data_9DTQ
# 
_entry.id   9DTQ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DTQ         pdb_00009dtq 10.2210/pdb9dtq/pdb 
WWPDB D_1000288742 ?            ?                   
EMDB  EMD-47156    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_database_PDB_caveat.id     1 
_database_PDB_caveat.text   
'Residues LYS D 133 and LYS D 134 that are next to each other in the sample sequence are not properly linked.' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DTQ 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'The structure of HDAC2-CoREST in complex with KBTBD4R313PRR mutant' 
_pdbx_database_related.db_id          EMD-47156 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              nzheng@uw.edu 
_pdbx_contact_author.name_first         Ning 
_pdbx_contact_author.name_last          Zheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1039-1581 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xie, X.'   1 0000-0002-9884-1865 
'Liau, B.'  2 ?                   
'Zheng, N.' 3 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Molecular Mechanism Underlying KBTBD4 Cancer Mutation-Driven Degradation of HDAC Corepressor Complexes' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xie, X.'   1 ? 
primary 'Liau, B.'  2 ? 
primary 'Zheng, N.' 3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Histone deacetylase 2'                            55311.961 1 3.5.1.98,3.5.1.- ? ? ? 
2 polymer     man 'Kelch repeat and BTB domain-containing protein 4' 58463.059 2 ?                ? ? ? 
3 polymer     man 'REST corepressor 1'                               45974.441 1 ?                ? ? ? 
4 non-polymer syn 'INOSITOL HEXAKISPHOSPHATE'                        660.035   1 ?                ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'HD2,Protein deacylase HDAC2'               
2 'BTB and kelch domain-containing protein 4' 
3 'Protein CoREST'                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;AYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIR
PDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAI
LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQI
FKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVAL
DCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGED
PDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTK
SEQLSNP
;
;AYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIR
PDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAI
LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQI
FKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVAL
DCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGED
PDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTK
SEQLSNP
;
A   ? 
2 'polypeptide(L)' no no 
;MESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKE
AHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDP
ELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFAESLRTSLKEIGENVHI
YLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRPRRMWKCNNATVDWEWCAPLPRDR
LQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSR
LIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYV
FRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
;MESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKE
AHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDP
ELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFAESLRTSLKEIGENVHI
YLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRPRRMWKCNNATVDWEWCAPLPRDR
LQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSR
LIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYV
FRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
B,E ? 
3 'polypeptide(L)' no no 
;MSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNM
EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTS
VMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDV
EAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRD
FQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVRYASA
S
;
;MSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNM
EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTS
VMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDV
EAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRD
FQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVRYASA
S
;
D   ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        'INOSITOL HEXAKISPHOSPHATE' 
_pdbx_entity_nonpoly.comp_id     IHP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   TYR n 
1 3   SER n 
1 4   GLN n 
1 5   GLY n 
1 6   GLY n 
1 7   GLY n 
1 8   LYS n 
1 9   LYS n 
1 10  LYS n 
1 11  VAL n 
1 12  CYS n 
1 13  TYR n 
1 14  TYR n 
1 15  TYR n 
1 16  ASP n 
1 17  GLY n 
1 18  ASP n 
1 19  ILE n 
1 20  GLY n 
1 21  ASN n 
1 22  TYR n 
1 23  TYR n 
1 24  TYR n 
1 25  GLY n 
1 26  GLN n 
1 27  GLY n 
1 28  HIS n 
1 29  PRO n 
1 30  MET n 
1 31  LYS n 
1 32  PRO n 
1 33  HIS n 
1 34  ARG n 
1 35  ILE n 
1 36  ARG n 
1 37  MET n 
1 38  THR n 
1 39  HIS n 
1 40  ASN n 
1 41  LEU n 
1 42  LEU n 
1 43  LEU n 
1 44  ASN n 
1 45  TYR n 
1 46  GLY n 
1 47  LEU n 
1 48  TYR n 
1 49  ARG n 
1 50  LYS n 
1 51  MET n 
1 52  GLU n 
1 53  ILE n 
1 54  TYR n 
1 55  ARG n 
1 56  PRO n 
1 57  HIS n 
1 58  LYS n 
1 59  ALA n 
1 60  THR n 
1 61  ALA n 
1 62  GLU n 
1 63  GLU n 
1 64  MET n 
1 65  THR n 
1 66  LYS n 
1 67  TYR n 
1 68  HIS n 
1 69  SER n 
1 70  ASP n 
1 71  GLU n 
1 72  TYR n 
1 73  ILE n 
1 74  LYS n 
1 75  PHE n 
1 76  LEU n 
1 77  ARG n 
1 78  SER n 
1 79  ILE n 
1 80  ARG n 
1 81  PRO n 
1 82  ASP n 
1 83  ASN n 
1 84  MET n 
1 85  SER n 
1 86  GLU n 
1 87  TYR n 
1 88  SER n 
1 89  LYS n 
1 90  GLN n 
1 91  MET n 
1 92  GLN n 
1 93  ARG n 
1 94  PHE n 
1 95  ASN n 
1 96  VAL n 
1 97  GLY n 
1 98  GLU n 
1 99  ASP n 
1 100 CYS n 
1 101 PRO n 
1 102 VAL n 
1 103 PHE n 
1 104 ASP n 
1 105 GLY n 
1 106 LEU n 
1 107 PHE n 
1 108 GLU n 
1 109 PHE n 
1 110 CYS n 
1 111 GLN n 
1 112 LEU n 
1 113 SER n 
1 114 THR n 
1 115 GLY n 
1 116 GLY n 
1 117 SER n 
1 118 VAL n 
1 119 ALA n 
1 120 GLY n 
1 121 ALA n 
1 122 VAL n 
1 123 LYS n 
1 124 LEU n 
1 125 ASN n 
1 126 ARG n 
1 127 GLN n 
1 128 GLN n 
1 129 THR n 
1 130 ASP n 
1 131 MET n 
1 132 ALA n 
1 133 VAL n 
1 134 ASN n 
1 135 TRP n 
1 136 ALA n 
1 137 GLY n 
1 138 GLY n 
1 139 LEU n 
1 140 HIS n 
1 141 HIS n 
1 142 ALA n 
1 143 LYS n 
1 144 LYS n 
1 145 SER n 
1 146 GLU n 
1 147 ALA n 
1 148 SER n 
1 149 GLY n 
1 150 PHE n 
1 151 CYS n 
1 152 TYR n 
1 153 VAL n 
1 154 ASN n 
1 155 ASP n 
1 156 ILE n 
1 157 VAL n 
1 158 LEU n 
1 159 ALA n 
1 160 ILE n 
1 161 LEU n 
1 162 GLU n 
1 163 LEU n 
1 164 LEU n 
1 165 LYS n 
1 166 TYR n 
1 167 HIS n 
1 168 GLN n 
1 169 ARG n 
1 170 VAL n 
1 171 LEU n 
1 172 TYR n 
1 173 ILE n 
1 174 ASP n 
1 175 ILE n 
1 176 ASP n 
1 177 ILE n 
1 178 HIS n 
1 179 HIS n 
1 180 GLY n 
1 181 ASP n 
1 182 GLY n 
1 183 VAL n 
1 184 GLU n 
1 185 GLU n 
1 186 ALA n 
1 187 PHE n 
1 188 TYR n 
1 189 THR n 
1 190 THR n 
1 191 ASP n 
1 192 ARG n 
1 193 VAL n 
1 194 MET n 
1 195 THR n 
1 196 VAL n 
1 197 SER n 
1 198 PHE n 
1 199 HIS n 
1 200 LYS n 
1 201 TYR n 
1 202 GLY n 
1 203 GLU n 
1 204 TYR n 
1 205 PHE n 
1 206 PRO n 
1 207 GLY n 
1 208 THR n 
1 209 GLY n 
1 210 ASP n 
1 211 LEU n 
1 212 ARG n 
1 213 ASP n 
1 214 ILE n 
1 215 GLY n 
1 216 ALA n 
1 217 GLY n 
1 218 LYS n 
1 219 GLY n 
1 220 LYS n 
1 221 TYR n 
1 222 TYR n 
1 223 ALA n 
1 224 VAL n 
1 225 ASN n 
1 226 PHE n 
1 227 PRO n 
1 228 MET n 
1 229 ARG n 
1 230 ASP n 
1 231 GLY n 
1 232 ILE n 
1 233 ASP n 
1 234 ASP n 
1 235 GLU n 
1 236 SER n 
1 237 TYR n 
1 238 GLY n 
1 239 GLN n 
1 240 ILE n 
1 241 PHE n 
1 242 LYS n 
1 243 PRO n 
1 244 ILE n 
1 245 ILE n 
1 246 SER n 
1 247 LYS n 
1 248 VAL n 
1 249 MET n 
1 250 GLU n 
1 251 MET n 
1 252 TYR n 
1 253 GLN n 
1 254 PRO n 
1 255 SER n 
1 256 ALA n 
1 257 VAL n 
1 258 VAL n 
1 259 LEU n 
1 260 GLN n 
1 261 CYS n 
1 262 GLY n 
1 263 ALA n 
1 264 ASP n 
1 265 SER n 
1 266 LEU n 
1 267 SER n 
1 268 GLY n 
1 269 ASP n 
1 270 ARG n 
1 271 LEU n 
1 272 GLY n 
1 273 CYS n 
1 274 PHE n 
1 275 ASN n 
1 276 LEU n 
1 277 THR n 
1 278 VAL n 
1 279 LYS n 
1 280 GLY n 
1 281 HIS n 
1 282 ALA n 
1 283 LYS n 
1 284 CYS n 
1 285 VAL n 
1 286 GLU n 
1 287 VAL n 
1 288 VAL n 
1 289 LYS n 
1 290 THR n 
1 291 PHE n 
1 292 ASN n 
1 293 LEU n 
1 294 PRO n 
1 295 LEU n 
1 296 LEU n 
1 297 MET n 
1 298 LEU n 
1 299 GLY n 
1 300 GLY n 
1 301 GLY n 
1 302 GLY n 
1 303 TYR n 
1 304 THR n 
1 305 ILE n 
1 306 ARG n 
1 307 ASN n 
1 308 VAL n 
1 309 ALA n 
1 310 ARG n 
1 311 CYS n 
1 312 TRP n 
1 313 THR n 
1 314 TYR n 
1 315 GLU n 
1 316 THR n 
1 317 ALA n 
1 318 VAL n 
1 319 ALA n 
1 320 LEU n 
1 321 ASP n 
1 322 CYS n 
1 323 GLU n 
1 324 ILE n 
1 325 PRO n 
1 326 ASN n 
1 327 GLU n 
1 328 LEU n 
1 329 PRO n 
1 330 TYR n 
1 331 ASN n 
1 332 ASP n 
1 333 TYR n 
1 334 PHE n 
1 335 GLU n 
1 336 TYR n 
1 337 PHE n 
1 338 GLY n 
1 339 PRO n 
1 340 ASP n 
1 341 PHE n 
1 342 LYS n 
1 343 LEU n 
1 344 HIS n 
1 345 ILE n 
1 346 SER n 
1 347 PRO n 
1 348 SER n 
1 349 ASN n 
1 350 MET n 
1 351 THR n 
1 352 ASN n 
1 353 GLN n 
1 354 ASN n 
1 355 THR n 
1 356 PRO n 
1 357 GLU n 
1 358 TYR n 
1 359 MET n 
1 360 GLU n 
1 361 LYS n 
1 362 ILE n 
1 363 LYS n 
1 364 GLN n 
1 365 ARG n 
1 366 LEU n 
1 367 PHE n 
1 368 GLU n 
1 369 ASN n 
1 370 LEU n 
1 371 ARG n 
1 372 MET n 
1 373 LEU n 
1 374 PRO n 
1 375 HIS n 
1 376 ALA n 
1 377 PRO n 
1 378 GLY n 
1 379 VAL n 
1 380 GLN n 
1 381 MET n 
1 382 GLN n 
1 383 ALA n 
1 384 ILE n 
1 385 PRO n 
1 386 GLU n 
1 387 ASP n 
1 388 ALA n 
1 389 VAL n 
1 390 HIS n 
1 391 GLU n 
1 392 ASP n 
1 393 SER n 
1 394 GLY n 
1 395 ASP n 
1 396 GLU n 
1 397 ASP n 
1 398 GLY n 
1 399 GLU n 
1 400 ASP n 
1 401 PRO n 
1 402 ASP n 
1 403 LYS n 
1 404 ARG n 
1 405 ILE n 
1 406 SER n 
1 407 ILE n 
1 408 ARG n 
1 409 ALA n 
1 410 SER n 
1 411 ASP n 
1 412 LYS n 
1 413 ARG n 
1 414 ILE n 
1 415 ALA n 
1 416 CYS n 
1 417 ASP n 
1 418 GLU n 
1 419 GLU n 
1 420 PHE n 
1 421 SER n 
1 422 ASP n 
1 423 SER n 
1 424 GLU n 
1 425 ASP n 
1 426 GLU n 
1 427 GLY n 
1 428 GLU n 
1 429 GLY n 
1 430 GLY n 
1 431 ARG n 
1 432 ARG n 
1 433 ASN n 
1 434 VAL n 
1 435 ALA n 
1 436 ASP n 
1 437 HIS n 
1 438 LYS n 
1 439 LYS n 
1 440 GLY n 
1 441 ALA n 
1 442 LYS n 
1 443 LYS n 
1 444 ALA n 
1 445 ARG n 
1 446 ILE n 
1 447 GLU n 
1 448 GLU n 
1 449 ASP n 
1 450 LYS n 
1 451 LYS n 
1 452 GLU n 
1 453 THR n 
1 454 GLU n 
1 455 ASP n 
1 456 LYS n 
1 457 LYS n 
1 458 THR n 
1 459 ASP n 
1 460 VAL n 
1 461 LYS n 
1 462 GLU n 
1 463 GLU n 
1 464 ASP n 
1 465 LYS n 
1 466 SER n 
1 467 LYS n 
1 468 ASP n 
1 469 ASN n 
1 470 SER n 
1 471 GLY n 
1 472 GLU n 
1 473 LYS n 
1 474 THR n 
1 475 ASP n 
1 476 THR n 
1 477 LYS n 
1 478 GLY n 
1 479 THR n 
1 480 LYS n 
1 481 SER n 
1 482 GLU n 
1 483 GLN n 
1 484 LEU n 
1 485 SER n 
1 486 ASN n 
1 487 PRO n 
2 1   MET n 
2 2   GLU n 
2 3   SER n 
2 4   PRO n 
2 5   GLU n 
2 6   GLU n 
2 7   PRO n 
2 8   GLY n 
2 9   ALA n 
2 10  SER n 
2 11  MET n 
2 12  ASP n 
2 13  GLU n 
2 14  ASN n 
2 15  TYR n 
2 16  PHE n 
2 17  VAL n 
2 18  ASN n 
2 19  TYR n 
2 20  THR n 
2 21  PHE n 
2 22  LYS n 
2 23  ASP n 
2 24  ARG n 
2 25  SER n 
2 26  HIS n 
2 27  SER n 
2 28  GLY n 
2 29  ARG n 
2 30  VAL n 
2 31  ALA n 
2 32  GLN n 
2 33  GLY n 
2 34  ILE n 
2 35  MET n 
2 36  LYS n 
2 37  LEU n 
2 38  CYS n 
2 39  LEU n 
2 40  GLU n 
2 41  GLU n 
2 42  GLU n 
2 43  LEU n 
2 44  PHE n 
2 45  ALA n 
2 46  ASP n 
2 47  VAL n 
2 48  THR n 
2 49  ILE n 
2 50  SER n 
2 51  VAL n 
2 52  GLU n 
2 53  GLY n 
2 54  ARG n 
2 55  GLU n 
2 56  PHE n 
2 57  GLN n 
2 58  LEU n 
2 59  HIS n 
2 60  ARG n 
2 61  LEU n 
2 62  VAL n 
2 63  LEU n 
2 64  SER n 
2 65  ALA n 
2 66  GLN n 
2 67  SER n 
2 68  CYS n 
2 69  PHE n 
2 70  PHE n 
2 71  ARG n 
2 72  SER n 
2 73  MET n 
2 74  PHE n 
2 75  THR n 
2 76  SER n 
2 77  ASN n 
2 78  LEU n 
2 79  LYS n 
2 80  GLU n 
2 81  ALA n 
2 82  HIS n 
2 83  ASN n 
2 84  ARG n 
2 85  VAL n 
2 86  ILE n 
2 87  VAL n 
2 88  LEU n 
2 89  GLN n 
2 90  ASP n 
2 91  VAL n 
2 92  SER n 
2 93  GLU n 
2 94  SER n 
2 95  VAL n 
2 96  PHE n 
2 97  GLN n 
2 98  LEU n 
2 99  LEU n 
2 100 VAL n 
2 101 ASP n 
2 102 TYR n 
2 103 ILE n 
2 104 TYR n 
2 105 HIS n 
2 106 GLY n 
2 107 THR n 
2 108 VAL n 
2 109 LYS n 
2 110 LEU n 
2 111 ARG n 
2 112 ALA n 
2 113 GLU n 
2 114 GLU n 
2 115 LEU n 
2 116 GLN n 
2 117 GLU n 
2 118 ILE n 
2 119 TYR n 
2 120 GLU n 
2 121 VAL n 
2 122 SER n 
2 123 ASP n 
2 124 MET n 
2 125 TYR n 
2 126 GLN n 
2 127 LEU n 
2 128 THR n 
2 129 SER n 
2 130 LEU n 
2 131 PHE n 
2 132 GLU n 
2 133 GLU n 
2 134 CYS n 
2 135 SER n 
2 136 ARG n 
2 137 PHE n 
2 138 LEU n 
2 139 ALA n 
2 140 ARG n 
2 141 THR n 
2 142 VAL n 
2 143 GLN n 
2 144 VAL n 
2 145 GLY n 
2 146 ASN n 
2 147 CYS n 
2 148 LEU n 
2 149 GLN n 
2 150 VAL n 
2 151 MET n 
2 152 TRP n 
2 153 LEU n 
2 154 ALA n 
2 155 ASP n 
2 156 ARG n 
2 157 HIS n 
2 158 SER n 
2 159 ASP n 
2 160 PRO n 
2 161 GLU n 
2 162 LEU n 
2 163 TYR n 
2 164 THR n 
2 165 ALA n 
2 166 ALA n 
2 167 LYS n 
2 168 HIS n 
2 169 CYS n 
2 170 ALA n 
2 171 LYS n 
2 172 THR n 
2 173 HIS n 
2 174 LEU n 
2 175 ALA n 
2 176 GLN n 
2 177 LEU n 
2 178 GLN n 
2 179 ASN n 
2 180 THR n 
2 181 GLU n 
2 182 GLU n 
2 183 PHE n 
2 184 LEU n 
2 185 HIS n 
2 186 LEU n 
2 187 PRO n 
2 188 HIS n 
2 189 ARG n 
2 190 LEU n 
2 191 LEU n 
2 192 THR n 
2 193 ASP n 
2 194 ILE n 
2 195 ILE n 
2 196 SER n 
2 197 ASP n 
2 198 GLY n 
2 199 VAL n 
2 200 PRO n 
2 201 CYS n 
2 202 SER n 
2 203 GLN n 
2 204 ASN n 
2 205 PRO n 
2 206 THR n 
2 207 GLU n 
2 208 ALA n 
2 209 ILE n 
2 210 GLU n 
2 211 ALA n 
2 212 TRP n 
2 213 ILE n 
2 214 ASN n 
2 215 PHE n 
2 216 ASN n 
2 217 LYS n 
2 218 GLU n 
2 219 GLU n 
2 220 ARG n 
2 221 GLU n 
2 222 ALA n 
2 223 PHE n 
2 224 ALA n 
2 225 GLU n 
2 226 SER n 
2 227 LEU n 
2 228 ARG n 
2 229 THR n 
2 230 SER n 
2 231 LEU n 
2 232 LYS n 
2 233 GLU n 
2 234 ILE n 
2 235 GLY n 
2 236 GLU n 
2 237 ASN n 
2 238 VAL n 
2 239 HIS n 
2 240 ILE n 
2 241 TYR n 
2 242 LEU n 
2 243 ILE n 
2 244 GLY n 
2 245 LYS n 
2 246 GLU n 
2 247 SER n 
2 248 SER n 
2 249 ARG n 
2 250 THR n 
2 251 HIS n 
2 252 SER n 
2 253 LEU n 
2 254 ALA n 
2 255 VAL n 
2 256 SER n 
2 257 LEU n 
2 258 HIS n 
2 259 CYS n 
2 260 ALA n 
2 261 GLU n 
2 262 ASP n 
2 263 ASP n 
2 264 SER n 
2 265 ILE n 
2 266 SER n 
2 267 VAL n 
2 268 SER n 
2 269 GLY n 
2 270 GLN n 
2 271 ASN n 
2 272 SER n 
2 273 LEU n 
2 274 CYS n 
2 275 HIS n 
2 276 GLN n 
2 277 ILE n 
2 278 THR n 
2 279 ALA n 
2 280 ALA n 
2 281 CYS n 
2 282 LYS n 
2 283 HIS n 
2 284 GLY n 
2 285 GLY n 
2 286 ASP n 
2 287 LEU n 
2 288 TYR n 
2 289 VAL n 
2 290 VAL n 
2 291 GLY n 
2 292 GLY n 
2 293 SER n 
2 294 ILE n 
2 295 PRO n 
2 296 ARG n 
2 297 PRO n 
2 298 ARG n 
2 299 ARG n 
2 300 MET n 
2 301 TRP n 
2 302 LYS n 
2 303 CYS n 
2 304 ASN n 
2 305 ASN n 
2 306 ALA n 
2 307 THR n 
2 308 VAL n 
2 309 ASP n 
2 310 TRP n 
2 311 GLU n 
2 312 TRP n 
2 313 CYS n 
2 314 ALA n 
2 315 PRO n 
2 316 LEU n 
2 317 PRO n 
2 318 ARG n 
2 319 ASP n 
2 320 ARG n 
2 321 LEU n 
2 322 GLN n 
2 323 HIS n 
2 324 THR n 
2 325 LEU n 
2 326 VAL n 
2 327 SER n 
2 328 VAL n 
2 329 PRO n 
2 330 GLY n 
2 331 LYS n 
2 332 ASP n 
2 333 ALA n 
2 334 ILE n 
2 335 TYR n 
2 336 SER n 
2 337 LEU n 
2 338 GLY n 
2 339 GLY n 
2 340 LYS n 
2 341 THR n 
2 342 LEU n 
2 343 GLN n 
2 344 ASP n 
2 345 THR n 
2 346 LEU n 
2 347 SER n 
2 348 ASN n 
2 349 ALA n 
2 350 VAL n 
2 351 ILE n 
2 352 TYR n 
2 353 TYR n 
2 354 ARG n 
2 355 VAL n 
2 356 GLY n 
2 357 ASP n 
2 358 ASN n 
2 359 VAL n 
2 360 TRP n 
2 361 THR n 
2 362 GLU n 
2 363 THR n 
2 364 THR n 
2 365 GLN n 
2 366 LEU n 
2 367 GLU n 
2 368 VAL n 
2 369 ALA n 
2 370 VAL n 
2 371 SER n 
2 372 GLY n 
2 373 ALA n 
2 374 ALA n 
2 375 GLY n 
2 376 ALA n 
2 377 ASN n 
2 378 LEU n 
2 379 ASN n 
2 380 GLY n 
2 381 ILE n 
2 382 ILE n 
2 383 TYR n 
2 384 LEU n 
2 385 LEU n 
2 386 GLY n 
2 387 GLY n 
2 388 GLU n 
2 389 GLU n 
2 390 ASN n 
2 391 ASP n 
2 392 LEU n 
2 393 ASP n 
2 394 PHE n 
2 395 PHE n 
2 396 THR n 
2 397 LYS n 
2 398 PRO n 
2 399 SER n 
2 400 ARG n 
2 401 LEU n 
2 402 ILE n 
2 403 GLN n 
2 404 CYS n 
2 405 PHE n 
2 406 ASP n 
2 407 THR n 
2 408 GLU n 
2 409 THR n 
2 410 ASP n 
2 411 LYS n 
2 412 CYS n 
2 413 HIS n 
2 414 VAL n 
2 415 LYS n 
2 416 PRO n 
2 417 TYR n 
2 418 VAL n 
2 419 LEU n 
2 420 PRO n 
2 421 PHE n 
2 422 ALA n 
2 423 GLY n 
2 424 ARG n 
2 425 MET n 
2 426 HIS n 
2 427 ALA n 
2 428 ALA n 
2 429 VAL n 
2 430 HIS n 
2 431 LYS n 
2 432 ASP n 
2 433 LEU n 
2 434 VAL n 
2 435 PHE n 
2 436 ILE n 
2 437 VAL n 
2 438 ALA n 
2 439 GLU n 
2 440 GLY n 
2 441 ASP n 
2 442 SER n 
2 443 LEU n 
2 444 VAL n 
2 445 CYS n 
2 446 TYR n 
2 447 ASN n 
2 448 PRO n 
2 449 LEU n 
2 450 LEU n 
2 451 ASP n 
2 452 SER n 
2 453 PHE n 
2 454 THR n 
2 455 ARG n 
2 456 LEU n 
2 457 CYS n 
2 458 LEU n 
2 459 PRO n 
2 460 GLU n 
2 461 ALA n 
2 462 TRP n 
2 463 SER n 
2 464 SER n 
2 465 ALA n 
2 466 PRO n 
2 467 SER n 
2 468 LEU n 
2 469 TRP n 
2 470 LYS n 
2 471 ILE n 
2 472 ALA n 
2 473 SER n 
2 474 CYS n 
2 475 ASN n 
2 476 GLY n 
2 477 SER n 
2 478 ILE n 
2 479 TYR n 
2 480 VAL n 
2 481 PHE n 
2 482 ARG n 
2 483 ASP n 
2 484 ARG n 
2 485 TYR n 
2 486 LYS n 
2 487 LYS n 
2 488 GLY n 
2 489 ASP n 
2 490 ALA n 
2 491 ASN n 
2 492 THR n 
2 493 TYR n 
2 494 LYS n 
2 495 LEU n 
2 496 ASP n 
2 497 PRO n 
2 498 ALA n 
2 499 THR n 
2 500 SER n 
2 501 ALA n 
2 502 VAL n 
2 503 THR n 
2 504 VAL n 
2 505 THR n 
2 506 ARG n 
2 507 GLY n 
2 508 ILE n 
2 509 LYS n 
2 510 VAL n 
2 511 LEU n 
2 512 LEU n 
2 513 THR n 
2 514 ASN n 
2 515 LEU n 
2 516 GLN n 
2 517 PHE n 
2 518 VAL n 
2 519 LEU n 
2 520 ALA n 
3 1   MET n 
3 2   SER n 
3 3   TRP n 
3 4   GLU n 
3 5   GLU n 
3 6   GLY n 
3 7   SER n 
3 8   SER n 
3 9   GLY n 
3 10  SER n 
3 11  SER n 
3 12  SER n 
3 13  ASP n 
3 14  GLU n 
3 15  GLU n 
3 16  HIS n 
3 17  GLY n 
3 18  GLY n 
3 19  GLY n 
3 20  GLY n 
3 21  MET n 
3 22  ARG n 
3 23  VAL n 
3 24  GLY n 
3 25  PRO n 
3 26  GLN n 
3 27  TYR n 
3 28  GLN n 
3 29  ALA n 
3 30  VAL n 
3 31  VAL n 
3 32  PRO n 
3 33  ASP n 
3 34  PHE n 
3 35  ASP n 
3 36  PRO n 
3 37  ALA n 
3 38  LYS n 
3 39  LEU n 
3 40  ALA n 
3 41  ARG n 
3 42  ARG n 
3 43  SER n 
3 44  GLN n 
3 45  GLU n 
3 46  ARG n 
3 47  ASP n 
3 48  ASN n 
3 49  LEU n 
3 50  GLY n 
3 51  MET n 
3 52  LEU n 
3 53  VAL n 
3 54  TRP n 
3 55  SER n 
3 56  PRO n 
3 57  ASN n 
3 58  GLN n 
3 59  ASN n 
3 60  LEU n 
3 61  SER n 
3 62  GLU n 
3 63  ALA n 
3 64  LYS n 
3 65  LEU n 
3 66  ASP n 
3 67  GLU n 
3 68  TYR n 
3 69  ILE n 
3 70  ALA n 
3 71  ILE n 
3 72  ALA n 
3 73  LYS n 
3 74  GLU n 
3 75  LYS n 
3 76  HIS n 
3 77  GLY n 
3 78  TYR n 
3 79  ASN n 
3 80  MET n 
3 81  GLU n 
3 82  GLN n 
3 83  ALA n 
3 84  LEU n 
3 85  GLY n 
3 86  MET n 
3 87  LEU n 
3 88  PHE n 
3 89  TRP n 
3 90  HIS n 
3 91  LYS n 
3 92  HIS n 
3 93  ASN n 
3 94  ILE n 
3 95  GLU n 
3 96  LYS n 
3 97  SER n 
3 98  LEU n 
3 99  ALA n 
3 100 ASP n 
3 101 LEU n 
3 102 PRO n 
3 103 ASN n 
3 104 PHE n 
3 105 THR n 
3 106 PRO n 
3 107 PHE n 
3 108 PRO n 
3 109 ASP n 
3 110 GLU n 
3 111 TRP n 
3 112 THR n 
3 113 VAL n 
3 114 GLU n 
3 115 ASP n 
3 116 LYS n 
3 117 VAL n 
3 118 LEU n 
3 119 PHE n 
3 120 GLU n 
3 121 GLN n 
3 122 ALA n 
3 123 PHE n 
3 124 SER n 
3 125 PHE n 
3 126 HIS n 
3 127 GLY n 
3 128 LYS n 
3 129 THR n 
3 130 PHE n 
3 131 HIS n 
3 132 ARG n 
3 133 ILE n 
3 134 GLN n 
3 135 GLN n 
3 136 MET n 
3 137 LEU n 
3 138 PRO n 
3 139 ASP n 
3 140 LYS n 
3 141 SER n 
3 142 ILE n 
3 143 ALA n 
3 144 SER n 
3 145 LEU n 
3 146 VAL n 
3 147 LYS n 
3 148 PHE n 
3 149 TYR n 
3 150 TYR n 
3 151 SER n 
3 152 TRP n 
3 153 LYS n 
3 154 LYS n 
3 155 THR n 
3 156 ARG n 
3 157 THR n 
3 158 LYS n 
3 159 THR n 
3 160 SER n 
3 161 VAL n 
3 162 MET n 
3 163 ASP n 
3 164 ARG n 
3 165 HIS n 
3 166 ALA n 
3 167 ARG n 
3 168 LYS n 
3 169 GLN n 
3 170 LYS n 
3 171 ARG n 
3 172 GLU n 
3 173 ARG n 
3 174 GLU n 
3 175 GLU n 
3 176 SER n 
3 177 GLU n 
3 178 ASP n 
3 179 GLU n 
3 180 LEU n 
3 181 GLU n 
3 182 GLU n 
3 183 ALA n 
3 184 ASN n 
3 185 GLY n 
3 186 ASN n 
3 187 ASN n 
3 188 PRO n 
3 189 ILE n 
3 190 ASP n 
3 191 ILE n 
3 192 GLU n 
3 193 VAL n 
3 194 ASP n 
3 195 GLN n 
3 196 ASN n 
3 197 LYS n 
3 198 GLU n 
3 199 SER n 
3 200 LYS n 
3 201 LYS n 
3 202 GLU n 
3 203 VAL n 
3 204 PRO n 
3 205 PRO n 
3 206 THR n 
3 207 GLU n 
3 208 THR n 
3 209 VAL n 
3 210 PRO n 
3 211 GLN n 
3 212 VAL n 
3 213 LYS n 
3 214 LYS n 
3 215 GLU n 
3 216 LYS n 
3 217 HIS n 
3 218 SER n 
3 219 THR n 
3 220 GLN n 
3 221 ALA n 
3 222 LYS n 
3 223 ASN n 
3 224 ARG n 
3 225 ALA n 
3 226 LYS n 
3 227 ARG n 
3 228 LYS n 
3 229 PRO n 
3 230 PRO n 
3 231 LYS n 
3 232 GLY n 
3 233 MET n 
3 234 PHE n 
3 235 LEU n 
3 236 SER n 
3 237 GLN n 
3 238 GLU n 
3 239 ASP n 
3 240 VAL n 
3 241 GLU n 
3 242 ALA n 
3 243 VAL n 
3 244 SER n 
3 245 ALA n 
3 246 ASN n 
3 247 ALA n 
3 248 THR n 
3 249 ALA n 
3 250 ALA n 
3 251 THR n 
3 252 THR n 
3 253 VAL n 
3 254 LEU n 
3 255 ARG n 
3 256 GLN n 
3 257 LEU n 
3 258 ASP n 
3 259 MET n 
3 260 GLU n 
3 261 LEU n 
3 262 VAL n 
3 263 SER n 
3 264 VAL n 
3 265 LYS n 
3 266 ARG n 
3 267 GLN n 
3 268 ILE n 
3 269 GLN n 
3 270 ASN n 
3 271 ILE n 
3 272 LYS n 
3 273 GLN n 
3 274 THR n 
3 275 ASN n 
3 276 SER n 
3 277 ALA n 
3 278 LEU n 
3 279 LYS n 
3 280 GLU n 
3 281 LYS n 
3 282 LEU n 
3 283 ASP n 
3 284 GLY n 
3 285 GLY n 
3 286 ILE n 
3 287 GLU n 
3 288 PRO n 
3 289 TYR n 
3 290 ARG n 
3 291 LEU n 
3 292 PRO n 
3 293 GLU n 
3 294 VAL n 
3 295 ILE n 
3 296 GLN n 
3 297 LYS n 
3 298 CYS n 
3 299 ASN n 
3 300 ALA n 
3 301 ARG n 
3 302 TRP n 
3 303 THR n 
3 304 THR n 
3 305 GLU n 
3 306 GLU n 
3 307 GLN n 
3 308 LEU n 
3 309 LEU n 
3 310 ALA n 
3 311 VAL n 
3 312 GLN n 
3 313 ALA n 
3 314 ILE n 
3 315 ARG n 
3 316 LYS n 
3 317 TYR n 
3 318 GLY n 
3 319 ARG n 
3 320 ASP n 
3 321 PHE n 
3 322 GLN n 
3 323 ALA n 
3 324 ILE n 
3 325 SER n 
3 326 ASP n 
3 327 VAL n 
3 328 ILE n 
3 329 GLY n 
3 330 ASN n 
3 331 LYS n 
3 332 SER n 
3 333 VAL n 
3 334 VAL n 
3 335 GLN n 
3 336 VAL n 
3 337 LYS n 
3 338 ASN n 
3 339 PHE n 
3 340 PHE n 
3 341 VAL n 
3 342 ASN n 
3 343 TYR n 
3 344 ARG n 
3 345 ARG n 
3 346 ARG n 
3 347 PHE n 
3 348 ASN n 
3 349 ILE n 
3 350 ASP n 
3 351 GLU n 
3 352 VAL n 
3 353 LEU n 
3 354 GLN n 
3 355 GLU n 
3 356 TRP n 
3 357 GLU n 
3 358 ALA n 
3 359 GLU n 
3 360 HIS n 
3 361 GLY n 
3 362 LYS n 
3 363 GLU n 
3 364 GLU n 
3 365 THR n 
3 366 ASN n 
3 367 GLY n 
3 368 PRO n 
3 369 SER n 
3 370 ASN n 
3 371 GLN n 
3 372 LYS n 
3 373 PRO n 
3 374 VAL n 
3 375 LYS n 
3 376 SER n 
3 377 PRO n 
3 378 ASP n 
3 379 ASN n 
3 380 SER n 
3 381 ILE n 
3 382 LYS n 
3 383 MET n 
3 384 PRO n 
3 385 GLU n 
3 386 GLU n 
3 387 GLU n 
3 388 ASP n 
3 389 GLU n 
3 390 ALA n 
3 391 PRO n 
3 392 VAL n 
3 393 LEU n 
3 394 ASP n 
3 395 VAL n 
3 396 ARG n 
3 397 TYR n 
3 398 ALA n 
3 399 SER n 
3 400 ALA n 
3 401 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 487 human ? HDAC2                   ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 520 human ? 'KBTBD4, BKLHD4'        ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni'       7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 401 human ? 'RCOR1, KIAA0071, RCOR' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                     ?                                                                      
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                    ?                                                                      
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ?                                                                      
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ?                                                                      
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                    ?                                                                      
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                   ?                                                                      
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ?                                                                      
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                     ?                                                                      
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                   ?                                                                      
'C6 H10 N3 O2 1' 156.162 
IHP non-polymer         . 'INOSITOL HEXAKISPHOSPHATE' 'MYO-INOSITOL HEXAKISPHOSPHATE; INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE' 
'C6 H18 O24 P6'  660.035 
ILE 'L-peptide linking' y ISOLEUCINE                  ?                                                                      
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                     ?                                                                      
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                      ?                                                                      
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                  ?                                                                      
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE               ?                                                                      
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                     ?                                                                      
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                      ?                                                                      
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                   ?                                                                      
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                  ?                                                                      
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                    ?                                                                      
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                      ?                                                                      
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   2   ?   ?   ?   A . n 
A 1 2   TYR 2   3   ?   ?   ?   A . n 
A 1 3   SER 3   4   ?   ?   ?   A . n 
A 1 4   GLN 4   5   ?   ?   ?   A . n 
A 1 5   GLY 5   6   ?   ?   ?   A . n 
A 1 6   GLY 6   7   ?   ?   ?   A . n 
A 1 7   GLY 7   8   ?   ?   ?   A . n 
A 1 8   LYS 8   9   9   LYS LYS A . n 
A 1 9   LYS 9   10  10  LYS LYS A . n 
A 1 10  LYS 10  11  11  LYS LYS A . n 
A 1 11  VAL 11  12  12  VAL VAL A . n 
A 1 12  CYS 12  13  13  CYS CYS A . n 
A 1 13  TYR 13  14  14  TYR TYR A . n 
A 1 14  TYR 14  15  15  TYR TYR A . n 
A 1 15  TYR 15  16  16  TYR TYR A . n 
A 1 16  ASP 16  17  17  ASP ASP A . n 
A 1 17  GLY 17  18  18  GLY GLY A . n 
A 1 18  ASP 18  19  19  ASP ASP A . n 
A 1 19  ILE 19  20  20  ILE ILE A . n 
A 1 20  GLY 20  21  21  GLY GLY A . n 
A 1 21  ASN 21  22  22  ASN ASN A . n 
A 1 22  TYR 22  23  23  TYR TYR A . n 
A 1 23  TYR 23  24  24  TYR TYR A . n 
A 1 24  TYR 24  25  25  TYR TYR A . n 
A 1 25  GLY 25  26  26  GLY GLY A . n 
A 1 26  GLN 26  27  27  GLN GLN A . n 
A 1 27  GLY 27  28  28  GLY GLY A . n 
A 1 28  HIS 28  29  29  HIS HIS A . n 
A 1 29  PRO 29  30  30  PRO PRO A . n 
A 1 30  MET 30  31  31  MET MET A . n 
A 1 31  LYS 31  32  32  LYS LYS A . n 
A 1 32  PRO 32  33  33  PRO PRO A . n 
A 1 33  HIS 33  34  34  HIS HIS A . n 
A 1 34  ARG 34  35  35  ARG ARG A . n 
A 1 35  ILE 35  36  36  ILE ILE A . n 
A 1 36  ARG 36  37  37  ARG ARG A . n 
A 1 37  MET 37  38  38  MET MET A . n 
A 1 38  THR 38  39  39  THR THR A . n 
A 1 39  HIS 39  40  40  HIS HIS A . n 
A 1 40  ASN 40  41  41  ASN ASN A . n 
A 1 41  LEU 41  42  42  LEU LEU A . n 
A 1 42  LEU 42  43  43  LEU LEU A . n 
A 1 43  LEU 43  44  44  LEU LEU A . n 
A 1 44  ASN 44  45  45  ASN ASN A . n 
A 1 45  TYR 45  46  46  TYR TYR A . n 
A 1 46  GLY 46  47  47  GLY GLY A . n 
A 1 47  LEU 47  48  48  LEU LEU A . n 
A 1 48  TYR 48  49  49  TYR TYR A . n 
A 1 49  ARG 49  50  50  ARG ARG A . n 
A 1 50  LYS 50  51  51  LYS LYS A . n 
A 1 51  MET 51  52  52  MET MET A . n 
A 1 52  GLU 52  53  53  GLU GLU A . n 
A 1 53  ILE 53  54  54  ILE ILE A . n 
A 1 54  TYR 54  55  55  TYR TYR A . n 
A 1 55  ARG 55  56  56  ARG ARG A . n 
A 1 56  PRO 56  57  57  PRO PRO A . n 
A 1 57  HIS 57  58  58  HIS HIS A . n 
A 1 58  LYS 58  59  59  LYS LYS A . n 
A 1 59  ALA 59  60  60  ALA ALA A . n 
A 1 60  THR 60  61  61  THR THR A . n 
A 1 61  ALA 61  62  62  ALA ALA A . n 
A 1 62  GLU 62  63  63  GLU GLU A . n 
A 1 63  GLU 63  64  64  GLU GLU A . n 
A 1 64  MET 64  65  65  MET MET A . n 
A 1 65  THR 65  66  66  THR THR A . n 
A 1 66  LYS 66  67  67  LYS LYS A . n 
A 1 67  TYR 67  68  68  TYR TYR A . n 
A 1 68  HIS 68  69  69  HIS HIS A . n 
A 1 69  SER 69  70  70  SER SER A . n 
A 1 70  ASP 70  71  71  ASP ASP A . n 
A 1 71  GLU 71  72  72  GLU GLU A . n 
A 1 72  TYR 72  73  73  TYR TYR A . n 
A 1 73  ILE 73  74  74  ILE ILE A . n 
A 1 74  LYS 74  75  75  LYS LYS A . n 
A 1 75  PHE 75  76  76  PHE PHE A . n 
A 1 76  LEU 76  77  77  LEU LEU A . n 
A 1 77  ARG 77  78  78  ARG ARG A . n 
A 1 78  SER 78  79  79  SER SER A . n 
A 1 79  ILE 79  80  80  ILE ILE A . n 
A 1 80  ARG 80  81  81  ARG ARG A . n 
A 1 81  PRO 81  82  82  PRO PRO A . n 
A 1 82  ASP 82  83  83  ASP ASP A . n 
A 1 83  ASN 83  84  84  ASN ASN A . n 
A 1 84  MET 84  85  85  MET MET A . n 
A 1 85  SER 85  86  86  SER SER A . n 
A 1 86  GLU 86  87  87  GLU GLU A . n 
A 1 87  TYR 87  88  88  TYR TYR A . n 
A 1 88  SER 88  89  89  SER SER A . n 
A 1 89  LYS 89  90  90  LYS LYS A . n 
A 1 90  GLN 90  91  91  GLN GLN A . n 
A 1 91  MET 91  92  92  MET MET A . n 
A 1 92  GLN 92  93  93  GLN GLN A . n 
A 1 93  ARG 93  94  94  ARG ARG A . n 
A 1 94  PHE 94  95  95  PHE PHE A . n 
A 1 95  ASN 95  96  96  ASN ASN A . n 
A 1 96  VAL 96  97  97  VAL VAL A . n 
A 1 97  GLY 97  98  98  GLY GLY A . n 
A 1 98  GLU 98  99  99  GLU GLU A . n 
A 1 99  ASP 99  100 100 ASP ASP A . n 
A 1 100 CYS 100 101 101 CYS CYS A . n 
A 1 101 PRO 101 102 102 PRO PRO A . n 
A 1 102 VAL 102 103 103 VAL VAL A . n 
A 1 103 PHE 103 104 104 PHE PHE A . n 
A 1 104 ASP 104 105 105 ASP ASP A . n 
A 1 105 GLY 105 106 106 GLY GLY A . n 
A 1 106 LEU 106 107 107 LEU LEU A . n 
A 1 107 PHE 107 108 108 PHE PHE A . n 
A 1 108 GLU 108 109 109 GLU GLU A . n 
A 1 109 PHE 109 110 110 PHE PHE A . n 
A 1 110 CYS 110 111 111 CYS CYS A . n 
A 1 111 GLN 111 112 112 GLN GLN A . n 
A 1 112 LEU 112 113 113 LEU LEU A . n 
A 1 113 SER 113 114 114 SER SER A . n 
A 1 114 THR 114 115 115 THR THR A . n 
A 1 115 GLY 115 116 116 GLY GLY A . n 
A 1 116 GLY 116 117 117 GLY GLY A . n 
A 1 117 SER 117 118 118 SER SER A . n 
A 1 118 VAL 118 119 119 VAL VAL A . n 
A 1 119 ALA 119 120 120 ALA ALA A . n 
A 1 120 GLY 120 121 121 GLY GLY A . n 
A 1 121 ALA 121 122 122 ALA ALA A . n 
A 1 122 VAL 122 123 123 VAL VAL A . n 
A 1 123 LYS 123 124 124 LYS LYS A . n 
A 1 124 LEU 124 125 125 LEU LEU A . n 
A 1 125 ASN 125 126 126 ASN ASN A . n 
A 1 126 ARG 126 127 127 ARG ARG A . n 
A 1 127 GLN 127 128 128 GLN GLN A . n 
A 1 128 GLN 128 129 129 GLN GLN A . n 
A 1 129 THR 129 130 130 THR THR A . n 
A 1 130 ASP 130 131 131 ASP ASP A . n 
A 1 131 MET 131 132 132 MET MET A . n 
A 1 132 ALA 132 133 133 ALA ALA A . n 
A 1 133 VAL 133 134 134 VAL VAL A . n 
A 1 134 ASN 134 135 135 ASN ASN A . n 
A 1 135 TRP 135 136 136 TRP TRP A . n 
A 1 136 ALA 136 137 137 ALA ALA A . n 
A 1 137 GLY 137 138 138 GLY GLY A . n 
A 1 138 GLY 138 139 139 GLY GLY A . n 
A 1 139 LEU 139 140 140 LEU LEU A . n 
A 1 140 HIS 140 141 141 HIS HIS A . n 
A 1 141 HIS 141 142 142 HIS HIS A . n 
A 1 142 ALA 142 143 143 ALA ALA A . n 
A 1 143 LYS 143 144 144 LYS LYS A . n 
A 1 144 LYS 144 145 145 LYS LYS A . n 
A 1 145 SER 145 146 146 SER SER A . n 
A 1 146 GLU 146 147 147 GLU GLU A . n 
A 1 147 ALA 147 148 148 ALA ALA A . n 
A 1 148 SER 148 149 149 SER SER A . n 
A 1 149 GLY 149 150 150 GLY GLY A . n 
A 1 150 PHE 150 151 151 PHE PHE A . n 
A 1 151 CYS 151 152 152 CYS CYS A . n 
A 1 152 TYR 152 153 153 TYR TYR A . n 
A 1 153 VAL 153 154 154 VAL VAL A . n 
A 1 154 ASN 154 155 155 ASN ASN A . n 
A 1 155 ASP 155 156 156 ASP ASP A . n 
A 1 156 ILE 156 157 157 ILE ILE A . n 
A 1 157 VAL 157 158 158 VAL VAL A . n 
A 1 158 LEU 158 159 159 LEU LEU A . n 
A 1 159 ALA 159 160 160 ALA ALA A . n 
A 1 160 ILE 160 161 161 ILE ILE A . n 
A 1 161 LEU 161 162 162 LEU LEU A . n 
A 1 162 GLU 162 163 163 GLU GLU A . n 
A 1 163 LEU 163 164 164 LEU LEU A . n 
A 1 164 LEU 164 165 165 LEU LEU A . n 
A 1 165 LYS 165 166 166 LYS LYS A . n 
A 1 166 TYR 166 167 167 TYR TYR A . n 
A 1 167 HIS 167 168 168 HIS HIS A . n 
A 1 168 GLN 168 169 169 GLN GLN A . n 
A 1 169 ARG 169 170 170 ARG ARG A . n 
A 1 170 VAL 170 171 171 VAL VAL A . n 
A 1 171 LEU 171 172 172 LEU LEU A . n 
A 1 172 TYR 172 173 173 TYR TYR A . n 
A 1 173 ILE 173 174 174 ILE ILE A . n 
A 1 174 ASP 174 175 175 ASP ASP A . n 
A 1 175 ILE 175 176 176 ILE ILE A . n 
A 1 176 ASP 176 177 177 ASP ASP A . n 
A 1 177 ILE 177 178 178 ILE ILE A . n 
A 1 178 HIS 178 179 179 HIS HIS A . n 
A 1 179 HIS 179 180 180 HIS HIS A . n 
A 1 180 GLY 180 181 181 GLY GLY A . n 
A 1 181 ASP 181 182 182 ASP ASP A . n 
A 1 182 GLY 182 183 183 GLY GLY A . n 
A 1 183 VAL 183 184 184 VAL VAL A . n 
A 1 184 GLU 184 185 185 GLU GLU A . n 
A 1 185 GLU 185 186 186 GLU GLU A . n 
A 1 186 ALA 186 187 187 ALA ALA A . n 
A 1 187 PHE 187 188 188 PHE PHE A . n 
A 1 188 TYR 188 189 189 TYR TYR A . n 
A 1 189 THR 189 190 190 THR THR A . n 
A 1 190 THR 190 191 191 THR THR A . n 
A 1 191 ASP 191 192 192 ASP ASP A . n 
A 1 192 ARG 192 193 193 ARG ARG A . n 
A 1 193 VAL 193 194 194 VAL VAL A . n 
A 1 194 MET 194 195 195 MET MET A . n 
A 1 195 THR 195 196 196 THR THR A . n 
A 1 196 VAL 196 197 197 VAL VAL A . n 
A 1 197 SER 197 198 198 SER SER A . n 
A 1 198 PHE 198 199 199 PHE PHE A . n 
A 1 199 HIS 199 200 200 HIS HIS A . n 
A 1 200 LYS 200 201 201 LYS LYS A . n 
A 1 201 TYR 201 202 202 TYR TYR A . n 
A 1 202 GLY 202 203 203 GLY GLY A . n 
A 1 203 GLU 203 204 204 GLU GLU A . n 
A 1 204 TYR 204 205 205 TYR TYR A . n 
A 1 205 PHE 205 206 206 PHE PHE A . n 
A 1 206 PRO 206 207 207 PRO PRO A . n 
A 1 207 GLY 207 208 208 GLY GLY A . n 
A 1 208 THR 208 209 209 THR THR A . n 
A 1 209 GLY 209 210 210 GLY GLY A . n 
A 1 210 ASP 210 211 211 ASP ASP A . n 
A 1 211 LEU 211 212 212 LEU LEU A . n 
A 1 212 ARG 212 213 213 ARG ARG A . n 
A 1 213 ASP 213 214 214 ASP ASP A . n 
A 1 214 ILE 214 215 215 ILE ILE A . n 
A 1 215 GLY 215 216 216 GLY GLY A . n 
A 1 216 ALA 216 217 217 ALA ALA A . n 
A 1 217 GLY 217 218 218 GLY GLY A . n 
A 1 218 LYS 218 219 219 LYS LYS A . n 
A 1 219 GLY 219 220 220 GLY GLY A . n 
A 1 220 LYS 220 221 221 LYS LYS A . n 
A 1 221 TYR 221 222 222 TYR TYR A . n 
A 1 222 TYR 222 223 223 TYR TYR A . n 
A 1 223 ALA 223 224 224 ALA ALA A . n 
A 1 224 VAL 224 225 225 VAL VAL A . n 
A 1 225 ASN 225 226 226 ASN ASN A . n 
A 1 226 PHE 226 227 227 PHE PHE A . n 
A 1 227 PRO 227 228 228 PRO PRO A . n 
A 1 228 MET 228 229 229 MET MET A . n 
A 1 229 ARG 229 230 230 ARG ARG A . n 
A 1 230 ASP 230 231 231 ASP ASP A . n 
A 1 231 GLY 231 232 232 GLY GLY A . n 
A 1 232 ILE 232 233 233 ILE ILE A . n 
A 1 233 ASP 233 234 234 ASP ASP A . n 
A 1 234 ASP 234 235 235 ASP ASP A . n 
A 1 235 GLU 235 236 236 GLU GLU A . n 
A 1 236 SER 236 237 237 SER SER A . n 
A 1 237 TYR 237 238 238 TYR TYR A . n 
A 1 238 GLY 238 239 239 GLY GLY A . n 
A 1 239 GLN 239 240 240 GLN GLN A . n 
A 1 240 ILE 240 241 241 ILE ILE A . n 
A 1 241 PHE 241 242 242 PHE PHE A . n 
A 1 242 LYS 242 243 243 LYS LYS A . n 
A 1 243 PRO 243 244 244 PRO PRO A . n 
A 1 244 ILE 244 245 245 ILE ILE A . n 
A 1 245 ILE 245 246 246 ILE ILE A . n 
A 1 246 SER 246 247 247 SER SER A . n 
A 1 247 LYS 247 248 248 LYS LYS A . n 
A 1 248 VAL 248 249 249 VAL VAL A . n 
A 1 249 MET 249 250 250 MET MET A . n 
A 1 250 GLU 250 251 251 GLU GLU A . n 
A 1 251 MET 251 252 252 MET MET A . n 
A 1 252 TYR 252 253 253 TYR TYR A . n 
A 1 253 GLN 253 254 254 GLN GLN A . n 
A 1 254 PRO 254 255 255 PRO PRO A . n 
A 1 255 SER 255 256 256 SER SER A . n 
A 1 256 ALA 256 257 257 ALA ALA A . n 
A 1 257 VAL 257 258 258 VAL VAL A . n 
A 1 258 VAL 258 259 259 VAL VAL A . n 
A 1 259 LEU 259 260 260 LEU LEU A . n 
A 1 260 GLN 260 261 261 GLN GLN A . n 
A 1 261 CYS 261 262 262 CYS CYS A . n 
A 1 262 GLY 262 263 263 GLY GLY A . n 
A 1 263 ALA 263 264 264 ALA ALA A . n 
A 1 264 ASP 264 265 265 ASP ASP A . n 
A 1 265 SER 265 266 266 SER SER A . n 
A 1 266 LEU 266 267 267 LEU LEU A . n 
A 1 267 SER 267 268 268 SER SER A . n 
A 1 268 GLY 268 269 269 GLY GLY A . n 
A 1 269 ASP 269 270 270 ASP ASP A . n 
A 1 270 ARG 270 271 271 ARG ARG A . n 
A 1 271 LEU 271 272 272 LEU LEU A . n 
A 1 272 GLY 272 273 273 GLY GLY A . n 
A 1 273 CYS 273 274 274 CYS CYS A . n 
A 1 274 PHE 274 275 275 PHE PHE A . n 
A 1 275 ASN 275 276 276 ASN ASN A . n 
A 1 276 LEU 276 277 277 LEU LEU A . n 
A 1 277 THR 277 278 278 THR THR A . n 
A 1 278 VAL 278 279 279 VAL VAL A . n 
A 1 279 LYS 279 280 280 LYS LYS A . n 
A 1 280 GLY 280 281 281 GLY GLY A . n 
A 1 281 HIS 281 282 282 HIS HIS A . n 
A 1 282 ALA 282 283 283 ALA ALA A . n 
A 1 283 LYS 283 284 284 LYS LYS A . n 
A 1 284 CYS 284 285 285 CYS CYS A . n 
A 1 285 VAL 285 286 286 VAL VAL A . n 
A 1 286 GLU 286 287 287 GLU GLU A . n 
A 1 287 VAL 287 288 288 VAL VAL A . n 
A 1 288 VAL 288 289 289 VAL VAL A . n 
A 1 289 LYS 289 290 290 LYS LYS A . n 
A 1 290 THR 290 291 291 THR THR A . n 
A 1 291 PHE 291 292 292 PHE PHE A . n 
A 1 292 ASN 292 293 293 ASN ASN A . n 
A 1 293 LEU 293 294 294 LEU LEU A . n 
A 1 294 PRO 294 295 295 PRO PRO A . n 
A 1 295 LEU 295 296 296 LEU LEU A . n 
A 1 296 LEU 296 297 297 LEU LEU A . n 
A 1 297 MET 297 298 298 MET MET A . n 
A 1 298 LEU 298 299 299 LEU LEU A . n 
A 1 299 GLY 299 300 300 GLY GLY A . n 
A 1 300 GLY 300 301 301 GLY GLY A . n 
A 1 301 GLY 301 302 302 GLY GLY A . n 
A 1 302 GLY 302 303 303 GLY GLY A . n 
A 1 303 TYR 303 304 304 TYR TYR A . n 
A 1 304 THR 304 305 305 THR THR A . n 
A 1 305 ILE 305 306 306 ILE ILE A . n 
A 1 306 ARG 306 307 307 ARG ARG A . n 
A 1 307 ASN 307 308 308 ASN ASN A . n 
A 1 308 VAL 308 309 309 VAL VAL A . n 
A 1 309 ALA 309 310 310 ALA ALA A . n 
A 1 310 ARG 310 311 311 ARG ARG A . n 
A 1 311 CYS 311 312 312 CYS CYS A . n 
A 1 312 TRP 312 313 313 TRP TRP A . n 
A 1 313 THR 313 314 314 THR THR A . n 
A 1 314 TYR 314 315 315 TYR TYR A . n 
A 1 315 GLU 315 316 316 GLU GLU A . n 
A 1 316 THR 316 317 317 THR THR A . n 
A 1 317 ALA 317 318 318 ALA ALA A . n 
A 1 318 VAL 318 319 319 VAL VAL A . n 
A 1 319 ALA 319 320 320 ALA ALA A . n 
A 1 320 LEU 320 321 321 LEU LEU A . n 
A 1 321 ASP 321 322 322 ASP ASP A . n 
A 1 322 CYS 322 323 323 CYS CYS A . n 
A 1 323 GLU 323 324 324 GLU GLU A . n 
A 1 324 ILE 324 325 325 ILE ILE A . n 
A 1 325 PRO 325 326 326 PRO PRO A . n 
A 1 326 ASN 326 327 327 ASN ASN A . n 
A 1 327 GLU 327 328 328 GLU GLU A . n 
A 1 328 LEU 328 329 329 LEU LEU A . n 
A 1 329 PRO 329 330 330 PRO PRO A . n 
A 1 330 TYR 330 331 331 TYR TYR A . n 
A 1 331 ASN 331 332 332 ASN ASN A . n 
A 1 332 ASP 332 333 333 ASP ASP A . n 
A 1 333 TYR 333 334 334 TYR TYR A . n 
A 1 334 PHE 334 335 335 PHE PHE A . n 
A 1 335 GLU 335 336 336 GLU GLU A . n 
A 1 336 TYR 336 337 337 TYR TYR A . n 
A 1 337 PHE 337 338 338 PHE PHE A . n 
A 1 338 GLY 338 339 339 GLY GLY A . n 
A 1 339 PRO 339 340 340 PRO PRO A . n 
A 1 340 ASP 340 341 341 ASP ASP A . n 
A 1 341 PHE 341 342 342 PHE PHE A . n 
A 1 342 LYS 342 343 343 LYS LYS A . n 
A 1 343 LEU 343 344 344 LEU LEU A . n 
A 1 344 HIS 344 345 345 HIS HIS A . n 
A 1 345 ILE 345 346 346 ILE ILE A . n 
A 1 346 SER 346 347 347 SER SER A . n 
A 1 347 PRO 347 348 348 PRO PRO A . n 
A 1 348 SER 348 349 349 SER SER A . n 
A 1 349 ASN 349 350 350 ASN ASN A . n 
A 1 350 MET 350 351 351 MET MET A . n 
A 1 351 THR 351 352 352 THR THR A . n 
A 1 352 ASN 352 353 353 ASN ASN A . n 
A 1 353 GLN 353 354 354 GLN GLN A . n 
A 1 354 ASN 354 355 355 ASN ASN A . n 
A 1 355 THR 355 356 356 THR THR A . n 
A 1 356 PRO 356 357 357 PRO PRO A . n 
A 1 357 GLU 357 358 358 GLU GLU A . n 
A 1 358 TYR 358 359 359 TYR TYR A . n 
A 1 359 MET 359 360 360 MET MET A . n 
A 1 360 GLU 360 361 361 GLU GLU A . n 
A 1 361 LYS 361 362 362 LYS LYS A . n 
A 1 362 ILE 362 363 363 ILE ILE A . n 
A 1 363 LYS 363 364 364 LYS LYS A . n 
A 1 364 GLN 364 365 365 GLN GLN A . n 
A 1 365 ARG 365 366 366 ARG ARG A . n 
A 1 366 LEU 366 367 367 LEU LEU A . n 
A 1 367 PHE 367 368 368 PHE PHE A . n 
A 1 368 GLU 368 369 369 GLU GLU A . n 
A 1 369 ASN 369 370 370 ASN ASN A . n 
A 1 370 LEU 370 371 371 LEU LEU A . n 
A 1 371 ARG 371 372 372 ARG ARG A . n 
A 1 372 MET 372 373 373 MET MET A . n 
A 1 373 LEU 373 374 374 LEU LEU A . n 
A 1 374 PRO 374 375 375 PRO PRO A . n 
A 1 375 HIS 375 376 ?   ?   ?   A . n 
A 1 376 ALA 376 377 ?   ?   ?   A . n 
A 1 377 PRO 377 378 ?   ?   ?   A . n 
A 1 378 GLY 378 379 ?   ?   ?   A . n 
A 1 379 VAL 379 380 ?   ?   ?   A . n 
A 1 380 GLN 380 381 ?   ?   ?   A . n 
A 1 381 MET 381 382 ?   ?   ?   A . n 
A 1 382 GLN 382 383 ?   ?   ?   A . n 
A 1 383 ALA 383 384 ?   ?   ?   A . n 
A 1 384 ILE 384 385 ?   ?   ?   A . n 
A 1 385 PRO 385 386 ?   ?   ?   A . n 
A 1 386 GLU 386 387 ?   ?   ?   A . n 
A 1 387 ASP 387 388 ?   ?   ?   A . n 
A 1 388 ALA 388 389 ?   ?   ?   A . n 
A 1 389 VAL 389 390 ?   ?   ?   A . n 
A 1 390 HIS 390 391 ?   ?   ?   A . n 
A 1 391 GLU 391 392 ?   ?   ?   A . n 
A 1 392 ASP 392 393 ?   ?   ?   A . n 
A 1 393 SER 393 394 ?   ?   ?   A . n 
A 1 394 GLY 394 395 ?   ?   ?   A . n 
A 1 395 ASP 395 396 ?   ?   ?   A . n 
A 1 396 GLU 396 397 ?   ?   ?   A . n 
A 1 397 ASP 397 398 ?   ?   ?   A . n 
A 1 398 GLY 398 399 ?   ?   ?   A . n 
A 1 399 GLU 399 400 ?   ?   ?   A . n 
A 1 400 ASP 400 401 ?   ?   ?   A . n 
A 1 401 PRO 401 402 ?   ?   ?   A . n 
A 1 402 ASP 402 403 ?   ?   ?   A . n 
A 1 403 LYS 403 404 ?   ?   ?   A . n 
A 1 404 ARG 404 405 ?   ?   ?   A . n 
A 1 405 ILE 405 406 ?   ?   ?   A . n 
A 1 406 SER 406 407 ?   ?   ?   A . n 
A 1 407 ILE 407 408 ?   ?   ?   A . n 
A 1 408 ARG 408 409 ?   ?   ?   A . n 
A 1 409 ALA 409 410 ?   ?   ?   A . n 
A 1 410 SER 410 411 ?   ?   ?   A . n 
A 1 411 ASP 411 412 ?   ?   ?   A . n 
A 1 412 LYS 412 413 ?   ?   ?   A . n 
A 1 413 ARG 413 414 ?   ?   ?   A . n 
A 1 414 ILE 414 415 ?   ?   ?   A . n 
A 1 415 ALA 415 416 ?   ?   ?   A . n 
A 1 416 CYS 416 417 ?   ?   ?   A . n 
A 1 417 ASP 417 418 ?   ?   ?   A . n 
A 1 418 GLU 418 419 ?   ?   ?   A . n 
A 1 419 GLU 419 420 ?   ?   ?   A . n 
A 1 420 PHE 420 421 ?   ?   ?   A . n 
A 1 421 SER 421 422 ?   ?   ?   A . n 
A 1 422 ASP 422 423 ?   ?   ?   A . n 
A 1 423 SER 423 424 ?   ?   ?   A . n 
A 1 424 GLU 424 425 ?   ?   ?   A . n 
A 1 425 ASP 425 426 ?   ?   ?   A . n 
A 1 426 GLU 426 427 ?   ?   ?   A . n 
A 1 427 GLY 427 428 ?   ?   ?   A . n 
A 1 428 GLU 428 429 ?   ?   ?   A . n 
A 1 429 GLY 429 430 ?   ?   ?   A . n 
A 1 430 GLY 430 431 ?   ?   ?   A . n 
A 1 431 ARG 431 432 ?   ?   ?   A . n 
A 1 432 ARG 432 433 ?   ?   ?   A . n 
A 1 433 ASN 433 434 ?   ?   ?   A . n 
A 1 434 VAL 434 435 ?   ?   ?   A . n 
A 1 435 ALA 435 436 ?   ?   ?   A . n 
A 1 436 ASP 436 437 ?   ?   ?   A . n 
A 1 437 HIS 437 438 ?   ?   ?   A . n 
A 1 438 LYS 438 439 ?   ?   ?   A . n 
A 1 439 LYS 439 440 ?   ?   ?   A . n 
A 1 440 GLY 440 441 ?   ?   ?   A . n 
A 1 441 ALA 441 442 ?   ?   ?   A . n 
A 1 442 LYS 442 443 ?   ?   ?   A . n 
A 1 443 LYS 443 444 ?   ?   ?   A . n 
A 1 444 ALA 444 445 ?   ?   ?   A . n 
A 1 445 ARG 445 446 ?   ?   ?   A . n 
A 1 446 ILE 446 447 ?   ?   ?   A . n 
A 1 447 GLU 447 448 ?   ?   ?   A . n 
A 1 448 GLU 448 449 ?   ?   ?   A . n 
A 1 449 ASP 449 450 ?   ?   ?   A . n 
A 1 450 LYS 450 451 ?   ?   ?   A . n 
A 1 451 LYS 451 452 ?   ?   ?   A . n 
A 1 452 GLU 452 453 ?   ?   ?   A . n 
A 1 453 THR 453 454 ?   ?   ?   A . n 
A 1 454 GLU 454 455 ?   ?   ?   A . n 
A 1 455 ASP 455 456 ?   ?   ?   A . n 
A 1 456 LYS 456 457 ?   ?   ?   A . n 
A 1 457 LYS 457 458 ?   ?   ?   A . n 
A 1 458 THR 458 459 ?   ?   ?   A . n 
A 1 459 ASP 459 460 ?   ?   ?   A . n 
A 1 460 VAL 460 461 ?   ?   ?   A . n 
A 1 461 LYS 461 462 ?   ?   ?   A . n 
A 1 462 GLU 462 463 ?   ?   ?   A . n 
A 1 463 GLU 463 464 ?   ?   ?   A . n 
A 1 464 ASP 464 465 ?   ?   ?   A . n 
A 1 465 LYS 465 466 ?   ?   ?   A . n 
A 1 466 SER 466 467 ?   ?   ?   A . n 
A 1 467 LYS 467 468 ?   ?   ?   A . n 
A 1 468 ASP 468 469 ?   ?   ?   A . n 
A 1 469 ASN 469 470 ?   ?   ?   A . n 
A 1 470 SER 470 471 ?   ?   ?   A . n 
A 1 471 GLY 471 472 ?   ?   ?   A . n 
A 1 472 GLU 472 473 ?   ?   ?   A . n 
A 1 473 LYS 473 474 ?   ?   ?   A . n 
A 1 474 THR 474 475 ?   ?   ?   A . n 
A 1 475 ASP 475 476 ?   ?   ?   A . n 
A 1 476 THR 476 477 ?   ?   ?   A . n 
A 1 477 LYS 477 478 ?   ?   ?   A . n 
A 1 478 GLY 478 479 ?   ?   ?   A . n 
A 1 479 THR 479 480 ?   ?   ?   A . n 
A 1 480 LYS 480 481 ?   ?   ?   A . n 
A 1 481 SER 481 482 ?   ?   ?   A . n 
A 1 482 GLU 482 483 ?   ?   ?   A . n 
A 1 483 GLN 483 484 ?   ?   ?   A . n 
A 1 484 LEU 484 485 ?   ?   ?   A . n 
A 1 485 SER 485 486 ?   ?   ?   A . n 
A 1 486 ASN 486 487 ?   ?   ?   A . n 
A 1 487 PRO 487 488 ?   ?   ?   A . n 
B 2 1   MET 1   17  ?   ?   ?   B . n 
B 2 2   GLU 2   18  ?   ?   ?   B . n 
B 2 3   SER 3   19  ?   ?   ?   B . n 
B 2 4   PRO 4   20  ?   ?   ?   B . n 
B 2 5   GLU 5   21  ?   ?   ?   B . n 
B 2 6   GLU 6   22  ?   ?   ?   B . n 
B 2 7   PRO 7   23  ?   ?   ?   B . n 
B 2 8   GLY 8   24  ?   ?   ?   B . n 
B 2 9   ALA 9   25  ?   ?   ?   B . n 
B 2 10  SER 10  26  26  SER SER B . n 
B 2 11  MET 11  27  27  MET MET B . n 
B 2 12  ASP 12  28  28  ASP ASP B . n 
B 2 13  GLU 13  29  29  GLU GLU B . n 
B 2 14  ASN 14  30  30  ASN ASN B . n 
B 2 15  TYR 15  31  31  TYR TYR B . n 
B 2 16  PHE 16  32  32  PHE PHE B . n 
B 2 17  VAL 17  33  33  VAL VAL B . n 
B 2 18  ASN 18  34  34  ASN ASN B . n 
B 2 19  TYR 19  35  35  TYR TYR B . n 
B 2 20  THR 20  36  36  THR THR B . n 
B 2 21  PHE 21  37  37  PHE PHE B . n 
B 2 22  LYS 22  38  38  LYS LYS B . n 
B 2 23  ASP 23  39  39  ASP ASP B . n 
B 2 24  ARG 24  40  40  ARG ARG B . n 
B 2 25  SER 25  41  41  SER SER B . n 
B 2 26  HIS 26  42  42  HIS HIS B . n 
B 2 27  SER 27  43  43  SER SER B . n 
B 2 28  GLY 28  44  44  GLY GLY B . n 
B 2 29  ARG 29  45  45  ARG ARG B . n 
B 2 30  VAL 30  46  46  VAL VAL B . n 
B 2 31  ALA 31  47  47  ALA ALA B . n 
B 2 32  GLN 32  48  48  GLN GLN B . n 
B 2 33  GLY 33  49  49  GLY GLY B . n 
B 2 34  ILE 34  50  50  ILE ILE B . n 
B 2 35  MET 35  51  51  MET MET B . n 
B 2 36  LYS 36  52  52  LYS LYS B . n 
B 2 37  LEU 37  53  53  LEU LEU B . n 
B 2 38  CYS 38  54  54  CYS CYS B . n 
B 2 39  LEU 39  55  55  LEU LEU B . n 
B 2 40  GLU 40  56  56  GLU GLU B . n 
B 2 41  GLU 41  57  57  GLU GLU B . n 
B 2 42  GLU 42  58  58  GLU GLU B . n 
B 2 43  LEU 43  59  59  LEU LEU B . n 
B 2 44  PHE 44  60  60  PHE PHE B . n 
B 2 45  ALA 45  61  61  ALA ALA B . n 
B 2 46  ASP 46  62  62  ASP ASP B . n 
B 2 47  VAL 47  63  63  VAL VAL B . n 
B 2 48  THR 48  64  64  THR THR B . n 
B 2 49  ILE 49  65  65  ILE ILE B . n 
B 2 50  SER 50  66  66  SER SER B . n 
B 2 51  VAL 51  67  67  VAL VAL B . n 
B 2 52  GLU 52  68  68  GLU GLU B . n 
B 2 53  GLY 53  69  69  GLY GLY B . n 
B 2 54  ARG 54  70  70  ARG ARG B . n 
B 2 55  GLU 55  71  71  GLU GLU B . n 
B 2 56  PHE 56  72  72  PHE PHE B . n 
B 2 57  GLN 57  73  73  GLN GLN B . n 
B 2 58  LEU 58  74  74  LEU LEU B . n 
B 2 59  HIS 59  75  75  HIS HIS B . n 
B 2 60  ARG 60  76  76  ARG ARG B . n 
B 2 61  LEU 61  77  77  LEU LEU B . n 
B 2 62  VAL 62  78  78  VAL VAL B . n 
B 2 63  LEU 63  79  79  LEU LEU B . n 
B 2 64  SER 64  80  80  SER SER B . n 
B 2 65  ALA 65  81  81  ALA ALA B . n 
B 2 66  GLN 66  82  82  GLN GLN B . n 
B 2 67  SER 67  83  83  SER SER B . n 
B 2 68  CYS 68  84  84  CYS CYS B . n 
B 2 69  PHE 69  85  85  PHE PHE B . n 
B 2 70  PHE 70  86  86  PHE PHE B . n 
B 2 71  ARG 71  87  87  ARG ARG B . n 
B 2 72  SER 72  88  88  SER SER B . n 
B 2 73  MET 73  89  89  MET MET B . n 
B 2 74  PHE 74  90  90  PHE PHE B . n 
B 2 75  THR 75  91  91  THR THR B . n 
B 2 76  SER 76  92  92  SER SER B . n 
B 2 77  ASN 77  93  93  ASN ASN B . n 
B 2 78  LEU 78  94  94  LEU LEU B . n 
B 2 79  LYS 79  95  95  LYS LYS B . n 
B 2 80  GLU 80  96  96  GLU GLU B . n 
B 2 81  ALA 81  97  97  ALA ALA B . n 
B 2 82  HIS 82  98  98  HIS HIS B . n 
B 2 83  ASN 83  99  99  ASN ASN B . n 
B 2 84  ARG 84  100 100 ARG ARG B . n 
B 2 85  VAL 85  101 101 VAL VAL B . n 
B 2 86  ILE 86  102 102 ILE ILE B . n 
B 2 87  VAL 87  103 103 VAL VAL B . n 
B 2 88  LEU 88  104 104 LEU LEU B . n 
B 2 89  GLN 89  105 105 GLN GLN B . n 
B 2 90  ASP 90  106 106 ASP ASP B . n 
B 2 91  VAL 91  107 107 VAL VAL B . n 
B 2 92  SER 92  108 108 SER SER B . n 
B 2 93  GLU 93  109 109 GLU GLU B . n 
B 2 94  SER 94  110 110 SER SER B . n 
B 2 95  VAL 95  111 111 VAL VAL B . n 
B 2 96  PHE 96  112 112 PHE PHE B . n 
B 2 97  GLN 97  113 113 GLN GLN B . n 
B 2 98  LEU 98  114 114 LEU LEU B . n 
B 2 99  LEU 99  115 115 LEU LEU B . n 
B 2 100 VAL 100 116 116 VAL VAL B . n 
B 2 101 ASP 101 117 117 ASP ASP B . n 
B 2 102 TYR 102 118 118 TYR TYR B . n 
B 2 103 ILE 103 119 119 ILE ILE B . n 
B 2 104 TYR 104 120 120 TYR TYR B . n 
B 2 105 HIS 105 121 121 HIS HIS B . n 
B 2 106 GLY 106 122 122 GLY GLY B . n 
B 2 107 THR 107 123 123 THR THR B . n 
B 2 108 VAL 108 124 124 VAL VAL B . n 
B 2 109 LYS 109 125 125 LYS LYS B . n 
B 2 110 LEU 110 126 126 LEU LEU B . n 
B 2 111 ARG 111 127 127 ARG ARG B . n 
B 2 112 ALA 112 128 128 ALA ALA B . n 
B 2 113 GLU 113 129 129 GLU GLU B . n 
B 2 114 GLU 114 130 130 GLU GLU B . n 
B 2 115 LEU 115 131 131 LEU LEU B . n 
B 2 116 GLN 116 132 132 GLN GLN B . n 
B 2 117 GLU 117 133 133 GLU GLU B . n 
B 2 118 ILE 118 134 134 ILE ILE B . n 
B 2 119 TYR 119 135 135 TYR TYR B . n 
B 2 120 GLU 120 136 136 GLU GLU B . n 
B 2 121 VAL 121 137 137 VAL VAL B . n 
B 2 122 SER 122 138 138 SER SER B . n 
B 2 123 ASP 123 139 139 ASP ASP B . n 
B 2 124 MET 124 140 140 MET MET B . n 
B 2 125 TYR 125 141 141 TYR TYR B . n 
B 2 126 GLN 126 142 142 GLN GLN B . n 
B 2 127 LEU 127 143 143 LEU LEU B . n 
B 2 128 THR 128 144 144 THR THR B . n 
B 2 129 SER 129 145 145 SER SER B . n 
B 2 130 LEU 130 146 146 LEU LEU B . n 
B 2 131 PHE 131 147 147 PHE PHE B . n 
B 2 132 GLU 132 148 148 GLU GLU B . n 
B 2 133 GLU 133 149 149 GLU GLU B . n 
B 2 134 CYS 134 150 150 CYS CYS B . n 
B 2 135 SER 135 151 151 SER SER B . n 
B 2 136 ARG 136 152 152 ARG ARG B . n 
B 2 137 PHE 137 153 153 PHE PHE B . n 
B 2 138 LEU 138 154 154 LEU LEU B . n 
B 2 139 ALA 139 155 155 ALA ALA B . n 
B 2 140 ARG 140 156 156 ARG ARG B . n 
B 2 141 THR 141 157 157 THR THR B . n 
B 2 142 VAL 142 158 158 VAL VAL B . n 
B 2 143 GLN 143 159 159 GLN GLN B . n 
B 2 144 VAL 144 160 160 VAL VAL B . n 
B 2 145 GLY 145 161 161 GLY GLY B . n 
B 2 146 ASN 146 162 162 ASN ASN B . n 
B 2 147 CYS 147 163 163 CYS CYS B . n 
B 2 148 LEU 148 164 164 LEU LEU B . n 
B 2 149 GLN 149 165 165 GLN GLN B . n 
B 2 150 VAL 150 166 166 VAL VAL B . n 
B 2 151 MET 151 167 167 MET MET B . n 
B 2 152 TRP 152 168 168 TRP TRP B . n 
B 2 153 LEU 153 169 169 LEU LEU B . n 
B 2 154 ALA 154 170 170 ALA ALA B . n 
B 2 155 ASP 155 171 171 ASP ASP B . n 
B 2 156 ARG 156 172 172 ARG ARG B . n 
B 2 157 HIS 157 173 173 HIS HIS B . n 
B 2 158 SER 158 174 174 SER SER B . n 
B 2 159 ASP 159 175 175 ASP ASP B . n 
B 2 160 PRO 160 176 176 PRO PRO B . n 
B 2 161 GLU 161 177 177 GLU GLU B . n 
B 2 162 LEU 162 178 178 LEU LEU B . n 
B 2 163 TYR 163 179 179 TYR TYR B . n 
B 2 164 THR 164 180 180 THR THR B . n 
B 2 165 ALA 165 181 181 ALA ALA B . n 
B 2 166 ALA 166 182 182 ALA ALA B . n 
B 2 167 LYS 167 183 183 LYS LYS B . n 
B 2 168 HIS 168 184 184 HIS HIS B . n 
B 2 169 CYS 169 185 185 CYS CYS B . n 
B 2 170 ALA 170 186 186 ALA ALA B . n 
B 2 171 LYS 171 187 187 LYS LYS B . n 
B 2 172 THR 172 188 188 THR THR B . n 
B 2 173 HIS 173 189 189 HIS HIS B . n 
B 2 174 LEU 174 190 190 LEU LEU B . n 
B 2 175 ALA 175 191 191 ALA ALA B . n 
B 2 176 GLN 176 192 192 GLN GLN B . n 
B 2 177 LEU 177 193 193 LEU LEU B . n 
B 2 178 GLN 178 194 194 GLN GLN B . n 
B 2 179 ASN 179 195 195 ASN ASN B . n 
B 2 180 THR 180 196 196 THR THR B . n 
B 2 181 GLU 181 197 197 GLU GLU B . n 
B 2 182 GLU 182 198 198 GLU GLU B . n 
B 2 183 PHE 183 199 199 PHE PHE B . n 
B 2 184 LEU 184 200 200 LEU LEU B . n 
B 2 185 HIS 185 201 201 HIS HIS B . n 
B 2 186 LEU 186 202 202 LEU LEU B . n 
B 2 187 PRO 187 203 203 PRO PRO B . n 
B 2 188 HIS 188 204 204 HIS HIS B . n 
B 2 189 ARG 189 205 205 ARG ARG B . n 
B 2 190 LEU 190 206 206 LEU LEU B . n 
B 2 191 LEU 191 207 207 LEU LEU B . n 
B 2 192 THR 192 208 208 THR THR B . n 
B 2 193 ASP 193 209 209 ASP ASP B . n 
B 2 194 ILE 194 210 210 ILE ILE B . n 
B 2 195 ILE 195 211 211 ILE ILE B . n 
B 2 196 SER 196 212 212 SER SER B . n 
B 2 197 ASP 197 213 213 ASP ASP B . n 
B 2 198 GLY 198 214 214 GLY GLY B . n 
B 2 199 VAL 199 215 215 VAL VAL B . n 
B 2 200 PRO 200 216 216 PRO PRO B . n 
B 2 201 CYS 201 217 217 CYS CYS B . n 
B 2 202 SER 202 218 218 SER SER B . n 
B 2 203 GLN 203 219 219 GLN GLN B . n 
B 2 204 ASN 204 220 220 ASN ASN B . n 
B 2 205 PRO 205 221 221 PRO PRO B . n 
B 2 206 THR 206 222 222 THR THR B . n 
B 2 207 GLU 207 223 223 GLU GLU B . n 
B 2 208 ALA 208 224 224 ALA ALA B . n 
B 2 209 ILE 209 225 225 ILE ILE B . n 
B 2 210 GLU 210 226 226 GLU GLU B . n 
B 2 211 ALA 211 227 227 ALA ALA B . n 
B 2 212 TRP 212 228 228 TRP TRP B . n 
B 2 213 ILE 213 229 229 ILE ILE B . n 
B 2 214 ASN 214 230 230 ASN ASN B . n 
B 2 215 PHE 215 231 231 PHE PHE B . n 
B 2 216 ASN 216 232 232 ASN ASN B . n 
B 2 217 LYS 217 233 233 LYS LYS B . n 
B 2 218 GLU 218 234 234 GLU GLU B . n 
B 2 219 GLU 219 235 235 GLU GLU B . n 
B 2 220 ARG 220 236 236 ARG ARG B . n 
B 2 221 GLU 221 237 237 GLU GLU B . n 
B 2 222 ALA 222 238 238 ALA ALA B . n 
B 2 223 PHE 223 239 239 PHE PHE B . n 
B 2 224 ALA 224 240 240 ALA ALA B . n 
B 2 225 GLU 225 241 241 GLU GLU B . n 
B 2 226 SER 226 242 242 SER SER B . n 
B 2 227 LEU 227 243 243 LEU LEU B . n 
B 2 228 ARG 228 244 244 ARG ARG B . n 
B 2 229 THR 229 245 245 THR THR B . n 
B 2 230 SER 230 246 246 SER SER B . n 
B 2 231 LEU 231 247 247 LEU LEU B . n 
B 2 232 LYS 232 248 248 LYS LYS B . n 
B 2 233 GLU 233 249 249 GLU GLU B . n 
B 2 234 ILE 234 250 250 ILE ILE B . n 
B 2 235 GLY 235 251 251 GLY GLY B . n 
B 2 236 GLU 236 252 252 GLU GLU B . n 
B 2 237 ASN 237 253 253 ASN ASN B . n 
B 2 238 VAL 238 254 254 VAL VAL B . n 
B 2 239 HIS 239 255 255 HIS HIS B . n 
B 2 240 ILE 240 256 256 ILE ILE B . n 
B 2 241 TYR 241 257 257 TYR TYR B . n 
B 2 242 LEU 242 258 258 LEU LEU B . n 
B 2 243 ILE 243 259 259 ILE ILE B . n 
B 2 244 GLY 244 260 260 GLY GLY B . n 
B 2 245 LYS 245 261 261 LYS LYS B . n 
B 2 246 GLU 246 262 262 GLU GLU B . n 
B 2 247 SER 247 263 263 SER SER B . n 
B 2 248 SER 248 264 264 SER SER B . n 
B 2 249 ARG 249 265 265 ARG ARG B . n 
B 2 250 THR 250 266 266 THR THR B . n 
B 2 251 HIS 251 267 267 HIS HIS B . n 
B 2 252 SER 252 268 268 SER SER B . n 
B 2 253 LEU 253 269 269 LEU LEU B . n 
B 2 254 ALA 254 270 270 ALA ALA B . n 
B 2 255 VAL 255 271 271 VAL VAL B . n 
B 2 256 SER 256 272 272 SER SER B . n 
B 2 257 LEU 257 273 273 LEU LEU B . n 
B 2 258 HIS 258 274 274 HIS HIS B . n 
B 2 259 CYS 259 275 275 CYS CYS B . n 
B 2 260 ALA 260 276 276 ALA ALA B . n 
B 2 261 GLU 261 277 277 GLU GLU B . n 
B 2 262 ASP 262 278 278 ASP ASP B . n 
B 2 263 ASP 263 279 279 ASP ASP B . n 
B 2 264 SER 264 280 280 SER SER B . n 
B 2 265 ILE 265 281 281 ILE ILE B . n 
B 2 266 SER 266 282 282 SER SER B . n 
B 2 267 VAL 267 283 283 VAL VAL B . n 
B 2 268 SER 268 284 284 SER SER B . n 
B 2 269 GLY 269 285 285 GLY GLY B . n 
B 2 270 GLN 270 286 286 GLN GLN B . n 
B 2 271 ASN 271 287 287 ASN ASN B . n 
B 2 272 SER 272 288 288 SER SER B . n 
B 2 273 LEU 273 289 289 LEU LEU B . n 
B 2 274 CYS 274 290 290 CYS CYS B . n 
B 2 275 HIS 275 291 291 HIS HIS B . n 
B 2 276 GLN 276 292 292 GLN GLN B . n 
B 2 277 ILE 277 293 293 ILE ILE B . n 
B 2 278 THR 278 294 294 THR THR B . n 
B 2 279 ALA 279 295 295 ALA ALA B . n 
B 2 280 ALA 280 296 296 ALA ALA B . n 
B 2 281 CYS 281 297 297 CYS CYS B . n 
B 2 282 LYS 282 298 298 LYS LYS B . n 
B 2 283 HIS 283 299 299 HIS HIS B . n 
B 2 284 GLY 284 300 300 GLY GLY B . n 
B 2 285 GLY 285 301 301 GLY GLY B . n 
B 2 286 ASP 286 302 302 ASP ASP B . n 
B 2 287 LEU 287 303 303 LEU LEU B . n 
B 2 288 TYR 288 304 304 TYR TYR B . n 
B 2 289 VAL 289 305 305 VAL VAL B . n 
B 2 290 VAL 290 306 306 VAL VAL B . n 
B 2 291 GLY 291 307 307 GLY GLY B . n 
B 2 292 GLY 292 308 308 GLY GLY B . n 
B 2 293 SER 293 309 309 SER SER B . n 
B 2 294 ILE 294 310 310 ILE ILE B . n 
B 2 295 PRO 295 311 311 PRO PRO B . n 
B 2 296 ARG 296 312 312 ARG ARG B . n 
B 2 297 PRO 297 313 313 PRO PRO B . n 
B 2 298 ARG 298 314 314 ARG ARG B . n 
B 2 299 ARG 299 315 315 ARG ARG B . n 
B 2 300 MET 300 316 316 MET MET B . n 
B 2 301 TRP 301 317 317 TRP TRP B . n 
B 2 302 LYS 302 318 318 LYS LYS B . n 
B 2 303 CYS 303 319 319 CYS CYS B . n 
B 2 304 ASN 304 320 320 ASN ASN B . n 
B 2 305 ASN 305 321 321 ASN ASN B . n 
B 2 306 ALA 306 322 322 ALA ALA B . n 
B 2 307 THR 307 323 323 THR THR B . n 
B 2 308 VAL 308 324 324 VAL VAL B . n 
B 2 309 ASP 309 325 325 ASP ASP B . n 
B 2 310 TRP 310 326 326 TRP TRP B . n 
B 2 311 GLU 311 327 327 GLU GLU B . n 
B 2 312 TRP 312 328 328 TRP TRP B . n 
B 2 313 CYS 313 329 329 CYS CYS B . n 
B 2 314 ALA 314 330 330 ALA ALA B . n 
B 2 315 PRO 315 331 331 PRO PRO B . n 
B 2 316 LEU 316 332 332 LEU LEU B . n 
B 2 317 PRO 317 333 333 PRO PRO B . n 
B 2 318 ARG 318 334 334 ARG ARG B . n 
B 2 319 ASP 319 335 335 ASP ASP B . n 
B 2 320 ARG 320 336 336 ARG ARG B . n 
B 2 321 LEU 321 337 337 LEU LEU B . n 
B 2 322 GLN 322 338 338 GLN GLN B . n 
B 2 323 HIS 323 339 339 HIS HIS B . n 
B 2 324 THR 324 340 340 THR THR B . n 
B 2 325 LEU 325 341 341 LEU LEU B . n 
B 2 326 VAL 326 342 342 VAL VAL B . n 
B 2 327 SER 327 343 343 SER SER B . n 
B 2 328 VAL 328 344 344 VAL VAL B . n 
B 2 329 PRO 329 345 345 PRO PRO B . n 
B 2 330 GLY 330 346 346 GLY GLY B . n 
B 2 331 LYS 331 347 347 LYS LYS B . n 
B 2 332 ASP 332 348 348 ASP ASP B . n 
B 2 333 ALA 333 349 349 ALA ALA B . n 
B 2 334 ILE 334 350 350 ILE ILE B . n 
B 2 335 TYR 335 351 351 TYR TYR B . n 
B 2 336 SER 336 352 352 SER SER B . n 
B 2 337 LEU 337 353 353 LEU LEU B . n 
B 2 338 GLY 338 354 354 GLY GLY B . n 
B 2 339 GLY 339 355 355 GLY GLY B . n 
B 2 340 LYS 340 356 356 LYS LYS B . n 
B 2 341 THR 341 357 357 THR THR B . n 
B 2 342 LEU 342 358 358 LEU LEU B . n 
B 2 343 GLN 343 359 359 GLN GLN B . n 
B 2 344 ASP 344 360 360 ASP ASP B . n 
B 2 345 THR 345 361 361 THR THR B . n 
B 2 346 LEU 346 362 362 LEU LEU B . n 
B 2 347 SER 347 363 363 SER SER B . n 
B 2 348 ASN 348 364 364 ASN ASN B . n 
B 2 349 ALA 349 365 365 ALA ALA B . n 
B 2 350 VAL 350 366 366 VAL VAL B . n 
B 2 351 ILE 351 367 367 ILE ILE B . n 
B 2 352 TYR 352 368 368 TYR TYR B . n 
B 2 353 TYR 353 369 369 TYR TYR B . n 
B 2 354 ARG 354 370 370 ARG ARG B . n 
B 2 355 VAL 355 371 371 VAL VAL B . n 
B 2 356 GLY 356 372 372 GLY GLY B . n 
B 2 357 ASP 357 373 373 ASP ASP B . n 
B 2 358 ASN 358 374 374 ASN ASN B . n 
B 2 359 VAL 359 375 375 VAL VAL B . n 
B 2 360 TRP 360 376 376 TRP TRP B . n 
B 2 361 THR 361 377 377 THR THR B . n 
B 2 362 GLU 362 378 378 GLU GLU B . n 
B 2 363 THR 363 379 379 THR THR B . n 
B 2 364 THR 364 380 380 THR THR B . n 
B 2 365 GLN 365 381 381 GLN GLN B . n 
B 2 366 LEU 366 382 382 LEU LEU B . n 
B 2 367 GLU 367 383 383 GLU GLU B . n 
B 2 368 VAL 368 384 384 VAL VAL B . n 
B 2 369 ALA 369 385 385 ALA ALA B . n 
B 2 370 VAL 370 386 386 VAL VAL B . n 
B 2 371 SER 371 387 387 SER SER B . n 
B 2 372 GLY 372 388 388 GLY GLY B . n 
B 2 373 ALA 373 389 389 ALA ALA B . n 
B 2 374 ALA 374 390 390 ALA ALA B . n 
B 2 375 GLY 375 391 391 GLY GLY B . n 
B 2 376 ALA 376 392 392 ALA ALA B . n 
B 2 377 ASN 377 393 393 ASN ASN B . n 
B 2 378 LEU 378 394 394 LEU LEU B . n 
B 2 379 ASN 379 395 395 ASN ASN B . n 
B 2 380 GLY 380 396 396 GLY GLY B . n 
B 2 381 ILE 381 397 397 ILE ILE B . n 
B 2 382 ILE 382 398 398 ILE ILE B . n 
B 2 383 TYR 383 399 399 TYR TYR B . n 
B 2 384 LEU 384 400 400 LEU LEU B . n 
B 2 385 LEU 385 401 401 LEU LEU B . n 
B 2 386 GLY 386 402 402 GLY GLY B . n 
B 2 387 GLY 387 403 403 GLY GLY B . n 
B 2 388 GLU 388 404 404 GLU GLU B . n 
B 2 389 GLU 389 405 405 GLU GLU B . n 
B 2 390 ASN 390 406 406 ASN ASN B . n 
B 2 391 ASP 391 407 407 ASP ASP B . n 
B 2 392 LEU 392 408 408 LEU LEU B . n 
B 2 393 ASP 393 409 409 ASP ASP B . n 
B 2 394 PHE 394 410 410 PHE PHE B . n 
B 2 395 PHE 395 411 411 PHE PHE B . n 
B 2 396 THR 396 412 412 THR THR B . n 
B 2 397 LYS 397 413 413 LYS LYS B . n 
B 2 398 PRO 398 414 414 PRO PRO B . n 
B 2 399 SER 399 415 415 SER SER B . n 
B 2 400 ARG 400 416 416 ARG ARG B . n 
B 2 401 LEU 401 417 417 LEU LEU B . n 
B 2 402 ILE 402 418 418 ILE ILE B . n 
B 2 403 GLN 403 419 419 GLN GLN B . n 
B 2 404 CYS 404 420 420 CYS CYS B . n 
B 2 405 PHE 405 421 421 PHE PHE B . n 
B 2 406 ASP 406 422 422 ASP ASP B . n 
B 2 407 THR 407 423 423 THR THR B . n 
B 2 408 GLU 408 424 424 GLU GLU B . n 
B 2 409 THR 409 425 425 THR THR B . n 
B 2 410 ASP 410 426 426 ASP ASP B . n 
B 2 411 LYS 411 427 427 LYS LYS B . n 
B 2 412 CYS 412 428 428 CYS CYS B . n 
B 2 413 HIS 413 429 429 HIS HIS B . n 
B 2 414 VAL 414 430 430 VAL VAL B . n 
B 2 415 LYS 415 431 431 LYS LYS B . n 
B 2 416 PRO 416 432 432 PRO PRO B . n 
B 2 417 TYR 417 433 433 TYR TYR B . n 
B 2 418 VAL 418 434 434 VAL VAL B . n 
B 2 419 LEU 419 435 435 LEU LEU B . n 
B 2 420 PRO 420 436 436 PRO PRO B . n 
B 2 421 PHE 421 437 437 PHE PHE B . n 
B 2 422 ALA 422 438 438 ALA ALA B . n 
B 2 423 GLY 423 439 439 GLY GLY B . n 
B 2 424 ARG 424 440 440 ARG ARG B . n 
B 2 425 MET 425 441 441 MET MET B . n 
B 2 426 HIS 426 442 442 HIS HIS B . n 
B 2 427 ALA 427 443 443 ALA ALA B . n 
B 2 428 ALA 428 444 444 ALA ALA B . n 
B 2 429 VAL 429 445 445 VAL VAL B . n 
B 2 430 HIS 430 446 446 HIS HIS B . n 
B 2 431 LYS 431 447 447 LYS LYS B . n 
B 2 432 ASP 432 448 448 ASP ASP B . n 
B 2 433 LEU 433 449 449 LEU LEU B . n 
B 2 434 VAL 434 450 450 VAL VAL B . n 
B 2 435 PHE 435 451 451 PHE PHE B . n 
B 2 436 ILE 436 452 452 ILE ILE B . n 
B 2 437 VAL 437 453 453 VAL VAL B . n 
B 2 438 ALA 438 454 454 ALA ALA B . n 
B 2 439 GLU 439 455 455 GLU GLU B . n 
B 2 440 GLY 440 456 456 GLY GLY B . n 
B 2 441 ASP 441 457 457 ASP ASP B . n 
B 2 442 SER 442 458 458 SER SER B . n 
B 2 443 LEU 443 459 459 LEU LEU B . n 
B 2 444 VAL 444 460 460 VAL VAL B . n 
B 2 445 CYS 445 461 461 CYS CYS B . n 
B 2 446 TYR 446 462 462 TYR TYR B . n 
B 2 447 ASN 447 463 463 ASN ASN B . n 
B 2 448 PRO 448 464 464 PRO PRO B . n 
B 2 449 LEU 449 465 465 LEU LEU B . n 
B 2 450 LEU 450 466 466 LEU LEU B . n 
B 2 451 ASP 451 467 467 ASP ASP B . n 
B 2 452 SER 452 468 468 SER SER B . n 
B 2 453 PHE 453 469 469 PHE PHE B . n 
B 2 454 THR 454 470 470 THR THR B . n 
B 2 455 ARG 455 471 471 ARG ARG B . n 
B 2 456 LEU 456 472 472 LEU LEU B . n 
B 2 457 CYS 457 473 473 CYS CYS B . n 
B 2 458 LEU 458 474 474 LEU LEU B . n 
B 2 459 PRO 459 475 475 PRO PRO B . n 
B 2 460 GLU 460 476 476 GLU GLU B . n 
B 2 461 ALA 461 477 477 ALA ALA B . n 
B 2 462 TRP 462 478 478 TRP TRP B . n 
B 2 463 SER 463 479 479 SER SER B . n 
B 2 464 SER 464 480 480 SER SER B . n 
B 2 465 ALA 465 481 481 ALA ALA B . n 
B 2 466 PRO 466 482 482 PRO PRO B . n 
B 2 467 SER 467 483 483 SER SER B . n 
B 2 468 LEU 468 484 484 LEU LEU B . n 
B 2 469 TRP 469 485 485 TRP TRP B . n 
B 2 470 LYS 470 486 486 LYS LYS B . n 
B 2 471 ILE 471 487 487 ILE ILE B . n 
B 2 472 ALA 472 488 488 ALA ALA B . n 
B 2 473 SER 473 489 489 SER SER B . n 
B 2 474 CYS 474 490 490 CYS CYS B . n 
B 2 475 ASN 475 491 491 ASN ASN B . n 
B 2 476 GLY 476 492 492 GLY GLY B . n 
B 2 477 SER 477 493 493 SER SER B . n 
B 2 478 ILE 478 494 494 ILE ILE B . n 
B 2 479 TYR 479 495 495 TYR TYR B . n 
B 2 480 VAL 480 496 496 VAL VAL B . n 
B 2 481 PHE 481 497 497 PHE PHE B . n 
B 2 482 ARG 482 498 498 ARG ARG B . n 
B 2 483 ASP 483 499 499 ASP ASP B . n 
B 2 484 ARG 484 500 500 ARG ARG B . n 
B 2 485 TYR 485 501 501 TYR TYR B . n 
B 2 486 LYS 486 502 502 LYS LYS B . n 
B 2 487 LYS 487 503 503 LYS LYS B . n 
B 2 488 GLY 488 504 504 GLY GLY B . n 
B 2 489 ASP 489 505 505 ASP ASP B . n 
B 2 490 ALA 490 506 506 ALA ALA B . n 
B 2 491 ASN 491 507 507 ASN ASN B . n 
B 2 492 THR 492 508 508 THR THR B . n 
B 2 493 TYR 493 509 509 TYR TYR B . n 
B 2 494 LYS 494 510 510 LYS LYS B . n 
B 2 495 LEU 495 511 511 LEU LEU B . n 
B 2 496 ASP 496 512 512 ASP ASP B . n 
B 2 497 PRO 497 513 513 PRO PRO B . n 
B 2 498 ALA 498 514 514 ALA ALA B . n 
B 2 499 THR 499 515 515 THR THR B . n 
B 2 500 SER 500 516 516 SER SER B . n 
B 2 501 ALA 501 517 517 ALA ALA B . n 
B 2 502 VAL 502 518 518 VAL VAL B . n 
B 2 503 THR 503 519 519 THR THR B . n 
B 2 504 VAL 504 520 520 VAL VAL B . n 
B 2 505 THR 505 521 521 THR THR B . n 
B 2 506 ARG 506 522 522 ARG ARG B . n 
B 2 507 GLY 507 523 523 GLY GLY B . n 
B 2 508 ILE 508 524 524 ILE ILE B . n 
B 2 509 LYS 509 525 525 LYS LYS B . n 
B 2 510 VAL 510 526 526 VAL VAL B . n 
B 2 511 LEU 511 527 527 LEU LEU B . n 
B 2 512 LEU 512 528 528 LEU LEU B . n 
B 2 513 THR 513 529 529 THR THR B . n 
B 2 514 ASN 514 530 530 ASN ASN B . n 
B 2 515 LEU 515 531 531 LEU LEU B . n 
B 2 516 GLN 516 532 532 GLN GLN B . n 
B 2 517 PHE 517 533 533 PHE PHE B . n 
B 2 518 VAL 518 534 534 VAL VAL B . n 
B 2 519 LEU 519 535 535 LEU LEU B . n 
B 2 520 ALA 520 536 536 ALA ALA B . n 
C 3 1   MET 1   -19 ?   ?   ?   D . n 
C 3 2   SER 2   -18 ?   ?   ?   D . n 
C 3 3   TRP 3   -17 ?   ?   ?   D . n 
C 3 4   GLU 4   -16 ?   ?   ?   D . n 
C 3 5   GLU 5   -15 ?   ?   ?   D . n 
C 3 6   GLY 6   -14 ?   ?   ?   D . n 
C 3 7   SER 7   -13 ?   ?   ?   D . n 
C 3 8   SER 8   -12 ?   ?   ?   D . n 
C 3 9   GLY 9   -11 ?   ?   ?   D . n 
C 3 10  SER 10  -10 ?   ?   ?   D . n 
C 3 11  SER 11  -9  ?   ?   ?   D . n 
C 3 12  SER 12  -8  ?   ?   ?   D . n 
C 3 13  ASP 13  -7  ?   ?   ?   D . n 
C 3 14  GLU 14  -6  ?   ?   ?   D . n 
C 3 15  GLU 15  -5  ?   ?   ?   D . n 
C 3 16  HIS 16  -4  ?   ?   ?   D . n 
C 3 17  GLY 17  -3  ?   ?   ?   D . n 
C 3 18  GLY 18  -2  ?   ?   ?   D . n 
C 3 19  GLY 19  -1  ?   ?   ?   D . n 
C 3 20  GLY 20  0   ?   ?   ?   D . n 
C 3 21  MET 21  1   1   MET MET D . n 
C 3 22  ARG 22  2   2   ARG ARG D . n 
C 3 23  VAL 23  3   3   VAL VAL D . n 
C 3 24  GLY 24  4   4   GLY GLY D . n 
C 3 25  PRO 25  5   5   PRO PRO D . n 
C 3 26  GLN 26  6   6   GLN GLN D . n 
C 3 27  TYR 27  7   7   TYR TYR D . n 
C 3 28  GLN 28  8   8   GLN GLN D . n 
C 3 29  ALA 29  9   9   ALA ALA D . n 
C 3 30  VAL 30  10  10  VAL VAL D . n 
C 3 31  VAL 31  11  11  VAL VAL D . n 
C 3 32  PRO 32  12  12  PRO PRO D . n 
C 3 33  ASP 33  13  13  ASP ASP D . n 
C 3 34  PHE 34  14  14  PHE PHE D . n 
C 3 35  ASP 35  15  15  ASP ASP D . n 
C 3 36  PRO 36  16  16  PRO PRO D . n 
C 3 37  ALA 37  17  17  ALA ALA D . n 
C 3 38  LYS 38  18  18  LYS LYS D . n 
C 3 39  LEU 39  19  19  LEU LEU D . n 
C 3 40  ALA 40  20  20  ALA ALA D . n 
C 3 41  ARG 41  21  21  ARG ARG D . n 
C 3 42  ARG 42  22  22  ARG ARG D . n 
C 3 43  SER 43  23  23  SER SER D . n 
C 3 44  GLN 44  24  24  GLN GLN D . n 
C 3 45  GLU 45  25  25  GLU GLU D . n 
C 3 46  ARG 46  26  26  ARG ARG D . n 
C 3 47  ASP 47  27  27  ASP ASP D . n 
C 3 48  ASN 48  28  28  ASN ASN D . n 
C 3 49  LEU 49  29  29  LEU LEU D . n 
C 3 50  GLY 50  30  30  GLY GLY D . n 
C 3 51  MET 51  31  31  MET MET D . n 
C 3 52  LEU 52  32  32  LEU LEU D . n 
C 3 53  VAL 53  33  33  VAL VAL D . n 
C 3 54  TRP 54  34  34  TRP TRP D . n 
C 3 55  SER 55  35  35  SER SER D . n 
C 3 56  PRO 56  36  36  PRO PRO D . n 
C 3 57  ASN 57  37  37  ASN ASN D . n 
C 3 58  GLN 58  38  38  GLN GLN D . n 
C 3 59  ASN 59  39  39  ASN ASN D . n 
C 3 60  LEU 60  40  40  LEU LEU D . n 
C 3 61  SER 61  41  41  SER SER D . n 
C 3 62  GLU 62  42  42  GLU GLU D . n 
C 3 63  ALA 63  43  43  ALA ALA D . n 
C 3 64  LYS 64  44  44  LYS LYS D . n 
C 3 65  LEU 65  45  45  LEU LEU D . n 
C 3 66  ASP 66  46  46  ASP ASP D . n 
C 3 67  GLU 67  47  47  GLU GLU D . n 
C 3 68  TYR 68  48  48  TYR TYR D . n 
C 3 69  ILE 69  49  49  ILE ILE D . n 
C 3 70  ALA 70  50  50  ALA ALA D . n 
C 3 71  ILE 71  51  51  ILE ILE D . n 
C 3 72  ALA 72  52  52  ALA ALA D . n 
C 3 73  LYS 73  53  53  LYS LYS D . n 
C 3 74  GLU 74  54  54  GLU GLU D . n 
C 3 75  LYS 75  55  55  LYS LYS D . n 
C 3 76  HIS 76  56  56  HIS HIS D . n 
C 3 77  GLY 77  57  57  GLY GLY D . n 
C 3 78  TYR 78  58  58  TYR TYR D . n 
C 3 79  ASN 79  59  59  ASN ASN D . n 
C 3 80  MET 80  60  60  MET MET D . n 
C 3 81  GLU 81  61  61  GLU GLU D . n 
C 3 82  GLN 82  62  62  GLN GLN D . n 
C 3 83  ALA 83  63  63  ALA ALA D . n 
C 3 84  LEU 84  64  64  LEU LEU D . n 
C 3 85  GLY 85  65  65  GLY GLY D . n 
C 3 86  MET 86  66  66  MET MET D . n 
C 3 87  LEU 87  67  67  LEU LEU D . n 
C 3 88  PHE 88  68  68  PHE PHE D . n 
C 3 89  TRP 89  69  69  TRP TRP D . n 
C 3 90  HIS 90  70  70  HIS HIS D . n 
C 3 91  LYS 91  71  71  LYS LYS D . n 
C 3 92  HIS 92  72  72  HIS HIS D . n 
C 3 93  ASN 93  73  73  ASN ASN D . n 
C 3 94  ILE 94  74  74  ILE ILE D . n 
C 3 95  GLU 95  75  75  GLU GLU D . n 
C 3 96  LYS 96  76  76  LYS LYS D . n 
C 3 97  SER 97  77  77  SER SER D . n 
C 3 98  LEU 98  78  78  LEU LEU D . n 
C 3 99  ALA 99  79  79  ALA ALA D . n 
C 3 100 ASP 100 80  80  ASP ASP D . n 
C 3 101 LEU 101 81  81  LEU LEU D . n 
C 3 102 PRO 102 82  82  PRO PRO D . n 
C 3 103 ASN 103 83  83  ASN ASN D . n 
C 3 104 PHE 104 84  84  PHE PHE D . n 
C 3 105 THR 105 85  85  THR THR D . n 
C 3 106 PRO 106 86  86  PRO PRO D . n 
C 3 107 PHE 107 87  87  PHE PHE D . n 
C 3 108 PRO 108 88  88  PRO PRO D . n 
C 3 109 ASP 109 89  89  ASP ASP D . n 
C 3 110 GLU 110 90  90  GLU GLU D . n 
C 3 111 TRP 111 91  91  TRP TRP D . n 
C 3 112 THR 112 92  92  THR THR D . n 
C 3 113 VAL 113 93  93  VAL VAL D . n 
C 3 114 GLU 114 94  94  GLU GLU D . n 
C 3 115 ASP 115 95  95  ASP ASP D . n 
C 3 116 LYS 116 96  96  LYS LYS D . n 
C 3 117 VAL 117 97  97  VAL VAL D . n 
C 3 118 LEU 118 98  98  LEU LEU D . n 
C 3 119 PHE 119 99  99  PHE PHE D . n 
C 3 120 GLU 120 100 100 GLU GLU D . n 
C 3 121 GLN 121 101 101 GLN GLN D . n 
C 3 122 ALA 122 102 102 ALA ALA D . n 
C 3 123 PHE 123 103 103 PHE PHE D . n 
C 3 124 SER 124 104 104 SER SER D . n 
C 3 125 PHE 125 105 105 PHE PHE D . n 
C 3 126 HIS 126 106 106 HIS HIS D . n 
C 3 127 GLY 127 107 107 GLY GLY D . n 
C 3 128 LYS 128 108 108 LYS LYS D . n 
C 3 129 THR 129 109 109 THR THR D . n 
C 3 130 PHE 130 110 110 PHE PHE D . n 
C 3 131 HIS 131 111 111 HIS HIS D . n 
C 3 132 ARG 132 112 112 ARG ARG D . n 
C 3 133 ILE 133 113 113 ILE ILE D . n 
C 3 134 GLN 134 114 114 GLN GLN D . n 
C 3 135 GLN 135 115 115 GLN GLN D . n 
C 3 136 MET 136 116 116 MET MET D . n 
C 3 137 LEU 137 117 117 LEU LEU D . n 
C 3 138 PRO 138 118 118 PRO PRO D . n 
C 3 139 ASP 139 119 119 ASP ASP D . n 
C 3 140 LYS 140 120 120 LYS LYS D . n 
C 3 141 SER 141 121 121 SER SER D . n 
C 3 142 ILE 142 122 122 ILE ILE D . n 
C 3 143 ALA 143 123 123 ALA ALA D . n 
C 3 144 SER 144 124 124 SER SER D . n 
C 3 145 LEU 145 125 125 LEU LEU D . n 
C 3 146 VAL 146 126 126 VAL VAL D . n 
C 3 147 LYS 147 127 127 LYS LYS D . n 
C 3 148 PHE 148 128 128 PHE PHE D . n 
C 3 149 TYR 149 129 ?   ?   ?   D . n 
C 3 150 TYR 150 130 ?   ?   ?   D . n 
C 3 151 SER 151 131 ?   ?   ?   D . n 
C 3 152 TRP 152 132 ?   ?   ?   D . n 
C 3 153 LYS 153 133 133 LYS LYS D . n 
C 3 154 LYS 154 134 134 LYS LYS D . n 
C 3 155 THR 155 135 135 THR THR D . n 
C 3 156 ARG 156 136 ?   ?   ?   D . n 
C 3 157 THR 157 137 ?   ?   ?   D . n 
C 3 158 LYS 158 138 ?   ?   ?   D . n 
C 3 159 THR 159 139 ?   ?   ?   D . n 
C 3 160 SER 160 140 ?   ?   ?   D . n 
C 3 161 VAL 161 141 ?   ?   ?   D . n 
C 3 162 MET 162 142 ?   ?   ?   D . n 
C 3 163 ASP 163 143 ?   ?   ?   D . n 
C 3 164 ARG 164 144 ?   ?   ?   D . n 
C 3 165 HIS 165 145 ?   ?   ?   D . n 
C 3 166 ALA 166 146 ?   ?   ?   D . n 
C 3 167 ARG 167 147 ?   ?   ?   D . n 
C 3 168 LYS 168 148 ?   ?   ?   D . n 
C 3 169 GLN 169 149 ?   ?   ?   D . n 
C 3 170 LYS 170 150 ?   ?   ?   D . n 
C 3 171 ARG 171 151 ?   ?   ?   D . n 
C 3 172 GLU 172 152 ?   ?   ?   D . n 
C 3 173 ARG 173 153 ?   ?   ?   D . n 
C 3 174 GLU 174 154 ?   ?   ?   D . n 
C 3 175 GLU 175 155 ?   ?   ?   D . n 
C 3 176 SER 176 156 ?   ?   ?   D . n 
C 3 177 GLU 177 157 ?   ?   ?   D . n 
C 3 178 ASP 178 158 ?   ?   ?   D . n 
C 3 179 GLU 179 159 ?   ?   ?   D . n 
C 3 180 LEU 180 160 ?   ?   ?   D . n 
C 3 181 GLU 181 161 ?   ?   ?   D . n 
C 3 182 GLU 182 162 ?   ?   ?   D . n 
C 3 183 ALA 183 163 ?   ?   ?   D . n 
C 3 184 ASN 184 164 ?   ?   ?   D . n 
C 3 185 GLY 185 165 ?   ?   ?   D . n 
C 3 186 ASN 186 166 ?   ?   ?   D . n 
C 3 187 ASN 187 167 ?   ?   ?   D . n 
C 3 188 PRO 188 168 ?   ?   ?   D . n 
C 3 189 ILE 189 169 ?   ?   ?   D . n 
C 3 190 ASP 190 170 ?   ?   ?   D . n 
C 3 191 ILE 191 171 ?   ?   ?   D . n 
C 3 192 GLU 192 172 ?   ?   ?   D . n 
C 3 193 VAL 193 173 ?   ?   ?   D . n 
C 3 194 ASP 194 174 ?   ?   ?   D . n 
C 3 195 GLN 195 175 ?   ?   ?   D . n 
C 3 196 ASN 196 176 ?   ?   ?   D . n 
C 3 197 LYS 197 177 ?   ?   ?   D . n 
C 3 198 GLU 198 178 ?   ?   ?   D . n 
C 3 199 SER 199 179 ?   ?   ?   D . n 
C 3 200 LYS 200 180 ?   ?   ?   D . n 
C 3 201 LYS 201 181 ?   ?   ?   D . n 
C 3 202 GLU 202 182 ?   ?   ?   D . n 
C 3 203 VAL 203 183 ?   ?   ?   D . n 
C 3 204 PRO 204 184 ?   ?   ?   D . n 
C 3 205 PRO 205 185 ?   ?   ?   D . n 
C 3 206 THR 206 186 ?   ?   ?   D . n 
C 3 207 GLU 207 187 ?   ?   ?   D . n 
C 3 208 THR 208 188 ?   ?   ?   D . n 
C 3 209 VAL 209 189 ?   ?   ?   D . n 
C 3 210 PRO 210 190 ?   ?   ?   D . n 
C 3 211 GLN 211 191 ?   ?   ?   D . n 
C 3 212 VAL 212 192 ?   ?   ?   D . n 
C 3 213 LYS 213 193 ?   ?   ?   D . n 
C 3 214 LYS 214 194 ?   ?   ?   D . n 
C 3 215 GLU 215 195 ?   ?   ?   D . n 
C 3 216 LYS 216 196 ?   ?   ?   D . n 
C 3 217 HIS 217 197 ?   ?   ?   D . n 
C 3 218 SER 218 198 ?   ?   ?   D . n 
C 3 219 THR 219 199 ?   ?   ?   D . n 
C 3 220 GLN 220 200 ?   ?   ?   D . n 
C 3 221 ALA 221 201 ?   ?   ?   D . n 
C 3 222 LYS 222 202 ?   ?   ?   D . n 
C 3 223 ASN 223 203 ?   ?   ?   D . n 
C 3 224 ARG 224 204 ?   ?   ?   D . n 
C 3 225 ALA 225 205 ?   ?   ?   D . n 
C 3 226 LYS 226 206 ?   ?   ?   D . n 
C 3 227 ARG 227 207 ?   ?   ?   D . n 
C 3 228 LYS 228 208 ?   ?   ?   D . n 
C 3 229 PRO 229 209 ?   ?   ?   D . n 
C 3 230 PRO 230 210 ?   ?   ?   D . n 
C 3 231 LYS 231 211 ?   ?   ?   D . n 
C 3 232 GLY 232 212 ?   ?   ?   D . n 
C 3 233 MET 233 213 ?   ?   ?   D . n 
C 3 234 PHE 234 214 ?   ?   ?   D . n 
C 3 235 LEU 235 215 ?   ?   ?   D . n 
C 3 236 SER 236 216 ?   ?   ?   D . n 
C 3 237 GLN 237 217 ?   ?   ?   D . n 
C 3 238 GLU 238 218 ?   ?   ?   D . n 
C 3 239 ASP 239 219 ?   ?   ?   D . n 
C 3 240 VAL 240 220 ?   ?   ?   D . n 
C 3 241 GLU 241 221 ?   ?   ?   D . n 
C 3 242 ALA 242 222 ?   ?   ?   D . n 
C 3 243 VAL 243 223 ?   ?   ?   D . n 
C 3 244 SER 244 224 ?   ?   ?   D . n 
C 3 245 ALA 245 225 ?   ?   ?   D . n 
C 3 246 ASN 246 226 ?   ?   ?   D . n 
C 3 247 ALA 247 227 ?   ?   ?   D . n 
C 3 248 THR 248 228 ?   ?   ?   D . n 
C 3 249 ALA 249 229 ?   ?   ?   D . n 
C 3 250 ALA 250 230 ?   ?   ?   D . n 
C 3 251 THR 251 231 ?   ?   ?   D . n 
C 3 252 THR 252 232 ?   ?   ?   D . n 
C 3 253 VAL 253 233 ?   ?   ?   D . n 
C 3 254 LEU 254 234 ?   ?   ?   D . n 
C 3 255 ARG 255 235 ?   ?   ?   D . n 
C 3 256 GLN 256 236 ?   ?   ?   D . n 
C 3 257 LEU 257 237 ?   ?   ?   D . n 
C 3 258 ASP 258 238 ?   ?   ?   D . n 
C 3 259 MET 259 239 ?   ?   ?   D . n 
C 3 260 GLU 260 240 ?   ?   ?   D . n 
C 3 261 LEU 261 241 ?   ?   ?   D . n 
C 3 262 VAL 262 242 ?   ?   ?   D . n 
C 3 263 SER 263 243 ?   ?   ?   D . n 
C 3 264 VAL 264 244 ?   ?   ?   D . n 
C 3 265 LYS 265 245 ?   ?   ?   D . n 
C 3 266 ARG 266 246 ?   ?   ?   D . n 
C 3 267 GLN 267 247 ?   ?   ?   D . n 
C 3 268 ILE 268 248 ?   ?   ?   D . n 
C 3 269 GLN 269 249 ?   ?   ?   D . n 
C 3 270 ASN 270 250 ?   ?   ?   D . n 
C 3 271 ILE 271 251 ?   ?   ?   D . n 
C 3 272 LYS 272 252 ?   ?   ?   D . n 
C 3 273 GLN 273 253 ?   ?   ?   D . n 
C 3 274 THR 274 254 ?   ?   ?   D . n 
C 3 275 ASN 275 255 ?   ?   ?   D . n 
C 3 276 SER 276 256 ?   ?   ?   D . n 
C 3 277 ALA 277 257 ?   ?   ?   D . n 
C 3 278 LEU 278 258 ?   ?   ?   D . n 
C 3 279 LYS 279 259 ?   ?   ?   D . n 
C 3 280 GLU 280 260 ?   ?   ?   D . n 
C 3 281 LYS 281 261 ?   ?   ?   D . n 
C 3 282 LEU 282 262 ?   ?   ?   D . n 
C 3 283 ASP 283 263 ?   ?   ?   D . n 
C 3 284 GLY 284 264 ?   ?   ?   D . n 
C 3 285 GLY 285 265 ?   ?   ?   D . n 
C 3 286 ILE 286 266 ?   ?   ?   D . n 
C 3 287 GLU 287 267 ?   ?   ?   D . n 
C 3 288 PRO 288 268 ?   ?   ?   D . n 
C 3 289 TYR 289 269 ?   ?   ?   D . n 
C 3 290 ARG 290 270 ?   ?   ?   D . n 
C 3 291 LEU 291 271 ?   ?   ?   D . n 
C 3 292 PRO 292 272 ?   ?   ?   D . n 
C 3 293 GLU 293 273 ?   ?   ?   D . n 
C 3 294 VAL 294 274 ?   ?   ?   D . n 
C 3 295 ILE 295 275 ?   ?   ?   D . n 
C 3 296 GLN 296 276 ?   ?   ?   D . n 
C 3 297 LYS 297 277 ?   ?   ?   D . n 
C 3 298 CYS 298 278 ?   ?   ?   D . n 
C 3 299 ASN 299 279 ?   ?   ?   D . n 
C 3 300 ALA 300 280 ?   ?   ?   D . n 
C 3 301 ARG 301 281 ?   ?   ?   D . n 
C 3 302 TRP 302 282 ?   ?   ?   D . n 
C 3 303 THR 303 283 ?   ?   ?   D . n 
C 3 304 THR 304 284 ?   ?   ?   D . n 
C 3 305 GLU 305 285 ?   ?   ?   D . n 
C 3 306 GLU 306 286 ?   ?   ?   D . n 
C 3 307 GLN 307 287 ?   ?   ?   D . n 
C 3 308 LEU 308 288 ?   ?   ?   D . n 
C 3 309 LEU 309 289 ?   ?   ?   D . n 
C 3 310 ALA 310 290 ?   ?   ?   D . n 
C 3 311 VAL 311 291 ?   ?   ?   D . n 
C 3 312 GLN 312 292 ?   ?   ?   D . n 
C 3 313 ALA 313 293 ?   ?   ?   D . n 
C 3 314 ILE 314 294 ?   ?   ?   D . n 
C 3 315 ARG 315 295 ?   ?   ?   D . n 
C 3 316 LYS 316 296 ?   ?   ?   D . n 
C 3 317 TYR 317 297 ?   ?   ?   D . n 
C 3 318 GLY 318 298 ?   ?   ?   D . n 
C 3 319 ARG 319 299 ?   ?   ?   D . n 
C 3 320 ASP 320 300 ?   ?   ?   D . n 
C 3 321 PHE 321 301 ?   ?   ?   D . n 
C 3 322 GLN 322 302 ?   ?   ?   D . n 
C 3 323 ALA 323 303 ?   ?   ?   D . n 
C 3 324 ILE 324 304 ?   ?   ?   D . n 
C 3 325 SER 325 305 ?   ?   ?   D . n 
C 3 326 ASP 326 306 ?   ?   ?   D . n 
C 3 327 VAL 327 307 ?   ?   ?   D . n 
C 3 328 ILE 328 308 ?   ?   ?   D . n 
C 3 329 GLY 329 309 ?   ?   ?   D . n 
C 3 330 ASN 330 310 ?   ?   ?   D . n 
C 3 331 LYS 331 311 ?   ?   ?   D . n 
C 3 332 SER 332 312 ?   ?   ?   D . n 
C 3 333 VAL 333 313 ?   ?   ?   D . n 
C 3 334 VAL 334 314 ?   ?   ?   D . n 
C 3 335 GLN 335 315 ?   ?   ?   D . n 
C 3 336 VAL 336 316 ?   ?   ?   D . n 
C 3 337 LYS 337 317 ?   ?   ?   D . n 
C 3 338 ASN 338 318 ?   ?   ?   D . n 
C 3 339 PHE 339 319 ?   ?   ?   D . n 
C 3 340 PHE 340 320 ?   ?   ?   D . n 
C 3 341 VAL 341 321 ?   ?   ?   D . n 
C 3 342 ASN 342 322 ?   ?   ?   D . n 
C 3 343 TYR 343 323 ?   ?   ?   D . n 
C 3 344 ARG 344 324 ?   ?   ?   D . n 
C 3 345 ARG 345 325 ?   ?   ?   D . n 
C 3 346 ARG 346 326 ?   ?   ?   D . n 
C 3 347 PHE 347 327 ?   ?   ?   D . n 
C 3 348 ASN 348 328 ?   ?   ?   D . n 
C 3 349 ILE 349 329 ?   ?   ?   D . n 
C 3 350 ASP 350 330 ?   ?   ?   D . n 
C 3 351 GLU 351 331 ?   ?   ?   D . n 
C 3 352 VAL 352 332 ?   ?   ?   D . n 
C 3 353 LEU 353 333 ?   ?   ?   D . n 
C 3 354 GLN 354 334 ?   ?   ?   D . n 
C 3 355 GLU 355 335 ?   ?   ?   D . n 
C 3 356 TRP 356 336 ?   ?   ?   D . n 
C 3 357 GLU 357 337 ?   ?   ?   D . n 
C 3 358 ALA 358 338 ?   ?   ?   D . n 
C 3 359 GLU 359 339 ?   ?   ?   D . n 
C 3 360 HIS 360 340 ?   ?   ?   D . n 
C 3 361 GLY 361 341 ?   ?   ?   D . n 
C 3 362 LYS 362 342 ?   ?   ?   D . n 
C 3 363 GLU 363 343 ?   ?   ?   D . n 
C 3 364 GLU 364 344 ?   ?   ?   D . n 
C 3 365 THR 365 345 ?   ?   ?   D . n 
C 3 366 ASN 366 346 ?   ?   ?   D . n 
C 3 367 GLY 367 347 ?   ?   ?   D . n 
C 3 368 PRO 368 348 ?   ?   ?   D . n 
C 3 369 SER 369 349 ?   ?   ?   D . n 
C 3 370 ASN 370 350 ?   ?   ?   D . n 
C 3 371 GLN 371 351 ?   ?   ?   D . n 
C 3 372 LYS 372 352 ?   ?   ?   D . n 
C 3 373 PRO 373 353 ?   ?   ?   D . n 
C 3 374 VAL 374 354 ?   ?   ?   D . n 
C 3 375 LYS 375 355 ?   ?   ?   D . n 
C 3 376 SER 376 356 ?   ?   ?   D . n 
C 3 377 PRO 377 357 ?   ?   ?   D . n 
C 3 378 ASP 378 358 ?   ?   ?   D . n 
C 3 379 ASN 379 359 ?   ?   ?   D . n 
C 3 380 SER 380 360 ?   ?   ?   D . n 
C 3 381 ILE 381 361 ?   ?   ?   D . n 
C 3 382 LYS 382 362 ?   ?   ?   D . n 
C 3 383 MET 383 363 ?   ?   ?   D . n 
C 3 384 PRO 384 364 ?   ?   ?   D . n 
C 3 385 GLU 385 365 ?   ?   ?   D . n 
C 3 386 GLU 386 366 ?   ?   ?   D . n 
C 3 387 GLU 387 367 ?   ?   ?   D . n 
C 3 388 ASP 388 368 ?   ?   ?   D . n 
C 3 389 GLU 389 369 ?   ?   ?   D . n 
C 3 390 ALA 390 370 ?   ?   ?   D . n 
C 3 391 PRO 391 371 ?   ?   ?   D . n 
C 3 392 VAL 392 372 ?   ?   ?   D . n 
C 3 393 LEU 393 373 ?   ?   ?   D . n 
C 3 394 ASP 394 374 ?   ?   ?   D . n 
C 3 395 VAL 395 375 ?   ?   ?   D . n 
C 3 396 ARG 396 376 ?   ?   ?   D . n 
C 3 397 TYR 397 377 ?   ?   ?   D . n 
C 3 398 ALA 398 378 ?   ?   ?   D . n 
C 3 399 SER 399 379 ?   ?   ?   D . n 
C 3 400 ALA 400 380 ?   ?   ?   D . n 
C 3 401 SER 401 381 ?   ?   ?   D . n 
D 2 1   MET 1   17  ?   ?   ?   E . n 
D 2 2   GLU 2   18  ?   ?   ?   E . n 
D 2 3   SER 3   19  ?   ?   ?   E . n 
D 2 4   PRO 4   20  ?   ?   ?   E . n 
D 2 5   GLU 5   21  ?   ?   ?   E . n 
D 2 6   GLU 6   22  ?   ?   ?   E . n 
D 2 7   PRO 7   23  23  PRO PRO E . n 
D 2 8   GLY 8   24  24  GLY GLY E . n 
D 2 9   ALA 9   25  25  ALA ALA E . n 
D 2 10  SER 10  26  26  SER SER E . n 
D 2 11  MET 11  27  27  MET MET E . n 
D 2 12  ASP 12  28  28  ASP ASP E . n 
D 2 13  GLU 13  29  29  GLU GLU E . n 
D 2 14  ASN 14  30  30  ASN ASN E . n 
D 2 15  TYR 15  31  31  TYR TYR E . n 
D 2 16  PHE 16  32  32  PHE PHE E . n 
D 2 17  VAL 17  33  33  VAL VAL E . n 
D 2 18  ASN 18  34  34  ASN ASN E . n 
D 2 19  TYR 19  35  35  TYR TYR E . n 
D 2 20  THR 20  36  36  THR THR E . n 
D 2 21  PHE 21  37  37  PHE PHE E . n 
D 2 22  LYS 22  38  38  LYS LYS E . n 
D 2 23  ASP 23  39  39  ASP ASP E . n 
D 2 24  ARG 24  40  40  ARG ARG E . n 
D 2 25  SER 25  41  41  SER SER E . n 
D 2 26  HIS 26  42  42  HIS HIS E . n 
D 2 27  SER 27  43  43  SER SER E . n 
D 2 28  GLY 28  44  44  GLY GLY E . n 
D 2 29  ARG 29  45  45  ARG ARG E . n 
D 2 30  VAL 30  46  46  VAL VAL E . n 
D 2 31  ALA 31  47  47  ALA ALA E . n 
D 2 32  GLN 32  48  48  GLN GLN E . n 
D 2 33  GLY 33  49  49  GLY GLY E . n 
D 2 34  ILE 34  50  50  ILE ILE E . n 
D 2 35  MET 35  51  51  MET MET E . n 
D 2 36  LYS 36  52  52  LYS LYS E . n 
D 2 37  LEU 37  53  53  LEU LEU E . n 
D 2 38  CYS 38  54  54  CYS CYS E . n 
D 2 39  LEU 39  55  55  LEU LEU E . n 
D 2 40  GLU 40  56  56  GLU GLU E . n 
D 2 41  GLU 41  57  57  GLU GLU E . n 
D 2 42  GLU 42  58  58  GLU GLU E . n 
D 2 43  LEU 43  59  59  LEU LEU E . n 
D 2 44  PHE 44  60  60  PHE PHE E . n 
D 2 45  ALA 45  61  61  ALA ALA E . n 
D 2 46  ASP 46  62  62  ASP ASP E . n 
D 2 47  VAL 47  63  63  VAL VAL E . n 
D 2 48  THR 48  64  64  THR THR E . n 
D 2 49  ILE 49  65  65  ILE ILE E . n 
D 2 50  SER 50  66  66  SER SER E . n 
D 2 51  VAL 51  67  67  VAL VAL E . n 
D 2 52  GLU 52  68  68  GLU GLU E . n 
D 2 53  GLY 53  69  69  GLY GLY E . n 
D 2 54  ARG 54  70  70  ARG ARG E . n 
D 2 55  GLU 55  71  71  GLU GLU E . n 
D 2 56  PHE 56  72  72  PHE PHE E . n 
D 2 57  GLN 57  73  73  GLN GLN E . n 
D 2 58  LEU 58  74  74  LEU LEU E . n 
D 2 59  HIS 59  75  75  HIS HIS E . n 
D 2 60  ARG 60  76  76  ARG ARG E . n 
D 2 61  LEU 61  77  77  LEU LEU E . n 
D 2 62  VAL 62  78  78  VAL VAL E . n 
D 2 63  LEU 63  79  79  LEU LEU E . n 
D 2 64  SER 64  80  80  SER SER E . n 
D 2 65  ALA 65  81  81  ALA ALA E . n 
D 2 66  GLN 66  82  82  GLN GLN E . n 
D 2 67  SER 67  83  83  SER SER E . n 
D 2 68  CYS 68  84  84  CYS CYS E . n 
D 2 69  PHE 69  85  85  PHE PHE E . n 
D 2 70  PHE 70  86  86  PHE PHE E . n 
D 2 71  ARG 71  87  87  ARG ARG E . n 
D 2 72  SER 72  88  88  SER SER E . n 
D 2 73  MET 73  89  89  MET MET E . n 
D 2 74  PHE 74  90  90  PHE PHE E . n 
D 2 75  THR 75  91  91  THR THR E . n 
D 2 76  SER 76  92  92  SER SER E . n 
D 2 77  ASN 77  93  93  ASN ASN E . n 
D 2 78  LEU 78  94  94  LEU LEU E . n 
D 2 79  LYS 79  95  95  LYS LYS E . n 
D 2 80  GLU 80  96  96  GLU GLU E . n 
D 2 81  ALA 81  97  97  ALA ALA E . n 
D 2 82  HIS 82  98  98  HIS HIS E . n 
D 2 83  ASN 83  99  99  ASN ASN E . n 
D 2 84  ARG 84  100 100 ARG ARG E . n 
D 2 85  VAL 85  101 101 VAL VAL E . n 
D 2 86  ILE 86  102 102 ILE ILE E . n 
D 2 87  VAL 87  103 103 VAL VAL E . n 
D 2 88  LEU 88  104 104 LEU LEU E . n 
D 2 89  GLN 89  105 105 GLN GLN E . n 
D 2 90  ASP 90  106 106 ASP ASP E . n 
D 2 91  VAL 91  107 107 VAL VAL E . n 
D 2 92  SER 92  108 108 SER SER E . n 
D 2 93  GLU 93  109 109 GLU GLU E . n 
D 2 94  SER 94  110 110 SER SER E . n 
D 2 95  VAL 95  111 111 VAL VAL E . n 
D 2 96  PHE 96  112 112 PHE PHE E . n 
D 2 97  GLN 97  113 113 GLN GLN E . n 
D 2 98  LEU 98  114 114 LEU LEU E . n 
D 2 99  LEU 99  115 115 LEU LEU E . n 
D 2 100 VAL 100 116 116 VAL VAL E . n 
D 2 101 ASP 101 117 117 ASP ASP E . n 
D 2 102 TYR 102 118 118 TYR TYR E . n 
D 2 103 ILE 103 119 119 ILE ILE E . n 
D 2 104 TYR 104 120 120 TYR TYR E . n 
D 2 105 HIS 105 121 121 HIS HIS E . n 
D 2 106 GLY 106 122 122 GLY GLY E . n 
D 2 107 THR 107 123 123 THR THR E . n 
D 2 108 VAL 108 124 124 VAL VAL E . n 
D 2 109 LYS 109 125 125 LYS LYS E . n 
D 2 110 LEU 110 126 126 LEU LEU E . n 
D 2 111 ARG 111 127 127 ARG ARG E . n 
D 2 112 ALA 112 128 128 ALA ALA E . n 
D 2 113 GLU 113 129 129 GLU GLU E . n 
D 2 114 GLU 114 130 130 GLU GLU E . n 
D 2 115 LEU 115 131 131 LEU LEU E . n 
D 2 116 GLN 116 132 132 GLN GLN E . n 
D 2 117 GLU 117 133 133 GLU GLU E . n 
D 2 118 ILE 118 134 134 ILE ILE E . n 
D 2 119 TYR 119 135 135 TYR TYR E . n 
D 2 120 GLU 120 136 136 GLU GLU E . n 
D 2 121 VAL 121 137 137 VAL VAL E . n 
D 2 122 SER 122 138 138 SER SER E . n 
D 2 123 ASP 123 139 139 ASP ASP E . n 
D 2 124 MET 124 140 140 MET MET E . n 
D 2 125 TYR 125 141 141 TYR TYR E . n 
D 2 126 GLN 126 142 142 GLN GLN E . n 
D 2 127 LEU 127 143 143 LEU LEU E . n 
D 2 128 THR 128 144 144 THR THR E . n 
D 2 129 SER 129 145 145 SER SER E . n 
D 2 130 LEU 130 146 146 LEU LEU E . n 
D 2 131 PHE 131 147 147 PHE PHE E . n 
D 2 132 GLU 132 148 148 GLU GLU E . n 
D 2 133 GLU 133 149 149 GLU GLU E . n 
D 2 134 CYS 134 150 150 CYS CYS E . n 
D 2 135 SER 135 151 151 SER SER E . n 
D 2 136 ARG 136 152 152 ARG ARG E . n 
D 2 137 PHE 137 153 153 PHE PHE E . n 
D 2 138 LEU 138 154 154 LEU LEU E . n 
D 2 139 ALA 139 155 155 ALA ALA E . n 
D 2 140 ARG 140 156 156 ARG ARG E . n 
D 2 141 THR 141 157 157 THR THR E . n 
D 2 142 VAL 142 158 158 VAL VAL E . n 
D 2 143 GLN 143 159 159 GLN GLN E . n 
D 2 144 VAL 144 160 160 VAL VAL E . n 
D 2 145 GLY 145 161 161 GLY GLY E . n 
D 2 146 ASN 146 162 162 ASN ASN E . n 
D 2 147 CYS 147 163 163 CYS CYS E . n 
D 2 148 LEU 148 164 164 LEU LEU E . n 
D 2 149 GLN 149 165 165 GLN GLN E . n 
D 2 150 VAL 150 166 166 VAL VAL E . n 
D 2 151 MET 151 167 167 MET MET E . n 
D 2 152 TRP 152 168 168 TRP TRP E . n 
D 2 153 LEU 153 169 169 LEU LEU E . n 
D 2 154 ALA 154 170 170 ALA ALA E . n 
D 2 155 ASP 155 171 171 ASP ASP E . n 
D 2 156 ARG 156 172 172 ARG ARG E . n 
D 2 157 HIS 157 173 173 HIS HIS E . n 
D 2 158 SER 158 174 174 SER SER E . n 
D 2 159 ASP 159 175 175 ASP ASP E . n 
D 2 160 PRO 160 176 176 PRO PRO E . n 
D 2 161 GLU 161 177 177 GLU GLU E . n 
D 2 162 LEU 162 178 178 LEU LEU E . n 
D 2 163 TYR 163 179 179 TYR TYR E . n 
D 2 164 THR 164 180 180 THR THR E . n 
D 2 165 ALA 165 181 181 ALA ALA E . n 
D 2 166 ALA 166 182 182 ALA ALA E . n 
D 2 167 LYS 167 183 183 LYS LYS E . n 
D 2 168 HIS 168 184 184 HIS HIS E . n 
D 2 169 CYS 169 185 185 CYS CYS E . n 
D 2 170 ALA 170 186 186 ALA ALA E . n 
D 2 171 LYS 171 187 187 LYS LYS E . n 
D 2 172 THR 172 188 188 THR THR E . n 
D 2 173 HIS 173 189 189 HIS HIS E . n 
D 2 174 LEU 174 190 190 LEU LEU E . n 
D 2 175 ALA 175 191 191 ALA ALA E . n 
D 2 176 GLN 176 192 192 GLN GLN E . n 
D 2 177 LEU 177 193 193 LEU LEU E . n 
D 2 178 GLN 178 194 194 GLN GLN E . n 
D 2 179 ASN 179 195 195 ASN ASN E . n 
D 2 180 THR 180 196 196 THR THR E . n 
D 2 181 GLU 181 197 197 GLU GLU E . n 
D 2 182 GLU 182 198 198 GLU GLU E . n 
D 2 183 PHE 183 199 199 PHE PHE E . n 
D 2 184 LEU 184 200 200 LEU LEU E . n 
D 2 185 HIS 185 201 201 HIS HIS E . n 
D 2 186 LEU 186 202 202 LEU LEU E . n 
D 2 187 PRO 187 203 203 PRO PRO E . n 
D 2 188 HIS 188 204 204 HIS HIS E . n 
D 2 189 ARG 189 205 205 ARG ARG E . n 
D 2 190 LEU 190 206 206 LEU LEU E . n 
D 2 191 LEU 191 207 207 LEU LEU E . n 
D 2 192 THR 192 208 208 THR THR E . n 
D 2 193 ASP 193 209 209 ASP ASP E . n 
D 2 194 ILE 194 210 210 ILE ILE E . n 
D 2 195 ILE 195 211 211 ILE ILE E . n 
D 2 196 SER 196 212 212 SER SER E . n 
D 2 197 ASP 197 213 213 ASP ASP E . n 
D 2 198 GLY 198 214 214 GLY GLY E . n 
D 2 199 VAL 199 215 215 VAL VAL E . n 
D 2 200 PRO 200 216 216 PRO PRO E . n 
D 2 201 CYS 201 217 217 CYS CYS E . n 
D 2 202 SER 202 218 218 SER SER E . n 
D 2 203 GLN 203 219 219 GLN GLN E . n 
D 2 204 ASN 204 220 220 ASN ASN E . n 
D 2 205 PRO 205 221 221 PRO PRO E . n 
D 2 206 THR 206 222 222 THR THR E . n 
D 2 207 GLU 207 223 223 GLU GLU E . n 
D 2 208 ALA 208 224 224 ALA ALA E . n 
D 2 209 ILE 209 225 225 ILE ILE E . n 
D 2 210 GLU 210 226 226 GLU GLU E . n 
D 2 211 ALA 211 227 227 ALA ALA E . n 
D 2 212 TRP 212 228 228 TRP TRP E . n 
D 2 213 ILE 213 229 229 ILE ILE E . n 
D 2 214 ASN 214 230 230 ASN ASN E . n 
D 2 215 PHE 215 231 231 PHE PHE E . n 
D 2 216 ASN 216 232 232 ASN ASN E . n 
D 2 217 LYS 217 233 233 LYS LYS E . n 
D 2 218 GLU 218 234 234 GLU GLU E . n 
D 2 219 GLU 219 235 235 GLU GLU E . n 
D 2 220 ARG 220 236 236 ARG ARG E . n 
D 2 221 GLU 221 237 237 GLU GLU E . n 
D 2 222 ALA 222 238 238 ALA ALA E . n 
D 2 223 PHE 223 239 239 PHE PHE E . n 
D 2 224 ALA 224 240 240 ALA ALA E . n 
D 2 225 GLU 225 241 241 GLU GLU E . n 
D 2 226 SER 226 242 242 SER SER E . n 
D 2 227 LEU 227 243 243 LEU LEU E . n 
D 2 228 ARG 228 244 244 ARG ARG E . n 
D 2 229 THR 229 245 245 THR THR E . n 
D 2 230 SER 230 246 246 SER SER E . n 
D 2 231 LEU 231 247 247 LEU LEU E . n 
D 2 232 LYS 232 248 248 LYS LYS E . n 
D 2 233 GLU 233 249 249 GLU GLU E . n 
D 2 234 ILE 234 250 250 ILE ILE E . n 
D 2 235 GLY 235 251 251 GLY GLY E . n 
D 2 236 GLU 236 252 252 GLU GLU E . n 
D 2 237 ASN 237 253 253 ASN ASN E . n 
D 2 238 VAL 238 254 254 VAL VAL E . n 
D 2 239 HIS 239 255 255 HIS HIS E . n 
D 2 240 ILE 240 256 256 ILE ILE E . n 
D 2 241 TYR 241 257 257 TYR TYR E . n 
D 2 242 LEU 242 258 258 LEU LEU E . n 
D 2 243 ILE 243 259 259 ILE ILE E . n 
D 2 244 GLY 244 260 260 GLY GLY E . n 
D 2 245 LYS 245 261 261 LYS LYS E . n 
D 2 246 GLU 246 262 262 GLU GLU E . n 
D 2 247 SER 247 263 263 SER SER E . n 
D 2 248 SER 248 264 264 SER SER E . n 
D 2 249 ARG 249 265 265 ARG ARG E . n 
D 2 250 THR 250 266 266 THR THR E . n 
D 2 251 HIS 251 267 267 HIS HIS E . n 
D 2 252 SER 252 268 268 SER SER E . n 
D 2 253 LEU 253 269 269 LEU LEU E . n 
D 2 254 ALA 254 270 270 ALA ALA E . n 
D 2 255 VAL 255 271 271 VAL VAL E . n 
D 2 256 SER 256 272 272 SER SER E . n 
D 2 257 LEU 257 273 273 LEU LEU E . n 
D 2 258 HIS 258 274 274 HIS HIS E . n 
D 2 259 CYS 259 275 275 CYS CYS E . n 
D 2 260 ALA 260 276 276 ALA ALA E . n 
D 2 261 GLU 261 277 277 GLU GLU E . n 
D 2 262 ASP 262 278 278 ASP ASP E . n 
D 2 263 ASP 263 279 279 ASP ASP E . n 
D 2 264 SER 264 280 280 SER SER E . n 
D 2 265 ILE 265 281 281 ILE ILE E . n 
D 2 266 SER 266 282 282 SER SER E . n 
D 2 267 VAL 267 283 283 VAL VAL E . n 
D 2 268 SER 268 284 284 SER SER E . n 
D 2 269 GLY 269 285 285 GLY GLY E . n 
D 2 270 GLN 270 286 286 GLN GLN E . n 
D 2 271 ASN 271 287 287 ASN ASN E . n 
D 2 272 SER 272 288 288 SER SER E . n 
D 2 273 LEU 273 289 289 LEU LEU E . n 
D 2 274 CYS 274 290 290 CYS CYS E . n 
D 2 275 HIS 275 291 291 HIS HIS E . n 
D 2 276 GLN 276 292 292 GLN GLN E . n 
D 2 277 ILE 277 293 293 ILE ILE E . n 
D 2 278 THR 278 294 294 THR THR E . n 
D 2 279 ALA 279 295 295 ALA ALA E . n 
D 2 280 ALA 280 296 296 ALA ALA E . n 
D 2 281 CYS 281 297 297 CYS CYS E . n 
D 2 282 LYS 282 298 298 LYS LYS E . n 
D 2 283 HIS 283 299 299 HIS HIS E . n 
D 2 284 GLY 284 300 300 GLY GLY E . n 
D 2 285 GLY 285 301 301 GLY GLY E . n 
D 2 286 ASP 286 302 302 ASP ASP E . n 
D 2 287 LEU 287 303 303 LEU LEU E . n 
D 2 288 TYR 288 304 304 TYR TYR E . n 
D 2 289 VAL 289 305 305 VAL VAL E . n 
D 2 290 VAL 290 306 306 VAL VAL E . n 
D 2 291 GLY 291 307 307 GLY GLY E . n 
D 2 292 GLY 292 308 308 GLY GLY E . n 
D 2 293 SER 293 309 309 SER SER E . n 
D 2 294 ILE 294 310 310 ILE ILE E . n 
D 2 295 PRO 295 311 311 PRO PRO E . n 
D 2 296 ARG 296 312 312 ARG ARG E . n 
D 2 297 PRO 297 313 313 PRO PRO E . n 
D 2 298 ARG 298 314 314 ARG ARG E . n 
D 2 299 ARG 299 315 315 ARG ARG E . n 
D 2 300 MET 300 316 316 MET MET E . n 
D 2 301 TRP 301 317 317 TRP TRP E . n 
D 2 302 LYS 302 318 318 LYS LYS E . n 
D 2 303 CYS 303 319 319 CYS CYS E . n 
D 2 304 ASN 304 320 320 ASN ASN E . n 
D 2 305 ASN 305 321 321 ASN ASN E . n 
D 2 306 ALA 306 322 322 ALA ALA E . n 
D 2 307 THR 307 323 323 THR THR E . n 
D 2 308 VAL 308 324 324 VAL VAL E . n 
D 2 309 ASP 309 325 325 ASP ASP E . n 
D 2 310 TRP 310 326 326 TRP TRP E . n 
D 2 311 GLU 311 327 327 GLU GLU E . n 
D 2 312 TRP 312 328 328 TRP TRP E . n 
D 2 313 CYS 313 329 329 CYS CYS E . n 
D 2 314 ALA 314 330 330 ALA ALA E . n 
D 2 315 PRO 315 331 331 PRO PRO E . n 
D 2 316 LEU 316 332 332 LEU LEU E . n 
D 2 317 PRO 317 333 333 PRO PRO E . n 
D 2 318 ARG 318 334 334 ARG ARG E . n 
D 2 319 ASP 319 335 335 ASP ASP E . n 
D 2 320 ARG 320 336 336 ARG ARG E . n 
D 2 321 LEU 321 337 337 LEU LEU E . n 
D 2 322 GLN 322 338 338 GLN GLN E . n 
D 2 323 HIS 323 339 339 HIS HIS E . n 
D 2 324 THR 324 340 340 THR THR E . n 
D 2 325 LEU 325 341 341 LEU LEU E . n 
D 2 326 VAL 326 342 342 VAL VAL E . n 
D 2 327 SER 327 343 343 SER SER E . n 
D 2 328 VAL 328 344 344 VAL VAL E . n 
D 2 329 PRO 329 345 345 PRO PRO E . n 
D 2 330 GLY 330 346 346 GLY GLY E . n 
D 2 331 LYS 331 347 347 LYS LYS E . n 
D 2 332 ASP 332 348 348 ASP ASP E . n 
D 2 333 ALA 333 349 349 ALA ALA E . n 
D 2 334 ILE 334 350 350 ILE ILE E . n 
D 2 335 TYR 335 351 351 TYR TYR E . n 
D 2 336 SER 336 352 352 SER SER E . n 
D 2 337 LEU 337 353 353 LEU LEU E . n 
D 2 338 GLY 338 354 354 GLY GLY E . n 
D 2 339 GLY 339 355 355 GLY GLY E . n 
D 2 340 LYS 340 356 356 LYS LYS E . n 
D 2 341 THR 341 357 357 THR THR E . n 
D 2 342 LEU 342 358 358 LEU LEU E . n 
D 2 343 GLN 343 359 359 GLN GLN E . n 
D 2 344 ASP 344 360 360 ASP ASP E . n 
D 2 345 THR 345 361 361 THR THR E . n 
D 2 346 LEU 346 362 362 LEU LEU E . n 
D 2 347 SER 347 363 363 SER SER E . n 
D 2 348 ASN 348 364 364 ASN ASN E . n 
D 2 349 ALA 349 365 365 ALA ALA E . n 
D 2 350 VAL 350 366 366 VAL VAL E . n 
D 2 351 ILE 351 367 367 ILE ILE E . n 
D 2 352 TYR 352 368 368 TYR TYR E . n 
D 2 353 TYR 353 369 369 TYR TYR E . n 
D 2 354 ARG 354 370 370 ARG ARG E . n 
D 2 355 VAL 355 371 371 VAL VAL E . n 
D 2 356 GLY 356 372 372 GLY GLY E . n 
D 2 357 ASP 357 373 373 ASP ASP E . n 
D 2 358 ASN 358 374 374 ASN ASN E . n 
D 2 359 VAL 359 375 375 VAL VAL E . n 
D 2 360 TRP 360 376 376 TRP TRP E . n 
D 2 361 THR 361 377 377 THR THR E . n 
D 2 362 GLU 362 378 378 GLU GLU E . n 
D 2 363 THR 363 379 379 THR THR E . n 
D 2 364 THR 364 380 380 THR THR E . n 
D 2 365 GLN 365 381 381 GLN GLN E . n 
D 2 366 LEU 366 382 382 LEU LEU E . n 
D 2 367 GLU 367 383 383 GLU GLU E . n 
D 2 368 VAL 368 384 384 VAL VAL E . n 
D 2 369 ALA 369 385 385 ALA ALA E . n 
D 2 370 VAL 370 386 386 VAL VAL E . n 
D 2 371 SER 371 387 387 SER SER E . n 
D 2 372 GLY 372 388 388 GLY GLY E . n 
D 2 373 ALA 373 389 389 ALA ALA E . n 
D 2 374 ALA 374 390 390 ALA ALA E . n 
D 2 375 GLY 375 391 391 GLY GLY E . n 
D 2 376 ALA 376 392 392 ALA ALA E . n 
D 2 377 ASN 377 393 393 ASN ASN E . n 
D 2 378 LEU 378 394 394 LEU LEU E . n 
D 2 379 ASN 379 395 395 ASN ASN E . n 
D 2 380 GLY 380 396 396 GLY GLY E . n 
D 2 381 ILE 381 397 397 ILE ILE E . n 
D 2 382 ILE 382 398 398 ILE ILE E . n 
D 2 383 TYR 383 399 399 TYR TYR E . n 
D 2 384 LEU 384 400 400 LEU LEU E . n 
D 2 385 LEU 385 401 401 LEU LEU E . n 
D 2 386 GLY 386 402 402 GLY GLY E . n 
D 2 387 GLY 387 403 403 GLY GLY E . n 
D 2 388 GLU 388 404 404 GLU GLU E . n 
D 2 389 GLU 389 405 405 GLU GLU E . n 
D 2 390 ASN 390 406 406 ASN ASN E . n 
D 2 391 ASP 391 407 407 ASP ASP E . n 
D 2 392 LEU 392 408 408 LEU LEU E . n 
D 2 393 ASP 393 409 409 ASP ASP E . n 
D 2 394 PHE 394 410 410 PHE PHE E . n 
D 2 395 PHE 395 411 411 PHE PHE E . n 
D 2 396 THR 396 412 412 THR THR E . n 
D 2 397 LYS 397 413 413 LYS LYS E . n 
D 2 398 PRO 398 414 414 PRO PRO E . n 
D 2 399 SER 399 415 415 SER SER E . n 
D 2 400 ARG 400 416 416 ARG ARG E . n 
D 2 401 LEU 401 417 417 LEU LEU E . n 
D 2 402 ILE 402 418 418 ILE ILE E . n 
D 2 403 GLN 403 419 419 GLN GLN E . n 
D 2 404 CYS 404 420 420 CYS CYS E . n 
D 2 405 PHE 405 421 421 PHE PHE E . n 
D 2 406 ASP 406 422 422 ASP ASP E . n 
D 2 407 THR 407 423 423 THR THR E . n 
D 2 408 GLU 408 424 424 GLU GLU E . n 
D 2 409 THR 409 425 425 THR THR E . n 
D 2 410 ASP 410 426 426 ASP ASP E . n 
D 2 411 LYS 411 427 427 LYS LYS E . n 
D 2 412 CYS 412 428 428 CYS CYS E . n 
D 2 413 HIS 413 429 429 HIS HIS E . n 
D 2 414 VAL 414 430 430 VAL VAL E . n 
D 2 415 LYS 415 431 431 LYS LYS E . n 
D 2 416 PRO 416 432 432 PRO PRO E . n 
D 2 417 TYR 417 433 433 TYR TYR E . n 
D 2 418 VAL 418 434 434 VAL VAL E . n 
D 2 419 LEU 419 435 435 LEU LEU E . n 
D 2 420 PRO 420 436 436 PRO PRO E . n 
D 2 421 PHE 421 437 437 PHE PHE E . n 
D 2 422 ALA 422 438 438 ALA ALA E . n 
D 2 423 GLY 423 439 439 GLY GLY E . n 
D 2 424 ARG 424 440 440 ARG ARG E . n 
D 2 425 MET 425 441 441 MET MET E . n 
D 2 426 HIS 426 442 442 HIS HIS E . n 
D 2 427 ALA 427 443 443 ALA ALA E . n 
D 2 428 ALA 428 444 444 ALA ALA E . n 
D 2 429 VAL 429 445 445 VAL VAL E . n 
D 2 430 HIS 430 446 446 HIS HIS E . n 
D 2 431 LYS 431 447 447 LYS LYS E . n 
D 2 432 ASP 432 448 448 ASP ASP E . n 
D 2 433 LEU 433 449 449 LEU LEU E . n 
D 2 434 VAL 434 450 450 VAL VAL E . n 
D 2 435 PHE 435 451 451 PHE PHE E . n 
D 2 436 ILE 436 452 452 ILE ILE E . n 
D 2 437 VAL 437 453 453 VAL VAL E . n 
D 2 438 ALA 438 454 454 ALA ALA E . n 
D 2 439 GLU 439 455 455 GLU GLU E . n 
D 2 440 GLY 440 456 456 GLY GLY E . n 
D 2 441 ASP 441 457 457 ASP ASP E . n 
D 2 442 SER 442 458 458 SER SER E . n 
D 2 443 LEU 443 459 459 LEU LEU E . n 
D 2 444 VAL 444 460 460 VAL VAL E . n 
D 2 445 CYS 445 461 461 CYS CYS E . n 
D 2 446 TYR 446 462 462 TYR TYR E . n 
D 2 447 ASN 447 463 463 ASN ASN E . n 
D 2 448 PRO 448 464 464 PRO PRO E . n 
D 2 449 LEU 449 465 465 LEU LEU E . n 
D 2 450 LEU 450 466 466 LEU LEU E . n 
D 2 451 ASP 451 467 467 ASP ASP E . n 
D 2 452 SER 452 468 468 SER SER E . n 
D 2 453 PHE 453 469 469 PHE PHE E . n 
D 2 454 THR 454 470 470 THR THR E . n 
D 2 455 ARG 455 471 471 ARG ARG E . n 
D 2 456 LEU 456 472 472 LEU LEU E . n 
D 2 457 CYS 457 473 473 CYS CYS E . n 
D 2 458 LEU 458 474 474 LEU LEU E . n 
D 2 459 PRO 459 475 475 PRO PRO E . n 
D 2 460 GLU 460 476 476 GLU GLU E . n 
D 2 461 ALA 461 477 477 ALA ALA E . n 
D 2 462 TRP 462 478 478 TRP TRP E . n 
D 2 463 SER 463 479 479 SER SER E . n 
D 2 464 SER 464 480 480 SER SER E . n 
D 2 465 ALA 465 481 481 ALA ALA E . n 
D 2 466 PRO 466 482 482 PRO PRO E . n 
D 2 467 SER 467 483 483 SER SER E . n 
D 2 468 LEU 468 484 484 LEU LEU E . n 
D 2 469 TRP 469 485 485 TRP TRP E . n 
D 2 470 LYS 470 486 486 LYS LYS E . n 
D 2 471 ILE 471 487 487 ILE ILE E . n 
D 2 472 ALA 472 488 488 ALA ALA E . n 
D 2 473 SER 473 489 489 SER SER E . n 
D 2 474 CYS 474 490 490 CYS CYS E . n 
D 2 475 ASN 475 491 491 ASN ASN E . n 
D 2 476 GLY 476 492 492 GLY GLY E . n 
D 2 477 SER 477 493 493 SER SER E . n 
D 2 478 ILE 478 494 494 ILE ILE E . n 
D 2 479 TYR 479 495 495 TYR TYR E . n 
D 2 480 VAL 480 496 496 VAL VAL E . n 
D 2 481 PHE 481 497 497 PHE PHE E . n 
D 2 482 ARG 482 498 498 ARG ARG E . n 
D 2 483 ASP 483 499 499 ASP ASP E . n 
D 2 484 ARG 484 500 500 ARG ARG E . n 
D 2 485 TYR 485 501 501 TYR TYR E . n 
D 2 486 LYS 486 502 502 LYS LYS E . n 
D 2 487 LYS 487 503 503 LYS LYS E . n 
D 2 488 GLY 488 504 504 GLY GLY E . n 
D 2 489 ASP 489 505 505 ASP ASP E . n 
D 2 490 ALA 490 506 506 ALA ALA E . n 
D 2 491 ASN 491 507 507 ASN ASN E . n 
D 2 492 THR 492 508 508 THR THR E . n 
D 2 493 TYR 493 509 509 TYR TYR E . n 
D 2 494 LYS 494 510 510 LYS LYS E . n 
D 2 495 LEU 495 511 511 LEU LEU E . n 
D 2 496 ASP 496 512 512 ASP ASP E . n 
D 2 497 PRO 497 513 513 PRO PRO E . n 
D 2 498 ALA 498 514 514 ALA ALA E . n 
D 2 499 THR 499 515 515 THR THR E . n 
D 2 500 SER 500 516 516 SER SER E . n 
D 2 501 ALA 501 517 517 ALA ALA E . n 
D 2 502 VAL 502 518 518 VAL VAL E . n 
D 2 503 THR 503 519 519 THR THR E . n 
D 2 504 VAL 504 520 520 VAL VAL E . n 
D 2 505 THR 505 521 521 THR THR E . n 
D 2 506 ARG 506 522 522 ARG ARG E . n 
D 2 507 GLY 507 523 523 GLY GLY E . n 
D 2 508 ILE 508 524 524 ILE ILE E . n 
D 2 509 LYS 509 525 525 LYS LYS E . n 
D 2 510 VAL 510 526 526 VAL VAL E . n 
D 2 511 LEU 511 527 527 LEU LEU E . n 
D 2 512 LEU 512 528 528 LEU LEU E . n 
D 2 513 THR 513 529 529 THR THR E . n 
D 2 514 ASN 514 530 530 ASN ASN E . n 
D 2 515 LEU 515 531 531 LEU LEU E . n 
D 2 516 GLN 516 532 532 GLN GLN E . n 
D 2 517 PHE 517 533 533 PHE PHE E . n 
D 2 518 VAL 518 534 534 VAL VAL E . n 
D 2 519 LEU 519 535 535 LEU LEU E . n 
D 2 520 ALA 520 536 536 ALA ALA E . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        IHP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   IHP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         E 
_pdbx_nonpoly_scheme.entity_id       4 
_pdbx_nonpoly_scheme.mon_id          IHP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    201 
_pdbx_nonpoly_scheme.pdb_mon_id      IHP 
_pdbx_nonpoly_scheme.auth_mon_id     IHP 
_pdbx_nonpoly_scheme.pdb_strand_id   D 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 D PHE 128 ? CE2 ? C PHE 148 CE2 
2 1 Y 1 D PHE 128 ? CZ  ? C PHE 148 CZ  
3 1 Y 1 D LYS 133 ? N   ? C LYS 153 N   
4 1 Y 1 D LYS 133 ? CA  ? C LYS 153 CA  
5 1 Y 1 D LYS 133 ? C   ? C LYS 153 C   
6 1 Y 1 D LYS 133 ? O   ? C LYS 153 O   
7 1 Y 1 D LYS 133 ? CB  ? C LYS 153 CB  
8 1 Y 1 D LYS 133 ? CG  ? C LYS 153 CG  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DTQ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DTQ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DTQ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9DTQ 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 12443 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.477 ? 16871 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 5.924 ? 1701  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.042 ? 1844  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 2170  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9DTQ 
_struct.title                        'The structure of HDAC2-CoREST in complex with KBTBD4R313PRR mutant' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DTQ 
_struct_keywords.text            'protein degradation, E3 ligase, Neo-substrate, cancer mutation, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 2 ? 
E N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP HDAC2_HUMAN Q92769 ? 1 
;AYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIR
PDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAI
LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQI
FKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVAL
DCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGED
PDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTK
SEQLSNP
;
2  
2 UNP KBTB4_HUMAN Q9NVX7 ? 2 
;MESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKE
AHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDP
ELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFAESLRTSLKEIGENVHI
YLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNATVDWEWCAPLPRDRLQ
HTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSRLI
QCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYVFR
DRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
17 
3 UNP RCOR1_HUMAN Q9UKL0 ? 3 
;SWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNME
QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSV
MDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVE
AVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDF
QAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVRYASAS

;
86 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9DTQ A 1 ? 487 ? Q92769 2  ? 488 ? 2   488 
2 2 9DTQ B 1 ? 520 ? Q9NVX7 17 ? 534 ? 17  536 
3 3 9DTQ D 2 ? 401 ? Q9UKL0 86 ? 485 ? -18 381 
4 2 9DTQ E 1 ? 520 ? Q9NVX7 17 ? 534 ? 17  536 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 9DTQ PRO B 295 ? UNP Q9NVX7 ? ? insertion               311 1 
2 9DTQ ARG B 296 ? UNP Q9NVX7 ? ? insertion               312 2 
3 9DTQ MET D 1   ? UNP Q9UKL0 ? ? 'initiating methionine' -19 3 
4 9DTQ PRO E 295 ? UNP Q9NVX7 ? ? insertion               311 4 
4 9DTQ ARG E 296 ? UNP Q9NVX7 ? ? insertion               312 5 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 18  ? TYR A 22  ? ASP A 19  TYR A 23  5 ? 5  
HELX_P HELX_P2  AA2 HIS A 33  ? TYR A 45  ? HIS A 34  TYR A 46  1 ? 13 
HELX_P HELX_P3  AA3 LEU A 47  ? MET A 51  ? LEU A 48  MET A 52  5 ? 5  
HELX_P HELX_P4  AA4 THR A 60  ? THR A 65  ? THR A 61  THR A 66  1 ? 6  
HELX_P HELX_P5  AA5 SER A 69  ? ILE A 79  ? SER A 70  ILE A 80  1 ? 11 
HELX_P HELX_P6  AA6 ARG A 80  ? MET A 84  ? ARG A 81  MET A 85  5 ? 5  
HELX_P HELX_P7  AA7 TYR A 87  ? ASN A 95  ? TYR A 88  ASN A 96  1 ? 9  
HELX_P HELX_P8  AA8 GLY A 105 ? ARG A 126 ? GLY A 106 ARG A 127 1 ? 22 
HELX_P HELX_P9  AA9 ASN A 154 ? LEU A 164 ? ASN A 155 LEU A 165 1 ? 11 
HELX_P HELX_P10 AB1 GLY A 180 ? PHE A 187 ? GLY A 181 PHE A 188 1 ? 8  
HELX_P HELX_P11 AB2 ALA A 216 ? LYS A 220 ? ALA A 217 LYS A 221 5 ? 5  
HELX_P HELX_P12 AB3 ASP A 233 ? GLN A 253 ? ASP A 234 GLN A 254 1 ? 21 
HELX_P HELX_P13 AB4 GLY A 262 ? LEU A 266 ? GLY A 263 LEU A 267 5 ? 5  
HELX_P HELX_P14 AB5 THR A 277 ? LYS A 289 ? THR A 278 LYS A 290 1 ? 13 
HELX_P HELX_P15 AB6 THR A 290 ? ASN A 292 ? THR A 291 ASN A 293 5 ? 3  
HELX_P HELX_P16 AB7 THR A 304 ? LEU A 320 ? THR A 305 LEU A 321 1 ? 17 
HELX_P HELX_P17 AB8 TYR A 333 ? GLY A 338 ? TYR A 334 GLY A 339 5 ? 6  
HELX_P HELX_P18 AB9 THR A 355 ? ARG A 371 ? THR A 356 ARG A 372 1 ? 17 
HELX_P HELX_P19 AC1 SER B 25  ? GLU B 40  ? SER B 41  GLU B 56  1 ? 16 
HELX_P HELX_P20 AC2 HIS B 59  ? SER B 67  ? HIS B 75  SER B 83  1 ? 9  
HELX_P HELX_P21 AC3 SER B 67  ? SER B 76  ? SER B 83  SER B 92  1 ? 10 
HELX_P HELX_P22 AC4 SER B 92  ? GLY B 106 ? SER B 108 GLY B 122 1 ? 15 
HELX_P HELX_P23 AC5 GLU B 114 ? GLN B 126 ? GLU B 130 GLN B 142 1 ? 13 
HELX_P HELX_P24 AC6 LEU B 127 ? THR B 141 ? LEU B 143 THR B 157 1 ? 15 
HELX_P HELX_P25 AC7 ASN B 146 ? HIS B 157 ? ASN B 162 HIS B 173 1 ? 12 
HELX_P HELX_P26 AC8 ASP B 159 ? HIS B 173 ? ASP B 175 HIS B 189 1 ? 15 
HELX_P HELX_P27 AC9 HIS B 173 ? GLN B 178 ? HIS B 189 GLN B 194 1 ? 6  
HELX_P HELX_P28 AD1 THR B 180 ? HIS B 185 ? THR B 196 HIS B 201 1 ? 6  
HELX_P HELX_P29 AD2 PRO B 187 ? ASP B 197 ? PRO B 203 ASP B 213 1 ? 11 
HELX_P HELX_P30 AD3 ASN B 204 ? ASN B 216 ? ASN B 220 ASN B 232 1 ? 13 
HELX_P HELX_P31 AD4 ARG B 220 ? ALA B 222 ? ARG B 236 ALA B 238 5 ? 3  
HELX_P HELX_P32 AD5 PHE B 223 ? SER B 230 ? PHE B 239 SER B 246 1 ? 8  
HELX_P HELX_P33 AD6 PRO B 459 ? SER B 463 ? PRO B 475 SER B 479 5 ? 5  
HELX_P HELX_P34 AD7 SER C 61  ? GLY C 77  ? SER D 41  GLY D 57  1 ? 17 
HELX_P HELX_P35 AD8 ASN C 79  ? HIS C 90  ? ASN D 59  HIS D 70  1 ? 12 
HELX_P HELX_P36 AD9 ILE C 94  ? ALA C 99  ? ILE D 74  ALA D 79  1 ? 6  
HELX_P HELX_P37 AE1 ASP C 100 ? PHE C 104 ? ASP D 80  PHE D 84  5 ? 5  
HELX_P HELX_P38 AE2 THR C 112 ? GLY C 127 ? THR D 92  GLY D 107 1 ? 16 
HELX_P HELX_P39 AE3 THR C 129 ? LEU C 137 ? THR D 109 LEU D 117 1 ? 9  
HELX_P HELX_P40 AE4 SER C 141 ? PHE C 148 ? SER D 121 PHE D 128 1 ? 8  
HELX_P HELX_P41 AE5 SER D 25  ? GLU D 40  ? SER E 41  GLU E 56  1 ? 16 
HELX_P HELX_P42 AE6 HIS D 59  ? SER D 67  ? HIS E 75  SER E 83  1 ? 9  
HELX_P HELX_P43 AE7 SER D 67  ? SER D 76  ? SER E 83  SER E 92  1 ? 10 
HELX_P HELX_P44 AE8 SER D 92  ? GLY D 106 ? SER E 108 GLY E 122 1 ? 15 
HELX_P HELX_P45 AE9 GLU D 114 ? TYR D 125 ? GLU E 130 TYR E 141 1 ? 12 
HELX_P HELX_P46 AF1 LEU D 127 ? THR D 141 ? LEU E 143 THR E 157 1 ? 15 
HELX_P HELX_P47 AF2 GLN D 143 ? GLY D 145 ? GLN E 159 GLY E 161 5 ? 3  
HELX_P HELX_P48 AF3 ASN D 146 ? HIS D 157 ? ASN E 162 HIS E 173 1 ? 12 
HELX_P HELX_P49 AF4 ASP D 159 ? HIS D 173 ? ASP E 175 HIS E 189 1 ? 15 
HELX_P HELX_P50 AF5 HIS D 173 ? ASN D 179 ? HIS E 189 ASN E 195 1 ? 7  
HELX_P HELX_P51 AF6 THR D 180 ? HIS D 185 ? THR E 196 HIS E 201 1 ? 6  
HELX_P HELX_P52 AF7 PRO D 187 ? ASP D 197 ? PRO E 203 ASP E 213 1 ? 11 
HELX_P HELX_P53 AF8 ASN D 204 ? ASN D 216 ? ASN E 220 ASN E 232 1 ? 13 
HELX_P HELX_P54 AF9 ASN D 216 ? GLU D 221 ? ASN E 232 GLU E 237 1 ? 6  
HELX_P HELX_P55 AG1 PHE D 223 ? LEU D 231 ? PHE E 239 LEU E 247 1 ? 9  
HELX_P HELX_P56 AG2 LEU D 392 ? PHE D 394 ? LEU E 408 PHE E 410 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 205 A . ? PHE 206 A PRO 206 A ? PRO 207 A 1 -2.28 
2 GLY 338 A . ? GLY 339 A PRO 339 A ? PRO 340 A 1 -2.33 
3 ILE 294 D . ? ILE 310 E PRO 295 D ? PRO 311 E 1 -2.70 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 9 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 2 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
AB5 ? 3 ? 
AB6 ? 2 ? 
AB7 ? 4 ? 
AB8 ? 3 ? 
AB9 ? 2 ? 
AC1 ? 4 ? 
AC2 ? 3 ? 
AC3 ? 4 ? 
AC4 ? 4 ? 
AC5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? parallel      
AA1 8 9 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? parallel      
AB6 1 2 ? parallel      
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 223 ? MET A 228 ? ALA A 224 MET A 229 
AA1 2 VAL A 193 ? LYS A 200 ? VAL A 194 LYS A 201 
AA1 3 VAL A 170 ? ASP A 174 ? VAL A 171 ASP A 175 
AA1 4 ALA A 256 ? GLN A 260 ? ALA A 257 GLN A 261 
AA1 5 LEU A 295 ? LEU A 298 ? LEU A 296 LEU A 299 
AA1 6 MET A 131 ? ASN A 134 ? MET A 132 ASN A 135 
AA1 7 VAL A 11  ? TYR A 14  ? VAL A 12  TYR A 15  
AA1 8 GLU A 52  ? ARG A 55  ? GLU A 53  ARG A 56  
AA1 9 MET C 51  ? TRP C 54  ? MET D 31  TRP D 34  
AA2 1 ASN B 18  ? LYS B 22  ? ASN B 34  LYS B 38  
AA2 2 THR D 107 ? ARG D 111 ? THR E 123 ARG E 127 
AA3 1 ARG B 54  ? LEU B 58  ? ARG B 70  LEU B 74  
AA3 2 VAL B 47  ? VAL B 51  ? VAL B 63  VAL B 67  
AA3 3 ILE B 86  ? LEU B 88  ? ILE B 102 LEU B 104 
AA4 1 THR B 107 ? ARG B 111 ? THR B 123 ARG B 127 
AA4 2 ASN D 18  ? LYS D 22  ? ASN E 34  LYS E 38  
AA5 1 VAL B 199 ? PRO B 200 ? VAL B 215 PRO B 216 
AA5 2 GLU B 233 ? ILE B 234 ? GLU B 249 ILE B 250 
AA6 1 ILE B 240 ? TYR B 241 ? ILE B 256 TYR B 257 
AA6 2 ALA B 254 ? CYS B 259 ? ALA B 270 CYS B 275 
AA6 3 ILE B 265 ? ASN B 271 ? ILE B 281 ASN B 287 
AA7 1 GLY B 244 ? GLU B 246 ? GLY B 260 GLU B 262 
AA7 2 LEU B 512 ? LEU B 515 ? LEU B 528 LEU B 531 
AA8 1 GLN B 276 ? CYS B 281 ? GLN B 292 CYS B 297 
AA8 2 LEU B 287 ? GLY B 292 ? LEU B 303 GLY B 308 
AA8 3 ARG B 299 ? CYS B 303 ? ARG B 315 CYS B 319 
AA8 4 GLU B 311 ? TRP B 312 ? GLU B 327 TRP B 328 
AA9 1 THR B 324 ? VAL B 328 ? THR B 340 VAL B 344 
AA9 2 ALA B 333 ? LYS B 340 ? ALA B 349 LYS B 356 
AA9 3 LEU B 346 ? ARG B 354 ? LEU B 362 ARG B 370 
AA9 4 VAL B 359 ? GLU B 362 ? VAL B 375 GLU B 378 
AB1 1 ALA B 374 ? ASN B 377 ? ALA B 390 ASN B 393 
AB1 2 ILE B 381 ? LEU B 385 ? ILE B 397 LEU B 401 
AB1 3 LEU B 401 ? ASP B 406 ? LEU B 417 ASP B 422 
AB1 4 LYS B 411 ? VAL B 418 ? LYS B 427 VAL B 434 
AB2 1 GLU B 388 ? ASN B 390 ? GLU B 404 ASN B 406 
AB2 2 THR B 396 ? PRO B 398 ? THR B 412 PRO B 414 
AB3 1 MET B 425 ? HIS B 430 ? MET B 441 HIS B 446 
AB3 2 LEU B 433 ? ALA B 438 ? LEU B 449 ALA B 454 
AB3 3 SER B 442 ? ASN B 447 ? SER B 458 ASN B 463 
AB3 4 SER B 452 ? CYS B 457 ? SER B 468 CYS B 473 
AB4 1 TRP B 469 ? CYS B 474 ? TRP B 485 CYS B 490 
AB4 2 SER B 477 ? ARG B 482 ? SER B 493 ARG B 498 
AB4 3 THR B 492 ? ASP B 496 ? THR B 508 ASP B 512 
AB4 4 ALA B 501 ? THR B 505 ? ALA B 517 THR B 521 
AB5 1 ARG D 54  ? LEU D 58  ? ARG E 70  LEU E 74  
AB5 2 VAL D 47  ? VAL D 51  ? VAL E 63  VAL E 67  
AB5 3 VAL D 85  ? VAL D 87  ? VAL E 101 VAL E 103 
AB6 1 VAL D 199 ? PRO D 200 ? VAL E 215 PRO E 216 
AB6 2 GLU D 233 ? ILE D 234 ? GLU E 249 ILE E 250 
AB7 1 ILE D 265 ? LEU D 273 ? ILE E 281 LEU E 289 
AB7 2 SER D 252 ? CYS D 259 ? SER E 268 CYS E 275 
AB7 3 HIS D 239 ? LYS D 245 ? HIS E 255 LYS E 261 
AB7 4 ASN D 514 ? LEU D 519 ? ASN E 530 LEU E 535 
AB8 1 ILE D 277 ? HIS D 283 ? ILE E 293 HIS E 299 
AB8 2 ASP D 286 ? SER D 293 ? ASP E 302 SER E 309 
AB8 3 ARG D 296 ? MET D 300 ? ARG E 312 MET E 316 
AB9 1 ARG D 320 ? LEU D 321 ? ARG E 336 LEU E 337 
AB9 2 LYS D 340 ? THR D 341 ? LYS E 356 THR E 357 
AC1 1 THR D 324 ? VAL D 328 ? THR E 340 VAL E 344 
AC1 2 ALA D 333 ? LEU D 337 ? ALA E 349 LEU E 353 
AC1 3 VAL D 350 ? ARG D 354 ? VAL E 366 ARG E 370 
AC1 4 VAL D 359 ? THR D 363 ? VAL E 375 THR E 379 
AC2 1 VAL D 370 ? SER D 371 ? VAL E 386 SER E 387 
AC2 2 GLU D 388 ? ASP D 391 ? GLU E 404 ASP E 407 
AC2 3 PHE D 395 ? PRO D 398 ? PHE E 411 PRO E 414 
AC3 1 ALA D 374 ? ASN D 377 ? ALA E 390 ASN E 393 
AC3 2 ILE D 381 ? LEU D 385 ? ILE E 397 LEU E 401 
AC3 3 ILE D 402 ? ASP D 406 ? ILE E 418 ASP E 422 
AC3 4 LYS D 411 ? VAL D 414 ? LYS E 427 VAL E 430 
AC4 1 HIS D 426 ? VAL D 429 ? HIS E 442 VAL E 445 
AC4 2 VAL D 434 ? VAL D 437 ? VAL E 450 VAL E 453 
AC4 3 SER D 442 ? ASN D 447 ? SER E 458 ASN E 463 
AC4 4 SER D 452 ? CYS D 457 ? SER E 468 CYS E 473 
AC5 1 TRP D 469 ? CYS D 474 ? TRP E 485 CYS E 490 
AC5 2 SER D 477 ? ARG D 482 ? SER E 493 ARG E 498 
AC5 3 THR D 492 ? ASP D 496 ? THR E 508 ASP E 512 
AC5 4 ALA D 501 ? VAL D 504 ? ALA E 517 VAL E 520 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O PHE A 226 ? O PHE A 227 N SER A 197 ? N SER A 198 
AA1 2 3 O VAL A 196 ? O VAL A 197 N TYR A 172 ? N TYR A 173 
AA1 3 4 N LEU A 171 ? N LEU A 172 O ALA A 256 ? O ALA A 257 
AA1 4 5 N LEU A 259 ? N LEU A 260 O LEU A 298 ? O LEU A 299 
AA1 5 6 O MET A 297 ? O MET A 298 N ALA A 132 ? N ALA A 133 
AA1 6 7 O VAL A 133 ? O VAL A 134 N CYS A 12  ? N CYS A 13  
AA1 7 8 N TYR A 13  ? N TYR A 14  O GLU A 52  ? O GLU A 53  
AA1 8 9 N ILE A 53  ? N ILE A 54  O VAL C 53  ? O VAL D 33  
AA2 1 2 N PHE B 21  ? N PHE B 37  O VAL D 108 ? O VAL E 124 
AA3 1 2 O PHE B 56  ? O PHE B 72  N ILE B 49  ? N ILE B 65  
AA3 2 3 N SER B 50  ? N SER B 66  O ILE B 86  ? O ILE B 102 
AA4 1 2 N VAL B 108 ? N VAL B 124 O PHE D 21  ? O PHE E 37  
AA5 1 2 N VAL B 199 ? N VAL B 215 O ILE B 234 ? O ILE B 250 
AA6 1 2 N ILE B 240 ? N ILE B 256 O LEU B 257 ? O LEU B 273 
AA6 2 3 N HIS B 258 ? N HIS B 274 O SER B 266 ? O SER B 282 
AA7 1 2 N LYS B 245 ? N LYS B 261 O ASN B 514 ? O ASN B 530 
AA8 1 2 N THR B 278 ? N THR B 294 O VAL B 290 ? O VAL B 306 
AA8 2 3 N GLY B 291 ? N GLY B 307 O ARG B 299 ? O ARG B 315 
AA8 3 4 N LYS B 302 ? N LYS B 318 O GLU B 311 ? O GLU B 327 
AA9 1 2 N VAL B 326 ? N VAL B 342 O TYR B 335 ? O TYR B 351 
AA9 2 3 N SER B 336 ? N SER B 352 O ILE B 351 ? O ILE B 367 
AA9 3 4 N TYR B 352 ? N TYR B 368 O THR B 361 ? O THR B 377 
AB1 1 2 N ALA B 376 ? N ALA B 392 O TYR B 383 ? O TYR B 399 
AB1 2 3 N LEU B 384 ? N LEU B 400 O GLN B 403 ? O GLN B 419 
AB1 3 4 N CYS B 404 ? N CYS B 420 O HIS B 413 ? O HIS B 429 
AB2 1 2 N GLU B 389 ? N GLU B 405 O LYS B 397 ? O LYS B 413 
AB3 1 2 N ALA B 428 ? N ALA B 444 O PHE B 435 ? O PHE B 451 
AB3 2 3 N VAL B 434 ? N VAL B 450 O TYR B 446 ? O TYR B 462 
AB3 3 4 N CYS B 445 ? N CYS B 461 O THR B 454 ? O THR B 470 
AB4 1 2 N LYS B 470 ? N LYS B 486 O PHE B 481 ? O PHE B 497 
AB4 2 3 N ILE B 478 ? N ILE B 494 O LEU B 495 ? O LEU B 511 
AB4 3 4 N THR B 492 ? N THR B 508 O THR B 505 ? O THR B 521 
AB5 1 2 O PHE D 56  ? O PHE E 72  N ILE D 49  ? N ILE E 65  
AB5 2 3 N SER D 50  ? N SER E 66  O ILE D 86  ? O ILE E 102 
AB6 1 2 N VAL D 199 ? N VAL E 215 O ILE D 234 ? O ILE E 250 
AB7 1 2 O LEU D 273 ? O LEU E 289 N SER D 252 ? N SER E 268 
AB7 2 3 O VAL D 255 ? O VAL E 271 N LEU D 242 ? N LEU E 258 
AB7 3 4 N TYR D 241 ? N TYR E 257 O LEU D 519 ? O LEU E 535 
AB8 1 2 N CYS D 281 ? N CYS E 297 O TYR D 288 ? O TYR E 304 
AB8 2 3 N SER D 293 ? N SER E 309 O ARG D 296 ? O ARG E 312 
AB9 1 2 N LEU D 321 ? N LEU E 337 O LYS D 340 ? O LYS E 356 
AC1 1 2 N VAL D 326 ? N VAL E 342 O TYR D 335 ? O TYR E 351 
AC1 2 3 N SER D 336 ? N SER E 352 O ILE D 351 ? O ILE E 367 
AC1 3 4 N TYR D 352 ? N TYR E 368 O THR D 361 ? O THR E 377 
AC2 1 2 N SER D 371 ? N SER E 387 O GLU D 388 ? O GLU E 404 
AC2 2 3 N GLU D 389 ? N GLU E 405 O LYS D 397 ? O LYS E 413 
AC3 1 2 N ALA D 376 ? N ALA E 392 O TYR D 383 ? O TYR E 399 
AC3 2 3 N LEU D 384 ? N LEU E 400 O GLN D 403 ? O GLN E 419 
AC3 3 4 N CYS D 404 ? N CYS E 420 O HIS D 413 ? O HIS E 429 
AC4 1 2 N ALA D 428 ? N ALA E 444 O PHE D 435 ? O PHE E 451 
AC4 2 3 N ILE D 436 ? N ILE E 452 O VAL D 444 ? O VAL E 460 
AC4 3 4 N LEU D 443 ? N LEU E 459 O LEU D 456 ? O LEU E 472 
AC5 1 2 N LYS D 470 ? N LYS E 486 O PHE D 481 ? O PHE E 497 
AC5 2 3 N ILE D 478 ? N ILE E 494 O LEU D 495 ? O LEU E 511 
AC5 3 4 N LYS D 494 ? N LYS E 510 O THR D 503 ? O THR E 519 
# 
_pdbx_entry_details.entry_id                   9DTQ 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 CE  D LYS 133 ? ? O26 D IHP 401 ? ? 1.38 
2 1 CA  A GLY 28  ? ? O34 D IHP 401 ? ? 1.38 
3 1 N   A GLY 28  ? ? O34 D IHP 401 ? ? 1.59 
4 1 OD2 A ASP 235 ? ? OG1 A THR 278 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR B 31  ? ? -69.48  2.05    
2  1 VAL B 33  ? ? -124.57 -57.29  
3  1 ASN B 99  ? ? -79.83  -70.04  
4  1 ARG B 100 ? ? -136.50 -40.31  
5  1 PHE B 410 ? ? 58.83   14.53   
6  1 LYS B 447 ? ? 59.03   -126.28 
7  1 ASN B 491 ? ? 37.20   59.25   
8  1 PRO D 12  ? ? -69.60  -177.46 
9  1 ALA D 20  ? ? -95.35  55.66   
10 1 SER D 23  ? ? -88.55  47.07   
11 1 GLU D 25  ? ? -151.50 -159.26 
12 1 ARG D 26  ? ? 78.86   -85.02  
13 1 ASP D 27  ? ? -162.38 117.06  
14 1 GLU D 54  ? ? -92.32  46.31   
15 1 LYS D 55  ? ? -132.37 -39.08  
16 1 HIS D 56  ? ? -140.54 13.62   
17 1 HIS D 70  ? ? -93.78  49.00   
18 1 VAL E 33  ? ? -123.32 -59.92  
19 1 THR E 91  ? ? -62.85  -71.44  
20 1 SER E 92  ? ? 32.88   51.36   
21 1 ASN E 93  ? ? -69.44  70.47   
22 1 ASN E 162 ? ? -140.32 14.82   
23 1 PRO E 311 ? ? -100.71 42.14   
24 1 VAL E 324 ? ? 35.16   50.31   
25 1 GLU E 327 ? ? -89.01  49.62   
26 1 LEU E 408 ? ? 54.86   71.15   
27 1 ASP E 409 ? ? -67.12  58.86   
28 1 LYS E 525 ? ? -96.87  58.75   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   LEU 
_pdbx_validate_peptide_omega.auth_asym_id_1   E 
_pdbx_validate_peptide_omega.auth_seq_id_1    408 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   ASP 
_pdbx_validate_peptide_omega.auth_asym_id_2   E 
_pdbx_validate_peptide_omega.auth_seq_id_2    409 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -135.69 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    E 
_pdbx_validate_planes.auth_seq_id     471 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.186 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9DTQ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9DTQ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.87 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               700385 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 LHC-KBTBD4PRRmutant 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        9DTQ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9DTQ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9DTQ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A ALA 2   ? A ALA 1   
2   1 Y 1 A TYR 3   ? A TYR 2   
3   1 Y 1 A SER 4   ? A SER 3   
4   1 Y 1 A GLN 5   ? A GLN 4   
5   1 Y 1 A GLY 6   ? A GLY 5   
6   1 Y 1 A GLY 7   ? A GLY 6   
7   1 Y 1 A GLY 8   ? A GLY 7   
8   1 Y 1 A HIS 376 ? A HIS 375 
9   1 Y 1 A ALA 377 ? A ALA 376 
10  1 Y 1 A PRO 378 ? A PRO 377 
11  1 Y 1 A GLY 379 ? A GLY 378 
12  1 Y 1 A VAL 380 ? A VAL 379 
13  1 Y 1 A GLN 381 ? A GLN 380 
14  1 Y 1 A MET 382 ? A MET 381 
15  1 Y 1 A GLN 383 ? A GLN 382 
16  1 Y 1 A ALA 384 ? A ALA 383 
17  1 Y 1 A ILE 385 ? A ILE 384 
18  1 Y 1 A PRO 386 ? A PRO 385 
19  1 Y 1 A GLU 387 ? A GLU 386 
20  1 Y 1 A ASP 388 ? A ASP 387 
21  1 Y 1 A ALA 389 ? A ALA 388 
22  1 Y 1 A VAL 390 ? A VAL 389 
23  1 Y 1 A HIS 391 ? A HIS 390 
24  1 Y 1 A GLU 392 ? A GLU 391 
25  1 Y 1 A ASP 393 ? A ASP 392 
26  1 Y 1 A SER 394 ? A SER 393 
27  1 Y 1 A GLY 395 ? A GLY 394 
28  1 Y 1 A ASP 396 ? A ASP 395 
29  1 Y 1 A GLU 397 ? A GLU 396 
30  1 Y 1 A ASP 398 ? A ASP 397 
31  1 Y 1 A GLY 399 ? A GLY 398 
32  1 Y 1 A GLU 400 ? A GLU 399 
33  1 Y 1 A ASP 401 ? A ASP 400 
34  1 Y 1 A PRO 402 ? A PRO 401 
35  1 Y 1 A ASP 403 ? A ASP 402 
36  1 Y 1 A LYS 404 ? A LYS 403 
37  1 Y 1 A ARG 405 ? A ARG 404 
38  1 Y 1 A ILE 406 ? A ILE 405 
39  1 Y 1 A SER 407 ? A SER 406 
40  1 Y 1 A ILE 408 ? A ILE 407 
41  1 Y 1 A ARG 409 ? A ARG 408 
42  1 Y 1 A ALA 410 ? A ALA 409 
43  1 Y 1 A SER 411 ? A SER 410 
44  1 Y 1 A ASP 412 ? A ASP 411 
45  1 Y 1 A LYS 413 ? A LYS 412 
46  1 Y 1 A ARG 414 ? A ARG 413 
47  1 Y 1 A ILE 415 ? A ILE 414 
48  1 Y 1 A ALA 416 ? A ALA 415 
49  1 Y 1 A CYS 417 ? A CYS 416 
50  1 Y 1 A ASP 418 ? A ASP 417 
51  1 Y 1 A GLU 419 ? A GLU 418 
52  1 Y 1 A GLU 420 ? A GLU 419 
53  1 Y 1 A PHE 421 ? A PHE 420 
54  1 Y 1 A SER 422 ? A SER 421 
55  1 Y 1 A ASP 423 ? A ASP 422 
56  1 Y 1 A SER 424 ? A SER 423 
57  1 Y 1 A GLU 425 ? A GLU 424 
58  1 Y 1 A ASP 426 ? A ASP 425 
59  1 Y 1 A GLU 427 ? A GLU 426 
60  1 Y 1 A GLY 428 ? A GLY 427 
61  1 Y 1 A GLU 429 ? A GLU 428 
62  1 Y 1 A GLY 430 ? A GLY 429 
63  1 Y 1 A GLY 431 ? A GLY 430 
64  1 Y 1 A ARG 432 ? A ARG 431 
65  1 Y 1 A ARG 433 ? A ARG 432 
66  1 Y 1 A ASN 434 ? A ASN 433 
67  1 Y 1 A VAL 435 ? A VAL 434 
68  1 Y 1 A ALA 436 ? A ALA 435 
69  1 Y 1 A ASP 437 ? A ASP 436 
70  1 Y 1 A HIS 438 ? A HIS 437 
71  1 Y 1 A LYS 439 ? A LYS 438 
72  1 Y 1 A LYS 440 ? A LYS 439 
73  1 Y 1 A GLY 441 ? A GLY 440 
74  1 Y 1 A ALA 442 ? A ALA 441 
75  1 Y 1 A LYS 443 ? A LYS 442 
76  1 Y 1 A LYS 444 ? A LYS 443 
77  1 Y 1 A ALA 445 ? A ALA 444 
78  1 Y 1 A ARG 446 ? A ARG 445 
79  1 Y 1 A ILE 447 ? A ILE 446 
80  1 Y 1 A GLU 448 ? A GLU 447 
81  1 Y 1 A GLU 449 ? A GLU 448 
82  1 Y 1 A ASP 450 ? A ASP 449 
83  1 Y 1 A LYS 451 ? A LYS 450 
84  1 Y 1 A LYS 452 ? A LYS 451 
85  1 Y 1 A GLU 453 ? A GLU 452 
86  1 Y 1 A THR 454 ? A THR 453 
87  1 Y 1 A GLU 455 ? A GLU 454 
88  1 Y 1 A ASP 456 ? A ASP 455 
89  1 Y 1 A LYS 457 ? A LYS 456 
90  1 Y 1 A LYS 458 ? A LYS 457 
91  1 Y 1 A THR 459 ? A THR 458 
92  1 Y 1 A ASP 460 ? A ASP 459 
93  1 Y 1 A VAL 461 ? A VAL 460 
94  1 Y 1 A LYS 462 ? A LYS 461 
95  1 Y 1 A GLU 463 ? A GLU 462 
96  1 Y 1 A GLU 464 ? A GLU 463 
97  1 Y 1 A ASP 465 ? A ASP 464 
98  1 Y 1 A LYS 466 ? A LYS 465 
99  1 Y 1 A SER 467 ? A SER 466 
100 1 Y 1 A LYS 468 ? A LYS 467 
101 1 Y 1 A ASP 469 ? A ASP 468 
102 1 Y 1 A ASN 470 ? A ASN 469 
103 1 Y 1 A SER 471 ? A SER 470 
104 1 Y 1 A GLY 472 ? A GLY 471 
105 1 Y 1 A GLU 473 ? A GLU 472 
106 1 Y 1 A LYS 474 ? A LYS 473 
107 1 Y 1 A THR 475 ? A THR 474 
108 1 Y 1 A ASP 476 ? A ASP 475 
109 1 Y 1 A THR 477 ? A THR 476 
110 1 Y 1 A LYS 478 ? A LYS 477 
111 1 Y 1 A GLY 479 ? A GLY 478 
112 1 Y 1 A THR 480 ? A THR 479 
113 1 Y 1 A LYS 481 ? A LYS 480 
114 1 Y 1 A SER 482 ? A SER 481 
115 1 Y 1 A GLU 483 ? A GLU 482 
116 1 Y 1 A GLN 484 ? A GLN 483 
117 1 Y 1 A LEU 485 ? A LEU 484 
118 1 Y 1 A SER 486 ? A SER 485 
119 1 Y 1 A ASN 487 ? A ASN 486 
120 1 Y 1 A PRO 488 ? A PRO 487 
121 1 Y 1 B MET 17  ? B MET 1   
122 1 Y 1 B GLU 18  ? B GLU 2   
123 1 Y 1 B SER 19  ? B SER 3   
124 1 Y 1 B PRO 20  ? B PRO 4   
125 1 Y 1 B GLU 21  ? B GLU 5   
126 1 Y 1 B GLU 22  ? B GLU 6   
127 1 Y 1 B PRO 23  ? B PRO 7   
128 1 Y 1 B GLY 24  ? B GLY 8   
129 1 Y 1 B ALA 25  ? B ALA 9   
130 1 Y 1 D MET -19 ? C MET 1   
131 1 Y 1 D SER -18 ? C SER 2   
132 1 Y 1 D TRP -17 ? C TRP 3   
133 1 Y 1 D GLU -16 ? C GLU 4   
134 1 Y 1 D GLU -15 ? C GLU 5   
135 1 Y 1 D GLY -14 ? C GLY 6   
136 1 Y 1 D SER -13 ? C SER 7   
137 1 Y 1 D SER -12 ? C SER 8   
138 1 Y 1 D GLY -11 ? C GLY 9   
139 1 Y 1 D SER -10 ? C SER 10  
140 1 Y 1 D SER -9  ? C SER 11  
141 1 Y 1 D SER -8  ? C SER 12  
142 1 Y 1 D ASP -7  ? C ASP 13  
143 1 Y 1 D GLU -6  ? C GLU 14  
144 1 Y 1 D GLU -5  ? C GLU 15  
145 1 Y 1 D HIS -4  ? C HIS 16  
146 1 Y 1 D GLY -3  ? C GLY 17  
147 1 Y 1 D GLY -2  ? C GLY 18  
148 1 Y 1 D GLY -1  ? C GLY 19  
149 1 Y 1 D GLY 0   ? C GLY 20  
150 1 Y 1 D TYR 129 ? C TYR 149 
151 1 Y 1 D TYR 130 ? C TYR 150 
152 1 Y 1 D SER 131 ? C SER 151 
153 1 Y 1 D TRP 132 ? C TRP 152 
154 1 Y 1 D ARG 136 ? C ARG 156 
155 1 Y 1 D THR 137 ? C THR 157 
156 1 Y 1 D LYS 138 ? C LYS 158 
157 1 Y 1 D THR 139 ? C THR 159 
158 1 Y 1 D SER 140 ? C SER 160 
159 1 Y 1 D VAL 141 ? C VAL 161 
160 1 Y 1 D MET 142 ? C MET 162 
161 1 Y 1 D ASP 143 ? C ASP 163 
162 1 Y 1 D ARG 144 ? C ARG 164 
163 1 Y 1 D HIS 145 ? C HIS 165 
164 1 Y 1 D ALA 146 ? C ALA 166 
165 1 Y 1 D ARG 147 ? C ARG 167 
166 1 Y 1 D LYS 148 ? C LYS 168 
167 1 Y 1 D GLN 149 ? C GLN 169 
168 1 Y 1 D LYS 150 ? C LYS 170 
169 1 Y 1 D ARG 151 ? C ARG 171 
170 1 Y 1 D GLU 152 ? C GLU 172 
171 1 Y 1 D ARG 153 ? C ARG 173 
172 1 Y 1 D GLU 154 ? C GLU 174 
173 1 Y 1 D GLU 155 ? C GLU 175 
174 1 Y 1 D SER 156 ? C SER 176 
175 1 Y 1 D GLU 157 ? C GLU 177 
176 1 Y 1 D ASP 158 ? C ASP 178 
177 1 Y 1 D GLU 159 ? C GLU 179 
178 1 Y 1 D LEU 160 ? C LEU 180 
179 1 Y 1 D GLU 161 ? C GLU 181 
180 1 Y 1 D GLU 162 ? C GLU 182 
181 1 Y 1 D ALA 163 ? C ALA 183 
182 1 Y 1 D ASN 164 ? C ASN 184 
183 1 Y 1 D GLY 165 ? C GLY 185 
184 1 Y 1 D ASN 166 ? C ASN 186 
185 1 Y 1 D ASN 167 ? C ASN 187 
186 1 Y 1 D PRO 168 ? C PRO 188 
187 1 Y 1 D ILE 169 ? C ILE 189 
188 1 Y 1 D ASP 170 ? C ASP 190 
189 1 Y 1 D ILE 171 ? C ILE 191 
190 1 Y 1 D GLU 172 ? C GLU 192 
191 1 Y 1 D VAL 173 ? C VAL 193 
192 1 Y 1 D ASP 174 ? C ASP 194 
193 1 Y 1 D GLN 175 ? C GLN 195 
194 1 Y 1 D ASN 176 ? C ASN 196 
195 1 Y 1 D LYS 177 ? C LYS 197 
196 1 Y 1 D GLU 178 ? C GLU 198 
197 1 Y 1 D SER 179 ? C SER 199 
198 1 Y 1 D LYS 180 ? C LYS 200 
199 1 Y 1 D LYS 181 ? C LYS 201 
200 1 Y 1 D GLU 182 ? C GLU 202 
201 1 Y 1 D VAL 183 ? C VAL 203 
202 1 Y 1 D PRO 184 ? C PRO 204 
203 1 Y 1 D PRO 185 ? C PRO 205 
204 1 Y 1 D THR 186 ? C THR 206 
205 1 Y 1 D GLU 187 ? C GLU 207 
206 1 Y 1 D THR 188 ? C THR 208 
207 1 Y 1 D VAL 189 ? C VAL 209 
208 1 Y 1 D PRO 190 ? C PRO 210 
209 1 Y 1 D GLN 191 ? C GLN 211 
210 1 Y 1 D VAL 192 ? C VAL 212 
211 1 Y 1 D LYS 193 ? C LYS 213 
212 1 Y 1 D LYS 194 ? C LYS 214 
213 1 Y 1 D GLU 195 ? C GLU 215 
214 1 Y 1 D LYS 196 ? C LYS 216 
215 1 Y 1 D HIS 197 ? C HIS 217 
216 1 Y 1 D SER 198 ? C SER 218 
217 1 Y 1 D THR 199 ? C THR 219 
218 1 Y 1 D GLN 200 ? C GLN 220 
219 1 Y 1 D ALA 201 ? C ALA 221 
220 1 Y 1 D LYS 202 ? C LYS 222 
221 1 Y 1 D ASN 203 ? C ASN 223 
222 1 Y 1 D ARG 204 ? C ARG 224 
223 1 Y 1 D ALA 205 ? C ALA 225 
224 1 Y 1 D LYS 206 ? C LYS 226 
225 1 Y 1 D ARG 207 ? C ARG 227 
226 1 Y 1 D LYS 208 ? C LYS 228 
227 1 Y 1 D PRO 209 ? C PRO 229 
228 1 Y 1 D PRO 210 ? C PRO 230 
229 1 Y 1 D LYS 211 ? C LYS 231 
230 1 Y 1 D GLY 212 ? C GLY 232 
231 1 Y 1 D MET 213 ? C MET 233 
232 1 Y 1 D PHE 214 ? C PHE 234 
233 1 Y 1 D LEU 215 ? C LEU 235 
234 1 Y 1 D SER 216 ? C SER 236 
235 1 Y 1 D GLN 217 ? C GLN 237 
236 1 Y 1 D GLU 218 ? C GLU 238 
237 1 Y 1 D ASP 219 ? C ASP 239 
238 1 Y 1 D VAL 220 ? C VAL 240 
239 1 Y 1 D GLU 221 ? C GLU 241 
240 1 Y 1 D ALA 222 ? C ALA 242 
241 1 Y 1 D VAL 223 ? C VAL 243 
242 1 Y 1 D SER 224 ? C SER 244 
243 1 Y 1 D ALA 225 ? C ALA 245 
244 1 Y 1 D ASN 226 ? C ASN 246 
245 1 Y 1 D ALA 227 ? C ALA 247 
246 1 Y 1 D THR 228 ? C THR 248 
247 1 Y 1 D ALA 229 ? C ALA 249 
248 1 Y 1 D ALA 230 ? C ALA 250 
249 1 Y 1 D THR 231 ? C THR 251 
250 1 Y 1 D THR 232 ? C THR 252 
251 1 Y 1 D VAL 233 ? C VAL 253 
252 1 Y 1 D LEU 234 ? C LEU 254 
253 1 Y 1 D ARG 235 ? C ARG 255 
254 1 Y 1 D GLN 236 ? C GLN 256 
255 1 Y 1 D LEU 237 ? C LEU 257 
256 1 Y 1 D ASP 238 ? C ASP 258 
257 1 Y 1 D MET 239 ? C MET 259 
258 1 Y 1 D GLU 240 ? C GLU 260 
259 1 Y 1 D LEU 241 ? C LEU 261 
260 1 Y 1 D VAL 242 ? C VAL 262 
261 1 Y 1 D SER 243 ? C SER 263 
262 1 Y 1 D VAL 244 ? C VAL 264 
263 1 Y 1 D LYS 245 ? C LYS 265 
264 1 Y 1 D ARG 246 ? C ARG 266 
265 1 Y 1 D GLN 247 ? C GLN 267 
266 1 Y 1 D ILE 248 ? C ILE 268 
267 1 Y 1 D GLN 249 ? C GLN 269 
268 1 Y 1 D ASN 250 ? C ASN 270 
269 1 Y 1 D ILE 251 ? C ILE 271 
270 1 Y 1 D LYS 252 ? C LYS 272 
271 1 Y 1 D GLN 253 ? C GLN 273 
272 1 Y 1 D THR 254 ? C THR 274 
273 1 Y 1 D ASN 255 ? C ASN 275 
274 1 Y 1 D SER 256 ? C SER 276 
275 1 Y 1 D ALA 257 ? C ALA 277 
276 1 Y 1 D LEU 258 ? C LEU 278 
277 1 Y 1 D LYS 259 ? C LYS 279 
278 1 Y 1 D GLU 260 ? C GLU 280 
279 1 Y 1 D LYS 261 ? C LYS 281 
280 1 Y 1 D LEU 262 ? C LEU 282 
281 1 Y 1 D ASP 263 ? C ASP 283 
282 1 Y 1 D GLY 264 ? C GLY 284 
283 1 Y 1 D GLY 265 ? C GLY 285 
284 1 Y 1 D ILE 266 ? C ILE 286 
285 1 Y 1 D GLU 267 ? C GLU 287 
286 1 Y 1 D PRO 268 ? C PRO 288 
287 1 Y 1 D TYR 269 ? C TYR 289 
288 1 Y 1 D ARG 270 ? C ARG 290 
289 1 Y 1 D LEU 271 ? C LEU 291 
290 1 Y 1 D PRO 272 ? C PRO 292 
291 1 Y 1 D GLU 273 ? C GLU 293 
292 1 Y 1 D VAL 274 ? C VAL 294 
293 1 Y 1 D ILE 275 ? C ILE 295 
294 1 Y 1 D GLN 276 ? C GLN 296 
295 1 Y 1 D LYS 277 ? C LYS 297 
296 1 Y 1 D CYS 278 ? C CYS 298 
297 1 Y 1 D ASN 279 ? C ASN 299 
298 1 Y 1 D ALA 280 ? C ALA 300 
299 1 Y 1 D ARG 281 ? C ARG 301 
300 1 Y 1 D TRP 282 ? C TRP 302 
301 1 Y 1 D THR 283 ? C THR 303 
302 1 Y 1 D THR 284 ? C THR 304 
303 1 Y 1 D GLU 285 ? C GLU 305 
304 1 Y 1 D GLU 286 ? C GLU 306 
305 1 Y 1 D GLN 287 ? C GLN 307 
306 1 Y 1 D LEU 288 ? C LEU 308 
307 1 Y 1 D LEU 289 ? C LEU 309 
308 1 Y 1 D ALA 290 ? C ALA 310 
309 1 Y 1 D VAL 291 ? C VAL 311 
310 1 Y 1 D GLN 292 ? C GLN 312 
311 1 Y 1 D ALA 293 ? C ALA 313 
312 1 Y 1 D ILE 294 ? C ILE 314 
313 1 Y 1 D ARG 295 ? C ARG 315 
314 1 Y 1 D LYS 296 ? C LYS 316 
315 1 Y 1 D TYR 297 ? C TYR 317 
316 1 Y 1 D GLY 298 ? C GLY 318 
317 1 Y 1 D ARG 299 ? C ARG 319 
318 1 Y 1 D ASP 300 ? C ASP 320 
319 1 Y 1 D PHE 301 ? C PHE 321 
320 1 Y 1 D GLN 302 ? C GLN 322 
321 1 Y 1 D ALA 303 ? C ALA 323 
322 1 Y 1 D ILE 304 ? C ILE 324 
323 1 Y 1 D SER 305 ? C SER 325 
324 1 Y 1 D ASP 306 ? C ASP 326 
325 1 Y 1 D VAL 307 ? C VAL 327 
326 1 Y 1 D ILE 308 ? C ILE 328 
327 1 Y 1 D GLY 309 ? C GLY 329 
328 1 Y 1 D ASN 310 ? C ASN 330 
329 1 Y 1 D LYS 311 ? C LYS 331 
330 1 Y 1 D SER 312 ? C SER 332 
331 1 Y 1 D VAL 313 ? C VAL 333 
332 1 Y 1 D VAL 314 ? C VAL 334 
333 1 Y 1 D GLN 315 ? C GLN 335 
334 1 Y 1 D VAL 316 ? C VAL 336 
335 1 Y 1 D LYS 317 ? C LYS 337 
336 1 Y 1 D ASN 318 ? C ASN 338 
337 1 Y 1 D PHE 319 ? C PHE 339 
338 1 Y 1 D PHE 320 ? C PHE 340 
339 1 Y 1 D VAL 321 ? C VAL 341 
340 1 Y 1 D ASN 322 ? C ASN 342 
341 1 Y 1 D TYR 323 ? C TYR 343 
342 1 Y 1 D ARG 324 ? C ARG 344 
343 1 Y 1 D ARG 325 ? C ARG 345 
344 1 Y 1 D ARG 326 ? C ARG 346 
345 1 Y 1 D PHE 327 ? C PHE 347 
346 1 Y 1 D ASN 328 ? C ASN 348 
347 1 Y 1 D ILE 329 ? C ILE 349 
348 1 Y 1 D ASP 330 ? C ASP 350 
349 1 Y 1 D GLU 331 ? C GLU 351 
350 1 Y 1 D VAL 332 ? C VAL 352 
351 1 Y 1 D LEU 333 ? C LEU 353 
352 1 Y 1 D GLN 334 ? C GLN 354 
353 1 Y 1 D GLU 335 ? C GLU 355 
354 1 Y 1 D TRP 336 ? C TRP 356 
355 1 Y 1 D GLU 337 ? C GLU 357 
356 1 Y 1 D ALA 338 ? C ALA 358 
357 1 Y 1 D GLU 339 ? C GLU 359 
358 1 Y 1 D HIS 340 ? C HIS 360 
359 1 Y 1 D GLY 341 ? C GLY 361 
360 1 Y 1 D LYS 342 ? C LYS 362 
361 1 Y 1 D GLU 343 ? C GLU 363 
362 1 Y 1 D GLU 344 ? C GLU 364 
363 1 Y 1 D THR 345 ? C THR 365 
364 1 Y 1 D ASN 346 ? C ASN 366 
365 1 Y 1 D GLY 347 ? C GLY 367 
366 1 Y 1 D PRO 348 ? C PRO 368 
367 1 Y 1 D SER 349 ? C SER 369 
368 1 Y 1 D ASN 350 ? C ASN 370 
369 1 Y 1 D GLN 351 ? C GLN 371 
370 1 Y 1 D LYS 352 ? C LYS 372 
371 1 Y 1 D PRO 353 ? C PRO 373 
372 1 Y 1 D VAL 354 ? C VAL 374 
373 1 Y 1 D LYS 355 ? C LYS 375 
374 1 Y 1 D SER 356 ? C SER 376 
375 1 Y 1 D PRO 357 ? C PRO 377 
376 1 Y 1 D ASP 358 ? C ASP 378 
377 1 Y 1 D ASN 359 ? C ASN 379 
378 1 Y 1 D SER 360 ? C SER 380 
379 1 Y 1 D ILE 361 ? C ILE 381 
380 1 Y 1 D LYS 362 ? C LYS 382 
381 1 Y 1 D MET 363 ? C MET 383 
382 1 Y 1 D PRO 364 ? C PRO 384 
383 1 Y 1 D GLU 365 ? C GLU 385 
384 1 Y 1 D GLU 366 ? C GLU 386 
385 1 Y 1 D GLU 367 ? C GLU 387 
386 1 Y 1 D ASP 368 ? C ASP 388 
387 1 Y 1 D GLU 369 ? C GLU 389 
388 1 Y 1 D ALA 370 ? C ALA 390 
389 1 Y 1 D PRO 371 ? C PRO 391 
390 1 Y 1 D VAL 372 ? C VAL 392 
391 1 Y 1 D LEU 373 ? C LEU 393 
392 1 Y 1 D ASP 374 ? C ASP 394 
393 1 Y 1 D VAL 375 ? C VAL 395 
394 1 Y 1 D ARG 376 ? C ARG 396 
395 1 Y 1 D TYR 377 ? C TYR 397 
396 1 Y 1 D ALA 378 ? C ALA 398 
397 1 Y 1 D SER 379 ? C SER 399 
398 1 Y 1 D ALA 380 ? C ALA 400 
399 1 Y 1 D SER 381 ? C SER 401 
400 1 Y 1 E MET 17  ? D MET 1   
401 1 Y 1 E GLU 18  ? D GLU 2   
402 1 Y 1 E SER 19  ? D SER 3   
403 1 Y 1 E PRO 20  ? D PRO 4   
404 1 Y 1 E GLU 21  ? D GLU 5   
405 1 Y 1 E GLU 22  ? D GLU 6   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
IHP C1   C N N 158 
IHP C2   C N N 159 
IHP C3   C N N 160 
IHP C4   C N N 161 
IHP C5   C N N 162 
IHP C6   C N N 163 
IHP O11  O N N 164 
IHP P1   P N N 165 
IHP O21  O N N 166 
IHP O31  O N N 167 
IHP O41  O N N 168 
IHP O12  O N N 169 
IHP P2   P N N 170 
IHP O22  O N N 171 
IHP O32  O N N 172 
IHP O42  O N N 173 
IHP O13  O N N 174 
IHP P3   P N N 175 
IHP O23  O N N 176 
IHP O33  O N N 177 
IHP O43  O N N 178 
IHP O14  O N N 179 
IHP P4   P N N 180 
IHP O24  O N N 181 
IHP O34  O N N 182 
IHP O44  O N N 183 
IHP O15  O N N 184 
IHP P5   P N N 185 
IHP O25  O N N 186 
IHP O35  O N N 187 
IHP O45  O N N 188 
IHP O16  O N N 189 
IHP P6   P N N 190 
IHP O26  O N N 191 
IHP O36  O N N 192 
IHP O46  O N N 193 
IHP H1   H N N 194 
IHP H2   H N N 195 
IHP H3   H N N 196 
IHP H4   H N N 197 
IHP H5   H N N 198 
IHP H6   H N N 199 
IHP H31  H N N 200 
IHP H41  H N N 201 
IHP H32  H N N 202 
IHP H42  H N N 203 
IHP H33  H N N 204 
IHP H43  H N N 205 
IHP H34  H N N 206 
IHP H44  H N N 207 
IHP H35  H N N 208 
IHP H45  H N N 209 
IHP H36  H N N 210 
IHP H46  H N N 211 
ILE N    N N N 212 
ILE CA   C N S 213 
ILE C    C N N 214 
ILE O    O N N 215 
ILE CB   C N S 216 
ILE CG1  C N N 217 
ILE CG2  C N N 218 
ILE CD1  C N N 219 
ILE OXT  O N N 220 
ILE H    H N N 221 
ILE H2   H N N 222 
ILE HA   H N N 223 
ILE HB   H N N 224 
ILE HG12 H N N 225 
ILE HG13 H N N 226 
ILE HG21 H N N 227 
ILE HG22 H N N 228 
ILE HG23 H N N 229 
ILE HD11 H N N 230 
ILE HD12 H N N 231 
ILE HD13 H N N 232 
ILE HXT  H N N 233 
LEU N    N N N 234 
LEU CA   C N S 235 
LEU C    C N N 236 
LEU O    O N N 237 
LEU CB   C N N 238 
LEU CG   C N N 239 
LEU CD1  C N N 240 
LEU CD2  C N N 241 
LEU OXT  O N N 242 
LEU H    H N N 243 
LEU H2   H N N 244 
LEU HA   H N N 245 
LEU HB2  H N N 246 
LEU HB3  H N N 247 
LEU HG   H N N 248 
LEU HD11 H N N 249 
LEU HD12 H N N 250 
LEU HD13 H N N 251 
LEU HD21 H N N 252 
LEU HD22 H N N 253 
LEU HD23 H N N 254 
LEU HXT  H N N 255 
LYS N    N N N 256 
LYS CA   C N S 257 
LYS C    C N N 258 
LYS O    O N N 259 
LYS CB   C N N 260 
LYS CG   C N N 261 
LYS CD   C N N 262 
LYS CE   C N N 263 
LYS NZ   N N N 264 
LYS OXT  O N N 265 
LYS H    H N N 266 
LYS H2   H N N 267 
LYS HA   H N N 268 
LYS HB2  H N N 269 
LYS HB3  H N N 270 
LYS HG2  H N N 271 
LYS HG3  H N N 272 
LYS HD2  H N N 273 
LYS HD3  H N N 274 
LYS HE2  H N N 275 
LYS HE3  H N N 276 
LYS HZ1  H N N 277 
LYS HZ2  H N N 278 
LYS HZ3  H N N 279 
LYS HXT  H N N 280 
MET N    N N N 281 
MET CA   C N S 282 
MET C    C N N 283 
MET O    O N N 284 
MET CB   C N N 285 
MET CG   C N N 286 
MET SD   S N N 287 
MET CE   C N N 288 
MET OXT  O N N 289 
MET H    H N N 290 
MET H2   H N N 291 
MET HA   H N N 292 
MET HB2  H N N 293 
MET HB3  H N N 294 
MET HG2  H N N 295 
MET HG3  H N N 296 
MET HE1  H N N 297 
MET HE2  H N N 298 
MET HE3  H N N 299 
MET HXT  H N N 300 
PHE N    N N N 301 
PHE CA   C N S 302 
PHE C    C N N 303 
PHE O    O N N 304 
PHE CB   C N N 305 
PHE CG   C Y N 306 
PHE CD1  C Y N 307 
PHE CD2  C Y N 308 
PHE CE1  C Y N 309 
PHE CE2  C Y N 310 
PHE CZ   C Y N 311 
PHE OXT  O N N 312 
PHE H    H N N 313 
PHE H2   H N N 314 
PHE HA   H N N 315 
PHE HB2  H N N 316 
PHE HB3  H N N 317 
PHE HD1  H N N 318 
PHE HD2  H N N 319 
PHE HE1  H N N 320 
PHE HE2  H N N 321 
PHE HZ   H N N 322 
PHE HXT  H N N 323 
PRO N    N N N 324 
PRO CA   C N S 325 
PRO C    C N N 326 
PRO O    O N N 327 
PRO CB   C N N 328 
PRO CG   C N N 329 
PRO CD   C N N 330 
PRO OXT  O N N 331 
PRO H    H N N 332 
PRO HA   H N N 333 
PRO HB2  H N N 334 
PRO HB3  H N N 335 
PRO HG2  H N N 336 
PRO HG3  H N N 337 
PRO HD2  H N N 338 
PRO HD3  H N N 339 
PRO HXT  H N N 340 
SER N    N N N 341 
SER CA   C N S 342 
SER C    C N N 343 
SER O    O N N 344 
SER CB   C N N 345 
SER OG   O N N 346 
SER OXT  O N N 347 
SER H    H N N 348 
SER H2   H N N 349 
SER HA   H N N 350 
SER HB2  H N N 351 
SER HB3  H N N 352 
SER HG   H N N 353 
SER HXT  H N N 354 
THR N    N N N 355 
THR CA   C N S 356 
THR C    C N N 357 
THR O    O N N 358 
THR CB   C N R 359 
THR OG1  O N N 360 
THR CG2  C N N 361 
THR OXT  O N N 362 
THR H    H N N 363 
THR H2   H N N 364 
THR HA   H N N 365 
THR HB   H N N 366 
THR HG1  H N N 367 
THR HG21 H N N 368 
THR HG22 H N N 369 
THR HG23 H N N 370 
THR HXT  H N N 371 
TRP N    N N N 372 
TRP CA   C N S 373 
TRP C    C N N 374 
TRP O    O N N 375 
TRP CB   C N N 376 
TRP CG   C Y N 377 
TRP CD1  C Y N 378 
TRP CD2  C Y N 379 
TRP NE1  N Y N 380 
TRP CE2  C Y N 381 
TRP CE3  C Y N 382 
TRP CZ2  C Y N 383 
TRP CZ3  C Y N 384 
TRP CH2  C Y N 385 
TRP OXT  O N N 386 
TRP H    H N N 387 
TRP H2   H N N 388 
TRP HA   H N N 389 
TRP HB2  H N N 390 
TRP HB3  H N N 391 
TRP HD1  H N N 392 
TRP HE1  H N N 393 
TRP HE3  H N N 394 
TRP HZ2  H N N 395 
TRP HZ3  H N N 396 
TRP HH2  H N N 397 
TRP HXT  H N N 398 
TYR N    N N N 399 
TYR CA   C N S 400 
TYR C    C N N 401 
TYR O    O N N 402 
TYR CB   C N N 403 
TYR CG   C Y N 404 
TYR CD1  C Y N 405 
TYR CD2  C Y N 406 
TYR CE1  C Y N 407 
TYR CE2  C Y N 408 
TYR CZ   C Y N 409 
TYR OH   O N N 410 
TYR OXT  O N N 411 
TYR H    H N N 412 
TYR H2   H N N 413 
TYR HA   H N N 414 
TYR HB2  H N N 415 
TYR HB3  H N N 416 
TYR HD1  H N N 417 
TYR HD2  H N N 418 
TYR HE1  H N N 419 
TYR HE2  H N N 420 
TYR HH   H N N 421 
TYR HXT  H N N 422 
VAL N    N N N 423 
VAL CA   C N S 424 
VAL C    C N N 425 
VAL O    O N N 426 
VAL CB   C N N 427 
VAL CG1  C N N 428 
VAL CG2  C N N 429 
VAL OXT  O N N 430 
VAL H    H N N 431 
VAL H2   H N N 432 
VAL HA   H N N 433 
VAL HB   H N N 434 
VAL HG11 H N N 435 
VAL HG12 H N N 436 
VAL HG13 H N N 437 
VAL HG21 H N N 438 
VAL HG22 H N N 439 
VAL HG23 H N N 440 
VAL HXT  H N N 441 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
IHP C1  C2   sing N N 150 
IHP C1  C6   sing N N 151 
IHP C1  O11  sing N N 152 
IHP C1  H1   sing N N 153 
IHP C2  C3   sing N N 154 
IHP C2  O12  sing N N 155 
IHP C2  H2   sing N N 156 
IHP C3  C4   sing N N 157 
IHP C3  O13  sing N N 158 
IHP C3  H3   sing N N 159 
IHP C4  C5   sing N N 160 
IHP C4  O14  sing N N 161 
IHP C4  H4   sing N N 162 
IHP C5  C6   sing N N 163 
IHP C5  O15  sing N N 164 
IHP C5  H5   sing N N 165 
IHP C6  O16  sing N N 166 
IHP C6  H6   sing N N 167 
IHP O11 P1   sing N N 168 
IHP P1  O21  doub N N 169 
IHP P1  O31  sing N N 170 
IHP P1  O41  sing N N 171 
IHP O31 H31  sing N N 172 
IHP O41 H41  sing N N 173 
IHP O12 P2   sing N N 174 
IHP P2  O22  doub N N 175 
IHP P2  O32  sing N N 176 
IHP P2  O42  sing N N 177 
IHP O32 H32  sing N N 178 
IHP O42 H42  sing N N 179 
IHP O13 P3   sing N N 180 
IHP P3  O23  doub N N 181 
IHP P3  O33  sing N N 182 
IHP P3  O43  sing N N 183 
IHP O33 H33  sing N N 184 
IHP O43 H43  sing N N 185 
IHP O14 P4   sing N N 186 
IHP P4  O24  doub N N 187 
IHP P4  O34  sing N N 188 
IHP P4  O44  sing N N 189 
IHP O34 H34  sing N N 190 
IHP O44 H44  sing N N 191 
IHP O15 P5   sing N N 192 
IHP P5  O25  doub N N 193 
IHP P5  O35  sing N N 194 
IHP P5  O45  sing N N 195 
IHP O35 H35  sing N N 196 
IHP O45 H45  sing N N 197 
IHP O16 P6   sing N N 198 
IHP P6  O26  doub N N 199 
IHP P6  O36  sing N N 200 
IHP P6  O46  sing N N 201 
IHP O36 H36  sing N N 202 
IHP O46 H46  sing N N 203 
ILE N   CA   sing N N 204 
ILE N   H    sing N N 205 
ILE N   H2   sing N N 206 
ILE CA  C    sing N N 207 
ILE CA  CB   sing N N 208 
ILE CA  HA   sing N N 209 
ILE C   O    doub N N 210 
ILE C   OXT  sing N N 211 
ILE CB  CG1  sing N N 212 
ILE CB  CG2  sing N N 213 
ILE CB  HB   sing N N 214 
ILE CG1 CD1  sing N N 215 
ILE CG1 HG12 sing N N 216 
ILE CG1 HG13 sing N N 217 
ILE CG2 HG21 sing N N 218 
ILE CG2 HG22 sing N N 219 
ILE CG2 HG23 sing N N 220 
ILE CD1 HD11 sing N N 221 
ILE CD1 HD12 sing N N 222 
ILE CD1 HD13 sing N N 223 
ILE OXT HXT  sing N N 224 
LEU N   CA   sing N N 225 
LEU N   H    sing N N 226 
LEU N   H2   sing N N 227 
LEU CA  C    sing N N 228 
LEU CA  CB   sing N N 229 
LEU CA  HA   sing N N 230 
LEU C   O    doub N N 231 
LEU C   OXT  sing N N 232 
LEU CB  CG   sing N N 233 
LEU CB  HB2  sing N N 234 
LEU CB  HB3  sing N N 235 
LEU CG  CD1  sing N N 236 
LEU CG  CD2  sing N N 237 
LEU CG  HG   sing N N 238 
LEU CD1 HD11 sing N N 239 
LEU CD1 HD12 sing N N 240 
LEU CD1 HD13 sing N N 241 
LEU CD2 HD21 sing N N 242 
LEU CD2 HD22 sing N N 243 
LEU CD2 HD23 sing N N 244 
LEU OXT HXT  sing N N 245 
LYS N   CA   sing N N 246 
LYS N   H    sing N N 247 
LYS N   H2   sing N N 248 
LYS CA  C    sing N N 249 
LYS CA  CB   sing N N 250 
LYS CA  HA   sing N N 251 
LYS C   O    doub N N 252 
LYS C   OXT  sing N N 253 
LYS CB  CG   sing N N 254 
LYS CB  HB2  sing N N 255 
LYS CB  HB3  sing N N 256 
LYS CG  CD   sing N N 257 
LYS CG  HG2  sing N N 258 
LYS CG  HG3  sing N N 259 
LYS CD  CE   sing N N 260 
LYS CD  HD2  sing N N 261 
LYS CD  HD3  sing N N 262 
LYS CE  NZ   sing N N 263 
LYS CE  HE2  sing N N 264 
LYS CE  HE3  sing N N 265 
LYS NZ  HZ1  sing N N 266 
LYS NZ  HZ2  sing N N 267 
LYS NZ  HZ3  sing N N 268 
LYS OXT HXT  sing N N 269 
MET N   CA   sing N N 270 
MET N   H    sing N N 271 
MET N   H2   sing N N 272 
MET CA  C    sing N N 273 
MET CA  CB   sing N N 274 
MET CA  HA   sing N N 275 
MET C   O    doub N N 276 
MET C   OXT  sing N N 277 
MET CB  CG   sing N N 278 
MET CB  HB2  sing N N 279 
MET CB  HB3  sing N N 280 
MET CG  SD   sing N N 281 
MET CG  HG2  sing N N 282 
MET CG  HG3  sing N N 283 
MET SD  CE   sing N N 284 
MET CE  HE1  sing N N 285 
MET CE  HE2  sing N N 286 
MET CE  HE3  sing N N 287 
MET OXT HXT  sing N N 288 
PHE N   CA   sing N N 289 
PHE N   H    sing N N 290 
PHE N   H2   sing N N 291 
PHE CA  C    sing N N 292 
PHE CA  CB   sing N N 293 
PHE CA  HA   sing N N 294 
PHE C   O    doub N N 295 
PHE C   OXT  sing N N 296 
PHE CB  CG   sing N N 297 
PHE CB  HB2  sing N N 298 
PHE CB  HB3  sing N N 299 
PHE CG  CD1  doub Y N 300 
PHE CG  CD2  sing Y N 301 
PHE CD1 CE1  sing Y N 302 
PHE CD1 HD1  sing N N 303 
PHE CD2 CE2  doub Y N 304 
PHE CD2 HD2  sing N N 305 
PHE CE1 CZ   doub Y N 306 
PHE CE1 HE1  sing N N 307 
PHE CE2 CZ   sing Y N 308 
PHE CE2 HE2  sing N N 309 
PHE CZ  HZ   sing N N 310 
PHE OXT HXT  sing N N 311 
PRO N   CA   sing N N 312 
PRO N   CD   sing N N 313 
PRO N   H    sing N N 314 
PRO CA  C    sing N N 315 
PRO CA  CB   sing N N 316 
PRO CA  HA   sing N N 317 
PRO C   O    doub N N 318 
PRO C   OXT  sing N N 319 
PRO CB  CG   sing N N 320 
PRO CB  HB2  sing N N 321 
PRO CB  HB3  sing N N 322 
PRO CG  CD   sing N N 323 
PRO CG  HG2  sing N N 324 
PRO CG  HG3  sing N N 325 
PRO CD  HD2  sing N N 326 
PRO CD  HD3  sing N N 327 
PRO OXT HXT  sing N N 328 
SER N   CA   sing N N 329 
SER N   H    sing N N 330 
SER N   H2   sing N N 331 
SER CA  C    sing N N 332 
SER CA  CB   sing N N 333 
SER CA  HA   sing N N 334 
SER C   O    doub N N 335 
SER C   OXT  sing N N 336 
SER CB  OG   sing N N 337 
SER CB  HB2  sing N N 338 
SER CB  HB3  sing N N 339 
SER OG  HG   sing N N 340 
SER OXT HXT  sing N N 341 
THR N   CA   sing N N 342 
THR N   H    sing N N 343 
THR N   H2   sing N N 344 
THR CA  C    sing N N 345 
THR CA  CB   sing N N 346 
THR CA  HA   sing N N 347 
THR C   O    doub N N 348 
THR C   OXT  sing N N 349 
THR CB  OG1  sing N N 350 
THR CB  CG2  sing N N 351 
THR CB  HB   sing N N 352 
THR OG1 HG1  sing N N 353 
THR CG2 HG21 sing N N 354 
THR CG2 HG22 sing N N 355 
THR CG2 HG23 sing N N 356 
THR OXT HXT  sing N N 357 
TRP N   CA   sing N N 358 
TRP N   H    sing N N 359 
TRP N   H2   sing N N 360 
TRP CA  C    sing N N 361 
TRP CA  CB   sing N N 362 
TRP CA  HA   sing N N 363 
TRP C   O    doub N N 364 
TRP C   OXT  sing N N 365 
TRP CB  CG   sing N N 366 
TRP CB  HB2  sing N N 367 
TRP CB  HB3  sing N N 368 
TRP CG  CD1  doub Y N 369 
TRP CG  CD2  sing Y N 370 
TRP CD1 NE1  sing Y N 371 
TRP CD1 HD1  sing N N 372 
TRP CD2 CE2  doub Y N 373 
TRP CD2 CE3  sing Y N 374 
TRP NE1 CE2  sing Y N 375 
TRP NE1 HE1  sing N N 376 
TRP CE2 CZ2  sing Y N 377 
TRP CE3 CZ3  doub Y N 378 
TRP CE3 HE3  sing N N 379 
TRP CZ2 CH2  doub Y N 380 
TRP CZ2 HZ2  sing N N 381 
TRP CZ3 CH2  sing Y N 382 
TRP CZ3 HZ3  sing N N 383 
TRP CH2 HH2  sing N N 384 
TRP OXT HXT  sing N N 385 
TYR N   CA   sing N N 386 
TYR N   H    sing N N 387 
TYR N   H2   sing N N 388 
TYR CA  C    sing N N 389 
TYR CA  CB   sing N N 390 
TYR CA  HA   sing N N 391 
TYR C   O    doub N N 392 
TYR C   OXT  sing N N 393 
TYR CB  CG   sing N N 394 
TYR CB  HB2  sing N N 395 
TYR CB  HB3  sing N N 396 
TYR CG  CD1  doub Y N 397 
TYR CG  CD2  sing Y N 398 
TYR CD1 CE1  sing Y N 399 
TYR CD1 HD1  sing N N 400 
TYR CD2 CE2  doub Y N 401 
TYR CD2 HD2  sing N N 402 
TYR CE1 CZ   doub Y N 403 
TYR CE1 HE1  sing N N 404 
TYR CE2 CZ   sing Y N 405 
TYR CE2 HE2  sing N N 406 
TYR CZ  OH   sing N N 407 
TYR OH  HH   sing N N 408 
TYR OXT HXT  sing N N 409 
VAL N   CA   sing N N 410 
VAL N   H    sing N N 411 
VAL N   H2   sing N N 412 
VAL CA  C    sing N N 413 
VAL CA  CB   sing N N 414 
VAL CA  HA   sing N N 415 
VAL C   O    doub N N 416 
VAL C   OXT  sing N N 417 
VAL CB  CG1  sing N N 418 
VAL CB  CG2  sing N N 419 
VAL CB  HB   sing N N 420 
VAL CG1 HG11 sing N N 421 
VAL CG1 HG12 sing N N 422 
VAL CG1 HG13 sing N N 423 
VAL CG2 HG21 sing N N 424 
VAL CG2 HG22 sing N N 425 
VAL CG2 HG23 sing N N 426 
VAL OXT HXT  sing N N 427 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-01 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9DTQ 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'The structure of HDAC2-CoREST in complex with KBTBD4R313PRR mutant' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.21_5207: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?          
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?          
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?          
CLASSIFICATION                  ? 5  1 1 1 ?      ?          
MASKING                         ? 6  1 1 1 ?      ?          
RECONSTRUCTION                  ? 7  1 1 1 ?      ?          
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?          
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?          
'CTF CORRECTION'                ? 10 1 1 1 ?      ?          
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?          
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?          
'MODEL FITTING'                 ? 13 1 1 1 ?      ?          
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?          
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?          
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?          
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?          
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?          
OTHER                           ? 19 1 1 1 ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Howard Hughes Medical Institute (HHMI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9DTQ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . LYS A 1 8   ? 188.175 140.140 117.268 1.00 61.41  ? 9   LYS A N   1 
ATOM   2     C CA  . LYS A 1 8   ? 187.716 140.324 115.897 1.00 62.83  ? 9   LYS A CA  1 
ATOM   3     C C   . LYS A 1 8   ? 186.339 139.701 115.694 1.00 55.85  ? 9   LYS A C   1 
ATOM   4     O O   . LYS A 1 8   ? 186.125 138.942 114.751 1.00 54.40  ? 9   LYS A O   1 
ATOM   5     C CB  . LYS A 1 8   ? 188.719 139.722 114.912 1.00 68.10  ? 9   LYS A CB  1 
ATOM   6     C CG  . LYS A 1 8   ? 189.986 140.543 114.743 1.00 76.34  ? 9   LYS A CG  1 
ATOM   7     C CD  . LYS A 1 8   ? 190.909 139.934 113.700 1.00 80.38  ? 9   LYS A CD  1 
ATOM   8     C CE  . LYS A 1 8   ? 192.177 140.756 113.539 1.00 88.92  ? 9   LYS A CE  1 
ATOM   9     N NZ  . LYS A 1 8   ? 193.121 140.141 112.564 1.00 95.14  ? 9   LYS A NZ  1 
ATOM   10    N N   . LYS A 1 9   ? 185.410 140.026 116.589 1.00 49.52  ? 10  LYS A N   1 
ATOM   11    C CA  . LYS A 1 9   ? 184.054 139.514 116.498 1.00 45.27  ? 10  LYS A CA  1 
ATOM   12    C C   . LYS A 1 9   ? 183.262 140.275 115.437 1.00 42.72  ? 10  LYS A C   1 
ATOM   13    O O   . LYS A 1 9   ? 183.736 141.244 114.838 1.00 43.68  ? 10  LYS A O   1 
ATOM   14    C CB  . LYS A 1 9   ? 183.353 139.608 117.853 1.00 43.48  ? 10  LYS A CB  1 
ATOM   15    C CG  . LYS A 1 9   ? 183.859 138.621 118.890 1.00 45.08  ? 10  LYS A CG  1 
ATOM   16    C CD  . LYS A 1 9   ? 183.699 139.171 120.297 1.00 44.97  ? 10  LYS A CD  1 
ATOM   17    C CE  . LYS A 1 9   ? 184.963 138.968 121.116 1.00 46.27  ? 10  LYS A CE  1 
ATOM   18    N NZ  . LYS A 1 9   ? 184.804 139.440 122.519 1.00 36.60  ? 10  LYS A NZ  1 
ATOM   19    N N   . LYS A 1 10  ? 182.035 139.821 115.207 1.00 36.38  ? 11  LYS A N   1 
ATOM   20    C CA  . LYS A 1 10  ? 181.137 140.429 114.237 1.00 31.94  ? 11  LYS A CA  1 
ATOM   21    C C   . LYS A 1 10  ? 180.011 141.149 114.967 1.00 26.89  ? 11  LYS A C   1 
ATOM   22    O O   . LYS A 1 10  ? 179.376 140.576 115.857 1.00 24.36  ? 11  LYS A O   1 
ATOM   23    C CB  . LYS A 1 10  ? 180.569 139.373 113.290 1.00 30.87  ? 11  LYS A CB  1 
ATOM   24    C CG  . LYS A 1 10  ? 179.698 139.932 112.182 1.00 31.16  ? 11  LYS A CG  1 
ATOM   25    C CD  . LYS A 1 10  ? 179.362 138.862 111.161 1.00 35.77  ? 11  LYS A CD  1 
ATOM   26    C CE  . LYS A 1 10  ? 178.144 139.246 110.342 1.00 40.12  ? 11  LYS A CE  1 
ATOM   27    N NZ  . LYS A 1 10  ? 177.666 138.114 109.501 1.00 42.95  ? 11  LYS A NZ  1 
ATOM   28    N N   . VAL A 1 11  ? 179.770 142.403 114.588 1.00 26.60  ? 12  VAL A N   1 
ATOM   29    C CA  . VAL A 1 11  ? 178.754 143.245 115.206 1.00 21.83  ? 12  VAL A CA  1 
ATOM   30    C C   . VAL A 1 11  ? 177.737 143.636 114.144 1.00 19.10  ? 12  VAL A C   1 
ATOM   31    O O   . VAL A 1 11  ? 178.106 144.004 113.025 1.00 20.50  ? 12  VAL A O   1 
ATOM   32    C CB  . VAL A 1 11  ? 179.371 144.501 115.859 1.00 18.87  ? 12  VAL A CB  1 
ATOM   33    C CG1 . VAL A 1 11  ? 178.359 145.187 116.759 1.00 15.61  ? 12  VAL A CG1 1 
ATOM   34    C CG2 . VAL A 1 11  ? 180.618 144.138 116.641 1.00 21.35  ? 12  VAL A CG2 1 
ATOM   35    N N   . CYS A 1 12  ? 176.456 143.541 114.494 1.00 16.37  ? 13  CYS A N   1 
ATOM   36    C CA  . CYS A 1 12  ? 175.361 143.925 113.617 1.00 14.28  ? 13  CYS A CA  1 
ATOM   37    C C   . CYS A 1 12  ? 174.630 145.118 114.214 1.00 15.29  ? 13  CYS A C   1 
ATOM   38    O O   . CYS A 1 12  ? 174.490 145.223 115.436 1.00 15.72  ? 13  CYS A O   1 
ATOM   39    C CB  . CYS A 1 12  ? 174.384 142.768 113.400 1.00 16.07  ? 13  CYS A CB  1 
ATOM   40    S SG  . CYS A 1 12  ? 175.036 141.426 112.387 1.00 36.10  ? 13  CYS A SG  1 
ATOM   41    N N   . TYR A 1 13  ? 174.169 146.016 113.348 1.00 15.38  ? 14  TYR A N   1 
ATOM   42    C CA  . TYR A 1 13  ? 173.547 147.266 113.759 1.00 12.48  ? 14  TYR A CA  1 
ATOM   43    C C   . TYR A 1 13  ? 172.201 147.403 113.069 1.00 14.76  ? 14  TYR A C   1 
ATOM   44    O O   . TYR A 1 13  ? 172.110 147.259 111.847 1.00 17.22  ? 14  TYR A O   1 
ATOM   45    C CB  . TYR A 1 13  ? 174.453 148.454 113.418 1.00 14.59  ? 14  TYR A CB  1 
ATOM   46    C CG  . TYR A 1 13  ? 173.950 149.805 113.875 1.00 14.90  ? 14  TYR A CG  1 
ATOM   47    C CD1 . TYR A 1 13  ? 173.928 150.142 115.220 1.00 11.71  ? 14  TYR A CD1 1 
ATOM   48    C CD2 . TYR A 1 13  ? 173.523 150.754 112.956 1.00 16.52  ? 14  TYR A CD2 1 
ATOM   49    C CE1 . TYR A 1 13  ? 173.479 151.377 115.636 1.00 13.39  ? 14  TYR A CE1 1 
ATOM   50    C CE2 . TYR A 1 13  ? 173.073 151.991 113.363 1.00 13.85  ? 14  TYR A CE2 1 
ATOM   51    C CZ  . TYR A 1 13  ? 173.053 152.299 114.703 1.00 13.71  ? 14  TYR A CZ  1 
ATOM   52    O OH  . TYR A 1 13  ? 172.606 153.532 115.113 1.00 13.95  ? 14  TYR A OH  1 
ATOM   53    N N   . TYR A 1 14  ? 171.161 147.679 113.851 1.00 15.20  ? 15  TYR A N   1 
ATOM   54    C CA  . TYR A 1 14  ? 169.806 147.837 113.343 1.00 14.59  ? 15  TYR A CA  1 
ATOM   55    C C   . TYR A 1 14  ? 169.359 149.274 113.559 1.00 18.05  ? 15  TYR A C   1 
ATOM   56    O O   . TYR A 1 14  ? 169.461 149.799 114.672 1.00 18.96  ? 15  TYR A O   1 
ATOM   57    C CB  . TYR A 1 14  ? 168.844 146.866 114.030 1.00 12.53  ? 15  TYR A CB  1 
ATOM   58    C CG  . TYR A 1 14  ? 169.146 145.419 113.724 1.00 14.87  ? 15  TYR A CG  1 
ATOM   59    C CD1 . TYR A 1 14  ? 170.099 144.720 114.453 1.00 16.21  ? 15  TYR A CD1 1 
ATOM   60    C CD2 . TYR A 1 14  ? 168.493 144.756 112.699 1.00 15.10  ? 15  TYR A CD2 1 
ATOM   61    C CE1 . TYR A 1 14  ? 170.389 143.404 114.172 1.00 14.82  ? 15  TYR A CE1 1 
ATOM   62    C CE2 . TYR A 1 14  ? 168.775 143.440 112.411 1.00 16.10  ? 15  TYR A CE2 1 
ATOM   63    C CZ  . TYR A 1 14  ? 169.724 142.770 113.150 1.00 17.54  ? 15  TYR A CZ  1 
ATOM   64    O OH  . TYR A 1 14  ? 170.007 141.456 112.864 1.00 23.19  ? 15  TYR A OH  1 
ATOM   65    N N   . TYR A 1 15  ? 168.872 149.906 112.493 1.00 18.32  ? 16  TYR A N   1 
ATOM   66    C CA  . TYR A 1 15  ? 168.463 151.302 112.560 1.00 17.30  ? 16  TYR A CA  1 
ATOM   67    C C   . TYR A 1 15  ? 167.455 151.578 111.457 1.00 23.37  ? 16  TYR A C   1 
ATOM   68    O O   . TYR A 1 15  ? 167.666 151.179 110.309 1.00 27.37  ? 16  TYR A O   1 
ATOM   69    C CB  . TYR A 1 15  ? 169.669 152.233 112.424 1.00 14.78  ? 16  TYR A CB  1 
ATOM   70    C CG  . TYR A 1 15  ? 169.314 153.700 112.391 1.00 16.94  ? 16  TYR A CG  1 
ATOM   71    C CD1 . TYR A 1 15  ? 168.922 154.365 113.541 1.00 17.08  ? 16  TYR A CD1 1 
ATOM   72    C CD2 . TYR A 1 15  ? 169.379 154.421 111.210 1.00 17.81  ? 16  TYR A CD2 1 
ATOM   73    C CE1 . TYR A 1 15  ? 168.599 155.704 113.514 1.00 15.26  ? 16  TYR A CE1 1 
ATOM   74    C CE2 . TYR A 1 15  ? 169.058 155.760 111.174 1.00 19.93  ? 16  TYR A CE2 1 
ATOM   75    C CZ  . TYR A 1 15  ? 168.671 156.396 112.329 1.00 16.93  ? 16  TYR A CZ  1 
ATOM   76    O OH  . TYR A 1 15  ? 168.350 157.731 112.297 1.00 17.49  ? 16  TYR A OH  1 
ATOM   77    N N   . ASP A 1 16  ? 166.367 152.256 111.809 1.00 24.37  ? 17  ASP A N   1 
ATOM   78    C CA  . ASP A 1 16  ? 165.372 152.716 110.852 1.00 24.42  ? 17  ASP A CA  1 
ATOM   79    C C   . ASP A 1 16  ? 165.375 154.238 110.829 1.00 24.02  ? 17  ASP A C   1 
ATOM   80    O O   . ASP A 1 16  ? 165.290 154.878 111.881 1.00 24.75  ? 17  ASP A O   1 
ATOM   81    C CB  . ASP A 1 16  ? 163.983 152.189 111.206 1.00 30.36  ? 17  ASP A CB  1 
ATOM   82    C CG  . ASP A 1 16  ? 163.067 152.121 110.005 1.00 38.79  ? 17  ASP A CG  1 
ATOM   83    O OD1 . ASP A 1 16  ? 162.678 153.188 109.493 1.00 35.50  ? 17  ASP A OD1 1 
ATOM   84    O OD2 . ASP A 1 16  ? 162.748 151.000 109.558 1.00 43.41  ? 17  ASP A OD2 1 
ATOM   85    N N   . GLY A 1 17  ? 165.466 154.812 109.627 1.00 25.21  ? 18  GLY A N   1 
ATOM   86    C CA  . GLY A 1 17  ? 165.638 156.247 109.491 1.00 23.69  ? 18  GLY A CA  1 
ATOM   87    C C   . GLY A 1 17  ? 164.466 157.076 109.974 1.00 27.03  ? 18  GLY A C   1 
ATOM   88    O O   . GLY A 1 17  ? 164.640 158.267 110.250 1.00 27.14  ? 18  GLY A O   1 
ATOM   89    N N   . ASP A 1 18  ? 163.282 156.481 110.081 1.00 28.44  ? 19  ASP A N   1 
ATOM   90    C CA  . ASP A 1 18  ? 162.091 157.208 110.501 1.00 25.88  ? 19  ASP A CA  1 
ATOM   91    C C   . ASP A 1 18  ? 161.832 157.128 111.999 1.00 25.41  ? 19  ASP A C   1 
ATOM   92    O O   . ASP A 1 18  ? 160.838 157.690 112.466 1.00 24.97  ? 19  ASP A O   1 
ATOM   93    C CB  . ASP A 1 18  ? 160.861 156.693 109.748 1.00 29.07  ? 19  ASP A CB  1 
ATOM   94    C CG  . ASP A 1 18  ? 161.170 156.313 108.315 1.00 43.67  ? 19  ASP A CG  1 
ATOM   95    O OD1 . ASP A 1 18  ? 161.320 157.224 107.475 1.00 50.98  ? 19  ASP A OD1 1 
ATOM   96    O OD2 . ASP A 1 18  ? 161.250 155.102 108.026 1.00 46.83  ? 19  ASP A OD2 1 
ATOM   97    N N   . ILE A 1 19  ? 162.694 156.453 112.762 1.00 25.52  ? 20  ILE A N   1 
ATOM   98    C CA  . ILE A 1 19  ? 162.457 156.311 114.196 1.00 20.45  ? 20  ILE A CA  1 
ATOM   99    C C   . ILE A 1 19  ? 162.569 157.653 114.910 1.00 22.21  ? 20  ILE A C   1 
ATOM   100   O O   . ILE A 1 19  ? 161.946 157.858 115.958 1.00 23.19  ? 20  ILE A O   1 
ATOM   101   C CB  . ILE A 1 19  ? 163.414 155.262 114.798 1.00 20.72  ? 20  ILE A CB  1 
ATOM   102   C CG1 . ILE A 1 19  ? 162.874 154.747 116.133 1.00 21.02  ? 20  ILE A CG1 1 
ATOM   103   C CG2 . ILE A 1 19  ? 164.817 155.829 114.971 1.00 17.61  ? 20  ILE A CG2 1 
ATOM   104   C CD1 . ILE A 1 19  ? 161.809 153.690 115.991 1.00 23.66  ? 20  ILE A CD1 1 
ATOM   105   N N   . GLY A 1 20  ? 163.350 158.585 114.368 1.00 20.10  ? 21  GLY A N   1 
ATOM   106   C CA  . GLY A 1 20  ? 163.538 159.872 115.001 1.00 17.13  ? 21  GLY A CA  1 
ATOM   107   C C   . GLY A 1 20  ? 162.471 160.901 114.725 1.00 21.62  ? 21  GLY A C   1 
ATOM   108   O O   . GLY A 1 20  ? 162.532 162.004 115.274 1.00 23.40  ? 21  GLY A O   1 
ATOM   109   N N   . ASN A 1 21  ? 161.489 160.576 113.887 1.00 22.62  ? 22  ASN A N   1 
ATOM   110   C CA  . ASN A 1 21  ? 160.430 161.503 113.515 1.00 20.58  ? 22  ASN A CA  1 
ATOM   111   C C   . ASN A 1 21  ? 159.149 161.280 114.305 1.00 22.49  ? 22  ASN A C   1 
ATOM   112   O O   . ASN A 1 21  ? 158.123 161.886 113.985 1.00 26.52  ? 22  ASN A O   1 
ATOM   113   C CB  . ASN A 1 21  ? 160.145 161.403 112.018 1.00 23.28  ? 22  ASN A CB  1 
ATOM   114   C CG  . ASN A 1 21  ? 161.357 161.725 111.175 1.00 23.63  ? 22  ASN A CG  1 
ATOM   115   O OD1 . ASN A 1 21  ? 162.264 162.425 111.617 1.00 21.56  ? 22  ASN A OD1 1 
ATOM   116   N ND2 . ASN A 1 21  ? 161.379 161.216 109.951 1.00 24.84  ? 22  ASN A ND2 1 
ATOM   117   N N   . TYR A 1 22  ? 159.180 160.423 115.320 1.00 20.80  ? 23  TYR A N   1 
ATOM   118   C CA  . TYR A 1 22  ? 158.035 160.218 116.194 1.00 18.44  ? 23  TYR A CA  1 
ATOM   119   C C   . TYR A 1 22  ? 158.172 161.119 117.411 1.00 20.33  ? 23  TYR A C   1 
ATOM   120   O O   . TYR A 1 22  ? 159.229 161.156 118.047 1.00 23.63  ? 23  TYR A O   1 
ATOM   121   C CB  . TYR A 1 22  ? 157.928 158.754 116.618 1.00 18.39  ? 23  TYR A CB  1 
ATOM   122   C CG  . TYR A 1 22  ? 157.726 157.808 115.459 1.00 23.61  ? 23  TYR A CG  1 
ATOM   123   C CD1 . TYR A 1 22  ? 156.493 157.701 114.833 1.00 28.77  ? 23  TYR A CD1 1 
ATOM   124   C CD2 . TYR A 1 22  ? 158.767 157.028 114.986 1.00 24.37  ? 23  TYR A CD2 1 
ATOM   125   C CE1 . TYR A 1 22  ? 156.306 156.843 113.770 1.00 27.84  ? 23  TYR A CE1 1 
ATOM   126   C CE2 . TYR A 1 22  ? 158.588 156.165 113.926 1.00 24.84  ? 23  TYR A CE2 1 
ATOM   127   C CZ  . TYR A 1 22  ? 157.357 156.078 113.322 1.00 27.82  ? 23  TYR A CZ  1 
ATOM   128   O OH  . TYR A 1 22  ? 157.178 155.219 112.264 1.00 28.56  ? 23  TYR A OH  1 
ATOM   129   N N   . TYR A 1 23  ? 157.110 161.855 117.722 1.00 19.47  ? 24  TYR A N   1 
ATOM   130   C CA  . TYR A 1 23  ? 157.114 162.827 118.807 1.00 17.53  ? 24  TYR A CA  1 
ATOM   131   C C   . TYR A 1 23  ? 156.139 162.366 119.878 1.00 17.85  ? 24  TYR A C   1 
ATOM   132   O O   . TYR A 1 23  ? 154.948 162.198 119.602 1.00 22.19  ? 24  TYR A O   1 
ATOM   133   C CB  . TYR A 1 23  ? 156.741 164.218 118.291 1.00 21.02  ? 24  TYR A CB  1 
ATOM   134   C CG  . TYR A 1 23  ? 157.279 165.357 119.124 1.00 25.07  ? 24  TYR A CG  1 
ATOM   135   C CD1 . TYR A 1 23  ? 158.643 165.523 119.309 1.00 26.23  ? 24  TYR A CD1 1 
ATOM   136   C CD2 . TYR A 1 23  ? 156.423 166.271 119.719 1.00 23.80  ? 24  TYR A CD2 1 
ATOM   137   C CE1 . TYR A 1 23  ? 159.139 166.560 120.068 1.00 24.33  ? 24  TYR A CE1 1 
ATOM   138   C CE2 . TYR A 1 23  ? 156.911 167.312 120.479 1.00 27.24  ? 24  TYR A CE2 1 
ATOM   139   C CZ  . TYR A 1 23  ? 158.269 167.451 120.650 1.00 27.76  ? 24  TYR A CZ  1 
ATOM   140   O OH  . TYR A 1 23  ? 158.760 168.488 121.406 1.00 37.71  ? 24  TYR A OH  1 
ATOM   141   N N   . TYR A 1 24  ? 156.644 162.160 121.094 1.00 17.05  ? 25  TYR A N   1 
ATOM   142   C CA  . TYR A 1 24  ? 155.772 161.774 122.198 1.00 18.28  ? 25  TYR A CA  1 
ATOM   143   C C   . TYR A 1 24  ? 154.817 162.901 122.565 1.00 21.59  ? 25  TYR A C   1 
ATOM   144   O O   . TYR A 1 24  ? 153.654 162.653 122.903 1.00 22.86  ? 25  TYR A O   1 
ATOM   145   C CB  . TYR A 1 24  ? 156.606 161.364 123.410 1.00 16.39  ? 25  TYR A CB  1 
ATOM   146   C CG  . TYR A 1 24  ? 156.921 159.889 123.475 1.00 15.68  ? 25  TYR A CG  1 
ATOM   147   C CD1 . TYR A 1 24  ? 157.648 159.269 122.470 1.00 15.30  ? 25  TYR A CD1 1 
ATOM   148   C CD2 . TYR A 1 24  ? 156.491 159.118 124.542 1.00 13.94  ? 25  TYR A CD2 1 
ATOM   149   C CE1 . TYR A 1 24  ? 157.937 157.926 122.528 1.00 13.37  ? 25  TYR A CE1 1 
ATOM   150   C CE2 . TYR A 1 24  ? 156.776 157.775 124.609 1.00 14.25  ? 25  TYR A CE2 1 
ATOM   151   C CZ  . TYR A 1 24  ? 157.498 157.182 123.601 1.00 14.60  ? 25  TYR A CZ  1 
ATOM   152   O OH  . TYR A 1 24  ? 157.782 155.839 123.667 1.00 15.98  ? 25  TYR A OH  1 
ATOM   153   N N   . GLY A 1 25  ? 155.287 164.133 122.513 1.00 21.06  ? 26  GLY A N   1 
ATOM   154   C CA  . GLY A 1 25  ? 154.469 165.281 122.851 1.00 21.84  ? 26  GLY A CA  1 
ATOM   155   C C   . GLY A 1 25  ? 155.322 166.399 123.405 1.00 27.59  ? 26  GLY A C   1 
ATOM   156   O O   . GLY A 1 25  ? 156.516 166.249 123.647 1.00 30.20  ? 26  GLY A O   1 
ATOM   157   N N   . GLN A 1 26  ? 154.677 167.544 123.606 1.00 32.09  ? 27  GLN A N   1 
ATOM   158   C CA  . GLN A 1 26  ? 155.373 168.706 124.139 1.00 35.25  ? 27  GLN A CA  1 
ATOM   159   C C   . GLN A 1 26  ? 155.630 168.526 125.629 1.00 37.18  ? 27  GLN A C   1 
ATOM   160   O O   . GLN A 1 26  ? 154.715 168.208 126.395 1.00 38.21  ? 27  GLN A O   1 
ATOM   161   C CB  . GLN A 1 26  ? 154.560 169.973 123.892 1.00 42.30  ? 27  GLN A CB  1 
ATOM   162   C CG  . GLN A 1 26  ? 155.263 171.245 124.320 1.00 48.27  ? 27  GLN A CG  1 
ATOM   163   C CD  . GLN A 1 26  ? 154.386 172.471 124.183 1.00 60.69  ? 27  GLN A CD  1 
ATOM   164   O OE1 . GLN A 1 26  ? 153.164 172.366 124.085 1.00 64.16  ? 27  GLN A OE1 1 
ATOM   165   N NE2 . GLN A 1 26  ? 155.007 173.644 124.171 1.00 63.13  ? 27  GLN A NE2 1 
ATOM   166   N N   . GLY A 1 27  ? 156.878 168.724 126.038 1.00 38.01  ? 28  GLY A N   1 
ATOM   167   C CA  . GLY A 1 27  ? 157.241 168.595 127.431 1.00 33.46  ? 28  GLY A CA  1 
ATOM   168   C C   . GLY A 1 27  ? 157.363 167.178 127.938 1.00 28.34  ? 28  GLY A C   1 
ATOM   169   O O   . GLY A 1 27  ? 157.556 166.986 129.142 1.00 28.62  ? 28  GLY A O   1 
ATOM   170   N N   . HIS A 1 28  ? 157.250 166.184 127.069 1.00 27.36  ? 29  HIS A N   1 
ATOM   171   C CA  . HIS A 1 28  ? 157.498 164.805 127.466 1.00 19.57  ? 29  HIS A CA  1 
ATOM   172   C C   . HIS A 1 28  ? 158.998 164.537 127.470 1.00 19.98  ? 29  HIS A C   1 
ATOM   173   O O   . HIS A 1 28  ? 159.677 164.848 126.487 1.00 21.75  ? 29  HIS A O   1 
ATOM   174   C CB  . HIS A 1 28  ? 156.793 163.833 126.528 1.00 17.58  ? 29  HIS A CB  1 
ATOM   175   C CG  . HIS A 1 28  ? 156.566 162.480 127.125 1.00 18.17  ? 29  HIS A CG  1 
ATOM   176   N ND1 . HIS A 1 28  ? 157.504 161.473 127.066 1.00 19.17  ? 29  HIS A ND1 1 
ATOM   177   C CD2 . HIS A 1 28  ? 155.512 161.971 127.803 1.00 23.14  ? 29  HIS A CD2 1 
ATOM   178   C CE1 . HIS A 1 28  ? 157.037 160.402 127.679 1.00 18.18  ? 29  HIS A CE1 1 
ATOM   179   N NE2 . HIS A 1 28  ? 155.829 160.677 128.136 1.00 21.12  ? 29  HIS A NE2 1 
ATOM   180   N N   . PRO A 1 29  ? 159.549 163.972 128.547 1.00 17.11  ? 30  PRO A N   1 
ATOM   181   C CA  . PRO A 1 29  ? 161.007 163.788 128.615 1.00 15.08  ? 30  PRO A CA  1 
ATOM   182   C C   . PRO A 1 29  ? 161.562 162.801 127.602 1.00 14.33  ? 30  PRO A C   1 
ATOM   183   O O   . PRO A 1 29  ? 162.779 162.790 127.387 1.00 15.98  ? 30  PRO A O   1 
ATOM   184   C CB  . PRO A 1 29  ? 161.231 163.295 130.051 1.00 13.30  ? 30  PRO A CB  1 
ATOM   185   C CG  . PRO A 1 29  ? 159.923 162.744 130.475 1.00 13.08  ? 30  PRO A CG  1 
ATOM   186   C CD  . PRO A 1 29  ? 158.879 163.553 129.788 1.00 15.03  ? 30  PRO A CD  1 
ATOM   187   N N   . MET A 1 30  ? 160.726 161.980 126.974 1.00 14.49  ? 31  MET A N   1 
ATOM   188   C CA  . MET A 1 30  ? 161.197 160.923 126.088 1.00 13.63  ? 31  MET A CA  1 
ATOM   189   C C   . MET A 1 30  ? 161.301 161.445 124.659 1.00 16.21  ? 31  MET A C   1 
ATOM   190   O O   . MET A 1 30  ? 160.291 161.819 124.053 1.00 16.59  ? 31  MET A O   1 
ATOM   191   C CB  . MET A 1 30  ? 160.264 159.718 126.165 1.00 11.96  ? 31  MET A CB  1 
ATOM   192   C CG  . MET A 1 30  ? 160.360 158.780 124.986 1.00 15.41  ? 31  MET A CG  1 
ATOM   193   S SD  . MET A 1 30  ? 161.461 157.385 125.253 1.00 20.46  ? 31  MET A SD  1 
ATOM   194   C CE  . MET A 1 30  ? 161.903 157.013 123.561 1.00 13.78  ? 31  MET A CE  1 
ATOM   195   N N   . LYS A 1 31  ? 162.519 161.464 124.127 1.00 16.16  ? 32  LYS A N   1 
ATOM   196   C CA  . LYS A 1 31  ? 162.796 161.982 122.786 1.00 14.37  ? 32  LYS A CA  1 
ATOM   197   C C   . LYS A 1 31  ? 163.337 160.876 121.893 1.00 13.25  ? 32  LYS A C   1 
ATOM   198   O O   . LYS A 1 31  ? 164.512 160.494 122.038 1.00 13.24  ? 32  LYS A O   1 
ATOM   199   C CB  . LYS A 1 31  ? 163.800 163.135 122.846 1.00 12.87  ? 32  LYS A CB  1 
ATOM   200   C CG  . LYS A 1 31  ? 163.486 164.208 123.872 1.00 12.65  ? 32  LYS A CG  1 
ATOM   201   C CD  . LYS A 1 31  ? 162.224 164.955 123.507 1.00 15.53  ? 32  LYS A CD  1 
ATOM   202   C CE  . LYS A 1 31  ? 161.913 166.048 124.506 1.00 20.86  ? 32  LYS A CE  1 
ATOM   203   N NZ  . LYS A 1 31  ? 160.456 166.335 124.544 1.00 22.77  ? 32  LYS A NZ  1 
ATOM   204   N N   . PRO A 1 32  ? 162.555 160.341 120.953 1.00 15.62  ? 33  PRO A N   1 
ATOM   205   C CA  . PRO A 1 32  ? 163.102 159.344 120.020 1.00 12.22  ? 33  PRO A CA  1 
ATOM   206   C C   . PRO A 1 32  ? 164.175 159.901 119.094 1.00 13.00  ? 33  PRO A C   1 
ATOM   207   O O   . PRO A 1 32  ? 164.718 159.174 118.259 1.00 12.63  ? 33  PRO A O   1 
ATOM   208   C CB  . PRO A 1 32  ? 161.866 158.892 119.231 1.00 12.99  ? 33  PRO A CB  1 
ATOM   209   C CG  . PRO A 1 32  ? 160.713 159.208 120.119 1.00 13.96  ? 33  PRO A CG  1 
ATOM   210   C CD  . PRO A 1 32  ? 161.095 160.469 120.825 1.00 15.07  ? 33  PRO A CD  1 
ATOM   211   N N   . HIS A 1 33  ? 164.485 161.191 119.229 1.00 15.79  ? 34  HIS A N   1 
ATOM   212   C CA  . HIS A 1 33  ? 165.522 161.842 118.439 1.00 13.90  ? 34  HIS A CA  1 
ATOM   213   C C   . HIS A 1 33  ? 166.927 161.532 118.936 1.00 15.78  ? 34  HIS A C   1 
ATOM   214   O O   . HIS A 1 33  ? 167.894 161.801 118.218 1.00 18.82  ? 34  HIS A O   1 
ATOM   215   C CB  . HIS A 1 33  ? 165.291 163.357 118.439 1.00 15.85  ? 34  HIS A CB  1 
ATOM   216   C CG  . HIS A 1 33  ? 166.289 164.130 117.633 1.00 19.52  ? 34  HIS A CG  1 
ATOM   217   N ND1 . HIS A 1 33  ? 166.472 163.929 116.283 1.00 21.04  ? 34  HIS A ND1 1 
ATOM   218   C CD2 . HIS A 1 33  ? 167.150 165.113 117.987 1.00 17.31  ? 34  HIS A CD2 1 
ATOM   219   C CE1 . HIS A 1 33  ? 167.406 164.750 115.841 1.00 20.22  ? 34  HIS A CE1 1 
ATOM   220   N NE2 . HIS A 1 33  ? 167.834 165.480 116.854 1.00 16.74  ? 34  HIS A NE2 1 
ATOM   221   N N   . ARG A 1 34  ? 167.069 160.963 120.134 1.00 14.37  ? 35  ARG A N   1 
ATOM   222   C CA  . ARG A 1 34  ? 168.388 160.617 120.646 1.00 11.21  ? 35  ARG A CA  1 
ATOM   223   C C   . ARG A 1 34  ? 169.022 159.451 119.903 1.00 12.37  ? 35  ARG A C   1 
ATOM   224   O O   . ARG A 1 34  ? 170.205 159.173 120.120 1.00 14.17  ? 35  ARG A O   1 
ATOM   225   C CB  . ARG A 1 34  ? 168.310 160.297 122.138 1.00 11.13  ? 35  ARG A CB  1 
ATOM   226   C CG  . ARG A 1 34  ? 167.625 158.989 122.476 1.00 8.48   ? 35  ARG A CG  1 
ATOM   227   C CD  . ARG A 1 34  ? 166.723 159.159 123.676 1.00 11.05  ? 35  ARG A CD  1 
ATOM   228   N NE  . ARG A 1 34  ? 166.676 157.975 124.524 1.00 13.01  ? 35  ARG A NE  1 
ATOM   229   C CZ  . ARG A 1 34  ? 165.904 156.924 124.296 1.00 11.80  ? 35  ARG A CZ  1 
ATOM   230   N NH1 . ARG A 1 34  ? 165.131 156.856 123.226 1.00 15.44  ? 35  ARG A NH1 1 
ATOM   231   N NH2 . ARG A 1 34  ? 165.910 155.914 125.160 1.00 8.51   ? 35  ARG A NH2 1 
ATOM   232   N N   . ILE A 1 35  ? 168.270 158.761 119.049 1.00 12.54  ? 36  ILE A N   1 
ATOM   233   C CA  . ILE A 1 35  ? 168.840 157.693 118.239 1.00 11.17  ? 36  ILE A CA  1 
ATOM   234   C C   . ILE A 1 35  ? 169.355 158.218 116.901 1.00 10.84  ? 36  ILE A C   1 
ATOM   235   O O   . ILE A 1 35  ? 170.324 157.679 116.358 1.00 12.04  ? 36  ILE A O   1 
ATOM   236   C CB  . ILE A 1 35  ? 167.806 156.573 118.039 1.00 12.42  ? 36  ILE A CB  1 
ATOM   237   C CG1 . ILE A 1 35  ? 167.116 156.244 119.364 1.00 11.07  ? 36  ILE A CG1 1 
ATOM   238   C CG2 . ILE A 1 35  ? 168.469 155.330 117.481 1.00 14.33  ? 36  ILE A CG2 1 
ATOM   239   C CD1 . ILE A 1 35  ? 165.687 155.795 119.214 1.00 10.85  ? 36  ILE A CD1 1 
ATOM   240   N N   . ARG A 1 36  ? 168.732 159.266 116.359 1.00 12.19  ? 37  ARG A N   1 
ATOM   241   C CA  . ARG A 1 36  ? 169.237 159.883 115.137 1.00 13.13  ? 37  ARG A CA  1 
ATOM   242   C C   . ARG A 1 36  ? 170.602 160.522 115.361 1.00 14.80  ? 37  ARG A C   1 
ATOM   243   O O   . ARG A 1 36  ? 171.507 160.381 114.528 1.00 18.96  ? 37  ARG A O   1 
ATOM   244   C CB  . ARG A 1 36  ? 168.234 160.917 114.629 1.00 14.60  ? 37  ARG A CB  1 
ATOM   245   C CG  . ARG A 1 36  ? 168.622 161.569 113.320 1.00 18.42  ? 37  ARG A CG  1 
ATOM   246   C CD  . ARG A 1 36  ? 167.396 162.025 112.553 1.00 21.47  ? 37  ARG A CD  1 
ATOM   247   N NE  . ARG A 1 36  ? 166.496 162.815 113.382 1.00 22.17  ? 37  ARG A NE  1 
ATOM   248   C CZ  . ARG A 1 36  ? 165.259 163.145 113.037 1.00 24.05  ? 37  ARG A CZ  1 
ATOM   249   N NH1 . ARG A 1 36  ? 164.741 162.769 111.881 1.00 24.68  ? 37  ARG A NH1 1 
ATOM   250   N NH2 . ARG A 1 36  ? 164.523 163.869 113.875 1.00 21.71  ? 37  ARG A NH2 1 
ATOM   251   N N   . MET A 1 37  ? 170.774 161.225 116.482 1.00 12.96  ? 38  MET A N   1 
ATOM   252   C CA  . MET A 1 37  ? 172.067 161.831 116.781 1.00 14.33  ? 38  MET A CA  1 
ATOM   253   C C   . MET A 1 37  ? 173.117 160.774 117.098 1.00 14.35  ? 38  MET A C   1 
ATOM   254   O O   . MET A 1 37  ? 174.291 160.934 116.745 1.00 18.05  ? 38  MET A O   1 
ATOM   255   C CB  . MET A 1 37  ? 171.929 162.827 117.928 1.00 17.50  ? 38  MET A CB  1 
ATOM   256   C CG  . MET A 1 37  ? 170.662 163.655 117.861 1.00 19.73  ? 38  MET A CG  1 
ATOM   257   S SD  . MET A 1 37  ? 170.408 164.722 119.288 1.00 29.49  ? 38  MET A SD  1 
ATOM   258   C CE  . MET A 1 37  ? 172.046 164.772 120.000 1.00 21.42  ? 38  MET A CE  1 
ATOM   259   N N   . THR A 1 38  ? 172.716 159.686 117.758 1.00 12.58  ? 39  THR A N   1 
ATOM   260   C CA  . THR A 1 38  ? 173.629 158.566 117.960 1.00 10.39  ? 39  THR A CA  1 
ATOM   261   C C   . THR A 1 38  ? 174.084 157.985 116.629 1.00 13.23  ? 39  THR A C   1 
ATOM   262   O O   . THR A 1 38  ? 175.273 157.704 116.439 1.00 16.72  ? 39  THR A O   1 
ATOM   263   C CB  . THR A 1 38  ? 172.955 157.485 118.804 1.00 8.50   ? 39  THR A CB  1 
ATOM   264   O OG1 . THR A 1 38  ? 172.310 158.083 119.933 1.00 9.20   ? 39  THR A OG1 1 
ATOM   265   C CG2 . THR A 1 38  ? 173.974 156.476 119.282 1.00 8.32   ? 39  THR A CG2 1 
ATOM   266   N N   . HIS A 1 39  ? 173.149 157.802 115.694 1.00 13.97  ? 40  HIS A N   1 
ATOM   267   C CA  . HIS A 1 39  ? 173.496 157.269 114.383 1.00 13.42  ? 40  HIS A CA  1 
ATOM   268   C C   . HIS A 1 39  ? 174.440 158.203 113.641 1.00 18.66  ? 40  HIS A C   1 
ATOM   269   O O   . HIS A 1 39  ? 175.383 157.750 112.985 1.00 21.28  ? 40  HIS A O   1 
ATOM   270   C CB  . HIS A 1 39  ? 172.226 157.034 113.569 1.00 15.15  ? 40  HIS A CB  1 
ATOM   271   C CG  . HIS A 1 39  ? 172.463 156.372 112.248 1.00 18.92  ? 40  HIS A CG  1 
ATOM   272   N ND1 . HIS A 1 39  ? 172.254 157.012 111.047 1.00 20.54  ? 40  HIS A ND1 1 
ATOM   273   C CD2 . HIS A 1 39  ? 172.882 155.122 111.940 1.00 19.96  ? 40  HIS A CD2 1 
ATOM   274   C CE1 . HIS A 1 39  ? 172.535 156.187 110.056 1.00 22.71  ? 40  HIS A CE1 1 
ATOM   275   N NE2 . HIS A 1 39  ? 172.919 155.033 110.570 1.00 21.58  ? 40  HIS A NE2 1 
ATOM   276   N N   . ASN A 1 40  ? 174.198 159.512 113.725 1.00 19.84  ? 41  ASN A N   1 
ATOM   277   C CA  . ASN A 1 40  ? 175.076 160.465 113.052 1.00 20.16  ? 41  ASN A CA  1 
ATOM   278   C C   . ASN A 1 40  ? 176.472 160.470 113.665 1.00 21.09  ? 41  ASN A C   1 
ATOM   279   O O   . ASN A 1 40  ? 177.473 160.547 112.941 1.00 27.38  ? 41  ASN A O   1 
ATOM   280   C CB  . ASN A 1 40  ? 174.466 161.862 113.095 1.00 23.60  ? 41  ASN A CB  1 
ATOM   281   C CG  . ASN A 1 40  ? 173.818 162.245 111.787 1.00 36.55  ? 41  ASN A CG  1 
ATOM   282   O OD1 . ASN A 1 40  ? 174.404 162.963 110.979 1.00 43.75  ? 41  ASN A OD1 1 
ATOM   283   N ND2 . ASN A 1 40  ? 172.603 161.760 111.566 1.00 30.67  ? 41  ASN A ND2 1 
ATOM   284   N N   . LEU A 1 41  ? 176.561 160.400 114.994 1.00 17.08  ? 42  LEU A N   1 
ATOM   285   C CA  . LEU A 1 41  ? 177.865 160.332 115.643 1.00 14.43  ? 42  LEU A CA  1 
ATOM   286   C C   . LEU A 1 41  ? 178.604 159.057 115.258 1.00 18.62  ? 42  LEU A C   1 
ATOM   287   O O   . LEU A 1 41  ? 179.825 159.071 115.073 1.00 24.01  ? 42  LEU A O   1 
ATOM   288   C CB  . LEU A 1 41  ? 177.701 160.426 117.159 1.00 16.46  ? 42  LEU A CB  1 
ATOM   289   C CG  . LEU A 1 41  ? 177.899 161.804 117.792 1.00 17.06  ? 42  LEU A CG  1 
ATOM   290   C CD1 . LEU A 1 41  ? 177.978 161.688 119.299 1.00 13.98  ? 42  LEU A CD1 1 
ATOM   291   C CD2 . LEU A 1 41  ? 179.142 162.477 117.243 1.00 25.60  ? 42  LEU A CD2 1 
ATOM   292   N N   . LEU A 1 42  ? 177.882 157.939 115.147 1.00 19.16  ? 43  LEU A N   1 
ATOM   293   C CA  . LEU A 1 42  ? 178.503 156.700 114.688 1.00 18.52  ? 43  LEU A CA  1 
ATOM   294   C C   . LEU A 1 42  ? 178.983 156.821 113.247 1.00 20.19  ? 43  LEU A C   1 
ATOM   295   O O   . LEU A 1 42  ? 180.057 156.318 112.899 1.00 22.57  ? 43  LEU A O   1 
ATOM   296   C CB  . LEU A 1 42  ? 177.522 155.536 114.825 1.00 18.24  ? 43  LEU A CB  1 
ATOM   297   C CG  . LEU A 1 42  ? 177.183 155.089 116.246 1.00 16.84  ? 43  LEU A CG  1 
ATOM   298   C CD1 . LEU A 1 42  ? 175.992 154.155 116.244 1.00 16.20  ? 43  LEU A CD1 1 
ATOM   299   C CD2 . LEU A 1 42  ? 178.377 154.424 116.881 1.00 17.82  ? 43  LEU A CD2 1 
ATOM   300   N N   . LEU A 1 43  ? 178.191 157.469 112.392 1.00 22.30  ? 44  LEU A N   1 
ATOM   301   C CA  . LEU A 1 43  ? 178.578 157.646 110.996 1.00 22.29  ? 44  LEU A CA  1 
ATOM   302   C C   . LEU A 1 43  ? 179.845 158.481 110.876 1.00 26.47  ? 44  LEU A C   1 
ATOM   303   O O   . LEU A 1 43  ? 180.768 158.127 110.135 1.00 31.83  ? 44  LEU A O   1 
ATOM   304   C CB  . LEU A 1 43  ? 177.439 158.304 110.218 1.00 21.25  ? 44  LEU A CB  1 
ATOM   305   C CG  . LEU A 1 43  ? 176.531 157.416 109.374 1.00 25.02  ? 44  LEU A CG  1 
ATOM   306   C CD1 . LEU A 1 43  ? 175.208 158.112 109.137 1.00 26.26  ? 44  LEU A CD1 1 
ATOM   307   C CD2 . LEU A 1 43  ? 177.201 157.080 108.058 1.00 34.52  ? 44  LEU A CD2 1 
ATOM   308   N N   . ASN A 1 44  ? 179.907 159.597 111.600 1.00 26.15  ? 45  ASN A N   1 
ATOM   309   C CA  . ASN A 1 44  ? 181.026 160.520 111.462 1.00 26.01  ? 45  ASN A CA  1 
ATOM   310   C C   . ASN A 1 44  ? 182.250 160.107 112.268 1.00 24.19  ? 45  ASN A C   1 
ATOM   311   O O   . ASN A 1 44  ? 183.332 160.656 112.037 1.00 26.95  ? 45  ASN A O   1 
ATOM   312   C CB  . ASN A 1 44  ? 180.584 161.926 111.861 1.00 27.09  ? 45  ASN A CB  1 
ATOM   313   C CG  . ASN A 1 44  ? 179.458 162.443 110.994 1.00 31.86  ? 45  ASN A CG  1 
ATOM   314   O OD1 . ASN A 1 44  ? 179.686 162.945 109.895 1.00 35.06  ? 45  ASN A OD1 1 
ATOM   315   N ND2 . ASN A 1 44  ? 178.231 162.308 111.476 1.00 30.88  ? 45  ASN A ND2 1 
ATOM   316   N N   . TYR A 1 45  ? 182.114 159.165 113.197 1.00 23.80  ? 46  TYR A N   1 
ATOM   317   C CA  . TYR A 1 45  ? 183.259 158.619 113.911 1.00 23.78  ? 46  TYR A CA  1 
ATOM   318   C C   . TYR A 1 45  ? 183.918 157.464 113.172 1.00 25.66  ? 46  TYR A C   1 
ATOM   319   O O   . TYR A 1 45  ? 184.976 156.996 113.605 1.00 30.81  ? 46  TYR A O   1 
ATOM   320   C CB  . TYR A 1 45  ? 182.844 158.150 115.307 1.00 22.01  ? 46  TYR A CB  1 
ATOM   321   C CG  . TYR A 1 45  ? 183.314 159.046 116.429 1.00 25.74  ? 46  TYR A CG  1 
ATOM   322   C CD1 . TYR A 1 45  ? 184.659 159.340 116.592 1.00 26.49  ? 46  TYR A CD1 1 
ATOM   323   C CD2 . TYR A 1 45  ? 182.411 159.592 117.330 1.00 24.48  ? 46  TYR A CD2 1 
ATOM   324   C CE1 . TYR A 1 45  ? 185.092 160.155 117.616 1.00 26.57  ? 46  TYR A CE1 1 
ATOM   325   C CE2 . TYR A 1 45  ? 182.835 160.407 118.358 1.00 27.76  ? 46  TYR A CE2 1 
ATOM   326   C CZ  . TYR A 1 45  ? 184.177 160.683 118.496 1.00 27.87  ? 46  TYR A CZ  1 
ATOM   327   O OH  . TYR A 1 45  ? 184.605 161.492 119.519 1.00 27.60  ? 46  TYR A OH  1 
ATOM   328   N N   . GLY A 1 46  ? 183.324 156.998 112.076 1.00 23.62  ? 47  GLY A N   1 
ATOM   329   C CA  . GLY A 1 46  ? 183.866 155.901 111.306 1.00 22.60  ? 47  GLY A CA  1 
ATOM   330   C C   . GLY A 1 46  ? 183.460 154.519 111.767 1.00 26.36  ? 47  GLY A C   1 
ATOM   331   O O   . GLY A 1 46  ? 183.925 153.532 111.184 1.00 31.02  ? 47  GLY A O   1 
ATOM   332   N N   . LEU A 1 47  ? 182.617 154.411 112.794 1.00 24.63  ? 48  LEU A N   1 
ATOM   333   C CA  . LEU A 1 47  ? 182.184 153.108 113.282 1.00 23.92  ? 48  LEU A CA  1 
ATOM   334   C C   . LEU A 1 47  ? 181.066 152.509 112.442 1.00 25.77  ? 48  LEU A C   1 
ATOM   335   O O   . LEU A 1 47  ? 180.812 151.306 112.544 1.00 29.50  ? 48  LEU A O   1 
ATOM   336   C CB  . LEU A 1 47  ? 181.730 153.216 114.738 1.00 22.94  ? 48  LEU A CB  1 
ATOM   337   C CG  . LEU A 1 47  ? 182.682 153.947 115.684 1.00 25.42  ? 48  LEU A CG  1 
ATOM   338   C CD1 . LEU A 1 47  ? 181.957 154.379 116.940 1.00 21.47  ? 48  LEU A CD1 1 
ATOM   339   C CD2 . LEU A 1 47  ? 183.880 153.078 116.025 1.00 25.11  ? 48  LEU A CD2 1 
ATOM   340   N N   . TYR A 1 48  ? 180.396 153.319 111.622 1.00 25.51  ? 49  TYR A N   1 
ATOM   341   C CA  . TYR A 1 48  ? 179.341 152.808 110.754 1.00 25.67  ? 49  TYR A CA  1 
ATOM   342   C C   . TYR A 1 48  ? 179.892 151.834 109.722 1.00 28.84  ? 49  TYR A C   1 
ATOM   343   O O   . TYR A 1 48  ? 179.249 150.824 109.418 1.00 33.03  ? 49  TYR A O   1 
ATOM   344   C CB  . TYR A 1 48  ? 178.634 153.981 110.072 1.00 25.76  ? 49  TYR A CB  1 
ATOM   345   C CG  . TYR A 1 48  ? 177.452 153.620 109.196 1.00 23.45  ? 49  TYR A CG  1 
ATOM   346   C CD1 . TYR A 1 48  ? 177.634 153.214 107.881 1.00 26.03  ? 49  TYR A CD1 1 
ATOM   347   C CD2 . TYR A 1 48  ? 176.156 153.715 109.676 1.00 19.99  ? 49  TYR A CD2 1 
ATOM   348   C CE1 . TYR A 1 48  ? 176.562 152.896 107.077 1.00 24.97  ? 49  TYR A CE1 1 
ATOM   349   C CE2 . TYR A 1 48  ? 175.078 153.399 108.876 1.00 22.32  ? 49  TYR A CE2 1 
ATOM   350   C CZ  . TYR A 1 48  ? 175.287 152.991 107.578 1.00 24.64  ? 49  TYR A CZ  1 
ATOM   351   O OH  . TYR A 1 48  ? 174.217 152.675 106.776 1.00 27.53  ? 49  TYR A OH  1 
ATOM   352   N N   . ARG A 1 49  ? 181.074 152.117 109.178 1.00 29.69  ? 50  ARG A N   1 
ATOM   353   C CA  . ARG A 1 49  ? 181.697 151.287 108.157 1.00 31.46  ? 50  ARG A CA  1 
ATOM   354   C C   . ARG A 1 49  ? 182.248 149.976 108.698 1.00 33.32  ? 50  ARG A C   1 
ATOM   355   O O   . ARG A 1 49  ? 182.636 149.115 107.903 1.00 35.61  ? 50  ARG A O   1 
ATOM   356   C CB  . ARG A 1 49  ? 182.828 152.066 107.484 1.00 40.23  ? 50  ARG A CB  1 
ATOM   357   C CG  . ARG A 1 49  ? 182.396 152.863 106.278 1.00 47.95  ? 50  ARG A CG  1 
ATOM   358   C CD  . ARG A 1 49  ? 183.399 153.948 105.945 1.00 65.59  ? 50  ARG A CD  1 
ATOM   359   N NE  . ARG A 1 49  ? 184.771 153.457 105.957 1.00 76.98  ? 50  ARG A NE  1 
ATOM   360   C CZ  . ARG A 1 49  ? 185.842 154.236 105.900 1.00 83.82  ? 50  ARG A CZ  1 
ATOM   361   N NH1 . ARG A 1 49  ? 185.737 155.554 105.850 1.00 80.87  ? 50  ARG A NH1 1 
ATOM   362   N NH2 . ARG A 1 49  ? 187.049 153.679 105.892 1.00 89.44  ? 50  ARG A NH2 1 
ATOM   363   N N   . LYS A 1 50  ? 182.300 149.806 110.015 1.00 31.37  ? 51  LYS A N   1 
ATOM   364   C CA  . LYS A 1 50  ? 182.952 148.660 110.629 1.00 28.82  ? 51  LYS A CA  1 
ATOM   365   C C   . LYS A 1 50  ? 181.995 147.528 110.976 1.00 30.41  ? 51  LYS A C   1 
ATOM   366   O O   . LYS A 1 50  ? 182.449 146.476 111.434 1.00 30.51  ? 51  LYS A O   1 
ATOM   367   C CB  . LYS A 1 50  ? 183.698 149.100 111.891 1.00 25.73  ? 51  LYS A CB  1 
ATOM   368   C CG  . LYS A 1 50  ? 184.985 149.850 111.623 1.00 24.68  ? 51  LYS A CG  1 
ATOM   369   C CD  . LYS A 1 50  ? 185.877 149.849 112.850 1.00 33.55  ? 51  LYS A CD  1 
ATOM   370   C CE  . LYS A 1 50  ? 187.270 150.353 112.522 1.00 39.63  ? 51  LYS A CE  1 
ATOM   371   N NZ  . LYS A 1 50  ? 188.224 150.094 113.635 1.00 38.13  ? 51  LYS A NZ  1 
ATOM   372   N N   . MET A 1 51  ? 180.692 147.706 110.770 1.00 26.23  ? 52  MET A N   1 
ATOM   373   C CA  . MET A 1 51  ? 179.721 146.686 111.135 1.00 24.82  ? 52  MET A CA  1 
ATOM   374   C C   . MET A 1 51  ? 178.745 146.470 109.989 1.00 28.09  ? 52  MET A C   1 
ATOM   375   O O   . MET A 1 51  ? 178.790 147.155 108.964 1.00 29.86  ? 52  MET A O   1 
ATOM   376   C CB  . MET A 1 51  ? 178.964 147.056 112.417 1.00 21.43  ? 52  MET A CB  1 
ATOM   377   C CG  . MET A 1 51  ? 178.919 148.536 112.720 1.00 21.41  ? 52  MET A CG  1 
ATOM   378   S SD  . MET A 1 51  ? 178.081 148.883 114.275 1.00 29.73  ? 52  MET A SD  1 
ATOM   379   C CE  . MET A 1 51  ? 178.074 150.673 114.260 1.00 20.94  ? 52  MET A CE  1 
ATOM   380   N N   . GLU A 1 52  ? 177.862 145.491 110.173 1.00 25.48  ? 53  GLU A N   1 
ATOM   381   C CA  . GLU A 1 52  ? 176.790 145.213 109.230 1.00 23.82  ? 53  GLU A CA  1 
ATOM   382   C C   . GLU A 1 52  ? 175.557 146.010 109.628 1.00 23.95  ? 53  GLU A C   1 
ATOM   383   O O   . GLU A 1 52  ? 175.137 145.973 110.788 1.00 23.87  ? 53  GLU A O   1 
ATOM   384   C CB  . GLU A 1 52  ? 176.463 143.721 109.200 1.00 25.67  ? 53  GLU A CB  1 
ATOM   385   C CG  . GLU A 1 52  ? 177.549 142.853 108.601 1.00 33.91  ? 53  GLU A CG  1 
ATOM   386   C CD  . GLU A 1 52  ? 176.988 141.631 107.906 1.00 41.20  ? 53  GLU A CD  1 
ATOM   387   O OE1 . GLU A 1 52  ? 175.821 141.280 108.173 1.00 39.54  ? 53  GLU A OE1 1 
ATOM   388   O OE2 . GLU A 1 52  ? 177.712 141.022 107.090 1.00 44.26  ? 53  GLU A OE2 1 
ATOM   389   N N   . ILE A 1 53  ? 174.980 146.725 108.668 1.00 27.24  ? 54  ILE A N   1 
ATOM   390   C CA  . ILE A 1 53  ? 173.869 147.634 108.917 1.00 23.42  ? 54  ILE A CA  1 
ATOM   391   C C   . ILE A 1 53  ? 172.605 147.022 108.337 1.00 25.25  ? 54  ILE A C   1 
ATOM   392   O O   . ILE A 1 53  ? 172.591 146.592 107.178 1.00 27.88  ? 54  ILE A O   1 
ATOM   393   C CB  . ILE A 1 53  ? 174.136 149.025 108.319 1.00 22.59  ? 54  ILE A CB  1 
ATOM   394   C CG1 . ILE A 1 53  ? 175.524 149.519 108.728 1.00 21.30  ? 54  ILE A CG1 1 
ATOM   395   C CG2 . ILE A 1 53  ? 173.072 150.009 108.769 1.00 24.51  ? 54  ILE A CG2 1 
ATOM   396   C CD1 . ILE A 1 53  ? 175.711 149.644 110.215 1.00 18.86  ? 54  ILE A CD1 1 
ATOM   397   N N   . TYR A 1 54  ? 171.546 146.983 109.142 1.00 25.18  ? 55  TYR A N   1 
ATOM   398   C CA  . TYR A 1 54  ? 170.280 146.392 108.745 1.00 24.65  ? 55  TYR A CA  1 
ATOM   399   C C   . TYR A 1 54  ? 169.151 147.393 108.928 1.00 25.13  ? 55  TYR A C   1 
ATOM   400   O O   . TYR A 1 54  ? 169.181 148.234 109.829 1.00 22.96  ? 55  TYR A O   1 
ATOM   401   C CB  . TYR A 1 54  ? 169.968 145.128 109.552 1.00 22.55  ? 55  TYR A CB  1 
ATOM   402   C CG  . TYR A 1 54  ? 170.804 143.934 109.174 1.00 25.15  ? 55  TYR A CG  1 
ATOM   403   C CD1 . TYR A 1 54  ? 170.409 143.086 108.154 1.00 27.97  ? 55  TYR A CD1 1 
ATOM   404   C CD2 . TYR A 1 54  ? 171.985 143.651 109.840 1.00 24.43  ? 55  TYR A CD2 1 
ATOM   405   C CE1 . TYR A 1 54  ? 171.166 141.995 107.804 1.00 26.76  ? 55  TYR A CE1 1 
ATOM   406   C CE2 . TYR A 1 54  ? 172.750 142.561 109.496 1.00 25.84  ? 55  TYR A CE2 1 
ATOM   407   C CZ  . TYR A 1 54  ? 172.336 141.737 108.477 1.00 25.58  ? 55  TYR A CZ  1 
ATOM   408   O OH  . TYR A 1 54  ? 173.094 140.646 108.127 1.00 32.05  ? 55  TYR A OH  1 
ATOM   409   N N   . ARG A 1 55  ? 168.153 147.289 108.056 1.00 29.18  ? 56  ARG A N   1 
ATOM   410   C CA  . ARG A 1 55  ? 166.920 148.045 108.190 1.00 29.74  ? 56  ARG A CA  1 
ATOM   411   C C   . ARG A 1 55  ? 165.886 147.131 108.826 1.00 30.86  ? 56  ARG A C   1 
ATOM   412   O O   . ARG A 1 55  ? 165.439 146.177 108.174 1.00 35.13  ? 56  ARG A O   1 
ATOM   413   C CB  . ARG A 1 55  ? 166.440 148.531 106.825 1.00 37.00  ? 56  ARG A CB  1 
ATOM   414   C CG  . ARG A 1 55  ? 166.049 149.996 106.754 1.00 38.12  ? 56  ARG A CG  1 
ATOM   415   C CD  . ARG A 1 55  ? 164.986 150.209 105.688 1.00 44.46  ? 56  ARG A CD  1 
ATOM   416   N NE  . ARG A 1 55  ? 164.756 151.620 105.402 1.00 56.08  ? 56  ARG A NE  1 
ATOM   417   C CZ  . ARG A 1 55  ? 163.874 152.383 106.033 1.00 52.99  ? 56  ARG A CZ  1 
ATOM   418   N NH1 . ARG A 1 55  ? 163.094 151.897 106.983 1.00 47.48  ? 56  ARG A NH1 1 
ATOM   419   N NH2 . ARG A 1 55  ? 163.766 153.665 105.694 1.00 44.98  ? 56  ARG A NH2 1 
ATOM   420   N N   . PRO A 1 56  ? 165.483 147.364 110.072 1.00 27.83  ? 57  PRO A N   1 
ATOM   421   C CA  . PRO A 1 56  ? 164.618 146.399 110.753 1.00 27.66  ? 57  PRO A CA  1 
ATOM   422   C C   . PRO A 1 56  ? 163.253 146.302 110.095 1.00 35.63  ? 57  PRO A C   1 
ATOM   423   O O   . PRO A 1 56  ? 162.732 147.268 109.534 1.00 44.73  ? 57  PRO A O   1 
ATOM   424   C CB  . PRO A 1 56  ? 164.512 146.964 112.172 1.00 23.26  ? 57  PRO A CB  1 
ATOM   425   C CG  . PRO A 1 56  ? 164.698 148.418 111.996 1.00 22.94  ? 57  PRO A CG  1 
ATOM   426   C CD  . PRO A 1 56  ? 165.693 148.575 110.881 1.00 27.36  ? 57  PRO A CD  1 
ATOM   427   N N   . HIS A 1 57  ? 162.678 145.108 110.161 1.00 31.44  ? 58  HIS A N   1 
ATOM   428   C CA  . HIS A 1 57  ? 161.324 144.912 109.681 1.00 31.27  ? 58  HIS A CA  1 
ATOM   429   C C   . HIS A 1 57  ? 160.322 145.422 110.710 1.00 31.62  ? 58  HIS A C   1 
ATOM   430   O O   . HIS A 1 57  ? 160.626 145.564 111.897 1.00 30.80  ? 58  HIS A O   1 
ATOM   431   C CB  . HIS A 1 57  ? 161.065 143.436 109.377 1.00 36.36  ? 58  HIS A CB  1 
ATOM   432   C CG  . HIS A 1 57  ? 160.939 142.578 110.598 1.00 37.29  ? 58  HIS A CG  1 
ATOM   433   N ND1 . HIS A 1 57  ? 161.734 142.744 111.711 1.00 37.53  ? 58  HIS A ND1 1 
ATOM   434   C CD2 . HIS A 1 57  ? 160.102 141.553 110.884 1.00 38.81  ? 58  HIS A CD2 1 
ATOM   435   C CE1 . HIS A 1 57  ? 161.397 141.854 112.627 1.00 35.28  ? 58  HIS A CE1 1 
ATOM   436   N NE2 . HIS A 1 57  ? 160.408 141.120 112.151 1.00 39.98  ? 58  HIS A NE2 1 
ATOM   437   N N   . LYS A 1 58  ? 159.114 145.707 110.238 1.00 31.38  ? 59  LYS A N   1 
ATOM   438   C CA  . LYS A 1 58  ? 158.029 146.115 111.122 1.00 28.60  ? 59  LYS A CA  1 
ATOM   439   C C   . LYS A 1 58  ? 157.398 144.863 111.716 1.00 30.80  ? 59  LYS A C   1 
ATOM   440   O O   . LYS A 1 58  ? 156.796 144.062 110.994 1.00 33.80  ? 59  LYS A O   1 
ATOM   441   C CB  . LYS A 1 58  ? 157.005 146.951 110.364 1.00 30.43  ? 59  LYS A CB  1 
ATOM   442   C CG  . LYS A 1 58  ? 157.537 148.292 109.893 1.00 33.01  ? 59  LYS A CG  1 
ATOM   443   C CD  . LYS A 1 58  ? 157.070 149.418 110.794 1.00 32.92  ? 59  LYS A CD  1 
ATOM   444   C CE  . LYS A 1 58  ? 156.440 150.541 109.990 1.00 36.67  ? 59  LYS A CE  1 
ATOM   445   N NZ  . LYS A 1 58  ? 157.293 150.950 108.841 1.00 33.56  ? 59  LYS A NZ  1 
ATOM   446   N N   . ALA A 1 59  ? 157.546 144.687 113.026 1.00 28.14  ? 60  ALA A N   1 
ATOM   447   C CA  . ALA A 1 59  ? 157.019 143.504 113.690 1.00 30.80  ? 60  ALA A CA  1 
ATOM   448   C C   . ALA A 1 59  ? 155.502 143.467 113.577 1.00 38.30  ? 60  ALA A C   1 
ATOM   449   O O   . ALA A 1 59  ? 154.816 144.403 113.997 1.00 37.90  ? 60  ALA A O   1 
ATOM   450   C CB  . ALA A 1 59  ? 157.446 143.492 115.155 1.00 26.16  ? 60  ALA A CB  1 
ATOM   451   N N   . THR A 1 60  ? 154.980 142.383 113.013 1.00 41.37  ? 61  THR A N   1 
ATOM   452   C CA  . THR A 1 60  ? 153.543 142.249 112.854 1.00 38.68  ? 61  THR A CA  1 
ATOM   453   C C   . THR A 1 60  ? 152.867 142.112 114.215 1.00 39.89  ? 61  THR A C   1 
ATOM   454   O O   . THR A 1 60  ? 153.493 141.766 115.219 1.00 38.19  ? 61  THR A O   1 
ATOM   455   C CB  . THR A 1 60  ? 153.207 141.042 111.979 1.00 43.44  ? 61  THR A CB  1 
ATOM   456   O OG1 . THR A 1 60  ? 153.795 139.864 112.541 1.00 41.68  ? 61  THR A OG1 1 
ATOM   457   C CG2 . THR A 1 60  ? 153.737 141.242 110.571 1.00 46.84  ? 61  THR A CG2 1 
ATOM   458   N N   . ALA A 1 61  ? 151.565 142.404 114.238 1.00 41.85  ? 62  ALA A N   1 
ATOM   459   C CA  . ALA A 1 61  ? 150.808 142.299 115.479 1.00 35.49  ? 62  ALA A CA  1 
ATOM   460   C C   . ALA A 1 61  ? 150.766 140.867 115.993 1.00 35.19  ? 62  ALA A C   1 
ATOM   461   O O   . ALA A 1 61  ? 150.610 140.647 117.198 1.00 33.45  ? 62  ALA A O   1 
ATOM   462   C CB  . ALA A 1 61  ? 149.392 142.834 115.277 1.00 36.75  ? 62  ALA A CB  1 
ATOM   463   N N   . GLU A 1 62  ? 150.902 139.882 115.103 1.00 38.62  ? 63  GLU A N   1 
ATOM   464   C CA  . GLU A 1 62  ? 150.919 138.490 115.539 1.00 36.91  ? 63  GLU A CA  1 
ATOM   465   C C   . GLU A 1 62  ? 152.200 138.151 116.290 1.00 39.60  ? 63  GLU A C   1 
ATOM   466   O O   . GLU A 1 62  ? 152.184 137.301 117.187 1.00 40.25  ? 63  GLU A O   1 
ATOM   467   C CB  . GLU A 1 62  ? 150.744 137.561 114.339 1.00 37.58  ? 63  GLU A CB  1 
ATOM   468   C CG  . GLU A 1 62  ? 149.704 138.036 113.340 1.00 45.77  ? 63  GLU A CG  1 
ATOM   469   C CD  . GLU A 1 62  ? 150.316 138.760 112.158 1.00 50.10  ? 63  GLU A CD  1 
ATOM   470   O OE1 . GLU A 1 62  ? 151.337 138.275 111.627 1.00 49.92  ? 63  GLU A OE1 1 
ATOM   471   O OE2 . GLU A 1 62  ? 149.777 139.815 111.761 1.00 52.48  ? 63  GLU A OE2 1 
ATOM   472   N N   . GLU A 1 63  ? 153.317 138.789 115.932 1.00 40.62  ? 64  GLU A N   1 
ATOM   473   C CA  . GLU A 1 63  ? 154.553 138.593 116.680 1.00 36.94  ? 64  GLU A CA  1 
ATOM   474   C C   . GLU A 1 63  ? 154.469 139.208 118.070 1.00 35.37  ? 64  GLU A C   1 
ATOM   475   O O   . GLU A 1 63  ? 155.051 138.673 119.019 1.00 37.20  ? 64  GLU A O   1 
ATOM   476   C CB  . GLU A 1 63  ? 155.734 139.185 115.914 1.00 37.08  ? 64  GLU A CB  1 
ATOM   477   C CG  . GLU A 1 63  ? 155.960 138.578 114.541 1.00 44.93  ? 64  GLU A CG  1 
ATOM   478   C CD  . GLU A 1 63  ? 157.308 138.952 113.954 1.00 53.51  ? 64  GLU A CD  1 
ATOM   479   O OE1 . GLU A 1 63  ? 158.167 139.453 114.709 1.00 50.24  ? 64  GLU A OE1 1 
ATOM   480   O OE2 . GLU A 1 63  ? 157.508 138.747 112.738 1.00 54.79  ? 64  GLU A OE2 1 
ATOM   481   N N   . MET A 1 64  ? 153.761 140.331 118.208 1.00 32.79  ? 65  MET A N   1 
ATOM   482   C CA  . MET A 1 64  ? 153.645 140.982 119.508 1.00 26.87  ? 65  MET A CA  1 
ATOM   483   C C   . MET A 1 64  ? 152.802 140.166 120.479 1.00 28.37  ? 65  MET A C   1 
ATOM   484   O O   . MET A 1 64  ? 153.073 140.172 121.683 1.00 30.99  ? 65  MET A O   1 
ATOM   485   C CB  . MET A 1 64  ? 153.052 142.379 119.343 1.00 25.82  ? 65  MET A CB  1 
ATOM   486   C CG  . MET A 1 64  ? 153.856 143.290 118.440 1.00 27.82  ? 65  MET A CG  1 
ATOM   487   S SD  . MET A 1 64  ? 153.219 144.971 118.422 1.00 41.73  ? 65  MET A SD  1 
ATOM   488   C CE  . MET A 1 64  ? 154.544 145.819 117.580 1.00 26.06  ? 65  MET A CE  1 
ATOM   489   N N   . THR A 1 65  ? 151.784 139.465 119.984 1.00 30.56  ? 66  THR A N   1 
ATOM   490   C CA  . THR A 1 65  ? 150.889 138.693 120.838 1.00 31.59  ? 66  THR A CA  1 
ATOM   491   C C   . THR A 1 65  ? 151.486 137.367 121.290 1.00 34.45  ? 66  THR A C   1 
ATOM   492   O O   . THR A 1 65  ? 150.768 136.562 121.891 1.00 37.12  ? 66  THR A O   1 
ATOM   493   C CB  . THR A 1 65  ? 149.557 138.437 120.129 1.00 32.65  ? 66  THR A CB  1 
ATOM   494   O OG1 . THR A 1 65  ? 149.770 137.587 118.996 1.00 37.49  ? 66  THR A OG1 1 
ATOM   495   C CG2 . THR A 1 65  ? 148.928 139.742 119.682 1.00 32.58  ? 66  THR A CG2 1 
ATOM   496   N N   . LYS A 1 66  ? 152.766 137.114 121.012 1.00 32.86  ? 67  LYS A N   1 
ATOM   497   C CA  . LYS A 1 66  ? 153.434 135.980 121.640 1.00 29.65  ? 67  LYS A CA  1 
ATOM   498   C C   . LYS A 1 66  ? 153.572 136.190 123.141 1.00 29.66  ? 67  LYS A C   1 
ATOM   499   O O   . LYS A 1 66  ? 153.606 135.218 123.903 1.00 31.38  ? 67  LYS A O   1 
ATOM   500   C CB  . LYS A 1 66  ? 154.804 135.752 121.004 1.00 29.46  ? 67  LYS A CB  1 
ATOM   501   C CG  . LYS A 1 66  ? 154.759 135.460 119.517 1.00 32.61  ? 67  LYS A CG  1 
ATOM   502   C CD  . LYS A 1 66  ? 155.276 134.068 119.211 1.00 36.62  ? 67  LYS A CD  1 
ATOM   503   C CE  . LYS A 1 66  ? 156.255 134.086 118.048 1.00 43.65  ? 67  LYS A CE  1 
ATOM   504   N NZ  . LYS A 1 66  ? 155.574 134.315 116.745 1.00 41.71  ? 67  LYS A NZ  1 
ATOM   505   N N   . TYR A 1 67  ? 153.659 137.446 123.578 1.00 28.65  ? 68  TYR A N   1 
ATOM   506   C CA  . TYR A 1 67  ? 153.646 137.808 124.988 1.00 27.48  ? 68  TYR A CA  1 
ATOM   507   C C   . TYR A 1 67  ? 152.415 138.614 125.371 1.00 28.99  ? 68  TYR A C   1 
ATOM   508   O O   . TYR A 1 67  ? 151.683 138.230 126.286 1.00 31.62  ? 68  TYR A O   1 
ATOM   509   C CB  . TYR A 1 67  ? 154.913 138.600 125.343 1.00 24.82  ? 68  TYR A CB  1 
ATOM   510   C CG  . TYR A 1 67  ? 154.901 139.201 126.732 1.00 25.38  ? 68  TYR A CG  1 
ATOM   511   C CD1 . TYR A 1 67  ? 154.567 138.436 127.840 1.00 26.64  ? 68  TYR A CD1 1 
ATOM   512   C CD2 . TYR A 1 67  ? 155.235 140.532 126.936 1.00 22.09  ? 68  TYR A CD2 1 
ATOM   513   C CE1 . TYR A 1 67  ? 154.560 138.979 129.106 1.00 24.89  ? 68  TYR A CE1 1 
ATOM   514   C CE2 . TYR A 1 67  ? 155.230 141.083 128.200 1.00 21.37  ? 68  TYR A CE2 1 
ATOM   515   C CZ  . TYR A 1 67  ? 154.891 140.301 129.280 1.00 25.58  ? 68  TYR A CZ  1 
ATOM   516   O OH  . TYR A 1 67  ? 154.885 140.844 130.543 1.00 31.14  ? 68  TYR A OH  1 
ATOM   517   N N   . HIS A 1 68  ? 152.163 139.724 124.685 1.00 29.90  ? 69  HIS A N   1 
ATOM   518   C CA  . HIS A 1 68  ? 151.063 140.599 125.050 1.00 28.42  ? 69  HIS A CA  1 
ATOM   519   C C   . HIS A 1 68  ? 149.724 139.971 124.678 1.00 33.51  ? 69  HIS A C   1 
ATOM   520   O O   . HIS A 1 68  ? 149.637 139.075 123.835 1.00 36.17  ? 69  HIS A O   1 
ATOM   521   C CB  . HIS A 1 68  ? 151.214 141.960 124.372 1.00 26.50  ? 69  HIS A CB  1 
ATOM   522   C CG  . HIS A 1 68  ? 152.470 142.683 124.748 1.00 26.13  ? 69  HIS A CG  1 
ATOM   523   N ND1 . HIS A 1 68  ? 152.608 143.364 125.937 1.00 25.01  ? 69  HIS A ND1 1 
ATOM   524   C CD2 . HIS A 1 68  ? 153.646 142.824 124.095 1.00 22.18  ? 69  HIS A CD2 1 
ATOM   525   C CE1 . HIS A 1 68  ? 153.815 143.895 126.000 1.00 18.99  ? 69  HIS A CE1 1 
ATOM   526   N NE2 . HIS A 1 68  ? 154.464 143.583 124.894 1.00 20.68  ? 69  HIS A NE2 1 
ATOM   527   N N   . SER A 1 69  ? 148.670 140.447 125.334 1.00 35.47  ? 70  SER A N   1 
ATOM   528   C CA  . SER A 1 69  ? 147.333 139.958 125.048 1.00 35.32  ? 70  SER A CA  1 
ATOM   529   C C   . SER A 1 69  ? 146.845 140.495 123.706 1.00 36.08  ? 70  SER A C   1 
ATOM   530   O O   . SER A 1 69  ? 147.340 141.499 123.190 1.00 35.42  ? 70  SER A O   1 
ATOM   531   C CB  . SER A 1 69  ? 146.367 140.356 126.163 1.00 34.76  ? 70  SER A CB  1 
ATOM   532   O OG  . SER A 1 69  ? 146.267 141.763 126.270 1.00 35.96  ? 70  SER A OG  1 
ATOM   533   N N   . ASP A 1 70  ? 145.864 139.797 123.133 1.00 40.35  ? 71  ASP A N   1 
ATOM   534   C CA  . ASP A 1 70  ? 145.335 140.202 121.835 1.00 40.77  ? 71  ASP A CA  1 
ATOM   535   C C   . ASP A 1 70  ? 144.542 141.499 121.936 1.00 42.51  ? 71  ASP A C   1 
ATOM   536   O O   . ASP A 1 70  ? 144.594 142.335 121.027 1.00 41.65  ? 71  ASP A O   1 
ATOM   537   C CB  . ASP A 1 70  ? 144.469 139.088 121.251 1.00 45.71  ? 71  ASP A CB  1 
ATOM   538   C CG  . ASP A 1 70  ? 143.960 139.415 119.862 1.00 56.71  ? 71  ASP A CG  1 
ATOM   539   O OD1 . ASP A 1 70  ? 144.651 140.162 119.136 1.00 58.34  ? 71  ASP A OD1 1 
ATOM   540   O OD2 . ASP A 1 70  ? 142.870 138.928 119.496 1.00 62.00  ? 71  ASP A OD2 1 
ATOM   541   N N   . GLU A 1 71  ? 143.797 141.681 123.029 1.00 44.18  ? 72  GLU A N   1 
ATOM   542   C CA  . GLU A 1 71  ? 143.011 142.899 123.196 1.00 43.32  ? 72  GLU A CA  1 
ATOM   543   C C   . GLU A 1 71  ? 143.907 144.125 123.319 1.00 39.45  ? 72  GLU A C   1 
ATOM   544   O O   . GLU A 1 71  ? 143.603 145.184 122.757 1.00 37.42  ? 72  GLU A O   1 
ATOM   545   C CB  . GLU A 1 71  ? 142.106 142.772 124.419 1.00 43.36  ? 72  GLU A CB  1 
ATOM   546   C CG  . GLU A 1 71  ? 141.519 141.386 124.602 1.00 49.17  ? 72  GLU A CG  1 
ATOM   547   C CD  . GLU A 1 71  ? 142.231 140.592 125.676 1.00 55.81  ? 72  GLU A CD  1 
ATOM   548   O OE1 . GLU A 1 71  ? 142.834 141.214 126.576 1.00 53.22  ? 72  GLU A OE1 1 
ATOM   549   O OE2 . GLU A 1 71  ? 142.191 139.345 125.619 1.00 58.83  ? 72  GLU A OE2 1 
ATOM   550   N N   . TYR A 1 72  ? 145.014 144.002 124.054 1.00 37.70  ? 73  TYR A N   1 
ATOM   551   C CA  . TYR A 1 72  ? 145.929 145.126 124.222 1.00 31.42  ? 73  TYR A CA  1 
ATOM   552   C C   . TYR A 1 72  ? 146.562 145.528 122.897 1.00 30.40  ? 73  TYR A C   1 
ATOM   553   O O   . TYR A 1 72  ? 146.640 146.719 122.571 1.00 31.94  ? 73  TYR A O   1 
ATOM   554   C CB  . TYR A 1 72  ? 147.000 144.762 125.248 1.00 29.80  ? 73  TYR A CB  1 
ATOM   555   C CG  . TYR A 1 72  ? 148.073 145.804 125.433 1.00 28.48  ? 73  TYR A CG  1 
ATOM   556   C CD1 . TYR A 1 72  ? 147.754 147.097 125.819 1.00 28.74  ? 73  TYR A CD1 1 
ATOM   557   C CD2 . TYR A 1 72  ? 149.409 145.491 125.236 1.00 26.90  ? 73  TYR A CD2 1 
ATOM   558   C CE1 . TYR A 1 72  ? 148.734 148.048 125.994 1.00 27.08  ? 73  TYR A CE1 1 
ATOM   559   C CE2 . TYR A 1 72  ? 150.392 146.435 125.407 1.00 25.63  ? 73  TYR A CE2 1 
ATOM   560   C CZ  . TYR A 1 72  ? 150.050 147.710 125.787 1.00 26.23  ? 73  TYR A CZ  1 
ATOM   561   O OH  . TYR A 1 72  ? 151.032 148.653 125.960 1.00 30.08  ? 73  TYR A OH  1 
ATOM   562   N N   . ILE A 1 73  ? 147.006 144.547 122.110 1.00 29.24  ? 74  ILE A N   1 
ATOM   563   C CA  . ILE A 1 73  ? 147.619 144.847 120.821 1.00 30.22  ? 74  ILE A CA  1 
ATOM   564   C C   . ILE A 1 73  ? 146.583 145.402 119.852 1.00 36.28  ? 74  ILE A C   1 
ATOM   565   O O   . ILE A 1 73  ? 146.882 146.287 119.042 1.00 38.68  ? 74  ILE A O   1 
ATOM   566   C CB  . ILE A 1 73  ? 148.319 143.595 120.263 1.00 29.77  ? 74  ILE A CB  1 
ATOM   567   C CG1 . ILE A 1 73  ? 149.429 143.145 121.212 1.00 30.71  ? 74  ILE A CG1 1 
ATOM   568   C CG2 . ILE A 1 73  ? 148.888 143.866 118.884 1.00 28.67  ? 74  ILE A CG2 1 
ATOM   569   C CD1 . ILE A 1 73  ? 150.392 144.246 121.594 1.00 29.65  ? 74  ILE A CD1 1 
ATOM   570   N N   . LYS A 1 74  ? 145.347 144.901 119.921 1.00 37.24  ? 75  LYS A N   1 
ATOM   571   C CA  . LYS A 1 74  ? 144.283 145.436 119.078 1.00 36.11  ? 75  LYS A CA  1 
ATOM   572   C C   . LYS A 1 74  ? 143.979 146.889 119.426 1.00 35.56  ? 75  LYS A C   1 
ATOM   573   O O   . LYS A 1 74  ? 143.760 147.716 118.533 1.00 38.96  ? 75  LYS A O   1 
ATOM   574   C CB  . LYS A 1 74  ? 143.028 144.576 119.216 1.00 41.44  ? 75  LYS A CB  1 
ATOM   575   C CG  . LYS A 1 74  ? 142.233 144.429 117.932 1.00 47.44  ? 75  LYS A CG  1 
ATOM   576   C CD  . LYS A 1 74  ? 140.953 143.644 118.161 1.00 48.23  ? 75  LYS A CD  1 
ATOM   577   C CE  . LYS A 1 74  ? 140.186 144.180 119.356 1.00 47.09  ? 75  LYS A CE  1 
ATOM   578   N NZ  . LYS A 1 74  ? 139.543 145.489 119.059 1.00 45.03  ? 75  LYS A NZ  1 
ATOM   579   N N   . PHE A 1 75  ? 143.954 147.216 120.720 1.00 34.28  ? 76  PHE A N   1 
ATOM   580   C CA  . PHE A 1 75  ? 143.762 148.604 121.130 1.00 34.60  ? 76  PHE A CA  1 
ATOM   581   C C   . PHE A 1 75  ? 144.917 149.480 120.663 1.00 35.08  ? 76  PHE A C   1 
ATOM   582   O O   . PHE A 1 75  ? 144.704 150.612 120.213 1.00 36.22  ? 76  PHE A O   1 
ATOM   583   C CB  . PHE A 1 75  ? 143.606 148.690 122.647 1.00 35.18  ? 76  PHE A CB  1 
ATOM   584   C CG  . PHE A 1 75  ? 143.713 150.087 123.187 1.00 35.93  ? 76  PHE A CG  1 
ATOM   585   C CD1 . PHE A 1 75  ? 142.680 150.989 123.017 1.00 38.51  ? 76  PHE A CD1 1 
ATOM   586   C CD2 . PHE A 1 75  ? 144.848 150.499 123.863 1.00 35.70  ? 76  PHE A CD2 1 
ATOM   587   C CE1 . PHE A 1 75  ? 142.777 152.273 123.510 1.00 38.56  ? 76  PHE A CE1 1 
ATOM   588   C CE2 . PHE A 1 75  ? 144.948 151.782 124.358 1.00 35.57  ? 76  PHE A CE2 1 
ATOM   589   C CZ  . PHE A 1 75  ? 143.912 152.668 124.181 1.00 34.45  ? 76  PHE A CZ  1 
ATOM   590   N N   . LEU A 1 76  ? 146.149 148.976 120.767 1.00 32.66  ? 77  LEU A N   1 
ATOM   591   C CA  . LEU A 1 76  ? 147.301 149.732 120.284 1.00 30.72  ? 77  LEU A CA  1 
ATOM   592   C C   . LEU A 1 76  ? 147.198 149.991 118.787 1.00 32.30  ? 77  LEU A C   1 
ATOM   593   O O   . LEU A 1 76  ? 147.538 151.080 118.310 1.00 34.94  ? 77  LEU A O   1 
ATOM   594   C CB  . LEU A 1 76  ? 148.594 148.984 120.603 1.00 31.40  ? 77  LEU A CB  1 
ATOM   595   C CG  . LEU A 1 76  ? 149.137 149.042 122.031 1.00 29.13  ? 77  LEU A CG  1 
ATOM   596   C CD1 . LEU A 1 76  ? 150.359 148.154 122.150 1.00 25.40  ? 77  LEU A CD1 1 
ATOM   597   C CD2 . LEU A 1 76  ? 149.468 150.465 122.433 1.00 23.25  ? 77  LEU A CD2 1 
ATOM   598   N N   . ARG A 1 77  ? 146.744 148.993 118.029 1.00 34.96  ? 78  ARG A N   1 
ATOM   599   C CA  . ARG A 1 77  ? 146.600 149.147 116.587 1.00 34.25  ? 78  ARG A CA  1 
ATOM   600   C C   . ARG A 1 77  ? 145.455 150.081 116.222 1.00 37.31  ? 78  ARG A C   1 
ATOM   601   O O   . ARG A 1 77  ? 145.510 150.746 115.182 1.00 39.81  ? 78  ARG A O   1 
ATOM   602   C CB  . ARG A 1 77  ? 146.388 147.779 115.941 1.00 31.76  ? 78  ARG A CB  1 
ATOM   603   C CG  . ARG A 1 77  ? 146.894 147.673 114.518 1.00 37.49  ? 78  ARG A CG  1 
ATOM   604   C CD  . ARG A 1 77  ? 146.987 146.223 114.083 1.00 41.19  ? 78  ARG A CD  1 
ATOM   605   N NE  . ARG A 1 77  ? 146.015 145.388 114.777 1.00 49.77  ? 78  ARG A NE  1 
ATOM   606   C CZ  . ARG A 1 77  ? 145.644 144.180 114.375 1.00 58.29  ? 78  ARG A CZ  1 
ATOM   607   N NH1 . ARG A 1 77  ? 146.148 143.630 113.282 1.00 55.53  ? 78  ARG A NH1 1 
ATOM   608   N NH2 . ARG A 1 77  ? 144.747 143.506 115.089 1.00 57.38  ? 78  ARG A NH2 1 
ATOM   609   N N   . SER A 1 78  ? 144.416 150.147 117.054 1.00 38.53  ? 79  SER A N   1 
ATOM   610   C CA  . SER A 1 78  ? 143.211 150.888 116.705 1.00 38.51  ? 79  SER A CA  1 
ATOM   611   C C   . SER A 1 78  ? 143.237 152.344 117.149 1.00 43.98  ? 79  SER A C   1 
ATOM   612   O O   . SER A 1 78  ? 142.632 153.192 116.483 1.00 50.25  ? 79  SER A O   1 
ATOM   613   C CB  . SER A 1 78  ? 141.985 150.202 117.310 1.00 42.49  ? 79  SER A CB  1 
ATOM   614   O OG  . SER A 1 78  ? 142.051 148.798 117.133 1.00 44.47  ? 79  SER A OG  1 
ATOM   615   N N   . ILE A 1 79  ? 143.918 152.661 118.251 1.00 42.45  ? 80  ILE A N   1 
ATOM   616   C CA  . ILE A 1 79  ? 143.845 154.003 118.815 1.00 42.34  ? 80  ILE A CA  1 
ATOM   617   C C   . ILE A 1 79  ? 144.627 154.987 117.952 1.00 45.72  ? 80  ILE A C   1 
ATOM   618   O O   . ILE A 1 79  ? 145.727 154.689 117.467 1.00 45.85  ? 80  ILE A O   1 
ATOM   619   C CB  . ILE A 1 79  ? 144.346 154.001 120.271 1.00 38.40  ? 80  ILE A CB  1 
ATOM   620   C CG1 . ILE A 1 79  ? 144.006 155.323 120.960 1.00 41.45  ? 80  ILE A CG1 1 
ATOM   621   C CG2 . ILE A 1 79  ? 145.841 153.720 120.348 1.00 38.50  ? 80  ILE A CG2 1 
ATOM   622   C CD1 . ILE A 1 79  ? 142.542 155.496 121.253 1.00 46.82  ? 80  ILE A CD1 1 
ATOM   623   N N   . ARG A 1 80  ? 144.040 156.155 117.727 1.00 47.39  ? 81  ARG A N   1 
ATOM   624   C CA  . ARG A 1 80  ? 144.690 157.286 117.085 1.00 50.55  ? 81  ARG A CA  1 
ATOM   625   C C   . ARG A 1 80  ? 144.320 158.541 117.857 1.00 52.61  ? 81  ARG A C   1 
ATOM   626   O O   . ARG A 1 80  ? 143.334 158.548 118.602 1.00 56.50  ? 81  ARG A O   1 
ATOM   627   C CB  . ARG A 1 80  ? 144.287 157.438 115.609 1.00 54.71  ? 81  ARG A CB  1 
ATOM   628   C CG  . ARG A 1 80  ? 144.510 156.202 114.755 1.00 59.55  ? 81  ARG A CG  1 
ATOM   629   C CD  . ARG A 1 80  ? 144.028 156.408 113.324 1.00 63.75  ? 81  ARG A CD  1 
ATOM   630   N NE  . ARG A 1 80  ? 142.848 157.257 113.228 1.00 67.59  ? 81  ARG A NE  1 
ATOM   631   C CZ  . ARG A 1 80  ? 141.598 156.815 113.275 1.00 70.75  ? 81  ARG A CZ  1 
ATOM   632   N NH1 . ARG A 1 80  ? 141.324 155.529 113.417 1.00 66.61  ? 81  ARG A NH1 1 
ATOM   633   N NH2 . ARG A 1 80  ? 140.598 157.686 113.177 1.00 72.27  ? 81  ARG A NH2 1 
ATOM   634   N N   . PRO A 1 81  ? 145.102 159.618 117.720 1.00 52.23  ? 82  PRO A N   1 
ATOM   635   C CA  . PRO A 1 81  ? 144.732 160.875 118.392 1.00 53.62  ? 82  PRO A CA  1 
ATOM   636   C C   . PRO A 1 81  ? 143.398 161.441 117.936 1.00 58.38  ? 82  PRO A C   1 
ATOM   637   O O   . PRO A 1 81  ? 142.784 162.215 118.680 1.00 54.61  ? 82  PRO A O   1 
ATOM   638   C CB  . PRO A 1 81  ? 145.888 161.821 118.037 1.00 48.39  ? 82  PRO A CB  1 
ATOM   639   C CG  . PRO A 1 81  ? 147.013 160.937 117.669 1.00 42.60  ? 82  PRO A CG  1 
ATOM   640   C CD  . PRO A 1 81  ? 146.407 159.721 117.046 1.00 48.75  ? 82  PRO A CD  1 
ATOM   641   N N   . ASP A 1 82  ? 142.933 161.084 116.738 1.00 62.87  ? 83  ASP A N   1 
ATOM   642   C CA  . ASP A 1 82  ? 141.682 161.627 116.223 1.00 60.46  ? 83  ASP A CA  1 
ATOM   643   C C   . ASP A 1 82  ? 140.459 160.994 116.873 1.00 64.02  ? 83  ASP A C   1 
ATOM   644   O O   . ASP A 1 82  ? 139.419 161.651 116.988 1.00 69.92  ? 83  ASP A O   1 
ATOM   645   C CB  . ASP A 1 82  ? 141.617 161.438 114.707 1.00 63.07  ? 83  ASP A CB  1 
ATOM   646   C CG  . ASP A 1 82  ? 142.949 161.689 114.033 1.00 71.11  ? 83  ASP A CG  1 
ATOM   647   O OD1 . ASP A 1 82  ? 143.634 162.663 114.408 1.00 71.00  ? 83  ASP A OD1 1 
ATOM   648   O OD2 . ASP A 1 82  ? 143.315 160.910 113.128 1.00 79.99  ? 83  ASP A OD2 1 
ATOM   649   N N   . ASN A 1 83  ? 140.553 159.736 117.297 1.00 61.10  ? 84  ASN A N   1 
ATOM   650   C CA  . ASN A 1 83  ? 139.416 158.992 117.823 1.00 59.52  ? 84  ASN A CA  1 
ATOM   651   C C   . ASN A 1 83  ? 139.620 158.621 119.287 1.00 60.92  ? 84  ASN A C   1 
ATOM   652   O O   . ASN A 1 83  ? 139.260 157.527 119.726 1.00 63.40  ? 84  ASN A O   1 
ATOM   653   C CB  . ASN A 1 83  ? 139.153 157.743 116.986 1.00 62.99  ? 84  ASN A CB  1 
ATOM   654   C CG  . ASN A 1 83  ? 140.297 156.755 117.041 1.00 60.26  ? 84  ASN A CG  1 
ATOM   655   O OD1 . ASN A 1 83  ? 141.172 156.754 116.182 1.00 60.19  ? 84  ASN A OD1 1 
ATOM   656   N ND2 . ASN A 1 83  ? 140.292 155.902 118.055 1.00 57.57  ? 84  ASN A ND2 1 
ATOM   657   N N   . MET A 1 84  ? 140.197 159.534 120.065 1.00 61.27  ? 85  MET A N   1 
ATOM   658   C CA  . MET A 1 84  ? 140.420 159.288 121.483 1.00 60.66  ? 85  MET A CA  1 
ATOM   659   C C   . MET A 1 84  ? 139.140 159.345 122.306 1.00 61.94  ? 85  MET A C   1 
ATOM   660   O O   . MET A 1 84  ? 139.166 158.978 123.485 1.00 61.77  ? 85  MET A O   1 
ATOM   661   C CB  . MET A 1 84  ? 141.428 160.298 122.034 1.00 59.53  ? 85  MET A CB  1 
ATOM   662   C CG  . MET A 1 84  ? 142.825 159.742 122.230 1.00 53.38  ? 85  MET A CG  1 
ATOM   663   S SD  . MET A 1 84  ? 144.017 161.032 122.636 1.00 64.07  ? 85  MET A SD  1 
ATOM   664   C CE  . MET A 1 84  ? 143.645 161.308 124.364 1.00 52.05  ? 85  MET A CE  1 
ATOM   665   N N   . SER A 1 85  ? 138.029 159.795 121.719 1.00 61.24  ? 86  SER A N   1 
ATOM   666   C CA  . SER A 1 85  ? 136.786 159.943 122.470 1.00 62.78  ? 86  SER A CA  1 
ATOM   667   C C   . SER A 1 85  ? 136.112 158.603 122.739 1.00 63.26  ? 86  SER A C   1 
ATOM   668   O O   . SER A 1 85  ? 135.563 158.390 123.825 1.00 63.43  ? 86  SER A O   1 
ATOM   669   C CB  . SER A 1 85  ? 135.833 160.870 121.717 1.00 62.63  ? 86  SER A CB  1 
ATOM   670   O OG  . SER A 1 85  ? 135.394 160.270 120.511 1.00 66.46  ? 86  SER A OG  1 
ATOM   671   N N   . GLU A 1 86  ? 136.135 157.692 121.767 1.00 62.39  ? 87  GLU A N   1 
ATOM   672   C CA  . GLU A 1 86  ? 135.408 156.435 121.882 1.00 63.81  ? 87  GLU A CA  1 
ATOM   673   C C   . GLU A 1 86  ? 136.123 155.396 122.734 1.00 63.25  ? 87  GLU A C   1 
ATOM   674   O O   . GLU A 1 86  ? 135.506 154.388 123.094 1.00 66.02  ? 87  GLU A O   1 
ATOM   675   C CB  . GLU A 1 86  ? 135.149 155.849 120.493 1.00 65.13  ? 87  GLU A CB  1 
ATOM   676   C CG  . GLU A 1 86  ? 134.816 156.881 119.433 1.00 68.85  ? 87  GLU A CG  1 
ATOM   677   C CD  . GLU A 1 86  ? 135.358 156.506 118.070 1.00 74.08  ? 87  GLU A CD  1 
ATOM   678   O OE1 . GLU A 1 86  ? 135.214 155.330 117.675 1.00 77.47  ? 87  GLU A OE1 1 
ATOM   679   O OE2 . GLU A 1 86  ? 135.924 157.388 117.391 1.00 75.34  ? 87  GLU A OE2 1 
ATOM   680   N N   . TYR A 1 87  ? 137.395 155.607 123.065 1.00 60.32  ? 88  TYR A N   1 
ATOM   681   C CA  . TYR A 1 87  ? 138.200 154.595 123.736 1.00 56.65  ? 88  TYR A CA  1 
ATOM   682   C C   . TYR A 1 87  ? 138.548 154.959 125.173 1.00 54.64  ? 88  TYR A C   1 
ATOM   683   O O   . TYR A 1 87  ? 139.450 154.342 125.746 1.00 56.59  ? 88  TYR A O   1 
ATOM   684   C CB  . TYR A 1 87  ? 139.486 154.340 122.947 1.00 53.75  ? 88  TYR A CB  1 
ATOM   685   C CG  . TYR A 1 87  ? 139.285 153.573 121.663 1.00 56.36  ? 88  TYR A CG  1 
ATOM   686   C CD1 . TYR A 1 87  ? 138.925 154.224 120.493 1.00 58.06  ? 88  TYR A CD1 1 
ATOM   687   C CD2 . TYR A 1 87  ? 139.466 152.198 121.617 1.00 54.88  ? 88  TYR A CD2 1 
ATOM   688   C CE1 . TYR A 1 87  ? 138.742 153.528 119.316 1.00 57.72  ? 88  TYR A CE1 1 
ATOM   689   C CE2 . TYR A 1 87  ? 139.288 151.494 120.444 1.00 56.85  ? 88  TYR A CE2 1 
ATOM   690   C CZ  . TYR A 1 87  ? 138.925 152.165 119.296 1.00 58.83  ? 88  TYR A CZ  1 
ATOM   691   O OH  . TYR A 1 87  ? 138.744 151.472 118.122 1.00 56.51  ? 88  TYR A OH  1 
ATOM   692   N N   . SER A 1 88  ? 137.842 155.917 125.779 1.00 51.47  ? 89  SER A N   1 
ATOM   693   C CA  . SER A 1 88  ? 138.255 156.435 127.082 1.00 51.30  ? 89  SER A CA  1 
ATOM   694   C C   . SER A 1 88  ? 138.327 155.330 128.131 1.00 49.50  ? 89  SER A C   1 
ATOM   695   O O   . SER A 1 88  ? 139.273 155.280 128.927 1.00 50.33  ? 89  SER A O   1 
ATOM   696   C CB  . SER A 1 88  ? 137.301 157.540 127.531 1.00 54.41  ? 89  SER A CB  1 
ATOM   697   O OG  . SER A 1 88  ? 137.656 158.782 126.949 1.00 60.15  ? 89  SER A OG  1 
ATOM   698   N N   . LYS A 1 89  ? 137.341 154.432 128.145 1.00 48.81  ? 90  LYS A N   1 
ATOM   699   C CA  . LYS A 1 89  ? 137.399 153.293 129.054 1.00 47.58  ? 90  LYS A CA  1 
ATOM   700   C C   . LYS A 1 89  ? 138.568 152.377 128.713 1.00 49.61  ? 90  LYS A C   1 
ATOM   701   O O   . LYS A 1 89  ? 139.234 151.847 129.610 1.00 48.87  ? 90  LYS A O   1 
ATOM   702   C CB  . LYS A 1 89  ? 136.080 152.523 129.012 1.00 52.12  ? 90  LYS A CB  1 
ATOM   703   C CG  . LYS A 1 89  ? 134.976 153.143 129.851 1.00 55.50  ? 90  LYS A CG  1 
ATOM   704   C CD  . LYS A 1 89  ? 133.608 152.641 129.425 1.00 53.49  ? 90  LYS A CD  1 
ATOM   705   C CE  . LYS A 1 89  ? 132.921 153.629 128.497 1.00 53.12  ? 90  LYS A CE  1 
ATOM   706   N NZ  . LYS A 1 89  ? 133.642 153.785 127.203 1.00 51.52  ? 90  LYS A NZ  1 
ATOM   707   N N   . GLN A 1 90  ? 138.828 152.174 127.419 1.00 49.83  ? 91  GLN A N   1 
ATOM   708   C CA  . GLN A 1 90  ? 139.959 151.349 127.009 1.00 46.00  ? 91  GLN A CA  1 
ATOM   709   C C   . GLN A 1 90  ? 141.286 151.988 127.402 1.00 43.08  ? 91  GLN A C   1 
ATOM   710   O O   . GLN A 1 90  ? 142.202 151.293 127.855 1.00 42.06  ? 91  GLN A O   1 
ATOM   711   C CB  . GLN A 1 90  ? 139.904 151.099 125.504 1.00 47.77  ? 91  GLN A CB  1 
ATOM   712   C CG  . GLN A 1 90  ? 138.498 150.904 124.968 1.00 53.24  ? 91  GLN A CG  1 
ATOM   713   C CD  . GLN A 1 90  ? 138.367 149.659 124.118 1.00 62.50  ? 91  GLN A CD  1 
ATOM   714   O OE1 . GLN A 1 90  ? 139.147 148.717 124.253 1.00 61.33  ? 91  GLN A OE1 1 
ATOM   715   N NE2 . GLN A 1 90  ? 137.374 149.646 123.237 1.00 59.21  ? 91  GLN A NE2 1 
ATOM   716   N N   . MET A 1 91  ? 141.411 153.307 127.231 1.00 41.91  ? 92  MET A N   1 
ATOM   717   C CA  . MET A 1 91  ? 142.623 153.993 127.670 1.00 37.02  ? 92  MET A CA  1 
ATOM   718   C C   . MET A 1 91  ? 142.799 153.886 129.178 1.00 41.20  ? 92  MET A C   1 
ATOM   719   O O   . MET A 1 91  ? 143.921 153.720 129.668 1.00 41.48  ? 92  MET A O   1 
ATOM   720   C CB  . MET A 1 91  ? 142.596 155.459 127.237 1.00 35.18  ? 92  MET A CB  1 
ATOM   721   C CG  . MET A 1 91  ? 142.126 155.691 125.818 1.00 39.44  ? 92  MET A CG  1 
ATOM   722   S SD  . MET A 1 91  ? 142.854 157.149 125.059 1.00 50.12  ? 92  MET A SD  1 
ATOM   723   C CE  . MET A 1 91  ? 142.754 158.314 126.412 1.00 40.95  ? 92  MET A CE  1 
ATOM   724   N N   . GLN A 1 92  ? 141.703 153.990 129.931 1.00 45.43  ? 93  GLN A N   1 
ATOM   725   C CA  . GLN A 1 92  ? 141.788 153.827 131.379 1.00 45.32  ? 93  GLN A CA  1 
ATOM   726   C C   . GLN A 1 92  ? 142.229 152.417 131.752 1.00 41.98  ? 93  GLN A C   1 
ATOM   727   O O   . GLN A 1 92  ? 143.001 152.230 132.699 1.00 39.84  ? 93  GLN A O   1 
ATOM   728   C CB  . GLN A 1 92  ? 140.441 154.156 132.022 1.00 48.19  ? 93  GLN A CB  1 
ATOM   729   C CG  . GLN A 1 92  ? 140.416 155.477 132.772 1.00 53.56  ? 93  GLN A CG  1 
ATOM   730   C CD  . GLN A 1 92  ? 141.116 155.399 134.113 1.00 63.70  ? 93  GLN A CD  1 
ATOM   731   O OE1 . GLN A 1 92  ? 140.921 154.450 134.873 1.00 64.36  ? 93  GLN A OE1 1 
ATOM   732   N NE2 . GLN A 1 92  ? 141.937 156.399 134.412 1.00 64.61  ? 93  GLN A NE2 1 
ATOM   733   N N   . ARG A 1 93  ? 141.743 151.410 131.023 1.00 44.31  ? 94  ARG A N   1 
ATOM   734   C CA  . ARG A 1 93  ? 142.071 150.027 131.357 1.00 41.00  ? 94  ARG A CA  1 
ATOM   735   C C   . ARG A 1 93  ? 143.517 149.691 131.013 1.00 40.98  ? 94  ARG A C   1 
ATOM   736   O O   . ARG A 1 93  ? 144.199 149.005 131.782 1.00 40.01  ? 94  ARG A O   1 
ATOM   737   C CB  . ARG A 1 93  ? 141.120 149.074 130.636 1.00 39.80  ? 94  ARG A CB  1 
ATOM   738   C CG  . ARG A 1 93  ? 141.120 147.663 131.197 1.00 43.48  ? 94  ARG A CG  1 
ATOM   739   C CD  . ARG A 1 93  ? 141.081 146.626 130.090 1.00 47.48  ? 94  ARG A CD  1 
ATOM   740   N NE  . ARG A 1 93  ? 140.046 146.921 129.106 1.00 53.81  ? 94  ARG A NE  1 
ATOM   741   C CZ  . ARG A 1 93  ? 139.506 146.022 128.294 1.00 58.28  ? 94  ARG A CZ  1 
ATOM   742   N NH1 . ARG A 1 93  ? 139.875 144.752 128.324 1.00 52.58  ? 94  ARG A NH1 1 
ATOM   743   N NH2 . ARG A 1 93  ? 138.573 146.409 127.429 1.00 60.22  ? 94  ARG A NH2 1 
ATOM   744   N N   . PHE A 1 94  ? 144.001 150.161 129.865 1.00 42.46  ? 95  PHE A N   1 
ATOM   745   C CA  . PHE A 1 94  ? 145.312 149.786 129.354 1.00 36.78  ? 95  PHE A CA  1 
ATOM   746   C C   . PHE A 1 94  ? 146.412 150.766 129.741 1.00 34.60  ? 95  PHE A C   1 
ATOM   747   O O   . PHE A 1 94  ? 147.542 150.620 129.265 1.00 35.24  ? 95  PHE A O   1 
ATOM   748   C CB  . PHE A 1 94  ? 145.258 149.638 127.832 1.00 32.22  ? 95  PHE A CB  1 
ATOM   749   C CG  . PHE A 1 94  ? 144.397 148.501 127.365 1.00 34.48  ? 95  PHE A CG  1 
ATOM   750   C CD1 . PHE A 1 94  ? 144.584 147.225 127.864 1.00 35.24  ? 95  PHE A CD1 1 
ATOM   751   C CD2 . PHE A 1 94  ? 143.401 148.706 126.430 1.00 36.80  ? 95  PHE A CD2 1 
ATOM   752   C CE1 . PHE A 1 94  ? 143.793 146.179 127.437 1.00 35.97  ? 95  PHE A CE1 1 
ATOM   753   C CE2 . PHE A 1 94  ? 142.610 147.663 126.000 1.00 37.79  ? 95  PHE A CE2 1 
ATOM   754   C CZ  . PHE A 1 94  ? 142.806 146.399 126.504 1.00 35.83  ? 95  PHE A CZ  1 
ATOM   755   N N   . ASN A 1 95  ? 146.105 151.764 130.572 1.00 33.86  ? 96  ASN A N   1 
ATOM   756   C CA  . ASN A 1 95  ? 147.106 152.678 131.127 1.00 31.20  ? 96  ASN A CA  1 
ATOM   757   C C   . ASN A 1 95  ? 147.781 153.505 130.032 1.00 31.81  ? 96  ASN A C   1 
ATOM   758   O O   . ASN A 1 95  ? 148.992 153.727 130.044 1.00 34.21  ? 96  ASN A O   1 
ATOM   759   C CB  . ASN A 1 95  ? 148.141 151.910 131.955 1.00 32.11  ? 96  ASN A CB  1 
ATOM   760   C CG  . ASN A 1 95  ? 148.951 152.808 132.866 1.00 34.32  ? 96  ASN A CG  1 
ATOM   761   O OD1 . ASN A 1 95  ? 148.811 154.029 132.841 1.00 39.64  ? 96  ASN A OD1 1 
ATOM   762   N ND2 . ASN A 1 95  ? 149.814 152.204 133.671 1.00 32.26  ? 96  ASN A ND2 1 
ATOM   763   N N   . VAL A 1 96  ? 146.982 153.975 129.079 1.00 31.22  ? 97  VAL A N   1 
ATOM   764   C CA  . VAL A 1 96  ? 147.480 154.725 127.933 1.00 29.75  ? 97  VAL A CA  1 
ATOM   765   C C   . VAL A 1 96  ? 146.851 156.110 127.943 1.00 33.65  ? 97  VAL A C   1 
ATOM   766   O O   . VAL A 1 96  ? 145.623 156.239 127.961 1.00 37.36  ? 97  VAL A O   1 
ATOM   767   C CB  . VAL A 1 96  ? 147.179 153.997 126.609 1.00 28.65  ? 97  VAL A CB  1 
ATOM   768   C CG1 . VAL A 1 96  ? 147.298 154.950 125.440 1.00 29.63  ? 97  VAL A CG1 1 
ATOM   769   C CG2 . VAL A 1 96  ? 148.113 152.815 126.429 1.00 31.01  ? 97  VAL A CG2 1 
ATOM   770   N N   . GLY A 1 97  ? 147.691 157.143 127.933 1.00 35.68  ? 98  GLY A N   1 
ATOM   771   C CA  . GLY A 1 97  ? 147.207 158.498 127.756 1.00 34.96  ? 98  GLY A CA  1 
ATOM   772   C C   . GLY A 1 97  ? 147.802 159.562 128.659 1.00 38.98  ? 98  GLY A C   1 
ATOM   773   O O   . GLY A 1 97  ? 148.001 160.696 128.215 1.00 39.36  ? 98  GLY A O   1 
ATOM   774   N N   . GLU A 1 98  ? 148.093 159.232 129.917 1.00 40.34  ? 99  GLU A N   1 
ATOM   775   C CA  . GLU A 1 98  ? 148.621 160.232 130.855 1.00 45.93  ? 99  GLU A CA  1 
ATOM   776   C C   . GLU A 1 98  ? 150.133 160.384 130.705 1.00 41.04  ? 99  GLU A C   1 
ATOM   777   O O   . GLU A 1 98  ? 150.623 161.441 130.299 1.00 37.02  ? 99  GLU A O   1 
ATOM   778   C CB  . GLU A 1 98  ? 148.246 159.858 132.290 1.00 47.75  ? 99  GLU A CB  1 
ATOM   779   C CG  . GLU A 1 98  ? 146.753 159.863 132.569 1.00 53.78  ? 99  GLU A CG  1 
ATOM   780   C CD  . GLU A 1 98  ? 146.434 159.576 134.023 1.00 68.67  ? 99  GLU A CD  1 
ATOM   781   O OE1 . GLU A 1 98  ? 147.382 159.420 134.820 1.00 67.01  ? 99  GLU A OE1 1 
ATOM   782   O OE2 . GLU A 1 98  ? 145.236 159.506 134.370 1.00 71.46  ? 99  GLU A OE2 1 
ATOM   783   N N   . ASP A 1 99  ? 150.879 159.323 131.016 1.00 39.94  ? 100 ASP A N   1 
ATOM   784   C CA  . ASP A 1 99  ? 152.327 159.317 130.864 1.00 36.50  ? 100 ASP A CA  1 
ATOM   785   C C   . ASP A 1 99  ? 152.788 158.549 129.639 1.00 38.77  ? 100 ASP A C   1 
ATOM   786   O O   . ASP A 1 99  ? 153.907 158.778 129.170 1.00 35.31  ? 100 ASP A O   1 
ATOM   787   C CB  . ASP A 1 99  ? 152.997 158.718 132.108 1.00 36.66  ? 100 ASP A CB  1 
ATOM   788   C CG  . ASP A 1 99  ? 152.255 157.508 132.645 1.00 47.51  ? 100 ASP A CG  1 
ATOM   789   O OD1 . ASP A 1 99  ? 151.074 157.654 133.026 1.00 48.14  ? 100 ASP A OD1 1 
ATOM   790   O OD2 . ASP A 1 99  ? 152.850 156.410 132.686 1.00 46.05  ? 100 ASP A OD2 1 
ATOM   791   N N   . CYS A 1 100 ? 151.960 157.643 129.126 1.00 37.80  ? 101 CYS A N   1 
ATOM   792   C CA  . CYS A 1 100 ? 152.167 156.975 127.853 1.00 30.00  ? 101 CYS A CA  1 
ATOM   793   C C   . CYS A 1 100 ? 151.169 157.570 126.871 1.00 27.40  ? 101 CYS A C   1 
ATOM   794   O O   . CYS A 1 100 ? 150.082 157.014 126.673 1.00 28.58  ? 101 CYS A O   1 
ATOM   795   C CB  . CYS A 1 100 ? 151.980 155.465 127.992 1.00 26.93  ? 101 CYS A CB  1 
ATOM   796   S SG  . CYS A 1 100 ? 153.019 154.697 129.247 1.00 30.69  ? 101 CYS A SG  1 
ATOM   797   N N   . PRO A 1 101 ? 151.496 158.698 126.248 1.00 26.53  ? 102 PRO A N   1 
ATOM   798   C CA  . PRO A 1 101 ? 150.491 159.441 125.483 1.00 25.41  ? 102 PRO A CA  1 
ATOM   799   C C   . PRO A 1 101 ? 150.136 158.746 124.179 1.00 25.95  ? 102 PRO A C   1 
ATOM   800   O O   . PRO A 1 101 ? 150.808 157.827 123.712 1.00 26.16  ? 102 PRO A O   1 
ATOM   801   C CB  . PRO A 1 101 ? 151.175 160.785 125.228 1.00 24.86  ? 102 PRO A CB  1 
ATOM   802   C CG  . PRO A 1 101 ? 152.621 160.458 125.210 1.00 19.84  ? 102 PRO A CG  1 
ATOM   803   C CD  . PRO A 1 101 ? 152.817 159.346 126.200 1.00 21.59  ? 102 PRO A CD  1 
ATOM   804   N N   . VAL A 1 102 ? 149.038 159.207 123.594 1.00 26.03  ? 103 VAL A N   1 
ATOM   805   C CA  . VAL A 1 102 ? 148.633 158.795 122.257 1.00 24.09  ? 103 VAL A CA  1 
ATOM   806   C C   . VAL A 1 102 ? 149.167 159.827 121.277 1.00 25.64  ? 103 VAL A C   1 
ATOM   807   O O   . VAL A 1 102 ? 148.757 160.992 121.307 1.00 32.84  ? 103 VAL A O   1 
ATOM   808   C CB  . VAL A 1 102 ? 147.106 158.670 122.148 1.00 29.09  ? 103 VAL A CB  1 
ATOM   809   C CG1 . VAL A 1 102 ? 146.707 158.309 120.732 1.00 32.26  ? 103 VAL A CG1 1 
ATOM   810   C CG2 . VAL A 1 102 ? 146.582 157.641 123.133 1.00 28.46  ? 103 VAL A CG2 1 
ATOM   811   N N   . PHE A 1 103 ? 150.086 159.409 120.413 1.00 22.27  ? 104 PHE A N   1 
ATOM   812   C CA  . PHE A 1 103 ? 150.676 160.300 119.430 1.00 22.21  ? 104 PHE A CA  1 
ATOM   813   C C   . PHE A 1 103 ? 150.618 159.651 118.056 1.00 26.06  ? 104 PHE A C   1 
ATOM   814   O O   . PHE A 1 103 ? 150.360 158.453 117.919 1.00 24.63  ? 104 PHE A O   1 
ATOM   815   C CB  . PHE A 1 103 ? 152.126 160.678 119.787 1.00 21.52  ? 104 PHE A CB  1 
ATOM   816   C CG  . PHE A 1 103 ? 153.032 159.502 120.029 1.00 21.53  ? 104 PHE A CG  1 
ATOM   817   C CD1 . PHE A 1 103 ? 153.073 158.881 121.264 1.00 20.14  ? 104 PHE A CD1 1 
ATOM   818   C CD2 . PHE A 1 103 ? 153.860 159.032 119.024 1.00 20.51  ? 104 PHE A CD2 1 
ATOM   819   C CE1 . PHE A 1 103 ? 153.906 157.808 121.485 1.00 15.83  ? 104 PHE A CE1 1 
ATOM   820   C CE2 . PHE A 1 103 ? 154.697 157.958 119.242 1.00 19.30  ? 104 PHE A CE2 1 
ATOM   821   C CZ  . PHE A 1 103 ? 154.720 157.347 120.474 1.00 16.42  ? 104 PHE A CZ  1 
ATOM   822   N N   . ASP A 1 104 ? 150.843 160.473 117.034 1.00 31.89  ? 105 ASP A N   1 
ATOM   823   C CA  . ASP A 1 104 ? 150.810 159.998 115.659 1.00 32.09  ? 105 ASP A CA  1 
ATOM   824   C C   . ASP A 1 104 ? 151.916 158.978 115.417 1.00 34.35  ? 105 ASP A C   1 
ATOM   825   O O   . ASP A 1 104 ? 153.082 159.219 115.743 1.00 33.46  ? 105 ASP A O   1 
ATOM   826   C CB  . ASP A 1 104 ? 150.958 161.180 114.701 1.00 36.66  ? 105 ASP A CB  1 
ATOM   827   C CG  . ASP A 1 104 ? 150.175 160.995 113.420 1.00 50.68  ? 105 ASP A CG  1 
ATOM   828   O OD1 . ASP A 1 104 ? 148.948 161.228 113.432 1.00 56.74  ? 105 ASP A OD1 1 
ATOM   829   O OD2 . ASP A 1 104 ? 150.785 160.618 112.398 1.00 52.87  ? 105 ASP A OD2 1 
ATOM   830   N N   . GLY A 1 105 ? 151.546 157.839 114.839 1.00 32.38  ? 106 GLY A N   1 
ATOM   831   C CA  . GLY A 1 105 ? 152.515 156.804 114.538 1.00 30.84  ? 106 GLY A CA  1 
ATOM   832   C C   . GLY A 1 105 ? 153.014 156.025 115.733 1.00 31.25  ? 106 GLY A C   1 
ATOM   833   O O   . GLY A 1 105 ? 154.172 155.602 115.745 1.00 32.48  ? 106 GLY A O   1 
ATOM   834   N N   . LEU A 1 106 ? 152.170 155.825 116.744 1.00 26.56  ? 107 LEU A N   1 
ATOM   835   C CA  . LEU A 1 106 ? 152.580 155.079 117.930 1.00 22.95  ? 107 LEU A CA  1 
ATOM   836   C C   . LEU A 1 106 ? 152.873 153.622 117.589 1.00 28.11  ? 107 LEU A C   1 
ATOM   837   O O   . LEU A 1 106 ? 153.923 153.079 117.966 1.00 33.81  ? 107 LEU A O   1 
ATOM   838   C CB  . LEU A 1 106 ? 151.486 155.193 118.996 1.00 20.07  ? 107 LEU A CB  1 
ATOM   839   C CG  . LEU A 1 106 ? 151.580 154.560 120.385 1.00 18.70  ? 107 LEU A CG  1 
ATOM   840   C CD1 . LEU A 1 106 ? 150.656 155.307 121.320 1.00 17.27  ? 107 LEU A CD1 1 
ATOM   841   C CD2 . LEU A 1 106 ? 151.198 153.093 120.365 1.00 21.61  ? 107 LEU A CD2 1 
ATOM   842   N N   . PHE A 1 107 ? 151.956 152.975 116.865 1.00 27.69  ? 108 PHE A N   1 
ATOM   843   C CA  . PHE A 1 107 ? 152.113 151.556 116.567 1.00 26.11  ? 108 PHE A CA  1 
ATOM   844   C C   . PHE A 1 107 ? 153.320 151.303 115.677 1.00 28.98  ? 108 PHE A C   1 
ATOM   845   O O   . PHE A 1 107 ? 154.001 150.288 115.832 1.00 29.37  ? 108 PHE A O   1 
ATOM   846   C CB  . PHE A 1 107 ? 150.847 151.004 115.917 1.00 26.75  ? 108 PHE A CB  1 
ATOM   847   C CG  . PHE A 1 107 ? 150.724 149.511 116.010 1.00 26.89  ? 108 PHE A CG  1 
ATOM   848   C CD1 . PHE A 1 107 ? 150.866 148.867 117.226 1.00 28.23  ? 108 PHE A CD1 1 
ATOM   849   C CD2 . PHE A 1 107 ? 150.476 148.750 114.882 1.00 26.30  ? 108 PHE A CD2 1 
ATOM   850   C CE1 . PHE A 1 107 ? 150.755 147.495 117.316 1.00 27.89  ? 108 PHE A CE1 1 
ATOM   851   C CE2 . PHE A 1 107 ? 150.368 147.379 114.967 1.00 26.66  ? 108 PHE A CE2 1 
ATOM   852   C CZ  . PHE A 1 107 ? 150.506 146.752 116.185 1.00 27.19  ? 108 PHE A CZ  1 
ATOM   853   N N   . GLU A 1 108 ? 153.597 152.202 114.731 1.00 28.00  ? 109 GLU A N   1 
ATOM   854   C CA  . GLU A 1 108 ? 154.778 152.040 113.890 1.00 27.74  ? 109 GLU A CA  1 
ATOM   855   C C   . GLU A 1 108 ? 156.059 152.150 114.709 1.00 28.52  ? 109 GLU A C   1 
ATOM   856   O O   . GLU A 1 108 ? 157.031 151.426 114.460 1.00 31.46  ? 109 GLU A O   1 
ATOM   857   C CB  . GLU A 1 108 ? 154.764 153.074 112.766 1.00 31.42  ? 109 GLU A CB  1 
ATOM   858   C CG  . GLU A 1 108 ? 153.764 152.774 111.664 1.00 40.77  ? 109 GLU A CG  1 
ATOM   859   C CD  . GLU A 1 108 ? 152.412 153.413 111.913 1.00 48.98  ? 109 GLU A CD  1 
ATOM   860   O OE1 . GLU A 1 108 ? 151.639 152.873 112.731 1.00 43.57  ? 109 GLU A OE1 1 
ATOM   861   O OE2 . GLU A 1 108 ? 152.121 154.456 111.292 1.00 54.44  ? 109 GLU A OE2 1 
ATOM   862   N N   . PHE A 1 109 ? 156.078 153.056 115.689 1.00 25.85  ? 110 PHE A N   1 
ATOM   863   C CA  . PHE A 1 109 ? 157.217 153.159 116.596 1.00 23.01  ? 110 PHE A CA  1 
ATOM   864   C C   . PHE A 1 109 ? 157.419 151.856 117.358 1.00 24.08  ? 110 PHE A C   1 
ATOM   865   O O   . PHE A 1 109 ? 158.543 151.337 117.450 1.00 25.00  ? 110 PHE A O   1 
ATOM   866   C CB  . PHE A 1 109 ? 156.992 154.331 117.555 1.00 22.57  ? 110 PHE A CB  1 
ATOM   867   C CG  . PHE A 1 109 ? 158.089 154.522 118.563 1.00 23.98  ? 110 PHE A CG  1 
ATOM   868   C CD1 . PHE A 1 109 ? 159.263 155.163 118.216 1.00 22.97  ? 110 PHE A CD1 1 
ATOM   869   C CD2 . PHE A 1 109 ? 157.936 154.077 119.864 1.00 22.88  ? 110 PHE A CD2 1 
ATOM   870   C CE1 . PHE A 1 109 ? 160.268 155.343 119.142 1.00 20.74  ? 110 PHE A CE1 1 
ATOM   871   C CE2 . PHE A 1 109 ? 158.938 154.254 120.793 1.00 18.34  ? 110 PHE A CE2 1 
ATOM   872   C CZ  . PHE A 1 109 ? 160.104 154.888 120.431 1.00 18.78  ? 110 PHE A CZ  1 
ATOM   873   N N   . CYS A 1 110 ? 156.329 151.300 117.897 1.00 23.62  ? 111 CYS A N   1 
ATOM   874   C CA  . CYS A 1 110 ? 156.424 150.027 118.605 1.00 22.21  ? 111 CYS A CA  1 
ATOM   875   C C   . CYS A 1 110 ? 156.903 148.915 117.680 1.00 24.50  ? 111 CYS A C   1 
ATOM   876   O O   . CYS A 1 110 ? 157.729 148.082 118.072 1.00 24.49  ? 111 CYS A O   1 
ATOM   877   C CB  . CYS A 1 110 ? 155.072 149.665 119.218 1.00 23.82  ? 111 CYS A CB  1 
ATOM   878   S SG  . CYS A 1 110 ? 154.427 150.875 120.390 1.00 33.77  ? 111 CYS A SG  1 
ATOM   879   N N   . GLN A 1 111 ? 156.396 148.891 116.445 1.00 27.30  ? 112 GLN A N   1 
ATOM   880   C CA  . GLN A 1 111 ? 156.780 147.860 115.489 1.00 25.13  ? 112 GLN A CA  1 
ATOM   881   C C   . GLN A 1 111 ? 158.263 147.930 115.163 1.00 21.64  ? 112 GLN A C   1 
ATOM   882   O O   . GLN A 1 111 ? 158.937 146.900 115.112 1.00 24.11  ? 112 GLN A O   1 
ATOM   883   C CB  . GLN A 1 111 ? 155.954 147.992 114.211 1.00 25.48  ? 112 GLN A CB  1 
ATOM   884   C CG  . GLN A 1 111 ? 154.499 147.609 114.358 1.00 25.98  ? 112 GLN A CG  1 
ATOM   885   C CD  . GLN A 1 111 ? 153.790 147.518 113.027 1.00 29.70  ? 112 GLN A CD  1 
ATOM   886   O OE1 . GLN A 1 111 ? 153.586 148.524 112.351 1.00 32.77  ? 112 GLN A OE1 1 
ATOM   887   N NE2 . GLN A 1 111 ? 153.410 146.309 112.640 1.00 31.12  ? 112 GLN A NE2 1 
ATOM   888   N N   . LEU A 1 112 ? 158.791 149.133 114.938 1.00 22.84  ? 113 LEU A N   1 
ATOM   889   C CA  . LEU A 1 112 ? 160.210 149.263 114.618 1.00 23.74  ? 113 LEU A CA  1 
ATOM   890   C C   . LEU A 1 112 ? 161.082 148.861 115.803 1.00 23.10  ? 113 LEU A C   1 
ATOM   891   O O   . LEU A 1 112 ? 162.063 148.116 115.646 1.00 27.12  ? 113 LEU A O   1 
ATOM   892   C CB  . LEU A 1 112 ? 160.516 150.695 114.182 1.00 24.47  ? 113 LEU A CB  1 
ATOM   893   C CG  . LEU A 1 112 ? 159.952 151.100 112.821 1.00 27.11  ? 113 LEU A CG  1 
ATOM   894   C CD1 . LEU A 1 112 ? 160.187 152.577 112.560 1.00 27.69  ? 113 LEU A CD1 1 
ATOM   895   C CD2 . LEU A 1 112 ? 160.563 150.247 111.728 1.00 28.04  ? 113 LEU A CD2 1 
ATOM   896   N N   . SER A 1 113 ? 160.730 149.337 117.003 1.00 22.06  ? 114 SER A N   1 
ATOM   897   C CA  . SER A 1 113 ? 161.514 148.996 118.186 1.00 17.73  ? 114 SER A CA  1 
ATOM   898   C C   . SER A 1 113 ? 161.513 147.494 118.439 1.00 17.32  ? 114 SER A C   1 
ATOM   899   O O   . SER A 1 113 ? 162.549 146.915 118.781 1.00 17.50  ? 114 SER A O   1 
ATOM   900   C CB  . SER A 1 113 ? 160.978 149.744 119.405 1.00 20.37  ? 114 SER A CB  1 
ATOM   901   O OG  . SER A 1 113 ? 160.506 151.030 119.045 1.00 22.11  ? 114 SER A OG  1 
ATOM   902   N N   . THR A 1 114 ? 160.358 146.843 118.272 1.00 19.38  ? 115 THR A N   1 
ATOM   903   C CA  . THR A 1 114 ? 160.277 145.402 118.486 1.00 17.94  ? 115 THR A CA  1 
ATOM   904   C C   . THR A 1 114 ? 160.994 144.632 117.384 1.00 16.19  ? 115 THR A C   1 
ATOM   905   O O   . THR A 1 114 ? 161.648 143.616 117.653 1.00 16.66  ? 115 THR A O   1 
ATOM   906   C CB  . THR A 1 114 ? 158.812 144.977 118.571 1.00 21.51  ? 115 THR A CB  1 
ATOM   907   O OG1 . THR A 1 114 ? 158.144 145.765 119.564 1.00 23.30  ? 115 THR A OG1 1 
ATOM   908   C CG2 . THR A 1 114 ? 158.700 143.510 118.940 1.00 23.05  ? 115 THR A CG2 1 
ATOM   909   N N   . GLY A 1 115 ? 160.876 145.095 116.139 1.00 18.37  ? 116 GLY A N   1 
ATOM   910   C CA  . GLY A 1 115 ? 161.477 144.383 115.029 1.00 18.56  ? 116 GLY A CA  1 
ATOM   911   C C   . GLY A 1 115 ? 162.988 144.388 115.081 1.00 17.74  ? 116 GLY A C   1 
ATOM   912   O O   . GLY A 1 115 ? 163.626 143.391 114.743 1.00 22.60  ? 116 GLY A O   1 
ATOM   913   N N   . GLY A 1 116 ? 163.584 145.501 115.513 1.00 14.94  ? 117 GLY A N   1 
ATOM   914   C CA  . GLY A 1 116 ? 165.032 145.519 115.661 1.00 13.18  ? 117 GLY A CA  1 
ATOM   915   C C   . GLY A 1 116 ? 165.531 144.465 116.634 1.00 12.76  ? 117 GLY A C   1 
ATOM   916   O O   . GLY A 1 116 ? 166.447 143.697 116.327 1.00 14.16  ? 117 GLY A O   1 
ATOM   917   N N   . SER A 1 117 ? 164.908 144.395 117.814 1.00 13.01  ? 118 SER A N   1 
ATOM   918   C CA  . SER A 1 117 ? 165.322 143.431 118.830 1.00 11.76  ? 118 SER A CA  1 
ATOM   919   C C   . SER A 1 117 ? 165.076 141.998 118.379 1.00 13.67  ? 118 SER A C   1 
ATOM   920   O O   . SER A 1 117 ? 165.928 141.124 118.579 1.00 16.08  ? 118 SER A O   1 
ATOM   921   C CB  . SER A 1 117 ? 164.589 143.705 120.141 1.00 13.78  ? 118 SER A CB  1 
ATOM   922   O OG  . SER A 1 117 ? 164.661 145.073 120.497 1.00 12.22  ? 118 SER A OG  1 
ATOM   923   N N   . VAL A 1 118 ? 163.917 141.732 117.772 1.00 16.28  ? 119 VAL A N   1 
ATOM   924   C CA  . VAL A 1 118 ? 163.605 140.367 117.361 1.00 14.28  ? 119 VAL A CA  1 
ATOM   925   C C   . VAL A 1 118 ? 164.521 139.924 116.227 1.00 17.94  ? 119 VAL A C   1 
ATOM   926   O O   . VAL A 1 118 ? 164.970 138.772 116.191 1.00 23.36  ? 119 VAL A O   1 
ATOM   927   C CB  . VAL A 1 118 ? 162.119 140.250 116.982 1.00 16.64  ? 119 VAL A CB  1 
ATOM   928   C CG1 . VAL A 1 118 ? 161.828 138.886 116.390 1.00 23.54  ? 119 VAL A CG1 1 
ATOM   929   C CG2 . VAL A 1 118 ? 161.251 140.482 118.203 1.00 14.81  ? 119 VAL A CG2 1 
ATOM   930   N N   . ALA A 1 119 ? 164.826 140.825 115.289 1.00 16.48  ? 120 ALA A N   1 
ATOM   931   C CA  . ALA A 1 119 ? 165.758 140.491 114.220 1.00 16.78  ? 120 ALA A CA  1 
ATOM   932   C C   . ALA A 1 119 ? 167.158 140.238 114.763 1.00 15.86  ? 120 ALA A C   1 
ATOM   933   O O   . ALA A 1 119 ? 167.851 139.328 114.297 1.00 18.34  ? 120 ALA A O   1 
ATOM   934   C CB  . ALA A 1 119 ? 165.777 141.604 113.176 1.00 22.08  ? 120 ALA A CB  1 
ATOM   935   N N   . GLY A 1 120 ? 167.594 141.029 115.746 1.00 15.77  ? 121 GLY A N   1 
ATOM   936   C CA  . GLY A 1 120 ? 168.884 140.766 116.363 1.00 15.24  ? 121 GLY A CA  1 
ATOM   937   C C   . GLY A 1 120 ? 168.935 139.417 117.054 1.00 16.10  ? 121 GLY A C   1 
ATOM   938   O O   . GLY A 1 120 ? 169.924 138.686 116.944 1.00 18.13  ? 121 GLY A O   1 
ATOM   939   N N   . ALA A 1 121 ? 167.866 139.067 117.775 1.00 18.67  ? 122 ALA A N   1 
ATOM   940   C CA  . ALA A 1 121 ? 167.804 137.765 118.432 1.00 16.70  ? 122 ALA A CA  1 
ATOM   941   C C   . ALA A 1 121 ? 167.825 136.629 117.417 1.00 18.60  ? 122 ALA A C   1 
ATOM   942   O O   . ALA A 1 121 ? 168.488 135.608 117.631 1.00 19.66  ? 122 ALA A O   1 
ATOM   943   C CB  . ALA A 1 121 ? 166.557 137.678 119.309 1.00 14.46  ? 122 ALA A CB  1 
ATOM   944   N N   . VAL A 1 122 ? 167.101 136.786 116.306 1.00 19.63  ? 123 VAL A N   1 
ATOM   945   C CA  . VAL A 1 122 ? 167.109 135.768 115.257 1.00 21.46  ? 123 VAL A CA  1 
ATOM   946   C C   . VAL A 1 122 ? 168.504 135.623 114.663 1.00 24.65  ? 123 VAL A C   1 
ATOM   947   O O   . VAL A 1 122 ? 168.977 134.508 114.415 1.00 26.40  ? 123 VAL A O   1 
ATOM   948   C CB  . VAL A 1 122 ? 166.070 136.107 114.173 1.00 26.19  ? 123 VAL A CB  1 
ATOM   949   C CG1 . VAL A 1 122 ? 166.277 135.238 112.949 1.00 36.46  ? 123 VAL A CG1 1 
ATOM   950   C CG2 . VAL A 1 122 ? 164.667 135.938 114.711 1.00 27.17  ? 123 VAL A CG2 1 
ATOM   951   N N   . LYS A 1 123 ? 169.180 136.747 114.418 1.00 26.34  ? 124 LYS A N   1 
ATOM   952   C CA  . LYS A 1 123 ? 170.533 136.703 113.873 1.00 24.26  ? 124 LYS A CA  1 
ATOM   953   C C   . LYS A 1 123 ? 171.488 135.991 114.822 1.00 24.17  ? 124 LYS A C   1 
ATOM   954   O O   . LYS A 1 123 ? 172.352 135.224 114.385 1.00 25.73  ? 124 LYS A O   1 
ATOM   955   C CB  . LYS A 1 123 ? 171.021 138.122 113.583 1.00 23.26  ? 124 LYS A CB  1 
ATOM   956   C CG  . LYS A 1 123 ? 172.263 138.196 112.721 1.00 29.46  ? 124 LYS A CG  1 
ATOM   957   C CD  . LYS A 1 123 ? 171.910 138.226 111.250 1.00 29.67  ? 124 LYS A CD  1 
ATOM   958   C CE  . LYS A 1 123 ? 173.155 138.339 110.396 1.00 34.48  ? 124 LYS A CE  1 
ATOM   959   N NZ  . LYS A 1 123 ? 172.853 138.114 108.958 1.00 42.20  ? 124 LYS A NZ  1 
ATOM   960   N N   . LEU A 1 124 ? 171.353 136.240 116.127 1.00 24.26  ? 125 LEU A N   1 
ATOM   961   C CA  . LEU A 1 124 ? 172.200 135.553 117.099 1.00 20.27  ? 125 LEU A CA  1 
ATOM   962   C C   . LEU A 1 124 ? 171.858 134.072 117.204 1.00 23.34  ? 125 LEU A C   1 
ATOM   963   O O   . LEU A 1 124 ? 172.738 133.255 117.495 1.00 25.69  ? 125 LEU A O   1 
ATOM   964   C CB  . LEU A 1 124 ? 172.077 136.217 118.469 1.00 16.75  ? 125 LEU A CB  1 
ATOM   965   C CG  . LEU A 1 124 ? 172.737 137.582 118.644 1.00 14.79  ? 125 LEU A CG  1 
ATOM   966   C CD1 . LEU A 1 124 ? 172.098 138.324 119.800 1.00 13.16  ? 125 LEU A CD1 1 
ATOM   967   C CD2 . LEU A 1 124 ? 174.229 137.428 118.861 1.00 13.57  ? 125 LEU A CD2 1 
ATOM   968   N N   . ASN A 1 125 ? 170.590 133.709 116.988 1.00 27.44  ? 126 ASN A N   1 
ATOM   969   C CA  . ASN A 1 125 ? 170.190 132.306 117.061 1.00 26.05  ? 126 ASN A CA  1 
ATOM   970   C C   . ASN A 1 125 ? 170.877 131.473 115.987 1.00 30.50  ? 126 ASN A C   1 
ATOM   971   O O   . ASN A 1 125 ? 171.330 130.355 116.254 1.00 35.56  ? 126 ASN A O   1 
ATOM   972   C CB  . ASN A 1 125 ? 168.673 132.187 116.928 1.00 27.96  ? 126 ASN A CB  1 
ATOM   973   C CG  . ASN A 1 125 ? 167.968 132.196 118.264 1.00 26.41  ? 126 ASN A CG  1 
ATOM   974   O OD1 . ASN A 1 125 ? 168.593 132.028 119.308 1.00 28.72  ? 126 ASN A OD1 1 
ATOM   975   N ND2 . ASN A 1 125 ? 166.657 132.392 118.238 1.00 22.25  ? 126 ASN A ND2 1 
ATOM   976   N N   . ARG A 1 126 ? 170.959 131.997 114.768 1.00 35.33  ? 127 ARG A N   1 
ATOM   977   C CA  . ARG A 1 126 ? 171.530 131.277 113.638 1.00 41.55  ? 127 ARG A CA  1 
ATOM   978   C C   . ARG A 1 126 ? 173.050 131.325 113.601 1.00 39.69  ? 127 ARG A C   1 
ATOM   979   O O   . ARG A 1 126 ? 173.636 130.908 112.597 1.00 42.55  ? 127 ARG A O   1 
ATOM   980   C CB  . ARG A 1 126 ? 170.968 131.829 112.328 1.00 41.74  ? 127 ARG A CB  1 
ATOM   981   C CG  . ARG A 1 126 ? 169.460 131.817 112.264 1.00 51.44  ? 127 ARG A CG  1 
ATOM   982   C CD  . ARG A 1 126 ? 168.950 132.608 111.079 1.00 61.61  ? 127 ARG A CD  1 
ATOM   983   N NE  . ARG A 1 126 ? 167.494 132.625 111.041 1.00 68.88  ? 127 ARG A NE  1 
ATOM   984   C CZ  . ARG A 1 126 ? 166.775 132.695 109.930 1.00 82.66  ? 127 ARG A CZ  1 
ATOM   985   N NH1 . ARG A 1 126 ? 167.348 132.774 108.740 1.00 85.43  ? 127 ARG A NH1 1 
ATOM   986   N NH2 . ARG A 1 126 ? 165.448 132.682 110.014 1.00 85.76  ? 127 ARG A NH2 1 
ATOM   987   N N   . GLN A 1 127 ? 173.691 131.825 114.658 1.00 34.08  ? 128 GLN A N   1 
ATOM   988   C CA  . GLN A 1 127 ? 175.148 131.879 114.755 1.00 32.93  ? 128 GLN A CA  1 
ATOM   989   C C   . GLN A 1 127 ? 175.764 132.678 113.612 1.00 34.13  ? 128 GLN A C   1 
ATOM   990   O O   . GLN A 1 127 ? 176.866 132.374 113.151 1.00 36.44  ? 128 GLN A O   1 
ATOM   991   C CB  . GLN A 1 127 ? 175.755 130.474 114.806 1.00 35.94  ? 128 GLN A CB  1 
ATOM   992   C CG  . GLN A 1 127 ? 175.302 129.641 115.988 1.00 36.71  ? 128 GLN A CG  1 
ATOM   993   C CD  . GLN A 1 127 ? 176.401 128.745 116.512 1.00 47.90  ? 128 GLN A CD  1 
ATOM   994   O OE1 . GLN A 1 127 ? 177.507 129.202 116.796 1.00 50.03  ? 128 GLN A OE1 1 
ATOM   995   N NE2 . GLN A 1 127 ? 176.104 127.458 116.640 1.00 51.76  ? 128 GLN A NE2 1 
ATOM   996   N N   . GLN A 1 128 ? 175.056 133.704 113.144 1.00 34.77  ? 129 GLN A N   1 
ATOM   997   C CA  . GLN A 1 128 ? 175.553 134.550 112.070 1.00 33.23  ? 129 GLN A CA  1 
ATOM   998   C C   . GLN A 1 128 ? 176.238 135.812 112.573 1.00 33.02  ? 129 GLN A C   1 
ATOM   999   O O   . GLN A 1 128 ? 176.791 136.560 111.762 1.00 38.51  ? 129 GLN A O   1 
ATOM   1000  C CB  . GLN A 1 128 ? 174.408 134.932 111.128 1.00 30.82  ? 129 GLN A CB  1 
ATOM   1001  C CG  . GLN A 1 128 ? 174.246 133.994 109.948 1.00 33.80  ? 129 GLN A CG  1 
ATOM   1002  C CD  . GLN A 1 128 ? 172.841 134.005 109.386 1.00 42.70  ? 129 GLN A CD  1 
ATOM   1003  O OE1 . GLN A 1 128 ? 171.893 134.400 110.063 1.00 44.86  ? 129 GLN A OE1 1 
ATOM   1004  N NE2 . GLN A 1 128 ? 172.698 133.570 108.141 1.00 50.23  ? 129 GLN A NE2 1 
ATOM   1005  N N   . THR A 1 129 ? 176.217 136.065 113.879 1.00 31.16  ? 130 THR A N   1 
ATOM   1006  C CA  . THR A 1 129 ? 176.890 137.223 114.443 1.00 27.35  ? 130 THR A CA  1 
ATOM   1007  C C   . THR A 1 129 ? 177.252 136.931 115.890 1.00 29.90  ? 130 THR A C   1 
ATOM   1008  O O   . THR A 1 129 ? 176.680 136.043 116.528 1.00 34.10  ? 130 THR A O   1 
ATOM   1009  C CB  . THR A 1 129 ? 176.023 138.486 114.350 1.00 26.14  ? 130 THR A CB  1 
ATOM   1010  O OG1 . THR A 1 129 ? 176.814 139.634 114.674 1.00 26.94  ? 130 THR A OG1 1 
ATOM   1011  C CG2 . THR A 1 129 ? 174.851 138.407 115.309 1.00 23.25  ? 130 THR A CG2 1 
ATOM   1012  N N   . ASP A 1 130 ? 178.223 137.687 116.399 1.00 28.44  ? 131 ASP A N   1 
ATOM   1013  C CA  . ASP A 1 130 ? 178.635 137.589 117.793 1.00 22.54  ? 131 ASP A CA  1 
ATOM   1014  C C   . ASP A 1 130 ? 178.022 138.668 118.671 1.00 22.60  ? 131 ASP A C   1 
ATOM   1015  O O   . ASP A 1 130 ? 177.889 138.464 119.881 1.00 22.02  ? 131 ASP A O   1 
ATOM   1016  C CB  . ASP A 1 130 ? 180.161 137.660 117.901 1.00 27.84  ? 131 ASP A CB  1 
ATOM   1017  C CG  . ASP A 1 130 ? 180.853 136.630 117.032 1.00 39.25  ? 131 ASP A CG  1 
ATOM   1018  O OD1 . ASP A 1 130 ? 180.149 135.838 116.374 1.00 44.98  ? 131 ASP A OD1 1 
ATOM   1019  O OD2 . ASP A 1 130 ? 182.101 136.610 117.007 1.00 40.30  ? 131 ASP A OD2 1 
ATOM   1020  N N   . MET A 1 131 ? 177.652 139.808 118.092 1.00 23.57  ? 132 MET A N   1 
ATOM   1021  C CA  . MET A 1 131 ? 176.970 140.873 118.808 1.00 16.48  ? 132 MET A CA  1 
ATOM   1022  C C   . MET A 1 131 ? 175.877 141.444 117.920 1.00 14.47  ? 132 MET A C   1 
ATOM   1023  O O   . MET A 1 131 ? 175.966 141.393 116.692 1.00 16.96  ? 132 MET A O   1 
ATOM   1024  C CB  . MET A 1 131 ? 177.939 141.985 119.229 1.00 16.19  ? 132 MET A CB  1 
ATOM   1025  C CG  . MET A 1 131 ? 178.326 141.948 120.695 1.00 17.90  ? 132 MET A CG  1 
ATOM   1026  S SD  . MET A 1 131 ? 179.872 142.800 121.044 1.00 35.42  ? 132 MET A SD  1 
ATOM   1027  C CE  . MET A 1 131 ? 181.012 141.870 120.028 1.00 24.41  ? 132 MET A CE  1 
ATOM   1028  N N   . ALA A 1 132 ? 174.837 141.980 118.554 1.00 14.26  ? 133 ALA A N   1 
ATOM   1029  C CA  . ALA A 1 132 ? 173.746 142.641 117.851 1.00 11.29  ? 133 ALA A CA  1 
ATOM   1030  C C   . ALA A 1 132 ? 173.330 143.865 118.648 1.00 11.53  ? 133 ALA A C   1 
ATOM   1031  O O   . ALA A 1 132 ? 173.109 143.770 119.858 1.00 12.12  ? 133 ALA A O   1 
ATOM   1032  C CB  . ALA A 1 132 ? 172.555 141.701 117.655 1.00 11.61  ? 133 ALA A CB  1 
ATOM   1033  N N   . VAL A 1 133 ? 173.221 145.007 117.974 1.00 11.38  ? 134 VAL A N   1 
ATOM   1034  C CA  . VAL A 1 133 ? 172.943 146.283 118.619 1.00 10.93  ? 134 VAL A CA  1 
ATOM   1035  C C   . VAL A 1 133 ? 171.633 146.842 118.082 1.00 10.77  ? 134 VAL A C   1 
ATOM   1036  O O   . VAL A 1 133 ? 171.356 146.763 116.880 1.00 10.09  ? 134 VAL A O   1 
ATOM   1037  C CB  . VAL A 1 133 ? 174.090 147.293 118.407 1.00 9.92   ? 134 VAL A CB  1 
ATOM   1038  C CG1 . VAL A 1 133 ? 173.944 148.462 119.351 1.00 9.41   ? 134 VAL A CG1 1 
ATOM   1039  C CG2 . VAL A 1 133 ? 175.434 146.619 118.602 1.00 9.60   ? 134 VAL A CG2 1 
ATOM   1040  N N   . ASN A 1 134 ? 170.823 147.397 118.984 1.00 9.36   ? 135 ASN A N   1 
ATOM   1041  C CA  . ASN A 1 134 ? 169.577 148.067 118.616 1.00 8.92   ? 135 ASN A CA  1 
ATOM   1042  C C   . ASN A 1 134 ? 169.293 149.096 119.705 1.00 9.07   ? 135 ASN A C   1 
ATOM   1043  O O   . ASN A 1 134 ? 168.809 148.741 120.782 1.00 10.26  ? 135 ASN A O   1 
ATOM   1044  C CB  . ASN A 1 134 ? 168.433 147.072 118.473 1.00 9.35   ? 135 ASN A CB  1 
ATOM   1045  C CG  . ASN A 1 134 ? 167.144 147.723 118.006 1.00 9.24   ? 135 ASN A CG  1 
ATOM   1046  O OD1 . ASN A 1 134 ? 167.107 148.389 116.975 1.00 9.57   ? 135 ASN A OD1 1 
ATOM   1047  N ND2 . ASN A 1 134 ? 166.078 147.529 118.768 1.00 10.36  ? 135 ASN A ND2 1 
ATOM   1048  N N   . TRP A 1 135 ? 169.601 150.362 119.423 1.00 8.81   ? 136 TRP A N   1 
ATOM   1049  C CA  . TRP A 1 135 ? 169.389 151.419 120.402 1.00 7.68   ? 136 TRP A CA  1 
ATOM   1050  C C   . TRP A 1 135 ? 167.949 151.909 120.447 1.00 9.57   ? 136 TRP A C   1 
ATOM   1051  O O   . TRP A 1 135 ? 167.585 152.618 121.391 1.00 11.13  ? 136 TRP A O   1 
ATOM   1052  C CB  . TRP A 1 135 ? 170.328 152.595 120.122 1.00 7.98   ? 136 TRP A CB  1 
ATOM   1053  C CG  . TRP A 1 135 ? 171.790 152.257 120.252 1.00 7.19   ? 136 TRP A CG  1 
ATOM   1054  C CD1 . TRP A 1 135 ? 172.762 152.479 119.325 1.00 7.72   ? 136 TRP A CD1 1 
ATOM   1055  C CD2 . TRP A 1 135 ? 172.440 151.642 121.373 1.00 6.79   ? 136 TRP A CD2 1 
ATOM   1056  N NE1 . TRP A 1 135 ? 173.973 152.040 119.793 1.00 7.91   ? 136 TRP A NE1 1 
ATOM   1057  C CE2 . TRP A 1 135 ? 173.802 151.522 121.049 1.00 7.75   ? 136 TRP A CE2 1 
ATOM   1058  C CE3 . TRP A 1 135 ? 172.002 151.183 122.619 1.00 7.57   ? 136 TRP A CE3 1 
ATOM   1059  C CZ2 . TRP A 1 135 ? 174.729 150.961 121.922 1.00 8.40   ? 136 TRP A CZ2 1 
ATOM   1060  C CZ3 . TRP A 1 135 ? 172.922 150.626 123.480 1.00 7.70   ? 136 TRP A CZ3 1 
ATOM   1061  C CH2 . TRP A 1 135 ? 174.269 150.520 123.130 1.00 8.26   ? 136 TRP A CH2 1 
ATOM   1062  N N   . ALA A 1 136 ? 167.124 151.551 119.461 1.00 9.35   ? 137 ALA A N   1 
ATOM   1063  C CA  . ALA A 1 136 ? 165.711 151.904 119.486 1.00 8.01   ? 137 ALA A CA  1 
ATOM   1064  C C   . ALA A 1 136 ? 164.895 150.989 120.387 1.00 12.30  ? 137 ALA A C   1 
ATOM   1065  O O   . ALA A 1 136 ? 163.766 151.342 120.743 1.00 16.47  ? 137 ALA A O   1 
ATOM   1066  C CB  . ALA A 1 136 ? 165.134 151.874 118.072 1.00 8.86   ? 137 ALA A CB  1 
ATOM   1067  N N   . GLY A 1 137 ? 165.432 149.829 120.758 1.00 13.12  ? 138 GLY A N   1 
ATOM   1068  C CA  . GLY A 1 137 ? 164.768 148.924 121.669 1.00 11.00  ? 138 GLY A CA  1 
ATOM   1069  C C   . GLY A 1 137 ? 165.176 149.170 123.108 1.00 11.87  ? 138 GLY A C   1 
ATOM   1070  O O   . GLY A 1 137 ? 165.870 150.132 123.437 1.00 16.32  ? 138 GLY A O   1 
ATOM   1071  N N   . GLY A 1 138 ? 164.730 148.275 123.977 1.00 12.23  ? 139 GLY A N   1 
ATOM   1072  C CA  . GLY A 1 138 ? 165.024 148.367 125.386 1.00 12.41  ? 139 GLY A CA  1 
ATOM   1073  C C   . GLY A 1 138 ? 163.931 148.956 126.245 1.00 16.79  ? 139 GLY A C   1 
ATOM   1074  O O   . GLY A 1 138 ? 164.235 149.517 127.303 1.00 19.21  ? 139 GLY A O   1 
ATOM   1075  N N   . LEU A 1 139 ? 162.672 148.852 125.828 1.00 19.91  ? 140 LEU A N   1 
ATOM   1076  C CA  . LEU A 1 139 ? 161.539 149.330 126.617 1.00 20.54  ? 140 LEU A CA  1 
ATOM   1077  C C   . LEU A 1 139 ? 161.160 148.224 127.594 1.00 18.43  ? 140 LEU A C   1 
ATOM   1078  O O   . LEU A 1 139 ? 160.437 147.290 127.244 1.00 19.44  ? 140 LEU A O   1 
ATOM   1079  C CB  . LEU A 1 139 ? 160.374 149.715 125.711 1.00 20.82  ? 140 LEU A CB  1 
ATOM   1080  C CG  . LEU A 1 139 ? 160.582 150.823 124.667 1.00 19.62  ? 140 LEU A CG  1 
ATOM   1081  C CD1 . LEU A 1 139 ? 161.434 151.959 125.219 1.00 16.69  ? 140 LEU A CD1 1 
ATOM   1082  C CD2 . LEU A 1 139 ? 161.166 150.292 123.368 1.00 18.48  ? 140 LEU A CD2 1 
ATOM   1083  N N   . HIS A 1 140 ? 161.651 148.333 128.828 1.00 15.38  ? 141 HIS A N   1 
ATOM   1084  C CA  . HIS A 1 140 ? 161.578 147.258 129.809 1.00 13.56  ? 141 HIS A CA  1 
ATOM   1085  C C   . HIS A 1 140 ? 160.492 147.465 130.856 1.00 14.53  ? 141 HIS A C   1 
ATOM   1086  O O   . HIS A 1 140 ? 160.443 146.715 131.834 1.00 15.11  ? 141 HIS A O   1 
ATOM   1087  C CB  . HIS A 1 140 ? 162.934 147.083 130.500 1.00 11.27  ? 141 HIS A CB  1 
ATOM   1088  C CG  . HIS A 1 140 ? 163.380 148.275 131.292 1.00 12.24  ? 141 HIS A CG  1 
ATOM   1089  N ND1 . HIS A 1 140 ? 163.095 149.571 130.922 1.00 13.31  ? 141 HIS A ND1 1 
ATOM   1090  C CD2 . HIS A 1 140 ? 164.099 148.363 132.436 1.00 12.19  ? 141 HIS A CD2 1 
ATOM   1091  C CE1 . HIS A 1 140 ? 163.615 150.404 131.804 1.00 12.44  ? 141 HIS A CE1 1 
ATOM   1092  N NE2 . HIS A 1 140 ? 164.229 149.696 132.733 1.00 10.87  ? 141 HIS A NE2 1 
ATOM   1093  N N   . HIS A 1 141 ? 159.620 148.455 130.680 1.00 16.73  ? 142 HIS A N   1 
ATOM   1094  C CA  . HIS A 1 141 ? 158.586 148.734 131.665 1.00 15.34  ? 142 HIS A CA  1 
ATOM   1095  C C   . HIS A 1 141 ? 157.206 148.246 131.253 1.00 19.95  ? 142 HIS A C   1 
ATOM   1096  O O   . HIS A 1 141 ? 156.328 148.136 132.113 1.00 24.95  ? 142 HIS A O   1 
ATOM   1097  C CB  . HIS A 1 141 ? 158.518 150.237 131.951 1.00 13.25  ? 142 HIS A CB  1 
ATOM   1098  C CG  . HIS A 1 141 ? 159.616 150.736 132.837 1.00 13.95  ? 142 HIS A CG  1 
ATOM   1099  N ND1 . HIS A 1 141 ? 159.933 150.141 134.038 1.00 12.87  ? 142 HIS A ND1 1 
ATOM   1100  C CD2 . HIS A 1 141 ? 160.471 151.775 132.696 1.00 12.79  ? 142 HIS A CD2 1 
ATOM   1101  C CE1 . HIS A 1 141 ? 160.935 150.792 134.599 1.00 11.09  ? 142 HIS A CE1 1 
ATOM   1102  N NE2 . HIS A 1 141 ? 161.280 151.788 133.805 1.00 11.23  ? 142 HIS A NE2 1 
ATOM   1103  N N   . ALA A 1 142 ? 156.996 147.951 129.973 1.00 17.67  ? 143 ALA A N   1 
ATOM   1104  C CA  . ALA A 1 142 ? 155.679 147.553 129.501 1.00 17.25  ? 143 ALA A CA  1 
ATOM   1105  C C   . ALA A 1 142 ? 155.276 146.208 130.087 1.00 21.32  ? 143 ALA A C   1 
ATOM   1106  O O   . ALA A 1 142 ? 156.095 145.292 130.203 1.00 22.04  ? 143 ALA A O   1 
ATOM   1107  C CB  . ALA A 1 142 ? 155.661 147.488 127.977 1.00 17.24  ? 143 ALA A CB  1 
ATOM   1108  N N   . LYS A 1 143 ? 154.003 146.091 130.451 1.00 23.99  ? 144 LYS A N   1 
ATOM   1109  C CA  . LYS A 1 143 ? 153.457 144.882 131.042 1.00 22.29  ? 144 LYS A CA  1 
ATOM   1110  C C   . LYS A 1 143 ? 152.749 144.051 129.976 1.00 23.82  ? 144 LYS A C   1 
ATOM   1111  O O   . LYS A 1 143 ? 152.702 144.408 128.798 1.00 25.60  ? 144 LYS A O   1 
ATOM   1112  C CB  . LYS A 1 143 ? 152.511 145.229 132.192 1.00 25.85  ? 144 LYS A CB  1 
ATOM   1113  C CG  . LYS A 1 143 ? 153.162 146.021 133.312 1.00 29.54  ? 144 LYS A CG  1 
ATOM   1114  C CD  . LYS A 1 143 ? 154.407 145.320 133.825 1.00 28.87  ? 144 LYS A CD  1 
ATOM   1115  C CE  . LYS A 1 143 ? 155.206 146.217 134.747 1.00 25.02  ? 144 LYS A CE  1 
ATOM   1116  N NZ  . LYS A 1 143 ? 154.711 146.144 136.145 1.00 28.95  ? 144 LYS A NZ  1 
ATOM   1117  N N   . LYS A 1 144 ? 152.190 142.919 130.406 1.00 26.22  ? 145 LYS A N   1 
ATOM   1118  C CA  . LYS A 1 144 ? 151.577 141.987 129.466 1.00 26.01  ? 145 LYS A CA  1 
ATOM   1119  C C   . LYS A 1 144 ? 150.357 142.593 128.787 1.00 28.35  ? 145 LYS A C   1 
ATOM   1120  O O   . LYS A 1 144 ? 150.156 142.405 127.583 1.00 28.02  ? 145 LYS A O   1 
ATOM   1121  C CB  . LYS A 1 144 ? 151.200 140.694 130.187 1.00 27.78  ? 145 LYS A CB  1 
ATOM   1122  C CG  . LYS A 1 144 ? 150.611 139.631 129.284 1.00 27.66  ? 145 LYS A CG  1 
ATOM   1123  C CD  . LYS A 1 144 ? 150.794 138.252 129.885 1.00 31.64  ? 145 LYS A CD  1 
ATOM   1124  C CE  . LYS A 1 144 ? 150.265 137.175 128.963 1.00 29.66  ? 145 LYS A CE  1 
ATOM   1125  N NZ  . LYS A 1 144 ? 150.894 135.860 129.247 1.00 34.40  ? 145 LYS A NZ  1 
ATOM   1126  N N   . SER A 1 145 ? 149.531 143.323 129.540 1.00 30.70  ? 146 SER A N   1 
ATOM   1127  C CA  . SER A 1 145 ? 148.287 143.864 129.009 1.00 28.47  ? 146 SER A CA  1 
ATOM   1128  C C   . SER A 1 145 ? 148.097 145.335 129.360 1.00 29.96  ? 146 SER A C   1 
ATOM   1129  O O   . SER A 1 145 ? 146.960 145.815 129.382 1.00 35.70  ? 146 SER A O   1 
ATOM   1130  C CB  . SER A 1 145 ? 147.092 143.048 129.506 1.00 32.15  ? 146 SER A CB  1 
ATOM   1131  O OG  . SER A 1 145 ? 146.055 143.020 128.542 1.00 39.33  ? 146 SER A OG  1 
ATOM   1132  N N   . GLU A 1 146 ? 149.177 146.060 129.638 1.00 27.86  ? 147 GLU A N   1 
ATOM   1133  C CA  . GLU A 1 146 ? 149.077 147.486 129.909 1.00 28.13  ? 147 GLU A CA  1 
ATOM   1134  C C   . GLU A 1 146 ? 150.430 148.136 129.667 1.00 28.26  ? 147 GLU A C   1 
ATOM   1135  O O   . GLU A 1 146 ? 151.463 147.465 129.613 1.00 28.24  ? 147 GLU A O   1 
ATOM   1136  C CB  . GLU A 1 146 ? 148.591 147.758 131.335 1.00 30.99  ? 147 GLU A CB  1 
ATOM   1137  C CG  . GLU A 1 146 ? 149.679 147.727 132.385 1.00 34.22  ? 147 GLU A CG  1 
ATOM   1138  C CD  . GLU A 1 146 ? 149.190 148.211 133.732 1.00 43.18  ? 147 GLU A CD  1 
ATOM   1139  O OE1 . GLU A 1 146 ? 147.996 148.012 134.035 1.00 50.89  ? 147 GLU A OE1 1 
ATOM   1140  O OE2 . GLU A 1 146 ? 149.997 148.791 134.488 1.00 44.11  ? 147 GLU A OE2 1 
ATOM   1141  N N   . ALA A 1 147 ? 150.406 149.457 129.523 1.00 27.75  ? 148 ALA A N   1 
ATOM   1142  C CA  . ALA A 1 147 ? 151.594 150.252 129.256 1.00 25.11  ? 148 ALA A CA  1 
ATOM   1143  C C   . ALA A 1 147 ? 152.104 150.893 130.540 1.00 27.48  ? 148 ALA A C   1 
ATOM   1144  O O   . ALA A 1 147 ? 151.326 151.249 131.428 1.00 30.97  ? 148 ALA A O   1 
ATOM   1145  C CB  . ALA A 1 147 ? 151.297 151.334 128.217 1.00 19.58  ? 148 ALA A CB  1 
ATOM   1146  N N   . SER A 1 148 ? 153.425 151.037 130.634 1.00 21.77  ? 149 SER A N   1 
ATOM   1147  C CA  . SER A 1 148 ? 154.037 151.620 131.818 1.00 20.76  ? 149 SER A CA  1 
ATOM   1148  C C   . SER A 1 148 ? 155.348 152.295 131.447 1.00 20.81  ? 149 SER A C   1 
ATOM   1149  O O   . SER A 1 148 ? 156.079 151.810 130.581 1.00 20.68  ? 149 SER A O   1 
ATOM   1150  C CB  . SER A 1 148 ? 154.289 150.558 132.894 1.00 24.58  ? 149 SER A CB  1 
ATOM   1151  O OG  . SER A 1 148 ? 153.095 149.880 133.238 1.00 31.28  ? 149 SER A OG  1 
ATOM   1152  N N   . GLY A 1 149 ? 155.629 153.421 132.101 1.00 20.05  ? 150 GLY A N   1 
ATOM   1153  C CA  . GLY A 1 149 ? 156.935 154.050 132.055 1.00 16.54  ? 150 GLY A CA  1 
ATOM   1154  C C   . GLY A 1 149 ? 157.449 154.426 130.682 1.00 18.66  ? 150 GLY A C   1 
ATOM   1155  O O   . GLY A 1 149 ? 158.604 154.133 130.360 1.00 20.76  ? 150 GLY A O   1 
ATOM   1156  N N   . PHE A 1 150 ? 156.607 155.070 129.871 1.00 20.46  ? 151 PHE A N   1 
ATOM   1157  C CA  . PHE A 1 150 ? 156.893 155.503 128.502 1.00 18.93  ? 151 PHE A CA  1 
ATOM   1158  C C   . PHE A 1 150 ? 156.953 154.344 127.515 1.00 19.23  ? 151 PHE A C   1 
ATOM   1159  O O   . PHE A 1 150 ? 157.328 154.551 126.356 1.00 18.71  ? 151 PHE A O   1 
ATOM   1160  C CB  . PHE A 1 150 ? 158.201 156.302 128.386 1.00 16.91  ? 151 PHE A CB  1 
ATOM   1161  C CG  . PHE A 1 150 ? 158.362 157.391 129.416 1.00 19.67  ? 151 PHE A CG  1 
ATOM   1162  C CD1 . PHE A 1 150 ? 157.266 158.005 129.995 1.00 21.75  ? 151 PHE A CD1 1 
ATOM   1163  C CD2 . PHE A 1 150 ? 159.626 157.803 129.799 1.00 16.29  ? 151 PHE A CD2 1 
ATOM   1164  C CE1 . PHE A 1 150 ? 157.431 159.000 130.935 1.00 19.65  ? 151 PHE A CE1 1 
ATOM   1165  C CE2 . PHE A 1 150 ? 159.793 158.797 130.736 1.00 13.16  ? 151 PHE A CE2 1 
ATOM   1166  C CZ  . PHE A 1 150 ? 158.697 159.395 131.303 1.00 14.92  ? 151 PHE A CZ  1 
ATOM   1167  N N   . CYS A 1 151 ? 156.592 153.133 127.932 1.00 18.06  ? 152 CYS A N   1 
ATOM   1168  C CA  . CYS A 1 151 ? 156.716 151.940 127.107 1.00 16.38  ? 152 CYS A CA  1 
ATOM   1169  C C   . CYS A 1 151 ? 155.351 151.301 126.903 1.00 18.91  ? 152 CYS A C   1 
ATOM   1170  O O   . CYS A 1 151 ? 154.558 151.198 127.842 1.00 20.28  ? 152 CYS A O   1 
ATOM   1171  C CB  . CYS A 1 151 ? 157.666 150.924 127.744 1.00 18.94  ? 152 CYS A CB  1 
ATOM   1172  S SG  . CYS A 1 151 ? 159.136 151.629 128.520 1.00 24.99  ? 152 CYS A SG  1 
ATOM   1173  N N   . TYR A 1 152 ? 155.086 150.868 125.672 1.00 19.88  ? 153 TYR A N   1 
ATOM   1174  C CA  . TYR A 1 152 ? 153.839 150.204 125.313 1.00 17.25  ? 153 TYR A CA  1 
ATOM   1175  C C   . TYR A 1 152 ? 154.020 148.719 125.041 1.00 18.56  ? 153 TYR A C   1 
ATOM   1176  O O   . TYR A 1 152 ? 153.243 147.899 125.537 1.00 20.92  ? 153 TYR A O   1 
ATOM   1177  C CB  . TYR A 1 152 ? 153.213 150.879 124.084 1.00 17.44  ? 153 TYR A CB  1 
ATOM   1178  C CG  . TYR A 1 152 ? 153.237 152.388 124.126 1.00 19.44  ? 153 TYR A CG  1 
ATOM   1179  C CD1 . TYR A 1 152 ? 154.326 153.100 123.646 1.00 18.15  ? 153 TYR A CD1 1 
ATOM   1180  C CD2 . TYR A 1 152 ? 152.168 153.102 124.643 1.00 20.31  ? 153 TYR A CD2 1 
ATOM   1181  C CE1 . TYR A 1 152 ? 154.351 154.473 123.685 1.00 17.94  ? 153 TYR A CE1 1 
ATOM   1182  C CE2 . TYR A 1 152 ? 152.185 154.476 124.683 1.00 19.83  ? 153 TYR A CE2 1 
ATOM   1183  C CZ  . TYR A 1 152 ? 153.279 155.156 124.205 1.00 19.30  ? 153 TYR A CZ  1 
ATOM   1184  O OH  . TYR A 1 152 ? 153.301 156.527 124.242 1.00 21.34  ? 153 TYR A OH  1 
ATOM   1185  N N   . VAL A 1 153 ? 155.035 148.353 124.264 1.00 17.59  ? 154 VAL A N   1 
ATOM   1186  C CA  . VAL A 1 153 ? 155.318 146.967 123.911 1.00 16.36  ? 154 VAL A CA  1 
ATOM   1187  C C   . VAL A 1 153 ? 156.683 146.602 124.477 1.00 18.00  ? 154 VAL A C   1 
ATOM   1188  O O   . VAL A 1 153 ? 157.655 147.341 124.287 1.00 19.35  ? 154 VAL A O   1 
ATOM   1189  C CB  . VAL A 1 153 ? 155.276 146.753 122.386 1.00 15.22  ? 154 VAL A CB  1 
ATOM   1190  C CG1 . VAL A 1 153 ? 155.738 145.355 122.026 1.00 16.31  ? 154 VAL A CG1 1 
ATOM   1191  C CG2 . VAL A 1 153 ? 153.880 147.001 121.858 1.00 17.24  ? 154 VAL A CG2 1 
ATOM   1192  N N   . ASN A 1 154 ? 156.751 145.472 125.178 1.00 16.98  ? 155 ASN A N   1 
ATOM   1193  C CA  . ASN A 1 154 ? 157.998 144.982 125.763 1.00 13.65  ? 155 ASN A CA  1 
ATOM   1194  C C   . ASN A 1 154 ? 158.726 144.157 124.712 1.00 15.10  ? 155 ASN A C   1 
ATOM   1195  O O   . ASN A 1 154 ? 158.409 142.986 124.495 1.00 16.90  ? 155 ASN A O   1 
ATOM   1196  C CB  . ASN A 1 154 ? 157.722 144.164 127.019 1.00 14.58  ? 155 ASN A CB  1 
ATOM   1197  C CG  . ASN A 1 154 ? 158.796 144.334 128.076 1.00 14.64  ? 155 ASN A CG  1 
ATOM   1198  O OD1 . ASN A 1 154 ? 159.973 144.480 127.763 1.00 13.49  ? 155 ASN A OD1 1 
ATOM   1199  N ND2 . ASN A 1 154 ? 158.390 144.317 129.335 1.00 15.65  ? 155 ASN A ND2 1 
ATOM   1200  N N   . ASP A 1 155 ? 159.711 144.770 124.056 1.00 18.27  ? 156 ASP A N   1 
ATOM   1201  C CA  . ASP A 1 155 ? 160.486 144.079 123.035 1.00 16.74  ? 156 ASP A CA  1 
ATOM   1202  C C   . ASP A 1 155 ? 161.597 143.222 123.620 1.00 17.22  ? 156 ASP A C   1 
ATOM   1203  O O   . ASP A 1 155 ? 162.044 142.281 122.959 1.00 18.28  ? 156 ASP A O   1 
ATOM   1204  C CB  . ASP A 1 155 ? 161.084 145.089 122.058 1.00 18.28  ? 156 ASP A CB  1 
ATOM   1205  C CG  . ASP A 1 155 ? 161.858 146.183 122.757 1.00 22.80  ? 156 ASP A CG  1 
ATOM   1206  O OD1 . ASP A 1 155 ? 161.219 147.080 123.343 1.00 20.54  ? 156 ASP A OD1 1 
ATOM   1207  O OD2 . ASP A 1 155 ? 163.105 146.150 122.720 1.00 22.88  ? 156 ASP A OD2 1 
ATOM   1208  N N   . ILE A 1 156 ? 162.059 143.532 124.834 1.00 16.91  ? 157 ILE A N   1 
ATOM   1209  C CA  . ILE A 1 156 ? 163.066 142.698 125.484 1.00 13.29  ? 157 ILE A CA  1 
ATOM   1210  C C   . ILE A 1 156 ? 162.511 141.308 125.749 1.00 13.07  ? 157 ILE A C   1 
ATOM   1211  O O   . ILE A 1 156 ? 163.190 140.299 125.532 1.00 14.44  ? 157 ILE A O   1 
ATOM   1212  C CB  . ILE A 1 156 ? 163.558 143.362 126.782 1.00 12.93  ? 157 ILE A CB  1 
ATOM   1213  C CG1 . ILE A 1 156 ? 163.943 144.817 126.527 1.00 14.49  ? 157 ILE A CG1 1 
ATOM   1214  C CG2 . ILE A 1 156 ? 164.733 142.597 127.358 1.00 10.76  ? 157 ILE A CG2 1 
ATOM   1215  C CD1 . ILE A 1 156 ? 164.617 145.471 127.696 1.00 11.66  ? 157 ILE A CD1 1 
ATOM   1216  N N   . VAL A 1 157 ? 161.268 141.234 126.226 1.00 12.97  ? 158 VAL A N   1 
ATOM   1217  C CA  . VAL A 1 157 ? 160.650 139.944 126.512 1.00 12.94  ? 158 VAL A CA  1 
ATOM   1218  C C   . VAL A 1 157 ? 160.504 139.127 125.235 1.00 13.41  ? 158 VAL A C   1 
ATOM   1219  O O   . VAL A 1 157 ? 160.790 137.926 125.216 1.00 15.79  ? 158 VAL A O   1 
ATOM   1220  C CB  . VAL A 1 157 ? 159.298 140.149 127.220 1.00 13.81  ? 158 VAL A CB  1 
ATOM   1221  C CG1 . VAL A 1 157 ? 158.448 138.896 127.128 1.00 18.83  ? 158 VAL A CG1 1 
ATOM   1222  C CG2 . VAL A 1 157 ? 159.519 140.536 128.669 1.00 10.86  ? 158 VAL A CG2 1 
ATOM   1223  N N   . LEU A 1 158 ? 160.068 139.763 124.147 1.00 13.00  ? 159 LEU A N   1 
ATOM   1224  C CA  . LEU A 1 158 ? 159.904 139.045 122.887 1.00 14.21  ? 159 LEU A CA  1 
ATOM   1225  C C   . LEU A 1 158 ? 161.247 138.605 122.315 1.00 16.07  ? 159 LEU A C   1 
ATOM   1226  O O   . LEU A 1 158 ? 161.358 137.513 121.745 1.00 20.05  ? 159 LEU A O   1 
ATOM   1227  C CB  . LEU A 1 158 ? 159.143 139.917 121.889 1.00 18.39  ? 159 LEU A CB  1 
ATOM   1228  C CG  . LEU A 1 158 ? 157.703 140.251 122.287 1.00 20.47  ? 159 LEU A CG  1 
ATOM   1229  C CD1 . LEU A 1 158 ? 157.199 141.476 121.547 1.00 19.37  ? 159 LEU A CD1 1 
ATOM   1230  C CD2 . LEU A 1 158 ? 156.797 139.065 122.031 1.00 23.09  ? 159 LEU A CD2 1 
ATOM   1231  N N   . ALA A 1 159 ? 162.280 139.440 122.458 1.00 15.92  ? 160 ALA A N   1 
ATOM   1232  C CA  . ALA A 1 159 ? 163.616 139.051 122.020 1.00 13.86  ? 160 ALA A CA  1 
ATOM   1233  C C   . ALA A 1 159 ? 164.135 137.857 122.811 1.00 15.53  ? 160 ALA A C   1 
ATOM   1234  O O   . ALA A 1 159 ? 164.740 136.944 122.240 1.00 19.33  ? 160 ALA A O   1 
ATOM   1235  C CB  . ALA A 1 159 ? 164.574 140.234 122.147 1.00 13.02  ? 160 ALA A CB  1 
ATOM   1236  N N   . ILE A 1 160 ? 163.916 137.848 124.128 1.00 13.69  ? 161 ILE A N   1 
ATOM   1237  C CA  . ILE A 1 160 ? 164.350 136.715 124.942 1.00 14.23  ? 161 ILE A CA  1 
ATOM   1238  C C   . ILE A 1 160 ? 163.559 135.463 124.583 1.00 16.20  ? 161 ILE A C   1 
ATOM   1239  O O   . ILE A 1 160 ? 164.110 134.358 124.538 1.00 17.67  ? 161 ILE A O   1 
ATOM   1240  C CB  . ILE A 1 160 ? 164.236 137.048 126.441 1.00 13.97  ? 161 ILE A CB  1 
ATOM   1241  C CG1 . ILE A 1 160 ? 165.143 138.223 126.802 1.00 12.09  ? 161 ILE A CG1 1 
ATOM   1242  C CG2 . ILE A 1 160 ? 164.608 135.843 127.282 1.00 13.10  ? 161 ILE A CG2 1 
ATOM   1243  C CD1 . ILE A 1 160 ? 164.953 138.724 128.211 1.00 10.28  ? 161 ILE A CD1 1 
ATOM   1244  N N   . LEU A 1 161 ? 162.258 135.612 124.324 1.00 16.23  ? 162 LEU A N   1 
ATOM   1245  C CA  . LEU A 1 161 ? 161.452 134.477 123.888 1.00 16.80  ? 162 LEU A CA  1 
ATOM   1246  C C   . LEU A 1 161 ? 161.938 133.930 122.554 1.00 19.02  ? 162 LEU A C   1 
ATOM   1247  O O   . LEU A 1 161 ? 161.828 132.726 122.300 1.00 22.28  ? 162 LEU A O   1 
ATOM   1248  C CB  . LEU A 1 161 ? 159.981 134.881 123.788 1.00 16.81  ? 162 LEU A CB  1 
ATOM   1249  C CG  . LEU A 1 161 ? 159.205 135.093 125.088 1.00 16.70  ? 162 LEU A CG  1 
ATOM   1250  C CD1 . LEU A 1 161 ? 157.806 135.586 124.781 1.00 15.75  ? 162 LEU A CD1 1 
ATOM   1251  C CD2 . LEU A 1 161 ? 159.158 133.817 125.907 1.00 22.25  ? 162 LEU A CD2 1 
ATOM   1252  N N   . GLU A 1 162 ? 162.461 134.797 121.684 1.00 19.07  ? 163 GLU A N   1 
ATOM   1253  C CA  . GLU A 1 162 ? 163.106 134.323 120.463 1.00 19.66  ? 163 GLU A CA  1 
ATOM   1254  C C   . GLU A 1 162 ? 164.389 133.568 120.788 1.00 20.64  ? 163 GLU A C   1 
ATOM   1255  O O   . GLU A 1 162 ? 164.670 132.522 120.193 1.00 24.75  ? 163 GLU A O   1 
ATOM   1256  C CB  . GLU A 1 162 ? 163.392 135.505 119.533 1.00 19.26  ? 163 GLU A CB  1 
ATOM   1257  C CG  . GLU A 1 162 ? 162.869 135.364 118.101 1.00 24.24  ? 163 GLU A CG  1 
ATOM   1258  C CD  . GLU A 1 162 ? 163.400 134.161 117.342 1.00 35.73  ? 163 GLU A CD  1 
ATOM   1259  O OE1 . GLU A 1 162 ? 164.414 133.567 117.762 1.00 34.03  ? 163 GLU A OE1 1 
ATOM   1260  O OE2 . GLU A 1 162 ? 162.785 133.792 116.321 1.00 44.60  ? 163 GLU A OE2 1 
ATOM   1261  N N   . LEU A 1 163 ? 165.173 134.075 121.742 1.00 20.70  ? 164 LEU A N   1 
ATOM   1262  C CA  . LEU A 1 163 ? 166.420 133.414 122.110 1.00 19.06  ? 164 LEU A CA  1 
ATOM   1263  C C   . LEU A 1 163 ? 166.174 132.081 122.801 1.00 21.69  ? 164 LEU A C   1 
ATOM   1264  O O   . LEU A 1 163 ? 166.970 131.149 122.643 1.00 25.68  ? 164 LEU A O   1 
ATOM   1265  C CB  . LEU A 1 163 ? 167.255 134.324 123.011 1.00 18.09  ? 164 LEU A CB  1 
ATOM   1266  C CG  . LEU A 1 163 ? 167.976 135.503 122.357 1.00 17.13  ? 164 LEU A CG  1 
ATOM   1267  C CD1 . LEU A 1 163 ? 168.464 136.470 123.414 1.00 14.13  ? 164 LEU A CD1 1 
ATOM   1268  C CD2 . LEU A 1 163 ? 169.129 135.021 121.499 1.00 17.34  ? 164 LEU A CD2 1 
ATOM   1269  N N   . LEU A 1 164 ? 165.086 131.967 123.567 1.00 21.33  ? 165 LEU A N   1 
ATOM   1270  C CA  . LEU A 1 164 ? 164.812 130.742 124.311 1.00 21.12  ? 165 LEU A CA  1 
ATOM   1271  C C   . LEU A 1 164 ? 164.512 129.558 123.401 1.00 25.85  ? 165 LEU A C   1 
ATOM   1272  O O   . LEU A 1 164 ? 164.543 128.414 123.867 1.00 29.43  ? 165 LEU A O   1 
ATOM   1273  C CB  . LEU A 1 164 ? 163.647 130.962 125.277 1.00 20.35  ? 165 LEU A CB  1 
ATOM   1274  C CG  . LEU A 1 164 ? 163.964 131.673 126.593 1.00 19.71  ? 165 LEU A CG  1 
ATOM   1275  C CD1 . LEU A 1 164 ? 162.732 131.746 127.472 1.00 18.72  ? 165 LEU A CD1 1 
ATOM   1276  C CD2 . LEU A 1 164 ? 165.101 130.983 127.320 1.00 18.59  ? 165 LEU A CD2 1 
ATOM   1277  N N   . LYS A 1 165 ? 164.220 129.801 122.123 1.00 27.77  ? 166 LYS A N   1 
ATOM   1278  C CA  . LYS A 1 165 ? 164.023 128.709 121.178 1.00 31.28  ? 166 LYS A CA  1 
ATOM   1279  C C   . LYS A 1 165 ? 165.298 127.917 120.935 1.00 34.28  ? 166 LYS A C   1 
ATOM   1280  O O   . LYS A 1 165 ? 165.227 126.780 120.458 1.00 43.25  ? 166 LYS A O   1 
ATOM   1281  C CB  . LYS A 1 165 ? 163.508 129.248 119.844 1.00 29.79  ? 166 LYS A CB  1 
ATOM   1282  C CG  . LYS A 1 165 ? 162.097 129.790 119.877 1.00 31.73  ? 166 LYS A CG  1 
ATOM   1283  C CD  . LYS A 1 165 ? 161.711 130.356 118.522 1.00 32.61  ? 166 LYS A CD  1 
ATOM   1284  C CE  . LYS A 1 165 ? 160.401 131.118 118.590 1.00 39.59  ? 166 LYS A CE  1 
ATOM   1285  N NZ  . LYS A 1 165 ? 160.267 132.081 117.464 1.00 41.19  ? 166 LYS A NZ  1 
ATOM   1286  N N   . TYR A 1 166 ? 166.460 128.493 121.246 1.00 32.18  ? 167 TYR A N   1 
ATOM   1287  C CA  . TYR A 1 166 ? 167.742 127.909 120.892 1.00 34.63  ? 167 TYR A CA  1 
ATOM   1288  C C   . TYR A 1 166 ? 168.682 127.739 122.072 1.00 33.46  ? 167 TYR A C   1 
ATOM   1289  O O   . TYR A 1 166 ? 169.580 126.894 122.004 1.00 34.88  ? 167 TYR A O   1 
ATOM   1290  C CB  . TYR A 1 166 ? 168.441 128.782 119.840 1.00 34.50  ? 167 TYR A CB  1 
ATOM   1291  C CG  . TYR A 1 166 ? 167.974 128.538 118.428 1.00 39.30  ? 167 TYR A CG  1 
ATOM   1292  C CD1 . TYR A 1 166 ? 166.672 128.835 118.053 1.00 39.05  ? 167 TYR A CD1 1 
ATOM   1293  C CD2 . TYR A 1 166 ? 168.825 128.017 117.471 1.00 43.81  ? 167 TYR A CD2 1 
ATOM   1294  C CE1 . TYR A 1 166 ? 166.232 128.621 116.769 1.00 45.67  ? 167 TYR A CE1 1 
ATOM   1295  C CE2 . TYR A 1 166 ? 168.393 127.804 116.179 1.00 56.93  ? 167 TYR A CE2 1 
ATOM   1296  C CZ  . TYR A 1 166 ? 167.095 128.106 115.836 1.00 58.50  ? 167 TYR A CZ  1 
ATOM   1297  O OH  . TYR A 1 166 ? 166.655 127.895 114.553 1.00 66.46  ? 167 TYR A OH  1 
ATOM   1298  N N   . HIS A 1 167 ? 168.507 128.515 123.139 1.00 30.54  ? 168 HIS A N   1 
ATOM   1299  C CA  . HIS A 1 167 ? 169.404 128.518 124.285 1.00 26.58  ? 168 HIS A CA  1 
ATOM   1300  C C   . HIS A 1 167 ? 168.637 128.071 125.519 1.00 26.76  ? 168 HIS A C   1 
ATOM   1301  O O   . HIS A 1 167 ? 167.525 128.545 125.769 1.00 24.59  ? 168 HIS A O   1 
ATOM   1302  C CB  . HIS A 1 167 ? 170.004 129.910 124.501 1.00 21.96  ? 168 HIS A CB  1 
ATOM   1303  C CG  . HIS A 1 167 ? 170.713 130.454 123.300 1.00 25.41  ? 168 HIS A CG  1 
ATOM   1304  N ND1 . HIS A 1 167 ? 171.983 130.058 122.941 1.00 24.73  ? 168 HIS A ND1 1 
ATOM   1305  C CD2 . HIS A 1 167 ? 170.327 131.361 122.372 1.00 25.19  ? 168 HIS A CD2 1 
ATOM   1306  C CE1 . HIS A 1 167 ? 172.349 130.697 121.845 1.00 21.47  ? 168 HIS A CE1 1 
ATOM   1307  N NE2 . HIS A 1 167 ? 171.362 131.495 121.480 1.00 20.57  ? 168 HIS A NE2 1 
ATOM   1308  N N   . GLN A 1 168 ? 169.230 127.153 126.283 1.00 31.67  ? 169 GLN A N   1 
ATOM   1309  C CA  . GLN A 1 168 ? 168.565 126.643 127.477 1.00 32.21  ? 169 GLN A CA  1 
ATOM   1310  C C   . GLN A 1 168 ? 168.440 127.717 128.550 1.00 28.03  ? 169 GLN A C   1 
ATOM   1311  O O   . GLN A 1 168 ? 167.403 127.818 129.213 1.00 29.11  ? 169 GLN A O   1 
ATOM   1312  C CB  . GLN A 1 168 ? 169.320 125.431 128.018 1.00 39.62  ? 169 GLN A CB  1 
ATOM   1313  C CG  . GLN A 1 168 ? 168.485 124.530 128.908 1.00 45.78  ? 169 GLN A CG  1 
ATOM   1314  C CD  . GLN A 1 168 ? 169.317 123.479 129.611 1.00 53.42  ? 169 GLN A CD  1 
ATOM   1315  O OE1 . GLN A 1 168 ? 169.155 123.239 130.808 1.00 56.99  ? 169 GLN A OE1 1 
ATOM   1316  N NE2 . GLN A 1 168 ? 170.220 122.847 128.870 1.00 50.54  ? 169 GLN A NE2 1 
ATOM   1317  N N   . ARG A 1 169 ? 169.482 128.524 128.739 1.00 26.06  ? 170 ARG A N   1 
ATOM   1318  C CA  . ARG A 1 169 ? 169.508 129.541 129.782 1.00 19.79  ? 170 ARG A CA  1 
ATOM   1319  C C   . ARG A 1 169 ? 169.945 130.872 129.189 1.00 18.70  ? 170 ARG A C   1 
ATOM   1320  O O   . ARG A 1 169 ? 170.927 130.930 128.444 1.00 16.82  ? 170 ARG A O   1 
ATOM   1321  C CB  . ARG A 1 169 ? 170.445 129.131 130.920 1.00 23.54  ? 170 ARG A CB  1 
ATOM   1322  C CG  . ARG A 1 169 ? 169.906 128.005 131.786 1.00 28.37  ? 170 ARG A CG  1 
ATOM   1323  C CD  . ARG A 1 169 ? 170.945 127.524 132.778 1.00 27.18  ? 170 ARG A CD  1 
ATOM   1324  N NE  . ARG A 1 169 ? 172.152 127.057 132.108 1.00 29.40  ? 170 ARG A NE  1 
ATOM   1325  C CZ  . ARG A 1 169 ? 172.328 125.822 131.659 1.00 37.15  ? 170 ARG A CZ  1 
ATOM   1326  N NH1 . ARG A 1 169 ? 171.393 124.897 131.796 1.00 36.47  ? 170 ARG A NH1 1 
ATOM   1327  N NH2 . ARG A 1 169 ? 173.471 125.508 131.056 1.00 38.70  ? 170 ARG A NH2 1 
ATOM   1328  N N   . VAL A 1 170 ? 169.217 131.934 129.525 1.00 18.01  ? 171 VAL A N   1 
ATOM   1329  C CA  . VAL A 1 170 ? 169.496 133.285 129.051 1.00 13.78  ? 171 VAL A CA  1 
ATOM   1330  C C   . VAL A 1 170 ? 169.639 134.195 130.262 1.00 12.70  ? 171 VAL A C   1 
ATOM   1331  O O   . VAL A 1 170 ? 168.828 134.129 131.191 1.00 15.19  ? 171 VAL A O   1 
ATOM   1332  C CB  . VAL A 1 170 ? 168.389 133.797 128.110 1.00 13.23  ? 171 VAL A CB  1 
ATOM   1333  C CG1 . VAL A 1 170 ? 168.670 135.227 127.679 1.00 12.17  ? 171 VAL A CG1 1 
ATOM   1334  C CG2 . VAL A 1 170 ? 168.259 132.892 126.896 1.00 15.02  ? 171 VAL A CG2 1 
ATOM   1335  N N   . LEU A 1 171 ? 170.670 135.034 130.257 1.00 11.74  ? 172 LEU A N   1 
ATOM   1336  C CA  . LEU A 1 171 ? 170.916 135.988 131.331 1.00 11.50  ? 172 LEU A CA  1 
ATOM   1337  C C   . LEU A 1 171 ? 170.579 137.393 130.855 1.00 11.53  ? 172 LEU A C   1 
ATOM   1338  O O   . LEU A 1 171 ? 171.040 137.820 129.793 1.00 11.44  ? 172 LEU A O   1 
ATOM   1339  C CB  . LEU A 1 171 ? 172.369 135.929 131.801 1.00 10.80  ? 172 LEU A CB  1 
ATOM   1340  C CG  . LEU A 1 171 ? 172.741 136.930 132.895 1.00 9.66   ? 172 LEU A CG  1 
ATOM   1341  C CD1 . LEU A 1 171 ? 171.986 136.635 134.174 1.00 10.30  ? 172 LEU A CD1 1 
ATOM   1342  C CD2 . LEU A 1 171 ? 174.228 136.919 133.150 1.00 9.04   ? 172 LEU A CD2 1 
ATOM   1343  N N   . TYR A 1 172 ? 169.780 138.107 131.642 1.00 10.59  ? 173 TYR A N   1 
ATOM   1344  C CA  . TYR A 1 172 ? 169.382 139.476 131.341 1.00 8.63   ? 173 TYR A CA  1 
ATOM   1345  C C   . TYR A 1 172 ? 169.969 140.401 132.397 1.00 8.18   ? 173 TYR A C   1 
ATOM   1346  O O   . TYR A 1 172 ? 169.749 140.198 133.594 1.00 10.12  ? 173 TYR A O   1 
ATOM   1347  C CB  . TYR A 1 172 ? 167.858 139.600 131.293 1.00 9.13   ? 173 TYR A CB  1 
ATOM   1348  C CG  . TYR A 1 172 ? 167.354 141.025 131.288 1.00 10.18  ? 173 TYR A CG  1 
ATOM   1349  C CD1 . TYR A 1 172 ? 167.503 141.831 130.169 1.00 7.98   ? 173 TYR A CD1 1 
ATOM   1350  C CD2 . TYR A 1 172 ? 166.728 141.563 132.402 1.00 10.69  ? 173 TYR A CD2 1 
ATOM   1351  C CE1 . TYR A 1 172 ? 167.050 143.131 130.161 1.00 7.28   ? 173 TYR A CE1 1 
ATOM   1352  C CE2 . TYR A 1 172 ? 166.270 142.862 132.402 1.00 10.81  ? 173 TYR A CE2 1 
ATOM   1353  C CZ  . TYR A 1 172 ? 166.432 143.640 131.279 1.00 9.88   ? 173 TYR A CZ  1 
ATOM   1354  O OH  . TYR A 1 172 ? 165.975 144.935 131.276 1.00 11.62  ? 173 TYR A OH  1 
ATOM   1355  N N   . ILE A 1 173 ? 170.713 141.412 131.954 1.00 8.81   ? 174 ILE A N   1 
ATOM   1356  C CA  . ILE A 1 173 ? 171.327 142.398 132.836 1.00 8.14   ? 174 ILE A CA  1 
ATOM   1357  C C   . ILE A 1 173 ? 170.760 143.766 132.492 1.00 9.29   ? 174 ILE A C   1 
ATOM   1358  O O   . ILE A 1 173 ? 170.623 144.108 131.313 1.00 10.00  ? 174 ILE A O   1 
ATOM   1359  C CB  . ILE A 1 173 ? 172.862 142.401 132.720 1.00 8.03   ? 174 ILE A CB  1 
ATOM   1360  C CG1 . ILE A 1 173 ? 173.405 140.974 132.714 1.00 7.39   ? 174 ILE A CG1 1 
ATOM   1361  C CG2 . ILE A 1 173 ? 173.479 143.192 133.859 1.00 7.57   ? 174 ILE A CG2 1 
ATOM   1362  C CD1 . ILE A 1 173 ? 174.787 140.859 132.138 1.00 7.06   ? 174 ILE A CD1 1 
ATOM   1363  N N   . ASP A 1 174 ? 170.432 144.543 133.520 1.00 9.50   ? 175 ASP A N   1 
ATOM   1364  C CA  . ASP A 1 174 ? 169.788 145.841 133.361 1.00 9.54   ? 175 ASP A CA  1 
ATOM   1365  C C   . ASP A 1 174 ? 170.559 146.872 134.170 1.00 10.70  ? 175 ASP A C   1 
ATOM   1366  O O   . ASP A 1 174 ? 170.631 146.769 135.397 1.00 11.60  ? 175 ASP A O   1 
ATOM   1367  C CB  . ASP A 1 174 ? 168.326 145.768 133.811 1.00 11.54  ? 175 ASP A CB  1 
ATOM   1368  C CG  . ASP A 1 174 ? 167.636 147.111 133.794 1.00 15.46  ? 175 ASP A CG  1 
ATOM   1369  O OD1 . ASP A 1 174 ? 167.748 147.856 134.792 1.00 16.74  ? 175 ASP A OD1 1 
ATOM   1370  O OD2 . ASP A 1 174 ? 166.969 147.418 132.787 1.00 13.35  ? 175 ASP A OD2 1 
ATOM   1371  N N   . ILE A 1 175 ? 171.138 147.857 133.487 1.00 10.41  ? 176 ILE A N   1 
ATOM   1372  C CA  . ILE A 1 175 ? 171.889 148.921 134.142 1.00 11.12  ? 176 ILE A CA  1 
ATOM   1373  C C   . ILE A 1 175 ? 171.179 150.268 134.007 1.00 12.86  ? 176 ILE A C   1 
ATOM   1374  O O   . ILE A 1 175 ? 171.792 151.313 134.197 1.00 13.18  ? 176 ILE A O   1 
ATOM   1375  C CB  . ILE A 1 175 ? 173.336 148.995 133.626 1.00 12.61  ? 176 ILE A CB  1 
ATOM   1376  C CG1 . ILE A 1 175 ? 173.365 149.337 132.136 1.00 12.15  ? 176 ILE A CG1 1 
ATOM   1377  C CG2 . ILE A 1 175 ? 174.067 147.693 133.907 1.00 11.35  ? 176 ILE A CG2 1 
ATOM   1378  C CD1 . ILE A 1 175 ? 174.746 149.605 131.599 1.00 11.50  ? 176 ILE A CD1 1 
ATOM   1379  N N   . ASP A 1 176 ? 169.892 150.251 133.676 1.00 15.70  ? 177 ASP A N   1 
ATOM   1380  C CA  . ASP A 1 176 ? 169.062 151.438 133.806 1.00 12.53  ? 177 ASP A CA  1 
ATOM   1381  C C   . ASP A 1 176 ? 168.932 151.816 135.277 1.00 12.66  ? 177 ASP A C   1 
ATOM   1382  O O   . ASP A 1 176 ? 169.000 150.964 136.165 1.00 14.94  ? 177 ASP A O   1 
ATOM   1383  C CB  . ASP A 1 176 ? 167.681 151.176 133.203 1.00 12.27  ? 177 ASP A CB  1 
ATOM   1384  C CG  . ASP A 1 176 ? 167.009 152.432 132.701 1.00 16.81  ? 177 ASP A CG  1 
ATOM   1385  O OD1 . ASP A 1 176 ? 167.238 152.799 131.534 1.00 21.94  ? 177 ASP A OD1 1 
ATOM   1386  O OD2 . ASP A 1 176 ? 166.230 153.041 133.462 1.00 14.04  ? 177 ASP A OD2 1 
ATOM   1387  N N   . ILE A 1 177 ? 168.749 153.113 135.539 1.00 10.87  ? 178 ILE A N   1 
ATOM   1388  C CA  . ILE A 1 177 ? 168.602 153.567 136.917 1.00 8.73   ? 178 ILE A CA  1 
ATOM   1389  C C   . ILE A 1 177 ? 167.290 153.089 137.528 1.00 9.57   ? 178 ILE A C   1 
ATOM   1390  O O   . ILE A 1 177 ? 167.137 153.113 138.753 1.00 10.85  ? 178 ILE A O   1 
ATOM   1391  C CB  . ILE A 1 177 ? 168.726 155.102 136.994 1.00 11.59  ? 178 ILE A CB  1 
ATOM   1392  C CG1 . ILE A 1 177 ? 169.048 155.550 138.420 1.00 14.37  ? 178 ILE A CG1 1 
ATOM   1393  C CG2 . ILE A 1 177 ? 167.461 155.775 136.517 1.00 12.08  ? 178 ILE A CG2 1 
ATOM   1394  C CD1 . ILE A 1 177 ? 169.188 157.040 138.576 1.00 12.56  ? 178 ILE A CD1 1 
ATOM   1395  N N   . HIS A 1 178 ? 166.346 152.640 136.710 1.00 12.26  ? 179 HIS A N   1 
ATOM   1396  C CA  . HIS A 1 178 ? 165.061 152.140 137.171 1.00 9.01   ? 179 HIS A CA  1 
ATOM   1397  C C   . HIS A 1 178 ? 165.031 150.617 137.131 1.00 11.32  ? 179 HIS A C   1 
ATOM   1398  O O   . HIS A 1 178 ? 165.797 149.974 136.411 1.00 16.58  ? 179 HIS A O   1 
ATOM   1399  C CB  . HIS A 1 178 ? 163.920 152.705 136.322 1.00 9.42   ? 179 HIS A CB  1 
ATOM   1400  C CG  . HIS A 1 178 ? 163.804 154.196 136.380 1.00 12.13  ? 179 HIS A CG  1 
ATOM   1401  N ND1 . HIS A 1 178 ? 164.402 155.026 135.457 1.00 12.31  ? 179 HIS A ND1 1 
ATOM   1402  C CD2 . HIS A 1 178 ? 163.164 155.006 137.254 1.00 12.19  ? 179 HIS A CD2 1 
ATOM   1403  C CE1 . HIS A 1 178 ? 164.135 156.283 135.760 1.00 12.31  ? 179 HIS A CE1 1 
ATOM   1404  N NE2 . HIS A 1 178 ? 163.386 156.298 136.846 1.00 12.32  ? 179 HIS A NE2 1 
ATOM   1405  N N   . HIS A 1 179 ? 164.131 150.047 137.925 1.00 11.34  ? 180 HIS A N   1 
ATOM   1406  C CA  . HIS A 1 179 ? 163.980 148.600 137.980 1.00 10.72  ? 180 HIS A CA  1 
ATOM   1407  C C   . HIS A 1 179 ? 163.345 148.075 136.699 1.00 12.39  ? 180 HIS A C   1 
ATOM   1408  O O   . HIS A 1 179 ? 162.374 148.638 136.190 1.00 14.58  ? 180 HIS A O   1 
ATOM   1409  C CB  . HIS A 1 179 ? 163.131 148.204 139.189 1.00 11.98  ? 180 HIS A CB  1 
ATOM   1410  C CG  . HIS A 1 179 ? 162.961 146.727 139.353 1.00 12.38  ? 180 HIS A CG  1 
ATOM   1411  N ND1 . HIS A 1 179 ? 161.725 146.126 139.440 1.00 12.95  ? 180 HIS A ND1 1 
ATOM   1412  C CD2 . HIS A 1 179 ? 163.870 145.729 139.441 1.00 13.15  ? 180 HIS A CD2 1 
ATOM   1413  C CE1 . HIS A 1 179 ? 161.880 144.822 139.575 1.00 14.06  ? 180 HIS A CE1 1 
ATOM   1414  N NE2 . HIS A 1 179 ? 163.172 144.555 139.578 1.00 13.95  ? 180 HIS A NE2 1 
ATOM   1415  N N   . GLY A 1 180 ? 163.902 146.988 136.175 1.00 11.61  ? 181 GLY A N   1 
ATOM   1416  C CA  . GLY A 1 180 ? 163.323 146.335 135.019 1.00 11.08  ? 181 GLY A CA  1 
ATOM   1417  C C   . GLY A 1 180 ? 162.145 145.469 135.405 1.00 14.69  ? 181 GLY A C   1 
ATOM   1418  O O   . GLY A 1 180 ? 162.239 144.239 135.396 1.00 15.86  ? 181 GLY A O   1 
ATOM   1419  N N   . ASP A 1 181 ? 161.026 146.110 135.755 1.00 15.68  ? 182 ASP A N   1 
ATOM   1420  C CA  . ASP A 1 181 ? 159.893 145.385 136.318 1.00 15.47  ? 182 ASP A CA  1 
ATOM   1421  C C   . ASP A 1 181 ? 159.122 144.615 135.256 1.00 19.15  ? 182 ASP A C   1 
ATOM   1422  O O   . ASP A 1 181 ? 158.568 143.550 135.549 1.00 21.78  ? 182 ASP A O   1 
ATOM   1423  C CB  . ASP A 1 181 ? 158.963 146.355 137.044 1.00 15.32  ? 182 ASP A CB  1 
ATOM   1424  C CG  . ASP A 1 181 ? 158.680 147.601 136.235 1.00 20.15  ? 182 ASP A CG  1 
ATOM   1425  O OD1 . ASP A 1 181 ? 159.610 148.098 135.570 1.00 19.00  ? 182 ASP A OD1 1 
ATOM   1426  O OD2 . ASP A 1 181 ? 157.529 148.084 136.260 1.00 22.88  ? 182 ASP A OD2 1 
ATOM   1427  N N   . GLY A 1 182 ? 159.060 145.136 134.031 1.00 18.24  ? 183 GLY A N   1 
ATOM   1428  C CA  . GLY A 1 182 ? 158.335 144.440 132.982 1.00 16.60  ? 183 GLY A CA  1 
ATOM   1429  C C   . GLY A 1 182 ? 158.982 143.125 132.597 1.00 14.88  ? 183 GLY A C   1 
ATOM   1430  O O   . GLY A 1 182 ? 158.291 142.158 132.265 1.00 14.98  ? 183 GLY A O   1 
ATOM   1431  N N   . VAL A 1 183 ? 160.314 143.071 132.627 1.00 15.94  ? 184 VAL A N   1 
ATOM   1432  C CA  . VAL A 1 183 ? 161.023 141.853 132.248 1.00 15.72  ? 184 VAL A CA  1 
ATOM   1433  C C   . VAL A 1 183 ? 161.082 140.875 133.413 1.00 15.00  ? 184 VAL A C   1 
ATOM   1434  O O   . VAL A 1 183 ? 160.984 139.659 133.220 1.00 16.24  ? 184 VAL A O   1 
ATOM   1435  C CB  . VAL A 1 183 ? 162.430 142.198 131.728 1.00 12.43  ? 184 VAL A CB  1 
ATOM   1436  C CG1 . VAL A 1 183 ? 162.960 141.078 130.850 1.00 11.86  ? 184 VAL A CG1 1 
ATOM   1437  C CG2 . VAL A 1 183 ? 162.405 143.503 130.967 1.00 11.93  ? 184 VAL A CG2 1 
ATOM   1438  N N   . GLU A 1 184 ? 161.251 141.382 134.635 1.00 17.91  ? 185 GLU A N   1 
ATOM   1439  C CA  . GLU A 1 184 ? 161.293 140.502 135.797 1.00 18.30  ? 185 GLU A CA  1 
ATOM   1440  C C   . GLU A 1 184 ? 159.943 139.843 136.044 1.00 21.79  ? 185 GLU A C   1 
ATOM   1441  O O   . GLU A 1 184 ? 159.882 138.672 136.431 1.00 25.76  ? 185 GLU A O   1 
ATOM   1442  C CB  . GLU A 1 184 ? 161.744 141.281 137.031 1.00 19.52  ? 185 GLU A CB  1 
ATOM   1443  C CG  . GLU A 1 184 ? 161.744 140.457 138.305 1.00 26.67  ? 185 GLU A CG  1 
ATOM   1444  C CD  . GLU A 1 184 ? 162.679 141.007 139.359 1.00 30.64  ? 185 GLU A CD  1 
ATOM   1445  O OE1 . GLU A 1 184 ? 163.891 141.120 139.077 1.00 30.16  ? 185 GLU A OE1 1 
ATOM   1446  O OE2 . GLU A 1 184 ? 162.206 141.313 140.472 1.00 27.19  ? 185 GLU A OE2 1 
ATOM   1447  N N   . GLU A 1 185 ? 158.851 140.579 135.831 1.00 20.47  ? 186 GLU A N   1 
ATOM   1448  C CA  . GLU A 1 185 ? 157.522 140.014 136.041 1.00 21.02  ? 186 GLU A CA  1 
ATOM   1449  C C   . GLU A 1 185 ? 157.220 138.903 135.042 1.00 21.38  ? 186 GLU A C   1 
ATOM   1450  O O   . GLU A 1 185 ? 156.627 137.882 135.405 1.00 28.59  ? 186 GLU A O   1 
ATOM   1451  C CB  . GLU A 1 185 ? 156.465 141.112 135.951 1.00 22.44  ? 186 GLU A CB  1 
ATOM   1452  C CG  . GLU A 1 185 ? 155.059 140.639 136.267 1.00 33.64  ? 186 GLU A CG  1 
ATOM   1453  C CD  . GLU A 1 185 ? 153.999 141.630 135.836 1.00 39.69  ? 186 GLU A CD  1 
ATOM   1454  O OE1 . GLU A 1 185 ? 153.747 141.742 134.618 1.00 37.61  ? 186 GLU A OE1 1 
ATOM   1455  O OE2 . GLU A 1 185 ? 153.415 142.296 136.715 1.00 41.90  ? 186 GLU A OE2 1 
ATOM   1456  N N   . ALA A 1 186 ? 157.615 139.085 133.781 1.00 21.15  ? 187 ALA A N   1 
ATOM   1457  C CA  . ALA A 1 186 ? 157.307 138.097 132.752 1.00 18.64  ? 187 ALA A CA  1 
ATOM   1458  C C   . ALA A 1 186 ? 158.012 136.774 133.017 1.00 22.17  ? 187 ALA A C   1 
ATOM   1459  O O   . ALA A 1 186 ? 157.441 135.702 132.789 1.00 26.64  ? 187 ALA A O   1 
ATOM   1460  C CB  . ALA A 1 186 ? 157.690 138.638 131.377 1.00 18.26  ? 187 ALA A CB  1 
ATOM   1461  N N   . PHE A 1 187 ? 159.255 136.826 133.486 1.00 23.48  ? 188 PHE A N   1 
ATOM   1462  C CA  . PHE A 1 187 ? 160.072 135.641 133.723 1.00 21.30  ? 188 PHE A CA  1 
ATOM   1463  C C   . PHE A 1 187 ? 160.320 135.427 135.212 1.00 24.33  ? 188 PHE A C   1 
ATOM   1464  O O   . PHE A 1 187 ? 161.408 135.026 135.627 1.00 27.99  ? 188 PHE A O   1 
ATOM   1465  C CB  . PHE A 1 187 ? 161.396 135.742 132.971 1.00 15.48  ? 188 PHE A CB  1 
ATOM   1466  C CG  . PHE A 1 187 ? 161.239 135.927 131.488 1.00 16.79  ? 188 PHE A CG  1 
ATOM   1467  C CD1 . PHE A 1 187 ? 160.708 134.921 130.703 1.00 17.48  ? 188 PHE A CD1 1 
ATOM   1468  C CD2 . PHE A 1 187 ? 161.624 137.107 130.879 1.00 14.37  ? 188 PHE A CD2 1 
ATOM   1469  C CE1 . PHE A 1 187 ? 160.563 135.091 129.344 1.00 16.42  ? 188 PHE A CE1 1 
ATOM   1470  C CE2 . PHE A 1 187 ? 161.480 137.278 129.520 1.00 12.16  ? 188 PHE A CE2 1 
ATOM   1471  C CZ  . PHE A 1 187 ? 160.950 136.270 128.754 1.00 13.47  ? 188 PHE A CZ  1 
ATOM   1472  N N   . TYR A 1 188 ? 159.305 135.703 136.033 1.00 23.17  ? 189 TYR A N   1 
ATOM   1473  C CA  . TYR A 1 188 ? 159.458 135.609 137.481 1.00 27.58  ? 189 TYR A CA  1 
ATOM   1474  C C   . TYR A 1 188 ? 159.423 134.166 137.967 1.00 28.61  ? 189 TYR A C   1 
ATOM   1475  O O   . TYR A 1 188 ? 160.119 133.818 138.926 1.00 28.06  ? 189 TYR A O   1 
ATOM   1476  C CB  . TYR A 1 188 ? 158.367 136.426 138.173 1.00 27.86  ? 189 TYR A CB  1 
ATOM   1477  C CG  . TYR A 1 188 ? 158.725 136.889 139.565 1.00 30.86  ? 189 TYR A CG  1 
ATOM   1478  C CD1 . TYR A 1 188 ? 159.906 137.572 139.808 1.00 28.34  ? 189 TYR A CD1 1 
ATOM   1479  C CD2 . TYR A 1 188 ? 157.879 136.644 140.637 1.00 35.43  ? 189 TYR A CD2 1 
ATOM   1480  C CE1 . TYR A 1 188 ? 160.236 137.996 141.078 1.00 31.17  ? 189 TYR A CE1 1 
ATOM   1481  C CE2 . TYR A 1 188 ? 158.202 137.064 141.911 1.00 36.60  ? 189 TYR A CE2 1 
ATOM   1482  C CZ  . TYR A 1 188 ? 159.380 137.741 142.125 1.00 35.04  ? 189 TYR A CZ  1 
ATOM   1483  O OH  . TYR A 1 188 ? 159.704 138.162 143.391 1.00 35.72  ? 189 TYR A OH  1 
ATOM   1484  N N   . THR A 1 189 ? 158.623 133.316 137.324 1.00 28.23  ? 190 THR A N   1 
ATOM   1485  C CA  . THR A 1 189 ? 158.404 131.947 137.773 1.00 28.22  ? 190 THR A CA  1 
ATOM   1486  C C   . THR A 1 189 ? 159.063 130.920 136.856 1.00 31.83  ? 190 THR A C   1 
ATOM   1487  O O   . THR A 1 189 ? 158.588 129.789 136.744 1.00 35.59  ? 190 THR A O   1 
ATOM   1488  C CB  . THR A 1 189 ? 156.911 131.655 137.894 1.00 32.89  ? 190 THR A CB  1 
ATOM   1489  O OG1 . THR A 1 189 ? 156.322 131.629 136.589 1.00 38.17  ? 190 THR A OG1 1 
ATOM   1490  C CG2 . THR A 1 189 ? 156.228 132.720 138.725 1.00 33.33  ? 190 THR A CG2 1 
ATOM   1491  N N   . THR A 1 190 ? 160.153 131.298 136.196 1.00 30.20  ? 191 THR A N   1 
ATOM   1492  C CA  . THR A 1 190 ? 160.900 130.385 135.345 1.00 27.91  ? 191 THR A CA  1 
ATOM   1493  C C   . THR A 1 190 ? 162.385 130.501 135.653 1.00 27.14  ? 191 THR A C   1 
ATOM   1494  O O   . THR A 1 190 ? 162.868 131.553 136.079 1.00 31.30  ? 191 THR A O   1 
ATOM   1495  C CB  . THR A 1 190 ? 160.644 130.656 133.852 1.00 28.00  ? 191 THR A CB  1 
ATOM   1496  O OG1 . THR A 1 190 ? 161.234 129.613 133.068 1.00 32.20  ? 191 THR A OG1 1 
ATOM   1497  C CG2 . THR A 1 190 ? 161.232 131.988 133.430 1.00 24.92  ? 191 THR A CG2 1 
ATOM   1498  N N   . ASP A 1 191 ? 163.100 129.397 135.453 1.00 25.48  ? 192 ASP A N   1 
ATOM   1499  C CA  . ASP A 1 191 ? 164.538 129.349 135.668 1.00 23.99  ? 192 ASP A CA  1 
ATOM   1500  C C   . ASP A 1 191 ? 165.329 129.388 134.370 1.00 24.44  ? 192 ASP A C   1 
ATOM   1501  O O   . ASP A 1 191 ? 166.563 129.369 134.411 1.00 25.36  ? 192 ASP A O   1 
ATOM   1502  C CB  . ASP A 1 191 ? 164.910 128.095 136.464 1.00 27.31  ? 192 ASP A CB  1 
ATOM   1503  C CG  . ASP A 1 191 ? 164.526 126.817 135.755 1.00 29.69  ? 192 ASP A CG  1 
ATOM   1504  O OD1 . ASP A 1 191 ? 163.777 126.887 134.762 1.00 32.81  ? 192 ASP A OD1 1 
ATOM   1505  O OD2 . ASP A 1 191 ? 164.971 125.737 136.193 1.00 32.22  ? 192 ASP A OD2 1 
ATOM   1506  N N   . ARG A 1 192 ? 164.652 129.437 133.223 1.00 24.13  ? 193 ARG A N   1 
ATOM   1507  C CA  . ARG A 1 192 ? 165.348 129.536 131.948 1.00 20.11  ? 193 ARG A CA  1 
ATOM   1508  C C   . ARG A 1 192 ? 165.885 130.936 131.696 1.00 18.53  ? 193 ARG A C   1 
ATOM   1509  O O   . ARG A 1 192 ? 166.748 131.107 130.829 1.00 19.80  ? 193 ARG A O   1 
ATOM   1510  C CB  . ARG A 1 192 ? 164.419 129.119 130.810 1.00 21.34  ? 193 ARG A CB  1 
ATOM   1511  C CG  . ARG A 1 192 ? 163.951 127.681 130.891 1.00 20.88  ? 193 ARG A CG  1 
ATOM   1512  C CD  . ARG A 1 192 ? 163.172 127.288 129.651 1.00 26.86  ? 193 ARG A CD  1 
ATOM   1513  N NE  . ARG A 1 192 ? 164.037 127.119 128.491 1.00 26.69  ? 193 ARG A NE  1 
ATOM   1514  C CZ  . ARG A 1 192 ? 163.611 127.095 127.237 1.00 30.90  ? 193 ARG A CZ  1 
ATOM   1515  N NH1 . ARG A 1 192 ? 162.330 127.227 126.942 1.00 36.78  ? 193 ARG A NH1 1 
ATOM   1516  N NH2 . ARG A 1 192 ? 164.491 126.934 126.255 1.00 32.16  ? 193 ARG A NH2 1 
ATOM   1517  N N   . VAL A 1 193 ? 165.393 131.937 132.422 1.00 16.53  ? 194 VAL A N   1 
ATOM   1518  C CA  . VAL A 1 193 ? 165.894 133.303 132.340 1.00 14.42  ? 194 VAL A CA  1 
ATOM   1519  C C   . VAL A 1 193 ? 166.192 133.787 133.751 1.00 15.95  ? 194 VAL A C   1 
ATOM   1520  O O   . VAL A 1 193 ? 165.333 133.700 134.635 1.00 17.21  ? 194 VAL A O   1 
ATOM   1521  C CB  . VAL A 1 193 ? 164.892 134.248 131.647 1.00 12.90  ? 194 VAL A CB  1 
ATOM   1522  C CG1 . VAL A 1 193 ? 165.496 135.632 131.476 1.00 11.06  ? 194 VAL A CG1 1 
ATOM   1523  C CG2 . VAL A 1 193 ? 164.466 133.686 130.304 1.00 15.52  ? 194 VAL A CG2 1 
ATOM   1524  N N   . MET A 1 194 ? 167.405 134.290 133.963 1.00 15.24  ? 195 MET A N   1 
ATOM   1525  C CA  . MET A 1 194 ? 167.790 134.939 135.209 1.00 13.36  ? 195 MET A CA  1 
ATOM   1526  C C   . MET A 1 194 ? 167.907 136.433 134.952 1.00 13.74  ? 195 MET A C   1 
ATOM   1527  O O   . MET A 1 194 ? 168.674 136.856 134.082 1.00 14.68  ? 195 MET A O   1 
ATOM   1528  C CB  . MET A 1 194 ? 169.107 134.385 135.745 1.00 16.92  ? 195 MET A CB  1 
ATOM   1529  C CG  . MET A 1 194 ? 169.685 135.199 136.886 1.00 17.14  ? 195 MET A CG  1 
ATOM   1530  S SD  . MET A 1 194 ? 171.075 134.400 137.698 1.00 27.22  ? 195 MET A SD  1 
ATOM   1531  C CE  . MET A 1 194 ? 170.220 133.183 138.684 1.00 22.23  ? 195 MET A CE  1 
ATOM   1532  N N   . THR A 1 195 ? 167.155 137.225 135.708 1.00 13.26  ? 196 THR A N   1 
ATOM   1533  C CA  . THR A 1 195 ? 167.068 138.666 135.505 1.00 11.98  ? 196 THR A CA  1 
ATOM   1534  C C   . THR A 1 195 ? 167.836 139.367 136.617 1.00 10.93  ? 196 THR A C   1 
ATOM   1535  O O   . THR A 1 195 ? 167.435 139.314 137.783 1.00 14.03  ? 196 THR A O   1 
ATOM   1536  C CB  . THR A 1 195 ? 165.611 139.121 135.468 1.00 14.09  ? 196 THR A CB  1 
ATOM   1537  O OG1 . THR A 1 195 ? 164.926 138.620 136.620 1.00 20.93  ? 196 THR A OG1 1 
ATOM   1538  C CG2 . THR A 1 195 ? 164.922 138.600 134.220 1.00 11.05  ? 196 THR A CG2 1 
ATOM   1539  N N   . VAL A 1 196 ? 168.930 140.029 136.251 1.00 10.57  ? 197 VAL A N   1 
ATOM   1540  C CA  . VAL A 1 196 ? 169.768 140.778 137.181 1.00 10.14  ? 197 VAL A CA  1 
ATOM   1541  C C   . VAL A 1 196 ? 169.531 142.261 136.940 1.00 11.31  ? 197 VAL A C   1 
ATOM   1542  O O   . VAL A 1 196 ? 169.516 142.714 135.790 1.00 12.07  ? 197 VAL A O   1 
ATOM   1543  C CB  . VAL A 1 196 ? 171.254 140.418 137.014 1.00 9.61   ? 197 VAL A CB  1 
ATOM   1544  C CG1 . VAL A 1 196 ? 172.094 141.120 138.065 1.00 9.86   ? 197 VAL A CG1 1 
ATOM   1545  C CG2 . VAL A 1 196 ? 171.440 138.917 137.091 1.00 11.22  ? 197 VAL A CG2 1 
ATOM   1546  N N   . SER A 1 197 ? 169.337 143.015 138.021 1.00 11.27  ? 198 SER A N   1 
ATOM   1547  C CA  . SER A 1 197 ? 168.971 144.421 137.919 1.00 11.00  ? 198 SER A CA  1 
ATOM   1548  C C   . SER A 1 197 ? 169.715 145.234 138.966 1.00 13.74  ? 198 SER A C   1 
ATOM   1549  O O   . SER A 1 197 ? 169.680 144.904 140.154 1.00 14.56  ? 198 SER A O   1 
ATOM   1550  C CB  . SER A 1 197 ? 167.458 144.603 138.089 1.00 11.98  ? 198 SER A CB  1 
ATOM   1551  O OG  . SER A 1 197 ? 167.048 145.904 137.715 1.00 15.70  ? 198 SER A OG  1 
ATOM   1552  N N   . PHE A 1 198 ? 170.388 146.290 138.517 1.00 14.80  ? 199 PHE A N   1 
ATOM   1553  C CA  . PHE A 1 198 ? 170.977 147.301 139.386 1.00 13.71  ? 199 PHE A CA  1 
ATOM   1554  C C   . PHE A 1 198 ? 170.150 148.571 139.239 1.00 17.67  ? 199 PHE A C   1 
ATOM   1555  O O   . PHE A 1 198 ? 169.993 149.083 138.126 1.00 18.45  ? 199 PHE A O   1 
ATOM   1556  C CB  . PHE A 1 198 ? 172.438 147.568 139.022 1.00 12.90  ? 199 PHE A CB  1 
ATOM   1557  C CG  . PHE A 1 198 ? 173.309 146.344 139.034 1.00 13.22  ? 199 PHE A CG  1 
ATOM   1558  C CD1 . PHE A 1 198 ? 173.324 145.473 137.958 1.00 12.39  ? 199 PHE A CD1 1 
ATOM   1559  C CD2 . PHE A 1 198 ? 174.128 146.073 140.115 1.00 17.24  ? 199 PHE A CD2 1 
ATOM   1560  C CE1 . PHE A 1 198 ? 174.126 144.353 137.969 1.00 12.59  ? 199 PHE A CE1 1 
ATOM   1561  C CE2 . PHE A 1 198 ? 174.932 144.954 140.129 1.00 16.11  ? 199 PHE A CE2 1 
ATOM   1562  C CZ  . PHE A 1 198 ? 174.931 144.095 139.056 1.00 14.72  ? 199 PHE A CZ  1 
ATOM   1563  N N   . HIS A 1 199 ? 169.620 149.075 140.350 1.00 14.33  ? 200 HIS A N   1 
ATOM   1564  C CA  . HIS A 1 199 ? 168.659 150.164 140.279 1.00 12.88  ? 200 HIS A CA  1 
ATOM   1565  C C   . HIS A 1 199 ? 168.670 150.954 141.576 1.00 15.79  ? 200 HIS A C   1 
ATOM   1566  O O   . HIS A 1 199 ? 169.151 150.486 142.610 1.00 19.65  ? 200 HIS A O   1 
ATOM   1567  C CB  . HIS A 1 199 ? 167.247 149.636 139.997 1.00 12.29  ? 200 HIS A CB  1 
ATOM   1568  C CG  . HIS A 1 199 ? 166.793 148.583 140.958 1.00 13.57  ? 200 HIS A CG  1 
ATOM   1569  N ND1 . HIS A 1 199 ? 166.959 147.236 140.720 1.00 15.06  ? 200 HIS A ND1 1 
ATOM   1570  C CD2 . HIS A 1 199 ? 166.178 148.678 142.160 1.00 16.73  ? 200 HIS A CD2 1 
ATOM   1571  C CE1 . HIS A 1 199 ? 166.467 146.548 141.734 1.00 15.61  ? 200 HIS A CE1 1 
ATOM   1572  N NE2 . HIS A 1 199 ? 165.987 147.400 142.621 1.00 15.83  ? 200 HIS A NE2 1 
ATOM   1573  N N   . LYS A 1 200 ? 168.126 152.166 141.506 1.00 15.22  ? 201 LYS A N   1 
ATOM   1574  C CA  . LYS A 1 200 ? 167.913 152.981 142.693 1.00 15.84  ? 201 LYS A CA  1 
ATOM   1575  C C   . LYS A 1 200 ? 166.595 152.586 143.347 1.00 17.95  ? 201 LYS A C   1 
ATOM   1576  O O   . LYS A 1 200 ? 165.578 152.428 142.666 1.00 19.78  ? 201 LYS A O   1 
ATOM   1577  C CB  . LYS A 1 200 ? 167.907 154.465 142.327 1.00 13.97  ? 201 LYS A CB  1 
ATOM   1578  C CG  . LYS A 1 200 ? 168.249 155.396 143.473 1.00 15.47  ? 201 LYS A CG  1 
ATOM   1579  C CD  . LYS A 1 200 ? 167.022 156.136 143.957 1.00 15.78  ? 201 LYS A CD  1 
ATOM   1580  C CE  . LYS A 1 200 ? 167.242 156.747 145.322 1.00 17.69  ? 201 LYS A CE  1 
ATOM   1581  N NZ  . LYS A 1 200 ? 165.990 157.332 145.865 1.00 17.83  ? 201 LYS A NZ  1 
ATOM   1582  N N   . TYR A 1 201 ? 166.613 152.423 144.667 1.00 20.24  ? 202 TYR A N   1 
ATOM   1583  C CA  . TYR A 1 201 ? 165.456 151.944 145.405 1.00 20.14  ? 202 TYR A CA  1 
ATOM   1584  C C   . TYR A 1 201 ? 165.125 152.900 146.541 1.00 19.94  ? 202 TYR A C   1 
ATOM   1585  O O   . TYR A 1 201 ? 166.012 153.520 147.133 1.00 20.95  ? 202 TYR A O   1 
ATOM   1586  C CB  . TYR A 1 201 ? 165.698 150.536 145.960 1.00 21.38  ? 202 TYR A CB  1 
ATOM   1587  C CG  . TYR A 1 201 ? 164.475 149.883 146.560 1.00 23.97  ? 202 TYR A CG  1 
ATOM   1588  C CD1 . TYR A 1 201 ? 163.450 149.417 145.754 1.00 22.25  ? 202 TYR A CD1 1 
ATOM   1589  C CD2 . TYR A 1 201 ? 164.346 149.734 147.933 1.00 25.37  ? 202 TYR A CD2 1 
ATOM   1590  C CE1 . TYR A 1 201 ? 162.334 148.824 146.295 1.00 23.16  ? 202 TYR A CE1 1 
ATOM   1591  C CE2 . TYR A 1 201 ? 163.231 149.142 148.482 1.00 26.11  ? 202 TYR A CE2 1 
ATOM   1592  C CZ  . TYR A 1 201 ? 162.229 148.688 147.657 1.00 28.25  ? 202 TYR A CZ  1 
ATOM   1593  O OH  . TYR A 1 201 ? 161.113 148.096 148.198 1.00 37.38  ? 202 TYR A OH  1 
ATOM   1594  N N   . GLY A 1 202 ? 163.833 153.010 146.838 1.00 18.88  ? 203 GLY A N   1 
ATOM   1595  C CA  . GLY A 1 202 ? 163.361 153.828 147.937 1.00 20.95  ? 203 GLY A CA  1 
ATOM   1596  C C   . GLY A 1 202 ? 162.593 155.051 147.487 1.00 25.21  ? 203 GLY A C   1 
ATOM   1597  O O   . GLY A 1 202 ? 163.191 156.074 147.141 1.00 20.71  ? 203 GLY A O   1 
ATOM   1598  N N   . GLU A 1 203 ? 161.263 154.958 147.515 1.00 25.45  ? 204 GLU A N   1 
ATOM   1599  C CA  . GLU A 1 203 ? 160.375 156.022 147.047 1.00 23.14  ? 204 GLU A CA  1 
ATOM   1600  C C   . GLU A 1 203 ? 160.767 156.480 145.645 1.00 22.17  ? 204 GLU A C   1 
ATOM   1601  O O   . GLU A 1 203 ? 160.974 157.665 145.378 1.00 24.60  ? 204 GLU A O   1 
ATOM   1602  C CB  . GLU A 1 203 ? 160.358 157.189 148.033 1.00 26.72  ? 204 GLU A CB  1 
ATOM   1603  C CG  . GLU A 1 203 ? 159.748 156.827 149.372 1.00 27.61  ? 204 GLU A CG  1 
ATOM   1604  C CD  . GLU A 1 203 ? 160.044 157.849 150.443 1.00 34.20  ? 204 GLU A CD  1 
ATOM   1605  O OE1 . GLU A 1 203 ? 160.627 158.900 150.114 1.00 34.00  ? 204 GLU A OE1 1 
ATOM   1606  O OE2 . GLU A 1 203 ? 159.697 157.601 151.616 1.00 35.15  ? 204 GLU A OE2 1 
ATOM   1607  N N   . TYR A 1 204 ? 160.868 155.509 144.741 1.00 19.41  ? 205 TYR A N   1 
ATOM   1608  C CA  . TYR A 1 204 ? 161.346 155.732 143.387 1.00 14.84  ? 205 TYR A CA  1 
ATOM   1609  C C   . TYR A 1 204 ? 160.501 154.912 142.424 1.00 17.31  ? 205 TYR A C   1 
ATOM   1610  O O   . TYR A 1 204 ? 159.891 153.910 142.801 1.00 19.38  ? 205 TYR A O   1 
ATOM   1611  C CB  . TYR A 1 204 ? 162.825 155.349 143.251 1.00 13.66  ? 205 TYR A CB  1 
ATOM   1612  C CG  . TYR A 1 204 ? 163.640 156.257 142.364 1.00 15.36  ? 205 TYR A CG  1 
ATOM   1613  C CD1 . TYR A 1 204 ? 163.800 157.599 142.673 1.00 15.94  ? 205 TYR A CD1 1 
ATOM   1614  C CD2 . TYR A 1 204 ? 164.260 155.769 141.222 1.00 13.65  ? 205 TYR A CD2 1 
ATOM   1615  C CE1 . TYR A 1 204 ? 164.549 158.428 141.868 1.00 14.09  ? 205 TYR A CE1 1 
ATOM   1616  C CE2 . TYR A 1 204 ? 165.010 156.591 140.412 1.00 12.13  ? 205 TYR A CE2 1 
ATOM   1617  C CZ  . TYR A 1 204 ? 165.152 157.919 140.740 1.00 14.83  ? 205 TYR A CZ  1 
ATOM   1618  O OH  . TYR A 1 204 ? 165.898 158.744 139.937 1.00 18.47  ? 205 TYR A OH  1 
ATOM   1619  N N   . PHE A 1 205 ? 160.468 155.355 141.175 1.00 15.39  ? 206 PHE A N   1 
ATOM   1620  C CA  . PHE A 1 205 ? 159.803 154.591 140.133 1.00 13.17  ? 206 PHE A CA  1 
ATOM   1621  C C   . PHE A 1 205 ? 160.580 153.305 139.852 1.00 14.79  ? 206 PHE A C   1 
ATOM   1622  O O   . PHE A 1 205 ? 161.814 153.315 139.844 1.00 14.79  ? 206 PHE A O   1 
ATOM   1623  C CB  . PHE A 1 205 ? 159.689 155.431 138.860 1.00 12.90  ? 206 PHE A CB  1 
ATOM   1624  C CG  . PHE A 1 205 ? 158.800 154.832 137.812 1.00 12.52  ? 206 PHE A CG  1 
ATOM   1625  C CD1 . PHE A 1 205 ? 157.427 154.952 137.899 1.00 12.61  ? 206 PHE A CD1 1 
ATOM   1626  C CD2 . PHE A 1 205 ? 159.339 154.148 136.738 1.00 11.36  ? 206 PHE A CD2 1 
ATOM   1627  C CE1 . PHE A 1 205 ? 156.612 154.400 136.938 1.00 13.39  ? 206 PHE A CE1 1 
ATOM   1628  C CE2 . PHE A 1 205 ? 158.527 153.595 135.777 1.00 10.56  ? 206 PHE A CE2 1 
ATOM   1629  C CZ  . PHE A 1 205 ? 157.164 153.720 135.876 1.00 11.19  ? 206 PHE A CZ  1 
ATOM   1630  N N   . PRO A 1 206 ? 159.892 152.178 139.616 1.00 14.97  ? 207 PRO A N   1 
ATOM   1631  C CA  . PRO A 1 206 ? 158.437 151.978 139.631 1.00 14.74  ? 207 PRO A CA  1 
ATOM   1632  C C   . PRO A 1 206 ? 157.887 151.565 140.990 1.00 17.33  ? 207 PRO A C   1 
ATOM   1633  O O   . PRO A 1 206 ? 156.702 151.281 141.114 1.00 21.59  ? 207 PRO A O   1 
ATOM   1634  C CB  . PRO A 1 206 ? 158.247 150.870 138.594 1.00 11.94  ? 207 PRO A CB  1 
ATOM   1635  C CG  . PRO A 1 206 ? 159.480 150.038 138.732 1.00 12.28  ? 207 PRO A CG  1 
ATOM   1636  C CD  . PRO A 1 206 ? 160.592 150.995 139.086 1.00 12.93  ? 207 PRO A CD  1 
ATOM   1637  N N   . GLY A 1 207 ? 158.714 151.520 142.030 1.00 16.72  ? 208 GLY A N   1 
ATOM   1638  C CA  . GLY A 1 207 ? 158.276 151.094 143.340 1.00 15.55  ? 208 GLY A CA  1 
ATOM   1639  C C   . GLY A 1 207 ? 158.591 149.657 143.688 1.00 20.42  ? 208 GLY A C   1 
ATOM   1640  O O   . GLY A 1 207 ? 158.327 149.243 144.823 1.00 25.16  ? 208 GLY A O   1 
ATOM   1641  N N   . THR A 1 208 ? 159.141 148.887 142.758 1.00 19.61  ? 209 THR A N   1 
ATOM   1642  C CA  . THR A 1 208 ? 159.504 147.496 142.976 1.00 16.68  ? 209 THR A CA  1 
ATOM   1643  C C   . THR A 1 208 ? 161.022 147.349 142.941 1.00 18.43  ? 209 THR A C   1 
ATOM   1644  O O   . THR A 1 208 ? 161.764 148.324 142.790 1.00 19.58  ? 209 THR A O   1 
ATOM   1645  C CB  . THR A 1 208 ? 158.838 146.594 141.933 1.00 16.49  ? 209 THR A CB  1 
ATOM   1646  O OG1 . THR A 1 208 ? 158.938 147.196 140.639 1.00 17.79  ? 209 THR A OG1 1 
ATOM   1647  C CG2 . THR A 1 208 ? 157.374 146.384 142.266 1.00 20.19  ? 209 THR A CG2 1 
ATOM   1648  N N   . GLY A 1 209 ? 161.484 146.111 143.094 1.00 17.55  ? 210 GLY A N   1 
ATOM   1649  C CA  . GLY A 1 209 ? 162.901 145.820 143.023 1.00 18.86  ? 210 GLY A CA  1 
ATOM   1650  C C   . GLY A 1 209 ? 163.552 145.664 144.378 1.00 22.84  ? 210 GLY A C   1 
ATOM   1651  O O   . GLY A 1 209 ? 164.688 146.099 144.588 1.00 24.72  ? 210 GLY A O   1 
ATOM   1652  N N   . ASP A 1 210 ? 162.839 145.037 145.306 1.00 27.97  ? 211 ASP A N   1 
ATOM   1653  C CA  . ASP A 1 210 ? 163.338 144.874 146.662 1.00 30.65  ? 211 ASP A CA  1 
ATOM   1654  C C   . ASP A 1 210 ? 164.437 143.820 146.714 1.00 36.25  ? 211 ASP A C   1 
ATOM   1655  O O   . ASP A 1 210 ? 164.502 142.914 145.880 1.00 35.59  ? 211 ASP A O   1 
ATOM   1656  C CB  . ASP A 1 210 ? 162.193 144.486 147.596 1.00 30.40  ? 211 ASP A CB  1 
ATOM   1657  C CG  . ASP A 1 210 ? 162.519 144.730 149.050 1.00 39.53  ? 211 ASP A CG  1 
ATOM   1658  O OD1 . ASP A 1 210 ? 163.580 145.320 149.331 1.00 41.40  ? 211 ASP A OD1 1 
ATOM   1659  O OD2 . ASP A 1 210 ? 161.711 144.334 149.913 1.00 46.06  ? 211 ASP A OD2 1 
ATOM   1660  N N   . LEU A 1 211 ? 165.312 143.946 147.715 1.00 37.81  ? 212 LEU A N   1 
ATOM   1661  C CA  . LEU A 1 211 ? 166.356 142.947 147.915 1.00 31.26  ? 212 LEU A CA  1 
ATOM   1662  C C   . LEU A 1 211 ? 165.768 141.593 148.287 1.00 38.05  ? 212 LEU A C   1 
ATOM   1663  O O   . LEU A 1 211 ? 166.405 140.557 148.070 1.00 44.43  ? 212 LEU A O   1 
ATOM   1664  C CB  . LEU A 1 211 ? 167.332 143.424 148.993 1.00 29.82  ? 212 LEU A CB  1 
ATOM   1665  C CG  . LEU A 1 211 ? 168.532 142.545 149.347 1.00 32.00  ? 212 LEU A CG  1 
ATOM   1666  C CD1 . LEU A 1 211 ? 169.628 142.679 148.310 1.00 28.79  ? 212 LEU A CD1 1 
ATOM   1667  C CD2 . LEU A 1 211 ? 169.062 142.897 150.723 1.00 33.16  ? 212 LEU A CD2 1 
ATOM   1668  N N   . ARG A 1 212 ? 164.556 141.579 148.835 1.00 39.37  ? 213 ARG A N   1 
ATOM   1669  C CA  . ARG A 1 212 ? 163.886 140.356 149.252 1.00 35.87  ? 213 ARG A CA  1 
ATOM   1670  C C   . ARG A 1 212 ? 163.112 139.687 148.125 1.00 36.07  ? 213 ARG A C   1 
ATOM   1671  O O   . ARG A 1 212 ? 162.544 138.612 148.339 1.00 36.33  ? 213 ARG A O   1 
ATOM   1672  C CB  . ARG A 1 212 ? 162.940 140.653 150.418 1.00 42.40  ? 213 ARG A CB  1 
ATOM   1673  C CG  . ARG A 1 212 ? 163.640 141.174 151.661 1.00 52.45  ? 213 ARG A CG  1 
ATOM   1674  C CD  . ARG A 1 212 ? 162.714 142.042 152.492 1.00 58.36  ? 213 ARG A CD  1 
ATOM   1675  N NE  . ARG A 1 212 ? 163.433 142.746 153.547 1.00 65.51  ? 213 ARG A NE  1 
ATOM   1676  C CZ  . ARG A 1 212 ? 163.074 143.924 154.039 1.00 71.78  ? 213 ARG A CZ  1 
ATOM   1677  N NH1 . ARG A 1 212 ? 162.013 144.569 153.584 1.00 71.71  ? 213 ARG A NH1 1 
ATOM   1678  N NH2 . ARG A 1 212 ? 163.800 144.469 155.011 1.00 67.63  ? 213 ARG A NH2 1 
ATOM   1679  N N   . ASP A 1 213 ? 163.067 140.294 146.942 1.00 36.48  ? 214 ASP A N   1 
ATOM   1680  C CA  . ASP A 1 213 ? 162.394 139.710 145.787 1.00 36.46  ? 214 ASP A CA  1 
ATOM   1681  C C   . ASP A 1 213 ? 163.396 138.840 145.038 1.00 35.13  ? 214 ASP A C   1 
ATOM   1682  O O   . ASP A 1 213 ? 164.305 139.354 144.379 1.00 33.43  ? 214 ASP A O   1 
ATOM   1683  C CB  . ASP A 1 213 ? 161.822 140.801 144.887 1.00 37.30  ? 214 ASP A CB  1 
ATOM   1684  C CG  . ASP A 1 213 ? 160.772 141.640 145.585 1.00 39.20  ? 214 ASP A CG  1 
ATOM   1685  O OD1 . ASP A 1 213 ? 160.249 141.197 146.627 1.00 40.43  ? 214 ASP A OD1 1 
ATOM   1686  O OD2 . ASP A 1 213 ? 160.466 142.744 145.090 1.00 39.60  ? 214 ASP A OD2 1 
ATOM   1687  N N   . ILE A 1 214 ? 163.230 137.522 145.140 1.00 32.08  ? 215 ILE A N   1 
ATOM   1688  C CA  . ILE A 1 214 ? 164.189 136.564 144.608 1.00 29.64  ? 215 ILE A CA  1 
ATOM   1689  C C   . ILE A 1 214 ? 163.561 135.567 143.648 1.00 28.01  ? 215 ILE A C   1 
ATOM   1690  O O   . ILE A 1 214 ? 164.279 134.742 143.080 1.00 29.07  ? 215 ILE A O   1 
ATOM   1691  C CB  . ILE A 1 214 ? 164.919 135.819 145.744 1.00 30.27  ? 215 ILE A CB  1 
ATOM   1692  C CG1 . ILE A 1 214 ? 163.912 135.086 146.630 1.00 33.99  ? 215 ILE A CG1 1 
ATOM   1693  C CG2 . ILE A 1 214 ? 165.746 136.783 146.571 1.00 31.27  ? 215 ILE A CG2 1 
ATOM   1694  C CD1 . ILE A 1 214 ? 164.390 133.745 147.112 1.00 36.38  ? 215 ILE A CD1 1 
ATOM   1695  N N   . GLY A 1 215 ? 162.250 135.616 143.445 1.00 27.36  ? 216 GLY A N   1 
ATOM   1696  C CA  . GLY A 1 215 ? 161.603 134.685 142.542 1.00 29.21  ? 216 GLY A CA  1 
ATOM   1697  C C   . GLY A 1 215 ? 160.467 133.925 143.191 1.00 35.82  ? 216 GLY A C   1 
ATOM   1698  O O   . GLY A 1 215 ? 160.421 133.794 144.417 1.00 39.18  ? 216 GLY A O   1 
ATOM   1699  N N   . ALA A 1 216 ? 159.543 133.416 142.381 1.00 35.80  ? 217 ALA A N   1 
ATOM   1700  C CA  . ALA A 1 216 ? 158.369 132.722 142.883 1.00 35.55  ? 217 ALA A CA  1 
ATOM   1701  C C   . ALA A 1 216 ? 158.245 131.354 142.231 1.00 38.40  ? 217 ALA A C   1 
ATOM   1702  O O   . ALA A 1 216 ? 158.421 131.215 141.018 1.00 38.71  ? 217 ALA A O   1 
ATOM   1703  C CB  . ALA A 1 216 ? 157.096 133.534 142.628 1.00 35.97  ? 217 ALA A CB  1 
ATOM   1704  N N   . GLY A 1 217 ? 157.933 130.354 143.045 1.00 43.14  ? 218 GLY A N   1 
ATOM   1705  C CA  . GLY A 1 217 ? 157.645 129.027 142.525 1.00 44.89  ? 218 GLY A CA  1 
ATOM   1706  C C   . GLY A 1 217 ? 158.863 128.370 141.908 1.00 44.30  ? 218 GLY A C   1 
ATOM   1707  O O   . GLY A 1 217 ? 159.919 128.237 142.537 1.00 43.50  ? 218 GLY A O   1 
ATOM   1708  N N   . LYS A 1 218 ? 158.710 127.940 140.654 1.00 42.45  ? 219 LYS A N   1 
ATOM   1709  C CA  . LYS A 1 218 ? 159.761 127.208 139.958 1.00 41.13  ? 219 LYS A CA  1 
ATOM   1710  C C   . LYS A 1 218 ? 160.973 128.081 139.649 1.00 38.50  ? 219 LYS A C   1 
ATOM   1711  O O   . LYS A 1 218 ? 162.076 127.552 139.475 1.00 35.43  ? 219 LYS A O   1 
ATOM   1712  C CB  . LYS A 1 218 ? 159.174 126.597 138.680 1.00 41.49  ? 219 LYS A CB  1 
ATOM   1713  C CG  . LYS A 1 218 ? 160.161 126.006 137.689 1.00 36.24  ? 219 LYS A CG  1 
ATOM   1714  C CD  . LYS A 1 218 ? 159.819 126.447 136.275 1.00 38.97  ? 219 LYS A CD  1 
ATOM   1715  C CE  . LYS A 1 218 ? 160.865 125.990 135.278 1.00 36.32  ? 219 LYS A CE  1 
ATOM   1716  N NZ  . LYS A 1 218 ? 160.850 126.812 134.036 1.00 30.73  ? 219 LYS A NZ  1 
ATOM   1717  N N   . GLY A 1 219 ? 160.804 129.399 139.610 1.00 35.26  ? 220 GLY A N   1 
ATOM   1718  C CA  . GLY A 1 219 ? 161.907 130.293 139.324 1.00 31.11  ? 220 GLY A CA  1 
ATOM   1719  C C   . GLY A 1 219 ? 162.407 131.054 140.533 1.00 31.66  ? 220 GLY A C   1 
ATOM   1720  O O   . GLY A 1 219 ? 162.733 132.239 140.434 1.00 32.45  ? 220 GLY A O   1 
ATOM   1721  N N   . LYS A 1 220 ? 162.467 130.386 141.682 1.00 34.87  ? 221 LYS A N   1 
ATOM   1722  C CA  . LYS A 1 220 ? 162.982 131.014 142.891 1.00 35.25  ? 221 LYS A CA  1 
ATOM   1723  C C   . LYS A 1 220 ? 164.505 131.031 142.876 1.00 31.20  ? 221 LYS A C   1 
ATOM   1724  O O   . LYS A 1 220 ? 165.145 130.076 142.428 1.00 34.21  ? 221 LYS A O   1 
ATOM   1725  C CB  . LYS A 1 220 ? 162.474 130.277 144.129 1.00 38.35  ? 221 LYS A CB  1 
ATOM   1726  C CG  . LYS A 1 220 ? 162.788 130.978 145.436 1.00 39.33  ? 221 LYS A CG  1 
ATOM   1727  C CD  . LYS A 1 220 ? 161.706 130.740 146.471 1.00 43.19  ? 221 LYS A CD  1 
ATOM   1728  C CE  . LYS A 1 220 ? 162.151 129.718 147.502 1.00 47.71  ? 221 LYS A CE  1 
ATOM   1729  N NZ  . LYS A 1 220 ? 161.980 130.220 148.892 1.00 50.79  ? 221 LYS A NZ  1 
ATOM   1730  N N   . TYR A 1 221 ? 165.079 132.128 143.376 1.00 28.74  ? 222 TYR A N   1 
ATOM   1731  C CA  . TYR A 1 221 ? 166.510 132.435 143.366 1.00 33.20  ? 222 TYR A CA  1 
ATOM   1732  C C   . TYR A 1 221 ? 167.023 132.798 141.979 1.00 30.33  ? 222 TYR A C   1 
ATOM   1733  O O   . TYR A 1 221 ? 168.238 132.925 141.790 1.00 31.61  ? 222 TYR A O   1 
ATOM   1734  C CB  . TYR A 1 221 ? 167.360 131.292 143.939 1.00 37.21  ? 222 TYR A CB  1 
ATOM   1735  C CG  . TYR A 1 221 ? 167.098 130.991 145.398 1.00 43.86  ? 222 TYR A CG  1 
ATOM   1736  C CD1 . TYR A 1 221 ? 167.407 131.916 146.384 1.00 42.06  ? 222 TYR A CD1 1 
ATOM   1737  C CD2 . TYR A 1 221 ? 166.532 129.783 145.786 1.00 45.59  ? 222 TYR A CD2 1 
ATOM   1738  C CE1 . TYR A 1 221 ? 167.168 131.644 147.716 1.00 46.78  ? 222 TYR A CE1 1 
ATOM   1739  C CE2 . TYR A 1 221 ? 166.286 129.504 147.114 1.00 46.14  ? 222 TYR A CE2 1 
ATOM   1740  C CZ  . TYR A 1 221 ? 166.606 130.438 148.075 1.00 52.87  ? 222 TYR A CZ  1 
ATOM   1741  O OH  . TYR A 1 221 ? 166.363 130.163 149.401 1.00 58.59  ? 222 TYR A OH  1 
ATOM   1742  N N   . TYR A 1 222 ? 166.133 132.981 141.005 1.00 27.00  ? 223 TYR A N   1 
ATOM   1743  C CA  . TYR A 1 222 ? 166.509 133.349 139.646 1.00 23.19  ? 223 TYR A CA  1 
ATOM   1744  C C   . TYR A 1 222 ? 166.123 134.789 139.320 1.00 23.88  ? 223 TYR A C   1 
ATOM   1745  O O   . TYR A 1 222 ? 165.783 135.106 138.179 1.00 24.36  ? 223 TYR A O   1 
ATOM   1746  C CB  . TYR A 1 222 ? 165.883 132.385 138.640 1.00 23.68  ? 223 TYR A CB  1 
ATOM   1747  C CG  . TYR A 1 222 ? 166.479 131.001 138.689 1.00 25.48  ? 223 TYR A CG  1 
ATOM   1748  C CD1 . TYR A 1 222 ? 167.644 130.703 138.001 1.00 28.19  ? 223 TYR A CD1 1 
ATOM   1749  C CD2 . TYR A 1 222 ? 165.884 129.996 139.434 1.00 27.52  ? 223 TYR A CD2 1 
ATOM   1750  C CE1 . TYR A 1 222 ? 168.196 129.440 138.051 1.00 33.25  ? 223 TYR A CE1 1 
ATOM   1751  C CE2 . TYR A 1 222 ? 166.430 128.732 139.492 1.00 27.39  ? 223 TYR A CE2 1 
ATOM   1752  C CZ  . TYR A 1 222 ? 167.583 128.459 138.797 1.00 31.29  ? 223 TYR A CZ  1 
ATOM   1753  O OH  . TYR A 1 222 ? 168.130 127.199 138.846 1.00 33.66  ? 223 TYR A OH  1 
ATOM   1754  N N   . ALA A 1 223 ? 166.161 135.666 140.320 1.00 23.18  ? 224 ALA A N   1 
ATOM   1755  C CA  . ALA A 1 223 ? 165.890 137.088 140.132 1.00 17.91  ? 224 ALA A CA  1 
ATOM   1756  C C   . ALA A 1 223 ? 166.755 137.853 141.120 1.00 16.78  ? 224 ALA A C   1 
ATOM   1757  O O   . ALA A 1 223 ? 166.469 137.860 142.320 1.00 21.82  ? 224 ALA A O   1 
ATOM   1758  C CB  . ALA A 1 223 ? 164.409 137.409 140.332 1.00 19.10  ? 224 ALA A CB  1 
ATOM   1759  N N   . VAL A 1 224 ? 167.806 138.493 140.619 1.00 16.67  ? 225 VAL A N   1 
ATOM   1760  C CA  . VAL A 1 224 ? 168.767 139.216 141.443 1.00 14.22  ? 225 VAL A CA  1 
ATOM   1761  C C   . VAL A 1 224 ? 168.453 140.702 141.366 1.00 14.76  ? 225 VAL A C   1 
ATOM   1762  O O   . VAL A 1 224 ? 168.226 141.241 140.276 1.00 15.96  ? 225 VAL A O   1 
ATOM   1763  C CB  . VAL A 1 224 ? 170.209 138.931 140.992 1.00 12.72  ? 225 VAL A CB  1 
ATOM   1764  C CG1 . VAL A 1 224 ? 171.198 139.522 141.972 1.00 16.09  ? 225 VAL A CG1 1 
ATOM   1765  C CG2 . VAL A 1 224 ? 170.431 137.439 140.840 1.00 12.25  ? 225 VAL A CG2 1 
ATOM   1766  N N   . ASN A 1 225 ? 168.426 141.363 142.522 1.00 16.99  ? 226 ASN A N   1 
ATOM   1767  C CA  . ASN A 1 225 ? 168.133 142.787 142.615 1.00 17.30  ? 226 ASN A CA  1 
ATOM   1768  C C   . ASN A 1 225 ? 169.176 143.453 143.498 1.00 20.63  ? 226 ASN A C   1 
ATOM   1769  O O   . ASN A 1 225 ? 169.440 142.986 144.609 1.00 24.94  ? 226 ASN A O   1 
ATOM   1770  C CB  . ASN A 1 225 ? 166.731 143.026 143.180 1.00 17.53  ? 226 ASN A CB  1 
ATOM   1771  C CG  . ASN A 1 225 ? 165.641 142.759 142.166 1.00 18.56  ? 226 ASN A CG  1 
ATOM   1772  O OD1 . ASN A 1 225 ? 165.884 142.766 140.962 1.00 20.30  ? 226 ASN A OD1 1 
ATOM   1773  N ND2 . ASN A 1 225 ? 164.433 142.510 142.649 1.00 20.93  ? 226 ASN A ND2 1 
ATOM   1774  N N   . PHE A 1 226 ? 169.764 144.545 143.007 1.00 19.74  ? 227 PHE A N   1 
ATOM   1775  C CA  . PHE A 1 226 ? 170.777 145.302 143.741 1.00 20.76  ? 227 PHE A CA  1 
ATOM   1776  C C   . PHE A 1 226 ? 170.266 146.722 143.950 1.00 22.80  ? 227 PHE A C   1 
ATOM   1777  O O   . PHE A 1 226 ? 170.520 147.611 143.123 1.00 23.24  ? 227 PHE A O   1 
ATOM   1778  C CB  . PHE A 1 226 ? 172.114 145.304 143.003 1.00 19.21  ? 227 PHE A CB  1 
ATOM   1779  C CG  . PHE A 1 226 ? 173.303 145.506 143.902 1.00 20.95  ? 227 PHE A CG  1 
ATOM   1780  C CD1 . PHE A 1 226 ? 173.456 146.680 144.621 1.00 19.84  ? 227 PHE A CD1 1 
ATOM   1781  C CD2 . PHE A 1 226 ? 174.267 144.523 144.026 1.00 23.05  ? 227 PHE A CD2 1 
ATOM   1782  C CE1 . PHE A 1 226 ? 174.544 146.864 145.448 1.00 21.81  ? 227 PHE A CE1 1 
ATOM   1783  C CE2 . PHE A 1 226 ? 175.358 144.703 144.852 1.00 24.73  ? 227 PHE A CE2 1 
ATOM   1784  C CZ  . PHE A 1 226 ? 175.497 145.875 145.563 1.00 24.96  ? 227 PHE A CZ  1 
ATOM   1785  N N   . PRO A 1 227 ? 169.546 146.979 145.040 1.00 23.48  ? 228 PRO A N   1 
ATOM   1786  C CA  . PRO A 1 227 ? 169.083 148.341 145.317 1.00 19.45  ? 228 PRO A CA  1 
ATOM   1787  C C   . PRO A 1 227 ? 170.245 149.279 145.602 1.00 22.55  ? 228 PRO A C   1 
ATOM   1788  O O   . PRO A 1 227 ? 171.274 148.882 146.152 1.00 28.04  ? 228 PRO A O   1 
ATOM   1789  C CB  . PRO A 1 227 ? 168.195 148.167 146.553 1.00 23.18  ? 228 PRO A CB  1 
ATOM   1790  C CG  . PRO A 1 227 ? 168.649 146.898 147.175 1.00 23.38  ? 228 PRO A CG  1 
ATOM   1791  C CD  . PRO A 1 227 ? 169.092 146.018 146.058 1.00 25.09  ? 228 PRO A CD  1 
ATOM   1792  N N   . MET A 1 228 ? 170.064 150.544 145.232 1.00 23.85  ? 229 MET A N   1 
ATOM   1793  C CA  . MET A 1 228 ? 171.112 151.546 145.348 1.00 20.29  ? 229 MET A CA  1 
ATOM   1794  C C   . MET A 1 228 ? 170.568 152.776 146.061 1.00 20.99  ? 229 MET A C   1 
ATOM   1795  O O   . MET A 1 228 ? 169.382 152.867 146.387 1.00 21.28  ? 229 MET A O   1 
ATOM   1796  C CB  . MET A 1 228 ? 171.654 151.952 143.974 1.00 20.70  ? 229 MET A CB  1 
ATOM   1797  C CG  . MET A 1 228 ? 172.946 151.286 143.576 1.00 19.16  ? 229 MET A CG  1 
ATOM   1798  S SD  . MET A 1 228 ? 172.966 151.059 141.795 1.00 27.22  ? 229 MET A SD  1 
ATOM   1799  C CE  . MET A 1 228 ? 173.887 149.548 141.662 1.00 18.52  ? 229 MET A CE  1 
ATOM   1800  N N   . ARG A 1 229 ? 171.459 153.730 146.293 1.00 22.82  ? 230 ARG A N   1 
ATOM   1801  C CA  . ARG A 1 229 ? 171.130 155.043 146.823 1.00 22.61  ? 230 ARG A CA  1 
ATOM   1802  C C   . ARG A 1 229 ? 171.603 156.106 145.832 1.00 26.42  ? 230 ARG A C   1 
ATOM   1803  O O   . ARG A 1 229 ? 172.036 155.799 144.720 1.00 32.68  ? 230 ARG A O   1 
ATOM   1804  C CB  . ARG A 1 229 ? 171.745 155.236 148.210 1.00 24.73  ? 230 ARG A CB  1 
ATOM   1805  C CG  . ARG A 1 229 ? 171.021 154.492 149.314 1.00 23.98  ? 230 ARG A CG  1 
ATOM   1806  C CD  . ARG A 1 229 ? 171.975 154.022 150.389 1.00 26.72  ? 230 ARG A CD  1 
ATOM   1807  N NE  . ARG A 1 229 ? 171.277 153.737 151.637 1.00 33.69  ? 230 ARG A NE  1 
ATOM   1808  C CZ  . ARG A 1 229 ? 171.852 153.720 152.832 1.00 35.66  ? 230 ARG A CZ  1 
ATOM   1809  N NH1 . ARG A 1 229 ? 173.142 153.969 152.981 1.00 33.81  ? 230 ARG A NH1 1 
ATOM   1810  N NH2 . ARG A 1 229 ? 171.113 153.448 153.903 1.00 38.30  ? 230 ARG A NH2 1 
ATOM   1811  N N   . ASP A 1 230 ? 171.517 157.363 146.245 1.00 25.54  ? 231 ASP A N   1 
ATOM   1812  C CA  . ASP A 1 230 ? 171.816 158.476 145.360 1.00 24.83  ? 231 ASP A CA  1 
ATOM   1813  C C   . ASP A 1 230 ? 173.318 158.675 145.198 1.00 28.52  ? 231 ASP A C   1 
ATOM   1814  O O   . ASP A 1 230 ? 174.103 158.454 146.123 1.00 29.87  ? 231 ASP A O   1 
ATOM   1815  C CB  . ASP A 1 230 ? 171.193 159.759 145.901 1.00 26.87  ? 231 ASP A CB  1 
ATOM   1816  C CG  . ASP A 1 230 ? 169.734 159.593 146.237 1.00 36.93  ? 231 ASP A CG  1 
ATOM   1817  O OD1 . ASP A 1 230 ? 168.912 159.601 145.301 1.00 44.06  ? 231 ASP A OD1 1 
ATOM   1818  O OD2 . ASP A 1 230 ? 169.408 159.448 147.434 1.00 34.36  ? 231 ASP A OD2 1 
ATOM   1819  N N   . GLY A 1 231 ? 173.711 159.102 144.000 1.00 26.01  ? 232 GLY A N   1 
ATOM   1820  C CA  . GLY A 1 231 ? 175.051 159.602 143.781 1.00 21.86  ? 232 GLY A CA  1 
ATOM   1821  C C   . GLY A 1 231 ? 176.136 158.571 143.599 1.00 22.34  ? 232 GLY A C   1 
ATOM   1822  O O   . GLY A 1 231 ? 177.311 158.902 143.781 1.00 28.16  ? 232 GLY A O   1 
ATOM   1823  N N   . ILE A 1 232 ? 175.792 157.332 143.241 1.00 21.46  ? 233 ILE A N   1 
ATOM   1824  C CA  . ILE A 1 232 ? 176.819 156.319 143.032 1.00 22.49  ? 233 ILE A CA  1 
ATOM   1825  C C   . ILE A 1 232 ? 177.714 156.734 141.871 1.00 21.68  ? 233 ILE A C   1 
ATOM   1826  O O   . ILE A 1 232 ? 177.259 157.334 140.890 1.00 23.92  ? 233 ILE A O   1 
ATOM   1827  C CB  . ILE A 1 232 ? 176.183 154.936 142.800 1.00 19.76  ? 233 ILE A CB  1 
ATOM   1828  C CG1 . ILE A 1 232 ? 177.232 153.835 142.955 1.00 23.51  ? 233 ILE A CG1 1 
ATOM   1829  C CG2 . ILE A 1 232 ? 175.533 154.853 141.438 1.00 19.86  ? 233 ILE A CG2 1 
ATOM   1830  C CD1 . ILE A 1 232 ? 176.652 152.464 143.172 1.00 20.14  ? 233 ILE A CD1 1 
ATOM   1831  N N   . ASP A 1 233 ? 179.003 156.441 141.994 1.00 22.15  ? 234 ASP A N   1 
ATOM   1832  C CA  . ASP A 1 233 ? 180.001 156.868 141.026 1.00 21.82  ? 234 ASP A CA  1 
ATOM   1833  C C   . ASP A 1 233 ? 180.609 155.658 140.322 1.00 24.72  ? 234 ASP A C   1 
ATOM   1834  O O   . ASP A 1 233 ? 180.187 154.515 140.512 1.00 23.39  ? 234 ASP A O   1 
ATOM   1835  C CB  . ASP A 1 233 ? 181.077 157.719 141.705 1.00 24.32  ? 234 ASP A CB  1 
ATOM   1836  C CG  . ASP A 1 233 ? 181.844 156.958 142.769 1.00 34.45  ? 234 ASP A CG  1 
ATOM   1837  O OD1 . ASP A 1 233 ? 181.208 156.242 143.569 1.00 38.51  ? 234 ASP A OD1 1 
ATOM   1838  O OD2 . ASP A 1 233 ? 183.085 157.080 142.809 1.00 32.93  ? 234 ASP A OD2 1 
ATOM   1839  N N   . ASP A 1 234 ? 181.613 155.931 139.485 1.00 25.37  ? 235 ASP A N   1 
ATOM   1840  C CA  . ASP A 1 234 ? 182.229 154.882 138.679 1.00 23.87  ? 235 ASP A CA  1 
ATOM   1841  C C   . ASP A 1 234 ? 182.941 153.849 139.541 1.00 27.55  ? 235 ASP A C   1 
ATOM   1842  O O   . ASP A 1 234 ? 182.885 152.649 139.250 1.00 27.40  ? 235 ASP A O   1 
ATOM   1843  C CB  . ASP A 1 234 ? 183.208 155.496 137.682 1.00 23.70  ? 235 ASP A CB  1 
ATOM   1844  C CG  . ASP A 1 234 ? 182.515 156.270 136.591 1.00 25.86  ? 235 ASP A CG  1 
ATOM   1845  O OD1 . ASP A 1 234 ? 181.271 156.240 136.542 1.00 25.79  ? 235 ASP A OD1 1 
ATOM   1846  O OD2 . ASP A 1 234 ? 183.214 156.906 135.777 1.00 27.60  ? 235 ASP A OD2 1 
ATOM   1847  N N   . GLU A 1 235 ? 183.630 154.294 140.593 1.00 29.28  ? 236 GLU A N   1 
ATOM   1848  C CA  . GLU A 1 235 ? 184.420 153.376 141.407 1.00 32.18  ? 236 GLU A CA  1 
ATOM   1849  C C   . GLU A 1 235 ? 183.533 152.363 142.121 1.00 30.16  ? 236 GLU A C   1 
ATOM   1850  O O   . GLU A 1 235 ? 183.791 151.156 142.075 1.00 32.51  ? 236 GLU A O   1 
ATOM   1851  C CB  . GLU A 1 235 ? 185.259 154.161 142.413 1.00 38.52  ? 236 GLU A CB  1 
ATOM   1852  C CG  . GLU A 1 235 ? 186.654 153.603 142.624 1.00 47.43  ? 236 GLU A CG  1 
ATOM   1853  C CD  . GLU A 1 235 ? 187.123 153.736 144.058 1.00 57.75  ? 236 GLU A CD  1 
ATOM   1854  O OE1 . GLU A 1 235 ? 188.136 153.099 144.415 1.00 60.93  ? 236 GLU A OE1 1 
ATOM   1855  O OE2 . GLU A 1 235 ? 186.478 154.477 144.830 1.00 58.64  ? 236 GLU A OE2 1 
ATOM   1856  N N   . SER A 1 236 ? 182.475 152.838 142.783 1.00 27.85  ? 237 SER A N   1 
ATOM   1857  C CA  . SER A 1 236 ? 181.582 151.933 143.501 1.00 28.57  ? 237 SER A CA  1 
ATOM   1858  C C   . SER A 1 236 ? 180.856 150.994 142.546 1.00 29.18  ? 237 SER A C   1 
ATOM   1859  O O   . SER A 1 236 ? 180.720 149.792 142.820 1.00 27.66  ? 237 SER A O   1 
ATOM   1860  C CB  . SER A 1 236 ? 180.577 152.740 144.320 1.00 30.22  ? 237 SER A CB  1 
ATOM   1861  O OG  . SER A 1 236 ? 181.210 153.822 144.974 1.00 35.31  ? 237 SER A OG  1 
ATOM   1862  N N   . TYR A 1 237 ? 180.376 151.527 141.421 1.00 25.37  ? 238 TYR A N   1 
ATOM   1863  C CA  . TYR A 1 237 ? 179.665 150.702 140.452 1.00 19.60  ? 238 TYR A CA  1 
ATOM   1864  C C   . TYR A 1 237 ? 180.571 149.619 139.887 1.00 21.62  ? 238 TYR A C   1 
ATOM   1865  O O   . TYR A 1 237 ? 180.151 148.468 139.736 1.00 23.20  ? 238 TYR A O   1 
ATOM   1866  C CB  . TYR A 1 237 ? 179.104 151.578 139.333 1.00 20.02  ? 238 TYR A CB  1 
ATOM   1867  C CG  . TYR A 1 237 ? 177.779 151.100 138.786 1.00 22.44  ? 238 TYR A CG  1 
ATOM   1868  C CD1 . TYR A 1 237 ? 177.723 150.119 137.806 1.00 19.19  ? 238 TYR A CD1 1 
ATOM   1869  C CD2 . TYR A 1 237 ? 176.585 151.630 139.248 1.00 19.20  ? 238 TYR A CD2 1 
ATOM   1870  C CE1 . TYR A 1 237 ? 176.517 149.680 137.305 1.00 14.54  ? 238 TYR A CE1 1 
ATOM   1871  C CE2 . TYR A 1 237 ? 175.377 151.199 138.751 1.00 19.05  ? 238 TYR A CE2 1 
ATOM   1872  C CZ  . TYR A 1 237 ? 175.349 150.223 137.780 1.00 17.97  ? 238 TYR A CZ  1 
ATOM   1873  O OH  . TYR A 1 237 ? 174.142 149.791 137.283 1.00 17.03  ? 238 TYR A OH  1 
ATOM   1874  N N   . GLY A 1 238 ? 181.818 149.968 139.564 1.00 21.57  ? 239 GLY A N   1 
ATOM   1875  C CA  . GLY A 1 238 ? 182.763 148.965 139.108 1.00 21.46  ? 239 GLY A CA  1 
ATOM   1876  C C   . GLY A 1 238 ? 183.124 147.957 140.177 1.00 24.39  ? 239 GLY A C   1 
ATOM   1877  O O   . GLY A 1 238 ? 183.354 146.784 139.873 1.00 26.36  ? 239 GLY A O   1 
ATOM   1878  N N   . GLN A 1 239 ? 183.186 148.395 141.436 1.00 25.76  ? 240 GLN A N   1 
ATOM   1879  C CA  . GLN A 1 239 ? 183.496 147.479 142.526 1.00 25.32  ? 240 GLN A CA  1 
ATOM   1880  C C   . GLN A 1 239 ? 182.381 146.470 142.747 1.00 23.60  ? 240 GLN A C   1 
ATOM   1881  O O   . GLN A 1 239 ? 182.648 145.333 143.146 1.00 27.32  ? 240 GLN A O   1 
ATOM   1882  C CB  . GLN A 1 239 ? 183.753 148.260 143.814 1.00 30.11  ? 240 GLN A CB  1 
ATOM   1883  C CG  . GLN A 1 239 ? 185.170 148.787 143.962 1.00 35.05  ? 240 GLN A CG  1 
ATOM   1884  C CD  . GLN A 1 239 ? 185.330 149.674 145.180 1.00 43.92  ? 240 GLN A CD  1 
ATOM   1885  O OE1 . GLN A 1 239 ? 184.682 149.463 146.204 1.00 44.65  ? 240 GLN A OE1 1 
ATOM   1886  N NE2 . GLN A 1 239 ? 186.192 150.676 145.073 1.00 44.46  ? 240 GLN A NE2 1 
ATOM   1887  N N   . ILE A 1 240 ? 181.131 146.866 142.511 1.00 24.51  ? 241 ILE A N   1 
ATOM   1888  C CA  . ILE A 1 240 ? 180.015 145.956 142.749 1.00 22.27  ? 241 ILE A CA  1 
ATOM   1889  C C   . ILE A 1 240 ? 179.559 145.187 141.511 1.00 21.34  ? 241 ILE A C   1 
ATOM   1890  O O   . ILE A 1 240 ? 178.887 144.157 141.654 1.00 22.78  ? 241 ILE A O   1 
ATOM   1891  C CB  . ILE A 1 240 ? 178.803 146.702 143.330 1.00 23.95  ? 241 ILE A CB  1 
ATOM   1892  C CG1 . ILE A 1 240 ? 178.262 147.695 142.308 1.00 24.33  ? 241 ILE A CG1 1 
ATOM   1893  C CG2 . ILE A 1 240 ? 179.181 147.408 144.610 1.00 29.52  ? 241 ILE A CG2 1 
ATOM   1894  C CD1 . ILE A 1 240 ? 176.795 147.898 142.404 1.00 21.75  ? 241 ILE A CD1 1 
ATOM   1895  N N   . PHE A 1 241 ? 179.889 145.652 140.305 1.00 20.37  ? 242 PHE A N   1 
ATOM   1896  C CA  . PHE A 1 241 ? 179.345 145.024 139.106 1.00 17.68  ? 242 PHE A CA  1 
ATOM   1897  C C   . PHE A 1 241 ? 180.113 143.764 138.728 1.00 17.50  ? 242 PHE A C   1 
ATOM   1898  O O   . PHE A 1 241 ? 179.513 142.708 138.506 1.00 17.73  ? 242 PHE A O   1 
ATOM   1899  C CB  . PHE A 1 241 ? 179.347 146.028 137.948 1.00 17.27  ? 242 PHE A CB  1 
ATOM   1900  C CG  . PHE A 1 241 ? 178.685 145.519 136.696 1.00 16.41  ? 242 PHE A CG  1 
ATOM   1901  C CD1 . PHE A 1 241 ? 177.314 145.613 136.535 1.00 14.25  ? 242 PHE A CD1 1 
ATOM   1902  C CD2 . PHE A 1 241 ? 179.434 144.957 135.677 1.00 14.62  ? 242 PHE A CD2 1 
ATOM   1903  C CE1 . PHE A 1 241 ? 176.706 145.150 135.389 1.00 11.97  ? 242 PHE A CE1 1 
ATOM   1904  C CE2 . PHE A 1 241 ? 178.828 144.490 134.529 1.00 14.27  ? 242 PHE A CE2 1 
ATOM   1905  C CZ  . PHE A 1 241 ? 177.463 144.588 134.386 1.00 11.66  ? 242 PHE A CZ  1 
ATOM   1906  N N   . LYS A 1 242 ? 181.438 143.861 138.641 1.00 17.80  ? 243 LYS A N   1 
ATOM   1907  C CA  . LYS A 1 242 ? 182.242 142.721 138.202 1.00 18.31  ? 243 LYS A CA  1 
ATOM   1908  C C   . LYS A 1 242 ? 182.123 141.508 139.119 1.00 20.94  ? 243 LYS A C   1 
ATOM   1909  O O   . LYS A 1 242 ? 181.972 140.388 138.599 1.00 21.21  ? 243 LYS A O   1 
ATOM   1910  C CB  . LYS A 1 242 ? 183.698 143.167 138.032 1.00 20.69  ? 243 LYS A CB  1 
ATOM   1911  C CG  . LYS A 1 242 ? 184.647 142.066 137.602 1.00 22.44  ? 243 LYS A CG  1 
ATOM   1912  C CD  . LYS A 1 242 ? 185.895 142.640 136.956 1.00 23.21  ? 243 LYS A CD  1 
ATOM   1913  C CE  . LYS A 1 242 ? 186.554 141.628 136.038 1.00 30.71  ? 243 LYS A CE  1 
ATOM   1914  N NZ  . LYS A 1 242 ? 186.507 142.052 134.611 1.00 35.02  ? 243 LYS A NZ  1 
ATOM   1915  N N   . PRO A 1 243 ? 182.196 141.631 140.454 1.00 21.27  ? 244 PRO A N   1 
ATOM   1916  C CA  . PRO A 1 243 ? 182.017 140.433 141.296 1.00 18.39  ? 244 PRO A CA  1 
ATOM   1917  C C   . PRO A 1 243 ? 180.663 139.764 141.141 1.00 21.06  ? 244 PRO A C   1 
ATOM   1918  O O   . PRO A 1 243 ? 180.592 138.532 141.041 1.00 24.86  ? 244 PRO A O   1 
ATOM   1919  C CB  . PRO A 1 243 ? 182.212 140.978 142.716 1.00 20.66  ? 244 PRO A CB  1 
ATOM   1920  C CG  . PRO A 1 243 ? 183.061 142.169 142.543 1.00 19.03  ? 244 PRO A CG  1 
ATOM   1921  C CD  . PRO A 1 243 ? 182.619 142.790 141.261 1.00 20.53  ? 244 PRO A CD  1 
ATOM   1922  N N   . ILE A 1 244 ? 179.581 140.544 141.127 1.00 20.61  ? 245 ILE A N   1 
ATOM   1923  C CA  . ILE A 1 244 ? 178.245 139.966 141.009 1.00 18.47  ? 245 ILE A CA  1 
ATOM   1924  C C   . ILE A 1 244 ? 178.089 139.256 139.673 1.00 18.01  ? 245 ILE A C   1 
ATOM   1925  O O   . ILE A 1 244 ? 177.548 138.148 139.601 1.00 20.45  ? 245 ILE A O   1 
ATOM   1926  C CB  . ILE A 1 244 ? 177.172 141.053 141.203 1.00 18.22  ? 245 ILE A CB  1 
ATOM   1927  C CG1 . ILE A 1 244 ? 177.247 141.640 142.615 1.00 22.15  ? 245 ILE A CG1 1 
ATOM   1928  C CG2 . ILE A 1 244 ? 175.787 140.495 140.920 1.00 16.68  ? 245 ILE A CG2 1 
ATOM   1929  C CD1 . ILE A 1 244 ? 176.536 140.820 143.664 1.00 25.65  ? 245 ILE A CD1 1 
ATOM   1930  N N   . ILE A 1 245 ? 178.564 139.880 138.594 1.00 17.95  ? 246 ILE A N   1 
ATOM   1931  C CA  . ILE A 1 245 ? 178.413 139.290 137.269 1.00 20.11  ? 246 ILE A CA  1 
ATOM   1932  C C   . ILE A 1 245 ? 179.266 138.034 137.141 1.00 18.71  ? 246 ILE A C   1 
ATOM   1933  O O   . ILE A 1 245 ? 178.843 137.042 136.539 1.00 21.86  ? 246 ILE A O   1 
ATOM   1934  C CB  . ILE A 1 245 ? 178.744 140.333 136.185 1.00 19.64  ? 246 ILE A CB  1 
ATOM   1935  C CG1 . ILE A 1 245 ? 177.644 141.394 136.126 1.00 14.60  ? 246 ILE A CG1 1 
ATOM   1936  C CG2 . ILE A 1 245 ? 178.914 139.679 134.823 1.00 18.39  ? 246 ILE A CG2 1 
ATOM   1937  C CD1 . ILE A 1 245 ? 176.245 140.827 136.080 1.00 11.06  ? 246 ILE A CD1 1 
ATOM   1938  N N   . SER A 1 246 ? 180.469 138.044 137.721 1.00 18.92  ? 247 SER A N   1 
ATOM   1939  C CA  . SER A 1 246 ? 181.303 136.846 137.700 1.00 21.57  ? 247 SER A CA  1 
ATOM   1940  C C   . SER A 1 246 ? 180.658 135.708 138.481 1.00 25.31  ? 247 SER A C   1 
ATOM   1941  O O   . SER A 1 246 ? 180.687 134.550 138.045 1.00 25.61  ? 247 SER A O   1 
ATOM   1942  C CB  . SER A 1 246 ? 182.688 137.163 138.259 1.00 23.87  ? 247 SER A CB  1 
ATOM   1943  O OG  . SER A 1 246 ? 183.250 138.293 137.618 1.00 23.46  ? 247 SER A OG  1 
ATOM   1944  N N   . LYS A 1 247 ? 180.067 136.015 139.638 1.00 26.92  ? 248 LYS A N   1 
ATOM   1945  C CA  . LYS A 1 247 ? 179.391 134.982 140.416 1.00 26.20  ? 248 LYS A CA  1 
ATOM   1946  C C   . LYS A 1 247 ? 178.178 134.431 139.676 1.00 24.21  ? 248 LYS A C   1 
ATOM   1947  O O   . LYS A 1 247 ? 177.920 133.222 139.709 1.00 28.88  ? 248 LYS A O   1 
ATOM   1948  C CB  . LYS A 1 247 ? 178.985 135.538 141.779 1.00 30.90  ? 248 LYS A CB  1 
ATOM   1949  C CG  . LYS A 1 247 ? 178.602 134.475 142.789 1.00 37.27  ? 248 LYS A CG  1 
ATOM   1950  C CD  . LYS A 1 247 ? 179.750 134.186 143.736 1.00 36.68  ? 248 LYS A CD  1 
ATOM   1951  C CE  . LYS A 1 247 ? 179.675 132.769 144.265 1.00 40.77  ? 248 LYS A CE  1 
ATOM   1952  N NZ  . LYS A 1 247 ? 178.330 132.468 144.822 1.00 40.49  ? 248 LYS A NZ  1 
ATOM   1953  N N   . VAL A 1 248 ? 177.413 135.304 139.016 1.00 23.58  ? 249 VAL A N   1 
ATOM   1954  C CA  . VAL A 1 248 ? 176.262 134.852 138.237 1.00 24.60  ? 249 VAL A CA  1 
ATOM   1955  C C   . VAL A 1 248 ? 176.716 133.967 137.083 1.00 25.94  ? 249 VAL A C   1 
ATOM   1956  O O   . VAL A 1 248 ? 176.078 132.956 136.769 1.00 26.55  ? 249 VAL A O   1 
ATOM   1957  C CB  . VAL A 1 248 ? 175.443 136.059 137.741 1.00 21.78  ? 249 VAL A CB  1 
ATOM   1958  C CG1 . VAL A 1 248 ? 174.406 135.615 136.733 1.00 19.51  ? 249 VAL A CG1 1 
ATOM   1959  C CG2 . VAL A 1 248 ? 174.773 136.761 138.906 1.00 19.22  ? 249 VAL A CG2 1 
ATOM   1960  N N   . MET A 1 249 ? 177.823 134.332 136.433 1.00 26.35  ? 250 MET A N   1 
ATOM   1961  C CA  . MET A 1 249 ? 178.382 133.487 135.382 1.00 25.19  ? 250 MET A CA  1 
ATOM   1962  C C   . MET A 1 249 ? 178.786 132.121 135.925 1.00 27.83  ? 250 MET A C   1 
ATOM   1963  O O   . MET A 1 249 ? 178.537 131.093 135.285 1.00 30.42  ? 250 MET A O   1 
ATOM   1964  C CB  . MET A 1 249 ? 179.586 134.177 134.744 1.00 25.97  ? 250 MET A CB  1 
ATOM   1965  C CG  . MET A 1 249 ? 179.262 135.213 133.683 1.00 24.80  ? 250 MET A CG  1 
ATOM   1966  S SD  . MET A 1 249 ? 178.094 134.657 132.433 1.00 39.99  ? 250 MET A SD  1 
ATOM   1967  C CE  . MET A 1 249 ? 177.460 136.229 131.864 1.00 25.22  ? 250 MET A CE  1 
ATOM   1968  N N   . GLU A 1 250 ? 179.424 132.093 137.098 1.00 30.48  ? 251 GLU A N   1 
ATOM   1969  C CA  . GLU A 1 250 ? 179.864 130.824 137.673 1.00 28.71  ? 251 GLU A CA  1 
ATOM   1970  C C   . GLU A 1 250 ? 178.683 129.933 138.036 1.00 27.33  ? 251 GLU A C   1 
ATOM   1971  O O   . GLU A 1 250 ? 178.698 128.728 137.761 1.00 32.10  ? 251 GLU A O   1 
ATOM   1972  C CB  . GLU A 1 250 ? 180.733 131.076 138.904 1.00 30.59  ? 251 GLU A CB  1 
ATOM   1973  C CG  . GLU A 1 250 ? 182.146 131.541 138.594 1.00 38.57  ? 251 GLU A CG  1 
ATOM   1974  C CD  . GLU A 1 250 ? 182.791 132.264 139.762 1.00 47.60  ? 251 GLU A CD  1 
ATOM   1975  O OE1 . GLU A 1 250 ? 182.279 132.140 140.895 1.00 46.88  ? 251 GLU A OE1 1 
ATOM   1976  O OE2 . GLU A 1 250 ? 183.807 132.958 139.547 1.00 39.09  ? 251 GLU A OE2 1 
ATOM   1977  N N   . MET A 1 251 ? 177.647 130.505 138.651 1.00 28.72  ? 252 MET A N   1 
ATOM   1978  C CA  . MET A 1 251 ? 176.535 129.697 139.144 1.00 27.88  ? 252 MET A CA  1 
ATOM   1979  C C   . MET A 1 251 ? 175.553 129.345 138.032 1.00 29.91  ? 252 MET A C   1 
ATOM   1980  O O   . MET A 1 251 ? 175.288 128.167 137.771 1.00 34.02  ? 252 MET A O   1 
ATOM   1981  C CB  . MET A 1 251 ? 175.814 130.430 140.279 1.00 30.20  ? 252 MET A CB  1 
ATOM   1982  C CG  . MET A 1 251 ? 176.698 130.789 141.462 1.00 33.77  ? 252 MET A CG  1 
ATOM   1983  S SD  . MET A 1 251 ? 177.240 129.346 142.396 1.00 42.14  ? 252 MET A SD  1 
ATOM   1984  C CE  . MET A 1 251 ? 178.985 129.322 142.004 1.00 37.12  ? 252 MET A CE  1 
ATOM   1985  N N   . TYR A 1 252 ? 174.991 130.362 137.376 1.00 29.43  ? 253 TYR A N   1 
ATOM   1986  C CA  . TYR A 1 252 ? 173.950 130.134 136.379 1.00 23.18  ? 253 TYR A CA  1 
ATOM   1987  C C   . TYR A 1 252 ? 174.496 129.430 135.144 1.00 24.97  ? 253 TYR A C   1 
ATOM   1988  O O   . TYR A 1 252 ? 173.879 128.489 134.632 1.00 27.35  ? 253 TYR A O   1 
ATOM   1989  C CB  . TYR A 1 252 ? 173.310 131.464 135.991 1.00 21.89  ? 253 TYR A CB  1 
ATOM   1990  C CG  . TYR A 1 252 ? 171.988 131.314 135.291 1.00 23.77  ? 253 TYR A CG  1 
ATOM   1991  C CD1 . TYR A 1 252 ? 171.019 130.458 135.783 1.00 25.24  ? 253 TYR A CD1 1 
ATOM   1992  C CD2 . TYR A 1 252 ? 171.713 132.019 134.128 1.00 19.64  ? 253 TYR A CD2 1 
ATOM   1993  C CE1 . TYR A 1 252 ? 169.811 130.315 135.146 1.00 25.72  ? 253 TYR A CE1 1 
ATOM   1994  C CE2 . TYR A 1 252 ? 170.511 131.880 133.485 1.00 16.78  ? 253 TYR A CE2 1 
ATOM   1995  C CZ  . TYR A 1 252 ? 169.564 131.027 133.998 1.00 21.35  ? 253 TYR A CZ  1 
ATOM   1996  O OH  . TYR A 1 252 ? 168.357 130.878 133.366 1.00 25.65  ? 253 TYR A OH  1 
ATOM   1997  N N   . GLN A 1 253 ? 175.648 129.881 134.647 1.00 26.37  ? 254 GLN A N   1 
ATOM   1998  C CA  . GLN A 1 253 ? 176.243 129.399 133.405 1.00 27.47  ? 254 GLN A CA  1 
ATOM   1999  C C   . GLN A 1 253 ? 175.265 129.558 132.246 1.00 28.69  ? 254 GLN A C   1 
ATOM   2000  O O   . GLN A 1 253 ? 174.746 128.558 131.734 1.00 28.75  ? 254 GLN A O   1 
ATOM   2001  C CB  . GLN A 1 253 ? 176.682 127.940 133.537 1.00 27.91  ? 254 GLN A CB  1 
ATOM   2002  C CG  . GLN A 1 253 ? 178.113 127.762 134.003 1.00 29.66  ? 254 GLN A CG  1 
ATOM   2003  C CD  . GLN A 1 253 ? 178.243 126.696 135.067 1.00 36.63  ? 254 GLN A CD  1 
ATOM   2004  O OE1 . GLN A 1 253 ? 177.456 125.751 135.113 1.00 41.54  ? 254 GLN A OE1 1 
ATOM   2005  N NE2 . GLN A 1 253 ? 179.240 126.840 135.931 1.00 35.02  ? 254 GLN A NE2 1 
ATOM   2006  N N   . PRO A 1 254 ? 174.980 130.781 131.812 1.00 25.31  ? 255 PRO A N   1 
ATOM   2007  C CA  . PRO A 1 254 ? 174.042 130.990 130.707 1.00 19.04  ? 255 PRO A CA  1 
ATOM   2008  C C   . PRO A 1 254 ? 174.718 130.742 129.362 1.00 19.75  ? 255 PRO A C   1 
ATOM   2009  O O   . PRO A 1 254 ? 175.925 130.529 129.270 1.00 20.71  ? 255 PRO A O   1 
ATOM   2010  C CB  . PRO A 1 254 ? 173.642 132.455 130.871 1.00 18.03  ? 255 PRO A CB  1 
ATOM   2011  C CG  . PRO A 1 254 ? 174.835 133.091 131.470 1.00 18.32  ? 255 PRO A CG  1 
ATOM   2012  C CD  . PRO A 1 254 ? 175.504 132.056 132.334 1.00 22.72  ? 255 PRO A CD  1 
ATOM   2013  N N   . SER A 1 255 ? 173.905 130.771 128.306 1.00 17.31  ? 256 SER A N   1 
ATOM   2014  C CA  . SER A 1 255 ? 174.390 130.628 126.943 1.00 15.84  ? 256 SER A CA  1 
ATOM   2015  C C   . SER A 1 255 ? 174.159 131.856 126.076 1.00 16.92  ? 256 SER A C   1 
ATOM   2016  O O   . SER A 1 255 ? 174.775 131.958 125.011 1.00 17.00  ? 256 SER A O   1 
ATOM   2017  C CB  . SER A 1 255 ? 173.738 129.414 126.266 1.00 20.16  ? 256 SER A CB  1 
ATOM   2018  O OG  . SER A 1 255 ? 172.370 129.317 126.611 1.00 23.27  ? 256 SER A OG  1 
ATOM   2019  N N   . ALA A 1 256 ? 173.294 132.777 126.492 1.00 16.20  ? 257 ALA A N   1 
ATOM   2020  C CA  . ALA A 1 256 ? 173.085 134.036 125.797 1.00 10.51  ? 257 ALA A CA  1 
ATOM   2021  C C   . ALA A 1 256 ? 172.905 135.137 126.829 1.00 12.23  ? 257 ALA A C   1 
ATOM   2022  O O   . ALA A 1 256 ? 172.460 134.887 127.950 1.00 14.79  ? 257 ALA A O   1 
ATOM   2023  C CB  . ALA A 1 256 ? 171.870 133.982 124.868 1.00 11.30  ? 257 ALA A CB  1 
ATOM   2024  N N   . VAL A 1 257 ? 173.259 136.359 126.441 1.00 13.46  ? 258 VAL A N   1 
ATOM   2025  C CA  . VAL A 1 257 ? 173.162 137.524 127.312 1.00 9.89   ? 258 VAL A CA  1 
ATOM   2026  C C   . VAL A 1 257 ? 172.369 138.608 126.597 1.00 10.11  ? 258 VAL A C   1 
ATOM   2027  O O   . VAL A 1 257 ? 172.565 138.848 125.401 1.00 10.35  ? 258 VAL A O   1 
ATOM   2028  C CB  . VAL A 1 257 ? 174.554 138.054 127.722 1.00 8.19   ? 258 VAL A CB  1 
ATOM   2029  C CG1 . VAL A 1 257 ? 174.426 139.069 128.841 1.00 9.26   ? 258 VAL A CG1 1 
ATOM   2030  C CG2 . VAL A 1 257 ? 175.460 136.915 128.143 1.00 9.98   ? 258 VAL A CG2 1 
ATOM   2031  N N   . VAL A 1 258 ? 171.459 139.249 127.326 1.00 9.32   ? 259 VAL A N   1 
ATOM   2032  C CA  . VAL A 1 258 ? 170.754 140.439 126.862 1.00 8.56   ? 259 VAL A CA  1 
ATOM   2033  C C   . VAL A 1 258 ? 171.091 141.570 127.821 1.00 8.50   ? 259 VAL A C   1 
ATOM   2034  O O   . VAL A 1 258 ? 170.734 141.514 129.003 1.00 7.61   ? 259 VAL A O   1 
ATOM   2035  C CB  . VAL A 1 258 ? 169.235 140.220 126.783 1.00 8.49   ? 259 VAL A CB  1 
ATOM   2036  C CG1 . VAL A 1 258 ? 168.563 141.403 126.106 1.00 8.20   ? 259 VAL A CG1 1 
ATOM   2037  C CG2 . VAL A 1 258 ? 168.920 138.936 126.040 1.00 7.29   ? 259 VAL A CG2 1 
ATOM   2038  N N   . LEU A 1 259 ? 171.771 142.593 127.315 1.00 10.45  ? 260 LEU A N   1 
ATOM   2039  C CA  . LEU A 1 259 ? 172.230 143.715 128.123 1.00 9.15   ? 260 LEU A CA  1 
ATOM   2040  C C   . LEU A 1 259 ? 171.443 144.963 127.751 1.00 9.22   ? 260 LEU A C   1 
ATOM   2041  O O   . LEU A 1 259 ? 171.400 145.349 126.580 1.00 10.41  ? 260 LEU A O   1 
ATOM   2042  C CB  . LEU A 1 259 ? 173.731 143.947 127.928 1.00 10.03  ? 260 LEU A CB  1 
ATOM   2043  C CG  . LEU A 1 259 ? 174.392 145.131 128.637 1.00 9.01   ? 260 LEU A CG  1 
ATOM   2044  C CD1 . LEU A 1 259 ? 174.370 144.960 130.145 1.00 7.93   ? 260 LEU A CD1 1 
ATOM   2045  C CD2 . LEU A 1 259 ? 175.813 145.312 128.144 1.00 9.96   ? 260 LEU A CD2 1 
ATOM   2046  N N   . GLN A 1 260 ? 170.822 145.585 128.749 1.00 9.30   ? 261 GLN A N   1 
ATOM   2047  C CA  . GLN A 1 260 ? 170.043 146.804 128.567 1.00 9.55   ? 261 GLN A CA  1 
ATOM   2048  C C   . GLN A 1 260 ? 170.866 147.978 129.089 1.00 10.97  ? 261 GLN A C   1 
ATOM   2049  O O   . GLN A 1 260 ? 171.054 148.120 130.301 1.00 10.30  ? 261 GLN A O   1 
ATOM   2050  C CB  . GLN A 1 260 ? 168.704 146.696 129.291 1.00 9.79   ? 261 GLN A CB  1 
ATOM   2051  C CG  . GLN A 1 260 ? 167.581 147.489 128.661 1.00 10.16  ? 261 GLN A CG  1 
ATOM   2052  C CD  . GLN A 1 260 ? 167.197 148.694 129.485 1.00 10.54  ? 261 GLN A CD  1 
ATOM   2053  O OE1 . GLN A 1 260 ? 167.873 149.039 130.450 1.00 10.88  ? 261 GLN A OE1 1 
ATOM   2054  N NE2 . GLN A 1 260 ? 166.107 149.343 129.108 1.00 11.65  ? 261 GLN A NE2 1 
ATOM   2055  N N   . CYS A 1 261 ? 171.358 148.810 128.174 1.00 10.64  ? 262 CYS A N   1 
ATOM   2056  C CA  . CYS A 1 261 ? 172.261 149.907 128.520 1.00 9.95   ? 262 CYS A CA  1 
ATOM   2057  C C   . CYS A 1 261 ? 171.489 151.222 128.627 1.00 10.43  ? 262 CYS A C   1 
ATOM   2058  O O   . CYS A 1 261 ? 171.605 152.118 127.793 1.00 14.30  ? 262 CYS A O   1 
ATOM   2059  C CB  . CYS A 1 261 ? 173.386 150.005 127.495 1.00 11.24  ? 262 CYS A CB  1 
ATOM   2060  S SG  . CYS A 1 261 ? 173.965 148.423 126.853 1.00 17.23  ? 262 CYS A SG  1 
ATOM   2061  N N   . GLY A 1 262 ? 170.698 151.330 129.689 1.00 10.49  ? 263 GLY A N   1 
ATOM   2062  C CA  . GLY A 1 262 ? 169.987 152.570 129.946 1.00 9.26   ? 263 GLY A CA  1 
ATOM   2063  C C   . GLY A 1 262 ? 170.938 153.680 130.359 1.00 11.30  ? 263 GLY A C   1 
ATOM   2064  O O   . GLY A 1 262 ? 171.822 153.492 131.195 1.00 13.86  ? 263 GLY A O   1 
ATOM   2065  N N   . ALA A 1 263 ? 170.742 154.858 129.769 1.00 11.98  ? 264 ALA A N   1 
ATOM   2066  C CA  . ALA A 1 263 ? 171.664 155.975 129.924 1.00 10.03  ? 264 ALA A CA  1 
ATOM   2067  C C   . ALA A 1 263 ? 171.185 157.019 130.924 1.00 11.55  ? 264 ALA A C   1 
ATOM   2068  O O   . ALA A 1 263 ? 171.750 158.114 130.973 1.00 11.90  ? 264 ALA A O   1 
ATOM   2069  C CB  . ALA A 1 263 ? 171.922 156.635 128.569 1.00 7.57   ? 264 ALA A CB  1 
ATOM   2070  N N   . ASP A 1 264 ? 170.160 156.716 131.717 1.00 11.32  ? 265 ASP A N   1 
ATOM   2071  C CA  . ASP A 1 264 ? 169.714 157.647 132.746 1.00 12.50  ? 265 ASP A CA  1 
ATOM   2072  C C   . ASP A 1 264 ? 170.505 157.512 134.039 1.00 15.60  ? 265 ASP A C   1 
ATOM   2073  O O   . ASP A 1 264 ? 170.269 158.282 134.976 1.00 16.20  ? 265 ASP A O   1 
ATOM   2074  C CB  . ASP A 1 264 ? 168.221 157.463 133.025 1.00 13.08  ? 265 ASP A CB  1 
ATOM   2075  C CG  . ASP A 1 264 ? 167.793 156.019 132.975 1.00 13.81  ? 265 ASP A CG  1 
ATOM   2076  O OD1 . ASP A 1 264 ? 168.642 155.161 132.674 1.00 13.40  ? 265 ASP A OD1 1 
ATOM   2077  O OD2 . ASP A 1 264 ? 166.605 155.741 133.237 1.00 13.90  ? 265 ASP A OD2 1 
ATOM   2078  N N   . SER A 1 265 ? 171.434 156.564 134.110 1.00 15.91  ? 266 SER A N   1 
ATOM   2079  C CA  . SER A 1 265 ? 172.339 156.440 135.242 1.00 14.47  ? 266 SER A CA  1 
ATOM   2080  C C   . SER A 1 265 ? 173.594 157.287 135.082 1.00 16.27  ? 266 SER A C   1 
ATOM   2081  O O   . SER A 1 265 ? 174.487 157.214 135.930 1.00 16.27  ? 266 SER A O   1 
ATOM   2082  C CB  . SER A 1 265 ? 172.721 154.973 135.453 1.00 12.07  ? 266 SER A CB  1 
ATOM   2083  O OG  . SER A 1 265 ? 172.864 154.301 134.218 1.00 14.61  ? 266 SER A OG  1 
ATOM   2084  N N   . LEU A 1 266 ? 173.683 158.082 134.018 1.00 16.50  ? 267 LEU A N   1 
ATOM   2085  C CA  . LEU A 1 266 ? 174.791 159.000 133.824 1.00 16.07  ? 267 LEU A CA  1 
ATOM   2086  C C   . LEU A 1 266 ? 174.626 160.232 134.708 1.00 14.80  ? 267 LEU A C   1 
ATOM   2087  O O   . LEU A 1 266 ? 173.562 160.491 135.274 1.00 18.04  ? 267 LEU A O   1 
ATOM   2088  C CB  . LEU A 1 266 ? 174.893 159.420 132.360 1.00 15.77  ? 267 LEU A CB  1 
ATOM   2089  C CG  . LEU A 1 266 ? 175.335 158.382 131.331 1.00 12.18  ? 267 LEU A CG  1 
ATOM   2090  C CD1 . LEU A 1 266 ? 175.778 159.074 130.064 1.00 10.08  ? 267 LEU A CD1 1 
ATOM   2091  C CD2 . LEU A 1 266 ? 176.444 157.513 131.880 1.00 17.92  ? 267 LEU A CD2 1 
ATOM   2092  N N   . SER A 1 267 ? 175.703 161.002 134.818 1.00 15.36  ? 268 SER A N   1 
ATOM   2093  C CA  . SER A 1 267 ? 175.689 162.222 135.611 1.00 17.82  ? 268 SER A CA  1 
ATOM   2094  C C   . SER A 1 267 ? 175.061 163.364 134.823 1.00 19.58  ? 268 SER A C   1 
ATOM   2095  O O   . SER A 1 267 ? 175.309 163.524 133.626 1.00 20.54  ? 268 SER A O   1 
ATOM   2096  C CB  . SER A 1 267 ? 177.109 162.596 136.036 1.00 20.79  ? 268 SER A CB  1 
ATOM   2097  O OG  . SER A 1 267 ? 177.107 163.735 136.876 1.00 29.29  ? 268 SER A OG  1 
ATOM   2098  N N   . GLY A 1 268 ? 174.242 164.161 135.505 1.00 17.87  ? 269 GLY A N   1 
ATOM   2099  C CA  . GLY A 1 268 ? 173.595 165.288 134.868 1.00 15.93  ? 269 GLY A CA  1 
ATOM   2100  C C   . GLY A 1 268 ? 172.342 164.960 134.094 1.00 16.35  ? 269 GLY A C   1 
ATOM   2101  O O   . GLY A 1 268 ? 171.961 165.726 133.205 1.00 18.12  ? 269 GLY A O   1 
ATOM   2102  N N   . ASP A 1 269 ? 171.688 163.844 134.400 1.00 17.30  ? 270 ASP A N   1 
ATOM   2103  C CA  . ASP A 1 269 ? 170.479 163.457 133.694 1.00 16.51  ? 270 ASP A CA  1 
ATOM   2104  C C   . ASP A 1 269 ? 169.295 164.310 134.139 1.00 17.90  ? 270 ASP A C   1 
ATOM   2105  O O   . ASP A 1 269 ? 169.257 164.842 135.251 1.00 21.57  ? 270 ASP A O   1 
ATOM   2106  C CB  . ASP A 1 269 ? 170.170 161.979 133.923 1.00 16.15  ? 270 ASP A CB  1 
ATOM   2107  C CG  . ASP A 1 269 ? 169.400 161.361 132.777 1.00 17.91  ? 270 ASP A CG  1 
ATOM   2108  O OD1 . ASP A 1 269 ? 169.991 161.180 131.693 1.00 19.28  ? 270 ASP A OD1 1 
ATOM   2109  O OD2 . ASP A 1 269 ? 168.204 161.057 132.957 1.00 16.17  ? 270 ASP A OD2 1 
ATOM   2110  N N   . ARG A 1 270 ? 168.317 164.434 133.242 1.00 15.84  ? 271 ARG A N   1 
ATOM   2111  C CA  . ARG A 1 270 ? 167.105 165.185 133.536 1.00 15.42  ? 271 ARG A CA  1 
ATOM   2112  C C   . ARG A 1 270 ? 166.182 164.457 134.502 1.00 17.46  ? 271 ARG A C   1 
ATOM   2113  O O   . ARG A 1 270 ? 165.374 165.108 135.171 1.00 22.90  ? 271 ARG A O   1 
ATOM   2114  C CB  . ARG A 1 270 ? 166.351 165.487 132.242 1.00 16.17  ? 271 ARG A CB  1 
ATOM   2115  C CG  . ARG A 1 270 ? 165.797 166.889 132.161 1.00 17.17  ? 271 ARG A CG  1 
ATOM   2116  C CD  . ARG A 1 270 ? 165.436 167.251 130.737 1.00 16.82  ? 271 ARG A CD  1 
ATOM   2117  N NE  . ARG A 1 270 ? 166.612 167.597 129.951 1.00 19.59  ? 271 ARG A NE  1 
ATOM   2118  C CZ  . ARG A 1 270 ? 166.767 168.740 129.297 1.00 29.03  ? 271 ARG A CZ  1 
ATOM   2119  N NH1 . ARG A 1 270 ? 165.839 169.680 129.323 1.00 34.33  ? 271 ARG A NH1 1 
ATOM   2120  N NH2 . ARG A 1 270 ? 167.880 168.942 128.601 1.00 31.48  ? 271 ARG A NH2 1 
ATOM   2121  N N   . LEU A 1 271 ? 166.281 163.132 134.588 1.00 16.01  ? 272 LEU A N   1 
ATOM   2122  C CA  . LEU A 1 271 ? 165.419 162.341 135.459 1.00 14.98  ? 272 LEU A CA  1 
ATOM   2123  C C   . LEU A 1 271 ? 166.164 161.406 136.401 1.00 16.39  ? 272 LEU A C   1 
ATOM   2124  O O   . LEU A 1 271 ? 165.517 160.795 137.257 1.00 20.44  ? 272 LEU A O   1 
ATOM   2125  C CB  . LEU A 1 271 ? 164.434 161.509 134.625 1.00 17.20  ? 272 LEU A CB  1 
ATOM   2126  C CG  . LEU A 1 271 ? 163.020 162.049 134.404 1.00 17.09  ? 272 LEU A CG  1 
ATOM   2127  C CD1 . LEU A 1 271 ? 162.987 163.019 133.242 1.00 18.59  ? 272 LEU A CD1 1 
ATOM   2128  C CD2 . LEU A 1 271 ? 162.059 160.905 134.162 1.00 12.97  ? 272 LEU A CD2 1 
ATOM   2129  N N   . GLY A 1 272 ? 167.482 161.266 136.279 1.00 16.47  ? 273 GLY A N   1 
ATOM   2130  C CA  . GLY A 1 272 ? 168.219 160.367 137.138 1.00 17.69  ? 273 GLY A CA  1 
ATOM   2131  C C   . GLY A 1 272 ? 169.044 161.085 138.190 1.00 18.27  ? 273 GLY A C   1 
ATOM   2132  O O   . GLY A 1 272 ? 169.283 162.286 138.113 1.00 21.36  ? 273 GLY A O   1 
ATOM   2133  N N   . CYS A 1 273 ? 169.500 160.313 139.181 1.00 17.46  ? 274 CYS A N   1 
ATOM   2134  C CA  . CYS A 1 273 ? 170.210 160.852 140.335 1.00 17.01  ? 274 CYS A CA  1 
ATOM   2135  C C   . CYS A 1 273 ? 171.489 160.075 140.631 1.00 19.64  ? 274 CYS A C   1 
ATOM   2136  O O   . CYS A 1 273 ? 171.947 160.039 141.774 1.00 19.63  ? 274 CYS A O   1 
ATOM   2137  C CB  . CYS A 1 273 ? 169.303 160.873 141.565 1.00 20.74  ? 274 CYS A CB  1 
ATOM   2138  S SG  . CYS A 1 273 ? 168.847 159.243 142.192 1.00 29.01  ? 274 CYS A SG  1 
ATOM   2139  N N   . PHE A 1 274 ? 172.079 159.448 139.616 1.00 21.97  ? 275 PHE A N   1 
ATOM   2140  C CA  . PHE A 1 274 ? 173.360 158.781 139.772 1.00 16.80  ? 275 PHE A CA  1 
ATOM   2141  C C   . PHE A 1 274 ? 174.480 159.724 139.340 1.00 18.60  ? 275 PHE A C   1 
ATOM   2142  O O   . PHE A 1 274 ? 174.242 160.854 138.910 1.00 21.72  ? 275 PHE A O   1 
ATOM   2143  C CB  . PHE A 1 274 ? 173.389 157.476 138.978 1.00 15.57  ? 275 PHE A CB  1 
ATOM   2144  C CG  . PHE A 1 274 ? 172.773 156.310 139.701 1.00 16.84  ? 275 PHE A CG  1 
ATOM   2145  C CD1 . PHE A 1 274 ? 172.267 156.457 140.981 1.00 17.19  ? 275 PHE A CD1 1 
ATOM   2146  C CD2 . PHE A 1 274 ? 172.697 155.067 139.097 1.00 16.92  ? 275 PHE A CD2 1 
ATOM   2147  C CE1 . PHE A 1 274 ? 171.702 155.389 141.644 1.00 15.45  ? 275 PHE A CE1 1 
ATOM   2148  C CE2 . PHE A 1 274 ? 172.131 153.996 139.756 1.00 15.53  ? 275 PHE A CE2 1 
ATOM   2149  C CZ  . PHE A 1 274 ? 171.633 154.158 141.030 1.00 15.82  ? 275 PHE A CZ  1 
ATOM   2150  N N   . ASN A 1 275 ? 175.720 159.259 139.448 1.00 17.13  ? 276 ASN A N   1 
ATOM   2151  C CA  . ASN A 1 275 ? 176.890 160.087 139.181 1.00 17.65  ? 276 ASN A CA  1 
ATOM   2152  C C   . ASN A 1 275 ? 177.902 159.339 138.326 1.00 19.21  ? 276 ASN A C   1 
ATOM   2153  O O   . ASN A 1 275 ? 179.115 159.507 138.476 1.00 22.88  ? 276 ASN A O   1 
ATOM   2154  C CB  . ASN A 1 275 ? 177.526 160.560 140.485 1.00 20.84  ? 276 ASN A CB  1 
ATOM   2155  C CG  . ASN A 1 275 ? 178.280 161.861 140.330 1.00 23.27  ? 276 ASN A CG  1 
ATOM   2156  O OD1 . ASN A 1 275 ? 178.055 162.613 139.387 1.00 26.94  ? 276 ASN A OD1 1 
ATOM   2157  N ND2 . ASN A 1 275 ? 179.184 162.133 141.260 1.00 22.78  ? 276 ASN A ND2 1 
ATOM   2158  N N   . LEU A 1 276 ? 177.421 158.504 137.412 1.00 18.57  ? 277 LEU A N   1 
ATOM   2159  C CA  . LEU A 1 276 ? 178.308 157.777 136.521 1.00 18.63  ? 277 LEU A CA  1 
ATOM   2160  C C   . LEU A 1 276 ? 178.747 158.661 135.360 1.00 20.80  ? 277 LEU A C   1 
ATOM   2161  O O   . LEU A 1 276 ? 178.159 159.708 135.081 1.00 25.28  ? 277 LEU A O   1 
ATOM   2162  C CB  . LEU A 1 276 ? 177.629 156.519 135.980 1.00 18.02  ? 277 LEU A CB  1 
ATOM   2163  C CG  . LEU A 1 276 ? 177.205 155.437 136.971 1.00 16.74  ? 277 LEU A CG  1 
ATOM   2164  C CD1 . LEU A 1 276 ? 176.566 154.283 136.232 1.00 19.83  ? 277 LEU A CD1 1 
ATOM   2165  C CD2 . LEU A 1 276 ? 178.393 154.959 137.763 1.00 18.89  ? 277 LEU A CD2 1 
ATOM   2166  N N   . THR A 1 277 ? 179.797 158.223 134.680 1.00 20.91  ? 278 THR A N   1 
ATOM   2167  C CA  . THR A 1 277 ? 180.294 158.866 133.474 1.00 21.24  ? 278 THR A CA  1 
ATOM   2168  C C   . THR A 1 277 ? 180.131 157.911 132.297 1.00 22.44  ? 278 THR A C   1 
ATOM   2169  O O   . THR A 1 277 ? 179.571 156.821 132.424 1.00 24.65  ? 278 THR A O   1 
ATOM   2170  C CB  . THR A 1 277 ? 181.755 159.296 133.640 1.00 22.12  ? 278 THR A CB  1 
ATOM   2171  O OG1 . THR A 1 277 ? 182.523 158.204 134.157 1.00 21.07  ? 278 THR A OG1 1 
ATOM   2172  C CG2 . THR A 1 277 ? 181.860 160.471 134.592 1.00 24.63  ? 278 THR A CG2 1 
ATOM   2173  N N   . VAL A 1 278 ? 180.620 158.335 131.132 1.00 21.14  ? 279 VAL A N   1 
ATOM   2174  C CA  . VAL A 1 278 ? 180.521 157.497 129.943 1.00 20.15  ? 279 VAL A CA  1 
ATOM   2175  C C   . VAL A 1 278 ? 181.447 156.291 130.060 1.00 23.00  ? 279 VAL A C   1 
ATOM   2176  O O   . VAL A 1 278 ? 181.071 155.165 129.710 1.00 22.79  ? 279 VAL A O   1 
ATOM   2177  C CB  . VAL A 1 278 ? 180.816 158.334 128.685 1.00 20.73  ? 279 VAL A CB  1 
ATOM   2178  C CG1 . VAL A 1 278 ? 180.881 157.451 127.463 1.00 17.53  ? 279 VAL A CG1 1 
ATOM   2179  C CG2 . VAL A 1 278 ? 179.760 159.413 128.508 1.00 17.26  ? 279 VAL A CG2 1 
ATOM   2180  N N   . LYS A 1 279 ? 182.668 156.504 130.559 1.00 22.35  ? 280 LYS A N   1 
ATOM   2181  C CA  . LYS A 1 279 ? 183.606 155.401 130.742 1.00 21.37  ? 280 LYS A CA  1 
ATOM   2182  C C   . LYS A 1 279 ? 183.119 154.426 131.807 1.00 22.60  ? 280 LYS A C   1 
ATOM   2183  O O   . LYS A 1 279 ? 183.229 153.206 131.638 1.00 26.71  ? 280 LYS A O   1 
ATOM   2184  C CB  . LYS A 1 279 ? 184.986 155.946 131.104 1.00 26.63  ? 280 LYS A CB  1 
ATOM   2185  C CG  . LYS A 1 279 ? 185.692 156.654 129.963 1.00 27.40  ? 280 LYS A CG  1 
ATOM   2186  C CD  . LYS A 1 279 ? 187.187 156.392 129.995 1.00 29.65  ? 280 LYS A CD  1 
ATOM   2187  C CE  . LYS A 1 279 ? 187.948 157.430 129.186 1.00 35.36  ? 280 LYS A CE  1 
ATOM   2188  N NZ  . LYS A 1 279 ? 188.171 158.685 129.955 1.00 36.08  ? 280 LYS A NZ  1 
ATOM   2189  N N   . GLY A 1 280 ? 182.575 154.943 132.910 1.00 22.61  ? 281 GLY A N   1 
ATOM   2190  C CA  . GLY A 1 280 ? 182.017 154.076 133.930 1.00 22.28  ? 281 GLY A CA  1 
ATOM   2191  C C   . GLY A 1 280 ? 180.760 153.359 133.497 1.00 20.68  ? 281 GLY A C   1 
ATOM   2192  O O   . GLY A 1 280 ? 180.434 152.309 134.057 1.00 22.10  ? 281 GLY A O   1 
ATOM   2193  N N   . HIS A 1 281 ? 180.039 153.913 132.521 1.00 21.71  ? 282 HIS A N   1 
ATOM   2194  C CA  . HIS A 1 281 ? 178.901 153.212 131.937 1.00 20.31  ? 282 HIS A CA  1 
ATOM   2195  C C   . HIS A 1 281 ? 179.359 152.094 131.010 1.00 19.72  ? 282 HIS A C   1 
ATOM   2196  O O   . HIS A 1 281 ? 178.807 150.989 131.042 1.00 18.85  ? 282 HIS A O   1 
ATOM   2197  C CB  . HIS A 1 281 ? 178.016 154.207 131.185 1.00 21.42  ? 282 HIS A CB  1 
ATOM   2198  C CG  . HIS A 1 281 ? 176.567 153.832 131.149 1.00 22.51  ? 282 HIS A CG  1 
ATOM   2199  N ND1 . HIS A 1 281 ? 176.007 153.126 130.106 1.00 19.24  ? 282 HIS A ND1 1 
ATOM   2200  C CD2 . HIS A 1 281 ? 175.560 154.082 132.017 1.00 20.04  ? 282 HIS A CD2 1 
ATOM   2201  C CE1 . HIS A 1 281 ? 174.720 152.948 130.339 1.00 14.16  ? 282 HIS A CE1 1 
ATOM   2202  N NE2 . HIS A 1 281 ? 174.423 153.519 131.492 1.00 15.45  ? 282 HIS A NE2 1 
ATOM   2203  N N   . ALA A 1 282 ? 180.369 152.358 130.180 1.00 23.31  ? 283 ALA A N   1 
ATOM   2204  C CA  . ALA A 1 282 ? 180.850 151.368 129.224 1.00 20.10  ? 283 ALA A CA  1 
ATOM   2205  C C   . ALA A 1 282 ? 181.753 150.316 129.852 1.00 20.62  ? 283 ALA A C   1 
ATOM   2206  O O   . ALA A 1 282 ? 182.063 149.315 129.194 1.00 22.88  ? 283 ALA A O   1 
ATOM   2207  C CB  . ALA A 1 282 ? 181.590 152.057 128.079 1.00 17.58  ? 283 ALA A CB  1 
ATOM   2208  N N   . LYS A 1 283 ? 182.197 150.520 131.093 1.00 21.68  ? 284 LYS A N   1 
ATOM   2209  C CA  . LYS A 1 283 ? 182.912 149.455 131.786 1.00 23.49  ? 284 LYS A CA  1 
ATOM   2210  C C   . LYS A 1 283 ? 182.041 148.217 131.954 1.00 22.27  ? 284 LYS A C   1 
ATOM   2211  O O   . LYS A 1 283 ? 182.552 147.094 131.943 1.00 22.89  ? 284 LYS A O   1 
ATOM   2212  C CB  . LYS A 1 283 ? 183.407 149.947 133.143 1.00 21.75  ? 284 LYS A CB  1 
ATOM   2213  C CG  . LYS A 1 283 ? 184.427 149.032 133.791 1.00 27.66  ? 284 LYS A CG  1 
ATOM   2214  C CD  . LYS A 1 283 ? 185.841 149.513 133.536 1.00 30.72  ? 284 LYS A CD  1 
ATOM   2215  C CE  . LYS A 1 283 ? 186.808 148.344 133.460 1.00 36.32  ? 284 LYS A CE  1 
ATOM   2216  N NZ  . LYS A 1 283 ? 186.480 147.425 132.337 1.00 34.14  ? 284 LYS A NZ  1 
ATOM   2217  N N   . CYS A 1 284 ? 180.726 148.399 132.100 1.00 21.49  ? 285 CYS A N   1 
ATOM   2218  C CA  . CYS A 1 284 ? 179.820 147.257 132.166 1.00 16.93  ? 285 CYS A CA  1 
ATOM   2219  C C   . CYS A 1 284 ? 179.836 146.463 130.866 1.00 17.54  ? 285 CYS A C   1 
ATOM   2220  O O   . CYS A 1 284 ? 179.862 145.227 130.881 1.00 19.16  ? 285 CYS A O   1 
ATOM   2221  C CB  . CYS A 1 284 ? 178.404 147.734 132.486 1.00 15.12  ? 285 CYS A CB  1 
ATOM   2222  S SG  . CYS A 1 284 ? 178.298 148.888 133.868 1.00 16.90  ? 285 CYS A SG  1 
ATOM   2223  N N   . VAL A 1 285 ? 179.822 147.160 129.728 1.00 19.50  ? 286 VAL A N   1 
ATOM   2224  C CA  . VAL A 1 285 ? 179.896 146.491 128.433 1.00 17.55  ? 286 VAL A CA  1 
ATOM   2225  C C   . VAL A 1 285 ? 181.234 145.784 128.276 1.00 18.83  ? 286 VAL A C   1 
ATOM   2226  O O   . VAL A 1 285 ? 181.309 144.675 127.734 1.00 19.17  ? 286 VAL A O   1 
ATOM   2227  C CB  . VAL A 1 285 ? 179.654 147.503 127.297 1.00 19.03  ? 286 VAL A CB  1 
ATOM   2228  C CG1 . VAL A 1 285 ? 179.607 146.798 125.954 1.00 19.41  ? 286 VAL A CG1 1 
ATOM   2229  C CG2 . VAL A 1 285 ? 178.375 148.281 127.545 1.00 19.46  ? 286 VAL A CG2 1 
ATOM   2230  N N   . GLU A 1 286 ? 182.314 146.420 128.736 1.00 22.48  ? 287 GLU A N   1 
ATOM   2231  C CA  . GLU A 1 286 ? 183.629 145.788 128.662 1.00 22.63  ? 287 GLU A CA  1 
ATOM   2232  C C   . GLU A 1 286 ? 183.680 144.516 129.500 1.00 22.36  ? 287 GLU A C   1 
ATOM   2233  O O   . GLU A 1 286 ? 184.259 143.509 129.078 1.00 23.79  ? 287 GLU A O   1 
ATOM   2234  C CB  . GLU A 1 286 ? 184.711 146.767 129.116 1.00 22.48  ? 287 GLU A CB  1 
ATOM   2235  C CG  . GLU A 1 286 ? 184.881 147.976 128.216 1.00 28.66  ? 287 GLU A CG  1 
ATOM   2236  C CD  . GLU A 1 286 ? 185.845 148.996 128.787 1.00 39.62  ? 287 GLU A CD  1 
ATOM   2237  O OE1 . GLU A 1 286 ? 186.735 148.600 129.568 1.00 45.93  ? 287 GLU A OE1 1 
ATOM   2238  O OE2 . GLU A 1 286 ? 185.714 150.193 128.456 1.00 35.51  ? 287 GLU A OE2 1 
ATOM   2239  N N   . VAL A 1 287 ? 183.087 144.545 130.695 1.00 22.88  ? 288 VAL A N   1 
ATOM   2240  C CA  . VAL A 1 287 ? 183.105 143.381 131.576 1.00 20.82  ? 288 VAL A CA  1 
ATOM   2241  C C   . VAL A 1 287 ? 182.254 142.254 131.002 1.00 19.60  ? 288 VAL A C   1 
ATOM   2242  O O   . VAL A 1 287 ? 182.657 141.085 131.018 1.00 21.11  ? 288 VAL A O   1 
ATOM   2243  C CB  . VAL A 1 287 ? 182.642 143.781 132.989 1.00 19.96  ? 288 VAL A CB  1 
ATOM   2244  C CG1 . VAL A 1 287 ? 182.280 142.552 133.808 1.00 20.36  ? 288 VAL A CG1 1 
ATOM   2245  C CG2 . VAL A 1 287 ? 183.717 144.592 133.684 1.00 20.96  ? 288 VAL A CG2 1 
ATOM   2246  N N   . VAL A 1 288 ? 181.067 142.581 130.486 1.00 19.46  ? 289 VAL A N   1 
ATOM   2247  C CA  . VAL A 1 288 ? 180.183 141.551 129.943 1.00 18.81  ? 289 VAL A CA  1 
ATOM   2248  C C   . VAL A 1 288 ? 180.817 140.887 128.726 1.00 20.55  ? 289 VAL A C   1 
ATOM   2249  O O   . VAL A 1 288 ? 180.668 139.679 128.510 1.00 23.18  ? 289 VAL A O   1 
ATOM   2250  C CB  . VAL A 1 288 ? 178.805 142.156 129.611 1.00 14.95  ? 289 VAL A CB  1 
ATOM   2251  C CG1 . VAL A 1 288 ? 177.969 141.182 128.810 1.00 11.24  ? 289 VAL A CG1 1 
ATOM   2252  C CG2 . VAL A 1 288 ? 178.080 142.546 130.884 1.00 12.88  ? 289 VAL A CG2 1 
ATOM   2253  N N   . LYS A 1 289 ? 181.547 141.661 127.925 1.00 21.85  ? 290 LYS A N   1 
ATOM   2254  C CA  . LYS A 1 289 ? 182.125 141.166 126.681 1.00 22.24  ? 290 LYS A CA  1 
ATOM   2255  C C   . LYS A 1 289 ? 183.242 140.150 126.891 1.00 25.27  ? 290 LYS A C   1 
ATOM   2256  O O   . LYS A 1 289 ? 183.633 139.488 125.925 1.00 28.97  ? 290 LYS A O   1 
ATOM   2257  C CB  . LYS A 1 289 ? 182.654 142.343 125.863 1.00 24.72  ? 290 LYS A CB  1 
ATOM   2258  C CG  . LYS A 1 289 ? 182.221 142.350 124.413 1.00 24.27  ? 290 LYS A CG  1 
ATOM   2259  C CD  . LYS A 1 289 ? 182.638 143.640 123.735 1.00 25.88  ? 290 LYS A CD  1 
ATOM   2260  C CE  . LYS A 1 289 ? 184.107 143.614 123.361 1.00 29.90  ? 290 LYS A CE  1 
ATOM   2261  N NZ  . LYS A 1 289 ? 184.330 142.926 122.062 1.00 33.02  ? 290 LYS A NZ  1 
ATOM   2262  N N   . THR A 1 290 ? 183.764 140.009 128.110 1.00 25.12  ? 291 THR A N   1 
ATOM   2263  C CA  . THR A 1 290 ? 184.895 139.120 128.352 1.00 25.12  ? 291 THR A CA  1 
ATOM   2264  C C   . THR A 1 290 ? 184.499 137.658 128.485 1.00 28.08  ? 291 THR A C   1 
ATOM   2265  O O   . THR A 1 290 ? 185.385 136.801 128.557 1.00 32.02  ? 291 THR A O   1 
ATOM   2266  C CB  . THR A 1 290 ? 185.651 139.543 129.615 1.00 25.67  ? 291 THR A CB  1 
ATOM   2267  O OG1 . THR A 1 290 ? 184.783 139.452 130.751 1.00 22.83  ? 291 THR A OG1 1 
ATOM   2268  C CG2 . THR A 1 290 ? 186.162 140.965 129.485 1.00 26.29  ? 291 THR A CG2 1 
ATOM   2269  N N   . PHE A 1 291 ? 183.207 137.347 128.525 1.00 27.10  ? 292 PHE A N   1 
ATOM   2270  C CA  . PHE A 1 291 ? 182.751 135.979 128.720 1.00 23.78  ? 292 PHE A CA  1 
ATOM   2271  C C   . PHE A 1 291 ? 182.496 135.240 127.413 1.00 26.72  ? 292 PHE A C   1 
ATOM   2272  O O   . PHE A 1 291 ? 182.223 134.037 127.448 1.00 30.51  ? 292 PHE A O   1 
ATOM   2273  C CB  . PHE A 1 291 ? 181.490 135.972 129.586 1.00 20.96  ? 292 PHE A CB  1 
ATOM   2274  C CG  . PHE A 1 291 ? 181.724 136.457 130.985 1.00 24.32  ? 292 PHE A CG  1 
ATOM   2275  C CD1 . PHE A 1 291 ? 182.369 135.656 131.909 1.00 24.19  ? 292 PHE A CD1 1 
ATOM   2276  C CD2 . PHE A 1 291 ? 181.313 137.719 131.374 1.00 26.10  ? 292 PHE A CD2 1 
ATOM   2277  C CE1 . PHE A 1 291 ? 182.594 136.101 133.195 1.00 23.09  ? 292 PHE A CE1 1 
ATOM   2278  C CE2 . PHE A 1 291 ? 181.535 138.169 132.661 1.00 25.26  ? 292 PHE A CE2 1 
ATOM   2279  C CZ  . PHE A 1 291 ? 182.176 137.358 133.570 1.00 25.20  ? 292 PHE A CZ  1 
ATOM   2280  N N   . ASN A 1 292 ? 182.587 135.927 126.273 1.00 25.33  ? 293 ASN A N   1 
ATOM   2281  C CA  . ASN A 1 292 ? 182.491 135.307 124.949 1.00 26.13  ? 293 ASN A CA  1 
ATOM   2282  C C   . ASN A 1 292 ? 181.177 134.544 124.770 1.00 24.30  ? 293 ASN A C   1 
ATOM   2283  O O   . ASN A 1 292 ? 181.153 133.397 124.320 1.00 24.35  ? 293 ASN A O   1 
ATOM   2284  C CB  . ASN A 1 292 ? 183.693 134.399 124.684 1.00 29.15  ? 293 ASN A CB  1 
ATOM   2285  C CG  . ASN A 1 292 ? 185.006 135.155 124.691 1.00 32.63  ? 293 ASN A CG  1 
ATOM   2286  O OD1 . ASN A 1 292 ? 185.071 136.313 124.280 1.00 33.05  ? 293 ASN A OD1 1 
ATOM   2287  N ND2 . ASN A 1 292 ? 186.061 134.502 125.160 1.00 31.24  ? 293 ASN A ND2 1 
ATOM   2288  N N   . LEU A 1 293 ? 180.079 135.195 125.123 1.00 22.05  ? 294 LEU A N   1 
ATOM   2289  C CA  . LEU A 1 293 ? 178.738 134.686 124.894 1.00 21.32  ? 294 LEU A CA  1 
ATOM   2290  C C   . LEU A 1 293 ? 178.010 135.564 123.886 1.00 21.84  ? 294 LEU A C   1 
ATOM   2291  O O   . LEU A 1 293 ? 178.355 136.738 123.711 1.00 28.44  ? 294 LEU A O   1 
ATOM   2292  C CB  . LEU A 1 293 ? 177.936 134.640 126.202 1.00 20.38  ? 294 LEU A CB  1 
ATOM   2293  C CG  . LEU A 1 293 ? 178.393 133.679 127.299 1.00 16.62  ? 294 LEU A CG  1 
ATOM   2294  C CD1 . LEU A 1 293 ? 177.730 134.029 128.612 1.00 14.04  ? 294 LEU A CD1 1 
ATOM   2295  C CD2 . LEU A 1 293 ? 178.080 132.249 126.913 1.00 18.64  ? 294 LEU A CD2 1 
ATOM   2296  N N   . PRO A 1 294 ? 177.016 135.025 123.180 1.00 19.42  ? 295 PRO A N   1 
ATOM   2297  C CA  . PRO A 1 294 ? 176.190 135.875 122.314 1.00 16.06  ? 295 PRO A CA  1 
ATOM   2298  C C   . PRO A 1 294 ? 175.562 137.011 123.108 1.00 14.67  ? 295 PRO A C   1 
ATOM   2299  O O   . PRO A 1 294 ? 175.031 136.808 124.200 1.00 16.41  ? 295 PRO A O   1 
ATOM   2300  C CB  . PRO A 1 294 ? 175.134 134.906 121.773 1.00 13.19  ? 295 PRO A CB  1 
ATOM   2301  C CG  . PRO A 1 294 ? 175.803 133.583 121.800 1.00 16.28  ? 295 PRO A CG  1 
ATOM   2302  C CD  . PRO A 1 294 ? 176.735 133.593 122.979 1.00 17.83  ? 295 PRO A CD  1 
ATOM   2303  N N   . LEU A 1 295 ? 175.625 138.216 122.547 1.00 13.20  ? 296 LEU A N   1 
ATOM   2304  C CA  . LEU A 1 295 ? 175.228 139.424 123.253 1.00 11.93  ? 296 LEU A CA  1 
ATOM   2305  C C   . LEU A 1 295 ? 174.254 140.230 122.408 1.00 11.83  ? 296 LEU A C   1 
ATOM   2306  O O   . LEU A 1 295 ? 174.429 140.359 121.194 1.00 12.74  ? 296 LEU A O   1 
ATOM   2307  C CB  . LEU A 1 295 ? 176.453 140.279 123.607 1.00 11.59  ? 296 LEU A CB  1 
ATOM   2308  C CG  . LEU A 1 295 ? 176.243 141.491 124.516 1.00 11.05  ? 296 LEU A CG  1 
ATOM   2309  C CD1 . LEU A 1 295 ? 175.546 141.096 125.801 1.00 8.46   ? 296 LEU A CD1 1 
ATOM   2310  C CD2 . LEU A 1 295 ? 177.571 142.158 124.816 1.00 12.69  ? 296 LEU A CD2 1 
ATOM   2311  N N   . LEU A 1 296 ? 173.226 140.768 123.062 1.00 11.76  ? 297 LEU A N   1 
ATOM   2312  C CA  . LEU A 1 296 ? 172.235 141.637 122.436 1.00 9.63   ? 297 LEU A CA  1 
ATOM   2313  C C   . LEU A 1 296 ? 172.195 142.936 123.230 1.00 9.37   ? 297 LEU A C   1 
ATOM   2314  O O   . LEU A 1 296 ? 171.700 142.960 124.361 1.00 8.29   ? 297 LEU A O   1 
ATOM   2315  C CB  . LEU A 1 296 ? 170.866 140.960 122.394 1.00 9.25   ? 297 LEU A CB  1 
ATOM   2316  C CG  . LEU A 1 296 ? 169.665 141.714 121.819 1.00 11.21  ? 297 LEU A CG  1 
ATOM   2317  C CD1 . LEU A 1 296 ? 169.953 142.250 120.428 1.00 13.27  ? 297 LEU A CD1 1 
ATOM   2318  C CD2 . LEU A 1 296 ? 168.448 140.811 121.800 1.00 7.93   ? 297 LEU A CD2 1 
ATOM   2319  N N   . MET A 1 297 ? 172.716 144.009 122.640 1.00 9.38   ? 298 MET A N   1 
ATOM   2320  C CA  . MET A 1 297 ? 172.852 145.296 123.312 1.00 9.93   ? 298 MET A CA  1 
ATOM   2321  C C   . MET A 1 297 ? 171.693 146.200 122.917 1.00 8.84   ? 298 MET A C   1 
ATOM   2322  O O   . MET A 1 297 ? 171.579 146.597 121.754 1.00 9.53   ? 298 MET A O   1 
ATOM   2323  C CB  . MET A 1 297 ? 174.185 145.954 122.960 1.00 12.78  ? 298 MET A CB  1 
ATOM   2324  C CG  . MET A 1 297 ? 175.317 145.630 123.911 1.00 12.43  ? 298 MET A CG  1 
ATOM   2325  S SD  . MET A 1 297 ? 176.472 147.000 124.096 1.00 30.45  ? 298 MET A SD  1 
ATOM   2326  C CE  . MET A 1 297 ? 176.438 147.706 122.453 1.00 14.43  ? 298 MET A CE  1 
ATOM   2327  N N   . LEU A 1 298 ? 170.853 146.540 123.889 1.00 9.20   ? 299 LEU A N   1 
ATOM   2328  C CA  . LEU A 1 298 ? 169.645 147.314 123.663 1.00 8.94   ? 299 LEU A CA  1 
ATOM   2329  C C   . LEU A 1 298 ? 169.728 148.641 124.405 1.00 11.25  ? 299 LEU A C   1 
ATOM   2330  O O   . LEU A 1 298 ? 170.550 148.822 125.306 1.00 13.66  ? 299 LEU A O   1 
ATOM   2331  C CB  . LEU A 1 298 ? 168.404 146.534 124.111 1.00 8.12   ? 299 LEU A CB  1 
ATOM   2332  C CG  . LEU A 1 298 ? 168.200 145.171 123.449 1.00 7.64   ? 299 LEU A CG  1 
ATOM   2333  C CD1 . LEU A 1 298 ? 167.032 144.443 124.080 1.00 10.61  ? 299 LEU A CD1 1 
ATOM   2334  C CD2 . LEU A 1 298 ? 167.999 145.320 121.953 1.00 8.44   ? 299 LEU A CD2 1 
ATOM   2335  N N   . GLY A 1 299 ? 168.861 149.571 124.019 1.00 9.50   ? 300 GLY A N   1 
ATOM   2336  C CA  . GLY A 1 299 ? 168.870 150.897 124.603 1.00 9.24   ? 300 GLY A CA  1 
ATOM   2337  C C   . GLY A 1 299 ? 168.166 150.954 125.940 1.00 10.69  ? 300 GLY A C   1 
ATOM   2338  O O   . GLY A 1 299 ? 168.356 150.072 126.778 1.00 12.33  ? 300 GLY A O   1 
ATOM   2339  N N   . GLY A 1 300 ? 167.354 151.982 126.159 1.00 10.66  ? 301 GLY A N   1 
ATOM   2340  C CA  . GLY A 1 300 ? 166.641 152.105 127.413 1.00 11.87  ? 301 GLY A CA  1 
ATOM   2341  C C   . GLY A 1 300 ? 166.223 153.522 127.738 1.00 15.22  ? 301 GLY A C   1 
ATOM   2342  O O   . GLY A 1 300 ? 165.596 154.195 126.917 1.00 16.81  ? 301 GLY A O   1 
ATOM   2343  N N   . GLY A 1 301 ? 166.561 153.983 128.936 1.00 10.13  ? 302 GLY A N   1 
ATOM   2344  C CA  . GLY A 1 301 ? 166.257 155.335 129.351 1.00 8.62   ? 302 GLY A CA  1 
ATOM   2345  C C   . GLY A 1 301 ? 167.279 156.324 128.835 1.00 11.21  ? 302 GLY A C   1 
ATOM   2346  O O   . GLY A 1 301 ? 168.025 156.060 127.889 1.00 16.89  ? 302 GLY A O   1 
ATOM   2347  N N   . GLY A 1 302 ? 167.309 157.488 129.473 1.00 10.37  ? 303 GLY A N   1 
ATOM   2348  C CA  . GLY A 1 302 ? 168.226 158.536 129.077 1.00 10.60  ? 303 GLY A CA  1 
ATOM   2349  C C   . GLY A 1 302 ? 167.506 159.765 128.574 1.00 13.41  ? 303 GLY A C   1 
ATOM   2350  O O   . GLY A 1 302 ? 166.934 159.752 127.481 1.00 14.09  ? 303 GLY A O   1 
ATOM   2351  N N   . TYR A 1 303 ? 167.533 160.841 129.359 1.00 16.60  ? 304 TYR A N   1 
ATOM   2352  C CA  . TYR A 1 303 ? 166.690 161.999 129.106 1.00 14.64  ? 304 TYR A CA  1 
ATOM   2353  C C   . TYR A 1 303 ? 167.465 163.299 128.948 1.00 15.63  ? 304 TYR A C   1 
ATOM   2354  O O   . TYR A 1 303 ? 166.846 164.343 128.717 1.00 20.38  ? 304 TYR A O   1 
ATOM   2355  C CB  . TYR A 1 303 ? 165.642 162.117 130.219 1.00 11.14  ? 304 TYR A CB  1 
ATOM   2356  C CG  . TYR A 1 303 ? 164.931 160.800 130.434 1.00 12.24  ? 304 TYR A CG  1 
ATOM   2357  C CD1 . TYR A 1 303 ? 164.001 160.335 129.513 1.00 11.80  ? 304 TYR A CD1 1 
ATOM   2358  C CD2 . TYR A 1 303 ? 165.230 159.996 131.523 1.00 13.22  ? 304 TYR A CD2 1 
ATOM   2359  C CE1 . TYR A 1 303 ? 163.366 159.124 129.690 1.00 9.15   ? 304 TYR A CE1 1 
ATOM   2360  C CE2 . TYR A 1 303 ? 164.599 158.782 131.708 1.00 12.76  ? 304 TYR A CE2 1 
ATOM   2361  C CZ  . TYR A 1 303 ? 163.670 158.352 130.787 1.00 12.65  ? 304 TYR A CZ  1 
ATOM   2362  O OH  . TYR A 1 303 ? 163.039 157.145 130.966 1.00 15.30  ? 304 TYR A OH  1 
ATOM   2363  N N   . THR A 1 304 ? 168.790 163.269 129.058 1.00 15.36  ? 305 THR A N   1 
ATOM   2364  C CA  . THR A 1 304 ? 169.650 164.324 128.529 1.00 18.27  ? 305 THR A CA  1 
ATOM   2365  C C   . THR A 1 304 ? 170.251 163.786 127.235 1.00 19.44  ? 305 THR A C   1 
ATOM   2366  O O   . THR A 1 304 ? 171.116 162.906 127.263 1.00 19.48  ? 305 THR A O   1 
ATOM   2367  C CB  . THR A 1 304 ? 170.733 164.724 129.526 1.00 18.78  ? 305 THR A CB  1 
ATOM   2368  O OG1 . THR A 1 304 ? 170.125 165.291 130.692 1.00 20.61  ? 305 THR A OG1 1 
ATOM   2369  C CG2 . THR A 1 304 ? 171.657 165.751 128.907 1.00 20.17  ? 305 THR A CG2 1 
ATOM   2370  N N   . ILE A 1 305 ? 169.793 164.324 126.105 1.00 17.96  ? 306 ILE A N   1 
ATOM   2371  C CA  . ILE A 1 305 ? 169.902 163.617 124.831 1.00 16.39  ? 306 ILE A CA  1 
ATOM   2372  C C   . ILE A 1 305 ? 171.351 163.550 124.353 1.00 17.17  ? 306 ILE A C   1 
ATOM   2373  O O   . ILE A 1 305 ? 171.791 162.529 123.807 1.00 16.85  ? 306 ILE A O   1 
ATOM   2374  C CB  . ILE A 1 305 ? 168.977 164.282 123.795 1.00 20.32  ? 306 ILE A CB  1 
ATOM   2375  C CG1 . ILE A 1 305 ? 167.512 163.973 124.108 1.00 17.33  ? 306 ILE A CG1 1 
ATOM   2376  C CG2 . ILE A 1 305 ? 169.291 163.803 122.405 1.00 23.52  ? 306 ILE A CG2 1 
ATOM   2377  C CD1 . ILE A 1 305 ? 167.281 162.631 124.767 1.00 14.79  ? 306 ILE A CD1 1 
ATOM   2378  N N   . ARG A 1 306 ? 172.115 164.629 124.543 1.00 18.05  ? 307 ARG A N   1 
ATOM   2379  C CA  . ARG A 1 306 ? 173.511 164.628 124.112 1.00 17.84  ? 307 ARG A CA  1 
ATOM   2380  C C   . ARG A 1 306 ? 174.331 163.606 124.893 1.00 17.53  ? 307 ARG A C   1 
ATOM   2381  O O   . ARG A 1 306 ? 175.200 162.930 124.327 1.00 17.80  ? 307 ARG A O   1 
ATOM   2382  C CB  . ARG A 1 306 ? 174.104 166.031 124.250 1.00 18.73  ? 307 ARG A CB  1 
ATOM   2383  C CG  . ARG A 1 306 ? 174.166 166.552 125.674 1.00 22.98  ? 307 ARG A CG  1 
ATOM   2384  C CD  . ARG A 1 306 ? 174.197 168.064 125.727 1.00 25.34  ? 307 ARG A CD  1 
ATOM   2385  N NE  . ARG A 1 306 ? 174.079 168.550 127.095 1.00 29.25  ? 307 ARG A NE  1 
ATOM   2386  C CZ  . ARG A 1 306 ? 173.042 169.231 127.562 1.00 37.65  ? 307 ARG A CZ  1 
ATOM   2387  N NH1 . ARG A 1 306 ? 172.011 169.534 126.791 1.00 40.85  ? 307 ARG A NH1 1 
ATOM   2388  N NH2 . ARG A 1 306 ? 173.038 169.616 128.835 1.00 38.14  ? 307 ARG A NH2 1 
ATOM   2389  N N   . ASN A 1 307 ? 174.061 163.470 126.193 1.00 16.77  ? 308 ASN A N   1 
ATOM   2390  C CA  . ASN A 1 307 ? 174.744 162.459 126.991 1.00 15.45  ? 308 ASN A CA  1 
ATOM   2391  C C   . ASN A 1 307 ? 174.387 161.057 126.521 1.00 12.42  ? 308 ASN A C   1 
ATOM   2392  O O   . ASN A 1 307 ? 175.242 160.166 126.501 1.00 13.63  ? 308 ASN A O   1 
ATOM   2393  C CB  . ASN A 1 307 ? 174.396 162.631 128.468 1.00 19.26  ? 308 ASN A CB  1 
ATOM   2394  C CG  . ASN A 1 307 ? 174.993 163.887 129.068 1.00 17.79  ? 308 ASN A CG  1 
ATOM   2395  O OD1 . ASN A 1 307 ? 175.693 164.640 128.396 1.00 17.00  ? 308 ASN A OD1 1 
ATOM   2396  N ND2 . ASN A 1 307 ? 174.720 164.115 130.345 1.00 18.35  ? 308 ASN A ND2 1 
ATOM   2397  N N   . VAL A 1 308 ? 173.126 160.842 126.140 1.00 14.42  ? 309 VAL A N   1 
ATOM   2398  C CA  . VAL A 1 308 ? 172.706 159.545 125.613 1.00 13.37  ? 309 VAL A CA  1 
ATOM   2399  C C   . VAL A 1 308 ? 173.461 159.226 124.330 1.00 11.18  ? 309 VAL A C   1 
ATOM   2400  O O   . VAL A 1 308 ? 173.946 158.105 124.133 1.00 11.99  ? 309 VAL A O   1 
ATOM   2401  C CB  . VAL A 1 308 ? 171.185 159.530 125.385 1.00 12.15  ? 309 VAL A CB  1 
ATOM   2402  C CG1 . VAL A 1 308 ? 170.746 158.200 124.825 1.00 11.09  ? 309 VAL A CG1 1 
ATOM   2403  C CG2 . VAL A 1 308 ? 170.461 159.825 126.673 1.00 13.95  ? 309 VAL A CG2 1 
ATOM   2404  N N   . ALA A 1 309 ? 173.568 160.213 123.437 1.00 13.16  ? 310 ALA A N   1 
ATOM   2405  C CA  . ALA A 1 309 ? 174.289 160.010 122.186 1.00 10.10  ? 310 ALA A CA  1 
ATOM   2406  C C   . ALA A 1 309 ? 175.750 159.666 122.445 1.00 10.85  ? 310 ALA A C   1 
ATOM   2407  O O   . ALA A 1 309 ? 176.293 158.728 121.850 1.00 10.47  ? 310 ALA A O   1 
ATOM   2408  C CB  . ALA A 1 309 ? 174.174 161.256 121.310 1.00 11.04  ? 310 ALA A CB  1 
ATOM   2409  N N   . ARG A 1 310 ? 176.396 160.405 123.351 1.00 15.44  ? 311 ARG A N   1 
ATOM   2410  C CA  . ARG A 1 310 ? 177.800 160.143 123.663 1.00 12.62  ? 311 ARG A CA  1 
ATOM   2411  C C   . ARG A 1 310 ? 177.986 158.754 124.262 1.00 11.27  ? 311 ARG A C   1 
ATOM   2412  O O   . ARG A 1 310 ? 178.890 158.006 123.866 1.00 14.60  ? 311 ARG A O   1 
ATOM   2413  C CB  . ARG A 1 310 ? 178.329 161.206 124.623 1.00 14.51  ? 311 ARG A CB  1 
ATOM   2414  C CG  . ARG A 1 310 ? 178.419 162.600 124.044 1.00 17.71  ? 311 ARG A CG  1 
ATOM   2415  C CD  . ARG A 1 310 ? 178.524 163.628 125.156 1.00 21.79  ? 311 ARG A CD  1 
ATOM   2416  N NE  . ARG A 1 310 ? 179.091 164.886 124.688 1.00 27.93  ? 311 ARG A NE  1 
ATOM   2417  C CZ  . ARG A 1 310 ? 178.760 166.079 125.160 1.00 27.63  ? 311 ARG A CZ  1 
ATOM   2418  N NH1 . ARG A 1 310 ? 177.857 166.217 126.115 1.00 24.00  ? 311 ARG A NH1 1 
ATOM   2419  N NH2 . ARG A 1 310 ? 179.348 167.160 124.661 1.00 35.05  ? 311 ARG A NH2 1 
ATOM   2420  N N   . CYS A 1 311 ? 177.131 158.390 125.220 1.00 10.17  ? 312 CYS A N   1 
ATOM   2421  C CA  . CYS A 1 311 ? 177.263 157.105 125.894 1.00 10.23  ? 312 CYS A CA  1 
ATOM   2422  C C   . CYS A 1 311 ? 177.074 155.953 124.920 1.00 12.76  ? 312 CYS A C   1 
ATOM   2423  O O   . CYS A 1 311 ? 177.859 154.998 124.911 1.00 15.20  ? 312 CYS A O   1 
ATOM   2424  C CB  . CYS A 1 311 ? 176.254 157.012 127.038 1.00 10.33  ? 312 CYS A CB  1 
ATOM   2425  S SG  . CYS A 1 311 ? 176.468 155.583 128.113 1.00 20.79  ? 312 CYS A SG  1 
ATOM   2426  N N   . TRP A 1 312 ? 176.040 156.028 124.080 1.00 13.43  ? 313 TRP A N   1 
ATOM   2427  C CA  . TRP A 1 312 ? 175.772 154.930 123.162 1.00 9.24   ? 313 TRP A CA  1 
ATOM   2428  C C   . TRP A 1 312 ? 176.814 154.852 122.054 1.00 10.97  ? 313 TRP A C   1 
ATOM   2429  O O   . TRP A 1 312 ? 177.172 153.749 121.627 1.00 14.03  ? 313 TRP A O   1 
ATOM   2430  C CB  . TRP A 1 312 ? 174.365 155.066 122.593 1.00 7.12   ? 313 TRP A CB  1 
ATOM   2431  C CG  . TRP A 1 312 ? 173.312 154.739 123.600 1.00 7.87   ? 313 TRP A CG  1 
ATOM   2432  C CD1 . TRP A 1 312 ? 173.504 154.196 124.836 1.00 8.73   ? 313 TRP A CD1 1 
ATOM   2433  C CD2 . TRP A 1 312 ? 171.900 154.929 123.462 1.00 8.93   ? 313 TRP A CD2 1 
ATOM   2434  N NE1 . TRP A 1 312 ? 172.302 154.037 125.476 1.00 8.93   ? 313 TRP A NE1 1 
ATOM   2435  C CE2 . TRP A 1 312 ? 171.300 154.480 124.654 1.00 10.58  ? 313 TRP A CE2 1 
ATOM   2436  C CE3 . TRP A 1 312 ? 171.084 155.437 122.447 1.00 6.43   ? 313 TRP A CE3 1 
ATOM   2437  C CZ2 . TRP A 1 312 ? 169.926 154.525 124.858 1.00 7.51   ? 313 TRP A CZ2 1 
ATOM   2438  C CZ3 . TRP A 1 312 ? 169.724 155.478 122.652 1.00 6.43   ? 313 TRP A CZ3 1 
ATOM   2439  C CH2 . TRP A 1 312 ? 169.158 155.026 123.847 1.00 7.80   ? 313 TRP A CH2 1 
ATOM   2440  N N   . THR A 1 313 ? 177.338 155.993 121.597 1.00 11.67  ? 314 THR A N   1 
ATOM   2441  C CA  . THR A 1 313 ? 178.437 155.962 120.639 1.00 12.48  ? 314 THR A CA  1 
ATOM   2442  C C   . THR A 1 313 ? 179.672 155.298 121.236 1.00 14.42  ? 314 THR A C   1 
ATOM   2443  O O   . THR A 1 313 ? 180.313 154.461 120.588 1.00 16.77  ? 314 THR A O   1 
ATOM   2444  C CB  . THR A 1 313 ? 178.765 157.380 120.174 1.00 12.14  ? 314 THR A CB  1 
ATOM   2445  O OG1 . THR A 1 313 ? 177.613 157.957 119.551 1.00 12.15  ? 314 THR A OG1 1 
ATOM   2446  C CG2 . THR A 1 313 ? 179.917 157.368 119.186 1.00 14.69  ? 314 THR A CG2 1 
ATOM   2447  N N   . TYR A 1 314 ? 180.014 155.645 122.479 1.00 14.09  ? 315 TYR A N   1 
ATOM   2448  C CA  . TYR A 1 314 ? 181.188 155.043 123.099 1.00 13.94  ? 315 TYR A CA  1 
ATOM   2449  C C   . TYR A 1 314 ? 180.985 153.554 123.350 1.00 17.15  ? 315 TYR A C   1 
ATOM   2450  O O   . TYR A 1 314 ? 181.923 152.764 123.209 1.00 19.52  ? 315 TYR A O   1 
ATOM   2451  C CB  . TYR A 1 314 ? 181.533 155.763 124.398 1.00 15.75  ? 315 TYR A CB  1 
ATOM   2452  C CG  . TYR A 1 314 ? 182.838 155.303 125.002 1.00 20.25  ? 315 TYR A CG  1 
ATOM   2453  C CD1 . TYR A 1 314 ? 184.026 155.408 124.296 1.00 19.46  ? 315 TYR A CD1 1 
ATOM   2454  C CD2 . TYR A 1 314 ? 182.880 154.754 126.273 1.00 20.89  ? 315 TYR A CD2 1 
ATOM   2455  C CE1 . TYR A 1 314 ? 185.216 154.986 124.841 1.00 20.01  ? 315 TYR A CE1 1 
ATOM   2456  C CE2 . TYR A 1 314 ? 184.067 154.329 126.825 1.00 19.36  ? 315 TYR A CE2 1 
ATOM   2457  C CZ  . TYR A 1 314 ? 185.231 154.447 126.106 1.00 21.58  ? 315 TYR A CZ  1 
ATOM   2458  O OH  . TYR A 1 314 ? 186.417 154.023 126.656 1.00 29.72  ? 315 TYR A OH  1 
ATOM   2459  N N   . GLU A 1 315 ? 179.771 153.146 123.724 1.00 18.57  ? 316 GLU A N   1 
ATOM   2460  C CA  . GLU A 1 315 ? 179.516 151.725 123.943 1.00 14.99  ? 316 GLU A CA  1 
ATOM   2461  C C   . GLU A 1 315 ? 179.561 150.942 122.637 1.00 14.68  ? 316 GLU A C   1 
ATOM   2462  O O   . GLU A 1 315 ? 180.024 149.797 122.611 1.00 17.27  ? 316 GLU A O   1 
ATOM   2463  C CB  . GLU A 1 315 ? 178.174 151.534 124.642 1.00 14.83  ? 316 GLU A CB  1 
ATOM   2464  C CG  . GLU A 1 315 ? 178.155 152.054 126.063 1.00 13.82  ? 316 GLU A CG  1 
ATOM   2465  C CD  . GLU A 1 315 ? 176.789 151.964 126.692 1.00 18.88  ? 316 GLU A CD  1 
ATOM   2466  O OE1 . GLU A 1 315 ? 175.791 151.991 125.946 1.00 19.87  ? 316 GLU A OE1 1 
ATOM   2467  O OE2 . GLU A 1 315 ? 176.708 151.872 127.933 1.00 23.61  ? 316 GLU A OE2 1 
ATOM   2468  N N   . THR A 1 316 ? 179.084 151.537 121.542 1.00 16.18  ? 317 THR A N   1 
ATOM   2469  C CA  . THR A 1 316 ? 179.198 150.877 120.246 1.00 17.51  ? 317 THR A CA  1 
ATOM   2470  C C   . THR A 1 316 ? 180.653 150.774 119.807 1.00 21.40  ? 317 THR A C   1 
ATOM   2471  O O   . THR A 1 316 ? 181.046 149.787 119.175 1.00 24.20  ? 317 THR A O   1 
ATOM   2472  C CB  . THR A 1 316 ? 178.374 151.621 119.198 1.00 15.35  ? 317 THR A CB  1 
ATOM   2473  O OG1 . THR A 1 316 ? 177.103 151.977 119.754 1.00 15.22  ? 317 THR A OG1 1 
ATOM   2474  C CG2 . THR A 1 316 ? 178.156 150.746 117.981 1.00 13.06  ? 317 THR A CG2 1 
ATOM   2475  N N   . ALA A 1 317 ? 181.464 151.787 120.119 1.00 20.56  ? 318 ALA A N   1 
ATOM   2476  C CA  . ALA A 1 317 ? 182.896 151.692 119.849 1.00 19.34  ? 318 ALA A CA  1 
ATOM   2477  C C   . ALA A 1 317 ? 183.543 150.598 120.688 1.00 22.31  ? 318 ALA A C   1 
ATOM   2478  O O   . ALA A 1 317 ? 184.427 149.878 120.210 1.00 25.74  ? 318 ALA A O   1 
ATOM   2479  C CB  . ALA A 1 317 ? 183.571 153.036 120.110 1.00 18.58  ? 318 ALA A CB  1 
ATOM   2480  N N   . VAL A 1 318 ? 183.120 150.468 121.947 1.00 21.98  ? 319 VAL A N   1 
ATOM   2481  C CA  . VAL A 1 318 ? 183.647 149.426 122.824 1.00 22.20  ? 319 VAL A CA  1 
ATOM   2482  C C   . VAL A 1 318 ? 183.299 148.044 122.285 1.00 24.88  ? 319 VAL A C   1 
ATOM   2483  O O   . VAL A 1 318 ? 184.128 147.127 122.303 1.00 26.57  ? 319 VAL A O   1 
ATOM   2484  C CB  . VAL A 1 318 ? 183.121 149.628 124.258 1.00 21.84  ? 319 VAL A CB  1 
ATOM   2485  C CG1 . VAL A 1 318 ? 183.177 148.329 125.041 1.00 20.63  ? 319 VAL A CG1 1 
ATOM   2486  C CG2 . VAL A 1 318 ? 183.910 150.712 124.961 1.00 19.63  ? 319 VAL A CG2 1 
ATOM   2487  N N   . ALA A 1 319 ? 182.066 147.872 121.800 1.00 26.34  ? 320 ALA A N   1 
ATOM   2488  C CA  . ALA A 1 319 ? 181.667 146.588 121.231 1.00 23.42  ? 320 ALA A CA  1 
ATOM   2489  C C   . ALA A 1 319 ? 182.527 146.225 120.027 1.00 23.41  ? 320 ALA A C   1 
ATOM   2490  O O   . ALA A 1 319 ? 182.938 145.070 119.875 1.00 28.16  ? 320 ALA A O   1 
ATOM   2491  C CB  . ALA A 1 319 ? 180.190 146.623 120.844 1.00 21.83  ? 320 ALA A CB  1 
ATOM   2492  N N   . LEU A 1 320 ? 182.814 147.198 119.165 1.00 23.67  ? 321 LEU A N   1 
ATOM   2493  C CA  . LEU A 1 320 ? 183.653 146.975 117.995 1.00 23.84  ? 321 LEU A CA  1 
ATOM   2494  C C   . LEU A 1 320 ? 185.130 146.846 118.334 1.00 27.77  ? 321 LEU A C   1 
ATOM   2495  O O   . LEU A 1 320 ? 185.923 146.537 117.438 1.00 28.22  ? 321 LEU A O   1 
ATOM   2496  C CB  . LEU A 1 320 ? 183.471 148.113 116.989 1.00 22.99  ? 321 LEU A CB  1 
ATOM   2497  C CG  . LEU A 1 320 ? 182.189 148.142 116.161 1.00 21.09  ? 321 LEU A CG  1 
ATOM   2498  C CD1 . LEU A 1 320 ? 181.940 149.541 115.646 1.00 21.57  ? 321 LEU A CD1 1 
ATOM   2499  C CD2 . LEU A 1 320 ? 182.280 147.159 115.013 1.00 19.86  ? 321 LEU A CD2 1 
ATOM   2500  N N   . ASP A 1 321 ? 185.515 147.077 119.592 1.00 32.95  ? 322 ASP A N   1 
ATOM   2501  C CA  . ASP A 1 321 ? 186.918 147.086 120.009 1.00 32.16  ? 322 ASP A CA  1 
ATOM   2502  C C   . ASP A 1 321 ? 187.716 148.124 119.225 1.00 36.03  ? 322 ASP A C   1 
ATOM   2503  O O   . ASP A 1 321 ? 188.841 147.874 118.789 1.00 39.03  ? 322 ASP A O   1 
ATOM   2504  C CB  . ASP A 1 321 ? 187.551 145.700 119.878 1.00 35.72  ? 322 ASP A CB  1 
ATOM   2505  C CG  . ASP A 1 321 ? 187.800 145.048 121.219 1.00 45.83  ? 322 ASP A CG  1 
ATOM   2506  O OD1 . ASP A 1 321 ? 187.460 145.663 122.250 1.00 42.74  ? 322 ASP A OD1 1 
ATOM   2507  O OD2 . ASP A 1 321 ? 188.337 143.921 121.242 1.00 52.32  ? 322 ASP A OD2 1 
ATOM   2508  N N   . CYS A 1 322 ? 187.125 149.302 119.048 1.00 34.62  ? 323 CYS A N   1 
ATOM   2509  C CA  . CYS A 1 322 ? 187.726 150.390 118.292 1.00 34.14  ? 323 CYS A CA  1 
ATOM   2510  C C   . CYS A 1 322 ? 187.862 151.607 119.193 1.00 37.45  ? 323 CYS A C   1 
ATOM   2511  O O   . CYS A 1 322 ? 186.966 151.895 119.992 1.00 42.30  ? 323 CYS A O   1 
ATOM   2512  C CB  . CYS A 1 322 ? 186.884 150.731 117.060 1.00 34.82  ? 323 CYS A CB  1 
ATOM   2513  S SG  . CYS A 1 322 ? 187.719 151.772 115.846 1.00 73.05  ? 323 CYS A SG  1 
ATOM   2514  N N   . GLU A 1 323 ? 188.980 152.313 119.069 1.00 42.84  ? 324 GLU A N   1 
ATOM   2515  C CA  . GLU A 1 323 ? 189.215 153.520 119.846 1.00 45.94  ? 324 GLU A CA  1 
ATOM   2516  C C   . GLU A 1 323 ? 188.831 154.749 119.035 1.00 40.21  ? 324 GLU A C   1 
ATOM   2517  O O   . GLU A 1 323 ? 189.141 154.845 117.845 1.00 41.04  ? 324 GLU A O   1 
ATOM   2518  C CB  . GLU A 1 323 ? 190.680 153.610 120.276 1.00 50.44  ? 324 GLU A CB  1 
ATOM   2519  C CG  . GLU A 1 323 ? 191.161 152.411 121.070 1.00 55.16  ? 324 GLU A CG  1 
ATOM   2520  C CD  . GLU A 1 323 ? 191.576 152.779 122.479 1.00 72.54  ? 324 GLU A CD  1 
ATOM   2521  O OE1 . GLU A 1 323 ? 191.218 152.040 123.420 1.00 76.28  ? 324 GLU A OE1 1 
ATOM   2522  O OE2 . GLU A 1 323 ? 192.260 153.810 122.646 1.00 77.01  ? 324 GLU A OE2 1 
ATOM   2523  N N   . ILE A 1 324 ? 188.149 155.685 119.687 1.00 34.22  ? 325 ILE A N   1 
ATOM   2524  C CA  . ILE A 1 324 ? 187.715 156.914 119.030 1.00 32.32  ? 325 ILE A CA  1 
ATOM   2525  C C   . ILE A 1 324 ? 188.247 158.106 119.817 1.00 34.92  ? 325 ILE A C   1 
ATOM   2526  O O   . ILE A 1 324 ? 188.325 158.049 121.053 1.00 32.68  ? 325 ILE A O   1 
ATOM   2527  C CB  . ILE A 1 324 ? 186.185 156.965 118.889 1.00 30.15  ? 325 ILE A CB  1 
ATOM   2528  C CG1 . ILE A 1 324 ? 185.501 156.791 120.245 1.00 27.61  ? 325 ILE A CG1 1 
ATOM   2529  C CG2 . ILE A 1 324 ? 185.706 155.900 117.919 1.00 29.73  ? 325 ILE A CG2 1 
ATOM   2530  C CD1 . ILE A 1 324 ? 183.994 156.813 120.170 1.00 18.54  ? 325 ILE A CD1 1 
ATOM   2531  N N   . PRO A 1 325 ? 188.636 159.190 119.150 1.00 36.57  ? 326 PRO A N   1 
ATOM   2532  C CA  . PRO A 1 325 ? 189.190 160.343 119.866 1.00 36.58  ? 326 PRO A CA  1 
ATOM   2533  C C   . PRO A 1 325 ? 188.143 161.054 120.709 1.00 37.04  ? 326 PRO A C   1 
ATOM   2534  O O   . PRO A 1 325 ? 186.940 160.996 120.449 1.00 36.86  ? 326 PRO A O   1 
ATOM   2535  C CB  . PRO A 1 325 ? 189.698 161.249 118.740 1.00 37.98  ? 326 PRO A CB  1 
ATOM   2536  C CG  . PRO A 1 325 ? 188.919 160.840 117.547 1.00 33.34  ? 326 PRO A CG  1 
ATOM   2537  C CD  . PRO A 1 325 ? 188.697 159.370 117.691 1.00 33.17  ? 326 PRO A CD  1 
ATOM   2538  N N   . ASN A 1 326 ? 188.634 161.741 121.743 1.00 37.23  ? 327 ASN A N   1 
ATOM   2539  C CA  . ASN A 1 326 ? 187.764 162.510 122.624 1.00 37.46  ? 327 ASN A CA  1 
ATOM   2540  C C   . ASN A 1 326 ? 187.152 163.719 121.928 1.00 37.93  ? 327 ASN A C   1 
ATOM   2541  O O   . ASN A 1 326 ? 186.171 164.275 122.431 1.00 39.34  ? 327 ASN A O   1 
ATOM   2542  C CB  . ASN A 1 326 ? 188.544 162.960 123.860 1.00 37.47  ? 327 ASN A CB  1 
ATOM   2543  C CG  . ASN A 1 326 ? 187.641 163.404 124.990 1.00 38.15  ? 327 ASN A CG  1 
ATOM   2544  O OD1 . ASN A 1 326 ? 186.515 162.934 125.121 1.00 36.93  ? 327 ASN A OD1 1 
ATOM   2545  N ND2 . ASN A 1 326 ? 188.136 164.313 125.819 1.00 39.25  ? 327 ASN A ND2 1 
ATOM   2546  N N   . GLU A 1 327 ? 187.698 164.133 120.790 1.00 36.52  ? 328 GLU A N   1 
ATOM   2547  C CA  . GLU A 1 327 ? 187.195 165.288 120.059 1.00 36.82  ? 328 GLU A CA  1 
ATOM   2548  C C   . GLU A 1 327 ? 186.100 164.838 119.100 1.00 36.04  ? 328 GLU A C   1 
ATOM   2549  O O   . GLU A 1 327 ? 186.365 164.082 118.160 1.00 38.47  ? 328 GLU A O   1 
ATOM   2550  C CB  . GLU A 1 327 ? 188.326 165.977 119.299 1.00 38.14  ? 328 GLU A CB  1 
ATOM   2551  C CG  . GLU A 1 327 ? 189.573 166.215 120.129 1.00 43.47  ? 328 GLU A CG  1 
ATOM   2552  C CD  . GLU A 1 327 ? 190.622 165.141 119.922 1.00 51.08  ? 328 GLU A CD  1 
ATOM   2553  O OE1 . GLU A 1 327 ? 190.745 164.640 118.786 1.00 49.60  ? 328 GLU A OE1 1 
ATOM   2554  O OE2 . GLU A 1 327 ? 191.323 164.796 120.896 1.00 53.78  ? 328 GLU A OE2 1 
ATOM   2555  N N   . LEU A 1 328 ? 184.881 165.307 119.334 1.00 34.76  ? 329 LEU A N   1 
ATOM   2556  C CA  . LEU A 1 328 ? 183.762 164.912 118.495 1.00 32.28  ? 329 LEU A CA  1 
ATOM   2557  C C   . LEU A 1 328 ? 183.979 165.405 117.067 1.00 35.11  ? 329 LEU A C   1 
ATOM   2558  O O   . LEU A 1 328 ? 184.464 166.524 116.863 1.00 37.48  ? 329 LEU A O   1 
ATOM   2559  C CB  . LEU A 1 328 ? 182.451 165.475 119.045 1.00 31.82  ? 329 LEU A CB  1 
ATOM   2560  C CG  . LEU A 1 328 ? 181.904 164.836 120.319 1.00 30.38  ? 329 LEU A CG  1 
ATOM   2561  C CD1 . LEU A 1 328 ? 180.632 165.529 120.739 1.00 29.90  ? 329 LEU A CD1 1 
ATOM   2562  C CD2 . LEU A 1 328 ? 181.660 163.357 120.119 1.00 30.72  ? 329 LEU A CD2 1 
ATOM   2563  N N   . PRO A 1 329 ? 183.637 164.609 116.063 1.00 36.88  ? 330 PRO A N   1 
ATOM   2564  C CA  . PRO A 1 329 ? 183.771 165.044 114.672 1.00 38.82  ? 330 PRO A CA  1 
ATOM   2565  C C   . PRO A 1 329 ? 182.656 166.018 114.308 1.00 40.32  ? 330 PRO A C   1 
ATOM   2566  O O   . PRO A 1 329 ? 181.847 166.417 115.141 1.00 44.49  ? 330 PRO A O   1 
ATOM   2567  C CB  . PRO A 1 329 ? 183.656 163.734 113.894 1.00 34.61  ? 330 PRO A CB  1 
ATOM   2568  C CG  . PRO A 1 329 ? 182.766 162.901 114.734 1.00 31.04  ? 330 PRO A CG  1 
ATOM   2569  C CD  . PRO A 1 329 ? 183.092 163.244 116.159 1.00 33.14  ? 330 PRO A CD  1 
ATOM   2570  N N   . TYR A 1 330 ? 182.626 166.399 113.037 1.00 38.58  ? 331 TYR A N   1 
ATOM   2571  C CA  . TYR A 1 330 ? 181.586 167.277 112.520 1.00 43.62  ? 331 TYR A CA  1 
ATOM   2572  C C   . TYR A 1 330 ? 180.398 166.432 112.081 1.00 45.01  ? 331 TYR A C   1 
ATOM   2573  O O   . TYR A 1 330 ? 180.544 165.538 111.241 1.00 46.14  ? 331 TYR A O   1 
ATOM   2574  C CB  . TYR A 1 330 ? 182.110 168.117 111.356 1.00 47.66  ? 331 TYR A CB  1 
ATOM   2575  C CG  . TYR A 1 330 ? 181.043 168.945 110.677 1.00 53.10  ? 331 TYR A CG  1 
ATOM   2576  C CD1 . TYR A 1 330 ? 180.620 170.150 111.221 1.00 53.71  ? 331 TYR A CD1 1 
ATOM   2577  C CD2 . TYR A 1 330 ? 180.454 168.518 109.494 1.00 55.72  ? 331 TYR A CD2 1 
ATOM   2578  C CE1 . TYR A 1 330 ? 179.643 170.908 110.606 1.00 56.56  ? 331 TYR A CE1 1 
ATOM   2579  C CE2 . TYR A 1 330 ? 179.476 169.269 108.871 1.00 59.75  ? 331 TYR A CE2 1 
ATOM   2580  C CZ  . TYR A 1 330 ? 179.074 170.462 109.432 1.00 62.78  ? 331 TYR A CZ  1 
ATOM   2581  O OH  . TYR A 1 330 ? 178.101 171.212 108.813 1.00 71.56  ? 331 TYR A OH  1 
ATOM   2582  N N   . ASN A 1 331 ? 179.226 166.713 112.647 1.00 44.74  ? 332 ASN A N   1 
ATOM   2583  C CA  . ASN A 1 331 ? 178.004 166.003 112.300 1.00 42.23  ? 332 ASN A CA  1 
ATOM   2584  C C   . ASN A 1 331 ? 176.885 167.017 112.109 1.00 44.21  ? 332 ASN A C   1 
ATOM   2585  O O   . ASN A 1 331 ? 177.075 168.225 112.278 1.00 46.51  ? 332 ASN A O   1 
ATOM   2586  C CB  . ASN A 1 331 ? 177.640 164.961 113.364 1.00 37.12  ? 332 ASN A CB  1 
ATOM   2587  C CG  . ASN A 1 331 ? 177.935 165.431 114.771 1.00 37.81  ? 332 ASN A CG  1 
ATOM   2588  O OD1 . ASN A 1 331 ? 179.075 165.742 115.109 1.00 38.55  ? 332 ASN A OD1 1 
ATOM   2589  N ND2 . ASN A 1 331 ? 176.907 165.475 115.606 1.00 41.30  ? 332 ASN A ND2 1 
ATOM   2590  N N   . ASP A 1 332 ? 175.702 166.514 111.747 1.00 42.72  ? 333 ASP A N   1 
ATOM   2591  C CA  . ASP A 1 332 ? 174.553 167.382 111.523 1.00 41.25  ? 333 ASP A CA  1 
ATOM   2592  C C   . ASP A 1 332 ? 174.058 168.038 112.803 1.00 42.95  ? 333 ASP A C   1 
ATOM   2593  O O   . ASP A 1 332 ? 173.306 169.015 112.733 1.00 46.88  ? 333 ASP A O   1 
ATOM   2594  C CB  . ASP A 1 332 ? 173.413 166.593 110.880 1.00 38.99  ? 333 ASP A CB  1 
ATOM   2595  C CG  . ASP A 1 332 ? 173.868 165.783 109.685 1.00 48.05  ? 333 ASP A CG  1 
ATOM   2596  O OD1 . ASP A 1 332 ? 175.086 165.761 109.410 1.00 49.55  ? 333 ASP A OD1 1 
ATOM   2597  O OD2 . ASP A 1 332 ? 173.007 165.170 109.021 1.00 51.47  ? 333 ASP A OD2 1 
ATOM   2598  N N   . TYR A 1 333 ? 174.457 167.527 113.963 1.00 40.31  ? 334 TYR A N   1 
ATOM   2599  C CA  . TYR A 1 333 ? 174.004 168.018 115.256 1.00 39.92  ? 334 TYR A CA  1 
ATOM   2600  C C   . TYR A 1 333 ? 175.182 168.479 116.102 1.00 40.19  ? 334 TYR A C   1 
ATOM   2601  O O   . TYR A 1 333 ? 175.246 168.227 117.305 1.00 40.68  ? 334 TYR A O   1 
ATOM   2602  C CB  . TYR A 1 333 ? 173.191 166.949 115.981 1.00 36.88  ? 334 TYR A CB  1 
ATOM   2603  C CG  . TYR A 1 333 ? 172.112 166.348 115.113 1.00 34.26  ? 334 TYR A CG  1 
ATOM   2604  C CD1 . TYR A 1 333 ? 170.877 166.963 114.988 1.00 36.40  ? 334 TYR A CD1 1 
ATOM   2605  C CD2 . TYR A 1 333 ? 172.334 165.177 114.405 1.00 32.71  ? 334 TYR A CD2 1 
ATOM   2606  C CE1 . TYR A 1 333 ? 169.892 166.426 114.190 1.00 32.35  ? 334 TYR A CE1 1 
ATOM   2607  C CE2 . TYR A 1 333 ? 171.354 164.634 113.604 1.00 30.75  ? 334 TYR A CE2 1 
ATOM   2608  C CZ  . TYR A 1 333 ? 170.136 165.263 113.500 1.00 29.49  ? 334 TYR A CZ  1 
ATOM   2609  O OH  . TYR A 1 333 ? 169.155 164.728 112.704 1.00 28.95  ? 334 TYR A OH  1 
ATOM   2610  N N   . PHE A 1 334 ? 176.135 169.167 115.469 1.00 41.93  ? 335 PHE A N   1 
ATOM   2611  C CA  . PHE A 1 334 ? 177.315 169.639 116.183 1.00 44.68  ? 335 PHE A CA  1 
ATOM   2612  C C   . PHE A 1 334 ? 176.964 170.704 117.214 1.00 46.19  ? 335 PHE A C   1 
ATOM   2613  O O   . PHE A 1 334 ? 177.696 170.879 118.194 1.00 42.54  ? 335 PHE A O   1 
ATOM   2614  C CB  . PHE A 1 334 ? 178.343 170.178 115.188 1.00 43.82  ? 335 PHE A CB  1 
ATOM   2615  C CG  . PHE A 1 334 ? 179.751 170.172 115.705 1.00 43.52  ? 335 PHE A CG  1 
ATOM   2616  C CD1 . PHE A 1 334 ? 180.274 169.050 116.320 1.00 43.26  ? 335 PHE A CD1 1 
ATOM   2617  C CD2 . PHE A 1 334 ? 180.555 171.290 115.572 1.00 46.57  ? 335 PHE A CD2 1 
ATOM   2618  C CE1 . PHE A 1 334 ? 181.569 169.045 116.795 1.00 45.20  ? 335 PHE A CE1 1 
ATOM   2619  C CE2 . PHE A 1 334 ? 181.851 171.290 116.044 1.00 45.91  ? 335 PHE A CE2 1 
ATOM   2620  C CZ  . PHE A 1 334 ? 182.358 170.166 116.657 1.00 46.20  ? 335 PHE A CZ  1 
ATOM   2621  N N   . GLU A 1 335 ? 175.855 171.419 117.016 1.00 48.79  ? 336 GLU A N   1 
ATOM   2622  C CA  . GLU A 1 335 ? 175.459 172.463 117.952 1.00 47.16  ? 336 GLU A CA  1 
ATOM   2623  C C   . GLU A 1 335 ? 174.884 171.901 119.245 1.00 46.72  ? 336 GLU A C   1 
ATOM   2624  O O   . GLU A 1 335 ? 174.798 172.631 120.238 1.00 48.82  ? 336 GLU A O   1 
ATOM   2625  C CB  . GLU A 1 335 ? 174.442 173.396 117.293 1.00 50.18  ? 336 GLU A CB  1 
ATOM   2626  C CG  . GLU A 1 335 ? 173.224 172.687 116.720 1.00 58.01  ? 336 GLU A CG  1 
ATOM   2627  C CD  . GLU A 1 335 ? 173.382 172.343 115.251 1.00 64.76  ? 336 GLU A CD  1 
ATOM   2628  O OE1 . GLU A 1 335 ? 174.378 172.781 114.639 1.00 63.65  ? 336 GLU A OE1 1 
ATOM   2629  O OE2 . GLU A 1 335 ? 172.509 171.633 114.709 1.00 64.51  ? 336 GLU A OE2 1 
ATOM   2630  N N   . TYR A 1 336 ? 174.486 170.627 119.258 1.00 45.34  ? 337 TYR A N   1 
ATOM   2631  C CA  . TYR A 1 336 ? 173.930 170.027 120.464 1.00 39.83  ? 337 TYR A CA  1 
ATOM   2632  C C   . TYR A 1 336 ? 174.993 169.728 121.511 1.00 38.47  ? 337 TYR A C   1 
ATOM   2633  O O   . TYR A 1 336 ? 174.664 169.627 122.697 1.00 38.31  ? 337 TYR A O   1 
ATOM   2634  C CB  . TYR A 1 336 ? 173.188 168.736 120.121 1.00 36.07  ? 337 TYR A CB  1 
ATOM   2635  C CG  . TYR A 1 336 ? 171.835 168.931 119.480 1.00 37.97  ? 337 TYR A CG  1 
ATOM   2636  C CD1 . TYR A 1 336 ? 171.724 169.313 118.152 1.00 40.57  ? 337 TYR A CD1 1 
ATOM   2637  C CD2 . TYR A 1 336 ? 170.668 168.723 120.201 1.00 34.60  ? 337 TYR A CD2 1 
ATOM   2638  C CE1 . TYR A 1 336 ? 170.491 169.487 117.561 1.00 38.84  ? 337 TYR A CE1 1 
ATOM   2639  C CE2 . TYR A 1 336 ? 169.430 168.895 119.619 1.00 34.29  ? 337 TYR A CE2 1 
ATOM   2640  C CZ  . TYR A 1 336 ? 169.348 169.276 118.299 1.00 37.88  ? 337 TYR A CZ  1 
ATOM   2641  O OH  . TYR A 1 336 ? 168.118 169.450 117.711 1.00 38.96  ? 337 TYR A OH  1 
ATOM   2642  N N   . PHE A 1 337 ? 176.253 169.586 121.105 1.00 40.49  ? 338 PHE A N   1 
ATOM   2643  C CA  . PHE A 1 337 ? 177.318 169.124 121.985 1.00 42.33  ? 338 PHE A CA  1 
ATOM   2644  C C   . PHE A 1 337 ? 178.224 170.247 122.472 1.00 46.77  ? 338 PHE A C   1 
ATOM   2645  O O   . PHE A 1 337 ? 179.298 169.969 123.013 1.00 46.56  ? 338 PHE A O   1 
ATOM   2646  C CB  . PHE A 1 337 ? 178.150 168.054 121.278 1.00 36.22  ? 338 PHE A CB  1 
ATOM   2647  C CG  . PHE A 1 337 ? 177.358 166.847 120.866 1.00 32.51  ? 338 PHE A CG  1 
ATOM   2648  C CD1 . PHE A 1 337 ? 177.131 165.815 121.757 1.00 27.71  ? 338 PHE A CD1 1 
ATOM   2649  C CD2 . PHE A 1 337 ? 176.835 166.748 119.590 1.00 33.45  ? 338 PHE A CD2 1 
ATOM   2650  C CE1 . PHE A 1 337 ? 176.400 164.709 121.382 1.00 27.01  ? 338 PHE A CE1 1 
ATOM   2651  C CE2 . PHE A 1 337 ? 176.103 165.645 119.211 1.00 30.84  ? 338 PHE A CE2 1 
ATOM   2652  C CZ  . PHE A 1 337 ? 175.885 164.624 120.108 1.00 28.89  ? 338 PHE A CZ  1 
ATOM   2653  N N   . GLY A 1 338 ? 177.826 171.499 122.292 1.00 48.07  ? 339 GLY A N   1 
ATOM   2654  C CA  . GLY A 1 338 ? 178.631 172.615 122.732 1.00 51.70  ? 339 GLY A CA  1 
ATOM   2655  C C   . GLY A 1 338 ? 178.553 172.818 124.227 1.00 61.03  ? 339 GLY A C   1 
ATOM   2656  O O   . GLY A 1 338 ? 177.701 172.254 124.931 1.00 64.56  ? 339 GLY A O   1 
ATOM   2657  N N   . PRO A 1 339 ? 179.463 173.652 124.747 1.00 62.98  ? 340 PRO A N   1 
ATOM   2658  C CA  . PRO A 1 339 ? 180.547 174.349 124.047 1.00 61.71  ? 340 PRO A CA  1 
ATOM   2659  C C   . PRO A 1 339 ? 181.873 173.596 124.104 1.00 60.30  ? 340 PRO A C   1 
ATOM   2660  O O   . PRO A 1 339 ? 182.852 174.010 123.489 1.00 58.41  ? 340 PRO A O   1 
ATOM   2661  C CB  . PRO A 1 339 ? 180.616 175.677 124.803 1.00 60.73  ? 340 PRO A CB  1 
ATOM   2662  C CG  . PRO A 1 339 ? 180.319 175.277 126.229 1.00 61.65  ? 340 PRO A CG  1 
ATOM   2663  C CD  . PRO A 1 339 ? 179.357 174.101 126.147 1.00 60.54  ? 340 PRO A CD  1 
ATOM   2664  N N   . ASP A 1 340 ? 181.938 172.487 124.843 1.00 58.33  ? 341 ASP A N   1 
ATOM   2665  C CA  . ASP A 1 340 ? 183.188 171.745 124.958 1.00 57.88  ? 341 ASP A CA  1 
ATOM   2666  C C   . ASP A 1 340 ? 183.489 170.944 123.697 1.00 52.41  ? 341 ASP A C   1 
ATOM   2667  O O   . ASP A 1 340 ? 184.649 170.852 123.283 1.00 50.73  ? 341 ASP A O   1 
ATOM   2668  C CB  . ASP A 1 340 ? 183.140 170.821 126.177 1.00 60.96  ? 341 ASP A CB  1 
ATOM   2669  C CG  . ASP A 1 340 ? 181.881 169.977 126.220 1.00 63.58  ? 341 ASP A CG  1 
ATOM   2670  O OD1 . ASP A 1 340 ? 180.803 170.496 125.862 1.00 62.24  ? 341 ASP A OD1 1 
ATOM   2671  O OD2 . ASP A 1 340 ? 181.969 168.794 126.612 1.00 60.44  ? 341 ASP A OD2 1 
ATOM   2672  N N   . PHE A 1 341 ? 182.457 170.365 123.077 1.00 51.57  ? 342 PHE A N   1 
ATOM   2673  C CA  . PHE A 1 341 ? 182.607 169.507 121.900 1.00 48.47  ? 342 PHE A CA  1 
ATOM   2674  C C   . PHE A 1 341 ? 183.543 168.335 122.190 1.00 45.57  ? 342 PHE A C   1 
ATOM   2675  O O   . PHE A 1 341 ? 184.449 168.022 121.416 1.00 42.60  ? 342 PHE A O   1 
ATOM   2676  C CB  . PHE A 1 341 ? 183.083 170.309 120.687 1.00 50.08  ? 342 PHE A CB  1 
ATOM   2677  C CG  . PHE A 1 341 ? 182.210 171.484 120.359 1.00 49.36  ? 342 PHE A CG  1 
ATOM   2678  C CD1 . PHE A 1 341 ? 180.946 171.298 119.833 1.00 47.42  ? 342 PHE A CD1 1 
ATOM   2679  C CD2 . PHE A 1 341 ? 182.653 172.775 120.581 1.00 52.65  ? 342 PHE A CD2 1 
ATOM   2680  C CE1 . PHE A 1 341 ? 180.141 172.376 119.533 1.00 48.25  ? 342 PHE A CE1 1 
ATOM   2681  C CE2 . PHE A 1 341 ? 181.851 173.857 120.283 1.00 53.37  ? 342 PHE A CE2 1 
ATOM   2682  C CZ  . PHE A 1 341 ? 180.594 173.657 119.759 1.00 49.68  ? 342 PHE A CZ  1 
ATOM   2683  N N   . LYS A 1 342 ? 183.314 167.684 123.327 1.00 44.00  ? 343 LYS A N   1 
ATOM   2684  C CA  . LYS A 1 342 ? 184.068 166.512 123.740 1.00 41.31  ? 343 LYS A CA  1 
ATOM   2685  C C   . LYS A 1 342 ? 183.119 165.336 123.922 1.00 38.51  ? 343 LYS A C   1 
ATOM   2686  O O   . LYS A 1 342 ? 181.934 165.513 124.220 1.00 37.56  ? 343 LYS A O   1 
ATOM   2687  C CB  . LYS A 1 342 ? 184.831 166.764 125.046 1.00 42.94  ? 343 LYS A CB  1 
ATOM   2688  C CG  . LYS A 1 342 ? 185.900 167.838 124.959 1.00 47.98  ? 343 LYS A CG  1 
ATOM   2689  C CD  . LYS A 1 342 ? 186.956 167.488 123.929 1.00 46.64  ? 343 LYS A CD  1 
ATOM   2690  C CE  . LYS A 1 342 ? 188.118 168.463 123.983 1.00 44.59  ? 343 LYS A CE  1 
ATOM   2691  N NZ  . LYS A 1 342 ? 188.784 168.604 122.661 1.00 48.86  ? 343 LYS A NZ  1 
ATOM   2692  N N   . LEU A 1 343 ? 183.651 164.128 123.737 1.00 32.52  ? 344 LEU A N   1 
ATOM   2693  C CA  . LEU A 1 343 ? 182.834 162.928 123.870 1.00 28.79  ? 344 LEU A CA  1 
ATOM   2694  C C   . LEU A 1 343 ? 182.566 162.581 125.329 1.00 28.15  ? 344 LEU A C   1 
ATOM   2695  O O   . LEU A 1 343 ? 181.476 162.107 125.665 1.00 26.66  ? 344 LEU A O   1 
ATOM   2696  C CB  . LEU A 1 343 ? 183.512 161.756 123.160 1.00 31.50  ? 344 LEU A CB  1 
ATOM   2697  C CG  . LEU A 1 343 ? 182.911 160.360 123.340 1.00 27.22  ? 344 LEU A CG  1 
ATOM   2698  C CD1 . LEU A 1 343 ? 181.601 160.223 122.588 1.00 22.28  ? 344 LEU A CD1 1 
ATOM   2699  C CD2 . LEU A 1 343 ? 183.897 159.306 122.886 1.00 25.48  ? 344 LEU A CD2 1 
ATOM   2700  N N   . HIS A 1 344 ? 183.531 162.821 126.208 1.00 28.74  ? 345 HIS A N   1 
ATOM   2701  C CA  . HIS A 1 344 ? 183.469 162.346 127.582 1.00 27.77  ? 345 HIS A CA  1 
ATOM   2702  C C   . HIS A 1 344 ? 183.019 163.457 128.521 1.00 33.65  ? 345 HIS A C   1 
ATOM   2703  O O   . HIS A 1 344 ? 183.410 164.617 128.364 1.00 38.55  ? 345 HIS A O   1 
ATOM   2704  C CB  . HIS A 1 344 ? 184.827 161.801 128.019 1.00 27.91  ? 345 HIS A CB  1 
ATOM   2705  C CG  . HIS A 1 344 ? 185.184 160.499 127.374 1.00 29.51  ? 345 HIS A CG  1 
ATOM   2706  N ND1 . HIS A 1 344 ? 184.535 159.320 127.669 1.00 27.31  ? 345 HIS A ND1 1 
ATOM   2707  C CD2 . HIS A 1 344 ? 186.114 160.192 126.440 1.00 30.53  ? 345 HIS A CD2 1 
ATOM   2708  C CE1 . HIS A 1 344 ? 185.053 158.343 126.949 1.00 26.26  ? 345 HIS A CE1 1 
ATOM   2709  N NE2 . HIS A 1 344 ? 186.012 158.845 126.194 1.00 30.68  ? 345 HIS A NE2 1 
ATOM   2710  N N   . ILE A 1 345 ? 182.201 163.090 129.499 1.00 34.25  ? 346 ILE A N   1 
ATOM   2711  C CA  . ILE A 1 345 ? 181.615 164.040 130.421 1.00 33.52  ? 346 ILE A CA  1 
ATOM   2712  C C   . ILE A 1 345 ? 182.336 163.958 131.761 1.00 37.58  ? 346 ILE A C   1 
ATOM   2713  O O   . ILE A 1 345 ? 183.100 163.035 132.028 1.00 38.84  ? 346 ILE A O   1 
ATOM   2714  C CB  . ILE A 1 345 ? 180.095 163.807 130.591 1.00 30.57  ? 346 ILE A CB  1 
ATOM   2715  C CG1 . ILE A 1 345 ? 179.838 162.496 131.339 1.00 29.21  ? 346 ILE A CG1 1 
ATOM   2716  C CG2 . ILE A 1 345 ? 179.405 163.800 129.240 1.00 28.10  ? 346 ILE A CG2 1 
ATOM   2717  C CD1 . ILE A 1 345 ? 178.380 162.230 131.632 1.00 24.80  ? 346 ILE A CD1 1 
ATOM   2718  N N   . SER A 1 346 ? 182.088 164.947 132.624 1.00 39.54  ? 347 SER A N   1 
ATOM   2719  C CA  . SER A 1 346 ? 182.662 165.012 133.957 1.00 41.32  ? 347 SER A CA  1 
ATOM   2720  C C   . SER A 1 346 ? 181.578 164.855 135.016 1.00 40.46  ? 347 SER A C   1 
ATOM   2721  O O   . SER A 1 346 ? 180.462 165.354 134.837 1.00 40.68  ? 347 SER A O   1 
ATOM   2722  C CB  . SER A 1 346 ? 183.393 166.342 134.178 1.00 44.18  ? 347 SER A CB  1 
ATOM   2723  O OG  . SER A 1 346 ? 184.682 166.320 133.593 1.00 49.74  ? 347 SER A OG  1 
ATOM   2724  N N   . PRO A 1 347 ? 181.870 164.173 136.120 1.00 40.70  ? 348 PRO A N   1 
ATOM   2725  C CA  . PRO A 1 347 ? 180.850 163.970 137.152 1.00 36.61  ? 348 PRO A CA  1 
ATOM   2726  C C   . PRO A 1 347 ? 180.600 165.235 137.959 1.00 38.34  ? 348 PRO A C   1 
ATOM   2727  O O   . PRO A 1 347 ? 181.402 166.170 137.979 1.00 38.98  ? 348 PRO A O   1 
ATOM   2728  C CB  . PRO A 1 347 ? 181.448 162.865 138.026 1.00 32.77  ? 348 PRO A CB  1 
ATOM   2729  C CG  . PRO A 1 347 ? 182.913 163.026 137.867 1.00 36.05  ? 348 PRO A CG  1 
ATOM   2730  C CD  . PRO A 1 347 ? 183.146 163.524 136.467 1.00 39.76  ? 348 PRO A CD  1 
ATOM   2731  N N   . SER A 1 348 ? 179.455 165.249 138.633 1.00 36.50  ? 349 SER A N   1 
ATOM   2732  C CA  . SER A 1 348 ? 179.078 166.365 139.488 1.00 35.10  ? 349 SER A CA  1 
ATOM   2733  C C   . SER A 1 348 ? 179.697 166.174 140.872 1.00 34.84  ? 349 SER A C   1 
ATOM   2734  O O   . SER A 1 348 ? 180.549 165.308 141.088 1.00 33.26  ? 349 SER A O   1 
ATOM   2735  C CB  . SER A 1 348 ? 177.560 166.498 139.547 1.00 37.68  ? 349 SER A CB  1 
ATOM   2736  O OG  . SER A 1 348 ? 176.987 165.480 140.345 1.00 30.88  ? 349 SER A OG  1 
ATOM   2737  N N   . ASN A 1 349 ? 179.271 166.990 141.834 1.00 37.66  ? 350 ASN A N   1 
ATOM   2738  C CA  . ASN A 1 349 ? 179.835 166.986 143.177 1.00 37.64  ? 350 ASN A CA  1 
ATOM   2739  C C   . ASN A 1 349 ? 178.866 166.415 144.207 1.00 39.35  ? 350 ASN A C   1 
ATOM   2740  O O   . ASN A 1 349 ? 178.945 166.751 145.391 1.00 42.81  ? 350 ASN A O   1 
ATOM   2741  C CB  . ASN A 1 349 ? 180.263 168.397 143.575 1.00 38.25  ? 350 ASN A CB  1 
ATOM   2742  C CG  . ASN A 1 349 ? 181.517 168.851 142.856 1.00 47.96  ? 350 ASN A CG  1 
ATOM   2743  O OD1 . ASN A 1 349 ? 181.460 169.673 141.942 1.00 47.00  ? 350 ASN A OD1 1 
ATOM   2744  N ND2 . ASN A 1 349 ? 182.661 168.317 143.268 1.00 49.47  ? 350 ASN A ND2 1 
ATOM   2745  N N   . MET A 1 350 ? 177.947 165.556 143.776 1.00 30.66  ? 351 MET A N   1 
ATOM   2746  C CA  . MET A 1 350 ? 176.980 164.990 144.702 1.00 30.16  ? 351 MET A CA  1 
ATOM   2747  C C   . MET A 1 350 ? 177.628 163.931 145.586 1.00 33.67  ? 351 MET A C   1 
ATOM   2748  O O   . MET A 1 350 ? 178.605 163.281 145.207 1.00 33.84  ? 351 MET A O   1 
ATOM   2749  C CB  . MET A 1 350 ? 175.794 164.391 143.947 1.00 32.13  ? 351 MET A CB  1 
ATOM   2750  C CG  . MET A 1 350 ? 176.165 163.482 142.798 1.00 32.03  ? 351 MET A CG  1 
ATOM   2751  S SD  . MET A 1 350 ? 174.723 162.948 141.860 1.00 34.51  ? 351 MET A SD  1 
ATOM   2752  C CE  . MET A 1 350 ? 173.472 162.917 143.137 1.00 18.68  ? 351 MET A CE  1 
ATOM   2753  N N   . THR A 1 351 ? 177.068 163.768 146.781 1.00 36.16  ? 352 THR A N   1 
ATOM   2754  C CA  . THR A 1 351 ? 177.590 162.820 147.754 1.00 33.80  ? 352 THR A CA  1 
ATOM   2755  C C   . THR A 1 351 ? 177.101 161.411 147.442 1.00 32.34  ? 352 THR A C   1 
ATOM   2756  O O   . THR A 1 351 ? 175.953 161.212 147.035 1.00 31.47  ? 352 THR A O   1 
ATOM   2757  C CB  . THR A 1 351 ? 177.164 163.226 149.167 1.00 33.51  ? 352 THR A CB  1 
ATOM   2758  O OG1 . THR A 1 351 ? 177.570 164.577 149.418 1.00 39.81  ? 352 THR A OG1 1 
ATOM   2759  C CG2 . THR A 1 351 ? 177.797 162.321 150.209 1.00 33.64  ? 352 THR A CG2 1 
ATOM   2760  N N   . ASN A 1 352 ? 177.984 160.434 147.631 1.00 29.43  ? 353 ASN A N   1 
ATOM   2761  C CA  . ASN A 1 352 ? 177.654 159.027 147.433 1.00 25.96  ? 353 ASN A CA  1 
ATOM   2762  C C   . ASN A 1 352 ? 177.101 158.472 148.740 1.00 27.74  ? 353 ASN A C   1 
ATOM   2763  O O   . ASN A 1 352 ? 177.818 158.393 149.742 1.00 29.79  ? 353 ASN A O   1 
ATOM   2764  C CB  . ASN A 1 352 ? 178.886 158.249 146.977 1.00 23.31  ? 353 ASN A CB  1 
ATOM   2765  C CG  . ASN A 1 352 ? 178.545 156.876 146.440 1.00 24.74  ? 353 ASN A CG  1 
ATOM   2766  O OD1 . ASN A 1 352 ? 177.390 156.457 146.458 1.00 27.24  ? 353 ASN A OD1 1 
ATOM   2767  N ND2 . ASN A 1 352 ? 179.554 156.165 145.958 1.00 26.42  ? 353 ASN A ND2 1 
ATOM   2768  N N   . GLN A 1 353 ? 175.826 158.088 148.732 1.00 27.90  ? 354 GLN A N   1 
ATOM   2769  C CA  . GLN A 1 353 ? 175.182 157.535 149.916 1.00 29.51  ? 354 GLN A CA  1 
ATOM   2770  C C   . GLN A 1 353 ? 175.411 156.039 150.073 1.00 30.48  ? 354 GLN A C   1 
ATOM   2771  O O   . GLN A 1 353 ? 174.968 155.462 151.071 1.00 29.19  ? 354 GLN A O   1 
ATOM   2772  C CB  . GLN A 1 353 ? 173.678 157.821 149.882 1.00 28.41  ? 354 GLN A CB  1 
ATOM   2773  C CG  . GLN A 1 353 ? 173.314 159.215 149.406 1.00 34.17  ? 354 GLN A CG  1 
ATOM   2774  C CD  . GLN A 1 353 ? 173.404 160.255 150.504 1.00 40.41  ? 354 GLN A CD  1 
ATOM   2775  O OE1 . GLN A 1 353 ? 173.797 159.955 151.631 1.00 39.64  ? 354 GLN A OE1 1 
ATOM   2776  N NE2 . GLN A 1 353 ? 173.040 161.490 150.179 1.00 38.07  ? 354 GLN A NE2 1 
ATOM   2777  N N   . ASN A 1 354 ? 176.082 155.400 149.118 1.00 31.52  ? 355 ASN A N   1 
ATOM   2778  C CA  . ASN A 1 354 ? 176.363 153.967 149.178 1.00 28.18  ? 355 ASN A CA  1 
ATOM   2779  C C   . ASN A 1 354 ? 177.678 153.778 149.920 1.00 31.72  ? 355 ASN A C   1 
ATOM   2780  O O   . ASN A 1 354 ? 178.753 153.720 149.324 1.00 33.44  ? 355 ASN A O   1 
ATOM   2781  C CB  . ASN A 1 354 ? 176.411 153.368 147.779 1.00 24.96  ? 355 ASN A CB  1 
ATOM   2782  C CG  . ASN A 1 354 ? 175.193 153.720 146.953 1.00 25.05  ? 355 ASN A CG  1 
ATOM   2783  O OD1 . ASN A 1 354 ? 174.196 153.005 146.966 1.00 25.22  ? 355 ASN A OD1 1 
ATOM   2784  N ND2 . ASN A 1 354 ? 175.269 154.827 146.227 1.00 23.88  ? 355 ASN A ND2 1 
ATOM   2785  N N   . THR A 1 355 ? 177.588 153.694 151.243 1.00 35.28  ? 356 THR A N   1 
ATOM   2786  C CA  . THR A 1 355 ? 178.768 153.479 152.059 1.00 36.02  ? 356 THR A CA  1 
ATOM   2787  C C   . THR A 1 355 ? 179.306 152.065 151.842 1.00 38.31  ? 356 THR A C   1 
ATOM   2788  O O   . THR A 1 355 ? 178.555 151.158 151.474 1.00 37.03  ? 356 THR A O   1 
ATOM   2789  C CB  . THR A 1 355 ? 178.444 153.701 153.534 1.00 35.58  ? 356 THR A CB  1 
ATOM   2790  O OG1 . THR A 1 355 ? 177.351 152.860 153.919 1.00 36.41  ? 356 THR A OG1 1 
ATOM   2791  C CG2 . THR A 1 355 ? 178.067 155.152 153.777 1.00 36.44  ? 356 THR A CG2 1 
ATOM   2792  N N   . PRO A 1 356 ? 180.610 151.855 152.045 1.00 40.83  ? 357 PRO A N   1 
ATOM   2793  C CA  . PRO A 1 356 ? 181.177 150.517 151.813 1.00 39.24  ? 357 PRO A CA  1 
ATOM   2794  C C   . PRO A 1 356 ? 180.537 149.423 152.649 1.00 37.52  ? 357 PRO A C   1 
ATOM   2795  O O   . PRO A 1 356 ? 180.458 148.278 152.189 1.00 39.57  ? 357 PRO A O   1 
ATOM   2796  C CB  . PRO A 1 356 ? 182.659 150.703 152.166 1.00 42.61  ? 357 PRO A CB  1 
ATOM   2797  C CG  . PRO A 1 356 ? 182.916 152.151 151.948 1.00 42.54  ? 357 PRO A CG  1 
ATOM   2798  C CD  . PRO A 1 356 ? 181.653 152.852 152.344 1.00 39.16  ? 357 PRO A CD  1 
ATOM   2799  N N   . GLU A 1 357 ? 180.076 149.734 153.862 1.00 36.07  ? 358 GLU A N   1 
ATOM   2800  C CA  . GLU A 1 357 ? 179.424 148.723 154.690 1.00 35.86  ? 358 GLU A CA  1 
ATOM   2801  C C   . GLU A 1 357 ? 178.099 148.281 154.081 1.00 37.45  ? 358 GLU A C   1 
ATOM   2802  O O   . GLU A 1 357 ? 177.804 147.082 154.013 1.00 37.85  ? 358 GLU A O   1 
ATOM   2803  C CB  . GLU A 1 357 ? 179.215 149.262 156.105 1.00 36.63  ? 358 GLU A CB  1 
ATOM   2804  C CG  . GLU A 1 357 ? 180.414 150.007 156.676 1.00 43.60  ? 358 GLU A CG  1 
ATOM   2805  C CD  . GLU A 1 357 ? 180.364 151.498 156.403 1.00 49.01  ? 358 GLU A CD  1 
ATOM   2806  O OE1 . GLU A 1 357 ? 181.440 152.124 156.307 1.00 47.61  ? 358 GLU A OE1 1 
ATOM   2807  O OE2 . GLU A 1 357 ? 179.247 152.043 156.287 1.00 48.76  ? 358 GLU A OE2 1 
ATOM   2808  N N   . TYR A 1 358 ? 177.287 149.241 153.633 1.00 37.65  ? 359 TYR A N   1 
ATOM   2809  C CA  . TYR A 1 358 ? 176.016 148.922 152.989 1.00 32.24  ? 359 TYR A CA  1 
ATOM   2810  C C   . TYR A 1 358 ? 176.236 148.101 151.724 1.00 33.46  ? 359 TYR A C   1 
ATOM   2811  O O   . TYR A 1 358 ? 175.566 147.084 151.498 1.00 33.36  ? 359 TYR A O   1 
ATOM   2812  C CB  . TYR A 1 358 ? 175.272 150.225 152.684 1.00 30.33  ? 359 TYR A CB  1 
ATOM   2813  C CG  . TYR A 1 358 ? 174.089 150.112 151.750 1.00 31.17  ? 359 TYR A CG  1 
ATOM   2814  C CD1 . TYR A 1 358 ? 172.833 149.764 152.226 1.00 31.33  ? 359 TYR A CD1 1 
ATOM   2815  C CD2 . TYR A 1 358 ? 174.222 150.387 150.395 1.00 32.23  ? 359 TYR A CD2 1 
ATOM   2816  C CE1 . TYR A 1 358 ? 171.750 149.672 151.377 1.00 30.05  ? 359 TYR A CE1 1 
ATOM   2817  C CE2 . TYR A 1 358 ? 173.145 150.297 149.539 1.00 27.80  ? 359 TYR A CE2 1 
ATOM   2818  C CZ  . TYR A 1 358 ? 171.912 149.940 150.034 1.00 30.73  ? 359 TYR A CZ  1 
ATOM   2819  O OH  . TYR A 1 358 ? 170.834 149.850 149.184 1.00 27.79  ? 359 TYR A OH  1 
ATOM   2820  N N   . MET A 1 359 ? 177.194 148.525 150.897 1.00 35.33  ? 360 MET A N   1 
ATOM   2821  C CA  . MET A 1 359 ? 177.493 147.814 149.660 1.00 32.57  ? 360 MET A CA  1 
ATOM   2822  C C   . MET A 1 359 ? 177.969 146.395 149.940 1.00 33.42  ? 360 MET A C   1 
ATOM   2823  O O   . MET A 1 359 ? 177.547 145.447 149.268 1.00 34.85  ? 360 MET A O   1 
ATOM   2824  C CB  . MET A 1 359 ? 178.543 148.591 148.869 1.00 31.77  ? 360 MET A CB  1 
ATOM   2825  C CG  . MET A 1 359 ? 177.966 149.563 147.855 1.00 34.53  ? 360 MET A CG  1 
ATOM   2826  S SD  . MET A 1 359 ? 179.208 150.672 147.160 1.00 56.91  ? 360 MET A SD  1 
ATOM   2827  C CE  . MET A 1 359 ? 180.640 149.600 147.086 1.00 35.88  ? 360 MET A CE  1 
ATOM   2828  N N   . GLU A 1 360 ? 178.838 146.227 150.940 1.00 37.00  ? 361 GLU A N   1 
ATOM   2829  C CA  . GLU A 1 360 ? 179.341 144.899 151.273 1.00 37.73  ? 361 GLU A CA  1 
ATOM   2830  C C   . GLU A 1 360 ? 178.237 144.004 151.818 1.00 34.93  ? 361 GLU A C   1 
ATOM   2831  O O   . GLU A 1 360 ? 178.198 142.808 151.513 1.00 35.73  ? 361 GLU A O   1 
ATOM   2832  C CB  . GLU A 1 360 ? 180.487 145.009 152.277 1.00 39.36  ? 361 GLU A CB  1 
ATOM   2833  C CG  . GLU A 1 360 ? 181.281 143.726 152.448 1.00 44.65  ? 361 GLU A CG  1 
ATOM   2834  C CD  . GLU A 1 360 ? 181.785 143.174 151.130 1.00 47.54  ? 361 GLU A CD  1 
ATOM   2835  O OE1 . GLU A 1 360 ? 182.381 143.945 150.350 1.00 44.47  ? 361 GLU A OE1 1 
ATOM   2836  O OE2 . GLU A 1 360 ? 181.587 141.968 150.872 1.00 50.57  ? 361 GLU A OE2 1 
ATOM   2837  N N   . LYS A 1 361 ? 177.335 144.556 152.631 1.00 33.56  ? 362 LYS A N   1 
ATOM   2838  C CA  . LYS A 1 361 ? 176.223 143.762 153.146 1.00 32.98  ? 362 LYS A CA  1 
ATOM   2839  C C   . LYS A 1 361 ? 175.312 143.292 152.017 1.00 33.59  ? 362 LYS A C   1 
ATOM   2840  O O   . LYS A 1 361 ? 174.909 142.121 151.972 1.00 34.84  ? 362 LYS A O   1 
ATOM   2841  C CB  . LYS A 1 361 ? 175.436 144.574 154.173 1.00 38.18  ? 362 LYS A CB  1 
ATOM   2842  C CG  . LYS A 1 361 ? 175.984 144.496 155.585 1.00 39.16  ? 362 LYS A CG  1 
ATOM   2843  C CD  . LYS A 1 361 ? 174.868 144.280 156.589 1.00 41.38  ? 362 LYS A CD  1 
ATOM   2844  C CE  . LYS A 1 361 ? 175.373 144.399 158.015 1.00 44.28  ? 362 LYS A CE  1 
ATOM   2845  N NZ  . LYS A 1 361 ? 174.575 143.563 158.952 1.00 43.34  ? 362 LYS A NZ  1 
ATOM   2846  N N   . ILE A 1 362 ? 174.981 144.194 151.086 1.00 35.13  ? 363 ILE A N   1 
ATOM   2847  C CA  . ILE A 1 362 ? 174.141 143.810 149.952 1.00 31.42  ? 363 ILE A CA  1 
ATOM   2848  C C   . ILE A 1 362 ? 174.841 142.755 149.105 1.00 28.38  ? 363 ILE A C   1 
ATOM   2849  O O   . ILE A 1 362 ? 174.223 141.774 148.670 1.00 29.22  ? 363 ILE A O   1 
ATOM   2850  C CB  . ILE A 1 362 ? 173.762 145.046 149.113 1.00 31.16  ? 363 ILE A CB  1 
ATOM   2851  C CG1 . ILE A 1 362 ? 173.090 146.114 149.980 1.00 28.47  ? 363 ILE A CG1 1 
ATOM   2852  C CG2 . ILE A 1 362 ? 172.859 144.645 147.954 1.00 29.40  ? 363 ILE A CG2 1 
ATOM   2853  C CD1 . ILE A 1 362 ? 171.596 145.957 150.122 1.00 30.78  ? 363 ILE A CD1 1 
ATOM   2854  N N   . LYS A 1 363 ? 176.141 142.937 148.859 1.00 30.27  ? 364 LYS A N   1 
ATOM   2855  C CA  . LYS A 1 363 ? 176.893 141.982 148.053 1.00 29.69  ? 364 LYS A CA  1 
ATOM   2856  C C   . LYS A 1 363 ? 176.937 140.610 148.712 1.00 30.96  ? 364 LYS A C   1 
ATOM   2857  O O   . LYS A 1 363 ? 176.776 139.587 148.038 1.00 31.93  ? 364 LYS A O   1 
ATOM   2858  C CB  . LYS A 1 363 ? 178.307 142.509 147.818 1.00 31.36  ? 364 LYS A CB  1 
ATOM   2859  C CG  . LYS A 1 363 ? 179.131 141.690 146.847 1.00 33.55  ? 364 LYS A CG  1 
ATOM   2860  C CD  . LYS A 1 363 ? 180.064 142.577 146.041 1.00 31.78  ? 364 LYS A CD  1 
ATOM   2861  C CE  . LYS A 1 363 ? 180.902 143.461 146.948 1.00 40.27  ? 364 LYS A CE  1 
ATOM   2862  N NZ  . LYS A 1 363 ? 181.585 144.552 146.199 1.00 31.11  ? 364 LYS A NZ  1 
ATOM   2863  N N   . GLN A 1 364 ? 177.157 140.566 150.027 1.00 33.84  ? 365 GLN A N   1 
ATOM   2864  C CA  . GLN A 1 364 ? 177.195 139.291 150.735 1.00 31.90  ? 365 GLN A CA  1 
ATOM   2865  C C   . GLN A 1 364 ? 175.837 138.603 150.717 1.00 30.96  ? 365 GLN A C   1 
ATOM   2866  O O   . GLN A 1 364 ? 175.757 137.380 150.545 1.00 33.19  ? 365 GLN A O   1 
ATOM   2867  C CB  . GLN A 1 364 ? 177.673 139.503 152.170 1.00 34.16  ? 365 GLN A CB  1 
ATOM   2868  C CG  . GLN A 1 364 ? 179.185 139.478 152.340 1.00 36.78  ? 365 GLN A CG  1 
ATOM   2869  C CD  . GLN A 1 364 ? 179.876 138.564 151.344 1.00 41.33  ? 365 GLN A CD  1 
ATOM   2870  O OE1 . GLN A 1 364 ? 179.712 137.344 151.384 1.00 42.14  ? 365 GLN A OE1 1 
ATOM   2871  N NE2 . GLN A 1 364 ? 180.662 139.151 150.449 1.00 40.34  ? 365 GLN A NE2 1 
ATOM   2872  N N   . ARG A 1 365 ? 174.755 139.366 150.898 1.00 31.86  ? 366 ARG A N   1 
ATOM   2873  C CA  . ARG A 1 365 ? 173.424 138.771 150.817 1.00 31.05  ? 366 ARG A CA  1 
ATOM   2874  C C   . ARG A 1 365 ? 173.161 138.195 149.431 1.00 32.00  ? 366 ARG A C   1 
ATOM   2875  O O   . ARG A 1 365 ? 172.619 137.090 149.300 1.00 33.81  ? 366 ARG A O   1 
ATOM   2876  C CB  . ARG A 1 365 ? 172.361 139.807 151.178 1.00 31.91  ? 366 ARG A CB  1 
ATOM   2877  C CG  . ARG A 1 365 ? 171.023 139.584 150.499 1.00 34.40  ? 366 ARG A CG  1 
ATOM   2878  C CD  . ARG A 1 365 ? 170.184 138.574 151.259 1.00 35.83  ? 366 ARG A CD  1 
ATOM   2879  N NE  . ARG A 1 365 ? 170.288 138.763 152.700 1.00 40.02  ? 366 ARG A NE  1 
ATOM   2880  C CZ  . ARG A 1 365 ? 169.343 139.308 153.454 1.00 44.92  ? 366 ARG A CZ  1 
ATOM   2881  N NH1 . ARG A 1 365 ? 168.197 139.717 152.936 1.00 45.27  ? 366 ARG A NH1 1 
ATOM   2882  N NH2 . ARG A 1 365 ? 169.555 139.446 154.759 1.00 46.14  ? 366 ARG A NH2 1 
ATOM   2883  N N   . LEU A 1 366 ? 173.546 138.928 148.383 1.00 29.88  ? 367 LEU A N   1 
ATOM   2884  C CA  . LEU A 1 366 ? 173.354 138.431 147.024 1.00 28.02  ? 367 LEU A CA  1 
ATOM   2885  C C   . LEU A 1 366 ? 174.185 137.180 146.769 1.00 29.89  ? 367 LEU A C   1 
ATOM   2886  O O   . LEU A 1 366 ? 173.724 136.246 146.104 1.00 30.22  ? 367 LEU A O   1 
ATOM   2887  C CB  . LEU A 1 366 ? 173.701 139.520 146.012 1.00 31.10  ? 367 LEU A CB  1 
ATOM   2888  C CG  . LEU A 1 366 ? 172.713 140.679 145.873 1.00 31.24  ? 367 LEU A CG  1 
ATOM   2889  C CD1 . LEU A 1 366 ? 172.919 141.370 144.547 1.00 25.01  ? 367 LEU A CD1 1 
ATOM   2890  C CD2 . LEU A 1 366 ? 171.279 140.200 146.008 1.00 29.85  ? 367 LEU A CD2 1 
ATOM   2891  N N   . PHE A 1 367 ? 175.417 137.148 147.282 1.00 31.38  ? 368 PHE A N   1 
ATOM   2892  C CA  . PHE A 1 367 ? 176.256 135.963 147.131 1.00 28.62  ? 368 PHE A CA  1 
ATOM   2893  C C   . PHE A 1 367 ? 175.640 134.761 147.832 1.00 32.31  ? 368 PHE A C   1 
ATOM   2894  O O   . PHE A 1 367 ? 175.678 133.642 147.310 1.00 36.08  ? 368 PHE A O   1 
ATOM   2895  C CB  . PHE A 1 367 ? 177.657 136.235 147.677 1.00 28.54  ? 368 PHE A CB  1 
ATOM   2896  C CG  . PHE A 1 367 ? 178.539 137.004 146.737 1.00 32.86  ? 368 PHE A CG  1 
ATOM   2897  C CD1 . PHE A 1 367 ? 178.033 137.538 145.565 1.00 34.15  ? 368 PHE A CD1 1 
ATOM   2898  C CD2 . PHE A 1 367 ? 179.877 137.193 147.027 1.00 33.80  ? 368 PHE A CD2 1 
ATOM   2899  C CE1 . PHE A 1 367 ? 178.845 138.245 144.703 1.00 28.35  ? 368 PHE A CE1 1 
ATOM   2900  C CE2 . PHE A 1 367 ? 180.692 137.899 146.168 1.00 32.97  ? 368 PHE A CE2 1 
ATOM   2901  C CZ  . PHE A 1 367 ? 180.175 138.426 145.006 1.00 28.83  ? 368 PHE A CZ  1 
ATOM   2902  N N   . GLU A 1 368 ? 175.078 134.971 149.024 1.00 34.28  ? 369 GLU A N   1 
ATOM   2903  C CA  . GLU A 1 368 ? 174.390 133.885 149.716 1.00 34.37  ? 369 GLU A CA  1 
ATOM   2904  C C   . GLU A 1 368 ? 173.184 133.403 148.922 1.00 36.35  ? 369 GLU A C   1 
ATOM   2905  O O   . GLU A 1 368 ? 172.914 132.199 148.858 1.00 40.64  ? 369 GLU A O   1 
ATOM   2906  C CB  . GLU A 1 368 ? 173.964 134.335 151.113 1.00 37.31  ? 369 GLU A CB  1 
ATOM   2907  C CG  . GLU A 1 368 ? 175.115 134.538 152.080 1.00 43.16  ? 369 GLU A CG  1 
ATOM   2908  C CD  . GLU A 1 368 ? 174.687 135.241 153.352 1.00 48.91  ? 369 GLU A CD  1 
ATOM   2909  O OE1 . GLU A 1 368 ? 173.467 135.414 153.555 1.00 48.86  ? 369 GLU A OE1 1 
ATOM   2910  O OE2 . GLU A 1 368 ? 175.571 135.618 154.149 1.00 48.39  ? 369 GLU A OE2 1 
ATOM   2911  N N   . ASN A 1 369 ? 172.440 134.331 148.316 1.00 34.84  ? 370 ASN A N   1 
ATOM   2912  C CA  . ASN A 1 369 ? 171.278 133.944 147.521 1.00 32.26  ? 370 ASN A CA  1 
ATOM   2913  C C   . ASN A 1 369 ? 171.686 133.169 146.273 1.00 33.57  ? 370 ASN A C   1 
ATOM   2914  O O   . ASN A 1 369 ? 170.978 132.250 145.848 1.00 37.79  ? 370 ASN A O   1 
ATOM   2915  C CB  . ASN A 1 369 ? 170.469 135.182 147.140 1.00 32.21  ? 370 ASN A CB  1 
ATOM   2916  C CG  . ASN A 1 369 ? 169.372 135.490 148.135 1.00 35.12  ? 370 ASN A CG  1 
ATOM   2917  O OD1 . ASN A 1 369 ? 168.914 134.612 148.863 1.00 44.49  ? 370 ASN A OD1 1 
ATOM   2918  N ND2 . ASN A 1 369 ? 168.942 136.744 148.170 1.00 36.33  ? 370 ASN A ND2 1 
ATOM   2919  N N   . LEU A 1 370 ? 172.819 133.530 145.666 1.00 33.78  ? 371 LEU A N   1 
ATOM   2920  C CA  . LEU A 1 370 ? 173.249 132.883 144.431 1.00 31.92  ? 371 LEU A CA  1 
ATOM   2921  C C   . LEU A 1 370 ? 173.773 131.473 144.659 1.00 35.98  ? 371 LEU A C   1 
ATOM   2922  O O   . LEU A 1 370 ? 173.789 130.674 143.718 1.00 39.69  ? 371 LEU A O   1 
ATOM   2923  C CB  . LEU A 1 370 ? 174.325 133.724 143.743 1.00 29.68  ? 371 LEU A CB  1 
ATOM   2924  C CG  . LEU A 1 370 ? 173.842 134.910 142.908 1.00 27.77  ? 371 LEU A CG  1 
ATOM   2925  C CD1 . LEU A 1 370 ? 174.983 135.876 142.640 1.00 22.38  ? 371 LEU A CD1 1 
ATOM   2926  C CD2 . LEU A 1 370 ? 173.221 134.428 141.608 1.00 22.84  ? 371 LEU A CD2 1 
ATOM   2927  N N   . ARG A 1 371 ? 174.202 131.150 145.878 1.00 39.42  ? 372 ARG A N   1 
ATOM   2928  C CA  . ARG A 1 371 ? 174.754 129.835 146.171 1.00 37.59  ? 372 ARG A CA  1 
ATOM   2929  C C   . ARG A 1 371 ? 173.684 128.771 146.373 1.00 40.96  ? 372 ARG A C   1 
ATOM   2930  O O   . ARG A 1 371 ? 174.027 127.597 146.538 1.00 49.28  ? 372 ARG A O   1 
ATOM   2931  C CB  . ARG A 1 371 ? 175.647 129.908 147.410 1.00 36.56  ? 372 ARG A CB  1 
ATOM   2932  C CG  . ARG A 1 371 ? 177.104 130.201 147.102 1.00 40.09  ? 372 ARG A CG  1 
ATOM   2933  C CD  . ARG A 1 371 ? 177.851 130.646 148.345 1.00 43.91  ? 372 ARG A CD  1 
ATOM   2934  N NE  . ARG A 1 371 ? 178.947 131.554 148.030 1.00 42.79  ? 372 ARG A NE  1 
ATOM   2935  C CZ  . ARG A 1 371 ? 179.423 132.471 148.861 1.00 42.83  ? 372 ARG A CZ  1 
ATOM   2936  N NH1 . ARG A 1 371 ? 178.920 132.633 150.074 1.00 37.95  ? 372 ARG A NH1 1 
ATOM   2937  N NH2 . ARG A 1 371 ? 180.430 133.245 148.466 1.00 43.98  ? 372 ARG A NH2 1 
ATOM   2938  N N   . MET A 1 372 ? 172.406 129.149 146.363 1.00 39.97  ? 373 MET A N   1 
ATOM   2939  C CA  . MET A 1 372 ? 171.303 128.216 146.537 1.00 42.52  ? 373 MET A CA  1 
ATOM   2940  C C   . MET A 1 372 ? 170.725 127.743 145.208 1.00 45.42  ? 373 MET A C   1 
ATOM   2941  O O   . MET A 1 372 ? 169.651 127.133 145.188 1.00 48.24  ? 373 MET A O   1 
ATOM   2942  C CB  . MET A 1 372 ? 170.208 128.852 147.393 1.00 45.81  ? 373 MET A CB  1 
ATOM   2943  C CG  . MET A 1 372 ? 170.704 129.409 148.716 1.00 49.38  ? 373 MET A CG  1 
ATOM   2944  S SD  . MET A 1 372 ? 169.622 128.997 150.096 1.00 67.49  ? 373 MET A SD  1 
ATOM   2945  C CE  . MET A 1 372 ? 169.659 127.208 150.035 1.00 52.89  ? 373 MET A CE  1 
ATOM   2946  N N   . LEU A 1 373 ? 171.412 128.014 144.101 1.00 46.33  ? 374 LEU A N   1 
ATOM   2947  C CA  . LEU A 1 373 ? 170.934 127.615 142.784 1.00 49.01  ? 374 LEU A CA  1 
ATOM   2948  C C   . LEU A 1 373 ? 171.120 126.117 142.598 1.00 53.90  ? 374 LEU A C   1 
ATOM   2949  O O   . LEU A 1 373 ? 172.239 125.618 142.779 1.00 56.34  ? 374 LEU A O   1 
ATOM   2950  C CB  . LEU A 1 373 ? 171.676 128.365 141.692 1.00 47.90  ? 374 LEU A CB  1 
ATOM   2951  C CG  . LEU A 1 373 ? 170.962 129.541 141.027 1.00 39.11  ? 374 LEU A CG  1 
ATOM   2952  C CD1 . LEU A 1 373 ? 170.325 130.442 142.061 1.00 34.56  ? 374 LEU A CD1 1 
ATOM   2953  C CD2 . LEU A 1 373 ? 171.939 130.318 140.170 1.00 33.76  ? 374 LEU A CD2 1 
ATOM   2954  N N   . PRO A 1 374 ? 170.069 125.365 142.245 1.00 58.24  ? 375 PRO A N   1 
ATOM   2955  C CA  . PRO A 1 374 ? 170.165 123.926 141.981 1.00 60.84  ? 375 PRO A CA  1 
ATOM   2956  C C   . PRO A 1 374 ? 171.072 123.610 140.797 1.00 57.53  ? 375 PRO A C   1 
ATOM   2957  O O   . PRO A 1 374 ? 170.563 123.472 139.685 1.00 59.75  ? 375 PRO A O   1 
ATOM   2958  C CB  . PRO A 1 374 ? 168.717 123.528 141.675 1.00 58.34  ? 375 PRO A CB  1 
ATOM   2959  C CG  . PRO A 1 374 ? 167.889 124.574 142.340 1.00 54.55  ? 375 PRO A CG  1 
ATOM   2960  C CD  . PRO A 1 374 ? 168.676 125.839 142.199 1.00 50.70  ? 375 PRO A CD  1 
ATOM   2961  N N   . SER B 2 10  ? 180.153 156.584 190.814 1.00 63.75  ? 26  SER B N   1 
ATOM   2962  C CA  . SER B 2 10  ? 179.129 155.855 190.075 1.00 68.65  ? 26  SER B CA  1 
ATOM   2963  C C   . SER B 2 10  ? 179.534 154.394 189.891 1.00 73.23  ? 26  SER B C   1 
ATOM   2964  O O   . SER B 2 10  ? 178.753 153.576 189.400 1.00 64.46  ? 26  SER B O   1 
ATOM   2965  C CB  . SER B 2 10  ? 178.877 156.516 188.719 1.00 63.20  ? 26  SER B CB  1 
ATOM   2966  O OG  . SER B 2 10  ? 178.372 157.830 188.880 1.00 57.46  ? 26  SER B OG  1 
ATOM   2967  N N   . MET B 2 11  ? 180.767 154.077 190.284 1.00 72.49  ? 27  MET B N   1 
ATOM   2968  C CA  . MET B 2 11  ? 181.257 152.705 190.289 1.00 71.26  ? 27  MET B CA  1 
ATOM   2969  C C   . MET B 2 11  ? 181.119 152.033 191.645 1.00 71.56  ? 27  MET B C   1 
ATOM   2970  O O   . MET B 2 11  ? 180.850 150.829 191.704 1.00 72.54  ? 27  MET B O   1 
ATOM   2971  C CB  . MET B 2 11  ? 182.726 152.662 189.855 1.00 72.97  ? 27  MET B CB  1 
ATOM   2972  C CG  . MET B 2 11  ? 182.944 152.188 188.427 1.00 76.94  ? 27  MET B CG  1 
ATOM   2973  S SD  . MET B 2 11  ? 182.310 150.523 188.141 1.00 91.98  ? 27  MET B SD  1 
ATOM   2974  C CE  . MET B 2 11  ? 181.520 150.730 186.548 1.00 68.16  ? 27  MET B CE  1 
ATOM   2975  N N   . ASP B 2 12  ? 181.300 152.780 192.731 1.00 70.49  ? 28  ASP B N   1 
ATOM   2976  C CA  . ASP B 2 12  ? 181.047 152.288 194.077 1.00 70.14  ? 28  ASP B CA  1 
ATOM   2977  C C   . ASP B 2 12  ? 179.632 152.591 194.545 1.00 66.63  ? 28  ASP B C   1 
ATOM   2978  O O   . ASP B 2 12  ? 179.291 152.285 195.693 1.00 61.76  ? 28  ASP B O   1 
ATOM   2979  C CB  . ASP B 2 12  ? 182.057 152.892 195.059 1.00 71.88  ? 28  ASP B CB  1 
ATOM   2980  C CG  . ASP B 2 12  ? 182.231 152.051 196.310 1.00 82.50  ? 28  ASP B CG  1 
ATOM   2981  O OD1 . ASP B 2 12  ? 181.777 150.887 196.314 1.00 82.85  ? 28  ASP B OD1 1 
ATOM   2982  O OD2 . ASP B 2 12  ? 182.819 152.554 197.291 1.00 89.12  ? 28  ASP B OD2 1 
ATOM   2983  N N   . GLU B 2 13  ? 178.806 153.181 193.686 1.00 61.78  ? 29  GLU B N   1 
ATOM   2984  C CA  . GLU B 2 13  ? 177.440 153.545 194.034 1.00 51.15  ? 29  GLU B CA  1 
ATOM   2985  C C   . GLU B 2 13  ? 176.517 152.370 193.742 1.00 46.91  ? 29  GLU B C   1 
ATOM   2986  O O   . GLU B 2 13  ? 176.468 151.881 192.609 1.00 51.67  ? 29  GLU B O   1 
ATOM   2987  C CB  . GLU B 2 13  ? 177.000 154.777 193.245 1.00 46.57  ? 29  GLU B CB  1 
ATOM   2988  C CG  . GLU B 2 13  ? 176.724 155.999 194.097 1.00 44.86  ? 29  GLU B CG  1 
ATOM   2989  C CD  . GLU B 2 13  ? 176.349 157.210 193.269 1.00 47.52  ? 29  GLU B CD  1 
ATOM   2990  O OE1 . GLU B 2 13  ? 175.248 157.211 192.681 1.00 45.72  ? 29  GLU B OE1 1 
ATOM   2991  O OE2 . GLU B 2 13  ? 177.154 158.162 193.208 1.00 46.55  ? 29  GLU B OE2 1 
ATOM   2992  N N   . ASN B 2 14  ? 175.794 151.913 194.761 1.00 36.66  ? 30  ASN B N   1 
ATOM   2993  C CA  . ASN B 2 14  ? 174.785 150.882 194.577 1.00 34.27  ? 30  ASN B CA  1 
ATOM   2994  C C   . ASN B 2 14  ? 173.597 151.181 195.475 1.00 28.42  ? 30  ASN B C   1 
ATOM   2995  O O   . ASN B 2 14  ? 173.762 151.623 196.614 1.00 29.55  ? 30  ASN B O   1 
ATOM   2996  C CB  . ASN B 2 14  ? 175.344 149.478 194.858 1.00 35.75  ? 30  ASN B CB  1 
ATOM   2997  C CG  . ASN B 2 14  ? 175.686 149.261 196.309 1.00 32.69  ? 30  ASN B CG  1 
ATOM   2998  O OD1 . ASN B 2 14  ? 176.170 150.164 196.985 1.00 35.89  ? 30  ASN B OD1 1 
ATOM   2999  N ND2 . ASN B 2 14  ? 175.450 148.051 196.794 1.00 30.87  ? 30  ASN B ND2 1 
ATOM   3000  N N   . TYR B 2 15  ? 172.398 150.932 194.952 1.00 27.23  ? 31  TYR B N   1 
ATOM   3001  C CA  . TYR B 2 15  ? 171.156 151.319 195.605 1.00 20.84  ? 31  TYR B CA  1 
ATOM   3002  C C   . TYR B 2 15  ? 170.859 150.525 196.868 1.00 22.01  ? 31  TYR B C   1 
ATOM   3003  O O   . TYR B 2 15  ? 169.810 150.748 197.477 1.00 25.96  ? 31  TYR B O   1 
ATOM   3004  C CB  . TYR B 2 15  ? 169.996 151.181 194.620 1.00 19.97  ? 31  TYR B CB  1 
ATOM   3005  C CG  . TYR B 2 15  ? 170.223 151.907 193.315 1.00 21.67  ? 31  TYR B CG  1 
ATOM   3006  C CD1 . TYR B 2 15  ? 170.372 153.284 193.285 1.00 22.18  ? 31  TYR B CD1 1 
ATOM   3007  C CD2 . TYR B 2 15  ? 170.294 151.214 192.115 1.00 25.56  ? 31  TYR B CD2 1 
ATOM   3008  C CE1 . TYR B 2 15  ? 170.581 153.951 192.098 1.00 24.49  ? 31  TYR B CE1 1 
ATOM   3009  C CE2 . TYR B 2 15  ? 170.503 151.875 190.921 1.00 22.73  ? 31  TYR B CE2 1 
ATOM   3010  C CZ  . TYR B 2 15  ? 170.646 153.242 190.920 1.00 24.89  ? 31  TYR B CZ  1 
ATOM   3011  O OH  . TYR B 2 15  ? 170.854 153.908 189.738 1.00 27.52  ? 31  TYR B OH  1 
ATOM   3012  N N   . PHE B 2 16  ? 171.738 149.614 197.278 1.00 23.18  ? 32  PHE B N   1 
ATOM   3013  C CA  . PHE B 2 16  ? 171.525 148.821 198.478 1.00 21.76  ? 32  PHE B CA  1 
ATOM   3014  C C   . PHE B 2 16  ? 172.437 149.212 199.630 1.00 26.72  ? 32  PHE B C   1 
ATOM   3015  O O   . PHE B 2 16  ? 172.207 148.760 200.756 1.00 26.95  ? 32  PHE B O   1 
ATOM   3016  C CB  . PHE B 2 16  ? 171.714 147.330 198.166 1.00 24.15  ? 32  PHE B CB  1 
ATOM   3017  C CG  . PHE B 2 16  ? 170.614 146.742 197.333 1.00 24.32  ? 32  PHE B CG  1 
ATOM   3018  C CD1 . PHE B 2 16  ? 170.629 146.867 195.955 1.00 24.91  ? 32  PHE B CD1 1 
ATOM   3019  C CD2 . PHE B 2 16  ? 169.566 146.065 197.927 1.00 23.81  ? 32  PHE B CD2 1 
ATOM   3020  C CE1 . PHE B 2 16  ? 169.620 146.330 195.188 1.00 23.65  ? 32  PHE B CE1 1 
ATOM   3021  C CE2 . PHE B 2 16  ? 168.554 145.526 197.165 1.00 23.87  ? 32  PHE B CE2 1 
ATOM   3022  C CZ  . PHE B 2 16  ? 168.581 145.659 195.793 1.00 27.00  ? 32  PHE B CZ  1 
ATOM   3023  N N   . VAL B 2 17  ? 173.462 150.028 199.385 1.00 29.20  ? 33  VAL B N   1 
ATOM   3024  C CA  . VAL B 2 17  ? 174.359 150.484 200.441 1.00 27.49  ? 33  VAL B CA  1 
ATOM   3025  C C   . VAL B 2 17  ? 174.409 152.005 200.465 1.00 26.61  ? 33  VAL B C   1 
ATOM   3026  O O   . VAL B 2 17  ? 174.118 152.625 201.492 1.00 33.01  ? 33  VAL B O   1 
ATOM   3027  C CB  . VAL B 2 17  ? 175.770 149.894 200.273 1.00 28.70  ? 33  VAL B CB  1 
ATOM   3028  C CG1 . VAL B 2 17  ? 176.676 150.378 201.388 1.00 32.41  ? 33  VAL B CG1 1 
ATOM   3029  C CG2 . VAL B 2 17  ? 175.708 148.387 200.272 1.00 26.34  ? 33  VAL B CG2 1 
ATOM   3030  N N   . ASN B 2 18  ? 174.780 152.620 199.344 1.00 25.57  ? 34  ASN B N   1 
ATOM   3031  C CA  . ASN B 2 18  ? 174.853 154.073 199.294 1.00 30.05  ? 34  ASN B CA  1 
ATOM   3032  C C   . ASN B 2 18  ? 174.731 154.553 197.856 1.00 32.76  ? 34  ASN B C   1 
ATOM   3033  O O   . ASN B 2 18  ? 175.259 153.926 196.937 1.00 38.86  ? 34  ASN B O   1 
ATOM   3034  C CB  . ASN B 2 18  ? 176.153 154.599 199.921 1.00 35.60  ? 34  ASN B CB  1 
ATOM   3035  C CG  . ASN B 2 18  ? 177.396 153.921 199.375 1.00 39.55  ? 34  ASN B CG  1 
ATOM   3036  O OD1 . ASN B 2 18  ? 177.336 153.135 198.432 1.00 41.41  ? 34  ASN B OD1 1 
ATOM   3037  N ND2 . ASN B 2 18  ? 178.539 154.227 199.976 1.00 39.66  ? 34  ASN B ND2 1 
ATOM   3038  N N   . TYR B 2 19  ? 174.037 155.673 197.676 1.00 29.21  ? 35  TYR B N   1 
ATOM   3039  C CA  . TYR B 2 19  ? 173.881 156.274 196.361 1.00 28.80  ? 35  TYR B CA  1 
ATOM   3040  C C   . TYR B 2 19  ? 173.491 157.733 196.535 1.00 29.13  ? 35  TYR B C   1 
ATOM   3041  O O   . TYR B 2 19  ? 173.089 158.163 197.618 1.00 29.72  ? 35  TYR B O   1 
ATOM   3042  C CB  . TYR B 2 19  ? 172.844 155.526 195.515 1.00 27.60  ? 35  TYR B CB  1 
ATOM   3043  C CG  . TYR B 2 19  ? 171.446 155.513 196.090 1.00 25.51  ? 35  TYR B CG  1 
ATOM   3044  C CD1 . TYR B 2 19  ? 171.101 154.643 197.114 1.00 22.94  ? 35  TYR B CD1 1 
ATOM   3045  C CD2 . TYR B 2 19  ? 170.468 156.364 195.599 1.00 23.70  ? 35  TYR B CD2 1 
ATOM   3046  C CE1 . TYR B 2 19  ? 169.829 154.626 197.633 1.00 19.89  ? 35  TYR B CE1 1 
ATOM   3047  C CE2 . TYR B 2 19  ? 169.194 156.353 196.114 1.00 22.51  ? 35  TYR B CE2 1 
ATOM   3048  C CZ  . TYR B 2 19  ? 168.881 155.484 197.130 1.00 24.05  ? 35  TYR B CZ  1 
ATOM   3049  O OH  . TYR B 2 19  ? 167.607 155.473 197.644 1.00 31.37  ? 35  TYR B OH  1 
ATOM   3050  N N   . THR B 2 20  ? 173.621 158.489 195.450 1.00 29.86  ? 36  THR B N   1 
ATOM   3051  C CA  . THR B 2 20  ? 173.292 159.908 195.445 1.00 28.37  ? 36  THR B CA  1 
ATOM   3052  C C   . THR B 2 20  ? 171.867 160.090 194.939 1.00 30.51  ? 36  THR B C   1 
ATOM   3053  O O   . THR B 2 20  ? 171.519 159.600 193.859 1.00 32.67  ? 36  THR B O   1 
ATOM   3054  C CB  . THR B 2 20  ? 174.280 160.688 194.577 1.00 28.35  ? 36  THR B CB  1 
ATOM   3055  O OG1 . THR B 2 20  ? 175.470 160.956 195.328 1.00 32.37  ? 36  THR B OG1 1 
ATOM   3056  C CG2 . THR B 2 20  ? 173.676 162.004 194.120 1.00 27.32  ? 36  THR B CG2 1 
ATOM   3057  N N   . PHE B 2 21  ? 171.045 160.785 195.720 1.00 29.40  ? 37  PHE B N   1 
ATOM   3058  C CA  . PHE B 2 21  ? 169.663 161.071 195.364 1.00 26.24  ? 37  PHE B CA  1 
ATOM   3059  C C   . PHE B 2 21  ? 169.552 162.543 194.995 1.00 26.81  ? 37  PHE B C   1 
ATOM   3060  O O   . PHE B 2 21  ? 169.829 163.415 195.824 1.00 27.78  ? 37  PHE B O   1 
ATOM   3061  C CB  . PHE B 2 21  ? 168.717 160.726 196.514 1.00 26.08  ? 37  PHE B CB  1 
ATOM   3062  C CG  . PHE B 2 21  ? 167.353 161.349 196.392 1.00 27.81  ? 37  PHE B CG  1 
ATOM   3063  C CD1 . PHE B 2 21  ? 166.522 161.030 195.333 1.00 25.33  ? 37  PHE B CD1 1 
ATOM   3064  C CD2 . PHE B 2 21  ? 166.897 162.244 197.345 1.00 25.46  ? 37  PHE B CD2 1 
ATOM   3065  C CE1 . PHE B 2 21  ? 165.270 161.599 195.222 1.00 23.92  ? 37  PHE B CE1 1 
ATOM   3066  C CE2 . PHE B 2 21  ? 165.645 162.814 197.237 1.00 23.36  ? 37  PHE B CE2 1 
ATOM   3067  C CZ  . PHE B 2 21  ? 164.832 162.490 196.175 1.00 22.75  ? 37  PHE B CZ  1 
ATOM   3068  N N   . LYS B 2 22  ? 169.151 162.815 193.758 1.00 27.73  ? 38  LYS B N   1 
ATOM   3069  C CA  . LYS B 2 22  ? 168.964 164.172 193.267 1.00 26.87  ? 38  LYS B CA  1 
ATOM   3070  C C   . LYS B 2 22  ? 167.483 164.392 192.998 1.00 29.86  ? 38  LYS B C   1 
ATOM   3071  O O   . LYS B 2 22  ? 166.875 163.654 192.217 1.00 35.44  ? 38  LYS B O   1 
ATOM   3072  C CB  . LYS B 2 22  ? 169.786 164.416 192.002 1.00 28.36  ? 38  LYS B CB  1 
ATOM   3073  C CG  . LYS B 2 22  ? 169.769 165.856 191.521 1.00 34.31  ? 38  LYS B CG  1 
ATOM   3074  C CD  . LYS B 2 22  ? 170.424 165.994 190.160 1.00 38.08  ? 38  LYS B CD  1 
ATOM   3075  C CE  . LYS B 2 22  ? 169.691 165.180 189.110 1.00 47.95  ? 38  LYS B CE  1 
ATOM   3076  N NZ  . LYS B 2 22  ? 168.261 165.574 189.001 1.00 48.85  ? 38  LYS B NZ  1 
ATOM   3077  N N   . ASP B 2 23  ? 166.911 165.404 193.641 1.00 28.10  ? 39  ASP B N   1 
ATOM   3078  C CA  . ASP B 2 23  ? 165.494 165.712 193.503 1.00 28.59  ? 39  ASP B CA  1 
ATOM   3079  C C   . ASP B 2 23  ? 165.292 166.615 192.292 1.00 38.15  ? 39  ASP B C   1 
ATOM   3080  O O   . ASP B 2 23  ? 165.802 167.740 192.259 1.00 41.86  ? 39  ASP B O   1 
ATOM   3081  C CB  . ASP B 2 23  ? 164.968 166.380 194.771 1.00 28.26  ? 39  ASP B CB  1 
ATOM   3082  C CG  . ASP B 2 23  ? 163.500 166.105 195.006 1.00 32.57  ? 39  ASP B CG  1 
ATOM   3083  O OD1 . ASP B 2 23  ? 162.883 165.411 194.175 1.00 35.56  ? 39  ASP B OD1 1 
ATOM   3084  O OD2 . ASP B 2 23  ? 162.962 166.582 196.026 1.00 31.25  ? 39  ASP B OD2 1 
ATOM   3085  N N   . ARG B 2 24  ? 164.551 166.121 191.301 1.00 39.78  ? 40  ARG B N   1 
ATOM   3086  C CA  . ARG B 2 24  ? 164.289 166.885 190.089 1.00 40.70  ? 40  ARG B CA  1 
ATOM   3087  C C   . ARG B 2 24  ? 163.220 167.951 190.276 1.00 40.94  ? 40  ARG B C   1 
ATOM   3088  O O   . ARG B 2 24  ? 163.100 168.840 189.426 1.00 41.64  ? 40  ARG B O   1 
ATOM   3089  C CB  . ARG B 2 24  ? 163.877 165.945 188.955 1.00 45.20  ? 40  ARG B CB  1 
ATOM   3090  C CG  . ARG B 2 24  ? 165.033 165.175 188.345 1.00 52.10  ? 40  ARG B CG  1 
ATOM   3091  C CD  . ARG B 2 24  ? 164.694 164.671 186.946 1.00 61.32  ? 40  ARG B CD  1 
ATOM   3092  N NE  . ARG B 2 24  ? 163.869 163.466 186.951 1.00 64.70  ? 40  ARG B NE  1 
ATOM   3093  C CZ  . ARG B 2 24  ? 164.206 162.307 187.504 1.00 61.38  ? 40  ARG B CZ  1 
ATOM   3094  N NH1 . ARG B 2 24  ? 165.386 162.126 188.075 1.00 62.03  ? 40  ARG B NH1 1 
ATOM   3095  N NH2 . ARG B 2 24  ? 163.340 161.298 187.470 1.00 51.79  ? 40  ARG B NH2 1 
ATOM   3096  N N   . SER B 2 25  ? 162.446 167.889 191.359 1.00 37.33  ? 41  SER B N   1 
ATOM   3097  C CA  . SER B 2 25  ? 161.401 168.862 191.638 1.00 38.95  ? 41  SER B CA  1 
ATOM   3098  C C   . SER B 2 25  ? 161.847 169.924 192.635 1.00 38.49  ? 41  SER B C   1 
ATOM   3099  O O   . SER B 2 25  ? 161.007 170.649 193.176 1.00 39.18  ? 41  SER B O   1 
ATOM   3100  C CB  . SER B 2 25  ? 160.147 168.152 192.147 1.00 38.64  ? 41  SER B CB  1 
ATOM   3101  O OG  . SER B 2 25  ? 160.438 167.367 193.288 1.00 36.19  ? 41  SER B OG  1 
ATOM   3102  N N   . HIS B 2 26  ? 163.153 170.025 192.891 1.00 34.98  ? 42  HIS B N   1 
ATOM   3103  C CA  . HIS B 2 26  ? 163.648 170.955 193.899 1.00 31.01  ? 42  HIS B CA  1 
ATOM   3104  C C   . HIS B 2 26  ? 163.461 172.404 193.464 1.00 35.34  ? 42  HIS B C   1 
ATOM   3105  O O   . HIS B 2 26  ? 162.962 173.231 194.235 1.00 35.81  ? 42  HIS B O   1 
ATOM   3106  C CB  . HIS B 2 26  ? 165.120 170.666 194.192 1.00 30.99  ? 42  HIS B CB  1 
ATOM   3107  C CG  . HIS B 2 26  ? 165.848 171.811 194.827 1.00 34.46  ? 42  HIS B CG  1 
ATOM   3108  N ND1 . HIS B 2 26  ? 165.742 172.109 196.168 1.00 36.34  ? 42  HIS B ND1 1 
ATOM   3109  C CD2 . HIS B 2 26  ? 166.695 172.728 194.304 1.00 30.11  ? 42  HIS B CD2 1 
ATOM   3110  C CE1 . HIS B 2 26  ? 166.489 173.163 196.443 1.00 32.28  ? 42  HIS B CE1 1 
ATOM   3111  N NE2 . HIS B 2 26  ? 167.078 173.558 195.330 1.00 31.63  ? 42  HIS B NE2 1 
ATOM   3112  N N   . SER B 2 27  ? 163.861 172.730 192.231 1.00 37.64  ? 43  SER B N   1 
ATOM   3113  C CA  . SER B 2 27  ? 163.837 174.120 191.782 1.00 31.56  ? 43  SER B CA  1 
ATOM   3114  C C   . SER B 2 27  ? 162.416 174.662 191.705 1.00 32.45  ? 43  SER B C   1 
ATOM   3115  O O   . SER B 2 27  ? 162.150 175.787 192.145 1.00 34.97  ? 43  SER B O   1 
ATOM   3116  C CB  . SER B 2 27  ? 164.528 174.243 190.426 1.00 32.55  ? 43  SER B CB  1 
ATOM   3117  O OG  . SER B 2 27  ? 165.869 173.794 190.493 1.00 37.70  ? 43  SER B OG  1 
ATOM   3118  N N   . GLY B 2 28  ? 161.493 173.883 191.143 1.00 32.79  ? 44  GLY B N   1 
ATOM   3119  C CA  . GLY B 2 28  ? 160.112 174.329 191.069 1.00 36.71  ? 44  GLY B CA  1 
ATOM   3120  C C   . GLY B 2 28  ? 159.486 174.505 192.437 1.00 34.76  ? 44  GLY B C   1 
ATOM   3121  O O   . GLY B 2 28  ? 158.754 175.467 192.675 1.00 37.82  ? 44  GLY B O   1 
ATOM   3122  N N   . ARG B 2 29  ? 159.765 173.577 193.354 1.00 32.52  ? 45  ARG B N   1 
ATOM   3123  C CA  . ARG B 2 29  ? 159.251 173.694 194.714 1.00 32.05  ? 45  ARG B CA  1 
ATOM   3124  C C   . ARG B 2 29  ? 159.800 174.933 195.406 1.00 32.86  ? 45  ARG B C   1 
ATOM   3125  O O   . ARG B 2 29  ? 159.061 175.650 196.088 1.00 35.52  ? 45  ARG B O   1 
ATOM   3126  C CB  . ARG B 2 29  ? 159.597 172.436 195.509 1.00 35.88  ? 45  ARG B CB  1 
ATOM   3127  C CG  . ARG B 2 29  ? 159.580 172.612 197.017 1.00 38.56  ? 45  ARG B CG  1 
ATOM   3128  C CD  . ARG B 2 29  ? 159.499 171.273 197.736 1.00 35.48  ? 45  ARG B CD  1 
ATOM   3129  N NE  . ARG B 2 29  ? 160.701 170.468 197.549 1.00 35.07  ? 45  ARG B NE  1 
ATOM   3130  C CZ  . ARG B 2 29  ? 160.826 169.503 196.650 1.00 31.83  ? 45  ARG B CZ  1 
ATOM   3131  N NH1 . ARG B 2 29  ? 159.832 169.177 195.842 1.00 31.34  ? 45  ARG B NH1 1 
ATOM   3132  N NH2 . ARG B 2 29  ? 161.978 168.845 196.560 1.00 30.74  ? 45  ARG B NH2 1 
ATOM   3133  N N   . VAL B 2 30  ? 161.095 175.206 195.232 1.00 35.87  ? 46  VAL B N   1 
ATOM   3134  C CA  . VAL B 2 30  ? 161.704 176.387 195.841 1.00 35.68  ? 46  VAL B CA  1 
ATOM   3135  C C   . VAL B 2 30  ? 161.071 177.658 195.287 1.00 34.88  ? 46  VAL B C   1 
ATOM   3136  O O   . VAL B 2 30  ? 160.713 178.573 196.038 1.00 33.75  ? 46  VAL B O   1 
ATOM   3137  C CB  . VAL B 2 30  ? 163.228 176.373 195.621 1.00 33.76  ? 46  VAL B CB  1 
ATOM   3138  C CG1 . VAL B 2 30  ? 163.801 177.775 195.719 1.00 30.69  ? 46  VAL B CG1 1 
ATOM   3139  C CG2 . VAL B 2 30  ? 163.892 175.458 196.622 1.00 35.78  ? 46  VAL B CG2 1 
ATOM   3140  N N   . ALA B 2 31  ? 160.918 177.729 193.963 1.00 35.83  ? 47  ALA B N   1 
ATOM   3141  C CA  . ALA B 2 31  ? 160.335 178.919 193.351 1.00 33.16  ? 47  ALA B CA  1 
ATOM   3142  C C   . ALA B 2 31  ? 158.896 179.124 193.807 1.00 35.07  ? 47  ALA B C   1 
ATOM   3143  O O   . ALA B 2 31  ? 158.498 180.241 194.159 1.00 38.59  ? 47  ALA B O   1 
ATOM   3144  C CB  . ALA B 2 31  ? 160.413 178.816 191.829 1.00 30.55  ? 47  ALA B CB  1 
ATOM   3145  N N   . GLN B 2 32  ? 158.100 178.051 193.815 1.00 34.72  ? 48  GLN B N   1 
ATOM   3146  C CA  . GLN B 2 32  ? 156.708 178.159 194.235 1.00 34.75  ? 48  GLN B CA  1 
ATOM   3147  C C   . GLN B 2 32  ? 156.600 178.569 195.697 1.00 37.65  ? 48  GLN B C   1 
ATOM   3148  O O   . GLN B 2 32  ? 155.740 179.380 196.057 1.00 43.12  ? 48  GLN B O   1 
ATOM   3149  C CB  . GLN B 2 32  ? 155.985 176.836 193.994 1.00 39.60  ? 48  GLN B CB  1 
ATOM   3150  C CG  . GLN B 2 32  ? 155.224 176.782 192.681 1.00 44.96  ? 48  GLN B CG  1 
ATOM   3151  C CD  . GLN B 2 32  ? 155.399 175.461 191.960 1.00 51.45  ? 48  GLN B CD  1 
ATOM   3152  O OE1 . GLN B 2 32  ? 155.371 174.395 192.577 1.00 51.98  ? 48  GLN B OE1 1 
ATOM   3153  N NE2 . GLN B 2 32  ? 155.583 175.523 190.647 1.00 47.53  ? 48  GLN B NE2 1 
ATOM   3154  N N   . GLY B 2 33  ? 157.457 178.015 196.555 1.00 37.97  ? 49  GLY B N   1 
ATOM   3155  C CA  . GLY B 2 33  ? 157.456 178.421 197.949 1.00 36.66  ? 49  GLY B CA  1 
ATOM   3156  C C   . GLY B 2 33  ? 157.825 179.878 198.128 1.00 39.39  ? 49  GLY B C   1 
ATOM   3157  O O   . GLY B 2 33  ? 157.227 180.581 198.944 1.00 43.44  ? 49  GLY B O   1 
ATOM   3158  N N   . ILE B 2 34  ? 158.810 180.355 197.364 1.00 41.05  ? 50  ILE B N   1 
ATOM   3159  C CA  . ILE B 2 34  ? 159.190 181.764 197.439 1.00 40.94  ? 50  ILE B CA  1 
ATOM   3160  C C   . ILE B 2 34  ? 158.017 182.649 197.033 1.00 42.93  ? 50  ILE B C   1 
ATOM   3161  O O   . ILE B 2 34  ? 157.697 183.631 197.712 1.00 45.74  ? 50  ILE B O   1 
ATOM   3162  C CB  . ILE B 2 34  ? 160.441 182.037 196.581 1.00 38.71  ? 50  ILE B CB  1 
ATOM   3163  C CG1 . ILE B 2 34  ? 161.704 182.028 197.446 1.00 38.79  ? 50  ILE B CG1 1 
ATOM   3164  C CG2 . ILE B 2 34  ? 160.340 183.376 195.862 1.00 36.44  ? 50  ILE B CG2 1 
ATOM   3165  C CD1 . ILE B 2 34  ? 162.054 180.687 198.032 1.00 41.13  ? 50  ILE B CD1 1 
ATOM   3166  N N   . MET B 2 35  ? 157.347 182.307 195.927 1.00 44.83  ? 51  MET B N   1 
ATOM   3167  C CA  . MET B 2 35  ? 156.214 183.117 195.482 1.00 45.83  ? 51  MET B CA  1 
ATOM   3168  C C   . MET B 2 35  ? 155.094 183.112 196.516 1.00 53.69  ? 51  MET B C   1 
ATOM   3169  O O   . MET B 2 35  ? 154.544 184.165 196.859 1.00 57.39  ? 51  MET B O   1 
ATOM   3170  C CB  . MET B 2 35  ? 155.694 182.626 194.129 1.00 41.30  ? 51  MET B CB  1 
ATOM   3171  C CG  . MET B 2 35  ? 156.763 182.427 193.071 1.00 41.35  ? 51  MET B CG  1 
ATOM   3172  S SD  . MET B 2 35  ? 156.174 181.616 191.570 1.00 49.21  ? 51  MET B SD  1 
ATOM   3173  C CE  . MET B 2 35  ? 154.404 181.637 191.834 1.00 44.30  ? 51  MET B CE  1 
ATOM   3174  N N   . LYS B 2 36  ? 154.755 181.932 197.038 1.00 55.00  ? 52  LYS B N   1 
ATOM   3175  C CA  . LYS B 2 36  ? 153.655 181.825 197.991 1.00 53.04  ? 52  LYS B CA  1 
ATOM   3176  C C   . LYS B 2 36  ? 153.966 182.564 199.287 1.00 55.80  ? 52  LYS B C   1 
ATOM   3177  O O   . LYS B 2 36  ? 153.082 183.199 199.874 1.00 64.12  ? 52  LYS B O   1 
ATOM   3178  C CB  . LYS B 2 36  ? 153.348 180.352 198.257 1.00 50.27  ? 52  LYS B CB  1 
ATOM   3179  C CG  . LYS B 2 36  ? 152.691 180.065 199.591 1.00 56.03  ? 52  LYS B CG  1 
ATOM   3180  C CD  . LYS B 2 36  ? 152.997 178.649 200.057 1.00 57.34  ? 52  LYS B CD  1 
ATOM   3181  C CE  . LYS B 2 36  ? 152.859 177.648 198.918 1.00 54.43  ? 52  LYS B CE  1 
ATOM   3182  N NZ  . LYS B 2 36  ? 153.724 176.453 199.115 1.00 50.39  ? 52  LYS B NZ  1 
ATOM   3183  N N   . LEU B 2 37  ? 155.215 182.498 199.751 1.00 53.93  ? 53  LEU B N   1 
ATOM   3184  C CA  . LEU B 2 37  ? 155.570 183.152 201.005 1.00 57.69  ? 53  LEU B CA  1 
ATOM   3185  C C   . LEU B 2 37  ? 155.664 184.664 200.843 1.00 60.28  ? 53  LEU B C   1 
ATOM   3186  O O   . LEU B 2 37  ? 155.219 185.413 201.718 1.00 65.43  ? 53  LEU B O   1 
ATOM   3187  C CB  . LEU B 2 37  ? 156.889 182.591 201.533 1.00 54.71  ? 53  LEU B CB  1 
ATOM   3188  C CG  . LEU B 2 37  ? 156.809 181.338 202.404 1.00 49.91  ? 53  LEU B CG  1 
ATOM   3189  C CD1 . LEU B 2 37  ? 158.158 180.650 202.453 1.00 47.00  ? 53  LEU B CD1 1 
ATOM   3190  C CD2 . LEU B 2 37  ? 156.332 181.683 203.801 1.00 53.71  ? 53  LEU B CD2 1 
ATOM   3191  N N   . CYS B 2 38  ? 156.243 185.135 199.739 1.00 59.11  ? 54  CYS B N   1 
ATOM   3192  C CA  . CYS B 2 38  ? 156.510 186.555 199.574 1.00 60.65  ? 54  CYS B CA  1 
ATOM   3193  C C   . CYS B 2 38  ? 155.384 187.314 198.886 1.00 69.68  ? 54  CYS B C   1 
ATOM   3194  O O   . CYS B 2 38  ? 155.470 188.541 198.777 1.00 72.30  ? 54  CYS B O   1 
ATOM   3195  C CB  . CYS B 2 38  ? 157.808 186.754 198.786 1.00 52.34  ? 54  CYS B CB  1 
ATOM   3196  S SG  . CYS B 2 38  ? 159.213 185.812 199.417 1.00 54.40  ? 54  CYS B SG  1 
ATOM   3197  N N   . LEU B 2 39  ? 154.346 186.631 198.401 1.00 69.76  ? 55  LEU B N   1 
ATOM   3198  C CA  . LEU B 2 39  ? 153.217 187.312 197.775 1.00 72.10  ? 55  LEU B CA  1 
ATOM   3199  C C   . LEU B 2 39  ? 152.007 187.396 198.700 1.00 74.90  ? 55  LEU B C   1 
ATOM   3200  O O   . LEU B 2 39  ? 151.530 188.493 199.005 1.00 77.25  ? 55  LEU B O   1 
ATOM   3201  C CB  . LEU B 2 39  ? 152.837 186.610 196.463 1.00 69.36  ? 55  LEU B CB  1 
ATOM   3202  C CG  . LEU B 2 39  ? 151.486 186.998 195.854 1.00 71.74  ? 55  LEU B CG  1 
ATOM   3203  C CD1 . LEU B 2 39  ? 151.514 188.426 195.331 1.00 69.83  ? 55  LEU B CD1 1 
ATOM   3204  C CD2 . LEU B 2 39  ? 151.095 186.030 194.747 1.00 66.14  ? 55  LEU B CD2 1 
ATOM   3205  N N   . GLU B 2 40  ? 151.498 186.250 199.155 1.00 73.63  ? 56  GLU B N   1 
ATOM   3206  C CA  . GLU B 2 40  ? 150.255 186.251 199.919 1.00 78.06  ? 56  GLU B CA  1 
ATOM   3207  C C   . GLU B 2 40  ? 150.468 186.767 201.338 1.00 80.82  ? 56  GLU B C   1 
ATOM   3208  O O   . GLU B 2 40  ? 149.681 187.580 201.836 1.00 85.14  ? 56  GLU B O   1 
ATOM   3209  C CB  . GLU B 2 40  ? 149.648 184.848 199.936 1.00 77.15  ? 56  GLU B CB  1 
ATOM   3210  C CG  . GLU B 2 40  ? 148.760 184.532 198.744 1.00 79.57  ? 56  GLU B CG  1 
ATOM   3211  C CD  . GLU B 2 40  ? 149.496 183.784 197.649 1.00 79.41  ? 56  GLU B CD  1 
ATOM   3212  O OE1 . GLU B 2 40  ? 150.634 184.176 197.320 1.00 75.46  ? 56  GLU B OE1 1 
ATOM   3213  O OE2 . GLU B 2 40  ? 148.935 182.802 197.118 1.00 78.33  ? 56  GLU B OE2 1 
ATOM   3214  N N   . GLU B 2 41  ? 151.527 186.311 202.007 1.00 74.52  ? 57  GLU B N   1 
ATOM   3215  C CA  . GLU B 2 41  ? 151.771 186.666 203.401 1.00 72.12  ? 57  GLU B CA  1 
ATOM   3216  C C   . GLU B 2 41  ? 152.905 187.658 203.606 1.00 73.66  ? 57  GLU B C   1 
ATOM   3217  O O   . GLU B 2 41  ? 152.824 188.478 204.523 1.00 74.71  ? 57  GLU B O   1 
ATOM   3218  C CB  . GLU B 2 41  ? 152.054 185.407 204.232 1.00 70.16  ? 57  GLU B CB  1 
ATOM   3219  C CG  . GLU B 2 41  ? 152.759 184.297 203.473 1.00 70.98  ? 57  GLU B CG  1 
ATOM   3220  C CD  . GLU B 2 41  ? 151.836 183.145 203.129 1.00 71.66  ? 57  GLU B CD  1 
ATOM   3221  O OE1 . GLU B 2 41  ? 152.028 182.044 203.686 1.00 72.68  ? 57  GLU B OE1 1 
ATOM   3222  O OE2 . GLU B 2 41  ? 150.915 183.335 202.313 1.00 73.27  ? 57  GLU B OE2 1 
ATOM   3223  N N   . GLU B 2 42  ? 153.958 187.600 202.788 1.00 76.19  ? 58  GLU B N   1 
ATOM   3224  C CA  . GLU B 2 42  ? 155.039 188.590 202.791 1.00 75.57  ? 58  GLU B CA  1 
ATOM   3225  C C   . GLU B 2 42  ? 155.741 188.668 204.151 1.00 68.40  ? 58  GLU B C   1 
ATOM   3226  O O   . GLU B 2 42  ? 155.693 189.684 204.847 1.00 68.45  ? 58  GLU B O   1 
ATOM   3227  C CB  . GLU B 2 42  ? 154.511 189.967 202.370 1.00 78.35  ? 58  GLU B CB  1 
ATOM   3228  C CG  . GLU B 2 42  ? 153.807 189.985 201.023 1.00 80.15  ? 58  GLU B CG  1 
ATOM   3229  C CD  . GLU B 2 42  ? 153.175 191.329 200.708 1.00 92.69  ? 58  GLU B CD  1 
ATOM   3230  O OE1 . GLU B 2 42  ? 153.290 192.254 201.541 1.00 93.55  ? 58  GLU B OE1 1 
ATOM   3231  O OE2 . GLU B 2 42  ? 152.563 191.462 199.627 1.00 98.88  ? 58  GLU B OE2 1 
ATOM   3232  N N   . LEU B 2 43  ? 156.402 187.575 204.523 1.00 59.99  ? 59  LEU B N   1 
ATOM   3233  C CA  . LEU B 2 43  ? 157.189 187.542 205.748 1.00 55.36  ? 59  LEU B CA  1 
ATOM   3234  C C   . LEU B 2 43  ? 158.680 187.631 205.437 1.00 49.73  ? 59  LEU B C   1 
ATOM   3235  O O   . LEU B 2 43  ? 159.111 187.569 204.284 1.00 52.22  ? 59  LEU B O   1 
ATOM   3236  C CB  . LEU B 2 43  ? 156.916 186.272 206.558 1.00 55.92  ? 59  LEU B CB  1 
ATOM   3237  C CG  . LEU B 2 43  ? 155.497 185.753 206.754 1.00 59.06  ? 59  LEU B CG  1 
ATOM   3238  C CD1 . LEU B 2 43  ? 155.281 184.556 205.860 1.00 58.45  ? 59  LEU B CD1 1 
ATOM   3239  C CD2 . LEU B 2 43  ? 155.260 185.391 208.207 1.00 59.76  ? 59  LEU B CD2 1 
ATOM   3240  N N   . PHE B 2 44  ? 159.467 187.772 206.505 1.00 44.64  ? 60  PHE B N   1 
ATOM   3241  C CA  . PHE B 2 44  ? 160.929 187.737 206.446 1.00 43.19  ? 60  PHE B CA  1 
ATOM   3242  C C   . PHE B 2 44  ? 161.498 188.819 205.534 1.00 46.05  ? 60  PHE B C   1 
ATOM   3243  O O   . PHE B 2 44  ? 162.555 188.638 204.927 1.00 43.87  ? 60  PHE B O   1 
ATOM   3244  C CB  . PHE B 2 44  ? 161.439 186.357 206.012 1.00 45.77  ? 60  PHE B CB  1 
ATOM   3245  C CG  . PHE B 2 44  ? 160.697 185.205 206.634 1.00 46.68  ? 60  PHE B CG  1 
ATOM   3246  C CD1 . PHE B 2 44  ? 160.472 185.160 207.999 1.00 45.81  ? 60  PHE B CD1 1 
ATOM   3247  C CD2 . PHE B 2 44  ? 160.239 184.159 205.853 1.00 43.98  ? 60  PHE B CD2 1 
ATOM   3248  C CE1 . PHE B 2 44  ? 159.795 184.103 208.568 1.00 45.55  ? 60  PHE B CE1 1 
ATOM   3249  C CE2 . PHE B 2 44  ? 159.563 183.100 206.419 1.00 43.19  ? 60  PHE B CE2 1 
ATOM   3250  C CZ  . PHE B 2 44  ? 159.342 183.072 207.778 1.00 44.00  ? 60  PHE B CZ  1 
ATOM   3251  N N   . ALA B 2 45  ? 160.813 189.956 205.437 1.00 46.66  ? 61  ALA B N   1 
ATOM   3252  C CA  . ALA B 2 45  ? 161.286 191.063 204.616 1.00 37.94  ? 61  ALA B CA  1 
ATOM   3253  C C   . ALA B 2 45  ? 162.412 191.784 205.345 1.00 40.47  ? 61  ALA B C   1 
ATOM   3254  O O   . ALA B 2 45  ? 162.222 192.265 206.467 1.00 44.58  ? 61  ALA B O   1 
ATOM   3255  C CB  . ALA B 2 45  ? 160.142 192.022 204.302 1.00 37.03  ? 61  ALA B CB  1 
ATOM   3256  N N   . ASP B 2 46  ? 163.580 191.865 204.710 1.00 38.15  ? 62  ASP B N   1 
ATOM   3257  C CA  . ASP B 2 46  ? 164.765 192.424 205.342 1.00 41.28  ? 62  ASP B CA  1 
ATOM   3258  C C   . ASP B 2 46  ? 165.201 193.761 204.764 1.00 49.07  ? 62  ASP B C   1 
ATOM   3259  O O   . ASP B 2 46  ? 166.065 194.415 205.357 1.00 57.01  ? 62  ASP B O   1 
ATOM   3260  C CB  . ASP B 2 46  ? 165.934 191.434 205.245 1.00 43.01  ? 62  ASP B CB  1 
ATOM   3261  C CG  . ASP B 2 46  ? 166.051 190.809 203.874 1.00 45.86  ? 62  ASP B CG  1 
ATOM   3262  O OD1 . ASP B 2 46  ? 165.451 191.351 202.925 1.00 46.08  ? 62  ASP B OD1 1 
ATOM   3263  O OD2 . ASP B 2 46  ? 166.734 189.772 203.743 1.00 48.24  ? 62  ASP B OD2 1 
ATOM   3264  N N   . VAL B 2 47  ? 164.638 194.184 203.633 1.00 49.07  ? 63  VAL B N   1 
ATOM   3265  C CA  . VAL B 2 47  ? 165.029 195.429 202.990 1.00 44.90  ? 63  VAL B CA  1 
ATOM   3266  C C   . VAL B 2 47  ? 163.775 196.208 202.615 1.00 49.81  ? 63  VAL B C   1 
ATOM   3267  O O   . VAL B 2 47  ? 162.690 195.648 202.446 1.00 48.39  ? 63  VAL B O   1 
ATOM   3268  C CB  . VAL B 2 47  ? 165.919 195.184 201.751 1.00 42.16  ? 63  VAL B CB  1 
ATOM   3269  C CG1 . VAL B 2 47  ? 165.080 194.885 200.525 1.00 40.76  ? 63  VAL B CG1 1 
ATOM   3270  C CG2 . VAL B 2 47  ? 166.827 196.366 201.509 1.00 49.87  ? 63  VAL B CG2 1 
ATOM   3271  N N   . THR B 2 48  ? 163.935 197.526 202.508 1.00 56.47  ? 64  THR B N   1 
ATOM   3272  C CA  . THR B 2 48  ? 162.851 198.425 202.134 1.00 54.12  ? 64  THR B CA  1 
ATOM   3273  C C   . THR B 2 48  ? 163.316 199.312 200.991 1.00 56.66  ? 64  THR B C   1 
ATOM   3274  O O   . THR B 2 48  ? 164.348 199.980 201.102 1.00 62.28  ? 64  THR B O   1 
ATOM   3275  C CB  . THR B 2 48  ? 162.403 199.287 203.319 1.00 57.91  ? 64  THR B CB  1 
ATOM   3276  O OG1 . THR B 2 48  ? 161.832 198.452 204.334 1.00 60.17  ? 64  THR B OG1 1 
ATOM   3277  C CG2 . THR B 2 48  ? 161.372 200.307 202.873 1.00 58.60  ? 64  THR B CG2 1 
ATOM   3278  N N   . ILE B 2 49  ? 162.554 199.320 199.901 1.00 57.56  ? 65  ILE B N   1 
ATOM   3279  C CA  . ILE B 2 49  ? 162.852 200.131 198.727 1.00 57.96  ? 65  ILE B CA  1 
ATOM   3280  C C   . ILE B 2 49  ? 161.739 201.155 198.575 1.00 58.39  ? 65  ILE B C   1 
ATOM   3281  O O   . ILE B 2 49  ? 160.561 200.788 198.480 1.00 58.15  ? 65  ILE B O   1 
ATOM   3282  C CB  . ILE B 2 49  ? 162.984 199.276 197.457 1.00 52.52  ? 65  ILE B CB  1 
ATOM   3283  C CG1 . ILE B 2 49  ? 163.878 198.060 197.716 1.00 51.04  ? 65  ILE B CG1 1 
ATOM   3284  C CG2 . ILE B 2 49  ? 163.507 200.117 196.309 1.00 52.85  ? 65  ILE B CG2 1 
ATOM   3285  C CD1 . ILE B 2 49  ? 165.341 198.283 197.409 1.00 53.62  ? 65  ILE B CD1 1 
ATOM   3286  N N   . SER B 2 50  ? 162.107 202.433 198.551 1.00 62.62  ? 66  SER B N   1 
ATOM   3287  C CA  . SER B 2 50  ? 161.153 203.528 198.434 1.00 63.45  ? 66  SER B CA  1 
ATOM   3288  C C   . SER B 2 50  ? 161.249 204.121 197.036 1.00 65.75  ? 66  SER B C   1 
ATOM   3289  O O   . SER B 2 50  ? 162.296 204.654 196.655 1.00 67.24  ? 66  SER B O   1 
ATOM   3290  C CB  . SER B 2 50  ? 161.416 204.598 199.493 1.00 65.68  ? 66  SER B CB  1 
ATOM   3291  O OG  . SER B 2 50  ? 160.276 205.417 199.683 1.00 65.90  ? 66  SER B OG  1 
ATOM   3292  N N   . VAL B 2 51  ? 160.159 204.028 196.278 1.00 63.00  ? 67  VAL B N   1 
ATOM   3293  C CA  . VAL B 2 51  ? 160.093 204.540 194.915 1.00 66.24  ? 67  VAL B CA  1 
ATOM   3294  C C   . VAL B 2 51  ? 158.897 205.475 194.816 1.00 68.40  ? 67  VAL B C   1 
ATOM   3295  O O   . VAL B 2 51  ? 157.750 205.035 194.959 1.00 68.39  ? 67  VAL B O   1 
ATOM   3296  C CB  . VAL B 2 51  ? 159.983 203.409 193.879 1.00 59.21  ? 67  VAL B CB  1 
ATOM   3297  C CG1 . VAL B 2 51  ? 159.710 203.981 192.502 1.00 58.92  ? 67  VAL B CG1 1 
ATOM   3298  C CG2 . VAL B 2 51  ? 161.251 202.576 193.869 1.00 55.83  ? 67  VAL B CG2 1 
ATOM   3299  N N   . GLU B 2 52  ? 159.165 206.758 194.564 1.00 65.79  ? 68  GLU B N   1 
ATOM   3300  C CA  . GLU B 2 52  ? 158.123 207.776 194.408 1.00 69.34  ? 68  GLU B CA  1 
ATOM   3301  C C   . GLU B 2 52  ? 157.192 207.818 195.617 1.00 70.43  ? 68  GLU B C   1 
ATOM   3302  O O   . GLU B 2 52  ? 155.974 207.956 195.487 1.00 70.71  ? 68  GLU B O   1 
ATOM   3303  C CB  . GLU B 2 52  ? 157.331 207.559 193.118 1.00 67.38  ? 68  GLU B CB  1 
ATOM   3304  C CG  . GLU B 2 52  ? 157.826 208.385 191.944 1.00 67.28  ? 68  GLU B CG  1 
ATOM   3305  C CD  . GLU B 2 52  ? 157.112 208.049 190.652 1.00 69.57  ? 68  GLU B CD  1 
ATOM   3306  O OE1 . GLU B 2 52  ? 155.983 207.519 190.715 1.00 69.07  ? 68  GLU B OE1 1 
ATOM   3307  O OE2 . GLU B 2 52  ? 157.678 208.317 189.572 1.00 72.01  ? 68  GLU B OE2 1 
ATOM   3308  N N   . GLY B 2 53  ? 157.773 207.697 196.808 1.00 67.95  ? 69  GLY B N   1 
ATOM   3309  C CA  . GLY B 2 53  ? 157.019 207.793 198.039 1.00 64.19  ? 69  GLY B CA  1 
ATOM   3310  C C   . GLY B 2 53  ? 156.325 206.526 198.484 1.00 66.91  ? 69  GLY B C   1 
ATOM   3311  O O   . GLY B 2 53  ? 155.683 206.534 199.542 1.00 70.06  ? 69  GLY B O   1 
ATOM   3312  N N   . ARG B 2 54  ? 156.426 205.441 197.723 1.00 65.69  ? 70  ARG B N   1 
ATOM   3313  C CA  . ARG B 2 54  ? 155.839 204.160 198.094 1.00 61.70  ? 70  ARG B CA  1 
ATOM   3314  C C   . ARG B 2 54  ? 156.944 203.218 198.547 1.00 62.32  ? 70  ARG B C   1 
ATOM   3315  O O   . ARG B 2 54  ? 157.955 203.064 197.854 1.00 63.75  ? 70  ARG B O   1 
ATOM   3316  C CB  . ARG B 2 54  ? 155.065 203.544 196.928 1.00 59.20  ? 70  ARG B CB  1 
ATOM   3317  C CG  . ARG B 2 54  ? 154.569 202.139 197.212 1.00 58.56  ? 70  ARG B CG  1 
ATOM   3318  C CD  . ARG B 2 54  ? 153.498 201.700 196.230 1.00 57.36  ? 70  ARG B CD  1 
ATOM   3319  N NE  . ARG B 2 54  ? 153.158 200.294 196.407 1.00 59.58  ? 70  ARG B NE  1 
ATOM   3320  C CZ  . ARG B 2 54  ? 152.444 199.579 195.549 1.00 60.42  ? 70  ARG B CZ  1 
ATOM   3321  N NH1 . ARG B 2 54  ? 151.970 200.110 194.434 1.00 60.13  ? 70  ARG B NH1 1 
ATOM   3322  N NH2 . ARG B 2 54  ? 152.199 198.300 195.815 1.00 59.14  ? 70  ARG B NH2 1 
ATOM   3323  N N   . GLU B 2 55  ? 156.749 202.591 199.702 1.00 61.52  ? 71  GLU B N   1 
ATOM   3324  C CA  . GLU B 2 55  ? 157.740 201.702 200.290 1.00 58.87  ? 71  GLU B CA  1 
ATOM   3325  C C   . GLU B 2 55  ? 157.435 200.260 199.907 1.00 58.14  ? 71  GLU B C   1 
ATOM   3326  O O   . GLU B 2 55  ? 156.301 199.796 200.066 1.00 57.68  ? 71  GLU B O   1 
ATOM   3327  C CB  . GLU B 2 55  ? 157.767 201.848 201.812 1.00 60.28  ? 71  GLU B CB  1 
ATOM   3328  C CG  . GLU B 2 55  ? 158.006 203.267 202.295 1.00 68.12  ? 71  GLU B CG  1 
ATOM   3329  C CD  . GLU B 2 55  ? 159.102 203.351 203.339 1.00 74.76  ? 71  GLU B CD  1 
ATOM   3330  O OE1 . GLU B 2 55  ? 160.286 203.447 202.952 1.00 71.90  ? 71  GLU B OE1 1 
ATOM   3331  O OE2 . GLU B 2 55  ? 158.782 203.319 204.545 1.00 76.48  ? 71  GLU B OE2 1 
ATOM   3332  N N   . PHE B 2 56  ? 158.446 199.562 199.399 1.00 55.54  ? 72  PHE B N   1 
ATOM   3333  C CA  . PHE B 2 56  ? 158.345 198.150 199.053 1.00 50.68  ? 72  PHE B CA  1 
ATOM   3334  C C   . PHE B 2 56  ? 159.166 197.351 200.054 1.00 53.48  ? 72  PHE B C   1 
ATOM   3335  O O   . PHE B 2 56  ? 160.369 197.590 200.203 1.00 55.93  ? 72  PHE B O   1 
ATOM   3336  C CB  . PHE B 2 56  ? 158.841 197.891 197.630 1.00 49.04  ? 72  PHE B CB  1 
ATOM   3337  C CG  . PHE B 2 56  ? 157.962 198.471 196.559 1.00 52.74  ? 72  PHE B CG  1 
ATOM   3338  C CD1 . PHE B 2 56  ? 158.038 199.814 196.231 1.00 51.90  ? 72  PHE B CD1 1 
ATOM   3339  C CD2 . PHE B 2 56  ? 157.068 197.670 195.869 1.00 53.51  ? 72  PHE B CD2 1 
ATOM   3340  C CE1 . PHE B 2 56  ? 157.234 200.346 195.244 1.00 50.56  ? 72  PHE B CE1 1 
ATOM   3341  C CE2 . PHE B 2 56  ? 156.263 198.198 194.882 1.00 49.76  ? 72  PHE B CE2 1 
ATOM   3342  C CZ  . PHE B 2 56  ? 156.346 199.537 194.570 1.00 50.09  ? 72  PHE B CZ  1 
ATOM   3343  N N   . GLN B 2 57  ? 158.520 196.409 200.737 1.00 51.84  ? 73  GLN B N   1 
ATOM   3344  C CA  . GLN B 2 57  ? 159.199 195.525 201.682 1.00 48.45  ? 73  GLN B CA  1 
ATOM   3345  C C   . GLN B 2 57  ? 159.645 194.286 200.916 1.00 48.45  ? 73  GLN B C   1 
ATOM   3346  O O   . GLN B 2 57  ? 158.838 193.403 200.617 1.00 49.23  ? 73  GLN B O   1 
ATOM   3347  C CB  . GLN B 2 57  ? 158.284 195.171 202.847 1.00 50.28  ? 73  GLN B CB  1 
ATOM   3348  C CG  . GLN B 2 57  ? 158.594 195.926 204.128 1.00 53.01  ? 73  GLN B CG  1 
ATOM   3349  C CD  . GLN B 2 57  ? 158.046 197.337 204.119 1.00 60.19  ? 73  GLN B CD  1 
ATOM   3350  O OE1 . GLN B 2 57  ? 156.833 197.544 204.112 1.00 61.78  ? 73  GLN B OE1 1 
ATOM   3351  N NE2 . GLN B 2 57  ? 158.939 198.319 204.122 1.00 59.59  ? 73  GLN B NE2 1 
ATOM   3352  N N   . LEU B 2 58  ? 160.933 194.217 200.602 1.00 43.39  ? 74  LEU B N   1 
ATOM   3353  C CA  . LEU B 2 58  ? 161.470 193.205 199.707 1.00 39.99  ? 74  LEU B CA  1 
ATOM   3354  C C   . LEU B 2 58  ? 162.484 192.334 200.436 1.00 39.21  ? 74  LEU B C   1 
ATOM   3355  O O   . LEU B 2 58  ? 162.908 192.629 201.555 1.00 41.98  ? 74  LEU B O   1 
ATOM   3356  C CB  . LEU B 2 58  ? 162.119 193.854 198.477 1.00 41.84  ? 74  LEU B CB  1 
ATOM   3357  C CG  . LEU B 2 58  ? 161.206 194.665 197.556 1.00 38.70  ? 74  LEU B CG  1 
ATOM   3358  C CD1 . LEU B 2 58  ? 161.973 195.141 196.342 1.00 38.19  ? 74  LEU B CD1 1 
ATOM   3359  C CD2 . LEU B 2 58  ? 159.997 193.851 197.139 1.00 38.07  ? 74  LEU B CD2 1 
ATOM   3360  N N   . HIS B 2 59  ? 162.864 191.243 199.779 1.00 37.68  ? 75  HIS B N   1 
ATOM   3361  C CA  . HIS B 2 59  ? 163.871 190.316 200.277 1.00 35.14  ? 75  HIS B CA  1 
ATOM   3362  C C   . HIS B 2 59  ? 165.118 190.465 199.421 1.00 33.41  ? 75  HIS B C   1 
ATOM   3363  O O   . HIS B 2 59  ? 165.054 190.312 198.198 1.00 35.85  ? 75  HIS B O   1 
ATOM   3364  C CB  . HIS B 2 59  ? 163.363 188.874 200.236 1.00 35.72  ? 75  HIS B CB  1 
ATOM   3365  C CG  . HIS B 2 59  ? 162.028 188.682 200.883 1.00 37.14  ? 75  HIS B CG  1 
ATOM   3366  N ND1 . HIS B 2 59  ? 160.846 189.039 200.273 1.00 38.30  ? 75  HIS B ND1 1 
ATOM   3367  C CD2 . HIS B 2 59  ? 161.687 188.160 202.084 1.00 36.84  ? 75  HIS B CD2 1 
ATOM   3368  C CE1 . HIS B 2 59  ? 159.835 188.753 201.073 1.00 39.06  ? 75  HIS B CE1 1 
ATOM   3369  N NE2 . HIS B 2 59  ? 160.319 188.217 202.178 1.00 40.41  ? 75  HIS B NE2 1 
ATOM   3370  N N   . ARG B 2 60  ? 166.251 190.759 200.061 1.00 32.30  ? 76  ARG B N   1 
ATOM   3371  C CA  . ARG B 2 60  ? 167.477 190.977 199.305 1.00 34.46  ? 76  ARG B CA  1 
ATOM   3372  C C   . ARG B 2 60  ? 168.039 189.688 198.727 1.00 35.23  ? 76  ARG B C   1 
ATOM   3373  O O   . ARG B 2 60  ? 168.835 189.745 197.784 1.00 36.74  ? 76  ARG B O   1 
ATOM   3374  C CB  . ARG B 2 60  ? 168.523 191.666 200.180 1.00 36.35  ? 76  ARG B CB  1 
ATOM   3375  C CG  . ARG B 2 60  ? 168.804 190.972 201.485 1.00 38.90  ? 76  ARG B CG  1 
ATOM   3376  C CD  . ARG B 2 60  ? 169.104 191.978 202.577 1.00 43.86  ? 76  ARG B CD  1 
ATOM   3377  N NE  . ARG B 2 60  ? 170.437 192.548 202.439 1.00 49.22  ? 76  ARG B NE  1 
ATOM   3378  C CZ  . ARG B 2 60  ? 171.297 192.686 203.438 1.00 54.25  ? 76  ARG B CZ  1 
ATOM   3379  N NH1 . ARG B 2 60  ? 171.000 192.290 204.665 1.00 49.14  ? 76  ARG B NH1 1 
ATOM   3380  N NH2 . ARG B 2 60  ? 172.485 193.234 203.200 1.00 56.06  ? 76  ARG B NH2 1 
ATOM   3381  N N   . LEU B 2 61  ? 167.635 188.533 199.256 1.00 38.35  ? 77  LEU B N   1 
ATOM   3382  C CA  . LEU B 2 61  ? 168.089 187.261 198.704 1.00 34.70  ? 77  LEU B CA  1 
ATOM   3383  C C   . LEU B 2 61  ? 167.577 187.069 197.281 1.00 34.54  ? 77  LEU B C   1 
ATOM   3384  O O   . LEU B 2 61  ? 168.349 186.761 196.366 1.00 37.15  ? 77  LEU B O   1 
ATOM   3385  C CB  . LEU B 2 61  ? 167.633 186.115 199.609 1.00 35.41  ? 77  LEU B CB  1 
ATOM   3386  C CG  . LEU B 2 61  ? 168.097 184.695 199.285 1.00 38.55  ? 77  LEU B CG  1 
ATOM   3387  C CD1 . LEU B 2 61  ? 169.521 184.476 199.759 1.00 44.42  ? 77  LEU B CD1 1 
ATOM   3388  C CD2 . LEU B 2 61  ? 167.160 183.680 199.914 1.00 34.54  ? 77  LEU B CD2 1 
ATOM   3389  N N   . VAL B 2 62  ? 166.274 187.271 197.071 1.00 31.88  ? 78  VAL B N   1 
ATOM   3390  C CA  . VAL B 2 62  ? 165.693 187.128 195.739 1.00 30.36  ? 78  VAL B CA  1 
ATOM   3391  C C   . VAL B 2 62  ? 166.232 188.198 194.799 1.00 32.12  ? 78  VAL B C   1 
ATOM   3392  O O   . VAL B 2 62  ? 166.559 187.921 193.636 1.00 33.71  ? 78  VAL B O   1 
ATOM   3393  C CB  . VAL B 2 62  ? 164.158 187.174 195.823 1.00 31.38  ? 78  VAL B CB  1 
ATOM   3394  C CG1 . VAL B 2 62  ? 163.539 186.660 194.533 1.00 34.56  ? 78  VAL B CG1 1 
ATOM   3395  C CG2 . VAL B 2 62  ? 163.668 186.372 197.017 1.00 31.02  ? 78  VAL B CG2 1 
ATOM   3396  N N   . LEU B 2 63  ? 166.329 189.437 195.284 1.00 33.30  ? 79  LEU B N   1 
ATOM   3397  C CA  . LEU B 2 63  ? 166.826 190.529 194.454 1.00 33.65  ? 79  LEU B CA  1 
ATOM   3398  C C   . LEU B 2 63  ? 168.253 190.266 193.994 1.00 34.81  ? 79  LEU B C   1 
ATOM   3399  O O   . LEU B 2 63  ? 168.589 190.502 192.828 1.00 38.28  ? 79  LEU B O   1 
ATOM   3400  C CB  . LEU B 2 63  ? 166.750 191.846 195.226 1.00 32.06  ? 79  LEU B CB  1 
ATOM   3401  C CG  . LEU B 2 63  ? 165.489 192.707 195.119 1.00 29.51  ? 79  LEU B CG  1 
ATOM   3402  C CD1 . LEU B 2 63  ? 164.231 191.865 195.142 1.00 27.45  ? 79  LEU B CD1 1 
ATOM   3403  C CD2 . LEU B 2 63  ? 165.467 193.722 196.245 1.00 32.17  ? 79  LEU B CD2 1 
ATOM   3404  N N   . SER B 2 64  ? 169.107 189.776 194.894 1.00 33.50  ? 80  SER B N   1 
ATOM   3405  C CA  . SER B 2 64  ? 170.485 189.482 194.523 1.00 34.18  ? 80  SER B CA  1 
ATOM   3406  C C   . SER B 2 64  ? 170.583 188.242 193.646 1.00 36.10  ? 80  SER B C   1 
ATOM   3407  O O   . SER B 2 64  ? 171.483 188.152 192.805 1.00 39.65  ? 80  SER B O   1 
ATOM   3408  C CB  . SER B 2 64  ? 171.337 189.316 195.777 1.00 36.92  ? 80  SER B CB  1 
ATOM   3409  O OG  . SER B 2 64  ? 171.155 190.407 196.658 1.00 40.97  ? 80  SER B OG  1 
ATOM   3410  N N   . ALA B 2 65  ? 169.680 187.276 193.826 1.00 34.54  ? 81  ALA B N   1 
ATOM   3411  C CA  . ALA B 2 65  ? 169.680 186.089 192.983 1.00 34.65  ? 81  ALA B CA  1 
ATOM   3412  C C   . ALA B 2 65  ? 169.163 186.364 191.579 1.00 35.68  ? 81  ALA B C   1 
ATOM   3413  O O   . ALA B 2 65  ? 169.458 185.589 190.664 1.00 33.00  ? 81  ALA B O   1 
ATOM   3414  C CB  . ALA B 2 65  ? 168.840 184.986 193.626 1.00 33.40  ? 81  ALA B CB  1 
ATOM   3415  N N   . GLN B 2 66  ? 168.402 187.440 191.387 1.00 39.47  ? 82  GLN B N   1 
ATOM   3416  C CA  . GLN B 2 66  ? 167.808 187.728 190.087 1.00 35.50  ? 82  GLN B CA  1 
ATOM   3417  C C   . GLN B 2 66  ? 168.586 188.743 189.263 1.00 34.72  ? 82  GLN B C   1 
ATOM   3418  O O   . GLN B 2 66  ? 168.447 188.756 188.036 1.00 35.87  ? 82  GLN B O   1 
ATOM   3419  C CB  . GLN B 2 66  ? 166.371 188.226 190.264 1.00 31.69  ? 82  GLN B CB  1 
ATOM   3420  C CG  . GLN B 2 66  ? 165.376 187.114 190.517 1.00 28.12  ? 82  GLN B CG  1 
ATOM   3421  C CD  . GLN B 2 66  ? 165.013 186.374 189.251 1.00 30.80  ? 82  GLN B CD  1 
ATOM   3422  O OE1 . GLN B 2 66  ? 164.702 185.187 189.281 1.00 32.56  ? 82  GLN B OE1 1 
ATOM   3423  N NE2 . GLN B 2 66  ? 165.044 187.076 188.128 1.00 34.47  ? 82  GLN B NE2 1 
ATOM   3424  N N   . SER B 2 67  ? 169.397 189.592 189.889 1.00 35.91  ? 83  SER B N   1 
ATOM   3425  C CA  . SER B 2 67  ? 170.097 190.635 189.155 1.00 37.44  ? 83  SER B CA  1 
ATOM   3426  C C   . SER B 2 67  ? 171.431 190.936 189.821 1.00 41.82  ? 83  SER B C   1 
ATOM   3427  O O   . SER B 2 67  ? 171.543 190.895 191.048 1.00 40.19  ? 83  SER B O   1 
ATOM   3428  C CB  . SER B 2 67  ? 169.252 191.909 189.072 1.00 34.41  ? 83  SER B CB  1 
ATOM   3429  O OG  . SER B 2 67  ? 169.230 192.583 190.315 1.00 35.31  ? 83  SER B OG  1 
ATOM   3430  N N   . CYS B 2 68  ? 172.437 191.241 188.999 1.00 42.41  ? 84  CYS B N   1 
ATOM   3431  C CA  . CYS B 2 68  ? 173.743 191.634 189.511 1.00 42.39  ? 84  CYS B CA  1 
ATOM   3432  C C   . CYS B 2 68  ? 173.762 193.064 190.033 1.00 43.57  ? 84  CYS B C   1 
ATOM   3433  O O   . CYS B 2 68  ? 174.610 193.391 190.870 1.00 47.44  ? 84  CYS B O   1 
ATOM   3434  C CB  . CYS B 2 68  ? 174.809 191.474 188.425 1.00 43.48  ? 84  CYS B CB  1 
ATOM   3435  S SG  . CYS B 2 68  ? 174.547 190.071 187.317 1.00 60.05  ? 84  CYS B SG  1 
ATOM   3436  N N   . PHE B 2 69  ? 172.851 193.916 189.559 1.00 39.53  ? 85  PHE B N   1 
ATOM   3437  C CA  . PHE B 2 69  ? 172.770 195.283 190.066 1.00 36.12  ? 85  PHE B CA  1 
ATOM   3438  C C   . PHE B 2 69  ? 172.441 195.294 191.552 1.00 39.55  ? 85  PHE B C   1 
ATOM   3439  O O   . PHE B 2 69  ? 173.158 195.899 192.358 1.00 42.83  ? 85  PHE B O   1 
ATOM   3440  C CB  . PHE B 2 69  ? 171.721 196.061 189.269 1.00 34.27  ? 85  PHE B CB  1 
ATOM   3441  C CG  . PHE B 2 69  ? 171.436 197.435 189.803 1.00 33.26  ? 85  PHE B CG  1 
ATOM   3442  C CD1 . PHE B 2 69  ? 172.243 198.505 189.463 1.00 34.49  ? 85  PHE B CD1 1 
ATOM   3443  C CD2 . PHE B 2 69  ? 170.345 197.662 190.622 1.00 32.55  ? 85  PHE B CD2 1 
ATOM   3444  C CE1 . PHE B 2 69  ? 171.978 199.769 189.945 1.00 35.10  ? 85  PHE B CE1 1 
ATOM   3445  C CE2 . PHE B 2 69  ? 170.076 198.923 191.106 1.00 33.80  ? 85  PHE B CE2 1 
ATOM   3446  C CZ  . PHE B 2 69  ? 170.893 199.978 190.766 1.00 35.44  ? 85  PHE B CZ  1 
ATOM   3447  N N   . PHE B 2 70  ? 171.369 194.599 191.940 1.00 39.59  ? 86  PHE B N   1 
ATOM   3448  C CA  . PHE B 2 70  ? 171.002 194.533 193.349 1.00 36.50  ? 86  PHE B CA  1 
ATOM   3449  C C   . PHE B 2 70  ? 172.011 193.726 194.152 1.00 41.06  ? 86  PHE B C   1 
ATOM   3450  O O   . PHE B 2 70  ? 172.244 194.026 195.326 1.00 45.29  ? 86  PHE B O   1 
ATOM   3451  C CB  . PHE B 2 70  ? 169.603 193.942 193.503 1.00 34.45  ? 86  PHE B CB  1 
ATOM   3452  C CG  . PHE B 2 70  ? 168.501 194.887 193.121 1.00 36.86  ? 86  PHE B CG  1 
ATOM   3453  C CD1 . PHE B 2 70  ? 168.323 196.076 193.805 1.00 38.28  ? 86  PHE B CD1 1 
ATOM   3454  C CD2 . PHE B 2 70  ? 167.642 194.585 192.079 1.00 33.62  ? 86  PHE B CD2 1 
ATOM   3455  C CE1 . PHE B 2 70  ? 167.310 196.944 193.455 1.00 36.58  ? 86  PHE B CE1 1 
ATOM   3456  C CE2 . PHE B 2 70  ? 166.629 195.450 191.726 1.00 31.14  ? 86  PHE B CE2 1 
ATOM   3457  C CZ  . PHE B 2 70  ? 166.463 196.630 192.415 1.00 34.18  ? 86  PHE B CZ  1 
ATOM   3458  N N   . ARG B 2 71  ? 172.620 192.707 193.544 1.00 41.21  ? 87  ARG B N   1 
ATOM   3459  C CA  . ARG B 2 71  ? 173.637 191.937 194.252 1.00 42.54  ? 87  ARG B CA  1 
ATOM   3460  C C   . ARG B 2 71  ? 174.831 192.809 194.617 1.00 47.20  ? 87  ARG B C   1 
ATOM   3461  O O   . ARG B 2 71  ? 175.343 192.733 195.738 1.00 50.56  ? 87  ARG B O   1 
ATOM   3462  C CB  . ARG B 2 71  ? 174.081 190.746 193.405 1.00 43.41  ? 87  ARG B CB  1 
ATOM   3463  C CG  . ARG B 2 71  ? 175.200 189.929 194.025 1.00 45.27  ? 87  ARG B CG  1 
ATOM   3464  C CD  . ARG B 2 71  ? 175.655 188.824 193.088 1.00 48.00  ? 87  ARG B CD  1 
ATOM   3465  N NE  . ARG B 2 71  ? 174.531 188.193 192.406 1.00 53.17  ? 87  ARG B NE  1 
ATOM   3466  C CZ  . ARG B 2 71  ? 174.578 187.712 191.172 1.00 53.32  ? 87  ARG B CZ  1 
ATOM   3467  N NH1 . ARG B 2 71  ? 175.684 187.772 190.448 1.00 55.69  ? 87  ARG B NH1 1 
ATOM   3468  N NH2 . ARG B 2 71  ? 173.488 187.158 190.649 1.00 46.46  ? 87  ARG B NH2 1 
ATOM   3469  N N   . SER B 2 72  ? 175.284 193.652 193.686 1.00 49.38  ? 88  SER B N   1 
ATOM   3470  C CA  . SER B 2 72  ? 176.388 194.556 193.987 1.00 49.61  ? 88  SER B CA  1 
ATOM   3471  C C   . SER B 2 72  ? 175.952 195.694 194.899 1.00 51.31  ? 88  SER B C   1 
ATOM   3472  O O   . SER B 2 72  ? 176.773 196.235 195.647 1.00 55.38  ? 88  SER B O   1 
ATOM   3473  C CB  . SER B 2 72  ? 176.980 195.108 192.692 1.00 49.64  ? 88  SER B CB  1 
ATOM   3474  O OG  . SER B 2 72  ? 177.538 194.070 191.907 1.00 52.26  ? 88  SER B OG  1 
ATOM   3475  N N   . MET B 2 73  ? 174.675 196.079 194.846 1.00 49.45  ? 89  MET B N   1 
ATOM   3476  C CA  . MET B 2 73  ? 174.173 197.098 195.762 1.00 49.77  ? 89  MET B CA  1 
ATOM   3477  C C   . MET B 2 73  ? 174.150 196.592 197.199 1.00 56.73  ? 89  MET B C   1 
ATOM   3478  O O   . MET B 2 73  ? 174.476 197.336 198.131 1.00 65.59  ? 89  MET B O   1 
ATOM   3479  C CB  . MET B 2 73  ? 172.778 197.545 195.325 1.00 49.56  ? 89  MET B CB  1 
ATOM   3480  C CG  . MET B 2 73  ? 171.975 198.247 196.403 1.00 55.09  ? 89  MET B CG  1 
ATOM   3481  S SD  . MET B 2 73  ? 170.526 199.093 195.747 1.00 80.50  ? 89  MET B SD  1 
ATOM   3482  C CE  . MET B 2 73  ? 171.247 199.981 194.371 1.00 58.21  ? 89  MET B CE  1 
ATOM   3483  N N   . PHE B 2 74  ? 173.774 195.330 197.398 1.00 54.27  ? 90  PHE B N   1 
ATOM   3484  C CA  . PHE B 2 74  ? 173.624 194.762 198.732 1.00 53.06  ? 90  PHE B CA  1 
ATOM   3485  C C   . PHE B 2 74  ? 174.947 194.250 199.293 1.00 58.74  ? 90  PHE B C   1 
ATOM   3486  O O   . PHE B 2 74  ? 175.308 194.574 200.429 1.00 61.61  ? 90  PHE B O   1 
ATOM   3487  C CB  . PHE B 2 74  ? 172.589 193.634 198.702 1.00 47.55  ? 90  PHE B CB  1 
ATOM   3488  C CG  . PHE B 2 74  ? 171.187 194.107 198.450 1.00 47.25  ? 90  PHE B CG  1 
ATOM   3489  C CD1 . PHE B 2 74  ? 170.724 195.276 199.025 1.00 48.52  ? 90  PHE B CD1 1 
ATOM   3490  C CD2 . PHE B 2 74  ? 170.335 193.387 197.634 1.00 42.12  ? 90  PHE B CD2 1 
ATOM   3491  C CE1 . PHE B 2 74  ? 169.439 195.714 198.795 1.00 44.71  ? 90  PHE B CE1 1 
ATOM   3492  C CE2 . PHE B 2 74  ? 169.049 193.822 197.400 1.00 39.41  ? 90  PHE B CE2 1 
ATOM   3493  C CZ  . PHE B 2 74  ? 168.601 194.985 197.982 1.00 41.44  ? 90  PHE B CZ  1 
ATOM   3494  N N   . THR B 2 75  ? 175.672 193.444 198.517 1.00 60.00  ? 91  THR B N   1 
ATOM   3495  C CA  . THR B 2 75  ? 176.968 192.941 198.959 1.00 61.62  ? 91  THR B CA  1 
ATOM   3496  C C   . THR B 2 75  ? 177.949 194.086 199.179 1.00 67.09  ? 91  THR B C   1 
ATOM   3497  O O   . THR B 2 75  ? 178.435 194.302 200.295 1.00 72.72  ? 91  THR B O   1 
ATOM   3498  C CB  . THR B 2 75  ? 177.516 191.947 197.933 1.00 56.29  ? 91  THR B CB  1 
ATOM   3499  O OG1 . THR B 2 75  ? 176.734 190.747 197.964 1.00 53.17  ? 91  THR B OG1 1 
ATOM   3500  C CG2 . THR B 2 75  ? 178.965 191.606 198.240 1.00 62.24  ? 91  THR B CG2 1 
ATOM   3501  N N   . SER B 2 76  ? 178.246 194.839 198.120 1.00 65.99  ? 92  SER B N   1 
ATOM   3502  C CA  . SER B 2 76  ? 179.110 196.015 198.217 1.00 72.92  ? 92  SER B CA  1 
ATOM   3503  C C   . SER B 2 76  ? 178.254 197.188 198.686 1.00 76.77  ? 92  SER B C   1 
ATOM   3504  O O   . SER B 2 76  ? 177.802 198.031 197.908 1.00 78.41  ? 92  SER B O   1 
ATOM   3505  C CB  . SER B 2 76  ? 179.786 196.302 196.882 1.00 74.00  ? 92  SER B CB  1 
ATOM   3506  O OG  . SER B 2 76  ? 180.292 197.624 196.840 1.00 81.48  ? 92  SER B OG  1 
ATOM   3507  N N   . ASN B 2 77  ? 178.031 197.232 199.996 1.00 79.48  ? 93  ASN B N   1 
ATOM   3508  C CA  . ASN B 2 77  ? 177.137 198.220 200.577 1.00 86.74  ? 93  ASN B CA  1 
ATOM   3509  C C   . ASN B 2 77  ? 177.745 199.619 200.509 1.00 94.35  ? 93  ASN B C   1 
ATOM   3510  O O   . ASN B 2 77  ? 178.965 199.801 200.467 1.00 91.81  ? 93  ASN B O   1 
ATOM   3511  C CB  . ASN B 2 77  ? 176.814 197.862 202.027 1.00 91.64  ? 93  ASN B CB  1 
ATOM   3512  C CG  . ASN B 2 77  ? 178.030 197.376 202.793 1.00 94.15  ? 93  ASN B CG  1 
ATOM   3513  O OD1 . ASN B 2 77  ? 178.291 196.176 202.871 1.00 89.63  ? 93  ASN B OD1 1 
ATOM   3514  N ND2 . ASN B 2 77  ? 178.780 198.310 203.366 1.00 96.92  ? 93  ASN B ND2 1 
ATOM   3515  N N   . LEU B 2 78  ? 176.863 200.617 200.499 1.00 100.64 ? 94  LEU B N   1 
ATOM   3516  C CA  . LEU B 2 78  ? 177.265 202.018 200.476 1.00 101.64 ? 94  LEU B CA  1 
ATOM   3517  C C   . LEU B 2 78  ? 176.524 202.790 201.559 1.00 106.65 ? 94  LEU B C   1 
ATOM   3518  O O   . LEU B 2 78  ? 175.846 202.190 202.399 1.00 107.77 ? 94  LEU B O   1 
ATOM   3519  C CB  . LEU B 2 78  ? 176.999 202.633 199.102 1.00 102.05 ? 94  LEU B CB  1 
ATOM   3520  C CG  . LEU B 2 78  ? 177.846 202.108 197.941 1.00 100.65 ? 94  LEU B CG  1 
ATOM   3521  C CD1 . LEU B 2 78  ? 177.036 201.155 197.076 1.00 94.26  ? 94  LEU B CD1 1 
ATOM   3522  C CD2 . LEU B 2 78  ? 178.392 203.260 197.112 1.00 98.01  ? 94  LEU B CD2 1 
ATOM   3523  N N   . LYS B 2 79  ? 176.650 204.118 201.556 1.00 109.95 ? 95  LYS B N   1 
ATOM   3524  C CA  . LYS B 2 79  ? 175.945 204.929 202.545 1.00 112.65 ? 95  LYS B CA  1 
ATOM   3525  C C   . LYS B 2 79  ? 174.435 204.852 202.347 1.00 110.67 ? 95  LYS B C   1 
ATOM   3526  O O   . LYS B 2 79  ? 173.680 204.678 203.311 1.00 106.72 ? 95  LYS B O   1 
ATOM   3527  C CB  . LYS B 2 79  ? 176.425 206.379 202.474 1.00 112.67 ? 95  LYS B CB  1 
ATOM   3528  C CG  . LYS B 2 79  ? 176.559 207.057 203.828 1.00 113.87 ? 95  LYS B CG  1 
ATOM   3529  C CD  . LYS B 2 79  ? 177.486 206.281 204.752 1.00 114.17 ? 95  LYS B CD  1 
ATOM   3530  C CE  . LYS B 2 79  ? 178.907 206.246 204.211 1.00 115.00 ? 95  LYS B CE  1 
ATOM   3531  N NZ  . LYS B 2 79  ? 179.542 207.592 204.232 1.00 114.64 ? 95  LYS B NZ  1 
ATOM   3532  N N   . GLU B 2 80  ? 173.977 204.978 201.101 1.00 111.49 ? 96  GLU B N   1 
ATOM   3533  C CA  . GLU B 2 80  ? 172.547 204.943 200.818 1.00 108.32 ? 96  GLU B CA  1 
ATOM   3534  C C   . GLU B 2 80  ? 171.964 203.542 200.957 1.00 106.03 ? 96  GLU B C   1 
ATOM   3535  O O   . GLU B 2 80  ? 170.837 203.390 201.441 1.00 101.13 ? 96  GLU B O   1 
ATOM   3536  C CB  . GLU B 2 80  ? 172.280 205.484 199.410 1.00 105.64 ? 96  GLU B CB  1 
ATOM   3537  C CG  . GLU B 2 80  ? 170.936 205.081 198.820 1.00 101.43 ? 96  GLU B CG  1 
ATOM   3538  C CD  . GLU B 2 80  ? 171.016 204.774 197.337 1.00 102.77 ? 96  GLU B CD  1 
ATOM   3539  O OE1 . GLU B 2 80  ? 171.322 203.616 196.984 1.00 99.54  ? 96  GLU B OE1 1 
ATOM   3540  O OE2 . GLU B 2 80  ? 170.773 205.690 196.524 1.00 101.65 ? 96  GLU B OE2 1 
ATOM   3541  N N   . ALA B 2 81  ? 172.712 202.516 200.563 1.00 105.78 ? 97  ALA B N   1 
ATOM   3542  C CA  . ALA B 2 81  ? 172.192 201.159 200.470 1.00 104.32 ? 97  ALA B CA  1 
ATOM   3543  C C   . ALA B 2 81  ? 172.327 200.369 201.766 1.00 106.45 ? 97  ALA B C   1 
ATOM   3544  O O   . ALA B 2 81  ? 172.009 199.176 201.781 1.00 103.32 ? 97  ALA B O   1 
ATOM   3545  C CB  . ALA B 2 81  ? 172.891 200.407 199.334 1.00 95.93  ? 97  ALA B CB  1 
ATOM   3546  N N   . HIS B 2 82  ? 172.784 200.995 202.850 1.00 107.61 ? 98  HIS B N   1 
ATOM   3547  C CA  . HIS B 2 82  ? 173.029 200.254 204.078 1.00 106.88 ? 98  HIS B CA  1 
ATOM   3548  C C   . HIS B 2 82  ? 172.505 200.917 205.345 1.00 106.41 ? 98  HIS B C   1 
ATOM   3549  O O   . HIS B 2 82  ? 172.631 200.317 206.417 1.00 102.68 ? 98  HIS B O   1 
ATOM   3550  C CB  . HIS B 2 82  ? 174.537 199.990 204.243 1.00 104.61 ? 98  HIS B CB  1 
ATOM   3551  C CG  . HIS B 2 82  ? 174.856 198.764 205.041 1.00 105.89 ? 98  HIS B CG  1 
ATOM   3552  N ND1 . HIS B 2 82  ? 174.734 197.490 204.530 1.00 103.49 ? 98  HIS B ND1 1 
ATOM   3553  C CD2 . HIS B 2 82  ? 175.301 198.619 206.311 1.00 106.34 ? 98  HIS B CD2 1 
ATOM   3554  C CE1 . HIS B 2 82  ? 175.087 196.612 205.453 1.00 102.63 ? 98  HIS B CE1 1 
ATOM   3555  N NE2 . HIS B 2 82  ? 175.435 197.272 206.543 1.00 106.67 ? 98  HIS B NE2 1 
ATOM   3556  N N   . ASN B 2 83  ? 171.923 202.116 205.276 1.00 107.65 ? 99  ASN B N   1 
ATOM   3557  C CA  . ASN B 2 83  ? 171.509 202.769 206.518 1.00 106.93 ? 99  ASN B CA  1 
ATOM   3558  C C   . ASN B 2 83  ? 170.183 202.204 207.023 1.00 104.62 ? 99  ASN B C   1 
ATOM   3559  O O   . ASN B 2 83  ? 170.142 201.507 208.041 1.00 102.54 ? 99  ASN B O   1 
ATOM   3560  C CB  . ASN B 2 83  ? 171.420 204.284 206.309 1.00 105.81 ? 99  ASN B CB  1 
ATOM   3561  C CG  . ASN B 2 83  ? 170.807 204.654 204.973 1.00 105.30 ? 99  ASN B CG  1 
ATOM   3562  O OD1 . ASN B 2 83  ? 170.380 203.785 204.213 1.00 104.74 ? 99  ASN B OD1 1 
ATOM   3563  N ND2 . ASN B 2 83  ? 170.761 205.948 204.679 1.00 104.00 ? 99  ASN B ND2 1 
ATOM   3564  N N   . ARG B 2 84  ? 169.084 202.492 206.324 1.00 100.12 ? 100 ARG B N   1 
ATOM   3565  C CA  . ARG B 2 84  ? 167.846 201.760 206.565 1.00 96.91  ? 100 ARG B CA  1 
ATOM   3566  C C   . ARG B 2 84  ? 167.138 201.370 205.273 1.00 92.82  ? 100 ARG B C   1 
ATOM   3567  O O   . ARG B 2 84  ? 166.608 200.260 205.158 1.00 90.83  ? 100 ARG B O   1 
ATOM   3568  C CB  . ARG B 2 84  ? 166.902 202.574 207.452 1.00 97.34  ? 100 ARG B CB  1 
ATOM   3569  C CG  . ARG B 2 84  ? 166.852 202.102 208.902 1.00 99.77  ? 100 ARG B CG  1 
ATOM   3570  C CD  . ARG B 2 84  ? 166.985 200.585 209.011 1.00 98.21  ? 100 ARG B CD  1 
ATOM   3571  N NE  . ARG B 2 84  ? 165.905 199.876 208.334 1.00 99.88  ? 100 ARG B NE  1 
ATOM   3572  C CZ  . ARG B 2 84  ? 166.016 198.660 207.816 1.00 97.42  ? 100 ARG B CZ  1 
ATOM   3573  N NH1 . ARG B 2 84  ? 167.151 197.983 207.880 1.00 94.39  ? 100 ARG B NH1 1 
ATOM   3574  N NH2 . ARG B 2 84  ? 164.964 198.111 207.217 1.00 88.28  ? 100 ARG B NH2 1 
ATOM   3575  N N   . VAL B 2 85  ? 167.128 202.278 204.294 1.00 90.69  ? 101 VAL B N   1 
ATOM   3576  C CA  . VAL B 2 85  ? 166.307 202.136 203.098 1.00 85.56  ? 101 VAL B CA  1 
ATOM   3577  C C   . VAL B 2 85  ? 167.115 202.543 201.874 1.00 84.37  ? 101 VAL B C   1 
ATOM   3578  O O   . VAL B 2 85  ? 168.122 203.247 201.968 1.00 87.67  ? 101 VAL B O   1 
ATOM   3579  C CB  . VAL B 2 85  ? 165.011 202.978 203.168 1.00 79.64  ? 101 VAL B CB  1 
ATOM   3580  C CG1 . VAL B 2 85  ? 164.138 202.537 204.332 1.00 77.26  ? 101 VAL B CG1 1 
ATOM   3581  C CG2 . VAL B 2 85  ? 165.343 204.454 203.279 1.00 78.64  ? 101 VAL B CG2 1 
ATOM   3582  N N   . ILE B 2 86  ? 166.649 202.091 200.713 1.00 77.61  ? 102 ILE B N   1 
ATOM   3583  C CA  . ILE B 2 86  ? 167.208 202.470 199.422 1.00 77.51  ? 102 ILE B CA  1 
ATOM   3584  C C   . ILE B 2 86  ? 166.138 203.220 198.645 1.00 74.75  ? 102 ILE B C   1 
ATOM   3585  O O   . ILE B 2 86  ? 164.997 202.752 198.539 1.00 69.17  ? 102 ILE B O   1 
ATOM   3586  C CB  . ILE B 2 86  ? 167.702 201.244 198.634 1.00 76.95  ? 102 ILE B CB  1 
ATOM   3587  C CG1 . ILE B 2 86  ? 168.765 200.489 199.430 1.00 77.92  ? 102 ILE B CG1 1 
ATOM   3588  C CG2 . ILE B 2 86  ? 168.247 201.663 197.281 1.00 78.61  ? 102 ILE B CG2 1 
ATOM   3589  C CD1 . ILE B 2 86  ? 168.355 199.096 199.814 1.00 70.55  ? 102 ILE B CD1 1 
ATOM   3590  N N   . VAL B 2 87  ? 166.499 204.383 198.111 1.00 80.09  ? 103 VAL B N   1 
ATOM   3591  C CA  . VAL B 2 87  ? 165.590 205.215 197.333 1.00 75.39  ? 103 VAL B CA  1 
ATOM   3592  C C   . VAL B 2 87  ? 166.067 205.209 195.888 1.00 73.02  ? 103 VAL B C   1 
ATOM   3593  O O   . VAL B 2 87  ? 167.219 205.558 195.605 1.00 73.53  ? 103 VAL B O   1 
ATOM   3594  C CB  . VAL B 2 87  ? 165.515 206.646 197.885 1.00 72.95  ? 103 VAL B CB  1 
ATOM   3595  C CG1 . VAL B 2 87  ? 164.248 207.333 197.405 1.00 71.99  ? 103 VAL B CG1 1 
ATOM   3596  C CG2 . VAL B 2 87  ? 165.572 206.633 199.402 1.00 69.70  ? 103 VAL B CG2 1 
ATOM   3597  N N   . LEU B 2 88  ? 165.184 204.811 194.977 1.00 68.94  ? 104 LEU B N   1 
ATOM   3598  C CA  . LEU B 2 88  ? 165.461 204.813 193.548 1.00 71.85  ? 104 LEU B CA  1 
ATOM   3599  C C   . LEU B 2 88  ? 164.674 205.939 192.894 1.00 73.66  ? 104 LEU B C   1 
ATOM   3600  O O   . LEU B 2 88  ? 163.497 206.143 193.210 1.00 74.86  ? 104 LEU B O   1 
ATOM   3601  C CB  . LEU B 2 88  ? 165.105 203.467 192.914 1.00 68.22  ? 104 LEU B CB  1 
ATOM   3602  C CG  . LEU B 2 88  ? 165.480 202.214 193.710 1.00 63.48  ? 104 LEU B CG  1 
ATOM   3603  C CD1 . LEU B 2 88  ? 164.876 200.980 193.075 1.00 52.57  ? 104 LEU B CD1 1 
ATOM   3604  C CD2 . LEU B 2 88  ? 166.987 202.073 193.814 1.00 67.04  ? 104 LEU B CD2 1 
ATOM   3605  N N   . GLN B 2 89  ? 165.326 206.672 191.990 1.00 74.22  ? 105 GLN B N   1 
ATOM   3606  C CA  . GLN B 2 89  ? 164.740 207.867 191.404 1.00 79.66  ? 105 GLN B CA  1 
ATOM   3607  C C   . GLN B 2 89  ? 164.606 207.827 189.889 1.00 79.23  ? 105 GLN B C   1 
ATOM   3608  O O   . GLN B 2 89  ? 163.960 208.717 189.324 1.00 82.84  ? 105 GLN B O   1 
ATOM   3609  C CB  . GLN B 2 89  ? 165.562 209.107 191.794 1.00 83.42  ? 105 GLN B CB  1 
ATOM   3610  C CG  . GLN B 2 89  ? 166.976 209.109 191.240 1.00 84.88  ? 105 GLN B CG  1 
ATOM   3611  C CD  . GLN B 2 89  ? 167.971 208.488 192.197 1.00 85.22  ? 105 GLN B CD  1 
ATOM   3612  O OE1 . GLN B 2 89  ? 167.592 207.896 193.206 1.00 84.30  ? 105 GLN B OE1 1 
ATOM   3613  N NE2 . GLN B 2 89  ? 169.255 208.617 191.883 1.00 90.00  ? 105 GLN B NE2 1 
ATOM   3614  N N   . ASP B 2 90  ? 165.188 206.839 189.215 1.00 74.98  ? 106 ASP B N   1 
ATOM   3615  C CA  . ASP B 2 90  ? 165.104 206.740 187.765 1.00 75.24  ? 106 ASP B CA  1 
ATOM   3616  C C   . ASP B 2 90  ? 163.976 205.832 187.295 1.00 69.19  ? 106 ASP B C   1 
ATOM   3617  O O   . ASP B 2 90  ? 163.846 205.601 186.089 1.00 70.08  ? 106 ASP B O   1 
ATOM   3618  C CB  . ASP B 2 90  ? 166.436 206.247 187.192 1.00 78.24  ? 106 ASP B CB  1 
ATOM   3619  C CG  . ASP B 2 90  ? 167.217 207.348 186.505 1.00 83.68  ? 106 ASP B CG  1 
ATOM   3620  O OD1 . ASP B 2 90  ? 166.690 208.476 186.404 1.00 87.05  ? 106 ASP B OD1 1 
ATOM   3621  O OD2 . ASP B 2 90  ? 168.356 207.087 186.065 1.00 80.99  ? 106 ASP B OD2 1 
ATOM   3622  N N   . VAL B 2 91  ? 163.161 205.317 188.210 1.00 62.81  ? 107 VAL B N   1 
ATOM   3623  C CA  . VAL B 2 91  ? 162.091 204.382 187.888 1.00 56.67  ? 107 VAL B CA  1 
ATOM   3624  C C   . VAL B 2 91  ? 160.821 204.841 188.591 1.00 58.00  ? 107 VAL B C   1 
ATOM   3625  O O   . VAL B 2 91  ? 160.859 205.241 189.760 1.00 63.69  ? 107 VAL B O   1 
ATOM   3626  C CB  . VAL B 2 91  ? 162.468 202.940 188.297 1.00 54.15  ? 107 VAL B CB  1 
ATOM   3627  C CG1 . VAL B 2 91  ? 163.010 202.913 189.716 1.00 54.87  ? 107 VAL B CG1 1 
ATOM   3628  C CG2 . VAL B 2 91  ? 161.284 202.006 188.157 1.00 49.98  ? 107 VAL B CG2 1 
ATOM   3629  N N   . SER B 2 92  ? 159.701 204.805 187.874 1.00 53.82  ? 108 SER B N   1 
ATOM   3630  C CA  . SER B 2 92  ? 158.429 205.186 188.466 1.00 52.87  ? 108 SER B CA  1 
ATOM   3631  C C   . SER B 2 92  ? 157.828 204.014 189.239 1.00 54.98  ? 108 SER B C   1 
ATOM   3632  O O   . SER B 2 92  ? 158.328 202.887 189.207 1.00 54.49  ? 108 SER B O   1 
ATOM   3633  C CB  . SER B 2 92  ? 157.461 205.680 187.393 1.00 52.94  ? 108 SER B CB  1 
ATOM   3634  O OG  . SER B 2 92  ? 156.894 204.603 186.672 1.00 52.32  ? 108 SER B OG  1 
ATOM   3635  N N   . GLU B 2 93  ? 156.737 204.297 189.953 1.00 56.18  ? 109 GLU B N   1 
ATOM   3636  C CA  . GLU B 2 93  ? 156.144 203.294 190.832 1.00 52.43  ? 109 GLU B CA  1 
ATOM   3637  C C   . GLU B 2 93  ? 155.547 202.131 190.046 1.00 51.48  ? 109 GLU B C   1 
ATOM   3638  O O   . GLU B 2 93  ? 155.682 200.970 190.451 1.00 56.26  ? 109 GLU B O   1 
ATOM   3639  C CB  . GLU B 2 93  ? 155.085 203.945 191.720 1.00 52.21  ? 109 GLU B CB  1 
ATOM   3640  C CG  . GLU B 2 93  ? 154.612 203.070 192.865 1.00 57.84  ? 109 GLU B CG  1 
ATOM   3641  C CD  . GLU B 2 93  ? 153.198 202.565 192.666 1.00 63.75  ? 109 GLU B CD  1 
ATOM   3642  O OE1 . GLU B 2 93  ? 152.302 203.392 192.398 1.00 68.21  ? 109 GLU B OE1 1 
ATOM   3643  O OE2 . GLU B 2 93  ? 152.982 201.340 192.772 1.00 64.45  ? 109 GLU B OE2 1 
ATOM   3644  N N   . SER B 2 94  ? 154.888 202.418 188.922 1.00 47.79  ? 110 SER B N   1 
ATOM   3645  C CA  . SER B 2 94  ? 154.191 201.368 188.183 1.00 48.66  ? 110 SER B CA  1 
ATOM   3646  C C   . SER B 2 94  ? 155.168 200.381 187.557 1.00 45.58  ? 110 SER B C   1 
ATOM   3647  O O   . SER B 2 94  ? 154.993 199.160 187.668 1.00 48.80  ? 110 SER B O   1 
ATOM   3648  C CB  . SER B 2 94  ? 153.293 201.991 187.115 1.00 50.47  ? 110 SER B CB  1 
ATOM   3649  O OG  . SER B 2 94  ? 154.025 202.878 186.290 1.00 56.27  ? 110 SER B OG  1 
ATOM   3650  N N   . VAL B 2 95  ? 156.209 200.886 186.893 1.00 42.80  ? 111 VAL B N   1 
ATOM   3651  C CA  . VAL B 2 95  ? 157.166 199.977 186.272 1.00 41.03  ? 111 VAL B CA  1 
ATOM   3652  C C   . VAL B 2 95  ? 157.958 199.225 187.331 1.00 40.31  ? 111 VAL B C   1 
ATOM   3653  O O   . VAL B 2 95  ? 158.329 198.066 187.123 1.00 41.19  ? 111 VAL B O   1 
ATOM   3654  C CB  . VAL B 2 95  ? 158.088 200.726 185.294 1.00 41.84  ? 111 VAL B CB  1 
ATOM   3655  C CG1 . VAL B 2 95  ? 157.375 200.947 183.972 1.00 39.29  ? 111 VAL B CG1 1 
ATOM   3656  C CG2 . VAL B 2 95  ? 158.534 202.039 185.882 1.00 47.34  ? 111 VAL B CG2 1 
ATOM   3657  N N   . PHE B 2 96  ? 158.233 199.852 188.477 1.00 41.79  ? 112 PHE B N   1 
ATOM   3658  C CA  . PHE B 2 96  ? 158.913 199.126 189.545 1.00 39.91  ? 112 PHE B CA  1 
ATOM   3659  C C   . PHE B 2 96  ? 158.037 198.012 190.104 1.00 38.85  ? 112 PHE B C   1 
ATOM   3660  O O   . PHE B 2 96  ? 158.538 196.930 190.428 1.00 40.83  ? 112 PHE B O   1 
ATOM   3661  C CB  . PHE B 2 96  ? 159.345 200.072 190.661 1.00 41.82  ? 112 PHE B CB  1 
ATOM   3662  C CG  . PHE B 2 96  ? 160.323 199.453 191.617 1.00 44.98  ? 112 PHE B CG  1 
ATOM   3663  C CD1 . PHE B 2 96  ? 161.610 199.151 191.209 1.00 43.71  ? 112 PHE B CD1 1 
ATOM   3664  C CD2 . PHE B 2 96  ? 159.950 199.151 192.914 1.00 45.55  ? 112 PHE B CD2 1 
ATOM   3665  C CE1 . PHE B 2 96  ? 162.509 198.571 192.078 1.00 41.55  ? 112 PHE B CE1 1 
ATOM   3666  C CE2 . PHE B 2 96  ? 160.846 198.572 193.788 1.00 44.53  ? 112 PHE B CE2 1 
ATOM   3667  C CZ  . PHE B 2 96  ? 162.127 198.282 193.370 1.00 42.91  ? 112 PHE B CZ  1 
ATOM   3668  N N   . GLN B 2 97  ? 156.732 198.254 190.235 1.00 35.51  ? 113 GLN B N   1 
ATOM   3669  C CA  . GLN B 2 97  ? 155.830 197.180 190.638 1.00 37.01  ? 113 GLN B CA  1 
ATOM   3670  C C   . GLN B 2 97  ? 155.820 196.060 189.604 1.00 35.95  ? 113 GLN B C   1 
ATOM   3671  O O   . GLN B 2 97  ? 155.779 194.874 189.957 1.00 36.89  ? 113 GLN B O   1 
ATOM   3672  C CB  . GLN B 2 97  ? 154.422 197.731 190.857 1.00 41.25  ? 113 GLN B CB  1 
ATOM   3673  C CG  . GLN B 2 97  ? 153.377 196.672 191.169 1.00 44.84  ? 113 GLN B CG  1 
ATOM   3674  C CD  . GLN B 2 97  ? 153.676 195.913 192.446 1.00 50.53  ? 113 GLN B CD  1 
ATOM   3675  O OE1 . GLN B 2 97  ? 153.990 196.506 193.475 1.00 57.48  ? 113 GLN B OE1 1 
ATOM   3676  N NE2 . GLN B 2 97  ? 153.577 194.591 192.384 1.00 44.18  ? 113 GLN B NE2 1 
ATOM   3677  N N   . LEU B 2 98  ? 155.864 196.419 188.319 1.00 35.85  ? 114 LEU B N   1 
ATOM   3678  C CA  . LEU B 2 98  ? 155.951 195.410 187.266 1.00 32.29  ? 114 LEU B CA  1 
ATOM   3679  C C   . LEU B 2 98  ? 157.218 194.572 187.403 1.00 33.81  ? 114 LEU B C   1 
ATOM   3680  O O   . LEU B 2 98  ? 157.178 193.340 187.281 1.00 35.02  ? 114 LEU B O   1 
ATOM   3681  C CB  . LEU B 2 98  ? 155.910 196.085 185.895 1.00 33.44  ? 114 LEU B CB  1 
ATOM   3682  C CG  . LEU B 2 98  ? 154.548 196.320 185.249 1.00 36.80  ? 114 LEU B CG  1 
ATOM   3683  C CD1 . LEU B 2 98  ? 154.593 197.560 184.379 1.00 39.53  ? 114 LEU B CD1 1 
ATOM   3684  C CD2 . LEU B 2 98  ? 154.128 195.115 184.434 1.00 33.40  ? 114 LEU B CD2 1 
ATOM   3685  N N   . LEU B 2 99  ? 158.354 195.225 187.656 1.00 32.02  ? 115 LEU B N   1 
ATOM   3686  C CA  . LEU B 2 99  ? 159.612 194.500 187.810 1.00 28.92  ? 115 LEU B CA  1 
ATOM   3687  C C   . LEU B 2 99  ? 159.601 193.623 189.054 1.00 31.70  ? 115 LEU B C   1 
ATOM   3688  O O   . LEU B 2 99  ? 160.170 192.529 189.049 1.00 33.00  ? 115 LEU B O   1 
ATOM   3689  C CB  . LEU B 2 99  ? 160.788 195.470 187.864 1.00 33.08  ? 115 LEU B CB  1 
ATOM   3690  C CG  . LEU B 2 99  ? 160.970 196.457 186.716 1.00 35.62  ? 115 LEU B CG  1 
ATOM   3691  C CD1 . LEU B 2 99  ? 161.813 197.609 187.197 1.00 35.70  ? 115 LEU B CD1 1 
ATOM   3692  C CD2 . LEU B 2 99  ? 161.604 195.791 185.511 1.00 30.47  ? 115 LEU B CD2 1 
ATOM   3693  N N   . VAL B 2 100 ? 158.983 194.097 190.136 1.00 33.03  ? 116 VAL B N   1 
ATOM   3694  C CA  . VAL B 2 100 ? 158.873 193.285 191.345 1.00 30.91  ? 116 VAL B CA  1 
ATOM   3695  C C   . VAL B 2 100 ? 158.041 192.040 191.071 1.00 28.67  ? 116 VAL B C   1 
ATOM   3696  O O   . VAL B 2 100 ? 158.392 190.931 191.497 1.00 30.38  ? 116 VAL B O   1 
ATOM   3697  C CB  . VAL B 2 100 ? 158.287 194.126 192.495 1.00 33.10  ? 116 VAL B CB  1 
ATOM   3698  C CG1 . VAL B 2 100 ? 157.553 193.245 193.491 1.00 35.50  ? 116 VAL B CG1 1 
ATOM   3699  C CG2 . VAL B 2 100 ? 159.387 194.915 193.183 1.00 32.84  ? 116 VAL B CG2 1 
ATOM   3700  N N   . ASP B 2 101 ? 156.929 192.202 190.350 1.00 31.24  ? 117 ASP B N   1 
ATOM   3701  C CA  . ASP B 2 101 ? 156.112 191.051 189.982 1.00 30.17  ? 117 ASP B CA  1 
ATOM   3702  C C   . ASP B 2 101 ? 156.897 190.070 189.122 1.00 27.81  ? 117 ASP B C   1 
ATOM   3703  O O   . ASP B 2 101 ? 156.811 188.854 189.322 1.00 30.32  ? 117 ASP B O   1 
ATOM   3704  C CB  . ASP B 2 101 ? 154.852 191.513 189.253 1.00 33.44  ? 117 ASP B CB  1 
ATOM   3705  C CG  . ASP B 2 101 ? 153.901 192.271 190.156 1.00 41.27  ? 117 ASP B CG  1 
ATOM   3706  O OD1 . ASP B 2 101 ? 153.684 191.826 191.302 1.00 45.18  ? 117 ASP B OD1 1 
ATOM   3707  O OD2 . ASP B 2 101 ? 153.367 193.312 189.720 1.00 43.15  ? 117 ASP B OD2 1 
ATOM   3708  N N   . TYR B 2 102 ? 157.668 190.578 188.159 1.00 27.19  ? 118 TYR B N   1 
ATOM   3709  C CA  . TYR B 2 102 ? 158.475 189.694 187.322 1.00 24.09  ? 118 TYR B CA  1 
ATOM   3710  C C   . TYR B 2 102 ? 159.538 188.966 188.138 1.00 23.97  ? 118 TYR B C   1 
ATOM   3711  O O   . TYR B 2 102 ? 159.771 187.769 187.939 1.00 25.79  ? 118 TYR B O   1 
ATOM   3712  C CB  . TYR B 2 102 ? 159.128 190.485 186.189 1.00 21.82  ? 118 TYR B CB  1 
ATOM   3713  C CG  . TYR B 2 102 ? 160.197 189.711 185.454 1.00 17.98  ? 118 TYR B CG  1 
ATOM   3714  C CD1 . TYR B 2 102 ? 159.863 188.712 184.553 1.00 17.96  ? 118 TYR B CD1 1 
ATOM   3715  C CD2 . TYR B 2 102 ? 161.542 189.975 185.666 1.00 18.15  ? 118 TYR B CD2 1 
ATOM   3716  C CE1 . TYR B 2 102 ? 160.836 188.001 183.884 1.00 16.26  ? 118 TYR B CE1 1 
ATOM   3717  C CE2 . TYR B 2 102 ? 162.520 189.267 185.003 1.00 17.58  ? 118 TYR B CE2 1 
ATOM   3718  C CZ  . TYR B 2 102 ? 162.162 188.283 184.114 1.00 17.00  ? 118 TYR B CZ  1 
ATOM   3719  O OH  . TYR B 2 102 ? 163.139 187.581 183.451 1.00 23.58  ? 118 TYR B OH  1 
ATOM   3720  N N   . ILE B 2 103 ? 160.201 189.674 189.051 1.00 24.85  ? 119 ILE B N   1 
ATOM   3721  C CA  . ILE B 2 103 ? 161.270 189.072 189.839 1.00 23.72  ? 119 ILE B CA  1 
ATOM   3722  C C   . ILE B 2 103 ? 160.720 187.980 190.745 1.00 26.64  ? 119 ILE B C   1 
ATOM   3723  O O   . ILE B 2 103 ? 161.301 186.894 190.855 1.00 28.05  ? 119 ILE B O   1 
ATOM   3724  C CB  . ILE B 2 103 ? 162.010 190.157 190.643 1.00 24.06  ? 119 ILE B CB  1 
ATOM   3725  C CG1 . ILE B 2 103 ? 163.110 190.795 189.797 1.00 25.43  ? 119 ILE B CG1 1 
ATOM   3726  C CG2 . ILE B 2 103 ? 162.595 189.584 191.921 1.00 25.04  ? 119 ILE B CG2 1 
ATOM   3727  C CD1 . ILE B 2 103 ? 163.884 191.867 190.521 1.00 25.26  ? 119 ILE B CD1 1 
ATOM   3728  N N   . TYR B 2 104 ? 159.587 188.239 191.400 1.00 28.83  ? 120 TYR B N   1 
ATOM   3729  C CA  . TYR B 2 104 ? 159.099 187.294 192.397 1.00 25.52  ? 120 TYR B CA  1 
ATOM   3730  C C   . TYR B 2 104 ? 158.310 186.151 191.772 1.00 28.09  ? 120 TYR B C   1 
ATOM   3731  O O   . TYR B 2 104 ? 158.405 185.010 192.236 1.00 31.40  ? 120 TYR B O   1 
ATOM   3732  C CB  . TYR B 2 104 ? 158.259 188.026 193.439 1.00 26.27  ? 120 TYR B CB  1 
ATOM   3733  C CG  . TYR B 2 104 ? 159.095 188.669 194.518 1.00 29.85  ? 120 TYR B CG  1 
ATOM   3734  C CD1 . TYR B 2 104 ? 159.700 189.899 194.312 1.00 29.76  ? 120 TYR B CD1 1 
ATOM   3735  C CD2 . TYR B 2 104 ? 159.295 188.038 195.735 1.00 33.01  ? 120 TYR B CD2 1 
ATOM   3736  C CE1 . TYR B 2 104 ? 160.470 190.487 195.291 1.00 31.71  ? 120 TYR B CE1 1 
ATOM   3737  C CE2 . TYR B 2 104 ? 160.064 188.620 196.719 1.00 31.76  ? 120 TYR B CE2 1 
ATOM   3738  C CZ  . TYR B 2 104 ? 160.648 189.843 196.492 1.00 31.08  ? 120 TYR B CZ  1 
ATOM   3739  O OH  . TYR B 2 104 ? 161.414 190.427 197.471 1.00 34.16  ? 120 TYR B OH  1 
ATOM   3740  N N   . HIS B 2 105 ? 157.533 186.422 190.721 1.00 29.36  ? 121 HIS B N   1 
ATOM   3741  C CA  . HIS B 2 105 ? 156.660 185.416 190.137 1.00 27.88  ? 121 HIS B CA  1 
ATOM   3742  C C   . HIS B 2 105 ? 157.141 184.873 188.802 1.00 27.12  ? 121 HIS B C   1 
ATOM   3743  O O   . HIS B 2 105 ? 156.729 183.774 188.422 1.00 31.44  ? 121 HIS B O   1 
ATOM   3744  C CB  . HIS B 2 105 ? 155.246 185.984 189.956 1.00 30.66  ? 121 HIS B CB  1 
ATOM   3745  C CG  . HIS B 2 105 ? 154.668 186.568 191.206 1.00 37.06  ? 121 HIS B CG  1 
ATOM   3746  N ND1 . HIS B 2 105 ? 154.307 187.893 191.310 1.00 41.71  ? 121 HIS B ND1 1 
ATOM   3747  C CD2 . HIS B 2 105 ? 154.395 186.008 192.408 1.00 41.03  ? 121 HIS B CD2 1 
ATOM   3748  C CE1 . HIS B 2 105 ? 153.835 188.125 192.522 1.00 45.10  ? 121 HIS B CE1 1 
ATOM   3749  N NE2 . HIS B 2 105 ? 153.877 186.998 193.208 1.00 47.63  ? 121 HIS B NE2 1 
ATOM   3750  N N   . GLY B 2 106 ? 157.991 185.601 188.086 1.00 26.70  ? 122 GLY B N   1 
ATOM   3751  C CA  . GLY B 2 106 ? 158.479 185.151 186.801 1.00 24.94  ? 122 GLY B CA  1 
ATOM   3752  C C   . GLY B 2 106 ? 157.556 185.422 185.638 1.00 28.49  ? 122 GLY B C   1 
ATOM   3753  O O   . GLY B 2 106 ? 157.920 185.112 184.497 1.00 31.09  ? 122 GLY B O   1 
ATOM   3754  N N   . THR B 2 107 ? 156.379 185.989 185.885 1.00 29.60  ? 123 THR B N   1 
ATOM   3755  C CA  . THR B 2 107 ? 155.398 186.288 184.853 1.00 24.15  ? 123 THR B CA  1 
ATOM   3756  C C   . THR B 2 107 ? 155.072 187.772 184.902 1.00 23.20  ? 123 THR B C   1 
ATOM   3757  O O   . THR B 2 107 ? 154.768 188.308 185.972 1.00 25.11  ? 123 THR B O   1 
ATOM   3758  C CB  . THR B 2 107 ? 154.125 185.461 185.045 1.00 27.75  ? 123 THR B CB  1 
ATOM   3759  O OG1 . THR B 2 107 ? 154.473 184.124 185.420 1.00 31.77  ? 123 THR B OG1 1 
ATOM   3760  C CG2 . THR B 2 107 ? 153.322 185.417 183.764 1.00 30.97  ? 123 THR B CG2 1 
ATOM   3761  N N   . VAL B 2 108 ? 155.129 188.429 183.745 1.00 26.24  ? 124 VAL B N   1 
ATOM   3762  C CA  . VAL B 2 108 ? 154.903 189.864 183.643 1.00 23.73  ? 124 VAL B CA  1 
ATOM   3763  C C   . VAL B 2 108 ? 154.015 190.139 182.436 1.00 22.84  ? 124 VAL B C   1 
ATOM   3764  O O   . VAL B 2 108 ? 154.094 189.454 181.413 1.00 25.73  ? 124 VAL B O   1 
ATOM   3765  C CB  . VAL B 2 108 ? 156.240 190.640 183.555 1.00 21.69  ? 124 VAL B CB  1 
ATOM   3766  C CG1 . VAL B 2 108 ? 156.986 190.294 182.280 1.00 19.90  ? 124 VAL B CG1 1 
ATOM   3767  C CG2 . VAL B 2 108 ? 156.013 192.134 183.662 1.00 22.37  ? 124 VAL B CG2 1 
ATOM   3768  N N   . LYS B 2 109 ? 153.145 191.136 182.571 1.00 21.90  ? 125 LYS B N   1 
ATOM   3769  C CA  . LYS B 2 109 ? 152.255 191.557 181.497 1.00 21.12  ? 125 LYS B CA  1 
ATOM   3770  C C   . LYS B 2 109 ? 152.854 192.779 180.813 1.00 23.22  ? 125 LYS B C   1 
ATOM   3771  O O   . LYS B 2 109 ? 153.011 193.831 181.440 1.00 27.91  ? 125 LYS B O   1 
ATOM   3772  C CB  . LYS B 2 109 ? 150.861 191.871 182.034 1.00 24.47  ? 125 LYS B CB  1 
ATOM   3773  C CG  . LYS B 2 109 ? 149.847 192.212 180.958 1.00 28.31  ? 125 LYS B CG  1 
ATOM   3774  C CD  . LYS B 2 109 ? 148.825 191.099 180.794 1.00 32.57  ? 125 LYS B CD  1 
ATOM   3775  C CE  . LYS B 2 109 ? 147.875 191.386 179.644 1.00 34.51  ? 125 LYS B CE  1 
ATOM   3776  N NZ  . LYS B 2 109 ? 147.155 190.162 179.199 1.00 33.67  ? 125 LYS B NZ  1 
ATOM   3777  N N   . LEU B 2 110 ? 153.173 192.641 179.530 1.00 21.21  ? 126 LEU B N   1 
ATOM   3778  C CA  . LEU B 2 110 ? 153.866 193.675 178.776 1.00 21.61  ? 126 LEU B CA  1 
ATOM   3779  C C   . LEU B 2 110 ? 152.880 194.440 177.904 1.00 23.88  ? 126 LEU B C   1 
ATOM   3780  O O   . LEU B 2 110 ? 152.154 193.839 177.108 1.00 23.94  ? 126 LEU B O   1 
ATOM   3781  C CB  . LEU B 2 110 ? 154.968 193.064 177.910 1.00 23.08  ? 126 LEU B CB  1 
ATOM   3782  C CG  . LEU B 2 110 ? 156.082 192.304 178.629 1.00 19.54  ? 126 LEU B CG  1 
ATOM   3783  C CD1 . LEU B 2 110 ? 157.045 191.703 177.625 1.00 18.47  ? 126 LEU B CD1 1 
ATOM   3784  C CD2 . LEU B 2 110 ? 156.814 193.214 179.594 1.00 18.11  ? 126 LEU B CD2 1 
ATOM   3785  N N   . ARG B 2 111 ? 152.865 195.762 178.053 1.00 25.78  ? 127 ARG B N   1 
ATOM   3786  C CA  . ARG B 2 111 ? 152.044 196.643 177.238 1.00 25.84  ? 127 ARG B CA  1 
ATOM   3787  C C   . ARG B 2 111 ? 152.935 197.578 176.435 1.00 26.26  ? 127 ARG B C   1 
ATOM   3788  O O   . ARG B 2 111 ? 154.019 197.961 176.881 1.00 30.55  ? 127 ARG B O   1 
ATOM   3789  C CB  . ARG B 2 111 ? 151.079 197.469 178.092 1.00 30.50  ? 127 ARG B CB  1 
ATOM   3790  C CG  . ARG B 2 111 ? 150.272 196.664 179.086 1.00 35.92  ? 127 ARG B CG  1 
ATOM   3791  C CD  . ARG B 2 111 ? 149.072 197.452 179.574 1.00 41.99  ? 127 ARG B CD  1 
ATOM   3792  N NE  . ARG B 2 111 ? 149.459 198.551 180.450 1.00 49.22  ? 127 ARG B NE  1 
ATOM   3793  C CZ  . ARG B 2 111 ? 149.474 199.827 180.090 1.00 49.69  ? 127 ARG B CZ  1 
ATOM   3794  N NH1 . ARG B 2 111 ? 149.131 200.205 178.871 1.00 47.61  ? 127 ARG B NH1 1 
ATOM   3795  N NH2 . ARG B 2 111 ? 149.842 200.747 180.977 1.00 47.66  ? 127 ARG B NH2 1 
ATOM   3796  N N   . ALA B 2 112 ? 152.465 197.946 175.243 1.00 24.18  ? 128 ALA B N   1 
ATOM   3797  C CA  . ALA B 2 112 ? 153.227 198.833 174.376 1.00 23.83  ? 128 ALA B CA  1 
ATOM   3798  C C   . ALA B 2 112 ? 153.232 200.275 174.861 1.00 29.19  ? 128 ALA B C   1 
ATOM   3799  O O   . ALA B 2 112 ? 154.056 201.065 174.389 1.00 28.06  ? 128 ALA B O   1 
ATOM   3800  C CB  . ALA B 2 112 ? 152.680 198.769 172.951 1.00 22.82  ? 128 ALA B CB  1 
ATOM   3801  N N   . GLU B 2 113 ? 152.342 200.636 175.784 1.00 31.53  ? 129 GLU B N   1 
ATOM   3802  C CA  . GLU B 2 113 ? 152.276 201.996 176.299 1.00 31.08  ? 129 GLU B CA  1 
ATOM   3803  C C   . GLU B 2 113 ? 153.380 202.307 177.300 1.00 32.75  ? 129 GLU B C   1 
ATOM   3804  O O   . GLU B 2 113 ? 153.612 203.484 177.596 1.00 32.38  ? 129 GLU B O   1 
ATOM   3805  C CB  . GLU B 2 113 ? 150.911 202.243 176.946 1.00 35.06  ? 129 GLU B CB  1 
ATOM   3806  C CG  . GLU B 2 113 ? 149.743 202.237 175.968 1.00 41.86  ? 129 GLU B CG  1 
ATOM   3807  C CD  . GLU B 2 113 ? 149.220 200.841 175.673 1.00 43.54  ? 129 GLU B CD  1 
ATOM   3808  O OE1 . GLU B 2 113 ? 149.347 200.387 174.517 1.00 41.56  ? 129 GLU B OE1 1 
ATOM   3809  O OE2 . GLU B 2 113 ? 148.680 200.199 176.596 1.00 44.33  ? 129 GLU B OE2 1 
ATOM   3810  N N   . GLU B 2 114 ? 154.062 201.288 177.826 1.00 31.10  ? 130 GLU B N   1 
ATOM   3811  C CA  . GLU B 2 114 ? 155.157 201.479 178.768 1.00 28.07  ? 130 GLU B CA  1 
ATOM   3812  C C   . GLU B 2 114 ? 156.361 200.626 178.390 1.00 27.03  ? 130 GLU B C   1 
ATOM   3813  O O   . GLU B 2 114 ? 157.137 200.221 179.260 1.00 33.26  ? 130 GLU B O   1 
ATOM   3814  C CB  . GLU B 2 114 ? 154.710 201.157 180.193 1.00 31.28  ? 130 GLU B CB  1 
ATOM   3815  C CG  . GLU B 2 114 ? 154.195 199.741 180.371 1.00 37.05  ? 130 GLU B CG  1 
ATOM   3816  C CD  . GLU B 2 114 ? 153.346 199.578 181.613 1.00 48.32  ? 130 GLU B CD  1 
ATOM   3817  O OE1 . GLU B 2 114 ? 153.529 200.362 182.568 1.00 52.12  ? 130 GLU B OE1 1 
ATOM   3818  O OE2 . GLU B 2 114 ? 152.499 198.661 181.637 1.00 46.28  ? 130 GLU B OE2 1 
ATOM   3819  N N   . LEU B 2 115 ? 156.536 200.355 177.097 1.00 25.56  ? 131 LEU B N   1 
ATOM   3820  C CA  . LEU B 2 115 ? 157.546 199.397 176.660 1.00 22.81  ? 131 LEU B CA  1 
ATOM   3821  C C   . LEU B 2 115 ? 158.957 199.959 176.783 1.00 25.42  ? 131 LEU B C   1 
ATOM   3822  O O   . LEU B 2 115 ? 159.870 199.262 177.240 1.00 25.43  ? 131 LEU B O   1 
ATOM   3823  C CB  . LEU B 2 115 ? 157.258 198.978 175.221 1.00 23.68  ? 131 LEU B CB  1 
ATOM   3824  C CG  . LEU B 2 115 ? 158.063 197.821 174.644 1.00 21.47  ? 131 LEU B CG  1 
ATOM   3825  C CD1 . LEU B 2 115 ? 157.995 196.625 175.569 1.00 21.33  ? 131 LEU B CD1 1 
ATOM   3826  C CD2 . LEU B 2 115 ? 157.538 197.477 173.267 1.00 17.19  ? 131 LEU B CD2 1 
ATOM   3827  N N   . GLN B 2 116 ? 159.159 201.213 176.372 1.00 29.20  ? 132 GLN B N   1 
ATOM   3828  C CA  . GLN B 2 116 ? 160.500 201.788 176.375 1.00 24.92  ? 132 GLN B CA  1 
ATOM   3829  C C   . GLN B 2 116 ? 161.029 201.968 177.791 1.00 28.15  ? 132 GLN B C   1 
ATOM   3830  O O   . GLN B 2 116 ? 162.220 201.753 178.045 1.00 31.98  ? 132 GLN B O   1 
ATOM   3831  C CB  . GLN B 2 116 ? 160.499 203.120 175.628 1.00 26.45  ? 132 GLN B CB  1 
ATOM   3832  C CG  . GLN B 2 116 ? 159.619 203.132 174.393 1.00 29.90  ? 132 GLN B CG  1 
ATOM   3833  C CD  . GLN B 2 116 ? 160.305 203.749 173.194 1.00 33.57  ? 132 GLN B CD  1 
ATOM   3834  O OE1 . GLN B 2 116 ? 161.234 204.541 173.336 1.00 34.37  ? 132 GLN B OE1 1 
ATOM   3835  N NE2 . GLN B 2 116 ? 159.849 203.387 172.002 1.00 33.65  ? 132 GLN B NE2 1 
ATOM   3836  N N   . GLU B 2 117 ? 160.166 202.376 178.724 1.00 27.74  ? 133 GLU B N   1 
ATOM   3837  C CA  . GLU B 2 117 ? 160.602 202.541 180.107 1.00 27.40  ? 133 GLU B CA  1 
ATOM   3838  C C   . GLU B 2 117 ? 161.011 201.208 180.722 1.00 27.34  ? 133 GLU B C   1 
ATOM   3839  O O   . GLU B 2 117 ? 162.041 201.123 181.399 1.00 32.44  ? 133 GLU B O   1 
ATOM   3840  C CB  . GLU B 2 117 ? 159.497 203.197 180.931 1.00 32.01  ? 133 GLU B CB  1 
ATOM   3841  C CG  . GLU B 2 117 ? 159.753 203.171 182.427 1.00 43.26  ? 133 GLU B CG  1 
ATOM   3842  C CD  . GLU B 2 117 ? 159.575 204.525 183.079 1.00 47.33  ? 133 GLU B CD  1 
ATOM   3843  O OE1 . GLU B 2 117 ? 160.391 204.872 183.960 1.00 45.72  ? 133 GLU B OE1 1 
ATOM   3844  O OE2 . GLU B 2 117 ? 158.621 205.242 182.712 1.00 47.30  ? 133 GLU B OE2 1 
ATOM   3845  N N   . ILE B 2 118 ? 160.220 200.157 180.494 1.00 23.20  ? 134 ILE B N   1 
ATOM   3846  C CA  . ILE B 2 118 ? 160.587 198.832 180.986 1.00 21.38  ? 134 ILE B CA  1 
ATOM   3847  C C   . ILE B 2 118 ? 161.894 198.378 180.354 1.00 23.34  ? 134 ILE B C   1 
ATOM   3848  O O   . ILE B 2 118 ? 162.750 197.790 181.021 1.00 26.81  ? 134 ILE B O   1 
ATOM   3849  C CB  . ILE B 2 118 ? 159.454 197.824 180.723 1.00 21.75  ? 134 ILE B CB  1 
ATOM   3850  C CG1 . ILE B 2 118 ? 158.178 198.245 181.447 1.00 26.91  ? 134 ILE B CG1 1 
ATOM   3851  C CG2 . ILE B 2 118 ? 159.858 196.440 181.183 1.00 20.27  ? 134 ILE B CG2 1 
ATOM   3852  C CD1 . ILE B 2 118 ? 156.981 197.395 181.097 1.00 29.40  ? 134 ILE B CD1 1 
ATOM   3853  N N   . TYR B 2 119 ? 162.067 198.644 179.059 1.00 23.95  ? 135 TYR B N   1 
ATOM   3854  C CA  . TYR B 2 119 ? 163.302 198.293 178.364 1.00 22.37  ? 135 TYR B CA  1 
ATOM   3855  C C   . TYR B 2 119 ? 164.513 198.953 179.020 1.00 24.76  ? 135 TYR B C   1 
ATOM   3856  O O   . TYR B 2 119 ? 165.501 198.283 179.356 1.00 26.75  ? 135 TYR B O   1 
ATOM   3857  C CB  . TYR B 2 119 ? 163.165 198.706 176.896 1.00 21.48  ? 135 TYR B CB  1 
ATOM   3858  C CG  . TYR B 2 119 ? 164.378 198.529 176.015 1.00 22.75  ? 135 TYR B CG  1 
ATOM   3859  C CD1 . TYR B 2 119 ? 164.651 197.311 175.414 1.00 22.18  ? 135 TYR B CD1 1 
ATOM   3860  C CD2 . TYR B 2 119 ? 165.223 199.596 175.744 1.00 23.96  ? 135 TYR B CD2 1 
ATOM   3861  C CE1 . TYR B 2 119 ? 165.746 197.154 174.593 1.00 22.58  ? 135 TYR B CE1 1 
ATOM   3862  C CE2 . TYR B 2 119 ? 166.320 199.447 174.926 1.00 22.71  ? 135 TYR B CE2 1 
ATOM   3863  C CZ  . TYR B 2 119 ? 166.576 198.225 174.353 1.00 22.03  ? 135 TYR B CZ  1 
ATOM   3864  O OH  . TYR B 2 119 ? 167.669 198.071 173.536 1.00 26.25  ? 135 TYR B OH  1 
ATOM   3865  N N   . GLU B 2 120 ? 164.438 200.267 179.237 1.00 24.20  ? 136 GLU B N   1 
ATOM   3866  C CA  . GLU B 2 120 ? 165.561 200.991 179.825 1.00 24.69  ? 136 GLU B CA  1 
ATOM   3867  C C   . GLU B 2 120 ? 165.842 200.535 181.252 1.00 26.65  ? 136 GLU B C   1 
ATOM   3868  O O   . GLU B 2 120 ? 167.004 200.347 181.634 1.00 31.64  ? 136 GLU B O   1 
ATOM   3869  C CB  . GLU B 2 120 ? 165.293 202.494 179.791 1.00 26.97  ? 136 GLU B CB  1 
ATOM   3870  C CG  . GLU B 2 120 ? 165.079 203.061 178.404 1.00 31.66  ? 136 GLU B CG  1 
ATOM   3871  C CD  . GLU B 2 120 ? 164.450 204.438 178.436 1.00 45.48  ? 136 GLU B CD  1 
ATOM   3872  O OE1 . GLU B 2 120 ? 164.065 204.890 179.535 1.00 45.83  ? 136 GLU B OE1 1 
ATOM   3873  O OE2 . GLU B 2 120 ? 164.335 205.068 177.364 1.00 47.91  ? 136 GLU B OE2 1 
ATOM   3874  N N   . VAL B 2 121 ? 164.796 200.356 182.062 1.00 26.51  ? 137 VAL B N   1 
ATOM   3875  C CA  . VAL B 2 121 ? 165.024 199.977 183.453 1.00 25.66  ? 137 VAL B CA  1 
ATOM   3876  C C   . VAL B 2 121 ? 165.531 198.541 183.554 1.00 26.12  ? 137 VAL B C   1 
ATOM   3877  O O   . VAL B 2 121 ? 166.339 198.227 184.434 1.00 29.17  ? 137 VAL B O   1 
ATOM   3878  C CB  . VAL B 2 121 ? 163.751 200.199 184.289 1.00 28.82  ? 137 VAL B CB  1 
ATOM   3879  C CG1 . VAL B 2 121 ? 164.018 199.875 185.736 1.00 33.78  ? 137 VAL B CG1 1 
ATOM   3880  C CG2 . VAL B 2 121 ? 163.299 201.638 184.175 1.00 34.42  ? 137 VAL B CG2 1 
ATOM   3881  N N   . SER B 2 122 ? 165.075 197.648 182.673 1.00 26.00  ? 138 SER B N   1 
ATOM   3882  C CA  . SER B 2 122 ? 165.625 196.298 182.633 1.00 22.80  ? 138 SER B CA  1 
ATOM   3883  C C   . SER B 2 122 ? 167.097 196.317 182.248 1.00 25.47  ? 138 SER B C   1 
ATOM   3884  O O   . SER B 2 122 ? 167.894 195.534 182.775 1.00 25.24  ? 138 SER B O   1 
ATOM   3885  C CB  . SER B 2 122 ? 164.830 195.438 181.654 1.00 20.51  ? 138 SER B CB  1 
ATOM   3886  O OG  . SER B 2 122 ? 163.613 195.011 182.230 1.00 24.37  ? 138 SER B OG  1 
ATOM   3887  N N   . ASP B 2 123 ? 167.475 197.192 181.312 1.00 30.75  ? 139 ASP B N   1 
ATOM   3888  C CA  . ASP B 2 123 ? 168.891 197.337 180.989 1.00 27.98  ? 139 ASP B CA  1 
ATOM   3889  C C   . ASP B 2 123 ? 169.678 197.843 182.190 1.00 29.74  ? 139 ASP B C   1 
ATOM   3890  O O   . ASP B 2 123 ? 170.808 197.404 182.433 1.00 31.93  ? 139 ASP B O   1 
ATOM   3891  C CB  . ASP B 2 123 ? 169.070 198.280 179.801 1.00 31.42  ? 139 ASP B CB  1 
ATOM   3892  C CG  . ASP B 2 123 ? 170.521 198.418 179.380 1.00 42.73  ? 139 ASP B CG  1 
ATOM   3893  O OD1 . ASP B 2 123 ? 171.109 197.416 178.922 1.00 42.92  ? 139 ASP B OD1 1 
ATOM   3894  O OD2 . ASP B 2 123 ? 171.075 199.531 179.505 1.00 43.40  ? 139 ASP B OD2 1 
ATOM   3895  N N   . MET B 2 124 ? 169.099 198.775 182.949 1.00 33.03  ? 140 MET B N   1 
ATOM   3896  C CA  . MET B 2 124 ? 169.810 199.347 184.089 1.00 34.49  ? 140 MET B CA  1 
ATOM   3897  C C   . MET B 2 124 ? 169.972 198.335 185.219 1.00 31.90  ? 140 MET B C   1 
ATOM   3898  O O   . MET B 2 124 ? 171.046 198.242 185.824 1.00 34.87  ? 140 MET B O   1 
ATOM   3899  C CB  . MET B 2 124 ? 169.082 200.595 184.585 1.00 35.21  ? 140 MET B CB  1 
ATOM   3900  C CG  . MET B 2 124 ? 169.448 201.008 185.996 1.00 38.84  ? 140 MET B CG  1 
ATOM   3901  S SD  . MET B 2 124 ? 169.186 202.767 186.284 1.00 76.32  ? 140 MET B SD  1 
ATOM   3902  C CE  . MET B 2 124 ? 167.412 202.807 186.517 1.00 57.53  ? 140 MET B CE  1 
ATOM   3903  N N   . TYR B 2 125 ? 168.926 197.569 185.516 1.00 30.75  ? 141 TYR B N   1 
ATOM   3904  C CA  . TYR B 2 125 ? 168.942 196.610 186.615 1.00 27.72  ? 141 TYR B CA  1 
ATOM   3905  C C   . TYR B 2 125 ? 169.468 195.242 186.208 1.00 28.63  ? 141 TYR B C   1 
ATOM   3906  O O   . TYR B 2 125 ? 169.547 194.353 187.059 1.00 34.71  ? 141 TYR B O   1 
ATOM   3907  C CB  . TYR B 2 125 ? 167.538 196.458 187.211 1.00 26.85  ? 141 TYR B CB  1 
ATOM   3908  C CG  . TYR B 2 125 ? 167.032 197.692 187.920 1.00 31.30  ? 141 TYR B CG  1 
ATOM   3909  C CD1 . TYR B 2 125 ? 167.875 198.758 188.185 1.00 36.24  ? 141 TYR B CD1 1 
ATOM   3910  C CD2 . TYR B 2 125 ? 165.712 197.789 188.327 1.00 30.77  ? 141 TYR B CD2 1 
ATOM   3911  C CE1 . TYR B 2 125 ? 167.422 199.885 188.829 1.00 34.46  ? 141 TYR B CE1 1 
ATOM   3912  C CE2 . TYR B 2 125 ? 165.250 198.914 188.974 1.00 36.36  ? 141 TYR B CE2 1 
ATOM   3913  C CZ  . TYR B 2 125 ? 166.110 199.959 189.221 1.00 38.70  ? 141 TYR B CZ  1 
ATOM   3914  O OH  . TYR B 2 125 ? 165.661 201.086 189.865 1.00 49.87  ? 141 TYR B OH  1 
ATOM   3915  N N   . GLN B 2 126 ? 169.812 195.053 184.934 1.00 26.47  ? 142 GLN B N   1 
ATOM   3916  C CA  . GLN B 2 126 ? 170.431 193.820 184.445 1.00 23.56  ? 142 GLN B CA  1 
ATOM   3917  C C   . GLN B 2 126 ? 169.502 192.617 184.608 1.00 22.26  ? 142 GLN B C   1 
ATOM   3918  O O   . GLN B 2 126 ? 169.890 191.566 185.121 1.00 27.06  ? 142 GLN B O   1 
ATOM   3919  C CB  . GLN B 2 126 ? 171.779 193.575 185.126 1.00 29.97  ? 142 GLN B CB  1 
ATOM   3920  C CG  . GLN B 2 126 ? 172.911 194.421 184.573 1.00 31.53  ? 142 GLN B CG  1 
ATOM   3921  C CD  . GLN B 2 126 ? 173.919 194.810 185.632 1.00 35.91  ? 142 GLN B CD  1 
ATOM   3922  O OE1 . GLN B 2 126 ? 174.774 194.013 186.011 1.00 41.25  ? 142 GLN B OE1 1 
ATOM   3923  N NE2 . GLN B 2 126 ? 173.824 196.041 186.116 1.00 34.11  ? 142 GLN B NE2 1 
ATOM   3924  N N   . LEU B 2 127 ? 168.261 192.780 184.159 1.00 22.34  ? 143 LEU B N   1 
ATOM   3925  C CA  . LEU B 2 127 ? 167.301 191.682 184.049 1.00 21.92  ? 143 LEU B CA  1 
ATOM   3926  C C   . LEU B 2 127 ? 167.322 191.245 182.589 1.00 22.19  ? 143 LEU B C   1 
ATOM   3927  O O   . LEU B 2 127 ? 166.524 191.702 181.773 1.00 26.55  ? 143 LEU B O   1 
ATOM   3928  C CB  . LEU B 2 127 ? 165.912 192.117 184.501 1.00 19.63  ? 143 LEU B CB  1 
ATOM   3929  C CG  . LEU B 2 127 ? 165.820 192.791 185.872 1.00 19.73  ? 143 LEU B CG  1 
ATOM   3930  C CD1 . LEU B 2 127 ? 164.465 193.441 186.061 1.00 19.80  ? 143 LEU B CD1 1 
ATOM   3931  C CD2 . LEU B 2 127 ? 166.088 191.794 186.980 1.00 21.41  ? 143 LEU B CD2 1 
ATOM   3932  N N   . THR B 2 128 ? 168.252 190.343 182.264 1.00 21.02  ? 144 THR B N   1 
ATOM   3933  C CA  . THR B 2 128 ? 168.604 190.099 180.868 1.00 22.07  ? 144 THR B CA  1 
ATOM   3934  C C   . THR B 2 128 ? 167.455 189.478 180.080 1.00 25.46  ? 144 THR B C   1 
ATOM   3935  O O   . THR B 2 128 ? 167.239 189.834 178.917 1.00 31.19  ? 144 THR B O   1 
ATOM   3936  C CB  . THR B 2 128 ? 169.851 189.218 180.787 1.00 26.01  ? 144 THR B CB  1 
ATOM   3937  O OG1 . THR B 2 128 ? 170.013 188.739 179.447 1.00 31.49  ? 144 THR B OG1 1 
ATOM   3938  C CG2 . THR B 2 128 ? 169.743 188.038 181.740 1.00 32.88  ? 144 THR B CG2 1 
ATOM   3939  N N   . SER B 2 129 ? 166.714 188.544 180.680 1.00 24.44  ? 145 SER B N   1 
ATOM   3940  C CA  . SER B 2 129 ? 165.612 187.910 179.959 1.00 23.47  ? 145 SER B CA  1 
ATOM   3941  C C   . SER B 2 129 ? 164.493 188.902 179.668 1.00 24.39  ? 145 SER B C   1 
ATOM   3942  O O   . SER B 2 129 ? 163.948 188.932 178.555 1.00 27.93  ? 145 SER B O   1 
ATOM   3943  C CB  . SER B 2 129 ? 165.084 186.721 180.757 1.00 26.56  ? 145 SER B CB  1 
ATOM   3944  O OG  . SER B 2 129 ? 165.934 185.599 180.612 1.00 36.55  ? 145 SER B OG  1 
ATOM   3945  N N   . LEU B 2 130 ? 164.140 189.725 180.657 1.00 21.93  ? 146 LEU B N   1 
ATOM   3946  C CA  . LEU B 2 130 ? 163.151 190.771 180.431 1.00 18.45  ? 146 LEU B CA  1 
ATOM   3947  C C   . LEU B 2 130 ? 163.647 191.775 179.400 1.00 22.93  ? 146 LEU B C   1 
ATOM   3948  O O   . LEU B 2 130 ? 162.867 192.266 178.577 1.00 26.84  ? 146 LEU B O   1 
ATOM   3949  C CB  . LEU B 2 130 ? 162.817 191.469 181.748 1.00 15.83  ? 146 LEU B CB  1 
ATOM   3950  C CG  . LEU B 2 130 ? 161.556 192.329 181.758 1.00 15.28  ? 146 LEU B CG  1 
ATOM   3951  C CD1 . LEU B 2 130 ? 160.371 191.529 181.257 1.00 14.91  ? 146 LEU B CD1 1 
ATOM   3952  C CD2 . LEU B 2 130 ? 161.291 192.875 183.148 1.00 15.12  ? 146 LEU B CD2 1 
ATOM   3953  N N   . PHE B 2 131 ? 164.942 192.096 179.434 1.00 22.92  ? 147 PHE B N   1 
ATOM   3954  C CA  . PHE B 2 131 ? 165.510 193.001 178.440 1.00 21.73  ? 147 PHE B CA  1 
ATOM   3955  C C   . PHE B 2 131 ? 165.374 192.432 177.034 1.00 23.18  ? 147 PHE B C   1 
ATOM   3956  O O   . PHE B 2 131 ? 165.002 193.151 176.100 1.00 26.55  ? 147 PHE B O   1 
ATOM   3957  C CB  . PHE B 2 131 ? 166.977 193.277 178.769 1.00 21.01  ? 147 PHE B CB  1 
ATOM   3958  C CG  . PHE B 2 131 ? 167.648 194.224 177.814 1.00 27.60  ? 147 PHE B CG  1 
ATOM   3959  C CD1 . PHE B 2 131 ? 167.498 195.592 177.950 1.00 24.65  ? 147 PHE B CD1 1 
ATOM   3960  C CD2 . PHE B 2 131 ? 168.441 193.744 176.785 1.00 27.21  ? 147 PHE B CD2 1 
ATOM   3961  C CE1 . PHE B 2 131 ? 168.117 196.459 177.077 1.00 22.64  ? 147 PHE B CE1 1 
ATOM   3962  C CE2 . PHE B 2 131 ? 169.062 194.610 175.910 1.00 24.12  ? 147 PHE B CE2 1 
ATOM   3963  C CZ  . PHE B 2 131 ? 168.900 195.967 176.058 1.00 22.78  ? 147 PHE B CZ  1 
ATOM   3964  N N   . GLU B 2 132 ? 165.662 191.140 176.866 1.00 22.53  ? 148 GLU B N   1 
ATOM   3965  C CA  . GLU B 2 132 ? 165.534 190.521 175.551 1.00 21.99  ? 148 GLU B CA  1 
ATOM   3966  C C   . GLU B 2 132 ? 164.086 190.506 175.084 1.00 22.46  ? 148 GLU B C   1 
ATOM   3967  O O   . GLU B 2 132 ? 163.803 190.762 173.908 1.00 27.33  ? 148 GLU B O   1 
ATOM   3968  C CB  . GLU B 2 132 ? 166.100 189.102 175.579 1.00 27.30  ? 148 GLU B CB  1 
ATOM   3969  C CG  . GLU B 2 132 ? 167.576 189.027 175.917 1.00 33.09  ? 148 GLU B CG  1 
ATOM   3970  C CD  . GLU B 2 132 ? 168.078 187.602 176.007 1.00 41.54  ? 148 GLU B CD  1 
ATOM   3971  O OE1 . GLU B 2 132 ? 167.242 186.681 176.116 1.00 43.38  ? 148 GLU B OE1 1 
ATOM   3972  O OE2 . GLU B 2 132 ? 169.310 187.402 175.971 1.00 45.26  ? 148 GLU B OE2 1 
ATOM   3973  N N   . GLU B 2 133 ? 163.152 190.205 175.989 1.00 23.11  ? 149 GLU B N   1 
ATOM   3974  C CA  . GLU B 2 133 ? 161.745 190.196 175.597 1.00 22.55  ? 149 GLU B CA  1 
ATOM   3975  C C   . GLU B 2 133 ? 161.265 191.589 175.202 1.00 21.84  ? 149 GLU B C   1 
ATOM   3976  O O   . GLU B 2 133 ? 160.533 191.744 174.216 1.00 22.24  ? 149 GLU B O   1 
ATOM   3977  C CB  . GLU B 2 133 ? 160.884 189.632 176.724 1.00 20.12  ? 149 GLU B CB  1 
ATOM   3978  C CG  . GLU B 2 133 ? 159.490 189.233 176.277 1.00 21.05  ? 149 GLU B CG  1 
ATOM   3979  C CD  . GLU B 2 133 ? 159.496 188.418 174.997 1.00 24.97  ? 149 GLU B CD  1 
ATOM   3980  O OE1 . GLU B 2 133 ? 160.254 187.429 174.919 1.00 25.25  ? 149 GLU B OE1 1 
ATOM   3981  O OE2 . GLU B 2 133 ? 158.744 188.768 174.065 1.00 22.53  ? 149 GLU B OE2 1 
ATOM   3982  N N   . CYS B 2 134 ? 161.664 192.614 175.956 1.00 20.93  ? 150 CYS B N   1 
ATOM   3983  C CA  . CYS B 2 134 ? 161.277 193.978 175.614 1.00 16.35  ? 150 CYS B CA  1 
ATOM   3984  C C   . CYS B 2 134 ? 161.902 194.414 174.295 1.00 17.69  ? 150 CYS B C   1 
ATOM   3985  O O   . CYS B 2 134 ? 161.272 195.132 173.512 1.00 18.20  ? 150 CYS B O   1 
ATOM   3986  C CB  . CYS B 2 134 ? 161.668 194.930 176.741 1.00 19.46  ? 150 CYS B CB  1 
ATOM   3987  S SG  . CYS B 2 134 ? 160.783 194.652 178.283 1.00 18.48  ? 150 CYS B SG  1 
ATOM   3988  N N   . SER B 2 135 ? 163.141 193.993 174.032 1.00 21.09  ? 151 SER B N   1 
ATOM   3989  C CA  . SER B 2 135 ? 163.773 194.297 172.754 1.00 18.73  ? 151 SER B CA  1 
ATOM   3990  C C   . SER B 2 135 ? 163.035 193.633 171.597 1.00 15.86  ? 151 SER B C   1 
ATOM   3991  O O   . SER B 2 135 ? 162.860 194.239 170.534 1.00 16.96  ? 151 SER B O   1 
ATOM   3992  C CB  . SER B 2 135 ? 165.235 193.858 172.783 1.00 19.73  ? 151 SER B CB  1 
ATOM   3993  O OG  . SER B 2 135 ? 165.657 193.410 171.510 1.00 28.60  ? 151 SER B OG  1 
ATOM   3994  N N   . ARG B 2 136 ? 162.601 192.385 171.784 1.00 15.41  ? 152 ARG B N   1 
ATOM   3995  C CA  . ARG B 2 136 ? 161.840 191.701 170.743 1.00 14.17  ? 152 ARG B CA  1 
ATOM   3996  C C   . ARG B 2 136 ? 160.498 192.383 170.498 1.00 15.44  ? 152 ARG B C   1 
ATOM   3997  O O   . ARG B 2 136 ? 160.068 192.530 169.348 1.00 14.75  ? 152 ARG B O   1 
ATOM   3998  C CB  . ARG B 2 136 ? 161.645 190.236 171.122 1.00 15.40  ? 152 ARG B CB  1 
ATOM   3999  C CG  . ARG B 2 136 ? 162.899 189.400 170.957 1.00 17.33  ? 152 ARG B CG  1 
ATOM   4000  C CD  . ARG B 2 136 ? 162.596 187.920 171.005 1.00 18.78  ? 152 ARG B CD  1 
ATOM   4001  N NE  . ARG B 2 136 ? 162.313 187.473 172.362 1.00 24.79  ? 152 ARG B NE  1 
ATOM   4002  C CZ  . ARG B 2 136 ? 163.166 186.800 173.122 1.00 29.17  ? 152 ARG B CZ  1 
ATOM   4003  N NH1 . ARG B 2 136 ? 164.373 186.479 172.688 1.00 30.21  ? 152 ARG B NH1 1 
ATOM   4004  N NH2 . ARG B 2 136 ? 162.799 186.443 174.349 1.00 28.43  ? 152 ARG B NH2 1 
ATOM   4005  N N   . PHE B 2 137 ? 159.827 192.812 171.569 1.00 17.35  ? 153 PHE B N   1 
ATOM   4006  C CA  . PHE B 2 137 ? 158.583 193.567 171.434 1.00 12.04  ? 153 PHE B CA  1 
ATOM   4007  C C   . PHE B 2 137 ? 158.809 194.863 170.658 1.00 11.83  ? 153 PHE B C   1 
ATOM   4008  O O   . PHE B 2 137 ? 158.056 195.192 169.730 1.00 14.81  ? 153 PHE B O   1 
ATOM   4009  C CB  . PHE B 2 137 ? 158.025 193.851 172.831 1.00 16.18  ? 153 PHE B CB  1 
ATOM   4010  C CG  . PHE B 2 137 ? 156.550 194.164 172.872 1.00 21.97  ? 153 PHE B CG  1 
ATOM   4011  C CD1 . PHE B 2 137 ? 155.815 194.350 171.717 1.00 19.85  ? 153 PHE B CD1 1 
ATOM   4012  C CD2 . PHE B 2 137 ? 155.901 194.277 174.089 1.00 20.51  ? 153 PHE B CD2 1 
ATOM   4013  C CE1 . PHE B 2 137 ? 154.468 194.639 171.781 1.00 16.57  ? 153 PHE B CE1 1 
ATOM   4014  C CE2 . PHE B 2 137 ? 154.558 194.566 174.152 1.00 17.84  ? 153 PHE B CE2 1 
ATOM   4015  C CZ  . PHE B 2 137 ? 153.843 194.748 172.999 1.00 18.14  ? 153 PHE B CZ  1 
ATOM   4016  N N   . LEU B 2 138 ? 159.860 195.605 171.019 1.00 14.28  ? 154 LEU B N   1 
ATOM   4017  C CA  . LEU B 2 138 ? 160.149 196.875 170.362 1.00 14.59  ? 154 LEU B CA  1 
ATOM   4018  C C   . LEU B 2 138 ? 160.475 196.678 168.888 1.00 15.11  ? 154 LEU B C   1 
ATOM   4019  O O   . LEU B 2 138 ? 160.073 197.486 168.044 1.00 17.03  ? 154 LEU B O   1 
ATOM   4020  C CB  . LEU B 2 138 ? 161.304 197.581 171.073 1.00 15.79  ? 154 LEU B CB  1 
ATOM   4021  C CG  . LEU B 2 138 ? 160.973 198.538 172.219 1.00 14.79  ? 154 LEU B CG  1 
ATOM   4022  C CD1 . LEU B 2 138 ? 162.241 199.062 172.852 1.00 14.81  ? 154 LEU B CD1 1 
ATOM   4023  C CD2 . LEU B 2 138 ? 160.118 199.688 171.730 1.00 18.33  ? 154 LEU B CD2 1 
ATOM   4024  N N   . ALA B 2 139 ? 161.218 195.619 168.559 1.00 14.94  ? 155 ALA B N   1 
ATOM   4025  C CA  . ALA B 2 139 ? 161.518 195.333 167.161 1.00 13.74  ? 155 ALA B CA  1 
ATOM   4026  C C   . ALA B 2 139 ? 160.278 194.880 166.402 1.00 16.36  ? 155 ALA B C   1 
ATOM   4027  O O   . ALA B 2 139 ? 160.170 195.120 165.195 1.00 20.79  ? 155 ALA B O   1 
ATOM   4028  C CB  . ALA B 2 139 ? 162.619 194.280 167.066 1.00 13.40  ? 155 ALA B CB  1 
ATOM   4029  N N   . ARG B 2 140 ? 159.344 194.214 167.084 1.00 15.05  ? 156 ARG B N   1 
ATOM   4030  C CA  . ARG B 2 140 ? 158.072 193.859 166.462 1.00 15.73  ? 156 ARG B CA  1 
ATOM   4031  C C   . ARG B 2 140 ? 157.274 195.099 166.082 1.00 15.33  ? 156 ARG B C   1 
ATOM   4032  O O   . ARG B 2 140 ? 156.764 195.204 164.962 1.00 16.10  ? 156 ARG B O   1 
ATOM   4033  C CB  . ARG B 2 140 ? 157.255 192.988 167.414 1.00 15.40  ? 156 ARG B CB  1 
ATOM   4034  C CG  . ARG B 2 140 ? 156.635 191.764 166.795 1.00 14.22  ? 156 ARG B CG  1 
ATOM   4035  C CD  . ARG B 2 140 ? 155.747 191.074 167.804 1.00 14.55  ? 156 ARG B CD  1 
ATOM   4036  N NE  . ARG B 2 140 ? 156.487 190.085 168.577 1.00 16.42  ? 156 ARG B NE  1 
ATOM   4037  C CZ  . ARG B 2 140 ? 156.557 190.069 169.900 1.00 16.16  ? 156 ARG B CZ  1 
ATOM   4038  N NH1 . ARG B 2 140 ? 155.921 190.963 170.635 1.00 15.49  ? 156 ARG B NH1 1 
ATOM   4039  N NH2 . ARG B 2 140 ? 157.284 189.132 170.499 1.00 15.99  ? 156 ARG B NH2 1 
ATOM   4040  N N   . THR B 2 141 ? 157.149 196.050 167.007 1.00 15.49  ? 157 THR B N   1 
ATOM   4041  C CA  . THR B 2 141 ? 156.210 197.153 166.842 1.00 16.59  ? 157 THR B CA  1 
ATOM   4042  C C   . THR B 2 141 ? 156.858 198.428 166.309 1.00 19.97  ? 157 THR B C   1 
ATOM   4043  O O   . THR B 2 141 ? 156.265 199.506 166.423 1.00 26.30  ? 157 THR B O   1 
ATOM   4044  C CB  . THR B 2 141 ? 155.499 197.440 168.164 1.00 16.02  ? 157 THR B CB  1 
ATOM   4045  O OG1 . THR B 2 141 ? 156.401 198.087 169.068 1.00 15.83  ? 157 THR B OG1 1 
ATOM   4046  C CG2 . THR B 2 141 ? 155.013 196.153 168.778 1.00 15.31  ? 157 THR B CG2 1 
ATOM   4047  N N   . VAL B 2 142 ? 158.050 198.334 165.719 1.00 21.93  ? 158 VAL B N   1 
ATOM   4048  C CA  . VAL B 2 142 ? 158.702 199.520 165.174 1.00 27.42  ? 158 VAL B CA  1 
ATOM   4049  C C   . VAL B 2 142 ? 157.992 199.954 163.896 1.00 31.99  ? 158 VAL B C   1 
ATOM   4050  O O   . VAL B 2 142 ? 157.585 199.123 163.072 1.00 29.89  ? 158 VAL B O   1 
ATOM   4051  C CB  . VAL B 2 142 ? 160.200 199.251 164.939 1.00 22.21  ? 158 VAL B CB  1 
ATOM   4052  C CG1 . VAL B 2 142 ? 160.405 198.180 163.881 1.00 21.91  ? 158 VAL B CG1 1 
ATOM   4053  C CG2 . VAL B 2 142 ? 160.921 200.532 164.561 1.00 25.41  ? 158 VAL B CG2 1 
ATOM   4054  N N   . GLN B 2 143 ? 157.816 201.265 163.737 1.00 33.71  ? 159 GLN B N   1 
ATOM   4055  C CA  . GLN B 2 143 ? 157.103 201.824 162.595 1.00 34.77  ? 159 GLN B CA  1 
ATOM   4056  C C   . GLN B 2 143 ? 157.819 203.097 162.150 1.00 35.96  ? 159 GLN B C   1 
ATOM   4057  O O   . GLN B 2 143 ? 158.952 203.369 162.556 1.00 42.41  ? 159 GLN B O   1 
ATOM   4058  C CB  . GLN B 2 143 ? 155.627 202.068 162.939 1.00 40.18  ? 159 GLN B CB  1 
ATOM   4059  C CG  . GLN B 2 143 ? 155.366 203.286 163.808 1.00 44.05  ? 159 GLN B CG  1 
ATOM   4060  C CD  . GLN B 2 143 ? 153.987 203.268 164.428 1.00 53.91  ? 159 GLN B CD  1 
ATOM   4061  O OE1 . GLN B 2 143 ? 153.076 202.614 163.922 1.00 55.69  ? 159 GLN B OE1 1 
ATOM   4062  N NE2 . GLN B 2 143 ? 153.824 203.990 165.531 1.00 59.48  ? 159 GLN B NE2 1 
ATOM   4063  N N   . VAL B 2 144 ? 157.150 203.879 161.299 1.00 37.93  ? 160 VAL B N   1 
ATOM   4064  C CA  . VAL B 2 144 ? 157.780 205.049 160.693 1.00 38.89  ? 160 VAL B CA  1 
ATOM   4065  C C   . VAL B 2 144 ? 158.001 206.149 161.725 1.00 36.65  ? 160 VAL B C   1 
ATOM   4066  O O   . VAL B 2 144 ? 159.065 206.779 161.759 1.00 36.98  ? 160 VAL B O   1 
ATOM   4067  C CB  . VAL B 2 144 ? 156.928 205.558 159.517 1.00 42.96  ? 160 VAL B CB  1 
ATOM   4068  C CG1 . VAL B 2 144 ? 157.769 206.402 158.573 1.00 41.95  ? 160 VAL B CG1 1 
ATOM   4069  C CG2 . VAL B 2 144 ? 156.268 204.400 158.796 1.00 48.21  ? 160 VAL B CG2 1 
ATOM   4070  N N   . GLY B 2 145 ? 157.003 206.408 162.571 1.00 36.01  ? 161 GLY B N   1 
ATOM   4071  C CA  . GLY B 2 145 ? 157.073 207.561 163.452 1.00 34.22  ? 161 GLY B CA  1 
ATOM   4072  C C   . GLY B 2 145 ? 158.089 207.424 164.567 1.00 39.49  ? 161 GLY B C   1 
ATOM   4073  O O   . GLY B 2 145 ? 158.584 208.429 165.085 1.00 42.83  ? 161 GLY B O   1 
ATOM   4074  N N   . ASN B 2 146 ? 158.413 206.192 164.954 1.00 38.12  ? 162 ASN B N   1 
ATOM   4075  C CA  . ASN B 2 146 ? 159.358 205.932 166.032 1.00 31.33  ? 162 ASN B CA  1 
ATOM   4076  C C   . ASN B 2 146 ? 160.637 205.273 165.540 1.00 31.53  ? 162 ASN B C   1 
ATOM   4077  O O   . ASN B 2 146 ? 161.398 204.740 166.351 1.00 39.92  ? 162 ASN B O   1 
ATOM   4078  C CB  . ASN B 2 146 ? 158.700 205.065 167.109 1.00 34.66  ? 162 ASN B CB  1 
ATOM   4079  C CG  . ASN B 2 146 ? 158.326 203.686 166.601 1.00 37.07  ? 162 ASN B CG  1 
ATOM   4080  O OD1 . ASN B 2 146 ? 158.289 203.444 165.397 1.00 35.72  ? 162 ASN B OD1 1 
ATOM   4081  N ND2 . ASN B 2 146 ? 158.042 202.774 167.521 1.00 34.43  ? 162 ASN B ND2 1 
ATOM   4082  N N   . CYS B 2 147 ? 160.891 205.297 164.233 1.00 31.26  ? 163 CYS B N   1 
ATOM   4083  C CA  . CYS B 2 147 ? 162.017 204.556 163.674 1.00 31.26  ? 163 CYS B CA  1 
ATOM   4084  C C   . CYS B 2 147 ? 163.348 205.092 164.186 1.00 35.04  ? 163 CYS B C   1 
ATOM   4085  O O   . CYS B 2 147 ? 164.180 204.338 164.704 1.00 34.30  ? 163 CYS B O   1 
ATOM   4086  C CB  . CYS B 2 147 ? 161.964 204.623 162.151 1.00 32.27  ? 163 CYS B CB  1 
ATOM   4087  S SG  . CYS B 2 147 ? 162.584 203.160 161.345 1.00 48.28  ? 163 CYS B SG  1 
ATOM   4088  N N   . LEU B 2 148 ? 163.563 206.401 164.056 1.00 39.82  ? 164 LEU B N   1 
ATOM   4089  C CA  . LEU B 2 148 ? 164.833 206.992 164.454 1.00 35.53  ? 164 LEU B CA  1 
ATOM   4090  C C   . LEU B 2 148 ? 164.988 207.045 165.967 1.00 38.70  ? 164 LEU B C   1 
ATOM   4091  O O   . LEU B 2 148 ? 166.107 206.920 166.475 1.00 43.52  ? 164 LEU B O   1 
ATOM   4092  C CB  . LEU B 2 148 ? 164.962 208.389 163.850 1.00 42.95  ? 164 LEU B CB  1 
ATOM   4093  C CG  . LEU B 2 148 ? 164.768 208.431 162.332 1.00 43.91  ? 164 LEU B CG  1 
ATOM   4094  C CD1 . LEU B 2 148 ? 164.689 209.862 161.838 1.00 56.44  ? 164 LEU B CD1 1 
ATOM   4095  C CD2 . LEU B 2 148 ? 165.879 207.677 161.624 1.00 40.49  ? 164 LEU B CD2 1 
ATOM   4096  N N   . GLN B 2 149 ? 163.886 207.217 166.699 1.00 39.10  ? 165 GLN B N   1 
ATOM   4097  C CA  . GLN B 2 149 ? 163.948 207.145 168.155 1.00 34.90  ? 165 GLN B CA  1 
ATOM   4098  C C   . GLN B 2 149 ? 164.377 205.758 168.619 1.00 33.96  ? 165 GLN B C   1 
ATOM   4099  O O   . GLN B 2 149 ? 165.205 205.624 169.528 1.00 37.17  ? 165 GLN B O   1 
ATOM   4100  C CB  . GLN B 2 149 ? 162.592 207.517 168.750 1.00 36.72  ? 165 GLN B CB  1 
ATOM   4101  C CG  . GLN B 2 149 ? 162.636 207.900 170.215 1.00 42.20  ? 165 GLN B CG  1 
ATOM   4102  C CD  . GLN B 2 149 ? 162.120 206.800 171.118 1.00 44.04  ? 165 GLN B CD  1 
ATOM   4103  O OE1 . GLN B 2 149 ? 161.084 206.193 170.847 1.00 45.45  ? 165 GLN B OE1 1 
ATOM   4104  N NE2 . GLN B 2 149 ? 162.839 206.538 172.203 1.00 39.53  ? 165 GLN B NE2 1 
ATOM   4105  N N   . VAL B 2 150 ? 163.828 204.710 168.002 1.00 31.04  ? 166 VAL B N   1 
ATOM   4106  C CA  . VAL B 2 150 ? 164.221 203.352 168.360 1.00 30.37  ? 166 VAL B CA  1 
ATOM   4107  C C   . VAL B 2 150 ? 165.662 203.082 167.938 1.00 35.22  ? 166 VAL B C   1 
ATOM   4108  O O   . VAL B 2 150 ? 166.394 202.352 168.615 1.00 37.61  ? 166 VAL B O   1 
ATOM   4109  C CB  . VAL B 2 150 ? 163.232 202.339 167.754 1.00 25.59  ? 166 VAL B CB  1 
ATOM   4110  C CG1 . VAL B 2 150 ? 163.777 200.930 167.836 1.00 25.11  ? 166 VAL B CG1 1 
ATOM   4111  C CG2 . VAL B 2 150 ? 161.906 202.419 168.475 1.00 24.48  ? 166 VAL B CG2 1 
ATOM   4112  N N   . MET B 2 151 ? 166.091 203.660 166.814 1.00 39.11  ? 167 MET B N   1 
ATOM   4113  C CA  . MET B 2 151 ? 167.494 203.557 166.415 1.00 35.82  ? 167 MET B CA  1 
ATOM   4114  C C   . MET B 2 151 ? 168.406 204.170 167.472 1.00 34.60  ? 167 MET B C   1 
ATOM   4115  O O   . MET B 2 151 ? 169.424 203.578 167.851 1.00 39.42  ? 167 MET B O   1 
ATOM   4116  C CB  . MET B 2 151 ? 167.695 204.240 165.062 1.00 39.48  ? 167 MET B CB  1 
ATOM   4117  C CG  . MET B 2 151 ? 167.870 203.284 163.900 1.00 41.15  ? 167 MET B CG  1 
ATOM   4118  S SD  . MET B 2 151 ? 168.529 204.080 162.427 1.00 45.11  ? 167 MET B SD  1 
ATOM   4119  C CE  . MET B 2 151 ? 170.271 204.136 162.813 1.00 48.49  ? 167 MET B CE  1 
ATOM   4120  N N   . TRP B 2 152 ? 168.042 205.355 167.969 1.00 36.15  ? 168 TRP B N   1 
ATOM   4121  C CA  . TRP B 2 152 ? 168.769 205.974 169.075 1.00 40.23  ? 168 TRP B CA  1 
ATOM   4122  C C   . TRP B 2 152 ? 168.788 205.078 170.305 1.00 41.20  ? 168 TRP B C   1 
ATOM   4123  O O   . TRP B 2 152 ? 169.828 204.925 170.953 1.00 44.50  ? 168 TRP B O   1 
ATOM   4124  C CB  . TRP B 2 152 ? 168.134 207.317 169.433 1.00 44.58  ? 168 TRP B CB  1 
ATOM   4125  C CG  . TRP B 2 152 ? 168.678 208.501 168.710 1.00 56.39  ? 168 TRP B CG  1 
ATOM   4126  C CD1 . TRP B 2 152 ? 167.984 209.371 167.922 1.00 56.90  ? 168 TRP B CD1 1 
ATOM   4127  C CD2 . TRP B 2 152 ? 170.023 208.990 168.761 1.00 64.74  ? 168 TRP B CD2 1 
ATOM   4128  N NE1 . TRP B 2 152 ? 168.821 210.352 167.450 1.00 61.48  ? 168 TRP B NE1 1 
ATOM   4129  C CE2 . TRP B 2 152 ? 170.078 210.142 167.953 1.00 66.28  ? 168 TRP B CE2 1 
ATOM   4130  C CE3 . TRP B 2 152 ? 171.190 208.558 169.398 1.00 59.81  ? 168 TRP B CE3 1 
ATOM   4131  C CZ2 . TRP B 2 152 ? 171.251 210.867 167.770 1.00 64.87  ? 168 TRP B CZ2 1 
ATOM   4132  C CZ3 . TRP B 2 152 ? 172.352 209.276 169.211 1.00 59.70  ? 168 TRP B CZ3 1 
ATOM   4133  C CH2 . TRP B 2 152 ? 172.375 210.418 168.405 1.00 62.37  ? 168 TRP B CH2 1 
ATOM   4134  N N   . LEU B 2 153 ? 167.638 204.502 170.656 1.00 39.63  ? 169 LEU B N   1 
ATOM   4135  C CA  . LEU B 2 153 ? 167.547 203.673 171.855 1.00 34.62  ? 169 LEU B CA  1 
ATOM   4136  C C   . LEU B 2 153 ? 168.450 202.450 171.749 1.00 33.67  ? 169 LEU B C   1 
ATOM   4137  O O   . LEU B 2 153 ? 169.200 202.131 172.678 1.00 35.87  ? 169 LEU B O   1 
ATOM   4138  C CB  . LEU B 2 153 ? 166.093 203.258 172.078 1.00 33.32  ? 169 LEU B CB  1 
ATOM   4139  C CG  . LEU B 2 153 ? 165.655 202.861 173.484 1.00 33.41  ? 169 LEU B CG  1 
ATOM   4140  C CD1 . LEU B 2 153 ? 165.699 204.056 174.413 1.00 38.74  ? 169 LEU B CD1 1 
ATOM   4141  C CD2 . LEU B 2 153 ? 164.258 202.277 173.433 1.00 27.35  ? 169 LEU B CD2 1 
ATOM   4142  N N   . ALA B 2 154 ? 168.394 201.757 170.612 1.00 35.36  ? 170 ALA B N   1 
ATOM   4143  C CA  . ALA B 2 154 ? 169.223 200.574 170.415 1.00 32.69  ? 170 ALA B CA  1 
ATOM   4144  C C   . ALA B 2 154 ? 170.702 200.932 170.381 1.00 35.52  ? 170 ALA B C   1 
ATOM   4145  O O   . ALA B 2 154 ? 171.536 200.190 170.910 1.00 38.43  ? 170 ALA B O   1 
ATOM   4146  C CB  . ALA B 2 154 ? 168.814 199.858 169.131 1.00 31.28  ? 170 ALA B CB  1 
ATOM   4147  N N   . ASP B 2 155 ? 171.052 202.058 169.755 1.00 38.61  ? 171 ASP B N   1 
ATOM   4148  C CA  . ASP B 2 155 ? 172.446 202.487 169.732 1.00 39.02  ? 171 ASP B CA  1 
ATOM   4149  C C   . ASP B 2 155 ? 172.948 202.810 171.134 1.00 41.61  ? 171 ASP B C   1 
ATOM   4150  O O   . ASP B 2 155 ? 174.072 202.447 171.499 1.00 45.29  ? 171 ASP B O   1 
ATOM   4151  C CB  . ASP B 2 155 ? 172.596 203.694 168.806 1.00 40.84  ? 171 ASP B CB  1 
ATOM   4152  C CG  . ASP B 2 155 ? 173.872 204.464 169.052 1.00 51.08  ? 171 ASP B CG  1 
ATOM   4153  O OD1 . ASP B 2 155 ? 174.956 203.937 168.729 1.00 54.78  ? 171 ASP B OD1 1 
ATOM   4154  O OD2 . ASP B 2 155 ? 173.792 205.600 169.563 1.00 53.04  ? 171 ASP B OD2 1 
ATOM   4155  N N   . ARG B 2 156 ? 172.125 203.487 171.937 1.00 41.59  ? 172 ARG B N   1 
ATOM   4156  C CA  . ARG B 2 156 ? 172.542 203.873 173.280 1.00 38.83  ? 172 ARG B CA  1 
ATOM   4157  C C   . ARG B 2 156 ? 172.638 202.667 174.205 1.00 40.10  ? 172 ARG B C   1 
ATOM   4158  O O   . ARG B 2 156 ? 173.508 202.620 175.082 1.00 44.30  ? 172 ARG B O   1 
ATOM   4159  C CB  . ARG B 2 156 ? 171.571 204.907 173.847 1.00 39.04  ? 172 ARG B CB  1 
ATOM   4160  C CG  . ARG B 2 156 ? 171.966 205.458 175.201 1.00 41.09  ? 172 ARG B CG  1 
ATOM   4161  C CD  . ARG B 2 156 ? 171.260 206.772 175.487 1.00 46.53  ? 172 ARG B CD  1 
ATOM   4162  N NE  . ARG B 2 156 ? 169.810 206.643 175.401 1.00 53.85  ? 172 ARG B NE  1 
ATOM   4163  C CZ  . ARG B 2 156 ? 169.034 207.400 174.637 1.00 57.08  ? 172 ARG B CZ  1 
ATOM   4164  N NH1 . ARG B 2 156 ? 169.535 208.363 173.881 1.00 54.45  ? 172 ARG B NH1 1 
ATOM   4165  N NH2 . ARG B 2 156 ? 167.721 207.186 174.633 1.00 51.55  ? 172 ARG B NH2 1 
ATOM   4166  N N   . HIS B 2 157 ? 171.759 201.682 174.031 1.00 39.51  ? 173 HIS B N   1 
ATOM   4167  C CA  . HIS B 2 157 ? 171.719 200.518 174.905 1.00 36.79  ? 173 HIS B CA  1 
ATOM   4168  C C   . HIS B 2 157 ? 172.455 199.316 174.329 1.00 40.39  ? 173 HIS B C   1 
ATOM   4169  O O   . HIS B 2 157 ? 172.312 198.209 174.856 1.00 41.35  ? 173 HIS B O   1 
ATOM   4170  C CB  . HIS B 2 157 ? 170.270 200.147 175.220 1.00 34.51  ? 173 HIS B CB  1 
ATOM   4171  C CG  . HIS B 2 157 ? 169.611 201.074 176.191 1.00 33.61  ? 173 HIS B CG  1 
ATOM   4172  N ND1 . HIS B 2 157 ? 169.570 200.826 177.545 1.00 34.20  ? 173 HIS B ND1 1 
ATOM   4173  C CD2 . HIS B 2 157 ? 168.975 202.254 176.005 1.00 36.46  ? 173 HIS B CD2 1 
ATOM   4174  C CE1 . HIS B 2 157 ? 168.935 201.812 178.152 1.00 35.95  ? 173 HIS B CE1 1 
ATOM   4175  N NE2 . HIS B 2 157 ? 168.563 202.691 177.240 1.00 35.47  ? 173 HIS B NE2 1 
ATOM   4176  N N   . SER B 2 158 ? 173.235 199.511 173.265 1.00 41.73  ? 174 SER B N   1 
ATOM   4177  C CA  . SER B 2 158 ? 174.056 198.458 172.664 1.00 39.31  ? 174 SER B CA  1 
ATOM   4178  C C   . SER B 2 158 ? 173.220 197.227 172.318 1.00 40.64  ? 174 SER B C   1 
ATOM   4179  O O   . SER B 2 158 ? 173.556 196.094 172.667 1.00 45.52  ? 174 SER B O   1 
ATOM   4180  C CB  . SER B 2 158 ? 175.224 198.087 173.580 1.00 43.30  ? 174 SER B CB  1 
ATOM   4181  O OG  . SER B 2 158 ? 175.710 199.221 174.275 1.00 47.70  ? 174 SER B OG  1 
ATOM   4182  N N   . ASP B 2 159 ? 172.113 197.461 171.623 1.00 38.86  ? 175 ASP B N   1 
ATOM   4183  C CA  . ASP B 2 159 ? 171.241 196.382 171.179 1.00 36.10  ? 175 ASP B CA  1 
ATOM   4184  C C   . ASP B 2 159 ? 171.427 196.176 169.684 1.00 38.07  ? 175 ASP B C   1 
ATOM   4185  O O   . ASP B 2 159 ? 170.968 197.010 168.889 1.00 39.12  ? 175 ASP B O   1 
ATOM   4186  C CB  . ASP B 2 159 ? 169.783 196.707 171.497 1.00 33.09  ? 175 ASP B CB  1 
ATOM   4187  C CG  . ASP B 2 159 ? 168.948 195.470 171.724 1.00 36.21  ? 175 ASP B CG  1 
ATOM   4188  O OD1 . ASP B 2 159 ? 169.399 194.367 171.359 1.00 40.77  ? 175 ASP B OD1 1 
ATOM   4189  O OD2 . ASP B 2 159 ? 167.836 195.602 172.269 1.00 34.39  ? 175 ASP B OD2 1 
ATOM   4190  N N   . PRO B 2 160 ? 172.090 195.103 169.250 1.00 39.13  ? 176 PRO B N   1 
ATOM   4191  C CA  . PRO B 2 160 ? 172.337 194.924 167.813 1.00 38.22  ? 176 PRO B CA  1 
ATOM   4192  C C   . PRO B 2 160 ? 171.089 194.576 167.019 1.00 40.80  ? 176 PRO B C   1 
ATOM   4193  O O   . PRO B 2 160 ? 170.845 195.167 165.965 1.00 41.78  ? 176 PRO B O   1 
ATOM   4194  C CB  . PRO B 2 160 ? 173.359 193.781 167.774 1.00 41.43  ? 176 PRO B CB  1 
ATOM   4195  C CG  . PRO B 2 160 ? 173.168 193.049 169.053 1.00 45.80  ? 176 PRO B CG  1 
ATOM   4196  C CD  . PRO B 2 160 ? 172.737 194.062 170.066 1.00 43.94  ? 176 PRO B CD  1 
ATOM   4197  N N   . GLU B 2 161 ? 170.289 193.627 167.513 1.00 38.05  ? 177 GLU B N   1 
ATOM   4198  C CA  . GLU B 2 161 ? 169.120 193.174 166.763 1.00 37.01  ? 177 GLU B CA  1 
ATOM   4199  C C   . GLU B 2 161 ? 168.068 194.270 166.643 1.00 38.14  ? 177 GLU B C   1 
ATOM   4200  O O   . GLU B 2 161 ? 167.480 194.462 165.570 1.00 40.41  ? 177 GLU B O   1 
ATOM   4201  C CB  . GLU B 2 161 ? 168.528 191.930 167.424 1.00 42.68  ? 177 GLU B CB  1 
ATOM   4202  C CG  . GLU B 2 161 ? 169.549 190.852 167.751 1.00 48.04  ? 177 GLU B CG  1 
ATOM   4203  C CD  . GLU B 2 161 ? 170.126 190.985 169.147 1.00 53.57  ? 177 GLU B CD  1 
ATOM   4204  O OE1 . GLU B 2 161 ? 169.658 191.857 169.909 1.00 50.22  ? 177 GLU B OE1 1 
ATOM   4205  O OE2 . GLU B 2 161 ? 171.046 190.212 169.485 1.00 60.06  ? 177 GLU B OE2 1 
ATOM   4206  N N   . LEU B 2 162 ? 167.811 194.995 167.733 1.00 33.39  ? 178 LEU B N   1 
ATOM   4207  C CA  . LEU B 2 162 ? 166.878 196.113 167.668 1.00 30.23  ? 178 LEU B CA  1 
ATOM   4208  C C   . LEU B 2 162 ? 167.393 197.191 166.725 1.00 35.15  ? 178 LEU B C   1 
ATOM   4209  O O   . LEU B 2 162 ? 166.615 197.810 165.988 1.00 40.37  ? 178 LEU B O   1 
ATOM   4210  C CB  . LEU B 2 162 ? 166.648 196.682 169.067 1.00 26.09  ? 178 LEU B CB  1 
ATOM   4211  C CG  . LEU B 2 162 ? 165.610 197.792 169.218 1.00 22.68  ? 178 LEU B CG  1 
ATOM   4212  C CD1 . LEU B 2 162 ? 164.329 197.403 168.521 1.00 23.00  ? 178 LEU B CD1 1 
ATOM   4213  C CD2 . LEU B 2 162 ? 165.356 198.086 170.676 1.00 22.30  ? 178 LEU B CD2 1 
ATOM   4214  N N   . TYR B 2 163 ? 168.706 197.430 166.740 1.00 34.84  ? 179 TYR B N   1 
ATOM   4215  C CA  . TYR B 2 163 ? 169.305 198.369 165.799 1.00 35.16  ? 179 TYR B CA  1 
ATOM   4216  C C   . TYR B 2 163 ? 169.063 197.953 164.356 1.00 36.01  ? 179 TYR B C   1 
ATOM   4217  O O   . TYR B 2 163 ? 168.684 198.782 163.527 1.00 37.83  ? 179 TYR B O   1 
ATOM   4218  C CB  . TYR B 2 163 ? 170.803 198.494 166.065 1.00 38.60  ? 179 TYR B CB  1 
ATOM   4219  C CG  . TYR B 2 163 ? 171.435 199.712 165.437 1.00 40.51  ? 179 TYR B CG  1 
ATOM   4220  C CD1 . TYR B 2 163 ? 171.485 200.926 166.105 1.00 39.58  ? 179 TYR B CD1 1 
ATOM   4221  C CD2 . TYR B 2 163 ? 171.989 199.639 164.168 1.00 44.80  ? 179 TYR B CD2 1 
ATOM   4222  C CE1 . TYR B 2 163 ? 172.069 202.031 165.522 1.00 44.15  ? 179 TYR B CE1 1 
ATOM   4223  C CE2 . TYR B 2 163 ? 172.570 200.735 163.580 1.00 49.04  ? 179 TYR B CE2 1 
ATOM   4224  C CZ  . TYR B 2 163 ? 172.610 201.926 164.260 1.00 53.53  ? 179 TYR B CZ  1 
ATOM   4225  O OH  . TYR B 2 163 ? 173.193 203.016 163.667 1.00 62.35  ? 179 TYR B OH  1 
ATOM   4226  N N   . THR B 2 164 ? 169.287 196.678 164.030 1.00 36.42  ? 180 THR B N   1 
ATOM   4227  C CA  . THR B 2 164 ? 169.068 196.245 162.654 1.00 37.79  ? 180 THR B CA  1 
ATOM   4228  C C   . THR B 2 164 ? 167.597 196.333 162.272 1.00 38.87  ? 180 THR B C   1 
ATOM   4229  O O   . THR B 2 164 ? 167.274 196.699 161.140 1.00 42.85  ? 180 THR B O   1 
ATOM   4230  C CB  . THR B 2 164 ? 169.598 194.829 162.431 1.00 40.66  ? 180 THR B CB  1 
ATOM   4231  O OG1 . THR B 2 164 ? 168.713 193.874 163.029 1.00 41.37  ? 180 THR B OG1 1 
ATOM   4232  C CG2 . THR B 2 164 ? 170.995 194.677 162.994 1.00 40.14  ? 180 THR B CG2 1 
ATOM   4233  N N   . ALA B 2 165 ? 166.691 196.014 163.199 1.00 37.99  ? 181 ALA B N   1 
ATOM   4234  C CA  . ALA B 2 165 ? 165.264 196.132 162.904 1.00 35.22  ? 181 ALA B CA  1 
ATOM   4235  C C   . ALA B 2 165 ? 164.875 197.578 162.608 1.00 36.15  ? 181 ALA B C   1 
ATOM   4236  O O   . ALA B 2 165 ? 164.215 197.868 161.600 1.00 36.11  ? 181 ALA B O   1 
ATOM   4237  C CB  . ALA B 2 165 ? 164.444 195.582 164.070 1.00 28.61  ? 181 ALA B CB  1 
ATOM   4238  N N   . ALA B 2 166 ? 165.296 198.506 163.472 1.00 37.92  ? 182 ALA B N   1 
ATOM   4239  C CA  . ALA B 2 166 ? 164.973 199.914 163.268 1.00 33.97  ? 182 ALA B CA  1 
ATOM   4240  C C   . ALA B 2 166 ? 165.626 200.458 162.004 1.00 39.03  ? 182 ALA B C   1 
ATOM   4241  O O   . ALA B 2 166 ? 165.024 201.259 161.282 1.00 42.52  ? 182 ALA B O   1 
ATOM   4242  C CB  . ALA B 2 166 ? 165.403 200.731 164.485 1.00 31.59  ? 182 ALA B CB  1 
ATOM   4243  N N   . LYS B 2 167 ? 166.858 200.036 161.718 1.00 42.46  ? 183 LYS B N   1 
ATOM   4244  C CA  . LYS B 2 167 ? 167.558 200.529 160.538 1.00 44.31  ? 183 LYS B CA  1 
ATOM   4245  C C   . LYS B 2 167 ? 166.947 199.974 159.257 1.00 46.43  ? 183 LYS B C   1 
ATOM   4246  O O   . LYS B 2 167 ? 166.876 200.676 158.243 1.00 52.09  ? 183 LYS B O   1 
ATOM   4247  C CB  . LYS B 2 167 ? 169.042 200.180 160.647 1.00 44.31  ? 183 LYS B CB  1 
ATOM   4248  C CG  . LYS B 2 167 ? 169.734 199.868 159.343 1.00 50.60  ? 183 LYS B CG  1 
ATOM   4249  C CD  . LYS B 2 167 ? 171.226 199.706 159.561 1.00 54.38  ? 183 LYS B CD  1 
ATOM   4250  C CE  . LYS B 2 167 ? 171.536 198.446 160.345 1.00 49.49  ? 183 LYS B CE  1 
ATOM   4251  N NZ  . LYS B 2 167 ? 171.422 197.227 159.501 1.00 48.32  ? 183 LYS B NZ  1 
ATOM   4252  N N   . HIS B 2 168 ? 166.491 198.719 159.285 1.00 42.35  ? 184 HIS B N   1 
ATOM   4253  C CA  . HIS B 2 168 ? 165.779 198.157 158.145 1.00 43.57  ? 184 HIS B CA  1 
ATOM   4254  C C   . HIS B 2 168 ? 164.464 198.887 157.920 1.00 45.70  ? 184 HIS B C   1 
ATOM   4255  O O   . HIS B 2 168 ? 164.069 199.130 156.775 1.00 49.40  ? 184 HIS B O   1 
ATOM   4256  C CB  . HIS B 2 168 ? 165.564 196.655 158.368 1.00 48.38  ? 184 HIS B CB  1 
ATOM   4257  C CG  . HIS B 2 168 ? 164.670 195.988 157.362 1.00 51.56  ? 184 HIS B CG  1 
ATOM   4258  N ND1 . HIS B 2 168 ? 163.398 196.432 157.066 1.00 49.42  ? 184 HIS B ND1 1 
ATOM   4259  C CD2 . HIS B 2 168 ? 164.873 194.898 156.584 1.00 53.34  ? 184 HIS B CD2 1 
ATOM   4260  C CE1 . HIS B 2 168 ? 162.859 195.647 156.150 1.00 53.45  ? 184 HIS B CE1 1 
ATOM   4261  N NE2 . HIS B 2 168 ? 163.734 194.708 155.841 1.00 57.11  ? 184 HIS B NE2 1 
ATOM   4262  N N   . CYS B 2 169 ? 163.763 199.235 159.001 1.00 47.59  ? 185 CYS B N   1 
ATOM   4263  C CA  . CYS B 2 169 ? 162.522 199.985 158.838 1.00 46.15  ? 185 CYS B CA  1 
ATOM   4264  C C   . CYS B 2 169 ? 162.783 201.406 158.350 1.00 44.97  ? 185 CYS B C   1 
ATOM   4265  O O   . CYS B 2 169 ? 161.937 201.990 157.666 1.00 46.14  ? 185 CYS B O   1 
ATOM   4266  C CB  . CYS B 2 169 ? 161.740 200.000 160.152 1.00 38.83  ? 185 CYS B CB  1 
ATOM   4267  S SG  . CYS B 2 169 ? 160.178 200.899 160.087 1.00 43.29  ? 185 CYS B SG  1 
ATOM   4268  N N   . ALA B 2 170 ? 163.941 201.978 158.689 1.00 45.90  ? 186 ALA B N   1 
ATOM   4269  C CA  . ALA B 2 170 ? 164.260 203.338 158.270 1.00 47.18  ? 186 ALA B CA  1 
ATOM   4270  C C   . ALA B 2 170 ? 164.685 203.416 156.811 1.00 52.30  ? 186 ALA B C   1 
ATOM   4271  O O   . ALA B 2 170 ? 164.417 204.422 156.147 1.00 56.52  ? 186 ALA B O   1 
ATOM   4272  C CB  . ALA B 2 170 ? 165.358 203.921 159.161 1.00 45.42  ? 186 ALA B CB  1 
ATOM   4273  N N   . LYS B 2 171 ? 165.354 202.381 156.298 1.00 53.62  ? 187 LYS B N   1 
ATOM   4274  C CA  . LYS B 2 171 ? 165.834 202.426 154.922 1.00 52.66  ? 187 LYS B CA  1 
ATOM   4275  C C   . LYS B 2 171 ? 164.694 202.287 153.920 1.00 53.64  ? 187 LYS B C   1 
ATOM   4276  O O   . LYS B 2 171 ? 164.770 202.847 152.821 1.00 62.36  ? 187 LYS B O   1 
ATOM   4277  C CB  . LYS B 2 171 ? 166.887 201.338 154.696 1.00 55.01  ? 187 LYS B CB  1 
ATOM   4278  C CG  . LYS B 2 171 ? 166.323 199.978 154.318 1.00 58.01  ? 187 LYS B CG  1 
ATOM   4279  C CD  . LYS B 2 171 ? 167.376 198.889 154.377 1.00 60.65  ? 187 LYS B CD  1 
ATOM   4280  C CE  . LYS B 2 171 ? 166.745 197.508 154.400 1.00 63.57  ? 187 LYS B CE  1 
ATOM   4281  N NZ  . LYS B 2 171 ? 167.041 196.743 153.159 1.00 64.69  ? 187 LYS B NZ  1 
ATOM   4282  N N   . THR B 2 172 ? 163.634 201.563 154.273 1.00 52.24  ? 188 THR B N   1 
ATOM   4283  C CA  . THR B 2 172 ? 162.545 201.301 153.343 1.00 56.94  ? 188 THR B CA  1 
ATOM   4284  C C   . THR B 2 172 ? 161.499 202.408 153.302 1.00 58.50  ? 188 THR B C   1 
ATOM   4285  O O   . THR B 2 172 ? 160.654 202.402 152.403 1.00 63.41  ? 188 THR B O   1 
ATOM   4286  C CB  . THR B 2 172 ? 161.870 199.966 153.683 1.00 56.83  ? 188 THR B CB  1 
ATOM   4287  O OG1 . THR B 2 172 ? 161.231 200.058 154.960 1.00 57.29  ? 188 THR B OG1 1 
ATOM   4288  C CG2 . THR B 2 172 ? 162.894 198.845 153.715 1.00 55.20  ? 188 THR B CG2 1 
ATOM   4289  N N   . HIS B 2 173 ? 161.527 203.347 154.244 1.00 56.65  ? 189 HIS B N   1 
ATOM   4290  C CA  . HIS B 2 173 ? 160.654 204.516 154.234 1.00 60.01  ? 189 HIS B CA  1 
ATOM   4291  C C   . HIS B 2 173 ? 161.474 205.799 154.242 1.00 63.04  ? 189 HIS B C   1 
ATOM   4292  O O   . HIS B 2 173 ? 161.104 206.789 154.873 1.00 66.29  ? 189 HIS B O   1 
ATOM   4293  C CB  . HIS B 2 173 ? 159.680 204.517 155.414 1.00 59.77  ? 189 HIS B CB  1 
ATOM   4294  C CG  . HIS B 2 173 ? 158.843 203.279 155.538 1.00 60.10  ? 189 HIS B CG  1 
ATOM   4295  N ND1 . HIS B 2 173 ? 159.253 202.063 155.038 1.00 64.31  ? 189 HIS B ND1 1 
ATOM   4296  C CD2 . HIS B 2 173 ? 157.622 203.066 156.083 1.00 57.37  ? 189 HIS B CD2 1 
ATOM   4297  C CE1 . HIS B 2 173 ? 158.327 201.153 155.277 1.00 64.11  ? 189 HIS B CE1 1 
ATOM   4298  N NE2 . HIS B 2 173 ? 157.326 201.736 155.910 1.00 62.56  ? 189 HIS B NE2 1 
ATOM   4299  N N   . LEU B 2 174 ? 162.607 205.794 153.538 1.00 62.64  ? 190 LEU B N   1 
ATOM   4300  C CA  . LEU B 2 174 ? 163.505 206.945 153.572 1.00 67.24  ? 190 LEU B CA  1 
ATOM   4301  C C   . LEU B 2 174 ? 162.881 208.178 152.930 1.00 74.00  ? 190 LEU B C   1 
ATOM   4302  O O   . LEU B 2 174 ? 163.186 209.304 153.338 1.00 74.02  ? 190 LEU B O   1 
ATOM   4303  C CB  . LEU B 2 174 ? 164.825 206.601 152.882 1.00 66.21  ? 190 LEU B CB  1 
ATOM   4304  C CG  . LEU B 2 174 ? 165.972 207.587 153.105 1.00 70.83  ? 190 LEU B CG  1 
ATOM   4305  C CD1 . LEU B 2 174 ? 166.306 207.696 154.583 1.00 69.17  ? 190 LEU B CD1 1 
ATOM   4306  C CD2 . LEU B 2 174 ? 167.194 207.178 152.308 1.00 75.79  ? 190 LEU B CD2 1 
ATOM   4307  N N   . ALA B 2 175 ? 162.017 207.991 151.930 1.00 74.31  ? 191 ALA B N   1 
ATOM   4308  C CA  . ALA B 2 175 ? 161.416 209.131 151.245 1.00 72.20  ? 191 ALA B CA  1 
ATOM   4309  C C   . ALA B 2 175 ? 160.551 209.957 152.189 1.00 75.61  ? 191 ALA B C   1 
ATOM   4310  O O   . ALA B 2 175 ? 160.581 211.192 152.149 1.00 77.23  ? 191 ALA B O   1 
ATOM   4311  C CB  . ALA B 2 175 ? 160.597 208.652 150.049 1.00 69.01  ? 191 ALA B CB  1 
ATOM   4312  N N   . GLN B 2 176 ? 159.769 209.294 153.043 1.00 73.96  ? 192 GLN B N   1 
ATOM   4313  C CA  . GLN B 2 176 ? 158.929 210.014 153.992 1.00 69.94  ? 192 GLN B CA  1 
ATOM   4314  C C   . GLN B 2 176 ? 159.731 210.622 155.132 1.00 73.30  ? 192 GLN B C   1 
ATOM   4315  O O   . GLN B 2 176 ? 159.255 211.564 155.774 1.00 77.18  ? 192 GLN B O   1 
ATOM   4316  C CB  . GLN B 2 176 ? 157.857 209.085 154.560 1.00 68.52  ? 192 GLN B CB  1 
ATOM   4317  C CG  . GLN B 2 176 ? 156.985 208.424 153.511 1.00 70.15  ? 192 GLN B CG  1 
ATOM   4318  C CD  . GLN B 2 176 ? 156.459 207.076 153.958 1.00 67.93  ? 192 GLN B CD  1 
ATOM   4319  O OE1 . GLN B 2 176 ? 155.636 206.988 154.868 1.00 67.47  ? 192 GLN B OE1 1 
ATOM   4320  N NE2 . GLN B 2 176 ? 156.935 206.015 153.318 1.00 70.02  ? 192 GLN B NE2 1 
ATOM   4321  N N   . LEU B 2 177 ? 160.932 210.107 155.399 1.00 72.84  ? 193 LEU B N   1 
ATOM   4322  C CA  . LEU B 2 177 ? 161.726 210.579 156.526 1.00 74.75  ? 193 LEU B CA  1 
ATOM   4323  C C   . LEU B 2 177 ? 162.405 211.916 156.262 1.00 74.33  ? 193 LEU B C   1 
ATOM   4324  O O   . LEU B 2 177 ? 162.760 212.609 157.220 1.00 75.22  ? 193 LEU B O   1 
ATOM   4325  C CB  . LEU B 2 177 ? 162.784 209.536 156.892 1.00 71.31  ? 193 LEU B CB  1 
ATOM   4326  C CG  . LEU B 2 177 ? 162.528 208.693 158.142 1.00 65.32  ? 193 LEU B CG  1 
ATOM   4327  C CD1 . LEU B 2 177 ? 161.343 207.769 157.938 1.00 59.02  ? 193 LEU B CD1 1 
ATOM   4328  C CD2 . LEU B 2 177 ? 163.769 207.899 158.508 1.00 65.07  ? 193 LEU B CD2 1 
ATOM   4329  N N   . GLN B 2 178 ? 162.584 212.297 154.994 1.00 76.32  ? 194 GLN B N   1 
ATOM   4330  C CA  . GLN B 2 178 ? 163.367 213.489 154.677 1.00 79.61  ? 194 GLN B CA  1 
ATOM   4331  C C   . GLN B 2 178 ? 162.714 214.754 155.220 1.00 80.68  ? 194 GLN B C   1 
ATOM   4332  O O   . GLN B 2 178 ? 163.404 215.651 155.718 1.00 79.99  ? 194 GLN B O   1 
ATOM   4333  C CB  . GLN B 2 178 ? 163.566 213.601 153.167 1.00 80.95  ? 194 GLN B CB  1 
ATOM   4334  C CG  . GLN B 2 178 ? 164.115 212.347 152.515 1.00 84.17  ? 194 GLN B CG  1 
ATOM   4335  C CD  . GLN B 2 178 ? 163.998 212.381 151.005 1.00 88.13  ? 194 GLN B CD  1 
ATOM   4336  O OE1 . GLN B 2 178 ? 164.611 211.575 150.305 1.00 89.07  ? 194 GLN B OE1 1 
ATOM   4337  N NE2 . GLN B 2 178 ? 163.209 213.319 150.494 1.00 84.75  ? 194 GLN B NE2 1 
ATOM   4338  N N   . ASN B 2 179 ? 161.390 214.847 155.134 1.00 80.74  ? 195 ASN B N   1 
ATOM   4339  C CA  . ASN B 2 179 ? 160.668 216.039 155.563 1.00 81.83  ? 195 ASN B CA  1 
ATOM   4340  C C   . ASN B 2 179 ? 160.548 216.155 157.078 1.00 81.87  ? 195 ASN B C   1 
ATOM   4341  O O   . ASN B 2 179 ? 159.784 216.999 157.559 1.00 84.16  ? 195 ASN B O   1 
ATOM   4342  C CB  . ASN B 2 179 ? 159.273 216.062 154.932 1.00 83.74  ? 195 ASN B CB  1 
ATOM   4343  C CG  . ASN B 2 179 ? 159.279 215.601 153.489 1.00 84.80  ? 195 ASN B CG  1 
ATOM   4344  O OD1 . ASN B 2 179 ? 160.259 215.790 152.768 1.00 83.29  ? 195 ASN B OD1 1 
ATOM   4345  N ND2 . ASN B 2 179 ? 158.180 214.991 153.058 1.00 83.92  ? 195 ASN B ND2 1 
ATOM   4346  N N   . THR B 2 180 ? 161.274 215.340 157.836 1.00 80.06  ? 196 THR B N   1 
ATOM   4347  C CA  . THR B 2 180 ? 161.188 215.320 159.288 1.00 79.67  ? 196 THR B CA  1 
ATOM   4348  C C   . THR B 2 180 ? 162.466 215.882 159.894 1.00 79.15  ? 196 THR B C   1 
ATOM   4349  O O   . THR B 2 180 ? 163.567 215.607 159.409 1.00 80.76  ? 196 THR B O   1 
ATOM   4350  C CB  . THR B 2 180 ? 160.952 213.897 159.802 1.00 81.04  ? 196 THR B CB  1 
ATOM   4351  O OG1 . THR B 2 180 ? 162.060 213.067 159.434 1.00 80.06  ? 196 THR B OG1 1 
ATOM   4352  C CG2 . THR B 2 180 ? 159.677 213.321 159.207 1.00 77.75  ? 196 THR B CG2 1 
ATOM   4353  N N   . GLU B 2 181 ? 162.313 216.675 160.957 1.00 81.64  ? 197 GLU B N   1 
ATOM   4354  C CA  . GLU B 2 181 ? 163.477 217.256 161.619 1.00 83.00  ? 197 GLU B CA  1 
ATOM   4355  C C   . GLU B 2 181 ? 164.318 216.196 162.318 1.00 81.14  ? 197 GLU B C   1 
ATOM   4356  O O   . GLU B 2 181 ? 165.537 216.363 162.451 1.00 82.79  ? 197 GLU B O   1 
ATOM   4357  C CB  . GLU B 2 181 ? 163.037 218.326 162.618 1.00 80.68  ? 197 GLU B CB  1 
ATOM   4358  C CG  . GLU B 2 181 ? 162.114 219.377 162.031 1.00 84.60  ? 197 GLU B CG  1 
ATOM   4359  C CD  . GLU B 2 181 ? 162.803 220.237 160.990 1.00 88.15  ? 197 GLU B CD  1 
ATOM   4360  O OE1 . GLU B 2 181 ? 162.322 220.280 159.838 1.00 86.40  ? 197 GLU B OE1 1 
ATOM   4361  O OE2 . GLU B 2 181 ? 163.828 220.867 161.323 1.00 89.69  ? 197 GLU B OE2 1 
ATOM   4362  N N   . GLU B 2 182 ? 163.692 215.110 162.776 1.00 78.74  ? 198 GLU B N   1 
ATOM   4363  C CA  . GLU B 2 182 ? 164.435 214.045 163.437 1.00 75.86  ? 198 GLU B CA  1 
ATOM   4364  C C   . GLU B 2 182 ? 165.416 213.358 162.498 1.00 75.52  ? 198 GLU B C   1 
ATOM   4365  O O   . GLU B 2 182 ? 166.417 212.805 162.966 1.00 76.85  ? 198 GLU B O   1 
ATOM   4366  C CB  . GLU B 2 182 ? 163.467 213.019 164.027 1.00 72.96  ? 198 GLU B CB  1 
ATOM   4367  C CG  . GLU B 2 182 ? 163.942 212.405 165.332 1.00 72.84  ? 198 GLU B CG  1 
ATOM   4368  C CD  . GLU B 2 182 ? 162.877 211.558 165.998 1.00 75.55  ? 198 GLU B CD  1 
ATOM   4369  O OE1 . GLU B 2 182 ? 162.793 211.583 167.243 1.00 77.27  ? 198 GLU B OE1 1 
ATOM   4370  O OE2 . GLU B 2 182 ? 162.125 210.869 165.279 1.00 71.65  ? 198 GLU B OE2 1 
ATOM   4371  N N   . PHE B 2 183 ? 165.152 213.375 161.190 1.00 73.53  ? 199 PHE B N   1 
ATOM   4372  C CA  . PHE B 2 183 ? 166.115 212.843 160.232 1.00 71.90  ? 199 PHE B CA  1 
ATOM   4373  C C   . PHE B 2 183 ? 167.209 213.855 159.923 1.00 75.99  ? 199 PHE B C   1 
ATOM   4374  O O   . PHE B 2 183 ? 168.369 213.479 159.729 1.00 78.94  ? 199 PHE B O   1 
ATOM   4375  C CB  . PHE B 2 183 ? 165.404 212.422 158.948 1.00 69.59  ? 199 PHE B CB  1 
ATOM   4376  C CG  . PHE B 2 183 ? 166.337 212.112 157.813 1.00 69.78  ? 199 PHE B CG  1 
ATOM   4377  C CD1 . PHE B 2 183 ? 166.939 210.872 157.716 1.00 67.32  ? 199 PHE B CD1 1 
ATOM   4378  C CD2 . PHE B 2 183 ? 166.604 213.059 156.839 1.00 73.82  ? 199 PHE B CD2 1 
ATOM   4379  C CE1 . PHE B 2 183 ? 167.793 210.583 156.675 1.00 68.15  ? 199 PHE B CE1 1 
ATOM   4380  C CE2 . PHE B 2 183 ? 167.458 212.775 155.796 1.00 75.03  ? 199 PHE B CE2 1 
ATOM   4381  C CZ  . PHE B 2 183 ? 168.053 211.535 155.714 1.00 71.53  ? 199 PHE B CZ  1 
ATOM   4382  N N   . LEU B 2 184 ? 166.858 215.140 159.860 1.00 79.27  ? 200 LEU B N   1 
ATOM   4383  C CA  . LEU B 2 184 ? 167.860 216.170 159.622 1.00 81.50  ? 200 LEU B CA  1 
ATOM   4384  C C   . LEU B 2 184 ? 168.815 216.329 160.796 1.00 81.80  ? 200 LEU B C   1 
ATOM   4385  O O   . LEU B 2 184 ? 169.946 216.786 160.601 1.00 84.99  ? 200 LEU B O   1 
ATOM   4386  C CB  . LEU B 2 184 ? 167.177 217.504 159.320 1.00 82.42  ? 200 LEU B CB  1 
ATOM   4387  C CG  . LEU B 2 184 ? 166.315 217.554 158.058 1.00 79.73  ? 200 LEU B CG  1 
ATOM   4388  C CD1 . LEU B 2 184 ? 166.057 218.990 157.643 1.00 85.43  ? 200 LEU B CD1 1 
ATOM   4389  C CD2 . LEU B 2 184 ? 166.975 216.786 156.927 1.00 81.21  ? 200 LEU B CD2 1 
ATOM   4390  N N   . HIS B 2 185 ? 168.392 215.960 162.003 1.00 79.49  ? 201 HIS B N   1 
ATOM   4391  C CA  . HIS B 2 185 ? 169.203 216.160 163.195 1.00 80.74  ? 201 HIS B CA  1 
ATOM   4392  C C   . HIS B 2 185 ? 170.049 214.951 163.572 1.00 77.96  ? 201 HIS B C   1 
ATOM   4393  O O   . HIS B 2 185 ? 170.918 215.078 164.441 1.00 77.85  ? 201 HIS B O   1 
ATOM   4394  C CB  . HIS B 2 185 ? 168.308 216.533 164.380 1.00 81.93  ? 201 HIS B CB  1 
ATOM   4395  C CG  . HIS B 2 185 ? 167.985 217.992 164.457 1.00 84.63  ? 201 HIS B CG  1 
ATOM   4396  N ND1 . HIS B 2 185 ? 167.131 218.611 163.571 1.00 87.10  ? 201 HIS B ND1 1 
ATOM   4397  C CD2 . HIS B 2 185 ? 168.399 218.954 165.315 1.00 85.84  ? 201 HIS B CD2 1 
ATOM   4398  C CE1 . HIS B 2 185 ? 167.033 219.892 163.879 1.00 88.36  ? 201 HIS B CE1 1 
ATOM   4399  N NE2 . HIS B 2 185 ? 167.793 220.126 164.933 1.00 89.77  ? 201 HIS B NE2 1 
ATOM   4400  N N   . LEU B 2 186 ? 169.826 213.790 162.960 1.00 76.79  ? 202 LEU B N   1 
ATOM   4401  C CA  . LEU B 2 186 ? 170.610 212.622 163.323 1.00 79.42  ? 202 LEU B CA  1 
ATOM   4402  C C   . LEU B 2 186 ? 172.049 212.780 162.830 1.00 79.52  ? 202 LEU B C   1 
ATOM   4403  O O   . LEU B 2 186 ? 172.295 213.411 161.800 1.00 81.66  ? 202 LEU B O   1 
ATOM   4404  C CB  . LEU B 2 186 ? 169.983 211.344 162.762 1.00 74.33  ? 202 LEU B CB  1 
ATOM   4405  C CG  . LEU B 2 186 ? 169.812 211.098 161.264 1.00 70.05  ? 202 LEU B CG  1 
ATOM   4406  C CD1 . LEU B 2 186 ? 171.043 210.454 160.659 1.00 73.76  ? 202 LEU B CD1 1 
ATOM   4407  C CD2 . LEU B 2 186 ? 168.601 210.218 161.035 1.00 64.34  ? 202 LEU B CD2 1 
ATOM   4408  N N   . PRO B 2 187 ? 173.022 212.215 163.552 1.00 77.45  ? 203 PRO B N   1 
ATOM   4409  C CA  . PRO B 2 187 ? 174.427 212.471 163.212 1.00 77.73  ? 203 PRO B CA  1 
ATOM   4410  C C   . PRO B 2 187 ? 174.895 211.681 162.004 1.00 80.72  ? 203 PRO B C   1 
ATOM   4411  O O   . PRO B 2 187 ? 174.116 210.981 161.351 1.00 81.39  ? 203 PRO B O   1 
ATOM   4412  C CB  . PRO B 2 187 ? 175.190 212.055 164.478 1.00 78.48  ? 203 PRO B CB  1 
ATOM   4413  C CG  . PRO B 2 187 ? 174.207 211.366 165.368 1.00 72.93  ? 203 PRO B CG  1 
ATOM   4414  C CD  . PRO B 2 187 ? 172.882 211.288 164.686 1.00 73.41  ? 203 PRO B CD  1 
ATOM   4415  N N   . HIS B 2 188 ? 176.188 211.798 161.707 1.00 80.16  ? 204 HIS B N   1 
ATOM   4416  C CA  . HIS B 2 188 ? 176.739 211.196 160.500 1.00 81.68  ? 204 HIS B CA  1 
ATOM   4417  C C   . HIS B 2 188 ? 176.753 209.674 160.582 1.00 78.00  ? 204 HIS B C   1 
ATOM   4418  O O   . HIS B 2 188 ? 176.367 208.995 159.623 1.00 77.54  ? 204 HIS B O   1 
ATOM   4419  C CB  . HIS B 2 188 ? 178.137 211.768 160.251 1.00 87.51  ? 204 HIS B CB  1 
ATOM   4420  C CG  . HIS B 2 188 ? 178.832 211.199 159.054 1.00 93.54  ? 204 HIS B CG  1 
ATOM   4421  N ND1 . HIS B 2 188 ? 179.277 211.981 158.011 1.00 98.00  ? 204 HIS B ND1 1 
ATOM   4422  C CD2 . HIS B 2 188 ? 179.229 209.937 158.771 1.00 90.73  ? 204 HIS B CD2 1 
ATOM   4423  C CE1 . HIS B 2 188 ? 179.868 211.215 157.110 1.00 98.54  ? 204 HIS B CE1 1 
ATOM   4424  N NE2 . HIS B 2 188 ? 179.854 209.971 157.549 1.00 94.60  ? 204 HIS B NE2 1 
ATOM   4425  N N   . ARG B 2 189 ? 177.173 209.118 161.722 1.00 75.87  ? 205 ARG B N   1 
ATOM   4426  C CA  . ARG B 2 189 ? 177.394 207.676 161.805 1.00 74.13  ? 205 ARG B CA  1 
ATOM   4427  C C   . ARG B 2 189 ? 176.101 206.885 161.618 1.00 74.39  ? 205 ARG B C   1 
ATOM   4428  O O   . ARG B 2 189 ? 176.077 205.897 160.870 1.00 75.53  ? 205 ARG B O   1 
ATOM   4429  C CB  . ARG B 2 189 ? 178.058 207.329 163.136 1.00 69.61  ? 205 ARG B CB  1 
ATOM   4430  C CG  . ARG B 2 189 ? 177.408 207.974 164.348 1.00 72.03  ? 205 ARG B CG  1 
ATOM   4431  C CD  . ARG B 2 189 ? 177.617 207.124 165.586 1.00 69.77  ? 205 ARG B CD  1 
ATOM   4432  N NE  . ARG B 2 189 ? 176.773 205.936 165.566 1.00 69.65  ? 205 ARG B NE  1 
ATOM   4433  C CZ  . ARG B 2 189 ? 177.212 204.706 165.794 1.00 69.31  ? 205 ARG B CZ  1 
ATOM   4434  N NH1 . ARG B 2 189 ? 178.484 204.466 166.062 1.00 71.39  ? 205 ARG B NH1 1 
ATOM   4435  N NH2 . ARG B 2 189 ? 176.355 203.691 165.737 1.00 64.83  ? 205 ARG B NH2 1 
ATOM   4436  N N   . LEU B 2 190 ? 175.018 207.299 162.280 1.00 73.03  ? 206 LEU B N   1 
ATOM   4437  C CA  . LEU B 2 190 ? 173.747 206.604 162.101 1.00 68.54  ? 206 LEU B CA  1 
ATOM   4438  C C   . LEU B 2 190 ? 173.314 206.646 160.642 1.00 70.21  ? 206 LEU B C   1 
ATOM   4439  O O   . LEU B 2 190 ? 172.722 205.688 160.128 1.00 69.76  ? 206 LEU B O   1 
ATOM   4440  C CB  . LEU B 2 190 ? 172.676 207.224 163.000 1.00 66.85  ? 206 LEU B CB  1 
ATOM   4441  C CG  . LEU B 2 190 ? 172.877 207.205 164.520 1.00 63.75  ? 206 LEU B CG  1 
ATOM   4442  C CD1 . LEU B 2 190 ? 171.723 207.898 165.210 1.00 64.97  ? 206 LEU B CD1 1 
ATOM   4443  C CD2 . LEU B 2 190 ? 173.016 205.803 165.052 1.00 58.24  ? 206 LEU B CD2 1 
ATOM   4444  N N   . LEU B 2 191 ? 173.631 207.739 159.948 1.00 71.85  ? 207 LEU B N   1 
ATOM   4445  C CA  . LEU B 2 191 ? 173.269 207.844 158.541 1.00 69.42  ? 207 LEU B CA  1 
ATOM   4446  C C   . LEU B 2 191 ? 174.125 206.922 157.680 1.00 70.98  ? 207 LEU B C   1 
ATOM   4447  O O   . LEU B 2 191 ? 173.645 206.393 156.673 1.00 74.70  ? 207 LEU B O   1 
ATOM   4448  C CB  . LEU B 2 191 ? 173.379 209.298 158.084 1.00 71.06  ? 207 LEU B CB  1 
ATOM   4449  C CG  . LEU B 2 191 ? 172.353 209.766 157.049 1.00 75.35  ? 207 LEU B CG  1 
ATOM   4450  C CD1 . LEU B 2 191 ? 172.298 211.272 157.027 1.00 77.68  ? 207 LEU B CD1 1 
ATOM   4451  C CD2 . LEU B 2 191 ? 172.681 209.253 155.668 1.00 76.57  ? 207 LEU B CD2 1 
ATOM   4452  N N   . THR B 2 192 ? 175.393 206.708 158.053 1.00 72.30  ? 208 THR B N   1 
ATOM   4453  C CA  . THR B 2 192 ? 176.183 205.705 157.338 1.00 73.06  ? 208 THR B CA  1 
ATOM   4454  C C   . THR B 2 192 ? 175.590 204.315 157.505 1.00 73.10  ? 208 THR B C   1 
ATOM   4455  O O   . THR B 2 192 ? 175.515 203.549 156.539 1.00 75.56  ? 208 THR B O   1 
ATOM   4456  C CB  . THR B 2 192 ? 177.640 205.682 157.801 1.00 75.30  ? 208 THR B CB  1 
ATOM   4457  O OG1 . THR B 2 192 ? 177.773 204.825 158.941 1.00 77.44  ? 208 THR B OG1 1 
ATOM   4458  C CG2 . THR B 2 192 ? 178.117 207.043 158.140 1.00 74.92  ? 208 THR B CG2 1 
ATOM   4459  N N   . ASP B 2 193 ? 175.182 203.958 158.726 1.00 72.38  ? 209 ASP B N   1 
ATOM   4460  C CA  . ASP B 2 193 ? 174.539 202.654 158.895 1.00 69.79  ? 209 ASP B CA  1 
ATOM   4461  C C   . ASP B 2 193 ? 173.242 202.558 158.098 1.00 70.48  ? 209 ASP B C   1 
ATOM   4462  O O   . ASP B 2 193 ? 172.937 201.504 157.530 1.00 72.53  ? 209 ASP B O   1 
ATOM   4463  C CB  . ASP B 2 193 ? 174.296 202.319 160.369 1.00 69.37  ? 209 ASP B CB  1 
ATOM   4464  C CG  . ASP B 2 193 ? 175.551 202.403 161.212 1.00 76.29  ? 209 ASP B CG  1 
ATOM   4465  O OD1 . ASP B 2 193 ? 176.147 203.482 161.324 1.00 76.77  ? 209 ASP B OD1 1 
ATOM   4466  O OD2 . ASP B 2 193 ? 175.957 201.360 161.762 1.00 75.21  ? 209 ASP B OD2 1 
ATOM   4467  N N   . ILE B 2 194 ? 172.467 203.643 158.039 1.00 71.14  ? 210 ILE B N   1 
ATOM   4468  C CA  . ILE B 2 194 ? 171.232 203.623 157.254 1.00 70.15  ? 210 ILE B CA  1 
ATOM   4469  C C   . ILE B 2 194 ? 171.534 203.424 155.771 1.00 73.06  ? 210 ILE B C   1 
ATOM   4470  O O   . ILE B 2 194 ? 170.898 202.605 155.097 1.00 72.36  ? 210 ILE B O   1 
ATOM   4471  C CB  . ILE B 2 194 ? 170.423 204.913 157.492 1.00 66.50  ? 210 ILE B CB  1 
ATOM   4472  C CG1 . ILE B 2 194 ? 169.851 204.943 158.909 1.00 59.90  ? 210 ILE B CG1 1 
ATOM   4473  C CG2 . ILE B 2 194 ? 169.307 205.037 156.471 1.00 65.25  ? 210 ILE B CG2 1 
ATOM   4474  C CD1 . ILE B 2 194 ? 169.380 206.314 159.340 1.00 57.36  ? 210 ILE B CD1 1 
ATOM   4475  N N   . ILE B 2 195 ? 172.502 204.171 155.239 1.00 76.31  ? 211 ILE B N   1 
ATOM   4476  C CA  . ILE B 2 195 ? 172.759 204.170 153.800 1.00 75.88  ? 211 ILE B CA  1 
ATOM   4477  C C   . ILE B 2 195 ? 173.434 202.875 153.359 1.00 80.46  ? 211 ILE B C   1 
ATOM   4478  O O   . ILE B 2 195 ? 173.086 202.302 152.319 1.00 82.63  ? 211 ILE B O   1 
ATOM   4479  C CB  . ILE B 2 195 ? 173.597 205.404 153.420 1.00 74.52  ? 211 ILE B CB  1 
ATOM   4480  C CG1 . ILE B 2 195 ? 172.709 206.644 153.324 1.00 71.98  ? 211 ILE B CG1 1 
ATOM   4481  C CG2 . ILE B 2 195 ? 174.349 205.174 152.126 1.00 85.64  ? 211 ILE B CG2 1 
ATOM   4482  C CD1 . ILE B 2 195 ? 171.484 206.456 152.470 1.00 76.92  ? 211 ILE B CD1 1 
ATOM   4483  N N   . SER B 2 196 ? 174.400 202.390 154.143 1.00 80.85  ? 212 SER B N   1 
ATOM   4484  C CA  . SER B 2 196 ? 175.295 201.334 153.675 1.00 79.61  ? 212 SER B CA  1 
ATOM   4485  C C   . SER B 2 196 ? 174.550 200.035 153.394 1.00 82.44  ? 212 SER B C   1 
ATOM   4486  O O   . SER B 2 196 ? 174.927 199.282 152.489 1.00 86.50  ? 212 SER B O   1 
ATOM   4487  C CB  . SER B 2 196 ? 176.401 201.102 154.703 1.00 78.00  ? 212 SER B CB  1 
ATOM   4488  O OG  . SER B 2 196 ? 177.121 202.296 154.953 1.00 79.56  ? 212 SER B OG  1 
ATOM   4489  N N   . ASP B 2 197 ? 173.499 199.745 154.166 1.00 81.77  ? 213 ASP B N   1 
ATOM   4490  C CA  . ASP B 2 197 ? 172.801 198.472 154.009 1.00 84.65  ? 213 ASP B CA  1 
ATOM   4491  C C   . ASP B 2 197 ? 172.176 198.330 152.627 1.00 86.72  ? 213 ASP B C   1 
ATOM   4492  O O   . ASP B 2 197 ? 172.003 197.208 152.138 1.00 88.72  ? 213 ASP B O   1 
ATOM   4493  C CB  . ASP B 2 197 ? 171.728 198.318 155.086 1.00 78.71  ? 213 ASP B CB  1 
ATOM   4494  C CG  . ASP B 2 197 ? 170.896 199.569 155.259 1.00 79.54  ? 213 ASP B CG  1 
ATOM   4495  O OD1 . ASP B 2 197 ? 170.248 199.994 154.282 1.00 81.49  ? 213 ASP B OD1 1 
ATOM   4496  O OD2 . ASP B 2 197 ? 170.873 200.118 156.377 1.00 74.32  ? 213 ASP B OD2 1 
ATOM   4497  N N   . GLY B 2 198 ? 171.835 199.442 151.984 1.00 85.87  ? 214 GLY B N   1 
ATOM   4498  C CA  . GLY B 2 198 ? 171.224 199.394 150.672 1.00 85.88  ? 214 GLY B CA  1 
ATOM   4499  C C   . GLY B 2 198 ? 169.796 199.895 150.655 1.00 83.02  ? 214 GLY B C   1 
ATOM   4500  O O   . GLY B 2 198 ? 168.872 199.183 151.055 1.00 81.09  ? 214 GLY B O   1 
ATOM   4501  N N   . VAL B 2 199 ? 169.610 201.125 150.189 1.00 80.76  ? 215 VAL B N   1 
ATOM   4502  C CA  . VAL B 2 199 ? 168.297 201.762 150.139 1.00 78.41  ? 215 VAL B CA  1 
ATOM   4503  C C   . VAL B 2 199 ? 167.630 201.453 148.805 1.00 85.48  ? 215 VAL B C   1 
ATOM   4504  O O   . VAL B 2 199 ? 168.278 201.556 147.753 1.00 87.38  ? 215 VAL B O   1 
ATOM   4505  C CB  . VAL B 2 199 ? 168.413 203.278 150.357 1.00 76.59  ? 215 VAL B CB  1 
ATOM   4506  C CG1 . VAL B 2 199 ? 167.092 203.847 150.834 1.00 75.79  ? 215 VAL B CG1 1 
ATOM   4507  C CG2 . VAL B 2 199 ? 169.515 203.580 151.352 1.00 78.85  ? 215 VAL B CG2 1 
ATOM   4508  N N   . PRO B 2 200 ? 166.356 201.060 148.795 1.00 86.85  ? 216 PRO B N   1 
ATOM   4509  C CA  . PRO B 2 200 ? 165.648 200.896 147.521 1.00 88.48  ? 216 PRO B CA  1 
ATOM   4510  C C   . PRO B 2 200 ? 165.586 202.207 146.751 1.00 86.22  ? 216 PRO B C   1 
ATOM   4511  O O   . PRO B 2 200 ? 165.509 203.293 147.330 1.00 84.27  ? 216 PRO B O   1 
ATOM   4512  C CB  . PRO B 2 200 ? 164.250 200.426 147.945 1.00 88.77  ? 216 PRO B CB  1 
ATOM   4513  C CG  . PRO B 2 200 ? 164.145 200.764 149.404 1.00 78.40  ? 216 PRO B CG  1 
ATOM   4514  C CD  . PRO B 2 200 ? 165.531 200.649 149.942 1.00 77.84  ? 216 PRO B CD  1 
ATOM   4515  N N   . CYS B 2 201 ? 165.623 202.091 145.420 1.00 88.08  ? 217 CYS B N   1 
ATOM   4516  C CA  . CYS B 2 201 ? 165.696 203.277 144.572 1.00 90.25  ? 217 CYS B CA  1 
ATOM   4517  C C   . CYS B 2 201 ? 164.428 204.117 144.649 1.00 88.29  ? 217 CYS B C   1 
ATOM   4518  O O   . CYS B 2 201 ? 164.469 205.324 144.389 1.00 86.78  ? 217 CYS B O   1 
ATOM   4519  C CB  . CYS B 2 201 ? 165.972 202.869 143.125 1.00 91.93  ? 217 CYS B CB  1 
ATOM   4520  S SG  . CYS B 2 201 ? 167.334 201.699 142.926 1.00 105.62 ? 217 CYS B SG  1 
ATOM   4521  N N   . SER B 2 202 ? 163.295 203.505 144.999 1.00 85.51  ? 218 SER B N   1 
ATOM   4522  C CA  . SER B 2 202 ? 162.036 204.237 145.049 1.00 82.63  ? 218 SER B CA  1 
ATOM   4523  C C   . SER B 2 202 ? 161.981 205.253 146.181 1.00 82.83  ? 218 SER B C   1 
ATOM   4524  O O   . SER B 2 202 ? 161.090 206.109 146.175 1.00 77.33  ? 218 SER B O   1 
ATOM   4525  C CB  . SER B 2 202 ? 160.866 203.260 145.179 1.00 80.05  ? 218 SER B CB  1 
ATOM   4526  O OG  . SER B 2 202 ? 160.936 202.536 146.395 1.00 80.20  ? 218 SER B OG  1 
ATOM   4527  N N   . GLN B 2 203 ? 162.899 205.184 147.141 1.00 85.43  ? 219 GLN B N   1 
ATOM   4528  C CA  . GLN B 2 203 ? 162.904 206.087 148.284 1.00 81.38  ? 219 GLN B CA  1 
ATOM   4529  C C   . GLN B 2 203 ? 163.732 207.343 148.051 1.00 85.24  ? 219 GLN B C   1 
ATOM   4530  O O   . GLN B 2 203 ? 163.745 208.223 148.919 1.00 83.57  ? 219 GLN B O   1 
ATOM   4531  C CB  . GLN B 2 203 ? 163.422 205.357 149.528 1.00 74.80  ? 219 GLN B CB  1 
ATOM   4532  C CG  . GLN B 2 203 ? 162.639 204.107 149.891 1.00 70.72  ? 219 GLN B CG  1 
ATOM   4533  C CD  . GLN B 2 203 ? 161.147 204.353 149.986 1.00 70.62  ? 219 GLN B CD  1 
ATOM   4534  O OE1 . GLN B 2 203 ? 160.705 205.380 150.499 1.00 71.35  ? 219 GLN B OE1 1 
ATOM   4535  N NE2 . GLN B 2 203 ? 160.360 203.405 149.494 1.00 69.78  ? 219 GLN B NE2 1 
ATOM   4536  N N   . ASN B 2 204 ? 164.412 207.448 146.908 1.00 89.91  ? 220 ASN B N   1 
ATOM   4537  C CA  . ASN B 2 204 ? 165.269 208.579 146.565 1.00 90.15  ? 220 ASN B CA  1 
ATOM   4538  C C   . ASN B 2 204 ? 166.326 208.812 147.639 1.00 89.44  ? 220 ASN B C   1 
ATOM   4539  O O   . ASN B 2 204 ? 166.274 209.826 148.346 1.00 88.33  ? 220 ASN B O   1 
ATOM   4540  C CB  . ASN B 2 204 ? 164.437 209.849 146.362 1.00 88.41  ? 220 ASN B CB  1 
ATOM   4541  C CG  . ASN B 2 204 ? 163.298 209.650 145.383 1.00 87.87  ? 220 ASN B CG  1 
ATOM   4542  O OD1 . ASN B 2 204 ? 163.328 208.741 144.553 1.00 89.74  ? 220 ASN B OD1 1 
ATOM   4543  N ND2 . ASN B 2 204 ? 162.284 210.501 145.475 1.00 86.74  ? 220 ASN B ND2 1 
ATOM   4544  N N   . PRO B 2 205 ? 167.286 207.898 147.805 1.00 88.44  ? 221 PRO B N   1 
ATOM   4545  C CA  . PRO B 2 205 ? 168.344 208.131 148.801 1.00 89.37  ? 221 PRO B CA  1 
ATOM   4546  C C   . PRO B 2 205 ? 169.187 209.359 148.505 1.00 93.53  ? 221 PRO B C   1 
ATOM   4547  O O   . PRO B 2 205 ? 169.639 210.034 149.441 1.00 94.49  ? 221 PRO B O   1 
ATOM   4548  C CB  . PRO B 2 205 ? 169.175 206.843 148.737 1.00 85.84  ? 221 PRO B CB  1 
ATOM   4549  C CG  . PRO B 2 205 ? 168.914 206.288 147.384 1.00 86.88  ? 221 PRO B CG  1 
ATOM   4550  C CD  . PRO B 2 205 ? 167.504 206.658 147.040 1.00 87.23  ? 221 PRO B CD  1 
ATOM   4551  N N   . THR B 2 206 ? 169.407 209.668 147.225 1.00 94.49  ? 222 THR B N   1 
ATOM   4552  C CA  . THR B 2 206 ? 170.226 210.821 146.866 1.00 94.83  ? 222 THR B CA  1 
ATOM   4553  C C   . THR B 2 206 ? 169.601 212.119 147.358 1.00 94.47  ? 222 THR B C   1 
ATOM   4554  O O   . THR B 2 206 ? 170.300 212.986 147.895 1.00 95.68  ? 222 THR B O   1 
ATOM   4555  C CB  . THR B 2 206 ? 170.429 210.869 145.353 1.00 95.87  ? 222 THR B CB  1 
ATOM   4556  O OG1 . THR B 2 206 ? 169.153 210.888 144.702 1.00 94.27  ? 222 THR B OG1 1 
ATOM   4557  C CG2 . THR B 2 206 ? 171.213 209.657 144.885 1.00 95.97  ? 222 THR B CG2 1 
ATOM   4558  N N   . GLU B 2 207 ? 168.286 212.269 147.187 1.00 92.36  ? 223 GLU B N   1 
ATOM   4559  C CA  . GLU B 2 207 ? 167.614 213.473 147.661 1.00 93.65  ? 223 GLU B CA  1 
ATOM   4560  C C   . GLU B 2 207 ? 167.726 213.596 149.175 1.00 93.74  ? 223 GLU B C   1 
ATOM   4561  O O   . GLU B 2 207 ? 167.920 214.696 149.705 1.00 93.03  ? 223 GLU B O   1 
ATOM   4562  C CB  . GLU B 2 207 ? 166.148 213.458 147.226 1.00 96.64  ? 223 GLU B CB  1 
ATOM   4563  C CG  . GLU B 2 207 ? 165.401 214.769 147.432 1.00 100.57 ? 223 GLU B CG  1 
ATOM   4564  C CD  . GLU B 2 207 ? 166.286 215.989 147.269 1.00 103.01 ? 223 GLU B CD  1 
ATOM   4565  O OE1 . GLU B 2 207 ? 166.616 216.332 146.114 1.00 103.51 ? 223 GLU B OE1 1 
ATOM   4566  O OE2 . GLU B 2 207 ? 166.633 216.621 148.288 1.00 99.53  ? 223 GLU B OE2 1 
ATOM   4567  N N   . ALA B 2 208 ? 167.612 212.473 149.888 1.00 92.85  ? 224 ALA B N   1 
ATOM   4568  C CA  . ALA B 2 208 ? 167.777 212.494 151.337 1.00 91.82  ? 224 ALA B CA  1 
ATOM   4569  C C   . ALA B 2 208 ? 169.178 212.944 151.725 1.00 90.89  ? 224 ALA B C   1 
ATOM   4570  O O   . ALA B 2 208 ? 169.348 213.745 152.653 1.00 90.28  ? 224 ALA B O   1 
ATOM   4571  C CB  . ALA B 2 208 ? 167.481 211.111 151.917 1.00 87.17  ? 224 ALA B CB  1 
ATOM   4572  N N   . ILE B 2 209 ? 170.195 212.439 151.022 1.00 90.36  ? 225 ILE B N   1 
ATOM   4573  C CA  . ILE B 2 209 ? 171.570 212.827 151.322 1.00 91.31  ? 225 ILE B CA  1 
ATOM   4574  C C   . ILE B 2 209 ? 171.769 214.320 151.088 1.00 94.73  ? 225 ILE B C   1 
ATOM   4575  O O   . ILE B 2 209 ? 172.368 215.015 151.919 1.00 94.76  ? 225 ILE B O   1 
ATOM   4576  C CB  . ILE B 2 209 ? 172.556 211.983 150.495 1.00 88.00  ? 225 ILE B CB  1 
ATOM   4577  C CG1 . ILE B 2 209 ? 172.500 210.521 150.936 1.00 89.14  ? 225 ILE B CG1 1 
ATOM   4578  C CG2 . ILE B 2 209 ? 173.970 212.518 150.634 1.00 87.95  ? 225 ILE B CG2 1 
ATOM   4579  C CD1 . ILE B 2 209 ? 172.950 209.548 149.877 1.00 88.75  ? 225 ILE B CD1 1 
ATOM   4580  N N   . GLU B 2 210 ? 171.270 214.841 149.961 1.00 97.49  ? 226 GLU B N   1 
ATOM   4581  C CA  . GLU B 2 210 ? 171.419 216.273 149.702 1.00 96.01  ? 226 GLU B CA  1 
ATOM   4582  C C   . GLU B 2 210 ? 170.673 217.110 150.732 1.00 97.64  ? 226 GLU B C   1 
ATOM   4583  O O   . GLU B 2 210 ? 171.180 218.145 151.175 1.00 100.51 ? 226 GLU B O   1 
ATOM   4584  C CB  . GLU B 2 210 ? 170.963 216.646 148.289 1.00 97.18  ? 226 GLU B CB  1 
ATOM   4585  C CG  . GLU B 2 210 ? 171.303 215.647 147.210 1.00 99.69  ? 226 GLU B CG  1 
ATOM   4586  C CD  . GLU B 2 210 ? 172.636 215.932 146.552 1.00 102.78 ? 226 GLU B CD  1 
ATOM   4587  O OE1 . GLU B 2 210 ? 173.650 216.014 147.276 1.00 98.60  ? 226 GLU B OE1 1 
ATOM   4588  O OE2 . GLU B 2 210 ? 172.672 216.072 145.311 1.00 105.71 ? 226 GLU B OE2 1 
ATOM   4589  N N   . ALA B 2 211 ? 169.468 216.691 151.124 1.00 97.71  ? 227 ALA B N   1 
ATOM   4590  C CA  . ALA B 2 211 ? 168.725 217.449 152.127 1.00 96.26  ? 227 ALA B CA  1 
ATOM   4591  C C   . ALA B 2 211 ? 169.465 217.475 153.459 1.00 96.94  ? 227 ALA B C   1 
ATOM   4592  O O   . ALA B 2 211 ? 169.595 218.535 154.089 1.00 99.02  ? 227 ALA B O   1 
ATOM   4593  C CB  . ALA B 2 211 ? 167.326 216.860 152.300 1.00 93.70  ? 227 ALA B CB  1 
ATOM   4594  N N   . TRP B 2 212 ? 169.976 216.321 153.894 1.00 95.63  ? 228 TRP B N   1 
ATOM   4595  C CA  . TRP B 2 212 ? 170.706 216.270 155.155 1.00 95.49  ? 228 TRP B CA  1 
ATOM   4596  C C   . TRP B 2 212 ? 171.974 217.113 155.094 1.00 98.26  ? 228 TRP B C   1 
ATOM   4597  O O   . TRP B 2 212 ? 172.297 217.830 156.048 1.00 99.66  ? 228 TRP B O   1 
ATOM   4598  C CB  . TRP B 2 212 ? 171.039 214.823 155.513 1.00 92.10  ? 228 TRP B CB  1 
ATOM   4599  C CG  . TRP B 2 212 ? 171.746 214.685 156.823 1.00 92.20  ? 228 TRP B CG  1 
ATOM   4600  C CD1 . TRP B 2 212 ? 171.184 214.746 158.064 1.00 89.13  ? 228 TRP B CD1 1 
ATOM   4601  C CD2 . TRP B 2 212 ? 173.148 214.471 157.027 1.00 94.23  ? 228 TRP B CD2 1 
ATOM   4602  N NE1 . TRP B 2 212 ? 172.147 214.578 159.027 1.00 88.51  ? 228 TRP B NE1 1 
ATOM   4603  C CE2 . TRP B 2 212 ? 173.361 214.406 158.417 1.00 92.50  ? 228 TRP B CE2 1 
ATOM   4604  C CE3 . TRP B 2 212 ? 174.240 214.319 156.169 1.00 95.38  ? 228 TRP B CE3 1 
ATOM   4605  C CZ2 . TRP B 2 212 ? 174.623 214.202 158.969 1.00 91.26  ? 228 TRP B CZ2 1 
ATOM   4606  C CZ3 . TRP B 2 212 ? 175.492 214.115 156.720 1.00 94.53  ? 228 TRP B CZ3 1 
ATOM   4607  C CH2 . TRP B 2 212 ? 175.673 214.058 158.106 1.00 91.44  ? 228 TRP B CH2 1 
ATOM   4608  N N   . ILE B 2 213 ? 172.705 217.048 153.977 1.00 98.89  ? 229 ILE B N   1 
ATOM   4609  C CA  . ILE B 2 213 ? 173.948 217.801 153.868 1.00 100.09 ? 229 ILE B CA  1 
ATOM   4610  C C   . ILE B 2 213 ? 173.697 219.290 153.665 1.00 100.93 ? 229 ILE B C   1 
ATOM   4611  O O   . ILE B 2 213 ? 174.587 220.104 153.935 1.00 103.58 ? 229 ILE B O   1 
ATOM   4612  C CB  . ILE B 2 213 ? 174.822 217.228 152.736 1.00 99.87  ? 229 ILE B CB  1 
ATOM   4613  C CG1 . ILE B 2 213 ? 176.302 217.423 153.058 1.00 103.08 ? 229 ILE B CG1 1 
ATOM   4614  C CG2 . ILE B 2 213 ? 174.481 217.872 151.405 1.00 101.83 ? 229 ILE B CG2 1 
ATOM   4615  C CD1 . ILE B 2 213 ? 177.224 216.783 152.055 1.00 106.35 ? 229 ILE B CD1 1 
ATOM   4616  N N   . ASN B 2 214 ? 172.511 219.672 153.194 1.00 100.90 ? 230 ASN B N   1 
ATOM   4617  C CA  . ASN B 2 214 ? 172.159 221.074 153.040 1.00 102.38 ? 230 ASN B CA  1 
ATOM   4618  C C   . ASN B 2 214 ? 171.459 221.646 154.262 1.00 103.97 ? 230 ASN B C   1 
ATOM   4619  O O   . ASN B 2 214 ? 171.226 222.859 154.308 1.00 106.30 ? 230 ASN B O   1 
ATOM   4620  C CB  . ASN B 2 214 ? 171.266 221.266 151.809 1.00 103.21 ? 230 ASN B CB  1 
ATOM   4621  C CG  . ASN B 2 214 ? 172.002 221.015 150.508 1.00 105.54 ? 230 ASN B CG  1 
ATOM   4622  O OD1 . ASN B 2 214 ? 173.228 220.916 150.486 1.00 104.87 ? 230 ASN B OD1 1 
ATOM   4623  N ND2 . ASN B 2 214 ? 171.255 220.907 149.416 1.00 102.26 ? 230 ASN B ND2 1 
ATOM   4624  N N   . PHE B 2 215 ? 171.108 220.810 155.242 1.00 104.38 ? 231 PHE B N   1 
ATOM   4625  C CA  . PHE B 2 215 ? 170.552 221.340 156.483 1.00 106.81 ? 231 PHE B CA  1 
ATOM   4626  C C   . PHE B 2 215 ? 171.540 222.273 157.173 1.00 108.29 ? 231 PHE B C   1 
ATOM   4627  O O   . PHE B 2 215 ? 171.158 223.338 157.670 1.00 106.22 ? 231 PHE B O   1 
ATOM   4628  C CB  . PHE B 2 215 ? 170.154 220.199 157.416 1.00 101.25 ? 231 PHE B CB  1 
ATOM   4629  C CG  . PHE B 2 215 ? 169.655 220.661 158.755 1.00 100.34 ? 231 PHE B CG  1 
ATOM   4630  C CD1 . PHE B 2 215 ? 168.431 221.298 158.870 1.00 98.63  ? 231 PHE B CD1 1 
ATOM   4631  C CD2 . PHE B 2 215 ? 170.412 220.463 159.897 1.00 101.56 ? 231 PHE B CD2 1 
ATOM   4632  C CE1 . PHE B 2 215 ? 167.970 221.726 160.100 1.00 99.84  ? 231 PHE B CE1 1 
ATOM   4633  C CE2 . PHE B 2 215 ? 169.956 220.890 161.129 1.00 100.34 ? 231 PHE B CE2 1 
ATOM   4634  C CZ  . PHE B 2 215 ? 168.733 221.521 161.231 1.00 99.93  ? 231 PHE B CZ  1 
ATOM   4635  N N   . ASN B 2 216 ? 172.815 221.889 157.214 1.00 110.58 ? 232 ASN B N   1 
ATOM   4636  C CA  . ASN B 2 216 ? 173.861 222.735 157.785 1.00 116.06 ? 232 ASN B CA  1 
ATOM   4637  C C   . ASN B 2 216 ? 175.127 222.501 156.975 1.00 117.62 ? 232 ASN B C   1 
ATOM   4638  O O   . ASN B 2 216 ? 175.805 221.488 157.167 1.00 115.37 ? 232 ASN B O   1 
ATOM   4639  C CB  . ASN B 2 216 ? 174.084 222.418 159.262 1.00 115.99 ? 232 ASN B CB  1 
ATOM   4640  C CG  . ASN B 2 216 ? 175.278 223.153 159.845 1.00 121.51 ? 232 ASN B CG  1 
ATOM   4641  O OD1 . ASN B 2 216 ? 175.667 224.215 159.361 1.00 121.28 ? 232 ASN B OD1 1 
ATOM   4642  N ND2 . ASN B 2 216 ? 175.865 222.586 160.892 1.00 121.62 ? 232 ASN B ND2 1 
ATOM   4643  N N   . LYS B 2 217 ? 175.449 223.434 156.082 1.00 117.83 ? 233 LYS B N   1 
ATOM   4644  C CA  . LYS B 2 217 ? 176.568 223.283 155.162 1.00 119.76 ? 233 LYS B CA  1 
ATOM   4645  C C   . LYS B 2 217 ? 177.883 223.805 155.722 1.00 123.01 ? 233 LYS B C   1 
ATOM   4646  O O   . LYS B 2 217 ? 178.900 223.751 155.024 1.00 123.18 ? 233 LYS B O   1 
ATOM   4647  C CB  . LYS B 2 217 ? 176.260 223.992 153.839 1.00 118.23 ? 233 LYS B CB  1 
ATOM   4648  C CG  . LYS B 2 217 ? 176.486 223.131 152.610 1.00 118.43 ? 233 LYS B CG  1 
ATOM   4649  C CD  . LYS B 2 217 ? 176.022 223.835 151.346 1.00 116.73 ? 233 LYS B CD  1 
ATOM   4650  C CE  . LYS B 2 217 ? 175.974 222.876 150.168 1.00 114.34 ? 233 LYS B CE  1 
ATOM   4651  N NZ  . LYS B 2 217 ? 175.384 223.510 148.957 1.00 113.27 ? 233 LYS B NZ  1 
ATOM   4652  N N   . GLU B 2 218 ? 177.893 224.307 156.959 1.00 123.37 ? 234 GLU B N   1 
ATOM   4653  C CA  . GLU B 2 218 ? 179.122 224.866 157.513 1.00 124.30 ? 234 GLU B CA  1 
ATOM   4654  C C   . GLU B 2 218 ? 180.134 223.776 157.845 1.00 126.01 ? 234 GLU B C   1 
ATOM   4655  O O   . GLU B 2 218 ? 181.324 223.916 157.539 1.00 125.25 ? 234 GLU B O   1 
ATOM   4656  C CB  . GLU B 2 218 ? 178.805 225.701 158.754 1.00 125.68 ? 234 GLU B CB  1 
ATOM   4657  C CG  . GLU B 2 218 ? 178.648 227.187 158.475 1.00 126.22 ? 234 GLU B CG  1 
ATOM   4658  C CD  . GLU B 2 218 ? 178.005 227.932 159.629 1.00 126.88 ? 234 GLU B CD  1 
ATOM   4659  O OE1 . GLU B 2 218 ? 177.750 227.302 160.676 1.00 126.46 ? 234 GLU B OE1 1 
ATOM   4660  O OE2 . GLU B 2 218 ? 177.757 229.148 159.488 1.00 125.79 ? 234 GLU B OE2 1 
ATOM   4661  N N   . GLU B 2 219 ? 179.687 222.687 158.467 1.00 125.28 ? 235 GLU B N   1 
ATOM   4662  C CA  . GLU B 2 219 ? 180.572 221.616 158.913 1.00 125.49 ? 235 GLU B CA  1 
ATOM   4663  C C   . GLU B 2 219 ? 180.010 220.252 158.536 1.00 123.84 ? 235 GLU B C   1 
ATOM   4664  O O   . GLU B 2 219 ? 180.084 219.293 159.310 1.00 121.68 ? 235 GLU B O   1 
ATOM   4665  C CB  . GLU B 2 219 ? 180.813 221.698 160.419 1.00 125.29 ? 235 GLU B CB  1 
ATOM   4666  C CG  . GLU B 2 219 ? 181.534 222.958 160.867 1.00 128.93 ? 235 GLU B CG  1 
ATOM   4667  C CD  . GLU B 2 219 ? 180.581 224.043 161.329 1.00 130.11 ? 235 GLU B CD  1 
ATOM   4668  O OE1 . GLU B 2 219 ? 179.366 223.769 161.424 1.00 130.15 ? 235 GLU B OE1 1 
ATOM   4669  O OE2 . GLU B 2 219 ? 181.047 225.171 161.596 1.00 127.25 ? 235 GLU B OE2 1 
ATOM   4670  N N   . ARG B 2 220 ? 179.433 220.144 157.340 1.00 120.76 ? 236 ARG B N   1 
ATOM   4671  C CA  . ARG B 2 220 ? 178.904 218.869 156.872 1.00 114.00 ? 236 ARG B CA  1 
ATOM   4672  C C   . ARG B 2 220 ? 179.249 218.547 155.426 1.00 114.05 ? 236 ARG B C   1 
ATOM   4673  O O   . ARG B 2 220 ? 179.083 217.391 155.024 1.00 113.17 ? 236 ARG B O   1 
ATOM   4674  C CB  . ARG B 2 220 ? 177.378 218.836 157.041 1.00 110.13 ? 236 ARG B CB  1 
ATOM   4675  C CG  . ARG B 2 220 ? 176.782 217.447 157.189 1.00 102.82 ? 236 ARG B CG  1 
ATOM   4676  C CD  . ARG B 2 220 ? 175.297 217.514 157.520 1.00 99.94  ? 236 ARG B CD  1 
ATOM   4677  N NE  . ARG B 2 220 ? 175.056 217.646 158.952 1.00 100.70 ? 236 ARG B NE  1 
ATOM   4678  C CZ  . ARG B 2 220 ? 173.853 217.712 159.505 1.00 98.13  ? 236 ARG B CZ  1 
ATOM   4679  N NH1 . ARG B 2 220 ? 172.752 217.657 158.775 1.00 96.50  ? 236 ARG B NH1 1 
ATOM   4680  N NH2 . ARG B 2 220 ? 173.752 217.836 160.826 1.00 97.07  ? 236 ARG B NH2 1 
ATOM   4681  N N   . GLU B 2 221 ? 179.728 219.508 154.632 1.00 114.67 ? 237 GLU B N   1 
ATOM   4682  C CA  . GLU B 2 221 ? 180.003 219.234 153.225 1.00 114.13 ? 237 GLU B CA  1 
ATOM   4683  C C   . GLU B 2 221 ? 181.244 218.372 153.044 1.00 111.71 ? 237 GLU B C   1 
ATOM   4684  O O   . GLU B 2 221 ? 181.398 217.724 152.003 1.00 112.59 ? 237 GLU B O   1 
ATOM   4685  C CB  . GLU B 2 221 ? 180.151 220.542 152.449 1.00 114.99 ? 237 GLU B CB  1 
ATOM   4686  C CG  . GLU B 2 221 ? 178.998 220.829 151.500 1.00 116.25 ? 237 GLU B CG  1 
ATOM   4687  C CD  . GLU B 2 221 ? 179.128 220.106 150.171 1.00 117.67 ? 237 GLU B CD  1 
ATOM   4688  O OE1 . GLU B 2 221 ? 180.064 219.294 150.017 1.00 116.99 ? 237 GLU B OE1 1 
ATOM   4689  O OE2 . GLU B 2 221 ? 178.289 220.349 149.279 1.00 117.54 ? 237 GLU B OE2 1 
ATOM   4690  N N   . ALA B 2 222 ? 182.138 218.347 154.035 1.00 110.58 ? 238 ALA B N   1 
ATOM   4691  C CA  . ALA B 2 222 ? 183.320 217.500 153.941 1.00 112.21 ? 238 ALA B CA  1 
ATOM   4692  C C   . ALA B 2 222 ? 182.968 216.019 153.944 1.00 113.09 ? 238 ALA B C   1 
ATOM   4693  O O   . ALA B 2 222 ? 183.824 215.189 153.621 1.00 112.40 ? 238 ALA B O   1 
ATOM   4694  C CB  . ALA B 2 222 ? 184.285 217.810 155.086 1.00 110.24 ? 238 ALA B CB  1 
ATOM   4695  N N   . PHE B 2 223 ? 181.734 215.674 154.299 1.00 111.09 ? 239 PHE B N   1 
ATOM   4696  C CA  . PHE B 2 223 ? 181.277 214.294 154.365 1.00 108.43 ? 239 PHE B CA  1 
ATOM   4697  C C   . PHE B 2 223 ? 180.636 213.816 153.068 1.00 108.16 ? 239 PHE B C   1 
ATOM   4698  O O   . PHE B 2 223 ? 180.172 212.673 153.011 1.00 107.61 ? 239 PHE B O   1 
ATOM   4699  C CB  . PHE B 2 223 ? 180.275 214.137 155.511 1.00 106.70 ? 239 PHE B CB  1 
ATOM   4700  C CG  . PHE B 2 223 ? 180.875 214.327 156.875 1.00 107.88 ? 239 PHE B CG  1 
ATOM   4701  C CD1 . PHE B 2 223 ? 182.032 213.660 157.242 1.00 106.50 ? 239 PHE B CD1 1 
ATOM   4702  C CD2 . PHE B 2 223 ? 180.272 215.168 157.796 1.00 107.91 ? 239 PHE B CD2 1 
ATOM   4703  C CE1 . PHE B 2 223 ? 182.577 213.832 158.501 1.00 107.41 ? 239 PHE B CE1 1 
ATOM   4704  C CE2 . PHE B 2 223 ? 180.813 215.346 159.054 1.00 107.42 ? 239 PHE B CE2 1 
ATOM   4705  C CZ  . PHE B 2 223 ? 181.967 214.677 159.407 1.00 107.50 ? 239 PHE B CZ  1 
ATOM   4706  N N   . ALA B 2 224 ? 180.592 214.661 152.034 1.00 109.29 ? 240 ALA B N   1 
ATOM   4707  C CA  . ALA B 2 224 ? 179.845 214.328 150.824 1.00 108.27 ? 240 ALA B CA  1 
ATOM   4708  C C   . ALA B 2 224 ? 180.426 213.106 150.122 1.00 107.96 ? 240 ALA B C   1 
ATOM   4709  O O   . ALA B 2 224 ? 179.686 212.215 149.687 1.00 108.51 ? 240 ALA B O   1 
ATOM   4710  C CB  . ALA B 2 224 ? 179.825 215.529 149.878 1.00 105.83 ? 240 ALA B CB  1 
ATOM   4711  N N   . GLU B 2 225 ? 181.753 213.051 149.993 1.00 107.78 ? 241 GLU B N   1 
ATOM   4712  C CA  . GLU B 2 225 ? 182.377 211.972 149.234 1.00 109.48 ? 241 GLU B CA  1 
ATOM   4713  C C   . GLU B 2 225 ? 182.147 210.621 149.899 1.00 109.64 ? 241 GLU B C   1 
ATOM   4714  O O   . GLU B 2 225 ? 181.818 209.636 149.228 1.00 108.84 ? 241 GLU B O   1 
ATOM   4715  C CB  . GLU B 2 225 ? 183.871 212.244 149.065 1.00 109.98 ? 241 GLU B CB  1 
ATOM   4716  C CG  . GLU B 2 225 ? 184.554 211.325 148.066 1.00 111.18 ? 241 GLU B CG  1 
ATOM   4717  C CD  . GLU B 2 225 ? 183.748 211.149 146.794 1.00 114.62 ? 241 GLU B CD  1 
ATOM   4718  O OE1 . GLU B 2 225 ? 183.457 212.164 146.127 1.00 112.50 ? 241 GLU B OE1 1 
ATOM   4719  O OE2 . GLU B 2 225 ? 183.406 209.996 146.460 1.00 114.68 ? 241 GLU B OE2 1 
ATOM   4720  N N   . SER B 2 226 ? 182.316 210.555 151.222 1.00 110.12 ? 242 SER B N   1 
ATOM   4721  C CA  . SER B 2 226 ? 182.117 209.295 151.930 1.00 108.81 ? 242 SER B CA  1 
ATOM   4722  C C   . SER B 2 226 ? 180.664 208.840 151.855 1.00 107.12 ? 242 SER B C   1 
ATOM   4723  O O   . SER B 2 226 ? 180.391 207.647 151.676 1.00 104.56 ? 242 SER B O   1 
ATOM   4724  C CB  . SER B 2 226 ? 182.562 209.436 153.385 1.00 108.04 ? 242 SER B CB  1 
ATOM   4725  O OG  . SER B 2 226 ? 183.884 209.941 153.466 1.00 109.54 ? 242 SER B OG  1 
ATOM   4726  N N   . LEU B 2 227 ? 179.721 209.774 151.997 1.00 106.39 ? 243 LEU B N   1 
ATOM   4727  C CA  . LEU B 2 227 ? 178.308 209.417 151.920 1.00 104.47 ? 243 LEU B CA  1 
ATOM   4728  C C   . LEU B 2 227 ? 177.931 208.925 150.528 1.00 103.73 ? 243 LEU B C   1 
ATOM   4729  O O   . LEU B 2 227 ? 177.196 207.941 150.391 1.00 101.69 ? 243 LEU B O   1 
ATOM   4730  C CB  . LEU B 2 227 ? 177.443 210.612 152.318 1.00 102.01 ? 243 LEU B CB  1 
ATOM   4731  C CG  . LEU B 2 227 ? 177.097 210.729 153.802 1.00 98.83  ? 243 LEU B CG  1 
ATOM   4732  C CD1 . LEU B 2 227 ? 176.208 211.934 154.046 1.00 94.96  ? 243 LEU B CD1 1 
ATOM   4733  C CD2 . LEU B 2 227 ? 176.428 209.458 154.297 1.00 89.34  ? 243 LEU B CD2 1 
ATOM   4734  N N   . ARG B 2 228 ? 178.421 209.597 149.483 1.00 104.82 ? 244 ARG B N   1 
ATOM   4735  C CA  . ARG B 2 228 ? 178.070 209.196 148.125 1.00 104.33 ? 244 ARG B CA  1 
ATOM   4736  C C   . ARG B 2 228 ? 178.732 207.877 147.743 1.00 104.53 ? 244 ARG B C   1 
ATOM   4737  O O   . ARG B 2 228 ? 178.134 207.061 147.031 1.00 104.21 ? 244 ARG B O   1 
ATOM   4738  C CB  . ARG B 2 228 ? 178.454 210.296 147.137 1.00 104.23 ? 244 ARG B CB  1 
ATOM   4739  C CG  . ARG B 2 228 ? 177.567 211.528 147.209 1.00 101.43 ? 244 ARG B CG  1 
ATOM   4740  C CD  . ARG B 2 228 ? 178.092 212.634 146.311 1.00 104.84 ? 244 ARG B CD  1 
ATOM   4741  N NE  . ARG B 2 228 ? 177.662 213.953 146.759 1.00 105.02 ? 244 ARG B NE  1 
ATOM   4742  C CZ  . ARG B 2 228 ? 178.223 215.093 146.377 1.00 103.38 ? 244 ARG B CZ  1 
ATOM   4743  N NH1 . ARG B 2 228 ? 179.245 215.112 145.537 1.00 100.50 ? 244 ARG B NH1 1 
ATOM   4744  N NH2 . ARG B 2 228 ? 177.747 216.241 146.850 1.00 101.47 ? 244 ARG B NH2 1 
ATOM   4745  N N   . THR B 2 229 ? 179.966 207.653 148.199 1.00 104.98 ? 245 THR B N   1 
ATOM   4746  C CA  . THR B 2 229 ? 180.666 206.416 147.865 1.00 105.69 ? 245 THR B CA  1 
ATOM   4747  C C   . THR B 2 229 ? 179.975 205.201 148.473 1.00 103.58 ? 245 THR B C   1 
ATOM   4748  O O   . THR B 2 229 ? 179.882 204.148 147.831 1.00 100.16 ? 245 THR B O   1 
ATOM   4749  C CB  . THR B 2 229 ? 182.119 206.494 148.333 1.00 107.75 ? 245 THR B CB  1 
ATOM   4750  O OG1 . THR B 2 229 ? 182.695 207.732 147.901 1.00 109.97 ? 245 THR B OG1 1 
ATOM   4751  C CG2 . THR B 2 229 ? 182.926 205.339 147.761 1.00 105.23 ? 245 THR B CG2 1 
ATOM   4752  N N   . SER B 2 230 ? 179.483 205.327 149.705 1.00 103.88 ? 246 SER B N   1 
ATOM   4753  C CA  . SER B 2 230 ? 178.853 204.209 150.396 1.00 100.90 ? 246 SER B CA  1 
ATOM   4754  C C   . SER B 2 230 ? 177.404 203.989 149.986 1.00 100.29 ? 246 SER B C   1 
ATOM   4755  O O   . SER B 2 230 ? 176.794 203.015 150.441 1.00 95.47  ? 246 SER B O   1 
ATOM   4756  C CB  . SER B 2 230 ? 178.929 204.420 151.910 1.00 97.90  ? 246 SER B CB  1 
ATOM   4757  O OG  . SER B 2 230 ? 177.738 205.007 152.403 1.00 98.92  ? 246 SER B OG  1 
ATOM   4758  N N   . LEU B 2 231 ? 176.840 204.861 149.153 1.00 101.09 ? 247 LEU B N   1 
ATOM   4759  C CA  . LEU B 2 231 ? 175.459 204.700 148.718 1.00 98.81  ? 247 LEU B CA  1 
ATOM   4760  C C   . LEU B 2 231 ? 175.285 203.396 147.951 1.00 102.86 ? 247 LEU B C   1 
ATOM   4761  O O   . LEU B 2 231 ? 176.102 203.051 147.092 1.00 106.27 ? 247 LEU B O   1 
ATOM   4762  C CB  . LEU B 2 231 ? 175.037 205.883 147.849 1.00 98.15  ? 247 LEU B CB  1 
ATOM   4763  C CG  . LEU B 2 231 ? 173.540 206.000 147.565 1.00 99.48  ? 247 LEU B CG  1 
ATOM   4764  C CD1 . LEU B 2 231 ? 172.736 205.778 148.831 1.00 94.85  ? 247 LEU B CD1 1 
ATOM   4765  C CD2 . LEU B 2 231 ? 173.217 207.350 146.950 1.00 101.85 ? 247 LEU B CD2 1 
ATOM   4766  N N   . LYS B 2 232 ? 174.216 202.671 148.266 1.00 102.00 ? 248 LYS B N   1 
ATOM   4767  C CA  . LYS B 2 232 ? 173.915 201.397 147.629 1.00 103.01 ? 248 LYS B CA  1 
ATOM   4768  C C   . LYS B 2 232 ? 172.477 201.413 147.136 1.00 101.38 ? 248 LYS B C   1 
ATOM   4769  O O   . LYS B 2 232 ? 171.562 201.742 147.896 1.00 101.37 ? 248 LYS B O   1 
ATOM   4770  C CB  . LYS B 2 232 ? 174.131 200.228 148.595 1.00 98.95  ? 248 LYS B CB  1 
ATOM   4771  C CG  . LYS B 2 232 ? 173.660 198.886 148.062 1.00 100.16 ? 248 LYS B CG  1 
ATOM   4772  C CD  . LYS B 2 232 ? 174.630 198.327 147.034 1.00 104.67 ? 248 LYS B CD  1 
ATOM   4773  C CE  . LYS B 2 232 ? 176.023 198.167 147.620 1.00 105.06 ? 248 LYS B CE  1 
ATOM   4774  N NZ  . LYS B 2 232 ? 177.081 198.382 146.596 1.00 103.87 ? 248 LYS B NZ  1 
ATOM   4775  N N   . GLU B 2 233 ? 172.284 201.058 145.871 1.00 102.22 ? 249 GLU B N   1 
ATOM   4776  C CA  . GLU B 2 233 ? 170.962 200.945 145.275 1.00 101.40 ? 249 GLU B CA  1 
ATOM   4777  C C   . GLU B 2 233 ? 170.670 199.484 144.966 1.00 103.75 ? 249 GLU B C   1 
ATOM   4778  O O   . GLU B 2 233 ? 171.545 198.753 144.492 1.00 103.90 ? 249 GLU B O   1 
ATOM   4779  C CB  . GLU B 2 233 ? 170.854 201.782 143.999 1.00 101.32 ? 249 GLU B CB  1 
ATOM   4780  C CG  . GLU B 2 233 ? 170.463 203.231 144.235 1.00 103.44 ? 249 GLU B CG  1 
ATOM   4781  C CD  . GLU B 2 233 ? 171.636 204.181 144.103 1.00 110.36 ? 249 GLU B CD  1 
ATOM   4782  O OE1 . GLU B 2 233 ? 172.583 203.860 143.354 1.00 110.39 ? 249 GLU B OE1 1 
ATOM   4783  O OE2 . GLU B 2 233 ? 171.611 205.252 144.745 1.00 110.02 ? 249 GLU B OE2 1 
ATOM   4784  N N   . ILE B 2 234 ? 169.435 199.061 145.238 1.00 101.45 ? 250 ILE B N   1 
ATOM   4785  C CA  . ILE B 2 234 ? 169.020 197.682 145.038 1.00 100.67 ? 250 ILE B CA  1 
ATOM   4786  C C   . ILE B 2 234 ? 167.738 197.665 144.218 1.00 101.92 ? 250 ILE B C   1 
ATOM   4787  O O   . ILE B 2 234 ? 167.057 198.680 144.060 1.00 98.50  ? 250 ILE B O   1 
ATOM   4788  C CB  . ILE B 2 234 ? 168.817 196.933 146.372 1.00 97.47  ? 250 ILE B CB  1 
ATOM   4789  C CG1 . ILE B 2 234 ? 167.790 197.662 147.240 1.00 95.41  ? 250 ILE B CG1 1 
ATOM   4790  C CG2 . ILE B 2 234 ? 170.142 196.783 147.105 1.00 93.50  ? 250 ILE B CG2 1 
ATOM   4791  C CD1 . ILE B 2 234 ? 167.749 197.181 148.673 1.00 93.01  ? 250 ILE B CD1 1 
ATOM   4792  N N   . GLY B 2 235 ? 167.416 196.486 143.692 1.00 102.00 ? 251 GLY B N   1 
ATOM   4793  C CA  . GLY B 2 235 ? 166.230 196.323 142.877 1.00 98.20  ? 251 GLY B CA  1 
ATOM   4794  C C   . GLY B 2 235 ? 164.958 196.211 143.692 1.00 98.90  ? 251 GLY B C   1 
ATOM   4795  O O   . GLY B 2 235 ? 164.795 196.908 144.698 1.00 100.80 ? 251 GLY B O   1 
ATOM   4796  N N   . GLU B 2 236 ? 164.049 195.337 143.270 1.00 98.47  ? 252 GLU B N   1 
ATOM   4797  C CA  . GLU B 2 236 ? 162.763 195.148 143.937 1.00 98.61  ? 252 GLU B CA  1 
ATOM   4798  C C   . GLU B 2 236 ? 162.856 193.896 144.804 1.00 96.71  ? 252 GLU B C   1 
ATOM   4799  O O   . GLU B 2 236 ? 162.752 192.772 144.307 1.00 91.29  ? 252 GLU B O   1 
ATOM   4800  C CB  . GLU B 2 236 ? 161.639 195.048 142.912 1.00 94.83  ? 252 GLU B CB  1 
ATOM   4801  C CG  . GLU B 2 236 ? 161.654 196.171 141.887 1.00 93.59  ? 252 GLU B CG  1 
ATOM   4802  C CD  . GLU B 2 236 ? 160.645 197.260 142.195 1.00 94.05  ? 252 GLU B CD  1 
ATOM   4803  O OE1 . GLU B 2 236 ? 159.431 197.009 142.046 1.00 90.17  ? 252 GLU B OE1 1 
ATOM   4804  O OE2 . GLU B 2 236 ? 161.067 198.368 142.587 1.00 94.33  ? 252 GLU B OE2 1 
ATOM   4805  N N   . ASN B 2 237 ? 163.048 194.098 146.109 1.00 97.34  ? 253 ASN B N   1 
ATOM   4806  C CA  . ASN B 2 237 ? 163.264 193.005 147.046 1.00 95.80  ? 253 ASN B CA  1 
ATOM   4807  C C   . ASN B 2 237 ? 161.975 192.432 147.619 1.00 93.82  ? 253 ASN B C   1 
ATOM   4808  O O   . ASN B 2 237 ? 162.026 191.408 148.309 1.00 96.82  ? 253 ASN B O   1 
ATOM   4809  C CB  . ASN B 2 237 ? 164.162 193.469 148.199 1.00 99.93  ? 253 ASN B CB  1 
ATOM   4810  C CG  . ASN B 2 237 ? 163.807 194.858 148.692 1.00 101.81 ? 253 ASN B CG  1 
ATOM   4811  O OD1 . ASN B 2 237 ? 162.634 195.186 148.869 1.00 101.23 ? 253 ASN B OD1 1 
ATOM   4812  N ND2 . ASN B 2 237 ? 164.821 195.682 148.920 1.00 99.90  ? 253 ASN B ND2 1 
ATOM   4813  N N   . VAL B 2 238 ? 160.831 193.056 147.357 1.00 89.08  ? 254 VAL B N   1 
ATOM   4814  C CA  . VAL B 2 238 ? 159.541 192.573 147.838 1.00 87.26  ? 254 VAL B CA  1 
ATOM   4815  C C   . VAL B 2 238 ? 158.843 191.847 146.695 1.00 79.51  ? 254 VAL B C   1 
ATOM   4816  O O   . VAL B 2 238 ? 158.839 192.325 145.553 1.00 78.68  ? 254 VAL B O   1 
ATOM   4817  C CB  . VAL B 2 238 ? 158.682 193.727 148.385 1.00 84.27  ? 254 VAL B CB  1 
ATOM   4818  C CG1 . VAL B 2 238 ? 158.470 194.795 147.325 1.00 78.34  ? 254 VAL B CG1 1 
ATOM   4819  C CG2 . VAL B 2 238 ? 157.355 193.198 148.898 1.00 84.01  ? 254 VAL B CG2 1 
ATOM   4820  N N   . HIS B 2 239 ? 158.280 190.677 146.990 1.00 62.42  ? 255 HIS B N   1 
ATOM   4821  C CA  . HIS B 2 239 ? 157.735 189.836 145.938 1.00 55.24  ? 255 HIS B CA  1 
ATOM   4822  C C   . HIS B 2 239 ? 156.762 188.824 146.523 1.00 50.31  ? 255 HIS B C   1 
ATOM   4823  O O   . HIS B 2 239 ? 156.958 188.316 147.630 1.00 47.67  ? 255 HIS B O   1 
ATOM   4824  C CB  . HIS B 2 239 ? 158.853 189.108 145.183 1.00 51.56  ? 255 HIS B CB  1 
ATOM   4825  C CG  . HIS B 2 239 ? 158.904 189.418 143.721 1.00 47.91  ? 255 HIS B CG  1 
ATOM   4826  N ND1 . HIS B 2 239 ? 159.625 190.475 143.210 1.00 51.52  ? 255 HIS B ND1 1 
ATOM   4827  C CD2 . HIS B 2 239 ? 158.332 188.804 142.659 1.00 43.58  ? 255 HIS B CD2 1 
ATOM   4828  C CE1 . HIS B 2 239 ? 159.493 190.500 141.896 1.00 53.94  ? 255 HIS B CE1 1 
ATOM   4829  N NE2 . HIS B 2 239 ? 158.713 189.496 141.537 1.00 47.73  ? 255 HIS B NE2 1 
ATOM   4830  N N   . ILE B 2 240 ? 155.710 188.541 145.759 1.00 45.92  ? 256 ILE B N   1 
ATOM   4831  C CA  . ILE B 2 240 ? 154.770 187.461 146.037 1.00 38.08  ? 256 ILE B CA  1 
ATOM   4832  C C   . ILE B 2 240 ? 154.455 186.782 144.711 1.00 36.56  ? 256 ILE B C   1 
ATOM   4833  O O   . ILE B 2 240 ? 154.275 187.453 143.690 1.00 38.18  ? 256 ILE B O   1 
ATOM   4834  C CB  . ILE B 2 240 ? 153.483 187.975 146.721 1.00 40.99  ? 256 ILE B CB  1 
ATOM   4835  C CG1 . ILE B 2 240 ? 153.789 188.528 148.113 1.00 39.33  ? 256 ILE B CG1 1 
ATOM   4836  C CG2 . ILE B 2 240 ? 152.440 186.872 146.825 1.00 36.32  ? 256 ILE B CG2 1 
ATOM   4837  C CD1 . ILE B 2 240 ? 152.787 189.552 148.597 1.00 43.76  ? 256 ILE B CD1 1 
ATOM   4838  N N   . TYR B 2 241 ? 154.401 185.454 144.719 1.00 30.58  ? 257 TYR B N   1 
ATOM   4839  C CA  . TYR B 2 241 ? 154.115 184.676 143.522 1.00 27.86  ? 257 TYR B CA  1 
ATOM   4840  C C   . TYR B 2 241 ? 152.743 184.027 143.641 1.00 30.67  ? 257 TYR B C   1 
ATOM   4841  O O   . TYR B 2 241 ? 152.365 183.542 144.711 1.00 32.03  ? 257 TYR B O   1 
ATOM   4842  C CB  . TYR B 2 241 ? 155.189 183.614 143.289 1.00 26.80  ? 257 TYR B CB  1 
ATOM   4843  C CG  . TYR B 2 241 ? 156.435 184.158 142.633 1.00 24.91  ? 257 TYR B CG  1 
ATOM   4844  C CD1 . TYR B 2 241 ? 156.431 184.534 141.298 1.00 25.01  ? 257 TYR B CD1 1 
ATOM   4845  C CD2 . TYR B 2 241 ? 157.612 184.304 143.349 1.00 25.72  ? 257 TYR B CD2 1 
ATOM   4846  C CE1 . TYR B 2 241 ? 157.564 185.034 140.697 1.00 25.63  ? 257 TYR B CE1 1 
ATOM   4847  C CE2 . TYR B 2 241 ? 158.750 184.804 142.756 1.00 28.16  ? 257 TYR B CE2 1 
ATOM   4848  C CZ  . TYR B 2 241 ? 158.720 185.167 141.430 1.00 28.62  ? 257 TYR B CZ  1 
ATOM   4849  O OH  . TYR B 2 241 ? 159.854 185.665 140.833 1.00 32.80  ? 257 TYR B OH  1 
ATOM   4850  N N   . LEU B 2 242 ? 152.006 184.014 142.534 1.00 30.45  ? 258 LEU B N   1 
ATOM   4851  C CA  . LEU B 2 242 ? 150.584 183.684 142.506 1.00 30.81  ? 258 LEU B CA  1 
ATOM   4852  C C   . LEU B 2 242 ? 150.290 182.622 141.455 1.00 34.91  ? 258 LEU B C   1 
ATOM   4853  O O   . LEU B 2 242 ? 149.439 182.803 140.584 1.00 45.19  ? 258 LEU B O   1 
ATOM   4854  C CB  . LEU B 2 242 ? 149.736 184.924 142.246 1.00 31.98  ? 258 LEU B CB  1 
ATOM   4855  C CG  . LEU B 2 242 ? 149.477 185.891 143.400 1.00 31.81  ? 258 LEU B CG  1 
ATOM   4856  C CD1 . LEU B 2 242 ? 148.175 186.631 143.165 1.00 35.97  ? 258 LEU B CD1 1 
ATOM   4857  C CD2 . LEU B 2 242 ? 149.449 185.173 144.734 1.00 28.98  ? 258 LEU B CD2 1 
ATOM   4858  N N   . ILE B 2 243 ? 151.027 181.509 141.496 1.00 34.68  ? 259 ILE B N   1 
ATOM   4859  C CA  . ILE B 2 243 ? 150.789 180.415 140.560 1.00 34.13  ? 259 ILE B CA  1 
ATOM   4860  C C   . ILE B 2 243 ? 149.323 180.012 140.592 1.00 34.04  ? 259 ILE B C   1 
ATOM   4861  O O   . ILE B 2 243 ? 148.754 179.755 141.658 1.00 32.22  ? 259 ILE B O   1 
ATOM   4862  C CB  . ILE B 2 243 ? 151.705 179.223 140.890 1.00 28.37  ? 259 ILE B CB  1 
ATOM   4863  C CG1 . ILE B 2 243 ? 153.148 179.694 141.064 1.00 27.38  ? 259 ILE B CG1 1 
ATOM   4864  C CG2 . ILE B 2 243 ? 151.605 178.163 139.807 1.00 28.17  ? 259 ILE B CG2 1 
ATOM   4865  C CD1 . ILE B 2 243 ? 154.139 178.571 141.198 1.00 30.73  ? 259 ILE B CD1 1 
ATOM   4866  N N   . GLY B 2 244 ? 148.706 179.959 139.418 1.00 42.12  ? 260 GLY B N   1 
ATOM   4867  C CA  . GLY B 2 244 ? 147.297 179.630 139.319 1.00 48.19  ? 260 GLY B CA  1 
ATOM   4868  C C   . GLY B 2 244 ? 146.890 179.521 137.867 1.00 57.41  ? 260 GLY B C   1 
ATOM   4869  O O   . GLY B 2 244 ? 147.687 179.752 136.953 1.00 60.87  ? 260 GLY B O   1 
ATOM   4870  N N   . LYS B 2 245 ? 145.624 179.169 137.663 1.00 62.70  ? 261 LYS B N   1 
ATOM   4871  C CA  . LYS B 2 245 ? 145.078 178.914 136.336 1.00 71.46  ? 261 LYS B CA  1 
ATOM   4872  C C   . LYS B 2 245 ? 144.157 180.051 135.918 1.00 82.19  ? 261 LYS B C   1 
ATOM   4873  O O   . LYS B 2 245 ? 143.284 180.465 136.688 1.00 82.58  ? 261 LYS B O   1 
ATOM   4874  C CB  . LYS B 2 245 ? 144.315 177.588 136.305 1.00 72.75  ? 261 LYS B CB  1 
ATOM   4875  C CG  . LYS B 2 245 ? 144.999 176.494 135.506 1.00 76.07  ? 261 LYS B CG  1 
ATOM   4876  C CD  . LYS B 2 245 ? 144.816 175.139 136.168 1.00 80.57  ? 261 LYS B CD  1 
ATOM   4877  C CE  . LYS B 2 245 ? 145.702 174.086 135.526 1.00 79.01  ? 261 LYS B CE  1 
ATOM   4878  N NZ  . LYS B 2 245 ? 145.954 172.943 136.445 1.00 76.98  ? 261 LYS B NZ  1 
ATOM   4879  N N   . GLU B 2 246 ? 144.351 180.548 134.700 1.00 89.87  ? 262 GLU B N   1 
ATOM   4880  C CA  . GLU B 2 246 ? 143.484 181.565 134.129 1.00 94.40  ? 262 GLU B CA  1 
ATOM   4881  C C   . GLU B 2 246 ? 142.319 180.921 133.381 1.00 99.29  ? 262 GLU B C   1 
ATOM   4882  O O   . GLU B 2 246 ? 142.260 179.705 133.189 1.00 98.64  ? 262 GLU B O   1 
ATOM   4883  C CB  . GLU B 2 246 ? 144.270 182.480 133.191 1.00 95.59  ? 262 GLU B CB  1 
ATOM   4884  C CG  . GLU B 2 246 ? 144.701 183.793 133.816 1.00 93.42  ? 262 GLU B CG  1 
ATOM   4885  C CD  . GLU B 2 246 ? 144.771 184.922 132.809 1.00 97.81  ? 262 GLU B CD  1 
ATOM   4886  O OE1 . GLU B 2 246 ? 144.753 184.639 131.593 1.00 99.36  ? 262 GLU B OE1 1 
ATOM   4887  O OE2 . GLU B 2 246 ? 144.844 186.094 133.234 1.00 95.03  ? 262 GLU B OE2 1 
ATOM   4888  N N   . SER B 2 247 ? 141.374 181.764 132.958 1.00 104.50 ? 263 SER B N   1 
ATOM   4889  C CA  . SER B 2 247 ? 140.240 181.269 132.184 1.00 109.86 ? 263 SER B CA  1 
ATOM   4890  C C   . SER B 2 247 ? 140.642 180.950 130.749 1.00 112.29 ? 263 SER B C   1 
ATOM   4891  O O   . SER B 2 247 ? 140.189 179.950 130.179 1.00 108.94 ? 263 SER B O   1 
ATOM   4892  C CB  . SER B 2 247 ? 139.104 182.291 132.209 1.00 112.02 ? 263 SER B CB  1 
ATOM   4893  O OG  . SER B 2 247 ? 139.561 183.567 131.795 1.00 110.86 ? 263 SER B OG  1 
ATOM   4894  N N   . SER B 2 248 ? 141.492 181.786 130.148 1.00 113.84 ? 264 SER B N   1 
ATOM   4895  C CA  . SER B 2 248 ? 141.869 181.596 128.751 1.00 112.05 ? 264 SER B CA  1 
ATOM   4896  C C   . SER B 2 248 ? 142.970 180.550 128.607 1.00 109.37 ? 264 SER B C   1 
ATOM   4897  O O   . SER B 2 248 ? 142.775 179.512 127.966 1.00 109.34 ? 264 SER B O   1 
ATOM   4898  C CB  . SER B 2 248 ? 142.310 182.930 128.142 1.00 112.42 ? 264 SER B CB  1 
ATOM   4899  O OG  . SER B 2 248 ? 143.254 183.582 128.973 1.00 112.58 ? 264 SER B OG  1 
ATOM   4900  N N   . ARG B 2 249 ? 144.134 180.807 129.197 1.00 107.44 ? 265 ARG B N   1 
ATOM   4901  C CA  . ARG B 2 249 ? 145.244 179.864 129.134 1.00 107.68 ? 265 ARG B CA  1 
ATOM   4902  C C   . ARG B 2 249 ? 144.984 178.727 130.114 1.00 105.99 ? 265 ARG B C   1 
ATOM   4903  O O   . ARG B 2 249 ? 144.809 178.962 131.314 1.00 102.65 ? 265 ARG B O   1 
ATOM   4904  C CB  . ARG B 2 249 ? 146.563 180.565 129.449 1.00 105.85 ? 265 ARG B CB  1 
ATOM   4905  C CG  . ARG B 2 249 ? 147.796 179.692 129.265 1.00 99.94  ? 265 ARG B CG  1 
ATOM   4906  C CD  . ARG B 2 249 ? 147.762 178.964 127.930 1.00 104.67 ? 265 ARG B CD  1 
ATOM   4907  N NE  . ARG B 2 249 ? 149.098 178.732 127.394 1.00 102.61 ? 265 ARG B NE  1 
ATOM   4908  C CZ  . ARG B 2 249 ? 149.646 179.439 126.414 1.00 101.59 ? 265 ARG B CZ  1 
ATOM   4909  N NH1 . ARG B 2 249 ? 148.998 180.438 125.837 1.00 101.83 ? 265 ARG B NH1 1 
ATOM   4910  N NH2 . ARG B 2 249 ? 150.874 179.136 126.004 1.00 101.09 ? 265 ARG B NH2 1 
ATOM   4911  N N   . THR B 2 250 ? 144.960 177.499 129.605 1.00 104.05 ? 266 THR B N   1 
ATOM   4912  C CA  . THR B 2 250 ? 144.585 176.340 130.404 1.00 102.27 ? 266 THR B CA  1 
ATOM   4913  C C   . THR B 2 250 ? 145.775 175.604 131.007 1.00 93.93  ? 266 THR B C   1 
ATOM   4914  O O   . THR B 2 250 ? 145.572 174.601 131.698 1.00 90.21  ? 266 THR B O   1 
ATOM   4915  C CB  . THR B 2 250 ? 143.760 175.364 129.558 1.00 101.38 ? 266 THR B CB  1 
ATOM   4916  O OG1 . THR B 2 250 ? 144.564 174.859 128.485 1.00 97.87  ? 266 THR B OG1 1 
ATOM   4917  C CG2 . THR B 2 250 ? 142.538 176.062 128.984 1.00 99.62  ? 266 THR B CG2 1 
ATOM   4918  N N   . HIS B 2 251 ? 147.005 176.058 130.765 1.00 89.06  ? 267 HIS B N   1 
ATOM   4919  C CA  . HIS B 2 251 ? 148.159 175.367 131.340 1.00 85.07  ? 267 HIS B CA  1 
ATOM   4920  C C   . HIS B 2 251 ? 148.414 175.812 132.778 1.00 83.81  ? 267 HIS B C   1 
ATOM   4921  O O   . HIS B 2 251 ? 148.220 175.039 133.722 1.00 84.86  ? 267 HIS B O   1 
ATOM   4922  C CB  . HIS B 2 251 ? 149.395 175.605 130.467 1.00 79.18  ? 267 HIS B CB  1 
ATOM   4923  C CG  . HIS B 2 251 ? 149.741 174.452 129.577 1.00 78.48  ? 267 HIS B CG  1 
ATOM   4924  N ND1 . HIS B 2 251 ? 149.863 173.161 130.044 1.00 77.28  ? 267 HIS B ND1 1 
ATOM   4925  C CD2 . HIS B 2 251 ? 149.998 174.397 128.248 1.00 77.32  ? 267 HIS B CD2 1 
ATOM   4926  C CE1 . HIS B 2 251 ? 150.176 172.360 129.041 1.00 76.47  ? 267 HIS B CE1 1 
ATOM   4927  N NE2 . HIS B 2 251 ? 150.264 173.085 127.941 1.00 77.64  ? 267 HIS B NE2 1 
ATOM   4928  N N   . SER B 2 252 ? 148.820 177.073 132.957 1.00 75.03  ? 268 SER B N   1 
ATOM   4929  C CA  . SER B 2 252 ? 149.082 177.664 134.267 1.00 62.92  ? 268 SER B CA  1 
ATOM   4930  C C   . SER B 2 252 ? 149.503 179.118 134.103 1.00 59.28  ? 268 SER B C   1 
ATOM   4931  O O   . SER B 2 252 ? 149.598 179.615 132.977 1.00 66.39  ? 268 SER B O   1 
ATOM   4932  C CB  . SER B 2 252 ? 150.159 176.892 135.029 1.00 60.17  ? 268 SER B CB  1 
ATOM   4933  O OG  . SER B 2 252 ? 149.573 175.953 135.912 1.00 64.61  ? 268 SER B OG  1 
ATOM   4934  N N   . LEU B 2 253 ? 149.766 179.805 135.213 1.00 53.52  ? 269 LEU B N   1 
ATOM   4935  C CA  . LEU B 2 253 ? 150.252 181.178 135.152 1.00 50.30  ? 269 LEU B CA  1 
ATOM   4936  C C   . LEU B 2 253 ? 150.909 181.534 136.475 1.00 45.29  ? 269 LEU B C   1 
ATOM   4937  O O   . LEU B 2 253 ? 150.307 181.348 137.535 1.00 44.11  ? 269 LEU B O   1 
ATOM   4938  C CB  . LEU B 2 253 ? 149.112 182.154 134.845 1.00 53.50  ? 269 LEU B CB  1 
ATOM   4939  C CG  . LEU B 2 253 ? 149.510 183.444 134.130 1.00 52.23  ? 269 LEU B CG  1 
ATOM   4940  C CD1 . LEU B 2 253 ? 149.689 183.193 132.645 1.00 52.81  ? 269 LEU B CD1 1 
ATOM   4941  C CD2 . LEU B 2 253 ? 148.475 184.525 134.371 1.00 59.09  ? 269 LEU B CD2 1 
ATOM   4942  N N   . ALA B 2 254 ? 152.133 182.051 136.408 1.00 41.67  ? 270 ALA B N   1 
ATOM   4943  C CA  . ALA B 2 254 ? 152.860 182.539 137.576 1.00 36.45  ? 270 ALA B CA  1 
ATOM   4944  C C   . ALA B 2 254 ? 152.921 184.059 137.493 1.00 37.36  ? 270 ALA B C   1 
ATOM   4945  O O   . ALA B 2 254 ? 153.550 184.611 136.585 1.00 40.75  ? 270 ALA B O   1 
ATOM   4946  C CB  . ALA B 2 254 ? 154.259 181.933 137.644 1.00 34.55  ? 270 ALA B CB  1 
ATOM   4947  N N   . VAL B 2 255 ? 152.278 184.731 138.444 1.00 38.53  ? 271 VAL B N   1 
ATOM   4948  C CA  . VAL B 2 255 ? 152.133 186.182 138.439 1.00 39.99  ? 271 VAL B CA  1 
ATOM   4949  C C   . VAL B 2 255 ? 152.994 186.767 139.550 1.00 39.19  ? 271 VAL B C   1 
ATOM   4950  O O   . VAL B 2 255 ? 152.964 186.282 140.687 1.00 41.61  ? 271 VAL B O   1 
ATOM   4951  C CB  . VAL B 2 255 ? 150.662 186.598 138.607 1.00 37.25  ? 271 VAL B CB  1 
ATOM   4952  C CG1 . VAL B 2 255 ? 150.465 188.030 138.157 1.00 43.78  ? 271 VAL B CG1 1 
ATOM   4953  C CG2 . VAL B 2 255 ? 149.756 185.663 137.828 1.00 40.73  ? 271 VAL B CG2 1 
ATOM   4954  N N   . SER B 2 256 ? 153.755 187.806 139.221 1.00 39.04  ? 272 SER B N   1 
ATOM   4955  C CA  . SER B 2 256 ? 154.611 188.480 140.186 1.00 42.44  ? 272 SER B CA  1 
ATOM   4956  C C   . SER B 2 256 ? 153.886 189.676 140.787 1.00 49.93  ? 272 SER B C   1 
ATOM   4957  O O   . SER B 2 256 ? 153.158 190.389 140.092 1.00 54.57  ? 272 SER B O   1 
ATOM   4958  C CB  . SER B 2 256 ? 155.911 188.941 139.525 1.00 45.82  ? 272 SER B CB  1 
ATOM   4959  O OG  . SER B 2 256 ? 156.437 187.935 138.679 1.00 49.73  ? 272 SER B OG  1 
ATOM   4960  N N   . LEU B 2 257 ? 154.088 189.890 142.085 1.00 49.57  ? 273 LEU B N   1 
ATOM   4961  C CA  . LEU B 2 257 ? 153.453 190.980 142.812 1.00 50.41  ? 273 LEU B CA  1 
ATOM   4962  C C   . LEU B 2 257 ? 154.513 191.829 143.497 1.00 55.43  ? 273 LEU B C   1 
ATOM   4963  O O   . LEU B 2 257 ? 155.401 191.297 144.169 1.00 53.98  ? 273 LEU B O   1 
ATOM   4964  C CB  . LEU B 2 257 ? 152.460 190.452 143.848 1.00 47.61  ? 273 LEU B CB  1 
ATOM   4965  C CG  . LEU B 2 257 ? 151.268 189.645 143.341 1.00 44.54  ? 273 LEU B CG  1 
ATOM   4966  C CD1 . LEU B 2 257 ? 150.351 189.303 144.498 1.00 42.98  ? 273 LEU B CD1 1 
ATOM   4967  C CD2 . LEU B 2 257 ? 150.519 190.410 142.268 1.00 45.08  ? 273 LEU B CD2 1 
ATOM   4968  N N   . HIS B 2 258 ? 154.410 193.143 143.331 1.00 63.13  ? 274 HIS B N   1 
ATOM   4969  C CA  . HIS B 2 258 ? 155.288 194.099 143.990 1.00 67.75  ? 274 HIS B CA  1 
ATOM   4970  C C   . HIS B 2 258 ? 154.463 194.932 144.958 1.00 70.01  ? 274 HIS B C   1 
ATOM   4971  O O   . HIS B 2 258 ? 153.390 195.425 144.596 1.00 68.25  ? 274 HIS B O   1 
ATOM   4972  C CB  . HIS B 2 258 ? 155.990 195.001 142.972 1.00 67.61  ? 274 HIS B CB  1 
ATOM   4973  C CG  . HIS B 2 258 ? 156.567 196.247 143.566 1.00 74.28  ? 274 HIS B CG  1 
ATOM   4974  N ND1 . HIS B 2 258 ? 157.656 196.233 144.411 1.00 78.17  ? 274 HIS B ND1 1 
ATOM   4975  C CD2 . HIS B 2 258 ? 156.206 197.546 143.440 1.00 74.09  ? 274 HIS B CD2 1 
ATOM   4976  C CE1 . HIS B 2 258 ? 157.941 197.469 144.779 1.00 78.07  ? 274 HIS B CE1 1 
ATOM   4977  N NE2 . HIS B 2 258 ? 157.076 198.285 144.204 1.00 77.09  ? 274 HIS B NE2 1 
ATOM   4978  N N   . CYS B 2 259 ? 154.958 195.082 146.182 1.00 73.00  ? 275 CYS B N   1 
ATOM   4979  C CA  . CYS B 2 259 ? 154.266 195.823 147.229 1.00 75.35  ? 275 CYS B CA  1 
ATOM   4980  C C   . CYS B 2 259 ? 155.057 197.081 147.561 1.00 80.16  ? 275 CYS B C   1 
ATOM   4981  O O   . CYS B 2 259 ? 156.235 197.000 147.923 1.00 79.97  ? 275 CYS B O   1 
ATOM   4982  C CB  . CYS B 2 259 ? 154.080 194.958 148.474 1.00 75.85  ? 275 CYS B CB  1 
ATOM   4983  S SG  . CYS B 2 259 ? 153.892 193.194 148.129 1.00 92.90  ? 275 CYS B SG  1 
ATOM   4984  N N   . ALA B 2 260 ? 154.407 198.235 147.448 1.00 83.19  ? 276 ALA B N   1 
ATOM   4985  C CA  . ALA B 2 260 ? 155.066 199.506 147.697 1.00 86.77  ? 276 ALA B CA  1 
ATOM   4986  C C   . ALA B 2 260 ? 155.130 199.790 149.197 1.00 89.28  ? 276 ALA B C   1 
ATOM   4987  O O   . ALA B 2 260 ? 154.730 198.974 150.032 1.00 88.37  ? 276 ALA B O   1 
ATOM   4988  C CB  . ALA B 2 260 ? 154.351 200.629 146.949 1.00 83.11  ? 276 ALA B CB  1 
ATOM   4989  N N   . GLU B 2 261 ? 155.646 200.971 149.544 1.00 90.56  ? 277 GLU B N   1 
ATOM   4990  C CA  . GLU B 2 261 ? 155.810 201.335 150.947 1.00 89.14  ? 277 GLU B CA  1 
ATOM   4991  C C   . GLU B 2 261 ? 154.484 201.621 151.639 1.00 89.41  ? 277 GLU B C   1 
ATOM   4992  O O   . GLU B 2 261 ? 154.428 201.595 152.873 1.00 86.71  ? 277 GLU B O   1 
ATOM   4993  C CB  . GLU B 2 261 ? 156.738 202.546 151.074 1.00 83.73  ? 277 GLU B CB  1 
ATOM   4994  C CG  . GLU B 2 261 ? 156.065 203.894 150.846 1.00 88.40  ? 277 GLU B CG  1 
ATOM   4995  C CD  . GLU B 2 261 ? 155.485 204.038 149.452 1.00 91.81  ? 277 GLU B CD  1 
ATOM   4996  O OE1 . GLU B 2 261 ? 156.162 203.641 148.480 1.00 90.77  ? 277 GLU B OE1 1 
ATOM   4997  O OE2 . GLU B 2 261 ? 154.353 204.551 149.327 1.00 91.32  ? 277 GLU B OE2 1 
ATOM   4998  N N   . ASP B 2 262 ? 153.419 201.891 150.884 1.00 89.79  ? 278 ASP B N   1 
ATOM   4999  C CA  . ASP B 2 262 ? 152.097 202.111 151.455 1.00 87.44  ? 278 ASP B CA  1 
ATOM   5000  C C   . ASP B 2 262 ? 151.254 200.840 151.480 1.00 85.87  ? 278 ASP B C   1 
ATOM   5001  O O   . ASP B 2 262 ? 150.030 200.923 151.636 1.00 83.76  ? 278 ASP B O   1 
ATOM   5002  C CB  . ASP B 2 262 ? 151.365 203.218 150.693 1.00 89.99  ? 278 ASP B CB  1 
ATOM   5003  C CG  . ASP B 2 262 ? 151.454 203.051 149.192 1.00 91.95  ? 278 ASP B CG  1 
ATOM   5004  O OD1 . ASP B 2 262 ? 152.457 202.484 148.716 1.00 90.19  ? 278 ASP B OD1 1 
ATOM   5005  O OD2 . ASP B 2 262 ? 150.521 203.489 148.488 1.00 92.10  ? 278 ASP B OD2 1 
ATOM   5006  N N   . ASP B 2 263 ? 151.887 199.675 151.330 1.00 86.53  ? 279 ASP B N   1 
ATOM   5007  C CA  . ASP B 2 263 ? 151.227 198.373 151.420 1.00 82.59  ? 279 ASP B CA  1 
ATOM   5008  C C   . ASP B 2 263 ? 150.122 198.232 150.370 1.00 80.43  ? 279 ASP B C   1 
ATOM   5009  O O   . ASP B 2 263 ? 148.938 198.095 150.680 1.00 80.05  ? 279 ASP B O   1 
ATOM   5010  C CB  . ASP B 2 263 ? 150.682 198.140 152.833 1.00 79.66  ? 279 ASP B CB  1 
ATOM   5011  C CG  . ASP B 2 263 ? 151.778 197.845 153.834 1.00 80.72  ? 279 ASP B CG  1 
ATOM   5012  O OD1 . ASP B 2 263 ? 152.838 198.499 153.764 1.00 85.12  ? 279 ASP B OD1 1 
ATOM   5013  O OD2 . ASP B 2 263 ? 151.582 196.961 154.689 1.00 71.73  ? 279 ASP B OD2 1 
ATOM   5014  N N   . SER B 2 264 ? 150.539 198.267 149.106 1.00 79.55  ? 280 SER B N   1 
ATOM   5015  C CA  . SER B 2 264 ? 149.641 198.045 147.978 1.00 76.46  ? 280 SER B CA  1 
ATOM   5016  C C   . SER B 2 264 ? 150.334 197.120 146.991 1.00 75.70  ? 280 SER B C   1 
ATOM   5017  O O   . SER B 2 264 ? 151.465 197.391 146.579 1.00 78.87  ? 280 SER B O   1 
ATOM   5018  C CB  . SER B 2 264 ? 149.259 199.366 147.303 1.00 79.92  ? 280 SER B CB  1 
ATOM   5019  O OG  . SER B 2 264 ? 150.373 199.941 146.642 1.00 81.66  ? 280 SER B OG  1 
ATOM   5020  N N   . ILE B 2 265 ? 149.661 196.038 146.611 1.00 69.42  ? 281 ILE B N   1 
ATOM   5021  C CA  . ILE B 2 265 ? 150.225 195.056 145.692 1.00 69.16  ? 281 ILE B CA  1 
ATOM   5022  C C   . ILE B 2 265 ? 149.837 195.416 144.266 1.00 66.74  ? 281 ILE B C   1 
ATOM   5023  O O   . ILE B 2 265 ? 148.724 195.886 144.005 1.00 68.77  ? 281 ILE B O   1 
ATOM   5024  C CB  . ILE B 2 265 ? 149.763 193.631 146.052 1.00 65.26  ? 281 ILE B CB  1 
ATOM   5025  C CG1 . ILE B 2 265 ? 148.240 193.572 146.181 1.00 68.26  ? 281 ILE B CG1 1 
ATOM   5026  C CG2 . ILE B 2 265 ? 150.433 193.161 147.329 1.00 58.66  ? 281 ILE B CG2 1 
ATOM   5027  C CD1 . ILE B 2 265 ? 147.735 192.344 146.904 1.00 56.64  ? 281 ILE B CD1 1 
ATOM   5028  N N   . SER B 2 266 ? 150.767 195.202 143.338 1.00 64.71  ? 282 SER B N   1 
ATOM   5029  C CA  . SER B 2 266 ? 150.523 195.413 141.920 1.00 62.51  ? 282 SER B CA  1 
ATOM   5030  C C   . SER B 2 266 ? 151.224 194.321 141.128 1.00 59.91  ? 282 SER B C   1 
ATOM   5031  O O   . SER B 2 266 ? 152.215 193.745 141.583 1.00 60.16  ? 282 SER B O   1 
ATOM   5032  C CB  . SER B 2 266 ? 151.008 196.793 141.458 1.00 62.13  ? 282 SER B CB  1 
ATOM   5033  O OG  . SER B 2 266 ? 152.281 197.093 142.001 1.00 64.58  ? 282 SER B OG  1 
ATOM   5034  N N   . VAL B 2 267 ? 150.703 194.043 139.938 1.00 60.78  ? 283 VAL B N   1 
ATOM   5035  C CA  . VAL B 2 267 ? 151.264 193.005 139.080 1.00 58.32  ? 283 VAL B CA  1 
ATOM   5036  C C   . VAL B 2 267 ? 152.489 193.554 138.364 1.00 58.29  ? 283 VAL B C   1 
ATOM   5037  O O   . VAL B 2 267 ? 152.434 194.622 137.742 1.00 61.38  ? 283 VAL B O   1 
ATOM   5038  C CB  . VAL B 2 267 ? 150.213 192.502 138.080 1.00 54.85  ? 283 VAL B CB  1 
ATOM   5039  C CG1 . VAL B 2 267 ? 150.834 191.510 137.116 1.00 52.51  ? 283 VAL B CG1 1 
ATOM   5040  C CG2 . VAL B 2 267 ? 149.044 191.874 138.815 1.00 57.23  ? 283 VAL B CG2 1 
ATOM   5041  N N   . SER B 2 268 ? 153.602 192.826 138.449 1.00 56.51  ? 284 SER B N   1 
ATOM   5042  C CA  . SER B 2 268 ? 154.854 193.243 137.829 1.00 55.69  ? 284 SER B CA  1 
ATOM   5043  C C   . SER B 2 268 ? 155.354 192.258 136.779 1.00 57.12  ? 284 SER B C   1 
ATOM   5044  O O   . SER B 2 268 ? 156.518 192.344 136.372 1.00 58.16  ? 284 SER B O   1 
ATOM   5045  C CB  . SER B 2 268 ? 155.930 193.455 138.896 1.00 56.64  ? 284 SER B CB  1 
ATOM   5046  O OG  . SER B 2 268 ? 155.808 192.508 139.941 1.00 56.04  ? 284 SER B OG  1 
ATOM   5047  N N   . GLY B 2 269 ? 154.520 191.332 136.335 1.00 54.39  ? 285 GLY B N   1 
ATOM   5048  C CA  . GLY B 2 269 ? 154.927 190.388 135.315 1.00 51.73  ? 285 GLY B CA  1 
ATOM   5049  C C   . GLY B 2 269 ? 154.094 189.127 135.380 1.00 48.09  ? 285 GLY B C   1 
ATOM   5050  O O   . GLY B 2 269 ? 153.253 188.951 136.260 1.00 48.69  ? 285 GLY B O   1 
ATOM   5051  N N   . GLN B 2 270 ? 154.348 188.251 134.412 1.00 47.75  ? 286 GLN B N   1 
ATOM   5052  C CA  . GLN B 2 270 ? 153.684 186.956 134.354 1.00 46.79  ? 286 GLN B CA  1 
ATOM   5053  C C   . GLN B 2 270 ? 154.513 186.022 133.486 1.00 49.20  ? 286 GLN B C   1 
ATOM   5054  O O   . GLN B 2 270 ? 155.319 186.462 132.663 1.00 52.70  ? 286 GLN B O   1 
ATOM   5055  C CB  . GLN B 2 270 ? 152.255 187.075 133.815 1.00 46.20  ? 286 GLN B CB  1 
ATOM   5056  C CG  . GLN B 2 270 ? 152.172 187.489 132.361 1.00 50.73  ? 286 GLN B CG  1 
ATOM   5057  C CD  . GLN B 2 270 ? 150.781 187.316 131.790 1.00 56.81  ? 286 GLN B CD  1 
ATOM   5058  O OE1 . GLN B 2 270 ? 149.784 187.510 132.485 1.00 58.59  ? 286 GLN B OE1 1 
ATOM   5059  N NE2 . GLN B 2 270 ? 150.706 186.946 130.517 1.00 56.49  ? 286 GLN B NE2 1 
ATOM   5060  N N   . ASN B 2 271 ? 154.303 184.722 133.684 1.00 47.66  ? 287 ASN B N   1 
ATOM   5061  C CA  . ASN B 2 271 ? 155.078 183.709 132.971 1.00 47.19  ? 287 ASN B CA  1 
ATOM   5062  C C   . ASN B 2 271 ? 154.266 182.422 132.955 1.00 48.73  ? 287 ASN B C   1 
ATOM   5063  O O   . ASN B 2 271 ? 154.105 181.783 133.999 1.00 51.45  ? 287 ASN B O   1 
ATOM   5064  C CB  . ASN B 2 271 ? 156.433 183.499 133.637 1.00 46.74  ? 287 ASN B CB  1 
ATOM   5065  C CG  . ASN B 2 271 ? 157.520 183.138 132.648 1.00 54.60  ? 287 ASN B CG  1 
ATOM   5066  O OD1 . ASN B 2 271 ? 157.356 183.299 131.440 1.00 59.95  ? 287 ASN B OD1 1 
ATOM   5067  N ND2 . ASN B 2 271 ? 158.641 182.646 133.159 1.00 55.23  ? 287 ASN B ND2 1 
ATOM   5068  N N   . SER B 2 272 ? 153.763 182.046 131.783 1.00 47.91  ? 288 SER B N   1 
ATOM   5069  C CA  . SER B 2 272 ? 152.962 180.836 131.668 1.00 48.91  ? 288 SER B CA  1 
ATOM   5070  C C   . SER B 2 272 ? 153.812 179.598 131.925 1.00 47.10  ? 288 SER B C   1 
ATOM   5071  O O   . SER B 2 272 ? 154.958 179.506 131.478 1.00 48.84  ? 288 SER B O   1 
ATOM   5072  C CB  . SER B 2 272 ? 152.322 180.753 130.284 1.00 59.33  ? 288 SER B CB  1 
ATOM   5073  O OG  . SER B 2 272 ? 151.301 179.771 130.252 1.00 67.96  ? 288 SER B OG  1 
ATOM   5074  N N   . LEU B 2 273 ? 153.239 178.643 132.650 1.00 48.37  ? 289 LEU B N   1 
ATOM   5075  C CA  . LEU B 2 273 ? 153.896 177.382 132.963 1.00 48.71  ? 289 LEU B CA  1 
ATOM   5076  C C   . LEU B 2 273 ? 153.355 176.292 132.051 1.00 48.33  ? 289 LEU B C   1 
ATOM   5077  O O   . LEU B 2 273 ? 152.140 176.091 131.971 1.00 55.20  ? 289 LEU B O   1 
ATOM   5078  C CB  . LEU B 2 273 ? 153.674 177.000 134.426 1.00 48.24  ? 289 LEU B CB  1 
ATOM   5079  C CG  . LEU B 2 273 ? 154.828 177.232 135.396 1.00 40.71  ? 289 LEU B CG  1 
ATOM   5080  C CD1 . LEU B 2 273 ? 154.316 177.283 136.823 1.00 34.35  ? 289 LEU B CD1 1 
ATOM   5081  C CD2 . LEU B 2 273 ? 155.871 176.139 135.235 1.00 37.33  ? 289 LEU B CD2 1 
ATOM   5082  N N   . CYS B 2 274 ? 154.256 175.587 131.375 1.00 42.76  ? 290 CYS B N   1 
ATOM   5083  C CA  . CYS B 2 274 ? 153.868 174.566 130.412 1.00 50.77  ? 290 CYS B CA  1 
ATOM   5084  C C   . CYS B 2 274 ? 153.817 173.166 131.008 1.00 48.17  ? 290 CYS B C   1 
ATOM   5085  O O   . CYS B 2 274 ? 153.531 172.210 130.280 1.00 48.48  ? 290 CYS B O   1 
ATOM   5086  C CB  . CYS B 2 274 ? 154.826 174.585 129.217 1.00 55.86  ? 290 CYS B CB  1 
ATOM   5087  S SG  . CYS B 2 274 ? 154.471 175.886 128.009 1.00 83.59  ? 290 CYS B SG  1 
ATOM   5088  N N   . HIS B 2 275 ? 154.082 173.019 132.302 1.00 43.15  ? 291 HIS B N   1 
ATOM   5089  C CA  . HIS B 2 275 ? 154.086 171.727 132.969 1.00 37.13  ? 291 HIS B CA  1 
ATOM   5090  C C   . HIS B 2 275 ? 153.105 171.745 134.133 1.00 37.63  ? 291 HIS B C   1 
ATOM   5091  O O   . HIS B 2 275 ? 152.569 172.790 134.509 1.00 45.39  ? 291 HIS B O   1 
ATOM   5092  C CB  . HIS B 2 275 ? 155.492 171.366 133.465 1.00 32.17  ? 291 HIS B CB  1 
ATOM   5093  C CG  . HIS B 2 275 ? 156.502 171.215 132.370 1.00 34.05  ? 291 HIS B CG  1 
ATOM   5094  N ND1 . HIS B 2 275 ? 157.389 172.214 132.032 1.00 33.06  ? 291 HIS B ND1 1 
ATOM   5095  C CD2 . HIS B 2 275 ? 156.766 170.181 131.537 1.00 31.76  ? 291 HIS B CD2 1 
ATOM   5096  C CE1 . HIS B 2 275 ? 158.155 171.802 131.038 1.00 29.46  ? 291 HIS B CE1 1 
ATOM   5097  N NE2 . HIS B 2 275 ? 157.798 170.572 130.719 1.00 28.66  ? 291 HIS B NE2 1 
ATOM   5098  N N   . GLN B 2 276 ? 152.869 170.569 134.704 1.00 33.22  ? 292 GLN B N   1 
ATOM   5099  C CA  . GLN B 2 276 ? 152.014 170.434 135.873 1.00 30.72  ? 292 GLN B CA  1 
ATOM   5100  C C   . GLN B 2 276 ? 152.881 170.409 137.125 1.00 28.09  ? 292 GLN B C   1 
ATOM   5101  O O   . GLN B 2 276 ? 153.934 169.765 137.155 1.00 30.55  ? 292 GLN B O   1 
ATOM   5102  C CB  . GLN B 2 276 ? 151.132 169.184 135.772 1.00 36.23  ? 292 GLN B CB  1 
ATOM   5103  C CG  . GLN B 2 276 ? 151.569 167.981 136.585 1.00 42.03  ? 292 GLN B CG  1 
ATOM   5104  C CD  . GLN B 2 276 ? 150.713 166.759 136.307 1.00 45.76  ? 292 GLN B CD  1 
ATOM   5105  O OE1 . GLN B 2 276 ? 150.345 166.024 137.223 1.00 44.54  ? 292 GLN B OE1 1 
ATOM   5106  N NE2 . GLN B 2 276 ? 150.397 166.534 135.039 1.00 43.41  ? 292 GLN B NE2 1 
ATOM   5107  N N   . ILE B 2 277 ? 152.451 171.148 138.144 1.00 29.38  ? 293 ILE B N   1 
ATOM   5108  C CA  . ILE B 2 277 ? 153.283 171.491 139.292 1.00 25.09  ? 293 ILE B CA  1 
ATOM   5109  C C   . ILE B 2 277 ? 152.722 170.809 140.530 1.00 23.76  ? 293 ILE B C   1 
ATOM   5110  O O   . ILE B 2 277 ? 151.511 170.845 140.772 1.00 26.57  ? 293 ILE B O   1 
ATOM   5111  C CB  . ILE B 2 277 ? 153.357 173.016 139.487 1.00 22.90  ? 293 ILE B CB  1 
ATOM   5112  C CG1 . ILE B 2 277 ? 153.912 173.688 138.231 1.00 26.28  ? 293 ILE B CG1 1 
ATOM   5113  C CG2 . ILE B 2 277 ? 154.207 173.368 140.688 1.00 20.82  ? 293 ILE B CG2 1 
ATOM   5114  C CD1 . ILE B 2 277 ? 155.203 173.076 137.733 1.00 27.57  ? 293 ILE B CD1 1 
ATOM   5115  N N   . THR B 2 278 ? 153.605 170.180 141.308 1.00 20.60  ? 294 THR B N   1 
ATOM   5116  C CA  . THR B 2 278 ? 153.225 169.564 142.569 1.00 22.02  ? 294 THR B CA  1 
ATOM   5117  C C   . THR B 2 278 ? 153.745 170.307 143.791 1.00 23.01  ? 294 THR B C   1 
ATOM   5118  O O   . THR B 2 278 ? 153.249 170.065 144.895 1.00 27.21  ? 294 THR B O   1 
ATOM   5119  C CB  . THR B 2 278 ? 153.718 168.109 142.629 1.00 25.77  ? 294 THR B CB  1 
ATOM   5120  O OG1 . THR B 2 278 ? 155.119 168.083 142.924 1.00 25.25  ? 294 THR B OG1 1 
ATOM   5121  C CG2 . THR B 2 278 ? 153.474 167.407 141.302 1.00 24.05  ? 294 THR B CG2 1 
ATOM   5122  N N   . ALA B 2 279 ? 154.720 171.196 143.625 1.00 20.54  ? 295 ALA B N   1 
ATOM   5123  C CA  . ALA B 2 279 ? 155.242 171.988 144.729 1.00 18.53  ? 295 ALA B CA  1 
ATOM   5124  C C   . ALA B 2 279 ? 155.923 173.222 144.162 1.00 18.93  ? 295 ALA B C   1 
ATOM   5125  O O   . ALA B 2 279 ? 156.399 173.213 143.026 1.00 20.08  ? 295 ALA B O   1 
ATOM   5126  C CB  . ALA B 2 279 ? 156.220 171.185 145.591 1.00 19.44  ? 295 ALA B CB  1 
ATOM   5127  N N   . ALA B 2 280 ? 155.967 174.280 144.967 1.00 17.69  ? 296 ALA B N   1 
ATOM   5128  C CA  . ALA B 2 280 ? 156.569 175.537 144.552 1.00 16.30  ? 296 ALA B CA  1 
ATOM   5129  C C   . ALA B 2 280 ? 157.225 176.204 145.751 1.00 20.27  ? 296 ALA B C   1 
ATOM   5130  O O   . ALA B 2 280 ? 156.850 175.971 146.902 1.00 23.87  ? 296 ALA B O   1 
ATOM   5131  C CB  . ALA B 2 280 ? 155.538 176.475 143.916 1.00 17.81  ? 296 ALA B CB  1 
ATOM   5132  N N   . CYS B 2 281 ? 158.216 177.045 145.463 1.00 19.96  ? 297 CYS B N   1 
ATOM   5133  C CA  . CYS B 2 281 ? 158.974 177.731 146.497 1.00 17.37  ? 297 CYS B CA  1 
ATOM   5134  C C   . CYS B 2 281 ? 159.516 179.031 145.922 1.00 19.55  ? 297 CYS B C   1 
ATOM   5135  O O   . CYS B 2 281 ? 159.564 179.220 144.706 1.00 22.63  ? 297 CYS B O   1 
ATOM   5136  C CB  . CYS B 2 281 ? 160.107 176.849 147.035 1.00 19.11  ? 297 CYS B CB  1 
ATOM   5137  S SG  . CYS B 2 281 ? 161.349 177.706 148.010 1.00 30.51  ? 297 CYS B SG  1 
ATOM   5138  N N   . LYS B 2 282 ? 159.922 179.930 146.812 1.00 22.95  ? 298 LYS B N   1 
ATOM   5139  C CA  . LYS B 2 282 ? 160.335 181.284 146.452 1.00 24.61  ? 298 LYS B CA  1 
ATOM   5140  C C   . LYS B 2 282 ? 161.669 181.630 147.103 1.00 28.82  ? 298 LYS B C   1 
ATOM   5141  O O   . LYS B 2 282 ? 161.801 182.622 147.821 1.00 34.60  ? 298 LYS B O   1 
ATOM   5142  C CB  . LYS B 2 282 ? 159.270 182.308 146.828 1.00 25.56  ? 298 LYS B CB  1 
ATOM   5143  C CG  . LYS B 2 282 ? 159.518 183.684 146.232 1.00 25.19  ? 298 LYS B CG  1 
ATOM   5144  C CD  . LYS B 2 282 ? 158.691 184.738 146.919 1.00 29.38  ? 298 LYS B CD  1 
ATOM   5145  C CE  . LYS B 2 282 ? 159.392 186.075 146.880 1.00 29.94  ? 298 LYS B CE  1 
ATOM   5146  N NZ  . LYS B 2 282 ? 160.425 186.176 147.947 1.00 30.18  ? 298 LYS B NZ  1 
ATOM   5147  N N   . HIS B 2 283 ? 162.670 180.774 146.911 1.00 26.52  ? 299 HIS B N   1 
ATOM   5148  C CA  . HIS B 2 283 ? 164.001 181.056 147.434 1.00 26.61  ? 299 HIS B CA  1 
ATOM   5149  C C   . HIS B 2 283 ? 164.539 182.378 146.902 1.00 28.20  ? 299 HIS B C   1 
ATOM   5150  O O   . HIS B 2 283 ? 164.798 182.511 145.703 1.00 29.14  ? 299 HIS B O   1 
ATOM   5151  C CB  . HIS B 2 283 ? 164.968 179.924 147.090 1.00 27.26  ? 299 HIS B CB  1 
ATOM   5152  C CG  . HIS B 2 283 ? 166.310 180.064 147.737 1.00 25.19  ? 299 HIS B CG  1 
ATOM   5153  N ND1 . HIS B 2 283 ? 166.543 179.717 149.049 1.00 24.80  ? 299 HIS B ND1 1 
ATOM   5154  C CD2 . HIS B 2 283 ? 167.487 180.525 147.255 1.00 24.41  ? 299 HIS B CD2 1 
ATOM   5155  C CE1 . HIS B 2 283 ? 167.807 179.952 149.346 1.00 25.58  ? 299 HIS B CE1 1 
ATOM   5156  N NE2 . HIS B 2 283 ? 168.402 180.444 148.276 1.00 25.47  ? 299 HIS B NE2 1 
ATOM   5157  N N   . GLY B 2 284 ? 164.716 183.355 147.789 1.00 31.64  ? 300 GLY B N   1 
ATOM   5158  C CA  . GLY B 2 284 ? 165.231 184.647 147.369 1.00 31.16  ? 300 GLY B CA  1 
ATOM   5159  C C   . GLY B 2 284 ? 164.220 185.401 146.529 1.00 32.41  ? 300 GLY B C   1 
ATOM   5160  O O   . GLY B 2 284 ? 163.056 185.566 146.908 1.00 35.96  ? 300 GLY B O   1 
ATOM   5161  N N   . GLY B 2 285 ? 164.672 185.879 145.376 1.00 30.20  ? 301 GLY B N   1 
ATOM   5162  C CA  . GLY B 2 285 ? 163.800 186.508 144.411 1.00 31.04  ? 301 GLY B CA  1 
ATOM   5163  C C   . GLY B 2 285 ? 163.384 185.623 143.264 1.00 38.94  ? 301 GLY B C   1 
ATOM   5164  O O   . GLY B 2 285 ? 162.707 186.091 142.344 1.00 40.48  ? 301 GLY B O   1 
ATOM   5165  N N   . ASP B 2 286 ? 163.768 184.351 143.291 1.00 37.06  ? 302 ASP B N   1 
ATOM   5166  C CA  . ASP B 2 286 ? 163.465 183.403 142.231 1.00 33.06  ? 302 ASP B CA  1 
ATOM   5167  C C   . ASP B 2 286 ? 162.301 182.505 142.631 1.00 30.93  ? 302 ASP B C   1 
ATOM   5168  O O   . ASP B 2 286 ? 161.935 182.396 143.802 1.00 30.86  ? 302 ASP B O   1 
ATOM   5169  C CB  . ASP B 2 286 ? 164.697 182.557 141.903 1.00 33.70  ? 302 ASP B CB  1 
ATOM   5170  C CG  . ASP B 2 286 ? 165.823 183.375 141.312 1.00 45.78  ? 302 ASP B CG  1 
ATOM   5171  O OD1 . ASP B 2 286 ? 165.892 184.587 141.601 1.00 48.02  ? 302 ASP B OD1 1 
ATOM   5172  O OD2 . ASP B 2 286 ? 166.641 182.807 140.559 1.00 46.90  ? 302 ASP B OD2 1 
ATOM   5173  N N   . LEU B 2 287 ? 161.717 181.855 141.630 1.00 28.39  ? 303 LEU B N   1 
ATOM   5174  C CA  . LEU B 2 287 ? 160.624 180.916 141.828 1.00 22.33  ? 303 LEU B CA  1 
ATOM   5175  C C   . LEU B 2 287 ? 161.069 179.530 141.387 1.00 25.60  ? 303 LEU B C   1 
ATOM   5176  O O   . LEU B 2 287 ? 161.519 179.350 140.251 1.00 26.32  ? 303 LEU B O   1 
ATOM   5177  C CB  . LEU B 2 287 ? 159.379 181.349 141.052 1.00 21.33  ? 303 LEU B CB  1 
ATOM   5178  C CG  . LEU B 2 287 ? 158.161 180.431 141.145 1.00 19.87  ? 303 LEU B CG  1 
ATOM   5179  C CD1 . LEU B 2 287 ? 157.508 180.543 142.510 1.00 19.15  ? 303 LEU B CD1 1 
ATOM   5180  C CD2 . LEU B 2 287 ? 157.171 180.758 140.047 1.00 23.23  ? 303 LEU B CD2 1 
ATOM   5181  N N   . TYR B 2 288 ? 160.943 178.560 142.285 1.00 23.44  ? 304 TYR B N   1 
ATOM   5182  C CA  . TYR B 2 288 ? 161.280 177.170 142.014 1.00 18.65  ? 304 TYR B CA  1 
ATOM   5183  C C   . TYR B 2 288 ? 160.005 176.341 142.025 1.00 18.59  ? 304 TYR B C   1 
ATOM   5184  O O   . TYR B 2 288 ? 159.229 176.409 142.982 1.00 19.93  ? 304 TYR B O   1 
ATOM   5185  C CB  . TYR B 2 288 ? 162.261 176.631 143.056 1.00 19.30  ? 304 TYR B CB  1 
ATOM   5186  C CG  . TYR B 2 288 ? 163.673 177.151 142.919 1.00 22.57  ? 304 TYR B CG  1 
ATOM   5187  C CD1 . TYR B 2 288 ? 164.033 178.383 143.442 1.00 21.49  ? 304 TYR B CD1 1 
ATOM   5188  C CD2 . TYR B 2 288 ? 164.648 176.400 142.280 1.00 21.61  ? 304 TYR B CD2 1 
ATOM   5189  C CE1 . TYR B 2 288 ? 165.322 178.858 143.323 1.00 24.17  ? 304 TYR B CE1 1 
ATOM   5190  C CE2 . TYR B 2 288 ? 165.938 176.865 142.158 1.00 20.67  ? 304 TYR B CE2 1 
ATOM   5191  C CZ  . TYR B 2 288 ? 166.270 178.094 142.681 1.00 25.36  ? 304 TYR B CZ  1 
ATOM   5192  O OH  . TYR B 2 288 ? 167.557 178.561 142.560 1.00 29.40  ? 304 TYR B OH  1 
ATOM   5193  N N   . VAL B 2 289 ? 159.793 175.561 140.970 1.00 20.35  ? 305 VAL B N   1 
ATOM   5194  C CA  . VAL B 2 289 ? 158.627 174.695 140.851 1.00 17.62  ? 305 VAL B CA  1 
ATOM   5195  C C   . VAL B 2 289 ? 159.101 173.260 140.683 1.00 17.17  ? 305 VAL B C   1 
ATOM   5196  O O   . VAL B 2 289 ? 160.126 173.004 140.044 1.00 22.54  ? 305 VAL B O   1 
ATOM   5197  C CB  . VAL B 2 289 ? 157.711 175.112 139.681 1.00 18.78  ? 305 VAL B CB  1 
ATOM   5198  C CG1 . VAL B 2 289 ? 157.157 176.508 139.908 1.00 19.91  ? 305 VAL B CG1 1 
ATOM   5199  C CG2 . VAL B 2 289 ? 158.450 175.039 138.362 1.00 19.06  ? 305 VAL B CG2 1 
ATOM   5200  N N   . VAL B 2 290 ? 158.365 172.328 141.281 1.00 16.48  ? 306 VAL B N   1 
ATOM   5201  C CA  . VAL B 2 290 ? 158.642 170.900 141.178 1.00 20.14  ? 306 VAL B CA  1 
ATOM   5202  C C   . VAL B 2 290 ? 157.420 170.231 140.570 1.00 20.86  ? 306 VAL B C   1 
ATOM   5203  O O   . VAL B 2 290 ? 156.290 170.487 140.999 1.00 23.84  ? 306 VAL B O   1 
ATOM   5204  C CB  . VAL B 2 290 ? 158.983 170.284 142.548 1.00 19.64  ? 306 VAL B CB  1 
ATOM   5205  C CG1 . VAL B 2 290 ? 159.070 168.771 142.446 1.00 18.14  ? 306 VAL B CG1 1 
ATOM   5206  C CG2 . VAL B 2 290 ? 160.282 170.859 143.082 1.00 17.79  ? 306 VAL B CG2 1 
ATOM   5207  N N   . GLY B 2 291 ? 157.642 169.383 139.571 1.00 18.09  ? 307 GLY B N   1 
ATOM   5208  C CA  . GLY B 2 291 ? 156.532 168.732 138.909 1.00 18.97  ? 307 GLY B CA  1 
ATOM   5209  C C   . GLY B 2 291 ? 156.932 167.777 137.807 1.00 20.83  ? 307 GLY B C   1 
ATOM   5210  O O   . GLY B 2 291 ? 157.857 166.977 137.968 1.00 22.19  ? 307 GLY B O   1 
ATOM   5211  N N   . GLY B 2 292 ? 156.238 167.856 136.676 1.00 22.06  ? 308 GLY B N   1 
ATOM   5212  C CA  . GLY B 2 292 ? 156.415 166.897 135.607 1.00 24.02  ? 308 GLY B CA  1 
ATOM   5213  C C   . GLY B 2 292 ? 155.176 166.054 135.395 1.00 29.11  ? 308 GLY B C   1 
ATOM   5214  O O   . GLY B 2 292 ? 154.163 166.546 134.892 1.00 32.71  ? 308 GLY B O   1 
ATOM   5215  N N   . SER B 2 293 ? 155.245 164.783 135.765 1.00 28.09  ? 309 SER B N   1 
ATOM   5216  C CA  . SER B 2 293 ? 154.119 163.866 135.677 1.00 29.88  ? 309 SER B CA  1 
ATOM   5217  C C   . SER B 2 293 ? 153.775 163.355 137.072 1.00 32.82  ? 309 SER B C   1 
ATOM   5218  O O   . SER B 2 293 ? 154.455 163.657 138.053 1.00 32.53  ? 309 SER B O   1 
ATOM   5219  C CB  . SER B 2 293 ? 154.431 162.707 134.728 1.00 37.27  ? 309 SER B CB  1 
ATOM   5220  O OG  . SER B 2 293 ? 155.252 161.739 135.356 1.00 33.24  ? 309 SER B OG  1 
ATOM   5221  N N   . ILE B 2 294 ? 152.700 162.581 137.156 1.00 34.33  ? 310 ILE B N   1 
ATOM   5222  C CA  . ILE B 2 294 ? 152.253 162.015 138.427 1.00 32.68  ? 310 ILE B CA  1 
ATOM   5223  C C   . ILE B 2 294 ? 153.095 160.797 138.803 1.00 34.83  ? 310 ILE B C   1 
ATOM   5224  O O   . ILE B 2 294 ? 153.490 160.680 139.971 1.00 37.98  ? 310 ILE B O   1 
ATOM   5225  C CB  . ILE B 2 294 ? 150.754 161.674 138.389 1.00 40.56  ? 310 ILE B CB  1 
ATOM   5226  C CG1 . ILE B 2 294 ? 149.921 162.954 138.460 1.00 42.44  ? 310 ILE B CG1 1 
ATOM   5227  C CG2 . ILE B 2 294 ? 150.382 160.737 139.527 1.00 36.57  ? 310 ILE B CG2 1 
ATOM   5228  C CD1 . ILE B 2 294 ? 149.960 163.634 139.812 1.00 38.55  ? 310 ILE B CD1 1 
ATOM   5229  N N   . PRO B 2 295 ? 153.381 159.855 137.888 1.00 31.78  ? 311 PRO B N   1 
ATOM   5230  C CA  . PRO B 2 295 ? 154.268 158.743 138.275 1.00 27.69  ? 311 PRO B CA  1 
ATOM   5231  C C   . PRO B 2 295 ? 155.664 159.180 138.688 1.00 26.54  ? 311 PRO B C   1 
ATOM   5232  O O   . PRO B 2 295 ? 156.250 158.573 139.592 1.00 24.97  ? 311 PRO B O   1 
ATOM   5233  C CB  . PRO B 2 295 ? 154.293 157.868 137.015 1.00 27.56  ? 311 PRO B CB  1 
ATOM   5234  C CG  . PRO B 2 295 ? 153.014 158.167 136.341 1.00 30.77  ? 311 PRO B CG  1 
ATOM   5235  C CD  . PRO B 2 295 ? 152.817 159.632 136.544 1.00 30.19  ? 311 PRO B CD  1 
ATOM   5236  N N   . ARG B 2 296 ? 156.218 160.215 138.055 1.00 25.47  ? 312 ARG B N   1 
ATOM   5237  C CA  . ARG B 2 296 ? 157.559 160.714 138.365 1.00 22.25  ? 312 ARG B CA  1 
ATOM   5238  C C   . ARG B 2 296 ? 157.530 162.229 138.536 1.00 24.98  ? 312 ARG B C   1 
ATOM   5239  O O   . ARG B 2 296 ? 157.973 162.974 137.655 1.00 26.65  ? 312 ARG B O   1 
ATOM   5240  C CB  . ARG B 2 296 ? 158.557 160.324 137.274 1.00 19.78  ? 312 ARG B CB  1 
ATOM   5241  C CG  . ARG B 2 296 ? 158.567 158.860 136.883 1.00 13.91  ? 312 ARG B CG  1 
ATOM   5242  C CD  . ARG B 2 296 ? 159.631 158.615 135.832 1.00 12.85  ? 312 ARG B CD  1 
ATOM   5243  N NE  . ARG B 2 296 ? 159.343 157.461 134.990 1.00 13.73  ? 312 ARG B NE  1 
ATOM   5244  C CZ  . ARG B 2 296 ? 160.244 156.838 134.243 1.00 12.35  ? 312 ARG B CZ  1 
ATOM   5245  N NH1 . ARG B 2 296 ? 161.503 157.237 134.204 1.00 12.19  ? 312 ARG B NH1 1 
ATOM   5246  N NH2 . ARG B 2 296 ? 159.873 155.791 133.515 1.00 11.72  ? 312 ARG B NH2 1 
ATOM   5247  N N   . PRO B 2 297 ? 157.013 162.725 139.668 1.00 27.00  ? 313 PRO B N   1 
ATOM   5248  C CA  . PRO B 2 297 ? 157.027 164.183 139.920 1.00 24.80  ? 313 PRO B CA  1 
ATOM   5249  C C   . PRO B 2 297 ? 158.326 164.651 140.571 1.00 26.69  ? 313 PRO B C   1 
ATOM   5250  O O   . PRO B 2 297 ? 158.368 165.103 141.723 1.00 31.05  ? 313 PRO B O   1 
ATOM   5251  C CB  . PRO B 2 297 ? 155.816 164.362 140.836 1.00 25.93  ? 313 PRO B CB  1 
ATOM   5252  C CG  . PRO B 2 297 ? 155.779 163.097 141.618 1.00 26.35  ? 313 PRO B CG  1 
ATOM   5253  C CD  . PRO B 2 297 ? 156.224 162.006 140.683 1.00 26.06  ? 313 PRO B CD  1 
ATOM   5254  N N   . ARG B 2 298 ? 159.423 164.556 139.820 1.00 22.00  ? 314 ARG B N   1 
ATOM   5255  C CA  . ARG B 2 298 ? 160.744 164.853 140.349 1.00 18.26  ? 314 ARG B CA  1 
ATOM   5256  C C   . ARG B 2 298 ? 161.492 165.936 139.586 1.00 19.07  ? 314 ARG B C   1 
ATOM   5257  O O   . ARG B 2 298 ? 162.577 166.331 140.023 1.00 19.92  ? 314 ARG B O   1 
ATOM   5258  C CB  . ARG B 2 298 ? 161.604 163.580 140.371 1.00 19.89  ? 314 ARG B CB  1 
ATOM   5259  C CG  . ARG B 2 298 ? 161.754 162.918 139.013 1.00 21.59  ? 314 ARG B CG  1 
ATOM   5260  C CD  . ARG B 2 298 ? 162.752 161.779 139.056 1.00 19.48  ? 314 ARG B CD  1 
ATOM   5261  N NE  . ARG B 2 298 ? 162.103 160.499 139.306 1.00 20.07  ? 314 ARG B NE  1 
ATOM   5262  C CZ  . ARG B 2 298 ? 162.361 159.384 138.638 1.00 16.01  ? 314 ARG B CZ  1 
ATOM   5263  N NH1 . ARG B 2 298 ? 163.257 159.352 137.668 1.00 12.69  ? 314 ARG B NH1 1 
ATOM   5264  N NH2 . ARG B 2 298 ? 161.702 158.273 138.951 1.00 15.05  ? 314 ARG B NH2 1 
ATOM   5265  N N   . ARG B 2 299 ? 160.958 166.426 138.473 1.00 20.39  ? 315 ARG B N   1 
ATOM   5266  C CA  . ARG B 2 299 ? 161.645 167.439 137.689 1.00 17.32  ? 315 ARG B CA  1 
ATOM   5267  C C   . ARG B 2 299 ? 161.474 168.816 138.322 1.00 20.12  ? 315 ARG B C   1 
ATOM   5268  O O   . ARG B 2 299 ? 160.433 169.134 138.900 1.00 22.53  ? 315 ARG B O   1 
ATOM   5269  C CB  . ARG B 2 299 ? 161.127 167.441 136.251 1.00 16.29  ? 315 ARG B CB  1 
ATOM   5270  C CG  . ARG B 2 299 ? 161.797 166.406 135.358 1.00 17.69  ? 315 ARG B CG  1 
ATOM   5271  C CD  . ARG B 2 299 ? 161.436 166.595 133.895 1.00 19.17  ? 315 ARG B CD  1 
ATOM   5272  N NE  . ARG B 2 299 ? 160.032 166.304 133.635 1.00 21.21  ? 315 ARG B NE  1 
ATOM   5273  C CZ  . ARG B 2 299 ? 159.407 166.580 132.499 1.00 19.45  ? 315 ARG B CZ  1 
ATOM   5274  N NH1 . ARG B 2 299 ? 160.033 167.160 131.490 1.00 19.80  ? 315 ARG B NH1 1 
ATOM   5275  N NH2 . ARG B 2 299 ? 158.122 166.265 132.374 1.00 18.85  ? 315 ARG B NH2 1 
ATOM   5276  N N   . MET B 2 300 ? 162.518 169.635 138.209 1.00 19.20  ? 316 MET B N   1 
ATOM   5277  C CA  . MET B 2 300 ? 162.569 170.940 138.853 1.00 17.25  ? 316 MET B CA  1 
ATOM   5278  C C   . MET B 2 300 ? 162.945 172.012 137.841 1.00 17.42  ? 316 MET B C   1 
ATOM   5279  O O   . MET B 2 300 ? 163.769 171.779 136.953 1.00 17.79  ? 316 MET B O   1 
ATOM   5280  C CB  . MET B 2 300 ? 163.575 170.940 140.006 1.00 19.30  ? 316 MET B CB  1 
ATOM   5281  C CG  . MET B 2 300 ? 163.285 171.952 141.099 1.00 18.93  ? 316 MET B CG  1 
ATOM   5282  S SD  . MET B 2 300 ? 164.712 172.203 142.166 1.00 26.85  ? 316 MET B SD  1 
ATOM   5283  C CE  . MET B 2 300 ? 163.952 173.040 143.548 1.00 15.54  ? 316 MET B CE  1 
ATOM   5284  N N   . TRP B 2 301 ? 162.339 173.188 137.988 1.00 19.97  ? 317 TRP B N   1 
ATOM   5285  C CA  . TRP B 2 301 ? 162.603 174.334 137.132 1.00 19.79  ? 317 TRP B CA  1 
ATOM   5286  C C   . TRP B 2 301 ? 162.798 175.574 137.992 1.00 23.36  ? 317 TRP B C   1 
ATOM   5287  O O   . TRP B 2 301 ? 162.373 175.627 139.147 1.00 23.48  ? 317 TRP B O   1 
ATOM   5288  C CB  . TRP B 2 301 ? 161.465 174.576 136.128 1.00 20.57  ? 317 TRP B CB  1 
ATOM   5289  C CG  . TRP B 2 301 ? 161.279 173.471 135.140 1.00 19.88  ? 317 TRP B CG  1 
ATOM   5290  C CD1 . TRP B 2 301 ? 161.892 173.342 133.930 1.00 19.16  ? 317 TRP B CD1 1 
ATOM   5291  C CD2 . TRP B 2 301 ? 160.415 172.337 135.274 1.00 20.25  ? 317 TRP B CD2 1 
ATOM   5292  N NE1 . TRP B 2 301 ? 161.468 172.197 133.305 1.00 19.80  ? 317 TRP B NE1 1 
ATOM   5293  C CE2 . TRP B 2 301 ? 160.560 171.562 134.110 1.00 19.31  ? 317 TRP B CE2 1 
ATOM   5294  C CE3 . TRP B 2 301 ? 159.534 171.901 136.268 1.00 18.27  ? 317 TRP B CE3 1 
ATOM   5295  C CZ2 . TRP B 2 301 ? 159.858 170.381 133.911 1.00 19.92  ? 317 TRP B CZ2 1 
ATOM   5296  C CZ3 . TRP B 2 301 ? 158.839 170.730 136.067 1.00 19.21  ? 317 TRP B CZ3 1 
ATOM   5297  C CH2 . TRP B 2 301 ? 159.004 169.982 134.900 1.00 18.85  ? 317 TRP B CH2 1 
ATOM   5298  N N   . LYS B 2 302 ? 163.454 176.576 137.412 1.00 26.96  ? 318 LYS B N   1 
ATOM   5299  C CA  . LYS B 2 302 ? 163.693 177.853 138.068 1.00 28.21  ? 318 LYS B CA  1 
ATOM   5300  C C   . LYS B 2 302 ? 163.329 178.988 137.124 1.00 32.57  ? 318 LYS B C   1 
ATOM   5301  O O   . LYS B 2 302 ? 163.605 178.919 135.924 1.00 37.80  ? 318 LYS B O   1 
ATOM   5302  C CB  . LYS B 2 302 ? 165.152 177.990 138.504 1.00 27.87  ? 318 LYS B CB  1 
ATOM   5303  C CG  . LYS B 2 302 ? 165.420 179.178 139.405 1.00 29.32  ? 318 LYS B CG  1 
ATOM   5304  C CD  . LYS B 2 302 ? 166.705 179.892 139.020 1.00 35.54  ? 318 LYS B CD  1 
ATOM   5305  C CE  . LYS B 2 302 ? 167.761 178.919 138.526 1.00 34.72  ? 318 LYS B CE  1 
ATOM   5306  N NZ  . LYS B 2 302 ? 169.133 179.475 138.667 1.00 39.51  ? 318 LYS B NZ  1 
ATOM   5307  N N   . CYS B 2 303 ? 162.717 180.035 137.670 1.00 36.11  ? 319 CYS B N   1 
ATOM   5308  C CA  . CYS B 2 303 ? 162.285 181.181 136.885 1.00 39.93  ? 319 CYS B CA  1 
ATOM   5309  C C   . CYS B 2 303 ? 162.729 182.476 137.546 1.00 46.60  ? 319 CYS B C   1 
ATOM   5310  O O   . CYS B 2 303 ? 162.842 182.566 138.770 1.00 41.60  ? 319 CYS B O   1 
ATOM   5311  C CB  . CYS B 2 303 ? 160.765 181.204 136.709 1.00 40.42  ? 319 CYS B CB  1 
ATOM   5312  S SG  . CYS B 2 303 ? 160.094 182.791 136.176 1.00 58.72  ? 319 CYS B SG  1 
ATOM   5313  N N   . ASN B 2 304 ? 162.978 183.480 136.712 1.00 61.49  ? 320 ASN B N   1 
ATOM   5314  C CA  . ASN B 2 304 ? 163.261 184.836 137.155 1.00 63.44  ? 320 ASN B CA  1 
ATOM   5315  C C   . ASN B 2 304 ? 162.397 185.797 136.354 1.00 68.12  ? 320 ASN B C   1 
ATOM   5316  O O   . ASN B 2 304 ? 162.169 185.590 135.159 1.00 69.23  ? 320 ASN B O   1 
ATOM   5317  C CB  . ASN B 2 304 ? 164.740 185.187 136.984 1.00 62.20  ? 320 ASN B CB  1 
ATOM   5318  C CG  . ASN B 2 304 ? 165.319 185.863 138.205 1.00 60.72  ? 320 ASN B CG  1 
ATOM   5319  O OD1 . ASN B 2 304 ? 164.594 186.468 138.994 1.00 60.50  ? 320 ASN B OD1 1 
ATOM   5320  N ND2 . ASN B 2 304 ? 166.632 185.763 138.371 1.00 59.10  ? 320 ASN B ND2 1 
ATOM   5321  N N   . ASN B 2 305 ? 161.906 186.844 137.021 1.00 68.25  ? 321 ASN B N   1 
ATOM   5322  C CA  . ASN B 2 305 ? 161.053 187.811 136.339 1.00 74.40  ? 321 ASN B CA  1 
ATOM   5323  C C   . ASN B 2 305 ? 161.805 188.533 135.227 1.00 75.74  ? 321 ASN B C   1 
ATOM   5324  O O   . ASN B 2 305 ? 161.193 188.972 134.246 1.00 72.83  ? 321 ASN B O   1 
ATOM   5325  C CB  . ASN B 2 305 ? 160.490 188.812 137.350 1.00 69.76  ? 321 ASN B CB  1 
ATOM   5326  C CG  . ASN B 2 305 ? 159.661 189.899 136.696 1.00 68.81  ? 321 ASN B CG  1 
ATOM   5327  O OD1 . ASN B 2 305 ? 158.781 189.619 135.883 1.00 67.12  ? 321 ASN B OD1 1 
ATOM   5328  N ND2 . ASN B 2 305 ? 159.935 191.147 137.053 1.00 68.61  ? 321 ASN B ND2 1 
ATOM   5329  N N   . ALA B 2 306 ? 163.127 188.660 135.357 1.00 75.84  ? 322 ALA B N   1 
ATOM   5330  C CA  . ALA B 2 306 ? 163.914 189.328 134.326 1.00 78.98  ? 322 ALA B CA  1 
ATOM   5331  C C   . ALA B 2 306 ? 164.049 188.462 133.078 1.00 76.84  ? 322 ALA B C   1 
ATOM   5332  O O   . ALA B 2 306 ? 163.887 188.948 131.953 1.00 75.31  ? 322 ALA B O   1 
ATOM   5333  C CB  . ALA B 2 306 ? 165.291 189.695 134.879 1.00 77.58  ? 322 ALA B CB  1 
ATOM   5334  N N   . THR B 2 307 ? 164.346 187.173 133.256 1.00 76.36  ? 323 THR B N   1 
ATOM   5335  C CA  . THR B 2 307 ? 164.651 186.315 132.115 1.00 79.45  ? 323 THR B CA  1 
ATOM   5336  C C   . THR B 2 307 ? 163.406 185.887 131.345 1.00 78.58  ? 323 THR B C   1 
ATOM   5337  O O   . THR B 2 307 ? 163.488 185.674 130.129 1.00 73.84  ? 323 THR B O   1 
ATOM   5338  C CB  . THR B 2 307 ? 165.439 185.083 132.575 1.00 80.95  ? 323 THR B CB  1 
ATOM   5339  O OG1 . THR B 2 307 ? 165.871 184.335 131.431 1.00 83.53  ? 323 THR B OG1 1 
ATOM   5340  C CG2 . THR B 2 307 ? 164.596 184.192 133.476 1.00 71.72  ? 323 THR B CG2 1 
ATOM   5341  N N   . VAL B 2 308 ? 162.258 185.774 132.018 1.00 77.95  ? 324 VAL B N   1 
ATOM   5342  C CA  . VAL B 2 308 ? 161.023 185.272 131.418 1.00 76.78  ? 324 VAL B CA  1 
ATOM   5343  C C   . VAL B 2 308 ? 161.300 183.942 130.727 1.00 73.43  ? 324 VAL B C   1 
ATOM   5344  O O   . VAL B 2 308 ? 161.099 183.801 129.516 1.00 72.32  ? 324 VAL B O   1 
ATOM   5345  C CB  . VAL B 2 308 ? 160.411 186.293 130.439 1.00 78.42  ? 324 VAL B CB  1 
ATOM   5346  C CG1 . VAL B 2 308 ? 158.941 185.977 130.188 1.00 65.47  ? 324 VAL B CG1 1 
ATOM   5347  C CG2 . VAL B 2 308 ? 160.564 187.709 130.978 1.00 79.14  ? 324 VAL B CG2 1 
ATOM   5348  N N   . ASP B 2 309 ? 161.771 182.963 131.493 1.00 73.16  ? 325 ASP B N   1 
ATOM   5349  C CA  . ASP B 2 309 ? 162.113 181.647 130.970 1.00 66.85  ? 325 ASP B CA  1 
ATOM   5350  C C   . ASP B 2 309 ? 161.968 180.633 132.098 1.00 57.49  ? 325 ASP B C   1 
ATOM   5351  O O   . ASP B 2 309 ? 161.408 180.933 133.156 1.00 56.55  ? 325 ASP B O   1 
ATOM   5352  C CB  . ASP B 2 309 ? 163.528 181.645 130.379 1.00 69.92  ? 325 ASP B CB  1 
ATOM   5353  C CG  . ASP B 2 309 ? 163.554 182.070 128.926 1.00 78.92  ? 325 ASP B CG  1 
ATOM   5354  O OD1 . ASP B 2 309 ? 162.640 181.670 128.174 1.00 81.79  ? 325 ASP B OD1 1 
ATOM   5355  O OD2 . ASP B 2 309 ? 164.487 182.802 128.537 1.00 77.81  ? 325 ASP B OD2 1 
ATOM   5356  N N   . TRP B 2 310 ? 162.479 179.426 131.869 1.00 49.11  ? 326 TRP B N   1 
ATOM   5357  C CA  . TRP B 2 310 ? 162.461 178.377 132.885 1.00 39.46  ? 326 TRP B CA  1 
ATOM   5358  C C   . TRP B 2 310 ? 163.698 177.516 132.683 1.00 38.00  ? 326 TRP B C   1 
ATOM   5359  O O   . TRP B 2 310 ? 163.813 176.827 131.666 1.00 44.39  ? 326 TRP B O   1 
ATOM   5360  C CB  . TRP B 2 310 ? 161.188 177.539 132.794 1.00 36.13  ? 326 TRP B CB  1 
ATOM   5361  C CG  . TRP B 2 310 ? 159.960 178.246 133.282 1.00 41.97  ? 326 TRP B CG  1 
ATOM   5362  C CD1 . TRP B 2 310 ? 159.050 178.923 132.525 1.00 43.80  ? 326 TRP B CD1 1 
ATOM   5363  C CD2 . TRP B 2 310 ? 159.503 178.340 134.636 1.00 42.99  ? 326 TRP B CD2 1 
ATOM   5364  N NE1 . TRP B 2 310 ? 158.057 179.435 133.322 1.00 43.54  ? 326 TRP B NE1 1 
ATOM   5365  C CE2 . TRP B 2 310 ? 158.312 179.091 134.623 1.00 41.60  ? 326 TRP B CE2 1 
ATOM   5366  C CE3 . TRP B 2 310 ? 159.985 177.864 135.858 1.00 38.54  ? 326 TRP B CE3 1 
ATOM   5367  C CZ2 . TRP B 2 310 ? 157.599 179.378 135.783 1.00 37.48  ? 326 TRP B CZ2 1 
ATOM   5368  C CZ3 . TRP B 2 310 ? 159.274 178.148 137.007 1.00 33.27  ? 326 TRP B CZ3 1 
ATOM   5369  C CH2 . TRP B 2 310 ? 158.096 178.898 136.962 1.00 34.20  ? 326 TRP B CH2 1 
ATOM   5370  N N   . GLU B 2 311 ? 164.619 177.559 133.640 1.00 34.78  ? 327 GLU B N   1 
ATOM   5371  C CA  . GLU B 2 311 ? 165.832 176.753 133.600 1.00 32.79  ? 327 GLU B CA  1 
ATOM   5372  C C   . GLU B 2 311 ? 165.628 175.496 134.431 1.00 25.65  ? 327 GLU B C   1 
ATOM   5373  O O   . GLU B 2 311 ? 165.216 175.575 135.591 1.00 26.57  ? 327 GLU B O   1 
ATOM   5374  C CB  . GLU B 2 311 ? 167.032 177.538 134.128 1.00 35.87  ? 327 GLU B CB  1 
ATOM   5375  C CG  . GLU B 2 311 ? 167.155 178.941 133.575 1.00 43.29  ? 327 GLU B CG  1 
ATOM   5376  C CD  . GLU B 2 311 ? 168.102 179.798 134.389 1.00 54.06  ? 327 GLU B CD  1 
ATOM   5377  O OE1 . GLU B 2 311 ? 168.836 179.237 135.229 1.00 50.94  ? 327 GLU B OE1 1 
ATOM   5378  O OE2 . GLU B 2 311 ? 168.113 181.031 134.190 1.00 57.82  ? 327 GLU B OE2 1 
ATOM   5379  N N   . TRP B 2 312 ? 165.920 174.342 133.839 1.00 22.71  ? 328 TRP B N   1 
ATOM   5380  C CA  . TRP B 2 312 ? 165.755 173.079 134.541 1.00 20.42  ? 328 TRP B CA  1 
ATOM   5381  C C   . TRP B 2 312 ? 166.893 172.868 135.530 1.00 19.29  ? 328 TRP B C   1 
ATOM   5382  O O   . TRP B 2 312 ? 168.055 173.166 135.240 1.00 21.70  ? 328 TRP B O   1 
ATOM   5383  C CB  . TRP B 2 312 ? 165.677 171.917 133.549 1.00 19.13  ? 328 TRP B CB  1 
ATOM   5384  C CG  . TRP B 2 312 ? 166.972 171.560 132.888 1.00 19.46  ? 328 TRP B CG  1 
ATOM   5385  C CD1 . TRP B 2 312 ? 167.559 172.200 131.839 1.00 22.09  ? 328 TRP B CD1 1 
ATOM   5386  C CD2 . TRP B 2 312 ? 167.832 170.465 133.221 1.00 19.98  ? 328 TRP B CD2 1 
ATOM   5387  N NE1 . TRP B 2 312 ? 168.735 171.579 131.503 1.00 21.99  ? 328 TRP B NE1 1 
ATOM   5388  C CE2 . TRP B 2 312 ? 168.925 170.510 132.337 1.00 19.32  ? 328 TRP B CE2 1 
ATOM   5389  C CE3 . TRP B 2 312 ? 167.786 169.454 134.184 1.00 16.62  ? 328 TRP B CE3 1 
ATOM   5390  C CZ2 . TRP B 2 312 ? 169.960 169.585 132.388 1.00 19.15  ? 328 TRP B CZ2 1 
ATOM   5391  C CZ3 . TRP B 2 312 ? 168.814 168.541 134.233 1.00 14.37  ? 328 TRP B CZ3 1 
ATOM   5392  C CH2 . TRP B 2 312 ? 169.886 168.610 133.341 1.00 17.41  ? 328 TRP B CH2 1 
ATOM   5393  N N   . CYS B 2 313 ? 166.547 172.366 136.709 1.00 17.02  ? 329 CYS B N   1 
ATOM   5394  C CA  . CYS B 2 313 ? 167.490 172.110 137.784 1.00 16.47  ? 329 CYS B CA  1 
ATOM   5395  C C   . CYS B 2 313 ? 167.666 170.606 137.964 1.00 15.78  ? 329 CYS B C   1 
ATOM   5396  O O   . CYS B 2 313 ? 167.114 169.797 137.215 1.00 17.68  ? 329 CYS B O   1 
ATOM   5397  C CB  . CYS B 2 313 ? 167.015 172.771 139.081 1.00 18.10  ? 329 CYS B CB  1 
ATOM   5398  S SG  . CYS B 2 313 ? 166.824 174.562 138.985 1.00 23.73  ? 329 CYS B SG  1 
ATOM   5399  N N   . ALA B 2 314 ? 168.445 170.237 138.972 1.00 17.52  ? 330 ALA B N   1 
ATOM   5400  C CA  . ALA B 2 314 ? 168.677 168.829 139.245 1.00 15.21  ? 330 ALA B CA  1 
ATOM   5401  C C   . ALA B 2 314 ? 167.373 168.156 139.669 1.00 18.03  ? 330 ALA B C   1 
ATOM   5402  O O   . ALA B 2 314 ? 166.564 168.763 140.380 1.00 19.46  ? 330 ALA B O   1 
ATOM   5403  C CB  . ALA B 2 314 ? 169.737 168.663 140.334 1.00 12.19  ? 330 ALA B CB  1 
ATOM   5404  N N   . PRO B 2 315 ? 167.130 166.918 139.247 1.00 19.31  ? 331 PRO B N   1 
ATOM   5405  C CA  . PRO B 2 315 ? 165.898 166.232 139.643 1.00 16.40  ? 331 PRO B CA  1 
ATOM   5406  C C   . PRO B 2 315 ? 165.941 165.783 141.096 1.00 18.99  ? 331 PRO B C   1 
ATOM   5407  O O   . PRO B 2 315 ? 167.002 165.581 141.689 1.00 19.69  ? 331 PRO B O   1 
ATOM   5408  C CB  . PRO B 2 315 ? 165.840 165.034 138.693 1.00 15.79  ? 331 PRO B CB  1 
ATOM   5409  C CG  . PRO B 2 315 ? 167.255 164.774 138.352 1.00 16.03  ? 331 PRO B CG  1 
ATOM   5410  C CD  . PRO B 2 315 ? 167.940 166.106 138.324 1.00 16.62  ? 331 PRO B CD  1 
ATOM   5411  N N   . LEU B 2 316 ? 164.751 165.624 141.664 1.00 17.77  ? 332 LEU B N   1 
ATOM   5412  C CA  . LEU B 2 316 ? 164.629 165.205 143.051 1.00 14.97  ? 332 LEU B CA  1 
ATOM   5413  C C   . LEU B 2 316 ? 165.144 163.775 143.211 1.00 19.45  ? 332 LEU B C   1 
ATOM   5414  O O   . LEU B 2 316 ? 164.927 162.936 142.331 1.00 24.00  ? 332 LEU B O   1 
ATOM   5415  C CB  . LEU B 2 316 ? 163.171 165.280 143.501 1.00 18.24  ? 332 LEU B CB  1 
ATOM   5416  C CG  . LEU B 2 316 ? 162.568 166.564 144.083 1.00 15.74  ? 332 LEU B CG  1 
ATOM   5417  C CD1 . LEU B 2 316 ? 162.930 166.729 145.537 1.00 16.30  ? 332 LEU B CD1 1 
ATOM   5418  C CD2 . LEU B 2 316 ? 162.961 167.794 143.282 1.00 14.95  ? 332 LEU B CD2 1 
ATOM   5419  N N   . PRO B 2 317 ? 165.836 163.468 144.311 1.00 22.30  ? 333 PRO B N   1 
ATOM   5420  C CA  . PRO B 2 317 ? 166.271 162.080 144.540 1.00 20.18  ? 333 PRO B CA  1 
ATOM   5421  C C   . PRO B 2 317 ? 165.126 161.103 144.728 1.00 23.70  ? 333 PRO B C   1 
ATOM   5422  O O   . PRO B 2 317 ? 165.333 159.894 144.571 1.00 25.83  ? 333 PRO B O   1 
ATOM   5423  C CB  . PRO B 2 317 ? 167.124 162.187 145.810 1.00 20.87  ? 333 PRO B CB  1 
ATOM   5424  C CG  . PRO B 2 317 ? 167.549 163.605 145.863 1.00 22.82  ? 333 PRO B CG  1 
ATOM   5425  C CD  . PRO B 2 317 ? 166.404 164.389 145.305 1.00 22.82  ? 333 PRO B CD  1 
ATOM   5426  N N   . ARG B 2 318 ? 163.932 161.579 145.073 1.00 24.94  ? 334 ARG B N   1 
ATOM   5427  C CA  . ARG B 2 318 ? 162.764 160.727 145.231 1.00 23.33  ? 334 ARG B CA  1 
ATOM   5428  C C   . ARG B 2 318 ? 161.537 161.472 144.732 1.00 25.84  ? 334 ARG B C   1 
ATOM   5429  O O   . ARG B 2 318 ? 161.491 162.703 144.754 1.00 30.73  ? 334 ARG B O   1 
ATOM   5430  C CB  . ARG B 2 318 ? 162.562 160.308 146.689 1.00 26.87  ? 334 ARG B CB  1 
ATOM   5431  C CG  . ARG B 2 318 ? 163.050 161.326 147.695 1.00 25.09  ? 334 ARG B CG  1 
ATOM   5432  C CD  . ARG B 2 318 ? 162.986 160.769 149.101 1.00 29.51  ? 334 ARG B CD  1 
ATOM   5433  N NE  . ARG B 2 318 ? 164.154 159.960 149.427 1.00 32.98  ? 334 ARG B NE  1 
ATOM   5434  C CZ  . ARG B 2 318 ? 164.149 158.954 150.290 1.00 32.55  ? 334 ARG B CZ  1 
ATOM   5435  N NH1 . ARG B 2 318 ? 163.047 158.597 150.928 1.00 33.54  ? 334 ARG B NH1 1 
ATOM   5436  N NH2 . ARG B 2 318 ? 165.277 158.289 150.519 1.00 27.31  ? 334 ARG B NH2 1 
ATOM   5437  N N   . ASP B 2 319 ? 160.539 160.717 144.285 1.00 25.12  ? 335 ASP B N   1 
ATOM   5438  C CA  . ASP B 2 319 ? 159.296 161.293 143.789 1.00 29.35  ? 335 ASP B CA  1 
ATOM   5439  C C   . ASP B 2 319 ? 158.201 161.102 144.832 1.00 33.03  ? 335 ASP B C   1 
ATOM   5440  O O   . ASP B 2 319 ? 157.859 159.968 145.183 1.00 32.18  ? 335 ASP B O   1 
ATOM   5441  C CB  . ASP B 2 319 ? 158.894 160.678 142.448 1.00 27.82  ? 335 ASP B CB  1 
ATOM   5442  C CG  . ASP B 2 319 ? 159.420 159.278 142.261 1.00 25.53  ? 335 ASP B CG  1 
ATOM   5443  O OD1 . ASP B 2 319 ? 159.007 158.385 143.023 1.00 29.69  ? 335 ASP B OD1 1 
ATOM   5444  O OD2 . ASP B 2 319 ? 160.239 159.068 141.343 1.00 19.98  ? 335 ASP B OD2 1 
ATOM   5445  N N   . ARG B 2 320 ? 157.659 162.216 145.320 1.00 34.35  ? 336 ARG B N   1 
ATOM   5446  C CA  . ARG B 2 320 ? 156.639 162.219 146.356 1.00 30.71  ? 336 ARG B CA  1 
ATOM   5447  C C   . ARG B 2 320 ? 155.597 163.272 146.015 1.00 30.70  ? 336 ARG B C   1 
ATOM   5448  O O   . ARG B 2 320 ? 155.849 164.195 145.239 1.00 32.61  ? 336 ARG B O   1 
ATOM   5449  C CB  . ARG B 2 320 ? 157.232 162.505 147.742 1.00 27.45  ? 336 ARG B CB  1 
ATOM   5450  C CG  . ARG B 2 320 ? 157.999 161.349 148.348 1.00 27.04  ? 336 ARG B CG  1 
ATOM   5451  C CD  . ARG B 2 320 ? 158.929 161.827 149.448 1.00 28.30  ? 336 ARG B CD  1 
ATOM   5452  N NE  . ARG B 2 320 ? 159.514 163.128 149.147 1.00 25.94  ? 336 ARG B NE  1 
ATOM   5453  C CZ  . ARG B 2 320 ? 160.265 163.825 149.989 1.00 23.92  ? 336 ARG B CZ  1 
ATOM   5454  N NH1 . ARG B 2 320 ? 160.543 163.376 151.201 1.00 20.74  ? 336 ARG B NH1 1 
ATOM   5455  N NH2 . ARG B 2 320 ? 160.749 165.001 149.605 1.00 21.32  ? 336 ARG B NH2 1 
ATOM   5456  N N   . LEU B 2 321 ? 154.417 163.124 146.606 1.00 29.55  ? 337 LEU B N   1 
ATOM   5457  C CA  . LEU B 2 321 ? 153.321 164.060 146.415 1.00 29.19  ? 337 LEU B CA  1 
ATOM   5458  C C   . LEU B 2 321 ? 153.017 164.771 147.726 1.00 29.91  ? 337 LEU B C   1 
ATOM   5459  O O   . LEU B 2 321 ? 153.088 164.167 148.800 1.00 32.33  ? 337 LEU B O   1 
ATOM   5460  C CB  . LEU B 2 321 ? 152.068 163.344 145.904 1.00 30.21  ? 337 LEU B CB  1 
ATOM   5461  C CG  . LEU B 2 321 ? 152.107 162.819 144.467 1.00 26.80  ? 337 LEU B CG  1 
ATOM   5462  C CD1 . LEU B 2 321 ? 150.879 161.977 144.178 1.00 26.30  ? 337 LEU B CD1 1 
ATOM   5463  C CD2 . LEU B 2 321 ? 152.219 163.957 143.472 1.00 24.16  ? 337 LEU B CD2 1 
ATOM   5464  N N   . GLN B 2 322 ? 152.694 166.061 147.626 1.00 28.59  ? 338 GLN B N   1 
ATOM   5465  C CA  . GLN B 2 322 ? 152.314 166.885 148.777 1.00 29.60  ? 338 GLN B CA  1 
ATOM   5466  C C   . GLN B 2 322 ? 153.460 167.027 149.776 1.00 28.94  ? 338 GLN B C   1 
ATOM   5467  O O   . GLN B 2 322 ? 153.249 167.044 150.990 1.00 28.59  ? 338 GLN B O   1 
ATOM   5468  C CB  . GLN B 2 322 ? 151.062 166.338 149.465 1.00 30.83  ? 338 GLN B CB  1 
ATOM   5469  C CG  . GLN B 2 322 ? 149.783 166.544 148.680 1.00 30.65  ? 338 GLN B CG  1 
ATOM   5470  C CD  . GLN B 2 322 ? 148.784 165.431 148.902 1.00 41.30  ? 338 GLN B CD  1 
ATOM   5471  O OE1 . GLN B 2 322 ? 148.217 165.298 149.985 1.00 41.35  ? 338 GLN B OE1 1 
ATOM   5472  N NE2 . GLN B 2 322 ? 148.564 164.620 147.874 1.00 45.35  ? 338 GLN B NE2 1 
ATOM   5473  N N   . HIS B 2 323 ? 154.682 167.135 149.267 1.00 28.93  ? 339 HIS B N   1 
ATOM   5474  C CA  . HIS B 2 323 ? 155.824 167.437 150.114 1.00 24.89  ? 339 HIS B CA  1 
ATOM   5475  C C   . HIS B 2 323 ? 155.938 168.945 150.315 1.00 25.15  ? 339 HIS B C   1 
ATOM   5476  O O   . HIS B 2 323 ? 155.331 169.740 149.594 1.00 26.55  ? 339 HIS B O   1 
ATOM   5477  C CB  . HIS B 2 323 ? 157.115 166.872 149.518 1.00 21.49  ? 339 HIS B CB  1 
ATOM   5478  C CG  . HIS B 2 323 ? 157.447 167.409 148.161 1.00 22.58  ? 339 HIS B CG  1 
ATOM   5479  N ND1 . HIS B 2 323 ? 156.736 167.068 147.031 1.00 25.17  ? 339 HIS B ND1 1 
ATOM   5480  C CD2 . HIS B 2 323 ? 158.418 168.258 147.752 1.00 21.76  ? 339 HIS B CD2 1 
ATOM   5481  C CE1 . HIS B 2 323 ? 157.253 167.687 145.986 1.00 23.21  ? 339 HIS B CE1 1 
ATOM   5482  N NE2 . HIS B 2 323 ? 158.274 168.416 146.396 1.00 19.76  ? 339 HIS B NE2 1 
ATOM   5483  N N   . THR B 2 324 ? 156.723 169.333 151.315 1.00 23.97  ? 340 THR B N   1 
ATOM   5484  C CA  . THR B 2 324 ? 156.842 170.727 151.722 1.00 23.89  ? 340 THR B CA  1 
ATOM   5485  C C   . THR B 2 324 ? 158.172 171.287 151.236 1.00 21.90  ? 340 THR B C   1 
ATOM   5486  O O   . THR B 2 324 ? 159.230 170.728 151.537 1.00 23.97  ? 340 THR B O   1 
ATOM   5487  C CB  . THR B 2 324 ? 156.729 170.861 153.241 1.00 25.59  ? 340 THR B CB  1 
ATOM   5488  O OG1 . THR B 2 324 ? 155.769 169.921 153.735 1.00 26.21  ? 340 THR B OG1 1 
ATOM   5489  C CG2 . THR B 2 324 ? 156.292 172.261 153.624 1.00 21.88  ? 340 THR B CG2 1 
ATOM   5490  N N   . LEU B 2 325 ? 158.116 172.388 150.494 1.00 22.34  ? 341 LEU B N   1 
ATOM   5491  C CA  . LEU B 2 325 ? 159.306 173.091 150.032 1.00 19.81  ? 341 LEU B CA  1 
ATOM   5492  C C   . LEU B 2 325 ? 159.499 174.341 150.880 1.00 20.08  ? 341 LEU B C   1 
ATOM   5493  O O   . LEU B 2 325 ? 158.643 175.230 150.885 1.00 21.58  ? 341 LEU B O   1 
ATOM   5494  C CB  . LEU B 2 325 ? 159.185 173.461 148.555 1.00 20.57  ? 341 LEU B CB  1 
ATOM   5495  C CG  . LEU B 2 325 ? 159.626 172.431 147.518 1.00 21.13  ? 341 LEU B CG  1 
ATOM   5496  C CD1 . LEU B 2 325 ? 159.600 173.043 146.131 1.00 19.96  ? 341 LEU B CD1 1 
ATOM   5497  C CD2 . LEU B 2 325 ? 161.008 171.901 147.840 1.00 20.44  ? 341 LEU B CD2 1 
ATOM   5498  N N   . VAL B 2 326 ? 160.622 174.407 151.591 1.00 21.01  ? 342 VAL B N   1 
ATOM   5499  C CA  . VAL B 2 326 ? 160.955 175.531 152.459 1.00 21.88  ? 342 VAL B CA  1 
ATOM   5500  C C   . VAL B 2 326 ? 162.314 176.071 152.040 1.00 20.60  ? 342 VAL B C   1 
ATOM   5501  O O   . VAL B 2 326 ? 163.259 175.300 151.843 1.00 21.22  ? 342 VAL B O   1 
ATOM   5502  C CB  . VAL B 2 326 ? 160.963 175.126 153.945 1.00 20.56  ? 342 VAL B CB  1 
ATOM   5503  C CG1 . VAL B 2 326 ? 161.127 176.351 154.827 1.00 19.48  ? 342 VAL B CG1 1 
ATOM   5504  C CG2 . VAL B 2 326 ? 159.692 174.380 154.303 1.00 20.31  ? 342 VAL B CG2 1 
ATOM   5505  N N   . SER B 2 327 ? 162.409 177.389 151.906 1.00 20.48  ? 343 SER B N   1 
ATOM   5506  C CA  . SER B 2 327 ? 163.642 178.055 151.513 1.00 21.60  ? 343 SER B CA  1 
ATOM   5507  C C   . SER B 2 327 ? 164.353 178.595 152.746 1.00 23.55  ? 343 SER B C   1 
ATOM   5508  O O   . SER B 2 327 ? 163.742 179.281 153.570 1.00 26.43  ? 343 SER B O   1 
ATOM   5509  C CB  . SER B 2 327 ? 163.355 179.192 150.534 1.00 21.70  ? 343 SER B CB  1 
ATOM   5510  O OG  . SER B 2 327 ? 164.391 180.155 150.561 1.00 25.07  ? 343 SER B OG  1 
ATOM   5511  N N   . VAL B 2 328 ? 165.637 178.287 152.864 1.00 21.54  ? 344 VAL B N   1 
ATOM   5512  C CA  . VAL B 2 328 ? 166.468 178.737 153.971 1.00 21.85  ? 344 VAL B CA  1 
ATOM   5513  C C   . VAL B 2 328 ? 167.576 179.616 153.406 1.00 28.19  ? 344 VAL B C   1 
ATOM   5514  O O   . VAL B 2 328 ? 168.615 179.121 152.971 1.00 31.71  ? 344 VAL B O   1 
ATOM   5515  C CB  . VAL B 2 328 ? 167.050 177.550 154.759 1.00 23.79  ? 344 VAL B CB  1 
ATOM   5516  C CG1 . VAL B 2 328 ? 167.812 178.043 155.975 1.00 25.81  ? 344 VAL B CG1 1 
ATOM   5517  C CG2 . VAL B 2 328 ? 165.946 176.596 155.172 1.00 21.72  ? 344 VAL B CG2 1 
ATOM   5518  N N   . PRO B 2 329 ? 167.382 180.938 153.385 1.00 27.95  ? 345 PRO B N   1 
ATOM   5519  C CA  . PRO B 2 329 ? 168.439 181.825 152.876 1.00 26.84  ? 345 PRO B CA  1 
ATOM   5520  C C   . PRO B 2 329 ? 169.687 181.846 153.738 1.00 32.26  ? 345 PRO B C   1 
ATOM   5521  O O   . PRO B 2 329 ? 170.746 182.257 153.249 1.00 36.29  ? 345 PRO B O   1 
ATOM   5522  C CB  . PRO B 2 329 ? 167.761 183.203 152.848 1.00 26.95  ? 345 PRO B CB  1 
ATOM   5523  C CG  . PRO B 2 329 ? 166.296 182.924 152.940 1.00 29.18  ? 345 PRO B CG  1 
ATOM   5524  C CD  . PRO B 2 329 ? 166.175 181.687 153.763 1.00 29.06  ? 345 PRO B CD  1 
ATOM   5525  N N   . GLY B 2 330 ? 169.597 181.428 155.001 1.00 33.81  ? 346 GLY B N   1 
ATOM   5526  C CA  . GLY B 2 330 ? 170.770 181.438 155.859 1.00 33.54  ? 346 GLY B CA  1 
ATOM   5527  C C   . GLY B 2 330 ? 171.866 180.516 155.363 1.00 34.45  ? 346 GLY B C   1 
ATOM   5528  O O   . GLY B 2 330 ? 173.046 180.873 155.383 1.00 39.40  ? 346 GLY B O   1 
ATOM   5529  N N   . LYS B 2 331 ? 171.495 179.319 154.916 1.00 34.91  ? 347 LYS B N   1 
ATOM   5530  C CA  . LYS B 2 331 ? 172.447 178.373 154.355 1.00 37.76  ? 347 LYS B CA  1 
ATOM   5531  C C   . LYS B 2 331 ? 172.367 178.282 152.838 1.00 38.10  ? 347 LYS B C   1 
ATOM   5532  O O   . LYS B 2 331 ? 173.100 177.486 152.242 1.00 38.65  ? 347 LYS B O   1 
ATOM   5533  C CB  . LYS B 2 331 ? 172.237 176.983 154.961 1.00 35.32  ? 347 LYS B CB  1 
ATOM   5534  C CG  . LYS B 2 331 ? 171.022 176.260 154.426 1.00 33.55  ? 347 LYS B CG  1 
ATOM   5535  C CD  . LYS B 2 331 ? 170.804 174.938 155.134 1.00 33.96  ? 347 LYS B CD  1 
ATOM   5536  C CE  . LYS B 2 331 ? 172.109 174.202 155.393 1.00 33.94  ? 347 LYS B CE  1 
ATOM   5537  N NZ  . LYS B 2 331 ? 171.921 172.725 155.400 1.00 28.51  ? 347 LYS B NZ  1 
ATOM   5538  N N   . ASP B 2 332 ? 171.500 179.073 152.202 1.00 35.18  ? 348 ASP B N   1 
ATOM   5539  C CA  . ASP B 2 332 ? 171.325 179.091 150.749 1.00 32.01  ? 348 ASP B CA  1 
ATOM   5540  C C   . ASP B 2 332 ? 170.960 177.691 150.241 1.00 30.39  ? 348 ASP B C   1 
ATOM   5541  O O   . ASP B 2 332 ? 171.712 177.025 149.530 1.00 31.81  ? 348 ASP B O   1 
ATOM   5542  C CB  . ASP B 2 332 ? 172.579 179.657 150.066 1.00 33.81  ? 348 ASP B CB  1 
ATOM   5543  C CG  . ASP B 2 332 ? 172.470 179.687 148.550 1.00 40.47  ? 348 ASP B CG  1 
ATOM   5544  O OD1 . ASP B 2 332 ? 171.967 180.696 148.012 1.00 38.39  ? 348 ASP B OD1 1 
ATOM   5545  O OD2 . ASP B 2 332 ? 172.884 178.710 147.893 1.00 42.64  ? 348 ASP B OD2 1 
ATOM   5546  N N   . ALA B 2 333 ? 169.780 177.247 150.668 1.00 29.74  ? 349 ALA B N   1 
ATOM   5547  C CA  . ALA B 2 333 ? 169.300 175.919 150.322 1.00 26.16  ? 349 ALA B CA  1 
ATOM   5548  C C   . ALA B 2 333 ? 167.780 175.903 150.332 1.00 22.69  ? 349 ALA B C   1 
ATOM   5549  O O   . ALA B 2 333 ? 167.131 176.770 150.921 1.00 23.35  ? 349 ALA B O   1 
ATOM   5550  C CB  . ALA B 2 333 ? 169.848 174.855 151.278 1.00 24.48  ? 349 ALA B CB  1 
ATOM   5551  N N   . ILE B 2 334 ? 167.221 174.899 149.663 1.00 21.75  ? 350 ILE B N   1 
ATOM   5552  C CA  . ILE B 2 334 ? 165.786 174.648 149.635 1.00 18.91  ? 350 ILE B CA  1 
ATOM   5553  C C   . ILE B 2 334 ? 165.550 173.252 150.190 1.00 18.61  ? 350 ILE B C   1 
ATOM   5554  O O   . ILE B 2 334 ? 166.167 172.286 149.729 1.00 18.46  ? 350 ILE B O   1 
ATOM   5555  C CB  . ILE B 2 334 ? 165.212 174.772 148.213 1.00 21.39  ? 350 ILE B CB  1 
ATOM   5556  C CG1 . ILE B 2 334 ? 165.448 176.176 147.660 1.00 20.92  ? 350 ILE B CG1 1 
ATOM   5557  C CG2 . ILE B 2 334 ? 163.733 174.438 148.205 1.00 20.00  ? 350 ILE B CG2 1 
ATOM   5558  C CD1 . ILE B 2 334 ? 164.898 176.372 146.278 1.00 22.38  ? 350 ILE B CD1 1 
ATOM   5559  N N   . TYR B 2 335 ? 164.657 173.146 151.168 1.00 20.21  ? 351 TYR B N   1 
ATOM   5560  C CA  . TYR B 2 335 ? 164.420 171.905 151.888 1.00 18.33  ? 351 TYR B CA  1 
ATOM   5561  C C   . TYR B 2 335 ? 163.114 171.266 151.438 1.00 20.12  ? 351 TYR B C   1 
ATOM   5562  O O   . TYR B 2 335 ? 162.122 171.959 151.200 1.00 23.96  ? 351 TYR B O   1 
ATOM   5563  C CB  . TYR B 2 335 ? 164.381 172.150 153.397 1.00 19.31  ? 351 TYR B CB  1 
ATOM   5564  C CG  . TYR B 2 335 ? 165.740 172.120 154.053 1.00 20.47  ? 351 TYR B CG  1 
ATOM   5565  C CD1 . TYR B 2 335 ? 166.619 173.182 153.918 1.00 18.94  ? 351 TYR B CD1 1 
ATOM   5566  C CD2 . TYR B 2 335 ? 166.143 171.027 154.803 1.00 21.34  ? 351 TYR B CD2 1 
ATOM   5567  C CE1 . TYR B 2 335 ? 167.859 173.158 154.514 1.00 19.00  ? 351 TYR B CE1 1 
ATOM   5568  C CE2 . TYR B 2 335 ? 167.381 170.995 155.402 1.00 20.56  ? 351 TYR B CE2 1 
ATOM   5569  C CZ  . TYR B 2 335 ? 168.235 172.063 155.255 1.00 19.43  ? 351 TYR B CZ  1 
ATOM   5570  O OH  . TYR B 2 335 ? 169.472 172.033 155.853 1.00 25.99  ? 351 TYR B OH  1 
ATOM   5571  N N   . SER B 2 336 ? 163.124 169.941 151.324 1.00 19.74  ? 352 SER B N   1 
ATOM   5572  C CA  . SER B 2 336 ? 161.941 169.159 150.980 1.00 18.15  ? 352 SER B CA  1 
ATOM   5573  C C   . SER B 2 336 ? 161.699 168.155 152.100 1.00 19.21  ? 352 SER B C   1 
ATOM   5574  O O   . SER B 2 336 ? 162.495 167.232 152.295 1.00 17.66  ? 352 SER B O   1 
ATOM   5575  C CB  . SER B 2 336 ? 162.120 168.461 149.635 1.00 19.34  ? 352 SER B CB  1 
ATOM   5576  O OG  . SER B 2 336 ? 160.960 167.733 149.286 1.00 25.28  ? 352 SER B OG  1 
ATOM   5577  N N   . LEU B 2 337 ? 160.603 168.335 152.833 1.00 20.79  ? 353 LEU B N   1 
ATOM   5578  C CA  . LEU B 2 337 ? 160.314 167.558 154.030 1.00 19.26  ? 353 LEU B CA  1 
ATOM   5579  C C   . LEU B 2 337 ? 158.990 166.825 153.877 1.00 18.66  ? 353 LEU B C   1 
ATOM   5580  O O   . LEU B 2 337 ? 158.007 167.394 153.396 1.00 19.43  ? 353 LEU B O   1 
ATOM   5581  C CB  . LEU B 2 337 ? 160.264 168.455 155.274 1.00 18.59  ? 353 LEU B CB  1 
ATOM   5582  C CG  . LEU B 2 337 ? 161.313 169.563 155.387 1.00 19.81  ? 353 LEU B CG  1 
ATOM   5583  C CD1 . LEU B 2 337 ? 160.759 170.892 154.906 1.00 18.02  ? 353 LEU B CD1 1 
ATOM   5584  C CD2 . LEU B 2 337 ? 161.819 169.675 156.811 1.00 20.08  ? 353 LEU B CD2 1 
ATOM   5585  N N   . GLY B 2 338 ? 158.973 165.561 154.292 1.00 18.68  ? 354 GLY B N   1 
ATOM   5586  C CA  . GLY B 2 338 ? 157.755 164.780 154.272 1.00 18.53  ? 354 GLY B CA  1 
ATOM   5587  C C   . GLY B 2 338 ? 157.280 164.490 152.859 1.00 22.24  ? 354 GLY B C   1 
ATOM   5588  O O   . GLY B 2 338 ? 158.031 164.559 151.886 1.00 28.31  ? 354 GLY B O   1 
ATOM   5589  N N   . GLY B 2 339 ? 155.999 164.162 152.759 1.00 21.66  ? 355 GLY B N   1 
ATOM   5590  C CA  . GLY B 2 339 ? 155.364 163.872 151.494 1.00 22.25  ? 355 GLY B CA  1 
ATOM   5591  C C   . GLY B 2 339 ? 154.611 162.563 151.537 1.00 30.88  ? 355 GLY B C   1 
ATOM   5592  O O   . GLY B 2 339 ? 154.529 161.888 152.561 1.00 34.63  ? 355 GLY B O   1 
ATOM   5593  N N   . LYS B 2 340 ? 154.051 162.205 150.385 1.00 33.68  ? 356 LYS B N   1 
ATOM   5594  C CA  . LYS B 2 340 ? 153.297 160.969 150.223 1.00 30.96  ? 356 LYS B CA  1 
ATOM   5595  C C   . LYS B 2 340 ? 153.770 160.277 148.956 1.00 36.64  ? 356 LYS B C   1 
ATOM   5596  O O   . LYS B 2 340 ? 153.720 160.866 147.872 1.00 38.76  ? 356 LYS B O   1 
ATOM   5597  C CB  . LYS B 2 340 ? 151.794 161.248 150.158 1.00 30.67  ? 356 LYS B CB  1 
ATOM   5598  C CG  . LYS B 2 340 ? 150.926 160.007 150.202 1.00 38.27  ? 356 LYS B CG  1 
ATOM   5599  C CD  . LYS B 2 340 ? 149.456 160.364 150.360 1.00 45.89  ? 356 LYS B CD  1 
ATOM   5600  C CE  . LYS B 2 340 ? 149.100 161.634 149.601 1.00 46.19  ? 356 LYS B CE  1 
ATOM   5601  N NZ  . LYS B 2 340 ? 149.182 161.452 148.126 1.00 42.25  ? 356 LYS B NZ  1 
ATOM   5602  N N   . THR B 2 341 ? 154.223 159.035 149.089 1.00 38.12  ? 357 THR B N   1 
ATOM   5603  C CA  . THR B 2 341 ? 154.723 158.294 147.944 1.00 36.15  ? 357 THR B CA  1 
ATOM   5604  C C   . THR B 2 341 ? 153.574 157.904 147.016 1.00 39.79  ? 357 THR B C   1 
ATOM   5605  O O   . THR B 2 341 ? 152.393 158.022 147.354 1.00 42.02  ? 357 THR B O   1 
ATOM   5606  C CB  . THR B 2 341 ? 155.482 157.050 148.398 1.00 34.81  ? 357 THR B CB  1 
ATOM   5607  O OG1 . THR B 2 341 ? 154.559 155.977 148.614 1.00 36.68  ? 357 THR B OG1 1 
ATOM   5608  C CG2 . THR B 2 341 ? 156.228 157.329 149.686 1.00 36.42  ? 357 THR B CG2 1 
ATOM   5609  N N   . LEU B 2 342 ? 153.936 157.433 145.822 1.00 39.23  ? 358 LEU B N   1 
ATOM   5610  C CA  . LEU B 2 342 ? 152.938 157.039 144.836 1.00 39.37  ? 358 LEU B CA  1 
ATOM   5611  C C   . LEU B 2 342 ? 152.212 155.757 145.218 1.00 41.77  ? 358 LEU B C   1 
ATOM   5612  O O   . LEU B 2 342 ? 151.228 155.403 144.560 1.00 43.68  ? 358 LEU B O   1 
ATOM   5613  C CB  . LEU B 2 342 ? 153.587 156.882 143.460 1.00 41.49  ? 358 LEU B CB  1 
ATOM   5614  C CG  . LEU B 2 342 ? 153.535 158.087 142.513 1.00 39.22  ? 358 LEU B CG  1 
ATOM   5615  C CD1 . LEU B 2 342 ? 152.127 158.292 141.976 1.00 34.49  ? 358 LEU B CD1 1 
ATOM   5616  C CD2 . LEU B 2 342 ? 154.048 159.357 143.181 1.00 30.14  ? 358 LEU B CD2 1 
ATOM   5617  N N   . GLN B 2 343 ? 152.672 155.055 146.252 1.00 44.56  ? 359 GLN B N   1 
ATOM   5618  C CA  . GLN B 2 343 ? 151.985 153.889 146.787 1.00 42.42  ? 359 GLN B CA  1 
ATOM   5619  C C   . GLN B 2 343 ? 151.118 154.234 147.992 1.00 50.69  ? 359 GLN B C   1 
ATOM   5620  O O   . GLN B 2 343 ? 150.782 153.344 148.781 1.00 54.79  ? 359 GLN B O   1 
ATOM   5621  C CB  . GLN B 2 343 ? 152.997 152.803 147.152 1.00 39.10  ? 359 GLN B CB  1 
ATOM   5622  C CG  . GLN B 2 343 ? 153.363 151.896 145.992 1.00 41.45  ? 359 GLN B CG  1 
ATOM   5623  C CD  . GLN B 2 343 ? 154.571 152.389 145.223 1.00 40.22  ? 359 GLN B CD  1 
ATOM   5624  O OE1 . GLN B 2 343 ? 155.522 152.909 145.803 1.00 35.93  ? 359 GLN B OE1 1 
ATOM   5625  N NE2 . GLN B 2 343 ? 154.534 152.235 143.905 1.00 36.96  ? 359 GLN B NE2 1 
ATOM   5626  N N   . ASP B 2 344 ? 150.759 155.512 148.149 1.00 48.40  ? 360 ASP B N   1 
ATOM   5627  C CA  . ASP B 2 344 ? 149.895 155.980 149.233 1.00 46.51  ? 360 ASP B CA  1 
ATOM   5628  C C   . ASP B 2 344 ? 150.496 155.665 150.603 1.00 46.73  ? 360 ASP B C   1 
ATOM   5629  O O   . ASP B 2 344 ? 149.853 155.073 151.471 1.00 51.09  ? 360 ASP B O   1 
ATOM   5630  C CB  . ASP B 2 344 ? 148.485 155.397 149.102 1.00 53.23  ? 360 ASP B CB  1 
ATOM   5631  C CG  . ASP B 2 344 ? 147.588 156.235 148.213 1.00 61.90  ? 360 ASP B CG  1 
ATOM   5632  O OD1 . ASP B 2 344 ? 147.454 157.449 148.475 1.00 58.42  ? 360 ASP B OD1 1 
ATOM   5633  O OD2 . ASP B 2 344 ? 147.017 155.683 147.250 1.00 68.91  ? 360 ASP B OD2 1 
ATOM   5634  N N   . THR B 2 345 ? 151.750 156.070 150.793 1.00 42.02  ? 361 THR B N   1 
ATOM   5635  C CA  . THR B 2 345 ? 152.457 155.877 152.051 1.00 42.04  ? 361 THR B CA  1 
ATOM   5636  C C   . THR B 2 345 ? 153.097 157.193 152.466 1.00 38.77  ? 361 THR B C   1 
ATOM   5637  O O   . THR B 2 345 ? 153.773 157.836 151.659 1.00 39.45  ? 361 THR B O   1 
ATOM   5638  C CB  . THR B 2 345 ? 153.520 154.781 151.926 1.00 43.54  ? 361 THR B CB  1 
ATOM   5639  O OG1 . THR B 2 345 ? 152.880 153.502 151.837 1.00 42.53  ? 361 THR B OG1 1 
ATOM   5640  C CG2 . THR B 2 345 ? 154.451 154.790 153.128 1.00 40.38  ? 361 THR B CG2 1 
ATOM   5641  N N   . LEU B 2 346 ? 152.880 157.592 153.715 1.00 40.59  ? 362 LEU B N   1 
ATOM   5642  C CA  . LEU B 2 346 ? 153.457 158.832 154.215 1.00 33.81  ? 362 LEU B CA  1 
ATOM   5643  C C   . LEU B 2 346 ? 154.968 158.699 154.354 1.00 35.74  ? 362 LEU B C   1 
ATOM   5644  O O   . LEU B 2 346 ? 155.484 157.647 154.739 1.00 42.42  ? 362 LEU B O   1 
ATOM   5645  C CB  . LEU B 2 346 ? 152.834 159.204 155.559 1.00 35.90  ? 362 LEU B CB  1 
ATOM   5646  C CG  . LEU B 2 346 ? 151.353 159.586 155.549 1.00 37.90  ? 362 LEU B CG  1 
ATOM   5647  C CD1 . LEU B 2 346 ? 150.991 160.314 156.824 1.00 41.54  ? 362 LEU B CD1 1 
ATOM   5648  C CD2 . LEU B 2 346 ? 151.017 160.433 154.339 1.00 35.28  ? 362 LEU B CD2 1 
ATOM   5649  N N   . SER B 2 347 ? 155.678 159.779 154.044 1.00 31.34  ? 363 SER B N   1 
ATOM   5650  C CA  . SER B 2 347 ? 157.131 159.791 154.041 1.00 28.04  ? 363 SER B CA  1 
ATOM   5651  C C   . SER B 2 347 ? 157.646 160.734 155.118 1.00 27.55  ? 363 SER B C   1 
ATOM   5652  O O   . SER B 2 347 ? 157.002 161.732 155.452 1.00 32.13  ? 363 SER B O   1 
ATOM   5653  C CB  . SER B 2 347 ? 157.677 160.213 152.672 1.00 26.89  ? 363 SER B CB  1 
ATOM   5654  O OG  . SER B 2 347 ? 159.070 160.449 152.727 1.00 27.45  ? 363 SER B OG  1 
ATOM   5655  N N   . ASN B 2 348 ? 158.818 160.404 155.667 1.00 27.38  ? 364 ASN B N   1 
ATOM   5656  C CA  . ASN B 2 348 ? 159.450 161.226 156.693 1.00 27.88  ? 364 ASN B CA  1 
ATOM   5657  C C   . ASN B 2 348 ? 160.867 161.630 156.307 1.00 26.71  ? 364 ASN B C   1 
ATOM   5658  O O   . ASN B 2 348 ? 161.634 162.070 157.166 1.00 29.66  ? 364 ASN B O   1 
ATOM   5659  C CB  . ASN B 2 348 ? 159.457 160.503 158.043 1.00 33.07  ? 364 ASN B CB  1 
ATOM   5660  C CG  . ASN B 2 348 ? 160.262 159.222 158.017 1.00 35.22  ? 364 ASN B CG  1 
ATOM   5661  O OD1 . ASN B 2 348 ? 160.549 158.674 156.955 1.00 35.90  ? 364 ASN B OD1 1 
ATOM   5662  N ND2 . ASN B 2 348 ? 160.628 158.734 159.194 1.00 37.51  ? 364 ASN B ND2 1 
ATOM   5663  N N   . ALA B 2 349 ? 161.230 161.491 155.038 1.00 28.05  ? 365 ALA B N   1 
ATOM   5664  C CA  . ALA B 2 349 ? 162.563 161.855 154.588 1.00 28.45  ? 365 ALA B CA  1 
ATOM   5665  C C   . ALA B 2 349 ? 162.705 163.368 154.489 1.00 27.45  ? 365 ALA B C   1 
ATOM   5666  O O   . ALA B 2 349 ? 161.732 164.094 154.275 1.00 26.26  ? 365 ALA B O   1 
ATOM   5667  C CB  . ALA B 2 349 ? 162.865 161.215 153.234 1.00 28.96  ? 365 ALA B CB  1 
ATOM   5668  N N   . VAL B 2 350 ? 163.938 163.839 154.655 1.00 27.54  ? 366 VAL B N   1 
ATOM   5669  C CA  . VAL B 2 350 ? 164.279 165.246 154.492 1.00 22.98  ? 366 VAL B CA  1 
ATOM   5670  C C   . VAL B 2 350 ? 165.461 165.339 153.539 1.00 23.77  ? 366 VAL B C   1 
ATOM   5671  O O   . VAL B 2 350 ? 166.497 164.706 153.766 1.00 25.26  ? 366 VAL B O   1 
ATOM   5672  C CB  . VAL B 2 350 ? 164.616 165.921 155.835 1.00 23.78  ? 366 VAL B CB  1 
ATOM   5673  C CG1 . VAL B 2 350 ? 165.059 167.358 155.610 1.00 21.88  ? 366 VAL B CG1 1 
ATOM   5674  C CG2 . VAL B 2 350 ? 163.424 165.870 156.768 1.00 23.55  ? 366 VAL B CG2 1 
ATOM   5675  N N   . ILE B 2 351 ? 165.302 166.116 152.473 1.00 22.62  ? 367 ILE B N   1 
ATOM   5676  C CA  . ILE B 2 351 ? 166.360 166.358 151.502 1.00 20.40  ? 367 ILE B CA  1 
ATOM   5677  C C   . ILE B 2 351 ? 166.415 167.850 151.216 1.00 20.43  ? 367 ILE B C   1 
ATOM   5678  O O   . ILE B 2 351 ? 165.381 168.525 151.200 1.00 23.15  ? 367 ILE B O   1 
ATOM   5679  C CB  . ILE B 2 351 ? 166.141 165.556 150.201 1.00 22.68  ? 367 ILE B CB  1 
ATOM   5680  C CG1 . ILE B 2 351 ? 164.758 165.834 149.621 1.00 24.17  ? 367 ILE B CG1 1 
ATOM   5681  C CG2 . ILE B 2 351 ? 166.303 164.071 150.451 1.00 27.40  ? 367 ILE B CG2 1 
ATOM   5682  C CD1 . ILE B 2 351 ? 164.527 165.180 148.291 1.00 21.29  ? 367 ILE B CD1 1 
ATOM   5683  N N   . TYR B 2 352 ? 167.620 168.371 151.005 1.00 20.35  ? 368 TYR B N   1 
ATOM   5684  C CA  . TYR B 2 352 ? 167.792 169.780 150.695 1.00 20.05  ? 368 TYR B CA  1 
ATOM   5685  C C   . TYR B 2 352 ? 168.604 169.943 149.418 1.00 20.27  ? 368 TYR B C   1 
ATOM   5686  O O   . TYR B 2 352 ? 169.360 169.058 149.012 1.00 19.71  ? 368 TYR B O   1 
ATOM   5687  C CB  . TYR B 2 352 ? 168.451 170.551 151.850 1.00 20.76  ? 368 TYR B CB  1 
ATOM   5688  C CG  . TYR B 2 352 ? 169.858 170.130 152.191 1.00 21.22  ? 368 TYR B CG  1 
ATOM   5689  C CD1 . TYR B 2 352 ? 170.099 168.983 152.930 1.00 23.11  ? 368 TYR B CD1 1 
ATOM   5690  C CD2 . TYR B 2 352 ? 170.945 170.891 151.790 1.00 22.02  ? 368 TYR B CD2 1 
ATOM   5691  C CE1 . TYR B 2 352 ? 171.380 168.599 153.251 1.00 27.07  ? 368 TYR B CE1 1 
ATOM   5692  C CE2 . TYR B 2 352 ? 172.230 170.514 152.103 1.00 26.16  ? 368 TYR B CE2 1 
ATOM   5693  C CZ  . TYR B 2 352 ? 172.442 169.368 152.834 1.00 32.60  ? 368 TYR B CZ  1 
ATOM   5694  O OH  . TYR B 2 352 ? 173.723 168.986 153.151 1.00 40.09  ? 368 TYR B OH  1 
ATOM   5695  N N   . TYR B 2 353 ? 168.423 171.098 148.785 1.00 20.34  ? 369 TYR B N   1 
ATOM   5696  C CA  . TYR B 2 353 ? 169.010 171.414 147.490 1.00 18.31  ? 369 TYR B CA  1 
ATOM   5697  C C   . TYR B 2 353 ? 169.903 172.635 147.645 1.00 21.55  ? 369 TYR B C   1 
ATOM   5698  O O   . TYR B 2 353 ? 169.440 173.690 148.088 1.00 23.27  ? 369 TYR B O   1 
ATOM   5699  C CB  . TYR B 2 353 ? 167.909 171.669 146.458 1.00 17.66  ? 369 TYR B CB  1 
ATOM   5700  C CG  . TYR B 2 353 ? 168.372 172.263 145.151 1.00 18.67  ? 369 TYR B CG  1 
ATOM   5701  C CD1 . TYR B 2 353 ? 168.975 171.476 144.183 1.00 19.61  ? 369 TYR B CD1 1 
ATOM   5702  C CD2 . TYR B 2 353 ? 168.181 173.607 144.873 1.00 20.60  ? 369 TYR B CD2 1 
ATOM   5703  C CE1 . TYR B 2 353 ? 169.389 172.014 142.985 1.00 19.40  ? 369 TYR B CE1 1 
ATOM   5704  C CE2 . TYR B 2 353 ? 168.595 174.153 143.679 1.00 21.51  ? 369 TYR B CE2 1 
ATOM   5705  C CZ  . TYR B 2 353 ? 169.198 173.352 142.739 1.00 18.77  ? 369 TYR B CZ  1 
ATOM   5706  O OH  . TYR B 2 353 ? 169.611 173.894 141.546 1.00 19.84  ? 369 TYR B OH  1 
ATOM   5707  N N   . ARG B 2 354 ? 171.173 172.496 147.279 1.00 22.54  ? 370 ARG B N   1 
ATOM   5708  C CA  . ARG B 2 354 ? 172.112 173.608 147.353 1.00 22.63  ? 370 ARG B CA  1 
ATOM   5709  C C   . ARG B 2 354 ? 172.044 174.414 146.063 1.00 26.03  ? 370 ARG B C   1 
ATOM   5710  O O   . ARG B 2 354 ? 172.360 173.901 144.985 1.00 26.15  ? 370 ARG B O   1 
ATOM   5711  C CB  . ARG B 2 354 ? 173.528 173.099 147.604 1.00 30.42  ? 370 ARG B CB  1 
ATOM   5712  C CG  . ARG B 2 354 ? 174.009 173.310 149.028 1.00 40.12  ? 370 ARG B CG  1 
ATOM   5713  C CD  . ARG B 2 354 ? 175.314 172.581 149.293 1.00 42.17  ? 370 ARG B CD  1 
ATOM   5714  N NE  . ARG B 2 354 ? 175.327 171.244 148.711 1.00 47.00  ? 370 ARG B NE  1 
ATOM   5715  C CZ  . ARG B 2 354 ? 176.428 170.551 148.456 1.00 51.08  ? 370 ARG B CZ  1 
ATOM   5716  N NH1 . ARG B 2 354 ? 177.628 171.038 148.721 1.00 49.75  ? 370 ARG B NH1 1 
ATOM   5717  N NH2 . ARG B 2 354 ? 176.322 169.338 147.920 1.00 45.29  ? 370 ARG B NH2 1 
ATOM   5718  N N   . VAL B 2 355 ? 171.630 175.676 146.178 1.00 29.76  ? 371 VAL B N   1 
ATOM   5719  C CA  . VAL B 2 355 ? 171.435 176.514 144.999 1.00 28.60  ? 371 VAL B CA  1 
ATOM   5720  C C   . VAL B 2 355 ? 172.763 176.795 144.309 1.00 31.62  ? 371 VAL B C   1 
ATOM   5721  O O   . VAL B 2 355 ? 172.851 176.790 143.076 1.00 32.72  ? 371 VAL B O   1 
ATOM   5722  C CB  . VAL B 2 355 ? 170.709 177.812 145.395 1.00 26.38  ? 371 VAL B CB  1 
ATOM   5723  C CG1 . VAL B 2 355 ? 170.457 178.676 144.177 1.00 28.48  ? 371 VAL B CG1 1 
ATOM   5724  C CG2 . VAL B 2 355 ? 169.405 177.489 146.106 1.00 22.84  ? 371 VAL B CG2 1 
ATOM   5725  N N   . GLY B 2 356 ? 173.816 177.050 145.087 1.00 32.58  ? 372 GLY B N   1 
ATOM   5726  C CA  . GLY B 2 356 ? 175.111 177.334 144.491 1.00 35.04  ? 372 GLY B CA  1 
ATOM   5727  C C   . GLY B 2 356 ? 175.712 176.139 143.775 1.00 37.60  ? 372 GLY B C   1 
ATOM   5728  O O   . GLY B 2 356 ? 176.362 176.290 142.737 1.00 38.79  ? 372 GLY B O   1 
ATOM   5729  N N   . ASP B 2 357 ? 175.511 174.939 144.319 1.00 37.29  ? 373 ASP B N   1 
ATOM   5730  C CA  . ASP B 2 357 ? 176.105 173.729 143.767 1.00 32.74  ? 373 ASP B CA  1 
ATOM   5731  C C   . ASP B 2 357 ? 175.208 172.999 142.778 1.00 35.11  ? 373 ASP B C   1 
ATOM   5732  O O   . ASP B 2 357 ? 175.723 172.224 141.965 1.00 39.00  ? 373 ASP B O   1 
ATOM   5733  C CB  . ASP B 2 357 ? 176.480 172.761 144.895 1.00 34.69  ? 373 ASP B CB  1 
ATOM   5734  C CG  . ASP B 2 357 ? 177.536 173.326 145.820 1.00 48.85  ? 373 ASP B CG  1 
ATOM   5735  O OD1 . ASP B 2 357 ? 177.171 174.043 146.774 1.00 51.08  ? 373 ASP B OD1 1 
ATOM   5736  O OD2 . ASP B 2 357 ? 178.733 173.053 145.594 1.00 55.06  ? 373 ASP B OD2 1 
ATOM   5737  N N   . ASN B 2 358 ? 173.892 173.220 142.831 1.00 30.09  ? 374 ASN B N   1 
ATOM   5738  C CA  . ASN B 2 358 ? 172.922 172.497 142.004 1.00 24.95  ? 374 ASN B CA  1 
ATOM   5739  C C   . ASN B 2 358 ? 172.963 170.998 142.301 1.00 25.60  ? 374 ASN B C   1 
ATOM   5740  O O   . ASN B 2 358 ? 173.040 170.163 141.399 1.00 27.90  ? 374 ASN B O   1 
ATOM   5741  C CB  . ASN B 2 358 ? 173.147 172.771 140.514 1.00 25.32  ? 374 ASN B CB  1 
ATOM   5742  C CG  . ASN B 2 358 ? 171.924 172.465 139.672 1.00 24.09  ? 374 ASN B CG  1 
ATOM   5743  O OD1 . ASN B 2 358 ? 170.794 172.550 140.145 1.00 24.95  ? 374 ASN B OD1 1 
ATOM   5744  N ND2 . ASN B 2 358 ? 172.148 172.106 138.415 1.00 19.98  ? 374 ASN B ND2 1 
ATOM   5745  N N   . VAL B 2 359 ? 172.911 170.661 143.588 1.00 24.32  ? 375 VAL B N   1 
ATOM   5746  C CA  . VAL B 2 359 ? 173.022 169.281 144.049 1.00 25.40  ? 375 VAL B CA  1 
ATOM   5747  C C   . VAL B 2 359 ? 172.010 169.050 145.164 1.00 22.16  ? 375 VAL B C   1 
ATOM   5748  O O   . VAL B 2 359 ? 171.843 169.895 146.049 1.00 24.71  ? 375 VAL B O   1 
ATOM   5749  C CB  . VAL B 2 359 ? 174.458 168.962 144.527 1.00 27.96  ? 375 VAL B CB  1 
ATOM   5750  C CG1 . VAL B 2 359 ? 174.493 167.677 145.332 1.00 31.22  ? 375 VAL B CG1 1 
ATOM   5751  C CG2 . VAL B 2 359 ? 175.406 168.866 143.344 1.00 28.71  ? 375 VAL B CG2 1 
ATOM   5752  N N   . TRP B 2 360 ? 171.330 167.904 145.118 1.00 20.56  ? 376 TRP B N   1 
ATOM   5753  C CA  . TRP B 2 360 ? 170.430 167.484 146.184 1.00 19.67  ? 376 TRP B CA  1 
ATOM   5754  C C   . TRP B 2 360 ? 171.173 166.587 147.167 1.00 23.74  ? 376 TRP B C   1 
ATOM   5755  O O   . TRP B 2 360 ? 172.020 165.782 146.772 1.00 29.40  ? 376 TRP B O   1 
ATOM   5756  C CB  . TRP B 2 360 ? 169.218 166.741 145.618 1.00 16.95  ? 376 TRP B CB  1 
ATOM   5757  C CG  . TRP B 2 360 ? 168.162 167.626 145.025 1.00 17.94  ? 376 TRP B CG  1 
ATOM   5758  C CD1 . TRP B 2 360 ? 168.046 168.000 143.720 1.00 17.11  ? 376 TRP B CD1 1 
ATOM   5759  C CD2 . TRP B 2 360 ? 167.068 168.240 145.715 1.00 18.32  ? 376 TRP B CD2 1 
ATOM   5760  N NE1 . TRP B 2 360 ? 166.955 168.813 143.556 1.00 14.61  ? 376 TRP B NE1 1 
ATOM   5761  C CE2 . TRP B 2 360 ? 166.336 168.975 144.766 1.00 15.60  ? 376 TRP B CE2 1 
ATOM   5762  C CE3 . TRP B 2 360 ? 166.639 168.243 147.045 1.00 20.12  ? 376 TRP B CE3 1 
ATOM   5763  C CZ2 . TRP B 2 360 ? 165.202 169.707 145.103 1.00 14.42  ? 376 TRP B CZ2 1 
ATOM   5764  C CZ3 . TRP B 2 360 ? 165.510 168.969 147.376 1.00 17.57  ? 376 TRP B CZ3 1 
ATOM   5765  C CH2 . TRP B 2 360 ? 164.806 169.690 146.411 1.00 14.58  ? 376 TRP B CH2 1 
ATOM   5766  N N   . THR B 2 361 ? 170.849 166.731 148.452 1.00 23.84  ? 377 THR B N   1 
ATOM   5767  C CA  . THR B 2 361 ? 171.487 165.960 149.510 1.00 25.00  ? 377 THR B CA  1 
ATOM   5768  C C   . THR B 2 361 ? 170.424 165.491 150.494 1.00 27.42  ? 377 THR B C   1 
ATOM   5769  O O   . THR B 2 361 ? 169.337 166.063 150.576 1.00 29.32  ? 377 THR B O   1 
ATOM   5770  C CB  . THR B 2 361 ? 172.557 166.779 150.245 1.00 27.86  ? 377 THR B CB  1 
ATOM   5771  O OG1 . THR B 2 361 ? 173.160 167.707 149.336 1.00 30.33  ? 377 THR B OG1 1 
ATOM   5772  C CG2 . THR B 2 361 ? 173.635 165.869 150.805 1.00 29.08  ? 377 THR B CG2 1 
ATOM   5773  N N   . GLU B 2 362 ? 170.750 164.442 151.243 1.00 29.06  ? 378 GLU B N   1 
ATOM   5774  C CA  . GLU B 2 362 ? 169.841 163.862 152.223 1.00 29.00  ? 378 GLU B CA  1 
ATOM   5775  C C   . GLU B 2 362 ? 170.252 164.241 153.640 1.00 32.41  ? 378 GLU B C   1 
ATOM   5776  O O   . GLU B 2 362 ? 171.439 164.355 153.956 1.00 37.18  ? 378 GLU B O   1 
ATOM   5777  C CB  . GLU B 2 362 ? 169.796 162.339 152.097 1.00 28.84  ? 378 GLU B CB  1 
ATOM   5778  C CG  . GLU B 2 362 ? 169.309 161.840 150.755 1.00 37.05  ? 378 GLU B CG  1 
ATOM   5779  C CD  . GLU B 2 362 ? 168.008 161.077 150.865 1.00 41.99  ? 378 GLU B CD  1 
ATOM   5780  O OE1 . GLU B 2 362 ? 167.649 160.674 151.991 1.00 35.77  ? 378 GLU B OE1 1 
ATOM   5781  O OE2 . GLU B 2 362 ? 167.343 160.880 149.826 1.00 41.19  ? 378 GLU B OE2 1 
ATOM   5782  N N   . THR B 2 363 ? 169.249 164.427 154.498 1.00 28.03  ? 379 THR B N   1 
ATOM   5783  C CA  . THR B 2 363 ? 169.481 164.779 155.894 1.00 28.66  ? 379 THR B CA  1 
ATOM   5784  C C   . THR B 2 363 ? 168.743 163.818 156.818 1.00 28.48  ? 379 THR B C   1 
ATOM   5785  O O   . THR B 2 363 ? 168.219 162.794 156.368 1.00 29.09  ? 379 THR B O   1 
ATOM   5786  C CB  . THR B 2 363 ? 169.042 166.219 156.171 1.00 33.00  ? 379 THR B CB  1 
ATOM   5787  O OG1 . THR B 2 363 ? 168.960 166.941 154.937 1.00 30.10  ? 379 THR B OG1 1 
ATOM   5788  C CG2 . THR B 2 363 ? 170.041 166.914 157.082 1.00 34.51  ? 379 THR B CG2 1 
ATOM   5789  N N   . THR B 2 364 ? 168.700 164.137 158.108 1.00 29.94  ? 380 THR B N   1 
ATOM   5790  C CA  . THR B 2 364 ? 167.999 163.300 159.071 1.00 32.98  ? 380 THR B CA  1 
ATOM   5791  C C   . THR B 2 364 ? 166.495 163.343 158.829 1.00 30.83  ? 380 THR B C   1 
ATOM   5792  O O   . THR B 2 364 ? 165.947 164.334 158.342 1.00 31.14  ? 380 THR B O   1 
ATOM   5793  C CB  . THR B 2 364 ? 168.314 163.749 160.498 1.00 37.06  ? 380 THR B CB  1 
ATOM   5794  O OG1 . THR B 2 364 ? 167.451 164.830 160.866 1.00 37.74  ? 380 THR B OG1 1 
ATOM   5795  C CG2 . THR B 2 364 ? 169.758 164.210 160.598 1.00 38.74  ? 380 THR B CG2 1 
ATOM   5796  N N   . GLN B 2 365 ? 165.826 162.249 159.178 1.00 33.91  ? 381 GLN B N   1 
ATOM   5797  C CA  . GLN B 2 365 ? 164.410 162.097 158.893 1.00 33.54  ? 381 GLN B CA  1 
ATOM   5798  C C   . GLN B 2 365 ? 163.554 162.726 159.988 1.00 33.16  ? 381 GLN B C   1 
ATOM   5799  O O   . GLN B 2 365 ? 164.012 162.994 161.101 1.00 36.93  ? 381 GLN B O   1 
ATOM   5800  C CB  . GLN B 2 365 ? 164.055 160.618 158.739 1.00 37.58  ? 381 GLN B CB  1 
ATOM   5801  C CG  . GLN B 2 365 ? 165.075 159.825 157.945 1.00 43.08  ? 381 GLN B CG  1 
ATOM   5802  C CD  . GLN B 2 365 ? 164.645 158.394 157.705 1.00 53.46  ? 381 GLN B CD  1 
ATOM   5803  O OE1 . GLN B 2 365 ? 164.335 158.009 156.577 1.00 51.93  ? 381 GLN B OE1 1 
ATOM   5804  N NE2 . GLN B 2 365 ? 164.624 157.596 158.765 1.00 53.20  ? 381 GLN B NE2 1 
ATOM   5805  N N   . LEU B 2 366 ? 162.289 162.961 159.652 1.00 31.52  ? 382 LEU B N   1 
ATOM   5806  C CA  . LEU B 2 366 ? 161.332 163.471 160.622 1.00 32.62  ? 382 LEU B CA  1 
ATOM   5807  C C   . LEU B 2 366 ? 160.956 162.389 161.628 1.00 38.28  ? 382 LEU B C   1 
ATOM   5808  O O   . LEU B 2 366 ? 160.976 161.193 161.327 1.00 40.49  ? 382 LEU B O   1 
ATOM   5809  C CB  . LEU B 2 366 ? 160.073 163.979 159.919 1.00 29.19  ? 382 LEU B CB  1 
ATOM   5810  C CG  . LEU B 2 366 ? 160.240 164.971 158.770 1.00 27.85  ? 382 LEU B CG  1 
ATOM   5811  C CD1 . LEU B 2 366 ? 158.912 165.205 158.075 1.00 25.26  ? 382 LEU B CD1 1 
ATOM   5812  C CD2 . LEU B 2 366 ? 160.814 166.274 159.282 1.00 28.27  ? 382 LEU B CD2 1 
ATOM   5813  N N   . GLU B 2 367 ? 160.612 162.825 162.841 1.00 37.37  ? 383 GLU B N   1 
ATOM   5814  C CA  . GLU B 2 367 ? 160.127 161.887 163.849 1.00 37.46  ? 383 GLU B CA  1 
ATOM   5815  C C   . GLU B 2 367 ? 158.784 161.290 163.452 1.00 38.46  ? 383 GLU B C   1 
ATOM   5816  O O   . GLU B 2 367 ? 158.541 160.097 163.665 1.00 42.91  ? 383 GLU B O   1 
ATOM   5817  C CB  . GLU B 2 367 ? 160.023 162.576 165.207 1.00 39.42  ? 383 GLU B CB  1 
ATOM   5818  C CG  . GLU B 2 367 ? 161.134 163.560 165.495 1.00 42.99  ? 383 GLU B CG  1 
ATOM   5819  C CD  . GLU B 2 367 ? 162.228 162.945 166.340 1.00 52.16  ? 383 GLU B CD  1 
ATOM   5820  O OE1 . GLU B 2 367 ? 162.351 161.703 166.339 1.00 56.23  ? 383 GLU B OE1 1 
ATOM   5821  O OE2 . GLU B 2 367 ? 162.961 163.697 167.013 1.00 51.61  ? 383 GLU B OE2 1 
ATOM   5822  N N   . VAL B 2 368 ? 157.899 162.101 162.880 1.00 35.32  ? 384 VAL B N   1 
ATOM   5823  C CA  . VAL B 2 368 ? 156.573 161.666 162.463 1.00 34.82  ? 384 VAL B CA  1 
ATOM   5824  C C   . VAL B 2 368 ? 156.434 161.931 160.971 1.00 33.57  ? 384 VAL B C   1 
ATOM   5825  O O   . VAL B 2 368 ? 156.732 163.035 160.502 1.00 34.75  ? 384 VAL B O   1 
ATOM   5826  C CB  . VAL B 2 368 ? 155.465 162.383 163.256 1.00 35.75  ? 384 VAL B CB  1 
ATOM   5827  C CG1 . VAL B 2 368 ? 154.095 161.888 162.830 1.00 37.71  ? 384 VAL B CG1 1 
ATOM   5828  C CG2 . VAL B 2 368 ? 155.668 162.184 164.748 1.00 35.09  ? 384 VAL B CG2 1 
ATOM   5829  N N   . ALA B 2 369 ? 155.990 160.920 160.231 1.00 33.37  ? 385 ALA B N   1 
ATOM   5830  C CA  . ALA B 2 369 ? 155.798 161.046 158.793 1.00 31.33  ? 385 ALA B CA  1 
ATOM   5831  C C   . ALA B 2 369 ? 154.456 161.707 158.514 1.00 33.08  ? 385 ALA B C   1 
ATOM   5832  O O   . ALA B 2 369 ? 153.406 161.178 158.892 1.00 37.84  ? 385 ALA B O   1 
ATOM   5833  C CB  . ALA B 2 369 ? 155.874 159.677 158.125 1.00 33.62  ? 385 ALA B CB  1 
ATOM   5834  N N   . VAL B 2 370 ? 154.489 162.862 157.850 1.00 33.26  ? 386 VAL B N   1 
ATOM   5835  C CA  . VAL B 2 370 ? 153.298 163.647 157.561 1.00 33.31  ? 386 VAL B CA  1 
ATOM   5836  C C   . VAL B 2 370 ? 153.309 164.033 156.088 1.00 33.70  ? 386 VAL B C   1 
ATOM   5837  O O   . VAL B 2 370 ? 154.326 163.939 155.402 1.00 34.34  ? 386 VAL B O   1 
ATOM   5838  C CB  . VAL B 2 370 ? 153.197 164.909 158.444 1.00 33.36  ? 386 VAL B CB  1 
ATOM   5839  C CG1 . VAL B 2 370 ? 153.031 164.530 159.906 1.00 36.79  ? 386 VAL B CG1 1 
ATOM   5840  C CG2 . VAL B 2 370 ? 154.422 165.785 158.251 1.00 30.23  ? 386 VAL B CG2 1 
ATOM   5841  N N   . SER B 2 371 ? 152.146 164.465 155.606 1.00 31.15  ? 387 SER B N   1 
ATOM   5842  C CA  . SER B 2 371 ? 152.005 164.989 154.258 1.00 29.41  ? 387 SER B CA  1 
ATOM   5843  C C   . SER B 2 371 ? 151.027 166.153 154.285 1.00 30.74  ? 387 SER B C   1 
ATOM   5844  O O   . SER B 2 371 ? 150.125 166.204 155.122 1.00 34.33  ? 387 SER B O   1 
ATOM   5845  C CB  . SER B 2 371 ? 151.523 163.915 153.274 1.00 31.21  ? 387 SER B CB  1 
ATOM   5846  O OG  . SER B 2 371 ? 150.120 163.969 153.101 1.00 36.62  ? 387 SER B OG  1 
ATOM   5847  N N   . GLY B 2 372 ? 151.216 167.092 153.363 1.00 31.66  ? 388 GLY B N   1 
ATOM   5848  C CA  . GLY B 2 372 ? 150.362 168.257 153.298 1.00 27.65  ? 388 GLY B CA  1 
ATOM   5849  C C   . GLY B 2 372 ? 150.617 169.299 154.361 1.00 27.19  ? 388 GLY B C   1 
ATOM   5850  O O   . GLY B 2 372 ? 149.788 170.198 154.535 1.00 29.54  ? 388 GLY B O   1 
ATOM   5851  N N   . ALA B 2 373 ? 151.733 169.208 155.078 1.00 25.42  ? 389 ALA B N   1 
ATOM   5852  C CA  . ALA B 2 373 ? 152.031 170.161 156.133 1.00 23.37  ? 389 ALA B CA  1 
ATOM   5853  C C   . ALA B 2 373 ? 152.441 171.508 155.546 1.00 27.64  ? 389 ALA B C   1 
ATOM   5854  O O   . ALA B 2 373 ? 152.798 171.627 154.371 1.00 32.97  ? 389 ALA B O   1 
ATOM   5855  C CB  . ALA B 2 373 ? 153.136 169.626 157.041 1.00 20.02  ? 389 ALA B CB  1 
ATOM   5856  N N   . ALA B 2 374 ? 152.381 172.535 156.388 1.00 26.41  ? 390 ALA B N   1 
ATOM   5857  C CA  . ALA B 2 374 ? 152.823 173.874 156.033 1.00 22.69  ? 390 ALA B CA  1 
ATOM   5858  C C   . ALA B 2 374 ? 154.208 174.117 156.611 1.00 23.32  ? 390 ALA B C   1 
ATOM   5859  O O   . ALA B 2 374 ? 154.520 173.662 157.714 1.00 28.19  ? 390 ALA B O   1 
ATOM   5860  C CB  . ALA B 2 374 ? 151.845 174.930 156.546 1.00 24.70  ? 390 ALA B CB  1 
ATOM   5861  N N   . GLY B 2 375 ? 155.037 174.825 155.863 1.00 23.44  ? 391 GLY B N   1 
ATOM   5862  C CA  . GLY B 2 375 ? 156.424 175.049 156.240 1.00 24.51  ? 391 GLY B CA  1 
ATOM   5863  C C   . GLY B 2 375 ? 156.713 176.521 156.451 1.00 27.48  ? 391 GLY B C   1 
ATOM   5864  O O   . GLY B 2 375 ? 156.240 177.368 155.692 1.00 29.35  ? 391 GLY B O   1 
ATOM   5865  N N   . ALA B 2 376 ? 157.493 176.816 157.486 1.00 24.35  ? 392 ALA B N   1 
ATOM   5866  C CA  . ALA B 2 376 ? 157.882 178.178 157.810 1.00 22.61  ? 392 ALA B CA  1 
ATOM   5867  C C   . ALA B 2 376 ? 159.298 178.174 158.360 1.00 22.44  ? 392 ALA B C   1 
ATOM   5868  O O   . ALA B 2 376 ? 159.652 177.317 159.173 1.00 23.75  ? 392 ALA B O   1 
ATOM   5869  C CB  . ALA B 2 376 ? 156.921 178.808 158.823 1.00 24.06  ? 392 ALA B CB  1 
ATOM   5870  N N   . ASN B 2 377 ? 160.101 179.134 157.916 1.00 22.81  ? 393 ASN B N   1 
ATOM   5871  C CA  . ASN B 2 377 ? 161.490 179.265 158.334 1.00 22.63  ? 393 ASN B CA  1 
ATOM   5872  C C   . ASN B 2 377 ? 161.621 180.488 159.231 1.00 24.45  ? 393 ASN B C   1 
ATOM   5873  O O   . ASN B 2 377 ? 161.279 181.602 158.821 1.00 26.60  ? 393 ASN B O   1 
ATOM   5874  C CB  . ASN B 2 377 ? 162.413 179.381 157.121 1.00 20.32  ? 393 ASN B CB  1 
ATOM   5875  C CG  . ASN B 2 377 ? 163.867 179.527 157.505 1.00 20.72  ? 393 ASN B CG  1 
ATOM   5876  O OD1 . ASN B 2 377 ? 164.436 178.662 158.164 1.00 22.80  ? 393 ASN B OD1 1 
ATOM   5877  N ND2 . ASN B 2 377 ? 164.481 180.624 157.085 1.00 21.20  ? 393 ASN B ND2 1 
ATOM   5878  N N   . LEU B 2 378 ? 162.115 180.278 160.449 1.00 21.67  ? 394 LEU B N   1 
ATOM   5879  C CA  . LEU B 2 378 ? 162.322 181.352 161.419 1.00 22.96  ? 394 LEU B CA  1 
ATOM   5880  C C   . LEU B 2 378 ? 163.775 181.316 161.877 1.00 24.42  ? 394 LEU B C   1 
ATOM   5881  O O   . LEU B 2 378 ? 164.121 180.566 162.794 1.00 25.52  ? 394 LEU B O   1 
ATOM   5882  C CB  . LEU B 2 378 ? 161.375 181.220 162.605 1.00 27.46  ? 394 LEU B CB  1 
ATOM   5883  C CG  . LEU B 2 378 ? 160.167 182.154 162.629 1.00 22.19  ? 394 LEU B CG  1 
ATOM   5884  C CD1 . LEU B 2 378 ? 159.160 181.661 163.636 1.00 17.64  ? 394 LEU B CD1 1 
ATOM   5885  C CD2 . LEU B 2 378 ? 160.597 183.570 162.951 1.00 22.61  ? 394 LEU B CD2 1 
ATOM   5886  N N   . ASN B 2 379 ? 164.613 182.137 161.244 1.00 26.47  ? 395 ASN B N   1 
ATOM   5887  C CA  . ASN B 2 379 ? 166.025 182.260 161.605 1.00 27.80  ? 395 ASN B CA  1 
ATOM   5888  C C   . ASN B 2 379 ? 166.728 180.906 161.573 1.00 30.82  ? 395 ASN B C   1 
ATOM   5889  O O   . ASN B 2 379 ? 167.483 180.551 162.480 1.00 35.03  ? 395 ASN B O   1 
ATOM   5890  C CB  . ASN B 2 379 ? 166.185 182.926 162.972 1.00 32.52  ? 395 ASN B CB  1 
ATOM   5891  C CG  . ASN B 2 379 ? 165.394 184.214 163.088 1.00 39.92  ? 395 ASN B CG  1 
ATOM   5892  O OD1 . ASN B 2 379 ? 165.494 185.096 162.235 1.00 46.19  ? 395 ASN B OD1 1 
ATOM   5893  N ND2 . ASN B 2 379 ? 164.601 184.330 164.147 1.00 33.11  ? 395 ASN B ND2 1 
ATOM   5894  N N   . GLY B 2 380 ? 166.477 180.142 160.515 1.00 25.75  ? 396 GLY B N   1 
ATOM   5895  C CA  . GLY B 2 380 ? 167.132 178.864 160.336 1.00 22.61  ? 396 GLY B CA  1 
ATOM   5896  C C   . GLY B 2 380 ? 166.484 177.691 161.030 1.00 23.19  ? 396 GLY B C   1 
ATOM   5897  O O   . GLY B 2 380 ? 167.163 176.693 161.285 1.00 26.19  ? 396 GLY B O   1 
ATOM   5898  N N   . ILE B 2 381 ? 165.200 177.779 161.362 1.00 24.15  ? 397 ILE B N   1 
ATOM   5899  C CA  . ILE B 2 381 ? 164.467 176.678 161.975 1.00 25.40  ? 397 ILE B CA  1 
ATOM   5900  C C   . ILE B 2 381 ? 163.167 176.496 161.209 1.00 24.66  ? 397 ILE B C   1 
ATOM   5901  O O   . ILE B 2 381 ? 162.398 177.451 161.050 1.00 25.94  ? 397 ILE B O   1 
ATOM   5902  C CB  . ILE B 2 381 ? 164.190 176.924 163.467 1.00 26.08  ? 397 ILE B CB  1 
ATOM   5903  C CG1 . ILE B 2 381 ? 165.499 176.893 164.262 1.00 26.90  ? 397 ILE B CG1 1 
ATOM   5904  C CG2 . ILE B 2 381 ? 163.212 175.899 163.992 1.00 21.76  ? 397 ILE B CG2 1 
ATOM   5905  C CD1 . ILE B 2 381 ? 165.339 176.490 165.707 1.00 30.00  ? 397 ILE B CD1 1 
ATOM   5906  N N   . ILE B 2 382 ? 162.919 175.277 160.742 1.00 23.49  ? 398 ILE B N   1 
ATOM   5907  C CA  . ILE B 2 382 ? 161.747 174.959 159.937 1.00 22.29  ? 398 ILE B CA  1 
ATOM   5908  C C   . ILE B 2 382 ? 160.674 174.375 160.843 1.00 24.66  ? 398 ILE B C   1 
ATOM   5909  O O   . ILE B 2 382 ? 160.938 173.442 161.611 1.00 29.36  ? 398 ILE B O   1 
ATOM   5910  C CB  . ILE B 2 382 ? 162.101 173.983 158.802 1.00 22.67  ? 398 ILE B CB  1 
ATOM   5911  C CG1 . ILE B 2 382 ? 163.200 174.574 157.920 1.00 21.21  ? 398 ILE B CG1 1 
ATOM   5912  C CG2 . ILE B 2 382 ? 160.870 173.655 157.975 1.00 22.79  ? 398 ILE B CG2 1 
ATOM   5913  C CD1 . ILE B 2 382 ? 163.850 173.570 157.010 1.00 19.82  ? 398 ILE B CD1 1 
ATOM   5914  N N   . TYR B 2 383 ? 159.466 174.921 160.756 1.00 23.81  ? 399 TYR B N   1 
ATOM   5915  C CA  . TYR B 2 383 ? 158.325 174.457 161.535 1.00 23.26  ? 399 TYR B CA  1 
ATOM   5916  C C   . TYR B 2 383 ? 157.336 173.777 160.600 1.00 26.12  ? 399 TYR B C   1 
ATOM   5917  O O   . TYR B 2 383 ? 156.899 174.375 159.612 1.00 28.62  ? 399 TYR B O   1 
ATOM   5918  C CB  . TYR B 2 383 ? 157.660 175.617 162.276 1.00 25.40  ? 399 TYR B CB  1 
ATOM   5919  C CG  . TYR B 2 383 ? 158.489 176.172 163.410 1.00 25.19  ? 399 TYR B CG  1 
ATOM   5920  C CD1 . TYR B 2 383 ? 158.449 175.596 164.670 1.00 26.99  ? 399 TYR B CD1 1 
ATOM   5921  C CD2 . TYR B 2 383 ? 159.315 177.269 163.219 1.00 22.05  ? 399 TYR B CD2 1 
ATOM   5922  C CE1 . TYR B 2 383 ? 159.207 176.096 165.707 1.00 26.93  ? 399 TYR B CE1 1 
ATOM   5923  C CE2 . TYR B 2 383 ? 160.077 177.776 164.250 1.00 21.96  ? 399 TYR B CE2 1 
ATOM   5924  C CZ  . TYR B 2 383 ? 160.019 177.186 165.491 1.00 25.77  ? 399 TYR B CZ  1 
ATOM   5925  O OH  . TYR B 2 383 ? 160.774 177.686 166.525 1.00 27.37  ? 399 TYR B OH  1 
ATOM   5926  N N   . LEU B 2 384 ? 156.986 172.533 160.913 1.00 24.31  ? 400 LEU B N   1 
ATOM   5927  C CA  . LEU B 2 384 ? 156.023 171.761 160.136 1.00 24.70  ? 400 LEU B CA  1 
ATOM   5928  C C   . LEU B 2 384 ? 154.699 171.770 160.887 1.00 27.72  ? 400 LEU B C   1 
ATOM   5929  O O   . LEU B 2 384 ? 154.590 171.191 161.971 1.00 33.87  ? 400 LEU B O   1 
ATOM   5930  C CB  . LEU B 2 384 ? 156.521 170.336 159.915 1.00 27.98  ? 400 LEU B CB  1 
ATOM   5931  C CG  . LEU B 2 384 ? 157.641 170.169 158.891 1.00 28.05  ? 400 LEU B CG  1 
ATOM   5932  C CD1 . LEU B 2 384 ? 158.687 169.214 159.424 1.00 25.41  ? 400 LEU B CD1 1 
ATOM   5933  C CD2 . LEU B 2 384 ? 157.083 169.678 157.568 1.00 26.40  ? 400 LEU B CD2 1 
ATOM   5934  N N   . LEU B 2 385 ? 153.694 172.418 160.307 1.00 24.83  ? 401 LEU B N   1 
ATOM   5935  C CA  . LEU B 2 385 ? 152.435 172.689 160.987 1.00 25.19  ? 401 LEU B CA  1 
ATOM   5936  C C   . LEU B 2 385 ? 151.311 171.935 160.295 1.00 26.41  ? 401 LEU B C   1 
ATOM   5937  O O   . LEU B 2 385 ? 151.095 172.106 159.091 1.00 27.35  ? 401 LEU B O   1 
ATOM   5938  C CB  . LEU B 2 385 ? 152.146 174.190 161.002 1.00 28.51  ? 401 LEU B CB  1 
ATOM   5939  C CG  . LEU B 2 385 ? 153.317 175.068 161.445 1.00 24.72  ? 401 LEU B CG  1 
ATOM   5940  C CD1 . LEU B 2 385 ? 153.250 176.427 160.781 1.00 23.30  ? 401 LEU B CD1 1 
ATOM   5941  C CD2 . LEU B 2 385 ? 153.334 175.209 162.954 1.00 25.53  ? 401 LEU B CD2 1 
ATOM   5942  N N   . GLY B 2 386 ? 150.593 171.114 161.058 1.00 29.19  ? 402 GLY B N   1 
ATOM   5943  C CA  . GLY B 2 386 ? 149.422 170.444 160.533 1.00 32.37  ? 402 GLY B CA  1 
ATOM   5944  C C   . GLY B 2 386 ? 149.763 169.406 159.479 1.00 31.91  ? 402 GLY B C   1 
ATOM   5945  O O   . GLY B 2 386 ? 150.804 168.746 159.522 1.00 33.78  ? 402 GLY B O   1 
ATOM   5946  N N   . GLY B 2 387 ? 148.854 169.254 158.521 1.00 30.58  ? 403 GLY B N   1 
ATOM   5947  C CA  . GLY B 2 387 ? 149.050 168.311 157.440 1.00 30.39  ? 403 GLY B CA  1 
ATOM   5948  C C   . GLY B 2 387 ? 148.152 167.097 157.527 1.00 35.72  ? 403 GLY B C   1 
ATOM   5949  O O   . GLY B 2 387 ? 146.941 167.221 157.724 1.00 38.61  ? 403 GLY B O   1 
ATOM   5950  N N   . GLU B 2 388 ? 148.738 165.912 157.377 1.00 39.25  ? 404 GLU B N   1 
ATOM   5951  C CA  . GLU B 2 388 ? 147.996 164.659 157.429 1.00 40.95  ? 404 GLU B CA  1 
ATOM   5952  C C   . GLU B 2 388 ? 148.854 163.624 158.135 1.00 42.57  ? 404 GLU B C   1 
ATOM   5953  O O   . GLU B 2 388 ? 149.957 163.315 157.678 1.00 42.97  ? 404 GLU B O   1 
ATOM   5954  C CB  . GLU B 2 388 ? 147.617 164.181 156.025 1.00 42.45  ? 404 GLU B CB  1 
ATOM   5955  C CG  . GLU B 2 388 ? 146.486 163.174 155.996 1.00 53.38  ? 404 GLU B CG  1 
ATOM   5956  C CD  . GLU B 2 388 ? 145.142 163.811 155.698 1.00 64.69  ? 404 GLU B CD  1 
ATOM   5957  O OE1 . GLU B 2 388 ? 145.070 165.057 155.648 1.00 65.62  ? 404 GLU B OE1 1 
ATOM   5958  O OE2 . GLU B 2 388 ? 144.157 163.066 155.515 1.00 65.99  ? 404 GLU B OE2 1 
ATOM   5959  N N   . GLU B 2 389 ? 148.353 163.099 159.246 1.00 47.48  ? 405 GLU B N   1 
ATOM   5960  C CA  . GLU B 2 389 ? 149.062 162.096 160.021 1.00 47.93  ? 405 GLU B CA  1 
ATOM   5961  C C   . GLU B 2 389 ? 148.647 160.696 159.580 1.00 56.69  ? 405 GLU B C   1 
ATOM   5962  O O   . GLU B 2 389 ? 147.700 160.510 158.815 1.00 60.11  ? 405 GLU B O   1 
ATOM   5963  C CB  . GLU B 2 389 ? 148.794 162.290 161.513 1.00 52.48  ? 405 GLU B CB  1 
ATOM   5964  C CG  . GLU B 2 389 ? 149.942 161.882 162.416 1.00 57.06  ? 405 GLU B CG  1 
ATOM   5965  C CD  . GLU B 2 389 ? 149.711 162.274 163.859 1.00 59.16  ? 405 GLU B CD  1 
ATOM   5966  O OE1 . GLU B 2 389 ? 148.674 162.908 164.143 1.00 61.86  ? 405 GLU B OE1 1 
ATOM   5967  O OE2 . GLU B 2 389 ? 150.561 161.941 164.710 1.00 56.73  ? 405 GLU B OE2 1 
ATOM   5968  N N   . ASN B 2 390 ? 149.371 159.699 160.078 1.00 61.33  ? 406 ASN B N   1 
ATOM   5969  C CA  . ASN B 2 390 ? 149.107 158.303 159.747 1.00 64.78  ? 406 ASN B CA  1 
ATOM   5970  C C   . ASN B 2 390 ? 148.165 157.719 160.793 1.00 69.74  ? 406 ASN B C   1 
ATOM   5971  O O   . ASN B 2 390 ? 148.546 157.546 161.955 1.00 68.85  ? 406 ASN B O   1 
ATOM   5972  C CB  . ASN B 2 390 ? 150.410 157.512 159.677 1.00 65.55  ? 406 ASN B CB  1 
ATOM   5973  C CG  . ASN B 2 390 ? 150.253 156.198 158.946 1.00 70.56  ? 406 ASN B CG  1 
ATOM   5974  O OD1 . ASN B 2 390 ? 149.948 156.170 157.754 1.00 72.09  ? 406 ASN B OD1 1 
ATOM   5975  N ND2 . ASN B 2 390 ? 150.459 155.097 159.658 1.00 72.87  ? 406 ASN B ND2 1 
ATOM   5976  N N   . ASP B 2 391 ? 146.936 157.420 160.382 1.00 74.87  ? 407 ASP B N   1 
ATOM   5977  C CA  . ASP B 2 391 ? 145.978 156.792 161.278 1.00 77.90  ? 407 ASP B CA  1 
ATOM   5978  C C   . ASP B 2 391 ? 146.325 155.318 161.475 1.00 85.24  ? 407 ASP B C   1 
ATOM   5979  O O   . ASP B 2 391 ? 146.992 154.691 160.648 1.00 87.77  ? 407 ASP B O   1 
ATOM   5980  C CB  . ASP B 2 391 ? 144.557 156.938 160.733 1.00 80.64  ? 407 ASP B CB  1 
ATOM   5981  C CG  . ASP B 2 391 ? 143.504 156.844 161.819 1.00 82.94  ? 407 ASP B CG  1 
ATOM   5982  O OD1 . ASP B 2 391 ? 143.855 157.001 163.006 1.00 79.58  ? 407 ASP B OD1 1 
ATOM   5983  O OD2 . ASP B 2 391 ? 142.322 156.623 161.484 1.00 87.18  ? 407 ASP B OD2 1 
ATOM   5984  N N   . LEU B 2 392 ? 145.865 154.768 162.601 1.00 91.27  ? 408 LEU B N   1 
ATOM   5985  C CA  . LEU B 2 392 ? 146.248 153.409 162.975 1.00 97.52  ? 408 LEU B CA  1 
ATOM   5986  C C   . LEU B 2 392 ? 145.747 152.381 161.967 1.00 100.26 ? 408 LEU B C   1 
ATOM   5987  O O   . LEU B 2 392 ? 146.492 151.475 161.573 1.00 103.41 ? 408 LEU B O   1 
ATOM   5988  C CB  . LEU B 2 392 ? 145.722 153.085 164.373 1.00 97.60  ? 408 LEU B CB  1 
ATOM   5989  C CG  . LEU B 2 392 ? 146.093 154.075 165.479 1.00 99.64  ? 408 LEU B CG  1 
ATOM   5990  C CD1 . LEU B 2 392 ? 145.602 153.576 166.829 1.00 100.10 ? 408 LEU B CD1 1 
ATOM   5991  C CD2 . LEU B 2 392 ? 147.595 154.315 165.505 1.00 97.80  ? 408 LEU B CD2 1 
ATOM   5992  N N   . ASP B 2 393 ? 144.494 152.505 161.532 1.00 98.96  ? 409 ASP B N   1 
ATOM   5993  C CA  . ASP B 2 393 ? 143.891 151.489 160.676 1.00 104.60 ? 409 ASP B CA  1 
ATOM   5994  C C   . ASP B 2 393 ? 144.245 151.693 159.208 1.00 104.36 ? 409 ASP B C   1 
ATOM   5995  O O   . ASP B 2 393 ? 143.354 151.743 158.354 1.00 104.60 ? 409 ASP B O   1 
ATOM   5996  C CB  . ASP B 2 393 ? 142.371 151.482 160.852 1.00 106.23 ? 409 ASP B CB  1 
ATOM   5997  C CG  . ASP B 2 393 ? 141.755 150.131 160.545 1.00 107.14 ? 409 ASP B CG  1 
ATOM   5998  O OD1 . ASP B 2 393 ? 142.515 149.157 160.359 1.00 105.50 ? 409 ASP B OD1 1 
ATOM   5999  O OD2 . ASP B 2 393 ? 140.511 150.042 160.488 1.00 104.80 ? 409 ASP B OD2 1 
ATOM   6000  N N   . PHE B 2 394 ? 145.540 151.811 158.906 1.00 102.88 ? 410 PHE B N   1 
ATOM   6001  C CA  . PHE B 2 394 ? 146.050 151.932 157.540 1.00 103.94 ? 410 PHE B CA  1 
ATOM   6002  C C   . PHE B 2 394 ? 145.481 153.144 156.804 1.00 101.92 ? 410 PHE B C   1 
ATOM   6003  O O   . PHE B 2 394 ? 145.599 153.243 155.578 1.00 101.26 ? 410 PHE B O   1 
ATOM   6004  C CB  . PHE B 2 394 ? 145.784 150.651 156.738 1.00 105.53 ? 410 PHE B CB  1 
ATOM   6005  C CG  . PHE B 2 394 ? 146.682 150.482 155.545 1.00 111.64 ? 410 PHE B CG  1 
ATOM   6006  C CD1 . PHE B 2 394 ? 148.058 150.451 155.695 1.00 112.34 ? 410 PHE B CD1 1 
ATOM   6007  C CD2 . PHE B 2 394 ? 146.148 150.353 154.273 1.00 114.60 ? 410 PHE B CD2 1 
ATOM   6008  C CE1 . PHE B 2 394 ? 148.886 150.296 154.599 1.00 114.49 ? 410 PHE B CE1 1 
ATOM   6009  C CE2 . PHE B 2 394 ? 146.969 150.198 153.173 1.00 116.74 ? 410 PHE B CE2 1 
ATOM   6010  C CZ  . PHE B 2 394 ? 148.341 150.170 153.336 1.00 118.46 ? 410 PHE B CZ  1 
ATOM   6011  N N   . PHE B 2 395 ? 144.868 154.074 157.527 1.00 98.21  ? 411 PHE B N   1 
ATOM   6012  C CA  . PHE B 2 395 ? 144.281 155.274 156.958 1.00 91.02  ? 411 PHE B CA  1 
ATOM   6013  C C   . PHE B 2 395 ? 145.122 156.486 157.345 1.00 83.35  ? 411 PHE B C   1 
ATOM   6014  O O   . PHE B 2 395 ? 146.198 156.360 157.942 1.00 81.41  ? 411 PHE B O   1 
ATOM   6015  C CB  . PHE B 2 395 ? 142.829 155.425 157.418 1.00 93.60  ? 411 PHE B CB  1 
ATOM   6016  C CG  . PHE B 2 395 ? 141.935 154.298 156.989 1.00 101.71 ? 411 PHE B CG  1 
ATOM   6017  C CD1 . PHE B 2 395 ? 142.006 153.789 155.704 1.00 103.12 ? 411 PHE B CD1 1 
ATOM   6018  C CD2 . PHE B 2 395 ? 141.016 153.753 157.871 1.00 102.14 ? 411 PHE B CD2 1 
ATOM   6019  C CE1 . PHE B 2 395 ? 141.182 152.753 155.307 1.00 103.25 ? 411 PHE B CE1 1 
ATOM   6020  C CE2 . PHE B 2 395 ? 140.189 152.716 157.480 1.00 101.79 ? 411 PHE B CE2 1 
ATOM   6021  C CZ  . PHE B 2 395 ? 140.273 152.216 156.196 1.00 100.26 ? 411 PHE B CZ  1 
ATOM   6022  N N   . THR B 2 396 ? 144.629 157.670 156.997 1.00 78.61  ? 412 THR B N   1 
ATOM   6023  C CA  . THR B 2 396 ? 145.266 158.923 157.364 1.00 71.55  ? 412 THR B CA  1 
ATOM   6024  C C   . THR B 2 396 ? 144.231 159.852 157.980 1.00 68.30  ? 412 THR B C   1 
ATOM   6025  O O   . THR B 2 396 ? 143.057 159.840 157.599 1.00 68.23  ? 412 THR B O   1 
ATOM   6026  C CB  . THR B 2 396 ? 145.926 159.600 156.156 1.00 67.36  ? 412 THR B CB  1 
ATOM   6027  O OG1 . THR B 2 396 ? 145.005 159.630 155.060 1.00 70.05  ? 412 THR B OG1 1 
ATOM   6028  C CG2 . THR B 2 396 ? 147.177 158.846 155.740 1.00 64.85  ? 412 THR B CG2 1 
ATOM   6029  N N   . LYS B 2 397 ? 144.674 160.654 158.937 1.00 62.88  ? 413 LYS B N   1 
ATOM   6030  C CA  . LYS B 2 397 ? 143.822 161.574 159.671 1.00 57.95  ? 413 LYS B CA  1 
ATOM   6031  C C   . LYS B 2 397 ? 144.476 162.944 159.720 1.00 54.31  ? 413 LYS B C   1 
ATOM   6032  O O   . LYS B 2 397 ? 145.697 163.062 159.578 1.00 53.12  ? 413 LYS B O   1 
ATOM   6033  C CB  . LYS B 2 397 ? 143.562 161.069 161.099 1.00 58.84  ? 413 LYS B CB  1 
ATOM   6034  C CG  . LYS B 2 397 ? 144.719 161.287 162.055 1.00 58.38  ? 413 LYS B CG  1 
ATOM   6035  C CD  . LYS B 2 397 ? 144.527 160.509 163.340 1.00 61.70  ? 413 LYS B CD  1 
ATOM   6036  C CE  . LYS B 2 397 ? 145.783 160.541 164.188 1.00 63.74  ? 413 LYS B CE  1 
ATOM   6037  N NZ  . LYS B 2 397 ? 146.628 159.337 163.965 1.00 70.49  ? 413 LYS B NZ  1 
ATOM   6038  N N   . PRO B 2 398 ? 143.687 164.004 159.899 1.00 53.46  ? 414 PRO B N   1 
ATOM   6039  C CA  . PRO B 2 398 ? 144.272 165.345 160.015 1.00 46.66  ? 414 PRO B CA  1 
ATOM   6040  C C   . PRO B 2 398 ? 145.244 165.433 161.182 1.00 44.85  ? 414 PRO B C   1 
ATOM   6041  O O   . PRO B 2 398 ? 145.031 164.840 162.241 1.00 51.67  ? 414 PRO B O   1 
ATOM   6042  C CB  . PRO B 2 398 ? 143.051 166.244 160.232 1.00 44.43  ? 414 PRO B CB  1 
ATOM   6043  C CG  . PRO B 2 398 ? 141.931 165.506 159.600 1.00 47.60  ? 414 PRO B CG  1 
ATOM   6044  C CD  . PRO B 2 398 ? 142.216 164.051 159.823 1.00 52.42  ? 414 PRO B CD  1 
ATOM   6045  N N   . SER B 2 399 ? 146.319 166.186 160.977 1.00 37.74  ? 415 SER B N   1 
ATOM   6046  C CA  . SER B 2 399 ? 147.374 166.346 161.965 1.00 37.62  ? 415 SER B CA  1 
ATOM   6047  C C   . SER B 2 399 ? 147.296 167.735 162.583 1.00 38.16  ? 415 SER B C   1 
ATOM   6048  O O   . SER B 2 399 ? 146.983 168.713 161.899 1.00 36.52  ? 415 SER B O   1 
ATOM   6049  C CB  . SER B 2 399 ? 148.750 166.129 161.334 1.00 40.11  ? 415 SER B CB  1 
ATOM   6050  O OG  . SER B 2 399 ? 149.788 166.323 162.277 1.00 41.63  ? 415 SER B OG  1 
ATOM   6051  N N   . ARG B 2 400 ? 147.574 167.813 163.886 1.00 39.71  ? 416 ARG B N   1 
ATOM   6052  C CA  . ARG B 2 400 ? 147.560 169.083 164.602 1.00 36.11  ? 416 ARG B CA  1 
ATOM   6053  C C   . ARG B 2 400 ? 148.815 169.277 165.442 1.00 36.43  ? 416 ARG B C   1 
ATOM   6054  O O   . ARG B 2 400 ? 148.800 170.063 166.392 1.00 40.14  ? 416 ARG B O   1 
ATOM   6055  C CB  . ARG B 2 400 ? 146.316 169.196 165.485 1.00 39.01  ? 416 ARG B CB  1 
ATOM   6056  C CG  . ARG B 2 400 ? 146.168 168.072 166.491 1.00 40.59  ? 416 ARG B CG  1 
ATOM   6057  C CD  . ARG B 2 400 ? 145.148 168.419 167.561 1.00 42.95  ? 416 ARG B CD  1 
ATOM   6058  N NE  . ARG B 2 400 ? 143.804 168.558 167.013 1.00 47.27  ? 416 ARG B NE  1 
ATOM   6059  C CZ  . ARG B 2 400 ? 143.039 169.629 167.169 1.00 46.95  ? 416 ARG B CZ  1 
ATOM   6060  N NH1 . ARG B 2 400 ? 143.456 170.680 167.855 1.00 47.83  ? 416 ARG B NH1 1 
ATOM   6061  N NH2 . ARG B 2 400 ? 141.826 169.645 166.625 1.00 42.89  ? 416 ARG B NH2 1 
ATOM   6062  N N   . LEU B 2 401 ? 149.899 168.585 165.115 1.00 35.45  ? 417 LEU B N   1 
ATOM   6063  C CA  . LEU B 2 401 ? 151.141 168.705 165.861 1.00 38.69  ? 417 LEU B CA  1 
ATOM   6064  C C   . LEU B 2 401 ? 152.158 169.529 165.082 1.00 39.08  ? 417 LEU B C   1 
ATOM   6065  O O   . LEU B 2 401 ? 152.017 169.766 163.880 1.00 37.72  ? 417 LEU B O   1 
ATOM   6066  C CB  . LEU B 2 401 ? 151.713 167.323 166.193 1.00 38.91  ? 417 LEU B CB  1 
ATOM   6067  C CG  . LEU B 2 401 ? 151.957 166.331 165.057 1.00 41.00  ? 417 LEU B CG  1 
ATOM   6068  C CD1 . LEU B 2 401 ? 153.428 166.282 164.688 1.00 39.58  ? 417 LEU B CD1 1 
ATOM   6069  C CD2 . LEU B 2 401 ? 151.464 164.957 165.460 1.00 44.42  ? 417 LEU B CD2 1 
ATOM   6070  N N   . ILE B 2 402 ? 153.191 169.971 165.793 1.00 35.25  ? 418 ILE B N   1 
ATOM   6071  C CA  . ILE B 2 402 ? 154.227 170.837 165.247 1.00 30.95  ? 418 ILE B CA  1 
ATOM   6072  C C   . ILE B 2 402 ? 155.558 170.109 165.344 1.00 32.05  ? 418 ILE B C   1 
ATOM   6073  O O   . ILE B 2 402 ? 155.901 169.569 166.401 1.00 36.62  ? 418 ILE B O   1 
ATOM   6074  C CB  . ILE B 2 402 ? 154.290 172.186 165.987 1.00 34.99  ? 418 ILE B CB  1 
ATOM   6075  C CG1 . ILE B 2 402 ? 152.902 172.824 166.066 1.00 34.27  ? 418 ILE B CG1 1 
ATOM   6076  C CG2 . ILE B 2 402 ? 155.277 173.123 165.309 1.00 30.67  ? 418 ILE B CG2 1 
ATOM   6077  C CD1 . ILE B 2 402 ? 152.499 173.234 167.459 1.00 29.11  ? 418 ILE B CD1 1 
ATOM   6078  N N   . GLN B 2 403 ? 156.300 170.090 164.241 1.00 31.45  ? 419 GLN B N   1 
ATOM   6079  C CA  . GLN B 2 403 ? 157.629 169.500 164.189 1.00 29.27  ? 419 GLN B CA  1 
ATOM   6080  C C   . GLN B 2 403 ? 158.651 170.596 163.936 1.00 31.00  ? 419 GLN B C   1 
ATOM   6081  O O   . GLN B 2 403 ? 158.402 171.525 163.164 1.00 34.51  ? 419 GLN B O   1 
ATOM   6082  C CB  . GLN B 2 403 ? 157.726 168.430 163.103 1.00 32.77  ? 419 GLN B CB  1 
ATOM   6083  C CG  . GLN B 2 403 ? 156.769 167.270 163.290 1.00 30.83  ? 419 GLN B CG  1 
ATOM   6084  C CD  . GLN B 2 403 ? 157.184 166.051 162.505 1.00 32.82  ? 419 GLN B CD  1 
ATOM   6085  O OE1 . GLN B 2 403 ? 158.225 165.457 162.771 1.00 36.05  ? 419 GLN B OE1 1 
ATOM   6086  N NE2 . GLN B 2 403 ? 156.373 165.670 161.528 1.00 33.02  ? 419 GLN B NE2 1 
ATOM   6087  N N   . CYS B 2 404 ? 159.800 170.482 164.593 1.00 35.43  ? 420 CYS B N   1 
ATOM   6088  C CA  . CYS B 2 404 ? 160.829 171.515 164.590 1.00 33.24  ? 420 CYS B CA  1 
ATOM   6089  C C   . CYS B 2 404 ? 162.118 170.923 164.039 1.00 35.01  ? 420 CYS B C   1 
ATOM   6090  O O   . CYS B 2 404 ? 162.801 170.164 164.734 1.00 38.72  ? 420 CYS B O   1 
ATOM   6091  C CB  . CYS B 2 404 ? 161.034 172.059 166.001 1.00 35.38  ? 420 CYS B CB  1 
ATOM   6092  S SG  . CYS B 2 404 ? 162.150 173.458 166.132 1.00 55.64  ? 420 CYS B SG  1 
ATOM   6093  N N   . PHE B 2 405 ? 162.459 171.273 162.801 1.00 30.84  ? 421 PHE B N   1 
ATOM   6094  C CA  . PHE B 2 405 ? 163.700 170.826 162.179 1.00 30.07  ? 421 PHE B CA  1 
ATOM   6095  C C   . PHE B 2 405 ? 164.732 171.939 162.307 1.00 27.24  ? 421 PHE B C   1 
ATOM   6096  O O   . PHE B 2 405 ? 164.636 172.966 161.629 1.00 25.63  ? 421 PHE B O   1 
ATOM   6097  C CB  . PHE B 2 405 ? 163.487 170.443 160.717 1.00 28.80  ? 421 PHE B CB  1 
ATOM   6098  C CG  . PHE B 2 405 ? 164.648 169.704 160.116 1.00 28.84  ? 421 PHE B CG  1 
ATOM   6099  C CD1 . PHE B 2 405 ? 164.756 168.331 160.251 1.00 26.70  ? 421 PHE B CD1 1 
ATOM   6100  C CD2 . PHE B 2 405 ? 165.638 170.383 159.430 1.00 28.15  ? 421 PHE B CD2 1 
ATOM   6101  C CE1 . PHE B 2 405 ? 165.825 167.651 159.707 1.00 27.10  ? 421 PHE B CE1 1 
ATOM   6102  C CE2 . PHE B 2 405 ? 166.710 169.708 158.887 1.00 27.19  ? 421 PHE B CE2 1 
ATOM   6103  C CZ  . PHE B 2 405 ? 166.803 168.341 159.025 1.00 28.40  ? 421 PHE B CZ  1 
ATOM   6104  N N   . ASP B 2 406 ? 165.721 171.730 163.170 1.00 31.99  ? 422 ASP B N   1 
ATOM   6105  C CA  . ASP B 2 406 ? 166.761 172.725 163.400 1.00 33.55  ? 422 ASP B CA  1 
ATOM   6106  C C   . ASP B 2 406 ? 167.816 172.565 162.313 1.00 34.64  ? 422 ASP B C   1 
ATOM   6107  O O   . ASP B 2 406 ? 168.554 171.576 162.289 1.00 36.56  ? 422 ASP B O   1 
ATOM   6108  C CB  . ASP B 2 406 ? 167.352 172.561 164.797 1.00 36.80  ? 422 ASP B CB  1 
ATOM   6109  C CG  . ASP B 2 406 ? 168.620 173.364 164.997 1.00 41.62  ? 422 ASP B CG  1 
ATOM   6110  O OD1 . ASP B 2 406 ? 168.778 174.423 164.352 1.00 38.99  ? 422 ASP B OD1 1 
ATOM   6111  O OD2 . ASP B 2 406 ? 169.459 172.940 165.816 1.00 44.83  ? 422 ASP B OD2 1 
ATOM   6112  N N   . THR B 2 407 ? 167.878 173.541 161.407 1.00 33.91  ? 423 THR B N   1 
ATOM   6113  C CA  . THR B 2 407 ? 168.735 173.430 160.231 1.00 34.02  ? 423 THR B CA  1 
ATOM   6114  C C   . THR B 2 407 ? 170.213 173.392 160.603 1.00 38.29  ? 423 THR B C   1 
ATOM   6115  O O   . THR B 2 407 ? 170.982 172.614 160.025 1.00 38.05  ? 423 THR B O   1 
ATOM   6116  C CB  . THR B 2 407 ? 168.440 174.590 159.278 1.00 28.03  ? 423 THR B CB  1 
ATOM   6117  O OG1 . THR B 2 407 ? 167.252 174.309 158.529 1.00 24.55  ? 423 THR B OG1 1 
ATOM   6118  C CG2 . THR B 2 407 ? 169.589 174.823 158.338 1.00 29.80  ? 423 THR B CG2 1 
ATOM   6119  N N   . GLU B 2 408 ? 170.630 174.218 161.566 1.00 41.89  ? 424 GLU B N   1 
ATOM   6120  C CA  . GLU B 2 408 ? 172.055 174.364 161.853 1.00 43.79  ? 424 GLU B CA  1 
ATOM   6121  C C   . GLU B 2 408 ? 172.673 173.058 162.338 1.00 43.89  ? 424 GLU B C   1 
ATOM   6122  O O   . GLU B 2 408 ? 173.749 172.666 161.871 1.00 49.51  ? 424 GLU B O   1 
ATOM   6123  C CB  . GLU B 2 408 ? 172.268 175.473 162.882 1.00 47.87  ? 424 GLU B CB  1 
ATOM   6124  C CG  . GLU B 2 408 ? 173.707 175.620 163.347 1.00 54.50  ? 424 GLU B CG  1 
ATOM   6125  C CD  . GLU B 2 408 ? 174.386 176.843 162.765 1.00 63.32  ? 424 GLU B CD  1 
ATOM   6126  O OE1 . GLU B 2 408 ? 173.997 177.271 161.659 1.00 57.65  ? 424 GLU B OE1 1 
ATOM   6127  O OE2 . GLU B 2 408 ? 175.309 177.378 163.414 1.00 70.72  ? 424 GLU B OE2 1 
ATOM   6128  N N   . THR B 2 409 ? 172.018 172.372 163.269 1.00 41.89  ? 425 THR B N   1 
ATOM   6129  C CA  . THR B 2 409 ? 172.539 171.127 163.817 1.00 41.62  ? 425 THR B CA  1 
ATOM   6130  C C   . THR B 2 409 ? 171.873 169.885 163.240 1.00 43.07  ? 425 THR B C   1 
ATOM   6131  O O   . THR B 2 409 ? 172.215 168.773 163.655 1.00 47.94  ? 425 THR B O   1 
ATOM   6132  C CB  . THR B 2 409 ? 172.403 171.125 165.343 1.00 45.40  ? 425 THR B CB  1 
ATOM   6133  O OG1 . THR B 2 409 ? 171.121 170.603 165.712 1.00 40.90  ? 425 THR B OG1 1 
ATOM   6134  C CG2 . THR B 2 409 ? 172.566 172.531 165.898 1.00 47.66  ? 425 THR B CG2 1 
ATOM   6135  N N   . ASP B 2 410 ? 170.937 170.047 162.302 1.00 44.92  ? 426 ASP B N   1 
ATOM   6136  C CA  . ASP B 2 410 ? 170.293 168.929 161.609 1.00 41.35  ? 426 ASP B CA  1 
ATOM   6137  C C   . ASP B 2 410 ? 169.599 167.984 162.589 1.00 38.95  ? 426 ASP B C   1 
ATOM   6138  O O   . ASP B 2 410 ? 169.840 166.777 162.601 1.00 39.44  ? 426 ASP B O   1 
ATOM   6139  C CB  . ASP B 2 410 ? 171.297 168.171 160.738 1.00 41.03  ? 426 ASP B CB  1 
ATOM   6140  C CG  . ASP B 2 410 ? 172.042 169.080 159.782 1.00 47.27  ? 426 ASP B CG  1 
ATOM   6141  O OD1 . ASP B 2 410 ? 171.462 169.456 158.741 1.00 46.61  ? 426 ASP B OD1 1 
ATOM   6142  O OD2 . ASP B 2 410 ? 173.209 169.417 160.070 1.00 47.11  ? 426 ASP B OD2 1 
ATOM   6143  N N   . LYS B 2 411 ? 168.725 168.548 163.418 1.00 37.12  ? 427 LYS B N   1 
ATOM   6144  C CA  . LYS B 2 411 ? 167.955 167.784 164.388 1.00 39.86  ? 427 LYS B CA  1 
ATOM   6145  C C   . LYS B 2 411 ? 166.474 168.103 164.243 1.00 37.83  ? 427 LYS B C   1 
ATOM   6146  O O   . LYS B 2 411 ? 166.097 169.191 163.800 1.00 37.93  ? 427 LYS B O   1 
ATOM   6147  C CB  . LYS B 2 411 ? 168.411 168.077 165.823 1.00 40.59  ? 427 LYS B CB  1 
ATOM   6148  C CG  . LYS B 2 411 ? 169.859 167.727 166.103 1.00 40.38  ? 427 LYS B CG  1 
ATOM   6149  C CD  . LYS B 2 411 ? 169.978 166.378 166.791 1.00 41.62  ? 427 LYS B CD  1 
ATOM   6150  C CE  . LYS B 2 411 ? 171.225 165.630 166.343 1.00 43.86  ? 427 LYS B CE  1 
ATOM   6151  N NZ  . LYS B 2 411 ? 171.143 165.202 164.919 1.00 43.15  ? 427 LYS B NZ  1 
ATOM   6152  N N   . CYS B 2 412 ? 165.638 167.142 164.622 1.00 35.74  ? 428 CYS B N   1 
ATOM   6153  C CA  . CYS B 2 412 ? 164.192 167.283 164.541 1.00 39.13  ? 428 CYS B CA  1 
ATOM   6154  C C   . CYS B 2 412 ? 163.583 167.028 165.911 1.00 44.41  ? 428 CYS B C   1 
ATOM   6155  O O   . CYS B 2 412 ? 164.057 166.170 166.659 1.00 50.27  ? 428 CYS B O   1 
ATOM   6156  C CB  . CYS B 2 412 ? 163.595 166.318 163.507 1.00 41.49  ? 428 CYS B CB  1 
ATOM   6157  S SG  . CYS B 2 412 ? 161.884 166.670 163.048 1.00 48.03  ? 428 CYS B SG  1 
ATOM   6158  N N   . HIS B 2 413 ? 162.545 167.794 166.244 1.00 41.83  ? 429 HIS B N   1 
ATOM   6159  C CA  . HIS B 2 413 ? 161.836 167.643 167.506 1.00 41.50  ? 429 HIS B CA  1 
ATOM   6160  C C   . HIS B 2 413 ? 160.345 167.822 167.268 1.00 42.27  ? 429 HIS B C   1 
ATOM   6161  O O   . HIS B 2 413 ? 159.922 168.452 166.297 1.00 42.43  ? 429 HIS B O   1 
ATOM   6162  C CB  . HIS B 2 413 ? 162.319 168.648 168.563 1.00 42.29  ? 429 HIS B CB  1 
ATOM   6163  C CG  . HIS B 2 413 ? 163.802 168.851 168.579 1.00 50.04  ? 429 HIS B CG  1 
ATOM   6164  N ND1 . HIS B 2 413 ? 164.431 169.807 167.811 1.00 52.02  ? 429 HIS B ND1 1 
ATOM   6165  C CD2 . HIS B 2 413 ? 164.780 168.227 169.276 1.00 50.67  ? 429 HIS B CD2 1 
ATOM   6166  C CE1 . HIS B 2 413 ? 165.733 169.760 168.031 1.00 48.91  ? 429 HIS B CE1 1 
ATOM   6167  N NE2 . HIS B 2 413 ? 165.971 168.809 168.916 1.00 50.81  ? 429 HIS B NE2 1 
ATOM   6168  N N   . VAL B 2 414 ? 159.547 167.259 168.171 1.00 45.37  ? 430 VAL B N   1 
ATOM   6169  C CA  . VAL B 2 414 ? 158.095 167.391 168.147 1.00 39.07  ? 430 VAL B CA  1 
ATOM   6170  C C   . VAL B 2 414 ? 157.668 168.186 169.373 1.00 40.56  ? 430 VAL B C   1 
ATOM   6171  O O   . VAL B 2 414 ? 158.033 167.839 170.503 1.00 44.19  ? 430 VAL B O   1 
ATOM   6172  C CB  . VAL B 2 414 ? 157.400 166.020 168.113 1.00 37.85  ? 430 VAL B CB  1 
ATOM   6173  C CG1 . VAL B 2 414 ? 155.947 166.175 167.706 1.00 36.27  ? 430 VAL B CG1 1 
ATOM   6174  C CG2 . VAL B 2 414 ? 158.122 165.083 167.165 1.00 41.64  ? 430 VAL B CG2 1 
ATOM   6175  N N   . LYS B 2 415 ? 156.904 169.246 169.150 1.00 38.54  ? 431 LYS B N   1 
ATOM   6176  C CA  . LYS B 2 415 ? 156.459 170.092 170.251 1.00 33.98  ? 431 LYS B CA  1 
ATOM   6177  C C   . LYS B 2 415 ? 155.398 169.369 171.072 1.00 36.91  ? 431 LYS B C   1 
ATOM   6178  O O   . LYS B 2 415 ? 154.476 168.777 170.498 1.00 38.71  ? 431 LYS B O   1 
ATOM   6179  C CB  . LYS B 2 415 ? 155.912 171.412 169.719 1.00 32.84  ? 431 LYS B CB  1 
ATOM   6180  C CG  . LYS B 2 415 ? 156.920 172.210 168.916 1.00 35.04  ? 431 LYS B CG  1 
ATOM   6181  C CD  . LYS B 2 415 ? 158.212 172.371 169.692 1.00 38.60  ? 431 LYS B CD  1 
ATOM   6182  C CE  . LYS B 2 415 ? 159.247 173.135 168.895 1.00 40.72  ? 431 LYS B CE  1 
ATOM   6183  N NZ  . LYS B 2 415 ? 160.580 173.109 169.556 1.00 48.57  ? 431 LYS B NZ  1 
ATOM   6184  N N   . PRO B 2 416 ? 155.496 169.381 172.404 1.00 36.69  ? 432 PRO B N   1 
ATOM   6185  C CA  . PRO B 2 416 ? 154.475 168.703 173.221 1.00 35.23  ? 432 PRO B CA  1 
ATOM   6186  C C   . PRO B 2 416 ? 153.073 169.253 173.031 1.00 36.03  ? 432 PRO B C   1 
ATOM   6187  O O   . PRO B 2 416 ? 152.102 168.492 173.124 1.00 36.24  ? 432 PRO B O   1 
ATOM   6188  C CB  . PRO B 2 416 ? 154.975 168.916 174.657 1.00 32.93  ? 432 PRO B CB  1 
ATOM   6189  C CG  . PRO B 2 416 ? 155.950 170.041 174.574 1.00 32.67  ? 432 PRO B CG  1 
ATOM   6190  C CD  . PRO B 2 416 ? 156.574 169.953 173.225 1.00 33.32  ? 432 PRO B CD  1 
ATOM   6191  N N   . TYR B 2 417 ? 152.934 170.549 172.770 1.00 34.73  ? 433 TYR B N   1 
ATOM   6192  C CA  . TYR B 2 417 ? 151.628 171.146 172.555 1.00 32.60  ? 433 TYR B CA  1 
ATOM   6193  C C   . TYR B 2 417 ? 151.172 170.929 171.114 1.00 34.20  ? 433 TYR B C   1 
ATOM   6194  O O   . TYR B 2 417 ? 151.920 170.448 170.259 1.00 38.41  ? 433 TYR B O   1 
ATOM   6195  C CB  . TYR B 2 417 ? 151.656 172.636 172.895 1.00 34.17  ? 433 TYR B CB  1 
ATOM   6196  C CG  . TYR B 2 417 ? 152.884 173.369 172.405 1.00 32.93  ? 433 TYR B CG  1 
ATOM   6197  C CD1 . TYR B 2 417 ? 154.057 173.376 173.147 1.00 32.64  ? 433 TYR B CD1 1 
ATOM   6198  C CD2 . TYR B 2 417 ? 152.868 174.061 171.204 1.00 31.32  ? 433 TYR B CD2 1 
ATOM   6199  C CE1 . TYR B 2 417 ? 155.176 174.042 172.702 1.00 32.17  ? 433 TYR B CE1 1 
ATOM   6200  C CE2 . TYR B 2 417 ? 153.982 174.731 170.754 1.00 30.88  ? 433 TYR B CE2 1 
ATOM   6201  C CZ  . TYR B 2 417 ? 155.133 174.720 171.506 1.00 33.45  ? 433 TYR B CZ  1 
ATOM   6202  O OH  . TYR B 2 417 ? 156.248 175.389 171.059 1.00 38.14  ? 433 TYR B OH  1 
ATOM   6203  N N   . VAL B 2 418 ? 149.918 171.295 170.846 1.00 32.31  ? 434 VAL B N   1 
ATOM   6204  C CA  . VAL B 2 418 ? 149.300 171.076 169.546 1.00 33.99  ? 434 VAL B CA  1 
ATOM   6205  C C   . VAL B 2 418 ? 148.676 172.377 169.058 1.00 36.20  ? 434 VAL B C   1 
ATOM   6206  O O   . VAL B 2 418 ? 148.424 173.304 169.829 1.00 37.38  ? 434 VAL B O   1 
ATOM   6207  C CB  . VAL B 2 418 ? 148.239 169.955 169.588 1.00 33.25  ? 434 VAL B CB  1 
ATOM   6208  C CG1 . VAL B 2 418 ? 148.905 168.597 169.706 1.00 32.50  ? 434 VAL B CG1 1 
ATOM   6209  C CG2 . VAL B 2 418 ? 147.273 170.181 170.734 1.00 33.02  ? 434 VAL B CG2 1 
ATOM   6210  N N   . LEU B 2 419 ? 148.435 172.433 167.751 1.00 34.58  ? 435 LEU B N   1 
ATOM   6211  C CA  . LEU B 2 419 ? 147.811 173.600 167.152 1.00 34.56  ? 435 LEU B CA  1 
ATOM   6212  C C   . LEU B 2 419 ? 146.337 173.681 167.547 1.00 39.48  ? 435 LEU B C   1 
ATOM   6213  O O   . LEU B 2 419 ? 145.716 172.665 167.870 1.00 38.91  ? 435 LEU B O   1 
ATOM   6214  C CB  . LEU B 2 419 ? 147.935 173.549 165.631 1.00 37.46  ? 435 LEU B CB  1 
ATOM   6215  C CG  . LEU B 2 419 ? 149.310 173.813 165.020 1.00 38.57  ? 435 LEU B CG  1 
ATOM   6216  C CD1 . LEU B 2 419 ? 149.522 172.938 163.800 1.00 33.06  ? 435 LEU B CD1 1 
ATOM   6217  C CD2 . LEU B 2 419 ? 149.462 175.279 164.660 1.00 37.38  ? 435 LEU B CD2 1 
ATOM   6218  N N   . PRO B 2 420 ? 145.754 174.885 167.541 1.00 40.39  ? 436 PRO B N   1 
ATOM   6219  C CA  . PRO B 2 420 ? 144.315 174.996 167.828 1.00 39.98  ? 436 PRO B CA  1 
ATOM   6220  C C   . PRO B 2 420 ? 143.442 174.237 166.846 1.00 44.32  ? 436 PRO B C   1 
ATOM   6221  O O   . PRO B 2 420 ? 142.397 173.706 167.242 1.00 46.81  ? 436 PRO B O   1 
ATOM   6222  C CB  . PRO B 2 420 ? 144.058 176.508 167.755 1.00 38.70  ? 436 PRO B CB  1 
ATOM   6223  C CG  . PRO B 2 420 ? 145.390 177.139 167.916 1.00 38.50  ? 436 PRO B CG  1 
ATOM   6224  C CD  . PRO B 2 420 ? 146.370 176.199 167.303 1.00 36.73  ? 436 PRO B CD  1 
ATOM   6225  N N   . PHE B 2 421 ? 143.833 174.173 165.578 1.00 43.43  ? 437 PHE B N   1 
ATOM   6226  C CA  . PHE B 2 421 ? 143.080 173.475 164.548 1.00 40.78  ? 437 PHE B CA  1 
ATOM   6227  C C   . PHE B 2 421 ? 143.940 172.382 163.924 1.00 42.15  ? 437 PHE B C   1 
ATOM   6228  O O   . PHE B 2 421 ? 145.150 172.306 164.145 1.00 40.24  ? 437 PHE B O   1 
ATOM   6229  C CB  . PHE B 2 421 ? 142.572 174.444 163.469 1.00 40.70  ? 437 PHE B CB  1 
ATOM   6230  C CG  . PHE B 2 421 ? 143.509 175.586 163.171 1.00 43.25  ? 437 PHE B CG  1 
ATOM   6231  C CD1 . PHE B 2 421 ? 144.850 175.361 162.915 1.00 41.01  ? 437 PHE B CD1 1 
ATOM   6232  C CD2 . PHE B 2 421 ? 143.035 176.886 163.119 1.00 45.15  ? 437 PHE B CD2 1 
ATOM   6233  C CE1 . PHE B 2 421 ? 145.703 176.409 162.637 1.00 36.67  ? 437 PHE B CE1 1 
ATOM   6234  C CE2 . PHE B 2 421 ? 143.884 177.937 162.836 1.00 42.10  ? 437 PHE B CE2 1 
ATOM   6235  C CZ  . PHE B 2 421 ? 145.219 177.696 162.595 1.00 37.46  ? 437 PHE B CZ  1 
ATOM   6236  N N   . ALA B 2 422 ? 143.292 171.530 163.132 1.00 42.58  ? 438 ALA B N   1 
ATOM   6237  C CA  . ALA B 2 422 ? 143.937 170.382 162.514 1.00 37.63  ? 438 ALA B CA  1 
ATOM   6238  C C   . ALA B 2 422 ? 143.581 170.316 161.037 1.00 38.40  ? 438 ALA B C   1 
ATOM   6239  O O   . ALA B 2 422 ? 142.546 170.831 160.606 1.00 41.67  ? 438 ALA B O   1 
ATOM   6240  C CB  . ALA B 2 422 ? 143.530 169.074 163.201 1.00 35.91  ? 438 ALA B CB  1 
ATOM   6241  N N   . GLY B 2 423 ? 144.455 169.678 160.263 1.00 36.67  ? 439 GLY B N   1 
ATOM   6242  C CA  . GLY B 2 423 ? 144.206 169.478 158.850 1.00 36.19  ? 439 GLY B CA  1 
ATOM   6243  C C   . GLY B 2 423 ? 145.159 170.234 157.951 1.00 36.09  ? 439 GLY B C   1 
ATOM   6244  O O   . GLY B 2 423 ? 146.354 170.329 158.240 1.00 38.24  ? 439 GLY B O   1 
ATOM   6245  N N   . ARG B 2 424 ? 144.640 170.772 156.852 1.00 39.12  ? 440 ARG B N   1 
ATOM   6246  C CA  . ARG B 2 424 ? 145.444 171.547 155.921 1.00 42.15  ? 440 ARG B CA  1 
ATOM   6247  C C   . ARG B 2 424 ? 145.390 173.022 156.296 1.00 41.35  ? 440 ARG B C   1 
ATOM   6248  O O   . ARG B 2 424 ? 144.355 173.525 156.744 1.00 44.40  ? 440 ARG B O   1 
ATOM   6249  C CB  . ARG B 2 424 ? 144.962 171.331 154.484 1.00 50.61  ? 440 ARG B CB  1 
ATOM   6250  C CG  . ARG B 2 424 ? 144.128 172.453 153.898 1.00 54.81  ? 440 ARG B CG  1 
ATOM   6251  C CD  . ARG B 2 424 ? 143.805 172.182 152.441 1.00 60.30  ? 440 ARG B CD  1 
ATOM   6252  N NE  . ARG B 2 424 ? 143.542 170.769 152.189 1.00 67.87  ? 440 ARG B NE  1 
ATOM   6253  C CZ  . ARG B 2 424 ? 142.375 170.175 152.395 1.00 65.33  ? 440 ARG B CZ  1 
ATOM   6254  N NH1 . ARG B 2 424 ? 141.332 170.841 152.863 1.00 67.38  ? 440 ARG B NH1 1 
ATOM   6255  N NH2 . ARG B 2 424 ? 142.250 168.879 152.125 1.00 58.28  ? 440 ARG B NH2 1 
ATOM   6256  N N   . MET B 2 425 ? 146.521 173.705 156.139 1.00 38.61  ? 441 MET B N   1 
ATOM   6257  C CA  . MET B 2 425 ? 146.625 175.097 156.551 1.00 35.89  ? 441 MET B CA  1 
ATOM   6258  C C   . MET B 2 425 ? 147.702 175.784 155.728 1.00 33.34  ? 441 MET B C   1 
ATOM   6259  O O   . MET B 2 425 ? 148.519 175.136 155.071 1.00 35.13  ? 441 MET B O   1 
ATOM   6260  C CB  . MET B 2 425 ? 146.943 175.220 158.045 1.00 37.13  ? 441 MET B CB  1 
ATOM   6261  C CG  . MET B 2 425 ? 147.863 174.137 158.576 1.00 34.70  ? 441 MET B CG  1 
ATOM   6262  S SD  . MET B 2 425 ? 147.805 173.985 160.368 1.00 38.00  ? 441 MET B SD  1 
ATOM   6263  C CE  . MET B 2 425 ? 146.230 173.168 160.571 1.00 35.78  ? 441 MET B CE  1 
ATOM   6264  N N   . HIS B 2 426 ? 147.688 177.112 155.778 1.00 33.94  ? 442 HIS B N   1 
ATOM   6265  C CA  . HIS B 2 426 ? 148.683 177.949 155.127 1.00 29.11  ? 442 HIS B CA  1 
ATOM   6266  C C   . HIS B 2 426 ? 149.358 178.822 156.173 1.00 28.46  ? 442 HIS B C   1 
ATOM   6267  O O   . HIS B 2 426 ? 148.692 179.391 157.042 1.00 31.95  ? 442 HIS B O   1 
ATOM   6268  C CB  . HIS B 2 426 ? 148.046 178.823 154.043 1.00 30.91  ? 442 HIS B CB  1 
ATOM   6269  C CG  . HIS B 2 426 ? 148.961 179.132 152.901 1.00 30.19  ? 442 HIS B CG  1 
ATOM   6270  N ND1 . HIS B 2 426 ? 149.105 180.401 152.385 1.00 29.77  ? 442 HIS B ND1 1 
ATOM   6271  C CD2 . HIS B 2 426 ? 149.780 178.336 152.175 1.00 27.63  ? 442 HIS B CD2 1 
ATOM   6272  C CE1 . HIS B 2 426 ? 149.972 180.374 151.390 1.00 27.80  ? 442 HIS B CE1 1 
ATOM   6273  N NE2 . HIS B 2 426 ? 150.397 179.133 151.242 1.00 29.16  ? 442 HIS B NE2 1 
ATOM   6274  N N   . ALA B 2 427 ? 150.680 178.929 156.087 1.00 28.37  ? 443 ALA B N   1 
ATOM   6275  C CA  . ALA B 2 427 ? 151.468 179.658 157.067 1.00 23.91  ? 443 ALA B CA  1 
ATOM   6276  C C   . ALA B 2 427 ? 152.250 180.781 156.399 1.00 26.36  ? 443 ALA B C   1 
ATOM   6277  O O   . ALA B 2 427 ? 152.678 180.665 155.248 1.00 27.15  ? 443 ALA B O   1 
ATOM   6278  C CB  . ALA B 2 427 ? 152.431 178.727 157.808 1.00 21.77  ? 443 ALA B CB  1 
ATOM   6279  N N   . ALA B 2 428 ? 152.424 181.873 157.139 1.00 26.59  ? 444 ALA B N   1 
ATOM   6280  C CA  . ALA B 2 428 ? 153.232 183.006 156.716 1.00 21.52  ? 444 ALA B CA  1 
ATOM   6281  C C   . ALA B 2 428 ? 153.994 183.535 157.920 1.00 21.22  ? 444 ALA B C   1 
ATOM   6282  O O   . ALA B 2 428 ? 153.454 183.586 159.027 1.00 25.16  ? 444 ALA B O   1 
ATOM   6283  C CB  . ALA B 2 428 ? 152.375 184.121 156.108 1.00 21.27  ? 444 ALA B CB  1 
ATOM   6284  N N   . VAL B 2 429 ? 155.243 183.926 157.704 1.00 20.56  ? 445 VAL B N   1 
ATOM   6285  C CA  . VAL B 2 429 ? 156.104 184.424 158.769 1.00 21.27  ? 445 VAL B CA  1 
ATOM   6286  C C   . VAL B 2 429 ? 156.072 185.945 158.730 1.00 22.16  ? 445 VAL B C   1 
ATOM   6287  O O   . VAL B 2 429 ? 156.586 186.564 157.792 1.00 25.98  ? 445 VAL B O   1 
ATOM   6288  C CB  . VAL B 2 429 ? 157.537 183.895 158.633 1.00 20.81  ? 445 VAL B CB  1 
ATOM   6289  C CG1 . VAL B 2 429 ? 158.440 184.546 159.663 1.00 20.92  ? 445 VAL B CG1 1 
ATOM   6290  C CG2 . VAL B 2 429 ? 157.560 182.388 158.784 1.00 18.91  ? 445 VAL B CG2 1 
ATOM   6291  N N   . HIS B 2 430 ? 155.467 186.551 159.746 1.00 19.74  ? 446 HIS B N   1 
ATOM   6292  C CA  . HIS B 2 430 ? 155.459 187.997 159.923 1.00 20.22  ? 446 HIS B CA  1 
ATOM   6293  C C   . HIS B 2 430 ? 156.281 188.332 161.158 1.00 24.11  ? 446 HIS B C   1 
ATOM   6294  O O   . HIS B 2 430 ? 155.945 187.896 162.264 1.00 28.46  ? 446 HIS B O   1 
ATOM   6295  C CB  . HIS B 2 430 ? 154.032 188.524 160.067 1.00 23.96  ? 446 HIS B CB  1 
ATOM   6296  C CG  . HIS B 2 430 ? 153.918 190.011 159.937 1.00 27.10  ? 446 HIS B CG  1 
ATOM   6297  N ND1 . HIS B 2 430 ? 154.609 190.731 158.988 1.00 28.86  ? 446 HIS B ND1 1 
ATOM   6298  C CD2 . HIS B 2 430 ? 153.191 190.913 160.636 1.00 24.27  ? 446 HIS B CD2 1 
ATOM   6299  C CE1 . HIS B 2 430 ? 154.314 192.012 159.108 1.00 28.46  ? 446 HIS B CE1 1 
ATOM   6300  N NE2 . HIS B 2 430 ? 153.456 192.150 160.102 1.00 26.47  ? 446 HIS B NE2 1 
ATOM   6301  N N   . LYS B 2 431 ? 157.348 189.105 160.969 1.00 22.46  ? 447 LYS B N   1 
ATOM   6302  C CA  . LYS B 2 431 ? 158.275 189.485 162.044 1.00 21.74  ? 447 LYS B CA  1 
ATOM   6303  C C   . LYS B 2 431 ? 158.844 188.193 162.627 1.00 22.07  ? 447 LYS B C   1 
ATOM   6304  O O   . LYS B 2 431 ? 159.379 187.370 161.868 1.00 26.29  ? 447 LYS B O   1 
ATOM   6305  C CB  . LYS B 2 431 ? 157.568 190.401 163.037 1.00 20.75  ? 447 LYS B CB  1 
ATOM   6306  C CG  . LYS B 2 431 ? 156.873 191.592 162.410 1.00 20.97  ? 447 LYS B CG  1 
ATOM   6307  C CD  . LYS B 2 431 ? 157.858 192.685 162.057 1.00 20.75  ? 447 LYS B CD  1 
ATOM   6308  C CE  . LYS B 2 431 ? 157.141 193.931 161.575 1.00 22.52  ? 447 LYS B CE  1 
ATOM   6309  N NZ  . LYS B 2 431 ? 157.482 194.250 160.163 1.00 30.89  ? 447 LYS B NZ  1 
ATOM   6310  N N   . ASP B 2 432 ? 158.761 187.971 163.938 1.00 19.07  ? 448 ASP B N   1 
ATOM   6311  C CA  . ASP B 2 432 ? 159.245 186.754 164.573 1.00 18.09  ? 448 ASP B CA  1 
ATOM   6312  C C   . ASP B 2 432 ? 158.123 185.764 164.850 1.00 22.28  ? 448 ASP B C   1 
ATOM   6313  O O   . ASP B 2 432 ? 158.274 184.887 165.706 1.00 22.01  ? 448 ASP B O   1 
ATOM   6314  C CB  . ASP B 2 432 ? 159.976 187.093 165.871 1.00 23.13  ? 448 ASP B CB  1 
ATOM   6315  C CG  . ASP B 2 432 ? 159.244 188.137 166.696 1.00 26.64  ? 448 ASP B CG  1 
ATOM   6316  O OD1 . ASP B 2 432 ? 158.630 189.043 166.097 1.00 26.02  ? 448 ASP B OD1 1 
ATOM   6317  O OD2 . ASP B 2 432 ? 159.282 188.053 167.941 1.00 23.11  ? 448 ASP B OD2 1 
ATOM   6318  N N   . LEU B 2 433 ? 157.002 185.890 164.147 1.00 21.32  ? 449 LEU B N   1 
ATOM   6319  C CA  . LEU B 2 433 ? 155.811 185.108 164.423 1.00 19.11  ? 449 LEU B CA  1 
ATOM   6320  C C   . LEU B 2 433 ? 155.350 184.417 163.149 1.00 18.67  ? 449 LEU B C   1 
ATOM   6321  O O   . LEU B 2 433 ? 155.646 184.857 162.037 1.00 20.54  ? 449 LEU B O   1 
ATOM   6322  C CB  . LEU B 2 433 ? 154.682 185.989 164.980 1.00 21.56  ? 449 LEU B CB  1 
ATOM   6323  C CG  . LEU B 2 433 ? 155.071 187.034 166.029 1.00 21.17  ? 449 LEU B CG  1 
ATOM   6324  C CD1 . LEU B 2 433 ? 154.105 188.198 166.004 1.00 21.65  ? 449 LEU B CD1 1 
ATOM   6325  C CD2 . LEU B 2 433 ? 155.127 186.422 167.412 1.00 17.43  ? 449 LEU B CD2 1 
ATOM   6326  N N   . VAL B 2 434 ? 154.622 183.320 163.328 1.00 20.86  ? 450 VAL B N   1 
ATOM   6327  C CA  . VAL B 2 434 ? 154.027 182.570 162.230 1.00 19.04  ? 450 VAL B CA  1 
ATOM   6328  C C   . VAL B 2 434 ? 152.521 182.773 162.279 1.00 21.26  ? 450 VAL B C   1 
ATOM   6329  O O   . VAL B 2 434 ? 151.886 182.510 163.307 1.00 23.37  ? 450 VAL B O   1 
ATOM   6330  C CB  . VAL B 2 434 ? 154.378 181.074 162.306 1.00 18.58  ? 450 VAL B CB  1 
ATOM   6331  C CG1 . VAL B 2 434 ? 153.897 180.355 161.061 1.00 19.69  ? 450 VAL B CG1 1 
ATOM   6332  C CG2 . VAL B 2 434 ? 155.866 180.887 162.481 1.00 20.05  ? 450 VAL B CG2 1 
ATOM   6333  N N   . PHE B 2 435 ? 151.955 183.242 161.176 1.00 19.67  ? 451 PHE B N   1 
ATOM   6334  C CA  . PHE B 2 435 ? 150.513 183.358 161.023 1.00 22.83  ? 451 PHE B CA  1 
ATOM   6335  C C   . PHE B 2 435 ? 150.009 182.131 160.278 1.00 25.79  ? 451 PHE B C   1 
ATOM   6336  O O   . PHE B 2 435 ? 150.554 181.772 159.232 1.00 27.72  ? 451 PHE B O   1 
ATOM   6337  C CB  . PHE B 2 435 ? 150.143 184.635 160.269 1.00 23.13  ? 451 PHE B CB  1 
ATOM   6338  C CG  . PHE B 2 435 ? 150.161 185.867 161.122 1.00 25.40  ? 451 PHE B CG  1 
ATOM   6339  C CD1 . PHE B 2 435 ? 151.352 186.503 161.416 1.00 24.53  ? 451 PHE B CD1 1 
ATOM   6340  C CD2 . PHE B 2 435 ? 148.986 186.393 161.627 1.00 29.20  ? 451 PHE B CD2 1 
ATOM   6341  C CE1 . PHE B 2 435 ? 151.372 187.637 162.202 1.00 24.90  ? 451 PHE B CE1 1 
ATOM   6342  C CE2 . PHE B 2 435 ? 149.001 187.527 162.413 1.00 30.92  ? 451 PHE B CE2 1 
ATOM   6343  C CZ  . PHE B 2 435 ? 150.195 188.150 162.699 1.00 26.52  ? 451 PHE B CZ  1 
ATOM   6344  N N   . ILE B 2 436 ? 148.988 181.479 160.827 1.00 26.95  ? 452 ILE B N   1 
ATOM   6345  C CA  . ILE B 2 436 ? 148.445 180.246 160.270 1.00 26.48  ? 452 ILE B CA  1 
ATOM   6346  C C   . ILE B 2 436 ? 146.960 180.444 160.016 1.00 31.28  ? 452 ILE B C   1 
ATOM   6347  O O   . ILE B 2 436 ? 146.248 180.988 160.867 1.00 34.87  ? 452 ILE B O   1 
ATOM   6348  C CB  . ILE B 2 436 ? 148.682 179.042 161.200 1.00 27.41  ? 452 ILE B CB  1 
ATOM   6349  C CG1 . ILE B 2 436 ? 150.152 178.951 161.606 1.00 23.45  ? 452 ILE B CG1 1 
ATOM   6350  C CG2 . ILE B 2 436 ? 148.257 177.757 160.520 1.00 30.61  ? 452 ILE B CG2 1 
ATOM   6351  C CD1 . ILE B 2 436 ? 150.362 178.769 163.087 1.00 21.96  ? 452 ILE B CD1 1 
ATOM   6352  N N   . VAL B 2 437 ? 146.498 180.010 158.848 1.00 36.38  ? 453 VAL B N   1 
ATOM   6353  C CA  . VAL B 2 437 ? 145.090 180.071 158.481 1.00 39.49  ? 453 VAL B CA  1 
ATOM   6354  C C   . VAL B 2 437 ? 144.666 178.700 157.971 1.00 42.23  ? 453 VAL B C   1 
ATOM   6355  O O   . VAL B 2 437 ? 145.412 178.038 157.242 1.00 41.70  ? 453 VAL B O   1 
ATOM   6356  C CB  . VAL B 2 437 ? 144.817 181.171 157.429 1.00 37.13  ? 453 VAL B CB  1 
ATOM   6357  C CG1 . VAL B 2 437 ? 145.560 180.889 156.135 1.00 36.86  ? 453 VAL B CG1 1 
ATOM   6358  C CG2 . VAL B 2 437 ? 143.328 181.310 157.177 1.00 42.42  ? 453 VAL B CG2 1 
ATOM   6359  N N   . ALA B 2 438 ? 143.482 178.258 158.387 1.00 47.16  ? 454 ALA B N   1 
ATOM   6360  C CA  . ALA B 2 438 ? 142.941 176.972 157.978 1.00 50.46  ? 454 ALA B CA  1 
ATOM   6361  C C   . ALA B 2 438 ? 141.475 177.156 157.611 1.00 60.68  ? 454 ALA B C   1 
ATOM   6362  O O   . ALA B 2 438 ? 140.957 178.276 157.576 1.00 67.76  ? 454 ALA B O   1 
ATOM   6363  C CB  . ALA B 2 438 ? 143.113 175.919 159.078 1.00 46.52  ? 454 ALA B CB  1 
ATOM   6364  N N   . GLU B 2 439 ? 140.803 176.044 157.329 1.00 63.27  ? 455 GLU B N   1 
ATOM   6365  C CA  . GLU B 2 439 ? 139.384 176.096 157.005 1.00 69.55  ? 455 GLU B CA  1 
ATOM   6366  C C   . GLU B 2 439 ? 138.568 176.331 158.269 1.00 74.32  ? 455 GLU B C   1 
ATOM   6367  O O   . GLU B 2 439 ? 138.711 175.605 159.257 1.00 71.94  ? 455 GLU B O   1 
ATOM   6368  C CB  . GLU B 2 439 ? 138.946 174.800 156.325 1.00 71.41  ? 455 GLU B CB  1 
ATOM   6369  C CG  . GLU B 2 439 ? 139.990 174.197 155.399 1.00 72.98  ? 455 GLU B CG  1 
ATOM   6370  C CD  . GLU B 2 439 ? 140.527 172.873 155.906 1.00 72.49  ? 455 GLU B CD  1 
ATOM   6371  O OE1 . GLU B 2 439 ? 141.117 172.849 157.007 1.00 66.94  ? 455 GLU B OE1 1 
ATOM   6372  O OE2 . GLU B 2 439 ? 140.358 171.854 155.204 1.00 71.20  ? 455 GLU B OE2 1 
ATOM   6373  N N   . GLY B 2 440 ? 137.707 177.344 158.236 1.00 77.07  ? 456 GLY B N   1 
ATOM   6374  C CA  . GLY B 2 440 ? 136.856 177.632 159.374 1.00 80.23  ? 456 GLY B CA  1 
ATOM   6375  C C   . GLY B 2 440 ? 136.919 179.065 159.859 1.00 83.12  ? 456 GLY B C   1 
ATOM   6376  O O   . GLY B 2 440 ? 136.494 179.359 160.981 1.00 82.36  ? 456 GLY B O   1 
ATOM   6377  N N   . ASP B 2 441 ? 137.446 179.963 159.024 1.00 81.36  ? 457 ASP B N   1 
ATOM   6378  C CA  . ASP B 2 441 ? 137.485 181.398 159.311 1.00 81.00  ? 457 ASP B CA  1 
ATOM   6379  C C   . ASP B 2 441 ? 138.222 181.683 160.622 1.00 80.32  ? 457 ASP B C   1 
ATOM   6380  O O   . ASP B 2 441 ? 137.714 182.354 161.523 1.00 77.32  ? 457 ASP B O   1 
ATOM   6381  C CB  . ASP B 2 441 ? 136.069 181.981 159.337 1.00 87.24  ? 457 ASP B CB  1 
ATOM   6382  C CG  . ASP B 2 441 ? 135.415 181.980 157.972 1.00 95.97  ? 457 ASP B CG  1 
ATOM   6383  O OD1 . ASP B 2 441 ? 135.949 181.319 157.058 1.00 92.53  ? 457 ASP B OD1 1 
ATOM   6384  O OD2 . ASP B 2 441 ? 134.369 182.644 157.814 1.00 104.06 ? 457 ASP B OD2 1 
ATOM   6385  N N   . SER B 2 442 ? 139.441 181.156 160.713 1.00 80.19  ? 458 SER B N   1 
ATOM   6386  C CA  . SER B 2 442 ? 140.276 181.312 161.896 1.00 71.74  ? 458 SER B CA  1 
ATOM   6387  C C   . SER B 2 442 ? 141.675 181.730 161.473 1.00 60.44  ? 458 SER B C   1 
ATOM   6388  O O   . SER B 2 442 ? 142.232 181.170 160.525 1.00 56.97  ? 458 SER B O   1 
ATOM   6389  C CB  . SER B 2 442 ? 140.336 180.010 162.706 1.00 72.73  ? 458 SER B CB  1 
ATOM   6390  O OG  . SER B 2 442 ? 139.037 179.539 163.022 1.00 76.91  ? 458 SER B OG  1 
ATOM   6391  N N   . LEU B 2 443 ? 142.236 182.710 162.177 1.00 51.60  ? 459 LEU B N   1 
ATOM   6392  C CA  . LEU B 2 443 ? 143.603 183.166 161.956 1.00 44.90  ? 459 LEU B CA  1 
ATOM   6393  C C   . LEU B 2 443 ? 144.354 183.070 163.275 1.00 41.78  ? 459 LEU B C   1 
ATOM   6394  O O   . LEU B 2 443 ? 143.951 183.685 164.267 1.00 46.13  ? 459 LEU B O   1 
ATOM   6395  C CB  . LEU B 2 443 ? 143.627 184.599 161.419 1.00 48.18  ? 459 LEU B CB  1 
ATOM   6396  C CG  . LEU B 2 443 ? 144.965 185.169 160.943 1.00 39.85  ? 459 LEU B CG  1 
ATOM   6397  C CD1 . LEU B 2 443 ? 145.688 184.192 160.039 1.00 36.60  ? 459 LEU B CD1 1 
ATOM   6398  C CD2 . LEU B 2 443 ? 144.742 186.483 160.226 1.00 41.25  ? 459 LEU B CD2 1 
ATOM   6399  N N   . VAL B 2 444 ? 145.442 182.305 163.285 1.00 38.45  ? 460 VAL B N   1 
ATOM   6400  C CA  . VAL B 2 444 ? 146.198 182.015 164.496 1.00 34.59  ? 460 VAL B CA  1 
ATOM   6401  C C   . VAL B 2 444 ? 147.599 182.588 164.342 1.00 33.14  ? 460 VAL B C   1 
ATOM   6402  O O   . VAL B 2 444 ? 148.270 182.337 163.335 1.00 31.05  ? 460 VAL B O   1 
ATOM   6403  C CB  . VAL B 2 444 ? 146.249 180.502 164.778 1.00 30.89  ? 460 VAL B CB  1 
ATOM   6404  C CG1 . VAL B 2 444 ? 147.493 180.137 165.568 1.00 28.29  ? 460 VAL B CG1 1 
ATOM   6405  C CG2 . VAL B 2 444 ? 145.003 180.062 165.516 1.00 37.78  ? 460 VAL B CG2 1 
ATOM   6406  N N   . CYS B 2 445 ? 148.031 183.365 165.332 1.00 31.43  ? 461 CYS B N   1 
ATOM   6407  C CA  . CYS B 2 445 ? 149.398 183.858 165.410 1.00 25.71  ? 461 CYS B CA  1 
ATOM   6408  C C   . CYS B 2 445 ? 150.157 183.010 166.420 1.00 26.73  ? 461 CYS B C   1 
ATOM   6409  O O   . CYS B 2 445 ? 149.773 182.942 167.592 1.00 28.50  ? 461 CYS B O   1 
ATOM   6410  C CB  . CYS B 2 445 ? 149.432 185.332 165.810 1.00 29.62  ? 461 CYS B CB  1 
ATOM   6411  S SG  . CYS B 2 445 ? 151.027 186.135 165.549 1.00 33.92  ? 461 CYS B SG  1 
ATOM   6412  N N   . TYR B 2 446 ? 151.230 182.370 165.968 1.00 25.11  ? 462 TYR B N   1 
ATOM   6413  C CA  . TYR B 2 446 ? 151.994 181.432 166.778 1.00 22.01  ? 462 TYR B CA  1 
ATOM   6414  C C   . TYR B 2 446 ? 153.335 182.053 167.143 1.00 22.26  ? 462 TYR B C   1 
ATOM   6415  O O   . TYR B 2 446 ? 154.058 182.539 166.269 1.00 20.15  ? 462 TYR B O   1 
ATOM   6416  C CB  . TYR B 2 446 ? 152.189 180.114 166.023 1.00 20.26  ? 462 TYR B CB  1 
ATOM   6417  C CG  . TYR B 2 446 ? 153.103 179.112 166.691 1.00 23.53  ? 462 TYR B CG  1 
ATOM   6418  C CD1 . TYR B 2 446 ? 153.042 178.886 168.059 1.00 24.27  ? 462 TYR B CD1 1 
ATOM   6419  C CD2 . TYR B 2 446 ? 154.016 178.376 165.947 1.00 19.74  ? 462 TYR B CD2 1 
ATOM   6420  C CE1 . TYR B 2 446 ? 153.872 177.967 168.667 1.00 24.49  ? 462 TYR B CE1 1 
ATOM   6421  C CE2 . TYR B 2 446 ? 154.848 177.456 166.547 1.00 19.84  ? 462 TYR B CE2 1 
ATOM   6422  C CZ  . TYR B 2 446 ? 154.772 177.255 167.906 1.00 23.98  ? 462 TYR B CZ  1 
ATOM   6423  O OH  . TYR B 2 446 ? 155.600 176.340 168.508 1.00 26.94  ? 462 TYR B OH  1 
ATOM   6424  N N   . ASN B 2 447 ? 153.657 182.039 168.435 1.00 26.22  ? 463 ASN B N   1 
ATOM   6425  C CA  . ASN B 2 447 ? 154.938 182.530 168.934 1.00 23.53  ? 463 ASN B CA  1 
ATOM   6426  C C   . ASN B 2 447 ? 155.761 181.338 169.398 1.00 25.21  ? 463 ASN B C   1 
ATOM   6427  O O   . ASN B 2 447 ? 155.531 180.817 170.499 1.00 28.93  ? 463 ASN B O   1 
ATOM   6428  C CB  . ASN B 2 447 ? 154.731 183.523 170.081 1.00 21.23  ? 463 ASN B CB  1 
ATOM   6429  C CG  . ASN B 2 447 ? 155.891 184.482 170.239 1.00 23.33  ? 463 ASN B CG  1 
ATOM   6430  O OD1 . ASN B 2 447 ? 156.917 184.345 169.578 1.00 27.96  ? 463 ASN B OD1 1 
ATOM   6431  N ND2 . ASN B 2 447 ? 155.728 185.470 171.108 1.00 24.58  ? 463 ASN B ND2 1 
ATOM   6432  N N   . PRO B 2 448 ? 156.725 180.865 168.603 1.00 24.97  ? 464 PRO B N   1 
ATOM   6433  C CA  . PRO B 2 448 ? 157.435 179.632 168.973 1.00 24.50  ? 464 PRO B CA  1 
ATOM   6434  C C   . PRO B 2 448 ? 158.426 179.808 170.107 1.00 29.03  ? 464 PRO B C   1 
ATOM   6435  O O   . PRO B 2 448 ? 158.800 178.810 170.733 1.00 33.33  ? 464 PRO B O   1 
ATOM   6436  C CB  . PRO B 2 448 ? 158.141 179.217 167.673 1.00 21.81  ? 464 PRO B CB  1 
ATOM   6437  C CG  . PRO B 2 448 ? 157.844 180.274 166.662 1.00 19.79  ? 464 PRO B CG  1 
ATOM   6438  C CD  . PRO B 2 448 ? 157.182 181.425 167.323 1.00 22.32  ? 464 PRO B CD  1 
ATOM   6439  N N   . LEU B 2 449 ? 158.869 181.033 170.391 1.00 27.20  ? 465 LEU B N   1 
ATOM   6440  C CA  . LEU B 2 449 ? 159.766 181.244 171.521 1.00 26.99  ? 465 LEU B CA  1 
ATOM   6441  C C   . LEU B 2 449 ? 159.012 181.205 172.845 1.00 29.19  ? 465 LEU B C   1 
ATOM   6442  O O   . LEU B 2 449 ? 159.547 180.732 173.852 1.00 33.72  ? 465 LEU B O   1 
ATOM   6443  C CB  . LEU B 2 449 ? 160.511 182.569 171.366 1.00 29.71  ? 465 LEU B CB  1 
ATOM   6444  C CG  . LEU B 2 449 ? 161.957 182.472 170.873 1.00 34.03  ? 465 LEU B CG  1 
ATOM   6445  C CD1 . LEU B 2 449 ? 162.069 181.527 169.686 1.00 33.83  ? 465 LEU B CD1 1 
ATOM   6446  C CD2 . LEU B 2 449 ? 162.505 183.844 170.521 1.00 32.61  ? 465 LEU B CD2 1 
ATOM   6447  N N   . LEU B 2 450 ? 157.777 181.699 172.863 1.00 27.22  ? 466 LEU B N   1 
ATOM   6448  C CA  . LEU B 2 450 ? 156.939 181.669 174.052 1.00 27.16  ? 466 LEU B CA  1 
ATOM   6449  C C   . LEU B 2 450 ? 155.976 180.490 174.070 1.00 33.16  ? 466 LEU B C   1 
ATOM   6450  O O   . LEU B 2 450 ? 155.238 180.330 175.046 1.00 38.56  ? 466 LEU B O   1 
ATOM   6451  C CB  . LEU B 2 450 ? 156.154 182.978 174.177 1.00 26.03  ? 466 LEU B CB  1 
ATOM   6452  C CG  . LEU B 2 450 ? 156.962 184.244 174.470 1.00 24.57  ? 466 LEU B CG  1 
ATOM   6453  C CD1 . LEU B 2 450 ? 156.047 185.447 174.597 1.00 23.52  ? 466 LEU B CD1 1 
ATOM   6454  C CD2 . LEU B 2 450 ? 157.791 184.071 175.726 1.00 30.03  ? 466 LEU B CD2 1 
ATOM   6455  N N   . ASP B 2 451 ? 155.967 179.666 173.019 1.00 30.88  ? 467 ASP B N   1 
ATOM   6456  C CA  . ASP B 2 451 ? 155.117 178.475 172.940 1.00 29.60  ? 467 ASP B CA  1 
ATOM   6457  C C   . ASP B 2 451 ? 153.642 178.813 173.155 1.00 34.39  ? 467 ASP B C   1 
ATOM   6458  O O   . ASP B 2 451 ? 152.915 178.089 173.837 1.00 36.63  ? 467 ASP B O   1 
ATOM   6459  C CB  . ASP B 2 451 ? 155.573 177.406 173.935 1.00 33.59  ? 467 ASP B CB  1 
ATOM   6460  C CG  . ASP B 2 451 ? 157.028 177.026 173.756 1.00 40.91  ? 467 ASP B CG  1 
ATOM   6461  O OD1 . ASP B 2 451 ? 157.376 176.487 172.685 1.00 38.82  ? 467 ASP B OD1 1 
ATOM   6462  O OD2 . ASP B 2 451 ? 157.822 177.258 174.689 1.00 44.94  ? 467 ASP B OD2 1 
ATOM   6463  N N   . SER B 2 452 ? 153.190 179.914 172.560 1.00 31.00  ? 468 SER B N   1 
ATOM   6464  C CA  . SER B 2 452 ? 151.839 180.409 172.769 1.00 28.77  ? 468 SER B CA  1 
ATOM   6465  C C   . SER B 2 452 ? 151.179 180.720 171.432 1.00 26.98  ? 468 SER B C   1 
ATOM   6466  O O   . SER B 2 452 ? 151.848 180.927 170.418 1.00 27.30  ? 468 SER B O   1 
ATOM   6467  C CB  . SER B 2 452 ? 151.834 181.658 173.659 1.00 30.76  ? 468 SER B CB  1 
ATOM   6468  O OG  . SER B 2 452 ? 152.724 182.643 173.164 1.00 29.69  ? 468 SER B OG  1 
ATOM   6469  N N   . PHE B 2 453 ? 149.849 180.747 171.448 1.00 27.45  ? 469 PHE B N   1 
ATOM   6470  C CA  . PHE B 2 453 ? 149.041 181.062 170.281 1.00 29.79  ? 469 PHE B CA  1 
ATOM   6471  C C   . PHE B 2 453 ? 148.135 182.249 170.583 1.00 30.92  ? 469 PHE B C   1 
ATOM   6472  O O   . PHE B 2 453 ? 147.905 182.606 171.741 1.00 34.54  ? 469 PHE B O   1 
ATOM   6473  C CB  . PHE B 2 453 ? 148.182 179.865 169.843 1.00 32.49  ? 469 PHE B CB  1 
ATOM   6474  C CG  . PHE B 2 453 ? 148.973 178.636 169.499 1.00 28.08  ? 469 PHE B CG  1 
ATOM   6475  C CD1 . PHE B 2 453 ? 149.299 177.711 170.474 1.00 29.33  ? 469 PHE B CD1 1 
ATOM   6476  C CD2 . PHE B 2 453 ? 149.375 178.398 168.198 1.00 28.29  ? 469 PHE B CD2 1 
ATOM   6477  C CE1 . PHE B 2 453 ? 150.022 176.581 170.161 1.00 28.05  ? 469 PHE B CE1 1 
ATOM   6478  C CE2 . PHE B 2 453 ? 150.095 177.267 167.880 1.00 29.54  ? 469 PHE B CE2 1 
ATOM   6479  C CZ  . PHE B 2 453 ? 150.420 176.360 168.863 1.00 29.20  ? 469 PHE B CZ  1 
ATOM   6480  N N   . THR B 2 454 ? 147.616 182.856 169.518 1.00 32.47  ? 470 THR B N   1 
ATOM   6481  C CA  . THR B 2 454 ? 146.685 183.970 169.633 1.00 36.55  ? 470 THR B CA  1 
ATOM   6482  C C   . THR B 2 454 ? 145.772 183.960 168.417 1.00 41.92  ? 470 THR B C   1 
ATOM   6483  O O   . THR B 2 454 ? 146.254 183.907 167.283 1.00 42.98  ? 470 THR B O   1 
ATOM   6484  C CB  . THR B 2 454 ? 147.429 185.306 169.739 1.00 34.80  ? 470 THR B CB  1 
ATOM   6485  O OG1 . THR B 2 454 ? 147.840 185.521 171.094 1.00 35.54  ? 470 THR B OG1 1 
ATOM   6486  C CG2 . THR B 2 454 ? 146.542 186.455 169.298 1.00 39.77  ? 470 THR B CG2 1 
ATOM   6487  N N   . ARG B 2 455 ? 144.464 184.009 168.653 1.00 44.71  ? 471 ARG B N   1 
ATOM   6488  C CA  . ARG B 2 455 ? 143.471 183.929 167.590 1.00 44.89  ? 471 ARG B CA  1 
ATOM   6489  C C   . ARG B 2 455 ? 142.977 185.319 167.217 1.00 49.04  ? 471 ARG B C   1 
ATOM   6490  O O   . ARG B 2 455 ? 142.618 186.112 168.092 1.00 53.26  ? 471 ARG B O   1 
ATOM   6491  C CB  . ARG B 2 455 ? 142.286 183.058 168.009 1.00 48.21  ? 471 ARG B CB  1 
ATOM   6492  C CG  . ARG B 2 455 ? 142.350 181.631 167.501 1.00 54.80  ? 471 ARG B CG  1 
ATOM   6493  C CD  . ARG B 2 455 ? 141.074 181.250 166.767 1.00 57.49  ? 471 ARG B CD  1 
ATOM   6494  N NE  . ARG B 2 455 ? 141.093 179.868 166.300 1.00 59.75  ? 471 ARG B NE  1 
ATOM   6495  C CZ  . ARG B 2 455 ? 141.030 178.804 167.089 1.00 59.46  ? 471 ARG B CZ  1 
ATOM   6496  N NH1 . ARG B 2 455 ? 140.919 178.920 168.403 1.00 52.29  ? 471 ARG B NH1 1 
ATOM   6497  N NH2 . ARG B 2 455 ? 141.072 177.590 166.546 1.00 56.78  ? 471 ARG B NH2 1 
ATOM   6498  N N   . LEU B 2 456 ? 142.957 185.605 165.919 1.00 51.38  ? 472 LEU B N   1 
ATOM   6499  C CA  . LEU B 2 456 ? 142.352 186.816 165.385 1.00 54.74  ? 472 LEU B CA  1 
ATOM   6500  C C   . LEU B 2 456 ? 141.030 186.447 164.730 1.00 59.97  ? 472 LEU B C   1 
ATOM   6501  O O   . LEU B 2 456 ? 140.989 185.583 163.849 1.00 62.79  ? 472 LEU B O   1 
ATOM   6502  C CB  . LEU B 2 456 ? 143.269 187.507 164.371 1.00 53.98  ? 472 LEU B CB  1 
ATOM   6503  C CG  . LEU B 2 456 ? 144.658 188.011 164.790 1.00 55.84  ? 472 LEU B CG  1 
ATOM   6504  C CD1 . LEU B 2 456 ? 145.680 186.886 164.928 1.00 46.41  ? 472 LEU B CD1 1 
ATOM   6505  C CD2 . LEU B 2 456 ? 145.152 189.063 163.810 1.00 49.87  ? 472 LEU B CD2 1 
ATOM   6506  N N   . CYS B 2 457 ? 139.954 187.097 165.160 1.00 71.79  ? 473 CYS B N   1 
ATOM   6507  C CA  . CYS B 2 457 ? 138.620 186.753 164.687 1.00 77.04  ? 473 CYS B CA  1 
ATOM   6508  C C   . CYS B 2 457 ? 138.388 187.351 163.305 1.00 77.50  ? 473 CYS B C   1 
ATOM   6509  O O   . CYS B 2 457 ? 138.444 188.574 163.131 1.00 77.87  ? 473 CYS B O   1 
ATOM   6510  C CB  . CYS B 2 457 ? 137.563 187.241 165.675 1.00 78.00  ? 473 CYS B CB  1 
ATOM   6511  S SG  . CYS B 2 457 ? 137.788 188.944 166.245 1.00 89.11  ? 473 CYS B SG  1 
ATOM   6512  N N   . LEU B 2 458 ? 138.128 186.490 162.326 1.00 80.20  ? 474 LEU B N   1 
ATOM   6513  C CA  . LEU B 2 458 ? 137.782 186.859 160.962 1.00 88.31  ? 474 LEU B CA  1 
ATOM   6514  C C   . LEU B 2 458 ? 136.271 186.974 160.818 1.00 96.18  ? 474 LEU B C   1 
ATOM   6515  O O   . LEU B 2 458 ? 135.535 186.123 161.331 1.00 97.76  ? 474 LEU B O   1 
ATOM   6516  C CB  . LEU B 2 458 ? 138.311 185.824 159.968 1.00 87.55  ? 474 LEU B CB  1 
ATOM   6517  C CG  . LEU B 2 458 ? 139.504 186.241 159.107 1.00 81.32  ? 474 LEU B CG  1 
ATOM   6518  C CD1 . LEU B 2 458 ? 140.623 186.783 159.975 1.00 70.62  ? 474 LEU B CD1 1 
ATOM   6519  C CD2 . LEU B 2 458 ? 139.997 185.072 158.270 1.00 75.40  ? 474 LEU B CD2 1 
ATOM   6520  N N   . PRO B 2 459 ? 135.781 188.015 160.146 1.00 99.90  ? 475 PRO B N   1 
ATOM   6521  C CA  . PRO B 2 459 ? 134.328 188.199 160.033 1.00 104.37 ? 475 PRO B CA  1 
ATOM   6522  C C   . PRO B 2 459 ? 133.668 187.022 159.330 1.00 109.04 ? 475 PRO B C   1 
ATOM   6523  O O   . PRO B 2 459 ? 134.224 186.435 158.399 1.00 107.13 ? 475 PRO B O   1 
ATOM   6524  C CB  . PRO B 2 459 ? 134.192 189.494 159.222 1.00 102.97 ? 475 PRO B CB  1 
ATOM   6525  C CG  . PRO B 2 459 ? 135.514 189.694 158.567 1.00 98.46  ? 475 PRO B CG  1 
ATOM   6526  C CD  . PRO B 2 459 ? 136.534 189.084 159.471 1.00 96.02  ? 475 PRO B CD  1 
ATOM   6527  N N   . GLU B 2 460 ? 132.463 186.682 159.789 1.00 111.99 ? 476 GLU B N   1 
ATOM   6528  C CA  . GLU B 2 460 ? 131.727 185.520 159.310 1.00 112.86 ? 476 GLU B CA  1 
ATOM   6529  C C   . GLU B 2 460 ? 130.988 185.777 158.002 1.00 113.38 ? 476 GLU B C   1 
ATOM   6530  O O   . GLU B 2 460 ? 130.098 184.996 157.646 1.00 114.59 ? 476 GLU B O   1 
ATOM   6531  C CB  . GLU B 2 460 ? 130.740 185.049 160.381 1.00 112.86 ? 476 GLU B CB  1 
ATOM   6532  C CG  . GLU B 2 460 ? 131.390 184.328 161.549 1.00 114.86 ? 476 GLU B CG  1 
ATOM   6533  C CD  . GLU B 2 460 ? 130.388 183.913 162.608 1.00 115.82 ? 476 GLU B CD  1 
ATOM   6534  O OE1 . GLU B 2 460 ? 129.178 184.148 162.407 1.00 113.89 ? 476 GLU B OE1 1 
ATOM   6535  O OE2 . GLU B 2 460 ? 130.810 183.352 163.641 1.00 113.73 ? 476 GLU B OE2 1 
ATOM   6536  N N   . ALA B 2 461 ? 131.330 186.848 157.283 1.00 112.42 ? 477 ALA B N   1 
ATOM   6537  C CA  . ALA B 2 461 ? 130.645 187.146 156.030 1.00 113.40 ? 477 ALA B CA  1 
ATOM   6538  C C   . ALA B 2 461 ? 130.941 186.104 154.959 1.00 112.79 ? 477 ALA B C   1 
ATOM   6539  O O   . ALA B 2 461 ? 130.144 185.929 154.031 1.00 111.74 ? 477 ALA B O   1 
ATOM   6540  C CB  . ALA B 2 461 ? 131.035 188.539 155.537 1.00 110.62 ? 477 ALA B CB  1 
ATOM   6541  N N   . TRP B 2 462 ? 132.073 185.407 155.065 1.00 111.72 ? 478 TRP B N   1 
ATOM   6542  C CA  . TRP B 2 462 ? 132.482 184.427 154.067 1.00 112.29 ? 478 TRP B CA  1 
ATOM   6543  C C   . TRP B 2 462 ? 132.453 182.999 154.602 1.00 114.92 ? 478 TRP B C   1 
ATOM   6544  O O   . TRP B 2 462 ? 133.084 182.110 154.021 1.00 115.08 ? 478 TRP B O   1 
ATOM   6545  C CB  . TRP B 2 462 ? 133.875 184.765 153.537 1.00 108.93 ? 478 TRP B CB  1 
ATOM   6546  C CG  . TRP B 2 462 ? 134.830 185.211 154.600 1.00 106.75 ? 478 TRP B CG  1 
ATOM   6547  C CD1 . TRP B 2 462 ? 135.290 184.472 155.648 1.00 104.26 ? 478 TRP B CD1 1 
ATOM   6548  C CD2 . TRP B 2 462 ? 135.444 186.499 154.718 1.00 104.13 ? 478 TRP B CD2 1 
ATOM   6549  N NE1 . TRP B 2 462 ? 136.153 185.218 156.412 1.00 101.69 ? 478 TRP B NE1 1 
ATOM   6550  C CE2 . TRP B 2 462 ? 136.264 186.467 155.862 1.00 102.19 ? 478 TRP B CE2 1 
ATOM   6551  C CE3 . TRP B 2 462 ? 135.381 187.676 153.967 1.00 97.25  ? 478 TRP B CE3 1 
ATOM   6552  C CZ2 . TRP B 2 462 ? 137.016 187.565 156.272 1.00 96.76  ? 478 TRP B CZ2 1 
ATOM   6553  C CZ3 . TRP B 2 462 ? 136.126 188.765 154.378 1.00 92.62  ? 478 TRP B CZ3 1 
ATOM   6554  C CH2 . TRP B 2 462 ? 136.933 188.702 155.519 1.00 91.97  ? 478 TRP B CH2 1 
ATOM   6555  N N   . SER B 2 463 ? 131.735 182.759 155.701 1.00 116.64 ? 479 SER B N   1 
ATOM   6556  C CA  . SER B 2 463 ? 131.656 181.417 156.265 1.00 118.71 ? 479 SER B CA  1 
ATOM   6557  C C   . SER B 2 463 ? 130.756 180.488 155.461 1.00 121.78 ? 479 SER B C   1 
ATOM   6558  O O   . SER B 2 463 ? 130.815 179.271 155.667 1.00 121.44 ? 479 SER B O   1 
ATOM   6559  C CB  . SER B 2 463 ? 131.165 181.483 157.712 1.00 115.11 ? 479 SER B CB  1 
ATOM   6560  O OG  . SER B 2 463 ? 129.889 182.096 157.790 1.00 116.12 ? 479 SER B OG  1 
ATOM   6561  N N   . SER B 2 464 ? 129.927 181.026 154.563 1.00 121.08 ? 480 SER B N   1 
ATOM   6562  C CA  . SER B 2 464 ? 129.033 180.181 153.777 1.00 121.38 ? 480 SER B CA  1 
ATOM   6563  C C   . SER B 2 464 ? 129.812 179.249 152.857 1.00 121.76 ? 480 SER B C   1 
ATOM   6564  O O   . SER B 2 464 ? 129.474 178.066 152.732 1.00 120.40 ? 480 SER B O   1 
ATOM   6565  C CB  . SER B 2 464 ? 128.067 181.047 152.970 1.00 119.76 ? 480 SER B CB  1 
ATOM   6566  O OG  . SER B 2 464 ? 128.766 181.876 152.057 1.00 116.62 ? 480 SER B OG  1 
ATOM   6567  N N   . ALA B 2 465 ? 130.857 179.760 152.206 1.00 121.39 ? 481 ALA B N   1 
ATOM   6568  C CA  . ALA B 2 465 ? 131.645 178.964 151.278 1.00 118.07 ? 481 ALA B CA  1 
ATOM   6569  C C   . ALA B 2 465 ? 132.868 178.414 151.989 1.00 115.42 ? 481 ALA B C   1 
ATOM   6570  O O   . ALA B 2 465 ? 133.723 179.201 152.426 1.00 113.44 ? 481 ALA B O   1 
ATOM   6571  C CB  . ALA B 2 465 ? 132.066 179.802 150.076 1.00 111.55 ? 481 ALA B CB  1 
ATOM   6572  N N   . PRO B 2 466 ? 133.004 177.096 152.129 1.00 115.51 ? 482 PRO B N   1 
ATOM   6573  C CA  . PRO B 2 466 ? 134.192 176.529 152.800 1.00 112.76 ? 482 PRO B CA  1 
ATOM   6574  C C   . PRO B 2 466 ? 135.374 176.401 151.846 1.00 109.73 ? 482 PRO B C   1 
ATOM   6575  O O   . PRO B 2 466 ? 135.813 175.310 151.467 1.00 107.10 ? 482 PRO B O   1 
ATOM   6576  C CB  . PRO B 2 466 ? 133.673 175.175 153.295 1.00 113.95 ? 482 PRO B CB  1 
ATOM   6577  C CG  . PRO B 2 466 ? 132.582 174.798 152.327 1.00 114.75 ? 482 PRO B CG  1 
ATOM   6578  C CD  . PRO B 2 466 ? 132.093 176.049 151.636 1.00 115.12 ? 482 PRO B CD  1 
ATOM   6579  N N   . SER B 2 467 ? 135.910 177.547 151.439 1.00 106.71 ? 483 SER B N   1 
ATOM   6580  C CA  . SER B 2 467 ? 137.029 177.593 150.512 1.00 97.96  ? 483 SER B CA  1 
ATOM   6581  C C   . SER B 2 467 ? 138.350 177.697 151.267 1.00 87.20  ? 483 SER B C   1 
ATOM   6582  O O   . SER B 2 467 ? 138.394 178.032 152.453 1.00 87.12  ? 483 SER B O   1 
ATOM   6583  C CB  . SER B 2 467 ? 136.887 178.772 149.550 1.00 97.17  ? 483 SER B CB  1 
ATOM   6584  O OG  . SER B 2 467 ? 136.742 179.990 150.259 1.00 93.91  ? 483 SER B OG  1 
ATOM   6585  N N   . LEU B 2 468 ? 139.434 177.399 150.559 1.00 80.10  ? 484 LEU B N   1 
ATOM   6586  C CA  . LEU B 2 468 ? 140.762 177.525 151.139 1.00 74.63  ? 484 LEU B CA  1 
ATOM   6587  C C   . LEU B 2 468 ? 141.155 178.993 151.248 1.00 73.62  ? 484 LEU B C   1 
ATOM   6588  O O   . LEU B 2 468 ? 140.657 179.849 150.513 1.00 76.03  ? 484 LEU B O   1 
ATOM   6589  C CB  . LEU B 2 468 ? 141.788 176.769 150.298 1.00 72.97  ? 484 LEU B CB  1 
ATOM   6590  C CG  . LEU B 2 468 ? 141.586 175.256 150.221 1.00 79.09  ? 484 LEU B CG  1 
ATOM   6591  C CD1 . LEU B 2 468 ? 142.790 174.582 149.577 1.00 74.13  ? 484 LEU B CD1 1 
ATOM   6592  C CD2 . LEU B 2 468 ? 141.302 174.677 151.599 1.00 76.81  ? 484 LEU B CD2 1 
ATOM   6593  N N   . TRP B 2 469 ? 142.056 179.281 152.183 1.00 65.60  ? 485 TRP B N   1 
ATOM   6594  C CA  . TRP B 2 469 ? 142.523 180.639 152.413 1.00 57.40  ? 485 TRP B CA  1 
ATOM   6595  C C   . TRP B 2 469 ? 144.043 180.629 152.351 1.00 49.29  ? 485 TRP B C   1 
ATOM   6596  O O   . TRP B 2 469 ? 144.680 179.729 152.907 1.00 47.23  ? 485 TRP B O   1 
ATOM   6597  C CB  . TRP B 2 469 ? 142.051 181.161 153.774 1.00 60.40  ? 485 TRP B CB  1 
ATOM   6598  C CG  . TRP B 2 469 ? 140.634 181.667 153.784 1.00 67.01  ? 485 TRP B CG  1 
ATOM   6599  C CD1 . TRP B 2 469 ? 139.518 180.944 154.091 1.00 72.66  ? 485 TRP B CD1 1 
ATOM   6600  C CD2 . TRP B 2 469 ? 140.175 182.982 153.445 1.00 69.22  ? 485 TRP B CD2 1 
ATOM   6601  N NE1 . TRP B 2 469 ? 138.399 181.730 153.986 1.00 80.42  ? 485 TRP B NE1 1 
ATOM   6602  C CE2 . TRP B 2 469 ? 138.775 182.985 153.587 1.00 78.35  ? 485 TRP B CE2 1 
ATOM   6603  C CE3 . TRP B 2 469 ? 140.810 184.154 153.036 1.00 65.30  ? 485 TRP B CE3 1 
ATOM   6604  C CZ2 . TRP B 2 469 ? 138.003 184.115 153.340 1.00 81.19  ? 485 TRP B CZ2 1 
ATOM   6605  C CZ3 . TRP B 2 469 ? 140.043 185.277 152.797 1.00 70.68  ? 485 TRP B CZ3 1 
ATOM   6606  C CH2 . TRP B 2 469 ? 138.654 185.249 152.947 1.00 80.55  ? 485 TRP B CH2 1 
ATOM   6607  N N   . LYS B 2 470 ? 144.623 181.617 151.678 1.00 42.14  ? 486 LYS B N   1 
ATOM   6608  C CA  . LYS B 2 470 ? 146.069 181.750 151.568 1.00 37.02  ? 486 LYS B CA  1 
ATOM   6609  C C   . LYS B 2 470 ? 146.496 183.111 152.094 1.00 36.86  ? 486 LYS B C   1 
ATOM   6610  O O   . LYS B 2 470 ? 145.819 184.116 151.862 1.00 38.81  ? 486 LYS B O   1 
ATOM   6611  C CB  . LYS B 2 470 ? 146.538 181.572 150.122 1.00 37.67  ? 486 LYS B CB  1 
ATOM   6612  C CG  . LYS B 2 470 ? 145.933 180.374 149.417 1.00 37.98  ? 486 LYS B CG  1 
ATOM   6613  C CD  . LYS B 2 470 ? 146.972 179.648 148.585 1.00 31.82  ? 486 LYS B CD  1 
ATOM   6614  C CE  . LYS B 2 470 ? 146.711 178.157 148.565 1.00 31.12  ? 486 LYS B CE  1 
ATOM   6615  N NZ  . LYS B 2 470 ? 145.258 177.858 148.532 1.00 40.56  ? 486 LYS B NZ  1 
ATOM   6616  N N   . ILE B 2 471 ? 147.620 183.142 152.805 1.00 34.49  ? 487 ILE B N   1 
ATOM   6617  C CA  . ILE B 2 471 ? 148.110 184.354 153.447 1.00 33.06  ? 487 ILE B CA  1 
ATOM   6618  C C   . ILE B 2 471 ? 149.538 184.628 153.000 1.00 33.07  ? 487 ILE B C   1 
ATOM   6619  O O   . ILE B 2 471 ? 150.354 183.707 152.879 1.00 33.16  ? 487 ILE B O   1 
ATOM   6620  C CB  . ILE B 2 471 ? 148.033 184.260 154.986 1.00 35.49  ? 487 ILE B CB  1 
ATOM   6621  C CG1 . ILE B 2 471 ? 148.678 182.968 155.481 1.00 32.18  ? 487 ILE B CG1 1 
ATOM   6622  C CG2 . ILE B 2 471 ? 146.598 184.366 155.462 1.00 40.05  ? 487 ILE B CG2 1 
ATOM   6623  C CD1 . ILE B 2 471 ? 148.682 182.849 156.973 1.00 31.16  ? 487 ILE B CD1 1 
ATOM   6624  N N   . ALA B 2 472 ? 149.830 185.901 152.742 1.00 33.15  ? 488 ALA B N   1 
ATOM   6625  C CA  . ALA B 2 472 ? 151.172 186.365 152.438 1.00 32.58  ? 488 ALA B CA  1 
ATOM   6626  C C   . ALA B 2 472 ? 151.399 187.683 153.162 1.00 34.54  ? 488 ALA B C   1 
ATOM   6627  O O   . ALA B 2 472 ? 150.453 188.420 153.444 1.00 40.13  ? 488 ALA B O   1 
ATOM   6628  C CB  . ALA B 2 472 ? 151.387 186.538 150.932 1.00 33.73  ? 488 ALA B CB  1 
ATOM   6629  N N   . SER B 2 473 ? 152.660 187.975 153.462 1.00 34.87  ? 489 SER B N   1 
ATOM   6630  C CA  . SER B 2 473 ? 153.022 189.145 154.245 1.00 42.17  ? 489 SER B CA  1 
ATOM   6631  C C   . SER B 2 473 ? 153.927 190.066 153.440 1.00 53.75  ? 489 SER B C   1 
ATOM   6632  O O   . SER B 2 473 ? 154.682 189.619 152.571 1.00 53.31  ? 489 SER B O   1 
ATOM   6633  C CB  . SER B 2 473 ? 153.725 188.742 155.546 1.00 37.71  ? 489 SER B CB  1 
ATOM   6634  O OG  . SER B 2 473 ? 155.130 188.860 155.426 1.00 37.01  ? 489 SER B OG  1 
ATOM   6635  N N   . CYS B 2 474 ? 153.842 191.363 153.735 1.00 57.70  ? 490 CYS B N   1 
ATOM   6636  C CA  . CYS B 2 474 ? 154.746 192.338 153.128 1.00 61.98  ? 490 CYS B CA  1 
ATOM   6637  C C   . CYS B 2 474 ? 154.808 193.583 154.002 1.00 62.62  ? 490 CYS B C   1 
ATOM   6638  O O   . CYS B 2 474 ? 153.773 194.198 154.280 1.00 61.26  ? 490 CYS B O   1 
ATOM   6639  C CB  . CYS B 2 474 ? 154.307 192.681 151.697 1.00 65.02  ? 490 CYS B CB  1 
ATOM   6640  S SG  . CYS B 2 474 ? 152.861 193.754 151.528 1.00 81.97  ? 490 CYS B SG  1 
ATOM   6641  N N   . ASN B 2 475 ? 156.012 193.903 154.476 1.00 62.15  ? 491 ASN B N   1 
ATOM   6642  C CA  . ASN B 2 475 ? 156.376 195.176 155.109 1.00 64.68  ? 491 ASN B CA  1 
ATOM   6643  C C   . ASN B 2 475 ? 155.261 195.750 155.985 1.00 65.61  ? 491 ASN B C   1 
ATOM   6644  O O   . ASN B 2 475 ? 154.772 196.860 155.778 1.00 73.55  ? 491 ASN B O   1 
ATOM   6645  C CB  . ASN B 2 475 ? 156.840 196.202 154.069 1.00 66.79  ? 491 ASN B CB  1 
ATOM   6646  C CG  . ASN B 2 475 ? 155.915 196.300 152.872 1.00 71.91  ? 491 ASN B CG  1 
ATOM   6647  O OD1 . ASN B 2 475 ? 154.708 196.486 153.014 1.00 72.87  ? 491 ASN B OD1 1 
ATOM   6648  N ND2 . ASN B 2 475 ? 156.484 196.175 151.678 1.00 72.54  ? 491 ASN B ND2 1 
ATOM   6649  N N   . GLY B 2 476 ? 154.868 194.969 156.985 1.00 55.38  ? 492 GLY B N   1 
ATOM   6650  C CA  . GLY B 2 476 ? 154.003 195.465 158.034 1.00 50.67  ? 492 GLY B CA  1 
ATOM   6651  C C   . GLY B 2 476 ? 152.538 195.102 157.943 1.00 53.11  ? 492 GLY B C   1 
ATOM   6652  O O   . GLY B 2 476 ? 151.746 195.621 158.736 1.00 53.16  ? 492 GLY B O   1 
ATOM   6653  N N   . SER B 2 477 ? 152.147 194.238 157.010 1.00 55.94  ? 493 SER B N   1 
ATOM   6654  C CA  . SER B 2 477 ? 150.758 193.809 156.935 1.00 51.03  ? 493 SER B CA  1 
ATOM   6655  C C   . SER B 2 477 ? 150.684 192.426 156.310 1.00 44.54  ? 493 SER B C   1 
ATOM   6656  O O   . SER B 2 477 ? 151.620 191.963 155.654 1.00 42.81  ? 493 SER B O   1 
ATOM   6657  C CB  . SER B 2 477 ? 149.896 194.792 156.137 1.00 53.24  ? 493 SER B CB  1 
ATOM   6658  O OG  . SER B 2 477 ? 148.851 194.108 155.474 1.00 50.78  ? 493 SER B OG  1 
ATOM   6659  N N   . ILE B 2 478 ? 149.546 191.774 156.524 1.00 40.23  ? 494 ILE B N   1 
ATOM   6660  C CA  . ILE B 2 478 ? 149.291 190.425 156.038 1.00 38.20  ? 494 ILE B CA  1 
ATOM   6661  C C   . ILE B 2 478 ? 148.188 190.508 154.993 1.00 38.14  ? 494 ILE B C   1 
ATOM   6662  O O   . ILE B 2 478 ? 147.118 191.070 155.254 1.00 39.74  ? 494 ILE B O   1 
ATOM   6663  C CB  . ILE B 2 478 ? 148.896 189.479 157.183 1.00 38.90  ? 494 ILE B CB  1 
ATOM   6664  C CG1 . ILE B 2 478 ? 150.014 189.401 158.225 1.00 34.15  ? 494 ILE B CG1 1 
ATOM   6665  C CG2 . ILE B 2 478 ? 148.556 188.098 156.647 1.00 37.38  ? 494 ILE B CG2 1 
ATOM   6666  C CD1 . ILE B 2 478 ? 151.074 188.379 157.912 1.00 32.66  ? 494 ILE B CD1 1 
ATOM   6667  N N   . TYR B 2 479 ? 148.448 189.960 153.811 1.00 38.81  ? 495 TYR B N   1 
ATOM   6668  C CA  . TYR B 2 479 ? 147.442 189.838 152.766 1.00 36.05  ? 495 TYR B CA  1 
ATOM   6669  C C   . TYR B 2 479 ? 146.859 188.436 152.784 1.00 37.37  ? 495 TYR B C   1 
ATOM   6670  O O   . TYR B 2 479 ? 147.599 187.450 152.824 1.00 38.91  ? 495 TYR B O   1 
ATOM   6671  C CB  . TYR B 2 479 ? 148.022 190.149 151.388 1.00 37.21  ? 495 TYR B CB  1 
ATOM   6672  C CG  . TYR B 2 479 ? 148.165 191.620 151.118 1.00 43.11  ? 495 TYR B CG  1 
ATOM   6673  C CD1 . TYR B 2 479 ? 147.116 192.343 150.570 1.00 45.45  ? 495 TYR B CD1 1 
ATOM   6674  C CD2 . TYR B 2 479 ? 149.344 192.289 151.403 1.00 45.14  ? 495 TYR B CD2 1 
ATOM   6675  C CE1 . TYR B 2 479 ? 147.234 193.687 150.321 1.00 50.11  ? 495 TYR B CE1 1 
ATOM   6676  C CE2 . TYR B 2 479 ? 149.470 193.635 151.159 1.00 49.45  ? 495 TYR B CE2 1 
ATOM   6677  C CZ  . TYR B 2 479 ? 148.414 194.328 150.615 1.00 55.52  ? 495 TYR B CZ  1 
ATOM   6678  O OH  . TYR B 2 479 ? 148.536 195.672 150.366 1.00 66.24  ? 495 TYR B OH  1 
ATOM   6679  N N   . VAL B 2 480 ? 145.534 188.355 152.751 1.00 37.90  ? 496 VAL B N   1 
ATOM   6680  C CA  . VAL B 2 480 ? 144.810 187.096 152.830 1.00 40.00  ? 496 VAL B CA  1 
ATOM   6681  C C   . VAL B 2 480 ? 144.080 186.901 151.508 1.00 42.67  ? 496 VAL B C   1 
ATOM   6682  O O   . VAL B 2 480 ? 143.350 187.792 151.062 1.00 47.05  ? 496 VAL B O   1 
ATOM   6683  C CB  . VAL B 2 480 ? 143.832 187.089 154.019 1.00 42.53  ? 496 VAL B CB  1 
ATOM   6684  C CG1 . VAL B 2 480 ? 143.432 185.677 154.371 1.00 45.47  ? 496 VAL B CG1 1 
ATOM   6685  C CG2 . VAL B 2 480 ? 144.452 187.781 155.218 1.00 38.77  ? 496 VAL B CG2 1 
ATOM   6686  N N   . PHE B 2 481 ? 144.285 185.744 150.882 1.00 43.18  ? 497 PHE B N   1 
ATOM   6687  C CA  . PHE B 2 481 ? 143.785 185.471 149.542 1.00 44.95  ? 497 PHE B CA  1 
ATOM   6688  C C   . PHE B 2 481 ? 142.740 184.364 149.575 1.00 52.35  ? 497 PHE B C   1 
ATOM   6689  O O   . PHE B 2 481 ? 142.784 183.470 150.425 1.00 56.14  ? 497 PHE B O   1 
ATOM   6690  C CB  . PHE B 2 481 ? 144.923 185.071 148.589 1.00 42.13  ? 497 PHE B CB  1 
ATOM   6691  C CG  . PHE B 2 481 ? 146.018 186.093 148.483 1.00 37.99  ? 497 PHE B CG  1 
ATOM   6692  C CD1 . PHE B 2 481 ? 147.076 186.091 149.373 1.00 36.50  ? 497 PHE B CD1 1 
ATOM   6693  C CD2 . PHE B 2 481 ? 145.995 187.050 147.486 1.00 36.77  ? 497 PHE B CD2 1 
ATOM   6694  C CE1 . PHE B 2 481 ? 148.082 187.029 149.277 1.00 35.50  ? 497 PHE B CE1 1 
ATOM   6695  C CE2 . PHE B 2 481 ? 147.000 187.990 147.384 1.00 37.73  ? 497 PHE B CE2 1 
ATOM   6696  C CZ  . PHE B 2 481 ? 148.043 187.979 148.281 1.00 37.30  ? 497 PHE B CZ  1 
ATOM   6697  N N   . ARG B 2 482 ? 141.803 184.430 148.634 1.00 59.83  ? 498 ARG B N   1 
ATOM   6698  C CA  . ARG B 2 482 ? 140.733 183.450 148.510 1.00 64.88  ? 498 ARG B CA  1 
ATOM   6699  C C   . ARG B 2 482 ? 141.042 182.493 147.367 1.00 74.54  ? 498 ARG B C   1 
ATOM   6700  O O   . ARG B 2 482 ? 141.332 182.929 146.249 1.00 74.70  ? 498 ARG B O   1 
ATOM   6701  C CB  . ARG B 2 482 ? 139.390 184.135 148.263 1.00 67.42  ? 498 ARG B CB  1 
ATOM   6702  C CG  . ARG B 2 482 ? 138.639 184.506 149.523 1.00 74.90  ? 498 ARG B CG  1 
ATOM   6703  C CD  . ARG B 2 482 ? 137.192 184.056 149.446 1.00 84.57  ? 498 ARG B CD  1 
ATOM   6704  N NE  . ARG B 2 482 ? 136.345 185.054 148.805 1.00 90.04  ? 498 ARG B NE  1 
ATOM   6705  C CZ  . ARG B 2 482 ? 135.448 185.794 149.440 1.00 91.84  ? 498 ARG B CZ  1 
ATOM   6706  N NH1 . ARG B 2 482 ? 135.264 185.688 150.745 1.00 91.99  ? 498 ARG B NH1 1 
ATOM   6707  N NH2 . ARG B 2 482 ? 134.718 186.665 148.749 1.00 91.57  ? 498 ARG B NH2 1 
ATOM   6708  N N   . ASP B 2 483 ? 140.979 181.191 147.652 1.00 76.37  ? 499 ASP B N   1 
ATOM   6709  C CA  . ASP B 2 483 ? 141.239 180.190 146.622 1.00 72.82  ? 499 ASP B CA  1 
ATOM   6710  C C   . ASP B 2 483 ? 140.168 180.250 145.536 1.00 79.40  ? 499 ASP B C   1 
ATOM   6711  O O   . ASP B 2 483 ? 140.481 180.369 144.346 1.00 76.23  ? 499 ASP B O   1 
ATOM   6712  C CB  . ASP B 2 483 ? 141.311 178.802 147.276 1.00 74.19  ? 499 ASP B CB  1 
ATOM   6713  C CG  . ASP B 2 483 ? 141.157 177.635 146.289 1.00 80.41  ? 499 ASP B CG  1 
ATOM   6714  O OD1 . ASP B 2 483 ? 141.207 177.818 145.055 1.00 79.74  ? 499 ASP B OD1 1 
ATOM   6715  O OD2 . ASP B 2 483 ? 141.065 176.486 146.772 1.00 77.24  ? 499 ASP B OD2 1 
ATOM   6716  N N   . ARG B 2 484 ? 138.896 180.196 145.930 1.00 86.10  ? 500 ARG B N   1 
ATOM   6717  C CA  . ARG B 2 484 ? 137.785 180.125 144.981 1.00 89.26  ? 500 ARG B CA  1 
ATOM   6718  C C   . ARG B 2 484 ? 137.313 181.541 144.679 1.00 89.73  ? 500 ARG B C   1 
ATOM   6719  O O   . ARG B 2 484 ? 136.456 182.097 145.367 1.00 92.32  ? 500 ARG B O   1 
ATOM   6720  C CB  . ARG B 2 484 ? 136.660 179.261 145.537 1.00 95.68  ? 500 ARG B CB  1 
ATOM   6721  C CG  . ARG B 2 484 ? 135.654 178.802 144.494 1.00 100.83 ? 500 ARG B CG  1 
ATOM   6722  C CD  . ARG B 2 484 ? 134.271 178.603 145.097 1.00 103.27 ? 500 ARG B CD  1 
ATOM   6723  N NE  . ARG B 2 484 ? 133.980 179.570 146.148 1.00 106.93 ? 500 ARG B NE  1 
ATOM   6724  C CZ  . ARG B 2 484 ? 133.407 180.749 145.944 1.00 109.46 ? 500 ARG B CZ  1 
ATOM   6725  N NH1 . ARG B 2 484 ? 133.047 181.142 144.733 1.00 107.83 ? 500 ARG B NH1 1 
ATOM   6726  N NH2 . ARG B 2 484 ? 133.188 181.552 146.981 1.00 110.07 ? 500 ARG B NH2 1 
ATOM   6727  N N   . TYR B 2 485 ? 137.880 182.130 143.630 1.00 90.81  ? 501 TYR B N   1 
ATOM   6728  C CA  . TYR B 2 485 ? 137.508 183.476 143.214 1.00 95.54  ? 501 TYR B CA  1 
ATOM   6729  C C   . TYR B 2 485 ? 136.205 183.428 142.427 1.00 102.67 ? 501 TYR B C   1 
ATOM   6730  O O   . TYR B 2 485 ? 136.104 182.710 141.425 1.00 102.98 ? 501 TYR B O   1 
ATOM   6731  C CB  . TYR B 2 485 ? 138.613 184.101 142.365 1.00 91.25  ? 501 TYR B CB  1 
ATOM   6732  C CG  . TYR B 2 485 ? 139.816 184.573 143.147 1.00 89.94  ? 501 TYR B CG  1 
ATOM   6733  C CD1 . TYR B 2 485 ? 139.715 185.628 144.043 1.00 91.22  ? 501 TYR B CD1 1 
ATOM   6734  C CD2 . TYR B 2 485 ? 141.056 183.972 142.978 1.00 84.23  ? 501 TYR B CD2 1 
ATOM   6735  C CE1 . TYR B 2 485 ? 140.816 186.066 144.756 1.00 85.93  ? 501 TYR B CE1 1 
ATOM   6736  C CE2 . TYR B 2 485 ? 142.162 184.404 143.685 1.00 77.34  ? 501 TYR B CE2 1 
ATOM   6737  C CZ  . TYR B 2 485 ? 142.036 185.450 144.574 1.00 78.04  ? 501 TYR B CZ  1 
ATOM   6738  O OH  . TYR B 2 485 ? 143.133 185.882 145.281 1.00 70.67  ? 501 TYR B OH  1 
ATOM   6739  N N   . LYS B 2 486 ? 135.210 184.187 142.876 1.00 106.55 ? 502 LYS B N   1 
ATOM   6740  C CA  . LYS B 2 486 ? 133.999 184.349 142.091 1.00 110.41 ? 502 LYS B CA  1 
ATOM   6741  C C   . LYS B 2 486 ? 134.285 185.214 140.865 1.00 112.30 ? 502 LYS B C   1 
ATOM   6742  O O   . LYS B 2 486 ? 135.263 185.965 140.817 1.00 109.43 ? 502 LYS B O   1 
ATOM   6743  C CB  . LYS B 2 486 ? 132.884 184.963 142.937 1.00 110.05 ? 502 LYS B CB  1 
ATOM   6744  C CG  . LYS B 2 486 ? 133.335 186.107 143.828 1.00 109.78 ? 502 LYS B CG  1 
ATOM   6745  C CD  . LYS B 2 486 ? 132.533 186.149 145.118 1.00 109.85 ? 502 LYS B CD  1 
ATOM   6746  C CE  . LYS B 2 486 ? 132.697 184.864 145.912 1.00 105.99 ? 502 LYS B CE  1 
ATOM   6747  N NZ  . LYS B 2 486 ? 132.049 184.955 147.249 1.00 102.47 ? 502 LYS B NZ  1 
ATOM   6748  N N   . LYS B 2 487 ? 133.418 185.089 139.862 1.00 116.99 ? 503 LYS B N   1 
ATOM   6749  C CA  . LYS B 2 487 ? 133.650 185.748 138.582 1.00 119.38 ? 503 LYS B CA  1 
ATOM   6750  C C   . LYS B 2 487 ? 133.730 187.261 138.749 1.00 118.38 ? 503 LYS B C   1 
ATOM   6751  O O   . LYS B 2 487 ? 132.865 187.879 139.377 1.00 116.18 ? 503 LYS B O   1 
ATOM   6752  C CB  . LYS B 2 487 ? 132.542 185.386 137.590 1.00 118.47 ? 503 LYS B CB  1 
ATOM   6753  C CG  . LYS B 2 487 ? 132.684 184.009 136.949 1.00 119.88 ? 503 LYS B CG  1 
ATOM   6754  C CD  . LYS B 2 487 ? 132.193 182.896 137.863 1.00 121.53 ? 503 LYS B CD  1 
ATOM   6755  C CE  . LYS B 2 487 ? 130.701 183.017 138.127 1.00 124.71 ? 503 LYS B CE  1 
ATOM   6756  N NZ  . LYS B 2 487 ? 129.909 182.946 136.869 1.00 124.26 ? 503 LYS B NZ  1 
ATOM   6757  N N   . GLY B 2 488 ? 134.774 187.853 138.175 1.00 115.03 ? 504 GLY B N   1 
ATOM   6758  C CA  . GLY B 2 488 ? 134.940 189.299 138.190 1.00 111.68 ? 504 GLY B CA  1 
ATOM   6759  C C   . GLY B 2 488 ? 135.067 189.907 139.569 1.00 112.96 ? 504 GLY B C   1 
ATOM   6760  O O   . GLY B 2 488 ? 134.504 190.979 139.823 1.00 111.54 ? 504 GLY B O   1 
ATOM   6761  N N   . ASP B 2 489 ? 135.805 189.254 140.466 1.00 113.35 ? 505 ASP B N   1 
ATOM   6762  C CA  . ASP B 2 489 ? 135.984 189.737 141.837 1.00 110.19 ? 505 ASP B CA  1 
ATOM   6763  C C   . ASP B 2 489 ? 137.394 189.374 142.295 1.00 105.27 ? 505 ASP B C   1 
ATOM   6764  O O   . ASP B 2 489 ? 137.675 188.210 142.593 1.00 102.78 ? 505 ASP B O   1 
ATOM   6765  C CB  . ASP B 2 489 ? 134.935 189.147 142.773 1.00 109.30 ? 505 ASP B CB  1 
ATOM   6766  C CG  . ASP B 2 489 ? 133.873 190.155 143.177 1.00 107.56 ? 505 ASP B CG  1 
ATOM   6767  O OD1 . ASP B 2 489 ? 133.593 191.083 142.391 1.00 106.41 ? 505 ASP B OD1 1 
ATOM   6768  O OD2 . ASP B 2 489 ? 133.318 190.016 144.287 1.00 104.45 ? 505 ASP B OD2 1 
ATOM   6769  N N   . ALA B 2 490 ? 138.275 190.371 142.351 1.00 103.54 ? 506 ALA B N   1 
ATOM   6770  C CA  . ALA B 2 490 ? 139.621 190.192 142.895 1.00 101.54 ? 506 ALA B CA  1 
ATOM   6771  C C   . ALA B 2 490 ? 139.552 190.432 144.397 1.00 99.37  ? 506 ALA B C   1 
ATOM   6772  O O   . ALA B 2 490 ? 139.821 191.530 144.889 1.00 95.88  ? 506 ALA B O   1 
ATOM   6773  C CB  . ALA B 2 490 ? 140.610 191.132 142.218 1.00 99.39  ? 506 ALA B CB  1 
ATOM   6774  N N   . ASN B 2 491 ? 139.187 189.387 145.139 1.00 95.20  ? 507 ASN B N   1 
ATOM   6775  C CA  . ASN B 2 491 ? 138.927 189.506 146.574 1.00 87.93  ? 507 ASN B CA  1 
ATOM   6776  C C   . ASN B 2 491 ? 140.207 189.204 147.342 1.00 80.12  ? 507 ASN B C   1 
ATOM   6777  O O   . ASN B 2 491 ? 140.547 188.052 147.609 1.00 70.99  ? 507 ASN B O   1 
ATOM   6778  C CB  . ASN B 2 491 ? 137.786 188.586 146.988 1.00 87.28  ? 507 ASN B CB  1 
ATOM   6779  C CG  . ASN B 2 491 ? 136.447 189.297 147.000 1.00 90.37  ? 507 ASN B CG  1 
ATOM   6780  O OD1 . ASN B 2 491 ? 136.358 190.466 147.373 1.00 87.09  ? 507 ASN B OD1 1 
ATOM   6781  N ND2 . ASN B 2 491 ? 135.400 188.598 146.579 1.00 96.11  ? 507 ASN B ND2 1 
ATOM   6782  N N   . THR B 2 492 ? 140.925 190.266 147.696 1.00 78.18  ? 508 THR B N   1 
ATOM   6783  C CA  . THR B 2 492 ? 142.103 190.195 148.547 1.00 68.60  ? 508 THR B CA  1 
ATOM   6784  C C   . THR B 2 492 ? 141.917 191.168 149.701 1.00 66.50  ? 508 THR B C   1 
ATOM   6785  O O   . THR B 2 492 ? 141.531 192.321 149.486 1.00 67.89  ? 508 THR B O   1 
ATOM   6786  C CB  . THR B 2 492 ? 143.377 190.532 147.769 1.00 64.56  ? 508 THR B CB  1 
ATOM   6787  O OG1 . THR B 2 492 ? 143.440 189.732 146.582 1.00 68.68  ? 508 THR B OG1 1 
ATOM   6788  C CG2 . THR B 2 492 ? 144.606 190.263 148.617 1.00 52.95  ? 508 THR B CG2 1 
ATOM   6789  N N   . TYR B 2 493 ? 142.188 190.705 150.916 1.00 60.78  ? 509 TYR B N   1 
ATOM   6790  C CA  . TYR B 2 493 ? 141.969 191.490 152.122 1.00 56.76  ? 509 TYR B CA  1 
ATOM   6791  C C   . TYR B 2 493 ? 143.300 191.788 152.795 1.00 48.96  ? 509 TYR B C   1 
ATOM   6792  O O   . TYR B 2 493 ? 144.211 190.957 152.786 1.00 49.97  ? 509 TYR B O   1 
ATOM   6793  C CB  . TYR B 2 493 ? 141.042 190.753 153.090 1.00 62.36  ? 509 TYR B CB  1 
ATOM   6794  C CG  . TYR B 2 493 ? 139.669 190.488 152.520 1.00 69.01  ? 509 TYR B CG  1 
ATOM   6795  C CD1 . TYR B 2 493 ? 139.431 189.377 151.724 1.00 70.06  ? 509 TYR B CD1 1 
ATOM   6796  C CD2 . TYR B 2 493 ? 138.615 191.356 152.766 1.00 71.68  ? 509 TYR B CD2 1 
ATOM   6797  C CE1 . TYR B 2 493 ? 138.180 189.132 151.196 1.00 78.64  ? 509 TYR B CE1 1 
ATOM   6798  C CE2 . TYR B 2 493 ? 137.361 191.120 152.241 1.00 76.25  ? 509 TYR B CE2 1 
ATOM   6799  C CZ  . TYR B 2 493 ? 137.149 190.007 151.456 1.00 83.02  ? 509 TYR B CZ  1 
ATOM   6800  O OH  . TYR B 2 493 ? 135.900 189.766 150.931 1.00 84.84  ? 509 TYR B OH  1 
ATOM   6801  N N   . LYS B 2 494 ? 143.405 192.978 153.376 1.00 50.83  ? 510 LYS B N   1 
ATOM   6802  C CA  . LYS B 2 494 ? 144.619 193.435 154.038 1.00 50.01  ? 510 LYS B CA  1 
ATOM   6803  C C   . LYS B 2 494 ? 144.380 193.457 155.541 1.00 52.25  ? 510 LYS B C   1 
ATOM   6804  O O   . LYS B 2 494 ? 143.477 194.153 156.017 1.00 56.54  ? 510 LYS B O   1 
ATOM   6805  C CB  . LYS B 2 494 ? 145.022 194.819 153.534 1.00 54.49  ? 510 LYS B CB  1 
ATOM   6806  C CG  . LYS B 2 494 ? 146.486 195.150 153.727 1.00 53.25  ? 510 LYS B CG  1 
ATOM   6807  C CD  . LYS B 2 494 ? 146.676 196.612 154.076 1.00 60.88  ? 510 LYS B CD  1 
ATOM   6808  C CE  . LYS B 2 494 ? 146.182 197.512 152.959 1.00 66.52  ? 510 LYS B CE  1 
ATOM   6809  N NZ  . LYS B 2 494 ? 147.119 198.639 152.708 1.00 70.65  ? 510 LYS B NZ  1 
ATOM   6810  N N   . LEU B 2 495 ? 145.189 192.706 156.281 1.00 48.16  ? 511 LEU B N   1 
ATOM   6811  C CA  . LEU B 2 495 ? 145.048 192.587 157.725 1.00 44.33  ? 511 LEU B CA  1 
ATOM   6812  C C   . LEU B 2 495 ? 146.115 193.417 158.424 1.00 43.25  ? 511 LEU B C   1 
ATOM   6813  O O   . LEU B 2 495 ? 147.293 193.354 158.061 1.00 46.13  ? 511 LEU B O   1 
ATOM   6814  C CB  . LEU B 2 495 ? 145.157 191.128 158.167 1.00 45.18  ? 511 LEU B CB  1 
ATOM   6815  C CG  . LEU B 2 495 ? 145.314 190.916 159.675 1.00 46.23  ? 511 LEU B CG  1 
ATOM   6816  C CD1 . LEU B 2 495 ? 143.966 190.680 160.337 1.00 51.82  ? 511 LEU B CD1 1 
ATOM   6817  C CD2 . LEU B 2 495 ? 146.276 189.776 159.972 1.00 41.11  ? 511 LEU B CD2 1 
ATOM   6818  N N   . ASP B 2 496 ? 145.698 194.189 159.422 1.00 45.46  ? 512 ASP B N   1 
ATOM   6819  C CA  . ASP B 2 496 ? 146.629 194.909 160.281 1.00 42.24  ? 512 ASP B CA  1 
ATOM   6820  C C   . ASP B 2 496 ? 146.703 194.193 161.621 1.00 42.50  ? 512 ASP B C   1 
ATOM   6821  O O   . ASP B 2 496 ? 145.730 194.234 162.389 1.00 45.03  ? 512 ASP B O   1 
ATOM   6822  C CB  . ASP B 2 496 ? 146.186 196.360 160.469 1.00 42.17  ? 512 ASP B CB  1 
ATOM   6823  C CG  . ASP B 2 496 ? 147.057 197.111 161.450 1.00 44.77  ? 512 ASP B CG  1 
ATOM   6824  O OD1 . ASP B 2 496 ? 148.283 197.178 161.229 1.00 45.59  ? 512 ASP B OD1 1 
ATOM   6825  O OD2 . ASP B 2 496 ? 146.515 197.643 162.440 1.00 46.98  ? 512 ASP B OD2 1 
ATOM   6826  N N   . PRO B 2 497 ? 147.812 193.521 161.941 1.00 42.34  ? 513 PRO B N   1 
ATOM   6827  C CA  . PRO B 2 497 ? 147.844 192.696 163.161 1.00 36.02  ? 513 PRO B CA  1 
ATOM   6828  C C   . PRO B 2 497 ? 147.641 193.479 164.446 1.00 37.20  ? 513 PRO B C   1 
ATOM   6829  O O   . PRO B 2 497 ? 147.095 192.931 165.411 1.00 39.05  ? 513 PRO B O   1 
ATOM   6830  C CB  . PRO B 2 497 ? 149.237 192.050 163.107 1.00 31.33  ? 513 PRO B CB  1 
ATOM   6831  C CG  . PRO B 2 497 ? 149.683 192.190 161.688 1.00 32.08  ? 513 PRO B CG  1 
ATOM   6832  C CD  . PRO B 2 497 ? 149.081 193.462 161.200 1.00 39.73  ? 513 PRO B CD  1 
ATOM   6833  N N   . ALA B 2 498 ? 148.070 194.743 164.491 1.00 35.47  ? 514 ALA B N   1 
ATOM   6834  C CA  . ALA B 2 498 ? 147.957 195.521 165.721 1.00 33.29  ? 514 ALA B CA  1 
ATOM   6835  C C   . ALA B 2 498 ? 146.501 195.745 166.112 1.00 40.46  ? 514 ALA B C   1 
ATOM   6836  O O   . ALA B 2 498 ? 146.146 195.639 167.291 1.00 42.51  ? 514 ALA B O   1 
ATOM   6837  C CB  . ALA B 2 498 ? 148.680 196.856 165.563 1.00 30.42  ? 514 ALA B CB  1 
ATOM   6838  N N   . THR B 2 499 ? 145.644 196.057 165.141 1.00 42.77  ? 515 THR B N   1 
ATOM   6839  C CA  . THR B 2 499 ? 144.237 196.330 165.402 1.00 42.73  ? 515 THR B CA  1 
ATOM   6840  C C   . THR B 2 499 ? 143.306 195.233 164.902 1.00 44.16  ? 515 THR B C   1 
ATOM   6841  O O   . THR B 2 499 ? 142.099 195.309 165.155 1.00 46.44  ? 515 THR B O   1 
ATOM   6842  C CB  . THR B 2 499 ? 143.830 197.669 164.777 1.00 43.01  ? 515 THR B CB  1 
ATOM   6843  O OG1 . THR B 2 499 ? 143.631 197.503 163.369 1.00 47.36  ? 515 THR B OG1 1 
ATOM   6844  C CG2 . THR B 2 499 ? 144.904 198.715 165.012 1.00 40.27  ? 515 THR B CG2 1 
ATOM   6845  N N   . SER B 2 500 ? 143.831 194.222 164.208 1.00 44.41  ? 516 SER B N   1 
ATOM   6846  C CA  . SER B 2 500 ? 143.035 193.096 163.713 1.00 49.85  ? 516 SER B CA  1 
ATOM   6847  C C   . SER B 2 500 ? 141.872 193.565 162.841 1.00 54.39  ? 516 SER B C   1 
ATOM   6848  O O   . SER B 2 500 ? 140.757 193.047 162.930 1.00 57.60  ? 516 SER B O   1 
ATOM   6849  C CB  . SER B 2 500 ? 142.531 192.228 164.868 1.00 53.04  ? 516 SER B CB  1 
ATOM   6850  O OG  . SER B 2 500 ? 143.596 191.843 165.719 1.00 53.82  ? 516 SER B OG  1 
ATOM   6851  N N   . ALA B 2 501 ? 142.132 194.550 161.987 1.00 55.19  ? 517 ALA B N   1 
ATOM   6852  C CA  . ALA B 2 501 ? 141.119 195.126 161.112 1.00 56.60  ? 517 ALA B CA  1 
ATOM   6853  C C   . ALA B 2 501 ? 141.447 194.770 159.670 1.00 60.43  ? 517 ALA B C   1 
ATOM   6854  O O   . ALA B 2 501 ? 142.540 195.080 159.185 1.00 58.09  ? 517 ALA B O   1 
ATOM   6855  C CB  . ALA B 2 501 ? 141.043 196.642 161.286 1.00 56.82  ? 517 ALA B CB  1 
ATOM   6856  N N   . VAL B 2 502 ? 140.499 194.134 158.988 1.00 63.45  ? 518 VAL B N   1 
ATOM   6857  C CA  . VAL B 2 502 ? 140.662 193.740 157.595 1.00 61.45  ? 518 VAL B CA  1 
ATOM   6858  C C   . VAL B 2 502 ? 140.072 194.822 156.703 1.00 63.22  ? 518 VAL B C   1 
ATOM   6859  O O   . VAL B 2 502 ? 139.246 195.634 157.133 1.00 65.70  ? 518 VAL B O   1 
ATOM   6860  C CB  . VAL B 2 502 ? 140.012 192.369 157.316 1.00 58.51  ? 518 VAL B CB  1 
ATOM   6861  C CG1 . VAL B 2 502 ? 140.394 191.375 158.399 1.00 57.42  ? 518 VAL B CG1 1 
ATOM   6862  C CG2 . VAL B 2 502 ? 138.502 192.507 157.223 1.00 63.06  ? 518 VAL B CG2 1 
ATOM   6863  N N   . THR B 2 503 ? 140.506 194.837 155.445 1.00 63.86  ? 519 THR B N   1 
ATOM   6864  C CA  . THR B 2 503 ? 140.067 195.847 154.492 1.00 67.02  ? 519 THR B CA  1 
ATOM   6865  C C   . THR B 2 503 ? 140.210 195.293 153.083 1.00 66.42  ? 519 THR B C   1 
ATOM   6866  O O   . THR B 2 503 ? 141.276 194.785 152.724 1.00 67.30  ? 519 THR B O   1 
ATOM   6867  C CB  . THR B 2 503 ? 140.881 197.137 154.644 1.00 67.20  ? 519 THR B CB  1 
ATOM   6868  O OG1 . THR B 2 503 ? 140.528 197.783 155.873 1.00 65.85  ? 519 THR B OG1 1 
ATOM   6869  C CG2 . THR B 2 503 ? 140.612 198.085 153.486 1.00 66.89  ? 519 THR B CG2 1 
ATOM   6870  N N   . VAL B 2 504 ? 139.140 195.392 152.293 1.00 68.04  ? 520 VAL B N   1 
ATOM   6871  C CA  . VAL B 2 504 ? 139.173 194.902 150.921 1.00 71.31  ? 520 VAL B CA  1 
ATOM   6872  C C   . VAL B 2 504 ? 140.130 195.754 150.102 1.00 73.35  ? 520 VAL B C   1 
ATOM   6873  O O   . VAL B 2 504 ? 140.069 196.990 150.133 1.00 74.97  ? 520 VAL B O   1 
ATOM   6874  C CB  . VAL B 2 504 ? 137.765 194.910 150.309 1.00 73.26  ? 520 VAL B CB  1 
ATOM   6875  C CG1 . VAL B 2 504 ? 137.722 194.026 149.074 1.00 76.10  ? 520 VAL B CG1 1 
ATOM   6876  C CG2 . VAL B 2 504 ? 136.737 194.459 151.334 1.00 71.51  ? 520 VAL B CG2 1 
ATOM   6877  N N   . THR B 2 505 ? 141.016 195.098 149.360 1.00 74.53  ? 521 THR B N   1 
ATOM   6878  C CA  . THR B 2 505 ? 142.021 195.773 148.556 1.00 78.50  ? 521 THR B CA  1 
ATOM   6879  C C   . THR B 2 505 ? 141.735 195.576 147.073 1.00 88.33  ? 521 THR B C   1 
ATOM   6880  O O   . THR B 2 505 ? 141.124 194.584 146.665 1.00 89.95  ? 521 THR B O   1 
ATOM   6881  C CB  . THR B 2 505 ? 143.425 195.256 148.876 1.00 75.51  ? 521 THR B CB  1 
ATOM   6882  O OG1 . THR B 2 505 ? 143.398 193.827 148.970 1.00 73.47  ? 521 THR B OG1 1 
ATOM   6883  C CG2 . THR B 2 505 ? 143.916 195.835 150.190 1.00 68.94  ? 521 THR B CG2 1 
ATOM   6884  N N   . ARG B 2 506 ? 142.184 196.535 146.273 1.00 92.17  ? 522 ARG B N   1 
ATOM   6885  C CA  . ARG B 2 506 ? 142.058 196.491 144.824 1.00 100.37 ? 522 ARG B CA  1 
ATOM   6886  C C   . ARG B 2 506 ? 143.453 196.536 144.198 1.00 100.88 ? 522 ARG B C   1 
ATOM   6887  O O   . ARG B 2 506 ? 144.472 196.479 144.893 1.00 96.04  ? 522 ARG B O   1 
ATOM   6888  C CB  . ARG B 2 506 ? 141.170 197.636 144.333 1.00 100.11 ? 522 ARG B CB  1 
ATOM   6889  C CG  . ARG B 2 506 ? 139.696 197.453 144.658 1.00 101.36 ? 522 ARG B CG  1 
ATOM   6890  C CD  . ARG B 2 506 ? 138.988 196.656 143.575 1.00 105.51 ? 522 ARG B CD  1 
ATOM   6891  N NE  . ARG B 2 506 ? 137.726 196.095 144.043 1.00 108.52 ? 522 ARG B NE  1 
ATOM   6892  C CZ  . ARG B 2 506 ? 137.616 194.950 144.703 1.00 106.36 ? 522 ARG B CZ  1 
ATOM   6893  N NH1 . ARG B 2 506 ? 138.676 194.214 144.992 1.00 104.15 ? 522 ARG B NH1 1 
ATOM   6894  N NH2 . ARG B 2 506 ? 136.411 194.533 145.082 1.00 105.13 ? 522 ARG B NH2 1 
ATOM   6895  N N   . GLY B 2 507 ? 143.494 196.637 142.872 1.00 101.21 ? 523 GLY B N   1 
ATOM   6896  C CA  . GLY B 2 507 ? 144.743 196.709 142.146 1.00 99.45  ? 523 GLY B CA  1 
ATOM   6897  C C   . GLY B 2 507 ? 145.194 195.420 141.496 1.00 99.55  ? 523 GLY B C   1 
ATOM   6898  O O   . GLY B 2 507 ? 146.278 195.395 140.900 1.00 92.68  ? 523 GLY B O   1 
ATOM   6899  N N   . ILE B 2 508 ? 144.407 194.353 141.589 1.00 101.60 ? 524 ILE B N   1 
ATOM   6900  C CA  . ILE B 2 508 ? 144.713 193.080 140.946 1.00 101.03 ? 524 ILE B CA  1 
ATOM   6901  C C   . ILE B 2 508 ? 143.772 192.926 139.761 1.00 102.44 ? 524 ILE B C   1 
ATOM   6902  O O   . ILE B 2 508 ? 142.548 192.883 139.933 1.00 102.91 ? 524 ILE B O   1 
ATOM   6903  C CB  . ILE B 2 508 ? 144.574 191.901 141.921 1.00 99.76  ? 524 ILE B CB  1 
ATOM   6904  C CG1 . ILE B 2 508 ? 145.683 191.943 142.975 1.00 89.92  ? 524 ILE B CG1 1 
ATOM   6905  C CG2 . ILE B 2 508 ? 144.603 190.582 141.166 1.00 99.03  ? 524 ILE B CG2 1 
ATOM   6906  C CD1 . ILE B 2 508 ? 147.073 191.823 142.402 1.00 78.16  ? 524 ILE B CD1 1 
ATOM   6907  N N   . LYS B 2 509 ? 144.339 192.845 138.560 1.00 100.97 ? 525 LYS B N   1 
ATOM   6908  C CA  . LYS B 2 509 ? 143.567 192.791 137.326 1.00 104.76 ? 525 LYS B CA  1 
ATOM   6909  C C   . LYS B 2 509 ? 143.980 191.598 136.471 1.00 103.00 ? 525 LYS B C   1 
ATOM   6910  O O   . LYS B 2 509 ? 143.985 191.659 135.239 1.00 103.79 ? 525 LYS B O   1 
ATOM   6911  C CB  . LYS B 2 509 ? 143.705 194.097 136.546 1.00 107.88 ? 525 LYS B CB  1 
ATOM   6912  C CG  . LYS B 2 509 ? 142.566 194.372 135.573 1.00 106.44 ? 525 LYS B CG  1 
ATOM   6913  C CD  . LYS B 2 509 ? 141.214 194.244 136.255 1.00 104.30 ? 525 LYS B CD  1 
ATOM   6914  C CE  . LYS B 2 509 ? 140.117 193.961 135.243 1.00 107.91 ? 525 LYS B CE  1 
ATOM   6915  N NZ  . LYS B 2 509 ? 140.079 192.523 134.861 1.00 106.11 ? 525 LYS B NZ  1 
ATOM   6916  N N   . VAL B 2 510 ? 144.338 190.493 137.118 1.00 100.88 ? 526 VAL B N   1 
ATOM   6917  C CA  . VAL B 2 510 ? 144.627 189.236 136.437 1.00 99.53  ? 526 VAL B CA  1 
ATOM   6918  C C   . VAL B 2 510 ? 143.600 188.218 136.908 1.00 97.81  ? 526 VAL B C   1 
ATOM   6919  O O   . VAL B 2 510 ? 143.602 187.824 138.081 1.00 94.45  ? 526 VAL B O   1 
ATOM   6920  C CB  . VAL B 2 510 ? 146.058 188.748 136.709 1.00 89.97  ? 526 VAL B CB  1 
ATOM   6921  C CG1 . VAL B 2 510 ? 146.364 187.520 135.871 1.00 86.64  ? 526 VAL B CG1 1 
ATOM   6922  C CG2 . VAL B 2 510 ? 147.055 189.850 136.412 1.00 83.27  ? 526 VAL B CG2 1 
ATOM   6923  N N   . LEU B 2 511 ? 142.728 187.792 135.997 1.00 99.08  ? 527 LEU B N   1 
ATOM   6924  C CA  . LEU B 2 511 ? 141.611 186.915 136.343 1.00 100.81 ? 527 LEU B CA  1 
ATOM   6925  C C   . LEU B 2 511 ? 142.144 185.502 136.536 1.00 96.92  ? 527 LEU B C   1 
ATOM   6926  O O   . LEU B 2 511 ? 142.207 184.700 135.605 1.00 98.25  ? 527 LEU B O   1 
ATOM   6927  C CB  . LEU B 2 511 ? 140.532 186.966 135.267 1.00 103.12 ? 527 LEU B CB  1 
ATOM   6928  C CG  . LEU B 2 511 ? 139.322 186.048 135.463 1.00 103.59 ? 527 LEU B CG  1 
ATOM   6929  C CD1 . LEU B 2 511 ? 138.348 186.653 136.461 1.00 102.99 ? 527 LEU B CD1 1 
ATOM   6930  C CD2 . LEU B 2 511 ? 138.633 185.773 134.137 1.00 102.45 ? 527 LEU B CD2 1 
ATOM   6931  N N   . LEU B 2 512 ? 142.539 185.196 137.768 1.00 91.00  ? 528 LEU B N   1 
ATOM   6932  C CA  . LEU B 2 512 ? 143.006 183.864 138.142 1.00 83.15  ? 528 LEU B CA  1 
ATOM   6933  C C   . LEU B 2 512 ? 141.828 183.120 138.760 1.00 83.43  ? 528 LEU B C   1 
ATOM   6934  O O   . LEU B 2 512 ? 141.467 183.358 139.915 1.00 83.38  ? 528 LEU B O   1 
ATOM   6935  C CB  . LEU B 2 512 ? 144.185 183.954 139.105 1.00 76.27  ? 528 LEU B CB  1 
ATOM   6936  C CG  . LEU B 2 512 ? 145.539 183.460 138.595 1.00 67.00  ? 528 LEU B CG  1 
ATOM   6937  C CD1 . LEU B 2 512 ? 145.863 184.072 137.249 1.00 78.87  ? 528 LEU B CD1 1 
ATOM   6938  C CD2 . LEU B 2 512 ? 146.620 183.793 139.596 1.00 50.22  ? 528 LEU B CD2 1 
ATOM   6939  N N   . THR B 2 513 ? 141.223 182.222 137.980 1.00 86.19  ? 529 THR B N   1 
ATOM   6940  C CA  . THR B 2 513 ? 140.079 181.463 138.474 1.00 85.98  ? 529 THR B CA  1 
ATOM   6941  C C   . THR B 2 513 ? 140.472 180.565 139.641 1.00 77.94  ? 529 THR B C   1 
ATOM   6942  O O   . THR B 2 513 ? 139.725 180.442 140.618 1.00 79.91  ? 529 THR B O   1 
ATOM   6943  C CB  . THR B 2 513 ? 139.469 180.636 137.344 1.00 89.49  ? 529 THR B CB  1 
ATOM   6944  O OG1 . THR B 2 513 ? 140.517 180.052 136.559 1.00 88.11  ? 529 THR B OG1 1 
ATOM   6945  C CG2 . THR B 2 513 ? 138.606 181.513 136.451 1.00 93.39  ? 529 THR B CG2 1 
ATOM   6946  N N   . ASN B 2 514 ? 141.636 179.930 139.556 1.00 74.59  ? 530 ASN B N   1 
ATOM   6947  C CA  . ASN B 2 514 ? 142.144 179.065 140.609 1.00 71.19  ? 530 ASN B CA  1 
ATOM   6948  C C   . ASN B 2 514 ? 143.463 179.614 141.128 1.00 62.59  ? 530 ASN B C   1 
ATOM   6949  O O   . ASN B 2 514 ? 144.305 180.072 140.350 1.00 61.91  ? 530 ASN B O   1 
ATOM   6950  C CB  . ASN B 2 514 ? 142.339 177.632 140.106 1.00 73.37  ? 530 ASN B CB  1 
ATOM   6951  C CG  . ASN B 2 514 ? 141.240 176.697 140.569 1.00 78.58  ? 530 ASN B CG  1 
ATOM   6952  O OD1 . ASN B 2 514 ? 140.681 176.866 141.651 1.00 79.30  ? 530 ASN B OD1 1 
ATOM   6953  N ND2 . ASN B 2 514 ? 140.925 175.702 139.747 1.00 80.09  ? 530 ASN B ND2 1 
ATOM   6954  N N   . LEU B 2 515 ? 143.635 179.572 142.444 1.00 55.59  ? 531 LEU B N   1 
ATOM   6955  C CA  . LEU B 2 515 ? 144.872 179.980 143.101 1.00 44.56  ? 531 LEU B CA  1 
ATOM   6956  C C   . LEU B 2 515 ? 145.493 178.729 143.710 1.00 41.23  ? 531 LEU B C   1 
ATOM   6957  O O   . LEU B 2 515 ? 145.041 178.244 144.750 1.00 44.20  ? 531 LEU B O   1 
ATOM   6958  C CB  . LEU B 2 515 ? 144.607 181.051 144.153 1.00 50.19  ? 531 LEU B CB  1 
ATOM   6959  C CG  . LEU B 2 515 ? 145.700 182.100 144.353 1.00 45.88  ? 531 LEU B CG  1 
ATOM   6960  C CD1 . LEU B 2 515 ? 145.875 182.931 143.099 1.00 45.62  ? 531 LEU B CD1 1 
ATOM   6961  C CD2 . LEU B 2 515 ? 145.361 182.985 145.534 1.00 47.86  ? 531 LEU B CD2 1 
ATOM   6962  N N   . GLN B 2 516 ? 146.529 178.207 143.055 1.00 35.86  ? 532 GLN B N   1 
ATOM   6963  C CA  . GLN B 2 516 ? 147.141 176.964 143.506 1.00 28.24  ? 532 GLN B CA  1 
ATOM   6964  C C   . GLN B 2 516 ? 148.227 177.211 144.546 1.00 29.02  ? 532 GLN B C   1 
ATOM   6965  O O   . GLN B 2 516 ? 148.309 176.484 145.542 1.00 29.52  ? 532 GLN B O   1 
ATOM   6966  C CB  . GLN B 2 516 ? 147.712 176.202 142.311 1.00 29.32  ? 532 GLN B CB  1 
ATOM   6967  C CG  . GLN B 2 516 ? 147.840 174.708 142.533 1.00 33.40  ? 532 GLN B CG  1 
ATOM   6968  C CD  . GLN B 2 516 ? 148.599 174.019 141.418 1.00 40.57  ? 532 GLN B CD  1 
ATOM   6969  O OE1 . GLN B 2 516 ? 149.105 174.669 140.504 1.00 42.67  ? 532 GLN B OE1 1 
ATOM   6970  N NE2 . GLN B 2 516 ? 148.685 172.696 141.489 1.00 36.86  ? 532 GLN B NE2 1 
ATOM   6971  N N   . PHE B 2 517 ? 149.066 178.221 144.334 1.00 28.44  ? 533 PHE B N   1 
ATOM   6972  C CA  . PHE B 2 517 ? 150.176 178.508 145.228 1.00 25.61  ? 533 PHE B CA  1 
ATOM   6973  C C   . PHE B 2 517 ? 150.271 180.006 145.472 1.00 26.13  ? 533 PHE B C   1 
ATOM   6974  O O   . PHE B 2 517 ? 150.067 180.806 144.556 1.00 25.61  ? 533 PHE B O   1 
ATOM   6975  C CB  . PHE B 2 517 ? 151.506 177.997 144.656 1.00 25.09  ? 533 PHE B CB  1 
ATOM   6976  C CG  . PHE B 2 517 ? 151.584 176.502 144.530 1.00 23.57  ? 533 PHE B CG  1 
ATOM   6977  C CD1 . PHE B 2 517 ? 151.949 175.722 145.611 1.00 21.37  ? 533 PHE B CD1 1 
ATOM   6978  C CD2 . PHE B 2 517 ? 151.304 175.879 143.328 1.00 23.26  ? 533 PHE B CD2 1 
ATOM   6979  C CE1 . PHE B 2 517 ? 152.023 174.352 145.500 1.00 19.78  ? 533 PHE B CE1 1 
ATOM   6980  C CE2 . PHE B 2 517 ? 151.378 174.509 143.212 1.00 22.12  ? 533 PHE B CE2 1 
ATOM   6981  C CZ  . PHE B 2 517 ? 151.736 173.745 144.299 1.00 22.06  ? 533 PHE B CZ  1 
ATOM   6982  N N   . VAL B 2 518 ? 150.573 180.374 146.715 1.00 27.75  ? 534 VAL B N   1 
ATOM   6983  C CA  . VAL B 2 518 ? 150.938 181.737 147.088 1.00 24.22  ? 534 VAL B CA  1 
ATOM   6984  C C   . VAL B 2 518 ? 152.263 181.636 147.829 1.00 23.31  ? 534 VAL B C   1 
ATOM   6985  O O   . VAL B 2 518 ? 152.326 181.047 148.914 1.00 22.10  ? 534 VAL B O   1 
ATOM   6986  C CB  . VAL B 2 518 ? 149.872 182.417 147.958 1.00 25.68  ? 534 VAL B CB  1 
ATOM   6987  C CG1 . VAL B 2 518 ? 150.376 183.752 148.467 1.00 27.14  ? 534 VAL B CG1 1 
ATOM   6988  C CG2 . VAL B 2 518 ? 148.589 182.603 147.175 1.00 26.25  ? 534 VAL B CG2 1 
ATOM   6989  N N   . LEU B 2 519 ? 153.318 182.205 147.251 1.00 25.04  ? 535 LEU B N   1 
ATOM   6990  C CA  . LEU B 2 519 ? 154.679 182.027 147.747 1.00 25.93  ? 535 LEU B CA  1 
ATOM   6991  C C   . LEU B 2 519 ? 155.171 183.340 148.343 1.00 24.11  ? 535 LEU B C   1 
ATOM   6992  O O   . LEU B 2 519 ? 155.399 184.311 147.614 1.00 25.58  ? 535 LEU B O   1 
ATOM   6993  C CB  . LEU B 2 519 ? 155.607 181.550 146.631 1.00 25.11  ? 535 LEU B CB  1 
ATOM   6994  C CG  . LEU B 2 519 ? 155.396 180.149 146.047 1.00 19.36  ? 535 LEU B CG  1 
ATOM   6995  C CD1 . LEU B 2 519 ? 154.896 179.174 147.096 1.00 16.88  ? 535 LEU B CD1 1 
ATOM   6996  C CD2 . LEU B 2 519 ? 154.455 180.189 144.858 1.00 21.55  ? 535 LEU B CD2 1 
ATOM   6997  N N   . ALA B 2 520 ? 155.349 183.353 149.662 1.00 27.36  ? 536 ALA B N   1 
ATOM   6998  C CA  . ALA B 2 520 ? 155.811 184.522 150.409 1.00 29.39  ? 536 ALA B CA  1 
ATOM   6999  C C   . ALA B 2 520 ? 155.025 185.783 150.066 1.00 38.42  ? 536 ALA B C   1 
ATOM   7000  O O   . ALA B 2 520 ? 155.257 186.844 150.645 1.00 43.00  ? 536 ALA B O   1 
ATOM   7001  C CB  . ALA B 2 520 ? 157.290 184.746 150.173 1.00 24.20  ? 536 ALA B CB  1 
ATOM   7002  N N   . MET C 3 21  ? 154.887 142.973 143.079 1.00 51.86  ? 1   MET D N   1 
ATOM   7003  C CA  . MET C 3 21  ? 155.110 141.784 142.266 1.00 54.75  ? 1   MET D CA  1 
ATOM   7004  C C   . MET C 3 21  ? 153.848 140.932 142.183 1.00 61.15  ? 1   MET D C   1 
ATOM   7005  O O   . MET C 3 21  ? 153.382 140.392 143.188 1.00 64.87  ? 1   MET D O   1 
ATOM   7006  C CB  . MET C 3 21  ? 156.267 140.959 142.830 1.00 51.52  ? 1   MET D CB  1 
ATOM   7007  C CG  . MET C 3 21  ? 157.563 141.121 142.059 1.00 54.64  ? 1   MET D CG  1 
ATOM   7008  S SD  . MET C 3 21  ? 157.326 140.998 140.277 1.00 55.77  ? 1   MET D SD  1 
ATOM   7009  C CE  . MET C 3 21  ? 158.710 141.969 139.690 1.00 31.99  ? 1   MET D CE  1 
ATOM   7010  N N   . ARG C 3 22  ? 153.302 140.814 140.977 1.00 58.10  ? 2   ARG D N   1 
ATOM   7011  C CA  . ARG C 3 22  ? 152.072 140.073 140.737 1.00 54.60  ? 2   ARG D CA  1 
ATOM   7012  C C   . ARG C 3 22  ? 152.394 138.751 140.054 1.00 51.95  ? 2   ARG D C   1 
ATOM   7013  O O   . ARG C 3 22  ? 153.062 138.730 139.015 1.00 52.68  ? 2   ARG D O   1 
ATOM   7014  C CB  . ARG C 3 22  ? 151.108 140.898 139.884 1.00 52.03  ? 2   ARG D CB  1 
ATOM   7015  C CG  . ARG C 3 22  ? 151.216 142.395 140.123 1.00 52.06  ? 2   ARG D CG  1 
ATOM   7016  C CD  . ARG C 3 22  ? 150.451 143.188 139.079 1.00 51.33  ? 2   ARG D CD  1 
ATOM   7017  N NE  . ARG C 3 22  ? 151.159 143.236 137.805 1.00 48.78  ? 2   ARG D NE  1 
ATOM   7018  C CZ  . ARG C 3 22  ? 150.846 144.048 136.805 1.00 48.11  ? 2   ARG D CZ  1 
ATOM   7019  N NH1 . ARG C 3 22  ? 149.847 144.909 136.900 1.00 54.12  ? 2   ARG D NH1 1 
ATOM   7020  N NH2 . ARG C 3 22  ? 151.552 143.992 135.680 1.00 45.57  ? 2   ARG D NH2 1 
ATOM   7021  N N   . VAL C 3 23  ? 151.920 137.654 140.640 1.00 51.31  ? 3   VAL D N   1 
ATOM   7022  C CA  . VAL C 3 23  ? 152.189 136.307 140.149 1.00 47.32  ? 3   VAL D CA  1 
ATOM   7023  C C   . VAL C 3 23  ? 150.875 135.721 139.654 1.00 47.50  ? 3   VAL D C   1 
ATOM   7024  O O   . VAL C 3 23  ? 149.918 135.584 140.426 1.00 49.89  ? 3   VAL D O   1 
ATOM   7025  C CB  . VAL C 3 23  ? 152.815 135.416 141.230 1.00 47.92  ? 3   VAL D CB  1 
ATOM   7026  C CG1 . VAL C 3 23  ? 153.549 134.252 140.595 1.00 45.69  ? 3   VAL D CG1 1 
ATOM   7027  C CG2 . VAL C 3 23  ? 153.756 136.226 142.106 1.00 50.22  ? 3   VAL D CG2 1 
ATOM   7028  N N   . GLY C 3 24  ? 150.827 135.371 138.372 1.00 49.35  ? 4   GLY D N   1 
ATOM   7029  C CA  . GLY C 3 24  ? 149.649 134.782 137.785 1.00 51.46  ? 4   GLY D CA  1 
ATOM   7030  C C   . GLY C 3 24  ? 149.864 134.394 136.337 1.00 49.30  ? 4   GLY D C   1 
ATOM   7031  O O   . GLY C 3 24  ? 150.895 134.705 135.734 1.00 44.96  ? 4   GLY D O   1 
ATOM   7032  N N   . PRO C 3 25  ? 148.889 133.694 135.749 1.00 50.96  ? 5   PRO D N   1 
ATOM   7033  C CA  . PRO C 3 25  ? 149.000 133.341 134.327 1.00 46.89  ? 5   PRO D CA  1 
ATOM   7034  C C   . PRO C 3 25  ? 148.812 134.519 133.389 1.00 49.73  ? 5   PRO D C   1 
ATOM   7035  O O   . PRO C 3 25  ? 149.333 134.482 132.267 1.00 46.48  ? 5   PRO D O   1 
ATOM   7036  C CB  . PRO C 3 25  ? 147.888 132.302 134.138 1.00 48.16  ? 5   PRO D CB  1 
ATOM   7037  C CG  . PRO C 3 25  ? 146.868 132.677 135.158 1.00 52.35  ? 5   PRO D CG  1 
ATOM   7038  C CD  . PRO C 3 25  ? 147.632 133.209 136.345 1.00 52.28  ? 5   PRO D CD  1 
ATOM   7039  N N   . GLN C 3 26  ? 148.090 135.555 133.809 1.00 50.93  ? 6   GLN D N   1 
ATOM   7040  C CA  . GLN C 3 26  ? 147.891 136.752 133.006 1.00 43.29  ? 6   GLN D CA  1 
ATOM   7041  C C   . GLN C 3 26  ? 148.979 137.793 133.225 1.00 41.01  ? 6   GLN D C   1 
ATOM   7042  O O   . GLN C 3 26  ? 148.935 138.860 132.604 1.00 43.06  ? 6   GLN D O   1 
ATOM   7043  C CB  . GLN C 3 26  ? 146.510 137.355 133.298 1.00 42.77  ? 6   GLN D CB  1 
ATOM   7044  C CG  . GLN C 3 26  ? 146.477 138.370 134.428 1.00 48.94  ? 6   GLN D CG  1 
ATOM   7045  C CD  . GLN C 3 26  ? 145.924 137.791 135.713 1.00 55.97  ? 6   GLN D CD  1 
ATOM   7046  O OE1 . GLN C 3 26  ? 146.058 136.598 135.979 1.00 56.02  ? 6   GLN D OE1 1 
ATOM   7047  N NE2 . GLN C 3 26  ? 145.297 138.638 136.520 1.00 56.02  ? 6   GLN D NE2 1 
ATOM   7048  N N   . TYR C 3 27  ? 149.956 137.504 134.079 1.00 42.49  ? 7   TYR D N   1 
ATOM   7049  C CA  . TYR C 3 27  ? 151.093 138.382 134.323 1.00 43.30  ? 7   TYR D CA  1 
ATOM   7050  C C   . TYR C 3 27  ? 152.399 137.835 133.772 1.00 38.90  ? 7   TYR D C   1 
ATOM   7051  O O   . TYR C 3 27  ? 153.208 138.600 133.246 1.00 37.06  ? 7   TYR D O   1 
ATOM   7052  C CB  . TYR C 3 27  ? 151.249 138.631 135.827 1.00 44.22  ? 7   TYR D CB  1 
ATOM   7053  C CG  . TYR C 3 27  ? 150.050 139.290 136.465 1.00 49.07  ? 7   TYR D CG  1 
ATOM   7054  C CD1 . TYR C 3 27  ? 149.517 140.458 135.942 1.00 49.05  ? 7   TYR D CD1 1 
ATOM   7055  C CD2 . TYR C 3 27  ? 149.456 138.749 137.595 1.00 50.66  ? 7   TYR D CD2 1 
ATOM   7056  C CE1 . TYR C 3 27  ? 148.423 141.066 136.523 1.00 50.65  ? 7   TYR D CE1 1 
ATOM   7057  C CE2 . TYR C 3 27  ? 148.361 139.348 138.181 1.00 51.98  ? 7   TYR D CE2 1 
ATOM   7058  C CZ  . TYR C 3 27  ? 147.849 140.506 137.642 1.00 54.51  ? 7   TYR D CZ  1 
ATOM   7059  O OH  . TYR C 3 27  ? 146.758 141.108 138.225 1.00 58.52  ? 7   TYR D OH  1 
ATOM   7060  N N   . GLN C 3 28  ? 152.621 136.529 133.876 1.00 38.21  ? 8   GLN D N   1 
ATOM   7061  C CA  . GLN C 3 28  ? 153.853 135.920 133.407 1.00 33.47  ? 8   GLN D CA  1 
ATOM   7062  C C   . GLN C 3 28  ? 153.745 135.550 131.930 1.00 34.25  ? 8   GLN D C   1 
ATOM   7063  O O   . GLN C 3 28  ? 152.665 135.542 131.335 1.00 35.30  ? 8   GLN D O   1 
ATOM   7064  C CB  . GLN C 3 28  ? 154.188 134.684 134.239 1.00 32.52  ? 8   GLN D CB  1 
ATOM   7065  C CG  . GLN C 3 28  ? 155.177 134.938 135.359 1.00 30.57  ? 8   GLN D CG  1 
ATOM   7066  C CD  . GLN C 3 28  ? 154.565 135.714 136.504 1.00 35.92  ? 8   GLN D CD  1 
ATOM   7067  O OE1 . GLN C 3 28  ? 153.435 135.451 136.908 1.00 41.52  ? 8   GLN D OE1 1 
ATOM   7068  N NE2 . GLN C 3 28  ? 155.309 136.674 137.035 1.00 32.83  ? 8   GLN D NE2 1 
ATOM   7069  N N   . ALA C 3 29  ? 154.893 135.240 131.339 1.00 34.97  ? 9   ALA D N   1 
ATOM   7070  C CA  . ALA C 3 29  ? 154.985 134.839 129.945 1.00 37.58  ? 9   ALA D CA  1 
ATOM   7071  C C   . ALA C 3 29  ? 155.046 133.321 129.835 1.00 44.93  ? 9   ALA D C   1 
ATOM   7072  O O   . ALA C 3 29  ? 155.559 132.636 130.722 1.00 48.27  ? 9   ALA D O   1 
ATOM   7073  C CB  . ALA C 3 29  ? 156.214 135.459 129.277 1.00 32.21  ? 9   ALA D CB  1 
ATOM   7074  N N   . VAL C 3 30  ? 154.514 132.801 128.732 1.00 46.43  ? 10  VAL D N   1 
ATOM   7075  C CA  . VAL C 3 30  ? 154.490 131.365 128.479 1.00 48.88  ? 10  VAL D CA  1 
ATOM   7076  C C   . VAL C 3 30  ? 155.777 131.023 127.735 1.00 50.77  ? 10  VAL D C   1 
ATOM   7077  O O   . VAL C 3 30  ? 155.876 131.201 126.520 1.00 51.22  ? 10  VAL D O   1 
ATOM   7078  C CB  . VAL C 3 30  ? 153.245 130.949 127.694 1.00 47.34  ? 10  VAL D CB  1 
ATOM   7079  C CG1 . VAL C 3 30  ? 153.333 129.486 127.289 1.00 48.25  ? 10  VAL D CG1 1 
ATOM   7080  C CG2 . VAL C 3 30  ? 151.994 131.203 128.516 1.00 45.78  ? 10  VAL D CG2 1 
ATOM   7081  N N   . VAL C 3 31  ? 156.774 130.545 128.473 1.00 49.48  ? 11  VAL D N   1 
ATOM   7082  C CA  . VAL C 3 31  ? 158.058 130.174 127.886 1.00 52.38  ? 11  VAL D CA  1 
ATOM   7083  C C   . VAL C 3 31  ? 157.875 128.881 127.101 1.00 59.93  ? 11  VAL D C   1 
ATOM   7084  O O   . VAL C 3 31  ? 156.953 128.105 127.392 1.00 59.53  ? 11  VAL D O   1 
ATOM   7085  C CB  . VAL C 3 31  ? 159.150 130.036 128.961 1.00 47.09  ? 11  VAL D CB  1 
ATOM   7086  C CG1 . VAL C 3 31  ? 159.110 131.220 129.910 1.00 45.05  ? 11  VAL D CG1 1 
ATOM   7087  C CG2 . VAL C 3 31  ? 158.993 128.732 129.724 1.00 50.47  ? 11  VAL D CG2 1 
ATOM   7088  N N   . PRO C 3 32  ? 158.707 128.612 126.093 1.00 62.53  ? 12  PRO D N   1 
ATOM   7089  C CA  . PRO C 3 32  ? 158.558 127.365 125.331 1.00 62.27  ? 12  PRO D CA  1 
ATOM   7090  C C   . PRO C 3 32  ? 158.933 126.137 126.143 1.00 65.35  ? 12  PRO D C   1 
ATOM   7091  O O   . PRO C 3 32  ? 159.261 126.236 127.330 1.00 61.99  ? 12  PRO D O   1 
ATOM   7092  C CB  . PRO C 3 32  ? 159.516 127.562 124.147 1.00 62.05  ? 12  PRO D CB  1 
ATOM   7093  C CG  . PRO C 3 32  ? 159.726 129.043 124.060 1.00 55.16  ? 12  PRO D CG  1 
ATOM   7094  C CD  . PRO C 3 32  ? 159.693 129.515 125.477 1.00 52.67  ? 12  PRO D CD  1 
ATOM   7095  N N   . ASP C 3 33  ? 158.876 124.971 125.510 1.00 72.05  ? 13  ASP D N   1 
ATOM   7096  C CA  . ASP C 3 33  ? 159.354 123.730 126.101 1.00 75.33  ? 13  ASP D CA  1 
ATOM   7097  C C   . ASP C 3 33  ? 160.728 123.423 125.527 1.00 74.74  ? 13  ASP D C   1 
ATOM   7098  O O   . ASP C 3 33  ? 160.922 123.480 124.309 1.00 74.21  ? 13  ASP D O   1 
ATOM   7099  C CB  . ASP C 3 33  ? 158.387 122.578 125.821 1.00 75.68  ? 13  ASP D CB  1 
ATOM   7100  C CG  . ASP C 3 33  ? 157.361 122.397 126.922 1.00 77.35  ? 13  ASP D CG  1 
ATOM   7101  O OD1 . ASP C 3 33  ? 157.742 121.951 128.025 1.00 73.05  ? 13  ASP D OD1 1 
ATOM   7102  O OD2 . ASP C 3 33  ? 156.173 122.703 126.686 1.00 76.43  ? 13  ASP D OD2 1 
ATOM   7103  N N   . PHE C 3 34  ? 161.681 123.114 126.403 1.00 73.01  ? 14  PHE D N   1 
ATOM   7104  C CA  . PHE C 3 34  ? 163.048 122.898 125.953 1.00 74.52  ? 14  PHE D CA  1 
ATOM   7105  C C   . PHE C 3 34  ? 163.140 121.641 125.098 1.00 83.95  ? 14  PHE D C   1 
ATOM   7106  O O   . PHE C 3 34  ? 162.712 120.558 125.509 1.00 84.54  ? 14  PHE D O   1 
ATOM   7107  C CB  . PHE C 3 34  ? 163.994 122.800 127.147 1.00 67.17  ? 14  PHE D CB  1 
ATOM   7108  C CG  . PHE C 3 34  ? 165.439 122.697 126.759 1.00 70.26  ? 14  PHE D CG  1 
ATOM   7109  C CD1 . PHE C 3 34  ? 165.985 123.583 125.847 1.00 64.00  ? 14  PHE D CD1 1 
ATOM   7110  C CD2 . PHE C 3 34  ? 166.249 121.713 127.299 1.00 73.86  ? 14  PHE D CD2 1 
ATOM   7111  C CE1 . PHE C 3 34  ? 167.311 123.493 125.483 1.00 64.83  ? 14  PHE D CE1 1 
ATOM   7112  C CE2 . PHE C 3 34  ? 167.579 121.619 126.938 1.00 73.47  ? 14  PHE D CE2 1 
ATOM   7113  C CZ  . PHE C 3 34  ? 168.110 122.510 126.027 1.00 71.39  ? 14  PHE D CZ  1 
ATOM   7114  N N   . ASP C 3 35  ? 163.708 121.792 123.903 1.00 84.87  ? 15  ASP D N   1 
ATOM   7115  C CA  . ASP C 3 35  ? 163.863 120.703 122.941 1.00 86.56  ? 15  ASP D CA  1 
ATOM   7116  C C   . ASP C 3 35  ? 165.331 120.640 122.546 1.00 86.53  ? 15  ASP D C   1 
ATOM   7117  O O   . ASP C 3 35  ? 165.763 121.330 121.612 1.00 87.37  ? 15  ASP D O   1 
ATOM   7118  C CB  . ASP C 3 35  ? 162.968 120.912 121.721 1.00 92.48  ? 15  ASP D CB  1 
ATOM   7119  C CG  . ASP C 3 35  ? 161.492 120.923 122.073 1.00 93.52  ? 15  ASP D CG  1 
ATOM   7120  O OD1 . ASP C 3 35  ? 161.120 120.333 123.110 1.00 90.97  ? 15  ASP D OD1 1 
ATOM   7121  O OD2 . ASP C 3 35  ? 160.704 121.523 121.313 1.00 95.86  ? 15  ASP D OD2 1 
ATOM   7122  N N   . PRO C 3 36  ? 166.133 119.832 123.246 1.00 85.96  ? 16  PRO D N   1 
ATOM   7123  C CA  . PRO C 3 36  ? 167.581 119.803 122.963 1.00 89.05  ? 16  PRO D CA  1 
ATOM   7124  C C   . PRO C 3 36  ? 167.924 119.453 121.525 1.00 92.50  ? 16  PRO D C   1 
ATOM   7125  O O   . PRO C 3 36  ? 168.882 120.006 120.970 1.00 88.59  ? 16  PRO D O   1 
ATOM   7126  C CB  . PRO C 3 36  ? 168.103 118.740 123.940 1.00 86.56  ? 16  PRO D CB  1 
ATOM   7127  C CG  . PRO C 3 36  ? 167.094 118.691 125.034 1.00 81.67  ? 16  PRO D CG  1 
ATOM   7128  C CD  . PRO C 3 36  ? 165.770 118.988 124.397 1.00 82.09  ? 16  PRO D CD  1 
ATOM   7129  N N   . ALA C 3 37  ? 167.170 118.544 120.904 1.00 95.84  ? 17  ALA D N   1 
ATOM   7130  C CA  . ALA C 3 37  ? 167.446 118.181 119.518 1.00 97.60  ? 17  ALA D CA  1 
ATOM   7131  C C   . ALA C 3 37  ? 167.066 119.306 118.564 1.00 98.61  ? 17  ALA D C   1 
ATOM   7132  O O   . ALA C 3 37  ? 167.722 119.503 117.535 1.00 99.59  ? 17  ALA D O   1 
ATOM   7133  C CB  . ALA C 3 37  ? 166.706 116.894 119.156 1.00 97.80  ? 17  ALA D CB  1 
ATOM   7134  N N   . LYS C 3 38  ? 166.012 120.054 118.889 1.00 98.83  ? 18  LYS D N   1 
ATOM   7135  C CA  . LYS C 3 38  ? 165.505 121.093 118.002 1.00 101.43 ? 18  LYS D CA  1 
ATOM   7136  C C   . LYS C 3 38  ? 166.282 122.399 118.101 1.00 97.34  ? 18  LYS D C   1 
ATOM   7137  O O   . LYS C 3 38  ? 165.984 123.332 117.348 1.00 92.57  ? 18  LYS D O   1 
ATOM   7138  C CB  . LYS C 3 38  ? 164.021 121.360 118.288 1.00 97.21  ? 18  LYS D CB  1 
ATOM   7139  C CG  . LYS C 3 38  ? 163.057 120.294 117.764 1.00 98.72  ? 18  LYS D CG  1 
ATOM   7140  C CD  . LYS C 3 38  ? 163.062 119.034 118.617 1.00 99.33  ? 18  LYS D CD  1 
ATOM   7141  C CE  . LYS C 3 38  ? 161.782 118.234 118.435 1.00 103.90 ? 18  LYS D CE  1 
ATOM   7142  N NZ  . LYS C 3 38  ? 161.501 117.366 119.612 1.00 101.21 ? 18  LYS D NZ  1 
ATOM   7143  N N   . LEU C 3 39  ? 167.256 122.496 119.010 1.00 93.63  ? 19  LEU D N   1 
ATOM   7144  C CA  . LEU C 3 39  ? 168.052 123.714 119.119 1.00 85.83  ? 19  LEU D CA  1 
ATOM   7145  C C   . LEU C 3 39  ? 168.828 123.981 117.835 1.00 91.81  ? 19  LEU D C   1 
ATOM   7146  O O   . LEU C 3 39  ? 168.580 124.970 117.137 1.00 85.24  ? 19  LEU D O   1 
ATOM   7147  C CB  . LEU C 3 39  ? 169.004 123.616 120.314 1.00 83.62  ? 19  LEU D CB  1 
ATOM   7148  C CG  . LEU C 3 39  ? 168.400 123.284 121.679 1.00 83.12  ? 19  LEU D CG  1 
ATOM   7149  C CD1 . LEU C 3 39  ? 169.488 123.208 122.739 1.00 76.00  ? 19  LEU D CD1 1 
ATOM   7150  C CD2 . LEU C 3 39  ? 167.344 124.310 122.064 1.00 74.45  ? 19  LEU D CD2 1 
ATOM   7151  N N   . ALA C 3 40  ? 169.763 123.097 117.494 1.00 98.07  ? 20  ALA D N   1 
ATOM   7152  C CA  . ALA C 3 40  ? 170.607 123.286 116.313 1.00 101.81 ? 20  ALA D CA  1 
ATOM   7153  C C   . ALA C 3 40  ? 170.028 122.539 115.110 1.00 104.86 ? 20  ALA D C   1 
ATOM   7154  O O   . ALA C 3 40  ? 170.679 121.709 114.475 1.00 106.30 ? 20  ALA D O   1 
ATOM   7155  C CB  . ALA C 3 40  ? 172.035 122.842 116.609 1.00 101.17 ? 20  ALA D CB  1 
ATOM   7156  N N   . ARG C 3 41  ? 168.771 122.853 114.805 1.00 104.03 ? 21  ARG D N   1 
ATOM   7157  C CA  . ARG C 3 41  ? 168.059 122.226 113.699 1.00 105.43 ? 21  ARG D CA  1 
ATOM   7158  C C   . ARG C 3 41  ? 167.588 123.223 112.653 1.00 104.35 ? 21  ARG D C   1 
ATOM   7159  O O   . ARG C 3 41  ? 167.782 122.994 111.453 1.00 102.12 ? 21  ARG D O   1 
ATOM   7160  C CB  . ARG C 3 41  ? 166.858 121.429 114.234 1.00 104.86 ? 21  ARG D CB  1 
ATOM   7161  C CG  . ARG C 3 41  ? 166.076 120.686 113.162 1.00 107.52 ? 21  ARG D CG  1 
ATOM   7162  C CD  . ARG C 3 41  ? 165.281 119.530 113.753 1.00 109.72 ? 21  ARG D CD  1 
ATOM   7163  N NE  . ARG C 3 41  ? 166.064 118.754 114.708 1.00 109.27 ? 21  ARG D NE  1 
ATOM   7164  C CZ  . ARG C 3 41  ? 166.935 117.812 114.372 1.00 111.36 ? 21  ARG D CZ  1 
ATOM   7165  N NH1 . ARG C 3 41  ? 167.159 117.497 113.107 1.00 112.57 ? 21  ARG D NH1 1 
ATOM   7166  N NH2 . ARG C 3 41  ? 167.596 117.169 115.330 1.00 108.79 ? 21  ARG D NH2 1 
ATOM   7167  N N   . ARG C 3 42  ? 166.973 124.329 113.073 1.00 100.72 ? 22  ARG D N   1 
ATOM   7168  C CA  . ARG C 3 42  ? 166.234 125.208 112.177 1.00 99.08  ? 22  ARG D CA  1 
ATOM   7169  C C   . ARG C 3 42  ? 166.952 126.525 111.898 1.00 96.27  ? 22  ARG D C   1 
ATOM   7170  O O   . ARG C 3 42  ? 166.331 127.457 111.377 1.00 96.69  ? 22  ARG D O   1 
ATOM   7171  C CB  . ARG C 3 42  ? 164.846 125.486 112.754 1.00 92.98  ? 22  ARG D CB  1 
ATOM   7172  C CG  . ARG C 3 42  ? 164.722 125.149 114.231 1.00 90.15  ? 22  ARG D CG  1 
ATOM   7173  C CD  . ARG C 3 42  ? 163.434 125.695 114.823 1.00 86.06  ? 22  ARG D CD  1 
ATOM   7174  N NE  . ARG C 3 42  ? 163.254 125.286 116.211 1.00 81.04  ? 22  ARG D NE  1 
ATOM   7175  C CZ  . ARG C 3 42  ? 162.313 125.761 117.014 1.00 71.22  ? 22  ARG D CZ  1 
ATOM   7176  N NH1 . ARG C 3 42  ? 161.445 126.670 116.600 1.00 70.62  ? 22  ARG D NH1 1 
ATOM   7177  N NH2 . ARG C 3 42  ? 162.241 125.314 118.264 1.00 63.45  ? 22  ARG D NH2 1 
ATOM   7178  N N   . SER C 3 43  ? 168.236 126.627 112.225 1.00 96.30  ? 23  SER D N   1 
ATOM   7179  C CA  . SER C 3 43  ? 168.944 127.900 112.083 1.00 90.36  ? 23  SER D CA  1 
ATOM   7180  C C   . SER C 3 43  ? 169.555 128.062 110.693 1.00 94.34  ? 23  SER D C   1 
ATOM   7181  O O   . SER C 3 43  ? 170.717 128.437 110.540 1.00 88.07  ? 23  SER D O   1 
ATOM   7182  C CB  . SER C 3 43  ? 170.013 128.013 113.162 1.00 75.57  ? 23  SER D CB  1 
ATOM   7183  O OG  . SER C 3 43  ? 171.210 127.367 112.766 1.00 76.83  ? 23  SER D OG  1 
ATOM   7184  N N   . GLN C 3 44  ? 168.761 127.775 109.659 1.00 100.24 ? 24  GLN D N   1 
ATOM   7185  C CA  . GLN C 3 44  ? 169.172 128.020 108.284 1.00 101.85 ? 24  GLN D CA  1 
ATOM   7186  C C   . GLN C 3 44  ? 168.035 128.469 107.376 1.00 104.48 ? 24  GLN D C   1 
ATOM   7187  O O   . GLN C 3 44  ? 168.270 128.663 106.179 1.00 104.91 ? 24  GLN D O   1 
ATOM   7188  C CB  . GLN C 3 44  ? 169.824 126.758 107.688 1.00 101.87 ? 24  GLN D CB  1 
ATOM   7189  C CG  . GLN C 3 44  ? 169.744 125.529 108.587 1.00 100.41 ? 24  GLN D CG  1 
ATOM   7190  C CD  . GLN C 3 44  ? 169.640 124.234 107.808 1.00 104.53 ? 24  GLN D CD  1 
ATOM   7191  O OE1 . GLN C 3 44  ? 169.696 124.228 106.578 1.00 103.88 ? 24  GLN D OE1 1 
ATOM   7192  N NE2 . GLN C 3 44  ? 169.478 123.126 108.522 1.00 106.26 ? 24  GLN D NE2 1 
ATOM   7193  N N   . GLU C 3 45  ? 166.824 128.642 107.893 1.00 102.52 ? 25  GLU D N   1 
ATOM   7194  C CA  . GLU C 3 45  ? 165.642 128.798 107.051 1.00 103.82 ? 25  GLU D CA  1 
ATOM   7195  C C   . GLU C 3 45  ? 164.615 129.644 107.799 1.00 104.82 ? 25  GLU D C   1 
ATOM   7196  O O   . GLU C 3 45  ? 164.967 130.415 108.698 1.00 103.00 ? 25  GLU D O   1 
ATOM   7197  C CB  . GLU C 3 45  ? 165.089 127.423 106.634 1.00 105.67 ? 25  GLU D CB  1 
ATOM   7198  C CG  . GLU C 3 45  ? 165.023 126.405 107.759 1.00 104.71 ? 25  GLU D CG  1 
ATOM   7199  C CD  . GLU C 3 45  ? 166.293 125.588 107.874 1.00 104.27 ? 25  GLU D CD  1 
ATOM   7200  O OE1 . GLU C 3 45  ? 166.975 125.406 106.844 1.00 105.04 ? 25  GLU D OE1 1 
ATOM   7201  O OE2 . GLU C 3 45  ? 166.610 125.133 108.992 1.00 100.83 ? 25  GLU D OE2 1 
ATOM   7202  N N   . ARG C 3 46  ? 163.350 129.527 107.379 1.00 106.41 ? 26  ARG D N   1 
ATOM   7203  C CA  . ARG C 3 46  ? 162.179 130.185 107.956 1.00 104.62 ? 26  ARG D CA  1 
ATOM   7204  C C   . ARG C 3 46  ? 162.087 131.636 107.499 1.00 102.86 ? 26  ARG D C   1 
ATOM   7205  O O   . ARG C 3 46  ? 161.396 131.928 106.518 1.00 101.94 ? 26  ARG D O   1 
ATOM   7206  C CB  . ARG C 3 46  ? 162.181 130.082 109.488 1.00 102.29 ? 26  ARG D CB  1 
ATOM   7207  C CG  . ARG C 3 46  ? 161.080 130.868 110.194 1.00 101.38 ? 26  ARG D CG  1 
ATOM   7208  C CD  . ARG C 3 46  ? 161.445 131.116 111.652 1.00 103.44 ? 26  ARG D CD  1 
ATOM   7209  N NE  . ARG C 3 46  ? 160.670 132.200 112.245 1.00 102.70 ? 26  ARG D NE  1 
ATOM   7210  C CZ  . ARG C 3 46  ? 161.086 133.456 112.331 1.00 95.68  ? 26  ARG D CZ  1 
ATOM   7211  N NH1 . ARG C 3 46  ? 162.269 133.826 111.869 1.00 86.68  ? 26  ARG D NH1 1 
ATOM   7212  N NH2 . ARG C 3 46  ? 160.296 134.364 112.898 1.00 90.37  ? 26  ARG D NH2 1 
ATOM   7213  N N   . ASP C 3 47  ? 162.775 132.551 108.179 1.00 100.87 ? 27  ASP D N   1 
ATOM   7214  C CA  . ASP C 3 47  ? 162.658 133.968 107.841 1.00 100.06 ? 27  ASP D CA  1 
ATOM   7215  C C   . ASP C 3 47  ? 163.830 134.725 108.440 1.00 92.43  ? 27  ASP D C   1 
ATOM   7216  O O   . ASP C 3 47  ? 163.977 134.766 109.666 1.00 87.51  ? 27  ASP D O   1 
ATOM   7217  C CB  . ASP C 3 47  ? 161.334 134.542 108.350 1.00 99.18  ? 27  ASP D CB  1 
ATOM   7218  C CG  . ASP C 3 47  ? 160.296 134.674 107.253 1.00 100.85 ? 27  ASP D CG  1 
ATOM   7219  O OD1 . ASP C 3 47  ? 160.688 134.833 106.078 1.00 96.84  ? 27  ASP D OD1 1 
ATOM   7220  O OD2 . ASP C 3 47  ? 159.088 134.616 107.565 1.00 102.29 ? 27  ASP D OD2 1 
ATOM   7221  N N   . ASN C 3 48  ? 164.659 135.320 107.587 1.00 92.07  ? 28  ASN D N   1 
ATOM   7222  C CA  . ASN C 3 48  ? 165.691 136.247 108.031 1.00 85.30  ? 28  ASN D CA  1 
ATOM   7223  C C   . ASN C 3 48  ? 165.120 137.658 107.975 1.00 76.45  ? 28  ASN D C   1 
ATOM   7224  O O   . ASN C 3 48  ? 164.727 138.132 106.903 1.00 76.69  ? 28  ASN D O   1 
ATOM   7225  C CB  . ASN C 3 48  ? 166.946 136.131 107.167 1.00 87.18  ? 28  ASN D CB  1 
ATOM   7226  C CG  . ASN C 3 48  ? 168.206 136.531 107.914 1.00 88.00  ? 28  ASN D CG  1 
ATOM   7227  O OD1 . ASN C 3 48  ? 168.208 136.641 109.141 1.00 77.36  ? 28  ASN D OD1 1 
ATOM   7228  N ND2 . ASN C 3 48  ? 169.287 136.752 107.175 1.00 85.22  ? 28  ASN D ND2 1 
ATOM   7229  N N   . LEU C 3 49  ? 165.076 138.323 109.124 1.00 69.79  ? 29  LEU D N   1 
ATOM   7230  C CA  . LEU C 3 49  ? 164.396 139.602 109.260 1.00 63.42  ? 29  LEU D CA  1 
ATOM   7231  C C   . LEU C 3 49  ? 165.391 140.749 109.143 1.00 60.98  ? 29  LEU D C   1 
ATOM   7232  O O   . LEU C 3 49  ? 166.538 140.641 109.587 1.00 60.98  ? 29  LEU D O   1 
ATOM   7233  C CB  . LEU C 3 49  ? 163.656 139.674 110.597 1.00 54.31  ? 29  LEU D CB  1 
ATOM   7234  C CG  . LEU C 3 49  ? 162.797 138.445 110.911 1.00 57.55  ? 29  LEU D CG  1 
ATOM   7235  C CD1 . LEU C 3 49  ? 162.475 138.363 112.395 1.00 45.70  ? 29  LEU D CD1 1 
ATOM   7236  C CD2 . LEU C 3 49  ? 161.524 138.452 110.080 1.00 59.38  ? 29  LEU D CD2 1 
ATOM   7237  N N   . GLY C 3 50  ? 164.946 141.840 108.544 1.00 49.57  ? 30  GLY D N   1 
ATOM   7238  C CA  . GLY C 3 50  ? 165.798 142.983 108.296 1.00 42.90  ? 30  GLY D CA  1 
ATOM   7239  C C   . GLY C 3 50  ? 166.385 142.959 106.898 1.00 44.32  ? 30  GLY D C   1 
ATOM   7240  O O   . GLY C 3 50  ? 166.591 141.901 106.295 1.00 51.44  ? 30  GLY D O   1 
ATOM   7241  N N   . MET C 3 51  ? 166.659 144.147 106.368 1.00 40.16  ? 31  MET D N   1 
ATOM   7242  C CA  . MET C 3 51  ? 167.216 144.305 105.030 1.00 39.70  ? 31  MET D CA  1 
ATOM   7243  C C   . MET C 3 51  ? 168.644 144.816 105.154 1.00 38.48  ? 31  MET D C   1 
ATOM   7244  O O   . MET C 3 51  ? 168.887 145.831 105.815 1.00 37.13  ? 31  MET D O   1 
ATOM   7245  C CB  . MET C 3 51  ? 166.365 145.260 104.192 1.00 39.59  ? 31  MET D CB  1 
ATOM   7246  C CG  . MET C 3 51  ? 167.156 146.138 103.234 1.00 48.82  ? 31  MET D CG  1 
ATOM   7247  S SD  . MET C 3 51  ? 166.158 147.440 102.488 1.00 85.42  ? 31  MET D SD  1 
ATOM   7248  C CE  . MET C 3 51  ? 167.417 148.380 101.629 1.00 67.07  ? 31  MET D CE  1 
ATOM   7249  N N   . LEU C 3 52  ? 169.583 144.108 104.532 1.00 37.57  ? 32  LEU D N   1 
ATOM   7250  C CA  . LEU C 3 52  ? 170.979 144.518 104.576 1.00 36.38  ? 32  LEU D CA  1 
ATOM   7251  C C   . LEU C 3 52  ? 171.173 145.802 103.779 1.00 40.64  ? 32  LEU D C   1 
ATOM   7252  O O   . LEU C 3 52  ? 170.725 145.908 102.634 1.00 44.16  ? 32  LEU D O   1 
ATOM   7253  C CB  . LEU C 3 52  ? 171.874 143.409 104.029 1.00 34.38  ? 32  LEU D CB  1 
ATOM   7254  C CG  . LEU C 3 52  ? 173.369 143.516 104.327 1.00 34.53  ? 32  LEU D CG  1 
ATOM   7255  C CD1 . LEU C 3 52  ? 173.606 143.724 105.807 1.00 31.88  ? 32  LEU D CD1 1 
ATOM   7256  C CD2 . LEU C 3 52  ? 174.096 142.277 103.842 1.00 34.77  ? 32  LEU D CD2 1 
ATOM   7257  N N   . VAL C 3 53  ? 171.845 146.777 104.388 1.00 38.31  ? 33  VAL D N   1 
ATOM   7258  C CA  . VAL C 3 53  ? 172.042 148.084 103.773 1.00 36.18  ? 33  VAL D CA  1 
ATOM   7259  C C   . VAL C 3 53  ? 173.525 148.293 103.503 1.00 40.10  ? 33  VAL D C   1 
ATOM   7260  O O   . VAL C 3 53  ? 173.905 148.970 102.542 1.00 49.59  ? 33  VAL D O   1 
ATOM   7261  C CB  . VAL C 3 53  ? 171.473 149.203 104.665 1.00 33.79  ? 33  VAL D CB  1 
ATOM   7262  C CG1 . VAL C 3 53  ? 171.613 150.554 103.990 1.00 40.60  ? 33  VAL D CG1 1 
ATOM   7263  C CG2 . VAL C 3 53  ? 170.020 148.925 105.000 1.00 34.08  ? 33  VAL D CG2 1 
ATOM   7264  N N   . TRP C 3 54  ? 174.373 147.697 104.337 1.00 38.60  ? 34  TRP D N   1 
ATOM   7265  C CA  . TRP C 3 54  ? 175.813 147.846 104.198 1.00 39.42  ? 34  TRP D CA  1 
ATOM   7266  C C   . TRP C 3 54  ? 176.493 146.659 104.862 1.00 37.51  ? 34  TRP D C   1 
ATOM   7267  O O   . TRP C 3 54  ? 176.015 146.139 105.873 1.00 35.68  ? 34  TRP D O   1 
ATOM   7268  C CB  . TRP C 3 54  ? 176.297 149.166 104.812 1.00 36.26  ? 34  TRP D CB  1 
ATOM   7269  C CG  . TRP C 3 54  ? 177.784 149.266 104.966 1.00 39.77  ? 34  TRP D CG  1 
ATOM   7270  C CD1 . TRP C 3 54  ? 178.496 149.176 106.125 1.00 38.31  ? 34  TRP D CD1 1 
ATOM   7271  C CD2 . TRP C 3 54  ? 178.742 149.476 103.922 1.00 42.44  ? 34  TRP D CD2 1 
ATOM   7272  N NE1 . TRP C 3 54  ? 179.837 149.316 105.869 1.00 39.01  ? 34  TRP D NE1 1 
ATOM   7273  C CE2 . TRP C 3 54  ? 180.014 149.501 104.523 1.00 42.53  ? 34  TRP D CE2 1 
ATOM   7274  C CE3 . TRP C 3 54  ? 178.647 149.642 102.538 1.00 47.43  ? 34  TRP D CE3 1 
ATOM   7275  C CZ2 . TRP C 3 54  ? 181.181 149.686 103.790 1.00 46.94  ? 34  TRP D CZ2 1 
ATOM   7276  C CZ3 . TRP C 3 54  ? 179.804 149.827 101.813 1.00 54.07  ? 34  TRP D CZ3 1 
ATOM   7277  C CH2 . TRP C 3 54  ? 181.055 149.848 102.439 1.00 52.99  ? 34  TRP D CH2 1 
ATOM   7278  N N   . SER C 3 55  ? 177.611 146.231 104.275 1.00 41.34  ? 35  SER D N   1 
ATOM   7279  C CA  . SER C 3 55  ? 178.385 145.121 104.791 1.00 42.79  ? 35  SER D CA  1 
ATOM   7280  C C   . SER C 3 55  ? 179.859 145.420 104.560 1.00 47.68  ? 35  SER D C   1 
ATOM   7281  O O   . SER C 3 55  ? 180.227 145.825 103.446 1.00 51.03  ? 35  SER D O   1 
ATOM   7282  C CB  . SER C 3 55  ? 178.007 143.800 104.122 1.00 46.23  ? 35  SER D CB  1 
ATOM   7283  O OG  . SER C 3 55  ? 178.164 142.711 105.013 1.00 47.11  ? 35  SER D OG  1 
ATOM   7284  N N   . PRO C 3 56  ? 180.711 145.244 105.568 1.00 46.62  ? 36  PRO D N   1 
ATOM   7285  C CA  . PRO C 3 56  ? 182.137 145.532 105.385 1.00 53.50  ? 36  PRO D CA  1 
ATOM   7286  C C   . PRO C 3 56  ? 182.778 144.585 104.381 1.00 63.46  ? 36  PRO D C   1 
ATOM   7287  O O   . PRO C 3 56  ? 182.366 143.433 104.227 1.00 62.81  ? 36  PRO D O   1 
ATOM   7288  C CB  . PRO C 3 56  ? 182.723 145.332 106.789 1.00 51.49  ? 36  PRO D CB  1 
ATOM   7289  C CG  . PRO C 3 56  ? 181.550 145.417 107.712 1.00 43.04  ? 36  PRO D CG  1 
ATOM   7290  C CD  . PRO C 3 56  ? 180.409 144.837 106.948 1.00 41.53  ? 36  PRO D CD  1 
ATOM   7291  N N   . ASN C 3 57  ? 183.801 145.087 103.693 1.00 69.39  ? 37  ASN D N   1 
ATOM   7292  C CA  . ASN C 3 57  ? 184.600 144.283 102.776 1.00 78.14  ? 37  ASN D CA  1 
ATOM   7293  C C   . ASN C 3 57  ? 186.068 144.473 103.121 1.00 84.35  ? 37  ASN D C   1 
ATOM   7294  O O   . ASN C 3 57  ? 186.547 145.609 103.199 1.00 86.54  ? 37  ASN D O   1 
ATOM   7295  C CB  . ASN C 3 57  ? 184.330 144.663 101.318 1.00 76.93  ? 37  ASN D CB  1 
ATOM   7296  C CG  . ASN C 3 57  ? 184.326 143.459 100.398 1.00 80.75  ? 37  ASN D CG  1 
ATOM   7297  O OD1 . ASN C 3 57  ? 184.838 142.397 100.746 1.00 82.02  ? 37  ASN D OD1 1 
ATOM   7298  N ND2 . ASN C 3 57  ? 183.744 143.619 99.216  1.00 85.27  ? 37  ASN D ND2 1 
ATOM   7299  N N   . GLN C 3 58  ? 186.779 143.363 103.327 1.00 86.04  ? 38  GLN D N   1 
ATOM   7300  C CA  . GLN C 3 58  ? 188.169 143.445 103.762 1.00 93.10  ? 38  GLN D CA  1 
ATOM   7301  C C   . GLN C 3 58  ? 189.095 143.832 102.615 1.00 96.84  ? 38  GLN D C   1 
ATOM   7302  O O   . GLN C 3 58  ? 190.091 144.534 102.826 1.00 96.81  ? 38  GLN D O   1 
ATOM   7303  C CB  . GLN C 3 58  ? 188.604 142.117 104.381 1.00 95.00  ? 38  GLN D CB  1 
ATOM   7304  C CG  . GLN C 3 58  ? 187.665 141.600 105.461 1.00 98.13  ? 38  GLN D CG  1 
ATOM   7305  C CD  . GLN C 3 58  ? 187.373 142.639 106.528 1.00 99.22  ? 38  GLN D CD  1 
ATOM   7306  O OE1 . GLN C 3 58  ? 188.283 143.284 107.050 1.00 97.37  ? 38  GLN D OE1 1 
ATOM   7307  N NE2 . GLN C 3 58  ? 186.097 142.804 106.860 1.00 90.34  ? 38  GLN D NE2 1 
ATOM   7308  N N   . ASN C 3 59  ? 188.792 143.378 101.395 1.00 96.38  ? 39  ASN D N   1 
ATOM   7309  C CA  . ASN C 3 59  ? 189.660 143.686 100.262 1.00 93.30  ? 39  ASN D CA  1 
ATOM   7310  C C   . ASN C 3 59  ? 189.628 145.168 99.913  1.00 95.23  ? 39  ASN D C   1 
ATOM   7311  O O   . ASN C 3 59  ? 190.564 145.677 99.286  1.00 97.09  ? 39  ASN D O   1 
ATOM   7312  C CB  . ASN C 3 59  ? 189.266 142.839 99.050  1.00 92.42  ? 39  ASN D CB  1 
ATOM   7313  C CG  . ASN C 3 59  ? 187.896 143.194 98.505  1.00 89.78  ? 39  ASN D CG  1 
ATOM   7314  O OD1 . ASN C 3 59  ? 187.089 143.831 99.182  1.00 90.41  ? 39  ASN D OD1 1 
ATOM   7315  N ND2 . ASN C 3 59  ? 187.626 142.779 97.273  1.00 87.38  ? 39  ASN D ND2 1 
ATOM   7316  N N   . LEU C 3 60  ? 188.565 145.869 100.298 1.00 96.44  ? 40  LEU D N   1 
ATOM   7317  C CA  . LEU C 3 60  ? 188.479 147.301 100.048 1.00 98.22  ? 40  LEU D CA  1 
ATOM   7318  C C   . LEU C 3 60  ? 189.538 148.043 100.852 1.00 103.27 ? 40  LEU D C   1 
ATOM   7319  O O   . LEU C 3 60  ? 189.775 147.735 102.024 1.00 105.83 ? 40  LEU D O   1 
ATOM   7320  C CB  . LEU C 3 60  ? 187.084 147.815 100.406 1.00 95.57  ? 40  LEU D CB  1 
ATOM   7321  C CG  . LEU C 3 60  ? 186.469 148.857 99.471  1.00 97.76  ? 40  LEU D CG  1 
ATOM   7322  C CD1 . LEU C 3 60  ? 186.923 148.623 98.040  1.00 98.12  ? 40  LEU D CD1 1 
ATOM   7323  C CD2 . LEU C 3 60  ? 184.953 148.838 99.567  1.00 90.76  ? 40  LEU D CD2 1 
ATOM   7324  N N   . SER C 3 61  ? 190.176 149.023 100.220 1.00 103.71 ? 41  SER D N   1 
ATOM   7325  C CA  . SER C 3 61  ? 191.199 149.818 100.879 1.00 106.93 ? 41  SER D CA  1 
ATOM   7326  C C   . SER C 3 61  ? 190.576 151.031 101.560 1.00 108.47 ? 41  SER D C   1 
ATOM   7327  O O   . SER C 3 61  ? 189.552 151.559 101.118 1.00 106.43 ? 41  SER D O   1 
ATOM   7328  C CB  . SER C 3 61  ? 192.265 150.269 99.880  1.00 109.35 ? 41  SER D CB  1 
ATOM   7329  O OG  . SER C 3 61  ? 192.039 151.602 99.457  1.00 109.90 ? 41  SER D OG  1 
ATOM   7330  N N   . GLU C 3 62  ? 191.207 151.463 102.654 1.00 107.98 ? 42  GLU D N   1 
ATOM   7331  C CA  . GLU C 3 62  ? 190.708 152.615 103.398 1.00 109.50 ? 42  GLU D CA  1 
ATOM   7332  C C   . GLU C 3 62  ? 190.792 153.889 102.565 1.00 110.48 ? 42  GLU D C   1 
ATOM   7333  O O   . GLU C 3 62  ? 189.846 154.688 102.531 1.00 109.73 ? 42  GLU D O   1 
ATOM   7334  C CB  . GLU C 3 62  ? 191.496 152.769 104.699 1.00 111.18 ? 42  GLU D CB  1 
ATOM   7335  C CG  . GLU C 3 62  ? 190.946 151.965 105.865 1.00 112.02 ? 42  GLU D CG  1 
ATOM   7336  C CD  . GLU C 3 62  ? 189.861 152.700 106.622 1.00 109.64 ? 42  GLU D CD  1 
ATOM   7337  O OE1 . GLU C 3 62  ? 190.045 153.899 106.916 1.00 108.27 ? 42  GLU D OE1 1 
ATOM   7338  O OE2 . GLU C 3 62  ? 188.820 152.078 106.924 1.00 105.79 ? 42  GLU D OE2 1 
ATOM   7339  N N   . ALA C 3 63  ? 191.924 154.094 101.885 1.00 110.72 ? 43  ALA D N   1 
ATOM   7340  C CA  . ALA C 3 63  ? 192.110 155.308 101.096 1.00 110.21 ? 43  ALA D CA  1 
ATOM   7341  C C   . ALA C 3 63  ? 191.110 155.385 99.951  1.00 109.29 ? 43  ALA D C   1 
ATOM   7342  O O   . ALA C 3 63  ? 190.574 156.460 99.657  1.00 107.43 ? 43  ALA D O   1 
ATOM   7343  C CB  . ALA C 3 63  ? 193.542 155.374 100.566 1.00 108.88 ? 43  ALA D CB  1 
ATOM   7344  N N   . LYS C 3 64  ? 190.853 154.256 99.285  1.00 108.49 ? 44  LYS D N   1 
ATOM   7345  C CA  . LYS C 3 64  ? 189.875 154.248 98.202  1.00 109.69 ? 44  LYS D CA  1 
ATOM   7346  C C   . LYS C 3 64  ? 188.482 154.588 98.716  1.00 107.87 ? 44  LYS D C   1 
ATOM   7347  O O   . LYS C 3 64  ? 187.739 155.333 98.068  1.00 106.73 ? 44  LYS D O   1 
ATOM   7348  C CB  . LYS C 3 64  ? 189.873 152.890 97.501  1.00 110.78 ? 44  LYS D CB  1 
ATOM   7349  C CG  . LYS C 3 64  ? 190.781 152.819 96.286  1.00 112.08 ? 44  LYS D CG  1 
ATOM   7350  C CD  . LYS C 3 64  ? 189.999 153.028 95.000  1.00 113.36 ? 44  LYS D CD  1 
ATOM   7351  C CE  . LYS C 3 64  ? 190.522 152.138 93.885  1.00 115.70 ? 44  LYS D CE  1 
ATOM   7352  N NZ  . LYS C 3 64  ? 191.773 152.676 93.282  1.00 117.29 ? 44  LYS D NZ  1 
ATOM   7353  N N   . LEU C 3 65  ? 188.112 154.050 99.881  1.00 107.10 ? 45  LEU D N   1 
ATOM   7354  C CA  . LEU C 3 65  ? 186.812 154.368 100.464 1.00 103.32 ? 45  LEU D CA  1 
ATOM   7355  C C   . LEU C 3 65  ? 186.705 155.847 100.811 1.00 104.47 ? 45  LEU D C   1 
ATOM   7356  O O   . LEU C 3 65  ? 185.678 156.483 100.540 1.00 103.70 ? 45  LEU D O   1 
ATOM   7357  C CB  . LEU C 3 65  ? 186.570 153.506 101.702 1.00 99.59  ? 45  LEU D CB  1 
ATOM   7358  C CG  . LEU C 3 65  ? 185.399 152.529 101.616 1.00 93.81  ? 45  LEU D CG  1 
ATOM   7359  C CD1 . LEU C 3 65  ? 184.998 152.052 102.995 1.00 83.63  ? 45  LEU D CD1 1 
ATOM   7360  C CD2 . LEU C 3 65  ? 184.228 153.204 100.935 1.00 91.68  ? 45  LEU D CD2 1 
ATOM   7361  N N   . ASP C 3 66  ? 187.756 156.415 101.407 1.00 107.43 ? 46  ASP D N   1 
ATOM   7362  C CA  . ASP C 3 66  ? 187.730 157.837 101.739 1.00 108.18 ? 46  ASP D CA  1 
ATOM   7363  C C   . ASP C 3 66  ? 187.627 158.695 100.484 1.00 108.18 ? 46  ASP D C   1 
ATOM   7364  O O   . ASP C 3 66  ? 186.864 159.669 100.448 1.00 107.34 ? 46  ASP D O   1 
ATOM   7365  C CB  . ASP C 3 66  ? 188.972 158.210 102.548 1.00 107.05 ? 46  ASP D CB  1 
ATOM   7366  C CG  . ASP C 3 66  ? 189.103 157.398 103.822 1.00 107.59 ? 46  ASP D CG  1 
ATOM   7367  O OD1 . ASP C 3 66  ? 188.070 157.147 104.476 1.00 108.00 ? 46  ASP D OD1 1 
ATOM   7368  O OD2 . ASP C 3 66  ? 190.239 157.012 104.170 1.00 106.63 ? 46  ASP D OD2 1 
ATOM   7369  N N   . GLU C 3 67  ? 188.384 158.344 99.441  1.00 107.84 ? 47  GLU D N   1 
ATOM   7370  C CA  . GLU C 3 67  ? 188.330 159.102 98.195  1.00 107.19 ? 47  GLU D CA  1 
ATOM   7371  C C   . GLU C 3 67  ? 186.954 159.006 97.549  1.00 106.14 ? 47  GLU D C   1 
ATOM   7372  O O   . GLU C 3 67  ? 186.428 160.005 97.042  1.00 105.35 ? 47  GLU D O   1 
ATOM   7373  C CB  . GLU C 3 67  ? 189.416 158.608 97.238  1.00 109.14 ? 47  GLU D CB  1 
ATOM   7374  C CG  . GLU C 3 67  ? 189.254 159.084 95.803  1.00 111.36 ? 47  GLU D CG  1 
ATOM   7375  C CD  . GLU C 3 67  ? 188.895 157.960 94.853  1.00 114.34 ? 47  GLU D CD  1 
ATOM   7376  O OE1 . GLU C 3 67  ? 189.629 156.949 94.822  1.00 113.73 ? 47  GLU D OE1 1 
ATOM   7377  O OE2 . GLU C 3 67  ? 187.880 158.085 94.136  1.00 114.02 ? 47  GLU D OE2 1 
ATOM   7378  N N   . TYR C 3 68  ? 186.356 157.813 97.556  1.00 105.19 ? 48  TYR D N   1 
ATOM   7379  C CA  . TYR C 3 68  ? 185.020 157.654 96.993  1.00 103.15 ? 48  TYR D CA  1 
ATOM   7380  C C   . TYR C 3 68  ? 183.999 158.472 97.770  1.00 101.88 ? 48  TYR D C   1 
ATOM   7381  O O   . TYR C 3 68  ? 183.118 159.101 97.174  1.00 101.07 ? 48  TYR D O   1 
ATOM   7382  C CB  . TYR C 3 68  ? 184.626 156.177 96.972  1.00 100.87 ? 48  TYR D CB  1 
ATOM   7383  C CG  . TYR C 3 68  ? 183.149 155.944 96.738  1.00 95.54  ? 48  TYR D CG  1 
ATOM   7384  C CD1 . TYR C 3 68  ? 182.607 156.036 95.465  1.00 96.29  ? 48  TYR D CD1 1 
ATOM   7385  C CD2 . TYR C 3 68  ? 182.300 155.626 97.789  1.00 91.83  ? 48  TYR D CD2 1 
ATOM   7386  C CE1 . TYR C 3 68  ? 181.260 155.824 95.247  1.00 97.03  ? 48  TYR D CE1 1 
ATOM   7387  C CE2 . TYR C 3 68  ? 180.953 155.413 97.580  1.00 88.63  ? 48  TYR D CE2 1 
ATOM   7388  C CZ  . TYR C 3 68  ? 180.439 155.513 96.307  1.00 91.11  ? 48  TYR D CZ  1 
ATOM   7389  O OH  . TYR C 3 68  ? 179.097 155.301 96.094  1.00 90.90  ? 48  TYR D OH  1 
ATOM   7390  N N   . ILE C 3 69  ? 184.102 158.481 99.102  1.00 101.00 ? 49  ILE D N   1 
ATOM   7391  C CA  . ILE C 3 69  ? 183.184 159.281 99.909  1.00 99.70  ? 49  ILE D CA  1 
ATOM   7392  C C   . ILE C 3 69  ? 183.346 160.761 99.583  1.00 102.11 ? 49  ILE D C   1 
ATOM   7393  O O   . ILE C 3 69  ? 182.357 161.488 99.421  1.00 103.63 ? 49  ILE D O   1 
ATOM   7394  C CB  . ILE C 3 69  ? 183.395 158.997 101.410 1.00 98.93  ? 49  ILE D CB  1 
ATOM   7395  C CG1 . ILE C 3 69  ? 182.370 157.982 101.928 1.00 91.80  ? 49  ILE D CG1 1 
ATOM   7396  C CG2 . ILE C 3 69  ? 183.296 160.275 102.231 1.00 100.96 ? 49  ILE D CG2 1 
ATOM   7397  C CD1 . ILE C 3 69  ? 182.296 156.699 101.137 1.00 89.31  ? 49  ILE D CD1 1 
ATOM   7398  N N   . ALA C 3 70  ? 184.593 161.224 99.457  1.00 104.13 ? 50  ALA D N   1 
ATOM   7399  C CA  . ALA C 3 70  ? 184.835 162.636 99.169  1.00 104.36 ? 50  ALA D CA  1 
ATOM   7400  C C   . ALA C 3 70  ? 184.293 163.030 97.800  1.00 105.39 ? 50  ALA D C   1 
ATOM   7401  O O   . ALA C 3 70  ? 183.696 164.103 97.645  1.00 104.97 ? 50  ALA D O   1 
ATOM   7402  C CB  . ALA C 3 70  ? 186.329 162.940 99.262  1.00 102.59 ? 50  ALA D CB  1 
ATOM   7403  N N   . ILE C 3 71  ? 184.498 162.180 96.791  1.00 106.38 ? 51  ILE D N   1 
ATOM   7404  C CA  . ILE C 3 71  ? 184.021 162.504 95.449  1.00 107.22 ? 51  ILE D CA  1 
ATOM   7405  C C   . ILE C 3 71  ? 182.499 162.449 95.390  1.00 106.55 ? 51  ILE D C   1 
ATOM   7406  O O   . ILE C 3 71  ? 181.861 163.295 94.752  1.00 107.50 ? 51  ILE D O   1 
ATOM   7407  C CB  . ILE C 3 71  ? 184.666 161.574 94.405  1.00 109.12 ? 51  ILE D CB  1 
ATOM   7408  C CG1 . ILE C 3 71  ? 186.190 161.715 94.440  1.00 108.10 ? 51  ILE D CG1 1 
ATOM   7409  C CG2 . ILE C 3 71  ? 184.134 161.884 93.014  1.00 108.70 ? 51  ILE D CG2 1 
ATOM   7410  C CD1 . ILE C 3 71  ? 186.892 161.105 93.246  1.00 111.67 ? 51  ILE D CD1 1 
ATOM   7411  N N   . ALA C 3 72  ? 181.889 161.464 96.054  1.00 105.65 ? 52  ALA D N   1 
ATOM   7412  C CA  . ALA C 3 72  ? 180.433 161.399 96.094  1.00 104.54 ? 52  ALA D CA  1 
ATOM   7413  C C   . ALA C 3 72  ? 179.852 162.616 96.800  1.00 106.49 ? 52  ALA D C   1 
ATOM   7414  O O   . ALA C 3 72  ? 178.787 163.115 96.418  1.00 105.29 ? 52  ALA D O   1 
ATOM   7415  C CB  . ALA C 3 72  ? 179.981 160.111 96.779  1.00 96.93  ? 52  ALA D CB  1 
ATOM   7416  N N   . LYS C 3 73  ? 180.537 163.111 97.833  1.00 108.42 ? 53  LYS D N   1 
ATOM   7417  C CA  . LYS C 3 73  ? 180.076 164.318 98.508  1.00 107.21 ? 53  LYS D CA  1 
ATOM   7418  C C   . LYS C 3 73  ? 180.188 165.530 97.592  1.00 108.27 ? 53  LYS D C   1 
ATOM   7419  O O   . LYS C 3 73  ? 179.184 166.175 97.270  1.00 108.12 ? 53  LYS D O   1 
ATOM   7420  C CB  . LYS C 3 73  ? 180.866 164.540 99.798  1.00 107.61 ? 53  LYS D CB  1 
ATOM   7421  C CG  . LYS C 3 73  ? 180.120 165.374 100.825 1.00 107.41 ? 53  LYS D CG  1 
ATOM   7422  C CD  . LYS C 3 73  ? 181.045 165.879 101.917 1.00 107.93 ? 53  LYS D CD  1 
ATOM   7423  C CE  . LYS C 3 73  ? 180.361 166.941 102.760 1.00 106.97 ? 53  LYS D CE  1 
ATOM   7424  N NZ  . LYS C 3 73  ? 179.266 167.616 102.011 1.00 110.03 ? 53  LYS D NZ  1 
ATOM   7425  N N   . GLU C 3 74  ? 181.403 165.856 97.157  1.00 109.16 ? 54  GLU D N   1 
ATOM   7426  C CA  . GLU C 3 74  ? 181.587 167.021 96.292  1.00 111.13 ? 54  GLU D CA  1 
ATOM   7427  C C   . GLU C 3 74  ? 181.526 166.648 94.813  1.00 109.13 ? 54  GLU D C   1 
ATOM   7428  O O   . GLU C 3 74  ? 182.361 167.066 94.011  1.00 108.10 ? 54  GLU D O   1 
ATOM   7429  C CB  . GLU C 3 74  ? 182.906 167.708 96.625  1.00 110.73 ? 54  GLU D CB  1 
ATOM   7430  C CG  . GLU C 3 74  ? 182.804 168.770 97.707  1.00 111.44 ? 54  GLU D CG  1 
ATOM   7431  C CD  . GLU C 3 74  ? 182.669 168.178 99.096  1.00 116.12 ? 54  GLU D CD  1 
ATOM   7432  O OE1 . GLU C 3 74  ? 183.686 167.705 99.644  1.00 116.99 ? 54  GLU D OE1 1 
ATOM   7433  O OE2 . GLU C 3 74  ? 181.545 168.189 99.640  1.00 117.33 ? 54  GLU D OE2 1 
ATOM   7434  N N   . LYS C 3 75  ? 180.533 165.855 94.442  1.00 110.01 ? 55  LYS D N   1 
ATOM   7435  C CA  . LYS C 3 75  ? 180.148 165.697 93.044  1.00 111.95 ? 55  LYS D CA  1 
ATOM   7436  C C   . LYS C 3 75  ? 178.647 165.818 92.830  1.00 111.53 ? 55  LYS D C   1 
ATOM   7437  O O   . LYS C 3 75  ? 178.219 166.406 91.834  1.00 110.83 ? 55  LYS D O   1 
ATOM   7438  C CB  . LYS C 3 75  ? 180.648 164.346 92.506  1.00 111.70 ? 55  LYS D CB  1 
ATOM   7439  C CG  . LYS C 3 75  ? 180.955 164.348 91.016  1.00 111.17 ? 55  LYS D CG  1 
ATOM   7440  C CD  . LYS C 3 75  ? 181.971 165.420 90.652  1.00 111.30 ? 55  LYS D CD  1 
ATOM   7441  C CE  . LYS C 3 75  ? 183.309 165.175 91.332  1.00 112.05 ? 55  LYS D CE  1 
ATOM   7442  N NZ  . LYS C 3 75  ? 184.353 166.122 90.856  1.00 110.60 ? 55  LYS D NZ  1 
ATOM   7443  N N   . HIS C 3 76  ? 177.834 165.273 93.743  1.00 111.89 ? 56  HIS D N   1 
ATOM   7444  C CA  . HIS C 3 76  ? 176.384 165.362 93.630  1.00 114.37 ? 56  HIS D CA  1 
ATOM   7445  C C   . HIS C 3 76  ? 175.705 165.600 94.974  1.00 110.91 ? 56  HIS D C   1 
ATOM   7446  O O   . HIS C 3 76  ? 174.480 165.447 95.065  1.00 107.70 ? 56  HIS D O   1 
ATOM   7447  C CB  . HIS C 3 76  ? 175.797 164.094 92.988  1.00 114.52 ? 56  HIS D CB  1 
ATOM   7448  C CG  . HIS C 3 76  ? 176.700 163.439 91.991  1.00 114.45 ? 56  HIS D CG  1 
ATOM   7449  N ND1 . HIS C 3 76  ? 177.699 162.562 92.354  1.00 114.12 ? 56  HIS D ND1 1 
ATOM   7450  C CD2 . HIS C 3 76  ? 176.752 163.530 90.641  1.00 114.33 ? 56  HIS D CD2 1 
ATOM   7451  C CE1 . HIS C 3 76  ? 178.328 162.141 91.271  1.00 114.68 ? 56  HIS D CE1 1 
ATOM   7452  N NE2 . HIS C 3 76  ? 177.774 162.715 90.219  1.00 115.33 ? 56  HIS D NE2 1 
ATOM   7453  N N   . GLY C 3 77  ? 176.448 165.970 96.014  1.00 108.19 ? 57  GLY D N   1 
ATOM   7454  C CA  . GLY C 3 77  ? 175.870 166.147 97.331  1.00 106.25 ? 57  GLY D CA  1 
ATOM   7455  C C   . GLY C 3 77  ? 175.376 164.861 97.963  1.00 105.07 ? 57  GLY D C   1 
ATOM   7456  O O   . GLY C 3 77  ? 174.281 164.821 98.532  1.00 104.98 ? 57  GLY D O   1 
ATOM   7457  N N   . TYR C 3 78  ? 176.173 163.801 97.865  1.00 103.58 ? 58  TYR D N   1 
ATOM   7458  C CA  . TYR C 3 78  ? 175.875 162.534 98.519  1.00 98.42  ? 58  TYR D CA  1 
ATOM   7459  C C   . TYR C 3 78  ? 176.515 162.527 99.902  1.00 96.93  ? 58  TYR D C   1 
ATOM   7460  O O   . TYR C 3 78  ? 177.725 162.739 100.029 1.00 98.19  ? 58  TYR D O   1 
ATOM   7461  C CB  . TYR C 3 78  ? 176.398 161.358 97.695  1.00 100.01 ? 58  TYR D CB  1 
ATOM   7462  C CG  . TYR C 3 78  ? 175.457 160.855 96.625  1.00 103.73 ? 58  TYR D CG  1 
ATOM   7463  C CD1 . TYR C 3 78  ? 175.242 161.583 95.464  1.00 107.30 ? 58  TYR D CD1 1 
ATOM   7464  C CD2 . TYR C 3 78  ? 174.798 159.642 96.770  1.00 99.90  ? 58  TYR D CD2 1 
ATOM   7465  C CE1 . TYR C 3 78  ? 174.389 161.121 94.481  1.00 111.60 ? 58  TYR D CE1 1 
ATOM   7466  C CE2 . TYR C 3 78  ? 173.944 159.173 95.795  1.00 106.03 ? 58  TYR D CE2 1 
ATOM   7467  C CZ  . TYR C 3 78  ? 173.744 159.914 94.651  1.00 114.87 ? 58  TYR D CZ  1 
ATOM   7468  O OH  . TYR C 3 78  ? 172.891 159.449 93.676  1.00 120.44 ? 58  TYR D OH  1 
ATOM   7469  N N   . ASN C 3 79  ? 175.712 162.279 100.933 1.00 91.19  ? 59  ASN D N   1 
ATOM   7470  C CA  . ASN C 3 79  ? 176.259 162.140 102.272 1.00 84.29  ? 59  ASN D CA  1 
ATOM   7471  C C   . ASN C 3 79  ? 176.941 160.780 102.411 1.00 81.84  ? 59  ASN D C   1 
ATOM   7472  O O   . ASN C 3 79  ? 176.970 159.971 101.481 1.00 84.13  ? 59  ASN D O   1 
ATOM   7473  C CB  . ASN C 3 79  ? 175.167 162.333 103.321 1.00 81.46  ? 59  ASN D CB  1 
ATOM   7474  C CG  . ASN C 3 79  ? 173.854 161.707 102.917 1.00 85.33  ? 59  ASN D CG  1 
ATOM   7475  O OD1 . ASN C 3 79  ? 173.562 161.568 101.731 1.00 91.74  ? 59  ASN D OD1 1 
ATOM   7476  N ND2 . ASN C 3 79  ? 173.049 161.327 103.901 1.00 82.89  ? 59  ASN D ND2 1 
ATOM   7477  N N   . MET C 3 80  ? 177.509 160.528 103.592 1.00 76.52  ? 60  MET D N   1 
ATOM   7478  C CA  . MET C 3 80  ? 178.225 159.275 103.811 1.00 71.99  ? 60  MET D CA  1 
ATOM   7479  C C   . MET C 3 80  ? 177.295 158.074 103.692 1.00 70.73  ? 60  MET D C   1 
ATOM   7480  O O   . MET C 3 80  ? 177.654 157.063 103.079 1.00 69.51  ? 60  MET D O   1 
ATOM   7481  C CB  . MET C 3 80  ? 178.903 159.293 105.180 1.00 71.45  ? 60  MET D CB  1 
ATOM   7482  C CG  . MET C 3 80  ? 180.080 158.343 105.303 1.00 70.94  ? 60  MET D CG  1 
ATOM   7483  S SD  . MET C 3 80  ? 181.211 158.782 106.638 1.00 86.64  ? 60  MET D SD  1 
ATOM   7484  C CE  . MET C 3 80  ? 180.661 160.439 107.036 1.00 59.40  ? 60  MET D CE  1 
ATOM   7485  N N   . GLU C 3 81  ? 176.095 158.169 104.267 1.00 70.79  ? 61  GLU D N   1 
ATOM   7486  C CA  . GLU C 3 81  ? 175.175 157.036 104.264 1.00 62.85  ? 61  GLU D CA  1 
ATOM   7487  C C   . GLU C 3 81  ? 174.725 156.680 102.852 1.00 70.32  ? 61  GLU D C   1 
ATOM   7488  O O   . GLU C 3 81  ? 174.703 155.501 102.480 1.00 71.25  ? 61  GLU D O   1 
ATOM   7489  C CB  . GLU C 3 81  ? 173.970 157.346 105.151 1.00 55.83  ? 61  GLU D CB  1 
ATOM   7490  C CG  . GLU C 3 81  ? 173.381 156.141 105.855 1.00 49.48  ? 61  GLU D CG  1 
ATOM   7491  C CD  . GLU C 3 81  ? 172.052 156.451 106.514 1.00 48.09  ? 61  GLU D CD  1 
ATOM   7492  O OE1 . GLU C 3 81  ? 171.765 157.644 106.738 1.00 48.75  ? 61  GLU D OE1 1 
ATOM   7493  O OE2 . GLU C 3 81  ? 171.293 155.503 106.806 1.00 42.78  ? 61  GLU D OE2 1 
ATOM   7494  N N   . GLN C 3 82  ? 174.367 157.685 102.048 1.00 74.79  ? 62  GLN D N   1 
ATOM   7495  C CA  . GLN C 3 82  ? 173.896 157.420 100.692 1.00 76.28  ? 62  GLN D CA  1 
ATOM   7496  C C   . GLN C 3 82  ? 175.008 156.854 99.815  1.00 76.79  ? 62  GLN D C   1 
ATOM   7497  O O   . GLN C 3 82  ? 174.781 155.911 99.047  1.00 79.60  ? 62  GLN D O   1 
ATOM   7498  C CB  . GLN C 3 82  ? 173.324 158.697 100.080 1.00 82.98  ? 62  GLN D CB  1 
ATOM   7499  C CG  . GLN C 3 82  ? 171.897 158.997 100.505 1.00 83.93  ? 62  GLN D CG  1 
ATOM   7500  C CD  . GLN C 3 82  ? 171.398 160.326 99.975  1.00 95.73  ? 62  GLN D CD  1 
ATOM   7501  O OE1 . GLN C 3 82  ? 172.153 161.092 99.377  1.00 96.67  ? 62  GLN D OE1 1 
ATOM   7502  N NE2 . GLN C 3 82  ? 170.120 160.608 100.196 1.00 99.00  ? 62  GLN D NE2 1 
ATOM   7503  N N   . ALA C 3 83  ? 176.215 157.415 99.914  1.00 75.48  ? 63  ALA D N   1 
ATOM   7504  C CA  . ALA C 3 83  ? 177.336 156.896 99.137  1.00 77.43  ? 63  ALA D CA  1 
ATOM   7505  C C   . ALA C 3 83  ? 177.685 155.474 99.556  1.00 76.10  ? 63  ALA D C   1 
ATOM   7506  O O   . ALA C 3 83  ? 178.002 154.628 98.711  1.00 78.28  ? 63  ALA D O   1 
ATOM   7507  C CB  . ALA C 3 83  ? 178.549 157.813 99.290  1.00 82.70  ? 63  ALA D CB  1 
ATOM   7508  N N   . LEU C 3 84  ? 177.640 155.195 100.860 1.00 74.60  ? 64  LEU D N   1 
ATOM   7509  C CA  . LEU C 3 84  ? 177.915 153.846 101.343 1.00 66.63  ? 64  LEU D CA  1 
ATOM   7510  C C   . LEU C 3 84  ? 176.867 152.860 100.848 1.00 69.10  ? 64  LEU D C   1 
ATOM   7511  O O   . LEU C 3 84  ? 177.195 151.727 100.480 1.00 71.78  ? 64  LEU D O   1 
ATOM   7512  C CB  . LEU C 3 84  ? 177.975 153.846 102.868 1.00 60.38  ? 64  LEU D CB  1 
ATOM   7513  C CG  . LEU C 3 84  ? 179.290 154.308 103.492 1.00 54.39  ? 64  LEU D CG  1 
ATOM   7514  C CD1 . LEU C 3 84  ? 179.321 153.926 104.950 1.00 45.32  ? 64  LEU D CD1 1 
ATOM   7515  C CD2 . LEU C 3 84  ? 180.480 153.720 102.754 1.00 56.05  ? 64  LEU D CD2 1 
ATOM   7516  N N   . GLY C 3 85  ? 175.598 153.268 100.843 1.00 70.83  ? 65  GLY D N   1 
ATOM   7517  C CA  . GLY C 3 85  ? 174.561 152.407 100.302 1.00 72.13  ? 65  GLY D CA  1 
ATOM   7518  C C   . GLY C 3 85  ? 174.731 152.157 98.817  1.00 76.16  ? 65  GLY D C   1 
ATOM   7519  O O   . GLY C 3 85  ? 174.496 151.048 98.332  1.00 78.94  ? 65  GLY D O   1 
ATOM   7520  N N   . MET C 3 86  ? 175.137 153.188 98.072  1.00 80.65  ? 66  MET D N   1 
ATOM   7521  C CA  . MET C 3 86  ? 175.381 153.020 96.643  1.00 84.17  ? 66  MET D CA  1 
ATOM   7522  C C   . MET C 3 86  ? 176.546 152.071 96.386  1.00 84.28  ? 66  MET D C   1 
ATOM   7523  O O   . MET C 3 86  ? 176.491 151.247 95.466  1.00 87.17  ? 66  MET D O   1 
ATOM   7524  C CB  . MET C 3 86  ? 175.640 154.377 95.989  1.00 88.36  ? 66  MET D CB  1 
ATOM   7525  C CG  . MET C 3 86  ? 175.617 154.349 94.467  1.00 96.75  ? 66  MET D CG  1 
ATOM   7526  S SD  . MET C 3 86  ? 173.980 154.561 93.733  1.00 115.27 ? 66  MET D SD  1 
ATOM   7527  C CE  . MET C 3 86  ? 173.046 155.242 95.103  1.00 103.31 ? 66  MET D CE  1 
ATOM   7528  N N   . LEU C 3 87  ? 177.614 152.179 97.180  1.00 81.77  ? 67  LEU D N   1 
ATOM   7529  C CA  . LEU C 3 87  ? 178.758 151.289 96.998  1.00 80.69  ? 67  LEU D CA  1 
ATOM   7530  C C   . LEU C 3 87  ? 178.384 149.839 97.279  1.00 81.39  ? 67  LEU D C   1 
ATOM   7531  O O   . LEU C 3 87  ? 178.828 148.928 96.571  1.00 80.24  ? 67  LEU D O   1 
ATOM   7532  C CB  . LEU C 3 87  ? 179.917 151.722 97.893  1.00 78.78  ? 67  LEU D CB  1 
ATOM   7533  C CG  . LEU C 3 87  ? 181.255 151.047 97.589  1.00 79.21  ? 67  LEU D CG  1 
ATOM   7534  C CD1 . LEU C 3 87  ? 181.486 150.950 96.090  1.00 88.29  ? 67  LEU D CD1 1 
ATOM   7535  C CD2 . LEU C 3 87  ? 182.389 151.791 98.256  1.00 77.77  ? 67  LEU D CD2 1 
ATOM   7536  N N   . PHE C 3 88  ? 177.579 149.604 98.318  1.00 79.90  ? 68  PHE D N   1 
ATOM   7537  C CA  . PHE C 3 88  ? 177.093 148.255 98.583  1.00 73.50  ? 68  PHE D CA  1 
ATOM   7538  C C   . PHE C 3 88  ? 176.225 147.743 97.443  1.00 79.22  ? 68  PHE D C   1 
ATOM   7539  O O   . PHE C 3 88  ? 176.211 146.539 97.165  1.00 77.31  ? 68  PHE D O   1 
ATOM   7540  C CB  . PHE C 3 88  ? 176.311 148.226 99.896  1.00 61.89  ? 68  PHE D CB  1 
ATOM   7541  C CG  . PHE C 3 88  ? 175.845 146.855 100.295 1.00 59.73  ? 68  PHE D CG  1 
ATOM   7542  C CD1 . PHE C 3 88  ? 176.755 145.844 100.538 1.00 57.18  ? 68  PHE D CD1 1 
ATOM   7543  C CD2 . PHE C 3 88  ? 174.496 146.579 100.425 1.00 53.21  ? 68  PHE D CD2 1 
ATOM   7544  C CE1 . PHE C 3 88  ? 176.331 144.585 100.903 1.00 49.41  ? 68  PHE D CE1 1 
ATOM   7545  C CE2 . PHE C 3 88  ? 174.066 145.321 100.790 1.00 47.82  ? 68  PHE D CE2 1 
ATOM   7546  C CZ  . PHE C 3 88  ? 174.985 144.323 101.029 1.00 47.38  ? 68  PHE D CZ  1 
ATOM   7547  N N   . TRP C 3 89  ? 175.491 148.640 96.780  1.00 82.00  ? 69  TRP D N   1 
ATOM   7548  C CA  . TRP C 3 89  ? 174.622 148.228 95.683  1.00 87.38  ? 69  TRP D CA  1 
ATOM   7549  C C   . TRP C 3 89  ? 175.430 147.650 94.527  1.00 93.53  ? 69  TRP D C   1 
ATOM   7550  O O   . TRP C 3 89  ? 175.053 146.624 93.949  1.00 93.97  ? 69  TRP D O   1 
ATOM   7551  C CB  . TRP C 3 89  ? 173.778 149.420 95.225  1.00 89.92  ? 69  TRP D CB  1 
ATOM   7552  C CG  . TRP C 3 89  ? 172.934 149.186 94.002  1.00 100.42 ? 69  TRP D CG  1 
ATOM   7553  C CD1 . TRP C 3 89  ? 173.363 149.090 92.708  1.00 101.05 ? 69  TRP D CD1 1 
ATOM   7554  C CD2 . TRP C 3 89  ? 171.509 149.044 93.962  1.00 106.29 ? 69  TRP D CD2 1 
ATOM   7555  N NE1 . TRP C 3 89  ? 172.295 148.884 91.869  1.00 104.71 ? 69  TRP D NE1 1 
ATOM   7556  C CE2 . TRP C 3 89  ? 171.145 148.853 92.614  1.00 108.45 ? 69  TRP D CE2 1 
ATOM   7557  C CE3 . TRP C 3 89  ? 170.506 149.054 94.936  1.00 105.28 ? 69  TRP D CE3 1 
ATOM   7558  C CZ2 . TRP C 3 89  ? 169.822 148.674 92.216  1.00 108.19 ? 69  TRP D CZ2 1 
ATOM   7559  C CZ3 . TRP C 3 89  ? 169.193 148.876 94.539  1.00 108.88 ? 69  TRP D CZ3 1 
ATOM   7560  C CH2 . TRP C 3 89  ? 168.863 148.689 93.191  1.00 110.15 ? 69  TRP D CH2 1 
ATOM   7561  N N   . HIS C 3 90  ? 176.540 148.292 94.173  1.00 93.09  ? 70  HIS D N   1 
ATOM   7562  C CA  . HIS C 3 90  ? 177.373 147.831 93.062  1.00 93.37  ? 70  HIS D CA  1 
ATOM   7563  C C   . HIS C 3 90  ? 178.506 146.921 93.532  1.00 93.45  ? 70  HIS D C   1 
ATOM   7564  O O   . HIS C 3 90  ? 179.662 147.096 93.149  1.00 96.73  ? 70  HIS D O   1 
ATOM   7565  C CB  . HIS C 3 90  ? 177.919 149.031 92.298  1.00 94.93  ? 70  HIS D CB  1 
ATOM   7566  C CG  . HIS C 3 90  ? 176.868 149.812 91.573  1.00 99.36  ? 70  HIS D CG  1 
ATOM   7567  N ND1 . HIS C 3 90  ? 176.352 149.416 90.358  1.00 101.22 ? 70  HIS D ND1 1 
ATOM   7568  C CD2 . HIS C 3 90  ? 176.233 150.964 91.895  1.00 102.63 ? 70  HIS D CD2 1 
ATOM   7569  C CE1 . HIS C 3 90  ? 175.446 150.292 89.961  1.00 105.19 ? 70  HIS D CE1 1 
ATOM   7570  N NE2 . HIS C 3 90  ? 175.354 151.240 90.876  1.00 105.59 ? 70  HIS D NE2 1 
ATOM   7571  N N   . LYS C 3 91  ? 178.160 145.929 94.351  1.00 90.88  ? 71  LYS D N   1 
ATOM   7572  C CA  . LYS C 3 91  ? 179.064 144.852 94.771  1.00 90.42  ? 71  LYS D CA  1 
ATOM   7573  C C   . LYS C 3 91  ? 180.437 145.373 95.198  1.00 89.01  ? 71  LYS D C   1 
ATOM   7574  O O   . LYS C 3 91  ? 181.479 144.815 94.847  1.00 90.94  ? 71  LYS D O   1 
ATOM   7575  C CB  . LYS C 3 91  ? 179.198 143.805 93.668  1.00 92.79  ? 71  LYS D CB  1 
ATOM   7576  C CG  . LYS C 3 91  ? 177.882 143.153 93.278  1.00 92.67  ? 71  LYS D CG  1 
ATOM   7577  C CD  . LYS C 3 91  ? 177.379 142.230 94.376  1.00 90.97  ? 71  LYS D CD  1 
ATOM   7578  C CE  . LYS C 3 91  ? 176.267 141.324 93.874  1.00 95.77  ? 71  LYS D CE  1 
ATOM   7579  N NZ  . LYS C 3 91  ? 175.248 142.072 93.085  1.00 98.13  ? 71  LYS D NZ  1 
ATOM   7580  N N   . HIS C 3 92  ? 180.427 146.457 95.974  1.00 84.81  ? 72  HIS D N   1 
ATOM   7581  C CA  . HIS C 3 92  ? 181.639 147.026 96.570  1.00 87.48  ? 72  HIS D CA  1 
ATOM   7582  C C   . HIS C 3 92  ? 182.714 147.317 95.524  1.00 93.09  ? 72  HIS D C   1 
ATOM   7583  O O   . HIS C 3 92  ? 183.904 147.079 95.740  1.00 93.97  ? 72  HIS D O   1 
ATOM   7584  C CB  . HIS C 3 92  ? 182.197 146.111 97.661  1.00 84.41  ? 72  HIS D CB  1 
ATOM   7585  C CG  . HIS C 3 92  ? 181.419 146.137 98.938  1.00 78.72  ? 72  HIS D CG  1 
ATOM   7586  N ND1 . HIS C 3 92  ? 180.503 145.163 99.270  1.00 73.99  ? 72  HIS D ND1 1 
ATOM   7587  C CD2 . HIS C 3 92  ? 181.430 147.012 99.970  1.00 73.27  ? 72  HIS D CD2 1 
ATOM   7588  C CE1 . HIS C 3 92  ? 179.979 145.439 100.451 1.00 65.35  ? 72  HIS D CE1 1 
ATOM   7589  N NE2 . HIS C 3 92  ? 180.523 146.557 100.896 1.00 65.93  ? 72  HIS D NE2 1 
ATOM   7590  N N   . ASN C 3 93  ? 182.292 147.840 94.376  1.00 97.04  ? 73  ASN D N   1 
ATOM   7591  C CA  . ASN C 3 93  ? 183.221 148.223 93.319  1.00 100.14 ? 73  ASN D CA  1 
ATOM   7592  C C   . ASN C 3 93  ? 183.084 149.717 93.072  1.00 102.99 ? 73  ASN D C   1 
ATOM   7593  O O   . ASN C 3 93  ? 182.003 150.195 92.712  1.00 102.18 ? 73  ASN D O   1 
ATOM   7594  C CB  . ASN C 3 93  ? 182.968 147.429 92.036  1.00 99.84  ? 73  ASN D CB  1 
ATOM   7595  C CG  . ASN C 3 93  ? 184.095 147.577 91.033  1.00 104.69 ? 73  ASN D CG  1 
ATOM   7596  O OD1 . ASN C 3 93  ? 183.870 147.603 89.825  1.00 106.50 ? 73  ASN D OD1 1 
ATOM   7597  N ND2 . ASN C 3 93  ? 185.321 147.678 91.534  1.00 104.43 ? 73  ASN D ND2 1 
ATOM   7598  N N   . ILE C 3 94  ? 184.183 150.449 93.266  1.00 104.58 ? 74  ILE D N   1 
ATOM   7599  C CA  . ILE C 3 94  ? 184.142 151.905 93.188  1.00 105.94 ? 74  ILE D CA  1 
ATOM   7600  C C   . ILE C 3 94  ? 183.922 152.365 91.752  1.00 108.31 ? 74  ILE D C   1 
ATOM   7601  O O   . ILE C 3 94  ? 183.232 153.362 91.505  1.00 110.34 ? 74  ILE D O   1 
ATOM   7602  C CB  . ILE C 3 94  ? 185.429 152.502 93.786  1.00 106.08 ? 74  ILE D CB  1 
ATOM   7603  C CG1 . ILE C 3 94  ? 185.638 151.999 95.213  1.00 103.78 ? 74  ILE D CG1 1 
ATOM   7604  C CG2 . ILE C 3 94  ? 185.363 154.013 93.796  1.00 107.74 ? 74  ILE D CG2 1 
ATOM   7605  C CD1 . ILE C 3 94  ? 186.760 151.000 95.339  1.00 105.14 ? 74  ILE D CD1 1 
ATOM   7606  N N   . GLU C 3 95  ? 184.507 151.653 90.784  1.00 107.39 ? 75  GLU D N   1 
ATOM   7607  C CA  . GLU C 3 95  ? 184.461 152.102 89.394  1.00 108.58 ? 75  GLU D CA  1 
ATOM   7608  C C   . GLU C 3 95  ? 183.030 152.185 88.874  1.00 109.65 ? 75  GLU D C   1 
ATOM   7609  O O   . GLU C 3 95  ? 182.660 153.164 88.215  1.00 110.02 ? 75  GLU D O   1 
ATOM   7610  C CB  . GLU C 3 95  ? 185.298 151.171 88.517  1.00 109.75 ? 75  GLU D CB  1 
ATOM   7611  C CG  . GLU C 3 95  ? 186.692 151.694 88.210  1.00 108.64 ? 75  GLU D CG  1 
ATOM   7612  C CD  . GLU C 3 95  ? 187.730 151.227 89.212  1.00 109.70 ? 75  GLU D CD  1 
ATOM   7613  O OE1 . GLU C 3 95  ? 187.391 151.092 90.406  1.00 110.81 ? 75  GLU D OE1 1 
ATOM   7614  O OE2 . GLU C 3 95  ? 188.887 150.995 88.805  1.00 107.58 ? 75  GLU D OE2 1 
ATOM   7615  N N   . LYS C 3 96  ? 182.210 151.174 89.157  1.00 107.71 ? 76  LYS D N   1 
ATOM   7616  C CA  . LYS C 3 96  ? 180.816 151.209 88.732  1.00 108.01 ? 76  LYS D CA  1 
ATOM   7617  C C   . LYS C 3 96  ? 179.955 152.112 89.604  1.00 107.76 ? 76  LYS D C   1 
ATOM   7618  O O   . LYS C 3 96  ? 178.790 152.342 89.265  1.00 109.35 ? 76  LYS D O   1 
ATOM   7619  C CB  . LYS C 3 96  ? 180.223 149.798 88.721  1.00 107.85 ? 76  LYS D CB  1 
ATOM   7620  C CG  . LYS C 3 96  ? 181.247 148.693 88.569  1.00 107.96 ? 76  LYS D CG  1 
ATOM   7621  C CD  . LYS C 3 96  ? 180.579 147.338 88.412  1.00 110.19 ? 76  LYS D CD  1 
ATOM   7622  C CE  . LYS C 3 96  ? 180.625 146.865 86.968  1.00 108.51 ? 76  LYS D CE  1 
ATOM   7623  N NZ  . LYS C 3 96  ? 179.963 145.543 86.792  1.00 102.78 ? 76  LYS D NZ  1 
ATOM   7624  N N   . SER C 3 97  ? 180.493 152.622 90.710  1.00 106.56 ? 77  SER D N   1 
ATOM   7625  C CA  . SER C 3 97  ? 179.755 153.527 91.581  1.00 107.50 ? 77  SER D CA  1 
ATOM   7626  C C   . SER C 3 97  ? 180.014 154.994 91.275  1.00 112.47 ? 77  SER D C   1 
ATOM   7627  O O   . SER C 3 97  ? 179.115 155.820 91.463  1.00 114.97 ? 77  SER D O   1 
ATOM   7628  C CB  . SER C 3 97  ? 180.099 153.249 93.048  1.00 102.72 ? 77  SER D CB  1 
ATOM   7629  O OG  . SER C 3 97  ? 179.303 152.198 93.564  1.00 100.45 ? 77  SER D OG  1 
ATOM   7630  N N   . LEU C 3 98  ? 181.216 155.340 90.810  1.00 111.95 ? 78  LEU D N   1 
ATOM   7631  C CA  . LEU C 3 98  ? 181.497 156.716 90.422  1.00 112.55 ? 78  LEU D CA  1 
ATOM   7632  C C   . LEU C 3 98  ? 180.790 157.118 89.135  1.00 116.45 ? 78  LEU D C   1 
ATOM   7633  O O   . LEU C 3 98  ? 180.672 158.317 88.864  1.00 116.02 ? 78  LEU D O   1 
ATOM   7634  C CB  . LEU C 3 98  ? 183.002 156.929 90.255  1.00 113.35 ? 78  LEU D CB  1 
ATOM   7635  C CG  . LEU C 3 98  ? 183.870 156.948 91.512  1.00 114.76 ? 78  LEU D CG  1 
ATOM   7636  C CD1 . LEU C 3 98  ? 185.260 156.429 91.190  1.00 112.21 ? 78  LEU D CD1 1 
ATOM   7637  C CD2 . LEU C 3 98  ? 183.937 158.345 92.103  1.00 113.99 ? 78  LEU D CD2 1 
ATOM   7638  N N   . ALA C 3 99  ? 180.325 156.152 88.340  1.00 117.37 ? 79  ALA D N   1 
ATOM   7639  C CA  . ALA C 3 99  ? 179.654 156.429 87.076  1.00 116.91 ? 79  ALA D CA  1 
ATOM   7640  C C   . ALA C 3 99  ? 178.166 156.102 87.132  1.00 118.09 ? 79  ALA D C   1 
ATOM   7641  O O   . ALA C 3 99  ? 177.535 155.923 86.086  1.00 119.62 ? 79  ALA D O   1 
ATOM   7642  C CB  . ALA C 3 99  ? 180.324 155.661 85.936  1.00 113.17 ? 79  ALA D CB  1 
ATOM   7643  N N   . ASP C 3 100 ? 177.592 156.018 88.331  1.00 117.30 ? 80  ASP D N   1 
ATOM   7644  C CA  . ASP C 3 100 ? 176.171 155.733 88.487  1.00 120.31 ? 80  ASP D CA  1 
ATOM   7645  C C   . ASP C 3 100 ? 175.430 156.728 89.366  1.00 122.91 ? 80  ASP D C   1 
ATOM   7646  O O   . ASP C 3 100 ? 174.194 156.749 89.325  1.00 123.95 ? 80  ASP D O   1 
ATOM   7647  C CB  . ASP C 3 100 ? 175.964 154.323 89.060  1.00 117.45 ? 80  ASP D CB  1 
ATOM   7648  C CG  . ASP C 3 100 ? 174.730 153.643 88.501  1.00 117.67 ? 80  ASP D CG  1 
ATOM   7649  O OD1 . ASP C 3 100 ? 173.613 153.968 88.955  1.00 119.34 ? 80  ASP D OD1 1 
ATOM   7650  O OD2 . ASP C 3 100 ? 174.876 152.784 87.606  1.00 115.33 ? 80  ASP D OD2 1 
ATOM   7651  N N   . LEU C 3 101 ? 176.129 157.540 90.157  1.00 120.64 ? 81  LEU D N   1 
ATOM   7652  C CA  . LEU C 3 101 ? 175.450 158.531 90.988  1.00 120.05 ? 81  LEU D CA  1 
ATOM   7653  C C   . LEU C 3 101 ? 174.651 159.558 90.189  1.00 122.31 ? 81  LEU D C   1 
ATOM   7654  O O   . LEU C 3 101 ? 173.502 159.832 90.577  1.00 122.26 ? 81  LEU D O   1 
ATOM   7655  C CB  . LEU C 3 101 ? 176.472 159.224 91.899  1.00 117.40 ? 81  LEU D CB  1 
ATOM   7656  C CG  . LEU C 3 101 ? 177.398 158.306 92.699  1.00 113.47 ? 81  LEU D CG  1 
ATOM   7657  C CD1 . LEU C 3 101 ? 178.764 158.947 92.883  1.00 109.84 ? 81  LEU D CD1 1 
ATOM   7658  C CD2 . LEU C 3 101 ? 176.781 157.956 94.042  1.00 108.35 ? 81  LEU D CD2 1 
ATOM   7659  N N   . PRO C 3 102 ? 175.164 160.158 89.107  1.00 125.43 ? 82  PRO D N   1 
ATOM   7660  C CA  . PRO C 3 102 ? 174.361 161.168 88.392  1.00 125.56 ? 82  PRO D CA  1 
ATOM   7661  C C   . PRO C 3 102 ? 173.099 160.617 87.750  1.00 126.56 ? 82  PRO D C   1 
ATOM   7662  O O   . PRO C 3 102 ? 172.216 161.408 87.393  1.00 127.05 ? 82  PRO D O   1 
ATOM   7663  C CB  . PRO C 3 102 ? 175.333 161.709 87.333  1.00 123.96 ? 82  PRO D CB  1 
ATOM   7664  C CG  . PRO C 3 102 ? 176.368 160.656 87.186  1.00 122.55 ? 82  PRO D CG  1 
ATOM   7665  C CD  . PRO C 3 102 ? 176.525 160.066 88.547  1.00 123.06 ? 82  PRO D CD  1 
ATOM   7666  N N   . ASN C 3 103 ? 172.987 159.298 87.579  1.00 125.60 ? 83  ASN D N   1 
ATOM   7667  C CA  . ASN C 3 103 ? 171.805 158.729 86.937  1.00 126.45 ? 83  ASN D CA  1 
ATOM   7668  C C   . ASN C 3 103 ? 170.541 159.039 87.731  1.00 128.86 ? 83  ASN D C   1 
ATOM   7669  O O   . ASN C 3 103 ? 169.505 159.396 87.157  1.00 128.76 ? 83  ASN D O   1 
ATOM   7670  C CB  . ASN C 3 103 ? 171.976 157.220 86.763  1.00 125.74 ? 83  ASN D CB  1 
ATOM   7671  C CG  . ASN C 3 103 ? 173.043 156.869 85.746  1.00 127.99 ? 83  ASN D CG  1 
ATOM   7672  O OD1 . ASN C 3 103 ? 173.923 156.051 86.009  1.00 128.55 ? 83  ASN D OD1 1 
ATOM   7673  N ND2 . ASN C 3 103 ? 172.968 157.487 84.573  1.00 127.64 ? 83  ASN D ND2 1 
ATOM   7674  N N   . PHE C 3 104 ? 170.605 158.908 89.056  1.00 129.27 ? 84  PHE D N   1 
ATOM   7675  C CA  . PHE C 3 104 ? 169.478 159.213 89.938  1.00 129.03 ? 84  PHE D CA  1 
ATOM   7676  C C   . PHE C 3 104 ? 170.025 159.898 91.189  1.00 128.00 ? 84  PHE D C   1 
ATOM   7677  O O   . PHE C 3 104 ? 170.460 159.246 92.141  1.00 124.83 ? 84  PHE D O   1 
ATOM   7678  C CB  . PHE C 3 104 ? 168.660 157.948 90.267  1.00 127.18 ? 84  PHE D CB  1 
ATOM   7679  C CG  . PHE C 3 104 ? 169.473 156.803 90.823  1.00 129.51 ? 84  PHE D CG  1 
ATOM   7680  C CD1 . PHE C 3 104 ? 170.278 156.035 89.996  1.00 127.48 ? 84  PHE D CD1 1 
ATOM   7681  C CD2 . PHE C 3 104 ? 169.410 156.481 92.170  1.00 129.49 ? 84  PHE D CD2 1 
ATOM   7682  C CE1 . PHE C 3 104 ? 171.017 154.985 90.504  1.00 126.50 ? 84  PHE D CE1 1 
ATOM   7683  C CE2 . PHE C 3 104 ? 170.147 155.431 92.683  1.00 127.00 ? 84  PHE D CE2 1 
ATOM   7684  C CZ  . PHE C 3 104 ? 170.951 154.682 91.848  1.00 127.58 ? 84  PHE D CZ  1 
ATOM   7685  N N   . THR C 3 105 ? 170.021 161.225 91.177  1.00 128.75 ? 85  THR D N   1 
ATOM   7686  C CA  . THR C 3 105 ? 170.447 161.984 92.346  1.00 128.95 ? 85  THR D CA  1 
ATOM   7687  C C   . THR C 3 105 ? 169.293 162.101 93.337  1.00 130.61 ? 85  THR D C   1 
ATOM   7688  O O   . THR C 3 105 ? 168.174 162.442 92.937  1.00 130.07 ? 85  THR D O   1 
ATOM   7689  C CB  . THR C 3 105 ? 170.978 163.360 91.937  1.00 129.92 ? 85  THR D CB  1 
ATOM   7690  O OG1 . THR C 3 105 ? 171.472 164.055 93.090  1.00 128.60 ? 85  THR D OG1 1 
ATOM   7691  C CG2 . THR C 3 105 ? 169.923 164.194 91.225  1.00 131.28 ? 85  THR D CG2 1 
ATOM   7692  N N   . PRO C 3 106 ? 169.506 161.790 94.614  1.00 128.40 ? 86  PRO D N   1 
ATOM   7693  C CA  . PRO C 3 106 ? 168.397 161.778 95.576  1.00 128.15 ? 86  PRO D CA  1 
ATOM   7694  C C   . PRO C 3 106 ? 168.012 163.163 96.070  1.00 131.11 ? 86  PRO D C   1 
ATOM   7695  O O   . PRO C 3 106 ? 168.528 163.619 97.096  1.00 128.72 ? 86  PRO D O   1 
ATOM   7696  C CB  . PRO C 3 106 ? 168.940 160.908 96.714  1.00 120.85 ? 86  PRO D CB  1 
ATOM   7697  C CG  . PRO C 3 106 ? 170.414 161.133 96.670  1.00 116.86 ? 86  PRO D CG  1 
ATOM   7698  C CD  . PRO C 3 106 ? 170.778 161.369 95.226  1.00 121.07 ? 86  PRO D CD  1 
ATOM   7699  N N   . PHE C 3 107 ? 167.131 163.846 95.345  1.00 134.24 ? 87  PHE D N   1 
ATOM   7700  C CA  . PHE C 3 107 ? 166.641 165.145 95.788  1.00 134.27 ? 87  PHE D CA  1 
ATOM   7701  C C   . PHE C 3 107 ? 166.043 165.025 97.186  1.00 133.85 ? 87  PHE D C   1 
ATOM   7702  O O   . PHE C 3 107 ? 165.176 164.166 97.410  1.00 131.51 ? 87  PHE D O   1 
ATOM   7703  C CB  . PHE C 3 107 ? 165.589 165.696 94.826  1.00 133.27 ? 87  PHE D CB  1 
ATOM   7704  C CG  . PHE C 3 107 ? 165.961 165.575 93.377  1.00 137.96 ? 87  PHE D CG  1 
ATOM   7705  C CD1 . PHE C 3 107 ? 166.885 166.438 92.813  1.00 140.13 ? 87  PHE D CD1 1 
ATOM   7706  C CD2 . PHE C 3 107 ? 165.378 164.608 92.575  1.00 137.00 ? 87  PHE D CD2 1 
ATOM   7707  C CE1 . PHE C 3 107 ? 167.223 166.337 91.478  1.00 139.80 ? 87  PHE D CE1 1 
ATOM   7708  C CE2 . PHE C 3 107 ? 165.715 164.499 91.240  1.00 138.13 ? 87  PHE D CE2 1 
ATOM   7709  C CZ  . PHE C 3 107 ? 166.639 165.365 90.690  1.00 138.03 ? 87  PHE D CZ  1 
ATOM   7710  N N   . PRO C 3 108 ? 166.467 165.848 98.143  1.00 133.72 ? 88  PRO D N   1 
ATOM   7711  C CA  . PRO C 3 108 ? 165.933 165.736 99.505  1.00 128.87 ? 88  PRO D CA  1 
ATOM   7712  C C   . PRO C 3 108 ? 164.577 166.406 99.642  1.00 127.08 ? 88  PRO D C   1 
ATOM   7713  O O   . PRO C 3 108 ? 163.982 166.822 98.643  1.00 124.75 ? 88  PRO D O   1 
ATOM   7714  C CB  . PRO C 3 108 ? 166.998 166.434 100.357 1.00 127.32 ? 88  PRO D CB  1 
ATOM   7715  C CG  . PRO C 3 108 ? 167.652 167.414 99.428  1.00 129.36 ? 88  PRO D CG  1 
ATOM   7716  C CD  . PRO C 3 108 ? 167.430 166.955 98.007  1.00 132.10 ? 88  PRO D CD  1 
ATOM   7717  N N   . ASP C 3 109 ? 164.074 166.492 100.873 1.00 124.09 ? 89  ASP D N   1 
ATOM   7718  C CA  . ASP C 3 109 ? 162.808 167.166 101.127 1.00 116.71 ? 89  ASP D CA  1 
ATOM   7719  C C   . ASP C 3 109 ? 162.850 168.590 100.591 1.00 114.64 ? 89  ASP D C   1 
ATOM   7720  O O   . ASP C 3 109 ? 163.727 169.379 100.952 1.00 113.22 ? 89  ASP D O   1 
ATOM   7721  C CB  . ASP C 3 109 ? 162.512 167.173 102.628 1.00 110.25 ? 89  ASP D CB  1 
ATOM   7722  C CG  . ASP C 3 109 ? 162.047 165.822 103.137 1.00 103.26 ? 89  ASP D CG  1 
ATOM   7723  O OD1 . ASP C 3 109 ? 162.636 164.798 102.733 1.00 107.63 ? 89  ASP D OD1 1 
ATOM   7724  O OD2 . ASP C 3 109 ? 161.095 165.786 103.945 1.00 94.61  ? 89  ASP D OD2 1 
ATOM   7725  N N   . GLU C 3 110 ? 161.894 168.914 99.724  1.00 113.85 ? 90  GLU D N   1 
ATOM   7726  C CA  . GLU C 3 110 ? 161.844 170.213 99.056  1.00 112.08 ? 90  GLU D CA  1 
ATOM   7727  C C   . GLU C 3 110 ? 161.079 171.177 99.957  1.00 106.60 ? 90  GLU D C   1 
ATOM   7728  O O   . GLU C 3 110 ? 159.863 171.332 99.847  1.00 103.19 ? 90  GLU D O   1 
ATOM   7729  C CB  . GLU C 3 110 ? 161.202 170.092 97.679  1.00 113.12 ? 90  GLU D CB  1 
ATOM   7730  C CG  . GLU C 3 110 ? 160.202 168.955 97.558  1.00 113.61 ? 90  GLU D CG  1 
ATOM   7731  C CD  . GLU C 3 110 ? 159.588 168.864 96.175  1.00 113.33 ? 90  GLU D CD  1 
ATOM   7732  O OE1 . GLU C 3 110 ? 158.664 169.651 95.879  1.00 109.96 ? 90  GLU D OE1 1 
ATOM   7733  O OE2 . GLU C 3 110 ? 160.031 168.007 95.383  1.00 113.06 ? 90  GLU D OE2 1 
ATOM   7734  N N   . TRP C 3 111 ? 161.808 171.828 100.859 1.00 104.53 ? 91  TRP D N   1 
ATOM   7735  C CA  . TRP C 3 111 ? 161.242 172.828 101.758 1.00 101.06 ? 91  TRP D CA  1 
ATOM   7736  C C   . TRP C 3 111 ? 161.541 174.202 101.170 1.00 102.09 ? 91  TRP D C   1 
ATOM   7737  O O   . TRP C 3 111 ? 162.644 174.732 101.330 1.00 99.24  ? 91  TRP D O   1 
ATOM   7738  C CB  . TRP C 3 111 ? 161.808 172.682 103.167 1.00 97.22  ? 91  TRP D CB  1 
ATOM   7739  C CG  . TRP C 3 111 ? 161.023 171.743 104.027 1.00 90.42  ? 91  TRP D CG  1 
ATOM   7740  C CD1 . TRP C 3 111 ? 161.211 170.400 104.156 1.00 91.20  ? 91  TRP D CD1 1 
ATOM   7741  C CD2 . TRP C 3 111 ? 159.911 172.075 104.866 1.00 86.34  ? 91  TRP D CD2 1 
ATOM   7742  N NE1 . TRP C 3 111 ? 160.291 169.875 105.030 1.00 84.31  ? 91  TRP D NE1 1 
ATOM   7743  C CE2 . TRP C 3 111 ? 159.481 170.884 105.480 1.00 81.14  ? 91  TRP D CE2 1 
ATOM   7744  C CE3 . TRP C 3 111 ? 159.240 173.265 105.161 1.00 88.77  ? 91  TRP D CE3 1 
ATOM   7745  C CZ2 . TRP C 3 111 ? 158.411 170.847 106.370 1.00 74.90  ? 91  TRP D CZ2 1 
ATOM   7746  C CZ3 . TRP C 3 111 ? 158.179 173.226 106.045 1.00 85.92  ? 91  TRP D CZ3 1 
ATOM   7747  C CH2 . TRP C 3 111 ? 157.774 172.025 106.638 1.00 80.32  ? 91  TRP D CH2 1 
ATOM   7748  N N   . THR C 3 112 ? 160.557 174.773 100.484 1.00 103.97 ? 92  THR D N   1 
ATOM   7749  C CA  . THR C 3 112 ? 160.711 176.100 99.913  1.00 102.62 ? 92  THR D CA  1 
ATOM   7750  C C   . THR C 3 112 ? 160.742 177.153 101.017 1.00 103.38 ? 92  THR D C   1 
ATOM   7751  O O   . THR C 3 112 ? 160.316 176.917 102.151 1.00 102.58 ? 92  THR D O   1 
ATOM   7752  C CB  . THR C 3 112 ? 159.578 176.400 98.932  1.00 101.31 ? 92  THR D CB  1 
ATOM   7753  O OG1 . THR C 3 112 ? 158.320 176.321 99.615  1.00 102.60 ? 92  THR D OG1 1 
ATOM   7754  C CG2 . THR C 3 112 ? 159.588 175.404 97.782  1.00 99.99  ? 92  THR D CG2 1 
ATOM   7755  N N   . VAL C 3 113 ? 161.266 178.331 100.670 1.00 103.90 ? 93  VAL D N   1 
ATOM   7756  C CA  . VAL C 3 113 ? 161.353 179.420 101.639 1.00 104.28 ? 93  VAL D CA  1 
ATOM   7757  C C   . VAL C 3 113 ? 159.967 179.840 102.105 1.00 101.63 ? 93  VAL D C   1 
ATOM   7758  O O   . VAL C 3 113 ? 159.779 180.202 103.274 1.00 101.54 ? 93  VAL D O   1 
ATOM   7759  C CB  . VAL C 3 113 ? 162.132 180.606 101.041 1.00 107.69 ? 93  VAL D CB  1 
ATOM   7760  C CG1 . VAL C 3 113 ? 162.512 181.591 102.132 1.00 102.69 ? 93  VAL D CG1 1 
ATOM   7761  C CG2 . VAL C 3 113 ? 163.371 180.108 100.315 1.00 107.17 ? 93  VAL D CG2 1 
ATOM   7762  N N   . GLU C 3 114 ? 158.978 179.803 101.209 1.00 100.94 ? 94  GLU D N   1 
ATOM   7763  C CA  . GLU C 3 114 ? 157.608 180.116 101.600 1.00 101.41 ? 94  GLU D CA  1 
ATOM   7764  C C   . GLU C 3 114 ? 157.105 179.141 102.658 1.00 100.27 ? 94  GLU D C   1 
ATOM   7765  O O   . GLU C 3 114 ? 156.520 179.548 103.669 1.00 98.39  ? 94  GLU D O   1 
ATOM   7766  C CB  . GLU C 3 114 ? 156.698 180.088 100.373 1.00 105.04 ? 94  GLU D CB  1 
ATOM   7767  C CG  . GLU C 3 114 ? 157.252 180.822 99.164  1.00 105.36 ? 94  GLU D CG  1 
ATOM   7768  C CD  . GLU C 3 114 ? 158.015 179.905 98.226  1.00 108.76 ? 94  GLU D CD  1 
ATOM   7769  O OE1 . GLU C 3 114 ? 157.393 179.352 97.295  1.00 108.02 ? 94  GLU D OE1 1 
ATOM   7770  O OE2 . GLU C 3 114 ? 159.240 179.748 98.414  1.00 109.72 ? 94  GLU D OE2 1 
ATOM   7771  N N   . ASP C 3 115 ? 157.334 177.843 102.444 1.00 100.78 ? 95  ASP D N   1 
ATOM   7772  C CA  . ASP C 3 115 ? 156.894 176.844 103.412 1.00 99.40  ? 95  ASP D CA  1 
ATOM   7773  C C   . ASP C 3 115 ? 157.632 176.985 104.737 1.00 97.01  ? 95  ASP D C   1 
ATOM   7774  O O   . ASP C 3 115 ? 157.038 176.774 105.799 1.00 95.82  ? 95  ASP D O   1 
ATOM   7775  C CB  . ASP C 3 115 ? 157.080 175.440 102.842 1.00 98.67  ? 95  ASP D CB  1 
ATOM   7776  C CG  . ASP C 3 115 ? 155.794 174.867 102.281 1.00 99.07  ? 95  ASP D CG  1 
ATOM   7777  O OD1 . ASP C 3 115 ? 154.742 175.526 102.420 1.00 98.98  ? 95  ASP D OD1 1 
ATOM   7778  O OD2 . ASP C 3 115 ? 155.833 173.759 101.705 1.00 97.35  ? 95  ASP D OD2 1 
ATOM   7779  N N   . LYS C 3 116 ? 158.915 177.348 104.698 1.00 92.93  ? 96  LYS D N   1 
ATOM   7780  C CA  . LYS C 3 116 ? 159.644 177.611 105.934 1.00 90.95  ? 96  LYS D CA  1 
ATOM   7781  C C   . LYS C 3 116 ? 159.060 178.810 106.672 1.00 93.51  ? 96  LYS D C   1 
ATOM   7782  O O   . LYS C 3 116 ? 158.961 178.801 107.905 1.00 92.14  ? 96  LYS D O   1 
ATOM   7783  C CB  . LYS C 3 116 ? 161.125 177.827 105.628 1.00 91.40  ? 96  LYS D CB  1 
ATOM   7784  C CG  . LYS C 3 116 ? 161.811 176.604 105.037 1.00 93.63  ? 96  LYS D CG  1 
ATOM   7785  C CD  . LYS C 3 116 ? 163.092 176.970 104.304 1.00 97.94  ? 96  LYS D CD  1 
ATOM   7786  C CE  . LYS C 3 116 ? 164.319 176.721 105.163 1.00 92.16  ? 96  LYS D CE  1 
ATOM   7787  N NZ  . LYS C 3 116 ? 165.577 176.865 104.380 1.00 82.66  ? 96  LYS D NZ  1 
ATOM   7788  N N   . VAL C 3 117 ? 158.667 179.852 105.935 1.00 95.62  ? 97  VAL D N   1 
ATOM   7789  C CA  . VAL C 3 117 ? 158.055 181.021 106.563 1.00 96.04  ? 97  VAL D CA  1 
ATOM   7790  C C   . VAL C 3 117 ? 156.729 180.644 107.215 1.00 94.03  ? 97  VAL D C   1 
ATOM   7791  O O   . VAL C 3 117 ? 156.429 181.070 108.339 1.00 93.27  ? 97  VAL D O   1 
ATOM   7792  C CB  . VAL C 3 117 ? 157.885 182.153 105.531 1.00 97.14  ? 97  VAL D CB  1 
ATOM   7793  C CG1 . VAL C 3 117 ? 156.848 183.164 106.000 1.00 97.01  ? 97  VAL D CG1 1 
ATOM   7794  C CG2 . VAL C 3 117 ? 159.218 182.838 105.268 1.00 92.98  ? 97  VAL D CG2 1 
ATOM   7795  N N   . LEU C 3 118 ? 155.913 179.842 106.523 1.00 90.15  ? 98  LEU D N   1 
ATOM   7796  C CA  . LEU C 3 118 ? 154.668 179.372 107.133 1.00 88.97  ? 98  LEU D CA  1 
ATOM   7797  C C   . LEU C 3 118 ? 154.937 178.515 108.363 1.00 90.98  ? 98  LEU D C   1 
ATOM   7798  O O   . LEU C 3 118 ? 154.200 178.595 109.351 1.00 91.50  ? 98  LEU D O   1 
ATOM   7799  C CB  . LEU C 3 118 ? 153.804 178.608 106.125 1.00 92.19  ? 98  LEU D CB  1 
ATOM   7800  C CG  . LEU C 3 118 ? 152.878 179.407 105.197 1.00 96.02  ? 98  LEU D CG  1 
ATOM   7801  C CD1 . LEU C 3 118 ? 153.526 179.805 103.897 1.00 97.65  ? 98  LEU D CD1 1 
ATOM   7802  C CD2 . LEU C 3 118 ? 151.599 178.624 104.923 1.00 92.42  ? 98  LEU D CD2 1 
ATOM   7803  N N   . PHE C 3 119 ? 155.979 177.683 108.324 1.00 91.85  ? 99  PHE D N   1 
ATOM   7804  C CA  . PHE C 3 119 ? 156.322 176.897 109.505 1.00 85.87  ? 99  PHE D CA  1 
ATOM   7805  C C   . PHE C 3 119 ? 156.691 177.798 110.675 1.00 86.40  ? 99  PHE D C   1 
ATOM   7806  O O   . PHE C 3 119 ? 156.267 177.556 111.810 1.00 84.97  ? 99  PHE D O   1 
ATOM   7807  C CB  . PHE C 3 119 ? 157.470 175.936 109.199 1.00 81.37  ? 99  PHE D CB  1 
ATOM   7808  C CG  . PHE C 3 119 ? 157.807 175.022 110.344 1.00 81.80  ? 99  PHE D CG  1 
ATOM   7809  C CD1 . PHE C 3 119 ? 156.984 173.952 110.658 1.00 78.52  ? 99  PHE D CD1 1 
ATOM   7810  C CD2 . PHE C 3 119 ? 158.932 175.243 111.119 1.00 78.51  ? 99  PHE D CD2 1 
ATOM   7811  C CE1 . PHE C 3 119 ? 157.285 173.113 111.713 1.00 67.86  ? 99  PHE D CE1 1 
ATOM   7812  C CE2 . PHE C 3 119 ? 159.237 174.407 112.176 1.00 70.56  ? 99  PHE D CE2 1 
ATOM   7813  C CZ  . PHE C 3 119 ? 158.412 173.342 112.473 1.00 64.48  ? 99  PHE D CZ  1 
ATOM   7814  N N   . GLU C 3 120 ? 157.482 178.842 110.418 1.00 90.12  ? 100 GLU D N   1 
ATOM   7815  C CA  . GLU C 3 120 ? 157.861 179.760 111.489 1.00 88.09  ? 100 GLU D CA  1 
ATOM   7816  C C   . GLU C 3 120 ? 156.644 180.482 112.058 1.00 87.47  ? 100 GLU D C   1 
ATOM   7817  O O   . GLU C 3 120 ? 156.512 180.625 113.280 1.00 88.61  ? 100 GLU D O   1 
ATOM   7818  C CB  . GLU C 3 120 ? 158.895 180.766 110.984 1.00 87.74  ? 100 GLU D CB  1 
ATOM   7819  C CG  . GLU C 3 120 ? 160.191 180.137 110.508 1.00 90.86  ? 100 GLU D CG  1 
ATOM   7820  C CD  . GLU C 3 120 ? 161.383 181.058 110.680 1.00 99.80  ? 100 GLU D CD  1 
ATOM   7821  O OE1 . GLU C 3 120 ? 161.249 182.081 111.383 1.00 100.34 ? 100 GLU D OE1 1 
ATOM   7822  O OE2 . GLU C 3 120 ? 162.454 180.758 110.112 1.00 101.46 ? 100 GLU D OE2 1 
ATOM   7823  N N   . GLN C 3 121 ? 155.741 180.941 111.188 1.00 88.32  ? 101 GLN D N   1 
ATOM   7824  C CA  . GLN C 3 121 ? 154.544 181.629 111.668 1.00 89.98  ? 101 GLN D CA  1 
ATOM   7825  C C   . GLN C 3 121 ? 153.648 180.692 112.472 1.00 89.26  ? 101 GLN D C   1 
ATOM   7826  O O   . GLN C 3 121 ? 153.100 181.083 113.511 1.00 88.63  ? 101 GLN D O   1 
ATOM   7827  C CB  . GLN C 3 121 ? 153.777 182.234 110.494 1.00 93.36  ? 101 GLN D CB  1 
ATOM   7828  C CG  . GLN C 3 121 ? 154.567 183.266 109.708 1.00 92.35  ? 101 GLN D CG  1 
ATOM   7829  C CD  . GLN C 3 121 ? 153.849 183.718 108.453 1.00 95.07  ? 101 GLN D CD  1 
ATOM   7830  O OE1 . GLN C 3 121 ? 153.030 182.988 107.894 1.00 93.71  ? 101 GLN D OE1 1 
ATOM   7831  N NE2 . GLN C 3 121 ? 154.157 184.927 107.999 1.00 97.18  ? 101 GLN D NE2 1 
ATOM   7832  N N   . ALA C 3 122 ? 153.484 179.451 112.008 1.00 89.17  ? 102 ALA D N   1 
ATOM   7833  C CA  . ALA C 3 122 ? 152.673 178.484 112.740 1.00 86.60  ? 102 ALA D CA  1 
ATOM   7834  C C   . ALA C 3 122 ? 153.301 178.146 114.085 1.00 84.80  ? 102 ALA D C   1 
ATOM   7835  O O   . ALA C 3 122 ? 152.591 177.968 115.080 1.00 84.03  ? 102 ALA D O   1 
ATOM   7836  C CB  . ALA C 3 122 ? 152.479 177.221 111.903 1.00 85.30  ? 102 ALA D CB  1 
ATOM   7837  N N   . PHE C 3 123 ? 154.630 178.039 114.131 1.00 82.86  ? 103 PHE D N   1 
ATOM   7838  C CA  . PHE C 3 123 ? 155.310 177.811 115.401 1.00 79.23  ? 103 PHE D CA  1 
ATOM   7839  C C   . PHE C 3 123 ? 155.100 178.980 116.352 1.00 82.53  ? 103 PHE D C   1 
ATOM   7840  O O   . PHE C 3 123 ? 154.881 178.783 117.553 1.00 85.41  ? 103 PHE D O   1 
ATOM   7841  C CB  . PHE C 3 123 ? 156.802 177.576 115.162 1.00 74.86  ? 103 PHE D CB  1 
ATOM   7842  C CG  . PHE C 3 123 ? 157.516 176.978 116.337 1.00 72.02  ? 103 PHE D CG  1 
ATOM   7843  C CD1 . PHE C 3 123 ? 157.582 175.606 116.497 1.00 73.37  ? 103 PHE D CD1 1 
ATOM   7844  C CD2 . PHE C 3 123 ? 158.118 177.786 117.285 1.00 69.85  ? 103 PHE D CD2 1 
ATOM   7845  C CE1 . PHE C 3 123 ? 158.236 175.054 117.576 1.00 66.37  ? 103 PHE D CE1 1 
ATOM   7846  C CE2 . PHE C 3 123 ? 158.774 177.238 118.367 1.00 67.20  ? 103 PHE D CE2 1 
ATOM   7847  C CZ  . PHE C 3 123 ? 158.833 175.871 118.513 1.00 63.34  ? 103 PHE D CZ  1 
ATOM   7848  N N   . SER C 3 124 ? 155.169 180.208 115.835 1.00 85.17  ? 104 SER D N   1 
ATOM   7849  C CA  . SER C 3 124 ? 154.936 181.377 116.678 1.00 86.58  ? 104 SER D CA  1 
ATOM   7850  C C   . SER C 3 124 ? 153.513 181.391 117.221 1.00 89.50  ? 104 SER D C   1 
ATOM   7851  O O   . SER C 3 124 ? 153.290 181.720 118.392 1.00 87.97  ? 104 SER D O   1 
ATOM   7852  C CB  . SER C 3 124 ? 155.224 182.656 115.892 1.00 88.69  ? 104 SER D CB  1 
ATOM   7853  O OG  . SER C 3 124 ? 156.477 182.577 115.236 1.00 91.78  ? 104 SER D OG  1 
ATOM   7854  N N   . PHE C 3 125 ? 152.535 181.037 116.384 1.00 91.94  ? 105 PHE D N   1 
ATOM   7855  C CA  . PHE C 3 125 ? 151.144 181.059 116.830 1.00 89.51  ? 105 PHE D CA  1 
ATOM   7856  C C   . PHE C 3 125 ? 150.850 179.944 117.829 1.00 89.78  ? 105 PHE D C   1 
ATOM   7857  O O   . PHE C 3 125 ? 150.207 180.183 118.858 1.00 89.96  ? 105 PHE D O   1 
ATOM   7858  C CB  . PHE C 3 125 ? 150.199 180.954 115.633 1.00 88.79  ? 105 PHE D CB  1 
ATOM   7859  C CG  . PHE C 3 125 ? 150.289 182.111 114.681 1.00 96.20  ? 105 PHE D CG  1 
ATOM   7860  C CD1 . PHE C 3 125 ? 150.591 183.383 115.139 1.00 98.63  ? 105 PHE D CD1 1 
ATOM   7861  C CD2 . PHE C 3 125 ? 150.054 181.931 113.328 1.00 97.89  ? 105 PHE D CD2 1 
ATOM   7862  C CE1 . PHE C 3 125 ? 150.670 184.450 114.264 1.00 99.08  ? 105 PHE D CE1 1 
ATOM   7863  C CE2 . PHE C 3 125 ? 150.130 182.994 112.448 1.00 99.01  ? 105 PHE D CE2 1 
ATOM   7864  C CZ  . PHE C 3 125 ? 150.439 184.255 112.917 1.00 98.90  ? 105 PHE D CZ  1 
ATOM   7865  N N   . HIS C 3 126 ? 151.310 178.726 117.551 1.00 88.20  ? 106 HIS D N   1 
ATOM   7866  C CA  . HIS C 3 126 ? 150.893 177.539 118.291 1.00 86.74  ? 106 HIS D CA  1 
ATOM   7867  C C   . HIS C 3 126 ? 151.988 176.921 119.145 1.00 85.63  ? 106 HIS D C   1 
ATOM   7868  O O   . HIS C 3 126 ? 151.700 176.427 120.237 1.00 85.54  ? 106 HIS D O   1 
ATOM   7869  C CB  . HIS C 3 126 ? 150.363 176.482 117.317 1.00 83.69  ? 106 HIS D CB  1 
ATOM   7870  C CG  . HIS C 3 126 ? 149.413 177.025 116.296 1.00 87.28  ? 106 HIS D CG  1 
ATOM   7871  N ND1 . HIS C 3 126 ? 148.161 177.499 116.622 1.00 85.91  ? 106 HIS D ND1 1 
ATOM   7872  C CD2 . HIS C 3 126 ? 149.536 177.178 114.956 1.00 86.82  ? 106 HIS D CD2 1 
ATOM   7873  C CE1 . HIS C 3 126 ? 147.551 177.915 115.526 1.00 83.85  ? 106 HIS D CE1 1 
ATOM   7874  N NE2 . HIS C 3 126 ? 148.363 177.731 114.502 1.00 87.34  ? 106 HIS D NE2 1 
ATOM   7875  N N   . GLY C 3 127 ? 153.234 176.921 118.682 1.00 80.94  ? 107 GLY D N   1 
ATOM   7876  C CA  . GLY C 3 127 ? 154.308 176.309 119.439 1.00 72.88  ? 107 GLY D CA  1 
ATOM   7877  C C   . GLY C 3 127 ? 154.732 174.965 118.883 1.00 74.85  ? 107 GLY D C   1 
ATOM   7878  O O   . GLY C 3 127 ? 154.764 174.774 117.665 1.00 76.56  ? 107 GLY D O   1 
ATOM   7879  N N   . LYS C 3 128 ? 155.055 174.020 119.768 1.00 70.40  ? 108 LYS D N   1 
ATOM   7880  C CA  . LYS C 3 128 ? 155.481 172.685 119.365 1.00 63.93  ? 108 LYS D CA  1 
ATOM   7881  C C   . LYS C 3 128 ? 154.317 171.710 119.243 1.00 64.25  ? 108 LYS D C   1 
ATOM   7882  O O   . LYS C 3 128 ? 154.502 170.501 119.429 1.00 63.23  ? 108 LYS D O   1 
ATOM   7883  C CB  . LYS C 3 128 ? 156.529 172.144 120.338 1.00 57.76  ? 108 LYS D CB  1 
ATOM   7884  C CG  . LYS C 3 128 ? 157.927 172.698 120.115 1.00 60.64  ? 108 LYS D CG  1 
ATOM   7885  C CD  . LYS C 3 128 ? 158.893 171.616 119.650 1.00 58.93  ? 108 LYS D CD  1 
ATOM   7886  C CE  . LYS C 3 128 ? 160.241 172.205 119.241 1.00 56.26  ? 108 LYS D CE  1 
ATOM   7887  N NZ  . LYS C 3 128 ? 161.094 171.229 118.500 1.00 36.97  ? 108 LYS D NZ  1 
ATOM   7888  N N   . THR C 3 129 ? 153.117 172.207 118.952 1.00 69.74  ? 109 THR D N   1 
ATOM   7889  C CA  . THR C 3 129 ? 151.961 171.362 118.659 1.00 69.26  ? 109 THR D CA  1 
ATOM   7890  C C   . THR C 3 129 ? 151.901 171.195 117.145 1.00 66.77  ? 109 THR D C   1 
ATOM   7891  O O   . THR C 3 129 ? 151.272 171.983 116.440 1.00 71.98  ? 109 THR D O   1 
ATOM   7892  C CB  . THR C 3 129 ? 150.675 171.971 119.210 1.00 72.79  ? 109 THR D CB  1 
ATOM   7893  O OG1 . THR C 3 129 ? 150.921 172.521 120.510 1.00 77.61  ? 109 THR D OG1 1 
ATOM   7894  C CG2 . THR C 3 129 ? 149.586 170.913 119.309 1.00 70.04  ? 109 THR D CG2 1 
ATOM   7895  N N   . PHE C 3 130 ? 152.571 170.155 116.643 1.00 62.33  ? 110 PHE D N   1 
ATOM   7896  C CA  . PHE C 3 130 ? 152.600 169.908 115.206 1.00 63.45  ? 110 PHE D CA  1 
ATOM   7897  C C   . PHE C 3 130 ? 151.233 169.520 114.660 1.00 70.11  ? 110 PHE D C   1 
ATOM   7898  O O   . PHE C 3 130 ? 150.990 169.681 113.459 1.00 70.32  ? 110 PHE D O   1 
ATOM   7899  C CB  . PHE C 3 130 ? 153.630 168.824 114.884 1.00 58.11  ? 110 PHE D CB  1 
ATOM   7900  C CG  . PHE C 3 130 ? 155.006 169.124 115.406 1.00 54.26  ? 110 PHE D CG  1 
ATOM   7901  C CD1 . PHE C 3 130 ? 155.753 170.158 114.872 1.00 55.16  ? 110 PHE D CD1 1 
ATOM   7902  C CD2 . PHE C 3 130 ? 155.550 168.378 116.435 1.00 43.38  ? 110 PHE D CD2 1 
ATOM   7903  C CE1 . PHE C 3 130 ? 157.016 170.438 115.355 1.00 51.36  ? 110 PHE D CE1 1 
ATOM   7904  C CE2 . PHE C 3 130 ? 156.811 168.655 116.919 1.00 36.03  ? 110 PHE D CE2 1 
ATOM   7905  C CZ  . PHE C 3 130 ? 157.544 169.683 116.379 1.00 38.07  ? 110 PHE D CZ  1 
ATOM   7906  N N   . HIS C 3 131 ? 150.337 169.025 115.516 1.00 76.29  ? 111 HIS D N   1 
ATOM   7907  C CA  . HIS C 3 131 ? 148.969 168.750 115.089 1.00 76.40  ? 111 HIS D CA  1 
ATOM   7908  C C   . HIS C 3 131 ? 148.275 170.023 114.624 1.00 75.87  ? 111 HIS D C   1 
ATOM   7909  O O   . HIS C 3 131 ? 147.575 170.022 113.605 1.00 78.74  ? 111 HIS D O   1 
ATOM   7910  C CB  . HIS C 3 131 ? 148.192 168.100 116.234 1.00 81.26  ? 111 HIS D CB  1 
ATOM   7911  C CG  . HIS C 3 131 ? 146.881 167.508 115.822 1.00 91.46  ? 111 HIS D CG  1 
ATOM   7912  N ND1 . HIS C 3 131 ? 146.770 166.244 115.286 1.00 93.56  ? 111 HIS D ND1 1 
ATOM   7913  C CD2 . HIS C 3 131 ? 145.622 168.005 115.876 1.00 94.30  ? 111 HIS D CD2 1 
ATOM   7914  C CE1 . HIS C 3 131 ? 145.501 165.988 115.024 1.00 94.97  ? 111 HIS D CE1 1 
ATOM   7915  N NE2 . HIS C 3 131 ? 144.783 167.041 115.372 1.00 95.73  ? 111 HIS D NE2 1 
ATOM   7916  N N   . ARG C 3 132 ? 148.456 171.121 115.361 1.00 74.72  ? 112 ARG D N   1 
ATOM   7917  C CA  . ARG C 3 132 ? 147.891 172.403 114.958 1.00 74.21  ? 112 ARG D CA  1 
ATOM   7918  C C   . ARG C 3 132 ? 148.679 173.047 113.826 1.00 74.21  ? 112 ARG D C   1 
ATOM   7919  O O   . ARG C 3 132 ? 148.102 173.779 113.015 1.00 78.36  ? 112 ARG D O   1 
ATOM   7920  C CB  . ARG C 3 132 ? 147.830 173.352 116.154 1.00 75.50  ? 112 ARG D CB  1 
ATOM   7921  C CG  . ARG C 3 132 ? 146.710 173.049 117.130 1.00 76.74  ? 112 ARG D CG  1 
ATOM   7922  C CD  . ARG C 3 132 ? 146.534 174.181 118.125 1.00 77.00  ? 112 ARG D CD  1 
ATOM   7923  N NE  . ARG C 3 132 ? 145.496 173.891 119.106 1.00 81.44  ? 112 ARG D NE  1 
ATOM   7924  C CZ  . ARG C 3 132 ? 145.237 174.644 120.166 1.00 82.87  ? 112 ARG D CZ  1 
ATOM   7925  N NH1 . ARG C 3 132 ? 145.929 175.743 120.418 1.00 85.14  ? 112 ARG D NH1 1 
ATOM   7926  N NH2 . ARG C 3 132 ? 144.261 174.285 120.994 1.00 79.40  ? 112 ARG D NH2 1 
ATOM   7927  N N   . ILE C 3 133 ? 149.990 172.804 113.763 1.00 73.84  ? 113 ILE D N   1 
ATOM   7928  C CA  . ILE C 3 133 ? 150.795 173.348 112.674 1.00 73.12  ? 113 ILE D CA  1 
ATOM   7929  C C   . ILE C 3 133 ? 150.376 172.735 111.344 1.00 75.36  ? 113 ILE D C   1 
ATOM   7930  O O   . ILE C 3 133 ? 150.356 173.413 110.310 1.00 77.41  ? 113 ILE D O   1 
ATOM   7931  C CB  . ILE C 3 133 ? 152.292 173.130 112.959 1.00 70.83  ? 113 ILE D CB  1 
ATOM   7932  C CG1 . ILE C 3 133 ? 152.707 173.883 114.224 1.00 73.57  ? 113 ILE D CG1 1 
ATOM   7933  C CG2 . ILE C 3 133 ? 153.138 173.580 111.780 1.00 69.05  ? 113 ILE D CG2 1 
ATOM   7934  C CD1 . ILE C 3 133 ? 154.171 173.745 114.568 1.00 68.16  ? 113 ILE D CD1 1 
ATOM   7935  N N   . GLN C 3 134 ? 150.026 171.446 111.348 1.00 77.53  ? 114 GLN D N   1 
ATOM   7936  C CA  . GLN C 3 134 ? 149.580 170.793 110.124 1.00 78.68  ? 114 GLN D CA  1 
ATOM   7937  C C   . GLN C 3 134 ? 148.249 171.339 109.621 1.00 82.82  ? 114 GLN D C   1 
ATOM   7938  O O   . GLN C 3 134 ? 147.937 171.175 108.437 1.00 85.59  ? 114 GLN D O   1 
ATOM   7939  C CB  . GLN C 3 134 ? 149.471 169.283 110.343 1.00 76.90  ? 114 GLN D CB  1 
ATOM   7940  C CG  . GLN C 3 134 ? 149.419 168.472 109.060 1.00 74.61  ? 114 GLN D CG  1 
ATOM   7941  C CD  . GLN C 3 134 ? 149.046 167.027 109.299 1.00 72.16  ? 114 GLN D CD  1 
ATOM   7942  O OE1 . GLN C 3 134 ? 148.187 166.724 110.125 1.00 71.83  ? 114 GLN D OE1 1 
ATOM   7943  N NE2 . GLN C 3 134 ? 149.688 166.124 108.569 1.00 69.51  ? 114 GLN D NE2 1 
ATOM   7944  N N   . GLN C 3 135 ? 147.455 171.975 110.486 1.00 84.34  ? 115 GLN D N   1 
ATOM   7945  C CA  . GLN C 3 135 ? 146.179 172.528 110.040 1.00 85.98  ? 115 GLN D CA  1 
ATOM   7946  C C   . GLN C 3 135 ? 146.383 173.605 108.982 1.00 86.06  ? 115 GLN D C   1 
ATOM   7947  O O   . GLN C 3 135 ? 145.667 173.639 107.975 1.00 89.37  ? 115 GLN D O   1 
ATOM   7948  C CB  . GLN C 3 135 ? 145.399 173.086 111.229 1.00 83.66  ? 115 GLN D CB  1 
ATOM   7949  C CG  . GLN C 3 135 ? 144.766 172.024 112.111 1.00 86.26  ? 115 GLN D CG  1 
ATOM   7950  C CD  . GLN C 3 135 ? 144.116 172.610 113.347 1.00 91.04  ? 115 GLN D CD  1 
ATOM   7951  O OE1 . GLN C 3 135 ? 144.183 173.816 113.585 1.00 88.29  ? 115 GLN D OE1 1 
ATOM   7952  N NE2 . GLN C 3 135 ? 143.478 171.758 114.141 1.00 92.33  ? 115 GLN D NE2 1 
ATOM   7953  N N   . MET C 3 136 ? 147.352 174.492 109.190 1.00 83.58  ? 116 MET D N   1 
ATOM   7954  C CA  . MET C 3 136 ? 147.684 175.510 108.205 1.00 87.33  ? 116 MET D CA  1 
ATOM   7955  C C   . MET C 3 136 ? 148.828 175.087 107.291 1.00 88.45  ? 116 MET D C   1 
ATOM   7956  O O   . MET C 3 136 ? 149.190 175.837 106.379 1.00 90.45  ? 116 MET D O   1 
ATOM   7957  C CB  . MET C 3 136 ? 148.010 176.835 108.907 1.00 92.03  ? 116 MET D CB  1 
ATOM   7958  C CG  . MET C 3 136 ? 149.476 177.091 109.197 1.00 95.22  ? 116 MET D CG  1 
ATOM   7959  S SD  . MET C 3 136 ? 149.686 178.700 109.984 1.00 107.91 ? 116 MET D SD  1 
ATOM   7960  C CE  . MET C 3 136 ? 151.134 179.314 109.133 1.00 92.88  ? 116 MET D CE  1 
ATOM   7961  N N   . LEU C 3 137 ? 149.384 173.896 107.502 1.00 88.97  ? 117 LEU D N   1 
ATOM   7962  C CA  . LEU C 3 137 ? 150.380 173.299 106.612 1.00 90.45  ? 117 LEU D CA  1 
ATOM   7963  C C   . LEU C 3 137 ? 149.943 171.873 106.295 1.00 87.89  ? 117 LEU D C   1 
ATOM   7964  O O   . LEU C 3 137 ? 150.548 170.903 106.765 1.00 85.31  ? 117 LEU D O   1 
ATOM   7965  C CB  . LEU C 3 137 ? 151.772 173.323 107.244 1.00 87.50  ? 117 LEU D CB  1 
ATOM   7966  C CG  . LEU C 3 137 ? 152.788 174.286 106.635 1.00 84.47  ? 117 LEU D CG  1 
ATOM   7967  C CD1 . LEU C 3 137 ? 154.107 174.211 107.382 1.00 82.70  ? 117 LEU D CD1 1 
ATOM   7968  C CD2 . LEU C 3 137 ? 152.988 173.973 105.164 1.00 85.57  ? 117 LEU D CD2 1 
ATOM   7969  N N   . PRO C 3 138 ? 148.883 171.711 105.496 1.00 87.94  ? 118 PRO D N   1 
ATOM   7970  C CA  . PRO C 3 138 ? 148.332 170.367 105.276 1.00 87.94  ? 118 PRO D CA  1 
ATOM   7971  C C   . PRO C 3 138 ? 149.092 169.543 104.252 1.00 85.88  ? 118 PRO D C   1 
ATOM   7972  O O   . PRO C 3 138 ? 148.875 168.326 104.183 1.00 83.78  ? 118 PRO D O   1 
ATOM   7973  C CB  . PRO C 3 138 ? 146.902 170.650 104.802 1.00 86.59  ? 118 PRO D CB  1 
ATOM   7974  C CG  . PRO C 3 138 ? 146.987 171.992 104.140 1.00 86.16  ? 118 PRO D CG  1 
ATOM   7975  C CD  . PRO C 3 138 ? 148.167 172.738 104.719 1.00 86.16  ? 118 PRO D CD  1 
ATOM   7976  N N   . ASP C 3 139 ? 149.966 170.157 103.457 1.00 85.94  ? 119 ASP D N   1 
ATOM   7977  C CA  . ASP C 3 139 ? 150.740 169.420 102.468 1.00 84.16  ? 119 ASP D CA  1 
ATOM   7978  C C   . ASP C 3 139 ? 151.905 168.654 103.079 1.00 84.07  ? 119 ASP D C   1 
ATOM   7979  O O   . ASP C 3 139 ? 152.541 167.863 102.374 1.00 85.19  ? 119 ASP D O   1 
ATOM   7980  C CB  . ASP C 3 139 ? 151.264 170.374 101.392 1.00 88.41  ? 119 ASP D CB  1 
ATOM   7981  C CG  . ASP C 3 139 ? 151.800 171.670 101.970 1.00 92.99  ? 119 ASP D CG  1 
ATOM   7982  O OD1 . ASP C 3 139 ? 151.152 172.231 102.879 1.00 92.88  ? 119 ASP D OD1 1 
ATOM   7983  O OD2 . ASP C 3 139 ? 152.868 172.129 101.515 1.00 90.46  ? 119 ASP D OD2 1 
ATOM   7984  N N   . LYS C 3 140 ? 152.200 168.867 104.358 1.00 82.24  ? 120 LYS D N   1 
ATOM   7985  C CA  . LYS C 3 140 ? 153.313 168.218 105.036 1.00 74.98  ? 120 LYS D CA  1 
ATOM   7986  C C   . LYS C 3 140 ? 152.778 167.265 106.095 1.00 72.92  ? 120 LYS D C   1 
ATOM   7987  O O   . LYS C 3 140 ? 151.861 167.614 106.845 1.00 76.21  ? 120 LYS D O   1 
ATOM   7988  C CB  . LYS C 3 140 ? 154.242 169.250 105.683 1.00 70.82  ? 120 LYS D CB  1 
ATOM   7989  C CG  . LYS C 3 140 ? 154.809 170.290 104.727 1.00 78.97  ? 120 LYS D CG  1 
ATOM   7990  C CD  . LYS C 3 140 ? 155.172 169.689 103.380 1.00 83.36  ? 120 LYS D CD  1 
ATOM   7991  C CE  . LYS C 3 140 ? 156.396 170.359 102.786 1.00 86.04  ? 120 LYS D CE  1 
ATOM   7992  N NZ  . LYS C 3 140 ? 157.655 169.710 103.237 1.00 87.37  ? 120 LYS D NZ  1 
ATOM   7993  N N   . SER C 3 141 ? 153.347 166.064 106.148 1.00 67.13  ? 121 SER D N   1 
ATOM   7994  C CA  . SER C 3 141 ? 152.988 165.111 107.184 1.00 60.77  ? 121 SER D CA  1 
ATOM   7995  C C   . SER C 3 141 ? 153.616 165.514 108.514 1.00 55.42  ? 121 SER D C   1 
ATOM   7996  O O   . SER C 3 141 ? 154.540 166.329 108.574 1.00 56.65  ? 121 SER D O   1 
ATOM   7997  C CB  . SER C 3 141 ? 153.433 163.702 106.792 1.00 59.57  ? 121 SER D CB  1 
ATOM   7998  O OG  . SER C 3 141 ? 154.842 163.628 106.676 1.00 57.55  ? 121 SER D OG  1 
ATOM   7999  N N   . ILE C 3 142 ? 153.097 164.929 109.597 1.00 53.30  ? 122 ILE D N   1 
ATOM   8000  C CA  . ILE C 3 142 ? 153.615 165.245 110.926 1.00 52.82  ? 122 ILE D CA  1 
ATOM   8001  C C   . ILE C 3 142 ? 155.066 164.800 111.052 1.00 50.28  ? 122 ILE D C   1 
ATOM   8002  O O   . ILE C 3 142 ? 155.890 165.486 111.670 1.00 46.93  ? 122 ILE D O   1 
ATOM   8003  C CB  . ILE C 3 142 ? 152.725 164.614 112.014 1.00 52.34  ? 122 ILE D CB  1 
ATOM   8004  C CG1 . ILE C 3 142 ? 151.342 165.265 112.010 1.00 57.51  ? 122 ILE D CG1 1 
ATOM   8005  C CG2 . ILE C 3 142 ? 153.361 164.765 113.385 1.00 53.62  ? 122 ILE D CG2 1 
ATOM   8006  C CD1 . ILE C 3 142 ? 150.429 164.761 113.101 1.00 56.36  ? 122 ILE D CD1 1 
ATOM   8007  N N   . ALA C 3 143 ? 155.407 163.652 110.461 1.00 50.05  ? 123 ALA D N   1 
ATOM   8008  C CA  . ALA C 3 143 ? 156.795 163.203 110.465 1.00 39.04  ? 123 ALA D CA  1 
ATOM   8009  C C   . ALA C 3 143 ? 157.705 164.189 109.746 1.00 44.21  ? 123 ALA D C   1 
ATOM   8010  O O   . ALA C 3 143 ? 158.880 164.323 110.102 1.00 41.08  ? 123 ALA D O   1 
ATOM   8011  C CB  . ALA C 3 143 ? 156.901 161.819 109.828 1.00 33.82  ? 123 ALA D CB  1 
ATOM   8012  N N   . SER C 3 144 ? 157.185 164.883 108.731 1.00 52.66  ? 124 SER D N   1 
ATOM   8013  C CA  . SER C 3 144 ? 157.976 165.905 108.056 1.00 50.51  ? 124 SER D CA  1 
ATOM   8014  C C   . SER C 3 144 ? 158.094 167.169 108.896 1.00 51.84  ? 124 SER D C   1 
ATOM   8015  O O   . SER C 3 144 ? 159.083 167.900 108.778 1.00 56.33  ? 124 SER D O   1 
ATOM   8016  C CB  . SER C 3 144 ? 157.366 166.230 106.694 1.00 58.16  ? 124 SER D CB  1 
ATOM   8017  O OG  . SER C 3 144 ? 158.174 167.153 105.985 1.00 71.63  ? 124 SER D OG  1 
ATOM   8018  N N   . LEU C 3 145 ? 157.098 167.447 109.739 1.00 49.58  ? 125 LEU D N   1 
ATOM   8019  C CA  . LEU C 3 145 ? 157.170 168.609 110.618 1.00 50.46  ? 125 LEU D CA  1 
ATOM   8020  C C   . LEU C 3 145 ? 158.105 168.365 111.796 1.00 47.35  ? 125 LEU D C   1 
ATOM   8021  O O   . LEU C 3 145 ? 158.806 169.284 112.233 1.00 49.18  ? 125 LEU D O   1 
ATOM   8022  C CB  . LEU C 3 145 ? 155.772 168.980 111.111 1.00 51.60  ? 125 LEU D CB  1 
ATOM   8023  C CG  . LEU C 3 145 ? 154.740 169.301 110.028 1.00 54.37  ? 125 LEU D CG  1 
ATOM   8024  C CD1 . LEU C 3 145 ? 153.345 169.397 110.622 1.00 57.59  ? 125 LEU D CD1 1 
ATOM   8025  C CD2 . LEU C 3 145 ? 155.104 170.581 109.297 1.00 55.89  ? 125 LEU D CD2 1 
ATOM   8026  N N   . VAL C 3 146 ? 158.126 167.140 112.328 1.00 45.74  ? 126 VAL D N   1 
ATOM   8027  C CA  . VAL C 3 146 ? 159.028 166.826 113.431 1.00 38.73  ? 126 VAL D CA  1 
ATOM   8028  C C   . VAL C 3 146 ? 160.475 166.830 112.954 1.00 39.95  ? 126 VAL D C   1 
ATOM   8029  O O   . VAL C 3 146 ? 161.377 167.290 113.665 1.00 44.87  ? 126 VAL D O   1 
ATOM   8030  C CB  . VAL C 3 146 ? 158.645 165.480 114.072 1.00 31.83  ? 126 VAL D CB  1 
ATOM   8031  C CG1 . VAL C 3 146 ? 159.610 165.130 115.189 1.00 27.39  ? 126 VAL D CG1 1 
ATOM   8032  C CG2 . VAL C 3 146 ? 157.225 165.529 114.598 1.00 35.61  ? 126 VAL D CG2 1 
ATOM   8033  N N   . LYS C 3 147 ? 160.724 166.320 111.746 1.00 38.57  ? 127 LYS D N   1 
ATOM   8034  C CA  . LYS C 3 147 ? 162.076 166.347 111.200 1.00 39.26  ? 127 LYS D CA  1 
ATOM   8035  C C   . LYS C 3 147 ? 162.534 167.772 110.912 1.00 45.12  ? 127 LYS D C   1 
ATOM   8036  O O   . LYS C 3 147 ? 163.728 168.072 111.019 1.00 44.98  ? 127 LYS D O   1 
ATOM   8037  C CB  . LYS C 3 147 ? 162.141 165.489 109.936 1.00 39.88  ? 127 LYS D CB  1 
ATOM   8038  C CG  . LYS C 3 147 ? 163.432 165.611 109.149 1.00 41.45  ? 127 LYS D CG  1 
ATOM   8039  C CD  . LYS C 3 147 ? 163.751 164.322 108.417 1.00 41.14  ? 127 LYS D CD  1 
ATOM   8040  C CE  . LYS C 3 147 ? 163.648 164.497 106.916 1.00 55.00  ? 127 LYS D CE  1 
ATOM   8041  N NZ  . LYS C 3 147 ? 164.908 165.032 106.333 1.00 57.67  ? 127 LYS D NZ  1 
ATOM   8042  N N   . PHE C 3 148 ? 161.608 168.661 110.566 1.00 49.20  ? 128 PHE D N   1 
ATOM   8043  C CA  . PHE C 3 148 ? 161.932 170.058 110.298 1.00 51.16  ? 128 PHE D CA  1 
ATOM   8044  C C   . PHE C 3 148 ? 161.893 170.897 111.574 1.00 55.97  ? 128 PHE D C   1 
ATOM   8045  O O   . PHE C 3 148 ? 162.016 170.376 112.683 1.00 50.53  ? 128 PHE D O   1 
ATOM   8046  C CB  . PHE C 3 148 ? 160.966 170.636 109.262 1.00 56.97  ? 128 PHE D CB  1 
ATOM   8047  C CG  . PHE C 3 148 ? 161.185 172.095 108.968 1.00 68.14  ? 128 PHE D CG  1 
ATOM   8048  C CD1 . PHE C 3 148 ? 162.453 172.594 108.737 1.00 69.72  ? 128 PHE D CD1 1 
ATOM   8049  C CD2 . PHE C 3 148 ? 160.118 172.969 108.921 1.00 69.38  ? 128 PHE D CD2 1 
ATOM   8050  C CE1 . PHE C 3 148 ? 162.639 173.937 108.467 1.00 61.92  ? 128 PHE D CE1 1 
ATOM   8051  C CD  . LYS C 3 153 ? 165.479 171.298 118.881 1.00 38.50  ? 133 LYS D CD  1 
ATOM   8052  C CE  . LYS C 3 153 ? 164.591 170.921 120.057 1.00 50.37  ? 133 LYS D CE  1 
ATOM   8053  N NZ  . LYS C 3 153 ? 165.055 171.587 121.301 1.00 46.75  ? 133 LYS D NZ  1 
ATOM   8054  N N   . LYS C 3 154 ? 167.619 175.001 116.183 1.00 82.47  ? 134 LYS D N   1 
ATOM   8055  C CA  . LYS C 3 154 ? 168.980 175.522 116.237 1.00 85.85  ? 134 LYS D CA  1 
ATOM   8056  C C   . LYS C 3 154 ? 168.982 177.046 116.212 1.00 92.38  ? 134 LYS D C   1 
ATOM   8057  O O   . LYS C 3 154 ? 169.883 177.683 116.759 1.00 93.98  ? 134 LYS D O   1 
ATOM   8058  C CB  . LYS C 3 154 ? 169.812 174.982 115.073 1.00 85.78  ? 134 LYS D CB  1 
ATOM   8059  C CG  . LYS C 3 154 ? 169.424 173.584 114.617 1.00 87.43  ? 134 LYS D CG  1 
ATOM   8060  C CD  . LYS C 3 154 ? 169.830 173.334 113.169 1.00 84.54  ? 134 LYS D CD  1 
ATOM   8061  C CE  . LYS C 3 154 ? 171.149 174.012 112.827 1.00 82.02  ? 134 LYS D CE  1 
ATOM   8062  N NZ  . LYS C 3 154 ? 171.709 173.525 111.535 1.00 77.88  ? 134 LYS D NZ  1 
ATOM   8063  N N   . THR C 3 155 ? 167.971 177.623 115.571 1.00 95.68  ? 135 THR D N   1 
ATOM   8064  C CA  . THR C 3 155 ? 167.859 179.074 115.457 1.00 91.82  ? 135 THR D CA  1 
ATOM   8065  C C   . THR C 3 155 ? 166.560 179.577 116.080 1.00 84.59  ? 135 THR D C   1 
ATOM   8066  O O   . THR C 3 155 ? 165.480 179.396 115.518 1.00 83.90  ? 135 THR D O   1 
ATOM   8067  C CB  . THR C 3 155 ? 167.924 179.530 113.989 1.00 89.58  ? 135 THR D CB  1 
ATOM   8068  O OG1 . THR C 3 155 ? 167.010 178.756 113.204 1.00 88.38  ? 135 THR D OG1 1 
ATOM   8069  C CG2 . THR C 3 155 ? 169.330 179.351 113.440 1.00 87.80  ? 135 THR D CG2 1 
ATOM   8070  N N   . PRO D 2 7   ? 145.579 175.359 177.088 1.00 104.77 ? 23  PRO E N   1 
ATOM   8071  C CA  . PRO D 2 7   ? 146.571 175.963 176.196 1.00 100.62 ? 23  PRO E CA  1 
ATOM   8072  C C   . PRO D 2 7   ? 145.945 176.526 174.924 1.00 94.06  ? 23  PRO E C   1 
ATOM   8073  O O   . PRO D 2 7   ? 146.548 176.453 173.854 1.00 90.71  ? 23  PRO E O   1 
ATOM   8074  C CB  . PRO D 2 7   ? 147.504 174.793 175.875 1.00 102.61 ? 23  PRO E CB  1 
ATOM   8075  C CG  . PRO D 2 7   ? 146.670 173.543 176.102 1.00 104.53 ? 23  PRO E CG  1 
ATOM   8076  C CD  . PRO D 2 7   ? 145.391 173.928 176.803 1.00 102.92 ? 23  PRO E CD  1 
ATOM   8077  N N   . GLY D 2 8   ? 144.744 177.084 175.050 1.00 89.23  ? 24  GLY E N   1 
ATOM   8078  C CA  . GLY D 2 8   ? 144.062 177.628 173.897 1.00 82.41  ? 24  GLY E CA  1 
ATOM   8079  C C   . GLY D 2 8   ? 144.666 178.936 173.426 1.00 78.71  ? 24  GLY E C   1 
ATOM   8080  O O   . GLY D 2 8   ? 145.485 179.565 174.098 1.00 74.51  ? 24  GLY E O   1 
ATOM   8081  N N   . ALA D 2 9   ? 144.246 179.349 172.233 1.00 69.18  ? 25  ALA E N   1 
ATOM   8082  C CA  . ALA D 2 9   ? 144.709 180.599 171.645 1.00 54.67  ? 25  ALA E CA  1 
ATOM   8083  C C   . ALA D 2 9   ? 143.948 181.765 172.263 1.00 52.14  ? 25  ALA E C   1 
ATOM   8084  O O   . ALA D 2 9   ? 142.720 181.841 172.154 1.00 53.45  ? 25  ALA E O   1 
ATOM   8085  C CB  . ALA D 2 9   ? 144.527 180.571 170.130 1.00 48.44  ? 25  ALA E CB  1 
ATOM   8086  N N   . SER D 2 10  ? 144.676 182.671 172.908 1.00 51.01  ? 26  SER E N   1 
ATOM   8087  C CA  . SER D 2 10  ? 144.053 183.787 173.603 1.00 54.81  ? 26  SER E CA  1 
ATOM   8088  C C   . SER D 2 10  ? 143.451 184.782 172.618 1.00 53.19  ? 26  SER E C   1 
ATOM   8089  O O   . SER D 2 10  ? 143.880 184.895 171.468 1.00 51.31  ? 26  SER E O   1 
ATOM   8090  C CB  . SER D 2 10  ? 145.070 184.494 174.498 1.00 52.48  ? 26  SER E CB  1 
ATOM   8091  O OG  . SER D 2 10  ? 145.405 183.698 175.620 1.00 52.50  ? 26  SER E OG  1 
ATOM   8092  N N   . MET D 2 11  ? 142.435 185.508 173.088 1.00 55.84  ? 27  MET E N   1 
ATOM   8093  C CA  . MET D 2 11  ? 141.800 186.559 172.308 1.00 56.95  ? 27  MET E CA  1 
ATOM   8094  C C   . MET D 2 11  ? 141.985 187.946 172.905 1.00 54.68  ? 27  MET E C   1 
ATOM   8095  O O   . MET D 2 11  ? 141.920 188.933 172.167 1.00 55.09  ? 27  MET E O   1 
ATOM   8096  C CB  . MET D 2 11  ? 140.297 186.276 172.157 1.00 61.01  ? 27  MET E CB  1 
ATOM   8097  C CG  . MET D 2 11  ? 139.592 187.139 171.121 1.00 64.30  ? 27  MET E CG  1 
ATOM   8098  S SD  . MET D 2 11  ? 139.512 186.363 169.496 1.00 83.03  ? 27  MET E SD  1 
ATOM   8099  C CE  . MET D 2 11  ? 139.444 184.630 169.944 1.00 62.70  ? 27  MET E CE  1 
ATOM   8100  N N   . ASP D 2 12  ? 142.226 188.044 174.209 1.00 54.43  ? 28  ASP E N   1 
ATOM   8101  C CA  . ASP D 2 12  ? 142.457 189.322 174.867 1.00 54.77  ? 28  ASP E CA  1 
ATOM   8102  C C   . ASP D 2 12  ? 143.915 189.753 174.821 1.00 53.20  ? 28  ASP E C   1 
ATOM   8103  O O   . ASP D 2 12  ? 144.251 190.808 175.369 1.00 50.24  ? 28  ASP E O   1 
ATOM   8104  C CB  . ASP D 2 12  ? 141.988 189.256 176.325 1.00 57.39  ? 28  ASP E CB  1 
ATOM   8105  C CG  . ASP D 2 12  ? 142.566 188.068 177.072 1.00 60.11  ? 28  ASP E CG  1 
ATOM   8106  O OD1 . ASP D 2 12  ? 142.729 186.995 176.453 1.00 59.55  ? 28  ASP E OD1 1 
ATOM   8107  O OD2 . ASP D 2 12  ? 142.857 188.206 178.279 1.00 57.07  ? 28  ASP E OD2 1 
ATOM   8108  N N   . GLU D 2 13  ? 144.784 188.967 174.190 1.00 48.76  ? 29  GLU E N   1 
ATOM   8109  C CA  . GLU D 2 13  ? 146.208 189.256 174.123 1.00 39.82  ? 29  GLU E CA  1 
ATOM   8110  C C   . GLU D 2 13  ? 146.678 189.153 172.682 1.00 34.88  ? 29  GLU E C   1 
ATOM   8111  O O   . GLU D 2 13  ? 146.418 188.148 172.015 1.00 38.17  ? 29  GLU E O   1 
ATOM   8112  C CB  . GLU D 2 13  ? 147.010 188.288 174.997 1.00 37.08  ? 29  GLU E CB  1 
ATOM   8113  C CG  . GLU D 2 13  ? 146.602 188.265 176.454 1.00 38.97  ? 29  GLU E CG  1 
ATOM   8114  C CD  . GLU D 2 13  ? 147.431 187.295 177.267 1.00 39.32  ? 29  GLU E CD  1 
ATOM   8115  O OE1 . GLU D 2 13  ? 148.275 186.592 176.674 1.00 34.73  ? 29  GLU E OE1 1 
ATOM   8116  O OE2 . GLU D 2 13  ? 147.240 187.236 178.499 1.00 38.34  ? 29  GLU E OE2 1 
ATOM   8117  N N   . ASN D 2 14  ? 147.371 190.185 172.206 1.00 27.61  ? 30  ASN E N   1 
ATOM   8118  C CA  . ASN D 2 14  ? 148.051 190.135 170.921 1.00 25.55  ? 30  ASN E CA  1 
ATOM   8119  C C   . ASN D 2 14  ? 149.461 190.681 171.079 1.00 22.69  ? 30  ASN E C   1 
ATOM   8120  O O   . ASN D 2 14  ? 149.694 191.610 171.855 1.00 22.87  ? 30  ASN E O   1 
ATOM   8121  C CB  . ASN D 2 14  ? 147.292 190.910 169.834 1.00 25.93  ? 30  ASN E CB  1 
ATOM   8122  C CG  . ASN D 2 14  ? 147.022 192.343 170.216 1.00 27.18  ? 30  ASN E CG  1 
ATOM   8123  O OD1 . ASN D 2 14  ? 146.663 192.637 171.354 1.00 32.32  ? 30  ASN E OD1 1 
ATOM   8124  N ND2 . ASN D 2 14  ? 147.176 193.246 169.257 1.00 23.30  ? 30  ASN E ND2 1 
ATOM   8125  N N   . TYR D 2 15  ? 150.396 190.098 170.332 1.00 22.07  ? 31  TYR E N   1 
ATOM   8126  C CA  . TYR D 2 15  ? 151.815 190.401 170.465 1.00 15.60  ? 31  TYR E CA  1 
ATOM   8127  C C   . TYR D 2 15  ? 152.194 191.772 169.930 1.00 17.86  ? 31  TYR E C   1 
ATOM   8128  O O   . TYR D 2 15  ? 153.383 192.105 169.939 1.00 19.40  ? 31  TYR E O   1 
ATOM   8129  C CB  . TYR D 2 15  ? 152.634 189.321 169.760 1.00 15.67  ? 31  TYR E CB  1 
ATOM   8130  C CG  . TYR D 2 15  ? 152.304 187.924 170.224 1.00 20.39  ? 31  TYR E CG  1 
ATOM   8131  C CD1 . TYR D 2 15  ? 152.465 187.560 171.550 1.00 19.90  ? 31  TYR E CD1 1 
ATOM   8132  C CD2 . TYR D 2 15  ? 151.825 186.969 169.338 1.00 24.54  ? 31  TYR E CD2 1 
ATOM   8133  C CE1 . TYR D 2 15  ? 152.160 186.288 171.983 1.00 23.28  ? 31  TYR E CE1 1 
ATOM   8134  C CE2 . TYR D 2 15  ? 151.519 185.691 169.763 1.00 22.76  ? 31  TYR E CE2 1 
ATOM   8135  C CZ  . TYR D 2 15  ? 151.689 185.359 171.087 1.00 24.56  ? 31  TYR E CZ  1 
ATOM   8136  O OH  . TYR D 2 15  ? 151.391 184.092 171.522 1.00 29.24  ? 31  TYR E OH  1 
ATOM   8137  N N   . PHE D 2 16  ? 151.234 192.569 169.468 1.00 22.89  ? 32  PHE E N   1 
ATOM   8138  C CA  . PHE D 2 16  ? 151.510 193.908 168.972 1.00 19.26  ? 32  PHE E CA  1 
ATOM   8139  C C   . PHE D 2 16  ? 150.926 195.006 169.846 1.00 19.13  ? 32  PHE E C   1 
ATOM   8140  O O   . PHE D 2 16  ? 151.233 196.181 169.619 1.00 22.43  ? 32  PHE E O   1 
ATOM   8141  C CB  . PHE D 2 16  ? 150.978 194.066 167.539 1.00 18.07  ? 32  PHE E CB  1 
ATOM   8142  C CG  . PHE D 2 16  ? 151.638 193.158 166.541 1.00 16.74  ? 32  PHE E CG  1 
ATOM   8143  C CD1 . PHE D 2 16  ? 151.217 191.849 166.388 1.00 19.05  ? 32  PHE E CD1 1 
ATOM   8144  C CD2 . PHE D 2 16  ? 152.675 193.616 165.750 1.00 16.08  ? 32  PHE E CD2 1 
ATOM   8145  C CE1 . PHE D 2 16  ? 151.822 191.015 165.473 1.00 18.33  ? 32  PHE E CE1 1 
ATOM   8146  C CE2 . PHE D 2 16  ? 153.281 192.785 164.831 1.00 17.56  ? 32  PHE E CE2 1 
ATOM   8147  C CZ  . PHE D 2 16  ? 152.855 191.485 164.693 1.00 17.81  ? 32  PHE E CZ  1 
ATOM   8148  N N   . VAL D 2 17  ? 150.095 194.666 170.829 1.00 19.50  ? 33  VAL E N   1 
ATOM   8149  C CA  . VAL D 2 17  ? 149.501 195.662 171.713 1.00 22.26  ? 33  VAL E CA  1 
ATOM   8150  C C   . VAL D 2 17  ? 149.843 195.331 173.160 1.00 22.92  ? 33  VAL E C   1 
ATOM   8151  O O   . VAL D 2 17  ? 150.475 196.134 173.854 1.00 28.09  ? 33  VAL E O   1 
ATOM   8152  C CB  . VAL D 2 17  ? 147.979 195.755 171.506 1.00 25.74  ? 33  VAL E CB  1 
ATOM   8153  C CG1 . VAL D 2 17  ? 147.323 196.465 172.676 1.00 24.76  ? 33  VAL E CG1 1 
ATOM   8154  C CG2 . VAL D 2 17  ? 147.667 196.474 170.207 1.00 28.07  ? 33  VAL E CG2 1 
ATOM   8155  N N   . ASN D 2 18  ? 149.434 194.153 173.626 1.00 21.54  ? 34  ASN E N   1 
ATOM   8156  C CA  . ASN D 2 18  ? 149.718 193.750 174.996 1.00 22.79  ? 34  ASN E CA  1 
ATOM   8157  C C   . ASN D 2 18  ? 149.538 192.245 175.132 1.00 25.15  ? 34  ASN E C   1 
ATOM   8158  O O   . ASN D 2 18  ? 148.647 191.661 174.513 1.00 29.86  ? 34  ASN E O   1 
ATOM   8159  C CB  . ASN D 2 18  ? 148.827 194.495 175.999 1.00 28.76  ? 34  ASN E CB  1 
ATOM   8160  C CG  . ASN D 2 18  ? 147.446 193.890 176.128 1.00 33.49  ? 34  ASN E CG  1 
ATOM   8161  O OD1 . ASN D 2 18  ? 146.793 193.574 175.134 1.00 35.66  ? 34  ASN E OD1 1 
ATOM   8162  N ND2 . ASN D 2 18  ? 146.989 193.728 177.363 1.00 36.70  ? 34  ASN E ND2 1 
ATOM   8163  N N   . TYR D 2 19  ? 150.394 191.627 175.941 1.00 24.70  ? 35  TYR E N   1 
ATOM   8164  C CA  . TYR D 2 19  ? 150.364 190.186 176.141 1.00 23.61  ? 35  TYR E CA  1 
ATOM   8165  C C   . TYR D 2 19  ? 151.110 189.857 177.426 1.00 22.10  ? 35  TYR E C   1 
ATOM   8166  O O   . TYR D 2 19  ? 151.718 190.724 178.055 1.00 23.21  ? 35  TYR E O   1 
ATOM   8167  C CB  . TYR D 2 19  ? 150.960 189.439 174.942 1.00 22.99  ? 35  TYR E CB  1 
ATOM   8168  C CG  . TYR D 2 19  ? 152.424 189.721 174.681 1.00 21.66  ? 35  TYR E CG  1 
ATOM   8169  C CD1 . TYR D 2 19  ? 152.824 190.884 174.043 1.00 18.49  ? 35  TYR E CD1 1 
ATOM   8170  C CD2 . TYR D 2 19  ? 153.401 188.813 175.056 1.00 21.68  ? 35  TYR E CD2 1 
ATOM   8171  C CE1 . TYR D 2 19  ? 154.151 191.138 173.800 1.00 16.41  ? 35  TYR E CE1 1 
ATOM   8172  C CE2 . TYR D 2 19  ? 154.731 189.061 174.816 1.00 19.19  ? 35  TYR E CE2 1 
ATOM   8173  C CZ  . TYR D 2 19  ? 155.101 190.223 174.188 1.00 19.61  ? 35  TYR E CZ  1 
ATOM   8174  O OH  . TYR D 2 19  ? 156.430 190.473 173.944 1.00 26.24  ? 35  TYR E OH  1 
ATOM   8175  N N   . THR D 2 20  ? 151.051 188.586 177.809 1.00 23.40  ? 36  THR E N   1 
ATOM   8176  C CA  . THR D 2 20  ? 151.650 188.107 179.046 1.00 24.26  ? 36  THR E CA  1 
ATOM   8177  C C   . THR D 2 20  ? 152.929 187.340 178.736 1.00 27.33  ? 36  THR E C   1 
ATOM   8178  O O   . THR D 2 20  ? 152.909 186.373 177.968 1.00 30.08  ? 36  THR E O   1 
ATOM   8179  C CB  . THR D 2 20  ? 150.673 187.212 179.811 1.00 26.95  ? 36  THR E CB  1 
ATOM   8180  O OG1 . THR D 2 20  ? 149.618 188.011 180.359 1.00 30.83  ? 36  THR E OG1 1 
ATOM   8181  C CG2 . THR D 2 20  ? 151.378 186.488 180.938 1.00 25.45  ? 36  THR E CG2 1 
ATOM   8182  N N   . PHE D 2 21  ? 154.035 187.772 179.338 1.00 26.39  ? 37  PHE E N   1 
ATOM   8183  C CA  . PHE D 2 21  ? 155.329 187.127 179.166 1.00 22.78  ? 37  PHE E CA  1 
ATOM   8184  C C   . PHE D 2 21  ? 155.639 186.301 180.408 1.00 25.44  ? 37  PHE E C   1 
ATOM   8185  O O   . PHE D 2 21  ? 155.645 186.830 181.524 1.00 27.79  ? 37  PHE E O   1 
ATOM   8186  C CB  . PHE D 2 21  ? 156.426 188.162 178.919 1.00 19.53  ? 37  PHE E CB  1 
ATOM   8187  C CG  . PHE D 2 21  ? 157.824 187.620 179.059 1.00 22.44  ? 37  PHE E CG  1 
ATOM   8188  C CD1 . PHE D 2 21  ? 158.258 186.567 178.272 1.00 21.40  ? 37  PHE E CD1 1 
ATOM   8189  C CD2 . PHE D 2 21  ? 158.708 188.174 179.971 1.00 22.54  ? 37  PHE E CD2 1 
ATOM   8190  C CE1 . PHE D 2 21  ? 159.543 186.075 178.399 1.00 21.67  ? 37  PHE E CE1 1 
ATOM   8191  C CE2 . PHE D 2 21  ? 159.993 187.683 180.099 1.00 19.71  ? 37  PHE E CE2 1 
ATOM   8192  C CZ  . PHE D 2 21  ? 160.410 186.634 179.313 1.00 18.51  ? 37  PHE E CZ  1 
ATOM   8193  N N   . LYS D 2 22  ? 155.888 185.011 180.215 1.00 26.79  ? 38  LYS E N   1 
ATOM   8194  C CA  . LYS D 2 22  ? 156.267 184.112 181.294 1.00 28.69  ? 38  LYS E CA  1 
ATOM   8195  C C   . LYS D 2 22  ? 157.662 183.575 181.012 1.00 34.03  ? 38  LYS E C   1 
ATOM   8196  O O   . LYS D 2 22  ? 157.926 183.064 179.919 1.00 37.44  ? 38  LYS E O   1 
ATOM   8197  C CB  . LYS D 2 22  ? 155.261 182.967 181.440 1.00 32.56  ? 38  LYS E CB  1 
ATOM   8198  C CG  . LYS D 2 22  ? 155.876 181.629 181.806 1.00 40.49  ? 38  LYS E CG  1 
ATOM   8199  C CD  . LYS D 2 22  ? 154.841 180.685 182.385 1.00 48.55  ? 38  LYS E CD  1 
ATOM   8200  C CE  . LYS D 2 22  ? 155.473 179.369 182.806 1.00 53.22  ? 38  LYS E CE  1 
ATOM   8201  N NZ  . LYS D 2 22  ? 154.512 178.495 183.533 1.00 50.63  ? 38  LYS E NZ  1 
ATOM   8202  N N   . ASP D 2 23  ? 158.552 183.704 181.990 1.00 30.01  ? 39  ASP E N   1 
ATOM   8203  C CA  . ASP D 2 23  ? 159.927 183.244 181.851 1.00 29.40  ? 39  ASP E CA  1 
ATOM   8204  C C   . ASP D 2 23  ? 160.014 181.792 182.301 1.00 37.66  ? 39  ASP E C   1 
ATOM   8205  O O   . ASP D 2 23  ? 159.749 181.480 183.467 1.00 42.09  ? 39  ASP E O   1 
ATOM   8206  C CB  . ASP D 2 23  ? 160.873 184.120 182.670 1.00 28.82  ? 39  ASP E CB  1 
ATOM   8207  C CG  . ASP D 2 23  ? 162.262 184.187 182.078 1.00 30.83  ? 39  ASP E CG  1 
ATOM   8208  O OD1 . ASP D 2 23  ? 162.511 183.511 181.061 1.00 34.09  ? 39  ASP E OD1 1 
ATOM   8209  O OD2 . ASP D 2 23  ? 163.108 184.917 182.631 1.00 29.28  ? 39  ASP E OD2 1 
ATOM   8210  N N   . ARG D 2 24  ? 160.384 180.906 181.377 1.00 38.38  ? 40  ARG E N   1 
ATOM   8211  C CA  . ARG D 2 24  ? 160.496 179.490 181.693 1.00 37.98  ? 40  ARG E CA  1 
ATOM   8212  C C   . ARG D 2 24  ? 161.808 179.137 182.378 1.00 37.40  ? 40  ARG E C   1 
ATOM   8213  O O   . ARG D 2 24  ? 161.951 178.011 182.865 1.00 43.98  ? 40  ARG E O   1 
ATOM   8214  C CB  . ARG D 2 24  ? 160.333 178.655 180.422 1.00 43.75  ? 40  ARG E CB  1 
ATOM   8215  C CG  . ARG D 2 24  ? 158.902 178.212 180.160 1.00 47.70  ? 40  ARG E CG  1 
ATOM   8216  C CD  . ARG D 2 24  ? 158.583 178.209 178.674 1.00 54.67  ? 40  ARG E CD  1 
ATOM   8217  N NE  . ARG D 2 24  ? 157.247 178.725 178.399 1.00 55.29  ? 40  ARG E NE  1 
ATOM   8218  C CZ  . ARG D 2 24  ? 156.980 179.984 178.080 1.00 49.99  ? 40  ARG E CZ  1 
ATOM   8219  N NH1 . ARG D 2 24  ? 157.938 180.891 177.985 1.00 44.09  ? 40  ARG E NH1 1 
ATOM   8220  N NH2 . ARG D 2 24  ? 155.720 180.342 177.849 1.00 43.56  ? 40  ARG E NH2 1 
ATOM   8221  N N   . SER D 2 25  ? 162.761 180.064 182.433 1.00 33.11  ? 41  SER E N   1 
ATOM   8222  C CA  . SER D 2 25  ? 164.026 179.855 183.119 1.00 35.34  ? 41  SER E CA  1 
ATOM   8223  C C   . SER D 2 25  ? 164.072 180.533 184.482 1.00 36.64  ? 41  SER E C   1 
ATOM   8224  O O   . SER D 2 25  ? 165.150 180.642 185.072 1.00 34.32  ? 41  SER E O   1 
ATOM   8225  C CB  . SER D 2 25  ? 165.182 180.349 182.249 1.00 32.25  ? 41  SER E CB  1 
ATOM   8226  O OG  . SER D 2 25  ? 165.100 181.747 182.040 1.00 31.05  ? 41  SER E OG  1 
ATOM   8227  N N   . HIS D 2 26  ? 162.927 180.990 184.992 1.00 36.10  ? 42  HIS E N   1 
ATOM   8228  C CA  . HIS D 2 26  ? 162.909 181.730 186.249 1.00 30.01  ? 42  HIS E CA  1 
ATOM   8229  C C   . HIS D 2 26  ? 163.252 180.833 187.432 1.00 32.21  ? 42  HIS E C   1 
ATOM   8230  O O   . HIS D 2 26  ? 164.073 181.198 188.281 1.00 32.43  ? 42  HIS E O   1 
ATOM   8231  C CB  . HIS D 2 26  ? 161.540 182.383 186.444 1.00 31.63  ? 42  HIS E CB  1 
ATOM   8232  C CG  . HIS D 2 26  ? 161.223 182.715 187.869 1.00 33.40  ? 42  HIS E CG  1 
ATOM   8233  N ND1 . HIS D 2 26  ? 161.728 183.828 188.505 1.00 31.13  ? 42  HIS E ND1 1 
ATOM   8234  C CD2 . HIS D 2 26  ? 160.446 182.082 188.780 1.00 29.18  ? 42  HIS E CD2 1 
ATOM   8235  C CE1 . HIS D 2 26  ? 161.281 183.864 189.747 1.00 28.68  ? 42  HIS E CE1 1 
ATOM   8236  N NE2 . HIS D 2 26  ? 160.501 182.817 189.940 1.00 30.18  ? 42  HIS E NE2 1 
ATOM   8237  N N   . SER D 2 27  ? 162.627 179.655 187.508 1.00 33.51  ? 43  SER E N   1 
ATOM   8238  C CA  . SER D 2 27  ? 162.805 178.789 188.671 1.00 30.33  ? 43  SER E CA  1 
ATOM   8239  C C   . SER D 2 27  ? 164.228 178.254 188.764 1.00 32.94  ? 43  SER E C   1 
ATOM   8240  O O   . SER D 2 27  ? 164.816 178.225 189.852 1.00 34.39  ? 43  SER E O   1 
ATOM   8241  C CB  . SER D 2 27  ? 161.800 177.641 188.621 1.00 32.31  ? 43  SER E CB  1 
ATOM   8242  O OG  . SER D 2 27  ? 161.782 177.038 187.341 1.00 40.63  ? 43  SER E OG  1 
ATOM   8243  N N   . GLY D 2 28  ? 164.797 177.820 187.638 1.00 34.59  ? 44  GLY E N   1 
ATOM   8244  C CA  . GLY D 2 28  ? 166.169 177.340 187.655 1.00 35.25  ? 44  GLY E CA  1 
ATOM   8245  C C   . GLY D 2 28  ? 167.160 178.425 188.026 1.00 36.29  ? 44  GLY E C   1 
ATOM   8246  O O   . GLY D 2 28  ? 168.105 178.185 188.781 1.00 42.10  ? 44  GLY E O   1 
ATOM   8247  N N   . ARG D 2 29  ? 166.958 179.634 187.498 1.00 35.88  ? 45  ARG E N   1 
ATOM   8248  C CA  . ARG D 2 29  ? 167.827 180.755 187.842 1.00 35.18  ? 45  ARG E CA  1 
ATOM   8249  C C   . ARG D 2 29  ? 167.717 181.105 189.320 1.00 33.21  ? 45  ARG E C   1 
ATOM   8250  O O   . ARG D 2 29  ? 168.729 181.378 189.976 1.00 32.83  ? 45  ARG E O   1 
ATOM   8251  C CB  . ARG D 2 29  ? 167.481 181.962 186.971 1.00 34.53  ? 45  ARG E CB  1 
ATOM   8252  C CG  . ARG D 2 29  ? 168.163 183.254 187.375 1.00 34.97  ? 45  ARG E CG  1 
ATOM   8253  C CD  . ARG D 2 29  ? 167.968 184.324 186.315 1.00 30.63  ? 45  ARG E CD  1 
ATOM   8254  N NE  . ARG D 2 29  ? 166.566 184.696 186.172 1.00 33.84  ? 45  ARG E NE  1 
ATOM   8255  C CZ  . ARG D 2 29  ? 165.829 184.448 185.098 1.00 32.37  ? 45  ARG E CZ  1 
ATOM   8256  N NH1 . ARG D 2 29  ? 166.334 183.838 184.040 1.00 29.00  ? 45  ARG E NH1 1 
ATOM   8257  N NH2 . ARG D 2 29  ? 164.554 184.822 185.087 1.00 29.80  ? 45  ARG E NH2 1 
ATOM   8258  N N   . VAL D 2 30  ? 166.497 181.092 189.863 1.00 33.78  ? 46  VAL E N   1 
ATOM   8259  C CA  . VAL D 2 30  ? 166.302 181.368 191.284 1.00 34.84  ? 46  VAL E CA  1 
ATOM   8260  C C   . VAL D 2 30  ? 167.010 180.319 192.132 1.00 39.33  ? 46  VAL E C   1 
ATOM   8261  O O   . VAL D 2 30  ? 167.693 180.644 193.110 1.00 41.79  ? 46  VAL E O   1 
ATOM   8262  C CB  . VAL D 2 30  ? 164.799 181.440 191.615 1.00 33.60  ? 46  VAL E CB  1 
ATOM   8263  C CG1 . VAL D 2 30  ? 164.538 181.012 193.051 1.00 32.17  ? 46  VAL E CG1 1 
ATOM   8264  C CG2 . VAL D 2 30  ? 164.275 182.840 191.383 1.00 37.67  ? 46  VAL E CG2 1 
ATOM   8265  N N   . ALA D 2 31  ? 166.863 179.043 191.766 1.00 38.75  ? 47  ALA E N   1 
ATOM   8266  C CA  . ALA D 2 31  ? 167.495 177.974 192.533 1.00 35.96  ? 47  ALA E CA  1 
ATOM   8267  C C   . ALA D 2 31  ? 169.015 178.080 192.484 1.00 38.17  ? 47  ALA E C   1 
ATOM   8268  O O   . ALA D 2 31  ? 169.692 177.951 193.511 1.00 40.89  ? 47  ALA E O   1 
ATOM   8269  C CB  . ALA D 2 31  ? 167.032 176.615 192.013 1.00 37.96  ? 47  ALA E CB  1 
ATOM   8270  N N   . GLN D 2 32  ? 169.570 178.321 191.293 1.00 38.02  ? 48  GLN E N   1 
ATOM   8271  C CA  . GLN D 2 32  ? 171.018 178.443 191.161 1.00 38.71  ? 48  GLN E CA  1 
ATOM   8272  C C   . GLN D 2 32  ? 171.546 179.640 191.940 1.00 43.07  ? 48  GLN E C   1 
ATOM   8273  O O   . GLN D 2 32  ? 172.590 179.550 192.600 1.00 48.68  ? 48  GLN E O   1 
ATOM   8274  C CB  . GLN D 2 32  ? 171.401 178.548 189.686 1.00 40.78  ? 48  GLN E CB  1 
ATOM   8275  C CG  . GLN D 2 32  ? 172.208 177.371 189.167 1.00 47.53  ? 48  GLN E CG  1 
ATOM   8276  C CD  . GLN D 2 32  ? 171.428 176.072 189.184 1.00 52.77  ? 48  GLN E CD  1 
ATOM   8277  O OE1 . GLN D 2 32  ? 170.357 175.969 188.587 1.00 52.72  ? 48  GLN E OE1 1 
ATOM   8278  N NE2 . GLN D 2 32  ? 171.965 175.069 189.869 1.00 49.99  ? 48  GLN E NE2 1 
ATOM   8279  N N   . GLY D 2 33  ? 170.842 180.772 191.877 1.00 42.50  ? 49  GLY E N   1 
ATOM   8280  C CA  . GLY D 2 33  ? 171.264 181.934 192.639 1.00 41.21  ? 49  GLY E CA  1 
ATOM   8281  C C   . GLY D 2 33  ? 171.192 181.705 194.134 1.00 42.56  ? 49  GLY E C   1 
ATOM   8282  O O   . GLY D 2 33  ? 172.063 182.154 194.881 1.00 47.81  ? 49  GLY E O   1 
ATOM   8283  N N   . ILE D 2 34  ? 170.151 181.008 194.593 1.00 41.07  ? 50  ILE E N   1 
ATOM   8284  C CA  . ILE D 2 34  ? 170.038 180.693 196.015 1.00 45.27  ? 50  ILE E CA  1 
ATOM   8285  C C   . ILE D 2 34  ? 171.205 179.817 196.451 1.00 50.43  ? 50  ILE E C   1 
ATOM   8286  O O   . ILE D 2 34  ? 171.847 180.078 197.474 1.00 54.55  ? 50  ILE E O   1 
ATOM   8287  C CB  . ILE D 2 34  ? 168.678 180.033 196.318 1.00 42.35  ? 50  ILE E CB  1 
ATOM   8288  C CG1 . ILE D 2 34  ? 167.651 181.071 196.783 1.00 45.27  ? 50  ILE E CG1 1 
ATOM   8289  C CG2 . ILE D 2 34  ? 168.817 178.952 197.382 1.00 38.44  ? 50  ILE E CG2 1 
ATOM   8290  C CD1 . ILE D 2 34  ? 167.573 182.322 195.936 1.00 44.83  ? 50  ILE E CD1 1 
ATOM   8291  N N   . MET D 2 35  ? 171.520 178.784 195.663 1.00 48.19  ? 51  MET E N   1 
ATOM   8292  C CA  . MET D 2 35  ? 172.650 177.922 196.001 1.00 46.02  ? 51  MET E CA  1 
ATOM   8293  C C   . MET D 2 35  ? 173.943 178.725 196.081 1.00 54.10  ? 51  MET E C   1 
ATOM   8294  O O   . MET D 2 35  ? 174.668 178.662 197.084 1.00 57.50  ? 51  MET E O   1 
ATOM   8295  C CB  . MET D 2 35  ? 172.785 176.792 194.979 1.00 43.26  ? 51  MET E CB  1 
ATOM   8296  C CG  . MET D 2 35  ? 171.581 175.873 194.896 1.00 44.58  ? 51  MET E CG  1 
ATOM   8297  S SD  . MET D 2 35  ? 171.635 174.725 193.506 1.00 49.21  ? 51  MET E SD  1 
ATOM   8298  C CE  . MET D 2 35  ? 173.385 174.722 193.136 1.00 51.69  ? 51  MET E CE  1 
ATOM   8299  N N   . LYS D 2 36  ? 174.233 179.508 195.040 1.00 56.83  ? 52  LYS E N   1 
ATOM   8300  C CA  . LYS D 2 36  ? 175.452 180.309 195.023 1.00 56.50  ? 52  LYS E CA  1 
ATOM   8301  C C   . LYS D 2 36  ? 175.524 181.220 196.241 1.00 56.88  ? 52  LYS E C   1 
ATOM   8302  O O   . LYS D 2 36  ? 176.425 181.089 197.075 1.00 63.82  ? 52  LYS E O   1 
ATOM   8303  C CB  . LYS D 2 36  ? 175.525 181.124 193.732 1.00 55.01  ? 52  LYS E CB  1 
ATOM   8304  C CG  . LYS D 2 36  ? 176.141 180.380 192.559 1.00 62.12  ? 52  LYS E CG  1 
ATOM   8305  C CD  . LYS D 2 36  ? 175.720 180.977 191.221 1.00 63.20  ? 52  LYS E CD  1 
ATOM   8306  C CE  . LYS D 2 36  ? 175.664 182.500 191.254 1.00 64.78  ? 52  LYS E CE  1 
ATOM   8307  N NZ  . LYS D 2 36  ? 176.951 183.117 191.687 1.00 66.70  ? 52  LYS E NZ  1 
ATOM   8308  N N   . LEU D 2 37  ? 174.543 182.114 196.386 1.00 54.65  ? 53  LEU E N   1 
ATOM   8309  C CA  . LEU D 2 37  ? 174.589 183.115 197.446 1.00 60.01  ? 53  LEU E CA  1 
ATOM   8310  C C   . LEU D 2 37  ? 174.658 182.475 198.826 1.00 62.00  ? 53  LEU E C   1 
ATOM   8311  O O   . LEU D 2 37  ? 175.409 182.937 199.692 1.00 65.20  ? 53  LEU E O   1 
ATOM   8312  C CB  . LEU D 2 37  ? 173.367 184.026 197.349 1.00 60.09  ? 53  LEU E CB  1 
ATOM   8313  C CG  . LEU D 2 37  ? 173.260 184.950 196.138 1.00 51.31  ? 53  LEU E CG  1 
ATOM   8314  C CD1 . LEU D 2 37  ? 172.063 185.856 196.303 1.00 46.10  ? 53  LEU E CD1 1 
ATOM   8315  C CD2 . LEU D 2 37  ? 174.528 185.763 195.961 1.00 52.25  ? 53  LEU E CD2 1 
ATOM   8316  N N   . CYS D 2 38  ? 173.884 181.413 199.057 1.00 58.12  ? 54  CYS E N   1 
ATOM   8317  C CA  . CYS D 2 38  ? 173.798 180.850 200.395 1.00 58.50  ? 54  CYS E CA  1 
ATOM   8318  C C   . CYS D 2 38  ? 175.021 180.024 200.771 1.00 62.64  ? 54  CYS E C   1 
ATOM   8319  O O   . CYS D 2 38  ? 175.431 180.046 201.937 1.00 63.32  ? 54  CYS E O   1 
ATOM   8320  C CB  . CYS D 2 38  ? 172.532 180.003 200.519 1.00 56.72  ? 54  CYS E CB  1 
ATOM   8321  S SG  . CYS D 2 38  ? 170.996 180.938 200.330 1.00 60.24  ? 54  CYS E SG  1 
ATOM   8322  N N   . LEU D 2 39  ? 175.626 179.296 199.832 1.00 63.96  ? 55  LEU E N   1 
ATOM   8323  C CA  . LEU D 2 39  ? 176.719 178.403 200.194 1.00 65.75  ? 55  LEU E CA  1 
ATOM   8324  C C   . LEU D 2 39  ? 178.090 178.898 199.758 1.00 68.19  ? 55  LEU E C   1 
ATOM   8325  O O   . LEU D 2 39  ? 179.031 178.866 200.557 1.00 70.72  ? 55  LEU E O   1 
ATOM   8326  C CB  . LEU D 2 39  ? 176.468 176.992 199.636 1.00 62.29  ? 55  LEU E CB  1 
ATOM   8327  C CG  . LEU D 2 39  ? 175.202 176.251 200.093 1.00 58.69  ? 55  LEU E CG  1 
ATOM   8328  C CD1 . LEU D 2 39  ? 175.014 176.370 201.603 1.00 56.25  ? 55  LEU E CD1 1 
ATOM   8329  C CD2 . LEU D 2 39  ? 173.940 176.669 199.350 1.00 54.02  ? 55  LEU E CD2 1 
ATOM   8330  N N   . GLU D 2 40  ? 178.246 179.349 198.512 1.00 68.78  ? 56  GLU E N   1 
ATOM   8331  C CA  . GLU D 2 40  ? 179.572 179.745 198.055 1.00 72.57  ? 56  GLU E CA  1 
ATOM   8332  C C   . GLU D 2 40  ? 180.039 181.034 198.717 1.00 73.97  ? 56  GLU E C   1 
ATOM   8333  O O   . GLU D 2 40  ? 181.245 181.224 198.912 1.00 76.85  ? 56  GLU E O   1 
ATOM   8334  C CB  . GLU D 2 40  ? 179.576 179.896 196.534 1.00 72.45  ? 56  GLU E CB  1 
ATOM   8335  C CG  . GLU D 2 40  ? 180.009 178.648 195.777 1.00 73.18  ? 56  GLU E CG  1 
ATOM   8336  C CD  . GLU D 2 40  ? 178.889 177.638 195.603 1.00 77.06  ? 56  GLU E CD  1 
ATOM   8337  O OE1 . GLU D 2 40  ? 177.980 177.588 196.458 1.00 74.87  ? 56  GLU E OE1 1 
ATOM   8338  O OE2 . GLU D 2 40  ? 178.914 176.892 194.602 1.00 80.66  ? 56  GLU E OE2 1 
ATOM   8339  N N   . GLU D 2 41  ? 179.115 181.926 199.069 1.00 70.84  ? 57  GLU E N   1 
ATOM   8340  C CA  . GLU D 2 41  ? 179.474 183.224 199.622 1.00 71.28  ? 57  GLU E CA  1 
ATOM   8341  C C   . GLU D 2 41  ? 178.880 183.507 200.995 1.00 69.99  ? 57  GLU E C   1 
ATOM   8342  O O   . GLU D 2 41  ? 179.418 184.355 201.710 1.00 69.80  ? 57  GLU E O   1 
ATOM   8343  C CB  . GLU D 2 41  ? 179.066 184.344 198.651 1.00 71.44  ? 57  GLU E CB  1 
ATOM   8344  C CG  . GLU D 2 41  ? 178.931 183.880 197.206 1.00 73.87  ? 57  GLU E CG  1 
ATOM   8345  C CD  . GLU D 2 41  ? 178.477 184.981 196.269 1.00 82.20  ? 57  GLU E CD  1 
ATOM   8346  O OE1 . GLU D 2 41  ? 178.084 184.665 195.126 1.00 80.93  ? 57  GLU E OE1 1 
ATOM   8347  O OE2 . GLU D 2 41  ? 178.528 186.163 196.666 1.00 83.37  ? 57  GLU E OE2 1 
ATOM   8348  N N   . GLU D 2 42  ? 177.800 182.824 201.384 1.00 68.77  ? 58  GLU E N   1 
ATOM   8349  C CA  . GLU D 2 42  ? 177.218 182.922 202.726 1.00 69.19  ? 58  GLU E CA  1 
ATOM   8350  C C   . GLU D 2 42  ? 176.824 184.377 203.024 1.00 66.76  ? 58  GLU E C   1 
ATOM   8351  O O   . GLU D 2 42  ? 177.464 185.108 203.783 1.00 66.14  ? 58  GLU E O   1 
ATOM   8352  C CB  . GLU D 2 42  ? 178.182 182.305 203.762 1.00 71.94  ? 58  GLU E CB  1 
ATOM   8353  C CG  . GLU D 2 42  ? 178.194 182.790 205.239 1.00 74.30  ? 58  GLU E CG  1 
ATOM   8354  C CD  . GLU D 2 42  ? 176.817 183.050 205.855 1.00 70.59  ? 58  GLU E CD  1 
ATOM   8355  O OE1 . GLU D 2 42  ? 175.798 182.536 205.345 1.00 64.77  ? 58  GLU E OE1 1 
ATOM   8356  O OE2 . GLU D 2 42  ? 176.758 183.784 206.864 1.00 70.06  ? 58  GLU E OE2 1 
ATOM   8357  N N   . LEU D 2 43  ? 175.791 184.813 202.309 1.00 62.41  ? 59  LEU E N   1 
ATOM   8358  C CA  . LEU D 2 43  ? 175.268 186.162 202.446 1.00 55.17  ? 59  LEU E CA  1 
ATOM   8359  C C   . LEU D 2 43  ? 173.830 186.138 202.947 1.00 53.51  ? 59  LEU E C   1 
ATOM   8360  O O   . LEU D 2 43  ? 173.083 185.182 202.721 1.00 55.58  ? 59  LEU E O   1 
ATOM   8361  C CB  . LEU D 2 43  ? 175.332 186.921 201.116 1.00 57.18  ? 59  LEU E CB  1 
ATOM   8362  C CG  . LEU D 2 43  ? 176.699 187.088 200.460 1.00 60.24  ? 59  LEU E CG  1 
ATOM   8363  C CD1 . LEU D 2 43  ? 176.547 187.090 198.956 1.00 60.70  ? 59  LEU E CD1 1 
ATOM   8364  C CD2 . LEU D 2 43  ? 177.364 188.368 200.933 1.00 61.59  ? 59  LEU E CD2 1 
ATOM   8365  N N   . PHE D 2 44  ? 173.459 187.215 203.642 1.00 48.04  ? 60  PHE E N   1 
ATOM   8366  C CA  . PHE D 2 44  ? 172.075 187.494 204.032 1.00 45.48  ? 60  PHE E CA  1 
ATOM   8367  C C   . PHE D 2 44  ? 171.506 186.438 204.977 1.00 46.65  ? 60  PHE E C   1 
ATOM   8368  O O   . PHE D 2 44  ? 170.303 186.171 204.967 1.00 44.52  ? 60  PHE E O   1 
ATOM   8369  C CB  . PHE D 2 44  ? 171.168 187.641 202.803 1.00 46.29  ? 60  PHE E CB  1 
ATOM   8370  C CG  . PHE D 2 44  ? 171.788 188.420 201.676 1.00 47.38  ? 60  PHE E CG  1 
ATOM   8371  C CD1 . PHE D 2 44  ? 172.425 189.625 201.911 1.00 48.35  ? 60  PHE E CD1 1 
ATOM   8372  C CD2 . PHE D 2 44  ? 171.728 187.945 200.378 1.00 44.47  ? 60  PHE E CD2 1 
ATOM   8373  C CE1 . PHE D 2 44  ? 172.994 190.337 200.875 1.00 48.68  ? 60  PHE E CE1 1 
ATOM   8374  C CE2 . PHE D 2 44  ? 172.294 188.654 199.340 1.00 44.05  ? 60  PHE E CE2 1 
ATOM   8375  C CZ  . PHE D 2 44  ? 172.927 189.851 199.589 1.00 46.09  ? 60  PHE E CZ  1 
ATOM   8376  N N   . ALA D 2 45  ? 172.353 185.835 205.808 1.00 49.84  ? 61  ALA E N   1 
ATOM   8377  C CA  . ALA D 2 45  ? 171.867 184.893 206.808 1.00 45.09  ? 61  ALA E CA  1 
ATOM   8378  C C   . ALA D 2 45  ? 171.146 185.644 207.919 1.00 48.68  ? 61  ALA E C   1 
ATOM   8379  O O   . ALA D 2 45  ? 171.646 186.655 208.422 1.00 55.47  ? 61  ALA E O   1 
ATOM   8380  C CB  . ALA D 2 45  ? 173.024 184.079 207.380 1.00 46.03  ? 61  ALA E CB  1 
ATOM   8381  N N   . ASP D 2 46  ? 169.968 185.152 208.305 1.00 43.97  ? 62  ASP E N   1 
ATOM   8382  C CA  . ASP D 2 46  ? 169.139 185.848 209.277 1.00 42.87  ? 62  ASP E CA  1 
ATOM   8383  C C   . ASP D 2 46  ? 168.707 184.993 210.460 1.00 47.55  ? 62  ASP E C   1 
ATOM   8384  O O   . ASP D 2 46  ? 167.992 185.498 211.332 1.00 52.11  ? 62  ASP E O   1 
ATOM   8385  C CB  . ASP D 2 46  ? 167.889 186.426 208.596 1.00 46.96  ? 62  ASP E CB  1 
ATOM   8386  C CG  . ASP D 2 46  ? 167.275 185.471 207.597 1.00 48.20  ? 62  ASP E CG  1 
ATOM   8387  O OD1 . ASP D 2 46  ? 166.888 184.359 208.002 1.00 48.17  ? 62  ASP E OD1 1 
ATOM   8388  O OD2 . ASP D 2 46  ? 167.171 185.830 206.405 1.00 48.75  ? 62  ASP E OD2 1 
ATOM   8389  N N   . VAL D 2 47  ? 169.110 183.723 210.520 1.00 51.35  ? 63  VAL E N   1 
ATOM   8390  C CA  . VAL D 2 47  ? 168.788 182.852 211.643 1.00 49.66  ? 63  VAL E CA  1 
ATOM   8391  C C   . VAL D 2 47  ? 169.997 181.979 211.949 1.00 49.51  ? 63  VAL E C   1 
ATOM   8392  O O   . VAL D 2 47  ? 170.863 181.755 211.101 1.00 51.85  ? 63  VAL E O   1 
ATOM   8393  C CB  . VAL D 2 47  ? 167.540 181.981 211.368 1.00 44.60  ? 63  VAL E CB  1 
ATOM   8394  C CG1 . VAL D 2 47  ? 167.922 180.703 210.645 1.00 44.39  ? 63  VAL E CG1 1 
ATOM   8395  C CG2 . VAL D 2 47  ? 166.811 181.675 212.665 1.00 46.82  ? 63  VAL E CG2 1 
ATOM   8396  N N   . THR D 2 48  ? 170.056 181.498 213.188 1.00 52.69  ? 64  THR E N   1 
ATOM   8397  C CA  . THR D 2 48  ? 171.120 180.608 213.634 1.00 56.82  ? 64  THR E CA  1 
ATOM   8398  C C   . THR D 2 48  ? 170.497 179.377 214.272 1.00 60.49  ? 64  THR E C   1 
ATOM   8399  O O   . THR D 2 48  ? 169.635 179.497 215.147 1.00 64.92  ? 64  THR E O   1 
ATOM   8400  C CB  . THR D 2 48  ? 172.058 181.305 214.627 1.00 60.90  ? 64  THR E CB  1 
ATOM   8401  O OG1 . THR D 2 48  ? 172.948 182.174 213.916 1.00 60.38  ? 64  THR E OG1 1 
ATOM   8402  C CG2 . THR D 2 48  ? 172.881 180.284 215.392 1.00 62.41  ? 64  THR E CG2 1 
ATOM   8403  N N   . ILE D 2 49  ? 170.930 178.199 213.830 1.00 61.08  ? 65  ILE E N   1 
ATOM   8404  C CA  . ILE D 2 49  ? 170.461 176.925 214.358 1.00 62.47  ? 65  ILE E CA  1 
ATOM   8405  C C   . ILE D 2 49  ? 171.640 176.222 215.013 1.00 67.08  ? 65  ILE E C   1 
ATOM   8406  O O   . ILE D 2 49  ? 172.704 176.086 214.399 1.00 66.96  ? 65  ILE E O   1 
ATOM   8407  C CB  . ILE D 2 49  ? 169.843 176.046 213.257 1.00 57.12  ? 65  ILE E CB  1 
ATOM   8408  C CG1 . ILE D 2 49  ? 168.703 176.785 212.554 1.00 52.49  ? 65  ILE E CG1 1 
ATOM   8409  C CG2 . ILE D 2 49  ? 169.359 174.730 213.839 1.00 58.17  ? 65  ILE E CG2 1 
ATOM   8410  C CD1 . ILE D 2 49  ? 167.432 176.863 213.360 1.00 55.54  ? 65  ILE E CD1 1 
ATOM   8411  N N   . SER D 2 50  ? 171.453 175.781 216.253 1.00 68.43  ? 66  SER E N   1 
ATOM   8412  C CA  . SER D 2 50  ? 172.497 175.107 217.015 1.00 67.91  ? 66  SER E CA  1 
ATOM   8413  C C   . SER D 2 50  ? 172.121 173.642 217.187 1.00 72.34  ? 66  SER E C   1 
ATOM   8414  O O   . SER D 2 50  ? 171.061 173.330 217.739 1.00 74.49  ? 66  SER E O   1 
ATOM   8415  C CB  . SER D 2 50  ? 172.696 175.771 218.376 1.00 71.63  ? 66  SER E CB  1 
ATOM   8416  O OG  . SER D 2 50  ? 173.567 175.009 219.192 1.00 76.24  ? 66  SER E OG  1 
ATOM   8417  N N   . VAL D 2 51  ? 172.988 172.750 216.714 1.00 71.19  ? 67  VAL E N   1 
ATOM   8418  C CA  . VAL D 2 51  ? 172.793 171.309 216.837 1.00 71.29  ? 67  VAL E CA  1 
ATOM   8419  C C   . VAL D 2 51  ? 174.068 170.723 217.426 1.00 74.72  ? 67  VAL E C   1 
ATOM   8420  O O   . VAL D 2 51  ? 175.122 170.744 216.777 1.00 75.24  ? 67  VAL E O   1 
ATOM   8421  C CB  . VAL D 2 51  ? 172.457 170.649 215.492 1.00 64.76  ? 67  VAL E CB  1 
ATOM   8422  C CG1 . VAL D 2 51  ? 172.491 169.140 215.625 1.00 65.31  ? 67  VAL E CG1 1 
ATOM   8423  C CG2 . VAL D 2 51  ? 171.097 171.108 215.003 1.00 62.58  ? 67  VAL E CG2 1 
ATOM   8424  N N   . GLU D 2 52  ? 173.974 170.201 218.650 1.00 75.02  ? 68  GLU E N   1 
ATOM   8425  C CA  . GLU D 2 52  ? 175.104 169.574 219.338 1.00 78.23  ? 68  GLU E CA  1 
ATOM   8426  C C   . GLU D 2 52  ? 176.304 170.515 219.416 1.00 81.36  ? 68  GLU E C   1 
ATOM   8427  O O   . GLU D 2 52  ? 177.453 170.110 219.230 1.00 81.74  ? 68  GLU E O   1 
ATOM   8428  C CB  . GLU D 2 52  ? 175.488 168.253 218.668 1.00 77.52  ? 68  GLU E CB  1 
ATOM   8429  C CG  . GLU D 2 52  ? 174.448 167.155 218.816 1.00 77.71  ? 68  GLU E CG  1 
ATOM   8430  C CD  . GLU D 2 52  ? 174.952 165.808 218.336 1.00 80.46  ? 68  GLU E CD  1 
ATOM   8431  O OE1 . GLU D 2 52  ? 175.896 165.781 217.520 1.00 79.55  ? 68  GLU E OE1 1 
ATOM   8432  O OE2 . GLU D 2 52  ? 174.402 164.776 218.775 1.00 80.10  ? 68  GLU E OE2 1 
ATOM   8433  N N   . GLY D 2 53  ? 176.034 171.788 219.694 1.00 78.36  ? 69  GLY E N   1 
ATOM   8434  C CA  . GLY D 2 53  ? 177.088 172.772 219.826 1.00 77.68  ? 69  GLY E CA  1 
ATOM   8435  C C   . GLY D 2 53  ? 177.638 173.314 218.527 1.00 80.01  ? 69  GLY E C   1 
ATOM   8436  O O   . GLY D 2 53  ? 178.622 174.062 218.556 1.00 80.69  ? 69  GLY E O   1 
ATOM   8437  N N   . ARG D 2 54  ? 177.042 172.964 217.391 1.00 78.77  ? 70  ARG E N   1 
ATOM   8438  C CA  . ARG D 2 54  ? 177.470 173.461 216.091 1.00 73.34  ? 70  ARG E CA  1 
ATOM   8439  C C   . ARG D 2 54  ? 176.475 174.506 215.605 1.00 73.57  ? 70  ARG E C   1 
ATOM   8440  O O   . ARG D 2 54  ? 175.264 174.266 215.613 1.00 73.39  ? 70  ARG E O   1 
ATOM   8441  C CB  . ARG D 2 54  ? 177.581 172.319 215.081 1.00 70.03  ? 70  ARG E CB  1 
ATOM   8442  C CG  . ARG D 2 54  ? 177.529 172.760 213.631 1.00 67.25  ? 70  ARG E CG  1 
ATOM   8443  C CD  . ARG D 2 54  ? 178.920 173.000 213.073 1.00 69.37  ? 70  ARG E CD  1 
ATOM   8444  N NE  . ARG D 2 54  ? 178.937 172.949 211.616 1.00 70.88  ? 70  ARG E NE  1 
ATOM   8445  C CZ  . ARG D 2 54  ? 178.931 171.829 210.905 1.00 71.00  ? 70  ARG E CZ  1 
ATOM   8446  N NH1 . ARG D 2 54  ? 178.915 170.641 211.486 1.00 71.03  ? 70  ARG E NH1 1 
ATOM   8447  N NH2 . ARG D 2 54  ? 178.943 171.904 209.577 1.00 65.02  ? 70  ARG E NH2 1 
ATOM   8448  N N   . GLU D 2 55  ? 176.987 175.658 215.181 1.00 72.67  ? 71  GLU E N   1 
ATOM   8449  C CA  . GLU D 2 55  ? 176.157 176.786 214.780 1.00 69.10  ? 71  GLU E CA  1 
ATOM   8450  C C   . GLU D 2 55  ? 175.975 176.787 213.269 1.00 66.86  ? 71  GLU E C   1 
ATOM   8451  O O   . GLU D 2 55  ? 176.956 176.717 212.520 1.00 64.46  ? 71  GLU E O   1 
ATOM   8452  C CB  . GLU D 2 55  ? 176.781 178.105 215.236 1.00 70.00  ? 71  GLU E CB  1 
ATOM   8453  C CG  . GLU D 2 55  ? 177.189 178.125 216.696 1.00 74.65  ? 71  GLU E CG  1 
ATOM   8454  C CD  . GLU D 2 55  ? 176.350 179.076 217.521 1.00 79.46  ? 71  GLU E CD  1 
ATOM   8455  O OE1 . GLU D 2 55  ? 176.917 180.034 218.086 1.00 83.79  ? 71  GLU E OE1 1 
ATOM   8456  O OE2 . GLU D 2 55  ? 175.122 178.865 217.607 1.00 77.32  ? 71  GLU E OE2 1 
ATOM   8457  N N   . PHE D 2 56  ? 174.723 176.874 212.828 1.00 62.13  ? 72  PHE E N   1 
ATOM   8458  C CA  . PHE D 2 56  ? 174.377 176.911 211.414 1.00 56.47  ? 72  PHE E CA  1 
ATOM   8459  C C   . PHE D 2 56  ? 173.801 178.278 211.080 1.00 55.62  ? 72  PHE E C   1 
ATOM   8460  O O   . PHE D 2 56  ? 172.843 178.722 211.719 1.00 57.57  ? 72  PHE E O   1 
ATOM   8461  C CB  . PHE D 2 56  ? 173.367 175.816 211.064 1.00 57.09  ? 72  PHE E CB  1 
ATOM   8462  C CG  . PHE D 2 56  ? 173.945 174.429 211.066 1.00 59.59  ? 72  PHE E CG  1 
ATOM   8463  C CD1 . PHE D 2 56  ? 174.615 173.941 209.959 1.00 59.08  ? 72  PHE E CD1 1 
ATOM   8464  C CD2 . PHE D 2 56  ? 173.813 173.612 212.175 1.00 58.68  ? 72  PHE E CD2 1 
ATOM   8465  C CE1 . PHE D 2 56  ? 175.143 172.666 209.960 1.00 60.26  ? 72  PHE E CE1 1 
ATOM   8466  C CE2 . PHE D 2 56  ? 174.339 172.337 212.181 1.00 58.95  ? 72  PHE E CE2 1 
ATOM   8467  C CZ  . PHE D 2 56  ? 175.005 171.864 211.074 1.00 60.51  ? 72  PHE E CZ  1 
ATOM   8468  N N   . GLN D 2 57  ? 174.380 178.939 210.081 1.00 53.19  ? 73  GLN E N   1 
ATOM   8469  C CA  . GLN D 2 57  ? 173.913 180.246 209.621 1.00 47.45  ? 73  GLN E CA  1 
ATOM   8470  C C   . GLN D 2 57  ? 173.033 180.020 208.397 1.00 46.20  ? 73  GLN E C   1 
ATOM   8471  O O   . GLN D 2 57  ? 173.528 179.926 207.272 1.00 46.56  ? 73  GLN E O   1 
ATOM   8472  C CB  . GLN D 2 57  ? 175.089 181.163 209.307 1.00 50.89  ? 73  GLN E CB  1 
ATOM   8473  C CG  . GLN D 2 57  ? 175.951 181.499 210.509 1.00 53.82  ? 73  GLN E CG  1 
ATOM   8474  C CD  . GLN D 2 57  ? 175.217 182.339 211.532 1.00 58.44  ? 73  GLN E CD  1 
ATOM   8475  O OE1 . GLN D 2 57  ? 175.207 182.022 212.721 1.00 59.30  ? 73  GLN E OE1 1 
ATOM   8476  N NE2 . GLN D 2 57  ? 174.596 183.419 211.074 1.00 58.00  ? 73  GLN E NE2 1 
ATOM   8477  N N   . LEU D 2 58  ? 171.726 179.938 208.618 1.00 44.57  ? 74  LEU E N   1 
ATOM   8478  C CA  . LEU D 2 58  ? 170.771 179.603 207.575 1.00 42.17  ? 74  LEU E CA  1 
ATOM   8479  C C   . LEU D 2 58  ? 169.814 180.764 207.340 1.00 42.81  ? 74  LEU E C   1 
ATOM   8480  O O   . LEU D 2 58  ? 169.775 181.737 208.096 1.00 44.26  ? 74  LEU E O   1 
ATOM   8481  C CB  . LEU D 2 58  ? 169.987 178.335 207.933 1.00 39.64  ? 74  LEU E CB  1 
ATOM   8482  C CG  . LEU D 2 58  ? 170.815 177.135 208.388 1.00 41.22  ? 74  LEU E CG  1 
ATOM   8483  C CD1 . LEU D 2 58  ? 169.949 176.160 209.159 1.00 44.27  ? 74  LEU E CD1 1 
ATOM   8484  C CD2 . LEU D 2 58  ? 171.466 176.455 207.200 1.00 39.79  ? 74  LEU E CD2 1 
ATOM   8485  N N   . HIS D 2 59  ? 169.035 180.642 206.271 1.00 39.57  ? 75  HIS E N   1 
ATOM   8486  C CA  . HIS D 2 59  ? 168.082 181.659 205.853 1.00 35.26  ? 75  HIS E CA  1 
ATOM   8487  C C   . HIS D 2 59  ? 166.670 181.162 206.124 1.00 34.06  ? 75  HIS E C   1 
ATOM   8488  O O   . HIS D 2 59  ? 166.328 180.034 205.759 1.00 36.07  ? 75  HIS E O   1 
ATOM   8489  C CB  . HIS D 2 59  ? 168.254 181.986 204.369 1.00 37.26  ? 75  HIS E CB  1 
ATOM   8490  C CG  . HIS D 2 59  ? 169.666 182.288 203.975 1.00 38.71  ? 75  HIS E CG  1 
ATOM   8491  N ND1 . HIS D 2 59  ? 170.647 181.323 203.920 1.00 39.32  ? 75  HIS E ND1 1 
ATOM   8492  C CD2 . HIS D 2 59  ? 170.259 183.447 203.605 1.00 43.84  ? 75  HIS E CD2 1 
ATOM   8493  C CE1 . HIS D 2 59  ? 171.786 181.875 203.542 1.00 43.50  ? 75  HIS E CE1 1 
ATOM   8494  N NE2 . HIS D 2 59  ? 171.577 183.163 203.342 1.00 46.15  ? 75  HIS E NE2 1 
ATOM   8495  N N   . ARG D 2 60  ? 165.854 182.004 206.762 1.00 34.15  ? 76  ARG E N   1 
ATOM   8496  C CA  . ARG D 2 60  ? 164.496 181.597 207.104 1.00 33.62  ? 76  ARG E CA  1 
ATOM   8497  C C   . ARG D 2 60  ? 163.637 181.385 205.866 1.00 35.08  ? 76  ARG E C   1 
ATOM   8498  O O   . ARG D 2 60  ? 162.734 180.541 205.878 1.00 35.05  ? 76  ARG E O   1 
ATOM   8499  C CB  . ARG D 2 60  ? 163.848 182.632 208.023 1.00 39.03  ? 76  ARG E CB  1 
ATOM   8500  C CG  . ARG D 2 60  ? 164.553 182.812 209.350 1.00 43.15  ? 76  ARG E CG  1 
ATOM   8501  C CD  . ARG D 2 60  ? 163.640 183.447 210.379 1.00 44.73  ? 76  ARG E CD  1 
ATOM   8502  N NE  . ARG D 2 60  ? 163.078 184.707 209.911 1.00 47.78  ? 76  ARG E NE  1 
ATOM   8503  C CZ  . ARG D 2 60  ? 163.412 185.898 210.385 1.00 52.22  ? 76  ARG E CZ  1 
ATOM   8504  N NH1 . ARG D 2 60  ? 164.308 186.032 211.348 1.00 51.60  ? 76  ARG E NH1 1 
ATOM   8505  N NH2 . ARG D 2 60  ? 162.829 186.983 209.883 1.00 54.65  ? 76  ARG E NH2 1 
ATOM   8506  N N   . LEU D 2 61  ? 163.896 182.135 204.794 1.00 37.35  ? 77  LEU E N   1 
ATOM   8507  C CA  . LEU D 2 61  ? 163.078 182.019 203.591 1.00 33.31  ? 77  LEU E CA  1 
ATOM   8508  C C   . LEU D 2 61  ? 163.268 180.664 202.918 1.00 30.89  ? 77  LEU E C   1 
ATOM   8509  O O   . LEU D 2 61  ? 162.293 180.008 202.535 1.00 32.20  ? 77  LEU E O   1 
ATOM   8510  C CB  . LEU D 2 61  ? 163.411 183.156 202.626 1.00 33.76  ? 77  LEU E CB  1 
ATOM   8511  C CG  . LEU D 2 61  ? 162.461 183.360 201.445 1.00 39.52  ? 77  LEU E CG  1 
ATOM   8512  C CD1 . LEU D 2 61  ? 161.218 184.110 201.883 1.00 40.48  ? 77  LEU E CD1 1 
ATOM   8513  C CD2 . LEU D 2 61  ? 163.164 184.095 200.320 1.00 33.99  ? 77  LEU E CD2 1 
ATOM   8514  N N   . VAL D 2 62  ? 164.519 180.225 202.773 1.00 30.14  ? 78  VAL E N   1 
ATOM   8515  C CA  . VAL D 2 62  ? 164.789 178.951 202.113 1.00 29.14  ? 78  VAL E CA  1 
ATOM   8516  C C   . VAL D 2 62  ? 164.273 177.790 202.953 1.00 30.32  ? 78  VAL E C   1 
ATOM   8517  O O   . VAL D 2 62  ? 163.785 176.789 202.417 1.00 32.87  ? 78  VAL E O   1 
ATOM   8518  C CB  . VAL D 2 62  ? 166.293 178.810 201.817 1.00 31.51  ? 78  VAL E CB  1 
ATOM   8519  C CG1 . VAL D 2 62  ? 166.539 177.651 200.865 1.00 31.07  ? 78  VAL E CG1 1 
ATOM   8520  C CG2 . VAL D 2 62  ? 166.845 180.104 201.243 1.00 30.21  ? 78  VAL E CG2 1 
ATOM   8521  N N   . LEU D 2 63  ? 164.388 177.894 204.277 1.00 31.14  ? 79  LEU E N   1 
ATOM   8522  C CA  . LEU D 2 63  ? 163.884 176.834 205.144 1.00 29.13  ? 79  LEU E CA  1 
ATOM   8523  C C   . LEU D 2 63  ? 162.361 176.777 205.127 1.00 30.77  ? 79  LEU E C   1 
ATOM   8524  O O   . LEU D 2 63  ? 161.777 175.689 205.106 1.00 36.11  ? 79  LEU E O   1 
ATOM   8525  C CB  . LEU D 2 63  ? 164.401 177.030 206.568 1.00 30.99  ? 79  LEU E CB  1 
ATOM   8526  C CG  . LEU D 2 63  ? 165.915 176.933 206.751 1.00 29.03  ? 79  LEU E CG  1 
ATOM   8527  C CD1 . LEU D 2 63  ? 166.320 177.421 208.127 1.00 31.95  ? 79  LEU E CD1 1 
ATOM   8528  C CD2 . LEU D 2 63  ? 166.384 175.510 206.535 1.00 29.75  ? 79  LEU E CD2 1 
ATOM   8529  N N   . SER D 2 64  ? 161.699 177.936 205.134 1.00 31.73  ? 80  SER E N   1 
ATOM   8530  C CA  . SER D 2 64  ? 160.241 177.963 205.145 1.00 32.78  ? 80  SER E CA  1 
ATOM   8531  C C   . SER D 2 64  ? 159.638 177.605 203.794 1.00 34.04  ? 80  SER E C   1 
ATOM   8532  O O   . SER D 2 64  ? 158.499 177.130 203.749 1.00 38.10  ? 80  SER E O   1 
ATOM   8533  C CB  . SER D 2 64  ? 159.745 179.340 205.583 1.00 36.15  ? 80  SER E CB  1 
ATOM   8534  O OG  . SER D 2 64  ? 160.552 179.859 206.623 1.00 40.72  ? 80  SER E OG  1 
ATOM   8535  N N   . ALA D 2 65  ? 160.363 177.826 202.698 1.00 34.64  ? 81  ALA E N   1 
ATOM   8536  C CA  . ALA D 2 65  ? 159.870 177.443 201.383 1.00 34.33  ? 81  ALA E CA  1 
ATOM   8537  C C   . ALA D 2 65  ? 159.932 175.943 201.141 1.00 35.54  ? 81  ALA E C   1 
ATOM   8538  O O   . ALA D 2 65  ? 159.272 175.453 200.220 1.00 37.11  ? 81  ALA E O   1 
ATOM   8539  C CB  . ALA D 2 65  ? 160.663 178.166 200.294 1.00 32.81  ? 81  ALA E CB  1 
ATOM   8540  N N   . GLN D 2 66  ? 160.700 175.208 201.941 1.00 35.31  ? 82  GLN E N   1 
ATOM   8541  C CA  . GLN D 2 66  ? 160.877 173.773 201.767 1.00 35.61  ? 82  GLN E CA  1 
ATOM   8542  C C   . GLN D 2 66  ? 160.067 172.946 202.754 1.00 38.28  ? 82  GLN E C   1 
ATOM   8543  O O   . GLN D 2 66  ? 159.654 171.831 202.424 1.00 45.54  ? 82  GLN E O   1 
ATOM   8544  C CB  . GLN D 2 66  ? 162.359 173.408 201.901 1.00 32.20  ? 82  GLN E CB  1 
ATOM   8545  C CG  . GLN D 2 66  ? 162.817 172.315 200.957 1.00 34.31  ? 82  GLN E CG  1 
ATOM   8546  C CD  . GLN D 2 66  ? 163.255 172.855 199.615 1.00 31.94  ? 82  GLN E CD  1 
ATOM   8547  O OE1 . GLN D 2 66  ? 163.405 174.061 199.441 1.00 31.19  ? 82  GLN E OE1 1 
ATOM   8548  N NE2 . GLN D 2 66  ? 163.468 171.961 198.658 1.00 30.28  ? 82  GLN E NE2 1 
ATOM   8549  N N   . SER D 2 67  ? 159.830 173.460 203.956 1.00 35.68  ? 83  SER E N   1 
ATOM   8550  C CA  . SER D 2 67  ? 159.158 172.706 205.001 1.00 38.17  ? 83  SER E CA  1 
ATOM   8551  C C   . SER D 2 67  ? 158.119 173.571 205.695 1.00 42.75  ? 83  SER E C   1 
ATOM   8552  O O   . SER D 2 67  ? 158.261 174.793 205.785 1.00 45.18  ? 83  SER E O   1 
ATOM   8553  C CB  . SER D 2 67  ? 160.159 172.179 206.030 1.00 34.20  ? 83  SER E CB  1 
ATOM   8554  O OG  . SER D 2 67  ? 160.986 173.217 206.516 1.00 35.82  ? 83  SER E OG  1 
ATOM   8555  N N   . CYS D 2 68  ? 157.067 172.919 206.188 1.00 46.02  ? 84  CYS E N   1 
ATOM   8556  C CA  . CYS D 2 68  ? 156.062 173.593 206.998 1.00 45.49  ? 84  CYS E CA  1 
ATOM   8557  C C   . CYS D 2 68  ? 156.423 173.599 208.475 1.00 42.38  ? 84  CYS E C   1 
ATOM   8558  O O   . CYS D 2 68  ? 155.997 174.500 209.207 1.00 43.10  ? 84  CYS E O   1 
ATOM   8559  C CB  . CYS D 2 68  ? 154.697 172.929 206.805 1.00 44.84  ? 84  CYS E CB  1 
ATOM   8560  S SG  . CYS D 2 68  ? 154.377 172.374 205.117 1.00 67.03  ? 84  CYS E SG  1 
ATOM   8561  N N   . PHE D 2 69  ? 157.203 172.613 208.924 1.00 40.73  ? 85  PHE E N   1 
ATOM   8562  C CA  . PHE D 2 69  ? 157.686 172.611 210.300 1.00 40.45  ? 85  PHE E CA  1 
ATOM   8563  C C   . PHE D 2 69  ? 158.521 173.853 210.577 1.00 42.86  ? 85  PHE E C   1 
ATOM   8564  O O   . PHE D 2 69  ? 158.281 174.573 211.552 1.00 43.37  ? 85  PHE E O   1 
ATOM   8565  C CB  . PHE D 2 69  ? 158.490 171.333 210.561 1.00 38.03  ? 85  PHE E CB  1 
ATOM   8566  C CG  . PHE D 2 69  ? 159.276 171.347 211.845 1.00 36.86  ? 85  PHE E CG  1 
ATOM   8567  C CD1 . PHE D 2 69  ? 160.578 171.821 211.878 1.00 37.52  ? 85  PHE E CD1 1 
ATOM   8568  C CD2 . PHE D 2 69  ? 158.717 170.867 213.015 1.00 38.06  ? 85  PHE E CD2 1 
ATOM   8569  C CE1 . PHE D 2 69  ? 161.298 171.829 213.054 1.00 39.60  ? 85  PHE E CE1 1 
ATOM   8570  C CE2 . PHE D 2 69  ? 159.434 170.871 214.194 1.00 41.74  ? 85  PHE E CE2 1 
ATOM   8571  C CZ  . PHE D 2 69  ? 160.726 171.353 214.213 1.00 42.61  ? 85  PHE E CZ  1 
ATOM   8572  N N   . PHE D 2 70  ? 159.497 174.134 209.709 1.00 44.69  ? 86  PHE E N   1 
ATOM   8573  C CA  . PHE D 2 70  ? 160.326 175.321 209.880 1.00 40.68  ? 86  PHE E CA  1 
ATOM   8574  C C   . PHE D 2 70  ? 159.531 176.602 209.673 1.00 45.18  ? 86  PHE E C   1 
ATOM   8575  O O   . PHE D 2 70  ? 159.830 177.618 210.305 1.00 46.67  ? 86  PHE E O   1 
ATOM   8576  C CB  . PHE D 2 70  ? 161.514 175.280 208.921 1.00 36.75  ? 86  PHE E CB  1 
ATOM   8577  C CG  . PHE D 2 70  ? 162.716 174.574 209.476 1.00 40.07  ? 86  PHE E CG  1 
ATOM   8578  C CD1 . PHE D 2 70  ? 163.352 175.050 210.607 1.00 41.67  ? 86  PHE E CD1 1 
ATOM   8579  C CD2 . PHE D 2 70  ? 163.211 173.436 208.864 1.00 36.99  ? 86  PHE E CD2 1 
ATOM   8580  C CE1 . PHE D 2 70  ? 164.457 174.405 211.119 1.00 38.66  ? 86  PHE E CE1 1 
ATOM   8581  C CE2 . PHE D 2 70  ? 164.316 172.789 209.372 1.00 35.65  ? 86  PHE E CE2 1 
ATOM   8582  C CZ  . PHE D 2 70  ? 164.939 173.274 210.501 1.00 37.77  ? 86  PHE E CZ  1 
ATOM   8583  N N   . ARG D 2 71  ? 158.528 176.583 208.795 1.00 46.97  ? 87  ARG E N   1 
ATOM   8584  C CA  . ARG D 2 71  ? 157.713 177.776 208.588 1.00 44.00  ? 87  ARG E CA  1 
ATOM   8585  C C   . ARG D 2 71  ? 156.922 178.124 209.844 1.00 46.85  ? 87  ARG E C   1 
ATOM   8586  O O   . ARG D 2 71  ? 156.918 179.277 210.287 1.00 51.81  ? 87  ARG E O   1 
ATOM   8587  C CB  . ARG D 2 71  ? 156.776 177.575 207.399 1.00 46.92  ? 87  ARG E CB  1 
ATOM   8588  C CG  . ARG D 2 71  ? 155.814 178.725 207.181 1.00 52.33  ? 87  ARG E CG  1 
ATOM   8589  C CD  . ARG D 2 71  ? 154.816 178.418 206.073 1.00 59.96  ? 87  ARG E CD  1 
ATOM   8590  N NE  . ARG D 2 71  ? 154.124 179.603 205.574 1.00 71.25  ? 87  ARG E NE  1 
ATOM   8591  C CZ  . ARG D 2 71  ? 153.408 180.444 206.311 1.00 72.42  ? 87  ARG E CZ  1 
ATOM   8592  N NH1 . ARG D 2 71  ? 153.197 180.235 207.600 1.00 69.82  ? 87  ARG E NH1 1 
ATOM   8593  N NH2 . ARG D 2 71  ? 152.872 181.514 205.733 1.00 71.56  ? 87  ARG E NH2 1 
ATOM   8594  N N   . SER D 2 72  ? 156.245 177.135 210.433 1.00 46.18  ? 88  SER E N   1 
ATOM   8595  C CA  . SER D 2 72  ? 155.506 177.379 211.668 1.00 44.14  ? 88  SER E CA  1 
ATOM   8596  C C   . SER D 2 72  ? 156.443 177.686 212.829 1.00 48.11  ? 88  SER E C   1 
ATOM   8597  O O   . SER D 2 72  ? 156.082 178.451 213.730 1.00 54.52  ? 88  SER E O   1 
ATOM   8598  C CB  . SER D 2 72  ? 154.624 176.178 212.001 1.00 44.62  ? 88  SER E CB  1 
ATOM   8599  O OG  . SER D 2 72  ? 154.031 175.643 210.831 1.00 46.97  ? 88  SER E OG  1 
ATOM   8600  N N   . MET D 2 73  ? 157.637 177.093 212.829 1.00 49.44  ? 89  MET E N   1 
ATOM   8601  C CA  . MET D 2 73  ? 158.647 177.411 213.829 1.00 50.06  ? 89  MET E CA  1 
ATOM   8602  C C   . MET D 2 73  ? 159.111 178.857 213.729 1.00 49.13  ? 89  MET E C   1 
ATOM   8603  O O   . MET D 2 73  ? 159.332 179.509 214.755 1.00 51.67  ? 89  MET E O   1 
ATOM   8604  C CB  . MET D 2 73  ? 159.824 176.451 213.661 1.00 50.09  ? 89  MET E CB  1 
ATOM   8605  C CG  . MET D 2 73  ? 161.167 176.969 214.118 1.00 49.43  ? 89  MET E CG  1 
ATOM   8606  S SD  . MET D 2 73  ? 162.382 175.643 214.083 1.00 56.00  ? 89  MET E SD  1 
ATOM   8607  C CE  . MET D 2 73  ? 163.793 176.457 214.808 1.00 60.99  ? 89  MET E CE  1 
ATOM   8608  N N   . PHE D 2 74  ? 159.261 179.371 212.510 1.00 52.48  ? 90  PHE E N   1 
ATOM   8609  C CA  . PHE D 2 74  ? 159.811 180.700 212.284 1.00 54.02  ? 90  PHE E CA  1 
ATOM   8610  C C   . PHE D 2 74  ? 158.761 181.797 212.385 1.00 56.60  ? 90  PHE E C   1 
ATOM   8611  O O   . PHE D 2 74  ? 159.044 182.866 212.937 1.00 61.44  ? 90  PHE E O   1 
ATOM   8612  C CB  . PHE D 2 74  ? 160.486 180.758 210.912 1.00 47.97  ? 90  PHE E CB  1 
ATOM   8613  C CG  . PHE D 2 74  ? 161.841 180.120 210.880 1.00 45.19  ? 90  PHE E CG  1 
ATOM   8614  C CD1 . PHE D 2 74  ? 162.689 180.213 211.968 1.00 43.75  ? 90  PHE E CD1 1 
ATOM   8615  C CD2 . PHE D 2 74  ? 162.265 179.421 209.766 1.00 43.46  ? 90  PHE E CD2 1 
ATOM   8616  C CE1 . PHE D 2 74  ? 163.935 179.626 211.943 1.00 44.49  ? 90  PHE E CE1 1 
ATOM   8617  C CE2 . PHE D 2 74  ? 163.508 178.832 209.736 1.00 41.38  ? 90  PHE E CE2 1 
ATOM   8618  C CZ  . PHE D 2 74  ? 164.345 178.934 210.824 1.00 42.07  ? 90  PHE E CZ  1 
ATOM   8619  N N   . THR D 2 75  ? 157.559 181.568 211.851 1.00 57.03  ? 91  THR E N   1 
ATOM   8620  C CA  . THR D 2 75  ? 156.542 182.611 211.866 1.00 64.10  ? 91  THR E CA  1 
ATOM   8621  C C   . THR D 2 75  ? 156.165 182.970 213.296 1.00 73.90  ? 91  THR E C   1 
ATOM   8622  O O   . THR D 2 75  ? 156.517 184.055 213.768 1.00 83.81  ? 91  THR E O   1 
ATOM   8623  C CB  . THR D 2 75  ? 155.303 182.161 211.089 1.00 63.72  ? 91  THR E CB  1 
ATOM   8624  O OG1 . THR D 2 75  ? 155.677 181.810 209.751 1.00 61.23  ? 91  THR E OG1 1 
ATOM   8625  C CG2 . THR D 2 75  ? 154.270 183.271 211.045 1.00 72.32  ? 91  THR E CG2 1 
ATOM   8626  N N   . SER D 2 76  ? 155.453 182.067 213.980 1.00 69.86  ? 92  SER E N   1 
ATOM   8627  C CA  . SER D 2 76  ? 155.355 181.995 215.438 1.00 78.70  ? 92  SER E CA  1 
ATOM   8628  C C   . SER D 2 76  ? 155.421 183.351 216.131 1.00 89.72  ? 92  SER E C   1 
ATOM   8629  O O   . SER D 2 76  ? 156.189 183.514 217.084 1.00 94.57  ? 92  SER E O   1 
ATOM   8630  C CB  . SER D 2 76  ? 156.455 181.088 215.990 1.00 78.69  ? 92  SER E CB  1 
ATOM   8631  O OG  . SER D 2 76  ? 156.344 180.960 217.395 1.00 86.48  ? 92  SER E OG  1 
ATOM   8632  N N   . ASN D 2 77  ? 154.602 184.314 215.706 1.00 91.13  ? 93  ASN E N   1 
ATOM   8633  C CA  . ASN D 2 77  ? 154.907 185.717 215.975 1.00 93.70  ? 93  ASN E CA  1 
ATOM   8634  C C   . ASN D 2 77  ? 154.768 186.062 217.452 1.00 96.39  ? 93  ASN E C   1 
ATOM   8635  O O   . ASN D 2 77  ? 153.870 186.812 217.848 1.00 95.59  ? 93  ASN E O   1 
ATOM   8636  C CB  . ASN D 2 77  ? 154.009 186.627 215.134 1.00 93.12  ? 93  ASN E CB  1 
ATOM   8637  C CG  . ASN D 2 77  ? 154.160 186.379 213.645 1.00 86.03  ? 93  ASN E CG  1 
ATOM   8638  O OD1 . ASN D 2 77  ? 155.163 186.759 213.039 1.00 80.96  ? 93  ASN E OD1 1 
ATOM   8639  N ND2 . ASN D 2 77  ? 153.158 185.747 213.045 1.00 81.30  ? 93  ASN E ND2 1 
ATOM   8640  N N   . LEU D 2 78  ? 155.694 185.547 218.252 1.00 100.91 ? 94  LEU E N   1 
ATOM   8641  C CA  . LEU D 2 78  ? 155.772 185.745 219.696 1.00 105.80 ? 94  LEU E CA  1 
ATOM   8642  C C   . LEU D 2 78  ? 157.252 185.794 220.067 1.00 109.55 ? 94  LEU E C   1 
ATOM   8643  O O   . LEU D 2 78  ? 158.112 186.008 219.206 1.00 108.10 ? 94  LEU E O   1 
ATOM   8644  C CB  . LEU D 2 78  ? 155.020 184.638 220.461 1.00 103.34 ? 94  LEU E CB  1 
ATOM   8645  C CG  . LEU D 2 78  ? 153.534 184.293 220.285 1.00 102.81 ? 94  LEU E CG  1 
ATOM   8646  C CD1 . LEU D 2 78  ? 152.647 185.533 220.310 1.00 100.91 ? 94  LEU E CD1 1 
ATOM   8647  C CD2 . LEU D 2 78  ? 153.284 183.460 219.029 1.00 97.90  ? 94  LEU E CD2 1 
ATOM   8648  N N   . LYS D 2 79  ? 157.551 185.607 221.355 1.00 112.38 ? 95  LYS E N   1 
ATOM   8649  C CA  . LYS D 2 79  ? 158.935 185.673 221.818 1.00 114.59 ? 95  LYS E CA  1 
ATOM   8650  C C   . LYS D 2 79  ? 159.801 184.606 221.156 1.00 112.97 ? 95  LYS E C   1 
ATOM   8651  O O   . LYS D 2 79  ? 160.946 184.876 220.775 1.00 111.10 ? 95  LYS E O   1 
ATOM   8652  C CB  . LYS D 2 79  ? 158.981 185.536 223.341 1.00 115.20 ? 95  LYS E CB  1 
ATOM   8653  C CG  . LYS D 2 79  ? 160.358 185.218 223.914 1.00 115.22 ? 95  LYS E CG  1 
ATOM   8654  C CD  . LYS D 2 79  ? 161.368 186.321 223.619 1.00 116.22 ? 95  LYS E CD  1 
ATOM   8655  C CE  . LYS D 2 79  ? 160.938 187.650 224.219 1.00 118.92 ? 95  LYS E CE  1 
ATOM   8656  N NZ  . LYS D 2 79  ? 162.005 188.681 224.096 1.00 119.87 ? 95  LYS E NZ  1 
ATOM   8657  N N   . GLU D 2 80  ? 159.275 183.389 221.005 1.00 111.49 ? 96  GLU E N   1 
ATOM   8658  C CA  . GLU D 2 80  ? 160.078 182.291 220.477 1.00 112.58 ? 96  GLU E CA  1 
ATOM   8659  C C   . GLU D 2 80  ? 160.408 182.446 218.996 1.00 111.72 ? 96  GLU E C   1 
ATOM   8660  O O   . GLU D 2 80  ? 161.224 181.673 218.482 1.00 108.77 ? 96  GLU E O   1 
ATOM   8661  C CB  . GLU D 2 80  ? 159.375 180.950 220.709 1.00 110.01 ? 96  GLU E CB  1 
ATOM   8662  C CG  . GLU D 2 80  ? 157.986 180.835 220.107 1.00 110.03 ? 96  GLU E CG  1 
ATOM   8663  C CD  . GLU D 2 80  ? 156.911 181.453 220.976 1.00 112.03 ? 96  GLU E CD  1 
ATOM   8664  O OE1 . GLU D 2 80  ? 157.208 181.794 222.140 1.00 112.95 ? 96  GLU E OE1 1 
ATOM   8665  O OE2 . GLU D 2 80  ? 155.766 181.585 220.497 1.00 109.71 ? 96  GLU E OE2 1 
ATOM   8666  N N   . ALA D 2 81  ? 159.795 183.403 218.297 1.00 108.41 ? 97  ALA E N   1 
ATOM   8667  C CA  . ALA D 2 81  ? 160.155 183.646 216.904 1.00 103.64 ? 97  ALA E CA  1 
ATOM   8668  C C   . ALA D 2 81  ? 161.412 184.502 216.804 1.00 109.66 ? 97  ALA E C   1 
ATOM   8669  O O   . ALA D 2 81  ? 162.370 184.143 216.110 1.00 109.87 ? 97  ALA E O   1 
ATOM   8670  C CB  . ALA D 2 81  ? 158.996 184.314 216.163 1.00 96.24  ? 97  ALA E CB  1 
ATOM   8671  N N   . HIS D 2 82  ? 161.421 185.646 217.488 1.00 109.63 ? 98  HIS E N   1 
ATOM   8672  C CA  . HIS D 2 82  ? 162.562 186.560 217.452 1.00 110.06 ? 98  HIS E CA  1 
ATOM   8673  C C   . HIS D 2 82  ? 163.532 186.213 218.583 1.00 110.93 ? 98  HIS E C   1 
ATOM   8674  O O   . HIS D 2 82  ? 163.749 186.970 219.531 1.00 111.65 ? 98  HIS E O   1 
ATOM   8675  C CB  . HIS D 2 82  ? 162.088 188.006 217.531 1.00 112.93 ? 98  HIS E CB  1 
ATOM   8676  C CG  . HIS D 2 82  ? 161.186 188.287 218.693 1.00 117.08 ? 98  HIS E CG  1 
ATOM   8677  N ND1 . HIS D 2 82  ? 161.626 188.269 219.999 1.00 116.82 ? 98  HIS E ND1 1 
ATOM   8678  C CD2 . HIS D 2 82  ? 159.869 188.596 218.745 1.00 116.01 ? 98  HIS E CD2 1 
ATOM   8679  C CE1 . HIS D 2 82  ? 160.619 188.553 220.805 1.00 114.83 ? 98  HIS E CE1 1 
ATOM   8680  N NE2 . HIS D 2 82  ? 159.541 188.755 220.069 1.00 115.36 ? 98  HIS E NE2 1 
ATOM   8681  N N   . ASN D 2 83  ? 164.125 185.029 218.458 1.00 109.25 ? 99  ASN E N   1 
ATOM   8682  C CA  . ASN D 2 83  ? 165.150 184.560 219.376 1.00 106.14 ? 99  ASN E CA  1 
ATOM   8683  C C   . ASN D 2 83  ? 166.457 184.383 218.617 1.00 101.79 ? 99  ASN E C   1 
ATOM   8684  O O   . ASN D 2 83  ? 166.464 184.042 217.430 1.00 99.42  ? 99  ASN E O   1 
ATOM   8685  C CB  . ASN D 2 83  ? 164.744 183.244 220.053 1.00 105.65 ? 99  ASN E CB  1 
ATOM   8686  C CG  . ASN D 2 83  ? 164.152 182.244 219.081 1.00 105.65 ? 99  ASN E CG  1 
ATOM   8687  O OD1 . ASN D 2 83  ? 163.846 182.579 217.937 1.00 105.59 ? 99  ASN E OD1 1 
ATOM   8688  N ND2 . ASN D 2 83  ? 163.976 181.010 219.537 1.00 101.02 ? 99  ASN E ND2 1 
ATOM   8689  N N   . ARG D 2 84  ? 167.567 184.628 219.315 1.00 101.12 ? 100 ARG E N   1 
ATOM   8690  C CA  . ARG D 2 84  ? 168.872 184.645 218.662 1.00 99.39  ? 100 ARG E CA  1 
ATOM   8691  C C   . ARG D 2 84  ? 169.244 183.266 218.129 1.00 93.24  ? 100 ARG E C   1 
ATOM   8692  O O   . ARG D 2 84  ? 169.439 183.082 216.923 1.00 89.06  ? 100 ARG E O   1 
ATOM   8693  C CB  . ARG D 2 84  ? 169.935 185.156 219.636 1.00 97.27  ? 100 ARG E CB  1 
ATOM   8694  C CG  . ARG D 2 84  ? 169.879 186.655 219.899 1.00 101.58 ? 100 ARG E CG  1 
ATOM   8695  C CD  . ARG D 2 84  ? 169.334 187.422 218.703 1.00 104.99 ? 100 ARG E CD  1 
ATOM   8696  N NE  . ARG D 2 84  ? 167.983 187.916 218.942 1.00 107.60 ? 100 ARG E NE  1 
ATOM   8697  C CZ  . ARG D 2 84  ? 167.020 187.934 218.031 1.00 109.90 ? 100 ARG E CZ  1 
ATOM   8698  N NH1 . ARG D 2 84  ? 167.222 187.489 216.802 1.00 109.93 ? 100 ARG E NH1 1 
ATOM   8699  N NH2 . ARG D 2 84  ? 165.823 188.412 218.361 1.00 109.51 ? 100 ARG E NH2 1 
ATOM   8700  N N   . VAL D 2 85  ? 169.345 182.282 219.018 1.00 89.04  ? 101 VAL E N   1 
ATOM   8701  C CA  . VAL D 2 85  ? 169.782 180.938 218.663 1.00 83.46  ? 101 VAL E CA  1 
ATOM   8702  C C   . VAL D 2 85  ? 168.702 179.953 219.083 1.00 85.26  ? 101 VAL E C   1 
ATOM   8703  O O   . VAL D 2 85  ? 168.227 179.994 220.224 1.00 87.95  ? 101 VAL E O   1 
ATOM   8704  C CB  . VAL D 2 85  ? 171.127 180.589 219.326 1.00 80.65  ? 101 VAL E CB  1 
ATOM   8705  C CG1 . VAL D 2 85  ? 171.459 179.125 219.114 1.00 75.27  ? 101 VAL E CG1 1 
ATOM   8706  C CG2 . VAL D 2 85  ? 172.235 181.480 218.786 1.00 82.13  ? 101 VAL E CG2 1 
ATOM   8707  N N   . ILE D 2 86  ? 168.314 179.073 218.164 1.00 79.65  ? 102 ILE E N   1 
ATOM   8708  C CA  . ILE D 2 86  ? 167.337 178.026 218.434 1.00 79.62  ? 102 ILE E CA  1 
ATOM   8709  C C   . ILE D 2 86  ? 168.060 176.690 218.366 1.00 77.01  ? 102 ILE E C   1 
ATOM   8710  O O   . ILE D 2 86  ? 168.750 176.399 217.382 1.00 72.15  ? 102 ILE E O   1 
ATOM   8711  C CB  . ILE D 2 86  ? 166.167 178.066 217.442 1.00 78.35  ? 102 ILE E CB  1 
ATOM   8712  C CG1 . ILE D 2 86  ? 165.762 179.511 217.154 1.00 82.25  ? 102 ILE E CG1 1 
ATOM   8713  C CG2 . ILE D 2 86  ? 164.987 177.295 218.009 1.00 80.76  ? 102 ILE E CG2 1 
ATOM   8714  C CD1 . ILE D 2 86  ? 165.420 179.770 215.705 1.00 75.15  ? 102 ILE E CD1 1 
ATOM   8715  N N   . VAL D 2 87  ? 167.905 175.880 219.406 1.00 77.55  ? 103 VAL E N   1 
ATOM   8716  C CA  . VAL D 2 87  ? 168.577 174.589 219.487 1.00 75.29  ? 103 VAL E CA  1 
ATOM   8717  C C   . VAL D 2 87  ? 167.610 173.485 219.085 1.00 74.92  ? 103 VAL E C   1 
ATOM   8718  O O   . VAL D 2 87  ? 166.403 173.561 219.347 1.00 77.04  ? 103 VAL E O   1 
ATOM   8719  C CB  . VAL D 2 87  ? 169.152 174.356 220.899 1.00 75.87  ? 103 VAL E CB  1 
ATOM   8720  C CG1 . VAL D 2 87  ? 169.927 175.578 221.359 1.00 74.63  ? 103 VAL E CG1 1 
ATOM   8721  C CG2 . VAL D 2 87  ? 168.048 174.027 221.891 1.00 75.62  ? 103 VAL E CG2 1 
ATOM   8722  N N   . LEU D 2 88  ? 168.139 172.469 218.411 1.00 71.18  ? 104 LEU E N   1 
ATOM   8723  C CA  . LEU D 2 88  ? 167.386 171.283 218.033 1.00 72.51  ? 104 LEU E CA  1 
ATOM   8724  C C   . LEU D 2 88  ? 167.991 170.071 218.728 1.00 78.93  ? 104 LEU E C   1 
ATOM   8725  O O   . LEU D 2 88  ? 169.215 169.912 218.762 1.00 79.31  ? 104 LEU E O   1 
ATOM   8726  C CB  . LEU D 2 88  ? 167.392 171.090 216.514 1.00 66.13  ? 104 LEU E CB  1 
ATOM   8727  C CG  . LEU D 2 88  ? 166.718 172.199 215.704 1.00 59.45  ? 104 LEU E CG  1 
ATOM   8728  C CD1 . LEU D 2 88  ? 166.903 171.970 214.218 1.00 50.90  ? 104 LEU E CD1 1 
ATOM   8729  C CD2 . LEU D 2 88  ? 165.243 172.295 216.046 1.00 61.51  ? 104 LEU E CD2 1 
ATOM   8730  N N   . GLN D 2 89  ? 167.132 169.220 219.290 1.00 74.70  ? 105 GLN E N   1 
ATOM   8731  C CA  . GLN D 2 89  ? 167.589 168.145 220.158 1.00 78.28  ? 105 GLN E CA  1 
ATOM   8732  C C   . GLN D 2 89  ? 167.318 166.742 219.635 1.00 78.87  ? 105 GLN E C   1 
ATOM   8733  O O   . GLN D 2 89  ? 167.883 165.786 220.177 1.00 81.99  ? 105 GLN E O   1 
ATOM   8734  C CB  . GLN D 2 89  ? 166.955 168.284 221.551 1.00 81.92  ? 105 GLN E CB  1 
ATOM   8735  C CG  . GLN D 2 89  ? 167.394 169.529 222.301 1.00 84.19  ? 105 GLN E CG  1 
ATOM   8736  C CD  . GLN D 2 89  ? 167.287 169.373 223.803 1.00 91.93  ? 105 GLN E CD  1 
ATOM   8737  O OE1 . GLN D 2 89  ? 166.653 168.442 224.298 1.00 97.33  ? 105 GLN E OE1 1 
ATOM   8738  N NE2 . GLN D 2 89  ? 167.915 170.283 224.539 1.00 91.76  ? 105 GLN E NE2 1 
ATOM   8739  N N   . ASP D 2 90  ? 166.483 166.582 218.613 1.00 76.52  ? 106 ASP E N   1 
ATOM   8740  C CA  . ASP D 2 90  ? 166.138 165.263 218.102 1.00 74.58  ? 106 ASP E CA  1 
ATOM   8741  C C   . ASP D 2 90  ? 166.924 164.875 216.856 1.00 72.14  ? 106 ASP E C   1 
ATOM   8742  O O   . ASP D 2 90  ? 166.646 163.824 216.271 1.00 66.96  ? 106 ASP E O   1 
ATOM   8743  C CB  . ASP D 2 90  ? 164.637 165.192 217.805 1.00 74.85  ? 106 ASP E CB  1 
ATOM   8744  C CG  . ASP D 2 90  ? 163.826 164.762 219.011 1.00 76.91  ? 106 ASP E CG  1 
ATOM   8745  O OD1 . ASP D 2 90  ? 164.421 164.580 220.094 1.00 74.78  ? 106 ASP E OD1 1 
ATOM   8746  O OD2 . ASP D 2 90  ? 162.593 164.609 218.877 1.00 78.23  ? 106 ASP E OD2 1 
ATOM   8747  N N   . VAL D 2 91  ? 167.893 165.686 216.438 1.00 72.42  ? 107 VAL E N   1 
ATOM   8748  C CA  . VAL D 2 91  ? 168.626 165.460 215.199 1.00 62.89  ? 107 VAL E CA  1 
ATOM   8749  C C   . VAL D 2 91  ? 170.119 165.563 215.479 1.00 63.44  ? 107 VAL E C   1 
ATOM   8750  O O   . VAL D 2 91  ? 170.570 166.475 216.180 1.00 66.31  ? 107 VAL E O   1 
ATOM   8751  C CB  . VAL D 2 91  ? 168.197 166.458 214.101 1.00 55.05  ? 107 VAL E CB  1 
ATOM   8752  C CG1 . VAL D 2 91  ? 168.180 167.879 214.641 1.00 55.25  ? 107 VAL E CG1 1 
ATOM   8753  C CG2 . VAL D 2 91  ? 169.099 166.349 212.885 1.00 49.01  ? 107 VAL E CG2 1 
ATOM   8754  N N   . SER D 2 92  ? 170.882 164.614 214.943 1.00 62.73  ? 108 SER E N   1 
ATOM   8755  C CA  . SER D 2 92  ? 172.330 164.632 215.061 1.00 61.35  ? 108 SER E CA  1 
ATOM   8756  C C   . SER D 2 92  ? 172.932 165.675 214.124 1.00 58.84  ? 108 SER E C   1 
ATOM   8757  O O   . SER D 2 92  ? 172.284 166.162 213.194 1.00 59.66  ? 108 SER E O   1 
ATOM   8758  C CB  . SER D 2 92  ? 172.911 163.252 214.754 1.00 61.73  ? 108 SER E CB  1 
ATOM   8759  O OG  . SER D 2 92  ? 174.325 163.295 214.710 1.00 66.15  ? 108 SER E OG  1 
ATOM   8760  N N   . GLU D 2 93  ? 174.195 166.017 214.382 1.00 59.28  ? 109 GLU E N   1 
ATOM   8761  C CA  . GLU D 2 93  ? 174.857 167.047 213.587 1.00 60.05  ? 109 GLU E CA  1 
ATOM   8762  C C   . GLU D 2 93  ? 175.011 166.620 212.132 1.00 57.98  ? 109 GLU E C   1 
ATOM   8763  O O   . GLU D 2 93  ? 174.766 167.414 211.215 1.00 60.06  ? 109 GLU E O   1 
ATOM   8764  C CB  . GLU D 2 93  ? 176.218 167.380 214.196 1.00 64.57  ? 109 GLU E CB  1 
ATOM   8765  C CG  . GLU D 2 93  ? 177.056 168.326 213.359 1.00 65.53  ? 109 GLU E CG  1 
ATOM   8766  C CD  . GLU D 2 93  ? 178.504 168.362 213.801 1.00 72.95  ? 109 GLU E CD  1 
ATOM   8767  O OE1 . GLU D 2 93  ? 178.779 168.018 214.969 1.00 75.82  ? 109 GLU E OE1 1 
ATOM   8768  O OE2 . GLU D 2 93  ? 179.368 168.736 212.980 1.00 75.50  ? 109 GLU E OE2 1 
ATOM   8769  N N   . SER D 2 94  ? 175.416 165.369 211.898 1.00 55.19  ? 110 SER E N   1 
ATOM   8770  C CA  . SER D 2 94  ? 175.600 164.893 210.529 1.00 52.89  ? 110 SER E CA  1 
ATOM   8771  C C   . SER D 2 94  ? 174.277 164.840 209.776 1.00 51.84  ? 110 SER E C   1 
ATOM   8772  O O   . SER D 2 94  ? 174.211 165.208 208.596 1.00 51.50  ? 110 SER E O   1 
ATOM   8773  C CB  . SER D 2 94  ? 176.268 163.520 210.538 1.00 56.95  ? 110 SER E CB  1 
ATOM   8774  O OG  . SER D 2 94  ? 175.560 162.615 211.365 1.00 60.89  ? 110 SER E OG  1 
ATOM   8775  N N   . VAL D 2 95  ? 173.213 164.384 210.439 1.00 50.91  ? 111 VAL E N   1 
ATOM   8776  C CA  . VAL D 2 95  ? 171.907 164.316 209.790 1.00 45.05  ? 111 VAL E CA  1 
ATOM   8777  C C   . VAL D 2 95  ? 171.414 165.713 209.442 1.00 45.32  ? 111 VAL E C   1 
ATOM   8778  O O   . VAL D 2 95  ? 170.843 165.935 208.368 1.00 44.86  ? 111 VAL E O   1 
ATOM   8779  C CB  . VAL D 2 95  ? 170.906 163.561 210.683 1.00 46.26  ? 111 VAL E CB  1 
ATOM   8780  C CG1 . VAL D 2 95  ? 169.518 163.607 210.078 1.00 44.02  ? 111 VAL E CG1 1 
ATOM   8781  C CG2 . VAL D 2 95  ? 171.356 162.125 210.875 1.00 45.91  ? 111 VAL E CG2 1 
ATOM   8782  N N   . PHE D 2 96  ? 171.631 166.680 210.337 1.00 47.06  ? 112 PHE E N   1 
ATOM   8783  C CA  . PHE D 2 96  ? 171.233 168.050 210.033 1.00 45.27  ? 112 PHE E CA  1 
ATOM   8784  C C   . PHE D 2 96  ? 172.065 168.631 208.897 1.00 45.14  ? 112 PHE E C   1 
ATOM   8785  O O   . PHE D 2 96  ? 171.554 169.408 208.086 1.00 46.94  ? 112 PHE E O   1 
ATOM   8786  C CB  . PHE D 2 96  ? 171.335 168.933 211.274 1.00 47.08  ? 112 PHE E CB  1 
ATOM   8787  C CG  . PHE D 2 96  ? 170.534 170.198 211.171 1.00 50.55  ? 112 PHE E CG  1 
ATOM   8788  C CD1 . PHE D 2 96  ? 169.151 170.159 211.180 1.00 47.97  ? 112 PHE E CD1 1 
ATOM   8789  C CD2 . PHE D 2 96  ? 171.162 171.424 211.039 1.00 54.78  ? 112 PHE E CD2 1 
ATOM   8790  C CE1 . PHE D 2 96  ? 168.412 171.318 211.072 1.00 44.71  ? 112 PHE E CE1 1 
ATOM   8791  C CE2 . PHE D 2 96  ? 170.426 172.586 210.933 1.00 51.71  ? 112 PHE E CE2 1 
ATOM   8792  C CZ  . PHE D 2 96  ? 169.050 172.532 210.949 1.00 48.04  ? 112 PHE E CZ  1 
ATOM   8793  N N   . GLN D 2 97  ? 173.348 168.273 208.822 1.00 45.28  ? 113 GLN E N   1 
ATOM   8794  C CA  . GLN D 2 97  ? 174.161 168.712 207.692 1.00 44.18  ? 113 GLN E CA  1 
ATOM   8795  C C   . GLN D 2 97  ? 173.624 168.154 206.379 1.00 42.51  ? 113 GLN E C   1 
ATOM   8796  O O   . GLN D 2 97  ? 173.526 168.878 205.380 1.00 44.16  ? 113 GLN E O   1 
ATOM   8797  C CB  . GLN D 2 97  ? 175.615 168.292 207.898 1.00 47.11  ? 113 GLN E CB  1 
ATOM   8798  C CG  . GLN D 2 97  ? 176.537 168.691 206.763 1.00 49.00  ? 113 GLN E CG  1 
ATOM   8799  C CD  . GLN D 2 97  ? 176.812 170.178 206.735 1.00 56.53  ? 113 GLN E CD  1 
ATOM   8800  O OE1 . GLN D 2 97  ? 177.298 170.748 207.711 1.00 63.36  ? 113 GLN E OE1 1 
ATOM   8801  N NE2 . GLN D 2 97  ? 176.498 170.817 205.615 1.00 53.34  ? 113 GLN E NE2 1 
ATOM   8802  N N   . LEU D 2 98  ? 173.258 166.870 206.368 1.00 38.48  ? 114 LEU E N   1 
ATOM   8803  C CA  . LEU D 2 98  ? 172.671 166.278 205.168 1.00 35.11  ? 114 LEU E CA  1 
ATOM   8804  C C   . LEU D 2 98  ? 171.355 166.952 204.802 1.00 35.50  ? 114 LEU E C   1 
ATOM   8805  O O   . LEU D 2 98  ? 171.080 167.196 203.621 1.00 36.87  ? 114 LEU E O   1 
ATOM   8806  C CB  . LEU D 2 98  ? 172.458 164.776 205.363 1.00 39.69  ? 114 LEU E CB  1 
ATOM   8807  C CG  . LEU D 2 98  ? 173.558 163.816 204.911 1.00 41.21  ? 114 LEU E CG  1 
ATOM   8808  C CD1 . LEU D 2 98  ? 174.508 163.479 206.040 1.00 47.89  ? 114 LEU E CD1 1 
ATOM   8809  C CD2 . LEU D 2 98  ? 172.933 162.554 204.353 1.00 35.78  ? 114 LEU E CD2 1 
ATOM   8810  N N   . LEU D 2 99  ? 170.523 167.249 205.800 1.00 36.91  ? 115 LEU E N   1 
ATOM   8811  C CA  . LEU D 2 99  ? 169.240 167.886 205.525 1.00 33.96  ? 115 LEU E CA  1 
ATOM   8812  C C   . LEU D 2 99  ? 169.423 169.302 204.993 1.00 33.66  ? 115 LEU E C   1 
ATOM   8813  O O   . LEU D 2 99  ? 168.687 169.734 204.101 1.00 34.54  ? 115 LEU E O   1 
ATOM   8814  C CB  . LEU D 2 99  ? 168.377 167.888 206.783 1.00 35.18  ? 115 LEU E CB  1 
ATOM   8815  C CG  . LEU D 2 99  ? 167.289 166.813 206.812 1.00 34.48  ? 115 LEU E CG  1 
ATOM   8816  C CD1 . LEU D 2 99  ? 167.872 165.441 207.100 1.00 30.28  ? 115 LEU E CD1 1 
ATOM   8817  C CD2 . LEU D 2 99  ? 166.235 167.172 207.828 1.00 37.84  ? 115 LEU E CD2 1 
ATOM   8818  N N   . VAL D 2 100 ? 170.396 170.040 205.529 1.00 35.11  ? 116 VAL E N   1 
ATOM   8819  C CA  . VAL D 2 100 ? 170.689 171.378 205.023 1.00 32.97  ? 116 VAL E CA  1 
ATOM   8820  C C   . VAL D 2 100 ? 171.188 171.304 203.586 1.00 32.91  ? 116 VAL E C   1 
ATOM   8821  O O   . VAL D 2 100 ? 170.793 172.108 202.732 1.00 35.75  ? 116 VAL E O   1 
ATOM   8822  C CB  . VAL D 2 100 ? 171.699 172.084 205.946 1.00 37.79  ? 116 VAL E CB  1 
ATOM   8823  C CG1 . VAL D 2 100 ? 172.502 173.121 205.179 1.00 39.11  ? 116 VAL E CG1 1 
ATOM   8824  C CG2 . VAL D 2 100 ? 170.981 172.722 207.120 1.00 40.17  ? 116 VAL E CG2 1 
ATOM   8825  N N   . ASP D 2 101 ? 172.059 170.333 203.294 1.00 32.94  ? 117 ASP E N   1 
ATOM   8826  C CA  . ASP D 2 101 ? 172.530 170.151 201.925 1.00 30.86  ? 117 ASP E CA  1 
ATOM   8827  C C   . ASP D 2 101 ? 171.376 169.842 200.980 1.00 28.33  ? 117 ASP E C   1 
ATOM   8828  O O   . ASP D 2 101 ? 171.325 170.362 199.861 1.00 30.96  ? 117 ASP E O   1 
ATOM   8829  C CB  . ASP D 2 101 ? 173.574 169.037 201.873 1.00 36.63  ? 117 ASP E CB  1 
ATOM   8830  C CG  . ASP D 2 101 ? 174.872 169.423 202.548 1.00 45.46  ? 117 ASP E CG  1 
ATOM   8831  O OD1 . ASP D 2 101 ? 174.934 170.521 203.138 1.00 48.90  ? 117 ASP E OD1 1 
ATOM   8832  O OD2 . ASP D 2 101 ? 175.834 168.629 202.487 1.00 46.75  ? 117 ASP E OD2 1 
ATOM   8833  N N   . TYR D 2 102 ? 170.445 168.988 201.409 1.00 28.74  ? 118 TYR E N   1 
ATOM   8834  C CA  . TYR D 2 102 ? 169.284 168.686 200.578 1.00 25.40  ? 118 TYR E CA  1 
ATOM   8835  C C   . TYR D 2 102 ? 168.414 169.921 200.368 1.00 25.66  ? 118 TYR E C   1 
ATOM   8836  O O   . TYR D 2 102 ? 167.935 170.169 199.257 1.00 26.54  ? 118 TYR E O   1 
ATOM   8837  C CB  . TYR D 2 102 ? 168.467 167.556 201.205 1.00 22.06  ? 118 TYR E CB  1 
ATOM   8838  C CG  . TYR D 2 102 ? 167.139 167.317 200.526 1.00 20.29  ? 118 TYR E CG  1 
ATOM   8839  C CD1 . TYR D 2 102 ? 167.065 166.603 199.341 1.00 20.91  ? 118 TYR E CD1 1 
ATOM   8840  C CD2 . TYR D 2 102 ? 165.960 167.809 201.068 1.00 19.88  ? 118 TYR E CD2 1 
ATOM   8841  C CE1 . TYR D 2 102 ? 165.856 166.385 198.715 1.00 17.71  ? 118 TYR E CE1 1 
ATOM   8842  C CE2 . TYR D 2 102 ? 164.747 167.596 200.447 1.00 17.14  ? 118 TYR E CE2 1 
ATOM   8843  C CZ  . TYR D 2 102 ? 164.703 166.884 199.272 1.00 17.03  ? 118 TYR E CZ  1 
ATOM   8844  O OH  . TYR D 2 102 ? 163.499 166.667 198.651 1.00 24.26  ? 118 TYR E OH  1 
ATOM   8845  N N   . ILE D 2 103 ? 168.195 170.702 201.426 1.00 26.89  ? 119 ILE E N   1 
ATOM   8846  C CA  . ILE D 2 103 ? 167.326 171.871 201.333 1.00 26.15  ? 119 ILE E CA  1 
ATOM   8847  C C   . ILE D 2 103 ? 167.922 172.915 200.397 1.00 28.85  ? 119 ILE E C   1 
ATOM   8848  O O   . ILE D 2 103 ? 167.210 173.523 199.589 1.00 29.67  ? 119 ILE E O   1 
ATOM   8849  C CB  . ILE D 2 103 ? 167.063 172.444 202.738 1.00 26.13  ? 119 ILE E CB  1 
ATOM   8850  C CG1 . ILE D 2 103 ? 165.885 171.724 203.395 1.00 25.36  ? 119 ILE E CG1 1 
ATOM   8851  C CG2 . ILE D 2 103 ? 166.805 173.939 202.680 1.00 27.21  ? 119 ILE E CG2 1 
ATOM   8852  C CD1 . ILE D 2 103 ? 165.652 172.122 204.832 1.00 23.28  ? 119 ILE E CD1 1 
ATOM   8853  N N   . TYR D 2 104 ? 169.234 173.134 200.479 1.00 30.62  ? 120 TYR E N   1 
ATOM   8854  C CA  . TYR D 2 104 ? 169.863 174.196 199.703 1.00 28.83  ? 120 TYR E CA  1 
ATOM   8855  C C   . TYR D 2 104 ? 170.298 173.748 198.312 1.00 30.01  ? 120 TYR E C   1 
ATOM   8856  O O   . TYR D 2 104 ? 170.171 174.517 197.355 1.00 30.84  ? 120 TYR E O   1 
ATOM   8857  C CB  . TYR D 2 104 ? 171.059 174.761 200.469 1.00 30.02  ? 120 TYR E CB  1 
ATOM   8858  C CG  . TYR D 2 104 ? 170.664 175.718 201.568 1.00 33.76  ? 120 TYR E CG  1 
ATOM   8859  C CD1 . TYR D 2 104 ? 170.263 175.251 202.809 1.00 33.43  ? 120 TYR E CD1 1 
ATOM   8860  C CD2 . TYR D 2 104 ? 170.680 177.088 201.359 1.00 34.29  ? 120 TYR E CD2 1 
ATOM   8861  C CE1 . TYR D 2 104 ? 169.896 176.121 203.812 1.00 34.62  ? 120 TYR E CE1 1 
ATOM   8862  C CE2 . TYR D 2 104 ? 170.316 177.964 202.358 1.00 32.42  ? 120 TYR E CE2 1 
ATOM   8863  C CZ  . TYR D 2 104 ? 169.924 177.476 203.581 1.00 34.31  ? 120 TYR E CZ  1 
ATOM   8864  O OH  . TYR D 2 104 ? 169.560 178.346 204.578 1.00 37.94  ? 120 TYR E OH  1 
ATOM   8865  N N   . HIS D 2 105 ? 170.806 172.524 198.169 1.00 31.26  ? 121 HIS E N   1 
ATOM   8866  C CA  . HIS D 2 105 ? 171.279 172.051 196.873 1.00 28.80  ? 121 HIS E CA  1 
ATOM   8867  C C   . HIS D 2 105 ? 170.251 171.215 196.127 1.00 28.45  ? 121 HIS E C   1 
ATOM   8868  O O   . HIS D 2 105 ? 170.242 171.222 194.892 1.00 32.13  ? 121 HIS E O   1 
ATOM   8869  C CB  . HIS D 2 105 ? 172.556 171.223 197.034 1.00 30.05  ? 121 HIS E CB  1 
ATOM   8870  C CG  . HIS D 2 105 ? 173.648 171.925 197.776 1.00 39.35  ? 121 HIS E CG  1 
ATOM   8871  N ND1 . HIS D 2 105 ? 174.730 171.258 198.307 1.00 46.51  ? 121 HIS E ND1 1 
ATOM   8872  C CD2 . HIS D 2 105 ? 173.832 173.234 198.067 1.00 40.99  ? 121 HIS E CD2 1 
ATOM   8873  C CE1 . HIS D 2 105 ? 175.530 172.125 198.901 1.00 49.03  ? 121 HIS E CE1 1 
ATOM   8874  N NE2 . HIS D 2 105 ? 175.009 173.331 198.769 1.00 46.14  ? 121 HIS E NE2 1 
ATOM   8875  N N   . GLY D 2 106 ? 169.395 170.488 196.840 1.00 27.25  ? 122 GLY E N   1 
ATOM   8876  C CA  . GLY D 2 106 ? 168.443 169.598 196.215 1.00 26.90  ? 122 GLY E CA  1 
ATOM   8877  C C   . GLY D 2 106 ? 168.936 168.185 196.003 1.00 28.35  ? 122 GLY E C   1 
ATOM   8878  O O   . GLY D 2 106 ? 168.148 167.328 195.585 1.00 30.07  ? 122 GLY E O   1 
ATOM   8879  N N   . THR D 2 107 ? 170.208 167.912 196.280 1.00 28.26  ? 123 THR E N   1 
ATOM   8880  C CA  . THR D 2 107 ? 170.785 166.586 196.126 1.00 24.69  ? 123 THR E CA  1 
ATOM   8881  C C   . THR D 2 107 ? 171.452 166.174 197.429 1.00 23.93  ? 123 THR E C   1 
ATOM   8882  O O   . THR D 2 107 ? 172.061 166.999 198.115 1.00 25.38  ? 123 THR E O   1 
ATOM   8883  C CB  . THR D 2 107 ? 171.799 166.543 194.971 1.00 29.09  ? 123 THR E CB  1 
ATOM   8884  O OG1 . THR D 2 107 ? 172.436 165.261 194.933 1.00 32.86  ? 123 THR E OG1 1 
ATOM   8885  C CG2 . THR D 2 107 ? 172.851 167.624 195.131 1.00 29.31  ? 123 THR E CG2 1 
ATOM   8886  N N   . VAL D 2 108 ? 171.319 164.892 197.771 1.00 30.47  ? 124 VAL E N   1 
ATOM   8887  C CA  . VAL D 2 108 ? 171.869 164.339 199.001 1.00 26.80  ? 124 VAL E CA  1 
ATOM   8888  C C   . VAL D 2 108 ? 172.425 162.952 198.703 1.00 25.51  ? 124 VAL E C   1 
ATOM   8889  O O   . VAL D 2 108 ? 172.040 162.298 197.732 1.00 29.40  ? 124 VAL E O   1 
ATOM   8890  C CB  . VAL D 2 108 ? 170.809 164.281 200.127 1.00 26.25  ? 124 VAL E CB  1 
ATOM   8891  C CG1 . VAL D 2 108 ? 169.868 163.105 199.927 1.00 25.45  ? 124 VAL E CG1 1 
ATOM   8892  C CG2 . VAL D 2 108 ? 171.470 164.228 201.491 1.00 29.24  ? 124 VAL E CG2 1 
ATOM   8893  N N   . LYS D 2 109 ? 173.354 162.511 199.549 1.00 25.23  ? 125 LYS E N   1 
ATOM   8894  C CA  . LYS D 2 109 ? 173.998 161.208 199.417 1.00 26.07  ? 125 LYS E CA  1 
ATOM   8895  C C   . LYS D 2 109 ? 173.479 160.300 200.526 1.00 26.69  ? 125 LYS E C   1 
ATOM   8896  O O   . LYS D 2 109 ? 173.820 160.486 201.699 1.00 27.18  ? 125 LYS E O   1 
ATOM   8897  C CB  . LYS D 2 109 ? 175.517 161.343 199.479 1.00 29.06  ? 125 LYS E CB  1 
ATOM   8898  C CG  . LYS D 2 109 ? 176.266 160.049 199.228 1.00 33.34  ? 125 LYS E CG  1 
ATOM   8899  C CD  . LYS D 2 109 ? 177.259 160.200 198.088 1.00 35.08  ? 125 LYS E CD  1 
ATOM   8900  C CE  . LYS D 2 109 ? 177.512 158.871 197.397 1.00 41.15  ? 125 LYS E CE  1 
ATOM   8901  N NZ  . LYS D 2 109 ? 177.528 157.739 198.362 1.00 40.76  ? 125 LYS E NZ  1 
ATOM   8902  N N   . LEU D 2 110 ? 172.667 159.315 200.152 1.00 27.87  ? 126 LEU E N   1 
ATOM   8903  C CA  . LEU D 2 110 ? 171.994 158.454 201.113 1.00 27.73  ? 126 LEU E CA  1 
ATOM   8904  C C   . LEU D 2 110 ? 172.837 157.228 201.429 1.00 30.12  ? 126 LEU E C   1 
ATOM   8905  O O   . LEU D 2 110 ? 173.400 156.598 200.532 1.00 33.08  ? 126 LEU E O   1 
ATOM   8906  C CB  . LEU D 2 110 ? 170.629 158.022 200.577 1.00 24.28  ? 126 LEU E CB  1 
ATOM   8907  C CG  . LEU D 2 110 ? 169.616 159.138 200.331 1.00 23.22  ? 126 LEU E CG  1 
ATOM   8908  C CD1 . LEU D 2 110 ? 168.389 158.597 199.628 1.00 23.48  ? 126 LEU E CD1 1 
ATOM   8909  C CD2 . LEU D 2 110 ? 169.233 159.805 201.637 1.00 19.68  ? 126 LEU E CD2 1 
ATOM   8910  N N   . ARG D 2 111 ? 172.916 156.892 202.715 1.00 29.95  ? 127 ARG E N   1 
ATOM   8911  C CA  . ARG D 2 111 ? 173.676 155.747 203.188 1.00 28.37  ? 127 ARG E CA  1 
ATOM   8912  C C   . ARG D 2 111 ? 172.812 154.914 204.121 1.00 30.88  ? 127 ARG E C   1 
ATOM   8913  O O   . ARG D 2 111 ? 171.926 155.435 204.802 1.00 32.27  ? 127 ARG E O   1 
ATOM   8914  C CB  . ARG D 2 111 ? 174.952 156.179 203.914 1.00 36.25  ? 127 ARG E CB  1 
ATOM   8915  C CG  . ARG D 2 111 ? 176.122 156.471 202.994 1.00 39.18  ? 127 ARG E CG  1 
ATOM   8916  C CD  . ARG D 2 111 ? 176.814 157.766 203.378 1.00 41.98  ? 127 ARG E CD  1 
ATOM   8917  N NE  . ARG D 2 111 ? 176.871 157.943 204.823 1.00 49.10  ? 127 ARG E NE  1 
ATOM   8918  C CZ  . ARG D 2 111 ? 177.742 157.338 205.619 1.00 51.07  ? 127 ARG E CZ  1 
ATOM   8919  N NH1 . ARG D 2 111 ? 178.651 156.504 205.141 1.00 50.21  ? 127 ARG E NH1 1 
ATOM   8920  N NH2 . ARG D 2 111 ? 177.700 157.576 206.926 1.00 51.73  ? 127 ARG E NH2 1 
ATOM   8921  N N   . ALA D 2 112 ? 173.081 153.608 204.148 1.00 34.64  ? 128 ALA E N   1 
ATOM   8922  C CA  . ALA D 2 112 ? 172.282 152.691 204.949 1.00 31.80  ? 128 ALA E CA  1 
ATOM   8923  C C   . ALA D 2 112 ? 172.578 152.789 206.439 1.00 36.01  ? 128 ALA E C   1 
ATOM   8924  O O   . ALA D 2 112 ? 171.768 152.324 207.247 1.00 34.26  ? 128 ALA E O   1 
ATOM   8925  C CB  . ALA D 2 112 ? 172.502 151.254 204.475 1.00 26.17  ? 128 ALA E CB  1 
ATOM   8926  N N   . GLU D 2 113 ? 173.713 153.376 206.821 1.00 38.20  ? 129 GLU E N   1 
ATOM   8927  C CA  . GLU D 2 113 ? 174.044 153.504 208.236 1.00 40.17  ? 129 GLU E CA  1 
ATOM   8928  C C   . GLU D 2 113 ? 173.255 154.615 208.917 1.00 41.82  ? 129 GLU E C   1 
ATOM   8929  O O   . GLU D 2 113 ? 172.970 154.518 210.116 1.00 40.72  ? 129 GLU E O   1 
ATOM   8930  C CB  . GLU D 2 113 ? 175.545 153.742 208.404 1.00 44.75  ? 129 GLU E CB  1 
ATOM   8931  C CG  . GLU D 2 113 ? 176.409 152.736 207.663 1.00 50.65  ? 129 GLU E CG  1 
ATOM   8932  C CD  . GLU D 2 113 ? 177.176 153.358 206.516 1.00 58.29  ? 129 GLU E CD  1 
ATOM   8933  O OE1 . GLU D 2 113 ? 177.646 154.504 206.670 1.00 57.82  ? 129 GLU E OE1 1 
ATOM   8934  O OE2 . GLU D 2 113 ? 177.306 152.704 205.460 1.00 60.32  ? 129 GLU E OE2 1 
ATOM   8935  N N   . GLU D 2 114 ? 172.903 155.671 208.184 1.00 39.75  ? 130 GLU E N   1 
ATOM   8936  C CA  . GLU D 2 114 ? 172.124 156.779 208.721 1.00 35.96  ? 130 GLU E CA  1 
ATOM   8937  C C   . GLU D 2 114 ? 170.693 156.792 208.202 1.00 35.15  ? 130 GLU E C   1 
ATOM   8938  O O   . GLU D 2 114 ? 170.014 157.815 208.320 1.00 40.03  ? 130 GLU E O   1 
ATOM   8939  C CB  . GLU D 2 114 ? 172.801 158.110 208.391 1.00 41.30  ? 130 GLU E CB  1 
ATOM   8940  C CG  . GLU D 2 114 ? 174.302 158.120 208.594 1.00 51.08  ? 130 GLU E CG  1 
ATOM   8941  C CD  . GLU D 2 114 ? 174.950 159.383 208.060 1.00 61.70  ? 130 GLU E CD  1 
ATOM   8942  O OE1 . GLU D 2 114 ? 174.328 160.059 207.215 1.00 58.16  ? 130 GLU E OE1 1 
ATOM   8943  O OE2 . GLU D 2 114 ? 176.081 159.699 208.485 1.00 65.03  ? 130 GLU E OE2 1 
ATOM   8944  N N   . LEU D 2 115 ? 170.218 155.681 207.637 1.00 32.63  ? 131 LEU E N   1 
ATOM   8945  C CA  . LEU D 2 115 ? 168.949 155.691 206.916 1.00 28.82  ? 131 LEU E CA  1 
ATOM   8946  C C   . LEU D 2 115 ? 167.766 155.951 207.841 1.00 28.78  ? 131 LEU E C   1 
ATOM   8947  O O   . LEU D 2 115 ? 166.883 156.751 207.513 1.00 30.87  ? 131 LEU E O   1 
ATOM   8948  C CB  . LEU D 2 115 ? 168.769 154.368 206.177 1.00 28.93  ? 131 LEU E CB  1 
ATOM   8949  C CG  . LEU D 2 115 ? 167.790 154.358 205.008 1.00 25.11  ? 131 LEU E CG  1 
ATOM   8950  C CD1 . LEU D 2 115 ? 167.978 155.591 204.147 1.00 22.77  ? 131 LEU E CD1 1 
ATOM   8951  C CD2 . LEU D 2 115 ? 167.981 153.094 204.201 1.00 20.58  ? 131 LEU E CD2 1 
ATOM   8952  N N   . GLN D 2 116 ? 167.721 155.281 208.994 1.00 28.61  ? 132 GLN E N   1 
ATOM   8953  C CA  . GLN D 2 116 ? 166.573 155.428 209.886 1.00 31.09  ? 132 GLN E CA  1 
ATOM   8954  C C   . GLN D 2 116 ? 166.509 156.826 210.488 1.00 36.22  ? 132 GLN E C   1 
ATOM   8955  O O   . GLN D 2 116 ? 165.420 157.392 210.643 1.00 40.72  ? 132 GLN E O   1 
ATOM   8956  C CB  . GLN D 2 116 ? 166.623 154.371 210.986 1.00 36.39  ? 132 GLN E CB  1 
ATOM   8957  C CG  . GLN D 2 116 ? 165.686 153.200 210.759 1.00 42.04  ? 132 GLN E CG  1 
ATOM   8958  C CD  . GLN D 2 116 ? 166.158 151.934 211.441 1.00 47.43  ? 132 GLN E CD  1 
ATOM   8959  O OE1 . GLN D 2 116 ? 166.382 151.915 212.650 1.00 47.60  ? 132 GLN E OE1 1 
ATOM   8960  N NE2 . GLN D 2 116 ? 166.310 150.866 210.668 1.00 45.54  ? 132 GLN E NE2 1 
ATOM   8961  N N   . GLU D 2 117 ? 167.663 157.395 210.842 1.00 37.06  ? 133 GLU E N   1 
ATOM   8962  C CA  . GLU D 2 117 ? 167.686 158.748 211.386 1.00 36.14  ? 133 GLU E CA  1 
ATOM   8963  C C   . GLU D 2 117 ? 167.170 159.756 210.368 1.00 35.31  ? 133 GLU E C   1 
ATOM   8964  O O   . GLU D 2 117 ? 166.346 160.619 210.693 1.00 39.63  ? 133 GLU E O   1 
ATOM   8965  C CB  . GLU D 2 117 ? 169.103 159.108 211.829 1.00 39.71  ? 133 GLU E CB  1 
ATOM   8966  C CG  . GLU D 2 117 ? 169.302 159.125 213.335 1.00 52.65  ? 133 GLU E CG  1 
ATOM   8967  C CD  . GLU D 2 117 ? 168.940 160.460 213.957 1.00 59.79  ? 133 GLU E CD  1 
ATOM   8968  O OE1 . GLU D 2 117 ? 168.686 161.420 213.202 1.00 58.16  ? 133 GLU E OE1 1 
ATOM   8969  O OE2 . GLU D 2 117 ? 168.913 160.550 215.202 1.00 64.74  ? 133 GLU E OE2 1 
ATOM   8970  N N   . ILE D 2 118 ? 167.643 159.658 209.124 1.00 32.85  ? 134 ILE E N   1 
ATOM   8971  C CA  . ILE D 2 118 ? 167.192 160.575 208.082 1.00 29.76  ? 134 ILE E CA  1 
ATOM   8972  C C   . ILE D 2 118 ? 165.708 160.380 207.814 1.00 32.04  ? 134 ILE E C   1 
ATOM   8973  O O   . ILE D 2 118 ? 164.971 161.346 207.598 1.00 35.40  ? 134 ILE E O   1 
ATOM   8974  C CB  . ILE D 2 118 ? 168.030 160.391 206.804 1.00 29.18  ? 134 ILE E CB  1 
ATOM   8975  C CG1 . ILE D 2 118 ? 169.504 160.671 207.085 1.00 34.12  ? 134 ILE E CG1 1 
ATOM   8976  C CG2 . ILE D 2 118 ? 167.536 161.307 205.706 1.00 26.54  ? 134 ILE E CG2 1 
ATOM   8977  C CD1 . ILE D 2 118 ? 170.430 160.168 206.003 1.00 35.00  ? 134 ILE E CD1 1 
ATOM   8978  N N   . TYR D 2 119 ? 165.247 159.128 207.832 1.00 33.41  ? 135 TYR E N   1 
ATOM   8979  C CA  . TYR D 2 119 ? 163.828 158.837 207.646 1.00 33.13  ? 135 TYR E CA  1 
ATOM   8980  C C   . TYR D 2 119 ? 162.983 159.534 208.709 1.00 32.78  ? 135 TYR E C   1 
ATOM   8981  O O   . TYR D 2 119 ? 162.020 160.249 208.393 1.00 33.91  ? 135 TYR E O   1 
ATOM   8982  C CB  . TYR D 2 119 ? 163.632 157.318 207.681 1.00 32.05  ? 135 TYR E CB  1 
ATOM   8983  C CG  . TYR D 2 119 ? 162.211 156.818 207.571 1.00 33.88  ? 135 TYR E CG  1 
ATOM   8984  C CD1 . TYR D 2 119 ? 161.575 156.740 206.342 1.00 32.04  ? 135 TYR E CD1 1 
ATOM   8985  C CD2 . TYR D 2 119 ? 161.518 156.391 208.694 1.00 33.46  ? 135 TYR E CD2 1 
ATOM   8986  C CE1 . TYR D 2 119 ? 160.283 156.270 206.237 1.00 29.71  ? 135 TYR E CE1 1 
ATOM   8987  C CE2 . TYR D 2 119 ? 160.224 155.923 208.599 1.00 34.50  ? 135 TYR E CE2 1 
ATOM   8988  C CZ  . TYR D 2 119 ? 159.612 155.865 207.368 1.00 33.73  ? 135 TYR E CZ  1 
ATOM   8989  O OH  . TYR D 2 119 ? 158.324 155.397 207.267 1.00 40.83  ? 135 TYR E OH  1 
ATOM   8990  N N   . GLU D 2 120 ? 163.355 159.363 209.980 1.00 32.81  ? 136 GLU E N   1 
ATOM   8991  C CA  . GLU D 2 120 ? 162.596 159.964 211.072 1.00 34.79  ? 136 GLU E CA  1 
ATOM   8992  C C   . GLU D 2 120 ? 162.626 161.486 211.008 1.00 36.52  ? 136 GLU E C   1 
ATOM   8993  O O   . GLU D 2 120 ? 161.592 162.141 211.182 1.00 39.52  ? 136 GLU E O   1 
ATOM   8994  C CB  . GLU D 2 120 ? 163.142 159.482 212.414 1.00 39.40  ? 136 GLU E CB  1 
ATOM   8995  C CG  . GLU D 2 120 ? 162.813 158.041 212.749 1.00 46.36  ? 136 GLU E CG  1 
ATOM   8996  C CD  . GLU D 2 120 ? 163.802 157.436 213.723 1.00 53.57  ? 136 GLU E CD  1 
ATOM   8997  O OE1 . GLU D 2 120 ? 164.424 158.201 214.489 1.00 55.85  ? 136 GLU E OE1 1 
ATOM   8998  O OE2 . GLU D 2 120 ? 163.958 156.198 213.725 1.00 53.32  ? 136 GLU E OE2 1 
ATOM   8999  N N   . VAL D 2 121 ? 163.802 162.069 210.767 1.00 38.18  ? 137 VAL E N   1 
ATOM   9000  C CA  . VAL D 2 121 ? 163.913 163.525 210.769 1.00 32.62  ? 137 VAL E CA  1 
ATOM   9001  C C   . VAL D 2 121 ? 163.186 164.127 209.570 1.00 30.63  ? 137 VAL E C   1 
ATOM   9002  O O   . VAL D 2 121 ? 162.590 165.204 209.671 1.00 35.73  ? 137 VAL E O   1 
ATOM   9003  C CB  . VAL D 2 121 ? 165.391 163.951 210.823 1.00 34.54  ? 137 VAL E CB  1 
ATOM   9004  C CG1 . VAL D 2 121 ? 165.503 165.454 210.844 1.00 37.23  ? 137 VAL E CG1 1 
ATOM   9005  C CG2 . VAL D 2 121 ? 166.053 163.381 212.059 1.00 38.14  ? 137 VAL E CG2 1 
ATOM   9006  N N   . SER D 2 122 ? 163.219 163.451 208.419 1.00 31.17  ? 138 SER E N   1 
ATOM   9007  C CA  . SER D 2 122 ? 162.481 163.931 207.258 1.00 29.67  ? 138 SER E CA  1 
ATOM   9008  C C   . SER D 2 122 ? 160.979 163.849 207.488 1.00 34.48  ? 138 SER E C   1 
ATOM   9009  O O   . SER D 2 122 ? 160.226 164.705 207.012 1.00 35.48  ? 138 SER E O   1 
ATOM   9010  C CB  . SER D 2 122 ? 162.876 163.132 206.019 1.00 27.18  ? 138 SER E CB  1 
ATOM   9011  O OG  . SER D 2 122 ? 164.278 162.960 205.954 1.00 32.08  ? 138 SER E OG  1 
ATOM   9012  N N   . ASP D 2 123 ? 160.518 162.817 208.198 1.00 40.29  ? 139 ASP E N   1 
ATOM   9013  C CA  . ASP D 2 123 ? 159.107 162.774 208.572 1.00 36.95  ? 139 ASP E CA  1 
ATOM   9014  C C   . ASP D 2 123 ? 158.760 163.907 209.529 1.00 36.68  ? 139 ASP E C   1 
ATOM   9015  O O   . ASP D 2 123 ? 157.689 164.516 209.421 1.00 40.43  ? 139 ASP E O   1 
ATOM   9016  C CB  . ASP D 2 123 ? 158.765 161.422 209.195 1.00 40.10  ? 139 ASP E CB  1 
ATOM   9017  C CG  . ASP D 2 123 ? 157.278 161.254 209.438 1.00 48.40  ? 139 ASP E CG  1 
ATOM   9018  O OD1 . ASP D 2 123 ? 156.492 161.428 208.484 1.00 45.36  ? 139 ASP E OD1 1 
ATOM   9019  O OD2 . ASP D 2 123 ? 156.894 160.945 210.585 1.00 58.88  ? 139 ASP E OD2 1 
ATOM   9020  N N   . MET D 2 124 ? 159.654 164.201 210.475 1.00 37.20  ? 140 MET E N   1 
ATOM   9021  C CA  . MET D 2 124 ? 159.374 165.236 211.467 1.00 38.89  ? 140 MET E CA  1 
ATOM   9022  C C   . MET D 2 124 ? 159.360 166.628 210.846 1.00 37.68  ? 140 MET E C   1 
ATOM   9023  O O   . MET D 2 124 ? 158.523 167.463 211.205 1.00 41.13  ? 140 MET E O   1 
ATOM   9024  C CB  . MET D 2 124 ? 160.401 165.166 212.597 1.00 40.13  ? 140 MET E CB  1 
ATOM   9025  C CG  . MET D 2 124 ? 160.411 166.377 213.506 1.00 40.83  ? 140 MET E CG  1 
ATOM   9026  S SD  . MET D 2 124 ? 161.180 166.034 215.097 1.00 76.29  ? 140 MET E SD  1 
ATOM   9027  C CE  . MET D 2 124 ? 162.796 165.470 214.575 1.00 56.64  ? 140 MET E CE  1 
ATOM   9028  N N   . TYR D 2 125 ? 160.268 166.896 209.912 1.00 37.19  ? 141 TYR E N   1 
ATOM   9029  C CA  . TYR D 2 125 ? 160.437 168.225 209.339 1.00 31.73  ? 141 TYR E CA  1 
ATOM   9030  C C   . TYR D 2 125 ? 159.589 168.454 208.097 1.00 30.23  ? 141 TYR E C   1 
ATOM   9031  O O   . TYR D 2 125 ? 159.753 169.483 207.439 1.00 33.76  ? 141 TYR E O   1 
ATOM   9032  C CB  . TYR D 2 125 ? 161.910 168.476 209.003 1.00 29.39  ? 141 TYR E CB  1 
ATOM   9033  C CG  . TYR D 2 125 ? 162.807 168.667 210.206 1.00 32.50  ? 141 TYR E CG  1 
ATOM   9034  C CD1 . TYR D 2 125 ? 162.291 168.665 211.492 1.00 37.57  ? 141 TYR E CD1 1 
ATOM   9035  C CD2 . TYR D 2 125 ? 164.170 168.846 210.053 1.00 32.21  ? 141 TYR E CD2 1 
ATOM   9036  C CE1 . TYR D 2 125 ? 163.108 168.835 212.588 1.00 37.53  ? 141 TYR E CE1 1 
ATOM   9037  C CE2 . TYR D 2 125 ? 164.993 169.017 211.143 1.00 37.16  ? 141 TYR E CE2 1 
ATOM   9038  C CZ  . TYR D 2 125 ? 164.457 169.010 212.407 1.00 40.52  ? 141 TYR E CZ  1 
ATOM   9039  O OH  . TYR D 2 125 ? 165.274 169.181 213.499 1.00 48.92  ? 141 TYR E OH  1 
ATOM   9040  N N   . GLN D 2 126 ? 158.701 167.519 207.756 1.00 31.69  ? 142 GLN E N   1 
ATOM   9041  C CA  . GLN D 2 126 ? 157.805 167.651 206.604 1.00 32.86  ? 142 GLN E CA  1 
ATOM   9042  C C   . GLN D 2 126 ? 158.581 167.777 205.296 1.00 30.05  ? 142 GLN E C   1 
ATOM   9043  O O   . GLN D 2 126 ? 158.211 168.543 204.405 1.00 32.02  ? 142 GLN E O   1 
ATOM   9044  C CB  . GLN D 2 126 ? 156.845 168.830 206.778 1.00 38.66  ? 142 GLN E CB  1 
ATOM   9045  C CG  . GLN D 2 126 ? 155.432 168.435 207.169 1.00 39.31  ? 142 GLN E CG  1 
ATOM   9046  C CD  . GLN D 2 126 ? 155.307 168.113 208.642 1.00 43.31  ? 142 GLN E CD  1 
ATOM   9047  O OE1 . GLN D 2 126 ? 155.153 169.006 209.474 1.00 43.00  ? 142 GLN E OE1 1 
ATOM   9048  N NE2 . GLN D 2 126 ? 155.374 166.829 208.974 1.00 41.91  ? 142 GLN E NE2 1 
ATOM   9049  N N   . LEU D 2 127 ? 159.669 167.018 205.178 1.00 28.46  ? 143 LEU E N   1 
ATOM   9050  C CA  . LEU D 2 127 ? 160.450 166.939 203.943 1.00 25.83  ? 143 LEU E CA  1 
ATOM   9051  C C   . LEU D 2 127 ? 159.915 165.752 203.153 1.00 26.28  ? 143 LEU E C   1 
ATOM   9052  O O   . LEU D 2 127 ? 160.394 164.627 203.280 1.00 34.76  ? 143 LEU E O   1 
ATOM   9053  C CB  . LEU D 2 127 ? 161.934 166.800 204.253 1.00 26.46  ? 143 LEU E CB  1 
ATOM   9054  C CG  . LEU D 2 127 ? 162.806 168.057 204.199 1.00 25.61  ? 143 LEU E CG  1 
ATOM   9055  C CD1 . LEU D 2 127 ? 162.119 169.235 204.858 1.00 25.50  ? 143 LEU E CD1 1 
ATOM   9056  C CD2 . LEU D 2 127 ? 164.142 167.792 204.866 1.00 24.19  ? 143 LEU E CD2 1 
ATOM   9057  N N   . THR D 2 128 ? 158.909 166.014 202.316 1.00 25.42  ? 144 THR E N   1 
ATOM   9058  C CA  . THR D 2 128 ? 158.094 164.938 201.757 1.00 25.87  ? 144 THR E CA  1 
ATOM   9059  C C   . THR D 2 128 ? 158.878 164.076 200.771 1.00 28.31  ? 144 THR E C   1 
ATOM   9060  O O   . THR D 2 128 ? 158.844 162.843 200.852 1.00 31.26  ? 144 THR E O   1 
ATOM   9061  C CB  . THR D 2 128 ? 156.851 165.527 201.090 1.00 30.44  ? 144 THR E CB  1 
ATOM   9062  O OG1 . THR D 2 128 ? 155.928 165.958 202.096 1.00 29.87  ? 144 THR E OG1 1 
ATOM   9063  C CG2 . THR D 2 128 ? 156.175 164.495 200.207 1.00 31.91  ? 144 THR E CG2 1 
ATOM   9064  N N   . SER D 2 129 ? 159.582 164.702 199.825 1.00 29.42  ? 145 SER E N   1 
ATOM   9065  C CA  . SER D 2 129 ? 160.281 163.933 198.797 1.00 27.81  ? 145 SER E CA  1 
ATOM   9066  C C   . SER D 2 129 ? 161.448 163.147 199.382 1.00 25.99  ? 145 SER E C   1 
ATOM   9067  O O   . SER D 2 129 ? 161.669 161.983 199.019 1.00 29.55  ? 145 SER E O   1 
ATOM   9068  C CB  . SER D 2 129 ? 160.761 164.864 197.687 1.00 29.95  ? 145 SER E CB  1 
ATOM   9069  O OG  . SER D 2 129 ? 159.694 165.213 196.825 1.00 35.16  ? 145 SER E OG  1 
ATOM   9070  N N   . LEU D 2 130 ? 162.208 163.767 200.286 1.00 24.36  ? 146 LEU E N   1 
ATOM   9071  C CA  . LEU D 2 130 ? 163.273 163.048 200.972 1.00 21.88  ? 146 LEU E CA  1 
ATOM   9072  C C   . LEU D 2 130 ? 162.709 161.896 201.790 1.00 25.92  ? 146 LEU E C   1 
ATOM   9073  O O   . LEU D 2 130 ? 163.295 160.810 201.831 1.00 27.84  ? 146 LEU E O   1 
ATOM   9074  C CB  . LEU D 2 130 ? 164.065 164.004 201.862 1.00 18.51  ? 146 LEU E CB  1 
ATOM   9075  C CG  . LEU D 2 130 ? 165.368 163.470 202.458 1.00 16.89  ? 146 LEU E CG  1 
ATOM   9076  C CD1 . LEU D 2 130 ? 166.286 162.949 201.371 1.00 17.50  ? 146 LEU E CD1 1 
ATOM   9077  C CD2 . LEU D 2 130 ? 166.061 164.536 203.282 1.00 17.12  ? 146 LEU E CD2 1 
ATOM   9078  N N   . PHE D 2 131 ? 161.569 162.116 202.448 1.00 25.58  ? 147 PHE E N   1 
ATOM   9079  C CA  . PHE D 2 131 ? 160.935 161.055 203.223 1.00 25.68  ? 147 PHE E CA  1 
ATOM   9080  C C   . PHE D 2 131 ? 160.525 159.890 202.332 1.00 27.13  ? 147 PHE E C   1 
ATOM   9081  O O   . PHE D 2 131 ? 160.722 158.725 202.692 1.00 30.88  ? 147 PHE E O   1 
ATOM   9082  C CB  . PHE D 2 131 ? 159.727 161.618 203.971 1.00 29.72  ? 147 PHE E CB  1 
ATOM   9083  C CG  . PHE D 2 131 ? 158.908 160.583 204.683 1.00 32.85  ? 147 PHE E CG  1 
ATOM   9084  C CD1 . PHE D 2 131 ? 159.316 160.075 205.901 1.00 32.33  ? 147 PHE E CD1 1 
ATOM   9085  C CD2 . PHE D 2 131 ? 157.716 160.135 204.143 1.00 30.39  ? 147 PHE E CD2 1 
ATOM   9086  C CE1 . PHE D 2 131 ? 158.559 159.133 206.560 1.00 32.43  ? 147 PHE E CE1 1 
ATOM   9087  C CE2 . PHE D 2 131 ? 156.957 159.191 204.798 1.00 30.01  ? 147 PHE E CE2 1 
ATOM   9088  C CZ  . PHE D 2 131 ? 157.380 158.691 206.007 1.00 33.14  ? 147 PHE E CZ  1 
ATOM   9089  N N   . GLU D 2 132 ? 159.957 160.183 201.161 1.00 26.57  ? 148 GLU E N   1 
ATOM   9090  C CA  . GLU D 2 132 ? 159.556 159.118 200.247 1.00 25.21  ? 148 GLU E CA  1 
ATOM   9091  C C   . GLU D 2 132 ? 160.760 158.340 199.732 1.00 24.72  ? 148 GLU E C   1 
ATOM   9092  O O   . GLU D 2 132 ? 160.721 157.105 199.654 1.00 28.79  ? 148 GLU E O   1 
ATOM   9093  C CB  . GLU D 2 132 ? 158.758 159.701 199.082 1.00 29.47  ? 148 GLU E CB  1 
ATOM   9094  C CG  . GLU D 2 132 ? 157.402 160.254 199.479 1.00 35.12  ? 148 GLU E CG  1 
ATOM   9095  C CD  . GLU D 2 132 ? 156.689 160.923 198.324 1.00 43.60  ? 148 GLU E CD  1 
ATOM   9096  O OE1 . GLU D 2 132 ? 157.063 160.662 197.162 1.00 46.39  ? 148 GLU E OE1 1 
ATOM   9097  O OE2 . GLU D 2 132 ? 155.752 161.707 198.577 1.00 41.91  ? 148 GLU E OE2 1 
ATOM   9098  N N   . GLU D 2 133 ? 161.837 159.040 199.370 1.00 25.29  ? 149 GLU E N   1 
ATOM   9099  C CA  . GLU D 2 133 ? 163.029 158.344 198.893 1.00 23.39  ? 149 GLU E CA  1 
ATOM   9100  C C   . GLU D 2 133 ? 163.652 157.494 199.994 1.00 24.04  ? 149 GLU E C   1 
ATOM   9101  O O   . GLU D 2 133 ? 164.095 156.366 199.743 1.00 24.85  ? 149 GLU E O   1 
ATOM   9102  C CB  . GLU D 2 133 ? 164.045 159.343 198.348 1.00 25.33  ? 149 GLU E CB  1 
ATOM   9103  C CG  . GLU D 2 133 ? 165.259 158.688 197.714 1.00 27.44  ? 149 GLU E CG  1 
ATOM   9104  C CD  . GLU D 2 133 ? 164.890 157.684 196.637 1.00 32.37  ? 149 GLU E CD  1 
ATOM   9105  O OE1 . GLU D 2 133 ? 164.014 157.994 195.803 1.00 32.54  ? 149 GLU E OE1 1 
ATOM   9106  O OE2 . GLU D 2 133 ? 165.477 156.582 196.624 1.00 30.94  ? 149 GLU E OE2 1 
ATOM   9107  N N   . CYS D 2 134 ? 163.698 158.018 201.220 1.00 26.30  ? 150 CYS E N   1 
ATOM   9108  C CA  . CYS D 2 134 ? 164.217 157.241 202.339 1.00 21.80  ? 150 CYS E CA  1 
ATOM   9109  C C   . CYS D 2 134 ? 163.346 156.025 202.614 1.00 22.78  ? 150 CYS E C   1 
ATOM   9110  O O   . CYS D 2 134 ? 163.856 154.962 202.973 1.00 25.34  ? 150 CYS E O   1 
ATOM   9111  C CB  . CYS D 2 134 ? 164.324 158.119 203.584 1.00 23.36  ? 150 CYS E CB  1 
ATOM   9112  S SG  . CYS D 2 134 ? 165.546 159.435 203.463 1.00 26.98  ? 150 CYS E SG  1 
ATOM   9113  N N   . SER D 2 135 ? 162.028 156.162 202.460 1.00 22.90  ? 151 SER E N   1 
ATOM   9114  C CA  . SER D 2 135 ? 161.137 155.022 202.653 1.00 23.20  ? 151 SER E CA  1 
ATOM   9115  C C   . SER D 2 135 ? 161.363 153.954 201.590 1.00 21.19  ? 151 SER E C   1 
ATOM   9116  O O   . SER D 2 135 ? 161.345 152.756 201.894 1.00 21.27  ? 151 SER E O   1 
ATOM   9117  C CB  . SER D 2 135 ? 159.684 155.490 202.648 1.00 29.13  ? 151 SER E CB  1 
ATOM   9118  O OG  . SER D 2 135 ? 158.816 154.456 202.223 1.00 34.91  ? 151 SER E OG  1 
ATOM   9119  N N   . ARG D 2 136 ? 161.574 154.368 200.338 1.00 22.50  ? 152 ARG E N   1 
ATOM   9120  C CA  . ARG D 2 136 ? 161.878 153.402 199.284 1.00 18.50  ? 152 ARG E CA  1 
ATOM   9121  C C   . ARG D 2 136 ? 163.203 152.695 199.544 1.00 18.66  ? 152 ARG E C   1 
ATOM   9122  O O   . ARG D 2 136 ? 163.314 151.478 199.356 1.00 19.58  ? 152 ARG E O   1 
ATOM   9123  C CB  . ARG D 2 136 ? 161.899 154.095 197.925 1.00 17.67  ? 152 ARG E CB  1 
ATOM   9124  C CG  . ARG D 2 136 ? 160.541 154.560 197.455 1.00 19.06  ? 152 ARG E CG  1 
ATOM   9125  C CD  . ARG D 2 136 ? 160.568 154.930 195.989 1.00 23.30  ? 152 ARG E CD  1 
ATOM   9126  N NE  . ARG D 2 136 ? 161.184 156.232 195.774 1.00 28.30  ? 152 ARG E NE  1 
ATOM   9127  C CZ  . ARG D 2 136 ? 160.510 157.346 195.529 1.00 30.05  ? 152 ARG E CZ  1 
ATOM   9128  N NH1 . ARG D 2 136 ? 159.189 157.354 195.462 1.00 27.17  ? 152 ARG E NH1 1 
ATOM   9129  N NH2 . ARG D 2 136 ? 161.178 158.482 195.348 1.00 30.65  ? 152 ARG E NH2 1 
ATOM   9130  N N   . PHE D 2 137 ? 164.221 153.445 199.972 1.00 20.03  ? 153 PHE E N   1 
ATOM   9131  C CA  . PHE D 2 137 ? 165.501 152.839 200.328 1.00 15.61  ? 153 PHE E CA  1 
ATOM   9132  C C   . PHE D 2 137 ? 165.339 151.863 201.489 1.00 16.16  ? 153 PHE E C   1 
ATOM   9133  O O   . PHE D 2 137 ? 165.898 150.762 201.470 1.00 19.81  ? 153 PHE E O   1 
ATOM   9134  C CB  . PHE D 2 137 ? 166.504 153.946 200.672 1.00 20.74  ? 153 PHE E CB  1 
ATOM   9135  C CG  . PHE D 2 137 ? 167.946 153.494 200.744 1.00 23.87  ? 153 PHE E CG  1 
ATOM   9136  C CD1 . PHE D 2 137 ? 168.311 152.183 200.500 1.00 22.28  ? 153 PHE E CD1 1 
ATOM   9137  C CD2 . PHE D 2 137 ? 168.940 154.405 201.049 1.00 23.36  ? 153 PHE E CD2 1 
ATOM   9138  C CE1 . PHE D 2 137 ? 169.629 151.793 200.573 1.00 21.48  ? 153 PHE E CE1 1 
ATOM   9139  C CE2 . PHE D 2 137 ? 170.258 154.016 201.120 1.00 23.06  ? 153 PHE E CE2 1 
ATOM   9140  C CZ  . PHE D 2 137 ? 170.601 152.711 200.882 1.00 21.60  ? 153 PHE E CZ  1 
ATOM   9141  N N   . LEU D 2 138 ? 164.563 152.246 202.502 1.00 19.57  ? 154 LEU E N   1 
ATOM   9142  C CA  . LEU D 2 138 ? 164.361 151.399 203.671 1.00 20.93  ? 154 LEU E CA  1 
ATOM   9143  C C   . LEU D 2 138 ? 163.633 150.113 203.307 1.00 19.45  ? 154 LEU E C   1 
ATOM   9144  O O   . LEU D 2 138 ? 163.955 149.042 203.832 1.00 21.36  ? 154 LEU E O   1 
ATOM   9145  C CB  . LEU D 2 138 ? 163.588 152.184 204.731 1.00 21.55  ? 154 LEU E CB  1 
ATOM   9146  C CG  . LEU D 2 138 ? 163.886 152.005 206.218 1.00 23.45  ? 154 LEU E CG  1 
ATOM   9147  C CD1 . LEU D 2 138 ? 165.372 152.022 206.498 1.00 23.43  ? 154 LEU E CD1 1 
ATOM   9148  C CD2 . LEU D 2 138 ? 163.202 153.106 206.991 1.00 25.79  ? 154 LEU E CD2 1 
ATOM   9149  N N   . ALA D 2 139 ? 162.641 150.200 202.418 1.00 19.54  ? 155 ALA E N   1 
ATOM   9150  C CA  . ALA D 2 139 ? 161.933 149.003 201.975 1.00 18.79  ? 155 ALA E CA  1 
ATOM   9151  C C   . ALA D 2 139 ? 162.792 148.145 201.056 1.00 23.90  ? 155 ALA E C   1 
ATOM   9152  O O   . ALA D 2 139 ? 162.597 146.927 200.987 1.00 30.40  ? 155 ALA E O   1 
ATOM   9153  C CB  . ALA D 2 139 ? 160.634 149.394 201.272 1.00 16.94  ? 155 ALA E CB  1 
ATOM   9154  N N   . ARG D 2 140 ? 163.735 148.759 200.337 1.00 22.66  ? 156 ARG E N   1 
ATOM   9155  C CA  . ARG D 2 140 ? 164.623 147.997 199.466 1.00 20.66  ? 156 ARG E CA  1 
ATOM   9156  C C   . ARG D 2 140 ? 165.502 147.040 200.262 1.00 24.13  ? 156 ARG E C   1 
ATOM   9157  O O   . ARG D 2 140 ? 165.713 145.893 199.853 1.00 31.01  ? 156 ARG E O   1 
ATOM   9158  C CB  . ARG D 2 140 ? 165.488 148.954 198.647 1.00 19.98  ? 156 ARG E CB  1 
ATOM   9159  C CG  . ARG D 2 140 ? 165.805 148.483 197.249 1.00 21.25  ? 156 ARG E CG  1 
ATOM   9160  C CD  . ARG D 2 140 ? 167.011 149.206 196.680 1.00 17.57  ? 156 ARG E CD  1 
ATOM   9161  N NE  . ARG D 2 140 ? 166.999 150.640 196.947 1.00 16.44  ? 156 ARG E NE  1 
ATOM   9162  C CZ  . ARG D 2 140 ? 166.246 151.519 196.300 1.00 20.19  ? 156 ARG E CZ  1 
ATOM   9163  N NH1 . ARG D 2 140 ? 165.399 151.142 195.357 1.00 22.84  ? 156 ARG E NH1 1 
ATOM   9164  N NH2 . ARG D 2 140 ? 166.347 152.808 196.604 1.00 16.70  ? 156 ARG E NH2 1 
ATOM   9165  N N   . THR D 2 141 ? 166.021 147.490 201.404 1.00 23.19  ? 157 THR E N   1 
ATOM   9166  C CA  . THR D 2 141 ? 167.046 146.765 202.142 1.00 26.92  ? 157 THR E CA  1 
ATOM   9167  C C   . THR D 2 141 ? 166.519 146.119 203.420 1.00 32.74  ? 157 THR E C   1 
ATOM   9168  O O   . THR D 2 141 ? 167.283 145.941 204.374 1.00 40.18  ? 157 THR E O   1 
ATOM   9169  C CB  . THR D 2 141 ? 168.210 147.698 202.472 1.00 26.59  ? 157 THR E CB  1 
ATOM   9170  O OG1 . THR D 2 141 ? 167.756 148.744 203.338 1.00 22.98  ? 157 THR E OG1 1 
ATOM   9171  C CG2 . THR D 2 141 ? 168.761 148.318 201.205 1.00 25.90  ? 157 THR E CG2 1 
ATOM   9172  N N   . VAL D 2 142 ? 165.239 145.763 203.463 1.00 32.76  ? 158 VAL E N   1 
ATOM   9173  C CA  . VAL D 2 142 ? 164.669 145.123 204.643 1.00 37.50  ? 158 VAL E CA  1 
ATOM   9174  C C   . VAL D 2 142 ? 165.032 143.643 204.640 1.00 43.64  ? 158 VAL E C   1 
ATOM   9175  O O   . VAL D 2 142 ? 165.101 143.003 203.584 1.00 46.61  ? 158 VAL E O   1 
ATOM   9176  C CB  . VAL D 2 142 ? 163.145 145.344 204.695 1.00 32.21  ? 158 VAL E CB  1 
ATOM   9177  C CG1 . VAL D 2 142 ? 162.449 144.619 203.558 1.00 35.38  ? 158 VAL E CG1 1 
ATOM   9178  C CG2 . VAL D 2 142 ? 162.588 144.908 206.036 1.00 38.36  ? 158 VAL E CG2 1 
ATOM   9179  N N   . GLN D 2 143 ? 165.293 143.099 205.826 1.00 47.53  ? 159 GLN E N   1 
ATOM   9180  C CA  . GLN D 2 143 ? 165.712 141.710 205.969 1.00 48.95  ? 159 GLN E CA  1 
ATOM   9181  C C   . GLN D 2 143 ? 165.192 141.180 207.302 1.00 55.92  ? 159 GLN E C   1 
ATOM   9182  O O   . GLN D 2 143 ? 164.402 141.839 207.984 1.00 60.04  ? 159 GLN E O   1 
ATOM   9183  C CB  . GLN D 2 143 ? 167.236 141.592 205.850 1.00 51.57  ? 159 GLN E CB  1 
ATOM   9184  C CG  . GLN D 2 143 ? 167.995 142.090 207.068 1.00 54.29  ? 159 GLN E CG  1 
ATOM   9185  C CD  . GLN D 2 143 ? 169.468 142.299 206.793 1.00 58.45  ? 159 GLN E CD  1 
ATOM   9186  O OE1 . GLN D 2 143 ? 169.963 141.967 205.717 1.00 63.78  ? 159 GLN E OE1 1 
ATOM   9187  N NE2 . GLN D 2 143 ? 170.179 142.848 207.769 1.00 59.07  ? 159 GLN E NE2 1 
ATOM   9188  N N   . VAL D 2 144 ? 165.641 139.979 207.673 1.00 56.19  ? 160 VAL E N   1 
ATOM   9189  C CA  . VAL D 2 144 ? 165.172 139.345 208.904 1.00 58.12  ? 160 VAL E CA  1 
ATOM   9190  C C   . VAL D 2 144 ? 165.599 140.149 210.125 1.00 57.62  ? 160 VAL E C   1 
ATOM   9191  O O   . VAL D 2 144 ? 164.816 140.344 211.064 1.00 56.42  ? 160 VAL E O   1 
ATOM   9192  C CB  . VAL D 2 144 ? 165.676 137.891 208.978 1.00 64.22  ? 160 VAL E CB  1 
ATOM   9193  C CG1 . VAL D 2 144 ? 165.659 137.385 210.411 1.00 67.36  ? 160 VAL E CG1 1 
ATOM   9194  C CG2 . VAL D 2 144 ? 164.828 137.000 208.100 1.00 66.08  ? 160 VAL E CG2 1 
ATOM   9195  N N   . GLY D 2 145 ? 166.841 140.633 210.134 1.00 58.91  ? 161 GLY E N   1 
ATOM   9196  C CA  . GLY D 2 145 ? 167.371 141.304 211.307 1.00 59.93  ? 161 GLY E CA  1 
ATOM   9197  C C   . GLY D 2 145 ? 166.677 142.605 211.655 1.00 60.09  ? 161 GLY E C   1 
ATOM   9198  O O   . GLY D 2 145 ? 166.873 143.124 212.758 1.00 63.47  ? 161 GLY E O   1 
ATOM   9199  N N   . ASN D 2 146 ? 165.873 143.153 210.738 1.00 57.08  ? 162 ASN E N   1 
ATOM   9200  C CA  . ASN D 2 146 ? 165.187 144.407 211.024 1.00 56.32  ? 162 ASN E CA  1 
ATOM   9201  C C   . ASN D 2 146 ? 163.753 144.444 210.500 1.00 56.64  ? 162 ASN E C   1 
ATOM   9202  O O   . ASN D 2 146 ? 163.164 145.527 210.434 1.00 59.95  ? 162 ASN E O   1 
ATOM   9203  C CB  . ASN D 2 146 ? 165.972 145.591 210.448 1.00 55.86  ? 162 ASN E CB  1 
ATOM   9204  C CG  . ASN D 2 146 ? 166.227 145.454 208.962 1.00 54.50  ? 162 ASN E CG  1 
ATOM   9205  O OD1 . ASN D 2 146 ? 165.958 144.413 208.368 1.00 55.87  ? 162 ASN E OD1 1 
ATOM   9206  N ND2 . ASN D 2 146 ? 166.752 146.510 208.354 1.00 51.59  ? 162 ASN E ND2 1 
ATOM   9207  N N   . CYS D 2 147 ? 163.170 143.301 210.129 1.00 54.03  ? 163 CYS E N   1 
ATOM   9208  C CA  . CYS D 2 147 ? 161.819 143.316 209.571 1.00 53.30  ? 163 CYS E CA  1 
ATOM   9209  C C   . CYS D 2 147 ? 160.803 143.798 210.599 1.00 56.14  ? 163 CYS E C   1 
ATOM   9210  O O   . CYS D 2 147 ? 159.956 144.647 210.301 1.00 56.71  ? 163 CYS E O   1 
ATOM   9211  C CB  . CYS D 2 147 ? 161.441 141.928 209.055 1.00 57.48  ? 163 CYS E CB  1 
ATOM   9212  S SG  . CYS D 2 147 ? 161.763 140.579 210.207 1.00 75.31  ? 163 CYS E SG  1 
ATOM   9213  N N   . LEU D 2 148 ? 160.880 143.274 211.824 1.00 59.92  ? 164 LEU E N   1 
ATOM   9214  C CA  . LEU D 2 148 ? 159.951 143.702 212.865 1.00 60.12  ? 164 LEU E CA  1 
ATOM   9215  C C   . LEU D 2 148 ? 160.245 145.127 213.315 1.00 59.67  ? 164 LEU E C   1 
ATOM   9216  O O   . LEU D 2 148 ? 159.320 145.910 213.564 1.00 61.44  ? 164 LEU E O   1 
ATOM   9217  C CB  . LEU D 2 148 ? 160.012 142.738 214.049 1.00 64.75  ? 164 LEU E CB  1 
ATOM   9218  C CG  . LEU D 2 148 ? 159.480 141.325 213.800 1.00 67.01  ? 164 LEU E CG  1 
ATOM   9219  C CD1 . LEU D 2 148 ? 159.554 140.494 215.069 1.00 77.79  ? 164 LEU E CD1 1 
ATOM   9220  C CD2 . LEU D 2 148 ? 158.058 141.366 213.265 1.00 64.96  ? 164 LEU E CD2 1 
ATOM   9221  N N   . GLN D 2 149 ? 161.527 145.483 213.421 1.00 59.07  ? 165 GLN E N   1 
ATOM   9222  C CA  . GLN D 2 149 ? 161.893 146.842 213.808 1.00 58.04  ? 165 GLN E CA  1 
ATOM   9223  C C   . GLN D 2 149 ? 161.444 147.854 212.761 1.00 55.91  ? 165 GLN E C   1 
ATOM   9224  O O   . GLN D 2 149 ? 160.948 148.932 213.104 1.00 57.14  ? 165 GLN E O   1 
ATOM   9225  C CB  . GLN D 2 149 ? 163.402 146.929 214.037 1.00 60.31  ? 165 GLN E CB  1 
ATOM   9226  C CG  . GLN D 2 149 ? 163.970 148.335 213.972 1.00 59.29  ? 165 GLN E CG  1 
ATOM   9227  C CD  . GLN D 2 149 ? 165.401 148.358 213.474 1.00 64.23  ? 165 GLN E CD  1 
ATOM   9228  O OE1 . GLN D 2 149 ? 165.683 148.854 212.384 1.00 62.03  ? 165 GLN E OE1 1 
ATOM   9229  N NE2 . GLN D 2 149 ? 166.313 147.818 214.273 1.00 68.75  ? 165 GLN E NE2 1 
ATOM   9230  N N   . VAL D 2 150 ? 161.604 147.524 211.478 1.00 52.67  ? 166 VAL E N   1 
ATOM   9231  C CA  . VAL D 2 150 ? 161.150 148.420 210.418 1.00 48.56  ? 166 VAL E CA  1 
ATOM   9232  C C   . VAL D 2 150 ? 159.626 148.483 210.383 1.00 51.16  ? 166 VAL E C   1 
ATOM   9233  O O   . VAL D 2 150 ? 159.042 149.547 210.144 1.00 55.58  ? 166 VAL E O   1 
ATOM   9234  C CB  . VAL D 2 150 ? 161.741 147.984 209.065 1.00 45.36  ? 166 VAL E CB  1 
ATOM   9235  C CG1 . VAL D 2 150 ? 160.952 148.569 207.918 1.00 44.55  ? 166 VAL E CG1 1 
ATOM   9236  C CG2 . VAL D 2 150 ? 163.195 148.404 208.968 1.00 45.17  ? 166 VAL E CG2 1 
ATOM   9237  N N   . MET D 2 151 ? 158.957 147.352 210.624 1.00 52.04  ? 167 MET E N   1 
ATOM   9238  C CA  . MET D 2 151 ? 157.497 147.350 210.655 1.00 56.59  ? 167 MET E CA  1 
ATOM   9239  C C   . MET D 2 151 ? 156.965 148.235 211.773 1.00 59.05  ? 167 MET E C   1 
ATOM   9240  O O   . MET D 2 151 ? 155.992 148.973 211.581 1.00 63.95  ? 167 MET E O   1 
ATOM   9241  C CB  . MET D 2 151 ? 156.975 145.924 210.819 1.00 59.42  ? 167 MET E CB  1 
ATOM   9242  C CG  . MET D 2 151 ? 155.706 145.635 210.041 1.00 59.68  ? 167 MET E CG  1 
ATOM   9243  S SD  . MET D 2 151 ? 155.245 143.903 210.162 1.00 66.08  ? 167 MET E SD  1 
ATOM   9244  C CE  . MET D 2 151 ? 155.385 143.670 211.928 1.00 65.37  ? 167 MET E CE  1 
ATOM   9245  N N   . TRP D 2 152 ? 157.579 148.163 212.954 1.00 57.66  ? 168 TRP E N   1 
ATOM   9246  C CA  . TRP D 2 152 ? 157.176 149.039 214.048 1.00 61.70  ? 168 TRP E CA  1 
ATOM   9247  C C   . TRP D 2 152 ? 157.552 150.486 213.755 1.00 60.26  ? 168 TRP E C   1 
ATOM   9248  O O   . TRP D 2 152 ? 156.842 151.413 214.160 1.00 65.63  ? 168 TRP E O   1 
ATOM   9249  C CB  . TRP D 2 152 ? 157.807 148.558 215.355 1.00 68.68  ? 168 TRP E CB  1 
ATOM   9250  C CG  . TRP D 2 152 ? 156.959 148.798 216.566 1.00 77.72  ? 168 TRP E CG  1 
ATOM   9251  C CD1 . TRP D 2 152 ? 155.891 148.056 216.975 1.00 81.77  ? 168 TRP E CD1 1 
ATOM   9252  C CD2 . TRP D 2 152 ? 157.133 149.826 217.548 1.00 80.10  ? 168 TRP E CD2 1 
ATOM   9253  N NE1 . TRP D 2 152 ? 155.372 148.572 218.137 1.00 84.16  ? 168 TRP E NE1 1 
ATOM   9254  C CE2 . TRP D 2 152 ? 156.119 149.658 218.512 1.00 82.23  ? 168 TRP E CE2 1 
ATOM   9255  C CE3 . TRP D 2 152 ? 158.041 150.878 217.702 1.00 78.95  ? 168 TRP E CE3 1 
ATOM   9256  C CZ2 . TRP D 2 152 ? 155.988 150.500 219.613 1.00 84.33  ? 168 TRP E CZ2 1 
ATOM   9257  C CZ3 . TRP D 2 152 ? 157.909 151.714 218.795 1.00 81.99  ? 168 TRP E CZ3 1 
ATOM   9258  C CH2 . TRP D 2 152 ? 156.891 151.521 219.736 1.00 84.82  ? 168 TRP E CH2 1 
ATOM   9259  N N   . LEU D 2 153 ? 158.665 150.695 213.049 1.00 59.42  ? 169 LEU E N   1 
ATOM   9260  C CA  . LEU D 2 153 ? 159.068 152.041 212.653 1.00 55.33  ? 169 LEU E CA  1 
ATOM   9261  C C   . LEU D 2 153 ? 158.069 152.661 211.684 1.00 53.16  ? 169 LEU E C   1 
ATOM   9262  O O   . LEU D 2 153 ? 157.737 153.846 211.797 1.00 54.21  ? 169 LEU E O   1 
ATOM   9263  C CB  . LEU D 2 153 ? 160.462 151.997 212.031 1.00 53.30  ? 169 LEU E CB  1 
ATOM   9264  C CG  . LEU D 2 153 ? 161.093 153.318 211.603 1.00 50.95  ? 169 LEU E CG  1 
ATOM   9265  C CD1 . LEU D 2 153 ? 161.814 153.959 212.770 1.00 52.70  ? 169 LEU E CD1 1 
ATOM   9266  C CD2 . LEU D 2 153 ? 162.042 153.081 210.446 1.00 42.38  ? 169 LEU E CD2 1 
ATOM   9267  N N   . ALA D 2 154 ? 157.588 151.880 210.715 1.00 53.40  ? 170 ALA E N   1 
ATOM   9268  C CA  . ALA D 2 154 ? 156.604 152.388 209.769 1.00 52.84  ? 170 ALA E CA  1 
ATOM   9269  C C   . ALA D 2 154 ? 155.220 152.517 210.388 1.00 59.70  ? 170 ALA E C   1 
ATOM   9270  O O   . ALA D 2 154 ? 154.345 153.152 209.792 1.00 61.38  ? 170 ALA E O   1 
ATOM   9271  C CB  . ALA D 2 154 ? 156.538 151.484 208.539 1.00 47.22  ? 170 ALA E CB  1 
ATOM   9272  N N   . ASP D 2 155 ? 155.000 151.922 211.562 1.00 61.10  ? 171 ASP E N   1 
ATOM   9273  C CA  . ASP D 2 155 ? 153.718 152.075 212.239 1.00 63.44  ? 171 ASP E CA  1 
ATOM   9274  C C   . ASP D 2 155 ? 153.584 153.458 212.863 1.00 63.56  ? 171 ASP E C   1 
ATOM   9275  O O   . ASP D 2 155 ? 152.512 154.071 212.804 1.00 66.31  ? 171 ASP E O   1 
ATOM   9276  C CB  . ASP D 2 155 ? 153.556 150.989 213.302 1.00 67.23  ? 171 ASP E CB  1 
ATOM   9277  C CG  . ASP D 2 155 ? 152.105 150.647 213.567 1.00 77.27  ? 171 ASP E CG  1 
ATOM   9278  O OD1 . ASP D 2 155 ? 151.302 150.668 212.611 1.00 74.26  ? 171 ASP E OD1 1 
ATOM   9279  O OD2 . ASP D 2 155 ? 151.768 150.361 214.735 1.00 82.26  ? 171 ASP E OD2 1 
ATOM   9280  N N   . ARG D 2 156 ? 154.661 153.965 213.466 1.00 61.11  ? 172 ARG E N   1 
ATOM   9281  C CA  . ARG D 2 156 ? 154.621 155.282 214.088 1.00 60.61  ? 172 ARG E CA  1 
ATOM   9282  C C   . ARG D 2 156 ? 154.541 156.406 213.066 1.00 63.81  ? 172 ARG E C   1 
ATOM   9283  O O   . ARG D 2 156 ? 153.988 157.467 213.374 1.00 65.86  ? 172 ARG E O   1 
ATOM   9284  C CB  . ARG D 2 156 ? 155.849 155.481 214.975 1.00 59.93  ? 172 ARG E CB  1 
ATOM   9285  C CG  . ARG D 2 156 ? 156.026 154.411 216.032 1.00 65.21  ? 172 ARG E CG  1 
ATOM   9286  C CD  . ARG D 2 156 ? 157.463 153.931 216.097 1.00 66.53  ? 172 ARG E CD  1 
ATOM   9287  N NE  . ARG D 2 156 ? 158.415 154.987 215.776 1.00 69.36  ? 172 ARG E NE  1 
ATOM   9288  C CZ  . ARG D 2 156 ? 159.712 154.930 216.047 1.00 70.75  ? 172 ARG E CZ  1 
ATOM   9289  N NH1 . ARG D 2 156 ? 160.247 153.883 216.651 1.00 67.74  ? 172 ARG E NH1 1 
ATOM   9290  N NH2 . ARG D 2 156 ? 160.492 155.951 215.702 1.00 69.42  ? 172 ARG E NH2 1 
ATOM   9291  N N   . HIS D 2 157 ? 155.078 156.203 211.865 1.00 61.59  ? 173 HIS E N   1 
ATOM   9292  C CA  . HIS D 2 157 ? 155.125 157.241 210.848 1.00 56.20  ? 173 HIS E CA  1 
ATOM   9293  C C   . HIS D 2 157 ? 154.042 157.090 209.789 1.00 58.75  ? 173 HIS E C   1 
ATOM   9294  O O   . HIS D 2 157 ? 153.993 157.900 208.858 1.00 60.78  ? 173 HIS E O   1 
ATOM   9295  C CB  . HIS D 2 157 ? 156.507 157.260 210.188 1.00 51.58  ? 173 HIS E CB  1 
ATOM   9296  C CG  . HIS D 2 157 ? 157.615 157.617 211.130 1.00 52.93  ? 173 HIS E CG  1 
ATOM   9297  N ND1 . HIS D 2 157 ? 157.583 158.743 211.923 1.00 53.31  ? 173 HIS E ND1 1 
ATOM   9298  C CD2 . HIS D 2 157 ? 158.778 156.988 211.418 1.00 54.34  ? 173 HIS E CD2 1 
ATOM   9299  C CE1 . HIS D 2 157 ? 158.682 158.797 212.653 1.00 53.47  ? 173 HIS E CE1 1 
ATOM   9300  N NE2 . HIS D 2 157 ? 159.425 157.744 212.366 1.00 55.32  ? 173 HIS E NE2 1 
ATOM   9301  N N   . SER D 2 158 ? 153.176 156.082 209.910 1.00 62.44  ? 174 SER E N   1 
ATOM   9302  C CA  . SER D 2 158 ? 152.024 155.893 209.027 1.00 64.62  ? 174 SER E CA  1 
ATOM   9303  C C   . SER D 2 158 ? 152.452 155.800 207.561 1.00 64.79  ? 174 SER E C   1 
ATOM   9304  O O   . SER D 2 158 ? 152.043 156.591 206.709 1.00 64.89  ? 174 SER E O   1 
ATOM   9305  C CB  . SER D 2 158 ? 150.994 157.008 209.233 1.00 65.04  ? 174 SER E CB  1 
ATOM   9306  O OG  . SER D 2 158 ? 150.692 157.170 210.608 1.00 68.51  ? 174 SER E OG  1 
ATOM   9307  N N   . ASP D 2 159 ? 153.291 154.806 207.280 1.00 59.96  ? 175 ASP E N   1 
ATOM   9308  C CA  . ASP D 2 159 ? 153.782 154.563 205.929 1.00 53.93  ? 175 ASP E CA  1 
ATOM   9309  C C   . ASP D 2 159 ? 153.217 153.247 205.417 1.00 55.14  ? 175 ASP E C   1 
ATOM   9310  O O   . ASP D 2 159 ? 153.661 152.177 205.862 1.00 55.21  ? 175 ASP E O   1 
ATOM   9311  C CB  . ASP D 2 159 ? 155.310 154.531 205.910 1.00 50.54  ? 175 ASP E CB  1 
ATOM   9312  C CG  . ASP D 2 159 ? 155.882 154.853 204.546 1.00 51.24  ? 175 ASP E CG  1 
ATOM   9313  O OD1 . ASP D 2 159 ? 155.228 154.532 203.533 1.00 53.60  ? 175 ASP E OD1 1 
ATOM   9314  O OD2 . ASP D 2 159 ? 156.991 155.421 204.487 1.00 48.28  ? 175 ASP E OD2 1 
ATOM   9315  N N   . PRO D 2 160 ? 152.249 153.263 204.501 1.00 57.59  ? 176 PRO E N   1 
ATOM   9316  C CA  . PRO D 2 160 ? 151.654 152.005 204.026 1.00 55.63  ? 176 PRO E CA  1 
ATOM   9317  C C   . PRO D 2 160 ? 152.622 151.114 203.260 1.00 55.75  ? 176 PRO E C   1 
ATOM   9318  O O   . PRO D 2 160 ? 152.670 149.904 203.499 1.00 56.55  ? 176 PRO E O   1 
ATOM   9319  C CB  . PRO D 2 160 ? 150.510 152.480 203.120 1.00 55.26  ? 176 PRO E CB  1 
ATOM   9320  C CG  . PRO D 2 160 ? 150.234 153.885 203.545 1.00 55.89  ? 176 PRO E CG  1 
ATOM   9321  C CD  . PRO D 2 160 ? 151.556 154.442 203.959 1.00 57.95  ? 176 PRO E CD  1 
ATOM   9322  N N   . GLU D 2 161 ? 153.393 151.695 202.338 1.00 53.58  ? 177 GLU E N   1 
ATOM   9323  C CA  . GLU D 2 161 ? 154.244 150.893 201.461 1.00 52.65  ? 177 GLU E CA  1 
ATOM   9324  C C   . GLU D 2 161 ? 155.353 150.197 202.244 1.00 50.93  ? 177 GLU E C   1 
ATOM   9325  O O   . GLU D 2 161 ? 155.592 148.994 202.074 1.00 51.85  ? 177 GLU E O   1 
ATOM   9326  C CB  . GLU D 2 161 ? 154.833 151.779 200.363 1.00 56.30  ? 177 GLU E CB  1 
ATOM   9327  C CG  . GLU D 2 161 ? 153.885 152.058 199.207 1.00 61.20  ? 177 GLU E CG  1 
ATOM   9328  C CD  . GLU D 2 161 ? 153.892 150.958 198.164 1.00 68.16  ? 177 GLU E CD  1 
ATOM   9329  O OE1 . GLU D 2 161 ? 153.381 149.855 198.454 1.00 65.21  ? 177 GLU E OE1 1 
ATOM   9330  O OE2 . GLU D 2 161 ? 154.407 151.196 197.051 1.00 70.23  ? 177 GLU E OE2 1 
ATOM   9331  N N   . LEU D 2 162 ? 156.046 150.943 203.106 1.00 45.05  ? 178 LEU E N   1 
ATOM   9332  C CA  . LEU D 2 162 ? 157.099 150.346 203.919 1.00 41.91  ? 178 LEU E CA  1 
ATOM   9333  C C   . LEU D 2 162 ? 156.522 149.319 204.884 1.00 49.65  ? 178 LEU E C   1 
ATOM   9334  O O   . LEU D 2 162 ? 157.147 148.284 205.153 1.00 54.84  ? 178 LEU E O   1 
ATOM   9335  C CB  . LEU D 2 162 ? 157.855 151.436 204.676 1.00 38.46  ? 178 LEU E CB  1 
ATOM   9336  C CG  . LEU D 2 162 ? 158.971 150.971 205.608 1.00 37.80  ? 178 LEU E CG  1 
ATOM   9337  C CD1 . LEU D 2 162 ? 159.931 150.076 204.856 1.00 35.23  ? 178 LEU E CD1 1 
ATOM   9338  C CD2 . LEU D 2 162 ? 159.697 152.154 206.211 1.00 34.28  ? 178 LEU E CD2 1 
ATOM   9339  N N   . TYR D 2 163 ? 155.329 149.591 205.417 1.00 50.10  ? 179 TYR E N   1 
ATOM   9340  C CA  . TYR D 2 163 ? 154.670 148.637 206.301 1.00 50.99  ? 179 TYR E CA  1 
ATOM   9341  C C   . TYR D 2 163 ? 154.390 147.326 205.580 1.00 51.96  ? 179 TYR E C   1 
ATOM   9342  O O   . TYR D 2 163 ? 154.654 146.247 206.116 1.00 54.89  ? 179 TYR E O   1 
ATOM   9343  C CB  . TYR D 2 163 ? 153.376 149.240 206.847 1.00 55.26  ? 179 TYR E CB  1 
ATOM   9344  C CG  . TYR D 2 163 ? 152.689 148.387 207.886 1.00 59.16  ? 179 TYR E CG  1 
ATOM   9345  C CD1 . TYR D 2 163 ? 153.120 148.381 209.204 1.00 57.84  ? 179 TYR E CD1 1 
ATOM   9346  C CD2 . TYR D 2 163 ? 151.607 147.590 207.547 1.00 59.60  ? 179 TYR E CD2 1 
ATOM   9347  C CE1 . TYR D 2 163 ? 152.493 147.603 210.154 1.00 61.23  ? 179 TYR E CE1 1 
ATOM   9348  C CE2 . TYR D 2 163 ? 150.975 146.809 208.488 1.00 65.31  ? 179 TYR E CE2 1 
ATOM   9349  C CZ  . TYR D 2 163 ? 151.421 146.818 209.789 1.00 68.95  ? 179 TYR E CZ  1 
ATOM   9350  O OH  . TYR D 2 163 ? 150.789 146.039 210.726 1.00 75.74  ? 179 TYR E OH  1 
ATOM   9351  N N   . THR D 2 164 ? 153.864 147.400 204.354 1.00 49.70  ? 180 THR E N   1 
ATOM   9352  C CA  . THR D 2 164 ? 153.595 146.180 203.599 1.00 50.86  ? 180 THR E CA  1 
ATOM   9353  C C   . THR D 2 164 ? 154.882 145.444 203.250 1.00 52.36  ? 180 THR E C   1 
ATOM   9354  O O   . THR D 2 164 ? 154.923 144.210 203.286 1.00 56.40  ? 180 THR E O   1 
ATOM   9355  C CB  . THR D 2 164 ? 152.802 146.491 202.329 1.00 51.41  ? 180 THR E CB  1 
ATOM   9356  O OG1 . THR D 2 164 ? 153.553 147.379 201.493 1.00 57.21  ? 180 THR E OG1 1 
ATOM   9357  C CG2 . THR D 2 164 ? 151.461 147.118 202.670 1.00 50.08  ? 180 THR E CG2 1 
ATOM   9358  N N   . ALA D 2 165 ? 155.943 146.179 202.904 1.00 51.44  ? 181 ALA E N   1 
ATOM   9359  C CA  . ALA D 2 165 ? 157.211 145.530 202.579 1.00 47.45  ? 181 ALA E CA  1 
ATOM   9360  C C   . ALA D 2 165 ? 157.769 144.772 203.780 1.00 48.41  ? 181 ALA E C   1 
ATOM   9361  O O   . ALA D 2 165 ? 158.144 143.597 203.672 1.00 52.45  ? 181 ALA E O   1 
ATOM   9362  C CB  . ALA D 2 165 ? 158.216 146.566 202.079 1.00 42.49  ? 181 ALA E CB  1 
ATOM   9363  N N   . ALA D 2 166 ? 157.819 145.429 204.942 1.00 48.93  ? 182 ALA E N   1 
ATOM   9364  C CA  . ALA D 2 166 ? 158.319 144.766 206.143 1.00 47.45  ? 182 ALA E CA  1 
ATOM   9365  C C   . ALA D 2 166 ? 157.406 143.622 206.565 1.00 54.25  ? 182 ALA E C   1 
ATOM   9366  O O   . ALA D 2 166 ? 157.879 142.593 207.059 1.00 56.82  ? 182 ALA E O   1 
ATOM   9367  C CB  . ALA D 2 166 ? 158.475 145.777 207.276 1.00 48.15  ? 182 ALA E CB  1 
ATOM   9368  N N   . LYS D 2 167 ? 156.094 143.782 206.376 1.00 57.10  ? 183 LYS E N   1 
ATOM   9369  C CA  . LYS D 2 167 ? 155.150 142.723 206.711 1.00 60.02  ? 183 LYS E CA  1 
ATOM   9370  C C   . LYS D 2 167 ? 155.368 141.492 205.842 1.00 61.21  ? 183 LYS E C   1 
ATOM   9371  O O   . LYS D 2 167 ? 155.349 140.363 206.341 1.00 62.63  ? 183 LYS E O   1 
ATOM   9372  C CB  . LYS D 2 167 ? 153.724 143.250 206.559 1.00 61.44  ? 183 LYS E CB  1 
ATOM   9373  C CG  . LYS D 2 167 ? 152.629 142.268 206.909 1.00 67.55  ? 183 LYS E CG  1 
ATOM   9374  C CD  . LYS D 2 167 ? 151.277 142.961 206.889 1.00 70.47  ? 183 LYS E CD  1 
ATOM   9375  C CE  . LYS D 2 167 ? 151.105 143.784 205.623 1.00 66.56  ? 183 LYS E CE  1 
ATOM   9376  N NZ  . LYS D 2 167 ? 149.724 144.313 205.471 1.00 65.09  ? 183 LYS E NZ  1 
ATOM   9377  N N   . HIS D 2 168 ? 155.574 141.692 204.538 1.00 59.99  ? 184 HIS E N   1 
ATOM   9378  C CA  . HIS D 2 168 ? 155.860 140.571 203.649 1.00 56.84  ? 184 HIS E CA  1 
ATOM   9379  C C   . HIS D 2 168 ? 157.176 139.904 204.023 1.00 57.41  ? 184 HIS E C   1 
ATOM   9380  O O   . HIS D 2 168 ? 157.276 138.671 204.027 1.00 61.59  ? 184 HIS E O   1 
ATOM   9381  C CB  . HIS D 2 168 ? 155.875 141.057 202.196 1.00 58.62  ? 184 HIS E CB  1 
ATOM   9382  C CG  . HIS D 2 168 ? 156.353 140.038 201.205 1.00 69.59  ? 184 HIS E CG  1 
ATOM   9383  N ND1 . HIS D 2 168 ? 157.623 139.504 201.248 1.00 74.94  ? 184 HIS E ND1 1 
ATOM   9384  C CD2 . HIS D 2 168 ? 155.722 139.418 200.178 1.00 72.96  ? 184 HIS E CD2 1 
ATOM   9385  C CE1 . HIS D 2 168 ? 157.763 138.623 200.273 1.00 72.30  ? 184 HIS E CE1 1 
ATOM   9386  N NE2 . HIS D 2 168 ? 156.624 138.553 199.609 1.00 74.36  ? 184 HIS E NE2 1 
ATOM   9387  N N   . CYS D 2 169 ? 158.196 140.703 204.347 1.00 61.09  ? 185 CYS E N   1 
ATOM   9388  C CA  . CYS D 2 169 ? 159.477 140.130 204.749 1.00 58.90  ? 185 CYS E CA  1 
ATOM   9389  C C   . CYS D 2 169 ? 159.337 139.287 206.012 1.00 62.09  ? 185 CYS E C   1 
ATOM   9390  O O   . CYS D 2 169 ? 159.915 138.199 206.107 1.00 66.98  ? 185 CYS E O   1 
ATOM   9391  C CB  . CYS D 2 169 ? 160.508 141.237 204.958 1.00 51.69  ? 185 CYS E CB  1 
ATOM   9392  S SG  . CYS D 2 169 ? 162.074 140.660 205.644 1.00 59.68  ? 185 CYS E SG  1 
ATOM   9393  N N   . ALA D 2 170 ? 158.575 139.775 206.993 1.00 66.58  ? 186 ALA E N   1 
ATOM   9394  C CA  . ALA D 2 170 ? 158.397 139.029 208.235 1.00 68.24  ? 186 ALA E CA  1 
ATOM   9395  C C   . ALA D 2 170 ? 157.523 137.796 208.040 1.00 67.80  ? 186 ALA E C   1 
ATOM   9396  O O   . ALA D 2 170 ? 157.738 136.776 208.703 1.00 69.56  ? 186 ALA E O   1 
ATOM   9397  C CB  . ALA D 2 170 ? 157.802 139.934 209.312 1.00 69.13  ? 186 ALA E CB  1 
ATOM   9398  N N   . LYS D 2 171 ? 156.534 137.871 207.148 1.00 67.75  ? 187 LYS E N   1 
ATOM   9399  C CA  . LYS D 2 171 ? 155.651 136.733 206.916 1.00 69.24  ? 187 LYS E CA  1 
ATOM   9400  C C   . LYS D 2 171 ? 156.366 135.621 206.158 1.00 73.56  ? 187 LYS E C   1 
ATOM   9401  O O   . LYS D 2 171 ? 156.160 134.436 206.445 1.00 78.30  ? 187 LYS E O   1 
ATOM   9402  C CB  . LYS D 2 171 ? 154.404 137.197 206.162 1.00 68.85  ? 187 LYS E CB  1 
ATOM   9403  C CG  . LYS D 2 171 ? 153.708 136.121 205.361 1.00 73.81  ? 187 LYS E CG  1 
ATOM   9404  C CD  . LYS D 2 171 ? 153.910 136.327 203.870 1.00 72.98  ? 187 LYS E CD  1 
ATOM   9405  C CE  . LYS D 2 171 ? 152.928 137.341 203.314 1.00 71.26  ? 187 LYS E CE  1 
ATOM   9406  N NZ  . LYS D 2 171 ? 152.962 137.371 201.827 1.00 71.57  ? 187 LYS E NZ  1 
ATOM   9407  N N   . THR D 2 172 ? 157.213 135.981 205.191 1.00 76.45  ? 188 THR E N   1 
ATOM   9408  C CA  . THR D 2 172 ? 157.936 134.968 204.428 1.00 74.72  ? 188 THR E CA  1 
ATOM   9409  C C   . THR D 2 172 ? 158.909 134.185 205.303 1.00 78.88  ? 188 THR E C   1 
ATOM   9410  O O   . THR D 2 172 ? 159.126 132.991 205.068 1.00 87.29  ? 188 THR E O   1 
ATOM   9411  C CB  . THR D 2 172 ? 158.678 135.620 203.261 1.00 72.54  ? 188 THR E CB  1 
ATOM   9412  O OG1 . THR D 2 172 ? 157.775 136.452 202.526 1.00 70.44  ? 188 THR E OG1 1 
ATOM   9413  C CG2 . THR D 2 172 ? 159.243 134.565 202.328 1.00 78.75  ? 188 THR E CG2 1 
ATOM   9414  N N   . HIS D 2 173 ? 159.494 134.824 206.313 1.00 75.19  ? 189 HIS E N   1 
ATOM   9415  C CA  . HIS D 2 173 ? 160.475 134.193 207.190 1.00 80.42  ? 189 HIS E CA  1 
ATOM   9416  C C   . HIS D 2 173 ? 159.944 134.070 208.616 1.00 81.81  ? 189 HIS E C   1 
ATOM   9417  O O   . HIS D 2 173 ? 160.652 134.346 209.586 1.00 82.92  ? 189 HIS E O   1 
ATOM   9418  C CB  . HIS D 2 173 ? 161.797 134.958 207.185 1.00 83.70  ? 189 HIS E CB  1 
ATOM   9419  C CG  . HIS D 2 173 ? 162.432 135.082 205.832 1.00 85.72  ? 189 HIS E CG  1 
ATOM   9420  N ND1 . HIS D 2 173 ? 161.697 135.078 204.667 1.00 86.08  ? 189 HIS E ND1 1 
ATOM   9421  C CD2 . HIS D 2 173 ? 163.728 135.192 205.456 1.00 85.01  ? 189 HIS E CD2 1 
ATOM   9422  C CE1 . HIS D 2 173 ? 162.510 135.193 203.633 1.00 87.06  ? 189 HIS E CE1 1 
ATOM   9423  N NE2 . HIS D 2 173 ? 163.749 135.263 204.085 1.00 90.20  ? 189 HIS E NE2 1 
ATOM   9424  N N   . LEU D 2 174 ? 158.681 133.656 208.751 1.00 82.79  ? 190 LEU E N   1 
ATOM   9425  C CA  . LEU D 2 174 ? 158.058 133.563 210.068 1.00 83.99  ? 190 LEU E CA  1 
ATOM   9426  C C   . LEU D 2 174 ? 158.726 132.506 210.939 1.00 89.26  ? 190 LEU E C   1 
ATOM   9427  O O   . LEU D 2 174 ? 158.768 132.655 212.166 1.00 89.02  ? 190 LEU E O   1 
ATOM   9428  C CB  . LEU D 2 174 ? 156.566 133.261 209.914 1.00 83.16  ? 190 LEU E CB  1 
ATOM   9429  C CG  . LEU D 2 174 ? 155.552 133.938 210.842 1.00 83.59  ? 190 LEU E CG  1 
ATOM   9430  C CD1 . LEU D 2 174 ? 154.144 133.560 210.426 1.00 86.52  ? 190 LEU E CD1 1 
ATOM   9431  C CD2 . LEU D 2 174 ? 155.779 133.586 212.300 1.00 84.47  ? 190 LEU E CD2 1 
ATOM   9432  N N   . ALA D 2 175 ? 159.252 131.440 210.331 1.00 91.46  ? 191 ALA E N   1 
ATOM   9433  C CA  . ALA D 2 175 ? 159.829 130.348 211.109 1.00 88.66  ? 191 ALA E CA  1 
ATOM   9434  C C   . ALA D 2 175 ? 161.012 130.821 211.945 1.00 91.64  ? 191 ALA E C   1 
ATOM   9435  O O   . ALA D 2 175 ? 161.149 130.437 213.112 1.00 92.74  ? 191 ALA E O   1 
ATOM   9436  C CB  . ALA D 2 175 ? 160.251 129.210 210.181 1.00 86.61  ? 191 ALA E CB  1 
ATOM   9437  N N   . GLN D 2 176 ? 161.881 131.652 211.366 1.00 92.00  ? 192 GLN E N   1 
ATOM   9438  C CA  . GLN D 2 176 ? 163.025 132.158 212.116 1.00 89.50  ? 192 GLN E CA  1 
ATOM   9439  C C   . GLN D 2 176 ? 162.604 133.169 213.175 1.00 91.87  ? 192 GLN E C   1 
ATOM   9440  O O   . GLN D 2 176 ? 163.241 133.262 214.229 1.00 91.11  ? 192 GLN E O   1 
ATOM   9441  C CB  . GLN D 2 176 ? 164.044 132.781 211.163 1.00 85.31  ? 192 GLN E CB  1 
ATOM   9442  C CG  . GLN D 2 176 ? 164.800 131.770 210.321 1.00 90.12  ? 192 GLN E CG  1 
ATOM   9443  C CD  . GLN D 2 176 ? 164.945 132.208 208.878 1.00 95.08  ? 192 GLN E CD  1 
ATOM   9444  O OE1 . GLN D 2 176 ? 165.706 133.125 208.570 1.00 94.88  ? 192 GLN E OE1 1 
ATOM   9445  N NE2 . GLN D 2 176 ? 164.213 131.553 207.983 1.00 94.90  ? 192 GLN E NE2 1 
ATOM   9446  N N   . LEU D 2 177 ? 161.543 133.933 212.914 1.00 94.56  ? 193 LEU E N   1 
ATOM   9447  C CA  . LEU D 2 177 ? 161.068 134.936 213.857 1.00 92.25  ? 193 LEU E CA  1 
ATOM   9448  C C   . LEU D 2 177 ? 160.194 134.355 214.959 1.00 94.87  ? 193 LEU E C   1 
ATOM   9449  O O   . LEU D 2 177 ? 159.916 135.057 215.936 1.00 96.75  ? 193 LEU E O   1 
ATOM   9450  C CB  . LEU D 2 177 ? 160.286 136.024 213.118 1.00 85.75  ? 193 LEU E CB  1 
ATOM   9451  C CG  . LEU D 2 177 ? 161.046 136.822 212.061 1.00 80.23  ? 193 LEU E CG  1 
ATOM   9452  C CD1 . LEU D 2 177 ? 160.071 137.477 211.105 1.00 75.89  ? 193 LEU E CD1 1 
ATOM   9453  C CD2 . LEU D 2 177 ? 161.942 137.860 212.714 1.00 78.97  ? 193 LEU E CD2 1 
ATOM   9454  N N   . GLN D 2 178 ? 159.756 133.101 214.827 1.00 96.17  ? 194 GLN E N   1 
ATOM   9455  C CA  . GLN D 2 178 ? 158.832 132.530 215.802 1.00 98.00  ? 194 GLN E CA  1 
ATOM   9456  C C   . GLN D 2 178 ? 159.458 132.454 217.190 1.00 100.67 ? 194 GLN E C   1 
ATOM   9457  O O   . GLN D 2 178 ? 158.801 132.759 218.192 1.00 101.35 ? 194 GLN E O   1 
ATOM   9458  C CB  . GLN D 2 178 ? 158.377 131.146 215.338 1.00 98.10  ? 194 GLN E CB  1 
ATOM   9459  C CG  . GLN D 2 178 ? 157.830 130.262 216.443 1.00 102.17 ? 194 GLN E CG  1 
ATOM   9460  C CD  . GLN D 2 178 ? 157.888 128.790 216.091 1.00 106.21 ? 194 GLN E CD  1 
ATOM   9461  O OE1 . GLN D 2 178 ? 157.904 128.421 214.917 1.00 106.33 ? 194 GLN E OE1 1 
ATOM   9462  N NE2 . GLN D 2 178 ? 157.922 127.939 217.110 1.00 106.45 ? 194 GLN E NE2 1 
ATOM   9463  N N   . ASN D 2 179 ? 160.724 132.055 217.270 1.00 101.12 ? 195 ASN E N   1 
ATOM   9464  C CA  . ASN D 2 179 ? 161.395 131.873 218.550 1.00 101.48 ? 195 ASN E CA  1 
ATOM   9465  C C   . ASN D 2 179 ? 162.210 133.084 218.991 1.00 103.19 ? 195 ASN E C   1 
ATOM   9466  O O   . ASN D 2 179 ? 162.838 133.031 220.053 1.00 105.47 ? 195 ASN E O   1 
ATOM   9467  C CB  . ASN D 2 179 ? 162.294 130.630 218.500 1.00 102.62 ? 195 ASN E CB  1 
ATOM   9468  C CG  . ASN D 2 179 ? 163.460 130.778 217.533 1.00 106.18 ? 195 ASN E CG  1 
ATOM   9469  O OD1 . ASN D 2 179 ? 163.601 131.792 216.849 1.00 105.43 ? 195 ASN E OD1 1 
ATOM   9470  N ND2 . ASN D 2 179 ? 164.306 129.756 217.475 1.00 106.75 ? 195 ASN E ND2 1 
ATOM   9471  N N   . THR D 2 180 ? 162.220 134.164 218.216 1.00 102.43 ? 196 THR E N   1 
ATOM   9472  C CA  . THR D 2 180 ? 163.027 135.319 218.578 1.00 103.73 ? 196 THR E CA  1 
ATOM   9473  C C   . THR D 2 180 ? 162.373 136.099 219.717 1.00 102.56 ? 196 THR E C   1 
ATOM   9474  O O   . THR D 2 180 ? 161.181 135.959 220.003 1.00 103.03 ? 196 THR E O   1 
ATOM   9475  C CB  . THR D 2 180 ? 163.254 136.229 217.368 1.00 101.76 ? 196 THR E CB  1 
ATOM   9476  O OG1 . THR D 2 180 ? 164.456 136.986 217.559 1.00 100.86 ? 196 THR E OG1 1 
ATOM   9477  C CG2 . THR D 2 180 ? 162.092 137.183 217.185 1.00 98.11  ? 196 THR E CG2 1 
ATOM   9478  N N   . GLU D 2 181 ? 163.185 136.925 220.380 1.00 102.11 ? 197 GLU E N   1 
ATOM   9479  C CA  . GLU D 2 181 ? 162.717 137.657 221.552 1.00 103.10 ? 197 GLU E CA  1 
ATOM   9480  C C   . GLU D 2 181 ? 161.794 138.810 221.175 1.00 103.15 ? 197 GLU E C   1 
ATOM   9481  O O   . GLU D 2 181 ? 160.783 139.042 221.846 1.00 105.23 ? 197 GLU E O   1 
ATOM   9482  C CB  . GLU D 2 181 ? 163.912 138.171 222.356 1.00 104.90 ? 197 GLU E CB  1 
ATOM   9483  C CG  . GLU D 2 181 ? 163.550 139.157 223.452 1.00 109.56 ? 197 GLU E CG  1 
ATOM   9484  C CD  . GLU D 2 181 ? 164.052 138.724 224.815 1.00 113.73 ? 197 GLU E CD  1 
ATOM   9485  O OE1 . GLU D 2 181 ? 163.836 139.469 225.794 1.00 115.54 ? 197 GLU E OE1 1 
ATOM   9486  O OE2 . GLU D 2 181 ? 164.663 137.639 224.908 1.00 112.16 ? 197 GLU E OE2 1 
ATOM   9487  N N   . GLU D 2 182 ? 162.122 139.540 220.105 1.00 101.97 ? 198 GLU E N   1 
ATOM   9488  C CA  . GLU D 2 182 ? 161.329 140.708 219.730 1.00 98.93  ? 198 GLU E CA  1 
ATOM   9489  C C   . GLU D 2 182 ? 159.905 140.318 219.355 1.00 100.30 ? 198 GLU E C   1 
ATOM   9490  O O   . GLU D 2 182 ? 158.950 141.034 219.680 1.00 100.92 ? 198 GLU E O   1 
ATOM   9491  C CB  . GLU D 2 182 ? 162.007 141.449 218.578 1.00 93.60  ? 198 GLU E CB  1 
ATOM   9492  C CG  . GLU D 2 182 ? 161.210 142.621 218.034 1.00 89.62  ? 198 GLU E CG  1 
ATOM   9493  C CD  . GLU D 2 182 ? 162.096 143.731 217.506 1.00 88.60  ? 198 GLU E CD  1 
ATOM   9494  O OE1 . GLU D 2 182 ? 162.598 143.603 216.370 1.00 85.94  ? 198 GLU E OE1 1 
ATOM   9495  O OE2 . GLU D 2 182 ? 162.292 144.731 218.228 1.00 90.12  ? 198 GLU E OE2 1 
ATOM   9496  N N   . PHE D 2 183 ? 159.741 139.187 218.665 1.00 98.06  ? 199 PHE E N   1 
ATOM   9497  C CA  . PHE D 2 183 ? 158.415 138.738 218.257 1.00 95.99  ? 199 PHE E CA  1 
ATOM   9498  C C   . PHE D 2 183 ? 157.530 138.385 219.445 1.00 99.74  ? 199 PHE E C   1 
ATOM   9499  O O   . PHE D 2 183 ? 156.301 138.447 219.326 1.00 100.06 ? 199 PHE E O   1 
ATOM   9500  C CB  . PHE D 2 183 ? 158.550 137.537 217.319 1.00 93.11  ? 199 PHE E CB  1 
ATOM   9501  C CG  . PHE D 2 183 ? 157.241 136.918 216.920 1.00 93.23  ? 199 PHE E CG  1 
ATOM   9502  C CD1 . PHE D 2 183 ? 156.480 137.469 215.904 1.00 91.26  ? 199 PHE E CD1 1 
ATOM   9503  C CD2 . PHE D 2 183 ? 156.781 135.773 217.549 1.00 94.54  ? 199 PHE E CD2 1 
ATOM   9504  C CE1 . PHE D 2 183 ? 155.280 136.897 215.532 1.00 90.63  ? 199 PHE E CE1 1 
ATOM   9505  C CE2 . PHE D 2 183 ? 155.583 135.198 217.181 1.00 95.63  ? 199 PHE E CE2 1 
ATOM   9506  C CZ  . PHE D 2 183 ? 154.832 135.760 216.172 1.00 93.94  ? 199 PHE E CZ  1 
ATOM   9507  N N   . LEU D 2 184 ? 158.121 138.018 220.585 1.00 101.14 ? 200 LEU E N   1 
ATOM   9508  C CA  . LEU D 2 184 ? 157.320 137.634 221.743 1.00 101.19 ? 200 LEU E CA  1 
ATOM   9509  C C   . LEU D 2 184 ? 156.496 138.803 222.270 1.00 105.19 ? 200 LEU E C   1 
ATOM   9510  O O   . LEU D 2 184 ? 155.327 138.630 222.632 1.00 109.74 ? 200 LEU E O   1 
ATOM   9511  C CB  . LEU D 2 184 ? 158.222 137.073 222.841 1.00 103.32 ? 200 LEU E CB  1 
ATOM   9512  C CG  . LEU D 2 184 ? 158.940 135.765 222.504 1.00 105.51 ? 200 LEU E CG  1 
ATOM   9513  C CD1 . LEU D 2 184 ? 159.926 135.396 223.601 1.00 104.61 ? 200 LEU E CD1 1 
ATOM   9514  C CD2 . LEU D 2 184 ? 157.935 134.646 222.279 1.00 104.99 ? 200 LEU E CD2 1 
ATOM   9515  N N   . HIS D 2 185 ? 157.083 140.000 222.320 1.00 102.90 ? 201 HIS E N   1 
ATOM   9516  C CA  . HIS D 2 185 ? 156.383 141.188 222.789 1.00 102.88 ? 201 HIS E CA  1 
ATOM   9517  C C   . HIS D 2 185 ? 155.714 141.964 221.660 1.00 100.90 ? 201 HIS E C   1 
ATOM   9518  O O   . HIS D 2 185 ? 155.513 143.177 221.789 1.00 101.53 ? 201 HIS E O   1 
ATOM   9519  C CB  . HIS D 2 185 ? 157.339 142.104 223.557 1.00 104.18 ? 201 HIS E CB  1 
ATOM   9520  C CG  . HIS D 2 185 ? 158.462 141.383 224.232 1.00 107.81 ? 201 HIS E CG  1 
ATOM   9521  N ND1 . HIS D 2 185 ? 158.383 140.926 225.530 1.00 113.65 ? 201 HIS E ND1 1 
ATOM   9522  C CD2 . HIS D 2 185 ? 159.693 141.035 223.786 1.00 105.59 ? 201 HIS E CD2 1 
ATOM   9523  C CE1 . HIS D 2 185 ? 159.516 140.328 225.854 1.00 111.77 ? 201 HIS E CE1 1 
ATOM   9524  N NE2 . HIS D 2 185 ? 160.327 140.382 224.814 1.00 109.47 ? 201 HIS E NE2 1 
ATOM   9525  N N   . LEU D 2 186 ? 155.371 141.298 220.564 1.00 100.31 ? 202 LEU E N   1 
ATOM   9526  C CA  . LEU D 2 186 ? 154.691 141.974 219.471 1.00 99.52  ? 202 LEU E CA  1 
ATOM   9527  C C   . LEU D 2 186 ? 153.273 142.357 219.890 1.00 100.53 ? 202 LEU E C   1 
ATOM   9528  O O   . LEU D 2 186 ? 152.622 141.615 220.633 1.00 103.32 ? 202 LEU E O   1 
ATOM   9529  C CB  . LEU D 2 186 ? 154.647 141.080 218.233 1.00 95.17  ? 202 LEU E CB  1 
ATOM   9530  C CG  . LEU D 2 186 ? 154.856 141.766 216.884 1.00 91.04  ? 202 LEU E CG  1 
ATOM   9531  C CD1 . LEU D 2 186 ? 156.316 142.135 216.693 1.00 89.18  ? 202 LEU E CD1 1 
ATOM   9532  C CD2 . LEU D 2 186 ? 154.372 140.876 215.754 1.00 87.97  ? 202 LEU E CD2 1 
ATOM   9533  N N   . PRO D 2 187 ? 152.772 143.506 219.444 1.00 98.99  ? 203 PRO E N   1 
ATOM   9534  C CA  . PRO D 2 187 ? 151.379 143.861 219.729 1.00 98.71  ? 203 PRO E CA  1 
ATOM   9535  C C   . PRO D 2 187 ? 150.413 142.917 219.031 1.00 98.67  ? 203 PRO E C   1 
ATOM   9536  O O   . PRO D 2 187 ? 150.743 142.280 218.028 1.00 98.97  ? 203 PRO E O   1 
ATOM   9537  C CB  . PRO D 2 187 ? 151.256 145.285 219.178 1.00 98.48  ? 203 PRO E CB  1 
ATOM   9538  C CG  . PRO D 2 187 ? 152.651 145.815 219.201 1.00 96.42  ? 203 PRO E CG  1 
ATOM   9539  C CD  . PRO D 2 187 ? 153.520 144.636 218.868 1.00 97.10  ? 203 PRO E CD  1 
ATOM   9540  N N   . HIS D 2 188 ? 149.202 142.827 219.587 1.00 99.27  ? 204 HIS E N   1 
ATOM   9541  C CA  . HIS D 2 188 ? 148.191 141.942 219.017 1.00 102.61 ? 204 HIS E CA  1 
ATOM   9542  C C   . HIS D 2 188 ? 147.813 142.367 217.603 1.00 100.23 ? 204 HIS E C   1 
ATOM   9543  O O   . HIS D 2 188 ? 147.637 141.521 216.719 1.00 98.67  ? 204 HIS E O   1 
ATOM   9544  C CB  . HIS D 2 188 ? 146.954 141.910 219.912 1.00 105.19 ? 204 HIS E CB  1 
ATOM   9545  C CG  . HIS D 2 188 ? 145.850 141.047 219.385 1.00 108.57 ? 204 HIS E CG  1 
ATOM   9546  N ND1 . HIS D 2 188 ? 146.082 139.942 218.595 1.00 109.81 ? 204 HIS E ND1 1 
ATOM   9547  C CD2 . HIS D 2 188 ? 144.506 141.132 219.528 1.00 110.31 ? 204 HIS E CD2 1 
ATOM   9548  C CE1 . HIS D 2 188 ? 144.929 139.380 218.278 1.00 110.83 ? 204 HIS E CE1 1 
ATOM   9549  N NE2 . HIS D 2 188 ? 143.957 140.083 218.831 1.00 111.15 ? 204 HIS E NE2 1 
ATOM   9550  N N   . ARG D 2 189 ? 147.673 143.674 217.374 1.00 98.11  ? 205 ARG E N   1 
ATOM   9551  C CA  . ARG D 2 189 ? 147.311 144.157 216.045 1.00 95.56  ? 205 ARG E CA  1 
ATOM   9552  C C   . ARG D 2 189 ? 148.404 143.851 215.028 1.00 93.71  ? 205 ARG E C   1 
ATOM   9553  O O   . ARG D 2 189 ? 148.113 143.459 213.892 1.00 91.83  ? 205 ARG E O   1 
ATOM   9554  C CB  . ARG D 2 189 ? 147.015 145.657 216.100 1.00 95.22  ? 205 ARG E CB  1 
ATOM   9555  C CG  . ARG D 2 189 ? 147.162 146.382 214.774 1.00 95.47  ? 205 ARG E CG  1 
ATOM   9556  C CD  . ARG D 2 189 ? 147.302 147.880 214.988 1.00 97.21  ? 205 ARG E CD  1 
ATOM   9557  N NE  . ARG D 2 189 ? 148.214 148.194 216.081 1.00 97.51  ? 205 ARG E NE  1 
ATOM   9558  C CZ  . ARG D 2 189 ? 148.933 149.305 216.160 1.00 93.56  ? 205 ARG E CZ  1 
ATOM   9559  N NH1 . ARG D 2 189 ? 148.872 150.236 215.223 1.00 90.94  ? 205 ARG E NH1 1 
ATOM   9560  N NH2 . ARG D 2 189 ? 149.733 149.486 217.207 1.00 89.99  ? 205 ARG E NH2 1 
ATOM   9561  N N   . LEU D 2 190 ? 149.671 144.017 215.419 1.00 93.78  ? 206 LEU E N   1 
ATOM   9562  C CA  . LEU D 2 190 ? 150.771 143.702 214.514 1.00 91.80  ? 206 LEU E CA  1 
ATOM   9563  C C   . LEU D 2 190 ? 150.793 142.218 214.167 1.00 91.04  ? 206 LEU E C   1 
ATOM   9564  O O   . LEU D 2 190 ? 150.998 141.845 213.005 1.00 89.21  ? 206 LEU E O   1 
ATOM   9565  C CB  . LEU D 2 190 ? 152.101 144.125 215.138 1.00 89.83  ? 206 LEU E CB  1 
ATOM   9566  C CG  . LEU D 2 190 ? 152.528 145.585 214.963 1.00 87.41  ? 206 LEU E CG  1 
ATOM   9567  C CD1 . LEU D 2 190 ? 154.034 145.722 215.102 1.00 83.75  ? 206 LEU E CD1 1 
ATOM   9568  C CD2 . LEU D 2 190 ? 152.058 146.143 213.634 1.00 81.10  ? 206 LEU E CD2 1 
ATOM   9569  N N   . LEU D 2 191 ? 150.582 141.355 215.164 1.00 93.13  ? 207 LEU E N   1 
ATOM   9570  C CA  . LEU D 2 191 ? 150.558 139.919 214.909 1.00 88.51  ? 207 LEU E CA  1 
ATOM   9571  C C   . LEU D 2 191 ? 149.387 139.538 214.012 1.00 87.39  ? 207 LEU E C   1 
ATOM   9572  O O   . LEU D 2 191 ? 149.524 138.676 213.135 1.00 87.39  ? 207 LEU E O   1 
ATOM   9573  C CB  . LEU D 2 191 ? 150.489 139.152 216.227 1.00 89.68  ? 207 LEU E CB  1 
ATOM   9574  C CG  . LEU D 2 191 ? 150.364 137.638 216.068 1.00 92.59  ? 207 LEU E CG  1 
ATOM   9575  C CD1 . LEU D 2 191 ? 151.649 137.074 215.499 1.00 91.52  ? 207 LEU E CD1 1 
ATOM   9576  C CD2 . LEU D 2 191 ? 150.023 136.977 217.384 1.00 98.82  ? 207 LEU E CD2 1 
ATOM   9577  N N   . THR D 2 192 ? 148.226 140.159 214.227 1.00 89.44  ? 208 THR E N   1 
ATOM   9578  C CA  . THR D 2 192 ? 147.079 139.902 213.363 1.00 90.42  ? 208 THR E CA  1 
ATOM   9579  C C   . THR D 2 192 ? 147.368 140.338 211.933 1.00 88.78  ? 208 THR E C   1 
ATOM   9580  O O   . THR D 2 192 ? 147.004 139.643 210.978 1.00 89.56  ? 208 THR E O   1 
ATOM   9581  C CB  . THR D 2 192 ? 145.841 140.613 213.914 1.00 93.07  ? 208 THR E CB  1 
ATOM   9582  O OG1 . THR D 2 192 ? 145.258 139.820 214.954 1.00 97.58  ? 208 THR E OG1 1 
ATOM   9583  C CG2 . THR D 2 192 ? 144.806 140.839 212.820 1.00 86.56  ? 208 THR E CG2 1 
ATOM   9584  N N   . ASP D 2 193 ? 148.037 141.481 211.766 1.00 86.74  ? 209 ASP E N   1 
ATOM   9585  C CA  . ASP D 2 193 ? 148.401 141.938 210.429 1.00 83.34  ? 209 ASP E CA  1 
ATOM   9586  C C   . ASP D 2 193 ? 149.381 140.978 209.765 1.00 83.92  ? 209 ASP E C   1 
ATOM   9587  O O   . ASP D 2 193 ? 149.305 140.738 208.555 1.00 83.17  ? 209 ASP E O   1 
ATOM   9588  C CB  . ASP D 2 193 ? 148.992 143.344 210.500 1.00 83.57  ? 209 ASP E CB  1 
ATOM   9589  C CG  . ASP D 2 193 ? 148.005 144.412 210.077 1.00 90.00  ? 209 ASP E CG  1 
ATOM   9590  O OD1 . ASP D 2 193 ? 147.399 144.266 208.996 1.00 90.24  ? 209 ASP E OD1 1 
ATOM   9591  O OD2 . ASP D 2 193 ? 147.837 145.398 210.826 1.00 90.01  ? 209 ASP E OD2 1 
ATOM   9592  N N   . ILE D 2 194 ? 150.317 140.430 210.541 1.00 86.32  ? 210 ILE E N   1 
ATOM   9593  C CA  . ILE D 2 194 ? 151.287 139.488 209.985 1.00 82.67  ? 210 ILE E CA  1 
ATOM   9594  C C   . ILE D 2 194 ? 150.593 138.203 209.547 1.00 84.32  ? 210 ILE E C   1 
ATOM   9595  O O   . ILE D 2 194 ? 150.794 137.715 208.429 1.00 85.94  ? 210 ILE E O   1 
ATOM   9596  C CB  . ILE D 2 194 ? 152.403 139.201 211.006 1.00 80.87  ? 210 ILE E CB  1 
ATOM   9597  C CG1 . ILE D 2 194 ? 153.351 140.393 211.120 1.00 76.70  ? 210 ILE E CG1 1 
ATOM   9598  C CG2 . ILE D 2 194 ? 153.173 137.948 210.620 1.00 78.45  ? 210 ILE E CG2 1 
ATOM   9599  C CD1 . ILE D 2 194 ? 154.493 140.158 212.078 1.00 75.89  ? 210 ILE E CD1 1 
ATOM   9600  N N   . ILE D 2 195 ? 149.763 137.635 210.426 1.00 85.10  ? 211 ILE E N   1 
ATOM   9601  C CA  . ILE D 2 195 ? 149.161 136.330 210.157 1.00 86.52  ? 211 ILE E CA  1 
ATOM   9602  C C   . ILE D 2 195 ? 148.098 136.426 209.066 1.00 87.34  ? 211 ILE E C   1 
ATOM   9603  O O   . ILE D 2 195 ? 148.027 135.570 208.177 1.00 89.06  ? 211 ILE E O   1 
ATOM   9604  C CB  . ILE D 2 195 ? 148.602 135.725 211.459 1.00 85.14  ? 211 ILE E CB  1 
ATOM   9605  C CG1 . ILE D 2 195 ? 149.583 134.700 212.029 1.00 87.77  ? 211 ILE E CG1 1 
ATOM   9606  C CG2 . ILE D 2 195 ? 147.245 135.078 211.230 1.00 89.26  ? 211 ILE E CG2 1 
ATOM   9607  C CD1 . ILE D 2 195 ? 150.884 135.290 212.503 1.00 86.08  ? 211 ILE E CD1 1 
ATOM   9608  N N   . SER D 2 196 ? 147.261 137.466 209.108 1.00 88.84  ? 212 SER E N   1 
ATOM   9609  C CA  . SER D 2 196 ? 146.130 137.555 208.192 1.00 90.56  ? 212 SER E CA  1 
ATOM   9610  C C   . SER D 2 196 ? 146.555 137.762 206.745 1.00 92.80  ? 212 SER E C   1 
ATOM   9611  O O   . SER D 2 196 ? 145.732 137.582 205.841 1.00 95.19  ? 212 SER E O   1 
ATOM   9612  C CB  . SER D 2 196 ? 145.196 138.686 208.622 1.00 91.74  ? 212 SER E CB  1 
ATOM   9613  O OG  . SER D 2 196 ? 144.568 139.280 207.499 1.00 96.28  ? 212 SER E OG  1 
ATOM   9614  N N   . ASP D 2 197 ? 147.810 138.143 206.503 1.00 92.41  ? 213 ASP E N   1 
ATOM   9615  C CA  . ASP D 2 197 ? 148.261 138.351 205.131 1.00 95.14  ? 213 ASP E CA  1 
ATOM   9616  C C   . ASP D 2 197 ? 148.342 137.040 204.359 1.00 94.58  ? 213 ASP E C   1 
ATOM   9617  O O   . ASP D 2 197 ? 148.096 137.020 203.148 1.00 90.97  ? 213 ASP E O   1 
ATOM   9618  C CB  . ASP D 2 197 ? 149.616 139.057 205.124 1.00 91.02  ? 213 ASP E CB  1 
ATOM   9619  C CG  . ASP D 2 197 ? 149.733 140.079 204.012 1.00 90.07  ? 213 ASP E CG  1 
ATOM   9620  O OD1 . ASP D 2 197 ? 148.839 140.945 203.904 1.00 88.69  ? 213 ASP E OD1 1 
ATOM   9621  O OD2 . ASP D 2 197 ? 150.715 140.013 203.243 1.00 91.18  ? 213 ASP E OD2 1 
ATOM   9622  N N   . GLY D 2 198 ? 148.678 135.946 205.034 1.00 94.51  ? 214 GLY E N   1 
ATOM   9623  C CA  . GLY D 2 198 ? 148.815 134.661 204.378 1.00 97.64  ? 214 GLY E CA  1 
ATOM   9624  C C   . GLY D 2 198 ? 150.254 134.199 204.317 1.00 94.11  ? 214 GLY E C   1 
ATOM   9625  O O   . GLY D 2 198 ? 151.022 134.645 203.460 1.00 95.28  ? 214 GLY E O   1 
ATOM   9626  N N   . VAL D 2 199 ? 150.629 133.296 205.216 1.00 92.96  ? 215 VAL E N   1 
ATOM   9627  C CA  . VAL D 2 199 ? 152.015 132.854 205.337 1.00 95.01  ? 215 VAL E CA  1 
ATOM   9628  C C   . VAL D 2 199 ? 152.185 131.523 204.613 1.00 98.68  ? 215 VAL E C   1 
ATOM   9629  O O   . VAL D 2 199 ? 151.203 130.789 204.427 1.00 104.32 ? 215 VAL E O   1 
ATOM   9630  C CB  . VAL D 2 199 ? 152.433 132.750 206.813 1.00 92.46  ? 215 VAL E CB  1 
ATOM   9631  C CG1 . VAL D 2 199 ? 151.841 133.900 207.611 1.00 86.79  ? 215 VAL E CG1 1 
ATOM   9632  C CG2 . VAL D 2 199 ? 152.011 131.418 207.397 1.00 98.90  ? 215 VAL E CG2 1 
ATOM   9633  N N   . PRO D 2 200 ? 153.391 131.184 204.165 1.00 99.18  ? 216 PRO E N   1 
ATOM   9634  C CA  . PRO D 2 200 ? 153.605 129.865 203.562 1.00 103.17 ? 216 PRO E CA  1 
ATOM   9635  C C   . PRO D 2 200 ? 153.446 128.752 204.585 1.00 104.11 ? 216 PRO E C   1 
ATOM   9636  O O   . PRO D 2 200 ? 153.626 128.947 205.789 1.00 102.94 ? 216 PRO E O   1 
ATOM   9637  C CB  . PRO D 2 200 ? 155.046 129.939 203.041 1.00 102.68 ? 216 PRO E CB  1 
ATOM   9638  C CG  . PRO D 2 200 ? 155.346 131.402 202.938 1.00 97.49  ? 216 PRO E CG  1 
ATOM   9639  C CD  . PRO D 2 200 ? 154.580 132.043 204.049 1.00 94.61  ? 216 PRO E CD  1 
ATOM   9640  N N   . CYS D 2 201 ? 153.097 127.565 204.083 1.00 105.25 ? 217 CYS E N   1 
ATOM   9641  C CA  . CYS D 2 201 ? 152.869 126.418 204.954 1.00 106.11 ? 217 CYS E CA  1 
ATOM   9642  C C   . CYS D 2 201 ? 154.140 125.943 205.646 1.00 104.79 ? 217 CYS E C   1 
ATOM   9643  O O   . CYS D 2 201 ? 154.053 125.255 206.668 1.00 104.14 ? 217 CYS E O   1 
ATOM   9644  C CB  . CYS D 2 201 ? 152.256 125.267 204.155 1.00 110.88 ? 217 CYS E CB  1 
ATOM   9645  S SG  . CYS D 2 201 ? 150.984 125.773 202.974 1.00 125.36 ? 217 CYS E SG  1 
ATOM   9646  N N   . SER D 2 202 ? 155.315 126.287 205.114 1.00 103.95 ? 218 SER E N   1 
ATOM   9647  C CA  . SER D 2 202 ? 156.565 125.847 205.724 1.00 101.97 ? 218 SER E CA  1 
ATOM   9648  C C   . SER D 2 202 ? 156.899 126.620 206.992 1.00 99.48  ? 218 SER E C   1 
ATOM   9649  O O   . SER D 2 202 ? 157.733 126.160 207.779 1.00 96.58  ? 218 SER E O   1 
ATOM   9650  C CB  . SER D 2 202 ? 157.714 125.977 204.724 1.00 98.82  ? 218 SER E CB  1 
ATOM   9651  O OG  . SER D 2 202 ? 158.906 125.416 205.244 1.00 97.65  ? 218 SER E OG  1 
ATOM   9652  N N   . GLN D 2 203 ? 156.274 127.778 207.207 1.00 101.14 ? 219 GLN E N   1 
ATOM   9653  C CA  . GLN D 2 203 ? 156.565 128.583 208.386 1.00 101.22 ? 219 GLN E CA  1 
ATOM   9654  C C   . GLN D 2 203 ? 155.923 128.034 209.651 1.00 103.97 ? 219 GLN E C   1 
ATOM   9655  O O   . GLN D 2 203 ? 156.383 128.363 210.750 1.00 101.08 ? 219 GLN E O   1 
ATOM   9656  C CB  . GLN D 2 203 ? 156.102 130.025 208.167 1.00 98.07  ? 219 GLN E CB  1 
ATOM   9657  C CG  . GLN D 2 203 ? 156.554 130.630 206.852 1.00 94.46  ? 219 GLN E CG  1 
ATOM   9658  C CD  . GLN D 2 203 ? 158.006 130.333 206.550 1.00 92.57  ? 219 GLN E CD  1 
ATOM   9659  O OE1 . GLN D 2 203 ? 158.883 130.537 207.389 1.00 90.02  ? 219 GLN E OE1 1 
ATOM   9660  N NE2 . GLN D 2 203 ? 158.270 129.846 205.344 1.00 95.97  ? 219 GLN E NE2 1 
ATOM   9661  N N   . ASN D 2 204 ? 154.881 127.211 209.519 1.00 106.69 ? 220 ASN E N   1 
ATOM   9662  C CA  . ASN D 2 204 ? 154.130 126.672 210.647 1.00 107.60 ? 220 ASN E CA  1 
ATOM   9663  C C   . ASN D 2 204 ? 153.597 127.809 211.511 1.00 107.89 ? 220 ASN E C   1 
ATOM   9664  O O   . ASN D 2 204 ? 154.069 128.008 212.637 1.00 108.93 ? 220 ASN E O   1 
ATOM   9665  C CB  . ASN D 2 204 ? 154.996 125.721 211.476 1.00 108.43 ? 220 ASN E CB  1 
ATOM   9666  C CG  . ASN D 2 204 ? 154.712 124.264 211.173 1.00 110.51 ? 220 ASN E CG  1 
ATOM   9667  O OD1 . ASN D 2 204 ? 153.982 123.945 210.235 1.00 110.25 ? 220 ASN E OD1 1 
ATOM   9668  N ND2 . ASN D 2 204 ? 155.294 123.371 211.964 1.00 111.54 ? 220 ASN E ND2 1 
ATOM   9669  N N   . PRO D 2 205 ? 152.632 128.587 211.013 1.00 105.29 ? 221 PRO E N   1 
ATOM   9670  C CA  . PRO D 2 205 ? 152.087 129.687 211.825 1.00 105.91 ? 221 PRO E CA  1 
ATOM   9671  C C   . PRO D 2 205 ? 151.401 129.221 213.095 1.00 108.90 ? 221 PRO E C   1 
ATOM   9672  O O   . PRO D 2 205 ? 151.329 129.986 214.067 1.00 109.56 ? 221 PRO E O   1 
ATOM   9673  C CB  . PRO D 2 205 ? 151.100 130.365 210.867 1.00 103.83 ? 221 PRO E CB  1 
ATOM   9674  C CG  . PRO D 2 205 ? 150.700 129.281 209.927 1.00 105.39 ? 221 PRO E CG  1 
ATOM   9675  C CD  . PRO D 2 205 ? 151.928 128.449 209.727 1.00 103.85 ? 221 PRO E CD  1 
ATOM   9676  N N   . THR D 2 206 ? 150.880 127.991 213.112 1.00 109.66 ? 222 THR E N   1 
ATOM   9677  C CA  . THR D 2 206 ? 150.198 127.492 214.301 1.00 108.14 ? 222 THR E CA  1 
ATOM   9678  C C   . THR D 2 206 ? 151.149 127.419 215.489 1.00 110.20 ? 222 THR E C   1 
ATOM   9679  O O   . THR D 2 206 ? 150.796 127.825 216.602 1.00 112.96 ? 222 THR E O   1 
ATOM   9680  C CB  . THR D 2 206 ? 149.582 126.122 214.012 1.00 109.35 ? 222 THR E CB  1 
ATOM   9681  O OG1 . THR D 2 206 ? 148.334 126.295 213.330 1.00 110.41 ? 222 THR E OG1 1 
ATOM   9682  C CG2 . THR D 2 206 ? 149.342 125.350 215.302 1.00 110.48 ? 222 THR E CG2 1 
ATOM   9683  N N   . GLU D 2 207 ? 152.370 126.926 215.268 1.00 110.66 ? 223 GLU E N   1 
ATOM   9684  C CA  . GLU D 2 207 ? 153.353 126.888 216.345 1.00 110.10 ? 223 GLU E CA  1 
ATOM   9685  C C   . GLU D 2 207 ? 153.706 128.293 216.817 1.00 110.83 ? 223 GLU E C   1 
ATOM   9686  O O   . GLU D 2 207 ? 153.892 128.524 218.018 1.00 110.96 ? 223 GLU E O   1 
ATOM   9687  C CB  . GLU D 2 207 ? 154.607 126.143 215.888 1.00 109.72 ? 223 GLU E CB  1 
ATOM   9688  C CG  . GLU D 2 207 ? 154.339 124.745 215.360 1.00 111.58 ? 223 GLU E CG  1 
ATOM   9689  C CD  . GLU D 2 207 ? 155.613 123.996 215.024 1.00 116.05 ? 223 GLU E CD  1 
ATOM   9690  O OE1 . GLU D 2 207 ? 156.708 124.567 215.210 1.00 116.00 ? 223 GLU E OE1 1 
ATOM   9691  O OE2 . GLU D 2 207 ? 155.521 122.835 214.573 1.00 117.68 ? 223 GLU E OE2 1 
ATOM   9692  N N   . ALA D 2 208 ? 153.802 129.246 215.887 1.00 109.41 ? 224 ALA E N   1 
ATOM   9693  C CA  . ALA D 2 208 ? 154.141 130.616 216.260 1.00 108.42 ? 224 ALA E CA  1 
ATOM   9694  C C   . ALA D 2 208 ? 153.056 131.239 217.131 1.00 109.88 ? 224 ALA E C   1 
ATOM   9695  O O   . ALA D 2 208 ? 153.349 131.850 218.167 1.00 110.49 ? 224 ALA E O   1 
ATOM   9696  C CB  . ALA D 2 208 ? 154.373 131.456 215.004 1.00 105.47 ? 224 ALA E CB  1 
ATOM   9697  N N   . ILE D 2 209 ? 151.791 131.095 216.727 1.00 110.39 ? 225 ILE E N   1 
ATOM   9698  C CA  . ILE D 2 209 ? 150.711 131.661 217.531 1.00 109.86 ? 225 ILE E CA  1 
ATOM   9699  C C   . ILE D 2 209 ? 150.592 130.929 218.862 1.00 112.45 ? 225 ILE E C   1 
ATOM   9700  O O   . ILE D 2 209 ? 150.271 131.545 219.887 1.00 115.27 ? 225 ILE E O   1 
ATOM   9701  C CB  . ILE D 2 209 ? 149.380 131.667 216.752 1.00 108.32 ? 225 ILE E CB  1 
ATOM   9702  C CG1 . ILE D 2 209 ? 148.841 130.251 216.553 1.00 112.24 ? 225 ILE E CG1 1 
ATOM   9703  C CG2 . ILE D 2 209 ? 149.545 132.370 215.413 1.00 105.16 ? 225 ILE E CG2 1 
ATOM   9704  C CD1 . ILE D 2 209 ? 147.341 130.190 216.380 1.00 114.87 ? 225 ILE E CD1 1 
ATOM   9705  N N   . GLU D 2 210 ? 150.856 129.618 218.884 1.00 113.35 ? 226 GLU E N   1 
ATOM   9706  C CA  . GLU D 2 210 ? 150.846 128.886 220.145 1.00 114.00 ? 226 GLU E CA  1 
ATOM   9707  C C   . GLU D 2 210 ? 151.924 129.402 221.090 1.00 115.82 ? 226 GLU E C   1 
ATOM   9708  O O   . GLU D 2 210 ? 151.676 129.576 222.287 1.00 117.83 ? 226 GLU E O   1 
ATOM   9709  C CB  . GLU D 2 210 ? 151.032 127.392 219.884 1.00 112.98 ? 226 GLU E CB  1 
ATOM   9710  C CG  . GLU D 2 210 ? 150.579 126.497 221.025 1.00 115.15 ? 226 GLU E CG  1 
ATOM   9711  C CD  . GLU D 2 210 ? 149.218 126.884 221.566 1.00 120.66 ? 226 GLU E CD  1 
ATOM   9712  O OE1 . GLU D 2 210 ? 148.249 126.910 220.779 1.00 122.32 ? 226 GLU E OE1 1 
ATOM   9713  O OE2 . GLU D 2 210 ? 149.117 127.159 222.781 1.00 120.91 ? 226 GLU E OE2 1 
ATOM   9714  N N   . ALA D 2 211 ? 153.126 129.656 220.568 1.00 114.00 ? 227 ALA E N   1 
ATOM   9715  C CA  . ALA D 2 211 ? 154.194 130.201 221.401 1.00 113.55 ? 227 ALA E CA  1 
ATOM   9716  C C   . ALA D 2 211 ? 153.846 131.597 221.899 1.00 114.42 ? 227 ALA E C   1 
ATOM   9717  O O   . ALA D 2 211 ? 154.110 131.936 223.060 1.00 117.13 ? 227 ALA E O   1 
ATOM   9718  C CB  . ALA D 2 211 ? 155.510 130.218 220.624 1.00 110.22 ? 227 ALA E CB  1 
ATOM   9719  N N   . TRP D 2 212 ? 153.252 132.424 221.034 1.00 112.75 ? 228 TRP E N   1 
ATOM   9720  C CA  . TRP D 2 212 ? 152.860 133.766 221.453 1.00 114.48 ? 228 TRP E CA  1 
ATOM   9721  C C   . TRP D 2 212 ? 151.817 133.711 222.562 1.00 116.69 ? 228 TRP E C   1 
ATOM   9722  O O   . TRP D 2 212 ? 151.880 134.487 223.523 1.00 117.54 ? 228 TRP E O   1 
ATOM   9723  C CB  . TRP D 2 212 ? 152.329 134.560 220.261 1.00 112.34 ? 228 TRP E CB  1 
ATOM   9724  C CG  . TRP D 2 212 ? 152.239 136.033 220.523 1.00 110.93 ? 228 TRP E CG  1 
ATOM   9725  C CD1 . TRP D 2 212 ? 153.278 136.912 220.622 1.00 107.49 ? 228 TRP E CD1 1 
ATOM   9726  C CD2 . TRP D 2 212 ? 151.046 136.798 220.735 1.00 110.88 ? 228 TRP E CD2 1 
ATOM   9727  N NE1 . TRP D 2 212 ? 152.807 138.177 220.873 1.00 106.60 ? 228 TRP E NE1 1 
ATOM   9728  C CE2 . TRP D 2 212 ? 151.440 138.134 220.948 1.00 110.85 ? 228 TRP E CE2 1 
ATOM   9729  C CE3 . TRP D 2 212 ? 149.684 136.484 220.763 1.00 109.88 ? 228 TRP E CE3 1 
ATOM   9730  C CZ2 . TRP D 2 212 ? 150.521 139.154 221.184 1.00 110.24 ? 228 TRP E CZ2 1 
ATOM   9731  C CZ3 . TRP D 2 212 ? 148.774 137.498 220.995 1.00 111.29 ? 228 TRP E CZ3 1 
ATOM   9732  C CH2 . TRP D 2 212 ? 149.197 138.816 221.204 1.00 110.07 ? 228 TRP E CH2 1 
ATOM   9733  N N   . ILE D 2 213 ? 150.845 132.803 222.444 1.00 116.21 ? 229 ILE E N   1 
ATOM   9734  C CA  . ILE D 2 213 ? 149.845 132.642 223.497 1.00 117.00 ? 229 ILE E CA  1 
ATOM   9735  C C   . ILE D 2 213 ? 150.499 132.144 224.780 1.00 119.16 ? 229 ILE E C   1 
ATOM   9736  O O   . ILE D 2 213 ? 150.191 132.624 225.878 1.00 121.28 ? 229 ILE E O   1 
ATOM   9737  C CB  . ILE D 2 213 ? 148.714 131.706 223.025 1.00 115.81 ? 229 ILE E CB  1 
ATOM   9738  C CG1 . ILE D 2 213 ? 147.503 132.515 222.554 1.00 113.84 ? 229 ILE E CG1 1 
ATOM   9739  C CG2 . ILE D 2 213 ? 148.295 130.745 224.128 1.00 117.67 ? 229 ILE E CG2 1 
ATOM   9740  C CD1 . ILE D 2 213 ? 147.820 133.553 221.509 1.00 115.07 ? 229 ILE E CD1 1 
ATOM   9741  N N   . ASN D 2 214 ? 151.422 131.185 224.663 1.00 117.88 ? 230 ASN E N   1 
ATOM   9742  C CA  . ASN D 2 214 ? 152.087 130.632 225.837 1.00 119.58 ? 230 ASN E CA  1 
ATOM   9743  C C   . ASN D 2 214 ? 152.990 131.645 226.525 1.00 118.40 ? 230 ASN E C   1 
ATOM   9744  O O   . ASN D 2 214 ? 153.293 131.476 227.711 1.00 118.09 ? 230 ASN E O   1 
ATOM   9745  C CB  . ASN D 2 214 ? 152.898 129.395 225.450 1.00 120.62 ? 230 ASN E CB  1 
ATOM   9746  C CG  . ASN D 2 214 ? 152.023 128.238 225.011 1.00 121.80 ? 230 ASN E CG  1 
ATOM   9747  O OD1 . ASN D 2 214 ? 150.844 128.171 225.355 1.00 121.54 ? 230 ASN E OD1 1 
ATOM   9748  N ND2 . ASN D 2 214 ? 152.599 127.319 224.245 1.00 121.26 ? 230 ASN E ND2 1 
ATOM   9749  N N   . PHE D 2 215 ? 153.436 132.681 225.811 1.00 117.41 ? 231 PHE E N   1 
ATOM   9750  C CA  . PHE D 2 215 ? 154.249 133.711 226.452 1.00 118.16 ? 231 PHE E CA  1 
ATOM   9751  C C   . PHE D 2 215 ? 153.471 134.419 227.555 1.00 121.16 ? 231 PHE E C   1 
ATOM   9752  O O   . PHE D 2 215 ? 154.007 134.668 228.641 1.00 120.37 ? 231 PHE E O   1 
ATOM   9753  C CB  . PHE D 2 215 ? 154.742 134.719 225.414 1.00 115.35 ? 231 PHE E CB  1 
ATOM   9754  C CG  . PHE D 2 215 ? 155.835 135.617 225.917 1.00 113.88 ? 231 PHE E CG  1 
ATOM   9755  C CD1 . PHE D 2 215 ? 157.033 135.087 226.368 1.00 111.98 ? 231 PHE E CD1 1 
ATOM   9756  C CD2 . PHE D 2 215 ? 155.664 136.991 225.948 1.00 112.57 ? 231 PHE E CD2 1 
ATOM   9757  C CE1 . PHE D 2 215 ? 158.041 135.909 226.833 1.00 110.23 ? 231 PHE E CE1 1 
ATOM   9758  C CE2 . PHE D 2 215 ? 156.668 137.818 226.414 1.00 108.32 ? 231 PHE E CE2 1 
ATOM   9759  C CZ  . PHE D 2 215 ? 157.858 137.276 226.856 1.00 108.72 ? 231 PHE E CZ  1 
ATOM   9760  N N   . ASN D 2 216 ? 152.204 134.752 227.296 1.00 121.99 ? 232 ASN E N   1 
ATOM   9761  C CA  . ASN D 2 216 ? 151.328 135.378 228.292 1.00 123.62 ? 232 ASN E CA  1 
ATOM   9762  C C   . ASN D 2 216 ? 149.928 134.800 228.095 1.00 125.19 ? 232 ASN E C   1 
ATOM   9763  O O   . ASN D 2 216 ? 149.136 135.314 227.301 1.00 124.95 ? 232 ASN E O   1 
ATOM   9764  C CB  . ASN D 2 216 ? 151.337 136.896 228.164 1.00 122.62 ? 232 ASN E CB  1 
ATOM   9765  C CG  . ASN D 2 216 ? 151.215 137.592 229.504 1.00 126.05 ? 232 ASN E CG  1 
ATOM   9766  O OD1 . ASN D 2 216 ? 150.958 136.956 230.525 1.00 127.43 ? 232 ASN E OD1 1 
ATOM   9767  N ND2 . ASN D 2 216 ? 151.399 138.907 229.506 1.00 126.85 ? 232 ASN E ND2 1 
ATOM   9768  N N   . LYS D 2 217 ? 149.628 133.728 228.830 1.00 125.95 ? 233 LYS E N   1 
ATOM   9769  C CA  . LYS D 2 217 ? 148.343 133.053 228.695 1.00 126.50 ? 233 LYS E CA  1 
ATOM   9770  C C   . LYS D 2 217 ? 147.211 133.778 229.408 1.00 129.29 ? 233 LYS E C   1 
ATOM   9771  O O   . LYS D 2 217 ? 146.042 133.526 229.099 1.00 127.67 ? 233 LYS E O   1 
ATOM   9772  C CB  . LYS D 2 217 ? 148.446 131.622 229.228 1.00 124.25 ? 233 LYS E CB  1 
ATOM   9773  C CG  . LYS D 2 217 ? 149.262 130.687 228.351 1.00 122.35 ? 233 LYS E CG  1 
ATOM   9774  C CD  . LYS D 2 217 ? 148.970 129.229 228.669 1.00 123.57 ? 233 LYS E CD  1 
ATOM   9775  C CE  . LYS D 2 217 ? 147.535 128.862 228.326 1.00 122.33 ? 233 LYS E CE  1 
ATOM   9776  N NZ  . LYS D 2 217 ? 147.146 129.341 226.971 1.00 122.28 ? 233 LYS E NZ  1 
ATOM   9777  N N   . GLU D 2 218 ? 147.527 134.666 230.353 1.00 131.05 ? 234 GLU E N   1 
ATOM   9778  C CA  . GLU D 2 218 ? 146.485 135.293 231.160 1.00 128.67 ? 234 GLU E CA  1 
ATOM   9779  C C   . GLU D 2 218 ? 145.673 136.297 230.349 1.00 128.11 ? 234 GLU E C   1 
ATOM   9780  O O   . GLU D 2 218 ? 144.437 136.295 230.401 1.00 128.04 ? 234 GLU E O   1 
ATOM   9781  C CB  . GLU D 2 218 ? 147.108 135.964 232.384 1.00 126.60 ? 234 GLU E CB  1 
ATOM   9782  C CG  . GLU D 2 218 ? 147.513 134.993 233.484 1.00 126.77 ? 234 GLU E CG  1 
ATOM   9783  C CD  . GLU D 2 218 ? 148.861 134.343 233.229 1.00 127.76 ? 234 GLU E CD  1 
ATOM   9784  O OE1 . GLU D 2 218 ? 149.479 134.635 232.183 1.00 127.66 ? 234 GLU E OE1 1 
ATOM   9785  O OE2 . GLU D 2 218 ? 149.302 133.539 234.077 1.00 125.77 ? 234 GLU E OE2 1 
ATOM   9786  N N   . GLU D 2 219 ? 146.347 137.162 229.590 1.00 128.39 ? 235 GLU E N   1 
ATOM   9787  C CA  . GLU D 2 219 ? 145.668 138.239 228.881 1.00 129.08 ? 235 GLU E CA  1 
ATOM   9788  C C   . GLU D 2 219 ? 145.467 137.966 227.397 1.00 127.93 ? 235 GLU E C   1 
ATOM   9789  O O   . GLU D 2 219 ? 144.564 138.558 226.795 1.00 125.06 ? 235 GLU E O   1 
ATOM   9790  C CB  . GLU D 2 219 ? 146.440 139.554 229.049 1.00 125.68 ? 235 GLU E CB  1 
ATOM   9791  C CG  . GLU D 2 219 ? 147.816 139.560 228.407 1.00 124.40 ? 235 GLU E CG  1 
ATOM   9792  C CD  . GLU D 2 219 ? 148.528 140.888 228.572 1.00 123.81 ? 235 GLU E CD  1 
ATOM   9793  O OE1 . GLU D 2 219 ? 147.956 141.796 229.211 1.00 120.15 ? 235 GLU E OE1 1 
ATOM   9794  O OE2 . GLU D 2 219 ? 149.661 141.025 228.063 1.00 125.36 ? 235 GLU E OE2 1 
ATOM   9795  N N   . ARG D 2 220 ? 146.273 137.096 226.795 1.00 126.51 ? 236 ARG E N   1 
ATOM   9796  C CA  . ARG D 2 220 ? 146.160 136.795 225.374 1.00 125.22 ? 236 ARG E CA  1 
ATOM   9797  C C   . ARG D 2 220 ? 145.267 135.595 225.089 1.00 125.97 ? 236 ARG E C   1 
ATOM   9798  O O   . ARG D 2 220 ? 145.116 135.219 223.922 1.00 125.15 ? 236 ARG E O   1 
ATOM   9799  C CB  . ARG D 2 220 ? 147.549 136.555 224.773 1.00 122.00 ? 236 ARG E CB  1 
ATOM   9800  C CG  . ARG D 2 220 ? 148.495 137.738 224.897 1.00 119.00 ? 236 ARG E CG  1 
ATOM   9801  C CD  . ARG D 2 220 ? 149.903 137.360 224.467 1.00 117.94 ? 236 ARG E CD  1 
ATOM   9802  N NE  . ARG D 2 220 ? 150.873 138.403 224.781 1.00 117.21 ? 236 ARG E NE  1 
ATOM   9803  C CZ  . ARG D 2 220 ? 152.175 138.308 224.548 1.00 113.70 ? 236 ARG E CZ  1 
ATOM   9804  N NH1 . ARG D 2 220 ? 152.701 137.228 223.995 1.00 114.75 ? 236 ARG E NH1 1 
ATOM   9805  N NH2 . ARG D 2 220 ? 152.969 139.323 224.877 1.00 109.95 ? 236 ARG E NH2 1 
ATOM   9806  N N   . GLU D 2 221 ? 144.678 134.985 226.121 1.00 126.39 ? 237 GLU E N   1 
ATOM   9807  C CA  . GLU D 2 221 ? 143.835 133.813 225.906 1.00 127.18 ? 237 GLU E CA  1 
ATOM   9808  C C   . GLU D 2 221 ? 142.597 134.163 225.090 1.00 125.15 ? 237 GLU E C   1 
ATOM   9809  O O   . GLU D 2 221 ? 142.182 133.392 224.217 1.00 123.20 ? 237 GLU E O   1 
ATOM   9810  C CB  . GLU D 2 221 ? 143.438 133.198 227.247 1.00 126.63 ? 237 GLU E CB  1 
ATOM   9811  C CG  . GLU D 2 221 ? 142.714 131.868 227.129 1.00 126.55 ? 237 GLU E CG  1 
ATOM   9812  C CD  . GLU D 2 221 ? 143.562 130.800 226.467 1.00 126.78 ? 237 GLU E CD  1 
ATOM   9813  O OE1 . GLU D 2 221 ? 144.787 130.775 226.711 1.00 125.39 ? 237 GLU E OE1 1 
ATOM   9814  O OE2 . GLU D 2 221 ? 143.004 129.985 225.702 1.00 126.19 ? 237 GLU E OE2 1 
ATOM   9815  N N   . ALA D 2 222 ? 141.988 135.319 225.364 1.00 127.04 ? 238 ALA E N   1 
ATOM   9816  C CA  . ALA D 2 222 ? 140.808 135.738 224.618 1.00 127.68 ? 238 ALA E CA  1 
ATOM   9817  C C   . ALA D 2 222 ? 141.112 136.006 223.150 1.00 128.69 ? 238 ALA E C   1 
ATOM   9818  O O   . ALA D 2 222 ? 140.208 135.905 222.315 1.00 128.26 ? 238 ALA E O   1 
ATOM   9819  C CB  . ALA D 2 222 ? 140.196 136.985 225.257 1.00 123.96 ? 238 ALA E CB  1 
ATOM   9820  N N   . PHE D 2 223 ? 142.359 136.341 222.817 1.00 128.02 ? 239 PHE E N   1 
ATOM   9821  C CA  . PHE D 2 223 ? 142.742 136.599 221.436 1.00 124.66 ? 239 PHE E CA  1 
ATOM   9822  C C   . PHE D 2 223 ? 143.011 135.328 220.644 1.00 123.82 ? 239 PHE E C   1 
ATOM   9823  O O   . PHE D 2 223 ? 143.230 135.414 219.431 1.00 121.98 ? 239 PHE E O   1 
ATOM   9824  C CB  . PHE D 2 223 ? 143.986 137.490 221.389 1.00 120.60 ? 239 PHE E CB  1 
ATOM   9825  C CG  . PHE D 2 223 ? 143.809 138.820 222.062 1.00 120.59 ? 239 PHE E CG  1 
ATOM   9826  C CD1 . PHE D 2 223 ? 142.638 139.541 221.907 1.00 121.32 ? 239 PHE E CD1 1 
ATOM   9827  C CD2 . PHE D 2 223 ? 144.819 139.352 222.847 1.00 120.39 ? 239 PHE E CD2 1 
ATOM   9828  C CE1 . PHE D 2 223 ? 142.475 140.767 222.524 1.00 123.15 ? 239 PHE E CE1 1 
ATOM   9829  C CE2 . PHE D 2 223 ? 144.663 140.576 223.466 1.00 122.26 ? 239 PHE E CE2 1 
ATOM   9830  C CZ  . PHE D 2 223 ? 143.490 141.286 223.305 1.00 121.61 ? 239 PHE E CZ  1 
ATOM   9831  N N   . ALA D 2 224 ? 143.005 134.162 221.294 1.00 123.93 ? 240 ALA E N   1 
ATOM   9832  C CA  . ALA D 2 224 ? 143.386 132.928 220.612 1.00 123.84 ? 240 ALA E CA  1 
ATOM   9833  C C   . ALA D 2 224 ? 142.438 132.602 219.465 1.00 123.67 ? 240 ALA E C   1 
ATOM   9834  O O   . ALA D 2 224 ? 142.883 132.246 218.369 1.00 121.94 ? 240 ALA E O   1 
ATOM   9835  C CB  . ALA D 2 224 ? 143.437 131.772 221.611 1.00 121.67 ? 240 ALA E CB  1 
ATOM   9836  N N   . GLU D 2 225 ? 141.129 132.728 219.694 1.00 125.20 ? 241 GLU E N   1 
ATOM   9837  C CA  . GLU D 2 225 ? 140.157 132.349 218.671 1.00 126.29 ? 241 GLU E CA  1 
ATOM   9838  C C   . GLU D 2 225 ? 140.286 133.218 217.426 1.00 124.14 ? 241 GLU E C   1 
ATOM   9839  O O   . GLU D 2 225 ? 140.168 132.723 216.298 1.00 122.49 ? 241 GLU E O   1 
ATOM   9840  C CB  . GLU D 2 225 ? 138.740 132.434 219.240 1.00 127.00 ? 241 GLU E CB  1 
ATOM   9841  C CG  . GLU D 2 225 ? 137.695 131.694 218.420 1.00 126.97 ? 241 GLU E CG  1 
ATOM   9842  C CD  . GLU D 2 225 ? 138.187 130.348 217.926 1.00 129.18 ? 241 GLU E CD  1 
ATOM   9843  O OE1 . GLU D 2 225 ? 138.394 129.445 218.764 1.00 128.63 ? 241 GLU E OE1 1 
ATOM   9844  O OE2 . GLU D 2 225 ? 138.367 130.192 216.700 1.00 129.16 ? 241 GLU E OE2 1 
ATOM   9845  N N   . SER D 2 226 ? 140.525 134.519 217.612 1.00 123.10 ? 242 SER E N   1 
ATOM   9846  C CA  . SER D 2 226 ? 140.622 135.427 216.474 1.00 120.62 ? 242 SER E CA  1 
ATOM   9847  C C   . SER D 2 226 ? 141.788 135.057 215.566 1.00 119.41 ? 242 SER E C   1 
ATOM   9848  O O   . SER D 2 226 ? 141.668 135.117 214.336 1.00 117.72 ? 242 SER E O   1 
ATOM   9849  C CB  . SER D 2 226 ? 140.760 136.868 216.966 1.00 120.43 ? 242 SER E CB  1 
ATOM   9850  O OG  . SER D 2 226 ? 141.955 137.039 217.707 1.00 119.38 ? 242 SER E OG  1 
ATOM   9851  N N   . LEU D 2 227 ? 142.927 134.682 216.153 1.00 120.26 ? 243 LEU E N   1 
ATOM   9852  C CA  . LEU D 2 227 ? 144.077 134.286 215.345 1.00 118.30 ? 243 LEU E CA  1 
ATOM   9853  C C   . LEU D 2 227 ? 143.777 133.036 214.527 1.00 116.96 ? 243 LEU E C   1 
ATOM   9854  O O   . LEU D 2 227 ? 144.140 132.960 213.348 1.00 114.03 ? 243 LEU E O   1 
ATOM   9855  C CB  . LEU D 2 227 ? 145.298 134.067 216.238 1.00 115.78 ? 243 LEU E CB  1 
ATOM   9856  C CG  . LEU D 2 227 ? 145.612 135.190 217.228 1.00 111.79 ? 243 LEU E CG  1 
ATOM   9857  C CD1 . LEU D 2 227 ? 146.633 134.730 218.252 1.00 109.66 ? 243 LEU E CD1 1 
ATOM   9858  C CD2 . LEU D 2 227 ? 146.103 136.428 216.496 1.00 104.83 ? 243 LEU E CD2 1 
ATOM   9859  N N   . ARG D 2 228 ? 143.117 132.045 215.133 1.00 118.30 ? 244 ARG E N   1 
ATOM   9860  C CA  . ARG D 2 228 ? 142.767 130.836 214.393 1.00 118.51 ? 244 ARG E CA  1 
ATOM   9861  C C   . ARG D 2 228 ? 141.788 131.142 213.266 1.00 118.46 ? 244 ARG E C   1 
ATOM   9862  O O   . ARG D 2 228 ? 141.920 130.607 212.159 1.00 116.39 ? 244 ARG E O   1 
ATOM   9863  C CB  . ARG D 2 228 ? 142.180 129.785 215.336 1.00 119.62 ? 244 ARG E CB  1 
ATOM   9864  C CG  . ARG D 2 228 ? 142.884 129.675 216.675 1.00 121.20 ? 244 ARG E CG  1 
ATOM   9865  C CD  . ARG D 2 228 ? 143.932 128.576 216.675 1.00 121.66 ? 244 ARG E CD  1 
ATOM   9866  N NE  . ARG D 2 228 ? 144.717 128.581 217.904 1.00 120.45 ? 244 ARG E NE  1 
ATOM   9867  C CZ  . ARG D 2 228 ? 144.563 127.715 218.896 1.00 117.77 ? 244 ARG E CZ  1 
ATOM   9868  N NH1 . ARG D 2 228 ? 143.652 126.757 218.842 1.00 116.88 ? 244 ARG E NH1 1 
ATOM   9869  N NH2 . ARG D 2 228 ? 145.340 127.814 219.971 1.00 113.00 ? 244 ARG E NH2 1 
ATOM   9870  N N   . THR D 2 229 ? 140.795 131.995 213.529 1.00 120.31 ? 245 THR E N   1 
ATOM   9871  C CA  . THR D 2 229 ? 139.827 132.333 212.490 1.00 118.57 ? 245 THR E CA  1 
ATOM   9872  C C   . THR D 2 229 ? 140.464 133.122 211.353 1.00 115.68 ? 245 THR E C   1 
ATOM   9873  O O   . THR D 2 229 ? 140.105 132.923 210.187 1.00 115.86 ? 245 THR E O   1 
ATOM   9874  C CB  . THR D 2 229 ? 138.659 133.122 213.083 1.00 120.22 ? 245 THR E CB  1 
ATOM   9875  O OG1 . THR D 2 229 ? 139.151 134.308 213.718 1.00 120.76 ? 245 THR E OG1 1 
ATOM   9876  C CG2 . THR D 2 229 ? 137.901 132.277 214.097 1.00 119.33 ? 245 THR E CG2 1 
ATOM   9877  N N   . SER D 2 230 ? 141.402 134.013 211.664 1.00 115.03 ? 246 SER E N   1 
ATOM   9878  C CA  . SER D 2 230 ? 142.022 134.873 210.665 1.00 113.04 ? 246 SER E CA  1 
ATOM   9879  C C   . SER D 2 230 ? 143.278 134.271 210.050 1.00 111.04 ? 246 SER E C   1 
ATOM   9880  O O   . SER D 2 230 ? 143.894 134.909 209.191 1.00 107.23 ? 246 SER E O   1 
ATOM   9881  C CB  . SER D 2 230 ? 142.358 136.236 211.280 1.00 111.28 ? 246 SER E CB  1 
ATOM   9882  O OG  . SER D 2 230 ? 142.748 137.164 210.283 1.00 102.11 ? 246 SER E OG  1 
ATOM   9883  N N   . LEU D 2 231 ? 143.670 133.067 210.459 1.00 113.00 ? 247 LEU E N   1 
ATOM   9884  C CA  . LEU D 2 231 ? 144.880 132.427 209.945 1.00 110.59 ? 247 LEU E CA  1 
ATOM   9885  C C   . LEU D 2 231 ? 144.541 131.776 208.610 1.00 111.93 ? 247 LEU E C   1 
ATOM   9886  O O   . LEU D 2 231 ? 143.939 130.703 208.547 1.00 111.66 ? 247 LEU E O   1 
ATOM   9887  C CB  . LEU D 2 231 ? 145.418 131.411 210.946 1.00 109.49 ? 247 LEU E CB  1 
ATOM   9888  C CG  . LEU D 2 231 ? 146.923 131.128 210.996 1.00 104.05 ? 247 LEU E CG  1 
ATOM   9889  C CD1 . LEU D 2 231 ? 147.209 130.017 211.993 1.00 105.73 ? 247 LEU E CD1 1 
ATOM   9890  C CD2 . LEU D 2 231 ? 147.489 130.777 209.630 1.00 104.92 ? 247 LEU E CD2 1 
ATOM   9891  N N   . LYS D 2 232 ? 144.935 132.436 207.526 1.00 111.97 ? 248 LYS E N   1 
ATOM   9892  C CA  . LYS D 2 232 ? 144.764 131.910 206.179 1.00 113.92 ? 248 LYS E CA  1 
ATOM   9893  C C   . LYS D 2 232 ? 146.129 131.582 205.590 1.00 114.38 ? 248 LYS E C   1 
ATOM   9894  O O   . LYS D 2 232 ? 147.085 132.345 205.764 1.00 109.98 ? 248 LYS E O   1 
ATOM   9895  C CB  . LYS D 2 232 ? 144.020 132.908 205.290 1.00 111.10 ? 248 LYS E CB  1 
ATOM   9896  C CG  . LYS D 2 232 ? 144.571 134.322 205.337 1.00 107.27 ? 248 LYS E CG  1 
ATOM   9897  C CD  . LYS D 2 232 ? 143.482 135.349 205.070 1.00 108.00 ? 248 LYS E CD  1 
ATOM   9898  C CE  . LYS D 2 232 ? 142.273 135.118 205.963 1.00 108.92 ? 248 LYS E CE  1 
ATOM   9899  N NZ  . LYS D 2 232 ? 141.194 136.111 205.707 1.00 102.86 ? 248 LYS E NZ  1 
ATOM   9900  N N   . GLU D 2 233 ? 146.220 130.444 204.909 1.00 117.23 ? 249 GLU E N   1 
ATOM   9901  C CA  . GLU D 2 233 ? 147.459 129.988 204.300 1.00 114.86 ? 249 GLU E CA  1 
ATOM   9902  C C   . GLU D 2 233 ? 147.321 129.951 202.783 1.00 115.98 ? 249 GLU E C   1 
ATOM   9903  O O   . GLU D 2 233 ? 146.216 129.910 202.235 1.00 115.30 ? 249 GLU E O   1 
ATOM   9904  C CB  . GLU D 2 233 ? 147.852 128.604 204.828 1.00 111.94 ? 249 GLU E CB  1 
ATOM   9905  C CG  . GLU D 2 233 ? 148.426 128.621 206.235 1.00 111.73 ? 249 GLU E CG  1 
ATOM   9906  C CD  . GLU D 2 233 ? 149.066 127.302 206.620 1.00 114.29 ? 249 GLU E CD  1 
ATOM   9907  O OE1 . GLU D 2 233 ? 149.397 126.512 205.711 1.00 114.71 ? 249 GLU E OE1 1 
ATOM   9908  O OE2 . GLU D 2 233 ? 149.239 127.054 207.832 1.00 111.82 ? 249 GLU E OE2 1 
ATOM   9909  N N   . ILE D 2 234 ? 148.469 129.968 202.106 1.00 115.97 ? 250 ILE E N   1 
ATOM   9910  C CA  . ILE D 2 234 ? 148.530 129.994 200.652 1.00 117.97 ? 250 ILE E CA  1 
ATOM   9911  C C   . ILE D 2 234 ? 149.524 128.938 200.183 1.00 115.85 ? 250 ILE E C   1 
ATOM   9912  O O   . ILE D 2 234 ? 150.292 128.379 200.966 1.00 111.24 ? 250 ILE E O   1 
ATOM   9913  C CB  . ILE D 2 234 ? 148.920 131.383 200.105 1.00 116.15 ? 250 ILE E CB  1 
ATOM   9914  C CG1 . ILE D 2 234 ? 150.211 131.872 200.765 1.00 112.11 ? 250 ILE E CG1 1 
ATOM   9915  C CG2 . ILE D 2 234 ? 147.791 132.380 200.320 1.00 111.04 ? 250 ILE E CG2 1 
ATOM   9916  C CD1 . ILE D 2 234 ? 150.579 133.295 200.408 1.00 106.19 ? 250 ILE E CD1 1 
ATOM   9917  N N   . GLY D 2 235 ? 149.494 128.671 198.881 1.00 114.70 ? 251 GLY E N   1 
ATOM   9918  C CA  . GLY D 2 235 ? 150.396 127.718 198.273 1.00 114.08 ? 251 GLY E CA  1 
ATOM   9919  C C   . GLY D 2 235 ? 151.737 128.338 197.930 1.00 116.67 ? 251 GLY E C   1 
ATOM   9920  O O   . GLY D 2 235 ? 152.052 129.474 198.289 1.00 116.62 ? 251 GLY E O   1 
ATOM   9921  N N   . GLU D 2 236 ? 152.543 127.561 197.212 1.00 114.25 ? 252 GLU E N   1 
ATOM   9922  C CA  . GLU D 2 236 ? 153.887 127.978 196.833 1.00 112.46 ? 252 GLU E CA  1 
ATOM   9923  C C   . GLU D 2 236 ? 153.845 128.670 195.476 1.00 109.56 ? 252 GLU E C   1 
ATOM   9924  O O   . GLU D 2 236 ? 153.496 128.048 194.466 1.00 107.27 ? 252 GLU E O   1 
ATOM   9925  C CB  . GLU D 2 236 ? 154.833 126.778 196.798 1.00 112.71 ? 252 GLU E CB  1 
ATOM   9926  C CG  . GLU D 2 236 ? 155.428 126.417 198.149 1.00 112.30 ? 252 GLU E CG  1 
ATOM   9927  C CD  . GLU D 2 236 ? 154.382 125.950 199.141 1.00 113.08 ? 252 GLU E CD  1 
ATOM   9928  O OE1 . GLU D 2 236 ? 153.483 125.181 198.740 1.00 112.87 ? 252 GLU E OE1 1 
ATOM   9929  O OE2 . GLU D 2 236 ? 154.458 126.353 200.320 1.00 112.00 ? 252 GLU E OE2 1 
ATOM   9930  N N   . ASN D 2 237 ? 154.203 129.954 195.454 1.00 109.76 ? 253 ASN E N   1 
ATOM   9931  C CA  . ASN D 2 237 ? 154.250 130.726 194.222 1.00 108.48 ? 253 ASN E CA  1 
ATOM   9932  C C   . ASN D 2 237 ? 155.629 131.295 193.922 1.00 107.62 ? 253 ASN E C   1 
ATOM   9933  O O   . ASN D 2 237 ? 155.822 131.872 192.845 1.00 102.75 ? 253 ASN E O   1 
ATOM   9934  C CB  . ASN D 2 237 ? 153.225 131.869 194.265 1.00 108.01 ? 253 ASN E CB  1 
ATOM   9935  C CG  . ASN D 2 237 ? 152.001 131.585 193.417 1.00 107.15 ? 253 ASN E CG  1 
ATOM   9936  O OD1 . ASN D 2 237 ? 152.014 130.697 192.565 1.00 103.79 ? 253 ASN E OD1 1 
ATOM   9937  N ND2 . ASN D 2 237 ? 150.935 132.344 193.643 1.00 109.23 ? 253 ASN E ND2 1 
ATOM   9938  N N   . VAL D 2 238 ? 156.590 131.155 194.834 1.00 108.13 ? 254 VAL E N   1 
ATOM   9939  C CA  . VAL D 2 238 ? 157.967 131.576 194.582 1.00 102.72 ? 254 VAL E CA  1 
ATOM   9940  C C   . VAL D 2 238 ? 158.598 130.501 193.702 1.00 98.04  ? 254 VAL E C   1 
ATOM   9941  O O   . VAL D 2 238 ? 159.053 129.467 194.195 1.00 99.36  ? 254 VAL E O   1 
ATOM   9942  C CB  . VAL D 2 238 ? 158.751 131.783 195.880 1.00 101.13 ? 254 VAL E CB  1 
ATOM   9943  C CG1 . VAL D 2 238 ? 160.213 132.082 195.580 1.00 100.31 ? 254 VAL E CG1 1 
ATOM   9944  C CG2 . VAL D 2 238 ? 158.131 132.903 196.700 1.00 98.54  ? 254 VAL E CG2 1 
ATOM   9945  N N   . HIS D 2 239 ? 158.618 130.737 192.393 1.00 89.74  ? 255 HIS E N   1 
ATOM   9946  C CA  . HIS D 2 239 ? 159.000 129.713 191.435 1.00 86.71  ? 255 HIS E CA  1 
ATOM   9947  C C   . HIS D 2 239 ? 159.958 130.286 190.402 1.00 79.53  ? 255 HIS E C   1 
ATOM   9948  O O   . HIS D 2 239 ? 159.941 131.484 190.109 1.00 77.14  ? 255 HIS E O   1 
ATOM   9949  C CB  . HIS D 2 239 ? 157.773 129.129 190.724 1.00 86.60  ? 255 HIS E CB  1 
ATOM   9950  C CG  . HIS D 2 239 ? 157.185 127.936 191.410 1.00 90.75  ? 255 HIS E CG  1 
ATOM   9951  N ND1 . HIS D 2 239 ? 156.746 126.826 190.722 1.00 88.82  ? 255 HIS E ND1 1 
ATOM   9952  C CD2 . HIS D 2 239 ? 156.962 127.680 192.720 1.00 95.99  ? 255 HIS E CD2 1 
ATOM   9953  C CE1 . HIS D 2 239 ? 156.278 125.936 191.580 1.00 94.82  ? 255 HIS E CE1 1 
ATOM   9954  N NE2 . HIS D 2 239 ? 156.398 126.430 192.799 1.00 98.78  ? 255 HIS E NE2 1 
ATOM   9955  N N   . ILE D 2 240 ? 160.796 129.409 189.857 1.00 75.53  ? 256 ILE E N   1 
ATOM   9956  C CA  . ILE D 2 240 ? 161.650 129.711 188.715 1.00 67.21  ? 256 ILE E CA  1 
ATOM   9957  C C   . ILE D 2 240 ? 161.375 128.633 187.678 1.00 69.63  ? 256 ILE E C   1 
ATOM   9958  O O   . ILE D 2 240 ? 161.610 127.446 187.935 1.00 76.07  ? 256 ILE E O   1 
ATOM   9959  C CB  . ILE D 2 240 ? 163.140 129.746 189.083 1.00 71.36  ? 256 ILE E CB  1 
ATOM   9960  C CG1 . ILE D 2 240 ? 163.387 130.681 190.270 1.00 68.39  ? 256 ILE E CG1 1 
ATOM   9961  C CG2 . ILE D 2 240 ? 163.975 130.171 187.884 1.00 64.92  ? 256 ILE E CG2 1 
ATOM   9962  C CD1 . ILE D 2 240 ? 163.420 132.143 189.901 1.00 64.13  ? 256 ILE E CD1 1 
ATOM   9963  N N   . TYR D 2 241 ? 160.874 129.035 186.515 1.00 65.46  ? 257 TYR E N   1 
ATOM   9964  C CA  . TYR D 2 241 ? 160.555 128.110 185.431 1.00 65.88  ? 257 TYR E CA  1 
ATOM   9965  C C   . TYR D 2 241 ? 161.638 128.232 184.367 1.00 62.32  ? 257 TYR E C   1 
ATOM   9966  O O   . TYR D 2 241 ? 161.643 129.181 183.582 1.00 64.14  ? 257 TYR E O   1 
ATOM   9967  C CB  . TYR D 2 241 ? 159.178 128.412 184.848 1.00 67.30  ? 257 TYR E CB  1 
ATOM   9968  C CG  . TYR D 2 241 ? 158.052 127.593 185.432 1.00 71.49  ? 257 TYR E CG  1 
ATOM   9969  C CD1 . TYR D 2 241 ? 157.908 126.250 185.114 1.00 72.38  ? 257 TYR E CD1 1 
ATOM   9970  C CD2 . TYR D 2 241 ? 157.125 128.165 186.291 1.00 73.09  ? 257 TYR E CD2 1 
ATOM   9971  C CE1 . TYR D 2 241 ? 156.879 125.499 185.640 1.00 75.28  ? 257 TYR E CE1 1 
ATOM   9972  C CE2 . TYR D 2 241 ? 156.092 127.421 186.823 1.00 79.06  ? 257 TYR E CE2 1 
ATOM   9973  C CZ  . TYR D 2 241 ? 155.973 126.089 186.494 1.00 80.34  ? 257 TYR E CZ  1 
ATOM   9974  O OH  . TYR D 2 241 ? 154.945 125.344 187.022 1.00 80.61  ? 257 TYR E OH  1 
ATOM   9975  N N   . LEU D 2 242 ? 162.555 127.271 184.335 1.00 63.95  ? 258 LEU E N   1 
ATOM   9976  C CA  . LEU D 2 242 ? 163.566 127.209 183.290 1.00 65.59  ? 258 LEU E CA  1 
ATOM   9977  C C   . LEU D 2 242 ? 163.334 125.977 182.429 1.00 67.23  ? 258 LEU E C   1 
ATOM   9978  O O   . LEU D 2 242 ? 163.171 124.869 182.950 1.00 71.20  ? 258 LEU E O   1 
ATOM   9979  C CB  . LEU D 2 242 ? 164.986 127.204 183.868 1.00 65.25  ? 258 LEU E CB  1 
ATOM   9980  C CG  . LEU D 2 242 ? 165.429 126.229 184.956 1.00 61.77  ? 258 LEU E CG  1 
ATOM   9981  C CD1 . LEU D 2 242 ? 166.045 124.988 184.353 1.00 67.92  ? 258 LEU E CD1 1 
ATOM   9982  C CD2 . LEU D 2 242 ? 166.443 126.922 185.836 1.00 58.81  ? 258 LEU E CD2 1 
ATOM   9983  N N   . ILE D 2 243 ? 163.302 126.180 181.114 1.00 66.14  ? 259 ILE E N   1 
ATOM   9984  C CA  . ILE D 2 243 ? 163.148 125.102 180.152 1.00 71.71  ? 259 ILE E CA  1 
ATOM   9985  C C   . ILE D 2 243 ? 164.410 125.047 179.302 1.00 74.52  ? 259 ILE E C   1 
ATOM   9986  O O   . ILE D 2 243 ? 165.138 126.033 179.161 1.00 74.05  ? 259 ILE E O   1 
ATOM   9987  C CB  . ILE D 2 243 ? 161.894 125.276 179.270 1.00 69.10  ? 259 ILE E CB  1 
ATOM   9988  C CG1 . ILE D 2 243 ? 162.217 126.074 178.010 1.00 65.69  ? 259 ILE E CG1 1 
ATOM   9989  C CG2 . ILE D 2 243 ? 160.795 125.983 180.043 1.00 67.66  ? 259 ILE E CG2 1 
ATOM   9990  C CD1 . ILE D 2 243 ? 161.027 126.276 177.106 1.00 66.34  ? 259 ILE E CD1 1 
ATOM   9991  N N   . GLY D 2 244 ? 164.674 123.874 178.744 1.00 81.75  ? 260 GLY E N   1 
ATOM   9992  C CA  . GLY D 2 244 ? 165.884 123.710 177.960 1.00 90.92  ? 260 GLY E CA  1 
ATOM   9993  C C   . GLY D 2 244 ? 165.866 122.412 177.189 1.00 101.69 ? 260 GLY E C   1 
ATOM   9994  O O   . GLY D 2 244 ? 164.975 121.573 177.353 1.00 103.22 ? 260 GLY E O   1 
ATOM   9995  N N   . LYS D 2 245 ? 166.876 122.262 176.338 1.00 109.09 ? 261 LYS E N   1 
ATOM   9996  C CA  . LYS D 2 245 ? 167.035 121.095 175.484 1.00 114.31 ? 261 LYS E CA  1 
ATOM   9997  C C   . LYS D 2 245 ? 168.279 120.328 175.906 1.00 116.56 ? 261 LYS E C   1 
ATOM   9998  O O   . LYS D 2 245 ? 169.367 120.907 176.001 1.00 114.23 ? 261 LYS E O   1 
ATOM   9999  C CB  . LYS D 2 245 ? 167.144 121.508 174.014 1.00 111.33 ? 261 LYS E CB  1 
ATOM   10000 C CG  . LYS D 2 245 ? 166.976 120.367 173.030 1.00 112.82 ? 261 LYS E CG  1 
ATOM   10001 C CD  . LYS D 2 245 ? 165.509 120.050 172.812 1.00 115.71 ? 261 LYS E CD  1 
ATOM   10002 C CE  . LYS D 2 245 ? 164.817 121.153 172.028 1.00 115.51 ? 261 LYS E CE  1 
ATOM   10003 N NZ  . LYS D 2 245 ? 163.920 120.613 170.971 1.00 113.36 ? 261 LYS E NZ  1 
ATOM   10004 N N   . GLU D 2 246 ? 168.119 119.033 176.160 1.00 121.90 ? 262 GLU E N   1 
ATOM   10005 C CA  . GLU D 2 246 ? 169.268 118.197 176.462 1.00 124.92 ? 262 GLU E CA  1 
ATOM   10006 C C   . GLU D 2 246 ? 170.090 117.951 175.198 1.00 127.93 ? 262 GLU E C   1 
ATOM   10007 O O   . GLU D 2 246 ? 169.597 118.060 174.072 1.00 127.67 ? 262 GLU E O   1 
ATOM   10008 C CB  . GLU D 2 246 ? 168.825 116.869 177.076 1.00 125.05 ? 262 GLU E CB  1 
ATOM   10009 C CG  . GLU D 2 246 ? 169.836 116.270 178.041 1.00 124.94 ? 262 GLU E CG  1 
ATOM   10010 C CD  . GLU D 2 246 ? 169.290 115.071 178.792 1.00 127.43 ? 262 GLU E CD  1 
ATOM   10011 O OE1 . GLU D 2 246 ? 168.076 114.802 178.683 1.00 128.79 ? 262 GLU E OE1 1 
ATOM   10012 O OE2 . GLU D 2 246 ? 170.077 114.396 179.489 1.00 127.47 ? 262 GLU E OE2 1 
ATOM   10013 N N   . SER D 2 247 ? 171.369 117.626 175.401 1.00 127.71 ? 263 SER E N   1 
ATOM   10014 C CA  . SER D 2 247 ? 172.266 117.420 174.268 1.00 128.95 ? 263 SER E CA  1 
ATOM   10015 C C   . SER D 2 247 ? 171.827 116.237 173.414 1.00 129.51 ? 263 SER E C   1 
ATOM   10016 O O   . SER D 2 247 ? 171.846 116.313 172.179 1.00 127.46 ? 263 SER E O   1 
ATOM   10017 C CB  . SER D 2 247 ? 173.698 117.221 174.765 1.00 127.85 ? 263 SER E CB  1 
ATOM   10018 O OG  . SER D 2 247 ? 173.746 116.274 175.817 1.00 125.40 ? 263 SER E OG  1 
ATOM   10019 N N   . SER D 2 248 ? 171.426 115.138 174.049 1.00 129.81 ? 264 SER E N   1 
ATOM   10020 C CA  . SER D 2 248 ? 171.067 113.916 173.343 1.00 130.68 ? 264 SER E CA  1 
ATOM   10021 C C   . SER D 2 248 ? 169.568 113.762 173.122 1.00 131.60 ? 264 SER E C   1 
ATOM   10022 O O   . SER D 2 248 ? 169.141 112.749 172.559 1.00 130.86 ? 264 SER E O   1 
ATOM   10023 C CB  . SER D 2 248 ? 171.600 112.695 174.101 1.00 128.50 ? 264 SER E CB  1 
ATOM   10024 O OG  . SER D 2 248 ? 170.852 112.464 175.282 1.00 130.51 ? 264 SER E OG  1 
ATOM   10025 N N   . ARG D 2 249 ? 168.760 114.733 173.542 1.00 129.40 ? 265 ARG E N   1 
ATOM   10026 C CA  . ARG D 2 249 ? 167.312 114.650 173.412 1.00 128.10 ? 265 ARG E CA  1 
ATOM   10027 C C   . ARG D 2 249 ? 166.789 115.885 172.695 1.00 125.34 ? 265 ARG E C   1 
ATOM   10028 O O   . ARG D 2 249 ? 167.247 117.002 172.950 1.00 124.90 ? 265 ARG E O   1 
ATOM   10029 C CB  . ARG D 2 249 ? 166.639 114.506 174.783 1.00 126.87 ? 265 ARG E CB  1 
ATOM   10030 C CG  . ARG D 2 249 ? 165.132 114.314 174.724 1.00 125.10 ? 265 ARG E CG  1 
ATOM   10031 C CD  . ARG D 2 249 ? 164.483 114.682 176.048 1.00 125.10 ? 265 ARG E CD  1 
ATOM   10032 N NE  . ARG D 2 249 ? 165.111 115.846 176.659 1.00 125.08 ? 265 ARG E NE  1 
ATOM   10033 C CZ  . ARG D 2 249 ? 165.138 116.084 177.963 1.00 121.51 ? 265 ARG E CZ  1 
ATOM   10034 N NH1 . ARG D 2 249 ? 164.583 115.252 178.829 1.00 118.59 ? 265 ARG E NH1 1 
ATOM   10035 N NH2 . ARG D 2 249 ? 165.738 117.184 178.410 1.00 119.99 ? 265 ARG E NH2 1 
ATOM   10036 N N   . THR D 2 250 ? 165.828 115.676 171.798 1.00 123.86 ? 266 THR E N   1 
ATOM   10037 C CA  . THR D 2 250 ? 165.247 116.747 171.002 1.00 124.69 ? 266 THR E CA  1 
ATOM   10038 C C   . THR D 2 250 ? 163.945 117.278 171.587 1.00 124.74 ? 266 THR E C   1 
ATOM   10039 O O   . THR D 2 250 ? 163.259 118.067 170.930 1.00 123.60 ? 266 THR E O   1 
ATOM   10040 C CB  . THR D 2 250 ? 165.014 116.272 169.566 1.00 126.07 ? 266 THR E CB  1 
ATOM   10041 O OG1 . THR D 2 250 ? 164.431 114.962 169.583 1.00 129.78 ? 266 THR E OG1 1 
ATOM   10042 C CG2 . THR D 2 250 ? 166.329 116.226 168.803 1.00 122.39 ? 266 THR E CG2 1 
ATOM   10043 N N   . HIS D 2 251 ? 163.589 116.867 172.801 1.00 124.18 ? 267 HIS E N   1 
ATOM   10044 C CA  . HIS D 2 251 ? 162.369 117.319 173.456 1.00 120.92 ? 267 HIS E CA  1 
ATOM   10045 C C   . HIS D 2 251 ? 162.714 118.317 174.553 1.00 118.97 ? 267 HIS E C   1 
ATOM   10046 O O   . HIS D 2 251 ? 163.547 118.032 175.420 1.00 117.73 ? 267 HIS E O   1 
ATOM   10047 C CB  . HIS D 2 251 ? 161.595 116.138 174.041 1.00 121.84 ? 267 HIS E CB  1 
ATOM   10048 C CG  . HIS D 2 251 ? 161.253 115.082 173.037 1.00 127.51 ? 267 HIS E CG  1 
ATOM   10049 N ND1 . HIS D 2 251 ? 161.791 113.814 173.077 1.00 129.72 ? 267 HIS E ND1 1 
ATOM   10050 C CD2 . HIS D 2 251 ? 160.428 115.107 171.964 1.00 126.10 ? 267 HIS E CD2 1 
ATOM   10051 C CE1 . HIS D 2 251 ? 161.311 113.102 172.073 1.00 128.80 ? 267 HIS E CE1 1 
ATOM   10052 N NE2 . HIS D 2 251 ? 160.481 113.863 171.382 1.00 129.07 ? 267 HIS E NE2 1 
ATOM   10053 N N   . SER D 2 252 ? 162.074 119.483 174.510 1.00 116.83 ? 268 SER E N   1 
ATOM   10054 C CA  . SER D 2 252 ? 162.283 120.493 175.538 1.00 109.64 ? 268 SER E CA  1 
ATOM   10055 C C   . SER D 2 252 ? 161.636 120.053 176.845 1.00 105.87 ? 268 SER E C   1 
ATOM   10056 O O   . SER D 2 252 ? 160.489 119.595 176.860 1.00 107.09 ? 268 SER E O   1 
ATOM   10057 C CB  . SER D 2 252 ? 161.710 121.835 175.088 1.00 107.62 ? 268 SER E CB  1 
ATOM   10058 O OG  . SER D 2 252 ? 162.356 122.298 173.916 1.00 109.15 ? 268 SER E OG  1 
ATOM   10059 N N   . LEU D 2 253 ? 162.372 120.193 177.945 1.00 102.28 ? 269 LEU E N   1 
ATOM   10060 C CA  . LEU D 2 253 ? 161.902 119.799 179.267 1.00 98.51  ? 269 LEU E CA  1 
ATOM   10061 C C   . LEU D 2 253 ? 161.802 121.041 180.141 1.00 92.34  ? 269 LEU E C   1 
ATOM   10062 O O   . LEU D 2 253 ? 162.782 121.779 180.288 1.00 91.42  ? 269 LEU E O   1 
ATOM   10063 C CB  . LEU D 2 253 ? 162.839 118.765 179.893 1.00 101.45 ? 269 LEU E CB  1 
ATOM   10064 C CG  . LEU D 2 253 ? 162.631 118.431 181.371 1.00 98.78  ? 269 LEU E CG  1 
ATOM   10065 C CD1 . LEU D 2 253 ? 161.755 117.198 181.515 1.00 98.17  ? 269 LEU E CD1 1 
ATOM   10066 C CD2 . LEU D 2 253 ? 163.965 118.220 182.063 1.00 100.74 ? 269 LEU E CD2 1 
ATOM   10067 N N   . ALA D 2 254 ? 160.626 121.266 180.721 1.00 88.32  ? 270 ALA E N   1 
ATOM   10068 C CA  . ALA D 2 254 ? 160.371 122.425 181.567 1.00 82.49  ? 270 ALA E CA  1 
ATOM   10069 C C   . ALA D 2 254 ? 160.496 122.016 183.029 1.00 84.60  ? 270 ALA E C   1 
ATOM   10070 O O   . ALA D 2 254 ? 159.751 121.151 183.502 1.00 89.27  ? 270 ALA E O   1 
ATOM   10071 C CB  . ALA D 2 254 ? 158.987 123.009 181.288 1.00 76.69  ? 270 ALA E CB  1 
ATOM   10072 N N   . VAL D 2 255 ? 161.424 122.646 183.742 1.00 82.09  ? 271 VAL E N   1 
ATOM   10073 C CA  . VAL D 2 255 ? 161.719 122.326 185.134 1.00 83.29  ? 271 VAL E CA  1 
ATOM   10074 C C   . VAL D 2 255 ? 161.188 123.448 186.013 1.00 83.72  ? 271 VAL E C   1 
ATOM   10075 O O   . VAL D 2 255 ? 161.468 124.627 185.764 1.00 79.27  ? 271 VAL E O   1 
ATOM   10076 C CB  . VAL D 2 255 ? 163.228 122.124 185.357 1.00 80.03  ? 271 VAL E CB  1 
ATOM   10077 C CG1 . VAL D 2 255 ? 163.509 121.766 186.806 1.00 82.30  ? 271 VAL E CG1 1 
ATOM   10078 C CG2 . VAL D 2 255 ? 163.763 121.052 184.424 1.00 81.92  ? 271 VAL E CG2 1 
ATOM   10079 N N   . SER D 2 256 ? 160.424 123.083 187.039 1.00 87.12  ? 272 SER E N   1 
ATOM   10080 C CA  . SER D 2 256 ? 159.898 124.034 188.009 1.00 86.21  ? 272 SER E CA  1 
ATOM   10081 C C   . SER D 2 256 ? 160.703 123.938 189.297 1.00 91.07  ? 272 SER E C   1 
ATOM   10082 O O   . SER D 2 256 ? 160.949 122.836 189.799 1.00 93.38  ? 272 SER E O   1 
ATOM   10083 C CB  . SER D 2 256 ? 158.419 123.767 188.288 1.00 84.84  ? 272 SER E CB  1 
ATOM   10084 O OG  . SER D 2 256 ? 158.090 124.098 189.625 1.00 89.27  ? 272 SER E OG  1 
ATOM   10085 N N   . LEU D 2 257 ? 161.109 125.087 189.829 1.00 88.19  ? 273 LEU E N   1 
ATOM   10086 C CA  . LEU D 2 257 ? 161.939 125.147 191.023 1.00 88.54  ? 273 LEU E CA  1 
ATOM   10087 C C   . LEU D 2 257 ? 161.227 125.916 192.124 1.00 91.57  ? 273 LEU E C   1 
ATOM   10088 O O   . LEU D 2 257 ? 160.521 126.893 191.858 1.00 90.31  ? 273 LEU E O   1 
ATOM   10089 C CB  . LEU D 2 257 ? 163.283 125.816 190.739 1.00 85.94  ? 273 LEU E CB  1 
ATOM   10090 C CG  . LEU D 2 257 ? 164.120 125.276 189.586 1.00 83.02  ? 273 LEU E CG  1 
ATOM   10091 C CD1 . LEU D 2 257 ? 164.768 126.434 188.872 1.00 75.97  ? 273 LEU E CD1 1 
ATOM   10092 C CD2 . LEU D 2 257 ? 165.166 124.306 190.094 1.00 91.21  ? 273 LEU E CD2 1 
ATOM   10093 N N   . HIS D 2 258 ? 161.420 125.468 193.361 1.00 97.31  ? 274 HIS E N   1 
ATOM   10094 C CA  . HIS D 2 258 ? 160.964 126.182 194.543 1.00 102.85 ? 274 HIS E CA  1 
ATOM   10095 C C   . HIS D 2 258 ? 162.172 126.464 195.422 1.00 105.25 ? 274 HIS E C   1 
ATOM   10096 O O   . HIS D 2 258 ? 162.900 125.539 195.796 1.00 104.42 ? 274 HIS E O   1 
ATOM   10097 C CB  . HIS D 2 258 ? 159.901 125.375 195.302 1.00 104.33 ? 274 HIS E CB  1 
ATOM   10098 C CG  . HIS D 2 258 ? 159.878 125.624 196.780 1.00 109.25 ? 274 HIS E CG  1 
ATOM   10099 N ND1 . HIS D 2 258 ? 160.842 125.139 197.638 1.00 109.90 ? 274 HIS E ND1 1 
ATOM   10100 C CD2 . HIS D 2 258 ? 159.003 126.312 197.551 1.00 110.78 ? 274 HIS E CD2 1 
ATOM   10101 C CE1 . HIS D 2 258 ? 160.562 125.516 198.872 1.00 111.57 ? 274 HIS E CE1 1 
ATOM   10102 N NE2 . HIS D 2 258 ? 159.451 126.229 198.847 1.00 112.18 ? 274 HIS E NE2 1 
ATOM   10103 N N   . CYS D 2 259 ? 162.383 127.736 195.750 1.00 106.79 ? 275 CYS E N   1 
ATOM   10104 C CA  . CYS D 2 259 ? 163.499 128.154 196.588 1.00 110.79 ? 275 CYS E CA  1 
ATOM   10105 C C   . CYS D 2 259 ? 162.942 128.789 197.852 1.00 111.25 ? 275 CYS E C   1 
ATOM   10106 O O   . CYS D 2 259 ? 162.231 129.797 197.782 1.00 107.77 ? 275 CYS E O   1 
ATOM   10107 C CB  . CYS D 2 259 ? 164.412 129.130 195.846 1.00 106.13 ? 275 CYS E CB  1 
ATOM   10108 S SG  . CYS D 2 259 ? 165.843 129.688 196.802 1.00 109.66 ? 275 CYS E SG  1 
ATOM   10109 N N   . ALA D 2 260 ? 163.267 128.202 199.000 1.00 112.34 ? 276 ALA E N   1 
ATOM   10110 C CA  . ALA D 2 260 ? 162.745 128.662 200.274 1.00 111.73 ? 276 ALA E CA  1 
ATOM   10111 C C   . ALA D 2 260 ? 163.629 129.769 200.843 1.00 111.33 ? 276 ALA E C   1 
ATOM   10112 O O   . ALA D 2 260 ? 164.634 130.171 200.252 1.00 112.96 ? 276 ALA E O   1 
ATOM   10113 C CB  . ALA D 2 260 ? 162.624 127.495 201.252 1.00 110.66 ? 276 ALA E CB  1 
ATOM   10114 N N   . GLU D 2 261 ? 163.245 130.268 202.019 1.00 109.69 ? 277 GLU E N   1 
ATOM   10115 C CA  . GLU D 2 261 ? 163.976 131.340 202.682 1.00 105.78 ? 277 GLU E CA  1 
ATOM   10116 C C   . GLU D 2 261 ? 165.312 130.887 203.254 1.00 108.99 ? 277 GLU E C   1 
ATOM   10117 O O   . GLU D 2 261 ? 166.094 131.736 203.694 1.00 108.18 ? 277 GLU E O   1 
ATOM   10118 C CB  . GLU D 2 261 ? 163.116 131.940 203.794 1.00 98.25  ? 277 GLU E CB  1 
ATOM   10119 C CG  . GLU D 2 261 ? 162.645 130.925 204.816 1.00 98.16  ? 277 GLU E CG  1 
ATOM   10120 C CD  . GLU D 2 261 ? 161.251 130.411 204.516 1.00 100.05 ? 277 GLU E CD  1 
ATOM   10121 O OE1 . GLU D 2 261 ? 160.720 130.726 203.430 1.00 97.22  ? 277 GLU E OE1 1 
ATOM   10122 O OE2 . GLU D 2 261 ? 160.690 129.684 205.361 1.00 100.30 ? 277 GLU E OE2 1 
ATOM   10123 N N   . ASP D 2 262 ? 165.595 129.585 203.259 1.00 112.84 ? 278 ASP E N   1 
ATOM   10124 C CA  . ASP D 2 262 ? 166.831 129.054 203.815 1.00 114.72 ? 278 ASP E CA  1 
ATOM   10125 C C   . ASP D 2 262 ? 167.995 129.113 202.830 1.00 113.81 ? 278 ASP E C   1 
ATOM   10126 O O   . ASP D 2 262 ? 168.970 128.371 202.995 1.00 112.72 ? 278 ASP E O   1 
ATOM   10127 C CB  . ASP D 2 262 ? 166.619 127.616 204.296 1.00 118.02 ? 278 ASP E CB  1 
ATOM   10128 C CG  . ASP D 2 262 ? 166.214 126.678 203.175 1.00 120.08 ? 278 ASP E CG  1 
ATOM   10129 O OD1 . ASP D 2 262 ? 165.822 127.169 202.095 1.00 118.00 ? 278 ASP E OD1 1 
ATOM   10130 O OD2 . ASP D 2 262 ? 166.289 125.447 203.374 1.00 123.99 ? 278 ASP E OD2 1 
ATOM   10131 N N   . ASP D 2 263 ? 167.904 129.969 201.810 1.00 114.33 ? 279 ASP E N   1 
ATOM   10132 C CA  . ASP D 2 263 ? 168.973 130.175 200.831 1.00 113.62 ? 279 ASP E CA  1 
ATOM   10133 C C   . ASP D 2 263 ? 169.311 128.893 200.073 1.00 114.28 ? 279 ASP E C   1 
ATOM   10134 O O   . ASP D 2 263 ? 170.458 128.682 199.671 1.00 111.47 ? 279 ASP E O   1 
ATOM   10135 C CB  . ASP D 2 263 ? 170.229 130.751 201.494 1.00 111.92 ? 279 ASP E CB  1 
ATOM   10136 C CG  . ASP D 2 263 ? 170.357 132.247 201.296 1.00 111.31 ? 279 ASP E CG  1 
ATOM   10137 O OD1 . ASP D 2 263 ? 169.561 132.816 200.520 1.00 110.09 ? 279 ASP E OD1 1 
ATOM   10138 O OD2 . ASP D 2 263 ? 171.253 132.856 201.918 1.00 110.36 ? 279 ASP E OD2 1 
ATOM   10139 N N   . SER D 2 264 ? 168.319 128.030 199.871 1.00 117.15 ? 280 SER E N   1 
ATOM   10140 C CA  . SER D 2 264 ? 168.503 126.781 199.144 1.00 116.16 ? 280 SER E CA  1 
ATOM   10141 C C   . SER D 2 264 ? 167.454 126.683 198.048 1.00 113.57 ? 280 SER E C   1 
ATOM   10142 O O   . SER D 2 264 ? 166.273 126.951 198.289 1.00 111.65 ? 280 SER E O   1 
ATOM   10143 C CB  . SER D 2 264 ? 168.404 125.571 200.080 1.00 113.99 ? 280 SER E CB  1 
ATOM   10144 O OG  . SER D 2 264 ? 167.069 125.365 200.506 1.00 114.68 ? 280 SER E OG  1 
ATOM   10145 N N   . ILE D 2 265 ? 167.886 126.289 196.854 1.00 109.32 ? 281 ILE E N   1 
ATOM   10146 C CA  . ILE D 2 265 ? 167.008 126.123 195.703 1.00 104.80 ? 281 ILE E CA  1 
ATOM   10147 C C   . ILE D 2 265 ? 167.017 124.654 195.301 1.00 107.52 ? 281 ILE E C   1 
ATOM   10148 O O   . ILE D 2 265 ? 168.063 123.996 195.339 1.00 110.25 ? 281 ILE E O   1 
ATOM   10149 C CB  . ILE D 2 265 ? 167.434 127.034 194.529 1.00 98.86  ? 281 ILE E CB  1 
ATOM   10150 C CG1 . ILE D 2 265 ? 166.407 126.979 193.397 1.00 96.13  ? 281 ILE E CG1 1 
ATOM   10151 C CG2 . ILE D 2 265 ? 168.830 126.677 194.032 1.00 99.16  ? 281 ILE E CG2 1 
ATOM   10152 C CD1 . ILE D 2 265 ? 166.799 127.789 192.183 1.00 85.44  ? 281 ILE E CD1 1 
ATOM   10153 N N   . SER D 2 266 ? 165.844 124.132 194.949 1.00 103.12 ? 282 SER E N   1 
ATOM   10154 C CA  . SER D 2 266 ? 165.713 122.720 194.624 1.00 100.43 ? 282 SER E CA  1 
ATOM   10155 C C   . SER D 2 266 ? 164.625 122.541 193.576 1.00 99.75  ? 282 SER E C   1 
ATOM   10156 O O   . SER D 2 266 ? 163.791 123.424 193.359 1.00 100.02 ? 282 SER E O   1 
ATOM   10157 C CB  . SER D 2 266 ? 165.401 121.883 195.870 1.00 102.31 ? 282 SER E CB  1 
ATOM   10158 O OG  . SER D 2 266 ? 164.096 122.153 196.352 1.00 105.99 ? 282 SER E OG  1 
ATOM   10159 N N   . VAL D 2 267 ? 164.644 121.379 192.929 1.00 100.26 ? 283 VAL E N   1 
ATOM   10160 C CA  . VAL D 2 267 ? 163.693 121.073 191.866 1.00 100.74 ? 283 VAL E CA  1 
ATOM   10161 C C   . VAL D 2 267 ? 162.356 120.683 192.479 1.00 99.57  ? 283 VAL E C   1 
ATOM   10162 O O   . VAL D 2 267 ? 162.293 119.841 193.383 1.00 99.55  ? 283 VAL E O   1 
ATOM   10163 C CB  . VAL D 2 267 ? 164.230 119.954 190.960 1.00 99.63  ? 283 VAL E CB  1 
ATOM   10164 C CG1 . VAL D 2 267 ? 163.211 119.607 189.888 1.00 99.92  ? 283 VAL E CG1 1 
ATOM   10165 C CG2 . VAL D 2 267 ? 165.545 120.368 190.329 1.00 101.21 ? 283 VAL E CG2 1 
ATOM   10166 N N   . SER D 2 268 ? 161.280 121.299 191.988 1.00 96.94  ? 284 SER E N   1 
ATOM   10167 C CA  . SER D 2 268 ? 159.931 120.970 192.427 1.00 96.37  ? 284 SER E CA  1 
ATOM   10168 C C   . SER D 2 268 ? 159.197 120.041 191.471 1.00 100.19 ? 284 SER E C   1 
ATOM   10169 O O   . SER D 2 268 ? 158.182 119.454 191.862 1.00 102.37 ? 284 SER E O   1 
ATOM   10170 C CB  . SER D 2 268 ? 159.107 122.249 192.613 1.00 95.76  ? 284 SER E CB  1 
ATOM   10171 O OG  . SER D 2 268 ? 157.719 121.966 192.605 1.00 97.09  ? 284 SER E OG  1 
ATOM   10172 N N   . GLY D 2 269 ? 159.674 119.898 190.241 1.00 100.58 ? 285 GLY E N   1 
ATOM   10173 C CA  . GLY D 2 269 ? 159.027 119.025 189.284 1.00 100.03 ? 285 GLY E CA  1 
ATOM   10174 C C   . GLY D 2 269 ? 159.553 119.280 187.888 1.00 99.26  ? 285 GLY E C   1 
ATOM   10175 O O   . GLY D 2 269 ? 160.223 120.282 187.621 1.00 97.01  ? 285 GLY E O   1 
ATOM   10176 N N   . GLN D 2 270 ? 159.235 118.342 186.998 1.00 98.78  ? 286 GLN E N   1 
ATOM   10177 C CA  . GLN D 2 270 ? 159.665 118.434 185.609 1.00 96.07  ? 286 GLN E CA  1 
ATOM   10178 C C   . GLN D 2 270 ? 158.488 118.117 184.701 1.00 97.68  ? 286 GLN E C   1 
ATOM   10179 O O   . GLN D 2 270 ? 157.572 117.384 185.081 1.00 99.09  ? 286 GLN E O   1 
ATOM   10180 C CB  . GLN D 2 270 ? 160.832 117.486 185.305 1.00 94.72  ? 286 GLN E CB  1 
ATOM   10181 C CG  . GLN D 2 270 ? 161.753 117.207 186.481 1.00 99.00  ? 286 GLN E CG  1 
ATOM   10182 C CD  . GLN D 2 270 ? 162.838 116.206 186.141 1.00 104.84 ? 286 GLN E CD  1 
ATOM   10183 O OE1 . GLN D 2 270 ? 162.787 115.544 185.105 1.00 105.82 ? 286 GLN E OE1 1 
ATOM   10184 N NE2 . GLN D 2 270 ? 163.830 116.090 187.017 1.00 104.40 ? 286 GLN E NE2 1 
ATOM   10185 N N   . ASN D 2 271 ? 158.526 118.682 183.496 1.00 97.38  ? 287 ASN E N   1 
ATOM   10186 C CA  . ASN D 2 271 ? 157.512 118.440 182.482 1.00 97.58  ? 287 ASN E CA  1 
ATOM   10187 C C   . ASN D 2 271 ? 158.197 118.402 181.124 1.00 99.24  ? 287 ASN E C   1 
ATOM   10188 O O   . ASN D 2 271 ? 159.197 119.088 180.900 1.00 98.26  ? 287 ASN E O   1 
ATOM   10189 C CB  . ASN D 2 271 ? 156.413 119.518 182.528 1.00 97.14  ? 287 ASN E CB  1 
ATOM   10190 C CG  . ASN D 2 271 ? 155.350 119.334 181.455 1.00 104.25 ? 287 ASN E CG  1 
ATOM   10191 O OD1 . ASN D 2 271 ? 155.646 119.243 180.265 1.00 103.72 ? 287 ASN E OD1 1 
ATOM   10192 N ND2 . ASN D 2 271 ? 154.094 119.283 181.883 1.00 111.15 ? 287 ASN E ND2 1 
ATOM   10193 N N   . SER D 2 272 ? 157.647 117.600 180.217 1.00 102.04 ? 288 SER E N   1 
ATOM   10194 C CA  . SER D 2 272 ? 158.240 117.367 178.907 1.00 102.54 ? 288 SER E CA  1 
ATOM   10195 C C   . SER D 2 272 ? 157.316 117.896 177.822 1.00 102.24 ? 288 SER E C   1 
ATOM   10196 O O   . SER D 2 272 ? 156.113 117.615 177.833 1.00 103.40 ? 288 SER E O   1 
ATOM   10197 C CB  . SER D 2 272 ? 158.514 115.877 178.687 1.00 101.49 ? 288 SER E CB  1 
ATOM   10198 O OG  . SER D 2 272 ? 157.305 115.147 178.582 1.00 99.80  ? 288 SER E OG  1 
ATOM   10199 N N   . LEU D 2 273 ? 157.880 118.659 176.889 1.00 104.66 ? 289 LEU E N   1 
ATOM   10200 C CA  . LEU D 2 273 ? 157.140 119.208 175.763 1.00 109.23 ? 289 LEU E CA  1 
ATOM   10201 C C   . LEU D 2 273 ? 157.879 118.885 174.472 1.00 112.59 ? 289 LEU E C   1 
ATOM   10202 O O   . LEU D 2 273 ? 159.107 118.994 174.407 1.00 113.82 ? 289 LEU E O   1 
ATOM   10203 C CB  . LEU D 2 273 ? 156.953 120.722 175.906 1.00 111.88 ? 289 LEU E CB  1 
ATOM   10204 C CG  . LEU D 2 273 ? 156.205 121.431 174.778 1.00 111.52 ? 289 LEU E CG  1 
ATOM   10205 C CD1 . LEU D 2 273 ? 154.766 120.956 174.719 1.00 111.73 ? 289 LEU E CD1 1 
ATOM   10206 C CD2 . LEU D 2 273 ? 156.261 122.934 174.975 1.00 104.38 ? 289 LEU E CD2 1 
ATOM   10207 N N   . CYS D 2 274 ? 157.125 118.489 173.447 1.00 111.92 ? 290 CYS E N   1 
ATOM   10208 C CA  . CYS D 2 274 ? 157.693 118.028 172.187 1.00 115.72 ? 290 CYS E CA  1 
ATOM   10209 C C   . CYS D 2 274 ? 157.561 119.057 171.068 1.00 113.48 ? 290 CYS E C   1 
ATOM   10210 O O   . CYS D 2 274 ? 157.671 118.699 169.891 1.00 115.21 ? 290 CYS E O   1 
ATOM   10211 C CB  . CYS D 2 274 ? 157.039 116.711 171.768 1.00 120.59 ? 290 CYS E CB  1 
ATOM   10212 S SG  . CYS D 2 274 ? 157.117 115.406 173.018 1.00 121.31 ? 290 CYS E SG  1 
ATOM   10213 N N   . HIS D 2 275 ? 157.333 120.322 171.407 1.00 110.75 ? 291 HIS E N   1 
ATOM   10214 C CA  . HIS D 2 275 ? 157.139 121.374 170.419 1.00 110.18 ? 291 HIS E CA  1 
ATOM   10215 C C   . HIS D 2 275 ? 158.262 122.396 170.516 1.00 105.62 ? 291 HIS E C   1 
ATOM   10216 O O   . HIS D 2 275 ? 158.676 122.775 171.616 1.00 103.23 ? 291 HIS E O   1 
ATOM   10217 C CB  . HIS D 2 275 ? 155.786 122.070 170.609 1.00 108.72 ? 291 HIS E CB  1 
ATOM   10218 C CG  . HIS D 2 275 ? 154.608 121.177 170.371 1.00 113.30 ? 291 HIS E CG  1 
ATOM   10219 N ND1 . HIS D 2 275 ? 154.407 120.007 171.070 1.00 114.87 ? 291 HIS E ND1 1 
ATOM   10220 C CD2 . HIS D 2 275 ? 153.568 121.284 169.511 1.00 111.08 ? 291 HIS E CD2 1 
ATOM   10221 C CE1 . HIS D 2 275 ? 153.295 119.430 170.650 1.00 113.66 ? 291 HIS E CE1 1 
ATOM   10222 N NE2 . HIS D 2 275 ? 152.766 120.186 169.705 1.00 111.66 ? 291 HIS E NE2 1 
ATOM   10223 N N   . GLN D 2 276 ? 158.761 122.826 169.360 1.00 104.95 ? 292 GLN E N   1 
ATOM   10224 C CA  . GLN D 2 276 ? 159.735 123.907 169.324 1.00 99.62  ? 292 GLN E CA  1 
ATOM   10225 C C   . GLN D 2 276 ? 159.092 125.199 169.813 1.00 95.32  ? 292 GLN E C   1 
ATOM   10226 O O   . GLN D 2 276 ? 157.971 125.542 169.426 1.00 98.85  ? 292 GLN E O   1 
ATOM   10227 C CB  . GLN D 2 276 ? 160.298 124.082 167.911 1.00 100.56 ? 292 GLN E CB  1 
ATOM   10228 C CG  . GLN D 2 276 ? 159.277 124.455 166.841 1.00 104.41 ? 292 GLN E CG  1 
ATOM   10229 C CD  . GLN D 2 276 ? 158.387 123.293 166.444 1.00 108.59 ? 292 GLN E CD  1 
ATOM   10230 O OE1 . GLN D 2 276 ? 158.776 122.131 166.559 1.00 111.76 ? 292 GLN E OE1 1 
ATOM   10231 N NE2 . GLN D 2 276 ? 157.180 123.602 165.984 1.00 106.30 ? 292 GLN E NE2 1 
ATOM   10232 N N   . ILE D 2 277 ? 159.805 125.914 170.679 1.00 88.93  ? 293 ILE E N   1 
ATOM   10233 C CA  . ILE D 2 277 ? 159.252 127.046 171.413 1.00 84.78  ? 293 ILE E CA  1 
ATOM   10234 C C   . ILE D 2 277 ? 159.996 128.308 171.006 1.00 79.22  ? 293 ILE E C   1 
ATOM   10235 O O   . ILE D 2 277 ? 161.231 128.348 171.049 1.00 81.27  ? 293 ILE E O   1 
ATOM   10236 C CB  . ILE D 2 277 ? 159.339 126.824 172.935 1.00 82.78  ? 293 ILE E CB  1 
ATOM   10237 C CG1 . ILE D 2 277 ? 158.487 125.623 173.352 1.00 87.30  ? 293 ILE E CG1 1 
ATOM   10238 C CG2 . ILE D 2 277 ? 158.906 128.069 173.683 1.00 73.41  ? 293 ILE E CG2 1 
ATOM   10239 C CD1 . ILE D 2 277 ? 157.186 125.489 172.582 1.00 92.04  ? 293 ILE E CD1 1 
ATOM   10240 N N   . THR D 2 278 ? 159.243 129.335 170.613 1.00 73.51  ? 294 THR E N   1 
ATOM   10241 C CA  . THR D 2 278 ? 159.822 130.620 170.250 1.00 70.38  ? 294 THR E CA  1 
ATOM   10242 C C   . THR D 2 278 ? 159.666 131.679 171.333 1.00 66.05  ? 294 THR E C   1 
ATOM   10243 O O   . THR D 2 278 ? 160.403 132.670 171.316 1.00 64.53  ? 294 THR E O   1 
ATOM   10244 C CB  . THR D 2 278 ? 159.198 131.141 168.950 1.00 70.79  ? 294 THR E CB  1 
ATOM   10245 O OG1 . THR D 2 278 ? 159.586 132.505 168.746 1.00 69.87  ? 294 THR E OG1 1 
ATOM   10246 C CG2 . THR D 2 278 ? 157.681 131.052 169.012 1.00 73.30  ? 294 THR E CG2 1 
ATOM   10247 N N   . ALA D 2 279 ? 158.732 131.498 172.264 1.00 64.74  ? 295 ALA E N   1 
ATOM   10248 C CA  . ALA D 2 279 ? 158.549 132.436 173.361 1.00 58.96  ? 295 ALA E CA  1 
ATOM   10249 C C   . ALA D 2 279 ? 157.862 131.717 174.509 1.00 61.19  ? 295 ALA E C   1 
ATOM   10250 O O   . ALA D 2 279 ? 157.199 130.696 174.318 1.00 69.21  ? 295 ALA E O   1 
ATOM   10251 C CB  . ALA D 2 279 ? 157.738 133.661 172.929 1.00 55.83  ? 295 ALA E CB  1 
ATOM   10252 N N   . ALA D 2 280 ? 158.024 132.271 175.707 1.00 56.65  ? 296 ALA E N   1 
ATOM   10253 C CA  . ALA D 2 280 ? 157.403 131.711 176.898 1.00 55.64  ? 296 ALA E CA  1 
ATOM   10254 C C   . ALA D 2 280 ? 157.305 132.802 177.951 1.00 58.94  ? 296 ALA E C   1 
ATOM   10255 O O   . ALA D 2 280 ? 157.987 133.826 177.875 1.00 61.33  ? 296 ALA E O   1 
ATOM   10256 C CB  . ALA D 2 280 ? 158.185 130.509 177.434 1.00 56.49  ? 296 ALA E CB  1 
ATOM   10257 N N   . CYS D 2 281 ? 156.446 132.567 178.938 1.00 61.14  ? 297 CYS E N   1 
ATOM   10258 C CA  . CYS D 2 281 ? 156.222 133.543 179.993 1.00 55.84  ? 297 CYS E CA  1 
ATOM   10259 C C   . CYS D 2 281 ? 155.717 132.823 181.233 1.00 57.51  ? 297 CYS E C   1 
ATOM   10260 O O   . CYS D 2 281 ? 155.164 131.724 181.153 1.00 61.40  ? 297 CYS E O   1 
ATOM   10261 C CB  . CYS D 2 281 ? 155.228 134.620 179.554 1.00 54.46  ? 297 CYS E CB  1 
ATOM   10262 S SG  . CYS D 2 281 ? 154.588 135.627 180.896 1.00 68.76  ? 297 CYS E SG  1 
ATOM   10263 N N   . LYS D 2 282 ? 155.913 133.463 182.382 1.00 61.50  ? 298 LYS E N   1 
ATOM   10264 C CA  . LYS D 2 282 ? 155.443 132.948 183.663 1.00 64.23  ? 298 LYS E CA  1 
ATOM   10265 C C   . LYS D 2 282 ? 154.424 133.929 184.223 1.00 70.82  ? 298 LYS E C   1 
ATOM   10266 O O   . LYS D 2 282 ? 154.790 135.008 184.701 1.00 74.51  ? 298 LYS E O   1 
ATOM   10267 C CB  . LYS D 2 282 ? 156.600 132.742 184.638 1.00 62.63  ? 298 LYS E CB  1 
ATOM   10268 C CG  . LYS D 2 282 ? 156.158 132.487 186.067 1.00 64.52  ? 298 LYS E CG  1 
ATOM   10269 C CD  . LYS D 2 282 ? 157.271 131.881 186.895 1.00 66.00  ? 298 LYS E CD  1 
ATOM   10270 C CE  . LYS D 2 282 ? 156.913 131.880 188.368 1.00 71.27  ? 298 LYS E CE  1 
ATOM   10271 N NZ  . LYS D 2 282 ? 156.901 133.257 188.929 1.00 69.09  ? 298 LYS E NZ  1 
ATOM   10272 N N   . HIS D 2 283 ? 153.151 133.558 184.157 1.00 69.82  ? 299 HIS E N   1 
ATOM   10273 C CA  . HIS D 2 283 ? 152.064 134.354 184.706 1.00 73.25  ? 299 HIS E CA  1 
ATOM   10274 C C   . HIS D 2 283 ? 151.517 133.642 185.934 1.00 81.03  ? 299 HIS E C   1 
ATOM   10275 O O   . HIS D 2 283 ? 151.115 132.478 185.851 1.00 82.50  ? 299 HIS E O   1 
ATOM   10276 C CB  . HIS D 2 283 ? 150.959 134.561 183.668 1.00 70.76  ? 299 HIS E CB  1 
ATOM   10277 C CG  . HIS D 2 283 ? 149.948 135.596 184.052 1.00 74.64  ? 299 HIS E CG  1 
ATOM   10278 N ND1 . HIS D 2 283 ? 149.203 136.286 183.121 1.00 76.93  ? 299 HIS E ND1 1 
ATOM   10279 C CD2 . HIS D 2 283 ? 149.553 136.055 185.263 1.00 75.56  ? 299 HIS E CD2 1 
ATOM   10280 C CE1 . HIS D 2 283 ? 148.396 137.128 183.741 1.00 77.32  ? 299 HIS E CE1 1 
ATOM   10281 N NE2 . HIS D 2 283 ? 148.589 137.007 185.042 1.00 79.13  ? 299 HIS E NE2 1 
ATOM   10282 N N   . GLY D 2 284 ? 151.500 134.341 187.064 1.00 82.30  ? 300 GLY E N   1 
ATOM   10283 C CA  . GLY D 2 284 ? 151.046 133.715 188.294 1.00 79.68  ? 300 GLY E CA  1 
ATOM   10284 C C   . GLY D 2 284 ? 151.928 132.538 188.653 1.00 79.91  ? 300 GLY E C   1 
ATOM   10285 O O   . GLY D 2 284 ? 153.156 132.651 188.727 1.00 79.46  ? 300 GLY E O   1 
ATOM   10286 N N   . GLY D 2 285 ? 151.301 131.387 188.879 1.00 81.91  ? 301 GLY E N   1 
ATOM   10287 C CA  . GLY D 2 285 ? 152.037 130.189 189.229 1.00 82.54  ? 301 GLY E CA  1 
ATOM   10288 C C   . GLY D 2 285 ? 152.131 129.168 188.114 1.00 83.41  ? 301 GLY E C   1 
ATOM   10289 O O   . GLY D 2 285 ? 152.847 128.171 188.245 1.00 80.45  ? 301 GLY E O   1 
ATOM   10290 N N   . ASP D 2 286 ? 151.425 129.400 187.012 1.00 85.38  ? 302 ASP E N   1 
ATOM   10291 C CA  . ASP D 2 286 ? 151.389 128.461 185.902 1.00 84.38  ? 302 ASP E CA  1 
ATOM   10292 C C   . ASP D 2 286 ? 152.174 129.003 184.713 1.00 79.26  ? 302 ASP E C   1 
ATOM   10293 O O   . ASP D 2 286 ? 152.439 130.203 184.604 1.00 77.91  ? 302 ASP E O   1 
ATOM   10294 C CB  . ASP D 2 286 ? 149.946 128.146 185.487 1.00 85.30  ? 302 ASP E CB  1 
ATOM   10295 C CG  . ASP D 2 286 ? 149.297 129.272 184.707 1.00 83.34  ? 302 ASP E CG  1 
ATOM   10296 O OD1 . ASP D 2 286 ? 149.503 130.447 185.067 1.00 80.35  ? 302 ASP E OD1 1 
ATOM   10297 O OD2 . ASP D 2 286 ? 148.578 128.978 183.730 1.00 84.00  ? 302 ASP E OD2 1 
ATOM   10298 N N   . LEU D 2 287 ? 152.541 128.091 183.818 1.00 76.52  ? 303 LEU E N   1 
ATOM   10299 C CA  . LEU D 2 287 ? 153.411 128.388 182.690 1.00 71.95  ? 303 LEU E CA  1 
ATOM   10300 C C   . LEU D 2 287 ? 152.590 128.664 181.437 1.00 73.37  ? 303 LEU E C   1 
ATOM   10301 O O   . LEU D 2 287 ? 151.623 127.956 181.145 1.00 79.81  ? 303 LEU E O   1 
ATOM   10302 C CB  . LEU D 2 287 ? 154.370 127.223 182.434 1.00 69.60  ? 303 LEU E CB  1 
ATOM   10303 C CG  . LEU D 2 287 ? 155.512 127.448 181.444 1.00 64.15  ? 303 LEU E CG  1 
ATOM   10304 C CD1 . LEU D 2 287 ? 156.219 128.752 181.742 1.00 66.13  ? 303 LEU E CD1 1 
ATOM   10305 C CD2 . LEU D 2 287 ? 156.490 126.288 181.479 1.00 62.78  ? 303 LEU E CD2 1 
ATOM   10306 N N   . TYR D 2 288 ? 152.982 129.700 180.700 1.00 67.80  ? 304 TYR E N   1 
ATOM   10307 C CA  . TYR D 2 288 ? 152.382 130.030 179.415 1.00 66.61  ? 304 TYR E CA  1 
ATOM   10308 C C   . TYR D 2 288 ? 153.461 129.954 178.346 1.00 67.27  ? 304 TYR E C   1 
ATOM   10309 O O   . TYR D 2 288 ? 154.515 130.582 178.478 1.00 70.12  ? 304 TYR E O   1 
ATOM   10310 C CB  . TYR D 2 288 ? 151.747 131.422 179.439 1.00 66.53  ? 304 TYR E CB  1 
ATOM   10311 C CG  . TYR D 2 288 ? 150.406 131.464 180.134 1.00 71.75  ? 304 TYR E CG  1 
ATOM   10312 C CD1 . TYR D 2 288 ? 149.247 131.085 179.474 1.00 75.07  ? 304 TYR E CD1 1 
ATOM   10313 C CD2 . TYR D 2 288 ? 150.302 131.872 181.455 1.00 75.80  ? 304 TYR E CD2 1 
ATOM   10314 C CE1 . TYR D 2 288 ? 148.021 131.121 180.106 1.00 78.68  ? 304 TYR E CE1 1 
ATOM   10315 C CE2 . TYR D 2 288 ? 149.080 131.910 182.097 1.00 77.39  ? 304 TYR E CE2 1 
ATOM   10316 C CZ  . TYR D 2 288 ? 147.944 131.533 181.418 1.00 80.45  ? 304 TYR E CZ  1 
ATOM   10317 O OH  . TYR D 2 288 ? 146.725 131.569 182.054 1.00 84.44  ? 304 TYR E OH  1 
ATOM   10318 N N   . VAL D 2 289 ? 153.198 129.186 177.292 1.00 69.80  ? 305 VAL E N   1 
ATOM   10319 C CA  . VAL D 2 289 ? 154.190 128.888 176.267 1.00 70.24  ? 305 VAL E CA  1 
ATOM   10320 C C   . VAL D 2 289 ? 153.594 129.198 174.901 1.00 73.79  ? 305 VAL E C   1 
ATOM   10321 O O   . VAL D 2 289 ? 152.452 128.819 174.618 1.00 84.64  ? 305 VAL E O   1 
ATOM   10322 C CB  . VAL D 2 289 ? 154.651 127.420 176.336 1.00 71.16  ? 305 VAL E CB  1 
ATOM   10323 C CG1 . VAL D 2 289 ? 155.615 127.122 175.220 1.00 71.98  ? 305 VAL E CG1 1 
ATOM   10324 C CG2 . VAL D 2 289 ? 155.293 127.125 177.680 1.00 69.69  ? 305 VAL E CG2 1 
ATOM   10325 N N   . VAL D 2 290 ? 154.362 129.887 174.060 1.00 68.02  ? 306 VAL E N   1 
ATOM   10326 C CA  . VAL D 2 290 ? 153.970 130.199 172.691 1.00 71.71  ? 306 VAL E CA  1 
ATOM   10327 C C   . VAL D 2 290 ? 154.870 129.413 171.749 1.00 78.85  ? 306 VAL E C   1 
ATOM   10328 O O   . VAL D 2 290 ? 156.100 129.503 171.837 1.00 79.38  ? 306 VAL E O   1 
ATOM   10329 C CB  . VAL D 2 290 ? 154.061 131.707 172.405 1.00 66.88  ? 306 VAL E CB  1 
ATOM   10330 C CG1 . VAL D 2 290 ? 154.083 131.963 170.907 1.00 66.64  ? 306 VAL E CG1 1 
ATOM   10331 C CG2 . VAL D 2 290 ? 152.905 132.440 173.056 1.00 70.84  ? 306 VAL E CG2 1 
ATOM   10332 N N   . GLY D 2 291 ? 154.260 128.644 170.852 1.00 85.89  ? 307 GLY E N   1 
ATOM   10333 C CA  . GLY D 2 291 ? 155.021 127.832 169.924 1.00 89.17  ? 307 GLY E CA  1 
ATOM   10334 C C   . GLY D 2 291 ? 154.384 127.722 168.555 1.00 95.55  ? 307 GLY E C   1 
ATOM   10335 O O   . GLY D 2 291 ? 153.741 128.664 168.083 1.00 94.85  ? 307 GLY E O   1 
ATOM   10336 N N   . GLY D 2 292 ? 154.556 126.574 167.907 1.00 98.03  ? 308 GLY E N   1 
ATOM   10337 C CA  . GLY D 2 292 ? 154.011 126.369 166.581 1.00 103.02 ? 308 GLY E CA  1 
ATOM   10338 C C   . GLY D 2 292 ? 155.055 125.913 165.586 1.00 110.06 ? 308 GLY E C   1 
ATOM   10339 O O   . GLY D 2 292 ? 156.257 126.018 165.846 1.00 109.21 ? 308 GLY E O   1 
ATOM   10340 N N   . SER D 2 293 ? 154.611 125.400 164.444 1.00 114.14 ? 309 SER E N   1 
ATOM   10341 C CA  . SER D 2 293 ? 155.506 124.918 163.404 1.00 115.20 ? 309 SER E CA  1 
ATOM   10342 C C   . SER D 2 293 ? 155.569 125.912 162.252 1.00 116.27 ? 309 SER E C   1 
ATOM   10343 O O   . SER D 2 293 ? 154.607 126.633 161.974 1.00 114.02 ? 309 SER E O   1 
ATOM   10344 C CB  . SER D 2 293 ? 155.059 123.549 162.888 1.00 111.68 ? 309 SER E CB  1 
ATOM   10345 O OG  . SER D 2 293 ? 156.001 123.017 161.973 1.00 115.09 ? 309 SER E OG  1 
ATOM   10346 N N   . ILE D 2 294 ? 156.720 125.944 161.587 1.00 117.31 ? 310 ILE E N   1 
ATOM   10347 C CA  . ILE D 2 294 ? 156.905 126.846 160.446 1.00 117.52 ? 310 ILE E CA  1 
ATOM   10348 C C   . ILE D 2 294 ? 155.930 126.459 159.341 1.00 117.94 ? 310 ILE E C   1 
ATOM   10349 O O   . ILE D 2 294 ? 155.762 125.255 159.059 1.00 118.31 ? 310 ILE E O   1 
ATOM   10350 C CB  . ILE D 2 294 ? 158.358 126.786 159.944 1.00 118.14 ? 310 ILE E CB  1 
ATOM   10351 C CG1 . ILE D 2 294 ? 159.307 126.479 161.103 1.00 118.32 ? 310 ILE E CG1 1 
ATOM   10352 C CG2 . ILE D 2 294 ? 158.755 128.090 159.270 1.00 118.86 ? 310 ILE E CG2 1 
ATOM   10353 C CD1 . ILE D 2 294 ? 160.733 126.211 160.670 1.00 118.06 ? 310 ILE E CD1 1 
ATOM   10354 N N   . PRO D 2 295 ? 155.261 127.414 158.681 1.00 118.17 ? 311 PRO E N   1 
ATOM   10355 C CA  . PRO D 2 295 ? 155.293 128.862 158.914 1.00 117.19 ? 311 PRO E CA  1 
ATOM   10356 C C   . PRO D 2 295 ? 154.092 129.375 159.702 1.00 115.76 ? 311 PRO E C   1 
ATOM   10357 O O   . PRO D 2 295 ? 153.541 130.419 159.366 1.00 113.38 ? 311 PRO E O   1 
ATOM   10358 C CB  . PRO D 2 295 ? 155.300 129.417 157.489 1.00 117.51 ? 311 PRO E CB  1 
ATOM   10359 C CG  . PRO D 2 295 ? 154.385 128.467 156.759 1.00 118.03 ? 311 PRO E CG  1 
ATOM   10360 C CD  . PRO D 2 295 ? 154.627 127.103 157.385 1.00 117.29 ? 311 PRO E CD  1 
ATOM   10361 N N   . ARG D 2 296 ? 153.655 128.676 160.747 1.00 114.51 ? 312 ARG E N   1 
ATOM   10362 C CA  . ARG D 2 296 ? 152.504 129.084 161.552 1.00 112.81 ? 312 ARG E CA  1 
ATOM   10363 C C   . ARG D 2 296 ? 152.876 129.030 163.029 1.00 110.52 ? 312 ARG E C   1 
ATOM   10364 O O   . ARG D 2 296 ? 152.378 128.184 163.781 1.00 107.32 ? 312 ARG E O   1 
ATOM   10365 C CB  . ARG D 2 296 ? 151.296 128.195 161.253 1.00 114.88 ? 312 ARG E CB  1 
ATOM   10366 C CG  . ARG D 2 296 ? 149.955 128.787 161.647 1.00 115.39 ? 312 ARG E CG  1 
ATOM   10367 C CD  . ARG D 2 296 ? 148.894 127.702 161.733 1.00 115.44 ? 312 ARG E CD  1 
ATOM   10368 N NE  . ARG D 2 296 ? 147.546 128.252 161.816 1.00 116.45 ? 312 ARG E NE  1 
ATOM   10369 C CZ  . ARG D 2 296 ? 146.590 127.772 162.599 1.00 116.44 ? 312 ARG E CZ  1 
ATOM   10370 N NH1 . ARG D 2 296 ? 146.799 126.730 163.387 1.00 115.88 ? 312 ARG E NH1 1 
ATOM   10371 N NH2 . ARG D 2 296 ? 145.393 128.352 162.590 1.00 113.89 ? 312 ARG E NH2 1 
ATOM   10372 N N   . PRO D 2 297 ? 153.760 129.929 163.483 1.00 110.12 ? 313 PRO E N   1 
ATOM   10373 C CA  . PRO D 2 297 ? 154.226 129.904 164.879 1.00 104.21 ? 313 PRO E CA  1 
ATOM   10374 C C   . PRO D 2 297 ? 153.369 130.771 165.801 1.00 102.98 ? 313 PRO E C   1 
ATOM   10375 O O   . PRO D 2 297 ? 153.823 131.782 166.346 1.00 100.50 ? 313 PRO E O   1 
ATOM   10376 C CB  . PRO D 2 297 ? 155.656 130.435 164.745 1.00 102.20 ? 313 PRO E CB  1 
ATOM   10377 C CG  . PRO D 2 297 ? 155.569 131.421 163.597 1.00 103.97 ? 313 PRO E CG  1 
ATOM   10378 C CD  . PRO D 2 297 ? 154.375 131.041 162.738 1.00 108.41 ? 313 PRO E CD  1 
ATOM   10379 N N   . ARG D 2 298 ? 152.110 130.377 165.979 1.00 102.83 ? 314 ARG E N   1 
ATOM   10380 C CA  . ARG D 2 298 ? 151.191 131.130 166.827 1.00 98.91  ? 314 ARG E CA  1 
ATOM   10381 C C   . ARG D 2 298 ? 150.330 130.189 167.655 1.00 94.67  ? 314 ARG E C   1 
ATOM   10382 O O   . ARG D 2 298 ? 149.202 130.521 168.030 1.00 93.37  ? 314 ARG E O   1 
ATOM   10383 C CB  . ARG D 2 298 ? 150.314 132.065 165.997 1.00 97.48  ? 314 ARG E CB  1 
ATOM   10384 C CG  . ARG D 2 298 ? 149.572 131.380 164.865 1.00 100.02 ? 314 ARG E CG  1 
ATOM   10385 C CD  . ARG D 2 298 ? 149.203 132.368 163.770 1.00 99.56  ? 314 ARG E CD  1 
ATOM   10386 N NE  . ARG D 2 298 ? 147.850 132.890 163.923 1.00 98.68  ? 314 ARG E NE  1 
ATOM   10387 C CZ  . ARG D 2 298 ? 146.741 132.177 163.777 1.00 103.75 ? 314 ARG E CZ  1 
ATOM   10388 N NH1 . ARG D 2 298 ? 146.778 130.894 163.455 1.00 107.20 ? 314 ARG E NH1 1 
ATOM   10389 N NH2 . ARG D 2 298 ? 145.563 132.768 163.955 1.00 102.21 ? 314 ARG E NH2 1 
ATOM   10390 N N   . ARG D 2 299 ? 150.851 129.004 167.963 1.00 94.72  ? 315 ARG E N   1 
ATOM   10391 C CA  . ARG D 2 299 ? 150.097 128.002 168.717 1.00 97.99  ? 315 ARG E CA  1 
ATOM   10392 C C   . ARG D 2 299 ? 150.350 128.218 170.204 1.00 97.96  ? 315 ARG E C   1 
ATOM   10393 O O   . ARG D 2 299 ? 151.345 127.758 170.764 1.00 94.96  ? 315 ARG E O   1 
ATOM   10394 C CB  . ARG D 2 299 ? 150.485 126.596 168.279 1.00 101.26 ? 315 ARG E CB  1 
ATOM   10395 C CG  . ARG D 2 299 ? 149.301 125.687 167.997 1.00 103.76 ? 315 ARG E CG  1 
ATOM   10396 C CD  . ARG D 2 299 ? 149.697 124.220 168.070 1.00 106.27 ? 315 ARG E CD  1 
ATOM   10397 N NE  . ARG D 2 299 ? 150.370 123.780 166.853 1.00 107.33 ? 315 ARG E NE  1 
ATOM   10398 C CZ  . ARG D 2 299 ? 150.316 122.546 166.370 1.00 107.26 ? 315 ARG E CZ  1 
ATOM   10399 N NH1 . ARG D 2 299 ? 149.617 121.597 166.972 1.00 106.60 ? 315 ARG E NH1 1 
ATOM   10400 N NH2 . ARG D 2 299 ? 150.979 122.257 165.254 1.00 104.99 ? 315 ARG E NH2 1 
ATOM   10401 N N   . MET D 2 300 ? 149.427 128.922 170.854 1.00 98.83  ? 316 MET E N   1 
ATOM   10402 C CA  . MET D 2 300 ? 149.512 129.119 172.294 1.00 96.01  ? 316 MET E CA  1 
ATOM   10403 C C   . MET D 2 300 ? 149.136 127.825 173.004 1.00 102.58 ? 316 MET E C   1 
ATOM   10404 O O   . MET D 2 300 ? 148.221 127.112 172.582 1.00 104.89 ? 316 MET E O   1 
ATOM   10405 C CB  . MET D 2 300 ? 148.589 130.259 172.727 1.00 91.61  ? 316 MET E CB  1 
ATOM   10406 C CG  . MET D 2 300 ? 148.657 130.619 174.201 1.00 87.98  ? 316 MET E CG  1 
ATOM   10407 S SD  . MET D 2 300 ? 149.542 132.168 174.461 1.00 83.82  ? 316 MET E SD  1 
ATOM   10408 C CE  . MET D 2 300 ? 149.601 132.236 176.245 1.00 78.60  ? 316 MET E CE  1 
ATOM   10409 N N   . TRP D 2 301 ? 149.849 127.516 174.083 1.00 100.14 ? 317 TRP E N   1 
ATOM   10410 C CA  . TRP D 2 301 ? 149.743 126.209 174.719 1.00 102.56 ? 317 TRP E CA  1 
ATOM   10411 C C   . TRP D 2 301 ? 148.668 126.216 175.798 1.00 108.35 ? 317 TRP E C   1 
ATOM   10412 O O   . TRP D 2 301 ? 148.694 127.052 176.708 1.00 103.69 ? 317 TRP E O   1 
ATOM   10413 C CB  . TRP D 2 301 ? 151.083 125.778 175.311 1.00 99.23  ? 317 TRP E CB  1 
ATOM   10414 C CG  . TRP D 2 301 ? 151.253 124.293 175.304 1.00 110.12 ? 317 TRP E CG  1 
ATOM   10415 C CD1 . TRP D 2 301 ? 151.506 123.492 176.379 1.00 114.33 ? 317 TRP E CD1 1 
ATOM   10416 C CD2 . TRP D 2 301 ? 151.172 123.424 174.166 1.00 112.60 ? 317 TRP E CD2 1 
ATOM   10417 N NE1 . TRP D 2 301 ? 151.592 122.180 175.982 1.00 116.64 ? 317 TRP E NE1 1 
ATOM   10418 C CE2 . TRP D 2 301 ? 151.391 122.112 174.628 1.00 115.21 ? 317 TRP E CE2 1 
ATOM   10419 C CE3 . TRP D 2 301 ? 150.939 123.629 172.802 1.00 109.38 ? 317 TRP E CE3 1 
ATOM   10420 C CZ2 . TRP D 2 301 ? 151.382 121.010 173.776 1.00 113.54 ? 317 TRP E CZ2 1 
ATOM   10421 C CZ3 . TRP D 2 301 ? 150.931 122.536 171.960 1.00 112.44 ? 317 TRP E CZ3 1 
ATOM   10422 C CH2 . TRP D 2 301 ? 151.151 121.243 172.449 1.00 113.43 ? 317 TRP E CH2 1 
ATOM   10423 N N   . LYS D 2 302 ? 147.727 125.275 175.691 1.00 116.41 ? 318 LYS E N   1 
ATOM   10424 C CA  . LYS D 2 302 ? 146.702 125.048 176.699 1.00 114.36 ? 318 LYS E CA  1 
ATOM   10425 C C   . LYS D 2 302 ? 146.662 123.620 177.218 1.00 115.66 ? 318 LYS E C   1 
ATOM   10426 O O   . LYS D 2 302 ? 145.924 123.352 178.173 1.00 115.76 ? 318 LYS E O   1 
ATOM   10427 C CB  . LYS D 2 302 ? 145.307 125.407 176.157 1.00 112.36 ? 318 LYS E CB  1 
ATOM   10428 C CG  . LYS D 2 302 ? 144.637 124.366 175.244 1.00 118.71 ? 318 LYS E CG  1 
ATOM   10429 C CD  . LYS D 2 302 ? 145.526 123.879 174.103 1.00 117.62 ? 318 LYS E CD  1 
ATOM   10430 C CE  . LYS D 2 302 ? 144.748 123.047 173.101 1.00 119.94 ? 318 LYS E CE  1 
ATOM   10431 N NZ  . LYS D 2 302 ? 145.644 122.138 172.332 1.00 120.20 ? 318 LYS E NZ  1 
ATOM   10432 N N   . CYS D 2 303 ? 147.420 122.701 176.625 1.00 115.51 ? 319 CYS E N   1 
ATOM   10433 C CA  . CYS D 2 303 ? 147.319 121.281 176.928 1.00 120.35 ? 319 CYS E CA  1 
ATOM   10434 C C   . CYS D 2 303 ? 148.645 120.762 177.458 1.00 118.58 ? 319 CYS E C   1 
ATOM   10435 O O   . CYS D 2 303 ? 149.695 120.993 176.850 1.00 116.97 ? 319 CYS E O   1 
ATOM   10436 C CB  . CYS D 2 303 ? 146.906 120.486 175.685 1.00 123.35 ? 319 CYS E CB  1 
ATOM   10437 S SG  . CYS D 2 303 ? 147.019 118.691 175.868 1.00 123.12 ? 319 CYS E SG  1 
ATOM   10438 N N   . ASN D 2 304 ? 148.587 120.061 178.582 1.00 118.79 ? 320 ASN E N   1 
ATOM   10439 C CA  . ASN D 2 304 ? 149.720 119.340 179.158 1.00 120.07 ? 320 ASN E CA  1 
ATOM   10440 C C   . ASN D 2 304 ? 149.171 118.473 180.286 1.00 122.29 ? 320 ASN E C   1 
ATOM   10441 O O   . ASN D 2 304 ? 147.959 118.447 180.533 1.00 122.61 ? 320 ASN E O   1 
ATOM   10442 C CB  . ASN D 2 304 ? 150.813 120.298 179.636 1.00 117.89 ? 320 ASN E CB  1 
ATOM   10443 C CG  . ASN D 2 304 ? 152.169 119.971 179.043 1.00 115.66 ? 320 ASN E CG  1 
ATOM   10444 O OD1 . ASN D 2 304 ? 152.605 118.821 179.061 1.00 115.60 ? 320 ASN E OD1 1 
ATOM   10445 N ND2 . ASN D 2 304 ? 152.842 120.983 178.509 1.00 112.43 ? 320 ASN E ND2 1 
ATOM   10446 N N   . ASN D 2 305 ? 150.060 117.759 180.976 1.00 124.77 ? 321 ASN E N   1 
ATOM   10447 C CA  . ASN D 2 305 ? 149.639 116.902 182.077 1.00 126.04 ? 321 ASN E CA  1 
ATOM   10448 C C   . ASN D 2 305 ? 149.329 117.680 183.350 1.00 127.13 ? 321 ASN E C   1 
ATOM   10449 O O   . ASN D 2 305 ? 148.810 117.090 184.304 1.00 125.52 ? 321 ASN E O   1 
ATOM   10450 C CB  . ASN D 2 305 ? 150.712 115.849 182.369 1.00 124.68 ? 321 ASN E CB  1 
ATOM   10451 C CG  . ASN D 2 305 ? 152.080 116.457 182.600 1.00 123.97 ? 321 ASN E CG  1 
ATOM   10452 O OD1 . ASN D 2 305 ? 152.418 116.846 183.718 1.00 124.03 ? 321 ASN E OD1 1 
ATOM   10453 N ND2 . ASN D 2 305 ? 152.879 116.538 181.542 1.00 119.55 ? 321 ASN E ND2 1 
ATOM   10454 N N   . ALA D 2 306 ? 149.630 118.977 183.389 1.00 127.34 ? 322 ALA E N   1 
ATOM   10455 C CA  . ALA D 2 306 ? 149.339 119.808 184.550 1.00 128.25 ? 322 ALA E CA  1 
ATOM   10456 C C   . ALA D 2 306 ? 148.020 120.558 184.437 1.00 128.12 ? 322 ALA E C   1 
ATOM   10457 O O   . ALA D 2 306 ? 147.475 120.986 185.459 1.00 125.03 ? 322 ALA E O   1 
ATOM   10458 C CB  . ALA D 2 306 ? 150.471 120.814 184.780 1.00 124.99 ? 322 ALA E CB  1 
ATOM   10459 N N   . THR D 2 307 ? 147.498 120.730 183.222 1.00 127.18 ? 323 THR E N   1 
ATOM   10460 C CA  . THR D 2 307 ? 146.236 121.426 183.011 1.00 126.28 ? 323 THR E CA  1 
ATOM   10461 C C   . THR D 2 307 ? 145.117 120.518 182.519 1.00 129.65 ? 323 THR E C   1 
ATOM   10462 O O   . THR D 2 307 ? 143.947 120.905 182.616 1.00 129.85 ? 323 THR E O   1 
ATOM   10463 C CB  . THR D 2 307 ? 146.422 122.572 182.009 1.00 124.49 ? 323 THR E CB  1 
ATOM   10464 O OG1 . THR D 2 307 ? 145.141 123.063 181.595 1.00 123.55 ? 323 THR E OG1 1 
ATOM   10465 C CG2 . THR D 2 307 ? 147.193 122.088 180.795 1.00 123.01 ? 323 THR E CG2 1 
ATOM   10466 N N   . VAL D 2 308 ? 145.456 119.327 182.011 1.00 131.01 ? 324 VAL E N   1 
ATOM   10467 C CA  . VAL D 2 308 ? 144.535 118.315 181.486 1.00 131.93 ? 324 VAL E CA  1 
ATOM   10468 C C   . VAL D 2 308 ? 143.333 118.935 180.778 1.00 130.92 ? 324 VAL E C   1 
ATOM   10469 O O   . VAL D 2 308 ? 142.181 118.565 181.036 1.00 130.27 ? 324 VAL E O   1 
ATOM   10470 C CB  . VAL D 2 308 ? 144.089 117.332 182.593 1.00 132.04 ? 324 VAL E CB  1 
ATOM   10471 C CG1 . VAL D 2 308 ? 145.278 116.516 183.080 1.00 128.88 ? 324 VAL E CG1 1 
ATOM   10472 C CG2 . VAL D 2 308 ? 143.418 118.045 183.771 1.00 129.45 ? 324 VAL E CG2 1 
ATOM   10473 N N   . ASP D 2 309 ? 143.595 119.862 179.860 1.00 131.37 ? 325 ASP E N   1 
ATOM   10474 C CA  . ASP D 2 309 ? 142.542 120.518 179.098 1.00 132.57 ? 325 ASP E CA  1 
ATOM   10475 C C   . ASP D 2 309 ? 143.015 120.715 177.665 1.00 131.02 ? 325 ASP E C   1 
ATOM   10476 O O   . ASP D 2 309 ? 144.213 120.696 177.378 1.00 128.56 ? 325 ASP E O   1 
ATOM   10477 C CB  . ASP D 2 309 ? 142.147 121.864 179.721 1.00 132.73 ? 325 ASP E CB  1 
ATOM   10478 C CG  . ASP D 2 309 ? 141.156 121.711 180.858 1.00 133.46 ? 325 ASP E CG  1 
ATOM   10479 O OD1 . ASP D 2 309 ? 140.270 120.836 180.763 1.00 132.70 ? 325 ASP E OD1 1 
ATOM   10480 O OD2 . ASP D 2 309 ? 141.263 122.466 181.848 1.00 132.12 ? 325 ASP E OD2 1 
ATOM   10481 N N   . TRP D 2 310 ? 142.051 120.897 176.757 1.00 130.91 ? 326 TRP E N   1 
ATOM   10482 C CA  . TRP D 2 310 ? 142.364 121.092 175.346 1.00 129.22 ? 326 TRP E CA  1 
ATOM   10483 C C   . TRP D 2 310 ? 141.485 122.167 174.716 1.00 128.71 ? 326 TRP E C   1 
ATOM   10484 O O   . TRP D 2 310 ? 141.145 122.078 173.531 1.00 126.77 ? 326 TRP E O   1 
ATOM   10485 C CB  . TRP D 2 310 ? 142.221 119.782 174.562 1.00 128.15 ? 326 TRP E CB  1 
ATOM   10486 C CG  . TRP D 2 310 ? 140.935 119.042 174.816 1.00 130.14 ? 326 TRP E CG  1 
ATOM   10487 C CD1 . TRP D 2 310 ? 139.701 119.586 175.032 1.00 130.18 ? 326 TRP E CD1 1 
ATOM   10488 C CD2 . TRP D 2 310 ? 140.759 117.620 174.865 1.00 131.21 ? 326 TRP E CD2 1 
ATOM   10489 N NE1 . TRP D 2 310 ? 138.771 118.592 175.220 1.00 129.37 ? 326 TRP E NE1 1 
ATOM   10490 C CE2 . TRP D 2 310 ? 139.394 117.376 175.121 1.00 131.40 ? 326 TRP E CE2 1 
ATOM   10491 C CE3 . TRP D 2 310 ? 141.622 116.530 174.720 1.00 129.80 ? 326 TRP E CE3 1 
ATOM   10492 C CZ2 . TRP D 2 310 ? 138.874 116.089 175.235 1.00 130.36 ? 326 TRP E CZ2 1 
ATOM   10493 C CZ3 . TRP D 2 310 ? 141.103 115.252 174.833 1.00 126.43 ? 326 TRP E CZ3 1 
ATOM   10494 C CH2 . TRP D 2 310 ? 139.743 115.043 175.089 1.00 127.27 ? 326 TRP E CH2 1 
ATOM   10495 N N   . GLU D 2 311 ? 141.108 123.186 175.483 1.00 129.73 ? 327 GLU E N   1 
ATOM   10496 C CA  . GLU D 2 311 ? 140.136 124.171 175.008 1.00 128.86 ? 327 GLU E CA  1 
ATOM   10497 C C   . GLU D 2 311 ? 140.797 125.335 174.273 1.00 126.79 ? 327 GLU E C   1 
ATOM   10498 O O   . GLU D 2 311 ? 140.516 126.499 174.552 1.00 125.23 ? 327 GLU E O   1 
ATOM   10499 C CB  . GLU D 2 311 ? 139.297 124.671 176.177 1.00 128.97 ? 327 GLU E CB  1 
ATOM   10500 C CG  . GLU D 2 311 ? 138.391 123.613 176.788 1.00 129.19 ? 327 GLU E CG  1 
ATOM   10501 C CD  . GLU D 2 311 ? 139.077 122.818 177.882 1.00 130.60 ? 327 GLU E CD  1 
ATOM   10502 O OE1 . GLU D 2 311 ? 139.234 123.353 178.999 1.00 130.03 ? 327 GLU E OE1 1 
ATOM   10503 O OE2 . GLU D 2 311 ? 139.460 121.658 177.623 1.00 130.87 ? 327 GLU E OE2 1 
ATOM   10504 N N   . TRP D 2 312 ? 141.675 125.009 173.318 1.00 124.76 ? 328 TRP E N   1 
ATOM   10505 C CA  . TRP D 2 312 ? 142.171 125.943 172.309 1.00 120.11 ? 328 TRP E CA  1 
ATOM   10506 C C   . TRP D 2 312 ? 142.499 127.333 172.841 1.00 117.33 ? 328 TRP E C   1 
ATOM   10507 O O   . TRP D 2 312 ? 141.808 128.297 172.495 1.00 112.83 ? 328 TRP E O   1 
ATOM   10508 C CB  . TRP D 2 312 ? 141.158 126.073 171.167 1.00 122.47 ? 328 TRP E CB  1 
ATOM   10509 C CG  . TRP D 2 312 ? 140.876 124.790 170.445 1.00 127.41 ? 328 TRP E CG  1 
ATOM   10510 C CD1 . TRP D 2 312 ? 141.631 124.223 169.459 1.00 128.86 ? 328 TRP E CD1 1 
ATOM   10511 C CD2 . TRP D 2 312 ? 139.753 123.923 170.640 1.00 128.06 ? 328 TRP E CD2 1 
ATOM   10512 N NE1 . TRP D 2 312 ? 141.051 123.052 169.034 1.00 130.17 ? 328 TRP E NE1 1 
ATOM   10513 C CE2 . TRP D 2 312 ? 139.897 122.846 169.743 1.00 129.33 ? 328 TRP E CE2 1 
ATOM   10514 C CE3 . TRP D 2 312 ? 138.642 123.950 171.488 1.00 125.13 ? 328 TRP E CE3 1 
ATOM   10515 C CZ2 . TRP D 2 312 ? 138.972 121.807 169.670 1.00 126.69 ? 328 TRP E CZ2 1 
ATOM   10516 C CZ3 . TRP D 2 312 ? 137.725 122.918 171.414 1.00 126.32 ? 328 TRP E CZ3 1 
ATOM   10517 C CH2 . TRP D 2 312 ? 137.896 121.861 170.511 1.00 126.69 ? 328 TRP E CH2 1 
ATOM   10518 N N   . CYS D 2 313 ? 143.506 127.446 173.710 1.00 113.98 ? 329 CYS E N   1 
ATOM   10519 C CA  . CYS D 2 313 ? 143.970 128.757 174.154 1.00 103.95 ? 329 CYS E CA  1 
ATOM   10520 C C   . CYS D 2 313 ? 144.195 129.662 172.954 1.00 97.38  ? 329 CYS E C   1 
ATOM   10521 O O   . CYS D 2 313 ? 144.910 129.295 172.017 1.00 95.67  ? 329 CYS E O   1 
ATOM   10522 C CB  . CYS D 2 313 ? 145.259 128.622 174.964 1.00 99.63  ? 329 CYS E CB  1 
ATOM   10523 S SG  . CYS D 2 313 ? 145.471 129.872 176.254 1.00 88.96  ? 329 CYS E SG  1 
ATOM   10524 N N   . ALA D 2 314 ? 143.570 130.840 172.989 1.00 93.76  ? 330 ALA E N   1 
ATOM   10525 C CA  . ALA D 2 314 ? 143.461 131.744 171.849 1.00 93.47  ? 330 ALA E CA  1 
ATOM   10526 C C   . ALA D 2 314 ? 144.805 131.954 171.163 1.00 92.86  ? 330 ALA E C   1 
ATOM   10527 O O   . ALA D 2 314 ? 145.719 132.553 171.746 1.00 89.19  ? 330 ALA E O   1 
ATOM   10528 C CB  . ALA D 2 314 ? 142.875 133.085 172.292 1.00 89.32  ? 330 ALA E CB  1 
ATOM   10529 N N   . PRO D 2 315 ? 144.965 131.461 169.936 1.00 93.68  ? 331 PRO E N   1 
ATOM   10530 C CA  . PRO D 2 315 ? 146.228 131.659 169.219 1.00 90.91  ? 331 PRO E CA  1 
ATOM   10531 C C   . PRO D 2 315 ? 146.471 133.130 168.923 1.00 85.34  ? 331 PRO E C   1 
ATOM   10532 O O   . PRO D 2 315 ? 145.538 133.925 168.796 1.00 85.72  ? 331 PRO E O   1 
ATOM   10533 C CB  . PRO D 2 315 ? 146.031 130.855 167.928 1.00 94.05  ? 331 PRO E CB  1 
ATOM   10534 C CG  . PRO D 2 315 ? 144.967 129.859 168.264 1.00 92.36  ? 331 PRO E CG  1 
ATOM   10535 C CD  . PRO D 2 315 ? 144.044 130.589 169.190 1.00 94.19  ? 331 PRO E CD  1 
ATOM   10536 N N   . LEU D 2 316 ? 147.746 133.486 168.823 1.00 83.36  ? 332 LEU E N   1 
ATOM   10537 C CA  . LEU D 2 316 ? 148.104 134.863 168.526 1.00 82.66  ? 332 LEU E CA  1 
ATOM   10538 C C   . LEU D 2 316 ? 147.594 135.246 167.139 1.00 84.40  ? 332 LEU E C   1 
ATOM   10539 O O   . LEU D 2 316 ? 147.730 134.466 166.189 1.00 88.91  ? 332 LEU E O   1 
ATOM   10540 C CB  . LEU D 2 316 ? 149.620 135.050 168.596 1.00 83.65  ? 332 LEU E CB  1 
ATOM   10541 C CG  . LEU D 2 316 ? 150.225 135.275 169.981 1.00 74.87  ? 332 LEU E CG  1 
ATOM   10542 C CD1 . LEU D 2 316 ? 150.673 133.958 170.587 1.00 71.18  ? 332 LEU E CD1 1 
ATOM   10543 C CD2 . LEU D 2 316 ? 151.383 136.253 169.900 1.00 66.50  ? 332 LEU E CD2 1 
ATOM   10544 N N   . PRO D 2 317 ? 147.004 136.433 166.983 1.00 80.62  ? 333 PRO E N   1 
ATOM   10545 C CA  . PRO D 2 317 ? 146.525 136.860 165.665 1.00 82.44  ? 333 PRO E CA  1 
ATOM   10546 C C   . PRO D 2 317 ? 147.620 137.360 164.737 1.00 86.38  ? 333 PRO E C   1 
ATOM   10547 O O   . PRO D 2 317 ? 147.306 137.833 163.639 1.00 86.35  ? 333 PRO E O   1 
ATOM   10548 C CB  . PRO D 2 317 ? 145.546 137.989 166.014 1.00 82.38  ? 333 PRO E CB  1 
ATOM   10549 C CG  . PRO D 2 317 ? 146.106 138.577 167.260 1.00 80.86  ? 333 PRO E CG  1 
ATOM   10550 C CD  . PRO D 2 317 ? 146.740 137.441 168.025 1.00 79.39  ? 333 PRO E CD  1 
ATOM   10551 N N   . ARG D 2 318 ? 148.885 137.276 165.143 1.00 88.55  ? 334 ARG E N   1 
ATOM   10552 C CA  . ARG D 2 318 ? 150.001 137.707 164.315 1.00 86.03  ? 334 ARG E CA  1 
ATOM   10553 C C   . ARG D 2 318 ? 151.092 136.649 164.355 1.00 86.27  ? 334 ARG E C   1 
ATOM   10554 O O   . ARG D 2 318 ? 151.377 136.080 165.412 1.00 84.45  ? 334 ARG E O   1 
ATOM   10555 C CB  . ARG D 2 318 ? 150.558 139.056 164.784 1.00 77.69  ? 334 ARG E CB  1 
ATOM   10556 C CG  . ARG D 2 318 ? 149.615 140.226 164.559 1.00 76.26  ? 334 ARG E CG  1 
ATOM   10557 C CD  . ARG D 2 318 ? 150.206 141.520 165.087 1.00 74.38  ? 334 ARG E CD  1 
ATOM   10558 N NE  . ARG D 2 318 ? 150.188 142.582 164.087 1.00 75.65  ? 334 ARG E NE  1 
ATOM   10559 C CZ  . ARG D 2 318 ? 151.075 142.710 163.110 1.00 76.63  ? 334 ARG E CZ  1 
ATOM   10560 N NH1 . ARG D 2 318 ? 152.072 141.852 162.964 1.00 76.07  ? 334 ARG E NH1 1 
ATOM   10561 N NH2 . ARG D 2 318 ? 150.960 143.724 162.258 1.00 73.75  ? 334 ARG E NH2 1 
ATOM   10562 N N   . ASP D 2 319 ? 151.697 136.389 163.198 1.00 86.66  ? 335 ASP E N   1 
ATOM   10563 C CA  . ASP D 2 319 ? 152.784 135.420 163.071 1.00 86.78  ? 335 ASP E CA  1 
ATOM   10564 C C   . ASP D 2 319 ? 154.101 136.179 163.186 1.00 84.07  ? 335 ASP E C   1 
ATOM   10565 O O   . ASP D 2 319 ? 154.564 136.791 162.220 1.00 83.75  ? 335 ASP E O   1 
ATOM   10566 C CB  . ASP D 2 319 ? 152.687 134.664 161.750 1.00 94.26  ? 335 ASP E CB  1 
ATOM   10567 C CG  . ASP D 2 319 ? 151.351 133.971 161.571 1.00 101.60 ? 335 ASP E CG  1 
ATOM   10568 O OD1 . ASP D 2 319 ? 150.308 134.652 161.668 1.00 99.47  ? 335 ASP E OD1 1 
ATOM   10569 O OD2 . ASP D 2 319 ? 151.343 132.746 161.331 1.00 107.13 ? 335 ASP E OD2 1 
ATOM   10570 N N   . ARG D 2 320 ? 154.703 136.138 164.371 1.00 79.88  ? 336 ARG E N   1 
ATOM   10571 C CA  . ARG D 2 320 ? 155.938 136.854 164.645 1.00 71.93  ? 336 ARG E CA  1 
ATOM   10572 C C   . ARG D 2 320 ? 156.922 135.936 165.354 1.00 70.75  ? 336 ARG E C   1 
ATOM   10573 O O   . ARG D 2 320 ? 156.542 134.947 165.985 1.00 72.37  ? 336 ARG E O   1 
ATOM   10574 C CB  . ARG D 2 320 ? 155.690 138.106 165.496 1.00 67.59  ? 336 ARG E CB  1 
ATOM   10575 C CG  . ARG D 2 320 ? 154.894 139.191 164.794 1.00 71.01  ? 336 ARG E CG  1 
ATOM   10576 C CD  . ARG D 2 320 ? 154.595 140.342 165.738 1.00 65.12  ? 336 ARG E CD  1 
ATOM   10577 N NE  . ARG D 2 320 ? 154.037 139.874 167.000 1.00 63.31  ? 336 ARG E NE  1 
ATOM   10578 C CZ  . ARG D 2 320 ? 153.676 140.666 168.000 1.00 58.02  ? 336 ARG E CZ  1 
ATOM   10579 N NH1 . ARG D 2 320 ? 153.797 141.980 167.919 1.00 55.73  ? 336 ARG E NH1 1 
ATOM   10580 N NH2 . ARG D 2 320 ? 153.179 140.125 169.108 1.00 58.07  ? 336 ARG E NH2 1 
ATOM   10581 N N   . LEU D 2 321 ? 158.201 136.280 165.236 1.00 68.95  ? 337 LEU E N   1 
ATOM   10582 C CA  . LEU D 2 321 ? 159.281 135.563 165.892 1.00 67.00  ? 337 LEU E CA  1 
ATOM   10583 C C   . LEU D 2 321 ? 160.074 136.526 166.764 1.00 64.52  ? 337 LEU E C   1 
ATOM   10584 O O   . LEU D 2 321 ? 160.120 137.731 166.500 1.00 64.94  ? 337 LEU E O   1 
ATOM   10585 C CB  . LEU D 2 321 ? 160.213 134.898 164.871 1.00 68.53  ? 337 LEU E CB  1 
ATOM   10586 C CG  . LEU D 2 321 ? 160.164 133.372 164.779 1.00 67.82  ? 337 LEU E CG  1 
ATOM   10587 C CD1 . LEU D 2 321 ? 158.811 132.904 164.276 1.00 66.91  ? 337 LEU E CD1 1 
ATOM   10588 C CD2 . LEU D 2 321 ? 161.278 132.858 163.882 1.00 67.52  ? 337 LEU E CD2 1 
ATOM   10589 N N   . GLN D 2 322 ? 160.690 135.980 167.813 1.00 61.02  ? 338 GLN E N   1 
ATOM   10590 C CA  . GLN D 2 322 ? 161.508 136.751 168.750 1.00 60.99  ? 338 GLN E CA  1 
ATOM   10591 C C   . GLN D 2 322 ? 160.713 137.873 169.412 1.00 59.47  ? 338 GLN E C   1 
ATOM   10592 O O   . GLN D 2 322 ? 161.257 138.936 169.719 1.00 58.07  ? 338 GLN E O   1 
ATOM   10593 C CB  . GLN D 2 322 ? 162.755 137.318 168.066 1.00 62.07  ? 338 GLN E CB  1 
ATOM   10594 C CG  . GLN D 2 322 ? 163.870 136.309 167.875 1.00 62.80  ? 338 GLN E CG  1 
ATOM   10595 C CD  . GLN D 2 322 ? 164.668 136.564 166.616 1.00 73.59  ? 338 GLN E CD  1 
ATOM   10596 O OE1 . GLN D 2 322 ? 165.646 137.310 166.628 1.00 75.43  ? 338 GLN E OE1 1 
ATOM   10597 N NE2 . GLN D 2 322 ? 164.254 135.944 165.517 1.00 74.14  ? 338 GLN E NE2 1 
ATOM   10598 N N   . HIS D 2 323 ? 159.423 137.647 169.634 1.00 59.87  ? 339 HIS E N   1 
ATOM   10599 C CA  . HIS D 2 323 ? 158.598 138.612 170.341 1.00 53.63  ? 339 HIS E CA  1 
ATOM   10600 C C   . HIS D 2 323 ? 158.747 138.431 171.849 1.00 52.23  ? 339 HIS E C   1 
ATOM   10601 O O   . HIS D 2 323 ? 159.248 137.413 172.334 1.00 52.02  ? 339 HIS E O   1 
ATOM   10602 C CB  . HIS D 2 323 ? 157.134 138.479 169.921 1.00 51.48  ? 339 HIS E CB  1 
ATOM   10603 C CG  . HIS D 2 323 ? 156.544 137.132 170.197 1.00 52.60  ? 339 HIS E CG  1 
ATOM   10604 N ND1 . HIS D 2 323 ? 157.017 135.977 169.612 1.00 55.88  ? 339 HIS E ND1 1 
ATOM   10605 C CD2 . HIS D 2 323 ? 155.514 136.756 170.990 1.00 54.27  ? 339 HIS E CD2 1 
ATOM   10606 C CE1 . HIS D 2 323 ? 156.308 134.948 170.038 1.00 57.26  ? 339 HIS E CE1 1 
ATOM   10607 N NE2 . HIS D 2 323 ? 155.391 135.393 170.876 1.00 57.91  ? 339 HIS E NE2 1 
ATOM   10608 N N   . THR D 2 324 ? 158.307 139.441 172.592 1.00 49.82  ? 340 THR E N   1 
ATOM   10609 C CA  . THR D 2 324 ? 158.472 139.479 174.039 1.00 47.01  ? 340 THR E CA  1 
ATOM   10610 C C   . THR D 2 324 ? 157.146 139.178 174.722 1.00 46.50  ? 340 THR E C   1 
ATOM   10611 O O   . THR D 2 324 ? 156.140 139.838 174.451 1.00 51.03  ? 340 THR E O   1 
ATOM   10612 C CB  . THR D 2 324 ? 158.992 140.845 174.491 1.00 44.64  ? 340 THR E CB  1 
ATOM   10613 O OG1 . THR D 2 324 ? 159.916 141.352 173.521 1.00 42.33  ? 340 THR E OG1 1 
ATOM   10614 C CG2 . THR D 2 324 ? 159.693 140.730 175.832 1.00 42.05  ? 340 THR E CG2 1 
ATOM   10615 N N   . LEU D 2 325 ? 157.151 138.189 175.611 1.00 46.35  ? 341 LEU E N   1 
ATOM   10616 C CA  . LEU D 2 325 ? 155.982 137.839 176.410 1.00 46.09  ? 341 LEU E CA  1 
ATOM   10617 C C   . LEU D 2 325 ? 156.197 138.348 177.830 1.00 48.86  ? 341 LEU E C   1 
ATOM   10618 O O   . LEU D 2 325 ? 157.031 137.814 178.568 1.00 53.73  ? 341 LEU E O   1 
ATOM   10619 C CB  . LEU D 2 325 ? 155.744 136.331 176.403 1.00 51.00  ? 341 LEU E CB  1 
ATOM   10620 C CG  . LEU D 2 325 ? 154.516 135.817 175.654 1.00 53.28  ? 341 LEU E CG  1 
ATOM   10621 C CD1 . LEU D 2 325 ? 154.643 136.081 174.172 1.00 51.07  ? 341 LEU E CD1 1 
ATOM   10622 C CD2 . LEU D 2 325 ? 154.309 134.337 175.920 1.00 54.03  ? 341 LEU E CD2 1 
ATOM   10623 N N   . VAL D 2 326 ? 155.444 139.377 178.212 1.00 49.17  ? 342 VAL E N   1 
ATOM   10624 C CA  . VAL D 2 326 ? 155.529 139.983 179.535 1.00 48.09  ? 342 VAL E CA  1 
ATOM   10625 C C   . VAL D 2 326 ? 154.164 139.874 180.198 1.00 51.52  ? 342 VAL E C   1 
ATOM   10626 O O   . VAL D 2 326 ? 153.149 140.256 179.606 1.00 56.40  ? 342 VAL E O   1 
ATOM   10627 C CB  . VAL D 2 326 ? 155.983 141.453 179.461 1.00 41.66  ? 342 VAL E CB  1 
ATOM   10628 C CG1 . VAL D 2 326 ? 156.176 142.017 180.855 1.00 42.54  ? 342 VAL E CG1 1 
ATOM   10629 C CG2 . VAL D 2 326 ? 157.260 141.574 178.652 1.00 40.69  ? 342 VAL E CG2 1 
ATOM   10630 N N   . SER D 2 327 ? 154.141 139.359 181.424 1.00 48.68  ? 343 SER E N   1 
ATOM   10631 C CA  . SER D 2 327 ? 152.900 139.177 182.162 1.00 53.48  ? 343 SER E CA  1 
ATOM   10632 C C   . SER D 2 327 ? 152.653 140.372 183.071 1.00 58.99  ? 343 SER E C   1 
ATOM   10633 O O   . SER D 2 327 ? 153.558 140.814 183.786 1.00 59.17  ? 343 SER E O   1 
ATOM   10634 C CB  . SER D 2 327 ? 152.943 137.892 182.988 1.00 60.21  ? 343 SER E CB  1 
ATOM   10635 O OG  . SER D 2 327 ? 153.837 138.015 184.078 1.00 62.19  ? 343 SER E OG  1 
ATOM   10636 N N   . VAL D 2 328 ? 151.429 140.887 183.041 1.00 60.97  ? 344 VAL E N   1 
ATOM   10637 C CA  . VAL D 2 328 ? 151.027 141.996 183.901 1.00 59.01  ? 344 VAL E CA  1 
ATOM   10638 C C   . VAL D 2 328 ? 149.938 141.493 184.840 1.00 65.69  ? 344 VAL E C   1 
ATOM   10639 O O   . VAL D 2 328 ? 148.755 141.502 184.472 1.00 69.26  ? 344 VAL E O   1 
ATOM   10640 C CB  . VAL D 2 328 ? 150.542 143.198 183.077 1.00 56.35  ? 344 VAL E CB  1 
ATOM   10641 C CG1 . VAL D 2 328 ? 150.347 144.410 183.970 1.00 58.72  ? 344 VAL E CG1 1 
ATOM   10642 C CG2 . VAL D 2 328 ? 151.525 143.508 181.962 1.00 52.77  ? 344 VAL E CG2 1 
ATOM   10643 N N   . PRO D 2 329 ? 150.284 141.046 186.049 1.00 68.55  ? 345 PRO E N   1 
ATOM   10644 C CA  . PRO D 2 329 ? 149.255 140.504 186.953 1.00 71.63  ? 345 PRO E CA  1 
ATOM   10645 C C   . PRO D 2 329 ? 148.222 141.527 187.385 1.00 72.28  ? 345 PRO E C   1 
ATOM   10646 O O   . PRO D 2 329 ? 147.140 141.134 187.839 1.00 71.62  ? 345 PRO E O   1 
ATOM   10647 C CB  . PRO D 2 329 ? 150.069 139.990 188.151 1.00 65.80  ? 345 PRO E CB  1 
ATOM   10648 C CG  . PRO D 2 329 ? 151.486 139.924 187.675 1.00 63.98  ? 345 PRO E CG  1 
ATOM   10649 C CD  . PRO D 2 329 ? 151.628 140.990 186.643 1.00 65.48  ? 345 PRO E CD  1 
ATOM   10650 N N   . GLY D 2 330 ? 148.518 142.823 187.269 1.00 71.69  ? 346 GLY E N   1 
ATOM   10651 C CA  . GLY D 2 330 ? 147.535 143.830 187.631 1.00 69.90  ? 346 GLY E CA  1 
ATOM   10652 C C   . GLY D 2 330 ? 146.292 143.771 186.765 1.00 70.84  ? 346 GLY E C   1 
ATOM   10653 O O   . GLY D 2 330 ? 145.171 143.911 187.260 1.00 73.99  ? 346 GLY E O   1 
ATOM   10654 N N   . LYS D 2 331 ? 146.471 143.565 185.463 1.00 71.02  ? 347 LYS E N   1 
ATOM   10655 C CA  . LYS D 2 331 ? 145.363 143.447 184.527 1.00 74.98  ? 347 LYS E CA  1 
ATOM   10656 C C   . LYS D 2 331 ? 145.084 142.005 184.126 1.00 77.89  ? 347 LYS E C   1 
ATOM   10657 O O   . LYS D 2 331 ? 144.226 141.768 183.269 1.00 77.37  ? 347 LYS E O   1 
ATOM   10658 C CB  . LYS D 2 331 ? 145.635 144.290 183.281 1.00 70.80  ? 347 LYS E CB  1 
ATOM   10659 C CG  . LYS D 2 331 ? 146.262 145.642 183.574 1.00 66.07  ? 347 LYS E CG  1 
ATOM   10660 C CD  . LYS D 2 331 ? 146.159 146.585 182.383 1.00 69.03  ? 347 LYS E CD  1 
ATOM   10661 C CE  . LYS D 2 331 ? 146.097 145.830 181.064 1.00 72.14  ? 347 LYS E CE  1 
ATOM   10662 N NZ  . LYS D 2 331 ? 145.574 146.679 179.958 1.00 68.84  ? 347 LYS E NZ  1 
ATOM   10663 N N   . ASP D 2 332 ? 145.783 141.041 184.730 1.00 76.53  ? 348 ASP E N   1 
ATOM   10664 C CA  . ASP D 2 332 ? 145.641 139.624 184.388 1.00 77.39  ? 348 ASP E CA  1 
ATOM   10665 C C   . ASP D 2 332 ? 145.833 139.400 182.891 1.00 77.92  ? 348 ASP E C   1 
ATOM   10666 O O   . ASP D 2 332 ? 145.105 138.637 182.254 1.00 79.91  ? 348 ASP E O   1 
ATOM   10667 C CB  . ASP D 2 332 ? 144.291 139.076 184.854 1.00 82.38  ? 348 ASP E CB  1 
ATOM   10668 C CG  . ASP D 2 332 ? 144.319 137.579 185.088 1.00 87.42  ? 348 ASP E CG  1 
ATOM   10669 O OD1 . ASP D 2 332 ? 145.369 137.063 185.522 1.00 85.81  ? 348 ASP E OD1 1 
ATOM   10670 O OD2 . ASP D 2 332 ? 143.290 136.916 184.837 1.00 88.74  ? 348 ASP E OD2 1 
ATOM   10671 N N   . ALA D 2 333 ? 146.829 140.075 182.323 1.00 72.97  ? 349 ALA E N   1 
ATOM   10672 C CA  . ALA D 2 333 ? 147.065 140.058 180.889 1.00 69.42  ? 349 ALA E CA  1 
ATOM   10673 C C   . ALA D 2 333 ? 148.506 139.671 180.599 1.00 66.31  ? 349 ALA E C   1 
ATOM   10674 O O   . ALA D 2 333 ? 149.397 139.856 181.430 1.00 69.99  ? 349 ALA E O   1 
ATOM   10675 C CB  . ALA D 2 333 ? 146.760 141.420 180.254 1.00 67.76  ? 349 ALA E CB  1 
ATOM   10676 N N   . ILE D 2 334 ? 148.720 139.121 179.408 1.00 63.88  ? 350 ILE E N   1 
ATOM   10677 C CA  . ILE D 2 334 ? 150.048 138.794 178.902 1.00 57.12  ? 350 ILE E CA  1 
ATOM   10678 C C   . ILE D 2 334 ? 150.252 139.585 177.620 1.00 56.48  ? 350 ILE E C   1 
ATOM   10679 O O   . ILE D 2 334 ? 149.480 139.438 176.666 1.00 61.98  ? 350 ILE E O   1 
ATOM   10680 C CB  . ILE D 2 334 ? 150.212 137.288 178.652 1.00 56.43  ? 350 ILE E CB  1 
ATOM   10681 C CG1 . ILE D 2 334 ? 150.360 136.541 179.976 1.00 59.89  ? 350 ILE E CG1 1 
ATOM   10682 C CG2 . ILE D 2 334 ? 151.407 137.022 177.756 1.00 54.43  ? 350 ILE E CG2 1 
ATOM   10683 C CD1 . ILE D 2 334 ? 150.574 135.061 179.813 1.00 67.83  ? 350 ILE E CD1 1 
ATOM   10684 N N   . TYR D 2 335 ? 151.285 140.420 177.596 1.00 54.15  ? 351 TYR E N   1 
ATOM   10685 C CA  . TYR D 2 335 ? 151.552 141.303 176.470 1.00 54.57  ? 351 TYR E CA  1 
ATOM   10686 C C   . TYR D 2 335 ? 152.602 140.684 175.558 1.00 53.87  ? 351 TYR E C   1 
ATOM   10687 O O   . TYR D 2 335 ? 153.639 140.209 176.031 1.00 55.96  ? 351 TYR E O   1 
ATOM   10688 C CB  . TYR D 2 335 ? 152.024 142.674 176.953 1.00 52.34  ? 351 TYR E CB  1 
ATOM   10689 C CG  . TYR D 2 335 ? 150.905 143.611 177.336 1.00 57.72  ? 351 TYR E CG  1 
ATOM   10690 C CD1 . TYR D 2 335 ? 150.104 143.355 178.440 1.00 57.71  ? 351 TYR E CD1 1 
ATOM   10691 C CD2 . TYR D 2 335 ? 150.650 144.755 176.594 1.00 57.00  ? 351 TYR E CD2 1 
ATOM   10692 C CE1 . TYR D 2 335 ? 149.080 144.213 178.794 1.00 56.81  ? 351 TYR E CE1 1 
ATOM   10693 C CE2 . TYR D 2 335 ? 149.630 145.616 176.940 1.00 58.84  ? 351 TYR E CE2 1 
ATOM   10694 C CZ  . TYR D 2 335 ? 148.849 145.341 178.040 1.00 60.14  ? 351 TYR E CZ  1 
ATOM   10695 O OH  . TYR D 2 335 ? 147.833 146.200 178.383 1.00 65.55  ? 351 TYR E OH  1 
ATOM   10696 N N   . SER D 2 336 ? 152.330 140.693 174.257 1.00 53.81  ? 352 SER E N   1 
ATOM   10697 C CA  . SER D 2 336 ? 153.275 140.243 173.239 1.00 51.08  ? 352 SER E CA  1 
ATOM   10698 C C   . SER D 2 336 ? 153.715 141.471 172.449 1.00 49.90  ? 352 SER E C   1 
ATOM   10699 O O   . SER D 2 336 ? 152.982 141.960 171.587 1.00 51.73  ? 352 SER E O   1 
ATOM   10700 C CB  . SER D 2 336 ? 152.648 139.186 172.338 1.00 55.81  ? 352 SER E CB  1 
ATOM   10701 O OG  . SER D 2 336 ? 153.438 138.974 171.183 1.00 61.57  ? 352 SER E OG  1 
ATOM   10702 N N   . LEU D 2 337 ? 154.914 141.963 172.743 1.00 47.99  ? 353 LEU E N   1 
ATOM   10703 C CA  . LEU D 2 337 ? 155.413 143.209 172.184 1.00 47.91  ? 353 LEU E CA  1 
ATOM   10704 C C   . LEU D 2 337 ? 156.540 142.945 171.195 1.00 46.82  ? 353 LEU E C   1 
ATOM   10705 O O   . LEU D 2 337 ? 157.329 142.011 171.360 1.00 49.42  ? 353 LEU E O   1 
ATOM   10706 C CB  . LEU D 2 337 ? 155.914 144.146 173.287 1.00 45.73  ? 353 LEU E CB  1 
ATOM   10707 C CG  . LEU D 2 337 ? 155.039 144.300 174.531 1.00 46.96  ? 353 LEU E CG  1 
ATOM   10708 C CD1 . LEU D 2 337 ? 155.537 143.413 175.657 1.00 44.86  ? 353 LEU E CD1 1 
ATOM   10709 C CD2 . LEU D 2 337 ? 155.002 145.752 174.967 1.00 47.06  ? 353 LEU E CD2 1 
ATOM   10710 N N   . GLY D 2 338 ? 156.604 143.783 170.164 1.00 49.15  ? 354 GLY E N   1 
ATOM   10711 C CA  . GLY D 2 338 ? 157.663 143.722 169.179 1.00 47.70  ? 354 GLY E CA  1 
ATOM   10712 C C   . GLY D 2 338 ? 157.655 142.416 168.409 1.00 48.80  ? 354 GLY E C   1 
ATOM   10713 O O   . GLY D 2 338 ? 156.615 141.786 168.195 1.00 55.71  ? 354 GLY E O   1 
ATOM   10714 N N   . GLY D 2 339 ? 158.840 142.001 167.989 1.00 49.21  ? 355 GLY E N   1 
ATOM   10715 C CA  . GLY D 2 339 ? 159.020 140.762 167.260 1.00 51.90  ? 355 GLY E CA  1 
ATOM   10716 C C   . GLY D 2 339 ? 159.532 141.008 165.851 1.00 61.27  ? 355 GLY E C   1 
ATOM   10717 O O   . GLY D 2 339 ? 159.741 142.141 165.414 1.00 59.44  ? 355 GLY E O   1 
ATOM   10718 N N   . LYS D 2 340 ? 159.738 139.901 165.144 1.00 67.82  ? 356 LYS E N   1 
ATOM   10719 C CA  . LYS D 2 340 ? 160.177 139.920 163.756 1.00 70.28  ? 356 LYS E CA  1 
ATOM   10720 C C   . LYS D 2 340 ? 159.271 139.001 162.953 1.00 76.20  ? 356 LYS E C   1 
ATOM   10721 O O   . LYS D 2 340 ? 159.054 137.847 163.338 1.00 75.04  ? 356 LYS E O   1 
ATOM   10722 C CB  . LYS D 2 340 ? 161.642 139.486 163.636 1.00 70.86  ? 356 LYS E CB  1 
ATOM   10723 C CG  . LYS D 2 340 ? 161.975 138.719 162.371 1.00 75.32  ? 356 LYS E CG  1 
ATOM   10724 C CD  . LYS D 2 340 ? 163.425 138.268 162.369 1.00 73.58  ? 356 LYS E CD  1 
ATOM   10725 C CE  . LYS D 2 340 ? 164.369 139.440 162.578 1.00 73.59  ? 356 LYS E CE  1 
ATOM   10726 N NZ  . LYS D 2 340 ? 165.734 138.992 162.966 1.00 67.94  ? 356 LYS E NZ  1 
ATOM   10727 N N   . THR D 2 341 ? 158.739 139.511 161.848 1.00 79.41  ? 357 THR E N   1 
ATOM   10728 C CA  . THR D 2 341 ? 157.805 138.753 161.032 1.00 81.53  ? 357 THR E CA  1 
ATOM   10729 C C   . THR D 2 341 ? 158.551 137.884 160.021 1.00 84.25  ? 357 THR E C   1 
ATOM   10730 O O   . THR D 2 341 ? 159.756 138.024 159.805 1.00 84.59  ? 357 THR E O   1 
ATOM   10731 C CB  . THR D 2 341 ? 156.829 139.691 160.321 1.00 83.13  ? 357 THR E CB  1 
ATOM   10732 O OG1 . THR D 2 341 ? 155.646 138.968 159.961 1.00 85.73  ? 357 THR E OG1 1 
ATOM   10733 C CG2 . THR D 2 341 ? 157.460 140.268 159.070 1.00 81.66  ? 357 THR E CG2 1 
ATOM   10734 N N   . LEU D 2 342 ? 157.808 136.968 159.396 1.00 87.69  ? 358 LEU E N   1 
ATOM   10735 C CA  . LEU D 2 342 ? 158.408 136.016 158.468 1.00 89.46  ? 358 LEU E CA  1 
ATOM   10736 C C   . LEU D 2 342 ? 158.945 136.681 157.207 1.00 92.09  ? 358 LEU E C   1 
ATOM   10737 O O   . LEU D 2 342 ? 159.729 136.060 156.482 1.00 92.65  ? 358 LEU E O   1 
ATOM   10738 C CB  . LEU D 2 342 ? 157.388 134.938 158.096 1.00 88.62  ? 358 LEU E CB  1 
ATOM   10739 C CG  . LEU D 2 342 ? 156.841 134.116 159.265 1.00 97.08  ? 358 LEU E CG  1 
ATOM   10740 C CD1 . LEU D 2 342 ? 155.438 133.614 158.965 1.00 105.96 ? 358 LEU E CD1 1 
ATOM   10741 C CD2 . LEU D 2 342 ? 157.770 132.956 159.587 1.00 98.19  ? 358 LEU E CD2 1 
ATOM   10742 N N   . GLN D 2 343 ? 158.549 137.923 156.930 1.00 92.01  ? 359 GLN E N   1 
ATOM   10743 C CA  . GLN D 2 343 ? 159.050 138.668 155.783 1.00 88.56  ? 359 GLN E CA  1 
ATOM   10744 C C   . GLN D 2 343 ? 160.372 139.370 156.067 1.00 90.05  ? 359 GLN E C   1 
ATOM   10745 O O   . GLN D 2 343 ? 160.753 140.271 155.311 1.00 88.60  ? 359 GLN E O   1 
ATOM   10746 C CB  . GLN D 2 343 ? 158.006 139.689 155.321 1.00 86.19  ? 359 GLN E CB  1 
ATOM   10747 C CG  . GLN D 2 343 ? 156.568 139.195 155.394 1.00 89.12  ? 359 GLN E CG  1 
ATOM   10748 C CD  . GLN D 2 343 ? 156.348 137.909 154.622 1.00 90.53  ? 359 GLN E CD  1 
ATOM   10749 O OE1 . GLN D 2 343 ? 156.540 136.813 155.149 1.00 89.74  ? 359 GLN E OE1 1 
ATOM   10750 N NE2 . GLN D 2 343 ? 155.943 138.037 153.365 1.00 89.81  ? 359 GLN E NE2 1 
ATOM   10751 N N   . ASP D 2 344 ? 161.065 138.973 157.137 1.00 89.85  ? 360 ASP E N   1 
ATOM   10752 C CA  . ASP D 2 344 ? 162.358 139.547 157.514 1.00 88.17  ? 360 ASP E CA  1 
ATOM   10753 C C   . ASP D 2 344 ? 162.268 141.057 157.722 1.00 87.77  ? 360 ASP E C   1 
ATOM   10754 O O   . ASP D 2 344 ? 163.178 141.806 157.362 1.00 89.90  ? 360 ASP E O   1 
ATOM   10755 C CB  . ASP D 2 344 ? 163.437 139.203 156.486 1.00 88.78  ? 360 ASP E CB  1 
ATOM   10756 C CG  . ASP D 2 344 ? 164.324 138.059 156.934 1.00 95.85  ? 360 ASP E CG  1 
ATOM   10757 O OD1 . ASP D 2 344 ? 164.052 137.481 158.007 1.00 94.68  ? 360 ASP E OD1 1 
ATOM   10758 O OD2 . ASP D 2 344 ? 165.294 137.740 156.214 1.00 92.30  ? 360 ASP E OD2 1 
ATOM   10759 N N   . THR D 2 345 ? 161.162 141.511 158.307 1.00 85.71  ? 361 THR E N   1 
ATOM   10760 C CA  . THR D 2 345 ? 160.997 142.905 158.690 1.00 80.14  ? 361 THR E CA  1 
ATOM   10761 C C   . THR D 2 345 ? 160.594 142.974 160.154 1.00 79.29  ? 361 THR E C   1 
ATOM   10762 O O   . THR D 2 345 ? 159.755 142.194 160.614 1.00 79.27  ? 361 THR E O   1 
ATOM   10763 C CB  . THR D 2 345 ? 159.946 143.621 157.826 1.00 83.13  ? 361 THR E CB  1 
ATOM   10764 O OG1 . THR D 2 345 ? 158.693 142.936 157.918 1.00 89.93  ? 361 THR E OG1 1 
ATOM   10765 C CG2 . THR D 2 345 ? 160.386 143.664 156.374 1.00 81.25  ? 361 THR E CG2 1 
ATOM   10766 N N   . LEU D 2 346 ? 161.201 143.906 160.883 1.00 77.52  ? 362 LEU E N   1 
ATOM   10767 C CA  . LEU D 2 346 ? 160.891 144.070 162.295 1.00 72.55  ? 362 LEU E CA  1 
ATOM   10768 C C   . LEU D 2 346 ? 159.480 144.619 162.472 1.00 69.91  ? 362 LEU E C   1 
ATOM   10769 O O   . LEU D 2 346 ? 158.965 145.358 161.629 1.00 70.01  ? 362 LEU E O   1 
ATOM   10770 C CB  . LEU D 2 346 ? 161.910 144.995 162.959 1.00 62.04  ? 362 LEU E CB  1 
ATOM   10771 C CG  . LEU D 2 346 ? 163.334 144.443 163.039 1.00 56.19  ? 362 LEU E CG  1 
ATOM   10772 C CD1 . LEU D 2 346 ? 164.235 145.390 163.800 1.00 54.01  ? 362 LEU E CD1 1 
ATOM   10773 C CD2 . LEU D 2 346 ? 163.339 143.072 163.683 1.00 58.41  ? 362 LEU E CD2 1 
ATOM   10774 N N   . SER D 2 347 ? 158.856 144.248 163.585 1.00 65.25  ? 363 SER E N   1 
ATOM   10775 C CA  . SER D 2 347 ? 157.469 144.588 163.863 1.00 63.17  ? 363 SER E CA  1 
ATOM   10776 C C   . SER D 2 347 ? 157.379 145.425 165.129 1.00 61.22  ? 363 SER E C   1 
ATOM   10777 O O   . SER D 2 347 ? 158.154 145.231 166.071 1.00 64.46  ? 363 SER E O   1 
ATOM   10778 C CB  . SER D 2 347 ? 156.616 143.324 164.009 1.00 59.26  ? 363 SER E CB  1 
ATOM   10779 O OG  . SER D 2 347 ? 155.542 143.534 164.906 1.00 57.31  ? 363 SER E OG  1 
ATOM   10780 N N   . ASN D 2 348 ? 156.434 146.364 165.145 1.00 59.24  ? 364 ASN E N   1 
ATOM   10781 C CA  . ASN D 2 348 ? 156.156 147.180 166.320 1.00 60.38  ? 364 ASN E CA  1 
ATOM   10782 C C   . ASN D 2 348 ? 154.724 146.984 166.804 1.00 59.42  ? 364 ASN E C   1 
ATOM   10783 O O   . ASN D 2 348 ? 154.094 147.919 167.295 1.00 60.84  ? 364 ASN E O   1 
ATOM   10784 C CB  . ASN D 2 348 ? 156.434 148.658 166.041 1.00 59.32  ? 364 ASN E CB  1 
ATOM   10785 C CG  . ASN D 2 348 ? 155.638 149.196 164.869 1.00 64.27  ? 364 ASN E CG  1 
ATOM   10786 O OD1 . ASN D 2 348 ? 154.777 148.513 164.317 1.00 64.61  ? 364 ASN E OD1 1 
ATOM   10787 N ND2 . ASN D 2 348 ? 155.923 150.434 164.485 1.00 65.82  ? 364 ASN E ND2 1 
ATOM   10788 N N   . ALA D 2 349 ? 154.201 145.772 166.669 1.00 59.17  ? 365 ALA E N   1 
ATOM   10789 C CA  . ALA D 2 349 ? 152.840 145.470 167.083 1.00 60.43  ? 365 ALA E CA  1 
ATOM   10790 C C   . ALA D 2 349 ? 152.817 145.003 168.531 1.00 60.80  ? 365 ALA E C   1 
ATOM   10791 O O   . ALA D 2 349 ? 153.631 144.172 168.942 1.00 59.63  ? 365 ALA E O   1 
ATOM   10792 C CB  . ALA D 2 349 ? 152.226 144.401 166.178 1.00 61.08  ? 365 ALA E CB  1 
ATOM   10793 N N   . VAL D 2 350 ? 151.877 145.546 169.301 1.00 64.74  ? 366 VAL E N   1 
ATOM   10794 C CA  . VAL D 2 350 ? 151.676 145.174 170.696 1.00 58.87  ? 366 VAL E CA  1 
ATOM   10795 C C   . VAL D 2 350 ? 150.269 144.618 170.842 1.00 60.65  ? 366 VAL E C   1 
ATOM   10796 O O   . VAL D 2 350 ? 149.295 145.270 170.449 1.00 63.43  ? 366 VAL E O   1 
ATOM   10797 C CB  . VAL D 2 350 ? 151.885 146.369 171.642 1.00 57.74  ? 366 VAL E CB  1 
ATOM   10798 C CG1 . VAL D 2 350 ? 151.766 145.924 173.088 1.00 56.78  ? 366 VAL E CG1 1 
ATOM   10799 C CG2 . VAL D 2 350 ? 153.228 147.016 171.387 1.00 57.49  ? 366 VAL E CG2 1 
ATOM   10800 N N   . ILE D 2 351 ? 150.165 143.413 171.401 1.00 59.41  ? 367 ILE E N   1 
ATOM   10801 C CA  . ILE D 2 351 ? 148.886 142.781 171.685 1.00 61.51  ? 367 ILE E CA  1 
ATOM   10802 C C   . ILE D 2 351 ? 148.933 142.233 173.103 1.00 59.73  ? 367 ILE E C   1 
ATOM   10803 O O   . ILE D 2 351 ? 150.001 141.953 173.650 1.00 63.20  ? 367 ILE E O   1 
ATOM   10804 C CB  . ILE D 2 351 ? 148.548 141.658 170.680 1.00 62.62  ? 367 ILE E CB  1 
ATOM   10805 C CG1 . ILE D 2 351 ? 149.601 140.553 170.738 1.00 60.18  ? 367 ILE E CG1 1 
ATOM   10806 C CG2 . ILE D 2 351 ? 148.446 142.213 169.270 1.00 65.40  ? 367 ILE E CG2 1 
ATOM   10807 C CD1 . ILE D 2 351 ? 149.430 139.491 169.677 1.00 63.57  ? 367 ILE E CD1 1 
ATOM   10808 N N   . TYR D 2 352 ? 147.755 142.084 173.704 1.00 58.84  ? 368 TYR E N   1 
ATOM   10809 C CA  . TYR D 2 352 ? 147.646 141.540 175.049 1.00 60.88  ? 368 TYR E CA  1 
ATOM   10810 C C   . TYR D 2 352 ? 146.570 140.466 175.085 1.00 63.69  ? 368 TYR E C   1 
ATOM   10811 O O   . TYR D 2 352 ? 145.671 140.433 174.242 1.00 67.69  ? 368 TYR E O   1 
ATOM   10812 C CB  . TYR D 2 352 ? 147.347 142.633 176.092 1.00 64.70  ? 368 TYR E CB  1 
ATOM   10813 C CG  . TYR D 2 352 ? 145.987 143.284 175.982 1.00 66.58  ? 368 TYR E CG  1 
ATOM   10814 C CD1 . TYR D 2 352 ? 144.887 142.759 176.646 1.00 69.05  ? 368 TYR E CD1 1 
ATOM   10815 C CD2 . TYR D 2 352 ? 145.809 144.436 175.232 1.00 65.05  ? 368 TYR E CD2 1 
ATOM   10816 C CE1 . TYR D 2 352 ? 143.647 143.354 176.551 1.00 72.49  ? 368 TYR E CE1 1 
ATOM   10817 C CE2 . TYR D 2 352 ? 144.574 145.038 175.132 1.00 68.09  ? 368 TYR E CE2 1 
ATOM   10818 C CZ  . TYR D 2 352 ? 143.496 144.493 175.793 1.00 73.13  ? 368 TYR E CZ  1 
ATOM   10819 O OH  . TYR D 2 352 ? 142.261 145.091 175.697 1.00 77.81  ? 368 TYR E OH  1 
ATOM   10820 N N   . TYR D 2 353 ? 146.676 139.586 176.077 1.00 64.79  ? 369 TYR E N   1 
ATOM   10821 C CA  . TYR D 2 353 ? 145.816 138.413 176.196 1.00 68.05  ? 369 TYR E CA  1 
ATOM   10822 C C   . TYR D 2 353 ? 145.261 138.360 177.611 1.00 73.97  ? 369 TYR E C   1 
ATOM   10823 O O   . TYR D 2 353 ? 146.011 138.138 178.566 1.00 75.01  ? 369 TYR E O   1 
ATOM   10824 C CB  . TYR D 2 353 ? 146.594 137.141 175.860 1.00 67.88  ? 369 TYR E CB  1 
ATOM   10825 C CG  . TYR D 2 353 ? 146.022 135.867 176.437 1.00 72.72  ? 369 TYR E CG  1 
ATOM   10826 C CD1 . TYR D 2 353 ? 144.945 135.233 175.836 1.00 79.37  ? 369 TYR E CD1 1 
ATOM   10827 C CD2 . TYR D 2 353 ? 146.575 135.285 177.569 1.00 73.76  ? 369 TYR E CD2 1 
ATOM   10828 C CE1 . TYR D 2 353 ? 144.425 134.065 176.353 1.00 82.57  ? 369 TYR E CE1 1 
ATOM   10829 C CE2 . TYR D 2 353 ? 146.061 134.118 178.094 1.00 80.62  ? 369 TYR E CE2 1 
ATOM   10830 C CZ  . TYR D 2 353 ? 144.986 133.512 177.481 1.00 83.62  ? 369 TYR E CZ  1 
ATOM   10831 O OH  . TYR D 2 353 ? 144.469 132.348 177.998 1.00 85.76  ? 369 TYR E OH  1 
ATOM   10832 N N   . ARG D 2 354 ? 143.952 138.559 177.747 1.00 80.32  ? 370 ARG E N   1 
ATOM   10833 C CA  . ARG D 2 354 ? 143.306 138.485 179.049 1.00 78.90  ? 370 ARG E CA  1 
ATOM   10834 C C   . ARG D 2 354 ? 143.023 137.030 179.397 1.00 79.64  ? 370 ARG E C   1 
ATOM   10835 O O   . ARG D 2 354 ? 142.412 136.302 178.609 1.00 81.37  ? 370 ARG E O   1 
ATOM   10836 C CB  . ARG D 2 354 ? 142.011 139.294 179.049 1.00 82.40  ? 370 ARG E CB  1 
ATOM   10837 C CG  . ARG D 2 354 ? 142.119 140.638 178.351 1.00 82.85  ? 370 ARG E CG  1 
ATOM   10838 C CD  . ARG D 2 354 ? 141.218 141.675 179.000 1.00 85.27  ? 370 ARG E CD  1 
ATOM   10839 N NE  . ARG D 2 354 ? 141.267 141.614 180.456 1.00 87.87  ? 370 ARG E NE  1 
ATOM   10840 C CZ  . ARG D 2 354 ? 141.922 142.478 181.220 1.00 87.15  ? 370 ARG E CZ  1 
ATOM   10841 N NH1 . ARG D 2 354 ? 142.602 143.485 180.697 1.00 83.50  ? 370 ARG E NH1 1 
ATOM   10842 N NH2 . ARG D 2 354 ? 141.893 142.328 182.541 1.00 84.25  ? 370 ARG E NH2 1 
ATOM   10843 N N   . VAL D 2 355 ? 143.476 136.606 180.578 1.00 81.37  ? 371 VAL E N   1 
ATOM   10844 C CA  . VAL D 2 355 ? 143.348 135.203 180.960 1.00 86.87  ? 371 VAL E CA  1 
ATOM   10845 C C   . VAL D 2 355 ? 141.883 134.822 181.137 1.00 90.70  ? 371 VAL E C   1 
ATOM   10846 O O   . VAL D 2 355 ? 141.453 133.743 180.712 1.00 92.80  ? 371 VAL E O   1 
ATOM   10847 C CB  . VAL D 2 355 ? 144.168 134.919 182.230 1.00 86.88  ? 371 VAL E CB  1 
ATOM   10848 C CG1 . VAL D 2 355 ? 144.095 133.445 182.588 1.00 84.75  ? 371 VAL E CG1 1 
ATOM   10849 C CG2 . VAL D 2 355 ? 145.611 135.352 182.033 1.00 81.14  ? 371 VAL E CG2 1 
ATOM   10850 N N   . GLY D 2 356 ? 141.094 135.692 181.770 1.00 88.44  ? 372 GLY E N   1 
ATOM   10851 C CA  . GLY D 2 356 ? 139.684 135.396 181.953 1.00 87.47  ? 372 GLY E CA  1 
ATOM   10852 C C   . GLY D 2 356 ? 138.868 135.545 180.686 1.00 87.12  ? 372 GLY E C   1 
ATOM   10853 O O   . GLY D 2 356 ? 137.897 134.811 180.480 1.00 86.91  ? 372 GLY E O   1 
ATOM   10854 N N   . ASP D 2 357 ? 139.245 136.485 179.821 1.00 85.71  ? 373 ASP E N   1 
ATOM   10855 C CA  . ASP D 2 357 ? 138.527 136.707 178.573 1.00 87.32  ? 373 ASP E CA  1 
ATOM   10856 C C   . ASP D 2 357 ? 138.957 135.753 177.469 1.00 89.72  ? 373 ASP E C   1 
ATOM   10857 O O   . ASP D 2 357 ? 138.146 135.432 176.592 1.00 91.56  ? 373 ASP E O   1 
ATOM   10858 C CB  . ASP D 2 357 ? 138.722 138.152 178.104 1.00 89.28  ? 373 ASP E CB  1 
ATOM   10859 C CG  . ASP D 2 357 ? 137.634 138.609 177.153 1.00 94.69  ? 373 ASP E CG  1 
ATOM   10860 O OD1 . ASP D 2 357 ? 136.629 137.883 177.001 1.00 98.08  ? 373 ASP E OD1 1 
ATOM   10861 O OD2 . ASP D 2 357 ? 137.786 139.695 176.555 1.00 90.63  ? 373 ASP E OD2 1 
ATOM   10862 N N   . ASN D 2 358 ? 140.210 135.293 177.498 1.00 90.43  ? 374 ASN E N   1 
ATOM   10863 C CA  . ASN D 2 358 ? 140.748 134.376 176.490 1.00 88.87  ? 374 ASN E CA  1 
ATOM   10864 C C   . ASN D 2 358 ? 140.633 134.961 175.084 1.00 88.72  ? 374 ASN E C   1 
ATOM   10865 O O   . ASN D 2 358 ? 140.329 134.254 174.122 1.00 90.48  ? 374 ASN E O   1 
ATOM   10866 C CB  . ASN D 2 358 ? 140.067 133.008 176.568 1.00 89.38  ? 374 ASN E CB  1 
ATOM   10867 C CG  . ASN D 2 358 ? 141.001 131.873 176.210 1.00 92.35  ? 374 ASN E CG  1 
ATOM   10868 O OD1 . ASN D 2 358 ? 141.409 131.729 175.057 1.00 93.95  ? 374 ASN E OD1 1 
ATOM   10869 N ND2 . ASN D 2 358 ? 141.343 131.055 177.198 1.00 91.72  ? 374 ASN E ND2 1 
ATOM   10870 N N   . VAL D 2 359 ? 140.874 136.265 174.964 1.00 86.48  ? 375 VAL E N   1 
ATOM   10871 C CA  . VAL D 2 359 ? 140.798 136.974 173.693 1.00 86.29  ? 375 VAL E CA  1 
ATOM   10872 C C   . VAL D 2 359 ? 142.043 137.838 173.545 1.00 82.18  ? 375 VAL E C   1 
ATOM   10873 O O   . VAL D 2 359 ? 142.424 138.547 174.483 1.00 79.10  ? 375 VAL E O   1 
ATOM   10874 C CB  . VAL D 2 359 ? 139.525 137.840 173.595 1.00 86.95  ? 375 VAL E CB  1 
ATOM   10875 C CG1 . VAL D 2 359 ? 139.495 138.604 172.279 1.00 84.59  ? 375 VAL E CG1 1 
ATOM   10876 C CG2 . VAL D 2 359 ? 138.280 136.982 173.738 1.00 86.66  ? 375 VAL E CG2 1 
ATOM   10877 N N   . TRP D 2 360 ? 142.672 137.778 172.374 1.00 78.57  ? 376 TRP E N   1 
ATOM   10878 C CA  . TRP D 2 360 ? 143.817 138.624 172.064 1.00 73.99  ? 376 TRP E CA  1 
ATOM   10879 C C   . TRP D 2 360 ? 143.329 139.939 171.469 1.00 72.47  ? 376 TRP E C   1 
ATOM   10880 O O   . TRP D 2 360 ? 142.510 139.942 170.545 1.00 76.11  ? 376 TRP E O   1 
ATOM   10881 C CB  . TRP D 2 360 ? 144.765 137.923 171.090 1.00 73.08  ? 376 TRP E CB  1 
ATOM   10882 C CG  . TRP D 2 360 ? 145.580 136.833 171.715 1.00 77.40  ? 376 TRP E CG  1 
ATOM   10883 C CD1 . TRP D 2 360 ? 145.230 135.523 171.844 1.00 78.15  ? 376 TRP E CD1 1 
ATOM   10884 C CD2 . TRP D 2 360 ? 146.884 136.958 172.296 1.00 75.92  ? 376 TRP E CD2 1 
ATOM   10885 N NE1 . TRP D 2 360 ? 146.232 134.822 172.469 1.00 76.11  ? 376 TRP E NE1 1 
ATOM   10886 C CE2 . TRP D 2 360 ? 147.259 135.681 172.757 1.00 74.90  ? 376 TRP E CE2 1 
ATOM   10887 C CE3 . TRP D 2 360 ? 147.769 138.024 172.473 1.00 69.67  ? 376 TRP E CE3 1 
ATOM   10888 C CZ2 . TRP D 2 360 ? 148.480 135.444 173.381 1.00 70.66  ? 376 TRP E CZ2 1 
ATOM   10889 C CZ3 . TRP D 2 360 ? 148.979 137.786 173.091 1.00 64.94  ? 376 TRP E CZ3 1 
ATOM   10890 C CH2 . TRP D 2 360 ? 149.323 136.507 173.539 1.00 67.26  ? 376 TRP E CH2 1 
ATOM   10891 N N   . THR D 2 361 ? 143.833 141.051 171.998 1.00 68.84  ? 377 THR E N   1 
ATOM   10892 C CA  . THR D 2 361 ? 143.403 142.380 171.586 1.00 67.38  ? 377 THR E CA  1 
ATOM   10893 C C   . THR D 2 361 ? 144.615 143.210 171.197 1.00 66.34  ? 377 THR E C   1 
ATOM   10894 O O   . THR D 2 361 ? 145.625 143.208 171.907 1.00 70.06  ? 377 THR E O   1 
ATOM   10895 C CB  . THR D 2 361 ? 142.626 143.079 172.706 1.00 70.03  ? 377 THR E CB  1 
ATOM   10896 O OG1 . THR D 2 361 ? 141.602 142.205 173.196 1.00 74.03  ? 377 THR E OG1 1 
ATOM   10897 C CG2 . THR D 2 361 ? 141.993 144.365 172.199 1.00 70.05  ? 377 THR E CG2 1 
ATOM   10898 N N   . GLU D 2 362 ? 144.513 143.918 170.076 1.00 65.38  ? 378 GLU E N   1 
ATOM   10899 C CA  . GLU D 2 362 ? 145.596 144.782 169.639 1.00 65.98  ? 378 GLU E CA  1 
ATOM   10900 C C   . GLU D 2 362 ? 145.648 146.051 170.487 1.00 67.23  ? 378 GLU E C   1 
ATOM   10901 O O   . GLU D 2 362 ? 144.665 146.455 171.114 1.00 70.42  ? 378 GLU E O   1 
ATOM   10902 C CB  . GLU D 2 362 ? 145.436 145.140 168.162 1.00 67.28  ? 378 GLU E CB  1 
ATOM   10903 C CG  . GLU D 2 362 ? 145.965 144.080 167.210 1.00 71.82  ? 378 GLU E CG  1 
ATOM   10904 C CD  . GLU D 2 362 ? 147.218 144.525 166.481 1.00 75.68  ? 378 GLU E CD  1 
ATOM   10905 O OE1 . GLU D 2 362 ? 147.731 145.621 166.793 1.00 75.42  ? 378 GLU E OE1 1 
ATOM   10906 O OE2 . GLU D 2 362 ? 147.691 143.779 165.598 1.00 73.99  ? 378 GLU E OE2 1 
ATOM   10907 N N   . THR D 2 363 ? 146.822 146.680 170.503 1.00 65.91  ? 379 THR E N   1 
ATOM   10908 C CA  . THR D 2 363 ? 147.058 147.883 171.288 1.00 63.30  ? 379 THR E CA  1 
ATOM   10909 C C   . THR D 2 363 ? 147.966 148.801 170.472 1.00 66.36  ? 379 THR E C   1 
ATOM   10910 O O   . THR D 2 363 ? 148.386 148.459 169.362 1.00 70.94  ? 379 THR E O   1 
ATOM   10911 C CB  . THR D 2 363 ? 147.656 147.524 172.656 1.00 66.38  ? 379 THR E CB  1 
ATOM   10912 O OG1 . THR D 2 363 ? 146.930 146.421 173.208 1.00 66.88  ? 379 THR E OG1 1 
ATOM   10913 C CG2 . THR D 2 363 ? 147.523 148.682 173.636 1.00 69.25  ? 379 THR E CG2 1 
ATOM   10914 N N   . THR D 2 364 ? 148.266 149.977 171.019 1.00 64.54  ? 380 THR E N   1 
ATOM   10915 C CA  . THR D 2 364 ? 149.073 150.958 170.309 1.00 67.83  ? 380 THR E CA  1 
ATOM   10916 C C   . THR D 2 364 ? 150.473 150.418 170.034 1.00 69.30  ? 380 THR E C   1 
ATOM   10917 O O   . THR D 2 364 ? 151.020 149.620 170.799 1.00 68.23  ? 380 THR E O   1 
ATOM   10918 C CB  . THR D 2 364 ? 149.163 152.256 171.112 1.00 69.42  ? 380 THR E CB  1 
ATOM   10919 O OG1 . THR D 2 364 ? 150.239 153.059 170.610 1.00 71.42  ? 380 THR E OG1 1 
ATOM   10920 C CG2 . THR D 2 364 ? 149.402 151.959 172.579 1.00 66.59  ? 380 THR E CG2 1 
ATOM   10921 N N   . GLN D 2 365 ? 151.047 150.861 168.920 1.00 69.58  ? 381 GLN E N   1 
ATOM   10922 C CA  . GLN D 2 365 ? 152.348 150.381 168.489 1.00 65.22  ? 381 GLN E CA  1 
ATOM   10923 C C   . GLN D 2 365 ? 153.469 151.016 169.306 1.00 61.84  ? 381 GLN E C   1 
ATOM   10924 O O   . GLN D 2 365 ? 153.283 152.019 170.000 1.00 62.28  ? 381 GLN E O   1 
ATOM   10925 C CB  . GLN D 2 365 ? 152.573 150.678 167.006 1.00 68.18  ? 381 GLN E CB  1 
ATOM   10926 C CG  . GLN D 2 365 ? 151.312 150.910 166.203 1.00 68.02  ? 381 GLN E CG  1 
ATOM   10927 C CD  . GLN D 2 365 ? 151.614 151.253 164.760 1.00 71.94  ? 381 GLN E CD  1 
ATOM   10928 O OE1 . GLN D 2 365 ? 152.491 152.068 164.477 1.00 73.23  ? 381 GLN E OE1 1 
ATOM   10929 N NE2 . GLN D 2 365 ? 150.891 150.630 163.837 1.00 75.98  ? 381 GLN E NE2 1 
ATOM   10930 N N   . LEU D 2 366 ? 154.648 150.410 169.211 1.00 59.11  ? 382 LEU E N   1 
ATOM   10931 C CA  . LEU D 2 366 ? 155.846 150.968 169.810 1.00 58.83  ? 382 LEU E CA  1 
ATOM   10932 C C   . LEU D 2 366 ? 156.408 152.083 168.935 1.00 59.24  ? 382 LEU E C   1 
ATOM   10933 O O   . LEU D 2 366 ? 156.094 152.196 167.747 1.00 60.93  ? 382 LEU E O   1 
ATOM   10934 C CB  . LEU D 2 366 ? 156.903 149.882 170.016 1.00 54.79  ? 382 LEU E CB  1 
ATOM   10935 C CG  . LEU D 2 366 ? 156.434 148.558 170.615 1.00 51.90  ? 382 LEU E CG  1 
ATOM   10936 C CD1 . LEU D 2 366 ? 157.350 147.426 170.189 1.00 52.13  ? 382 LEU E CD1 1 
ATOM   10937 C CD2 . LEU D 2 366 ? 156.374 148.658 172.129 1.00 51.07  ? 382 LEU E CD2 1 
ATOM   10938 N N   . GLU D 2 367 ? 157.252 152.918 169.543 1.00 57.23  ? 383 GLU E N   1 
ATOM   10939 C CA  . GLU D 2 367 ? 157.881 153.998 168.790 1.00 59.72  ? 383 GLU E CA  1 
ATOM   10940 C C   . GLU D 2 367 ? 158.877 153.457 167.772 1.00 57.50  ? 383 GLU E C   1 
ATOM   10941 O O   . GLU D 2 367 ? 158.994 153.995 166.665 1.00 60.37  ? 383 GLU E O   1 
ATOM   10942 C CB  . GLU D 2 367 ? 158.560 154.978 169.744 1.00 63.90  ? 383 GLU E CB  1 
ATOM   10943 C CG  . GLU D 2 367 ? 157.631 155.553 170.797 1.00 65.45  ? 383 GLU E CG  1 
ATOM   10944 C CD  . GLU D 2 367 ? 157.601 157.067 170.782 1.00 72.37  ? 383 GLU E CD  1 
ATOM   10945 O OE1 . GLU D 2 367 ? 158.682 157.686 170.867 1.00 69.41  ? 383 GLU E OE1 1 
ATOM   10946 O OE2 . GLU D 2 367 ? 156.495 157.640 170.684 1.00 77.74  ? 383 GLU E OE2 1 
ATOM   10947 N N   . VAL D 2 368 ? 159.609 152.400 168.127 1.00 53.95  ? 384 VAL E N   1 
ATOM   10948 C CA  . VAL D 2 368 ? 160.529 151.741 167.212 1.00 53.12  ? 384 VAL E CA  1 
ATOM   10949 C C   . VAL D 2 368 ? 160.203 150.254 167.186 1.00 55.86  ? 384 VAL E C   1 
ATOM   10950 O O   . VAL D 2 368 ? 159.576 149.713 168.099 1.00 57.56  ? 384 VAL E O   1 
ATOM   10951 C CB  . VAL D 2 368 ? 162.013 151.962 167.590 1.00 50.06  ? 384 VAL E CB  1 
ATOM   10952 C CG1 . VAL D 2 368 ? 162.258 153.406 168.000 1.00 53.43  ? 384 VAL E CG1 1 
ATOM   10953 C CG2 . VAL D 2 368 ? 162.434 151.011 168.692 1.00 52.53  ? 384 VAL E CG2 1 
ATOM   10954 N N   . ALA D 2 369 ? 160.633 149.597 166.114 1.00 55.97  ? 385 ALA E N   1 
ATOM   10955 C CA  . ALA D 2 369 ? 160.403 148.172 165.920 1.00 54.91  ? 385 ALA E CA  1 
ATOM   10956 C C   . ALA D 2 369 ? 161.655 147.411 166.332 1.00 54.93  ? 385 ALA E C   1 
ATOM   10957 O O   . ALA D 2 369 ? 162.739 147.652 165.789 1.00 56.51  ? 385 ALA E O   1 
ATOM   10958 C CB  . ALA D 2 369 ? 160.041 147.871 164.467 1.00 59.51  ? 385 ALA E CB  1 
ATOM   10959 N N   . VAL D 2 370 ? 161.505 146.497 167.292 1.00 53.18  ? 386 VAL E N   1 
ATOM   10960 C CA  . VAL D 2 370 ? 162.618 145.722 167.823 1.00 51.28  ? 386 VAL E CA  1 
ATOM   10961 C C   . VAL D 2 370 ? 162.200 144.265 167.946 1.00 49.34  ? 386 VAL E C   1 
ATOM   10962 O O   . VAL D 2 370 ? 161.014 143.934 167.987 1.00 51.96  ? 386 VAL E O   1 
ATOM   10963 C CB  . VAL D 2 370 ? 163.099 146.249 169.194 1.00 46.99  ? 386 VAL E CB  1 
ATOM   10964 C CG1 . VAL D 2 370 ? 163.819 147.576 169.036 1.00 44.64  ? 386 VAL E CG1 1 
ATOM   10965 C CG2 . VAL D 2 370 ? 161.924 146.382 170.147 1.00 49.41  ? 386 VAL E CG2 1 
ATOM   10966 N N   . SER D 2 371 ? 163.201 143.390 168.001 1.00 47.29  ? 387 SER E N   1 
ATOM   10967 C CA  . SER D 2 371 ? 162.988 141.973 168.249 1.00 49.50  ? 387 SER E CA  1 
ATOM   10968 C C   . SER D 2 371 ? 164.086 141.464 169.168 1.00 47.94  ? 387 SER E C   1 
ATOM   10969 O O   . SER D 2 371 ? 165.218 141.951 169.136 1.00 48.11  ? 387 SER E O   1 
ATOM   10970 C CB  . SER D 2 371 ? 162.965 141.164 166.947 1.00 53.91  ? 387 SER E CB  1 
ATOM   10971 O OG  . SER D 2 371 ? 164.268 141.009 166.419 1.00 54.18  ? 387 SER E OG  1 
ATOM   10972 N N   . GLY D 2 372 ? 163.741 140.478 169.992 1.00 45.99  ? 388 GLY E N   1 
ATOM   10973 C CA  . GLY D 2 372 ? 164.681 139.950 170.957 1.00 42.22  ? 388 GLY E CA  1 
ATOM   10974 C C   . GLY D 2 372 ? 164.924 140.831 172.158 1.00 45.09  ? 388 GLY E C   1 
ATOM   10975 O O   . GLY D 2 372 ? 165.884 140.591 172.898 1.00 45.56  ? 388 GLY E O   1 
ATOM   10976 N N   . ALA D 2 373 ? 164.091 141.845 172.375 1.00 43.41  ? 389 ALA E N   1 
ATOM   10977 C CA  . ALA D 2 373 ? 164.287 142.754 173.493 1.00 35.85  ? 389 ALA E CA  1 
ATOM   10978 C C   . ALA D 2 373 ? 163.826 142.114 174.795 1.00 39.65  ? 389 ALA E C   1 
ATOM   10979 O O   . ALA D 2 373 ? 162.811 141.415 174.838 1.00 45.59  ? 389 ALA E O   1 
ATOM   10980 C CB  . ALA D 2 373 ? 163.531 144.059 173.252 1.00 30.96  ? 389 ALA E CB  1 
ATOM   10981 N N   . ALA D 2 374 ? 164.584 142.353 175.862 1.00 38.63  ? 390 ALA E N   1 
ATOM   10982 C CA  . ALA D 2 374 ? 164.197 141.868 177.178 1.00 31.79  ? 390 ALA E CA  1 
ATOM   10983 C C   . ALA D 2 374 ? 163.021 142.674 177.712 1.00 34.83  ? 390 ALA E C   1 
ATOM   10984 O O   . ALA D 2 374 ? 162.929 143.885 177.500 1.00 37.81  ? 390 ALA E O   1 
ATOM   10985 C CB  . ALA D 2 374 ? 165.375 141.951 178.144 1.00 30.37  ? 390 ALA E CB  1 
ATOM   10986 N N   . GLY D 2 375 ? 162.120 141.998 178.406 1.00 33.17  ? 391 GLY E N   1 
ATOM   10987 C CA  . GLY D 2 375 ? 160.923 142.626 178.944 1.00 31.11  ? 391 GLY E CA  1 
ATOM   10988 C C   . GLY D 2 375 ? 160.887 142.536 180.456 1.00 32.76  ? 391 GLY E C   1 
ATOM   10989 O O   . GLY D 2 375 ? 161.303 141.532 181.034 1.00 35.65  ? 391 GLY E O   1 
ATOM   10990 N N   . ALA D 2 376 ? 160.382 143.592 181.088 1.00 36.28  ? 392 ALA E N   1 
ATOM   10991 C CA  . ALA D 2 376 ? 160.267 143.640 182.537 1.00 35.67  ? 392 ALA E CA  1 
ATOM   10992 C C   . ALA D 2 376 ? 159.057 144.480 182.912 1.00 38.74  ? 392 ALA E C   1 
ATOM   10993 O O   . ALA D 2 376 ? 158.811 145.528 182.312 1.00 41.77  ? 392 ALA E O   1 
ATOM   10994 C CB  . ALA D 2 376 ? 161.534 144.214 183.180 1.00 29.29  ? 392 ALA E CB  1 
ATOM   10995 N N   . ASN D 2 377 ? 158.309 144.015 183.907 1.00 40.17  ? 393 ASN E N   1 
ATOM   10996 C CA  . ASN D 2 377 ? 157.133 144.712 184.409 1.00 44.09  ? 393 ASN E CA  1 
ATOM   10997 C C   . ASN D 2 377 ? 157.450 145.320 185.767 1.00 40.91  ? 393 ASN E C   1 
ATOM   10998 O O   . ASN D 2 377 ? 157.850 144.606 186.692 1.00 41.54  ? 393 ASN E O   1 
ATOM   10999 C CB  . ASN D 2 377 ? 155.939 143.760 184.517 1.00 45.78  ? 393 ASN E CB  1 
ATOM   11000 C CG  . ASN D 2 377 ? 154.646 144.480 184.834 1.00 48.24  ? 393 ASN E CG  1 
ATOM   11001 O OD1 . ASN D 2 377 ? 154.268 145.430 184.150 1.00 49.75  ? 393 ASN E OD1 1 
ATOM   11002 N ND2 . ASN D 2 377 ? 153.959 144.032 185.876 1.00 47.25  ? 393 ASN E ND2 1 
ATOM   11003 N N   . LEU D 2 378 ? 157.268 146.634 185.884 1.00 38.48  ? 394 LEU E N   1 
ATOM   11004 C CA  . LEU D 2 378 ? 157.538 147.370 187.120 1.00 42.06  ? 394 LEU E CA  1 
ATOM   11005 C C   . LEU D 2 378 ? 156.289 148.165 187.485 1.00 48.45  ? 394 LEU E C   1 
ATOM   11006 O O   . LEU D 2 378 ? 156.129 149.312 187.057 1.00 49.07  ? 394 LEU E O   1 
ATOM   11007 C CB  . LEU D 2 378 ? 158.754 148.277 186.966 1.00 44.79  ? 394 LEU E CB  1 
ATOM   11008 C CG  . LEU D 2 378 ? 159.968 147.940 187.831 1.00 39.28  ? 394 LEU E CG  1 
ATOM   11009 C CD1 . LEU D 2 378 ? 161.002 149.038 187.732 1.00 36.50  ? 394 LEU E CD1 1 
ATOM   11010 C CD2 . LEU D 2 378 ? 159.550 147.728 189.270 1.00 37.07  ? 394 LEU E CD2 1 
ATOM   11011 N N   . ASN D 2 379 ? 155.415 147.550 188.283 1.00 47.43  ? 395 ASN E N   1 
ATOM   11012 C CA  . ASN D 2 379 ? 154.195 148.191 188.775 1.00 49.44  ? 395 ASN E CA  1 
ATOM   11013 C C   . ASN D 2 379 ? 153.328 148.701 187.624 1.00 53.71  ? 395 ASN E C   1 
ATOM   11014 O O   . ASN D 2 379 ? 152.868 149.845 187.620 1.00 57.88  ? 395 ASN E O   1 
ATOM   11015 C CB  . ASN D 2 379 ? 154.526 149.318 189.756 1.00 51.80  ? 395 ASN E CB  1 
ATOM   11016 C CG  . ASN D 2 379 ? 155.101 148.803 191.060 1.00 59.68  ? 395 ASN E CG  1 
ATOM   11017 O OD1 . ASN D 2 379 ? 156.266 149.043 191.376 1.00 61.36  ? 395 ASN E OD1 1 
ATOM   11018 N ND2 . ASN D 2 379 ? 154.284 148.089 191.825 1.00 62.47  ? 395 ASN E ND2 1 
ATOM   11019 N N   . GLY D 2 380 ? 153.106 147.837 186.639 1.00 48.20  ? 396 GLY E N   1 
ATOM   11020 C CA  . GLY D 2 380 ? 152.234 148.157 185.530 1.00 53.57  ? 396 GLY E CA  1 
ATOM   11021 C C   . GLY D 2 380 ? 152.872 148.893 184.375 1.00 54.53  ? 396 GLY E C   1 
ATOM   11022 O O   . GLY D 2 380 ? 152.148 149.346 183.481 1.00 60.63  ? 396 GLY E O   1 
ATOM   11023 N N   . ILE D 2 381 ? 154.193 149.038 184.361 1.00 49.41  ? 397 ILE E N   1 
ATOM   11024 C CA  . ILE D 2 381 ? 154.911 149.659 183.255 1.00 47.63  ? 397 ILE E CA  1 
ATOM   11025 C C   . ILE D 2 381 ? 155.898 148.641 182.706 1.00 47.19  ? 397 ILE E C   1 
ATOM   11026 O O   . ILE D 2 381 ? 156.697 148.075 183.461 1.00 48.61  ? 397 ILE E O   1 
ATOM   11027 C CB  . ILE D 2 381 ? 155.634 150.946 183.689 1.00 45.96  ? 397 ILE E CB  1 
ATOM   11028 C CG1 . ILE D 2 381 ? 154.617 152.004 184.121 1.00 51.44  ? 397 ILE E CG1 1 
ATOM   11029 C CG2 . ILE D 2 381 ? 156.501 151.472 182.557 1.00 44.30  ? 397 ILE E CG2 1 
ATOM   11030 C CD1 . ILE D 2 381 ? 155.140 153.422 184.063 1.00 51.85  ? 397 ILE E CD1 1 
ATOM   11031 N N   . ILE D 2 382 ? 155.843 148.411 181.398 1.00 46.34  ? 398 ILE E N   1 
ATOM   11032 C CA  . ILE D 2 382 ? 156.654 147.397 180.736 1.00 42.23  ? 398 ILE E CA  1 
ATOM   11033 C C   . ILE D 2 382 ? 157.861 148.074 180.104 1.00 42.85  ? 398 ILE E C   1 
ATOM   11034 O O   . ILE D 2 382 ? 157.724 149.101 179.428 1.00 44.41  ? 398 ILE E O   1 
ATOM   11035 C CB  . ILE D 2 382 ? 155.834 146.631 179.684 1.00 46.79  ? 398 ILE E CB  1 
ATOM   11036 C CG1 . ILE D 2 382 ? 154.754 145.789 180.366 1.00 45.39  ? 398 ILE E CG1 1 
ATOM   11037 C CG2 . ILE D 2 382 ? 156.735 145.752 178.835 1.00 44.44  ? 398 ILE E CG2 1 
ATOM   11038 C CD1 . ILE D 2 382 ? 153.720 145.242 179.416 1.00 43.11  ? 398 ILE E CD1 1 
ATOM   11039 N N   . TYR D 2 383 ? 159.043 147.506 180.329 1.00 41.41  ? 399 TYR E N   1 
ATOM   11040 C CA  . TYR D 2 383 ? 160.293 148.034 179.802 1.00 38.53  ? 399 TYR E CA  1 
ATOM   11041 C C   . TYR D 2 383 ? 160.848 147.061 178.772 1.00 37.35  ? 399 TYR E C   1 
ATOM   11042 O O   . TYR D 2 383 ? 161.055 145.882 179.077 1.00 38.61  ? 399 TYR E O   1 
ATOM   11043 C CB  . TYR D 2 383 ? 161.305 148.263 180.925 1.00 35.00  ? 399 TYR E CB  1 
ATOM   11044 C CG  . TYR D 2 383 ? 160.920 149.374 181.871 1.00 36.22  ? 399 TYR E CG  1 
ATOM   11045 C CD1 . TYR D 2 383 ? 161.254 150.691 181.597 1.00 33.62  ? 399 TYR E CD1 1 
ATOM   11046 C CD2 . TYR D 2 383 ? 160.210 149.107 183.032 1.00 36.75  ? 399 TYR E CD2 1 
ATOM   11047 C CE1 . TYR D 2 383 ? 160.898 151.709 182.456 1.00 32.77  ? 399 TYR E CE1 1 
ATOM   11048 C CE2 . TYR D 2 383 ? 159.848 150.119 183.896 1.00 35.62  ? 399 TYR E CE2 1 
ATOM   11049 C CZ  . TYR D 2 383 ? 160.194 151.417 183.603 1.00 33.74  ? 399 TYR E CZ  1 
ATOM   11050 O OH  . TYR D 2 383 ? 159.837 152.430 184.460 1.00 30.87  ? 399 TYR E OH  1 
ATOM   11051 N N   . LEU D 2 384 ? 161.081 147.551 177.558 1.00 35.33  ? 400 LEU E N   1 
ATOM   11052 C CA  . LEU D 2 384 ? 161.737 146.782 176.510 1.00 37.14  ? 400 LEU E CA  1 
ATOM   11053 C C   . LEU D 2 384 ? 163.178 147.261 176.403 1.00 34.60  ? 400 LEU E C   1 
ATOM   11054 O O   . LEU D 2 384 ? 163.425 148.431 176.094 1.00 38.14  ? 400 LEU E O   1 
ATOM   11055 C CB  . LEU D 2 384 ? 161.014 146.937 175.172 1.00 38.94  ? 400 LEU E CB  1 
ATOM   11056 C CG  . LEU D 2 384 ? 159.684 146.202 174.999 1.00 36.64  ? 400 LEU E CG  1 
ATOM   11057 C CD1 . LEU D 2 384 ? 159.208 146.309 173.564 1.00 37.31  ? 400 LEU E CD1 1 
ATOM   11058 C CD2 . LEU D 2 384 ? 159.803 144.746 175.414 1.00 39.42  ? 400 LEU E CD2 1 
ATOM   11059 N N   . LEU D 2 385 ? 164.123 146.362 176.658 1.00 29.22  ? 401 LEU E N   1 
ATOM   11060 C CA  . LEU D 2 385 ? 165.532 146.711 176.761 1.00 30.71  ? 401 LEU E CA  1 
ATOM   11061 C C   . LEU D 2 385 ? 166.333 145.928 175.733 1.00 33.11  ? 401 LEU E C   1 
ATOM   11062 O O   . LEU D 2 385 ? 166.238 144.699 175.671 1.00 35.99  ? 401 LEU E O   1 
ATOM   11063 C CB  . LEU D 2 385 ? 166.058 146.428 178.171 1.00 34.94  ? 401 LEU E CB  1 
ATOM   11064 C CG  . LEU D 2 385 ? 165.155 146.863 179.327 1.00 31.56  ? 401 LEU E CG  1 
ATOM   11065 C CD1 . LEU D 2 385 ? 165.279 145.904 180.495 1.00 28.33  ? 401 LEU E CD1 1 
ATOM   11066 C CD2 . LEU D 2 385 ? 165.481 148.280 179.760 1.00 27.49  ? 401 LEU E CD2 1 
ATOM   11067 N N   . GLY D 2 386 ? 167.126 146.642 174.936 1.00 32.67  ? 402 GLY E N   1 
ATOM   11068 C CA  . GLY D 2 386 ? 168.010 145.990 173.991 1.00 33.50  ? 402 GLY E CA  1 
ATOM   11069 C C   . GLY D 2 386 ? 167.272 145.362 172.822 1.00 38.61  ? 402 GLY E C   1 
ATOM   11070 O O   . GLY D 2 386 ? 166.202 145.812 172.402 1.00 41.99  ? 402 GLY E O   1 
ATOM   11071 N N   . GLY D 2 387 ? 167.866 144.301 172.285 1.00 38.05  ? 403 GLY E N   1 
ATOM   11072 C CA  . GLY D 2 387 ? 167.331 143.640 171.112 1.00 37.54  ? 403 GLY E CA  1 
ATOM   11073 C C   . GLY D 2 387 ? 168.089 144.019 169.859 1.00 39.33  ? 403 GLY E C   1 
ATOM   11074 O O   . GLY D 2 387 ? 169.288 144.300 169.916 1.00 40.51  ? 403 GLY E O   1 
ATOM   11075 N N   . GLU D 2 388 ? 167.406 144.031 168.719 1.00 44.27  ? 404 GLU E N   1 
ATOM   11076 C CA  . GLU D 2 388 ? 168.000 144.470 167.466 1.00 45.24  ? 404 GLU E CA  1 
ATOM   11077 C C   . GLU D 2 388 ? 167.045 145.418 166.761 1.00 46.26  ? 404 GLU E C   1 
ATOM   11078 O O   . GLU D 2 388 ? 165.824 145.245 166.818 1.00 46.69  ? 404 GLU E O   1 
ATOM   11079 C CB  . GLU D 2 388 ? 168.351 143.279 166.561 1.00 44.87  ? 404 GLU E CB  1 
ATOM   11080 C CG  . GLU D 2 388 ? 167.161 142.596 165.916 1.00 52.29  ? 404 GLU E CG  1 
ATOM   11081 C CD  . GLU D 2 388 ? 167.260 141.086 165.970 1.00 56.52  ? 404 GLU E CD  1 
ATOM   11082 O OE1 . GLU D 2 388 ? 168.271 140.573 166.490 1.00 55.45  ? 404 GLU E OE1 1 
ATOM   11083 O OE2 . GLU D 2 388 ? 166.322 140.412 165.497 1.00 61.37  ? 404 GLU E OE2 1 
ATOM   11084 N N   . GLU D 2 389 ? 167.608 146.433 166.114 1.00 47.95  ? 405 GLU E N   1 
ATOM   11085 C CA  . GLU D 2 389 ? 166.843 147.424 165.377 1.00 51.58  ? 405 GLU E CA  1 
ATOM   11086 C C   . GLU D 2 389 ? 167.392 147.540 163.963 1.00 53.71  ? 405 GLU E C   1 
ATOM   11087 O O   . GLU D 2 389 ? 168.560 147.239 163.701 1.00 55.47  ? 405 GLU E O   1 
ATOM   11088 C CB  . GLU D 2 389 ? 166.879 148.790 166.073 1.00 49.65  ? 405 GLU E CB  1 
ATOM   11089 C CG  . GLU D 2 389 ? 168.271 149.267 166.434 1.00 49.60  ? 405 GLU E CG  1 
ATOM   11090 C CD  . GLU D 2 389 ? 168.264 150.647 167.057 1.00 59.25  ? 405 GLU E CD  1 
ATOM   11091 O OE1 . GLU D 2 389 ? 167.218 151.326 166.986 1.00 59.78  ? 405 GLU E OE1 1 
ATOM   11092 O OE2 . GLU D 2 389 ? 169.302 151.053 167.621 1.00 60.11  ? 405 GLU E OE2 1 
ATOM   11093 N N   . ASN D 2 390 ? 166.536 147.979 163.046 1.00 49.39  ? 406 ASN E N   1 
ATOM   11094 C CA  . ASN D 2 390 ? 166.906 148.028 161.641 1.00 54.65  ? 406 ASN E CA  1 
ATOM   11095 C C   . ASN D 2 390 ? 167.828 149.205 161.345 1.00 56.74  ? 406 ASN E C   1 
ATOM   11096 O O   . ASN D 2 390 ? 167.660 150.303 161.882 1.00 58.04  ? 406 ASN E O   1 
ATOM   11097 C CB  . ASN D 2 390 ? 165.657 148.105 160.761 1.00 57.52  ? 406 ASN E CB  1 
ATOM   11098 C CG  . ASN D 2 390 ? 164.594 149.018 161.331 1.00 62.18  ? 406 ASN E CG  1 
ATOM   11099 O OD1 . ASN D 2 390 ? 164.891 150.105 161.825 1.00 65.71  ? 406 ASN E OD1 1 
ATOM   11100 N ND2 . ASN D 2 390 ? 163.342 148.581 161.263 1.00 60.16  ? 406 ASN E ND2 1 
ATOM   11101 N N   . ASP D 2 391 ? 168.820 148.952 160.494 1.00 54.48  ? 407 ASP E N   1 
ATOM   11102 C CA  . ASP D 2 391 ? 169.689 149.981 159.942 1.00 52.27  ? 407 ASP E CA  1 
ATOM   11103 C C   . ASP D 2 391 ? 170.200 149.475 158.603 1.00 52.02  ? 407 ASP E C   1 
ATOM   11104 O O   . ASP D 2 391 ? 170.230 148.266 158.360 1.00 51.75  ? 407 ASP E O   1 
ATOM   11105 C CB  . ASP D 2 391 ? 170.845 150.323 160.891 1.00 54.46  ? 407 ASP E CB  1 
ATOM   11106 C CG  . ASP D 2 391 ? 172.068 149.446 160.676 1.00 56.32  ? 407 ASP E CG  1 
ATOM   11107 O OD1 . ASP D 2 391 ? 171.916 148.213 160.552 1.00 56.29  ? 407 ASP E OD1 1 
ATOM   11108 O OD2 . ASP D 2 391 ? 173.191 149.993 160.663 1.00 52.36  ? 407 ASP E OD2 1 
ATOM   11109 N N   . LEU D 2 392 ? 170.602 150.404 157.730 1.00 53.79  ? 408 LEU E N   1 
ATOM   11110 C CA  . LEU D 2 392 ? 171.028 150.044 156.376 1.00 50.67  ? 408 LEU E CA  1 
ATOM   11111 C C   . LEU D 2 392 ? 169.919 149.240 155.693 1.00 50.52  ? 408 LEU E C   1 
ATOM   11112 O O   . LEU D 2 392 ? 170.033 148.037 155.458 1.00 52.81  ? 408 LEU E O   1 
ATOM   11113 C CB  . LEU D 2 392 ? 172.352 149.269 156.398 1.00 44.00  ? 408 LEU E CB  1 
ATOM   11114 C CG  . LEU D 2 392 ? 173.596 150.023 156.867 1.00 41.39  ? 408 LEU E CG  1 
ATOM   11115 C CD1 . LEU D 2 392 ? 174.849 149.230 156.546 1.00 36.44  ? 408 LEU E CD1 1 
ATOM   11116 C CD2 . LEU D 2 392 ? 173.657 151.404 156.241 1.00 42.35  ? 408 LEU E CD2 1 
ATOM   11117 N N   . ASP D 2 393 ? 168.838 149.947 155.364 1.00 50.66  ? 409 ASP E N   1 
ATOM   11118 C CA  . ASP D 2 393 ? 167.492 149.446 155.614 1.00 51.77  ? 409 ASP E CA  1 
ATOM   11119 C C   . ASP D 2 393 ? 167.116 148.231 154.780 1.00 51.83  ? 409 ASP E C   1 
ATOM   11120 O O   . ASP D 2 393 ? 166.128 148.241 154.039 1.00 55.05  ? 409 ASP E O   1 
ATOM   11121 C CB  . ASP D 2 393 ? 166.483 150.564 155.349 1.00 59.05  ? 409 ASP E CB  1 
ATOM   11122 C CG  . ASP D 2 393 ? 166.661 151.189 153.977 1.00 64.93  ? 409 ASP E CG  1 
ATOM   11123 O OD1 . ASP D 2 393 ? 167.726 151.794 153.732 1.00 62.00  ? 409 ASP E OD1 1 
ATOM   11124 O OD2 . ASP D 2 393 ? 165.741 151.066 153.141 1.00 66.48  ? 409 ASP E OD2 1 
ATOM   11125 N N   . PHE D 2 394 ? 167.903 147.170 154.935 1.00 47.67  ? 410 PHE E N   1 
ATOM   11126 C CA  . PHE D 2 394 ? 167.486 145.811 154.635 1.00 44.22  ? 410 PHE E CA  1 
ATOM   11127 C C   . PHE D 2 394 ? 167.961 144.838 155.702 1.00 46.05  ? 410 PHE E C   1 
ATOM   11128 O O   . PHE D 2 394 ? 167.655 143.646 155.607 1.00 50.83  ? 410 PHE E O   1 
ATOM   11129 C CB  . PHE D 2 394 ? 168.009 145.361 153.262 1.00 43.20  ? 410 PHE E CB  1 
ATOM   11130 C CG  . PHE D 2 394 ? 167.569 146.236 152.127 1.00 40.83  ? 410 PHE E CG  1 
ATOM   11131 C CD1 . PHE D 2 394 ? 166.274 146.167 151.645 1.00 41.71  ? 410 PHE E CD1 1 
ATOM   11132 C CD2 . PHE D 2 394 ? 168.450 147.123 151.538 1.00 35.70  ? 410 PHE E CD2 1 
ATOM   11133 C CE1 . PHE D 2 394 ? 165.868 146.969 150.603 1.00 37.81  ? 410 PHE E CE1 1 
ATOM   11134 C CE2 . PHE D 2 394 ? 168.047 147.925 150.497 1.00 38.28  ? 410 PHE E CE2 1 
ATOM   11135 C CZ  . PHE D 2 394 ? 166.755 147.848 150.028 1.00 38.46  ? 410 PHE E CZ  1 
ATOM   11136 N N   . PHE D 2 395 ? 168.688 145.309 156.714 1.00 46.49  ? 411 PHE E N   1 
ATOM   11137 C CA  . PHE D 2 395 ? 169.317 144.477 157.728 1.00 46.53  ? 411 PHE E CA  1 
ATOM   11138 C C   . PHE D 2 395 ? 169.030 145.063 159.107 1.00 51.52  ? 411 PHE E C   1 
ATOM   11139 O O   . PHE D 2 395 ? 168.396 146.113 159.240 1.00 51.11  ? 411 PHE E O   1 
ATOM   11140 C CB  . PHE D 2 395 ? 170.826 144.366 157.475 1.00 44.10  ? 411 PHE E CB  1 
ATOM   11141 C CG  . PHE D 2 395 ? 171.185 144.236 156.022 1.00 47.50  ? 411 PHE E CG  1 
ATOM   11142 C CD1 . PHE D 2 395 ? 171.036 143.027 155.363 1.00 46.13  ? 411 PHE E CD1 1 
ATOM   11143 C CD2 . PHE D 2 395 ? 171.659 145.325 155.311 1.00 46.74  ? 411 PHE E CD2 1 
ATOM   11144 C CE1 . PHE D 2 395 ? 171.360 142.906 154.027 1.00 41.28  ? 411 PHE E CE1 1 
ATOM   11145 C CE2 . PHE D 2 395 ? 171.983 145.210 153.975 1.00 41.65  ? 411 PHE E CE2 1 
ATOM   11146 C CZ  . PHE D 2 395 ? 171.834 143.998 153.333 1.00 41.64  ? 411 PHE E CZ  1 
ATOM   11147 N N   . THR D 2 396 ? 169.503 144.372 160.142 1.00 54.02  ? 412 THR E N   1 
ATOM   11148 C CA  . THR D 2 396 ? 169.282 144.768 161.524 1.00 49.81  ? 412 THR E CA  1 
ATOM   11149 C C   . THR D 2 396 ? 170.608 145.080 162.204 1.00 51.04  ? 412 THR E C   1 
ATOM   11150 O O   . THR D 2 396 ? 171.678 144.660 161.757 1.00 53.39  ? 412 THR E O   1 
ATOM   11151 C CB  . THR D 2 396 ? 168.546 143.676 162.312 1.00 49.68  ? 412 THR E CB  1 
ATOM   11152 O OG1 . THR D 2 396 ? 169.147 142.404 162.047 1.00 53.48  ? 412 THR E OG1 1 
ATOM   11153 C CG2 . THR D 2 396 ? 167.081 143.628 161.916 1.00 50.87  ? 412 THR E CG2 1 
ATOM   11154 N N   . LYS D 2 397 ? 170.520 145.829 163.304 1.00 50.11  ? 413 LYS E N   1 
ATOM   11155 C CA  . LYS D 2 397 ? 171.669 146.258 164.084 1.00 46.99  ? 413 LYS E CA  1 
ATOM   11156 C C   . LYS D 2 397 ? 171.341 146.091 165.562 1.00 46.46  ? 413 LYS E C   1 
ATOM   11157 O O   . LYS D 2 397 ? 170.195 146.331 165.968 1.00 47.76  ? 413 LYS E O   1 
ATOM   11158 C CB  . LYS D 2 397 ? 172.017 147.721 163.776 1.00 47.60  ? 413 LYS E CB  1 
ATOM   11159 C CG  . LYS D 2 397 ? 172.947 148.398 164.763 1.00 48.61  ? 413 LYS E CG  1 
ATOM   11160 C CD  . LYS D 2 397 ? 172.881 149.908 164.620 1.00 47.92  ? 413 LYS E CD  1 
ATOM   11161 C CE  . LYS D 2 397 ? 171.445 150.401 164.640 1.00 46.86  ? 413 LYS E CE  1 
ATOM   11162 N NZ  . LYS D 2 397 ? 171.365 151.879 164.484 1.00 53.33  ? 413 LYS E NZ  1 
ATOM   11163 N N   . PRO D 2 398 ? 172.307 145.673 166.383 1.00 46.19  ? 414 PRO E N   1 
ATOM   11164 C CA  . PRO D 2 398 ? 172.040 145.534 167.821 1.00 45.52  ? 414 PRO E CA  1 
ATOM   11165 C C   . PRO D 2 398 ? 171.609 146.855 168.442 1.00 45.10  ? 414 PRO E C   1 
ATOM   11166 O O   . PRO D 2 398 ? 172.132 147.921 168.112 1.00 46.66  ? 414 PRO E O   1 
ATOM   11167 C CB  . PRO D 2 398 ? 173.382 145.053 168.389 1.00 41.97  ? 414 PRO E CB  1 
ATOM   11168 C CG  . PRO D 2 398 ? 174.391 145.320 167.316 1.00 45.00  ? 414 PRO E CG  1 
ATOM   11169 C CD  . PRO D 2 398 ? 173.652 145.195 166.027 1.00 45.67  ? 414 PRO E CD  1 
ATOM   11170 N N   . SER D 2 399 ? 170.651 146.771 169.360 1.00 39.89  ? 415 SER E N   1 
ATOM   11171 C CA  . SER D 2 399 ? 169.999 147.938 169.933 1.00 39.39  ? 415 SER E CA  1 
ATOM   11172 C C   . SER D 2 399 ? 170.362 148.102 171.402 1.00 42.83  ? 415 SER E C   1 
ATOM   11173 O O   . SER D 2 399 ? 170.549 147.123 172.130 1.00 42.71  ? 415 SER E O   1 
ATOM   11174 C CB  . SER D 2 399 ? 168.479 147.838 169.790 1.00 40.05  ? 415 SER E CB  1 
ATOM   11175 O OG  . SER D 2 399 ? 167.836 148.955 170.376 1.00 44.36  ? 415 SER E OG  1 
ATOM   11176 N N   . ARG D 2 400 ? 170.460 149.358 171.828 1.00 44.63  ? 416 ARG E N   1 
ATOM   11177 C CA  . ARG D 2 400 ? 170.694 149.729 173.218 1.00 40.32  ? 416 ARG E CA  1 
ATOM   11178 C C   . ARG D 2 400 ? 169.652 150.739 173.675 1.00 41.26  ? 416 ARG E C   1 
ATOM   11179 O O   . ARG D 2 400 ? 169.950 151.684 174.410 1.00 43.39  ? 416 ARG E O   1 
ATOM   11180 C CB  . ARG D 2 400 ? 172.106 150.274 173.408 1.00 40.11  ? 416 ARG E CB  1 
ATOM   11181 C CG  . ARG D 2 400 ? 172.475 151.398 172.458 1.00 45.91  ? 416 ARG E CG  1 
ATOM   11182 C CD  . ARG D 2 400 ? 173.756 152.086 172.895 1.00 45.46  ? 416 ARG E CD  1 
ATOM   11183 N NE  . ARG D 2 400 ? 174.857 151.144 173.041 1.00 46.62  ? 416 ARG E NE  1 
ATOM   11184 C CZ  . ARG D 2 400 ? 175.983 151.403 173.692 1.00 49.78  ? 416 ARG E CZ  1 
ATOM   11185 N NH1 . ARG D 2 400 ? 176.188 152.570 174.279 1.00 51.47  ? 416 ARG E NH1 1 
ATOM   11186 N NH2 . ARG D 2 400 ? 176.925 150.466 173.758 1.00 49.15  ? 416 ARG E NH2 1 
ATOM   11187 N N   . LEU D 2 401 ? 168.411 150.546 173.246 1.00 42.07  ? 417 LEU E N   1 
ATOM   11188 C CA  . LEU D 2 401 ? 167.315 151.455 173.537 1.00 42.66  ? 417 LEU E CA  1 
ATOM   11189 C C   . LEU D 2 401 ? 166.483 150.950 174.708 1.00 42.74  ? 417 LEU E C   1 
ATOM   11190 O O   . LEU D 2 401 ? 166.462 149.758 175.023 1.00 43.18  ? 417 LEU E O   1 
ATOM   11191 C CB  . LEU D 2 401 ? 166.419 151.627 172.308 1.00 44.10  ? 417 LEU E CB  1 
ATOM   11192 C CG  . LEU D 2 401 ? 166.568 152.903 171.482 1.00 51.74  ? 417 LEU E CG  1 
ATOM   11193 C CD1 . LEU D 2 401 ? 167.910 152.937 170.771 1.00 51.63  ? 417 LEU E CD1 1 
ATOM   11194 C CD2 . LEU D 2 401 ? 165.427 153.006 170.488 1.00 53.52  ? 417 LEU E CD2 1 
ATOM   11195 N N   . ILE D 2 402 ? 165.790 151.885 175.354 1.00 41.10  ? 418 ILE E N   1 
ATOM   11196 C CA  . ILE D 2 402 ? 164.821 151.586 176.399 1.00 39.60  ? 418 ILE E CA  1 
ATOM   11197 C C   . ILE D 2 402 ? 163.479 152.159 175.970 1.00 40.74  ? 418 ILE E C   1 
ATOM   11198 O O   . ILE D 2 402 ? 163.399 153.322 175.560 1.00 44.85  ? 418 ILE E O   1 
ATOM   11199 C CB  . ILE D 2 402 ? 165.247 152.158 177.764 1.00 40.29  ? 418 ILE E CB  1 
ATOM   11200 C CG1 . ILE D 2 402 ? 166.633 151.648 178.156 1.00 38.50  ? 418 ILE E CG1 1 
ATOM   11201 C CG2 . ILE D 2 402 ? 164.234 151.794 178.835 1.00 42.61  ? 418 ILE E CG2 1 
ATOM   11202 C CD1 . ILE D 2 402 ? 167.445 152.646 178.935 1.00 34.30  ? 418 ILE E CD1 1 
ATOM   11203 N N   . GLN D 2 403 ? 162.433 151.342 176.049 1.00 40.42  ? 419 GLN E N   1 
ATOM   11204 C CA  . GLN D 2 403 ? 161.080 151.769 175.727 1.00 41.50  ? 419 GLN E CA  1 
ATOM   11205 C C   . GLN D 2 403 ? 160.151 151.415 176.876 1.00 45.22  ? 419 GLN E C   1 
ATOM   11206 O O   . GLN D 2 403 ? 160.268 150.341 177.471 1.00 46.57  ? 419 GLN E O   1 
ATOM   11207 C CB  . GLN D 2 403 ? 160.576 151.117 174.440 1.00 44.69  ? 419 GLN E CB  1 
ATOM   11208 C CG  . GLN D 2 403 ? 161.212 151.653 173.176 1.00 47.79  ? 419 GLN E CG  1 
ATOM   11209 C CD  . GLN D 2 403 ? 160.495 151.177 171.935 1.00 50.49  ? 419 GLN E CD  1 
ATOM   11210 O OE1 . GLN D 2 403 ? 159.596 151.846 171.431 1.00 54.65  ? 419 GLN E OE1 1 
ATOM   11211 N NE2 . GLN D 2 403 ? 160.883 150.010 171.439 1.00 48.41  ? 419 GLN E NE2 1 
ATOM   11212 N N   . CYS D 2 404 ? 159.226 152.319 177.179 1.00 48.90  ? 420 CYS E N   1 
ATOM   11213 C CA  . CYS D 2 404 ? 158.245 152.122 178.234 1.00 49.24  ? 420 CYS E CA  1 
ATOM   11214 C C   . CYS D 2 404 ? 156.855 151.996 177.630 1.00 53.51  ? 420 CYS E C   1 
ATOM   11215 O O   . CYS D 2 404 ? 156.529 152.673 176.651 1.00 56.70  ? 420 CYS E O   1 
ATOM   11216 C CB  . CYS D 2 404 ? 158.269 153.278 179.234 1.00 49.98  ? 420 CYS E CB  1 
ATOM   11217 S SG  . CYS D 2 404 ? 159.912 153.722 179.804 1.00 66.50  ? 420 CYS E SG  1 
ATOM   11218 N N   . PHE D 2 405 ? 156.041 151.123 178.214 1.00 52.49  ? 421 PHE E N   1 
ATOM   11219 C CA  . PHE D 2 405 ? 154.657 150.927 177.790 1.00 53.04  ? 421 PHE E CA  1 
ATOM   11220 C C   . PHE D 2 405 ? 153.780 150.924 179.037 1.00 55.65  ? 421 PHE E C   1 
ATOM   11221 O O   . PHE D 2 405 ? 153.695 149.915 179.742 1.00 53.45  ? 421 PHE E O   1 
ATOM   11222 C CB  . PHE D 2 405 ? 154.497 149.634 177.000 1.00 54.85  ? 421 PHE E CB  1 
ATOM   11223 C CG  . PHE D 2 405 ? 153.179 149.521 176.297 1.00 60.87  ? 421 PHE E CG  1 
ATOM   11224 C CD1 . PHE D 2 405 ? 152.969 150.161 175.089 1.00 61.58  ? 421 PHE E CD1 1 
ATOM   11225 C CD2 . PHE D 2 405 ? 152.146 148.785 176.850 1.00 60.46  ? 421 PHE E CD2 1 
ATOM   11226 C CE1 . PHE D 2 405 ? 151.758 150.063 174.442 1.00 65.08  ? 421 PHE E CE1 1 
ATOM   11227 C CE2 . PHE D 2 405 ? 150.931 148.686 176.207 1.00 61.49  ? 421 PHE E CE2 1 
ATOM   11228 C CZ  . PHE D 2 405 ? 150.737 149.325 175.001 1.00 64.30  ? 421 PHE E CZ  1 
ATOM   11229 N N   . ASP D 2 406 ? 153.130 152.052 179.307 1.00 59.05  ? 422 ASP E N   1 
ATOM   11230 C CA  . ASP D 2 406 ? 152.225 152.152 180.445 1.00 63.96  ? 422 ASP E CA  1 
ATOM   11231 C C   . ASP D 2 406 ? 150.946 151.387 180.131 1.00 67.72  ? 422 ASP E C   1 
ATOM   11232 O O   . ASP D 2 406 ? 150.193 151.766 179.230 1.00 69.75  ? 422 ASP E O   1 
ATOM   11233 C CB  . ASP D 2 406 ? 151.929 153.615 180.755 1.00 69.25  ? 422 ASP E CB  1 
ATOM   11234 C CG  . ASP D 2 406 ? 151.417 153.822 182.166 1.00 72.76  ? 422 ASP E CG  1 
ATOM   11235 O OD1 . ASP D 2 406 ? 150.917 152.851 182.770 1.00 71.86  ? 422 ASP E OD1 1 
ATOM   11236 O OD2 . ASP D 2 406 ? 151.520 154.957 182.675 1.00 73.96  ? 422 ASP E OD2 1 
ATOM   11237 N N   . THR D 2 407 ? 150.696 150.307 180.873 1.00 65.18  ? 423 THR E N   1 
ATOM   11238 C CA  . THR D 2 407 ? 149.514 149.491 180.630 1.00 68.31  ? 423 THR E CA  1 
ATOM   11239 C C   . THR D 2 407 ? 148.225 150.163 181.082 1.00 73.04  ? 423 THR E C   1 
ATOM   11240 O O   . THR D 2 407 ? 147.142 149.652 180.774 1.00 72.82  ? 423 THR E O   1 
ATOM   11241 C CB  . THR D 2 407 ? 149.657 148.135 181.322 1.00 66.69  ? 423 THR E CB  1 
ATOM   11242 O OG1 . THR D 2 407 ? 149.510 148.301 182.738 1.00 69.61  ? 423 THR E OG1 1 
ATOM   11243 C CG2 . THR D 2 407 ? 151.016 147.528 181.023 1.00 59.50  ? 423 THR E CG2 1 
ATOM   11244 N N   . GLU D 2 408 ? 148.308 151.281 181.802 1.00 74.68  ? 424 GLU E N   1 
ATOM   11245 C CA  . GLU D 2 408 ? 147.117 152.007 182.231 1.00 74.75  ? 424 GLU E CA  1 
ATOM   11246 C C   . GLU D 2 408 ? 146.679 153.025 181.181 1.00 74.75  ? 424 GLU E C   1 
ATOM   11247 O O   . GLU D 2 408 ? 145.550 152.968 180.685 1.00 77.98  ? 424 GLU E O   1 
ATOM   11248 C CB  . GLU D 2 408 ? 147.376 152.695 183.576 1.00 75.30  ? 424 GLU E CB  1 
ATOM   11249 C CG  . GLU D 2 408 ? 147.255 151.775 184.780 1.00 77.31  ? 424 GLU E CG  1 
ATOM   11250 C CD  . GLU D 2 408 ? 148.586 151.178 185.197 1.00 80.05  ? 424 GLU E CD  1 
ATOM   11251 O OE1 . GLU D 2 408 ? 149.347 150.739 184.310 1.00 76.02  ? 424 GLU E OE1 1 
ATOM   11252 O OE2 . GLU D 2 408 ? 148.870 151.146 186.413 1.00 83.80  ? 424 GLU E OE2 1 
ATOM   11253 N N   . THR D 2 409 ? 147.564 153.959 180.833 1.00 73.78  ? 425 THR E N   1 
ATOM   11254 C CA  . THR D 2 409 ? 147.245 154.977 179.841 1.00 75.80  ? 425 THR E CA  1 
ATOM   11255 C C   . THR D 2 409 ? 147.453 154.501 178.411 1.00 76.17  ? 425 THR E C   1 
ATOM   11256 O O   . THR D 2 409 ? 147.063 155.215 177.480 1.00 77.62  ? 425 THR E O   1 
ATOM   11257 C CB  . THR D 2 409 ? 148.085 156.235 180.082 1.00 75.90  ? 425 THR E CB  1 
ATOM   11258 O OG1 . THR D 2 409 ? 149.317 156.137 179.358 1.00 76.87  ? 425 THR E OG1 1 
ATOM   11259 C CG2 . THR D 2 409 ? 148.387 156.399 181.563 1.00 74.07  ? 425 THR E CG2 1 
ATOM   11260 N N   . ASP D 2 410 ? 148.050 153.322 178.218 1.00 75.36  ? 426 ASP E N   1 
ATOM   11261 C CA  . ASP D 2 410 ? 148.302 152.758 176.890 1.00 74.63  ? 426 ASP E CA  1 
ATOM   11262 C C   . ASP D 2 410 ? 149.105 153.725 176.020 1.00 74.78  ? 426 ASP E C   1 
ATOM   11263 O O   . ASP D 2 410 ? 148.699 154.093 174.916 1.00 76.63  ? 426 ASP E O   1 
ATOM   11264 C CB  . ASP D 2 410 ? 146.993 152.355 176.206 1.00 75.69  ? 426 ASP E CB  1 
ATOM   11265 C CG  . ASP D 2 410 ? 146.446 151.040 176.726 1.00 77.65  ? 426 ASP E CG  1 
ATOM   11266 O OD1 . ASP D 2 410 ? 147.154 150.016 176.625 1.00 77.41  ? 426 ASP E OD1 1 
ATOM   11267 O OD2 . ASP D 2 410 ? 145.308 151.029 177.239 1.00 78.35  ? 426 ASP E OD2 1 
ATOM   11268 N N   . LYS D 2 411 ? 150.260 154.142 176.534 1.00 74.64  ? 427 LYS E N   1 
ATOM   11269 C CA  . LYS D 2 411 ? 151.150 155.057 175.836 1.00 75.72  ? 427 LYS E CA  1 
ATOM   11270 C C   . LYS D 2 411 ? 152.563 154.496 175.846 1.00 69.56  ? 427 LYS E C   1 
ATOM   11271 O O   . LYS D 2 411 ? 152.979 153.840 176.805 1.00 71.54  ? 427 LYS E O   1 
ATOM   11272 C CB  . LYS D 2 411 ? 151.137 156.453 176.475 1.00 74.26  ? 427 LYS E CB  1 
ATOM   11273 C CG  . LYS D 2 411 ? 149.842 157.222 176.268 1.00 76.39  ? 427 LYS E CG  1 
ATOM   11274 C CD  . LYS D 2 411 ? 150.072 158.722 176.350 1.00 81.93  ? 427 LYS E CD  1 
ATOM   11275 C CE  . LYS D 2 411 ? 149.397 159.449 175.197 1.00 79.68  ? 427 LYS E CE  1 
ATOM   11276 N NZ  . LYS D 2 411 ? 149.304 160.915 175.439 1.00 74.21  ? 427 LYS E NZ  1 
ATOM   11277 N N   . CYS D 2 412 ? 153.300 154.760 174.771 1.00 63.47  ? 428 CYS E N   1 
ATOM   11278 C CA  . CYS D 2 412 ? 154.658 154.263 174.604 1.00 65.82  ? 428 CYS E CA  1 
ATOM   11279 C C   . CYS D 2 412 ? 155.625 155.428 174.448 1.00 67.29  ? 428 CYS E C   1 
ATOM   11280 O O   . CYS D 2 412 ? 155.340 156.393 173.733 1.00 69.15  ? 428 CYS E O   1 
ATOM   11281 C CB  . CYS D 2 412 ? 154.761 153.330 173.394 1.00 67.10  ? 428 CYS E CB  1 
ATOM   11282 S SG  . CYS D 2 412 ? 156.414 152.657 173.111 1.00 66.29  ? 428 CYS E SG  1 
ATOM   11283 N N   . HIS D 2 413 ? 156.771 155.330 175.120 1.00 63.62  ? 429 HIS E N   1 
ATOM   11284 C CA  . HIS D 2 413 ? 157.779 156.380 175.101 1.00 62.36  ? 429 HIS E CA  1 
ATOM   11285 C C   . HIS D 2 413 ? 159.158 155.759 174.942 1.00 54.84  ? 429 HIS E C   1 
ATOM   11286 O O   . HIS D 2 413 ? 159.376 154.587 175.258 1.00 53.75  ? 429 HIS E O   1 
ATOM   11287 C CB  . HIS D 2 413 ? 157.739 157.232 176.378 1.00 64.00  ? 429 HIS E CB  1 
ATOM   11288 C CG  . HIS D 2 413 ? 156.369 157.704 176.751 1.00 70.89  ? 429 HIS E CG  1 
ATOM   11289 N ND1 . HIS D 2 413 ? 155.552 157.007 177.616 1.00 69.30  ? 429 HIS E ND1 1 
ATOM   11290 C CD2 . HIS D 2 413 ? 155.674 158.805 176.382 1.00 71.92  ? 429 HIS E CD2 1 
ATOM   11291 C CE1 . HIS D 2 413 ? 154.412 157.658 177.761 1.00 73.16  ? 429 HIS E CE1 1 
ATOM   11292 N NE2 . HIS D 2 413 ? 154.460 158.752 177.023 1.00 74.25  ? 429 HIS E NE2 1 
ATOM   11293 N N   . VAL D 2 414 ? 160.093 156.565 174.448 1.00 55.08  ? 430 VAL E N   1 
ATOM   11294 C CA  . VAL D 2 414 ? 161.491 156.175 174.304 1.00 52.40  ? 430 VAL E CA  1 
ATOM   11295 C C   . VAL D 2 414 ? 162.313 157.055 175.234 1.00 50.57  ? 430 VAL E C   1 
ATOM   11296 O O   . VAL D 2 414 ? 162.232 158.288 175.162 1.00 52.85  ? 430 VAL E O   1 
ATOM   11297 C CB  . VAL D 2 414 ? 161.977 156.303 172.852 1.00 55.72  ? 430 VAL E CB  1 
ATOM   11298 C CG1 . VAL D 2 414 ? 163.493 156.240 172.794 1.00 51.64  ? 430 VAL E CG1 1 
ATOM   11299 C CG2 . VAL D 2 414 ? 161.372 155.210 171.995 1.00 53.29  ? 430 VAL E CG2 1 
ATOM   11300 N N   . LYS D 2 415 ? 163.094 156.427 176.104 1.00 47.04  ? 431 LYS E N   1 
ATOM   11301 C CA  . LYS D 2 415 ? 163.875 157.179 177.072 1.00 47.43  ? 431 LYS E CA  1 
ATOM   11302 C C   . LYS D 2 415 ? 165.014 157.920 176.375 1.00 50.91  ? 431 LYS E C   1 
ATOM   11303 O O   . LYS D 2 415 ? 165.620 157.389 175.439 1.00 53.82  ? 431 LYS E O   1 
ATOM   11304 C CB  . LYS D 2 415 ? 164.431 156.251 178.149 1.00 45.02  ? 431 LYS E CB  1 
ATOM   11305 C CG  . LYS D 2 415 ? 163.372 155.405 178.826 1.00 41.60  ? 431 LYS E CG  1 
ATOM   11306 C CD  . LYS D 2 415 ? 162.183 156.252 179.239 1.00 45.15  ? 431 LYS E CD  1 
ATOM   11307 C CE  . LYS D 2 415 ? 162.203 156.558 180.723 1.00 46.26  ? 431 LYS E CE  1 
ATOM   11308 N NZ  . LYS D 2 415 ? 160.910 157.137 181.179 1.00 51.25  ? 431 LYS E NZ  1 
ATOM   11309 N N   . PRO D 2 416 ? 165.318 159.150 176.798 1.00 51.04  ? 432 PRO E N   1 
ATOM   11310 C CA  . PRO D 2 416 ? 166.415 159.896 176.160 1.00 51.59  ? 432 PRO E CA  1 
ATOM   11311 C C   . PRO D 2 416 ? 167.766 159.214 176.272 1.00 51.79  ? 432 PRO E C   1 
ATOM   11312 O O   . PRO D 2 416 ? 168.588 159.335 175.355 1.00 52.08  ? 432 PRO E O   1 
ATOM   11313 C CB  . PRO D 2 416 ? 166.401 161.238 176.906 1.00 50.14  ? 432 PRO E CB  1 
ATOM   11314 C CG  . PRO D 2 416 ? 165.023 161.347 177.472 1.00 50.05  ? 432 PRO E CG  1 
ATOM   11315 C CD  . PRO D 2 416 ? 164.620 159.950 177.816 1.00 49.51  ? 432 PRO E CD  1 
ATOM   11316 N N   . TYR D 2 417 ? 168.025 158.506 177.366 1.00 49.13  ? 433 TYR E N   1 
ATOM   11317 C CA  . TYR D 2 417 ? 169.303 157.845 177.570 1.00 46.30  ? 433 TYR E CA  1 
ATOM   11318 C C   . TYR D 2 417 ? 169.291 156.453 176.939 1.00 45.07  ? 433 TYR E C   1 
ATOM   11319 O O   . TYR D 2 417 ? 168.270 155.973 176.439 1.00 43.59  ? 433 TYR E O   1 
ATOM   11320 C CB  . TYR D 2 417 ? 169.629 157.764 179.062 1.00 45.01  ? 433 TYR E CB  1 
ATOM   11321 C CG  . TYR D 2 417 ? 168.464 157.328 179.925 1.00 42.97  ? 433 TYR E CG  1 
ATOM   11322 C CD1 . TYR D 2 417 ? 167.534 158.246 180.390 1.00 43.66  ? 433 TYR E CD1 1 
ATOM   11323 C CD2 . TYR D 2 417 ? 168.297 155.996 180.273 1.00 40.72  ? 433 TYR E CD2 1 
ATOM   11324 C CE1 . TYR D 2 417 ? 166.471 157.848 181.170 1.00 43.06  ? 433 TYR E CE1 1 
ATOM   11325 C CE2 . TYR D 2 417 ? 167.240 155.592 181.053 1.00 38.41  ? 433 TYR E CE2 1 
ATOM   11326 C CZ  . TYR D 2 417 ? 166.330 156.520 181.499 1.00 41.54  ? 433 TYR E CZ  1 
ATOM   11327 O OH  . TYR D 2 417 ? 165.273 156.116 182.280 1.00 39.69  ? 433 TYR E OH  1 
ATOM   11328 N N   . VAL D 2 418 ? 170.454 155.801 176.963 1.00 44.40  ? 434 VAL E N   1 
ATOM   11329 C CA  . VAL D 2 418 ? 170.628 154.488 176.359 1.00 42.08  ? 434 VAL E CA  1 
ATOM   11330 C C   . VAL D 2 418 ? 171.322 153.567 177.353 1.00 38.18  ? 434 VAL E C   1 
ATOM   11331 O O   . VAL D 2 418 ? 171.954 154.009 178.314 1.00 39.46  ? 434 VAL E O   1 
ATOM   11332 C CB  . VAL D 2 418 ? 171.427 154.551 175.038 1.00 41.61  ? 434 VAL E CB  1 
ATOM   11333 C CG1 . VAL D 2 418 ? 170.586 155.168 173.934 1.00 40.47  ? 434 VAL E CG1 1 
ATOM   11334 C CG2 . VAL D 2 418 ? 172.718 155.329 175.233 1.00 39.73  ? 434 VAL E CG2 1 
ATOM   11335 N N   . LEU D 2 419 ? 171.192 152.267 177.105 1.00 37.53  ? 435 LEU E N   1 
ATOM   11336 C CA  . LEU D 2 419 ? 171.813 151.273 177.962 1.00 38.36  ? 435 LEU E CA  1 
ATOM   11337 C C   . LEU D 2 419 ? 173.331 151.285 177.783 1.00 40.85  ? 435 LEU E C   1 
ATOM   11338 O O   . LEU D 2 419 ? 173.834 151.610 176.705 1.00 40.03  ? 435 LEU E O   1 
ATOM   11339 C CB  . LEU D 2 419 ? 171.264 149.885 177.648 1.00 39.21  ? 435 LEU E CB  1 
ATOM   11340 C CG  . LEU D 2 419 ? 169.838 149.595 178.115 1.00 37.63  ? 435 LEU E CG  1 
ATOM   11341 C CD1 . LEU D 2 419 ? 169.190 148.543 177.240 1.00 33.95  ? 435 LEU E CD1 1 
ATOM   11342 C CD2 . LEU D 2 419 ? 169.833 149.159 179.567 1.00 35.99  ? 435 LEU E CD2 1 
ATOM   11343 N N   . PRO D 2 420 ? 174.085 150.943 178.832 1.00 42.03  ? 436 PRO E N   1 
ATOM   11344 C CA  . PRO D 2 420 ? 175.549 150.878 178.691 1.00 43.50  ? 436 PRO E CA  1 
ATOM   11345 C C   . PRO D 2 420 ? 176.029 149.809 177.723 1.00 43.04  ? 436 PRO E C   1 
ATOM   11346 O O   . PRO D 2 420 ? 177.136 149.941 177.188 1.00 46.64  ? 436 PRO E O   1 
ATOM   11347 C CB  . PRO D 2 420 ? 176.033 150.595 180.119 1.00 41.40  ? 436 PRO E CB  1 
ATOM   11348 C CG  . PRO D 2 420 ? 174.858 150.045 180.828 1.00 38.24  ? 436 PRO E CG  1 
ATOM   11349 C CD  . PRO D 2 420 ? 173.643 150.639 180.201 1.00 36.71  ? 436 PRO E CD  1 
ATOM   11350 N N   . PHE D 2 421 ? 175.246 148.760 177.481 1.00 39.28  ? 437 PHE E N   1 
ATOM   11351 C CA  . PHE D 2 421 ? 175.594 147.743 176.501 1.00 38.48  ? 437 PHE E CA  1 
ATOM   11352 C C   . PHE D 2 421 ? 174.461 147.590 175.497 1.00 41.28  ? 437 PHE E C   1 
ATOM   11353 O O   . PHE D 2 421 ? 173.359 148.110 175.686 1.00 41.88  ? 437 PHE E O   1 
ATOM   11354 C CB  . PHE D 2 421 ? 175.918 146.385 177.153 1.00 39.42  ? 437 PHE E CB  1 
ATOM   11355 C CG  . PHE D 2 421 ? 175.084 146.057 178.364 1.00 40.85  ? 437 PHE E CG  1 
ATOM   11356 C CD1 . PHE D 2 421 ? 173.702 146.124 178.324 1.00 39.97  ? 437 PHE E CD1 1 
ATOM   11357 C CD2 . PHE D 2 421 ? 175.690 145.641 179.537 1.00 40.22  ? 437 PHE E CD2 1 
ATOM   11358 C CE1 . PHE D 2 421 ? 172.947 145.810 179.438 1.00 32.50  ? 437 PHE E CE1 1 
ATOM   11359 C CE2 . PHE D 2 421 ? 174.939 145.322 180.648 1.00 36.56  ? 437 PHE E CE2 1 
ATOM   11360 C CZ  . PHE D 2 421 ? 173.566 145.407 180.598 1.00 31.83  ? 437 PHE E CZ  1 
ATOM   11361 N N   . ALA D 2 422 ? 174.752 146.875 174.413 1.00 42.97  ? 438 ALA E N   1 
ATOM   11362 C CA  . ALA D 2 422 ? 173.803 146.660 173.331 1.00 42.39  ? 438 ALA E CA  1 
ATOM   11363 C C   . ALA D 2 422 ? 173.795 145.191 172.937 1.00 38.56  ? 438 ALA E C   1 
ATOM   11364 O O   . ALA D 2 422 ? 174.770 144.465 173.143 1.00 44.19  ? 438 ALA E O   1 
ATOM   11365 C CB  . ALA D 2 422 ? 174.136 147.525 172.110 1.00 38.44  ? 438 ALA E CB  1 
ATOM   11366 N N   . GLY D 2 423 ? 172.670 144.755 172.366 1.00 33.39  ? 439 GLY E N   1 
ATOM   11367 C CA  . GLY D 2 423 ? 172.528 143.408 171.851 1.00 34.70  ? 439 GLY E CA  1 
ATOM   11368 C C   . GLY D 2 423 ? 171.406 142.657 172.554 1.00 36.90  ? 439 GLY E C   1 
ATOM   11369 O O   . GLY D 2 423 ? 170.336 143.214 172.816 1.00 37.49  ? 439 GLY E O   1 
ATOM   11370 N N   . ARG D 2 424 ? 171.663 141.384 172.847 1.00 40.31  ? 440 ARG E N   1 
ATOM   11371 C CA  . ARG D 2 424 ? 170.680 140.516 173.479 1.00 45.31  ? 440 ARG E CA  1 
ATOM   11372 C C   . ARG D 2 424 ? 170.933 140.473 174.980 1.00 45.93  ? 440 ARG E C   1 
ATOM   11373 O O   . ARG D 2 424 ? 172.054 140.196 175.418 1.00 44.89  ? 440 ARG E O   1 
ATOM   11374 C CB  . ARG D 2 424 ? 170.745 139.109 172.884 1.00 50.59  ? 440 ARG E CB  1 
ATOM   11375 C CG  . ARG D 2 424 ? 169.766 138.121 173.498 1.00 53.86  ? 440 ARG E CG  1 
ATOM   11376 C CD  . ARG D 2 424 ? 170.448 137.171 174.469 1.00 55.79  ? 440 ARG E CD  1 
ATOM   11377 N NE  . ARG D 2 424 ? 169.478 136.347 175.181 1.00 62.75  ? 440 ARG E NE  1 
ATOM   11378 C CZ  . ARG D 2 424 ? 169.552 136.042 176.469 1.00 59.91  ? 440 ARG E CZ  1 
ATOM   11379 N NH1 . ARG D 2 424 ? 170.553 136.465 177.223 1.00 60.63  ? 440 ARG E NH1 1 
ATOM   11380 N NH2 . ARG D 2 424 ? 168.595 135.298 177.014 1.00 53.45  ? 440 ARG E NH2 1 
ATOM   11381 N N   . MET D 2 425 ? 169.891 140.748 175.763 1.00 44.50  ? 441 MET E N   1 
ATOM   11382 C CA  . MET D 2 425 ? 170.016 140.856 177.208 1.00 41.05  ? 441 MET E CA  1 
ATOM   11383 C C   . MET D 2 425 ? 168.890 140.091 177.887 1.00 41.17  ? 441 MET E C   1 
ATOM   11384 O O   . MET D 2 425 ? 167.881 139.743 177.269 1.00 45.24  ? 441 MET E O   1 
ATOM   11385 C CB  . MET D 2 425 ? 170.001 142.319 177.674 1.00 37.06  ? 441 MET E CB  1 
ATOM   11386 C CG  . MET D 2 425 ? 170.473 143.308 176.632 1.00 32.42  ? 441 MET E CG  1 
ATOM   11387 S SD  . MET D 2 425 ? 170.335 145.016 177.160 1.00 38.42  ? 441 MET E SD  1 
ATOM   11388 C CE  . MET D 2 425 ? 171.147 145.825 175.791 1.00 32.45  ? 441 MET E CE  1 
ATOM   11389 N N   . HIS D 2 426 ? 169.085 139.829 179.176 1.00 37.58  ? 442 HIS E N   1 
ATOM   11390 C CA  . HIS D 2 426 ? 168.084 139.214 180.035 1.00 37.79  ? 442 HIS E CA  1 
ATOM   11391 C C   . HIS D 2 426 ? 167.883 140.100 181.255 1.00 34.83  ? 442 HIS E C   1 
ATOM   11392 O O   . HIS D 2 426 ? 168.857 140.505 181.895 1.00 36.90  ? 442 HIS E O   1 
ATOM   11393 C CB  . HIS D 2 426 ? 168.511 137.808 180.460 1.00 41.33  ? 442 HIS E CB  1 
ATOM   11394 C CG  . HIS D 2 426 ? 167.369 136.912 180.818 1.00 42.10  ? 442 HIS E CG  1 
ATOM   11395 N ND1 . HIS D 2 426 ? 167.344 136.166 181.976 1.00 42.68  ? 442 HIS E ND1 1 
ATOM   11396 C CD2 . HIS D 2 426 ? 166.210 136.643 180.173 1.00 43.10  ? 442 HIS E CD2 1 
ATOM   11397 C CE1 . HIS D 2 426 ? 166.219 135.476 182.029 1.00 43.56  ? 442 HIS E CE1 1 
ATOM   11398 N NE2 . HIS D 2 426 ? 165.513 135.747 180.947 1.00 45.74  ? 442 HIS E NE2 1 
ATOM   11399 N N   . ALA D 2 427 ? 166.627 140.396 181.577 1.00 33.99  ? 443 ALA E N   1 
ATOM   11400 C CA  . ALA D 2 427 ? 166.293 141.314 182.654 1.00 30.03  ? 443 ALA E CA  1 
ATOM   11401 C C   . ALA D 2 427 ? 165.480 140.607 183.730 1.00 30.92  ? 443 ALA E C   1 
ATOM   11402 O O   . ALA D 2 427 ? 164.680 139.713 183.443 1.00 33.60  ? 443 ALA E O   1 
ATOM   11403 C CB  . ALA D 2 427 ? 165.512 142.523 182.131 1.00 25.97  ? 443 ALA E CB  1 
ATOM   11404 N N   . ALA D 2 428 ? 165.698 141.022 184.977 1.00 31.82  ? 444 ALA E N   1 
ATOM   11405 C CA  . ALA D 2 428 ? 164.954 140.515 186.123 1.00 28.57  ? 444 ALA E CA  1 
ATOM   11406 C C   . ALA D 2 428 ? 164.613 141.676 187.043 1.00 26.12  ? 444 ALA E C   1 
ATOM   11407 O O   . ALA D 2 428 ? 165.469 142.519 187.320 1.00 27.78  ? 444 ALA E O   1 
ATOM   11408 C CB  . ALA D 2 428 ? 165.757 139.455 186.883 1.00 28.91  ? 444 ALA E CB  1 
ATOM   11409 N N   . VAL D 2 429 ? 163.372 141.717 187.515 1.00 25.53  ? 445 VAL E N   1 
ATOM   11410 C CA  . VAL D 2 429 ? 162.918 142.769 188.418 1.00 26.92  ? 445 VAL E CA  1 
ATOM   11411 C C   . VAL D 2 429 ? 163.133 142.303 189.851 1.00 28.09  ? 445 VAL E C   1 
ATOM   11412 O O   . VAL D 2 429 ? 162.594 141.272 190.266 1.00 32.09  ? 445 VAL E O   1 
ATOM   11413 C CB  . VAL D 2 429 ? 161.445 143.124 188.168 1.00 25.86  ? 445 VAL E CB  1 
ATOM   11414 C CG1 . VAL D 2 429 ? 160.939 144.060 189.248 1.00 23.41  ? 445 VAL E CG1 1 
ATOM   11415 C CG2 . VAL D 2 429 ? 161.280 143.755 186.800 1.00 27.78  ? 445 VAL E CG2 1 
ATOM   11416 N N   . HIS D 2 430 ? 163.916 143.067 190.609 1.00 26.11  ? 446 HIS E N   1 
ATOM   11417 C CA  . HIS D 2 430 ? 164.253 142.725 191.988 1.00 24.67  ? 446 HIS E CA  1 
ATOM   11418 C C   . HIS D 2 430 ? 164.139 143.983 192.835 1.00 29.26  ? 446 HIS E C   1 
ATOM   11419 O O   . HIS D 2 430 ? 165.007 144.856 192.760 1.00 33.70  ? 446 HIS E O   1 
ATOM   11420 C CB  . HIS D 2 430 ? 165.661 142.138 192.079 1.00 28.95  ? 446 HIS E CB  1 
ATOM   11421 C CG  . HIS D 2 430 ? 166.068 141.743 193.464 1.00 34.86  ? 446 HIS E CG  1 
ATOM   11422 N ND1 . HIS D 2 430 ? 167.206 142.227 194.070 1.00 33.55  ? 446 HIS E ND1 1 
ATOM   11423 C CD2 . HIS D 2 430 ? 165.497 140.901 194.357 1.00 39.26  ? 446 HIS E CD2 1 
ATOM   11424 C CE1 . HIS D 2 430 ? 167.314 141.708 195.279 1.00 33.04  ? 446 HIS E CE1 1 
ATOM   11425 N NE2 . HIS D 2 430 ? 166.290 140.899 195.478 1.00 36.14  ? 446 HIS E NE2 1 
ATOM   11426 N N   . LYS D 2 431 ? 163.074 144.076 193.635 1.00 29.90  ? 447 LYS E N   1 
ATOM   11427 C CA  . LYS D 2 431 ? 162.887 145.161 194.599 1.00 30.01  ? 447 LYS E CA  1 
ATOM   11428 C C   . LYS D 2 431 ? 162.908 146.525 193.901 1.00 27.71  ? 447 LYS E C   1 
ATOM   11429 O O   . LYS D 2 431 ? 163.827 147.327 194.061 1.00 29.15  ? 447 LYS E O   1 
ATOM   11430 C CB  . LYS D 2 431 ? 163.943 145.093 195.709 1.00 27.69  ? 447 LYS E CB  1 
ATOM   11431 C CG  . LYS D 2 431 ? 163.488 144.352 196.949 1.00 26.39  ? 447 LYS E CG  1 
ATOM   11432 C CD  . LYS D 2 431 ? 164.647 143.640 197.615 1.00 32.74  ? 447 LYS E CD  1 
ATOM   11433 C CE  . LYS D 2 431 ? 164.163 142.699 198.699 1.00 40.30  ? 447 LYS E CE  1 
ATOM   11434 N NZ  . LYS D 2 431 ? 163.089 141.798 198.205 1.00 49.66  ? 447 LYS E NZ  1 
ATOM   11435 N N   . ASP D 2 432 ? 161.876 146.735 193.081 1.00 25.02  ? 448 ASP E N   1 
ATOM   11436 C CA  . ASP D 2 432 ? 161.648 147.970 192.319 1.00 26.49  ? 448 ASP E CA  1 
ATOM   11437 C C   . ASP D 2 432 ? 162.870 148.391 191.501 1.00 28.19  ? 448 ASP E C   1 
ATOM   11438 O O   . ASP D 2 432 ? 163.014 149.564 191.143 1.00 26.77  ? 448 ASP E O   1 
ATOM   11439 C CB  . ASP D 2 432 ? 161.163 149.119 193.224 1.00 31.96  ? 448 ASP E CB  1 
ATOM   11440 C CG  . ASP D 2 432 ? 162.264 149.718 194.097 1.00 32.02  ? 448 ASP E CG  1 
ATOM   11441 O OD1 . ASP D 2 432 ? 162.959 150.651 193.645 1.00 31.60  ? 448 ASP E OD1 1 
ATOM   11442 O OD2 . ASP D 2 432 ? 162.409 149.280 195.257 1.00 28.97  ? 448 ASP E OD2 1 
ATOM   11443 N N   . LEU D 2 433 ? 163.736 147.439 191.166 1.00 28.30  ? 449 LEU E N   1 
ATOM   11444 C CA  . LEU D 2 433 ? 164.898 147.681 190.325 1.00 25.13  ? 449 LEU E CA  1 
ATOM   11445 C C   . LEU D 2 433 ? 164.973 146.598 189.261 1.00 23.81  ? 449 LEU E C   1 
ATOM   11446 O O   . LEU D 2 433 ? 164.535 145.467 189.478 1.00 26.04  ? 449 LEU E O   1 
ATOM   11447 C CB  . LEU D 2 433 ? 166.198 147.702 191.145 1.00 23.87  ? 449 LEU E CB  1 
ATOM   11448 C CG  . LEU D 2 433 ? 166.320 148.768 192.235 1.00 23.58  ? 449 LEU E CG  1 
ATOM   11449 C CD1 . LEU D 2 433 ? 167.569 148.546 193.062 1.00 22.24  ? 449 LEU E CD1 1 
ATOM   11450 C CD2 . LEU D 2 433 ? 166.320 150.155 191.630 1.00 22.09  ? 449 LEU E CD2 1 
ATOM   11451 N N   . VAL D 2 434 ? 165.534 146.949 188.109 1.00 24.45  ? 450 VAL E N   1 
ATOM   11452 C CA  . VAL D 2 434 ? 165.683 146.025 186.990 1.00 23.65  ? 450 VAL E CA  1 
ATOM   11453 C C   . VAL D 2 434 ? 167.156 145.670 186.861 1.00 25.52  ? 450 VAL E C   1 
ATOM   11454 O O   . VAL D 2 434 ? 168.000 146.551 186.656 1.00 26.08  ? 450 VAL E O   1 
ATOM   11455 C CB  . VAL D 2 434 ? 165.144 146.621 185.681 1.00 22.71  ? 450 VAL E CB  1 
ATOM   11456 C CG1 . VAL D 2 434 ? 164.982 145.535 184.637 1.00 23.38  ? 450 VAL E CG1 1 
ATOM   11457 C CG2 . VAL D 2 434 ? 163.823 147.329 185.921 1.00 23.80  ? 450 VAL E CG2 1 
ATOM   11458 N N   . PHE D 2 435 ? 167.464 144.382 186.977 1.00 25.34  ? 451 PHE E N   1 
ATOM   11459 C CA  . PHE D 2 435 ? 168.820 143.876 186.818 1.00 23.51  ? 451 PHE E CA  1 
ATOM   11460 C C   . PHE D 2 435 ? 168.962 143.308 185.413 1.00 26.75  ? 451 PHE E C   1 
ATOM   11461 O O   . PHE D 2 435 ? 168.218 142.401 185.030 1.00 28.25  ? 451 PHE E O   1 
ATOM   11462 C CB  . PHE D 2 435 ? 169.130 142.809 187.865 1.00 25.66  ? 451 PHE E CB  1 
ATOM   11463 C CG  . PHE D 2 435 ? 169.420 143.363 189.227 1.00 27.64  ? 451 PHE E CG  1 
ATOM   11464 C CD1 . PHE D 2 435 ? 168.394 143.803 190.042 1.00 27.62  ? 451 PHE E CD1 1 
ATOM   11465 C CD2 . PHE D 2 435 ? 170.718 143.441 189.694 1.00 31.22  ? 451 PHE E CD2 1 
ATOM   11466 C CE1 . PHE D 2 435 ? 168.657 144.312 191.293 1.00 26.99  ? 451 PHE E CE1 1 
ATOM   11467 C CE2 . PHE D 2 435 ? 170.986 143.949 190.946 1.00 33.98  ? 451 PHE E CE2 1 
ATOM   11468 C CZ  . PHE D 2 435 ? 169.954 144.385 191.746 1.00 28.46  ? 451 PHE E CZ  1 
ATOM   11469 N N   . ILE D 2 436 ? 169.916 143.836 184.652 1.00 29.54  ? 452 ILE E N   1 
ATOM   11470 C CA  . ILE D 2 436 ? 170.099 143.484 183.250 1.00 26.96  ? 452 ILE E CA  1 
ATOM   11471 C C   . ILE D 2 436 ? 171.485 142.882 183.078 1.00 31.29  ? 452 ILE E C   1 
ATOM   11472 O O   . ILE D 2 436 ? 172.476 143.446 183.554 1.00 34.27  ? 452 ILE E O   1 
ATOM   11473 C CB  . ILE D 2 436 ? 169.914 144.704 182.329 1.00 25.01  ? 452 ILE E CB  1 
ATOM   11474 C CG1 . ILE D 2 436 ? 168.758 145.572 182.822 1.00 22.89  ? 452 ILE E CG1 1 
ATOM   11475 C CG2 . ILE D 2 436 ? 169.665 144.257 180.902 1.00 27.90  ? 452 ILE E CG2 1 
ATOM   11476 C CD1 . ILE D 2 436 ? 168.862 147.015 182.419 1.00 21.22  ? 452 ILE E CD1 1 
ATOM   11477 N N   . VAL D 2 437 ? 171.550 141.741 182.402 1.00 36.55  ? 453 VAL E N   1 
ATOM   11478 C CA  . VAL D 2 437 ? 172.802 141.061 182.107 1.00 39.87  ? 453 VAL E CA  1 
ATOM   11479 C C   . VAL D 2 437 ? 172.903 140.885 180.599 1.00 41.25  ? 453 VAL E C   1 
ATOM   11480 O O   . VAL D 2 437 ? 171.897 140.912 179.884 1.00 41.19  ? 453 VAL E O   1 
ATOM   11481 C CB  . VAL D 2 437 ? 172.903 139.702 182.838 1.00 36.69  ? 453 VAL E CB  1 
ATOM   11482 C CG1 . VAL D 2 437 ? 172.127 138.630 182.095 1.00 37.15  ? 453 VAL E CG1 1 
ATOM   11483 C CG2 . VAL D 2 437 ? 174.354 139.292 183.021 1.00 39.45  ? 453 VAL E CG2 1 
ATOM   11484 N N   . ALA D 2 438 ? 174.128 140.726 180.115 1.00 42.55  ? 454 ALA E N   1 
ATOM   11485 C CA  . ALA D 2 438 ? 174.383 140.533 178.694 1.00 43.52  ? 454 ALA E CA  1 
ATOM   11486 C C   . ALA D 2 438 ? 175.728 139.832 178.548 1.00 54.95  ? 454 ALA E C   1 
ATOM   11487 O O   . ALA D 2 438 ? 176.322 139.382 179.534 1.00 62.41  ? 454 ALA E O   1 
ATOM   11488 C CB  . ALA D 2 438 ? 174.342 141.869 177.944 1.00 42.77  ? 454 ALA E CB  1 
ATOM   11489 N N   . GLU D 2 439 ? 176.210 139.732 177.313 1.00 60.79  ? 455 GLU E N   1 
ATOM   11490 C CA  . GLU D 2 439 ? 177.527 139.160 177.076 1.00 65.05  ? 455 GLU E CA  1 
ATOM   11491 C C   . GLU D 2 439 ? 178.614 140.135 177.510 1.00 69.01  ? 455 GLU E C   1 
ATOM   11492 O O   . GLU D 2 439 ? 178.558 141.330 177.208 1.00 69.06  ? 455 GLU E O   1 
ATOM   11493 C CB  . GLU D 2 439 ? 177.694 138.800 175.600 1.00 63.65  ? 455 GLU E CB  1 
ATOM   11494 C CG  . GLU D 2 439 ? 177.397 139.938 174.635 1.00 62.33  ? 455 GLU E CG  1 
ATOM   11495 C CD  . GLU D 2 439 ? 175.960 139.936 174.154 1.00 61.12  ? 455 GLU E CD  1 
ATOM   11496 O OE1 . GLU D 2 439 ? 175.348 138.848 174.119 1.00 65.89  ? 455 GLU E OE1 1 
ATOM   11497 O OE2 . GLU D 2 439 ? 175.443 141.020 173.813 1.00 53.59  ? 455 GLU E OE2 1 
ATOM   11498 N N   . GLY D 2 440 ? 179.608 139.620 178.228 1.00 71.59  ? 456 GLY E N   1 
ATOM   11499 C CA  . GLY D 2 440 ? 180.706 140.449 178.683 1.00 79.41  ? 456 GLY E CA  1 
ATOM   11500 C C   . GLY D 2 440 ? 180.920 140.421 180.182 1.00 84.48  ? 456 GLY E C   1 
ATOM   11501 O O   . GLY D 2 440 ? 181.774 141.145 180.704 1.00 83.24  ? 456 GLY E O   1 
ATOM   11502 N N   . ASP D 2 441 ? 180.151 139.584 180.881 1.00 85.59  ? 457 ASP E N   1 
ATOM   11503 C CA  . ASP D 2 441 ? 180.279 139.410 182.329 1.00 87.24  ? 457 ASP E CA  1 
ATOM   11504 C C   . ASP D 2 441 ? 180.150 140.740 183.070 1.00 83.70  ? 457 ASP E C   1 
ATOM   11505 O O   . ASP D 2 441 ? 180.899 141.028 184.005 1.00 82.51  ? 457 ASP E O   1 
ATOM   11506 C CB  . ASP D 2 441 ? 181.592 138.711 182.687 1.00 97.13  ? 457 ASP E CB  1 
ATOM   11507 C CG  . ASP D 2 441 ? 181.444 137.205 182.771 1.00 101.90 ? 457 ASP E CG  1 
ATOM   11508 O OD1 . ASP D 2 441 ? 180.306 136.710 182.630 1.00 95.19  ? 457 ASP E OD1 1 
ATOM   11509 O OD2 . ASP D 2 441 ? 182.464 136.515 182.978 1.00 108.43 ? 457 ASP E OD2 1 
ATOM   11510 N N   . SER D 2 442 ? 179.192 141.558 182.644 1.00 80.02  ? 458 SER E N   1 
ATOM   11511 C CA  . SER D 2 442 ? 178.863 142.812 183.306 1.00 69.38  ? 458 SER E CA  1 
ATOM   11512 C C   . SER D 2 442 ? 177.379 142.815 183.637 1.00 60.87  ? 458 SER E C   1 
ATOM   11513 O O   . SER D 2 442 ? 176.547 142.515 182.776 1.00 57.50  ? 458 SER E O   1 
ATOM   11514 C CB  . SER D 2 442 ? 179.214 144.015 182.426 1.00 68.48  ? 458 SER E CB  1 
ATOM   11515 O OG  . SER D 2 442 ? 179.436 145.173 183.211 1.00 62.80  ? 458 SER E OG  1 
ATOM   11516 N N   . LEU D 2 443 ? 177.053 143.154 184.880 1.00 55.89  ? 459 LEU E N   1 
ATOM   11517 C CA  . LEU D 2 443 ? 175.678 143.197 185.356 1.00 47.06  ? 459 LEU E CA  1 
ATOM   11518 C C   . LEU D 2 443 ? 175.309 144.636 185.684 1.00 42.48  ? 459 LEU E C   1 
ATOM   11519 O O   . LEU D 2 443 ? 176.076 145.342 186.344 1.00 47.23  ? 459 LEU E O   1 
ATOM   11520 C CB  . LEU D 2 443 ? 175.495 142.304 186.582 1.00 44.68  ? 459 LEU E CB  1 
ATOM   11521 C CG  . LEU D 2 443 ? 174.067 142.179 187.106 1.00 41.42  ? 459 LEU E CG  1 
ATOM   11522 C CD1 . LEU D 2 443 ? 173.373 141.005 186.454 1.00 43.37  ? 459 LEU E CD1 1 
ATOM   11523 C CD2 . LEU D 2 443 ? 174.071 142.023 188.608 1.00 45.71  ? 459 LEU E CD2 1 
ATOM   11524 N N   . VAL D 2 444 ? 174.137 145.064 185.224 1.00 36.52  ? 460 VAL E N   1 
ATOM   11525 C CA  . VAL D 2 444 ? 173.698 146.449 185.334 1.00 31.38  ? 460 VAL E CA  1 
ATOM   11526 C C   . VAL D 2 444 ? 172.394 146.488 186.117 1.00 30.20  ? 460 VAL E C   1 
ATOM   11527 O O   . VAL D 2 444 ? 171.467 145.724 185.829 1.00 31.55  ? 460 VAL E O   1 
ATOM   11528 C CB  . VAL D 2 444 ? 173.529 147.093 183.945 1.00 27.40  ? 460 VAL E CB  1 
ATOM   11529 C CG1 . VAL D 2 444 ? 172.477 148.184 183.973 1.00 23.69  ? 460 VAL E CG1 1 
ATOM   11530 C CG2 . VAL D 2 444 ? 174.855 147.642 183.461 1.00 31.53  ? 460 VAL E CG2 1 
ATOM   11531 N N   . CYS D 2 445 ? 172.332 147.366 187.113 1.00 30.46  ? 461 CYS E N   1 
ATOM   11532 C CA  . CYS D 2 445 ? 171.115 147.617 187.871 1.00 25.40  ? 461 CYS E CA  1 
ATOM   11533 C C   . CYS D 2 445 ? 170.504 148.930 187.404 1.00 26.80  ? 461 CYS E C   1 
ATOM   11534 O O   . CYS D 2 445 ? 171.193 149.952 187.340 1.00 28.00  ? 461 CYS E O   1 
ATOM   11535 C CB  . CYS D 2 445 ? 171.399 147.666 189.371 1.00 23.80  ? 461 CYS E CB  1 
ATOM   11536 S SG  . CYS D 2 445 ? 169.928 147.840 190.395 1.00 27.75  ? 461 CYS E SG  1 
ATOM   11537 N N   . TYR D 2 446 ? 169.218 148.897 187.078 1.00 25.55  ? 462 TYR E N   1 
ATOM   11538 C CA  . TYR D 2 446 ? 168.520 150.032 186.494 1.00 20.51  ? 462 TYR E CA  1 
ATOM   11539 C C   . TYR D 2 446 ? 167.469 150.543 187.470 1.00 21.90  ? 462 TYR E C   1 
ATOM   11540 O O   . TYR D 2 446 ? 166.636 149.771 187.953 1.00 19.74  ? 462 TYR E O   1 
ATOM   11541 C CB  . TYR D 2 446 ? 167.876 149.634 185.164 1.00 20.18  ? 462 TYR E CB  1 
ATOM   11542 C CG  . TYR D 2 446 ? 167.147 150.747 184.449 1.00 22.52  ? 462 TYR E CG  1 
ATOM   11543 C CD1 . TYR D 2 446 ? 167.625 152.049 184.474 1.00 22.64  ? 462 TYR E CD1 1 
ATOM   11544 C CD2 . TYR D 2 446 ? 165.983 150.491 183.739 1.00 19.75  ? 462 TYR E CD2 1 
ATOM   11545 C CE1 . TYR D 2 446 ? 166.961 153.064 183.820 1.00 22.46  ? 462 TYR E CE1 1 
ATOM   11546 C CE2 . TYR D 2 446 ? 165.314 151.498 183.082 1.00 19.13  ? 462 TYR E CE2 1 
ATOM   11547 C CZ  . TYR D 2 446 ? 165.807 152.782 183.125 1.00 21.97  ? 462 TYR E CZ  1 
ATOM   11548 O OH  . TYR D 2 446 ? 165.140 153.789 182.471 1.00 32.12  ? 462 TYR E OH  1 
ATOM   11549 N N   . ASN D 2 447 ? 167.518 151.844 187.759 1.00 24.14  ? 463 ASN E N   1 
ATOM   11550 C CA  . ASN D 2 447 ? 166.542 152.519 188.609 1.00 22.58  ? 463 ASN E CA  1 
ATOM   11551 C C   . ASN D 2 447 ? 165.733 153.460 187.729 1.00 24.18  ? 463 ASN E C   1 
ATOM   11552 O O   . ASN D 2 447 ? 166.145 154.604 187.491 1.00 28.37  ? 463 ASN E O   1 
ATOM   11553 C CB  . ASN D 2 447 ? 167.234 153.286 189.738 1.00 23.70  ? 463 ASN E CB  1 
ATOM   11554 C CG  . ASN D 2 447 ? 166.309 153.577 190.902 1.00 23.89  ? 463 ASN E CG  1 
ATOM   11555 O OD1 . ASN D 2 447 ? 165.093 153.641 190.741 1.00 29.52  ? 463 ASN E OD1 1 
ATOM   11556 N ND2 . ASN D 2 447 ? 166.883 153.748 192.085 1.00 22.23  ? 463 ASN E ND2 1 
ATOM   11557 N N   . PRO D 2 448 ? 164.585 153.023 187.206 1.00 22.49  ? 464 PRO E N   1 
ATOM   11558 C CA  . PRO D 2 448 ? 163.824 153.885 186.288 1.00 24.47  ? 464 PRO E CA  1 
ATOM   11559 C C   . PRO D 2 448 ? 163.362 155.189 186.912 1.00 33.90  ? 464 PRO E C   1 
ATOM   11560 O O   . PRO D 2 448 ? 163.272 156.201 186.205 1.00 36.47  ? 464 PRO E O   1 
ATOM   11561 C CB  . PRO D 2 448 ? 162.638 153.000 185.883 1.00 24.40  ? 464 PRO E CB  1 
ATOM   11562 C CG  . PRO D 2 448 ? 163.068 151.606 186.187 1.00 21.99  ? 464 PRO E CG  1 
ATOM   11563 C CD  . PRO D 2 448 ? 163.954 151.705 187.377 1.00 22.45  ? 464 PRO E CD  1 
ATOM   11564 N N   . LEU D 2 449 ? 163.055 155.197 188.212 1.00 34.17  ? 465 LEU E N   1 
ATOM   11565 C CA  . LEU D 2 449 ? 162.581 156.419 188.854 1.00 32.35  ? 465 LEU E CA  1 
ATOM   11566 C C   . LEU D 2 449 ? 163.654 157.500 188.858 1.00 33.75  ? 465 LEU E C   1 
ATOM   11567 O O   . LEU D 2 449 ? 163.363 158.671 188.587 1.00 40.27  ? 465 LEU E O   1 
ATOM   11568 C CB  . LEU D 2 449 ? 162.116 156.118 190.278 1.00 33.87  ? 465 LEU E CB  1 
ATOM   11569 C CG  . LEU D 2 449 ? 160.674 155.630 190.433 1.00 38.53  ? 465 LEU E CG  1 
ATOM   11570 C CD1 . LEU D 2 449 ? 160.206 155.790 191.869 1.00 32.61  ? 465 LEU E CD1 1 
ATOM   11571 C CD2 . LEU D 2 449 ? 159.744 156.364 189.481 1.00 37.93  ? 465 LEU E CD2 1 
ATOM   11572 N N   . LEU D 2 450 ? 164.897 157.134 189.165 1.00 31.50  ? 466 LEU E N   1 
ATOM   11573 C CA  . LEU D 2 450 ? 166.002 158.081 189.137 1.00 34.65  ? 466 LEU E CA  1 
ATOM   11574 C C   . LEU D 2 450 ? 166.709 158.134 187.789 1.00 37.59  ? 466 LEU E C   1 
ATOM   11575 O O   . LEU D 2 450 ? 167.592 158.978 187.609 1.00 39.25  ? 466 LEU E O   1 
ATOM   11576 C CB  . LEU D 2 450 ? 167.021 157.745 190.230 1.00 33.34  ? 466 LEU E CB  1 
ATOM   11577 C CG  . LEU D 2 450 ? 166.497 157.634 191.663 1.00 34.69  ? 466 LEU E CG  1 
ATOM   11578 C CD1 . LEU D 2 450 ? 167.586 157.124 192.589 1.00 32.69  ? 466 LEU E CD1 1 
ATOM   11579 C CD2 . LEU D 2 450 ? 165.964 158.970 192.148 1.00 34.92  ? 466 LEU E CD2 1 
ATOM   11580 N N   . ASP D 2 451 ? 166.340 157.260 186.849 1.00 36.16  ? 467 ASP E N   1 
ATOM   11581 C CA  . ASP D 2 451 ? 166.909 157.241 185.500 1.00 35.12  ? 467 ASP E CA  1 
ATOM   11582 C C   . ASP D 2 451 ? 168.428 157.080 185.533 1.00 37.12  ? 467 ASP E C   1 
ATOM   11583 O O   . ASP D 2 451 ? 169.164 157.762 184.818 1.00 38.32  ? 467 ASP E O   1 
ATOM   11584 C CB  . ASP D 2 451 ? 166.512 158.498 184.722 1.00 40.96  ? 467 ASP E CB  1 
ATOM   11585 C CG  . ASP D 2 451 ? 165.026 158.565 184.442 1.00 49.91  ? 467 ASP E CG  1 
ATOM   11586 O OD1 . ASP D 2 451 ? 164.500 157.641 183.787 1.00 49.52  ? 467 ASP E OD1 1 
ATOM   11587 O OD2 . ASP D 2 451 ? 164.383 159.543 184.875 1.00 52.68  ? 467 ASP E OD2 1 
ATOM   11588 N N   . SER D 2 452 ? 168.899 156.155 186.367 1.00 32.95  ? 468 SER E N   1 
ATOM   11589 C CA  . SER D 2 452 ? 170.327 155.961 186.566 1.00 31.29  ? 468 SER E CA  1 
ATOM   11590 C C   . SER D 2 452 ? 170.656 154.475 186.544 1.00 26.11  ? 468 SER E C   1 
ATOM   11591 O O   . SER D 2 452 ? 169.804 153.624 186.800 1.00 26.76  ? 468 SER E O   1 
ATOM   11592 C CB  . SER D 2 452 ? 170.799 156.589 187.885 1.00 34.76  ? 468 SER E CB  1 
ATOM   11593 O OG  . SER D 2 452 ? 169.938 156.240 188.955 1.00 31.14  ? 468 SER E OG  1 
ATOM   11594 N N   . PHE D 2 453 ? 171.915 154.177 186.229 1.00 28.23  ? 469 PHE E N   1 
ATOM   11595 C CA  . PHE D 2 453 ? 172.432 152.818 186.194 1.00 30.13  ? 469 PHE E CA  1 
ATOM   11596 C C   . PHE D 2 453 ? 173.574 152.672 187.190 1.00 31.20  ? 469 PHE E C   1 
ATOM   11597 O O   . PHE D 2 453 ? 174.265 153.641 187.514 1.00 34.11  ? 469 PHE E O   1 
ATOM   11598 C CB  . PHE D 2 453 ? 172.948 152.435 184.794 1.00 28.42  ? 469 PHE E CB  1 
ATOM   11599 C CG  . PHE D 2 453 ? 171.924 152.556 183.702 1.00 27.62  ? 469 PHE E CG  1 
ATOM   11600 C CD1 . PHE D 2 453 ? 171.754 153.749 183.025 1.00 28.24  ? 469 PHE E CD1 1 
ATOM   11601 C CD2 . PHE D 2 453 ? 171.153 151.469 183.332 1.00 29.45  ? 469 PHE E CD2 1 
ATOM   11602 C CE1 . PHE D 2 453 ? 170.822 153.861 182.017 1.00 31.01  ? 469 PHE E CE1 1 
ATOM   11603 C CE2 . PHE D 2 453 ? 170.222 151.576 182.322 1.00 26.39  ? 469 PHE E CE2 1 
ATOM   11604 C CZ  . PHE D 2 453 ? 170.056 152.773 181.665 1.00 31.15  ? 469 PHE E CZ  1 
ATOM   11605 N N   . THR D 2 454 ? 173.753 151.443 187.659 1.00 29.11  ? 470 THR E N   1 
ATOM   11606 C CA  . THR D 2 454 ? 174.906 151.100 188.491 1.00 33.26  ? 470 THR E CA  1 
ATOM   11607 C C   . THR D 2 454 ? 175.371 149.822 187.861 1.00 36.88  ? 470 THR E C   1 
ATOM   11608 O O   . THR D 2 454 ? 174.557 149.202 187.216 1.00 37.84  ? 470 THR E O   1 
ATOM   11609 C CB  . THR D 2 454 ? 174.621 150.973 189.989 1.00 34.41  ? 470 THR E CB  1 
ATOM   11610 O OG1 . THR D 2 454 ? 173.788 149.843 190.216 1.00 38.08  ? 470 THR E OG1 1 
ATOM   11611 C CG2 . THR D 2 454 ? 173.965 152.213 190.569 1.00 33.28  ? 470 THR E CG2 1 
ATOM   11612 N N   . ARG D 2 455 ? 176.644 149.477 187.958 1.00 43.18  ? 471 ARG E N   1 
ATOM   11613 C CA  . ARG D 2 455 ? 177.166 148.292 187.242 1.00 45.73  ? 471 ARG E CA  1 
ATOM   11614 C C   . ARG D 2 455 ? 178.048 147.449 188.156 1.00 51.13  ? 471 ARG E C   1 
ATOM   11615 O O   . ARG D 2 455 ? 178.975 148.018 188.748 1.00 53.66  ? 471 ARG E O   1 
ATOM   11616 C CB  . ARG D 2 455 ? 178.079 148.666 186.071 1.00 47.35  ? 471 ARG E CB  1 
ATOM   11617 C CG  . ARG D 2 455 ? 177.443 149.545 185.004 1.00 48.30  ? 471 ARG E CG  1 
ATOM   11618 C CD  . ARG D 2 455 ? 178.141 150.878 184.782 1.00 53.26  ? 471 ARG E CD  1 
ATOM   11619 N NE  . ARG D 2 455 ? 177.267 152.037 185.000 1.00 51.10  ? 471 ARG E NE  1 
ATOM   11620 C CZ  . ARG D 2 455 ? 177.577 153.077 185.767 1.00 48.45  ? 471 ARG E CZ  1 
ATOM   11621 N NH1 . ARG D 2 455 ? 178.201 152.902 186.919 1.00 46.86  ? 471 ARG E NH1 1 
ATOM   11622 N NH2 . ARG D 2 455 ? 177.260 154.295 185.376 1.00 43.91  ? 471 ARG E NH2 1 
ATOM   11623 N N   . LEU D 2 456 ? 177.757 146.156 188.284 1.00 54.88  ? 472 LEU E N   1 
ATOM   11624 C CA  . LEU D 2 456 ? 178.647 145.233 189.027 1.00 59.59  ? 472 LEU E CA  1 
ATOM   11625 C C   . LEU D 2 456 ? 179.421 144.428 187.977 1.00 66.74  ? 472 LEU E C   1 
ATOM   11626 O O   . LEU D 2 456 ? 178.877 144.223 186.881 1.00 66.84  ? 472 LEU E O   1 
ATOM   11627 C CB  . LEU D 2 456 ? 177.842 144.306 189.929 1.00 55.65  ? 472 LEU E CB  1 
ATOM   11628 C CG  . LEU D 2 456 ? 178.375 142.879 190.084 1.00 61.17  ? 472 LEU E CG  1 
ATOM   11629 C CD1 . LEU D 2 456 ? 179.291 142.748 191.283 1.00 64.50  ? 472 LEU E CD1 1 
ATOM   11630 C CD2 . LEU D 2 456 ? 177.260 141.864 190.153 1.00 66.88  ? 472 LEU E CD2 1 
ATOM   11631 N N   . CYS D 2 457 ? 180.653 144.020 188.273 1.00 74.48  ? 473 CYS E N   1 
ATOM   11632 C CA  . CYS D 2 457 ? 181.419 143.161 187.337 1.00 78.43  ? 473 CYS E CA  1 
ATOM   11633 C C   . CYS D 2 457 ? 181.297 141.694 187.779 1.00 80.88  ? 473 CYS E C   1 
ATOM   11634 O O   . CYS D 2 457 ? 181.856 141.351 188.836 1.00 80.93  ? 473 CYS E O   1 
ATOM   11635 C CB  . CYS D 2 457 ? 182.871 143.607 187.279 1.00 80.22  ? 473 CYS E CB  1 
ATOM   11636 S SG  . CYS D 2 457 ? 183.119 145.052 186.217 1.00 88.02  ? 473 CYS E SG  1 
ATOM   11637 N N   . LEU D 2 458 ? 180.589 140.873 187.001 1.00 83.18  ? 474 LEU E N   1 
ATOM   11638 C CA  . LEU D 2 458 ? 180.379 139.449 187.352 1.00 86.08  ? 474 LEU E CA  1 
ATOM   11639 C C   . LEU D 2 458 ? 181.717 138.709 187.228 1.00 94.56  ? 474 LEU E C   1 
ATOM   11640 O O   . LEU D 2 458 ? 182.588 139.211 186.500 1.00 98.74  ? 474 LEU E O   1 
ATOM   11641 C CB  . LEU D 2 458 ? 179.326 138.905 186.392 1.00 84.69  ? 474 LEU E CB  1 
ATOM   11642 C CG  . LEU D 2 458 ? 177.866 139.190 186.743 1.00 73.67  ? 474 LEU E CG  1 
ATOM   11643 C CD1 . LEU D 2 458 ? 176.983 138.597 185.665 1.00 68.50  ? 474 LEU E CD1 1 
ATOM   11644 C CD2 . LEU D 2 458 ? 177.551 138.575 188.090 1.00 71.60  ? 474 LEU E CD2 1 
ATOM   11645 N N   . PRO D 2 459 ? 181.920 137.530 187.861 1.00 99.06  ? 475 PRO E N   1 
ATOM   11646 C CA  . PRO D 2 459 ? 183.223 136.850 187.833 1.00 103.02 ? 475 PRO E CA  1 
ATOM   11647 C C   . PRO D 2 459 ? 183.662 136.492 186.422 1.00 107.64 ? 475 PRO E C   1 
ATOM   11648 O O   . PRO D 2 459 ? 183.052 135.646 185.761 1.00 106.88 ? 475 PRO E O   1 
ATOM   11649 C CB  . PRO D 2 459 ? 182.987 135.603 188.694 1.00 101.79 ? 475 PRO E CB  1 
ATOM   11650 C CG  . PRO D 2 459 ? 181.534 135.335 188.572 1.00 94.92  ? 475 PRO E CG  1 
ATOM   11651 C CD  . PRO D 2 459 ? 180.876 136.685 188.472 1.00 95.68  ? 475 PRO E CD  1 
ATOM   11652 N N   . GLU D 2 460 ? 184.730 137.141 185.957 1.00 111.01 ? 476 GLU E N   1 
ATOM   11653 C CA  . GLU D 2 460 ? 185.240 136.959 184.606 1.00 114.82 ? 476 GLU E CA  1 
ATOM   11654 C C   . GLU D 2 460 ? 186.261 135.832 184.508 1.00 117.36 ? 476 GLU E C   1 
ATOM   11655 O O   . GLU D 2 460 ? 187.073 135.824 183.576 1.00 116.06 ? 476 GLU E O   1 
ATOM   11656 C CB  . GLU D 2 460 ? 185.848 138.266 184.092 1.00 115.90 ? 476 GLU E CB  1 
ATOM   11657 C CG  . GLU D 2 460 ? 185.220 139.516 184.690 1.00 113.09 ? 476 GLU E CG  1 
ATOM   11658 C CD  . GLU D 2 460 ? 185.417 140.745 183.823 1.00 113.15 ? 476 GLU E CD  1 
ATOM   11659 O OE1 . GLU D 2 460 ? 185.916 140.601 182.688 1.00 116.76 ? 476 GLU E OE1 1 
ATOM   11660 O OE2 . GLU D 2 460 ? 185.066 141.855 184.276 1.00 109.95 ? 476 GLU E OE2 1 
ATOM   11661 N N   . ALA D 2 461 ? 186.243 134.889 185.454 1.00 118.04 ? 477 ALA E N   1 
ATOM   11662 C CA  . ALA D 2 461 ? 187.152 133.751 185.381 1.00 117.64 ? 477 ALA E CA  1 
ATOM   11663 C C   . ALA D 2 461 ? 186.875 132.892 184.155 1.00 122.83 ? 477 ALA E C   1 
ATOM   11664 O O   . ALA D 2 461 ? 187.799 132.290 183.596 1.00 123.45 ? 477 ALA E O   1 
ATOM   11665 C CB  . ALA D 2 461 ? 187.048 132.913 186.654 1.00 111.71 ? 477 ALA E CB  1 
ATOM   11666 N N   . TRP D 2 462 ? 185.616 132.824 183.721 1.00 122.81 ? 478 TRP E N   1 
ATOM   11667 C CA  . TRP D 2 462 ? 185.218 132.079 182.526 1.00 122.91 ? 478 TRP E CA  1 
ATOM   11668 C C   . TRP D 2 462 ? 184.445 133.038 181.625 1.00 122.47 ? 478 TRP E C   1 
ATOM   11669 O O   . TRP D 2 462 ? 183.215 133.109 181.686 1.00 120.83 ? 478 TRP E O   1 
ATOM   11670 C CB  . TRP D 2 462 ? 184.389 130.851 182.891 1.00 121.56 ? 478 TRP E CB  1 
ATOM   11671 C CG  . TRP D 2 462 ? 185.068 129.548 182.592 1.00 121.53 ? 478 TRP E CG  1 
ATOM   11672 C CD1 . TRP D 2 462 ? 185.453 128.600 183.494 1.00 120.63 ? 478 TRP E CD1 1 
ATOM   11673 C CD2 . TRP D 2 462 ? 185.439 129.048 181.301 1.00 123.20 ? 478 TRP E CD2 1 
ATOM   11674 N NE1 . TRP D 2 462 ? 186.042 127.542 182.846 1.00 122.92 ? 478 TRP E NE1 1 
ATOM   11675 C CE2 . TRP D 2 462 ? 186.046 127.792 181.499 1.00 122.91 ? 478 TRP E CE2 1 
ATOM   11676 C CE3 . TRP D 2 462 ? 185.318 129.541 179.998 1.00 122.69 ? 478 TRP E CE3 1 
ATOM   11677 C CZ2 . TRP D 2 462 ? 186.531 127.022 180.444 1.00 121.29 ? 478 TRP E CZ2 1 
ATOM   11678 C CZ3 . TRP D 2 462 ? 185.801 128.774 178.951 1.00 124.09 ? 478 TRP E CZ3 1 
ATOM   11679 C CH2 . TRP D 2 462 ? 186.399 127.529 179.181 1.00 122.60 ? 478 TRP E CH2 1 
ATOM   11680 N N   . SER D 2 463 ? 185.174 133.777 180.786 1.00 123.61 ? 479 SER E N   1 
ATOM   11681 C CA  . SER D 2 463 ? 184.569 134.719 179.857 1.00 124.25 ? 479 SER E CA  1 
ATOM   11682 C C   . SER D 2 463 ? 184.911 134.454 178.399 1.00 125.86 ? 479 SER E C   1 
ATOM   11683 O O   . SER D 2 463 ? 184.246 135.013 177.520 1.00 124.21 ? 479 SER E O   1 
ATOM   11684 C CB  . SER D 2 463 ? 184.983 136.159 180.203 1.00 119.44 ? 479 SER E CB  1 
ATOM   11685 O OG  . SER D 2 463 ? 184.194 137.100 179.496 1.00 112.85 ? 479 SER E OG  1 
ATOM   11686 N N   . SER D 2 464 ? 185.921 133.628 178.116 1.00 126.29 ? 480 SER E N   1 
ATOM   11687 C CA  . SER D 2 464 ? 186.271 133.336 176.730 1.00 126.64 ? 480 SER E CA  1 
ATOM   11688 C C   . SER D 2 464 ? 185.179 132.528 176.041 1.00 125.38 ? 480 SER E C   1 
ATOM   11689 O O   . SER D 2 464 ? 184.982 132.650 174.826 1.00 123.07 ? 480 SER E O   1 
ATOM   11690 C CB  . SER D 2 464 ? 187.606 132.594 176.673 1.00 125.29 ? 480 SER E CB  1 
ATOM   11691 O OG  . SER D 2 464 ? 187.631 131.520 177.597 1.00 126.40 ? 480 SER E OG  1 
ATOM   11692 N N   . ALA D 2 465 ? 184.469 131.697 176.795 1.00 125.82 ? 481 ALA E N   1 
ATOM   11693 C CA  . ALA D 2 465 ? 183.419 130.873 176.215 1.00 123.87 ? 481 ALA E CA  1 
ATOM   11694 C C   . ALA D 2 465 ? 182.279 131.752 175.708 1.00 122.67 ? 481 ALA E C   1 
ATOM   11695 O O   . ALA D 2 465 ? 181.845 132.669 176.419 1.00 120.61 ? 481 ALA E O   1 
ATOM   11696 C CB  . ALA D 2 465 ? 182.894 129.874 177.244 1.00 122.18 ? 481 ALA E CB  1 
ATOM   11697 N N   . PRO D 2 466 ? 181.772 131.513 174.497 1.00 120.27 ? 482 PRO E N   1 
ATOM   11698 C CA  . PRO D 2 466 ? 180.616 132.281 173.986 1.00 117.63 ? 482 PRO E CA  1 
ATOM   11699 C C   . PRO D 2 466 ? 179.303 131.794 174.588 1.00 114.77 ? 482 PRO E C   1 
ATOM   11700 O O   . PRO D 2 466 ? 178.432 131.223 173.923 1.00 113.23 ? 482 PRO E O   1 
ATOM   11701 C CB  . PRO D 2 466 ? 180.706 132.038 172.476 1.00 116.10 ? 482 PRO E CB  1 
ATOM   11702 C CG  . PRO D 2 466 ? 181.298 130.674 172.364 1.00 114.40 ? 482 PRO E CG  1 
ATOM   11703 C CD  . PRO D 2 466 ? 182.264 130.532 173.514 1.00 115.96 ? 482 PRO E CD  1 
ATOM   11704 N N   . SER D 2 467 ? 179.148 132.023 175.888 1.00 112.11 ? 483 SER E N   1 
ATOM   11705 C CA  . SER D 2 467 ? 178.001 131.544 176.643 1.00 106.09 ? 483 SER E CA  1 
ATOM   11706 C C   . SER D 2 467 ? 177.121 132.712 177.064 1.00 100.81 ? 483 SER E C   1 
ATOM   11707 O O   . SER D 2 467 ? 177.620 133.778 177.436 1.00 97.40  ? 483 SER E O   1 
ATOM   11708 C CB  . SER D 2 467 ? 178.448 130.759 177.879 1.00 104.69 ? 483 SER E CB  1 
ATOM   11709 O OG  . SER D 2 467 ? 177.378 130.598 178.794 1.00 99.41  ? 483 SER E OG  1 
ATOM   11710 N N   . LEU D 2 468 ? 175.811 132.502 177.001 1.00 95.10  ? 484 LEU E N   1 
ATOM   11711 C CA  . LEU D 2 468 ? 174.840 133.498 177.422 1.00 87.85  ? 484 LEU E CA  1 
ATOM   11712 C C   . LEU D 2 468 ? 174.578 133.380 178.919 1.00 83.57  ? 484 LEU E C   1 
ATOM   11713 O O   . LEU D 2 468 ? 174.767 132.326 179.529 1.00 84.94  ? 484 LEU E O   1 
ATOM   11714 C CB  . LEU D 2 468 ? 173.531 133.340 176.646 1.00 84.11  ? 484 LEU E CB  1 
ATOM   11715 C CG  . LEU D 2 468 ? 173.556 133.479 175.121 1.00 84.37  ? 484 LEU E CG  1 
ATOM   11716 C CD1 . LEU D 2 468 ? 172.247 134.069 174.634 1.00 78.90  ? 484 LEU E CD1 1 
ATOM   11717 C CD2 . LEU D 2 468 ? 174.722 134.342 174.655 1.00 86.83  ? 484 LEU E CD2 1 
ATOM   11718 N N   . TRP D 2 469 ? 174.140 134.487 179.510 1.00 74.04  ? 485 TRP E N   1 
ATOM   11719 C CA  . TRP D 2 469 ? 173.861 134.556 180.936 1.00 67.14  ? 485 TRP E CA  1 
ATOM   11720 C C   . TRP D 2 469 ? 172.386 134.853 181.156 1.00 65.34  ? 485 TRP E C   1 
ATOM   11721 O O   . TRP D 2 469 ? 171.824 135.755 180.527 1.00 65.65  ? 485 TRP E O   1 
ATOM   11722 C CB  . TRP D 2 469 ? 174.715 135.626 181.617 1.00 65.77  ? 485 TRP E CB  1 
ATOM   11723 C CG  . TRP D 2 469 ? 176.091 135.159 181.963 1.00 75.69  ? 485 TRP E CG  1 
ATOM   11724 C CD1 . TRP D 2 469 ? 177.246 135.463 181.307 1.00 82.32  ? 485 TRP E CD1 1 
ATOM   11725 C CD2 . TRP D 2 469 ? 176.458 134.293 183.043 1.00 75.75  ? 485 TRP E CD2 1 
ATOM   11726 N NE1 . TRP D 2 469 ? 178.311 134.845 181.914 1.00 84.54  ? 485 TRP E NE1 1 
ATOM   11727 C CE2 . TRP D 2 469 ? 177.854 134.120 182.982 1.00 82.37  ? 485 TRP E CE2 1 
ATOM   11728 C CE3 . TRP D 2 469 ? 175.743 133.649 184.054 1.00 72.71  ? 485 TRP E CE3 1 
ATOM   11729 C CZ2 . TRP D 2 469 ? 178.547 133.331 183.895 1.00 84.49  ? 485 TRP E CZ2 1 
ATOM   11730 C CZ3 . TRP D 2 469 ? 176.433 132.867 184.959 1.00 74.10  ? 485 TRP E CZ3 1 
ATOM   11731 C CH2 . TRP D 2 469 ? 177.820 132.714 184.874 1.00 78.97  ? 485 TRP E CH2 1 
ATOM   11732 N N   . LYS D 2 470 ? 171.765 134.089 182.048 1.00 57.96  ? 486 LYS E N   1 
ATOM   11733 C CA  . LYS D 2 470 ? 170.376 134.283 182.425 1.00 50.62  ? 486 LYS E CA  1 
ATOM   11734 C C   . LYS D 2 470 ? 170.308 134.686 183.890 1.00 49.41  ? 486 LYS E C   1 
ATOM   11735 O O   . LYS D 2 470 ? 171.133 134.267 184.704 1.00 52.56  ? 486 LYS E O   1 
ATOM   11736 C CB  . LYS D 2 470 ? 169.549 133.016 182.191 1.00 56.27  ? 486 LYS E CB  1 
ATOM   11737 C CG  . LYS D 2 470 ? 169.854 132.302 180.886 1.00 59.88  ? 486 LYS E CG  1 
ATOM   11738 C CD  . LYS D 2 470 ? 168.715 132.447 179.896 1.00 58.07  ? 486 LYS E CD  1 
ATOM   11739 C CE  . LYS D 2 470 ? 169.228 132.459 178.471 1.00 62.55  ? 486 LYS E CE  1 
ATOM   11740 N NZ  . LYS D 2 470 ? 170.278 131.430 178.254 1.00 72.24  ? 486 LYS E NZ  1 
ATOM   11741 N N   . ILE D 2 471 ? 169.317 135.508 184.219 1.00 45.77  ? 487 ILE E N   1 
ATOM   11742 C CA  . ILE D 2 471 ? 169.187 136.092 185.547 1.00 39.61  ? 487 ILE E CA  1 
ATOM   11743 C C   . ILE D 2 471 ? 167.759 135.893 186.035 1.00 45.24  ? 487 ILE E C   1 
ATOM   11744 O O   . ILE D 2 471 ? 166.803 136.035 185.263 1.00 50.37  ? 487 ILE E O   1 
ATOM   11745 C CB  . ILE D 2 471 ? 169.577 137.587 185.537 1.00 36.50  ? 487 ILE E CB  1 
ATOM   11746 C CG1 . ILE D 2 471 ? 169.344 138.226 186.902 1.00 40.86  ? 487 ILE E CG1 1 
ATOM   11747 C CG2 . ILE D 2 471 ? 168.832 138.340 184.451 1.00 35.50  ? 487 ILE E CG2 1 
ATOM   11748 C CD1 . ILE D 2 471 ? 170.192 139.440 187.132 1.00 39.28  ? 487 ILE E CD1 1 
ATOM   11749 N N   . ALA D 2 472 ? 167.614 135.541 187.311 1.00 42.97  ? 488 ALA E N   1 
ATOM   11750 C CA  . ALA D 2 472 ? 166.299 135.355 187.914 1.00 43.27  ? 488 ALA E CA  1 
ATOM   11751 C C   . ALA D 2 472 ? 166.390 135.679 189.396 1.00 46.04  ? 488 ALA E C   1 
ATOM   11752 O O   . ALA D 2 472 ? 167.189 135.072 190.114 1.00 49.08  ? 488 ALA E O   1 
ATOM   11753 C CB  . ALA D 2 472 ? 165.794 133.928 187.703 1.00 47.09  ? 488 ALA E CB  1 
ATOM   11754 N N   . SER D 2 473 ? 165.576 136.628 189.850 1.00 48.96  ? 489 SER E N   1 
ATOM   11755 C CA  . SER D 2 473 ? 165.608 137.066 191.237 1.00 52.99  ? 489 SER E CA  1 
ATOM   11756 C C   . SER D 2 473 ? 164.816 136.118 192.128 1.00 59.72  ? 489 SER E C   1 
ATOM   11757 O O   . SER D 2 473 ? 163.828 135.513 191.702 1.00 60.22  ? 489 SER E O   1 
ATOM   11758 C CB  . SER D 2 473 ? 165.044 138.480 191.367 1.00 45.81  ? 489 SER E CB  1 
ATOM   11759 O OG  . SER D 2 473 ? 163.832 138.606 190.648 1.00 46.73  ? 489 SER E OG  1 
ATOM   11760 N N   . CYS D 2 474 ? 165.256 135.996 193.380 1.00 67.16  ? 490 CYS E N   1 
ATOM   11761 C CA  . CYS D 2 474 ? 164.554 135.144 194.337 1.00 72.39  ? 490 CYS E CA  1 
ATOM   11762 C C   . CYS D 2 474 ? 164.893 135.587 195.756 1.00 70.19  ? 490 CYS E C   1 
ATOM   11763 O O   . CYS D 2 474 ? 166.016 135.364 196.218 1.00 68.84  ? 490 CYS E O   1 
ATOM   11764 C CB  . CYS D 2 474 ? 164.917 133.681 194.121 1.00 71.22  ? 490 CYS E CB  1 
ATOM   11765 S SG  . CYS D 2 474 ? 164.579 132.633 195.544 1.00 88.87  ? 490 CYS E SG  1 
ATOM   11766 N N   . ASN D 2 475 ? 163.924 136.208 196.429 1.00 69.78  ? 491 ASN E N   1 
ATOM   11767 C CA  . ASN D 2 475 ? 163.951 136.467 197.871 1.00 74.66  ? 491 ASN E CA  1 
ATOM   11768 C C   . ASN D 2 475 ? 165.277 137.075 198.330 1.00 69.54  ? 491 ASN E C   1 
ATOM   11769 O O   . ASN D 2 475 ? 166.023 136.493 199.119 1.00 71.20  ? 491 ASN E O   1 
ATOM   11770 C CB  . ASN D 2 475 ? 163.642 135.187 198.652 1.00 75.59  ? 491 ASN E CB  1 
ATOM   11771 C CG  . ASN D 2 475 ? 162.276 134.619 198.325 1.00 80.32  ? 491 ASN E CG  1 
ATOM   11772 O OD1 . ASN D 2 475 ? 162.151 133.457 197.938 1.00 89.22  ? 491 ASN E OD1 1 
ATOM   11773 N ND2 . ASN D 2 475 ? 161.242 135.437 198.481 1.00 76.36  ? 491 ASN E ND2 1 
ATOM   11774 N N   . GLY D 2 476 ? 165.563 138.270 197.822 1.00 61.97  ? 492 GLY E N   1 
ATOM   11775 C CA  . GLY D 2 476 ? 166.740 138.985 198.270 1.00 60.89  ? 492 GLY E CA  1 
ATOM   11776 C C   . GLY D 2 476 ? 168.052 138.473 197.729 1.00 64.64  ? 492 GLY E C   1 
ATOM   11777 O O   . GLY D 2 476 ? 169.110 138.927 198.175 1.00 62.62  ? 492 GLY E O   1 
ATOM   11778 N N   . SER D 2 477 ? 168.022 137.536 196.786 1.00 66.59  ? 493 SER E N   1 
ATOM   11779 C CA  . SER D 2 477 ? 169.226 137.035 196.144 1.00 61.19  ? 493 SER E CA  1 
ATOM   11780 C C   . SER D 2 477 ? 168.963 136.900 194.653 1.00 56.48  ? 493 SER E C   1 
ATOM   11781 O O   . SER D 2 477 ? 167.823 136.711 194.222 1.00 56.88  ? 493 SER E O   1 
ATOM   11782 C CB  . SER D 2 477 ? 169.669 135.688 196.730 1.00 65.95  ? 493 SER E CB  1 
ATOM   11783 O OG  . SER D 2 477 ? 168.660 134.705 196.578 1.00 65.12  ? 493 SER E OG  1 
ATOM   11784 N N   . ILE D 2 478 ? 170.030 137.000 193.870 1.00 54.92  ? 494 ILE E N   1 
ATOM   11785 C CA  . ILE D 2 478 ? 169.960 136.939 192.416 1.00 53.35  ? 494 ILE E CA  1 
ATOM   11786 C C   . ILE D 2 478 ? 170.737 135.717 191.955 1.00 55.80  ? 494 ILE E C   1 
ATOM   11787 O O   . ILE D 2 478 ? 171.892 135.522 192.353 1.00 61.40  ? 494 ILE E O   1 
ATOM   11788 C CB  . ILE D 2 478 ? 170.513 138.223 191.773 1.00 51.49  ? 494 ILE E CB  1 
ATOM   11789 C CG1 . ILE D 2 478 ? 169.499 139.364 191.900 1.00 46.29  ? 494 ILE E CG1 1 
ATOM   11790 C CG2 . ILE D 2 478 ? 170.891 137.977 190.324 1.00 49.42  ? 494 ILE E CG2 1 
ATOM   11791 C CD1 . ILE D 2 478 ? 168.530 139.460 190.744 1.00 44.58  ? 494 ILE E CD1 1 
ATOM   11792 N N   . TYR D 2 479 ? 170.105 134.894 191.125 1.00 54.85  ? 495 TYR E N   1 
ATOM   11793 C CA  . TYR D 2 479 ? 170.728 133.700 190.574 1.00 55.04  ? 495 TYR E CA  1 
ATOM   11794 C C   . TYR D 2 479 ? 171.093 133.946 189.118 1.00 55.26  ? 495 TYR E C   1 
ATOM   11795 O O   . TYR D 2 479 ? 170.255 134.400 188.332 1.00 59.86  ? 495 TYR E O   1 
ATOM   11796 C CB  . TYR D 2 479 ? 169.795 132.495 190.689 1.00 53.80  ? 495 TYR E CB  1 
ATOM   11797 C CG  . TYR D 2 479 ? 169.680 131.941 192.088 1.00 60.37  ? 495 TYR E CG  1 
ATOM   11798 C CD1 . TYR D 2 479 ? 170.799 131.484 192.766 1.00 65.54  ? 495 TYR E CD1 1 
ATOM   11799 C CD2 . TYR D 2 479 ? 168.454 131.880 192.732 1.00 69.47  ? 495 TYR E CD2 1 
ATOM   11800 C CE1 . TYR D 2 479 ? 170.700 130.977 194.045 1.00 70.04  ? 495 TYR E CE1 1 
ATOM   11801 C CE2 . TYR D 2 479 ? 168.346 131.375 194.012 1.00 77.12  ? 495 TYR E CE2 1 
ATOM   11802 C CZ  . TYR D 2 479 ? 169.473 130.925 194.663 1.00 76.66  ? 495 TYR E CZ  1 
ATOM   11803 O OH  . TYR D 2 479 ? 169.373 130.421 195.938 1.00 89.19  ? 495 TYR E OH  1 
ATOM   11804 N N   . VAL D 2 480 ? 172.339 133.650 188.762 1.00 54.26  ? 496 VAL E N   1 
ATOM   11805 C CA  . VAL D 2 480 ? 172.832 133.806 187.399 1.00 56.38  ? 496 VAL E CA  1 
ATOM   11806 C C   . VAL D 2 480 ? 173.066 132.420 186.819 1.00 59.11  ? 496 VAL E C   1 
ATOM   11807 O O   . VAL D 2 480 ? 173.806 131.614 187.396 1.00 66.27  ? 496 VAL E O   1 
ATOM   11808 C CB  . VAL D 2 480 ? 174.117 134.651 187.355 1.00 60.32  ? 496 VAL E CB  1 
ATOM   11809 C CG1 . VAL D 2 480 ? 174.000 135.734 186.295 1.00 58.48  ? 496 VAL E CG1 1 
ATOM   11810 C CG2 . VAL D 2 480 ? 174.399 135.265 188.715 1.00 59.11  ? 496 VAL E CG2 1 
ATOM   11811 N N   . PHE D 2 481 ? 172.438 132.143 185.680 1.00 58.22  ? 497 PHE E N   1 
ATOM   11812 C CA  . PHE D 2 481 ? 172.483 130.832 185.050 1.00 61.86  ? 497 PHE E CA  1 
ATOM   11813 C C   . PHE D 2 481 ? 173.343 130.883 183.796 1.00 67.70  ? 497 PHE E C   1 
ATOM   11814 O O   . PHE D 2 481 ? 173.260 131.832 183.011 1.00 67.33  ? 497 PHE E O   1 
ATOM   11815 C CB  . PHE D 2 481 ? 171.077 130.344 184.695 1.00 58.50  ? 497 PHE E CB  1 
ATOM   11816 C CG  . PHE D 2 481 ? 170.183 130.154 185.884 1.00 54.61  ? 497 PHE E CG  1 
ATOM   11817 C CD1 . PHE D 2 481 ? 169.429 131.204 186.375 1.00 53.35  ? 497 PHE E CD1 1 
ATOM   11818 C CD2 . PHE D 2 481 ? 170.096 128.925 186.509 1.00 54.33  ? 497 PHE E CD2 1 
ATOM   11819 C CE1 . PHE D 2 481 ? 168.607 131.032 187.466 1.00 54.08  ? 497 PHE E CE1 1 
ATOM   11820 C CE2 . PHE D 2 481 ? 169.276 128.747 187.602 1.00 55.34  ? 497 PHE E CE2 1 
ATOM   11821 C CZ  . PHE D 2 481 ? 168.530 129.802 188.081 1.00 57.99  ? 497 PHE E CZ  1 
ATOM   11822 N N   . ARG D 2 482 ? 174.162 129.853 183.610 1.00 75.75  ? 498 ARG E N   1 
ATOM   11823 C CA  . ARG D 2 482 ? 175.070 129.760 182.476 1.00 82.88  ? 498 ARG E CA  1 
ATOM   11824 C C   . ARG D 2 482 ? 174.419 128.946 181.367 1.00 89.50  ? 498 ARG E C   1 
ATOM   11825 O O   . ARG D 2 482 ? 173.987 127.811 181.595 1.00 89.76  ? 498 ARG E O   1 
ATOM   11826 C CB  . ARG D 2 482 ? 176.393 129.121 182.896 1.00 89.39  ? 498 ARG E CB  1 
ATOM   11827 C CG  . ARG D 2 482 ? 177.576 129.496 182.023 1.00 92.61  ? 498 ARG E CG  1 
ATOM   11828 C CD  . ARG D 2 482 ? 178.830 128.762 182.467 1.00 94.97  ? 498 ARG E CD  1 
ATOM   11829 N NE  . ARG D 2 482 ? 179.576 129.520 183.464 1.00 94.55  ? 498 ARG E NE  1 
ATOM   11830 C CZ  . ARG D 2 482 ? 180.689 130.194 183.212 1.00 99.05  ? 498 ARG E CZ  1 
ATOM   11831 N NH1 . ARG D 2 482 ? 181.220 130.223 182.001 1.00 106.16 ? 498 ARG E NH1 1 
ATOM   11832 N NH2 . ARG D 2 482 ? 181.283 130.857 184.200 1.00 99.88  ? 498 ARG E NH2 1 
ATOM   11833 N N   . ASP D 2 483 ? 174.345 129.532 180.170 1.00 90.63  ? 499 ASP E N   1 
ATOM   11834 C CA  . ASP D 2 483 ? 173.712 128.848 179.047 1.00 93.14  ? 499 ASP E CA  1 
ATOM   11835 C C   . ASP D 2 483 ? 174.505 127.617 178.623 1.00 99.62  ? 499 ASP E C   1 
ATOM   11836 O O   . ASP D 2 483 ? 173.922 126.561 178.348 1.00 99.95  ? 499 ASP E O   1 
ATOM   11837 C CB  . ASP D 2 483 ? 173.550 129.814 177.873 1.00 91.97  ? 499 ASP E CB  1 
ATOM   11838 C CG  . ASP D 2 483 ? 172.475 129.376 176.898 1.00 91.18  ? 499 ASP E CG  1 
ATOM   11839 O OD1 . ASP D 2 483 ? 172.447 128.184 176.531 1.00 92.26  ? 499 ASP E OD1 1 
ATOM   11840 O OD2 . ASP D 2 483 ? 171.654 130.229 176.499 1.00 90.38  ? 499 ASP E OD2 1 
ATOM   11841 N N   . ARG D 2 484 ? 175.830 127.729 178.565 1.00 101.63 ? 500 ARG E N   1 
ATOM   11842 C CA  . ARG D 2 484 ? 176.693 126.631 178.132 1.00 104.40 ? 500 ARG E CA  1 
ATOM   11843 C C   . ARG D 2 484 ? 177.252 125.949 179.377 1.00 105.09 ? 500 ARG E C   1 
ATOM   11844 O O   . ARG D 2 484 ? 178.308 126.317 179.892 1.00 104.78 ? 500 ARG E O   1 
ATOM   11845 C CB  . ARG D 2 484 ? 177.801 127.139 177.216 1.00 108.26 ? 500 ARG E CB  1 
ATOM   11846 C CG  . ARG D 2 484 ? 178.697 126.044 176.658 1.00 112.54 ? 500 ARG E CG  1 
ATOM   11847 C CD  . ARG D 2 484 ? 177.878 124.901 176.077 1.00 114.73 ? 500 ARG E CD  1 
ATOM   11848 N NE  . ARG D 2 484 ? 177.343 125.223 174.759 1.00 119.81 ? 500 ARG E NE  1 
ATOM   11849 C CZ  . ARG D 2 484 ? 176.647 124.381 174.009 1.00 120.26 ? 500 ARG E CZ  1 
ATOM   11850 N NH1 . ARG D 2 484 ? 176.378 123.151 174.416 1.00 121.51 ? 500 ARG E NH1 1 
ATOM   11851 N NH2 . ARG D 2 484 ? 176.207 124.783 172.819 1.00 116.83 ? 500 ARG E NH2 1 
ATOM   11852 N N   . TYR D 2 485 ? 176.528 124.945 179.861 1.00 105.58 ? 501 TYR E N   1 
ATOM   11853 C CA  . TYR D 2 485 ? 176.960 124.184 181.022 1.00 109.63 ? 501 TYR E CA  1 
ATOM   11854 C C   . TYR D 2 485 ? 178.091 123.237 180.643 1.00 114.58 ? 501 TYR E C   1 
ATOM   11855 O O   . TYR D 2 485 ? 178.121 122.693 179.535 1.00 115.18 ? 501 TYR E O   1 
ATOM   11856 C CB  . TYR D 2 485 ? 175.789 123.394 181.605 1.00 110.94 ? 501 TYR E CB  1 
ATOM   11857 C CG  . TYR D 2 485 ? 174.907 124.198 182.533 1.00 110.04 ? 501 TYR E CG  1 
ATOM   11858 C CD1 . TYR D 2 485 ? 175.450 125.127 183.411 1.00 106.32 ? 501 TYR E CD1 1 
ATOM   11859 C CD2 . TYR D 2 485 ? 173.528 124.035 182.523 1.00 109.99 ? 501 TYR E CD2 1 
ATOM   11860 C CE1 . TYR D 2 485 ? 174.643 125.866 184.258 1.00 104.73 ? 501 TYR E CE1 1 
ATOM   11861 C CE2 . TYR D 2 485 ? 172.714 124.769 183.364 1.00 106.48 ? 501 TYR E CE2 1 
ATOM   11862 C CZ  . TYR D 2 485 ? 173.276 125.682 184.230 1.00 103.33 ? 501 TYR E CZ  1 
ATOM   11863 O OH  . TYR D 2 485 ? 172.467 126.413 185.070 1.00 92.15  ? 501 TYR E OH  1 
ATOM   11864 N N   . LYS D 2 486 ? 179.026 123.043 181.569 1.00 117.87 ? 502 LYS E N   1 
ATOM   11865 C CA  . LYS D 2 486 ? 180.144 122.143 181.340 1.00 120.31 ? 502 LYS E CA  1 
ATOM   11866 C C   . LYS D 2 486 ? 179.737 120.702 181.645 1.00 121.05 ? 502 LYS E C   1 
ATOM   11867 O O   . LYS D 2 486 ? 178.591 120.408 181.996 1.00 119.16 ? 502 LYS E O   1 
ATOM   11868 C CB  . LYS D 2 486 ? 181.347 122.560 182.182 1.00 120.62 ? 502 LYS E CB  1 
ATOM   11869 C CG  . LYS D 2 486 ? 182.380 123.380 181.428 1.00 121.55 ? 502 LYS E CG  1 
ATOM   11870 C CD  . LYS D 2 486 ? 183.712 123.385 182.159 1.00 122.35 ? 502 LYS E CD  1 
ATOM   11871 C CE  . LYS D 2 486 ? 184.792 124.063 181.335 1.00 122.34 ? 502 LYS E CE  1 
ATOM   11872 N NZ  . LYS D 2 486 ? 186.129 123.963 181.983 1.00 120.11 ? 502 LYS E NZ  1 
ATOM   11873 N N   . LYS D 2 487 ? 180.695 119.789 181.506 1.00 123.93 ? 503 LYS E N   1 
ATOM   11874 C CA  . LYS D 2 487 ? 180.462 118.376 181.783 1.00 125.83 ? 503 LYS E CA  1 
ATOM   11875 C C   . LYS D 2 487 ? 180.555 118.147 183.287 1.00 124.40 ? 503 LYS E C   1 
ATOM   11876 O O   . LYS D 2 487 ? 181.633 118.269 183.877 1.00 122.85 ? 503 LYS E O   1 
ATOM   11877 C CB  . LYS D 2 487 ? 181.471 117.512 181.031 1.00 125.50 ? 503 LYS E CB  1 
ATOM   11878 C CG  . LYS D 2 487 ? 181.116 116.032 180.963 1.00 124.43 ? 503 LYS E CG  1 
ATOM   11879 C CD  . LYS D 2 487 ? 179.611 115.808 180.930 1.00 124.71 ? 503 LYS E CD  1 
ATOM   11880 C CE  . LYS D 2 487 ? 179.276 114.326 180.926 1.00 125.47 ? 503 LYS E CE  1 
ATOM   11881 N NZ  . LYS D 2 487 ? 177.950 114.055 181.548 1.00 123.71 ? 503 LYS E NZ  1 
ATOM   11882 N N   . GLY D 2 488 ? 179.425 117.816 183.908 1.00 122.61 ? 504 GLY E N   1 
ATOM   11883 C CA  . GLY D 2 488 ? 179.384 117.563 185.331 1.00 121.30 ? 504 GLY E CA  1 
ATOM   11884 C C   . GLY D 2 488 ? 179.377 118.796 186.206 1.00 121.92 ? 504 GLY E C   1 
ATOM   11885 O O   . GLY D 2 488 ? 179.448 118.662 187.434 1.00 120.31 ? 504 GLY E O   1 
ATOM   11886 N N   . ASP D 2 489 ? 179.297 119.990 185.622 1.00 123.43 ? 505 ASP E N   1 
ATOM   11887 C CA  . ASP D 2 489 ? 179.311 121.243 186.371 1.00 119.59 ? 505 ASP E CA  1 
ATOM   11888 C C   . ASP D 2 489 ? 178.031 122.009 186.068 1.00 116.40 ? 505 ASP E C   1 
ATOM   11889 O O   . ASP D 2 489 ? 177.874 122.555 184.970 1.00 114.51 ? 505 ASP E O   1 
ATOM   11890 C CB  . ASP D 2 489 ? 180.542 122.078 186.021 1.00 119.41 ? 505 ASP E CB  1 
ATOM   11891 C CG  . ASP D 2 489 ? 181.814 121.526 186.630 1.00 121.78 ? 505 ASP E CG  1 
ATOM   11892 O OD1 . ASP D 2 489 ? 181.735 120.888 187.700 1.00 121.66 ? 505 ASP E OD1 1 
ATOM   11893 O OD2 . ASP D 2 489 ? 182.895 121.732 186.038 1.00 120.74 ? 505 ASP E OD2 1 
ATOM   11894 N N   . ALA D 2 490 ? 177.117 122.048 187.038 1.00 116.97 ? 506 ALA E N   1 
ATOM   11895 C CA  . ALA D 2 490 ? 175.918 122.880 186.947 1.00 114.91 ? 506 ALA E CA  1 
ATOM   11896 C C   . ALA D 2 490 ? 176.287 124.276 187.438 1.00 107.82 ? 506 ALA E C   1 
ATOM   11897 O O   . ALA D 2 490 ? 176.092 124.642 188.600 1.00 105.25 ? 506 ALA E O   1 
ATOM   11898 C CB  . ALA D 2 490 ? 174.773 122.277 187.751 1.00 112.89 ? 506 ALA E CB  1 
ATOM   11899 N N   . ASN D 2 491 ? 176.839 125.071 186.523 1.00 105.46 ? 507 ASN E N   1 
ATOM   11900 C CA  . ASN D 2 491 ? 177.421 126.366 186.869 1.00 101.88 ? 507 ASN E CA  1 
ATOM   11901 C C   . ASN D 2 491 ? 176.302 127.367 187.126 1.00 97.01  ? 507 ASN E C   1 
ATOM   11902 O O   . ASN D 2 491 ? 175.805 128.034 186.218 1.00 92.71  ? 507 ASN E O   1 
ATOM   11903 C CB  . ASN D 2 491 ? 178.359 126.845 185.768 1.00 100.63 ? 507 ASN E CB  1 
ATOM   11904 C CG  . ASN D 2 491 ? 179.807 126.886 186.217 1.00 101.53 ? 507 ASN E CG  1 
ATOM   11905 O OD1 . ASN D 2 491 ? 180.133 126.484 187.334 1.00 99.52  ? 507 ASN E OD1 1 
ATOM   11906 N ND2 . ASN D 2 491 ? 180.684 127.374 185.347 1.00 100.35 ? 507 ASN E ND2 1 
ATOM   11907 N N   . THR D 2 492 ? 175.905 127.469 188.390 1.00 96.72  ? 508 THR E N   1 
ATOM   11908 C CA  . THR D 2 492 ? 174.953 128.466 188.851 1.00 88.18  ? 508 THR E CA  1 
ATOM   11909 C C   . THR D 2 492 ? 175.617 129.317 189.923 1.00 87.80  ? 508 THR E C   1 
ATOM   11910 O O   . THR D 2 492 ? 176.327 128.797 190.789 1.00 91.63  ? 508 THR E O   1 
ATOM   11911 C CB  . THR D 2 492 ? 173.686 127.820 189.416 1.00 87.39  ? 508 THR E CB  1 
ATOM   11912 O OG1 . THR D 2 492 ? 174.042 126.682 190.209 1.00 94.24  ? 508 THR E OG1 1 
ATOM   11913 C CG2 . THR D 2 492 ? 172.771 127.375 188.291 1.00 85.69  ? 508 THR E CG2 1 
ATOM   11914 N N   . TYR D 2 493 ? 175.387 130.623 189.859 1.00 80.06  ? 509 TYR E N   1 
ATOM   11915 C CA  . TYR D 2 493 ? 175.973 131.570 190.793 1.00 75.14  ? 509 TYR E CA  1 
ATOM   11916 C C   . TYR D 2 493 ? 174.868 132.316 191.522 1.00 69.04  ? 509 TYR E C   1 
ATOM   11917 O O   . TYR D 2 493 ? 173.880 132.732 190.910 1.00 69.38  ? 509 TYR E O   1 
ATOM   11918 C CB  . TYR D 2 493 ? 176.883 132.566 190.069 1.00 77.46  ? 509 TYR E CB  1 
ATOM   11919 C CG  . TYR D 2 493 ? 178.167 131.965 189.546 1.00 83.43  ? 509 TYR E CG  1 
ATOM   11920 C CD1 . TYR D 2 493 ? 179.268 131.801 190.374 1.00 87.54  ? 509 TYR E CD1 1 
ATOM   11921 C CD2 . TYR D 2 493 ? 178.280 131.569 188.220 1.00 84.62  ? 509 TYR E CD2 1 
ATOM   11922 C CE1 . TYR D 2 493 ? 180.444 131.255 189.899 1.00 88.67  ? 509 TYR E CE1 1 
ATOM   11923 C CE2 . TYR D 2 493 ? 179.452 131.022 187.737 1.00 87.60  ? 509 TYR E CE2 1 
ATOM   11924 C CZ  . TYR D 2 493 ? 180.530 130.868 188.580 1.00 89.03  ? 509 TYR E CZ  1 
ATOM   11925 O OH  . TYR D 2 493 ? 181.699 130.323 188.104 1.00 87.48  ? 509 TYR E OH  1 
ATOM   11926 N N   . LYS D 2 494 ? 175.033 132.478 192.830 1.00 69.80  ? 510 LYS E N   1 
ATOM   11927 C CA  . LYS D 2 494 ? 174.125 133.277 193.640 1.00 69.81  ? 510 LYS E CA  1 
ATOM   11928 C C   . LYS D 2 494 ? 174.803 134.592 193.992 1.00 69.94  ? 510 LYS E C   1 
ATOM   11929 O O   . LYS D 2 494 ? 175.921 134.599 194.516 1.00 75.31  ? 510 LYS E O   1 
ATOM   11930 C CB  . LYS D 2 494 ? 173.718 132.535 194.913 1.00 74.65  ? 510 LYS E CB  1 
ATOM   11931 C CG  . LYS D 2 494 ? 173.180 133.441 196.010 1.00 73.55  ? 510 LYS E CG  1 
ATOM   11932 C CD  . LYS D 2 494 ? 172.248 132.690 196.943 1.00 79.79  ? 510 LYS E CD  1 
ATOM   11933 C CE  . LYS D 2 494 ? 173.015 131.712 197.816 1.00 89.40  ? 510 LYS E CE  1 
ATOM   11934 N NZ  . LYS D 2 494 ? 173.246 132.250 199.185 1.00 92.68  ? 510 LYS E NZ  1 
ATOM   11935 N N   . LEU D 2 495 ? 174.129 135.699 193.703 1.00 64.81  ? 511 LEU E N   1 
ATOM   11936 C CA  . LEU D 2 495 ? 174.670 137.029 193.938 1.00 62.04  ? 511 LEU E CA  1 
ATOM   11937 C C   . LEU D 2 495 ? 173.832 137.749 194.982 1.00 62.35  ? 511 LEU E C   1 
ATOM   11938 O O   . LEU D 2 495 ? 172.600 137.752 194.902 1.00 63.56  ? 511 LEU E O   1 
ATOM   11939 C CB  . LEU D 2 495 ? 174.707 137.840 192.642 1.00 57.84  ? 511 LEU E CB  1 
ATOM   11940 C CG  . LEU D 2 495 ? 174.705 139.355 192.830 1.00 60.32  ? 511 LEU E CG  1 
ATOM   11941 C CD1 . LEU D 2 495 ? 176.104 139.844 193.143 1.00 64.02  ? 511 LEU E CD1 1 
ATOM   11942 C CD2 . LEU D 2 495 ? 174.154 140.047 191.600 1.00 58.18  ? 511 LEU E CD2 1 
ATOM   11943 N N   . ASP D 2 496 ? 174.501 138.351 195.960 1.00 61.48  ? 512 ASP E N   1 
ATOM   11944 C CA  . ASP D 2 496 ? 173.831 139.199 196.936 1.00 59.42  ? 512 ASP E CA  1 
ATOM   11945 C C   . ASP D 2 496 ? 174.124 140.650 196.588 1.00 58.46  ? 512 ASP E C   1 
ATOM   11946 O O   . ASP D 2 496 ? 175.271 141.099 196.748 1.00 59.85  ? 512 ASP E O   1 
ATOM   11947 C CB  . ASP D 2 496 ? 174.299 138.878 198.355 1.00 58.18  ? 512 ASP E CB  1 
ATOM   11948 C CG  . ASP D 2 496 ? 173.926 139.956 199.348 1.00 58.01  ? 512 ASP E CG  1 
ATOM   11949 O OD1 . ASP D 2 496 ? 172.733 140.056 199.702 1.00 54.75  ? 512 ASP E OD1 1 
ATOM   11950 O OD2 . ASP D 2 496 ? 174.826 140.705 199.776 1.00 60.89  ? 512 ASP E OD2 1 
ATOM   11951 N N   . PRO D 2 497 ? 173.141 141.415 196.105 1.00 54.77  ? 513 PRO E N   1 
ATOM   11952 C CA  . PRO D 2 497 ? 173.440 142.761 195.590 1.00 51.78  ? 513 PRO E CA  1 
ATOM   11953 C C   . PRO D 2 497 ? 173.949 143.733 196.639 1.00 52.23  ? 513 PRO E C   1 
ATOM   11954 O O   . PRO D 2 497 ? 174.575 144.734 196.270 1.00 50.47  ? 513 PRO E O   1 
ATOM   11955 C CB  . PRO D 2 497 ? 172.097 143.221 195.008 1.00 43.65  ? 513 PRO E CB  1 
ATOM   11956 C CG  . PRO D 2 497 ? 171.075 142.408 195.719 1.00 42.01  ? 513 PRO E CG  1 
ATOM   11957 C CD  . PRO D 2 497 ? 171.709 141.087 196.010 1.00 51.45  ? 513 PRO E CD  1 
ATOM   11958 N N   . ALA D 2 498 ? 173.703 143.482 197.926 1.00 53.51  ? 514 ALA E N   1 
ATOM   11959 C CA  . ALA D 2 498 ? 174.133 144.422 198.955 1.00 47.41  ? 514 ALA E CA  1 
ATOM   11960 C C   . ALA D 2 498 ? 175.653 144.492 199.045 1.00 53.19  ? 514 ALA E C   1 
ATOM   11961 O O   . ALA D 2 498 ? 176.236 145.581 199.007 1.00 56.25  ? 514 ALA E O   1 
ATOM   11962 C CB  . ALA D 2 498 ? 173.529 144.034 200.304 1.00 43.21  ? 514 ALA E CB  1 
ATOM   11963 N N   . THR D 2 499 ? 176.317 143.342 199.150 1.00 57.50  ? 515 THR E N   1 
ATOM   11964 C CA  . THR D 2 499 ? 177.769 143.299 199.278 1.00 62.00  ? 515 THR E CA  1 
ATOM   11965 C C   . THR D 2 499 ? 178.460 142.824 198.005 1.00 64.70  ? 515 THR E C   1 
ATOM   11966 O O   . THR D 2 499 ? 179.690 142.711 197.988 1.00 65.99  ? 515 THR E O   1 
ATOM   11967 C CB  . THR D 2 499 ? 178.173 142.414 200.459 1.00 63.70  ? 515 THR E CB  1 
ATOM   11968 O OG1 . THR D 2 499 ? 179.554 142.635 200.772 1.00 66.06  ? 515 THR E OG1 1 
ATOM   11969 C CG2 . THR D 2 499 ? 177.968 140.950 200.126 1.00 65.14  ? 515 THR E CG2 1 
ATOM   11970 N N   . SER D 2 500 ? 177.699 142.552 196.943 1.00 64.94  ? 516 SER E N   1 
ATOM   11971 C CA  . SER D 2 500 ? 178.250 142.178 195.637 1.00 68.03  ? 516 SER E CA  1 
ATOM   11972 C C   . SER D 2 500 ? 179.123 140.927 195.727 1.00 69.98  ? 516 SER E C   1 
ATOM   11973 O O   . SER D 2 500 ? 180.143 140.810 195.046 1.00 69.87  ? 516 SER E O   1 
ATOM   11974 C CB  . SER D 2 500 ? 179.030 143.339 195.016 1.00 67.35  ? 516 SER E CB  1 
ATOM   11975 O OG  . SER D 2 500 ? 178.178 144.178 194.257 1.00 67.51  ? 516 SER E OG  1 
ATOM   11976 N N   . ALA D 2 501 ? 178.718 139.982 196.569 1.00 67.99  ? 517 ALA E N   1 
ATOM   11977 C CA  . ALA D 2 501 ? 179.433 138.725 196.739 1.00 68.82  ? 517 ALA E CA  1 
ATOM   11978 C C   . ALA D 2 501 ? 178.757 137.651 195.898 1.00 72.69  ? 517 ALA E C   1 
ATOM   11979 O O   . ALA D 2 501 ? 177.569 137.367 196.083 1.00 70.48  ? 517 ALA E O   1 
ATOM   11980 C CB  . ALA D 2 501 ? 179.473 138.308 198.208 1.00 71.10  ? 517 ALA E CB  1 
ATOM   11981 N N   . VAL D 2 502 ? 179.515 137.053 194.984 1.00 75.46  ? 518 VAL E N   1 
ATOM   11982 C CA  . VAL D 2 502 ? 179.022 136.003 194.102 1.00 73.21  ? 518 VAL E CA  1 
ATOM   11983 C C   . VAL D 2 502 ? 179.561 134.676 194.616 1.00 73.84  ? 518 VAL E C   1 
ATOM   11984 O O   . VAL D 2 502 ? 180.778 134.505 194.758 1.00 76.92  ? 518 VAL E O   1 
ATOM   11985 C CB  . VAL D 2 502 ? 179.443 136.242 192.644 1.00 73.60  ? 518 VAL E CB  1 
ATOM   11986 C CG1 . VAL D 2 502 ? 178.982 135.094 191.767 1.00 75.05  ? 518 VAL E CG1 1 
ATOM   11987 C CG2 . VAL D 2 502 ? 178.888 137.564 192.140 1.00 73.01  ? 518 VAL E CG2 1 
ATOM   11988 N N   . THR D 2 503 ? 178.661 133.743 194.895 1.00 76.55  ? 519 THR E N   1 
ATOM   11989 C CA  . THR D 2 503 ? 179.020 132.434 195.421 1.00 79.85  ? 519 THR E CA  1 
ATOM   11990 C C   . THR D 2 503 ? 178.605 131.355 194.422 1.00 85.45  ? 519 THR E C   1 
ATOM   11991 O O   . THR D 2 503 ? 178.162 131.644 193.308 1.00 85.47  ? 519 THR E O   1 
ATOM   11992 C CB  . THR D 2 503 ? 178.383 132.208 196.794 1.00 79.05  ? 519 THR E CB  1 
ATOM   11993 O OG1 . THR D 2 503 ? 178.726 130.901 197.271 1.00 80.44  ? 519 THR E OG1 1 
ATOM   11994 C CG2 . THR D 2 503 ? 176.875 132.324 196.706 1.00 77.87  ? 519 THR E CG2 1 
ATOM   11995 N N   . VAL D 2 504 ? 178.756 130.100 194.832 1.00 89.50  ? 520 VAL E N   1 
ATOM   11996 C CA  . VAL D 2 504 ? 178.467 128.947 193.991 1.00 90.39  ? 520 VAL E CA  1 
ATOM   11997 C C   . VAL D 2 504 ? 177.428 128.090 194.700 1.00 92.97  ? 520 VAL E C   1 
ATOM   11998 O O   . VAL D 2 504 ? 177.502 127.889 195.917 1.00 94.44  ? 520 VAL E O   1 
ATOM   11999 C CB  . VAL D 2 504 ? 179.750 128.146 193.685 1.00 91.10  ? 520 VAL E CB  1 
ATOM   12000 C CG1 . VAL D 2 504 ? 179.425 126.718 193.318 1.00 95.62  ? 520 VAL E CG1 1 
ATOM   12001 C CG2 . VAL D 2 504 ? 180.537 128.817 192.571 1.00 88.16  ? 520 VAL E CG2 1 
ATOM   12002 N N   . THR D 2 505 ? 176.460 127.584 193.936 1.00 93.94  ? 521 THR E N   1 
ATOM   12003 C CA  . THR D 2 505 ? 175.288 126.939 194.515 1.00 97.28  ? 521 THR E CA  1 
ATOM   12004 C C   . THR D 2 505 ? 175.183 125.471 194.121 1.00 102.61 ? 521 THR E C   1 
ATOM   12005 O O   . THR D 2 505 ? 174.123 125.023 193.672 1.00 105.81 ? 521 THR E O   1 
ATOM   12006 C CB  . THR D 2 505 ? 174.013 127.677 194.100 1.00 96.16  ? 521 THR E CB  1 
ATOM   12007 O OG1 . THR D 2 505 ? 174.157 128.169 192.763 1.00 92.24  ? 521 THR E OG1 1 
ATOM   12008 C CG2 . THR D 2 505 ? 173.745 128.840 195.039 1.00 88.68  ? 521 THR E CG2 1 
ATOM   12009 N N   . ARG D 2 506 ? 176.278 124.723 194.261 1.00 104.49 ? 522 ARG E N   1 
ATOM   12010 C CA  . ARG D 2 506 ? 176.240 123.288 194.006 1.00 109.52 ? 522 ARG E CA  1 
ATOM   12011 C C   . ARG D 2 506 ? 175.174 122.627 194.869 1.00 110.87 ? 522 ARG E C   1 
ATOM   12012 O O   . ARG D 2 506 ? 175.062 122.906 196.066 1.00 109.76 ? 522 ARG E O   1 
ATOM   12013 C CB  . ARG D 2 506 ? 177.604 122.657 194.284 1.00 109.83 ? 522 ARG E CB  1 
ATOM   12014 C CG  . ARG D 2 506 ? 178.757 123.303 193.543 1.00 107.28 ? 522 ARG E CG  1 
ATOM   12015 C CD  . ARG D 2 506 ? 179.045 122.603 192.227 1.00 107.53 ? 522 ARG E CD  1 
ATOM   12016 N NE  . ARG D 2 506 ? 179.838 123.442 191.336 1.00 110.56 ? 522 ARG E NE  1 
ATOM   12017 C CZ  . ARG D 2 506 ? 179.550 123.658 190.059 1.00 112.03 ? 522 ARG E CZ  1 
ATOM   12018 N NH1 . ARG D 2 506 ? 178.495 123.104 189.485 1.00 110.73 ? 522 ARG E NH1 1 
ATOM   12019 N NH2 . ARG D 2 506 ? 180.341 124.450 189.341 1.00 112.99 ? 522 ARG E NH2 1 
ATOM   12020 N N   . GLY D 2 507 ? 174.390 121.747 194.254 1.00 113.61 ? 523 GLY E N   1 
ATOM   12021 C CA  . GLY D 2 507 ? 173.273 121.120 194.929 1.00 116.73 ? 523 GLY E CA  1 
ATOM   12022 C C   . GLY D 2 507 ? 172.051 121.067 194.039 1.00 119.19 ? 523 GLY E C   1 
ATOM   12023 O O   . GLY D 2 507 ? 171.205 120.178 194.175 1.00 121.20 ? 523 GLY E O   1 
ATOM   12024 N N   . ILE D 2 508 ? 171.951 122.024 193.122 1.00 118.74 ? 524 ILE E N   1 
ATOM   12025 C CA  . ILE D 2 508 ? 170.881 122.032 192.131 1.00 120.73 ? 524 ILE E CA  1 
ATOM   12026 C C   . ILE D 2 508 ? 171.314 121.156 190.960 1.00 121.53 ? 524 ILE E C   1 
ATOM   12027 O O   . ILE D 2 508 ? 172.313 121.438 190.290 1.00 123.16 ? 524 ILE E O   1 
ATOM   12028 C CB  . ILE D 2 508 ? 170.553 123.467 191.684 1.00 118.96 ? 524 ILE E CB  1 
ATOM   12029 C CG1 . ILE D 2 508 ? 169.550 123.472 190.529 1.00 115.61 ? 524 ILE E CG1 1 
ATOM   12030 C CG2 . ILE D 2 508 ? 171.822 124.250 191.343 1.00 114.56 ? 524 ILE E CG2 1 
ATOM   12031 C CD1 . ILE D 2 508 ? 168.321 122.628 190.772 1.00 111.63 ? 524 ILE E CD1 1 
ATOM   12032 N N   . LYS D 2 509 ? 170.574 120.076 190.726 1.00 121.50 ? 525 LYS E N   1 
ATOM   12033 C CA  . LYS D 2 509 ? 170.979 119.049 189.766 1.00 122.58 ? 525 LYS E CA  1 
ATOM   12034 C C   . LYS D 2 509 ? 170.325 119.233 188.398 1.00 121.38 ? 525 LYS E C   1 
ATOM   12035 O O   . LYS D 2 509 ? 169.642 118.347 187.890 1.00 117.85 ? 525 LYS E O   1 
ATOM   12036 C CB  . LYS D 2 509 ? 170.685 117.667 190.343 1.00 123.53 ? 525 LYS E CB  1 
ATOM   12037 C CG  . LYS D 2 509 ? 169.351 117.541 191.079 1.00 120.87 ? 525 LYS E CG  1 
ATOM   12038 C CD  . LYS D 2 509 ? 168.256 116.965 190.193 1.00 118.32 ? 525 LYS E CD  1 
ATOM   12039 C CE  . LYS D 2 509 ? 166.918 116.927 190.909 1.00 114.35 ? 525 LYS E CE  1 
ATOM   12040 N NZ  . LYS D 2 509 ? 165.818 116.508 189.996 1.00 109.98 ? 525 LYS E NZ  1 
ATOM   12041 N N   . VAL D 2 510 ? 170.549 120.386 187.770 1.00 123.99 ? 526 VAL E N   1 
ATOM   12042 C CA  . VAL D 2 510 ? 170.034 120.607 186.423 1.00 122.38 ? 526 VAL E CA  1 
ATOM   12043 C C   . VAL D 2 510 ? 170.787 119.716 185.440 1.00 120.92 ? 526 VAL E C   1 
ATOM   12044 O O   . VAL D 2 510 ? 172.023 119.697 185.406 1.00 121.68 ? 526 VAL E O   1 
ATOM   12045 C CB  . VAL D 2 510 ? 170.095 122.097 186.023 1.00 118.18 ? 526 VAL E CB  1 
ATOM   12046 C CG1 . VAL D 2 510 ? 169.391 122.945 187.059 1.00 111.59 ? 526 VAL E CG1 1 
ATOM   12047 C CG2 . VAL D 2 510 ? 171.531 122.578 185.876 1.00 116.38 ? 526 VAL E CG2 1 
ATOM   12048 N N   . LEU D 2 511 ? 170.040 118.924 184.674 1.00 118.05 ? 527 LEU E N   1 
ATOM   12049 C CA  . LEU D 2 511 ? 170.613 118.088 183.630 1.00 118.83 ? 527 LEU E CA  1 
ATOM   12050 C C   . LEU D 2 511 ? 170.534 118.731 182.253 1.00 116.99 ? 527 LEU E C   1 
ATOM   12051 O O   . LEU D 2 511 ? 170.957 118.111 181.272 1.00 117.60 ? 527 LEU E O   1 
ATOM   12052 C CB  . LEU D 2 511 ? 169.919 116.720 183.597 1.00 119.68 ? 527 LEU E CB  1 
ATOM   12053 C CG  . LEU D 2 511 ? 168.411 116.670 183.335 1.00 119.33 ? 527 LEU E CG  1 
ATOM   12054 C CD1 . LEU D 2 511 ? 168.042 115.370 182.639 1.00 117.59 ? 527 LEU E CD1 1 
ATOM   12055 C CD2 . LEU D 2 511 ? 167.621 116.820 184.628 1.00 118.08 ? 527 LEU E CD2 1 
ATOM   12056 N N   . LEU D 2 512 ? 170.001 119.947 182.158 1.00 113.86 ? 528 LEU E N   1 
ATOM   12057 C CA  . LEU D 2 512 ? 169.850 120.625 180.878 1.00 111.87 ? 528 LEU E CA  1 
ATOM   12058 C C   . LEU D 2 512 ? 171.190 121.150 180.380 1.00 114.03 ? 528 LEU E C   1 
ATOM   12059 O O   . LEU D 2 512 ? 171.755 122.079 180.966 1.00 113.24 ? 528 LEU E O   1 
ATOM   12060 C CB  . LEU D 2 512 ? 168.841 121.768 180.999 1.00 105.65 ? 528 LEU E CB  1 
ATOM   12061 C CG  . LEU D 2 512 ? 167.496 121.409 181.635 1.00 101.13 ? 528 LEU E CG  1 
ATOM   12062 C CD1 . LEU D 2 512 ? 166.549 122.593 181.594 1.00 87.57  ? 528 LEU E CD1 1 
ATOM   12063 C CD2 . LEU D 2 512 ? 166.880 120.206 180.941 1.00 107.35 ? 528 LEU E CD2 1 
ATOM   12064 N N   . THR D 2 513 ? 171.710 120.555 179.304 1.00 114.51 ? 529 THR E N   1 
ATOM   12065 C CA  . THR D 2 513 ? 172.957 121.041 178.722 1.00 111.03 ? 529 THR E CA  1 
ATOM   12066 C C   . THR D 2 513 ? 172.794 122.453 178.173 1.00 108.67 ? 529 THR E C   1 
ATOM   12067 O O   . THR D 2 513 ? 173.662 123.311 178.378 1.00 109.03 ? 529 THR E O   1 
ATOM   12068 C CB  . THR D 2 513 ? 173.427 120.083 177.626 1.00 115.07 ? 529 THR E CB  1 
ATOM   12069 O OG1 . THR D 2 513 ? 173.958 118.895 178.225 1.00 115.96 ? 529 THR E OG1 1 
ATOM   12070 C CG2 . THR D 2 513 ? 174.500 120.730 176.763 1.00 115.72 ? 529 THR E CG2 1 
ATOM   12071 N N   . ASN D 2 514 ? 171.686 122.718 177.489 1.00 104.51 ? 530 ASN E N   1 
ATOM   12072 C CA  . ASN D 2 514 ? 171.395 124.025 176.920 1.00 99.39  ? 530 ASN E CA  1 
ATOM   12073 C C   . ASN D 2 514 ? 170.169 124.620 177.601 1.00 97.54  ? 530 ASN E C   1 
ATOM   12074 O O   . ASN D 2 514 ? 169.144 123.949 177.751 1.00 98.98  ? 530 ASN E O   1 
ATOM   12075 C CB  . ASN D 2 514 ? 171.164 123.922 175.409 1.00 98.94  ? 530 ASN E CB  1 
ATOM   12076 C CG  . ASN D 2 514 ? 170.253 125.014 174.878 1.00 96.32  ? 530 ASN E CG  1 
ATOM   12077 O OD1 . ASN D 2 514 ? 170.689 126.137 174.631 1.00 94.13  ? 530 ASN E OD1 1 
ATOM   12078 N ND2 . ASN D 2 514 ? 168.980 124.683 174.692 1.00 93.57  ? 530 ASN E ND2 1 
ATOM   12079 N N   . LEU D 2 515 ? 170.282 125.880 178.015 1.00 91.90  ? 531 LEU E N   1 
ATOM   12080 C CA  . LEU D 2 515 ? 169.193 126.606 178.661 1.00 84.55  ? 531 LEU E CA  1 
ATOM   12081 C C   . LEU D 2 515 ? 168.557 127.530 177.630 1.00 81.47  ? 531 LEU E C   1 
ATOM   12082 O O   . LEU D 2 515 ? 169.217 128.433 177.107 1.00 81.60  ? 531 LEU E O   1 
ATOM   12083 C CB  . LEU D 2 515 ? 169.697 127.395 179.867 1.00 82.38  ? 531 LEU E CB  1 
ATOM   12084 C CG  . LEU D 2 515 ? 169.400 126.803 181.246 1.00 77.52  ? 531 LEU E CG  1 
ATOM   12085 C CD1 . LEU D 2 515 ? 170.276 127.450 182.304 1.00 76.36  ? 531 LEU E CD1 1 
ATOM   12086 C CD2 . LEU D 2 515 ? 167.931 126.963 181.593 1.00 70.76  ? 531 LEU E CD2 1 
ATOM   12087 N N   . GLN D 2 516 ? 167.277 127.303 177.341 1.00 77.26  ? 532 GLN E N   1 
ATOM   12088 C CA  . GLN D 2 516 ? 166.555 128.119 176.370 1.00 71.77  ? 532 GLN E CA  1 
ATOM   12089 C C   . GLN D 2 516 ? 165.932 129.346 177.028 1.00 67.18  ? 532 GLN E C   1 
ATOM   12090 O O   . GLN D 2 516 ? 166.215 130.482 176.635 1.00 68.14  ? 532 GLN E O   1 
ATOM   12091 C CB  . GLN D 2 516 ? 165.481 127.278 175.673 1.00 74.81  ? 532 GLN E CB  1 
ATOM   12092 C CG  . GLN D 2 516 ? 165.537 127.333 174.157 1.00 81.33  ? 532 GLN E CG  1 
ATOM   12093 C CD  . GLN D 2 516 ? 164.396 126.579 173.503 1.00 88.32  ? 532 GLN E CD  1 
ATOM   12094 O OE1 . GLN D 2 516 ? 163.880 125.608 174.056 1.00 90.13  ? 532 GLN E OE1 1 
ATOM   12095 N NE2 . GLN D 2 516 ? 163.993 127.026 172.319 1.00 84.18  ? 532 GLN E NE2 1 
ATOM   12096 N N   . PHE D 2 517 ? 165.085 129.130 178.032 1.00 63.88  ? 533 PHE E N   1 
ATOM   12097 C CA  . PHE D 2 517 ? 164.391 130.204 178.723 1.00 56.84  ? 533 PHE E CA  1 
ATOM   12098 C C   . PHE D 2 517 ? 164.546 130.036 180.226 1.00 56.17  ? 533 PHE E C   1 
ATOM   12099 O O   . PHE D 2 517 ? 164.478 128.919 180.744 1.00 58.47  ? 533 PHE E O   1 
ATOM   12100 C CB  . PHE D 2 517 ? 162.899 130.231 178.364 1.00 58.55  ? 533 PHE E CB  1 
ATOM   12101 C CG  . PHE D 2 517 ? 162.627 130.468 176.907 1.00 62.09  ? 533 PHE E CG  1 
ATOM   12102 C CD1 . PHE D 2 517 ? 162.577 131.754 176.399 1.00 62.07  ? 533 PHE E CD1 1 
ATOM   12103 C CD2 . PHE D 2 517 ? 162.414 129.407 176.047 1.00 64.53  ? 533 PHE E CD2 1 
ATOM   12104 C CE1 . PHE D 2 517 ? 162.326 131.975 175.063 1.00 59.61  ? 533 PHE E CE1 1 
ATOM   12105 C CE2 . PHE D 2 517 ? 162.163 129.622 174.709 1.00 65.90  ? 533 PHE E CE2 1 
ATOM   12106 C CZ  . PHE D 2 517 ? 162.119 130.908 174.217 1.00 65.61  ? 533 PHE E CZ  1 
ATOM   12107 N N   . VAL D 2 518 ? 164.760 131.151 180.919 1.00 55.45  ? 534 VAL E N   1 
ATOM   12108 C CA  . VAL D 2 518 ? 164.701 131.214 182.375 1.00 51.93  ? 534 VAL E CA  1 
ATOM   12109 C C   . VAL D 2 518 ? 163.641 132.244 182.731 1.00 49.26  ? 534 VAL E C   1 
ATOM   12110 O O   . VAL D 2 518 ? 163.767 133.420 182.372 1.00 50.62  ? 534 VAL E O   1 
ATOM   12111 C CB  . VAL D 2 518 ? 166.058 131.582 182.995 1.00 49.72  ? 534 VAL E CB  1 
ATOM   12112 C CG1 . VAL D 2 518 ? 165.898 131.880 184.474 1.00 50.42  ? 534 VAL E CG1 1 
ATOM   12113 C CG2 . VAL D 2 518 ? 167.060 130.462 182.782 1.00 51.98  ? 534 VAL E CG2 1 
ATOM   12114 N N   . LEU D 2 519 ? 162.597 131.806 183.429 1.00 51.68  ? 535 LEU E N   1 
ATOM   12115 C CA  . LEU D 2 519 ? 161.420 132.625 183.676 1.00 50.89  ? 535 LEU E CA  1 
ATOM   12116 C C   . LEU D 2 519 ? 161.168 132.757 185.170 1.00 51.39  ? 535 LEU E C   1 
ATOM   12117 O O   . LEU D 2 519 ? 161.280 131.783 185.919 1.00 59.17  ? 535 LEU E O   1 
ATOM   12118 C CB  . LEU D 2 519 ? 160.187 132.030 182.989 1.00 53.56  ? 535 LEU E CB  1 
ATOM   12119 C CG  . LEU D 2 519 ? 160.417 131.481 181.581 1.00 51.94  ? 535 LEU E CG  1 
ATOM   12120 C CD1 . LEU D 2 519 ? 159.392 130.419 181.253 1.00 53.18  ? 535 LEU E CD1 1 
ATOM   12121 C CD2 . LEU D 2 519 ? 160.382 132.596 180.553 1.00 50.42  ? 535 LEU E CD2 1 
ATOM   12122 N N   . ALA D 2 520 ? 160.823 133.968 185.594 1.00 50.56  ? 536 ALA E N   1 
ATOM   12123 C CA  . ALA D 2 520 ? 160.519 134.239 186.993 1.00 56.47  ? 536 ALA E CA  1 
ATOM   12124 C C   . ALA D 2 520 ? 159.464 135.333 187.110 1.00 60.62  ? 536 ALA E C   1 
ATOM   12125 O O   . ALA D 2 520 ? 159.105 135.971 186.120 1.00 62.92  ? 536 ALA E O   1 
ATOM   12126 C CB  . ALA D 2 520 ? 161.777 134.634 187.743 1.00 52.28  ? 536 ALA E CB  1 
HETATM 12127 C C1  . IHP E 4 .   ? 164.259 170.670 124.886 1.00 49.55  ? 401 IHP D C1  1 
HETATM 12128 C C2  . IHP E 4 .   ? 163.997 171.321 126.233 1.00 47.60  ? 401 IHP D C2  1 
HETATM 12129 C C3  . IHP E 4 .   ? 162.833 170.626 126.918 1.00 56.83  ? 401 IHP D C3  1 
HETATM 12130 C C4  . IHP E 4 .   ? 161.539 170.916 126.174 1.00 56.32  ? 401 IHP D C4  1 
HETATM 12131 C C5  . IHP E 4 .   ? 161.819 171.208 124.709 1.00 59.39  ? 401 IHP D C5  1 
HETATM 12132 C C6  . IHP E 4 .   ? 162.947 170.327 124.198 1.00 51.80  ? 401 IHP D C6  1 
HETATM 12133 O O11 . IHP E 4 .   ? 165.008 169.454 125.091 1.00 55.49  ? 401 IHP D O11 1 
HETATM 12134 P P1  . IHP E 4 .   ? 166.190 168.798 124.184 1.00 48.91  ? 401 IHP D P1  1 
HETATM 12135 O O21 . IHP E 4 .   ? 167.319 169.802 124.176 1.00 52.26  ? 401 IHP D O21 1 
HETATM 12136 O O31 . IHP E 4 .   ? 166.557 167.506 124.884 1.00 38.41  ? 401 IHP D O31 1 
HETATM 12137 O O41 . IHP E 4 .   ? 165.601 168.566 122.808 1.00 34.56  ? 401 IHP D O41 1 
HETATM 12138 O O12 . IHP E 4 .   ? 165.179 171.207 127.051 1.00 54.34  ? 401 IHP D O12 1 
HETATM 12139 P P2  . IHP E 4 .   ? 166.494 172.164 127.108 1.00 79.43  ? 401 IHP D P2  1 
HETATM 12140 O O22 . IHP E 4 .   ? 166.239 173.158 128.218 1.00 55.67  ? 401 IHP D O22 1 
HETATM 12141 O O32 . IHP E 4 .   ? 167.663 171.244 127.396 1.00 57.62  ? 401 IHP D O32 1 
HETATM 12142 O O42 . IHP E 4 .   ? 166.585 172.813 125.742 1.00 62.24  ? 401 IHP D O42 1 
HETATM 12143 O O13 . IHP E 4 .   ? 162.728 171.098 128.279 1.00 63.45  ? 401 IHP D O13 1 
HETATM 12144 P P3  . IHP E 4 .   ? 162.320 172.547 128.896 1.00 67.70  ? 401 IHP D P3  1 
HETATM 12145 O O23 . IHP E 4 .   ? 163.383 172.837 129.930 1.00 51.68  ? 401 IHP D O23 1 
HETATM 12146 O O33 . IHP E 4 .   ? 160.946 172.353 129.504 1.00 47.34  ? 401 IHP D O33 1 
HETATM 12147 O O43 . IHP E 4 .   ? 162.317 173.545 127.757 1.00 60.39  ? 401 IHP D O43 1 
HETATM 12148 O O14 . IHP E 4 .   ? 160.668 169.767 126.250 1.00 47.35  ? 401 IHP D O14 1 
HETATM 12149 P P4  . IHP E 4 .   ? 159.550 169.418 127.377 1.00 55.63  ? 401 IHP D P4  1 
HETATM 12150 O O24 . IHP E 4 .   ? 159.269 170.730 128.072 1.00 55.21  ? 401 IHP D O24 1 
HETATM 12151 O O34 . IHP E 4 .   ? 158.341 168.865 126.651 1.00 42.31  ? 401 IHP D O34 1 
HETATM 12152 O O44 . IHP E 4 .   ? 160.208 168.397 128.282 1.00 47.96  ? 401 IHP D O44 1 
HETATM 12153 O O15 . IHP E 4 .   ? 160.625 170.921 123.951 1.00 65.63  ? 401 IHP D O15 1 
HETATM 12154 P P5  . IHP E 4 .   ? 159.438 171.948 123.527 1.00 76.43  ? 401 IHP D P5  1 
HETATM 12155 O O25 . IHP E 4 .   ? 160.091 172.975 122.629 1.00 63.49  ? 401 IHP D O25 1 
HETATM 12156 O O35 . IHP E 4 .   ? 158.919 172.539 124.822 1.00 69.93  ? 401 IHP D O35 1 
HETATM 12157 O O45 . IHP E 4 .   ? 158.402 171.107 122.811 1.00 53.89  ? 401 IHP D O45 1 
HETATM 12158 O O16 . IHP E 4 .   ? 163.104 170.565 122.785 1.00 50.81  ? 401 IHP D O16 1 
HETATM 12159 P P6  . IHP E 4 .   ? 162.657 169.642 121.528 1.00 48.74  ? 401 IHP D P6  1 
HETATM 12160 O O26 . IHP E 4 .   ? 163.503 170.144 120.379 1.00 63.65  ? 401 IHP D O26 1 
HETATM 12161 O O36 . IHP E 4 .   ? 162.961 168.210 121.916 1.00 29.67  ? 401 IHP D O36 1 
HETATM 12162 O O46 . IHP E 4 .   ? 161.176 169.893 121.335 1.00 51.14  ? 401 IHP D O46 1 
# 
