data_9DTG
# 
_entry.id   9DTG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DTG         pdb_00009dtg 10.2210/pdb9dtg/pdb 
WWPDB D_1000288743 ?            ?                   
EMDB  EMD-47155    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2024-11-27 ? 
2  'EM metadata'     1 0 2024-11-27 ? 
3  FSC               1 0 2024-11-27 ? 
4  'Half map'        1 0 2024-11-27 1 
5  'Half map'        1 0 2024-11-27 2 
6  Image             1 0 2024-11-27 ? 
7  'Primary map'     1 0 2024-11-27 ? 
8  'Structure model' 1 1 2025-02-12 ? 
9  FSC               1 0 2024-11-27 ? 
10 'Half map'        1 0 2024-11-27 1 
11 'Half map'        1 0 2024-11-27 2 
12 Image             1 0 2024-11-27 ? 
13 'Primary map'     1 0 2024-11-27 ? 
14 'Structure model' 1 2 2025-02-26 ? 
15 'EM metadata'     1 1 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  FSC               repository 'Initial release' ? ? 
4  4  'Half map'        repository 'Initial release' ? ? 
5  5  'Half map'        repository 'Initial release' ? ? 
6  6  Image             repository 'Initial release' ? ? 
7  7  'Primary map'     repository 'Initial release' ? ? 
8  9  FSC               repository 'Initial release' ? ? 
9  10 'Half map'        repository 'Initial release' ? ? 
10 11 'Half map'        repository 'Initial release' ? ? 
11 12 Image             repository 'Initial release' ? ? 
12 13 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8  'Structure model' 'Data collection'      
2 8  'Structure model' 'Database references'  
3 14 'Structure model' 'Data collection'      
4 14 'Structure model' 'Database references'  
5 15 'EM metadata'     'Database references'  
6 15 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8  'Structure model' citation        
2 8  'Structure model' citation_author 
3 8  'Structure model' em_admin        
4 14 'Structure model' citation        
5 14 'Structure model' citation_author 
6 14 'Structure model' em_admin        
7 15 'EM metadata'     citation        
8 15 'EM metadata'     citation_author 
9 15 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  8  'Structure model' '_citation.country'                 
2  8  'Structure model' '_citation.journal_abbrev'          
3  8  'Structure model' '_citation.journal_id_ASTM'         
4  8  'Structure model' '_citation.journal_id_CSD'          
5  8  'Structure model' '_citation.journal_id_ISSN'         
6  8  'Structure model' '_citation.pdbx_database_id_DOI'    
7  8  'Structure model' '_citation.title'                   
8  8  'Structure model' '_citation.year'                    
9  8  'Structure model' '_em_admin.last_update'             
10 14 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 14 'Structure model' '_citation.title'                   
12 14 'Structure model' '_citation_author.identifier_ORCID' 
13 14 'Structure model' '_em_admin.last_update'             
14 15 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
15 15 'EM metadata'     '_citation.title'                   
16 15 'EM metadata'     '_citation_author.identifier_ORCID' 
17 15 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DTG 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'The cryo-EM structure of apo KBTBD4' 
_pdbx_database_related.db_id          EMD-47155 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 nzheng@uw.edu        Ning  Zheng ? 'principal investigator/group leader' 0000-0002-1039-1581 
3 liau@fas.harvard.edu Brian Liau  ? 'principal investigator/group leader' 0000-0002-2985-462X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xie, X.'   1 0000-0002-9884-1865 
'Mao, H.'   2 ?                   
'Liau, B.'  3 0000-0002-2985-462X 
'Zheng, N.' 4 0000-0002-1039-1581 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nature 
_citation.journal_id_ASTM           NATUAS 
_citation.journal_id_CSD            0006 
_citation.journal_id_ISSN           1476-4687 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41586-024-08532-4 
_citation.pdbx_database_id_PubMed   39939761 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yeo, M.J.R.'     1  ? 
primary 'Zhang, O.'       2  ? 
primary 'Xie, X.'         3  ? 
primary 'Nam, E.'         4  ? 
primary 'Payne, N.C.'     5  ? 
primary 'Gosavi, P.M.'    6  ? 
primary 'Kwok, H.S.'      7  ? 
primary 'Iram, I.'        8  ? 
primary 'Lee, C.'         9  ? 
primary 'Li, J.'          10 ? 
primary 'Chen, N.J.'      11 ? 
primary 'Nguyen, K.'      12 ? 
primary 'Jiang, H.'       13 ? 
primary 'Wang, Z.A.'      14 ? 
primary 'Lee, K.'         15 ? 
primary 'Mao, H.'         16 ? 
primary 'Harry, S.A.'     17 ? 
primary 'Barakat, I.A.'   18 ? 
primary 'Takahashi, M.'   19 ? 
primary 'Waterbury, A.L.' 20 ? 
primary 'Barone, M.'      21 ? 
primary 'Mattevi, A.'     22 ? 
primary 'Carr, S.A.'      23 ? 
primary 'Udeshi, N.D.'    24 ? 
primary 'Bar-Peled, L.'   25 ? 
primary 'Cole, P.A.'      26 ? 
primary 'Mazitschek, R.'  27 ? 
primary 'Liau, B.B.'      28 ? 
primary 'Zheng, N.'       29 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Isoform 2 of Kelch repeat and BTB domain-containing protein 4' 
_entity.formula_weight             59971.711 
_entity.pdbx_number_of_molecules   2 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'BTB and kelch domain-containing protein 4' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKGGNADSWQREKLASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLS
AQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQV
GNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFA
ESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNA
TVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLG
GEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAP
SLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKGGNADSWQREKLASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLS
AQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQV
GNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFA
ESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNA
TVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLG
GEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAP
SLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   GLY n 
1 4   GLY n 
1 5   ASN n 
1 6   ALA n 
1 7   ASP n 
1 8   SER n 
1 9   TRP n 
1 10  GLN n 
1 11  ARG n 
1 12  GLU n 
1 13  LYS n 
1 14  LEU n 
1 15  ALA n 
1 16  SER n 
1 17  MET n 
1 18  GLU n 
1 19  SER n 
1 20  PRO n 
1 21  GLU n 
1 22  GLU n 
1 23  PRO n 
1 24  GLY n 
1 25  ALA n 
1 26  SER n 
1 27  MET n 
1 28  ASP n 
1 29  GLU n 
1 30  ASN n 
1 31  TYR n 
1 32  PHE n 
1 33  VAL n 
1 34  ASN n 
1 35  TYR n 
1 36  THR n 
1 37  PHE n 
1 38  LYS n 
1 39  ASP n 
1 40  ARG n 
1 41  SER n 
1 42  HIS n 
1 43  SER n 
1 44  GLY n 
1 45  ARG n 
1 46  VAL n 
1 47  ALA n 
1 48  GLN n 
1 49  GLY n 
1 50  ILE n 
1 51  MET n 
1 52  LYS n 
1 53  LEU n 
1 54  CYS n 
1 55  LEU n 
1 56  GLU n 
1 57  GLU n 
1 58  GLU n 
1 59  LEU n 
1 60  PHE n 
1 61  ALA n 
1 62  ASP n 
1 63  VAL n 
1 64  THR n 
1 65  ILE n 
1 66  SER n 
1 67  VAL n 
1 68  GLU n 
1 69  GLY n 
1 70  ARG n 
1 71  GLU n 
1 72  PHE n 
1 73  GLN n 
1 74  LEU n 
1 75  HIS n 
1 76  ARG n 
1 77  LEU n 
1 78  VAL n 
1 79  LEU n 
1 80  SER n 
1 81  ALA n 
1 82  GLN n 
1 83  SER n 
1 84  CYS n 
1 85  PHE n 
1 86  PHE n 
1 87  ARG n 
1 88  SER n 
1 89  MET n 
1 90  PHE n 
1 91  THR n 
1 92  SER n 
1 93  ASN n 
1 94  LEU n 
1 95  LYS n 
1 96  GLU n 
1 97  ALA n 
1 98  HIS n 
1 99  ASN n 
1 100 ARG n 
1 101 VAL n 
1 102 ILE n 
1 103 VAL n 
1 104 LEU n 
1 105 GLN n 
1 106 ASP n 
1 107 VAL n 
1 108 SER n 
1 109 GLU n 
1 110 SER n 
1 111 VAL n 
1 112 PHE n 
1 113 GLN n 
1 114 LEU n 
1 115 LEU n 
1 116 VAL n 
1 117 ASP n 
1 118 TYR n 
1 119 ILE n 
1 120 TYR n 
1 121 HIS n 
1 122 GLY n 
1 123 THR n 
1 124 VAL n 
1 125 LYS n 
1 126 LEU n 
1 127 ARG n 
1 128 ALA n 
1 129 GLU n 
1 130 GLU n 
1 131 LEU n 
1 132 GLN n 
1 133 GLU n 
1 134 ILE n 
1 135 TYR n 
1 136 GLU n 
1 137 VAL n 
1 138 SER n 
1 139 ASP n 
1 140 MET n 
1 141 TYR n 
1 142 GLN n 
1 143 LEU n 
1 144 THR n 
1 145 SER n 
1 146 LEU n 
1 147 PHE n 
1 148 GLU n 
1 149 GLU n 
1 150 CYS n 
1 151 SER n 
1 152 ARG n 
1 153 PHE n 
1 154 LEU n 
1 155 ALA n 
1 156 ARG n 
1 157 THR n 
1 158 VAL n 
1 159 GLN n 
1 160 VAL n 
1 161 GLY n 
1 162 ASN n 
1 163 CYS n 
1 164 LEU n 
1 165 GLN n 
1 166 VAL n 
1 167 MET n 
1 168 TRP n 
1 169 LEU n 
1 170 ALA n 
1 171 ASP n 
1 172 ARG n 
1 173 HIS n 
1 174 SER n 
1 175 ASP n 
1 176 PRO n 
1 177 GLU n 
1 178 LEU n 
1 179 TYR n 
1 180 THR n 
1 181 ALA n 
1 182 ALA n 
1 183 LYS n 
1 184 HIS n 
1 185 CYS n 
1 186 ALA n 
1 187 LYS n 
1 188 THR n 
1 189 HIS n 
1 190 LEU n 
1 191 ALA n 
1 192 GLN n 
1 193 LEU n 
1 194 GLN n 
1 195 ASN n 
1 196 THR n 
1 197 GLU n 
1 198 GLU n 
1 199 PHE n 
1 200 LEU n 
1 201 HIS n 
1 202 LEU n 
1 203 PRO n 
1 204 HIS n 
1 205 ARG n 
1 206 LEU n 
1 207 LEU n 
1 208 THR n 
1 209 ASP n 
1 210 ILE n 
1 211 ILE n 
1 212 SER n 
1 213 ASP n 
1 214 GLY n 
1 215 VAL n 
1 216 PRO n 
1 217 CYS n 
1 218 SER n 
1 219 GLN n 
1 220 ASN n 
1 221 PRO n 
1 222 THR n 
1 223 GLU n 
1 224 ALA n 
1 225 ILE n 
1 226 GLU n 
1 227 ALA n 
1 228 TRP n 
1 229 ILE n 
1 230 ASN n 
1 231 PHE n 
1 232 ASN n 
1 233 LYS n 
1 234 GLU n 
1 235 GLU n 
1 236 ARG n 
1 237 GLU n 
1 238 ALA n 
1 239 PHE n 
1 240 ALA n 
1 241 GLU n 
1 242 SER n 
1 243 LEU n 
1 244 ARG n 
1 245 THR n 
1 246 SER n 
1 247 LEU n 
1 248 LYS n 
1 249 GLU n 
1 250 ILE n 
1 251 GLY n 
1 252 GLU n 
1 253 ASN n 
1 254 VAL n 
1 255 HIS n 
1 256 ILE n 
1 257 TYR n 
1 258 LEU n 
1 259 ILE n 
1 260 GLY n 
1 261 LYS n 
1 262 GLU n 
1 263 SER n 
1 264 SER n 
1 265 ARG n 
1 266 THR n 
1 267 HIS n 
1 268 SER n 
1 269 LEU n 
1 270 ALA n 
1 271 VAL n 
1 272 SER n 
1 273 LEU n 
1 274 HIS n 
1 275 CYS n 
1 276 ALA n 
1 277 GLU n 
1 278 ASP n 
1 279 ASP n 
1 280 SER n 
1 281 ILE n 
1 282 SER n 
1 283 VAL n 
1 284 SER n 
1 285 GLY n 
1 286 GLN n 
1 287 ASN n 
1 288 SER n 
1 289 LEU n 
1 290 CYS n 
1 291 HIS n 
1 292 GLN n 
1 293 ILE n 
1 294 THR n 
1 295 ALA n 
1 296 ALA n 
1 297 CYS n 
1 298 LYS n 
1 299 HIS n 
1 300 GLY n 
1 301 GLY n 
1 302 ASP n 
1 303 LEU n 
1 304 TYR n 
1 305 VAL n 
1 306 VAL n 
1 307 GLY n 
1 308 GLY n 
1 309 SER n 
1 310 ILE n 
1 311 PRO n 
1 312 ARG n 
1 313 ARG n 
1 314 MET n 
1 315 TRP n 
1 316 LYS n 
1 317 CYS n 
1 318 ASN n 
1 319 ASN n 
1 320 ALA n 
1 321 THR n 
1 322 VAL n 
1 323 ASP n 
1 324 TRP n 
1 325 GLU n 
1 326 TRP n 
1 327 CYS n 
1 328 ALA n 
1 329 PRO n 
1 330 LEU n 
1 331 PRO n 
1 332 ARG n 
1 333 ASP n 
1 334 ARG n 
1 335 LEU n 
1 336 GLN n 
1 337 HIS n 
1 338 THR n 
1 339 LEU n 
1 340 VAL n 
1 341 SER n 
1 342 VAL n 
1 343 PRO n 
1 344 GLY n 
1 345 LYS n 
1 346 ASP n 
1 347 ALA n 
1 348 ILE n 
1 349 TYR n 
1 350 SER n 
1 351 LEU n 
1 352 GLY n 
1 353 GLY n 
1 354 LYS n 
1 355 THR n 
1 356 LEU n 
1 357 GLN n 
1 358 ASP n 
1 359 THR n 
1 360 LEU n 
1 361 SER n 
1 362 ASN n 
1 363 ALA n 
1 364 VAL n 
1 365 ILE n 
1 366 TYR n 
1 367 TYR n 
1 368 ARG n 
1 369 VAL n 
1 370 GLY n 
1 371 ASP n 
1 372 ASN n 
1 373 VAL n 
1 374 TRP n 
1 375 THR n 
1 376 GLU n 
1 377 THR n 
1 378 THR n 
1 379 GLN n 
1 380 LEU n 
1 381 GLU n 
1 382 VAL n 
1 383 ALA n 
1 384 VAL n 
1 385 SER n 
1 386 GLY n 
1 387 ALA n 
1 388 ALA n 
1 389 GLY n 
1 390 ALA n 
1 391 ASN n 
1 392 LEU n 
1 393 ASN n 
1 394 GLY n 
1 395 ILE n 
1 396 ILE n 
1 397 TYR n 
1 398 LEU n 
1 399 LEU n 
1 400 GLY n 
1 401 GLY n 
1 402 GLU n 
1 403 GLU n 
1 404 ASN n 
1 405 ASP n 
1 406 LEU n 
1 407 ASP n 
1 408 PHE n 
1 409 PHE n 
1 410 THR n 
1 411 LYS n 
1 412 PRO n 
1 413 SER n 
1 414 ARG n 
1 415 LEU n 
1 416 ILE n 
1 417 GLN n 
1 418 CYS n 
1 419 PHE n 
1 420 ASP n 
1 421 THR n 
1 422 GLU n 
1 423 THR n 
1 424 ASP n 
1 425 LYS n 
1 426 CYS n 
1 427 HIS n 
1 428 VAL n 
1 429 LYS n 
1 430 PRO n 
1 431 TYR n 
1 432 VAL n 
1 433 LEU n 
1 434 PRO n 
1 435 PHE n 
1 436 ALA n 
1 437 GLY n 
1 438 ARG n 
1 439 MET n 
1 440 HIS n 
1 441 ALA n 
1 442 ALA n 
1 443 VAL n 
1 444 HIS n 
1 445 LYS n 
1 446 ASP n 
1 447 LEU n 
1 448 VAL n 
1 449 PHE n 
1 450 ILE n 
1 451 VAL n 
1 452 ALA n 
1 453 GLU n 
1 454 GLY n 
1 455 ASP n 
1 456 SER n 
1 457 LEU n 
1 458 VAL n 
1 459 CYS n 
1 460 TYR n 
1 461 ASN n 
1 462 PRO n 
1 463 LEU n 
1 464 LEU n 
1 465 ASP n 
1 466 SER n 
1 467 PHE n 
1 468 THR n 
1 469 ARG n 
1 470 LEU n 
1 471 CYS n 
1 472 LEU n 
1 473 PRO n 
1 474 GLU n 
1 475 ALA n 
1 476 TRP n 
1 477 SER n 
1 478 SER n 
1 479 ALA n 
1 480 PRO n 
1 481 SER n 
1 482 LEU n 
1 483 TRP n 
1 484 LYS n 
1 485 ILE n 
1 486 ALA n 
1 487 SER n 
1 488 CYS n 
1 489 ASN n 
1 490 GLY n 
1 491 SER n 
1 492 ILE n 
1 493 TYR n 
1 494 VAL n 
1 495 PHE n 
1 496 ARG n 
1 497 ASP n 
1 498 ARG n 
1 499 TYR n 
1 500 LYS n 
1 501 LYS n 
1 502 GLY n 
1 503 ASP n 
1 504 ALA n 
1 505 ASN n 
1 506 THR n 
1 507 TYR n 
1 508 LYS n 
1 509 LEU n 
1 510 ASP n 
1 511 PRO n 
1 512 ALA n 
1 513 THR n 
1 514 SER n 
1 515 ALA n 
1 516 VAL n 
1 517 THR n 
1 518 VAL n 
1 519 THR n 
1 520 ARG n 
1 521 GLY n 
1 522 ILE n 
1 523 LYS n 
1 524 VAL n 
1 525 LEU n 
1 526 LEU n 
1 527 THR n 
1 528 ASN n 
1 529 LEU n 
1 530 GLN n 
1 531 PHE n 
1 532 VAL n 
1 533 LEU n 
1 534 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   534 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'KBTBD4, BKLHD4' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               'cabbage looper' 
_entity_src_gen.pdbx_host_org_scientific_name      'Trichoplusia ni' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7111 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -15 ?   ?   ?   A . n 
A 1 2   LYS 2   -14 ?   ?   ?   A . n 
A 1 3   GLY 3   -13 ?   ?   ?   A . n 
A 1 4   GLY 4   -12 ?   ?   ?   A . n 
A 1 5   ASN 5   -11 ?   ?   ?   A . n 
A 1 6   ALA 6   -10 ?   ?   ?   A . n 
A 1 7   ASP 7   -9  ?   ?   ?   A . n 
A 1 8   SER 8   -8  ?   ?   ?   A . n 
A 1 9   TRP 9   -7  ?   ?   ?   A . n 
A 1 10  GLN 10  -6  ?   ?   ?   A . n 
A 1 11  ARG 11  -5  ?   ?   ?   A . n 
A 1 12  GLU 12  -4  ?   ?   ?   A . n 
A 1 13  LYS 13  -3  ?   ?   ?   A . n 
A 1 14  LEU 14  -2  ?   ?   ?   A . n 
A 1 15  ALA 15  -1  ?   ?   ?   A . n 
A 1 16  SER 16  0   ?   ?   ?   A . n 
A 1 17  MET 17  1   ?   ?   ?   A . n 
A 1 18  GLU 18  2   ?   ?   ?   A . n 
A 1 19  SER 19  3   ?   ?   ?   A . n 
A 1 20  PRO 20  4   ?   ?   ?   A . n 
A 1 21  GLU 21  5   ?   ?   ?   A . n 
A 1 22  GLU 22  6   ?   ?   ?   A . n 
A 1 23  PRO 23  7   7   PRO PRO A . n 
A 1 24  GLY 24  8   8   GLY GLY A . n 
A 1 25  ALA 25  9   9   ALA ALA A . n 
A 1 26  SER 26  10  10  SER SER A . n 
A 1 27  MET 27  11  11  MET MET A . n 
A 1 28  ASP 28  12  12  ASP ASP A . n 
A 1 29  GLU 29  13  13  GLU GLU A . n 
A 1 30  ASN 30  14  14  ASN ASN A . n 
A 1 31  TYR 31  15  15  TYR TYR A . n 
A 1 32  PHE 32  16  16  PHE PHE A . n 
A 1 33  VAL 33  17  17  VAL VAL A . n 
A 1 34  ASN 34  18  18  ASN ASN A . n 
A 1 35  TYR 35  19  19  TYR TYR A . n 
A 1 36  THR 36  20  20  THR THR A . n 
A 1 37  PHE 37  21  21  PHE PHE A . n 
A 1 38  LYS 38  22  22  LYS LYS A . n 
A 1 39  ASP 39  23  23  ASP ASP A . n 
A 1 40  ARG 40  24  24  ARG ARG A . n 
A 1 41  SER 41  25  25  SER SER A . n 
A 1 42  HIS 42  26  26  HIS HIS A . n 
A 1 43  SER 43  27  27  SER SER A . n 
A 1 44  GLY 44  28  28  GLY GLY A . n 
A 1 45  ARG 45  29  29  ARG ARG A . n 
A 1 46  VAL 46  30  30  VAL VAL A . n 
A 1 47  ALA 47  31  31  ALA ALA A . n 
A 1 48  GLN 48  32  32  GLN GLN A . n 
A 1 49  GLY 49  33  33  GLY GLY A . n 
A 1 50  ILE 50  34  34  ILE ILE A . n 
A 1 51  MET 51  35  35  MET MET A . n 
A 1 52  LYS 52  36  36  LYS LYS A . n 
A 1 53  LEU 53  37  37  LEU LEU A . n 
A 1 54  CYS 54  38  38  CYS CYS A . n 
A 1 55  LEU 55  39  39  LEU LEU A . n 
A 1 56  GLU 56  40  40  GLU GLU A . n 
A 1 57  GLU 57  41  41  GLU GLU A . n 
A 1 58  GLU 58  42  42  GLU GLU A . n 
A 1 59  LEU 59  43  43  LEU LEU A . n 
A 1 60  PHE 60  44  44  PHE PHE A . n 
A 1 61  ALA 61  45  45  ALA ALA A . n 
A 1 62  ASP 62  46  46  ASP ASP A . n 
A 1 63  VAL 63  47  47  VAL VAL A . n 
A 1 64  THR 64  48  48  THR THR A . n 
A 1 65  ILE 65  49  49  ILE ILE A . n 
A 1 66  SER 66  50  50  SER SER A . n 
A 1 67  VAL 67  51  51  VAL VAL A . n 
A 1 68  GLU 68  52  52  GLU GLU A . n 
A 1 69  GLY 69  53  53  GLY GLY A . n 
A 1 70  ARG 70  54  54  ARG ARG A . n 
A 1 71  GLU 71  55  55  GLU GLU A . n 
A 1 72  PHE 72  56  56  PHE PHE A . n 
A 1 73  GLN 73  57  57  GLN GLN A . n 
A 1 74  LEU 74  58  58  LEU LEU A . n 
A 1 75  HIS 75  59  59  HIS HIS A . n 
A 1 76  ARG 76  60  60  ARG ARG A . n 
A 1 77  LEU 77  61  61  LEU LEU A . n 
A 1 78  VAL 78  62  62  VAL VAL A . n 
A 1 79  LEU 79  63  63  LEU LEU A . n 
A 1 80  SER 80  64  64  SER SER A . n 
A 1 81  ALA 81  65  65  ALA ALA A . n 
A 1 82  GLN 82  66  66  GLN GLN A . n 
A 1 83  SER 83  67  67  SER SER A . n 
A 1 84  CYS 84  68  68  CYS CYS A . n 
A 1 85  PHE 85  69  69  PHE PHE A . n 
A 1 86  PHE 86  70  70  PHE PHE A . n 
A 1 87  ARG 87  71  71  ARG ARG A . n 
A 1 88  SER 88  72  72  SER SER A . n 
A 1 89  MET 89  73  73  MET MET A . n 
A 1 90  PHE 90  74  74  PHE PHE A . n 
A 1 91  THR 91  75  75  THR THR A . n 
A 1 92  SER 92  76  76  SER SER A . n 
A 1 93  ASN 93  77  77  ASN ASN A . n 
A 1 94  LEU 94  78  78  LEU LEU A . n 
A 1 95  LYS 95  79  79  LYS LYS A . n 
A 1 96  GLU 96  80  80  GLU GLU A . n 
A 1 97  ALA 97  81  81  ALA ALA A . n 
A 1 98  HIS 98  82  82  HIS HIS A . n 
A 1 99  ASN 99  83  83  ASN ASN A . n 
A 1 100 ARG 100 84  84  ARG ARG A . n 
A 1 101 VAL 101 85  85  VAL VAL A . n 
A 1 102 ILE 102 86  86  ILE ILE A . n 
A 1 103 VAL 103 87  87  VAL VAL A . n 
A 1 104 LEU 104 88  88  LEU LEU A . n 
A 1 105 GLN 105 89  89  GLN GLN A . n 
A 1 106 ASP 106 90  90  ASP ASP A . n 
A 1 107 VAL 107 91  91  VAL VAL A . n 
A 1 108 SER 108 92  92  SER SER A . n 
A 1 109 GLU 109 93  93  GLU GLU A . n 
A 1 110 SER 110 94  94  SER SER A . n 
A 1 111 VAL 111 95  95  VAL VAL A . n 
A 1 112 PHE 112 96  96  PHE PHE A . n 
A 1 113 GLN 113 97  97  GLN GLN A . n 
A 1 114 LEU 114 98  98  LEU LEU A . n 
A 1 115 LEU 115 99  99  LEU LEU A . n 
A 1 116 VAL 116 100 100 VAL VAL A . n 
A 1 117 ASP 117 101 101 ASP ASP A . n 
A 1 118 TYR 118 102 102 TYR TYR A . n 
A 1 119 ILE 119 103 103 ILE ILE A . n 
A 1 120 TYR 120 104 104 TYR TYR A . n 
A 1 121 HIS 121 105 105 HIS HIS A . n 
A 1 122 GLY 122 106 106 GLY GLY A . n 
A 1 123 THR 123 107 107 THR THR A . n 
A 1 124 VAL 124 108 108 VAL VAL A . n 
A 1 125 LYS 125 109 109 LYS LYS A . n 
A 1 126 LEU 126 110 110 LEU LEU A . n 
A 1 127 ARG 127 111 111 ARG ARG A . n 
A 1 128 ALA 128 112 112 ALA ALA A . n 
A 1 129 GLU 129 113 113 GLU GLU A . n 
A 1 130 GLU 130 114 114 GLU GLU A . n 
A 1 131 LEU 131 115 115 LEU LEU A . n 
A 1 132 GLN 132 116 116 GLN GLN A . n 
A 1 133 GLU 133 117 117 GLU GLU A . n 
A 1 134 ILE 134 118 118 ILE ILE A . n 
A 1 135 TYR 135 119 119 TYR TYR A . n 
A 1 136 GLU 136 120 120 GLU GLU A . n 
A 1 137 VAL 137 121 121 VAL VAL A . n 
A 1 138 SER 138 122 122 SER SER A . n 
A 1 139 ASP 139 123 123 ASP ASP A . n 
A 1 140 MET 140 124 124 MET MET A . n 
A 1 141 TYR 141 125 125 TYR TYR A . n 
A 1 142 GLN 142 126 126 GLN GLN A . n 
A 1 143 LEU 143 127 127 LEU LEU A . n 
A 1 144 THR 144 128 128 THR THR A . n 
A 1 145 SER 145 129 129 SER SER A . n 
A 1 146 LEU 146 130 130 LEU LEU A . n 
A 1 147 PHE 147 131 131 PHE PHE A . n 
A 1 148 GLU 148 132 132 GLU GLU A . n 
A 1 149 GLU 149 133 133 GLU GLU A . n 
A 1 150 CYS 150 134 134 CYS CYS A . n 
A 1 151 SER 151 135 135 SER SER A . n 
A 1 152 ARG 152 136 136 ARG ARG A . n 
A 1 153 PHE 153 137 137 PHE PHE A . n 
A 1 154 LEU 154 138 138 LEU LEU A . n 
A 1 155 ALA 155 139 139 ALA ALA A . n 
A 1 156 ARG 156 140 140 ARG ARG A . n 
A 1 157 THR 157 141 141 THR THR A . n 
A 1 158 VAL 158 142 142 VAL VAL A . n 
A 1 159 GLN 159 143 143 GLN GLN A . n 
A 1 160 VAL 160 144 144 VAL VAL A . n 
A 1 161 GLY 161 145 145 GLY GLY A . n 
A 1 162 ASN 162 146 146 ASN ASN A . n 
A 1 163 CYS 163 147 147 CYS CYS A . n 
A 1 164 LEU 164 148 148 LEU LEU A . n 
A 1 165 GLN 165 149 149 GLN GLN A . n 
A 1 166 VAL 166 150 150 VAL VAL A . n 
A 1 167 MET 167 151 151 MET MET A . n 
A 1 168 TRP 168 152 152 TRP TRP A . n 
A 1 169 LEU 169 153 153 LEU LEU A . n 
A 1 170 ALA 170 154 154 ALA ALA A . n 
A 1 171 ASP 171 155 155 ASP ASP A . n 
A 1 172 ARG 172 156 156 ARG ARG A . n 
A 1 173 HIS 173 157 157 HIS HIS A . n 
A 1 174 SER 174 158 158 SER SER A . n 
A 1 175 ASP 175 159 159 ASP ASP A . n 
A 1 176 PRO 176 160 160 PRO PRO A . n 
A 1 177 GLU 177 161 161 GLU GLU A . n 
A 1 178 LEU 178 162 162 LEU LEU A . n 
A 1 179 TYR 179 163 163 TYR TYR A . n 
A 1 180 THR 180 164 164 THR THR A . n 
A 1 181 ALA 181 165 165 ALA ALA A . n 
A 1 182 ALA 182 166 166 ALA ALA A . n 
A 1 183 LYS 183 167 167 LYS LYS A . n 
A 1 184 HIS 184 168 168 HIS HIS A . n 
A 1 185 CYS 185 169 169 CYS CYS A . n 
A 1 186 ALA 186 170 170 ALA ALA A . n 
A 1 187 LYS 187 171 171 LYS LYS A . n 
A 1 188 THR 188 172 172 THR THR A . n 
A 1 189 HIS 189 173 173 HIS HIS A . n 
A 1 190 LEU 190 174 174 LEU LEU A . n 
A 1 191 ALA 191 175 175 ALA ALA A . n 
A 1 192 GLN 192 176 176 GLN GLN A . n 
A 1 193 LEU 193 177 177 LEU LEU A . n 
A 1 194 GLN 194 178 178 GLN GLN A . n 
A 1 195 ASN 195 179 179 ASN ASN A . n 
A 1 196 THR 196 180 180 THR THR A . n 
A 1 197 GLU 197 181 181 GLU GLU A . n 
A 1 198 GLU 198 182 182 GLU GLU A . n 
A 1 199 PHE 199 183 183 PHE PHE A . n 
A 1 200 LEU 200 184 184 LEU LEU A . n 
A 1 201 HIS 201 185 185 HIS HIS A . n 
A 1 202 LEU 202 186 186 LEU LEU A . n 
A 1 203 PRO 203 187 187 PRO PRO A . n 
A 1 204 HIS 204 188 188 HIS HIS A . n 
A 1 205 ARG 205 189 189 ARG ARG A . n 
A 1 206 LEU 206 190 190 LEU LEU A . n 
A 1 207 LEU 207 191 191 LEU LEU A . n 
A 1 208 THR 208 192 192 THR THR A . n 
A 1 209 ASP 209 193 193 ASP ASP A . n 
A 1 210 ILE 210 194 194 ILE ILE A . n 
A 1 211 ILE 211 195 195 ILE ILE A . n 
A 1 212 SER 212 196 196 SER SER A . n 
A 1 213 ASP 213 197 197 ASP ASP A . n 
A 1 214 GLY 214 198 198 GLY GLY A . n 
A 1 215 VAL 215 199 199 VAL VAL A . n 
A 1 216 PRO 216 200 200 PRO PRO A . n 
A 1 217 CYS 217 201 201 CYS CYS A . n 
A 1 218 SER 218 202 202 SER SER A . n 
A 1 219 GLN 219 203 203 GLN GLN A . n 
A 1 220 ASN 220 204 204 ASN ASN A . n 
A 1 221 PRO 221 205 205 PRO PRO A . n 
A 1 222 THR 222 206 206 THR THR A . n 
A 1 223 GLU 223 207 207 GLU GLU A . n 
A 1 224 ALA 224 208 208 ALA ALA A . n 
A 1 225 ILE 225 209 209 ILE ILE A . n 
A 1 226 GLU 226 210 210 GLU GLU A . n 
A 1 227 ALA 227 211 211 ALA ALA A . n 
A 1 228 TRP 228 212 212 TRP TRP A . n 
A 1 229 ILE 229 213 213 ILE ILE A . n 
A 1 230 ASN 230 214 214 ASN ASN A . n 
A 1 231 PHE 231 215 215 PHE PHE A . n 
A 1 232 ASN 232 216 216 ASN ASN A . n 
A 1 233 LYS 233 217 217 LYS LYS A . n 
A 1 234 GLU 234 218 218 GLU GLU A . n 
A 1 235 GLU 235 219 219 GLU GLU A . n 
A 1 236 ARG 236 220 220 ARG ARG A . n 
A 1 237 GLU 237 221 221 GLU GLU A . n 
A 1 238 ALA 238 222 222 ALA ALA A . n 
A 1 239 PHE 239 223 223 PHE PHE A . n 
A 1 240 ALA 240 224 224 ALA ALA A . n 
A 1 241 GLU 241 225 225 GLU GLU A . n 
A 1 242 SER 242 226 226 SER SER A . n 
A 1 243 LEU 243 227 227 LEU LEU A . n 
A 1 244 ARG 244 228 228 ARG ARG A . n 
A 1 245 THR 245 229 229 THR THR A . n 
A 1 246 SER 246 230 230 SER SER A . n 
A 1 247 LEU 247 231 231 LEU LEU A . n 
A 1 248 LYS 248 232 232 LYS LYS A . n 
A 1 249 GLU 249 233 233 GLU GLU A . n 
A 1 250 ILE 250 234 234 ILE ILE A . n 
A 1 251 GLY 251 235 235 GLY GLY A . n 
A 1 252 GLU 252 236 236 GLU GLU A . n 
A 1 253 ASN 253 237 237 ASN ASN A . n 
A 1 254 VAL 254 238 238 VAL VAL A . n 
A 1 255 HIS 255 239 239 HIS HIS A . n 
A 1 256 ILE 256 240 240 ILE ILE A . n 
A 1 257 TYR 257 241 241 TYR TYR A . n 
A 1 258 LEU 258 242 242 LEU LEU A . n 
A 1 259 ILE 259 243 243 ILE ILE A . n 
A 1 260 GLY 260 244 244 GLY GLY A . n 
A 1 261 LYS 261 245 245 LYS LYS A . n 
A 1 262 GLU 262 246 246 GLU GLU A . n 
A 1 263 SER 263 247 247 SER SER A . n 
A 1 264 SER 264 248 248 SER SER A . n 
A 1 265 ARG 265 249 249 ARG ARG A . n 
A 1 266 THR 266 250 250 THR THR A . n 
A 1 267 HIS 267 251 251 HIS HIS A . n 
A 1 268 SER 268 252 252 SER SER A . n 
A 1 269 LEU 269 253 253 LEU LEU A . n 
A 1 270 ALA 270 254 254 ALA ALA A . n 
A 1 271 VAL 271 255 255 VAL VAL A . n 
A 1 272 SER 272 256 256 SER SER A . n 
A 1 273 LEU 273 257 257 LEU LEU A . n 
A 1 274 HIS 274 258 258 HIS HIS A . n 
A 1 275 CYS 275 259 259 CYS CYS A . n 
A 1 276 ALA 276 260 260 ALA ALA A . n 
A 1 277 GLU 277 261 261 GLU GLU A . n 
A 1 278 ASP 278 262 262 ASP ASP A . n 
A 1 279 ASP 279 263 263 ASP ASP A . n 
A 1 280 SER 280 264 264 SER SER A . n 
A 1 281 ILE 281 265 265 ILE ILE A . n 
A 1 282 SER 282 266 266 SER SER A . n 
A 1 283 VAL 283 267 267 VAL VAL A . n 
A 1 284 SER 284 268 268 SER SER A . n 
A 1 285 GLY 285 269 269 GLY GLY A . n 
A 1 286 GLN 286 270 270 GLN GLN A . n 
A 1 287 ASN 287 271 271 ASN ASN A . n 
A 1 288 SER 288 272 272 SER SER A . n 
A 1 289 LEU 289 273 273 LEU LEU A . n 
A 1 290 CYS 290 274 274 CYS CYS A . n 
A 1 291 HIS 291 275 275 HIS HIS A . n 
A 1 292 GLN 292 276 276 GLN GLN A . n 
A 1 293 ILE 293 277 277 ILE ILE A . n 
A 1 294 THR 294 278 278 THR THR A . n 
A 1 295 ALA 295 279 279 ALA ALA A . n 
A 1 296 ALA 296 280 280 ALA ALA A . n 
A 1 297 CYS 297 281 281 CYS CYS A . n 
A 1 298 LYS 298 282 282 LYS LYS A . n 
A 1 299 HIS 299 283 283 HIS HIS A . n 
A 1 300 GLY 300 284 284 GLY GLY A . n 
A 1 301 GLY 301 285 285 GLY GLY A . n 
A 1 302 ASP 302 286 286 ASP ASP A . n 
A 1 303 LEU 303 287 287 LEU LEU A . n 
A 1 304 TYR 304 288 288 TYR TYR A . n 
A 1 305 VAL 305 289 289 VAL VAL A . n 
A 1 306 VAL 306 290 290 VAL VAL A . n 
A 1 307 GLY 307 291 291 GLY GLY A . n 
A 1 308 GLY 308 292 292 GLY GLY A . n 
A 1 309 SER 309 293 293 SER SER A . n 
A 1 310 ILE 310 294 294 ILE ILE A . n 
A 1 311 PRO 311 295 295 PRO PRO A . n 
A 1 312 ARG 312 296 296 ARG ARG A . n 
A 1 313 ARG 313 297 297 ARG ARG A . n 
A 1 314 MET 314 298 298 MET MET A . n 
A 1 315 TRP 315 299 299 TRP TRP A . n 
A 1 316 LYS 316 300 300 LYS LYS A . n 
A 1 317 CYS 317 301 301 CYS CYS A . n 
A 1 318 ASN 318 302 302 ASN ASN A . n 
A 1 319 ASN 319 303 303 ASN ASN A . n 
A 1 320 ALA 320 304 304 ALA ALA A . n 
A 1 321 THR 321 305 305 THR THR A . n 
A 1 322 VAL 322 306 306 VAL VAL A . n 
A 1 323 ASP 323 307 307 ASP ASP A . n 
A 1 324 TRP 324 308 308 TRP TRP A . n 
A 1 325 GLU 325 309 309 GLU GLU A . n 
A 1 326 TRP 326 310 310 TRP TRP A . n 
A 1 327 CYS 327 311 311 CYS CYS A . n 
A 1 328 ALA 328 312 312 ALA ALA A . n 
A 1 329 PRO 329 313 313 PRO PRO A . n 
A 1 330 LEU 330 314 314 LEU LEU A . n 
A 1 331 PRO 331 315 315 PRO PRO A . n 
A 1 332 ARG 332 316 316 ARG ARG A . n 
A 1 333 ASP 333 317 317 ASP ASP A . n 
A 1 334 ARG 334 318 318 ARG ARG A . n 
A 1 335 LEU 335 319 319 LEU LEU A . n 
A 1 336 GLN 336 320 320 GLN GLN A . n 
A 1 337 HIS 337 321 321 HIS HIS A . n 
A 1 338 THR 338 322 322 THR THR A . n 
A 1 339 LEU 339 323 323 LEU LEU A . n 
A 1 340 VAL 340 324 324 VAL VAL A . n 
A 1 341 SER 341 325 325 SER SER A . n 
A 1 342 VAL 342 326 326 VAL VAL A . n 
A 1 343 PRO 343 327 327 PRO PRO A . n 
A 1 344 GLY 344 328 328 GLY GLY A . n 
A 1 345 LYS 345 329 329 LYS LYS A . n 
A 1 346 ASP 346 330 330 ASP ASP A . n 
A 1 347 ALA 347 331 331 ALA ALA A . n 
A 1 348 ILE 348 332 332 ILE ILE A . n 
A 1 349 TYR 349 333 333 TYR TYR A . n 
A 1 350 SER 350 334 334 SER SER A . n 
A 1 351 LEU 351 335 335 LEU LEU A . n 
A 1 352 GLY 352 336 336 GLY GLY A . n 
A 1 353 GLY 353 337 337 GLY GLY A . n 
A 1 354 LYS 354 338 338 LYS LYS A . n 
A 1 355 THR 355 339 339 THR THR A . n 
A 1 356 LEU 356 340 340 LEU LEU A . n 
A 1 357 GLN 357 341 341 GLN GLN A . n 
A 1 358 ASP 358 342 342 ASP ASP A . n 
A 1 359 THR 359 343 343 THR THR A . n 
A 1 360 LEU 360 344 344 LEU LEU A . n 
A 1 361 SER 361 345 345 SER SER A . n 
A 1 362 ASN 362 346 346 ASN ASN A . n 
A 1 363 ALA 363 347 347 ALA ALA A . n 
A 1 364 VAL 364 348 348 VAL VAL A . n 
A 1 365 ILE 365 349 349 ILE ILE A . n 
A 1 366 TYR 366 350 350 TYR TYR A . n 
A 1 367 TYR 367 351 351 TYR TYR A . n 
A 1 368 ARG 368 352 352 ARG ARG A . n 
A 1 369 VAL 369 353 353 VAL VAL A . n 
A 1 370 GLY 370 354 354 GLY GLY A . n 
A 1 371 ASP 371 355 355 ASP ASP A . n 
A 1 372 ASN 372 356 356 ASN ASN A . n 
A 1 373 VAL 373 357 357 VAL VAL A . n 
A 1 374 TRP 374 358 358 TRP TRP A . n 
A 1 375 THR 375 359 359 THR THR A . n 
A 1 376 GLU 376 360 360 GLU GLU A . n 
A 1 377 THR 377 361 361 THR THR A . n 
A 1 378 THR 378 362 362 THR THR A . n 
A 1 379 GLN 379 363 363 GLN GLN A . n 
A 1 380 LEU 380 364 364 LEU LEU A . n 
A 1 381 GLU 381 365 365 GLU GLU A . n 
A 1 382 VAL 382 366 366 VAL VAL A . n 
A 1 383 ALA 383 367 367 ALA ALA A . n 
A 1 384 VAL 384 368 368 VAL VAL A . n 
A 1 385 SER 385 369 369 SER SER A . n 
A 1 386 GLY 386 370 370 GLY GLY A . n 
A 1 387 ALA 387 371 371 ALA ALA A . n 
A 1 388 ALA 388 372 372 ALA ALA A . n 
A 1 389 GLY 389 373 373 GLY GLY A . n 
A 1 390 ALA 390 374 374 ALA ALA A . n 
A 1 391 ASN 391 375 375 ASN ASN A . n 
A 1 392 LEU 392 376 376 LEU LEU A . n 
A 1 393 ASN 393 377 377 ASN ASN A . n 
A 1 394 GLY 394 378 378 GLY GLY A . n 
A 1 395 ILE 395 379 379 ILE ILE A . n 
A 1 396 ILE 396 380 380 ILE ILE A . n 
A 1 397 TYR 397 381 381 TYR TYR A . n 
A 1 398 LEU 398 382 382 LEU LEU A . n 
A 1 399 LEU 399 383 383 LEU LEU A . n 
A 1 400 GLY 400 384 384 GLY GLY A . n 
A 1 401 GLY 401 385 385 GLY GLY A . n 
A 1 402 GLU 402 386 386 GLU GLU A . n 
A 1 403 GLU 403 387 387 GLU GLU A . n 
A 1 404 ASN 404 388 388 ASN ASN A . n 
A 1 405 ASP 405 389 389 ASP ASP A . n 
A 1 406 LEU 406 390 390 LEU LEU A . n 
A 1 407 ASP 407 391 391 ASP ASP A . n 
A 1 408 PHE 408 392 392 PHE PHE A . n 
A 1 409 PHE 409 393 393 PHE PHE A . n 
A 1 410 THR 410 394 394 THR THR A . n 
A 1 411 LYS 411 395 395 LYS LYS A . n 
A 1 412 PRO 412 396 396 PRO PRO A . n 
A 1 413 SER 413 397 397 SER SER A . n 
A 1 414 ARG 414 398 398 ARG ARG A . n 
A 1 415 LEU 415 399 399 LEU LEU A . n 
A 1 416 ILE 416 400 400 ILE ILE A . n 
A 1 417 GLN 417 401 401 GLN GLN A . n 
A 1 418 CYS 418 402 402 CYS CYS A . n 
A 1 419 PHE 419 403 403 PHE PHE A . n 
A 1 420 ASP 420 404 404 ASP ASP A . n 
A 1 421 THR 421 405 405 THR THR A . n 
A 1 422 GLU 422 406 406 GLU GLU A . n 
A 1 423 THR 423 407 407 THR THR A . n 
A 1 424 ASP 424 408 408 ASP ASP A . n 
A 1 425 LYS 425 409 409 LYS LYS A . n 
A 1 426 CYS 426 410 410 CYS CYS A . n 
A 1 427 HIS 427 411 411 HIS HIS A . n 
A 1 428 VAL 428 412 412 VAL VAL A . n 
A 1 429 LYS 429 413 413 LYS LYS A . n 
A 1 430 PRO 430 414 414 PRO PRO A . n 
A 1 431 TYR 431 415 415 TYR TYR A . n 
A 1 432 VAL 432 416 416 VAL VAL A . n 
A 1 433 LEU 433 417 417 LEU LEU A . n 
A 1 434 PRO 434 418 418 PRO PRO A . n 
A 1 435 PHE 435 419 419 PHE PHE A . n 
A 1 436 ALA 436 420 420 ALA ALA A . n 
A 1 437 GLY 437 421 421 GLY GLY A . n 
A 1 438 ARG 438 422 422 ARG ARG A . n 
A 1 439 MET 439 423 423 MET MET A . n 
A 1 440 HIS 440 424 424 HIS HIS A . n 
A 1 441 ALA 441 425 425 ALA ALA A . n 
A 1 442 ALA 442 426 426 ALA ALA A . n 
A 1 443 VAL 443 427 427 VAL VAL A . n 
A 1 444 HIS 444 428 428 HIS HIS A . n 
A 1 445 LYS 445 429 429 LYS LYS A . n 
A 1 446 ASP 446 430 430 ASP ASP A . n 
A 1 447 LEU 447 431 431 LEU LEU A . n 
A 1 448 VAL 448 432 432 VAL VAL A . n 
A 1 449 PHE 449 433 433 PHE PHE A . n 
A 1 450 ILE 450 434 434 ILE ILE A . n 
A 1 451 VAL 451 435 435 VAL VAL A . n 
A 1 452 ALA 452 436 436 ALA ALA A . n 
A 1 453 GLU 453 437 437 GLU GLU A . n 
A 1 454 GLY 454 438 438 GLY GLY A . n 
A 1 455 ASP 455 439 439 ASP ASP A . n 
A 1 456 SER 456 440 440 SER SER A . n 
A 1 457 LEU 457 441 441 LEU LEU A . n 
A 1 458 VAL 458 442 442 VAL VAL A . n 
A 1 459 CYS 459 443 443 CYS CYS A . n 
A 1 460 TYR 460 444 444 TYR TYR A . n 
A 1 461 ASN 461 445 445 ASN ASN A . n 
A 1 462 PRO 462 446 446 PRO PRO A . n 
A 1 463 LEU 463 447 447 LEU LEU A . n 
A 1 464 LEU 464 448 448 LEU LEU A . n 
A 1 465 ASP 465 449 449 ASP ASP A . n 
A 1 466 SER 466 450 450 SER SER A . n 
A 1 467 PHE 467 451 451 PHE PHE A . n 
A 1 468 THR 468 452 452 THR THR A . n 
A 1 469 ARG 469 453 453 ARG ARG A . n 
A 1 470 LEU 470 454 454 LEU LEU A . n 
A 1 471 CYS 471 455 455 CYS CYS A . n 
A 1 472 LEU 472 456 456 LEU LEU A . n 
A 1 473 PRO 473 457 457 PRO PRO A . n 
A 1 474 GLU 474 458 458 GLU GLU A . n 
A 1 475 ALA 475 459 459 ALA ALA A . n 
A 1 476 TRP 476 460 460 TRP TRP A . n 
A 1 477 SER 477 461 461 SER SER A . n 
A 1 478 SER 478 462 462 SER SER A . n 
A 1 479 ALA 479 463 463 ALA ALA A . n 
A 1 480 PRO 480 464 464 PRO PRO A . n 
A 1 481 SER 481 465 465 SER SER A . n 
A 1 482 LEU 482 466 466 LEU LEU A . n 
A 1 483 TRP 483 467 467 TRP TRP A . n 
A 1 484 LYS 484 468 468 LYS LYS A . n 
A 1 485 ILE 485 469 469 ILE ILE A . n 
A 1 486 ALA 486 470 470 ALA ALA A . n 
A 1 487 SER 487 471 471 SER SER A . n 
A 1 488 CYS 488 472 472 CYS CYS A . n 
A 1 489 ASN 489 473 473 ASN ASN A . n 
A 1 490 GLY 490 474 474 GLY GLY A . n 
A 1 491 SER 491 475 475 SER SER A . n 
A 1 492 ILE 492 476 476 ILE ILE A . n 
A 1 493 TYR 493 477 477 TYR TYR A . n 
A 1 494 VAL 494 478 478 VAL VAL A . n 
A 1 495 PHE 495 479 479 PHE PHE A . n 
A 1 496 ARG 496 480 480 ARG ARG A . n 
A 1 497 ASP 497 481 481 ASP ASP A . n 
A 1 498 ARG 498 482 482 ARG ARG A . n 
A 1 499 TYR 499 483 483 TYR TYR A . n 
A 1 500 LYS 500 484 484 LYS LYS A . n 
A 1 501 LYS 501 485 485 LYS LYS A . n 
A 1 502 GLY 502 486 486 GLY GLY A . n 
A 1 503 ASP 503 487 487 ASP ASP A . n 
A 1 504 ALA 504 488 488 ALA ALA A . n 
A 1 505 ASN 505 489 489 ASN ASN A . n 
A 1 506 THR 506 490 490 THR THR A . n 
A 1 507 TYR 507 491 491 TYR TYR A . n 
A 1 508 LYS 508 492 492 LYS LYS A . n 
A 1 509 LEU 509 493 493 LEU LEU A . n 
A 1 510 ASP 510 494 494 ASP ASP A . n 
A 1 511 PRO 511 495 495 PRO PRO A . n 
A 1 512 ALA 512 496 496 ALA ALA A . n 
A 1 513 THR 513 497 497 THR THR A . n 
A 1 514 SER 514 498 498 SER SER A . n 
A 1 515 ALA 515 499 499 ALA ALA A . n 
A 1 516 VAL 516 500 500 VAL VAL A . n 
A 1 517 THR 517 501 501 THR THR A . n 
A 1 518 VAL 518 502 502 VAL VAL A . n 
A 1 519 THR 519 503 503 THR THR A . n 
A 1 520 ARG 520 504 504 ARG ARG A . n 
A 1 521 GLY 521 505 505 GLY GLY A . n 
A 1 522 ILE 522 506 506 ILE ILE A . n 
A 1 523 LYS 523 507 507 LYS LYS A . n 
A 1 524 VAL 524 508 508 VAL VAL A . n 
A 1 525 LEU 525 509 509 LEU LEU A . n 
A 1 526 LEU 526 510 510 LEU LEU A . n 
A 1 527 THR 527 511 511 THR THR A . n 
A 1 528 ASN 528 512 512 ASN ASN A . n 
A 1 529 LEU 529 513 513 LEU LEU A . n 
A 1 530 GLN 530 514 514 GLN GLN A . n 
A 1 531 PHE 531 515 515 PHE PHE A . n 
A 1 532 VAL 532 516 516 VAL VAL A . n 
A 1 533 LEU 533 517 517 LEU LEU A . n 
A 1 534 ALA 534 518 518 ALA ALA A . n 
B 1 1   MET 1   -15 ?   ?   ?   B . n 
B 1 2   LYS 2   -14 ?   ?   ?   B . n 
B 1 3   GLY 3   -13 ?   ?   ?   B . n 
B 1 4   GLY 4   -12 ?   ?   ?   B . n 
B 1 5   ASN 5   -11 ?   ?   ?   B . n 
B 1 6   ALA 6   -10 ?   ?   ?   B . n 
B 1 7   ASP 7   -9  ?   ?   ?   B . n 
B 1 8   SER 8   -8  ?   ?   ?   B . n 
B 1 9   TRP 9   -7  ?   ?   ?   B . n 
B 1 10  GLN 10  -6  ?   ?   ?   B . n 
B 1 11  ARG 11  -5  ?   ?   ?   B . n 
B 1 12  GLU 12  -4  ?   ?   ?   B . n 
B 1 13  LYS 13  -3  ?   ?   ?   B . n 
B 1 14  LEU 14  -2  ?   ?   ?   B . n 
B 1 15  ALA 15  -1  ?   ?   ?   B . n 
B 1 16  SER 16  0   ?   ?   ?   B . n 
B 1 17  MET 17  1   ?   ?   ?   B . n 
B 1 18  GLU 18  2   ?   ?   ?   B . n 
B 1 19  SER 19  3   ?   ?   ?   B . n 
B 1 20  PRO 20  4   ?   ?   ?   B . n 
B 1 21  GLU 21  5   ?   ?   ?   B . n 
B 1 22  GLU 22  6   ?   ?   ?   B . n 
B 1 23  PRO 23  7   7   PRO PRO B . n 
B 1 24  GLY 24  8   8   GLY GLY B . n 
B 1 25  ALA 25  9   9   ALA ALA B . n 
B 1 26  SER 26  10  10  SER SER B . n 
B 1 27  MET 27  11  11  MET MET B . n 
B 1 28  ASP 28  12  12  ASP ASP B . n 
B 1 29  GLU 29  13  13  GLU GLU B . n 
B 1 30  ASN 30  14  14  ASN ASN B . n 
B 1 31  TYR 31  15  15  TYR TYR B . n 
B 1 32  PHE 32  16  16  PHE PHE B . n 
B 1 33  VAL 33  17  17  VAL VAL B . n 
B 1 34  ASN 34  18  18  ASN ASN B . n 
B 1 35  TYR 35  19  19  TYR TYR B . n 
B 1 36  THR 36  20  20  THR THR B . n 
B 1 37  PHE 37  21  21  PHE PHE B . n 
B 1 38  LYS 38  22  22  LYS LYS B . n 
B 1 39  ASP 39  23  23  ASP ASP B . n 
B 1 40  ARG 40  24  24  ARG ARG B . n 
B 1 41  SER 41  25  25  SER SER B . n 
B 1 42  HIS 42  26  26  HIS HIS B . n 
B 1 43  SER 43  27  27  SER SER B . n 
B 1 44  GLY 44  28  28  GLY GLY B . n 
B 1 45  ARG 45  29  29  ARG ARG B . n 
B 1 46  VAL 46  30  30  VAL VAL B . n 
B 1 47  ALA 47  31  31  ALA ALA B . n 
B 1 48  GLN 48  32  32  GLN GLN B . n 
B 1 49  GLY 49  33  33  GLY GLY B . n 
B 1 50  ILE 50  34  34  ILE ILE B . n 
B 1 51  MET 51  35  35  MET MET B . n 
B 1 52  LYS 52  36  36  LYS LYS B . n 
B 1 53  LEU 53  37  37  LEU LEU B . n 
B 1 54  CYS 54  38  38  CYS CYS B . n 
B 1 55  LEU 55  39  39  LEU LEU B . n 
B 1 56  GLU 56  40  40  GLU GLU B . n 
B 1 57  GLU 57  41  41  GLU GLU B . n 
B 1 58  GLU 58  42  42  GLU GLU B . n 
B 1 59  LEU 59  43  43  LEU LEU B . n 
B 1 60  PHE 60  44  44  PHE PHE B . n 
B 1 61  ALA 61  45  45  ALA ALA B . n 
B 1 62  ASP 62  46  46  ASP ASP B . n 
B 1 63  VAL 63  47  47  VAL VAL B . n 
B 1 64  THR 64  48  48  THR THR B . n 
B 1 65  ILE 65  49  49  ILE ILE B . n 
B 1 66  SER 66  50  50  SER SER B . n 
B 1 67  VAL 67  51  51  VAL VAL B . n 
B 1 68  GLU 68  52  52  GLU GLU B . n 
B 1 69  GLY 69  53  53  GLY GLY B . n 
B 1 70  ARG 70  54  54  ARG ARG B . n 
B 1 71  GLU 71  55  55  GLU GLU B . n 
B 1 72  PHE 72  56  56  PHE PHE B . n 
B 1 73  GLN 73  57  57  GLN GLN B . n 
B 1 74  LEU 74  58  58  LEU LEU B . n 
B 1 75  HIS 75  59  59  HIS HIS B . n 
B 1 76  ARG 76  60  60  ARG ARG B . n 
B 1 77  LEU 77  61  61  LEU LEU B . n 
B 1 78  VAL 78  62  62  VAL VAL B . n 
B 1 79  LEU 79  63  63  LEU LEU B . n 
B 1 80  SER 80  64  64  SER SER B . n 
B 1 81  ALA 81  65  65  ALA ALA B . n 
B 1 82  GLN 82  66  66  GLN GLN B . n 
B 1 83  SER 83  67  67  SER SER B . n 
B 1 84  CYS 84  68  68  CYS CYS B . n 
B 1 85  PHE 85  69  69  PHE PHE B . n 
B 1 86  PHE 86  70  70  PHE PHE B . n 
B 1 87  ARG 87  71  71  ARG ARG B . n 
B 1 88  SER 88  72  72  SER SER B . n 
B 1 89  MET 89  73  73  MET MET B . n 
B 1 90  PHE 90  74  74  PHE PHE B . n 
B 1 91  THR 91  75  75  THR THR B . n 
B 1 92  SER 92  76  76  SER SER B . n 
B 1 93  ASN 93  77  77  ASN ASN B . n 
B 1 94  LEU 94  78  78  LEU LEU B . n 
B 1 95  LYS 95  79  79  LYS LYS B . n 
B 1 96  GLU 96  80  80  GLU GLU B . n 
B 1 97  ALA 97  81  81  ALA ALA B . n 
B 1 98  HIS 98  82  82  HIS HIS B . n 
B 1 99  ASN 99  83  83  ASN ASN B . n 
B 1 100 ARG 100 84  84  ARG ARG B . n 
B 1 101 VAL 101 85  85  VAL VAL B . n 
B 1 102 ILE 102 86  86  ILE ILE B . n 
B 1 103 VAL 103 87  87  VAL VAL B . n 
B 1 104 LEU 104 88  88  LEU LEU B . n 
B 1 105 GLN 105 89  89  GLN GLN B . n 
B 1 106 ASP 106 90  90  ASP ASP B . n 
B 1 107 VAL 107 91  91  VAL VAL B . n 
B 1 108 SER 108 92  92  SER SER B . n 
B 1 109 GLU 109 93  93  GLU GLU B . n 
B 1 110 SER 110 94  94  SER SER B . n 
B 1 111 VAL 111 95  95  VAL VAL B . n 
B 1 112 PHE 112 96  96  PHE PHE B . n 
B 1 113 GLN 113 97  97  GLN GLN B . n 
B 1 114 LEU 114 98  98  LEU LEU B . n 
B 1 115 LEU 115 99  99  LEU LEU B . n 
B 1 116 VAL 116 100 100 VAL VAL B . n 
B 1 117 ASP 117 101 101 ASP ASP B . n 
B 1 118 TYR 118 102 102 TYR TYR B . n 
B 1 119 ILE 119 103 103 ILE ILE B . n 
B 1 120 TYR 120 104 104 TYR TYR B . n 
B 1 121 HIS 121 105 105 HIS HIS B . n 
B 1 122 GLY 122 106 106 GLY GLY B . n 
B 1 123 THR 123 107 107 THR THR B . n 
B 1 124 VAL 124 108 108 VAL VAL B . n 
B 1 125 LYS 125 109 109 LYS LYS B . n 
B 1 126 LEU 126 110 110 LEU LEU B . n 
B 1 127 ARG 127 111 111 ARG ARG B . n 
B 1 128 ALA 128 112 112 ALA ALA B . n 
B 1 129 GLU 129 113 113 GLU GLU B . n 
B 1 130 GLU 130 114 114 GLU GLU B . n 
B 1 131 LEU 131 115 115 LEU LEU B . n 
B 1 132 GLN 132 116 116 GLN GLN B . n 
B 1 133 GLU 133 117 117 GLU GLU B . n 
B 1 134 ILE 134 118 118 ILE ILE B . n 
B 1 135 TYR 135 119 119 TYR TYR B . n 
B 1 136 GLU 136 120 120 GLU GLU B . n 
B 1 137 VAL 137 121 121 VAL VAL B . n 
B 1 138 SER 138 122 122 SER SER B . n 
B 1 139 ASP 139 123 123 ASP ASP B . n 
B 1 140 MET 140 124 124 MET MET B . n 
B 1 141 TYR 141 125 125 TYR TYR B . n 
B 1 142 GLN 142 126 126 GLN GLN B . n 
B 1 143 LEU 143 127 127 LEU LEU B . n 
B 1 144 THR 144 128 128 THR THR B . n 
B 1 145 SER 145 129 129 SER SER B . n 
B 1 146 LEU 146 130 130 LEU LEU B . n 
B 1 147 PHE 147 131 131 PHE PHE B . n 
B 1 148 GLU 148 132 132 GLU GLU B . n 
B 1 149 GLU 149 133 133 GLU GLU B . n 
B 1 150 CYS 150 134 134 CYS CYS B . n 
B 1 151 SER 151 135 135 SER SER B . n 
B 1 152 ARG 152 136 136 ARG ARG B . n 
B 1 153 PHE 153 137 137 PHE PHE B . n 
B 1 154 LEU 154 138 138 LEU LEU B . n 
B 1 155 ALA 155 139 139 ALA ALA B . n 
B 1 156 ARG 156 140 140 ARG ARG B . n 
B 1 157 THR 157 141 141 THR THR B . n 
B 1 158 VAL 158 142 142 VAL VAL B . n 
B 1 159 GLN 159 143 143 GLN GLN B . n 
B 1 160 VAL 160 144 144 VAL VAL B . n 
B 1 161 GLY 161 145 145 GLY GLY B . n 
B 1 162 ASN 162 146 146 ASN ASN B . n 
B 1 163 CYS 163 147 147 CYS CYS B . n 
B 1 164 LEU 164 148 148 LEU LEU B . n 
B 1 165 GLN 165 149 149 GLN GLN B . n 
B 1 166 VAL 166 150 150 VAL VAL B . n 
B 1 167 MET 167 151 151 MET MET B . n 
B 1 168 TRP 168 152 152 TRP TRP B . n 
B 1 169 LEU 169 153 153 LEU LEU B . n 
B 1 170 ALA 170 154 154 ALA ALA B . n 
B 1 171 ASP 171 155 155 ASP ASP B . n 
B 1 172 ARG 172 156 156 ARG ARG B . n 
B 1 173 HIS 173 157 157 HIS HIS B . n 
B 1 174 SER 174 158 158 SER SER B . n 
B 1 175 ASP 175 159 159 ASP ASP B . n 
B 1 176 PRO 176 160 160 PRO PRO B . n 
B 1 177 GLU 177 161 161 GLU GLU B . n 
B 1 178 LEU 178 162 162 LEU LEU B . n 
B 1 179 TYR 179 163 163 TYR TYR B . n 
B 1 180 THR 180 164 164 THR THR B . n 
B 1 181 ALA 181 165 165 ALA ALA B . n 
B 1 182 ALA 182 166 166 ALA ALA B . n 
B 1 183 LYS 183 167 167 LYS LYS B . n 
B 1 184 HIS 184 168 168 HIS HIS B . n 
B 1 185 CYS 185 169 169 CYS CYS B . n 
B 1 186 ALA 186 170 170 ALA ALA B . n 
B 1 187 LYS 187 171 171 LYS LYS B . n 
B 1 188 THR 188 172 172 THR THR B . n 
B 1 189 HIS 189 173 173 HIS HIS B . n 
B 1 190 LEU 190 174 174 LEU LEU B . n 
B 1 191 ALA 191 175 175 ALA ALA B . n 
B 1 192 GLN 192 176 176 GLN GLN B . n 
B 1 193 LEU 193 177 177 LEU LEU B . n 
B 1 194 GLN 194 178 178 GLN GLN B . n 
B 1 195 ASN 195 179 179 ASN ASN B . n 
B 1 196 THR 196 180 180 THR THR B . n 
B 1 197 GLU 197 181 181 GLU GLU B . n 
B 1 198 GLU 198 182 182 GLU GLU B . n 
B 1 199 PHE 199 183 183 PHE PHE B . n 
B 1 200 LEU 200 184 184 LEU LEU B . n 
B 1 201 HIS 201 185 185 HIS HIS B . n 
B 1 202 LEU 202 186 186 LEU LEU B . n 
B 1 203 PRO 203 187 187 PRO PRO B . n 
B 1 204 HIS 204 188 188 HIS HIS B . n 
B 1 205 ARG 205 189 189 ARG ARG B . n 
B 1 206 LEU 206 190 190 LEU LEU B . n 
B 1 207 LEU 207 191 191 LEU LEU B . n 
B 1 208 THR 208 192 192 THR THR B . n 
B 1 209 ASP 209 193 193 ASP ASP B . n 
B 1 210 ILE 210 194 194 ILE ILE B . n 
B 1 211 ILE 211 195 195 ILE ILE B . n 
B 1 212 SER 212 196 196 SER SER B . n 
B 1 213 ASP 213 197 197 ASP ASP B . n 
B 1 214 GLY 214 198 198 GLY GLY B . n 
B 1 215 VAL 215 199 199 VAL VAL B . n 
B 1 216 PRO 216 200 200 PRO PRO B . n 
B 1 217 CYS 217 201 201 CYS CYS B . n 
B 1 218 SER 218 202 202 SER SER B . n 
B 1 219 GLN 219 203 203 GLN GLN B . n 
B 1 220 ASN 220 204 204 ASN ASN B . n 
B 1 221 PRO 221 205 205 PRO PRO B . n 
B 1 222 THR 222 206 206 THR THR B . n 
B 1 223 GLU 223 207 207 GLU GLU B . n 
B 1 224 ALA 224 208 208 ALA ALA B . n 
B 1 225 ILE 225 209 209 ILE ILE B . n 
B 1 226 GLU 226 210 210 GLU GLU B . n 
B 1 227 ALA 227 211 211 ALA ALA B . n 
B 1 228 TRP 228 212 212 TRP TRP B . n 
B 1 229 ILE 229 213 213 ILE ILE B . n 
B 1 230 ASN 230 214 214 ASN ASN B . n 
B 1 231 PHE 231 215 215 PHE PHE B . n 
B 1 232 ASN 232 216 216 ASN ASN B . n 
B 1 233 LYS 233 217 ?   ?   ?   B . n 
B 1 234 GLU 234 218 218 GLU GLU B . n 
B 1 235 GLU 235 219 219 GLU GLU B . n 
B 1 236 ARG 236 220 220 ARG ARG B . n 
B 1 237 GLU 237 221 221 GLU GLU B . n 
B 1 238 ALA 238 222 222 ALA ALA B . n 
B 1 239 PHE 239 223 223 PHE PHE B . n 
B 1 240 ALA 240 224 224 ALA ALA B . n 
B 1 241 GLU 241 225 225 GLU GLU B . n 
B 1 242 SER 242 226 226 SER SER B . n 
B 1 243 LEU 243 227 227 LEU LEU B . n 
B 1 244 ARG 244 228 228 ARG ARG B . n 
B 1 245 THR 245 229 229 THR THR B . n 
B 1 246 SER 246 230 230 SER SER B . n 
B 1 247 LEU 247 231 231 LEU LEU B . n 
B 1 248 LYS 248 232 232 LYS LYS B . n 
B 1 249 GLU 249 233 233 GLU GLU B . n 
B 1 250 ILE 250 234 234 ILE ILE B . n 
B 1 251 GLY 251 235 235 GLY GLY B . n 
B 1 252 GLU 252 236 236 GLU GLU B . n 
B 1 253 ASN 253 237 237 ASN ASN B . n 
B 1 254 VAL 254 238 238 VAL VAL B . n 
B 1 255 HIS 255 239 239 HIS HIS B . n 
B 1 256 ILE 256 240 240 ILE ILE B . n 
B 1 257 TYR 257 241 241 TYR TYR B . n 
B 1 258 LEU 258 242 242 LEU LEU B . n 
B 1 259 ILE 259 243 243 ILE ILE B . n 
B 1 260 GLY 260 244 244 GLY GLY B . n 
B 1 261 LYS 261 245 245 LYS LYS B . n 
B 1 262 GLU 262 246 246 GLU GLU B . n 
B 1 263 SER 263 247 247 SER SER B . n 
B 1 264 SER 264 248 248 SER SER B . n 
B 1 265 ARG 265 249 249 ARG ARG B . n 
B 1 266 THR 266 250 250 THR THR B . n 
B 1 267 HIS 267 251 251 HIS HIS B . n 
B 1 268 SER 268 252 252 SER SER B . n 
B 1 269 LEU 269 253 253 LEU LEU B . n 
B 1 270 ALA 270 254 254 ALA ALA B . n 
B 1 271 VAL 271 255 255 VAL VAL B . n 
B 1 272 SER 272 256 256 SER SER B . n 
B 1 273 LEU 273 257 257 LEU LEU B . n 
B 1 274 HIS 274 258 258 HIS HIS B . n 
B 1 275 CYS 275 259 259 CYS CYS B . n 
B 1 276 ALA 276 260 260 ALA ALA B . n 
B 1 277 GLU 277 261 261 GLU GLU B . n 
B 1 278 ASP 278 262 262 ASP ASP B . n 
B 1 279 ASP 279 263 263 ASP ASP B . n 
B 1 280 SER 280 264 264 SER SER B . n 
B 1 281 ILE 281 265 265 ILE ILE B . n 
B 1 282 SER 282 266 266 SER SER B . n 
B 1 283 VAL 283 267 267 VAL VAL B . n 
B 1 284 SER 284 268 268 SER SER B . n 
B 1 285 GLY 285 269 269 GLY GLY B . n 
B 1 286 GLN 286 270 270 GLN GLN B . n 
B 1 287 ASN 287 271 271 ASN ASN B . n 
B 1 288 SER 288 272 272 SER SER B . n 
B 1 289 LEU 289 273 273 LEU LEU B . n 
B 1 290 CYS 290 274 274 CYS CYS B . n 
B 1 291 HIS 291 275 275 HIS HIS B . n 
B 1 292 GLN 292 276 276 GLN GLN B . n 
B 1 293 ILE 293 277 277 ILE ILE B . n 
B 1 294 THR 294 278 278 THR THR B . n 
B 1 295 ALA 295 279 279 ALA ALA B . n 
B 1 296 ALA 296 280 280 ALA ALA B . n 
B 1 297 CYS 297 281 281 CYS CYS B . n 
B 1 298 LYS 298 282 282 LYS LYS B . n 
B 1 299 HIS 299 283 283 HIS HIS B . n 
B 1 300 GLY 300 284 284 GLY GLY B . n 
B 1 301 GLY 301 285 285 GLY GLY B . n 
B 1 302 ASP 302 286 286 ASP ASP B . n 
B 1 303 LEU 303 287 287 LEU LEU B . n 
B 1 304 TYR 304 288 288 TYR TYR B . n 
B 1 305 VAL 305 289 289 VAL VAL B . n 
B 1 306 VAL 306 290 290 VAL VAL B . n 
B 1 307 GLY 307 291 291 GLY GLY B . n 
B 1 308 GLY 308 292 292 GLY GLY B . n 
B 1 309 SER 309 293 293 SER SER B . n 
B 1 310 ILE 310 294 294 ILE ILE B . n 
B 1 311 PRO 311 295 295 PRO PRO B . n 
B 1 312 ARG 312 296 296 ARG ARG B . n 
B 1 313 ARG 313 297 297 ARG ARG B . n 
B 1 314 MET 314 298 298 MET MET B . n 
B 1 315 TRP 315 299 299 TRP TRP B . n 
B 1 316 LYS 316 300 300 LYS LYS B . n 
B 1 317 CYS 317 301 301 CYS CYS B . n 
B 1 318 ASN 318 302 302 ASN ASN B . n 
B 1 319 ASN 319 303 303 ASN ASN B . n 
B 1 320 ALA 320 304 304 ALA ALA B . n 
B 1 321 THR 321 305 305 THR THR B . n 
B 1 322 VAL 322 306 306 VAL VAL B . n 
B 1 323 ASP 323 307 307 ASP ASP B . n 
B 1 324 TRP 324 308 308 TRP TRP B . n 
B 1 325 GLU 325 309 309 GLU GLU B . n 
B 1 326 TRP 326 310 310 TRP TRP B . n 
B 1 327 CYS 327 311 311 CYS CYS B . n 
B 1 328 ALA 328 312 312 ALA ALA B . n 
B 1 329 PRO 329 313 313 PRO PRO B . n 
B 1 330 LEU 330 314 314 LEU LEU B . n 
B 1 331 PRO 331 315 315 PRO PRO B . n 
B 1 332 ARG 332 316 316 ARG ARG B . n 
B 1 333 ASP 333 317 317 ASP ASP B . n 
B 1 334 ARG 334 318 318 ARG ARG B . n 
B 1 335 LEU 335 319 319 LEU LEU B . n 
B 1 336 GLN 336 320 320 GLN GLN B . n 
B 1 337 HIS 337 321 321 HIS HIS B . n 
B 1 338 THR 338 322 322 THR THR B . n 
B 1 339 LEU 339 323 323 LEU LEU B . n 
B 1 340 VAL 340 324 324 VAL VAL B . n 
B 1 341 SER 341 325 325 SER SER B . n 
B 1 342 VAL 342 326 326 VAL VAL B . n 
B 1 343 PRO 343 327 327 PRO PRO B . n 
B 1 344 GLY 344 328 328 GLY GLY B . n 
B 1 345 LYS 345 329 329 LYS LYS B . n 
B 1 346 ASP 346 330 330 ASP ASP B . n 
B 1 347 ALA 347 331 331 ALA ALA B . n 
B 1 348 ILE 348 332 332 ILE ILE B . n 
B 1 349 TYR 349 333 333 TYR TYR B . n 
B 1 350 SER 350 334 334 SER SER B . n 
B 1 351 LEU 351 335 335 LEU LEU B . n 
B 1 352 GLY 352 336 336 GLY GLY B . n 
B 1 353 GLY 353 337 337 GLY GLY B . n 
B 1 354 LYS 354 338 338 LYS LYS B . n 
B 1 355 THR 355 339 339 THR THR B . n 
B 1 356 LEU 356 340 340 LEU LEU B . n 
B 1 357 GLN 357 341 341 GLN GLN B . n 
B 1 358 ASP 358 342 342 ASP ASP B . n 
B 1 359 THR 359 343 343 THR THR B . n 
B 1 360 LEU 360 344 344 LEU LEU B . n 
B 1 361 SER 361 345 345 SER SER B . n 
B 1 362 ASN 362 346 346 ASN ASN B . n 
B 1 363 ALA 363 347 347 ALA ALA B . n 
B 1 364 VAL 364 348 348 VAL VAL B . n 
B 1 365 ILE 365 349 349 ILE ILE B . n 
B 1 366 TYR 366 350 350 TYR TYR B . n 
B 1 367 TYR 367 351 351 TYR TYR B . n 
B 1 368 ARG 368 352 352 ARG ARG B . n 
B 1 369 VAL 369 353 353 VAL VAL B . n 
B 1 370 GLY 370 354 354 GLY GLY B . n 
B 1 371 ASP 371 355 355 ASP ASP B . n 
B 1 372 ASN 372 356 356 ASN ASN B . n 
B 1 373 VAL 373 357 357 VAL VAL B . n 
B 1 374 TRP 374 358 358 TRP TRP B . n 
B 1 375 THR 375 359 359 THR THR B . n 
B 1 376 GLU 376 360 360 GLU GLU B . n 
B 1 377 THR 377 361 361 THR THR B . n 
B 1 378 THR 378 362 362 THR THR B . n 
B 1 379 GLN 379 363 363 GLN GLN B . n 
B 1 380 LEU 380 364 364 LEU LEU B . n 
B 1 381 GLU 381 365 365 GLU GLU B . n 
B 1 382 VAL 382 366 366 VAL VAL B . n 
B 1 383 ALA 383 367 367 ALA ALA B . n 
B 1 384 VAL 384 368 368 VAL VAL B . n 
B 1 385 SER 385 369 369 SER SER B . n 
B 1 386 GLY 386 370 370 GLY GLY B . n 
B 1 387 ALA 387 371 371 ALA ALA B . n 
B 1 388 ALA 388 372 372 ALA ALA B . n 
B 1 389 GLY 389 373 373 GLY GLY B . n 
B 1 390 ALA 390 374 374 ALA ALA B . n 
B 1 391 ASN 391 375 375 ASN ASN B . n 
B 1 392 LEU 392 376 376 LEU LEU B . n 
B 1 393 ASN 393 377 377 ASN ASN B . n 
B 1 394 GLY 394 378 378 GLY GLY B . n 
B 1 395 ILE 395 379 379 ILE ILE B . n 
B 1 396 ILE 396 380 380 ILE ILE B . n 
B 1 397 TYR 397 381 381 TYR TYR B . n 
B 1 398 LEU 398 382 382 LEU LEU B . n 
B 1 399 LEU 399 383 383 LEU LEU B . n 
B 1 400 GLY 400 384 384 GLY GLY B . n 
B 1 401 GLY 401 385 385 GLY GLY B . n 
B 1 402 GLU 402 386 386 GLU GLU B . n 
B 1 403 GLU 403 387 387 GLU GLU B . n 
B 1 404 ASN 404 388 388 ASN ASN B . n 
B 1 405 ASP 405 389 389 ASP ASP B . n 
B 1 406 LEU 406 390 390 LEU LEU B . n 
B 1 407 ASP 407 391 391 ASP ASP B . n 
B 1 408 PHE 408 392 392 PHE PHE B . n 
B 1 409 PHE 409 393 393 PHE PHE B . n 
B 1 410 THR 410 394 394 THR THR B . n 
B 1 411 LYS 411 395 395 LYS LYS B . n 
B 1 412 PRO 412 396 396 PRO PRO B . n 
B 1 413 SER 413 397 397 SER SER B . n 
B 1 414 ARG 414 398 398 ARG ARG B . n 
B 1 415 LEU 415 399 399 LEU LEU B . n 
B 1 416 ILE 416 400 400 ILE ILE B . n 
B 1 417 GLN 417 401 401 GLN GLN B . n 
B 1 418 CYS 418 402 402 CYS CYS B . n 
B 1 419 PHE 419 403 403 PHE PHE B . n 
B 1 420 ASP 420 404 404 ASP ASP B . n 
B 1 421 THR 421 405 405 THR THR B . n 
B 1 422 GLU 422 406 406 GLU GLU B . n 
B 1 423 THR 423 407 407 THR THR B . n 
B 1 424 ASP 424 408 408 ASP ASP B . n 
B 1 425 LYS 425 409 409 LYS LYS B . n 
B 1 426 CYS 426 410 410 CYS CYS B . n 
B 1 427 HIS 427 411 411 HIS HIS B . n 
B 1 428 VAL 428 412 412 VAL VAL B . n 
B 1 429 LYS 429 413 413 LYS LYS B . n 
B 1 430 PRO 430 414 414 PRO PRO B . n 
B 1 431 TYR 431 415 415 TYR TYR B . n 
B 1 432 VAL 432 416 416 VAL VAL B . n 
B 1 433 LEU 433 417 417 LEU LEU B . n 
B 1 434 PRO 434 418 418 PRO PRO B . n 
B 1 435 PHE 435 419 419 PHE PHE B . n 
B 1 436 ALA 436 420 420 ALA ALA B . n 
B 1 437 GLY 437 421 421 GLY GLY B . n 
B 1 438 ARG 438 422 422 ARG ARG B . n 
B 1 439 MET 439 423 423 MET MET B . n 
B 1 440 HIS 440 424 424 HIS HIS B . n 
B 1 441 ALA 441 425 425 ALA ALA B . n 
B 1 442 ALA 442 426 426 ALA ALA B . n 
B 1 443 VAL 443 427 427 VAL VAL B . n 
B 1 444 HIS 444 428 428 HIS HIS B . n 
B 1 445 LYS 445 429 429 LYS LYS B . n 
B 1 446 ASP 446 430 430 ASP ASP B . n 
B 1 447 LEU 447 431 431 LEU LEU B . n 
B 1 448 VAL 448 432 432 VAL VAL B . n 
B 1 449 PHE 449 433 433 PHE PHE B . n 
B 1 450 ILE 450 434 434 ILE ILE B . n 
B 1 451 VAL 451 435 435 VAL VAL B . n 
B 1 452 ALA 452 436 436 ALA ALA B . n 
B 1 453 GLU 453 437 437 GLU GLU B . n 
B 1 454 GLY 454 438 438 GLY GLY B . n 
B 1 455 ASP 455 439 439 ASP ASP B . n 
B 1 456 SER 456 440 440 SER SER B . n 
B 1 457 LEU 457 441 441 LEU LEU B . n 
B 1 458 VAL 458 442 442 VAL VAL B . n 
B 1 459 CYS 459 443 443 CYS CYS B . n 
B 1 460 TYR 460 444 444 TYR TYR B . n 
B 1 461 ASN 461 445 445 ASN ASN B . n 
B 1 462 PRO 462 446 446 PRO PRO B . n 
B 1 463 LEU 463 447 447 LEU LEU B . n 
B 1 464 LEU 464 448 448 LEU LEU B . n 
B 1 465 ASP 465 449 449 ASP ASP B . n 
B 1 466 SER 466 450 450 SER SER B . n 
B 1 467 PHE 467 451 451 PHE PHE B . n 
B 1 468 THR 468 452 452 THR THR B . n 
B 1 469 ARG 469 453 453 ARG ARG B . n 
B 1 470 LEU 470 454 454 LEU LEU B . n 
B 1 471 CYS 471 455 455 CYS CYS B . n 
B 1 472 LEU 472 456 456 LEU LEU B . n 
B 1 473 PRO 473 457 457 PRO PRO B . n 
B 1 474 GLU 474 458 458 GLU GLU B . n 
B 1 475 ALA 475 459 459 ALA ALA B . n 
B 1 476 TRP 476 460 460 TRP TRP B . n 
B 1 477 SER 477 461 461 SER SER B . n 
B 1 478 SER 478 462 462 SER SER B . n 
B 1 479 ALA 479 463 463 ALA ALA B . n 
B 1 480 PRO 480 464 464 PRO PRO B . n 
B 1 481 SER 481 465 465 SER SER B . n 
B 1 482 LEU 482 466 466 LEU LEU B . n 
B 1 483 TRP 483 467 467 TRP TRP B . n 
B 1 484 LYS 484 468 468 LYS LYS B . n 
B 1 485 ILE 485 469 469 ILE ILE B . n 
B 1 486 ALA 486 470 470 ALA ALA B . n 
B 1 487 SER 487 471 471 SER SER B . n 
B 1 488 CYS 488 472 472 CYS CYS B . n 
B 1 489 ASN 489 473 473 ASN ASN B . n 
B 1 490 GLY 490 474 474 GLY GLY B . n 
B 1 491 SER 491 475 475 SER SER B . n 
B 1 492 ILE 492 476 476 ILE ILE B . n 
B 1 493 TYR 493 477 477 TYR TYR B . n 
B 1 494 VAL 494 478 478 VAL VAL B . n 
B 1 495 PHE 495 479 479 PHE PHE B . n 
B 1 496 ARG 496 480 480 ARG ARG B . n 
B 1 497 ASP 497 481 481 ASP ASP B . n 
B 1 498 ARG 498 482 482 ARG ARG B . n 
B 1 499 TYR 499 483 483 TYR TYR B . n 
B 1 500 LYS 500 484 484 LYS LYS B . n 
B 1 501 LYS 501 485 485 LYS LYS B . n 
B 1 502 GLY 502 486 486 GLY GLY B . n 
B 1 503 ASP 503 487 487 ASP ASP B . n 
B 1 504 ALA 504 488 488 ALA ALA B . n 
B 1 505 ASN 505 489 489 ASN ASN B . n 
B 1 506 THR 506 490 490 THR THR B . n 
B 1 507 TYR 507 491 491 TYR TYR B . n 
B 1 508 LYS 508 492 492 LYS LYS B . n 
B 1 509 LEU 509 493 493 LEU LEU B . n 
B 1 510 ASP 510 494 494 ASP ASP B . n 
B 1 511 PRO 511 495 495 PRO PRO B . n 
B 1 512 ALA 512 496 496 ALA ALA B . n 
B 1 513 THR 513 497 497 THR THR B . n 
B 1 514 SER 514 498 498 SER SER B . n 
B 1 515 ALA 515 499 499 ALA ALA B . n 
B 1 516 VAL 516 500 500 VAL VAL B . n 
B 1 517 THR 517 501 501 THR THR B . n 
B 1 518 VAL 518 502 502 VAL VAL B . n 
B 1 519 THR 519 503 503 THR THR B . n 
B 1 520 ARG 520 504 504 ARG ARG B . n 
B 1 521 GLY 521 505 505 GLY GLY B . n 
B 1 522 ILE 522 506 506 ILE ILE B . n 
B 1 523 LYS 523 507 507 LYS LYS B . n 
B 1 524 VAL 524 508 508 VAL VAL B . n 
B 1 525 LEU 525 509 509 LEU LEU B . n 
B 1 526 LEU 526 510 510 LEU LEU B . n 
B 1 527 THR 527 511 511 THR THR B . n 
B 1 528 ASN 528 512 512 ASN ASN B . n 
B 1 529 LEU 529 513 513 LEU LEU B . n 
B 1 530 GLN 530 514 514 GLN GLN B . n 
B 1 531 PHE 531 515 515 PHE PHE B . n 
B 1 532 VAL 532 516 516 VAL VAL B . n 
B 1 533 LEU 533 517 517 LEU LEU B . n 
B 1 534 ALA 534 518 518 ALA ALA B . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DTG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DTG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DTG 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9DTG 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 8244  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.608 ? 11192 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.935 ? 1106  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.042 ? 1267  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1438  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9DTG 
_struct.title                        'The cryo-EM structure of apo KBTBD4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DTG 
_struct_keywords.text            'molecular glue, targeted protein degradation, E3 ligase, transcription and tranlation, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    KBTB4_HUMAN 
_struct_ref.pdbx_db_accession          Q9NVX7 
_struct_ref.pdbx_db_isoform            Q9NVX7-2 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKGGNADSWQREKLASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLS
AQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQV
GNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFA
ESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNA
TVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLG
GEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAP
SLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9DTG A 1 ? 534 ? Q9NVX7 1 ? 534 ? -15 518 
2 1 9DTG B 1 ? 534 ? Q9NVX7 1 ? 534 ? -15 518 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 77  ? SER A 83  ? LEU A 61  SER A 67  1 ? 7  
HELX_P HELX_P2  AA2 SER A 83  ? SER A 92  ? SER A 67  SER A 76  1 ? 10 
HELX_P HELX_P3  AA3 LEU A 94  ? ASN A 99  ? LEU A 78  ASN A 83  5 ? 6  
HELX_P HELX_P4  AA4 SER A 108 ? HIS A 121 ? SER A 92  HIS A 105 1 ? 14 
HELX_P HELX_P5  AA5 ALA A 128 ? LEU A 131 ? ALA A 112 LEU A 115 5 ? 4  
HELX_P HELX_P6  AA6 GLN A 132 ? TYR A 141 ? GLN A 116 TYR A 125 1 ? 10 
HELX_P HELX_P7  AA7 LEU A 146 ? ALA A 155 ? LEU A 130 ALA A 139 1 ? 10 
HELX_P HELX_P8  AA8 GLN A 165 ? ASP A 171 ? GLN A 149 ASP A 155 1 ? 7  
HELX_P HELX_P9  AA9 ASP A 175 ? THR A 180 ? ASP A 159 THR A 164 1 ? 6  
HELX_P HELX_P10 AB1 HIS A 189 ? GLN A 194 ? HIS A 173 GLN A 178 1 ? 6  
HELX_P HELX_P11 AB2 THR A 196 ? HIS A 201 ? THR A 180 HIS A 185 1 ? 6  
HELX_P HELX_P12 AB3 PRO A 203 ? ILE A 211 ? PRO A 187 ILE A 195 1 ? 9  
HELX_P HELX_P13 AB4 SER A 212 ? GLY A 214 ? SER A 196 GLY A 198 5 ? 3  
HELX_P HELX_P14 AB5 ASN A 220 ? ILE A 229 ? ASN A 204 ILE A 213 1 ? 10 
HELX_P HELX_P15 AB6 GLU A 237 ? SER A 246 ? GLU A 221 SER A 230 1 ? 10 
HELX_P HELX_P16 AB7 PRO A 473 ? SER A 477 ? PRO A 457 SER A 461 5 ? 5  
HELX_P HELX_P17 AB8 ALA B 47  ? LEU B 55  ? ALA B 31  LEU B 39  1 ? 9  
HELX_P HELX_P18 AB9 HIS B 75  ? SER B 83  ? HIS B 59  SER B 67  1 ? 9  
HELX_P HELX_P19 AC1 PHE B 86  ? THR B 91  ? PHE B 70  THR B 75  1 ? 6  
HELX_P HELX_P20 AC2 SER B 108 ? TYR B 120 ? SER B 92  TYR B 104 1 ? 13 
HELX_P HELX_P21 AC3 GLN B 132 ? TYR B 141 ? GLN B 116 TYR B 125 1 ? 10 
HELX_P HELX_P22 AC4 SER B 145 ? GLU B 148 ? SER B 129 GLU B 132 5 ? 4  
HELX_P HELX_P23 AC5 GLU B 149 ? ALA B 155 ? GLU B 133 ALA B 139 1 ? 7  
HELX_P HELX_P24 AC6 GLN B 159 ? CYS B 163 ? GLN B 143 CYS B 147 5 ? 5  
HELX_P HELX_P25 AC7 LEU B 164 ? ASP B 171 ? LEU B 148 ASP B 155 1 ? 8  
HELX_P HELX_P26 AC8 ASP B 175 ? THR B 180 ? ASP B 159 THR B 164 1 ? 6  
HELX_P HELX_P27 AC9 LYS B 183 ? THR B 188 ? LYS B 167 THR B 172 1 ? 6  
HELX_P HELX_P28 AD1 HIS B 189 ? THR B 196 ? HIS B 173 THR B 180 1 ? 8  
HELX_P HELX_P29 AD2 THR B 196 ? HIS B 201 ? THR B 180 HIS B 185 1 ? 6  
HELX_P HELX_P30 AD3 PRO B 203 ? SER B 212 ? PRO B 187 SER B 196 1 ? 10 
HELX_P HELX_P31 AD4 ASN B 220 ? ASN B 230 ? ASN B 204 ASN B 214 1 ? 11 
HELX_P HELX_P32 AD5 GLU B 235 ? PHE B 239 ? GLU B 219 PHE B 223 5 ? 5  
HELX_P HELX_P33 AD6 VAL B 342 ? ASP B 346 ? VAL B 326 ASP B 330 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            163 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           A 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            185 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             147 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             169 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.032 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       163 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      185 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        147 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       169 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          ILE 
_struct_mon_prot_cis.label_seq_id           310 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           ILE 
_struct_mon_prot_cis.auth_seq_id            294 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    311 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     295 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -0.57 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 3 ? 
AA7 ? 3 ? 
AA8 ? 3 ? 
AA9 ? 2 ? 
AB1 ? 3 ? 
AB2 ? 2 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 4 ? 
AB6 ? 3 ? 
AB7 ? 2 ? 
AB8 ? 4 ? 
AB9 ? 3 ? 
AC1 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA3 1 2 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? parallel      
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AC1 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 37  ? LYS A 38  ? PHE A 21  LYS A 22  
AA1 2 THR B 123 ? VAL B 124 ? THR B 107 VAL B 108 
AA2 1 THR A 64  ? VAL A 67  ? THR A 48  VAL A 51  
AA2 2 VAL A 101 ? LEU A 104 ? VAL A 85  LEU A 88  
AA3 1 VAL A 215 ? PRO A 216 ? VAL A 199 PRO A 200 
AA3 2 GLU A 249 ? ILE A 250 ? GLU A 233 ILE A 234 
AA4 1 ILE A 281 ? ASN A 287 ? ILE A 265 ASN A 271 
AA4 2 LEU A 269 ? CYS A 275 ? LEU A 253 CYS A 259 
AA4 3 ILE A 259 ? GLY A 260 ? ILE A 243 GLY A 244 
AA4 4 PHE A 531 ? VAL A 532 ? PHE A 515 VAL A 516 
AA5 1 ILE A 293 ? ALA A 295 ? ILE A 277 ALA A 279 
AA5 2 ASP A 302 ? GLY A 307 ? ASP A 286 GLY A 291 
AA5 3 LYS A 298 ? HIS A 299 ? LYS A 282 HIS A 283 
AA6 1 ILE A 293 ? ALA A 295 ? ILE A 277 ALA A 279 
AA6 2 ASP A 302 ? GLY A 307 ? ASP A 286 GLY A 291 
AA6 3 ARG A 313 ? LYS A 316 ? ARG A 297 LYS A 300 
AA7 1 VAL A 340 ? VAL A 342 ? VAL A 324 VAL A 326 
AA7 2 ALA A 347 ? TYR A 349 ? ALA A 331 TYR A 333 
AA7 3 TYR A 366 ? ARG A 368 ? TYR A 350 ARG A 352 
AA8 1 ALA A 388 ? ALA A 390 ? ALA A 372 ALA A 374 
AA8 2 TYR A 397 ? LEU A 399 ? TYR A 381 LEU A 383 
AA8 3 ILE A 416 ? GLN A 417 ? ILE A 400 GLN A 401 
AA9 1 GLU A 402 ? ASN A 404 ? GLU A 386 ASN A 388 
AA9 2 THR A 410 ? PRO A 412 ? THR A 394 PRO A 396 
AB1 1 HIS A 440 ? HIS A 444 ? HIS A 424 HIS A 428 
AB1 2 LEU A 447 ? VAL A 451 ? LEU A 431 VAL A 435 
AB1 3 VAL A 458 ? TYR A 460 ? VAL A 442 TYR A 444 
AB2 1 ILE A 485 ? CYS A 488 ? ILE A 469 CYS A 472 
AB2 2 SER A 491 ? VAL A 494 ? SER A 475 VAL A 478 
AB3 1 VAL B 63  ? ILE B 65  ? VAL B 47  ILE B 49  
AB3 2 PHE B 72  ? LEU B 74  ? PHE B 56  LEU B 58  
AB4 1 VAL B 215 ? PRO B 216 ? VAL B 199 PRO B 200 
AB4 2 GLU B 249 ? ILE B 250 ? GLU B 233 ILE B 234 
AB5 1 GLN B 286 ? SER B 288 ? GLN B 270 SER B 272 
AB5 2 SER B 268 ? LEU B 273 ? SER B 252 LEU B 257 
AB5 3 ILE B 256 ? LYS B 261 ? ILE B 240 LYS B 245 
AB5 4 PHE B 531 ? LEU B 533 ? PHE B 515 LEU B 517 
AB6 1 ILE B 293 ? HIS B 299 ? ILE B 277 HIS B 283 
AB6 2 ASP B 302 ? GLY B 307 ? ASP B 286 GLY B 291 
AB6 3 ARG B 313 ? LYS B 316 ? ARG B 297 LYS B 300 
AB7 1 THR B 338 ? LEU B 339 ? THR B 322 LEU B 323 
AB7 2 SER B 350 ? LEU B 351 ? SER B 334 LEU B 335 
AB8 1 ALA B 388 ? LEU B 392 ? ALA B 372 LEU B 376 
AB8 2 ILE B 395 ? LEU B 399 ? ILE B 379 LEU B 383 
AB8 3 GLN B 417 ? PHE B 419 ? GLN B 401 PHE B 403 
AB8 4 HIS B 427 ? VAL B 428 ? HIS B 411 VAL B 412 
AB9 1 HIS B 440 ? HIS B 444 ? HIS B 424 HIS B 428 
AB9 2 LEU B 447 ? VAL B 451 ? LEU B 431 VAL B 435 
AB9 3 VAL B 458 ? TYR B 460 ? VAL B 442 TYR B 444 
AC1 1 TRP B 483 ? CYS B 488 ? TRP B 467 CYS B 472 
AC1 2 SER B 491 ? ARG B 496 ? SER B 475 ARG B 480 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 37  ? N PHE A 21  O VAL B 124 ? O VAL B 108 
AA2 1 2 N SER A 66  ? N SER A 50  O ILE A 102 ? O ILE A 86  
AA3 1 2 N VAL A 215 ? N VAL A 199 O ILE A 250 ? O ILE A 234 
AA4 1 2 O SER A 282 ? O SER A 266 N HIS A 274 ? N HIS A 258 
AA4 2 3 O LEU A 269 ? O LEU A 253 N GLY A 260 ? N GLY A 244 
AA4 3 4 N ILE A 259 ? N ILE A 243 O VAL A 532 ? O VAL A 516 
AA5 1 2 N THR A 294 ? N THR A 278 O VAL A 306 ? O VAL A 290 
AA5 2 3 O ASP A 302 ? O ASP A 286 N HIS A 299 ? N HIS A 283 
AA6 1 2 N THR A 294 ? N THR A 278 O VAL A 306 ? O VAL A 290 
AA6 2 3 N VAL A 305 ? N VAL A 289 O TRP A 315 ? O TRP A 299 
AA7 1 2 N VAL A 342 ? N VAL A 326 O ALA A 347 ? O ALA A 331 
AA7 2 3 N ILE A 348 ? N ILE A 332 O TYR A 367 ? O TYR A 351 
AA8 1 2 N ALA A 390 ? N ALA A 374 O TYR A 397 ? O TYR A 381 
AA8 2 3 N LEU A 398 ? N LEU A 382 O GLN A 417 ? O GLN A 401 
AA9 1 2 N GLU A 403 ? N GLU A 387 O LYS A 411 ? O LYS A 395 
AB1 1 2 N HIS A 444 ? N HIS A 428 O LEU A 447 ? O LEU A 431 
AB1 2 3 N VAL A 448 ? N VAL A 432 O TYR A 460 ? O TYR A 444 
AB2 1 2 N ALA A 486 ? N ALA A 470 O TYR A 493 ? O TYR A 477 
AB3 1 2 N ILE B 65  ? N ILE B 49  O PHE B 72  ? O PHE B 56  
AB4 1 2 N VAL B 215 ? N VAL B 199 O ILE B 250 ? O ILE B 234 
AB5 1 2 O ASN B 287 ? O ASN B 271 N ALA B 270 ? N ALA B 254 
AB5 2 3 O LEU B 269 ? O LEU B 253 N GLY B 260 ? N GLY B 244 
AB5 3 4 N TYR B 257 ? N TYR B 241 O LEU B 533 ? O LEU B 517 
AB6 1 2 N ALA B 295 ? N ALA B 279 O VAL B 306 ? O VAL B 290 
AB6 2 3 N VAL B 305 ? N VAL B 289 O TRP B 315 ? O TRP B 299 
AB7 1 2 N THR B 338 ? N THR B 322 O LEU B 351 ? O LEU B 335 
AB8 1 2 N LEU B 392 ? N LEU B 376 O ILE B 395 ? O ILE B 379 
AB8 2 3 N LEU B 398 ? N LEU B 382 O GLN B 417 ? O GLN B 401 
AB8 3 4 N CYS B 418 ? N CYS B 402 O HIS B 427 ? O HIS B 411 
AB9 1 2 N HIS B 444 ? N HIS B 428 O LEU B 447 ? O LEU B 431 
AB9 2 3 N ILE B 450 ? N ILE B 434 O VAL B 458 ? O VAL B 442 
AC1 1 2 N ALA B 486 ? N ALA B 470 O TYR B 493 ? O TYR B 477 
# 
_pdbx_entry_details.entry_id                   9DTG 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 10  ? ? 107.41  113.84  
2  1 GLU A 52  ? ? 53.40   -131.70 
3  1 ARG A 111 ? ? -79.06  -166.70 
4  1 GLU A 114 ? ? -93.51  50.96   
5  1 CYS A 147 ? ? -85.54  48.39   
6  1 HIS A 168 ? ? -84.80  46.87   
7  1 CYS A 169 ? ? -131.15 -37.52  
8  1 ASP A 262 ? ? -99.77  33.46   
9  1 SER A 268 ? ? -140.57 43.08   
10 1 LYS A 329 ? ? -161.62 101.81  
11 1 ASP A 330 ? ? -57.58  49.53   
12 1 ASN A 377 ? ? 59.37   -128.07 
13 1 LEU A 390 ? ? -130.96 -40.62  
14 1 ASP A 391 ? ? -95.32  48.19   
15 1 PHE A 392 ? ? 57.51   5.75    
16 1 PRO A 414 ? ? -83.63  45.97   
17 1 LYS A 429 ? ? 52.33   -128.80 
18 1 SER A 440 ? ? -141.52 46.31   
19 1 TRP A 460 ? ? -95.80  58.47   
20 1 SER A 475 ? ? -161.83 114.72  
21 1 ASP A 481 ? ? -79.06  -165.47 
22 1 ASP B 12  ? ? -142.03 18.33   
23 1 ASN B 18  ? ? 173.87  159.90  
24 1 THR B 20  ? ? -142.21 29.62   
25 1 PHE B 21  ? ? -36.63  116.39  
26 1 HIS B 26  ? ? -90.70  52.67   
27 1 TYR B 104 ? ? -79.98  -155.30 
28 1 HIS B 105 ? ? -29.55  -47.71  
29 1 PHE B 131 ? ? -87.45  44.77   
30 1 ASP B 155 ? ? -89.15  48.83   
31 1 HIS B 173 ? ? -92.03  51.28   
32 1 ASP B 330 ? ? 33.13   63.57   
33 1 TYR B 333 ? ? -35.02  124.44  
34 1 ASN B 377 ? ? 45.84   29.97   
35 1 PRO B 414 ? ? -78.20  47.44   
36 1 LYS B 429 ? ? 54.06   -108.91 
37 1 THR B 511 ? ? -91.71  50.04   
38 1 ASN B 512 ? ? -171.40 143.76  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9DTG 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9DTG 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.83 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               550442 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'KBTBD4 dimer' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9DTG 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9DTG 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9DTG 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -15 ? A MET 1   
2  1 Y 1 A LYS -14 ? A LYS 2   
3  1 Y 1 A GLY -13 ? A GLY 3   
4  1 Y 1 A GLY -12 ? A GLY 4   
5  1 Y 1 A ASN -11 ? A ASN 5   
6  1 Y 1 A ALA -10 ? A ALA 6   
7  1 Y 1 A ASP -9  ? A ASP 7   
8  1 Y 1 A SER -8  ? A SER 8   
9  1 Y 1 A TRP -7  ? A TRP 9   
10 1 Y 1 A GLN -6  ? A GLN 10  
11 1 Y 1 A ARG -5  ? A ARG 11  
12 1 Y 1 A GLU -4  ? A GLU 12  
13 1 Y 1 A LYS -3  ? A LYS 13  
14 1 Y 1 A LEU -2  ? A LEU 14  
15 1 Y 1 A ALA -1  ? A ALA 15  
16 1 Y 1 A SER 0   ? A SER 16  
17 1 Y 1 A MET 1   ? A MET 17  
18 1 Y 1 A GLU 2   ? A GLU 18  
19 1 Y 1 A SER 3   ? A SER 19  
20 1 Y 1 A PRO 4   ? A PRO 20  
21 1 Y 1 A GLU 5   ? A GLU 21  
22 1 Y 1 A GLU 6   ? A GLU 22  
23 1 Y 1 B MET -15 ? B MET 1   
24 1 Y 1 B LYS -14 ? B LYS 2   
25 1 Y 1 B GLY -13 ? B GLY 3   
26 1 Y 1 B GLY -12 ? B GLY 4   
27 1 Y 1 B ASN -11 ? B ASN 5   
28 1 Y 1 B ALA -10 ? B ALA 6   
29 1 Y 1 B ASP -9  ? B ASP 7   
30 1 Y 1 B SER -8  ? B SER 8   
31 1 Y 1 B TRP -7  ? B TRP 9   
32 1 Y 1 B GLN -6  ? B GLN 10  
33 1 Y 1 B ARG -5  ? B ARG 11  
34 1 Y 1 B GLU -4  ? B GLU 12  
35 1 Y 1 B LYS -3  ? B LYS 13  
36 1 Y 1 B LEU -2  ? B LEU 14  
37 1 Y 1 B ALA -1  ? B ALA 15  
38 1 Y 1 B SER 0   ? B SER 16  
39 1 Y 1 B MET 1   ? B MET 17  
40 1 Y 1 B GLU 2   ? B GLU 18  
41 1 Y 1 B SER 3   ? B SER 19  
42 1 Y 1 B PRO 4   ? B PRO 20  
43 1 Y 1 B GLU 5   ? B GLU 21  
44 1 Y 1 B GLU 6   ? B GLU 22  
45 1 Y 1 B LYS 217 ? B LYS 233 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-30 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9DTG 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'The cryo-EM structure of apo KBTBD4' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7111 
_em_entity_assembly_recombinant.organism             'Trichoplusia ni' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Howard Hughes Medical Institute (HHMI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9DTG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . PRO A 1 23  ? 156.009 167.644 191.593 1.00 18.39 ? 7   PRO A N   1 
ATOM 2    C CA  . PRO A 1 23  ? 155.337 166.970 192.707 1.00 18.39 ? 7   PRO A CA  1 
ATOM 3    C C   . PRO A 1 23  ? 154.611 167.955 193.616 1.00 18.39 ? 7   PRO A C   1 
ATOM 4    O O   . PRO A 1 23  ? 155.141 169.027 193.896 1.00 18.39 ? 7   PRO A O   1 
ATOM 5    C CB  . PRO A 1 23  ? 156.489 166.290 193.444 1.00 18.39 ? 7   PRO A CB  1 
ATOM 6    C CG  . PRO A 1 23  ? 157.509 166.018 192.377 1.00 18.39 ? 7   PRO A CG  1 
ATOM 7    C CD  . PRO A 1 23  ? 157.280 166.988 191.240 1.00 18.39 ? 7   PRO A CD  1 
ATOM 8    N N   . GLY A 1 24  ? 153.403 167.606 194.052 1.00 17.64 ? 8   GLY A N   1 
ATOM 9    C CA  . GLY A 1 24  ? 152.645 168.490 194.914 1.00 17.64 ? 8   GLY A CA  1 
ATOM 10   C C   . GLY A 1 24  ? 152.272 167.912 196.264 1.00 17.64 ? 8   GLY A C   1 
ATOM 11   O O   . GLY A 1 24  ? 152.162 168.649 197.248 1.00 17.64 ? 8   GLY A O   1 
ATOM 12   N N   . ALA A 1 25  ? 152.082 166.595 196.331 1.00 18.59 ? 9   ALA A N   1 
ATOM 13   C CA  . ALA A 1 25  ? 151.475 165.989 197.510 1.00 18.59 ? 9   ALA A CA  1 
ATOM 14   C C   . ALA A 1 25  ? 151.988 164.579 197.774 1.00 18.59 ? 9   ALA A C   1 
ATOM 15   O O   . ALA A 1 25  ? 153.068 164.211 197.298 1.00 18.59 ? 9   ALA A O   1 
ATOM 16   C CB  . ALA A 1 25  ? 149.951 165.968 197.367 1.00 18.59 ? 9   ALA A CB  1 
ATOM 17   N N   . SER A 1 26  ? 151.215 163.830 198.575 1.00 15.26 ? 10  SER A N   1 
ATOM 18   C CA  . SER A 1 26  ? 151.379 162.437 199.000 1.00 15.26 ? 10  SER A CA  1 
ATOM 19   C C   . SER A 1 26  ? 151.797 162.390 200.465 1.00 15.26 ? 10  SER A C   1 
ATOM 20   O O   . SER A 1 26  ? 152.895 162.826 200.822 1.00 15.26 ? 10  SER A O   1 
ATOM 21   C CB  . SER A 1 26  ? 152.377 161.653 198.141 1.00 15.26 ? 10  SER A CB  1 
ATOM 22   O OG  . SER A 1 26  ? 151.750 161.140 196.978 1.00 15.26 ? 10  SER A OG  1 
ATOM 23   N N   . MET A 1 27  ? 150.919 161.857 201.315 1.00 16.56 ? 11  MET A N   1 
ATOM 24   C CA  . MET A 1 27  ? 151.152 161.826 202.753 1.00 16.56 ? 11  MET A CA  1 
ATOM 25   C C   . MET A 1 27  ? 151.912 160.544 203.072 1.00 16.56 ? 11  MET A C   1 
ATOM 26   O O   . MET A 1 27  ? 152.614 160.453 204.083 1.00 16.56 ? 11  MET A O   1 
ATOM 27   C CB  . MET A 1 27  ? 149.809 161.897 203.495 1.00 16.56 ? 11  MET A CB  1 
ATOM 28   C CG  . MET A 1 27  ? 149.804 161.654 205.011 1.00 16.56 ? 11  MET A CG  1 
ATOM 29   S SD  . MET A 1 27  ? 151.258 162.198 205.936 1.00 16.56 ? 11  MET A SD  1 
ATOM 30   C CE  . MET A 1 27  ? 151.287 161.002 207.269 1.00 16.56 ? 11  MET A CE  1 
ATOM 31   N N   . ASP A 1 28  ? 151.827 159.558 202.179 1.00 13.83 ? 12  ASP A N   1 
ATOM 32   C CA  . ASP A 1 28  ? 152.517 158.294 202.375 1.00 13.83 ? 12  ASP A CA  1 
ATOM 33   C C   . ASP A 1 28  ? 154.009 158.368 202.102 1.00 13.83 ? 12  ASP A C   1 
ATOM 34   O O   . ASP A 1 28  ? 154.768 157.624 202.732 1.00 13.83 ? 12  ASP A O   1 
ATOM 35   C CB  . ASP A 1 28  ? 151.911 157.199 201.483 1.00 13.83 ? 12  ASP A CB  1 
ATOM 36   C CG  . ASP A 1 28  ? 152.341 155.809 201.899 1.00 13.83 ? 12  ASP A CG  1 
ATOM 37   O OD1 . ASP A 1 28  ? 151.936 155.367 202.994 1.00 13.83 ? 12  ASP A OD1 1 
ATOM 38   O OD2 . ASP A 1 28  ? 153.087 155.160 201.135 1.00 13.83 ? 12  ASP A OD2 1 
ATOM 39   N N   . GLU A 1 29  ? 154.450 159.236 201.197 1.00 8.36  ? 13  GLU A N   1 
ATOM 40   C CA  . GLU A 1 29  ? 155.875 159.431 200.961 1.00 8.36  ? 13  GLU A CA  1 
ATOM 41   C C   . GLU A 1 29  ? 156.453 160.267 202.093 1.00 8.36  ? 13  GLU A C   1 
ATOM 42   O O   . GLU A 1 29  ? 156.490 161.497 202.007 1.00 8.36  ? 13  GLU A O   1 
ATOM 43   C CB  . GLU A 1 29  ? 156.098 160.106 199.611 1.00 8.36  ? 13  GLU A CB  1 
ATOM 44   C CG  . GLU A 1 29  ? 156.244 159.149 198.435 1.00 8.36  ? 13  GLU A CG  1 
ATOM 45   C CD  . GLU A 1 29  ? 154.951 158.436 198.071 1.00 8.36  ? 13  GLU A CD  1 
ATOM 46   O OE1 . GLU A 1 29  ? 154.978 157.610 197.135 1.00 8.36  ? 13  GLU A OE1 1 
ATOM 47   O OE2 . GLU A 1 29  ? 153.907 158.707 198.700 1.00 8.36  ? 13  GLU A OE2 1 
ATOM 48   N N   . ASN A 1 30  ? 156.918 159.600 203.156 1.00 3.40  ? 14  ASN A N   1 
ATOM 49   C CA  . ASN A 1 30  ? 157.504 160.262 204.316 1.00 3.40  ? 14  ASN A CA  1 
ATOM 50   C C   . ASN A 1 30  ? 158.992 159.907 204.339 1.00 3.40  ? 14  ASN A C   1 
ATOM 51   O O   . ASN A 1 30  ? 159.386 158.759 204.532 1.00 3.40  ? 14  ASN A O   1 
ATOM 52   C CB  . ASN A 1 30  ? 156.801 159.859 205.613 1.00 3.40  ? 14  ASN A CB  1 
ATOM 53   C CG  . ASN A 1 30  ? 157.342 160.597 206.819 1.00 3.40  ? 14  ASN A CG  1 
ATOM 54   O OD1 . ASN A 1 30  ? 157.966 161.649 206.689 1.00 3.40  ? 14  ASN A OD1 1 
ATOM 55   N ND2 . ASN A 1 30  ? 157.102 160.048 208.004 1.00 3.40  ? 14  ASN A ND2 1 
ATOM 56   N N   . TYR A 1 31  ? 159.828 160.924 204.138 1.00 2.68  ? 15  TYR A N   1 
ATOM 57   C CA  . TYR A 1 31  ? 161.250 160.747 203.866 1.00 2.68  ? 15  TYR A CA  1 
ATOM 58   C C   . TYR A 1 31  ? 161.985 159.998 204.971 1.00 2.68  ? 15  TYR A C   1 
ATOM 59   O O   . TYR A 1 31  ? 162.962 159.293 204.700 1.00 2.68  ? 15  TYR A O   1 
ATOM 60   C CB  . TYR A 1 31  ? 161.906 162.109 203.628 1.00 2.68  ? 15  TYR A CB  1 
ATOM 61   C CG  . TYR A 1 31  ? 161.635 162.683 202.255 1.00 2.68  ? 15  TYR A CG  1 
ATOM 62   C CD1 . TYR A 1 31  ? 160.359 162.668 201.711 1.00 2.68  ? 15  TYR A CD1 1 
ATOM 63   C CD2 . TYR A 1 31  ? 162.657 163.232 201.500 1.00 2.68  ? 15  TYR A CD2 1 
ATOM 64   C CE1 . TYR A 1 31  ? 160.113 163.183 200.460 1.00 2.68  ? 15  TYR A CE1 1 
ATOM 65   C CE2 . TYR A 1 31  ? 162.417 163.748 200.248 1.00 2.68  ? 15  TYR A CE2 1 
ATOM 66   C CZ  . TYR A 1 31  ? 161.143 163.723 199.733 1.00 2.68  ? 15  TYR A CZ  1 
ATOM 67   O OH  . TYR A 1 31  ? 160.897 164.239 198.484 1.00 2.68  ? 15  TYR A OH  1 
ATOM 68   N N   . PHE A 1 32  ? 161.535 160.138 206.213 1.00 2.62  ? 16  PHE A N   1 
ATOM 69   C CA  . PHE A 1 32  ? 162.196 159.506 207.346 1.00 2.62  ? 16  PHE A CA  1 
ATOM 70   C C   . PHE A 1 32  ? 161.797 158.048 207.543 1.00 2.62  ? 16  PHE A C   1 
ATOM 71   O O   . PHE A 1 32  ? 162.461 157.340 208.306 1.00 2.62  ? 16  PHE A O   1 
ATOM 72   C CB  . PHE A 1 32  ? 161.922 160.304 208.621 1.00 2.62  ? 16  PHE A CB  1 
ATOM 73   C CG  . PHE A 1 32  ? 162.496 161.690 208.596 1.00 2.62  ? 16  PHE A CG  1 
ATOM 74   C CD1 . PHE A 1 32  ? 163.847 161.884 208.379 1.00 2.62  ? 16  PHE A CD1 1 
ATOM 75   C CD2 . PHE A 1 32  ? 161.687 162.797 208.760 1.00 2.62  ? 16  PHE A CD2 1 
ATOM 76   C CE1 . PHE A 1 32  ? 164.382 163.153 208.349 1.00 2.62  ? 16  PHE A CE1 1 
ATOM 77   C CE2 . PHE A 1 32  ? 162.219 164.068 208.721 1.00 2.62  ? 16  PHE A CE2 1 
ATOM 78   C CZ  . PHE A 1 32  ? 163.568 164.245 208.520 1.00 2.62  ? 16  PHE A CZ  1 
ATOM 79   N N   . VAL A 1 33  ? 160.737 157.580 206.886 1.00 1.65  ? 17  VAL A N   1 
ATOM 80   C CA  . VAL A 1 33  ? 160.340 156.182 207.017 1.00 1.65  ? 17  VAL A CA  1 
ATOM 81   C C   . VAL A 1 33  ? 160.205 155.516 205.650 1.00 1.65  ? 17  VAL A C   1 
ATOM 82   O O   . VAL A 1 33  ? 160.756 154.433 205.427 1.00 1.65  ? 17  VAL A O   1 
ATOM 83   C CB  . VAL A 1 33  ? 159.049 156.040 207.850 1.00 1.65  ? 17  VAL A CB  1 
ATOM 84   C CG1 . VAL A 1 33  ? 157.910 156.863 207.269 1.00 1.65  ? 17  VAL A CG1 1 
ATOM 85   C CG2 . VAL A 1 33  ? 158.652 154.576 207.961 1.00 1.65  ? 17  VAL A CG2 1 
ATOM 86   N N   . ASN A 1 34  ? 159.476 156.145 204.727 1.00 2.07  ? 18  ASN A N   1 
ATOM 87   C CA  . ASN A 1 34  ? 159.193 155.506 203.447 1.00 2.07  ? 18  ASN A CA  1 
ATOM 88   C C   . ASN A 1 34  ? 158.899 156.539 202.364 1.00 2.07  ? 18  ASN A C   1 
ATOM 89   O O   . ASN A 1 34  ? 157.800 157.099 202.322 1.00 2.07  ? 18  ASN A O   1 
ATOM 90   C CB  . ASN A 1 34  ? 158.013 154.539 203.605 1.00 2.07  ? 18  ASN A CB  1 
ATOM 91   C CG  . ASN A 1 34  ? 157.485 154.007 202.277 1.00 2.07  ? 18  ASN A CG  1 
ATOM 92   O OD1 . ASN A 1 34  ? 158.114 154.150 201.228 1.00 2.07  ? 18  ASN A OD1 1 
ATOM 93   N ND2 . ASN A 1 34  ? 156.311 153.389 202.325 1.00 2.07  ? 18  ASN A ND2 1 
ATOM 94   N N   . TYR A 1 35  ? 159.866 156.800 201.484 1.00 1.81  ? 19  TYR A N   1 
ATOM 95   C CA  . TYR A 1 35  ? 159.582 157.576 200.282 1.00 1.81  ? 19  TYR A CA  1 
ATOM 96   C C   . TYR A 1 35  ? 159.821 156.728 199.041 1.00 1.81  ? 19  TYR A C   1 
ATOM 97   O O   . TYR A 1 35  ? 160.086 155.526 199.148 1.00 1.81  ? 19  TYR A O   1 
ATOM 98   C CB  . TYR A 1 35  ? 160.420 158.855 200.220 1.00 1.81  ? 19  TYR A CB  1 
ATOM 99   C CG  . TYR A 1 35  ? 161.916 158.658 200.278 1.00 1.81  ? 19  TYR A CG  1 
ATOM 100  C CD1 . TYR A 1 35  ? 162.552 158.356 201.471 1.00 1.81  ? 19  TYR A CD1 1 
ATOM 101  C CD2 . TYR A 1 35  ? 162.693 158.788 199.137 1.00 1.81  ? 19  TYR A CD2 1 
ATOM 102  C CE1 . TYR A 1 35  ? 163.916 158.186 201.525 1.00 1.81  ? 19  TYR A CE1 1 
ATOM 103  C CE2 . TYR A 1 35  ? 164.060 158.618 199.183 1.00 1.81  ? 19  TYR A CE2 1 
ATOM 104  C CZ  . TYR A 1 35  ? 164.665 158.316 200.380 1.00 1.81  ? 19  TYR A CZ  1 
ATOM 105  O OH  . TYR A 1 35  ? 166.025 158.143 200.438 1.00 1.81  ? 19  TYR A OH  1 
ATOM 106  N N   . THR A 1 36  ? 159.726 157.340 197.860 1.00 1.63  ? 20  THR A N   1 
ATOM 107  C CA  . THR A 1 36  ? 159.902 156.598 196.608 1.00 1.63  ? 20  THR A CA  1 
ATOM 108  C C   . THR A 1 36  ? 161.056 157.250 195.837 1.00 1.63  ? 20  THR A C   1 
ATOM 109  O O   . THR A 1 36  ? 160.970 158.412 195.441 1.00 1.63  ? 20  THR A O   1 
ATOM 110  C CB  . THR A 1 36  ? 158.630 156.577 195.783 1.00 1.63  ? 20  THR A CB  1 
ATOM 111  O OG1 . THR A 1 36  ? 157.695 155.662 196.368 1.00 1.63  ? 20  THR A OG1 1 
ATOM 112  C CG2 . THR A 1 36  ? 158.927 156.140 194.357 1.00 1.63  ? 20  THR A CG2 1 
ATOM 113  N N   . PHE A 1 37  ? 162.128 156.485 195.645 1.00 2.40  ? 21  PHE A N   1 
ATOM 114  C CA  . PHE A 1 37  ? 163.254 156.946 194.846 1.00 2.40  ? 21  PHE A CA  1 
ATOM 115  C C   . PHE A 1 37  ? 162.849 157.085 193.385 1.00 2.40  ? 21  PHE A C   1 
ATOM 116  O O   . PHE A 1 37  ? 162.124 156.244 192.846 1.00 2.40  ? 21  PHE A O   1 
ATOM 117  C CB  . PHE A 1 37  ? 164.422 155.967 194.980 1.00 2.40  ? 21  PHE A CB  1 
ATOM 118  C CG  . PHE A 1 37  ? 165.768 156.583 194.725 1.00 2.40  ? 21  PHE A CG  1 
ATOM 119  C CD1 . PHE A 1 37  ? 165.903 157.949 194.557 1.00 2.40  ? 21  PHE A CD1 1 
ATOM 120  C CD2 . PHE A 1 37  ? 166.898 155.789 194.642 1.00 2.40  ? 21  PHE A CD2 1 
ATOM 121  C CE1 . PHE A 1 37  ? 167.142 158.511 194.319 1.00 2.40  ? 21  PHE A CE1 1 
ATOM 122  C CE2 . PHE A 1 37  ? 168.137 156.346 194.404 1.00 2.40  ? 21  PHE A CE2 1 
ATOM 123  C CZ  . PHE A 1 37  ? 168.259 157.708 194.241 1.00 2.40  ? 21  PHE A CZ  1 
ATOM 124  N N   . LYS A 1 38  ? 163.321 158.153 192.745 1.00 5.41  ? 22  LYS A N   1 
ATOM 125  C CA  . LYS A 1 38  ? 163.064 158.393 191.325 1.00 5.41  ? 22  LYS A CA  1 
ATOM 126  C C   . LYS A 1 38  ? 164.326 159.008 190.730 1.00 5.41  ? 22  LYS A C   1 
ATOM 127  O O   . LYS A 1 38  ? 164.535 160.221 190.822 1.00 5.41  ? 22  LYS A O   1 
ATOM 128  C CB  . LYS A 1 38  ? 161.854 159.295 191.121 1.00 5.41  ? 22  LYS A CB  1 
ATOM 129  C CG  . LYS A 1 38  ? 161.329 159.311 189.696 1.00 5.41  ? 22  LYS A CG  1 
ATOM 130  C CD  . LYS A 1 38  ? 160.240 158.269 189.498 1.00 5.41  ? 22  LYS A CD  1 
ATOM 131  C CE  . LYS A 1 38  ? 159.052 158.533 190.407 1.00 5.41  ? 22  LYS A CE  1 
ATOM 132  N NZ  . LYS A 1 38  ? 158.125 157.369 190.457 1.00 5.41  ? 22  LYS A NZ  1 
ATOM 133  N N   . ASP A 1 39  ? 165.160 158.170 190.123 1.00 12.05 ? 23  ASP A N   1 
ATOM 134  C CA  . ASP A 1 39  ? 166.425 158.612 189.560 1.00 12.05 ? 23  ASP A CA  1 
ATOM 135  C C   . ASP A 1 39  ? 166.247 159.039 188.109 1.00 12.05 ? 23  ASP A C   1 
ATOM 136  O O   . ASP A 1 39  ? 165.535 158.397 187.333 1.00 12.05 ? 23  ASP A O   1 
ATOM 137  C CB  . ASP A 1 39  ? 167.472 157.502 189.652 1.00 12.05 ? 23  ASP A CB  1 
ATOM 138  C CG  . ASP A 1 39  ? 168.882 158.015 189.451 1.00 12.05 ? 23  ASP A CG  1 
ATOM 139  O OD1 . ASP A 1 39  ? 169.062 159.248 189.371 1.00 12.05 ? 23  ASP A OD1 1 
ATOM 140  O OD2 . ASP A 1 39  ? 169.813 157.186 189.376 1.00 12.05 ? 23  ASP A OD2 1 
ATOM 141  N N   . ARG A 1 40  ? 166.909 160.138 187.749 1.00 22.14 ? 24  ARG A N   1 
ATOM 142  C CA  . ARG A 1 40  ? 166.860 160.680 186.398 1.00 22.14 ? 24  ARG A CA  1 
ATOM 143  C C   . ARG A 1 40  ? 168.070 160.265 185.568 1.00 22.14 ? 24  ARG A C   1 
ATOM 144  O O   . ARG A 1 40  ? 168.314 160.841 184.502 1.00 22.14 ? 24  ARG A O   1 
ATOM 145  C CB  . ARG A 1 40  ? 166.739 162.204 186.446 1.00 22.14 ? 24  ARG A CB  1 
ATOM 146  C CG  . ARG A 1 40  ? 166.029 162.813 185.244 1.00 22.14 ? 24  ARG A CG  1 
ATOM 147  C CD  . ARG A 1 40  ? 165.981 164.330 185.330 1.00 22.14 ? 24  ARG A CD  1 
ATOM 148  N NE  . ARG A 1 40  ? 165.395 164.923 184.134 1.00 22.14 ? 24  ARG A NE  1 
ATOM 149  C CZ  . ARG A 1 40  ? 164.108 165.206 183.990 1.00 22.14 ? 24  ARG A CZ  1 
ATOM 150  N NH1 . ARG A 1 40  ? 163.235 164.967 184.955 1.00 22.14 ? 24  ARG A NH1 1 
ATOM 151  N NH2 . ARG A 1 40  ? 163.685 165.741 182.848 1.00 22.14 ? 24  ARG A NH2 1 
ATOM 152  N N   . SER A 1 41  ? 168.830 159.276 186.033 1.00 17.42 ? 25  SER A N   1 
ATOM 153  C CA  . SER A 1 41  ? 169.997 158.774 185.320 1.00 17.42 ? 25  SER A CA  1 
ATOM 154  C C   . SER A 1 41  ? 169.772 157.349 184.825 1.00 17.42 ? 25  SER A C   1 
ATOM 155  O O   . SER A 1 41  ? 170.719 156.570 184.700 1.00 17.42 ? 25  SER A O   1 
ATOM 156  C CB  . SER A 1 41  ? 171.244 158.848 186.200 1.00 17.42 ? 25  SER A CB  1 
ATOM 157  O OG  . SER A 1 41  ? 171.427 160.155 186.714 1.00 17.42 ? 25  SER A OG  1 
ATOM 158  N N   . HIS A 1 42  ? 168.519 156.996 184.545 1.00 23.08 ? 26  HIS A N   1 
ATOM 159  C CA  . HIS A 1 42  ? 168.195 155.682 184.007 1.00 23.08 ? 26  HIS A CA  1 
ATOM 160  C C   . HIS A 1 42  ? 168.360 155.607 182.496 1.00 23.08 ? 26  HIS A C   1 
ATOM 161  O O   . HIS A 1 42  ? 168.204 154.523 181.925 1.00 23.08 ? 26  HIS A O   1 
ATOM 162  C CB  . HIS A 1 42  ? 166.766 155.290 184.395 1.00 23.08 ? 26  HIS A CB  1 
ATOM 163  C CG  . HIS A 1 42  ? 165.710 156.157 183.781 1.00 23.08 ? 26  HIS A CG  1 
ATOM 164  N ND1 . HIS A 1 42  ? 165.017 157.107 184.501 1.00 23.08 ? 26  HIS A ND1 1 
ATOM 165  C CD2 . HIS A 1 42  ? 165.219 156.209 182.520 1.00 23.08 ? 26  HIS A CD2 1 
ATOM 166  C CE1 . HIS A 1 42  ? 164.150 157.712 183.708 1.00 23.08 ? 26  HIS A CE1 1 
ATOM 167  N NE2 . HIS A 1 42  ? 164.253 157.186 182.500 1.00 23.08 ? 26  HIS A NE2 1 
ATOM 168  N N   . SER A 1 43  ? 168.660 156.724 181.838 1.00 15.80 ? 27  SER A N   1 
ATOM 169  C CA  . SER A 1 43  ? 168.933 156.750 180.407 1.00 15.80 ? 27  SER A CA  1 
ATOM 170  C C   . SER A 1 43  ? 170.380 157.078 180.084 1.00 15.80 ? 27  SER A C   1 
ATOM 171  O O   . SER A 1 43  ? 170.888 156.647 179.047 1.00 15.80 ? 27  SER A O   1 
ATOM 172  C CB  . SER A 1 43  ? 168.019 157.764 179.710 1.00 15.80 ? 27  SER A CB  1 
ATOM 173  O OG  . SER A 1 43  ? 168.177 157.708 178.303 1.00 15.80 ? 27  SER A OG  1 
ATOM 174  N N   . GLY A 1 44  ? 171.057 157.833 180.945 1.00 10.49 ? 28  GLY A N   1 
ATOM 175  C CA  . GLY A 1 44  ? 172.466 158.110 180.780 1.00 10.49 ? 28  GLY A CA  1 
ATOM 176  C C   . GLY A 1 44  ? 173.389 157.021 181.267 1.00 10.49 ? 28  GLY A C   1 
ATOM 177  O O   . GLY A 1 44  ? 174.611 157.157 181.161 1.00 10.49 ? 28  GLY A O   1 
ATOM 178  N N   . ARG A 1 45  ? 172.836 155.938 181.806 1.00 6.82  ? 29  ARG A N   1 
ATOM 179  C CA  . ARG A 1 45  ? 173.616 154.808 182.286 1.00 6.82  ? 29  ARG A CA  1 
ATOM 180  C C   . ARG A 1 45  ? 173.181 153.474 181.702 1.00 6.82  ? 29  ARG A C   1 
ATOM 181  O O   . ARG A 1 45  ? 173.952 152.514 181.758 1.00 6.82  ? 29  ARG A O   1 
ATOM 182  C CB  . ARG A 1 45  ? 173.545 154.722 183.818 1.00 6.82  ? 29  ARG A CB  1 
ATOM 183  C CG  . ARG A 1 45  ? 174.392 155.751 184.545 1.00 6.82  ? 29  ARG A CG  1 
ATOM 184  C CD  . ARG A 1 45  ? 174.833 155.227 185.902 1.00 6.82  ? 29  ARG A CD  1 
ATOM 185  N NE  . ARG A 1 45  ? 173.695 154.863 186.738 1.00 6.82  ? 29  ARG A NE  1 
ATOM 186  C CZ  . ARG A 1 45  ? 173.568 153.702 187.366 1.00 6.82  ? 29  ARG A CZ  1 
ATOM 187  N NH1 . ARG A 1 45  ? 174.494 152.762 187.275 1.00 6.82  ? 29  ARG A NH1 1 
ATOM 188  N NH2 . ARG A 1 45  ? 172.483 153.478 188.102 1.00 6.82  ? 29  ARG A NH2 1 
ATOM 189  N N   . VAL A 1 46  ? 171.974 153.383 181.153 1.00 7.29  ? 30  VAL A N   1 
ATOM 190  C CA  . VAL A 1 46  ? 171.475 152.146 180.571 1.00 7.29  ? 30  VAL A CA  1 
ATOM 191  C C   . VAL A 1 46  ? 171.388 152.234 179.053 1.00 7.29  ? 30  VAL A C   1 
ATOM 192  O O   . VAL A 1 46  ? 171.718 151.275 178.356 1.00 7.29  ? 30  VAL A O   1 
ATOM 193  C CB  . VAL A 1 46  ? 170.107 151.780 181.185 1.00 7.29  ? 30  VAL A CB  1 
ATOM 194  C CG1 . VAL A 1 46  ? 169.693 150.385 180.753 1.00 7.29  ? 30  VAL A CG1 1 
ATOM 195  C CG2 . VAL A 1 46  ? 170.165 151.881 182.697 1.00 7.29  ? 30  VAL A CG2 1 
ATOM 196  N N   . ALA A 1 47  ? 170.940 153.371 178.521 1.00 8.17  ? 31  ALA A N   1 
ATOM 197  C CA  . ALA A 1 47  ? 170.907 153.547 177.073 1.00 8.17  ? 31  ALA A CA  1 
ATOM 198  C C   . ALA A 1 47  ? 172.286 153.911 176.539 1.00 8.17  ? 31  ALA A C   1 
ATOM 199  O O   . ALA A 1 47  ? 172.862 153.183 175.724 1.00 8.17  ? 31  ALA A O   1 
ATOM 200  C CB  . ALA A 1 47  ? 169.883 154.618 176.694 1.00 8.17  ? 31  ALA A CB  1 
ATOM 201  N N   . GLN A 1 48  ? 172.832 155.040 176.993 1.00 7.05  ? 32  GLN A N   1 
ATOM 202  C CA  . GLN A 1 48  ? 174.199 155.399 176.641 1.00 7.05  ? 32  GLN A CA  1 
ATOM 203  C C   . GLN A 1 48  ? 175.210 154.440 177.252 1.00 7.05  ? 32  GLN A C   1 
ATOM 204  O O   . GLN A 1 48  ? 176.333 154.334 176.747 1.00 7.05  ? 32  GLN A O   1 
ATOM 205  C CB  . GLN A 1 48  ? 174.492 156.834 177.085 1.00 7.05  ? 32  GLN A CB  1 
ATOM 206  C CG  . GLN A 1 48  ? 175.754 157.436 176.489 1.00 7.05  ? 32  GLN A CG  1 
ATOM 207  C CD  . GLN A 1 48  ? 175.934 158.893 176.865 1.00 7.05  ? 32  GLN A CD  1 
ATOM 208  O OE1 . GLN A 1 48  ? 175.004 159.543 177.342 1.00 7.05  ? 32  GLN A OE1 1 
ATOM 209  N NE2 . GLN A 1 48  ? 177.136 159.415 176.652 1.00 7.05  ? 32  GLN A NE2 1 
ATOM 210  N N   . GLY A 1 49  ? 174.837 153.745 178.327 1.00 6.51  ? 33  GLY A N   1 
ATOM 211  C CA  . GLY A 1 49  ? 175.726 152.746 178.894 1.00 6.51  ? 33  GLY A CA  1 
ATOM 212  C C   . GLY A 1 49  ? 175.933 151.557 177.975 1.00 6.51  ? 33  GLY A C   1 
ATOM 213  O O   . GLY A 1 49  ? 177.045 151.034 177.866 1.00 6.51  ? 33  GLY A O   1 
ATOM 214  N N   . ILE A 1 50  ? 174.873 151.113 177.306 1.00 7.12  ? 34  ILE A N   1 
ATOM 215  C CA  . ILE A 1 50  ? 174.977 149.981 176.369 1.00 7.12  ? 34  ILE A CA  1 
ATOM 216  C C   . ILE A 1 50  ? 175.334 150.583 175.016 1.00 7.12  ? 34  ILE A C   1 
ATOM 217  O O   . ILE A 1 50  ? 174.509 150.729 174.111 1.00 7.12  ? 34  ILE A O   1 
ATOM 218  C CB  . ILE A 1 50  ? 173.697 149.139 176.331 1.00 7.12  ? 34  ILE A CB  1 
ATOM 219  C CG1 . ILE A 1 50  ? 173.327 148.664 177.735 1.00 7.12  ? 34  ILE A CG1 1 
ATOM 220  C CG2 . ILE A 1 50  ? 173.868 147.945 175.408 1.00 7.12  ? 34  ILE A CG2 1 
ATOM 221  C CD1 . ILE A 1 50  ? 172.088 147.799 177.774 1.00 7.12  ? 34  ILE A CD1 1 
ATOM 222  N N   . MET A 1 51  ? 176.610 150.934 174.876 1.00 7.21  ? 35  MET A N   1 
ATOM 223  C CA  . MET A 1 51  ? 177.229 151.278 173.598 1.00 7.21  ? 35  MET A CA  1 
ATOM 224  C C   . MET A 1 51  ? 178.593 150.644 173.413 1.00 7.21  ? 35  MET A C   1 
ATOM 225  O O   . MET A 1 51  ? 179.099 150.633 172.285 1.00 7.21  ? 35  MET A O   1 
ATOM 226  C CB  . MET A 1 51  ? 177.366 152.798 173.443 1.00 7.21  ? 35  MET A CB  1 
ATOM 227  C CG  . MET A 1 51  ? 176.062 153.545 173.211 1.00 7.21  ? 35  MET A CG  1 
ATOM 228  S SD  . MET A 1 51  ? 175.024 152.771 171.956 1.00 7.21  ? 35  MET A SD  1 
ATOM 229  C CE  . MET A 1 51  ? 173.417 153.421 172.399 1.00 7.21  ? 35  MET A CE  1 
ATOM 230  N N   . LYS A 1 52  ? 179.212 150.123 174.470 1.00 7.26  ? 36  LYS A N   1 
ATOM 231  C CA  . LYS A 1 52  ? 180.459 149.382 174.373 1.00 7.26  ? 36  LYS A CA  1 
ATOM 232  C C   . LYS A 1 52  ? 180.267 147.884 174.545 1.00 7.26  ? 36  LYS A C   1 
ATOM 233  O O   . LYS A 1 52  ? 181.076 147.107 174.035 1.00 7.26  ? 36  LYS A O   1 
ATOM 234  C CB  . LYS A 1 52  ? 181.455 149.882 175.424 1.00 7.26  ? 36  LYS A CB  1 
ATOM 235  C CG  . LYS A 1 52  ? 181.224 151.318 175.864 1.00 7.26  ? 36  LYS A CG  1 
ATOM 236  C CD  . LYS A 1 52  ? 182.065 151.663 177.082 1.00 7.26  ? 36  LYS A CD  1 
ATOM 237  C CE  . LYS A 1 52  ? 181.584 150.919 178.318 1.00 7.26  ? 36  LYS A CE  1 
ATOM 238  N NZ  . LYS A 1 52  ? 180.180 151.269 178.669 1.00 7.26  ? 36  LYS A NZ  1 
ATOM 239  N N   . LEU A 1 53  ? 179.217 147.462 175.251 1.00 5.33  ? 37  LEU A N   1 
ATOM 240  C CA  . LEU A 1 53  ? 178.958 146.041 175.434 1.00 5.33  ? 37  LEU A CA  1 
ATOM 241  C C   . LEU A 1 53  ? 178.172 145.430 174.284 1.00 5.33  ? 37  LEU A C   1 
ATOM 242  O O   . LEU A 1 53  ? 178.117 144.200 174.175 1.00 5.33  ? 37  LEU A O   1 
ATOM 243  C CB  . LEU A 1 53  ? 178.205 145.806 176.745 1.00 5.33  ? 37  LEU A CB  1 
ATOM 244  C CG  . LEU A 1 53  ? 178.835 146.401 178.002 1.00 5.33  ? 37  LEU A CG  1 
ATOM 245  C CD1 . LEU A 1 53  ? 177.864 146.333 179.166 1.00 5.33  ? 37  LEU A CD1 1 
ATOM 246  C CD2 . LEU A 1 53  ? 180.127 145.682 178.338 1.00 5.33  ? 37  LEU A CD2 1 
ATOM 247  N N   . CYS A 1 54  ? 177.567 146.249 173.426 1.00 4.20  ? 38  CYS A N   1 
ATOM 248  C CA  . CYS A 1 54  ? 176.744 145.759 172.328 1.00 4.20  ? 38  CYS A CA  1 
ATOM 249  C C   . CYS A 1 54  ? 177.299 146.117 170.959 1.00 4.20  ? 38  CYS A C   1 
ATOM 250  O O   . CYS A 1 54  ? 177.466 145.236 170.111 1.00 4.20  ? 38  CYS A O   1 
ATOM 251  C CB  . CYS A 1 54  ? 175.314 146.300 172.466 1.00 4.20  ? 38  CYS A CB  1 
ATOM 252  S SG  . CYS A 1 54  ? 174.163 145.685 171.219 1.00 4.20  ? 38  CYS A SG  1 
ATOM 253  N N   . LEU A 1 55  ? 177.595 147.394 170.716 1.00 5.17  ? 39  LEU A N   1 
ATOM 254  C CA  . LEU A 1 55  ? 178.037 147.836 169.397 1.00 5.17  ? 39  LEU A CA  1 
ATOM 255  C C   . LEU A 1 55  ? 179.556 147.779 169.249 1.00 5.17  ? 39  LEU A C   1 
ATOM 256  O O   . LEU A 1 55  ? 180.073 147.096 168.361 1.00 5.17  ? 39  LEU A O   1 
ATOM 257  C CB  . LEU A 1 55  ? 177.527 149.256 169.121 1.00 5.17  ? 39  LEU A CB  1 
ATOM 258  C CG  . LEU A 1 55  ? 176.014 149.468 169.155 1.00 5.17  ? 39  LEU A CG  1 
ATOM 259  C CD1 . LEU A 1 55  ? 175.658 150.834 168.598 1.00 5.17  ? 39  LEU A CD1 1 
ATOM 260  C CD2 . LEU A 1 55  ? 175.301 148.374 168.387 1.00 5.17  ? 39  LEU A CD2 1 
ATOM 261  N N   . GLU A 1 56  ? 180.281 148.491 170.114 1.00 8.33  ? 40  GLU A N   1 
ATOM 262  C CA  . GLU A 1 56  ? 181.727 148.604 169.951 1.00 8.33  ? 40  GLU A CA  1 
ATOM 263  C C   . GLU A 1 56  ? 182.424 147.282 170.252 1.00 8.33  ? 40  GLU A C   1 
ATOM 264  O O   . GLU A 1 56  ? 183.085 146.702 169.383 1.00 8.33  ? 40  GLU A O   1 
ATOM 265  C CB  . GLU A 1 56  ? 182.269 149.720 170.846 1.00 8.33  ? 40  GLU A CB  1 
ATOM 266  C CG  . GLU A 1 56  ? 183.788 149.809 170.871 1.00 8.33  ? 40  GLU A CG  1 
ATOM 267  C CD  . GLU A 1 56  ? 184.298 150.854 171.844 1.00 8.33  ? 40  GLU A CD  1 
ATOM 268  O OE1 . GLU A 1 56  ? 183.805 152.000 171.801 1.00 8.33  ? 40  GLU A OE1 1 
ATOM 269  O OE2 . GLU A 1 56  ? 185.195 150.530 172.651 1.00 8.33  ? 40  GLU A OE2 1 
ATOM 270  N N   . GLU A 1 57  ? 182.288 146.789 171.479 1.00 9.50  ? 41  GLU A N   1 
ATOM 271  C CA  . GLU A 1 57  ? 182.914 145.539 171.909 1.00 9.50  ? 41  GLU A CA  1 
ATOM 272  C C   . GLU A 1 57  ? 181.807 144.506 172.103 1.00 9.50  ? 41  GLU A C   1 
ATOM 273  O O   . GLU A 1 57  ? 181.233 144.385 173.186 1.00 9.50  ? 41  GLU A O   1 
ATOM 274  C CB  . GLU A 1 57  ? 183.722 145.741 173.189 1.00 9.50  ? 41  GLU A CB  1 
ATOM 275  C CG  . GLU A 1 57  ? 185.212 145.925 172.974 1.00 9.50  ? 41  GLU A CG  1 
ATOM 276  C CD  . GLU A 1 57  ? 185.988 145.912 174.276 1.00 9.50  ? 41  GLU A CD  1 
ATOM 277  O OE1 . GLU A 1 57  ? 185.352 146.007 175.347 1.00 9.50  ? 41  GLU A OE1 1 
ATOM 278  O OE2 . GLU A 1 57  ? 187.231 145.805 174.230 1.00 9.50  ? 41  GLU A OE2 1 
ATOM 279  N N   . GLU A 1 58  ? 181.510 143.761 171.041 1.00 7.07  ? 42  GLU A N   1 
ATOM 280  C CA  . GLU A 1 58  ? 180.490 142.724 171.117 1.00 7.07  ? 42  GLU A CA  1 
ATOM 281  C C   . GLU A 1 58  ? 180.934 141.624 172.071 1.00 7.07  ? 42  GLU A C   1 
ATOM 282  O O   . GLU A 1 58  ? 181.922 140.929 171.815 1.00 7.07  ? 42  GLU A O   1 
ATOM 283  C CB  . GLU A 1 58  ? 180.219 142.150 169.727 1.00 7.07  ? 42  GLU A CB  1 
ATOM 284  C CG  . GLU A 1 58  ? 179.907 143.196 168.669 1.00 7.07  ? 42  GLU A CG  1 
ATOM 285  C CD  . GLU A 1 58  ? 179.826 142.607 167.274 1.00 7.07  ? 42  GLU A CD  1 
ATOM 286  O OE1 . GLU A 1 58  ? 180.042 141.386 167.128 1.00 7.07  ? 42  GLU A OE1 1 
ATOM 287  O OE2 . GLU A 1 58  ? 179.547 143.365 166.322 1.00 7.07  ? 42  GLU A OE2 1 
ATOM 288  N N   . LEU A 1 59  ? 180.203 141.467 173.172 1.00 4.96  ? 43  LEU A N   1 
ATOM 289  C CA  . LEU A 1 59  ? 180.534 140.479 174.191 1.00 4.96  ? 43  LEU A CA  1 
ATOM 290  C C   . LEU A 1 59  ? 179.493 139.378 174.302 1.00 4.96  ? 43  LEU A C   1 
ATOM 291  O O   . LEU A 1 59  ? 179.846 138.193 174.273 1.00 4.96  ? 43  LEU A O   1 
ATOM 292  C CB  . LEU A 1 59  ? 180.715 141.167 175.554 1.00 4.96  ? 43  LEU A CB  1 
ATOM 293  C CG  . LEU A 1 59  ? 181.993 141.985 175.751 1.00 4.96  ? 43  LEU A CG  1 
ATOM 294  C CD1 . LEU A 1 59  ? 182.129 142.424 177.200 1.00 4.96  ? 43  LEU A CD1 1 
ATOM 295  C CD2 . LEU A 1 59  ? 183.213 141.191 175.314 1.00 4.96  ? 43  LEU A CD2 1 
ATOM 296  N N   . PHE A 1 60  ? 178.218 139.732 174.425 1.00 2.90  ? 44  PHE A N   1 
ATOM 297  C CA  . PHE A 1 60  ? 177.140 138.764 174.610 1.00 2.90  ? 44  PHE A CA  1 
ATOM 298  C C   . PHE A 1 60  ? 176.331 138.692 173.319 1.00 2.90  ? 44  PHE A C   1 
ATOM 299  O O   . PHE A 1 60  ? 175.560 139.604 173.006 1.00 2.90  ? 44  PHE A O   1 
ATOM 300  C CB  . PHE A 1 60  ? 176.266 139.153 175.798 1.00 2.90  ? 44  PHE A CB  1 
ATOM 301  C CG  . PHE A 1 60  ? 177.041 139.685 176.972 1.00 2.90  ? 44  PHE A CG  1 
ATOM 302  C CD1 . PHE A 1 60  ? 177.831 138.844 177.737 1.00 2.90  ? 44  PHE A CD1 1 
ATOM 303  C CD2 . PHE A 1 60  ? 176.979 141.026 177.311 1.00 2.90  ? 44  PHE A CD2 1 
ATOM 304  C CE1 . PHE A 1 60  ? 178.544 139.331 178.818 1.00 2.90  ? 44  PHE A CE1 1 
ATOM 305  C CE2 . PHE A 1 60  ? 177.689 141.517 178.392 1.00 2.90  ? 44  PHE A CE2 1 
ATOM 306  C CZ  . PHE A 1 60  ? 178.472 140.668 179.145 1.00 2.90  ? 44  PHE A CZ  1 
ATOM 307  N N   . ALA A 1 61  ? 176.505 137.602 172.576 1.00 2.80  ? 45  ALA A N   1 
ATOM 308  C CA  . ALA A 1 61  ? 175.804 137.374 171.322 1.00 2.80  ? 45  ALA A CA  1 
ATOM 309  C C   . ALA A 1 61  ? 174.849 136.196 171.466 1.00 2.80  ? 45  ALA A C   1 
ATOM 310  O O   . ALA A 1 61  ? 175.136 135.226 172.172 1.00 2.80  ? 45  ALA A O   1 
ATOM 311  C CB  . ALA A 1 61  ? 176.788 137.112 170.180 1.00 2.80  ? 45  ALA A CB  1 
ATOM 312  N N   . ASP A 1 62  ? 173.708 136.287 170.785 1.00 2.28  ? 46  ASP A N   1 
ATOM 313  C CA  . ASP A 1 62  ? 172.630 135.318 170.935 1.00 2.28  ? 46  ASP A CA  1 
ATOM 314  C C   . ASP A 1 62  ? 172.469 134.401 169.732 1.00 2.28  ? 46  ASP A C   1 
ATOM 315  O O   . ASP A 1 62  ? 172.533 133.177 169.880 1.00 2.28  ? 46  ASP A O   1 
ATOM 316  C CB  . ASP A 1 62  ? 171.305 136.048 171.203 1.00 2.28  ? 46  ASP A CB  1 
ATOM 317  C CG  . ASP A 1 62  ? 171.355 136.917 172.443 1.00 2.28  ? 46  ASP A CG  1 
ATOM 318  O OD1 . ASP A 1 62  ? 170.284 137.377 172.890 1.00 2.28  ? 46  ASP A OD1 1 
ATOM 319  O OD2 . ASP A 1 62  ? 172.462 137.142 172.973 1.00 2.28  ? 46  ASP A OD2 1 
ATOM 320  N N   . VAL A 1 63  ? 172.266 134.954 168.540 1.00 1.51  ? 47  VAL A N   1 
ATOM 321  C CA  . VAL A 1 63  ? 171.958 134.155 167.363 1.00 1.51  ? 47  VAL A CA  1 
ATOM 322  C C   . VAL A 1 63  ? 173.146 134.173 166.413 1.00 1.51  ? 47  VAL A C   1 
ATOM 323  O O   . VAL A 1 63  ? 173.979 135.084 166.426 1.00 1.51  ? 47  VAL A O   1 
ATOM 324  C CB  . VAL A 1 63  ? 170.685 134.646 166.645 1.00 1.51  ? 47  VAL A CB  1 
ATOM 325  C CG1 . VAL A 1 63  ? 169.501 134.627 167.596 1.00 1.51  ? 47  VAL A CG1 1 
ATOM 326  C CG2 . VAL A 1 63  ? 170.902 136.036 166.075 1.00 1.51  ? 47  VAL A CG2 1 
ATOM 327  N N   . THR A 1 64  ? 173.216 133.143 165.575 1.00 1.69  ? 48  THR A N   1 
ATOM 328  C CA  . THR A 1 64  ? 174.273 132.990 164.579 1.00 1.69  ? 48  THR A CA  1 
ATOM 329  C C   . THR A 1 64  ? 173.618 132.923 163.203 1.00 1.69  ? 48  THR A C   1 
ATOM 330  O O   . THR A 1 64  ? 173.288 131.842 162.712 1.00 1.69  ? 48  THR A O   1 
ATOM 331  C CB  . THR A 1 64  ? 175.120 131.749 164.850 1.00 1.69  ? 48  THR A CB  1 
ATOM 332  O OG1 . THR A 1 64  ? 174.276 130.592 164.887 1.00 1.69  ? 48  THR A OG1 1 
ATOM 333  C CG2 . THR A 1 64  ? 175.849 131.881 166.176 1.00 1.69  ? 48  THR A CG2 1 
ATOM 334  N N   . ILE A 1 65  ? 173.430 134.088 162.582 1.00 1.01  ? 49  ILE A N   1 
ATOM 335  C CA  . ILE A 1 65  ? 172.889 134.136 161.231 1.00 1.01  ? 49  ILE A CA  1 
ATOM 336  C C   . ILE A 1 65  ? 173.945 133.658 160.247 1.00 1.01  ? 49  ILE A C   1 
ATOM 337  O O   . ILE A 1 65  ? 175.101 134.100 160.281 1.00 1.01  ? 49  ILE A O   1 
ATOM 338  C CB  . ILE A 1 65  ? 172.409 135.556 160.890 1.00 1.01  ? 49  ILE A CB  1 
ATOM 339  C CG1 . ILE A 1 65  ? 171.425 136.051 161.946 1.00 1.01  ? 49  ILE A CG1 1 
ATOM 340  C CG2 . ILE A 1 65  ? 171.765 135.588 159.519 1.00 1.01  ? 49  ILE A CG2 1 
ATOM 341  C CD1 . ILE A 1 65  ? 171.145 137.525 161.860 1.00 1.01  ? 49  ILE A CD1 1 
ATOM 342  N N   . SER A 1 66  ? 173.554 132.744 159.365 1.00 1.26  ? 50  SER A N   1 
ATOM 343  C CA  . SER A 1 66  ? 174.457 132.155 158.385 1.00 1.26  ? 50  SER A CA  1 
ATOM 344  C C   . SER A 1 66  ? 174.077 132.658 157.002 1.00 1.26  ? 50  SER A C   1 
ATOM 345  O O   . SER A 1 66  ? 172.923 132.518 156.583 1.00 1.26  ? 50  SER A O   1 
ATOM 346  C CB  . SER A 1 66  ? 174.402 130.628 158.436 1.00 1.26  ? 50  SER A CB  1 
ATOM 347  O OG  . SER A 1 66  ? 175.339 130.054 157.542 1.00 1.26  ? 50  SER A OG  1 
ATOM 348  N N   . VAL A 1 67  ? 175.043 133.240 156.299 1.00 1.59  ? 51  VAL A N   1 
ATOM 349  C CA  . VAL A 1 67  ? 174.860 133.712 154.932 1.00 1.59  ? 51  VAL A CA  1 
ATOM 350  C C   . VAL A 1 67  ? 175.859 132.978 154.052 1.00 1.59  ? 51  VAL A C   1 
ATOM 351  O O   . VAL A 1 67  ? 177.074 133.109 154.245 1.00 1.59  ? 51  VAL A O   1 
ATOM 352  C CB  . VAL A 1 67  ? 175.047 135.231 154.821 1.00 1.59  ? 51  VAL A CB  1 
ATOM 353  C CG1 . VAL A 1 67  ? 175.103 135.646 153.363 1.00 1.59  ? 51  VAL A CG1 1 
ATOM 354  C CG2 . VAL A 1 67  ? 173.924 135.950 155.542 1.00 1.59  ? 51  VAL A CG2 1 
ATOM 355  N N   . GLU A 1 68  ? 175.348 132.222 153.080 1.00 2.20  ? 52  GLU A N   1 
ATOM 356  C CA  . GLU A 1 68  ? 176.161 131.390 152.184 1.00 2.20  ? 52  GLU A CA  1 
ATOM 357  C C   . GLU A 1 68  ? 177.043 130.496 153.058 1.00 2.20  ? 52  GLU A C   1 
ATOM 358  O O   . GLU A 1 68  ? 176.529 129.870 153.995 1.00 2.20  ? 52  GLU A O   1 
ATOM 359  C CB  . GLU A 1 68  ? 176.903 132.286 151.201 1.00 2.20  ? 52  GLU A CB  1 
ATOM 360  C CG  . GLU A 1 68  ? 176.868 131.799 149.764 1.00 2.20  ? 52  GLU A CG  1 
ATOM 361  C CD  . GLU A 1 68  ? 177.712 132.655 148.840 1.00 2.20  ? 52  GLU A CD  1 
ATOM 362  O OE1 . GLU A 1 68  ? 178.759 133.162 149.292 1.00 2.20  ? 52  GLU A OE1 1 
ATOM 363  O OE2 . GLU A 1 68  ? 177.329 132.821 147.664 1.00 2.20  ? 52  GLU A OE2 1 
ATOM 364  N N   . GLY A 1 69  ? 178.344 130.403 152.798 1.00 2.62  ? 53  GLY A N   1 
ATOM 365  C CA  . GLY A 1 69  ? 179.233 129.633 153.645 1.00 2.62  ? 53  GLY A CA  1 
ATOM 366  C C   . GLY A 1 69  ? 179.929 130.467 154.701 1.00 2.62  ? 53  GLY A C   1 
ATOM 367  O O   . GLY A 1 69  ? 181.157 130.586 154.692 1.00 2.62  ? 53  GLY A O   1 
ATOM 368  N N   . ARG A 1 70  ? 179.160 131.051 155.617 1.00 1.49  ? 54  ARG A N   1 
ATOM 369  C CA  . ARG A 1 70  ? 179.729 131.877 156.671 1.00 1.49  ? 54  ARG A CA  1 
ATOM 370  C C   . ARG A 1 70  ? 178.892 131.730 157.932 1.00 1.49  ? 54  ARG A C   1 
ATOM 371  O O   . ARG A 1 70  ? 177.752 131.260 157.895 1.00 1.49  ? 54  ARG A O   1 
ATOM 372  C CB  . ARG A 1 70  ? 179.809 133.351 156.259 1.00 1.49  ? 54  ARG A CB  1 
ATOM 373  C CG  . ARG A 1 70  ? 181.154 133.764 155.692 1.00 1.49  ? 54  ARG A CG  1 
ATOM 374  C CD  . ARG A 1 70  ? 181.200 135.259 155.427 1.00 1.49  ? 54  ARG A CD  1 
ATOM 375  N NE  . ARG A 1 70  ? 181.309 136.027 156.661 1.00 1.49  ? 54  ARG A NE  1 
ATOM 376  C CZ  . ARG A 1 70  ? 182.444 136.516 157.140 1.00 1.49  ? 54  ARG A CZ  1 
ATOM 377  N NH1 . ARG A 1 70  ? 183.593 136.340 156.508 1.00 1.49  ? 54  ARG A NH1 1 
ATOM 378  N NH2 . ARG A 1 70  ? 182.427 137.199 158.281 1.00 1.49  ? 54  ARG A NH2 1 
ATOM 379  N N   . GLU A 1 71  ? 179.480 132.135 159.055 1.00 1.10  ? 55  GLU A N   1 
ATOM 380  C CA  . GLU A 1 71  ? 178.823 132.091 160.357 1.00 1.10  ? 55  GLU A CA  1 
ATOM 381  C C   . GLU A 1 71  ? 179.000 133.443 161.034 1.00 1.10  ? 55  GLU A C   1 
ATOM 382  O O   . GLU A 1 71  ? 180.032 133.694 161.667 1.00 1.10  ? 55  GLU A O   1 
ATOM 383  C CB  . GLU A 1 71  ? 179.392 130.968 161.222 1.00 1.10  ? 55  GLU A CB  1 
ATOM 384  C CG  . GLU A 1 71  ? 179.244 129.580 160.622 1.00 1.10  ? 55  GLU A CG  1 
ATOM 385  C CD  . GLU A 1 71  ? 178.043 128.834 161.167 1.00 1.10  ? 55  GLU A CD  1 
ATOM 386  O OE1 . GLU A 1 71  ? 177.344 128.168 160.376 1.00 1.10  ? 55  GLU A OE1 1 
ATOM 387  O OE2 . GLU A 1 71  ? 177.798 128.914 162.389 1.00 1.10  ? 55  GLU A OE2 1 
ATOM 388  N N   . PHE A 1 72  ? 178.000 134.310 160.903 1.00 0.94  ? 56  PHE A N   1 
ATOM 389  C CA  . PHE A 1 72  ? 178.007 135.602 161.570 1.00 0.94  ? 56  PHE A CA  1 
ATOM 390  C C   . PHE A 1 72  ? 177.506 135.449 162.999 1.00 0.94  ? 56  PHE A C   1 
ATOM 391  O O   . PHE A 1 72  ? 176.648 134.610 163.281 1.00 0.94  ? 56  PHE A O   1 
ATOM 392  C CB  . PHE A 1 72  ? 177.134 136.608 160.820 1.00 0.94  ? 56  PHE A CB  1 
ATOM 393  C CG  . PHE A 1 72  ? 177.767 137.151 159.574 1.00 0.94  ? 56  PHE A CG  1 
ATOM 394  C CD1 . PHE A 1 72  ? 178.596 138.256 159.630 1.00 0.94  ? 56  PHE A CD1 1 
ATOM 395  C CD2 . PHE A 1 72  ? 177.528 136.561 158.347 1.00 0.94  ? 56  PHE A CD2 1 
ATOM 396  C CE1 . PHE A 1 72  ? 179.179 138.758 158.487 1.00 0.94  ? 56  PHE A CE1 1 
ATOM 397  C CE2 . PHE A 1 72  ? 178.108 137.059 157.201 1.00 0.94  ? 56  PHE A CE2 1 
ATOM 398  C CZ  . PHE A 1 72  ? 178.934 138.159 157.271 1.00 0.94  ? 56  PHE A CZ  1 
ATOM 399  N N   . GLN A 1 73  ? 178.051 136.261 163.898 1.00 0.91  ? 57  GLN A N   1 
ATOM 400  C CA  . GLN A 1 73  ? 177.648 136.277 165.302 1.00 0.91  ? 57  GLN A CA  1 
ATOM 401  C C   . GLN A 1 73  ? 176.993 137.626 165.573 1.00 0.91  ? 57  GLN A C   1 
ATOM 402  O O   . GLN A 1 73  ? 177.679 138.619 165.830 1.00 0.91  ? 57  GLN A O   1 
ATOM 403  C CB  . GLN A 1 73  ? 178.845 136.036 166.215 1.00 0.91  ? 57  GLN A CB  1 
ATOM 404  C CG  . GLN A 1 73  ? 178.501 135.340 167.518 1.00 0.91  ? 57  GLN A CG  1 
ATOM 405  C CD  . GLN A 1 73  ? 178.560 133.831 167.406 1.00 0.91  ? 57  GLN A CD  1 
ATOM 406  O OE1 . GLN A 1 73  ? 178.929 133.289 166.364 1.00 0.91  ? 57  GLN A OE1 1 
ATOM 407  N NE2 . GLN A 1 73  ? 178.198 133.142 168.481 1.00 0.91  ? 57  GLN A NE2 1 
ATOM 408  N N   . LEU A 1 74  ? 175.665 137.659 165.515 1.00 1.24  ? 58  LEU A N   1 
ATOM 409  C CA  . LEU A 1 74  ? 174.904 138.895 165.621 1.00 1.24  ? 58  LEU A CA  1 
ATOM 410  C C   . LEU A 1 74  ? 174.016 138.861 166.856 1.00 1.24  ? 58  LEU A C   1 
ATOM 411  O O   . LEU A 1 74  ? 173.452 137.818 167.200 1.00 1.24  ? 58  LEU A O   1 
ATOM 412  C CB  . LEU A 1 74  ? 174.046 139.123 164.374 1.00 1.24  ? 58  LEU A CB  1 
ATOM 413  C CG  . LEU A 1 74  ? 174.638 140.012 163.281 1.00 1.24  ? 58  LEU A CG  1 
ATOM 414  C CD1 . LEU A 1 74  ? 175.990 139.489 162.834 1.00 1.24  ? 58  LEU A CD1 1 
ATOM 415  C CD2 . LEU A 1 74  ? 173.688 140.106 162.103 1.00 1.24  ? 58  LEU A CD2 1 
ATOM 416  N N   . HIS A 1 75  ? 173.896 140.010 167.515 1.00 2.04  ? 59  HIS A N   1 
ATOM 417  C CA  . HIS A 1 75  ? 173.027 140.128 168.676 1.00 2.04  ? 59  HIS A CA  1 
ATOM 418  C C   . HIS A 1 75  ? 171.566 139.987 168.273 1.00 2.04  ? 59  HIS A C   1 
ATOM 419  O O   . HIS A 1 75  ? 171.171 140.303 167.149 1.00 2.04  ? 59  HIS A O   1 
ATOM 420  C CB  . HIS A 1 75  ? 173.237 141.474 169.368 1.00 2.04  ? 59  HIS A CB  1 
ATOM 421  C CG  . HIS A 1 75  ? 174.553 141.597 170.067 1.00 2.04  ? 59  HIS A CG  1 
ATOM 422  N ND1 . HIS A 1 75  ? 175.748 141.253 169.474 1.00 2.04  ? 59  HIS A ND1 1 
ATOM 423  C CD2 . HIS A 1 75  ? 174.863 142.038 171.309 1.00 2.04  ? 59  HIS A CD2 1 
ATOM 424  C CE1 . HIS A 1 75  ? 176.737 141.470 170.322 1.00 2.04  ? 59  HIS A CE1 1 
ATOM 425  N NE2 . HIS A 1 75  ? 176.227 141.946 171.443 1.00 2.04  ? 59  HIS A NE2 1 
ATOM 426  N N   . ARG A 1 76  ? 170.759 139.497 169.209 1.00 1.68  ? 60  ARG A N   1 
ATOM 427  C CA  . ARG A 1 76  ? 169.317 139.445 169.027 1.00 1.68  ? 60  ARG A CA  1 
ATOM 428  C C   . ARG A 1 76  ? 168.633 140.743 169.429 1.00 1.68  ? 60  ARG A C   1 
ATOM 429  O O   . ARG A 1 76  ? 167.412 140.856 169.278 1.00 1.68  ? 60  ARG A O   1 
ATOM 430  C CB  . ARG A 1 76  ? 168.725 138.285 169.834 1.00 1.68  ? 60  ARG A CB  1 
ATOM 431  C CG  . ARG A 1 76  ? 167.476 137.673 169.226 1.00 1.68  ? 60  ARG A CG  1 
ATOM 432  C CD  . ARG A 1 76  ? 166.638 136.972 170.281 1.00 1.68  ? 60  ARG A CD  1 
ATOM 433  N NE  . ARG A 1 76  ? 167.367 135.892 170.933 1.00 1.68  ? 60  ARG A NE  1 
ATOM 434  C CZ  . ARG A 1 76  ? 167.241 134.611 170.619 1.00 1.68  ? 60  ARG A CZ  1 
ATOM 435  N NH1 . ARG A 1 76  ? 166.418 134.210 169.665 1.00 1.68  ? 60  ARG A NH1 1 
ATOM 436  N NH2 . ARG A 1 76  ? 167.958 133.708 171.282 1.00 1.68  ? 60  ARG A NH2 1 
ATOM 437  N N   . LEU A 1 77  ? 169.389 141.720 169.926 1.00 0.89  ? 61  LEU A N   1 
ATOM 438  C CA  . LEU A 1 77  ? 168.818 142.941 170.485 1.00 0.89  ? 61  LEU A CA  1 
ATOM 439  C C   . LEU A 1 77  ? 168.879 144.106 169.501 1.00 0.89  ? 61  LEU A C   1 
ATOM 440  O O   . LEU A 1 77  ? 167.851 144.710 169.182 1.00 0.89  ? 61  LEU A O   1 
ATOM 441  C CB  . LEU A 1 77  ? 169.550 143.301 171.781 1.00 0.89  ? 61  LEU A CB  1 
ATOM 442  C CG  . LEU A 1 77  ? 168.770 143.168 173.085 1.00 0.89  ? 61  LEU A CG  1 
ATOM 443  C CD1 . LEU A 1 77  ? 169.519 143.873 174.195 1.00 0.89  ? 61  LEU A CD1 1 
ATOM 444  C CD2 . LEU A 1 77  ? 167.372 143.735 172.928 1.00 0.89  ? 61  LEU A CD2 1 
ATOM 445  N N   . VAL A 1 78  ? 170.080 144.432 169.018 1.00 0.66  ? 62  VAL A N   1 
ATOM 446  C CA  . VAL A 1 78  ? 170.239 145.610 168.171 1.00 0.66  ? 62  VAL A CA  1 
ATOM 447  C C   . VAL A 1 78  ? 169.601 145.395 166.804 1.00 0.66  ? 62  VAL A C   1 
ATOM 448  O O   . VAL A 1 78  ? 169.210 146.360 166.137 1.00 0.66  ? 62  VAL A O   1 
ATOM 449  C CB  . VAL A 1 78  ? 171.728 145.985 168.056 1.00 0.66  ? 62  VAL A CB  1 
ATOM 450  C CG1 . VAL A 1 78  ? 172.475 144.978 167.199 1.00 0.66  ? 62  VAL A CG1 1 
ATOM 451  C CG2 . VAL A 1 78  ? 171.881 147.389 167.501 1.00 0.66  ? 62  VAL A CG2 1 
ATOM 452  N N   . LEU A 1 79  ? 169.481 144.141 166.359 1.00 0.63  ? 63  LEU A N   1 
ATOM 453  C CA  . LEU A 1 79  ? 168.853 143.878 165.068 1.00 0.63  ? 63  LEU A CA  1 
ATOM 454  C C   . LEU A 1 79  ? 167.372 144.230 165.087 1.00 0.63  ? 63  LEU A C   1 
ATOM 455  O O   . LEU A 1 79  ? 166.854 144.806 164.124 1.00 0.63  ? 63  LEU A O   1 
ATOM 456  C CB  . LEU A 1 79  ? 169.048 142.415 164.677 1.00 0.63  ? 63  LEU A CB  1 
ATOM 457  C CG  . LEU A 1 79  ? 170.480 141.991 164.360 1.00 0.63  ? 63  LEU A CG  1 
ATOM 458  C CD1 . LEU A 1 79  ? 170.516 140.537 163.932 1.00 0.63  ? 63  LEU A CD1 1 
ATOM 459  C CD2 . LEU A 1 79  ? 171.073 142.883 163.289 1.00 0.63  ? 63  LEU A CD2 1 
ATOM 460  N N   . SER A 1 80  ? 166.673 143.897 166.173 1.00 0.64  ? 64  SER A N   1 
ATOM 461  C CA  . SER A 1 80  ? 165.242 144.151 166.257 1.00 0.64  ? 64  SER A CA  1 
ATOM 462  C C   . SER A 1 80  ? 164.909 145.600 166.586 1.00 0.64  ? 64  SER A C   1 
ATOM 463  O O   . SER A 1 80  ? 163.740 145.985 166.484 1.00 0.64  ? 64  SER A O   1 
ATOM 464  C CB  . SER A 1 80  ? 164.605 143.232 167.300 1.00 0.64  ? 64  SER A CB  1 
ATOM 465  O OG  . SER A 1 80  ? 164.935 141.877 167.051 1.00 0.64  ? 64  SER A OG  1 
ATOM 466  N N   . ALA A 1 81  ? 165.894 146.405 166.980 1.00 0.74  ? 65  ALA A N   1 
ATOM 467  C CA  . ALA A 1 81  ? 165.649 147.811 167.267 1.00 0.74  ? 65  ALA A CA  1 
ATOM 468  C C   . ALA A 1 81  ? 165.707 148.692 166.027 1.00 0.74  ? 65  ALA A C   1 
ATOM 469  O O   . ALA A 1 81  ? 165.294 149.854 166.096 1.00 0.74  ? 65  ALA A O   1 
ATOM 470  C CB  . ALA A 1 81  ? 166.653 148.321 168.303 1.00 0.74  ? 65  ALA A CB  1 
ATOM 471  N N   . GLN A 1 82  ? 166.203 148.176 164.903 1.00 2.12  ? 66  GLN A N   1 
ATOM 472  C CA  . GLN A 1 82  ? 166.290 148.932 163.660 1.00 2.12  ? 66  GLN A CA  1 
ATOM 473  C C   . GLN A 1 82  ? 165.419 148.356 162.555 1.00 2.12  ? 66  GLN A C   1 
ATOM 474  O O   . GLN A 1 82  ? 164.619 149.081 161.955 1.00 2.12  ? 66  GLN A O   1 
ATOM 475  C CB  . GLN A 1 82  ? 167.748 149.001 163.182 1.00 2.12  ? 66  GLN A CB  1 
ATOM 476  C CG  . GLN A 1 82  ? 168.744 149.364 164.266 1.00 2.12  ? 66  GLN A CG  1 
ATOM 477  C CD  . GLN A 1 82  ? 170.046 149.892 163.701 1.00 2.12  ? 66  GLN A CD  1 
ATOM 478  O OE1 . GLN A 1 82  ? 170.049 150.773 162.842 1.00 2.12  ? 66  GLN A OE1 1 
ATOM 479  N NE2 . GLN A 1 82  ? 171.161 149.358 164.182 1.00 2.12  ? 66  GLN A NE2 1 
ATOM 480  N N   . SER A 1 83  ? 165.553 147.065 162.268 1.00 1.67  ? 67  SER A N   1 
ATOM 481  C CA  . SER A 1 83  ? 164.809 146.412 161.194 1.00 1.67  ? 67  SER A CA  1 
ATOM 482  C C   . SER A 1 83  ? 163.656 145.634 161.815 1.00 1.67  ? 67  SER A C   1 
ATOM 483  O O   . SER A 1 83  ? 163.869 144.634 162.504 1.00 1.67  ? 67  SER A O   1 
ATOM 484  C CB  . SER A 1 83  ? 165.725 145.501 160.387 1.00 1.67  ? 67  SER A CB  1 
ATOM 485  O OG  . SER A 1 83  ? 165.948 144.283 161.071 1.00 1.67  ? 67  SER A OG  1 
ATOM 486  N N   . CYS A 1 84  ? 162.427 146.088 161.558 1.00 2.69  ? 68  CYS A N   1 
ATOM 487  C CA  . CYS A 1 84  ? 161.266 145.431 162.147 1.00 2.69  ? 68  CYS A CA  1 
ATOM 488  C C   . CYS A 1 84  ? 161.032 144.052 161.546 1.00 2.69  ? 68  CYS A C   1 
ATOM 489  O O   . CYS A 1 84  ? 160.335 143.226 162.146 1.00 2.69  ? 68  CYS A O   1 
ATOM 490  C CB  . CYS A 1 84  ? 160.020 146.297 161.973 1.00 2.69  ? 68  CYS A CB  1 
ATOM 491  S SG  . CYS A 1 84  ? 159.054 145.910 160.499 1.00 2.69  ? 68  CYS A SG  1 
ATOM 492  N N   . PHE A 1 85  ? 161.586 143.786 160.360 1.00 2.98  ? 69  PHE A N   1 
ATOM 493  C CA  . PHE A 1 85  ? 161.468 142.452 159.781 1.00 2.98  ? 69  PHE A CA  1 
ATOM 494  C C   . PHE A 1 85  ? 162.198 141.420 160.629 1.00 2.98  ? 69  PHE A C   1 
ATOM 495  O O   . PHE A 1 85  ? 161.695 140.311 160.842 1.00 2.98  ? 69  PHE A O   1 
ATOM 496  C CB  . PHE A 1 85  ? 162.004 142.441 158.351 1.00 2.98  ? 69  PHE A CB  1 
ATOM 497  C CG  . PHE A 1 85  ? 162.209 141.062 157.795 1.00 2.98  ? 69  PHE A CG  1 
ATOM 498  C CD1 . PHE A 1 85  ? 161.131 140.297 157.393 1.00 2.98  ? 69  PHE A CD1 1 
ATOM 499  C CD2 . PHE A 1 85  ? 163.480 140.530 157.678 1.00 2.98  ? 69  PHE A CD2 1 
ATOM 500  C CE1 . PHE A 1 85  ? 161.318 139.028 156.883 1.00 2.98  ? 69  PHE A CE1 1 
ATOM 501  C CE2 . PHE A 1 85  ? 163.673 139.262 157.169 1.00 2.98  ? 69  PHE A CE2 1 
ATOM 502  C CZ  . PHE A 1 85  ? 162.591 138.511 156.771 1.00 2.98  ? 69  PHE A CZ  1 
ATOM 503  N N   . PHE A 1 86  ? 163.393 141.764 161.118 1.00 2.52  ? 70  PHE A N   1 
ATOM 504  C CA  . PHE A 1 86  ? 164.110 140.861 162.010 1.00 2.52  ? 70  PHE A CA  1 
ATOM 505  C C   . PHE A 1 86  ? 163.377 140.694 163.334 1.00 2.52  ? 70  PHE A C   1 
ATOM 506  O O   . PHE A 1 86  ? 163.532 139.667 164.004 1.00 2.52  ? 70  PHE A O   1 
ATOM 507  C CB  . PHE A 1 86  ? 165.529 141.374 162.252 1.00 2.52  ? 70  PHE A CB  1 
ATOM 508  C CG  . PHE A 1 86  ? 166.530 140.890 161.244 1.00 2.52  ? 70  PHE A CG  1 
ATOM 509  C CD1 . PHE A 1 86  ? 166.415 139.633 160.682 1.00 2.52  ? 70  PHE A CD1 1 
ATOM 510  C CD2 . PHE A 1 86  ? 167.591 141.692 160.863 1.00 2.52  ? 70  PHE A CD2 1 
ATOM 511  C CE1 . PHE A 1 86  ? 167.336 139.186 159.759 1.00 2.52  ? 70  PHE A CE1 1 
ATOM 512  C CE2 . PHE A 1 86  ? 168.514 141.251 159.940 1.00 2.52  ? 70  PHE A CE2 1 
ATOM 513  C CZ  . PHE A 1 86  ? 168.386 139.997 159.387 1.00 2.52  ? 70  PHE A CZ  1 
ATOM 514  N N   . ARG A 1 87  ? 162.582 141.690 163.727 1.00 2.45  ? 71  ARG A N   1 
ATOM 515  C CA  . ARG A 1 87  ? 161.804 141.581 164.955 1.00 2.45  ? 71  ARG A CA  1 
ATOM 516  C C   . ARG A 1 87  ? 160.728 140.509 164.844 1.00 2.45  ? 71  ARG A C   1 
ATOM 517  O O   . ARG A 1 87  ? 160.433 139.826 165.830 1.00 2.45  ? 71  ARG A O   1 
ATOM 518  C CB  . ARG A 1 87  ? 161.174 142.930 165.297 1.00 2.45  ? 71  ARG A CB  1 
ATOM 519  C CG  . ARG A 1 87  ? 160.608 143.020 166.702 1.00 2.45  ? 71  ARG A CG  1 
ATOM 520  C CD  . ARG A 1 87  ? 160.111 144.426 166.998 1.00 2.45  ? 71  ARG A CD  1 
ATOM 521  N NE  . ARG A 1 87  ? 159.666 144.575 168.379 1.00 2.45  ? 71  ARG A NE  1 
ATOM 522  C CZ  . ARG A 1 87  ? 158.522 144.103 168.855 1.00 2.45  ? 71  ARG A CZ  1 
ATOM 523  N NH1 . ARG A 1 87  ? 157.671 143.444 168.087 1.00 2.45  ? 71  ARG A NH1 1 
ATOM 524  N NH2 . ARG A 1 87  ? 158.224 144.300 170.136 1.00 2.45  ? 71  ARG A NH2 1 
ATOM 525  N N   . SER A 1 88  ? 160.133 140.348 163.662 1.00 3.68  ? 72  SER A N   1 
ATOM 526  C CA  . SER A 1 88  ? 159.085 139.349 163.488 1.00 3.68  ? 72  SER A CA  1 
ATOM 527  C C   . SER A 1 88  ? 159.639 137.930 163.461 1.00 3.68  ? 72  SER A C   1 
ATOM 528  O O   . SER A 1 88  ? 158.970 137.003 163.929 1.00 3.68  ? 72  SER A O   1 
ATOM 529  C CB  . SER A 1 88  ? 158.297 139.628 162.208 1.00 3.68  ? 72  SER A CB  1 
ATOM 530  O OG  . SER A 1 88  ? 157.567 140.837 162.314 1.00 3.68  ? 72  SER A OG  1 
ATOM 531  N N   . MET A 1 89  ? 160.843 137.736 162.921 1.00 4.49  ? 73  MET A N   1 
ATOM 532  C CA  . MET A 1 89  ? 161.415 136.395 162.868 1.00 4.49  ? 73  MET A CA  1 
ATOM 533  C C   . MET A 1 89  ? 161.893 135.918 164.234 1.00 4.49  ? 73  MET A C   1 
ATOM 534  O O   . MET A 1 89  ? 161.833 134.717 164.520 1.00 4.49  ? 73  MET A O   1 
ATOM 535  C CB  . MET A 1 89  ? 162.570 136.349 161.867 1.00 4.49  ? 73  MET A CB  1 
ATOM 536  C CG  . MET A 1 89  ? 162.886 134.949 161.365 1.00 4.49  ? 73  MET A CG  1 
ATOM 537  S SD  . MET A 1 89  ? 164.544 134.784 160.675 1.00 4.49  ? 73  MET A SD  1 
ATOM 538  C CE  . MET A 1 89  ? 164.878 136.467 160.169 1.00 4.49  ? 73  MET A CE  1 
ATOM 539  N N   . PHE A 1 90  ? 162.368 136.830 165.084 1.00 4.22  ? 74  PHE A N   1 
ATOM 540  C CA  . PHE A 1 90  ? 162.848 136.434 166.403 1.00 4.22  ? 74  PHE A CA  1 
ATOM 541  C C   . PHE A 1 90  ? 161.704 136.278 167.398 1.00 4.22  ? 74  PHE A C   1 
ATOM 542  O O   . PHE A 1 90  ? 161.660 135.295 168.145 1.00 4.22  ? 74  PHE A O   1 
ATOM 543  C CB  . PHE A 1 90  ? 163.861 137.454 166.925 1.00 4.22  ? 74  PHE A CB  1 
ATOM 544  C CG  . PHE A 1 90  ? 165.162 137.461 166.174 1.00 4.22  ? 74  PHE A CG  1 
ATOM 545  C CD1 . PHE A 1 90  ? 165.677 136.294 165.640 1.00 4.22  ? 74  PHE A CD1 1 
ATOM 546  C CD2 . PHE A 1 90  ? 165.874 138.636 166.011 1.00 4.22  ? 74  PHE A CD2 1 
ATOM 547  C CE1 . PHE A 1 90  ? 166.875 136.301 164.953 1.00 4.22  ? 74  PHE A CE1 1 
ATOM 548  C CE2 . PHE A 1 90  ? 167.072 138.648 165.325 1.00 4.22  ? 74  PHE A CE2 1 
ATOM 549  C CZ  . PHE A 1 90  ? 167.572 137.479 164.796 1.00 4.22  ? 74  PHE A CZ  1 
ATOM 550  N N   . THR A 1 91  ? 160.776 137.238 167.426 1.00 6.52  ? 75  THR A N   1 
ATOM 551  C CA  . THR A 1 91  ? 159.698 137.204 168.411 1.00 6.52  ? 75  THR A CA  1 
ATOM 552  C C   . THR A 1 91  ? 158.768 136.018 168.190 1.00 6.52  ? 75  THR A C   1 
ATOM 553  O O   . THR A 1 91  ? 158.347 135.366 169.152 1.00 6.52  ? 75  THR A O   1 
ATOM 554  C CB  . THR A 1 91  ? 158.909 138.512 168.374 1.00 6.52  ? 75  THR A CB  1 
ATOM 555  O OG1 . THR A 1 91  ? 159.816 139.621 168.400 1.00 6.52  ? 75  THR A OG1 1 
ATOM 556  C CG2 . THR A 1 91  ? 157.972 138.604 169.568 1.00 6.52  ? 75  THR A CG2 1 
ATOM 557  N N   . SER A 1 92  ? 158.434 135.720 166.934 1.00 7.72  ? 76  SER A N   1 
ATOM 558  C CA  . SER A 1 92  ? 157.481 134.655 166.618 1.00 7.72  ? 76  SER A CA  1 
ATOM 559  C C   . SER A 1 92  ? 158.173 133.306 166.791 1.00 7.72  ? 76  SER A C   1 
ATOM 560  O O   . SER A 1 92  ? 158.635 132.672 165.838 1.00 7.72  ? 76  SER A O   1 
ATOM 561  C CB  . SER A 1 92  ? 156.926 134.827 165.210 1.00 7.72  ? 76  SER A CB  1 
ATOM 562  O OG  . SER A 1 92  ? 157.960 134.771 164.244 1.00 7.72  ? 76  SER A OG  1 
ATOM 563  N N   . ASN A 1 93  ? 158.245 132.863 168.044 1.00 11.52 ? 77  ASN A N   1 
ATOM 564  C CA  . ASN A 1 93  ? 158.810 131.556 168.346 1.00 11.52 ? 77  ASN A CA  1 
ATOM 565  C C   . ASN A 1 93  ? 157.915 130.453 167.794 1.00 11.52 ? 77  ASN A C   1 
ATOM 566  O O   . ASN A 1 93  ? 156.686 130.529 167.872 1.00 11.52 ? 77  ASN A O   1 
ATOM 567  C CB  . ASN A 1 93  ? 158.985 131.386 169.854 1.00 11.52 ? 77  ASN A CB  1 
ATOM 568  C CG  . ASN A 1 93  ? 159.864 132.460 170.465 1.00 11.52 ? 77  ASN A CG  1 
ATOM 569  O OD1 . ASN A 1 93  ? 159.370 133.454 170.996 1.00 11.52 ? 77  ASN A OD1 1 
ATOM 570  N ND2 . ASN A 1 93  ? 161.175 132.263 170.394 1.00 11.52 ? 77  ASN A ND2 1 
ATOM 571  N N   . LEU A 1 94  ? 158.540 129.422 167.233 1.00 19.96 ? 78  LEU A N   1 
ATOM 572  C CA  . LEU A 1 94  ? 157.810 128.315 166.631 1.00 19.96 ? 78  LEU A CA  1 
ATOM 573  C C   . LEU A 1 94  ? 158.646 127.048 166.786 1.00 19.96 ? 78  LEU A C   1 
ATOM 574  O O   . LEU A 1 94  ? 159.638 127.024 167.521 1.00 19.96 ? 78  LEU A O   1 
ATOM 575  C CB  . LEU A 1 94  ? 157.480 128.627 165.165 1.00 19.96 ? 78  LEU A CB  1 
ATOM 576  C CG  . LEU A 1 94  ? 156.177 128.051 164.606 1.00 19.96 ? 78  LEU A CG  1 
ATOM 577  C CD1 . LEU A 1 94  ? 155.000 128.433 165.491 1.00 19.96 ? 78  LEU A CD1 1 
ATOM 578  C CD2 . LEU A 1 94  ? 155.953 128.523 163.178 1.00 19.96 ? 78  LEU A CD2 1 
ATOM 579  N N   . LYS A 1 95  ? 158.236 125.985 166.089 1.00 20.61 ? 79  LYS A N   1 
ATOM 580  C CA  . LYS A 1 95  ? 158.962 124.722 166.151 1.00 20.61 ? 79  LYS A CA  1 
ATOM 581  C C   . LYS A 1 95  ? 160.361 124.828 165.560 1.00 20.61 ? 79  LYS A C   1 
ATOM 582  O O   . LYS A 1 95  ? 161.239 124.040 165.928 1.00 20.61 ? 79  LYS A O   1 
ATOM 583  C CB  . LYS A 1 95  ? 158.174 123.629 165.428 1.00 20.61 ? 79  LYS A CB  1 
ATOM 584  C CG  . LYS A 1 95  ? 157.737 124.008 164.022 1.00 20.61 ? 79  LYS A CG  1 
ATOM 585  C CD  . LYS A 1 95  ? 157.263 122.793 163.243 1.00 20.61 ? 79  LYS A CD  1 
ATOM 586  C CE  . LYS A 1 95  ? 156.871 123.167 161.823 1.00 20.61 ? 79  LYS A CE  1 
ATOM 587  N NZ  . LYS A 1 95  ? 155.733 124.127 161.795 1.00 20.61 ? 79  LYS A NZ  1 
ATOM 588  N N   . GLU A 1 96  ? 160.590 125.779 164.658 1.00 25.31 ? 80  GLU A N   1 
ATOM 589  C CA  . GLU A 1 96  ? 161.893 125.973 164.039 1.00 25.31 ? 80  GLU A CA  1 
ATOM 590  C C   . GLU A 1 96  ? 162.756 126.986 164.780 1.00 25.31 ? 80  GLU A C   1 
ATOM 591  O O   . GLU A 1 96  ? 163.836 127.333 164.292 1.00 25.31 ? 80  GLU A O   1 
ATOM 592  C CB  . GLU A 1 96  ? 161.725 126.408 162.579 1.00 25.31 ? 80  GLU A CB  1 
ATOM 593  C CG  . GLU A 1 96  ? 160.891 127.664 162.396 1.00 25.31 ? 80  GLU A CG  1 
ATOM 594  C CD  . GLU A 1 96  ? 160.681 128.014 160.936 1.00 25.31 ? 80  GLU A CD  1 
ATOM 595  O OE1 . GLU A 1 96  ? 160.783 127.105 160.085 1.00 25.31 ? 80  GLU A OE1 1 
ATOM 596  O OE2 . GLU A 1 96  ? 160.413 129.197 160.638 1.00 25.31 ? 80  GLU A OE2 1 
ATOM 597  N N   . ALA A 1 97  ? 162.307 127.469 165.936 1.00 20.36 ? 81  ALA A N   1 
ATOM 598  C CA  . ALA A 1 97  ? 163.066 128.415 166.742 1.00 20.36 ? 81  ALA A CA  1 
ATOM 599  C C   . ALA A 1 97  ? 163.960 127.732 167.769 1.00 20.36 ? 81  ALA A C   1 
ATOM 600  O O   . ALA A 1 97  ? 164.614 128.420 168.560 1.00 20.36 ? 81  ALA A O   1 
ATOM 601  C CB  . ALA A 1 97  ? 162.117 129.388 167.446 1.00 20.36 ? 81  ALA A CB  1 
ATOM 602  N N   . HIS A 1 98  ? 164.002 126.400 167.777 1.00 22.82 ? 82  HIS A N   1 
ATOM 603  C CA  . HIS A 1 98  ? 164.815 125.655 168.728 1.00 22.82 ? 82  HIS A CA  1 
ATOM 604  C C   . HIS A 1 98  ? 166.300 125.671 168.391 1.00 22.82 ? 82  HIS A C   1 
ATOM 605  O O   . HIS A 1 98  ? 167.117 125.334 169.254 1.00 22.82 ? 82  HIS A O   1 
ATOM 606  C CB  . HIS A 1 98  ? 164.330 124.204 168.812 1.00 22.82 ? 82  HIS A CB  1 
ATOM 607  C CG  . HIS A 1 98  ? 164.759 123.494 170.058 1.00 22.82 ? 82  HIS A CG  1 
ATOM 608  N ND1 . HIS A 1 98  ? 165.102 122.159 170.073 1.00 22.82 ? 82  HIS A ND1 1 
ATOM 609  C CD2 . HIS A 1 98  ? 164.900 123.934 171.331 1.00 22.82 ? 82  HIS A CD2 1 
ATOM 610  C CE1 . HIS A 1 98  ? 165.437 121.807 171.302 1.00 22.82 ? 82  HIS A CE1 1 
ATOM 611  N NE2 . HIS A 1 98  ? 165.322 122.866 172.084 1.00 22.82 ? 82  HIS A NE2 1 
ATOM 612  N N   . ASN A 1 99  ? 166.667 126.052 167.172 1.00 19.04 ? 83  ASN A N   1 
ATOM 613  C CA  . ASN A 1 99  ? 168.057 126.109 166.750 1.00 19.04 ? 83  ASN A CA  1 
ATOM 614  C C   . ASN A 1 99  ? 168.510 127.559 166.625 1.00 19.04 ? 83  ASN A C   1 
ATOM 615  O O   . ASN A 1 99  ? 167.722 128.458 166.317 1.00 19.04 ? 83  ASN A O   1 
ATOM 616  C CB  . ASN A 1 99  ? 168.262 125.371 165.421 1.00 19.04 ? 83  ASN A CB  1 
ATOM 617  C CG  . ASN A 1 99  ? 167.658 126.110 164.241 1.00 19.04 ? 83  ASN A CG  1 
ATOM 618  O OD1 . ASN A 1 99  ? 166.609 126.743 164.359 1.00 19.04 ? 83  ASN A OD1 1 
ATOM 619  N ND2 . ASN A 1 99  ? 168.321 126.030 163.094 1.00 19.04 ? 83  ASN A ND2 1 
ATOM 620  N N   . ARG A 1 100 ? 169.799 127.777 166.878 1.00 14.81 ? 84  ARG A N   1 
ATOM 621  C CA  . ARG A 1 100 ? 170.384 129.110 166.856 1.00 14.81 ? 84  ARG A CA  1 
ATOM 622  C C   . ARG A 1 100 ? 171.119 129.409 165.556 1.00 14.81 ? 84  ARG A C   1 
ATOM 623  O O   . ARG A 1 100 ? 171.841 130.408 165.480 1.00 14.81 ? 84  ARG A O   1 
ATOM 624  C CB  . ARG A 1 100 ? 171.326 129.294 168.048 1.00 14.81 ? 84  ARG A CB  1 
ATOM 625  C CG  . ARG A 1 100 ? 172.543 128.386 168.030 1.00 14.81 ? 84  ARG A CG  1 
ATOM 626  C CD  . ARG A 1 100 ? 173.408 128.611 169.259 1.00 14.81 ? 84  ARG A CD  1 
ATOM 627  N NE  . ARG A 1 100 ? 174.535 127.688 169.315 1.00 14.81 ? 84  ARG A NE  1 
ATOM 628  C CZ  . ARG A 1 100 ? 174.502 126.501 169.904 1.00 14.81 ? 84  ARG A CZ  1 
ATOM 629  N NH1 . ARG A 1 100 ? 173.407 126.054 170.497 1.00 14.81 ? 84  ARG A NH1 1 
ATOM 630  N NH2 . ARG A 1 100 ? 175.595 125.742 169.897 1.00 14.81 ? 84  ARG A NH2 1 
ATOM 631  N N   . VAL A 1 101 ? 170.960 128.571 164.538 1.00 8.27  ? 85  VAL A N   1 
ATOM 632  C CA  . VAL A 1 101 ? 171.542 128.807 163.223 1.00 8.27  ? 85  VAL A CA  1 
ATOM 633  C C   . VAL A 1 101 ? 170.387 129.169 162.297 1.00 8.27  ? 85  VAL A C   1 
ATOM 634  O O   . VAL A 1 101 ? 169.479 128.361 162.067 1.00 8.27  ? 85  VAL A O   1 
ATOM 635  C CB  . VAL A 1 101 ? 172.327 127.594 162.711 1.00 8.27  ? 85  VAL A CB  1 
ATOM 636  C CG1 . VAL A 1 101 ? 172.343 127.561 161.188 1.00 8.27  ? 85  VAL A CG1 1 
ATOM 637  C CG2 . VAL A 1 101 ? 173.745 127.612 163.259 1.00 8.27  ? 85  VAL A CG2 1 
ATOM 638  N N   . ILE A 1 102 ? 170.404 130.394 161.782 1.00 3.81  ? 86  ILE A N   1 
ATOM 639  C CA  . ILE A 1 102 ? 169.367 130.892 160.887 1.00 3.81  ? 86  ILE A CA  1 
ATOM 640  C C   . ILE A 1 102 ? 170.003 131.149 159.530 1.00 3.81  ? 86  ILE A C   1 
ATOM 641  O O   . ILE A 1 102 ? 170.976 131.905 159.425 1.00 3.81  ? 86  ILE A O   1 
ATOM 642  C CB  . ILE A 1 102 ? 168.711 132.165 161.442 1.00 3.81  ? 86  ILE A CB  1 
ATOM 643  C CG1 . ILE A 1 102 ? 168.087 131.886 162.809 1.00 3.81  ? 86  ILE A CG1 1 
ATOM 644  C CG2 . ILE A 1 102 ? 167.666 132.689 160.474 1.00 3.81  ? 86  ILE A CG2 1 
ATOM 645  C CD1 . ILE A 1 102 ? 167.540 133.116 163.492 1.00 3.81  ? 86  ILE A CD1 1 
ATOM 646  N N   . VAL A 1 103 ? 169.462 130.525 158.494 1.00 4.41  ? 87  VAL A N   1 
ATOM 647  C CA  . VAL A 1 103 ? 170.008 130.639 157.148 1.00 4.41  ? 87  VAL A CA  1 
ATOM 648  C C   . VAL A 1 103 ? 169.273 131.736 156.394 1.00 4.41  ? 87  VAL A C   1 
ATOM 649  O O   . VAL A 1 103 ? 168.055 131.902 156.533 1.00 4.41  ? 87  VAL A O   1 
ATOM 650  C CB  . VAL A 1 103 ? 169.915 129.294 156.403 1.00 4.41  ? 87  VAL A CB  1 
ATOM 651  C CG1 . VAL A 1 103 ? 170.985 128.339 156.902 1.00 4.41  ? 87  VAL A CG1 1 
ATOM 652  C CG2 . VAL A 1 103 ? 168.533 128.687 156.576 1.00 4.41  ? 87  VAL A CG2 1 
ATOM 653  N N   . LEU A 1 104 ? 170.019 132.495 155.598 1.00 5.53  ? 88  LEU A N   1 
ATOM 654  C CA  . LEU A 1 104 ? 169.465 133.506 154.712 1.00 5.53  ? 88  LEU A CA  1 
ATOM 655  C C   . LEU A 1 104 ? 169.753 133.123 153.267 1.00 5.53  ? 88  LEU A C   1 
ATOM 656  O O   . LEU A 1 104 ? 170.739 132.442 152.974 1.00 5.53  ? 88  LEU A O   1 
ATOM 657  C CB  . LEU A 1 104 ? 170.042 134.891 155.017 1.00 5.53  ? 88  LEU A CB  1 
ATOM 658  C CG  . LEU A 1 104 ? 169.640 135.500 156.361 1.00 5.53  ? 88  LEU A CG  1 
ATOM 659  C CD1 . LEU A 1 104 ? 170.063 136.954 156.432 1.00 5.53  ? 88  LEU A CD1 1 
ATOM 660  C CD2 . LEU A 1 104 ? 168.145 135.366 156.585 1.00 5.53  ? 88  LEU A CD2 1 
ATOM 661  N N   . GLN A 1 105 ? 168.885 133.564 152.365 1.00 7.28  ? 89  GLN A N   1 
ATOM 662  C CA  . GLN A 1 105 ? 168.935 133.108 150.982 1.00 7.28  ? 89  GLN A CA  1 
ATOM 663  C C   . GLN A 1 105 ? 169.147 134.224 149.973 1.00 7.28  ? 89  GLN A C   1 
ATOM 664  O O   . GLN A 1 105 ? 169.907 134.044 149.018 1.00 7.28  ? 89  GLN A O   1 
ATOM 665  C CB  . GLN A 1 105 ? 167.641 132.356 150.639 1.00 7.28  ? 89  GLN A CB  1 
ATOM 666  C CG  . GLN A 1 105 ? 167.326 131.207 151.584 1.00 7.28  ? 89  GLN A CG  1 
ATOM 667  C CD  . GLN A 1 105 ? 166.015 130.522 151.254 1.00 7.28  ? 89  GLN A CD  1 
ATOM 668  O OE1 . GLN A 1 105 ? 165.507 130.631 150.138 1.00 7.28  ? 89  GLN A OE1 1 
ATOM 669  N NE2 . GLN A 1 105 ? 165.458 129.811 152.227 1.00 7.28  ? 89  GLN A NE2 1 
ATOM 670  N N   . ASP A 1 106 ? 168.498 135.371 150.150 1.00 7.07  ? 90  ASP A N   1 
ATOM 671  C CA  . ASP A 1 106 ? 168.515 136.434 149.156 1.00 7.07  ? 90  ASP A CA  1 
ATOM 672  C C   . ASP A 1 106 ? 169.844 137.185 149.123 1.00 7.07  ? 90  ASP A C   1 
ATOM 673  O O   . ASP A 1 106 ? 170.358 137.462 148.035 1.00 7.07  ? 90  ASP A O   1 
ATOM 674  C CB  . ASP A 1 106 ? 167.360 137.408 149.424 1.00 7.07  ? 90  ASP A CB  1 
ATOM 675  C CG  . ASP A 1 106 ? 167.419 138.665 148.563 1.00 7.07  ? 90  ASP A CG  1 
ATOM 676  O OD1 . ASP A 1 106 ? 166.754 139.655 148.928 1.00 7.07  ? 90  ASP A OD1 1 
ATOM 677  O OD2 . ASP A 1 106 ? 168.059 138.656 147.491 1.00 7.07  ? 90  ASP A OD2 1 
ATOM 678  N N   . VAL A 1 107 ? 170.427 137.488 150.280 1.00 5.12  ? 91  VAL A N   1 
ATOM 679  C CA  . VAL A 1 107 ? 171.599 138.351 150.374 1.00 5.12  ? 91  VAL A CA  1 
ATOM 680  C C   . VAL A 1 107 ? 172.841 137.534 150.052 1.00 5.12  ? 91  VAL A C   1 
ATOM 681  O O   . VAL A 1 107 ? 172.876 136.321 150.291 1.00 5.12  ? 91  VAL A O   1 
ATOM 682  C CB  . VAL A 1 107 ? 171.710 139.009 151.762 1.00 5.12  ? 91  VAL A CB  1 
ATOM 683  C CG1 . VAL A 1 107 ? 170.347 139.487 152.223 1.00 5.12  ? 91  VAL A CG1 1 
ATOM 684  C CG2 . VAL A 1 107 ? 172.298 138.044 152.776 1.00 5.12  ? 91  VAL A CG2 1 
ATOM 685  N N   . SER A 1 108 ? 173.842 138.193 149.475 1.00 4.65  ? 92  SER A N   1 
ATOM 686  C CA  . SER A 1 108 ? 175.095 137.545 149.129 1.00 4.65  ? 92  SER A CA  1 
ATOM 687  C C   . SER A 1 108 ? 176.072 137.604 150.302 1.00 4.65  ? 92  SER A C   1 
ATOM 688  O O   . SER A 1 108 ? 175.776 138.141 151.372 1.00 4.65  ? 92  SER A O   1 
ATOM 689  C CB  . SER A 1 108 ? 175.711 138.198 147.892 1.00 4.65  ? 92  SER A CB  1 
ATOM 690  O OG  . SER A 1 108 ? 174.869 138.044 146.764 1.00 4.65  ? 92  SER A OG  1 
ATOM 691  N N   . GLU A 1 109 ? 177.258 137.037 150.085 1.00 3.61  ? 93  GLU A N   1 
ATOM 692  C CA  . GLU A 1 109 ? 178.289 137.020 151.115 1.00 3.61  ? 93  GLU A CA  1 
ATOM 693  C C   . GLU A 1 109 ? 178.956 138.374 151.311 1.00 3.61  ? 93  GLU A C   1 
ATOM 694  O O   . GLU A 1 109 ? 179.277 138.729 152.450 1.00 3.61  ? 93  GLU A O   1 
ATOM 695  C CB  . GLU A 1 109 ? 179.352 135.976 150.771 1.00 3.61  ? 93  GLU A CB  1 
ATOM 696  C CG  . GLU A 1 109 ? 180.268 135.613 151.924 1.00 3.61  ? 93  GLU A CG  1 
ATOM 697  C CD  . GLU A 1 109 ? 181.306 134.579 151.534 1.00 3.61  ? 93  GLU A CD  1 
ATOM 698  O OE1 . GLU A 1 109 ? 181.431 134.291 150.326 1.00 3.61  ? 93  GLU A OE1 1 
ATOM 699  O OE2 . GLU A 1 109 ? 181.998 134.058 152.433 1.00 3.61  ? 93  GLU A OE2 1 
ATOM 700  N N   . SER A 1 110 ? 179.174 139.132 150.238 1.00 2.60  ? 94  SER A N   1 
ATOM 701  C CA  . SER A 1 110 ? 179.863 140.412 150.313 1.00 2.60  ? 94  SER A CA  1 
ATOM 702  C C   . SER A 1 110 ? 178.916 141.596 150.430 1.00 2.60  ? 94  SER A C   1 
ATOM 703  O O   . SER A 1 110 ? 179.381 142.739 150.484 1.00 2.60  ? 94  SER A O   1 
ATOM 704  C CB  . SER A 1 110 ? 180.768 140.600 149.091 1.00 2.60  ? 94  SER A CB  1 
ATOM 705  O OG  . SER A 1 110 ? 181.436 141.848 149.145 1.00 2.60  ? 94  SER A OG  1 
ATOM 706  N N   . VAL A 1 111 ? 177.608 141.359 150.462 1.00 1.70  ? 95  VAL A N   1 
ATOM 707  C CA  . VAL A 1 111 ? 176.638 142.425 150.668 1.00 1.70  ? 95  VAL A CA  1 
ATOM 708  C C   . VAL A 1 111 ? 176.089 142.440 152.088 1.00 1.70  ? 95  VAL A C   1 
ATOM 709  O O   . VAL A 1 111 ? 175.899 143.532 152.647 1.00 1.70  ? 95  VAL A O   1 
ATOM 710  C CB  . VAL A 1 111 ? 175.486 142.331 149.645 1.00 1.70  ? 95  VAL A CB  1 
ATOM 711  C CG1 . VAL A 1 111 ? 174.273 143.122 150.109 1.00 1.70  ? 95  VAL A CG1 1 
ATOM 712  C CG2 . VAL A 1 111 ? 175.957 142.817 148.287 1.00 1.70  ? 95  VAL A CG2 1 
ATOM 713  N N   . PHE A 1 112 ? 175.860 141.277 152.700 1.00 2.18  ? 96  PHE A N   1 
ATOM 714  C CA  . PHE A 1 112 ? 175.414 141.237 154.087 1.00 2.18  ? 96  PHE A CA  1 
ATOM 715  C C   . PHE A 1 112 ? 176.430 141.862 155.032 1.00 2.18  ? 96  PHE A C   1 
ATOM 716  O O   . PHE A 1 112 ? 176.041 142.475 156.031 1.00 2.18  ? 96  PHE A O   1 
ATOM 717  C CB  . PHE A 1 112 ? 175.130 139.796 154.509 1.00 2.18  ? 96  PHE A CB  1 
ATOM 718  C CG  . PHE A 1 112 ? 174.350 139.683 155.784 1.00 2.18  ? 96  PHE A CG  1 
ATOM 719  C CD1 . PHE A 1 112 ? 173.067 140.189 155.873 1.00 2.18  ? 96  PHE A CD1 1 
ATOM 720  C CD2 . PHE A 1 112 ? 174.903 139.076 156.897 1.00 2.18  ? 96  PHE A CD2 1 
ATOM 721  C CE1 . PHE A 1 112 ? 172.349 140.090 157.045 1.00 2.18  ? 96  PHE A CE1 1 
ATOM 722  C CE2 . PHE A 1 112 ? 174.189 138.974 158.071 1.00 2.18  ? 96  PHE A CE2 1 
ATOM 723  C CZ  . PHE A 1 112 ? 172.910 139.482 158.145 1.00 2.18  ? 96  PHE A CZ  1 
ATOM 724  N N   . GLN A 1 113 ? 177.725 141.718 154.742 1.00 9.84  ? 97  GLN A N   1 
ATOM 725  C CA  . GLN A 1 113 ? 178.739 142.347 155.582 1.00 9.84  ? 97  GLN A CA  1 
ATOM 726  C C   . GLN A 1 113 ? 178.610 143.864 155.556 1.00 9.84  ? 97  GLN A C   1 
ATOM 727  O O   . GLN A 1 113 ? 178.755 144.523 156.591 1.00 9.84  ? 97  GLN A O   1 
ATOM 728  C CB  . GLN A 1 113 ? 180.135 141.918 155.136 1.00 9.84  ? 97  GLN A CB  1 
ATOM 729  C CG  . GLN A 1 113 ? 181.228 142.270 156.127 1.00 9.84  ? 97  GLN A CG  1 
ATOM 730  C CD  . GLN A 1 113 ? 182.571 141.687 155.740 1.00 9.84  ? 97  GLN A CD  1 
ATOM 731  O OE1 . GLN A 1 113 ? 182.846 141.462 154.561 1.00 9.84  ? 97  GLN A OE1 1 
ATOM 732  N NE2 . GLN A 1 113 ? 183.417 141.439 156.732 1.00 9.84  ? 97  GLN A NE2 1 
ATOM 733  N N   . LEU A 1 114 ? 178.344 144.438 154.380 1.00 2.90  ? 98  LEU A N   1 
ATOM 734  C CA  . LEU A 1 114 ? 178.069 145.870 154.309 1.00 2.90  ? 98  LEU A CA  1 
ATOM 735  C C   . LEU A 1 114 ? 176.810 146.229 155.084 1.00 2.90  ? 98  LEU A C   1 
ATOM 736  O O   . LEU A 1 114 ? 176.738 147.307 155.683 1.00 2.90  ? 98  LEU A O   1 
ATOM 737  C CB  . LEU A 1 114 ? 177.935 146.318 152.854 1.00 2.90  ? 98  LEU A CB  1 
ATOM 738  C CG  . LEU A 1 114 ? 179.163 146.942 152.189 1.00 2.90  ? 98  LEU A CG  1 
ATOM 739  C CD1 . LEU A 1 114 ? 180.364 146.015 152.275 1.00 2.90  ? 98  LEU A CD1 1 
ATOM 740  C CD2 . LEU A 1 114 ? 178.863 147.301 150.744 1.00 2.90  ? 98  LEU A CD2 1 
ATOM 741  N N   . LEU A 1 115 ? 175.809 145.348 155.075 1.00 3.20  ? 99  LEU A N   1 
ATOM 742  C CA  . LEU A 1 115 ? 174.587 145.604 155.830 1.00 3.20  ? 99  LEU A CA  1 
ATOM 743  C C   . LEU A 1 115 ? 174.840 145.516 157.330 1.00 3.20  ? 99  LEU A C   1 
ATOM 744  O O   . LEU A 1 115 ? 174.396 146.379 158.095 1.00 3.20  ? 99  LEU A O   1 
ATOM 745  C CB  . LEU A 1 115 ? 173.498 144.623 155.404 1.00 3.20  ? 99  LEU A CB  1 
ATOM 746  C CG  . LEU A 1 115 ? 172.081 145.183 155.342 1.00 3.20  ? 99  LEU A CG  1 
ATOM 747  C CD1 . LEU A 1 115 ? 172.067 146.478 154.559 1.00 3.20  ? 99  LEU A CD1 1 
ATOM 748  C CD2 . LEU A 1 115 ? 171.154 144.171 154.706 1.00 3.20  ? 99  LEU A CD2 1 
ATOM 749  N N   . VAL A 1 116 ? 175.556 144.478 157.771 1.00 9.84  ? 100 VAL A N   1 
ATOM 750  C CA  . VAL A 1 116 ? 175.859 144.342 159.191 1.00 9.84  ? 100 VAL A CA  1 
ATOM 751  C C   . VAL A 1 116 ? 176.842 145.405 159.656 1.00 9.84  ? 100 VAL A C   1 
ATOM 752  O O   . VAL A 1 116 ? 176.957 145.654 160.861 1.00 9.84  ? 100 VAL A O   1 
ATOM 753  C CB  . VAL A 1 116 ? 176.396 142.935 159.508 1.00 9.84  ? 100 VAL A CB  1 
ATOM 754  C CG1 . VAL A 1 116 ? 177.895 142.869 159.285 1.00 9.84  ? 100 VAL A CG1 1 
ATOM 755  C CG2 . VAL A 1 116 ? 176.059 142.561 160.933 1.00 9.84  ? 100 VAL A CG2 1 
ATOM 756  N N   . ASP A 1 117 ? 177.567 146.037 158.730 1.00 16.41 ? 101 ASP A N   1 
ATOM 757  C CA  . ASP A 1 117 ? 178.424 147.153 159.105 1.00 16.41 ? 101 ASP A CA  1 
ATOM 758  C C   . ASP A 1 117 ? 177.608 148.405 159.388 1.00 16.41 ? 101 ASP A C   1 
ATOM 759  O O   . ASP A 1 117 ? 177.998 149.221 160.229 1.00 16.41 ? 101 ASP A O   1 
ATOM 760  C CB  . ASP A 1 117 ? 179.449 147.420 158.004 1.00 16.41 ? 101 ASP A CB  1 
ATOM 761  C CG  . ASP A 1 117 ? 180.625 148.234 158.491 1.00 16.41 ? 101 ASP A CG  1 
ATOM 762  O OD1 . ASP A 1 117 ? 180.717 148.476 159.712 1.00 16.41 ? 101 ASP A OD1 1 
ATOM 763  O OD2 . ASP A 1 117 ? 181.462 148.629 157.652 1.00 16.41 ? 101 ASP A OD2 1 
ATOM 764  N N   . TYR A 1 118 ? 176.480 148.576 158.695 1.00 9.84  ? 102 TYR A N   1 
ATOM 765  C CA  . TYR A 1 118 ? 175.626 149.728 158.958 1.00 9.84  ? 102 TYR A CA  1 
ATOM 766  C C   . TYR A 1 118 ? 174.847 149.562 160.256 1.00 9.84  ? 102 TYR A C   1 
ATOM 767  O O   . TYR A 1 118 ? 174.699 150.521 161.021 1.00 9.84  ? 102 TYR A O   1 
ATOM 768  C CB  . TYR A 1 118 ? 174.661 149.954 157.797 1.00 9.84  ? 102 TYR A CB  1 
ATOM 769  C CG  . TYR A 1 118 ? 173.457 150.766 158.200 1.00 9.84  ? 102 TYR A CG  1 
ATOM 770  C CD1 . TYR A 1 118 ? 173.569 152.124 158.457 1.00 9.84  ? 102 TYR A CD1 1 
ATOM 771  C CD2 . TYR A 1 118 ? 172.212 150.174 158.345 1.00 9.84  ? 102 TYR A CD2 1 
ATOM 772  C CE1 . TYR A 1 118 ? 172.477 152.870 158.835 1.00 9.84  ? 102 TYR A CE1 1 
ATOM 773  C CE2 . TYR A 1 118 ? 171.113 150.912 158.723 1.00 9.84  ? 102 TYR A CE2 1 
ATOM 774  C CZ  . TYR A 1 118 ? 171.251 152.259 158.967 1.00 9.84  ? 102 TYR A CZ  1 
ATOM 775  O OH  . TYR A 1 118 ? 170.157 152.999 159.344 1.00 9.84  ? 102 TYR A OH  1 
ATOM 776  N N   . ILE A 1 119 ? 174.334 148.356 160.516 1.00 9.73  ? 103 ILE A N   1 
ATOM 777  C CA  . ILE A 1 119 ? 173.448 148.151 161.660 1.00 9.73  ? 103 ILE A CA  1 
ATOM 778  C C   . ILE A 1 119 ? 174.177 148.437 162.966 1.00 9.73  ? 103 ILE A C   1 
ATOM 779  O O   . ILE A 1 119 ? 173.637 149.093 163.865 1.00 9.73  ? 103 ILE A O   1 
ATOM 780  C CB  . ILE A 1 119 ? 172.867 146.725 161.638 1.00 9.73  ? 103 ILE A CB  1 
ATOM 781  C CG1 . ILE A 1 119 ? 172.037 146.504 160.374 1.00 9.73  ? 103 ILE A CG1 1 
ATOM 782  C CG2 . ILE A 1 119 ? 172.017 146.476 162.866 1.00 9.73  ? 103 ILE A CG2 1 
ATOM 783  C CD1 . ILE A 1 119 ? 171.356 145.157 160.323 1.00 9.73  ? 103 ILE A CD1 1 
ATOM 784  N N   . TYR A 1 120 ? 175.416 147.962 163.090 1.00 3.61  ? 104 TYR A N   1 
ATOM 785  C CA  . TYR A 1 120 ? 176.141 148.108 164.347 1.00 3.61  ? 104 TYR A CA  1 
ATOM 786  C C   . TYR A 1 120 ? 176.806 149.475 164.463 1.00 3.61  ? 104 TYR A C   1 
ATOM 787  O O   . TYR A 1 120 ? 176.559 150.212 165.423 1.00 3.61  ? 104 TYR A O   1 
ATOM 788  C CB  . TYR A 1 120 ? 177.175 146.990 164.483 1.00 3.61  ? 104 TYR A CB  1 
ATOM 789  C CG  . TYR A 1 120 ? 176.602 145.717 165.056 1.00 3.61  ? 104 TYR A CG  1 
ATOM 790  C CD1 . TYR A 1 120 ? 175.751 144.921 164.309 1.00 3.61  ? 104 TYR A CD1 1 
ATOM 791  C CD2 . TYR A 1 120 ? 176.914 145.313 166.344 1.00 3.61  ? 104 TYR A CD2 1 
ATOM 792  C CE1 . TYR A 1 120 ? 175.224 143.760 164.828 1.00 3.61  ? 104 TYR A CE1 1 
ATOM 793  C CE2 . TYR A 1 120 ? 176.392 144.152 166.871 1.00 3.61  ? 104 TYR A CE2 1 
ATOM 794  C CZ  . TYR A 1 120 ? 175.548 143.380 166.108 1.00 3.61  ? 104 TYR A CZ  1 
ATOM 795  O OH  . TYR A 1 120 ? 175.025 142.221 166.630 1.00 3.61  ? 104 TYR A OH  1 
ATOM 796  N N   . HIS A 1 121 ? 177.649 149.835 163.496 1.00 2.57  ? 105 HIS A N   1 
ATOM 797  C CA  . HIS A 1 121 ? 178.402 151.084 163.578 1.00 2.57  ? 105 HIS A CA  1 
ATOM 798  C C   . HIS A 1 121 ? 177.624 152.255 162.981 1.00 2.57  ? 105 HIS A C   1 
ATOM 799  O O   . HIS A 1 121 ? 177.324 153.228 163.678 1.00 2.57  ? 105 HIS A O   1 
ATOM 800  C CB  . HIS A 1 121 ? 179.757 150.926 162.881 1.00 2.57  ? 105 HIS A CB  1 
ATOM 801  C CG  . HIS A 1 121 ? 180.563 149.769 163.385 1.00 2.57  ? 105 HIS A CG  1 
ATOM 802  N ND1 . HIS A 1 121 ? 180.358 149.203 164.624 1.00 2.57  ? 105 HIS A ND1 1 
ATOM 803  C CD2 . HIS A 1 121 ? 181.574 149.072 162.815 1.00 2.57  ? 105 HIS A CD2 1 
ATOM 804  C CE1 . HIS A 1 121 ? 181.209 148.207 164.796 1.00 2.57  ? 105 HIS A CE1 1 
ATOM 805  N NE2 . HIS A 1 121 ? 181.957 148.106 163.713 1.00 2.57  ? 105 HIS A NE2 1 
ATOM 806  N N   . GLY A 1 122 ? 177.291 152.174 161.696 1.00 3.61  ? 106 GLY A N   1 
ATOM 807  C CA  . GLY A 1 122 ? 176.534 153.231 161.055 1.00 3.61  ? 106 GLY A CA  1 
ATOM 808  C C   . GLY A 1 122 ? 177.292 153.969 159.972 1.00 3.61  ? 106 GLY A C   1 
ATOM 809  O O   . GLY A 1 122 ? 176.905 155.073 159.581 1.00 3.61  ? 106 GLY A O   1 
ATOM 810  N N   . THR A 1 123 ? 178.377 153.373 159.479 1.00 3.36  ? 107 THR A N   1 
ATOM 811  C CA  . THR A 1 123 ? 179.198 153.960 158.420 1.00 3.36  ? 107 THR A CA  1 
ATOM 812  C C   . THR A 1 123 ? 179.492 152.879 157.380 1.00 3.36  ? 107 THR A C   1 
ATOM 813  O O   . THR A 1 123 ? 180.508 152.184 157.447 1.00 3.36  ? 107 THR A O   1 
ATOM 814  C CB  . THR A 1 123 ? 180.478 154.573 158.998 1.00 3.36  ? 107 THR A CB  1 
ATOM 815  O OG1 . THR A 1 123 ? 181.401 154.861 157.940 1.00 3.36  ? 107 THR A OG1 1 
ATOM 816  C CG2 . THR A 1 123 ? 181.126 153.648 160.027 1.00 3.36  ? 107 THR A CG2 1 
ATOM 817  N N   . VAL A 1 124 ? 178.598 152.748 156.404 1.00 2.81  ? 108 VAL A N   1 
ATOM 818  C CA  . VAL A 1 124 ? 178.712 151.737 155.360 1.00 2.81  ? 108 VAL A CA  1 
ATOM 819  C C   . VAL A 1 124 ? 179.244 152.398 154.097 1.00 2.81  ? 108 VAL A C   1 
ATOM 820  O O   . VAL A 1 124 ? 178.719 153.428 153.657 1.00 2.81  ? 108 VAL A O   1 
ATOM 821  C CB  . VAL A 1 124 ? 177.360 151.049 155.101 1.00 2.81  ? 108 VAL A CB  1 
ATOM 822  C CG1 . VAL A 1 124 ? 176.247 152.077 154.989 1.00 2.81  ? 108 VAL A CG1 1 
ATOM 823  C CG2 . VAL A 1 124 ? 177.428 150.192 153.851 1.00 2.81  ? 108 VAL A CG2 1 
ATOM 824  N N   . LYS A 1 125 ? 180.294 151.818 153.521 1.00 1.85  ? 109 LYS A N   1 
ATOM 825  C CA  . LYS A 1 125 ? 180.894 152.354 152.302 1.00 1.85  ? 109 LYS A CA  1 
ATOM 826  C C   . LYS A 1 125 ? 180.096 151.827 151.117 1.00 1.85  ? 109 LYS A C   1 
ATOM 827  O O   . LYS A 1 125 ? 180.121 150.632 150.813 1.00 1.85  ? 109 LYS A O   1 
ATOM 828  C CB  . LYS A 1 125 ? 182.367 151.970 152.215 1.00 1.85  ? 109 LYS A CB  1 
ATOM 829  C CG  . LYS A 1 125 ? 182.923 151.869 150.803 1.00 1.85  ? 109 LYS A CG  1 
ATOM 830  C CD  . LYS A 1 125 ? 184.427 151.654 150.818 1.00 1.85  ? 109 LYS A CD  1 
ATOM 831  C CE  . LYS A 1 125 ? 185.175 152.976 150.816 1.00 1.85  ? 109 LYS A CE  1 
ATOM 832  N NZ  . LYS A 1 125 ? 185.020 153.699 149.524 1.00 1.85  ? 109 LYS A NZ  1 
ATOM 833  N N   . LEU A 1 126 ? 179.366 152.719 150.453 1.00 0.57  ? 110 LEU A N   1 
ATOM 834  C CA  . LEU A 1 126 ? 178.498 152.329 149.349 1.00 0.57  ? 110 LEU A CA  1 
ATOM 835  C C   . LEU A 1 126 ? 179.298 152.300 148.054 1.00 0.57  ? 110 LEU A C   1 
ATOM 836  O O   . LEU A 1 126 ? 179.741 153.345 147.568 1.00 0.57  ? 110 LEU A O   1 
ATOM 837  C CB  . LEU A 1 126 ? 177.322 153.295 149.235 1.00 0.57  ? 110 LEU A CB  1 
ATOM 838  C CG  . LEU A 1 126 ? 176.324 153.267 150.390 1.00 0.57  ? 110 LEU A CG  1 
ATOM 839  C CD1 . LEU A 1 126 ? 175.379 154.444 150.299 1.00 0.57  ? 110 LEU A CD1 1 
ATOM 840  C CD2 . LEU A 1 126 ? 175.551 151.964 150.388 1.00 0.57  ? 110 LEU A CD2 1 
ATOM 841  N N   . ARG A 1 127 ? 179.475 151.110 147.493 1.00 1.00  ? 111 ARG A N   1 
ATOM 842  C CA  . ARG A 1 127 ? 180.228 150.954 146.257 1.00 1.00  ? 111 ARG A CA  1 
ATOM 843  C C   . ARG A 1 127 ? 179.347 151.344 145.072 1.00 1.00  ? 111 ARG A C   1 
ATOM 844  O O   . ARG A 1 127 ? 178.286 151.954 145.225 1.00 1.00  ? 111 ARG A O   1 
ATOM 845  C CB  . ARG A 1 127 ? 180.755 149.527 146.134 1.00 1.00  ? 111 ARG A CB  1 
ATOM 846  C CG  . ARG A 1 127 ? 181.989 149.245 146.972 1.00 1.00  ? 111 ARG A CG  1 
ATOM 847  C CD  . ARG A 1 127 ? 183.209 149.931 146.387 1.00 1.00  ? 111 ARG A CD  1 
ATOM 848  N NE  . ARG A 1 127 ? 183.361 149.650 144.964 1.00 1.00  ? 111 ARG A NE  1 
ATOM 849  C CZ  . ARG A 1 127 ? 184.284 150.200 144.187 1.00 1.00  ? 111 ARG A CZ  1 
ATOM 850  N NH1 . ARG A 1 127 ? 185.163 151.065 144.665 1.00 1.00  ? 111 ARG A NH1 1 
ATOM 851  N NH2 . ARG A 1 127 ? 184.324 149.876 142.898 1.00 1.00  ? 111 ARG A NH2 1 
ATOM 852  N N   . ALA A 1 128 ? 179.790 151.000 143.864 1.00 1.56  ? 112 ALA A N   1 
ATOM 853  C CA  . ALA A 1 128 ? 179.057 151.308 142.643 1.00 1.56  ? 112 ALA A CA  1 
ATOM 854  C C   . ALA A 1 128 ? 178.336 150.096 142.069 1.00 1.56  ? 112 ALA A C   1 
ATOM 855  O O   . ALA A 1 128 ? 177.136 150.164 141.789 1.00 1.56  ? 112 ALA A O   1 
ATOM 856  C CB  . ALA A 1 128 ? 180.010 151.881 141.592 1.00 1.56  ? 112 ALA A CB  1 
ATOM 857  N N   . GLU A 1 129 ? 179.052 148.986 141.880 1.00 2.06  ? 113 GLU A N   1 
ATOM 858  C CA  . GLU A 1 129 ? 178.435 147.802 141.292 1.00 2.06  ? 113 GLU A CA  1 
ATOM 859  C C   . GLU A 1 129 ? 177.453 147.148 142.257 1.00 2.06  ? 113 GLU A C   1 
ATOM 860  O O   . GLU A 1 129 ? 176.377 146.700 141.845 1.00 2.06  ? 113 GLU A O   1 
ATOM 861  C CB  . GLU A 1 129 ? 179.519 146.815 140.852 1.00 2.06  ? 113 GLU A CB  1 
ATOM 862  C CG  . GLU A 1 129 ? 180.353 146.236 141.986 1.00 2.06  ? 113 GLU A CG  1 
ATOM 863  C CD  . GLU A 1 129 ? 181.768 145.904 141.562 1.00 2.06  ? 113 GLU A CD  1 
ATOM 864  O OE1 . GLU A 1 129 ? 182.050 145.937 140.347 1.00 2.06  ? 113 GLU A OE1 1 
ATOM 865  O OE2 . GLU A 1 129 ? 182.598 145.609 142.447 1.00 2.06  ? 113 GLU A OE2 1 
ATOM 866  N N   . GLU A 1 130 ? 177.802 147.082 143.541 1.00 1.40  ? 114 GLU A N   1 
ATOM 867  C CA  . GLU A 1 130 ? 176.925 146.492 144.553 1.00 1.40  ? 114 GLU A CA  1 
ATOM 868  C C   . GLU A 1 130 ? 176.072 147.586 145.205 1.00 1.40  ? 114 GLU A C   1 
ATOM 869  O O   . GLU A 1 130 ? 175.933 147.699 146.423 1.00 1.40  ? 114 GLU A O   1 
ATOM 870  C CB  . GLU A 1 130 ? 177.755 145.679 145.546 1.00 1.40  ? 114 GLU A CB  1 
ATOM 871  C CG  . GLU A 1 130 ? 178.473 146.441 146.659 1.00 1.40  ? 114 GLU A CG  1 
ATOM 872  C CD  . GLU A 1 130 ? 179.849 145.877 146.956 1.00 1.40  ? 114 GLU A CD  1 
ATOM 873  O OE1 . GLU A 1 130 ? 180.322 145.018 146.183 1.00 1.40  ? 114 GLU A OE1 1 
ATOM 874  O OE2 . GLU A 1 130 ? 180.458 146.291 147.965 1.00 1.40  ? 114 GLU A OE2 1 
ATOM 875  N N   . LEU A 1 131 ? 175.433 148.373 144.344 1.00 1.10  ? 115 LEU A N   1 
ATOM 876  C CA  . LEU A 1 131 ? 174.512 149.410 144.789 1.00 1.10  ? 115 LEU A CA  1 
ATOM 877  C C   . LEU A 1 131 ? 173.053 149.052 144.566 1.00 1.10  ? 115 LEU A C   1 
ATOM 878  O O   . LEU A 1 131 ? 172.215 149.410 145.395 1.00 1.10  ? 115 LEU A O   1 
ATOM 879  C CB  . LEU A 1 131 ? 174.824 150.743 144.087 1.00 1.10  ? 115 LEU A CB  1 
ATOM 880  C CG  . LEU A 1 131 ? 174.168 152.028 144.605 1.00 1.10  ? 115 LEU A CG  1 
ATOM 881  C CD1 . LEU A 1 131 ? 172.791 152.250 144.016 1.00 1.10  ? 115 LEU A CD1 1 
ATOM 882  C CD2 . LEU A 1 131 ? 174.094 152.011 146.121 1.00 1.10  ? 115 LEU A CD2 1 
ATOM 883  N N   . GLN A 1 132 ? 172.724 148.358 143.478 1.00 1.87  ? 116 GLN A N   1 
ATOM 884  C CA  . GLN A 1 132 ? 171.374 147.843 143.302 1.00 1.87  ? 116 GLN A CA  1 
ATOM 885  C C   . GLN A 1 132 ? 171.089 146.647 144.197 1.00 1.87  ? 116 GLN A C   1 
ATOM 886  O O   . GLN A 1 132 ? 169.929 146.235 144.302 1.00 1.87  ? 116 GLN A O   1 
ATOM 887  C CB  . GLN A 1 132 ? 171.137 147.459 141.839 1.00 1.87  ? 116 GLN A CB  1 
ATOM 888  C CG  . GLN A 1 132 ? 171.283 148.614 140.863 1.00 1.87  ? 116 GLN A CG  1 
ATOM 889  C CD  . GLN A 1 132 ? 170.424 148.443 139.626 1.00 1.87  ? 116 GLN A CD  1 
ATOM 890  O OE1 . GLN A 1 132 ? 169.388 147.780 139.663 1.00 1.87  ? 116 GLN A OE1 1 
ATOM 891  N NE2 . GLN A 1 132 ? 170.851 149.042 138.522 1.00 1.87  ? 116 GLN A NE2 1 
ATOM 892  N N   . GLU A 1 133 ? 172.113 146.083 144.838 1.00 2.93  ? 117 GLU A N   1 
ATOM 893  C CA  . GLU A 1 133 ? 171.932 144.978 145.767 1.00 2.93  ? 117 GLU A CA  1 
ATOM 894  C C   . GLU A 1 133 ? 171.701 145.434 147.201 1.00 2.93  ? 117 GLU A C   1 
ATOM 895  O O   . GLU A 1 133 ? 171.122 144.676 147.985 1.00 2.93  ? 117 GLU A O   1 
ATOM 896  C CB  . GLU A 1 133 ? 173.143 144.039 145.721 1.00 2.93  ? 117 GLU A CB  1 
ATOM 897  C CG  . GLU A 1 133 ? 172.904 142.682 146.359 1.00 2.93  ? 117 GLU A CG  1 
ATOM 898  C CD  . GLU A 1 133 ? 171.795 141.907 145.681 1.00 2.93  ? 117 GLU A CD  1 
ATOM 899  O OE1 . GLU A 1 133 ? 171.645 142.034 144.449 1.00 2.93  ? 117 GLU A OE1 1 
ATOM 900  O OE2 . GLU A 1 133 ? 171.071 141.169 146.382 1.00 2.93  ? 117 GLU A OE2 1 
ATOM 901  N N   . ILE A 1 134 ? 172.130 146.644 147.562 1.00 2.61  ? 118 ILE A N   1 
ATOM 902  C CA  . ILE A 1 134 ? 171.781 147.230 148.850 1.00 2.61  ? 118 ILE A CA  1 
ATOM 903  C C   . ILE A 1 134 ? 170.539 148.110 148.738 1.00 2.61  ? 118 ILE A C   1 
ATOM 904  O O   . ILE A 1 134 ? 170.271 148.927 149.622 1.00 2.61  ? 118 ILE A O   1 
ATOM 905  C CB  . ILE A 1 134 ? 172.962 148.009 149.453 1.00 2.61  ? 118 ILE A CB  1 
ATOM 906  C CG1 . ILE A 1 134 ? 174.274 147.273 149.204 1.00 2.61  ? 118 ILE A CG1 1 
ATOM 907  C CG2 . ILE A 1 134 ? 172.816 148.143 150.958 1.00 2.61  ? 118 ILE A CG2 1 
ATOM 908  C CD1 . ILE A 1 134 ? 175.493 148.116 149.502 1.00 2.61  ? 118 ILE A CD1 1 
ATOM 909  N N   . TYR A 1 135 ? 169.784 147.972 147.653 1.00 9.84  ? 119 TYR A N   1 
ATOM 910  C CA  . TYR A 1 135 ? 168.482 148.607 147.504 1.00 9.84  ? 119 TYR A CA  1 
ATOM 911  C C   . TYR A 1 135 ? 167.335 147.617 147.591 1.00 9.84  ? 119 TYR A C   1 
ATOM 912  O O   . TYR A 1 135 ? 166.308 147.923 148.198 1.00 9.84  ? 119 TYR A O   1 
ATOM 913  C CB  . TYR A 1 135 ? 168.404 149.352 146.167 1.00 9.84  ? 119 TYR A CB  1 
ATOM 914  C CG  . TYR A 1 135 ? 167.181 150.227 146.023 1.00 9.84  ? 119 TYR A CG  1 
ATOM 915  C CD1 . TYR A 1 135 ? 167.192 151.543 146.460 1.00 9.84  ? 119 TYR A CD1 1 
ATOM 916  C CD2 . TYR A 1 135 ? 166.019 149.741 145.444 1.00 9.84  ? 119 TYR A CD2 1 
ATOM 917  C CE1 . TYR A 1 135 ? 166.078 152.346 146.329 1.00 9.84  ? 119 TYR A CE1 1 
ATOM 918  C CE2 . TYR A 1 135 ? 164.901 150.536 145.311 1.00 9.84  ? 119 TYR A CE2 1 
ATOM 919  C CZ  . TYR A 1 135 ? 164.937 151.838 145.754 1.00 9.84  ? 119 TYR A CZ  1 
ATOM 920  O OH  . TYR A 1 135 ? 163.825 152.636 145.624 1.00 9.84  ? 119 TYR A OH  1 
ATOM 921  N N   . GLU A 1 136 ? 167.484 146.434 146.995 1.00 10.03 ? 120 GLU A N   1 
ATOM 922  C CA  . GLU A 1 136 ? 166.436 145.425 147.072 1.00 10.03 ? 120 GLU A CA  1 
ATOM 923  C C   . GLU A 1 136 ? 166.391 144.759 148.443 1.00 10.03 ? 120 GLU A C   1 
ATOM 924  O O   . GLU A 1 136 ? 165.304 144.516 148.978 1.00 10.03 ? 120 GLU A O   1 
ATOM 925  C CB  . GLU A 1 136 ? 166.634 144.381 145.974 1.00 10.03 ? 120 GLU A CB  1 
ATOM 926  C CG  . GLU A 1 136 ? 166.515 144.944 144.568 1.00 10.03 ? 120 GLU A CG  1 
ATOM 927  C CD  . GLU A 1 136 ? 166.916 143.944 143.503 1.00 10.03 ? 120 GLU A CD  1 
ATOM 928  O OE1 . GLU A 1 136 ? 167.910 143.218 143.711 1.00 10.03 ? 120 GLU A OE1 1 
ATOM 929  O OE2 . GLU A 1 136 ? 166.239 143.887 142.456 1.00 10.03 ? 120 GLU A OE2 1 
ATOM 930  N N   . VAL A 1 137 ? 167.551 144.456 149.029 1.00 7.43  ? 121 VAL A N   1 
ATOM 931  C CA  . VAL A 1 137 ? 167.546 143.779 150.323 1.00 7.43  ? 121 VAL A CA  1 
ATOM 932  C C   . VAL A 1 137 ? 167.360 144.774 151.461 1.00 7.43  ? 121 VAL A C   1 
ATOM 933  O O   . VAL A 1 137 ? 166.921 144.394 152.552 1.00 7.43  ? 121 VAL A O   1 
ATOM 934  C CB  . VAL A 1 137 ? 168.826 142.950 150.521 1.00 7.43  ? 121 VAL A CB  1 
ATOM 935  C CG1 . VAL A 1 137 ? 169.068 142.047 149.323 1.00 7.43  ? 121 VAL A CG1 1 
ATOM 936  C CG2 . VAL A 1 137 ? 170.018 143.848 150.795 1.00 7.43  ? 121 VAL A CG2 1 
ATOM 937  N N   . SER A 1 138 ? 167.687 146.048 151.244 1.00 5.92  ? 122 SER A N   1 
ATOM 938  C CA  . SER A 1 138 ? 167.470 147.049 152.279 1.00 5.92  ? 122 SER A CA  1 
ATOM 939  C C   . SER A 1 138 ? 166.008 147.443 152.413 1.00 5.92  ? 122 SER A C   1 
ATOM 940  O O   . SER A 1 138 ? 165.649 148.094 153.398 1.00 5.92  ? 122 SER A O   1 
ATOM 941  C CB  . SER A 1 138 ? 168.309 148.294 152.002 1.00 5.92  ? 122 SER A CB  1 
ATOM 942  O OG  . SER A 1 138 ? 168.114 149.266 153.011 1.00 5.92  ? 122 SER A OG  1 
ATOM 943  N N   . ASP A 1 139 ? 165.166 147.074 151.451 1.00 9.84  ? 123 ASP A N   1 
ATOM 944  C CA  . ASP A 1 139 ? 163.736 147.332 151.534 1.00 9.84  ? 123 ASP A CA  1 
ATOM 945  C C   . ASP A 1 139 ? 162.965 146.199 152.191 1.00 9.84  ? 123 ASP A C   1 
ATOM 946  O O   . ASP A 1 139 ? 161.997 146.462 152.912 1.00 9.84  ? 123 ASP A O   1 
ATOM 947  C CB  . ASP A 1 139 ? 163.159 147.586 150.138 1.00 9.84  ? 123 ASP A CB  1 
ATOM 948  C CG  . ASP A 1 139 ? 161.647 147.609 150.130 1.00 9.84  ? 123 ASP A CG  1 
ATOM 949  O OD1 . ASP A 1 139 ? 161.060 148.388 150.909 1.00 9.84  ? 123 ASP A OD1 1 
ATOM 950  O OD2 . ASP A 1 139 ? 161.045 146.845 149.347 1.00 9.84  ? 123 ASP A OD2 1 
ATOM 951  N N   . MET A 1 140 ? 163.368 144.948 151.961 1.00 13.98 ? 124 MET A N   1 
ATOM 952  C CA  . MET A 1 140 ? 162.701 143.829 152.617 1.00 13.98 ? 124 MET A CA  1 
ATOM 953  C C   . MET A 1 140 ? 162.954 143.843 154.119 1.00 13.98 ? 124 MET A C   1 
ATOM 954  O O   . MET A 1 140 ? 162.054 143.535 154.908 1.00 13.98 ? 124 MET A O   1 
ATOM 955  C CB  . MET A 1 140 ? 163.163 142.508 152.008 1.00 13.98 ? 124 MET A CB  1 
ATOM 956  C CG  . MET A 1 140 ? 162.288 141.325 152.381 1.00 13.98 ? 124 MET A CG  1 
ATOM 957  S SD  . MET A 1 140 ? 162.920 139.749 151.775 1.00 13.98 ? 124 MET A SD  1 
ATOM 958  C CE  . MET A 1 140 ? 164.319 140.294 150.802 1.00 13.98 ? 124 MET A CE  1 
ATOM 959  N N   . TYR A 1 141 ? 164.171 144.197 154.533 1.00 6.05  ? 125 TYR A N   1 
ATOM 960  C CA  . TYR A 1 141 ? 164.475 144.340 155.949 1.00 6.05  ? 125 TYR A CA  1 
ATOM 961  C C   . TYR A 1 141 ? 163.898 145.617 156.542 1.00 6.05  ? 125 TYR A C   1 
ATOM 962  O O   . TYR A 1 141 ? 163.940 145.788 157.764 1.00 6.05  ? 125 TYR A O   1 
ATOM 963  C CB  . TYR A 1 141 ? 165.989 144.298 156.171 1.00 6.05  ? 125 TYR A CB  1 
ATOM 964  C CG  . TYR A 1 141 ? 166.627 142.978 155.796 1.00 6.05  ? 125 TYR A CG  1 
ATOM 965  C CD1 . TYR A 1 141 ? 165.860 141.833 155.641 1.00 6.05  ? 125 TYR A CD1 1 
ATOM 966  C CD2 . TYR A 1 141 ? 167.996 142.877 155.597 1.00 6.05  ? 125 TYR A CD2 1 
ATOM 967  C CE1 . TYR A 1 141 ? 166.435 140.627 155.298 1.00 6.05  ? 125 TYR A CE1 1 
ATOM 968  C CE2 . TYR A 1 141 ? 168.580 141.673 155.253 1.00 6.05  ? 125 TYR A CE2 1 
ATOM 969  C CZ  . TYR A 1 141 ? 167.793 140.553 155.105 1.00 6.05  ? 125 TYR A CZ  1 
ATOM 970  O OH  . TYR A 1 141 ? 168.364 139.350 154.764 1.00 6.05  ? 125 TYR A OH  1 
ATOM 971  N N   . GLN A 1 142 ? 163.367 146.508 155.703 1.00 7.30  ? 126 GLN A N   1 
ATOM 972  C CA  . GLN A 1 142 ? 162.679 147.723 156.144 1.00 7.30  ? 126 GLN A CA  1 
ATOM 973  C C   . GLN A 1 142 ? 163.588 148.624 156.976 1.00 7.30  ? 126 GLN A C   1 
ATOM 974  O O   . GLN A 1 142 ? 163.181 149.169 158.004 1.00 7.30  ? 126 GLN A O   1 
ATOM 975  C CB  . GLN A 1 142 ? 161.396 147.384 156.906 1.00 7.30  ? 126 GLN A CB  1 
ATOM 976  C CG  . GLN A 1 142 ? 160.352 146.694 156.045 1.00 7.30  ? 126 GLN A CG  1 
ATOM 977  C CD  . GLN A 1 142 ? 159.053 146.447 156.781 1.00 7.30  ? 126 GLN A CD  1 
ATOM 978  O OE1 . GLN A 1 142 ? 158.672 147.215 157.663 1.00 7.30  ? 126 GLN A OE1 1 
ATOM 979  N NE2 . GLN A 1 142 ? 158.366 145.369 156.423 1.00 7.30  ? 126 GLN A NE2 1 
ATOM 980  N N   . LEU A 1 143 ? 164.832 148.779 156.531 1.00 3.40  ? 127 LEU A N   1 
ATOM 981  C CA  . LEU A 1 143 ? 165.728 149.789 157.086 1.00 3.40  ? 127 LEU A CA  1 
ATOM 982  C C   . LEU A 1 143 ? 165.399 151.120 156.425 1.00 3.40  ? 127 LEU A C   1 
ATOM 983  O O   . LEU A 1 143 ? 165.845 151.402 155.312 1.00 3.40  ? 127 LEU A O   1 
ATOM 984  C CB  . LEU A 1 143 ? 167.185 149.404 156.855 1.00 3.40  ? 127 LEU A CB  1 
ATOM 985  C CG  . LEU A 1 143 ? 167.713 148.135 157.524 1.00 3.40  ? 127 LEU A CG  1 
ATOM 986  C CD1 . LEU A 1 143 ? 168.842 147.540 156.708 1.00 3.40  ? 127 LEU A CD1 1 
ATOM 987  C CD2 . LEU A 1 143 ? 168.185 148.435 158.930 1.00 3.40  ? 127 LEU A CD2 1 
ATOM 988  N N   . THR A 1 144 ? 164.613 151.952 157.107 1.00 3.84  ? 128 THR A N   1 
ATOM 989  C CA  . THR A 1 144 ? 164.112 153.191 156.525 1.00 3.84  ? 128 THR A CA  1 
ATOM 990  C C   . THR A 1 144 ? 165.143 154.313 156.517 1.00 3.84  ? 128 THR A C   1 
ATOM 991  O O   . THR A 1 144 ? 164.770 155.472 156.300 1.00 3.84  ? 128 THR A O   1 
ATOM 992  C CB  . THR A 1 144 ? 162.854 153.653 157.264 1.00 3.84  ? 128 THR A CB  1 
ATOM 993  O OG1 . THR A 1 144 ? 162.973 153.347 158.659 1.00 3.84  ? 128 THR A OG1 1 
ATOM 994  C CG2 . THR A 1 144 ? 161.621 152.964 156.697 1.00 3.84  ? 128 THR A CG2 1 
ATOM 995  N N   . SER A 1 145 ? 166.416 154.010 156.748 1.00 7.51  ? 129 SER A N   1 
ATOM 996  C CA  . SER A 1 145 ? 167.475 155.008 156.664 1.00 7.51  ? 129 SER A CA  1 
ATOM 997  C C   . SER A 1 145 ? 168.487 154.709 155.573 1.00 7.51  ? 129 SER A C   1 
ATOM 998  O O   . SER A 1 145 ? 168.953 155.633 154.903 1.00 7.51  ? 129 SER A O   1 
ATOM 999  C CB  . SER A 1 145 ? 168.198 155.133 158.009 1.00 7.51  ? 129 SER A CB  1 
ATOM 1000 O OG  . SER A 1 145 ? 169.132 156.198 157.980 1.00 7.51  ? 129 SER A OG  1 
ATOM 1001 N N   . LEU A 1 146 ? 168.850 153.440 155.380 1.00 9.84  ? 130 LEU A N   1 
ATOM 1002 C CA  . LEU A 1 146 ? 169.688 153.076 154.245 1.00 9.84  ? 130 LEU A CA  1 
ATOM 1003 C C   . LEU A 1 146 ? 168.899 153.053 152.945 1.00 9.84  ? 130 LEU A C   1 
ATOM 1004 O O   . LEU A 1 146 ? 169.440 153.401 151.889 1.00 9.84  ? 130 LEU A O   1 
ATOM 1005 C CB  . LEU A 1 146 ? 170.340 151.715 154.481 1.00 9.84  ? 130 LEU A CB  1 
ATOM 1006 C CG  . LEU A 1 146 ? 171.598 151.427 153.664 1.00 9.84  ? 130 LEU A CG  1 
ATOM 1007 C CD1 . LEU A 1 146 ? 172.616 152.531 153.851 1.00 9.84  ? 130 LEU A CD1 1 
ATOM 1008 C CD2 . LEU A 1 146 ? 172.188 150.089 154.054 1.00 9.84  ? 130 LEU A CD2 1 
ATOM 1009 N N   . PHE A 1 147 ? 167.629 152.648 152.999 1.00 7.09  ? 131 PHE A N   1 
ATOM 1010 C CA  . PHE A 1 147 ? 166.801 152.639 151.799 1.00 7.09  ? 131 PHE A CA  1 
ATOM 1011 C C   . PHE A 1 147 ? 166.501 154.051 151.314 1.00 7.09  ? 131 PHE A C   1 
ATOM 1012 O O   . PHE A 1 147 ? 166.286 154.259 150.116 1.00 7.09  ? 131 PHE A O   1 
ATOM 1013 C CB  . PHE A 1 147 ? 165.505 151.876 152.065 1.00 7.09  ? 131 PHE A CB  1 
ATOM 1014 C CG  . PHE A 1 147 ? 164.496 151.990 150.964 1.00 7.09  ? 131 PHE A CG  1 
ATOM 1015 C CD1 . PHE A 1 147 ? 164.638 151.258 149.801 1.00 7.09  ? 131 PHE A CD1 1 
ATOM 1016 C CD2 . PHE A 1 147 ? 163.399 152.822 151.096 1.00 7.09  ? 131 PHE A CD2 1 
ATOM 1017 C CE1 . PHE A 1 147 ? 163.710 151.358 148.787 1.00 7.09  ? 131 PHE A CE1 1 
ATOM 1018 C CE2 . PHE A 1 147 ? 162.467 152.927 150.086 1.00 7.09  ? 131 PHE A CE2 1 
ATOM 1019 C CZ  . PHE A 1 147 ? 162.623 152.194 148.930 1.00 7.09  ? 131 PHE A CZ  1 
ATOM 1020 N N   . GLU A 1 148 ? 166.486 155.028 152.218 1.00 2.66  ? 132 GLU A N   1 
ATOM 1021 C CA  . GLU A 1 148 ? 166.300 156.419 151.830 1.00 2.66  ? 132 GLU A CA  1 
ATOM 1022 C C   . GLU A 1 148 ? 167.603 157.094 151.431 1.00 2.66  ? 132 GLU A C   1 
ATOM 1023 O O   . GLU A 1 148 ? 167.587 158.280 151.085 1.00 2.66  ? 132 GLU A O   1 
ATOM 1024 C CB  . GLU A 1 148 ? 165.637 157.204 152.964 1.00 2.66  ? 132 GLU A CB  1 
ATOM 1025 C CG  . GLU A 1 148 ? 164.134 157.357 152.808 1.00 2.66  ? 132 GLU A CG  1 
ATOM 1026 C CD  . GLU A 1 148 ? 163.419 157.479 154.138 1.00 2.66  ? 132 GLU A CD  1 
ATOM 1027 O OE1 . GLU A 1 148 ? 163.753 158.401 154.911 1.00 2.66  ? 132 GLU A OE1 1 
ATOM 1028 O OE2 . GLU A 1 148 ? 162.523 156.653 154.410 1.00 2.66  ? 132 GLU A OE2 1 
ATOM 1029 N N   . GLU A 1 149 ? 168.722 156.379 151.481 1.00 1.22  ? 133 GLU A N   1 
ATOM 1030 C CA  . GLU A 1 149 ? 169.997 156.871 150.978 1.00 1.22  ? 133 GLU A CA  1 
ATOM 1031 C C   . GLU A 1 149 ? 170.441 156.160 149.713 1.00 1.22  ? 133 GLU A C   1 
ATOM 1032 O O   . GLU A 1 149 ? 171.021 156.792 148.827 1.00 1.22  ? 133 GLU A O   1 
ATOM 1033 C CB  . GLU A 1 149 ? 171.085 156.733 152.051 1.00 1.22  ? 133 GLU A CB  1 
ATOM 1034 C CG  . GLU A 1 149 ? 172.039 157.911 152.112 1.00 1.22  ? 133 GLU A CG  1 
ATOM 1035 C CD  . GLU A 1 149 ? 172.939 157.994 150.897 1.00 1.22  ? 133 GLU A CD  1 
ATOM 1036 O OE1 . GLU A 1 149 ? 173.337 156.930 150.381 1.00 1.22  ? 133 GLU A OE1 1 
ATOM 1037 O OE2 . GLU A 1 149 ? 173.248 159.121 150.457 1.00 1.22  ? 133 GLU A OE2 1 
ATOM 1038 N N   . CYS A 1 150 ? 170.181 154.856 149.598 1.00 0.41  ? 134 CYS A N   1 
ATOM 1039 C CA  . CYS A 1 150 ? 170.390 154.175 148.328 1.00 0.41  ? 134 CYS A CA  1 
ATOM 1040 C C   . CYS A 1 150 ? 169.396 154.634 147.271 1.00 0.41  ? 134 CYS A C   1 
ATOM 1041 O O   . CYS A 1 150 ? 169.659 154.470 146.076 1.00 0.41  ? 134 CYS A O   1 
ATOM 1042 C CB  . CYS A 1 150 ? 170.297 152.662 148.514 1.00 0.41  ? 134 CYS A CB  1 
ATOM 1043 S SG  . CYS A 1 150 ? 171.780 151.913 149.214 1.00 0.41  ? 134 CYS A SG  1 
ATOM 1044 N N   . SER A 1 151 ? 168.259 155.197 147.685 1.00 2.63  ? 135 SER A N   1 
ATOM 1045 C CA  . SER A 1 151 ? 167.339 155.795 146.725 1.00 2.63  ? 135 SER A CA  1 
ATOM 1046 C C   . SER A 1 151 ? 167.907 157.087 146.154 1.00 2.63  ? 135 SER A C   1 
ATOM 1047 O O   . SER A 1 151 ? 167.791 157.345 144.951 1.00 2.63  ? 135 SER A O   1 
ATOM 1048 C CB  . SER A 1 151 ? 165.985 156.052 147.383 1.00 2.63  ? 135 SER A CB  1 
ATOM 1049 O OG  . SER A 1 151 ? 165.183 156.896 146.579 1.00 2.63  ? 135 SER A OG  1 
ATOM 1050 N N   . ARG A 1 152 ? 168.522 157.914 147.003 1.00 0.00  ? 136 ARG A N   1 
ATOM 1051 C CA  . ARG A 1 152 ? 169.151 159.134 146.511 1.00 0.00  ? 136 ARG A CA  1 
ATOM 1052 C C   . ARG A 1 152 ? 170.379 158.828 145.668 1.00 0.00  ? 136 ARG A C   1 
ATOM 1053 O O   . ARG A 1 152 ? 170.716 159.601 144.765 1.00 0.00  ? 136 ARG A O   1 
ATOM 1054 C CB  . ARG A 1 152 ? 169.522 160.048 147.678 1.00 0.00  ? 136 ARG A CB  1 
ATOM 1055 C CG  . ARG A 1 152 ? 168.452 161.067 148.023 1.00 0.00  ? 136 ARG A CG  1 
ATOM 1056 C CD  . ARG A 1 152 ? 167.952 161.767 146.769 1.00 0.00  ? 136 ARG A CD  1 
ATOM 1057 N NE  . ARG A 1 152 ? 166.959 162.793 147.066 1.00 0.00  ? 136 ARG A NE  1 
ATOM 1058 C CZ  . ARG A 1 152 ? 166.375 163.555 146.151 1.00 0.00  ? 136 ARG A CZ  1 
ATOM 1059 N NH1 . ARG A 1 152 ? 166.659 163.431 144.864 1.00 0.00  ? 136 ARG A NH1 1 
ATOM 1060 N NH2 . ARG A 1 152 ? 165.486 164.465 146.537 1.00 0.00  ? 136 ARG A NH2 1 
ATOM 1061 N N   . PHE A 1 153 ? 171.064 157.719 145.951 1.00 0.53  ? 137 PHE A N   1 
ATOM 1062 C CA  . PHE A 1 153 ? 172.194 157.319 145.120 1.00 0.53  ? 137 PHE A CA  1 
ATOM 1063 C C   . PHE A 1 153 ? 171.743 156.996 143.702 1.00 0.53  ? 137 PHE A C   1 
ATOM 1064 O O   . PHE A 1 153 ? 172.402 157.384 142.731 1.00 0.53  ? 137 PHE A O   1 
ATOM 1065 C CB  . PHE A 1 153 ? 172.906 156.122 145.749 1.00 0.53  ? 137 PHE A CB  1 
ATOM 1066 C CG  . PHE A 1 153 ? 174.340 155.977 145.331 1.00 0.53  ? 137 PHE A CG  1 
ATOM 1067 C CD1 . PHE A 1 153 ? 174.669 155.637 144.033 1.00 0.53  ? 137 PHE A CD1 1 
ATOM 1068 C CD2 . PHE A 1 153 ? 175.359 156.180 146.241 1.00 0.53  ? 137 PHE A CD2 1 
ATOM 1069 C CE1 . PHE A 1 153 ? 175.985 155.503 143.652 1.00 0.53  ? 137 PHE A CE1 1 
ATOM 1070 C CE2 . PHE A 1 153 ? 176.676 156.047 145.865 1.00 0.53  ? 137 PHE A CE2 1 
ATOM 1071 C CZ  . PHE A 1 153 ? 176.989 155.709 144.569 1.00 0.53  ? 137 PHE A CZ  1 
ATOM 1072 N N   . LEU A 1 154 ? 170.621 156.289 143.561 1.00 0.13  ? 138 LEU A N   1 
ATOM 1073 C CA  . LEU A 1 154 ? 170.095 155.967 142.241 1.00 0.13  ? 138 LEU A CA  1 
ATOM 1074 C C   . LEU A 1 154 ? 169.386 157.141 141.582 1.00 0.13  ? 138 LEU A C   1 
ATOM 1075 O O   . LEU A 1 154 ? 169.037 157.043 140.402 1.00 0.13  ? 138 LEU A O   1 
ATOM 1076 C CB  . LEU A 1 154 ? 169.141 154.776 142.328 1.00 0.13  ? 138 LEU A CB  1 
ATOM 1077 C CG  . LEU A 1 154 ? 169.806 153.407 142.442 1.00 0.13  ? 138 LEU A CG  1 
ATOM 1078 C CD1 . LEU A 1 154 ? 168.766 152.315 142.595 1.00 0.13  ? 138 LEU A CD1 1 
ATOM 1079 C CD2 . LEU A 1 154 ? 170.672 153.154 141.224 1.00 0.13  ? 138 LEU A CD2 1 
ATOM 1080 N N   . ALA A 1 155 ? 169.155 158.234 142.302 1.00 9.84  ? 139 ALA A N   1 
ATOM 1081 C CA  . ALA A 1 155 ? 168.533 159.408 141.709 1.00 9.84  ? 139 ALA A CA  1 
ATOM 1082 C C   . ALA A 1 155 ? 169.540 160.351 141.068 1.00 9.84  ? 139 ALA A C   1 
ATOM 1083 O O   . ALA A 1 155 ? 169.133 161.367 140.495 1.00 9.84  ? 139 ALA A O   1 
ATOM 1084 C CB  . ALA A 1 155 ? 167.719 160.164 142.761 1.00 9.84  ? 139 ALA A CB  1 
ATOM 1085 N N   . ARG A 1 156 ? 170.838 160.048 141.150 1.00 0.45  ? 140 ARG A N   1 
ATOM 1086 C CA  . ARG A 1 156 ? 171.868 160.894 140.569 1.00 0.45  ? 140 ARG A CA  1 
ATOM 1087 C C   . ARG A 1 156 ? 172.863 160.149 139.693 1.00 0.45  ? 140 ARG A C   1 
ATOM 1088 O O   . ARG A 1 156 ? 173.657 160.801 139.008 1.00 0.45  ? 140 ARG A O   1 
ATOM 1089 C CB  . ARG A 1 156 ? 172.645 161.634 141.669 1.00 0.45  ? 140 ARG A CB  1 
ATOM 1090 C CG  . ARG A 1 156 ? 173.670 160.780 142.384 1.00 0.45  ? 140 ARG A CG  1 
ATOM 1091 C CD  . ARG A 1 156 ? 174.739 161.643 143.025 1.00 0.45  ? 140 ARG A CD  1 
ATOM 1092 N NE  . ARG A 1 156 ? 174.293 162.212 144.290 1.00 0.45  ? 140 ARG A NE  1 
ATOM 1093 C CZ  . ARG A 1 156 ? 174.452 161.628 145.468 1.00 0.45  ? 140 ARG A CZ  1 
ATOM 1094 N NH1 . ARG A 1 156 ? 175.053 160.456 145.582 1.00 0.45  ? 140 ARG A NH1 1 
ATOM 1095 N NH2 . ARG A 1 156 ? 174.000 162.236 146.560 1.00 0.45  ? 140 ARG A NH2 1 
ATOM 1096 N N   . THR A 1 157 ? 172.849 158.817 139.692 1.00 0.47  ? 141 THR A N   1 
ATOM 1097 C CA  . THR A 1 157 ? 173.712 158.027 138.826 1.00 0.47  ? 141 THR A CA  1 
ATOM 1098 C C   . THR A 1 157 ? 172.995 157.553 137.567 1.00 0.47  ? 141 THR A C   1 
ATOM 1099 O O   . THR A 1 157 ? 173.527 156.704 136.842 1.00 0.47  ? 141 THR A O   1 
ATOM 1100 C CB  . THR A 1 157 ? 174.277 156.829 139.592 1.00 0.47  ? 141 THR A CB  1 
ATOM 1101 O OG1 . THR A 1 157 ? 175.253 156.161 138.784 1.00 0.47  ? 141 THR A OG1 1 
ATOM 1102 C CG2 . THR A 1 157 ? 173.169 155.852 139.944 1.00 0.47  ? 141 THR A CG2 1 
ATOM 1103 N N   . VAL A 1 158 ? 171.810 158.086 137.293 1.00 1.51  ? 142 VAL A N   1 
ATOM 1104 C CA  . VAL A 1 158 ? 171.000 157.676 136.151 1.00 1.51  ? 142 VAL A CA  1 
ATOM 1105 C C   . VAL A 1 158 ? 171.551 158.310 134.881 1.00 1.51  ? 142 VAL A C   1 
ATOM 1106 O O   . VAL A 1 158 ? 171.765 159.526 134.822 1.00 1.51  ? 142 VAL A O   1 
ATOM 1107 C CB  . VAL A 1 158 ? 169.528 158.062 136.364 1.00 1.51  ? 142 VAL A CB  1 
ATOM 1108 C CG1 . VAL A 1 158 ? 168.801 158.106 135.044 1.00 1.51  ? 142 VAL A CG1 1 
ATOM 1109 C CG2 . VAL A 1 158 ? 168.859 157.069 137.285 1.00 1.51  ? 142 VAL A CG2 1 
ATOM 1110 N N   . GLN A 1 159 ? 171.775 157.485 133.862 1.00 2.56  ? 143 GLN A N   1 
ATOM 1111 C CA  . GLN A 1 159 ? 172.202 157.937 132.548 1.00 2.56  ? 143 GLN A CA  1 
ATOM 1112 C C   . GLN A 1 159 ? 171.146 157.566 131.513 1.00 2.56  ? 143 GLN A C   1 
ATOM 1113 O O   . GLN A 1 159 ? 170.131 156.938 131.824 1.00 2.56  ? 143 GLN A O   1 
ATOM 1114 C CB  . GLN A 1 159 ? 173.561 157.335 132.169 1.00 2.56  ? 143 GLN A CB  1 
ATOM 1115 C CG  . GLN A 1 159 ? 174.593 157.394 133.281 1.00 2.56  ? 143 GLN A CG  1 
ATOM 1116 C CD  . GLN A 1 159 ? 175.318 156.077 133.472 1.00 2.56  ? 143 GLN A CD  1 
ATOM 1117 O OE1 . GLN A 1 159 ? 175.168 155.152 132.675 1.00 2.56  ? 143 GLN A OE1 1 
ATOM 1118 N NE2 . GLN A 1 159 ? 176.111 155.986 134.533 1.00 2.56  ? 143 GLN A NE2 1 
ATOM 1119 N N   . VAL A 1 160 ? 171.404 157.958 130.263 1.00 2.89  ? 144 VAL A N   1 
ATOM 1120 C CA  . VAL A 1 160 ? 170.423 157.765 129.197 1.00 2.89  ? 144 VAL A CA  1 
ATOM 1121 C C   . VAL A 1 160 ? 170.183 156.287 128.917 1.00 2.89  ? 144 VAL A C   1 
ATOM 1122 O O   . VAL A 1 160 ? 169.083 155.897 128.507 1.00 2.89  ? 144 VAL A O   1 
ATOM 1123 C CB  . VAL A 1 160 ? 170.860 158.526 127.928 1.00 2.89  ? 144 VAL A CB  1 
ATOM 1124 C CG1 . VAL A 1 160 ? 171.820 157.698 127.087 1.00 2.89  ? 144 VAL A CG1 1 
ATOM 1125 C CG2 . VAL A 1 160 ? 169.648 158.901 127.106 1.00 2.89  ? 144 VAL A CG2 1 
ATOM 1126 N N   . GLY A 1 161 ? 171.196 155.441 129.123 1.00 2.47  ? 145 GLY A N   1 
ATOM 1127 C CA  . GLY A 1 161 ? 171.036 154.021 128.865 1.00 2.47  ? 145 GLY A CA  1 
ATOM 1128 C C   . GLY A 1 161 ? 170.525 153.220 130.039 1.00 2.47  ? 145 GLY A C   1 
ATOM 1129 O O   . GLY A 1 161 ? 170.303 152.013 129.901 1.00 2.47  ? 145 GLY A O   1 
ATOM 1130 N N   . ASN A 1 162 ? 170.331 153.861 131.192 1.00 1.87  ? 146 ASN A N   1 
ATOM 1131 C CA  . ASN A 1 162 ? 169.964 153.158 132.411 1.00 1.87  ? 146 ASN A CA  1 
ATOM 1132 C C   . ASN A 1 162 ? 168.575 153.504 132.929 1.00 1.87  ? 146 ASN A C   1 
ATOM 1133 O O   . ASN A 1 162 ? 168.047 152.761 133.762 1.00 1.87  ? 146 ASN A O   1 
ATOM 1134 C CB  . ASN A 1 162 ? 171.000 153.443 133.510 1.00 1.87  ? 146 ASN A CB  1 
ATOM 1135 C CG  . ASN A 1 162 ? 170.885 152.490 134.680 1.00 1.87  ? 146 ASN A CG  1 
ATOM 1136 O OD1 . ASN A 1 162 ? 170.574 151.312 134.506 1.00 1.87  ? 146 ASN A OD1 1 
ATOM 1137 N ND2 . ASN A 1 162 ? 171.139 152.993 135.881 1.00 1.87  ? 146 ASN A ND2 1 
ATOM 1138 N N   . CYS A 1 163 ? 167.964 154.588 132.461 1.00 1.27  ? 147 CYS A N   1 
ATOM 1139 C CA  . CYS A 1 163 ? 166.667 155.008 132.993 1.00 1.27  ? 147 CYS A CA  1 
ATOM 1140 C C   . CYS A 1 163 ? 165.508 154.301 132.301 1.00 1.27  ? 147 CYS A C   1 
ATOM 1141 O O   . CYS A 1 163 ? 164.533 154.915 131.875 1.00 1.27  ? 147 CYS A O   1 
ATOM 1142 C CB  . CYS A 1 163 ? 166.526 156.520 132.890 1.00 1.27  ? 147 CYS A CB  1 
ATOM 1143 S SG  . CYS A 1 163 ? 166.757 157.202 131.242 1.00 1.27  ? 147 CYS A SG  1 
ATOM 1144 N N   . LEU A 1 164 ? 165.622 152.980 132.189 1.00 1.52  ? 148 LEU A N   1 
ATOM 1145 C CA  . LEU A 1 164 ? 164.490 152.123 131.854 1.00 1.52  ? 148 LEU A CA  1 
ATOM 1146 C C   . LEU A 1 164 ? 164.387 150.890 132.732 1.00 1.52  ? 148 LEU A C   1 
ATOM 1147 O O   . LEU A 1 164 ? 163.305 150.298 132.801 1.00 1.52  ? 148 LEU A O   1 
ATOM 1148 C CB  . LEU A 1 164 ? 164.551 151.686 130.388 1.00 1.52  ? 148 LEU A CB  1 
ATOM 1149 C CG  . LEU A 1 164 ? 163.787 152.580 129.413 1.00 1.52  ? 148 LEU A CG  1 
ATOM 1150 C CD1 . LEU A 1 164 ? 163.497 151.830 128.129 1.00 1.52  ? 148 LEU A CD1 1 
ATOM 1151 C CD2 . LEU A 1 164 ? 162.497 153.092 130.037 1.00 1.52  ? 148 LEU A CD2 1 
ATOM 1152 N N   . GLN A 1 165 ? 165.464 150.473 133.397 1.00 1.64  ? 149 GLN A N   1 
ATOM 1153 C CA  . GLN A 1 165 ? 165.398 149.456 134.432 1.00 1.64  ? 149 GLN A CA  1 
ATOM 1154 C C   . GLN A 1 165 ? 165.292 150.057 135.825 1.00 1.64  ? 149 GLN A C   1 
ATOM 1155 O O   . GLN A 1 165 ? 164.686 149.439 136.707 1.00 1.64  ? 149 GLN A O   1 
ATOM 1156 C CB  . GLN A 1 165 ? 166.628 148.542 134.353 1.00 1.64  ? 149 GLN A CB  1 
ATOM 1157 C CG  . GLN A 1 165 ? 166.687 147.458 135.415 1.00 1.64  ? 149 GLN A CG  1 
ATOM 1158 C CD  . GLN A 1 165 ? 167.727 147.741 136.479 1.00 1.64  ? 149 GLN A CD  1 
ATOM 1159 O OE1 . GLN A 1 165 ? 168.546 148.647 136.337 1.00 1.64  ? 149 GLN A OE1 1 
ATOM 1160 N NE2 . GLN A 1 165 ? 167.699 146.962 137.554 1.00 1.64  ? 149 GLN A NE2 1 
ATOM 1161 N N   . VAL A 1 166 ? 165.850 151.252 136.034 1.00 1.74  ? 150 VAL A N   1 
ATOM 1162 C CA  . VAL A 1 166 ? 165.652 151.960 137.293 1.00 1.74  ? 150 VAL A CA  1 
ATOM 1163 C C   . VAL A 1 166 ? 164.186 152.332 137.468 1.00 1.74  ? 150 VAL A C   1 
ATOM 1164 O O   . VAL A 1 166 ? 163.631 152.222 138.568 1.00 1.74  ? 150 VAL A O   1 
ATOM 1165 C CB  . VAL A 1 166 ? 166.564 153.198 137.358 1.00 1.74  ? 150 VAL A CB  1 
ATOM 1166 C CG1 . VAL A 1 166 ? 166.365 153.936 138.668 1.00 1.74  ? 150 VAL A CG1 1 
ATOM 1167 C CG2 . VAL A 1 166 ? 168.015 152.792 137.189 1.00 1.74  ? 150 VAL A CG2 1 
ATOM 1168 N N   . MET A 1 167 ? 163.536 152.780 136.391 1.00 1.96  ? 151 MET A N   1 
ATOM 1169 C CA  . MET A 1 167 ? 162.108 153.073 136.459 1.00 1.96  ? 151 MET A CA  1 
ATOM 1170 C C   . MET A 1 167 ? 161.311 151.828 136.818 1.00 1.96  ? 151 MET A C   1 
ATOM 1171 O O   . MET A 1 167 ? 160.390 151.885 137.640 1.00 1.96  ? 151 MET A O   1 
ATOM 1172 C CB  . MET A 1 167 ? 161.622 153.648 135.129 1.00 1.96  ? 151 MET A CB  1 
ATOM 1173 C CG  . MET A 1 167 ? 160.147 154.010 135.119 1.00 1.96  ? 151 MET A CG  1 
ATOM 1174 S SD  . MET A 1 167 ? 159.624 154.807 133.589 1.00 1.96  ? 151 MET A SD  1 
ATOM 1175 C CE  . MET A 1 167 ? 160.624 156.288 133.620 1.00 1.96  ? 151 MET A CE  1 
ATOM 1176 N N   . TRP A 1 168 ? 161.652 150.689 136.213 1.00 2.82  ? 152 TRP A N   1 
ATOM 1177 C CA  . TRP A 1 168 ? 161.004 149.435 136.571 1.00 2.82  ? 152 TRP A CA  1 
ATOM 1178 C C   . TRP A 1 168 ? 161.376 148.980 137.976 1.00 2.82  ? 152 TRP A C   1 
ATOM 1179 O O   . TRP A 1 168 ? 160.604 148.246 138.601 1.00 2.82  ? 152 TRP A O   1 
ATOM 1180 C CB  . TRP A 1 168 ? 161.364 148.354 135.551 1.00 2.82  ? 152 TRP A CB  1 
ATOM 1181 C CG  . TRP A 1 168 ? 160.775 147.013 135.851 1.00 2.82  ? 152 TRP A CG  1 
ATOM 1182 C CD1 . TRP A 1 168 ? 161.347 146.011 136.577 1.00 2.82  ? 152 TRP A CD1 1 
ATOM 1183 C CD2 . TRP A 1 168 ? 159.497 146.524 135.429 1.00 2.82  ? 152 TRP A CD2 1 
ATOM 1184 N NE1 . TRP A 1 168 ? 160.504 144.928 136.635 1.00 2.82  ? 152 TRP A NE1 1 
ATOM 1185 C CE2 . TRP A 1 168 ? 159.361 145.218 135.937 1.00 2.82  ? 152 TRP A CE2 1 
ATOM 1186 C CE3 . TRP A 1 168 ? 158.454 147.064 134.670 1.00 2.82  ? 152 TRP A CE3 1 
ATOM 1187 C CZ2 . TRP A 1 168 ? 158.225 144.444 135.713 1.00 2.82  ? 152 TRP A CZ2 1 
ATOM 1188 C CZ3 . TRP A 1 168 ? 157.327 146.294 134.449 1.00 2.82  ? 152 TRP A CZ3 1 
ATOM 1189 C CH2 . TRP A 1 168 ? 157.222 144.999 134.968 1.00 2.82  ? 152 TRP A CH2 1 
ATOM 1190 N N   . LEU A 1 169 ? 162.531 149.402 138.486 1.00 3.76  ? 153 LEU A N   1 
ATOM 1191 C CA  . LEU A 1 169 ? 162.969 149.062 139.833 1.00 3.76  ? 153 LEU A CA  1 
ATOM 1192 C C   . LEU A 1 169 ? 162.312 149.923 140.903 1.00 3.76  ? 153 LEU A C   1 
ATOM 1193 O O   . LEU A 1 169 ? 162.361 149.564 142.084 1.00 3.76  ? 153 LEU A O   1 
ATOM 1194 C CB  . LEU A 1 169 ? 164.494 149.190 139.937 1.00 3.76  ? 153 LEU A CB  1 
ATOM 1195 C CG  . LEU A 1 169 ? 165.177 148.630 141.186 1.00 3.76  ? 153 LEU A CG  1 
ATOM 1196 C CD1 . LEU A 1 169 ? 164.960 147.132 141.287 1.00 3.76  ? 153 LEU A CD1 1 
ATOM 1197 C CD2 . LEU A 1 169 ? 166.658 148.963 141.185 1.00 3.76  ? 153 LEU A CD2 1 
ATOM 1198 N N   . ALA A 1 170 ? 161.687 151.038 140.526 1.00 4.05  ? 154 ALA A N   1 
ATOM 1199 C CA  . ALA A 1 170 ? 161.083 151.935 141.497 1.00 4.05  ? 154 ALA A CA  1 
ATOM 1200 C C   . ALA A 1 170 ? 159.584 151.748 141.659 1.00 4.05  ? 154 ALA A C   1 
ATOM 1201 O O   . ALA A 1 170 ? 159.044 152.134 142.699 1.00 4.05  ? 154 ALA A O   1 
ATOM 1202 C CB  . ALA A 1 170 ? 161.362 153.397 141.121 1.00 4.05  ? 154 ALA A CB  1 
ATOM 1203 N N   . ASP A 1 171 ? 158.901 151.172 140.672 1.00 5.87  ? 155 ASP A N   1 
ATOM 1204 C CA  . ASP A 1 171 ? 157.474 150.906 140.796 1.00 5.87  ? 155 ASP A CA  1 
ATOM 1205 C C   . ASP A 1 171 ? 157.167 149.564 141.448 1.00 5.87  ? 155 ASP A C   1 
ATOM 1206 O O   . ASP A 1 171 ? 155.999 149.286 141.737 1.00 5.87  ? 155 ASP A O   1 
ATOM 1207 C CB  . ASP A 1 171 ? 156.788 151.036 139.419 1.00 5.87  ? 155 ASP A CB  1 
ATOM 1208 C CG  . ASP A 1 171 ? 156.814 149.749 138.579 1.00 5.87  ? 155 ASP A CG  1 
ATOM 1209 O OD1 . ASP A 1 171 ? 156.271 149.797 137.456 1.00 5.87  ? 155 ASP A OD1 1 
ATOM 1210 O OD2 . ASP A 1 171 ? 157.415 148.724 138.962 1.00 5.87  ? 155 ASP A OD2 1 
ATOM 1211 N N   . ARG A 1 172 ? 158.182 148.730 141.678 1.00 13.20 ? 156 ARG A N   1 
ATOM 1212 C CA  . ARG A 1 172 ? 157.961 147.462 142.361 1.00 13.20 ? 156 ARG A CA  1 
ATOM 1213 C C   . ARG A 1 172 ? 158.126 147.612 143.868 1.00 13.20 ? 156 ARG A C   1 
ATOM 1214 O O   . ARG A 1 172 ? 157.446 146.929 144.641 1.00 13.20 ? 156 ARG A O   1 
ATOM 1215 C CB  . ARG A 1 172 ? 158.915 146.400 141.812 1.00 13.20 ? 156 ARG A CB  1 
ATOM 1216 C CG  . ARG A 1 172 ? 158.691 145.007 142.370 1.00 13.20 ? 156 ARG A CG  1 
ATOM 1217 C CD  . ARG A 1 172 ? 159.426 143.966 141.545 1.00 13.20 ? 156 ARG A CD  1 
ATOM 1218 N NE  . ARG A 1 172 ? 160.807 144.354 141.281 1.00 13.20 ? 156 ARG A NE  1 
ATOM 1219 C CZ  . ARG A 1 172 ? 161.711 143.565 140.717 1.00 13.20 ? 156 ARG A CZ  1 
ATOM 1220 N NH1 . ARG A 1 172 ? 161.414 142.333 140.339 1.00 13.20 ? 156 ARG A NH1 1 
ATOM 1221 N NH2 . ARG A 1 172 ? 162.944 144.024 140.528 1.00 13.20 ? 156 ARG A NH2 1 
ATOM 1222 N N   . HIS A 1 173 ? 159.020 148.499 144.299 1.00 9.84  ? 157 HIS A N   1 
ATOM 1223 C CA  . HIS A 1 173 ? 159.206 148.804 145.711 1.00 9.84  ? 157 HIS A CA  1 
ATOM 1224 C C   . HIS A 1 173 ? 158.393 150.006 146.172 1.00 9.84  ? 157 HIS A C   1 
ATOM 1225 O O   . HIS A 1 173 ? 158.447 150.351 147.357 1.00 9.84  ? 157 HIS A O   1 
ATOM 1226 C CB  . HIS A 1 173 ? 160.689 149.045 146.007 1.00 9.84  ? 157 HIS A CB  1 
ATOM 1227 C CG  . HIS A 1 173 ? 161.559 147.864 145.719 1.00 9.84  ? 157 HIS A CG  1 
ATOM 1228 N ND1 . HIS A 1 173 ? 162.107 147.084 146.714 1.00 9.84  ? 157 HIS A ND1 1 
ATOM 1229 C CD2 . HIS A 1 173 ? 161.976 147.328 144.548 1.00 9.84  ? 157 HIS A CD2 1 
ATOM 1230 C CE1 . HIS A 1 173 ? 162.824 146.118 146.168 1.00 9.84  ? 157 HIS A CE1 1 
ATOM 1231 N NE2 . HIS A 1 173 ? 162.761 146.244 144.855 1.00 9.84  ? 157 HIS A NE2 1 
ATOM 1232 N N   . SER A 1 174 ? 157.647 150.643 145.270 1.00 9.84  ? 158 SER A N   1 
ATOM 1233 C CA  . SER A 1 174 ? 156.801 151.792 145.589 1.00 9.84  ? 158 SER A CA  1 
ATOM 1234 C C   . SER A 1 174 ? 157.614 152.912 146.241 1.00 9.84  ? 158 SER A C   1 
ATOM 1235 O O   . SER A 1 174 ? 157.422 153.269 147.404 1.00 9.84  ? 158 SER A O   1 
ATOM 1236 C CB  . SER A 1 174 ? 155.625 151.373 146.475 1.00 9.84  ? 158 SER A CB  1 
ATOM 1237 O OG  . SER A 1 174 ? 154.775 150.465 145.796 1.00 9.84  ? 158 SER A OG  1 
ATOM 1238 N N   . ASP A 1 175 ? 158.544 153.462 145.459 1.00 9.84  ? 159 ASP A N   1 
ATOM 1239 C CA  . ASP A 1 175 ? 159.418 154.549 145.898 1.00 9.84  ? 159 ASP A CA  1 
ATOM 1240 C C   . ASP A 1 175 ? 159.250 155.716 144.933 1.00 9.84  ? 159 ASP A C   1 
ATOM 1241 O O   . ASP A 1 175 ? 159.976 155.814 143.931 1.00 9.84  ? 159 ASP A O   1 
ATOM 1242 C CB  . ASP A 1 175 ? 160.872 154.089 145.961 1.00 9.84  ? 159 ASP A CB  1 
ATOM 1243 C CG  . ASP A 1 175 ? 161.771 155.085 146.663 1.00 9.84  ? 159 ASP A CG  1 
ATOM 1244 O OD1 . ASP A 1 175 ? 161.256 156.105 147.168 1.00 9.84  ? 159 ASP A OD1 1 
ATOM 1245 O OD2 . ASP A 1 175 ? 162.995 154.848 146.713 1.00 9.84  ? 159 ASP A OD2 1 
ATOM 1246 N N   . PRO A 1 176 ? 158.311 156.628 145.195 1.00 8.77  ? 160 PRO A N   1 
ATOM 1247 C CA  . PRO A 1 176 ? 158.056 157.729 144.255 1.00 8.77  ? 160 PRO A CA  1 
ATOM 1248 C C   . PRO A 1 176 ? 159.158 158.774 144.196 1.00 8.77  ? 160 PRO A C   1 
ATOM 1249 O O   . PRO A 1 176 ? 159.117 159.636 143.311 1.00 8.77  ? 160 PRO A O   1 
ATOM 1250 C CB  . PRO A 1 176 ? 156.748 158.354 144.773 1.00 8.77  ? 160 PRO A CB  1 
ATOM 1251 C CG  . PRO A 1 176 ? 156.343 157.596 145.978 1.00 8.77  ? 160 PRO A CG  1 
ATOM 1252 C CD  . PRO A 1 176 ? 157.399 156.620 146.350 1.00 8.77  ? 160 PRO A CD  1 
ATOM 1253 N N   . GLU A 1 177 ? 160.134 158.736 145.101 1.00 8.33  ? 161 GLU A N   1 
ATOM 1254 C CA  . GLU A 1 177 ? 161.249 159.671 145.047 1.00 8.33  ? 161 GLU A CA  1 
ATOM 1255 C C   . GLU A 1 177 ? 162.279 159.298 143.992 1.00 8.33  ? 161 GLU A C   1 
ATOM 1256 O O   . GLU A 1 177 ? 163.142 160.122 143.667 1.00 8.33  ? 161 GLU A O   1 
ATOM 1257 C CB  . GLU A 1 177 ? 161.932 159.761 146.415 1.00 8.33  ? 161 GLU A CB  1 
ATOM 1258 C CG  . GLU A 1 177 ? 160.965 159.790 147.588 1.00 8.33  ? 161 GLU A CG  1 
ATOM 1259 C CD  . GLU A 1 177 ? 161.665 159.977 148.919 1.00 8.33  ? 161 GLU A CD  1 
ATOM 1260 O OE1 . GLU A 1 177 ? 162.773 160.553 148.935 1.00 8.33  ? 161 GLU A OE1 1 
ATOM 1261 O OE2 . GLU A 1 177 ? 161.107 159.546 149.950 1.00 8.33  ? 161 GLU A OE2 1 
ATOM 1262 N N   . LEU A 1 178 ? 162.210 158.081 143.457 1.00 8.69  ? 162 LEU A N   1 
ATOM 1263 C CA  . LEU A 1 178 ? 163.084 157.623 142.383 1.00 8.69  ? 162 LEU A CA  1 
ATOM 1264 C C   . LEU A 1 178 ? 162.342 157.423 141.071 1.00 8.69  ? 162 LEU A C   1 
ATOM 1265 O O   . LEU A 1 178 ? 162.883 157.727 140.004 1.00 8.69  ? 162 LEU A O   1 
ATOM 1266 C CB  . LEU A 1 178 ? 163.769 156.314 142.782 1.00 8.69  ? 162 LEU A CB  1 
ATOM 1267 C CG  . LEU A 1 178 ? 164.689 155.687 141.737 1.00 8.69  ? 162 LEU A CG  1 
ATOM 1268 C CD1 . LEU A 1 178 ? 165.941 156.523 141.572 1.00 8.69  ? 162 LEU A CD1 1 
ATOM 1269 C CD2 . LEU A 1 178 ? 165.036 154.264 142.122 1.00 8.69  ? 162 LEU A CD2 1 
ATOM 1270 N N   . TYR A 1 179 ? 161.105 156.925 141.129 1.00 6.34  ? 163 TYR A N   1 
ATOM 1271 C CA  . TYR A 1 179 ? 160.306 156.742 139.923 1.00 6.34  ? 163 TYR A CA  1 
ATOM 1272 C C   . TYR A 1 179 ? 160.024 158.062 139.220 1.00 6.34  ? 163 TYR A C   1 
ATOM 1273 O O   . TYR A 1 179 ? 159.719 158.062 138.023 1.00 6.34  ? 163 TYR A O   1 
ATOM 1274 C CB  . TYR A 1 179 ? 159.002 156.028 140.281 1.00 6.34  ? 163 TYR A CB  1 
ATOM 1275 C CG  . TYR A 1 179 ? 158.002 155.919 139.156 1.00 6.34  ? 163 TYR A CG  1 
ATOM 1276 C CD1 . TYR A 1 179 ? 158.116 154.928 138.194 1.00 6.34  ? 163 TYR A CD1 1 
ATOM 1277 C CD2 . TYR A 1 179 ? 156.932 156.796 139.069 1.00 6.34  ? 163 TYR A CD2 1 
ATOM 1278 C CE1 . TYR A 1 179 ? 157.199 154.823 137.169 1.00 6.34  ? 163 TYR A CE1 1 
ATOM 1279 C CE2 . TYR A 1 179 ? 156.010 156.698 138.050 1.00 6.34  ? 163 TYR A CE2 1 
ATOM 1280 C CZ  . TYR A 1 179 ? 156.148 155.711 137.103 1.00 6.34  ? 163 TYR A CZ  1 
ATOM 1281 O OH  . TYR A 1 179 ? 155.229 155.613 136.085 1.00 6.34  ? 163 TYR A OH  1 
ATOM 1282 N N   . THR A 1 180 ? 160.120 159.184 139.932 1.00 9.84  ? 164 THR A N   1 
ATOM 1283 C CA  . THR A 1 180 ? 160.011 160.497 139.309 1.00 9.84  ? 164 THR A CA  1 
ATOM 1284 C C   . THR A 1 180 ? 161.370 161.079 138.945 1.00 9.84  ? 164 THR A C   1 
ATOM 1285 O O   . THR A 1 180 ? 161.481 161.795 137.943 1.00 9.84  ? 164 THR A O   1 
ATOM 1286 C CB  . THR A 1 180 ? 159.270 161.465 140.236 1.00 9.84  ? 164 THR A CB  1 
ATOM 1287 O OG1 . THR A 1 180 ? 158.066 160.849 140.707 1.00 9.84  ? 164 THR A OG1 1 
ATOM 1288 C CG2 . THR A 1 180 ? 158.914 162.744 139.497 1.00 9.84  ? 164 THR A CG2 1 
ATOM 1289 N N   . ALA A 1 181 ? 162.407 160.785 139.731 1.00 18.60 ? 165 ALA A N   1 
ATOM 1290 C CA  . ALA A 1 181 ? 163.749 161.244 139.394 1.00 18.60 ? 165 ALA A CA  1 
ATOM 1291 C C   . ALA A 1 181 ? 164.346 160.453 138.239 1.00 18.60 ? 165 ALA A C   1 
ATOM 1292 O O   . ALA A 1 181 ? 165.195 160.976 137.509 1.00 18.60 ? 165 ALA A O   1 
ATOM 1293 C CB  . ALA A 1 181 ? 164.661 161.156 140.617 1.00 18.60 ? 165 ALA A CB  1 
ATOM 1294 N N   . ALA A 1 182 ? 163.928 159.203 138.063 1.00 9.84  ? 166 ALA A N   1 
ATOM 1295 C CA  . ALA A 1 182 ? 164.327 158.400 136.917 1.00 9.84  ? 166 ALA A CA  1 
ATOM 1296 C C   . ALA A 1 182 ? 163.340 158.508 135.766 1.00 9.84  ? 166 ALA A C   1 
ATOM 1297 O O   . ALA A 1 182 ? 163.498 157.807 134.762 1.00 9.84  ? 166 ALA A O   1 
ATOM 1298 C CB  . ALA A 1 182 ? 164.492 156.935 137.323 1.00 9.84  ? 166 ALA A CB  1 
ATOM 1299 N N   . LYS A 1 183 ? 162.320 159.355 135.896 1.00 5.59  ? 167 LYS A N   1 
ATOM 1300 C CA  . LYS A 1 183 ? 161.395 159.617 134.802 1.00 5.59  ? 167 LYS A CA  1 
ATOM 1301 C C   . LYS A 1 183 ? 161.867 160.766 133.924 1.00 5.59  ? 167 LYS A C   1 
ATOM 1302 O O   . LYS A 1 183 ? 161.662 160.736 132.707 1.00 5.59  ? 167 LYS A O   1 
ATOM 1303 C CB  . LYS A 1 183 ? 159.997 159.920 135.345 1.00 5.59  ? 167 LYS A CB  1 
ATOM 1304 C CG  . LYS A 1 183 ? 158.923 159.977 134.274 1.00 5.59  ? 167 LYS A CG  1 
ATOM 1305 C CD  . LYS A 1 183 ? 157.653 160.621 134.799 1.00 5.59  ? 167 LYS A CD  1 
ATOM 1306 C CE  . LYS A 1 183 ? 157.048 159.805 135.925 1.00 5.59  ? 167 LYS A CE  1 
ATOM 1307 N NZ  . LYS A 1 183 ? 156.645 158.453 135.459 1.00 5.59  ? 167 LYS A NZ  1 
ATOM 1308 N N   . HIS A 1 184 ? 162.506 161.780 134.511 1.00 3.86  ? 168 HIS A N   1 
ATOM 1309 C CA  . HIS A 1 184 ? 163.058 162.858 133.703 1.00 3.86  ? 168 HIS A CA  1 
ATOM 1310 C C   . HIS A 1 184 ? 164.442 162.478 133.195 1.00 3.86  ? 168 HIS A C   1 
ATOM 1311 O O   . HIS A 1 184 ? 165.386 163.269 133.282 1.00 3.86  ? 168 HIS A O   1 
ATOM 1312 C CB  . HIS A 1 184 ? 163.128 164.160 134.503 1.00 3.86  ? 168 HIS A CB  1 
ATOM 1313 C CG  . HIS A 1 184 ? 161.927 164.411 135.361 1.00 3.86  ? 168 HIS A CG  1 
ATOM 1314 N ND1 . HIS A 1 184 ? 162.023 164.765 136.689 1.00 3.86  ? 168 HIS A ND1 1 
ATOM 1315 C CD2 . HIS A 1 184 ? 160.604 164.367 135.078 1.00 3.86  ? 168 HIS A CD2 1 
ATOM 1316 C CE1 . HIS A 1 184 ? 160.811 164.924 137.189 1.00 3.86  ? 168 HIS A CE1 1 
ATOM 1317 N NE2 . HIS A 1 184 ? 159.931 164.689 136.232 1.00 3.86  ? 168 HIS A NE2 1 
ATOM 1318 N N   . CYS A 1 185 ? 164.564 161.274 132.673 1.00 2.24  ? 169 CYS A N   1 
ATOM 1319 C CA  . CYS A 1 185 ? 165.678 160.828 131.847 1.00 2.24  ? 169 CYS A CA  1 
ATOM 1320 C C   . CYS A 1 185 ? 165.201 160.144 130.578 1.00 2.24  ? 169 CYS A C   1 
ATOM 1321 O O   . CYS A 1 185 ? 165.812 160.320 129.523 1.00 2.24  ? 169 CYS A O   1 
ATOM 1322 C CB  . CYS A 1 185 ? 166.592 159.883 132.632 1.00 2.24  ? 169 CYS A CB  1 
ATOM 1323 S SG  . CYS A 1 185 ? 167.732 158.950 131.590 1.00 2.24  ? 169 CYS A SG  1 
ATOM 1324 N N   . ALA A 1 186 ? 164.119 159.372 130.655 1.00 1.91  ? 170 ALA A N   1 
ATOM 1325 C CA  . ALA A 1 186 ? 163.506 158.769 129.484 1.00 1.91  ? 170 ALA A CA  1 
ATOM 1326 C C   . ALA A 1 186 ? 162.431 159.649 128.866 1.00 1.91  ? 170 ALA A C   1 
ATOM 1327 O O   . ALA A 1 186 ? 161.867 159.278 127.832 1.00 1.91  ? 170 ALA A O   1 
ATOM 1328 C CB  . ALA A 1 186 ? 162.905 157.406 129.841 1.00 1.91  ? 170 ALA A CB  1 
ATOM 1329 N N   . LYS A 1 187 ? 162.134 160.797 129.474 1.00 3.16  ? 171 LYS A N   1 
ATOM 1330 C CA  . LYS A 1 187 ? 161.164 161.732 128.919 1.00 3.16  ? 171 LYS A CA  1 
ATOM 1331 C C   . LYS A 1 187 ? 161.841 162.871 128.168 1.00 3.16  ? 171 LYS A C   1 
ATOM 1332 O O   . LYS A 1 187 ? 161.315 163.342 127.155 1.00 3.16  ? 171 LYS A O   1 
ATOM 1333 C CB  . LYS A 1 187 ? 160.265 162.277 130.035 1.00 3.16  ? 171 LYS A CB  1 
ATOM 1334 C CG  . LYS A 1 187 ? 159.936 163.759 129.945 1.00 3.16  ? 171 LYS A CG  1 
ATOM 1335 C CD  . LYS A 1 187 ? 159.282 164.244 131.230 1.00 3.16  ? 171 LYS A CD  1 
ATOM 1336 C CE  . LYS A 1 187 ? 159.341 165.757 131.369 1.00 3.16  ? 171 LYS A CE  1 
ATOM 1337 N NZ  . LYS A 1 187 ? 160.728 166.274 131.486 1.00 3.16  ? 171 LYS A NZ  1 
ATOM 1338 N N   . THR A 1 188 ? 163.008 163.312 128.632 1.00 2.48  ? 172 THR A N   1 
ATOM 1339 C CA  . THR A 1 188 ? 163.785 164.329 127.937 1.00 2.48  ? 172 THR A CA  1 
ATOM 1340 C C   . THR A 1 188 ? 164.816 163.738 126.983 1.00 2.48  ? 172 THR A C   1 
ATOM 1341 O O   . THR A 1 188 ? 165.523 164.498 126.313 1.00 2.48  ? 172 THR A O   1 
ATOM 1342 C CB  . THR A 1 188 ? 164.488 165.244 128.945 1.00 2.48  ? 172 THR A CB  1 
ATOM 1343 O OG1 . THR A 1 188 ? 165.701 164.626 129.388 1.00 2.48  ? 172 THR A OG1 1 
ATOM 1344 C CG2 . THR A 1 188 ? 163.596 165.501 130.142 1.00 2.48  ? 172 THR A CG2 1 
ATOM 1345 N N   . HIS A 1 189 ? 164.922 162.413 126.907 1.00 3.18  ? 173 HIS A N   1 
ATOM 1346 C CA  . HIS A 1 189 ? 165.842 161.745 125.991 1.00 3.18  ? 173 HIS A CA  1 
ATOM 1347 C C   . HIS A 1 189 ? 165.150 160.578 125.303 1.00 3.18  ? 173 HIS A C   1 
ATOM 1348 O O   . HIS A 1 189 ? 165.753 159.525 125.072 1.00 3.18  ? 173 HIS A O   1 
ATOM 1349 C CB  . HIS A 1 189 ? 167.097 161.261 126.714 1.00 3.18  ? 173 HIS A CB  1 
ATOM 1350 C CG  . HIS A 1 189 ? 167.937 162.361 127.284 1.00 3.18  ? 173 HIS A CG  1 
ATOM 1351 N ND1 . HIS A 1 189 ? 167.628 163.001 128.464 1.00 3.18  ? 173 HIS A ND1 1 
ATOM 1352 C CD2 . HIS A 1 189 ? 169.087 162.922 126.842 1.00 3.18  ? 173 HIS A CD2 1 
ATOM 1353 C CE1 . HIS A 1 189 ? 168.548 163.915 128.721 1.00 3.18  ? 173 HIS A CE1 1 
ATOM 1354 N NE2 . HIS A 1 189 ? 169.444 163.888 127.751 1.00 3.18  ? 173 HIS A NE2 1 
ATOM 1355 N N   . LEU A 1 190 ? 163.870 160.748 124.966 1.00 4.68  ? 174 LEU A N   1 
ATOM 1356 C CA  . LEU A 1 190 ? 163.103 159.664 124.364 1.00 4.68  ? 174 LEU A CA  1 
ATOM 1357 C C   . LEU A 1 190 ? 163.547 159.349 122.941 1.00 4.68  ? 174 LEU A C   1 
ATOM 1358 O O   . LEU A 1 190 ? 163.318 158.230 122.469 1.00 4.68  ? 174 LEU A O   1 
ATOM 1359 C CB  . LEU A 1 190 ? 161.613 160.009 124.383 1.00 4.68  ? 174 LEU A CB  1 
ATOM 1360 C CG  . LEU A 1 190 ? 160.623 158.885 124.074 1.00 4.68  ? 174 LEU A CG  1 
ATOM 1361 C CD1 . LEU A 1 190 ? 160.665 157.818 125.151 1.00 4.68  ? 174 LEU A CD1 1 
ATOM 1362 C CD2 . LEU A 1 190 ? 159.220 159.443 123.930 1.00 4.68  ? 174 LEU A CD2 1 
ATOM 1363 N N   . ALA A 1 191 ? 164.175 160.303 122.249 1.00 6.93  ? 175 ALA A N   1 
ATOM 1364 C CA  . ALA A 1 191 ? 164.558 160.083 120.857 1.00 6.93  ? 175 ALA A CA  1 
ATOM 1365 C C   . ALA A 1 191 ? 165.570 158.951 120.731 1.00 6.93  ? 175 ALA A C   1 
ATOM 1366 O O   . ALA A 1 191 ? 165.438 158.078 119.865 1.00 6.93  ? 175 ALA A O   1 
ATOM 1367 C CB  . ALA A 1 191 ? 165.114 161.374 120.257 1.00 6.93  ? 175 ALA A CB  1 
ATOM 1368 N N   . GLN A 1 192 ? 166.595 158.950 121.587 1.00 6.89  ? 176 GLN A N   1 
ATOM 1369 C CA  . GLN A 1 192 ? 167.600 157.894 121.529 1.00 6.89  ? 176 GLN A CA  1 
ATOM 1370 C C   . GLN A 1 192 ? 167.036 156.558 121.997 1.00 6.89  ? 176 GLN A C   1 
ATOM 1371 O O   . GLN A 1 192 ? 167.422 155.505 121.477 1.00 6.89  ? 176 GLN A O   1 
ATOM 1372 C CB  . GLN A 1 192 ? 168.819 158.285 122.365 1.00 6.89  ? 176 GLN A CB  1 
ATOM 1373 C CG  . GLN A 1 192 ? 169.836 157.171 122.550 1.00 6.89  ? 176 GLN A CG  1 
ATOM 1374 C CD  . GLN A 1 192 ? 170.925 157.534 123.537 1.00 6.89  ? 176 GLN A CD  1 
ATOM 1375 O OE1 . GLN A 1 192 ? 171.055 158.690 123.939 1.00 6.89  ? 176 GLN A OE1 1 
ATOM 1376 N NE2 . GLN A 1 192 ? 171.719 156.545 123.929 1.00 6.89  ? 176 GLN A NE2 1 
ATOM 1377 N N   . LEU A 1 193 ? 166.116 156.582 122.961 1.00 7.32  ? 177 LEU A N   1 
ATOM 1378 C CA  . LEU A 1 193 ? 165.509 155.369 123.492 1.00 7.32  ? 177 LEU A CA  1 
ATOM 1379 C C   . LEU A 1 193 ? 164.556 154.698 122.511 1.00 7.32  ? 177 LEU A C   1 
ATOM 1380 O O   . LEU A 1 193 ? 164.115 153.574 122.777 1.00 7.32  ? 177 LEU A O   1 
ATOM 1381 C CB  . LEU A 1 193 ? 164.766 155.691 124.789 1.00 7.32  ? 177 LEU A CB  1 
ATOM 1382 C CG  . LEU A 1 193 ? 165.505 155.411 126.095 1.00 7.32  ? 177 LEU A CG  1 
ATOM 1383 C CD1 . LEU A 1 193 ? 166.487 156.524 126.404 1.00 7.32  ? 177 LEU A CD1 1 
ATOM 1384 C CD2 . LEU A 1 193 ? 164.503 155.274 127.216 1.00 7.32  ? 177 LEU A CD2 1 
ATOM 1385 N N   . GLN A 1 194 ? 164.229 155.356 121.396 1.00 10.81 ? 178 GLN A N   1 
ATOM 1386 C CA  . GLN A 1 194 ? 163.281 154.791 120.441 1.00 10.81 ? 178 GLN A CA  1 
ATOM 1387 C C   . GLN A 1 194 ? 163.781 153.480 119.853 1.00 10.81 ? 178 GLN A C   1 
ATOM 1388 O O   . GLN A 1 194 ? 163.010 152.522 119.724 1.00 10.81 ? 178 GLN A O   1 
ATOM 1389 C CB  . GLN A 1 194 ? 163.015 155.798 119.323 1.00 10.81 ? 178 GLN A CB  1 
ATOM 1390 C CG  . GLN A 1 194 ? 161.722 156.578 119.464 1.00 10.81 ? 178 GLN A CG  1 
ATOM 1391 C CD  . GLN A 1 194 ? 161.498 157.528 118.306 1.00 10.81 ? 178 GLN A CD  1 
ATOM 1392 O OE1 . GLN A 1 194 ? 160.379 157.975 118.060 1.00 10.81 ? 178 GLN A OE1 1 
ATOM 1393 N NE2 . GLN A 1 194 ? 162.568 157.842 117.585 1.00 10.81 ? 178 GLN A NE2 1 
ATOM 1394 N N   . ASN A 1 195 ? 165.060 153.416 119.491 1.00 13.30 ? 179 ASN A N   1 
ATOM 1395 C CA  . ASN A 1 195 ? 165.639 152.234 118.869 1.00 13.30 ? 179 ASN A CA  1 
ATOM 1396 C C   . ASN A 1 195 ? 166.011 151.150 119.875 1.00 13.30 ? 179 ASN A C   1 
ATOM 1397 O O   . ASN A 1 195 ? 166.095 149.977 119.494 1.00 13.30 ? 179 ASN A O   1 
ATOM 1398 C CB  . ASN A 1 195 ? 166.873 152.642 118.049 1.00 13.30 ? 179 ASN A CB  1 
ATOM 1399 C CG  . ASN A 1 195 ? 167.828 151.491 117.803 1.00 13.30 ? 179 ASN A CG  1 
ATOM 1400 O OD1 . ASN A 1 195 ? 167.591 150.648 116.937 1.00 13.30 ? 179 ASN A OD1 1 
ATOM 1401 N ND2 . ASN A 1 195 ? 168.916 151.451 118.563 1.00 13.30 ? 179 ASN A ND2 1 
ATOM 1402 N N   . THR A 1 196 ? 166.197 151.503 121.143 1.00 12.91 ? 180 THR A N   1 
ATOM 1403 C CA  . THR A 1 196 ? 166.646 150.566 122.161 1.00 12.91 ? 180 THR A CA  1 
ATOM 1404 C C   . THR A 1 196 ? 165.640 149.434 122.344 1.00 12.91 ? 180 THR A C   1 
ATOM 1405 O O   . THR A 1 196 ? 164.424 149.629 122.284 1.00 12.91 ? 180 THR A O   1 
ATOM 1406 C CB  . THR A 1 196 ? 166.870 151.283 123.493 1.00 12.91 ? 180 THR A CB  1 
ATOM 1407 O OG1 . THR A 1 196 ? 167.354 152.609 123.247 1.00 12.91 ? 180 THR A OG1 1 
ATOM 1408 C CG2 . THR A 1 196 ? 167.887 150.530 124.337 1.00 12.91 ? 180 THR A CG2 1 
ATOM 1409 N N   . GLU A 1 197 ? 166.171 148.232 122.570 1.00 14.05 ? 181 GLU A N   1 
ATOM 1410 C CA  . GLU A 1 197 ? 165.344 147.044 122.730 1.00 14.05 ? 181 GLU A CA  1 
ATOM 1411 C C   . GLU A 1 197 ? 164.610 147.001 124.062 1.00 14.05 ? 181 GLU A C   1 
ATOM 1412 O O   . GLU A 1 197 ? 163.607 146.288 124.176 1.00 14.05 ? 181 GLU A O   1 
ATOM 1413 C CB  . GLU A 1 197 ? 166.199 145.781 122.586 1.00 14.05 ? 181 GLU A CB  1 
ATOM 1414 C CG  . GLU A 1 197 ? 166.465 145.364 121.146 1.00 14.05 ? 181 GLU A CG  1 
ATOM 1415 C CD  . GLU A 1 197 ? 167.464 146.268 120.448 1.00 14.05 ? 181 GLU A CD  1 
ATOM 1416 O OE1 . GLU A 1 197 ? 168.200 146.998 121.144 1.00 14.05 ? 181 GLU A OE1 1 
ATOM 1417 O OE2 . GLU A 1 197 ? 167.515 146.247 119.200 1.00 14.05 ? 181 GLU A OE2 1 
ATOM 1418 N N   . GLU A 1 198 ? 165.086 147.735 125.070 1.00 8.34  ? 182 GLU A N   1 
ATOM 1419 C CA  . GLU A 1 198 ? 164.400 147.770 126.356 1.00 8.34  ? 182 GLU A CA  1 
ATOM 1420 C C   . GLU A 1 198 ? 163.084 148.534 126.285 1.00 8.34  ? 182 GLU A C   1 
ATOM 1421 O O   . GLU A 1 198 ? 162.142 148.193 127.008 1.00 8.34  ? 182 GLU A O   1 
ATOM 1422 C CB  . GLU A 1 198 ? 165.311 148.392 127.416 1.00 8.34  ? 182 GLU A CB  1 
ATOM 1423 C CG  . GLU A 1 198 ? 164.747 148.361 128.826 1.00 8.34  ? 182 GLU A CG  1 
ATOM 1424 C CD  . GLU A 1 198 ? 164.762 146.972 129.431 1.00 8.34  ? 182 GLU A CD  1 
ATOM 1425 O OE1 . GLU A 1 198 ? 165.553 146.127 128.962 1.00 8.34  ? 182 GLU A OE1 1 
ATOM 1426 O OE2 . GLU A 1 198 ? 163.983 146.724 130.376 1.00 8.34  ? 182 GLU A OE2 1 
ATOM 1427 N N   . PHE A 1 199 ? 162.998 149.553 125.428 1.00 9.53  ? 183 PHE A N   1 
ATOM 1428 C CA  . PHE A 1 199 ? 161.780 150.346 125.314 1.00 9.53  ? 183 PHE A CA  1 
ATOM 1429 C C   . PHE A 1 199 ? 160.646 149.574 124.654 1.00 9.53  ? 183 PHE A C   1 
ATOM 1430 O O   . PHE A 1 199 ? 159.473 149.885 124.888 1.00 9.53  ? 183 PHE A O   1 
ATOM 1431 C CB  . PHE A 1 199 ? 162.071 151.629 124.533 1.00 9.53  ? 183 PHE A CB  1 
ATOM 1432 C CG  . PHE A 1 199 ? 160.876 152.519 124.354 1.00 9.53  ? 183 PHE A CG  1 
ATOM 1433 C CD1 . PHE A 1 199 ? 160.419 153.304 125.397 1.00 9.53  ? 183 PHE A CD1 1 
ATOM 1434 C CD2 . PHE A 1 199 ? 160.217 152.577 123.140 1.00 9.53  ? 183 PHE A CD2 1 
ATOM 1435 C CE1 . PHE A 1 199 ? 159.323 154.125 125.233 1.00 9.53  ? 183 PHE A CE1 1 
ATOM 1436 C CE2 . PHE A 1 199 ? 159.121 153.397 122.970 1.00 9.53  ? 183 PHE A CE2 1 
ATOM 1437 C CZ  . PHE A 1 199 ? 158.674 154.172 124.018 1.00 9.53  ? 183 PHE A CZ  1 
ATOM 1438 N N   . LEU A 1 200 ? 160.967 148.571 123.834 1.00 14.15 ? 184 LEU A N   1 
ATOM 1439 C CA  . LEU A 1 200 ? 159.932 147.829 123.126 1.00 14.15 ? 184 LEU A CA  1 
ATOM 1440 C C   . LEU A 1 200 ? 159.106 146.946 124.052 1.00 14.15 ? 184 LEU A C   1 
ATOM 1441 O O   . LEU A 1 200 ? 157.956 146.635 123.726 1.00 14.15 ? 184 LEU A O   1 
ATOM 1442 C CB  . LEU A 1 200 ? 160.560 146.981 122.019 1.00 14.15 ? 184 LEU A CB  1 
ATOM 1443 C CG  . LEU A 1 200 ? 161.060 147.730 120.781 1.00 14.15 ? 184 LEU A CG  1 
ATOM 1444 C CD1 . LEU A 1 200 ? 161.061 146.816 119.567 1.00 14.15 ? 184 LEU A CD1 1 
ATOM 1445 C CD2 . LEU A 1 200 ? 160.223 148.973 120.514 1.00 14.15 ? 184 LEU A CD2 1 
ATOM 1446 N N   . HIS A 1 201 ? 159.659 146.537 125.192 1.00 14.35 ? 185 HIS A N   1 
ATOM 1447 C CA  . HIS A 1 201 ? 158.959 145.680 126.139 1.00 14.35 ? 185 HIS A CA  1 
ATOM 1448 C C   . HIS A 1 201 ? 158.333 146.458 127.288 1.00 14.35 ? 185 HIS A C   1 
ATOM 1449 O O   . HIS A 1 201 ? 157.885 145.847 128.264 1.00 14.35 ? 185 HIS A O   1 
ATOM 1450 C CB  . HIS A 1 201 ? 159.909 144.614 126.689 1.00 14.35 ? 185 HIS A CB  1 
ATOM 1451 C CG  . HIS A 1 201 ? 160.197 143.506 125.726 1.00 14.35 ? 185 HIS A CG  1 
ATOM 1452 N ND1 . HIS A 1 201 ? 159.297 142.495 125.464 1.00 14.35 ? 185 HIS A ND1 1 
ATOM 1453 C CD2 . HIS A 1 201 ? 161.285 143.247 124.963 1.00 14.35 ? 185 HIS A CD2 1 
ATOM 1454 C CE1 . HIS A 1 201 ? 159.818 141.663 124.581 1.00 14.35 ? 185 HIS A CE1 1 
ATOM 1455 N NE2 . HIS A 1 201 ? 161.024 142.096 124.260 1.00 14.35 ? 185 HIS A NE2 1 
ATOM 1456 N N   . LEU A 1 202 ? 158.296 147.779 127.200 1.00 11.11 ? 186 LEU A N   1 
ATOM 1457 C CA  . LEU A 1 202 ? 157.740 148.592 128.276 1.00 11.11 ? 186 LEU A CA  1 
ATOM 1458 C C   . LEU A 1 202 ? 156.234 148.387 128.366 1.00 11.11 ? 186 LEU A C   1 
ATOM 1459 O O   . LEU A 1 202 ? 155.537 148.537 127.354 1.00 11.11 ? 186 LEU A O   1 
ATOM 1460 C CB  . LEU A 1 202 ? 158.064 150.064 128.046 1.00 11.11 ? 186 LEU A CB  1 
ATOM 1461 C CG  . LEU A 1 202 ? 158.133 150.948 129.290 1.00 11.11 ? 186 LEU A CG  1 
ATOM 1462 C CD1 . LEU A 1 202 ? 159.068 150.343 130.323 1.00 11.11 ? 186 LEU A CD1 1 
ATOM 1463 C CD2 . LEU A 1 202 ? 158.579 152.351 128.920 1.00 11.11 ? 186 LEU A CD2 1 
ATOM 1464 N N   . PRO A 1 203 ? 155.693 148.041 129.533 1.00 11.45 ? 187 PRO A N   1 
ATOM 1465 C CA  . PRO A 1 203 ? 154.243 147.862 129.653 1.00 11.45 ? 187 PRO A CA  1 
ATOM 1466 C C   . PRO A 1 203 ? 153.500 149.175 129.461 1.00 11.45 ? 187 PRO A C   1 
ATOM 1467 O O   . PRO A 1 203 ? 154.049 150.265 129.632 1.00 11.45 ? 187 PRO A O   1 
ATOM 1468 C CB  . PRO A 1 203 ? 154.065 147.325 131.079 1.00 11.45 ? 187 PRO A CB  1 
ATOM 1469 C CG  . PRO A 1 203 ? 155.406 146.777 131.454 1.00 11.45 ? 187 PRO A CG  1 
ATOM 1470 C CD  . PRO A 1 203 ? 156.401 147.656 130.764 1.00 11.45 ? 187 PRO A CD  1 
ATOM 1471 N N   . HIS A 1 204 ? 152.223 149.053 129.093 1.00 11.93 ? 188 HIS A N   1 
ATOM 1472 C CA  . HIS A 1 204 ? 151.397 150.230 128.852 1.00 11.93 ? 188 HIS A CA  1 
ATOM 1473 C C   . HIS A 1 204 ? 151.229 151.089 130.098 1.00 11.93 ? 188 HIS A C   1 
ATOM 1474 O O   . HIS A 1 204 ? 150.987 152.295 129.977 1.00 11.93 ? 188 HIS A O   1 
ATOM 1475 C CB  . HIS A 1 204 ? 150.028 149.801 128.320 1.00 11.93 ? 188 HIS A CB  1 
ATOM 1476 C CG  . HIS A 1 204 ? 149.031 150.915 128.243 1.00 11.93 ? 188 HIS A CG  1 
ATOM 1477 N ND1 . HIS A 1 204 ? 149.305 152.117 127.629 1.00 11.93 ? 188 HIS A ND1 1 
ATOM 1478 C CD2 . HIS A 1 204 ? 147.762 151.009 128.705 1.00 11.93 ? 188 HIS A CD2 1 
ATOM 1479 C CE1 . HIS A 1 204 ? 148.248 152.904 127.715 1.00 11.93 ? 188 HIS A CE1 1 
ATOM 1480 N NE2 . HIS A 1 204 ? 147.298 152.256 128.364 1.00 11.93 ? 188 HIS A NE2 1 
ATOM 1481 N N   . ARG A 1 205 ? 151.356 150.501 131.290 1.00 9.50  ? 189 ARG A N   1 
ATOM 1482 C CA  . ARG A 1 205 ? 151.172 151.270 132.518 1.00 9.50  ? 189 ARG A CA  1 
ATOM 1483 C C   . ARG A 1 205 ? 152.227 152.360 132.663 1.00 9.50  ? 189 ARG A C   1 
ATOM 1484 O O   . ARG A 1 205 ? 151.902 153.503 133.003 1.00 9.50  ? 189 ARG A O   1 
ATOM 1485 C CB  . ARG A 1 205 ? 151.201 150.338 133.728 1.00 9.50  ? 189 ARG A CB  1 
ATOM 1486 C CG  . ARG A 1 205 ? 151.198 151.063 135.062 1.00 9.50  ? 189 ARG A CG  1 
ATOM 1487 C CD  . ARG A 1 205 ? 151.324 150.089 136.218 1.00 9.50  ? 189 ARG A CD  1 
ATOM 1488 N NE  . ARG A 1 205 ? 151.220 150.759 137.508 1.00 9.50  ? 189 ARG A NE  1 
ATOM 1489 C CZ  . ARG A 1 205 ? 151.447 150.173 138.676 1.00 9.50  ? 189 ARG A CZ  1 
ATOM 1490 N NH1 . ARG A 1 205 ? 151.795 148.899 138.754 1.00 9.50  ? 189 ARG A NH1 1 
ATOM 1491 N NH2 . ARG A 1 205 ? 151.322 150.883 139.793 1.00 9.50  ? 189 ARG A NH2 1 
ATOM 1492 N N   . LEU A 1 206 ? 153.493 152.029 132.413 1.00 5.95  ? 190 LEU A N   1 
ATOM 1493 C CA  . LEU A 1 206 ? 154.573 152.997 132.559 1.00 5.95  ? 190 LEU A CA  1 
ATOM 1494 C C   . LEU A 1 206 ? 154.642 153.990 131.409 1.00 5.95  ? 190 LEU A C   1 
ATOM 1495 O O   . LEU A 1 206 ? 155.035 155.142 131.621 1.00 5.95  ? 190 LEU A O   1 
ATOM 1496 C CB  . LEU A 1 206 ? 155.917 152.276 132.685 1.00 5.95  ? 190 LEU A CB  1 
ATOM 1497 C CG  . LEU A 1 206 ? 156.055 151.298 133.850 1.00 5.95  ? 190 LEU A CG  1 
ATOM 1498 C CD1 . LEU A 1 206 ? 157.350 150.515 133.740 1.00 5.95  ? 190 LEU A CD1 1 
ATOM 1499 C CD2 . LEU A 1 206 ? 155.992 152.046 135.168 1.00 5.95  ? 190 LEU A CD2 1 
ATOM 1500 N N   . LEU A 1 207 ? 154.268 153.573 130.198 1.00 6.48  ? 191 LEU A N   1 
ATOM 1501 C CA  . LEU A 1 207 ? 154.412 154.440 129.036 1.00 6.48  ? 191 LEU A CA  1 
ATOM 1502 C C   . LEU A 1 207 ? 153.410 155.588 129.058 1.00 6.48  ? 191 LEU A C   1 
ATOM 1503 O O   . LEU A 1 207 ? 153.692 156.653 128.502 1.00 6.48  ? 191 LEU A O   1 
ATOM 1504 C CB  . LEU A 1 207 ? 154.270 153.601 127.762 1.00 6.48  ? 191 LEU A CB  1 
ATOM 1505 C CG  . LEU A 1 207 ? 154.901 153.977 126.414 1.00 6.48  ? 191 LEU A CG  1 
ATOM 1506 C CD1 . LEU A 1 207 ? 154.454 152.976 125.378 1.00 6.48  ? 191 LEU A CD1 1 
ATOM 1507 C CD2 . LEU A 1 207 ? 154.575 155.369 125.929 1.00 6.48  ? 191 LEU A CD2 1 
ATOM 1508 N N   . THR A 1 208 ? 152.270 155.415 129.721 1.00 7.60  ? 192 THR A N   1 
ATOM 1509 C CA  . THR A 1 208 ? 151.300 156.492 129.859 1.00 7.60  ? 192 THR A CA  1 
ATOM 1510 C C   . THR A 1 208 ? 151.757 157.568 130.835 1.00 7.60  ? 192 THR A C   1 
ATOM 1511 O O   . THR A 1 208 ? 151.112 158.618 130.925 1.00 7.60  ? 192 THR A O   1 
ATOM 1512 C CB  . THR A 1 208 ? 149.941 155.932 130.298 1.00 7.60  ? 192 THR A CB  1 
ATOM 1513 O OG1 . THR A 1 208 ? 148.896 156.799 129.840 1.00 7.60  ? 192 THR A OG1 1 
ATOM 1514 C CG2 . THR A 1 208 ? 149.868 155.808 131.813 1.00 7.60  ? 192 THR A CG2 1 
ATOM 1515 N N   . ASP A 1 209 ? 152.851 157.337 131.560 1.00 4.71  ? 193 ASP A N   1 
ATOM 1516 C CA  . ASP A 1 209 ? 153.430 158.332 132.452 1.00 4.71  ? 193 ASP A CA  1 
ATOM 1517 C C   . ASP A 1 209 ? 154.614 159.070 131.850 1.00 4.71  ? 193 ASP A C   1 
ATOM 1518 O O   . ASP A 1 209 ? 154.808 160.248 132.155 1.00 4.71  ? 193 ASP A O   1 
ATOM 1519 C CB  . ASP A 1 209 ? 153.875 157.675 133.765 1.00 4.71  ? 193 ASP A CB  1 
ATOM 1520 C CG  . ASP A 1 209 ? 152.708 157.191 134.599 1.00 4.71  ? 193 ASP A CG  1 
ATOM 1521 O OD1 . ASP A 1 209 ? 151.551 157.411 134.186 1.00 4.71  ? 193 ASP A OD1 1 
ATOM 1522 O OD2 . ASP A 1 209 ? 152.947 156.591 135.667 1.00 4.71  ? 193 ASP A OD2 1 
ATOM 1523 N N   . ILE A 1 210 ? 155.412 158.406 131.012 1.00 3.63  ? 194 ILE A N   1 
ATOM 1524 C CA  . ILE A 1 210 ? 156.532 159.076 130.359 1.00 3.63  ? 194 ILE A CA  1 
ATOM 1525 C C   . ILE A 1 210 ? 156.026 160.131 129.383 1.00 3.63  ? 194 ILE A C   1 
ATOM 1526 O O   . ILE A 1 210 ? 156.532 161.258 129.343 1.00 3.63  ? 194 ILE A O   1 
ATOM 1527 C CB  . ILE A 1 210 ? 157.435 158.047 129.655 1.00 3.63  ? 194 ILE A CB  1 
ATOM 1528 C CG1 . ILE A 1 210 ? 158.037 157.081 130.675 1.00 3.63  ? 194 ILE A CG1 1 
ATOM 1529 C CG2 . ILE A 1 210 ? 158.530 158.745 128.870 1.00 3.63  ? 194 ILE A CG2 1 
ATOM 1530 C CD1 . ILE A 1 210 ? 158.898 156.006 130.056 1.00 3.63  ? 194 ILE A CD1 1 
ATOM 1531 N N   . ILE A 1 211 ? 155.019 159.780 128.581 1.00 4.99  ? 195 ILE A N   1 
ATOM 1532 C CA  . ILE A 1 211 ? 154.499 160.711 127.585 1.00 4.99  ? 195 ILE A CA  1 
ATOM 1533 C C   . ILE A 1 211 ? 153.743 161.853 128.252 1.00 4.99  ? 195 ILE A C   1 
ATOM 1534 O O   . ILE A 1 211 ? 153.899 163.021 127.876 1.00 4.99  ? 195 ILE A O   1 
ATOM 1535 C CB  . ILE A 1 211 ? 153.616 159.965 126.570 1.00 4.99  ? 195 ILE A CB  1 
ATOM 1536 C CG1 . ILE A 1 211 ? 154.428 158.886 125.858 1.00 4.99  ? 195 ILE A CG1 1 
ATOM 1537 C CG2 . ILE A 1 211 ? 153.029 160.931 125.562 1.00 4.99  ? 195 ILE A CG2 1 
ATOM 1538 C CD1 . ILE A 1 211 ? 155.453 159.431 124.896 1.00 4.99  ? 195 ILE A CD1 1 
ATOM 1539 N N   . SER A 1 212 ? 152.924 161.543 129.254 1.00 6.62  ? 196 SER A N   1 
ATOM 1540 C CA  . SER A 1 212 ? 152.060 162.535 129.882 1.00 6.62  ? 196 SER A CA  1 
ATOM 1541 C C   . SER A 1 212 ? 152.815 163.523 130.761 1.00 6.62  ? 196 SER A C   1 
ATOM 1542 O O   . SER A 1 212 ? 152.202 164.473 131.259 1.00 6.62  ? 196 SER A O   1 
ATOM 1543 C CB  . SER A 1 212 ? 150.978 161.841 130.712 1.00 6.62  ? 196 SER A CB  1 
ATOM 1544 O OG  . SER A 1 212 ? 150.157 162.789 131.370 1.00 6.62  ? 196 SER A OG  1 
ATOM 1545 N N   . ASP A 1 213 ? 154.114 163.331 130.966 1.00 5.81  ? 197 ASP A N   1 
ATOM 1546 C CA  . ASP A 1 213 ? 154.890 164.180 131.857 1.00 5.81  ? 197 ASP A CA  1 
ATOM 1547 C C   . ASP A 1 213 ? 155.455 165.416 131.167 1.00 5.81  ? 197 ASP A C   1 
ATOM 1548 O O   . ASP A 1 213 ? 156.196 166.174 131.800 1.00 5.81  ? 197 ASP A O   1 
ATOM 1549 C CB  . ASP A 1 213 ? 156.032 163.375 132.488 1.00 5.81  ? 197 ASP A CB  1 
ATOM 1550 C CG  . ASP A 1 213 ? 156.411 163.881 133.866 1.00 5.81  ? 197 ASP A CG  1 
ATOM 1551 O OD1 . ASP A 1 213 ? 155.694 163.559 134.837 1.00 5.81  ? 197 ASP A OD1 1 
ATOM 1552 O OD2 . ASP A 1 213 ? 157.425 164.601 133.979 1.00 5.81  ? 197 ASP A OD2 1 
ATOM 1553 N N   . GLY A 1 214 ? 155.120 165.646 129.899 1.00 7.54  ? 198 GLY A N   1 
ATOM 1554 C CA  . GLY A 1 214 ? 155.614 166.819 129.204 1.00 7.54  ? 198 GLY A CA  1 
ATOM 1555 C C   . GLY A 1 214 ? 156.866 166.585 128.383 1.00 7.54  ? 198 GLY A C   1 
ATOM 1556 O O   . GLY A 1 214 ? 157.882 167.255 128.588 1.00 7.54  ? 198 GLY A O   1 
ATOM 1557 N N   . VAL A 1 215 ? 156.806 165.630 127.461 1.00 7.87  ? 199 VAL A N   1 
ATOM 1558 C CA  . VAL A 1 215 ? 157.953 165.346 126.591 1.00 7.87  ? 199 VAL A CA  1 
ATOM 1559 C C   . VAL A 1 215 ? 158.276 166.581 125.759 1.00 7.87  ? 199 VAL A C   1 
ATOM 1560 O O   . VAL A 1 215 ? 157.358 167.195 125.180 1.00 7.87  ? 199 VAL A O   1 
ATOM 1561 C CB  . VAL A 1 215 ? 157.655 164.142 125.683 1.00 7.87  ? 199 VAL A CB  1 
ATOM 1562 C CG1 . VAL A 1 215 ? 158.919 163.674 124.984 1.00 7.87  ? 199 VAL A CG1 1 
ATOM 1563 C CG2 . VAL A 1 215 ? 157.040 163.017 126.486 1.00 7.87  ? 199 VAL A CG2 1 
ATOM 1564 N N   . PRO A 1 216 ? 159.538 166.997 125.667 1.00 9.97  ? 200 PRO A N   1 
ATOM 1565 C CA  . PRO A 1 216 ? 159.878 168.113 124.778 1.00 9.97  ? 200 PRO A CA  1 
ATOM 1566 C C   . PRO A 1 216 ? 159.672 167.738 123.318 1.00 9.97  ? 200 PRO A C   1 
ATOM 1567 O O   . PRO A 1 216 ? 159.767 166.571 122.932 1.00 9.97  ? 200 PRO A O   1 
ATOM 1568 C CB  . PRO A 1 216 ? 161.356 168.381 125.088 1.00 9.97  ? 200 PRO A CB  1 
ATOM 1569 C CG  . PRO A 1 216 ? 161.860 167.114 125.682 1.00 9.97  ? 200 PRO A CG  1 
ATOM 1570 C CD  . PRO A 1 216 ? 160.705 166.509 126.419 1.00 9.97  ? 200 PRO A CD  1 
ATOM 1571 N N   . CYS A 1 217 ? 159.384 168.755 122.503 1.00 12.22 ? 201 CYS A N   1 
ATOM 1572 C CA  . CYS A 1 217 ? 159.061 168.532 121.098 1.00 12.22 ? 201 CYS A CA  1 
ATOM 1573 C C   . CYS A 1 217 ? 160.241 167.988 120.301 1.00 12.22 ? 201 CYS A C   1 
ATOM 1574 O O   . CYS A 1 217 ? 160.027 167.280 119.311 1.00 12.22 ? 201 CYS A O   1 
ATOM 1575 C CB  . CYS A 1 217 ? 158.557 169.837 120.475 1.00 12.22 ? 201 CYS A CB  1 
ATOM 1576 S SG  . CYS A 1 217 ? 158.789 169.995 118.688 1.00 12.22 ? 201 CYS A SG  1 
ATOM 1577 N N   . SER A 1 218 ? 161.473 168.275 120.719 1.00 10.74 ? 202 SER A N   1 
ATOM 1578 C CA  . SER A 1 218 ? 162.649 167.893 119.946 1.00 10.74 ? 202 SER A CA  1 
ATOM 1579 C C   . SER A 1 218 ? 162.908 166.391 119.936 1.00 10.74 ? 202 SER A C   1 
ATOM 1580 O O   . SER A 1 218 ? 163.680 165.923 119.093 1.00 10.74 ? 202 SER A O   1 
ATOM 1581 C CB  . SER A 1 218 ? 163.886 168.615 120.485 1.00 10.74 ? 202 SER A CB  1 
ATOM 1582 O OG  . SER A 1 218 ? 163.826 170.004 120.214 1.00 10.74 ? 202 SER A OG  1 
ATOM 1583 N N   . GLN A 1 219 ? 162.290 165.629 120.835 1.00 9.69  ? 203 GLN A N   1 
ATOM 1584 C CA  . GLN A 1 219 ? 162.529 164.195 120.932 1.00 9.69  ? 203 GLN A CA  1 
ATOM 1585 C C   . GLN A 1 219 ? 161.542 163.363 120.123 1.00 9.69  ? 203 GLN A C   1 
ATOM 1586 O O   . GLN A 1 219 ? 161.608 162.130 120.180 1.00 9.69  ? 203 GLN A O   1 
ATOM 1587 C CB  . GLN A 1 219 ? 162.490 163.751 122.397 1.00 9.69  ? 203 GLN A CB  1 
ATOM 1588 C CG  . GLN A 1 219 ? 163.233 164.675 123.347 1.00 9.69  ? 203 GLN A CG  1 
ATOM 1589 C CD  . GLN A 1 219 ? 164.732 164.678 123.115 1.00 9.69  ? 203 GLN A CD  1 
ATOM 1590 O OE1 . GLN A 1 219 ? 165.281 163.761 122.504 1.00 9.69  ? 203 GLN A OE1 1 
ATOM 1591 N NE2 . GLN A 1 219 ? 165.404 165.713 123.606 1.00 9.69  ? 203 GLN A NE2 1 
ATOM 1592 N N   . ASN A 1 220 ? 160.636 164.002 119.378 1.00 16.09 ? 204 ASN A N   1 
ATOM 1593 C CA  . ASN A 1 220 ? 159.630 163.329 118.562 1.00 16.09 ? 204 ASN A CA  1 
ATOM 1594 C C   . ASN A 1 220 ? 158.777 162.395 119.413 1.00 16.09 ? 204 ASN A C   1 
ATOM 1595 O O   . ASN A 1 220 ? 158.865 161.169 119.265 1.00 16.09 ? 204 ASN A O   1 
ATOM 1596 C CB  . ASN A 1 220 ? 160.288 162.550 117.421 1.00 16.09 ? 204 ASN A CB  1 
ATOM 1597 C CG  . ASN A 1 220 ? 160.997 163.452 116.433 1.00 16.09 ? 204 ASN A CG  1 
ATOM 1598 O OD1 . ASN A 1 220 ? 160.565 164.576 116.180 1.00 16.09 ? 204 ASN A OD1 1 
ATOM 1599 N ND2 . ASN A 1 220 ? 162.094 162.962 115.866 1.00 16.09 ? 204 ASN A ND2 1 
ATOM 1600 N N   . PRO A 1 221 ? 157.944 162.926 120.310 1.00 15.75 ? 205 PRO A N   1 
ATOM 1601 C CA  . PRO A 1 221 ? 157.124 162.051 121.157 1.00 15.75 ? 205 PRO A CA  1 
ATOM 1602 C C   . PRO A 1 221 ? 156.006 161.370 120.384 1.00 15.75 ? 205 PRO A C   1 
ATOM 1603 O O   . PRO A 1 221 ? 155.576 160.270 120.744 1.00 15.75 ? 205 PRO A O   1 
ATOM 1604 C CB  . PRO A 1 221 ? 156.575 163.011 122.216 1.00 15.75 ? 205 PRO A CB  1 
ATOM 1605 C CG  . PRO A 1 221 ? 156.504 164.320 121.517 1.00 15.75 ? 205 PRO A CG  1 
ATOM 1606 C CD  . PRO A 1 221 ? 157.656 164.352 120.544 1.00 15.75 ? 205 PRO A CD  1 
ATOM 1607 N N   . THR A 1 222 ? 155.528 162.014 119.319 1.00 19.11 ? 206 THR A N   1 
ATOM 1608 C CA  . THR A 1 222 ? 154.450 161.454 118.513 1.00 19.11 ? 206 THR A CA  1 
ATOM 1609 C C   . THR A 1 222 ? 154.911 160.316 117.614 1.00 19.11 ? 206 THR A C   1 
ATOM 1610 O O   . THR A 1 222 ? 154.064 159.622 117.040 1.00 19.11 ? 206 THR A O   1 
ATOM 1611 C CB  . THR A 1 222 ? 153.805 162.544 117.654 1.00 19.11 ? 206 THR A CB  1 
ATOM 1612 O OG1 . THR A 1 222 ? 152.790 161.963 116.827 1.00 19.11 ? 206 THR A OG1 1 
ATOM 1613 C CG2 . THR A 1 222 ? 154.848 163.210 116.771 1.00 19.11 ? 206 THR A CG2 1 
ATOM 1614 N N   . GLU A 1 223 ? 156.218 160.109 117.474 1.00 18.43 ? 207 GLU A N   1 
ATOM 1615 C CA  . GLU A 1 223 ? 156.747 159.020 116.665 1.00 18.43 ? 207 GLU A CA  1 
ATOM 1616 C C   . GLU A 1 223 ? 157.146 157.805 117.488 1.00 18.43 ? 207 GLU A C   1 
ATOM 1617 O O   . GLU A 1 223 ? 157.125 156.686 116.967 1.00 18.43 ? 207 GLU A O   1 
ATOM 1618 C CB  . GLU A 1 223 ? 157.957 159.501 115.858 1.00 18.43 ? 207 GLU A CB  1 
ATOM 1619 C CG  . GLU A 1 223 ? 157.852 159.236 114.367 1.00 18.43 ? 207 GLU A CG  1 
ATOM 1620 C CD  . GLU A 1 223 ? 158.757 160.139 113.554 1.00 18.43 ? 207 GLU A CD  1 
ATOM 1621 O OE1 . GLU A 1 223 ? 159.986 160.099 113.768 1.00 18.43 ? 207 GLU A OE1 1 
ATOM 1622 O OE2 . GLU A 1 223 ? 158.238 160.890 112.702 1.00 18.43 ? 207 GLU A OE2 1 
ATOM 1623 N N   . ALA A 1 224 ? 157.514 158.001 118.757 1.00 13.52 ? 208 ALA A N   1 
ATOM 1624 C CA  . ALA A 1 224 ? 157.832 156.867 119.618 1.00 13.52 ? 208 ALA A CA  1 
ATOM 1625 C C   . ALA A 1 224 ? 156.606 155.996 119.856 1.00 13.52 ? 208 ALA A C   1 
ATOM 1626 O O   . ALA A 1 224 ? 156.704 154.764 119.873 1.00 13.52 ? 208 ALA A O   1 
ATOM 1627 C CB  . ALA A 1 224 ? 158.408 157.360 120.945 1.00 13.52 ? 208 ALA A CB  1 
ATOM 1628 N N   . ILE A 1 225 ? 155.443 156.620 120.050 1.00 13.73 ? 209 ILE A N   1 
ATOM 1629 C CA  . ILE A 1 225 ? 154.211 155.862 120.253 1.00 13.73 ? 209 ILE A CA  1 
ATOM 1630 C C   . ILE A 1 225 ? 153.887 155.036 119.014 1.00 13.73 ? 209 ILE A C   1 
ATOM 1631 O O   . ILE A 1 225 ? 153.525 153.858 119.108 1.00 13.73 ? 209 ILE A O   1 
ATOM 1632 C CB  . ILE A 1 225 ? 153.054 156.808 120.617 1.00 13.73 ? 209 ILE A CB  1 
ATOM 1633 C CG1 . ILE A 1 225 ? 153.507 157.824 121.667 1.00 13.73 ? 209 ILE A CG1 1 
ATOM 1634 C CG2 . ILE A 1 225 ? 151.857 156.017 121.112 1.00 13.73 ? 209 ILE A CG2 1 
ATOM 1635 C CD1 . ILE A 1 225 ? 152.416 158.776 122.104 1.00 13.73 ? 209 ILE A CD1 1 
ATOM 1636 N N   . GLU A 1 226 ? 154.009 155.647 117.833 1.00 17.79 ? 210 GLU A N   1 
ATOM 1637 C CA  . GLU A 1 226 ? 153.712 154.935 116.594 1.00 17.79 ? 210 GLU A CA  1 
ATOM 1638 C C   . GLU A 1 226 ? 154.688 153.788 116.363 1.00 17.79 ? 210 GLU A C   1 
ATOM 1639 O O   . GLU A 1 226 ? 154.287 152.704 115.924 1.00 17.79 ? 210 GLU A O   1 
ATOM 1640 C CB  . GLU A 1 226 ? 153.732 155.906 115.414 1.00 17.79 ? 210 GLU A CB  1 
ATOM 1641 C CG  . GLU A 1 226 ? 153.400 155.264 114.078 1.00 17.79 ? 210 GLU A CG  1 
ATOM 1642 C CD  . GLU A 1 226 ? 153.422 156.258 112.934 1.00 17.79 ? 210 GLU A CD  1 
ATOM 1643 O OE1 . GLU A 1 226 ? 153.171 157.456 113.181 1.00 17.79 ? 210 GLU A OE1 1 
ATOM 1644 O OE2 . GLU A 1 226 ? 153.691 155.841 111.788 1.00 17.79 ? 210 GLU A OE2 1 
ATOM 1645 N N   . ALA A 1 227 ? 155.974 154.007 116.645 1.00 14.03 ? 211 ALA A N   1 
ATOM 1646 C CA  . ALA A 1 227 ? 156.959 152.946 116.476 1.00 14.03 ? 211 ALA A CA  1 
ATOM 1647 C C   . ALA A 1 227 ? 156.815 151.849 117.523 1.00 14.03 ? 211 ALA A C   1 
ATOM 1648 O O   . ALA A 1 227 ? 157.205 150.707 117.262 1.00 14.03 ? 211 ALA A O   1 
ATOM 1649 C CB  . ALA A 1 227 ? 158.372 153.527 116.522 1.00 14.03 ? 211 ALA A CB  1 
ATOM 1650 N N   . TRP A 1 228 ? 156.272 152.170 118.698 1.00 13.21 ? 212 TRP A N   1 
ATOM 1651 C CA  . TRP A 1 228 ? 156.129 151.170 119.750 1.00 13.21 ? 212 TRP A CA  1 
ATOM 1652 C C   . TRP A 1 228 ? 154.959 150.229 119.486 1.00 13.21 ? 212 TRP A C   1 
ATOM 1653 O O   . TRP A 1 228 ? 155.068 149.021 119.723 1.00 13.21 ? 212 TRP A O   1 
ATOM 1654 C CB  . TRP A 1 228 ? 155.955 151.859 121.102 1.00 13.21 ? 212 TRP A CB  1 
ATOM 1655 C CG  . TRP A 1 228 ? 155.678 150.917 122.228 1.00 13.21 ? 212 TRP A CG  1 
ATOM 1656 C CD1 . TRP A 1 228 ? 156.568 150.082 122.835 1.00 13.21 ? 212 TRP A CD1 1 
ATOM 1657 C CD2 . TRP A 1 228 ? 154.421 150.706 122.879 1.00 13.21 ? 212 TRP A CD2 1 
ATOM 1658 N NE1 . TRP A 1 228 ? 155.945 149.369 123.830 1.00 13.21 ? 212 TRP A NE1 1 
ATOM 1659 C CE2 . TRP A 1 228 ? 154.626 149.735 123.876 1.00 13.21 ? 212 TRP A CE2 1 
ATOM 1660 C CE3 . TRP A 1 228 ? 153.143 151.249 122.718 1.00 13.21 ? 212 TRP A CE3 1 
ATOM 1661 C CZ2 . TRP A 1 228 ? 153.602 149.294 124.709 1.00 13.21 ? 212 TRP A CZ2 1 
ATOM 1662 C CZ3 . TRP A 1 228 ? 152.128 150.810 123.545 1.00 13.21 ? 212 TRP A CZ3 1 
ATOM 1663 C CH2 . TRP A 1 228 ? 152.363 149.842 124.527 1.00 13.21 ? 212 TRP A CH2 1 
ATOM 1664 N N   . ILE A 1 229 ? 153.836 150.759 118.994 1.00 16.45 ? 213 ILE A N   1 
ATOM 1665 C CA  . ILE A 1 229 ? 152.635 149.949 118.813 1.00 16.45 ? 213 ILE A CA  1 
ATOM 1666 C C   . ILE A 1 229 ? 152.751 148.957 117.667 1.00 16.45 ? 213 ILE A C   1 
ATOM 1667 O O   . ILE A 1 229 ? 151.869 148.106 117.509 1.00 16.45 ? 213 ILE A O   1 
ATOM 1668 C CB  . ILE A 1 229 ? 151.396 150.842 118.591 1.00 16.45 ? 213 ILE A CB  1 
ATOM 1669 C CG1 . ILE A 1 229 ? 151.556 151.680 117.323 1.00 16.45 ? 213 ILE A CG1 1 
ATOM 1670 C CG2 . ILE A 1 229 ? 151.155 151.732 119.799 1.00 16.45 ? 213 ILE A CG2 1 
ATOM 1671 C CD1 . ILE A 1 229 ? 150.379 152.587 117.043 1.00 16.45 ? 213 ILE A CD1 1 
ATOM 1672 N N   . ASN A 1 230 ? 153.811 149.037 116.867 1.00 18.81 ? 214 ASN A N   1 
ATOM 1673 C CA  . ASN A 1 230 ? 154.016 148.110 115.762 1.00 18.81 ? 214 ASN A CA  1 
ATOM 1674 C C   . ASN A 1 230 ? 154.607 146.778 116.208 1.00 18.81 ? 214 ASN A C   1 
ATOM 1675 O O   . ASN A 1 230 ? 154.951 145.954 115.353 1.00 18.81 ? 214 ASN A O   1 
ATOM 1676 C CB  . ASN A 1 230 ? 154.917 148.747 114.702 1.00 18.81 ? 214 ASN A CB  1 
ATOM 1677 C CG  . ASN A 1 230 ? 154.341 150.032 114.145 1.00 18.81 ? 214 ASN A CG  1 
ATOM 1678 O OD1 . ASN A 1 230 ? 153.125 150.217 114.112 1.00 18.81 ? 214 ASN A OD1 1 
ATOM 1679 N ND2 . ASN A 1 230 ? 155.214 150.930 113.704 1.00 18.81 ? 214 ASN A ND2 1 
ATOM 1680 N N   . PHE A 1 231 ? 154.734 146.548 117.516 1.00 18.61 ? 215 PHE A N   1 
ATOM 1681 C CA  . PHE A 1 231 ? 155.300 145.295 118.001 1.00 18.61 ? 215 PHE A CA  1 
ATOM 1682 C C   . PHE A 1 231 ? 154.253 144.190 118.072 1.00 18.61 ? 215 PHE A C   1 
ATOM 1683 O O   . PHE A 1 231 ? 154.533 143.042 117.710 1.00 18.61 ? 215 PHE A O   1 
ATOM 1684 C CB  . PHE A 1 231 ? 155.941 145.508 119.372 1.00 18.61 ? 215 PHE A CB  1 
ATOM 1685 C CG  . PHE A 1 231 ? 157.184 144.698 119.592 1.00 18.61 ? 215 PHE A CG  1 
ATOM 1686 C CD1 . PHE A 1 231 ? 158.117 144.549 118.580 1.00 18.61 ? 215 PHE A CD1 1 
ATOM 1687 C CD2 . PHE A 1 231 ? 157.421 144.087 120.811 1.00 18.61 ? 215 PHE A CD2 1 
ATOM 1688 C CE1 . PHE A 1 231 ? 159.263 143.803 118.779 1.00 18.61 ? 215 PHE A CE1 1 
ATOM 1689 C CE2 . PHE A 1 231 ? 158.565 143.340 121.017 1.00 18.61 ? 215 PHE A CE2 1 
ATOM 1690 C CZ  . PHE A 1 231 ? 159.487 143.198 120.000 1.00 18.61 ? 215 PHE A CZ  1 
ATOM 1691 N N   . ASN A 1 232 ? 153.047 144.513 118.533 1.00 20.71 ? 216 ASN A N   1 
ATOM 1692 C CA  . ASN A 1 232 ? 151.979 143.532 118.710 1.00 20.71 ? 216 ASN A CA  1 
ATOM 1693 C C   . ASN A 1 232 ? 150.674 144.072 118.135 1.00 20.71 ? 216 ASN A C   1 
ATOM 1694 O O   . ASN A 1 232 ? 149.627 144.055 118.783 1.00 20.71 ? 216 ASN A O   1 
ATOM 1695 C CB  . ASN A 1 232 ? 151.818 143.155 120.181 1.00 20.71 ? 216 ASN A CB  1 
ATOM 1696 C CG  . ASN A 1 232 ? 152.737 142.025 120.597 1.00 20.71 ? 216 ASN A CG  1 
ATOM 1697 O OD1 . ASN A 1 232 ? 153.375 141.388 119.758 1.00 20.71 ? 216 ASN A OD1 1 
ATOM 1698 N ND2 . ASN A 1 232 ? 152.807 141.766 121.897 1.00 20.71 ? 216 ASN A ND2 1 
ATOM 1699 N N   . LYS A 1 233 ? 150.731 144.559 116.892 1.00 21.96 ? 217 LYS A N   1 
ATOM 1700 C CA  . LYS A 1 233 ? 149.571 145.157 116.236 1.00 21.96 ? 217 LYS A CA  1 
ATOM 1701 C C   . LYS A 1 233 ? 148.355 144.239 116.195 1.00 21.96 ? 217 LYS A C   1 
ATOM 1702 O O   . LYS A 1 233 ? 147.253 144.718 115.905 1.00 21.96 ? 217 LYS A O   1 
ATOM 1703 C CB  . LYS A 1 233 ? 149.934 145.578 114.811 1.00 21.96 ? 217 LYS A CB  1 
ATOM 1704 C CG  . LYS A 1 233 ? 150.649 146.916 114.717 1.00 21.96 ? 217 LYS A CG  1 
ATOM 1705 C CD  . LYS A 1 233 ? 150.650 147.447 113.290 1.00 21.96 ? 217 LYS A CD  1 
ATOM 1706 C CE  . LYS A 1 233 ? 149.239 147.584 112.730 1.00 21.96 ? 217 LYS A CE  1 
ATOM 1707 N NZ  . LYS A 1 233 ? 148.261 148.081 113.737 1.00 21.96 ? 217 LYS A NZ  1 
ATOM 1708 N N   . GLU A 1 234 ? 148.522 142.942 116.467 1.00 20.97 ? 218 GLU A N   1 
ATOM 1709 C CA  . GLU A 1 234 ? 147.372 142.045 116.513 1.00 20.97 ? 218 GLU A CA  1 
ATOM 1710 C C   . GLU A 1 234 ? 146.409 142.441 117.626 1.00 20.97 ? 218 GLU A C   1 
ATOM 1711 O O   . GLU A 1 234 ? 145.186 142.394 117.446 1.00 20.97 ? 218 GLU A O   1 
ATOM 1712 C CB  . GLU A 1 234 ? 147.841 140.602 116.696 1.00 20.97 ? 218 GLU A CB  1 
ATOM 1713 C CG  . GLU A 1 234 ? 146.715 139.580 116.716 1.00 20.97 ? 218 GLU A CG  1 
ATOM 1714 C CD  . GLU A 1 234 ? 147.221 138.155 116.616 1.00 20.97 ? 218 GLU A CD  1 
ATOM 1715 O OE1 . GLU A 1 234 ? 148.395 137.913 116.968 1.00 20.97 ? 218 GLU A OE1 1 
ATOM 1716 O OE2 . GLU A 1 234 ? 146.444 137.276 116.187 1.00 20.97 ? 218 GLU A OE2 1 
ATOM 1717 N N   . GLU A 1 235 ? 146.940 142.837 118.783 1.00 21.06 ? 219 GLU A N   1 
ATOM 1718 C CA  . GLU A 1 235 ? 146.114 143.234 119.917 1.00 21.06 ? 219 GLU A CA  1 
ATOM 1719 C C   . GLU A 1 235 ? 146.480 144.583 120.520 1.00 21.06 ? 219 GLU A C   1 
ATOM 1720 O O   . GLU A 1 235 ? 145.669 145.131 121.277 1.00 21.06 ? 219 GLU A O   1 
ATOM 1721 C CB  . GLU A 1 235 ? 146.177 142.173 121.026 1.00 21.06 ? 219 GLU A CB  1 
ATOM 1722 C CG  . GLU A 1 235 ? 145.621 140.817 120.624 1.00 21.06 ? 219 GLU A CG  1 
ATOM 1723 C CD  . GLU A 1 235 ? 145.675 139.808 121.755 1.00 21.06 ? 219 GLU A CD  1 
ATOM 1724 O OE1 . GLU A 1 235 ? 146.065 140.192 122.878 1.00 21.06 ? 219 GLU A OE1 1 
ATOM 1725 O OE2 . GLU A 1 235 ? 145.328 138.632 121.521 1.00 21.06 ? 219 GLU A OE2 1 
ATOM 1726 N N   . ARG A 1 236 ? 147.654 145.137 120.219 1.00 18.61 ? 220 ARG A N   1 
ATOM 1727 C CA  . ARG A 1 236 ? 148.081 146.390 120.830 1.00 18.61 ? 220 ARG A CA  1 
ATOM 1728 C C   . ARG A 1 236 ? 147.435 147.615 120.198 1.00 18.61 ? 220 ARG A C   1 
ATOM 1729 O O   . ARG A 1 236 ? 147.591 148.718 120.733 1.00 18.61 ? 220 ARG A O   1 
ATOM 1730 C CB  . ARG A 1 236 ? 149.604 146.519 120.750 1.00 18.61 ? 220 ARG A CB  1 
ATOM 1731 C CG  . ARG A 1 236 ? 150.313 146.318 122.077 1.00 18.61 ? 220 ARG A CG  1 
ATOM 1732 C CD  . ARG A 1 236 ? 151.728 146.866 122.035 1.00 18.61 ? 220 ARG A CD  1 
ATOM 1733 N NE  . ARG A 1 236 ? 152.387 146.767 123.331 1.00 18.61 ? 220 ARG A NE  1 
ATOM 1734 C CZ  . ARG A 1 236 ? 153.014 145.685 123.773 1.00 18.61 ? 220 ARG A CZ  1 
ATOM 1735 N NH1 . ARG A 1 236 ? 153.094 144.586 123.041 1.00 18.61 ? 220 ARG A NH1 1 
ATOM 1736 N NH2 . ARG A 1 236 ? 153.575 145.707 124.978 1.00 18.61 ? 220 ARG A NH2 1 
ATOM 1737 N N   . GLU A 1 237 ? 146.719 147.454 119.083 1.00 19.41 ? 221 GLU A N   1 
ATOM 1738 C CA  . GLU A 1 237 ? 146.100 148.595 118.418 1.00 19.41 ? 221 GLU A CA  1 
ATOM 1739 C C   . GLU A 1 237 ? 144.987 149.221 119.250 1.00 19.41 ? 221 GLU A C   1 
ATOM 1740 O O   . GLU A 1 237 ? 144.652 150.390 119.033 1.00 19.41 ? 221 GLU A O   1 
ATOM 1741 C CB  . GLU A 1 237 ? 145.560 148.170 117.050 1.00 19.41 ? 221 GLU A CB  1 
ATOM 1742 C CG  . GLU A 1 237 ? 145.134 149.324 116.154 1.00 19.41 ? 221 GLU A CG  1 
ATOM 1743 C CD  . GLU A 1 237 ? 146.315 150.069 115.564 1.00 19.41 ? 221 GLU A CD  1 
ATOM 1744 O OE1 . GLU A 1 237 ? 147.389 149.453 115.404 1.00 19.41 ? 221 GLU A OE1 1 
ATOM 1745 O OE2 . GLU A 1 237 ? 146.169 151.272 115.261 1.00 19.41 ? 221 GLU A OE2 1 
ATOM 1746 N N   . ALA A 1 238 ? 144.415 148.476 120.199 1.00 16.81 ? 222 ALA A N   1 
ATOM 1747 C CA  . ALA A 1 238 ? 143.355 149.029 121.036 1.00 16.81 ? 222 ALA A CA  1 
ATOM 1748 C C   . ALA A 1 238 ? 143.863 150.195 121.876 1.00 16.81 ? 222 ALA A C   1 
ATOM 1749 O O   . ALA A 1 238 ? 143.167 151.204 122.037 1.00 16.81 ? 222 ALA A O   1 
ATOM 1750 C CB  . ALA A 1 238 ? 142.767 147.938 121.929 1.00 16.81 ? 222 ALA A CB  1 
ATOM 1751 N N   . PHE A 1 239 ? 145.075 150.076 122.418 1.00 17.19 ? 223 PHE A N   1 
ATOM 1752 C CA  . PHE A 1 239 ? 145.649 151.127 123.248 1.00 17.19 ? 223 PHE A CA  1 
ATOM 1753 C C   . PHE A 1 239 ? 146.215 152.287 122.439 1.00 17.19 ? 223 PHE A C   1 
ATOM 1754 O O   . PHE A 1 239 ? 146.575 153.310 123.031 1.00 17.19 ? 223 PHE A O   1 
ATOM 1755 C CB  . PHE A 1 239 ? 146.752 150.552 124.139 1.00 17.19 ? 223 PHE A CB  1 
ATOM 1756 C CG  . PHE A 1 239 ? 146.299 149.420 125.013 1.00 17.19 ? 223 PHE A CG  1 
ATOM 1757 C CD1 . PHE A 1 239 ? 145.051 149.444 125.611 1.00 17.19 ? 223 PHE A CD1 1 
ATOM 1758 C CD2 . PHE A 1 239 ? 147.124 148.331 125.238 1.00 17.19 ? 223 PHE A CD2 1 
ATOM 1759 C CE1 . PHE A 1 239 ? 144.633 148.403 126.418 1.00 17.19 ? 223 PHE A CE1 1 
ATOM 1760 C CE2 . PHE A 1 239 ? 146.712 147.286 126.043 1.00 17.19 ? 223 PHE A CE2 1 
ATOM 1761 C CZ  . PHE A 1 239 ? 145.465 147.322 126.634 1.00 17.19 ? 223 PHE A CZ  1 
ATOM 1762 N N   . ALA A 1 240 ? 146.307 152.153 121.114 1.00 15.42 ? 224 ALA A N   1 
ATOM 1763 C CA  . ALA A 1 240 ? 146.925 153.198 120.304 1.00 15.42 ? 224 ALA A CA  1 
ATOM 1764 C C   . ALA A 1 240 ? 146.141 154.502 120.377 1.00 15.42 ? 224 ALA A C   1 
ATOM 1765 O O   . ALA A 1 240 ? 146.730 155.583 120.490 1.00 15.42 ? 224 ALA A O   1 
ATOM 1766 C CB  . ALA A 1 240 ? 147.054 152.730 118.855 1.00 15.42 ? 224 ALA A CB  1 
ATOM 1767 N N   . GLU A 1 241 ? 144.810 154.423 120.309 1.00 15.88 ? 225 GLU A N   1 
ATOM 1768 C CA  . GLU A 1 241 ? 143.999 155.637 120.328 1.00 15.88 ? 225 GLU A CA  1 
ATOM 1769 C C   . GLU A 1 241 ? 144.077 156.340 121.678 1.00 15.88 ? 225 GLU A C   1 
ATOM 1770 O O   . GLU A 1 241 ? 144.102 157.574 121.740 1.00 15.88 ? 225 GLU A O   1 
ATOM 1771 C CB  . GLU A 1 241 ? 142.549 155.306 119.978 1.00 15.88 ? 225 GLU A CB  1 
ATOM 1772 C CG  . GLU A 1 241 ? 141.727 156.514 119.557 1.00 15.88 ? 225 GLU A CG  1 
ATOM 1773 C CD  . GLU A 1 241 ? 142.257 157.172 118.297 1.00 15.88 ? 225 GLU A CD  1 
ATOM 1774 O OE1 . GLU A 1 241 ? 142.795 156.454 117.428 1.00 15.88 ? 225 GLU A OE1 1 
ATOM 1775 O OE2 . GLU A 1 241 ? 142.138 158.410 118.177 1.00 15.88 ? 225 GLU A OE2 1 
ATOM 1776 N N   . SER A 1 242 ? 144.111 155.573 122.770 1.00 13.43 ? 226 SER A N   1 
ATOM 1777 C CA  . SER A 1 242 ? 144.165 156.180 124.095 1.00 13.43 ? 226 SER A CA  1 
ATOM 1778 C C   . SER A 1 242 ? 145.498 156.872 124.348 1.00 13.43 ? 226 SER A C   1 
ATOM 1779 O O   . SER A 1 242 ? 145.538 157.902 125.031 1.00 13.43 ? 226 SER A O   1 
ATOM 1780 C CB  . SER A 1 242 ? 143.906 155.124 125.168 1.00 13.43 ? 226 SER A CB  1 
ATOM 1781 O OG  . SER A 1 242 ? 144.367 155.562 126.435 1.00 13.43 ? 226 SER A OG  1 
ATOM 1782 N N   . LEU A 1 243 ? 146.594 156.323 123.818 1.00 13.63 ? 227 LEU A N   1 
ATOM 1783 C CA  . LEU A 1 243 ? 147.909 156.908 124.062 1.00 13.63 ? 227 LEU A CA  1 
ATOM 1784 C C   . LEU A 1 243 ? 148.044 158.292 123.439 1.00 13.63 ? 227 LEU A C   1 
ATOM 1785 O O   . LEU A 1 243 ? 148.611 159.196 124.063 1.00 13.63 ? 227 LEU A O   1 
ATOM 1786 C CB  . LEU A 1 243 ? 149.001 155.979 123.535 1.00 13.63 ? 227 LEU A CB  1 
ATOM 1787 C CG  . LEU A 1 243 ? 149.462 154.900 124.515 1.00 13.63 ? 227 LEU A CG  1 
ATOM 1788 C CD1 . LEU A 1 243 ? 150.550 154.038 123.900 1.00 13.63 ? 227 LEU A CD1 1 
ATOM 1789 C CD2 . LEU A 1 243 ? 149.942 155.532 125.810 1.00 13.63 ? 227 LEU A CD2 1 
ATOM 1790 N N   . ARG A 1 244 ? 147.533 158.480 122.220 1.00 16.50 ? 228 ARG A N   1 
ATOM 1791 C CA  . ARG A 1 244 ? 147.638 159.774 121.557 1.00 16.50 ? 228 ARG A CA  1 
ATOM 1792 C C   . ARG A 1 244 ? 146.787 160.848 122.220 1.00 16.50 ? 228 ARG A C   1 
ATOM 1793 O O   . ARG A 1 244 ? 147.013 162.038 121.971 1.00 16.50 ? 228 ARG A O   1 
ATOM 1794 C CB  . ARG A 1 244 ? 147.250 159.646 120.083 1.00 16.50 ? 228 ARG A CB  1 
ATOM 1795 C CG  . ARG A 1 244 ? 148.190 158.769 119.274 1.00 16.50 ? 228 ARG A CG  1 
ATOM 1796 C CD  . ARG A 1 244 ? 147.898 158.867 117.787 1.00 16.50 ? 228 ARG A CD  1 
ATOM 1797 N NE  . ARG A 1 244 ? 148.765 157.996 117.003 1.00 16.50 ? 228 ARG A NE  1 
ATOM 1798 C CZ  . ARG A 1 244 ? 148.348 156.930 116.334 1.00 16.50 ? 228 ARG A CZ  1 
ATOM 1799 N NH1 . ARG A 1 244 ? 147.075 156.570 116.331 1.00 16.50 ? 228 ARG A NH1 1 
ATOM 1800 N NH2 . ARG A 1 244 ? 149.231 156.206 115.652 1.00 16.50 ? 228 ARG A NH2 1 
ATOM 1801 N N   . THR A 1 245 ? 145.814 160.461 123.047 1.00 15.02 ? 229 THR A N   1 
ATOM 1802 C CA  . THR A 1 245 ? 145.024 161.433 123.791 1.00 15.02 ? 229 THR A CA  1 
ATOM 1803 C C   . THR A 1 245 ? 145.862 162.228 124.785 1.00 15.02 ? 229 THR A C   1 
ATOM 1804 O O   . THR A 1 245 ? 145.694 163.450 124.873 1.00 15.02 ? 229 THR A O   1 
ATOM 1805 C CB  . THR A 1 245 ? 143.877 160.723 124.519 1.00 15.02 ? 229 THR A CB  1 
ATOM 1806 O OG1 . THR A 1 245 ? 142.808 160.472 123.597 1.00 15.02 ? 229 THR A OG1 1 
ATOM 1807 C CG2 . THR A 1 245 ? 143.352 161.565 125.674 1.00 15.02 ? 229 THR A CG2 1 
ATOM 1808 N N   . SER A 1 246 ? 146.772 161.576 125.509 1.00 14.80 ? 230 SER A N   1 
ATOM 1809 C CA  . SER A 1 246 ? 147.628 162.227 126.502 1.00 14.80 ? 230 SER A CA  1 
ATOM 1810 C C   . SER A 1 246 ? 149.042 162.289 125.933 1.00 14.80 ? 230 SER A C   1 
ATOM 1811 O O   . SER A 1 246 ? 149.854 161.389 126.163 1.00 14.80 ? 230 SER A O   1 
ATOM 1812 C CB  . SER A 1 246 ? 147.584 161.482 127.833 1.00 14.80 ? 230 SER A CB  1 
ATOM 1813 O OG  . SER A 1 246 ? 148.310 162.177 128.831 1.00 14.80 ? 230 SER A OG  1 
ATOM 1814 N N   . LEU A 1 247 ? 149.332 163.354 125.187 1.00 13.99 ? 231 LEU A N   1 
ATOM 1815 C CA  . LEU A 1 247 ? 150.644 163.563 124.584 1.00 13.99 ? 231 LEU A CA  1 
ATOM 1816 C C   . LEU A 1 247 ? 151.066 165.019 124.784 1.00 13.99 ? 231 LEU A C   1 
ATOM 1817 O O   . LEU A 1 247 ? 151.441 165.723 123.841 1.00 13.99 ? 231 LEU A O   1 
ATOM 1818 C CB  . LEU A 1 247 ? 150.629 163.140 123.109 1.00 13.99 ? 231 LEU A CB  1 
ATOM 1819 C CG  . LEU A 1 247 ? 151.655 163.509 122.029 1.00 13.99 ? 231 LEU A CG  1 
ATOM 1820 C CD1 . LEU A 1 247 ? 152.952 162.750 122.238 1.00 13.99 ? 231 LEU A CD1 1 
ATOM 1821 C CD2 . LEU A 1 247 ? 151.091 163.251 120.640 1.00 13.99 ? 231 LEU A CD2 1 
ATOM 1822 N N   . LYS A 1 248 ? 150.968 165.500 126.021 1.00 13.99 ? 232 LYS A N   1 
ATOM 1823 C CA  . LYS A 1 248 ? 151.295 166.888 126.321 1.00 13.99 ? 232 LYS A CA  1 
ATOM 1824 C C   . LYS A 1 248 ? 152.754 167.178 125.993 1.00 13.99 ? 232 LYS A C   1 
ATOM 1825 O O   . LYS A 1 248 ? 153.662 166.577 126.575 1.00 13.99 ? 232 LYS A O   1 
ATOM 1826 C CB  . LYS A 1 248 ? 151.006 167.188 127.790 1.00 13.99 ? 232 LYS A CB  1 
ATOM 1827 C CG  . LYS A 1 248 ? 149.870 166.364 128.372 1.00 13.99 ? 232 LYS A CG  1 
ATOM 1828 C CD  . LYS A 1 248 ? 148.519 166.920 127.957 1.00 13.99 ? 232 LYS A CD  1 
ATOM 1829 C CE  . LYS A 1 248 ? 147.392 165.976 128.342 1.00 13.99 ? 232 LYS A CE  1 
ATOM 1830 N NZ  . LYS A 1 248 ? 147.452 165.594 129.779 1.00 13.99 ? 232 LYS A NZ  1 
ATOM 1831 N N   . GLU A 1 249 ? 152.974 168.098 125.059 1.00 17.15 ? 233 GLU A N   1 
ATOM 1832 C CA  . GLU A 1 249 ? 154.309 168.482 124.622 1.00 17.15 ? 233 GLU A CA  1 
ATOM 1833 C C   . GLU A 1 249 ? 154.615 169.892 125.103 1.00 17.15 ? 233 GLU A C   1 
ATOM 1834 O O   . GLU A 1 249 ? 153.839 170.820 124.853 1.00 17.15 ? 233 GLU A O   1 
ATOM 1835 C CB  . GLU A 1 249 ? 154.430 168.411 123.098 1.00 17.15 ? 233 GLU A CB  1 
ATOM 1836 C CG  . GLU A 1 249 ? 154.146 167.040 122.510 1.00 17.15 ? 233 GLU A CG  1 
ATOM 1837 C CD  . GLU A 1 249 ? 154.193 167.039 120.995 1.00 17.15 ? 233 GLU A CD  1 
ATOM 1838 O OE1 . GLU A 1 249 ? 154.498 168.099 120.408 1.00 17.15 ? 233 GLU A OE1 1 
ATOM 1839 O OE2 . GLU A 1 249 ? 153.924 165.981 120.390 1.00 17.15 ? 233 GLU A OE2 1 
ATOM 1840 N N   . ILE A 1 250 ? 155.738 170.048 125.786 1.00 14.43 ? 234 ILE A N   1 
ATOM 1841 C CA  . ILE A 1 250 ? 156.192 171.349 126.259 1.00 14.43 ? 234 ILE A CA  1 
ATOM 1842 C C   . ILE A 1 250 ? 157.208 171.896 125.269 1.00 14.43 ? 234 ILE A C   1 
ATOM 1843 O O   . ILE A 1 250 ? 158.036 171.159 124.724 1.00 14.43 ? 234 ILE A O   1 
ATOM 1844 C CB  . ILE A 1 250 ? 156.782 171.250 127.681 1.00 14.43 ? 234 ILE A CB  1 
ATOM 1845 C CG1 . ILE A 1 250 ? 155.830 170.484 128.601 1.00 14.43 ? 234 ILE A CG1 1 
ATOM 1846 C CG2 . ILE A 1 250 ? 157.061 172.635 128.243 1.00 14.43 ? 234 ILE A CG2 1 
ATOM 1847 C CD1 . ILE A 1 250 ? 156.270 170.454 130.049 1.00 14.43 ? 234 ILE A CD1 1 
ATOM 1848 N N   . GLY A 1 251 ? 157.143 173.201 125.027 1.00 13.51 ? 235 GLY A N   1 
ATOM 1849 C CA  . GLY A 1 251 ? 158.042 173.826 124.083 1.00 13.51 ? 235 GLY A CA  1 
ATOM 1850 C C   . GLY A 1 251 ? 159.484 173.786 124.547 1.00 13.51 ? 235 GLY A C   1 
ATOM 1851 O O   . GLY A 1 251 ? 159.798 173.609 125.725 1.00 13.51 ? 235 GLY A O   1 
ATOM 1852 N N   . GLU A 1 252 ? 160.383 173.954 123.583 1.00 15.16 ? 236 GLU A N   1 
ATOM 1853 C CA  . GLU A 1 252 ? 161.807 173.889 123.864 1.00 15.16 ? 236 GLU A CA  1 
ATOM 1854 C C   . GLU A 1 252 ? 162.294 175.179 124.513 1.00 15.16 ? 236 GLU A C   1 
ATOM 1855 O O   . GLU A 1 252 ? 162.025 176.284 124.035 1.00 15.16 ? 236 GLU A O   1 
ATOM 1856 C CB  . GLU A 1 252 ? 162.596 173.624 122.582 1.00 15.16 ? 236 GLU A CB  1 
ATOM 1857 C CG  . GLU A 1 252 ? 164.100 173.774 122.739 1.00 15.16 ? 236 GLU A CG  1 
ATOM 1858 C CD  . GLU A 1 252 ? 164.784 172.467 123.085 1.00 15.16 ? 236 GLU A CD  1 
ATOM 1859 O OE1 . GLU A 1 252 ? 165.926 172.508 123.587 1.00 15.16 ? 236 GLU A OE1 1 
ATOM 1860 O OE2 . GLU A 1 252 ? 164.179 171.399 122.854 1.00 15.16 ? 236 GLU A OE2 1 
ATOM 1861 N N   . ASN A 1 253 ? 163.016 175.024 125.617 1.00 14.03 ? 237 ASN A N   1 
ATOM 1862 C CA  . ASN A 1 253 ? 163.656 176.129 126.311 1.00 14.03 ? 237 ASN A CA  1 
ATOM 1863 C C   . ASN A 1 253 ? 165.125 176.200 125.915 1.00 14.03 ? 237 ASN A C   1 
ATOM 1864 O O   . ASN A 1 253 ? 165.686 175.265 125.338 1.00 14.03 ? 237 ASN A O   1 
ATOM 1865 C CB  . ASN A 1 253 ? 163.522 175.972 127.830 1.00 14.03 ? 237 ASN A CB  1 
ATOM 1866 C CG  . ASN A 1 253 ? 162.148 176.357 128.336 1.00 14.03 ? 237 ASN A CG  1 
ATOM 1867 O OD1 . ASN A 1 253 ? 161.267 175.510 128.480 1.00 14.03 ? 237 ASN A OD1 1 
ATOM 1868 N ND2 . ASN A 1 253 ? 161.957 177.642 128.611 1.00 14.03 ? 237 ASN A ND2 1 
ATOM 1869 N N   . VAL A 1 254 ? 165.746 177.331 126.231 1.00 11.49 ? 238 VAL A N   1 
ATOM 1870 C CA  . VAL A 1 254 ? 167.173 177.531 126.015 1.00 11.49 ? 238 VAL A CA  1 
ATOM 1871 C C   . VAL A 1 254 ? 167.887 177.339 127.346 1.00 11.49 ? 238 VAL A C   1 
ATOM 1872 O O   . VAL A 1 254 ? 167.359 177.704 128.404 1.00 11.49 ? 238 VAL A O   1 
ATOM 1873 C CB  . VAL A 1 254 ? 167.461 178.913 125.404 1.00 11.49 ? 238 VAL A CB  1 
ATOM 1874 C CG1 . VAL A 1 254 ? 166.682 179.078 124.113 1.00 11.49 ? 238 VAL A CG1 1 
ATOM 1875 C CG2 . VAL A 1 254 ? 167.079 180.006 126.365 1.00 11.49 ? 238 VAL A CG2 1 
ATOM 1876 N N   . HIS A 1 255 ? 169.077 176.741 127.298 1.00 8.91  ? 239 HIS A N   1 
ATOM 1877 C CA  . HIS A 1 255 ? 169.690 176.212 128.511 1.00 8.91  ? 239 HIS A CA  1 
ATOM 1878 C C   . HIS A 1 255 ? 170.520 177.264 129.240 1.00 8.91  ? 239 HIS A C   1 
ATOM 1879 O O   . HIS A 1 255 ? 170.246 177.589 130.400 1.00 8.91  ? 239 HIS A O   1 
ATOM 1880 C CB  . HIS A 1 255 ? 170.541 174.989 128.165 1.00 8.91  ? 239 HIS A CB  1 
ATOM 1881 C CG  . HIS A 1 255 ? 169.766 173.883 127.519 1.00 8.91  ? 239 HIS A CG  1 
ATOM 1882 N ND1 . HIS A 1 255 ? 170.174 173.269 126.355 1.00 8.91  ? 239 HIS A ND1 1 
ATOM 1883 C CD2 . HIS A 1 255 ? 168.603 173.288 127.871 1.00 8.91  ? 239 HIS A CD2 1 
ATOM 1884 C CE1 . HIS A 1 255 ? 169.298 172.339 126.021 1.00 8.91  ? 239 HIS A CE1 1 
ATOM 1885 N NE2 . HIS A 1 255 ? 168.334 172.330 126.924 1.00 8.91  ? 239 HIS A NE2 1 
ATOM 1886 N N   . ILE A 1 256 ? 171.539 177.806 128.581 1.00 5.40  ? 240 ILE A N   1 
ATOM 1887 C CA  . ILE A 1 256 ? 172.485 178.720 129.212 1.00 5.40  ? 240 ILE A CA  1 
ATOM 1888 C C   . ILE A 1 256 ? 172.298 180.102 128.606 1.00 5.40  ? 240 ILE A C   1 
ATOM 1889 O O   . ILE A 1 256 ? 172.390 180.269 127.383 1.00 5.40  ? 240 ILE A O   1 
ATOM 1890 C CB  . ILE A 1 256 ? 173.934 178.240 129.043 1.00 5.40  ? 240 ILE A CB  1 
ATOM 1891 C CG1 . ILE A 1 256 ? 174.013 176.719 129.160 1.00 5.40  ? 240 ILE A CG1 1 
ATOM 1892 C CG2 . ILE A 1 256 ? 174.828 178.892 130.078 1.00 5.40  ? 240 ILE A CG2 1 
ATOM 1893 C CD1 . ILE A 1 256 ? 175.413 176.174 129.002 1.00 5.40  ? 240 ILE A CD1 1 
ATOM 1894 N N   . TYR A 1 257 ? 172.043 181.094 129.459 1.00 5.87  ? 241 TYR A N   1 
ATOM 1895 C CA  . TYR A 1 257 ? 171.903 182.481 129.022 1.00 5.87  ? 241 TYR A CA  1 
ATOM 1896 C C   . TYR A 1 257 ? 173.240 183.180 129.242 1.00 5.87  ? 241 TYR A C   1 
ATOM 1897 O O   . TYR A 1 257 ? 173.418 183.971 130.167 1.00 5.87  ? 241 TYR A O   1 
ATOM 1898 C CB  . TYR A 1 257 ? 170.783 183.187 129.777 1.00 5.87  ? 241 TYR A CB  1 
ATOM 1899 C CG  . TYR A 1 257 ? 169.454 183.188 129.067 1.00 5.87  ? 241 TYR A CG  1 
ATOM 1900 C CD1 . TYR A 1 257 ? 169.171 184.126 128.086 1.00 5.87  ? 241 TYR A CD1 1 
ATOM 1901 C CD2 . TYR A 1 257 ? 168.461 182.288 129.419 1.00 5.87  ? 241 TYR A CD2 1 
ATOM 1902 C CE1 . TYR A 1 257 ? 167.951 184.140 127.446 1.00 5.87  ? 241 TYR A CE1 1 
ATOM 1903 C CE2 . TYR A 1 257 ? 167.237 182.301 128.793 1.00 5.87  ? 241 TYR A CE2 1 
ATOM 1904 C CZ  . TYR A 1 257 ? 166.987 183.225 127.804 1.00 5.87  ? 241 TYR A CZ  1 
ATOM 1905 O OH  . TYR A 1 257 ? 165.766 183.237 127.173 1.00 5.87  ? 241 TYR A OH  1 
ATOM 1906 N N   . LEU A 1 258 ? 174.192 182.878 128.369 1.00 4.47  ? 242 LEU A N   1 
ATOM 1907 C CA  . LEU A 1 258 ? 175.521 183.460 128.486 1.00 4.47  ? 242 LEU A CA  1 
ATOM 1908 C C   . LEU A 1 258 ? 175.459 184.926 128.073 1.00 4.47  ? 242 LEU A C   1 
ATOM 1909 O O   . LEU A 1 258 ? 175.354 185.238 126.884 1.00 4.47  ? 242 LEU A O   1 
ATOM 1910 C CB  . LEU A 1 258 ? 176.504 182.678 127.617 1.00 4.47  ? 242 LEU A CB  1 
ATOM 1911 C CG  . LEU A 1 258 ? 178.015 182.814 127.818 1.00 4.47  ? 242 LEU A CG  1 
ATOM 1912 C CD1 . LEU A 1 258 ? 178.730 181.717 127.049 1.00 4.47  ? 242 LEU A CD1 1 
ATOM 1913 C CD2 . LEU A 1 258 ? 178.542 184.171 127.404 1.00 4.47  ? 242 LEU A CD2 1 
ATOM 1914 N N   . ILE A 1 259 ? 175.528 185.825 129.049 1.00 4.23  ? 243 ILE A N   1 
ATOM 1915 C CA  . ILE A 1 259 ? 175.400 187.259 128.810 1.00 4.23  ? 243 ILE A CA  1 
ATOM 1916 C C   . ILE A 1 259 ? 176.811 187.829 128.733 1.00 4.23  ? 243 ILE A C   1 
ATOM 1917 O O   . ILE A 1 259 ? 177.505 187.955 129.748 1.00 4.23  ? 243 ILE A O   1 
ATOM 1918 C CB  . ILE A 1 259 ? 174.560 187.950 129.891 1.00 4.23  ? 243 ILE A CB  1 
ATOM 1919 C CG1 . ILE A 1 259 ? 174.767 189.466 129.854 1.00 4.23  ? 243 ILE A CG1 1 
ATOM 1920 C CG2 . ILE A 1 259 ? 174.864 187.381 131.271 1.00 4.23  ? 243 ILE A CG2 1 
ATOM 1921 C CD1 . ILE A 1 259 ? 173.884 190.223 130.819 1.00 4.23  ? 243 ILE A CD1 1 
ATOM 1922 N N   . GLY A 1 260 ? 177.245 188.168 127.522 1.00 8.80  ? 244 GLY A N   1 
ATOM 1923 C CA  . GLY A 1 260 ? 178.585 188.677 127.306 1.00 8.80  ? 244 GLY A CA  1 
ATOM 1924 C C   . GLY A 1 260 ? 178.727 190.161 127.567 1.00 8.80  ? 244 GLY A C   1 
ATOM 1925 O O   . GLY A 1 260 ? 178.047 190.977 126.938 1.00 8.80  ? 244 GLY A O   1 
ATOM 1926 N N   . LYS A 1 261 ? 179.612 190.525 128.495 1.00 13.03 ? 245 LYS A N   1 
ATOM 1927 C CA  . LYS A 1 261 ? 179.859 191.926 128.833 1.00 13.03 ? 245 LYS A CA  1 
ATOM 1928 C C   . LYS A 1 261 ? 181.141 192.380 128.140 1.00 13.03 ? 245 LYS A C   1 
ATOM 1929 O O   . LYS A 1 261 ? 182.227 192.396 128.720 1.00 13.03 ? 245 LYS A O   1 
ATOM 1930 C CB  . LYS A 1 261 ? 179.937 192.109 130.345 1.00 13.03 ? 245 LYS A CB  1 
ATOM 1931 C CG  . LYS A 1 261 ? 178.588 192.234 131.030 1.00 13.03 ? 245 LYS A CG  1 
ATOM 1932 C CD  . LYS A 1 261 ? 178.747 192.355 132.536 1.00 13.03 ? 245 LYS A CD  1 
ATOM 1933 C CE  . LYS A 1 261 ? 179.643 193.524 132.906 1.00 13.03 ? 245 LYS A CE  1 
ATOM 1934 N NZ  . LYS A 1 261 ? 179.812 193.645 134.380 1.00 13.03 ? 245 LYS A NZ  1 
ATOM 1935 N N   . GLU A 1 262 ? 181.004 192.754 126.871 1.00 20.54 ? 246 GLU A N   1 
ATOM 1936 C CA  . GLU A 1 262 ? 182.132 193.308 126.135 1.00 20.54 ? 246 GLU A CA  1 
ATOM 1937 C C   . GLU A 1 262 ? 182.446 194.713 126.634 1.00 20.54 ? 246 GLU A C   1 
ATOM 1938 O O   . GLU A 1 262 ? 181.538 195.510 126.892 1.00 20.54 ? 246 GLU A O   1 
ATOM 1939 C CB  . GLU A 1 262 ? 181.832 193.332 124.637 1.00 20.54 ? 246 GLU A CB  1 
ATOM 1940 C CG  . GLU A 1 262 ? 181.732 191.959 123.997 1.00 20.54 ? 246 GLU A CG  1 
ATOM 1941 C CD  . GLU A 1 262 ? 181.528 192.034 122.497 1.00 20.54 ? 246 GLU A CD  1 
ATOM 1942 O OE1 . GLU A 1 262 ? 181.176 193.124 121.999 1.00 20.54 ? 246 GLU A OE1 1 
ATOM 1943 O OE2 . GLU A 1 262 ? 181.721 191.006 121.815 1.00 20.54 ? 246 GLU A OE2 1 
ATOM 1944 N N   . SER A 1 263 ? 183.736 195.017 126.771 1.00 18.69 ? 247 SER A N   1 
ATOM 1945 C CA  . SER A 1 263 ? 184.165 196.336 127.219 1.00 18.69 ? 247 SER A CA  1 
ATOM 1946 C C   . SER A 1 263 ? 184.610 197.231 126.072 1.00 18.69 ? 247 SER A C   1 
ATOM 1947 O O   . SER A 1 263 ? 184.519 198.459 126.185 1.00 18.69 ? 247 SER A O   1 
ATOM 1948 C CB  . SER A 1 263 ? 185.304 196.205 128.234 1.00 18.69 ? 247 SER A CB  1 
ATOM 1949 O OG  . SER A 1 263 ? 185.566 197.445 128.868 1.00 18.69 ? 247 SER A OG  1 
ATOM 1950 N N   . SER A 1 264 ? 185.097 196.646 124.974 1.00 18.19 ? 248 SER A N   1 
ATOM 1951 C CA  . SER A 1 264 ? 185.501 197.447 123.823 1.00 18.19 ? 248 SER A CA  1 
ATOM 1952 C C   . SER A 1 264 ? 184.309 198.182 123.223 1.00 18.19 ? 248 SER A C   1 
ATOM 1953 O O   . SER A 1 264 ? 184.406 199.360 122.860 1.00 18.19 ? 248 SER A O   1 
ATOM 1954 C CB  . SER A 1 264 ? 186.173 196.557 122.776 1.00 18.19 ? 248 SER A CB  1 
ATOM 1955 O OG  . SER A 1 264 ? 185.361 195.439 122.463 1.00 18.19 ? 248 SER A OG  1 
ATOM 1956 N N   . ARG A 1 265 ? 183.173 197.500 123.111 1.00 21.89 ? 249 ARG A N   1 
ATOM 1957 C CA  . ARG A 1 265 ? 181.937 198.090 122.617 1.00 21.89 ? 249 ARG A CA  1 
ATOM 1958 C C   . ARG A 1 265 ? 180.909 198.098 123.739 1.00 21.89 ? 249 ARG A C   1 
ATOM 1959 O O   . ARG A 1 265 ? 180.710 197.080 124.411 1.00 21.89 ? 249 ARG A O   1 
ATOM 1960 C CB  . ARG A 1 265 ? 181.404 197.319 121.408 1.00 21.89 ? 249 ARG A CB  1 
ATOM 1961 C CG  . ARG A 1 265 ? 182.303 197.387 120.184 1.00 21.89 ? 249 ARG A CG  1 
ATOM 1962 C CD  . ARG A 1 265 ? 182.593 196.002 119.630 1.00 21.89 ? 249 ARG A CD  1 
ATOM 1963 N NE  . ARG A 1 265 ? 183.300 195.164 120.590 1.00 21.89 ? 249 ARG A NE  1 
ATOM 1964 C CZ  . ARG A 1 265 ? 183.727 193.933 120.340 1.00 21.89 ? 249 ARG A CZ  1 
ATOM 1965 N NH1 . ARG A 1 265 ? 183.538 193.363 119.161 1.00 21.89 ? 249 ARG A NH1 1 
ATOM 1966 N NH2 . ARG A 1 265 ? 184.358 193.258 121.296 1.00 21.89 ? 249 ARG A NH2 1 
ATOM 1967 N N   . THR A 1 266 ? 180.257 199.242 123.937 1.00 21.41 ? 250 THR A N   1 
ATOM 1968 C CA  . THR A 1 266 ? 179.294 199.387 125.021 1.00 21.41 ? 250 THR A CA  1 
ATOM 1969 C C   . THR A 1 266 ? 177.999 198.654 124.698 1.00 21.41 ? 250 THR A C   1 
ATOM 1970 O O   . THR A 1 266 ? 177.015 199.272 124.280 1.00 21.41 ? 250 THR A O   1 
ATOM 1971 C CB  . THR A 1 266 ? 179.011 200.865 125.298 1.00 21.41 ? 250 THR A CB  1 
ATOM 1972 O OG1 . THR A 1 266 ? 178.318 201.438 124.182 1.00 21.41 ? 250 THR A OG1 1 
ATOM 1973 C CG2 . THR A 1 266 ? 180.312 201.622 125.524 1.00 21.41 ? 250 THR A CG2 1 
ATOM 1974 N N   . HIS A 1 267 ? 177.991 197.340 124.896 1.00 20.32 ? 251 HIS A N   1 
ATOM 1975 C CA  . HIS A 1 267 ? 176.818 196.519 124.627 1.00 20.32 ? 251 HIS A CA  1 
ATOM 1976 C C   . HIS A 1 267 ? 176.858 195.310 125.552 1.00 20.32 ? 251 HIS A C   1 
ATOM 1977 O O   . HIS A 1 267 ? 177.790 195.135 126.341 1.00 20.32 ? 251 HIS A O   1 
ATOM 1978 C CB  . HIS A 1 267 ? 176.759 196.097 123.156 1.00 20.32 ? 251 HIS A CB  1 
ATOM 1979 C CG  . HIS A 1 267 ? 176.194 197.144 122.248 1.00 20.32 ? 251 HIS A CG  1 
ATOM 1980 N ND1 . HIS A 1 267 ? 175.371 198.153 122.698 1.00 20.32 ? 251 HIS A ND1 1 
ATOM 1981 C CD2 . HIS A 1 267 ? 176.332 197.337 120.915 1.00 20.32 ? 251 HIS A CD2 1 
ATOM 1982 C CE1 . HIS A 1 267 ? 175.027 198.924 121.682 1.00 20.32 ? 251 HIS A CE1 1 
ATOM 1983 N NE2 . HIS A 1 267 ? 175.597 198.451 120.588 1.00 20.32 ? 251 HIS A NE2 1 
ATOM 1984 N N   . SER A 1 268 ? 175.826 194.471 125.449 1.00 13.15 ? 252 SER A N   1 
ATOM 1985 C CA  . SER A 1 268 ? 175.736 193.252 126.253 1.00 13.15 ? 252 SER A CA  1 
ATOM 1986 C C   . SER A 1 268 ? 175.028 192.198 125.398 1.00 13.15 ? 252 SER A C   1 
ATOM 1987 O O   . SER A 1 268 ? 173.798 192.127 125.370 1.00 13.15 ? 252 SER A O   1 
ATOM 1988 C CB  . SER A 1 268 ? 175.003 193.500 127.563 1.00 13.15 ? 252 SER A CB  1 
ATOM 1989 O OG  . SER A 1 268 ? 173.677 193.940 127.328 1.00 13.15 ? 252 SER A OG  1 
ATOM 1990 N N   . LEU A 1 269 ? 175.823 191.382 124.710 1.00 9.77  ? 253 LEU A N   1 
ATOM 1991 C CA  . LEU A 1 269 ? 175.294 190.344 123.827 1.00 9.77  ? 253 LEU A CA  1 
ATOM 1992 C C   . LEU A 1 269 ? 174.786 189.196 124.687 1.00 9.77  ? 253 LEU A C   1 
ATOM 1993 O O   . LEU A 1 269 ? 175.480 188.205 124.918 1.00 9.77  ? 253 LEU A O   1 
ATOM 1994 C CB  . LEU A 1 269 ? 176.360 189.872 122.845 1.00 9.77  ? 253 LEU A CB  1 
ATOM 1995 C CG  . LEU A 1 269 ? 176.617 190.728 121.602 1.00 9.77  ? 253 LEU A CG  1 
ATOM 1996 C CD1 . LEU A 1 269 ? 175.306 191.133 120.949 1.00 9.77  ? 253 LEU A CD1 1 
ATOM 1997 C CD2 . LEU A 1 269 ? 177.460 191.950 121.933 1.00 9.77  ? 253 LEU A CD2 1 
ATOM 1998 N N   . ALA A 1 270 ? 173.548 189.326 125.161 1.00 5.63  ? 254 ALA A N   1 
ATOM 1999 C CA  . ALA A 1 270 ? 172.944 188.290 125.989 1.00 5.63  ? 254 ALA A CA  1 
ATOM 2000 C C   . ALA A 1 270 ? 172.546 187.093 125.137 1.00 5.63  ? 254 ALA A C   1 
ATOM 2001 O O   . ALA A 1 270 ? 171.355 186.851 124.916 1.00 5.63  ? 254 ALA A O   1 
ATOM 2002 C CB  . ALA A 1 270 ? 171.730 188.840 126.738 1.00 5.63  ? 254 ALA A CB  1 
ATOM 2003 N N   . VAL A 1 271 ? 173.536 186.339 124.653 1.00 5.10  ? 255 VAL A N   1 
ATOM 2004 C CA  . VAL A 1 271 ? 173.237 185.206 123.788 1.00 5.10  ? 255 VAL A CA  1 
ATOM 2005 C C   . VAL A 1 271 ? 172.592 184.086 124.596 1.00 5.10  ? 255 VAL A C   1 
ATOM 2006 O O   . VAL A 1 271 ? 172.627 184.062 125.832 1.00 5.10  ? 255 VAL A O   1 
ATOM 2007 C CB  . VAL A 1 271 ? 174.502 184.714 123.065 1.00 5.10  ? 255 VAL A CB  1 
ATOM 2008 C CG1 . VAL A 1 271 ? 175.277 185.889 122.498 1.00 5.10  ? 255 VAL A CG1 1 
ATOM 2009 C CG2 . VAL A 1 271 ? 175.369 183.894 124.000 1.00 5.10  ? 255 VAL A CG2 1 
ATOM 2010 N N   . SER A 1 272 ? 171.988 183.141 123.878 1.00 5.48  ? 256 SER A N   1 
ATOM 2011 C CA  . SER A 1 272 ? 171.275 182.015 124.480 1.00 5.48  ? 256 SER A CA  1 
ATOM 2012 C C   . SER A 1 272 ? 171.793 180.733 123.838 1.00 5.48  ? 256 SER A C   1 
ATOM 2013 O O   . SER A 1 272 ? 171.308 180.320 122.782 1.00 5.48  ? 256 SER A O   1 
ATOM 2014 C CB  . SER A 1 272 ? 169.769 182.163 124.302 1.00 5.48  ? 256 SER A CB  1 
ATOM 2015 O OG  . SER A 1 272 ? 169.410 182.058 122.936 1.00 5.48  ? 256 SER A OG  1 
ATOM 2016 N N   . LEU A 1 273 ? 172.780 180.110 124.476 1.00 7.16  ? 257 LEU A N   1 
ATOM 2017 C CA  . LEU A 1 273 ? 173.310 178.851 123.975 1.00 7.16  ? 257 LEU A CA  1 
ATOM 2018 C C   . LEU A 1 273 ? 172.244 177.766 124.041 1.00 7.16  ? 257 LEU A C   1 
ATOM 2019 O O   . LEU A 1 273 ? 171.419 177.736 124.958 1.00 7.16  ? 257 LEU A O   1 
ATOM 2020 C CB  . LEU A 1 273 ? 174.539 178.434 124.781 1.00 7.16  ? 257 LEU A CB  1 
ATOM 2021 C CG  . LEU A 1 273 ? 175.700 179.427 124.782 1.00 7.16  ? 257 LEU A CG  1 
ATOM 2022 C CD1 . LEU A 1 273 ? 176.876 178.874 125.565 1.00 7.16  ? 257 LEU A CD1 1 
ATOM 2023 C CD2 . LEU A 1 273 ? 176.110 179.761 123.361 1.00 7.16  ? 257 LEU A CD2 1 
ATOM 2024 N N   . HIS A 1 274 ? 172.262 176.873 123.056 1.00 13.66 ? 258 HIS A N   1 
ATOM 2025 C CA  . HIS A 1 274 ? 171.271 175.805 122.952 1.00 13.66 ? 258 HIS A CA  1 
ATOM 2026 C C   . HIS A 1 274 ? 172.007 174.497 122.710 1.00 13.66 ? 258 HIS A C   1 
ATOM 2027 O O   . HIS A 1 274 ? 172.528 174.270 121.614 1.00 13.66 ? 258 HIS A O   1 
ATOM 2028 C CB  . HIS A 1 274 ? 170.273 176.088 121.830 1.00 13.66 ? 258 HIS A CB  1 
ATOM 2029 C CG  . HIS A 1 274 ? 169.171 175.081 121.733 1.00 13.66 ? 258 HIS A CG  1 
ATOM 2030 N ND1 . HIS A 1 274 ? 169.304 173.896 121.041 1.00 13.66 ? 258 HIS A ND1 1 
ATOM 2031 C CD2 . HIS A 1 274 ? 167.914 175.084 122.236 1.00 13.66 ? 258 HIS A CD2 1 
ATOM 2032 C CE1 . HIS A 1 274 ? 168.178 173.211 121.125 1.00 13.66 ? 258 HIS A CE1 1 
ATOM 2033 N NE2 . HIS A 1 274 ? 167.318 173.910 121.844 1.00 13.66 ? 258 HIS A NE2 1 
ATOM 2034 N N   . CYS A 1 275 ? 172.054 173.642 123.730 1.00 17.43 ? 259 CYS A N   1 
ATOM 2035 C CA  . CYS A 1 275 ? 172.731 172.360 123.596 1.00 17.43 ? 259 CYS A CA  1 
ATOM 2036 C C   . CYS A 1 275 ? 171.984 171.459 122.622 1.00 17.43 ? 259 CYS A C   1 
ATOM 2037 O O   . CYS A 1 275 ? 170.751 171.398 122.623 1.00 17.43 ? 259 CYS A O   1 
ATOM 2038 C CB  . CYS A 1 275 ? 172.851 171.679 124.959 1.00 17.43 ? 259 CYS A CB  1 
ATOM 2039 S SG  . CYS A 1 275 ? 173.770 172.634 126.185 1.00 17.43 ? 259 CYS A SG  1 
ATOM 2040 N N   . ALA A 1 276 ? 172.741 170.755 121.785 1.00 17.33 ? 260 ALA A N   1 
ATOM 2041 C CA  . ALA A 1 276 ? 172.165 169.849 120.807 1.00 17.33 ? 260 ALA A CA  1 
ATOM 2042 C C   . ALA A 1 276 ? 172.038 168.447 121.400 1.00 17.33 ? 260 ALA A C   1 
ATOM 2043 O O   . ALA A 1 276 ? 172.345 168.205 122.569 1.00 17.33 ? 260 ALA A O   1 
ATOM 2044 C CB  . ALA A 1 276 ? 173.006 169.836 119.531 1.00 17.33 ? 260 ALA A CB  1 
ATOM 2045 N N   . GLU A 1 277 ? 171.572 167.507 120.575 1.00 22.36 ? 261 GLU A N   1 
ATOM 2046 C CA  . GLU A 1 277 ? 171.404 166.135 121.039 1.00 22.36 ? 261 GLU A CA  1 
ATOM 2047 C C   . GLU A 1 277 ? 172.743 165.454 121.291 1.00 22.36 ? 261 GLU A C   1 
ATOM 2048 O O   . GLU A 1 277 ? 172.850 164.616 122.193 1.00 22.36 ? 261 GLU A O   1 
ATOM 2049 C CB  . GLU A 1 277 ? 170.583 165.338 120.025 1.00 22.36 ? 261 GLU A CB  1 
ATOM 2050 C CG  . GLU A 1 277 ? 169.279 166.007 119.623 1.00 22.36 ? 261 GLU A CG  1 
ATOM 2051 C CD  . GLU A 1 277 ? 168.541 165.246 118.540 1.00 22.36 ? 261 GLU A CD  1 
ATOM 2052 O OE1 . GLU A 1 277 ? 168.687 164.007 118.478 1.00 22.36 ? 261 GLU A OE1 1 
ATOM 2053 O OE2 . GLU A 1 277 ? 167.815 165.886 117.751 1.00 22.36 ? 261 GLU A OE2 1 
ATOM 2054 N N   . ASP A 1 278 ? 173.771 165.798 120.513 1.00 22.04 ? 262 ASP A N   1 
ATOM 2055 C CA  . ASP A 1 278 ? 175.089 165.187 120.631 1.00 22.04 ? 262 ASP A CA  1 
ATOM 2056 C C   . ASP A 1 278 ? 176.063 166.057 121.419 1.00 22.04 ? 262 ASP A C   1 
ATOM 2057 O O   . ASP A 1 278 ? 177.265 166.061 121.128 1.00 22.04 ? 262 ASP A O   1 
ATOM 2058 C CB  . ASP A 1 278 ? 175.654 164.879 119.245 1.00 22.04 ? 262 ASP A CB  1 
ATOM 2059 C CG  . ASP A 1 278 ? 174.739 163.987 118.431 1.00 22.04 ? 262 ASP A CG  1 
ATOM 2060 O OD1 . ASP A 1 278 ? 174.167 163.038 119.007 1.00 22.04 ? 262 ASP A OD1 1 
ATOM 2061 O OD2 . ASP A 1 278 ? 174.592 164.234 117.216 1.00 22.04 ? 262 ASP A OD2 1 
ATOM 2062 N N   . ASP A 1 279 ? 175.563 166.792 122.411 1.00 16.46 ? 263 ASP A N   1 
ATOM 2063 C CA  . ASP A 1 279 ? 176.379 167.637 123.283 1.00 16.46 ? 263 ASP A CA  1 
ATOM 2064 C C   . ASP A 1 279 ? 177.160 168.673 122.474 1.00 16.46 ? 263 ASP A C   1 
ATOM 2065 O O   . ASP A 1 279 ? 178.392 168.701 122.460 1.00 16.46 ? 263 ASP A O   1 
ATOM 2066 C CB  . ASP A 1 279 ? 177.315 166.788 124.147 1.00 16.46 ? 263 ASP A CB  1 
ATOM 2067 C CG  . ASP A 1 279 ? 176.577 165.712 124.918 1.00 16.46 ? 263 ASP A CG  1 
ATOM 2068 O OD1 . ASP A 1 279 ? 175.993 164.813 124.277 1.00 16.46 ? 263 ASP A OD1 1 
ATOM 2069 O OD2 . ASP A 1 279 ? 176.576 165.767 126.165 1.00 16.46 ? 263 ASP A OD2 1 
ATOM 2070 N N   . SER A 1 280 ? 176.409 169.534 121.790 1.00 16.30 ? 264 SER A N   1 
ATOM 2071 C CA  . SER A 1 280 ? 176.980 170.629 121.014 1.00 16.30 ? 264 SER A CA  1 
ATOM 2072 C C   . SER A 1 280 ? 176.172 171.885 121.294 1.00 16.30 ? 264 SER A C   1 
ATOM 2073 O O   . SER A 1 280 ? 174.940 171.856 121.227 1.00 16.30 ? 264 SER A O   1 
ATOM 2074 C CB  . SER A 1 280 ? 176.980 170.308 119.516 1.00 16.30 ? 264 SER A CB  1 
ATOM 2075 O OG  . SER A 1 280 ? 177.592 171.347 118.773 1.00 16.30 ? 264 SER A OG  1 
ATOM 2076 N N   . ILE A 1 281 ? 176.858 172.978 121.606 1.00 14.14 ? 265 ILE A N   1 
ATOM 2077 C CA  . ILE A 1 281 ? 176.190 174.227 121.950 1.00 14.14 ? 265 ILE A CA  1 
ATOM 2078 C C   . ILE A 1 281 ? 176.129 175.133 120.727 1.00 14.14 ? 265 ILE A C   1 
ATOM 2079 O O   . ILE A 1 281 ? 177.121 175.307 120.008 1.00 14.14 ? 265 ILE A O   1 
ATOM 2080 C CB  . ILE A 1 281 ? 176.902 174.912 123.131 1.00 14.14 ? 265 ILE A CB  1 
ATOM 2081 C CG1 . ILE A 1 281 ? 178.401 175.044 122.857 1.00 14.14 ? 265 ILE A CG1 1 
ATOM 2082 C CG2 . ILE A 1 281 ? 176.662 174.139 124.417 1.00 14.14 ? 265 ILE A CG2 1 
ATOM 2083 C CD1 . ILE A 1 281 ? 179.195 175.538 124.046 1.00 14.14 ? 265 ILE A CD1 1 
ATOM 2084 N N   . SER A 1 282 ? 174.952 175.705 120.480 1.00 13.45 ? 266 SER A N   1 
ATOM 2085 C CA  . SER A 1 282 ? 174.739 176.604 119.356 1.00 13.45 ? 266 SER A CA  1 
ATOM 2086 C C   . SER A 1 282 ? 173.983 177.837 119.831 1.00 13.45 ? 266 SER A C   1 
ATOM 2087 O O   . SER A 1 282 ? 173.124 177.755 120.712 1.00 13.45 ? 266 SER A O   1 
ATOM 2088 C CB  . SER A 1 282 ? 173.966 175.918 118.223 1.00 13.45 ? 266 SER A CB  1 
ATOM 2089 O OG  . SER A 1 282 ? 173.860 176.765 117.093 1.00 13.45 ? 266 SER A OG  1 
ATOM 2090 N N   . VAL A 1 283 ? 174.308 178.979 119.232 1.00 10.33 ? 267 VAL A N   1 
ATOM 2091 C CA  . VAL A 1 283 ? 173.706 180.252 119.616 1.00 10.33 ? 267 VAL A CA  1 
ATOM 2092 C C   . VAL A 1 283 ? 172.317 180.366 119.003 1.00 10.33 ? 267 VAL A C   1 
ATOM 2093 O O   . VAL A 1 283 ? 172.073 179.898 117.884 1.00 10.33 ? 267 VAL A O   1 
ATOM 2094 C CB  . VAL A 1 283 ? 174.605 181.424 119.188 1.00 10.33 ? 267 VAL A CB  1 
ATOM 2095 C CG1 . VAL A 1 283 ? 175.834 181.497 120.078 1.00 10.33 ? 267 VAL A CG1 1 
ATOM 2096 C CG2 . VAL A 1 283 ? 175.007 181.280 117.730 1.00 10.33 ? 267 VAL A CG2 1 
ATOM 2097 N N   . SER A 1 284 ? 171.395 180.979 119.741 1.00 8.82  ? 268 SER A N   1 
ATOM 2098 C CA  . SER A 1 284 ? 170.014 181.136 119.292 1.00 8.82  ? 268 SER A CA  1 
ATOM 2099 C C   . SER A 1 284 ? 169.475 182.512 119.677 1.00 8.82  ? 268 SER A C   1 
ATOM 2100 O O   . SER A 1 284 ? 168.344 182.655 120.143 1.00 8.82  ? 268 SER A O   1 
ATOM 2101 C CB  . SER A 1 284 ? 169.133 180.024 119.857 1.00 8.82  ? 268 SER A CB  1 
ATOM 2102 O OG  . SER A 1 284 ? 169.658 178.749 119.533 1.00 8.82  ? 268 SER A OG  1 
ATOM 2103 N N   . GLY A 1 285 ? 170.290 183.547 119.489 1.00 8.02  ? 269 GLY A N   1 
ATOM 2104 C CA  . GLY A 1 285 ? 169.838 184.907 119.721 1.00 8.02  ? 269 GLY A CA  1 
ATOM 2105 C C   . GLY A 1 285 ? 170.939 185.844 120.168 1.00 8.02  ? 269 GLY A C   1 
ATOM 2106 O O   . GLY A 1 285 ? 171.748 185.488 121.029 1.00 8.02  ? 269 GLY A O   1 
ATOM 2107 N N   . GLN A 1 286 ? 170.988 187.043 119.591 1.00 7.89  ? 270 GLN A N   1 
ATOM 2108 C CA  . GLN A 1 286 ? 172.018 188.032 119.906 1.00 7.89  ? 270 GLN A CA  1 
ATOM 2109 C C   . GLN A 1 286 ? 171.373 189.319 120.415 1.00 7.89  ? 270 GLN A C   1 
ATOM 2110 O O   . GLN A 1 286 ? 171.673 190.418 119.949 1.00 7.89  ? 270 GLN A O   1 
ATOM 2111 C CB  . GLN A 1 286 ? 172.917 188.348 118.706 1.00 7.89  ? 270 GLN A CB  1 
ATOM 2112 C CG  . GLN A 1 286 ? 174.172 187.477 118.492 1.00 7.89  ? 270 GLN A CG  1 
ATOM 2113 C CD  . GLN A 1 286 ? 173.913 186.064 117.991 1.00 7.89  ? 270 GLN A CD  1 
ATOM 2114 O OE1 . GLN A 1 286 ? 172.935 185.421 118.349 1.00 7.89  ? 270 GLN A OE1 1 
ATOM 2115 N NE2 . GLN A 1 286 ? 174.813 185.576 117.146 1.00 7.89  ? 270 GLN A NE2 1 
ATOM 2116 N N   . ASN A 1 287 ? 170.469 189.190 121.384 1.00 10.64 ? 271 ASN A N   1 
ATOM 2117 C CA  . ASN A 1 287 ? 169.836 190.362 121.975 1.00 10.64 ? 271 ASN A CA  1 
ATOM 2118 C C   . ASN A 1 287 ? 170.871 191.208 122.710 1.00 10.64 ? 271 ASN A C   1 
ATOM 2119 O O   . ASN A 1 287 ? 171.828 190.684 123.287 1.00 10.64 ? 271 ASN A O   1 
ATOM 2120 C CB  . ASN A 1 287 ? 168.724 189.936 122.932 1.00 10.64 ? 271 ASN A CB  1 
ATOM 2121 C CG  . ASN A 1 287 ? 167.799 191.078 123.300 1.00 10.64 ? 271 ASN A CG  1 
ATOM 2122 O OD1 . ASN A 1 287 ? 168.241 192.203 123.527 1.00 10.64 ? 271 ASN A OD1 1 
ATOM 2123 N ND2 . ASN A 1 287 ? 166.505 190.792 123.361 1.00 10.64 ? 271 ASN A ND2 1 
ATOM 2124 N N   . SER A 1 288 ? 170.676 192.527 122.691 1.00 12.98 ? 272 SER A N   1 
ATOM 2125 C CA  . SER A 1 288 ? 171.664 193.462 123.210 1.00 12.98 ? 272 SER A CA  1 
ATOM 2126 C C   . SER A 1 288 ? 171.001 194.538 124.059 1.00 12.98 ? 272 SER A C   1 
ATOM 2127 O O   . SER A 1 288 ? 169.813 194.833 123.905 1.00 12.98 ? 272 SER A O   1 
ATOM 2128 C CB  . SER A 1 288 ? 172.452 194.125 122.072 1.00 12.98 ? 272 SER A CB  1 
ATOM 2129 O OG  . SER A 1 288 ? 172.816 193.177 121.086 1.00 12.98 ? 272 SER A OG  1 
ATOM 2130 N N   . LEU A 1 289 ? 171.791 195.119 124.962 1.00 19.13 ? 273 LEU A N   1 
ATOM 2131 C CA  . LEU A 1 289 ? 171.380 196.263 125.763 1.00 19.13 ? 273 LEU A CA  1 
ATOM 2132 C C   . LEU A 1 289 ? 172.540 197.240 125.878 1.00 19.13 ? 273 LEU A C   1 
ATOM 2133 O O   . LEU A 1 289 ? 173.704 196.868 125.710 1.00 19.13 ? 273 LEU A O   1 
ATOM 2134 C CB  . LEU A 1 289 ? 170.909 195.853 127.163 1.00 19.13 ? 273 LEU A CB  1 
ATOM 2135 C CG  . LEU A 1 289 ? 169.397 195.874 127.394 1.00 19.13 ? 273 LEU A CG  1 
ATOM 2136 C CD1 . LEU A 1 289 ? 169.081 195.819 128.880 1.00 19.13 ? 273 LEU A CD1 1 
ATOM 2137 C CD2 . LEU A 1 289 ? 168.768 197.102 126.753 1.00 19.13 ? 273 LEU A CD2 1 
ATOM 2138 N N   . CYS A 1 290 ? 172.210 198.499 126.168 1.00 25.16 ? 274 CYS A N   1 
ATOM 2139 C CA  . CYS A 1 290 ? 173.215 199.551 126.264 1.00 25.16 ? 274 CYS A CA  1 
ATOM 2140 C C   . CYS A 1 290 ? 173.640 199.829 127.702 1.00 25.16 ? 274 CYS A C   1 
ATOM 2141 O O   . CYS A 1 290 ? 174.809 200.143 127.950 1.00 25.16 ? 274 CYS A O   1 
ATOM 2142 C CB  . CYS A 1 290 ? 172.691 200.838 125.622 1.00 25.16 ? 274 CYS A CB  1 
ATOM 2143 S SG  . CYS A 1 290 ? 173.868 202.211 125.630 1.00 25.16 ? 274 CYS A SG  1 
ATOM 2144 N N   . HIS A 1 291 ? 172.716 199.723 128.654 1.00 20.44 ? 275 HIS A N   1 
ATOM 2145 C CA  . HIS A 1 291 ? 173.032 200.024 130.043 1.00 20.44 ? 275 HIS A CA  1 
ATOM 2146 C C   . HIS A 1 291 ? 173.960 198.967 130.632 1.00 20.44 ? 275 HIS A C   1 
ATOM 2147 O O   . HIS A 1 291 ? 174.019 197.827 130.164 1.00 20.44 ? 275 HIS A O   1 
ATOM 2148 C CB  . HIS A 1 291 ? 171.753 200.116 130.876 1.00 20.44 ? 275 HIS A CB  1 
ATOM 2149 C CG  . HIS A 1 291 ? 170.815 201.195 130.432 1.00 20.44 ? 275 HIS A CG  1 
ATOM 2150 N ND1 . HIS A 1 291 ? 170.272 201.237 129.166 1.00 20.44 ? 275 HIS A ND1 1 
ATOM 2151 C CD2 . HIS A 1 291 ? 170.322 202.272 131.088 1.00 20.44 ? 275 HIS A CD2 1 
ATOM 2152 C CE1 . HIS A 1 291 ? 169.485 202.293 129.061 1.00 20.44 ? 275 HIS A CE1 1 
ATOM 2153 N NE2 . HIS A 1 291 ? 169.498 202.938 130.213 1.00 20.44 ? 275 HIS A NE2 1 
ATOM 2154 N N   . GLN A 1 292 ? 174.691 199.361 131.671 1.00 14.66 ? 276 GLN A N   1 
ATOM 2155 C CA  . GLN A 1 292 ? 175.602 198.440 132.332 1.00 14.66 ? 276 GLN A CA  1 
ATOM 2156 C C   . GLN A 1 292 ? 174.822 197.366 133.085 1.00 14.66 ? 276 GLN A C   1 
ATOM 2157 O O   . GLN A 1 292 ? 173.626 197.499 133.358 1.00 14.66 ? 276 GLN A O   1 
ATOM 2158 C CB  . GLN A 1 292 ? 176.528 199.192 133.289 1.00 14.66 ? 276 GLN A CB  1 
ATOM 2159 C CG  . GLN A 1 292 ? 175.925 199.475 134.656 1.00 14.66 ? 276 GLN A CG  1 
ATOM 2160 C CD  . GLN A 1 292 ? 176.970 199.854 135.687 1.00 14.66 ? 276 GLN A CD  1 
ATOM 2161 O OE1 . GLN A 1 292 ? 178.133 200.084 135.355 1.00 14.66 ? 276 GLN A OE1 1 
ATOM 2162 N NE2 . GLN A 1 292 ? 176.560 199.923 136.948 1.00 14.66 ? 276 GLN A NE2 1 
ATOM 2163 N N   . ILE A 1 293 ? 175.521 196.285 133.420 1.00 10.29 ? 277 ILE A N   1 
ATOM 2164 C CA  . ILE A 1 293 ? 174.927 195.119 134.062 1.00 10.29 ? 277 ILE A CA  1 
ATOM 2165 C C   . ILE A 1 293 ? 175.543 194.960 135.443 1.00 10.29 ? 277 ILE A C   1 
ATOM 2166 O O   . ILE A 1 293 ? 176.771 194.971 135.585 1.00 10.29 ? 277 ILE A O   1 
ATOM 2167 C CB  . ILE A 1 293 ? 175.132 193.846 133.222 1.00 10.29 ? 277 ILE A CB  1 
ATOM 2168 C CG1 . ILE A 1 293 ? 174.470 193.998 131.851 1.00 10.29 ? 277 ILE A CG1 1 
ATOM 2169 C CG2 . ILE A 1 293 ? 174.602 192.629 133.958 1.00 10.29 ? 277 ILE A CG2 1 
ATOM 2170 C CD1 . ILE A 1 293 ? 173.030 194.455 131.914 1.00 10.29 ? 277 ILE A CD1 1 
ATOM 2171 N N   . THR A 1 294 ? 174.692 194.814 136.457 1.00 7.49  ? 278 THR A N   1 
ATOM 2172 C CA  . THR A 1 294 ? 175.136 194.610 137.831 1.00 7.49  ? 278 THR A CA  1 
ATOM 2173 C C   . THR A 1 294 ? 174.994 193.161 138.281 1.00 7.49  ? 278 THR A C   1 
ATOM 2174 O O   . THR A 1 294 ? 175.933 192.591 138.844 1.00 7.49  ? 278 THR A O   1 
ATOM 2175 C CB  . THR A 1 294 ? 174.358 195.526 138.779 1.00 7.49  ? 278 THR A CB  1 
ATOM 2176 O OG1 . THR A 1 294 ? 174.285 196.842 138.218 1.00 7.49  ? 278 THR A OG1 1 
ATOM 2177 C CG2 . THR A 1 294 ? 175.050 195.594 140.123 1.00 7.49  ? 278 THR A CG2 1 
ATOM 2178 N N   . ALA A 1 295 ? 173.831 192.556 138.053 1.00 4.49  ? 279 ALA A N   1 
ATOM 2179 C CA  . ALA A 1 295 ? 173.621 191.151 138.363 1.00 4.49  ? 279 ALA A CA  1 
ATOM 2180 C C   . ALA A 1 295 ? 172.552 190.604 137.430 1.00 4.49  ? 279 ALA A C   1 
ATOM 2181 O O   . ALA A 1 295 ? 171.705 191.345 136.925 1.00 4.49  ? 279 ALA A O   1 
ATOM 2182 C CB  . ALA A 1 295 ? 173.220 190.945 139.827 1.00 4.49  ? 279 ALA A CB  1 
ATOM 2183 N N   . ALA A 1 296 ? 172.599 189.295 137.205 1.00 2.52  ? 280 ALA A N   1 
ATOM 2184 C CA  . ALA A 1 296 ? 171.675 188.646 136.289 1.00 2.52  ? 280 ALA A CA  1 
ATOM 2185 C C   . ALA A 1 296 ? 171.182 187.343 136.896 1.00 2.52  ? 280 ALA A C   1 
ATOM 2186 O O   . ALA A 1 296 ? 171.876 186.707 137.693 1.00 2.52  ? 280 ALA A O   1 
ATOM 2187 C CB  . ALA A 1 296 ? 172.325 188.375 134.927 1.00 2.52  ? 280 ALA A CB  1 
ATOM 2188 N N   . CYS A 1 297 ? 169.971 186.953 136.508 1.00 2.16  ? 281 CYS A N   1 
ATOM 2189 C CA  . CYS A 1 297 ? 169.377 185.705 136.958 1.00 2.16  ? 281 CYS A CA  1 
ATOM 2190 C C   . CYS A 1 297 ? 168.348 185.258 135.935 1.00 2.16  ? 281 CYS A C   1 
ATOM 2191 O O   . CYS A 1 297 ? 167.667 186.088 135.329 1.00 2.16  ? 281 CYS A O   1 
ATOM 2192 C CB  . CYS A 1 297 ? 168.719 185.856 138.332 1.00 2.16  ? 281 CYS A CB  1 
ATOM 2193 S SG  . CYS A 1 297 ? 167.446 184.623 138.672 1.00 2.16  ? 281 CYS A SG  1 
ATOM 2194 N N   . LYS A 1 298 ? 168.238 183.946 135.749 1.00 4.19  ? 282 LYS A N   1 
ATOM 2195 C CA  . LYS A 1 298 ? 167.266 183.363 134.834 1.00 4.19  ? 282 LYS A CA  1 
ATOM 2196 C C   . LYS A 1 298 ? 166.235 182.601 135.654 1.00 4.19  ? 282 LYS A C   1 
ATOM 2197 O O   . LYS A 1 298 ? 166.588 181.912 136.616 1.00 4.19  ? 282 LYS A O   1 
ATOM 2198 C CB  . LYS A 1 298 ? 167.947 182.459 133.799 1.00 4.19  ? 282 LYS A CB  1 
ATOM 2199 C CG  . LYS A 1 298 ? 168.276 181.055 134.269 1.00 4.19  ? 282 LYS A CG  1 
ATOM 2200 C CD  . LYS A 1 298 ? 168.543 180.130 133.095 1.00 4.19  ? 282 LYS A CD  1 
ATOM 2201 C CE  . LYS A 1 298 ? 167.340 180.043 132.176 1.00 4.19  ? 282 LYS A CE  1 
ATOM 2202 N NZ  . LYS A 1 298 ? 167.315 178.758 131.427 1.00 4.19  ? 282 LYS A NZ  1 
ATOM 2203 N N   . HIS A 1 299 ? 164.965 182.761 135.299 1.00 5.29  ? 283 HIS A N   1 
ATOM 2204 C CA  . HIS A 1 299 ? 163.854 182.157 136.028 1.00 5.29  ? 283 HIS A CA  1 
ATOM 2205 C C   . HIS A 1 299 ? 163.008 181.373 135.031 1.00 5.29  ? 283 HIS A C   1 
ATOM 2206 O O   . HIS A 1 299 ? 162.140 181.937 134.360 1.00 5.29  ? 283 HIS A O   1 
ATOM 2207 C CB  . HIS A 1 299 ? 163.035 183.226 136.744 1.00 5.29  ? 283 HIS A CB  1 
ATOM 2208 C CG  . HIS A 1 299 ? 161.853 182.687 137.485 1.00 5.29  ? 283 HIS A CG  1 
ATOM 2209 N ND1 . HIS A 1 299 ? 161.947 182.169 138.759 1.00 5.29  ? 283 HIS A ND1 1 
ATOM 2210 C CD2 . HIS A 1 299 ? 160.549 182.590 137.135 1.00 5.29  ? 283 HIS A CD2 1 
ATOM 2211 C CE1 . HIS A 1 299 ? 160.752 181.773 139.160 1.00 5.29  ? 283 HIS A CE1 1 
ATOM 2212 N NE2 . HIS A 1 299 ? 159.886 182.017 138.194 1.00 5.29  ? 283 HIS A NE2 1 
ATOM 2213 N N   . GLY A 1 300 ? 163.267 180.073 134.938 1.00 5.70  ? 284 GLY A N   1 
ATOM 2214 C CA  . GLY A 1 300 ? 162.553 179.219 134.012 1.00 5.70  ? 284 GLY A CA  1 
ATOM 2215 C C   . GLY A 1 300 ? 163.111 179.275 132.605 1.00 5.70  ? 284 GLY A C   1 
ATOM 2216 O O   . GLY A 1 300 ? 163.811 178.354 132.174 1.00 5.70  ? 284 GLY A O   1 
ATOM 2217 N N   . GLY A 1 301 ? 162.809 180.347 131.877 1.00 6.84  ? 285 GLY A N   1 
ATOM 2218 C CA  . GLY A 1 301 ? 163.339 180.509 130.538 1.00 6.84  ? 285 GLY A CA  1 
ATOM 2219 C C   . GLY A 1 301 ? 163.629 181.944 130.146 1.00 6.84  ? 285 GLY A C   1 
ATOM 2220 O O   . GLY A 1 301 ? 163.953 182.216 128.986 1.00 6.84  ? 285 GLY A O   1 
ATOM 2221 N N   . ASP A 1 302 ? 163.515 182.873 131.093 1.00 7.63  ? 286 ASP A N   1 
ATOM 2222 C CA  . ASP A 1 302 ? 163.660 184.293 130.809 1.00 7.63  ? 286 ASP A CA  1 
ATOM 2223 C C   . ASP A 1 302 ? 164.726 184.910 131.702 1.00 7.63  ? 286 ASP A C   1 
ATOM 2224 O O   . ASP A 1 302 ? 164.863 184.551 132.875 1.00 7.63  ? 286 ASP A O   1 
ATOM 2225 C CB  . ASP A 1 302 ? 162.337 185.052 131.009 1.00 7.63  ? 286 ASP A CB  1 
ATOM 2226 C CG  . ASP A 1 302 ? 161.129 184.272 130.525 1.00 7.63  ? 286 ASP A CG  1 
ATOM 2227 O OD1 . ASP A 1 302 ? 160.040 184.442 131.113 1.00 7.63  ? 286 ASP A OD1 1 
ATOM 2228 O OD2 . ASP A 1 302 ? 161.256 183.512 129.544 1.00 7.63  ? 286 ASP A OD2 1 
ATOM 2229 N N   . LEU A 1 303 ? 165.479 185.847 131.132 1.00 5.77  ? 287 LEU A N   1 
ATOM 2230 C CA  . LEU A 1 303 ? 166.421 186.636 131.912 1.00 5.77  ? 287 LEU A CA  1 
ATOM 2231 C C   . LEU A 1 303 ? 165.682 187.631 132.796 1.00 5.77  ? 287 LEU A C   1 
ATOM 2232 O O   . LEU A 1 303 ? 164.543 188.018 132.521 1.00 5.77  ? 287 LEU A O   1 
ATOM 2233 C CB  . LEU A 1 303 ? 167.382 187.395 130.998 1.00 5.77  ? 287 LEU A CB  1 
ATOM 2234 C CG  . LEU A 1 303 ? 168.570 186.663 130.382 1.00 5.77  ? 287 LEU A CG  1 
ATOM 2235 C CD1 . LEU A 1 303 ? 169.137 187.473 129.229 1.00 5.77  ? 287 LEU A CD1 1 
ATOM 2236 C CD2 . LEU A 1 303 ? 169.639 186.407 131.426 1.00 5.77  ? 287 LEU A CD2 1 
ATOM 2237 N N   . TYR A 1 304 ? 166.339 188.037 133.876 1.00 4.67  ? 288 TYR A N   1 
ATOM 2238 C CA  . TYR A 1 304 ? 165.842 189.103 134.739 1.00 4.67  ? 288 TYR A CA  1 
ATOM 2239 C C   . TYR A 1 304 ? 167.001 190.013 135.132 1.00 4.67  ? 288 TYR A C   1 
ATOM 2240 O O   . TYR A 1 304 ? 167.222 190.309 136.306 1.00 4.67  ? 288 TYR A O   1 
ATOM 2241 C CB  . TYR A 1 304 ? 165.127 188.530 135.959 1.00 4.67  ? 288 TYR A CB  1 
ATOM 2242 C CG  . TYR A 1 304 ? 163.692 188.150 135.679 1.00 4.67  ? 288 TYR A CG  1 
ATOM 2243 C CD1 . TYR A 1 304 ? 163.359 186.862 135.287 1.00 4.67  ? 288 TYR A CD1 1 
ATOM 2244 C CD2 . TYR A 1 304 ? 162.672 189.084 135.789 1.00 4.67  ? 288 TYR A CD2 1 
ATOM 2245 C CE1 . TYR A 1 304 ? 162.051 186.511 135.024 1.00 4.67  ? 288 TYR A CE1 1 
ATOM 2246 C CE2 . TYR A 1 304 ? 161.361 188.743 135.526 1.00 4.67  ? 288 TYR A CE2 1 
ATOM 2247 C CZ  . TYR A 1 304 ? 161.057 187.456 135.145 1.00 4.67  ? 288 TYR A CZ  1 
ATOM 2248 O OH  . TYR A 1 304 ? 159.751 187.111 134.883 1.00 4.67  ? 288 TYR A OH  1 
ATOM 2249 N N   . VAL A 1 305 ? 167.762 190.455 134.127 1.00 4.25  ? 289 VAL A N   1 
ATOM 2250 C CA  . VAL A 1 305 ? 168.993 191.192 134.378 1.00 4.25  ? 289 VAL A CA  1 
ATOM 2251 C C   . VAL A 1 305 ? 168.709 192.480 135.149 1.00 4.25  ? 289 VAL A C   1 
ATOM 2252 O O   . VAL A 1 305 ? 167.621 193.065 135.062 1.00 4.25  ? 289 VAL A O   1 
ATOM 2253 C CB  . VAL A 1 305 ? 169.719 191.488 133.054 1.00 4.25  ? 289 VAL A CB  1 
ATOM 2254 C CG1 . VAL A 1 305 ? 169.163 192.742 132.399 1.00 4.25  ? 289 VAL A CG1 1 
ATOM 2255 C CG2 . VAL A 1 305 ? 171.213 191.609 133.281 1.00 4.25  ? 289 VAL A CG2 1 
ATOM 2256 N N   . VAL A 1 306 ? 169.697 192.913 135.927 1.00 5.78  ? 290 VAL A N   1 
ATOM 2257 C CA  . VAL A 1 306 ? 169.593 194.094 136.777 1.00 5.78  ? 290 VAL A CA  1 
ATOM 2258 C C   . VAL A 1 306 ? 170.760 195.011 136.447 1.00 5.78  ? 290 VAL A C   1 
ATOM 2259 O O   . VAL A 1 306 ? 171.919 194.577 136.461 1.00 5.78  ? 290 VAL A O   1 
ATOM 2260 C CB  . VAL A 1 306 ? 169.600 193.725 138.267 1.00 5.78  ? 290 VAL A CB  1 
ATOM 2261 C CG1 . VAL A 1 306 ? 169.567 194.975 139.116 1.00 5.78  ? 290 VAL A CG1 1 
ATOM 2262 C CG2 . VAL A 1 306 ? 168.430 192.826 138.594 1.00 5.78  ? 290 VAL A CG2 1 
ATOM 2263 N N   . GLY A 1 307 ? 170.463 196.271 136.157 1.00 10.43 ? 291 GLY A N   1 
ATOM 2264 C CA  . GLY A 1 307 ? 171.520 197.202 135.822 1.00 10.43 ? 291 GLY A CA  1 
ATOM 2265 C C   . GLY A 1 307 ? 170.965 198.560 135.461 1.00 10.43 ? 291 GLY A C   1 
ATOM 2266 O O   . GLY A 1 307 ? 169.773 198.833 135.618 1.00 10.43 ? 291 GLY A O   1 
ATOM 2267 N N   . GLY A 1 308 ? 171.859 199.409 134.966 1.00 17.20 ? 292 GLY A N   1 
ATOM 2268 C CA  . GLY A 1 308 ? 171.525 200.770 134.592 1.00 17.20 ? 292 GLY A CA  1 
ATOM 2269 C C   . GLY A 1 308 ? 171.898 201.763 135.675 1.00 17.20 ? 292 GLY A C   1 
ATOM 2270 O O   . GLY A 1 308 ? 172.307 201.413 136.786 1.00 17.20 ? 292 GLY A O   1 
ATOM 2271 N N   . SER A 1 309 ? 171.753 203.038 135.326 1.00 17.70 ? 293 SER A N   1 
ATOM 2272 C CA  . SER A 1 309 ? 172.011 204.101 136.281 1.00 17.70 ? 293 SER A CA  1 
ATOM 2273 C C   . SER A 1 309 ? 170.912 204.131 137.340 1.00 17.70 ? 293 SER A C   1 
ATOM 2274 O O   . SER A 1 309 ? 169.857 203.505 137.201 1.00 17.70 ? 293 SER A O   1 
ATOM 2275 C CB  . SER A 1 309 ? 172.110 205.450 135.571 1.00 17.70 ? 293 SER A CB  1 
ATOM 2276 O OG  . SER A 1 309 ? 173.386 205.623 134.980 1.00 17.70 ? 293 SER A OG  1 
ATOM 2277 N N   . ILE A 1 310 ? 171.174 204.864 138.415 1.00 23.30 ? 294 ILE A N   1 
ATOM 2278 C CA  . ILE A 1 310 ? 170.208 204.941 139.518 1.00 23.30 ? 294 ILE A CA  1 
ATOM 2279 C C   . ILE A 1 310 ? 168.932 205.614 139.025 1.00 23.30 ? 294 ILE A C   1 
ATOM 2280 O O   . ILE A 1 310 ? 169.007 206.562 138.223 1.00 23.30 ? 294 ILE A O   1 
ATOM 2281 C CB  . ILE A 1 310 ? 170.812 205.698 140.703 1.00 23.30 ? 294 ILE A CB  1 
ATOM 2282 C CG1 . ILE A 1 310 ? 171.339 207.064 140.258 1.00 23.30 ? 294 ILE A CG1 1 
ATOM 2283 C CG2 . ILE A 1 310 ? 171.921 204.876 141.347 1.00 23.30 ? 294 ILE A CG2 1 
ATOM 2284 C CD1 . ILE A 1 310 ? 172.132 207.791 141.320 1.00 23.30 ? 294 ILE A CD1 1 
ATOM 2285 N N   . PRO A 1 311 ? 167.745 205.160 139.451 1.00 18.69 ? 295 PRO A N   1 
ATOM 2286 C CA  . PRO A 1 311 ? 167.482 204.038 140.367 1.00 18.69 ? 295 PRO A CA  1 
ATOM 2287 C C   . PRO A 1 311 ? 167.701 202.688 139.694 1.00 18.69 ? 295 PRO A C   1 
ATOM 2288 O O   . PRO A 1 311 ? 167.583 202.577 138.478 1.00 18.69 ? 295 PRO A O   1 
ATOM 2289 C CB  . PRO A 1 311 ? 166.014 204.255 140.753 1.00 18.69 ? 295 PRO A CB  1 
ATOM 2290 C CG  . PRO A 1 311 ? 165.416 204.877 139.527 1.00 18.69 ? 295 PRO A CG  1 
ATOM 2291 C CD  . PRO A 1 311 ? 166.493 205.791 138.994 1.00 18.69 ? 295 PRO A CD  1 
ATOM 2292 N N   . ARG A 1 312 ? 168.011 201.645 140.464 1.00 19.75 ? 296 ARG A N   1 
ATOM 2293 C CA  . ARG A 1 312 ? 168.337 200.340 139.900 1.00 19.75 ? 296 ARG A CA  1 
ATOM 2294 C C   . ARG A 1 312 ? 167.149 199.739 139.157 1.00 19.75 ? 296 ARG A C   1 
ATOM 2295 O O   . ARG A 1 312 ? 166.150 199.352 139.772 1.00 19.75 ? 296 ARG A O   1 
ATOM 2296 C CB  . ARG A 1 312 ? 168.815 199.395 141.003 1.00 19.75 ? 296 ARG A CB  1 
ATOM 2297 C CG  . ARG A 1 312 ? 169.712 198.278 140.511 1.00 19.75 ? 296 ARG A CG  1 
ATOM 2298 C CD  . ARG A 1 312 ? 170.941 198.821 139.803 1.00 19.75 ? 296 ARG A CD  1 
ATOM 2299 N NE  . ARG A 1 312 ? 171.767 199.639 140.682 1.00 19.75 ? 296 ARG A NE  1 
ATOM 2300 C CZ  . ARG A 1 312 ? 171.998 200.933 140.504 1.00 19.75 ? 296 ARG A CZ  1 
ATOM 2301 N NH1 . ARG A 1 312 ? 171.476 201.595 139.484 1.00 19.75 ? 296 ARG A NH1 1 
ATOM 2302 N NH2 . ARG A 1 312 ? 172.775 201.578 141.369 1.00 19.75 ? 296 ARG A NH2 1 
ATOM 2303 N N   . ARG A 1 313 ? 167.260 199.652 137.834 1.00 15.66 ? 297 ARG A N   1 
ATOM 2304 C CA  . ARG A 1 313 ? 166.179 199.204 136.974 1.00 15.66 ? 297 ARG A CA  1 
ATOM 2305 C C   . ARG A 1 313 ? 166.219 197.685 136.809 1.00 15.66 ? 297 ARG A C   1 
ATOM 2306 O O   . ARG A 1 313 ? 167.141 197.002 137.262 1.00 15.66 ? 297 ARG A O   1 
ATOM 2307 C CB  . ARG A 1 313 ? 166.278 199.891 135.612 1.00 15.66 ? 297 ARG A CB  1 
ATOM 2308 C CG  . ARG A 1 313 ? 164.950 200.270 134.967 1.00 15.66 ? 297 ARG A CG  1 
ATOM 2309 C CD  . ARG A 1 313 ? 164.398 201.560 135.553 1.00 15.66 ? 297 ARG A CD  1 
ATOM 2310 N NE  . ARG A 1 313 ? 163.191 202.004 134.866 1.00 15.66 ? 297 ARG A NE  1 
ATOM 2311 C CZ  . ARG A 1 313 ? 161.965 201.603 135.169 1.00 15.66 ? 297 ARG A CZ  1 
ATOM 2312 N NH1 . ARG A 1 313 ? 161.743 200.744 136.151 1.00 15.66 ? 297 ARG A NH1 1 
ATOM 2313 N NH2 . ARG A 1 313 ? 160.936 202.075 134.471 1.00 15.66 ? 297 ARG A NH2 1 
ATOM 2314 N N   . MET A 1 314 ? 165.200 197.149 136.142 1.00 9.10  ? 298 MET A N   1 
ATOM 2315 C CA  . MET A 1 314 ? 165.172 195.750 135.728 1.00 9.10  ? 298 MET A CA  1 
ATOM 2316 C C   . MET A 1 314 ? 164.635 195.649 134.312 1.00 9.10  ? 298 MET A C   1 
ATOM 2317 O O   . MET A 1 314 ? 163.641 196.299 133.975 1.00 9.10  ? 298 MET A O   1 
ATOM 2318 C CB  . MET A 1 314 ? 164.332 194.887 136.670 1.00 9.10  ? 298 MET A CB  1 
ATOM 2319 C CG  . MET A 1 314 ? 164.947 193.526 136.897 1.00 9.10  ? 298 MET A CG  1 
ATOM 2320 S SD  . MET A 1 314 ? 164.089 192.515 138.099 1.00 9.10  ? 298 MET A SD  1 
ATOM 2321 C CE  . MET A 1 314 ? 165.067 192.933 139.527 1.00 9.10  ? 298 MET A CE  1 
ATOM 2322 N N   . TRP A 1 315 ? 165.304 194.850 133.487 1.00 9.29  ? 299 TRP A N   1 
ATOM 2323 C CA  . TRP A 1 315 ? 164.850 194.531 132.142 1.00 9.29  ? 299 TRP A CA  1 
ATOM 2324 C C   . TRP A 1 315 ? 164.699 193.021 132.027 1.00 9.29  ? 299 TRP A C   1 
ATOM 2325 O O   . TRP A 1 315 ? 165.614 192.276 132.392 1.00 9.29  ? 299 TRP A O   1 
ATOM 2326 C CB  . TRP A 1 315 ? 165.840 195.047 131.095 1.00 9.29  ? 299 TRP A CB  1 
ATOM 2327 C CG  . TRP A 1 315 ? 166.522 196.327 131.474 1.00 9.29  ? 299 TRP A CG  1 
ATOM 2328 C CD1 . TRP A 1 315 ? 167.694 196.457 132.161 1.00 9.29  ? 299 TRP A CD1 1 
ATOM 2329 C CD2 . TRP A 1 315 ? 166.075 197.655 131.189 1.00 9.29  ? 299 TRP A CD2 1 
ATOM 2330 N NE1 . TRP A 1 315 ? 168.005 197.785 132.320 1.00 9.29  ? 299 TRP A NE1 1 
ATOM 2331 C CE2 . TRP A 1 315 ? 167.026 198.542 131.732 1.00 9.29  ? 299 TRP A CE2 1 
ATOM 2332 C CE3 . TRP A 1 315 ? 164.963 198.183 130.526 1.00 9.29  ? 299 TRP A CE3 1 
ATOM 2333 C CZ2 . TRP A 1 315 ? 166.898 199.925 131.634 1.00 9.29  ? 299 TRP A CZ2 1 
ATOM 2334 C CZ3 . TRP A 1 315 ? 164.838 199.556 130.429 1.00 9.29  ? 299 TRP A CZ3 1 
ATOM 2335 C CH2 . TRP A 1 315 ? 165.800 200.411 130.980 1.00 9.29  ? 299 TRP A CH2 1 
ATOM 2336 N N   . LYS A 1 316 ? 163.555 192.570 131.521 1.00 8.25  ? 300 LYS A N   1 
ATOM 2337 C CA  . LYS A 1 316 ? 163.289 191.150 131.332 1.00 8.25  ? 300 LYS A CA  1 
ATOM 2338 C C   . LYS A 1 316 ? 163.288 190.827 129.845 1.00 8.25  ? 300 LYS A C   1 
ATOM 2339 O O   . LYS A 1 316 ? 162.612 191.498 129.059 1.00 8.25  ? 300 LYS A O   1 
ATOM 2340 C CB  . LYS A 1 316 ? 161.953 190.744 131.960 1.00 8.25  ? 300 LYS A CB  1 
ATOM 2341 C CG  . LYS A 1 316 ? 161.512 189.336 131.587 1.00 8.25  ? 300 LYS A CG  1 
ATOM 2342 C CD  . LYS A 1 316 ? 160.051 189.087 131.925 1.00 8.25  ? 300 LYS A CD  1 
ATOM 2343 C CE  . LYS A 1 316 ? 159.602 187.730 131.405 1.00 8.25  ? 300 LYS A CE  1 
ATOM 2344 N NZ  . LYS A 1 316 ? 158.204 187.409 131.800 1.00 8.25  ? 300 LYS A NZ  1 
ATOM 2345 N N   . CYS A 1 317 ? 164.035 189.797 129.468 1.00 9.44  ? 301 CYS A N   1 
ATOM 2346 C CA  . CYS A 1 317 ? 164.184 189.374 128.083 1.00 9.44  ? 301 CYS A CA  1 
ATOM 2347 C C   . CYS A 1 317 ? 163.575 187.988 127.900 1.00 9.44  ? 301 CYS A C   1 
ATOM 2348 O O   . CYS A 1 317 ? 163.052 187.383 128.839 1.00 9.44  ? 301 CYS A O   1 
ATOM 2349 C CB  . CYS A 1 317 ? 165.658 189.383 127.669 1.00 9.44  ? 301 CYS A CB  1 
ATOM 2350 S SG  . CYS A 1 317 ? 165.970 188.786 125.993 1.00 9.44  ? 301 CYS A SG  1 
ATOM 2351 N N   . ASN A 1 318 ? 163.648 187.488 126.669 1.00 13.58 ? 302 ASN A N   1 
ATOM 2352 C CA  . ASN A 1 318 ? 163.141 186.163 126.344 1.00 13.58 ? 302 ASN A CA  1 
ATOM 2353 C C   . ASN A 1 318 ? 163.828 185.678 125.077 1.00 13.58 ? 302 ASN A C   1 
ATOM 2354 O O   . ASN A 1 318 ? 164.376 186.467 124.304 1.00 13.58 ? 302 ASN A O   1 
ATOM 2355 C CB  . ASN A 1 318 ? 161.616 186.171 126.167 1.00 13.58 ? 302 ASN A CB  1 
ATOM 2356 C CG  . ASN A 1 318 ? 161.009 184.781 126.233 1.00 13.58 ? 302 ASN A CG  1 
ATOM 2357 O OD1 . ASN A 1 318 ? 161.646 183.793 125.866 1.00 13.58 ? 302 ASN A OD1 1 
ATOM 2358 N ND2 . ASN A 1 318 ? 159.769 184.700 126.700 1.00 13.58 ? 302 ASN A ND2 1 
ATOM 2359 N N   . ASN A 1 319 ? 163.799 184.359 124.874 1.00 15.14 ? 303 ASN A N   1 
ATOM 2360 C CA  . ASN A 1 319 ? 164.418 183.785 123.684 1.00 15.14 ? 303 ASN A CA  1 
ATOM 2361 C C   . ASN A 1 319 ? 163.668 184.174 122.415 1.00 15.14 ? 303 ASN A C   1 
ATOM 2362 O O   . ASN A 1 319 ? 164.292 184.523 121.407 1.00 15.14 ? 303 ASN A O   1 
ATOM 2363 C CB  . ASN A 1 319 ? 164.493 182.264 123.809 1.00 15.14 ? 303 ASN A CB  1 
ATOM 2364 C CG  . ASN A 1 319 ? 164.733 181.582 122.476 1.00 15.14 ? 303 ASN A CG  1 
ATOM 2365 O OD1 . ASN A 1 319 ? 163.812 181.033 121.871 1.00 15.14 ? 303 ASN A OD1 1 
ATOM 2366 N ND2 . ASN A 1 319 ? 165.975 181.620 122.007 1.00 15.14 ? 303 ASN A ND2 1 
ATOM 2367 N N   . ALA A 1 320 ? 162.336 184.124 122.447 1.00 15.14 ? 304 ALA A N   1 
ATOM 2368 C CA  . ALA A 1 320 ? 161.527 184.415 121.271 1.00 15.14 ? 304 ALA A CA  1 
ATOM 2369 C C   . ALA A 1 320 ? 161.121 185.878 121.158 1.00 15.14 ? 304 ALA A C   1 
ATOM 2370 O O   . ALA A 1 320 ? 160.898 186.355 120.040 1.00 15.14 ? 304 ALA A O   1 
ATOM 2371 C CB  . ALA A 1 320 ? 160.264 183.545 121.266 1.00 15.14 ? 304 ALA A CB  1 
ATOM 2372 N N   . THR A 1 321 ? 161.012 186.595 122.279 1.00 15.60 ? 305 THR A N   1 
ATOM 2373 C CA  . THR A 1 321 ? 160.606 187.995 122.221 1.00 15.60 ? 305 THR A CA  1 
ATOM 2374 C C   . THR A 1 321 ? 161.656 188.849 121.520 1.00 15.60 ? 305 THR A C   1 
ATOM 2375 O O   . THR A 1 321 ? 161.319 189.674 120.661 1.00 15.60 ? 305 THR A O   1 
ATOM 2376 C CB  . THR A 1 321 ? 160.339 188.523 123.631 1.00 15.60 ? 305 THR A CB  1 
ATOM 2377 O OG1 . THR A 1 321 ? 159.230 187.820 124.203 1.00 15.60 ? 305 THR A OG1 1 
ATOM 2378 C CG2 . THR A 1 321 ? 160.019 190.009 123.593 1.00 15.60 ? 305 THR A CG2 1 
ATOM 2379 N N   . VAL A 1 322 ? 162.933 188.646 121.855 1.00 14.45 ? 306 VAL A N   1 
ATOM 2380 C CA  . VAL A 1 322 ? 164.050 189.417 121.313 1.00 14.45 ? 306 VAL A CA  1 
ATOM 2381 C C   . VAL A 1 322 ? 163.770 190.906 121.490 1.00 14.45 ? 306 VAL A C   1 
ATOM 2382 O O   . VAL A 1 322 ? 164.000 191.711 120.580 1.00 14.45 ? 306 VAL A O   1 
ATOM 2383 C CB  . VAL A 1 322 ? 164.318 189.061 119.836 1.00 14.45 ? 306 VAL A CB  1 
ATOM 2384 C CG1 . VAL A 1 322 ? 165.743 189.435 119.443 1.00 14.45 ? 306 VAL A CG1 1 
ATOM 2385 C CG2 . VAL A 1 322 ? 164.083 187.577 119.593 1.00 14.45 ? 306 VAL A CG2 1 
ATOM 2386 N N   . ASP A 1 323 ? 163.260 191.277 122.663 1.00 17.45 ? 307 ASP A N   1 
ATOM 2387 C CA  . ASP A 1 323 ? 162.955 192.668 122.973 1.00 17.45 ? 307 ASP A CA  1 
ATOM 2388 C C   . ASP A 1 323 ? 162.814 192.799 124.481 1.00 17.45 ? 307 ASP A C   1 
ATOM 2389 O O   . ASP A 1 323 ? 162.027 192.072 125.094 1.00 17.45 ? 307 ASP A O   1 
ATOM 2390 C CB  . ASP A 1 323 ? 161.673 193.125 122.267 1.00 17.45 ? 307 ASP A CB  1 
ATOM 2391 C CG  . ASP A 1 323 ? 161.377 194.595 122.487 1.00 17.45 ? 307 ASP A CG  1 
ATOM 2392 O OD1 . ASP A 1 323 ? 162.163 195.439 122.006 1.00 17.45 ? 307 ASP A OD1 1 
ATOM 2393 O OD2 . ASP A 1 323 ? 160.358 194.907 123.138 1.00 17.45 ? 307 ASP A OD2 1 
ATOM 2394 N N   . TRP A 1 324 ? 163.570 193.720 125.073 1.00 14.28 ? 308 TRP A N   1 
ATOM 2395 C CA  . TRP A 1 324 ? 163.601 193.850 126.522 1.00 14.28 ? 308 TRP A CA  1 
ATOM 2396 C C   . TRP A 1 324 ? 162.319 194.500 127.025 1.00 14.28 ? 308 TRP A C   1 
ATOM 2397 O O   . TRP A 1 324 ? 161.868 195.510 126.478 1.00 14.28 ? 308 TRP A O   1 
ATOM 2398 C CB  . TRP A 1 324 ? 164.813 194.670 126.963 1.00 14.28 ? 308 TRP A CB  1 
ATOM 2399 C CG  . TRP A 1 324 ? 166.122 194.057 126.585 1.00 14.28 ? 308 TRP A CG  1 
ATOM 2400 C CD1 . TRP A 1 324 ? 166.759 194.166 125.386 1.00 14.28 ? 308 TRP A CD1 1 
ATOM 2401 C CD2 . TRP A 1 324 ? 166.944 193.211 127.400 1.00 14.28 ? 308 TRP A CD2 1 
ATOM 2402 N NE1 . TRP A 1 324 ? 167.935 193.459 125.407 1.00 14.28 ? 308 TRP A NE1 1 
ATOM 2403 C CE2 . TRP A 1 324 ? 168.070 192.859 126.631 1.00 14.28 ? 308 TRP A CE2 1 
ATOM 2404 C CE3 . TRP A 1 324 ? 166.840 192.722 128.704 1.00 14.28 ? 308 TRP A CE3 1 
ATOM 2405 C CZ2 . TRP A 1 324 ? 169.085 192.045 127.126 1.00 14.28 ? 308 TRP A CZ2 1 
ATOM 2406 C CZ3 . TRP A 1 324 ? 167.848 191.914 129.191 1.00 14.28 ? 308 TRP A CZ3 1 
ATOM 2407 C CH2 . TRP A 1 324 ? 168.955 191.583 128.405 1.00 14.28 ? 308 TRP A CH2 1 
ATOM 2408 N N   . GLU A 1 325 ? 161.735 193.917 128.067 1.00 18.25 ? 309 GLU A N   1 
ATOM 2409 C CA  . GLU A 1 325 ? 160.553 194.473 128.706 1.00 18.25 ? 309 GLU A CA  1 
ATOM 2410 C C   . GLU A 1 325 ? 160.973 195.279 129.935 1.00 18.25 ? 309 GLU A C   1 
ATOM 2411 O O   . GLU A 1 325 ? 162.159 195.520 130.173 1.00 18.25 ? 309 GLU A O   1 
ATOM 2412 C CB  . GLU A 1 325 ? 159.569 193.359 129.054 1.00 18.25 ? 309 GLU A CB  1 
ATOM 2413 C CG  . GLU A 1 325 ? 159.456 192.283 127.987 1.00 18.25 ? 309 GLU A CG  1 
ATOM 2414 C CD  . GLU A 1 325 ? 158.366 191.274 128.288 1.00 18.25 ? 309 GLU A CD  1 
ATOM 2415 O OE1 . GLU A 1 325 ? 158.289 190.250 127.577 1.00 18.25 ? 309 GLU A OE1 1 
ATOM 2416 O OE2 . GLU A 1 325 ? 157.585 191.505 129.235 1.00 18.25 ? 309 GLU A OE2 1 
ATOM 2417 N N   . TRP A 1 326 ? 159.996 195.710 130.731 1.00 18.39 ? 310 TRP A N   1 
ATOM 2418 C CA  . TRP A 1 326 ? 160.259 196.492 131.930 1.00 18.39 ? 310 TRP A CA  1 
ATOM 2419 C C   . TRP A 1 326 ? 159.464 195.909 133.089 1.00 18.39 ? 310 TRP A C   1 
ATOM 2420 O O   . TRP A 1 326 ? 158.320 195.476 132.923 1.00 18.39 ? 310 TRP A O   1 
ATOM 2421 C CB  . TRP A 1 326 ? 159.921 197.977 131.705 1.00 18.39 ? 310 TRP A CB  1 
ATOM 2422 C CG  . TRP A 1 326 ? 158.510 198.363 132.045 1.00 18.39 ? 310 TRP A CG  1 
ATOM 2423 C CD1 . TRP A 1 326 ? 157.441 198.383 131.196 1.00 18.39 ? 310 TRP A CD1 1 
ATOM 2424 C CD2 . TRP A 1 326 ? 158.025 198.831 133.309 1.00 18.39 ? 310 TRP A CD2 1 
ATOM 2425 N NE1 . TRP A 1 326 ? 156.316 198.807 131.861 1.00 18.39 ? 310 TRP A NE1 1 
ATOM 2426 C CE2 . TRP A 1 326 ? 156.649 199.091 133.159 1.00 18.39 ? 310 TRP A CE2 1 
ATOM 2427 C CE3 . TRP A 1 326 ? 158.618 199.045 134.556 1.00 18.39 ? 310 TRP A CE3 1 
ATOM 2428 C CZ2 . TRP A 1 326 ? 155.857 199.554 134.209 1.00 18.39 ? 310 TRP A CZ2 1 
ATOM 2429 C CZ3 . TRP A 1 326 ? 157.831 199.502 135.597 1.00 18.39 ? 310 TRP A CZ3 1 
ATOM 2430 C CH2 . TRP A 1 326 ? 156.466 199.752 135.417 1.00 18.39 ? 310 TRP A CH2 1 
ATOM 2431 N N   . CYS A 1 327 ? 160.085 195.895 134.267 1.00 14.97 ? 311 CYS A N   1 
ATOM 2432 C CA  . CYS A 1 327 ? 159.493 195.286 135.451 1.00 14.97 ? 311 CYS A CA  1 
ATOM 2433 C C   . CYS A 1 327 ? 159.615 196.267 136.612 1.00 14.97 ? 311 CYS A C   1 
ATOM 2434 O O   . CYS A 1 327 ? 160.168 197.362 136.471 1.00 14.97 ? 311 CYS A O   1 
ATOM 2435 C CB  . CYS A 1 327 ? 160.159 193.937 135.759 1.00 14.97 ? 311 CYS A CB  1 
ATOM 2436 S SG  . CYS A 1 327 ? 160.031 192.716 134.431 1.00 14.97 ? 311 CYS A SG  1 
ATOM 2437 N N   . ALA A 1 328 ? 159.110 195.859 137.772 1.00 12.18 ? 312 ALA A N   1 
ATOM 2438 C CA  . ALA A 1 328 ? 159.035 196.755 138.918 1.00 12.18 ? 312 ALA A CA  1 
ATOM 2439 C C   . ALA A 1 328 ? 160.432 197.185 139.356 1.00 12.18 ? 312 ALA A C   1 
ATOM 2440 O O   . ALA A 1 328 ? 161.335 196.343 139.447 1.00 12.18 ? 312 ALA A O   1 
ATOM 2441 C CB  . ALA A 1 328 ? 158.307 196.075 140.076 1.00 12.18 ? 312 ALA A CB  1 
ATOM 2442 N N   . PRO A 1 329 ? 160.650 198.470 139.632 1.00 11.68 ? 313 PRO A N   1 
ATOM 2443 C CA  . PRO A 1 329 ? 161.992 198.931 140.005 1.00 11.68 ? 313 PRO A CA  1 
ATOM 2444 C C   . PRO A 1 329 ? 162.462 198.308 141.311 1.00 11.68 ? 313 PRO A C   1 
ATOM 2445 O O   . PRO A 1 329 ? 161.661 197.950 142.176 1.00 11.68 ? 313 PRO A O   1 
ATOM 2446 C CB  . PRO A 1 329 ? 161.820 200.449 140.137 1.00 11.68 ? 313 PRO A CB  1 
ATOM 2447 C CG  . PRO A 1 329 ? 160.622 200.767 139.304 1.00 11.68 ? 313 PRO A CG  1 
ATOM 2448 C CD  . PRO A 1 329 ? 159.709 199.590 139.468 1.00 11.68 ? 313 PRO A CD  1 
ATOM 2449 N N   . LEU A 1 330 ? 163.777 198.179 141.438 1.00 11.98 ? 314 LEU A N   1 
ATOM 2450 C CA  . LEU A 1 330 ? 164.378 197.569 142.618 1.00 11.98 ? 314 LEU A CA  1 
ATOM 2451 C C   . LEU A 1 330 ? 164.408 198.556 143.778 1.00 11.98 ? 314 LEU A C   1 
ATOM 2452 O O   . LEU A 1 330 ? 165.030 199.617 143.659 1.00 11.98 ? 314 LEU A O   1 
ATOM 2453 C CB  . LEU A 1 330 ? 165.793 197.103 142.303 1.00 11.98 ? 314 LEU A CB  1 
ATOM 2454 C CG  . LEU A 1 330 ? 166.527 196.292 143.371 1.00 11.98 ? 314 LEU A CG  1 
ATOM 2455 C CD1 . LEU A 1 330 ? 165.986 194.883 143.470 1.00 11.98 ? 314 LEU A CD1 1 
ATOM 2456 C CD2 . LEU A 1 330 ? 168.013 196.271 143.078 1.00 11.98 ? 314 LEU A CD2 1 
ATOM 2457 N N   . PRO A 1 331 ? 163.760 198.258 144.901 1.00 11.52 ? 315 PRO A N   1 
ATOM 2458 C CA  . PRO A 1 331 ? 163.991 199.045 146.115 1.00 11.52 ? 315 PRO A CA  1 
ATOM 2459 C C   . PRO A 1 331 ? 165.351 198.721 146.714 1.00 11.52 ? 315 PRO A C   1 
ATOM 2460 O O   . PRO A 1 331 ? 165.920 197.651 146.487 1.00 11.52 ? 315 PRO A O   1 
ATOM 2461 C CB  . PRO A 1 331 ? 162.855 198.610 147.051 1.00 11.52 ? 315 PRO A CB  1 
ATOM 2462 C CG  . PRO A 1 331 ? 161.869 197.889 146.170 1.00 11.52 ? 315 PRO A CG  1 
ATOM 2463 C CD  . PRO A 1 331 ? 162.692 197.265 145.093 1.00 11.52 ? 315 PRO A CD  1 
ATOM 2464 N N   . ARG A 1 332 ? 165.869 199.672 147.493 1.00 16.32 ? 316 ARG A N   1 
ATOM 2465 C CA  . ARG A 1 332 ? 167.163 199.530 148.162 1.00 16.32 ? 316 ARG A CA  1 
ATOM 2466 C C   . ARG A 1 332 ? 168.273 199.255 147.145 1.00 16.32 ? 316 ARG A C   1 
ATOM 2467 O O   . ARG A 1 332 ? 168.882 198.183 147.120 1.00 16.32 ? 316 ARG A O   1 
ATOM 2468 C CB  . ARG A 1 332 ? 167.110 198.433 149.232 1.00 16.32 ? 316 ARG A CB  1 
ATOM 2469 C CG  . ARG A 1 332 ? 165.927 198.537 150.178 1.00 16.32 ? 316 ARG A CG  1 
ATOM 2470 C CD  . ARG A 1 332 ? 166.344 199.112 151.520 1.00 16.32 ? 316 ARG A CD  1 
ATOM 2471 N NE  . ARG A 1 332 ? 167.284 198.238 152.212 1.00 16.32 ? 316 ARG A NE  1 
ATOM 2472 C CZ  . ARG A 1 332 ? 167.653 198.385 153.477 1.00 16.32 ? 316 ARG A CZ  1 
ATOM 2473 N NH1 . ARG A 1 332 ? 167.176 199.365 154.226 1.00 16.32 ? 316 ARG A NH1 1 
ATOM 2474 N NH2 . ARG A 1 332 ? 168.521 197.526 154.003 1.00 16.32 ? 316 ARG A NH2 1 
ATOM 2475 N N   . ASP A 1 333 ? 168.514 200.247 146.289 1.00 16.57 ? 317 ASP A N   1 
ATOM 2476 C CA  . ASP A 1 333 ? 169.478 200.093 145.206 1.00 16.57 ? 317 ASP A CA  1 
ATOM 2477 C C   . ASP A 1 333 ? 170.866 199.776 145.751 1.00 16.57 ? 317 ASP A C   1 
ATOM 2478 O O   . ASP A 1 333 ? 171.355 200.437 146.672 1.00 16.57 ? 317 ASP A O   1 
ATOM 2479 C CB  . ASP A 1 333 ? 169.520 201.363 144.356 1.00 16.57 ? 317 ASP A CB  1 
ATOM 2480 C CG  . ASP A 1 333 ? 169.807 202.605 145.176 1.00 16.57 ? 317 ASP A CG  1 
ATOM 2481 O OD1 . ASP A 1 333 ? 169.495 202.606 146.385 1.00 16.57 ? 317 ASP A OD1 1 
ATOM 2482 O OD2 . ASP A 1 333 ? 170.345 203.581 144.612 1.00 16.57 ? 317 ASP A OD2 1 
ATOM 2483 N N   . ARG A 1 334 ? 171.496 198.755 145.175 1.00 8.68  ? 318 ARG A N   1 
ATOM 2484 C CA  . ARG A 1 334 ? 172.828 198.334 145.584 1.00 8.68  ? 318 ARG A CA  1 
ATOM 2485 C C   . ARG A 1 334 ? 173.434 197.499 144.467 1.00 8.68  ? 318 ARG A C   1 
ATOM 2486 O O   . ARG A 1 334 ? 172.738 197.063 143.548 1.00 8.68  ? 318 ARG A O   1 
ATOM 2487 C CB  . ARG A 1 334 ? 172.792 197.546 146.897 1.00 8.68  ? 318 ARG A CB  1 
ATOM 2488 C CG  . ARG A 1 334 ? 171.885 196.330 146.867 1.00 8.68  ? 318 ARG A CG  1 
ATOM 2489 C CD  . ARG A 1 334 ? 171.900 195.601 148.199 1.00 8.68  ? 318 ARG A CD  1 
ATOM 2490 N NE  . ARG A 1 334 ? 171.174 194.340 148.136 1.00 8.68  ? 318 ARG A NE  1 
ATOM 2491 C CZ  . ARG A 1 334 ? 169.864 194.221 148.301 1.00 8.68  ? 318 ARG A CZ  1 
ATOM 2492 N NH1 . ARG A 1 334 ? 169.100 195.273 148.544 1.00 8.68  ? 318 ARG A NH1 1 
ATOM 2493 N NH2 . ARG A 1 334 ? 169.306 193.017 148.217 1.00 8.68  ? 318 ARG A NH2 1 
ATOM 2494 N N   . LEU A 1 335 ? 174.742 197.286 144.557 1.00 6.76  ? 319 LEU A N   1 
ATOM 2495 C CA  . LEU A 1 335 ? 175.479 196.529 143.558 1.00 6.76  ? 319 LEU A CA  1 
ATOM 2496 C C   . LEU A 1 335 ? 176.041 195.248 144.163 1.00 6.76  ? 319 LEU A C   1 
ATOM 2497 O O   . LEU A 1 335 ? 176.092 195.081 145.385 1.00 6.76  ? 319 LEU A O   1 
ATOM 2498 C CB  . LEU A 1 335 ? 176.614 197.363 142.948 1.00 6.76  ? 319 LEU A CB  1 
ATOM 2499 C CG  . LEU A 1 335 ? 177.717 197.937 143.842 1.00 6.76  ? 319 LEU A CG  1 
ATOM 2500 C CD1 . LEU A 1 335 ? 178.957 198.221 143.010 1.00 6.76  ? 319 LEU A CD1 1 
ATOM 2501 C CD2 . LEU A 1 335 ? 177.263 199.206 144.545 1.00 6.76  ? 319 LEU A CD2 1 
ATOM 2502 N N   . GLN A 1 336 ? 176.464 194.342 143.278 1.00 4.36  ? 320 GLN A N   1 
ATOM 2503 C CA  . GLN A 1 336 ? 177.011 193.034 143.644 1.00 4.36  ? 320 GLN A CA  1 
ATOM 2504 C C   . GLN A 1 336 ? 175.991 192.221 144.449 1.00 4.36  ? 320 GLN A C   1 
ATOM 2505 O O   . GLN A 1 336 ? 176.194 191.869 145.612 1.00 4.36  ? 320 GLN A O   1 
ATOM 2506 C CB  . GLN A 1 336 ? 178.331 193.189 144.408 1.00 4.36  ? 320 GLN A CB  1 
ATOM 2507 C CG  . GLN A 1 336 ? 179.514 193.546 143.524 1.00 4.36  ? 320 GLN A CG  1 
ATOM 2508 C CD  . GLN A 1 336 ? 180.819 192.971 144.035 1.00 4.36  ? 320 GLN A CD  1 
ATOM 2509 O OE1 . GLN A 1 336 ? 180.854 192.299 145.066 1.00 4.36  ? 320 GLN A OE1 1 
ATOM 2510 N NE2 . GLN A 1 336 ? 181.904 193.234 143.315 1.00 4.36  ? 320 GLN A NE2 1 
ATOM 2511 N N   . HIS A 1 337 ? 174.880 191.926 143.780 1.00 2.74  ? 321 HIS A N   1 
ATOM 2512 C CA  . HIS A 1 337 ? 173.801 191.146 144.371 1.00 2.74  ? 321 HIS A CA  1 
ATOM 2513 C C   . HIS A 1 337 ? 174.187 189.669 144.398 1.00 2.74  ? 321 HIS A C   1 
ATOM 2514 O O   . HIS A 1 337 ? 175.312 189.282 144.069 1.00 2.74  ? 321 HIS A O   1 
ATOM 2515 C CB  . HIS A 1 337 ? 172.504 191.352 143.595 1.00 2.74  ? 321 HIS A CB  1 
ATOM 2516 C CG  . HIS A 1 337 ? 172.068 192.779 143.505 1.00 2.74  ? 321 HIS A CG  1 
ATOM 2517 N ND1 . HIS A 1 337 ? 171.052 193.190 142.671 1.00 2.74  ? 321 HIS A ND1 1 
ATOM 2518 C CD2 . HIS A 1 337 ? 172.502 193.888 144.147 1.00 2.74  ? 321 HIS A CD2 1 
ATOM 2519 C CE1 . HIS A 1 337 ? 170.884 194.494 142.797 1.00 2.74  ? 321 HIS A CE1 1 
ATOM 2520 N NE2 . HIS A 1 337 ? 171.750 194.941 143.688 1.00 2.74  ? 321 HIS A NE2 1 
ATOM 2521 N N   . THR A 1 338 ? 173.241 188.825 144.799 1.00 0.80  ? 322 THR A N   1 
ATOM 2522 C CA  . THR A 1 338 ? 173.395 187.375 144.770 1.00 0.80  ? 322 THR A CA  1 
ATOM 2523 C C   . THR A 1 338 ? 172.093 186.739 144.289 1.00 0.80  ? 322 THR A C   1 
ATOM 2524 O O   . THR A 1 338 ? 171.556 185.821 144.908 1.00 0.80  ? 322 THR A O   1 
ATOM 2525 C CB  . THR A 1 338 ? 173.799 186.836 146.139 1.00 0.80  ? 322 THR A CB  1 
ATOM 2526 O OG1 . THR A 1 338 ? 174.692 187.761 146.769 1.00 0.80  ? 322 THR A OG1 1 
ATOM 2527 C CG2 . THR A 1 338 ? 174.506 185.501 145.995 1.00 0.80  ? 322 THR A CG2 1 
ATOM 2528 N N   . LEU A 1 339 ? 171.559 187.254 143.180 1.00 0.52  ? 323 LEU A N   1 
ATOM 2529 C CA  . LEU A 1 339 ? 170.241 186.851 142.700 1.00 0.52  ? 323 LEU A CA  1 
ATOM 2530 C C   . LEU A 1 339 ? 170.159 185.347 142.482 1.00 0.52  ? 323 LEU A C   1 
ATOM 2531 O O   . LEU A 1 339 ? 171.036 184.746 141.858 1.00 0.52  ? 323 LEU A O   1 
ATOM 2532 C CB  . LEU A 1 339 ? 169.911 187.573 141.393 1.00 0.52  ? 323 LEU A CB  1 
ATOM 2533 C CG  . LEU A 1 339 ? 169.772 189.094 141.400 1.00 0.52  ? 323 LEU A CG  1 
ATOM 2534 C CD1 . LEU A 1 339 ? 169.049 189.553 140.148 1.00 0.52  ? 323 LEU A CD1 1 
ATOM 2535 C CD2 . LEU A 1 339 ? 169.040 189.560 142.637 1.00 0.52  ? 323 LEU A CD2 1 
ATOM 2536 N N   . VAL A 1 340 ? 169.089 184.746 142.997 1.00 0.42  ? 324 VAL A N   1 
ATOM 2537 C CA  . VAL A 1 340 ? 168.783 183.340 142.778 1.00 0.42  ? 324 VAL A CA  1 
ATOM 2538 C C   . VAL A 1 340 ? 167.344 183.240 142.288 1.00 0.42  ? 324 VAL A C   1 
ATOM 2539 O O   . VAL A 1 340 ? 166.552 184.175 142.416 1.00 0.42  ? 324 VAL A O   1 
ATOM 2540 C CB  . VAL A 1 340 ? 168.987 182.482 144.041 1.00 0.42  ? 324 VAL A CB  1 
ATOM 2541 C CG1 . VAL A 1 340 ? 170.293 182.827 144.727 1.00 0.42  ? 324 VAL A CG1 1 
ATOM 2542 C CG2 . VAL A 1 340 ? 167.822 182.663 144.993 1.00 0.42  ? 324 VAL A CG2 1 
ATOM 2543 N N   . SER A 1 341 ? 166.964 182.052 141.755 1.00 1.39  ? 325 SER A N   1 
ATOM 2544 C CA  . SER A 1 341 ? 165.604 181.818 141.173 1.00 1.39  ? 325 SER A CA  1 
ATOM 2545 C C   . SER A 1 341 ? 165.066 180.395 141.452 1.00 1.39  ? 325 SER A C   1 
ATOM 2546 O O   . SER A 1 341 ? 165.832 179.456 141.164 1.00 1.39  ? 325 SER A O   1 
ATOM 2547 C CB  . SER A 1 341 ? 165.710 182.018 139.701 1.00 1.39  ? 325 SER A CB  1 
ATOM 2548 O OG  . SER A 1 341 ? 166.774 181.242 139.165 1.00 1.39  ? 325 SER A OG  1 
ATOM 2549 N N   . VAL A 1 342 ? 163.800 180.206 141.904 1.00 4.94  ? 326 VAL A N   1 
ATOM 2550 C CA  . VAL A 1 342 ? 163.268 178.854 142.277 1.00 4.94  ? 326 VAL A CA  1 
ATOM 2551 C C   . VAL A 1 342 ? 161.989 178.508 141.527 1.00 4.94  ? 326 VAL A C   1 
ATOM 2552 O O   . VAL A 1 342 ? 161.202 179.423 141.314 1.00 4.94  ? 326 VAL A O   1 
ATOM 2553 C CB  . VAL A 1 342 ? 162.925 178.776 143.766 1.00 4.94  ? 326 VAL A CB  1 
ATOM 2554 C CG1 . VAL A 1 342 ? 162.953 177.360 144.317 1.00 4.94  ? 326 VAL A CG1 1 
ATOM 2555 C CG2 . VAL A 1 342 ? 163.738 179.740 144.614 1.00 4.94  ? 326 VAL A CG2 1 
ATOM 2556 N N   . PRO A 1 343 ? 161.763 177.250 141.065 1.00 8.12  ? 327 PRO A N   1 
ATOM 2557 C CA  . PRO A 1 343 ? 160.472 176.811 140.476 1.00 8.12  ? 327 PRO A CA  1 
ATOM 2558 C C   . PRO A 1 343 ? 159.545 176.330 141.616 1.00 8.12  ? 327 PRO A C   1 
ATOM 2559 O O   . PRO A 1 343 ? 158.340 176.344 141.425 1.00 8.12  ? 327 PRO A O   1 
ATOM 2560 C CB  . PRO A 1 343 ? 160.851 175.709 139.461 1.00 8.12  ? 327 PRO A CB  1 
ATOM 2561 C CG  . PRO A 1 343 ? 162.102 175.096 140.060 1.00 8.12  ? 327 PRO A CG  1 
ATOM 2562 C CD  . PRO A 1 343 ? 162.760 176.181 140.900 1.00 8.12  ? 327 PRO A CD  1 
ATOM 2563 N N   . GLY A 1 344 ? 160.104 175.935 142.769 1.00 11.50 ? 328 GLY A N   1 
ATOM 2564 C CA  . GLY A 1 344 ? 159.282 175.571 143.932 1.00 11.50 ? 328 GLY A CA  1 
ATOM 2565 C C   . GLY A 1 344 ? 158.791 176.858 144.566 1.00 11.50 ? 328 GLY A C   1 
ATOM 2566 O O   . GLY A 1 344 ? 158.085 176.747 145.582 1.00 11.50 ? 328 GLY A O   1 
ATOM 2567 N N   . LYS A 1 345 ? 159.119 178.036 143.987 1.00 8.21  ? 329 LYS A N   1 
ATOM 2568 C CA  . LYS A 1 345 ? 158.697 179.377 144.508 1.00 8.21  ? 329 LYS A CA  1 
ATOM 2569 C C   . LYS A 1 345 ? 158.829 180.454 143.414 1.00 8.21  ? 329 LYS A C   1 
ATOM 2570 O O   . LYS A 1 345 ? 159.961 180.882 143.216 1.00 8.21  ? 329 LYS A O   1 
ATOM 2571 C CB  . LYS A 1 345 ? 159.559 179.740 145.727 1.00 8.21  ? 329 LYS A CB  1 
ATOM 2572 C CG  . LYS A 1 345 ? 159.008 179.368 147.096 1.00 8.21  ? 329 LYS A CG  1 
ATOM 2573 C CD  . LYS A 1 345 ? 159.167 180.468 148.123 1.00 8.21  ? 329 LYS A CD  1 
ATOM 2574 C CE  . LYS A 1 345 ? 158.082 181.523 148.048 1.00 8.21  ? 329 LYS A CE  1 
ATOM 2575 N NZ  . LYS A 1 345 ? 157.199 181.506 149.239 1.00 8.21  ? 329 LYS A NZ  1 
ATOM 2576 N N   . ASP A 1 346 ? 157.751 180.891 142.749 1.00 8.22  ? 330 ASP A N   1 
ATOM 2577 C CA  . ASP A 1 346 ? 157.726 181.901 141.691 1.00 8.22  ? 330 ASP A CA  1 
ATOM 2578 C C   . ASP A 1 346 ? 158.314 183.222 142.183 1.00 8.22  ? 330 ASP A C   1 
ATOM 2579 O O   . ASP A 1 346 ? 157.728 184.294 142.022 1.00 8.22  ? 330 ASP A O   1 
ATOM 2580 C CB  . ASP A 1 346 ? 156.308 182.095 141.152 1.00 8.22  ? 330 ASP A CB  1 
ATOM 2581 C CG  . ASP A 1 346 ? 156.024 181.231 139.941 1.00 8.22  ? 330 ASP A CG  1 
ATOM 2582 O OD1 . ASP A 1 346 ? 156.765 180.249 139.722 1.00 8.22  ? 330 ASP A OD1 1 
ATOM 2583 O OD2 . ASP A 1 346 ? 155.063 181.537 139.204 1.00 8.22  ? 330 ASP A OD2 1 
ATOM 2584 N N   . ALA A 1 347 ? 159.493 183.134 142.793 1.00 3.90  ? 331 ALA A N   1 
ATOM 2585 C CA  . ALA A 1 347 ? 160.139 184.278 143.413 1.00 3.90  ? 331 ALA A CA  1 
ATOM 2586 C C   . ALA A 1 347 ? 161.575 184.402 142.925 1.00 3.90  ? 331 ALA A C   1 
ATOM 2587 O O   . ALA A 1 347 ? 162.195 183.427 142.493 1.00 3.90  ? 331 ALA A O   1 
ATOM 2588 C CB  . ALA A 1 347 ? 160.118 184.170 144.943 1.00 3.90  ? 331 ALA A CB  1 
ATOM 2589 N N   . ILE A 1 348 ? 162.095 185.625 143.001 1.00 2.63  ? 332 ILE A N   1 
ATOM 2590 C CA  . ILE A 1 348 ? 163.479 185.936 142.653 1.00 2.63  ? 332 ILE A CA  1 
ATOM 2591 C C   . ILE A 1 348 ? 164.052 186.727 143.823 1.00 2.63  ? 332 ILE A C   1 
ATOM 2592 O O   . ILE A 1 348 ? 163.703 187.895 144.020 1.00 2.63  ? 332 ILE A O   1 
ATOM 2593 C CB  . ILE A 1 348 ? 163.594 186.725 141.345 1.00 2.63  ? 332 ILE A CB  1 
ATOM 2594 C CG1 . ILE A 1 348 ? 163.038 185.910 140.178 1.00 2.63  ? 332 ILE A CG1 1 
ATOM 2595 C CG2 . ILE A 1 348 ? 165.039 187.102 141.074 1.00 2.63  ? 332 ILE A CG2 1 
ATOM 2596 C CD1 . ILE A 1 348 ? 163.124 186.621 138.852 1.00 2.63  ? 332 ILE A CD1 1 
ATOM 2597 N N   . TYR A 1 349 ? 164.933 186.100 144.597 1.00 1.43  ? 333 TYR A N   1 
ATOM 2598 C CA  . TYR A 1 349 ? 165.478 186.735 145.786 1.00 1.43  ? 333 TYR A CA  1 
ATOM 2599 C C   . TYR A 1 349 ? 166.688 187.598 145.436 1.00 1.43  ? 333 TYR A C   1 
ATOM 2600 O O   . TYR A 1 349 ? 167.277 187.484 144.359 1.00 1.43  ? 333 TYR A O   1 
ATOM 2601 C CB  . TYR A 1 349 ? 165.858 185.684 146.827 1.00 1.43  ? 333 TYR A CB  1 
ATOM 2602 C CG  . TYR A 1 349 ? 164.669 185.057 147.518 1.00 1.43  ? 333 TYR A CG  1 
ATOM 2603 C CD1 . TYR A 1 349 ? 163.778 184.255 146.819 1.00 1.43  ? 333 TYR A CD1 1 
ATOM 2604 C CD2 . TYR A 1 349 ? 164.437 185.268 148.868 1.00 1.43  ? 333 TYR A CD2 1 
ATOM 2605 C CE1 . TYR A 1 349 ? 162.692 183.683 147.444 1.00 1.43  ? 333 TYR A CE1 1 
ATOM 2606 C CE2 . TYR A 1 349 ? 163.352 184.699 149.502 1.00 1.43  ? 333 TYR A CE2 1 
ATOM 2607 C CZ  . TYR A 1 349 ? 162.483 183.907 148.785 1.00 1.43  ? 333 TYR A CZ  1 
ATOM 2608 O OH  . TYR A 1 349 ? 161.400 183.337 149.413 1.00 1.43  ? 333 TYR A OH  1 
ATOM 2609 N N   . SER A 1 350 ? 167.049 188.477 146.367 1.00 1.26  ? 334 SER A N   1 
ATOM 2610 C CA  . SER A 1 350 ? 168.135 189.435 146.170 1.00 1.26  ? 334 SER A CA  1 
ATOM 2611 C C   . SER A 1 350 ? 169.008 189.512 147.419 1.00 1.26  ? 334 SER A C   1 
ATOM 2612 O O   . SER A 1 350 ? 169.312 190.591 147.928 1.00 1.26  ? 334 SER A O   1 
ATOM 2613 C CB  . SER A 1 350 ? 167.584 190.810 145.803 1.00 1.26  ? 334 SER A CB  1 
ATOM 2614 O OG  . SER A 1 350 ? 168.605 191.790 145.836 1.00 1.26  ? 334 SER A OG  1 
ATOM 2615 N N   . LEU A 1 351 ? 169.419 188.353 147.926 1.00 1.35  ? 335 LEU A N   1 
ATOM 2616 C CA  . LEU A 1 351 ? 170.173 188.292 149.170 1.00 1.35  ? 335 LEU A CA  1 
ATOM 2617 C C   . LEU A 1 351 ? 171.516 189.007 149.042 1.00 1.35  ? 335 LEU A C   1 
ATOM 2618 O O   . LEU A 1 351 ? 172.128 189.059 147.973 1.00 1.35  ? 335 LEU A O   1 
ATOM 2619 C CB  . LEU A 1 351 ? 170.415 186.841 149.586 1.00 1.35  ? 335 LEU A CB  1 
ATOM 2620 C CG  . LEU A 1 351 ? 169.238 185.869 149.578 1.00 1.35  ? 335 LEU A CG  1 
ATOM 2621 C CD1 . LEU A 1 351 ? 169.168 185.128 148.257 1.00 1.35  ? 335 LEU A CD1 1 
ATOM 2622 C CD2 . LEU A 1 351 ? 169.368 184.893 150.732 1.00 1.35  ? 335 LEU A CD2 1 
ATOM 2623 N N   . GLY A 1 352 ? 171.967 189.567 150.161 1.00 3.46  ? 336 GLY A N   1 
ATOM 2624 C CA  . GLY A 1 352 ? 173.285 190.160 150.238 1.00 3.46  ? 336 GLY A CA  1 
ATOM 2625 C C   . GLY A 1 352 ? 173.419 191.436 149.422 1.00 3.46  ? 336 GLY A C   1 
ATOM 2626 O O   . GLY A 1 352 ? 172.446 192.078 149.027 1.00 3.46  ? 336 GLY A O   1 
ATOM 2627 N N   . GLY A 1 353 ? 174.670 191.795 149.177 1.00 7.35  ? 337 GLY A N   1 
ATOM 2628 C CA  . GLY A 1 353 ? 175.006 192.957 148.385 1.00 7.35  ? 337 GLY A CA  1 
ATOM 2629 C C   . GLY A 1 353 ? 175.513 194.106 149.244 1.00 7.35  ? 337 GLY A C   1 
ATOM 2630 O O   . GLY A 1 353 ? 175.221 194.212 150.438 1.00 7.35  ? 337 GLY A O   1 
ATOM 2631 N N   . LYS A 1 354 ? 176.287 194.981 148.608 1.00 9.66  ? 338 LYS A N   1 
ATOM 2632 C CA  . LYS A 1 354 ? 176.839 196.162 149.253 1.00 9.66  ? 338 LYS A CA  1 
ATOM 2633 C C   . LYS A 1 354 ? 176.280 197.411 148.588 1.00 9.66  ? 338 LYS A C   1 
ATOM 2634 O O   . LYS A 1 354 ? 176.071 197.439 147.371 1.00 9.66  ? 338 LYS A O   1 
ATOM 2635 C CB  . LYS A 1 354 ? 178.372 196.170 149.190 1.00 9.66  ? 338 LYS A CB  1 
ATOM 2636 C CG  . LYS A 1 354 ? 178.945 196.199 147.784 1.00 9.66  ? 338 LYS A CG  1 
ATOM 2637 C CD  . LYS A 1 354 ? 180.423 196.557 147.799 1.00 9.66  ? 338 LYS A CD  1 
ATOM 2638 C CE  . LYS A 1 354 ? 181.257 195.431 148.386 1.00 9.66  ? 338 LYS A CE  1 
ATOM 2639 N NZ  . LYS A 1 354 ? 182.709 195.757 148.392 1.00 9.66  ? 338 LYS A NZ  1 
ATOM 2640 N N   . THR A 1 355 ? 176.032 198.440 149.395 1.00 15.23 ? 339 THR A N   1 
ATOM 2641 C CA  . THR A 1 355 ? 175.465 199.682 148.896 1.00 15.23 ? 339 THR A CA  1 
ATOM 2642 C C   . THR A 1 355 ? 176.516 200.473 148.119 1.00 15.23 ? 339 THR A C   1 
ATOM 2643 O O   . THR A 1 355 ? 177.676 200.069 147.992 1.00 15.23 ? 339 THR A O   1 
ATOM 2644 C CB  . THR A 1 355 ? 174.901 200.511 150.047 1.00 15.23 ? 339 THR A CB  1 
ATOM 2645 O OG1 . THR A 1 355 ? 175.930 200.743 151.018 1.00 15.23 ? 339 THR A OG1 1 
ATOM 2646 C CG2 . THR A 1 355 ? 173.741 199.783 150.709 1.00 15.23 ? 339 THR A CG2 1 
ATOM 2647 N N   . LEU A 1 356 ? 176.100 201.626 147.590 1.00 16.37 ? 340 LEU A N   1 
ATOM 2648 C CA  . LEU A 1 356 ? 177.012 202.457 146.812 1.00 16.37 ? 340 LEU A CA  1 
ATOM 2649 C C   . LEU A 1 356 ? 178.111 203.057 147.681 1.00 16.37 ? 340 LEU A C   1 
ATOM 2650 O O   . LEU A 1 356 ? 179.191 203.381 147.174 1.00 16.37 ? 340 LEU A O   1 
ATOM 2651 C CB  . LEU A 1 356 ? 176.234 203.563 146.098 1.00 16.37 ? 340 LEU A CB  1 
ATOM 2652 C CG  . LEU A 1 356 ? 175.104 203.107 145.172 1.00 16.37 ? 340 LEU A CG  1 
ATOM 2653 C CD1 . LEU A 1 356 ? 173.755 203.211 145.868 1.00 16.37 ? 340 LEU A CD1 1 
ATOM 2654 C CD2 . LEU A 1 356 ? 175.108 203.911 143.882 1.00 16.37 ? 340 LEU A CD2 1 
ATOM 2655 N N   . GLN A 1 357 ? 177.860 203.211 148.981 1.00 18.87 ? 341 GLN A N   1 
ATOM 2656 C CA  . GLN A 1 357 ? 178.832 203.773 149.908 1.00 18.87 ? 341 GLN A CA  1 
ATOM 2657 C C   . GLN A 1 357 ? 179.751 202.716 150.512 1.00 18.87 ? 341 GLN A C   1 
ATOM 2658 O O   . GLN A 1 357 ? 180.326 202.948 151.582 1.00 18.87 ? 341 GLN A O   1 
ATOM 2659 C CB  . GLN A 1 357 ? 178.114 204.547 151.015 1.00 18.87 ? 341 GLN A CB  1 
ATOM 2660 C CG  . GLN A 1 357 ? 176.864 203.863 151.539 1.00 18.87 ? 341 GLN A CG  1 
ATOM 2661 C CD  . GLN A 1 357 ? 176.191 204.650 152.645 1.00 18.87 ? 341 GLN A CD  1 
ATOM 2662 O OE1 . GLN A 1 357 ? 176.825 205.461 153.320 1.00 18.87 ? 341 GLN A OE1 1 
ATOM 2663 N NE2 . GLN A 1 357 ? 174.898 204.415 152.836 1.00 18.87 ? 341 GLN A NE2 1 
ATOM 2664 N N   . ASP A 1 358 ? 179.898 201.566 149.849 1.00 17.88 ? 342 ASP A N   1 
ATOM 2665 C CA  . ASP A 1 358 ? 180.797 200.495 150.284 1.00 17.88 ? 342 ASP A CA  1 
ATOM 2666 C C   . ASP A 1 358 ? 180.465 200.021 151.699 1.00 17.88 ? 342 ASP A C   1 
ATOM 2667 O O   . ASP A 1 358 ? 181.343 199.856 152.549 1.00 17.88 ? 342 ASP A O   1 
ATOM 2668 C CB  . ASP A 1 358 ? 182.260 200.933 150.181 1.00 17.88 ? 342 ASP A CB  1 
ATOM 2669 C CG  . ASP A 1 358 ? 182.707 201.131 148.746 1.00 17.88 ? 342 ASP A CG  1 
ATOM 2670 O OD1 . ASP A 1 358 ? 182.101 201.967 148.044 1.00 17.88 ? 342 ASP A OD1 1 
ATOM 2671 O OD2 . ASP A 1 358 ? 183.665 200.451 148.321 1.00 17.88 ? 342 ASP A OD2 1 
ATOM 2672 N N   . THR A 1 359 ? 179.176 199.802 151.949 1.00 18.00 ? 343 THR A N   1 
ATOM 2673 C CA  . THR A 1 359 ? 178.698 199.254 153.212 1.00 18.00 ? 343 THR A CA  1 
ATOM 2674 C C   . THR A 1 359 ? 178.006 197.928 152.931 1.00 18.00 ? 343 THR A C   1 
ATOM 2675 O O   . THR A 1 359 ? 177.062 197.875 152.137 1.00 18.00 ? 343 THR A O   1 
ATOM 2676 C CB  . THR A 1 359 ? 177.740 200.221 153.912 1.00 18.00 ? 343 THR A CB  1 
ATOM 2677 O OG1 . THR A 1 359 ? 176.559 200.384 153.118 1.00 18.00 ? 343 THR A OG1 1 
ATOM 2678 C CG2 . THR A 1 359 ? 178.402 201.575 154.111 1.00 18.00 ? 343 THR A CG2 1 
ATOM 2679 N N   . LEU A 1 360 ? 178.474 196.867 153.582 1.00 12.10 ? 344 LEU A N   1 
ATOM 2680 C CA  . LEU A 1 360 ? 177.923 195.529 153.377 1.00 12.10 ? 344 LEU A CA  1 
ATOM 2681 C C   . LEU A 1 360 ? 176.588 195.425 154.100 1.00 12.10 ? 344 LEU A C   1 
ATOM 2682 O O   . LEU A 1 360 ? 176.537 195.273 155.322 1.00 12.10 ? 344 LEU A O   1 
ATOM 2683 C CB  . LEU A 1 360 ? 178.901 194.470 153.872 1.00 12.10 ? 344 LEU A CB  1 
ATOM 2684 C CG  . LEU A 1 360 ? 180.346 194.618 153.393 1.00 12.10 ? 344 LEU A CG  1 
ATOM 2685 C CD1 . LEU A 1 360 ? 181.234 193.560 154.026 1.00 12.10 ? 344 LEU A CD1 1 
ATOM 2686 C CD2 . LEU A 1 360 ? 180.416 194.542 151.878 1.00 12.10 ? 344 LEU A CD2 1 
ATOM 2687 N N   . SER A 1 361 ? 175.498 195.506 153.346 1.00 12.82 ? 345 SER A N   1 
ATOM 2688 C CA  . SER A 1 361 ? 174.155 195.417 153.896 1.00 12.82 ? 345 SER A CA  1 
ATOM 2689 C C   . SER A 1 361 ? 173.620 193.996 153.762 1.00 12.82 ? 345 SER A C   1 
ATOM 2690 O O   . SER A 1 361 ? 174.177 193.155 153.055 1.00 12.82 ? 345 SER A O   1 
ATOM 2691 C CB  . SER A 1 361 ? 173.220 196.408 153.197 1.00 12.82 ? 345 SER A CB  1 
ATOM 2692 O OG  . SER A 1 361 ? 172.656 195.837 152.030 1.00 12.82 ? 345 SER A OG  1 
ATOM 2693 N N   . ASN A 1 362 ? 172.516 193.736 154.461 1.00 11.00 ? 346 ASN A N   1 
ATOM 2694 C CA  . ASN A 1 362 ? 171.862 192.428 154.431 1.00 11.00 ? 346 ASN A CA  1 
ATOM 2695 C C   . ASN A 1 362 ? 170.354 192.659 154.457 1.00 11.00 ? 346 ASN A C   1 
ATOM 2696 O O   . ASN A 1 362 ? 169.763 192.830 155.527 1.00 11.00 ? 346 ASN A O   1 
ATOM 2697 C CB  . ASN A 1 362 ? 172.315 191.553 155.594 1.00 11.00 ? 346 ASN A CB  1 
ATOM 2698 C CG  . ASN A 1 362 ? 172.338 192.300 156.913 1.00 11.00 ? 346 ASN A CG  1 
ATOM 2699 O OD1 . ASN A 1 362 ? 173.345 192.905 157.279 1.00 11.00 ? 346 ASN A OD1 1 
ATOM 2700 N ND2 . ASN A 1 362 ? 171.224 192.262 157.633 1.00 11.00 ? 346 ASN A ND2 1 
ATOM 2701 N N   . ALA A 1 363 ? 169.738 192.664 153.278 1.00 6.14  ? 347 ALA A N   1 
ATOM 2702 C CA  . ALA A 1 363 ? 168.298 192.866 153.152 1.00 6.14  ? 347 ALA A CA  1 
ATOM 2703 C C   . ALA A 1 363 ? 167.774 191.906 152.095 1.00 6.14  ? 347 ALA A C   1 
ATOM 2704 O O   . ALA A 1 363 ? 167.855 192.194 150.898 1.00 6.14  ? 347 ALA A O   1 
ATOM 2705 C CB  . ALA A 1 363 ? 167.970 194.314 152.786 1.00 6.14  ? 347 ALA A CB  1 
ATOM 2706 N N   . VAL A 1 364 ? 167.235 190.775 152.535 1.00 4.02  ? 348 VAL A N   1 
ATOM 2707 C CA  . VAL A 1 364 ? 166.696 189.780 151.617 1.00 4.02  ? 348 VAL A CA  1 
ATOM 2708 C C   . VAL A 1 364 ? 165.363 190.275 151.077 1.00 4.02  ? 348 VAL A C   1 
ATOM 2709 O O   . VAL A 1 364 ? 164.483 190.685 151.842 1.00 4.02  ? 348 VAL A O   1 
ATOM 2710 C CB  . VAL A 1 364 ? 166.540 188.422 152.315 1.00 4.02  ? 348 VAL A CB  1 
ATOM 2711 C CG1 . VAL A 1 364 ? 166.008 187.392 151.339 1.00 4.02  ? 348 VAL A CG1 1 
ATOM 2712 C CG2 . VAL A 1 364 ? 167.868 187.976 152.900 1.00 4.02  ? 348 VAL A CG2 1 
ATOM 2713 N N   . ILE A 1 365 ? 165.210 190.238 149.760 1.00 4.04  ? 349 ILE A N   1 
ATOM 2714 C CA  . ILE A 1 365 ? 164.009 190.723 149.109 1.00 4.04  ? 349 ILE A CA  1 
ATOM 2715 C C   . ILE A 1 365 ? 163.241 189.530 148.551 1.00 4.04  ? 349 ILE A C   1 
ATOM 2716 O O   . ILE A 1 365 ? 163.764 188.420 148.429 1.00 4.04  ? 349 ILE A O   1 
ATOM 2717 C CB  . ILE A 1 365 ? 164.343 191.754 148.011 1.00 4.04  ? 349 ILE A CB  1 
ATOM 2718 C CG1 . ILE A 1 365 ? 165.537 192.602 148.442 1.00 4.04  ? 349 ILE A CG1 1 
ATOM 2719 C CG2 . ILE A 1 365 ? 163.176 192.680 147.798 1.00 4.04  ? 349 ILE A CG2 1 
ATOM 2720 C CD1 . ILE A 1 365 ? 165.828 193.765 147.520 1.00 4.04  ? 349 ILE A CD1 1 
ATOM 2721 N N   . TYR A 1 366 ? 161.973 189.757 148.220 1.00 6.94  ? 350 TYR A N   1 
ATOM 2722 C CA  . TYR A 1 366 ? 161.019 188.695 147.909 1.00 6.94  ? 350 TYR A CA  1 
ATOM 2723 C C   . TYR A 1 366 ? 160.216 189.042 146.657 1.00 6.94  ? 350 TYR A C   1 
ATOM 2724 O O   . TYR A 1 366 ? 158.983 189.050 146.663 1.00 6.94  ? 350 TYR A O   1 
ATOM 2725 C CB  . TYR A 1 366 ? 160.106 188.450 149.110 1.00 6.94  ? 350 TYR A CB  1 
ATOM 2726 C CG  . TYR A 1 366 ? 159.115 187.313 148.960 1.00 6.94  ? 350 TYR A CG  1 
ATOM 2727 C CD1 . TYR A 1 366 ? 159.314 186.301 148.029 1.00 6.94  ? 350 TYR A CD1 1 
ATOM 2728 C CD2 . TYR A 1 366 ? 157.970 187.265 149.742 1.00 6.94  ? 350 TYR A CD2 1 
ATOM 2729 C CE1 . TYR A 1 366 ? 158.406 185.270 147.891 1.00 6.94  ? 350 TYR A CE1 1 
ATOM 2730 C CE2 . TYR A 1 366 ? 157.057 186.238 149.610 1.00 6.94  ? 350 TYR A CE2 1 
ATOM 2731 C CZ  . TYR A 1 366 ? 157.279 185.243 148.683 1.00 6.94  ? 350 TYR A CZ  1 
ATOM 2732 O OH  . TYR A 1 366 ? 156.371 184.218 148.549 1.00 6.94  ? 350 TYR A OH  1 
ATOM 2733 N N   . TYR A 1 367 ? 160.907 189.372 145.566 1.00 8.33  ? 351 TYR A N   1 
ATOM 2734 C CA  . TYR A 1 367 ? 160.218 189.670 144.315 1.00 8.33  ? 351 TYR A CA  1 
ATOM 2735 C C   . TYR A 1 367 ? 159.370 188.485 143.870 1.00 8.33  ? 351 TYR A C   1 
ATOM 2736 O O   . TYR A 1 367 ? 159.724 187.324 144.086 1.00 8.33  ? 351 TYR A O   1 
ATOM 2737 C CB  . TYR A 1 367 ? 161.219 190.025 143.214 1.00 8.33  ? 351 TYR A CB  1 
ATOM 2738 C CG  . TYR A 1 367 ? 160.593 190.216 141.845 1.00 8.33  ? 351 TYR A CG  1 
ATOM 2739 C CD1 . TYR A 1 367 ? 160.114 191.455 141.447 1.00 8.33  ? 351 TYR A CD1 1 
ATOM 2740 C CD2 . TYR A 1 367 ? 160.498 189.161 140.946 1.00 8.33  ? 351 TYR A CD2 1 
ATOM 2741 C CE1 . TYR A 1 367 ? 159.547 191.635 140.200 1.00 8.33  ? 351 TYR A CE1 1 
ATOM 2742 C CE2 . TYR A 1 367 ? 159.932 189.332 139.699 1.00 8.33  ? 351 TYR A CE2 1 
ATOM 2743 C CZ  . TYR A 1 367 ? 159.459 190.571 139.331 1.00 8.33  ? 351 TYR A CZ  1 
ATOM 2744 O OH  . TYR A 1 367 ? 158.896 190.749 138.089 1.00 8.33  ? 351 TYR A OH  1 
ATOM 2745 N N   . ARG A 1 368 ? 158.234 188.791 143.248 1.00 7.55  ? 352 ARG A N   1 
ATOM 2746 C CA  . ARG A 1 368 ? 157.345 187.786 142.686 1.00 7.55  ? 352 ARG A CA  1 
ATOM 2747 C C   . ARG A 1 368 ? 157.105 188.096 141.217 1.00 7.55  ? 352 ARG A C   1 
ATOM 2748 O O   . ARG A 1 368 ? 157.013 189.264 140.829 1.00 7.55  ? 352 ARG A O   1 
ATOM 2749 C CB  . ARG A 1 368 ? 156.012 187.734 143.440 1.00 7.55  ? 352 ARG A CB  1 
ATOM 2750 C CG  . ARG A 1 368 ? 156.149 187.370 144.908 1.00 7.55  ? 352 ARG A CG  1 
ATOM 2751 C CD  . ARG A 1 368 ? 154.801 187.371 145.608 1.00 7.55  ? 352 ARG A CD  1 
ATOM 2752 N NE  . ARG A 1 368 ? 153.958 186.265 145.171 1.00 7.55  ? 352 ARG A NE  1 
ATOM 2753 C CZ  . ARG A 1 368 ? 153.878 185.096 145.790 1.00 7.55  ? 352 ARG A CZ  1 
ATOM 2754 N NH1 . ARG A 1 368 ? 154.580 184.842 146.882 1.00 7.55  ? 352 ARG A NH1 1 
ATOM 2755 N NH2 . ARG A 1 368 ? 153.072 184.157 145.302 1.00 7.55  ? 352 ARG A NH2 1 
ATOM 2756 N N   . VAL A 1 369 ? 157.008 187.047 140.400 1.00 8.19  ? 353 VAL A N   1 
ATOM 2757 C CA  . VAL A 1 369 ? 156.817 187.243 138.967 1.00 8.19  ? 353 VAL A CA  1 
ATOM 2758 C C   . VAL A 1 369 ? 155.342 187.447 138.639 1.00 8.19  ? 353 VAL A C   1 
ATOM 2759 O O   . VAL A 1 369 ? 154.997 188.225 137.742 1.00 8.19  ? 353 VAL A O   1 
ATOM 2760 C CB  . VAL A 1 369 ? 157.422 186.061 138.186 1.00 8.19  ? 353 VAL A CB  1 
ATOM 2761 C CG1 . VAL A 1 369 ? 156.946 184.739 138.762 1.00 8.19  ? 353 VAL A CG1 1 
ATOM 2762 C CG2 . VAL A 1 369 ? 157.086 186.160 136.705 1.00 8.19  ? 353 VAL A CG2 1 
ATOM 2763 N N   . GLY A 1 370 ? 154.449 186.764 139.360 1.00 11.74 ? 354 GLY A N   1 
ATOM 2764 C CA  . GLY A 1 370 ? 153.027 186.923 139.099 1.00 11.74 ? 354 GLY A CA  1 
ATOM 2765 C C   . GLY A 1 370 ? 152.537 188.334 139.361 1.00 11.74 ? 354 GLY A C   1 
ATOM 2766 O O   . GLY A 1 370 ? 151.767 188.891 138.576 1.00 11.74 ? 354 GLY A O   1 
ATOM 2767 N N   . ASP A 1 371 ? 152.978 188.931 140.465 1.00 12.80 ? 355 ASP A N   1 
ATOM 2768 C CA  . ASP A 1 371 ? 152.652 190.310 140.804 1.00 12.80 ? 355 ASP A CA  1 
ATOM 2769 C C   . ASP A 1 371 ? 153.947 191.101 140.885 1.00 12.80 ? 355 ASP A C   1 
ATOM 2770 O O   . ASP A 1 371 ? 154.807 190.804 141.721 1.00 12.80 ? 355 ASP A O   1 
ATOM 2771 C CB  . ASP A 1 371 ? 151.886 190.385 142.126 1.00 12.80 ? 355 ASP A CB  1 
ATOM 2772 C CG  . ASP A 1 371 ? 150.738 189.399 142.191 1.00 12.80 ? 355 ASP A CG  1 
ATOM 2773 O OD1 . ASP A 1 371 ? 151.001 188.190 142.365 1.00 12.80 ? 355 ASP A OD1 1 
ATOM 2774 O OD2 . ASP A 1 371 ? 149.573 189.832 142.073 1.00 12.80 ? 355 ASP A OD2 1 
ATOM 2775 N N   . ASN A 1 372 ? 154.080 192.115 140.029 1.00 9.86  ? 356 ASN A N   1 
ATOM 2776 C CA  . ASN A 1 372 ? 155.311 192.899 139.936 1.00 9.86  ? 356 ASN A CA  1 
ATOM 2777 C C   . ASN A 1 372 ? 155.382 193.876 141.110 1.00 9.86  ? 356 ASN A C   1 
ATOM 2778 O O   . ASN A 1 372 ? 155.277 195.096 140.970 1.00 9.86  ? 356 ASN A O   1 
ATOM 2779 C CB  . ASN A 1 372 ? 155.377 193.619 138.597 1.00 9.86  ? 356 ASN A CB  1 
ATOM 2780 C CG  . ASN A 1 372 ? 155.231 192.672 137.426 1.00 9.86  ? 356 ASN A CG  1 
ATOM 2781 O OD1 . ASN A 1 372 ? 154.920 191.494 137.602 1.00 9.86  ? 356 ASN A OD1 1 
ATOM 2782 N ND2 . ASN A 1 372 ? 155.451 193.182 136.222 1.00 9.86  ? 356 ASN A ND2 1 
ATOM 2783 N N   . VAL A 1 373 ? 155.563 193.304 142.297 1.00 9.50  ? 357 VAL A N   1 
ATOM 2784 C CA  . VAL A 1 373 ? 155.633 194.061 143.541 1.00 9.50  ? 357 VAL A CA  1 
ATOM 2785 C C   . VAL A 1 373 ? 156.735 193.474 144.409 1.00 9.50  ? 357 VAL A C   1 
ATOM 2786 O O   . VAL A 1 373 ? 156.894 192.251 144.485 1.00 9.50  ? 357 VAL A O   1 
ATOM 2787 C CB  . VAL A 1 373 ? 154.285 194.051 144.293 1.00 9.50  ? 357 VAL A CB  1 
ATOM 2788 C CG1 . VAL A 1 373 ? 153.304 195.025 143.655 1.00 9.50  ? 357 VAL A CG1 1 
ATOM 2789 C CG2 . VAL A 1 373 ? 153.706 192.647 144.321 1.00 9.50  ? 357 VAL A CG2 1 
ATOM 2790 N N   . TRP A 1 374 ? 157.499 194.345 145.059 1.00 9.08  ? 358 TRP A N   1 
ATOM 2791 C CA  . TRP A 1 374 ? 158.550 193.934 145.978 1.00 9.08  ? 358 TRP A CA  1 
ATOM 2792 C C   . TRP A 1 374 ? 158.080 194.024 147.425 1.00 9.08  ? 358 TRP A C   1 
ATOM 2793 O O   . TRP A 1 374 ? 157.229 194.838 147.790 1.00 9.08  ? 358 TRP A O   1 
ATOM 2794 C CB  . TRP A 1 374 ? 159.812 194.779 145.781 1.00 9.08  ? 358 TRP A CB  1 
ATOM 2795 C CG  . TRP A 1 374 ? 160.350 194.736 144.399 1.00 9.08  ? 358 TRP A CG  1 
ATOM 2796 C CD1 . TRP A 1 374 ? 159.871 195.393 143.305 1.00 9.08  ? 358 TRP A CD1 1 
ATOM 2797 C CD2 . TRP A 1 374 ? 161.472 193.974 143.951 1.00 9.08  ? 358 TRP A CD2 1 
ATOM 2798 N NE1 . TRP A 1 374 ? 160.635 195.092 142.201 1.00 9.08  ? 358 TRP A NE1 1 
ATOM 2799 C CE2 . TRP A 1 374 ? 161.624 194.221 142.575 1.00 9.08  ? 358 TRP A CE2 1 
ATOM 2800 C CE3 . TRP A 1 374 ? 162.365 193.107 144.582 1.00 9.08  ? 358 TRP A CE3 1 
ATOM 2801 C CZ2 . TRP A 1 374 ? 162.629 193.635 141.825 1.00 9.08  ? 358 TRP A CZ2 1 
ATOM 2802 C CZ3 . TRP A 1 374 ? 163.362 192.532 143.838 1.00 9.08  ? 358 TRP A CZ3 1 
ATOM 2803 C CH2 . TRP A 1 374 ? 163.483 192.789 142.475 1.00 9.08  ? 358 TRP A CH2 1 
ATOM 2804 N N   . THR A 1 375 ? 158.664 193.167 148.254 1.00 6.69  ? 359 THR A N   1 
ATOM 2805 C CA  . THR A 1 375 ? 158.408 193.151 149.688 1.00 6.69  ? 359 THR A CA  1 
ATOM 2806 C C   . THR A 1 375 ? 159.759 193.074 150.391 1.00 6.69  ? 359 THR A C   1 
ATOM 2807 O O   . THR A 1 375 ? 160.802 193.330 149.782 1.00 6.69  ? 359 THR A O   1 
ATOM 2808 C CB  . THR A 1 375 ? 157.486 191.980 150.080 1.00 6.69  ? 359 THR A CB  1 
ATOM 2809 O OG1 . THR A 1 375 ? 158.279 190.819 150.349 1.00 6.69  ? 359 THR A OG1 1 
ATOM 2810 C CG2 . THR A 1 375 ? 156.487 191.656 148.975 1.00 6.69  ? 359 THR A CG2 1 
ATOM 2811 N N   . GLU A 1 376 ? 159.743 192.746 151.679 1.00 4.38  ? 360 GLU A N   1 
ATOM 2812 C CA  . GLU A 1 376 ? 160.972 192.514 152.420 1.00 4.38  ? 360 GLU A CA  1 
ATOM 2813 C C   . GLU A 1 376 ? 160.736 191.365 153.387 1.00 4.38  ? 360 GLU A C   1 
ATOM 2814 O O   . GLU A 1 376 ? 159.612 191.147 153.846 1.00 4.38  ? 360 GLU A O   1 
ATOM 2815 C CB  . GLU A 1 376 ? 161.434 193.774 153.164 1.00 4.38  ? 360 GLU A CB  1 
ATOM 2816 C CG  . GLU A 1 376 ? 162.788 193.639 153.846 1.00 4.38  ? 360 GLU A CG  1 
ATOM 2817 C CD  . GLU A 1 376 ? 163.677 194.847 153.627 1.00 4.38  ? 360 GLU A CD  1 
ATOM 2818 O OE1 . GLU A 1 376 ? 163.407 195.621 152.685 1.00 4.38  ? 360 GLU A OE1 1 
ATOM 2819 O OE2 . GLU A 1 376 ? 164.649 195.019 154.392 1.00 4.38  ? 360 GLU A OE2 1 
ATOM 2820 N N   . THR A 1 377 ? 161.800 190.624 153.685 1.00 4.13  ? 361 THR A N   1 
ATOM 2821 C CA  . THR A 1 377 ? 161.696 189.446 154.532 1.00 4.13  ? 361 THR A CA  1 
ATOM 2822 C C   . THR A 1 377 ? 162.861 189.469 155.522 1.00 4.13  ? 361 THR A C   1 
ATOM 2823 O O   . THR A 1 377 ? 163.585 190.463 155.634 1.00 4.13  ? 361 THR A O   1 
ATOM 2824 C CB  . THR A 1 377 ? 161.656 188.177 153.669 1.00 4.13  ? 361 THR A CB  1 
ATOM 2825 O OG1 . THR A 1 377 ? 160.913 188.442 152.474 1.00 4.13  ? 361 THR A OG1 1 
ATOM 2826 C CG2 . THR A 1 377 ? 160.947 187.059 154.409 1.00 4.13  ? 361 THR A CG2 1 
ATOM 2827 N N   . THR A 1 378 ? 163.035 188.365 156.247 1.00 6.47  ? 362 THR A N   1 
ATOM 2828 C CA  . THR A 1 378 ? 164.022 188.297 157.317 1.00 6.47  ? 362 THR A CA  1 
ATOM 2829 C C   . THR A 1 378 ? 165.431 188.496 156.773 1.00 6.47  ? 362 THR A C   1 
ATOM 2830 O O   . THR A 1 378 ? 165.814 187.909 155.758 1.00 6.47  ? 362 THR A O   1 
ATOM 2831 C CB  . THR A 1 378 ? 163.919 186.950 158.038 1.00 6.47  ? 362 THR A CB  1 
ATOM 2832 O OG1 . THR A 1 378 ? 162.694 186.895 158.780 1.00 6.47  ? 362 THR A OG1 1 
ATOM 2833 C CG2 . THR A 1 378 ? 165.089 186.752 158.994 1.00 6.47  ? 362 THR A CG2 1 
ATOM 2834 N N   . GLN A 1 379 ? 166.204 189.329 157.461 1.00 9.13  ? 363 GLN A N   1 
ATOM 2835 C CA  . GLN A 1 379 ? 167.558 189.659 157.049 1.00 9.13  ? 363 GLN A CA  1 
ATOM 2836 C C   . GLN A 1 379 ? 168.518 188.516 157.361 1.00 9.13  ? 363 GLN A C   1 
ATOM 2837 O O   . GLN A 1 379 ? 168.227 187.621 158.157 1.00 9.13  ? 363 GLN A O   1 
ATOM 2838 C CB  . GLN A 1 379 ? 168.030 190.940 157.739 1.00 9.13  ? 363 GLN A CB  1 
ATOM 2839 C CG  . GLN A 1 379 ? 167.051 192.096 157.638 1.00 9.13  ? 363 GLN A CG  1 
ATOM 2840 C CD  . GLN A 1 379 ? 167.627 193.392 158.170 1.00 9.13  ? 363 GLN A CD  1 
ATOM 2841 O OE1 . GLN A 1 379 ? 167.375 194.467 157.625 1.00 9.13  ? 363 GLN A OE1 1 
ATOM 2842 N NE2 . GLN A 1 379 ? 168.408 193.298 159.239 1.00 9.13  ? 363 GLN A NE2 1 
ATOM 2843 N N   . LEU A 1 380 ? 169.678 188.560 156.712 1.00 10.38 ? 364 LEU A N   1 
ATOM 2844 C CA  . LEU A 1 380 ? 170.721 187.575 156.953 1.00 10.38 ? 364 LEU A CA  1 
ATOM 2845 C C   . LEU A 1 380 ? 171.412 187.841 158.285 1.00 10.38 ? 364 LEU A C   1 
ATOM 2846 O O   . LEU A 1 380 ? 171.430 188.968 158.788 1.00 10.38 ? 364 LEU A O   1 
ATOM 2847 C CB  . LEU A 1 380 ? 171.748 187.601 155.822 1.00 10.38 ? 364 LEU A CB  1 
ATOM 2848 C CG  . LEU A 1 380 ? 171.251 187.254 154.418 1.00 10.38 ? 364 LEU A CG  1 
ATOM 2849 C CD1 . LEU A 1 380 ? 172.305 187.608 153.386 1.00 10.38 ? 364 LEU A CD1 1 
ATOM 2850 C CD2 . LEU A 1 380 ? 170.885 185.784 154.326 1.00 10.38 ? 364 LEU A CD2 1 
ATOM 2851 N N   . GLU A 1 381 ? 171.984 186.784 158.864 1.00 15.36 ? 365 GLU A N   1 
ATOM 2852 C CA  . GLU A 1 381 ? 172.747 186.947 160.098 1.00 15.36 ? 365 GLU A CA  1 
ATOM 2853 C C   . GLU A 1 381 ? 174.038 187.715 159.845 1.00 15.36 ? 365 GLU A C   1 
ATOM 2854 O O   . GLU A 1 381 ? 174.403 188.608 160.619 1.00 15.36 ? 365 GLU A O   1 
ATOM 2855 C CB  . GLU A 1 381 ? 173.043 185.585 160.724 1.00 15.36 ? 365 GLU A CB  1 
ATOM 2856 C CG  . GLU A 1 381 ? 171.910 185.031 161.572 1.00 15.36 ? 365 GLU A CG  1 
ATOM 2857 C CD  . GLU A 1 381 ? 172.390 184.023 162.597 1.00 15.36 ? 365 GLU A CD  1 
ATOM 2858 O OE1 . GLU A 1 381 ? 173.615 183.944 162.826 1.00 15.36 ? 365 GLU A OE1 1 
ATOM 2859 O OE2 . GLU A 1 381 ? 171.543 183.308 163.173 1.00 15.36 ? 365 GLU A OE2 1 
ATOM 2860 N N   . VAL A 1 382 ? 174.744 187.383 158.767 1.00 13.82 ? 366 VAL A N   1 
ATOM 2861 C CA  . VAL A 1 382 ? 175.994 188.038 158.405 1.00 13.82 ? 366 VAL A CA  1 
ATOM 2862 C C   . VAL A 1 382 ? 175.870 188.551 156.978 1.00 13.82 ? 366 VAL A C   1 
ATOM 2863 O O   . VAL A 1 382 ? 175.506 187.793 156.072 1.00 13.82 ? 366 VAL A O   1 
ATOM 2864 C CB  . VAL A 1 382 ? 177.199 187.086 158.534 1.00 13.82 ? 366 VAL A CB  1 
ATOM 2865 C CG1 . VAL A 1 382 ? 178.452 187.736 157.974 1.00 13.82 ? 366 VAL A CG1 1 
ATOM 2866 C CG2 . VAL A 1 382 ? 177.402 186.684 159.986 1.00 13.82 ? 366 VAL A CG2 1 
ATOM 2867 N N   . ALA A 1 383 ? 176.172 189.831 156.779 1.00 11.81 ? 367 ALA A N   1 
ATOM 2868 C CA  . ALA A 1 383 ? 176.078 190.437 155.458 1.00 11.81 ? 367 ALA A CA  1 
ATOM 2869 C C   . ALA A 1 383 ? 177.266 190.019 154.601 1.00 11.81 ? 367 ALA A C   1 
ATOM 2870 O O   . ALA A 1 383 ? 178.415 190.066 155.050 1.00 11.81 ? 367 ALA A O   1 
ATOM 2871 C CB  . ALA A 1 383 ? 176.017 191.959 155.572 1.00 11.81 ? 367 ALA A CB  1 
ATOM 2872 N N   . VAL A 1 384 ? 176.985 189.608 153.366 1.00 6.98  ? 368 VAL A N   1 
ATOM 2873 C CA  . VAL A 1 384 ? 178.014 189.216 152.412 1.00 6.98  ? 368 VAL A CA  1 
ATOM 2874 C C   . VAL A 1 384 ? 177.750 189.920 151.090 1.00 6.98  ? 368 VAL A C   1 
ATOM 2875 O O   . VAL A 1 384 ? 176.616 190.299 150.780 1.00 6.98  ? 368 VAL A O   1 
ATOM 2876 C CB  . VAL A 1 384 ? 178.066 187.685 152.210 1.00 6.98  ? 368 VAL A CB  1 
ATOM 2877 C CG1 . VAL A 1 384 ? 178.555 186.996 153.472 1.00 6.98  ? 368 VAL A CG1 1 
ATOM 2878 C CG2 . VAL A 1 384 ? 176.701 187.157 151.803 1.00 6.98  ? 368 VAL A CG2 1 
ATOM 2879 N N   . SER A 1 385 ? 178.811 190.095 150.307 1.00 6.70  ? 369 SER A N   1 
ATOM 2880 C CA  . SER A 1 385 ? 178.726 190.723 148.997 1.00 6.70  ? 369 SER A CA  1 
ATOM 2881 C C   . SER A 1 385 ? 179.499 189.891 147.986 1.00 6.70  ? 369 SER A C   1 
ATOM 2882 O O   . SER A 1 385 ? 180.560 189.345 148.302 1.00 6.70  ? 369 SER A O   1 
ATOM 2883 C CB  . SER A 1 385 ? 179.274 192.152 149.025 1.00 6.70  ? 369 SER A CB  1 
ATOM 2884 O OG  . SER A 1 385 ? 180.651 192.160 149.355 1.00 6.70  ? 369 SER A OG  1 
ATOM 2885 N N   . GLY A 1 386 ? 178.970 189.807 146.770 1.00 5.40  ? 370 GLY A N   1 
ATOM 2886 C CA  . GLY A 1 386 ? 179.610 189.011 145.734 1.00 5.40  ? 370 GLY A CA  1 
ATOM 2887 C C   . GLY A 1 386 ? 179.661 187.533 146.050 1.00 5.40  ? 370 GLY A C   1 
ATOM 2888 O O   . GLY A 1 386 ? 180.676 186.877 145.788 1.00 5.40  ? 370 GLY A O   1 
ATOM 2889 N N   . ALA A 1 387 ? 178.584 186.991 146.610 1.00 4.28  ? 371 ALA A N   1 
ATOM 2890 C CA  . ALA A 1 387 ? 178.539 185.589 146.999 1.00 4.28  ? 371 ALA A CA  1 
ATOM 2891 C C   . ALA A 1 387 ? 178.181 184.727 145.789 1.00 4.28  ? 371 ALA A C   1 
ATOM 2892 O O   . ALA A 1 387 ? 178.200 185.178 144.641 1.00 4.28  ? 371 ALA A O   1 
ATOM 2893 C CB  . ALA A 1 387 ? 177.557 185.396 148.150 1.00 4.28  ? 371 ALA A CB  1 
ATOM 2894 N N   . ALA A 1 388 ? 177.857 183.462 146.041 1.00 0.93  ? 372 ALA A N   1 
ATOM 2895 C CA  . ALA A 1 388 ? 177.440 182.524 145.008 1.00 0.93  ? 372 ALA A CA  1 
ATOM 2896 C C   . ALA A 1 388 ? 175.999 182.114 145.264 1.00 0.93  ? 372 ALA A C   1 
ATOM 2897 O O   . ALA A 1 388 ? 175.637 181.784 146.398 1.00 0.93  ? 372 ALA A O   1 
ATOM 2898 C CB  . ALA A 1 388 ? 178.347 181.293 144.983 1.00 0.93  ? 372 ALA A CB  1 
ATOM 2899 N N   . GLY A 1 389 ? 175.182 182.132 144.216 1.00 0.12  ? 373 GLY A N   1 
ATOM 2900 C CA  . GLY A 1 389 ? 173.779 181.799 144.361 1.00 0.12  ? 373 GLY A CA  1 
ATOM 2901 C C   . GLY A 1 389 ? 173.444 180.366 144.005 1.00 0.12  ? 373 GLY A C   1 
ATOM 2902 O O   . GLY A 1 389 ? 173.437 179.997 142.828 1.00 0.12  ? 373 GLY A O   1 
ATOM 2903 N N   . ALA A 1 390 ? 173.156 179.550 145.016 1.00 0.40  ? 374 ALA A N   1 
ATOM 2904 C CA  . ALA A 1 390 ? 172.773 178.158 144.828 1.00 0.40  ? 374 ALA A CA  1 
ATOM 2905 C C   . ALA A 1 390 ? 171.385 177.944 145.410 1.00 0.40  ? 374 ALA A C   1 
ATOM 2906 O O   . ALA A 1 390 ? 171.100 178.393 146.524 1.00 0.40  ? 374 ALA A O   1 
ATOM 2907 C CB  . ALA A 1 390 ? 173.779 177.212 145.487 1.00 0.40  ? 374 ALA A CB  1 
ATOM 2908 N N   . ASN A 1 391 ? 170.531 177.253 144.661 1.00 2.11  ? 375 ASN A N   1 
ATOM 2909 C CA  . ASN A 1 391 ? 169.132 177.055 145.017 1.00 2.11  ? 375 ASN A CA  1 
ATOM 2910 C C   . ASN A 1 391 ? 168.808 175.571 145.151 1.00 2.11  ? 375 ASN A C   1 
ATOM 2911 O O   . ASN A 1 391 ? 167.810 175.081 144.619 1.00 2.11  ? 375 ASN A O   1 
ATOM 2912 C CB  . ASN A 1 391 ? 168.218 177.722 143.992 1.00 2.11  ? 375 ASN A CB  1 
ATOM 2913 C CG  . ASN A 1 391 ? 166.760 177.687 144.398 1.00 2.11  ? 375 ASN A CG  1 
ATOM 2914 O OD1 . ASN A 1 391 ? 166.436 177.650 145.583 1.00 2.11  ? 375 ASN A OD1 1 
ATOM 2915 N ND2 . ASN A 1 391 ? 165.873 177.680 143.414 1.00 2.11  ? 375 ASN A ND2 1 
ATOM 2916 N N   . LEU A 1 392 ? 169.665 174.829 145.849 1.00 4.68  ? 376 LEU A N   1 
ATOM 2917 C CA  . LEU A 1 392 ? 169.439 173.401 146.023 1.00 4.68  ? 376 LEU A CA  1 
ATOM 2918 C C   . LEU A 1 392 ? 168.157 173.169 146.813 1.00 4.68  ? 376 LEU A C   1 
ATOM 2919 O O   . LEU A 1 392 ? 167.945 173.779 147.865 1.00 4.68  ? 376 LEU A O   1 
ATOM 2920 C CB  . LEU A 1 392 ? 170.638 172.766 146.733 1.00 4.68  ? 376 LEU A CB  1 
ATOM 2921 C CG  . LEU A 1 392 ? 170.631 171.284 147.132 1.00 4.68  ? 376 LEU A CG  1 
ATOM 2922 C CD1 . LEU A 1 392 ? 169.986 171.046 148.498 1.00 4.68  ? 376 LEU A CD1 1 
ATOM 2923 C CD2 . LEU A 1 392 ? 169.987 170.415 146.055 1.00 4.68  ? 376 LEU A CD2 1 
ATOM 2924 N N   . ASN A 1 393 ? 167.307 172.281 146.301 1.00 8.43  ? 377 ASN A N   1 
ATOM 2925 C CA  . ASN A 1 393 ? 166.021 171.924 146.920 1.00 8.43  ? 377 ASN A CA  1 
ATOM 2926 C C   . ASN A 1 393 ? 165.192 173.204 147.019 1.00 8.43  ? 377 ASN A C   1 
ATOM 2927 O O   . ASN A 1 393 ? 165.028 173.898 146.003 1.00 8.43  ? 377 ASN A O   1 
ATOM 2928 C CB  . ASN A 1 393 ? 166.277 171.197 148.236 1.00 8.43  ? 377 ASN A CB  1 
ATOM 2929 C CG  . ASN A 1 393 ? 165.041 170.500 148.769 1.00 8.43  ? 377 ASN A CG  1 
ATOM 2930 O OD1 . ASN A 1 393 ? 163.916 170.837 148.403 1.00 8.43  ? 377 ASN A OD1 1 
ATOM 2931 N ND2 . ASN A 1 393 ? 165.246 169.523 149.643 1.00 8.43  ? 377 ASN A ND2 1 
ATOM 2932 N N   . GLY A 1 394 ? 164.654 173.551 148.185 1.00 4.93  ? 378 GLY A N   1 
ATOM 2933 C CA  . GLY A 1 394 ? 163.930 174.795 148.350 1.00 4.93  ? 378 GLY A CA  1 
ATOM 2934 C C   . GLY A 1 394 ? 164.632 175.743 149.299 1.00 4.93  ? 378 GLY A C   1 
ATOM 2935 O O   . GLY A 1 394 ? 164.035 176.711 149.778 1.00 4.93  ? 378 GLY A O   1 
ATOM 2936 N N   . ILE A 1 395 ? 165.905 175.474 149.573 1.00 2.52  ? 379 ILE A N   1 
ATOM 2937 C CA  . ILE A 1 395 ? 166.707 176.256 150.505 1.00 2.52  ? 379 ILE A CA  1 
ATOM 2938 C C   . ILE A 1 395 ? 167.760 177.014 149.712 1.00 2.52  ? 379 ILE A C   1 
ATOM 2939 O O   . ILE A 1 395 ? 168.493 176.416 148.917 1.00 2.52  ? 379 ILE A O   1 
ATOM 2940 C CB  . ILE A 1 395 ? 167.365 175.364 151.572 1.00 2.52  ? 379 ILE A CB  1 
ATOM 2941 C CG1 . ILE A 1 395 ? 166.299 174.630 152.385 1.00 2.52  ? 379 ILE A CG1 1 
ATOM 2942 C CG2 . ILE A 1 395 ? 168.258 176.189 152.480 1.00 2.52  ? 379 ILE A CG2 1 
ATOM 2943 C CD1 . ILE A 1 395 ? 166.865 173.650 153.388 1.00 2.52  ? 379 ILE A CD1 1 
ATOM 2944 N N   . ILE A 1 396 ? 167.836 178.322 149.931 1.00 1.49  ? 380 ILE A N   1 
ATOM 2945 C CA  . ILE A 1 396 ? 168.776 179.179 149.220 1.00 1.49  ? 380 ILE A CA  1 
ATOM 2946 C C   . ILE A 1 396 ? 170.105 179.158 149.962 1.00 1.49  ? 380 ILE A C   1 
ATOM 2947 O O   . ILE A 1 396 ? 170.168 179.494 151.149 1.00 1.49  ? 380 ILE A O   1 
ATOM 2948 C CB  . ILE A 1 396 ? 168.236 180.610 149.096 1.00 1.49  ? 380 ILE A CB  1 
ATOM 2949 C CG1 . ILE A 1 396 ? 166.866 180.600 148.422 1.00 1.49  ? 380 ILE A CG1 1 
ATOM 2950 C CG2 . ILE A 1 396 ? 169.200 181.474 148.310 1.00 1.49  ? 380 ILE A CG2 1 
ATOM 2951 C CD1 . ILE A 1 396 ? 166.288 181.973 148.203 1.00 1.49  ? 380 ILE A CD1 1 
ATOM 2952 N N   . TYR A 1 397 ? 171.167 178.769 149.263 1.00 1.30  ? 381 TYR A N   1 
ATOM 2953 C CA  . TYR A 1 397 ? 172.500 178.677 149.843 1.00 1.30  ? 381 TYR A CA  1 
ATOM 2954 C C   . TYR A 1 397 ? 173.361 179.829 149.346 1.00 1.30  ? 381 TYR A C   1 
ATOM 2955 O O   . TYR A 1 397 ? 173.419 180.092 148.140 1.00 1.30  ? 381 TYR A O   1 
ATOM 2956 C CB  . TYR A 1 397 ? 173.158 177.342 149.491 1.00 1.30  ? 381 TYR A CB  1 
ATOM 2957 C CG  . TYR A 1 397 ? 172.662 176.180 150.316 1.00 1.30  ? 381 TYR A CG  1 
ATOM 2958 C CD1 . TYR A 1 397 ? 171.429 175.602 150.061 1.00 1.30  ? 381 TYR A CD1 1 
ATOM 2959 C CD2 . TYR A 1 397 ? 173.428 175.661 151.348 1.00 1.30  ? 381 TYR A CD2 1 
ATOM 2960 C CE1 . TYR A 1 397 ? 170.970 174.540 150.813 1.00 1.30  ? 381 TYR A CE1 1 
ATOM 2961 C CE2 . TYR A 1 397 ? 172.978 174.599 152.104 1.00 1.30  ? 381 TYR A CE2 1 
ATOM 2962 C CZ  . TYR A 1 397 ? 171.748 174.043 151.833 1.00 1.30  ? 381 TYR A CZ  1 
ATOM 2963 O OH  . TYR A 1 397 ? 171.293 172.985 152.583 1.00 1.30  ? 381 TYR A OH  1 
ATOM 2964 N N   . LEU A 1 398 ? 174.024 180.512 150.274 1.00 2.28  ? 382 LEU A N   1 
ATOM 2965 C CA  . LEU A 1 398 ? 174.970 181.575 149.955 1.00 2.28  ? 382 LEU A CA  1 
ATOM 2966 C C   . LEU A 1 398 ? 176.371 181.065 150.265 1.00 2.28  ? 382 LEU A C   1 
ATOM 2967 O O   . LEU A 1 398 ? 176.692 180.781 151.424 1.00 2.28  ? 382 LEU A O   1 
ATOM 2968 C CB  . LEU A 1 398 ? 174.656 182.845 150.740 1.00 2.28  ? 382 LEU A CB  1 
ATOM 2969 C CG  . LEU A 1 398 ? 173.313 183.501 150.430 1.00 2.28  ? 382 LEU A CG  1 
ATOM 2970 C CD1 . LEU A 1 398 ? 173.208 184.844 151.121 1.00 2.28  ? 382 LEU A CD1 1 
ATOM 2971 C CD2 . LEU A 1 398 ? 173.134 183.655 148.932 1.00 2.28  ? 382 LEU A CD2 1 
ATOM 2972 N N   . LEU A 1 399 ? 177.201 180.954 149.234 1.00 1.97  ? 383 LEU A N   1 
ATOM 2973 C CA  . LEU A 1 399 ? 178.548 180.416 149.356 1.00 1.97  ? 383 LEU A CA  1 
ATOM 2974 C C   . LEU A 1 399 ? 179.563 181.515 149.083 1.00 1.97  ? 383 LEU A C   1 
ATOM 2975 O O   . LEU A 1 399 ? 179.391 182.307 148.150 1.00 1.97  ? 383 LEU A O   1 
ATOM 2976 C CB  . LEU A 1 399 ? 178.759 179.251 148.388 1.00 1.97  ? 383 LEU A CB  1 
ATOM 2977 C CG  . LEU A 1 399 ? 177.628 178.228 148.318 1.00 1.97  ? 383 LEU A CG  1 
ATOM 2978 C CD1 . LEU A 1 399 ? 177.814 177.312 147.122 1.00 1.97  ? 383 LEU A CD1 1 
ATOM 2979 C CD2 . LEU A 1 399 ? 177.554 177.426 149.603 1.00 1.97  ? 383 LEU A CD2 1 
ATOM 2980 N N   . GLY A 1 400 ? 180.613 181.563 149.898 1.00 3.27  ? 384 GLY A N   1 
ATOM 2981 C CA  . GLY A 1 400 ? 181.682 182.511 149.668 1.00 3.27  ? 384 GLY A CA  1 
ATOM 2982 C C   . GLY A 1 400 ? 181.254 183.949 149.909 1.00 3.27  ? 384 GLY A C   1 
ATOM 2983 O O   . GLY A 1 400 ? 180.292 184.242 150.622 1.00 3.27  ? 384 GLY A O   1 
ATOM 2984 N N   . GLY A 1 401 ? 181.995 184.855 149.290 1.00 6.62  ? 385 GLY A N   1 
ATOM 2985 C CA  . GLY A 1 401 ? 181.756 186.276 149.413 1.00 6.62  ? 385 GLY A CA  1 
ATOM 2986 C C   . GLY A 1 401 ? 182.855 186.961 150.205 1.00 6.62  ? 385 GLY A C   1 
ATOM 2987 O O   . GLY A 1 401 ? 183.911 186.391 150.494 1.00 6.62  ? 385 GLY A O   1 
ATOM 2988 N N   . GLU A 1 402 ? 182.586 188.215 150.559 1.00 15.09 ? 386 GLU A N   1 
ATOM 2989 C CA  . GLU A 1 402 ? 183.518 189.035 151.317 1.00 15.09 ? 386 GLU A CA  1 
ATOM 2990 C C   . GLU A 1 402 ? 182.813 189.616 152.533 1.00 15.09 ? 386 GLU A C   1 
ATOM 2991 O O   . GLU A 1 402 ? 181.603 189.854 152.514 1.00 15.09 ? 386 GLU A O   1 
ATOM 2992 C CB  . GLU A 1 402 ? 184.100 190.164 150.458 1.00 15.09 ? 386 GLU A CB  1 
ATOM 2993 C CG  . GLU A 1 402 ? 184.816 189.683 149.207 1.00 15.09 ? 386 GLU A CG  1 
ATOM 2994 C CD  . GLU A 1 402 ? 185.116 190.808 148.239 1.00 15.09 ? 386 GLU A CD  1 
ATOM 2995 O OE1 . GLU A 1 402 ? 184.659 191.943 148.487 1.00 15.09 ? 386 GLU A OE1 1 
ATOM 2996 O OE2 . GLU A 1 402 ? 185.809 190.558 147.231 1.00 15.09 ? 386 GLU A OE2 1 
ATOM 2997 N N   . GLU A 1 403 ? 183.585 189.843 153.593 1.00 23.49 ? 387 GLU A N   1 
ATOM 2998 C CA  . GLU A 1 403 ? 183.035 190.357 154.839 1.00 23.49 ? 387 GLU A CA  1 
ATOM 2999 C C   . GLU A 1 403 ? 184.162 190.988 155.644 1.00 23.49 ? 387 GLU A C   1 
ATOM 3000 O O   . GLU A 1 403 ? 185.256 190.425 155.733 1.00 23.49 ? 387 GLU A O   1 
ATOM 3001 C CB  . GLU A 1 403 ? 182.353 189.239 155.638 1.00 23.49 ? 387 GLU A CB  1 
ATOM 3002 C CG  . GLU A 1 403 ? 181.273 189.707 156.601 1.00 23.49 ? 387 GLU A CG  1 
ATOM 3003 C CD  . GLU A 1 403 ? 181.829 190.420 157.814 1.00 23.49 ? 387 GLU A CD  1 
ATOM 3004 O OE1 . GLU A 1 403 ? 181.246 191.447 158.221 1.00 23.49 ? 387 GLU A OE1 1 
ATOM 3005 O OE2 . GLU A 1 403 ? 182.848 189.951 158.364 1.00 23.49 ? 387 GLU A OE2 1 
ATOM 3006 N N   . ASN A 1 404 ? 183.888 192.155 156.224 1.00 23.83 ? 388 ASN A N   1 
ATOM 3007 C CA  . ASN A 1 404 ? 184.869 192.872 157.029 1.00 23.83 ? 388 ASN A CA  1 
ATOM 3008 C C   . ASN A 1 404 ? 184.738 192.447 158.487 1.00 23.83 ? 388 ASN A C   1 
ATOM 3009 O O   . ASN A 1 404 ? 183.663 192.575 159.083 1.00 23.83 ? 388 ASN A O   1 
ATOM 3010 C CB  . ASN A 1 404 ? 184.691 194.384 156.881 1.00 23.83 ? 388 ASN A CB  1 
ATOM 3011 C CG  . ASN A 1 404 ? 183.268 194.837 157.154 1.00 23.83 ? 388 ASN A CG  1 
ATOM 3012 O OD1 . ASN A 1 404 ? 182.338 194.031 157.171 1.00 23.83 ? 388 ASN A OD1 1 
ATOM 3013 N ND2 . ASN A 1 404 ? 183.094 196.135 157.372 1.00 23.83 ? 388 ASN A ND2 1 
ATOM 3014 N N   . ASP A 1 405 ? 185.831 191.946 159.063 1.00 24.85 ? 389 ASP A N   1 
ATOM 3015 C CA  . ASP A 1 405 ? 185.758 191.390 160.414 1.00 24.85 ? 389 ASP A CA  1 
ATOM 3016 C C   . ASP A 1 405 ? 185.817 192.487 161.474 1.00 24.85 ? 389 ASP A C   1 
ATOM 3017 O O   . ASP A 1 405 ? 184.841 192.721 162.194 1.00 24.85 ? 389 ASP A O   1 
ATOM 3018 C CB  . ASP A 1 405 ? 186.883 190.370 160.619 1.00 24.85 ? 389 ASP A CB  1 
ATOM 3019 C CG  . ASP A 1 405 ? 188.160 190.760 159.903 1.00 24.85 ? 389 ASP A CG  1 
ATOM 3020 O OD1 . ASP A 1 405 ? 188.223 191.888 159.368 1.00 24.85 ? 389 ASP A OD1 1 
ATOM 3021 O OD2 . ASP A 1 405 ? 189.102 189.941 159.873 1.00 24.85 ? 389 ASP A OD2 1 
ATOM 3022 N N   . LEU A 1 406 ? 186.950 193.169 161.586 1.00 21.34 ? 390 LEU A N   1 
ATOM 3023 C CA  . LEU A 1 406 ? 187.022 194.244 162.570 1.00 21.34 ? 390 LEU A CA  1 
ATOM 3024 C C   . LEU A 1 406 ? 187.574 195.550 162.018 1.00 21.34 ? 390 LEU A C   1 
ATOM 3025 O O   . LEU A 1 406 ? 187.056 196.617 162.358 1.00 21.34 ? 390 LEU A O   1 
ATOM 3026 C CB  . LEU A 1 406 ? 187.872 193.795 163.770 1.00 21.34 ? 390 LEU A CB  1 
ATOM 3027 C CG  . LEU A 1 406 ? 187.207 192.834 164.757 1.00 21.34 ? 390 LEU A CG  1 
ATOM 3028 C CD1 . LEU A 1 406 ? 188.160 192.486 165.891 1.00 21.34 ? 390 LEU A CD1 1 
ATOM 3029 C CD2 . LEU A 1 406 ? 185.917 193.428 165.300 1.00 21.34 ? 390 LEU A CD2 1 
ATOM 3030 N N   . ASP A 1 407 ? 188.602 195.499 161.179 1.00 25.58 ? 391 ASP A N   1 
ATOM 3031 C CA  . ASP A 1 407 ? 189.301 196.714 160.754 1.00 25.58 ? 391 ASP A CA  1 
ATOM 3032 C C   . ASP A 1 407 ? 188.775 197.245 159.427 1.00 25.58 ? 391 ASP A C   1 
ATOM 3033 O O   . ASP A 1 407 ? 189.551 197.556 158.523 1.00 25.58 ? 391 ASP A O   1 
ATOM 3034 C CB  . ASP A 1 407 ? 190.799 196.450 160.676 1.00 25.58 ? 391 ASP A CB  1 
ATOM 3035 C CG  . ASP A 1 407 ? 191.127 195.172 159.929 1.00 25.58 ? 391 ASP A CG  1 
ATOM 3036 O OD1 . ASP A 1 407 ? 190.207 194.355 159.714 1.00 25.58 ? 391 ASP A OD1 1 
ATOM 3037 O OD2 . ASP A 1 407 ? 192.304 194.984 159.557 1.00 25.58 ? 391 ASP A OD2 1 
ATOM 3038 N N   . PHE A 1 408 ? 187.451 197.355 159.293 1.00 28.07 ? 392 PHE A N   1 
ATOM 3039 C CA  . PHE A 1 408 ? 186.809 198.075 158.195 1.00 28.07 ? 392 PHE A CA  1 
ATOM 3040 C C   . PHE A 1 408 ? 187.221 197.528 156.824 1.00 28.07 ? 392 PHE A C   1 
ATOM 3041 O O   . PHE A 1 408 ? 186.797 198.042 155.784 1.00 28.07 ? 392 PHE A O   1 
ATOM 3042 C CB  . PHE A 1 408 ? 187.124 199.575 158.344 1.00 28.07 ? 392 PHE A CB  1 
ATOM 3043 C CG  . PHE A 1 408 ? 186.769 200.415 157.147 1.00 28.07 ? 392 PHE A CG  1 
ATOM 3044 C CD1 . PHE A 1 408 ? 187.753 200.856 156.275 1.00 28.07 ? 392 PHE A CD1 1 
ATOM 3045 C CD2 . PHE A 1 408 ? 185.453 200.762 156.895 1.00 28.07 ? 392 PHE A CD2 1 
ATOM 3046 C CE1 . PHE A 1 408 ? 187.428 201.626 155.174 1.00 28.07 ? 392 PHE A CE1 1 
ATOM 3047 C CE2 . PHE A 1 408 ? 185.122 201.533 155.796 1.00 28.07 ? 392 PHE A CE2 1 
ATOM 3048 C CZ  . PHE A 1 408 ? 186.111 201.965 154.935 1.00 28.07 ? 392 PHE A CZ  1 
ATOM 3049 N N   . PHE A 1 409 ? 187.982 196.436 156.805 1.00 29.16 ? 393 PHE A N   1 
ATOM 3050 C CA  . PHE A 1 409 ? 188.593 195.931 155.583 1.00 29.16 ? 393 PHE A CA  1 
ATOM 3051 C C   . PHE A 1 409 ? 187.894 194.652 155.153 1.00 29.16 ? 393 PHE A C   1 
ATOM 3052 O O   . PHE A 1 409 ? 187.749 193.721 155.951 1.00 29.16 ? 393 PHE A O   1 
ATOM 3053 C CB  . PHE A 1 409 ? 190.091 195.670 155.780 1.00 29.16 ? 393 PHE A CB  1 
ATOM 3054 C CG  . PHE A 1 409 ? 190.938 196.909 155.704 1.00 29.16 ? 393 PHE A CG  1 
ATOM 3055 C CD1 . PHE A 1 409 ? 190.573 197.966 154.888 1.00 29.16 ? 393 PHE A CD1 1 
ATOM 3056 C CD2 . PHE A 1 409 ? 192.102 197.013 156.447 1.00 29.16 ? 393 PHE A CD2 1 
ATOM 3057 C CE1 . PHE A 1 409 ? 191.352 199.106 154.816 1.00 29.16 ? 393 PHE A CE1 1 
ATOM 3058 C CE2 . PHE A 1 409 ? 192.885 198.149 156.380 1.00 29.16 ? 393 PHE A CE2 1 
ATOM 3059 C CZ  . PHE A 1 409 ? 192.509 199.197 155.563 1.00 29.16 ? 393 PHE A CZ  1 
ATOM 3060 N N   . THR A 1 410 ? 187.476 194.607 153.890 1.00 22.09 ? 394 THR A N   1 
ATOM 3061 C CA  . THR A 1 410 ? 186.780 193.444 153.352 1.00 22.09 ? 394 THR A CA  1 
ATOM 3062 C C   . THR A 1 410 ? 187.762 192.290 153.194 1.00 22.09 ? 394 THR A C   1 
ATOM 3063 O O   . THR A 1 410 ? 188.607 192.300 152.293 1.00 22.09 ? 394 THR A O   1 
ATOM 3064 C CB  . THR A 1 410 ? 186.129 193.789 152.016 1.00 22.09 ? 394 THR A CB  1 
ATOM 3065 O OG1 . THR A 1 410 ? 187.127 194.274 151.109 1.00 22.09 ? 394 THR A OG1 1 
ATOM 3066 C CG2 . THR A 1 410 ? 185.063 194.857 152.206 1.00 22.09 ? 394 THR A CG2 1 
ATOM 3067 N N   . LYS A 1 411 ? 187.654 191.295 154.070 1.00 18.68 ? 395 LYS A N   1 
ATOM 3068 C CA  . LYS A 1 411 ? 188.471 190.096 154.003 1.00 18.68 ? 395 LYS A CA  1 
ATOM 3069 C C   . LYS A 1 411 ? 187.680 188.977 153.349 1.00 18.68 ? 395 LYS A C   1 
ATOM 3070 O O   . LYS A 1 411 ? 186.528 188.740 153.737 1.00 18.68 ? 395 LYS A O   1 
ATOM 3071 C CB  . LYS A 1 411 ? 188.922 189.667 155.404 1.00 18.68 ? 395 LYS A CB  1 
ATOM 3072 C CG  . LYS A 1 411 ? 190.046 188.642 155.418 1.00 18.68 ? 395 LYS A CG  1 
ATOM 3073 C CD  . LYS A 1 411 ? 191.352 189.240 154.915 1.00 18.68 ? 395 LYS A CD  1 
ATOM 3074 C CE  . LYS A 1 411 ? 192.447 188.187 154.834 1.00 18.68 ? 395 LYS A CE  1 
ATOM 3075 N NZ  . LYS A 1 411 ? 193.700 188.730 154.241 1.00 18.68 ? 395 LYS A NZ  1 
ATOM 3076 N N   . PRO A 1 412 ? 188.242 188.283 152.353 1.00 14.75 ? 396 PRO A N   1 
ATOM 3077 C CA  . PRO A 1 412 ? 187.508 187.181 151.716 1.00 14.75 ? 396 PRO A CA  1 
ATOM 3078 C C   . PRO A 1 412 ? 187.102 186.109 152.713 1.00 14.75 ? 396 PRO A C   1 
ATOM 3079 O O   . PRO A 1 412 ? 187.955 185.442 153.307 1.00 14.75 ? 396 PRO A O   1 
ATOM 3080 C CB  . PRO A 1 412 ? 188.507 186.645 150.681 1.00 14.75 ? 396 PRO A CB  1 
ATOM 3081 C CG  . PRO A 1 412 ? 189.845 187.128 151.153 1.00 14.75 ? 396 PRO A CG  1 
ATOM 3082 C CD  . PRO A 1 412 ? 189.575 188.468 151.758 1.00 14.75 ? 396 PRO A CD  1 
ATOM 3083 N N   . SER A 1 413 ? 185.799 185.942 152.903 1.00 12.05 ? 397 SER A N   1 
ATOM 3084 C CA  . SER A 1 413 ? 185.269 185.030 153.903 1.00 12.05 ? 397 SER A CA  1 
ATOM 3085 C C   . SER A 1 413 ? 184.779 183.739 153.259 1.00 12.05 ? 397 SER A C   1 
ATOM 3086 O O   . SER A 1 413 ? 184.577 183.654 152.046 1.00 12.05 ? 397 SER A O   1 
ATOM 3087 C CB  . SER A 1 413 ? 184.131 185.690 154.681 1.00 12.05 ? 397 SER A CB  1 
ATOM 3088 O OG  . SER A 1 413 ? 183.184 184.728 155.112 1.00 12.05 ? 397 SER A OG  1 
ATOM 3089 N N   . ARG A 1 414 ? 184.585 182.725 154.101 1.00 7.81  ? 398 ARG A N   1 
ATOM 3090 C CA  . ARG A 1 414 ? 184.090 181.414 153.683 1.00 7.81  ? 398 ARG A CA  1 
ATOM 3091 C C   . ARG A 1 414 ? 182.958 181.014 154.630 1.00 7.81  ? 398 ARG A C   1 
ATOM 3092 O O   . ARG A 1 414 ? 183.171 180.334 155.638 1.00 7.81  ? 398 ARG A O   1 
ATOM 3093 C CB  . ARG A 1 414 ? 185.232 180.393 153.652 1.00 7.81  ? 398 ARG A CB  1 
ATOM 3094 C CG  . ARG A 1 414 ? 186.063 180.317 154.930 1.00 7.81  ? 398 ARG A CG  1 
ATOM 3095 C CD  . ARG A 1 414 ? 187.253 179.386 154.772 1.00 7.81  ? 398 ARG A CD  1 
ATOM 3096 N NE  . ARG A 1 414 ? 188.335 179.997 154.009 1.00 7.81  ? 398 ARG A NE  1 
ATOM 3097 C CZ  . ARG A 1 414 ? 189.623 179.822 154.269 1.00 7.81  ? 398 ARG A CZ  1 
ATOM 3098 N NH1 . ARG A 1 414 ? 190.028 179.054 155.267 1.00 7.81  ? 398 ARG A NH1 1 
ATOM 3099 N NH2 . ARG A 1 414 ? 190.527 180.432 153.508 1.00 7.81  ? 398 ARG A NH2 1 
ATOM 3100 N N   . LEU A 1 415 ? 181.742 181.439 154.300 1.00 8.56  ? 399 LEU A N   1 
ATOM 3101 C CA  . LEU A 1 415 ? 180.568 181.172 155.118 1.00 8.56  ? 399 LEU A CA  1 
ATOM 3102 C C   . LEU A 1 415 ? 179.470 180.573 154.254 1.00 8.56  ? 399 LEU A C   1 
ATOM 3103 O O   . LEU A 1 415 ? 179.245 181.019 153.124 1.00 8.56  ? 399 LEU A O   1 
ATOM 3104 C CB  . LEU A 1 415 ? 180.060 182.447 155.799 1.00 8.56  ? 399 LEU A CB  1 
ATOM 3105 C CG  . LEU A 1 415 ? 180.861 182.931 157.008 1.00 8.56  ? 399 LEU A CG  1 
ATOM 3106 C CD1 . LEU A 1 415 ? 180.258 184.207 157.573 1.00 8.56  ? 399 LEU A CD1 1 
ATOM 3107 C CD2 . LEU A 1 415 ? 180.928 181.849 158.074 1.00 8.56  ? 399 LEU A CD2 1 
ATOM 3108 N N   . ILE A 1 416 ? 178.789 179.567 154.790 1.00 6.70  ? 400 ILE A N   1 
ATOM 3109 C CA  . ILE A 1 416 ? 177.734 178.856 154.081 1.00 6.70  ? 400 ILE A CA  1 
ATOM 3110 C C   . ILE A 1 416 ? 176.425 179.156 154.800 1.00 6.70  ? 400 ILE A C   1 
ATOM 3111 O O   . ILE A 1 416 ? 176.078 178.494 155.785 1.00 6.70  ? 400 ILE A O   1 
ATOM 3112 C CB  . ILE A 1 416 ? 178.006 177.350 154.014 1.00 6.70  ? 400 ILE A CB  1 
ATOM 3113 C CG1 . ILE A 1 416 ? 179.384 177.089 153.406 1.00 6.70  ? 400 ILE A CG1 1 
ATOM 3114 C CG2 . ILE A 1 416 ? 176.929 176.648 153.208 1.00 6.70  ? 400 ILE A CG2 1 
ATOM 3115 C CD1 . ILE A 1 416 ? 179.877 175.679 153.605 1.00 6.70  ? 400 ILE A CD1 1 
ATOM 3116 N N   . GLN A 1 417 ? 175.694 180.153 154.313 1.00 5.76  ? 401 GLN A N   1 
ATOM 3117 C CA  . GLN A 1 417 ? 174.400 180.504 154.876 1.00 5.76  ? 401 GLN A CA  1 
ATOM 3118 C C   . GLN A 1 417 ? 173.293 179.732 154.170 1.00 5.76  ? 401 GLN A C   1 
ATOM 3119 O O   . GLN A 1 417 ? 173.381 179.434 152.976 1.00 5.76  ? 401 GLN A O   1 
ATOM 3120 C CB  . GLN A 1 417 ? 174.150 182.008 154.768 1.00 5.76  ? 401 GLN A CB  1 
ATOM 3121 C CG  . GLN A 1 417 ? 175.207 182.852 155.456 1.00 5.76  ? 401 GLN A CG  1 
ATOM 3122 C CD  . GLN A 1 417 ? 175.095 184.323 155.119 1.00 5.76  ? 401 GLN A CD  1 
ATOM 3123 O OE1 . GLN A 1 417 ? 174.111 184.762 154.524 1.00 5.76  ? 401 GLN A OE1 1 
ATOM 3124 N NE2 . GLN A 1 417 ? 176.106 185.095 155.497 1.00 5.76  ? 401 GLN A NE2 1 
ATOM 3125 N N   . CYS A 1 418 ? 172.243 179.414 154.921 1.00 5.00  ? 402 CYS A N   1 
ATOM 3126 C CA  . CYS A 1 418 ? 171.181 178.519 154.471 1.00 5.00  ? 402 CYS A CA  1 
ATOM 3127 C C   . CYS A 1 418 ? 169.819 179.179 154.620 1.00 5.00  ? 402 CYS A C   1 
ATOM 3128 O O   . CYS A 1 418 ? 168.890 178.615 155.202 1.00 5.00  ? 402 CYS A O   1 
ATOM 3129 C CB  . CYS A 1 418 ? 171.225 177.201 155.235 1.00 5.00  ? 402 CYS A CB  1 
ATOM 3130 S SG  . CYS A 1 418 ? 172.817 176.360 155.162 1.00 5.00  ? 402 CYS A SG  1 
ATOM 3131 N N   . PHE A 1 419 ? 169.691 180.402 154.110 1.00 3.65  ? 403 PHE A N   1 
ATOM 3132 C CA  . PHE A 1 419 ? 168.414 181.104 154.156 1.00 3.65  ? 403 PHE A CA  1 
ATOM 3133 C C   . PHE A 1 419 ? 167.330 180.284 153.465 1.00 3.65  ? 403 PHE A C   1 
ATOM 3134 O O   . PHE A 1 419 ? 167.503 179.834 152.330 1.00 3.65  ? 403 PHE A O   1 
ATOM 3135 C CB  . PHE A 1 419 ? 168.550 182.476 153.497 1.00 3.65  ? 403 PHE A CB  1 
ATOM 3136 C CG  . PHE A 1 419 ? 167.269 183.255 153.446 1.00 3.65  ? 403 PHE A CG  1 
ATOM 3137 C CD1 . PHE A 1 419 ? 166.796 183.908 154.569 1.00 3.65  ? 403 PHE A CD1 1 
ATOM 3138 C CD2 . PHE A 1 419 ? 166.543 183.343 152.272 1.00 3.65  ? 403 PHE A CD2 1 
ATOM 3139 C CE1 . PHE A 1 419 ? 165.619 184.628 154.524 1.00 3.65  ? 403 PHE A CE1 1 
ATOM 3140 C CE2 . PHE A 1 419 ? 165.366 184.061 152.222 1.00 3.65  ? 403 PHE A CE2 1 
ATOM 3141 C CZ  . PHE A 1 419 ? 164.904 184.703 153.348 1.00 3.65  ? 403 PHE A CZ  1 
ATOM 3142 N N   . ASP A 1 420 ? 166.208 180.093 154.156 1.00 4.32  ? 404 ASP A N   1 
ATOM 3143 C CA  . ASP A 1 420 ? 165.132 179.242 153.675 1.00 4.32  ? 404 ASP A CA  1 
ATOM 3144 C C   . ASP A 1 420 ? 164.115 180.053 152.876 1.00 4.32  ? 404 ASP A C   1 
ATOM 3145 O O   . ASP A 1 420 ? 164.210 181.275 152.752 1.00 4.32  ? 404 ASP A O   1 
ATOM 3146 C CB  . ASP A 1 420 ? 164.452 178.530 154.843 1.00 4.32  ? 404 ASP A CB  1 
ATOM 3147 C CG  . ASP A 1 420 ? 165.315 177.445 155.447 1.00 4.32  ? 404 ASP A CG  1 
ATOM 3148 O OD1 . ASP A 1 420 ? 166.463 177.276 154.990 1.00 4.32  ? 404 ASP A OD1 1 
ATOM 3149 O OD2 . ASP A 1 420 ? 164.847 176.762 156.381 1.00 4.32  ? 404 ASP A OD2 1 
ATOM 3150 N N   . THR A 1 421 ? 163.119 179.357 152.326 1.00 5.31  ? 405 THR A N   1 
ATOM 3151 C CA  . THR A 1 421 ? 162.037 179.996 151.593 1.00 5.31  ? 405 THR A CA  1 
ATOM 3152 C C   . THR A 1 421 ? 160.656 179.714 152.162 1.00 5.31  ? 405 THR A C   1 
ATOM 3153 O O   . THR A 1 421 ? 159.707 180.418 151.800 1.00 5.31  ? 405 THR A O   1 
ATOM 3154 C CB  . THR A 1 421 ? 162.052 179.565 150.117 1.00 5.31  ? 405 THR A CB  1 
ATOM 3155 O OG1 . THR A 1 421 ? 161.918 178.141 150.031 1.00 5.31  ? 405 THR A OG1 1 
ATOM 3156 C CG2 . THR A 1 421 ? 163.349 179.989 149.451 1.00 5.31  ? 405 THR A CG2 1 
ATOM 3157 N N   . GLU A 1 422 ? 160.510 178.713 153.031 1.00 8.17  ? 406 GLU A N   1 
ATOM 3158 C CA  . GLU A 1 422 ? 159.228 178.419 153.659 1.00 8.17  ? 406 GLU A CA  1 
ATOM 3159 C C   . GLU A 1 422 ? 159.093 179.113 155.011 1.00 8.17  ? 406 GLU A C   1 
ATOM 3160 O O   . GLU A 1 422 ? 158.163 179.898 155.220 1.00 8.17  ? 406 GLU A O   1 
ATOM 3161 C CB  . GLU A 1 422 ? 159.057 176.906 153.816 1.00 8.17  ? 406 GLU A CB  1 
ATOM 3162 C CG  . GLU A 1 422 ? 159.376 176.119 152.557 1.00 8.17  ? 406 GLU A CG  1 
ATOM 3163 C CD  . GLU A 1 422 ? 159.065 174.644 152.697 1.00 8.17  ? 406 GLU A CD  1 
ATOM 3164 O OE1 . GLU A 1 422 ? 158.337 174.276 153.643 1.00 8.17  ? 406 GLU A OE1 1 
ATOM 3165 O OE2 . GLU A 1 422 ? 159.549 173.852 151.861 1.00 8.17  ? 406 GLU A OE2 1 
ATOM 3166 N N   . THR A 1 423 ? 160.010 178.832 155.932 1.00 9.82  ? 407 THR A N   1 
ATOM 3167 C CA  . THR A 1 423 ? 160.106 179.532 157.211 1.00 9.82  ? 407 THR A CA  1 
ATOM 3168 C C   . THR A 1 423 ? 161.384 180.360 157.154 1.00 9.82  ? 407 THR A C   1 
ATOM 3169 O O   . THR A 1 423 ? 162.472 179.854 157.448 1.00 9.82  ? 407 THR A O   1 
ATOM 3170 C CB  . THR A 1 423 ? 160.118 178.556 158.384 1.00 9.82  ? 407 THR A CB  1 
ATOM 3171 O OG1 . THR A 1 423 ? 161.403 177.928 158.471 1.00 9.82  ? 407 THR A OG1 1 
ATOM 3172 C CG2 . THR A 1 423 ? 159.050 177.489 158.199 1.00 9.82  ? 407 THR A CG2 1 
ATOM 3173 N N   . ASP A 1 424 ? 161.249 181.629 156.778 1.00 6.65  ? 408 ASP A N   1 
ATOM 3174 C CA  . ASP A 1 424 ? 162.399 182.465 156.452 1.00 6.65  ? 408 ASP A CA  1 
ATOM 3175 C C   . ASP A 1 424 ? 163.264 182.671 157.688 1.00 6.65  ? 408 ASP A C   1 
ATOM 3176 O O   . ASP A 1 424 ? 162.882 183.392 158.615 1.00 6.65  ? 408 ASP A O   1 
ATOM 3177 C CB  . ASP A 1 424 ? 161.925 183.795 155.878 1.00 6.65  ? 408 ASP A CB  1 
ATOM 3178 C CG  . ASP A 1 424 ? 160.763 183.628 154.919 1.00 6.65  ? 408 ASP A CG  1 
ATOM 3179 O OD1 . ASP A 1 424 ? 160.908 183.989 153.733 1.00 6.65  ? 408 ASP A OD1 1 
ATOM 3180 O OD2 . ASP A 1 424 ? 159.702 183.133 155.353 1.00 6.65  ? 408 ASP A OD2 1 
ATOM 3181 N N   . LYS A 1 425 ? 164.433 182.035 157.698 1.00 8.01  ? 409 LYS A N   1 
ATOM 3182 C CA  . LYS A 1 425 ? 165.358 182.105 158.818 1.00 8.01  ? 409 LYS A CA  1 
ATOM 3183 C C   . LYS A 1 425 ? 166.739 181.712 158.315 1.00 8.01  ? 409 LYS A C   1 
ATOM 3184 O O   . LYS A 1 425 ? 166.866 180.931 157.370 1.00 8.01  ? 409 LYS A O   1 
ATOM 3185 C CB  . LYS A 1 425 ? 164.911 181.190 159.966 1.00 8.01  ? 409 LYS A CB  1 
ATOM 3186 C CG  . LYS A 1 425 ? 165.734 181.313 161.240 1.00 8.01  ? 409 LYS A CG  1 
ATOM 3187 C CD  . LYS A 1 425 ? 165.558 182.680 161.883 1.00 8.01  ? 409 LYS A CD  1 
ATOM 3188 C CE  . LYS A 1 425 ? 166.384 182.804 163.152 1.00 8.01  ? 409 LYS A CE  1 
ATOM 3189 N NZ  . LYS A 1 425 ? 167.788 182.353 162.950 1.00 8.01  ? 409 LYS A NZ  1 
ATOM 3190 N N   . CYS A 1 426 ? 167.768 182.268 158.948 1.00 9.82  ? 410 CYS A N   1 
ATOM 3191 C CA  . CYS A 1 426 ? 169.152 182.005 158.577 1.00 9.82  ? 410 CYS A CA  1 
ATOM 3192 C C   . CYS A 1 426 ? 169.725 180.921 159.482 1.00 9.82  ? 410 CYS A C   1 
ATOM 3193 O O   . CYS A 1 426 ? 169.531 180.958 160.701 1.00 9.82  ? 410 CYS A O   1 
ATOM 3194 C CB  . CYS A 1 426 ? 169.989 183.280 158.667 1.00 9.82  ? 410 CYS A CB  1 
ATOM 3195 S SG  . CYS A 1 426 ? 171.762 183.006 158.531 1.00 9.82  ? 410 CYS A SG  1 
ATOM 3196 N N   . HIS A 1 427 ? 170.428 179.963 158.883 1.00 11.90 ? 411 HIS A N   1 
ATOM 3197 C CA  . HIS A 1 427 ? 170.898 178.754 159.558 1.00 11.90 ? 411 HIS A CA  1 
ATOM 3198 C C   . HIS A 1 427 ? 172.362 178.485 159.229 1.00 11.90 ? 411 HIS A C   1 
ATOM 3199 O O   . HIS A 1 427 ? 172.721 177.403 158.760 1.00 11.90 ? 411 HIS A O   1 
ATOM 3200 C CB  . HIS A 1 427 ? 170.044 177.546 159.185 1.00 11.90 ? 411 HIS A CB  1 
ATOM 3201 C CG  . HIS A 1 427 ? 168.584 177.727 159.460 1.00 11.90 ? 411 HIS A CG  1 
ATOM 3202 N ND1 . HIS A 1 427 ? 167.961 177.180 160.561 1.00 11.90 ? 411 HIS A ND1 1 
ATOM 3203 C CD2 . HIS A 1 427 ? 167.622 178.385 158.772 1.00 11.90 ? 411 HIS A CD2 1 
ATOM 3204 C CE1 . HIS A 1 427 ? 166.679 177.499 160.543 1.00 11.90 ? 411 HIS A CE1 1 
ATOM 3205 N NE2 . HIS A 1 427 ? 166.447 178.230 159.467 1.00 11.90 ? 411 HIS A NE2 1 
ATOM 3206 N N   . VAL A 1 428 ? 173.217 179.494 159.438 1.00 8.29  ? 412 VAL A N   1 
ATOM 3207 C CA  . VAL A 1 428 ? 174.638 179.385 159.110 1.00 8.29  ? 412 VAL A CA  1 
ATOM 3208 C C   . VAL A 1 428 ? 175.206 178.075 159.632 1.00 8.29  ? 412 VAL A C   1 
ATOM 3209 O O   . VAL A 1 428 ? 175.096 177.760 160.821 1.00 8.29  ? 412 VAL A O   1 
ATOM 3210 C CB  . VAL A 1 428 ? 175.410 180.588 159.682 1.00 8.29  ? 412 VAL A CB  1 
ATOM 3211 C CG1 . VAL A 1 428 ? 176.907 180.345 159.594 1.00 8.29  ? 412 VAL A CG1 1 
ATOM 3212 C CG2 . VAL A 1 428 ? 175.040 181.855 158.944 1.00 8.29  ? 412 VAL A CG2 1 
ATOM 3213 N N   . LYS A 1 429 ? 175.816 177.302 158.730 1.00 8.00  ? 413 LYS A N   1 
ATOM 3214 C CA  . LYS A 1 429 ? 176.374 176.000 159.055 1.00 8.00  ? 413 LYS A CA  1 
ATOM 3215 C C   . LYS A 1 429 ? 177.619 176.145 159.929 1.00 8.00  ? 413 LYS A C   1 
ATOM 3216 O O   . LYS A 1 429 ? 178.382 177.104 159.783 1.00 8.00  ? 413 LYS A O   1 
ATOM 3217 C CB  . LYS A 1 429 ? 176.733 175.244 157.780 1.00 8.00  ? 413 LYS A CB  1 
ATOM 3218 C CG  . LYS A 1 429 ? 175.543 174.866 156.917 1.00 8.00  ? 413 LYS A CG  1 
ATOM 3219 C CD  . LYS A 1 429 ? 174.981 173.514 157.315 1.00 8.00  ? 413 LYS A CD  1 
ATOM 3220 C CE  . LYS A 1 429 ? 173.804 173.129 156.438 1.00 8.00  ? 413 LYS A CE  1 
ATOM 3221 N NZ  . LYS A 1 429 ? 172.657 174.060 156.614 1.00 8.00  ? 413 LYS A NZ  1 
ATOM 3222 N N   . PRO A 1 430 ? 177.848 175.196 160.850 1.00 8.78  ? 414 PRO A N   1 
ATOM 3223 C CA  . PRO A 1 430 ? 179.031 175.234 161.717 1.00 8.78  ? 414 PRO A CA  1 
ATOM 3224 C C   . PRO A 1 430 ? 180.281 174.641 161.068 1.00 8.78  ? 414 PRO A C   1 
ATOM 3225 O O   . PRO A 1 430 ? 181.013 173.856 161.679 1.00 8.78  ? 414 PRO A O   1 
ATOM 3226 C CB  . PRO A 1 430 ? 178.582 174.412 162.930 1.00 8.78  ? 414 PRO A CB  1 
ATOM 3227 C CG  . PRO A 1 430 ? 177.656 173.406 162.343 1.00 8.78  ? 414 PRO A CG  1 
ATOM 3228 C CD  . PRO A 1 430 ? 176.912 174.129 161.247 1.00 8.78  ? 414 PRO A CD  1 
ATOM 3229 N N   . TYR A 1 431 ? 180.537 175.019 159.817 1.00 6.39  ? 415 TYR A N   1 
ATOM 3230 C CA  . TYR A 1 431 ? 181.766 174.631 159.136 1.00 6.39  ? 415 TYR A CA  1 
ATOM 3231 C C   . TYR A 1 431 ? 182.006 175.593 157.983 1.00 6.39  ? 415 TYR A C   1 
ATOM 3232 O O   . TYR A 1 431 ? 181.102 176.313 157.552 1.00 6.39  ? 415 TYR A O   1 
ATOM 3233 C CB  . TYR A 1 431 ? 181.720 173.177 158.647 1.00 6.39  ? 415 TYR A CB  1 
ATOM 3234 C CG  . TYR A 1 431 ? 180.551 172.834 157.753 1.00 6.39  ? 415 TYR A CG  1 
ATOM 3235 C CD1 . TYR A 1 431 ? 179.367 172.345 158.286 1.00 6.39  ? 415 TYR A CD1 1 
ATOM 3236 C CD2 . TYR A 1 431 ? 180.639 172.975 156.375 1.00 6.39  ? 415 TYR A CD2 1 
ATOM 3237 C CE1 . TYR A 1 431 ? 178.298 172.020 157.474 1.00 6.39  ? 415 TYR A CE1 1 
ATOM 3238 C CE2 . TYR A 1 431 ? 179.575 172.653 155.555 1.00 6.39  ? 415 TYR A CE2 1 
ATOM 3239 C CZ  . TYR A 1 431 ? 178.407 172.177 156.110 1.00 6.39  ? 415 TYR A CZ  1 
ATOM 3240 O OH  . TYR A 1 431 ? 177.345 171.855 155.299 1.00 6.39  ? 415 TYR A OH  1 
ATOM 3241 N N   . VAL A 1 432 ? 183.241 175.595 157.491 1.00 5.88  ? 416 VAL A N   1 
ATOM 3242 C CA  . VAL A 1 432 ? 183.674 176.550 156.483 1.00 5.88  ? 416 VAL A CA  1 
ATOM 3243 C C   . VAL A 1 432 ? 184.083 175.809 155.217 1.00 5.88  ? 416 VAL A C   1 
ATOM 3244 O O   . VAL A 1 432 ? 184.366 174.607 155.223 1.00 5.88  ? 416 VAL A O   1 
ATOM 3245 C CB  . VAL A 1 432 ? 184.829 177.437 156.994 1.00 5.88  ? 416 VAL A CB  1 
ATOM 3246 C CG1 . VAL A 1 432 ? 184.554 177.899 158.415 1.00 5.88  ? 416 VAL A CG1 1 
ATOM 3247 C CG2 . VAL A 1 432 ? 186.146 176.681 156.925 1.00 5.88  ? 416 VAL A CG2 1 
ATOM 3248 N N   . LEU A 1 433 ? 184.105 176.551 154.112 1.00 4.51  ? 417 LEU A N   1 
ATOM 3249 C CA  . LEU A 1 433 ? 184.492 175.986 152.831 1.00 4.51  ? 417 LEU A CA  1 
ATOM 3250 C C   . LEU A 1 433 ? 186.005 175.777 152.775 1.00 4.51  ? 417 LEU A C   1 
ATOM 3251 O O   . LEU A 1 433 ? 186.755 176.412 153.520 1.00 4.51  ? 417 LEU A O   1 
ATOM 3252 C CB  . LEU A 1 433 ? 184.054 176.904 151.693 1.00 4.51  ? 417 LEU A CB  1 
ATOM 3253 C CG  . LEU A 1 433 ? 182.551 177.026 151.450 1.00 4.51  ? 417 LEU A CG  1 
ATOM 3254 C CD1 . LEU A 1 433 ? 182.211 178.412 150.938 1.00 4.51  ? 417 LEU A CD1 1 
ATOM 3255 C CD2 . LEU A 1 433 ? 182.085 175.970 150.472 1.00 4.51  ? 417 LEU A CD2 1 
ATOM 3256 N N   . PRO A 1 434 ? 186.477 174.878 151.908 1.00 4.41  ? 418 PRO A N   1 
ATOM 3257 C CA  . PRO A 1 434 ? 187.932 174.712 151.754 1.00 4.41  ? 418 PRO A CA  1 
ATOM 3258 C C   . PRO A 1 434 ? 188.645 175.973 151.297 1.00 4.41  ? 418 PRO A C   1 
ATOM 3259 O O   . PRO A 1 434 ? 189.816 176.169 151.647 1.00 4.41  ? 418 PRO A O   1 
ATOM 3260 C CB  . PRO A 1 434 ? 188.051 173.588 150.715 1.00 4.41  ? 418 PRO A CB  1 
ATOM 3261 C CG  . PRO A 1 434 ? 186.761 172.856 150.785 1.00 4.41  ? 418 PRO A CG  1 
ATOM 3262 C CD  . PRO A 1 434 ? 185.716 173.857 151.168 1.00 4.41  ? 418 PRO A CD  1 
ATOM 3263 N N   . PHE A 1 435 ? 187.986 176.832 150.523 1.00 3.90  ? 419 PHE A N   1 
ATOM 3264 C CA  . PHE A 1 435 ? 188.587 178.068 150.039 1.00 3.90  ? 419 PHE A CA  1 
ATOM 3265 C C   . PHE A 1 435 ? 187.629 179.230 150.274 1.00 3.90  ? 419 PHE A C   1 
ATOM 3266 O O   . PHE A 1 435 ? 186.594 179.093 150.934 1.00 3.90  ? 419 PHE A O   1 
ATOM 3267 C CB  . PHE A 1 435 ? 188.962 177.963 148.554 1.00 3.90  ? 419 PHE A CB  1 
ATOM 3268 C CG  . PHE A 1 435 ? 187.925 177.278 147.708 1.00 3.90  ? 419 PHE A CG  1 
ATOM 3269 C CD1 . PHE A 1 435 ? 186.654 177.810 147.571 1.00 3.90  ? 419 PHE A CD1 1 
ATOM 3270 C CD2 . PHE A 1 435 ? 188.231 176.112 147.034 1.00 3.90  ? 419 PHE A CD2 1 
ATOM 3271 C CE1 . PHE A 1 435 ? 185.705 177.182 146.791 1.00 3.90  ? 419 PHE A CE1 1 
ATOM 3272 C CE2 . PHE A 1 435 ? 187.288 175.484 146.250 1.00 3.90  ? 419 PHE A CE2 1 
ATOM 3273 C CZ  . PHE A 1 435 ? 186.023 176.017 146.129 1.00 3.90  ? 419 PHE A CZ  1 
ATOM 3274 N N   . ALA A 1 436 ? 187.985 180.387 149.721 1.00 4.43  ? 420 ALA A N   1 
ATOM 3275 C CA  . ALA A 1 436 ? 187.166 181.586 149.830 1.00 4.43  ? 420 ALA A CA  1 
ATOM 3276 C C   . ALA A 1 436 ? 187.503 182.510 148.670 1.00 4.43  ? 420 ALA A C   1 
ATOM 3277 O O   . ALA A 1 436 ? 188.539 182.361 148.017 1.00 4.43  ? 420 ALA A O   1 
ATOM 3278 C CB  . ALA A 1 436 ? 187.381 182.295 151.170 1.00 4.43  ? 420 ALA A CB  1 
ATOM 3279 N N   . GLY A 1 437 ? 186.614 183.469 148.423 1.00 4.56  ? 421 GLY A N   1 
ATOM 3280 C CA  . GLY A 1 437 ? 186.818 184.406 147.336 1.00 4.56  ? 421 GLY A CA  1 
ATOM 3281 C C   . GLY A 1 437 ? 185.549 184.809 146.613 1.00 4.56  ? 421 GLY A C   1 
ATOM 3282 O O   . GLY A 1 437 ? 184.598 185.299 147.231 1.00 4.56  ? 421 GLY A O   1 
ATOM 3283 N N   . ARG A 1 438 ? 185.526 184.604 145.297 1.00 4.09  ? 422 ARG A N   1 
ATOM 3284 C CA  . ARG A 1 438 ? 184.398 184.999 144.464 1.00 4.09  ? 422 ARG A CA  1 
ATOM 3285 C C   . ARG A 1 438 ? 183.911 183.759 143.722 1.00 4.09  ? 422 ARG A C   1 
ATOM 3286 O O   . ARG A 1 438 ? 183.825 183.744 142.491 1.00 4.09  ? 422 ARG A O   1 
ATOM 3287 C CB  . ARG A 1 438 ? 184.804 186.132 143.511 1.00 4.09  ? 422 ARG A CB  1 
ATOM 3288 C CG  . ARG A 1 438 ? 183.663 187.037 143.008 1.00 4.09  ? 422 ARG A CG  1 
ATOM 3289 C CD  . ARG A 1 438 ? 182.841 186.439 141.875 1.00 4.09  ? 422 ARG A CD  1 
ATOM 3290 N NE  . ARG A 1 438 ? 181.647 187.221 141.578 1.00 4.09  ? 422 ARG A NE  1 
ATOM 3291 C CZ  . ARG A 1 438 ? 180.468 187.036 142.158 1.00 4.09  ? 422 ARG A CZ  1 
ATOM 3292 N NH1 . ARG A 1 438 ? 180.288 186.100 143.075 1.00 4.09  ? 422 ARG A NH1 1 
ATOM 3293 N NH2 . ARG A 1 438 ? 179.444 187.808 141.806 1.00 4.09  ? 422 ARG A NH2 1 
ATOM 3294 N N   . MET A 1 439 ? 183.653 182.690 144.469 1.00 0.88  ? 423 MET A N   1 
ATOM 3295 C CA  . MET A 1 439 ? 183.254 181.426 143.875 1.00 0.88  ? 423 MET A CA  1 
ATOM 3296 C C   . MET A 1 439 ? 181.905 181.548 143.169 1.00 0.88  ? 423 MET A C   1 
ATOM 3297 O O   . MET A 1 439 ? 181.049 182.358 143.534 1.00 0.88  ? 423 MET A O   1 
ATOM 3298 C CB  . MET A 1 439 ? 183.190 180.335 144.943 1.00 0.88  ? 423 MET A CB  1 
ATOM 3299 C CG  . MET A 1 439 ? 182.140 180.574 146.007 1.00 0.88  ? 423 MET A CG  1 
ATOM 3300 S SD  . MET A 1 439 ? 182.534 179.745 147.554 1.00 0.88  ? 423 MET A SD  1 
ATOM 3301 C CE  . MET A 1 439 ? 184.175 180.383 147.862 1.00 0.88  ? 423 MET A CE  1 
ATOM 3302 N N   . HIS A 1 440 ? 181.731 180.729 142.133 1.00 0.43  ? 424 HIS A N   1 
ATOM 3303 C CA  . HIS A 1 440 ? 180.491 180.658 141.371 1.00 0.43  ? 424 HIS A CA  1 
ATOM 3304 C C   . HIS A 1 440 ? 179.955 179.239 141.465 1.00 0.43  ? 424 HIS A C   1 
ATOM 3305 O O   . HIS A 1 440 ? 180.677 178.282 141.170 1.00 0.43  ? 424 HIS A O   1 
ATOM 3306 C CB  . HIS A 1 440 ? 180.720 181.056 139.908 1.00 0.43  ? 424 HIS A CB  1 
ATOM 3307 C CG  . HIS A 1 440 ? 179.458 181.257 139.125 1.00 0.43  ? 424 HIS A CG  1 
ATOM 3308 N ND1 . HIS A 1 440 ? 178.500 180.276 138.983 1.00 0.43  ? 424 HIS A ND1 1 
ATOM 3309 C CD2 . HIS A 1 440 ? 179.000 182.329 138.437 1.00 0.43  ? 424 HIS A CD2 1 
ATOM 3310 C CE1 . HIS A 1 440 ? 177.507 180.735 138.244 1.00 0.43  ? 424 HIS A CE1 1 
ATOM 3311 N NE2 . HIS A 1 440 ? 177.785 181.979 137.900 1.00 0.43  ? 424 HIS A NE2 1 
ATOM 3312 N N   . ALA A 1 441 ? 178.697 179.103 141.868 1.00 9.84  ? 425 ALA A N   1 
ATOM 3313 C CA  . ALA A 1 441 ? 178.092 177.805 142.118 1.00 9.84  ? 425 ALA A CA  1 
ATOM 3314 C C   . ALA A 1 441 ? 177.173 177.397 140.973 1.00 9.84  ? 425 ALA A C   1 
ATOM 3315 O O   . ALA A 1 441 ? 176.708 178.227 140.188 1.00 9.84  ? 425 ALA A O   1 
ATOM 3316 C CB  . ALA A 1 441 ? 177.309 177.817 143.433 1.00 9.84  ? 425 ALA A CB  1 
ATOM 3317 N N   . ALA A 1 442 ? 176.914 176.094 140.890 1.00 3.28  ? 426 ALA A N   1 
ATOM 3318 C CA  . ALA A 1 442 ? 176.055 175.540 139.846 1.00 3.28  ? 426 ALA A CA  1 
ATOM 3319 C C   . ALA A 1 442 ? 175.448 174.247 140.371 1.00 3.28  ? 426 ALA A C   1 
ATOM 3320 O O   . ALA A 1 442 ? 176.161 173.256 140.547 1.00 3.28  ? 426 ALA A O   1 
ATOM 3321 C CB  . ALA A 1 442 ? 176.838 175.295 138.562 1.00 3.28  ? 426 ALA A CB  1 
ATOM 3322 N N   . VAL A 1 443 ? 174.136 174.258 140.611 1.00 9.84  ? 427 VAL A N   1 
ATOM 3323 C CA  . VAL A 1 443 ? 173.463 173.095 141.176 1.00 9.84  ? 427 VAL A CA  1 
ATOM 3324 C C   . VAL A 1 443 ? 173.425 171.968 140.154 1.00 9.84  ? 427 VAL A C   1 
ATOM 3325 O O   . VAL A 1 443 ? 173.090 172.175 138.980 1.00 9.84  ? 427 VAL A O   1 
ATOM 3326 C CB  . VAL A 1 443 ? 172.046 173.470 141.638 1.00 9.84  ? 427 VAL A CB  1 
ATOM 3327 C CG1 . VAL A 1 443 ? 171.393 172.299 142.346 1.00 9.84  ? 427 VAL A CG1 1 
ATOM 3328 C CG2 . VAL A 1 443 ? 172.095 174.681 142.546 1.00 9.84  ? 427 VAL A CG2 1 
ATOM 3329 N N   . HIS A 1 444 ? 173.771 170.762 140.599 1.00 1.99  ? 428 HIS A N   1 
ATOM 3330 C CA  . HIS A 1 444 ? 173.721 169.567 139.760 1.00 1.99  ? 428 HIS A CA  1 
ATOM 3331 C C   . HIS A 1 444 ? 173.145 168.438 140.602 1.00 1.99  ? 428 HIS A C   1 
ATOM 3332 O O   . HIS A 1 444 ? 173.775 168.008 141.573 1.00 1.99  ? 428 HIS A O   1 
ATOM 3333 C CB  . HIS A 1 444 ? 175.107 169.205 139.227 1.00 1.99  ? 428 HIS A CB  1 
ATOM 3334 C CG  . HIS A 1 444 ? 175.107 168.067 138.255 1.00 1.99  ? 428 HIS A CG  1 
ATOM 3335 N ND1 . HIS A 1 444 ? 173.950 167.456 137.821 1.00 1.99  ? 428 HIS A ND1 1 
ATOM 3336 C CD2 . HIS A 1 444 ? 176.125 167.427 137.633 1.00 1.99  ? 428 HIS A CD2 1 
ATOM 3337 C CE1 . HIS A 1 444 ? 174.255 166.490 136.973 1.00 1.99  ? 428 HIS A CE1 1 
ATOM 3338 N NE2 . HIS A 1 444 ? 175.569 166.451 136.842 1.00 1.99  ? 428 HIS A NE2 1 
ATOM 3339 N N   . LYS A 1 445 ? 171.958 167.957 140.223 1.00 9.84  ? 429 LYS A N   1 
ATOM 3340 C CA  . LYS A 1 445 ? 171.233 166.953 140.994 1.00 9.84  ? 429 LYS A CA  1 
ATOM 3341 C C   . LYS A 1 445 ? 171.093 167.393 142.446 1.00 9.84  ? 429 LYS A C   1 
ATOM 3342 O O   . LYS A 1 445 ? 170.646 168.511 142.720 1.00 9.84  ? 429 LYS A O   1 
ATOM 3343 C CB  . LYS A 1 445 ? 171.930 165.594 140.906 1.00 9.84  ? 429 LYS A CB  1 
ATOM 3344 C CG  . LYS A 1 445 ? 172.111 165.078 139.487 1.00 9.84  ? 429 LYS A CG  1 
ATOM 3345 C CD  . LYS A 1 445 ? 170.773 164.746 138.845 1.00 9.84  ? 429 LYS A CD  1 
ATOM 3346 C CE  . LYS A 1 445 ? 170.931 164.386 137.376 1.00 9.84  ? 429 LYS A CE  1 
ATOM 3347 N NZ  . LYS A 1 445 ? 171.678 163.114 137.182 1.00 9.84  ? 429 LYS A NZ  1 
ATOM 3348 N N   . ASP A 1 446 ? 171.466 166.523 143.383 1.00 9.84  ? 430 ASP A N   1 
ATOM 3349 C CA  . ASP A 1 446 ? 171.439 166.872 144.797 1.00 9.84  ? 430 ASP A CA  1 
ATOM 3350 C C   . ASP A 1 446 ? 172.676 167.645 145.240 1.00 9.84  ? 430 ASP A C   1 
ATOM 3351 O O   . ASP A 1 446 ? 172.644 168.283 146.298 1.00 9.84  ? 430 ASP A O   1 
ATOM 3352 C CB  . ASP A 1 446 ? 171.284 165.599 145.638 1.00 9.84  ? 430 ASP A CB  1 
ATOM 3353 C CG  . ASP A 1 446 ? 171.159 165.886 147.121 1.00 9.84  ? 430 ASP A CG  1 
ATOM 3354 O OD1 . ASP A 1 446 ? 170.468 166.861 147.484 1.00 9.84  ? 430 ASP A OD1 1 
ATOM 3355 O OD2 . ASP A 1 446 ? 171.747 165.134 147.925 1.00 9.84  ? 430 ASP A OD2 1 
ATOM 3356 N N   . LEU A 1 447 ? 173.749 167.625 144.454 1.00 9.84  ? 431 LEU A N   1 
ATOM 3357 C CA  . LEU A 1 447 ? 174.998 168.260 144.839 1.00 9.84  ? 431 LEU A CA  1 
ATOM 3358 C C   . LEU A 1 447 ? 175.028 169.721 144.399 1.00 9.84  ? 431 LEU A C   1 
ATOM 3359 O O   . LEU A 1 447 ? 174.202 170.177 143.604 1.00 9.84  ? 431 LEU A O   1 
ATOM 3360 C CB  . LEU A 1 447 ? 176.181 167.512 144.232 1.00 9.84  ? 431 LEU A CB  1 
ATOM 3361 C CG  . LEU A 1 447 ? 175.990 166.002 144.128 1.00 9.84  ? 431 LEU A CG  1 
ATOM 3362 C CD1 . LEU A 1 447 ? 176.994 165.405 143.169 1.00 9.84  ? 431 LEU A CD1 1 
ATOM 3363 C CD2 . LEU A 1 447 ? 176.113 165.365 145.497 1.00 9.84  ? 431 LEU A CD2 1 
ATOM 3364 N N   . VAL A 1 448 ? 176.001 170.458 144.931 1.00 0.31  ? 432 VAL A N   1 
ATOM 3365 C CA  . VAL A 1 448 ? 176.190 171.875 144.620 1.00 0.31  ? 432 VAL A CA  1 
ATOM 3366 C C   . VAL A 1 448 ? 177.665 172.055 144.271 1.00 0.31  ? 432 VAL A C   1 
ATOM 3367 O O   . VAL A 1 448 ? 178.514 172.203 145.155 1.00 0.31  ? 432 VAL A O   1 
ATOM 3368 C CB  . VAL A 1 448 ? 175.779 172.795 145.774 1.00 0.31  ? 432 VAL A CB  1 
ATOM 3369 C CG1 . VAL A 1 448 ? 175.956 174.248 145.378 1.00 0.31  ? 432 VAL A CG1 1 
ATOM 3370 C CG2 . VAL A 1 448 ? 174.343 172.527 146.186 1.00 0.31  ? 432 VAL A CG2 1 
ATOM 3371 N N   . PHE A 1 449 ? 177.979 172.047 142.979 1.00 9.84  ? 433 PHE A N   1 
ATOM 3372 C CA  . PHE A 1 449 ? 179.355 172.235 142.541 1.00 9.84  ? 433 PHE A CA  1 
ATOM 3373 C C   . PHE A 1 449 ? 179.799 173.675 142.767 1.00 9.84  ? 433 PHE A C   1 
ATOM 3374 O O   . PHE A 1 449 ? 179.010 174.613 142.638 1.00 9.84  ? 433 PHE A O   1 
ATOM 3375 C CB  . PHE A 1 449 ? 179.496 171.867 141.066 1.00 9.84  ? 433 PHE A CB  1 
ATOM 3376 C CG  . PHE A 1 449 ? 179.502 170.390 140.808 1.00 9.84  ? 433 PHE A CG  1 
ATOM 3377 C CD1 . PHE A 1 449 ? 178.318 169.686 140.708 1.00 9.84  ? 433 PHE A CD1 1 
ATOM 3378 C CD2 . PHE A 1 449 ? 180.693 169.706 140.662 1.00 9.84  ? 433 PHE A CD2 1 
ATOM 3379 C CE1 . PHE A 1 449 ? 178.323 168.328 140.469 1.00 9.84  ? 433 PHE A CE1 1 
ATOM 3380 C CE2 . PHE A 1 449 ? 180.704 168.348 140.423 1.00 9.84  ? 433 PHE A CE2 1 
ATOM 3381 C CZ  . PHE A 1 449 ? 179.518 167.659 140.327 1.00 9.84  ? 433 PHE A CZ  1 
ATOM 3382 N N   . ILE A 1 450 ? 181.075 173.846 143.108 1.00 0.42  ? 434 ILE A N   1 
ATOM 3383 C CA  . ILE A 1 450 ? 181.655 175.152 143.400 1.00 0.42  ? 434 ILE A CA  1 
ATOM 3384 C C   . ILE A 1 450 ? 182.976 175.276 142.655 1.00 0.42  ? 434 ILE A C   1 
ATOM 3385 O O   . ILE A 1 450 ? 183.741 174.310 142.570 1.00 0.42  ? 434 ILE A O   1 
ATOM 3386 C CB  . ILE A 1 450 ? 181.869 175.351 144.916 1.00 0.42  ? 434 ILE A CB  1 
ATOM 3387 C CG1 . ILE A 1 450 ? 180.561 175.145 145.678 1.00 0.42  ? 434 ILE A CG1 1 
ATOM 3388 C CG2 . ILE A 1 450 ? 182.430 176.728 145.203 1.00 0.42  ? 434 ILE A CG2 1 
ATOM 3389 C CD1 . ILE A 1 450 ? 180.736 175.102 147.175 1.00 0.42  ? 434 ILE A CD1 1 
ATOM 3390 N N   . VAL A 1 451 ? 183.243 176.461 142.110 1.00 0.30  ? 435 VAL A N   1 
ATOM 3391 C CA  . VAL A 1 451 ? 184.497 176.751 141.425 1.00 0.30  ? 435 VAL A CA  1 
ATOM 3392 C C   . VAL A 1 451 ? 185.111 177.999 142.044 1.00 0.30  ? 435 VAL A C   1 
ATOM 3393 O O   . VAL A 1 451 ? 184.474 179.056 142.075 1.00 0.30  ? 435 VAL A O   1 
ATOM 3394 C CB  . VAL A 1 451 ? 184.295 176.951 139.913 1.00 0.30  ? 435 VAL A CB  1 
ATOM 3395 C CG1 . VAL A 1 451 ? 185.587 177.416 139.275 1.00 0.30  ? 435 VAL A CG1 1 
ATOM 3396 C CG2 . VAL A 1 451 ? 183.810 175.666 139.270 1.00 0.30  ? 435 VAL A CG2 1 
ATOM 3397 N N   . ALA A 1 452 ? 186.348 177.880 142.517 1.00 4.68  ? 436 ALA A N   1 
ATOM 3398 C CA  . ALA A 1 452 ? 187.025 178.961 143.217 1.00 4.68  ? 436 ALA A CA  1 
ATOM 3399 C C   . ALA A 1 452 ? 187.843 179.804 142.240 1.00 4.68  ? 436 ALA A C   1 
ATOM 3400 O O   . ALA A 1 452 ? 187.689 179.714 141.020 1.00 4.68  ? 436 ALA A O   1 
ATOM 3401 C CB  . ALA A 1 452 ? 187.905 178.400 144.330 1.00 4.68  ? 436 ALA A CB  1 
ATOM 3402 N N   . GLU A 1 453 ? 188.726 180.644 142.782 1.00 8.95  ? 437 GLU A N   1 
ATOM 3403 C CA  . GLU A 1 453 ? 189.633 181.468 141.982 1.00 8.95  ? 437 GLU A CA  1 
ATOM 3404 C C   . GLU A 1 453 ? 190.801 180.624 141.463 1.00 8.95  ? 437 GLU A C   1 
ATOM 3405 O O   . GLU A 1 453 ? 191.969 180.853 141.772 1.00 8.95  ? 437 GLU A O   1 
ATOM 3406 C CB  . GLU A 1 453 ? 190.132 182.650 142.802 1.00 8.95  ? 437 GLU A CB  1 
ATOM 3407 C CG  . GLU A 1 453 ? 189.061 183.664 143.167 1.00 8.95  ? 437 GLU A CG  1 
ATOM 3408 C CD  . GLU A 1 453 ? 189.592 184.770 144.061 1.00 8.95  ? 437 GLU A CD  1 
ATOM 3409 O OE1 . GLU A 1 453 ? 190.485 184.491 144.888 1.00 8.95  ? 437 GLU A OE1 1 
ATOM 3410 O OE2 . GLU A 1 453 ? 189.116 185.918 143.935 1.00 8.95  ? 437 GLU A OE2 1 
ATOM 3411 N N   . GLY A 1 454 ? 190.457 179.632 140.657 1.00 7.67  ? 438 GLY A N   1 
ATOM 3412 C CA  . GLY A 1 454 ? 191.440 178.702 140.127 1.00 7.67  ? 438 GLY A CA  1 
ATOM 3413 C C   . GLY A 1 454 ? 190.757 177.425 139.669 1.00 7.67  ? 438 GLY A C   1 
ATOM 3414 O O   . GLY A 1 454 ? 189.605 177.446 139.236 1.00 7.67  ? 438 GLY A O   1 
ATOM 3415 N N   . ASP A 1 455 ? 191.491 176.321 139.778 1.00 10.00 ? 439 ASP A N   1 
ATOM 3416 C CA  . ASP A 1 455 ? 190.982 174.997 139.423 1.00 10.00 ? 439 ASP A CA  1 
ATOM 3417 C C   . ASP A 1 455 ? 190.931 174.165 140.700 1.00 10.00 ? 439 ASP A C   1 
ATOM 3418 O O   . ASP A 1 455 ? 191.857 173.412 141.008 1.00 10.00 ? 439 ASP A O   1 
ATOM 3419 C CB  . ASP A 1 455 ? 191.864 174.352 138.351 1.00 10.00 ? 439 ASP A CB  1 
ATOM 3420 C CG  . ASP A 1 455 ? 191.181 173.197 137.649 1.00 10.00 ? 439 ASP A CG  1 
ATOM 3421 O OD1 . ASP A 1 455 ? 190.080 172.797 138.082 1.00 10.00 ? 439 ASP A OD1 1 
ATOM 3422 O OD2 . ASP A 1 455 ? 191.746 172.694 136.655 1.00 10.00 ? 439 ASP A OD2 1 
ATOM 3423 N N   . SER A 1 456 ? 189.839 174.309 141.445 1.00 5.35  ? 440 SER A N   1 
ATOM 3424 C CA  . SER A 1 456 ? 189.636 173.591 142.700 1.00 5.35  ? 440 SER A CA  1 
ATOM 3425 C C   . SER A 1 456 ? 188.176 173.170 142.827 1.00 5.35  ? 440 SER A C   1 
ATOM 3426 O O   . SER A 1 456 ? 187.541 173.353 143.866 1.00 5.35  ? 440 SER A O   1 
ATOM 3427 C CB  . SER A 1 456 ? 190.070 174.443 143.891 1.00 5.35  ? 440 SER A CB  1 
ATOM 3428 O OG  . SER A 1 456 ? 190.442 173.629 144.990 1.00 5.35  ? 440 SER A OG  1 
ATOM 3429 N N   . LEU A 1 457 ? 187.623 172.610 141.751 1.00 0.71  ? 441 LEU A N   1 
ATOM 3430 C CA  . LEU A 1 457 ? 186.201 172.290 141.689 1.00 0.71  ? 441 LEU A CA  1 
ATOM 3431 C C   . LEU A 1 457 ? 185.777 171.334 142.800 1.00 0.71  ? 441 LEU A C   1 
ATOM 3432 O O   . LEU A 1 457 ? 186.204 170.176 142.833 1.00 0.71  ? 441 LEU A O   1 
ATOM 3433 C CB  . LEU A 1 457 ? 185.858 171.701 140.320 1.00 0.71  ? 441 LEU A CB  1 
ATOM 3434 C CG  . LEU A 1 457 ? 184.392 171.364 140.050 1.00 0.71  ? 441 LEU A CG  1 
ATOM 3435 C CD1 . LEU A 1 457 ? 183.998 171.830 138.661 1.00 0.71  ? 441 LEU A CD1 1 
ATOM 3436 C CD2 . LEU A 1 457 ? 184.148 169.875 140.195 1.00 0.71  ? 441 LEU A CD2 1 
ATOM 3437 N N   . VAL A 1 458 ? 184.932 171.813 143.705 1.00 0.25  ? 442 VAL A N   1 
ATOM 3438 C CA  . VAL A 1 458 ? 184.466 171.032 144.833 1.00 0.25  ? 442 VAL A CA  1 
ATOM 3439 C C   . VAL A 1 458 ? 183.085 170.478 144.497 1.00 0.25  ? 442 VAL A C   1 
ATOM 3440 O O   . VAL A 1 458 ? 182.408 170.948 143.586 1.00 0.25  ? 442 VAL A O   1 
ATOM 3441 C CB  . VAL A 1 458 ? 184.463 171.878 146.138 1.00 0.25  ? 442 VAL A CB  1 
ATOM 3442 C CG1 . VAL A 1 458 ? 183.972 171.090 147.339 1.00 0.25  ? 442 VAL A CG1 1 
ATOM 3443 C CG2 . VAL A 1 458 ? 185.849 172.403 146.413 1.00 0.25  ? 442 VAL A CG2 1 
ATOM 3444 N N   . CYS A 1 459 ? 182.663 169.453 145.232 1.00 0.32  ? 443 CYS A N   1 
ATOM 3445 C CA  . CYS A 1 459 ? 181.404 168.747 145.016 1.00 0.32  ? 443 CYS A CA  1 
ATOM 3446 C C   . CYS A 1 459 ? 180.579 168.743 146.295 1.00 0.32  ? 443 CYS A C   1 
ATOM 3447 O O   . CYS A 1 459 ? 180.090 167.708 146.749 1.00 0.32  ? 443 CYS A O   1 
ATOM 3448 C CB  . CYS A 1 459 ? 181.666 167.327 144.528 1.00 0.32  ? 443 CYS A CB  1 
ATOM 3449 S SG  . CYS A 1 459 ? 180.294 166.566 143.645 1.00 0.32  ? 443 CYS A SG  1 
ATOM 3450 N N   . TYR A 1 460 ? 180.434 169.922 146.898 1.00 0.68  ? 444 TYR A N   1 
ATOM 3451 C CA  . TYR A 1 460 ? 179.794 170.051 148.202 1.00 0.68  ? 444 TYR A CA  1 
ATOM 3452 C C   . TYR A 1 460 ? 178.385 169.472 148.200 1.00 0.68  ? 444 TYR A C   1 
ATOM 3453 O O   . TYR A 1 460 ? 177.603 169.690 147.271 1.00 0.68  ? 444 TYR A O   1 
ATOM 3454 C CB  . TYR A 1 460 ? 179.756 171.525 148.609 1.00 0.68  ? 444 TYR A CB  1 
ATOM 3455 C CG  . TYR A 1 460 ? 178.792 171.848 149.727 1.00 0.68  ? 444 TYR A CG  1 
ATOM 3456 C CD1 . TYR A 1 460 ? 178.991 171.353 151.006 1.00 0.68  ? 444 TYR A CD1 1 
ATOM 3457 C CD2 . TYR A 1 460 ? 177.691 172.662 149.506 1.00 0.68  ? 444 TYR A CD2 1 
ATOM 3458 C CE1 . TYR A 1 460 ? 178.117 171.651 152.032 1.00 0.68  ? 444 TYR A CE1 1 
ATOM 3459 C CE2 . TYR A 1 460 ? 176.812 172.966 150.525 1.00 0.68  ? 444 TYR A CE2 1 
ATOM 3460 C CZ  . TYR A 1 460 ? 177.030 172.456 151.785 1.00 0.68  ? 444 TYR A CZ  1 
ATOM 3461 O OH  . TYR A 1 460 ? 176.159 172.753 152.806 1.00 0.68  ? 444 TYR A OH  1 
ATOM 3462 N N   . ASN A 1 461 ? 178.067 168.725 149.256 1.00 0.83  ? 445 ASN A N   1 
ATOM 3463 C CA  . ASN A 1 461 ? 176.756 168.114 149.449 1.00 0.83  ? 445 ASN A CA  1 
ATOM 3464 C C   . ASN A 1 461 ? 176.074 168.774 150.638 1.00 0.83  ? 445 ASN A C   1 
ATOM 3465 O O   . ASN A 1 461 ? 176.629 168.755 151.751 1.00 0.83  ? 445 ASN A O   1 
ATOM 3466 C CB  . ASN A 1 461 ? 176.887 166.605 149.675 1.00 0.83  ? 445 ASN A CB  1 
ATOM 3467 C CG  . ASN A 1 461 ? 175.553 165.878 149.599 1.00 0.83  ? 445 ASN A CG  1 
ATOM 3468 O OD1 . ASN A 1 461 ? 174.500 166.454 149.862 1.00 0.83  ? 445 ASN A OD1 1 
ATOM 3469 N ND2 . ASN A 1 461 ? 175.598 164.601 149.246 1.00 0.83  ? 445 ASN A ND2 1 
ATOM 3470 N N   . PRO A 1 462 ? 174.888 169.365 150.471 1.00 1.00  ? 446 PRO A N   1 
ATOM 3471 C CA  . PRO A 1 462 ? 174.247 170.052 151.603 1.00 1.00  ? 446 PRO A CA  1 
ATOM 3472 C C   . PRO A 1 462 ? 173.659 169.116 152.644 1.00 1.00  ? 446 PRO A C   1 
ATOM 3473 O O   . PRO A 1 462 ? 173.413 169.558 153.772 1.00 1.00  ? 446 PRO A O   1 
ATOM 3474 C CB  . PRO A 1 462 ? 173.149 170.892 150.932 1.00 1.00  ? 446 PRO A CB  1 
ATOM 3475 C CG  . PRO A 1 462 ? 173.428 170.824 149.452 1.00 1.00  ? 446 PRO A CG  1 
ATOM 3476 C CD  . PRO A 1 462 ? 174.126 169.531 149.226 1.00 1.00  ? 446 PRO A CD  1 
ATOM 3477 N N   . LEU A 1 463 ? 173.422 167.847 152.313 1.00 3.22  ? 447 LEU A N   1 
ATOM 3478 C CA  . LEU A 1 463 ? 172.775 166.925 153.243 1.00 3.22  ? 447 LEU A CA  1 
ATOM 3479 C C   . LEU A 1 463 ? 173.795 166.156 154.080 1.00 3.22  ? 447 LEU A C   1 
ATOM 3480 O O   . LEU A 1 463 ? 173.634 166.024 155.297 1.00 3.22  ? 447 LEU A O   1 
ATOM 3481 C CB  . LEU A 1 463 ? 171.868 165.957 152.475 1.00 3.22  ? 447 LEU A CB  1 
ATOM 3482 C CG  . LEU A 1 463 ? 170.504 166.512 152.059 1.00 3.22  ? 447 LEU A CG  1 
ATOM 3483 C CD1 . LEU A 1 463 ? 170.003 165.827 150.797 1.00 3.22  ? 447 LEU A CD1 1 
ATOM 3484 C CD2 . LEU A 1 463 ? 169.500 166.364 153.189 1.00 3.22  ? 447 LEU A CD2 1 
ATOM 3485 N N   . LEU A 1 464 ? 174.841 165.636 153.438 1.00 4.27  ? 448 LEU A N   1 
ATOM 3486 C CA  . LEU A 1 464 ? 175.888 164.917 154.155 1.00 4.27  ? 448 LEU A CA  1 
ATOM 3487 C C   . LEU A 1 464 ? 176.944 165.842 154.745 1.00 4.27  ? 448 LEU A C   1 
ATOM 3488 O O   . LEU A 1 464 ? 177.725 165.394 155.592 1.00 4.27  ? 448 LEU A O   1 
ATOM 3489 C CB  . LEU A 1 464 ? 176.558 163.901 153.227 1.00 4.27  ? 448 LEU A CB  1 
ATOM 3490 C CG  . LEU A 1 464 ? 176.100 162.443 153.309 1.00 4.27  ? 448 LEU A CG  1 
ATOM 3491 C CD1 . LEU A 1 464 ? 176.576 161.812 154.603 1.00 4.27  ? 448 LEU A CD1 1 
ATOM 3492 C CD2 . LEU A 1 464 ? 174.590 162.331 153.178 1.00 4.27  ? 448 LEU A CD2 1 
ATOM 3493 N N   . ASP A 1 465 ? 176.976 167.111 154.332 1.00 3.74  ? 449 ASP A N   1 
ATOM 3494 C CA  . ASP A 1 465 ? 177.978 168.081 154.778 1.00 3.74  ? 449 ASP A CA  1 
ATOM 3495 C C   . ASP A 1 465 ? 179.397 167.541 154.586 1.00 3.74  ? 449 ASP A C   1 
ATOM 3496 O O   . ASP A 1 465 ? 180.144 167.320 155.540 1.00 3.74  ? 449 ASP A O   1 
ATOM 3497 C CB  . ASP A 1 465 ? 177.745 168.500 156.236 1.00 3.74  ? 449 ASP A CB  1 
ATOM 3498 C CG  . ASP A 1 465 ? 176.277 168.659 156.577 1.00 3.74  ? 449 ASP A CG  1 
ATOM 3499 O OD1 . ASP A 1 465 ? 175.866 169.792 156.904 1.00 3.74  ? 449 ASP A OD1 1 
ATOM 3500 O OD2 . ASP A 1 465 ? 175.537 167.656 156.540 1.00 3.74  ? 449 ASP A OD2 1 
ATOM 3501 N N   . SER A 1 466 ? 179.759 167.324 153.324 1.00 1.81  ? 450 SER A N   1 
ATOM 3502 C CA  . SER A 1 466 ? 181.096 166.849 153.007 1.00 1.81  ? 450 SER A CA  1 
ATOM 3503 C C   . SER A 1 466 ? 181.559 167.465 151.696 1.00 1.81  ? 450 SER A C   1 
ATOM 3504 O O   . SER A 1 466 ? 180.751 167.779 150.820 1.00 1.81  ? 450 SER A O   1 
ATOM 3505 C CB  . SER A 1 466 ? 181.145 165.321 152.922 1.00 1.81  ? 450 SER A CB  1 
ATOM 3506 O OG  . SER A 1 466 ? 182.410 164.831 153.332 1.00 1.81  ? 450 SER A OG  1 
ATOM 3507 N N   . PHE A 1 467 ? 182.873 167.629 151.575 1.00 2.12  ? 451 PHE A N   1 
ATOM 3508 C CA  . PHE A 1 467 ? 183.505 168.195 150.394 1.00 2.12  ? 451 PHE A CA  1 
ATOM 3509 C C   . PHE A 1 467 ? 184.459 167.175 149.786 1.00 2.12  ? 451 PHE A C   1 
ATOM 3510 O O   . PHE A 1 467 ? 185.268 166.562 150.486 1.00 2.12  ? 451 PHE A O   1 
ATOM 3511 C CB  . PHE A 1 467 ? 184.264 169.482 150.731 1.00 2.12  ? 451 PHE A CB  1 
ATOM 3512 C CG  . PHE A 1 467 ? 183.427 170.519 151.425 1.00 2.12  ? 451 PHE A CG  1 
ATOM 3513 C CD1 . PHE A 1 467 ? 183.159 170.425 152.779 1.00 2.12  ? 451 PHE A CD1 1 
ATOM 3514 C CD2 . PHE A 1 467 ? 182.907 171.588 150.720 1.00 2.12  ? 451 PHE A CD2 1 
ATOM 3515 C CE1 . PHE A 1 467 ? 182.389 171.376 153.415 1.00 2.12  ? 451 PHE A CE1 1 
ATOM 3516 C CE2 . PHE A 1 467 ? 182.138 172.541 151.350 1.00 2.12  ? 451 PHE A CE2 1 
ATOM 3517 C CZ  . PHE A 1 467 ? 181.878 172.435 152.699 1.00 2.12  ? 451 PHE A CZ  1 
ATOM 3518 N N   . THR A 1 468 ? 184.356 167.000 148.471 1.00 2.03  ? 452 THR A N   1 
ATOM 3519 C CA  . THR A 1 468 ? 185.052 165.931 147.757 1.00 2.03  ? 452 THR A CA  1 
ATOM 3520 C C   . THR A 1 468 ? 185.786 166.498 146.549 1.00 2.03  ? 452 THR A C   1 
ATOM 3521 O O   . THR A 1 468 ? 185.649 166.006 145.428 1.00 2.03  ? 452 THR A O   1 
ATOM 3522 C CB  . THR A 1 468 ? 184.087 164.835 147.315 1.00 2.03  ? 452 THR A CB  1 
ATOM 3523 O OG1 . THR A 1 468 ? 183.499 165.200 146.061 1.00 2.03  ? 452 THR A OG1 1 
ATOM 3524 C CG2 . THR A 1 468 ? 182.989 164.655 148.336 1.00 2.03  ? 452 THR A CG2 1 
ATOM 3525 N N   . ARG A 1 469 ? 186.565 167.557 146.772 1.00 3.34  ? 453 ARG A N   1 
ATOM 3526 C CA  . ARG A 1 469 ? 187.169 168.326 145.689 1.00 3.34  ? 453 ARG A CA  1 
ATOM 3527 C C   . ARG A 1 469 ? 187.910 167.445 144.691 1.00 3.34  ? 453 ARG A C   1 
ATOM 3528 O O   . ARG A 1 469 ? 188.939 166.845 145.016 1.00 3.34  ? 453 ARG A O   1 
ATOM 3529 C CB  . ARG A 1 469 ? 188.123 169.380 146.257 1.00 3.34  ? 453 ARG A CB  1 
ATOM 3530 C CG  . ARG A 1 469 ? 188.936 168.913 147.451 1.00 3.34  ? 453 ARG A CG  1 
ATOM 3531 C CD  . ARG A 1 469 ? 190.177 169.770 147.636 1.00 3.34  ? 453 ARG A CD  1 
ATOM 3532 N NE  . ARG A 1 469 ? 189.873 171.195 147.579 1.00 3.34  ? 453 ARG A NE  1 
ATOM 3533 C CZ  . ARG A 1 469 ? 190.776 172.159 147.693 1.00 3.34  ? 453 ARG A CZ  1 
ATOM 3534 N NH1 . ARG A 1 469 ? 192.058 171.888 147.874 1.00 3.34  ? 453 ARG A NH1 1 
ATOM 3535 N NH2 . ARG A 1 469 ? 190.383 173.427 147.624 1.00 3.34  ? 453 ARG A NH2 1 
ATOM 3536 N N   . LEU A 1 470 ? 187.381 167.368 143.473 1.00 4.85  ? 454 LEU A N   1 
ATOM 3537 C CA  . LEU A 1 470 ? 187.995 166.594 142.396 1.00 4.85  ? 454 LEU A CA  1 
ATOM 3538 C C   . LEU A 1 470 ? 188.820 167.527 141.509 1.00 4.85  ? 454 LEU A C   1 
ATOM 3539 O O   . LEU A 1 470 ? 188.498 167.823 140.360 1.00 4.85  ? 454 LEU A O   1 
ATOM 3540 C CB  . LEU A 1 470 ? 186.919 165.811 141.636 1.00 4.85  ? 454 LEU A CB  1 
ATOM 3541 C CG  . LEU A 1 470 ? 185.680 166.419 140.956 1.00 4.85  ? 454 LEU A CG  1 
ATOM 3542 C CD1 . LEU A 1 470 ? 185.889 166.797 139.492 1.00 4.85  ? 454 LEU A CD1 1 
ATOM 3543 C CD2 . LEU A 1 470 ? 184.488 165.478 141.102 1.00 4.85  ? 454 LEU A CD2 1 
ATOM 3544 N N   . CYS A 1 471 ? 189.921 167.997 142.093 1.00 8.60  ? 455 CYS A N   1 
ATOM 3545 C CA  . CYS A 1 471 ? 190.790 168.950 141.416 1.00 8.60  ? 455 CYS A CA  1 
ATOM 3546 C C   . CYS A 1 471 ? 191.311 168.376 140.105 1.00 8.60  ? 455 CYS A C   1 
ATOM 3547 O O   . CYS A 1 471 ? 191.784 167.237 140.051 1.00 8.60  ? 455 CYS A O   1 
ATOM 3548 C CB  . CYS A 1 471 ? 191.958 169.332 142.326 1.00 8.60  ? 455 CYS A CB  1 
ATOM 3549 S SG  . CYS A 1 471 ? 193.134 170.487 141.586 1.00 8.60  ? 455 CYS A SG  1 
ATOM 3550 N N   . LEU A 1 472 ? 191.212 169.172 139.044 1.00 12.31 ? 456 LEU A N   1 
ATOM 3551 C CA  . LEU A 1 472 ? 191.693 168.763 137.739 1.00 12.31 ? 456 LEU A CA  1 
ATOM 3552 C C   . LEU A 1 472 ? 193.216 168.860 137.684 1.00 12.31 ? 456 LEU A C   1 
ATOM 3553 O O   . LEU A 1 472 ? 193.832 169.550 138.500 1.00 12.31 ? 456 LEU A O   1 
ATOM 3554 C CB  . LEU A 1 472 ? 191.063 169.631 136.654 1.00 12.31 ? 456 LEU A CB  1 
ATOM 3555 C CG  . LEU A 1 472 ? 189.550 169.810 136.775 1.00 12.31 ? 456 LEU A CG  1 
ATOM 3556 C CD1 . LEU A 1 472 ? 189.015 170.699 135.663 1.00 12.31 ? 456 LEU A CD1 1 
ATOM 3557 C CD2 . LEU A 1 472 ? 188.865 168.455 136.775 1.00 12.31 ? 456 LEU A CD2 1 
ATOM 3558 N N   . PRO A 1 473 ? 193.849 168.159 136.741 1.00 17.60 ? 457 PRO A N   1 
ATOM 3559 C CA  . PRO A 1 473 ? 195.304 168.285 136.591 1.00 17.60 ? 457 PRO A CA  1 
ATOM 3560 C C   . PRO A 1 473 ? 195.709 169.725 136.316 1.00 17.60 ? 457 PRO A C   1 
ATOM 3561 O O   . PRO A 1 473 ? 195.034 170.454 135.587 1.00 17.60 ? 457 PRO A O   1 
ATOM 3562 C CB  . PRO A 1 473 ? 195.619 167.373 135.400 1.00 17.60 ? 457 PRO A CB  1 
ATOM 3563 C CG  . PRO A 1 473 ? 194.515 166.377 135.391 1.00 17.60 ? 457 PRO A CG  1 
ATOM 3564 C CD  . PRO A 1 473 ? 193.294 167.106 135.872 1.00 17.60 ? 457 PRO A CD  1 
ATOM 3565 N N   . GLU A 1 474 ? 196.829 170.129 136.910 1.00 17.90 ? 458 GLU A N   1 
ATOM 3566 C CA  . GLU A 1 474 ? 197.309 171.502 136.825 1.00 17.90 ? 458 GLU A CA  1 
ATOM 3567 C C   . GLU A 1 474 ? 197.999 171.814 135.502 1.00 17.90 ? 458 GLU A C   1 
ATOM 3568 O O   . GLU A 1 474 ? 198.643 172.864 135.393 1.00 17.90 ? 458 GLU A O   1 
ATOM 3569 C CB  . GLU A 1 474 ? 198.259 171.797 137.989 1.00 17.90 ? 458 GLU A CB  1 
ATOM 3570 C CG  . GLU A 1 474 ? 197.648 171.555 139.360 1.00 17.90 ? 458 GLU A CG  1 
ATOM 3571 C CD  . GLU A 1 474 ? 198.653 171.712 140.484 1.00 17.90 ? 458 GLU A CD  1 
ATOM 3572 O OE1 . GLU A 1 474 ? 199.820 171.305 140.302 1.00 17.90 ? 458 GLU A OE1 1 
ATOM 3573 O OE2 . GLU A 1 474 ? 198.276 172.242 141.551 1.00 17.90 ? 458 GLU A OE2 1 
ATOM 3574 N N   . ALA A 1 475 ? 197.890 170.933 134.505 1.00 19.06 ? 459 ALA A N   1 
ATOM 3575 C CA  . ALA A 1 475 ? 198.496 171.209 133.207 1.00 19.06 ? 459 ALA A CA  1 
ATOM 3576 C C   . ALA A 1 475 ? 197.851 172.419 132.542 1.00 19.06 ? 459 ALA A C   1 
ATOM 3577 O O   . ALA A 1 475 ? 198.547 173.275 131.984 1.00 19.06 ? 459 ALA A O   1 
ATOM 3578 C CB  . ALA A 1 475 ? 198.389 169.980 132.305 1.00 19.06 ? 459 ALA A CB  1 
ATOM 3579 N N   . TRP A 1 476 ? 196.526 172.509 132.592 1.00 15.48 ? 460 TRP A N   1 
ATOM 3580 C CA  . TRP A 1 476 ? 195.798 173.633 132.002 1.00 15.48 ? 460 TRP A CA  1 
ATOM 3581 C C   . TRP A 1 476 ? 195.501 174.694 133.061 1.00 15.48 ? 460 TRP A C   1 
ATOM 3582 O O   . TRP A 1 476 ? 194.354 175.052 133.329 1.00 15.48 ? 460 TRP A O   1 
ATOM 3583 C CB  . TRP A 1 476 ? 194.519 173.141 131.333 1.00 15.48 ? 460 TRP A CB  1 
ATOM 3584 C CG  . TRP A 1 476 ? 194.290 173.733 129.975 1.00 15.48 ? 460 TRP A CG  1 
ATOM 3585 C CD1 . TRP A 1 476 ? 193.636 174.895 129.686 1.00 15.48 ? 460 TRP A CD1 1 
ATOM 3586 C CD2 . TRP A 1 476 ? 194.714 173.188 128.719 1.00 15.48 ? 460 TRP A CD2 1 
ATOM 3587 N NE1 . TRP A 1 476 ? 193.627 175.109 128.329 1.00 15.48 ? 460 TRP A NE1 1 
ATOM 3588 C CE2 . TRP A 1 476 ? 194.282 174.075 127.713 1.00 15.48 ? 460 TRP A CE2 1 
ATOM 3589 C CE3 . TRP A 1 476 ? 195.416 172.038 128.348 1.00 15.48 ? 460 TRP A CE3 1 
ATOM 3590 C CZ2 . TRP A 1 476 ? 194.529 173.848 126.361 1.00 15.48 ? 460 TRP A CZ2 1 
ATOM 3591 C CZ3 . TRP A 1 476 ? 195.661 171.814 127.005 1.00 15.48 ? 460 TRP A CZ3 1 
ATOM 3592 C CH2 . TRP A 1 476 ? 195.218 172.715 126.028 1.00 15.48 ? 460 TRP A CH2 1 
ATOM 3593 N N   . SER A 1 477 ? 196.571 175.196 133.671 1.00 18.35 ? 461 SER A N   1 
ATOM 3594 C CA  . SER A 1 477 ? 196.485 176.245 134.683 1.00 18.35 ? 461 SER A CA  1 
ATOM 3595 C C   . SER A 1 477 ? 197.548 177.304 134.412 1.00 18.35 ? 461 SER A C   1 
ATOM 3596 O O   . SER A 1 477 ? 198.283 177.728 135.305 1.00 18.35 ? 461 SER A O   1 
ATOM 3597 C CB  . SER A 1 477 ? 196.626 175.662 136.087 1.00 18.35 ? 461 SER A CB  1 
ATOM 3598 O OG  . SER A 1 477 ? 195.713 174.599 136.291 1.00 18.35 ? 461 SER A OG  1 
ATOM 3599 N N   . SER A 1 478 ? 197.640 177.736 133.152 1.00 18.92 ? 462 SER A N   1 
ATOM 3600 C CA  . SER A 1 478 ? 198.663 178.704 132.766 1.00 18.92 ? 462 SER A CA  1 
ATOM 3601 C C   . SER A 1 478 ? 198.455 180.046 133.457 1.00 18.92 ? 462 SER A C   1 
ATOM 3602 O O   . SER A 1 478 ? 199.421 180.673 133.908 1.00 18.92 ? 462 SER A O   1 
ATOM 3603 C CB  . SER A 1 478 ? 198.669 178.879 131.247 1.00 18.92 ? 462 SER A CB  1 
ATOM 3604 O OG  . SER A 1 478 ? 197.435 179.405 130.790 1.00 18.92 ? 462 SER A OG  1 
ATOM 3605 N N   . ALA A 1 479 ? 197.212 180.503 133.550 1.00 16.46 ? 463 ALA A N   1 
ATOM 3606 C CA  . ALA A 1 479 ? 196.909 181.799 134.134 1.00 16.46 ? 463 ALA A CA  1 
ATOM 3607 C C   . ALA A 1 479 ? 195.812 181.664 135.177 1.00 16.46 ? 463 ALA A C   1 
ATOM 3608 O O   . ALA A 1 479 ? 194.961 180.774 135.080 1.00 16.46 ? 463 ALA A O   1 
ATOM 3609 C CB  . ALA A 1 479 ? 196.472 182.801 133.055 1.00 16.46 ? 463 ALA A CB  1 
ATOM 3610 N N   . PRO A 1 480 ? 195.807 182.536 136.190 1.00 16.74 ? 464 PRO A N   1 
ATOM 3611 C CA  . PRO A 1 480 ? 194.740 182.513 137.208 1.00 16.74 ? 464 PRO A CA  1 
ATOM 3612 C C   . PRO A 1 480 ? 193.439 183.125 136.698 1.00 16.74 ? 464 PRO A C   1 
ATOM 3613 O O   . PRO A 1 480 ? 192.987 184.177 137.159 1.00 16.74 ? 464 PRO A O   1 
ATOM 3614 C CB  . PRO A 1 480 ? 195.366 183.322 138.351 1.00 16.74 ? 464 PRO A CB  1 
ATOM 3615 C CG  . PRO A 1 480 ? 196.252 184.294 137.655 1.00 16.74 ? 464 PRO A CG  1 
ATOM 3616 C CD  . PRO A 1 480 ? 196.856 183.518 136.518 1.00 16.74 ? 464 PRO A CD  1 
ATOM 3617 N N   . SER A 1 481 ? 192.823 182.455 135.729 1.00 11.09 ? 465 SER A N   1 
ATOM 3618 C CA  . SER A 1 481 ? 191.593 182.924 135.106 1.00 11.09 ? 465 SER A CA  1 
ATOM 3619 C C   . SER A 1 481 ? 190.399 182.239 135.756 1.00 11.09 ? 465 SER A C   1 
ATOM 3620 O O   . SER A 1 481 ? 190.406 181.019 135.948 1.00 11.09 ? 465 SER A O   1 
ATOM 3621 C CB  . SER A 1 481 ? 191.606 182.651 133.602 1.00 11.09 ? 465 SER A CB  1 
ATOM 3622 O OG  . SER A 1 481 ? 190.465 183.210 132.976 1.00 11.09 ? 465 SER A OG  1 
ATOM 3623 N N   . LEU A 1 482 ? 189.382 183.028 136.096 1.00 9.82  ? 466 LEU A N   1 
ATOM 3624 C CA  . LEU A 1 482 ? 188.191 182.480 136.729 1.00 9.82  ? 466 LEU A CA  1 
ATOM 3625 C C   . LEU A 1 482 ? 187.469 181.533 135.780 1.00 9.82  ? 466 LEU A C   1 
ATOM 3626 O O   . LEU A 1 482 ? 187.428 181.752 134.567 1.00 9.82  ? 466 LEU A O   1 
ATOM 3627 C CB  . LEU A 1 482 ? 187.252 183.607 137.160 1.00 9.82  ? 466 LEU A CB  1 
ATOM 3628 C CG  . LEU A 1 482 ? 187.692 184.458 138.352 1.00 9.82  ? 466 LEU A CG  1 
ATOM 3629 C CD1 . LEU A 1 482 ? 186.702 185.586 138.595 1.00 9.82  ? 466 LEU A CD1 1 
ATOM 3630 C CD2 . LEU A 1 482 ? 187.837 183.597 139.593 1.00 9.82  ? 466 LEU A CD2 1 
ATOM 3631 N N   . TRP A 1 483 ? 186.903 180.470 136.342 1.00 4.99  ? 467 TRP A N   1 
ATOM 3632 C CA  . TRP A 1 483 ? 186.157 179.476 135.584 1.00 4.99  ? 467 TRP A CA  1 
ATOM 3633 C C   . TRP A 1 483 ? 184.676 179.614 135.906 1.00 4.99  ? 467 TRP A C   1 
ATOM 3634 O O   . TRP A 1 483 ? 184.255 179.336 137.033 1.00 4.99  ? 467 TRP A O   1 
ATOM 3635 C CB  . TRP A 1 483 ? 186.639 178.062 135.907 1.00 4.99  ? 467 TRP A CB  1 
ATOM 3636 C CG  . TRP A 1 483 ? 188.057 177.797 135.525 1.00 4.99  ? 467 TRP A CG  1 
ATOM 3637 C CD1 . TRP A 1 483 ? 189.170 178.091 136.253 1.00 4.99  ? 467 TRP A CD1 1 
ATOM 3638 C CD2 . TRP A 1 483 ? 188.516 177.168 134.324 1.00 4.99  ? 467 TRP A CD2 1 
ATOM 3639 N NE1 . TRP A 1 483 ? 190.297 177.691 135.577 1.00 4.99  ? 467 TRP A NE1 1 
ATOM 3640 C CE2 . TRP A 1 483 ? 189.922 177.120 134.390 1.00 4.99  ? 467 TRP A CE2 1 
ATOM 3641 C CE3 . TRP A 1 483 ? 187.876 176.643 133.199 1.00 4.99  ? 467 TRP A CE3 1 
ATOM 3642 C CZ2 . TRP A 1 483 ? 190.697 176.570 133.374 1.00 4.99  ? 467 TRP A CZ2 1 
ATOM 3643 C CZ3 . TRP A 1 483 ? 188.647 176.098 132.192 1.00 4.99  ? 467 TRP A CZ3 1 
ATOM 3644 C CH2 . TRP A 1 483 ? 190.042 176.065 132.286 1.00 4.99  ? 467 TRP A CH2 1 
ATOM 3645 N N   . LYS A 1 484 ? 183.894 180.043 134.921 1.00 1.63  ? 468 LYS A N   1 
ATOM 3646 C CA  . LYS A 1 484 ? 182.446 180.042 135.058 1.00 1.63  ? 468 LYS A CA  1 
ATOM 3647 C C   . LYS A 1 484 ? 181.915 178.633 134.842 1.00 1.63  ? 468 LYS A C   1 
ATOM 3648 O O   . LYS A 1 484 ? 182.401 177.898 133.979 1.00 1.63  ? 468 LYS A O   1 
ATOM 3649 C CB  . LYS A 1 484 ? 181.811 181.006 134.058 1.00 1.63  ? 468 LYS A CB  1 
ATOM 3650 C CG  . LYS A 1 484 ? 181.460 182.363 134.639 1.00 1.63  ? 468 LYS A CG  1 
ATOM 3651 C CD  . LYS A 1 484 ? 182.699 183.200 134.891 1.00 1.63  ? 468 LYS A CD  1 
ATOM 3652 C CE  . LYS A 1 484 ? 182.328 184.636 135.219 1.00 1.63  ? 468 LYS A CE  1 
ATOM 3653 N NZ  . LYS A 1 484 ? 183.526 185.467 135.514 1.00 1.63  ? 468 LYS A NZ  1 
ATOM 3654 N N   . ILE A 1 485 ? 180.918 178.253 135.634 1.00 0.19  ? 469 ILE A N   1 
ATOM 3655 C CA  . ILE A 1 485 ? 180.368 176.904 135.607 1.00 0.19  ? 469 ILE A CA  1 
ATOM 3656 C C   . ILE A 1 485 ? 178.859 176.983 135.424 1.00 0.19  ? 469 ILE A C   1 
ATOM 3657 O O   . ILE A 1 485 ? 178.183 177.784 136.078 1.00 0.19  ? 469 ILE A O   1 
ATOM 3658 C CB  . ILE A 1 485 ? 180.741 176.122 136.884 1.00 0.19  ? 469 ILE A CB  1 
ATOM 3659 C CG1 . ILE A 1 485 ? 180.057 174.756 136.906 1.00 0.19  ? 469 ILE A CG1 1 
ATOM 3660 C CG2 . ILE A 1 485 ? 180.405 176.924 138.127 1.00 0.19  ? 469 ILE A CG2 1 
ATOM 3661 C CD1 . ILE A 1 485 ? 180.323 173.972 138.163 1.00 0.19  ? 469 ILE A CD1 1 
ATOM 3662 N N   . ALA A 1 486 ? 178.336 176.161 134.515 1.00 0.15  ? 470 ALA A N   1 
ATOM 3663 C CA  . ALA A 1 486 ? 176.910 176.106 134.228 1.00 0.15  ? 470 ALA A CA  1 
ATOM 3664 C C   . ALA A 1 486 ? 176.481 174.656 134.083 1.00 0.15  ? 470 ALA A C   1 
ATOM 3665 O O   . ALA A 1 486 ? 177.207 173.843 133.506 1.00 0.15  ? 470 ALA A O   1 
ATOM 3666 C CB  . ALA A 1 486 ? 176.563 176.873 132.949 1.00 0.15  ? 470 ALA A CB  1 
ATOM 3667 N N   . SER A 1 487 ? 175.298 174.339 134.598 1.00 0.32  ? 471 SER A N   1 
ATOM 3668 C CA  . SER A 1 487 ? 174.749 172.991 134.549 1.00 0.32  ? 471 SER A CA  1 
ATOM 3669 C C   . SER A 1 487 ? 173.522 172.969 133.650 1.00 0.32  ? 471 SER A C   1 
ATOM 3670 O O   . SER A 1 487 ? 172.584 173.746 133.856 1.00 0.32  ? 471 SER A O   1 
ATOM 3671 C CB  . SER A 1 487 ? 174.382 172.498 135.949 1.00 0.32  ? 471 SER A CB  1 
ATOM 3672 O OG  . SER A 1 487 ? 173.464 171.422 135.881 1.00 0.32  ? 471 SER A OG  1 
ATOM 3673 N N   . CYS A 1 488 ? 173.528 172.078 132.661 1.00 4.70  ? 472 CYS A N   1 
ATOM 3674 C CA  . CYS A 1 488 ? 172.402 171.939 131.750 1.00 4.70  ? 472 CYS A CA  1 
ATOM 3675 C C   . CYS A 1 488 ? 172.397 170.533 131.172 1.00 4.70  ? 472 CYS A C   1 
ATOM 3676 O O   . CYS A 1 488 ? 173.456 169.979 130.863 1.00 4.70  ? 472 CYS A O   1 
ATOM 3677 C CB  . CYS A 1 488 ? 172.465 172.971 130.620 1.00 4.70  ? 472 CYS A CB  1 
ATOM 3678 S SG  . CYS A 1 488 ? 174.019 172.964 129.705 1.00 4.70  ? 472 CYS A SG  1 
ATOM 3679 N N   . ASN A 1 489 ? 171.197 169.967 131.029 1.00 6.25  ? 473 ASN A N   1 
ATOM 3680 C CA  . ASN A 1 489 ? 171.001 168.637 130.451 1.00 6.25  ? 473 ASN A CA  1 
ATOM 3681 C C   . ASN A 1 489 ? 171.799 167.566 131.191 1.00 6.25  ? 473 ASN A C   1 
ATOM 3682 O O   . ASN A 1 489 ? 172.348 166.650 130.575 1.00 6.25  ? 473 ASN A O   1 
ATOM 3683 C CB  . ASN A 1 489 ? 171.348 168.622 128.960 1.00 6.25  ? 473 ASN A CB  1 
ATOM 3684 C CG  . ASN A 1 489 ? 170.192 168.155 128.098 1.00 6.25  ? 473 ASN A CG  1 
ATOM 3685 O OD1 . ASN A 1 489 ? 169.036 168.186 128.520 1.00 6.25  ? 473 ASN A OD1 1 
ATOM 3686 N ND2 . ASN A 1 489 ? 170.499 167.716 126.883 1.00 6.25  ? 473 ASN A ND2 1 
ATOM 3687 N N   . GLY A 1 490 ? 171.870 167.673 132.514 1.00 7.59  ? 474 GLY A N   1 
ATOM 3688 C CA  . GLY A 1 490 ? 172.535 166.664 133.322 1.00 7.59  ? 474 GLY A CA  1 
ATOM 3689 C C   . GLY A 1 490 ? 174.014 166.498 133.051 1.00 7.59  ? 474 GLY A C   1 
ATOM 3690 O O   . GLY A 1 490 ? 174.538 165.382 133.161 1.00 7.59  ? 474 GLY A O   1 
ATOM 3691 N N   . SER A 1 491 ? 174.703 167.580 132.697 1.00 4.76  ? 475 SER A N   1 
ATOM 3692 C CA  . SER A 1 491 ? 176.149 167.541 132.489 1.00 4.76  ? 475 SER A CA  1 
ATOM 3693 C C   . SER A 1 491 ? 176.664 168.967 132.549 1.00 4.76  ? 475 SER A C   1 
ATOM 3694 O O   . SER A 1 491 ? 176.320 169.781 131.688 1.00 4.76  ? 475 SER A O   1 
ATOM 3695 C CB  . SER A 1 491 ? 176.495 166.893 131.150 1.00 4.76  ? 475 SER A CB  1 
ATOM 3696 O OG  . SER A 1 491 ? 175.857 167.570 130.082 1.00 4.76  ? 475 SER A OG  1 
ATOM 3697 N N   . ILE A 1 492 ? 177.482 169.272 133.557 1.00 0.85  ? 476 ILE A N   1 
ATOM 3698 C CA  . ILE A 1 492 ? 177.920 170.646 133.759 1.00 0.85  ? 476 ILE A CA  1 
ATOM 3699 C C   . ILE A 1 492 ? 178.963 171.017 132.713 1.00 0.85  ? 476 ILE A C   1 
ATOM 3700 O O   . ILE A 1 492 ? 179.792 170.191 132.308 1.00 0.85  ? 476 ILE A O   1 
ATOM 3701 C CB  . ILE A 1 492 ? 178.454 170.844 135.188 1.00 0.85  ? 476 ILE A CB  1 
ATOM 3702 C CG1 . ILE A 1 492 ? 179.801 170.155 135.379 1.00 0.85  ? 476 ILE A CG1 1 
ATOM 3703 C CG2 . ILE A 1 492 ? 177.457 170.319 136.203 1.00 0.85  ? 476 ILE A CG2 1 
ATOM 3704 C CD1 . ILE A 1 492 ? 180.541 170.648 136.594 1.00 0.85  ? 476 ILE A CD1 1 
ATOM 3705 N N   . TYR A 1 493 ? 178.907 172.263 132.253 1.00 1.13  ? 477 TYR A N   1 
ATOM 3706 C CA  . TYR A 1 493 ? 179.821 172.798 131.247 1.00 1.13  ? 477 TYR A CA  1 
ATOM 3707 C C   . TYR A 1 493 ? 180.631 173.913 131.902 1.00 1.13  ? 477 TYR A C   1 
ATOM 3708 O O   . TYR A 1 493 ? 180.216 175.072 131.907 1.00 1.13  ? 477 TYR A O   1 
ATOM 3709 C CB  . TYR A 1 493 ? 179.060 173.323 130.034 1.00 1.13  ? 477 TYR A CB  1 
ATOM 3710 C CG  . TYR A 1 493 ? 178.541 172.259 129.099 1.00 1.13  ? 477 TYR A CG  1 
ATOM 3711 C CD1 . TYR A 1 493 ? 177.368 171.576 129.379 1.00 1.13  ? 477 TYR A CD1 1 
ATOM 3712 C CD2 . TYR A 1 493 ? 179.212 171.954 127.925 1.00 1.13  ? 477 TYR A CD2 1 
ATOM 3713 C CE1 . TYR A 1 493 ? 176.886 170.608 128.525 1.00 1.13  ? 477 TYR A CE1 1 
ATOM 3714 C CE2 . TYR A 1 493 ? 178.737 170.989 127.062 1.00 1.13  ? 477 TYR A CE2 1 
ATOM 3715 C CZ  . TYR A 1 493 ? 177.574 170.318 127.368 1.00 1.13  ? 477 TYR A CZ  1 
ATOM 3716 O OH  . TYR A 1 493 ? 177.096 169.353 126.513 1.00 1.13  ? 477 TYR A OH  1 
ATOM 3717 N N   . VAL A 1 494 ? 181.790 173.562 132.453 1.00 1.59  ? 478 VAL A N   1 
ATOM 3718 C CA  . VAL A 1 494 ? 182.655 174.575 133.049 1.00 1.59  ? 478 VAL A CA  1 
ATOM 3719 C C   . VAL A 1 494 ? 183.215 175.445 131.924 1.00 1.59  ? 478 VAL A C   1 
ATOM 3720 O O   . VAL A 1 494 ? 183.924 174.965 131.037 1.00 1.59  ? 478 VAL A O   1 
ATOM 3721 C CB  . VAL A 1 494 ? 183.765 173.949 133.904 1.00 1.59  ? 478 VAL A CB  1 
ATOM 3722 C CG1 . VAL A 1 494 ? 183.154 173.216 135.082 1.00 1.59  ? 478 VAL A CG1 1 
ATOM 3723 C CG2 . VAL A 1 494 ? 184.605 172.973 133.102 1.00 1.59  ? 478 VAL A CG2 1 
ATOM 3724 N N   . PHE A 1 495 ? 182.861 176.727 131.938 1.00 2.41  ? 479 PHE A N   1 
ATOM 3725 C CA  . PHE A 1 495 ? 183.240 177.631 130.867 1.00 2.41  ? 479 PHE A CA  1 
ATOM 3726 C C   . PHE A 1 495 ? 184.606 178.246 131.154 1.00 2.41  ? 479 PHE A C   1 
ATOM 3727 O O   . PHE A 1 495 ? 185.271 177.926 132.142 1.00 2.41  ? 479 PHE A O   1 
ATOM 3728 C CB  . PHE A 1 495 ? 182.176 178.708 130.681 1.00 2.41  ? 479 PHE A CB  1 
ATOM 3729 C CG  . PHE A 1 495 ? 181.043 178.287 129.795 1.00 2.41  ? 479 PHE A CG  1 
ATOM 3730 C CD1 . PHE A 1 495 ? 181.284 177.574 128.635 1.00 2.41  ? 479 PHE A CD1 1 
ATOM 3731 C CD2 . PHE A 1 495 ? 179.737 178.596 130.124 1.00 2.41  ? 479 PHE A CD2 1 
ATOM 3732 C CE1 . PHE A 1 495 ? 180.244 177.183 127.819 1.00 2.41  ? 479 PHE A CE1 1 
ATOM 3733 C CE2 . PHE A 1 495 ? 178.693 178.207 129.312 1.00 2.41  ? 479 PHE A CE2 1 
ATOM 3734 C CZ  . PHE A 1 495 ? 178.948 177.500 128.159 1.00 2.41  ? 479 PHE A CZ  1 
ATOM 3735 N N   . ARG A 1 496 ? 185.033 179.144 130.272 1.00 9.26  ? 480 ARG A N   1 
ATOM 3736 C CA  . ARG A 1 496 ? 186.329 179.790 130.393 1.00 9.26  ? 480 ARG A CA  1 
ATOM 3737 C C   . ARG A 1 496 ? 186.178 181.274 130.095 1.00 9.26  ? 480 ARG A C   1 
ATOM 3738 O O   . ARG A 1 496 ? 185.348 181.678 129.278 1.00 9.26  ? 480 ARG A O   1 
ATOM 3739 C CB  . ARG A 1 496 ? 187.357 179.155 129.445 1.00 9.26  ? 480 ARG A CB  1 
ATOM 3740 C CG  . ARG A 1 496 ? 188.769 179.701 129.577 1.00 9.26  ? 480 ARG A CG  1 
ATOM 3741 C CD  . ARG A 1 496 ? 189.350 179.400 130.947 1.00 9.26  ? 480 ARG A CD  1 
ATOM 3742 N NE  . ARG A 1 496 ? 190.572 180.154 131.198 1.00 9.26  ? 480 ARG A NE  1 
ATOM 3743 C CZ  . ARG A 1 496 ? 191.783 179.766 130.824 1.00 9.26  ? 480 ARG A CZ  1 
ATOM 3744 N NH1 . ARG A 1 496 ? 191.975 178.628 130.179 1.00 9.26  ? 480 ARG A NH1 1 
ATOM 3745 N NH2 . ARG A 1 496 ? 192.827 180.540 131.106 1.00 9.26  ? 480 ARG A NH2 1 
ATOM 3746 N N   . ASP A 1 497 ? 186.993 182.080 130.768 1.00 12.27 ? 481 ASP A N   1 
ATOM 3747 C CA  . ASP A 1 497 ? 187.052 183.509 130.518 1.00 12.27 ? 481 ASP A CA  1 
ATOM 3748 C C   . ASP A 1 497 ? 187.889 183.777 129.269 1.00 12.27 ? 481 ASP A C   1 
ATOM 3749 O O   . ASP A 1 497 ? 188.160 182.880 128.467 1.00 12.27 ? 481 ASP A O   1 
ATOM 3750 C CB  . ASP A 1 497 ? 187.615 184.245 131.733 1.00 12.27 ? 481 ASP A CB  1 
ATOM 3751 C CG  . ASP A 1 497 ? 186.615 184.347 132.865 1.00 12.27 ? 481 ASP A CG  1 
ATOM 3752 O OD1 . ASP A 1 497 ? 185.412 184.120 132.619 1.00 12.27 ? 481 ASP A OD1 1 
ATOM 3753 O OD2 . ASP A 1 497 ? 187.031 184.656 134.001 1.00 12.27 ? 481 ASP A OD2 1 
ATOM 3754 N N   . ARG A 1 498 ? 188.279 185.037 129.088 1.00 18.76 ? 482 ARG A N   1 
ATOM 3755 C CA  . ARG A 1 498 ? 189.091 185.458 127.954 1.00 18.76 ? 482 ARG A CA  1 
ATOM 3756 C C   . ARG A 1 498 ? 190.307 184.561 127.771 1.00 18.76 ? 482 ARG A C   1 
ATOM 3757 O O   . ARG A 1 498 ? 191.101 184.371 128.698 1.00 18.76 ? 482 ARG A O   1 
ATOM 3758 C CB  . ARG A 1 498 ? 189.533 186.910 128.152 1.00 18.76 ? 482 ARG A CB  1 
ATOM 3759 C CG  . ARG A 1 498 ? 189.961 187.239 129.574 1.00 18.76 ? 482 ARG A CG  1 
ATOM 3760 C CD  . ARG A 1 498 ? 190.590 188.620 129.655 1.00 18.76 ? 482 ARG A CD  1 
ATOM 3761 N NE  . ARG A 1 498 ? 191.620 188.809 128.640 1.00 18.76 ? 482 ARG A NE  1 
ATOM 3762 C CZ  . ARG A 1 498 ? 192.922 188.703 128.864 1.00 18.76 ? 482 ARG A CZ  1 
ATOM 3763 N NH1 . ARG A 1 498 ? 193.395 188.409 130.064 1.00 18.76 ? 482 ARG A NH1 1 
ATOM 3764 N NH2 . ARG A 1 498 ? 193.772 188.896 127.859 1.00 18.76 ? 482 ARG A NH2 1 
ATOM 3765 N N   . TYR A 1 499 ? 190.449 184.004 126.573 1.00 25.19 ? 483 TYR A N   1 
ATOM 3766 C CA  . TYR A 1 499 ? 191.539 183.098 126.248 1.00 25.19 ? 483 TYR A CA  1 
ATOM 3767 C C   . TYR A 1 499 ? 192.641 183.841 125.500 1.00 25.19 ? 483 TYR A C   1 
ATOM 3768 O O   . TYR A 1 499 ? 192.400 184.841 124.820 1.00 25.19 ? 483 TYR A O   1 
ATOM 3769 C CB  . TYR A 1 499 ? 191.032 181.919 125.411 1.00 25.19 ? 483 TYR A CB  1 
ATOM 3770 C CG  . TYR A 1 499 ? 192.040 180.803 125.233 1.00 25.19 ? 483 TYR A CG  1 
ATOM 3771 C CD1 . TYR A 1 499 ? 192.188 179.814 126.197 1.00 25.19 ? 483 TYR A CD1 1 
ATOM 3772 C CD2 . TYR A 1 499 ? 192.839 180.735 124.100 1.00 25.19 ? 483 TYR A CD2 1 
ATOM 3773 C CE1 . TYR A 1 499 ? 193.106 178.792 126.039 1.00 25.19 ? 483 TYR A CE1 1 
ATOM 3774 C CE2 . TYR A 1 499 ? 193.760 179.717 123.933 1.00 25.19 ? 483 TYR A CE2 1 
ATOM 3775 C CZ  . TYR A 1 499 ? 193.888 178.748 124.905 1.00 25.19 ? 483 TYR A CZ  1 
ATOM 3776 O OH  . TYR A 1 499 ? 194.802 177.733 124.744 1.00 25.19 ? 483 TYR A OH  1 
ATOM 3777 N N   . LYS A 1 500 ? 193.865 183.331 125.635 1.00 21.24 ? 484 LYS A N   1 
ATOM 3778 C CA  . LYS A 1 500 ? 195.047 183.971 125.058 1.00 21.24 ? 484 LYS A CA  1 
ATOM 3779 C C   . LYS A 1 500 ? 195.108 183.661 123.564 1.00 21.24 ? 484 LYS A C   1 
ATOM 3780 O O   . LYS A 1 500 ? 195.850 182.791 123.101 1.00 21.24 ? 484 LYS A O   1 
ATOM 3781 C CB  . LYS A 1 500 ? 196.309 183.514 125.778 1.00 21.24 ? 484 LYS A CB  1 
ATOM 3782 C CG  . LYS A 1 500 ? 196.346 183.869 127.256 1.00 21.24 ? 484 LYS A CG  1 
ATOM 3783 C CD  . LYS A 1 500 ? 196.273 185.374 127.469 1.00 21.24 ? 484 LYS A CD  1 
ATOM 3784 C CE  . LYS A 1 500 ? 197.446 186.087 126.812 1.00 21.24 ? 484 LYS A CE  1 
ATOM 3785 N NZ  . LYS A 1 500 ? 198.754 185.525 127.248 1.00 21.24 ? 484 LYS A NZ  1 
ATOM 3786 N N   . LYS A 1 501 ? 194.303 184.401 122.801 1.00 22.17 ? 485 LYS A N   1 
ATOM 3787 C CA  . LYS A 1 501 ? 194.309 184.362 121.337 1.00 22.17 ? 485 LYS A CA  1 
ATOM 3788 C C   . LYS A 1 501 ? 194.048 182.945 120.817 1.00 22.17 ? 485 LYS A C   1 
ATOM 3789 O O   . LYS A 1 501 ? 194.886 182.317 120.169 1.00 22.17 ? 485 LYS A O   1 
ATOM 3790 C CB  . LYS A 1 501 ? 195.626 184.919 120.788 1.00 22.17 ? 485 LYS A CB  1 
ATOM 3791 C CG  . LYS A 1 501 ? 196.012 186.279 121.350 1.00 22.17 ? 485 LYS A CG  1 
ATOM 3792 C CD  . LYS A 1 501 ? 194.871 187.276 121.220 1.00 22.17 ? 485 LYS A CD  1 
ATOM 3793 C CE  . LYS A 1 501 ? 195.289 188.659 121.690 1.00 22.17 ? 485 LYS A CE  1 
ATOM 3794 N NZ  . LYS A 1 501 ? 194.121 189.572 121.829 1.00 22.17 ? 485 LYS A NZ  1 
ATOM 3795 N N   . GLY A 1 502 ? 192.849 182.458 121.124 1.00 24.30 ? 486 GLY A N   1 
ATOM 3796 C CA  . GLY A 1 502 ? 192.446 181.139 120.681 1.00 24.30 ? 486 GLY A CA  1 
ATOM 3797 C C   . GLY A 1 502 ? 190.961 180.878 120.824 1.00 24.30 ? 486 GLY A C   1 
ATOM 3798 O O   . GLY A 1 502 ? 190.143 181.786 120.647 1.00 24.30 ? 486 GLY A O   1 
ATOM 3799 N N   . ASP A 1 503 ? 190.603 179.639 121.144 1.00 19.62 ? 487 ASP A N   1 
ATOM 3800 C CA  . ASP A 1 503 ? 189.212 179.233 121.281 1.00 19.62 ? 487 ASP A CA  1 
ATOM 3801 C C   . ASP A 1 503 ? 188.841 179.115 122.754 1.00 19.62 ? 487 ASP A C   1 
ATOM 3802 O O   . ASP A 1 503 ? 189.653 178.682 123.577 1.00 19.62 ? 487 ASP A O   1 
ATOM 3803 C CB  . ASP A 1 503 ? 188.963 177.900 120.572 1.00 19.62 ? 487 ASP A CB  1 
ATOM 3804 C CG  . ASP A 1 503 ? 189.280 177.961 119.091 1.00 19.62 ? 487 ASP A CG  1 
ATOM 3805 O OD1 . ASP A 1 503 ? 189.439 179.081 118.562 1.00 19.62 ? 487 ASP A OD1 1 
ATOM 3806 O OD2 . ASP A 1 503 ? 189.371 176.889 118.457 1.00 19.62 ? 487 ASP A OD2 1 
ATOM 3807 N N   . ALA A 1 504 ? 187.611 179.510 123.078 1.00 14.94 ? 488 ALA A N   1 
ATOM 3808 C CA  . ALA A 1 504 ? 187.129 179.409 124.449 1.00 14.94 ? 488 ALA A CA  1 
ATOM 3809 C C   . ALA A 1 504 ? 187.106 177.954 124.898 1.00 14.94 ? 488 ALA A C   1 
ATOM 3810 O O   . ALA A 1 504 ? 186.680 177.063 124.158 1.00 14.94 ? 488 ALA A O   1 
ATOM 3811 C CB  . ALA A 1 504 ? 185.733 180.021 124.569 1.00 14.94 ? 488 ALA A CB  1 
ATOM 3812 N N   . ASN A 1 505 ? 187.568 177.716 126.123 1.00 10.03 ? 489 ASN A N   1 
ATOM 3813 C CA  . ASN A 1 505 ? 187.685 176.357 126.653 1.00 10.03 ? 489 ASN A CA  1 
ATOM 3814 C C   . ASN A 1 505 ? 186.365 175.942 127.305 1.00 10.03 ? 489 ASN A C   1 
ATOM 3815 O O   . ASN A 1 505 ? 186.253 175.753 128.517 1.00 10.03 ? 489 ASN A O   1 
ATOM 3816 C CB  . ASN A 1 505 ? 188.850 176.270 127.629 1.00 10.03 ? 489 ASN A CB  1 
ATOM 3817 C CG  . ASN A 1 505 ? 190.159 176.717 127.012 1.00 10.03 ? 489 ASN A CG  1 
ATOM 3818 O OD1 . ASN A 1 505 ? 190.259 176.890 125.797 1.00 10.03 ? 489 ASN A OD1 1 
ATOM 3819 N ND2 . ASN A 1 505 ? 191.173 176.906 127.847 1.00 10.03 ? 489 ASN A ND2 1 
ATOM 3820 N N   . THR A 1 506 ? 185.349 175.789 126.457 1.00 6.08  ? 490 THR A N   1 
ATOM 3821 C CA  . THR A 1 506 ? 184.038 175.357 126.921 1.00 6.08  ? 490 THR A CA  1 
ATOM 3822 C C   . THR A 1 506 ? 184.056 173.867 127.229 1.00 6.08  ? 490 THR A C   1 
ATOM 3823 O O   . THR A 1 506 ? 183.511 173.060 126.469 1.00 6.08  ? 490 THR A O   1 
ATOM 3824 C CB  . THR A 1 506 ? 182.963 175.674 125.881 1.00 6.08  ? 490 THR A CB  1 
ATOM 3825 O OG1 . THR A 1 506 ? 182.840 174.578 124.967 1.00 6.08  ? 490 THR A OG1 1 
ATOM 3826 C CG2 . THR A 1 506 ? 183.328 176.932 125.110 1.00 6.08  ? 490 THR A CG2 1 
ATOM 3827 N N   . TYR A 1 507 ? 184.679 173.497 128.343 1.00 4.53  ? 491 TYR A N   1 
ATOM 3828 C CA  . TYR A 1 507 ? 184.845 172.096 128.689 1.00 4.53  ? 491 TYR A CA  1 
ATOM 3829 C C   . TYR A 1 507 ? 183.508 171.460 129.063 1.00 4.53  ? 491 TYR A C   1 
ATOM 3830 O O   . TYR A 1 507 ? 182.515 172.140 129.332 1.00 4.53  ? 491 TYR A O   1 
ATOM 3831 C CB  . TYR A 1 507 ? 185.837 171.949 129.841 1.00 4.53  ? 491 TYR A CB  1 
ATOM 3832 C CG  . TYR A 1 507 ? 187.251 172.361 129.495 1.00 4.53  ? 491 TYR A CG  1 
ATOM 3833 C CD1 . TYR A 1 507 ? 187.694 172.360 128.180 1.00 4.53  ? 491 TYR A CD1 1 
ATOM 3834 C CD2 . TYR A 1 507 ? 188.145 172.746 130.485 1.00 4.53  ? 491 TYR A CD2 1 
ATOM 3835 C CE1 . TYR A 1 507 ? 188.985 172.732 127.860 1.00 4.53  ? 491 TYR A CE1 1 
ATOM 3836 C CE2 . TYR A 1 507 ? 189.439 173.121 130.174 1.00 4.53  ? 491 TYR A CE2 1 
ATOM 3837 C CZ  . TYR A 1 507 ? 189.852 173.112 128.860 1.00 4.53  ? 491 TYR A CZ  1 
ATOM 3838 O OH  . TYR A 1 507 ? 191.138 173.483 128.542 1.00 4.53  ? 491 TYR A OH  1 
ATOM 3839 N N   . LYS A 1 508 ? 183.497 170.131 129.075 1.00 2.88  ? 492 LYS A N   1 
ATOM 3840 C CA  . LYS A 1 508 ? 182.313 169.324 129.355 1.00 2.88  ? 492 LYS A CA  1 
ATOM 3841 C C   . LYS A 1 508 ? 182.621 168.293 130.431 1.00 2.88  ? 492 LYS A C   1 
ATOM 3842 O O   . LYS A 1 508 ? 182.390 167.094 130.262 1.00 2.88  ? 492 LYS A O   1 
ATOM 3843 C CB  . LYS A 1 508 ? 181.797 168.642 128.092 1.00 2.88  ? 492 LYS A CB  1 
ATOM 3844 C CG  . LYS A 1 508 ? 180.357 168.160 128.194 1.00 2.88  ? 492 LYS A CG  1 
ATOM 3845 C CD  . LYS A 1 508 ? 180.239 166.689 127.841 1.00 2.88  ? 492 LYS A CD  1 
ATOM 3846 C CE  . LYS A 1 508 ? 178.940 166.104 128.365 1.00 2.88  ? 492 LYS A CE  1 
ATOM 3847 N NZ  . LYS A 1 508 ? 178.902 164.624 128.226 1.00 2.88  ? 492 LYS A NZ  1 
ATOM 3848 N N   . LEU A 1 509 ? 183.186 168.754 131.546 1.00 1.80  ? 493 LEU A N   1 
ATOM 3849 C CA  . LEU A 1 509 ? 183.632 167.866 132.614 1.00 1.80  ? 493 LEU A CA  1 
ATOM 3850 C C   . LEU A 1 509 ? 182.541 166.884 133.012 1.00 1.80  ? 493 LEU A C   1 
ATOM 3851 O O   . LEU A 1 509 ? 181.404 167.278 133.289 1.00 1.80  ? 493 LEU A O   1 
ATOM 3852 C CB  . LEU A 1 509 ? 184.071 168.694 133.826 1.00 1.80  ? 493 LEU A CB  1 
ATOM 3853 C CG  . LEU A 1 509 ? 184.232 167.985 135.174 1.00 1.80  ? 493 LEU A CG  1 
ATOM 3854 C CD1 . LEU A 1 509 ? 185.411 168.569 135.917 1.00 1.80  ? 493 LEU A CD1 1 
ATOM 3855 C CD2 . LEU A 1 509 ? 182.986 168.099 136.032 1.00 1.80  ? 493 LEU A CD2 1 
ATOM 3856 N N   . ASP A 1 510 ? 182.895 165.598 133.033 1.00 2.09  ? 494 ASP A N   1 
ATOM 3857 C CA  . ASP A 1 510 ? 181.971 164.547 133.436 1.00 2.09  ? 494 ASP A CA  1 
ATOM 3858 C C   . ASP A 1 510 ? 182.221 164.225 134.902 1.00 2.09  ? 494 ASP A C   1 
ATOM 3859 O O   . ASP A 1 510 ? 183.288 163.686 135.231 1.00 2.09  ? 494 ASP A O   1 
ATOM 3860 C CB  . ASP A 1 510 ? 182.166 163.307 132.576 1.00 2.09  ? 494 ASP A CB  1 
ATOM 3861 C CG  . ASP A 1 510 ? 181.177 162.207 132.902 1.00 2.09  ? 494 ASP A CG  1 
ATOM 3862 O OD1 . ASP A 1 510 ? 180.124 162.508 133.502 1.00 2.09  ? 494 ASP A OD1 1 
ATOM 3863 O OD2 . ASP A 1 510 ? 181.453 161.038 132.559 1.00 2.09  ? 494 ASP A OD2 1 
ATOM 3864 N N   . PRO A 1 511 ? 181.290 164.530 135.809 1.00 1.93  ? 495 PRO A N   1 
ATOM 3865 C CA  . PRO A 1 511 ? 181.569 164.323 137.239 1.00 1.93  ? 495 PRO A CA  1 
ATOM 3866 C C   . PRO A 1 511 ? 181.814 162.873 137.617 1.00 1.93  ? 495 PRO A C   1 
ATOM 3867 O O   . PRO A 1 511 ? 182.570 162.611 138.561 1.00 1.93  ? 495 PRO A O   1 
ATOM 3868 C CB  . PRO A 1 511 ? 180.315 164.885 137.919 1.00 1.93  ? 495 PRO A CB  1 
ATOM 3869 C CG  . PRO A 1 511 ? 179.244 164.763 136.891 1.00 1.93  ? 495 PRO A CG  1 
ATOM 3870 C CD  . PRO A 1 511 ? 179.915 164.998 135.572 1.00 1.93  ? 495 PRO A CD  1 
ATOM 3871 N N   . ALA A 1 512 ? 181.195 161.921 136.915 1.00 2.81  ? 496 ALA A N   1 
ATOM 3872 C CA  . ALA A 1 512 ? 181.348 160.515 137.279 1.00 2.81  ? 496 ALA A CA  1 
ATOM 3873 C C   . ALA A 1 512 ? 182.778 160.032 137.069 1.00 2.81  ? 496 ALA A C   1 
ATOM 3874 O O   . ALA A 1 512 ? 183.319 159.298 137.904 1.00 2.81  ? 496 ALA A O   1 
ATOM 3875 C CB  . ALA A 1 512 ? 180.370 159.656 136.479 1.00 2.81  ? 496 ALA A CB  1 
ATOM 3876 N N   . THR A 1 513 ? 183.406 160.432 135.964 1.00 3.33  ? 497 THR A N   1 
ATOM 3877 C CA  . THR A 1 513 ? 184.750 159.985 135.628 1.00 3.33  ? 497 THR A CA  1 
ATOM 3878 C C   . THR A 1 513 ? 185.808 161.064 135.813 1.00 3.33  ? 497 THR A C   1 
ATOM 3879 O O   . THR A 1 513 ? 187.002 160.753 135.741 1.00 3.33  ? 497 THR A O   1 
ATOM 3880 C CB  . THR A 1 513 ? 184.788 159.480 134.176 1.00 3.33  ? 497 THR A CB  1 
ATOM 3881 O OG1 . THR A 1 513 ? 183.538 158.860 133.855 1.00 3.33  ? 497 THR A OG1 1 
ATOM 3882 C CG2 . THR A 1 513 ? 185.900 158.458 133.990 1.00 3.33  ? 497 THR A CG2 1 
ATOM 3883 N N   . SER A 1 514 ? 185.404 162.310 136.067 1.00 3.21  ? 498 SER A N   1 
ATOM 3884 C CA  . SER A 1 514 ? 186.324 163.445 136.190 1.00 3.21  ? 498 SER A CA  1 
ATOM 3885 C C   . SER A 1 514 ? 187.196 163.587 134.946 1.00 3.21  ? 498 SER A C   1 
ATOM 3886 O O   . SER A 1 514 ? 188.369 163.954 135.025 1.00 3.21  ? 498 SER A O   1 
ATOM 3887 C CB  . SER A 1 514 ? 187.190 163.338 137.446 1.00 3.21  ? 498 SER A CB  1 
ATOM 3888 O OG  . SER A 1 514 ? 187.945 162.140 137.455 1.00 3.21  ? 498 SER A OG  1 
ATOM 3889 N N   . ALA A 1 515 ? 186.616 163.295 133.787 1.00 4.52  ? 499 ALA A N   1 
ATOM 3890 C CA  . ALA A 1 515 ? 187.296 163.430 132.508 1.00 4.52  ? 499 ALA A CA  1 
ATOM 3891 C C   . ALA A 1 515 ? 186.830 164.712 131.838 1.00 4.52  ? 499 ALA A C   1 
ATOM 3892 O O   . ALA A 1 515 ? 185.628 164.904 131.625 1.00 4.52  ? 499 ALA A O   1 
ATOM 3893 C CB  . ALA A 1 515 ? 187.022 162.225 131.607 1.00 4.52  ? 499 ALA A CB  1 
ATOM 3894 N N   . VAL A 1 516 ? 187.777 165.582 131.503 1.00 5.50  ? 500 VAL A N   1 
ATOM 3895 C CA  . VAL A 1 516 ? 187.485 166.877 130.902 1.00 5.50  ? 500 VAL A CA  1 
ATOM 3896 C C   . VAL A 1 516 ? 187.695 166.751 129.397 1.00 5.50  ? 500 VAL A C   1 
ATOM 3897 O O   . VAL A 1 516 ? 188.702 166.193 128.942 1.00 5.50  ? 500 VAL A O   1 
ATOM 3898 C CB  . VAL A 1 516 ? 188.334 167.998 131.531 1.00 5.50  ? 500 VAL A CB  1 
ATOM 3899 C CG1 . VAL A 1 516 ? 189.714 168.112 130.893 1.00 5.50  ? 500 VAL A CG1 1 
ATOM 3900 C CG2 . VAL A 1 516 ? 187.597 169.320 131.461 1.00 5.50  ? 500 VAL A CG2 1 
ATOM 3901 N N   . THR A 1 517 ? 186.705 167.193 128.628 1.00 6.88  ? 501 THR A N   1 
ATOM 3902 C CA  . THR A 1 517 ? 186.733 167.104 127.175 1.00 6.88  ? 501 THR A CA  1 
ATOM 3903 C C   . THR A 1 517 ? 186.395 168.458 126.569 1.00 6.88  ? 501 THR A C   1 
ATOM 3904 O O   . THR A 1 517 ? 185.413 169.096 126.961 1.00 6.88  ? 501 THR A O   1 
ATOM 3905 C CB  . THR A 1 517 ? 185.747 166.049 126.660 1.00 6.88  ? 501 THR A CB  1 
ATOM 3906 O OG1 . THR A 1 517 ? 184.419 166.391 127.075 1.00 6.88  ? 501 THR A OG1 1 
ATOM 3907 C CG2 . THR A 1 517 ? 186.102 164.672 127.198 1.00 6.88  ? 501 THR A CG2 1 
ATOM 3908 N N   . VAL A 1 518 ? 187.206 168.890 125.609 1.00 6.97  ? 502 VAL A N   1 
ATOM 3909 C CA  . VAL A 1 518 ? 186.969 170.154 124.921 1.00 6.97  ? 502 VAL A CA  1 
ATOM 3910 C C   . VAL A 1 518 ? 185.861 169.948 123.897 1.00 6.97  ? 502 VAL A C   1 
ATOM 3911 O O   . VAL A 1 518 ? 185.968 169.089 123.016 1.00 6.97  ? 502 VAL A O   1 
ATOM 3912 C CB  . VAL A 1 518 ? 188.250 170.670 124.253 1.00 6.97  ? 502 VAL A CB  1 
ATOM 3913 C CG1 . VAL A 1 518 ? 188.120 172.150 123.930 1.00 6.97  ? 502 VAL A CG1 1 
ATOM 3914 C CG2 . VAL A 1 518 ? 189.451 170.417 125.149 1.00 6.97  ? 502 VAL A CG2 1 
ATOM 3915 N N   . THR A 1 519 ? 184.796 170.737 124.010 1.00 10.87 ? 503 THR A N   1 
ATOM 3916 C CA  . THR A 1 519 ? 183.648 170.655 123.113 1.00 10.87 ? 503 THR A CA  1 
ATOM 3917 C C   . THR A 1 519 ? 183.443 172.019 122.467 1.00 10.87 ? 503 THR A C   1 
ATOM 3918 O O   . THR A 1 519 ? 183.140 172.998 123.156 1.00 10.87 ? 503 THR A O   1 
ATOM 3919 C CB  . THR A 1 519 ? 182.392 170.211 123.861 1.00 10.87 ? 503 THR A CB  1 
ATOM 3920 O OG1 . THR A 1 519 ? 182.530 168.841 124.258 1.00 10.87 ? 503 THR A OG1 1 
ATOM 3921 C CG2 . THR A 1 519 ? 181.167 170.354 122.973 1.00 10.87 ? 503 THR A CG2 1 
ATOM 3922 N N   . ARG A 1 520 ? 183.611 172.079 121.150 1.00 20.95 ? 504 ARG A N   1 
ATOM 3923 C CA  . ARG A 1 520 ? 183.437 173.306 120.393 1.00 20.95 ? 504 ARG A CA  1 
ATOM 3924 C C   . ARG A 1 520 ? 182.057 173.324 119.739 1.00 20.95 ? 504 ARG A C   1 
ATOM 3925 O O   . ARG A 1 520 ? 181.221 172.443 119.956 1.00 20.95 ? 504 ARG A O   1 
ATOM 3926 C CB  . ARG A 1 520 ? 184.549 173.452 119.352 1.00 20.95 ? 504 ARG A CB  1 
ATOM 3927 C CG  . ARG A 1 520 ? 185.939 173.591 119.953 1.00 20.95 ? 504 ARG A CG  1 
ATOM 3928 C CD  . ARG A 1 520 ? 186.534 174.964 119.683 1.00 20.95 ? 504 ARG A CD  1 
ATOM 3929 N NE  . ARG A 1 520 ? 186.879 175.148 118.278 1.00 20.95 ? 504 ARG A NE  1 
ATOM 3930 C CZ  . ARG A 1 520 ? 186.170 175.866 117.418 1.00 20.95 ? 504 ARG A CZ  1 
ATOM 3931 N NH1 . ARG A 1 520 ? 185.063 176.489 117.786 1.00 20.95 ? 504 ARG A NH1 1 
ATOM 3932 N NH2 . ARG A 1 520 ? 186.583 175.963 116.157 1.00 20.95 ? 504 ARG A NH2 1 
ATOM 3933 N N   . GLY A 1 521 ? 181.820 174.348 118.924 1.00 18.26 ? 505 GLY A N   1 
ATOM 3934 C CA  . GLY A 1 521 ? 180.537 174.522 118.275 1.00 18.26 ? 505 GLY A CA  1 
ATOM 3935 C C   . GLY A 1 521 ? 179.980 175.914 118.483 1.00 18.26 ? 505 GLY A C   1 
ATOM 3936 O O   . GLY A 1 521 ? 179.007 176.310 117.834 1.00 18.26 ? 505 GLY A O   1 
ATOM 3937 N N   . ILE A 1 522 ? 180.595 176.665 119.388 1.00 17.16 ? 506 ILE A N   1 
ATOM 3938 C CA  . ILE A 1 522 ? 180.206 178.039 119.679 1.00 17.16 ? 506 ILE A CA  1 
ATOM 3939 C C   . ILE A 1 522 ? 181.218 178.958 119.005 1.00 17.16 ? 506 ILE A C   1 
ATOM 3940 O O   . ILE A 1 522 ? 182.429 178.827 119.211 1.00 17.16 ? 506 ILE A O   1 
ATOM 3941 C CB  . ILE A 1 522 ? 180.123 178.297 121.190 1.00 17.16 ? 506 ILE A CB  1 
ATOM 3942 C CG1 . ILE A 1 522 ? 179.946 179.791 121.469 1.00 17.16 ? 506 ILE A CG1 1 
ATOM 3943 C CG2 . ILE A 1 522 ? 181.344 177.737 121.909 1.00 17.16 ? 506 ILE A CG2 1 
ATOM 3944 C CD1 . ILE A 1 522 ? 179.774 180.120 122.934 1.00 17.16 ? 506 ILE A CD1 1 
ATOM 3945 N N   . LYS A 1 523 ? 180.725 179.881 118.186 1.00 19.31 ? 507 LYS A N   1 
ATOM 3946 C CA  . LYS A 1 523 ? 181.564 180.844 117.477 1.00 19.31 ? 507 LYS A CA  1 
ATOM 3947 C C   . LYS A 1 523 ? 181.029 182.240 117.786 1.00 19.31 ? 507 LYS A C   1 
ATOM 3948 O O   . LYS A 1 523 ? 180.183 182.772 117.066 1.00 19.31 ? 507 LYS A O   1 
ATOM 3949 C CB  . LYS A 1 523 ? 181.578 180.561 115.977 1.00 19.31 ? 507 LYS A CB  1 
ATOM 3950 C CG  . LYS A 1 523 ? 182.743 181.200 115.237 1.00 19.31 ? 507 LYS A CG  1 
ATOM 3951 C CD  . LYS A 1 523 ? 184.079 180.691 115.757 1.00 19.31 ? 507 LYS A CD  1 
ATOM 3952 C CE  . LYS A 1 523 ? 184.201 179.182 115.599 1.00 19.31 ? 507 LYS A CE  1 
ATOM 3953 N NZ  . LYS A 1 523 ? 184.002 178.754 114.188 1.00 19.31 ? 507 LYS A NZ  1 
ATOM 3954 N N   . VAL A 1 524 ? 181.533 182.831 118.869 1.00 21.18 ? 508 VAL A N   1 
ATOM 3955 C CA  . VAL A 1 524 ? 181.126 184.157 119.308 1.00 21.18 ? 508 VAL A CA  1 
ATOM 3956 C C   . VAL A 1 524 ? 182.373 185.012 119.493 1.00 21.18 ? 508 VAL A C   1 
ATOM 3957 O O   . VAL A 1 524 ? 183.475 184.509 119.713 1.00 21.18 ? 508 VAL A O   1 
ATOM 3958 C CB  . VAL A 1 524 ? 180.299 184.116 120.609 1.00 21.18 ? 508 VAL A CB  1 
ATOM 3959 C CG1 . VAL A 1 524 ? 178.990 183.378 120.383 1.00 21.18 ? 508 VAL A CG1 1 
ATOM 3960 C CG2 . VAL A 1 524 ? 181.099 183.462 121.725 1.00 21.18 ? 508 VAL A CG2 1 
ATOM 3961 N N   . LEU A 1 525 ? 182.181 186.327 119.400 1.00 19.56 ? 509 LEU A N   1 
ATOM 3962 C CA  . LEU A 1 525 ? 183.264 187.289 119.546 1.00 19.56 ? 509 LEU A CA  1 
ATOM 3963 C C   . LEU A 1 525 ? 183.292 187.933 120.926 1.00 19.56 ? 509 LEU A C   1 
ATOM 3964 O O   . LEU A 1 525 ? 184.137 188.799 121.178 1.00 19.56 ? 509 LEU A O   1 
ATOM 3965 C CB  . LEU A 1 525 ? 183.161 188.368 118.466 1.00 19.56 ? 509 LEU A CB  1 
ATOM 3966 C CG  . LEU A 1 525 ? 183.259 187.892 117.015 1.00 19.56 ? 509 LEU A CG  1 
ATOM 3967 C CD1 . LEU A 1 525 ? 183.254 189.077 116.061 1.00 19.56 ? 509 LEU A CD1 1 
ATOM 3968 C CD2 . LEU A 1 525 ? 184.501 187.039 116.811 1.00 19.56 ? 509 LEU A CD2 1 
ATOM 3969 N N   . LEU A 1 526 ? 182.392 187.536 121.823 1.00 16.38 ? 510 LEU A N   1 
ATOM 3970 C CA  . LEU A 1 526 ? 182.348 188.096 123.167 1.00 16.38 ? 510 LEU A CA  1 
ATOM 3971 C C   . LEU A 1 526 ? 183.227 187.345 124.158 1.00 16.38 ? 510 LEU A C   1 
ATOM 3972 O O   . LEU A 1 526 ? 183.434 187.838 125.272 1.00 16.38 ? 510 LEU A O   1 
ATOM 3973 C CB  . LEU A 1 526 ? 180.903 188.122 123.679 1.00 16.38 ? 510 LEU A CB  1 
ATOM 3974 C CG  . LEU A 1 526 ? 180.152 186.790 123.703 1.00 16.38 ? 510 LEU A CG  1 
ATOM 3975 C CD1 . LEU A 1 526 ? 180.252 186.145 125.069 1.00 16.38 ? 510 LEU A CD1 1 
ATOM 3976 C CD2 . LEU A 1 526 ? 178.699 186.989 123.313 1.00 16.38 ? 510 LEU A CD2 1 
ATOM 3977 N N   . THR A 1 527 ? 183.747 186.174 123.785 1.00 17.03 ? 511 THR A N   1 
ATOM 3978 C CA  . THR A 1 527 ? 184.583 185.396 124.691 1.00 17.03 ? 511 THR A CA  1 
ATOM 3979 C C   . THR A 1 527 ? 185.929 186.054 124.963 1.00 17.03 ? 511 THR A C   1 
ATOM 3980 O O   . THR A 1 527 ? 186.639 185.612 125.872 1.00 17.03 ? 511 THR A O   1 
ATOM 3981 C CB  . THR A 1 527 ? 184.807 183.990 124.131 1.00 17.03 ? 511 THR A CB  1 
ATOM 3982 O OG1 . THR A 1 527 ? 185.744 183.289 124.958 1.00 17.03 ? 511 THR A OG1 1 
ATOM 3983 C CG2 . THR A 1 527 ? 185.348 184.063 122.711 1.00 17.03 ? 511 THR A CG2 1 
ATOM 3984 N N   . ASN A 1 528 ? 186.293 187.086 124.206 1.00 18.20 ? 512 ASN A N   1 
ATOM 3985 C CA  . ASN A 1 528 ? 187.553 187.791 124.399 1.00 18.20 ? 512 ASN A CA  1 
ATOM 3986 C C   . ASN A 1 528 ? 187.576 188.639 125.664 1.00 18.20 ? 512 ASN A C   1 
ATOM 3987 O O   . ASN A 1 528 ? 188.641 189.152 126.023 1.00 18.20 ? 512 ASN A O   1 
ATOM 3988 C CB  . ASN A 1 528 ? 187.850 188.675 123.185 1.00 18.20 ? 512 ASN A CB  1 
ATOM 3989 C CG  . ASN A 1 528 ? 186.988 189.921 123.148 1.00 18.20 ? 512 ASN A CG  1 
ATOM 3990 O OD1 . ASN A 1 528 ? 187.465 191.028 123.398 1.00 18.20 ? 512 ASN A OD1 1 
ATOM 3991 N ND2 . ASN A 1 528 ? 185.709 189.747 122.835 1.00 18.20 ? 512 ASN A ND2 1 
ATOM 3992 N N   . LEU A 1 529 ? 186.440 188.807 126.337 1.00 17.29 ? 513 LEU A N   1 
ATOM 3993 C CA  . LEU A 1 529 ? 186.368 189.612 127.547 1.00 17.29 ? 513 LEU A CA  1 
ATOM 3994 C C   . LEU A 1 529 ? 185.445 188.933 128.548 1.00 17.29 ? 513 LEU A C   1 
ATOM 3995 O O   . LEU A 1 529 ? 184.616 188.093 128.190 1.00 17.29 ? 513 LEU A O   1 
ATOM 3996 C CB  . LEU A 1 529 ? 185.887 191.037 127.245 1.00 17.29 ? 513 LEU A CB  1 
ATOM 3997 C CG  . LEU A 1 529 ? 186.941 191.954 126.619 1.00 17.29 ? 513 LEU A CG  1 
ATOM 3998 C CD1 . LEU A 1 529 ? 186.295 193.150 125.942 1.00 17.29 ? 513 LEU A CD1 1 
ATOM 3999 C CD2 . LEU A 1 529 ? 187.948 192.406 127.666 1.00 17.29 ? 513 LEU A CD2 1 
ATOM 4000 N N   . GLN A 1 530 ? 185.603 189.309 129.816 1.00 12.01 ? 514 GLN A N   1 
ATOM 4001 C CA  . GLN A 1 530 ? 184.837 188.706 130.895 1.00 12.01 ? 514 GLN A CA  1 
ATOM 4002 C C   . GLN A 1 530 ? 183.348 189.009 130.732 1.00 12.01 ? 514 GLN A C   1 
ATOM 4003 O O   . GLN A 1 530 ? 182.940 189.871 129.948 1.00 12.01 ? 514 GLN A O   1 
ATOM 4004 C CB  . GLN A 1 530 ? 185.337 189.207 132.248 1.00 12.01 ? 514 GLN A CB  1 
ATOM 4005 C CG  . GLN A 1 530 ? 185.443 190.719 132.347 1.00 12.01 ? 514 GLN A CG  1 
ATOM 4006 C CD  . GLN A 1 530 ? 185.864 191.183 133.727 1.00 12.01 ? 514 GLN A CD  1 
ATOM 4007 O OE1 . GLN A 1 530 ? 185.933 190.392 134.667 1.00 12.01 ? 514 GLN A OE1 1 
ATOM 4008 N NE2 . GLN A 1 530 ? 186.148 192.474 133.855 1.00 12.01 ? 514 GLN A NE2 1 
ATOM 4009 N N   . PHE A 1 531 ? 182.530 188.289 131.489 1.00 6.50  ? 515 PHE A N   1 
ATOM 4010 C CA  . PHE A 1 531 ? 181.078 188.388 131.363 1.00 6.50  ? 515 PHE A CA  1 
ATOM 4011 C C   . PHE A 1 531 ? 180.441 187.799 132.618 1.00 6.50  ? 515 PHE A C   1 
ATOM 4012 O O   . PHE A 1 531 ? 181.134 187.418 133.569 1.00 6.50  ? 515 PHE A O   1 
ATOM 4013 C CB  . PHE A 1 531 ? 180.593 187.683 130.096 1.00 6.50  ? 515 PHE A CB  1 
ATOM 4014 C CG  . PHE A 1 531 ? 181.282 186.374 129.823 1.00 6.50  ? 515 PHE A CG  1 
ATOM 4015 C CD1 . PHE A 1 531 ? 180.999 185.253 130.584 1.00 6.50  ? 515 PHE A CD1 1 
ATOM 4016 C CD2 . PHE A 1 531 ? 182.202 186.263 128.797 1.00 6.50  ? 515 PHE A CD2 1 
ATOM 4017 C CE1 . PHE A 1 531 ? 181.626 184.049 130.330 1.00 6.50  ? 515 PHE A CE1 1 
ATOM 4018 C CE2 . PHE A 1 531 ? 182.831 185.062 128.540 1.00 6.50  ? 515 PHE A CE2 1 
ATOM 4019 C CZ  . PHE A 1 531 ? 182.542 183.954 129.308 1.00 6.50  ? 515 PHE A CZ  1 
ATOM 4020 N N   . VAL A 1 532 ? 179.109 187.728 132.616 1.00 2.09  ? 516 VAL A N   1 
ATOM 4021 C CA  . VAL A 1 532 ? 178.344 187.059 133.663 1.00 2.09  ? 516 VAL A CA  1 
ATOM 4022 C C   . VAL A 1 532 ? 177.709 185.831 133.023 1.00 2.09  ? 516 VAL A C   1 
ATOM 4023 O O   . VAL A 1 532 ? 177.764 185.664 131.800 1.00 2.09  ? 516 VAL A O   1 
ATOM 4024 C CB  . VAL A 1 532 ? 177.286 187.995 134.279 1.00 2.09  ? 516 VAL A CB  1 
ATOM 4025 C CG1 . VAL A 1 532 ? 176.802 187.470 135.626 1.00 2.09  ? 516 VAL A CG1 1 
ATOM 4026 C CG2 . VAL A 1 532 ? 177.839 189.400 134.428 1.00 2.09  ? 516 VAL A CG2 1 
ATOM 4027 N N   . LEU A 1 533 ? 177.106 184.964 133.830 1.00 0.47  ? 517 LEU A N   1 
ATOM 4028 C CA  . LEU A 1 533 ? 176.529 183.725 133.329 1.00 0.47  ? 517 LEU A CA  1 
ATOM 4029 C C   . LEU A 1 533 ? 175.236 183.458 134.095 1.00 0.47  ? 517 LEU A C   1 
ATOM 4030 O O   . LEU A 1 533 ? 174.853 184.216 134.991 1.00 0.47  ? 517 LEU A O   1 
ATOM 4031 C CB  . LEU A 1 533 ? 177.551 182.587 133.449 1.00 0.47  ? 517 LEU A CB  1 
ATOM 4032 C CG  . LEU A 1 533 ? 177.341 181.325 132.619 1.00 0.47  ? 517 LEU A CG  1 
ATOM 4033 C CD1 . LEU A 1 533 ? 178.028 181.469 131.282 1.00 0.47  ? 517 LEU A CD1 1 
ATOM 4034 C CD2 . LEU A 1 533 ? 177.888 180.136 133.368 1.00 0.47  ? 517 LEU A CD2 1 
ATOM 4035 N N   . ALA A 1 534 ? 174.553 182.375 133.738 1.00 0.28  ? 518 ALA A N   1 
ATOM 4036 C CA  . ALA A 1 534 ? 173.292 182.023 134.376 1.00 0.28  ? 518 ALA A CA  1 
ATOM 4037 C C   . ALA A 1 534 ? 173.147 180.511 134.508 1.00 0.28  ? 518 ALA A C   1 
ATOM 4038 O O   . ALA A 1 534 ? 172.581 179.852 133.637 1.00 0.28  ? 518 ALA A O   1 
ATOM 4039 C CB  . ALA A 1 534 ? 172.128 182.602 133.594 1.00 0.28  ? 518 ALA A CB  1 
ATOM 4040 N N   . PRO B 1 23  ? 184.165 169.842 157.153 1.00 3.15  ? 7   PRO B N   1 
ATOM 4041 C CA  . PRO B 1 23  ? 184.687 168.513 156.820 1.00 3.15  ? 7   PRO B CA  1 
ATOM 4042 C C   . PRO B 1 23  ? 185.473 168.510 155.514 1.00 3.15  ? 7   PRO B C   1 
ATOM 4043 O O   . PRO B 1 23  ? 185.853 169.574 155.025 1.00 3.15  ? 7   PRO B O   1 
ATOM 4044 C CB  . PRO B 1 23  ? 183.420 167.666 156.696 1.00 3.15  ? 7   PRO B CB  1 
ATOM 4045 C CG  . PRO B 1 23  ? 182.461 168.317 157.628 1.00 3.15  ? 7   PRO B CG  1 
ATOM 4046 C CD  . PRO B 1 23  ? 182.743 169.793 157.535 1.00 3.15  ? 7   PRO B CD  1 
ATOM 4047 N N   . GLY B 1 24  ? 185.714 167.328 154.963 1.00 2.50  ? 8   GLY B N   1 
ATOM 4048 C CA  . GLY B 1 24  ? 186.441 167.238 153.713 1.00 2.50  ? 8   GLY B CA  1 
ATOM 4049 C C   . GLY B 1 24  ? 186.699 165.796 153.338 1.00 2.50  ? 8   GLY B C   1 
ATOM 4050 O O   . GLY B 1 24  ? 186.346 164.868 154.069 1.00 2.50  ? 8   GLY B O   1 
ATOM 4051 N N   . ALA B 1 25  ? 187.327 165.626 152.175 1.00 3.29  ? 9   ALA B N   1 
ATOM 4052 C CA  . ALA B 1 25  ? 187.694 164.308 151.674 1.00 3.29  ? 9   ALA B CA  1 
ATOM 4053 C C   . ALA B 1 25  ? 188.741 164.432 150.576 1.00 3.29  ? 9   ALA B C   1 
ATOM 4054 O O   . ALA B 1 25  ? 189.264 165.523 150.327 1.00 3.29  ? 9   ALA B O   1 
ATOM 4055 C CB  . ALA B 1 25  ? 186.463 163.562 151.156 1.00 3.29  ? 9   ALA B CB  1 
ATOM 4056 N N   . SER B 1 26  ? 189.049 163.323 149.912 1.00 5.33  ? 10  SER B N   1 
ATOM 4057 C CA  . SER B 1 26  ? 190.021 163.312 148.828 1.00 5.33  ? 10  SER B CA  1 
ATOM 4058 C C   . SER B 1 26  ? 189.421 162.527 147.675 1.00 5.33  ? 10  SER B C   1 
ATOM 4059 O O   . SER B 1 26  ? 188.366 161.903 147.815 1.00 5.33  ? 10  SER B O   1 
ATOM 4060 C CB  . SER B 1 26  ? 191.357 162.704 149.266 1.00 5.33  ? 10  SER B CB  1 
ATOM 4061 O OG  . SER B 1 26  ? 192.101 163.620 150.051 1.00 5.33  ? 10  SER B OG  1 
ATOM 4062 N N   . MET B 1 27  ? 190.104 162.563 146.532 1.00 5.50  ? 11  MET B N   1 
ATOM 4063 C CA  . MET B 1 27  ? 189.527 161.966 145.335 1.00 5.50  ? 11  MET B CA  1 
ATOM 4064 C C   . MET B 1 27  ? 189.689 160.448 145.389 1.00 5.50  ? 11  MET B C   1 
ATOM 4065 O O   . MET B 1 27  ? 190.494 159.854 144.663 1.00 5.50  ? 11  MET B O   1 
ATOM 4066 C CB  . MET B 1 27  ? 190.150 162.579 144.073 1.00 5.50  ? 11  MET B CB  1 
ATOM 4067 C CG  . MET B 1 27  ? 189.765 161.895 142.769 1.00 5.50  ? 11  MET B CG  1 
ATOM 4068 S SD  . MET B 1 27  ? 188.007 162.072 142.427 1.00 5.50  ? 11  MET B SD  1 
ATOM 4069 C CE  . MET B 1 27  ? 188.024 162.123 140.643 1.00 5.50  ? 11  MET B CE  1 
ATOM 4070 N N   . ASP B 1 28  ? 188.974 159.825 146.321 1.00 8.71  ? 12  ASP B N   1 
ATOM 4071 C CA  . ASP B 1 28  ? 188.624 158.408 146.264 1.00 8.71  ? 12  ASP B CA  1 
ATOM 4072 C C   . ASP B 1 28  ? 187.205 158.344 146.813 1.00 8.71  ? 12  ASP B C   1 
ATOM 4073 O O   . ASP B 1 28  ? 186.724 157.279 147.213 1.00 8.71  ? 12  ASP B O   1 
ATOM 4074 C CB  . ASP B 1 28  ? 189.589 157.539 147.064 1.00 8.71  ? 12  ASP B CB  1 
ATOM 4075 C CG  . ASP B 1 28  ? 189.721 156.140 146.490 1.00 8.71  ? 12  ASP B CG  1 
ATOM 4076 O OD1 . ASP B 1 28  ? 190.516 155.957 145.544 1.00 8.71  ? 12  ASP B OD1 1 
ATOM 4077 O OD2 . ASP B 1 28  ? 189.027 155.225 146.980 1.00 8.71  ? 12  ASP B OD2 1 
ATOM 4078 N N   . GLU B 1 29  ? 186.545 159.501 146.821 1.00 4.47  ? 13  GLU B N   1 
ATOM 4079 C CA  . GLU B 1 29  ? 185.191 159.646 147.334 1.00 4.47  ? 13  GLU B CA  1 
ATOM 4080 C C   . GLU B 1 29  ? 184.320 160.314 146.283 1.00 4.47  ? 13  GLU B C   1 
ATOM 4081 O O   . GLU B 1 29  ? 183.523 161.200 146.603 1.00 4.47  ? 13  GLU B O   1 
ATOM 4082 C CB  . GLU B 1 29  ? 185.185 160.465 148.626 1.00 4.47  ? 13  GLU B CB  1 
ATOM 4083 C CG  . GLU B 1 29  ? 185.983 159.851 149.760 1.00 4.47  ? 13  GLU B CG  1 
ATOM 4084 C CD  . GLU B 1 29  ? 185.226 158.755 150.478 1.00 4.47  ? 13  GLU B CD  1 
ATOM 4085 O OE1 . GLU B 1 29  ? 183.995 158.892 150.635 1.00 4.47  ? 13  GLU B OE1 1 
ATOM 4086 O OE2 . GLU B 1 29  ? 185.860 157.759 150.886 1.00 4.47  ? 13  GLU B OE2 1 
ATOM 4087 N N   . ASN B 1 30  ? 184.485 159.912 145.025 1.00 3.36  ? 14  ASN B N   1 
ATOM 4088 C CA  . ASN B 1 30  ? 183.677 160.451 143.939 1.00 3.36  ? 14  ASN B CA  1 
ATOM 4089 C C   . ASN B 1 30  ? 182.211 160.171 144.236 1.00 3.36  ? 14  ASN B C   1 
ATOM 4090 O O   . ASN B 1 30  ? 181.787 159.012 144.274 1.00 3.36  ? 14  ASN B O   1 
ATOM 4091 C CB  . ASN B 1 30  ? 184.100 159.835 142.609 1.00 3.36  ? 14  ASN B CB  1 
ATOM 4092 C CG  . ASN B 1 30  ? 183.546 160.587 141.417 1.00 3.36  ? 14  ASN B CG  1 
ATOM 4093 O OD1 . ASN B 1 30  ? 183.065 161.711 141.548 1.00 3.36  ? 14  ASN B OD1 1 
ATOM 4094 N ND2 . ASN B 1 30  ? 183.613 159.968 140.244 1.00 3.36  ? 14  ASN B ND2 1 
ATOM 4095 N N   . TYR B 1 31  ? 181.434 161.233 144.447 1.00 9.84  ? 15  TYR B N   1 
ATOM 4096 C CA  . TYR B 1 31  ? 180.065 161.094 144.927 1.00 9.84  ? 15  TYR B CA  1 
ATOM 4097 C C   . TYR B 1 31  ? 179.144 160.403 143.934 1.00 9.84  ? 15  TYR B C   1 
ATOM 4098 O O   . TYR B 1 31  ? 177.980 160.158 144.267 1.00 9.84  ? 15  TYR B O   1 
ATOM 4099 C CB  . TYR B 1 31  ? 179.516 162.471 145.296 1.00 9.84  ? 15  TYR B CB  1 
ATOM 4100 C CG  . TYR B 1 31  ? 179.522 162.722 146.781 1.00 9.84  ? 15  TYR B CG  1 
ATOM 4101 C CD1 . TYR B 1 31  ? 180.537 162.223 147.579 1.00 9.84  ? 15  TYR B CD1 1 
ATOM 4102 C CD2 . TYR B 1 31  ? 178.529 163.476 147.383 1.00 9.84  ? 15  TYR B CD2 1 
ATOM 4103 C CE1 . TYR B 1 31  ? 180.548 162.441 148.938 1.00 9.84  ? 15  TYR B CE1 1 
ATOM 4104 C CE2 . TYR B 1 31  ? 178.540 163.708 148.740 1.00 9.84  ? 15  TYR B CE2 1 
ATOM 4105 C CZ  . TYR B 1 31  ? 179.553 163.190 149.512 1.00 9.84  ? 15  TYR B CZ  1 
ATOM 4106 O OH  . TYR B 1 31  ? 179.570 163.415 150.867 1.00 9.84  ? 15  TYR B OH  1 
ATOM 4107 N N   . PHE B 1 32  ? 179.622 160.082 142.734 1.00 9.84  ? 16  PHE B N   1 
ATOM 4108 C CA  . PHE B 1 32  ? 178.811 159.320 141.796 1.00 9.84  ? 16  PHE B CA  1 
ATOM 4109 C C   . PHE B 1 32  ? 179.085 157.824 141.861 1.00 9.84  ? 16  PHE B C   1 
ATOM 4110 O O   . PHE B 1 32  ? 178.134 157.044 141.978 1.00 9.84  ? 16  PHE B O   1 
ATOM 4111 C CB  . PHE B 1 32  ? 179.013 159.847 140.374 1.00 9.84  ? 16  PHE B CB  1 
ATOM 4112 C CG  . PHE B 1 32  ? 178.383 161.190 140.142 1.00 9.84  ? 16  PHE B CG  1 
ATOM 4113 C CD1 . PHE B 1 32  ? 178.913 162.330 140.718 1.00 9.84  ? 16  PHE B CD1 1 
ATOM 4114 C CD2 . PHE B 1 32  ? 177.242 161.308 139.371 1.00 9.84  ? 16  PHE B CD2 1 
ATOM 4115 C CE1 . PHE B 1 32  ? 178.327 163.562 140.516 1.00 9.84  ? 16  PHE B CE1 1 
ATOM 4116 C CE2 . PHE B 1 32  ? 176.653 162.539 139.166 1.00 9.84  ? 16  PHE B CE2 1 
ATOM 4117 C CZ  . PHE B 1 32  ? 177.197 163.666 139.740 1.00 9.84  ? 16  PHE B CZ  1 
ATOM 4118 N N   . VAL B 1 33  ? 180.347 157.391 141.793 1.00 1.07  ? 17  VAL B N   1 
ATOM 4119 C CA  . VAL B 1 33  ? 180.652 156.006 142.144 1.00 1.07  ? 17  VAL B CA  1 
ATOM 4120 C C   . VAL B 1 33  ? 181.751 155.938 143.210 1.00 1.07  ? 17  VAL B C   1 
ATOM 4121 O O   . VAL B 1 33  ? 182.910 155.600 142.945 1.00 1.07  ? 17  VAL B O   1 
ATOM 4122 C CB  . VAL B 1 33  ? 180.969 155.189 140.863 1.00 1.07  ? 17  VAL B CB  1 
ATOM 4123 C CG1 . VAL B 1 33  ? 179.970 155.513 139.771 1.00 1.07  ? 17  VAL B CG1 1 
ATOM 4124 C CG2 . VAL B 1 33  ? 182.332 155.530 140.264 1.00 1.07  ? 17  VAL B CG2 1 
ATOM 4125 N N   . ASN B 1 34  ? 181.350 156.219 144.451 1.00 0.85  ? 18  ASN B N   1 
ATOM 4126 C CA  . ASN B 1 34  ? 182.027 155.900 145.705 1.00 0.85  ? 18  ASN B CA  1 
ATOM 4127 C C   . ASN B 1 34  ? 181.213 156.583 146.791 1.00 0.85  ? 18  ASN B C   1 
ATOM 4128 O O   . ASN B 1 34  ? 180.485 157.533 146.488 1.00 0.85  ? 18  ASN B O   1 
ATOM 4129 C CB  . ASN B 1 34  ? 183.485 156.361 145.734 1.00 0.85  ? 18  ASN B CB  1 
ATOM 4130 C CG  . ASN B 1 34  ? 184.459 155.213 145.539 1.00 0.85  ? 18  ASN B CG  1 
ATOM 4131 O OD1 . ASN B 1 34  ? 184.940 154.620 146.504 1.00 0.85  ? 18  ASN B OD1 1 
ATOM 4132 N ND2 . ASN B 1 34  ? 184.758 154.899 144.285 1.00 0.85  ? 18  ASN B ND2 1 
ATOM 4133 N N   . TYR B 1 35  ? 181.333 156.158 148.046 1.00 1.77  ? 19  TYR B N   1 
ATOM 4134 C CA  . TYR B 1 35  ? 180.578 156.852 149.082 1.00 1.77  ? 19  TYR B CA  1 
ATOM 4135 C C   . TYR B 1 35  ? 181.062 156.424 150.461 1.00 1.77  ? 19  TYR B C   1 
ATOM 4136 O O   . TYR B 1 35  ? 181.771 155.422 150.591 1.00 1.77  ? 19  TYR B O   1 
ATOM 4137 C CB  . TYR B 1 35  ? 179.085 156.567 148.918 1.00 1.77  ? 19  TYR B CB  1 
ATOM 4138 C CG  . TYR B 1 35  ? 178.183 157.718 149.283 1.00 1.77  ? 19  TYR B CG  1 
ATOM 4139 C CD1 . TYR B 1 35  ? 177.545 157.779 150.508 1.00 1.77  ? 19  TYR B CD1 1 
ATOM 4140 C CD2 . TYR B 1 35  ? 177.942 158.732 148.370 1.00 1.77  ? 19  TYR B CD2 1 
ATOM 4141 C CE1 . TYR B 1 35  ? 176.708 158.834 150.823 1.00 1.77  ? 19  TYR B CE1 1 
ATOM 4142 C CE2 . TYR B 1 35  ? 177.108 159.785 148.673 1.00 1.77  ? 19  TYR B CE2 1 
ATOM 4143 C CZ  . TYR B 1 35  ? 176.492 159.833 149.902 1.00 1.77  ? 19  TYR B CZ  1 
ATOM 4144 O OH  . TYR B 1 35  ? 175.659 160.885 150.210 1.00 1.77  ? 19  TYR B OH  1 
ATOM 4145 N N   . THR B 1 36  ? 180.682 157.168 151.498 1.00 2.32  ? 20  THR B N   1 
ATOM 4146 C CA  . THR B 1 36  ? 181.089 156.832 152.858 1.00 2.32  ? 20  THR B CA  1 
ATOM 4147 C C   . THR B 1 36  ? 179.965 157.103 153.855 1.00 2.32  ? 20  THR B C   1 
ATOM 4148 O O   . THR B 1 36  ? 180.222 157.330 155.043 1.00 2.32  ? 20  THR B O   1 
ATOM 4149 C CB  . THR B 1 36  ? 182.381 157.590 153.207 1.00 2.32  ? 20  THR B CB  1 
ATOM 4150 O OG1 . THR B 1 36  ? 183.118 156.873 154.208 1.00 2.32  ? 20  THR B OG1 1 
ATOM 4151 C CG2 . THR B 1 36  ? 182.122 159.041 153.636 1.00 2.32  ? 20  THR B CG2 1 
ATOM 4152 N N   . PHE B 1 37  ? 178.718 156.985 153.386 1.00 3.09  ? 21  PHE B N   1 
ATOM 4153 C CA  . PHE B 1 37  ? 177.512 157.394 154.104 1.00 3.09  ? 21  PHE B CA  1 
ATOM 4154 C C   . PHE B 1 37  ? 177.585 157.144 155.604 1.00 3.09  ? 21  PHE B C   1 
ATOM 4155 O O   . PHE B 1 37  ? 177.674 155.997 156.052 1.00 3.09  ? 21  PHE B O   1 
ATOM 4156 C CB  . PHE B 1 37  ? 176.292 156.674 153.521 1.00 3.09  ? 21  PHE B CB  1 
ATOM 4157 C CG  . PHE B 1 37  ? 175.099 156.649 154.435 1.00 3.09  ? 21  PHE B CG  1 
ATOM 4158 C CD1 . PHE B 1 37  ? 174.490 157.825 154.844 1.00 3.09  ? 21  PHE B CD1 1 
ATOM 4159 C CD2 . PHE B 1 37  ? 174.576 155.446 154.869 1.00 3.09  ? 21  PHE B CD2 1 
ATOM 4160 C CE1 . PHE B 1 37  ? 173.394 157.797 155.681 1.00 3.09  ? 21  PHE B CE1 1 
ATOM 4161 C CE2 . PHE B 1 37  ? 173.480 155.413 155.704 1.00 3.09  ? 21  PHE B CE2 1 
ATOM 4162 C CZ  . PHE B 1 37  ? 172.887 156.589 156.111 1.00 3.09  ? 21  PHE B CZ  1 
ATOM 4163 N N   . LYS B 1 38  ? 177.540 158.224 156.380 1.00 3.62  ? 22  LYS B N   1 
ATOM 4164 C CA  . LYS B 1 38  ? 177.667 158.186 157.834 1.00 3.62  ? 22  LYS B CA  1 
ATOM 4165 C C   . LYS B 1 38  ? 176.629 159.138 158.415 1.00 3.62  ? 22  LYS B C   1 
ATOM 4166 O O   . LYS B 1 38  ? 176.844 160.353 158.449 1.00 3.62  ? 22  LYS B O   1 
ATOM 4167 C CB  . LYS B 1 38  ? 179.078 158.571 158.267 1.00 3.62  ? 22  LYS B CB  1 
ATOM 4168 C CG  . LYS B 1 38  ? 179.286 158.578 159.769 1.00 3.62  ? 22  LYS B CG  1 
ATOM 4169 C CD  . LYS B 1 38  ? 180.665 159.100 160.134 1.00 3.62  ? 22  LYS B CD  1 
ATOM 4170 C CE  . LYS B 1 38  ? 180.753 159.420 161.617 1.00 3.62  ? 22  LYS B CE  1 
ATOM 4171 N NZ  . LYS B 1 38  ? 181.960 160.227 161.947 1.00 3.62  ? 22  LYS B NZ  1 
ATOM 4172 N N   . ASP B 1 39  ? 175.504 158.592 158.868 1.00 5.33  ? 23  ASP B N   1 
ATOM 4173 C CA  . ASP B 1 39  ? 174.431 159.407 159.418 1.00 5.33  ? 23  ASP B CA  1 
ATOM 4174 C C   . ASP B 1 39  ? 174.626 159.566 160.919 1.00 5.33  ? 23  ASP B C   1 
ATOM 4175 O O   . ASP B 1 39  ? 174.810 158.579 161.638 1.00 5.33  ? 23  ASP B O   1 
ATOM 4176 C CB  . ASP B 1 39  ? 173.063 158.793 159.120 1.00 5.33  ? 23  ASP B CB  1 
ATOM 4177 C CG  . ASP B 1 39  ? 172.967 157.340 159.534 1.00 5.33  ? 23  ASP B CG  1 
ATOM 4178 O OD1 . ASP B 1 39  ? 173.994 156.632 159.486 1.00 5.33  ? 23  ASP B OD1 1 
ATOM 4179 O OD2 . ASP B 1 39  ? 171.856 156.906 159.902 1.00 5.33  ? 23  ASP B OD2 1 
ATOM 4180 N N   . ARG B 1 40  ? 174.589 160.813 161.385 1.00 7.37  ? 24  ARG B N   1 
ATOM 4181 C CA  . ARG B 1 40  ? 174.752 161.103 162.803 1.00 7.37  ? 24  ARG B CA  1 
ATOM 4182 C C   . ARG B 1 40  ? 173.417 160.967 163.522 1.00 7.37  ? 24  ARG B C   1 
ATOM 4183 O O   . ARG B 1 40  ? 172.974 161.895 164.206 1.00 7.37  ? 24  ARG B O   1 
ATOM 4184 C CB  . ARG B 1 40  ? 175.329 162.507 162.998 1.00 7.37  ? 24  ARG B CB  1 
ATOM 4185 C CG  . ARG B 1 40  ? 174.690 163.571 162.115 1.00 7.37  ? 24  ARG B CG  1 
ATOM 4186 C CD  . ARG B 1 40  ? 175.676 164.674 161.761 1.00 7.37  ? 24  ARG B CD  1 
ATOM 4187 N NE  . ARG B 1 40  ? 176.825 164.170 161.020 1.00 7.37  ? 24  ARG B NE  1 
ATOM 4188 C CZ  . ARG B 1 40  ? 176.827 163.921 159.717 1.00 7.37  ? 24  ARG B CZ  1 
ATOM 4189 N NH1 . ARG B 1 40  ? 175.752 164.124 158.973 1.00 7.37  ? 24  ARG B NH1 1 
ATOM 4190 N NH2 . ARG B 1 40  ? 177.935 163.458 159.146 1.00 7.37  ? 24  ARG B NH2 1 
ATOM 4191 N N   . SER B 1 41  ? 172.768 159.810 163.376 1.00 7.69  ? 25  SER B N   1 
ATOM 4192 C CA  . SER B 1 41  ? 171.458 159.595 163.976 1.00 7.69  ? 25  SER B CA  1 
ATOM 4193 C C   . SER B 1 41  ? 171.349 158.216 164.616 1.00 7.69  ? 25  SER B C   1 
ATOM 4194 O O   . SER B 1 41  ? 170.253 157.649 164.689 1.00 7.69  ? 25  SER B O   1 
ATOM 4195 C CB  . SER B 1 41  ? 170.344 159.784 162.946 1.00 7.69  ? 25  SER B CB  1 
ATOM 4196 O OG  . SER B 1 41  ? 170.179 161.154 162.624 1.00 7.69  ? 25  SER B OG  1 
ATOM 4197 N N   . HIS B 1 42  ? 172.464 157.658 165.079 1.00 5.57  ? 26  HIS B N   1 
ATOM 4198 C CA  . HIS B 1 42  ? 172.427 156.430 165.873 1.00 5.57  ? 26  HIS B CA  1 
ATOM 4199 C C   . HIS B 1 42  ? 172.323 156.736 167.364 1.00 5.57  ? 26  HIS B C   1 
ATOM 4200 O O   . HIS B 1 42  ? 173.104 156.261 168.186 1.00 5.57  ? 26  HIS B O   1 
ATOM 4201 C CB  . HIS B 1 42  ? 173.643 155.564 165.573 1.00 5.57  ? 26  HIS B CB  1 
ATOM 4202 C CG  . HIS B 1 42  ? 173.391 154.517 164.534 1.00 5.57  ? 26  HIS B CG  1 
ATOM 4203 N ND1 . HIS B 1 42  ? 174.372 153.660 164.086 1.00 5.57  ? 26  HIS B ND1 1 
ATOM 4204 C CD2 . HIS B 1 42  ? 172.263 154.179 163.867 1.00 5.57  ? 26  HIS B CD2 1 
ATOM 4205 C CE1 . HIS B 1 42  ? 173.860 152.842 163.183 1.00 5.57  ? 26  HIS B CE1 1 
ATOM 4206 N NE2 . HIS B 1 42  ? 172.582 153.137 163.032 1.00 5.57  ? 26  HIS B NE2 1 
ATOM 4207 N N   . SER B 1 43  ? 171.329 157.553 167.708 1.00 6.00  ? 27  SER B N   1 
ATOM 4208 C CA  . SER B 1 43  ? 170.979 157.816 169.096 1.00 6.00  ? 27  SER B CA  1 
ATOM 4209 C C   . SER B 1 43  ? 169.483 157.764 169.351 1.00 6.00  ? 27  SER B C   1 
ATOM 4210 O O   . SER B 1 43  ? 169.081 157.748 170.518 1.00 6.00  ? 27  SER B O   1 
ATOM 4211 C CB  . SER B 1 43  ? 171.517 159.184 169.540 1.00 6.00  ? 27  SER B CB  1 
ATOM 4212 O OG  . SER B 1 43  ? 170.857 160.238 168.860 1.00 6.00  ? 27  SER B OG  1 
ATOM 4213 N N   . GLY B 1 44  ? 168.649 157.744 168.315 1.00 7.02  ? 28  GLY B N   1 
ATOM 4214 C CA  . GLY B 1 44  ? 167.218 157.598 168.481 1.00 7.02  ? 28  GLY B CA  1 
ATOM 4215 C C   . GLY B 1 44  ? 166.706 156.319 167.853 1.00 7.02  ? 28  GLY B C   1 
ATOM 4216 O O   . GLY B 1 44  ? 165.517 156.001 167.948 1.00 7.02  ? 28  GLY B O   1 
ATOM 4217 N N   . ARG B 1 45  ? 167.604 155.576 167.202 1.00 7.16  ? 29  ARG B N   1 
ATOM 4218 C CA  . ARG B 1 45  ? 167.259 154.299 166.595 1.00 7.16  ? 29  ARG B CA  1 
ATOM 4219 C C   . ARG B 1 45  ? 167.964 153.112 167.232 1.00 7.16  ? 29  ARG B C   1 
ATOM 4220 O O   . ARG B 1 45  ? 167.527 151.976 167.027 1.00 7.16  ? 29  ARG B O   1 
ATOM 4221 C CB  . ARG B 1 45  ? 167.580 154.314 165.094 1.00 7.16  ? 29  ARG B CB  1 
ATOM 4222 C CG  . ARG B 1 45  ? 166.657 155.190 164.265 1.00 7.16  ? 29  ARG B CG  1 
ATOM 4223 C CD  . ARG B 1 45  ? 167.175 155.340 162.845 1.00 7.16  ? 29  ARG B CD  1 
ATOM 4224 N NE  . ARG B 1 45  ? 167.246 154.057 162.156 1.00 7.16  ? 29  ARG B NE  1 
ATOM 4225 C CZ  . ARG B 1 45  ? 168.374 153.469 161.784 1.00 7.16  ? 29  ARG B CZ  1 
ATOM 4226 N NH1 . ARG B 1 45  ? 169.552 154.022 162.018 1.00 7.16  ? 29  ARG B NH1 1 
ATOM 4227 N NH2 . ARG B 1 45  ? 168.319 152.295 161.161 1.00 7.16  ? 29  ARG B NH2 1 
ATOM 4228 N N   . VAL B 1 46  ? 169.035 153.340 167.989 1.00 4.72  ? 30  VAL B N   1 
ATOM 4229 C CA  . VAL B 1 46  ? 169.742 152.277 168.689 1.00 4.72  ? 30  VAL B CA  1 
ATOM 4230 C C   . VAL B 1 46  ? 169.751 152.482 170.196 1.00 4.72  ? 30  VAL B C   1 
ATOM 4231 O O   . VAL B 1 46  ? 169.713 151.499 170.944 1.00 4.72  ? 30  VAL B O   1 
ATOM 4232 C CB  . VAL B 1 46  ? 171.181 152.125 168.150 1.00 4.72  ? 30  VAL B CB  1 
ATOM 4233 C CG1 . VAL B 1 46  ? 172.107 151.489 169.177 1.00 4.72  ? 30  VAL B CG1 1 
ATOM 4234 C CG2 . VAL B 1 46  ? 171.173 151.312 166.869 1.00 4.72  ? 30  VAL B CG2 1 
ATOM 4235 N N   . ALA B 1 47  ? 169.734 153.726 170.666 1.00 7.62  ? 31  ALA B N   1 
ATOM 4236 C CA  . ALA B 1 47  ? 169.614 154.022 172.088 1.00 7.62  ? 31  ALA B CA  1 
ATOM 4237 C C   . ALA B 1 47  ? 168.173 154.069 172.564 1.00 7.62  ? 31  ALA B C   1 
ATOM 4238 O O   . ALA B 1 47  ? 167.848 153.469 173.589 1.00 7.62  ? 31  ALA B O   1 
ATOM 4239 C CB  . ALA B 1 47  ? 170.296 155.355 172.414 1.00 7.62  ? 31  ALA B CB  1 
ATOM 4240 N N   . GLN B 1 48  ? 167.298 154.768 171.840 1.00 8.17  ? 32  GLN B N   1 
ATOM 4241 C CA  . GLN B 1 48  ? 165.884 154.782 172.191 1.00 8.17  ? 32  GLN B CA  1 
ATOM 4242 C C   . GLN B 1 48  ? 165.199 153.471 171.828 1.00 8.17  ? 32  GLN B C   1 
ATOM 4243 O O   . GLN B 1 48  ? 164.266 153.051 172.522 1.00 8.17  ? 32  GLN B O   1 
ATOM 4244 C CB  . GLN B 1 48  ? 165.182 155.955 171.503 1.00 8.17  ? 32  GLN B CB  1 
ATOM 4245 C CG  . GLN B 1 48  ? 163.707 156.118 171.859 1.00 8.17  ? 32  GLN B CG  1 
ATOM 4246 C CD  . GLN B 1 48  ? 163.474 156.460 173.322 1.00 8.17  ? 32  GLN B CD  1 
ATOM 4247 O OE1 . GLN B 1 48  ? 164.409 156.769 174.061 1.00 8.17  ? 32  GLN B OE1 1 
ATOM 4248 N NE2 . GLN B 1 48  ? 162.217 156.405 173.745 1.00 8.17  ? 32  GLN B NE2 1 
ATOM 4249 N N   . GLY B 1 49  ? 165.645 152.812 170.760 1.00 5.47  ? 33  GLY B N   1 
ATOM 4250 C CA  . GLY B 1 49  ? 165.071 151.540 170.370 1.00 5.47  ? 33  GLY B CA  1 
ATOM 4251 C C   . GLY B 1 49  ? 165.475 150.365 171.230 1.00 5.47  ? 33  GLY B C   1 
ATOM 4252 O O   . GLY B 1 49  ? 164.914 149.277 171.073 1.00 5.47  ? 33  GLY B O   1 
ATOM 4253 N N   . ILE B 1 50  ? 166.438 150.558 172.129 1.00 6.87  ? 34  ILE B N   1 
ATOM 4254 C CA  . ILE B 1 50  ? 166.850 149.519 173.068 1.00 6.87  ? 34  ILE B CA  1 
ATOM 4255 C C   . ILE B 1 50  ? 166.202 149.679 174.435 1.00 6.87  ? 34  ILE B C   1 
ATOM 4256 O O   . ILE B 1 50  ? 165.849 148.663 175.057 1.00 6.87  ? 34  ILE B O   1 
ATOM 4257 C CB  . ILE B 1 50  ? 168.388 149.464 173.202 1.00 6.87  ? 34  ILE B CB  1 
ATOM 4258 C CG1 . ILE B 1 50  ? 168.989 148.621 172.074 1.00 6.87  ? 34  ILE B CG1 1 
ATOM 4259 C CG2 . ILE B 1 50  ? 168.819 148.924 174.560 1.00 6.87  ? 34  ILE B CG2 1 
ATOM 4260 C CD1 . ILE B 1 50  ? 168.831 147.133 172.270 1.00 6.87  ? 34  ILE B CD1 1 
ATOM 4261 N N   . MET B 1 51  ? 166.000 150.914 174.907 1.00 12.76 ? 35  MET B N   1 
ATOM 4262 C CA  . MET B 1 51  ? 165.336 151.121 176.191 1.00 12.76 ? 35  MET B CA  1 
ATOM 4263 C C   . MET B 1 51  ? 163.943 150.510 176.212 1.00 12.76 ? 35  MET B C   1 
ATOM 4264 O O   . MET B 1 51  ? 163.580 149.834 177.181 1.00 12.76 ? 35  MET B O   1 
ATOM 4265 C CB  . MET B 1 51  ? 165.242 152.612 176.506 1.00 12.76 ? 35  MET B CB  1 
ATOM 4266 C CG  . MET B 1 51  ? 166.508 153.233 177.059 1.00 12.76 ? 35  MET B CG  1 
ATOM 4267 S SD  . MET B 1 51  ? 166.417 155.036 177.089 1.00 12.76 ? 35  MET B SD  1 
ATOM 4268 C CE  . MET B 1 51  ? 164.645 155.301 177.063 1.00 12.76 ? 35  MET B CE  1 
ATOM 4269 N N   . LYS B 1 52  ? 163.153 150.729 175.162 1.00 9.16  ? 36  LYS B N   1 
ATOM 4270 C CA  . LYS B 1 52  ? 161.810 150.173 175.097 1.00 9.16  ? 36  LYS B CA  1 
ATOM 4271 C C   . LYS B 1 52  ? 161.803 148.675 174.830 1.00 9.16  ? 36  LYS B C   1 
ATOM 4272 O O   . LYS B 1 52  ? 160.762 148.034 175.009 1.00 9.16  ? 36  LYS B O   1 
ATOM 4273 C CB  . LYS B 1 52  ? 160.991 150.888 174.017 1.00 9.16  ? 36  LYS B CB  1 
ATOM 4274 C CG  . LYS B 1 52  ? 161.173 150.324 172.619 1.00 9.16  ? 36  LYS B CG  1 
ATOM 4275 C CD  . LYS B 1 52  ? 160.033 150.741 171.704 1.00 9.16  ? 36  LYS B CD  1 
ATOM 4276 C CE  . LYS B 1 52  ? 160.398 150.544 170.242 1.00 9.16  ? 36  LYS B CE  1 
ATOM 4277 N NZ  . LYS B 1 52  ? 160.204 149.134 169.806 1.00 9.16  ? 36  LYS B NZ  1 
ATOM 4278 N N   . LEU B 1 53  ? 162.931 148.106 174.408 1.00 6.26  ? 37  LEU B N   1 
ATOM 4279 C CA  . LEU B 1 53  ? 163.022 146.674 174.165 1.00 6.26  ? 37  LEU B CA  1 
ATOM 4280 C C   . LEU B 1 53  ? 163.639 145.912 175.329 1.00 6.26  ? 37  LEU B C   1 
ATOM 4281 O O   . LEU B 1 53  ? 163.528 144.682 175.373 1.00 6.26  ? 37  LEU B O   1 
ATOM 4282 C CB  . LEU B 1 53  ? 163.835 146.407 172.895 1.00 6.26  ? 37  LEU B CB  1 
ATOM 4283 C CG  . LEU B 1 53  ? 163.468 145.155 172.099 1.00 6.26  ? 37  LEU B CG  1 
ATOM 4284 C CD1 . LEU B 1 53  ? 161.981 145.132 171.808 1.00 6.26  ? 37  LEU B CD1 1 
ATOM 4285 C CD2 . LEU B 1 53  ? 164.265 145.095 170.811 1.00 6.26  ? 37  LEU B CD2 1 
ATOM 4286 N N   . CYS B 1 54  ? 164.282 146.604 176.263 1.00 5.63  ? 38  CYS B N   1 
ATOM 4287 C CA  . CYS B 1 54  ? 164.904 145.976 177.422 1.00 5.63  ? 38  CYS B CA  1 
ATOM 4288 C C   . CYS B 1 54  ? 164.329 146.448 178.746 1.00 5.63  ? 38  CYS B C   1 
ATOM 4289 O O   . CYS B 1 54  ? 163.993 145.619 179.596 1.00 5.63  ? 38  CYS B O   1 
ATOM 4290 C CB  . CYS B 1 54  ? 166.417 146.235 177.413 1.00 5.63  ? 38  CYS B CB  1 
ATOM 4291 S SG  . CYS B 1 54  ? 167.400 144.885 176.746 1.00 5.63  ? 38  CYS B SG  1 
ATOM 4292 N N   . LEU B 1 55  ? 164.207 147.759 178.948 1.00 8.14  ? 39  LEU B N   1 
ATOM 4293 C CA  . LEU B 1 55  ? 163.756 148.278 180.235 1.00 8.14  ? 39  LEU B CA  1 
ATOM 4294 C C   . LEU B 1 55  ? 162.237 148.241 180.352 1.00 8.14  ? 39  LEU B C   1 
ATOM 4295 O O   . LEU B 1 55  ? 161.687 147.573 181.234 1.00 8.14  ? 39  LEU B O   1 
ATOM 4296 C CB  . LEU B 1 55  ? 164.276 149.704 180.433 1.00 8.14  ? 39  LEU B CB  1 
ATOM 4297 C CG  . LEU B 1 55  ? 165.793 149.879 180.491 1.00 8.14  ? 39  LEU B CG  1 
ATOM 4298 C CD1 . LEU B 1 55  ? 166.149 151.239 181.067 1.00 8.14  ? 39  LEU B CD1 1 
ATOM 4299 C CD2 . LEU B 1 55  ? 166.433 148.765 181.301 1.00 8.14  ? 39  LEU B CD2 1 
ATOM 4300 N N   . GLU B 1 56  ? 161.540 148.952 179.465 1.00 12.28 ? 40  GLU B N   1 
ATOM 4301 C CA  . GLU B 1 56  ? 160.090 149.065 179.579 1.00 12.28 ? 40  GLU B CA  1 
ATOM 4302 C C   . GLU B 1 56  ? 159.406 147.751 179.220 1.00 12.28 ? 40  GLU B C   1 
ATOM 4303 O O   . GLU B 1 56  ? 158.746 147.128 180.059 1.00 12.28 ? 40  GLU B O   1 
ATOM 4304 C CB  . GLU B 1 56  ? 159.583 150.203 178.689 1.00 12.28 ? 40  GLU B CB  1 
ATOM 4305 C CG  . GLU B 1 56  ? 160.439 151.468 178.723 1.00 12.28 ? 40  GLU B CG  1 
ATOM 4306 C CD  . GLU B 1 56  ? 160.381 152.215 180.048 1.00 12.28 ? 40  GLU B CD  1 
ATOM 4307 O OE1 . GLU B 1 56  ? 161.023 153.282 180.150 1.00 12.28 ? 40  GLU B OE1 1 
ATOM 4308 O OE2 . GLU B 1 56  ? 159.687 151.758 180.981 1.00 12.28 ? 40  GLU B OE2 1 
ATOM 4309 N N   . GLU B 1 57  ? 159.557 147.310 177.974 1.00 14.11 ? 41  GLU B N   1 
ATOM 4310 C CA  . GLU B 1 57  ? 158.980 146.053 177.507 1.00 14.11 ? 41  GLU B CA  1 
ATOM 4311 C C   . GLU B 1 57  ? 160.079 144.998 177.553 1.00 14.11 ? 41  GLU B C   1 
ATOM 4312 O O   . GLU B 1 57  ? 160.821 144.817 176.585 1.00 14.11 ? 41  GLU B O   1 
ATOM 4313 C CB  . GLU B 1 57  ? 158.403 146.207 176.103 1.00 14.11 ? 41  GLU B CB  1 
ATOM 4314 C CG  . GLU B 1 57  ? 157.271 145.246 175.778 1.00 14.11 ? 41  GLU B CG  1 
ATOM 4315 C CD  . GLU B 1 57  ? 157.755 143.829 175.546 1.00 14.11 ? 41  GLU B CD  1 
ATOM 4316 O OE1 . GLU B 1 57  ? 158.776 143.655 174.848 1.00 14.11 ? 41  GLU B OE1 1 
ATOM 4317 O OE2 . GLU B 1 57  ? 157.115 142.889 176.061 1.00 14.11 ? 41  GLU B OE2 1 
ATOM 4318 N N   . GLU B 1 58  ? 160.185 144.308 178.689 1.00 9.72  ? 42  GLU B N   1 
ATOM 4319 C CA  . GLU B 1 58  ? 161.214 143.292 178.876 1.00 9.72  ? 42  GLU B CA  1 
ATOM 4320 C C   . GLU B 1 58  ? 161.076 142.183 177.842 1.00 9.72  ? 42  GLU B C   1 
ATOM 4321 O O   . GLU B 1 58  ? 160.015 141.562 177.726 1.00 9.72  ? 42  GLU B O   1 
ATOM 4322 C CB  . GLU B 1 58  ? 161.145 142.714 180.291 1.00 9.72  ? 42  GLU B CB  1 
ATOM 4323 C CG  . GLU B 1 58  ? 162.151 141.607 180.556 1.00 9.72  ? 42  GLU B CG  1 
ATOM 4324 C CD  . GLU B 1 58  ? 162.150 141.153 182.001 1.00 9.72  ? 42  GLU B CD  1 
ATOM 4325 O OE1 . GLU B 1 58  ? 161.482 141.805 182.831 1.00 9.72  ? 42  GLU B OE1 1 
ATOM 4326 O OE2 . GLU B 1 58  ? 162.813 140.140 182.307 1.00 9.72  ? 42  GLU B OE2 1 
ATOM 4327 N N   . LEU B 1 59  ? 162.141 141.934 177.085 1.00 5.50  ? 43  LEU B N   1 
ATOM 4328 C CA  . LEU B 1 59  ? 162.115 140.951 176.014 1.00 5.50  ? 43  LEU B CA  1 
ATOM 4329 C C   . LEU B 1 59  ? 163.518 140.401 175.801 1.00 5.50  ? 43  LEU B C   1 
ATOM 4330 O O   . LEU B 1 59  ? 164.513 141.016 176.192 1.00 5.50  ? 43  LEU B O   1 
ATOM 4331 C CB  . LEU B 1 59  ? 161.574 141.562 174.713 1.00 5.50  ? 43  LEU B CB  1 
ATOM 4332 C CG  . LEU B 1 59  ? 160.793 140.650 173.767 1.00 5.50  ? 43  LEU B CG  1 
ATOM 4333 C CD1 . LEU B 1 59  ? 159.678 139.933 174.508 1.00 5.50  ? 43  LEU B CD1 1 
ATOM 4334 C CD2 . LEU B 1 59  ? 160.235 141.451 172.602 1.00 5.50  ? 43  LEU B CD2 1 
ATOM 4335 N N   . PHE B 1 60  ? 163.579 139.224 175.177 1.00 4.33  ? 44  PHE B N   1 
ATOM 4336 C CA  . PHE B 1 60  ? 164.841 138.581 174.802 1.00 4.33  ? 44  PHE B CA  1 
ATOM 4337 C C   . PHE B 1 60  ? 165.714 138.297 176.024 1.00 4.33  ? 44  PHE B C   1 
ATOM 4338 O O   . PHE B 1 60  ? 166.912 138.587 176.043 1.00 4.33  ? 44  PHE B O   1 
ATOM 4339 C CB  . PHE B 1 60  ? 165.597 139.424 173.771 1.00 4.33  ? 44  PHE B CB  1 
ATOM 4340 C CG  . PHE B 1 60  ? 164.832 139.655 172.500 1.00 4.33  ? 44  PHE B CG  1 
ATOM 4341 C CD1 . PHE B 1 60  ? 164.035 138.658 171.966 1.00 4.33  ? 44  PHE B CD1 1 
ATOM 4342 C CD2 . PHE B 1 60  ? 164.908 140.870 171.842 1.00 4.33  ? 44  PHE B CD2 1 
ATOM 4343 C CE1 . PHE B 1 60  ? 163.330 138.869 170.796 1.00 4.33  ? 44  PHE B CE1 1 
ATOM 4344 C CE2 . PHE B 1 60  ? 164.206 141.086 170.673 1.00 4.33  ? 44  PHE B CE2 1 
ATOM 4345 C CZ  . PHE B 1 60  ? 163.416 140.085 170.150 1.00 4.33  ? 44  PHE B CZ  1 
ATOM 4346 N N   . ALA B 1 61  ? 165.102 137.718 177.054 1.00 5.47  ? 45  ALA B N   1 
ATOM 4347 C CA  . ALA B 1 61  ? 165.847 137.332 178.244 1.00 5.47  ? 45  ALA B CA  1 
ATOM 4348 C C   . ALA B 1 61  ? 166.650 136.065 177.978 1.00 5.47  ? 45  ALA B C   1 
ATOM 4349 O O   . ALA B 1 61  ? 166.162 135.124 177.347 1.00 5.47  ? 45  ALA B O   1 
ATOM 4350 C CB  . ALA B 1 61  ? 164.896 137.116 179.420 1.00 5.47  ? 45  ALA B CB  1 
ATOM 4351 N N   . ASP B 1 62  ? 167.891 136.042 178.462 1.00 7.38  ? 46  ASP B N   1 
ATOM 4352 C CA  . ASP B 1 62  ? 168.784 134.915 178.217 1.00 7.38  ? 46  ASP B CA  1 
ATOM 4353 C C   . ASP B 1 62  ? 169.256 134.225 179.488 1.00 7.38  ? 46  ASP B C   1 
ATOM 4354 O O   . ASP B 1 62  ? 169.207 132.992 179.565 1.00 7.38  ? 46  ASP B O   1 
ATOM 4355 C CB  . ASP B 1 62  ? 169.988 135.372 177.371 1.00 7.38  ? 46  ASP B CB  1 
ATOM 4356 C CG  . ASP B 1 62  ? 170.712 136.565 177.965 1.00 7.38  ? 46  ASP B CG  1 
ATOM 4357 O OD1 . ASP B 1 62  ? 171.159 137.431 177.185 1.00 7.38  ? 46  ASP B OD1 1 
ATOM 4358 O OD2 . ASP B 1 62  ? 170.840 136.642 179.203 1.00 7.38  ? 46  ASP B OD2 1 
ATOM 4359 N N   . VAL B 1 63  ? 169.712 134.972 180.492 1.00 6.88  ? 47  VAL B N   1 
ATOM 4360 C CA  . VAL B 1 63  ? 170.265 134.390 181.710 1.00 6.88  ? 47  VAL B CA  1 
ATOM 4361 C C   . VAL B 1 63  ? 169.243 134.524 182.831 1.00 6.88  ? 47  VAL B C   1 
ATOM 4362 O O   . VAL B 1 63  ? 168.593 135.564 182.975 1.00 6.88  ? 47  VAL B O   1 
ATOM 4363 C CB  . VAL B 1 63  ? 171.608 135.042 182.106 1.00 6.88  ? 47  VAL B CB  1 
ATOM 4364 C CG1 . VAL B 1 63  ? 171.449 136.535 182.332 1.00 6.88  ? 47  VAL B CG1 1 
ATOM 4365 C CG2 . VAL B 1 63  ? 172.185 134.370 183.342 1.00 6.88  ? 47  VAL B CG2 1 
ATOM 4366 N N   . THR B 1 64  ? 169.089 133.458 183.611 1.00 7.16  ? 48  THR B N   1 
ATOM 4367 C CA  . THR B 1 64  ? 168.151 133.420 184.725 1.00 7.16  ? 48  THR B CA  1 
ATOM 4368 C C   . THR B 1 64  ? 168.917 133.492 186.038 1.00 7.16  ? 48  THR B C   1 
ATOM 4369 O O   . THR B 1 64  ? 169.848 132.711 186.262 1.00 7.16  ? 48  THR B O   1 
ATOM 4370 C CB  . THR B 1 64  ? 167.301 132.150 184.684 1.00 7.16  ? 48  THR B CB  1 
ATOM 4371 O OG1 . THR B 1 64  ? 168.103 131.025 185.064 1.00 7.16  ? 48  THR B OG1 1 
ATOM 4372 C CG2 . THR B 1 64  ? 166.754 131.922 183.285 1.00 7.16  ? 48  THR B CG2 1 
ATOM 4373 N N   . ILE B 1 65  ? 168.520 134.421 186.902 1.00 5.89  ? 49  ILE B N   1 
ATOM 4374 C CA  . ILE B 1 65  ? 169.128 134.594 188.216 1.00 5.89  ? 49  ILE B CA  1 
ATOM 4375 C C   . ILE B 1 65  ? 168.266 133.854 189.226 1.00 5.89  ? 49  ILE B C   1 
ATOM 4376 O O   . ILE B 1 65  ? 167.088 134.184 189.407 1.00 5.89  ? 49  ILE B O   1 
ATOM 4377 C CB  . ILE B 1 65  ? 169.255 136.079 188.586 1.00 5.89  ? 49  ILE B CB  1 
ATOM 4378 C CG1 . ILE B 1 65  ? 170.046 136.836 187.521 1.00 5.89  ? 49  ILE B CG1 1 
ATOM 4379 C CG2 . ILE B 1 65  ? 169.923 136.226 189.939 1.00 5.89  ? 49  ILE B CG2 1 
ATOM 4380 C CD1 . ILE B 1 65  ? 171.472 136.387 187.392 1.00 5.89  ? 49  ILE B CD1 1 
ATOM 4381 N N   . SER B 1 66  ? 168.846 132.855 189.890 1.00 6.92  ? 50  SER B N   1 
ATOM 4382 C CA  . SER B 1 66  ? 168.100 132.017 190.826 1.00 6.92  ? 50  SER B CA  1 
ATOM 4383 C C   . SER B 1 66  ? 168.457 132.419 192.254 1.00 6.92  ? 50  SER B C   1 
ATOM 4384 O O   . SER B 1 66  ? 169.310 131.820 192.908 1.00 6.92  ? 50  SER B O   1 
ATOM 4385 C CB  . SER B 1 66  ? 168.386 130.541 190.568 1.00 6.92  ? 50  SER B CB  1 
ATOM 4386 O OG  . SER B 1 66  ? 168.153 129.769 191.733 1.00 6.92  ? 50  SER B OG  1 
ATOM 4387 N N   . VAL B 1 67  ? 167.772 133.453 192.743 1.00 8.97  ? 51  VAL B N   1 
ATOM 4388 C CA  . VAL B 1 67  ? 167.857 133.786 194.158 1.00 8.97  ? 51  VAL B CA  1 
ATOM 4389 C C   . VAL B 1 67  ? 167.090 132.735 194.958 1.00 8.97  ? 51  VAL B C   1 
ATOM 4390 O O   . VAL B 1 67  ? 166.264 131.988 194.420 1.00 8.97  ? 51  VAL B O   1 
ATOM 4391 C CB  . VAL B 1 67  ? 167.310 135.206 194.398 1.00 8.97  ? 51  VAL B CB  1 
ATOM 4392 C CG1 . VAL B 1 67  ? 165.933 135.351 193.780 1.00 8.97  ? 51  VAL B CG1 1 
ATOM 4393 C CG2 . VAL B 1 67  ? 167.315 135.607 195.874 1.00 8.97  ? 51  VAL B CG2 1 
ATOM 4394 N N   . GLU B 1 68  ? 167.391 132.652 196.255 1.00 14.58 ? 52  GLU B N   1 
ATOM 4395 C CA  . GLU B 1 68  ? 166.741 131.672 197.117 1.00 14.58 ? 52  GLU B CA  1 
ATOM 4396 C C   . GLU B 1 68  ? 165.223 131.805 197.034 1.00 14.58 ? 52  GLU B C   1 
ATOM 4397 O O   . GLU B 1 68  ? 164.680 132.915 197.065 1.00 14.58 ? 52  GLU B O   1 
ATOM 4398 C CB  . GLU B 1 68  ? 167.247 131.818 198.560 1.00 14.58 ? 52  GLU B CB  1 
ATOM 4399 C CG  . GLU B 1 68  ? 166.371 132.640 199.496 1.00 14.58 ? 52  GLU B CG  1 
ATOM 4400 C CD  . GLU B 1 68  ? 167.079 133.012 200.784 1.00 14.58 ? 52  GLU B CD  1 
ATOM 4401 O OE1 . GLU B 1 68  ? 168.291 132.734 200.899 1.00 14.58 ? 52  GLU B OE1 1 
ATOM 4402 O OE2 . GLU B 1 68  ? 166.426 133.585 201.680 1.00 14.58 ? 52  GLU B OE2 1 
ATOM 4403 N N   . GLY B 1 69  ? 164.536 130.678 196.863 1.00 13.36 ? 53  GLY B N   1 
ATOM 4404 C CA  . GLY B 1 69  ? 163.089 130.671 196.787 1.00 13.36 ? 53  GLY B CA  1 
ATOM 4405 C C   . GLY B 1 69  ? 162.511 130.863 195.397 1.00 13.36 ? 53  GLY B C   1 
ATOM 4406 O O   . GLY B 1 69  ? 161.631 130.103 194.982 1.00 13.36 ? 53  GLY B O   1 
ATOM 4407 N N   . ARG B 1 70  ? 162.994 131.863 194.665 1.00 9.96  ? 54  ARG B N   1 
ATOM 4408 C CA  . ARG B 1 70  ? 162.414 132.257 193.389 1.00 9.96  ? 54  ARG B CA  1 
ATOM 4409 C C   . ARG B 1 70  ? 163.397 132.000 192.248 1.00 9.96  ? 54  ARG B C   1 
ATOM 4410 O O   . ARG B 1 70  ? 164.462 131.403 192.435 1.00 9.96  ? 54  ARG B O   1 
ATOM 4411 C CB  . ARG B 1 70  ? 161.986 133.725 193.441 1.00 9.96  ? 54  ARG B CB  1 
ATOM 4412 C CG  . ARG B 1 70  ? 160.512 133.932 193.736 1.00 9.96  ? 54  ARG B CG  1 
ATOM 4413 C CD  . ARG B 1 70  ? 160.111 135.385 193.537 1.00 9.96  ? 54  ARG B CD  1 
ATOM 4414 N NE  . ARG B 1 70  ? 161.028 136.302 194.204 1.00 9.96  ? 54  ARG B NE  1 
ATOM 4415 C CZ  . ARG B 1 70  ? 161.045 136.528 195.510 1.00 9.96  ? 54  ARG B CZ  1 
ATOM 4416 N NH1 . ARG B 1 70  ? 160.202 135.921 196.329 1.00 9.96  ? 54  ARG B NH1 1 
ATOM 4417 N NH2 . ARG B 1 70  ? 161.931 137.387 196.008 1.00 9.96  ? 54  ARG B NH2 1 
ATOM 4418 N N   . GLU B 1 71  ? 163.022 132.445 191.047 1.00 7.23  ? 55  GLU B N   1 
ATOM 4419 C CA  . GLU B 1 71  ? 163.877 132.303 189.868 1.00 7.23  ? 55  GLU B CA  1 
ATOM 4420 C C   . GLU B 1 71  ? 163.534 133.438 188.907 1.00 7.23  ? 55  GLU B C   1 
ATOM 4421 O O   . GLU B 1 71  ? 162.526 133.369 188.197 1.00 7.23  ? 55  GLU B O   1 
ATOM 4422 C CB  . GLU B 1 71  ? 163.690 130.940 189.216 1.00 7.23  ? 55  GLU B CB  1 
ATOM 4423 C CG  . GLU B 1 71  ? 164.510 130.742 187.953 1.00 7.23  ? 55  GLU B CG  1 
ATOM 4424 C CD  . GLU B 1 71  ? 164.369 129.347 187.380 1.00 7.23  ? 55  GLU B CD  1 
ATOM 4425 O OE1 . GLU B 1 71  ? 163.747 128.491 188.042 1.00 7.23  ? 55  GLU B OE1 1 
ATOM 4426 O OE2 . GLU B 1 71  ? 164.878 129.107 186.265 1.00 7.23  ? 55  GLU B OE2 1 
ATOM 4427 N N   . PHE B 1 72  ? 164.371 134.473 188.890 1.00 5.07  ? 56  PHE B N   1 
ATOM 4428 C CA  . PHE B 1 72  ? 164.159 135.613 188.014 1.00 5.07  ? 56  PHE B CA  1 
ATOM 4429 C C   . PHE B 1 72  ? 164.769 135.364 186.636 1.00 5.07  ? 56  PHE B C   1 
ATOM 4430 O O   . PHE B 1 72  ? 165.493 134.392 186.407 1.00 5.07  ? 56  PHE B O   1 
ATOM 4431 C CB  . PHE B 1 72  ? 164.752 136.882 188.624 1.00 5.07  ? 56  PHE B CB  1 
ATOM 4432 C CG  . PHE B 1 72  ? 164.012 137.380 189.829 1.00 5.07  ? 56  PHE B CG  1 
ATOM 4433 C CD1 . PHE B 1 72  ? 164.308 136.898 191.090 1.00 5.07  ? 56  PHE B CD1 1 
ATOM 4434 C CD2 . PHE B 1 72  ? 163.021 138.336 189.699 1.00 5.07  ? 56  PHE B CD2 1 
ATOM 4435 C CE1 . PHE B 1 72  ? 163.626 137.358 192.198 1.00 5.07  ? 56  PHE B CE1 1 
ATOM 4436 C CE2 . PHE B 1 72  ? 162.337 138.799 190.803 1.00 5.07  ? 56  PHE B CE2 1 
ATOM 4437 C CZ  . PHE B 1 72  ? 162.640 138.309 192.055 1.00 5.07  ? 56  PHE B CZ  1 
ATOM 4438 N N   . GLN B 1 73  ? 164.461 136.269 185.708 1.00 3.64  ? 57  GLN B N   1 
ATOM 4439 C CA  . GLN B 1 73  ? 165.031 136.249 184.366 1.00 3.64  ? 57  GLN B CA  1 
ATOM 4440 C C   . GLN B 1 73  ? 165.502 137.654 184.031 1.00 3.64  ? 57  GLN B C   1 
ATOM 4441 O O   . GLN B 1 73  ? 164.690 138.582 183.971 1.00 3.64  ? 57  GLN B O   1 
ATOM 4442 C CB  . GLN B 1 73  ? 164.012 135.759 183.333 1.00 3.64  ? 57  GLN B CB  1 
ATOM 4443 C CG  . GLN B 1 73  ? 163.804 134.255 183.335 1.00 3.64  ? 57  GLN B CG  1 
ATOM 4444 C CD  . GLN B 1 73  ? 163.070 133.768 182.103 1.00 3.64  ? 57  GLN B CD  1 
ATOM 4445 O OE1 . GLN B 1 73  ? 163.686 133.439 181.089 1.00 3.64  ? 57  GLN B OE1 1 
ATOM 4446 N NE2 . GLN B 1 73  ? 161.746 133.718 182.184 1.00 3.64  ? 57  GLN B NE2 1 
ATOM 4447 N N   . LEU B 1 74  ? 166.804 137.809 183.806 1.00 2.99  ? 58  LEU B N   1 
ATOM 4448 C CA  . LEU B 1 74  ? 167.414 139.113 183.605 1.00 2.99  ? 58  LEU B CA  1 
ATOM 4449 C C   . LEU B 1 74  ? 168.224 139.116 182.317 1.00 2.99  ? 58  LEU B C   1 
ATOM 4450 O O   . LEU B 1 74  ? 168.680 138.070 181.850 1.00 2.99  ? 58  LEU B O   1 
ATOM 4451 C CB  . LEU B 1 74  ? 168.309 139.490 184.792 1.00 2.99  ? 58  LEU B CB  1 
ATOM 4452 C CG  . LEU B 1 74  ? 167.592 139.664 186.132 1.00 2.99  ? 58  LEU B CG  1 
ATOM 4453 C CD1 . LEU B 1 74  ? 168.517 140.268 187.174 1.00 2.99  ? 58  LEU B CD1 1 
ATOM 4454 C CD2 . LEU B 1 74  ? 166.351 140.524 185.964 1.00 2.99  ? 58  LEU B CD2 1 
ATOM 4455 N N   . HIS B 1 75  ? 168.393 140.303 181.743 1.00 3.63  ? 59  HIS B N   1 
ATOM 4456 C CA  . HIS B 1 75  ? 169.148 140.446 180.508 1.00 3.63  ? 59  HIS B CA  1 
ATOM 4457 C C   . HIS B 1 75  ? 170.638 140.586 180.796 1.00 3.63  ? 59  HIS B C   1 
ATOM 4458 O O   . HIS B 1 75  ? 171.049 141.159 181.808 1.00 3.63  ? 59  HIS B O   1 
ATOM 4459 C CB  . HIS B 1 75  ? 168.657 141.655 179.715 1.00 3.63  ? 59  HIS B CB  1 
ATOM 4460 C CG  . HIS B 1 75  ? 167.201 141.602 179.378 1.00 3.63  ? 59  HIS B CG  1 
ATOM 4461 N ND1 . HIS B 1 75  ? 166.436 140.470 179.558 1.00 3.63  ? 59  HIS B ND1 1 
ATOM 4462 C CD2 . HIS B 1 75  ? 166.366 142.543 178.877 1.00 3.63  ? 59  HIS B CD2 1 
ATOM 4463 C CE1 . HIS B 1 75  ? 165.195 140.715 179.180 1.00 3.63  ? 59  HIS B CE1 1 
ATOM 4464 N NE2 . HIS B 1 75  ? 165.125 141.966 178.763 1.00 3.63  ? 59  HIS B NE2 1 
ATOM 4465 N N   . ARG B 1 76  ? 171.451 140.051 179.885 1.00 4.30  ? 60  ARG B N   1 
ATOM 4466 C CA  . ARG B 1 76  ? 172.899 140.087 180.044 1.00 4.30  ? 60  ARG B CA  1 
ATOM 4467 C C   . ARG B 1 76  ? 173.496 141.459 179.766 1.00 4.30  ? 60  ARG B C   1 
ATOM 4468 O O   . ARG B 1 76  ? 174.624 141.720 180.197 1.00 4.30  ? 60  ARG B O   1 
ATOM 4469 C CB  . ARG B 1 76  ? 173.549 139.058 179.120 1.00 4.30  ? 60  ARG B CB  1 
ATOM 4470 C CG  . ARG B 1 76  ? 173.874 137.735 179.783 1.00 4.30  ? 60  ARG B CG  1 
ATOM 4471 C CD  . ARG B 1 76  ? 174.498 136.777 178.785 1.00 4.30  ? 60  ARG B CD  1 
ATOM 4472 N NE  . ARG B 1 76  ? 175.376 135.809 179.428 1.00 4.30  ? 60  ARG B NE  1 
ATOM 4473 C CZ  . ARG B 1 76  ? 176.203 135.004 178.776 1.00 4.30  ? 60  ARG B CZ  1 
ATOM 4474 N NH1 . ARG B 1 76  ? 176.294 135.029 177.456 1.00 4.30  ? 60  ARG B NH1 1 
ATOM 4475 N NH2 . ARG B 1 76  ? 176.956 134.152 179.465 1.00 4.30  ? 60  ARG B NH2 1 
ATOM 4476 N N   . LEU B 1 77  ? 172.782 142.334 179.061 1.00 2.69  ? 61  LEU B N   1 
ATOM 4477 C CA  . LEU B 1 77  ? 173.317 143.636 178.683 1.00 2.69  ? 61  LEU B CA  1 
ATOM 4478 C C   . LEU B 1 77  ? 172.966 144.743 179.663 1.00 2.69  ? 61  LEU B C   1 
ATOM 4479 O O   . LEU B 1 77  ? 173.717 145.718 179.770 1.00 2.69  ? 61  LEU B O   1 
ATOM 4480 C CB  . LEU B 1 77  ? 172.820 144.029 177.288 1.00 2.69  ? 61  LEU B CB  1 
ATOM 4481 C CG  . LEU B 1 77  ? 173.734 143.692 176.111 1.00 2.69  ? 61  LEU B CG  1 
ATOM 4482 C CD1 . LEU B 1 77  ? 173.864 142.190 175.941 1.00 2.69  ? 61  LEU B CD1 1 
ATOM 4483 C CD2 . LEU B 1 77  ? 173.210 144.329 174.837 1.00 2.69  ? 61  LEU B CD2 1 
ATOM 4484 N N   . VAL B 1 78  ? 171.849 144.626 180.376 1.00 1.66  ? 62  VAL B N   1 
ATOM 4485 C CA  . VAL B 1 78  ? 171.474 145.651 181.341 1.00 1.66  ? 62  VAL B CA  1 
ATOM 4486 C C   . VAL B 1 78  ? 172.179 145.454 182.680 1.00 1.66  ? 62  VAL B C   1 
ATOM 4487 O O   . VAL B 1 78  ? 172.519 146.435 183.348 1.00 1.66  ? 62  VAL B O   1 
ATOM 4488 C CB  . VAL B 1 78  ? 169.948 145.679 181.520 1.00 1.66  ? 62  VAL B CB  1 
ATOM 4489 C CG1 . VAL B 1 78  ? 169.535 146.879 182.346 1.00 1.66  ? 62  VAL B CG1 1 
ATOM 4490 C CG2 . VAL B 1 78  ? 169.263 145.707 180.168 1.00 1.66  ? 62  VAL B CG2 1 
ATOM 4491 N N   . LEU B 1 79  ? 172.410 144.204 183.086 1.00 1.62  ? 63  LEU B N   1 
ATOM 4492 C CA  . LEU B 1 79  ? 173.096 143.948 184.348 1.00 1.62  ? 63  LEU B CA  1 
ATOM 4493 C C   . LEU B 1 79  ? 174.547 144.410 184.313 1.00 1.62  ? 63  LEU B C   1 
ATOM 4494 O O   . LEU B 1 79  ? 175.043 144.958 185.304 1.00 1.62  ? 63  LEU B O   1 
ATOM 4495 C CB  . LEU B 1 79  ? 173.024 142.461 184.689 1.00 1.62  ? 63  LEU B CB  1 
ATOM 4496 C CG  . LEU B 1 79  ? 172.015 142.062 185.763 1.00 1.62  ? 63  LEU B CG  1 
ATOM 4497 C CD1 . LEU B 1 79  ? 170.654 142.654 185.460 1.00 1.62  ? 63  LEU B CD1 1 
ATOM 4498 C CD2 . LEU B 1 79  ? 171.930 140.551 185.859 1.00 1.62  ? 63  LEU B CD2 1 
ATOM 4499 N N   . SER B 1 80  ? 175.239 144.203 183.196 1.00 1.54  ? 64  SER B N   1 
ATOM 4500 C CA  . SER B 1 80  ? 176.649 144.545 183.082 1.00 1.54  ? 64  SER B CA  1 
ATOM 4501 C C   . SER B 1 80  ? 176.885 145.989 182.661 1.00 1.54  ? 64  SER B C   1 
ATOM 4502 O O   . SER B 1 80  ? 178.043 146.410 182.576 1.00 1.54  ? 64  SER B O   1 
ATOM 4503 C CB  . SER B 1 80  ? 177.342 143.605 182.092 1.00 1.54  ? 64  SER B CB  1 
ATOM 4504 O OG  . SER B 1 80  ? 177.444 142.297 182.623 1.00 1.54  ? 64  SER B OG  1 
ATOM 4505 N N   . ALA B 1 81  ? 175.829 146.754 182.394 1.00 1.05  ? 65  ALA B N   1 
ATOM 4506 C CA  . ALA B 1 81  ? 175.987 148.152 182.020 1.00 1.05  ? 65  ALA B CA  1 
ATOM 4507 C C   . ALA B 1 81  ? 175.963 149.096 183.213 1.00 1.05  ? 65  ALA B C   1 
ATOM 4508 O O   . ALA B 1 81  ? 176.516 150.198 183.123 1.00 1.05  ? 65  ALA B O   1 
ATOM 4509 C CB  . ALA B 1 81  ? 174.894 148.564 181.030 1.00 1.05  ? 65  ALA B CB  1 
ATOM 4510 N N   . GLN B 1 82  ? 175.342 148.694 184.324 1.00 1.67  ? 66  GLN B N   1 
ATOM 4511 C CA  . GLN B 1 82  ? 175.278 149.525 185.517 1.00 1.67  ? 66  GLN B CA  1 
ATOM 4512 C C   . GLN B 1 82  ? 176.139 149.019 186.663 1.00 1.67  ? 66  GLN B C   1 
ATOM 4513 O O   . GLN B 1 82  ? 176.502 149.813 187.536 1.00 1.67  ? 66  GLN B O   1 
ATOM 4514 C CB  . GLN B 1 82  ? 173.829 149.643 186.011 1.00 1.67  ? 66  GLN B CB  1 
ATOM 4515 C CG  . GLN B 1 82  ? 172.793 149.594 184.908 1.00 1.67  ? 66  GLN B CG  1 
ATOM 4516 C CD  . GLN B 1 82  ? 171.381 149.676 185.440 1.00 1.67  ? 66  GLN B CD  1 
ATOM 4517 O OE1 . GLN B 1 82  ? 171.153 150.141 186.555 1.00 1.67  ? 66  GLN B OE1 1 
ATOM 4518 N NE2 . GLN B 1 82  ? 170.422 149.226 184.644 1.00 1.67  ? 66  GLN B NE2 1 
ATOM 4519 N N   . SER B 1 83  ? 176.474 147.735 186.682 1.00 2.51  ? 67  SER B N   1 
ATOM 4520 C CA  . SER B 1 83  ? 177.261 147.139 187.748 1.00 2.51  ? 67  SER B CA  1 
ATOM 4521 C C   . SER B 1 83  ? 178.664 146.817 187.253 1.00 2.51  ? 67  SER B C   1 
ATOM 4522 O O   . SER B 1 83  ? 178.987 146.958 186.071 1.00 2.51  ? 67  SER B O   1 
ATOM 4523 C CB  . SER B 1 83  ? 176.578 145.873 188.278 1.00 2.51  ? 67  SER B CB  1 
ATOM 4524 O OG  . SER B 1 83  ? 177.511 145.028 188.927 1.00 2.51  ? 67  SER B OG  1 
ATOM 4525 N N   . CYS B 1 84  ? 179.504 146.387 188.186 1.00 4.13  ? 68  CYS B N   1 
ATOM 4526 C CA  . CYS B 1 84  ? 180.850 145.919 187.883 1.00 4.13  ? 68  CYS B CA  1 
ATOM 4527 C C   . CYS B 1 84  ? 181.099 144.502 188.369 1.00 4.13  ? 68  CYS B C   1 
ATOM 4528 O O   . CYS B 1 84  ? 181.767 143.728 187.680 1.00 4.13  ? 68  CYS B O   1 
ATOM 4529 C CB  . CYS B 1 84  ? 181.893 146.863 188.498 1.00 4.13  ? 68  CYS B CB  1 
ATOM 4530 S SG  . CYS B 1 84  ? 183.573 146.198 188.545 1.00 4.13  ? 68  CYS B SG  1 
ATOM 4531 N N   . PHE B 1 85  ? 180.577 144.143 189.543 1.00 3.20  ? 69  PHE B N   1 
ATOM 4532 C CA  . PHE B 1 85  ? 180.647 142.756 189.988 1.00 3.20  ? 69  PHE B CA  1 
ATOM 4533 C C   . PHE B 1 85  ? 179.841 141.850 189.068 1.00 3.20  ? 69  PHE B C   1 
ATOM 4534 O O   . PHE B 1 85  ? 180.257 140.723 188.776 1.00 3.20  ? 69  PHE B O   1 
ATOM 4535 C CB  . PHE B 1 85  ? 180.156 142.642 191.431 1.00 3.20  ? 69  PHE B CB  1 
ATOM 4536 C CG  . PHE B 1 85  ? 179.764 141.248 191.833 1.00 3.20  ? 69  PHE B CG  1 
ATOM 4537 C CD1 . PHE B 1 85  ? 180.723 140.330 192.218 1.00 3.20  ? 69  PHE B CD1 1 
ATOM 4538 C CD2 . PHE B 1 85  ? 178.435 140.861 191.840 1.00 3.20  ? 69  PHE B CD2 1 
ATOM 4539 C CE1 . PHE B 1 85  ? 180.366 139.050 192.592 1.00 3.20  ? 69  PHE B CE1 1 
ATOM 4540 C CE2 . PHE B 1 85  ? 178.072 139.583 192.213 1.00 3.20  ? 69  PHE B CE2 1 
ATOM 4541 C CZ  . PHE B 1 85  ? 179.038 138.677 192.589 1.00 3.20  ? 69  PHE B CZ  1 
ATOM 4542 N N   . PHE B 1 86  ? 178.683 142.323 188.606 1.00 3.22  ? 70  PHE B N   1 
ATOM 4543 C CA  . PHE B 1 86  ? 177.884 141.559 187.658 1.00 3.22  ? 70  PHE B CA  1 
ATOM 4544 C C   . PHE B 1 86  ? 178.513 141.498 186.272 1.00 3.22  ? 70  PHE B C   1 
ATOM 4545 O O   . PHE B 1 86  ? 178.156 140.612 185.491 1.00 3.22  ? 70  PHE B O   1 
ATOM 4546 C CB  . PHE B 1 86  ? 176.477 142.149 187.562 1.00 3.22  ? 70  PHE B CB  1 
ATOM 4547 C CG  . PHE B 1 86  ? 175.475 141.472 188.452 1.00 3.22  ? 70  PHE B CG  1 
ATOM 4548 C CD1 . PHE B 1 86  ? 175.501 140.100 188.627 1.00 3.22  ? 70  PHE B CD1 1 
ATOM 4549 C CD2 . PHE B 1 86  ? 174.504 142.208 189.109 1.00 3.22  ? 70  PHE B CD2 1 
ATOM 4550 C CE1 . PHE B 1 86  ? 174.580 139.474 189.443 1.00 3.22  ? 70  PHE B CE1 1 
ATOM 4551 C CE2 . PHE B 1 86  ? 173.580 141.588 189.927 1.00 3.22  ? 70  PHE B CE2 1 
ATOM 4552 C CZ  . PHE B 1 86  ? 173.619 140.219 190.094 1.00 3.22  ? 70  PHE B CZ  1 
ATOM 4553 N N   . ARG B 1 87  ? 179.435 142.404 185.950 1.00 3.99  ? 71  ARG B N   1 
ATOM 4554 C CA  . ARG B 1 87  ? 180.129 142.372 184.668 1.00 3.99  ? 71  ARG B CA  1 
ATOM 4555 C C   . ARG B 1 87  ? 181.366 141.490 184.685 1.00 3.99  ? 71  ARG B C   1 
ATOM 4556 O O   . ARG B 1 87  ? 181.634 140.798 183.698 1.00 3.99  ? 71  ARG B O   1 
ATOM 4557 C CB  . ARG B 1 87  ? 180.534 143.787 184.244 1.00 3.99  ? 71  ARG B CB  1 
ATOM 4558 C CG  . ARG B 1 87  ? 181.307 143.841 182.938 1.00 3.99  ? 71  ARG B CG  1 
ATOM 4559 C CD  . ARG B 1 87  ? 181.932 145.214 182.712 1.00 3.99  ? 71  ARG B CD  1 
ATOM 4560 N NE  . ARG B 1 87  ? 182.291 145.467 181.320 1.00 3.99  ? 71  ARG B NE  1 
ATOM 4561 C CZ  . ARG B 1 87  ? 183.115 144.723 180.591 1.00 3.99  ? 71  ARG B CZ  1 
ATOM 4562 N NH1 . ARG B 1 87  ? 183.748 143.679 181.101 1.00 3.99  ? 71  ARG B NH1 1 
ATOM 4563 N NH2 . ARG B 1 87  ? 183.324 145.047 179.318 1.00 3.99  ? 71  ARG B NH2 1 
ATOM 4564 N N   . SER B 1 88  ? 182.117 141.488 185.783 1.00 5.40  ? 72  SER B N   1 
ATOM 4565 C CA  . SER B 1 88  ? 183.291 140.637 185.913 1.00 5.40  ? 72  SER B CA  1 
ATOM 4566 C C   . SER B 1 88  ? 182.937 139.189 186.219 1.00 5.40  ? 72  SER B C   1 
ATOM 4567 O O   . SER B 1 88  ? 183.846 138.373 186.404 1.00 5.40  ? 72  SER B O   1 
ATOM 4568 C CB  . SER B 1 88  ? 184.218 141.179 187.003 1.00 5.40  ? 72  SER B CB  1 
ATOM 4569 O OG  . SER B 1 88  ? 185.436 140.456 187.038 1.00 5.40  ? 72  SER B OG  1 
ATOM 4570 N N   . MET B 1 89  ? 181.650 138.855 186.289 1.00 6.61  ? 73  MET B N   1 
ATOM 4571 C CA  . MET B 1 89  ? 181.208 137.503 186.601 1.00 6.61  ? 73  MET B CA  1 
ATOM 4572 C C   . MET B 1 89  ? 180.625 136.793 185.384 1.00 6.61  ? 73  MET B C   1 
ATOM 4573 O O   . MET B 1 89  ? 180.902 135.609 185.168 1.00 6.61  ? 73  MET B O   1 
ATOM 4574 C CB  . MET B 1 89  ? 180.193 137.547 187.749 1.00 6.61  ? 73  MET B CB  1 
ATOM 4575 C CG  . MET B 1 89  ? 179.337 136.311 187.910 1.00 6.61  ? 73  MET B CG  1 
ATOM 4576 S SD  . MET B 1 89  ? 178.544 136.323 189.528 1.00 6.61  ? 73  MET B SD  1 
ATOM 4577 C CE  . MET B 1 89  ? 177.159 135.236 189.239 1.00 6.61  ? 73  MET B CE  1 
ATOM 4578 N N   . PHE B 1 90  ? 179.822 137.493 184.577 1.00 6.99  ? 74  PHE B N   1 
ATOM 4579 C CA  . PHE B 1 90  ? 179.392 136.928 183.300 1.00 6.99  ? 74  PHE B CA  1 
ATOM 4580 C C   . PHE B 1 90  ? 180.553 136.834 182.317 1.00 6.99  ? 74  PHE B C   1 
ATOM 4581 O O   . PHE B 1 90  ? 180.608 135.906 181.502 1.00 6.99  ? 74  PHE B O   1 
ATOM 4582 C CB  . PHE B 1 90  ? 178.256 137.755 182.697 1.00 6.99  ? 74  PHE B CB  1 
ATOM 4583 C CG  . PHE B 1 90  ? 176.953 137.634 183.434 1.00 6.99  ? 74  PHE B CG  1 
ATOM 4584 C CD1 . PHE B 1 90  ? 176.362 138.742 184.012 1.00 6.99  ? 74  PHE B CD1 1 
ATOM 4585 C CD2 . PHE B 1 90  ? 176.317 136.411 183.544 1.00 6.99  ? 74  PHE B CD2 1 
ATOM 4586 C CE1 . PHE B 1 90  ? 175.163 138.634 184.687 1.00 6.99  ? 74  PHE B CE1 1 
ATOM 4587 C CE2 . PHE B 1 90  ? 175.118 136.296 184.219 1.00 6.99  ? 74  PHE B CE2 1 
ATOM 4588 C CZ  . PHE B 1 90  ? 174.541 137.409 184.791 1.00 6.99  ? 74  PHE B CZ  1 
ATOM 4589 N N   . THR B 1 91  ? 181.484 137.792 182.370 1.00 11.83 ? 75  THR B N   1 
ATOM 4590 C CA  . THR B 1 91  ? 182.611 137.785 181.442 1.00 11.83 ? 75  THR B CA  1 
ATOM 4591 C C   . THR B 1 91  ? 183.479 136.547 181.631 1.00 11.83 ? 75  THR B C   1 
ATOM 4592 O O   . THR B 1 91  ? 183.899 135.918 180.653 1.00 11.83 ? 75  THR B O   1 
ATOM 4593 C CB  . THR B 1 91  ? 183.445 139.055 181.618 1.00 11.83 ? 75  THR B CB  1 
ATOM 4594 O OG1 . THR B 1 91  ? 182.653 140.200 181.278 1.00 11.83 ? 75  THR B OG1 1 
ATOM 4595 C CG2 . THR B 1 91  ? 184.675 139.018 180.724 1.00 11.83 ? 75  THR B CG2 1 
ATOM 4596 N N   . SER B 1 92  ? 183.753 136.177 182.880 1.00 14.02 ? 76  SER B N   1 
ATOM 4597 C CA  . SER B 1 92  ? 184.555 134.994 183.172 1.00 14.02 ? 76  SER B CA  1 
ATOM 4598 C C   . SER B 1 92  ? 183.664 133.762 183.071 1.00 14.02 ? 76  SER B C   1 
ATOM 4599 O O   . SER B 1 92  ? 182.767 133.566 183.897 1.00 14.02 ? 76  SER B O   1 
ATOM 4600 C CB  . SER B 1 92  ? 185.188 135.103 184.555 1.00 14.02 ? 76  SER B CB  1 
ATOM 4601 O OG  . SER B 1 92  ? 184.198 135.263 185.556 1.00 14.02 ? 76  SER B OG  1 
ATOM 4602 N N   . ASN B 1 93  ? 183.912 132.928 182.059 1.00 20.20 ? 77  ASN B N   1 
ATOM 4603 C CA  . ASN B 1 93  ? 183.131 131.718 181.827 1.00 20.20 ? 77  ASN B CA  1 
ATOM 4604 C C   . ASN B 1 93  ? 183.726 130.494 182.511 1.00 20.20 ? 77  ASN B C   1 
ATOM 4605 O O   . ASN B 1 93  ? 183.534 129.367 182.035 1.00 20.20 ? 77  ASN B O   1 
ATOM 4606 C CB  . ASN B 1 93  ? 182.982 131.470 180.325 1.00 20.20 ? 77  ASN B CB  1 
ATOM 4607 C CG  . ASN B 1 93  ? 182.170 132.546 179.635 1.00 20.20 ? 77  ASN B CG  1 
ATOM 4608 O OD1 . ASN B 1 93  ? 181.236 133.102 180.214 1.00 20.20 ? 77  ASN B OD1 1 
ATOM 4609 N ND2 . ASN B 1 93  ? 182.521 132.846 178.390 1.00 20.20 ? 77  ASN B ND2 1 
ATOM 4610 N N   . LEU B 1 94  ? 184.443 130.683 183.619 1.00 23.55 ? 78  LEU B N   1 
ATOM 4611 C CA  . LEU B 1 94  ? 185.049 129.574 184.356 1.00 23.55 ? 78  LEU B CA  1 
ATOM 4612 C C   . LEU B 1 94  ? 183.956 128.868 185.154 1.00 23.55 ? 78  LEU B C   1 
ATOM 4613 O O   . LEU B 1 94  ? 183.870 128.964 186.381 1.00 23.55 ? 78  LEU B O   1 
ATOM 4614 C CB  . LEU B 1 94  ? 186.171 130.074 185.256 1.00 23.55 ? 78  LEU B CB  1 
ATOM 4615 C CG  . LEU B 1 94  ? 187.597 129.935 184.717 1.00 23.55 ? 78  LEU B CG  1 
ATOM 4616 C CD1 . LEU B 1 94  ? 187.950 128.471 184.507 1.00 23.55 ? 78  LEU B CD1 1 
ATOM 4617 C CD2 . LEU B 1 94  ? 187.772 130.725 183.428 1.00 23.55 ? 78  LEU B CD2 1 
ATOM 4618 N N   . LYS B 1 95  ? 183.105 128.141 184.425 1.00 26.02 ? 79  LYS B N   1 
ATOM 4619 C CA  . LYS B 1 95  ? 181.987 127.395 185.007 1.00 26.02 ? 79  LYS B CA  1 
ATOM 4620 C C   . LYS B 1 95  ? 181.064 128.303 185.816 1.00 26.02 ? 79  LYS B C   1 
ATOM 4621 O O   . LYS B 1 95  ? 180.537 127.909 186.859 1.00 26.02 ? 79  LYS B O   1 
ATOM 4622 C CB  . LYS B 1 95  ? 182.486 126.229 185.866 1.00 26.02 ? 79  LYS B CB  1 
ATOM 4623 C CG  . LYS B 1 95  ? 183.070 125.066 185.073 1.00 26.02 ? 79  LYS B CG  1 
ATOM 4624 C CD  . LYS B 1 95  ? 182.375 124.891 183.731 1.00 26.02 ? 79  LYS B CD  1 
ATOM 4625 C CE  . LYS B 1 95  ? 183.158 123.955 182.824 1.00 26.02 ? 79  LYS B CE  1 
ATOM 4626 N NZ  . LYS B 1 95  ? 182.919 124.246 181.383 1.00 26.02 ? 79  LYS B NZ  1 
ATOM 4627 N N   . GLU B 1 96  ? 180.863 129.533 185.336 1.00 25.84 ? 80  GLU B N   1 
ATOM 4628 C CA  . GLU B 1 96  ? 179.995 130.493 186.001 1.00 25.84 ? 80  GLU B CA  1 
ATOM 4629 C C   . GLU B 1 96  ? 178.905 131.066 185.108 1.00 25.84 ? 80  GLU B C   1 
ATOM 4630 O O   . GLU B 1 96  ? 178.018 131.756 185.621 1.00 25.84 ? 80  GLU B O   1 
ATOM 4631 C CB  . GLU B 1 96  ? 180.819 131.657 186.577 1.00 25.84 ? 80  GLU B CB  1 
ATOM 4632 C CG  . GLU B 1 96  ? 181.809 131.242 187.654 1.00 25.84 ? 80  GLU B CG  1 
ATOM 4633 C CD  . GLU B 1 96  ? 182.751 132.364 188.044 1.00 25.84 ? 80  GLU B CD  1 
ATOM 4634 O OE1 . GLU B 1 96  ? 183.094 133.187 187.168 1.00 25.84 ? 80  GLU B OE1 1 
ATOM 4635 O OE2 . GLU B 1 96  ? 183.149 132.424 189.227 1.00 25.84 ? 80  GLU B OE2 1 
ATOM 4636 N N   . ALA B 1 97  ? 178.943 130.809 183.800 1.00 21.06 ? 81  ALA B N   1 
ATOM 4637 C CA  . ALA B 1 97  ? 177.922 131.301 182.888 1.00 21.06 ? 81  ALA B CA  1 
ATOM 4638 C C   . ALA B 1 97  ? 177.396 130.237 181.935 1.00 21.06 ? 81  ALA B C   1 
ATOM 4639 O O   . ALA B 1 97  ? 176.383 130.477 181.269 1.00 21.06 ? 81  ALA B O   1 
ATOM 4640 C CB  . ALA B 1 97  ? 178.458 132.488 182.073 1.00 21.06 ? 81  ALA B CB  1 
ATOM 4641 N N   . HIS B 1 98  ? 178.049 129.076 181.846 1.00 24.30 ? 82  HIS B N   1 
ATOM 4642 C CA  . HIS B 1 98  ? 177.595 128.032 180.935 1.00 24.30 ? 82  HIS B CA  1 
ATOM 4643 C C   . HIS B 1 98  ? 176.328 127.346 181.428 1.00 24.30 ? 82  HIS B C   1 
ATOM 4644 O O   . HIS B 1 98  ? 175.521 126.886 180.612 1.00 24.30 ? 82  HIS B O   1 
ATOM 4645 C CB  . HIS B 1 98  ? 178.701 126.995 180.731 1.00 24.30 ? 82  HIS B CB  1 
ATOM 4646 C CG  . HIS B 1 98  ? 179.844 127.485 179.899 1.00 24.30 ? 82  HIS B CG  1 
ATOM 4647 N ND1 . HIS B 1 98  ? 179.691 127.901 178.594 1.00 24.30 ? 82  HIS B ND1 1 
ATOM 4648 C CD2 . HIS B 1 98  ? 181.160 127.624 180.186 1.00 24.30 ? 82  HIS B CD2 1 
ATOM 4649 C CE1 . HIS B 1 98  ? 180.863 128.277 178.113 1.00 24.30 ? 82  HIS B CE1 1 
ATOM 4650 N NE2 . HIS B 1 98  ? 181.771 128.118 179.059 1.00 24.30 ? 82  HIS B NE2 1 
ATOM 4651 N N   . ASN B 1 99  ? 176.136 127.264 182.746 1.00 23.50 ? 83  ASN B N   1 
ATOM 4652 C CA  . ASN B 1 99  ? 174.971 126.575 183.289 1.00 23.50 ? 83  ASN B CA  1 
ATOM 4653 C C   . ASN B 1 99  ? 173.687 127.372 183.099 1.00 23.50 ? 83  ASN B C   1 
ATOM 4654 O O   . ASN B 1 99  ? 172.622 126.779 182.891 1.00 23.50 ? 83  ASN B O   1 
ATOM 4655 C CB  . ASN B 1 99  ? 175.187 126.273 184.772 1.00 23.50 ? 83  ASN B CB  1 
ATOM 4656 C CG  . ASN B 1 99  ? 176.540 125.647 185.045 1.00 23.50 ? 83  ASN B CG  1 
ATOM 4657 O OD1 . ASN B 1 99  ? 177.084 124.927 184.207 1.00 23.50 ? 83  ASN B OD1 1 
ATOM 4658 N ND2 . ASN B 1 99  ? 177.093 125.921 186.221 1.00 23.50 ? 83  ASN B ND2 1 
ATOM 4659 N N   . ARG B 1 100 ? 173.765 128.701 183.185 1.00 17.56 ? 84  ARG B N   1 
ATOM 4660 C CA  . ARG B 1 100 ? 172.629 129.606 183.011 1.00 17.56 ? 84  ARG B CA  1 
ATOM 4661 C C   . ARG B 1 100 ? 171.544 129.393 184.064 1.00 17.56 ? 84  ARG B C   1 
ATOM 4662 O O   . ARG B 1 100 ? 170.428 129.902 183.922 1.00 17.56 ? 84  ARG B O   1 
ATOM 4663 C CB  . ARG B 1 100 ? 172.031 129.490 181.603 1.00 17.56 ? 84  ARG B CB  1 
ATOM 4664 C CG  . ARG B 1 100 ? 172.555 130.528 180.622 1.00 17.56 ? 84  ARG B CG  1 
ATOM 4665 C CD  . ARG B 1 100 ? 171.788 130.490 179.309 1.00 17.56 ? 84  ARG B CD  1 
ATOM 4666 N NE  . ARG B 1 100 ? 170.346 130.541 179.521 1.00 17.56 ? 84  ARG B NE  1 
ATOM 4667 C CZ  . ARG B 1 100 ? 169.443 130.123 178.645 1.00 17.56 ? 84  ARG B CZ  1 
ATOM 4668 N NH1 . ARG B 1 100 ? 169.796 129.612 177.478 1.00 17.56 ? 84  ARG B NH1 1 
ATOM 4669 N NH2 . ARG B 1 100 ? 168.151 130.221 178.949 1.00 17.56 ? 84  ARG B NH2 1 
ATOM 4670 N N   . VAL B 1 101 ? 171.849 128.644 185.123 1.00 12.58 ? 85  VAL B N   1 
ATOM 4671 C CA  . VAL B 1 101 ? 170.934 128.465 186.245 1.00 12.58 ? 85  VAL B CA  1 
ATOM 4672 C C   . VAL B 1 101 ? 171.706 128.949 187.469 1.00 12.58 ? 85  VAL B C   1 
ATOM 4673 O O   . VAL B 1 101 ? 171.666 128.340 188.544 1.00 12.58 ? 85  VAL B O   1 
ATOM 4674 C CB  . VAL B 1 101 ? 170.460 127.000 186.364 1.00 12.58 ? 85  VAL B CB  1 
ATOM 4675 C CG1 . VAL B 1 101 ? 169.449 126.814 187.501 1.00 12.58 ? 85  VAL B CG1 1 
ATOM 4676 C CG2 . VAL B 1 101 ? 169.869 126.520 185.047 1.00 12.58 ? 85  VAL B CG2 1 
ATOM 4677 N N   . ILE B 1 102 ? 172.461 130.036 187.288 1.00 10.78 ? 86  ILE B N   1 
ATOM 4678 C CA  . ILE B 1 102 ? 173.327 130.538 188.346 1.00 10.78 ? 86  ILE B CA  1 
ATOM 4679 C C   . ILE B 1 102 ? 172.500 130.973 189.549 1.00 10.78 ? 86  ILE B C   1 
ATOM 4680 O O   . ILE B 1 102 ? 171.375 131.469 189.414 1.00 10.78 ? 86  ILE B O   1 
ATOM 4681 C CB  . ILE B 1 102 ? 174.210 131.678 187.806 1.00 10.78 ? 86  ILE B CB  1 
ATOM 4682 C CG1 . ILE B 1 102 ? 173.401 132.961 187.631 1.00 10.78 ? 86  ILE B CG1 1 
ATOM 4683 C CG2 . ILE B 1 102 ? 174.844 131.278 186.487 1.00 10.78 ? 86  ILE B CG2 1 
ATOM 4684 C CD1 . ILE B 1 102 ? 174.248 134.199 187.613 1.00 10.78 ? 86  ILE B CD1 1 
ATOM 4685 N N   . VAL B 1 103 ? 173.055 130.759 190.740 1.00 7.67  ? 87  VAL B N   1 
ATOM 4686 C CA  . VAL B 1 103 ? 172.374 131.020 192.002 1.00 7.67  ? 87  VAL B CA  1 
ATOM 4687 C C   . VAL B 1 103 ? 173.155 132.069 192.782 1.00 7.67  ? 87  VAL B C   1 
ATOM 4688 O O   . VAL B 1 103 ? 174.388 132.013 192.858 1.00 7.67  ? 87  VAL B O   1 
ATOM 4689 C CB  . VAL B 1 103 ? 172.212 129.723 192.821 1.00 7.67  ? 87  VAL B CB  1 
ATOM 4690 C CG1 . VAL B 1 103 ? 173.524 128.953 192.870 1.00 7.67  ? 87  VAL B CG1 1 
ATOM 4691 C CG2 . VAL B 1 103 ? 171.713 130.027 194.225 1.00 7.67  ? 87  VAL B CG2 1 
ATOM 4692 N N   . LEU B 1 104 ? 172.435 133.033 193.353 1.00 7.71  ? 88  LEU B N   1 
ATOM 4693 C CA  . LEU B 1 104 ? 173.019 134.090 194.168 1.00 7.71  ? 88  LEU B CA  1 
ATOM 4694 C C   . LEU B 1 104 ? 172.775 133.791 195.641 1.00 7.71  ? 88  LEU B C   1 
ATOM 4695 O O   . LEU B 1 104 ? 171.718 133.264 196.005 1.00 7.71  ? 88  LEU B O   1 
ATOM 4696 C CB  . LEU B 1 104 ? 172.433 135.454 193.802 1.00 7.71  ? 88  LEU B CB  1 
ATOM 4697 C CG  . LEU B 1 104 ? 173.062 136.131 192.585 1.00 7.71  ? 88  LEU B CG  1 
ATOM 4698 C CD1 . LEU B 1 104 ? 172.401 137.468 192.318 1.00 7.71  ? 88  LEU B CD1 1 
ATOM 4699 C CD2 . LEU B 1 104 ? 174.559 136.301 192.783 1.00 7.71  ? 88  LEU B CD2 1 
ATOM 4700 N N   . GLN B 1 105 ? 173.747 134.130 196.481 1.00 11.88 ? 89  GLN B N   1 
ATOM 4701 C CA  . GLN B 1 105 ? 173.702 133.842 197.907 1.00 11.88 ? 89  GLN B CA  1 
ATOM 4702 C C   . GLN B 1 105 ? 173.930 135.110 198.722 1.00 11.88 ? 89  GLN B C   1 
ATOM 4703 O O   . GLN B 1 105 ? 174.368 136.143 198.208 1.00 11.88 ? 89  GLN B O   1 
ATOM 4704 C CB  . GLN B 1 105 ? 174.737 132.771 198.270 1.00 11.88 ? 89  GLN B CB  1 
ATOM 4705 C CG  . GLN B 1 105 ? 176.134 133.057 197.743 1.00 11.88 ? 89  GLN B CG  1 
ATOM 4706 C CD  . GLN B 1 105 ? 176.985 131.807 197.645 1.00 11.88 ? 89  GLN B CD  1 
ATOM 4707 O OE1 . GLN B 1 105 ? 176.495 130.693 197.830 1.00 11.88 ? 89  GLN B OE1 1 
ATOM 4708 N NE2 . GLN B 1 105 ? 178.267 131.985 197.350 1.00 11.88 ? 89  GLN B NE2 1 
ATOM 4709 N N   . ASP B 1 106 ? 173.621 135.008 200.019 1.00 11.90 ? 90  ASP B N   1 
ATOM 4710 C CA  . ASP B 1 106 ? 173.719 136.126 200.963 1.00 11.90 ? 90  ASP B CA  1 
ATOM 4711 C C   . ASP B 1 106 ? 172.869 137.315 200.518 1.00 11.90 ? 90  ASP B C   1 
ATOM 4712 O O   . ASP B 1 106 ? 173.219 138.473 200.753 1.00 11.90 ? 90  ASP B O   1 
ATOM 4713 C CB  . ASP B 1 106 ? 175.173 136.553 201.184 1.00 11.90 ? 90  ASP B CB  1 
ATOM 4714 C CG  . ASP B 1 106 ? 176.094 135.381 201.456 1.00 11.90 ? 90  ASP B CG  1 
ATOM 4715 O OD1 . ASP B 1 106 ? 176.318 134.567 200.537 1.00 11.90 ? 90  ASP B OD1 1 
ATOM 4716 O OD2 . ASP B 1 106 ? 176.596 135.273 202.594 1.00 11.90 ? 90  ASP B OD2 1 
ATOM 4717 N N   . VAL B 1 107 ? 171.741 137.028 199.873 1.00 7.04  ? 91  VAL B N   1 
ATOM 4718 C CA  . VAL B 1 107 ? 170.802 138.055 199.436 1.00 7.04  ? 91  VAL B CA  1 
ATOM 4719 C C   . VAL B 1 107 ? 169.393 137.587 199.765 1.00 7.04  ? 91  VAL B C   1 
ATOM 4720 O O   . VAL B 1 107 ? 168.997 136.480 199.386 1.00 7.04  ? 91  VAL B O   1 
ATOM 4721 C CB  . VAL B 1 107 ? 170.936 138.354 197.930 1.00 7.04  ? 91  VAL B CB  1 
ATOM 4722 C CG1 . VAL B 1 107 ? 169.736 139.134 197.437 1.00 7.04  ? 91  VAL B CG1 1 
ATOM 4723 C CG2 . VAL B 1 107 ? 172.216 139.122 197.657 1.00 7.04  ? 91  VAL B CG2 1 
ATOM 4724 N N   . SER B 1 108 ? 168.636 138.425 200.468 1.00 7.80  ? 92  SER B N   1 
ATOM 4725 C CA  . SER B 1 108 ? 167.274 138.073 200.832 1.00 7.80  ? 92  SER B CA  1 
ATOM 4726 C C   . SER B 1 108 ? 166.355 138.146 199.615 1.00 7.80  ? 92  SER B C   1 
ATOM 4727 O O   . SER B 1 108 ? 166.691 138.727 198.579 1.00 7.80  ? 92  SER B O   1 
ATOM 4728 C CB  . SER B 1 108 ? 166.757 138.991 201.940 1.00 7.80  ? 92  SER B CB  1 
ATOM 4729 O OG  . SER B 1 108 ? 165.350 138.896 202.067 1.00 7.80  ? 92  SER B OG  1 
ATOM 4730 N N   . GLU B 1 109 ? 165.180 137.530 199.750 1.00 9.75  ? 93  GLU B N   1 
ATOM 4731 C CA  . GLU B 1 109 ? 164.228 137.498 198.644 1.00 9.75  ? 93  GLU B CA  1 
ATOM 4732 C C   . GLU B 1 109 ? 163.690 138.888 198.325 1.00 9.75  ? 93  GLU B C   1 
ATOM 4733 O O   . GLU B 1 109 ? 163.559 139.253 197.151 1.00 9.75  ? 93  GLU B O   1 
ATOM 4734 C CB  . GLU B 1 109 ? 163.081 136.543 198.971 1.00 9.75  ? 93  GLU B CB  1 
ATOM 4735 C CG  . GLU B 1 109 ? 163.523 135.122 199.273 1.00 9.75  ? 93  GLU B CG  1 
ATOM 4736 C CD  . GLU B 1 109 ? 162.514 134.364 200.113 1.00 9.75  ? 93  GLU B CD  1 
ATOM 4737 O OE1 . GLU B 1 109 ? 162.667 133.134 200.262 1.00 9.75  ? 93  GLU B OE1 1 
ATOM 4738 O OE2 . GLU B 1 109 ? 161.567 135.000 200.623 1.00 9.75  ? 93  GLU B OE2 1 
ATOM 4739 N N   . SER B 1 110 ? 163.371 139.676 199.354 1.00 8.28  ? 94  SER B N   1 
ATOM 4740 C CA  . SER B 1 110 ? 162.728 140.967 199.125 1.00 8.28  ? 94  SER B CA  1 
ATOM 4741 C C   . SER B 1 110 ? 163.709 142.000 198.583 1.00 8.28  ? 94  SER B C   1 
ATOM 4742 O O   . SER B 1 110 ? 163.359 142.784 197.694 1.00 8.28  ? 94  SER B O   1 
ATOM 4743 C CB  . SER B 1 110 ? 162.084 141.471 200.416 1.00 8.28  ? 94  SER B CB  1 
ATOM 4744 O OG  . SER B 1 110 ? 161.013 140.633 200.813 1.00 8.28  ? 94  SER B OG  1 
ATOM 4745 N N   . VAL B 1 111 ? 164.936 142.023 199.108 1.00 4.33  ? 95  VAL B N   1 
ATOM 4746 C CA  . VAL B 1 111 ? 165.887 143.059 198.714 1.00 4.33  ? 95  VAL B CA  1 
ATOM 4747 C C   . VAL B 1 111 ? 166.268 142.912 197.246 1.00 4.33  ? 95  VAL B C   1 
ATOM 4748 O O   . VAL B 1 111 ? 166.448 143.909 196.537 1.00 4.33  ? 95  VAL B O   1 
ATOM 4749 C CB  . VAL B 1 111 ? 167.122 143.033 199.633 1.00 4.33  ? 95  VAL B CB  1 
ATOM 4750 C CG1 . VAL B 1 111 ? 167.715 141.640 199.698 1.00 4.33  ? 95  VAL B CG1 1 
ATOM 4751 C CG2 . VAL B 1 111 ? 168.161 144.036 199.162 1.00 4.33  ? 95  VAL B CG2 1 
ATOM 4752 N N   . PHE B 1 112 ? 166.390 141.674 196.760 1.00 3.51  ? 96  PHE B N   1 
ATOM 4753 C CA  . PHE B 1 112 ? 166.779 141.475 195.368 1.00 3.51  ? 96  PHE B CA  1 
ATOM 4754 C C   . PHE B 1 112 ? 165.682 141.924 194.411 1.00 3.51  ? 96  PHE B C   1 
ATOM 4755 O O   . PHE B 1 112 ? 165.973 142.420 193.317 1.00 3.51  ? 96  PHE B O   1 
ATOM 4756 C CB  . PHE B 1 112 ? 167.138 140.014 195.112 1.00 3.51  ? 96  PHE B CB  1 
ATOM 4757 C CG  . PHE B 1 112 ? 167.825 139.792 193.798 1.00 3.51  ? 96  PHE B CG  1 
ATOM 4758 C CD1 . PHE B 1 112 ? 169.160 140.113 193.638 1.00 3.51  ? 96  PHE B CD1 1 
ATOM 4759 C CD2 . PHE B 1 112 ? 167.131 139.277 192.718 1.00 3.51  ? 96  PHE B CD2 1 
ATOM 4760 C CE1 . PHE B 1 112 ? 169.792 139.917 192.428 1.00 3.51  ? 96  PHE B CE1 1 
ATOM 4761 C CE2 . PHE B 1 112 ? 167.758 139.079 191.506 1.00 3.51  ? 96  PHE B CE2 1 
ATOM 4762 C CZ  . PHE B 1 112 ? 169.090 139.399 191.361 1.00 3.51  ? 96  PHE B CZ  1 
ATOM 4763 N N   . GLN B 1 113 ? 164.417 141.750 194.796 1.00 2.59  ? 97  GLN B N   1 
ATOM 4764 C CA  . GLN B 1 113 ? 163.329 142.196 193.934 1.00 2.59  ? 97  GLN B CA  1 
ATOM 4765 C C   . GLN B 1 113 ? 163.353 143.708 193.763 1.00 2.59  ? 97  GLN B C   1 
ATOM 4766 O O   . GLN B 1 113 ? 162.989 144.226 192.701 1.00 2.59  ? 97  GLN B O   1 
ATOM 4767 C CB  . GLN B 1 113 ? 161.984 141.740 194.495 1.00 2.59  ? 97  GLN B CB  1 
ATOM 4768 C CG  . GLN B 1 113 ? 160.818 141.962 193.546 1.00 2.59  ? 97  GLN B CG  1 
ATOM 4769 C CD  . GLN B 1 113 ? 159.485 141.584 194.160 1.00 2.59  ? 97  GLN B CD  1 
ATOM 4770 O OE1 . GLN B 1 113 ? 159.387 141.349 195.364 1.00 2.59  ? 97  GLN B OE1 1 
ATOM 4771 N NE2 . GLN B 1 113 ? 158.449 141.523 193.331 1.00 2.59  ? 97  GLN B NE2 1 
ATOM 4772 N N   . LEU B 1 114 ? 163.774 144.436 194.799 1.00 1.85  ? 98  LEU B N   1 
ATOM 4773 C CA  . LEU B 1 114 ? 163.919 145.881 194.682 1.00 1.85  ? 98  LEU B CA  1 
ATOM 4774 C C   . LEU B 1 114 ? 165.158 146.288 193.897 1.00 1.85  ? 98  LEU B C   1 
ATOM 4775 O O   . LEU B 1 114 ? 165.232 147.437 193.449 1.00 1.85  ? 98  LEU B O   1 
ATOM 4776 C CB  . LEU B 1 114 ? 163.953 146.527 196.066 1.00 1.85  ? 98  LEU B CB  1 
ATOM 4777 C CG  . LEU B 1 114 ? 162.610 146.539 196.793 1.00 1.85  ? 98  LEU B CG  1 
ATOM 4778 C CD1 . LEU B 1 114 ? 162.697 147.383 198.042 1.00 1.85  ? 98  LEU B CD1 1 
ATOM 4779 C CD2 . LEU B 1 114 ? 161.508 147.043 195.880 1.00 1.85  ? 98  LEU B CD2 1 
ATOM 4780 N N   . LEU B 1 115 ? 166.129 145.391 193.726 1.00 1.22  ? 99  LEU B N   1 
ATOM 4781 C CA  . LEU B 1 115 ? 167.259 145.673 192.851 1.00 1.22  ? 99  LEU B CA  1 
ATOM 4782 C C   . LEU B 1 115 ? 166.909 145.502 191.382 1.00 1.22  ? 99  LEU B C   1 
ATOM 4783 O O   . LEU B 1 115 ? 167.397 146.269 190.545 1.00 1.22  ? 99  LEU B O   1 
ATOM 4784 C CB  . LEU B 1 115 ? 168.449 144.776 193.200 1.00 1.22  ? 99  LEU B CB  1 
ATOM 4785 C CG  . LEU B 1 115 ? 169.222 145.155 194.462 1.00 1.22  ? 99  LEU B CG  1 
ATOM 4786 C CD1 . LEU B 1 115 ? 170.541 144.415 194.502 1.00 1.22  ? 99  LEU B CD1 1 
ATOM 4787 C CD2 . LEU B 1 115 ? 169.451 146.653 194.521 1.00 1.22  ? 99  LEU B CD2 1 
ATOM 4788 N N   . VAL B 1 116 ? 166.075 144.514 191.050 1.00 1.15  ? 100 VAL B N   1 
ATOM 4789 C CA  . VAL B 1 116 ? 165.570 144.401 189.686 1.00 1.15  ? 100 VAL B CA  1 
ATOM 4790 C C   . VAL B 1 116 ? 164.757 145.637 189.327 1.00 1.15  ? 100 VAL B C   1 
ATOM 4791 O O   . VAL B 1 116 ? 164.815 146.132 188.195 1.00 1.15  ? 100 VAL B O   1 
ATOM 4792 C CB  . VAL B 1 116 ? 164.751 143.107 189.523 1.00 1.15  ? 100 VAL B CB  1 
ATOM 4793 C CG1 . VAL B 1 116 ? 163.904 143.159 188.262 1.00 1.15  ? 100 VAL B CG1 1 
ATOM 4794 C CG2 . VAL B 1 116 ? 165.677 141.903 189.492 1.00 1.15  ? 100 VAL B CG2 1 
ATOM 4795 N N   . ASP B 1 117 ? 164.001 146.169 190.290 1.00 1.16  ? 101 ASP B N   1 
ATOM 4796 C CA  . ASP B 1 117 ? 163.268 147.408 190.056 1.00 1.16  ? 101 ASP B CA  1 
ATOM 4797 C C   . ASP B 1 117 ? 164.206 148.577 189.790 1.00 1.16  ? 101 ASP B C   1 
ATOM 4798 O O   . ASP B 1 117 ? 163.802 149.561 189.161 1.00 1.16  ? 101 ASP B O   1 
ATOM 4799 C CB  . ASP B 1 117 ? 162.364 147.721 191.247 1.00 1.16  ? 101 ASP B CB  1 
ATOM 4800 C CG  . ASP B 1 117 ? 160.936 147.272 191.027 1.00 1.16  ? 101 ASP B CG  1 
ATOM 4801 O OD1 . ASP B 1 117 ? 160.626 146.806 189.912 1.00 1.16  ? 101 ASP B OD1 1 
ATOM 4802 O OD2 . ASP B 1 117 ? 160.124 147.385 191.969 1.00 1.16  ? 101 ASP B OD2 1 
ATOM 4803 N N   . TYR B 1 118 ? 165.453 148.498 190.256 1.00 1.21  ? 102 TYR B N   1 
ATOM 4804 C CA  . TYR B 1 118 ? 166.372 149.613 190.060 1.00 1.21  ? 102 TYR B CA  1 
ATOM 4805 C C   . TYR B 1 118 ? 167.267 149.442 188.838 1.00 1.21  ? 102 TYR B C   1 
ATOM 4806 O O   . TYR B 1 118 ? 167.498 150.413 188.110 1.00 1.21  ? 102 TYR B O   1 
ATOM 4807 C CB  . TYR B 1 118 ? 167.251 149.820 191.292 1.00 1.21  ? 102 TYR B CB  1 
ATOM 4808 C CG  . TYR B 1 118 ? 168.326 150.841 191.030 1.00 1.21  ? 102 TYR B CG  1 
ATOM 4809 C CD1 . TYR B 1 118 ? 168.004 152.175 190.838 1.00 1.21  ? 102 TYR B CD1 1 
ATOM 4810 C CD2 . TYR B 1 118 ? 169.654 150.468 190.933 1.00 1.21  ? 102 TYR B CD2 1 
ATOM 4811 C CE1 . TYR B 1 118 ? 168.977 153.111 190.582 1.00 1.21  ? 102 TYR B CE1 1 
ATOM 4812 C CE2 . TYR B 1 118 ? 170.636 151.397 190.677 1.00 1.21  ? 102 TYR B CE2 1 
ATOM 4813 C CZ  . TYR B 1 118 ? 170.291 152.716 190.502 1.00 1.21  ? 102 TYR B CZ  1 
ATOM 4814 O OH  . TYR B 1 118 ? 171.269 153.644 190.245 1.00 1.21  ? 102 TYR B OH  1 
ATOM 4815 N N   . ILE B 1 119 ? 167.805 148.241 188.611 1.00 1.87  ? 103 ILE B N   1 
ATOM 4816 C CA  . ILE B 1 119 ? 168.594 148.007 187.404 1.00 1.87  ? 103 ILE B CA  1 
ATOM 4817 C C   . ILE B 1 119 ? 167.736 148.242 186.170 1.00 1.87  ? 103 ILE B C   1 
ATOM 4818 O O   . ILE B 1 119 ? 168.175 148.853 185.189 1.00 1.87  ? 103 ILE B O   1 
ATOM 4819 C CB  . ILE B 1 119 ? 169.193 146.589 187.421 1.00 1.87  ? 103 ILE B CB  1 
ATOM 4820 C CG1 . ILE B 1 119 ? 170.005 146.366 188.695 1.00 1.87  ? 103 ILE B CG1 1 
ATOM 4821 C CG2 . ILE B 1 119 ? 170.068 146.365 186.206 1.00 1.87  ? 103 ILE B CG2 1 
ATOM 4822 C CD1 . ILE B 1 119 ? 170.561 144.969 188.822 1.00 1.87  ? 103 ILE B CD1 1 
ATOM 4823 N N   . TYR B 1 120 ? 166.493 147.773 186.212 1.00 2.36  ? 104 TYR B N   1 
ATOM 4824 C CA  . TYR B 1 120 ? 165.462 148.082 185.231 1.00 2.36  ? 104 TYR B CA  1 
ATOM 4825 C C   . TYR B 1 120 ? 164.880 149.454 185.548 1.00 2.36  ? 104 TYR B C   1 
ATOM 4826 O O   . TYR B 1 120 ? 165.554 150.268 186.185 1.00 2.36  ? 104 TYR B O   1 
ATOM 4827 C CB  . TYR B 1 120 ? 164.397 146.987 185.194 1.00 2.36  ? 104 TYR B CB  1 
ATOM 4828 C CG  . TYR B 1 120 ? 164.930 145.691 184.620 1.00 2.36  ? 104 TYR B CG  1 
ATOM 4829 C CD1 . TYR B 1 120 ? 166.180 145.645 184.016 1.00 2.36  ? 104 TYR B CD1 1 
ATOM 4830 C CD2 . TYR B 1 120 ? 164.194 144.519 184.686 1.00 2.36  ? 104 TYR B CD2 1 
ATOM 4831 C CE1 . TYR B 1 120 ? 166.680 144.475 183.494 1.00 2.36  ? 104 TYR B CE1 1 
ATOM 4832 C CE2 . TYR B 1 120 ? 164.688 143.340 184.163 1.00 2.36  ? 104 TYR B CE2 1 
ATOM 4833 C CZ  . TYR B 1 120 ? 165.932 143.326 183.569 1.00 2.36  ? 104 TYR B CZ  1 
ATOM 4834 O OH  . TYR B 1 120 ? 166.432 142.159 183.046 1.00 2.36  ? 104 TYR B OH  1 
ATOM 4835 N N   . HIS B 1 121 ? 163.639 149.711 185.126 1.00 4.43  ? 105 HIS B N   1 
ATOM 4836 C CA  . HIS B 1 121 ? 163.098 151.037 184.828 1.00 4.43  ? 105 HIS B CA  1 
ATOM 4837 C C   . HIS B 1 121 ? 163.718 152.168 185.643 1.00 4.43  ? 105 HIS B C   1 
ATOM 4838 O O   . HIS B 1 121 ? 164.094 153.199 185.078 1.00 4.43  ? 105 HIS B O   1 
ATOM 4839 C CB  . HIS B 1 121 ? 161.586 151.039 185.073 1.00 4.43  ? 105 HIS B CB  1 
ATOM 4840 C CG  . HIS B 1 121 ? 160.939 149.702 184.888 1.00 4.43  ? 105 HIS B CG  1 
ATOM 4841 N ND1 . HIS B 1 121 ? 160.374 149.304 183.697 1.00 4.43  ? 105 HIS B ND1 1 
ATOM 4842 C CD2 . HIS B 1 121 ? 160.756 148.676 185.753 1.00 4.43  ? 105 HIS B CD2 1 
ATOM 4843 C CE1 . HIS B 1 121 ? 159.878 148.087 183.832 1.00 4.43  ? 105 HIS B CE1 1 
ATOM 4844 N NE2 . HIS B 1 121 ? 160.097 147.683 185.071 1.00 4.43  ? 105 HIS B NE2 1 
ATOM 4845 N N   . GLY B 1 122 ? 163.832 152.000 186.957 1.00 3.20  ? 106 GLY B N   1 
ATOM 4846 C CA  . GLY B 1 122 ? 164.589 152.960 187.738 1.00 3.20  ? 106 GLY B CA  1 
ATOM 4847 C C   . GLY B 1 122 ? 163.864 153.575 188.916 1.00 3.20  ? 106 GLY B C   1 
ATOM 4848 O O   . GLY B 1 122 ? 164.279 154.621 189.424 1.00 3.20  ? 106 GLY B O   1 
ATOM 4849 N N   . THR B 1 123 ? 162.784 152.944 189.364 1.00 2.52  ? 107 THR B N   1 
ATOM 4850 C CA  . THR B 1 123 ? 162.041 153.410 190.523 1.00 2.52  ? 107 THR B CA  1 
ATOM 4851 C C   . THR B 1 123 ? 162.180 152.400 191.652 1.00 2.52  ? 107 THR B C   1 
ATOM 4852 O O   . THR B 1 123 ? 161.976 151.198 191.460 1.00 2.52  ? 107 THR B O   1 
ATOM 4853 C CB  . THR B 1 123 ? 160.555 153.626 190.201 1.00 2.52  ? 107 THR B CB  1 
ATOM 4854 O OG1 . THR B 1 123 ? 159.848 152.387 190.340 1.00 2.52  ? 107 THR B OG1 1 
ATOM 4855 C CG2 . THR B 1 123 ? 160.387 154.142 188.781 1.00 2.52  ? 107 THR B CG2 1 
ATOM 4856 N N   . VAL B 1 124 ? 162.530 152.901 192.836 1.00 1.44  ? 108 VAL B N   1 
ATOM 4857 C CA  . VAL B 1 124 ? 162.705 152.058 194.013 1.00 1.44  ? 108 VAL B CA  1 
ATOM 4858 C C   . VAL B 1 124 ? 161.782 152.592 195.097 1.00 1.44  ? 108 VAL B C   1 
ATOM 4859 O O   . VAL B 1 124 ? 161.350 153.744 195.054 1.00 1.44  ? 108 VAL B O   1 
ATOM 4860 C CB  . VAL B 1 124 ? 164.183 152.036 194.480 1.00 1.44  ? 108 VAL B CB  1 
ATOM 4861 C CG1 . VAL B 1 124 ? 164.459 150.807 195.330 1.00 1.44  ? 108 VAL B CG1 1 
ATOM 4862 C CG2 . VAL B 1 124 ? 165.121 152.085 193.290 1.00 1.44  ? 108 VAL B CG2 1 
ATOM 4863 N N   . LYS B 1 125 ? 161.478 151.749 196.079 1.00 1.05  ? 109 LYS B N   1 
ATOM 4864 C CA  . LYS B 1 125 ? 160.540 152.067 197.150 1.00 1.05  ? 109 LYS B CA  1 
ATOM 4865 C C   . LYS B 1 125 ? 161.189 151.832 198.507 1.00 1.05  ? 109 LYS B C   1 
ATOM 4866 O O   . LYS B 1 125 ? 160.664 151.112 199.359 1.00 1.05  ? 109 LYS B O   1 
ATOM 4867 C CB  . LYS B 1 125 ? 159.258 151.253 197.006 1.00 1.05  ? 109 LYS B CB  1 
ATOM 4868 C CG  . LYS B 1 125 ? 158.052 151.872 197.693 1.00 1.05  ? 109 LYS B CG  1 
ATOM 4869 C CD  . LYS B 1 125 ? 156.779 151.111 197.369 1.00 1.05  ? 109 LYS B CD  1 
ATOM 4870 C CE  . LYS B 1 125 ? 155.570 151.772 198.007 1.00 1.05  ? 109 LYS B CE  1 
ATOM 4871 N NZ  . LYS B 1 125 ? 155.306 153.115 197.423 1.00 1.05  ? 109 LYS B NZ  1 
ATOM 4872 N N   . LEU B 1 126 ? 162.371 152.419 198.704 1.00 1.17  ? 110 LEU B N   1 
ATOM 4873 C CA  . LEU B 1 126 ? 163.156 152.259 199.925 1.00 1.17  ? 110 LEU B CA  1 
ATOM 4874 C C   . LEU B 1 126 ? 162.323 152.452 201.187 1.00 1.17  ? 110 LEU B C   1 
ATOM 4875 O O   . LEU B 1 126 ? 161.780 153.536 201.421 1.00 1.17  ? 110 LEU B O   1 
ATOM 4876 C CB  . LEU B 1 126 ? 164.325 153.246 199.932 1.00 1.17  ? 110 LEU B CB  1 
ATOM 4877 C CG  . LEU B 1 126 ? 165.159 153.345 198.656 1.00 1.17  ? 110 LEU B CG  1 
ATOM 4878 C CD1 . LEU B 1 126 ? 165.860 154.687 198.587 1.00 1.17  ? 110 LEU B CD1 1 
ATOM 4879 C CD2 . LEU B 1 126 ? 166.166 152.214 198.594 1.00 1.17  ? 110 LEU B CD2 1 
ATOM 4880 N N   . ARG B 1 127 ? 162.219 151.407 202.002 1.00 2.13  ? 111 ARG B N   1 
ATOM 4881 C CA  . ARG B 1 127 ? 161.491 151.469 203.258 1.00 2.13  ? 111 ARG B CA  1 
ATOM 4882 C C   . ARG B 1 127 ? 162.468 151.412 204.430 1.00 2.13  ? 111 ARG B C   1 
ATOM 4883 O O   . ARG B 1 127 ? 163.684 151.308 204.257 1.00 2.13  ? 111 ARG B O   1 
ATOM 4884 C CB  . ARG B 1 127 ? 160.465 150.339 203.336 1.00 2.13  ? 111 ARG B CB  1 
ATOM 4885 C CG  . ARG B 1 127 ? 159.474 150.324 202.183 1.00 2.13  ? 111 ARG B CG  1 
ATOM 4886 C CD  . ARG B 1 127 ? 158.119 149.764 202.607 1.00 2.13  ? 111 ARG B CD  1 
ATOM 4887 N NE  . ARG B 1 127 ? 158.215 148.489 203.312 1.00 2.13  ? 111 ARG B NE  1 
ATOM 4888 C CZ  . ARG B 1 127 ? 158.726 147.373 202.806 1.00 2.13  ? 111 ARG B CZ  1 
ATOM 4889 N NH1 . ARG B 1 127 ? 159.159 147.309 201.558 1.00 2.13  ? 111 ARG B NH1 1 
ATOM 4890 N NH2 . ARG B 1 127 ? 158.787 146.285 203.569 1.00 2.13  ? 111 ARG B NH2 1 
ATOM 4891 N N   . ALA B 1 128 ? 161.928 151.484 205.646 1.00 3.57  ? 112 ALA B N   1 
ATOM 4892 C CA  . ALA B 1 128 ? 162.739 151.443 206.854 1.00 3.57  ? 112 ALA B CA  1 
ATOM 4893 C C   . ALA B 1 128 ? 162.964 150.033 207.380 1.00 3.57  ? 112 ALA B C   1 
ATOM 4894 O O   . ALA B 1 128 ? 163.966 149.799 208.064 1.00 3.57  ? 112 ALA B O   1 
ATOM 4895 C CB  . ALA B 1 128 ? 162.097 152.297 207.953 1.00 3.57  ? 112 ALA B CB  1 
ATOM 4896 N N   . GLU B 1 129 ? 162.063 149.093 207.084 1.00 5.58  ? 113 GLU B N   1 
ATOM 4897 C CA  . GLU B 1 129 ? 162.268 147.713 207.512 1.00 5.58  ? 113 GLU B CA  1 
ATOM 4898 C C   . GLU B 1 129 ? 163.489 147.104 206.837 1.00 5.58  ? 113 GLU B C   1 
ATOM 4899 O O   . GLU B 1 129 ? 164.306 146.446 207.492 1.00 5.58  ? 113 GLU B O   1 
ATOM 4900 C CB  . GLU B 1 129 ? 161.024 146.879 207.210 1.00 5.58  ? 113 GLU B CB  1 
ATOM 4901 C CG  . GLU B 1 129 ? 161.279 145.379 207.190 1.00 5.58  ? 113 GLU B CG  1 
ATOM 4902 C CD  . GLU B 1 129 ? 160.314 144.635 206.288 1.00 5.58  ? 113 GLU B CD  1 
ATOM 4903 O OE1 . GLU B 1 129 ? 160.418 143.394 206.199 1.00 5.58  ? 113 GLU B OE1 1 
ATOM 4904 O OE2 . GLU B 1 129 ? 159.452 145.292 205.668 1.00 5.58  ? 113 GLU B OE2 1 
ATOM 4905 N N   . GLU B 1 130 ? 163.634 147.317 205.533 1.00 3.37  ? 114 GLU B N   1 
ATOM 4906 C CA  . GLU B 1 130 ? 164.754 146.793 204.759 1.00 3.37  ? 114 GLU B CA  1 
ATOM 4907 C C   . GLU B 1 130 ? 165.562 147.967 204.207 1.00 3.37  ? 114 GLU B C   1 
ATOM 4908 O O   . GLU B 1 130 ? 165.371 148.424 203.083 1.00 3.37  ? 114 GLU B O   1 
ATOM 4909 C CB  . GLU B 1 130 ? 164.224 145.794 203.661 1.00 3.37  ? 114 GLU B CB  1 
ATOM 4910 C CG  . GLU B 1 130 ? 163.081 146.294 202.769 1.00 3.37  ? 114 GLU B CG  1 
ATOM 4911 C CD  . GLU B 1 130 ? 163.531 147.075 201.558 1.00 3.37  ? 114 GLU B CD  1 
ATOM 4912 O OE1 . GLU B 1 130 ? 162.773 147.961 201.115 1.00 3.37  ? 114 GLU B OE1 1 
ATOM 4913 O OE2 . GLU B 1 130 ? 164.630 146.789 201.037 1.00 3.37  ? 114 GLU B OE2 1 
ATOM 4914 N N   . LEU B 1 131 ? 166.478 148.467 205.034 1.00 2.20  ? 115 LEU B N   1 
ATOM 4915 C CA  . LEU B 1 131 ? 167.367 149.551 204.640 1.00 2.20  ? 115 LEU B CA  1 
ATOM 4916 C C   . LEU B 1 131 ? 168.838 149.254 204.873 1.00 2.20  ? 115 LEU B C   1 
ATOM 4917 O O   . LEU B 1 131 ? 169.675 149.786 204.135 1.00 2.20  ? 115 LEU B O   1 
ATOM 4918 C CB  . LEU B 1 131 ? 166.998 150.847 205.376 1.00 2.20  ? 115 LEU B CB  1 
ATOM 4919 C CG  . LEU B 1 131 ? 167.738 152.110 204.935 1.00 2.20  ? 115 LEU B CG  1 
ATOM 4920 C CD1 . LEU B 1 131 ? 167.649 152.276 203.432 1.00 2.20  ? 115 LEU B CD1 1 
ATOM 4921 C CD2 . LEU B 1 131 ? 167.173 153.327 205.641 1.00 2.20  ? 115 LEU B CD2 1 
ATOM 4922 N N   . GLN B 1 132 ? 169.188 148.430 205.857 1.00 1.95  ? 116 GLN B N   1 
ATOM 4923 C CA  . GLN B 1 132 ? 170.578 148.042 206.043 1.00 1.95  ? 116 GLN B CA  1 
ATOM 4924 C C   . GLN B 1 132 ? 170.977 146.870 205.161 1.00 1.95  ? 116 GLN B C   1 
ATOM 4925 O O   . GLN B 1 132 ? 172.145 146.771 204.769 1.00 1.95  ? 116 GLN B O   1 
ATOM 4926 C CB  . GLN B 1 132 ? 170.836 147.696 207.510 1.00 1.95  ? 116 GLN B CB  1 
ATOM 4927 C CG  . GLN B 1 132 ? 170.804 148.901 208.428 1.00 1.95  ? 116 GLN B CG  1 
ATOM 4928 C CD  . GLN B 1 132 ? 171.360 148.602 209.801 1.00 1.95  ? 116 GLN B CD  1 
ATOM 4929 O OE1 . GLN B 1 132 ? 171.865 147.509 210.055 1.00 1.95  ? 116 GLN B OE1 1 
ATOM 4930 N NE2 . GLN B 1 132 ? 171.268 149.575 210.699 1.00 1.95  ? 116 GLN B NE2 1 
ATOM 4931 N N   . GLU B 1 133 ? 170.036 145.978 204.839 1.00 1.38  ? 117 GLU B N   1 
ATOM 4932 C CA  . GLU B 1 133 ? 170.349 144.879 203.933 1.00 1.38  ? 117 GLU B CA  1 
ATOM 4933 C C   . GLU B 1 133 ? 170.586 145.386 202.517 1.00 1.38  ? 117 GLU B C   1 
ATOM 4934 O O   . GLU B 1 133 ? 171.493 144.911 201.826 1.00 1.38  ? 117 GLU B O   1 
ATOM 4935 C CB  . GLU B 1 133 ? 169.229 143.840 203.950 1.00 1.38  ? 117 GLU B CB  1 
ATOM 4936 C CG  . GLU B 1 133 ? 168.912 143.293 205.329 1.00 1.38  ? 117 GLU B CG  1 
ATOM 4937 C CD  . GLU B 1 133 ? 167.431 143.340 205.648 1.00 1.38  ? 117 GLU B CD  1 
ATOM 4938 O OE1 . GLU B 1 133 ? 166.635 143.645 204.735 1.00 1.38  ? 117 GLU B OE1 1 
ATOM 4939 O OE2 . GLU B 1 133 ? 167.063 143.075 206.811 1.00 1.38  ? 117 GLU B OE2 1 
ATOM 4940 N N   . ILE B 1 134 ? 169.783 146.355 202.069 1.00 0.80  ? 118 ILE B N   1 
ATOM 4941 C CA  . ILE B 1 134 ? 169.987 146.953 200.755 1.00 0.80  ? 118 ILE B CA  1 
ATOM 4942 C C   . ILE B 1 134 ? 171.192 147.880 200.738 1.00 0.80  ? 118 ILE B C   1 
ATOM 4943 O O   . ILE B 1 134 ? 171.712 148.195 199.663 1.00 0.80  ? 118 ILE B O   1 
ATOM 4944 C CB  . ILE B 1 134 ? 168.699 147.687 200.321 1.00 0.80  ? 118 ILE B CB  1 
ATOM 4945 C CG1 . ILE B 1 134 ? 168.822 148.266 198.913 1.00 0.80  ? 118 ILE B CG1 1 
ATOM 4946 C CG2 . ILE B 1 134 ? 168.364 148.794 201.291 1.00 0.80  ? 118 ILE B CG2 1 
ATOM 4947 C CD1 . ILE B 1 134 ? 167.491 148.494 198.240 1.00 0.80  ? 118 ILE B CD1 1 
ATOM 4948 N N   . TYR B 1 135 ? 171.674 148.300 201.908 1.00 0.76  ? 119 TYR B N   1 
ATOM 4949 C CA  . TYR B 1 135 ? 172.883 149.113 201.969 1.00 0.76  ? 119 TYR B CA  1 
ATOM 4950 C C   . TYR B 1 135 ? 174.125 148.281 201.681 1.00 0.76  ? 119 TYR B C   1 
ATOM 4951 O O   . TYR B 1 135 ? 174.992 148.695 200.905 1.00 0.76  ? 119 TYR B O   1 
ATOM 4952 C CB  . TYR B 1 135 ? 172.988 149.781 203.341 1.00 0.76  ? 119 TYR B CB  1 
ATOM 4953 C CG  . TYR B 1 135 ? 174.143 150.748 203.491 1.00 0.76  ? 119 TYR B CG  1 
ATOM 4954 C CD1 . TYR B 1 135 ? 175.398 150.307 203.888 1.00 0.76  ? 119 TYR B CD1 1 
ATOM 4955 C CD2 . TYR B 1 135 ? 173.973 152.102 203.250 1.00 0.76  ? 119 TYR B CD2 1 
ATOM 4956 C CE1 . TYR B 1 135 ? 176.450 151.186 204.033 1.00 0.76  ? 119 TYR B CE1 1 
ATOM 4957 C CE2 . TYR B 1 135 ? 175.021 152.988 203.393 1.00 0.76  ? 119 TYR B CE2 1 
ATOM 4958 C CZ  . TYR B 1 135 ? 176.256 152.525 203.786 1.00 0.76  ? 119 TYR B CZ  1 
ATOM 4959 O OH  . TYR B 1 135 ? 177.302 153.406 203.926 1.00 0.76  ? 119 TYR B OH  1 
ATOM 4960 N N   . GLU B 1 136 ? 174.231 147.104 202.302 1.00 0.77  ? 120 GLU B N   1 
ATOM 4961 C CA  . GLU B 1 136 ? 175.393 146.250 202.082 1.00 0.77  ? 120 GLU B CA  1 
ATOM 4962 C C   . GLU B 1 136 ? 175.327 145.543 200.734 1.00 0.77  ? 120 GLU B C   1 
ATOM 4963 O O   . GLU B 1 136 ? 176.351 145.398 200.058 1.00 0.77  ? 120 GLU B O   1 
ATOM 4964 C CB  . GLU B 1 136 ? 175.516 145.226 203.209 1.00 0.77  ? 120 GLU B CB  1 
ATOM 4965 C CG  . GLU B 1 136 ? 175.779 145.832 204.574 1.00 0.77  ? 120 GLU B CG  1 
ATOM 4966 C CD  . GLU B 1 136 ? 175.297 144.945 205.705 1.00 0.77  ? 120 GLU B CD  1 
ATOM 4967 O OE1 . GLU B 1 136 ? 174.641 143.922 205.419 1.00 0.77  ? 120 GLU B OE1 1 
ATOM 4968 O OE2 . GLU B 1 136 ? 175.573 145.269 206.878 1.00 0.77  ? 120 GLU B OE2 1 
ATOM 4969 N N   . VAL B 1 137 ? 174.137 145.089 200.334 1.00 0.45  ? 121 VAL B N   1 
ATOM 4970 C CA  . VAL B 1 137 ? 174.002 144.367 199.073 1.00 0.45  ? 121 VAL B CA  1 
ATOM 4971 C C   . VAL B 1 137 ? 174.315 145.278 197.893 1.00 0.45  ? 121 VAL B C   1 
ATOM 4972 O O   . VAL B 1 137 ? 175.017 144.882 196.956 1.00 0.45  ? 121 VAL B O   1 
ATOM 4973 C CB  . VAL B 1 137 ? 172.597 143.749 198.962 1.00 0.45  ? 121 VAL B CB  1 
ATOM 4974 C CG1 . VAL B 1 137 ? 172.263 143.437 197.518 1.00 0.45  ? 121 VAL B CG1 1 
ATOM 4975 C CG2 . VAL B 1 137 ? 172.508 142.493 199.811 1.00 0.45  ? 121 VAL B CG2 1 
ATOM 4976 N N   . SER B 1 138 ? 173.812 146.515 197.920 1.00 0.52  ? 122 SER B N   1 
ATOM 4977 C CA  . SER B 1 138 ? 174.088 147.448 196.834 1.00 0.52  ? 122 SER B CA  1 
ATOM 4978 C C   . SER B 1 138 ? 175.546 147.884 196.797 1.00 0.52  ? 122 SER B C   1 
ATOM 4979 O O   . SER B 1 138 ? 175.983 148.449 195.790 1.00 0.52  ? 122 SER B O   1 
ATOM 4980 C CB  . SER B 1 138 ? 173.187 148.676 196.945 1.00 0.52  ? 122 SER B CB  1 
ATOM 4981 O OG  . SER B 1 138 ? 173.400 149.558 195.859 1.00 0.52  ? 122 SER B OG  1 
ATOM 4982 N N   . ASP B 1 139 ? 176.301 147.649 197.868 1.00 0.69  ? 123 ASP B N   1 
ATOM 4983 C CA  . ASP B 1 139 ? 177.736 147.900 197.849 1.00 0.69  ? 123 ASP B CA  1 
ATOM 4984 C C   . ASP B 1 139 ? 178.531 146.686 197.395 1.00 0.69  ? 123 ASP B C   1 
ATOM 4985 O O   . ASP B 1 139 ? 179.632 146.841 196.856 1.00 0.69  ? 123 ASP B O   1 
ATOM 4986 C CB  . ASP B 1 139 ? 178.219 148.334 199.234 1.00 0.69  ? 123 ASP B CB  1 
ATOM 4987 C CG  . ASP B 1 139 ? 179.653 148.813 199.223 1.00 0.69  ? 123 ASP B CG  1 
ATOM 4988 O OD1 . ASP B 1 139 ? 180.564 147.970 199.356 1.00 0.69  ? 123 ASP B OD1 1 
ATOM 4989 O OD2 . ASP B 1 139 ? 179.872 150.034 199.080 1.00 0.69  ? 123 ASP B OD2 1 
ATOM 4990 N N   . MET B 1 140 ? 177.999 145.480 197.607 1.00 0.66  ? 124 MET B N   1 
ATOM 4991 C CA  . MET B 1 140 ? 178.669 144.279 197.120 1.00 0.66  ? 124 MET B CA  1 
ATOM 4992 C C   . MET B 1 140 ? 178.590 144.183 195.602 1.00 0.66  ? 124 MET B C   1 
ATOM 4993 O O   . MET B 1 140 ? 179.507 143.662 194.958 1.00 0.66  ? 124 MET B O   1 
ATOM 4994 C CB  . MET B 1 140 ? 178.058 143.040 197.772 1.00 0.66  ? 124 MET B CB  1 
ATOM 4995 C CG  . MET B 1 140 ? 178.789 141.746 197.460 1.00 0.66  ? 124 MET B CG  1 
ATOM 4996 S SD  . MET B 1 140 ? 178.048 140.298 198.240 1.00 0.66  ? 124 MET B SD  1 
ATOM 4997 C CE  . MET B 1 140 ? 177.026 141.058 199.500 1.00 0.66  ? 124 MET B CE  1 
ATOM 4998 N N   . TYR B 1 141 ? 177.506 144.683 195.014 1.00 0.91  ? 125 TYR B N   1 
ATOM 4999 C CA  . TYR B 1 141 ? 177.312 144.655 193.571 1.00 0.91  ? 125 TYR B CA  1 
ATOM 5000 C C   . TYR B 1 141 ? 177.878 145.882 192.872 1.00 0.91  ? 125 TYR B C   1 
ATOM 5001 O O   . TYR B 1 141 ? 177.680 146.031 191.663 1.00 0.91  ? 125 TYR B O   1 
ATOM 5002 C CB  . TYR B 1 141 ? 175.823 144.515 193.240 1.00 0.91  ? 125 TYR B CB  1 
ATOM 5003 C CG  . TYR B 1 141 ? 175.226 143.189 193.652 1.00 0.91  ? 125 TYR B CG  1 
ATOM 5004 C CD1 . TYR B 1 141 ? 176.037 142.108 193.966 1.00 0.91  ? 125 TYR B CD1 1 
ATOM 5005 C CD2 . TYR B 1 141 ? 173.851 143.015 193.719 1.00 0.91  ? 125 TYR B CD2 1 
ATOM 5006 C CE1 . TYR B 1 141 ? 175.499 140.895 194.340 1.00 0.91  ? 125 TYR B CE1 1 
ATOM 5007 C CE2 . TYR B 1 141 ? 173.303 141.804 194.093 1.00 0.91  ? 125 TYR B CE2 1 
ATOM 5008 C CZ  . TYR B 1 141 ? 174.133 140.748 194.402 1.00 0.91  ? 125 TYR B CZ  1 
ATOM 5009 O OH  . TYR B 1 141 ? 173.596 139.539 194.775 1.00 0.91  ? 125 TYR B OH  1 
ATOM 5010 N N   . GLN B 1 142 ? 178.564 146.762 193.605 1.00 1.38  ? 126 GLN B N   1 
ATOM 5011 C CA  . GLN B 1 142 ? 179.210 147.946 193.036 1.00 1.38  ? 126 GLN B CA  1 
ATOM 5012 C C   . GLN B 1 142 ? 178.209 148.846 192.317 1.00 1.38  ? 126 GLN B C   1 
ATOM 5013 O O   . GLN B 1 142 ? 178.514 149.445 191.284 1.00 1.38  ? 126 GLN B O   1 
ATOM 5014 C CB  . GLN B 1 142 ? 180.357 147.557 192.100 1.00 1.38  ? 126 GLN B CB  1 
ATOM 5015 C CG  . GLN B 1 142 ? 181.332 146.556 192.692 1.00 1.38  ? 126 GLN B CG  1 
ATOM 5016 C CD  . GLN B 1 142 ? 182.398 147.215 193.542 1.00 1.38  ? 126 GLN B CD  1 
ATOM 5017 O OE1 . GLN B 1 142 ? 182.478 148.441 193.616 1.00 1.38  ? 126 GLN B OE1 1 
ATOM 5018 N NE2 . GLN B 1 142 ? 183.227 146.403 194.186 1.00 1.38  ? 126 GLN B NE2 1 
ATOM 5019 N N   . LEU B 1 143 ? 177.002 148.945 192.867 1.00 0.86  ? 127 LEU B N   1 
ATOM 5020 C CA  . LEU B 1 143 ? 175.997 149.857 192.335 1.00 0.86  ? 127 LEU B CA  1 
ATOM 5021 C C   . LEU B 1 143 ? 176.310 151.266 192.824 1.00 0.86  ? 127 LEU B C   1 
ATOM 5022 O O   . LEU B 1 143 ? 176.318 151.522 194.032 1.00 0.86  ? 127 LEU B O   1 
ATOM 5023 C CB  . LEU B 1 143 ? 174.600 149.419 192.764 1.00 0.86  ? 127 LEU B CB  1 
ATOM 5024 C CG  . LEU B 1 143 ? 173.725 148.792 191.677 1.00 0.86  ? 127 LEU B CG  1 
ATOM 5025 C CD1 . LEU B 1 143 ? 174.279 147.446 191.257 1.00 0.86  ? 127 LEU B CD1 1 
ATOM 5026 C CD2 . LEU B 1 143 ? 172.309 148.633 192.179 1.00 0.86  ? 127 LEU B CD2 1 
ATOM 5027 N N   . THR B 1 144 ? 176.571 152.177 191.887 1.00 1.20  ? 128 THR B N   1 
ATOM 5028 C CA  . THR B 1 144 ? 177.117 153.481 192.251 1.00 1.20  ? 128 THR B CA  1 
ATOM 5029 C C   . THR B 1 144 ? 176.030 154.456 192.697 1.00 1.20  ? 128 THR B C   1 
ATOM 5030 O O   . THR B 1 144 ? 176.125 155.053 193.774 1.00 1.20  ? 128 THR B O   1 
ATOM 5031 C CB  . THR B 1 144 ? 177.924 154.057 191.080 1.00 1.20  ? 128 THR B CB  1 
ATOM 5032 O OG1 . THR B 1 144 ? 178.181 155.449 191.308 1.00 1.20  ? 128 THR B OG1 1 
ATOM 5033 C CG2 . THR B 1 144 ? 177.192 153.871 189.754 1.00 1.20  ? 128 THR B CG2 1 
ATOM 5034 N N   . SER B 1 145 ? 174.988 154.632 191.882 1.00 1.22  ? 129 SER B N   1 
ATOM 5035 C CA  . SER B 1 145 ? 174.000 155.663 192.183 1.00 1.22  ? 129 SER B CA  1 
ATOM 5036 C C   . SER B 1 145 ? 173.087 155.261 193.333 1.00 1.22  ? 129 SER B C   1 
ATOM 5037 O O   . SER B 1 145 ? 172.588 156.131 194.055 1.00 1.22  ? 129 SER B O   1 
ATOM 5038 C CB  . SER B 1 145 ? 173.177 155.986 190.938 1.00 1.22  ? 129 SER B CB  1 
ATOM 5039 O OG  . SER B 1 145 ? 172.352 157.117 191.156 1.00 1.22  ? 129 SER B OG  1 
ATOM 5040 N N   . LEU B 1 146 ? 172.848 153.961 193.518 1.00 0.92  ? 130 LEU B N   1 
ATOM 5041 C CA  . LEU B 1 146 ? 172.040 153.530 194.654 1.00 0.92  ? 130 LEU B CA  1 
ATOM 5042 C C   . LEU B 1 146 ? 172.783 153.722 195.968 1.00 0.92  ? 130 LEU B C   1 
ATOM 5043 O O   . LEU B 1 146 ? 172.153 153.962 197.004 1.00 0.92  ? 130 LEU B O   1 
ATOM 5044 C CB  . LEU B 1 146 ? 171.621 152.070 194.491 1.00 0.92  ? 130 LEU B CB  1 
ATOM 5045 C CG  . LEU B 1 146 ? 170.636 151.550 195.539 1.00 0.92  ? 130 LEU B CG  1 
ATOM 5046 C CD1 . LEU B 1 146 ? 169.445 152.482 195.655 1.00 0.92  ? 130 LEU B CD1 1 
ATOM 5047 C CD2 . LEU B 1 146 ? 170.182 150.146 195.200 1.00 0.92  ? 130 LEU B CD2 1 
ATOM 5048 N N   . PHE B 1 147 ? 174.109 153.627 195.950 1.00 1.08  ? 131 PHE B N   1 
ATOM 5049 C CA  . PHE B 1 147 ? 174.906 153.894 197.146 1.00 1.08  ? 131 PHE B CA  1 
ATOM 5050 C C   . PHE B 1 147 ? 175.244 155.378 197.257 1.00 1.08  ? 131 PHE B C   1 
ATOM 5051 O O   . PHE B 1 147 ? 176.370 155.773 197.552 1.00 1.08  ? 131 PHE B O   1 
ATOM 5052 C CB  . PHE B 1 147 ? 176.168 153.044 197.111 1.00 1.08  ? 131 PHE B CB  1 
ATOM 5053 C CG  . PHE B 1 147 ? 176.801 152.837 198.450 1.00 1.08  ? 131 PHE B CG  1 
ATOM 5054 C CD1 . PHE B 1 147 ? 176.186 152.050 199.402 1.00 1.08  ? 131 PHE B CD1 1 
ATOM 5055 C CD2 . PHE B 1 147 ? 178.020 153.415 198.749 1.00 1.08  ? 131 PHE B CD2 1 
ATOM 5056 C CE1 . PHE B 1 147 ? 176.770 151.851 200.632 1.00 1.08  ? 131 PHE B CE1 1 
ATOM 5057 C CE2 . PHE B 1 147 ? 178.608 153.221 199.978 1.00 1.08  ? 131 PHE B CE2 1 
ATOM 5058 C CZ  . PHE B 1 147 ? 177.983 152.438 200.922 1.00 1.08  ? 131 PHE B CZ  1 
ATOM 5059 N N   . GLU B 1 148 ? 174.233 156.210 197.018 1.00 2.14  ? 132 GLU B N   1 
ATOM 5060 C CA  . GLU B 1 148 ? 174.292 157.642 197.291 1.00 2.14  ? 132 GLU B CA  1 
ATOM 5061 C C   . GLU B 1 148 ? 173.005 158.188 197.880 1.00 2.14  ? 132 GLU B C   1 
ATOM 5062 O O   . GLU B 1 148 ? 173.011 159.315 198.388 1.00 2.14  ? 132 GLU B O   1 
ATOM 5063 C CB  . GLU B 1 148 ? 174.632 158.427 196.018 1.00 2.14  ? 132 GLU B CB  1 
ATOM 5064 C CG  . GLU B 1 148 ? 176.104 158.379 195.638 1.00 2.14  ? 132 GLU B CG  1 
ATOM 5065 C CD  . GLU B 1 148 ? 176.379 158.997 194.282 1.00 2.14  ? 132 GLU B CD  1 
ATOM 5066 O OE1 . GLU B 1 148 ? 175.426 159.500 193.651 1.00 2.14  ? 132 GLU B OE1 1 
ATOM 5067 O OE2 . GLU B 1 148 ? 177.549 158.977 193.846 1.00 2.14  ? 132 GLU B OE2 1 
ATOM 5068 N N   . GLU B 1 149 ? 171.903 157.446 197.817 1.00 1.87  ? 133 GLU B N   1 
ATOM 5069 C CA  . GLU B 1 149 ? 170.665 157.774 198.505 1.00 1.87  ? 133 GLU B CA  1 
ATOM 5070 C C   . GLU B 1 149 ? 170.334 156.793 199.616 1.00 1.87  ? 133 GLU B C   1 
ATOM 5071 O O   . GLU B 1 149 ? 169.695 157.182 200.595 1.00 1.87  ? 133 GLU B O   1 
ATOM 5072 C CB  . GLU B 1 149 ? 169.498 157.822 197.505 1.00 1.87  ? 133 GLU B CB  1 
ATOM 5073 C CG  . GLU B 1 149 ? 168.141 158.184 198.100 1.00 1.87  ? 133 GLU B CG  1 
ATOM 5074 C CD  . GLU B 1 149 ? 168.067 159.605 198.645 1.00 1.87  ? 133 GLU B CD  1 
ATOM 5075 O OE1 . GLU B 1 149 ? 169.058 160.358 198.536 1.00 1.87  ? 133 GLU B OE1 1 
ATOM 5076 O OE2 . GLU B 1 149 ? 167.004 159.969 199.192 1.00 1.87  ? 133 GLU B OE2 1 
ATOM 5077 N N   . CYS B 1 150 ? 170.766 155.536 199.497 1.00 1.39  ? 134 CYS B N   1 
ATOM 5078 C CA  . CYS B 1 150 ? 170.662 154.602 200.609 1.00 1.39  ? 134 CYS B CA  1 
ATOM 5079 C C   . CYS B 1 150 ? 171.647 154.935 201.721 1.00 1.39  ? 134 CYS B C   1 
ATOM 5080 O O   . CYS B 1 150 ? 171.448 154.500 202.860 1.00 1.39  ? 134 CYS B O   1 
ATOM 5081 C CB  . CYS B 1 150 ? 170.883 153.173 200.116 1.00 1.39  ? 134 CYS B CB  1 
ATOM 5082 S SG  . CYS B 1 150 ? 170.580 151.897 201.350 1.00 1.39  ? 134 CYS B SG  1 
ATOM 5083 N N   . SER B 1 151 ? 172.703 155.691 201.417 1.00 1.54  ? 135 SER B N   1 
ATOM 5084 C CA  . SER B 1 151 ? 173.577 156.228 202.451 1.00 1.54  ? 135 SER B CA  1 
ATOM 5085 C C   . SER B 1 151 ? 173.089 157.570 202.969 1.00 1.54  ? 135 SER B C   1 
ATOM 5086 O O   . SER B 1 151 ? 173.311 157.892 204.141 1.00 1.54  ? 135 SER B O   1 
ATOM 5087 C CB  . SER B 1 151 ? 175.004 156.379 201.923 1.00 1.54  ? 135 SER B CB  1 
ATOM 5088 O OG  . SER B 1 151 ? 175.106 157.490 201.052 1.00 1.54  ? 135 SER B OG  1 
ATOM 5089 N N   . ARG B 1 152 ? 172.435 158.363 202.117 1.00 1.81  ? 136 ARG B N   1 
ATOM 5090 C CA  . ARG B 1 152 ? 171.782 159.577 202.590 1.00 1.81  ? 136 ARG B CA  1 
ATOM 5091 C C   . ARG B 1 152 ? 170.646 159.252 203.547 1.00 1.81  ? 136 ARG B C   1 
ATOM 5092 O O   . ARG B 1 152 ? 170.427 159.980 204.522 1.00 1.81  ? 136 ARG B O   1 
ATOM 5093 C CB  . ARG B 1 152 ? 171.260 160.393 201.408 1.00 1.81  ? 136 ARG B CB  1 
ATOM 5094 C CG  . ARG B 1 152 ? 171.784 161.815 201.347 1.00 1.81  ? 136 ARG B CG  1 
ATOM 5095 C CD  . ARG B 1 152 ? 173.095 161.895 200.588 1.00 1.81  ? 136 ARG B CD  1 
ATOM 5096 N NE  . ARG B 1 152 ? 173.759 163.177 200.794 1.00 1.81  ? 136 ARG B NE  1 
ATOM 5097 C CZ  . ARG B 1 152 ? 174.957 163.486 200.319 1.00 1.81  ? 136 ARG B CZ  1 
ATOM 5098 N NH1 . ARG B 1 152 ? 175.657 162.628 199.595 1.00 1.81  ? 136 ARG B NH1 1 
ATOM 5099 N NH2 . ARG B 1 152 ? 175.467 164.688 200.576 1.00 1.81  ? 136 ARG B NH2 1 
ATOM 5100 N N   . PHE B 1 153 ? 169.908 158.171 203.280 1.00 1.04  ? 137 PHE B N   1 
ATOM 5101 C CA  . PHE B 1 153 ? 168.848 157.749 204.190 1.00 1.04  ? 137 PHE B CA  1 
ATOM 5102 C C   . PHE B 1 153 ? 169.407 157.441 205.572 1.00 1.04  ? 137 PHE B C   1 
ATOM 5103 O O   . PHE B 1 153 ? 168.862 157.897 206.583 1.00 1.04  ? 137 PHE B O   1 
ATOM 5104 C CB  . PHE B 1 153 ? 168.129 156.529 203.614 1.00 1.04  ? 137 PHE B CB  1 
ATOM 5105 C CG  . PHE B 1 153 ? 166.698 156.387 204.059 1.00 1.04  ? 137 PHE B CG  1 
ATOM 5106 C CD1 . PHE B 1 153 ? 166.286 156.831 205.300 1.00 1.04  ? 137 PHE B CD1 1 
ATOM 5107 C CD2 . PHE B 1 153 ? 165.768 155.786 203.233 1.00 1.04  ? 137 PHE B CD2 1 
ATOM 5108 C CE1 . PHE B 1 153 ? 164.976 156.692 205.702 1.00 1.04  ? 137 PHE B CE1 1 
ATOM 5109 C CE2 . PHE B 1 153 ? 164.458 155.642 203.631 1.00 1.04  ? 137 PHE B CE2 1 
ATOM 5110 C CZ  . PHE B 1 153 ? 164.061 156.097 204.866 1.00 1.04  ? 137 PHE B CZ  1 
ATOM 5111 N N   . LEU B 1 154 ? 170.502 156.681 205.638 1.00 1.16  ? 138 LEU B N   1 
ATOM 5112 C CA  . LEU B 1 154 ? 171.088 156.358 206.934 1.00 1.16  ? 138 LEU B CA  1 
ATOM 5113 C C   . LEU B 1 154 ? 171.664 157.592 207.615 1.00 1.16  ? 138 LEU B C   1 
ATOM 5114 O O   . LEU B 1 154 ? 171.642 157.681 208.845 1.00 1.16  ? 138 LEU B O   1 
ATOM 5115 C CB  . LEU B 1 154 ? 172.160 155.282 206.780 1.00 1.16  ? 138 LEU B CB  1 
ATOM 5116 C CG  . LEU B 1 154 ? 171.621 153.877 206.516 1.00 1.16  ? 138 LEU B CG  1 
ATOM 5117 C CD1 . LEU B 1 154 ? 172.749 152.865 206.506 1.00 1.16  ? 138 LEU B CD1 1 
ATOM 5118 C CD2 . LEU B 1 154 ? 170.582 153.510 207.557 1.00 1.16  ? 138 LEU B CD2 1 
ATOM 5119 N N   . ALA B 1 155 ? 172.165 158.555 206.845 1.00 1.08  ? 139 ALA B N   1 
ATOM 5120 C CA  . ALA B 1 155 ? 172.619 159.814 207.421 1.00 1.08  ? 139 ALA B CA  1 
ATOM 5121 C C   . ALA B 1 155 ? 171.466 160.727 207.813 1.00 1.08  ? 139 ALA B C   1 
ATOM 5122 O O   . ALA B 1 155 ? 171.710 161.875 208.200 1.00 1.08  ? 139 ALA B O   1 
ATOM 5123 C CB  . ALA B 1 155 ? 173.541 160.544 206.442 1.00 1.08  ? 139 ALA B CB  1 
ATOM 5124 N N   . ARG B 1 156 ? 170.225 160.246 207.721 1.00 0.91  ? 140 ARG B N   1 
ATOM 5125 C CA  . ARG B 1 156 ? 169.045 161.051 207.993 1.00 0.91  ? 140 ARG B CA  1 
ATOM 5126 C C   . ARG B 1 156 ? 168.203 160.540 209.152 1.00 0.91  ? 140 ARG B C   1 
ATOM 5127 O O   . ARG B 1 156 ? 167.434 161.320 209.720 1.00 0.91  ? 140 ARG B O   1 
ATOM 5128 C CB  . ARG B 1 156 ? 168.162 161.127 206.738 1.00 0.91  ? 140 ARG B CB  1 
ATOM 5129 C CG  . ARG B 1 156 ? 167.272 162.348 206.660 1.00 0.91  ? 140 ARG B CG  1 
ATOM 5130 C CD  . ARG B 1 156 ? 166.381 162.280 205.435 1.00 0.91  ? 140 ARG B CD  1 
ATOM 5131 N NE  . ARG B 1 156 ? 167.158 162.150 204.210 1.00 0.91  ? 140 ARG B NE  1 
ATOM 5132 C CZ  . ARG B 1 156 ? 166.632 162.015 203.002 1.00 0.91  ? 140 ARG B CZ  1 
ATOM 5133 N NH1 . ARG B 1 156 ? 165.323 161.963 202.821 1.00 0.91  ? 140 ARG B NH1 1 
ATOM 5134 N NH2 . ARG B 1 156 ? 167.438 161.925 201.948 1.00 0.91  ? 140 ARG B NH2 1 
ATOM 5135 N N   . THR B 1 157 ? 168.325 159.267 209.518 1.00 1.28  ? 141 THR B N   1 
ATOM 5136 C CA  . THR B 1 157 ? 167.484 158.661 210.546 1.00 1.28  ? 141 THR B CA  1 
ATOM 5137 C C   . THR B 1 157 ? 168.330 157.922 211.577 1.00 1.28  ? 141 THR B C   1 
ATOM 5138 O O   . THR B 1 157 ? 168.034 156.791 211.968 1.00 1.28  ? 141 THR B O   1 
ATOM 5139 C CB  . THR B 1 157 ? 166.452 157.725 209.920 1.00 1.28  ? 141 THR B CB  1 
ATOM 5140 O OG1 . THR B 1 157 ? 165.768 157.006 210.952 1.00 1.28  ? 141 THR B OG1 1 
ATOM 5141 C CG2 . THR B 1 157 ? 167.121 156.738 208.977 1.00 1.28  ? 141 THR B CG2 1 
ATOM 5142 N N   . VAL B 1 158 ? 169.401 158.558 212.044 1.00 2.22  ? 142 VAL B N   1 
ATOM 5143 C CA  . VAL B 1 158 ? 170.203 158.036 213.146 1.00 2.22  ? 142 VAL B CA  1 
ATOM 5144 C C   . VAL B 1 158 ? 169.672 158.645 214.440 1.00 2.22  ? 142 VAL B C   1 
ATOM 5145 O O   . VAL B 1 158 ? 169.889 159.824 214.737 1.00 2.22  ? 142 VAL B O   1 
ATOM 5146 C CB  . VAL B 1 158 ? 171.701 158.292 212.948 1.00 2.22  ? 142 VAL B CB  1 
ATOM 5147 C CG1 . VAL B 1 158 ? 172.219 157.458 211.810 1.00 2.22  ? 142 VAL B CG1 1 
ATOM 5148 C CG2 . VAL B 1 158 ? 171.964 159.753 212.625 1.00 2.22  ? 142 VAL B CG2 1 
ATOM 5149 N N   . GLN B 1 159 ? 168.951 157.837 215.208 1.00 3.59  ? 143 GLN B N   1 
ATOM 5150 C CA  . GLN B 1 159 ? 168.543 158.215 216.547 1.00 3.59  ? 143 GLN B CA  1 
ATOM 5151 C C   . GLN B 1 159 ? 169.643 157.822 217.529 1.00 3.59  ? 143 GLN B C   1 
ATOM 5152 O O   . GLN B 1 159 ? 170.632 157.182 217.166 1.00 3.59  ? 143 GLN B O   1 
ATOM 5153 C CB  . GLN B 1 159 ? 167.212 157.559 216.905 1.00 3.59  ? 143 GLN B CB  1 
ATOM 5154 C CG  . GLN B 1 159 ? 166.177 157.622 215.796 1.00 3.59  ? 143 GLN B CG  1 
ATOM 5155 C CD  . GLN B 1 159 ? 165.264 156.414 215.788 1.00 3.59  ? 143 GLN B CD  1 
ATOM 5156 O OE1 . GLN B 1 159 ? 165.447 155.488 214.997 1.00 3.59  ? 143 GLN B OE1 1 
ATOM 5157 N NE2 . GLN B 1 159 ? 164.271 156.416 216.670 1.00 3.59  ? 143 GLN B NE2 1 
ATOM 5158 N N   . VAL B 1 160 ? 169.467 158.199 218.796 1.00 4.72  ? 144 VAL B N   1 
ATOM 5159 C CA  . VAL B 1 160 ? 170.484 157.901 219.798 1.00 4.72  ? 144 VAL B CA  1 
ATOM 5160 C C   . VAL B 1 160 ? 170.665 156.397 219.958 1.00 4.72  ? 144 VAL B C   1 
ATOM 5161 O O   . VAL B 1 160 ? 171.793 155.914 220.118 1.00 4.72  ? 144 VAL B O   1 
ATOM 5162 C CB  . VAL B 1 160 ? 170.118 158.576 221.133 1.00 4.72  ? 144 VAL B CB  1 
ATOM 5163 C CG1 . VAL B 1 160 ? 170.700 157.806 222.305 1.00 4.72  ? 144 VAL B CG1 1 
ATOM 5164 C CG2 . VAL B 1 160 ? 170.600 160.013 221.145 1.00 4.72  ? 144 VAL B CG2 1 
ATOM 5165 N N   . GLY B 1 161 ? 169.573 155.631 219.887 1.00 4.58  ? 145 GLY B N   1 
ATOM 5166 C CA  . GLY B 1 161 ? 169.642 154.202 220.128 1.00 4.58  ? 145 GLY B CA  1 
ATOM 5167 C C   . GLY B 1 161 ? 170.392 153.408 219.081 1.00 4.58  ? 145 GLY B C   1 
ATOM 5168 O O   . GLY B 1 161 ? 170.854 152.301 219.377 1.00 4.58  ? 145 GLY B O   1 
ATOM 5169 N N   . ASN B 1 162 ? 170.529 153.939 217.869 1.00 4.57  ? 146 ASN B N   1 
ATOM 5170 C CA  . ASN B 1 162 ? 171.224 153.252 216.787 1.00 4.57  ? 146 ASN B CA  1 
ATOM 5171 C C   . ASN B 1 162 ? 172.301 154.139 216.173 1.00 4.57  ? 146 ASN B C   1 
ATOM 5172 O O   . ASN B 1 162 ? 172.578 154.073 214.974 1.00 4.57  ? 146 ASN B O   1 
ATOM 5173 C CB  . ASN B 1 162 ? 170.240 152.775 215.721 1.00 4.57  ? 146 ASN B CB  1 
ATOM 5174 C CG  . ASN B 1 162 ? 169.574 153.919 214.986 1.00 4.57  ? 146 ASN B CG  1 
ATOM 5175 O OD1 . ASN B 1 162 ? 168.632 154.532 215.488 1.00 4.57  ? 146 ASN B OD1 1 
ATOM 5176 N ND2 . ASN B 1 162 ? 170.060 154.211 213.786 1.00 4.57  ? 146 ASN B ND2 1 
ATOM 5177 N N   . CYS B 1 163 ? 172.929 154.976 216.995 1.00 4.95  ? 147 CYS B N   1 
ATOM 5178 C CA  . CYS B 1 163 ? 174.049 155.797 216.555 1.00 4.95  ? 147 CYS B CA  1 
ATOM 5179 C C   . CYS B 1 163 ? 175.359 155.029 216.500 1.00 4.95  ? 147 CYS B C   1 
ATOM 5180 O O   . CYS B 1 163 ? 176.360 155.577 216.029 1.00 4.95  ? 147 CYS B O   1 
ATOM 5181 C CB  . CYS B 1 163 ? 174.221 157.014 217.470 1.00 4.95  ? 147 CYS B CB  1 
ATOM 5182 S SG  . CYS B 1 163 ? 173.369 158.506 216.917 1.00 4.95  ? 147 CYS B SG  1 
ATOM 5183 N N   . LEU B 1 164 ? 175.385 153.782 216.971 1.00 5.29  ? 148 LEU B N   1 
ATOM 5184 C CA  . LEU B 1 164 ? 176.605 152.991 216.952 1.00 5.29  ? 148 LEU B CA  1 
ATOM 5185 C C   . LEU B 1 164 ? 176.540 151.767 216.055 1.00 5.29  ? 148 LEU B C   1 
ATOM 5186 O O   . LEU B 1 164 ? 177.593 151.303 215.608 1.00 5.29  ? 148 LEU B O   1 
ATOM 5187 C CB  . LEU B 1 164 ? 176.985 152.541 218.370 1.00 5.29  ? 148 LEU B CB  1 
ATOM 5188 C CG  . LEU B 1 164 ? 178.115 153.382 218.962 1.00 5.29  ? 148 LEU B CG  1 
ATOM 5189 C CD1 . LEU B 1 164 ? 179.398 153.091 218.212 1.00 5.29  ? 148 LEU B CD1 1 
ATOM 5190 C CD2 . LEU B 1 164 ? 177.796 154.865 218.932 1.00 5.29  ? 148 LEU B CD2 1 
ATOM 5191 N N   . GLN B 1 165 ? 175.354 151.227 215.785 1.00 7.02  ? 149 GLN B N   1 
ATOM 5192 C CA  . GLN B 1 165 ? 175.233 150.180 214.782 1.00 7.02  ? 149 GLN B CA  1 
ATOM 5193 C C   . GLN B 1 165 ? 175.406 150.731 213.375 1.00 7.02  ? 149 GLN B C   1 
ATOM 5194 O O   . GLN B 1 165 ? 175.884 150.008 212.495 1.00 7.02  ? 149 GLN B O   1 
ATOM 5195 C CB  . GLN B 1 165 ? 173.880 149.472 214.919 1.00 7.02  ? 149 GLN B CB  1 
ATOM 5196 C CG  . GLN B 1 165 ? 173.770 148.141 214.177 1.00 7.02  ? 149 GLN B CG  1 
ATOM 5197 C CD  . GLN B 1 165 ? 173.484 148.302 212.698 1.00 7.02  ? 149 GLN B CD  1 
ATOM 5198 O OE1 . GLN B 1 165 ? 172.955 149.324 212.265 1.00 7.02  ? 149 GLN B OE1 1 
ATOM 5199 N NE2 . GLN B 1 165 ? 173.840 147.292 211.913 1.00 7.02  ? 149 GLN B NE2 1 
ATOM 5200 N N   . VAL B 1 166 ? 175.046 151.994 213.153 1.00 5.04  ? 150 VAL B N   1 
ATOM 5201 C CA  . VAL B 1 166 ? 175.331 152.673 211.902 1.00 5.04  ? 150 VAL B CA  1 
ATOM 5202 C C   . VAL B 1 166 ? 176.783 153.136 211.819 1.00 5.04  ? 150 VAL B C   1 
ATOM 5203 O O   . VAL B 1 166 ? 177.370 153.099 210.731 1.00 5.04  ? 150 VAL B O   1 
ATOM 5204 C CB  . VAL B 1 166 ? 174.365 153.861 211.707 1.00 5.04  ? 150 VAL B CB  1 
ATOM 5205 C CG1 . VAL B 1 166 ? 174.870 154.815 210.636 1.00 5.04  ? 150 VAL B CG1 1 
ATOM 5206 C CG2 . VAL B 1 166 ? 172.972 153.357 211.368 1.00 5.04  ? 150 VAL B CG2 1 
ATOM 5207 N N   . MET B 1 167 ? 177.385 153.541 212.940 1.00 6.05  ? 151 MET B N   1 
ATOM 5208 C CA  . MET B 1 167 ? 178.789 153.937 212.942 1.00 6.05  ? 151 MET B CA  1 
ATOM 5209 C C   . MET B 1 167 ? 179.685 152.813 212.443 1.00 6.05  ? 151 MET B C   1 
ATOM 5210 O O   . MET B 1 167 ? 180.545 153.032 211.583 1.00 6.05  ? 151 MET B O   1 
ATOM 5211 C CB  . MET B 1 167 ? 179.208 154.347 214.351 1.00 6.05  ? 151 MET B CB  1 
ATOM 5212 C CG  . MET B 1 167 ? 180.458 155.194 214.414 1.00 6.05  ? 151 MET B CG  1 
ATOM 5213 S SD  . MET B 1 167 ? 180.499 156.182 215.916 1.00 6.05  ? 151 MET B SD  1 
ATOM 5214 C CE  . MET B 1 167 ? 180.514 157.823 215.219 1.00 6.05  ? 151 MET B CE  1 
ATOM 5215 N N   . TRP B 1 168 ? 179.499 151.602 212.972 1.00 11.41 ? 152 TRP B N   1 
ATOM 5216 C CA  . TRP B 1 168 ? 180.342 150.485 212.563 1.00 11.41 ? 152 TRP B CA  1 
ATOM 5217 C C   . TRP B 1 168 ? 180.016 150.034 211.148 1.00 11.41 ? 152 TRP B C   1 
ATOM 5218 O O   . TRP B 1 168 ? 180.894 149.531 210.438 1.00 11.41 ? 152 TRP B O   1 
ATOM 5219 C CB  . TRP B 1 168 ? 180.190 149.328 213.549 1.00 11.41 ? 152 TRP B CB  1 
ATOM 5220 C CG  . TRP B 1 168 ? 181.413 148.476 213.662 1.00 11.41 ? 152 TRP B CG  1 
ATOM 5221 C CD1 . TRP B 1 168 ? 182.627 148.704 213.083 1.00 11.41 ? 152 TRP B CD1 1 
ATOM 5222 C CD2 . TRP B 1 168 ? 181.551 147.268 214.419 1.00 11.41 ? 152 TRP B CD2 1 
ATOM 5223 N NE1 . TRP B 1 168 ? 183.509 147.707 213.423 1.00 11.41 ? 152 TRP B NE1 1 
ATOM 5224 C CE2 . TRP B 1 168 ? 182.873 146.813 214.243 1.00 11.41 ? 152 TRP B CE2 1 
ATOM 5225 C CE3 . TRP B 1 168 ? 180.683 146.524 215.224 1.00 11.41 ? 152 TRP B CE3 1 
ATOM 5226 C CZ2 . TRP B 1 168 ? 183.348 145.649 214.843 1.00 11.41 ? 152 TRP B CZ2 1 
ATOM 5227 C CZ3 . TRP B 1 168 ? 181.156 145.368 215.819 1.00 11.41 ? 152 TRP B CZ3 1 
ATOM 5228 C CH2 . TRP B 1 168 ? 182.476 144.942 215.625 1.00 11.41 ? 152 TRP B CH2 1 
ATOM 5229 N N   . LEU B 1 169 ? 178.762 150.199 210.721 1.00 5.25  ? 153 LEU B N   1 
ATOM 5230 C CA  . LEU B 1 169 ? 178.411 149.913 209.334 1.00 5.25  ? 153 LEU B CA  1 
ATOM 5231 C C   . LEU B 1 169 ? 179.112 150.874 208.384 1.00 5.25  ? 153 LEU B C   1 
ATOM 5232 O O   . LEU B 1 169 ? 179.544 150.477 207.296 1.00 5.25  ? 153 LEU B O   1 
ATOM 5233 C CB  . LEU B 1 169 ? 176.896 149.984 209.149 1.00 5.25  ? 153 LEU B CB  1 
ATOM 5234 C CG  . LEU B 1 169 ? 176.369 149.540 207.786 1.00 5.25  ? 153 LEU B CG  1 
ATOM 5235 C CD1 . LEU B 1 169 ? 176.959 148.195 207.407 1.00 5.25  ? 153 LEU B CD1 1 
ATOM 5236 C CD2 . LEU B 1 169 ? 174.854 149.477 207.799 1.00 5.25  ? 153 LEU B CD2 1 
ATOM 5237 N N   . ALA B 1 170 ? 179.224 152.145 208.773 1.00 4.30  ? 154 ALA B N   1 
ATOM 5238 C CA  . ALA B 1 170 ? 179.931 153.110 207.940 1.00 4.30  ? 154 ALA B CA  1 
ATOM 5239 C C   . ALA B 1 170 ? 181.408 152.768 207.817 1.00 4.30  ? 154 ALA B C   1 
ATOM 5240 O O   . ALA B 1 170 ? 181.990 152.917 206.737 1.00 4.30  ? 154 ALA B O   1 
ATOM 5241 C CB  . ALA B 1 170 ? 179.760 154.520 208.503 1.00 4.30  ? 154 ALA B CB  1 
ATOM 5242 N N   . ASP B 1 171 ? 182.032 152.315 208.901 1.00 8.98  ? 155 ASP B N   1 
ATOM 5243 C CA  . ASP B 1 171 ? 183.446 151.941 208.865 1.00 8.98  ? 155 ASP B CA  1 
ATOM 5244 C C   . ASP B 1 171 ? 183.627 150.475 208.483 1.00 8.98  ? 155 ASP B C   1 
ATOM 5245 O O   . ASP B 1 171 ? 184.348 149.716 209.128 1.00 8.98  ? 155 ASP B O   1 
ATOM 5246 C CB  . ASP B 1 171 ? 184.095 152.241 210.210 1.00 8.98  ? 155 ASP B CB  1 
ATOM 5247 C CG  . ASP B 1 171 ? 185.604 152.293 210.127 1.00 8.98  ? 155 ASP B CG  1 
ATOM 5248 O OD1 . ASP B 1 171 ? 186.130 153.153 209.391 1.00 8.98  ? 155 ASP B OD1 1 
ATOM 5249 O OD2 . ASP B 1 171 ? 186.264 151.471 210.796 1.00 8.98  ? 155 ASP B OD2 1 
ATOM 5250 N N   . ARG B 1 172 ? 182.950 150.075 207.410 1.00 7.82  ? 156 ARG B N   1 
ATOM 5251 C CA  . ARG B 1 172 ? 183.192 148.802 206.747 1.00 7.82  ? 156 ARG B CA  1 
ATOM 5252 C C   . ARG B 1 172 ? 183.203 148.911 205.233 1.00 7.82  ? 156 ARG B C   1 
ATOM 5253 O O   . ARG B 1 172 ? 183.781 148.037 204.576 1.00 7.82  ? 156 ARG B O   1 
ATOM 5254 C CB  . ARG B 1 172 ? 182.142 147.761 207.164 1.00 7.82  ? 156 ARG B CB  1 
ATOM 5255 C CG  . ARG B 1 172 ? 182.340 147.213 208.567 1.00 7.82  ? 156 ARG B CG  1 
ATOM 5256 C CD  . ARG B 1 172 ? 182.465 145.699 208.561 1.00 7.82  ? 156 ARG B CD  1 
ATOM 5257 N NE  . ARG B 1 172 ? 181.418 145.065 207.769 1.00 7.82  ? 156 ARG B NE  1 
ATOM 5258 C CZ  . ARG B 1 172 ? 180.211 144.764 208.228 1.00 7.82  ? 156 ARG B CZ  1 
ATOM 5259 N NH1 . ARG B 1 172 ? 179.861 145.025 209.477 1.00 7.82  ? 156 ARG B NH1 1 
ATOM 5260 N NH2 . ARG B 1 172 ? 179.333 144.186 207.413 1.00 7.82  ? 156 ARG B NH2 1 
ATOM 5261 N N   . HIS B 1 173 ? 182.591 149.948 204.661 1.00 6.40  ? 157 HIS B N   1 
ATOM 5262 C CA  . HIS B 1 173 ? 182.589 150.184 203.224 1.00 6.40  ? 157 HIS B CA  1 
ATOM 5263 C C   . HIS B 1 173 ? 183.253 151.507 202.864 1.00 6.40  ? 157 HIS B C   1 
ATOM 5264 O O   . HIS B 1 173 ? 183.217 151.908 201.694 1.00 6.40  ? 157 HIS B O   1 
ATOM 5265 C CB  . HIS B 1 173 ? 181.157 150.143 202.685 1.00 6.40  ? 157 HIS B CB  1 
ATOM 5266 C CG  . HIS B 1 173 ? 180.337 149.023 203.245 1.00 6.40  ? 157 HIS B CG  1 
ATOM 5267 N ND1 . HIS B 1 173 ? 180.148 147.833 202.578 1.00 6.40  ? 157 HIS B ND1 1 
ATOM 5268 C CD2 . HIS B 1 173 ? 179.664 148.909 204.414 1.00 6.40  ? 157 HIS B CD2 1 
ATOM 5269 C CE1 . HIS B 1 173 ? 179.390 147.035 203.309 1.00 6.40  ? 157 HIS B CE1 1 
ATOM 5270 N NE2 . HIS B 1 173 ? 179.083 147.665 204.428 1.00 6.40  ? 157 HIS B NE2 1 
ATOM 5271 N N   . SER B 1 174 ? 183.849 152.193 203.841 1.00 5.16  ? 158 SER B N   1 
ATOM 5272 C CA  . SER B 1 174 ? 184.586 153.438 203.628 1.00 5.16  ? 158 SER B CA  1 
ATOM 5273 C C   . SER B 1 174 ? 183.698 154.509 202.989 1.00 5.16  ? 158 SER B C   1 
ATOM 5274 O O   . SER B 1 174 ? 183.942 154.982 201.878 1.00 5.16  ? 158 SER B O   1 
ATOM 5275 C CB  . SER B 1 174 ? 185.847 153.189 202.793 1.00 5.16  ? 158 SER B CB  1 
ATOM 5276 O OG  . SER B 1 174 ? 186.707 152.263 203.434 1.00 5.16  ? 158 SER B OG  1 
ATOM 5277 N N   . ASP B 1 175 ? 182.652 154.884 203.720 1.00 4.26  ? 159 ASP B N   1 
ATOM 5278 C CA  . ASP B 1 175 ? 181.737 155.930 203.278 1.00 4.26  ? 159 ASP B CA  1 
ATOM 5279 C C   . ASP B 1 175 ? 181.865 157.137 204.195 1.00 4.26  ? 159 ASP B C   1 
ATOM 5280 O O   . ASP B 1 175 ? 181.381 157.092 205.337 1.00 4.26  ? 159 ASP B O   1 
ATOM 5281 C CB  . ASP B 1 175 ? 180.297 155.418 203.264 1.00 4.26  ? 159 ASP B CB  1 
ATOM 5282 C CG  . ASP B 1 175 ? 179.399 156.228 202.352 1.00 4.26  ? 159 ASP B CG  1 
ATOM 5283 O OD1 . ASP B 1 175 ? 179.834 156.561 201.229 1.00 4.26  ? 159 ASP B OD1 1 
ATOM 5284 O OD2 . ASP B 1 175 ? 178.255 156.527 202.753 1.00 4.26  ? 159 ASP B OD2 1 
ATOM 5285 N N   . PRO B 1 176 ? 182.502 158.228 203.758 1.00 4.54  ? 160 PRO B N   1 
ATOM 5286 C CA  . PRO B 1 176 ? 182.661 159.395 204.636 1.00 4.54  ? 160 PRO B CA  1 
ATOM 5287 C C   . PRO B 1 176 ? 181.406 160.236 204.798 1.00 4.54  ? 160 PRO B C   1 
ATOM 5288 O O   . PRO B 1 176 ? 181.320 160.999 205.769 1.00 4.54  ? 160 PRO B O   1 
ATOM 5289 C CB  . PRO B 1 176 ? 183.767 160.194 203.938 1.00 4.54  ? 160 PRO B CB  1 
ATOM 5290 C CG  . PRO B 1 176 ? 183.569 159.878 202.495 1.00 4.54  ? 160 PRO B CG  1 
ATOM 5291 C CD  . PRO B 1 176 ? 183.172 158.422 202.460 1.00 4.54  ? 160 PRO B CD  1 
ATOM 5292 N N   . GLU B 1 177 ? 180.435 160.128 203.890 1.00 5.61  ? 161 GLU B N   1 
ATOM 5293 C CA  . GLU B 1 177 ? 179.209 160.909 203.997 1.00 5.61  ? 161 GLU B CA  1 
ATOM 5294 C C   . GLU B 1 177 ? 178.294 160.429 205.116 1.00 5.61  ? 161 GLU B C   1 
ATOM 5295 O O   . GLU B 1 177 ? 177.352 161.145 205.472 1.00 5.61  ? 161 GLU B O   1 
ATOM 5296 C CB  . GLU B 1 177 ? 178.449 160.882 202.669 1.00 5.61  ? 161 GLU B CB  1 
ATOM 5297 C CG  . GLU B 1 177 ? 179.101 161.699 201.566 1.00 5.61  ? 161 GLU B CG  1 
ATOM 5298 C CD  . GLU B 1 177 ? 178.526 161.394 200.197 1.00 5.61  ? 161 GLU B CD  1 
ATOM 5299 O OE1 . GLU B 1 177 ? 177.553 160.615 200.120 1.00 5.61  ? 161 GLU B OE1 1 
ATOM 5300 O OE2 . GLU B 1 177 ? 179.045 161.936 199.198 1.00 5.61  ? 161 GLU B OE2 1 
ATOM 5301 N N   . LEU B 1 178 ? 178.543 159.246 205.670 1.00 3.86  ? 162 LEU B N   1 
ATOM 5302 C CA  . LEU B 1 178 ? 177.784 158.715 206.795 1.00 3.86  ? 162 LEU B CA  1 
ATOM 5303 C C   . LEU B 1 178 ? 178.598 158.630 208.074 1.00 3.86  ? 162 LEU B C   1 
ATOM 5304 O O   . LEU B 1 178 ? 178.069 158.896 209.155 1.00 3.86  ? 162 LEU B O   1 
ATOM 5305 C CB  . LEU B 1 178 ? 177.237 157.324 206.452 1.00 3.86  ? 162 LEU B CB  1 
ATOM 5306 C CG  . LEU B 1 178 ? 176.518 156.576 207.574 1.00 3.86  ? 162 LEU B CG  1 
ATOM 5307 C CD1 . LEU B 1 178 ? 175.237 157.291 207.946 1.00 3.86  ? 162 LEU B CD1 1 
ATOM 5308 C CD2 . LEU B 1 178 ? 176.234 155.145 207.165 1.00 3.86  ? 162 LEU B CD2 1 
ATOM 5309 N N   . TYR B 1 179 ? 179.881 158.275 207.974 1.00 5.50  ? 163 TYR B N   1 
ATOM 5310 C CA  . TYR B 1 179 ? 180.728 158.217 209.160 1.00 5.50  ? 163 TYR B CA  1 
ATOM 5311 C C   . TYR B 1 179 ? 180.926 159.596 209.773 1.00 5.50  ? 163 TYR B C   1 
ATOM 5312 O O   . TYR B 1 179 ? 181.065 159.716 210.995 1.00 5.50  ? 163 TYR B O   1 
ATOM 5313 C CB  . TYR B 1 179 ? 182.075 157.591 208.807 1.00 5.50  ? 163 TYR B CB  1 
ATOM 5314 C CG  . TYR B 1 179 ? 182.996 157.398 209.988 1.00 5.50  ? 163 TYR B CG  1 
ATOM 5315 C CD1 . TYR B 1 179 ? 182.747 156.413 210.931 1.00 5.50  ? 163 TYR B CD1 1 
ATOM 5316 C CD2 . TYR B 1 179 ? 184.119 158.195 210.153 1.00 5.50  ? 163 TYR B CD2 1 
ATOM 5317 C CE1 . TYR B 1 179 ? 183.588 156.230 212.010 1.00 5.50  ? 163 TYR B CE1 1 
ATOM 5318 C CE2 . TYR B 1 179 ? 184.966 158.020 211.228 1.00 5.50  ? 163 TYR B CE2 1 
ATOM 5319 C CZ  . TYR B 1 179 ? 184.695 157.036 212.153 1.00 5.50  ? 163 TYR B CZ  1 
ATOM 5320 O OH  . TYR B 1 179 ? 185.536 156.858 213.227 1.00 5.50  ? 163 TYR B OH  1 
ATOM 5321 N N   . THR B 1 180 ? 180.945 160.643 208.951 1.00 6.17  ? 164 THR B N   1 
ATOM 5322 C CA  . THR B 1 180 ? 181.020 162.012 209.442 1.00 6.17  ? 164 THR B CA  1 
ATOM 5323 C C   . THR B 1 180 ? 179.649 162.602 209.742 1.00 6.17  ? 164 THR B C   1 
ATOM 5324 O O   . THR B 1 180 ? 179.570 163.726 210.248 1.00 6.17  ? 164 THR B O   1 
ATOM 5325 C CB  . THR B 1 180 ? 181.749 162.905 208.432 1.00 6.17  ? 164 THR B CB  1 
ATOM 5326 O OG1 . THR B 1 180 ? 181.038 162.905 207.189 1.00 6.17  ? 164 THR B OG1 1 
ATOM 5327 C CG2 . THR B 1 180 ? 183.166 162.402 208.202 1.00 6.17  ? 164 THR B CG2 1 
ATOM 5328 N N   . ALA B 1 181 ? 178.572 161.875 209.441 1.00 5.83  ? 165 ALA B N   1 
ATOM 5329 C CA  . ALA B 1 181 ? 177.225 162.287 209.801 1.00 5.83  ? 165 ALA B CA  1 
ATOM 5330 C C   . ALA B 1 181 ? 176.623 161.467 210.928 1.00 5.83  ? 165 ALA B C   1 
ATOM 5331 O O   . ALA B 1 181 ? 175.666 161.929 211.559 1.00 5.83  ? 165 ALA B O   1 
ATOM 5332 C CB  . ALA B 1 181 ? 176.292 162.214 208.582 1.00 5.83  ? 165 ALA B CB  1 
ATOM 5333 N N   . ALA B 1 182 ? 177.144 160.273 211.195 1.00 5.50  ? 166 ALA B N   1 
ATOM 5334 C CA  . ALA B 1 182 ? 176.779 159.504 212.374 1.00 5.50  ? 166 ALA B CA  1 
ATOM 5335 C C   . ALA B 1 182 ? 177.682 159.807 213.558 1.00 5.50  ? 166 ALA B C   1 
ATOM 5336 O O   . ALA B 1 182 ? 177.552 159.160 214.601 1.00 5.50  ? 166 ALA B O   1 
ATOM 5337 C CB  . ALA B 1 182 ? 176.815 158.005 212.067 1.00 5.50  ? 166 ALA B CB  1 
ATOM 5338 N N   . LYS B 1 183 ? 178.601 160.760 213.412 1.00 9.40  ? 167 LYS B N   1 
ATOM 5339 C CA  . LYS B 1 183 ? 179.459 161.216 214.497 1.00 9.40  ? 167 LYS B CA  1 
ATOM 5340 C C   . LYS B 1 183 ? 178.977 162.511 215.131 1.00 9.40  ? 167 LYS B C   1 
ATOM 5341 O O   . LYS B 1 183 ? 179.127 162.686 216.344 1.00 9.40  ? 167 LYS B O   1 
ATOM 5342 C CB  . LYS B 1 183 ? 180.893 161.403 213.988 1.00 9.40  ? 167 LYS B CB  1 
ATOM 5343 C CG  . LYS B 1 183 ? 181.970 160.974 214.968 1.00 9.40  ? 167 LYS B CG  1 
ATOM 5344 C CD  . LYS B 1 183 ? 183.361 161.115 214.370 1.00 9.40  ? 167 LYS B CD  1 
ATOM 5345 C CE  . LYS B 1 183 ? 183.485 162.363 213.514 1.00 9.40  ? 167 LYS B CE  1 
ATOM 5346 N NZ  . LYS B 1 183 ? 184.818 162.452 212.858 1.00 9.40  ? 167 LYS B NZ  1 
ATOM 5347 N N   . HIS B 1 184 ? 178.398 163.419 214.341 1.00 11.18 ? 168 HIS B N   1 
ATOM 5348 C CA  . HIS B 1 184 ? 177.837 164.641 214.905 1.00 11.18 ? 168 HIS B CA  1 
ATOM 5349 C C   . HIS B 1 184 ? 176.601 164.354 215.745 1.00 11.18 ? 168 HIS B C   1 
ATOM 5350 O O   . HIS B 1 184 ? 176.270 165.135 216.644 1.00 11.18 ? 168 HIS B O   1 
ATOM 5351 C CB  . HIS B 1 184 ? 177.498 165.628 213.789 1.00 11.18 ? 168 HIS B CB  1 
ATOM 5352 C CG  . HIS B 1 184 ? 178.695 166.294 213.185 1.00 11.18 ? 168 HIS B CG  1 
ATOM 5353 N ND1 . HIS B 1 184 ? 178.797 167.662 213.050 1.00 11.18 ? 168 HIS B ND1 1 
ATOM 5354 C CD2 . HIS B 1 184 ? 179.842 165.780 212.680 1.00 11.18 ? 168 HIS B CD2 1 
ATOM 5355 C CE1 . HIS B 1 184 ? 179.954 167.962 212.487 1.00 11.18 ? 168 HIS B CE1 1 
ATOM 5356 N NE2 . HIS B 1 184 ? 180.607 166.838 212.253 1.00 11.18 ? 168 HIS B NE2 1 
ATOM 5357 N N   . CYS B 1 185 ? 175.904 163.255 215.466 1.00 10.03 ? 169 CYS B N   1 
ATOM 5358 C CA  . CYS B 1 185 ? 174.719 162.871 216.219 1.00 10.03 ? 169 CYS B CA  1 
ATOM 5359 C C   . CYS B 1 185 ? 175.007 161.813 217.276 1.00 10.03 ? 169 CYS B C   1 
ATOM 5360 O O   . CYS B 1 185 ? 174.083 161.396 217.982 1.00 10.03 ? 169 CYS B O   1 
ATOM 5361 C CB  . CYS B 1 185 ? 173.631 162.368 215.264 1.00 10.03 ? 169 CYS B CB  1 
ATOM 5362 S SG  . CYS B 1 185 ? 171.953 162.396 215.940 1.00 10.03 ? 169 CYS B SG  1 
ATOM 5363 N N   . ALA B 1 186 ? 176.258 161.372 217.408 1.00 8.62  ? 170 ALA B N   1 
ATOM 5364 C CA  . ALA B 1 186 ? 176.629 160.388 218.413 1.00 8.62  ? 170 ALA B CA  1 
ATOM 5365 C C   . ALA B 1 186 ? 177.616 160.915 219.443 1.00 8.62  ? 170 ALA B C   1 
ATOM 5366 O O   . ALA B 1 186 ? 177.852 160.237 220.449 1.00 8.62  ? 170 ALA B O   1 
ATOM 5367 C CB  . ALA B 1 186 ? 177.220 159.137 217.749 1.00 8.62  ? 170 ALA B CB  1 
ATOM 5368 N N   . LYS B 1 187 ? 178.204 162.090 219.222 1.00 11.82 ? 171 LYS B N   1 
ATOM 5369 C CA  . LYS B 1 187 ? 179.086 162.696 220.210 1.00 11.82 ? 171 LYS B CA  1 
ATOM 5370 C C   . LYS B 1 187 ? 178.378 163.711 221.093 1.00 11.82 ? 171 LYS B C   1 
ATOM 5371 O O   . LYS B 1 187 ? 178.797 163.918 222.236 1.00 11.82 ? 171 LYS B O   1 
ATOM 5372 C CB  . LYS B 1 187 ? 180.282 163.368 219.525 1.00 11.82 ? 171 LYS B CB  1 
ATOM 5373 C CG  . LYS B 1 187 ? 179.948 164.647 218.775 1.00 11.82 ? 171 LYS B CG  1 
ATOM 5374 C CD  . LYS B 1 187 ? 181.203 165.313 218.240 1.00 11.82 ? 171 LYS B CD  1 
ATOM 5375 C CE  . LYS B 1 187 ? 180.942 166.761 217.857 1.00 11.82 ? 171 LYS B CE  1 
ATOM 5376 N NZ  . LYS B 1 187 ? 179.923 166.881 216.778 1.00 11.82 ? 171 LYS B NZ  1 
ATOM 5377 N N   . THR B 1 188 ? 177.318 164.351 220.592 1.00 12.09 ? 172 THR B N   1 
ATOM 5378 C CA  . THR B 1 188 ? 176.546 165.263 221.428 1.00 12.09 ? 172 THR B CA  1 
ATOM 5379 C C   . THR B 1 188 ? 175.845 164.515 222.555 1.00 12.09 ? 172 THR B C   1 
ATOM 5380 O O   . THR B 1 188 ? 175.833 164.978 223.701 1.00 12.09 ? 172 THR B O   1 
ATOM 5381 C CB  . THR B 1 188 ? 175.531 166.030 220.581 1.00 12.09 ? 172 THR B CB  1 
ATOM 5382 O OG1 . THR B 1 188 ? 174.609 165.110 219.984 1.00 12.09 ? 172 THR B OG1 1 
ATOM 5383 C CG2 . THR B 1 188 ? 176.236 166.816 219.487 1.00 12.09 ? 172 THR B CG2 1 
ATOM 5384 N N   . HIS B 1 189 ? 175.259 163.363 222.253 1.00 11.84 ? 173 HIS B N   1 
ATOM 5385 C CA  . HIS B 1 189 ? 174.602 162.531 223.263 1.00 11.84 ? 173 HIS B CA  1 
ATOM 5386 C C   . HIS B 1 189 ? 175.565 161.502 223.840 1.00 11.84 ? 173 HIS B C   1 
ATOM 5387 O O   . HIS B 1 189 ? 175.269 160.309 223.892 1.00 11.84 ? 173 HIS B O   1 
ATOM 5388 C CB  . HIS B 1 189 ? 173.375 161.850 222.670 1.00 11.84 ? 173 HIS B CB  1 
ATOM 5389 C CG  . HIS B 1 189 ? 172.495 162.766 221.879 1.00 11.84 ? 173 HIS B CG  1 
ATOM 5390 N ND1 . HIS B 1 189 ? 171.553 163.583 222.465 1.00 11.84 ? 173 HIS B ND1 1 
ATOM 5391 C CD2 . HIS B 1 189 ? 172.404 162.984 220.546 1.00 11.84 ? 173 HIS B CD2 1 
ATOM 5392 C CE1 . HIS B 1 189 ? 170.925 164.270 221.528 1.00 11.84 ? 173 HIS B CE1 1 
ATOM 5393 N NE2 . HIS B 1 189 ? 171.422 163.925 220.355 1.00 11.84 ? 173 HIS B NE2 1 
ATOM 5394 N N   . LEU B 1 190 ? 176.737 161.957 224.287 1.00 13.63 ? 174 LEU B N   1 
ATOM 5395 C CA  . LEU B 1 190 ? 177.708 161.033 224.860 1.00 13.63 ? 174 LEU B CA  1 
ATOM 5396 C C   . LEU B 1 190 ? 177.301 160.586 226.257 1.00 13.63 ? 174 LEU B C   1 
ATOM 5397 O O   . LEU B 1 190 ? 177.596 159.453 226.654 1.00 13.63 ? 174 LEU B O   1 
ATOM 5398 C CB  . LEU B 1 190 ? 179.094 161.678 224.887 1.00 13.63 ? 174 LEU B CB  1 
ATOM 5399 C CG  . LEU B 1 190 ? 180.262 160.780 225.302 1.00 13.63 ? 174 LEU B CG  1 
ATOM 5400 C CD1 . LEU B 1 190 ? 180.346 159.561 224.400 1.00 13.63 ? 174 LEU B CD1 1 
ATOM 5401 C CD2 . LEU B 1 190 ? 181.568 161.554 225.279 1.00 13.63 ? 174 LEU B CD2 1 
ATOM 5402 N N   . ALA B 1 191 ? 176.624 161.455 227.012 1.00 15.97 ? 175 ALA B N   1 
ATOM 5403 C CA  . ALA B 1 191 ? 176.243 161.112 228.378 1.00 15.97 ? 175 ALA B CA  1 
ATOM 5404 C C   . ALA B 1 191 ? 175.267 159.943 228.411 1.00 15.97 ? 175 ALA B C   1 
ATOM 5405 O O   . ALA B 1 191 ? 175.409 159.030 229.232 1.00 15.97 ? 175 ALA B O   1 
ATOM 5406 C CB  . ALA B 1 191 ? 175.642 162.331 229.077 1.00 15.97 ? 175 ALA B CB  1 
ATOM 5407 N N   . GLN B 1 192 ? 174.265 159.952 227.528 1.00 17.90 ? 176 GLN B N   1 
ATOM 5408 C CA  . GLN B 1 192 ? 173.282 158.874 227.531 1.00 17.90 ? 176 GLN B CA  1 
ATOM 5409 C C   . GLN B 1 192 ? 173.886 157.575 227.013 1.00 17.90 ? 176 GLN B C   1 
ATOM 5410 O O   . GLN B 1 192 ? 173.534 156.488 227.487 1.00 17.90 ? 176 GLN B O   1 
ATOM 5411 C CB  . GLN B 1 192 ? 172.060 159.266 226.700 1.00 17.90 ? 176 GLN B CB  1 
ATOM 5412 C CG  . GLN B 1 192 ? 170.775 158.584 227.147 1.00 17.90 ? 176 GLN B CG  1 
ATOM 5413 C CD  . GLN B 1 192 ? 170.620 157.189 226.577 1.00 17.90 ? 176 GLN B CD  1 
ATOM 5414 O OE1 . GLN B 1 192 ? 170.542 157.005 225.364 1.00 17.90 ? 176 GLN B OE1 1 
ATOM 5415 N NE2 . GLN B 1 192 ? 170.575 156.194 227.455 1.00 17.90 ? 176 GLN B NE2 1 
ATOM 5416 N N   . LEU B 1 193 ? 174.794 157.665 226.038 1.00 15.08 ? 177 LEU B N   1 
ATOM 5417 C CA  . LEU B 1 193 ? 175.439 156.471 225.506 1.00 15.08 ? 177 LEU B CA  1 
ATOM 5418 C C   . LEU B 1 193 ? 176.352 155.801 226.524 1.00 15.08 ? 177 LEU B C   1 
ATOM 5419 O O   . LEU B 1 193 ? 176.729 154.642 226.328 1.00 15.08 ? 177 LEU B O   1 
ATOM 5420 C CB  . LEU B 1 193 ? 176.237 156.816 224.247 1.00 15.08 ? 177 LEU B CB  1 
ATOM 5421 C CG  . LEU B 1 193 ? 175.453 156.997 222.947 1.00 15.08 ? 177 LEU B CG  1 
ATOM 5422 C CD1 . LEU B 1 193 ? 176.364 157.510 221.845 1.00 15.08 ? 177 LEU B CD1 1 
ATOM 5423 C CD2 . LEU B 1 193 ? 174.796 155.692 222.532 1.00 15.08 ? 177 LEU B CD2 1 
ATOM 5424 N N   . GLN B 1 194 ? 176.709 156.502 227.603 1.00 17.19 ? 178 GLN B N   1 
ATOM 5425 C CA  . GLN B 1 194 ? 177.614 155.936 228.598 1.00 17.19 ? 178 GLN B CA  1 
ATOM 5426 C C   . GLN B 1 194 ? 177.022 154.690 229.246 1.00 17.19 ? 178 GLN B C   1 
ATOM 5427 O O   . GLN B 1 194 ? 177.725 153.695 229.453 1.00 17.19 ? 178 GLN B O   1 
ATOM 5428 C CB  . GLN B 1 194 ? 177.940 156.987 229.657 1.00 17.19 ? 178 GLN B CB  1 
ATOM 5429 C CG  . GLN B 1 194 ? 178.890 156.513 230.737 1.00 17.19 ? 178 GLN B CG  1 
ATOM 5430 C CD  . GLN B 1 194 ? 179.776 157.627 231.250 1.00 17.19 ? 178 GLN B CD  1 
ATOM 5431 O OE1 . GLN B 1 194 ? 180.998 157.499 231.275 1.00 17.19 ? 178 GLN B OE1 1 
ATOM 5432 N NE2 . GLN B 1 194 ? 179.163 158.731 231.662 1.00 17.19 ? 178 GLN B NE2 1 
ATOM 5433 N N   . ASN B 1 195 ? 175.730 154.727 229.575 1.00 14.47 ? 179 ASN B N   1 
ATOM 5434 C CA  . ASN B 1 195 ? 175.076 153.594 230.215 1.00 14.47 ? 179 ASN B CA  1 
ATOM 5435 C C   . ASN B 1 195 ? 174.848 152.428 229.259 1.00 14.47 ? 179 ASN B C   1 
ATOM 5436 O O   . ASN B 1 195 ? 174.702 151.291 229.720 1.00 14.47 ? 179 ASN B O   1 
ATOM 5437 C CB  . ASN B 1 195 ? 173.744 154.048 230.821 1.00 14.47 ? 179 ASN B CB  1 
ATOM 5438 C CG  . ASN B 1 195 ? 173.028 152.940 231.569 1.00 14.47 ? 179 ASN B CG  1 
ATOM 5439 O OD1 . ASN B 1 195 ? 173.658 152.051 232.140 1.00 14.47 ? 179 ASN B OD1 1 
ATOM 5440 N ND2 . ASN B 1 195 ? 171.701 152.990 231.568 1.00 14.47 ? 179 ASN B ND2 1 
ATOM 5441 N N   . THR B 1 196 ? 174.830 152.677 227.952 1.00 14.99 ? 180 THR B N   1 
ATOM 5442 C CA  . THR B 1 196 ? 174.564 151.624 226.984 1.00 14.99 ? 180 THR B CA  1 
ATOM 5443 C C   . THR B 1 196 ? 175.679 150.580 226.990 1.00 14.99 ? 180 THR B C   1 
ATOM 5444 O O   . THR B 1 196 ? 176.853 150.880 227.227 1.00 14.99 ? 180 THR B O   1 
ATOM 5445 C CB  . THR B 1 196 ? 174.412 152.210 225.580 1.00 14.99 ? 180 THR B CB  1 
ATOM 5446 O OG1 . THR B 1 196 ? 175.629 152.861 225.198 1.00 14.99 ? 180 THR B OG1 1 
ATOM 5447 C CG2 . THR B 1 196 ? 173.274 153.218 225.546 1.00 14.99 ? 180 THR B CG2 1 
ATOM 5448 N N   . GLU B 1 197 ? 175.291 149.331 226.723 1.00 17.61 ? 181 GLU B N   1 
ATOM 5449 C CA  . GLU B 1 197 ? 176.249 148.232 226.712 1.00 17.61 ? 181 GLU B CA  1 
ATOM 5450 C C   . GLU B 1 197 ? 177.126 148.245 225.466 1.00 17.61 ? 181 GLU B C   1 
ATOM 5451 O O   . GLU B 1 197 ? 178.268 147.773 225.515 1.00 17.61 ? 181 GLU B O   1 
ATOM 5452 C CB  . GLU B 1 197 ? 175.527 146.882 226.822 1.00 17.61 ? 181 GLU B CB  1 
ATOM 5453 C CG  . GLU B 1 197 ? 174.550 146.536 225.687 1.00 17.61 ? 181 GLU B CG  1 
ATOM 5454 C CD  . GLU B 1 197 ? 173.361 147.478 225.579 1.00 17.61 ? 181 GLU B CD  1 
ATOM 5455 O OE1 . GLU B 1 197 ? 173.087 148.216 226.549 1.00 17.61 ? 181 GLU B OE1 1 
ATOM 5456 O OE2 . GLU B 1 197 ? 172.700 147.480 224.519 1.00 17.61 ? 181 GLU B OE2 1 
ATOM 5457 N N   . GLU B 1 198 ? 176.616 148.769 224.349 1.00 17.46 ? 182 GLU B N   1 
ATOM 5458 C CA  . GLU B 1 198 ? 177.401 148.807 223.120 1.00 17.46 ? 182 GLU B CA  1 
ATOM 5459 C C   . GLU B 1 198 ? 178.596 149.742 223.244 1.00 17.46 ? 182 GLU B C   1 
ATOM 5460 O O   . GLU B 1 198 ? 179.645 149.491 222.639 1.00 17.46 ? 182 GLU B O   1 
ATOM 5461 C CB  . GLU B 1 198 ? 176.513 149.227 221.947 1.00 17.46 ? 182 GLU B CB  1 
ATOM 5462 C CG  . GLU B 1 198 ? 177.231 149.317 220.611 1.00 17.46 ? 182 GLU B CG  1 
ATOM 5463 C CD  . GLU B 1 198 ? 177.622 147.957 220.068 1.00 17.46 ? 182 GLU B CD  1 
ATOM 5464 O OE1 . GLU B 1 198 ? 176.934 146.967 220.391 1.00 17.46 ? 182 GLU B OE1 1 
ATOM 5465 O OE2 . GLU B 1 198 ? 178.617 147.878 219.316 1.00 17.46 ? 182 GLU B OE2 1 
ATOM 5466 N N   . PHE B 1 199 ? 178.459 150.817 224.022 1.00 17.00 ? 183 PHE B N   1 
ATOM 5467 C CA  . PHE B 1 199 ? 179.549 151.777 224.169 1.00 17.00 ? 183 PHE B CA  1 
ATOM 5468 C C   . PHE B 1 199 ? 180.758 151.148 224.853 1.00 17.00 ? 183 PHE B C   1 
ATOM 5469 O O   . PHE B 1 199 ? 181.903 151.432 224.483 1.00 17.00 ? 183 PHE B O   1 
ATOM 5470 C CB  . PHE B 1 199 ? 179.061 152.997 224.949 1.00 17.00 ? 183 PHE B CB  1 
ATOM 5471 C CG  . PHE B 1 199 ? 180.118 154.036 225.182 1.00 17.00 ? 183 PHE B CG  1 
ATOM 5472 C CD1 . PHE B 1 199 ? 180.509 154.884 224.161 1.00 17.00 ? 183 PHE B CD1 1 
ATOM 5473 C CD2 . PHE B 1 199 ? 180.711 154.175 226.425 1.00 17.00 ? 183 PHE B CD2 1 
ATOM 5474 C CE1 . PHE B 1 199 ? 181.475 155.845 224.372 1.00 17.00 ? 183 PHE B CE1 1 
ATOM 5475 C CE2 . PHE B 1 199 ? 181.679 155.134 226.641 1.00 17.00 ? 183 PHE B CE2 1 
ATOM 5476 C CZ  . PHE B 1 199 ? 182.062 155.970 225.613 1.00 17.00 ? 183 PHE B CZ  1 
ATOM 5477 N N   . LEU B 1 200 ? 180.526 150.294 225.852 1.00 20.55 ? 184 LEU B N   1 
ATOM 5478 C CA  . LEU B 1 200 ? 181.632 149.686 226.583 1.00 20.55 ? 184 LEU B CA  1 
ATOM 5479 C C   . LEU B 1 200 ? 182.422 148.694 225.737 1.00 20.55 ? 184 LEU B C   1 
ATOM 5480 O O   . LEU B 1 200 ? 183.577 148.404 226.067 1.00 20.55 ? 184 LEU B O   1 
ATOM 5481 C CB  . LEU B 1 200 ? 181.111 148.996 227.845 1.00 20.55 ? 184 LEU B CB  1 
ATOM 5482 C CG  . LEU B 1 200 ? 180.405 149.890 228.867 1.00 20.55 ? 184 LEU B CG  1 
ATOM 5483 C CD1 . LEU B 1 200 ? 179.779 149.055 229.972 1.00 20.55 ? 184 LEU B CD1 1 
ATOM 5484 C CD2 . LEU B 1 200 ? 181.371 150.911 229.448 1.00 20.55 ? 184 LEU B CD2 1 
ATOM 5485 N N   . HIS B 1 201 ? 181.837 148.176 224.656 1.00 19.68 ? 185 HIS B N   1 
ATOM 5486 C CA  . HIS B 1 201 ? 182.509 147.236 223.768 1.00 19.68 ? 185 HIS B CA  1 
ATOM 5487 C C   . HIS B 1 201 ? 183.130 147.924 222.559 1.00 19.68 ? 185 HIS B C   1 
ATOM 5488 O O   . HIS B 1 201 ? 183.422 147.263 221.556 1.00 19.68 ? 185 HIS B O   1 
ATOM 5489 C CB  . HIS B 1 201 ? 181.536 146.148 223.309 1.00 19.68 ? 185 HIS B CB  1 
ATOM 5490 C CG  . HIS B 1 201 ? 181.157 145.178 224.384 1.00 19.68 ? 185 HIS B CG  1 
ATOM 5491 N ND1 . HIS B 1 201 ? 180.266 144.148 224.175 1.00 19.68 ? 185 HIS B ND1 1 
ATOM 5492 C CD2 . HIS B 1 201 ? 181.557 145.073 225.674 1.00 19.68 ? 185 HIS B CD2 1 
ATOM 5493 C CE1 . HIS B 1 201 ? 180.128 143.454 225.290 1.00 19.68 ? 185 HIS B CE1 1 
ATOM 5494 N NE2 . HIS B 1 201 ? 180.900 143.995 226.215 1.00 19.68 ? 185 HIS B NE2 1 
ATOM 5495 N N   . LEU B 1 202 ? 183.329 149.235 222.632 1.00 16.60 ? 186 LEU B N   1 
ATOM 5496 C CA  . LEU B 1 202 ? 183.799 149.982 221.478 1.00 16.60 ? 186 LEU B CA  1 
ATOM 5497 C C   . LEU B 1 202 ? 185.241 149.610 221.143 1.00 16.60 ? 186 LEU B C   1 
ATOM 5498 O O   . LEU B 1 202 ? 186.072 149.458 222.045 1.00 16.60 ? 186 LEU B O   1 
ATOM 5499 C CB  . LEU B 1 202 ? 183.704 151.482 221.738 1.00 16.60 ? 186 LEU B CB  1 
ATOM 5500 C CG  . LEU B 1 202 ? 183.075 152.233 220.571 1.00 16.60 ? 186 LEU B CG  1 
ATOM 5501 C CD1 . LEU B 1 202 ? 181.652 151.750 220.438 1.00 16.60 ? 186 LEU B CD1 1 
ATOM 5502 C CD2 . LEU B 1 202 ? 183.123 153.735 220.771 1.00 16.60 ? 186 LEU B CD2 1 
ATOM 5503 N N   . PRO B 1 203 ? 185.566 149.454 219.863 1.00 17.52 ? 187 PRO B N   1 
ATOM 5504 C CA  . PRO B 1 203 ? 186.969 149.293 219.469 1.00 17.52 ? 187 PRO B CA  1 
ATOM 5505 C C   . PRO B 1 203 ? 187.771 150.546 219.782 1.00 17.52 ? 187 PRO B C   1 
ATOM 5506 O O   . PRO B 1 203 ? 187.246 151.659 219.844 1.00 17.52 ? 187 PRO B O   1 
ATOM 5507 C CB  . PRO B 1 203 ? 186.892 149.050 217.958 1.00 17.52 ? 187 PRO B CB  1 
ATOM 5508 C CG  . PRO B 1 203 ? 185.497 148.572 217.717 1.00 17.52 ? 187 PRO B CG  1 
ATOM 5509 C CD  . PRO B 1 203 ? 184.649 149.288 218.724 1.00 17.52 ? 187 PRO B CD  1 
ATOM 5510 N N   . HIS B 1 204 ? 189.074 150.343 219.987 1.00 18.72 ? 188 HIS B N   1 
ATOM 5511 C CA  . HIS B 1 204 ? 189.951 151.454 220.342 1.00 18.72 ? 188 HIS B CA  1 
ATOM 5512 C C   . HIS B 1 204 ? 189.994 152.517 219.250 1.00 18.72 ? 188 HIS B C   1 
ATOM 5513 O O   . HIS B 1 204 ? 190.154 153.705 219.551 1.00 18.72 ? 188 HIS B O   1 
ATOM 5514 C CB  . HIS B 1 204 ? 191.358 150.934 220.631 1.00 18.72 ? 188 HIS B CB  1 
ATOM 5515 C CG  . HIS B 1 204 ? 192.338 152.007 220.988 1.00 18.72 ? 188 HIS B CG  1 
ATOM 5516 N ND1 . HIS B 1 204 ? 193.089 152.674 220.044 1.00 18.72 ? 188 HIS B ND1 1 
ATOM 5517 C CD2 . HIS B 1 204 ? 192.688 152.531 222.186 1.00 18.72 ? 188 HIS B CD2 1 
ATOM 5518 C CE1 . HIS B 1 204 ? 193.861 153.561 220.645 1.00 18.72 ? 188 HIS B CE1 1 
ATOM 5519 N NE2 . HIS B 1 204 ? 193.638 153.494 221.945 1.00 18.72 ? 188 HIS B NE2 1 
ATOM 5520 N N   . ARG B 1 205 ? 189.858 152.113 217.986 1.00 16.10 ? 189 ARG B N   1 
ATOM 5521 C CA  . ARG B 1 205 ? 189.939 153.074 216.890 1.00 16.10 ? 189 ARG B CA  1 
ATOM 5522 C C   . ARG B 1 205 ? 188.712 153.980 216.844 1.00 16.10 ? 189 ARG B C   1 
ATOM 5523 O O   . ARG B 1 205 ? 188.844 155.201 216.702 1.00 16.10 ? 189 ARG B O   1 
ATOM 5524 C CB  . ARG B 1 205 ? 190.113 152.334 215.564 1.00 16.10 ? 189 ARG B CB  1 
ATOM 5525 C CG  . ARG B 1 205 ? 190.136 153.232 214.341 1.00 16.10 ? 189 ARG B CG  1 
ATOM 5526 C CD  . ARG B 1 205 ? 188.913 153.003 213.474 1.00 16.10 ? 189 ARG B CD  1 
ATOM 5527 N NE  . ARG B 1 205 ? 188.916 151.672 212.880 1.00 16.10 ? 189 ARG B NE  1 
ATOM 5528 C CZ  . ARG B 1 205 ? 189.258 151.412 211.626 1.00 16.10 ? 189 ARG B CZ  1 
ATOM 5529 N NH1 . ARG B 1 205 ? 189.635 152.374 210.800 1.00 16.10 ? 189 ARG B NH1 1 
ATOM 5530 N NH2 . ARG B 1 205 ? 189.221 150.157 211.190 1.00 16.10 ? 189 ARG B NH2 1 
ATOM 5531 N N   . LEU B 1 206 ? 187.513 153.402 216.959 1.00 15.09 ? 190 LEU B N   1 
ATOM 5532 C CA  . LEU B 1 206 ? 186.293 154.195 216.834 1.00 15.09 ? 190 LEU B CA  1 
ATOM 5533 C C   . LEU B 1 206 ? 186.160 155.210 217.964 1.00 15.09 ? 190 LEU B C   1 
ATOM 5534 O O   . LEU B 1 206 ? 185.772 156.360 217.727 1.00 15.09 ? 190 LEU B O   1 
ATOM 5535 C CB  . LEU B 1 206 ? 185.070 153.280 216.793 1.00 15.09 ? 190 LEU B CB  1 
ATOM 5536 C CG  . LEU B 1 206 ? 184.817 152.559 215.469 1.00 15.09 ? 190 LEU B CG  1 
ATOM 5537 C CD1 . LEU B 1 206 ? 183.589 151.669 215.566 1.00 15.09 ? 190 LEU B CD1 1 
ATOM 5538 C CD2 . LEU B 1 206 ? 184.666 153.567 214.342 1.00 15.09 ? 190 LEU B CD2 1 
ATOM 5539 N N   . LEU B 1 207 ? 186.476 154.807 219.197 1.00 14.46 ? 191 LEU B N   1 
ATOM 5540 C CA  . LEU B 1 207 ? 186.330 155.715 220.331 1.00 14.46 ? 191 LEU B CA  1 
ATOM 5541 C C   . LEU B 1 207 ? 187.264 156.913 220.228 1.00 14.46 ? 191 LEU B C   1 
ATOM 5542 O O   . LEU B 1 207 ? 186.960 157.982 220.769 1.00 14.46 ? 191 LEU B O   1 
ATOM 5543 C CB  . LEU B 1 207 ? 186.573 154.963 221.640 1.00 14.46 ? 191 LEU B CB  1 
ATOM 5544 C CG  . LEU B 1 207 ? 186.248 155.709 222.937 1.00 14.46 ? 191 LEU B CG  1 
ATOM 5545 C CD1 . LEU B 1 207 ? 184.763 155.997 223.049 1.00 14.46 ? 191 LEU B CD1 1 
ATOM 5546 C CD2 . LEU B 1 207 ? 186.734 154.924 224.145 1.00 14.46 ? 191 LEU B CD2 1 
ATOM 5547 N N   . THR B 1 208 ? 188.399 156.759 219.543 1.00 17.33 ? 192 THR B N   1 
ATOM 5548 C CA  . THR B 1 208 ? 189.343 157.865 219.422 1.00 17.33 ? 192 THR B CA  1 
ATOM 5549 C C   . THR B 1 208 ? 188.755 159.014 218.611 1.00 17.33 ? 192 THR B C   1 
ATOM 5550 O O   . THR B 1 208 ? 188.923 160.186 218.968 1.00 17.33 ? 192 THR B O   1 
ATOM 5551 C CB  . THR B 1 208 ? 190.646 157.375 218.789 1.00 17.33 ? 192 THR B CB  1 
ATOM 5552 O OG1 . THR B 1 208 ? 191.129 156.235 219.510 1.00 17.33 ? 192 THR B OG1 1 
ATOM 5553 C CG2 . THR B 1 208 ? 191.700 158.471 218.824 1.00 17.33 ? 192 THR B CG2 1 
ATOM 5554 N N   . ASP B 1 209 ? 188.059 158.699 217.516 1.00 14.84 ? 193 ASP B N   1 
ATOM 5555 C CA  . ASP B 1 209 ? 187.568 159.741 216.619 1.00 14.84 ? 193 ASP B CA  1 
ATOM 5556 C C   . ASP B 1 209 ? 186.367 160.490 217.184 1.00 14.84 ? 193 ASP B C   1 
ATOM 5557 O O   . ASP B 1 209 ? 186.268 161.709 217.004 1.00 14.84 ? 193 ASP B O   1 
ATOM 5558 C CB  . ASP B 1 209 ? 187.212 159.140 215.259 1.00 14.84 ? 193 ASP B CB  1 
ATOM 5559 C CG  . ASP B 1 209 ? 188.410 158.521 214.565 1.00 14.84 ? 193 ASP B CG  1 
ATOM 5560 O OD1 . ASP B 1 209 ? 189.506 159.115 214.629 1.00 14.84 ? 193 ASP B OD1 1 
ATOM 5561 O OD2 . ASP B 1 209 ? 188.255 157.444 213.954 1.00 14.84 ? 193 ASP B OD2 1 
ATOM 5562 N N   . ILE B 1 210 ? 185.445 159.796 217.853 1.00 12.46 ? 194 ILE B N   1 
ATOM 5563 C CA  . ILE B 1 210 ? 184.250 160.473 218.350 1.00 12.46 ? 194 ILE B CA  1 
ATOM 5564 C C   . ILE B 1 210 ? 184.581 161.400 219.517 1.00 12.46 ? 194 ILE B C   1 
ATOM 5565 O O   . ILE B 1 210 ? 183.919 162.427 219.700 1.00 12.46 ? 194 ILE B O   1 
ATOM 5566 C CB  . ILE B 1 210 ? 183.159 159.450 218.720 1.00 12.46 ? 194 ILE B CB  1 
ATOM 5567 C CG1 . ILE B 1 210 ? 183.304 158.970 220.165 1.00 12.46 ? 194 ILE B CG1 1 
ATOM 5568 C CG2 . ILE B 1 210 ? 183.183 158.273 217.760 1.00 12.46 ? 194 ILE B CG2 1 
ATOM 5569 C CD1 . ILE B 1 210 ? 182.064 158.295 220.704 1.00 12.46 ? 194 ILE B CD1 1 
ATOM 5570 N N   . ILE B 1 211 ? 185.589 161.062 220.324 1.00 13.35 ? 195 ILE B N   1 
ATOM 5571 C CA  . ILE B 1 211 ? 185.967 161.926 221.438 1.00 13.35 ? 195 ILE B CA  1 
ATOM 5572 C C   . ILE B 1 211 ? 186.638 163.197 220.931 1.00 13.35 ? 195 ILE B C   1 
ATOM 5573 O O   . ILE B 1 211 ? 186.322 164.304 221.382 1.00 13.35 ? 195 ILE B O   1 
ATOM 5574 C CB  . ILE B 1 211 ? 186.869 161.160 222.423 1.00 13.35 ? 195 ILE B CB  1 
ATOM 5575 C CG1 . ILE B 1 211 ? 186.024 160.283 223.347 1.00 13.35 ? 195 ILE B CG1 1 
ATOM 5576 C CG2 . ILE B 1 211 ? 187.724 162.119 223.233 1.00 13.35 ? 195 ILE B CG2 1 
ATOM 5577 C CD1 . ILE B 1 211 ? 186.789 159.137 223.962 1.00 13.35 ? 195 ILE B CD1 1 
ATOM 5578 N N   . SER B 1 212 ? 187.561 163.063 219.980 1.00 13.65 ? 196 SER B N   1 
ATOM 5579 C CA  . SER B 1 212 ? 188.330 164.203 219.496 1.00 13.65 ? 196 SER B CA  1 
ATOM 5580 C C   . SER B 1 212 ? 187.580 164.970 218.415 1.00 13.65 ? 196 SER B C   1 
ATOM 5581 O O   . SER B 1 212 ? 188.100 165.167 217.312 1.00 13.65 ? 196 SER B O   1 
ATOM 5582 C CB  . SER B 1 212 ? 189.689 163.737 218.969 1.00 13.65 ? 196 SER B CB  1 
ATOM 5583 O OG  . SER B 1 212 ? 190.128 164.549 217.894 1.00 13.65 ? 196 SER B OG  1 
ATOM 5584 N N   . ASP B 1 213 ? 186.357 165.409 218.718 1.00 14.92 ? 197 ASP B N   1 
ATOM 5585 C CA  . ASP B 1 213 ? 185.589 166.196 217.761 1.00 14.92 ? 197 ASP B CA  1 
ATOM 5586 C C   . ASP B 1 213 ? 184.827 167.342 218.417 1.00 14.92 ? 197 ASP B C   1 
ATOM 5587 O O   . ASP B 1 213 ? 184.004 167.979 217.747 1.00 14.92 ? 197 ASP B O   1 
ATOM 5588 C CB  . ASP B 1 213 ? 184.612 165.302 216.986 1.00 14.92 ? 197 ASP B CB  1 
ATOM 5589 C CG  . ASP B 1 213 ? 184.328 165.825 215.591 1.00 14.92 ? 197 ASP B CG  1 
ATOM 5590 O OD1 . ASP B 1 213 ? 184.971 166.815 215.185 1.00 14.92 ? 197 ASP B OD1 1 
ATOM 5591 O OD2 . ASP B 1 213 ? 183.462 165.250 214.901 1.00 14.92 ? 197 ASP B OD2 1 
ATOM 5592 N N   . GLY B 1 214 ? 185.068 167.628 219.694 1.00 14.08 ? 198 GLY B N   1 
ATOM 5593 C CA  . GLY B 1 214 ? 184.380 168.719 220.354 1.00 14.08 ? 198 GLY B CA  1 
ATOM 5594 C C   . GLY B 1 214 ? 183.111 168.299 221.065 1.00 14.08 ? 198 GLY B C   1 
ATOM 5595 O O   . GLY B 1 214 ? 182.044 168.876 220.836 1.00 14.08 ? 198 GLY B O   1 
ATOM 5596 N N   . VAL B 1 215 ? 183.212 167.288 221.922 1.00 17.33 ? 199 VAL B N   1 
ATOM 5597 C CA  . VAL B 1 215 ? 182.090 166.839 222.741 1.00 17.33 ? 199 VAL B CA  1 
ATOM 5598 C C   . VAL B 1 215 ? 181.715 167.966 223.698 1.00 17.33 ? 199 VAL B C   1 
ATOM 5599 O O   . VAL B 1 215 ? 182.606 168.588 224.295 1.00 17.33 ? 199 VAL B O   1 
ATOM 5600 C CB  . VAL B 1 215 ? 182.442 165.540 223.487 1.00 17.33 ? 199 VAL B CB  1 
ATOM 5601 C CG1 . VAL B 1 215 ? 183.809 165.657 224.137 1.00 17.33 ? 199 VAL B CG1 1 
ATOM 5602 C CG2 . VAL B 1 215 ? 181.383 165.201 224.524 1.00 17.33 ? 199 VAL B CG2 1 
ATOM 5603 N N   . PRO B 1 216 ? 180.430 168.277 223.863 1.00 19.16 ? 200 PRO B N   1 
ATOM 5604 C CA  . PRO B 1 216 ? 180.049 169.396 224.733 1.00 19.16 ? 200 PRO B CA  1 
ATOM 5605 C C   . PRO B 1 216 ? 180.466 169.172 226.179 1.00 19.16 ? 200 PRO B C   1 
ATOM 5606 O O   . PRO B 1 216 ? 180.490 168.046 226.681 1.00 19.16 ? 200 PRO B O   1 
ATOM 5607 C CB  . PRO B 1 216 ? 178.522 169.451 224.596 1.00 19.16 ? 200 PRO B CB  1 
ATOM 5608 C CG  . PRO B 1 216 ? 178.231 168.758 223.304 1.00 19.16 ? 200 PRO B CG  1 
ATOM 5609 C CD  . PRO B 1 216 ? 179.263 167.683 223.191 1.00 19.16 ? 200 PRO B CD  1 
ATOM 5610 N N   . CYS B 1 217 ? 180.800 170.280 226.848 1.00 21.99 ? 201 CYS B N   1 
ATOM 5611 C CA  . CYS B 1 217 ? 181.281 170.220 228.223 1.00 21.99 ? 201 CYS B CA  1 
ATOM 5612 C C   . CYS B 1 217 ? 180.213 169.749 229.200 1.00 21.99 ? 201 CYS B C   1 
ATOM 5613 O O   . CYS B 1 217 ? 180.556 169.248 230.277 1.00 21.99 ? 201 CYS B O   1 
ATOM 5614 C CB  . CYS B 1 217 ? 181.803 171.591 228.656 1.00 21.99 ? 201 CYS B CB  1 
ATOM 5615 S SG  . CYS B 1 217 ? 183.306 172.125 227.807 1.00 21.99 ? 201 CYS B SG  1 
ATOM 5616 N N   . SER B 1 218 ? 178.935 169.897 228.857 1.00 19.15 ? 202 SER B N   1 
ATOM 5617 C CA  . SER B 1 218 ? 177.859 169.494 229.752 1.00 19.15 ? 202 SER B CA  1 
ATOM 5618 C C   . SER B 1 218 ? 177.585 167.996 229.717 1.00 19.15 ? 202 SER B C   1 
ATOM 5619 O O   . SER B 1 218 ? 176.783 167.512 230.522 1.00 19.15 ? 202 SER B O   1 
ATOM 5620 C CB  . SER B 1 218 ? 176.577 170.257 229.410 1.00 19.15 ? 202 SER B CB  1 
ATOM 5621 O OG  . SER B 1 218 ? 175.474 169.753 230.143 1.00 19.15 ? 202 SER B OG  1 
ATOM 5622 N N   . GLN B 1 219 ? 178.225 167.257 228.812 1.00 17.95 ? 203 GLN B N   1 
ATOM 5623 C CA  . GLN B 1 219 ? 178.023 165.821 228.686 1.00 17.95 ? 203 GLN B CA  1 
ATOM 5624 C C   . GLN B 1 219 ? 179.058 165.011 229.456 1.00 17.95 ? 203 GLN B C   1 
ATOM 5625 O O   . GLN B 1 219 ? 179.062 163.780 229.357 1.00 17.95 ? 203 GLN B O   1 
ATOM 5626 C CB  . GLN B 1 219 ? 178.033 165.420 227.210 1.00 17.95 ? 203 GLN B CB  1 
ATOM 5627 C CG  . GLN B 1 219 ? 177.216 166.341 226.322 1.00 17.95 ? 203 GLN B CG  1 
ATOM 5628 C CD  . GLN B 1 219 ? 175.723 166.140 226.488 1.00 17.95 ? 203 GLN B CD  1 
ATOM 5629 O OE1 . GLN B 1 219 ? 175.279 165.135 227.042 1.00 17.95 ? 203 GLN B OE1 1 
ATOM 5630 N NE2 . GLN B 1 219 ? 174.940 167.097 226.006 1.00 17.95 ? 203 GLN B NE2 1 
ATOM 5631 N N   . ASN B 1 220 ? 179.935 165.676 230.213 1.00 18.87 ? 204 ASN B N   1 
ATOM 5632 C CA  . ASN B 1 220 ? 180.967 165.041 231.027 1.00 18.87 ? 204 ASN B CA  1 
ATOM 5633 C C   . ASN B 1 220 ? 181.878 164.167 230.173 1.00 18.87 ? 204 ASN B C   1 
ATOM 5634 O O   . ASN B 1 220 ? 181.831 162.934 230.277 1.00 18.87 ? 204 ASN B O   1 
ATOM 5635 C CB  . ASN B 1 220 ? 180.338 164.215 232.151 1.00 18.87 ? 204 ASN B CB  1 
ATOM 5636 C CG  . ASN B 1 220 ? 179.509 165.058 233.098 1.00 18.87 ? 204 ASN B CG  1 
ATOM 5637 O OD1 . ASN B 1 220 ? 178.299 165.202 232.923 1.00 18.87 ? 204 ASN B OD1 1 
ATOM 5638 N ND2 . ASN B 1 220 ? 180.157 165.621 234.111 1.00 18.87 ? 204 ASN B ND2 1 
ATOM 5639 N N   . PRO B 1 221 ? 182.709 164.761 229.312 1.00 20.48 ? 205 PRO B N   1 
ATOM 5640 C CA  . PRO B 1 221 ? 183.623 163.943 228.498 1.00 20.48 ? 205 PRO B CA  1 
ATOM 5641 C C   . PRO B 1 221 ? 184.624 163.149 229.317 1.00 20.48 ? 205 PRO B C   1 
ATOM 5642 O O   . PRO B 1 221 ? 185.020 162.053 228.900 1.00 20.48 ? 205 PRO B O   1 
ATOM 5643 C CB  . PRO B 1 221 ? 184.318 164.982 227.610 1.00 20.48 ? 205 PRO B CB  1 
ATOM 5644 C CG  . PRO B 1 221 ? 184.252 166.245 228.396 1.00 20.48 ? 205 PRO B CG  1 
ATOM 5645 C CD  . PRO B 1 221 ? 182.937 166.203 229.119 1.00 20.48 ? 205 PRO B CD  1 
ATOM 5646 N N   . THR B 1 222 ? 185.052 163.673 230.468 1.00 19.72 ? 206 THR B N   1 
ATOM 5647 C CA  . THR B 1 222 ? 186.031 162.967 231.288 1.00 19.72 ? 206 THR B CA  1 
ATOM 5648 C C   . THR B 1 222 ? 185.475 161.653 231.823 1.00 19.72 ? 206 THR B C   1 
ATOM 5649 O O   . THR B 1 222 ? 186.209 160.662 231.913 1.00 19.72 ? 206 THR B O   1 
ATOM 5650 C CB  . THR B 1 222 ? 186.490 163.857 232.444 1.00 19.72 ? 206 THR B CB  1 
ATOM 5651 O OG1 . THR B 1 222 ? 186.863 165.145 231.938 1.00 19.72 ? 206 THR B OG1 1 
ATOM 5652 C CG2 . THR B 1 222 ? 187.684 163.236 233.155 1.00 19.72 ? 206 THR B CG2 1 
ATOM 5653 N N   . GLU B 1 223 ? 184.189 161.625 232.180 1.00 20.20 ? 207 GLU B N   1 
ATOM 5654 C CA  . GLU B 1 223 ? 183.583 160.408 232.707 1.00 20.20 ? 207 GLU B CA  1 
ATOM 5655 C C   . GLU B 1 223 ? 183.558 159.277 231.687 1.00 20.20 ? 207 GLU B C   1 
ATOM 5656 O O   . GLU B 1 223 ? 183.568 158.107 232.084 1.00 20.20 ? 207 GLU B O   1 
ATOM 5657 C CB  . GLU B 1 223 ? 182.162 160.699 233.191 1.00 20.20 ? 207 GLU B CB  1 
ATOM 5658 C CG  . GLU B 1 223 ? 182.092 161.598 234.414 1.00 20.20 ? 207 GLU B CG  1 
ATOM 5659 C CD  . GLU B 1 223 ? 180.702 161.655 235.017 1.00 20.20 ? 207 GLU B CD  1 
ATOM 5660 O OE1 . GLU B 1 223 ? 179.718 161.522 234.260 1.00 20.20 ? 207 GLU B OE1 1 
ATOM 5661 O OE2 . GLU B 1 223 ? 180.594 161.831 236.249 1.00 20.20 ? 207 GLU B OE2 1 
ATOM 5662 N N   . ALA B 1 224 ? 183.529 159.597 230.391 1.00 18.39 ? 208 ALA B N   1 
ATOM 5663 C CA  . ALA B 1 224 ? 183.454 158.558 229.367 1.00 18.39 ? 208 ALA B CA  1 
ATOM 5664 C C   . ALA B 1 224 ? 184.670 157.640 229.418 1.00 18.39 ? 208 ALA B C   1 
ATOM 5665 O O   . ALA B 1 224 ? 184.537 156.413 229.344 1.00 18.39 ? 208 ALA B O   1 
ATOM 5666 C CB  . ALA B 1 224 ? 183.316 159.195 227.984 1.00 18.39 ? 208 ALA B CB  1 
ATOM 5667 N N   . ILE B 1 225 ? 185.865 158.218 229.544 1.00 19.37 ? 209 ILE B N   1 
ATOM 5668 C CA  . ILE B 1 225 ? 187.068 157.404 229.687 1.00 19.37 ? 209 ILE B CA  1 
ATOM 5669 C C   . ILE B 1 225 ? 187.054 156.665 231.019 1.00 19.37 ? 209 ILE B C   1 
ATOM 5670 O O   . ILE B 1 225 ? 187.535 155.530 231.121 1.00 19.37 ? 209 ILE B O   1 
ATOM 5671 C CB  . ILE B 1 225 ? 188.326 158.276 229.536 1.00 19.37 ? 209 ILE B CB  1 
ATOM 5672 C CG1 . ILE B 1 225 ? 188.130 159.308 228.426 1.00 19.37 ? 209 ILE B CG1 1 
ATOM 5673 C CG2 . ILE B 1 225 ? 189.543 157.409 229.249 1.00 19.37 ? 209 ILE B CG2 1 
ATOM 5674 C CD1 . ILE B 1 225 ? 189.260 160.303 228.320 1.00 19.37 ? 209 ILE B CD1 1 
ATOM 5675 N N   . GLU B 1 226 ? 186.507 157.299 232.060 1.00 22.92 ? 210 GLU B N   1 
ATOM 5676 C CA  . GLU B 1 226 ? 186.463 156.675 233.379 1.00 22.92 ? 210 GLU B CA  1 
ATOM 5677 C C   . GLU B 1 226 ? 185.617 155.407 233.375 1.00 22.92 ? 210 GLU B C   1 
ATOM 5678 O O   . GLU B 1 226 ? 185.799 154.538 234.236 1.00 22.92 ? 210 GLU B O   1 
ATOM 5679 C CB  . GLU B 1 226 ? 185.926 157.674 234.406 1.00 22.92 ? 210 GLU B CB  1 
ATOM 5680 C CG  . GLU B 1 226 ? 186.068 157.234 235.854 1.00 22.92 ? 210 GLU B CG  1 
ATOM 5681 C CD  . GLU B 1 226 ? 185.614 158.301 236.831 1.00 22.92 ? 210 GLU B CD  1 
ATOM 5682 O OE1 . GLU B 1 226 ? 184.604 158.978 236.546 1.00 22.92 ? 210 GLU B OE1 1 
ATOM 5683 O OE2 . GLU B 1 226 ? 186.268 158.463 237.883 1.00 22.92 ? 210 GLU B OE2 1 
ATOM 5684 N N   . ALA B 1 227 ? 184.692 155.281 232.419 1.00 21.23 ? 211 ALA B N   1 
ATOM 5685 C CA  . ALA B 1 227 ? 183.880 154.072 232.331 1.00 21.23 ? 211 ALA B CA  1 
ATOM 5686 C C   . ALA B 1 227 ? 184.742 152.848 232.049 1.00 21.23 ? 211 ALA B C   1 
ATOM 5687 O O   . ALA B 1 227 ? 184.527 151.779 232.632 1.00 21.23 ? 211 ALA B O   1 
ATOM 5688 C CB  . ALA B 1 227 ? 182.809 154.236 231.254 1.00 21.23 ? 211 ALA B CB  1 
ATOM 5689 N N   . TRP B 1 228 ? 185.723 152.984 231.153 1.00 18.73 ? 212 TRP B N   1 
ATOM 5690 C CA  . TRP B 1 228 ? 186.632 151.875 230.884 1.00 18.73 ? 212 TRP B CA  1 
ATOM 5691 C C   . TRP B 1 228 ? 187.583 151.633 232.049 1.00 18.73 ? 212 TRP B C   1 
ATOM 5692 O O   . TRP B 1 228 ? 188.002 150.493 232.279 1.00 18.73 ? 212 TRP B O   1 
ATOM 5693 C CB  . TRP B 1 228 ? 187.417 152.139 229.600 1.00 18.73 ? 212 TRP B CB  1 
ATOM 5694 C CG  . TRP B 1 228 ? 186.666 151.775 228.357 1.00 18.73 ? 212 TRP B CG  1 
ATOM 5695 C CD1 . TRP B 1 228 ? 185.347 151.438 228.267 1.00 18.73 ? 212 TRP B CD1 1 
ATOM 5696 C CD2 . TRP B 1 228 ? 187.188 151.708 227.025 1.00 18.73 ? 212 TRP B CD2 1 
ATOM 5697 N NE1 . TRP B 1 228 ? 185.015 151.167 226.962 1.00 18.73 ? 212 TRP B NE1 1 
ATOM 5698 C CE2 . TRP B 1 228 ? 186.129 151.325 226.179 1.00 18.73 ? 212 TRP B CE2 1 
ATOM 5699 C CE3 . TRP B 1 228 ? 188.449 151.935 226.465 1.00 18.73 ? 212 TRP B CE3 1 
ATOM 5700 C CZ2 . TRP B 1 228 ? 186.291 151.165 224.806 1.00 18.73 ? 212 TRP B CZ2 1 
ATOM 5701 C CZ3 . TRP B 1 228 ? 188.608 151.775 225.102 1.00 18.73 ? 212 TRP B CZ3 1 
ATOM 5702 C CH2 . TRP B 1 228 ? 187.535 151.393 224.287 1.00 18.73 ? 212 TRP B CH2 1 
ATOM 5703 N N   . ILE B 1 229 ? 187.940 152.689 232.785 1.00 21.80 ? 213 ILE B N   1 
ATOM 5704 C CA  . ILE B 1 229 ? 188.804 152.529 233.951 1.00 21.80 ? 213 ILE B CA  1 
ATOM 5705 C C   . ILE B 1 229 ? 188.108 151.699 235.023 1.00 21.80 ? 213 ILE B C   1 
ATOM 5706 O O   . ILE B 1 229 ? 188.710 150.798 235.618 1.00 21.80 ? 213 ILE B O   1 
ATOM 5707 C CB  . ILE B 1 229 ? 189.231 153.907 234.489 1.00 21.80 ? 213 ILE B CB  1 
ATOM 5708 C CG1 . ILE B 1 229 ? 190.132 154.620 233.479 1.00 21.80 ? 213 ILE B CG1 1 
ATOM 5709 C CG2 . ILE B 1 229 ? 189.938 153.765 235.828 1.00 21.80 ? 213 ILE B CG2 1 
ATOM 5710 C CD1 . ILE B 1 229 ? 190.613 155.978 233.943 1.00 21.80 ? 213 ILE B CD1 1 
ATOM 5711 N N   . ASN B 1 230 ? 186.832 151.982 235.280 1.00 24.08 ? 214 ASN B N   1 
ATOM 5712 C CA  . ASN B 1 230 ? 186.054 151.272 236.285 1.00 24.08 ? 214 ASN B CA  1 
ATOM 5713 C C   . ASN B 1 230 ? 185.343 150.046 235.721 1.00 24.08 ? 214 ASN B C   1 
ATOM 5714 O O   . ASN B 1 230 ? 184.318 149.628 236.272 1.00 24.08 ? 214 ASN B O   1 
ATOM 5715 C CB  . ASN B 1 230 ? 185.038 152.217 236.931 1.00 24.08 ? 214 ASN B CB  1 
ATOM 5716 C CG  . ASN B 1 230 ? 185.636 153.030 238.063 1.00 24.08 ? 214 ASN B CG  1 
ATOM 5717 O OD1 . ASN B 1 230 ? 185.921 154.217 237.907 1.00 24.08 ? 214 ASN B OD1 1 
ATOM 5718 N ND2 . ASN B 1 230 ? 185.828 152.392 239.212 1.00 24.08 ? 214 ASN B ND2 1 
ATOM 5719 N N   . PHE B 1 231 ? 185.859 149.470 234.632 1.00 25.09 ? 215 PHE B N   1 
ATOM 5720 C CA  . PHE B 1 231 ? 185.239 148.278 234.061 1.00 25.09 ? 215 PHE B CA  1 
ATOM 5721 C C   . PHE B 1 231 ? 185.289 147.109 235.035 1.00 25.09 ? 215 PHE B C   1 
ATOM 5722 O O   . PHE B 1 231 ? 184.315 146.358 235.167 1.00 25.09 ? 215 PHE B O   1 
ATOM 5723 C CB  . PHE B 1 231 ? 185.926 147.911 232.745 1.00 25.09 ? 215 PHE B CB  1 
ATOM 5724 C CG  . PHE B 1 231 ? 185.102 147.019 231.860 1.00 25.09 ? 215 PHE B CG  1 
ATOM 5725 C CD1 . PHE B 1 231 ? 184.195 147.558 230.963 1.00 25.09 ? 215 PHE B CD1 1 
ATOM 5726 C CD2 . PHE B 1 231 ? 185.235 145.642 231.926 1.00 25.09 ? 215 PHE B CD2 1 
ATOM 5727 C CE1 . PHE B 1 231 ? 183.437 146.739 230.147 1.00 25.09 ? 215 PHE B CE1 1 
ATOM 5728 C CE2 . PHE B 1 231 ? 184.478 144.819 231.114 1.00 25.09 ? 215 PHE B CE2 1 
ATOM 5729 C CZ  . PHE B 1 231 ? 183.578 145.368 230.223 1.00 25.09 ? 215 PHE B CZ  1 
ATOM 5730 N N   . ASN B 1 232 ? 186.413 146.936 235.725 1.00 24.41 ? 216 ASN B N   1 
ATOM 5731 C CA  . ASN B 1 232 ? 186.558 145.859 236.697 1.00 24.41 ? 216 ASN B CA  1 
ATOM 5732 C C   . ASN B 1 232 ? 186.824 146.417 238.092 1.00 24.41 ? 216 ASN B C   1 
ATOM 5733 O O   . ASN B 1 232 ? 186.222 147.410 238.500 1.00 24.41 ? 216 ASN B O   1 
ATOM 5734 C CB  . ASN B 1 232 ? 187.684 144.910 236.284 1.00 24.41 ? 216 ASN B CB  1 
ATOM 5735 C CG  . ASN B 1 232 ? 187.864 143.759 237.256 1.00 24.41 ? 216 ASN B CG  1 
ATOM 5736 O OD1 . ASN B 1 232 ? 187.208 142.724 237.138 1.00 24.41 ? 216 ASN B OD1 1 
ATOM 5737 N ND2 . ASN B 1 232 ? 188.760 143.934 238.221 1.00 24.41 ? 216 ASN B ND2 1 
ATOM 5738 N N   . GLU B 1 234 ? 194.387 144.129 233.248 1.00 29.53 ? 218 GLU B N   1 
ATOM 5739 C CA  . GLU B 1 234 ? 194.220 143.173 232.160 1.00 29.53 ? 218 GLU B CA  1 
ATOM 5740 C C   . GLU B 1 234 ? 194.852 143.693 230.872 1.00 29.53 ? 218 GLU B C   1 
ATOM 5741 O O   . GLU B 1 234 ? 195.895 144.346 230.901 1.00 29.53 ? 218 GLU B O   1 
ATOM 5742 C CB  . GLU B 1 234 ? 192.737 142.871 231.934 1.00 29.53 ? 218 GLU B CB  1 
ATOM 5743 C CG  . GLU B 1 234 ? 192.095 142.037 233.032 1.00 29.53 ? 218 GLU B CG  1 
ATOM 5744 C CD  . GLU B 1 234 ? 192.518 140.581 232.986 1.00 29.53 ? 218 GLU B CD  1 
ATOM 5745 O OE1 . GLU B 1 234 ? 193.049 140.144 231.943 1.00 29.53 ? 218 GLU B OE1 1 
ATOM 5746 O OE2 . GLU B 1 234 ? 192.317 139.871 233.993 1.00 29.53 ? 218 GLU B OE2 1 
ATOM 5747 N N   . GLU B 1 235 ? 194.211 143.397 229.742 1.00 25.02 ? 219 GLU B N   1 
ATOM 5748 C CA  . GLU B 1 235 ? 194.697 143.832 228.439 1.00 25.02 ? 219 GLU B CA  1 
ATOM 5749 C C   . GLU B 1 235 ? 194.170 145.198 228.028 1.00 25.02 ? 219 GLU B C   1 
ATOM 5750 O O   . GLU B 1 235 ? 194.925 145.997 227.466 1.00 25.02 ? 219 GLU B O   1 
ATOM 5751 C CB  . GLU B 1 235 ? 194.321 142.804 227.366 1.00 25.02 ? 219 GLU B CB  1 
ATOM 5752 C CG  . GLU B 1 235 ? 194.839 143.130 225.972 1.00 25.02 ? 219 GLU B CG  1 
ATOM 5753 C CD  . GLU B 1 235 ? 196.353 143.172 225.905 1.00 25.02 ? 219 GLU B CD  1 
ATOM 5754 O OE1 . GLU B 1 235 ? 197.005 142.367 226.602 1.00 25.02 ? 219 GLU B OE1 1 
ATOM 5755 O OE2 . GLU B 1 235 ? 196.891 144.011 225.152 1.00 25.02 ? 219 GLU B OE2 1 
ATOM 5756 N N   . ARG B 1 236 ? 192.898 145.487 228.299 1.00 24.94 ? 220 ARG B N   1 
ATOM 5757 C CA  . ARG B 1 236 ? 192.296 146.763 227.940 1.00 24.94 ? 220 ARG B CA  1 
ATOM 5758 C C   . ARG B 1 236 ? 192.524 147.849 228.983 1.00 24.94 ? 220 ARG B C   1 
ATOM 5759 O O   . ARG B 1 236 ? 192.243 149.019 228.704 1.00 24.94 ? 220 ARG B O   1 
ATOM 5760 C CB  . ARG B 1 236 ? 190.790 146.588 227.712 1.00 24.94 ? 220 ARG B CB  1 
ATOM 5761 C CG  . ARG B 1 236 ? 190.055 145.982 228.896 1.00 24.94 ? 220 ARG B CG  1 
ATOM 5762 C CD  . ARG B 1 236 ? 188.622 145.632 228.536 1.00 24.94 ? 220 ARG B CD  1 
ATOM 5763 N NE  . ARG B 1 236 ? 188.335 144.221 228.765 1.00 24.94 ? 220 ARG B NE  1 
ATOM 5764 C CZ  . ARG B 1 236 ? 187.133 143.672 228.647 1.00 24.94 ? 220 ARG B CZ  1 
ATOM 5765 N NH1 . ARG B 1 236 ? 186.078 144.389 228.296 1.00 24.94 ? 220 ARG B NH1 1 
ATOM 5766 N NH2 . ARG B 1 236 ? 186.988 142.372 228.885 1.00 24.94 ? 220 ARG B NH2 1 
ATOM 5767 N N   . GLU B 1 237 ? 193.023 147.496 230.166 1.00 26.73 ? 221 GLU B N   1 
ATOM 5768 C CA  . GLU B 1 237 ? 193.261 148.471 231.222 1.00 26.73 ? 221 GLU B CA  1 
ATOM 5769 C C   . GLU B 1 237 ? 194.612 149.161 231.102 1.00 26.73 ? 221 GLU B C   1 
ATOM 5770 O O   . GLU B 1 237 ? 194.903 150.058 231.901 1.00 26.73 ? 221 GLU B O   1 
ATOM 5771 C CB  . GLU B 1 237 ? 193.146 147.799 232.593 1.00 26.73 ? 221 GLU B CB  1 
ATOM 5772 C CG  . GLU B 1 237 ? 191.916 146.918 232.752 1.00 26.73 ? 221 GLU B CG  1 
ATOM 5773 C CD  . GLU B 1 237 ? 190.637 147.719 232.902 1.00 26.73 ? 221 GLU B CD  1 
ATOM 5774 O OE1 . GLU B 1 237 ? 190.720 148.928 233.205 1.00 26.73 ? 221 GLU B OE1 1 
ATOM 5775 O OE2 . GLU B 1 237 ? 189.547 147.139 232.715 1.00 26.73 ? 221 GLU B OE2 1 
ATOM 5776 N N   . ALA B 1 238 ? 195.442 148.767 230.133 1.00 24.12 ? 222 ALA B N   1 
ATOM 5777 C CA  . ALA B 1 238 ? 196.735 149.414 229.948 1.00 24.12 ? 222 ALA B CA  1 
ATOM 5778 C C   . ALA B 1 238 ? 196.599 150.845 229.445 1.00 24.12 ? 222 ALA B C   1 
ATOM 5779 O O   . ALA B 1 238 ? 197.526 151.641 229.622 1.00 24.12 ? 222 ALA B O   1 
ATOM 5780 C CB  . ALA B 1 238 ? 197.597 148.602 228.981 1.00 24.12 ? 222 ALA B CB  1 
ATOM 5781 N N   . PHE B 1 239 ? 195.473 151.186 228.824 1.00 24.78 ? 223 PHE B N   1 
ATOM 5782 C CA  . PHE B 1 239 ? 195.246 152.537 228.318 1.00 24.78 ? 223 PHE B CA  1 
ATOM 5783 C C   . PHE B 1 239 ? 194.933 153.457 229.490 1.00 24.78 ? 223 PHE B C   1 
ATOM 5784 O O   . PHE B 1 239 ? 193.791 153.535 229.949 1.00 24.78 ? 223 PHE B O   1 
ATOM 5785 C CB  . PHE B 1 239 ? 194.111 152.541 227.300 1.00 24.78 ? 223 PHE B CB  1 
ATOM 5786 C CG  . PHE B 1 239 ? 194.385 151.707 226.082 1.00 24.78 ? 223 PHE B CG  1 
ATOM 5787 C CD1 . PHE B 1 239 ? 195.116 152.221 225.024 1.00 24.78 ? 223 PHE B CD1 1 
ATOM 5788 C CD2 . PHE B 1 239 ? 193.905 150.412 225.991 1.00 24.78 ? 223 PHE B CD2 1 
ATOM 5789 C CE1 . PHE B 1 239 ? 195.369 151.457 223.901 1.00 24.78 ? 223 PHE B CE1 1 
ATOM 5790 C CE2 . PHE B 1 239 ? 194.153 149.643 224.870 1.00 24.78 ? 223 PHE B CE2 1 
ATOM 5791 C CZ  . PHE B 1 239 ? 194.885 150.166 223.824 1.00 24.78 ? 223 PHE B CZ  1 
ATOM 5792 N N   . ALA B 1 240 ? 195.951 154.161 229.984 1.00 25.22 ? 224 ALA B N   1 
ATOM 5793 C CA  . ALA B 1 240 ? 195.791 155.098 231.088 1.00 25.22 ? 224 ALA B CA  1 
ATOM 5794 C C   . ALA B 1 240 ? 196.012 156.538 230.644 1.00 25.22 ? 224 ALA B C   1 
ATOM 5795 O O   . ALA B 1 240 ? 195.137 157.387 230.834 1.00 25.22 ? 224 ALA B O   1 
ATOM 5796 C CB  . ALA B 1 240 ? 196.749 154.735 232.231 1.00 25.22 ? 224 ALA B CB  1 
ATOM 5797 N N   . GLU B 1 241 ? 197.170 156.838 230.052 1.00 28.86 ? 225 GLU B N   1 
ATOM 5798 C CA  . GLU B 1 241 ? 197.423 158.182 229.549 1.00 28.86 ? 225 GLU B CA  1 
ATOM 5799 C C   . GLU B 1 241 ? 196.807 158.409 228.176 1.00 28.86 ? 225 GLU B C   1 
ATOM 5800 O O   . GLU B 1 241 ? 196.567 159.562 227.801 1.00 28.86 ? 225 GLU B O   1 
ATOM 5801 C CB  . GLU B 1 241 ? 198.928 158.449 229.495 1.00 28.86 ? 225 GLU B CB  1 
ATOM 5802 C CG  . GLU B 1 241 ? 199.671 158.073 230.767 1.00 28.86 ? 225 GLU B CG  1 
ATOM 5803 C CD  . GLU B 1 241 ? 201.177 158.172 230.614 1.00 28.86 ? 225 GLU B CD  1 
ATOM 5804 O OE1 . GLU B 1 241 ? 201.640 158.542 229.514 1.00 28.86 ? 225 GLU B OE1 1 
ATOM 5805 O OE2 . GLU B 1 241 ? 201.896 157.880 231.592 1.00 28.86 ? 225 GLU B OE2 1 
ATOM 5806 N N   . SER B 1 242 ? 196.548 157.344 227.424 1.00 23.93 ? 226 SER B N   1 
ATOM 5807 C CA  . SER B 1 242 ? 195.979 157.481 226.092 1.00 23.93 ? 226 SER B CA  1 
ATOM 5808 C C   . SER B 1 242 ? 194.518 157.911 226.167 1.00 23.93 ? 226 SER B C   1 
ATOM 5809 O O   . SER B 1 242 ? 193.849 157.748 227.192 1.00 23.93 ? 226 SER B O   1 
ATOM 5810 C CB  . SER B 1 242 ? 196.100 156.166 225.323 1.00 23.93 ? 226 SER B CB  1 
ATOM 5811 O OG  . SER B 1 242 ? 195.895 155.057 226.180 1.00 23.93 ? 226 SER B OG  1 
ATOM 5812 N N   . LEU B 1 243 ? 194.035 158.483 225.064 1.00 21.36 ? 227 LEU B N   1 
ATOM 5813 C CA  . LEU B 1 243 ? 192.664 158.959 224.890 1.00 21.36 ? 227 LEU B CA  1 
ATOM 5814 C C   . LEU B 1 243 ? 192.321 160.133 225.800 1.00 21.36 ? 227 LEU B C   1 
ATOM 5815 O O   . LEU B 1 243 ? 191.191 160.632 225.756 1.00 21.36 ? 227 LEU B O   1 
ATOM 5816 C CB  . LEU B 1 243 ? 191.632 157.835 225.087 1.00 21.36 ? 227 LEU B CB  1 
ATOM 5817 C CG  . LEU B 1 243 ? 191.394 156.769 224.007 1.00 21.36 ? 227 LEU B CG  1 
ATOM 5818 C CD1 . LEU B 1 243 ? 192.664 156.339 223.285 1.00 21.36 ? 227 LEU B CD1 1 
ATOM 5819 C CD2 . LEU B 1 243 ? 190.686 155.560 224.608 1.00 21.36 ? 227 LEU B CD2 1 
ATOM 5820 N N   . ARG B 1 244 ? 193.265 160.594 226.616 1.00 24.92 ? 228 ARG B N   1 
ATOM 5821 C CA  . ARG B 1 244 ? 193.061 161.743 227.489 1.00 24.92 ? 228 ARG B CA  1 
ATOM 5822 C C   . ARG B 1 244 ? 193.680 163.019 226.946 1.00 24.92 ? 228 ARG B C   1 
ATOM 5823 O O   . ARG B 1 244 ? 193.111 164.099 227.123 1.00 24.92 ? 228 ARG B O   1 
ATOM 5824 C CB  . ARG B 1 244 ? 193.634 161.457 228.883 1.00 24.92 ? 228 ARG B CB  1 
ATOM 5825 C CG  . ARG B 1 244 ? 193.265 162.492 229.933 1.00 24.92 ? 228 ARG B CG  1 
ATOM 5826 C CD  . ARG B 1 244 ? 193.694 162.046 231.321 1.00 24.92 ? 228 ARG B CD  1 
ATOM 5827 N NE  . ARG B 1 244 ? 195.143 162.062 231.475 1.00 24.92 ? 228 ARG B NE  1 
ATOM 5828 C CZ  . ARG B 1 244 ? 195.785 161.677 232.569 1.00 24.92 ? 228 ARG B CZ  1 
ATOM 5829 N NH1 . ARG B 1 244 ? 195.134 161.235 233.633 1.00 24.92 ? 228 ARG B NH1 1 
ATOM 5830 N NH2 . ARG B 1 244 ? 197.113 161.736 232.598 1.00 24.92 ? 228 ARG B NH2 1 
ATOM 5831 N N   . THR B 1 245 ? 194.835 162.922 226.285 1.00 23.22 ? 229 THR B N   1 
ATOM 5832 C CA  . THR B 1 245 ? 195.445 164.095 225.673 1.00 23.22 ? 229 THR B CA  1 
ATOM 5833 C C   . THR B 1 245 ? 194.706 164.540 224.419 1.00 23.22 ? 229 THR B C   1 
ATOM 5834 O O   . THR B 1 245 ? 194.765 165.723 224.067 1.00 23.22 ? 229 THR B O   1 
ATOM 5835 C CB  . THR B 1 245 ? 196.910 163.815 225.334 1.00 23.22 ? 229 THR B CB  1 
ATOM 5836 O OG1 . THR B 1 245 ? 196.997 163.244 224.022 1.00 23.22 ? 229 THR B OG1 1 
ATOM 5837 C CG2 . THR B 1 245 ? 197.515 162.848 226.341 1.00 23.22 ? 229 THR B CG2 1 
ATOM 5838 N N   . SER B 1 246 ? 194.013 163.626 223.742 1.00 19.74 ? 230 SER B N   1 
ATOM 5839 C CA  . SER B 1 246 ? 193.289 163.949 222.521 1.00 19.74 ? 230 SER B CA  1 
ATOM 5840 C C   . SER B 1 246 ? 191.883 164.474 222.777 1.00 19.74 ? 230 SER B C   1 
ATOM 5841 O O   . SER B 1 246 ? 191.229 164.929 221.833 1.00 19.74 ? 230 SER B O   1 
ATOM 5842 C CB  . SER B 1 246 ? 193.213 162.719 221.611 1.00 19.74 ? 230 SER B CB  1 
ATOM 5843 O OG  . SER B 1 246 ? 192.701 161.599 222.312 1.00 19.74 ? 230 SER B OG  1 
ATOM 5844 N N   . LEU B 1 247 ? 191.404 164.423 224.018 1.00 18.17 ? 231 LEU B N   1 
ATOM 5845 C CA  . LEU B 1 247 ? 190.069 164.919 224.321 1.00 18.17 ? 231 LEU B CA  1 
ATOM 5846 C C   . LEU B 1 247 ? 190.064 166.442 224.301 1.00 18.17 ? 231 LEU B C   1 
ATOM 5847 O O   . LEU B 1 247 ? 190.901 167.086 224.941 1.00 18.17 ? 231 LEU B O   1 
ATOM 5848 C CB  . LEU B 1 247 ? 189.605 164.395 225.683 1.00 18.17 ? 231 LEU B CB  1 
ATOM 5849 C CG  . LEU B 1 247 ? 188.117 164.445 226.054 1.00 18.17 ? 231 LEU B CG  1 
ATOM 5850 C CD1 . LEU B 1 247 ? 187.843 163.513 227.221 1.00 18.17 ? 231 LEU B CD1 1 
ATOM 5851 C CD2 . LEU B 1 247 ? 187.650 165.852 226.402 1.00 18.17 ? 231 LEU B CD2 1 
ATOM 5852 N N   . LYS B 1 248 ? 189.117 167.016 223.564 1.00 19.33 ? 232 LYS B N   1 
ATOM 5853 C CA  . LYS B 1 248 ? 188.929 168.459 223.496 1.00 19.33 ? 232 LYS B CA  1 
ATOM 5854 C C   . LYS B 1 248 ? 187.485 168.773 223.853 1.00 19.33 ? 232 LYS B C   1 
ATOM 5855 O O   . LYS B 1 248 ? 186.559 168.272 223.205 1.00 19.33 ? 232 LYS B O   1 
ATOM 5856 C CB  . LYS B 1 248 ? 189.273 168.996 222.105 1.00 19.33 ? 232 LYS B CB  1 
ATOM 5857 C CG  . LYS B 1 248 ? 189.442 170.504 222.047 1.00 19.33 ? 232 LYS B CG  1 
ATOM 5858 C CD  . LYS B 1 248 ? 190.389 170.908 220.930 1.00 19.33 ? 232 LYS B CD  1 
ATOM 5859 C CE  . LYS B 1 248 ? 189.637 171.160 219.634 1.00 19.33 ? 232 LYS B CE  1 
ATOM 5860 N NZ  . LYS B 1 248 ? 188.860 172.428 219.682 1.00 19.33 ? 232 LYS B NZ  1 
ATOM 5861 N N   . GLU B 1 249 ? 187.294 169.600 224.875 1.00 20.16 ? 233 GLU B N   1 
ATOM 5862 C CA  . GLU B 1 249 ? 185.966 169.955 225.356 1.00 20.16 ? 233 GLU B CA  1 
ATOM 5863 C C   . GLU B 1 249 ? 185.653 171.391 224.953 1.00 20.16 ? 233 GLU B C   1 
ATOM 5864 O O   . GLU B 1 249 ? 186.467 172.296 225.167 1.00 20.16 ? 233 GLU B O   1 
ATOM 5865 C CB  . GLU B 1 249 ? 185.867 169.769 226.872 1.00 20.16 ? 233 GLU B CB  1 
ATOM 5866 C CG  . GLU B 1 249 ? 186.798 170.650 227.694 1.00 20.16 ? 233 GLU B CG  1 
ATOM 5867 C CD  . GLU B 1 249 ? 186.407 170.702 229.157 1.00 20.16 ? 233 GLU B CD  1 
ATOM 5868 O OE1 . GLU B 1 249 ? 186.829 171.650 229.854 1.00 20.16 ? 233 GLU B OE1 1 
ATOM 5869 O OE2 . GLU B 1 249 ? 185.676 169.797 229.610 1.00 20.16 ? 233 GLU B OE2 1 
ATOM 5870 N N   . ILE B 1 250 ? 184.490 171.590 224.337 1.00 18.40 ? 234 ILE B N   1 
ATOM 5871 C CA  . ILE B 1 250 ? 184.009 172.911 223.949 1.00 18.40 ? 234 ILE B CA  1 
ATOM 5872 C C   . ILE B 1 250 ? 182.599 173.081 224.499 1.00 18.40 ? 234 ILE B C   1 
ATOM 5873 O O   . ILE B 1 250 ? 181.809 172.129 224.510 1.00 18.40 ? 234 ILE B O   1 
ATOM 5874 C CB  . ILE B 1 250 ? 184.055 173.120 222.420 1.00 18.40 ? 234 ILE B CB  1 
ATOM 5875 C CG1 . ILE B 1 250 ? 182.773 172.636 221.741 1.00 18.40 ? 234 ILE B CG1 1 
ATOM 5876 C CG2 . ILE B 1 250 ? 185.271 172.431 221.809 1.00 18.40 ? 234 ILE B CG2 1 
ATOM 5877 C CD1 . ILE B 1 250 ? 182.594 173.167 220.341 1.00 18.40 ? 234 ILE B CD1 1 
ATOM 5878 N N   . GLY B 1 251 ? 182.310 174.271 225.020 1.00 21.35 ? 235 GLY B N   1 
ATOM 5879 C CA  . GLY B 1 251 ? 180.974 174.535 225.524 1.00 21.35 ? 235 GLY B CA  1 
ATOM 5880 C C   . GLY B 1 251 ? 179.959 174.571 224.395 1.00 21.35 ? 235 GLY B C   1 
ATOM 5881 O O   . GLY B 1 251 ? 180.254 175.008 223.280 1.00 21.35 ? 235 GLY B O   1 
ATOM 5882 N N   . GLU B 1 252 ? 178.749 174.102 224.690 1.00 21.59 ? 236 GLU B N   1 
ATOM 5883 C CA  . GLU B 1 252 ? 177.687 174.113 223.694 1.00 21.59 ? 236 GLU B CA  1 
ATOM 5884 C C   . GLU B 1 252 ? 177.210 175.540 223.456 1.00 21.59 ? 236 GLU B C   1 
ATOM 5885 O O   . GLU B 1 252 ? 176.964 176.291 224.405 1.00 21.59 ? 236 GLU B O   1 
ATOM 5886 C CB  . GLU B 1 252 ? 176.525 173.228 224.143 1.00 21.59 ? 236 GLU B CB  1 
ATOM 5887 C CG  . GLU B 1 252 ? 175.356 173.205 223.169 1.00 21.59 ? 236 GLU B CG  1 
ATOM 5888 C CD  . GLU B 1 252 ? 174.447 172.009 223.375 1.00 21.59 ? 236 GLU B CD  1 
ATOM 5889 O OE1 . GLU B 1 252 ? 174.638 171.279 224.370 1.00 21.59 ? 236 GLU B OE1 1 
ATOM 5890 O OE2 . GLU B 1 252 ? 173.541 171.798 222.541 1.00 21.59 ? 236 GLU B OE2 1 
ATOM 5891 N N   . ASN B 1 253 ? 177.082 175.914 222.183 1.00 23.15 ? 237 ASN B N   1 
ATOM 5892 C CA  . ASN B 1 253 ? 176.668 177.258 221.814 1.00 23.15 ? 237 ASN B CA  1 
ATOM 5893 C C   . ASN B 1 253 ? 175.581 177.290 220.749 1.00 23.15 ? 237 ASN B C   1 
ATOM 5894 O O   . ASN B 1 253 ? 175.092 178.377 220.423 1.00 23.15 ? 237 ASN B O   1 
ATOM 5895 C CB  . ASN B 1 253 ? 177.875 178.076 221.329 1.00 23.15 ? 237 ASN B CB  1 
ATOM 5896 C CG  . ASN B 1 253 ? 178.736 177.315 220.338 1.00 23.15 ? 237 ASN B CG  1 
ATOM 5897 O OD1 . ASN B 1 253 ? 178.318 176.298 219.786 1.00 23.15 ? 237 ASN B OD1 1 
ATOM 5898 N ND2 . ASN B 1 253 ? 179.947 177.808 220.107 1.00 23.15 ? 237 ASN B ND2 1 
ATOM 5899 N N   . VAL B 1 254 ? 175.191 176.144 220.200 1.00 21.16 ? 238 VAL B N   1 
ATOM 5900 C CA  . VAL B 1 254 ? 174.154 176.082 219.176 1.00 21.16 ? 238 VAL B CA  1 
ATOM 5901 C C   . VAL B 1 254 ? 172.818 175.860 219.876 1.00 21.16 ? 238 VAL B C   1 
ATOM 5902 O O   . VAL B 1 254 ? 172.576 174.797 220.453 1.00 21.16 ? 238 VAL B O   1 
ATOM 5903 C CB  . VAL B 1 254 ? 174.437 174.977 218.152 1.00 21.16 ? 238 VAL B CB  1 
ATOM 5904 C CG1 . VAL B 1 254 ? 173.328 174.920 217.112 1.00 21.16 ? 238 VAL B CG1 1 
ATOM 5905 C CG2 . VAL B 1 254 ? 175.786 175.205 217.487 1.00 21.16 ? 238 VAL B CG2 1 
ATOM 5906 N N   . HIS B 1 255 ? 171.950 176.866 219.825 1.00 21.06 ? 239 HIS B N   1 
ATOM 5907 C CA  . HIS B 1 255 ? 170.639 176.800 220.457 1.00 21.06 ? 239 HIS B CA  1 
ATOM 5908 C C   . HIS B 1 255 ? 169.679 177.670 219.652 1.00 21.06 ? 239 HIS B C   1 
ATOM 5909 O O   . HIS B 1 255 ? 169.971 178.070 218.521 1.00 21.06 ? 239 HIS B O   1 
ATOM 5910 C CB  . HIS B 1 255 ? 170.729 177.218 221.931 1.00 21.06 ? 239 HIS B CB  1 
ATOM 5911 C CG  . HIS B 1 255 ? 171.605 178.408 222.171 1.00 21.06 ? 239 HIS B CG  1 
ATOM 5912 N ND1 . HIS B 1 255 ? 171.249 179.684 221.792 1.00 21.06 ? 239 HIS B ND1 1 
ATOM 5913 C CD2 . HIS B 1 255 ? 172.822 178.515 222.756 1.00 21.06 ? 239 HIS B CD2 1 
ATOM 5914 C CE1 . HIS B 1 255 ? 172.209 180.526 222.132 1.00 21.06 ? 239 HIS B CE1 1 
ATOM 5915 N NE2 . HIS B 1 255 ? 173.175 179.842 222.718 1.00 21.06 ? 239 HIS B NE2 1 
ATOM 5916 N N   . ILE B 1 256 ? 168.521 177.963 220.237 1.00 19.19 ? 240 ILE B N   1 
ATOM 5917 C CA  . ILE B 1 256 ? 167.472 178.728 219.572 1.00 19.19 ? 240 ILE B CA  1 
ATOM 5918 C C   . ILE B 1 256 ? 167.489 180.150 220.113 1.00 19.19 ? 240 ILE B C   1 
ATOM 5919 O O   . ILE B 1 256 ? 167.430 180.363 221.330 1.00 19.19 ? 240 ILE B O   1 
ATOM 5920 C CB  . ILE B 1 256 ? 166.091 178.087 219.776 1.00 19.19 ? 240 ILE B CB  1 
ATOM 5921 C CG1 . ILE B 1 256 ? 166.174 176.568 219.639 1.00 19.19 ? 240 ILE B CG1 1 
ATOM 5922 C CG2 . ILE B 1 256 ? 165.093 178.656 218.784 1.00 19.19 ? 240 ILE B CG2 1 
ATOM 5923 C CD1 . ILE B 1 256 ? 164.826 175.886 219.687 1.00 19.19 ? 240 ILE B CD1 1 
ATOM 5924 N N   . TYR B 1 257 ? 167.564 181.124 219.210 1.00 24.77 ? 241 TYR B N   1 
ATOM 5925 C CA  . TYR B 1 257 ? 167.434 182.522 219.591 1.00 24.77 ? 241 TYR B CA  1 
ATOM 5926 C C   . TYR B 1 257 ? 165.999 182.984 219.381 1.00 24.77 ? 241 TYR B C   1 
ATOM 5927 O O   . TYR B 1 257 ? 165.426 182.809 218.302 1.00 24.77 ? 241 TYR B O   1 
ATOM 5928 C CB  . TYR B 1 257 ? 168.392 183.393 218.779 1.00 24.77 ? 241 TYR B CB  1 
ATOM 5929 C CG  . TYR B 1 257 ? 169.641 183.795 219.532 1.00 24.77 ? 241 TYR B CG  1 
ATOM 5930 C CD1 . TYR B 1 257 ? 169.596 184.776 220.514 1.00 24.77 ? 241 TYR B CD1 1 
ATOM 5931 C CD2 . TYR B 1 257 ? 170.864 183.197 219.259 1.00 24.77 ? 241 TYR B CD2 1 
ATOM 5932 C CE1 . TYR B 1 257 ? 170.734 185.148 221.203 1.00 24.77 ? 241 TYR B CE1 1 
ATOM 5933 C CE2 . TYR B 1 257 ? 172.007 183.564 219.944 1.00 24.77 ? 241 TYR B CE2 1 
ATOM 5934 C CZ  . TYR B 1 257 ? 171.936 184.539 220.915 1.00 24.77 ? 241 TYR B CZ  1 
ATOM 5935 O OH  . TYR B 1 257 ? 173.070 184.907 221.599 1.00 24.77 ? 241 TYR B OH  1 
ATOM 5936 N N   . LEU B 1 258 ? 165.419 183.577 220.421 1.00 20.86 ? 242 LEU B N   1 
ATOM 5937 C CA  . LEU B 1 258 ? 164.020 183.979 220.419 1.00 20.86 ? 242 LEU B CA  1 
ATOM 5938 C C   . LEU B 1 258 ? 163.936 185.492 220.554 1.00 20.86 ? 242 LEU B C   1 
ATOM 5939 O O   . LEU B 1 258 ? 164.562 186.076 221.444 1.00 20.86 ? 242 LEU B O   1 
ATOM 5940 C CB  . LEU B 1 258 ? 163.255 183.283 221.552 1.00 20.86 ? 242 LEU B CB  1 
ATOM 5941 C CG  . LEU B 1 258 ? 161.731 183.143 221.469 1.00 20.86 ? 242 LEU B CG  1 
ATOM 5942 C CD1 . LEU B 1 258 ? 161.254 182.085 222.451 1.00 20.86 ? 242 LEU B CD1 1 
ATOM 5943 C CD2 . LEU B 1 258 ? 161.020 184.459 221.737 1.00 20.86 ? 242 LEU B CD2 1 
ATOM 5944 N N   . ILE B 1 259 ? 163.161 186.120 219.672 1.00 24.58 ? 243 ILE B N   1 
ATOM 5945 C CA  . ILE B 1 259 ? 162.966 187.565 219.665 1.00 24.58 ? 243 ILE B CA  1 
ATOM 5946 C C   . ILE B 1 259 ? 161.484 187.846 219.868 1.00 24.58 ? 243 ILE B C   1 
ATOM 5947 O O   . ILE B 1 259 ? 160.640 187.291 219.155 1.00 24.58 ? 243 ILE B O   1 
ATOM 5948 C CB  . ILE B 1 259 ? 163.465 188.201 218.355 1.00 24.58 ? 243 ILE B CB  1 
ATOM 5949 C CG1 . ILE B 1 259 ? 164.948 187.891 218.138 1.00 24.58 ? 243 ILE B CG1 1 
ATOM 5950 C CG2 . ILE B 1 259 ? 163.221 189.702 218.363 1.00 24.58 ? 243 ILE B CG2 1 
ATOM 5951 C CD1 . ILE B 1 259 ? 165.877 188.688 219.026 1.00 24.58 ? 243 ILE B CD1 1 
ATOM 5952 N N   . GLY B 1 260 ? 161.172 188.706 220.833 1.00 23.29 ? 244 GLY B N   1 
ATOM 5953 C CA  . GLY B 1 260 ? 159.792 189.039 221.126 1.00 23.29 ? 244 GLY B CA  1 
ATOM 5954 C C   . GLY B 1 260 ? 159.643 190.185 222.104 1.00 23.29 ? 244 GLY B C   1 
ATOM 5955 O O   . GLY B 1 260 ? 160.394 190.281 223.080 1.00 23.29 ? 244 GLY B O   1 
ATOM 5956 N N   . LYS B 1 261 ? 158.675 191.063 221.852 1.00 26.09 ? 245 LYS B N   1 
ATOM 5957 C CA  . LYS B 1 261 ? 158.433 192.218 222.705 1.00 26.09 ? 245 LYS B CA  1 
ATOM 5958 C C   . LYS B 1 261 ? 157.313 191.910 223.691 1.00 26.09 ? 245 LYS B C   1 
ATOM 5959 O O   . LYS B 1 261 ? 156.273 191.364 223.309 1.00 26.09 ? 245 LYS B O   1 
ATOM 5960 C CB  . LYS B 1 261 ? 158.072 193.444 221.866 1.00 26.09 ? 245 LYS B CB  1 
ATOM 5961 C CG  . LYS B 1 261 ? 159.169 193.895 220.918 1.00 26.09 ? 245 LYS B CG  1 
ATOM 5962 C CD  . LYS B 1 261 ? 158.816 195.220 220.262 1.00 26.09 ? 245 LYS B CD  1 
ATOM 5963 C CE  . LYS B 1 261 ? 159.829 195.596 219.194 1.00 26.09 ? 245 LYS B CE  1 
ATOM 5964 N NZ  . LYS B 1 261 ? 159.812 194.638 218.054 1.00 26.09 ? 245 LYS B NZ  1 
ATOM 5965 N N   . GLU B 1 262 ? 157.530 192.260 224.955 1.00 28.20 ? 246 GLU B N   1 
ATOM 5966 C CA  . GLU B 1 262 ? 156.503 192.080 225.967 1.00 28.20 ? 246 GLU B CA  1 
ATOM 5967 C C   . GLU B 1 262 ? 155.368 193.079 225.761 1.00 28.20 ? 246 GLU B C   1 
ATOM 5968 O O   . GLU B 1 262 ? 155.532 194.133 225.140 1.00 28.20 ? 246 GLU B O   1 
ATOM 5969 C CB  . GLU B 1 262 ? 157.092 192.239 227.369 1.00 28.20 ? 246 GLU B CB  1 
ATOM 5970 C CG  . GLU B 1 262 ? 157.458 190.928 228.043 1.00 28.20 ? 246 GLU B CG  1 
ATOM 5971 C CD  . GLU B 1 262 ? 157.650 191.074 229.539 1.00 28.20 ? 246 GLU B CD  1 
ATOM 5972 O OE1 . GLU B 1 262 ? 158.043 192.173 229.985 1.00 28.20 ? 246 GLU B OE1 1 
ATOM 5973 O OE2 . GLU B 1 262 ? 157.410 190.090 230.270 1.00 28.20 ? 246 GLU B OE2 1 
ATOM 5974 N N   . SER B 1 263 ? 154.194 192.729 226.288 1.00 26.11 ? 247 SER B N   1 
ATOM 5975 C CA  . SER B 1 263 ? 153.043 193.618 226.205 1.00 26.11 ? 247 SER B CA  1 
ATOM 5976 C C   . SER B 1 263 ? 153.114 194.765 227.204 1.00 26.11 ? 247 SER B C   1 
ATOM 5977 O O   . SER B 1 263 ? 152.389 195.753 227.044 1.00 26.11 ? 247 SER B O   1 
ATOM 5978 C CB  . SER B 1 263 ? 151.750 192.828 226.423 1.00 26.11 ? 247 SER B CB  1 
ATOM 5979 O OG  . SER B 1 263 ? 151.688 191.704 225.564 1.00 26.11 ? 247 SER B OG  1 
ATOM 5980 N N   . SER B 1 264 ? 153.966 194.657 228.226 1.00 26.66 ? 248 SER B N   1 
ATOM 5981 C CA  . SER B 1 264 ? 154.050 195.706 229.237 1.00 26.66 ? 248 SER B CA  1 
ATOM 5982 C C   . SER B 1 264 ? 154.741 196.950 228.690 1.00 26.66 ? 248 SER B C   1 
ATOM 5983 O O   . SER B 1 264 ? 154.282 198.076 228.914 1.00 26.66 ? 248 SER B O   1 
ATOM 5984 C CB  . SER B 1 264 ? 154.782 195.182 230.473 1.00 26.66 ? 248 SER B CB  1 
ATOM 5985 O OG  . SER B 1 264 ? 156.011 194.572 230.119 1.00 26.66 ? 248 SER B OG  1 
ATOM 5986 N N   . ARG B 1 265 ? 155.846 196.768 227.970 1.00 28.75 ? 249 ARG B N   1 
ATOM 5987 C CA  . ARG B 1 265 ? 156.642 197.877 227.466 1.00 28.75 ? 249 ARG B CA  1 
ATOM 5988 C C   . ARG B 1 265 ? 157.141 197.560 226.063 1.00 28.75 ? 249 ARG B C   1 
ATOM 5989 O O   . ARG B 1 265 ? 157.011 196.437 225.568 1.00 28.75 ? 249 ARG B O   1 
ATOM 5990 C CB  . ARG B 1 265 ? 157.826 198.181 228.394 1.00 28.75 ? 249 ARG B CB  1 
ATOM 5991 C CG  . ARG B 1 265 ? 157.563 199.299 229.389 1.00 28.75 ? 249 ARG B CG  1 
ATOM 5992 C CD  . ARG B 1 265 ? 157.396 200.636 228.686 1.00 28.75 ? 249 ARG B CD  1 
ATOM 5993 N NE  . ARG B 1 265 ? 157.303 201.741 229.632 1.00 28.75 ? 249 ARG B NE  1 
ATOM 5994 C CZ  . ARG B 1 265 ? 156.163 202.243 230.087 1.00 28.75 ? 249 ARG B CZ  1 
ATOM 5995 N NH1 . ARG B 1 265 ? 154.992 201.761 229.701 1.00 28.75 ? 249 ARG B NH1 1 
ATOM 5996 N NH2 . ARG B 1 265 ? 156.198 203.253 230.952 1.00 28.75 ? 249 ARG B NH2 1 
ATOM 5997 N N   . THR B 1 266 ? 157.723 198.572 225.423 1.00 26.85 ? 250 THR B N   1 
ATOM 5998 C CA  . THR B 1 266 ? 158.263 198.432 224.076 1.00 26.85 ? 250 THR B CA  1 
ATOM 5999 C C   . THR B 1 266 ? 159.685 197.888 224.059 1.00 26.85 ? 250 THR B C   1 
ATOM 6000 O O   . THR B 1 266 ? 160.253 197.722 222.974 1.00 26.85 ? 250 THR B O   1 
ATOM 6001 C CB  . THR B 1 266 ? 158.225 199.779 223.349 1.00 26.85 ? 250 THR B CB  1 
ATOM 6002 O OG1 . THR B 1 266 ? 158.926 200.762 224.122 1.00 26.85 ? 250 THR B OG1 1 
ATOM 6003 C CG2 . THR B 1 266 ? 156.788 200.233 223.144 1.00 26.85 ? 250 THR B CG2 1 
ATOM 6004 N N   . HIS B 1 267 ? 160.271 197.614 225.222 1.00 25.81 ? 251 HIS B N   1 
ATOM 6005 C CA  . HIS B 1 267 ? 161.632 197.087 225.306 1.00 25.81 ? 251 HIS B CA  1 
ATOM 6006 C C   . HIS B 1 267 ? 161.656 195.679 224.726 1.00 25.81 ? 251 HIS B C   1 
ATOM 6007 O O   . HIS B 1 267 ? 161.159 194.731 225.339 1.00 25.81 ? 251 HIS B O   1 
ATOM 6008 C CB  . HIS B 1 267 ? 162.115 197.096 226.752 1.00 25.81 ? 251 HIS B CB  1 
ATOM 6009 C CG  . HIS B 1 267 ? 163.592 197.289 226.895 1.00 25.81 ? 251 HIS B CG  1 
ATOM 6010 N ND1 . HIS B 1 267 ? 164.256 198.375 226.367 1.00 25.81 ? 251 HIS B ND1 1 
ATOM 6011 C CD2 . HIS B 1 267 ? 164.534 196.535 227.510 1.00 25.81 ? 251 HIS B CD2 1 
ATOM 6012 C CE1 . HIS B 1 267 ? 165.543 198.281 226.649 1.00 25.81 ? 251 HIS B CE1 1 
ATOM 6013 N NE2 . HIS B 1 267 ? 165.738 197.174 227.342 1.00 25.81 ? 251 HIS B NE2 1 
ATOM 6014 N N   . SER B 1 268 ? 162.234 195.538 223.536 1.00 25.53 ? 252 SER B N   1 
ATOM 6015 C CA  . SER B 1 268 ? 162.317 194.235 222.891 1.00 25.53 ? 252 SER B CA  1 
ATOM 6016 C C   . SER B 1 268 ? 163.291 193.334 223.640 1.00 25.53 ? 252 SER B C   1 
ATOM 6017 O O   . SER B 1 268 ? 164.375 193.768 224.040 1.00 25.53 ? 252 SER B O   1 
ATOM 6018 C CB  . SER B 1 268 ? 162.753 194.392 221.435 1.00 25.53 ? 252 SER B CB  1 
ATOM 6019 O OG  . SER B 1 268 ? 162.646 193.164 220.737 1.00 25.53 ? 252 SER B OG  1 
ATOM 6020 N N   . LEU B 1 269 ? 162.902 192.079 223.829 1.00 25.46 ? 253 LEU B N   1 
ATOM 6021 C CA  . LEU B 1 269 ? 163.725 191.102 224.524 1.00 25.46 ? 253 LEU B CA  1 
ATOM 6022 C C   . LEU B 1 269 ? 164.333 190.111 223.539 1.00 25.46 ? 253 LEU B C   1 
ATOM 6023 O O   . LEU B 1 269 ? 163.809 189.875 222.447 1.00 25.46 ? 253 LEU B O   1 
ATOM 6024 C CB  . LEU B 1 269 ? 162.907 190.357 225.583 1.00 25.46 ? 253 LEU B CB  1 
ATOM 6025 C CG  . LEU B 1 269 ? 162.620 191.121 226.878 1.00 25.46 ? 253 LEU B CG  1 
ATOM 6026 C CD1 . LEU B 1 269 ? 162.067 190.186 227.942 1.00 25.46 ? 253 LEU B CD1 1 
ATOM 6027 C CD2 . LEU B 1 269 ? 163.874 191.822 227.378 1.00 25.46 ? 253 LEU B CD2 1 
ATOM 6028 N N   . ALA B 1 270 ? 165.462 189.531 223.944 1.00 23.07 ? 254 ALA B N   1 
ATOM 6029 C CA  . ALA B 1 270 ? 166.201 188.565 223.136 1.00 23.07 ? 254 ALA B CA  1 
ATOM 6030 C C   . ALA B 1 270 ? 166.529 187.340 223.991 1.00 23.07 ? 254 ALA B C   1 
ATOM 6031 O O   . ALA B 1 270 ? 167.673 186.894 224.070 1.00 23.07 ? 254 ALA B O   1 
ATOM 6032 C CB  . ALA B 1 270 ? 167.466 189.185 222.549 1.00 23.07 ? 254 ALA B CB  1 
ATOM 6033 N N   . VAL B 1 271 ? 165.499 186.809 224.657 1.00 23.33 ? 255 VAL B N   1 
ATOM 6034 C CA  . VAL B 1 271 ? 165.682 185.677 225.559 1.00 23.33 ? 255 VAL B CA  1 
ATOM 6035 C C   . VAL B 1 271 ? 166.304 184.509 224.809 1.00 23.33 ? 255 VAL B C   1 
ATOM 6036 O O   . VAL B 1 271 ? 165.929 184.202 223.671 1.00 23.33 ? 255 VAL B O   1 
ATOM 6037 C CB  . VAL B 1 271 ? 164.343 185.288 226.204 1.00 23.33 ? 255 VAL B CB  1 
ATOM 6038 C CG1 . VAL B 1 271 ? 163.856 186.398 227.119 1.00 23.33 ? 255 VAL B CG1 1 
ATOM 6039 C CG2 . VAL B 1 271 ? 163.299 184.989 225.139 1.00 23.33 ? 255 VAL B CG2 1 
ATOM 6040 N N   . SER B 1 272 ? 167.279 183.863 225.442 1.00 22.26 ? 256 SER B N   1 
ATOM 6041 C CA  . SER B 1 272 ? 168.010 182.750 224.851 1.00 22.26 ? 256 SER B CA  1 
ATOM 6042 C C   . SER B 1 272 ? 167.752 181.486 225.658 1.00 22.26 ? 256 SER B C   1 
ATOM 6043 O O   . SER B 1 272 ? 167.826 181.505 226.892 1.00 22.26 ? 256 SER B O   1 
ATOM 6044 C CB  . SER B 1 272 ? 169.509 183.048 224.798 1.00 22.26 ? 256 SER B CB  1 
ATOM 6045 O OG  . SER B 1 272 ? 169.768 184.224 224.052 1.00 22.26 ? 256 SER B OG  1 
ATOM 6046 N N   . LEU B 1 273 ? 167.452 180.393 224.961 1.00 18.36 ? 257 LEU B N   1 
ATOM 6047 C CA  . LEU B 1 273 ? 167.200 179.106 225.588 1.00 18.36 ? 257 LEU B CA  1 
ATOM 6048 C C   . LEU B 1 273 ? 167.948 178.023 224.825 1.00 18.36 ? 257 LEU B C   1 
ATOM 6049 O O   . LEU B 1 273 ? 168.196 178.141 223.623 1.00 18.36 ? 257 LEU B O   1 
ATOM 6050 C CB  . LEU B 1 273 ? 165.698 178.761 225.639 1.00 18.36 ? 257 LEU B CB  1 
ATOM 6051 C CG  . LEU B 1 273 ? 164.840 178.646 224.370 1.00 18.36 ? 257 LEU B CG  1 
ATOM 6052 C CD1 . LEU B 1 273 ? 163.444 178.175 224.745 1.00 18.36 ? 257 LEU B CD1 1 
ATOM 6053 C CD2 . LEU B 1 273 ? 164.746 179.946 223.582 1.00 18.36 ? 257 LEU B CD2 1 
ATOM 6054 N N   . HIS B 1 274 ? 168.302 176.958 225.540 1.00 20.49 ? 258 HIS B N   1 
ATOM 6055 C CA  . HIS B 1 274 ? 169.023 175.832 224.965 1.00 20.49 ? 258 HIS B CA  1 
ATOM 6056 C C   . HIS B 1 274 ? 168.300 174.537 225.303 1.00 20.49 ? 258 HIS B C   1 
ATOM 6057 O O   . HIS B 1 274 ? 167.775 174.379 226.409 1.00 20.49 ? 258 HIS B O   1 
ATOM 6058 C CB  . HIS B 1 274 ? 170.475 175.781 225.468 1.00 20.49 ? 258 HIS B CB  1 
ATOM 6059 C CG  . HIS B 1 274 ? 170.600 175.646 226.954 1.00 20.49 ? 258 HIS B CG  1 
ATOM 6060 N ND1 . HIS B 1 274 ? 170.214 174.513 227.637 1.00 20.49 ? 258 HIS B ND1 1 
ATOM 6061 C CD2 . HIS B 1 274 ? 171.072 176.505 227.889 1.00 20.49 ? 258 HIS B CD2 1 
ATOM 6062 C CE1 . HIS B 1 274 ? 170.441 174.679 228.928 1.00 20.49 ? 258 HIS B CE1 1 
ATOM 6063 N NE2 . HIS B 1 274 ? 170.961 175.880 229.107 1.00 20.49 ? 258 HIS B NE2 1 
ATOM 6064 N N   . CYS B 1 275 ? 168.275 173.616 224.345 1.00 17.21 ? 259 CYS B N   1 
ATOM 6065 C CA  . CYS B 1 275 ? 167.614 172.336 224.540 1.00 17.21 ? 259 CYS B CA  1 
ATOM 6066 C C   . CYS B 1 275 ? 168.565 171.328 225.174 1.00 17.21 ? 259 CYS B C   1 
ATOM 6067 O O   . CYS B 1 275 ? 169.774 171.338 224.925 1.00 17.21 ? 259 CYS B O   1 
ATOM 6068 C CB  . CYS B 1 275 ? 167.091 171.795 223.210 1.00 17.21 ? 259 CYS B CB  1 
ATOM 6069 S SG  . CYS B 1 275 ? 165.674 172.697 222.547 1.00 17.21 ? 259 CYS B SG  1 
ATOM 6070 N N   . ALA B 1 276 ? 168.002 170.450 226.002 1.00 17.97 ? 260 ALA B N   1 
ATOM 6071 C CA  . ALA B 1 276 ? 168.772 169.414 226.673 1.00 17.97 ? 260 ALA B CA  1 
ATOM 6072 C C   . ALA B 1 276 ? 168.000 168.103 226.625 1.00 17.97 ? 260 ALA B C   1 
ATOM 6073 O O   . ALA B 1 276 ? 166.769 168.085 226.548 1.00 17.97 ? 260 ALA B O   1 
ATOM 6074 C CB  . ALA B 1 276 ? 169.088 169.793 228.126 1.00 17.97 ? 260 ALA B CB  1 
ATOM 6075 N N   . GLU B 1 277 ? 168.746 166.997 226.674 1.00 20.33 ? 261 GLU B N   1 
ATOM 6076 C CA  . GLU B 1 277 ? 168.122 165.679 226.642 1.00 20.33 ? 261 GLU B CA  1 
ATOM 6077 C C   . GLU B 1 277 ? 167.448 165.330 227.962 1.00 20.33 ? 261 GLU B C   1 
ATOM 6078 O O   . GLU B 1 277 ? 166.520 164.514 227.982 1.00 20.33 ? 261 GLU B O   1 
ATOM 6079 C CB  . GLU B 1 277 ? 169.159 164.611 226.286 1.00 20.33 ? 261 GLU B CB  1 
ATOM 6080 C CG  . GLU B 1 277 ? 170.273 164.457 227.308 1.00 20.33 ? 261 GLU B CG  1 
ATOM 6081 C CD  . GLU B 1 277 ? 170.978 163.119 227.206 1.00 20.33 ? 261 GLU B CD  1 
ATOM 6082 O OE1 . GLU B 1 277 ? 170.681 162.360 226.259 1.00 20.33 ? 261 GLU B OE1 1 
ATOM 6083 O OE2 . GLU B 1 277 ? 171.829 162.825 228.072 1.00 20.33 ? 261 GLU B OE2 1 
ATOM 6084 N N   . ASP B 1 278 ? 167.893 165.929 229.064 1.00 20.11 ? 262 ASP B N   1 
ATOM 6085 C CA  . ASP B 1 278 ? 167.316 165.675 230.377 1.00 20.11 ? 262 ASP B CA  1 
ATOM 6086 C C   . ASP B 1 278 ? 166.109 166.553 230.673 1.00 20.11 ? 262 ASP B C   1 
ATOM 6087 O O   . ASP B 1 278 ? 165.501 166.404 231.739 1.00 20.11 ? 262 ASP B O   1 
ATOM 6088 C CB  . ASP B 1 278 ? 168.376 165.875 231.465 1.00 20.11 ? 262 ASP B CB  1 
ATOM 6089 C CG  . ASP B 1 278 ? 169.538 164.910 231.331 1.00 20.11 ? 262 ASP B CG  1 
ATOM 6090 O OD1 . ASP B 1 278 ? 170.455 165.190 230.531 1.00 20.11 ? 262 ASP B OD1 1 
ATOM 6091 O OD2 . ASP B 1 278 ? 169.534 163.873 232.026 1.00 20.11 ? 262 ASP B OD2 1 
ATOM 6092 N N   . ASP B 1 279 ? 165.756 167.462 229.763 1.00 19.93 ? 263 ASP B N   1 
ATOM 6093 C CA  . ASP B 1 279 ? 164.622 168.373 229.916 1.00 19.93 ? 263 ASP B CA  1 
ATOM 6094 C C   . ASP B 1 279 ? 164.740 169.244 231.162 1.00 19.93 ? 263 ASP B C   1 
ATOM 6095 O O   . ASP B 1 279 ? 163.726 169.665 231.727 1.00 19.93 ? 263 ASP B O   1 
ATOM 6096 C CB  . ASP B 1 279 ? 163.291 167.610 229.927 1.00 19.93 ? 263 ASP B CB  1 
ATOM 6097 C CG  . ASP B 1 279 ? 163.112 166.734 228.703 1.00 19.93 ? 263 ASP B CG  1 
ATOM 6098 O OD1 . ASP B 1 279 ? 163.786 165.686 228.616 1.00 19.93 ? 263 ASP B OD1 1 
ATOM 6099 O OD2 . ASP B 1 279 ? 162.299 167.095 227.826 1.00 19.93 ? 263 ASP B OD2 1 
ATOM 6100 N N   . SER B 1 280 ? 165.967 169.523 231.604 1.00 21.23 ? 264 SER B N   1 
ATOM 6101 C CA  . SER B 1 280 ? 166.201 170.394 232.755 1.00 21.23 ? 264 SER B CA  1 
ATOM 6102 C C   . SER B 1 280 ? 166.547 171.787 232.237 1.00 21.23 ? 264 SER B C   1 
ATOM 6103 O O   . SER B 1 280 ? 167.708 172.195 232.164 1.00 21.23 ? 264 SER B O   1 
ATOM 6104 C CB  . SER B 1 280 ? 167.300 169.828 233.645 1.00 21.23 ? 264 SER B CB  1 
ATOM 6105 O OG  . SER B 1 280 ? 166.906 168.594 234.220 1.00 21.23 ? 264 SER B OG  1 
ATOM 6106 N N   . ILE B 1 281 ? 165.503 172.529 231.868 1.00 19.60 ? 265 ILE B N   1 
ATOM 6107 C CA  . ILE B 1 281 ? 165.691 173.869 231.327 1.00 19.60 ? 265 ILE B CA  1 
ATOM 6108 C C   . ILE B 1 281 ? 166.084 174.817 232.451 1.00 19.60 ? 265 ILE B C   1 
ATOM 6109 O O   . ILE B 1 281 ? 165.398 174.910 233.478 1.00 19.60 ? 265 ILE B O   1 
ATOM 6110 C CB  . ILE B 1 281 ? 164.419 174.347 230.612 1.00 19.60 ? 265 ILE B CB  1 
ATOM 6111 C CG1 . ILE B 1 281 ? 164.087 173.424 229.437 1.00 19.60 ? 265 ILE B CG1 1 
ATOM 6112 C CG2 . ILE B 1 281 ? 164.582 175.782 230.133 1.00 19.60 ? 265 ILE B CG2 1 
ATOM 6113 C CD1 . ILE B 1 281 ? 165.203 173.298 228.423 1.00 19.60 ? 265 ILE B CD1 1 
ATOM 6114 N N   . SER B 1 282 ? 167.192 175.527 232.261 1.00 20.53 ? 266 SER B N   1 
ATOM 6115 C CA  . SER B 1 282 ? 167.686 176.501 233.222 1.00 20.53 ? 266 SER B CA  1 
ATOM 6116 C C   . SER B 1 282 ? 167.584 177.895 232.621 1.00 20.53 ? 266 SER B C   1 
ATOM 6117 O O   . SER B 1 282 ? 167.804 178.080 231.420 1.00 20.53 ? 266 SER B O   1 
ATOM 6118 C CB  . SER B 1 282 ? 169.136 176.203 233.621 1.00 20.53 ? 266 SER B CB  1 
ATOM 6119 O OG  . SER B 1 282 ? 169.954 176.030 232.477 1.00 20.53 ? 266 SER B OG  1 
ATOM 6120 N N   . VAL B 1 283 ? 167.244 178.872 233.462 1.00 21.69 ? 267 VAL B N   1 
ATOM 6121 C CA  . VAL B 1 283 ? 167.087 180.241 232.983 1.00 21.69 ? 267 VAL B CA  1 
ATOM 6122 C C   . VAL B 1 283 ? 168.446 180.786 232.566 1.00 21.69 ? 267 VAL B C   1 
ATOM 6123 O O   . VAL B 1 283 ? 169.419 180.737 233.329 1.00 21.69 ? 267 VAL B O   1 
ATOM 6124 C CB  . VAL B 1 283 ? 166.415 181.114 234.051 1.00 21.69 ? 267 VAL B CB  1 
ATOM 6125 C CG1 . VAL B 1 283 ? 167.165 181.036 235.376 1.00 21.69 ? 267 VAL B CG1 1 
ATOM 6126 C CG2 . VAL B 1 283 ? 166.318 182.556 233.573 1.00 21.69 ? 267 VAL B CG2 1 
ATOM 6127 N N   . SER B 1 284 ? 168.526 181.284 231.336 1.00 18.15 ? 268 SER B N   1 
ATOM 6128 C CA  . SER B 1 284 ? 169.751 181.866 230.814 1.00 18.15 ? 268 SER B CA  1 
ATOM 6129 C C   . SER B 1 284 ? 169.692 183.386 230.957 1.00 18.15 ? 268 SER B C   1 
ATOM 6130 O O   . SER B 1 284 ? 168.705 183.948 231.440 1.00 18.15 ? 268 SER B O   1 
ATOM 6131 C CB  . SER B 1 284 ? 169.965 181.433 229.365 1.00 18.15 ? 268 SER B CB  1 
ATOM 6132 O OG  . SER B 1 284 ? 171.146 182.007 228.831 1.00 18.15 ? 268 SER B OG  1 
ATOM 6133 N N   . GLY B 1 285 ? 170.755 184.067 230.539 1.00 17.97 ? 269 GLY B N   1 
ATOM 6134 C CA  . GLY B 1 285 ? 170.768 185.517 230.607 1.00 17.97 ? 269 GLY B CA  1 
ATOM 6135 C C   . GLY B 1 285 ? 169.754 186.126 229.654 1.00 17.97 ? 269 GLY B C   1 
ATOM 6136 O O   . GLY B 1 285 ? 169.547 185.645 228.539 1.00 17.97 ? 269 GLY B O   1 
ATOM 6137 N N   . GLN B 1 286 ? 169.115 187.202 230.106 1.00 22.93 ? 270 GLN B N   1 
ATOM 6138 C CA  . GLN B 1 286 ? 168.104 187.898 229.317 1.00 22.93 ? 270 GLN B CA  1 
ATOM 6139 C C   . GLN B 1 286 ? 168.755 189.100 228.643 1.00 22.93 ? 270 GLN B C   1 
ATOM 6140 O O   . GLN B 1 286 ? 169.057 190.102 229.300 1.00 22.93 ? 270 GLN B O   1 
ATOM 6141 C CB  . GLN B 1 286 ? 166.933 188.326 230.196 1.00 22.93 ? 270 GLN B CB  1 
ATOM 6142 C CG  . GLN B 1 286 ? 166.187 187.173 230.847 1.00 22.93 ? 270 GLN B CG  1 
ATOM 6143 C CD  . GLN B 1 286 ? 166.736 186.823 232.217 1.00 22.93 ? 270 GLN B CD  1 
ATOM 6144 O OE1 . GLN B 1 286 ? 167.926 186.544 232.368 1.00 22.93 ? 270 GLN B OE1 1 
ATOM 6145 N NE2 . GLN B 1 286 ? 165.871 186.838 233.223 1.00 22.93 ? 270 GLN B NE2 1 
ATOM 6146 N N   . ASN B 1 287 ? 168.969 189.002 227.336 1.00 25.56 ? 271 ASN B N   1 
ATOM 6147 C CA  . ASN B 1 287 ? 169.553 190.091 226.569 1.00 25.56 ? 271 ASN B CA  1 
ATOM 6148 C C   . ASN B 1 287 ? 168.533 191.205 226.373 1.00 25.56 ? 271 ASN B C   1 
ATOM 6149 O O   . ASN B 1 287 ? 167.331 190.959 226.243 1.00 25.56 ? 271 ASN B O   1 
ATOM 6150 C CB  . ASN B 1 287 ? 170.054 189.593 225.213 1.00 25.56 ? 271 ASN B CB  1 
ATOM 6151 C CG  . ASN B 1 287 ? 171.120 188.523 225.343 1.00 25.56 ? 271 ASN B CG  1 
ATOM 6152 O OD1 . ASN B 1 287 ? 171.257 187.892 226.391 1.00 25.56 ? 271 ASN B OD1 1 
ATOM 6153 N ND2 . ASN B 1 287 ? 171.883 188.315 224.277 1.00 25.56 ? 271 ASN B ND2 1 
ATOM 6154 N N   . SER B 1 288 ? 169.027 192.441 226.355 1.00 28.65 ? 272 SER B N   1 
ATOM 6155 C CA  . SER B 1 288 ? 168.182 193.617 226.223 1.00 28.65 ? 272 SER B CA  1 
ATOM 6156 C C   . SER B 1 288 ? 168.661 194.466 225.055 1.00 28.65 ? 272 SER B C   1 
ATOM 6157 O O   . SER B 1 288 ? 169.850 194.490 224.728 1.00 28.65 ? 272 SER B O   1 
ATOM 6158 C CB  . SER B 1 288 ? 168.176 194.454 227.510 1.00 28.65 ? 272 SER B CB  1 
ATOM 6159 O OG  . SER B 1 288 ? 169.053 195.562 227.401 1.00 28.65 ? 272 SER B OG  1 
ATOM 6160 N N   . LEU B 1 289 ? 167.716 195.162 224.429 1.00 27.53 ? 273 LEU B N   1 
ATOM 6161 C CA  . LEU B 1 289 ? 167.990 196.003 223.275 1.00 27.53 ? 273 LEU B CA  1 
ATOM 6162 C C   . LEU B 1 289 ? 166.974 197.138 223.227 1.00 27.53 ? 273 LEU B C   1 
ATOM 6163 O O   . LEU B 1 289 ? 165.888 197.043 223.805 1.00 27.53 ? 273 LEU B O   1 
ATOM 6164 C CB  . LEU B 1 289 ? 167.984 195.160 221.982 1.00 27.53 ? 273 LEU B CB  1 
ATOM 6165 C CG  . LEU B 1 289 ? 166.689 194.800 221.249 1.00 27.53 ? 273 LEU B CG  1 
ATOM 6166 C CD1 . LEU B 1 289 ? 166.229 195.919 220.343 1.00 27.53 ? 273 LEU B CD1 1 
ATOM 6167 C CD2 . LEU B 1 289 ? 166.864 193.510 220.462 1.00 27.53 ? 273 LEU B CD2 1 
ATOM 6168 N N   . CYS B 1 290 ? 167.337 198.215 222.528 1.00 27.50 ? 274 CYS B N   1 
ATOM 6169 C CA  . CYS B 1 290 ? 166.587 199.466 222.577 1.00 27.50 ? 274 CYS B CA  1 
ATOM 6170 C C   . CYS B 1 290 ? 165.686 199.692 221.367 1.00 27.50 ? 274 CYS B C   1 
ATOM 6171 O O   . CYS B 1 290 ? 164.475 199.876 221.525 1.00 27.50 ? 274 CYS B O   1 
ATOM 6172 C CB  . CYS B 1 290 ? 167.558 200.645 222.722 1.00 27.50 ? 274 CYS B CB  1 
ATOM 6173 S SG  . CYS B 1 290 ? 166.763 202.267 222.763 1.00 27.50 ? 274 CYS B SG  1 
ATOM 6174 N N   . HIS B 1 291 ? 166.247 199.686 220.161 1.00 37.08 ? 275 HIS B N   1 
ATOM 6175 C CA  . HIS B 1 291 ? 165.531 200.116 218.969 1.00 37.08 ? 275 HIS B CA  1 
ATOM 6176 C C   . HIS B 1 291 ? 164.639 198.991 218.442 1.00 37.08 ? 275 HIS B C   1 
ATOM 6177 O O   . HIS B 1 291 ? 164.371 198.004 219.129 1.00 37.08 ? 275 HIS B O   1 
ATOM 6178 C CB  . HIS B 1 291 ? 166.520 200.600 217.912 1.00 37.08 ? 275 HIS B CB  1 
ATOM 6179 C CG  . HIS B 1 291 ? 167.424 201.695 218.387 1.00 37.08 ? 275 HIS B CG  1 
ATOM 6180 N ND1 . HIS B 1 291 ? 167.002 203.000 218.523 1.00 37.08 ? 275 HIS B ND1 1 
ATOM 6181 C CD2 . HIS B 1 291 ? 168.725 201.680 218.759 1.00 37.08 ? 275 HIS B CD2 1 
ATOM 6182 C CE1 . HIS B 1 291 ? 168.006 203.742 218.957 1.00 37.08 ? 275 HIS B CE1 1 
ATOM 6183 N NE2 . HIS B 1 291 ? 169.063 202.965 219.108 1.00 37.08 ? 275 HIS B NE2 1 
ATOM 6184 N N   . GLN B 1 292 ? 164.138 199.150 217.221 1.00 27.66 ? 276 GLN B N   1 
ATOM 6185 C CA  . GLN B 1 292 ? 163.310 198.134 216.592 1.00 27.66 ? 276 GLN B CA  1 
ATOM 6186 C C   . GLN B 1 292 ? 164.165 197.204 215.733 1.00 27.66 ? 276 GLN B C   1 
ATOM 6187 O O   . GLN B 1 292 ? 165.306 197.510 215.379 1.00 27.66 ? 276 GLN B O   1 
ATOM 6188 C CB  . GLN B 1 292 ? 162.209 198.785 215.755 1.00 27.66 ? 276 GLN B CB  1 
ATOM 6189 C CG  . GLN B 1 292 ? 162.657 199.239 214.376 1.00 27.66 ? 276 GLN B CG  1 
ATOM 6190 C CD  . GLN B 1 292 ? 161.565 199.973 213.623 1.00 27.66 ? 276 GLN B CD  1 
ATOM 6191 O OE1 . GLN B 1 292 ? 160.532 200.325 214.193 1.00 27.66 ? 276 GLN B OE1 1 
ATOM 6192 N NE2 . GLN B 1 292 ? 161.787 200.206 212.335 1.00 27.66 ? 276 GLN B NE2 1 
ATOM 6193 N N   . ILE B 1 293 ? 163.596 196.047 215.401 1.00 23.89 ? 277 ILE B N   1 
ATOM 6194 C CA  . ILE B 1 293 ? 164.282 195.004 214.643 1.00 23.89 ? 277 ILE B CA  1 
ATOM 6195 C C   . ILE B 1 293 ? 163.654 194.912 213.261 1.00 23.89 ? 277 ILE B C   1 
ATOM 6196 O O   . ILE B 1 293 ? 162.424 194.884 213.132 1.00 23.89 ? 277 ILE B O   1 
ATOM 6197 C CB  . ILE B 1 293 ? 164.219 193.634 215.350 1.00 23.89 ? 277 ILE B CB  1 
ATOM 6198 C CG1 . ILE B 1 293 ? 164.694 193.702 216.807 1.00 23.89 ? 277 ILE B CG1 1 
ATOM 6199 C CG2 . ILE B 1 293 ? 165.035 192.603 214.582 1.00 23.89 ? 277 ILE B CG2 1 
ATOM 6200 C CD1 . ILE B 1 293 ? 165.820 194.677 217.072 1.00 23.89 ? 277 ILE B CD1 1 
ATOM 6201 N N   . THR B 1 294 ? 164.498 194.863 212.234 1.00 25.61 ? 278 THR B N   1 
ATOM 6202 C CA  . THR B 1 294 ? 164.065 194.611 210.865 1.00 25.61 ? 278 THR B CA  1 
ATOM 6203 C C   . THR B 1 294 ? 164.327 193.183 210.416 1.00 25.61 ? 278 THR B C   1 
ATOM 6204 O O   . THR B 1 294 ? 163.437 192.546 209.849 1.00 25.61 ? 278 THR B O   1 
ATOM 6205 C CB  . THR B 1 294 ? 164.760 195.579 209.900 1.00 25.61 ? 278 THR B CB  1 
ATOM 6206 O OG1 . THR B 1 294 ? 164.408 196.926 210.237 1.00 25.61 ? 278 THR B OG1 1 
ATOM 6207 C CG2 . THR B 1 294 ? 164.343 195.299 208.466 1.00 25.61 ? 278 THR B CG2 1 
ATOM 6208 N N   . ALA B 1 295 ? 165.525 192.660 210.668 1.00 19.99 ? 279 ALA B N   1 
ATOM 6209 C CA  . ALA B 1 295 ? 165.855 191.282 210.340 1.00 19.99 ? 279 ALA B CA  1 
ATOM 6210 C C   . ALA B 1 295 ? 166.959 190.807 211.273 1.00 19.99 ? 279 ALA B C   1 
ATOM 6211 O O   . ALA B 1 295 ? 167.671 191.608 211.883 1.00 19.99 ? 279 ALA B O   1 
ATOM 6212 C CB  . ALA B 1 295 ? 166.282 191.134 208.875 1.00 19.99 ? 279 ALA B CB  1 
ATOM 6213 N N   . ALA B 1 296 ? 167.092 189.487 211.381 1.00 16.38 ? 280 ALA B N   1 
ATOM 6214 C CA  . ALA B 1 296 ? 168.085 188.894 212.263 1.00 16.38 ? 280 ALA B CA  1 
ATOM 6215 C C   . ALA B 1 296 ? 168.639 187.632 211.620 1.00 16.38 ? 280 ALA B C   1 
ATOM 6216 O O   . ALA B 1 296 ? 167.982 186.991 210.795 1.00 16.38 ? 280 ALA B O   1 
ATOM 6217 C CB  . ALA B 1 296 ? 167.497 188.578 213.643 1.00 16.38 ? 280 ALA B CB  1 
ATOM 6218 N N   . CYS B 1 297 ? 169.861 187.280 212.012 1.00 15.77 ? 281 CYS B N   1 
ATOM 6219 C CA  . CYS B 1 297 ? 170.535 186.101 211.490 1.00 15.77 ? 281 CYS B CA  1 
ATOM 6220 C C   . CYS B 1 297 ? 171.222 185.364 212.628 1.00 15.77 ? 281 CYS B C   1 
ATOM 6221 O O   . CYS B 1 297 ? 171.609 185.964 213.634 1.00 15.77 ? 281 CYS B O   1 
ATOM 6222 C CB  . CYS B 1 297 ? 171.559 186.469 210.410 1.00 15.77 ? 281 CYS B CB  1 
ATOM 6223 S SG  . CYS B 1 297 ? 172.616 185.102 209.897 1.00 15.77 ? 281 CYS B SG  1 
ATOM 6224 N N   . LYS B 1 298 ? 171.375 184.055 212.456 1.00 19.25 ? 282 LYS B N   1 
ATOM 6225 C CA  . LYS B 1 298 ? 172.001 183.186 213.450 1.00 19.25 ? 282 LYS B CA  1 
ATOM 6226 C C   . LYS B 1 298 ? 173.246 182.569 212.820 1.00 19.25 ? 282 LYS B C   1 
ATOM 6227 O O   . LYS B 1 298 ? 173.148 181.668 211.982 1.00 19.25 ? 282 LYS B O   1 
ATOM 6228 C CB  . LYS B 1 298 ? 171.026 182.113 213.925 1.00 19.25 ? 282 LYS B CB  1 
ATOM 6229 C CG  . LYS B 1 298 ? 171.654 181.031 214.789 1.00 19.25 ? 282 LYS B CG  1 
ATOM 6230 C CD  . LYS B 1 298 ? 172.058 181.574 216.148 1.00 19.25 ? 282 LYS B CD  1 
ATOM 6231 C CE  . LYS B 1 298 ? 172.705 180.495 217.000 1.00 19.25 ? 282 LYS B CE  1 
ATOM 6232 N NZ  . LYS B 1 298 ? 171.860 179.273 217.085 1.00 19.25 ? 282 LYS B NZ  1 
ATOM 6233 N N   . HIS B 1 299 ? 174.416 183.060 213.223 1.00 20.25 ? 283 HIS B N   1 
ATOM 6234 C CA  . HIS B 1 299 ? 175.695 182.555 212.741 1.00 20.25 ? 283 HIS B CA  1 
ATOM 6235 C C   . HIS B 1 299 ? 176.507 182.067 213.931 1.00 20.25 ? 283 HIS B C   1 
ATOM 6236 O O   . HIS B 1 299 ? 176.707 182.813 214.896 1.00 20.25 ? 283 HIS B O   1 
ATOM 6237 C CB  . HIS B 1 299 ? 176.460 183.635 211.973 1.00 20.25 ? 283 HIS B CB  1 
ATOM 6238 C CG  . HIS B 1 299 ? 177.726 183.146 211.343 1.00 20.25 ? 283 HIS B CG  1 
ATOM 6239 N ND1 . HIS B 1 299 ? 178.717 183.999 210.906 1.00 20.25 ? 283 HIS B ND1 1 
ATOM 6240 C CD2 . HIS B 1 299 ? 178.165 181.893 211.078 1.00 20.25 ? 283 HIS B CD2 1 
ATOM 6241 C CE1 . HIS B 1 299 ? 179.711 183.293 210.398 1.00 20.25 ? 283 HIS B CE1 1 
ATOM 6242 N NE2 . HIS B 1 299 ? 179.401 182.012 210.491 1.00 20.25 ? 283 HIS B NE2 1 
ATOM 6243 N N   . GLY B 1 300 ? 176.977 180.823 213.858 1.00 19.86 ? 284 GLY B N   1 
ATOM 6244 C CA  . GLY B 1 300 ? 177.786 180.247 214.914 1.00 19.86 ? 284 GLY B CA  1 
ATOM 6245 C C   . GLY B 1 300 ? 177.125 180.291 216.276 1.00 19.86 ? 284 GLY B C   1 
ATOM 6246 O O   . GLY B 1 300 ? 176.133 179.598 216.518 1.00 19.86 ? 284 GLY B O   1 
ATOM 6247 N N   . GLY B 1 301 ? 177.672 181.105 217.174 1.00 22.08 ? 285 GLY B N   1 
ATOM 6248 C CA  . GLY B 1 301 ? 177.106 181.263 218.498 1.00 22.08 ? 285 GLY B CA  1 
ATOM 6249 C C   . GLY B 1 301 ? 176.835 182.710 218.853 1.00 22.08 ? 285 GLY B C   1 
ATOM 6250 O O   . GLY B 1 301 ? 176.800 183.071 220.033 1.00 22.08 ? 285 GLY B O   1 
ATOM 6251 N N   . ASP B 1 302 ? 176.643 183.550 217.837 1.00 21.56 ? 286 ASP B N   1 
ATOM 6252 C CA  . ASP B 1 302 ? 176.367 184.964 218.033 1.00 21.56 ? 286 ASP B CA  1 
ATOM 6253 C C   . ASP B 1 302 ? 175.197 185.383 217.155 1.00 21.56 ? 286 ASP B C   1 
ATOM 6254 O O   . ASP B 1 302 ? 174.910 184.756 216.132 1.00 21.56 ? 286 ASP B O   1 
ATOM 6255 C CB  . ASP B 1 302 ? 177.603 185.831 217.730 1.00 21.56 ? 286 ASP B CB  1 
ATOM 6256 C CG  . ASP B 1 302 ? 178.259 185.481 216.404 1.00 21.56 ? 286 ASP B CG  1 
ATOM 6257 O OD1 . ASP B 1 302 ? 177.550 185.405 215.379 1.00 21.56 ? 286 ASP B OD1 1 
ATOM 6258 O OD2 . ASP B 1 302 ? 179.492 185.282 216.389 1.00 21.56 ? 286 ASP B OD2 1 
ATOM 6259 N N   . LEU B 1 303 ? 174.522 186.451 217.569 1.00 21.06 ? 287 LEU B N   1 
ATOM 6260 C CA  . LEU B 1 303 ? 173.333 186.949 216.891 1.00 21.06 ? 287 LEU B CA  1 
ATOM 6261 C C   . LEU B 1 303 ? 173.648 188.276 216.213 1.00 21.06 ? 287 LEU B C   1 
ATOM 6262 O O   . LEU B 1 303 ? 174.174 189.194 216.850 1.00 21.06 ? 287 LEU B O   1 
ATOM 6263 C CB  . LEU B 1 303 ? 172.178 187.120 217.880 1.00 21.06 ? 287 LEU B CB  1 
ATOM 6264 C CG  . LEU B 1 303 ? 170.825 187.557 217.317 1.00 21.06 ? 287 LEU B CG  1 
ATOM 6265 C CD1 . LEU B 1 303 ? 170.188 186.434 216.517 1.00 21.06 ? 287 LEU B CD1 1 
ATOM 6266 C CD2 . LEU B 1 303 ? 169.904 188.007 218.439 1.00 21.06 ? 287 LEU B CD2 1 
ATOM 6267 N N   . TYR B 1 304 ? 173.327 188.370 214.925 1.00 20.73 ? 288 TYR B N   1 
ATOM 6268 C CA  . TYR B 1 304 ? 173.492 189.595 214.146 1.00 20.73 ? 288 TYR B CA  1 
ATOM 6269 C C   . TYR B 1 304 ? 172.108 190.210 213.961 1.00 20.73 ? 288 TYR B C   1 
ATOM 6270 O O   . TYR B 1 304 ? 171.230 189.607 213.338 1.00 20.73 ? 288 TYR B O   1 
ATOM 6271 C CB  . TYR B 1 304 ? 174.163 189.309 212.805 1.00 20.73 ? 288 TYR B CB  1 
ATOM 6272 C CG  . TYR B 1 304 ? 175.589 188.821 212.921 1.00 20.73 ? 288 TYR B CG  1 
ATOM 6273 C CD1 . TYR B 1 304 ? 176.596 189.662 213.372 1.00 20.73 ? 288 TYR B CD1 1 
ATOM 6274 C CD2 . TYR B 1 304 ? 175.927 187.518 212.582 1.00 20.73 ? 288 TYR B CD2 1 
ATOM 6275 C CE1 . TYR B 1 304 ? 177.901 189.219 213.479 1.00 20.73 ? 288 TYR B CE1 1 
ATOM 6276 C CE2 . TYR B 1 304 ? 177.229 187.067 212.688 1.00 20.73 ? 288 TYR B CE2 1 
ATOM 6277 C CZ  . TYR B 1 304 ? 178.211 187.921 213.138 1.00 20.73 ? 288 TYR B CZ  1 
ATOM 6278 O OH  . TYR B 1 304 ? 179.509 187.477 213.244 1.00 20.73 ? 288 TYR B OH  1 
ATOM 6279 N N   . VAL B 1 305 ? 171.918 191.409 214.504 1.00 18.27 ? 289 VAL B N   1 
ATOM 6280 C CA  . VAL B 1 305 ? 170.630 192.091 214.480 1.00 18.27 ? 289 VAL B CA  1 
ATOM 6281 C C   . VAL B 1 305 ? 170.747 193.338 213.617 1.00 18.27 ? 289 VAL B C   1 
ATOM 6282 O O   . VAL B 1 305 ? 171.650 194.160 213.815 1.00 18.27 ? 289 VAL B O   1 
ATOM 6283 C CB  . VAL B 1 305 ? 170.167 192.450 215.902 1.00 18.27 ? 289 VAL B CB  1 
ATOM 6284 C CG1 . VAL B 1 305 ? 169.040 193.467 215.853 1.00 18.27 ? 289 VAL B CG1 1 
ATOM 6285 C CG2 . VAL B 1 305 ? 169.728 191.201 216.645 1.00 18.27 ? 289 VAL B CG2 1 
ATOM 6286 N N   . VAL B 1 306 ? 169.832 193.481 212.661 1.00 22.04 ? 290 VAL B N   1 
ATOM 6287 C CA  . VAL B 1 306 ? 169.733 194.669 211.823 1.00 22.04 ? 290 VAL B CA  1 
ATOM 6288 C C   . VAL B 1 306 ? 168.387 195.322 212.102 1.00 22.04 ? 290 VAL B C   1 
ATOM 6289 O O   . VAL B 1 306 ? 167.434 194.644 212.504 1.00 22.04 ? 290 VAL B O   1 
ATOM 6290 C CB  . VAL B 1 306 ? 169.888 194.334 210.325 1.00 22.04 ? 290 VAL B CB  1 
ATOM 6291 C CG1 . VAL B 1 306 ? 168.559 193.913 209.717 1.00 22.04 ? 290 VAL B CG1 1 
ATOM 6292 C CG2 . VAL B 1 306 ? 170.462 195.520 209.570 1.00 22.04 ? 290 VAL B CG2 1 
ATOM 6293 N N   . GLY B 1 307 ? 168.316 196.637 211.923 1.00 22.25 ? 291 GLY B N   1 
ATOM 6294 C CA  . GLY B 1 307 ? 167.066 197.338 212.172 1.00 22.25 ? 291 GLY B CA  1 
ATOM 6295 C C   . GLY B 1 307 ? 167.301 198.699 212.788 1.00 22.25 ? 291 GLY B C   1 
ATOM 6296 O O   . GLY B 1 307 ? 168.299 199.368 212.497 1.00 22.25 ? 291 GLY B O   1 
ATOM 6297 N N   . GLY B 1 308 ? 166.370 199.098 213.644 1.00 24.31 ? 292 GLY B N   1 
ATOM 6298 C CA  . GLY B 1 308 ? 166.423 200.393 214.289 1.00 24.31 ? 292 GLY B CA  1 
ATOM 6299 C C   . GLY B 1 308 ? 165.778 201.477 213.450 1.00 24.31 ? 292 GLY B C   1 
ATOM 6300 O O   . GLY B 1 308 ? 165.056 201.225 212.481 1.00 24.31 ? 292 GLY B O   1 
ATOM 6301 N N   . SER B 1 309 ? 166.050 202.721 213.853 1.00 24.03 ? 293 SER B N   1 
ATOM 6302 C CA  . SER B 1 309 ? 165.526 203.866 213.115 1.00 24.03 ? 293 SER B CA  1 
ATOM 6303 C C   . SER B 1 309 ? 166.081 203.905 211.696 1.00 24.03 ? 293 SER B C   1 
ATOM 6304 O O   . SER B 1 309 ? 165.351 204.201 210.743 1.00 24.03 ? 293 SER B O   1 
ATOM 6305 C CB  . SER B 1 309 ? 165.852 205.162 213.857 1.00 24.03 ? 293 SER B CB  1 
ATOM 6306 O OG  . SER B 1 309 ? 165.399 206.292 213.132 1.00 24.03 ? 293 SER B OG  1 
ATOM 6307 N N   . ILE B 1 310 ? 167.364 203.610 211.537 1.00 25.47 ? 294 ILE B N   1 
ATOM 6308 C CA  . ILE B 1 310 ? 168.018 203.574 210.231 1.00 25.47 ? 294 ILE B CA  1 
ATOM 6309 C C   . ILE B 1 310 ? 168.347 202.120 209.914 1.00 25.47 ? 294 ILE B C   1 
ATOM 6310 O O   . ILE B 1 310 ? 169.033 201.465 210.714 1.00 25.47 ? 294 ILE B O   1 
ATOM 6311 C CB  . ILE B 1 310 ? 169.282 204.445 210.208 1.00 25.47 ? 294 ILE B CB  1 
ATOM 6312 C CG1 . ILE B 1 310 ? 169.127 205.628 211.164 1.00 25.47 ? 294 ILE B CG1 1 
ATOM 6313 C CG2 . ILE B 1 310 ? 169.545 204.952 208.800 1.00 25.47 ? 294 ILE B CG2 1 
ATOM 6314 C CD1 . ILE B 1 310 ? 170.323 206.551 211.193 1.00 25.47 ? 294 ILE B CD1 1 
ATOM 6315 N N   . PRO B 1 311 ? 167.886 201.577 208.783 1.00 27.21 ? 295 PRO B N   1 
ATOM 6316 C CA  . PRO B 1 311 ? 168.079 200.143 208.507 1.00 27.21 ? 295 PRO B CA  1 
ATOM 6317 C C   . PRO B 1 311 ? 169.532 199.700 208.410 1.00 27.21 ? 295 PRO B C   1 
ATOM 6318 O O   . PRO B 1 311 ? 169.795 198.498 208.540 1.00 27.21 ? 295 PRO B O   1 
ATOM 6319 C CB  . PRO B 1 311 ? 167.351 199.972 207.157 1.00 27.21 ? 295 PRO B CB  1 
ATOM 6320 C CG  . PRO B 1 311 ? 167.392 201.413 206.622 1.00 27.21 ? 295 PRO B CG  1 
ATOM 6321 C CD  . PRO B 1 311 ? 166.884 202.075 207.838 1.00 27.21 ? 295 PRO B CD  1 
ATOM 6322 N N   . ARG B 1 312 ? 170.477 200.611 208.185 1.00 26.85 ? 296 ARG B N   1 
ATOM 6323 C CA  . ARG B 1 312 ? 171.873 200.241 207.994 1.00 26.85 ? 296 ARG B CA  1 
ATOM 6324 C C   . ARG B 1 312 ? 172.582 199.885 209.297 1.00 26.85 ? 296 ARG B C   1 
ATOM 6325 O O   . ARG B 1 312 ? 173.753 199.492 209.262 1.00 26.85 ? 296 ARG B O   1 
ATOM 6326 C CB  . ARG B 1 312 ? 172.634 201.371 207.295 1.00 26.85 ? 296 ARG B CB  1 
ATOM 6327 C CG  . ARG B 1 312 ? 171.950 202.726 207.347 1.00 26.85 ? 296 ARG B CG  1 
ATOM 6328 C CD  . ARG B 1 312 ? 172.569 203.694 206.349 1.00 26.85 ? 296 ARG B CD  1 
ATOM 6329 N NE  . ARG B 1 312 ? 171.641 204.745 205.950 1.00 26.85 ? 296 ARG B NE  1 
ATOM 6330 C CZ  . ARG B 1 312 ? 171.850 205.587 204.948 1.00 26.85 ? 296 ARG B CZ  1 
ATOM 6331 N NH1 . ARG B 1 312 ? 172.950 205.531 204.216 1.00 26.85 ? 296 ARG B NH1 1 
ATOM 6332 N NH2 . ARG B 1 312 ? 170.931 206.509 204.673 1.00 26.85 ? 296 ARG B NH2 1 
ATOM 6333 N N   . ARG B 1 313 ? 171.908 200.011 210.437 1.00 27.80 ? 297 ARG B N   1 
ATOM 6334 C CA  . ARG B 1 313 ? 172.521 199.760 211.734 1.00 27.80 ? 297 ARG B CA  1 
ATOM 6335 C C   . ARG B 1 313 ? 172.735 198.264 211.932 1.00 27.80 ? 297 ARG B C   1 
ATOM 6336 O O   . ARG B 1 313 ? 171.794 197.474 211.803 1.00 27.80 ? 297 ARG B O   1 
ATOM 6337 C CB  . ARG B 1 313 ? 171.647 200.322 212.855 1.00 27.80 ? 297 ARG B CB  1 
ATOM 6338 C CG  . ARG B 1 313 ? 172.219 200.131 214.247 1.00 27.80 ? 297 ARG B CG  1 
ATOM 6339 C CD  . ARG B 1 313 ? 173.029 201.343 214.678 1.00 27.80 ? 297 ARG B CD  1 
ATOM 6340 N NE  . ARG B 1 313 ? 172.176 202.477 215.013 1.00 27.80 ? 297 ARG B NE  1 
ATOM 6341 C CZ  . ARG B 1 313 ? 171.972 203.522 214.223 1.00 27.80 ? 297 ARG B CZ  1 
ATOM 6342 N NH1 . ARG B 1 313 ? 172.553 203.616 213.038 1.00 27.80 ? 297 ARG B NH1 1 
ATOM 6343 N NH2 . ARG B 1 313 ? 171.166 204.497 214.632 1.00 27.80 ? 297 ARG B NH2 1 
ATOM 6344 N N   . MET B 1 314 ? 173.970 197.882 212.251 1.00 21.18 ? 298 MET B N   1 
ATOM 6345 C CA  . MET B 1 314 ? 174.351 196.487 212.473 1.00 21.18 ? 298 MET B CA  1 
ATOM 6346 C C   . MET B 1 314 ? 174.755 196.327 213.936 1.00 21.18 ? 298 MET B C   1 
ATOM 6347 O O   . MET B 1 314 ? 175.930 196.466 214.286 1.00 21.18 ? 298 MET B O   1 
ATOM 6348 C CB  . MET B 1 314 ? 175.481 196.070 211.532 1.00 21.18 ? 298 MET B CB  1 
ATOM 6349 C CG  . MET B 1 314 ? 175.340 194.664 210.973 1.00 21.18 ? 298 MET B CG  1 
ATOM 6350 S SD  . MET B 1 314 ? 173.653 194.273 210.478 1.00 21.18 ? 298 MET B SD  1 
ATOM 6351 C CE  . MET B 1 314 ? 173.819 192.544 210.041 1.00 21.18 ? 298 MET B CE  1 
ATOM 6352 N N   . TRP B 1 315 ? 173.778 196.027 214.789 1.00 26.93 ? 299 TRP B N   1 
ATOM 6353 C CA  . TRP B 1 315 ? 174.023 195.823 216.217 1.00 26.93 ? 299 TRP B CA  1 
ATOM 6354 C C   . TRP B 1 315 ? 174.246 194.336 216.459 1.00 26.93 ? 299 TRP B C   1 
ATOM 6355 O O   . TRP B 1 315 ? 173.307 193.570 216.680 1.00 26.93 ? 299 TRP B O   1 
ATOM 6356 C CB  . TRP B 1 315 ? 172.865 196.361 217.047 1.00 26.93 ? 299 TRP B CB  1 
ATOM 6357 C CG  . TRP B 1 315 ? 173.075 197.762 217.527 1.00 26.93 ? 299 TRP B CG  1 
ATOM 6358 C CD1 . TRP B 1 315 ? 173.864 198.715 216.954 1.00 26.93 ? 299 TRP B CD1 1 
ATOM 6359 C CD2 . TRP B 1 315 ? 172.489 198.369 218.685 1.00 26.93 ? 299 TRP B CD2 1 
ATOM 6360 N NE1 . TRP B 1 315 ? 173.806 199.879 217.682 1.00 26.93 ? 299 TRP B NE1 1 
ATOM 6361 C CE2 . TRP B 1 315 ? 172.968 199.692 218.749 1.00 26.93 ? 299 TRP B CE2 1 
ATOM 6362 C CE3 . TRP B 1 315 ? 171.605 197.923 219.672 1.00 26.93 ? 299 TRP B CE3 1 
ATOM 6363 C CZ2 . TRP B 1 315 ? 172.593 200.573 219.762 1.00 26.93 ? 299 TRP B CZ2 1 
ATOM 6364 C CZ3 . TRP B 1 315 ? 171.234 198.799 220.676 1.00 26.93 ? 299 TRP B CZ3 1 
ATOM 6365 C CH2 . TRP B 1 315 ? 171.727 200.109 220.713 1.00 26.93 ? 299 TRP B CH2 1 
ATOM 6366 N N   . LYS B 1 316 ? 175.510 193.924 216.420 1.00 20.21 ? 300 LYS B N   1 
ATOM 6367 C CA  . LYS B 1 316 ? 175.865 192.535 216.676 1.00 20.21 ? 300 LYS B CA  1 
ATOM 6368 C C   . LYS B 1 316 ? 175.775 192.238 218.167 1.00 20.21 ? 300 LYS B C   1 
ATOM 6369 O O   . LYS B 1 316 ? 176.299 192.992 218.992 1.00 20.21 ? 300 LYS B O   1 
ATOM 6370 C CB  . LYS B 1 316 ? 177.274 192.240 216.163 1.00 20.21 ? 300 LYS B CB  1 
ATOM 6371 C CG  . LYS B 1 316 ? 177.789 190.860 216.534 1.00 20.21 ? 300 LYS B CG  1 
ATOM 6372 C CD  . LYS B 1 316 ? 179.295 190.866 216.737 1.00 20.21 ? 300 LYS B CD  1 
ATOM 6373 C CE  . LYS B 1 316 ? 179.754 189.624 217.483 1.00 20.21 ? 300 LYS B CE  1 
ATOM 6374 N NZ  . LYS B 1 316 ? 179.045 189.462 218.782 1.00 20.21 ? 300 LYS B NZ  1 
ATOM 6375 N N   . CYS B 1 317 ? 175.110 191.140 218.509 1.00 20.92 ? 301 CYS B N   1 
ATOM 6376 C CA  . CYS B 1 317 ? 174.976 190.692 219.884 1.00 20.92 ? 301 CYS B CA  1 
ATOM 6377 C C   . CYS B 1 317 ? 175.743 189.384 220.072 1.00 20.92 ? 301 CYS B C   1 
ATOM 6378 O O   . CYS B 1 317 ? 176.408 188.891 219.154 1.00 20.92 ? 301 CYS B O   1 
ATOM 6379 C CB  . CYS B 1 317 ? 173.496 190.543 220.247 1.00 20.92 ? 301 CYS B CB  1 
ATOM 6380 S SG  . CYS B 1 317 ? 172.640 192.106 220.552 1.00 20.92 ? 301 CYS B SG  1 
ATOM 6381 N N   . ASN B 1 318 ? 175.651 188.821 221.272 1.00 23.73 ? 302 ASN B N   1 
ATOM 6382 C CA  . ASN B 1 318 ? 176.311 187.559 221.582 1.00 23.73 ? 302 ASN B CA  1 
ATOM 6383 C C   . ASN B 1 318 ? 175.588 186.911 222.756 1.00 23.73 ? 302 ASN B C   1 
ATOM 6384 O O   . ASN B 1 318 ? 174.543 187.388 223.208 1.00 23.73 ? 302 ASN B O   1 
ATOM 6385 C CB  . ASN B 1 318 ? 177.798 187.766 221.878 1.00 23.73 ? 302 ASN B CB  1 
ATOM 6386 C CG  . ASN B 1 318 ? 178.655 186.618 221.381 1.00 23.73 ? 302 ASN B CG  1 
ATOM 6387 O OD1 . ASN B 1 318 ? 178.200 185.477 221.304 1.00 23.73 ? 302 ASN B OD1 1 
ATOM 6388 N ND2 . ASN B 1 318 ? 179.904 186.916 221.041 1.00 23.73 ? 302 ASN B ND2 1 
ATOM 6389 N N   . ASN B 1 319 ? 176.160 185.812 223.250 1.00 23.50 ? 303 ASN B N   1 
ATOM 6390 C CA  . ASN B 1 319 ? 175.503 185.031 224.293 1.00 23.50 ? 303 ASN B CA  1 
ATOM 6391 C C   . ASN B 1 319 ? 175.556 185.746 225.638 1.00 23.50 ? 303 ASN B C   1 
ATOM 6392 O O   . ASN B 1 319 ? 174.517 186.073 226.223 1.00 23.50 ? 303 ASN B O   1 
ATOM 6393 C CB  . ASN B 1 319 ? 176.146 183.646 224.388 1.00 23.50 ? 303 ASN B CB  1 
ATOM 6394 C CG  . ASN B 1 319 ? 175.577 182.816 225.523 1.00 23.50 ? 303 ASN B CG  1 
ATOM 6395 O OD1 . ASN B 1 319 ? 174.547 182.159 225.371 1.00 23.50 ? 303 ASN B OD1 1 
ATOM 6396 N ND2 . ASN B 1 319 ? 176.251 182.837 226.667 1.00 23.50 ? 303 ASN B ND2 1 
ATOM 6397 N N   . ALA B 1 320 ? 176.759 185.996 226.148 1.00 23.44 ? 304 ALA B N   1 
ATOM 6398 C CA  . ALA B 1 320 ? 176.941 186.582 227.471 1.00 23.44 ? 304 ALA B CA  1 
ATOM 6399 C C   . ALA B 1 320 ? 178.010 187.665 227.447 1.00 23.44 ? 304 ALA B C   1 
ATOM 6400 O O   . ALA B 1 320 ? 178.801 187.804 228.384 1.00 23.44 ? 304 ALA B O   1 
ATOM 6401 C CB  . ALA B 1 320 ? 177.286 185.509 228.500 1.00 23.44 ? 304 ALA B CB  1 
ATOM 6402 N N   . THR B 1 321 ? 178.053 188.454 226.371 1.00 21.92 ? 305 THR B N   1 
ATOM 6403 C CA  . THR B 1 321 ? 178.990 189.564 226.276 1.00 21.92 ? 305 THR B CA  1 
ATOM 6404 C C   . THR B 1 321 ? 178.330 190.930 226.382 1.00 21.92 ? 305 THR B C   1 
ATOM 6405 O O   . THR B 1 321 ? 179.044 191.924 226.544 1.00 21.92 ? 305 THR B O   1 
ATOM 6406 C CB  . THR B 1 321 ? 179.772 189.501 224.955 1.00 21.92 ? 305 THR B CB  1 
ATOM 6407 O OG1 . THR B 1 321 ? 178.932 189.936 223.880 1.00 21.92 ? 305 THR B OG1 1 
ATOM 6408 C CG2 . THR B 1 321 ? 180.245 188.081 224.683 1.00 21.92 ? 305 THR B CG2 1 
ATOM 6409 N N   . VAL B 1 322 ? 176.998 190.996 226.284 1.00 20.58 ? 306 VAL B N   1 
ATOM 6410 C CA  . VAL B 1 322 ? 176.188 192.211 226.396 1.00 20.58 ? 306 VAL B CA  1 
ATOM 6411 C C   . VAL B 1 322 ? 176.804 193.367 225.606 1.00 20.58 ? 306 VAL B C   1 
ATOM 6412 O O   . VAL B 1 322 ? 176.667 194.540 225.969 1.00 20.58 ? 306 VAL B O   1 
ATOM 6413 C CB  . VAL B 1 322 ? 175.941 192.568 227.883 1.00 20.58 ? 306 VAL B CB  1 
ATOM 6414 C CG1 . VAL B 1 322 ? 177.162 193.208 228.563 1.00 20.58 ? 306 VAL B CG1 1 
ATOM 6415 C CG2 . VAL B 1 322 ? 174.690 193.436 228.040 1.00 20.58 ? 306 VAL B CG2 1 
ATOM 6416 N N   . ASP B 1 323 ? 177.445 193.044 224.485 1.00 21.69 ? 307 ASP B N   1 
ATOM 6417 C CA  . ASP B 1 323 ? 178.064 194.033 223.615 1.00 21.69 ? 307 ASP B CA  1 
ATOM 6418 C C   . ASP B 1 323 ? 177.235 194.199 222.349 1.00 21.69 ? 307 ASP B C   1 
ATOM 6419 O O   . ASP B 1 323 ? 176.786 193.214 221.755 1.00 21.69 ? 307 ASP B O   1 
ATOM 6420 C CB  . ASP B 1 323 ? 179.496 193.630 223.251 1.00 21.69 ? 307 ASP B CB  1 
ATOM 6421 C CG  . ASP B 1 323 ? 180.441 193.705 224.435 1.00 21.69 ? 307 ASP B CG  1 
ATOM 6422 O OD1 . ASP B 1 323 ? 180.270 194.611 225.277 1.00 21.69 ? 307 ASP B OD1 1 
ATOM 6423 O OD2 . ASP B 1 323 ? 181.354 192.857 224.523 1.00 21.69 ? 307 ASP B OD2 1 
ATOM 6424 N N   . TRP B 1 324 ? 177.034 195.450 221.942 1.00 26.90 ? 308 TRP B N   1 
ATOM 6425 C CA  . TRP B 1 324 ? 176.265 195.796 220.750 1.00 26.90 ? 308 TRP B CA  1 
ATOM 6426 C C   . TRP B 1 324 ? 177.084 196.702 219.838 1.00 26.90 ? 308 TRP B C   1 
ATOM 6427 O O   . TRP B 1 324 ? 176.614 197.732 219.351 1.00 26.90 ? 308 TRP B O   1 
ATOM 6428 C CB  . TRP B 1 324 ? 174.934 196.445 221.129 1.00 26.90 ? 308 TRP B CB  1 
ATOM 6429 C CG  . TRP B 1 324 ? 175.059 197.687 221.969 1.00 26.90 ? 308 TRP B CG  1 
ATOM 6430 C CD1 . TRP B 1 324 ? 175.138 198.976 221.524 1.00 26.90 ? 308 TRP B CD1 1 
ATOM 6431 C CD2 . TRP B 1 324 ? 175.104 197.756 223.400 1.00 26.90 ? 308 TRP B CD2 1 
ATOM 6432 N NE1 . TRP B 1 324 ? 175.238 199.840 222.587 1.00 26.90 ? 308 TRP B NE1 1 
ATOM 6433 C CE2 . TRP B 1 324 ? 175.218 199.116 223.750 1.00 26.90 ? 308 TRP B CE2 1 
ATOM 6434 C CE3 . TRP B 1 324 ? 175.063 196.799 224.419 1.00 26.90 ? 308 TRP B CE3 1 
ATOM 6435 C CZ2 . TRP B 1 324 ? 175.291 199.543 225.074 1.00 26.90 ? 308 TRP B CZ2 1 
ATOM 6436 C CZ3 . TRP B 1 324 ? 175.135 197.226 225.733 1.00 26.90 ? 308 TRP B CZ3 1 
ATOM 6437 C CH2 . TRP B 1 324 ? 175.248 198.585 226.048 1.00 26.90 ? 308 TRP B CH2 1 
ATOM 6438 N N   . GLU B 1 325 ? 178.335 196.312 219.591 1.00 27.08 ? 309 GLU B N   1 
ATOM 6439 C CA  . GLU B 1 325 ? 179.239 197.126 218.787 1.00 27.08 ? 309 GLU B CA  1 
ATOM 6440 C C   . GLU B 1 325 ? 178.665 197.364 217.395 1.00 27.08 ? 309 GLU B C   1 
ATOM 6441 O O   . GLU B 1 325 ? 178.160 196.442 216.749 1.00 27.08 ? 309 GLU B O   1 
ATOM 6442 C CB  . GLU B 1 325 ? 180.607 196.451 218.688 1.00 27.08 ? 309 GLU B CB  1 
ATOM 6443 C CG  . GLU B 1 325 ? 180.550 194.974 218.333 1.00 27.08 ? 309 GLU B CG  1 
ATOM 6444 C CD  . GLU B 1 325 ? 181.904 194.299 218.432 1.00 27.08 ? 309 GLU B CD  1 
ATOM 6445 O OE1 . GLU B 1 325 ? 182.768 194.805 219.179 1.00 27.08 ? 309 GLU B OE1 1 
ATOM 6446 O OE2 . GLU B 1 325 ? 182.104 193.264 217.763 1.00 27.08 ? 309 GLU B OE2 1 
ATOM 6447 N N   . TRP B 1 326 ? 178.744 198.611 216.939 1.00 25.24 ? 310 TRP B N   1 
ATOM 6448 C CA  . TRP B 1 326 ? 178.181 199.010 215.657 1.00 25.24 ? 310 TRP B CA  1 
ATOM 6449 C C   . TRP B 1 326 ? 179.217 198.828 214.555 1.00 25.24 ? 310 TRP B C   1 
ATOM 6450 O O   . TRP B 1 326 ? 180.325 199.367 214.639 1.00 25.24 ? 310 TRP B O   1 
ATOM 6451 C CB  . TRP B 1 326 ? 177.706 200.463 215.712 1.00 25.24 ? 310 TRP B CB  1 
ATOM 6452 C CG  . TRP B 1 326 ? 177.652 201.142 214.379 1.00 25.24 ? 310 TRP B CG  1 
ATOM 6453 C CD1 . TRP B 1 326 ? 176.649 201.060 213.458 1.00 25.24 ? 310 TRP B CD1 1 
ATOM 6454 C CD2 . TRP B 1 326 ? 178.638 202.018 213.821 1.00 25.24 ? 310 TRP B CD2 1 
ATOM 6455 N NE1 . TRP B 1 326 ? 176.952 201.826 212.358 1.00 25.24 ? 310 TRP B NE1 1 
ATOM 6456 C CE2 . TRP B 1 326 ? 178.168 202.425 212.556 1.00 25.24 ? 310 TRP B CE2 1 
ATOM 6457 C CE3 . TRP B 1 326 ? 179.875 202.496 214.266 1.00 25.24 ? 310 TRP B CE3 1 
ATOM 6458 C CZ2 . TRP B 1 326 ? 178.890 203.285 211.732 1.00 25.24 ? 310 TRP B CZ2 1 
ATOM 6459 C CZ3 . TRP B 1 326 ? 180.590 203.350 213.447 1.00 25.24 ? 310 TRP B CZ3 1 
ATOM 6460 C CH2 . TRP B 1 326 ? 180.096 203.736 212.195 1.00 25.24 ? 310 TRP B CH2 1 
ATOM 6461 N N   . CYS B 1 327 ? 178.852 198.067 213.528 1.00 21.85 ? 311 CYS B N   1 
ATOM 6462 C CA  . CYS B 1 327 ? 179.735 197.769 212.415 1.00 21.85 ? 311 CYS B CA  1 
ATOM 6463 C C   . CYS B 1 327 ? 179.443 198.713 211.249 1.00 21.85 ? 311 CYS B C   1 
ATOM 6464 O O   . CYS B 1 327 ? 178.687 199.681 211.376 1.00 21.85 ? 311 CYS B O   1 
ATOM 6465 C CB  . CYS B 1 327 ? 179.590 196.300 212.016 1.00 21.85 ? 311 CYS B CB  1 
ATOM 6466 S SG  . CYS B 1 327 ? 180.567 195.168 213.030 1.00 21.85 ? 311 CYS B SG  1 
ATOM 6467 N N   . ALA B 1 328 ? 180.049 198.431 210.099 1.00 21.26 ? 312 ALA B N   1 
ATOM 6468 C CA  . ALA B 1 328 ? 179.897 199.303 208.944 1.00 21.26 ? 312 ALA B CA  1 
ATOM 6469 C C   . ALA B 1 328 ? 178.456 199.272 208.437 1.00 21.26 ? 312 ALA B C   1 
ATOM 6470 O O   . ALA B 1 328 ? 177.864 198.196 208.305 1.00 21.26 ? 312 ALA B O   1 
ATOM 6471 C CB  . ALA B 1 328 ? 180.852 198.887 207.828 1.00 21.26 ? 312 ALA B CB  1 
ATOM 6472 N N   . PRO B 1 329 ? 177.867 200.430 208.152 1.00 28.05 ? 313 PRO B N   1 
ATOM 6473 C CA  . PRO B 1 329 ? 176.499 200.457 207.626 1.00 28.05 ? 313 PRO B CA  1 
ATOM 6474 C C   . PRO B 1 329 ? 176.424 199.892 206.215 1.00 28.05 ? 313 PRO B C   1 
ATOM 6475 O O   . PRO B 1 329 ? 177.386 199.928 205.443 1.00 28.05 ? 313 PRO B O   1 
ATOM 6476 C CB  . PRO B 1 329 ? 176.141 201.947 207.645 1.00 28.05 ? 313 PRO B CB  1 
ATOM 6477 C CG  . PRO B 1 329 ? 177.458 202.646 207.567 1.00 28.05 ? 313 PRO B CG  1 
ATOM 6478 C CD  . PRO B 1 329 ? 178.418 201.784 208.334 1.00 28.05 ? 313 PRO B CD  1 
ATOM 6479 N N   . LEU B 1 330 ? 175.253 199.362 205.886 1.00 25.83 ? 314 LEU B N   1 
ATOM 6480 C CA  . LEU B 1 330 ? 175.027 198.822 204.550 1.00 25.83 ? 314 LEU B CA  1 
ATOM 6481 C C   . LEU B 1 330 ? 174.938 199.960 203.539 1.00 25.83 ? 314 LEU B C   1 
ATOM 6482 O O   . LEU B 1 330 ? 174.169 200.907 203.745 1.00 25.83 ? 314 LEU B O   1 
ATOM 6483 C CB  . LEU B 1 330 ? 173.751 197.986 204.517 1.00 25.83 ? 314 LEU B CB  1 
ATOM 6484 C CG  . LEU B 1 330 ? 173.718 196.761 205.433 1.00 25.83 ? 314 LEU B CG  1 
ATOM 6485 C CD1 . LEU B 1 330 ? 172.411 196.003 205.268 1.00 25.83 ? 314 LEU B CD1 1 
ATOM 6486 C CD2 . LEU B 1 330 ? 174.907 195.854 205.159 1.00 25.83 ? 314 LEU B CD2 1 
ATOM 6487 N N   . PRO B 1 331 ? 175.711 199.915 202.449 1.00 27.21 ? 315 PRO B N   1 
ATOM 6488 C CA  . PRO B 1 331 ? 175.633 201.002 201.456 1.00 27.21 ? 315 PRO B CA  1 
ATOM 6489 C C   . PRO B 1 331 ? 174.257 201.161 200.833 1.00 27.21 ? 315 PRO B C   1 
ATOM 6490 O O   . PRO B 1 331 ? 173.850 202.288 200.523 1.00 27.21 ? 315 PRO B O   1 
ATOM 6491 C CB  . PRO B 1 331 ? 176.689 200.598 200.415 1.00 27.21 ? 315 PRO B CB  1 
ATOM 6492 C CG  . PRO B 1 331 ? 176.870 199.124 200.598 1.00 27.21 ? 315 PRO B CG  1 
ATOM 6493 C CD  . PRO B 1 331 ? 176.677 198.874 202.062 1.00 27.21 ? 315 PRO B CD  1 
ATOM 6494 N N   . ARG B 1 332 ? 173.526 200.066 200.640 1.00 28.67 ? 316 ARG B N   1 
ATOM 6495 C CA  . ARG B 1 332 ? 172.193 200.100 200.047 1.00 28.67 ? 316 ARG B CA  1 
ATOM 6496 C C   . ARG B 1 332 ? 171.176 199.740 201.124 1.00 28.67 ? 316 ARG B C   1 
ATOM 6497 O O   . ARG B 1 332 ? 171.131 198.595 201.588 1.00 28.67 ? 316 ARG B O   1 
ATOM 6498 C CB  . ARG B 1 332 ? 172.104 199.147 198.857 1.00 28.67 ? 316 ARG B CB  1 
ATOM 6499 C CG  . ARG B 1 332 ? 173.017 199.521 197.701 1.00 28.67 ? 316 ARG B CG  1 
ATOM 6500 C CD  . ARG B 1 332 ? 172.769 198.651 196.479 1.00 28.67 ? 316 ARG B CD  1 
ATOM 6501 N NE  . ARG B 1 332 ? 171.390 198.743 196.015 1.00 28.67 ? 316 ARG B NE  1 
ATOM 6502 C CZ  . ARG B 1 332 ? 170.940 198.198 194.893 1.00 28.67 ? 316 ARG B CZ  1 
ATOM 6503 N NH1 . ARG B 1 332 ? 171.739 197.527 194.081 1.00 28.67 ? 316 ARG B NH1 1 
ATOM 6504 N NH2 . ARG B 1 332 ? 169.656 198.336 194.576 1.00 28.67 ? 316 ARG B NH2 1 
ATOM 6505 N N   . ASP B 1 333 ? 170.361 200.715 201.519 1.00 27.79 ? 317 ASP B N   1 
ATOM 6506 C CA  . ASP B 1 333 ? 169.384 200.492 202.575 1.00 27.79 ? 317 ASP B CA  1 
ATOM 6507 C C   . ASP B 1 333 ? 168.204 199.682 202.054 1.00 27.79 ? 317 ASP B C   1 
ATOM 6508 O O   . ASP B 1 333 ? 167.630 199.997 201.007 1.00 27.79 ? 317 ASP B O   1 
ATOM 6509 C CB  . ASP B 1 333 ? 168.899 201.823 203.143 1.00 27.79 ? 317 ASP B CB  1 
ATOM 6510 C CG  . ASP B 1 333 ? 169.938 202.493 204.016 1.00 27.79 ? 317 ASP B CG  1 
ATOM 6511 O OD1 . ASP B 1 333 ? 171.043 201.929 204.163 1.00 27.79 ? 317 ASP B OD1 1 
ATOM 6512 O OD2 . ASP B 1 333 ? 169.646 203.578 204.560 1.00 27.79 ? 317 ASP B OD2 1 
ATOM 6513 N N   . ARG B 1 334 ? 167.845 198.635 202.794 1.00 25.11 ? 318 ARG B N   1 
ATOM 6514 C CA  . ARG B 1 334 ? 166.732 197.765 202.452 1.00 25.11 ? 318 ARG B CA  1 
ATOM 6515 C C   . ARG B 1 334 ? 165.894 197.530 203.699 1.00 25.11 ? 318 ARG B C   1 
ATOM 6516 O O   . ARG B 1 334 ? 166.399 197.592 204.823 1.00 25.11 ? 318 ARG B O   1 
ATOM 6517 C CB  . ARG B 1 334 ? 167.212 196.418 201.892 1.00 25.11 ? 318 ARG B CB  1 
ATOM 6518 C CG  . ARG B 1 334 ? 168.472 196.510 201.057 1.00 25.11 ? 318 ARG B CG  1 
ATOM 6519 C CD  . ARG B 1 334 ? 169.272 195.229 201.132 1.00 25.11 ? 318 ARG B CD  1 
ATOM 6520 N NE  . ARG B 1 334 ? 170.468 195.309 200.304 1.00 25.11 ? 318 ARG B NE  1 
ATOM 6521 C CZ  . ARG B 1 334 ? 171.156 194.261 199.873 1.00 25.11 ? 318 ARG B CZ  1 
ATOM 6522 N NH1 . ARG B 1 334 ? 170.793 193.026 200.173 1.00 25.11 ? 318 ARG B NH1 1 
ATOM 6523 N NH2 . ARG B 1 334 ? 172.237 194.459 199.125 1.00 25.11 ? 318 ARG B NH2 1 
ATOM 6524 N N   . LEU B 1 335 ? 164.610 197.260 203.491 1.00 25.17 ? 319 LEU B N   1 
ATOM 6525 C CA  . LEU B 1 335 ? 163.690 196.955 204.576 1.00 25.17 ? 319 LEU B CA  1 
ATOM 6526 C C   . LEU B 1 335 ? 163.061 195.590 204.341 1.00 25.17 ? 319 LEU B C   1 
ATOM 6527 O O   . LEU B 1 335 ? 162.714 195.245 203.207 1.00 25.17 ? 319 LEU B O   1 
ATOM 6528 C CB  . LEU B 1 335 ? 162.598 198.021 204.699 1.00 25.17 ? 319 LEU B CB  1 
ATOM 6529 C CG  . LEU B 1 335 ? 162.045 198.224 206.112 1.00 25.17 ? 319 LEU B CG  1 
ATOM 6530 C CD1 . LEU B 1 335 ? 163.122 198.766 207.042 1.00 25.17 ? 319 LEU B CD1 1 
ATOM 6531 C CD2 . LEU B 1 335 ? 160.834 199.144 206.090 1.00 25.17 ? 319 LEU B CD2 1 
ATOM 6532 N N   . GLN B 1 336 ? 162.928 194.814 205.418 1.00 26.22 ? 320 GLN B N   1 
ATOM 6533 C CA  . GLN B 1 336 ? 162.316 193.487 205.376 1.00 26.22 ? 320 GLN B CA  1 
ATOM 6534 C C   . GLN B 1 336 ? 163.021 192.586 204.359 1.00 26.22 ? 320 GLN B C   1 
ATOM 6535 O O   . GLN B 1 336 ? 162.433 192.117 203.383 1.00 26.22 ? 320 GLN B O   1 
ATOM 6536 C CB  . GLN B 1 336 ? 160.815 193.587 205.083 1.00 26.22 ? 320 GLN B CB  1 
ATOM 6537 C CG  . GLN B 1 336 ? 160.011 192.382 205.542 1.00 26.22 ? 320 GLN B CG  1 
ATOM 6538 C CD  . GLN B 1 336 ? 159.989 192.237 207.050 1.00 26.22 ? 320 GLN B CD  1 
ATOM 6539 O OE1 . GLN B 1 336 ? 160.074 193.224 207.780 1.00 26.22 ? 320 GLN B OE1 1 
ATOM 6540 N NE2 . GLN B 1 336 ? 159.875 191.002 207.524 1.00 26.22 ? 320 GLN B NE2 1 
ATOM 6541 N N   . HIS B 1 337 ? 164.307 192.359 204.606 1.00 26.23 ? 321 HIS B N   1 
ATOM 6542 C CA  . HIS B 1 337 ? 165.122 191.494 203.770 1.00 26.23 ? 321 HIS B CA  1 
ATOM 6543 C C   . HIS B 1 337 ? 165.407 190.183 204.501 1.00 26.23 ? 321 HIS B C   1 
ATOM 6544 O O   . HIS B 1 337 ? 165.039 189.992 205.662 1.00 26.23 ? 321 HIS B O   1 
ATOM 6545 C CB  . HIS B 1 337 ? 166.417 192.200 203.358 1.00 26.23 ? 321 HIS B CB  1 
ATOM 6546 C CG  . HIS B 1 337 ? 167.226 192.721 204.506 1.00 26.23 ? 321 HIS B CG  1 
ATOM 6547 N ND1 . HIS B 1 337 ? 168.460 193.310 204.335 1.00 26.23 ? 321 HIS B ND1 1 
ATOM 6548 C CD2 . HIS B 1 337 ? 166.984 192.738 205.839 1.00 26.23 ? 321 HIS B CD2 1 
ATOM 6549 C CE1 . HIS B 1 337 ? 168.941 193.671 205.511 1.00 26.23 ? 321 HIS B CE1 1 
ATOM 6550 N NE2 . HIS B 1 337 ? 168.065 193.335 206.440 1.00 26.23 ? 321 HIS B NE2 1 
ATOM 6551 N N   . THR B 1 338 ? 166.073 189.266 203.804 1.00 17.96 ? 322 THR B N   1 
ATOM 6552 C CA  . THR B 1 338 ? 166.343 187.928 204.310 1.00 17.96 ? 322 THR B CA  1 
ATOM 6553 C C   . THR B 1 338 ? 167.813 187.806 204.685 1.00 17.96 ? 322 THR B C   1 
ATOM 6554 O O   . THR B 1 338 ? 168.692 188.121 203.875 1.00 17.96 ? 322 THR B O   1 
ATOM 6555 C CB  . THR B 1 338 ? 165.981 186.869 203.268 1.00 17.96 ? 322 THR B CB  1 
ATOM 6556 O OG1 . THR B 1 338 ? 166.938 186.902 202.203 1.00 17.96 ? 322 THR B OG1 1 
ATOM 6557 C CG2 . THR B 1 338 ? 164.599 187.141 202.698 1.00 17.96 ? 322 THR B CG2 1 
ATOM 6558 N N   . LEU B 1 339 ? 168.076 187.348 205.905 1.00 15.85 ? 323 LEU B N   1 
ATOM 6559 C CA  . LEU B 1 339 ? 169.430 187.126 206.395 1.00 15.85 ? 323 LEU B CA  1 
ATOM 6560 C C   . LEU B 1 339 ? 169.645 185.638 206.627 1.00 15.85 ? 323 LEU B C   1 
ATOM 6561 O O   . LEU B 1 339 ? 168.877 185.002 207.357 1.00 15.85 ? 323 LEU B O   1 
ATOM 6562 C CB  . LEU B 1 339 ? 169.683 187.901 207.689 1.00 15.85 ? 323 LEU B CB  1 
ATOM 6563 C CG  . LEU B 1 339 ? 169.437 189.408 207.667 1.00 15.85 ? 323 LEU B CG  1 
ATOM 6564 C CD1 . LEU B 1 339 ? 169.748 190.011 209.026 1.00 15.85 ? 323 LEU B CD1 1 
ATOM 6565 C CD2 . LEU B 1 339 ? 170.270 190.069 206.587 1.00 15.85 ? 323 LEU B CD2 1 
ATOM 6566 N N   . VAL B 1 340 ? 170.684 185.086 206.005 1.00 13.34 ? 324 VAL B N   1 
ATOM 6567 C CA  . VAL B 1 340 ? 171.032 183.675 206.135 1.00 13.34 ? 324 VAL B CA  1 
ATOM 6568 C C   . VAL B 1 340 ? 172.527 183.579 206.410 1.00 13.34 ? 324 VAL B C   1 
ATOM 6569 O O   . VAL B 1 340 ? 173.303 184.426 205.951 1.00 13.34 ? 324 VAL B O   1 
ATOM 6570 C CB  . VAL B 1 340 ? 170.653 182.865 204.882 1.00 13.34 ? 324 VAL B CB  1 
ATOM 6571 C CG1 . VAL B 1 340 ? 169.183 183.053 204.548 1.00 13.34 ? 324 VAL B CG1 1 
ATOM 6572 C CG2 . VAL B 1 340 ? 171.506 183.280 203.703 1.00 13.34 ? 324 VAL B CG2 1 
ATOM 6573 N N   . SER B 1 341 ? 172.924 182.527 207.128 1.00 12.61 ? 325 SER B N   1 
ATOM 6574 C CA  . SER B 1 341 ? 174.362 182.335 207.443 1.00 12.61 ? 325 SER B CA  1 
ATOM 6575 C C   . SER B 1 341 ? 174.884 181.093 206.722 1.00 12.61 ? 325 SER B C   1 
ATOM 6576 O O   . SER B 1 341 ? 174.416 179.992 207.050 1.00 12.61 ? 325 SER B O   1 
ATOM 6577 C CB  . SER B 1 341 ? 174.580 182.222 208.925 1.00 12.61 ? 325 SER B CB  1 
ATOM 6578 O OG  . SER B 1 341 ? 173.702 181.258 209.487 1.00 12.61 ? 325 SER B OG  1 
ATOM 6579 N N   . VAL B 1 342 ? 175.802 181.273 205.772 1.00 17.22 ? 326 VAL B N   1 
ATOM 6580 C CA  . VAL B 1 342 ? 176.436 180.104 205.096 1.00 17.22 ? 326 VAL B CA  1 
ATOM 6581 C C   . VAL B 1 342 ? 177.870 179.995 205.618 1.00 17.22 ? 326 VAL B C   1 
ATOM 6582 O O   . VAL B 1 342 ? 178.769 180.611 205.011 1.00 17.22 ? 326 VAL B O   1 
ATOM 6583 C CB  . VAL B 1 342 ? 176.409 180.263 203.567 1.00 17.22 ? 326 VAL B CB  1 
ATOM 6584 C CG1 . VAL B 1 342 ? 175.490 179.250 202.910 1.00 17.22 ? 326 VAL B CG1 1 
ATOM 6585 C CG2 . VAL B 1 342 ? 176.032 181.680 203.166 1.00 17.22 ? 326 VAL B CG2 1 
ATOM 6586 N N   . PRO B 1 343 ? 178.132 179.240 206.707 1.00 23.42 ? 327 PRO B N   1 
ATOM 6587 C CA  . PRO B 1 343 ? 179.472 179.178 207.302 1.00 23.42 ? 327 PRO B CA  1 
ATOM 6588 C C   . PRO B 1 343 ? 180.573 178.944 206.259 1.00 23.42 ? 327 PRO B C   1 
ATOM 6589 O O   . PRO B 1 343 ? 181.673 179.412 206.476 1.00 23.42 ? 327 PRO B O   1 
ATOM 6590 C CB  . PRO B 1 343 ? 179.374 177.967 208.240 1.00 23.42 ? 327 PRO B CB  1 
ATOM 6591 C CG  . PRO B 1 343 ? 177.920 177.948 208.649 1.00 23.42 ? 327 PRO B CG  1 
ATOM 6592 C CD  . PRO B 1 343 ? 177.171 178.385 207.408 1.00 23.42 ? 327 PRO B CD  1 
ATOM 6593 N N   . GLY B 1 344 ? 180.259 178.235 205.170 1.00 19.05 ? 328 GLY B N   1 
ATOM 6594 C CA  . GLY B 1 344 ? 181.245 177.984 204.102 1.00 19.05 ? 328 GLY B CA  1 
ATOM 6595 C C   . GLY B 1 344 ? 182.195 179.155 203.917 1.00 19.05 ? 328 GLY B C   1 
ATOM 6596 O O   . GLY B 1 344 ? 183.419 178.920 203.894 1.00 19.05 ? 328 GLY B O   1 
ATOM 6597 N N   . LYS B 1 345 ? 181.656 180.371 203.789 1.00 21.61 ? 329 LYS B N   1 
ATOM 6598 C CA  . LYS B 1 345 ? 182.500 181.580 203.584 1.00 21.61 ? 329 LYS B CA  1 
ATOM 6599 C C   . LYS B 1 345 ? 182.261 182.587 204.717 1.00 21.61 ? 329 LYS B C   1 
ATOM 6600 O O   . LYS B 1 345 ? 182.355 183.797 204.435 1.00 21.61 ? 329 LYS B O   1 
ATOM 6601 C CB  . LYS B 1 345 ? 182.196 182.218 202.224 1.00 21.61 ? 329 LYS B CB  1 
ATOM 6602 C CG  . LYS B 1 345 ? 181.280 181.411 201.313 1.00 21.61 ? 329 LYS B CG  1 
ATOM 6603 C CD  . LYS B 1 345 ? 179.819 181.780 201.442 1.00 21.61 ? 329 LYS B CD  1 
ATOM 6604 C CE  . LYS B 1 345 ? 178.898 180.742 200.839 1.00 21.61 ? 329 LYS B CE  1 
ATOM 6605 N NZ  . LYS B 1 345 ? 179.128 179.401 201.425 1.00 21.61 ? 329 LYS B NZ  1 
ATOM 6606 N N   . ASP B 1 346 ? 181.972 182.111 205.936 1.00 21.82 ? 330 ASP B N   1 
ATOM 6607 C CA  . ASP B 1 346 ? 181.742 182.990 207.082 1.00 21.82 ? 330 ASP B CA  1 
ATOM 6608 C C   . ASP B 1 346 ? 181.082 184.288 206.620 1.00 21.82 ? 330 ASP B C   1 
ATOM 6609 O O   . ASP B 1 346 ? 181.651 185.378 206.707 1.00 21.82 ? 330 ASP B O   1 
ATOM 6610 C CB  . ASP B 1 346 ? 183.047 183.254 207.840 1.00 21.82 ? 330 ASP B CB  1 
ATOM 6611 C CG  . ASP B 1 346 ? 182.825 183.939 209.178 1.00 21.82 ? 330 ASP B CG  1 
ATOM 6612 O OD1 . ASP B 1 346 ? 182.952 183.260 210.218 1.00 21.82 ? 330 ASP B OD1 1 
ATOM 6613 O OD2 . ASP B 1 346 ? 182.544 185.155 209.198 1.00 21.82 ? 330 ASP B OD2 1 
ATOM 6614 N N   . ALA B 1 347 ? 179.871 184.155 206.087 1.00 18.05 ? 331 ALA B N   1 
ATOM 6615 C CA  . ALA B 1 347 ? 179.167 185.258 205.455 1.00 18.05 ? 331 ALA B CA  1 
ATOM 6616 C C   . ALA B 1 347 ? 177.745 185.364 205.988 1.00 18.05 ? 331 ALA B C   1 
ATOM 6617 O O   . ALA B 1 347 ? 177.179 184.396 206.504 1.00 18.05 ? 331 ALA B O   1 
ATOM 6618 C CB  . ALA B 1 347 ? 179.142 185.095 203.932 1.00 18.05 ? 331 ALA B CB  1 
ATOM 6619 N N   . ILE B 1 348 ? 177.178 186.562 205.857 1.00 14.15 ? 332 ILE B N   1 
ATOM 6620 C CA  . ILE B 1 348 ? 175.853 186.893 206.373 1.00 14.15 ? 332 ILE B CA  1 
ATOM 6621 C C   . ILE B 1 348 ? 174.974 187.352 205.215 1.00 14.15 ? 332 ILE B C   1 
ATOM 6622 O O   . ILE B 1 348 ? 174.207 188.312 205.351 1.00 14.15 ? 332 ILE B O   1 
ATOM 6623 C CB  . ILE B 1 348 ? 175.929 187.952 207.490 1.00 14.15 ? 332 ILE B CB  1 
ATOM 6624 C CG1 . ILE B 1 348 ? 177.094 187.653 208.432 1.00 14.15 ? 332 ILE B CG1 1 
ATOM 6625 C CG2 . ILE B 1 348 ? 174.649 187.964 208.315 1.00 14.15 ? 332 ILE B CG2 1 
ATOM 6626 C CD1 . ILE B 1 348 ? 176.952 186.350 209.189 1.00 14.15 ? 332 ILE B CD1 1 
ATOM 6627 N N   . TYR B 1 349 ? 175.127 186.702 204.057 1.00 18.80 ? 333 TYR B N   1 
ATOM 6628 C CA  . TYR B 1 349 ? 174.444 187.047 202.811 1.00 18.80 ? 333 TYR B CA  1 
ATOM 6629 C C   . TYR B 1 349 ? 173.031 187.561 203.048 1.00 18.80 ? 333 TYR B C   1 
ATOM 6630 O O   . TYR B 1 349 ? 172.209 186.890 203.680 1.00 18.80 ? 333 TYR B O   1 
ATOM 6631 C CB  . TYR B 1 349 ? 174.383 185.816 201.902 1.00 18.80 ? 333 TYR B CB  1 
ATOM 6632 C CG  . TYR B 1 349 ? 175.604 185.567 201.049 1.00 18.80 ? 333 TYR B CG  1 
ATOM 6633 C CD1 . TYR B 1 349 ? 176.641 184.765 201.501 1.00 18.80 ? 333 TYR B CD1 1 
ATOM 6634 C CD2 . TYR B 1 349 ? 175.705 186.112 199.776 1.00 18.80 ? 333 TYR B CD2 1 
ATOM 6635 C CE1 . TYR B 1 349 ? 177.753 184.526 200.718 1.00 18.80 ? 333 TYR B CE1 1 
ATOM 6636 C CE2 . TYR B 1 349 ? 176.812 185.879 198.985 1.00 18.80 ? 333 TYR B CE2 1 
ATOM 6637 C CZ  . TYR B 1 349 ? 177.833 185.086 199.461 1.00 18.80 ? 333 TYR B CZ  1 
ATOM 6638 O OH  . TYR B 1 349 ? 178.938 184.852 198.675 1.00 18.80 ? 333 TYR B OH  1 
ATOM 6639 N N   . SER B 1 350 ? 172.751 188.758 202.538 1.00 18.78 ? 334 SER B N   1 
ATOM 6640 C CA  . SER B 1 350 ? 171.451 189.410 202.683 1.00 18.78 ? 334 SER B CA  1 
ATOM 6641 C C   . SER B 1 350 ? 170.802 189.485 201.304 1.00 18.78 ? 334 SER B C   1 
ATOM 6642 O O   . SER B 1 350 ? 170.959 190.460 200.569 1.00 18.78 ? 334 SER B O   1 
ATOM 6643 C CB  . SER B 1 350 ? 171.608 190.798 203.312 1.00 18.78 ? 334 SER B CB  1 
ATOM 6644 O OG  . SER B 1 350 ? 170.352 191.441 203.445 1.00 18.78 ? 334 SER B OG  1 
ATOM 6645 N N   . LEU B 1 351 ? 170.058 188.439 200.958 1.00 19.45 ? 335 LEU B N   1 
ATOM 6646 C CA  . LEU B 1 351 ? 169.432 188.359 199.647 1.00 19.45 ? 335 LEU B CA  1 
ATOM 6647 C C   . LEU B 1 351 ? 168.055 189.013 199.659 1.00 19.45 ? 335 LEU B C   1 
ATOM 6648 O O   . LEU B 1 351 ? 167.294 188.895 200.623 1.00 19.45 ? 335 LEU B O   1 
ATOM 6649 C CB  . LEU B 1 351 ? 169.315 186.902 199.199 1.00 19.45 ? 335 LEU B CB  1 
ATOM 6650 C CG  . LEU B 1 351 ? 170.504 186.326 198.425 1.00 19.45 ? 335 LEU B CG  1 
ATOM 6651 C CD1 . LEU B 1 351 ? 171.686 186.071 199.349 1.00 19.45 ? 335 LEU B CD1 1 
ATOM 6652 C CD2 . LEU B 1 351 ? 170.109 185.053 197.693 1.00 19.45 ? 335 LEU B CD2 1 
ATOM 6653 N N   . GLY B 1 352 ? 167.741 189.710 198.567 1.00 21.59 ? 336 GLY B N   1 
ATOM 6654 C CA  . GLY B 1 352 ? 166.450 190.358 198.420 1.00 21.59 ? 336 GLY B CA  1 
ATOM 6655 C C   . GLY B 1 352 ? 166.318 191.594 199.298 1.00 21.59 ? 336 GLY B C   1 
ATOM 6656 O O   . GLY B 1 352 ? 167.285 192.093 199.881 1.00 21.59 ? 336 GLY B O   1 
ATOM 6657 N N   . GLY B 1 353 ? 165.084 192.092 199.385 1.00 24.49 ? 337 GLY B N   1 
ATOM 6658 C CA  . GLY B 1 353 ? 164.754 193.220 200.227 1.00 24.49 ? 337 GLY B CA  1 
ATOM 6659 C C   . GLY B 1 353 ? 163.736 194.130 199.576 1.00 24.49 ? 337 GLY B C   1 
ATOM 6660 O O   . GLY B 1 353 ? 163.266 193.888 198.459 1.00 24.49 ? 337 GLY B O   1 
ATOM 6661 N N   . LYS B 1 354 ? 163.396 195.203 200.289 1.00 21.23 ? 338 LYS B N   1 
ATOM 6662 C CA  . LYS B 1 354 ? 162.410 196.178 199.839 1.00 21.23 ? 338 LYS B CA  1 
ATOM 6663 C C   . LYS B 1 354 ? 163.038 197.561 199.916 1.00 21.23 ? 338 LYS B C   1 
ATOM 6664 O O   . LYS B 1 354 ? 163.711 197.881 200.900 1.00 21.23 ? 338 LYS B O   1 
ATOM 6665 C CB  . LYS B 1 354 ? 161.147 196.130 200.709 1.00 21.23 ? 338 LYS B CB  1 
ATOM 6666 C CG  . LYS B 1 354 ? 159.912 196.844 200.159 1.00 21.23 ? 338 LYS B CG  1 
ATOM 6667 C CD  . LYS B 1 354 ? 159.796 196.812 198.643 1.00 21.23 ? 338 LYS B CD  1 
ATOM 6668 C CE  . LYS B 1 354 ? 159.440 195.411 198.159 1.00 21.23 ? 338 LYS B CE  1 
ATOM 6669 N NZ  . LYS B 1 354 ? 158.919 195.415 196.768 1.00 21.23 ? 338 LYS B NZ  1 
ATOM 6670 N N   . THR B 1 355 ? 162.818 198.372 198.887 1.00 23.44 ? 339 THR B N   1 
ATOM 6671 C CA  . THR B 1 355 ? 163.325 199.736 198.866 1.00 23.44 ? 339 THR B CA  1 
ATOM 6672 C C   . THR B 1 355 ? 162.190 200.727 199.096 1.00 23.44 ? 339 THR B C   1 
ATOM 6673 O O   . THR B 1 355 ? 161.060 200.528 198.643 1.00 23.44 ? 339 THR B O   1 
ATOM 6674 C CB  . THR B 1 355 ? 164.023 200.036 197.538 1.00 23.44 ? 339 THR B CB  1 
ATOM 6675 O OG1 . THR B 1 355 ? 164.765 198.884 197.117 1.00 23.44 ? 339 THR B OG1 1 
ATOM 6676 C CG2 . THR B 1 355 ? 164.973 201.213 197.689 1.00 23.44 ? 339 THR B CG2 1 
ATOM 6677 N N   . LEU B 1 356 ? 162.503 201.806 199.816 1.00 24.75 ? 340 LEU B N   1 
ATOM 6678 C CA  . LEU B 1 356 ? 161.485 202.790 200.165 1.00 24.75 ? 340 LEU B CA  1 
ATOM 6679 C C   . LEU B 1 356 ? 161.120 203.699 198.999 1.00 24.75 ? 340 LEU B C   1 
ATOM 6680 O O   . LEU B 1 356 ? 160.089 204.377 199.061 1.00 24.75 ? 340 LEU B O   1 
ATOM 6681 C CB  . LEU B 1 356 ? 161.949 203.639 201.352 1.00 24.75 ? 340 LEU B CB  1 
ATOM 6682 C CG  . LEU B 1 356 ? 162.621 202.935 202.535 1.00 24.75 ? 340 LEU B CG  1 
ATOM 6683 C CD1 . LEU B 1 356 ? 164.134 202.860 202.358 1.00 24.75 ? 340 LEU B CD1 1 
ATOM 6684 C CD2 . LEU B 1 356 ? 162.266 203.631 203.840 1.00 24.75 ? 340 LEU B CD2 1 
ATOM 6685 N N   . GLN B 1 357 ? 161.933 203.732 197.943 1.00 24.70 ? 341 GLN B N   1 
ATOM 6686 C CA  . GLN B 1 357 ? 161.684 204.640 196.830 1.00 24.70 ? 341 GLN B CA  1 
ATOM 6687 C C   . GLN B 1 357 ? 160.800 203.998 195.767 1.00 24.70 ? 341 GLN B C   1 
ATOM 6688 O O   . GLN B 1 357 ? 161.142 204.009 194.580 1.00 24.70 ? 341 GLN B O   1 
ATOM 6689 C CB  . GLN B 1 357 ? 163.008 205.094 196.212 1.00 24.70 ? 341 GLN B CB  1 
ATOM 6690 C CG  . GLN B 1 357 ? 162.952 206.465 195.560 1.00 24.70 ? 341 GLN B CG  1 
ATOM 6691 C CD  . GLN B 1 357 ? 164.248 206.833 194.865 1.00 24.70 ? 341 GLN B CD  1 
ATOM 6692 O OE1 . GLN B 1 357 ? 165.242 206.113 194.959 1.00 24.70 ? 341 GLN B OE1 1 
ATOM 6693 N NE2 . GLN B 1 357 ? 164.243 207.960 194.164 1.00 24.70 ? 341 GLN B NE2 1 
ATOM 6694 N N   . ASP B 1 358 ? 159.657 203.449 196.188 1.00 21.27 ? 342 ASP B N   1 
ATOM 6695 C CA  . ASP B 1 358 ? 158.675 202.854 195.277 1.00 21.27 ? 342 ASP B CA  1 
ATOM 6696 C C   . ASP B 1 358 ? 159.319 201.821 194.355 1.00 21.27 ? 342 ASP B C   1 
ATOM 6697 O O   . ASP B 1 358 ? 159.011 201.739 193.164 1.00 21.27 ? 342 ASP B O   1 
ATOM 6698 C CB  . ASP B 1 358 ? 157.953 203.933 194.469 1.00 21.27 ? 342 ASP B CB  1 
ATOM 6699 C CG  . ASP B 1 358 ? 156.682 204.413 195.143 1.00 21.27 ? 342 ASP B CG  1 
ATOM 6700 O OD1 . ASP B 1 358 ? 155.944 203.568 195.691 1.00 21.27 ? 342 ASP B OD1 1 
ATOM 6701 O OD2 . ASP B 1 358 ? 156.421 205.634 195.124 1.00 21.27 ? 342 ASP B OD2 1 
ATOM 6702 N N   . THR B 1 359 ? 160.223 201.023 194.916 1.00 21.81 ? 343 THR B N   1 
ATOM 6703 C CA  . THR B 1 359 ? 160.919 199.992 194.160 1.00 21.81 ? 343 THR B CA  1 
ATOM 6704 C C   . THR B 1 359 ? 161.391 198.918 195.127 1.00 21.81 ? 343 THR B C   1 
ATOM 6705 O O   . THR B 1 359 ? 161.239 199.041 196.344 1.00 21.81 ? 343 THR B O   1 
ATOM 6706 C CB  . THR B 1 359 ? 162.102 200.562 193.365 1.00 21.81 ? 343 THR B CB  1 
ATOM 6707 O OG1 . THR B 1 359 ? 162.821 199.492 192.738 1.00 21.81 ? 343 THR B OG1 1 
ATOM 6708 C CG2 . THR B 1 359 ? 163.041 201.334 194.278 1.00 21.81 ? 343 THR B CG2 1 
ATOM 6709 N N   . LEU B 1 360 ? 161.950 197.849 194.569 1.00 22.41 ? 344 LEU B N   1 
ATOM 6710 C CA  . LEU B 1 360 ? 162.411 196.706 195.346 1.00 22.41 ? 344 LEU B CA  1 
ATOM 6711 C C   . LEU B 1 360 ? 163.889 196.459 195.073 1.00 22.41 ? 344 LEU B C   1 
ATOM 6712 O O   . LEU B 1 360 ? 164.350 196.605 193.936 1.00 22.41 ? 344 LEU B O   1 
ATOM 6713 C CB  . LEU B 1 360 ? 161.565 195.469 195.024 1.00 22.41 ? 344 LEU B CB  1 
ATOM 6714 C CG  . LEU B 1 360 ? 161.835 194.549 193.830 1.00 22.41 ? 344 LEU B CG  1 
ATOM 6715 C CD1 . LEU B 1 360 ? 162.884 193.485 194.138 1.00 22.41 ? 344 LEU B CD1 1 
ATOM 6716 C CD2 . LEU B 1 360 ? 160.530 193.917 193.363 1.00 22.41 ? 344 LEU B CD2 1 
ATOM 6717 N N   . SER B 1 361 ? 164.625 196.093 196.118 1.00 24.10 ? 345 SER B N   1 
ATOM 6718 C CA  . SER B 1 361 ? 166.052 195.855 195.988 1.00 24.10 ? 345 SER B CA  1 
ATOM 6719 C C   . SER B 1 361 ? 166.328 194.412 195.575 1.00 24.10 ? 345 SER B C   1 
ATOM 6720 O O   . SER B 1 361 ? 165.591 193.483 195.918 1.00 24.10 ? 345 SER B O   1 
ATOM 6721 C CB  . SER B 1 361 ? 166.771 196.171 197.299 1.00 24.10 ? 345 SER B CB  1 
ATOM 6722 O OG  . SER B 1 361 ? 168.114 195.723 197.261 1.00 24.10 ? 345 SER B OG  1 
ATOM 6723 N N   . ASN B 1 362 ? 167.420 194.234 194.824 1.00 24.07 ? 346 ASN B N   1 
ATOM 6724 C CA  . ASN B 1 362 ? 167.842 192.907 194.391 1.00 24.07 ? 346 ASN B CA  1 
ATOM 6725 C C   . ASN B 1 362 ? 169.317 192.646 194.671 1.00 24.07 ? 346 ASN B C   1 
ATOM 6726 O O   . ASN B 1 362 ? 169.825 191.586 194.284 1.00 24.07 ? 346 ASN B O   1 
ATOM 6727 C CB  . ASN B 1 362 ? 167.565 192.711 192.895 1.00 24.07 ? 346 ASN B CB  1 
ATOM 6728 C CG  . ASN B 1 362 ? 166.087 192.756 192.564 1.00 24.07 ? 346 ASN B CG  1 
ATOM 6729 O OD1 . ASN B 1 362 ? 165.402 191.733 192.580 1.00 24.07 ? 346 ASN B OD1 1 
ATOM 6730 N ND2 . ASN B 1 362 ? 165.587 193.947 192.257 1.00 24.07 ? 346 ASN B ND2 1 
ATOM 6731 N N   . ALA B 1 363 ? 170.019 193.570 195.319 1.00 24.18 ? 347 ALA B N   1 
ATOM 6732 C CA  . ALA B 1 363 ? 171.434 193.391 195.603 1.00 24.18 ? 347 ALA B CA  1 
ATOM 6733 C C   . ALA B 1 363 ? 171.637 192.511 196.829 1.00 24.18 ? 347 ALA B C   1 
ATOM 6734 O O   . ALA B 1 363 ? 170.706 192.251 197.598 1.00 24.18 ? 347 ALA B O   1 
ATOM 6735 C CB  . ALA B 1 363 ? 172.114 194.742 195.822 1.00 24.18 ? 347 ALA B CB  1 
ATOM 6736 N N   . VAL B 1 364 ? 172.874 192.050 197.006 1.00 17.77 ? 348 VAL B N   1 
ATOM 6737 C CA  . VAL B 1 364 ? 173.269 191.258 198.164 1.00 17.77 ? 348 VAL B CA  1 
ATOM 6738 C C   . VAL B 1 364 ? 174.505 191.895 198.784 1.00 17.77 ? 348 VAL B C   1 
ATOM 6739 O O   . VAL B 1 364 ? 175.362 192.427 198.070 1.00 17.77 ? 348 VAL B O   1 
ATOM 6740 C CB  . VAL B 1 364 ? 173.535 189.784 197.796 1.00 17.77 ? 348 VAL B CB  1 
ATOM 6741 C CG1 . VAL B 1 364 ? 172.390 189.227 196.966 1.00 17.77 ? 348 VAL B CG1 1 
ATOM 6742 C CG2 . VAL B 1 364 ? 174.847 189.634 197.049 1.00 17.77 ? 348 VAL B CG2 1 
ATOM 6743 N N   . ILE B 1 365 ? 174.574 191.880 200.114 1.00 20.14 ? 349 ILE B N   1 
ATOM 6744 C CA  . ILE B 1 365 ? 175.733 192.360 200.859 1.00 20.14 ? 349 ILE B CA  1 
ATOM 6745 C C   . ILE B 1 365 ? 176.028 191.351 201.958 1.00 20.14 ? 349 ILE B C   1 
ATOM 6746 O O   . ILE B 1 365 ? 175.223 191.184 202.882 1.00 20.14 ? 349 ILE B O   1 
ATOM 6747 C CB  . ILE B 1 365 ? 175.506 193.757 201.461 1.00 20.14 ? 349 ILE B CB  1 
ATOM 6748 C CG1 . ILE B 1 365 ? 175.201 194.778 200.363 1.00 20.14 ? 349 ILE B CG1 1 
ATOM 6749 C CG2 . ILE B 1 365 ? 176.719 194.191 202.267 1.00 20.14 ? 349 ILE B CG2 1 
ATOM 6750 C CD1 . ILE B 1 365 ? 174.652 196.088 200.880 1.00 20.14 ? 349 ILE B CD1 1 
ATOM 6751 N N   . TYR B 1 366 ? 177.177 190.686 201.867 1.00 17.67 ? 350 TYR B N   1 
ATOM 6752 C CA  . TYR B 1 366 ? 177.575 189.677 202.847 1.00 17.67 ? 350 TYR B CA  1 
ATOM 6753 C C   . TYR B 1 366 ? 178.651 190.278 203.747 1.00 17.67 ? 350 TYR B C   1 
ATOM 6754 O O   . TYR B 1 366 ? 179.831 190.316 203.390 1.00 17.67 ? 350 TYR B O   1 
ATOM 6755 C CB  . TYR B 1 366 ? 178.040 188.388 202.168 1.00 17.67 ? 350 TYR B CB  1 
ATOM 6756 C CG  . TYR B 1 366 ? 179.057 188.541 201.057 1.00 17.67 ? 350 TYR B CG  1 
ATOM 6757 C CD1 . TYR B 1 366 ? 178.677 188.959 199.788 1.00 17.67 ? 350 TYR B CD1 1 
ATOM 6758 C CD2 . TYR B 1 366 ? 180.390 188.222 201.268 1.00 17.67 ? 350 TYR B CD2 1 
ATOM 6759 C CE1 . TYR B 1 366 ? 179.604 189.083 198.772 1.00 17.67 ? 350 TYR B CE1 1 
ATOM 6760 C CE2 . TYR B 1 366 ? 181.322 188.343 200.260 1.00 17.67 ? 350 TYR B CE2 1 
ATOM 6761 C CZ  . TYR B 1 366 ? 180.925 188.773 199.013 1.00 17.67 ? 350 TYR B CZ  1 
ATOM 6762 O OH  . TYR B 1 366 ? 181.855 188.891 198.008 1.00 17.67 ? 350 TYR B OH  1 
ATOM 6763 N N   . TYR B 1 367 ? 178.227 190.750 204.916 1.00 17.30 ? 351 TYR B N   1 
ATOM 6764 C CA  . TYR B 1 367 ? 179.142 191.325 205.892 1.00 17.30 ? 351 TYR B CA  1 
ATOM 6765 C C   . TYR B 1 367 ? 179.973 190.223 206.538 1.00 17.30 ? 351 TYR B C   1 
ATOM 6766 O O   . TYR B 1 367 ? 179.429 189.323 207.183 1.00 17.30 ? 351 TYR B O   1 
ATOM 6767 C CB  . TYR B 1 367 ? 178.353 192.100 206.946 1.00 17.30 ? 351 TYR B CB  1 
ATOM 6768 C CG  . TYR B 1 367 ? 179.096 192.327 208.242 1.00 17.30 ? 351 TYR B CG  1 
ATOM 6769 C CD1 . TYR B 1 367 ? 180.187 193.183 208.301 1.00 17.30 ? 351 TYR B CD1 1 
ATOM 6770 C CD2 . TYR B 1 367 ? 178.702 191.688 209.410 1.00 17.30 ? 351 TYR B CD2 1 
ATOM 6771 C CE1 . TYR B 1 367 ? 180.866 193.393 209.485 1.00 17.30 ? 351 TYR B CE1 1 
ATOM 6772 C CE2 . TYR B 1 367 ? 179.375 191.891 210.598 1.00 17.30 ? 351 TYR B CE2 1 
ATOM 6773 C CZ  . TYR B 1 367 ? 180.457 192.744 210.630 1.00 17.30 ? 351 TYR B CZ  1 
ATOM 6774 O OH  . TYR B 1 367 ? 181.131 192.950 211.811 1.00 17.30 ? 351 TYR B OH  1 
ATOM 6775 N N   . ARG B 1 368 ? 181.290 190.294 206.368 1.00 17.32 ? 352 ARG B N   1 
ATOM 6776 C CA  . ARG B 1 368 ? 182.184 189.311 206.957 1.00 17.32 ? 352 ARG B CA  1 
ATOM 6777 C C   . ARG B 1 368 ? 182.426 189.636 208.430 1.00 17.32 ? 352 ARG B C   1 
ATOM 6778 O O   . ARG B 1 368 ? 181.734 190.457 209.038 1.00 17.32 ? 352 ARG B O   1 
ATOM 6779 C CB  . ARG B 1 368 ? 183.501 189.256 206.186 1.00 17.32 ? 352 ARG B CB  1 
ATOM 6780 C CG  . ARG B 1 368 ? 183.406 189.720 204.742 1.00 17.32 ? 352 ARG B CG  1 
ATOM 6781 C CD  . ARG B 1 368 ? 182.680 188.700 203.880 1.00 17.32 ? 352 ARG B CD  1 
ATOM 6782 N NE  . ARG B 1 368 ? 183.487 187.510 203.636 1.00 17.32 ? 352 ARG B NE  1 
ATOM 6783 C CZ  . ARG B 1 368 ? 184.525 187.461 202.812 1.00 17.32 ? 352 ARG B CZ  1 
ATOM 6784 N NH1 . ARG B 1 368 ? 184.911 188.521 202.121 1.00 17.32 ? 352 ARG B NH1 1 
ATOM 6785 N NH2 . ARG B 1 368 ? 185.190 186.317 202.675 1.00 17.32 ? 352 ARG B NH2 1 
ATOM 6786 N N   . VAL B 1 369 ? 183.418 188.971 209.018 1.00 17.43 ? 353 VAL B N   1 
ATOM 6787 C CA  . VAL B 1 369 ? 183.816 189.244 210.388 1.00 17.43 ? 353 VAL B CA  1 
ATOM 6788 C C   . VAL B 1 369 ? 185.223 189.828 210.481 1.00 17.43 ? 353 VAL B C   1 
ATOM 6789 O O   . VAL B 1 369 ? 185.428 190.799 211.219 1.00 17.43 ? 353 VAL B O   1 
ATOM 6790 C CB  . VAL B 1 369 ? 183.694 187.975 211.257 1.00 17.43 ? 353 VAL B CB  1 
ATOM 6791 C CG1 . VAL B 1 369 ? 184.242 188.227 212.653 1.00 17.43 ? 353 VAL B CG1 1 
ATOM 6792 C CG2 . VAL B 1 369 ? 182.244 187.527 211.328 1.00 17.43 ? 353 VAL B CG2 1 
ATOM 6793 N N   . GLY B 1 370 ? 186.191 189.278 209.752 1.00 18.19 ? 354 GLY B N   1 
ATOM 6794 C CA  . GLY B 1 370 ? 187.546 189.789 209.789 1.00 18.19 ? 354 GLY B CA  1 
ATOM 6795 C C   . GLY B 1 370 ? 187.881 190.706 208.631 1.00 18.19 ? 354 GLY B C   1 
ATOM 6796 O O   . GLY B 1 370 ? 188.967 191.292 208.591 1.00 18.19 ? 354 GLY B O   1 
ATOM 6797 N N   . ASP B 1 371 ? 186.958 190.842 207.682 1.00 18.13 ? 355 ASP B N   1 
ATOM 6798 C CA  . ASP B 1 371 ? 187.171 191.655 206.490 1.00 18.13 ? 355 ASP B CA  1 
ATOM 6799 C C   . ASP B 1 371 ? 186.229 192.843 206.385 1.00 18.13 ? 355 ASP B C   1 
ATOM 6800 O O   . ASP B 1 371 ? 186.665 193.931 206.002 1.00 18.13 ? 355 ASP B O   1 
ATOM 6801 C CB  . ASP B 1 371 ? 187.032 190.793 205.230 1.00 18.13 ? 355 ASP B CB  1 
ATOM 6802 C CG  . ASP B 1 371 ? 188.371 190.353 204.675 1.00 18.13 ? 355 ASP B CG  1 
ATOM 6803 O OD1 . ASP B 1 371 ? 189.411 190.745 205.245 1.00 18.13 ? 355 ASP B OD1 1 
ATOM 6804 O OD2 . ASP B 1 371 ? 188.385 189.616 203.667 1.00 18.13 ? 355 ASP B OD2 1 
ATOM 6805 N N   . ASN B 1 372 ? 184.947 192.659 206.713 1.00 20.55 ? 356 ASN B N   1 
ATOM 6806 C CA  . ASN B 1 372 ? 183.942 193.721 206.631 1.00 20.55 ? 356 ASN B CA  1 
ATOM 6807 C C   . ASN B 1 372 ? 183.864 194.296 205.217 1.00 20.55 ? 356 ASN B C   1 
ATOM 6808 O O   . ASN B 1 372 ? 184.086 195.487 204.991 1.00 20.55 ? 356 ASN B O   1 
ATOM 6809 C CB  . ASN B 1 372 ? 184.218 194.823 207.657 1.00 20.55 ? 356 ASN B CB  1 
ATOM 6810 C CG  . ASN B 1 372 ? 182.974 195.611 208.015 1.00 20.55 ? 356 ASN B CG  1 
ATOM 6811 O OD1 . ASN B 1 372 ? 182.174 195.959 207.147 1.00 20.55 ? 356 ASN B OD1 1 
ATOM 6812 N ND2 . ASN B 1 372 ? 182.810 195.905 209.299 1.00 20.55 ? 356 ASN B ND2 1 
ATOM 6813 N N   . VAL B 1 373 ? 183.546 193.434 204.258 1.00 19.49 ? 357 VAL B N   1 
ATOM 6814 C CA  . VAL B 1 373 ? 183.478 193.834 202.861 1.00 19.49 ? 357 VAL B CA  1 
ATOM 6815 C C   . VAL B 1 373 ? 182.023 194.083 202.480 1.00 19.49 ? 357 VAL B C   1 
ATOM 6816 O O   . VAL B 1 373 ? 181.090 193.664 203.169 1.00 19.49 ? 357 VAL B O   1 
ATOM 6817 C CB  . VAL B 1 373 ? 184.131 192.781 201.940 1.00 19.49 ? 357 VAL B CB  1 
ATOM 6818 C CG1 . VAL B 1 373 ? 183.139 191.681 201.587 1.00 19.49 ? 357 VAL B CG1 1 
ATOM 6819 C CG2 . VAL B 1 373 ? 184.703 193.436 200.691 1.00 19.49 ? 357 VAL B CG2 1 
ATOM 6820 N N   . TRP B 1 374 ? 181.829 194.792 201.368 1.00 24.41 ? 358 TRP B N   1 
ATOM 6821 C CA  . TRP B 1 374 ? 180.505 195.165 200.884 1.00 24.41 ? 358 TRP B CA  1 
ATOM 6822 C C   . TRP B 1 374 ? 180.295 194.733 199.436 1.00 24.41 ? 358 TRP B C   1 
ATOM 6823 O O   . TRP B 1 374 ? 179.554 195.376 198.691 1.00 24.41 ? 358 TRP B O   1 
ATOM 6824 C CB  . TRP B 1 374 ? 180.288 196.671 201.028 1.00 24.41 ? 358 TRP B CB  1 
ATOM 6825 C CG  . TRP B 1 374 ? 181.317 197.494 200.304 1.00 24.41 ? 358 TRP B CG  1 
ATOM 6826 C CD1 . TRP B 1 374 ? 181.290 197.874 198.993 1.00 24.41 ? 358 TRP B CD1 1 
ATOM 6827 C CD2 . TRP B 1 374 ? 182.528 198.033 200.851 1.00 24.41 ? 358 TRP B CD2 1 
ATOM 6828 N NE1 . TRP B 1 374 ? 182.405 198.617 198.691 1.00 24.41 ? 358 TRP B NE1 1 
ATOM 6829 C CE2 . TRP B 1 374 ? 183.181 198.729 199.815 1.00 24.41 ? 358 TRP B CE2 1 
ATOM 6830 C CE3 . TRP B 1 374 ? 183.121 197.996 202.116 1.00 24.41 ? 358 TRP B CE3 1 
ATOM 6831 C CZ2 . TRP B 1 374 ? 184.397 199.382 200.004 1.00 24.41 ? 358 TRP B CZ2 1 
ATOM 6832 C CZ3 . TRP B 1 374 ? 184.329 198.645 202.302 1.00 24.41 ? 358 TRP B CZ3 1 
ATOM 6833 C CH2 . TRP B 1 374 ? 184.953 199.328 201.252 1.00 24.41 ? 358 TRP B CH2 1 
ATOM 6834 N N   . THR B 1 375 ? 180.943 193.644 199.028 1.00 21.51 ? 359 THR B N   1 
ATOM 6835 C CA  . THR B 1 375 ? 180.910 193.227 197.632 1.00 21.51 ? 359 THR B CA  1 
ATOM 6836 C C   . THR B 1 375 ? 179.499 192.836 197.213 1.00 21.51 ? 359 THR B C   1 
ATOM 6837 O O   . THR B 1 375 ? 178.773 192.179 197.965 1.00 21.51 ? 359 THR B O   1 
ATOM 6838 C CB  . THR B 1 375 ? 181.865 192.056 197.405 1.00 21.51 ? 359 THR B CB  1 
ATOM 6839 O OG1 . THR B 1 375 ? 183.017 192.205 198.242 1.00 21.51 ? 359 THR B OG1 1 
ATOM 6840 C CG2 . THR B 1 375 ? 182.308 192.005 195.950 1.00 21.51 ? 359 THR B CG2 1 
ATOM 6841 N N   . GLU B 1 376 ? 179.112 193.249 196.010 1.00 22.20 ? 360 GLU B N   1 
ATOM 6842 C CA  . GLU B 1 376 ? 177.831 192.894 195.413 1.00 22.20 ? 360 GLU B CA  1 
ATOM 6843 C C   . GLU B 1 376 ? 178.083 191.999 194.208 1.00 22.20 ? 360 GLU B C   1 
ATOM 6844 O O   . GLU B 1 376 ? 178.772 192.403 193.265 1.00 22.20 ? 360 GLU B O   1 
ATOM 6845 C CB  . GLU B 1 376 ? 177.055 194.145 195.000 1.00 22.20 ? 360 GLU B CB  1 
ATOM 6846 C CG  . GLU B 1 376 ? 175.824 193.860 194.156 1.00 22.20 ? 360 GLU B CG  1 
ATOM 6847 C CD  . GLU B 1 376 ? 175.007 195.106 193.878 1.00 22.20 ? 360 GLU B CD  1 
ATOM 6848 O OE1 . GLU B 1 376 ? 175.414 196.198 194.328 1.00 22.20 ? 360 GLU B OE1 1 
ATOM 6849 O OE2 . GLU B 1 376 ? 173.966 194.996 193.199 1.00 22.20 ? 360 GLU B OE2 1 
ATOM 6850 N N   . THR B 1 377 ? 177.529 190.792 194.240 1.00 19.41 ? 361 THR B N   1 
ATOM 6851 C CA  . THR B 1 377 ? 177.658 189.843 193.148 1.00 19.41 ? 361 THR B CA  1 
ATOM 6852 C C   . THR B 1 377 ? 176.431 189.935 192.241 1.00 19.41 ? 361 THR B C   1 
ATOM 6853 O O   . THR B 1 377 ? 175.612 190.852 192.355 1.00 19.41 ? 361 THR B O   1 
ATOM 6854 C CB  . THR B 1 377 ? 177.864 188.428 193.692 1.00 19.41 ? 361 THR B CB  1 
ATOM 6855 O OG1 . THR B 1 377 ? 178.094 187.526 192.602 1.00 19.41 ? 361 THR B OG1 1 
ATOM 6856 C CG2 . THR B 1 377 ? 176.642 187.969 194.465 1.00 19.41 ? 361 THR B CG2 1 
ATOM 6857 N N   . THR B 1 378 ? 176.305 188.979 191.322 1.00 18.78 ? 362 THR B N   1 
ATOM 6858 C CA  . THR B 1 378 ? 175.217 188.997 190.353 1.00 18.78 ? 362 THR B CA  1 
ATOM 6859 C C   . THR B 1 378 ? 173.863 188.924 191.051 1.00 18.78 ? 362 THR B C   1 
ATOM 6860 O O   . THR B 1 378 ? 173.692 188.242 192.064 1.00 18.78 ? 362 THR B O   1 
ATOM 6861 C CB  . THR B 1 378 ? 175.358 187.833 189.371 1.00 18.78 ? 362 THR B CB  1 
ATOM 6862 O OG1 . THR B 1 378 ? 175.062 186.602 190.042 1.00 18.78 ? 362 THR B OG1 1 
ATOM 6863 C CG2 . THR B 1 378 ? 176.774 187.774 188.817 1.00 18.78 ? 362 THR B CG2 1 
ATOM 6864 N N   . GLN B 1 379 ? 172.893 189.643 190.491 1.00 26.88 ? 363 GLN B N   1 
ATOM 6865 C CA  . GLN B 1 379 ? 171.555 189.712 191.055 1.00 26.88 ? 363 GLN B CA  1 
ATOM 6866 C C   . GLN B 1 379 ? 170.780 188.431 190.749 1.00 26.88 ? 363 GLN B C   1 
ATOM 6867 O O   . GLN B 1 379 ? 171.273 187.513 190.087 1.00 26.88 ? 363 GLN B O   1 
ATOM 6868 C CB  . GLN B 1 379 ? 170.819 190.938 190.518 1.00 26.88 ? 363 GLN B CB  1 
ATOM 6869 C CG  . GLN B 1 379 ? 171.595 192.237 190.649 1.00 26.88 ? 363 GLN B CG  1 
ATOM 6870 C CD  . GLN B 1 379 ? 170.805 193.438 190.166 1.00 26.88 ? 363 GLN B CD  1 
ATOM 6871 O OE1 . GLN B 1 379 ? 169.676 193.304 189.695 1.00 26.88 ? 363 GLN B OE1 1 
ATOM 6872 N NE2 . GLN B 1 379 ? 171.397 194.621 190.281 1.00 26.88 ? 363 GLN B NE2 1 
ATOM 6873 N N   . LEU B 1 380 ? 169.545 188.372 191.236 1.00 26.16 ? 364 LEU B N   1 
ATOM 6874 C CA  . LEU B 1 380 ? 168.686 187.216 191.036 1.00 26.16 ? 364 LEU B CA  1 
ATOM 6875 C C   . LEU B 1 380 ? 168.026 187.300 189.660 1.00 26.16 ? 364 LEU B C   1 
ATOM 6876 O O   . LEU B 1 380 ? 168.247 188.243 188.896 1.00 26.16 ? 364 LEU B O   1 
ATOM 6877 C CB  . LEU B 1 380 ? 167.654 187.125 192.158 1.00 26.16 ? 364 LEU B CB  1 
ATOM 6878 C CG  . LEU B 1 380 ? 168.088 187.602 193.546 1.00 26.16 ? 364 LEU B CG  1 
ATOM 6879 C CD1 . LEU B 1 380 ? 166.909 187.593 194.506 1.00 26.16 ? 364 LEU B CD1 1 
ATOM 6880 C CD2 . LEU B 1 380 ? 169.222 186.742 194.084 1.00 26.16 ? 364 LEU B CD2 1 
ATOM 6881 N N   . GLU B 1 381 ? 167.201 186.307 189.332 1.00 21.87 ? 365 GLU B N   1 
ATOM 6882 C CA  . GLU B 1 381 ? 166.480 186.275 188.065 1.00 21.87 ? 365 GLU B CA  1 
ATOM 6883 C C   . GLU B 1 381 ? 165.050 186.780 188.184 1.00 21.87 ? 365 GLU B C   1 
ATOM 6884 O O   . GLU B 1 381 ? 164.556 187.449 187.272 1.00 21.87 ? 365 GLU B O   1 
ATOM 6885 C CB  . GLU B 1 381 ? 166.469 184.853 187.497 1.00 21.87 ? 365 GLU B CB  1 
ATOM 6886 C CG  . GLU B 1 381 ? 167.824 184.364 187.013 1.00 21.87 ? 365 GLU B CG  1 
ATOM 6887 C CD  . GLU B 1 381 ? 168.158 184.855 185.618 1.00 21.87 ? 365 GLU B CD  1 
ATOM 6888 O OE1 . GLU B 1 381 ? 167.305 185.527 185.001 1.00 21.87 ? 365 GLU B OE1 1 
ATOM 6889 O OE2 . GLU B 1 381 ? 169.275 184.568 185.138 1.00 21.87 ? 365 GLU B OE2 1 
ATOM 6890 N N   . VAL B 1 382 ? 164.373 186.474 189.288 1.00 21.47 ? 366 VAL B N   1 
ATOM 6891 C CA  . VAL B 1 382 ? 163.007 186.921 189.531 1.00 21.47 ? 366 VAL B CA  1 
ATOM 6892 C C   . VAL B 1 382 ? 162.981 187.669 190.855 1.00 21.47 ? 366 VAL B C   1 
ATOM 6893 O O   . VAL B 1 382 ? 163.473 187.162 191.869 1.00 21.47 ? 366 VAL B O   1 
ATOM 6894 C CB  . VAL B 1 382 ? 162.012 185.745 189.545 1.00 21.47 ? 366 VAL B CB  1 
ATOM 6895 C CG1 . VAL B 1 382 ? 160.645 186.208 190.027 1.00 21.47 ? 366 VAL B CG1 1 
ATOM 6896 C CG2 . VAL B 1 382 ? 161.912 185.126 188.160 1.00 21.47 ? 366 VAL B CG2 1 
ATOM 6897 N N   . ALA B 1 383 ? 162.413 188.871 190.840 1.00 19.50 ? 367 ALA B N   1 
ATOM 6898 C CA  . ALA B 1 383 ? 162.396 189.718 192.024 1.00 19.50 ? 367 ALA B CA  1 
ATOM 6899 C C   . ALA B 1 383 ? 161.528 189.105 193.117 1.00 19.50 ? 367 ALA B C   1 
ATOM 6900 O O   . ALA B 1 383 ? 160.462 188.547 192.840 1.00 19.50 ? 367 ALA B O   1 
ATOM 6901 C CB  . ALA B 1 383 ? 161.887 191.109 191.659 1.00 19.50 ? 367 ALA B CB  1 
ATOM 6902 N N   . VAL B 1 384 ? 161.989 189.211 194.362 1.00 23.38 ? 368 VAL B N   1 
ATOM 6903 C CA  . VAL B 1 384 ? 161.271 188.686 195.517 1.00 23.38 ? 368 VAL B CA  1 
ATOM 6904 C C   . VAL B 1 384 ? 161.679 189.488 196.747 1.00 23.38 ? 368 VAL B C   1 
ATOM 6905 O O   . VAL B 1 384 ? 162.828 189.926 196.863 1.00 23.38 ? 368 VAL B O   1 
ATOM 6906 C CB  . VAL B 1 384 ? 161.543 187.177 195.713 1.00 23.38 ? 368 VAL B CB  1 
ATOM 6907 C CG1 . VAL B 1 384 ? 163.019 186.923 195.989 1.00 23.38 ? 368 VAL B CG1 1 
ATOM 6908 C CG2 . VAL B 1 384 ? 160.674 186.607 196.824 1.00 23.38 ? 368 VAL B CG2 1 
ATOM 6909 N N   . SER B 1 385 ? 160.728 189.697 197.657 1.00 20.50 ? 369 SER B N   1 
ATOM 6910 C CA  . SER B 1 385 ? 160.985 190.419 198.894 1.00 20.50 ? 369 SER B CA  1 
ATOM 6911 C C   . SER B 1 385 ? 160.111 189.849 200.002 1.00 20.50 ? 369 SER B C   1 
ATOM 6912 O O   . SER B 1 385 ? 159.050 189.274 199.751 1.00 20.50 ? 369 SER B O   1 
ATOM 6913 C CB  . SER B 1 385 ? 160.727 191.922 198.738 1.00 20.50 ? 369 SER B CB  1 
ATOM 6914 O OG  . SER B 1 385 ? 160.972 192.608 199.954 1.00 20.50 ? 369 SER B OG  1 
ATOM 6915 N N   . GLY B 1 386 ? 160.571 190.026 201.239 1.00 21.81 ? 370 GLY B N   1 
ATOM 6916 C CA  . GLY B 1 386 ? 159.852 189.504 202.389 1.00 21.81 ? 370 GLY B CA  1 
ATOM 6917 C C   . GLY B 1 386 ? 159.743 187.997 202.414 1.00 21.81 ? 370 GLY B C   1 
ATOM 6918 O O   . GLY B 1 386 ? 158.741 187.460 202.897 1.00 21.81 ? 370 GLY B O   1 
ATOM 6919 N N   . ALA B 1 387 ? 160.752 187.298 201.907 1.00 16.92 ? 371 ALA B N   1 
ATOM 6920 C CA  . ALA B 1 387 ? 160.756 185.849 201.830 1.00 16.92 ? 371 ALA B CA  1 
ATOM 6921 C C   . ALA B 1 387 ? 161.514 185.261 203.018 1.00 16.92 ? 371 ALA B C   1 
ATOM 6922 O O   . ALA B 1 387 ? 161.864 185.960 203.974 1.00 16.92 ? 371 ALA B O   1 
ATOM 6923 C CB  . ALA B 1 387 ? 161.356 185.401 200.496 1.00 16.92 ? 371 ALA B CB  1 
ATOM 6924 N N   . ALA B 1 388 ? 161.762 183.955 202.965 1.00 15.56 ? 372 ALA B N   1 
ATOM 6925 C CA  . ALA B 1 388 ? 162.565 183.261 203.958 1.00 15.56 ? 372 ALA B CA  1 
ATOM 6926 C C   . ALA B 1 388 ? 163.693 182.523 203.254 1.00 15.56 ? 372 ALA B C   1 
ATOM 6927 O O   . ALA B 1 388 ? 163.562 182.116 202.096 1.00 15.56 ? 372 ALA B O   1 
ATOM 6928 C CB  . ALA B 1 388 ? 161.726 182.277 204.781 1.00 15.56 ? 372 ALA B CB  1 
ATOM 6929 N N   . GLY B 1 389 ? 164.806 182.360 203.957 1.00 12.57 ? 373 GLY B N   1 
ATOM 6930 C CA  . GLY B 1 389 ? 165.976 181.728 203.384 1.00 12.57 ? 373 GLY B CA  1 
ATOM 6931 C C   . GLY B 1 389 ? 166.542 180.660 204.295 1.00 12.57 ? 373 GLY B C   1 
ATOM 6932 O O   . GLY B 1 389 ? 166.490 180.763 205.521 1.00 12.57 ? 373 GLY B O   1 
ATOM 6933 N N   . ALA B 1 390 ? 167.088 179.620 203.669 1.00 10.19 ? 374 ALA B N   1 
ATOM 6934 C CA  . ALA B 1 390 ? 167.730 178.525 204.379 1.00 10.19 ? 374 ALA B CA  1 
ATOM 6935 C C   . ALA B 1 390 ? 168.939 178.060 203.584 1.00 10.19 ? 374 ALA B C   1 
ATOM 6936 O O   . ALA B 1 390 ? 168.857 177.882 202.365 1.00 10.19 ? 374 ALA B O   1 
ATOM 6937 C CB  . ALA B 1 390 ? 166.763 177.357 204.601 1.00 10.19 ? 374 ALA B CB  1 
ATOM 6938 N N   . ASN B 1 391 ? 170.055 177.864 204.277 1.00 14.04 ? 375 ASN B N   1 
ATOM 6939 C CA  . ASN B 1 391 ? 171.303 177.448 203.654 1.00 14.04 ? 375 ASN B CA  1 
ATOM 6940 C C   . ASN B 1 391 ? 171.445 175.935 203.729 1.00 14.04 ? 375 ASN B C   1 
ATOM 6941 O O   . ASN B 1 391 ? 171.069 175.314 204.727 1.00 14.04 ? 375 ASN B O   1 
ATOM 6942 C CB  . ASN B 1 391 ? 172.500 178.115 204.334 1.00 14.04 ? 375 ASN B CB  1 
ATOM 6943 C CG  . ASN B 1 391 ? 172.598 177.769 205.805 1.00 14.04 ? 375 ASN B CG  1 
ATOM 6944 O OD1 . ASN B 1 391 ? 171.920 178.365 206.641 1.00 14.04 ? 375 ASN B OD1 1 
ATOM 6945 N ND2 . ASN B 1 391 ? 173.444 176.799 206.129 1.00 14.04 ? 375 ASN B ND2 1 
ATOM 6946 N N   . LEU B 1 392 ? 171.991 175.344 202.668 1.00 16.22 ? 376 LEU B N   1 
ATOM 6947 C CA  . LEU B 1 392 ? 172.190 173.899 202.601 1.00 16.22 ? 376 LEU B CA  1 
ATOM 6948 C C   . LEU B 1 392 ? 173.504 173.629 201.882 1.00 16.22 ? 376 LEU B C   1 
ATOM 6949 O O   . LEU B 1 392 ? 173.651 173.989 200.711 1.00 16.22 ? 376 LEU B O   1 
ATOM 6950 C CB  . LEU B 1 392 ? 171.023 173.213 201.891 1.00 16.22 ? 376 LEU B CB  1 
ATOM 6951 C CG  . LEU B 1 392 ? 170.920 171.702 202.093 1.00 16.22 ? 376 LEU B CG  1 
ATOM 6952 C CD1 . LEU B 1 392 ? 170.991 171.358 203.572 1.00 16.22 ? 376 LEU B CD1 1 
ATOM 6953 C CD2 . LEU B 1 392 ? 169.636 171.174 201.481 1.00 16.22 ? 376 LEU B CD2 1 
ATOM 6954 N N   . ASN B 1 393 ? 174.453 173.016 202.598 1.00 15.42 ? 377 ASN B N   1 
ATOM 6955 C CA  . ASN B 1 393 ? 175.776 172.635 202.080 1.00 15.42 ? 377 ASN B CA  1 
ATOM 6956 C C   . ASN B 1 393 ? 176.435 173.757 201.275 1.00 15.42 ? 377 ASN B C   1 
ATOM 6957 O O   . ASN B 1 393 ? 177.242 173.518 200.374 1.00 15.42 ? 377 ASN B O   1 
ATOM 6958 C CB  . ASN B 1 393 ? 175.703 171.315 201.288 1.00 15.42 ? 377 ASN B CB  1 
ATOM 6959 C CG  . ASN B 1 393 ? 174.995 171.434 199.933 1.00 15.42 ? 377 ASN B CG  1 
ATOM 6960 O OD1 . ASN B 1 393 ? 175.123 172.420 199.210 1.00 15.42 ? 377 ASN B OD1 1 
ATOM 6961 N ND2 . ASN B 1 393 ? 174.235 170.400 199.593 1.00 15.42 ? 377 ASN B ND2 1 
ATOM 6962 N N   . GLY B 1 394 ? 176.120 174.996 201.633 1.00 16.58 ? 378 GLY B N   1 
ATOM 6963 C CA  . GLY B 1 394 ? 176.623 176.172 200.944 1.00 16.58 ? 378 GLY B CA  1 
ATOM 6964 C C   . GLY B 1 394 ? 175.630 176.794 199.985 1.00 16.58 ? 378 GLY B C   1 
ATOM 6965 O O   . GLY B 1 394 ? 175.588 178.017 199.839 1.00 16.58 ? 378 GLY B O   1 
ATOM 6966 N N   . ILE B 1 395 ? 174.820 175.964 199.324 1.00 15.23 ? 379 ILE B N   1 
ATOM 6967 C CA  . ILE B 1 395 ? 173.816 176.472 198.399 1.00 15.23 ? 379 ILE B CA  1 
ATOM 6968 C C   . ILE B 1 395 ? 172.701 177.154 199.181 1.00 15.23 ? 379 ILE B C   1 
ATOM 6969 O O   . ILE B 1 395 ? 172.207 176.628 200.189 1.00 15.23 ? 379 ILE B O   1 
ATOM 6970 C CB  . ILE B 1 395 ? 173.277 175.333 197.516 1.00 15.23 ? 379 ILE B CB  1 
ATOM 6971 C CG1 . ILE B 1 395 ? 174.118 175.209 196.245 1.00 15.23 ? 379 ILE B CG1 1 
ATOM 6972 C CG2 . ILE B 1 395 ? 171.827 175.572 197.148 1.00 15.23 ? 379 ILE B CG2 1 
ATOM 6973 C CD1 . ILE B 1 395 ? 173.714 174.056 195.357 1.00 15.23 ? 379 ILE B CD1 1 
ATOM 6974 N N   . ILE B 1 396 ? 172.305 178.338 198.723 1.00 15.95 ? 380 ILE B N   1 
ATOM 6975 C CA  . ILE B 1 396 ? 171.323 179.175 199.403 1.00 15.95 ? 380 ILE B CA  1 
ATOM 6976 C C   . ILE B 1 396 ? 170.012 179.103 198.633 1.00 15.95 ? 380 ILE B C   1 
ATOM 6977 O O   . ILE B 1 396 ? 169.984 179.347 197.421 1.00 15.95 ? 380 ILE B O   1 
ATOM 6978 C CB  . ILE B 1 396 ? 171.816 180.627 199.514 1.00 15.95 ? 380 ILE B CB  1 
ATOM 6979 C CG1 . ILE B 1 396 ? 172.924 180.742 200.559 1.00 15.95 ? 380 ILE B CG1 1 
ATOM 6980 C CG2 . ILE B 1 396 ? 170.664 181.558 199.855 1.00 15.95 ? 380 ILE B CG2 1 
ATOM 6981 C CD1 . ILE B 1 396 ? 173.297 182.166 200.877 1.00 15.95 ? 380 ILE B CD1 1 
ATOM 6982 N N   . TYR B 1 397 ? 168.930 178.773 199.333 1.00 14.44 ? 381 TYR B N   1 
ATOM 6983 C CA  . TYR B 1 397 ? 167.597 178.709 198.748 1.00 14.44 ? 381 TYR B CA  1 
ATOM 6984 C C   . TYR B 1 397 ? 166.756 179.888 199.214 1.00 14.44 ? 381 TYR B C   1 
ATOM 6985 O O   . TYR B 1 397 ? 166.669 180.161 200.416 1.00 14.44 ? 381 TYR B O   1 
ATOM 6986 C CB  . TYR B 1 397 ? 166.892 177.396 199.101 1.00 14.44 ? 381 TYR B CB  1 
ATOM 6987 C CG  . TYR B 1 397 ? 167.119 176.288 198.100 1.00 14.44 ? 381 TYR B CG  1 
ATOM 6988 C CD1 . TYR B 1 397 ? 168.297 175.558 198.088 1.00 14.44 ? 381 TYR B CD1 1 
ATOM 6989 C CD2 . TYR B 1 397 ? 166.148 175.981 197.158 1.00 14.44 ? 381 TYR B CD2 1 
ATOM 6990 C CE1 . TYR B 1 397 ? 168.497 174.547 197.166 1.00 14.44 ? 381 TYR B CE1 1 
ATOM 6991 C CE2 . TYR B 1 397 ? 166.340 174.977 196.235 1.00 14.44 ? 381 TYR B CE2 1 
ATOM 6992 C CZ  . TYR B 1 397 ? 167.515 174.263 196.242 1.00 14.44 ? 381 TYR B CZ  1 
ATOM 6993 O OH  . TYR B 1 397 ? 167.706 173.262 195.319 1.00 14.44 ? 381 TYR B OH  1 
ATOM 6994 N N   . LEU B 1 398 ? 166.145 180.584 198.257 1.00 16.82 ? 382 LEU B N   1 
ATOM 6995 C CA  . LEU B 1 398 ? 165.178 181.643 198.523 1.00 16.82 ? 382 LEU B CA  1 
ATOM 6996 C C   . LEU B 1 398 ? 163.799 181.112 198.152 1.00 16.82 ? 382 LEU B C   1 
ATOM 6997 O O   . LEU B 1 398 ? 163.534 180.824 196.980 1.00 16.82 ? 382 LEU B O   1 
ATOM 6998 C CB  . LEU B 1 398 ? 165.510 182.907 197.735 1.00 16.82 ? 382 LEU B CB  1 
ATOM 6999 C CG  . LEU B 1 398 ? 165.973 184.113 198.552 1.00 16.82 ? 382 LEU B CG  1 
ATOM 7000 C CD1 . LEU B 1 398 ? 166.448 185.222 197.631 1.00 16.82 ? 382 LEU B CD1 1 
ATOM 7001 C CD2 . LEU B 1 398 ? 164.857 184.604 199.459 1.00 16.82 ? 382 LEU B CD2 1 
ATOM 7002 N N   . LEU B 1 399 ? 162.926 180.982 199.146 1.00 15.72 ? 383 LEU B N   1 
ATOM 7003 C CA  . LEU B 1 399 ? 161.605 180.404 198.958 1.00 15.72 ? 383 LEU B CA  1 
ATOM 7004 C C   . LEU B 1 399 ? 160.531 181.344 199.489 1.00 15.72 ? 383 LEU B C   1 
ATOM 7005 O O   . LEU B 1 399 ? 160.768 182.109 200.429 1.00 15.72 ? 383 LEU B O   1 
ATOM 7006 C CB  . LEU B 1 399 ? 161.518 179.021 199.629 1.00 15.72 ? 383 LEU B CB  1 
ATOM 7007 C CG  . LEU B 1 399 ? 162.116 178.733 201.015 1.00 15.72 ? 383 LEU B CG  1 
ATOM 7008 C CD1 . LEU B 1 399 ? 161.557 179.610 202.128 1.00 15.72 ? 383 LEU B CD1 1 
ATOM 7009 C CD2 . LEU B 1 399 ? 161.964 177.259 201.364 1.00 15.72 ? 383 LEU B CD2 1 
ATOM 7010 N N   . GLY B 1 400 ? 159.357 181.297 198.864 1.00 20.22 ? 384 GLY B N   1 
ATOM 7011 C CA  . GLY B 1 400 ? 158.243 182.113 199.297 1.00 20.22 ? 384 GLY B CA  1 
ATOM 7012 C C   . GLY B 1 400 ? 158.431 183.586 198.981 1.00 20.22 ? 384 GLY B C   1 
ATOM 7013 O O   . GLY B 1 400 ? 159.142 183.977 198.049 1.00 20.22 ? 384 GLY B O   1 
ATOM 7014 N N   . GLY B 1 401 ? 157.771 184.412 199.781 1.00 19.63 ? 385 GLY B N   1 
ATOM 7015 C CA  . GLY B 1 401 ? 157.825 185.849 199.615 1.00 19.63 ? 385 GLY B CA  1 
ATOM 7016 C C   . GLY B 1 401 ? 156.672 186.379 198.789 1.00 19.63 ? 385 GLY B C   1 
ATOM 7017 O O   . GLY B 1 401 ? 155.688 185.691 198.501 1.00 19.63 ? 385 GLY B O   1 
ATOM 7018 N N   . GLU B 1 402 ? 156.811 187.644 198.400 1.00 21.28 ? 386 GLU B N   1 
ATOM 7019 C CA  . GLU B 1 402 ? 155.798 188.341 197.624 1.00 21.28 ? 386 GLU B CA  1 
ATOM 7020 C C   . GLU B 1 402 ? 156.457 189.094 196.479 1.00 21.28 ? 386 GLU B C   1 
ATOM 7021 O O   . GLU B 1 402 ? 157.595 189.558 196.591 1.00 21.28 ? 386 GLU B O   1 
ATOM 7022 C CB  . GLU B 1 402 ? 154.997 189.312 198.501 1.00 21.28 ? 386 GLU B CB  1 
ATOM 7023 C CG  . GLU B 1 402 ? 155.857 190.157 199.425 1.00 21.28 ? 386 GLU B CG  1 
ATOM 7024 C CD  . GLU B 1 402 ? 155.038 190.945 200.428 1.00 21.28 ? 386 GLU B CD  1 
ATOM 7025 O OE1 . GLU B 1 402 ? 153.862 190.586 200.649 1.00 21.28 ? 386 GLU B OE1 1 
ATOM 7026 O OE2 . GLU B 1 402 ? 155.570 191.921 200.996 1.00 21.28 ? 386 GLU B OE2 1 
ATOM 7027 N N   . GLU B 1 403 ? 155.728 189.207 195.371 1.00 25.11 ? 387 GLU B N   1 
ATOM 7028 C CA  . GLU B 1 403 ? 156.202 189.916 194.193 1.00 25.11 ? 387 GLU B CA  1 
ATOM 7029 C C   . GLU B 1 403 ? 155.066 190.748 193.620 1.00 25.11 ? 387 GLU B C   1 
ATOM 7030 O O   . GLU B 1 403 ? 153.936 190.267 193.496 1.00 25.11 ? 387 GLU B O   1 
ATOM 7031 C CB  . GLU B 1 403 ? 156.734 188.944 193.131 1.00 25.11 ? 387 GLU B CB  1 
ATOM 7032 C CG  . GLU B 1 403 ? 157.239 189.619 191.866 1.00 25.11 ? 387 GLU B CG  1 
ATOM 7033 C CD  . GLU B 1 403 ? 157.626 188.623 190.790 1.00 25.11 ? 387 GLU B CD  1 
ATOM 7034 O OE1 . GLU B 1 403 ? 157.209 187.450 190.887 1.00 25.11 ? 387 GLU B OE1 1 
ATOM 7035 O OE2 . GLU B 1 403 ? 158.346 189.014 189.848 1.00 25.11 ? 387 GLU B OE2 1 
ATOM 7036 N N   . ASN B 1 404 ? 155.371 191.993 193.273 1.00 20.12 ? 388 ASN B N   1 
ATOM 7037 C CA  . ASN B 1 404 ? 154.398 192.920 192.717 1.00 20.12 ? 388 ASN B CA  1 
ATOM 7038 C C   . ASN B 1 404 ? 154.648 193.111 191.226 1.00 20.12 ? 388 ASN B C   1 
ATOM 7039 O O   . ASN B 1 404 ? 155.663 192.675 190.677 1.00 20.12 ? 388 ASN B O   1 
ATOM 7040 C CB  . ASN B 1 404 ? 154.449 194.266 193.449 1.00 20.12 ? 388 ASN B CB  1 
ATOM 7041 C CG  . ASN B 1 404 ? 153.106 194.969 193.471 1.00 20.12 ? 388 ASN B CG  1 
ATOM 7042 O OD1 . ASN B 1 404 ? 152.787 195.753 192.577 1.00 20.12 ? 388 ASN B OD1 1 
ATOM 7043 N ND2 . ASN B 1 404 ? 152.310 194.692 194.497 1.00 20.12 ? 388 ASN B ND2 1 
ATOM 7044 N N   . ASP B 1 405 ? 153.700 193.777 190.572 1.00 21.38 ? 389 ASP B N   1 
ATOM 7045 C CA  . ASP B 1 405 ? 153.773 194.007 189.138 1.00 21.38 ? 389 ASP B CA  1 
ATOM 7046 C C   . ASP B 1 405 ? 153.228 195.394 188.829 1.00 21.38 ? 389 ASP B C   1 
ATOM 7047 O O   . ASP B 1 405 ? 152.680 196.078 189.697 1.00 21.38 ? 389 ASP B O   1 
ATOM 7048 C CB  . ASP B 1 405 ? 153.009 192.929 188.360 1.00 21.38 ? 389 ASP B CB  1 
ATOM 7049 C CG  . ASP B 1 405 ? 151.619 192.688 188.912 1.00 21.38 ? 389 ASP B CG  1 
ATOM 7050 O OD1 . ASP B 1 405 ? 151.490 192.497 190.140 1.00 21.38 ? 389 ASP B OD1 1 
ATOM 7051 O OD2 . ASP B 1 405 ? 150.654 192.687 188.119 1.00 21.38 ? 389 ASP B OD2 1 
ATOM 7052 N N   . LEU B 1 406 ? 153.388 195.804 187.569 1.00 24.44 ? 390 LEU B N   1 
ATOM 7053 C CA  . LEU B 1 406 ? 152.934 197.119 187.131 1.00 24.44 ? 390 LEU B CA  1 
ATOM 7054 C C   . LEU B 1 406 ? 151.417 197.258 187.138 1.00 24.44 ? 390 LEU B C   1 
ATOM 7055 O O   . LEU B 1 406 ? 150.918 198.383 187.030 1.00 24.44 ? 390 LEU B O   1 
ATOM 7056 C CB  . LEU B 1 406 ? 153.472 197.417 185.730 1.00 24.44 ? 390 LEU B CB  1 
ATOM 7057 C CG  . LEU B 1 406 ? 154.990 197.328 185.560 1.00 24.44 ? 390 LEU B CG  1 
ATOM 7058 C CD1 . LEU B 1 406 ? 155.386 197.598 184.117 1.00 24.44 ? 390 LEU B CD1 1 
ATOM 7059 C CD2 . LEU B 1 406 ? 155.694 198.292 186.503 1.00 24.44 ? 390 LEU B CD2 1 
ATOM 7060 N N   . ASP B 1 407 ? 150.679 196.157 187.261 1.00 26.33 ? 391 ASP B N   1 
ATOM 7061 C CA  . ASP B 1 407 ? 149.223 196.201 187.306 1.00 26.33 ? 391 ASP B CA  1 
ATOM 7062 C C   . ASP B 1 407 ? 148.683 196.493 188.700 1.00 26.33 ? 391 ASP B C   1 
ATOM 7063 O O   . ASP B 1 407 ? 147.460 196.559 188.868 1.00 26.33 ? 391 ASP B O   1 
ATOM 7064 C CB  . ASP B 1 407 ? 148.643 194.879 186.793 1.00 26.33 ? 391 ASP B CB  1 
ATOM 7065 C CG  . ASP B 1 407 ? 147.237 195.033 186.245 1.00 26.33 ? 391 ASP B CG  1 
ATOM 7066 O OD1 . ASP B 1 407 ? 146.835 196.178 185.946 1.00 26.33 ? 391 ASP B OD1 1 
ATOM 7067 O OD2 . ASP B 1 407 ? 146.533 194.010 186.114 1.00 26.33 ? 391 ASP B OD2 1 
ATOM 7068 N N   . PHE B 1 408 ? 149.560 196.664 189.693 1.00 26.22 ? 392 PHE B N   1 
ATOM 7069 C CA  . PHE B 1 408 ? 149.163 196.936 191.076 1.00 26.22 ? 392 PHE B CA  1 
ATOM 7070 C C   . PHE B 1 408 ? 148.279 195.815 191.623 1.00 26.22 ? 392 PHE B C   1 
ATOM 7071 O O   . PHE B 1 408 ? 147.187 196.047 192.147 1.00 26.22 ? 392 PHE B O   1 
ATOM 7072 C CB  . PHE B 1 408 ? 148.468 198.296 191.195 1.00 26.22 ? 392 PHE B CB  1 
ATOM 7073 C CG  . PHE B 1 408 ? 149.364 199.462 190.893 1.00 26.22 ? 392 PHE B CG  1 
ATOM 7074 C CD1 . PHE B 1 408 ? 150.244 199.943 191.849 1.00 26.22 ? 392 PHE B CD1 1 
ATOM 7075 C CD2 . PHE B 1 408 ? 149.327 200.078 189.653 1.00 26.22 ? 392 PHE B CD2 1 
ATOM 7076 C CE1 . PHE B 1 408 ? 151.070 201.017 191.573 1.00 26.22 ? 392 PHE B CE1 1 
ATOM 7077 C CE2 . PHE B 1 408 ? 150.150 201.152 189.372 1.00 26.22 ? 392 PHE B CE2 1 
ATOM 7078 C CZ  . PHE B 1 408 ? 151.023 201.622 190.333 1.00 26.22 ? 392 PHE B CZ  1 
ATOM 7079 N N   . PHE B 1 409 ? 148.767 194.584 191.495 1.00 24.64 ? 393 PHE B N   1 
ATOM 7080 C CA  . PHE B 1 409 ? 148.065 193.398 191.964 1.00 24.64 ? 393 PHE B CA  1 
ATOM 7081 C C   . PHE B 1 409 ? 148.913 192.705 193.021 1.00 24.64 ? 393 PHE B C   1 
ATOM 7082 O O   . PHE B 1 409 ? 150.104 192.459 192.803 1.00 24.64 ? 393 PHE B O   1 
ATOM 7083 C CB  . PHE B 1 409 ? 147.770 192.439 190.806 1.00 24.64 ? 393 PHE B CB  1 
ATOM 7084 C CG  . PHE B 1 409 ? 146.764 191.372 191.139 1.00 24.64 ? 393 PHE B CG  1 
ATOM 7085 C CD1 . PHE B 1 409 ? 145.860 191.549 192.174 1.00 24.64 ? 393 PHE B CD1 1 
ATOM 7086 C CD2 . PHE B 1 409 ? 146.725 190.191 190.417 1.00 24.64 ? 393 PHE B CD2 1 
ATOM 7087 C CE1 . PHE B 1 409 ? 144.936 190.568 192.482 1.00 24.64 ? 393 PHE B CE1 1 
ATOM 7088 C CE2 . PHE B 1 409 ? 145.803 189.206 190.720 1.00 24.64 ? 393 PHE B CE2 1 
ATOM 7089 C CZ  . PHE B 1 409 ? 144.908 189.395 191.753 1.00 24.64 ? 393 PHE B CZ  1 
ATOM 7090 N N   . THR B 1 410 ? 148.299 192.394 194.163 1.00 23.26 ? 394 THR B N   1 
ATOM 7091 C CA  . THR B 1 410 ? 148.990 191.708 195.256 1.00 23.26 ? 394 THR B CA  1 
ATOM 7092 C C   . THR B 1 410 ? 148.957 190.208 194.978 1.00 23.26 ? 394 THR B C   1 
ATOM 7093 O O   . THR B 1 410 ? 148.199 189.442 195.576 1.00 23.26 ? 394 THR B O   1 
ATOM 7094 C CB  . THR B 1 410 ? 148.353 192.050 196.597 1.00 23.26 ? 394 THR B CB  1 
ATOM 7095 O OG1 . THR B 1 410 ? 146.948 191.771 196.545 1.00 23.26 ? 394 THR B OG1 1 
ATOM 7096 C CG2 . THR B 1 410 ? 148.560 193.521 196.925 1.00 23.26 ? 394 THR B CG2 1 
ATOM 7097 N N   . LYS B 1 411 ? 149.806 189.789 194.042 1.00 20.41 ? 395 LYS B N   1 
ATOM 7098 C CA  . LYS B 1 411 ? 149.862 188.393 193.630 1.00 20.41 ? 395 LYS B CA  1 
ATOM 7099 C C   . LYS B 1 411 ? 150.889 187.648 194.470 1.00 20.41 ? 395 LYS B C   1 
ATOM 7100 O O   . LYS B 1 411 ? 152.073 188.012 194.443 1.00 20.41 ? 395 LYS B O   1 
ATOM 7101 C CB  . LYS B 1 411 ? 150.217 188.283 192.157 1.00 20.41 ? 395 LYS B CB  1 
ATOM 7102 C CG  . LYS B 1 411 ? 149.897 186.932 191.540 1.00 20.41 ? 395 LYS B CG  1 
ATOM 7103 C CD  . LYS B 1 411 ? 148.408 186.637 191.605 1.00 20.41 ? 395 LYS B CD  1 
ATOM 7104 C CE  . LYS B 1 411 ? 148.086 185.287 190.985 1.00 20.41 ? 395 LYS B CE  1 
ATOM 7105 N NZ  . LYS B 1 411 ? 146.620 185.035 190.935 1.00 20.41 ? 395 LYS B NZ  1 
ATOM 7106 N N   . PRO B 1 412 ? 150.494 186.628 195.230 1.00 19.42 ? 396 PRO B N   1 
ATOM 7107 C CA  . PRO B 1 412 ? 151.479 185.848 195.987 1.00 19.42 ? 396 PRO B CA  1 
ATOM 7108 C C   . PRO B 1 412 ? 152.462 185.151 195.057 1.00 19.42 ? 396 PRO B C   1 
ATOM 7109 O O   . PRO B 1 412 ? 152.113 184.738 193.949 1.00 19.42 ? 396 PRO B O   1 
ATOM 7110 C CB  . PRO B 1 412 ? 150.619 184.839 196.757 1.00 19.42 ? 396 PRO B CB  1 
ATOM 7111 C CG  . PRO B 1 412 ? 149.257 185.453 196.804 1.00 19.42 ? 396 PRO B CG  1 
ATOM 7112 C CD  . PRO B 1 412 ? 149.114 186.201 195.514 1.00 19.42 ? 396 PRO B CD  1 
ATOM 7113 N N   . SER B 1 413 ? 153.702 185.024 195.519 1.00 19.54 ? 397 SER B N   1 
ATOM 7114 C CA  . SER B 1 413 ? 154.771 184.416 194.738 1.00 19.54 ? 397 SER B CA  1 
ATOM 7115 C C   . SER B 1 413 ? 155.030 182.999 195.232 1.00 19.54 ? 397 SER B C   1 
ATOM 7116 O O   . SER B 1 413 ? 155.286 182.788 196.422 1.00 19.54 ? 397 SER B O   1 
ATOM 7117 C CB  . SER B 1 413 ? 156.050 185.248 194.826 1.00 19.54 ? 397 SER B CB  1 
ATOM 7118 O OG  . SER B 1 413 ? 156.790 184.924 195.989 1.00 19.54 ? 397 SER B OG  1 
ATOM 7119 N N   . ARG B 1 414 ? 154.970 182.035 194.314 1.00 15.70 ? 398 ARG B N   1 
ATOM 7120 C CA  . ARG B 1 414 ? 155.201 180.629 194.623 1.00 15.70 ? 398 ARG B CA  1 
ATOM 7121 C C   . ARG B 1 414 ? 156.489 180.125 193.981 1.00 15.70 ? 398 ARG B C   1 
ATOM 7122 O O   . ARG B 1 414 ? 156.653 178.923 193.764 1.00 15.70 ? 398 ARG B O   1 
ATOM 7123 C CB  . ARG B 1 414 ? 154.017 179.773 194.175 1.00 15.70 ? 398 ARG B CB  1 
ATOM 7124 C CG  . ARG B 1 414 ? 152.672 180.469 194.258 1.00 15.70 ? 398 ARG B CG  1 
ATOM 7125 C CD  . ARG B 1 414 ? 151.571 179.601 193.673 1.00 15.70 ? 398 ARG B CD  1 
ATOM 7126 N NE  . ARG B 1 414 ? 150.951 178.750 194.681 1.00 15.70 ? 398 ARG B NE  1 
ATOM 7127 C CZ  . ARG B 1 414 ? 149.703 178.885 195.110 1.00 15.70 ? 398 ARG B CZ  1 
ATOM 7128 N NH1 . ARG B 1 414 ? 148.909 179.832 194.639 1.00 15.70 ? 398 ARG B NH1 1 
ATOM 7129 N NH2 . ARG B 1 414 ? 149.241 178.047 196.034 1.00 15.70 ? 398 ARG B NH2 1 
ATOM 7130 N N   . LEU B 1 415 ? 157.409 181.031 193.671 1.00 16.72 ? 399 LEU B N   1 
ATOM 7131 C CA  . LEU B 1 415 ? 158.633 180.690 192.960 1.00 16.72 ? 399 LEU B CA  1 
ATOM 7132 C C   . LEU B 1 415 ? 159.772 180.493 193.951 1.00 16.72 ? 399 LEU B C   1 
ATOM 7133 O O   . LEU B 1 415 ? 159.913 181.263 194.906 1.00 16.72 ? 399 LEU B O   1 
ATOM 7134 C CB  . LEU B 1 415 ? 158.993 181.778 191.947 1.00 16.72 ? 399 LEU B CB  1 
ATOM 7135 C CG  . LEU B 1 415 ? 160.095 181.432 190.945 1.00 16.72 ? 399 LEU B CG  1 
ATOM 7136 C CD1 . LEU B 1 415 ? 159.914 180.021 190.409 1.00 16.72 ? 399 LEU B CD1 1 
ATOM 7137 C CD2 . LEU B 1 415 ? 160.102 182.436 189.808 1.00 16.72 ? 399 LEU B CD2 1 
ATOM 7138 N N   . ILE B 1 416 ? 160.581 179.463 193.714 1.00 16.30 ? 400 ILE B N   1 
ATOM 7139 C CA  . ILE B 1 416 ? 161.727 179.132 194.551 1.00 16.30 ? 400 ILE B CA  1 
ATOM 7140 C C   . ILE B 1 416 ? 162.996 179.509 193.797 1.00 16.30 ? 400 ILE B C   1 
ATOM 7141 O O   . ILE B 1 416 ? 163.098 179.284 192.585 1.00 16.30 ? 400 ILE B O   1 
ATOM 7142 C CB  . ILE B 1 416 ? 161.724 177.644 194.959 1.00 16.30 ? 400 ILE B CB  1 
ATOM 7143 C CG1 . ILE B 1 416 ? 162.570 177.421 196.214 1.00 16.30 ? 400 ILE B CG1 1 
ATOM 7144 C CG2 . ILE B 1 416 ? 162.161 176.736 193.821 1.00 16.30 ? 400 ILE B CG2 1 
ATOM 7145 C CD1 . ILE B 1 416 ? 161.939 176.482 197.212 1.00 16.30 ? 400 ILE B CD1 1 
ATOM 7146 N N   . GLN B 1 417 ? 163.935 180.136 194.500 1.00 18.67 ? 401 GLN B N   1 
ATOM 7147 C CA  . GLN B 1 417 ? 165.192 180.577 193.917 1.00 18.67 ? 401 GLN B CA  1 
ATOM 7148 C C   . GLN B 1 417 ? 166.357 179.904 194.627 1.00 18.67 ? 401 GLN B C   1 
ATOM 7149 O O   . GLN B 1 417 ? 166.337 179.734 195.850 1.00 18.67 ? 401 GLN B O   1 
ATOM 7150 C CB  . GLN B 1 417 ? 165.342 182.100 194.002 1.00 18.67 ? 401 GLN B CB  1 
ATOM 7151 C CG  . GLN B 1 417 ? 164.319 182.878 193.188 1.00 18.67 ? 401 GLN B CG  1 
ATOM 7152 C CD  . GLN B 1 417 ? 164.611 182.871 191.699 1.00 18.67 ? 401 GLN B CD  1 
ATOM 7153 O OE1 . GLN B 1 417 ? 163.790 183.313 190.896 1.00 18.67 ? 401 GLN B OE1 1 
ATOM 7154 N NE2 . GLN B 1 417 ? 165.787 182.381 191.323 1.00 18.67 ? 401 GLN B NE2 1 
ATOM 7155 N N   . CYS B 1 418 ? 167.371 179.526 193.855 1.00 18.61 ? 402 CYS B N   1 
ATOM 7156 C CA  . CYS B 1 418 ? 168.586 178.925 194.387 1.00 18.61 ? 402 CYS B CA  1 
ATOM 7157 C C   . CYS B 1 418 ? 169.758 179.863 194.137 1.00 18.61 ? 402 CYS B C   1 
ATOM 7158 O O   . CYS B 1 418 ? 169.847 180.486 193.074 1.00 18.61 ? 402 CYS B O   1 
ATOM 7159 C CB  . CYS B 1 418 ? 168.842 177.552 193.756 1.00 18.61 ? 402 CYS B CB  1 
ATOM 7160 S SG  . CYS B 1 418 ? 169.886 177.545 192.278 1.00 18.61 ? 402 CYS B SG  1 
ATOM 7161 N N   . PHE B 1 419 ? 170.636 179.983 195.128 1.00 17.68 ? 403 PHE B N   1 
ATOM 7162 C CA  . PHE B 1 419 ? 171.821 180.836 195.050 1.00 17.68 ? 403 PHE B CA  1 
ATOM 7163 C C   . PHE B 1 419 ? 173.037 179.920 195.123 1.00 17.68 ? 403 PHE B C   1 
ATOM 7164 O O   . PHE B 1 419 ? 173.407 179.454 196.205 1.00 17.68 ? 403 PHE B O   1 
ATOM 7165 C CB  . PHE B 1 419 ? 171.819 181.877 196.168 1.00 17.68 ? 403 PHE B CB  1 
ATOM 7166 C CG  . PHE B 1 419 ? 172.987 182.824 196.128 1.00 17.68 ? 403 PHE B CG  1 
ATOM 7167 C CD1 . PHE B 1 419 ? 174.175 182.515 196.770 1.00 17.68 ? 403 PHE B CD1 1 
ATOM 7168 C CD2 . PHE B 1 419 ? 172.890 184.034 195.462 1.00 17.68 ? 403 PHE B CD2 1 
ATOM 7169 C CE1 . PHE B 1 419 ? 175.246 183.388 196.738 1.00 17.68 ? 403 PHE B CE1 1 
ATOM 7170 C CE2 . PHE B 1 419 ? 173.958 184.911 195.426 1.00 17.68 ? 403 PHE B CE2 1 
ATOM 7171 C CZ  . PHE B 1 419 ? 175.137 184.587 196.065 1.00 17.68 ? 403 PHE B CZ  1 
ATOM 7172 N N   . ASP B 1 420 ? 173.653 179.660 193.973 1.00 19.83 ? 404 ASP B N   1 
ATOM 7173 C CA  . ASP B 1 420 ? 174.774 178.735 193.915 1.00 19.83 ? 404 ASP B CA  1 
ATOM 7174 C C   . ASP B 1 420 ? 175.966 179.276 194.696 1.00 19.83 ? 404 ASP B C   1 
ATOM 7175 O O   . ASP B 1 420 ? 176.175 180.487 194.803 1.00 19.83 ? 404 ASP B O   1 
ATOM 7176 C CB  . ASP B 1 420 ? 175.176 178.469 192.465 1.00 19.83 ? 404 ASP B CB  1 
ATOM 7177 C CG  . ASP B 1 420 ? 174.915 177.036 192.044 1.00 19.83 ? 404 ASP B CG  1 
ATOM 7178 O OD1 . ASP B 1 420 ? 174.242 176.306 192.801 1.00 19.83 ? 404 ASP B OD1 1 
ATOM 7179 O OD2 . ASP B 1 420 ? 175.384 176.640 190.956 1.00 19.83 ? 404 ASP B OD2 1 
ATOM 7180 N N   . THR B 1 421 ? 176.747 178.355 195.253 1.00 22.59 ? 405 THR B N   1 
ATOM 7181 C CA  . THR B 1 421 ? 177.919 178.690 196.047 1.00 22.59 ? 405 THR B CA  1 
ATOM 7182 C C   . THR B 1 421 ? 179.224 178.514 195.283 1.00 22.59 ? 405 THR B C   1 
ATOM 7183 O O   . THR B 1 421 ? 180.278 178.922 195.782 1.00 22.59 ? 405 THR B O   1 
ATOM 7184 C CB  . THR B 1 421 ? 177.953 177.836 197.319 1.00 22.59 ? 405 THR B CB  1 
ATOM 7185 O OG1 . THR B 1 421 ? 178.922 178.367 198.229 1.00 22.59 ? 405 THR B OG1 1 
ATOM 7186 C CG2 . THR B 1 421 ? 178.313 176.396 196.985 1.00 22.59 ? 405 THR B CG2 1 
ATOM 7187 N N   . GLU B 1 422 ? 179.183 177.923 194.091 1.00 24.35 ? 406 GLU B N   1 
ATOM 7188 C CA  . GLU B 1 422 ? 180.384 177.658 193.309 1.00 24.35 ? 406 GLU B CA  1 
ATOM 7189 C C   . GLU B 1 422 ? 180.381 178.370 191.967 1.00 24.35 ? 406 GLU B C   1 
ATOM 7190 O O   . GLU B 1 422 ? 181.383 178.996 191.601 1.00 24.35 ? 406 GLU B O   1 
ATOM 7191 C CB  . GLU B 1 422 ? 180.548 176.143 193.101 1.00 24.35 ? 406 GLU B CB  1 
ATOM 7192 C CG  . GLU B 1 422 ? 181.991 175.662 193.123 1.00 24.35 ? 406 GLU B CG  1 
ATOM 7193 C CD  . GLU B 1 422 ? 182.627 175.658 191.747 1.00 24.35 ? 406 GLU B CD  1 
ATOM 7194 O OE1 . GLU B 1 422 ? 181.881 175.643 190.745 1.00 24.35 ? 406 GLU B OE1 1 
ATOM 7195 O OE2 . GLU B 1 422 ? 183.873 175.668 191.666 1.00 24.35 ? 406 GLU B OE2 1 
ATOM 7196 N N   . THR B 1 423 ? 179.281 178.295 191.217 1.00 23.33 ? 407 THR B N   1 
ATOM 7197 C CA  . THR B 1 423 ? 179.226 178.870 189.880 1.00 23.33 ? 407 THR B CA  1 
ATOM 7198 C C   . THR B 1 423 ? 178.463 180.185 189.808 1.00 23.33 ? 407 THR B C   1 
ATOM 7199 O O   . THR B 1 423 ? 178.594 180.898 188.807 1.00 23.33 ? 407 THR B O   1 
ATOM 7200 C CB  . THR B 1 423 ? 178.588 177.876 188.900 1.00 23.33 ? 407 THR B CB  1 
ATOM 7201 O OG1 . THR B 1 423 ? 177.314 177.455 189.404 1.00 23.33 ? 407 THR B OG1 1 
ATOM 7202 C CG2 . THR B 1 423 ? 179.483 176.660 188.716 1.00 23.33 ? 407 THR B CG2 1 
ATOM 7203 N N   . ASP B 1 424 ? 177.682 180.522 190.834 1.00 23.95 ? 408 ASP B N   1 
ATOM 7204 C CA  . ASP B 1 424 ? 176.847 181.723 190.844 1.00 23.95 ? 408 ASP B CA  1 
ATOM 7205 C C   . ASP B 1 424 ? 175.930 181.749 189.620 1.00 23.95 ? 408 ASP B C   1 
ATOM 7206 O O   . ASP B 1 424 ? 176.015 182.619 188.752 1.00 23.95 ? 408 ASP B O   1 
ATOM 7207 C CB  . ASP B 1 424 ? 177.704 182.989 190.926 1.00 23.95 ? 408 ASP B CB  1 
ATOM 7208 C CG  . ASP B 1 424 ? 178.546 183.041 192.185 1.00 23.95 ? 408 ASP B CG  1 
ATOM 7209 O OD1 . ASP B 1 424 ? 179.414 182.160 192.359 1.00 23.95 ? 408 ASP B OD1 1 
ATOM 7210 O OD2 . ASP B 1 424 ? 178.339 183.963 193.002 1.00 23.95 ? 408 ASP B OD2 1 
ATOM 7211 N N   . LYS B 1 425 ? 175.040 180.762 189.571 1.00 23.70 ? 409 LYS B N   1 
ATOM 7212 C CA  . LYS B 1 425 ? 174.157 180.514 188.436 1.00 23.70 ? 409 LYS B CA  1 
ATOM 7213 C C   . LYS B 1 425 ? 172.706 180.468 188.902 1.00 23.70 ? 409 LYS B C   1 
ATOM 7214 O O   . LYS B 1 425 ? 171.969 179.515 188.641 1.00 23.70 ? 409 LYS B O   1 
ATOM 7215 C CB  . LYS B 1 425 ? 174.550 179.225 187.717 1.00 23.70 ? 409 LYS B CB  1 
ATOM 7216 C CG  . LYS B 1 425 ? 173.972 179.085 186.314 1.00 23.70 ? 409 LYS B CG  1 
ATOM 7217 C CD  . LYS B 1 425 ? 174.386 180.244 185.422 1.00 23.70 ? 409 LYS B CD  1 
ATOM 7218 C CE  . LYS B 1 425 ? 175.888 180.251 185.184 1.00 23.70 ? 409 LYS B CE  1 
ATOM 7219 N NZ  . LYS B 1 425 ? 176.373 178.940 184.670 1.00 23.70 ? 409 LYS B NZ  1 
ATOM 7220 N N   . CYS B 1 426 ? 172.297 181.498 189.643 1.00 23.85 ? 410 CYS B N   1 
ATOM 7221 C CA  . CYS B 1 426 ? 170.942 181.562 190.176 1.00 23.85 ? 410 CYS B CA  1 
ATOM 7222 C C   . CYS B 1 426 ? 169.915 181.412 189.060 1.00 23.85 ? 410 CYS B C   1 
ATOM 7223 O O   . CYS B 1 426 ? 169.992 182.089 188.031 1.00 23.85 ? 410 CYS B O   1 
ATOM 7224 C CB  . CYS B 1 426 ? 170.729 182.886 190.908 1.00 23.85 ? 410 CYS B CB  1 
ATOM 7225 S SG  . CYS B 1 426 ? 171.865 183.169 192.280 1.00 23.85 ? 410 CYS B SG  1 
ATOM 7226 N N   . HIS B 1 427 ? 168.951 180.519 189.271 1.00 22.37 ? 411 HIS B N   1 
ATOM 7227 C CA  . HIS B 1 427 ? 167.958 180.209 188.255 1.00 22.37 ? 411 HIS B CA  1 
ATOM 7228 C C   . HIS B 1 427 ? 166.703 179.673 188.926 1.00 22.37 ? 411 HIS B C   1 
ATOM 7229 O O   . HIS B 1 427 ? 166.747 179.140 190.038 1.00 22.37 ? 411 HIS B O   1 
ATOM 7230 C CB  . HIS B 1 427 ? 168.504 179.201 187.235 1.00 22.37 ? 411 HIS B CB  1 
ATOM 7231 C CG  . HIS B 1 427 ? 168.321 177.771 187.639 1.00 22.37 ? 411 HIS B CG  1 
ATOM 7232 N ND1 . HIS B 1 427 ? 167.304 176.981 187.148 1.00 22.37 ? 411 HIS B ND1 1 
ATOM 7233 C CD2 . HIS B 1 427 ? 169.028 176.988 188.488 1.00 22.37 ? 411 HIS B CD2 1 
ATOM 7234 C CE1 . HIS B 1 427 ? 167.394 175.773 187.676 1.00 22.37 ? 411 HIS B CE1 1 
ATOM 7235 N NE2 . HIS B 1 427 ? 168.431 175.752 188.494 1.00 22.37 ? 411 HIS B NE2 1 
ATOM 7236 N N   . VAL B 1 428 ? 165.576 179.824 188.232 1.00 22.77 ? 412 VAL B N   1 
ATOM 7237 C CA  . VAL B 1 428 ? 164.304 179.347 188.756 1.00 22.77 ? 412 VAL B CA  1 
ATOM 7238 C C   . VAL B 1 428 ? 164.180 177.844 188.528 1.00 22.77 ? 412 VAL B C   1 
ATOM 7239 O O   . VAL B 1 428 ? 164.802 177.265 187.633 1.00 22.77 ? 412 VAL B O   1 
ATOM 7240 C CB  . VAL B 1 428 ? 163.125 180.109 188.122 1.00 22.77 ? 412 VAL B CB  1 
ATOM 7241 C CG1 . VAL B 1 428 ? 163.371 181.606 188.183 1.00 22.77 ? 412 VAL B CG1 1 
ATOM 7242 C CG2 . VAL B 1 428 ? 162.910 179.660 186.685 1.00 22.77 ? 412 VAL B CG2 1 
ATOM 7243 N N   . LYS B 1 429 ? 163.359 177.203 189.358 1.00 21.39 ? 413 LYS B N   1 
ATOM 7244 C CA  . LYS B 1 429 ? 163.148 175.771 189.249 1.00 21.39 ? 413 LYS B CA  1 
ATOM 7245 C C   . LYS B 1 429 ? 161.853 175.475 188.501 1.00 21.39 ? 413 LYS B C   1 
ATOM 7246 O O   . LYS B 1 429 ? 160.901 176.259 188.577 1.00 21.39 ? 413 LYS B O   1 
ATOM 7247 C CB  . LYS B 1 429 ? 163.098 175.115 190.633 1.00 21.39 ? 413 LYS B CB  1 
ATOM 7248 C CG  . LYS B 1 429 ? 164.369 175.288 191.452 1.00 21.39 ? 413 LYS B CG  1 
ATOM 7249 C CD  . LYS B 1 429 ? 165.593 174.801 190.697 1.00 21.39 ? 413 LYS B CD  1 
ATOM 7250 C CE  . LYS B 1 429 ? 166.829 174.829 191.581 1.00 21.39 ? 413 LYS B CE  1 
ATOM 7251 N NZ  . LYS B 1 429 ? 166.625 174.069 192.845 1.00 21.39 ? 413 LYS B NZ  1 
ATOM 7252 N N   . PRO B 1 430 ? 161.785 174.358 187.772 1.00 22.47 ? 414 PRO B N   1 
ATOM 7253 C CA  . PRO B 1 430 ? 160.586 174.072 186.969 1.00 22.47 ? 414 PRO B CA  1 
ATOM 7254 C C   . PRO B 1 430 ? 159.418 173.539 187.785 1.00 22.47 ? 414 PRO B C   1 
ATOM 7255 O O   . PRO B 1 430 ? 158.793 172.547 187.398 1.00 22.47 ? 414 PRO B O   1 
ATOM 7256 C CB  . PRO B 1 430 ? 161.079 173.021 185.961 1.00 22.47 ? 414 PRO B CB  1 
ATOM 7257 C CG  . PRO B 1 430 ? 162.585 173.023 186.072 1.00 22.47 ? 414 PRO B CG  1 
ATOM 7258 C CD  . PRO B 1 430 ? 162.877 173.419 187.477 1.00 22.47 ? 414 PRO B CD  1 
ATOM 7259 N N   . TYR B 1 431 ? 159.111 174.186 188.906 1.00 18.02 ? 415 TYR B N   1 
ATOM 7260 C CA  . TYR B 1 431 ? 157.964 173.816 189.727 1.00 18.02 ? 415 TYR B CA  1 
ATOM 7261 C C   . TYR B 1 431 ? 157.670 174.972 190.673 1.00 18.02 ? 415 TYR B C   1 
ATOM 7262 O O   . TYR B 1 431 ? 158.417 175.952 190.738 1.00 18.02 ? 415 TYR B O   1 
ATOM 7263 C CB  . TYR B 1 431 ? 158.206 172.521 190.509 1.00 18.02 ? 415 TYR B CB  1 
ATOM 7264 C CG  . TYR B 1 431 ? 159.554 172.449 191.183 1.00 18.02 ? 415 TYR B CG  1 
ATOM 7265 C CD1 . TYR B 1 431 ? 159.727 172.915 192.479 1.00 18.02 ? 415 TYR B CD1 1 
ATOM 7266 C CD2 . TYR B 1 431 ? 160.652 171.908 190.530 1.00 18.02 ? 415 TYR B CD2 1 
ATOM 7267 C CE1 . TYR B 1 431 ? 160.955 172.850 193.103 1.00 18.02 ? 415 TYR B CE1 1 
ATOM 7268 C CE2 . TYR B 1 431 ? 161.883 171.839 191.145 1.00 18.02 ? 415 TYR B CE2 1 
ATOM 7269 C CZ  . TYR B 1 431 ? 162.030 172.312 192.432 1.00 18.02 ? 415 TYR B CZ  1 
ATOM 7270 O OH  . TYR B 1 431 ? 163.257 172.244 193.050 1.00 18.02 ? 415 TYR B OH  1 
ATOM 7271 N N   . VAL B 1 432 ? 156.566 174.844 191.409 1.00 16.91 ? 416 VAL B N   1 
ATOM 7272 C CA  . VAL B 1 432 ? 156.135 175.863 192.355 1.00 16.91 ? 416 VAL B CA  1 
ATOM 7273 C C   . VAL B 1 432 ? 155.771 175.198 193.675 1.00 16.91 ? 416 VAL B C   1 
ATOM 7274 O O   . VAL B 1 432 ? 155.460 174.007 193.737 1.00 16.91 ? 416 VAL B O   1 
ATOM 7275 C CB  . VAL B 1 432 ? 154.941 176.684 191.824 1.00 16.91 ? 416 VAL B CB  1 
ATOM 7276 C CG1 . VAL B 1 432 ? 155.422 177.763 190.868 1.00 16.91 ? 416 VAL B CG1 1 
ATOM 7277 C CG2 . VAL B 1 432 ? 153.930 175.772 191.148 1.00 16.91 ? 416 VAL B CG2 1 
ATOM 7278 N N   . LEU B 1 433 ? 155.818 175.994 194.740 1.00 15.59 ? 417 LEU B N   1 
ATOM 7279 C CA  . LEU B 1 433 ? 155.437 175.518 196.057 1.00 15.59 ? 417 LEU B CA  1 
ATOM 7280 C C   . LEU B 1 433 ? 153.925 175.311 196.126 1.00 15.59 ? 417 LEU B C   1 
ATOM 7281 O O   . LEU B 1 433 ? 153.167 175.949 195.392 1.00 15.59 ? 417 LEU B O   1 
ATOM 7282 C CB  . LEU B 1 433 ? 155.881 176.509 197.132 1.00 15.59 ? 417 LEU B CB  1 
ATOM 7283 C CG  . LEU B 1 433 ? 157.303 176.394 197.689 1.00 15.59 ? 417 LEU B CG  1 
ATOM 7284 C CD1 . LEU B 1 433 ? 158.350 176.578 196.603 1.00 15.59 ? 417 LEU B CD1 1 
ATOM 7285 C CD2 . LEU B 1 433 ? 157.512 177.400 198.810 1.00 15.59 ? 417 LEU B CD2 1 
ATOM 7286 N N   . PRO B 1 434 ? 153.463 174.412 196.999 1.00 16.38 ? 418 PRO B N   1 
ATOM 7287 C CA  . PRO B 1 434 ? 152.012 174.198 197.123 1.00 16.38 ? 418 PRO B CA  1 
ATOM 7288 C C   . PRO B 1 434 ? 151.247 175.431 197.574 1.00 16.38 ? 418 PRO B C   1 
ATOM 7289 O O   . PRO B 1 434 ? 150.040 175.523 197.321 1.00 16.38 ? 418 PRO B O   1 
ATOM 7290 C CB  . PRO B 1 434 ? 151.916 173.065 198.154 1.00 16.38 ? 418 PRO B CB  1 
ATOM 7291 C CG  . PRO B 1 434 ? 153.224 172.354 198.046 1.00 16.38 ? 418 PRO B CG  1 
ATOM 7292 C CD  . PRO B 1 434 ? 154.230 173.437 197.792 1.00 16.38 ? 418 PRO B CD  1 
ATOM 7293 N N   . PHE B 1 435 ? 151.905 176.381 198.235 1.00 15.00 ? 419 PHE B N   1 
ATOM 7294 C CA  . PHE B 1 435 ? 151.247 177.591 198.711 1.00 15.00 ? 419 PHE B CA  1 
ATOM 7295 C C   . PHE B 1 435 ? 152.206 178.765 198.536 1.00 15.00 ? 419 PHE B C   1 
ATOM 7296 O O   . PHE B 1 435 ? 153.276 178.636 197.934 1.00 15.00 ? 419 PHE B O   1 
ATOM 7297 C CB  . PHE B 1 435 ? 150.787 177.425 200.165 1.00 15.00 ? 419 PHE B CB  1 
ATOM 7298 C CG  . PHE B 1 435 ? 151.741 176.640 201.020 1.00 15.00 ? 419 PHE B CG  1 
ATOM 7299 C CD1 . PHE B 1 435 ? 153.060 177.037 201.161 1.00 15.00 ? 419 PHE B CD1 1 
ATOM 7300 C CD2 . PHE B 1 435 ? 151.317 175.506 201.686 1.00 15.00 ? 419 PHE B CD2 1 
ATOM 7301 C CE1 . PHE B 1 435 ? 153.934 176.316 201.945 1.00 15.00 ? 419 PHE B CE1 1 
ATOM 7302 C CE2 . PHE B 1 435 ? 152.188 174.783 202.470 1.00 15.00 ? 419 PHE B CE2 1 
ATOM 7303 C CZ  . PHE B 1 435 ? 153.497 175.190 202.602 1.00 15.00 ? 419 PHE B CZ  1 
ATOM 7304 N N   . ALA B 1 436 ? 151.816 179.920 199.071 1.00 12.52 ? 420 ALA B N   1 
ATOM 7305 C CA  . ALA B 1 436 ? 152.623 181.127 198.963 1.00 12.52 ? 420 ALA B CA  1 
ATOM 7306 C C   . ALA B 1 436 ? 152.238 182.082 200.082 1.00 12.52 ? 420 ALA B C   1 
ATOM 7307 O O   . ALA B 1 436 ? 151.202 181.922 200.733 1.00 12.52 ? 420 ALA B O   1 
ATOM 7308 C CB  . ALA B 1 436 ? 152.451 181.800 197.599 1.00 12.52 ? 420 ALA B CB  1 
ATOM 7309 N N   . GLY B 1 437 ? 153.091 183.080 200.295 1.00 13.85 ? 421 GLY B N   1 
ATOM 7310 C CA  . GLY B 1 437 ? 152.859 184.074 201.325 1.00 13.85 ? 421 GLY B CA  1 
ATOM 7311 C C   . GLY B 1 437 ? 154.096 184.366 202.148 1.00 13.85 ? 421 GLY B C   1 
ATOM 7312 O O   . GLY B 1 437 ? 155.208 184.409 201.614 1.00 13.85 ? 421 GLY B O   1 
ATOM 7313 N N   . ARG B 1 438 ? 153.916 184.572 203.449 1.00 14.76 ? 422 ARG B N   1 
ATOM 7314 C CA  . ARG B 1 438 ? 155.020 184.787 204.381 1.00 14.76 ? 422 ARG B CA  1 
ATOM 7315 C C   . ARG B 1 438 ? 155.239 183.456 205.099 1.00 14.76 ? 422 ARG B C   1 
ATOM 7316 O O   . ARG B 1 438 ? 154.357 182.955 205.798 1.00 14.76 ? 422 ARG B O   1 
ATOM 7317 C CB  . ARG B 1 438 ? 154.713 185.935 205.351 1.00 14.76 ? 422 ARG B CB  1 
ATOM 7318 C CG  . ARG B 1 438 ? 155.242 185.752 206.770 1.00 14.76 ? 422 ARG B CG  1 
ATOM 7319 C CD  . ARG B 1 438 ? 156.759 185.879 206.825 1.00 14.76 ? 422 ARG B CD  1 
ATOM 7320 N NE  . ARG B 1 438 ? 157.256 185.924 208.195 1.00 14.76 ? 422 ARG B NE  1 
ATOM 7321 C CZ  . ARG B 1 438 ? 158.537 185.852 208.530 1.00 14.76 ? 422 ARG B CZ  1 
ATOM 7322 N NH1 . ARG B 1 438 ? 159.485 185.732 207.614 1.00 14.76 ? 422 ARG B NH1 1 
ATOM 7323 N NH2 . ARG B 1 438 ? 158.876 185.901 209.814 1.00 14.76 ? 422 ARG B NH2 1 
ATOM 7324 N N   . MET B 1 439 ? 156.417 182.874 204.901 1.00 11.66 ? 423 MET B N   1 
ATOM 7325 C CA  . MET B 1 439 ? 156.741 181.569 205.455 1.00 11.66 ? 423 MET B CA  1 
ATOM 7326 C C   . MET B 1 439 ? 158.035 181.630 206.259 1.00 11.66 ? 423 MET B C   1 
ATOM 7327 O O   . MET B 1 439 ? 158.795 182.599 206.201 1.00 11.66 ? 423 MET B O   1 
ATOM 7328 C CB  . MET B 1 439 ? 156.860 180.527 204.340 1.00 11.66 ? 423 MET B CB  1 
ATOM 7329 C CG  . MET B 1 439 ? 157.535 181.036 203.082 1.00 11.66 ? 423 MET B CG  1 
ATOM 7330 S SD  . MET B 1 439 ? 157.496 179.812 201.763 1.00 11.66 ? 423 MET B SD  1 
ATOM 7331 C CE  . MET B 1 439 ? 155.803 179.251 201.889 1.00 11.66 ? 423 MET B CE  1 
ATOM 7332 N N   . HIS B 1 440 ? 158.277 180.566 207.020 1.00 11.81 ? 424 HIS B N   1 
ATOM 7333 C CA  . HIS B 1 440 ? 159.508 180.408 207.779 1.00 11.81 ? 424 HIS B CA  1 
ATOM 7334 C C   . HIS B 1 440 ? 160.113 179.054 207.451 1.00 11.81 ? 424 HIS B C   1 
ATOM 7335 O O   . HIS B 1 440 ? 159.399 178.051 207.369 1.00 11.81 ? 424 HIS B O   1 
ATOM 7336 C CB  . HIS B 1 440 ? 159.261 180.527 209.288 1.00 11.81 ? 424 HIS B CB  1 
ATOM 7337 C CG  . HIS B 1 440 ? 160.461 180.975 210.062 1.00 11.81 ? 424 HIS B CG  1 
ATOM 7338 N ND1 . HIS B 1 440 ? 161.571 180.178 210.241 1.00 11.81 ? 424 HIS B ND1 1 
ATOM 7339 C CD2 . HIS B 1 440 ? 160.726 182.138 210.704 1.00 11.81 ? 424 HIS B CD2 1 
ATOM 7340 C CE1 . HIS B 1 440 ? 162.468 180.830 210.959 1.00 11.81 ? 424 HIS B CE1 1 
ATOM 7341 N NE2 . HIS B 1 440 ? 161.980 182.022 211.253 1.00 11.81 ? 424 HIS B NE2 1 
ATOM 7342 N N   . ALA B 1 441 ? 161.429 179.028 207.263 1.00 8.85  ? 425 ALA B N   1 
ATOM 7343 C CA  . ALA B 1 441 ? 162.139 177.814 206.894 1.00 8.85  ? 425 ALA B CA  1 
ATOM 7344 C C   . ALA B 1 441 ? 163.301 177.585 207.847 1.00 8.85  ? 425 ALA B C   1 
ATOM 7345 O O   . ALA B 1 441 ? 163.918 178.532 208.342 1.00 8.85  ? 425 ALA B O   1 
ATOM 7346 C CB  . ALA B 1 441 ? 162.654 177.881 205.451 1.00 8.85  ? 425 ALA B CB  1 
ATOM 7347 N N   . ALA B 1 442 ? 163.591 176.311 208.101 1.00 5.71  ? 426 ALA B N   1 
ATOM 7348 C CA  . ALA B 1 442 ? 164.701 175.933 208.971 1.00 5.71  ? 426 ALA B CA  1 
ATOM 7349 C C   . ALA B 1 442 ? 165.168 174.549 208.557 1.00 5.71  ? 426 ALA B C   1 
ATOM 7350 O O   . ALA B 1 442 ? 164.397 173.589 208.644 1.00 5.71  ? 426 ALA B O   1 
ATOM 7351 C CB  . ALA B 1 442 ? 164.282 175.948 210.440 1.00 5.71  ? 426 ALA B CB  1 
ATOM 7352 N N   . VAL B 1 443 ? 166.421 174.446 208.109 1.00 4.95  ? 427 VAL B N   1 
ATOM 7353 C CA  . VAL B 1 443 ? 166.918 173.176 207.596 1.00 4.95  ? 427 VAL B CA  1 
ATOM 7354 C C   . VAL B 1 443 ? 166.964 172.136 208.710 1.00 4.95  ? 427 VAL B C   1 
ATOM 7355 O O   . VAL B 1 443 ? 167.040 172.450 209.904 1.00 4.95  ? 427 VAL B O   1 
ATOM 7356 C CB  . VAL B 1 443 ? 168.299 173.349 206.945 1.00 4.95  ? 427 VAL B CB  1 
ATOM 7357 C CG1 . VAL B 1 443 ? 168.175 174.118 205.645 1.00 4.95  ? 427 VAL B CG1 1 
ATOM 7358 C CG2 . VAL B 1 443 ? 169.248 174.054 207.898 1.00 4.95  ? 427 VAL B CG2 1 
ATOM 7359 N N   . HIS B 1 444 ? 166.910 170.870 208.303 1.00 3.55  ? 428 HIS B N   1 
ATOM 7360 C CA  . HIS B 1 444 ? 166.987 169.756 209.243 1.00 3.55  ? 428 HIS B CA  1 
ATOM 7361 C C   . HIS B 1 444 ? 167.574 168.572 208.489 1.00 3.55  ? 428 HIS B C   1 
ATOM 7362 O O   . HIS B 1 444 ? 166.959 168.087 207.534 1.00 3.55  ? 428 HIS B O   1 
ATOM 7363 C CB  . HIS B 1 444 ? 165.614 169.427 209.814 1.00 3.55  ? 428 HIS B CB  1 
ATOM 7364 C CG  . HIS B 1 444 ? 165.628 168.318 210.817 1.00 3.55  ? 428 HIS B CG  1 
ATOM 7365 N ND1 . HIS B 1 444 ? 165.135 167.060 210.543 1.00 3.55  ? 428 HIS B ND1 1 
ATOM 7366 C CD2 . HIS B 1 444 ? 166.074 168.276 212.095 1.00 3.55  ? 428 HIS B CD2 1 
ATOM 7367 C CE1 . HIS B 1 444 ? 165.277 166.292 211.608 1.00 3.55  ? 428 HIS B CE1 1 
ATOM 7368 N NE2 . HIS B 1 444 ? 165.844 167.006 212.564 1.00 3.55  ? 428 HIS B NE2 1 
ATOM 7369 N N   . LYS B 1 445 ? 168.751 168.115 208.920 1.00 2.05  ? 429 LYS B N   1 
ATOM 7370 C CA  . LYS B 1 445 ? 169.504 167.082 208.216 1.00 2.05  ? 429 LYS B CA  1 
ATOM 7371 C C   . LYS B 1 445 ? 169.716 167.485 206.762 1.00 2.05  ? 429 LYS B C   1 
ATOM 7372 O O   . LYS B 1 445 ? 170.494 168.399 206.474 1.00 2.05  ? 429 LYS B O   1 
ATOM 7373 C CB  . LYS B 1 445 ? 168.797 165.726 208.307 1.00 2.05  ? 429 LYS B CB  1 
ATOM 7374 C CG  . LYS B 1 445 ? 168.129 165.457 209.647 1.00 2.05  ? 429 LYS B CG  1 
ATOM 7375 C CD  . LYS B 1 445 ? 169.152 165.290 210.757 1.00 2.05  ? 429 LYS B CD  1 
ATOM 7376 C CE  . LYS B 1 445 ? 169.770 163.904 210.738 1.00 2.05  ? 429 LYS B CE  1 
ATOM 7377 N NZ  . LYS B 1 445 ? 170.585 163.653 211.958 1.00 2.05  ? 429 LYS B NZ  1 
ATOM 7378 N N   . ASP B 1 446 ? 169.032 166.810 205.839 1.00 2.01  ? 430 ASP B N   1 
ATOM 7379 C CA  . ASP B 1 446 ? 169.106 167.133 204.420 1.00 2.01  ? 430 ASP B CA  1 
ATOM 7380 C C   . ASP B 1 446 ? 167.812 167.737 203.888 1.00 2.01  ? 430 ASP B C   1 
ATOM 7381 O O   . ASP B 1 446 ? 167.668 167.896 202.671 1.00 2.01  ? 430 ASP B O   1 
ATOM 7382 C CB  . ASP B 1 446 ? 169.470 165.886 203.610 1.00 2.01  ? 430 ASP B CB  1 
ATOM 7383 C CG  . ASP B 1 446 ? 170.837 165.335 203.967 1.00 2.01  ? 430 ASP B CG  1 
ATOM 7384 O OD1 . ASP B 1 446 ? 171.349 165.661 205.057 1.00 2.01  ? 430 ASP B OD1 1 
ATOM 7385 O OD2 . ASP B 1 446 ? 171.401 164.574 203.154 1.00 2.01  ? 430 ASP B OD2 1 
ATOM 7386 N N   . LEU B 1 447 ? 166.872 168.077 204.762 1.00 2.18  ? 431 LEU B N   1 
ATOM 7387 C CA  . LEU B 1 447 ? 165.584 168.621 204.361 1.00 2.18  ? 431 LEU B CA  1 
ATOM 7388 C C   . LEU B 1 447 ? 165.495 170.107 204.690 1.00 2.18  ? 431 LEU B C   1 
ATOM 7389 O O   . LEU B 1 447 ? 166.225 170.628 205.537 1.00 2.18  ? 431 LEU B O   1 
ATOM 7390 C CB  . LEU B 1 447 ? 164.441 167.869 205.047 1.00 2.18  ? 431 LEU B CB  1 
ATOM 7391 C CG  . LEU B 1 447 ? 164.413 166.355 204.861 1.00 2.18  ? 431 LEU B CG  1 
ATOM 7392 C CD1 . LEU B 1 447 ? 163.106 165.784 205.377 1.00 2.18  ? 431 LEU B CD1 1 
ATOM 7393 C CD2 . LEU B 1 447 ? 164.613 166.002 203.402 1.00 2.18  ? 431 LEU B CD2 1 
ATOM 7394 N N   . VAL B 1 448 ? 164.579 170.786 204.003 1.00 2.46  ? 432 VAL B N   1 
ATOM 7395 C CA  . VAL B 1 448 ? 164.317 172.210 204.214 1.00 2.46  ? 432 VAL B CA  1 
ATOM 7396 C C   . VAL B 1 448 ? 162.828 172.329 204.525 1.00 2.46  ? 432 VAL B C   1 
ATOM 7397 O O   . VAL B 1 448 ? 161.993 172.417 203.620 1.00 2.46  ? 432 VAL B O   1 
ATOM 7398 C CB  . VAL B 1 448 ? 164.702 173.068 203.007 1.00 2.46  ? 432 VAL B CB  1 
ATOM 7399 C CG1 . VAL B 1 448 ? 164.444 174.535 203.298 1.00 2.46  ? 432 VAL B CG1 1 
ATOM 7400 C CG2 . VAL B 1 448 ? 166.158 172.845 202.640 1.00 2.46  ? 432 VAL B CG2 1 
ATOM 7401 N N   . PHE B 1 449 ? 162.485 172.333 205.809 1.00 3.67  ? 433 PHE B N   1 
ATOM 7402 C CA  . PHE B 1 449 ? 161.089 172.403 206.212 1.00 3.67  ? 433 PHE B CA  1 
ATOM 7403 C C   . PHE B 1 449 ? 160.492 173.763 205.866 1.00 3.67  ? 433 PHE B C   1 
ATOM 7404 O O   . PHE B 1 449 ? 161.170 174.792 205.900 1.00 3.67  ? 433 PHE B O   1 
ATOM 7405 C CB  . PHE B 1 449 ? 160.953 172.141 207.710 1.00 3.67  ? 433 PHE B CB  1 
ATOM 7406 C CG  . PHE B 1 449 ? 160.986 170.687 208.078 1.00 3.67  ? 433 PHE B CG  1 
ATOM 7407 C CD1 . PHE B 1 449 ? 162.149 169.951 207.947 1.00 3.67  ? 433 PHE B CD1 1 
ATOM 7408 C CD2 . PHE B 1 449 ? 159.852 170.057 208.558 1.00 3.67  ? 433 PHE B CD2 1 
ATOM 7409 C CE1 . PHE B 1 449 ? 162.180 168.616 208.287 1.00 3.67  ? 433 PHE B CE1 1 
ATOM 7410 C CE2 . PHE B 1 449 ? 159.878 168.721 208.900 1.00 3.67  ? 433 PHE B CE2 1 
ATOM 7411 C CZ  . PHE B 1 449 ? 161.043 168.000 208.764 1.00 3.67  ? 433 PHE B CZ  1 
ATOM 7412 N N   . ILE B 1 450 ? 159.205 173.757 205.526 1.00 5.43  ? 434 ILE B N   1 
ATOM 7413 C CA  . ILE B 1 450 ? 158.476 174.963 205.153 1.00 5.43  ? 434 ILE B CA  1 
ATOM 7414 C C   . ILE B 1 450 ? 157.188 175.017 205.962 1.00 5.43  ? 434 ILE B C   1 
ATOM 7415 O O   . ILE B 1 450 ? 156.468 174.017 206.055 1.00 5.43  ? 434 ILE B O   1 
ATOM 7416 C CB  . ILE B 1 450 ? 158.166 175.002 203.645 1.00 5.43  ? 434 ILE B CB  1 
ATOM 7417 C CG1 . ILE B 1 450 ? 159.457 175.040 202.829 1.00 5.43  ? 434 ILE B CG1 1 
ATOM 7418 C CG2 . ILE B 1 450 ? 157.302 176.201 203.310 1.00 5.43  ? 434 ILE B CG2 1 
ATOM 7419 C CD1 . ILE B 1 450 ? 159.242 174.833 201.347 1.00 5.43  ? 434 ILE B CD1 1 
ATOM 7420 N N   . VAL B 1 451 ? 156.901 176.179 206.546 1.00 8.94  ? 435 VAL B N   1 
ATOM 7421 C CA  . VAL B 1 451 ? 155.671 176.405 207.296 1.00 8.94  ? 435 VAL B CA  1 
ATOM 7422 C C   . VAL B 1 451 ? 154.978 177.630 206.719 1.00 8.94  ? 435 VAL B C   1 
ATOM 7423 O O   . VAL B 1 451 ? 155.567 178.715 206.671 1.00 8.94  ? 435 VAL B O   1 
ATOM 7424 C CB  . VAL B 1 451 ? 155.939 176.604 208.799 1.00 8.94  ? 435 VAL B CB  1 
ATOM 7425 C CG1 . VAL B 1 451 ? 154.667 177.036 209.507 1.00 8.94  ? 435 VAL B CG1 1 
ATOM 7426 C CG2 . VAL B 1 451 ? 156.490 175.335 209.413 1.00 8.94  ? 435 VAL B CG2 1 
ATOM 7427 N N   . ALA B 1 452 ? 153.733 177.460 206.292 1.00 16.71 ? 436 ALA B N   1 
ATOM 7428 C CA  . ALA B 1 452 ? 152.934 178.543 205.748 1.00 16.71 ? 436 ALA B CA  1 
ATOM 7429 C C   . ALA B 1 452 ? 151.941 179.031 206.802 1.00 16.71 ? 436 ALA B C   1 
ATOM 7430 O O   . ALA B 1 452 ? 152.005 178.651 207.975 1.00 16.71 ? 436 ALA B O   1 
ATOM 7431 C CB  . ALA B 1 452 ? 152.228 178.088 204.470 1.00 16.71 ? 436 ALA B CB  1 
ATOM 7432 N N   . GLU B 1 453 ? 151.011 179.886 206.384 1.00 22.26 ? 437 GLU B N   1 
ATOM 7433 C CA  . GLU B 1 453 ? 149.986 180.413 207.281 1.00 22.26 ? 437 GLU B CA  1 
ATOM 7434 C C   . GLU B 1 453 ? 148.952 179.321 207.521 1.00 22.26 ? 437 GLU B C   1 
ATOM 7435 O O   . GLU B 1 453 ? 147.915 179.271 206.856 1.00 22.26 ? 437 GLU B O   1 
ATOM 7436 C CB  . GLU B 1 453 ? 149.348 181.664 206.690 1.00 22.26 ? 437 GLU B CB  1 
ATOM 7437 C CG  . GLU B 1 453 ? 150.061 182.957 207.053 1.00 22.26 ? 437 GLU B CG  1 
ATOM 7438 C CD  . GLU B 1 453 ? 149.137 184.160 207.035 1.00 22.26 ? 437 GLU B CD  1 
ATOM 7439 O OE1 . GLU B 1 453 ? 149.645 185.301 207.001 1.00 22.26 ? 437 GLU B OE1 1 
ATOM 7440 O OE2 . GLU B 1 453 ? 147.903 183.966 207.055 1.00 22.26 ? 437 GLU B OE2 1 
ATOM 7441 N N   . GLY B 1 454 ? 149.233 178.439 208.478 1.00 20.00 ? 438 GLY B N   1 
ATOM 7442 C CA  . GLY B 1 454 ? 148.332 177.349 208.794 1.00 20.00 ? 438 GLY B CA  1 
ATOM 7443 C C   . GLY B 1 454 ? 149.046 176.043 209.074 1.00 20.00 ? 438 GLY B C   1 
ATOM 7444 O O   . GLY B 1 454 ? 150.276 176.010 209.180 1.00 20.00 ? 438 GLY B O   1 
ATOM 7445 N N   . ASP B 1 455 ? 148.283 174.956 209.198 1.00 20.98 ? 439 ASP B N   1 
ATOM 7446 C CA  . ASP B 1 455 ? 148.846 173.633 209.468 1.00 20.98 ? 439 ASP B CA  1 
ATOM 7447 C C   . ASP B 1 455 ? 149.125 172.947 208.134 1.00 20.98 ? 439 ASP B C   1 
ATOM 7448 O O   . ASP B 1 455 ? 148.435 172.016 207.712 1.00 20.98 ? 439 ASP B O   1 
ATOM 7449 C CB  . ASP B 1 455 ? 147.899 172.818 210.340 1.00 20.98 ? 439 ASP B CB  1 
ATOM 7450 C CG  . ASP B 1 455 ? 147.467 173.564 211.587 1.00 20.98 ? 439 ASP B CG  1 
ATOM 7451 O OD1 . ASP B 1 455 ? 147.923 174.711 211.782 1.00 20.98 ? 439 ASP B OD1 1 
ATOM 7452 O OD2 . ASP B 1 455 ? 146.672 173.006 212.371 1.00 20.98 ? 439 ASP B OD2 1 
ATOM 7453 N N   . SER B 1 456 ? 150.167 173.425 207.461 1.00 12.38 ? 440 SER B N   1 
ATOM 7454 C CA  . SER B 1 456 ? 150.487 173.000 206.102 1.00 12.38 ? 440 SER B CA  1 
ATOM 7455 C C   . SER B 1 456 ? 151.979 172.704 205.971 1.00 12.38 ? 440 SER B C   1 
ATOM 7456 O O   . SER B 1 456 ? 152.657 173.204 205.074 1.00 12.38 ? 440 SER B O   1 
ATOM 7457 C CB  . SER B 1 456 ? 150.044 174.054 205.091 1.00 12.38 ? 440 SER B CB  1 
ATOM 7458 O OG  . SER B 1 456 ? 150.710 175.283 205.315 1.00 12.38 ? 440 SER B OG  1 
ATOM 7459 N N   . LEU B 1 457 ? 152.511 171.902 206.894 1.00 9.36  ? 441 LEU B N   1 
ATOM 7460 C CA  . LEU B 1 457 ? 153.923 171.538 206.851 1.00 9.36  ? 441 LEU B CA  1 
ATOM 7461 C C   . LEU B 1 457 ? 154.287 170.909 205.512 1.00 9.36  ? 441 LEU B C   1 
ATOM 7462 O O   . LEU B 1 457 ? 153.594 170.013 205.024 1.00 9.36  ? 441 LEU B O   1 
ATOM 7463 C CB  . LEU B 1 457 ? 154.253 170.561 207.979 1.00 9.36  ? 441 LEU B CB  1 
ATOM 7464 C CG  . LEU B 1 457 ? 155.693 170.597 208.491 1.00 9.36  ? 441 LEU B CG  1 
ATOM 7465 C CD1 . LEU B 1 457 ? 155.929 171.812 209.367 1.00 9.36  ? 441 LEU B CD1 1 
ATOM 7466 C CD2 . LEU B 1 457 ? 156.046 169.313 209.221 1.00 9.36  ? 441 LEU B CD2 1 
ATOM 7467 N N   . VAL B 1 458 ? 155.382 171.381 204.921 1.00 5.71  ? 442 VAL B N   1 
ATOM 7468 C CA  . VAL B 1 458 ? 155.890 170.862 203.658 1.00 5.71  ? 442 VAL B CA  1 
ATOM 7469 C C   . VAL B 1 458 ? 157.388 170.637 203.798 1.00 5.71  ? 442 VAL B C   1 
ATOM 7470 O O   . VAL B 1 458 ? 158.119 171.544 204.211 1.00 5.71  ? 442 VAL B O   1 
ATOM 7471 C CB  . VAL B 1 458 ? 155.589 171.813 202.483 1.00 5.71  ? 442 VAL B CB  1 
ATOM 7472 C CG1 . VAL B 1 458 ? 156.431 171.449 201.273 1.00 5.71  ? 442 VAL B CG1 1 
ATOM 7473 C CG2 . VAL B 1 458 ? 154.116 171.758 202.130 1.00 5.71  ? 442 VAL B CG2 1 
ATOM 7474 N N   . CYS B 1 459 ? 157.843 169.435 203.455 1.00 5.02  ? 443 CYS B N   1 
ATOM 7475 C CA  . CYS B 1 459 ? 159.255 169.080 203.517 1.00 5.02  ? 443 CYS B CA  1 
ATOM 7476 C C   . CYS B 1 459 ? 159.851 169.164 202.118 1.00 5.02  ? 443 CYS B C   1 
ATOM 7477 O O   . CYS B 1 459 ? 159.365 168.508 201.192 1.00 5.02  ? 443 CYS B O   1 
ATOM 7478 C CB  . CYS B 1 459 ? 159.442 167.678 204.095 1.00 5.02  ? 443 CYS B CB  1 
ATOM 7479 S SG  . CYS B 1 459 ? 158.770 167.454 205.756 1.00 5.02  ? 443 CYS B SG  1 
ATOM 7480 N N   . TYR B 1 460 ? 160.896 169.967 201.970 1.00 5.90  ? 444 TYR B N   1 
ATOM 7481 C CA  . TYR B 1 460 ? 161.574 170.136 200.696 1.00 5.90  ? 444 TYR B CA  1 
ATOM 7482 C C   . TYR B 1 460 ? 162.722 169.140 200.575 1.00 5.90  ? 444 TYR B C   1 
ATOM 7483 O O   . TYR B 1 460 ? 163.201 168.582 201.564 1.00 5.90  ? 444 TYR B O   1 
ATOM 7484 C CB  . TYR B 1 460 ? 162.095 171.568 200.557 1.00 5.90  ? 444 TYR B CB  1 
ATOM 7485 C CG  . TYR B 1 460 ? 162.553 171.947 199.168 1.00 5.90  ? 444 TYR B CG  1 
ATOM 7486 C CD1 . TYR B 1 460 ? 161.638 172.323 198.198 1.00 5.90  ? 444 TYR B CD1 1 
ATOM 7487 C CD2 . TYR B 1 460 ? 163.899 171.944 198.831 1.00 5.90  ? 444 TYR B CD2 1 
ATOM 7488 C CE1 . TYR B 1 460 ? 162.045 172.674 196.928 1.00 5.90  ? 444 TYR B CE1 1 
ATOM 7489 C CE2 . TYR B 1 460 ? 164.317 172.294 197.562 1.00 5.90  ? 444 TYR B CE2 1 
ATOM 7490 C CZ  . TYR B 1 460 ? 163.385 172.659 196.615 1.00 5.90  ? 444 TYR B CZ  1 
ATOM 7491 O OH  . TYR B 1 460 ? 163.792 173.010 195.349 1.00 5.90  ? 444 TYR B OH  1 
ATOM 7492 N N   . ASN B 1 461 ? 163.157 168.914 199.340 1.00 6.23  ? 445 ASN B N   1 
ATOM 7493 C CA  . ASN B 1 461 ? 164.287 168.027 199.063 1.00 6.23  ? 445 ASN B CA  1 
ATOM 7494 C C   . ASN B 1 461 ? 164.922 168.462 197.753 1.00 6.23  ? 445 ASN B C   1 
ATOM 7495 O O   . ASN B 1 461 ? 164.443 168.098 196.668 1.00 6.23  ? 445 ASN B O   1 
ATOM 7496 C CB  . ASN B 1 461 ? 163.860 166.564 199.003 1.00 6.23  ? 445 ASN B CB  1 
ATOM 7497 C CG  . ASN B 1 461 ? 165.035 165.612 199.078 1.00 6.23  ? 445 ASN B CG  1 
ATOM 7498 O OD1 . ASN B 1 461 ? 165.659 165.297 198.065 1.00 6.23  ? 445 ASN B OD1 1 
ATOM 7499 N ND2 . ASN B 1 461 ? 165.346 165.149 200.281 1.00 6.23  ? 445 ASN B ND2 1 
ATOM 7500 N N   . PRO B 1 462 ? 165.997 169.250 197.808 1.00 7.98  ? 446 PRO B N   1 
ATOM 7501 C CA  . PRO B 1 462 ? 166.639 169.697 196.562 1.00 7.98  ? 446 PRO B CA  1 
ATOM 7502 C C   . PRO B 1 462 ? 167.170 168.563 195.703 1.00 7.98  ? 446 PRO B C   1 
ATOM 7503 O O   . PRO B 1 462 ? 167.134 168.667 194.470 1.00 7.98  ? 446 PRO B O   1 
ATOM 7504 C CB  . PRO B 1 462 ? 167.771 170.603 197.063 1.00 7.98  ? 446 PRO B CB  1 
ATOM 7505 C CG  . PRO B 1 462 ? 168.057 170.118 198.440 1.00 7.98  ? 446 PRO B CG  1 
ATOM 7506 C CD  . PRO B 1 462 ? 166.735 169.692 199.002 1.00 7.98  ? 446 PRO B CD  1 
ATOM 7507 N N   . LEU B 1 463 ? 167.666 167.483 196.312 1.00 7.05  ? 447 LEU B N   1 
ATOM 7508 C CA  . LEU B 1 463 ? 168.254 166.402 195.526 1.00 7.05  ? 447 LEU B CA  1 
ATOM 7509 C C   . LEU B 1 463 ? 167.196 165.656 194.722 1.00 7.05  ? 447 LEU B C   1 
ATOM 7510 O O   . LEU B 1 463 ? 167.366 165.441 193.516 1.00 7.05  ? 447 LEU B O   1 
ATOM 7511 C CB  . LEU B 1 463 ? 169.011 165.441 196.441 1.00 7.05  ? 447 LEU B CB  1 
ATOM 7512 C CG  . LEU B 1 463 ? 170.527 165.636 196.504 1.00 7.05  ? 447 LEU B CG  1 
ATOM 7513 C CD1 . LEU B 1 463 ? 171.128 165.595 195.108 1.00 7.05  ? 447 LEU B CD1 1 
ATOM 7514 C CD2 . LEU B 1 463 ? 170.878 166.938 197.204 1.00 7.05  ? 447 LEU B CD2 1 
ATOM 7515 N N   . LEU B 1 464 ? 166.099 165.257 195.365 1.00 6.49  ? 448 LEU B N   1 
ATOM 7516 C CA  . LEU B 1 464 ? 165.022 164.568 194.666 1.00 6.49  ? 448 LEU B CA  1 
ATOM 7517 C C   . LEU B 1 464 ? 164.046 165.522 193.996 1.00 6.49  ? 448 LEU B C   1 
ATOM 7518 O O   . LEU B 1 464 ? 163.202 165.071 193.214 1.00 6.49  ? 448 LEU B O   1 
ATOM 7519 C CB  . LEU B 1 464 ? 164.254 163.658 195.629 1.00 6.49  ? 448 LEU B CB  1 
ATOM 7520 C CG  . LEU B 1 464 ? 165.022 162.462 196.189 1.00 6.49  ? 448 LEU B CG  1 
ATOM 7521 C CD1 . LEU B 1 464 ? 164.073 161.514 196.898 1.00 6.49  ? 448 LEU B CD1 1 
ATOM 7522 C CD2 . LEU B 1 464 ? 165.774 161.747 195.082 1.00 6.49  ? 448 LEU B CD2 1 
ATOM 7523 N N   . ASP B 1 465 ? 164.146 166.820 194.287 1.00 9.77  ? 449 ASP B N   1 
ATOM 7524 C CA  . ASP B 1 465 ? 163.323 167.848 193.652 1.00 9.77  ? 449 ASP B CA  1 
ATOM 7525 C C   . ASP B 1 465 ? 161.834 167.553 193.843 1.00 9.77  ? 449 ASP B C   1 
ATOM 7526 O O   . ASP B 1 465 ? 161.038 167.618 192.905 1.00 9.77  ? 449 ASP B O   1 
ATOM 7527 C CB  . ASP B 1 465 ? 163.672 167.980 192.167 1.00 9.77  ? 449 ASP B CB  1 
ATOM 7528 C CG  . ASP B 1 465 ? 164.553 169.181 191.879 1.00 9.77  ? 449 ASP B CG  1 
ATOM 7529 O OD1 . ASP B 1 465 ? 164.206 170.296 192.313 1.00 9.77  ? 449 ASP B OD1 1 
ATOM 7530 O OD2 . ASP B 1 465 ? 165.595 169.007 191.213 1.00 9.77  ? 449 ASP B OD2 1 
ATOM 7531 N N   . SER B 1 466 ? 161.461 167.220 195.078 1.00 8.05  ? 450 SER B N   1 
ATOM 7532 C CA  . SER B 1 466 ? 160.091 166.839 195.391 1.00 8.05  ? 450 SER B CA  1 
ATOM 7533 C C   . SER B 1 466 ? 159.700 167.393 196.753 1.00 8.05  ? 450 SER B C   1 
ATOM 7534 O O   . SER B 1 466 ? 160.548 167.797 197.552 1.00 8.05  ? 450 SER B O   1 
ATOM 7535 C CB  . SER B 1 466 ? 159.910 165.317 195.371 1.00 8.05  ? 450 SER B CB  1 
ATOM 7536 O OG  . SER B 1 466 ? 158.929 164.914 196.310 1.00 8.05  ? 450 SER B OG  1 
ATOM 7537 N N   . PHE B 1 467 ? 158.393 167.406 197.008 1.00 8.97  ? 451 PHE B N   1 
ATOM 7538 C CA  . PHE B 1 467 ? 157.823 167.926 198.240 1.00 8.97  ? 451 PHE B CA  1 
ATOM 7539 C C   . PHE B 1 467 ? 157.115 166.818 199.009 1.00 8.97  ? 451 PHE B C   1 
ATOM 7540 O O   . PHE B 1 467 ? 157.025 165.674 198.555 1.00 8.97  ? 451 PHE B O   1 
ATOM 7541 C CB  . PHE B 1 467 ? 156.833 169.063 197.959 1.00 8.97  ? 451 PHE B CB  1 
ATOM 7542 C CG  . PHE B 1 467 ? 157.394 170.161 197.104 1.00 8.97  ? 451 PHE B CG  1 
ATOM 7543 C CD1 . PHE B 1 467 ? 158.094 171.209 197.672 1.00 8.97  ? 451 PHE B CD1 1 
ATOM 7544 C CD2 . PHE B 1 467 ? 157.230 170.139 195.732 1.00 8.97  ? 451 PHE B CD2 1 
ATOM 7545 C CE1 . PHE B 1 467 ? 158.607 172.219 196.886 1.00 8.97  ? 451 PHE B CE1 1 
ATOM 7546 C CE2 . PHE B 1 467 ? 157.744 171.145 194.942 1.00 8.97  ? 451 PHE B CE2 1 
ATOM 7547 C CZ  . PHE B 1 467 ? 158.435 172.186 195.521 1.00 8.97  ? 451 PHE B CZ  1 
ATOM 7548 N N   . THR B 1 468 ? 156.611 167.179 200.191 1.00 7.76  ? 452 THR B N   1 
ATOM 7549 C CA  . THR B 1 468 ? 155.863 166.252 201.043 1.00 7.76  ? 452 THR B CA  1 
ATOM 7550 C C   . THR B 1 468 ? 155.091 167.074 202.070 1.00 7.76  ? 452 THR B C   1 
ATOM 7551 O O   . THR B 1 468 ? 155.690 167.840 202.829 1.00 7.76  ? 452 THR B O   1 
ATOM 7552 C CB  . THR B 1 468 ? 156.784 165.254 201.729 1.00 7.76  ? 452 THR B CB  1 
ATOM 7553 O OG1 . THR B 1 468 ? 157.372 164.389 200.751 1.00 7.76  ? 452 THR B OG1 1 
ATOM 7554 C CG2 . THR B 1 468 ? 156.010 164.442 202.752 1.00 7.76  ? 452 THR B CG2 1 
ATOM 7555 N N   . ARG B 1 469 ? 153.775 166.898 202.099 1.00 13.33 ? 453 ARG B N   1 
ATOM 7556 C CA  . ARG B 1 469 ? 152.936 167.571 203.079 1.00 13.33 ? 453 ARG B CA  1 
ATOM 7557 C C   . ARG B 1 469 ? 152.565 166.583 204.187 1.00 13.33 ? 453 ARG B C   1 
ATOM 7558 O O   . ARG B 1 469 ? 153.002 165.430 204.180 1.00 13.33 ? 453 ARG B O   1 
ATOM 7559 C CB  . ARG B 1 469 ? 151.709 168.176 202.391 1.00 13.33 ? 453 ARG B CB  1 
ATOM 7560 C CG  . ARG B 1 469 ? 151.995 168.795 201.036 1.00 13.33 ? 453 ARG B CG  1 
ATOM 7561 C CD  . ARG B 1 469 ? 150.785 169.557 200.530 1.00 13.33 ? 453 ARG B CD  1 
ATOM 7562 N NE  . ARG B 1 469 ? 150.213 170.399 201.573 1.00 13.33 ? 453 ARG B NE  1 
ATOM 7563 C CZ  . ARG B 1 469 ? 149.136 171.157 201.418 1.00 13.33 ? 453 ARG B CZ  1 
ATOM 7564 N NH1 . ARG B 1 469 ? 148.488 171.210 200.267 1.00 13.33 ? 453 ARG B NH1 1 
ATOM 7565 N NH2 . ARG B 1 469 ? 148.700 171.881 202.445 1.00 13.33 ? 453 ARG B NH2 1 
ATOM 7566 N N   . LEU B 1 470 ? 151.758 167.025 205.152 1.00 14.35 ? 454 LEU B N   1 
ATOM 7567 C CA  . LEU B 1 470 ? 151.278 166.157 206.217 1.00 14.35 ? 454 LEU B CA  1 
ATOM 7568 C C   . LEU B 1 470 ? 149.762 166.076 206.307 1.00 14.35 ? 454 LEU B C   1 
ATOM 7569 O O   . LEU B 1 470 ? 149.258 165.259 207.086 1.00 14.35 ? 454 LEU B O   1 
ATOM 7570 C CB  . LEU B 1 470 ? 151.829 166.611 207.578 1.00 14.35 ? 454 LEU B CB  1 
ATOM 7571 C CG  . LEU B 1 470 ? 153.320 166.384 207.831 1.00 14.35 ? 454 LEU B CG  1 
ATOM 7572 C CD1 . LEU B 1 470 ? 153.644 166.592 209.301 1.00 14.35 ? 454 LEU B CD1 1 
ATOM 7573 C CD2 . LEU B 1 470 ? 153.743 164.997 207.377 1.00 14.35 ? 454 LEU B CD2 1 
ATOM 7574 N N   . CYS B 1 471 ? 149.025 166.886 205.541 1.00 19.03 ? 455 CYS B N   1 
ATOM 7575 C CA  . CYS B 1 471 ? 147.561 166.884 205.550 1.00 19.03 ? 455 CYS B CA  1 
ATOM 7576 C C   . CYS B 1 471 ? 147.015 167.090 206.963 1.00 19.03 ? 455 CYS B C   1 
ATOM 7577 O O   . CYS B 1 471 ? 146.091 166.406 207.406 1.00 19.03 ? 455 CYS B O   1 
ATOM 7578 C CB  . CYS B 1 471 ? 147.010 165.598 204.928 1.00 19.03 ? 455 CYS B CB  1 
ATOM 7579 S SG  . CYS B 1 471 ? 147.383 165.402 203.169 1.00 19.03 ? 455 CYS B SG  1 
ATOM 7580 N N   . LEU B 1 472 ? 147.604 168.050 207.674 1.00 20.74 ? 456 LEU B N   1 
ATOM 7581 C CA  . LEU B 1 472 ? 147.188 168.334 209.040 1.00 20.74 ? 456 LEU B CA  1 
ATOM 7582 C C   . LEU B 1 472 ? 145.816 169.007 209.048 1.00 20.74 ? 456 LEU B C   1 
ATOM 7583 O O   . LEU B 1 472 ? 145.608 170.000 208.345 1.00 20.74 ? 456 LEU B O   1 
ATOM 7584 C CB  . LEU B 1 472 ? 148.208 169.232 209.737 1.00 20.74 ? 456 LEU B CB  1 
ATOM 7585 C CG  . LEU B 1 472 ? 149.619 168.667 209.909 1.00 20.74 ? 456 LEU B CG  1 
ATOM 7586 C CD1 . LEU B 1 472 ? 150.562 169.738 210.432 1.00 20.74 ? 456 LEU B CD1 1 
ATOM 7587 C CD2 . LEU B 1 472 ? 149.608 167.460 210.834 1.00 20.74 ? 456 LEU B CD2 1 
ATOM 7588 N N   . PRO B 1 473 ? 144.868 168.484 209.822 1.00 22.87 ? 457 PRO B N   1 
ATOM 7589 C CA  . PRO B 1 473 ? 143.550 169.120 209.906 1.00 22.87 ? 457 PRO B CA  1 
ATOM 7590 C C   . PRO B 1 473 ? 143.633 170.505 210.527 1.00 22.87 ? 457 PRO B C   1 
ATOM 7591 O O   . PRO B 1 473 ? 144.510 170.797 211.344 1.00 22.87 ? 457 PRO B O   1 
ATOM 7592 C CB  . PRO B 1 473 ? 142.747 168.161 210.794 1.00 22.87 ? 457 PRO B CB  1 
ATOM 7593 C CG  . PRO B 1 473 ? 143.474 166.855 210.701 1.00 22.87 ? 457 PRO B CG  1 
ATOM 7594 C CD  . PRO B 1 473 ? 144.920 167.224 210.582 1.00 22.87 ? 457 PRO B CD  1 
ATOM 7595 N N   . GLU B 1 474 ? 142.699 171.364 210.125 1.00 25.22 ? 458 GLU B N   1 
ATOM 7596 C CA  . GLU B 1 474 ? 142.646 172.742 210.593 1.00 25.22 ? 458 GLU B CA  1 
ATOM 7597 C C   . GLU B 1 474 ? 141.858 172.899 211.887 1.00 25.22 ? 458 GLU B C   1 
ATOM 7598 O O   . GLU B 1 474 ? 141.498 174.026 212.245 1.00 25.22 ? 458 GLU B O   1 
ATOM 7599 C CB  . GLU B 1 474 ? 142.046 173.643 209.510 1.00 25.22 ? 458 GLU B CB  1 
ATOM 7600 C CG  . GLU B 1 474 ? 143.066 174.209 208.537 1.00 25.22 ? 458 GLU B CG  1 
ATOM 7601 C CD  . GLU B 1 474 ? 142.555 175.437 207.811 1.00 25.22 ? 458 GLU B CD  1 
ATOM 7602 O OE1 . GLU B 1 474 ? 141.350 175.479 207.487 1.00 25.22 ? 458 GLU B OE1 1 
ATOM 7603 O OE2 . GLU B 1 474 ? 143.358 176.362 207.566 1.00 25.22 ? 458 GLU B OE2 1 
ATOM 7604 N N   . ALA B 1 475 ? 141.580 171.803 212.593 1.00 25.31 ? 459 ALA B N   1 
ATOM 7605 C CA  . ALA B 1 475 ? 140.835 171.868 213.844 1.00 25.31 ? 459 ALA B CA  1 
ATOM 7606 C C   . ALA B 1 475 ? 141.633 172.488 214.983 1.00 25.31 ? 459 ALA B C   1 
ATOM 7607 O O   . ALA B 1 475 ? 141.046 172.797 216.026 1.00 25.31 ? 459 ALA B O   1 
ATOM 7608 C CB  . ALA B 1 475 ? 140.364 170.469 214.246 1.00 25.31 ? 459 ALA B CB  1 
ATOM 7609 N N   . TRP B 1 476 ? 142.941 172.679 214.815 1.00 26.36 ? 460 TRP B N   1 
ATOM 7610 C CA  . TRP B 1 476 ? 143.794 173.246 215.853 1.00 26.36 ? 460 TRP B CA  1 
ATOM 7611 C C   . TRP B 1 476 ? 143.966 174.753 215.708 1.00 26.36 ? 460 TRP B C   1 
ATOM 7612 O O   . TRP B 1 476 ? 143.951 175.478 216.707 1.00 26.36 ? 460 TRP B O   1 
ATOM 7613 C CB  . TRP B 1 476 ? 145.166 172.561 215.833 1.00 26.36 ? 460 TRP B CB  1 
ATOM 7614 C CG  . TRP B 1 476 ? 145.096 171.070 215.967 1.00 26.36 ? 460 TRP B CG  1 
ATOM 7615 C CD1 . TRP B 1 476 ? 144.075 170.341 216.503 1.00 26.36 ? 460 TRP B CD1 1 
ATOM 7616 C CD2 . TRP B 1 476 ? 146.085 170.123 215.545 1.00 26.36 ? 460 TRP B CD2 1 
ATOM 7617 N NE1 . TRP B 1 476 ? 144.369 169.000 216.447 1.00 26.36 ? 460 TRP B NE1 1 
ATOM 7618 C CE2 . TRP B 1 476 ? 145.598 168.840 215.862 1.00 26.36 ? 460 TRP B CE2 1 
ATOM 7619 C CE3 . TRP B 1 476 ? 147.337 170.237 214.932 1.00 26.36 ? 460 TRP B CE3 1 
ATOM 7620 C CZ2 . TRP B 1 476 ? 146.317 167.679 215.587 1.00 26.36 ? 460 TRP B CZ2 1 
ATOM 7621 C CZ3 . TRP B 1 476 ? 148.049 169.083 214.659 1.00 26.36 ? 460 TRP B CZ3 1 
ATOM 7622 C CH2 . TRP B 1 476 ? 147.538 167.822 214.987 1.00 26.36 ? 460 TRP B CH2 1 
ATOM 7623 N N   . SER B 1 477 ? 144.129 175.240 214.477 1.00 22.15 ? 461 SER B N   1 
ATOM 7624 C CA  . SER B 1 477 ? 144.312 176.668 214.219 1.00 22.15 ? 461 SER B CA  1 
ATOM 7625 C C   . SER B 1 477 ? 142.938 177.318 214.076 1.00 22.15 ? 461 SER B C   1 
ATOM 7626 O O   . SER B 1 477 ? 142.446 177.588 212.977 1.00 22.15 ? 461 SER B O   1 
ATOM 7627 C CB  . SER B 1 477 ? 145.169 176.884 212.978 1.00 22.15 ? 461 SER B CB  1 
ATOM 7628 O OG  . SER B 1 477 ? 146.400 176.191 213.081 1.00 22.15 ? 461 SER B OG  1 
ATOM 7629 N N   . SER B 1 478 ? 142.305 177.566 215.225 1.00 19.52 ? 462 SER B N   1 
ATOM 7630 C CA  . SER B 1 478 ? 140.998 178.217 215.227 1.00 19.52 ? 462 SER B CA  1 
ATOM 7631 C C   . SER B 1 478 ? 141.088 179.630 214.664 1.00 19.52 ? 462 SER B C   1 
ATOM 7632 O O   . SER B 1 478 ? 140.230 180.058 213.884 1.00 19.52 ? 462 SER B O   1 
ATOM 7633 C CB  . SER B 1 478 ? 140.425 178.234 216.645 1.00 19.52 ? 462 SER B CB  1 
ATOM 7634 O OG  . SER B 1 478 ? 139.147 178.846 216.670 1.00 19.52 ? 462 SER B OG  1 
ATOM 7635 N N   . ALA B 1 479 ? 142.127 180.370 215.050 1.00 20.01 ? 463 ALA B N   1 
ATOM 7636 C CA  . ALA B 1 479 ? 142.350 181.719 214.548 1.00 20.01 ? 463 ALA B CA  1 
ATOM 7637 C C   . ALA B 1 479 ? 143.582 181.744 213.661 1.00 20.01 ? 463 ALA B C   1 
ATOM 7638 O O   . ALA B 1 479 ? 144.630 181.212 214.056 1.00 20.01 ? 463 ALA B O   1 
ATOM 7639 C CB  . ALA B 1 479 ? 142.522 182.703 215.701 1.00 20.01 ? 463 ALA B CB  1 
ATOM 7640 N N   . PRO B 1 480 ? 143.504 182.334 212.467 1.00 19.93 ? 464 PRO B N   1 
ATOM 7641 C CA  . PRO B 1 480 ? 144.673 182.364 211.572 1.00 19.93 ? 464 PRO B CA  1 
ATOM 7642 C C   . PRO B 1 480 ? 145.784 183.221 212.161 1.00 19.93 ? 464 PRO B C   1 
ATOM 7643 O O   . PRO B 1 480 ? 145.609 184.421 212.384 1.00 19.93 ? 464 PRO B O   1 
ATOM 7644 C CB  . PRO B 1 480 ? 144.113 182.967 210.278 1.00 19.93 ? 464 PRO B CB  1 
ATOM 7645 C CG  . PRO B 1 480 ? 142.914 183.748 210.716 1.00 19.93 ? 464 PRO B CG  1 
ATOM 7646 C CD  . PRO B 1 480 ? 142.327 182.980 211.864 1.00 19.93 ? 464 PRO B CD  1 
ATOM 7647 N N   . SER B 1 481 ? 146.931 182.595 212.413 1.00 21.01 ? 465 SER B N   1 
ATOM 7648 C CA  . SER B 1 481 ? 148.072 183.285 212.993 1.00 21.01 ? 465 SER B CA  1 
ATOM 7649 C C   . SER B 1 481 ? 149.350 182.746 212.370 1.00 21.01 ? 465 SER B C   1 
ATOM 7650 O O   . SER B 1 481 ? 149.387 181.619 211.871 1.00 21.01 ? 465 SER B O   1 
ATOM 7651 C CB  . SER B 1 481 ? 148.115 183.122 214.517 1.00 21.01 ? 465 SER B CB  1 
ATOM 7652 O OG  . SER B 1 481 ? 148.962 184.091 215.110 1.00 21.01 ? 465 SER B OG  1 
ATOM 7653 N N   . LEU B 1 482 ? 150.396 183.567 212.399 1.00 22.03 ? 466 LEU B N   1 
ATOM 7654 C CA  . LEU B 1 482 ? 151.682 183.161 211.851 1.00 22.03 ? 466 LEU B CA  1 
ATOM 7655 C C   . LEU B 1 482 ? 152.314 182.075 212.713 1.00 22.03 ? 466 LEU B C   1 
ATOM 7656 O O   . LEU B 1 482 ? 152.206 182.091 213.942 1.00 22.03 ? 466 LEU B O   1 
ATOM 7657 C CB  . LEU B 1 482 ? 152.622 184.361 211.752 1.00 22.03 ? 466 LEU B CB  1 
ATOM 7658 C CG  . LEU B 1 482 ? 152.156 185.533 210.887 1.00 22.03 ? 466 LEU B CG  1 
ATOM 7659 C CD1 . LEU B 1 482 ? 153.192 186.646 210.891 1.00 22.03 ? 466 LEU B CD1 1 
ATOM 7660 C CD2 . LEU B 1 482 ? 151.873 185.069 209.468 1.00 22.03 ? 466 LEU B CD2 1 
ATOM 7661 N N   . TRP B 1 483 ? 152.977 181.127 212.058 1.00 24.80 ? 467 TRP B N   1 
ATOM 7662 C CA  . TRP B 1 483 ? 153.706 180.062 212.731 1.00 24.80 ? 467 TRP B CA  1 
ATOM 7663 C C   . TRP B 1 483 ? 155.181 180.136 212.358 1.00 24.80 ? 467 TRP B C   1 
ATOM 7664 O O   . TRP B 1 483 ? 155.526 180.318 211.186 1.00 24.80 ? 467 TRP B O   1 
ATOM 7665 C CB  . TRP B 1 483 ? 153.144 178.686 212.365 1.00 24.80 ? 467 TRP B CB  1 
ATOM 7666 C CG  . TRP B 1 483 ? 151.782 178.416 212.924 1.00 24.80 ? 467 TRP B CG  1 
ATOM 7667 C CD1 . TRP B 1 483 ? 150.594 178.886 212.450 1.00 24.80 ? 467 TRP B CD1 1 
ATOM 7668 C CD2 . TRP B 1 483 ? 151.467 177.607 214.064 1.00 24.80 ? 467 TRP B CD2 1 
ATOM 7669 N NE1 . TRP B 1 483 ? 149.558 178.422 213.224 1.00 24.80 ? 467 TRP B NE1 1 
ATOM 7670 C CE2 . TRP B 1 483 ? 150.068 177.634 214.222 1.00 24.80 ? 467 TRP B CE2 1 
ATOM 7671 C CE3 . TRP B 1 483 ? 152.232 176.864 214.967 1.00 24.80 ? 467 TRP B CE3 1 
ATOM 7672 C CZ2 . TRP B 1 483 ? 149.420 176.947 215.245 1.00 24.80 ? 467 TRP B CZ2 1 
ATOM 7673 C CZ3 . TRP B 1 483 ? 151.587 176.182 215.981 1.00 24.80 ? 467 TRP B CZ3 1 
ATOM 7674 C CH2 . TRP B 1 483 ? 150.195 176.228 216.112 1.00 24.80 ? 467 TRP B CH2 1 
ATOM 7675 N N   . LYS B 1 484 ? 156.045 179.996 213.359 1.00 18.61 ? 468 LYS B N   1 
ATOM 7676 C CA  . LYS B 1 484 ? 157.487 180.047 213.174 1.00 18.61 ? 468 LYS B CA  1 
ATOM 7677 C C   . LYS B 1 484 ? 158.095 178.712 213.576 1.00 18.61 ? 468 LYS B C   1 
ATOM 7678 O O   . LYS B 1 484 ? 157.676 178.102 214.565 1.00 18.61 ? 468 LYS B O   1 
ATOM 7679 C CB  . LYS B 1 484 ? 158.109 181.182 213.989 1.00 18.61 ? 468 LYS B CB  1 
ATOM 7680 C CG  . LYS B 1 484 ? 157.226 182.414 214.089 1.00 18.61 ? 468 LYS B CG  1 
ATOM 7681 C CD  . LYS B 1 484 ? 157.611 183.464 213.060 1.00 18.61 ? 468 LYS B CD  1 
ATOM 7682 C CE  . LYS B 1 484 ? 157.107 184.839 213.466 1.00 18.61 ? 468 LYS B CE  1 
ATOM 7683 N NZ  . LYS B 1 484 ? 157.410 185.870 212.437 1.00 18.61 ? 468 LYS B NZ  1 
ATOM 7684 N N   . ILE B 1 485 ? 159.081 178.262 212.805 1.00 11.94 ? 469 ILE B N   1 
ATOM 7685 C CA  . ILE B 1 485 ? 159.664 176.934 212.953 1.00 11.94 ? 469 ILE B CA  1 
ATOM 7686 C C   . ILE B 1 485 ? 161.163 177.074 213.187 1.00 11.94 ? 469 ILE B C   1 
ATOM 7687 O O   . ILE B 1 485 ? 161.840 177.832 212.482 1.00 11.94 ? 469 ILE B O   1 
ATOM 7688 C CB  . ILE B 1 485 ? 159.373 176.055 211.722 1.00 11.94 ? 469 ILE B CB  1 
ATOM 7689 C CG1 . ILE B 1 485 ? 160.104 174.719 211.823 1.00 11.94 ? 469 ILE B CG1 1 
ATOM 7690 C CG2 . ILE B 1 485 ? 159.741 176.782 210.436 1.00 11.94 ? 469 ILE B CG2 1 
ATOM 7691 C CD1 . ILE B 1 485 ? 159.849 173.809 210.651 1.00 11.94 ? 469 ILE B CD1 1 
ATOM 7692 N N   . ALA B 1 486 ? 161.673 176.357 214.187 1.00 11.09 ? 470 ALA B N   1 
ATOM 7693 C CA  . ALA B 1 486 ? 163.097 176.333 214.493 1.00 11.09 ? 470 ALA B CA  1 
ATOM 7694 C C   . ALA B 1 486 ? 163.523 174.893 214.728 1.00 11.09 ? 470 ALA B C   1 
ATOM 7695 O O   . ALA B 1 486 ? 162.837 174.152 215.437 1.00 11.09 ? 470 ALA B O   1 
ATOM 7696 C CB  . ALA B 1 486 ? 163.416 177.189 215.721 1.00 11.09 ? 470 ALA B CB  1 
ATOM 7697 N N   . SER B 1 487 ? 164.651 174.500 214.141 1.00 11.76 ? 471 SER B N   1 
ATOM 7698 C CA  . SER B 1 487 ? 165.145 173.131 214.220 1.00 11.76 ? 471 SER B CA  1 
ATOM 7699 C C   . SER B 1 487 ? 166.531 173.116 214.845 1.00 11.76 ? 471 SER B C   1 
ATOM 7700 O O   . SER B 1 487 ? 167.425 173.842 214.398 1.00 11.76 ? 471 SER B O   1 
ATOM 7701 C CB  . SER B 1 487 ? 165.185 172.483 212.834 1.00 11.76 ? 471 SER B CB  1 
ATOM 7702 O OG  . SER B 1 487 ? 165.924 173.277 211.924 1.00 11.76 ? 471 SER B OG  1 
ATOM 7703 N N   . CYS B 1 488 ? 166.709 172.283 215.869 1.00 16.18 ? 472 CYS B N   1 
ATOM 7704 C CA  . CYS B 1 488 ? 168.000 172.142 216.526 1.00 16.18 ? 472 CYS B CA  1 
ATOM 7705 C C   . CYS B 1 488 ? 168.071 170.776 217.192 1.00 16.18 ? 472 CYS B C   1 
ATOM 7706 O O   . CYS B 1 488 ? 167.054 170.256 217.658 1.00 16.18 ? 472 CYS B O   1 
ATOM 7707 C CB  . CYS B 1 488 ? 168.225 173.244 217.566 1.00 16.18 ? 472 CYS B CB  1 
ATOM 7708 S SG  . CYS B 1 488 ? 167.056 173.200 218.940 1.00 16.18 ? 472 CYS B SG  1 
ATOM 7709 N N   . ASN B 1 489 ? 169.278 170.208 217.231 1.00 20.05 ? 473 ASN B N   1 
ATOM 7710 C CA  . ASN B 1 489 ? 169.537 168.923 217.885 1.00 20.05 ? 473 ASN B CA  1 
ATOM 7711 C C   . ASN B 1 489 ? 168.646 167.815 217.326 1.00 20.05 ? 473 ASN B C   1 
ATOM 7712 O O   . ASN B 1 489 ? 168.227 166.908 218.047 1.00 20.05 ? 473 ASN B O   1 
ATOM 7713 C CB  . ASN B 1 489 ? 169.377 169.032 219.404 1.00 20.05 ? 473 ASN B CB  1 
ATOM 7714 C CG  . ASN B 1 489 ? 170.561 169.708 220.066 1.00 20.05 ? 473 ASN B CG  1 
ATOM 7715 O OD1 . ASN B 1 489 ? 171.357 170.376 219.407 1.00 20.05 ? 473 ASN B OD1 1 
ATOM 7716 N ND2 . ASN B 1 489 ? 170.686 169.532 221.376 1.00 20.05 ? 473 ASN B ND2 1 
ATOM 7717 N N   . GLY B 1 490 ? 168.360 167.888 216.030 1.00 17.27 ? 474 GLY B N   1 
ATOM 7718 C CA  . GLY B 1 490 ? 167.560 166.860 215.381 1.00 17.27 ? 474 GLY B CA  1 
ATOM 7719 C C   . GLY B 1 490 ? 166.153 166.731 215.920 1.00 17.27 ? 474 GLY B C   1 
ATOM 7720 O O   . GLY B 1 490 ? 165.652 165.611 216.082 1.00 17.27 ? 474 GLY B O   1 
ATOM 7721 N N   . SER B 1 491 ? 165.497 167.856 216.201 1.00 16.54 ? 475 SER B N   1 
ATOM 7722 C CA  . SER B 1 491 ? 164.132 167.828 216.722 1.00 16.54 ? 475 SER B CA  1 
ATOM 7723 C C   . SER B 1 491 ? 163.473 169.157 216.384 1.00 16.54 ? 475 SER B C   1 
ATOM 7724 O O   . SER B 1 491 ? 163.897 170.202 216.886 1.00 16.54 ? 475 SER B O   1 
ATOM 7725 C CB  . SER B 1 491 ? 164.129 167.574 218.224 1.00 16.54 ? 475 SER B CB  1 
ATOM 7726 O OG  . SER B 1 491 ? 164.060 168.791 218.943 1.00 16.54 ? 475 SER B OG  1 
ATOM 7727 N N   . ILE B 1 492 ? 162.443 169.112 215.540 1.00 11.97 ? 476 ILE B N   1 
ATOM 7728 C CA  . ILE B 1 492 ? 161.787 170.329 215.079 1.00 11.97 ? 476 ILE B CA  1 
ATOM 7729 C C   . ILE B 1 492 ? 161.013 170.965 216.226 1.00 11.97 ? 476 ILE B C   1 
ATOM 7730 O O   . ILE B 1 492 ? 160.298 170.282 216.970 1.00 11.97 ? 476 ILE B O   1 
ATOM 7731 C CB  . ILE B 1 492 ? 160.862 170.021 213.893 1.00 11.97 ? 476 ILE B CB  1 
ATOM 7732 C CG1 . ILE B 1 492 ? 161.573 169.123 212.882 1.00 11.97 ? 476 ILE B CG1 1 
ATOM 7733 C CG2 . ILE B 1 492 ? 160.406 171.305 213.233 1.00 11.97 ? 476 ILE B CG2 1 
ATOM 7734 C CD1 . ILE B 1 492 ? 162.761 169.776 212.222 1.00 11.97 ? 476 ILE B CD1 1 
ATOM 7735 N N   . TYR B 1 493 ? 161.156 172.279 216.372 1.00 16.56 ? 477 TYR B N   1 
ATOM 7736 C CA  . TYR B 1 493 ? 160.393 173.062 217.334 1.00 16.56 ? 477 TYR B CA  1 
ATOM 7737 C C   . TYR B 1 493 ? 159.525 174.060 216.583 1.00 16.56 ? 477 TYR B C   1 
ATOM 7738 O O   . TYR B 1 493 ? 160.023 174.796 215.724 1.00 16.56 ? 477 TYR B O   1 
ATOM 7739 C CB  . TYR B 1 493 ? 161.316 173.797 218.307 1.00 16.56 ? 477 TYR B CB  1 
ATOM 7740 C CG  . TYR B 1 493 ? 161.749 172.974 219.497 1.00 16.56 ? 477 TYR B CG  1 
ATOM 7741 C CD1 . TYR B 1 493 ? 162.765 172.036 219.385 1.00 16.56 ? 477 TYR B CD1 1 
ATOM 7742 C CD2 . TYR B 1 493 ? 161.144 173.139 220.735 1.00 16.56 ? 477 TYR B CD2 1 
ATOM 7743 C CE1 . TYR B 1 493 ? 163.164 171.285 220.472 1.00 16.56 ? 477 TYR B CE1 1 
ATOM 7744 C CE2 . TYR B 1 493 ? 161.537 172.392 221.827 1.00 16.56 ? 477 TYR B CE2 1 
ATOM 7745 C CZ  . TYR B 1 493 ? 162.547 171.466 221.690 1.00 16.56 ? 477 TYR B CZ  1 
ATOM 7746 O OH  . TYR B 1 493 ? 162.944 170.718 222.774 1.00 16.56 ? 477 TYR B OH  1 
ATOM 7747 N N   . VAL B 1 494 ? 158.236 174.085 216.905 1.00 18.25 ? 478 VAL B N   1 
ATOM 7748 C CA  . VAL B 1 494 ? 157.278 174.988 216.276 1.00 18.25 ? 478 VAL B CA  1 
ATOM 7749 C C   . VAL B 1 494 ? 156.693 175.878 217.363 1.00 18.25 ? 478 VAL B C   1 
ATOM 7750 O O   . VAL B 1 494 ? 156.203 175.378 218.383 1.00 18.25 ? 478 VAL B O   1 
ATOM 7751 C CB  . VAL B 1 494 ? 156.173 174.222 215.534 1.00 18.25 ? 478 VAL B CB  1 
ATOM 7752 C CG1 . VAL B 1 494 ? 155.271 175.188 214.795 1.00 18.25 ? 478 VAL B CG1 1 
ATOM 7753 C CG2 . VAL B 1 494 ? 156.781 173.220 214.572 1.00 18.25 ? 478 VAL B CG2 1 
ATOM 7754 N N   . PHE B 1 495 ? 156.742 177.189 217.145 1.00 19.60 ? 479 PHE B N   1 
ATOM 7755 C CA  . PHE B 1 495 ? 156.314 178.172 218.131 1.00 19.60 ? 479 PHE B CA  1 
ATOM 7756 C C   . PHE B 1 495 ? 155.070 178.897 217.636 1.00 19.60 ? 479 PHE B C   1 
ATOM 7757 O O   . PHE B 1 495 ? 155.052 179.416 216.515 1.00 19.60 ? 479 PHE B O   1 
ATOM 7758 C CB  . PHE B 1 495 ? 157.432 179.176 218.416 1.00 19.60 ? 479 PHE B CB  1 
ATOM 7759 C CG  . PHE B 1 495 ? 158.579 178.601 219.195 1.00 19.60 ? 479 PHE B CG  1 
ATOM 7760 C CD1 . PHE B 1 495 ? 158.360 177.641 220.167 1.00 19.60 ? 479 PHE B CD1 1 
ATOM 7761 C CD2 . PHE B 1 495 ? 159.876 179.016 218.951 1.00 19.60 ? 479 PHE B CD2 1 
ATOM 7762 C CE1 . PHE B 1 495 ? 159.413 177.109 220.885 1.00 19.60 ? 479 PHE B CE1 1 
ATOM 7763 C CE2 . PHE B 1 495 ? 160.933 178.488 219.665 1.00 19.60 ? 479 PHE B CE2 1 
ATOM 7764 C CZ  . PHE B 1 495 ? 160.701 177.533 220.633 1.00 19.60 ? 479 PHE B CZ  1 
ATOM 7765 N N   . ARG B 1 496 ? 154.036 178.929 218.474 1.00 29.26 ? 480 ARG B N   1 
ATOM 7766 C CA  . ARG B 1 496 ? 152.811 179.639 218.143 1.00 29.26 ? 480 ARG B CA  1 
ATOM 7767 C C   . ARG B 1 496 ? 152.915 181.104 218.566 1.00 29.26 ? 480 ARG B C   1 
ATOM 7768 O O   . ARG B 1 496 ? 153.501 181.443 219.597 1.00 29.26 ? 480 ARG B O   1 
ATOM 7769 C CB  . ARG B 1 496 ? 151.611 178.963 218.810 1.00 29.26 ? 480 ARG B CB  1 
ATOM 7770 C CG  . ARG B 1 496 ? 150.436 179.882 219.110 1.00 29.26 ? 480 ARG B CG  1 
ATOM 7771 C CD  . ARG B 1 496 ? 149.229 179.099 219.599 1.00 29.26 ? 480 ARG B CD  1 
ATOM 7772 N NE  . ARG B 1 496 ? 148.518 178.437 218.512 1.00 29.26 ? 480 ARG B NE  1 
ATOM 7773 C CZ  . ARG B 1 496 ? 147.585 179.016 217.769 1.00 29.26 ? 480 ARG B CZ  1 
ATOM 7774 N NH1 . ARG B 1 496 ? 147.230 180.276 217.962 1.00 29.26 ? 480 ARG B NH1 1 
ATOM 7775 N NH2 . ARG B 1 496 ? 146.991 178.313 216.809 1.00 29.26 ? 480 ARG B NH2 1 
ATOM 7776 N N   . ASP B 1 497 ? 152.331 181.979 217.748 1.00 25.49 ? 481 ASP B N   1 
ATOM 7777 C CA  . ASP B 1 497 ? 152.433 183.416 217.947 1.00 25.49 ? 481 ASP B CA  1 
ATOM 7778 C C   . ASP B 1 497 ? 151.063 183.994 218.270 1.00 25.49 ? 481 ASP B C   1 
ATOM 7779 O O   . ASP B 1 497 ? 150.042 183.506 217.777 1.00 25.49 ? 481 ASP B O   1 
ATOM 7780 C CB  . ASP B 1 497 ? 153.009 184.105 216.700 1.00 25.49 ? 481 ASP B CB  1 
ATOM 7781 C CG  . ASP B 1 497 ? 153.258 185.589 216.908 1.00 25.49 ? 481 ASP B CG  1 
ATOM 7782 O OD1 . ASP B 1 497 ? 153.137 186.067 218.056 1.00 25.49 ? 481 ASP B OD1 1 
ATOM 7783 O OD2 . ASP B 1 497 ? 153.574 186.280 215.917 1.00 25.49 ? 481 ASP B OD2 1 
ATOM 7784 N N   . ARG B 1 498 ? 151.057 185.033 219.104 1.00 30.14 ? 482 ARG B N   1 
ATOM 7785 C CA  . ARG B 1 498 ? 149.864 185.821 219.413 1.00 30.14 ? 482 ARG B CA  1 
ATOM 7786 C C   . ARG B 1 498 ? 148.757 184.958 220.021 1.00 30.14 ? 482 ARG B C   1 
ATOM 7787 O O   . ARG B 1 498 ? 147.677 184.785 219.452 1.00 30.14 ? 482 ARG B O   1 
ATOM 7788 C CB  . ARG B 1 498 ? 149.364 186.559 218.168 1.00 30.14 ? 482 ARG B CB  1 
ATOM 7789 C CG  . ARG B 1 498 ? 150.171 187.797 217.813 1.00 30.14 ? 482 ARG B CG  1 
ATOM 7790 C CD  . ARG B 1 498 ? 150.179 188.800 218.955 1.00 30.14 ? 482 ARG B CD  1 
ATOM 7791 N NE  . ARG B 1 498 ? 148.846 189.012 219.507 1.00 30.14 ? 482 ARG B NE  1 
ATOM 7792 C CZ  . ARG B 1 498 ? 148.012 189.962 219.106 1.00 30.14 ? 482 ARG B CZ  1 
ATOM 7793 N NH1 . ARG B 1 498 ? 148.340 190.810 218.144 1.00 30.14 ? 482 ARG B NH1 1 
ATOM 7794 N NH2 . ARG B 1 498 ? 146.818 190.064 219.683 1.00 30.14 ? 482 ARG B NH2 1 
ATOM 7795 N N   . TYR B 1 499 ? 149.045 184.414 221.198 1.00 30.95 ? 483 TYR B N   1 
ATOM 7796 C CA  . TYR B 1 499 ? 148.048 183.679 221.962 1.00 30.95 ? 483 TYR B CA  1 
ATOM 7797 C C   . TYR B 1 499 ? 147.171 184.645 222.751 1.00 30.95 ? 483 TYR B C   1 
ATOM 7798 O O   . TYR B 1 499 ? 147.579 185.764 223.073 1.00 30.95 ? 483 TYR B O   1 
ATOM 7799 C CB  . TYR B 1 499 ? 148.710 182.680 222.911 1.00 30.95 ? 483 TYR B CB  1 
ATOM 7800 C CG  . TYR B 1 499 ? 147.817 181.516 223.280 1.00 30.95 ? 483 TYR B CG  1 
ATOM 7801 C CD1 . TYR B 1 499 ? 147.733 180.396 222.465 1.00 30.95 ? 483 TYR B CD1 1 
ATOM 7802 C CD2 . TYR B 1 499 ? 147.058 181.537 224.442 1.00 30.95 ? 483 TYR B CD2 1 
ATOM 7803 C CE1 . TYR B 1 499 ? 146.920 179.329 222.796 1.00 30.95 ? 483 TYR B CE1 1 
ATOM 7804 C CE2 . TYR B 1 499 ? 146.241 180.475 224.782 1.00 30.95 ? 483 TYR B CE2 1 
ATOM 7805 C CZ  . TYR B 1 499 ? 146.176 179.373 223.955 1.00 30.95 ? 483 TYR B CZ  1 
ATOM 7806 O OH  . TYR B 1 499 ? 145.365 178.313 224.289 1.00 30.95 ? 483 TYR B OH  1 
ATOM 7807 N N   . LYS B 1 500 ? 145.955 184.198 223.059 1.00 26.08 ? 484 LYS B N   1 
ATOM 7808 C CA  . LYS B 1 500 ? 144.974 185.033 223.751 1.00 26.08 ? 484 LYS B CA  1 
ATOM 7809 C C   . LYS B 1 500 ? 145.113 184.892 225.269 1.00 26.08 ? 484 LYS B C   1 
ATOM 7810 O O   . LYS B 1 500 ? 144.220 184.410 225.967 1.00 26.08 ? 484 LYS B O   1 
ATOM 7811 C CB  . LYS B 1 500 ? 143.565 184.683 223.286 1.00 26.08 ? 484 LYS B CB  1 
ATOM 7812 C CG  . LYS B 1 500 ? 142.526 185.756 223.576 1.00 26.08 ? 484 LYS B CG  1 
ATOM 7813 C CD  . LYS B 1 500 ? 142.989 187.120 223.090 1.00 26.08 ? 484 LYS B CD  1 
ATOM 7814 C CE  . LYS B 1 500 ? 142.170 188.235 223.718 1.00 26.08 ? 484 LYS B CE  1 
ATOM 7815 N NZ  . LYS B 1 500 ? 142.264 188.224 225.204 1.00 26.08 ? 484 LYS B NZ  1 
ATOM 7816 N N   . LYS B 1 501 ? 146.266 185.333 225.770 1.00 23.94 ? 485 LYS B N   1 
ATOM 7817 C CA  . LYS B 1 501 ? 146.558 185.381 227.203 1.00 23.94 ? 485 LYS B CA  1 
ATOM 7818 C C   . LYS B 1 501 ? 146.371 184.007 227.851 1.00 23.94 ? 485 LYS B C   1 
ATOM 7819 O O   . LYS B 1 501 ? 145.497 183.790 228.692 1.00 23.94 ? 485 LYS B O   1 
ATOM 7820 C CB  . LYS B 1 501 ? 145.700 186.446 227.895 1.00 23.94 ? 485 LYS B CB  1 
ATOM 7821 C CG  . LYS B 1 501 ? 146.117 186.762 229.325 1.00 23.94 ? 485 LYS B CG  1 
ATOM 7822 C CD  . LYS B 1 501 ? 147.545 187.279 229.385 1.00 23.94 ? 485 LYS B CD  1 
ATOM 7823 C CE  . LYS B 1 501 ? 147.987 187.506 230.822 1.00 23.94 ? 485 LYS B CE  1 
ATOM 7824 N NZ  . LYS B 1 501 ? 147.837 186.277 231.650 1.00 23.94 ? 485 LYS B NZ  1 
ATOM 7825 N N   . GLY B 1 502 ? 147.210 183.066 227.426 1.00 22.53 ? 486 GLY B N   1 
ATOM 7826 C CA  . GLY B 1 502 ? 147.145 181.718 227.953 1.00 22.53 ? 486 GLY B CA  1 
ATOM 7827 C C   . GLY B 1 502 ? 148.498 181.056 228.101 1.00 22.53 ? 486 GLY B C   1 
ATOM 7828 O O   . GLY B 1 502 ? 149.528 181.734 228.169 1.00 22.53 ? 486 GLY B O   1 
ATOM 7829 N N   . ASP B 1 503 ? 148.506 179.726 228.155 1.00 25.66 ? 487 ASP B N   1 
ATOM 7830 C CA  . ASP B 1 503 ? 149.750 178.989 228.328 1.00 25.66 ? 487 ASP B CA  1 
ATOM 7831 C C   . ASP B 1 503 ? 150.623 179.102 227.084 1.00 25.66 ? 487 ASP B C   1 
ATOM 7832 O O   . ASP B 1 503 ? 150.126 179.156 225.956 1.00 25.66 ? 487 ASP B O   1 
ATOM 7833 C CB  . ASP B 1 503 ? 149.454 177.520 228.632 1.00 25.66 ? 487 ASP B CB  1 
ATOM 7834 C CG  . ASP B 1 503 ? 148.718 176.827 227.503 1.00 25.66 ? 487 ASP B CG  1 
ATOM 7835 O OD1 . ASP B 1 503 ? 147.761 177.421 226.964 1.00 25.66 ? 487 ASP B OD1 1 
ATOM 7836 O OD2 . ASP B 1 503 ? 149.097 175.690 227.153 1.00 25.66 ? 487 ASP B OD2 1 
ATOM 7837 N N   . ALA B 1 504 ? 151.935 179.141 227.300 1.00 21.77 ? 488 ALA B N   1 
ATOM 7838 C CA  . ALA B 1 504 ? 152.878 179.199 226.194 1.00 21.77 ? 488 ALA B CA  1 
ATOM 7839 C C   . ALA B 1 504 ? 152.847 177.901 225.395 1.00 21.77 ? 488 ALA B C   1 
ATOM 7840 O O   . ALA B 1 504 ? 152.551 176.825 225.922 1.00 21.77 ? 488 ALA B O   1 
ATOM 7841 C CB  . ALA B 1 504 ? 154.293 179.464 226.709 1.00 21.77 ? 488 ALA B CB  1 
ATOM 7842 N N   . ASN B 1 505 ? 153.153 178.012 224.104 1.00 24.43 ? 489 ASN B N   1 
ATOM 7843 C CA  . ASN B 1 505 ? 153.118 176.881 223.186 1.00 24.43 ? 489 ASN B CA  1 
ATOM 7844 C C   . ASN B 1 505 ? 154.512 176.654 222.621 1.00 24.43 ? 489 ASN B C   1 
ATOM 7845 O O   . ASN B 1 505 ? 155.029 177.494 221.876 1.00 24.43 ? 489 ASN B O   1 
ATOM 7846 C CB  . ASN B 1 505 ? 152.109 177.125 222.063 1.00 24.43 ? 489 ASN B CB  1 
ATOM 7847 C CG  . ASN B 1 505 ? 150.755 177.554 222.587 1.00 24.43 ? 489 ASN B CG  1 
ATOM 7848 O OD1 . ASN B 1 505 ? 149.937 176.724 222.985 1.00 24.43 ? 489 ASN B OD1 1 
ATOM 7849 N ND2 . ASN B 1 505 ? 150.517 178.859 222.608 1.00 24.43 ? 489 ASN B ND2 1 
ATOM 7850 N N   . THR B 1 506 ? 155.113 175.522 222.978 1.00 22.84 ? 490 THR B N   1 
ATOM 7851 C CA  . THR B 1 506 ? 156.441 175.134 222.509 1.00 22.84 ? 490 THR B CA  1 
ATOM 7852 C C   . THR B 1 506 ? 156.382 173.721 221.939 1.00 22.84 ? 490 THR B C   1 
ATOM 7853 O O   . THR B 1 506 ? 157.169 172.845 222.300 1.00 22.84 ? 490 THR B O   1 
ATOM 7854 C CB  . THR B 1 506 ? 157.484 175.220 223.624 1.00 22.84 ? 490 THR B CB  1 
ATOM 7855 O OG1 . THR B 1 506 ? 157.532 173.974 224.331 1.00 22.84 ? 490 THR B OG1 1 
ATOM 7856 C CG2 . THR B 1 506 ? 157.155 176.341 224.602 1.00 22.84 ? 490 THR B CG2 1 
ATOM 7857 N N   . TYR B 1 507 ? 155.419 173.488 221.047 1.00 23.61 ? 491 TYR B N   1 
ATOM 7858 C CA  . TYR B 1 507 ? 155.184 172.155 220.511 1.00 23.61 ? 491 TYR B CA  1 
ATOM 7859 C C   . TYR B 1 507 ? 156.437 171.589 219.851 1.00 23.61 ? 491 TYR B C   1 
ATOM 7860 O O   . TYR B 1 507 ? 157.124 172.266 219.082 1.00 23.61 ? 491 TYR B O   1 
ATOM 7861 C CB  . TYR B 1 507 ? 154.042 172.182 219.494 1.00 23.61 ? 491 TYR B CB  1 
ATOM 7862 C CG  . TYR B 1 507 ? 152.769 172.821 219.996 1.00 23.61 ? 491 TYR B CG  1 
ATOM 7863 C CD1 . TYR B 1 507 ? 152.093 172.299 221.091 1.00 23.61 ? 491 TYR B CD1 1 
ATOM 7864 C CD2 . TYR B 1 507 ? 152.239 173.940 219.371 1.00 23.61 ? 491 TYR B CD2 1 
ATOM 7865 C CE1 . TYR B 1 507 ? 150.925 172.878 221.551 1.00 23.61 ? 491 TYR B CE1 1 
ATOM 7866 C CE2 . TYR B 1 507 ? 151.072 174.526 219.824 1.00 23.61 ? 491 TYR B CE2 1 
ATOM 7867 C CZ  . TYR B 1 507 ? 150.420 173.991 220.914 1.00 23.61 ? 491 TYR B CZ  1 
ATOM 7868 O OH  . TYR B 1 507 ? 149.258 174.571 221.370 1.00 23.61 ? 491 TYR B OH  1 
ATOM 7869 N N   . LYS B 1 508 ? 156.727 170.330 220.164 1.00 17.69 ? 492 LYS B N   1 
ATOM 7870 C CA  . LYS B 1 508 ? 157.789 169.574 219.520 1.00 17.69 ? 492 LYS B CA  1 
ATOM 7871 C C   . LYS B 1 508 ? 157.193 168.782 218.365 1.00 17.69 ? 492 LYS B C   1 
ATOM 7872 O O   . LYS B 1 508 ? 156.111 168.202 218.493 1.00 17.69 ? 492 LYS B O   1 
ATOM 7873 C CB  . LYS B 1 508 ? 158.482 168.635 220.512 1.00 17.69 ? 492 LYS B CB  1 
ATOM 7874 C CG  . LYS B 1 508 ? 159.319 167.544 219.864 1.00 17.69 ? 492 LYS B CG  1 
ATOM 7875 C CD  . LYS B 1 508 ? 160.276 166.909 220.861 1.00 17.69 ? 492 LYS B CD  1 
ATOM 7876 C CE  . LYS B 1 508 ? 161.055 167.962 221.633 1.00 17.69 ? 492 LYS B CE  1 
ATOM 7877 N NZ  . LYS B 1 508 ? 161.581 167.432 222.921 1.00 17.69 ? 492 LYS B NZ  1 
ATOM 7878 N N   . LEU B 1 509 ? 157.898 168.764 217.240 1.00 10.92 ? 493 LEU B N   1 
ATOM 7879 C CA  . LEU B 1 509 ? 157.371 168.251 215.981 1.00 10.92 ? 493 LEU B CA  1 
ATOM 7880 C C   . LEU B 1 509 ? 158.296 167.186 215.410 1.00 10.92 ? 493 LEU B C   1 
ATOM 7881 O O   . LEU B 1 509 ? 158.741 167.264 214.262 1.00 10.92 ? 493 LEU B O   1 
ATOM 7882 C CB  . LEU B 1 509 ? 157.155 169.391 214.991 1.00 10.92 ? 493 LEU B CB  1 
ATOM 7883 C CG  . LEU B 1 509 ? 156.291 169.113 213.760 1.00 10.92 ? 493 LEU B CG  1 
ATOM 7884 C CD1 . LEU B 1 509 ? 154.820 169.305 214.078 1.00 10.92 ? 493 LEU B CD1 1 
ATOM 7885 C CD2 . LEU B 1 509 ? 156.715 170.024 212.627 1.00 10.92 ? 493 LEU B CD2 1 
ATOM 7886 N N   . ASP B 1 510 ? 158.638 166.192 216.239 1.00 10.22 ? 494 ASP B N   1 
ATOM 7887 C CA  . ASP B 1 510 ? 159.430 165.041 215.816 1.00 10.22 ? 494 ASP B CA  1 
ATOM 7888 C C   . ASP B 1 510 ? 158.876 164.488 214.509 1.00 10.22 ? 494 ASP B C   1 
ATOM 7889 O O   . ASP B 1 510 ? 157.766 163.943 214.480 1.00 10.22 ? 494 ASP B O   1 
ATOM 7890 C CB  . ASP B 1 510 ? 159.434 163.959 216.897 1.00 10.22 ? 494 ASP B CB  1 
ATOM 7891 C CG  . ASP B 1 510 ? 160.018 162.649 216.407 1.00 10.22 ? 494 ASP B CG  1 
ATOM 7892 O OD1 . ASP B 1 510 ? 161.203 162.636 216.014 1.00 10.22 ? 494 ASP B OD1 1 
ATOM 7893 O OD2 . ASP B 1 510 ? 159.293 161.633 216.416 1.00 10.22 ? 494 ASP B OD2 1 
ATOM 7894 N N   . PRO B 1 511 ? 159.619 164.614 213.406 1.00 7.50  ? 495 PRO B N   1 
ATOM 7895 C CA  . PRO B 1 511 ? 159.032 164.368 212.081 1.00 7.50  ? 495 PRO B CA  1 
ATOM 7896 C C   . PRO B 1 511 ? 158.876 162.903 211.708 1.00 7.50  ? 495 PRO B C   1 
ATOM 7897 O O   . PRO B 1 511 ? 158.287 162.620 210.656 1.00 7.50  ? 495 PRO B O   1 
ATOM 7898 C CB  . PRO B 1 511 ? 160.016 165.067 211.138 1.00 7.50  ? 495 PRO B CB  1 
ATOM 7899 C CG  . PRO B 1 511 ? 161.314 165.022 211.866 1.00 7.50  ? 495 PRO B CG  1 
ATOM 7900 C CD  . PRO B 1 511 ? 160.989 165.146 213.321 1.00 7.50  ? 495 PRO B CD  1 
ATOM 7901 N N   . ALA B 1 512 ? 159.383 161.967 212.513 1.00 10.07 ? 496 ALA B N   1 
ATOM 7902 C CA  . ALA B 1 512 ? 159.199 160.553 212.198 1.00 10.07 ? 496 ALA B CA  1 
ATOM 7903 C C   . ALA B 1 512 ? 157.723 160.177 212.233 1.00 10.07 ? 496 ALA B C   1 
ATOM 7904 O O   . ALA B 1 512 ? 157.193 159.597 211.278 1.00 10.07 ? 496 ALA B O   1 
ATOM 7905 C CB  . ALA B 1 512 ? 160.002 159.689 213.170 1.00 10.07 ? 496 ALA B CB  1 
ATOM 7906 N N   . THR B 1 513 ? 157.045 160.500 213.331 1.00 12.56 ? 497 THR B N   1 
ATOM 7907 C CA  . THR B 1 513 ? 155.602 160.348 213.446 1.00 12.56 ? 497 THR B CA  1 
ATOM 7908 C C   . THR B 1 513 ? 155.053 161.605 214.103 1.00 12.56 ? 497 THR B C   1 
ATOM 7909 O O   . THR B 1 513 ? 155.715 162.197 214.959 1.00 12.56 ? 497 THR B O   1 
ATOM 7910 C CB  . THR B 1 513 ? 155.212 159.112 214.269 1.00 12.56 ? 497 THR B CB  1 
ATOM 7911 O OG1 . THR B 1 513 ? 155.724 159.242 215.601 1.00 12.56 ? 497 THR B OG1 1 
ATOM 7912 C CG2 . THR B 1 513 ? 155.760 157.839 213.638 1.00 12.56 ? 497 THR B CG2 1 
ATOM 7913 N N   . SER B 1 514 ? 153.844 162.004 213.709 1.00 14.23 ? 498 SER B N   1 
ATOM 7914 C CA  . SER B 1 514 ? 153.255 163.217 214.262 1.00 14.23 ? 498 SER B CA  1 
ATOM 7915 C C   . SER B 1 514 ? 153.024 163.047 215.758 1.00 14.23 ? 498 SER B C   1 
ATOM 7916 O O   . SER B 1 514 ? 152.095 162.350 216.178 1.00 14.23 ? 498 SER B O   1 
ATOM 7917 C CB  . SER B 1 514 ? 151.946 163.558 213.547 1.00 14.23 ? 498 SER B CB  1 
ATOM 7918 O OG  . SER B 1 514 ? 152.169 164.470 212.486 1.00 14.23 ? 498 SER B OG  1 
ATOM 7919 N N   . ALA B 1 515 ? 153.869 163.684 216.563 1.00 17.57 ? 499 ALA B N   1 
ATOM 7920 C CA  . ALA B 1 515 ? 153.905 163.498 218.010 1.00 17.57 ? 499 ALA B CA  1 
ATOM 7921 C C   . ALA B 1 515 ? 154.005 164.841 218.719 1.00 17.57 ? 499 ALA B C   1 
ATOM 7922 O O   . ALA B 1 515 ? 154.884 165.066 219.553 1.00 17.57 ? 499 ALA B O   1 
ATOM 7923 C CB  . ALA B 1 515 ? 155.061 162.587 218.411 1.00 17.57 ? 499 ALA B CB  1 
ATOM 7924 N N   . VAL B 1 516 ? 153.117 165.769 218.369 1.00 17.80 ? 500 VAL B N   1 
ATOM 7925 C CA  . VAL B 1 516 ? 153.118 167.093 218.983 1.00 17.80 ? 500 VAL B CA  1 
ATOM 7926 C C   . VAL B 1 516 ? 152.788 166.988 220.469 1.00 17.80 ? 500 VAL B C   1 
ATOM 7927 O O   . VAL B 1 516 ? 151.679 166.600 220.854 1.00 17.80 ? 500 VAL B O   1 
ATOM 7928 C CB  . VAL B 1 516 ? 152.153 168.044 218.247 1.00 17.80 ? 500 VAL B CB  1 
ATOM 7929 C CG1 . VAL B 1 516 ? 152.687 168.353 216.863 1.00 17.80 ? 500 VAL B CG1 1 
ATOM 7930 C CG2 . VAL B 1 516 ? 150.765 167.427 218.122 1.00 17.80 ? 500 VAL B CG2 1 
ATOM 7931 N N   . THR B 1 517 ? 153.766 167.308 221.317 1.00 22.41 ? 501 THR B N   1 
ATOM 7932 C CA  . THR B 1 517 ? 153.588 167.328 222.764 1.00 22.41 ? 501 THR B CA  1 
ATOM 7933 C C   . THR B 1 517 ? 154.080 168.660 223.307 1.00 22.41 ? 501 THR B C   1 
ATOM 7934 O O   . THR B 1 517 ? 155.123 169.161 222.877 1.00 22.41 ? 501 THR B O   1 
ATOM 7935 C CB  . THR B 1 517 ? 154.339 166.182 223.459 1.00 22.41 ? 501 THR B CB  1 
ATOM 7936 O OG1 . THR B 1 517 ? 155.687 166.587 223.735 1.00 22.41 ? 501 THR B OG1 1 
ATOM 7937 C CG2 . THR B 1 517 ? 154.347 164.923 222.608 1.00 22.41 ? 501 THR B CG2 1 
ATOM 7938 N N   . VAL B 1 518 ? 153.330 169.226 224.252 1.00 23.29 ? 502 VAL B N   1 
ATOM 7939 C CA  . VAL B 1 518 ? 153.741 170.470 224.889 1.00 23.29 ? 502 VAL B CA  1 
ATOM 7940 C C   . VAL B 1 518 ? 154.864 170.184 225.876 1.00 23.29 ? 502 VAL B C   1 
ATOM 7941 O O   . VAL B 1 518 ? 154.761 169.281 226.716 1.00 23.29 ? 502 VAL B O   1 
ATOM 7942 C CB  . VAL B 1 518 ? 152.546 171.139 225.585 1.00 23.29 ? 502 VAL B CB  1 
ATOM 7943 C CG1 . VAL B 1 518 ? 152.921 172.536 226.056 1.00 23.29 ? 502 VAL B CG1 1 
ATOM 7944 C CG2 . VAL B 1 518 ? 151.347 171.184 224.652 1.00 23.29 ? 502 VAL B CG2 1 
ATOM 7945 N N   . THR B 1 519 ? 155.944 170.955 225.779 1.00 22.04 ? 503 THR B N   1 
ATOM 7946 C CA  . THR B 1 519 ? 157.077 170.811 226.679 1.00 22.04 ? 503 THR B CA  1 
ATOM 7947 C C   . THR B 1 519 ? 156.815 171.601 227.961 1.00 22.04 ? 503 THR B C   1 
ATOM 7948 O O   . THR B 1 519 ? 155.692 172.036 228.229 1.00 22.04 ? 503 THR B O   1 
ATOM 7949 C CB  . THR B 1 519 ? 158.366 171.256 225.990 1.00 22.04 ? 503 THR B CB  1 
ATOM 7950 O OG1 . THR B 1 519 ? 158.474 172.683 226.047 1.00 22.04 ? 503 THR B OG1 1 
ATOM 7951 C CG2 . THR B 1 519 ? 158.376 170.806 224.537 1.00 22.04 ? 503 THR B CG2 1 
ATOM 7952 N N   . ARG B 1 520 ? 157.854 171.781 228.774 1.00 22.82 ? 504 ARG B N   1 
ATOM 7953 C CA  . ARG B 1 520 ? 157.706 172.502 230.031 1.00 22.82 ? 504 ARG B CA  1 
ATOM 7954 C C   . ARG B 1 520 ? 157.278 173.943 229.781 1.00 22.82 ? 504 ARG B C   1 
ATOM 7955 O O   . ARG B 1 520 ? 157.726 174.588 228.829 1.00 22.82 ? 504 ARG B O   1 
ATOM 7956 C CB  . ARG B 1 520 ? 159.016 172.473 230.818 1.00 22.82 ? 504 ARG B CB  1 
ATOM 7957 C CG  . ARG B 1 520 ? 159.585 171.081 231.027 1.00 22.82 ? 504 ARG B CG  1 
ATOM 7958 C CD  . ARG B 1 520 ? 160.826 171.125 231.902 1.00 22.82 ? 504 ARG B CD  1 
ATOM 7959 N NE  . ARG B 1 520 ? 160.621 171.938 233.095 1.00 22.82 ? 504 ARG B NE  1 
ATOM 7960 C CZ  . ARG B 1 520 ? 160.019 171.514 234.198 1.00 22.82 ? 504 ARG B CZ  1 
ATOM 7961 N NH1 . ARG B 1 520 ? 159.549 170.281 234.298 1.00 22.82 ? 504 ARG B NH1 1 
ATOM 7962 N NH2 . ARG B 1 520 ? 159.885 172.347 235.225 1.00 22.82 ? 504 ARG B NH2 1 
ATOM 7963 N N   . GLY B 1 521 ? 156.403 174.445 230.648 1.00 20.88 ? 505 GLY B N   1 
ATOM 7964 C CA  . GLY B 1 521 ? 155.890 175.793 230.514 1.00 20.88 ? 505 GLY B CA  1 
ATOM 7965 C C   . GLY B 1 521 ? 156.830 176.848 231.057 1.00 20.88 ? 505 GLY B C   1 
ATOM 7966 O O   . GLY B 1 521 ? 156.595 177.405 232.134 1.00 20.88 ? 505 GLY B O   1 
ATOM 7967 N N   . ILE B 1 522 ? 157.907 177.124 230.320 1.00 20.44 ? 506 ILE B N   1 
ATOM 7968 C CA  . ILE B 1 522 ? 158.851 178.157 230.725 1.00 20.44 ? 506 ILE B CA  1 
ATOM 7969 C C   . ILE B 1 522 ? 158.167 179.516 230.693 1.00 20.44 ? 506 ILE B C   1 
ATOM 7970 O O   . ILE B 1 522 ? 157.359 179.807 229.800 1.00 20.44 ? 506 ILE B O   1 
ATOM 7971 C CB  . ILE B 1 522 ? 160.093 178.134 229.819 1.00 20.44 ? 506 ILE B CB  1 
ATOM 7972 C CG1 . ILE B 1 522 ? 159.678 178.036 228.349 1.00 20.44 ? 506 ILE B CG1 1 
ATOM 7973 C CG2 . ILE B 1 522 ? 161.009 176.980 230.200 1.00 20.44 ? 506 ILE B CG2 1 
ATOM 7974 C CD1 . ILE B 1 522 ? 160.837 177.846 227.395 1.00 20.44 ? 506 ILE B CD1 1 
ATOM 7975 N N   . LYS B 1 523 ? 158.486 180.359 231.676 1.00 18.69 ? 507 LYS B N   1 
ATOM 7976 C CA  . LYS B 1 523 ? 157.847 181.667 231.818 1.00 18.69 ? 507 LYS B CA  1 
ATOM 7977 C C   . LYS B 1 523 ? 158.527 182.677 230.891 1.00 18.69 ? 507 LYS B C   1 
ATOM 7978 O O   . LYS B 1 523 ? 159.193 183.624 231.315 1.00 18.69 ? 507 LYS B O   1 
ATOM 7979 C CB  . LYS B 1 523 ? 157.887 182.125 233.269 1.00 18.69 ? 507 LYS B CB  1 
ATOM 7980 C CG  . LYS B 1 523 ? 157.414 181.078 234.264 1.00 18.69 ? 507 LYS B CG  1 
ATOM 7981 C CD  . LYS B 1 523 ? 157.694 181.511 235.694 1.00 18.69 ? 507 LYS B CD  1 
ATOM 7982 C CE  . LYS B 1 523 ? 157.031 180.577 236.694 1.00 18.69 ? 507 LYS B CE  1 
ATOM 7983 N NZ  . LYS B 1 523 ? 157.226 181.037 238.097 1.00 18.69 ? 507 LYS B NZ  1 
ATOM 7984 N N   . VAL B 1 524 ? 158.345 182.453 229.588 1.00 19.32 ? 508 VAL B N   1 
ATOM 7985 C CA  . VAL B 1 524 ? 158.855 183.398 228.600 1.00 19.32 ? 508 VAL B CA  1 
ATOM 7986 C C   . VAL B 1 524 ? 158.057 184.696 228.645 1.00 19.32 ? 508 VAL B C   1 
ATOM 7987 O O   . VAL B 1 524 ? 158.625 185.792 228.553 1.00 19.32 ? 508 VAL B O   1 
ATOM 7988 C CB  . VAL B 1 524 ? 158.848 182.765 227.197 1.00 19.32 ? 508 VAL B CB  1 
ATOM 7989 C CG1 . VAL B 1 524 ? 159.973 181.750 227.071 1.00 19.32 ? 508 VAL B CG1 1 
ATOM 7990 C CG2 . VAL B 1 524 ? 157.507 182.104 226.911 1.00 19.32 ? 508 VAL B CG2 1 
ATOM 7991 N N   . LEU B 1 525 ? 156.734 184.593 228.791 1.00 18.93 ? 509 LEU B N   1 
ATOM 7992 C CA  . LEU B 1 525 ? 155.852 185.751 228.961 1.00 18.93 ? 509 LEU B CA  1 
ATOM 7993 C C   . LEU B 1 525 ? 155.999 186.747 227.813 1.00 18.93 ? 509 LEU B C   1 
ATOM 7994 O O   . LEU B 1 525 ? 155.997 187.964 228.013 1.00 18.93 ? 509 LEU B O   1 
ATOM 7995 C CB  . LEU B 1 525 ? 156.100 186.431 230.309 1.00 18.93 ? 509 LEU B CB  1 
ATOM 7996 C CG  . LEU B 1 525 ? 155.678 185.642 231.550 1.00 18.93 ? 509 LEU B CG  1 
ATOM 7997 C CD1 . LEU B 1 525 ? 156.199 186.309 232.813 1.00 18.93 ? 509 LEU B CD1 1 
ATOM 7998 C CD2 . LEU B 1 525 ? 154.166 185.489 231.603 1.00 18.93 ? 509 LEU B CD2 1 
ATOM 7999 N N   . LEU B 1 526 ? 156.128 186.227 226.596 1.00 24.68 ? 510 LEU B N   1 
ATOM 8000 C CA  . LEU B 1 526 ? 156.247 187.046 225.395 1.00 24.68 ? 510 LEU B CA  1 
ATOM 8001 C C   . LEU B 1 526 ? 155.024 186.801 224.519 1.00 24.68 ? 510 LEU B C   1 
ATOM 8002 O O   . LEU B 1 526 ? 154.930 185.765 223.852 1.00 24.68 ? 510 LEU B O   1 
ATOM 8003 C CB  . LEU B 1 526 ? 157.534 186.727 224.637 1.00 24.68 ? 510 LEU B CB  1 
ATOM 8004 C CG  . LEU B 1 526 ? 158.853 186.878 225.398 1.00 24.68 ? 510 LEU B CG  1 
ATOM 8005 C CD1 . LEU B 1 526 ? 160.032 186.779 224.445 1.00 24.68 ? 510 LEU B CD1 1 
ATOM 8006 C CD2 . LEU B 1 526 ? 158.889 188.192 226.158 1.00 24.68 ? 510 LEU B CD2 1 
ATOM 8007 N N   . THR B 1 527 ? 154.094 187.749 224.521 1.00 25.75 ? 511 THR B N   1 
ATOM 8008 C CA  . THR B 1 527 ? 152.916 187.683 223.654 1.00 25.75 ? 511 THR B CA  1 
ATOM 8009 C C   . THR B 1 527 ? 153.174 188.393 222.332 1.00 25.75 ? 511 THR B C   1 
ATOM 8010 O O   . THR B 1 527 ? 152.386 189.223 221.878 1.00 25.75 ? 511 THR B O   1 
ATOM 8011 C CB  . THR B 1 527 ? 151.704 188.274 224.363 1.00 25.75 ? 511 THR B CB  1 
ATOM 8012 O OG1 . THR B 1 527 ? 151.891 189.684 224.537 1.00 25.75 ? 511 THR B OG1 1 
ATOM 8013 C CG2 . THR B 1 527 ? 151.512 187.621 225.724 1.00 25.75 ? 511 THR B CG2 1 
ATOM 8014 N N   . ASN B 1 528 ? 154.294 188.052 221.701 1.00 23.60 ? 512 ASN B N   1 
ATOM 8015 C CA  . ASN B 1 528 ? 154.709 188.602 220.419 1.00 23.60 ? 512 ASN B CA  1 
ATOM 8016 C C   . ASN B 1 528 ? 155.915 187.808 219.943 1.00 23.60 ? 512 ASN B C   1 
ATOM 8017 O O   . ASN B 1 528 ? 156.756 187.400 220.749 1.00 23.60 ? 512 ASN B O   1 
ATOM 8018 C CB  . ASN B 1 528 ? 155.055 190.095 220.525 1.00 23.60 ? 512 ASN B CB  1 
ATOM 8019 C CG  . ASN B 1 528 ? 155.778 190.619 219.297 1.00 23.60 ? 512 ASN B CG  1 
ATOM 8020 O OD1 . ASN B 1 528 ? 155.544 190.160 218.179 1.00 23.60 ? 512 ASN B OD1 1 
ATOM 8021 N ND2 . ASN B 1 528 ? 156.665 191.584 219.503 1.00 23.60 ? 512 ASN B ND2 1 
ATOM 8022 N N   . LEU B 1 529 ? 155.992 187.595 218.632 1.00 20.04 ? 513 LEU B N   1 
ATOM 8023 C CA  . LEU B 1 529 ? 157.074 186.813 218.042 1.00 20.04 ? 513 LEU B CA  1 
ATOM 8024 C C   . LEU B 1 529 ? 157.523 187.507 216.764 1.00 20.04 ? 513 LEU B C   1 
ATOM 8025 O O   . LEU B 1 529 ? 156.833 187.438 215.742 1.00 20.04 ? 513 LEU B O   1 
ATOM 8026 C CB  . LEU B 1 529 ? 156.628 185.378 217.762 1.00 20.04 ? 513 LEU B CB  1 
ATOM 8027 C CG  . LEU B 1 529 ? 157.643 184.281 218.085 1.00 20.04 ? 513 LEU B CG  1 
ATOM 8028 C CD1 . LEU B 1 529 ? 157.966 184.282 219.568 1.00 20.04 ? 513 LEU B CD1 1 
ATOM 8029 C CD2 . LEU B 1 529 ? 157.111 182.926 217.658 1.00 20.04 ? 513 LEU B CD2 1 
ATOM 8030 N N   . GLN B 1 530 ? 158.675 188.174 216.823 1.00 21.74 ? 514 GLN B N   1 
ATOM 8031 C CA  . GLN B 1 530 ? 159.228 188.862 215.662 1.00 21.74 ? 514 GLN B CA  1 
ATOM 8032 C C   . GLN B 1 530 ? 160.071 187.918 214.809 1.00 21.74 ? 514 GLN B C   1 
ATOM 8033 O O   . GLN B 1 530 ? 159.852 187.799 213.600 1.00 21.74 ? 514 GLN B O   1 
ATOM 8034 C CB  . GLN B 1 530 ? 160.058 190.069 216.114 1.00 21.74 ? 514 GLN B CB  1 
ATOM 8035 C CG  . GLN B 1 530 ? 160.509 190.975 214.980 1.00 21.74 ? 514 GLN B CG  1 
ATOM 8036 C CD  . GLN B 1 530 ? 159.461 192.002 214.603 1.00 21.74 ? 514 GLN B CD  1 
ATOM 8037 O OE1 . GLN B 1 530 ? 158.445 192.149 215.283 1.00 21.74 ? 514 GLN B OE1 1 
ATOM 8038 N NE2 . GLN B 1 530 ? 159.703 192.722 213.513 1.00 21.74 ? 514 GLN B NE2 1 
ATOM 8039 N N   . PHE B 1 531 ? 161.036 187.243 215.428 1.00 23.02 ? 515 PHE B N   1 
ATOM 8040 C CA  . PHE B 1 531 ? 161.908 186.315 214.726 1.00 23.02 ? 515 PHE B CA  1 
ATOM 8041 C C   . PHE B 1 531 ? 162.330 185.200 215.670 1.00 23.02 ? 515 PHE B C   1 
ATOM 8042 O O   . PHE B 1 531 ? 162.564 185.427 216.860 1.00 23.02 ? 515 PHE B O   1 
ATOM 8043 C CB  . PHE B 1 531 ? 163.151 187.020 214.166 1.00 23.02 ? 515 PHE B CB  1 
ATOM 8044 C CG  . PHE B 1 531 ? 162.940 187.647 212.818 1.00 23.02 ? 515 PHE B CG  1 
ATOM 8045 C CD1 . PHE B 1 531 ? 162.993 186.879 211.667 1.00 23.02 ? 515 PHE B CD1 1 
ATOM 8046 C CD2 . PHE B 1 531 ? 162.694 189.004 212.701 1.00 23.02 ? 515 PHE B CD2 1 
ATOM 8047 C CE1 . PHE B 1 531 ? 162.803 187.453 210.424 1.00 23.02 ? 515 PHE B CE1 1 
ATOM 8048 C CE2 . PHE B 1 531 ? 162.501 189.584 211.461 1.00 23.02 ? 515 PHE B CE2 1 
ATOM 8049 C CZ  . PHE B 1 531 ? 162.556 188.807 210.322 1.00 23.02 ? 515 PHE B CZ  1 
ATOM 8050 N N   . VAL B 1 532 ? 162.420 183.989 215.126 1.00 18.33 ? 516 VAL B N   1 
ATOM 8051 C CA  . VAL B 1 532 ? 162.928 182.828 215.847 1.00 18.33 ? 516 VAL B CA  1 
ATOM 8052 C C   . VAL B 1 532 ? 164.004 182.189 214.983 1.00 18.33 ? 516 VAL B C   1 
ATOM 8053 O O   . VAL B 1 532 ? 163.721 181.740 213.867 1.00 18.33 ? 516 VAL B O   1 
ATOM 8054 C CB  . VAL B 1 532 ? 161.819 181.814 216.173 1.00 18.33 ? 516 VAL B CB  1 
ATOM 8055 C CG1 . VAL B 1 532 ? 162.415 180.563 216.791 1.00 18.33 ? 516 VAL B CG1 1 
ATOM 8056 C CG2 . VAL B 1 532 ? 160.794 182.433 217.105 1.00 18.33 ? 516 VAL B CG2 1 
ATOM 8057 N N   . LEU B 1 533 ? 165.232 182.151 215.493 1.00 14.93 ? 517 LEU B N   1 
ATOM 8058 C CA  . LEU B 1 533 ? 166.379 181.650 214.748 1.00 14.93 ? 517 LEU B CA  1 
ATOM 8059 C C   . LEU B 1 533 ? 166.990 180.468 215.484 1.00 14.93 ? 517 LEU B C   1 
ATOM 8060 O O   . LEU B 1 533 ? 167.096 180.485 216.714 1.00 14.93 ? 517 LEU B O   1 
ATOM 8061 C CB  . LEU B 1 533 ? 167.429 182.746 214.547 1.00 14.93 ? 517 LEU B CB  1 
ATOM 8062 C CG  . LEU B 1 533 ? 167.301 183.617 213.294 1.00 14.93 ? 517 LEU B CG  1 
ATOM 8063 C CD1 . LEU B 1 533 ? 167.314 182.755 212.040 1.00 14.93 ? 517 LEU B CD1 1 
ATOM 8064 C CD2 . LEU B 1 533 ? 166.055 184.489 213.341 1.00 14.93 ? 517 LEU B CD2 1 
ATOM 8065 N N   . ALA B 1 534 ? 167.387 179.449 214.729 1.00 15.72 ? 518 ALA B N   1 
ATOM 8066 C CA  . ALA B 1 534 ? 168.014 178.265 215.304 1.00 15.72 ? 518 ALA B CA  1 
ATOM 8067 C C   . ALA B 1 534 ? 169.320 177.940 214.589 1.00 15.72 ? 518 ALA B C   1 
ATOM 8068 O O   . ALA B 1 534 ? 169.319 177.328 213.522 1.00 15.72 ? 518 ALA B O   1 
ATOM 8069 C CB  . ALA B 1 534 ? 167.067 177.080 215.239 1.00 15.72 ? 518 ALA B CB  1 
# 
