221 C CG2 . ILE C 3 61  ? 165.833 122.387 161.466 0.48 15.14  ? 317 ILE C CG2 1 
ATOM 6222 C CD1 . ILE C 3 61  ? 168.219 120.845 162.783 0.48 18.91  ? 317 ILE C CD1 1 
ATOM 6223 N N   . ALA C 3 62  ? 163.036 120.263 161.830 1.00 9.61   ? 318 ALA C N   1 
ATOM 6224 C CA  . ALA C 3 62  ? 161.960 120.188 160.852 1.00 10.14  ? 318 ALA C CA  1 
ATOM 6225 C C   . ALA C 3 62  ? 160.606 120.497 161.480 1.00 9.98   ? 318 ALA C C   1 
ATOM 6226 O O   . ALA C 3 62  ? 159.731 121.107 160.843 1.00 11.37  ? 318 ALA C O   1 
ATOM 6227 C CB  . ALA C 3 62  ? 161.961 118.809 160.206 1.00 11.20  ? 318 ALA C CB  1 
ATOM 6228 N N   . GLY C 3 63  ? 160.392 120.046 162.697 1.00 9.47   ? 319 GLY C N   1 
ATOM 6229 C CA  . GLY C 3 63  ? 159.111 120.234 163.331 1.00 9.89   ? 319 GLY C CA  1 
ATOM 6230 C C   . GLY C 3 63  ? 158.881 121.615 163.913 1.00 9.59   ? 319 GLY C C   1 
ATOM 6231 O O   . GLY C 3 63  ? 157.761 122.127 163.895 1.00 9.98   ? 319 GLY C O   1 
ATOM 6232 N N   . LEU C 3 64  ? 159.938 122.212 164.461 1.00 9.14   ? 320 LEU C N   1 
ATOM 6233 C CA  . LEU C 3 64  ? 159.860 123.510 165.114 1.00 8.88   ? 320 LEU C CA  1 
ATOM 6234 C C   . LEU C 3 64  ? 159.922 124.648 164.116 1.00 9.15   ? 320 LEU C C   1 
ATOM 6235 O O   . LEU C 3 64  ? 159.317 125.707 164.339 1.00 10.04  ? 320 LEU C O   1 
ATOM 6236 C CB  . LEU C 3 64  ? 160.999 123.672 166.133 1.00 9.26   ? 320 LEU C CB  1 
ATOM 6237 C CG  . LEU C 3 64  ? 160.974 122.771 167.354 1.00 10.15  ? 320 LEU C CG  1 
ATOM 6238 C CD1 . LEU C 3 64  ? 162.348 122.713 168.027 1.00 11.44  ? 320 LEU C CD1 1 
ATOM 6239 C CD2 . LEU C 3 64  ? 159.909 123.240 168.343 1.00 11.15  ? 320 LEU C CD2 1 
ATOM 6240 N N   . ASN C 3 65  ? 160.692 124.500 163.044 1.00 9.89   ? 321 ASN C N   1 
ATOM 6241 C CA  . ASN C 3 65  ? 160.824 125.595 162.105 1.00 10.42  ? 321 ASN C CA  1 
ATOM 6242 C C   . ASN C 3 65  ? 159.459 125.906 161.498 1.00 10.56  ? 321 ASN C C   1 
ATOM 6243 O O   . ASN C 3 65  ? 158.778 125.014 160.977 1.00 12.23  ? 321 ASN C O   1 
ATOM 6244 C CB  . ASN C 3 65  ? 161.826 125.210 161.029 1.00 11.49  ? 321 ASN C CB  1 
ATOM 6245 C CG  . ASN C 3 65  ? 162.350 126.389 160.279 1.00 12.68  ? 321 ASN C CG  1 
ATOM 6246 O OD1 . ASN C 3 65  ? 162.385 127.506 160.782 1.00 12.82  ? 321 ASN C OD1 1 
ATOM 6247 N ND2 . ASN C 3 65  ? 162.810 126.146 159.063 1.00 15.60  ? 321 ASN C ND2 1 
ATOM 6248 N N   . GLY C 3 66  ? 159.043 127.170 161.598 1.00 10.95  ? 322 GLY C N   1 
ATOM 6249 C CA  . GLY C 3 66  ? 157.749 127.591 161.105 1.00 12.59  ? 322 GLY C CA  1 
ATOM 6250 C C   . GLY C 3 66  ? 156.571 127.300 162.010 1.00 11.87  ? 322 GLY C C   1 
ATOM 6251 O O   . GLY C 3 66  ? 155.433 127.589 161.628 1.00 14.98  ? 322 GLY C O   1 
ATOM 6252 N N   . MET C 3 67  ? 156.799 126.740 163.185 1.00 11.39  ? 323 MET C N   1 
ATOM 6253 C CA  . MET C 3 67  ? 155.715 126.468 164.113 0.81 11.18  ? 323 MET C CA  1 
ATOM 6254 C C   . MET C 3 67  ? 155.109 127.777 164.602 1.00 12.10  ? 323 MET C C   1 
ATOM 6255 O O   . MET C 3 67  ? 155.823 128.705 164.968 1.00 12.92  ? 323 MET C O   1 
ATOM 6256 C CB  . MET C 3 67  ? 156.286 125.663 165.282 0.81 12.38  ? 323 MET C CB  1 
ATOM 6257 C CG  . MET C 3 67  ? 155.271 125.214 166.307 0.81 12.24  ? 323 MET C CG  1 
ATOM 6258 S SD  . MET C 3 67  ? 156.044 124.248 167.626 0.81 11.67  ? 323 MET C SD  1 
ATOM 6259 C CE  . MET C 3 67  ? 156.100 122.586 166.920 0.81 12.45  ? 323 MET C CE  1 
ATOM 6260 N N   . GLN C 3 68  ? 153.781 127.827 164.647 0.63 13.69  ? 324 GLN C N   1 
ATOM 6261 C CA  . GLN C 3 68  ? 153.044 129.025 165.027 0.63 14.34  ? 324 GLN C CA  1 
ATOM 6262 C C   . GLN C 3 68  ? 152.629 128.919 166.492 0.63 14.14  ? 324 GLN C C   1 
ATOM 6263 O O   . GLN C 3 68  ? 151.948 127.965 166.886 0.63 14.46  ? 324 GLN C O   1 
ATOM 6264 C CB  . GLN C 3 68  ? 151.808 129.177 164.137 0.63 16.33  ? 324 GLN C CB  1 
ATOM 6265 C CG  . GLN C 3 68  ? 151.145 130.537 164.217 0.63 18.06  ? 324 GLN C CG  1 
ATOM 6266 C CD  . GLN C 3 68  ? 151.875 131.600 163.419 0.63 19.61  ? 324 GLN C CD  1 
ATOM 6267 O OE1 . GLN C 3 68  ? 152.415 131.327 162.343 0.63 22.68  ? 324 GLN C OE1 1 
ATOM 6268 N NE2 . GLN C 3 68  ? 151.915 132.814 163.952 0.63 20.71  ? 324 GLN C NE2 1 
ATOM 6269 N N   . LEU C 3 69  ? 153.010 129.912 167.288 1.00 13.18  ? 325 LEU C N   1 
ATOM 6270 C CA  . LEU C 3 69  ? 152.698 129.967 168.714 1.00 12.98  ? 325 LEU C CA  1 
ATOM 6271 C C   . LEU C 3 69  ? 151.945 131.285 168.925 1.00 13.25  ? 325 LEU C C   1 
ATOM 6272 O O   . LEU C 3 69  ? 152.549 132.321 169.213 1.00 15.32  ? 325 LEU C O   1 
ATOM 6273 C CB  . LEU C 3 69  ? 153.984 129.898 169.532 1.00 13.05  ? 325 LEU C CB  1 
ATOM 6274 C CG  . LEU C 3 69  ? 154.909 128.689 169.281 1.00 14.97  ? 325 LEU C CG  1 
ATOM 6275 C CD1 . LEU C 3 69  ? 156.200 128.844 170.060 1.00 17.35  ? 325 LEU C CD1 1 
ATOM 6276 C CD2 . LEU C 3 69  ? 154.244 127.373 169.621 1.00 15.41  ? 325 LEU C CD2 1 
ATOM 6277 N N   . GLY C 3 70  ? 150.631 131.267 168.712 1.00 14.04  ? 326 GLY C N   1 
ATOM 6278 C CA  . GLY C 3 70  ? 149.872 132.510 168.758 1.00 15.44  ? 326 GLY C CA  1 
ATOM 6279 C C   . GLY C 3 70  ? 150.292 133.434 167.626 1.00 15.68  ? 326 GLY C C   1 
ATOM 6280 O O   . GLY C 3 70  ? 150.328 133.037 166.457 1.00 16.10  ? 326 GLY C O   1 
ATOM 6281 N N   . ASP C 3 71  ? 150.623 134.685 167.956 1.00 18.06  ? 327 ASP C N   1 
ATOM 6282 C CA  . ASP C 3 71  ? 151.044 135.650 166.942 1.00 20.59  ? 327 ASP C CA  1 
ATOM 6283 C C   . ASP C 3 71  ? 152.527 135.554 166.584 1.00 19.04  ? 327 ASP C C   1 
ATOM 6284 O O   . ASP C 3 71  ? 153.026 136.416 165.857 1.00 20.47  ? 327 ASP C O   1 
ATOM 6285 C CB  . ASP C 3 71  ? 150.680 137.082 167.358 1.00 27.26  ? 327 ASP C CB  1 
ATOM 6286 C CG  . ASP C 3 71  ? 151.328 137.506 168.668 1.00 35.30  ? 327 ASP C CG  1 
ATOM 6287 O OD1 . ASP C 3 71  ? 152.185 136.768 169.190 1.00 38.15  ? 327 ASP C OD1 1 
ATOM 6288 O OD2 . ASP C 3 71  ? 150.975 138.597 169.174 1.00 39.55  ? 327 ASP C OD2 1 
ATOM 6289 N N   . LYS C 3 72  ? 153.233 134.538 167.058 1.00 15.79  ? 328 LYS C N   1 
ATOM 6290 C CA  . LYS C 3 72  ? 154.643 134.360 166.778 1.00 15.21  ? 328 LYS C CA  1 
ATOM 6291 C C   . LYS C 3 72  ? 154.841 133.108 165.937 1.00 14.91  ? 328 LYS C C   1 
ATOM 6292 O O   . LYS C 3 72  ? 154.072 132.154 166.035 1.00 16.82  ? 328 LYS C O   1 
ATOM 6293 C CB  . LYS C 3 72  ? 155.422 134.165 168.078 1.00 19.52  ? 328 LYS C CB  1 
ATOM 6294 C CG  . LYS C 3 72  ? 155.272 135.285 169.095 1.00 23.78  ? 328 LYS C CG  1 
ATOM 6295 C CD  . LYS C 3 72  ? 155.964 136.561 168.660 1.00 28.11  ? 328 LYS C CD  1 
ATOM 6296 C CE  . LYS C 3 72  ? 157.480 136.438 168.751 1.00 32.79  ? 328 LYS C CE  1 
ATOM 6297 N NZ  . LYS C 3 72  ? 158.174 137.738 168.510 1.00 36.51  ? 328 LYS C NZ  1 
ATOM 6298 N N   . LYS C 3 73  ? 155.913 133.112 165.149 0.59 15.43  ? 329 LYS C N   1 
ATOM 6299 C CA  . LYS C 3 73  ? 156.313 131.986 164.313 0.59 15.95  ? 329 LYS C CA  1 
ATOM 6300 C C   . LYS C 3 73  ? 157.781 131.685 164.579 0.59 13.74  ? 329 LYS C C   1 
ATOM 6301 O O   . LYS C 3 73  ? 158.627 132.578 164.464 0.59 15.63  ? 329 LYS C O   1 
ATOM 6302 C CB  . LYS C 3 73  ? 156.128 132.377 162.843 0.59 19.45  ? 329 LYS C CB  1 
ATOM 6303 C CG  . LYS C 3 73  ? 156.363 131.272 161.834 0.59 20.78  ? 329 LYS C CG  1 
ATOM 6304 C CD  . LYS C 3 73  ? 156.252 131.826 160.414 0.59 24.55  ? 329 LYS C CD  1 
ATOM 6305 C CE  . LYS C 3 73  ? 156.611 130.798 159.348 0.59 27.58  ? 329 LYS C CE  1 
ATOM 6306 N NZ  . LYS C 3 73  ? 155.507 129.836 159.086 0.59 30.88  ? 329 LYS C NZ  1 
ATOM 6307 N N   . LEU C 3 74  ? 158.097 130.429 164.909 1.00 11.51  ? 330 LEU C N   1 
ATOM 6308 C CA  . LEU C 3 74  ? 159.475 130.083 165.211 1.00 10.56  ? 330 LEU C CA  1 
ATOM 6309 C C   . LEU C 3 74  ? 160.293 130.009 163.937 1.00 10.54  ? 330 LEU C C   1 
ATOM 6310 O O   . LEU C 3 74  ? 159.826 129.555 162.891 1.00 11.75  ? 330 LEU C O   1 
ATOM 6311 C CB  . LEU C 3 74  ? 159.582 128.727 165.906 1.00 10.60  ? 330 LEU C CB  1 
ATOM 6312 C CG  . LEU C 3 74  ? 158.886 128.593 167.246 1.00 11.44  ? 330 LEU C CG  1 
ATOM 6313 C CD1 . LEU C 3 74  ? 159.175 127.219 167.838 1.00 12.50  ? 330 LEU C CD1 1 
ATOM 6314 C CD2 . LEU C 3 74  ? 159.319 129.693 168.193 1.00 13.32  ? 330 LEU C CD2 1 
ATOM 6315 N N   . LEU C 3 75  ? 161.544 130.417 164.061 1.00 10.44  ? 331 LEU C N   1 
ATOM 6316 C CA  . LEU C 3 75  ? 162.552 130.249 163.027 1.00 10.73  ? 331 LEU C CA  1 
ATOM 6317 C C   . LEU C 3 75  ? 163.690 129.469 163.671 1.00 10.26  ? 331 LEU C C   1 
ATOM 6318 O O   . LEU C 3 75  ? 164.222 129.894 164.699 1.00 10.59  ? 331 LEU C O   1 
ATOM 6319 C CB  . LEU C 3 75  ? 163.022 131.612 162.512 1.00 12.63  ? 331 LEU C CB  1 
ATOM 6320 C CG  . LEU C 3 75  ? 164.059 131.563 161.400 1.00 14.91  ? 331 LEU C CG  1 
ATOM 6321 C CD1 . LEU C 3 75  ? 163.545 130.831 160.165 1.00 16.17  ? 331 LEU C CD1 1 
ATOM 6322 C CD2 . LEU C 3 75  ? 164.458 132.968 161.049 1.00 16.49  ? 331 LEU C CD2 1 
ATOM 6323 N N   . VAL C 3 76  ? 164.033 128.311 163.111 1.00 10.56  ? 332 VAL C N   1 
ATOM 6324 C CA  . VAL C 3 76  ? 164.982 127.405 163.742 1.00 10.32  ? 332 VAL C CA  1 
ATOM 6325 C C   . VAL C 3 76  ? 166.035 126.993 162.732 1.00 11.58  ? 332 VAL C C   1 
ATOM 6326 O O   . VAL C 3 76  ? 165.712 126.681 161.582 1.00 13.21  ? 332 VAL C O   1 
ATOM 6327 C CB  . VAL C 3 76  ? 164.266 126.161 164.293 1.00 11.08  ? 332 VAL C CB  1 
ATOM 6328 C CG1 . VAL C 3 76  ? 165.258 125.220 164.977 1.00 11.86  ? 332 VAL C CG1 1 
ATOM 6329 C CG2 . VAL C 3 76  ? 163.169 126.570 165.233 1.00 11.71  ? 332 VAL C CG2 1 
ATOM 6330 N N   . GLN C 3 77  ? 167.278 126.896 163.181 0.51 11.31  ? 333 GLN C N   1 
ATOM 6331 C CA  . GLN C 3 77  ? 168.349 126.383 162.345 0.51 11.38  ? 333 GLN C CA  1 
ATOM 6332 C C   . GLN C 3 77  ? 169.292 125.559 163.201 0.51 11.49  ? 333 GLN C C   1 
ATOM 6333 O O   . GLN C 3 77  ? 169.266 125.613 164.434 0.51 10.25  ? 333 GLN C O   1 
ATOM 6334 C CB  . GLN C 3 77  ? 169.144 127.509 161.694 0.51 10.28  ? 333 GLN C CB  1 
ATOM 6335 C CG  . GLN C 3 77  ? 169.851 128.373 162.726 0.51 9.21   ? 333 GLN C CG  1 
ATOM 6336 C CD  . GLN C 3 77  ? 170.710 129.442 162.117 0.51 9.64   ? 333 GLN C CD  1 
ATOM 6337 O OE1 . GLN C 3 77  ? 170.211 130.463 161.641 0.51 10.07  ? 333 GLN C OE1 1 
ATOM 6338 N NE2 . GLN C 3 77  ? 172.019 129.233 162.149 0.51 10.96  ? 333 GLN C NE2 1 
ATOM 6339 N N   . ARG C 3 78  ? 170.131 124.785 162.518 0.51 13.69  ? 334 ARG C N   1 
ATOM 6340 C CA  . ARG C 3 78  ? 171.284 124.175 163.154 0.51 13.48  ? 334 ARG C CA  1 
ATOM 6341 C C   . ARG C 3 78  ? 172.296 125.254 163.529 0.51 14.22  ? 334 ARG C C   1 
ATOM 6342 O O   . ARG C 3 78  ? 172.438 126.269 162.844 0.51 13.77  ? 334 ARG C O   1 
ATOM 6343 C CB  . ARG C 3 78  ? 171.909 123.150 162.209 0.51 14.90  ? 334 ARG C CB  1 
ATOM 6344 C CG  . ARG C 3 78  ? 170.955 122.018 161.911 0.51 16.19  ? 334 ARG C CG  1 
ATOM 6345 C CD  . ARG C 3 78  ? 171.466 121.062 160.855 0.51 16.53  ? 334 ARG C CD  1 
ATOM 6346 N NE  . ARG C 3 78  ? 170.571 119.913 160.691 0.51 14.78  ? 334 ARG C NE  1 
ATOM 6347 C CZ  . ARG C 3 78  ? 169.460 119.919 159.954 0.51 15.37  ? 334 ARG C CZ  1 
ATOM 6348 N NH1 . ARG C 3 78  ? 169.104 121.011 159.289 0.51 18.05  ? 334 ARG C NH1 1 
ATOM 6349 N NH2 . ARG C 3 78  ? 168.707 118.828 159.879 0.51 15.74  ? 334 ARG C NH2 1 
ATOM 6350 N N   . ALA C 3 79  ? 172.981 125.037 164.651 0.51 16.20  ? 335 ALA C N   1 
ATOM 6351 C CA  . ALA C 3 79  ? 173.901 126.018 165.224 0.51 24.07  ? 335 ALA C CA  1 
ATOM 6352 C C   . ALA C 3 79  ? 175.309 125.701 164.730 0.51 34.08  ? 335 ALA C C   1 
ATOM 6353 O O   . ALA C 3 79  ? 176.119 125.071 165.410 0.51 34.99  ? 335 ALA C O   1 
ATOM 6354 C CB  . ALA C 3 79  ? 173.815 125.992 166.743 0.51 22.97  ? 335 ALA C CB  1 
ATOM 6355 N N   . SER C 3 80  ? 175.601 126.177 163.522 0.51 43.19  ? 336 SER C N   1 
ATOM 6356 C CA  . SER C 3 80  ? 176.824 125.821 162.803 0.51 51.05  ? 336 SER C CA  1 
ATOM 6357 C C   . SER C 3 80  ? 178.111 126.181 163.548 0.51 56.26  ? 336 SER C C   1 
ATOM 6358 O O   . SER C 3 80  ? 179.166 126.333 162.931 0.51 58.31  ? 336 SER C O   1 
ATOM 6359 C CB  . SER C 3 80  ? 176.821 126.500 161.432 0.51 52.29  ? 336 SER C CB  1 
ATOM 6360 O OG  . SER C 3 80  ? 176.856 127.911 161.569 0.51 52.69  ? 336 SER C OG  1 
ATOM 6361 O OXT . SER C 3 80  ? 178.147 126.330 164.769 0.51 57.92  ? 336 SER C OXT 1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
5754 N N   . SER C 1  ? 0.6420 0.5601 0.3467 -0.0500 -0.0205 0.0367  257 SER C N   
5755 C CA  . SER C 1  ? 0.5925 0.5032 0.3390 -0.0808 -0.0337 0.0448  257 SER C CA  
5756 C C   . SER C 1  ? 0.4904 0.3991 0.3015 -0.1548 -0.0472 -0.0011 257 SER C C   
5757 O O   . SER C 1  ? 0.4411 0.3391 0.2859 -0.1901 -0.0498 0.0294  257 SER C O   
5758 C CB  . SER C 1  ? 0.6144 0.5613 0.3558 -0.0091 -0.0194 0.0836  257 SER C CB  
5759 O OG  . SER C 1  ? 0.6118 0.5730 0.3617 0.0352  -0.0029 0.1196  257 SER C OG  
5760 N N   . ALA C 2  ? 0.4401 0.3804 0.2786 -0.1533 -0.0571 -0.0314 258 ALA C N   
5761 C CA  . ALA C 2  ? 0.3616 0.3444 0.2450 -0.1113 -0.0634 -0.0610 258 ALA C CA  
5762 C C   . ALA C 2  ? 0.2526 0.2890 0.1545 -0.0891 -0.0247 -0.0583 258 ALA C C   
5763 O O   . ALA C 2  ? 0.2031 0.3639 0.1793 -0.0452 -0.0270 -0.0789 258 ALA C O   
5764 C CB  . ALA C 2  ? 0.4213 0.3913 0.2883 -0.1156 -0.1234 -0.0963 258 ALA C CB  
5765 N N   . HIS C 3  ? 0.1878 0.2178 0.0788 -0.0280 0.0250  -0.0187 259 HIS C N   
5766 C CA  . HIS C 3  ? 0.1482 0.1794 0.0587 0.0106  0.0106  -0.0007 259 HIS C CA  
5767 C C   . HIS C 3  ? 0.1473 0.1626 0.0551 0.0059  0.0174  -0.0101 259 HIS C C   
5768 O O   . HIS C 3  ? 0.1820 0.1767 0.0569 -0.0158 0.0231  -0.0011 259 HIS C O   
5769 C CB  . HIS C 3  ? 0.1361 0.2264 0.0587 -0.0076 0.0103  -0.0100 259 HIS C CB  
5770 C CG  . HIS C 3  ? 0.1412 0.2633 0.0764 -0.0151 0.0157  -0.0346 259 HIS C CG  
5771 N ND1 . HIS C 3  ? 0.1602 0.2669 0.0801 -0.0383 0.0234  -0.0311 259 HIS C ND1 
5772 C CD2 . HIS C 3  ? 0.1884 0.3283 0.0939 -0.0589 0.0244  -0.0150 259 HIS C CD2 
5773 C CE1 . HIS C 3  ? 0.1649 0.2860 0.0891 -0.0508 0.0314  -0.0254 259 HIS C CE1 
5774 N NE2 . HIS C 3  ? 0.1938 0.3246 0.0922 -0.0517 0.0233  -0.0227 259 HIS C NE2 
5775 N N   . LYS C 4  ? 0.1666 0.1681 0.0548 -0.0157 0.0062  0.0012  260 LYS C N   
5776 C CA  . LYS C 4  ? 0.1628 0.1853 0.0561 -0.0138 0.0107  0.0151  260 LYS C CA  
5777 C C   . LYS C 4  ? 0.1486 0.2041 0.0591 -0.0243 0.0106  0.0218  260 LYS C C   
5778 O O   . LYS C 4  ? 0.1488 0.2334 0.0683 -0.0348 0.0174  -0.0024 260 LYS C O   
5779 C CB  . LYS C 4  ? 0.1845 0.2234 0.0777 -0.0092 0.0109  0.0215  260 LYS C CB  
5780 C CG  . LYS C 4  ? 0.2120 0.2133 0.1284 0.0213  0.0051  0.0230  260 LYS C CG  
5781 C CD  . LYS C 4  ? 0.2654 0.3142 0.2043 0.0864  0.0023  0.0043  260 LYS C CD  
5782 C CE  . LYS C 4  ? 0.3856 0.4549 0.2578 0.1116  -0.0094 0.0029  260 LYS C CE  
5783 N NZ  . LYS C 4  ? 0.4641 0.5485 0.2778 0.0772  -0.0143 -0.0126 260 LYS C NZ  
5784 N N   . LEU C 5  ? 0.1487 0.1909 0.0492 -0.0017 0.0080  0.0096  261 LEU C N   
5785 C CA  . LEU C 5  ? 0.1598 0.1950 0.0583 -0.0047 0.0283  0.0154  261 LEU C CA  
5786 C C   . LEU C 5  ? 0.1319 0.1832 0.0543 -0.0221 0.0089  -0.0034 261 LEU C C   
5787 O O   . LEU C 5  ? 0.1388 0.2093 0.0606 -0.0202 0.0131  0.0142  261 LEU C O   
5788 C CB  . LEU C 5  ? 0.1971 0.2084 0.1131 0.0109  0.0564  0.0417  261 LEU C CB  
5789 C CG  . LEU C 5  ? 0.1501 0.2461 0.2129 0.0097  0.0276  0.0670  261 LEU C CG  
5790 C CD1 . LEU C 5  ? 0.1610 0.2707 0.2789 -0.0039 0.0633  0.0867  261 LEU C CD1 
5791 C CD2 . LEU C 5  ? 0.2308 0.2700 0.1944 0.0393  0.0797  0.0740  261 LEU C CD2 
5792 N N   . PHE C 6  ? 0.1286 0.1834 0.0523 -0.0207 0.0178  -0.0025 262 PHE C N   
5793 C CA  . PHE C 6  ? 0.1343 0.1683 0.0482 -0.0143 0.0095  0.0077  262 PHE C CA  
5794 C C   . PHE C 6  ? 0.1290 0.1633 0.0485 -0.0038 0.0013  0.0019  262 PHE C C   
5795 O O   . PHE C 6  ? 0.1404 0.1787 0.0719 -0.0162 0.0015  -0.0072 262 PHE C O   
5796 C CB  . PHE C 6  ? 0.1307 0.1848 0.0683 -0.0198 0.0019  0.0072  262 PHE C CB  
5797 C CG  . PHE C 6  ? 0.1616 0.1653 0.0773 -0.0178 0.0123  -0.0008 262 PHE C CG  
5798 C CD1 . PHE C 6  ? 0.1689 0.1981 0.0789 -0.0181 0.0145  0.0240  262 PHE C CD1 
5799 C CD2 . PHE C 6  ? 0.1572 0.1666 0.1024 -0.0204 0.0122  0.0059  262 PHE C CD2 
5800 C CE1 . PHE C 6  ? 0.1840 0.2116 0.0847 -0.0224 0.0109  0.0097  262 PHE C CE1 
5801 C CE2 . PHE C 6  ? 0.1817 0.1874 0.1118 -0.0172 0.0237  0.0106  262 PHE C CE2 
5802 C CZ  . PHE C 6  ? 0.2105 0.1765 0.1011 -0.0090 0.0338  0.0162  262 PHE C CZ  
5803 N N   . ILE C 7  ? 0.1294 0.1713 0.0510 -0.0163 0.0018  -0.0031 263 ILE C N   
5804 C CA  . ILE C 7  ? 0.1255 0.1632 0.0529 -0.0084 -0.0012 -0.0059 263 ILE C CA  
5805 C C   . ILE C 7  ? 0.1488 0.1582 0.0587 -0.0074 0.0007  0.0007  263 ILE C C   
5806 O O   . ILE C 7  ? 0.1467 0.1928 0.0564 -0.0064 0.0018  0.0042  263 ILE C O   
5807 C CB  . ILE C 7  ? 0.1377 0.1651 0.0723 -0.0200 0.0067  0.0049  263 ILE C CB  
5808 C CG1 . ILE C 7  ? 0.1464 0.1756 0.0917 -0.0146 0.0124  0.0142  263 ILE C CG1 
5809 C CG2 . ILE C 7  ? 0.1679 0.1759 0.0890 -0.0214 0.0008  0.0002  263 ILE C CG2 
5810 C CD1 . ILE C 7  ? 0.2268 0.2647 0.1199 -0.0772 0.0092  0.0441  263 ILE C CD1 
5811 N N   . GLY C 8  ? 0.1443 0.1728 0.0586 -0.0076 0.0036  0.0000  264 GLY C N   
5812 C CA  . GLY C 8  ? 0.1594 0.1717 0.0648 -0.0158 0.0093  0.0042  264 GLY C CA  
5813 C C   . GLY C 8  ? 0.1395 0.1708 0.0580 -0.0236 0.0126  -0.0046 264 GLY C C   
5814 O O   . GLY C 8  ? 0.1744 0.1785 0.0664 -0.0010 -0.0002 0.0019  264 GLY C O   
5815 N N   . GLY C 9  ? 0.1740 0.1843 0.0559 -0.0119 0.0015  0.0004  265 GLY C N   
5816 C CA  . GLY C 9  ? 0.1815 0.1982 0.0634 -0.0024 0.0185  -0.0098 265 GLY C CA  
5817 C C   . GLY C 9  ? 0.2090 0.1863 0.0645 0.0104  0.0075  -0.0089 265 GLY C C   
5818 O O   . GLY C 9  ? 0.2127 0.2103 0.0949 0.0076  0.0054  -0.0146 265 GLY C O   
5819 N N   . LEU C 10 ? 0.1810 0.1736 0.0658 0.0089  -0.0061 -0.0113 266 LEU C N   
5820 C CA  . LEU C 10 ? 0.2005 0.1624 0.0756 -0.0004 -0.0269 0.0001  266 LEU C CA  
5821 C C   . LEU C 10 ? 0.2307 0.1742 0.0717 0.0054  -0.0271 -0.0049 266 LEU C C   
5822 O O   . LEU C 10 ? 0.2827 0.1769 0.0762 0.0128  -0.0290 0.0035  266 LEU C O   
5823 C CB  . LEU C 10 ? 0.1881 0.1740 0.0879 -0.0069 -0.0288 0.0061  266 LEU C CB  
5824 C CG  . LEU C 10 ? 0.1421 0.1889 0.1011 -0.0093 -0.0137 0.0055  266 LEU C CG  
5825 C CD1 . LEU C 10 ? 0.1785 0.1980 0.1227 -0.0071 0.0020  0.0017  266 LEU C CD1 
5826 C CD2 . LEU C 10 ? 0.1820 0.1958 0.1107 -0.0098 -0.0233 0.0211  266 LEU C CD2 
5827 N N   . PRO C 11 ? 0.2408 0.1765 0.0772 -0.0012 -0.0302 -0.0146 267 PRO C N   
5828 C CA  . PRO C 11 ? 0.2567 0.1945 0.0854 0.0054  -0.0315 -0.0222 267 PRO C CA  
5829 C C   . PRO C 11 ? 0.2581 0.1982 0.0819 -0.0038 -0.0321 0.0016  267 PRO C C   
5830 O O   . PRO C 11 ? 0.2555 0.2117 0.0832 -0.0062 -0.0465 0.0033  267 PRO C O   
5831 C CB  . PRO C 11 ? 0.2910 0.2031 0.1109 -0.0064 -0.0442 -0.0314 267 PRO C CB  
5832 C CG  . PRO C 11 ? 0.2980 0.1936 0.1196 0.0076  -0.0459 -0.0147 267 PRO C CG  
5833 C CD  . PRO C 11 ? 0.2727 0.1631 0.0981 0.0125  -0.0494 -0.0083 267 PRO C CD  
5834 N N   . ASN C 12 ? 0.2736 0.2052 0.0908 0.0200  -0.0265 0.0156  268 ASN C N   
5835 C CA  . ASN C 12 ? 0.2924 0.2010 0.0950 -0.0127 -0.0377 0.0227  268 ASN C CA  
5836 C C   . ASN C 12 ? 0.2684 0.2023 0.1148 0.0083  -0.0691 0.0194  268 ASN C C   
5837 O O   . ASN C 12 ? 0.2943 0.2241 0.2030 0.0280  -0.0745 -0.0152 268 ASN C O   
5838 C CB  . ASN C 12 ? 0.3908 0.2623 0.1053 -0.0348 -0.0151 0.0130  268 ASN C CB  
5839 C CG  . ASN C 12 ? 0.4753 0.3097 0.1231 -0.0517 0.0103  0.0046  268 ASN C CG  
5840 O OD1 . ASN C 12 ? 0.5143 0.3144 0.1344 -0.0709 0.0058  0.0027  268 ASN C OD1 
5841 N ND2 . ASN C 12 ? 0.5120 0.3416 0.1340 -0.0598 0.0196  -0.0013 268 ASN C ND2 
5842 N N   . TYR C 13 ? 0.2785 0.1855 0.0958 0.0061  -0.0651 0.0004  269 TYR C N   
5843 C CA  . TYR C 13 ? 0.2853 0.1964 0.0986 0.0344  -0.0599 -0.0011 269 TYR C CA  
5844 C C   . TYR C 13 ? 0.2622 0.1935 0.1079 0.0071  -0.0669 0.0080  269 TYR C C   
5845 O O   . TYR C 13 ? 0.2534 0.2212 0.1240 0.0153  -0.0714 -0.0042 269 TYR C O   
5846 C CB  . TYR C 13 ? 0.2955 0.1983 0.0937 0.0175  -0.0557 -0.0152 269 TYR C CB  
5847 C CG  . TYR C 13 ? 0.2861 0.1972 0.0878 0.0219  -0.0497 -0.0107 269 TYR C CG  
5848 C CD1 . TYR C 13 ? 0.2846 0.2037 0.1242 -0.0011 -0.0339 0.0273  269 TYR C CD1 
5849 C CD2 . TYR C 13 ? 0.2619 0.2085 0.0981 0.0089  -0.0242 -0.0095 269 TYR C CD2 
5850 C CE1 . TYR C 13 ? 0.2737 0.2503 0.1414 0.0267  -0.0056 0.0467  269 TYR C CE1 
5851 C CE2 . TYR C 13 ? 0.2597 0.2299 0.1215 0.0142  -0.0160 0.0171  269 TYR C CE2 
5852 C CZ  . TYR C 13 ? 0.2705 0.2519 0.1430 0.0500  0.0069  0.0641  269 TYR C CZ  
5853 O OH  . TYR C 13 ? 0.3010 0.3405 0.2075 0.1053  0.0388  0.1146  269 TYR C OH  
5854 N N   . LEU C 14 ? 0.2530 0.1867 0.0952 -0.0039 -0.0593 0.0112  270 LEU C N   
5855 C CA  . LEU C 14 ? 0.2676 0.1870 0.0965 -0.0296 -0.0579 0.0137  270 LEU C CA  
5856 C C   . LEU C 14 ? 0.2393 0.1833 0.1149 -0.0398 -0.0508 0.0149  270 LEU C C   
5857 O O   . LEU C 14 ? 0.2407 0.1957 0.1390 -0.0217 -0.0473 0.0025  270 LEU C O   
5858 C CB  . LEU C 14 ? 0.2638 0.2015 0.1028 -0.0222 -0.0529 0.0077  270 LEU C CB  
5859 C CG  . LEU C 14 ? 0.2701 0.2057 0.1248 0.0130  -0.0520 0.0062  270 LEU C CG  
5860 C CD1 . LEU C 14 ? 0.2823 0.2476 0.1507 0.0184  -0.0635 0.0111  270 LEU C CD1 
5861 C CD2 . LEU C 14 ? 0.2827 0.1964 0.1357 -0.0040 -0.0402 -0.0011 270 LEU C CD2 
5862 N N   . ASN C 15 ? 0.2460 0.1998 0.1171 -0.0302 -0.0653 0.0150  271 ASN C N   
5863 C CA  . ASN C 15 ? 0.2319 0.2214 0.1345 -0.0361 -0.0637 0.0364  271 ASN C CA  
5864 C C   . ASN C 15 ? 0.1896 0.2139 0.1470 -0.0356 -0.0740 0.0336  271 ASN C C   
5865 O O   . ASN C 15 ? 0.1821 0.2056 0.1334 -0.0345 -0.0658 0.0257  271 ASN C O   
5866 C CB  . ASN C 15 ? 0.2234 0.2816 0.1480 -0.0511 -0.0804 0.0350  271 ASN C CB  
5867 C CG  . ASN C 15 ? 0.2777 0.2923 0.1623 -0.0888 -0.0966 0.0242  271 ASN C CG  
5868 O OD1 . ASN C 15 ? 0.2507 0.3006 0.1478 -0.0960 -0.0811 0.0396  271 ASN C OD1 
5869 N ND2 . ASN C 15 ? 0.3433 0.3207 0.1909 -0.1178 -0.1102 0.0097  271 ASN C ND2 
5870 N N   . ASP C 16 ? 0.1822 0.2363 0.1678 -0.0127 -0.0719 0.0524  272 ASP C N   
5871 C CA  . ASP C 16 ? 0.1655 0.2306 0.1844 -0.0209 -0.0615 0.0432  272 ASP C CA  
5872 C C   . ASP C 16 ? 0.1630 0.2419 0.1683 -0.0291 -0.0547 0.0385  272 ASP C C   
5873 O O   . ASP C 16 ? 0.1684 0.2304 0.1561 -0.0117 -0.0524 0.0218  272 ASP C O   
5874 C CB  . ASP C 16 ? 0.1714 0.2539 0.2290 0.0000  -0.0414 0.0401  272 ASP C CB  
5875 C CG  . ASP C 16 ? 0.2154 0.2808 0.2481 -0.0037 -0.0127 0.0493  272 ASP C CG  
5876 O OD1 . ASP C 16 ? 0.2201 0.2698 0.2379 -0.0221 -0.0230 0.0589  272 ASP C OD1 
5877 O OD2 . ASP C 16 ? 0.3285 0.3189 0.2839 0.0285  0.0235  0.0258  272 ASP C OD2 
5878 N N   . ASP C 17 ? 0.1695 0.2640 0.1698 -0.0613 -0.0676 0.0490  273 ASP C N   
5879 C CA  . ASP C 17 ? 0.1808 0.2863 0.1737 -0.0653 -0.0767 0.0567  273 ASP C CA  
5880 C C   . ASP C 17 ? 0.1866 0.2451 0.1323 -0.0787 -0.0594 0.0412  273 ASP C C   
5881 O O   . ASP C 17 ? 0.1750 0.2374 0.1399 -0.0513 -0.0521 0.0329  273 ASP C O   
5882 C CB  . ASP C 17 ? 0.1872 0.3870 0.2373 -0.0998 -0.0836 0.0669  273 ASP C CB  
5883 C CG  . ASP C 17 ? 0.2242 0.5554 0.2964 -0.1196 -0.0854 0.0567  273 ASP C CG  
5884 O OD1 . ASP C 17 ? 0.2665 0.6692 0.3193 -0.0585 -0.0768 0.0512  273 ASP C OD1 
5885 O OD2 . ASP C 17 ? 0.2880 0.6740 0.3324 -0.0945 -0.1006 0.0463  273 ASP C OD2 
5886 N N   . GLN C 18 ? 0.1845 0.2179 0.1110 -0.0522 -0.0501 0.0219  274 GLN C N   
5887 C CA  . GLN C 18 ? 0.1869 0.1933 0.1045 -0.0442 -0.0513 -0.0008 274 GLN C CA  
5888 C C   . GLN C 18 ? 0.1809 0.1947 0.1037 -0.0259 -0.0264 0.0061  274 GLN C C   
5889 O O   . GLN C 18 ? 0.1586 0.1746 0.1102 -0.0117 -0.0205 0.0003  274 GLN C O   
5890 C CB  . GLN C 18 ? 0.2274 0.1924 0.1116 -0.0505 -0.0515 -0.0084 274 GLN C CB  
5891 C CG  . GLN C 18 ? 0.2826 0.2188 0.1094 -0.0809 -0.0519 0.0050  274 GLN C CG  
5892 C CD  . GLN C 18 ? 0.2675 0.2157 0.1129 -0.0563 -0.0367 -0.0054 274 GLN C CD  
5893 O OE1 . GLN C 18 ? 0.2855 0.2216 0.1013 -0.0627 -0.0292 -0.0107 274 GLN C OE1 
5894 N NE2 . GLN C 18 ? 0.2546 0.2020 0.1328 -0.0418 -0.0340 -0.0119 274 GLN C NE2 
5895 N N   . VAL C 19 ? 0.1601 0.1900 0.1034 -0.0375 -0.0360 0.0149  275 VAL C N   
5896 C CA  . VAL C 19 ? 0.1498 0.1863 0.1109 -0.0146 -0.0393 0.0039  275 VAL C CA  
5897 C C   . VAL C 19 ? 0.1423 0.1853 0.1077 -0.0159 -0.0452 0.0030  275 VAL C C   
5898 O O   . VAL C 19 ? 0.1450 0.1985 0.0995 -0.0161 -0.0328 -0.0032 275 VAL C O   
5899 C CB  . VAL C 19 ? 0.1751 0.1856 0.1212 -0.0348 -0.0456 0.0146  275 VAL C CB  
5900 C CG1 . VAL C 19 ? 0.1817 0.1889 0.1266 -0.0450 -0.0272 0.0025  275 VAL C CG1 
5901 C CG2 . VAL C 19 ? 0.1910 0.2037 0.1240 -0.0448 -0.0604 0.0254  275 VAL C CG2 
5902 N N   . LYS C 20 ? 0.1404 0.1954 0.1257 -0.0010 -0.0400 -0.0098 276 LYS C N   
5903 C CA  . LYS C 20 ? 0.1380 0.2249 0.1451 0.0143  -0.0309 -0.0191 276 LYS C CA  
5904 C C   . LYS C 20 ? 0.1055 0.2034 0.1227 0.0046  -0.0233 -0.0347 276 LYS C C   
5905 O O   . LYS C 20 ? 0.0888 0.1991 0.1217 0.0236  -0.0333 -0.0360 276 LYS C O   
5906 C CB  . LYS C 20 ? 0.2016 0.2998 0.1874 0.0475  -0.0041 0.0001  276 LYS C CB  
5907 C CG  . LYS C 20 ? 0.2381 0.3257 0.1950 0.0493  -0.0063 0.0113  276 LYS C CG  
5908 C CD  . LYS C 20 ? 0.2542 0.3900 0.2178 0.0566  -0.0078 -0.0015 276 LYS C CD  
5909 C CE  . LYS C 20 ? 0.2298 0.4432 0.2497 0.0644  -0.0339 -0.0143 276 LYS C CE  
5910 N NZ  . LYS C 20 ? 0.1930 0.4745 0.2681 0.0653  -0.0529 -0.0180 276 LYS C NZ  
5911 N N   . GLU C 21 ? 0.1319 0.2049 0.1108 -0.0164 -0.0213 -0.0168 277 GLU C N   
5912 C CA  . GLU C 21 ? 0.1449 0.2053 0.1040 -0.0209 -0.0075 -0.0092 277 GLU C CA  
5913 C C   . GLU C 21 ? 0.1390 0.1994 0.0996 -0.0309 0.0037  -0.0258 277 GLU C C   
5914 O O   . GLU C 21 ? 0.1519 0.2133 0.1105 -0.0087 -0.0035 0.0037  277 GLU C O   
5915 C CB  . GLU C 21 ? 0.1486 0.2049 0.1369 -0.0249 0.0028  -0.0084 277 GLU C CB  
5916 C CG  . GLU C 21 ? 0.1796 0.2223 0.1756 -0.0122 0.0265  -0.0339 277 GLU C CG  
5917 C CD  . GLU C 21 ? 0.2254 0.3481 0.2457 -0.0431 0.0608  -0.0787 277 GLU C CD  
5918 O OE1 . GLU C 21 ? 0.2528 0.4198 0.2909 -0.0337 0.0611  -0.1115 277 GLU C OE1 
5919 O OE2 . GLU C 21 ? 0.2385 0.3698 0.2763 -0.0260 0.0605  -0.0962 277 GLU C OE2 
5920 N N   . LEU C 22 ? 0.1354 0.1851 0.0969 -0.0056 -0.0080 -0.0180 278 LEU C N   
5921 C CA  . LEU C 22 ? 0.1206 0.1964 0.1000 0.0028  -0.0022 -0.0266 278 LEU C CA  
5922 C C   . LEU C 22 ? 0.1199 0.2002 0.0884 -0.0010 -0.0006 -0.0180 278 LEU C C   
5923 O O   . LEU C 22 ? 0.1372 0.2036 0.1093 0.0135  -0.0222 -0.0104 278 LEU C O   
5924 C CB  . LEU C 22 ? 0.1384 0.2147 0.1169 0.0002  -0.0027 -0.0314 278 LEU C CB  
5925 C CG  . LEU C 22 ? 0.1267 0.2352 0.1414 -0.0082 0.0047  -0.0268 278 LEU C CG  
5926 C CD1 . LEU C 22 ? 0.1321 0.2589 0.1721 0.0143  0.0127  -0.0136 278 LEU C CD1 
5927 C CD2 . LEU C 22 ? 0.1371 0.2744 0.1573 -0.0216 0.0215  -0.0381 278 LEU C CD2 
5928 N N   . LEU C 23 ? 0.1203 0.1741 0.0861 0.0039  -0.0047 -0.0109 279 LEU C N   
5929 C CA  . LEU C 23 ? 0.1096 0.1864 0.0841 -0.0013 -0.0139 -0.0092 279 LEU C CA  
5930 C C   . LEU C 23 ? 0.1184 0.1806 0.0842 0.0097  -0.0033 -0.0067 279 LEU C C   
5931 O O   . LEU C 23 ? 0.1108 0.2012 0.0778 0.0091  -0.0014 -0.0070 279 LEU C O   
5932 C CB  . LEU C 23 ? 0.1152 0.1903 0.1106 0.0039  -0.0149 -0.0142 279 LEU C CB  
5933 C CG  . LEU C 23 ? 0.1450 0.1946 0.1606 0.0026  -0.0093 0.0076  279 LEU C CG  
5934 C CD1 . LEU C 23 ? 0.1808 0.1941 0.1722 0.0041  -0.0220 0.0089  279 LEU C CD1 
5935 C CD2 . LEU C 23 ? 0.1895 0.2257 0.2013 -0.0257 -0.0304 0.0398  279 LEU C CD2 
5936 N N   . THR C 24 ? 0.1014 0.2030 0.1022 -0.0089 -0.0013 -0.0029 280 THR C N   
5937 C CA  . THR C 24 ? 0.1120 0.2283 0.1173 -0.0107 -0.0044 0.0045  280 THR C CA  
5938 C C   . THR C 24 ? 0.1098 0.2186 0.0963 -0.0022 0.0000  -0.0153 280 THR C C   
5939 O O   . THR C 24 ? 0.1255 0.2366 0.0983 -0.0042 -0.0009 0.0061  280 THR C O   
5940 C CB  . THR C 24 ? 0.1371 0.2570 0.1756 -0.0094 -0.0155 0.0147  280 THR C CB  
5941 O OG1 . THR C 24 ? 0.1741 0.2902 0.1607 -0.0254 0.0051  0.0043  280 THR C OG1 
5942 C CG2 . THR C 24 ? 0.1178 0.2741 0.2469 -0.0124 -0.0327 0.0460  280 THR C CG2 
5943 N N   . SER C 25 ? 0.1297 0.1963 0.1130 -0.0171 -0.0047 -0.0097 281 SER C N   
5944 C CA  . SER C 25 ? 0.1507 0.1994 0.1195 -0.0055 -0.0059 -0.0028 281 SER C CA  
5945 C C   . SER C 25 ? 0.1574 0.1965 0.1404 0.0039  -0.0121 -0.0002 281 SER C C   
5946 O O   . SER C 25 ? 0.2310 0.1850 0.1785 -0.0044 -0.0618 0.0254  281 SER C O   
5947 C CB  . SER C 25 ? 0.1705 0.2062 0.1454 -0.0118 -0.0132 -0.0147 281 SER C CB  
5948 O OG  . SER C 25 ? 0.1520 0.2139 0.1565 0.0133  0.0139  -0.0043 281 SER C OG  
5949 N N   . PHE C 26 ? 0.1153 0.1693 0.1098 -0.0012 0.0065  0.0011  282 PHE C N   
5950 C CA  . PHE C 26 ? 0.1112 0.1931 0.1079 0.0037  -0.0046 0.0038  282 PHE C CA  
5951 C C   . PHE C 26 ? 0.1101 0.1954 0.0980 -0.0010 0.0108  0.0082  282 PHE C C   
5952 O O   . PHE C 26 ? 0.1418 0.2257 0.0990 0.0103  -0.0007 0.0197  282 PHE C O   
5953 C CB  . PHE C 26 ? 0.1061 0.1997 0.1089 0.0057  -0.0009 -0.0064 282 PHE C CB  
5954 C CG  . PHE C 26 ? 0.0923 0.1760 0.1193 0.0000  0.0030  -0.0019 282 PHE C CG  
5955 C CD1 . PHE C 26 ? 0.0953 0.1942 0.1417 -0.0029 0.0034  -0.0054 282 PHE C CD1 
5956 C CD2 . PHE C 26 ? 0.1001 0.1946 0.1183 -0.0004 0.0141  0.0050  282 PHE C CD2 
5957 C CE1 . PHE C 26 ? 0.1055 0.2114 0.1654 0.0183  0.0053  -0.0070 282 PHE C CE1 
5958 C CE2 . PHE C 26 ? 0.1560 0.2008 0.1163 0.0058  0.0188  -0.0022 282 PHE C CE2 
5959 C CZ  . PHE C 26 ? 0.1312 0.1977 0.1482 0.0039  0.0367  -0.0082 282 PHE C CZ  
5960 N N   . GLY C 27 ? 0.1056 0.2071 0.0947 0.0110  0.0042  0.0056  283 GLY C N   
5961 C CA  . GLY C 27 ? 0.0993 0.1933 0.0931 -0.0110 0.0205  0.0078  283 GLY C CA  
5962 C C   . GLY C 27 ? 0.0941 0.1886 0.0874 -0.0119 0.0109  0.0159  283 GLY C C   
5963 O O   . GLY C 27 ? 0.1092 0.2040 0.0843 -0.0113 0.0099  0.0194  283 GLY C O   
5964 N N   . PRO C 28 ? 0.0967 0.2045 0.0869 -0.0019 0.0195  0.0195  284 PRO C N   
5965 C CA  . PRO C 28 ? 0.0916 0.2176 0.1010 -0.0065 0.0112  0.0260  284 PRO C CA  
5966 C C   . PRO C 28 ? 0.0960 0.2013 0.0785 -0.0086 0.0274  0.0167  284 PRO C C   
5967 O O   . PRO C 28 ? 0.0991 0.2028 0.0701 -0.0044 0.0101  0.0034  284 PRO C O   
5968 C CB  . PRO C 28 ? 0.1093 0.2665 0.1317 -0.0082 0.0372  0.0376  284 PRO C CB  
5969 C CG  . PRO C 28 ? 0.1462 0.3298 0.1242 0.0410  0.0476  0.0272  284 PRO C CG  
5970 C CD  . PRO C 28 ? 0.1164 0.2104 0.1018 -0.0045 0.0269  0.0172  284 PRO C CD  
5971 N N   . LEU C 29 ? 0.1197 0.2231 0.0833 -0.0212 -0.0096 0.0153  285 LEU C N   
5972 C CA  . LEU C 29 ? 0.1080 0.2308 0.0774 -0.0238 0.0041  0.0332  285 LEU C CA  
5973 C C   . LEU C 29 ? 0.1133 0.2514 0.0857 -0.0191 0.0071  0.0249  285 LEU C C   
5974 O O   . LEU C 29 ? 0.1168 0.2794 0.1421 -0.0147 0.0157  0.0181  285 LEU C O   
5975 C CB  . LEU C 29 ? 0.1262 0.2251 0.0957 0.0010  -0.0012 0.0271  285 LEU C CB  
5976 C CG  . LEU C 29 ? 0.1357 0.2378 0.0943 0.0225  0.0245  0.0364  285 LEU C CG  
5977 C CD1 . LEU C 29 ? 0.1795 0.2666 0.0956 0.0199  0.0317  0.0306  285 LEU C CD1 
5978 C CD2 . LEU C 29 ? 0.1177 0.2568 0.1322 0.0235  0.0311  0.0396  285 LEU C CD2 
5979 N N   . LYS C 30 ? 0.1671 0.2340 0.0887 -0.0114 0.0553  0.0103  286 LYS C N   
5980 C CA  . LYS C 30 ? 0.1594 0.2349 0.1057 0.0133  0.0673  0.0030  286 LYS C CA  
5981 C C   . LYS C 30 ? 0.1394 0.2941 0.0960 0.0195  0.0299  0.0362  286 LYS C C   
5982 O O   . LYS C 30 ? 0.1371 0.3467 0.1115 0.0074  0.0172  0.0314  286 LYS C O   
5983 C CB  . LYS C 30 ? 0.2345 0.2687 0.1261 0.0186  0.0490  0.0457  286 LYS C CB  
5984 C CG  . LYS C 30 ? 0.2497 0.3054 0.1458 0.0533  0.0041  0.0236  286 LYS C CG  
5985 C CD  . LYS C 30 ? 0.2685 0.3159 0.1524 0.0427  -0.0047 0.0011  286 LYS C CD  
5986 C CE  . LYS C 30 ? 0.2463 0.3004 0.1491 0.0505  -0.0108 -0.0127 286 LYS C CE  
5987 N NZ  . LYS C 30 ? 0.2222 0.2837 0.1520 0.0749  -0.0321 -0.0116 286 LYS C NZ  
5988 N N   . ALA C 31 ? 0.1402 0.2703 0.0800 0.0235  0.0180  0.0366  287 ALA C N   
5989 C CA  . ALA C 31 ? 0.1596 0.2573 0.0879 0.0375  0.0154  0.0321  287 ALA C CA  
5990 C C   . ALA C 31 ? 0.1330 0.2321 0.0766 0.0185  0.0085  0.0368  287 ALA C C   
5991 O O   . ALA C 31 ? 0.1236 0.2239 0.0670 0.0118  0.0097  0.0288  287 ALA C O   
5992 C CB  . ALA C 31 ? 0.2106 0.2712 0.1149 0.0590  0.0111  0.0357  287 ALA C CB  
5993 N N   . PHE C 32 ? 0.1313 0.2422 0.0731 0.0118  0.0091  0.0406  288 PHE C N   
5994 C CA  . PHE C 32 ? 0.1602 0.2220 0.0722 -0.0121 -0.0040 0.0311  288 PHE C CA  
5995 C C   . PHE C 32 ? 0.1336 0.2129 0.0728 0.0043  -0.0110 0.0379  288 PHE C C   
5996 O O   . PHE C 32 ? 0.1335 0.2644 0.0927 0.0023  -0.0120 0.0430  288 PHE C O   
5997 C CB  . PHE C 32 ? 0.1784 0.2222 0.0882 0.0086  0.0116  0.0294  288 PHE C CB  
5998 C CG  . PHE C 32 ? 0.1777 0.2137 0.0864 -0.0073 0.0045  0.0297  288 PHE C CG  
5999 C CD1 . PHE C 32 ? 0.1652 0.2196 0.1034 0.0140  0.0021  0.0191  288 PHE C CD1 
6000 C CD2 . PHE C 32 ? 0.2065 0.2598 0.1005 0.0022  -0.0144 0.0101  288 PHE C CD2 
6001 C CE1 . PHE C 32 ? 0.1994 0.2222 0.1093 0.0147  0.0133  0.0283  288 PHE C CE1 
6002 C CE2 . PHE C 32 ? 0.2674 0.2826 0.1121 0.0091  -0.0207 0.0123  288 PHE C CE2 
6003 C CZ  . PHE C 32 ? 0.2630 0.2396 0.1034 0.0413  0.0136  0.0207  288 PHE C CZ  
6004 N N   . ASN C 33 ? 0.1433 0.2045 0.0630 -0.0124 -0.0154 0.0333  289 ASN C N   
6005 C CA  . ASN C 33 ? 0.1365 0.2097 0.0714 -0.0002 -0.0156 0.0373  289 ASN C CA  
6006 C C   . ASN C 33 ? 0.1395 0.1921 0.0597 0.0036  -0.0130 0.0304  289 ASN C C   
6007 O O   . ASN C 33 ? 0.1420 0.2120 0.0617 -0.0131 -0.0164 0.0117  289 ASN C O   
6008 C CB  . ASN C 33 ? 0.1563 0.2314 0.0906 0.0020  -0.0138 0.0288  289 ASN C CB  
6009 C CG  . ASN C 33 ? 0.1899 0.2105 0.1011 0.0125  -0.0058 0.0232  289 ASN C CG  
6010 O OD1 . ASN C 33 ? 0.2053 0.2182 0.1103 0.0043  -0.0193 0.0166  289 ASN C OD1 
6011 N ND2 . ASN C 33 ? 0.2239 0.2045 0.1168 0.0042  0.0037  0.0346  289 ASN C ND2 
6012 N N   . LEU C 34 ? 0.1514 0.2025 0.0603 -0.0137 -0.0188 0.0227  290 LEU C N   
6013 C CA  . LEU C 34 ? 0.1589 0.1981 0.0531 -0.0068 -0.0106 0.0166  290 LEU C CA  
6014 C C   . LEU C 34 ? 0.1605 0.1894 0.0537 0.0014  -0.0237 0.0121  290 LEU C C   
6015 O O   . LEU C 34 ? 0.1691 0.2061 0.0788 -0.0075 -0.0287 0.0185  290 LEU C O   
6016 C CB  . LEU C 34 ? 0.1698 0.1863 0.0800 -0.0002 -0.0245 0.0157  290 LEU C CB  
6017 C CG  . LEU C 34 ? 0.1880 0.1816 0.0918 -0.0031 -0.0316 0.0103  290 LEU C CG  
6018 C CD1 . LEU C 34 ? 0.1897 0.1910 0.0924 -0.0070 -0.0191 0.0055  290 LEU C CD1 
6019 C CD2 . LEU C 34 ? 0.2022 0.2177 0.1180 0.0019  -0.0303 -0.0120 290 LEU C CD2 
6020 N N   . VAL C 35 ? 0.1679 0.1849 0.0533 -0.0032 -0.0211 0.0184  291 VAL C N   
6021 C CA  . VAL C 35 ? 0.1836 0.1798 0.0509 0.0044  -0.0166 0.0167  291 VAL C CA  
6022 C C   . VAL C 35 ? 0.1953 0.1680 0.0569 0.0007  -0.0156 0.0265  291 VAL C C   
6023 O O   . VAL C 35 ? 0.2171 0.1751 0.0600 0.0132  -0.0226 0.0094  291 VAL C O   
6024 C CB  . VAL C 35 ? 0.1890 0.1895 0.0780 -0.0068 -0.0169 0.0072  291 VAL C CB  
6025 C CG1 . VAL C 35 ? 0.2057 0.2030 0.0984 -0.0071 0.0082  0.0064  291 VAL C CG1 
6026 C CG2 . VAL C 35 ? 0.1971 0.2017 0.0705 0.0001  -0.0144 -0.0114 291 VAL C CG2 
6027 N N   . LYS C 36 ? 0.2112 0.1762 0.0615 -0.0055 -0.0280 0.0166  292 LYS C N   
6028 C CA  . LYS C 36 ? 0.2336 0.1917 0.0738 -0.0172 -0.0359 0.0254  292 LYS C CA  
6029 C C   . LYS C 36 ? 0.1985 0.1875 0.0683 -0.0061 -0.0377 0.0192  292 LYS C C   
6030 O O   . LYS C 36 ? 0.2273 0.1928 0.0702 -0.0021 -0.0386 0.0169  292 LYS C O   
6031 C CB  . LYS C 36 ? 0.2751 0.2446 0.1043 -0.0488 -0.0500 0.0480  292 LYS C CB  
6032 C CG  . LYS C 36 ? 0.3165 0.3452 0.1369 -0.0796 -0.0764 0.0394  292 LYS C CG  
6033 C CD  . LYS C 36 ? 0.3669 0.3420 0.1863 -0.0805 -0.0478 0.0566  292 LYS C CD  
6034 C CE  . LYS C 36 ? 0.3671 0.3235 0.1974 -0.0982 -0.0651 0.0579  292 LYS C CE  
6035 N NZ  . LYS C 36 ? 0.3132 0.3085 0.2014 -0.0998 -0.0880 0.0613  292 LYS C NZ  
6036 N N   . ASP C 37 ? 0.1930 0.1879 0.0633 0.0002  -0.0316 0.0271  293 ASP C N   
6037 C CA  . ASP C 37 ? 0.1532 0.1825 0.0712 -0.0065 -0.0233 0.0284  293 ASP C CA  
6038 C C   . ASP C 37 ? 0.1500 0.1793 0.0695 -0.0108 -0.0256 0.0339  293 ASP C C   
6039 O O   . ASP C 37 ? 0.1624 0.1985 0.0982 -0.0333 -0.0371 0.0341  293 ASP C O   
6040 C CB  . ASP C 37 ? 0.1596 0.2223 0.0893 -0.0082 -0.0276 0.0355  293 ASP C CB  
6041 C CG  . ASP C 37 ? 0.1329 0.2149 0.1181 -0.0246 -0.0292 0.0212  293 ASP C CG  
6042 O OD1 . ASP C 37 ? 0.1233 0.2189 0.1011 -0.0109 -0.0322 0.0100  293 ASP C OD1 
6043 O OD2 . ASP C 37 ? 0.1265 0.2413 0.2132 -0.0071 -0.0003 0.0341  293 ASP C OD2 
6044 N N   . SER C 38 ? 0.1231 0.1803 0.0619 -0.0146 -0.0164 0.0319  294 SER C N   
6045 C CA  . SER C 38 ? 0.1191 0.2198 0.0772 -0.0176 0.0100  0.0232  294 SER C CA  
6046 C C   . SER C 38 ? 0.1102 0.2362 0.0965 0.0026  -0.0067 0.0193  294 SER C C   
6047 O O   . SER C 38 ? 0.1145 0.3365 0.1184 -0.0211 -0.0001 0.0540  294 SER C O   
6048 C CB  . SER C 38 ? 0.1506 0.2129 0.0865 -0.0021 0.0111  0.0197  294 SER C CB  
6049 O OG  . SER C 38 ? 0.1661 0.2255 0.1001 -0.0151 0.0141  0.0245  294 SER C OG  
6050 N N   . ALA C 39 ? 0.1130 0.2122 0.0778 -0.0044 -0.0158 0.0261  295 ALA C N   
6051 C CA  . ALA C 39 ? 0.1442 0.2179 0.0770 -0.0010 -0.0267 0.0283  295 ALA C CA  
6052 C C   . ALA C 39 ? 0.1704 0.2390 0.0934 -0.0222 -0.0533 0.0295  295 ALA C C   
6053 O O   . ALA C 39 ? 0.1987 0.2858 0.1700 -0.0108 -0.1085 -0.0005 295 ALA C O   
6054 C CB  . ALA C 39 ? 0.1693 0.2196 0.0712 -0.0115 -0.0253 0.0366  295 ALA C CB  
6055 N N   . THR C 40 ? 0.1781 0.2181 0.0942 -0.0126 -0.0588 0.0254  296 THR C N   
6056 C CA  . THR C 40 ? 0.2130 0.2139 0.0902 -0.0199 -0.0604 0.0122  296 THR C CA  
6057 C C   . THR C 40 ? 0.1925 0.2376 0.1087 -0.0371 -0.0505 0.0128  296 THR C C   
6058 O O   . THR C 40 ? 0.2495 0.2350 0.1194 -0.0555 -0.0657 0.0017  296 THR C O   
6059 C CB  . THR C 40 ? 0.2225 0.2162 0.1069 -0.0111 -0.0306 0.0165  296 THR C CB  
6060 O OG1 . THR C 40 ? 0.1916 0.2278 0.1164 0.0041  -0.0380 0.0185  296 THR C OG1 
6061 C CG2 . THR C 40 ? 0.2595 0.2524 0.1315 0.0169  -0.0044 0.0201  296 THR C CG2 
6062 N N   . GLY C 41 ? 0.1987 0.2522 0.1044 -0.0657 -0.0467 0.0335  297 GLY C N   
6063 C CA  . GLY C 41 ? 0.2740 0.2549 0.1256 -0.0844 -0.0343 0.0243  297 GLY C CA  
6064 C C   . GLY C 41 ? 0.3331 0.2255 0.1249 -0.0862 -0.0570 0.0362  297 GLY C C   
6065 O O   . GLY C 41 ? 0.4302 0.2509 0.1409 -0.1094 -0.0371 0.0484  297 GLY C O   
6066 N N   . LEU C 42 ? 0.3193 0.2023 0.1138 -0.0518 -0.0731 0.0187  298 LEU C N   
6067 C CA  . LEU C 42 ? 0.3442 0.2099 0.1088 -0.0038 -0.0674 0.0070  298 LEU C CA  
6068 C C   . LEU C 42 ? 0.3256 0.1819 0.0982 0.0115  -0.0539 0.0099  298 LEU C C   
6069 O O   . LEU C 42 ? 0.3367 0.1778 0.1063 0.0191  -0.0616 0.0104  298 LEU C O   
6070 C CB  . LEU C 42 ? 0.3958 0.2641 0.1188 0.0155  -0.0657 -0.0150 298 LEU C CB  
6071 C CG  . LEU C 42 ? 0.4775 0.2947 0.1369 -0.0165 -0.0657 -0.0156 298 LEU C CG  
6072 C CD1 . LEU C 42 ? 0.4968 0.3738 0.1352 -0.0215 -0.0392 -0.0334 298 LEU C CD1 
6073 C CD2 . LEU C 42 ? 0.5068 0.3264 0.1581 -0.0779 -0.0790 -0.0098 298 LEU C CD2 
6074 N N   . SER C 43 ? 0.3130 0.1773 0.0951 0.0072  -0.0551 0.0045  299 SER C N   
6075 C CA  . SER C 43 ? 0.2588 0.1760 0.0822 0.0146  -0.0507 -0.0046 299 SER C CA  
6076 C C   . SER C 43 ? 0.2619 0.1768 0.0689 0.0130  -0.0152 0.0117  299 SER C C   
6077 O O   . SER C 43 ? 0.3114 0.2001 0.0817 0.0125  0.0034  -0.0036 299 SER C O   
6078 C CB  . SER C 43 ? 0.3003 0.1882 0.0898 0.0072  -0.0454 0.0136  299 SER C CB  
6079 O OG  . SER C 43 ? 0.2817 0.1665 0.0956 0.0041  -0.0566 0.0219  299 SER C OG  
6080 N N   . LYS C 44 ? 0.2220 0.1729 0.0615 0.0329  -0.0071 0.0115  300 LYS C N   
6081 C CA  . LYS C 44 ? 0.2022 0.1988 0.0692 0.0283  0.0085  0.0078  300 LYS C CA  
6082 C C   . LYS C 44 ? 0.2233 0.1974 0.0712 0.0162  0.0031  0.0037  300 LYS C C   
6083 O O   . LYS C 44 ? 0.2427 0.2137 0.0985 0.0250  0.0135  0.0158  300 LYS C O   
6084 C CB  . LYS C 44 ? 0.1607 0.2016 0.0907 0.0006  0.0069  0.0227  300 LYS C CB  
6085 C CG  . LYS C 44 ? 0.1420 0.1988 0.1174 -0.0019 0.0181  0.0337  300 LYS C CG  
6086 C CD  . LYS C 44 ? 0.0968 0.2102 0.1272 0.0127  0.0168  0.0352  300 LYS C CD  
6087 C CE  . LYS C 44 ? 0.1036 0.1898 0.1238 0.0046  0.0029  0.0382  300 LYS C CE  
6088 N NZ  . LYS C 44 ? 0.1086 0.1923 0.1439 0.0138  -0.0166 0.0183  300 LYS C NZ  
6089 N N   . GLY C 45 ? 0.2465 0.1721 0.0718 0.0110  -0.0144 0.0067  301 GLY C N   
6090 C CA  . GLY C 45 ? 0.2363 0.1769 0.0715 0.0294  -0.0303 0.0140  301 GLY C CA  
6091 C C   . GLY C 45 ? 0.2039 0.1814 0.0684 0.0019  -0.0142 0.0067  301 GLY C C   
6092 O O   . GLY C 45 ? 0.1994 0.1789 0.0910 0.0046  -0.0270 0.0055  301 GLY C O   
6093 N N   . TYR C 46 ? 0.1859 0.1692 0.0548 0.0167  -0.0075 0.0107  302 TYR C N   
6094 C CA  . TYR C 46 ? 0.1787 0.1681 0.0543 -0.0122 -0.0071 0.0111  302 TYR C CA  
6095 C C   . TYR C 46 ? 0.1582 0.1722 0.0643 -0.0049 -0.0150 0.0103  302 TYR C C   
6096 O O   . TYR C 46 ? 0.1574 0.2031 0.0795 -0.0166 -0.0295 0.0275  302 TYR C O   
6097 C CB  . TYR C 46 ? 0.1837 0.1818 0.0656 0.0017  -0.0116 -0.0033 302 TYR C CB  
6098 C CG  . TYR C 46 ? 0.1921 0.1624 0.0798 -0.0133 0.0151  0.0087  302 TYR C CG  
6099 C CD1 . TYR C 46 ? 0.1611 0.1960 0.1078 -0.0147 -0.0021 0.0104  302 TYR C CD1 
6100 C CD2 . TYR C 46 ? 0.1855 0.2374 0.0854 -0.0187 -0.0018 0.0409  302 TYR C CD2 
6101 C CE1 . TYR C 46 ? 0.1762 0.2080 0.1301 -0.0257 0.0005  0.0081  302 TYR C CE1 
6102 C CE2 . TYR C 46 ? 0.1996 0.2353 0.0949 -0.0328 -0.0068 0.0542  302 TYR C CE2 
6103 C CZ  . TYR C 46 ? 0.1888 0.2210 0.1250 -0.0153 0.0164  0.0151  302 TYR C CZ  
6104 O OH  . TYR C 46 ? 0.2019 0.2891 0.1579 -0.0701 0.0209  0.0144  302 TYR C OH  
6105 N N   . ALA C 47 ? 0.1489 0.1830 0.0538 -0.0037 -0.0054 0.0030  303 ALA C N   
6106 C CA  . ALA C 47 ? 0.1494 0.1863 0.0660 -0.0115 -0.0122 0.0017  303 ALA C CA  
6107 C C   . ALA C 47 ? 0.1345 0.1760 0.0633 0.0006  0.0002  0.0150  303 ALA C C   
6108 O O   . ALA C 47 ? 0.1331 0.2159 0.0738 -0.0126 -0.0068 -0.0126 303 ALA C O   
6109 C CB  . ALA C 47 ? 0.1537 0.1959 0.0850 -0.0159 -0.0052 0.0026  303 ALA C CB  
6110 N N   . PHE C 48 ? 0.1368 0.1951 0.0518 -0.0044 -0.0037 0.0182  304 PHE C N   
6111 C CA  . PHE C 48 ? 0.1376 0.1887 0.0487 -0.0050 -0.0044 0.0117  304 PHE C CA  
6112 C C   . PHE C 48 ? 0.1462 0.2055 0.0564 -0.0212 -0.0035 0.0168  304 PHE C C   
6113 O O   . PHE C 48 ? 0.1442 0.2526 0.0768 -0.0310 -0.0132 0.0402  304 PHE C O   
6114 C CB  . PHE C 48 ? 0.1596 0.2066 0.0560 0.0005  -0.0009 -0.0007 304 PHE C CB  
6115 C CG  . PHE C 48 ? 0.1668 0.1805 0.0533 -0.0073 0.0052  0.0155  304 PHE C CG  
6116 C CD1 . PHE C 48 ? 0.1992 0.1894 0.0597 0.0040  -0.0142 0.0235  304 PHE C CD1 
6117 C CD2 . PHE C 48 ? 0.1993 0.2083 0.0625 -0.0057 0.0030  0.0126  304 PHE C CD2 
6118 C CE1 . PHE C 48 ? 0.2178 0.1978 0.0635 0.0021  -0.0088 0.0313  304 PHE C CE1 
6119 C CE2 . PHE C 48 ? 0.2184 0.2222 0.0860 -0.0385 -0.0131 0.0109  304 PHE C CE2 
6120 C CZ  . PHE C 48 ? 0.2314 0.1989 0.0931 -0.0178 -0.0112 0.0293  304 PHE C CZ  
6121 N N   . CYS C 49 ? 0.1423 0.1955 0.0537 -0.0133 -0.0021 0.0216  305 CYS C N   
6122 C CA  . CYS C 49 ? 0.1400 0.2096 0.0570 0.0034  -0.0005 0.0137  305 CYS C CA  
6123 C C   . CYS C 49 ? 0.1483 0.1924 0.0573 -0.0052 0.0021  0.0087  305 CYS C C   
6124 O O   . CYS C 49 ? 0.1543 0.2237 0.0586 -0.0177 0.0119  0.0019  305 CYS C O   
6125 C CB  . CYS C 49 ? 0.1700 0.2059 0.0790 -0.0008 -0.0061 -0.0038 305 CYS C CB  
6126 S SG  . CYS C 49 ? 0.1754 0.2329 0.1036 0.0185  -0.0087 0.0033  305 CYS C SG  
6127 N N   . GLU C 50 ? 0.1301 0.2004 0.0537 -0.0145 0.0045  0.0171  306 GLU C N   
6128 C CA  . GLU C 50 ? 0.1414 0.1952 0.0530 -0.0119 0.0041  0.0091  306 GLU C CA  
6129 C C   . GLU C 50 ? 0.1307 0.1924 0.0503 -0.0057 0.0073  0.0125  306 GLU C C   
6130 O O   . GLU C 50 ? 0.1164 0.2236 0.0865 -0.0122 -0.0126 0.0404  306 GLU C O   
6131 C CB  . GLU C 50 ? 0.1924 0.1996 0.0877 0.0189  0.0123  0.0016  306 GLU C CB  
6132 C CG  . GLU C 50 ? 0.2816 0.1855 0.0990 0.0199  0.0174  -0.0057 306 GLU C CG  
6133 C CD  . GLU C 50 ? 0.4313 0.2619 0.1443 0.0450  0.0306  -0.0135 306 GLU C CD  
6134 O OE1 . GLU C 50 ? 0.4292 0.3210 0.1927 0.1001  0.0074  -0.0268 306 GLU C OE1 
6135 O OE2 . GLU C 50 ? 0.5421 0.3285 0.1678 0.0760  0.0493  -0.0056 306 GLU C OE2 
6136 N N   . TYR C 51 ? 0.1071 0.1875 0.0492 0.0024  0.0111  0.0056  307 TYR C N   
6137 C CA  . TYR C 51 ? 0.1028 0.1787 0.0459 -0.0007 0.0082  -0.0008 307 TYR C CA  
6138 C C   . TYR C 51 ? 0.1014 0.1893 0.0500 0.0088  0.0114  -0.0009 307 TYR C C   
6139 O O   . TYR C 51 ? 0.1462 0.1908 0.0598 -0.0096 0.0287  -0.0057 307 TYR C O   
6140 C CB  . TYR C 51 ? 0.0963 0.1936 0.0504 0.0008  0.0081  0.0086  307 TYR C CB  
6141 C CG  . TYR C 51 ? 0.0921 0.1886 0.0486 -0.0015 0.0020  0.0122  307 TYR C CG  
6142 C CD1 . TYR C 51 ? 0.0900 0.1865 0.0746 -0.0077 0.0160  0.0207  307 TYR C CD1 
6143 C CD2 . TYR C 51 ? 0.0936 0.1878 0.0525 -0.0106 0.0101  0.0086  307 TYR C CD2 
6144 C CE1 . TYR C 51 ? 0.1061 0.1697 0.0668 -0.0040 0.0035  0.0026  307 TYR C CE1 
6145 C CE2 . TYR C 51 ? 0.0872 0.1919 0.0514 -0.0124 0.0015  0.0179  307 TYR C CE2 
6146 C CZ  . TYR C 51 ? 0.0816 0.1864 0.0515 -0.0067 0.0057  0.0030  307 TYR C CZ  
6147 O OH  . TYR C 51 ? 0.1102 0.1876 0.0592 -0.0008 0.0090  -0.0103 307 TYR C OH  
6148 N N   . VAL C 52 ? 0.0955 0.1851 0.0512 0.0006  0.0059  0.0052  308 VAL C N   
6149 C CA  . VAL C 52 ? 0.0996 0.1938 0.0545 0.0068  0.0170  0.0065  308 VAL C CA  
6150 C C   . VAL C 52 ? 0.0928 0.2089 0.0546 0.0007  0.0055  0.0124  308 VAL C C   
6151 O O   . VAL C 52 ? 0.1262 0.2328 0.0619 0.0300  0.0063  -0.0099 308 VAL C O   
6152 C CB  . VAL C 52 ? 0.0905 0.2066 0.0750 0.0138  0.0170  0.0157  308 VAL C CB  
6153 C CG1 . VAL C 52 ? 0.1184 0.2261 0.0901 0.0051  0.0332  0.0198  308 VAL C CG1 
6154 C CG2 . VAL C 52 ? 0.1147 0.2421 0.0805 0.0122  0.0114  0.0065  308 VAL C CG2 
6155 N N   . ASP C 53 ? 0.0819 0.2231 0.0584 0.0093  0.0064  0.0124  309 ASP C N   
6156 C CA  . ASP C 53 ? 0.0952 0.2352 0.0677 0.0221  0.0103  0.0197  309 ASP C CA  
6157 C C   . ASP C 53 ? 0.0808 0.2182 0.0562 0.0158  0.0030  -0.0085 309 ASP C C   
6158 O O   . ASP C 53 ? 0.0909 0.2245 0.0579 0.0032  0.0073  -0.0046 309 ASP C O   
6159 C CB  . ASP C 53 ? 0.0991 0.2567 0.0916 0.0085  0.0153  0.0310  309 ASP C CB  
6160 C CG  . ASP C 53 ? 0.1449 0.2809 0.1056 -0.0018 0.0053  0.0005  309 ASP C CG  
6161 O OD1 . ASP C 53 ? 0.1506 0.3075 0.1352 -0.0280 0.0358  -0.0036 309 ASP C OD1 
6162 O OD2 . ASP C 53 ? 0.1601 0.2583 0.1084 -0.0083 0.0329  0.0105  309 ASP C OD2 
6163 N N   . ILE C 54 ? 0.0951 0.2459 0.0733 0.0173  0.0069  -0.0266 310 ILE C N   
6164 C CA  . ILE C 54 ? 0.1024 0.2296 0.1030 0.0184  -0.0135 -0.0473 310 ILE C CA  
6165 C C   . ILE C 54 ? 0.0992 0.2511 0.0738 0.0294  -0.0070 -0.0287 310 ILE C C   
6166 O O   . ILE C 54 ? 0.0894 0.2497 0.0784 0.0182  0.0026  -0.0297 310 ILE C O   
6167 C CB  . ILE C 54 ? 0.1023 0.2776 0.1631 0.0165  -0.0055 -0.0753 310 ILE C CB  
6168 C CG1 . ILE C 54 ? 0.1661 0.2652 0.1995 -0.0284 0.0058  -0.0985 310 ILE C CG1 
6169 C CG2 . ILE C 54 ? 0.1374 0.3052 0.1523 0.0286  -0.0268 -0.0813 310 ILE C CG2 
6170 C CD1 . ILE C 54 ? 0.1906 0.3280 0.2185 -0.0407 0.0289  -0.0759 310 ILE C CD1 
6171 N N   . ASN C 55 ? 0.1135 0.2355 0.0632 0.0206  -0.0043 -0.0218 311 ASN C N   
6172 C CA  . ASN C 55 ? 0.1185 0.2335 0.0632 0.0409  -0.0062 -0.0136 311 ASN C CA  
6173 C C   . ASN C 55 ? 0.1180 0.2244 0.0633 0.0232  -0.0016 -0.0098 311 ASN C C   
6174 O O   . ASN C 55 ? 0.1451 0.2149 0.0746 0.0368  -0.0288 -0.0216 311 ASN C O   
6175 C CB  . ASN C 55 ? 0.1764 0.2712 0.0740 0.0394  -0.0099 0.0135  311 ASN C CB  
6176 C CG  . ASN C 55 ? 0.1607 0.3115 0.0862 0.0336  0.0144  0.0306  311 ASN C CG  
6177 O OD1 . ASN C 55 ? 0.1875 0.3381 0.0860 -0.0041 -0.0097 0.0083  311 ASN C OD1 
6178 N ND2 . ASN C 55 ? 0.2365 0.3735 0.1126 -0.0155 0.0122  0.0252  311 ASN C ND2 
6179 N N   . VAL C 56 ? 0.0881 0.2262 0.0701 0.0172  0.0052  0.0030  312 VAL C N   
6180 C CA  . VAL C 56 ? 0.1044 0.1968 0.0645 0.0217  0.0008  -0.0063 312 VAL C CA  
6181 C C   . VAL C 56 ? 0.0932 0.2013 0.0704 0.0009  -0.0100 -0.0154 312 VAL C C   
6182 O O   . VAL C 56 ? 0.1029 0.2085 0.0601 0.0089  0.0131  -0.0215 312 VAL C O   
6183 C CB  . VAL C 56 ? 0.0963 0.2010 0.0763 0.0045  -0.0017 0.0086  312 VAL C CB  
6184 C CG1 . VAL C 56 ? 0.1021 0.2181 0.0883 -0.0121 -0.0059 0.0213  312 VAL C CG1 
6185 C CG2 . VAL C 56 ? 0.1227 0.2096 0.1004 0.0055  0.0125  0.0288  312 VAL C CG2 
6186 N N   . THR C 57 ? 0.0900 0.2043 0.0594 0.0038  0.0009  -0.0165 313 THR C N   
6187 C CA  . THR C 57 ? 0.0894 0.1876 0.0651 0.0017  -0.0082 -0.0269 313 THR C CA  
6188 C C   . THR C 57 ? 0.0939 0.1845 0.0507 -0.0043 0.0019  -0.0222 313 THR C C   
6189 O O   . THR C 57 ? 0.0957 0.1933 0.0603 0.0038  0.0018  -0.0165 313 THR C O   
6190 C CB  . THR C 57 ? 0.0929 0.1887 0.0957 0.0211  -0.0194 -0.0184 313 THR C CB  
6191 O OG1 . THR C 57 ? 0.1006 0.1927 0.1195 0.0194  -0.0081 -0.0272 313 THR C OG1 
6192 C CG2 . THR C 57 ? 0.1249 0.1841 0.1146 0.0131  -0.0052 -0.0173 313 THR C CG2 
6193 N N   . ASP C 58 ? 0.0841 0.2028 0.0561 0.0093  -0.0027 -0.0153 314 ASP C N   
6194 C CA  . ASP C 58 ? 0.0949 0.2025 0.0629 0.0011  -0.0030 -0.0264 314 ASP C CA  
6195 C C   . ASP C 58 ? 0.0664 0.2102 0.0552 0.0093  -0.0051 -0.0114 314 ASP C C   
6196 O O   . ASP C 58 ? 0.0834 0.2048 0.0802 0.0094  -0.0021 -0.0168 314 ASP C O   
6197 C CB  . ASP C 58 ? 0.1090 0.2248 0.0788 0.0132  -0.0153 -0.0316 314 ASP C CB  
6198 C CG  . ASP C 58 ? 0.0969 0.3082 0.1079 0.0142  -0.0211 -0.0409 314 ASP C CG  
6199 O OD1 . ASP C 58 ? 0.1748 0.2642 0.1667 0.0005  -0.0205 -0.0545 314 ASP C OD1 
6200 O OD2 . ASP C 58 ? 0.1242 0.4167 0.1342 0.0430  -0.0162 -0.0773 314 ASP C OD2 
6201 N N   . GLN C 59 ? 0.0769 0.1996 0.0509 0.0126  -0.0025 -0.0078 315 GLN C N   
6202 C CA  . GLN C 59 ? 0.0912 0.2023 0.0672 0.0043  0.0037  0.0023  315 GLN C CA  
6203 C C   . GLN C 59 ? 0.0892 0.1798 0.0567 0.0054  0.0004  -0.0077 315 GLN C C   
6204 O O   . GLN C 59 ? 0.0985 0.1910 0.0664 0.0229  0.0090  -0.0121 315 GLN C O   
6205 C CB  . GLN C 59 ? 0.1746 0.2177 0.0780 -0.0323 0.0230  0.0383  315 GLN C CB  
6206 C CG  . GLN C 59 ? 0.2673 0.2539 0.1073 -0.0097 0.0015  0.0788  315 GLN C CG  
6207 C CD  . GLN C 59 ? 0.3665 0.3271 0.1472 -0.0676 0.0211  0.0786  315 GLN C CD  
6208 O OE1 . GLN C 59 ? 0.4245 0.3703 0.1856 -0.1208 0.0549  0.0607  315 GLN C OE1 
6209 N NE2 . GLN C 59 ? 0.3505 0.3719 0.1440 -0.0016 0.0527  0.0906  315 GLN C NE2 
6210 N N   . ALA C 60 ? 0.0854 0.1793 0.0521 0.0163  0.0091  -0.0116 316 ALA C N   
6211 C CA  . ALA C 60 ? 0.0993 0.1686 0.0544 0.0052  -0.0071 -0.0159 316 ALA C CA  
6212 C C   . ALA C 60 ? 0.0885 0.1765 0.0500 0.0069  -0.0037 -0.0149 316 ALA C C   
6213 O O   . ALA C 60 ? 0.1062 0.2009 0.0547 0.0070  0.0016  -0.0225 316 ALA C O   
6214 C CB  . ALA C 60 ? 0.0950 0.1919 0.0665 0.0037  -0.0060 -0.0104 316 ALA C CB  
6215 N N   . ILE C 61 ? 0.0970 0.1782 0.0529 0.0169  -0.0025 -0.0281 317 ILE C N   
6216 C CA  . ILE C 61 ? 0.1177 0.2069 0.0635 0.0050  -0.0072 -0.0214 317 ILE C CA  
6217 C C   . ILE C 61 ? 0.0828 0.2029 0.0638 -0.0106 0.0004  -0.0389 317 ILE C C   
6218 O O   . ILE C 61 ? 0.0819 0.2135 0.0763 -0.0104 0.0055  -0.0529 317 ILE C O   
6219 C CB  . ILE C 61 ? 0.1675 0.2196 0.1053 -0.0012 -0.0042 0.0178  317 ILE C CB  
6220 C CG1 . ILE C 61 ? 0.2619 0.2446 0.1219 -0.0426 0.0538  -0.0247 317 ILE C CG1 
6221 C CG2 . ILE C 61 ? 0.2150 0.2294 0.1307 -0.0138 -0.0468 0.0480  317 ILE C CG2 
6222 C CD1 . ILE C 61 ? 0.3050 0.2652 0.1484 -0.0433 0.0450  -0.0651 317 ILE C CD1 
6223 N N   . ALA C 62 ? 0.1019 0.2098 0.0536 0.0094  -0.0028 -0.0101 318 ALA C N   
6224 C CA  . ALA C 62 ? 0.0914 0.2282 0.0658 0.0168  -0.0005 -0.0330 318 ALA C CA  
6225 C C   . ALA C 62 ? 0.0997 0.2218 0.0575 0.0106  0.0009  -0.0154 318 ALA C C   
6226 O O   . ALA C 62 ? 0.0973 0.2601 0.0744 0.0144  0.0067  -0.0314 318 ALA C O   
6227 C CB  . ALA C 62 ? 0.1115 0.2390 0.0748 0.0323  -0.0166 -0.0388 318 ALA C CB  
6228 N N   . GLY C 63 ? 0.1073 0.1992 0.0534 0.0178  -0.0032 -0.0181 319 GLY C N   
6229 C CA  . GLY C 63 ? 0.1221 0.2021 0.0518 0.0186  -0.0033 -0.0034 319 GLY C CA  
6230 C C   . GLY C 63 ? 0.1090 0.1976 0.0579 0.0032  -0.0036 -0.0185 319 GLY C C   
6231 O O   . GLY C 63 ? 0.1269 0.1945 0.0578 0.0139  -0.0070 -0.0284 319 GLY C O   
6232 N N   . LEU C 64 ? 0.1245 0.1771 0.0458 0.0142  -0.0014 -0.0082 320 LEU C N   
6233 C CA  . LEU C 64 ? 0.1104 0.1779 0.0489 0.0022  -0.0069 -0.0134 320 LEU C CA  
6234 C C   . LEU C 64 ? 0.1135 0.1840 0.0501 0.0040  0.0009  -0.0209 320 LEU C C   
6235 O O   . LEU C 64 ? 0.1295 0.2006 0.0516 0.0057  -0.0012 -0.0124 320 LEU C O   
6236 C CB  . LEU C 64 ? 0.1298 0.1697 0.0524 -0.0046 -0.0077 -0.0036 320 LEU C CB  
6237 C CG  . LEU C 64 ? 0.1233 0.1861 0.0763 -0.0152 -0.0205 -0.0050 320 LEU C CG  
6238 C CD1 . LEU C 64 ? 0.1303 0.2131 0.0913 0.0085  -0.0073 -0.0086 320 LEU C CD1 
6239 C CD2 . LEU C 64 ? 0.1378 0.2057 0.0803 -0.0045 -0.0149 -0.0029 320 LEU C CD2 
6240 N N   . ASN C 65 ? 0.1279 0.1943 0.0536 -0.0142 0.0127  -0.0172 321 ASN C N   
6241 C CA  . ASN C 65 ? 0.1179 0.2114 0.0665 -0.0012 0.0053  -0.0226 321 ASN C CA  
6242 C C   . ASN C 65 ? 0.1178 0.2128 0.0707 0.0000  0.0116  -0.0046 321 ASN C C   
6243 O O   . ASN C 65 ? 0.1496 0.2287 0.0861 0.0176  0.0035  -0.0014 321 ASN C O   
6244 C CB  . ASN C 65 ? 0.1310 0.2304 0.0751 0.0034  -0.0021 -0.0199 321 ASN C CB  
6245 C CG  . ASN C 65 ? 0.1292 0.2410 0.1115 -0.0152 -0.0049 -0.0110 321 ASN C CG  
6246 O OD1 . ASN C 65 ? 0.1226 0.2588 0.1056 -0.0260 0.0113  0.0014  321 ASN C OD1 
6247 N ND2 . ASN C 65 ? 0.1443 0.2777 0.1706 -0.0280 -0.0310 0.0034  321 ASN C ND2 
6248 N N   . GLY C 66 ? 0.1270 0.2136 0.0756 0.0130  0.0115  -0.0076 322 GLY C N   
6249 C CA  . GLY C 66 ? 0.1409 0.2436 0.0939 0.0166  0.0256  -0.0095 322 GLY C CA  
6250 C C   . GLY C 66 ? 0.1297 0.2252 0.0959 0.0003  0.0281  -0.0267 322 GLY C C   
6251 O O   . GLY C 66 ? 0.1792 0.2451 0.1450 0.0364  0.0497  -0.0337 322 GLY C O   
6252 N N   . MET C 67 ? 0.1467 0.2134 0.0725 0.0019  0.0043  -0.0256 323 MET C N   
6253 C CA  . MET C 67 ? 0.1493 0.1930 0.0824 0.0243  0.0210  -0.0016 323 MET C CA  
6254 C C   . MET C 67 ? 0.1799 0.2062 0.0735 0.0077  0.0027  -0.0298 323 MET C C   
6255 O O   . MET C 67 ? 0.2235 0.1882 0.0791 0.0258  -0.0051 -0.0055 323 MET C O   
6256 C CB  . MET C 67 ? 0.1751 0.2021 0.0932 0.0108  0.0268  -0.0042 323 MET C CB  
6257 C CG  . MET C 67 ? 0.1842 0.1917 0.0892 -0.0020 -0.0142 -0.0327 323 MET C CG  
6258 S SD  . MET C 67 ? 0.1464 0.1805 0.1167 0.0069  -0.0021 -0.0084 323 MET C SD  
6259 C CE  . MET C 67 ? 0.1545 0.1925 0.1261 -0.0211 -0.0190 -0.0244 323 MET C CE  
6260 N N   . GLN C 68 ? 0.2385 0.2042 0.0775 0.0508  -0.0048 -0.0323 324 GLN C N   
6261 C CA  . GLN C 68 ? 0.2395 0.2177 0.0876 0.0458  0.0141  -0.0378 324 GLN C CA  
6262 C C   . GLN C 68 ? 0.2470 0.1922 0.0982 0.0240  0.0113  -0.0044 324 GLN C C   
6263 O O   . GLN C 68 ? 0.2498 0.1780 0.1217 0.0250  0.0237  0.0067  324 GLN C O   
6264 C CB  . GLN C 68 ? 0.2551 0.2541 0.1114 0.0509  0.0180  -0.0606 324 GLN C CB  
6265 C CG  . GLN C 68 ? 0.2774 0.2603 0.1484 0.0548  0.0154  -0.0769 324 GLN C CG  
6266 C CD  . GLN C 68 ? 0.3025 0.2631 0.1796 0.0442  0.0248  -0.0878 324 GLN C CD  
6267 O OE1 . GLN C 68 ? 0.3274 0.3393 0.1952 -0.0203 0.0191  -0.0581 324 GLN C OE1 
6268 N NE2 . GLN C 68 ? 0.2985 0.2870 0.2012 0.0448  0.0355  -0.0740 324 GLN C NE2 
6269 N N   . LEU C 69 ? 0.2141 0.1975 0.0890 -0.0009 0.0199  0.0108  325 LEU C N   
6270 C CA  . LEU C 69 ? 0.2187 0.1826 0.0918 -0.0035 -0.0053 -0.0074 325 LEU C CA  
6271 C C   . LEU C 69 ? 0.2274 0.1858 0.0901 -0.0217 -0.0046 -0.0128 325 LEU C C   
6272 O O   . LEU C 69 ? 0.2748 0.2147 0.0925 0.0127  0.0230  0.0091  325 LEU C O   
6273 C CB  . LEU C 69 ? 0.2278 0.1795 0.0886 -0.0171 -0.0020 0.0090  325 LEU C CB  
6274 C CG  . LEU C 69 ? 0.2490 0.2170 0.1027 0.0361  0.0198  0.0132  325 LEU C CG  
6275 C CD1 . LEU C 69 ? 0.3022 0.2426 0.1143 0.0548  -0.0024 0.0163  325 LEU C CD1 
6276 C CD2 . LEU C 69 ? 0.2776 0.2177 0.0900 0.0399  0.0151  -0.0035 325 LEU C CD2 
6277 N N   . GLY C 70 ? 0.2371 0.1984 0.0981 -0.0289 0.0149  -0.0258 326 GLY C N   
6278 C CA  . GLY C 70 ? 0.2631 0.2074 0.1160 -0.0037 0.0172  -0.0204 326 GLY C CA  
6279 C C   . GLY C 70 ? 0.2757 0.2079 0.1123 -0.0024 0.0404  -0.0205 326 GLY C C   
6280 O O   . GLY C 70 ? 0.2192 0.2507 0.1419 0.0009  0.0338  -0.0227 326 GLY C O   
6281 N N   . ASP C 71 ? 0.3328 0.2362 0.1170 -0.0390 0.0526  -0.0302 327 ASP C N   
6282 C CA  . ASP C 71 ? 0.3681 0.2808 0.1336 -0.0216 0.0845  -0.0391 327 ASP C CA  
6283 C C   . ASP C 71 ? 0.3217 0.2603 0.1414 -0.0146 0.0863  -0.0119 327 ASP C C   
6284 O O   . ASP C 71 ? 0.3223 0.2739 0.1816 -0.0551 0.0903  -0.0088 327 ASP C O   
6285 C CB  . ASP C 71 ? 0.4880 0.3833 0.1642 -0.0578 0.1005  -0.0248 327 ASP C CB  
6286 C CG  . ASP C 71 ? 0.6050 0.5561 0.1802 -0.0588 0.0834  0.0103  327 ASP C CG  
6287 O OD1 . ASP C 71 ? 0.6487 0.6167 0.1841 -0.0422 0.0702  -0.0162 327 ASP C OD1 
6288 O OD2 . ASP C 71 ? 0.6741 0.6407 0.1881 -0.0459 0.0630  0.0308  327 ASP C OD2 
6289 N N   . LYS C 72 ? 0.2644 0.2301 0.1054 -0.0089 0.0495  -0.0281 328 LYS C N   
6290 C CA  . LYS C 72 ? 0.2560 0.2181 0.1039 -0.0031 0.0367  -0.0137 328 LYS C CA  
6291 C C   . LYS C 72 ? 0.2368 0.2321 0.0977 -0.0211 0.0571  -0.0147 328 LYS C C   
6292 O O   . LYS C 72 ? 0.2933 0.2323 0.1136 -0.0456 0.0280  0.0096  328 LYS C O   
6293 C CB  . LYS C 72 ? 0.3545 0.2455 0.1417 0.0383  0.0321  0.0037  328 LYS C CB  
6294 C CG  . LYS C 72 ? 0.4385 0.2965 0.1686 0.0770  0.0519  0.0263  328 LYS C CG  
6295 C CD  . LYS C 72 ? 0.5358 0.3525 0.1798 0.0887  0.0872  0.0567  328 LYS C CD  
6296 C CE  . LYS C 72 ? 0.6323 0.4103 0.2034 0.0901  0.0972  0.0662  328 LYS C CE  
6297 N NZ  . LYS C 72 ? 0.6928 0.4643 0.2301 0.0980  0.0953  0.0736  328 LYS C NZ  
6298 N N   . LYS C 73 ? 0.2691 0.2214 0.0958 -0.0107 0.0518  -0.0183 329 LYS C N   
6299 C CA  . LYS C 73 ? 0.2403 0.2486 0.1172 0.0296  0.0353  -0.0276 329 LYS C CA  
6300 C C   . LYS C 73 ? 0.2146 0.2151 0.0925 0.0250  0.0251  0.0036  329 LYS C C   
6301 O O   . LYS C 73 ? 0.2708 0.2130 0.1100 0.0216  0.0363  0.0151  329 LYS C O   
6302 C CB  . LYS C 73 ? 0.2483 0.3322 0.1584 0.0361  0.0313  -0.0353 329 LYS C CB  
6303 C CG  . LYS C 73 ? 0.2370 0.3804 0.1723 0.0521  0.0625  -0.0361 329 LYS C CG  
6304 C CD  . LYS C 73 ? 0.2640 0.4689 0.1999 0.0654  0.0532  -0.0259 329 LYS C CD  
6305 C CE  . LYS C 73 ? 0.3028 0.5302 0.2148 0.0533  0.0376  -0.0172 329 LYS C CE  
6306 N NZ  . LYS C 73 ? 0.3798 0.5662 0.2273 0.0488  0.0218  -0.0193 329 LYS C NZ  
6307 N N   . LEU C 74 ? 0.1785 0.1899 0.0690 -0.0012 0.0160  0.0038  330 LEU C N   
6308 C CA  . LEU C 74 ? 0.1478 0.1912 0.0620 0.0037  0.0117  -0.0025 330 LEU C CA  
6309 C C   . LEU C 74 ? 0.1413 0.1963 0.0628 -0.0053 0.0151  -0.0008 330 LEU C C   
6310 O O   . LEU C 74 ? 0.1480 0.2263 0.0722 -0.0035 0.0111  -0.0044 330 LEU C O   
6311 C CB  . LEU C 74 ? 0.1474 0.1834 0.0719 -0.0085 -0.0069 0.0072  330 LEU C CB  
6312 C CG  . LEU C 74 ? 0.1686 0.1878 0.0781 -0.0028 -0.0215 0.0119  330 LEU C CG  
6313 C CD1 . LEU C 74 ? 0.1619 0.2066 0.1063 -0.0132 -0.0024 0.0057  330 LEU C CD1 
6314 C CD2 . LEU C 74 ? 0.1812 0.2038 0.1209 -0.0247 -0.0450 0.0168  330 LEU C CD2 
6315 N N   . LEU C 75 ? 0.1416 0.1859 0.0691 -0.0101 0.0048  -0.0053 331 LEU C N   
6316 C CA  . LEU C 75 ? 0.1463 0.1834 0.0781 -0.0010 0.0053  -0.0020 331 LEU C CA  
6317 C C   . LEU C 75 ? 0.1395 0.1793 0.0711 -0.0138 0.0038  -0.0111 331 LEU C C   
6318 O O   . LEU C 75 ? 0.1511 0.1884 0.0629 -0.0007 -0.0079 -0.0145 331 LEU C O   
6319 C CB  . LEU C 75 ? 0.1715 0.1871 0.1213 -0.0259 0.0301  -0.0001 331 LEU C CB  
6320 C CG  . LEU C 75 ? 0.1928 0.2114 0.1622 -0.0252 0.0440  -0.0048 331 LEU C CG  
6321 C CD1 . LEU C 75 ? 0.1650 0.2644 0.1849 -0.0413 -0.0058 0.0031  331 LEU C CD1 
6322 C CD2 . LEU C 75 ? 0.2131 0.2300 0.1835 -0.0392 0.0410  0.0014  331 LEU C CD2 
6323 N N   . VAL C 76 ? 0.1313 0.2006 0.0693 -0.0103 0.0117  -0.0005 332 VAL C N   
6324 C CA  . VAL C 76 ? 0.1336 0.1949 0.0634 -0.0144 -0.0167 0.0003  332 VAL C CA  
6325 C C   . VAL C 76 ? 0.1441 0.2155 0.0805 -0.0110 -0.0131 -0.0109 332 VAL C C   
6326 O O   . VAL C 76 ? 0.1508 0.2534 0.0977 0.0000  -0.0183 -0.0303 332 VAL C O   
6327 C CB  . VAL C 76 ? 0.1445 0.1967 0.0799 0.0084  0.0064  0.0153  332 VAL C CB  
6328 C CG1 . VAL C 76 ? 0.1451 0.2140 0.0914 -0.0001 0.0005  0.0143  332 VAL C CG1 
6329 C CG2 . VAL C 76 ? 0.1407 0.1859 0.1185 0.0093  0.0061  0.0117  332 VAL C CG2 
6330 N N   . GLN C 77 ? 0.1561 0.1959 0.0777 0.0220  -0.0503 0.0008  333 GLN C N   
6331 C CA  . GLN C 77 ? 0.1684 0.1954 0.0684 0.0209  -0.0421 0.0026  333 GLN C CA  
6332 C C   . GLN C 77 ? 0.1835 0.1886 0.0644 0.0204  -0.0349 0.0150  333 GLN C C   
6333 O O   . GLN C 77 ? 0.1486 0.1878 0.0531 -0.0113 -0.0134 0.0205  333 GLN C O   
6334 C CB  . GLN C 77 ? 0.1583 0.1738 0.0584 0.0035  -0.0403 0.0002  333 GLN C CB  
6335 C CG  . GLN C 77 ? 0.1219 0.1691 0.0590 0.0030  -0.0179 0.0066  333 GLN C CG  
6336 C CD  . GLN C 77 ? 0.1457 0.1521 0.0683 -0.0263 -0.0303 0.0099  333 GLN C CD  
6337 O OE1 . GLN C 77 ? 0.1342 0.1766 0.0717 -0.0245 0.0154  -0.0044 333 GLN C OE1 
6338 N NE2 . GLN C 77 ? 0.1633 0.1692 0.0840 -0.0258 -0.0090 0.0080  333 GLN C NE2 
6339 N N   . ARG C 78 ? 0.2036 0.2295 0.0871 -0.0136 -0.0560 0.0201  334 ARG C N   
6340 C CA  . ARG C 78 ? 0.2275 0.1978 0.0870 -0.0381 -0.0349 0.0321  334 ARG C CA  
6341 C C   . ARG C 78 ? 0.2165 0.2131 0.1107 -0.0531 0.0115  0.0391  334 ARG C C   
6342 O O   . ARG C 78 ? 0.2092 0.1972 0.1167 -0.0142 0.0233  0.0146  334 ARG C O   
6343 C CB  . ARG C 78 ? 0.2738 0.2114 0.0811 -0.0150 -0.0297 0.0169  334 ARG C CB  
6344 C CG  . ARG C 78 ? 0.3138 0.2160 0.0853 -0.0074 -0.0329 0.0123  334 ARG C CG  
6345 C CD  . ARG C 78 ? 0.3043 0.2269 0.0968 -0.0087 -0.0173 -0.0118 334 ARG C CD  
6346 N NE  . ARG C 78 ? 0.2534 0.2021 0.1061 -0.0229 -0.0253 -0.0006 334 ARG C NE  
6347 C CZ  . ARG C 78 ? 0.2725 0.2014 0.1100 -0.0105 -0.0352 -0.0081 334 ARG C CZ  
6348 N NH1 . ARG C 78 ? 0.2679 0.2953 0.1226 -0.0305 -0.0212 -0.0729 334 ARG C NH1 
6349 N NH2 . ARG C 78 ? 0.2813 0.2069 0.1098 0.0186  -0.0285 -0.0263 334 ARG C NH2 
6350 N N   . ALA C 79 ? 0.1943 0.2474 0.1738 0.0036  0.0739  0.0886  335 ALA C N   
6351 C CA  . ALA C 79 ? 0.2929 0.3475 0.2741 -0.0182 0.0789  0.1451  335 ALA C CA  
6352 C C   . ALA C 79 ? 0.4377 0.4998 0.3572 0.0155  0.0519  0.1335  335 ALA C C   
6353 O O   . ALA C 79 ? 0.4501 0.4952 0.3841 0.0262  0.0633  0.1299  335 ALA C O   
6354 C CB  . ALA C 79 ? 0.2691 0.3118 0.2921 -0.0104 0.0505  0.1698  335 ALA C CB  
6355 N N   . SER C 80 ? 0.5576 0.6588 0.4246 0.0453  0.0262  0.1207  336 SER C N   
6356 C CA  . SER C 80 ? 0.6535 0.8038 0.4823 0.0727  0.0069  0.1078  336 SER C CA  
6357 C C   . SER C 80 ? 0.7200 0.9144 0.5030 0.0592  0.0087  0.0920  336 SER C C   
6358 O O   . SER C 80 ? 0.7454 0.9595 0.5106 0.0515  0.0111  0.0781  336 SER C O   
6359 C CB  . SER C 80 ? 0.6592 0.8229 0.5045 0.1122  -0.0138 0.1103  336 SER C CB  
6360 O OG  . SER C 80 ? 0.6592 0.8280 0.5148 0.1320  -0.0253 0.1098  336 SER C OG  
6361 O OXT . SER C 80 ? 0.7401 0.9537 0.5070 0.0565  0.0071  0.0958  336 SER C OXT 
# 
