data_9DQ4
# 
_entry.id   9DQ4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DQ4         pdb_00009dq4 10.2210/pdb9dq4/pdb 
WWPDB D_1000288035 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DQ4 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              sjdiong0405@gmail.com 
_pdbx_contact_author.name_first         SJ 
_pdbx_contact_author.name_last          Diong 
_pdbx_contact_author.name_mi            J 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-4516-8355 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Diong, S.J.' 1 0000-0002-4516-8355 
'Lee, P.S.'   2 0000-0002-8745-4034 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Mabs 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1942-0870 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            17 
_citation.language                  ? 
_citation.page_first                2451296 
_citation.page_last                 2451296 
_citation.title                     'Engineered ipilimumab variants that bind human and mouse CTLA-4.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1080/19420862.2025.2451296 
_citation.pdbx_database_id_PubMed   39849917 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Robison, B.'  1  0000-0003-1159-9808 
primary 'Diong, S.J.'  2  0000-0002-4516-8355 
primary 'Kumar, A.'    3  ?                   
primary 'Moon, T.M.'   4  ?                   
primary 'Chang, O.'    5  ?                   
primary 'Chau, B.'     6  ?                   
primary 'Bee, C.'      7  ?                   
primary 'Barman, I.'   8  ?                   
primary 'Rajpal, A.'   9  ?                   
primary 'Korman, A.J.' 10 ?                   
primary 'West, S.'     11 ?                   
primary 'Strop, P.'    12 ?                   
primary 'Lee, P.S.'    13 0000-0002-8745-4034 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man 'Cytotoxic T-lymphocyte protein 4' 13916.556 1   ? ? ? ? 
2 polymer  man 'mipi.4 heavy chain' 24708.742 1   ? ? ? ? 
3 polymer  man 'mipi.4 light chain' 23608.199 1   ? ? ? ? 
4 branched man 
;beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
;
732.682   1   ? ? ? ? 
5 water    nat water 18.015    395 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EAIQVTQPSVVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPFCSGTFNESRVNLT
IQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTQIYVIDGHHHHHH
;
;EAIQVTQPSVVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPFCSGTFNESRVNLT
IQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTQIYVIDGHHHHHH
;
A ? 
2 'polypeptide(L)' no no 
;QVQLVESGGGVVQPGRSLRLSCAASGFTFSKYVMHWVRQAPGKGLEWVTGISYDGRHKYYADSVKGRFTISRDNSKNTLY
LQMNSLRAEDTAIYYCARTGWLGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWN
SGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCGGHHHHHH
;
;QVQLVESGGGVVQPGRSLRLSCAASGFTFSKYVMHWVRQAPGKGLEWVTGISYDGRHKYYADSVKGRFTISRDNSKNTLY
LQMNSLRAEDTAIYYCARTGWLGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWN
SGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCGGHHHHHH
;
H ? 
3 'polypeptide(L)' no no 
;EIVLTQSPGTLSLSPGERATLSCRQSQSVGWSPLAWYQQKPGQAPRLLIYGAFSRATGIPDRFSGSGSGTDFTLTISRLE
PEDFAVYYCQQYGQSPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;EIVLTQSPGTLSLSPGERATLSCRQSQSVGWSPLAWYQQKPGQAPRLLIYGAFSRATGIPDRFSGSGSGTDFTLTISRLE
PEDFAVYYCQQYGQSPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   ALA n 
1 3   ILE n 
1 4   GLN n 
1 5   VAL n 
1 6   THR n 
1 7   GLN n 
1 8   PRO n 
1 9   SER n 
1 10  VAL n 
1 11  VAL n 
1 12  LEU n 
1 13  ALA n 
1 14  SER n 
1 15  SER n 
1 16  HIS n 
1 17  GLY n 
1 18  VAL n 
1 19  ALA n 
1 20  SER n 
1 21  PHE n 
1 22  PRO n 
1 23  CYS n 
1 24  GLU n 
1 25  TYR n 
1 26  SER n 
1 27  PRO n 
1 28  SER n 
1 29  HIS n 
1 30  ASN n 
1 31  THR n 
1 32  ASP n 
1 33  GLU n 
1 34  VAL n 
1 35  ARG n 
1 36  VAL n 
1 37  THR n 
1 38  VAL n 
1 39  LEU n 
1 40  ARG n 
1 41  GLN n 
1 42  THR n 
1 43  ASN n 
1 44  ASP n 
1 45  GLN n 
1 46  MET n 
1 47  THR n 
1 48  GLU n 
1 49  VAL n 
1 50  CYS n 
1 51  ALA n 
1 52  THR n 
1 53  THR n 
1 54  PHE n 
1 55  THR n 
1 56  GLU n 
1 57  LYS n 
1 58  ASN n 
1 59  THR n 
1 60  VAL n 
1 61  GLY n 
1 62  PHE n 
1 63  LEU n 
1 64  ASP n 
1 65  TYR n 
1 66  PRO n 
1 67  PHE n 
1 68  CYS n 
1 69  SER n 
1 70  GLY n 
1 71  THR n 
1 72  PHE n 
1 73  ASN n 
1 74  GLU n 
1 75  SER n 
1 76  ARG n 
1 77  VAL n 
1 78  ASN n 
1 79  LEU n 
1 80  THR n 
1 81  ILE n 
1 82  GLN n 
1 83  GLY n 
1 84  LEU n 
1 85  ARG n 
1 86  ALA n 
1 87  VAL n 
1 88  ASP n 
1 89  THR n 
1 90  GLY n 
1 91  LEU n 
1 92  TYR n 
1 93  LEU n 
1 94  CYS n 
1 95  LYS n 
1 96  VAL n 
1 97  GLU n 
1 98  LEU n 
1 99  MET n 
1 100 TYR n 
1 101 PRO n 
1 102 PRO n 
1 103 PRO n 
1 104 TYR n 
1 105 PHE n 
1 106 VAL n 
1 107 GLY n 
1 108 MET n 
1 109 GLY n 
1 110 ASN n 
1 111 GLY n 
1 112 THR n 
1 113 GLN n 
1 114 ILE n 
1 115 TYR n 
1 116 VAL n 
1 117 ILE n 
1 118 ASP n 
1 119 GLY n 
1 120 HIS n 
1 121 HIS n 
1 122 HIS n 
1 123 HIS n 
1 124 HIS n 
1 125 HIS n 
2 1   GLN n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   VAL n 
2 6   GLU n 
2 7   SER n 
2 8   GLY n 
2 9   GLY n 
2 10  GLY n 
2 11  VAL n 
2 12  VAL n 
2 13  GLN n 
2 14  PRO n 
2 15  GLY n 
2 16  ARG n 
2 17  SER n 
2 18  LEU n 
2 19  ARG n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  ALA n 
2 24  ALA n 
2 25  SER n 
2 26  GLY n 
2 27  PHE n 
2 28  THR n 
2 29  PHE n 
2 30  SER n 
2 31  LYS n 
2 32  TYR n 
2 33  VAL n 
2 34  MET n 
2 35  HIS n 
2 36  TRP n 
2 37  VAL n 
2 38  ARG n 
2 39  GLN n 
2 40  ALA n 
2 41  PRO n 
2 42  GLY n 
2 43  LYS n 
2 44  GLY n 
2 45  LEU n 
2 46  GLU n 
2 47  TRP n 
2 48  VAL n 
2 49  THR n 
2 50  GLY n 
2 51  ILE n 
2 52  SER n 
2 53  TYR n 
2 54  ASP n 
2 55  GLY n 
2 56  ARG n 
2 57  HIS n 
2 58  LYS n 
2 59  TYR n 
2 60  TYR n 
2 61  ALA n 
2 62  ASP n 
2 63  SER n 
2 64  VAL n 
2 65  LYS n 
2 66  GLY n 
2 67  ARG n 
2 68  PHE n 
2 69  THR n 
2 70  ILE n 
2 71  SER n 
2 72  ARG n 
2 73  ASP n 
2 74  ASN n 
2 75  SER n 
2 76  LYS n 
2 77  ASN n 
2 78  THR n 
2 79  LEU n 
2 80  TYR n 
2 81  LEU n 
2 82  GLN n 
2 83  MET n 
2 84  ASN n 
2 85  SER n 
2 86  LEU n 
2 87  ARG n 
2 88  ALA n 
2 89  GLU n 
2 90  ASP n 
2 91  THR n 
2 92  ALA n 
2 93  ILE n 
2 94  TYR n 
2 95  TYR n 
2 96  CYS n 
2 97  ALA n 
2 98  ARG n 
2 99  THR n 
2 100 GLY n 
2 101 TRP n 
2 102 LEU n 
2 103 GLY n 
2 104 PRO n 
2 105 PHE n 
2 106 ASP n 
2 107 TYR n 
2 108 TRP n 
2 109 GLY n 
2 110 GLN n 
2 111 GLY n 
2 112 THR n 
2 113 LEU n 
2 114 VAL n 
2 115 THR n 
2 116 VAL n 
2 117 SER n 
2 118 SER n 
2 119 ALA n 
2 120 SER n 
2 121 THR n 
2 122 LYS n 
2 123 GLY n 
2 124 PRO n 
2 125 SER n 
2 126 VAL n 
2 127 PHE n 
2 128 PRO n 
2 129 LEU n 
2 130 ALA n 
2 131 PRO n 
2 132 SER n 
2 133 SER n 
2 134 LYS n 
2 135 SER n 
2 136 THR n 
2 137 SER n 
2 138 GLY n 
2 139 GLY n 
2 140 THR n 
2 141 ALA n 
2 142 ALA n 
2 143 LEU n 
2 144 GLY n 
2 145 CYS n 
2 146 LEU n 
2 147 VAL n 
2 148 LYS n 
2 149 ASP n 
2 150 TYR n 
2 151 PHE n 
2 152 PRO n 
2 153 GLU n 
2 154 PRO n 
2 155 VAL n 
2 156 THR n 
2 157 VAL n 
2 158 SER n 
2 159 TRP n 
2 160 ASN n 
2 161 SER n 
2 162 GLY n 
2 163 ALA n 
2 164 LEU n 
2 165 THR n 
2 166 SER n 
2 167 GLY n 
2 168 VAL n 
2 169 HIS n 
2 170 THR n 
2 171 PHE n 
2 172 PRO n 
2 173 ALA n 
2 174 VAL n 
2 175 LEU n 
2 176 GLN n 
2 177 SER n 
2 178 SER n 
2 179 GLY n 
2 180 LEU n 
2 181 TYR n 
2 182 SER n 
2 183 LEU n 
2 184 SER n 
2 185 SER n 
2 186 VAL n 
2 187 VAL n 
2 188 THR n 
2 189 VAL n 
2 190 PRO n 
2 191 SER n 
2 192 SER n 
2 193 SER n 
2 194 LEU n 
2 195 GLY n 
2 196 THR n 
2 197 GLN n 
2 198 THR n 
2 199 TYR n 
2 200 ILE n 
2 201 CYS n 
2 202 ASN n 
2 203 VAL n 
2 204 ASN n 
2 205 HIS n 
2 206 LYS n 
2 207 PRO n 
2 208 SER n 
2 209 ASN n 
2 210 THR n 
2 211 LYS n 
2 212 VAL n 
2 213 ASP n 
2 214 LYS n 
2 215 ARG n 
2 216 VAL n 
2 217 GLU n 
2 218 PRO n 
2 219 LYS n 
2 220 SER n 
2 221 CYS n 
2 222 GLY n 
2 223 GLY n 
2 224 HIS n 
2 225 HIS n 
2 226 HIS n 
2 227 HIS n 
2 228 HIS n 
2 229 HIS n 
3 1   GLU n 
3 2   ILE n 
3 3   VAL n 
3 4   LEU n 
3 5   THR n 
3 6   GLN n 
3 7   SER n 
3 8   PRO n 
3 9   GLY n 
3 10  THR n 
3 11  LEU n 
3 12  SER n 
3 13  LEU n 
3 14  SER n 
3 15  PRO n 
3 16  GLY n 
3 17  GLU n 
3 18  ARG n 
3 19  ALA n 
3 20  THR n 
3 21  LEU n 
3 22  SER n 
3 23  CYS n 
3 24  ARG n 
3 25  GLN n 
3 26  SER n 
3 27  GLN n 
3 28  SER n 
3 29  VAL n 
3 30  GLY n 
3 31  TRP n 
3 32  SER n 
3 33  PRO n 
3 34  LEU n 
3 35  ALA n 
3 36  TRP n 
3 37  TYR n 
3 38  GLN n 
3 39  GLN n 
3 40  LYS n 
3 41  PRO n 
3 42  GLY n 
3 43  GLN n 
3 44  ALA n 
3 45  PRO n 
3 46  ARG n 
3 47  LEU n 
3 48  LEU n 
3 49  ILE n 
3 50  TYR n 
3 51  GLY n 
3 52  ALA n 
3 53  PHE n 
3 54  SER n 
3 55  ARG n 
3 56  ALA n 
3 57  THR n 
3 58  GLY n 
3 59  ILE n 
3 60  PRO n 
3 61  ASP n 
3 62  ARG n 
3 63  PHE n 
3 64  SER n 
3 65  GLY n 
3 66  SER n 
3 67  GLY n 
3 68  SER n 
3 69  GLY n 
3 70  THR n 
3 71  ASP n 
3 72  PHE n 
3 73  THR n 
3 74  LEU n 
3 75  THR n 
3 76  ILE n 
3 77  SER n 
3 78  ARG n 
3 79  LEU n 
3 80  GLU n 
3 81  PRO n 
3 82  GLU n 
3 83  ASP n 
3 84  PHE n 
3 85  ALA n 
3 86  VAL n 
3 87  TYR n 
3 88  TYR n 
3 89  CYS n 
3 90  GLN n 
3 91  GLN n 
3 92  TYR n 
3 93  GLY n 
3 94  GLN n 
3 95  SER n 
3 96  PRO n 
3 97  TRP n 
3 98  THR n 
3 99  PHE n 
3 100 GLY n 
3 101 GLN n 
3 102 GLY n 
3 103 THR n 
3 104 LYS n 
3 105 VAL n 
3 106 GLU n 
3 107 ILE n 
3 108 LYS n 
3 109 ARG n 
3 110 THR n 
3 111 VAL n 
3 112 ALA n 
3 113 ALA n 
3 114 PRO n 
3 115 SER n 
3 116 VAL n 
3 117 PHE n 
3 118 ILE n 
3 119 PHE n 
3 120 PRO n 
3 121 PRO n 
3 122 SER n 
3 123 ASP n 
3 124 GLU n 
3 125 GLN n 
3 126 LEU n 
3 127 LYS n 
3 128 SER n 
3 129 GLY n 
3 130 THR n 
3 131 ALA n 
3 132 SER n 
3 133 VAL n 
3 134 VAL n 
3 135 CYS n 
3 136 LEU n 
3 137 LEU n 
3 138 ASN n 
3 139 ASN n 
3 140 PHE n 
3 141 TYR n 
3 142 PRO n 
3 143 ARG n 
3 144 GLU n 
3 145 ALA n 
3 146 LYS n 
3 147 VAL n 
3 148 GLN n 
3 149 TRP n 
3 150 LYS n 
3 151 VAL n 
3 152 ASP n 
3 153 ASN n 
3 154 ALA n 
3 155 LEU n 
3 156 GLN n 
3 157 SER n 
3 158 GLY n 
3 159 ASN n 
3 160 SER n 
3 161 GLN n 
3 162 GLU n 
3 163 SER n 
3 164 VAL n 
3 165 THR n 
3 166 GLU n 
3 167 GLN n 
3 168 ASP n 
3 169 SER n 
3 170 LYS n 
3 171 ASP n 
3 172 SER n 
3 173 THR n 
3 174 TYR n 
3 175 SER n 
3 176 LEU n 
3 177 SER n 
3 178 SER n 
3 179 THR n 
3 180 LEU n 
3 181 THR n 
3 182 LEU n 
3 183 SER n 
3 184 LYS n 
3 185 ALA n 
3 186 ASP n 
3 187 TYR n 
3 188 GLU n 
3 189 LYS n 
3 190 HIS n 
3 191 LYS n 
3 192 VAL n 
3 193 TYR n 
3 194 ALA n 
3 195 CYS n 
3 196 GLU n 
3 197 VAL n 
3 198 THR n 
3 199 HIS n 
3 200 GLN n 
3 201 GLY n 
3 202 LEU n 
3 203 SER n 
3 204 SER n 
3 205 PRO n 
3 206 VAL n 
3 207 THR n 
3 208 LYS n 
3 209 SER n 
3 210 PHE n 
3 211 ASN n 
3 212 ARG n 
3 213 GLY n 
3 214 GLU n 
3 215 CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 125 mouse ? 'Ctla4, Cd152' ? ? ? ? ? ? 'Mus musculus' 9606 ? Expi293F ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? Expi293F ?        ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 229 human ? ?              ? ? ? ? ? ? 'Homo sapiens' 9606 ? Expi293F ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? Expi293F ?        ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 215 human ? ?              ? ? ? ? ? ? 'Homo sapiens' 9606 ? Expi293F ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? Expi293F Expi293F ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   4 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 4 'DManpb1-4DGlcpNAcb1-4[LFucpa1-6]DGlcpNAcb1-ROH'                                                    
'Glycam Condensed Sequence' GMML       1.0   
2 4 'WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1221m-1a_1-5]/1-1-2-3/a4-b1_a6-d1_b4-c1' WURCS PDB2Glycan 1.1.0 
3 4 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}[(6+1)][a-L-Fucp]{}}'               LINUCS PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 4 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 4 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 4 4 FUC C1 O1 1 NAG O6 HO6 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
FUC 'L-saccharide, alpha linking' . alpha-L-fucopyranose                     
'alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose' 'C6 H12 O5'      164.156 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                                    ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
FUC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LFucpa                         
FUC 'COMMON NAME'                         GMML     1.0 a-L-fucopyranose               
FUC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Fucp                       
FUC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fuc                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   -1  ?   ?   ?   A . n 
A 1 2   ALA 2   0   ?   ?   ?   A . n 
A 1 3   ILE 3   1   1   ILE ILE A . n 
A 1 4   GLN 4   2   2   GLN GLN A . n 
A 1 5   VAL 5   3   3   VAL VAL A . n 
A 1 6   THR 6   4   4   THR THR A . n 
A 1 7   GLN 7   5   5   GLN GLN A . n 
A 1 8   PRO 8   6   6   PRO PRO A . n 
A 1 9   SER 9   7   7   SER SER A . n 
A 1 10  VAL 10  8   8   VAL VAL A . n 
A 1 11  VAL 11  9   9   VAL VAL A . n 
A 1 12  LEU 12  10  10  LEU LEU A . n 
A 1 13  ALA 13  11  11  ALA ALA A . n 
A 1 14  SER 14  12  12  SER SER A . n 
A 1 15  SER 15  13  13  SER SER A . n 
A 1 16  HIS 16  14  14  HIS HIS A . n 
A 1 17  GLY 17  15  15  GLY GLY A . n 
A 1 18  VAL 18  16  16  VAL VAL A . n 
A 1 19  ALA 19  17  17  ALA ALA A . n 
A 1 20  SER 20  18  18  SER SER A . n 
A 1 21  PHE 21  19  19  PHE PHE A . n 
A 1 22  PRO 22  20  20  PRO PRO A . n 
A 1 23  CYS 23  21  21  CYS CYS A . n 
A 1 24  GLU 24  22  22  GLU GLU A . n 
A 1 25  TYR 25  23  23  TYR TYR A . n 
A 1 26  SER 26  24  24  SER SER A . n 
A 1 27  PRO 27  25  25  PRO PRO A . n 
A 1 28  SER 28  26  26  SER SER A . n 
A 1 29  HIS 29  27  27  HIS HIS A . n 
A 1 30  ASN 30  28  28  ASN ASN A . n 
A 1 31  THR 31  29  29  THR THR A . n 
A 1 32  ASP 32  30  30  ASP ASP A . n 
A 1 33  GLU 33  31  31  GLU GLU A . n 
A 1 34  VAL 34  32  32  VAL VAL A . n 
A 1 35  ARG 35  33  33  ARG ARG A . n 
A 1 36  VAL 36  34  34  VAL VAL A . n 
A 1 37  THR 37  35  35  THR THR A . n 
A 1 38  VAL 38  36  36  VAL VAL A . n 
A 1 39  LEU 39  37  37  LEU LEU A . n 
A 1 40  ARG 40  38  38  ARG ARG A . n 
A 1 41  GLN 41  39  39  GLN GLN A . n 
A 1 42  THR 42  40  ?   ?   ?   A . n 
A 1 43  ASN 43  41  ?   ?   ?   A . n 
A 1 44  ASP 44  42  ?   ?   ?   A . n 
A 1 45  GLN 45  43  ?   ?   ?   A . n 
A 1 46  MET 46  44  44  MET MET A . n 
A 1 47  THR 47  45  45  THR THR A . n 
A 1 48  GLU 48  46  46  GLU GLU A . n 
A 1 49  VAL 49  47  47  VAL VAL A . n 
A 1 50  CYS 50  48  48  CYS CYS A . n 
A 1 51  ALA 51  49  49  ALA ALA A . n 
A 1 52  THR 52  50  50  THR THR A . n 
A 1 53  THR 53  51  51  THR THR A . n 
A 1 54  PHE 54  52  52  PHE PHE A . n 
A 1 55  THR 55  53  53  THR THR A . n 
A 1 56  GLU 56  54  ?   ?   ?   A . n 
A 1 57  LYS 57  55  ?   ?   ?   A . n 
A 1 58  ASN 58  56  ?   ?   ?   A . n 
A 1 59  THR 59  57  ?   ?   ?   A . n 
A 1 60  VAL 60  58  58  VAL VAL A . n 
A 1 61  GLY 61  59  59  GLY GLY A . n 
A 1 62  PHE 62  60  60  PHE PHE A . n 
A 1 63  LEU 63  61  61  LEU LEU A . n 
A 1 64  ASP 64  62  62  ASP ASP A . n 
A 1 65  TYR 65  63  63  TYR TYR A . n 
A 1 66  PRO 66  64  64  PRO PRO A . n 
A 1 67  PHE 67  65  65  PHE PHE A . n 
A 1 68  CYS 68  66  66  CYS CYS A . n 
A 1 69  SER 69  67  67  SER SER A . n 
A 1 70  GLY 70  68  68  GLY GLY A . n 
A 1 71  THR 71  69  69  THR THR A . n 
A 1 72  PHE 72  70  70  PHE PHE A . n 
A 1 73  ASN 73  71  71  ASN ASN A . n 
A 1 74  GLU 74  72  72  GLU GLU A . n 
A 1 75  SER 75  73  73  SER SER A . n 
A 1 76  ARG 76  74  74  ARG ARG A . n 
A 1 77  VAL 77  75  75  VAL VAL A . n 
A 1 78  ASN 78  76  76  ASN ASN A . n 
A 1 79  LEU 79  77  77  LEU LEU A . n 
A 1 80  THR 80  78  78  THR THR A . n 
A 1 81  ILE 81  79  79  ILE ILE A . n 
A 1 82  GLN 82  80  80  GLN GLN A . n 
A 1 83  GLY 83  81  81  GLY GLY A . n 
A 1 84  LEU 84  82  82  LEU LEU A . n 
A 1 85  ARG 85  83  83  ARG ARG A . n 
A 1 86  ALA 86  84  84  ALA ALA A . n 
A 1 87  VAL 87  85  85  VAL VAL A . n 
A 1 88  ASP 88  86  86  ASP ASP A . n 
A 1 89  THR 89  87  87  THR THR A . n 
A 1 90  GLY 90  88  88  GLY GLY A . n 
A 1 91  LEU 91  89  89  LEU LEU A . n 
A 1 92  TYR 92  90  90  TYR TYR A . n 
A 1 93  LEU 93  91  91  LEU LEU A . n 
A 1 94  CYS 94  92  92  CYS CYS A . n 
A 1 95  LYS 95  93  93  LYS LYS A . n 
A 1 96  VAL 96  94  94  VAL VAL A . n 
A 1 97  GLU 97  95  95  GLU GLU A . n 
A 1 98  LEU 98  96  96  LEU LEU A . n 
A 1 99  MET 99  97  97  MET MET A . n 
A 1 100 TYR 100 98  98  TYR TYR A . n 
A 1 101 PRO 101 99  99  PRO PRO A . n 
A 1 102 PRO 102 100 100 PRO PRO A . n 
A 1 103 PRO 103 101 101 PRO PRO A . n 
A 1 104 TYR 104 102 102 TYR TYR A . n 
A 1 105 PHE 105 103 103 PHE PHE A . n 
A 1 106 VAL 106 104 104 VAL VAL A . n 
A 1 107 GLY 107 105 105 GLY GLY A . n 
A 1 108 MET 108 106 106 MET MET A . n 
A 1 109 GLY 109 107 107 GLY GLY A . n 
A 1 110 ASN 110 108 108 ASN ASN A . n 
A 1 111 GLY 111 109 109 GLY GLY A . n 
A 1 112 THR 112 110 110 THR THR A . n 
A 1 113 GLN 113 111 111 GLN GLN A . n 
A 1 114 ILE 114 112 112 ILE ILE A . n 
A 1 115 TYR 115 113 113 TYR TYR A . n 
A 1 116 VAL 116 114 114 VAL VAL A . n 
A 1 117 ILE 117 115 115 ILE ILE A . n 
A 1 118 ASP 118 116 116 ASP ASP A . n 
A 1 119 GLY 119 117 ?   ?   ?   A . n 
A 1 120 HIS 120 118 ?   ?   ?   A . n 
A 1 121 HIS 121 119 ?   ?   ?   A . n 
A 1 122 HIS 122 120 ?   ?   ?   A . n 
A 1 123 HIS 123 121 ?   ?   ?   A . n 
A 1 124 HIS 124 122 ?   ?   ?   A . n 
A 1 125 HIS 125 123 ?   ?   ?   A . n 
B 2 1   GLN 1   1   1   GLN GLN H . n 
B 2 2   VAL 2   2   2   VAL VAL H . n 
B 2 3   GLN 3   3   3   GLN GLN H . n 
B 2 4   LEU 4   4   4   LEU LEU H . n 
B 2 5   VAL 5   5   5   VAL VAL H . n 
B 2 6   GLU 6   6   6   GLU GLU H . n 
B 2 7   SER 7   7   7   SER SER H . n 
B 2 8   GLY 8   8   8   GLY GLY H . n 
B 2 9   GLY 9   9   9   GLY GLY H . n 
B 2 10  GLY 10  10  10  GLY GLY H . n 
B 2 11  VAL 11  11  11  VAL VAL H . n 
B 2 12  VAL 12  12  12  VAL VAL H . n 
B 2 13  GLN 13  13  13  GLN GLN H . n 
B 2 14  PRO 14  14  14  PRO PRO H . n 
B 2 15  GLY 15  15  15  GLY GLY H . n 
B 2 16  ARG 16  16  16  ARG ARG H . n 
B 2 17  SER 17  17  17  SER SER H . n 
B 2 18  LEU 18  18  18  LEU LEU H . n 
B 2 19  ARG 19  19  19  ARG ARG H . n 
B 2 20  LEU 20  20  20  LEU LEU H . n 
B 2 21  SER 21  21  21  SER SER H . n 
B 2 22  CYS 22  22  22  CYS CYS H . n 
B 2 23  ALA 23  23  23  ALA ALA H . n 
B 2 24  ALA 24  24  24  ALA ALA H . n 
B 2 25  SER 25  25  25  SER SER H . n 
B 2 26  GLY 26  26  26  GLY GLY H . n 
B 2 27  PHE 27  27  27  PHE PHE H . n 
B 2 28  THR 28  28  28  THR THR H . n 
B 2 29  PHE 29  29  29  PHE PHE H . n 
B 2 30  SER 30  30  30  SER SER H . n 
B 2 31  LYS 31  31  31  LYS LYS H . n 
B 2 32  TYR 32  32  32  TYR TYR H . n 
B 2 33  VAL 33  33  33  VAL VAL H . n 
B 2 34  MET 34  34  34  MET MET H . n 
B 2 35  HIS 35  35  35  HIS HIS H . n 
B 2 36  TRP 36  36  36  TRP TRP H . n 
B 2 37  VAL 37  37  37  VAL VAL H . n 
B 2 38  ARG 38  38  38  ARG ARG H . n 
B 2 39  GLN 39  39  39  GLN GLN H . n 
B 2 40  ALA 40  40  40  ALA ALA H . n 
B 2 41  PRO 41  41  41  PRO PRO H . n 
B 2 42  GLY 42  42  42  GLY GLY H . n 
B 2 43  LYS 43  43  43  LYS LYS H . n 
B 2 44  GLY 44  44  44  GLY GLY H . n 
B 2 45  LEU 45  45  45  LEU LEU H . n 
B 2 46  GLU 46  46  46  GLU GLU H . n 
B 2 47  TRP 47  47  47  TRP TRP H . n 
B 2 48  VAL 48  48  48  VAL VAL H . n 
B 2 49  THR 49  49  49  THR THR H . n 
B 2 50  GLY 50  50  50  GLY GLY H . n 
B 2 51  ILE 51  51  51  ILE ILE H . n 
B 2 52  SER 52  52  52  SER SER H . n 
B 2 53  TYR 53  53  53  TYR TYR H . n 
B 2 54  ASP 54  54  54  ASP ASP H . n 
B 2 55  GLY 55  55  55  GLY GLY H . n 
B 2 56  ARG 56  56  56  ARG ARG H . n 
B 2 57  HIS 57  57  57  HIS HIS H . n 
B 2 58  LYS 58  58  58  LYS LYS H . n 
B 2 59  TYR 59  59  59  TYR TYR H . n 
B 2 60  TYR 60  60  60  TYR TYR H . n 
B 2 61  ALA 61  61  61  ALA ALA H . n 
B 2 62  ASP 62  62  62  ASP ASP H . n 
B 2 63  SER 63  63  63  SER SER H . n 
B 2 64  VAL 64  64  64  VAL VAL H . n 
B 2 65  LYS 65  65  65  LYS LYS H . n 
B 2 66  GLY 66  66  66  GLY GLY H . n 
B 2 67  ARG 67  67  67  ARG ARG H . n 
B 2 68  PHE 68  68  68  PHE PHE H . n 
B 2 69  THR 69  69  69  THR THR H . n 
B 2 70  ILE 70  70  70  ILE ILE H . n 
B 2 71  SER 71  71  71  SER SER H . n 
B 2 72  ARG 72  72  72  ARG ARG H . n 
B 2 73  ASP 73  73  73  ASP ASP H . n 
B 2 74  ASN 74  74  74  ASN ASN H . n 
B 2 75  SER 75  75  75  SER SER H . n 
B 2 76  LYS 76  76  76  LYS LYS H . n 
B 2 77  ASN 77  77  77  ASN ASN H . n 
B 2 78  THR 78  78  78  THR THR H . n 
B 2 79  LEU 79  79  79  LEU LEU H . n 
B 2 80  TYR 80  80  80  TYR TYR H . n 
B 2 81  LEU 81  81  81  LEU LEU H . n 
B 2 82  GLN 82  82  82  GLN GLN H . n 
B 2 83  MET 83  83  83  MET MET H . n 
B 2 84  ASN 84  84  84  ASN ASN H . n 
B 2 85  SER 85  85  85  SER SER H . n 
B 2 86  LEU 86  86  86  LEU LEU H . n 
B 2 87  ARG 87  87  87  ARG ARG H . n 
B 2 88  ALA 88  88  88  ALA ALA H . n 
B 2 89  GLU 89  89  89  GLU GLU H . n 
B 2 90  ASP 90  90  90  ASP ASP H . n 
B 2 91  THR 91  91  91  THR THR H . n 
B 2 92  ALA 92  92  92  ALA ALA H . n 
B 2 93  ILE 93  93  93  ILE ILE H . n 
B 2 94  TYR 94  94  94  TYR TYR H . n 
B 2 95  TYR 95  95  95  TYR TYR H . n 
B 2 96  CYS 96  96  96  CYS CYS H . n 
B 2 97  ALA 97  97  97  ALA ALA H . n 
B 2 98  ARG 98  98  98  ARG ARG H . n 
B 2 99  THR 99  99  99  THR THR H . n 
B 2 100 GLY 100 100 100 GLY GLY H . n 
B 2 101 TRP 101 101 101 TRP TRP H . n 
B 2 102 LEU 102 102 102 LEU LEU H . n 
B 2 103 GLY 103 103 103 GLY GLY H . n 
B 2 104 PRO 104 104 104 PRO PRO H . n 
B 2 105 PHE 105 105 105 PHE PHE H . n 
B 2 106 ASP 106 106 106 ASP ASP H . n 
B 2 107 TYR 107 107 107 TYR TYR H . n 
B 2 108 TRP 108 108 108 TRP TRP H . n 
B 2 109 GLY 109 109 109 GLY GLY H . n 
B 2 110 GLN 110 110 110 GLN GLN H . n 
B 2 111 GLY 111 111 111 GLY GLY H . n 
B 2 112 THR 112 112 112 THR THR H . n 
B 2 113 LEU 113 113 113 LEU LEU H . n 
B 2 114 VAL 114 114 114 VAL VAL H . n 
B 2 115 THR 115 115 115 THR THR H . n 
B 2 116 VAL 116 116 116 VAL VAL H . n 
B 2 117 SER 117 117 117 SER SER H . n 
B 2 118 SER 118 118 118 SER SER H . n 
B 2 119 ALA 119 119 119 ALA ALA H . n 
B 2 120 SER 120 120 120 SER SER H . n 
B 2 121 THR 121 121 121 THR THR H . n 
B 2 122 LYS 122 122 122 LYS LYS H . n 
B 2 123 GLY 123 123 123 GLY GLY H . n 
B 2 124 PRO 124 124 124 PRO PRO H . n 
B 2 125 SER 125 125 125 SER SER H . n 
B 2 126 VAL 126 126 126 VAL VAL H . n 
B 2 127 PHE 127 127 127 PHE PHE H . n 
B 2 128 PRO 128 128 128 PRO PRO H . n 
B 2 129 LEU 129 129 129 LEU LEU H . n 
B 2 130 ALA 130 130 130 ALA ALA H . n 
B 2 131 PRO 131 131 131 PRO PRO H . n 
B 2 132 SER 132 132 ?   ?   ?   H . n 
B 2 133 SER 133 133 ?   ?   ?   H . n 
B 2 134 LYS 134 134 ?   ?   ?   H . n 
B 2 135 SER 135 135 ?   ?   ?   H . n 
B 2 136 THR 136 136 ?   ?   ?   H . n 
B 2 137 SER 137 137 ?   ?   ?   H . n 
B 2 138 GLY 138 138 ?   ?   ?   H . n 
B 2 139 GLY 139 139 139 GLY GLY H . n 
B 2 140 THR 140 140 140 THR THR H . n 
B 2 141 ALA 141 141 141 ALA ALA H . n 
B 2 142 ALA 142 142 142 ALA ALA H . n 
B 2 143 LEU 143 143 143 LEU LEU H . n 
B 2 144 GLY 144 144 144 GLY GLY H . n 
B 2 145 CYS 145 145 145 CYS CYS H . n 
B 2 146 LEU 146 146 146 LEU LEU H . n 
B 2 147 VAL 147 147 147 VAL VAL H . n 
B 2 148 LYS 148 148 148 LYS LYS H . n 
B 2 149 ASP 149 149 149 ASP ASP H . n 
B 2 150 TYR 150 150 150 TYR TYR H . n 
B 2 151 PHE 151 151 151 PHE PHE H . n 
B 2 152 PRO 152 152 152 PRO PRO H . n 
B 2 153 GLU 153 153 153 GLU GLU H . n 
B 2 154 PRO 154 154 154 PRO PRO H . n 
B 2 155 VAL 155 155 155 VAL VAL H . n 
B 2 156 THR 156 156 156 THR THR H . n 
B 2 157 VAL 157 157 157 VAL VAL H . n 
B 2 158 SER 158 158 158 SER SER H . n 
B 2 159 TRP 159 159 159 TRP TRP H . n 
B 2 160 ASN 160 160 160 ASN ASN H . n 
B 2 161 SER 161 161 161 SER SER H . n 
B 2 162 GLY 162 162 162 GLY GLY H . n 
B 2 163 ALA 163 163 163 ALA ALA H . n 
B 2 164 LEU 164 164 164 LEU LEU H . n 
B 2 165 THR 165 165 165 THR THR H . n 
B 2 166 SER 166 166 166 SER SER H . n 
B 2 167 GLY 167 167 167 GLY GLY H . n 
B 2 168 VAL 168 168 168 VAL VAL H . n 
B 2 169 HIS 169 169 169 HIS HIS H . n 
B 2 170 THR 170 170 170 THR THR H . n 
B 2 171 PHE 171 171 171 PHE PHE H . n 
B 2 172 PRO 172 172 172 PRO PRO H . n 
B 2 173 ALA 173 173 173 ALA ALA H . n 
B 2 174 VAL 174 174 174 VAL VAL H . n 
B 2 175 LEU 175 175 175 LEU LEU H . n 
B 2 176 GLN 176 176 176 GLN GLN H . n 
B 2 177 SER 177 177 177 SER SER H . n 
B 2 178 SER 178 178 178 SER SER H . n 
B 2 179 GLY 179 179 179 GLY GLY H . n 
B 2 180 LEU 180 180 180 LEU LEU H . n 
B 2 181 TYR 181 181 181 TYR TYR H . n 
B 2 182 SER 182 182 182 SER SER H . n 
B 2 183 LEU 183 183 183 LEU LEU H . n 
B 2 184 SER 184 184 184 SER SER H . n 
B 2 185 SER 185 185 185 SER SER H . n 
B 2 186 VAL 186 186 186 VAL VAL H . n 
B 2 187 VAL 187 187 187 VAL VAL H . n 
B 2 188 THR 188 188 188 THR THR H . n 
B 2 189 VAL 189 189 189 VAL VAL H . n 
B 2 190 PRO 190 190 190 PRO PRO H . n 
B 2 191 SER 191 191 191 SER SER H . n 
B 2 192 SER 192 192 192 SER SER H . n 
B 2 193 SER 193 193 193 SER SER H . n 
B 2 194 LEU 194 194 194 LEU LEU H . n 
B 2 195 GLY 195 195 195 GLY GLY H . n 
B 2 196 THR 196 196 196 THR THR H . n 
B 2 197 GLN 197 197 197 GLN GLN H . n 
B 2 198 THR 198 198 198 THR THR H . n 
B 2 199 TYR 199 199 199 TYR TYR H . n 
B 2 200 ILE 200 200 200 ILE ILE H . n 
B 2 201 CYS 201 201 201 CYS CYS H . n 
B 2 202 ASN 202 202 202 ASN ASN H . n 
B 2 203 VAL 203 203 203 VAL VAL H . n 
B 2 204 ASN 204 204 204 ASN ASN H . n 
B 2 205 HIS 205 205 205 HIS HIS H . n 
B 2 206 LYS 206 206 206 LYS LYS H . n 
B 2 207 PRO 207 207 207 PRO PRO H . n 
B 2 208 SER 208 208 208 SER SER H . n 
B 2 209 ASN 209 209 209 ASN ASN H . n 
B 2 210 THR 210 210 210 THR THR H . n 
B 2 211 LYS 211 211 211 LYS LYS H . n 
B 2 212 VAL 212 212 212 VAL VAL H . n 
B 2 213 ASP 213 213 213 ASP ASP H . n 
B 2 214 LYS 214 214 214 LYS LYS H . n 
B 2 215 ARG 215 215 215 ARG ARG H . n 
B 2 216 VAL 216 216 216 VAL VAL H . n 
B 2 217 GLU 217 217 217 GLU GLU H . n 
B 2 218 PRO 218 218 218 PRO PRO H . n 
B 2 219 LYS 219 219 219 LYS LYS H . n 
B 2 220 SER 220 220 ?   ?   ?   H . n 
B 2 221 CYS 221 221 ?   ?   ?   H . n 
B 2 222 GLY 222 222 ?   ?   ?   H . n 
B 2 223 GLY 223 223 ?   ?   ?   H . n 
B 2 224 HIS 224 224 ?   ?   ?   H . n 
B 2 225 HIS 225 225 ?   ?   ?   H . n 
B 2 226 HIS 226 226 ?   ?   ?   H . n 
B 2 227 HIS 227 227 ?   ?   ?   H . n 
B 2 228 HIS 228 228 ?   ?   ?   H . n 
B 2 229 HIS 229 229 ?   ?   ?   H . n 
C 3 1   GLU 1   1   1   GLU GLU L . n 
C 3 2   ILE 2   2   2   ILE ILE L . n 
C 3 3   VAL 3   3   3   VAL VAL L . n 
C 3 4   LEU 4   4   4   LEU LEU L . n 
C 3 5   THR 5   5   5   THR THR L . n 
C 3 6   GLN 6   6   6   GLN GLN L . n 
C 3 7   SER 7   7   7   SER SER L . n 
C 3 8   PRO 8   8   8   PRO PRO L . n 
C 3 9   GLY 9   9   9   GLY GLY L . n 
C 3 10  THR 10  10  10  THR THR L . n 
C 3 11  LEU 11  11  11  LEU LEU L . n 
C 3 12  SER 12  12  12  SER SER L . n 
C 3 13  LEU 13  13  13  LEU LEU L . n 
C 3 14  SER 14  14  14  SER SER L . n 
C 3 15  PRO 15  15  15  PRO PRO L . n 
C 3 16  GLY 16  16  16  GLY GLY L . n 
C 3 17  GLU 17  17  17  GLU GLU L . n 
C 3 18  ARG 18  18  18  ARG ARG L . n 
C 3 19  ALA 19  19  19  ALA ALA L . n 
C 3 20  THR 20  20  20  THR THR L . n 
C 3 21  LEU 21  21  21  LEU LEU L . n 
C 3 22  SER 22  22  22  SER SER L . n 
C 3 23  CYS 23  23  23  CYS CYS L . n 
C 3 24  ARG 24  24  24  ARG ARG L . n 
C 3 25  GLN 25  25  25  GLN GLN L . n 
C 3 26  SER 26  26  26  SER SER L . n 
C 3 27  GLN 27  27  27  GLN GLN L . n 
C 3 28  SER 28  28  28  SER SER L . n 
C 3 29  VAL 29  29  29  VAL VAL L . n 
C 3 30  GLY 30  30  30  GLY GLY L . n 
C 3 31  TRP 31  31  31  TRP TRP L . n 
C 3 32  SER 32  32  32  SER SER L . n 
C 3 33  PRO 33  33  33  PRO PRO L . n 
C 3 34  LEU 34  34  34  LEU LEU L . n 
C 3 35  ALA 35  35  35  ALA ALA L . n 
C 3 36  TRP 36  36  36  TRP TRP L . n 
C 3 37  TYR 37  37  37  TYR TYR L . n 
C 3 38  GLN 38  38  38  GLN GLN L . n 
C 3 39  GLN 39  39  39  GLN GLN L . n 
C 3 40  LYS 40  40  40  LYS LYS L . n 
C 3 41  PRO 41  41  41  PRO PRO L . n 
C 3 42  GLY 42  42  42  GLY GLY L . n 
C 3 43  GLN 43  43  43  GLN GLN L . n 
C 3 44  ALA 44  44  44  ALA ALA L . n 
C 3 45  PRO 45  45  45  PRO PRO L . n 
C 3 46  ARG 46  46  46  ARG ARG L . n 
C 3 47  LEU 47  47  47  LEU LEU L . n 
C 3 48  LEU 48  48  48  LEU LEU L . n 
C 3 49  ILE 49  49  49  ILE ILE L . n 
C 3 50  TYR 50  50  50  TYR TYR L . n 
C 3 51  GLY 51  51  51  GLY GLY L . n 
C 3 52  ALA 52  52  52  ALA ALA L . n 
C 3 53  PHE 53  53  53  PHE PHE L . n 
C 3 54  SER 54  54  54  SER SER L . n 
C 3 55  ARG 55  55  55  ARG ARG L . n 
C 3 56  ALA 56  56  56  ALA ALA L . n 
C 3 57  THR 57  57  57  THR THR L . n 
C 3 58  GLY 58  58  58  GLY GLY L . n 
C 3 59  ILE 59  59  59  ILE ILE L . n 
C 3 60  PRO 60  60  60  PRO PRO L . n 
C 3 61  ASP 61  61  61  ASP ASP L . n 
C 3 62  ARG 62  62  62  ARG ARG L . n 
C 3 63  PHE 63  63  63  PHE PHE L . n 
C 3 64  SER 64  64  64  SER SER L . n 
C 3 65  GLY 65  65  65  GLY GLY L . n 
C 3 66  SER 66  66  66  SER SER L . n 
C 3 67  GLY 67  67  67  GLY GLY L . n 
C 3 68  SER 68  68  68  SER SER L . n 
C 3 69  GLY 69  69  69  GLY GLY L . n 
C 3 70  THR 70  70  70  THR THR L . n 
C 3 71  ASP 71  71  71  ASP ASP L . n 
C 3 72  PHE 72  72  72  PHE PHE L . n 
C 3 73  THR 73  73  73  THR THR L . n 
C 3 74  LEU 74  74  74  LEU LEU L . n 
C 3 75  THR 75  75  75  THR THR L . n 
C 3 76  ILE 76  76  76  ILE ILE L . n 
C 3 77  SER 77  77  77  SER SER L . n 
C 3 78  ARG 78  78  78  ARG ARG L . n 
C 3 79  LEU 79  79  79  LEU LEU L . n 
C 3 80  GLU 80  80  80  GLU GLU L . n 
C 3 81  PRO 81  81  81  PRO PRO L . n 
C 3 82  GLU 82  82  82  GLU GLU L . n 
C 3 83  ASP 83  83  83  ASP ASP L . n 
C 3 84  PHE 84  84  84  PHE PHE L . n 
C 3 85  ALA 85  85  85  ALA ALA L . n 
C 3 86  VAL 86  86  86  VAL VAL L . n 
C 3 87  TYR 87  87  87  TYR TYR L . n 
C 3 88  TYR 88  88  88  TYR TYR L . n 
C 3 89  CYS 89  89  89  CYS CYS L . n 
C 3 90  GLN 90  90  90  GLN GLN L . n 
C 3 91  GLN 91  91  91  GLN GLN L . n 
C 3 92  TYR 92  92  92  TYR TYR L . n 
C 3 93  GLY 93  93  93  GLY GLY L . n 
C 3 94  GLN 94  94  94  GLN GLN L . n 
C 3 95  SER 95  95  95  SER SER L . n 
C 3 96  PRO 96  96  96  PRO PRO L . n 
C 3 97  TRP 97  97  97  TRP TRP L . n 
C 3 98  THR 98  98  98  THR THR L . n 
C 3 99  PHE 99  99  99  PHE PHE L . n 
C 3 100 GLY 100 100 100 GLY GLY L . n 
C 3 101 GLN 101 101 101 GLN GLN L . n 
C 3 102 GLY 102 102 102 GLY GLY L . n 
C 3 103 THR 103 103 103 THR THR L . n 
C 3 104 LYS 104 104 104 LYS LYS L . n 
C 3 105 VAL 105 105 105 VAL VAL L . n 
C 3 106 GLU 106 106 106 GLU GLU L . n 
C 3 107 ILE 107 107 107 ILE ILE L . n 
C 3 108 LYS 108 108 108 LYS LYS L . n 
C 3 109 ARG 109 109 109 ARG ARG L . n 
C 3 110 THR 110 110 110 THR THR L . n 
C 3 111 VAL 111 111 111 VAL VAL L . n 
C 3 112 ALA 112 112 112 ALA ALA L . n 
C 3 113 ALA 113 113 113 ALA ALA L . n 
C 3 114 PRO 114 114 114 PRO PRO L . n 
C 3 115 SER 115 115 115 SER SER L . n 
C 3 116 VAL 116 116 116 VAL VAL L . n 
C 3 117 PHE 117 117 117 PHE PHE L . n 
C 3 118 ILE 118 118 118 ILE ILE L . n 
C 3 119 PHE 119 119 119 PHE PHE L . n 
C 3 120 PRO 120 120 120 PRO PRO L . n 
C 3 121 PRO 121 121 121 PRO PRO L . n 
C 3 122 SER 122 122 122 SER SER L . n 
C 3 123 ASP 123 123 123 ASP ASP L . n 
C 3 124 GLU 124 124 124 GLU GLU L . n 
C 3 125 GLN 125 125 125 GLN GLN L . n 
C 3 126 LEU 126 126 126 LEU LEU L . n 
C 3 127 LYS 127 127 127 LYS LYS L . n 
C 3 128 SER 128 128 128 SER SER L . n 
C 3 129 GLY 129 129 129 GLY GLY L . n 
C 3 130 THR 130 130 130 THR THR L . n 
C 3 131 ALA 131 131 131 ALA ALA L . n 
C 3 132 SER 132 132 132 SER SER L . n 
C 3 133 VAL 133 133 133 VAL VAL L . n 
C 3 134 VAL 134 134 134 VAL VAL L . n 
C 3 135 CYS 135 135 135 CYS CYS L . n 
C 3 136 LEU 136 136 136 LEU LEU L . n 
C 3 137 LEU 137 137 137 LEU LEU L . n 
C 3 138 ASN 138 138 138 ASN ASN L . n 
C 3 139 ASN 139 139 139 ASN ASN L . n 
C 3 140 PHE 140 140 140 PHE PHE L . n 
C 3 141 TYR 141 141 141 TYR TYR L . n 
C 3 142 PRO 142 142 142 PRO PRO L . n 
C 3 143 ARG 143 143 143 ARG ARG L . n 
C 3 144 GLU 144 144 144 GLU GLU L . n 
C 3 145 ALA 145 145 145 ALA ALA L . n 
C 3 146 LYS 146 146 146 LYS LYS L . n 
C 3 147 VAL 147 147 147 VAL VAL L . n 
C 3 148 GLN 148 148 148 GLN GLN L . n 
C 3 149 TRP 149 149 149 TRP TRP L . n 
C 3 150 LYS 150 150 150 LYS LYS L . n 
C 3 151 VAL 151 151 151 VAL VAL L . n 
C 3 152 ASP 152 152 152 ASP ASP L . n 
C 3 153 ASN 153 153 153 ASN ASN L . n 
C 3 154 ALA 154 154 154 ALA ALA L . n 
C 3 155 LEU 155 155 155 LEU LEU L . n 
C 3 156 GLN 156 156 156 GLN GLN L . n 
C 3 157 SER 157 157 157 SER SER L . n 
C 3 158 GLY 158 158 158 GLY GLY L . n 
C 3 159 ASN 159 159 159 ASN ASN L . n 
C 3 160 SER 160 160 160 SER SER L . n 
C 3 161 GLN 161 161 161 GLN GLN L . n 
C 3 162 GLU 162 162 162 GLU GLU L . n 
C 3 163 SER 163 163 163 SER SER L . n 
C 3 164 VAL 164 164 164 VAL VAL L . n 
C 3 165 THR 165 165 165 THR THR L . n 
C 3 166 GLU 166 166 166 GLU GLU L . n 
C 3 167 GLN 167 167 167 GLN GLN L . n 
C 3 168 ASP 168 168 168 ASP ASP L . n 
C 3 169 SER 169 169 169 SER SER L . n 
C 3 170 LYS 170 170 170 LYS LYS L . n 
C 3 171 ASP 171 171 171 ASP ASP L . n 
C 3 172 SER 172 172 172 SER SER L . n 
C 3 173 THR 173 173 173 THR THR L . n 
C 3 174 TYR 174 174 174 TYR TYR L . n 
C 3 175 SER 175 175 175 SER SER L . n 
C 3 176 LEU 176 176 176 LEU LEU L . n 
C 3 177 SER 177 177 177 SER SER L . n 
C 3 178 SER 178 178 178 SER SER L . n 
C 3 179 THR 179 179 179 THR THR L . n 
C 3 180 LEU 180 180 180 LEU LEU L . n 
C 3 181 THR 181 181 181 THR THR L . n 
C 3 182 LEU 182 182 182 LEU LEU L . n 
C 3 183 SER 183 183 183 SER SER L . n 
C 3 184 LYS 184 184 184 LYS LYS L . n 
C 3 185 ALA 185 185 185 ALA ALA L . n 
C 3 186 ASP 186 186 186 ASP ASP L . n 
C 3 187 TYR 187 187 187 TYR TYR L . n 
C 3 188 GLU 188 188 188 GLU GLU L . n 
C 3 189 LYS 189 189 189 LYS LYS L . n 
C 3 190 HIS 190 190 190 HIS HIS L . n 
C 3 191 LYS 191 191 191 LYS LYS L . n 
C 3 192 VAL 192 192 192 VAL VAL L . n 
C 3 193 TYR 193 193 193 TYR TYR L . n 
C 3 194 ALA 194 194 194 ALA ALA L . n 
C 3 195 CYS 195 195 195 CYS CYS L . n 
C 3 196 GLU 196 196 196 GLU GLU L . n 
C 3 197 VAL 197 197 197 VAL VAL L . n 
C 3 198 THR 198 198 198 THR THR L . n 
C 3 199 HIS 199 199 199 HIS HIS L . n 
C 3 200 GLN 200 200 200 GLN GLN L . n 
C 3 201 GLY 201 201 201 GLY GLY L . n 
C 3 202 LEU 202 202 202 LEU LEU L . n 
C 3 203 SER 203 203 203 SER SER L . n 
C 3 204 SER 204 204 204 SER SER L . n 
C 3 205 PRO 205 205 205 PRO PRO L . n 
C 3 206 VAL 206 206 206 VAL VAL L . n 
C 3 207 THR 207 207 207 THR THR L . n 
C 3 208 LYS 208 208 208 LYS LYS L . n 
C 3 209 SER 209 209 209 SER SER L . n 
C 3 210 PHE 210 210 210 PHE PHE L . n 
C 3 211 ASN 211 211 211 ASN ASN L . n 
C 3 212 ARG 212 212 212 ARG ARG L . n 
C 3 213 GLY 213 213 213 GLY GLY L . n 
C 3 214 GLU 214 214 ?   ?   ?   L . n 
C 3 215 CYS 215 215 ?   ?   ?   L . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
D 4 NAG 1 B NAG 1 B NAG 1 n 
D 4 NAG 2 B NAG 2 B NAG 2 n 
D 4 BMA 3 B BMA 3 B BMA 3 n 
D 4 FUC 4 B FUC 4 B FUC 4 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 5 HOH 1   201 27  HOH HOH A . 
E 5 HOH 2   202 435 HOH HOH A . 
E 5 HOH 3   203 124 HOH HOH A . 
E 5 HOH 4   204 438 HOH HOH A . 
E 5 HOH 5   205 202 HOH HOH A . 
E 5 HOH 6   206 340 HOH HOH A . 
E 5 HOH 7   207 146 HOH HOH A . 
E 5 HOH 8   208 274 HOH HOH A . 
E 5 HOH 9   209 268 HOH HOH A . 
E 5 HOH 10  210 205 HOH HOH A . 
E 5 HOH 11  211 159 HOH HOH A . 
E 5 HOH 12  212 14  HOH HOH A . 
E 5 HOH 13  213 293 HOH HOH A . 
E 5 HOH 14  214 257 HOH HOH A . 
E 5 HOH 15  215 354 HOH HOH A . 
E 5 HOH 16  216 163 HOH HOH A . 
E 5 HOH 17  217 467 HOH HOH A . 
E 5 HOH 18  218 185 HOH HOH A . 
E 5 HOH 19  219 143 HOH HOH A . 
E 5 HOH 20  220 360 HOH HOH A . 
E 5 HOH 21  221 2   HOH HOH A . 
E 5 HOH 22  222 107 HOH HOH A . 
E 5 HOH 23  223 26  HOH HOH A . 
E 5 HOH 24  224 454 HOH HOH A . 
E 5 HOH 25  225 8   HOH HOH A . 
E 5 HOH 26  226 308 HOH HOH A . 
E 5 HOH 27  227 333 HOH HOH A . 
E 5 HOH 28  228 326 HOH HOH A . 
E 5 HOH 29  229 109 HOH HOH A . 
E 5 HOH 30  230 29  HOH HOH A . 
E 5 HOH 31  231 80  HOH HOH A . 
E 5 HOH 32  232 47  HOH HOH A . 
E 5 HOH 33  233 60  HOH HOH A . 
E 5 HOH 34  234 1   HOH HOH A . 
E 5 HOH 35  235 395 HOH HOH A . 
E 5 HOH 36  236 197 HOH HOH A . 
E 5 HOH 37  237 112 HOH HOH A . 
E 5 HOH 38  238 539 HOH HOH A . 
E 5 HOH 39  239 19  HOH HOH A . 
E 5 HOH 40  240 256 HOH HOH A . 
E 5 HOH 41  241 18  HOH HOH A . 
E 5 HOH 42  242 20  HOH HOH A . 
E 5 HOH 43  243 230 HOH HOH A . 
E 5 HOH 44  244 217 HOH HOH A . 
E 5 HOH 45  245 168 HOH HOH A . 
E 5 HOH 46  246 164 HOH HOH A . 
E 5 HOH 47  247 194 HOH HOH A . 
E 5 HOH 48  248 232 HOH HOH A . 
E 5 HOH 49  249 162 HOH HOH A . 
E 5 HOH 50  250 153 HOH HOH A . 
E 5 HOH 51  251 386 HOH HOH A . 
E 5 HOH 52  252 440 HOH HOH A . 
E 5 HOH 53  253 575 HOH HOH A . 
E 5 HOH 54  254 437 HOH HOH A . 
E 5 HOH 55  255 392 HOH HOH A . 
E 5 HOH 56  256 262 HOH HOH A . 
E 5 HOH 57  257 432 HOH HOH A . 
E 5 HOH 58  258 280 HOH HOH A . 
E 5 HOH 59  259 306 HOH HOH A . 
E 5 HOH 60  260 231 HOH HOH A . 
E 5 HOH 61  261 287 HOH HOH A . 
E 5 HOH 62  262 347 HOH HOH A . 
E 5 HOH 63  263 294 HOH HOH A . 
E 5 HOH 64  264 453 HOH HOH A . 
F 5 HOH 1   301 174 HOH HOH H . 
F 5 HOH 2   302 445 HOH HOH H . 
F 5 HOH 3   303 121 HOH HOH H . 
F 5 HOH 4   304 42  HOH HOH H . 
F 5 HOH 5   305 221 HOH HOH H . 
F 5 HOH 6   306 181 HOH HOH H . 
F 5 HOH 7   307 126 HOH HOH H . 
F 5 HOH 8   308 92  HOH HOH H . 
F 5 HOH 9   309 296 HOH HOH H . 
F 5 HOH 10  310 59  HOH HOH H . 
F 5 HOH 11  311 204 HOH HOH H . 
F 5 HOH 12  312 184 HOH HOH H . 
F 5 HOH 13  313 350 HOH HOH H . 
F 5 HOH 14  314 272 HOH HOH H . 
F 5 HOH 15  315 285 HOH HOH H . 
F 5 HOH 16  316 219 HOH HOH H . 
F 5 HOH 17  317 43  HOH HOH H . 
F 5 HOH 18  318 384 HOH HOH H . 
F 5 HOH 19  319 161 HOH HOH H . 
F 5 HOH 20  320 70  HOH HOH H . 
F 5 HOH 21  321 73  HOH HOH H . 
F 5 HOH 22  322 158 HOH HOH H . 
F 5 HOH 23  323 58  HOH HOH H . 
F 5 HOH 24  324 116 HOH HOH H . 
F 5 HOH 25  325 48  HOH HOH H . 
F 5 HOH 26  326 118 HOH HOH H . 
F 5 HOH 27  327 200 HOH HOH H . 
F 5 HOH 28  328 120 HOH HOH H . 
F 5 HOH 29  329 171 HOH HOH H . 
F 5 HOH 30  330 86  HOH HOH H . 
F 5 HOH 31  331 114 HOH HOH H . 
F 5 HOH 32  332 131 HOH HOH H . 
F 5 HOH 33  333 100 HOH HOH H . 
F 5 HOH 34  334 65  HOH HOH H . 
F 5 HOH 35  335 433 HOH HOH H . 
F 5 HOH 36  336 227 HOH HOH H . 
F 5 HOH 37  337 318 HOH HOH H . 
F 5 HOH 38  338 270 HOH HOH H . 
F 5 HOH 39  339 150 HOH HOH H . 
F 5 HOH 40  340 36  HOH HOH H . 
F 5 HOH 41  341 199 HOH HOH H . 
F 5 HOH 42  342 578 HOH HOH H . 
F 5 HOH 43  343 297 HOH HOH H . 
F 5 HOH 44  344 16  HOH HOH H . 
F 5 HOH 45  345 247 HOH HOH H . 
F 5 HOH 46  346 214 HOH HOH H . 
F 5 HOH 47  347 233 HOH HOH H . 
F 5 HOH 48  348 133 HOH HOH H . 
F 5 HOH 49  349 117 HOH HOH H . 
F 5 HOH 50  350 223 HOH HOH H . 
F 5 HOH 51  351 111 HOH HOH H . 
F 5 HOH 52  352 38  HOH HOH H . 
F 5 HOH 53  353 140 HOH HOH H . 
F 5 HOH 54  354 364 HOH HOH H . 
F 5 HOH 55  355 358 HOH HOH H . 
F 5 HOH 56  356 3   HOH HOH H . 
F 5 HOH 57  357 335 HOH HOH H . 
F 5 HOH 58  358 144 HOH HOH H . 
F 5 HOH 59  359 105 HOH HOH H . 
F 5 HOH 60  360 320 HOH HOH H . 
F 5 HOH 61  361 110 HOH HOH H . 
F 5 HOH 62  362 295 HOH HOH H . 
F 5 HOH 63  363 286 HOH HOH H . 
F 5 HOH 64  364 145 HOH HOH H . 
F 5 HOH 65  365 380 HOH HOH H . 
F 5 HOH 66  366 436 HOH HOH H . 
F 5 HOH 67  367 56  HOH HOH H . 
F 5 HOH 68  368 93  HOH HOH H . 
F 5 HOH 69  369 97  HOH HOH H . 
F 5 HOH 70  370 571 HOH HOH H . 
F 5 HOH 71  371 119 HOH HOH H . 
F 5 HOH 72  372 198 HOH HOH H . 
F 5 HOH 73  373 172 HOH HOH H . 
F 5 HOH 74  374 101 HOH HOH H . 
F 5 HOH 75  375 291 HOH HOH H . 
F 5 HOH 76  376 183 HOH HOH H . 
F 5 HOH 77  377 212 HOH HOH H . 
F 5 HOH 78  378 419 HOH HOH H . 
F 5 HOH 79  379 52  HOH HOH H . 
F 5 HOH 80  380 147 HOH HOH H . 
F 5 HOH 81  381 203 HOH HOH H . 
F 5 HOH 82  382 236 HOH HOH H . 
F 5 HOH 83  383 142 HOH HOH H . 
F 5 HOH 84  384 193 HOH HOH H . 
F 5 HOH 85  385 160 HOH HOH H . 
F 5 HOH 86  386 106 HOH HOH H . 
F 5 HOH 87  387 11  HOH HOH H . 
F 5 HOH 88  388 148 HOH HOH H . 
F 5 HOH 89  389 79  HOH HOH H . 
F 5 HOH 90  390 372 HOH HOH H . 
F 5 HOH 91  391 401 HOH HOH H . 
F 5 HOH 92  392 243 HOH HOH H . 
F 5 HOH 93  393 434 HOH HOH H . 
F 5 HOH 94  394 701 HOH HOH H . 
F 5 HOH 95  395 89  HOH HOH H . 
F 5 HOH 96  396 191 HOH HOH H . 
F 5 HOH 97  397 71  HOH HOH H . 
F 5 HOH 98  398 213 HOH HOH H . 
F 5 HOH 99  399 245 HOH HOH H . 
F 5 HOH 100 400 35  HOH HOH H . 
F 5 HOH 101 401 369 HOH HOH H . 
F 5 HOH 102 402 235 HOH HOH H . 
F 5 HOH 103 403 576 HOH HOH H . 
F 5 HOH 104 404 41  HOH HOH H . 
F 5 HOH 105 405 44  HOH HOH H . 
F 5 HOH 106 406 255 HOH HOH H . 
F 5 HOH 107 407 149 HOH HOH H . 
F 5 HOH 108 408 179 HOH HOH H . 
F 5 HOH 109 409 40  HOH HOH H . 
F 5 HOH 110 410 64  HOH HOH H . 
F 5 HOH 111 411 141 HOH HOH H . 
F 5 HOH 112 412 209 HOH HOH H . 
F 5 HOH 113 413 188 HOH HOH H . 
F 5 HOH 114 414 180 HOH HOH H . 
F 5 HOH 115 415 444 HOH HOH H . 
F 5 HOH 116 416 521 HOH HOH H . 
F 5 HOH 117 417 375 HOH HOH H . 
F 5 HOH 118 418 224 HOH HOH H . 
F 5 HOH 119 419 429 HOH HOH H . 
F 5 HOH 120 420 328 HOH HOH H . 
F 5 HOH 121 421 260 HOH HOH H . 
F 5 HOH 122 422 316 HOH HOH H . 
F 5 HOH 123 423 49  HOH HOH H . 
F 5 HOH 124 424 170 HOH HOH H . 
F 5 HOH 125 425 399 HOH HOH H . 
F 5 HOH 126 426 317 HOH HOH H . 
F 5 HOH 127 427 439 HOH HOH H . 
F 5 HOH 128 428 423 HOH HOH H . 
F 5 HOH 129 429 249 HOH HOH H . 
F 5 HOH 130 430 313 HOH HOH H . 
F 5 HOH 131 431 136 HOH HOH H . 
F 5 HOH 132 432 215 HOH HOH H . 
F 5 HOH 133 433 331 HOH HOH H . 
F 5 HOH 134 434 516 HOH HOH H . 
F 5 HOH 135 435 182 HOH HOH H . 
F 5 HOH 136 436 314 HOH HOH H . 
F 5 HOH 137 437 329 HOH HOH H . 
F 5 HOH 138 438 238 HOH HOH H . 
F 5 HOH 139 439 177 HOH HOH H . 
F 5 HOH 140 440 208 HOH HOH H . 
F 5 HOH 141 441 154 HOH HOH H . 
F 5 HOH 142 442 319 HOH HOH H . 
F 5 HOH 143 443 104 HOH HOH H . 
F 5 HOH 144 444 290 HOH HOH H . 
F 5 HOH 145 445 244 HOH HOH H . 
F 5 HOH 146 446 94  HOH HOH H . 
F 5 HOH 147 447 165 HOH HOH H . 
F 5 HOH 148 448 344 HOH HOH H . 
F 5 HOH 149 449 298 HOH HOH H . 
F 5 HOH 150 450 99  HOH HOH H . 
F 5 HOH 151 451 186 HOH HOH H . 
F 5 HOH 152 452 155 HOH HOH H . 
F 5 HOH 153 453 63  HOH HOH H . 
F 5 HOH 154 454 241 HOH HOH H . 
G 5 HOH 1   301 345 HOH HOH L . 
G 5 HOH 2   302 157 HOH HOH L . 
G 5 HOH 3   303 376 HOH HOH L . 
G 5 HOH 4   304 25  HOH HOH L . 
G 5 HOH 5   305 382 HOH HOH L . 
G 5 HOH 6   306 78  HOH HOH L . 
G 5 HOH 7   307 151 HOH HOH L . 
G 5 HOH 8   308 139 HOH HOH L . 
G 5 HOH 9   309 187 HOH HOH L . 
G 5 HOH 10  310 53  HOH HOH L . 
G 5 HOH 11  311 85  HOH HOH L . 
G 5 HOH 12  312 264 HOH HOH L . 
G 5 HOH 13  313 353 HOH HOH L . 
G 5 HOH 14  314 90  HOH HOH L . 
G 5 HOH 15  315 201 HOH HOH L . 
G 5 HOH 16  316 24  HOH HOH L . 
G 5 HOH 17  317 10  HOH HOH L . 
G 5 HOH 18  318 211 HOH HOH L . 
G 5 HOH 19  319 98  HOH HOH L . 
G 5 HOH 20  320 229 HOH HOH L . 
G 5 HOH 21  321 398 HOH HOH L . 
G 5 HOH 22  322 50  HOH HOH L . 
G 5 HOH 23  323 115 HOH HOH L . 
G 5 HOH 24  324 366 HOH HOH L . 
G 5 HOH 25  325 271 HOH HOH L . 
G 5 HOH 26  326 173 HOH HOH L . 
G 5 HOH 27  327 378 HOH HOH L . 
G 5 HOH 28  328 66  HOH HOH L . 
G 5 HOH 29  329 87  HOH HOH L . 
G 5 HOH 30  330 55  HOH HOH L . 
G 5 HOH 31  331 81  HOH HOH L . 
G 5 HOH 32  332 12  HOH HOH L . 
G 5 HOH 33  333 332 HOH HOH L . 
G 5 HOH 34  334 304 HOH HOH L . 
G 5 HOH 35  335 91  HOH HOH L . 
G 5 HOH 36  336 39  HOH HOH L . 
G 5 HOH 37  337 74  HOH HOH L . 
G 5 HOH 38  338 407 HOH HOH L . 
G 5 HOH 39  339 178 HOH HOH L . 
G 5 HOH 40  340 33  HOH HOH L . 
G 5 HOH 41  341 341 HOH HOH L . 
G 5 HOH 42  342 72  HOH HOH L . 
G 5 HOH 43  343 265 HOH HOH L . 
G 5 HOH 44  344 31  HOH HOH L . 
G 5 HOH 45  345 88  HOH HOH L . 
G 5 HOH 46  346 305 HOH HOH L . 
G 5 HOH 47  347 62  HOH HOH L . 
G 5 HOH 48  348 577 HOH HOH L . 
G 5 HOH 49  349 250 HOH HOH L . 
G 5 HOH 50  350 309 HOH HOH L . 
G 5 HOH 51  351 7   HOH HOH L . 
G 5 HOH 52  352 210 HOH HOH L . 
G 5 HOH 53  353 9   HOH HOH L . 
G 5 HOH 54  354 342 HOH HOH L . 
G 5 HOH 55  355 237 HOH HOH L . 
G 5 HOH 56  356 122 HOH HOH L . 
G 5 HOH 57  357 130 HOH HOH L . 
G 5 HOH 58  358 196 HOH HOH L . 
G 5 HOH 59  359 37  HOH HOH L . 
G 5 HOH 60  360 225 HOH HOH L . 
G 5 HOH 61  361 95  HOH HOH L . 
G 5 HOH 62  362 23  HOH HOH L . 
G 5 HOH 63  363 75  HOH HOH L . 
G 5 HOH 64  364 21  HOH HOH L . 
G 5 HOH 65  365 77  HOH HOH L . 
G 5 HOH 66  366 137 HOH HOH L . 
G 5 HOH 67  367 568 HOH HOH L . 
G 5 HOH 68  368 581 HOH HOH L . 
G 5 HOH 69  369 45  HOH HOH L . 
G 5 HOH 70  370 127 HOH HOH L . 
G 5 HOH 71  371 397 HOH HOH L . 
G 5 HOH 72  372 254 HOH HOH L . 
G 5 HOH 73  373 337 HOH HOH L . 
G 5 HOH 74  374 22  HOH HOH L . 
G 5 HOH 75  375 113 HOH HOH L . 
G 5 HOH 76  376 357 HOH HOH L . 
G 5 HOH 77  377 525 HOH HOH L . 
G 5 HOH 78  378 248 HOH HOH L . 
G 5 HOH 79  379 30  HOH HOH L . 
G 5 HOH 80  380 83  HOH HOH L . 
G 5 HOH 81  381 125 HOH HOH L . 
G 5 HOH 82  382 132 HOH HOH L . 
G 5 HOH 83  383 526 HOH HOH L . 
G 5 HOH 84  384 108 HOH HOH L . 
G 5 HOH 85  385 68  HOH HOH L . 
G 5 HOH 86  386 54  HOH HOH L . 
G 5 HOH 87  387 303 HOH HOH L . 
G 5 HOH 88  388 84  HOH HOH L . 
G 5 HOH 89  389 371 HOH HOH L . 
G 5 HOH 90  390 6   HOH HOH L . 
G 5 HOH 91  391 135 HOH HOH L . 
G 5 HOH 92  392 15  HOH HOH L . 
G 5 HOH 93  393 61  HOH HOH L . 
G 5 HOH 94  394 4   HOH HOH L . 
G 5 HOH 95  395 278 HOH HOH L . 
G 5 HOH 96  396 267 HOH HOH L . 
G 5 HOH 97  397 315 HOH HOH L . 
G 5 HOH 98  398 463 HOH HOH L . 
G 5 HOH 99  399 17  HOH HOH L . 
G 5 HOH 100 400 67  HOH HOH L . 
G 5 HOH 101 401 520 HOH HOH L . 
G 5 HOH 102 402 301 HOH HOH L . 
G 5 HOH 103 403 242 HOH HOH L . 
G 5 HOH 104 404 46  HOH HOH L . 
G 5 HOH 105 405 258 HOH HOH L . 
G 5 HOH 106 406 425 HOH HOH L . 
G 5 HOH 107 407 34  HOH HOH L . 
G 5 HOH 108 408 312 HOH HOH L . 
G 5 HOH 109 409 261 HOH HOH L . 
G 5 HOH 110 410 152 HOH HOH L . 
G 5 HOH 111 411 273 HOH HOH L . 
G 5 HOH 112 412 96  HOH HOH L . 
G 5 HOH 113 413 13  HOH HOH L . 
G 5 HOH 114 414 156 HOH HOH L . 
G 5 HOH 115 415 299 HOH HOH L . 
G 5 HOH 116 416 283 HOH HOH L . 
G 5 HOH 117 417 334 HOH HOH L . 
G 5 HOH 118 418 400 HOH HOH L . 
G 5 HOH 119 419 192 HOH HOH L . 
G 5 HOH 120 420 102 HOH HOH L . 
G 5 HOH 121 421 69  HOH HOH L . 
G 5 HOH 122 422 28  HOH HOH L . 
G 5 HOH 123 423 490 HOH HOH L . 
G 5 HOH 124 424 51  HOH HOH L . 
G 5 HOH 125 425 403 HOH HOH L . 
G 5 HOH 126 426 391 HOH HOH L . 
G 5 HOH 127 427 338 HOH HOH L . 
G 5 HOH 128 428 5   HOH HOH L . 
G 5 HOH 129 429 129 HOH HOH L . 
G 5 HOH 130 430 582 HOH HOH L . 
G 5 HOH 131 431 351 HOH HOH L . 
G 5 HOH 132 432 175 HOH HOH L . 
G 5 HOH 133 433 373 HOH HOH L . 
G 5 HOH 134 434 32  HOH HOH L . 
G 5 HOH 135 435 514 HOH HOH L . 
G 5 HOH 136 436 222 HOH HOH L . 
G 5 HOH 137 437 472 HOH HOH L . 
G 5 HOH 138 438 421 HOH HOH L . 
G 5 HOH 139 439 346 HOH HOH L . 
G 5 HOH 140 440 128 HOH HOH L . 
G 5 HOH 141 441 327 HOH HOH L . 
G 5 HOH 142 442 406 HOH HOH L . 
G 5 HOH 143 443 570 HOH HOH L . 
G 5 HOH 144 444 523 HOH HOH L . 
G 5 HOH 145 445 284 HOH HOH L . 
G 5 HOH 146 446 361 HOH HOH L . 
G 5 HOH 147 447 253 HOH HOH L . 
G 5 HOH 148 448 517 HOH HOH L . 
G 5 HOH 149 449 189 HOH HOH L . 
G 5 HOH 150 450 534 HOH HOH L . 
G 5 HOH 151 451 443 HOH HOH L . 
G 5 HOH 152 452 292 HOH HOH L . 
G 5 HOH 153 453 269 HOH HOH L . 
G 5 HOH 154 454 206 HOH HOH L . 
G 5 HOH 155 455 430 HOH HOH L . 
G 5 HOH 156 456 239 HOH HOH L . 
G 5 HOH 157 457 218 HOH HOH L . 
G 5 HOH 158 458 76  HOH HOH L . 
G 5 HOH 159 459 377 HOH HOH L . 
G 5 HOH 160 460 569 HOH HOH L . 
G 5 HOH 161 461 442 HOH HOH L . 
G 5 HOH 162 462 138 HOH HOH L . 
G 5 HOH 163 463 134 HOH HOH L . 
G 5 HOH 164 464 266 HOH HOH L . 
G 5 HOH 165 465 390 HOH HOH L . 
G 5 HOH 166 466 300 HOH HOH L . 
G 5 HOH 167 467 216 HOH HOH L . 
G 5 HOH 168 468 82  HOH HOH L . 
G 5 HOH 169 469 452 HOH HOH L . 
G 5 HOH 170 470 103 HOH HOH L . 
G 5 HOH 171 471 441 HOH HOH L . 
G 5 HOH 172 472 289 HOH HOH L . 
G 5 HOH 173 473 324 HOH HOH L . 
G 5 HOH 174 474 57  HOH HOH L . 
G 5 HOH 175 475 515 HOH HOH L . 
G 5 HOH 176 476 123 HOH HOH L . 
G 5 HOH 177 477 226 HOH HOH L . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 22  ? CG  ? A GLU 24  CG  
2  1 Y 1 A GLU 22  ? CD  ? A GLU 24  CD  
3  1 Y 1 A GLU 22  ? OE1 ? A GLU 24  OE1 
4  1 Y 1 A GLU 22  ? OE2 ? A GLU 24  OE2 
5  1 Y 1 A GLN 80  ? CG  ? A GLN 82  CG  
6  1 Y 1 A GLN 80  ? CD  ? A GLN 82  CD  
7  1 Y 1 A GLN 80  ? OE1 ? A GLN 82  OE1 
8  1 Y 1 A GLN 80  ? NE2 ? A GLN 82  NE2 
9  1 Y 1 H GLN 1   ? CG  ? B GLN 1   CG  
10 1 Y 1 H GLN 1   ? CD  ? B GLN 1   CD  
11 1 Y 1 H GLN 1   ? OE1 ? B GLN 1   OE1 
12 1 Y 1 H GLN 1   ? NE2 ? B GLN 1   NE2 
13 1 Y 1 H GLN 3   ? CG  ? B GLN 3   CG  
14 1 Y 1 H GLN 3   ? CD  ? B GLN 3   CD  
15 1 Y 1 H GLN 3   ? OE1 ? B GLN 3   OE1 
16 1 Y 1 H GLN 3   ? NE2 ? B GLN 3   NE2 
17 1 Y 1 H ARG 16  ? CG  ? B ARG 16  CG  
18 1 Y 1 H ARG 16  ? CD  ? B ARG 16  CD  
19 1 Y 1 H ARG 16  ? NE  ? B ARG 16  NE  
20 1 Y 1 H ARG 16  ? CZ  ? B ARG 16  CZ  
21 1 Y 1 H ARG 16  ? NH1 ? B ARG 16  NH1 
22 1 Y 1 H ARG 16  ? NH2 ? B ARG 16  NH2 
23 1 Y 1 H LYS 43  ? CD  ? B LYS 43  CD  
24 1 Y 1 H LYS 43  ? CE  ? B LYS 43  CE  
25 1 Y 1 H LYS 43  ? NZ  ? B LYS 43  NZ  
26 1 Y 1 H LYS 65  ? CG  ? B LYS 65  CG  
27 1 Y 1 H LYS 65  ? CD  ? B LYS 65  CD  
28 1 Y 1 H LYS 65  ? CE  ? B LYS 65  CE  
29 1 Y 1 H LYS 65  ? NZ  ? B LYS 65  NZ  
30 1 Y 1 H LYS 76  ? NZ  ? B LYS 76  NZ  
31 1 Y 1 H GLN 110 ? CG  ? B GLN 110 CG  
32 1 Y 1 H GLN 110 ? CD  ? B GLN 110 CD  
33 1 Y 1 H GLN 110 ? OE1 ? B GLN 110 OE1 
34 1 Y 1 H GLN 110 ? NE2 ? B GLN 110 NE2 
35 1 Y 1 H SER 117 ? OG  ? B SER 117 OG  
36 1 Y 1 H LYS 122 ? CE  ? B LYS 122 CE  
37 1 Y 1 H LYS 122 ? NZ  ? B LYS 122 NZ  
38 1 Y 1 H LYS 214 ? CE  ? B LYS 214 CE  
39 1 Y 1 H LYS 214 ? NZ  ? B LYS 214 NZ  
40 1 Y 1 L ARG 46  ? CG  ? C ARG 46  CG  
41 1 Y 1 L ARG 46  ? CD  ? C ARG 46  CD  
42 1 Y 1 L ARG 46  ? NE  ? C ARG 46  NE  
43 1 Y 1 L ARG 46  ? CZ  ? C ARG 46  CZ  
44 1 Y 1 L ARG 46  ? NH1 ? C ARG 46  NH1 
45 1 Y 1 L ARG 46  ? NH2 ? C ARG 46  NH2 
46 1 Y 1 L GLU 124 ? OE1 ? C GLU 124 OE1 
47 1 Y 1 L GLU 124 ? OE2 ? C GLU 124 OE2 
48 1 Y 1 L LYS 146 ? CG  ? C LYS 146 CG  
49 1 Y 1 L LYS 146 ? CD  ? C LYS 146 CD  
50 1 Y 1 L LYS 146 ? CE  ? C LYS 146 CE  
51 1 Y 1 L LYS 146 ? NZ  ? C LYS 146 NZ  
52 1 Y 1 L GLN 148 ? CG  ? C GLN 148 CG  
53 1 Y 1 L GLN 148 ? CD  ? C GLN 148 CD  
54 1 Y 1 L GLN 148 ? OE1 ? C GLN 148 OE1 
55 1 Y 1 L GLN 148 ? NE2 ? C GLN 148 NE2 
56 1 Y 1 L ASN 153 ? CG  ? C ASN 153 CG  
57 1 Y 1 L ASN 153 ? OD1 ? C ASN 153 OD1 
58 1 Y 1 L ASN 153 ? ND2 ? C ASN 153 ND2 
59 1 Y 1 L LYS 170 ? CG  ? C LYS 170 CG  
60 1 Y 1 L LYS 170 ? CD  ? C LYS 170 CD  
61 1 Y 1 L LYS 170 ? CE  ? C LYS 170 CE  
62 1 Y 1 L LYS 170 ? NZ  ? C LYS 170 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? '(1.20.1_4487: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DQ4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     82.314 
_cell.length_a_esd                 ? 
_cell.length_b                     152.778 
_cell.length_b_esd                 ? 
_cell.length_c                     48.012 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DQ4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                18 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DQ4 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.43 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.29 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.25 M sodium acetate trihydrate, 25% PEG3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            300 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-10-05 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 17-ID' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   17-ID 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9DQ4 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.57 
_reflns.d_resolution_low                               82.163 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     68048 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           86.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.2 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.139 
_reflns.pdbx_Rpim_I_all                                0.057 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.126 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.57 
_reflns_shell.d_res_low                                     1.946 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2337 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               3.2 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.797 
_reflns_shell.pdbx_Rpim_I_all                               0.416 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.675 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9DQ4 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.57 
_refine.ls_d_res_low                             40.02 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     68048 
_refine.ls_number_reflns_R_free                  3449 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    78.90 
_refine.ls_percent_reflns_R_free                 5.07 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2062 
_refine.ls_R_factor_R_free                       0.2329 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2048 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.38 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.86 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.17 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        4034 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         49 
_refine_hist.number_atoms_solvent             395 
_refine_hist.number_atoms_total               4478 
_refine_hist.d_res_high                       1.57 
_refine_hist.d_res_low                        40.02 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012  ? ?    ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.257  ? ?    ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 15.109 ? 1477 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.075  ? 659  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.011  ? 723  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.57 1.59  . . 22  401  12.00  . . . . 0.2509 . . . . . . . . . . . 0.2847 
'X-RAY DIFFRACTION' 1.59 1.61  . . 31  578  18.00  . . . . 0.2477 . . . . . . . . . . . 0.2505 
'X-RAY DIFFRACTION' 1.61 1.63  . . 44  911  28.00  . . . . 0.2561 . . . . . . . . . . . 0.3069 
'X-RAY DIFFRACTION' 1.63 1.66  . . 58  1202 37.00  . . . . 0.2498 . . . . . . . . . . . 0.2791 
'X-RAY DIFFRACTION' 1.66 1.69  . . 83  1543 48.00  . . . . 0.2482 . . . . . . . . . . . 0.2686 
'X-RAY DIFFRACTION' 1.69 1.71  . . 106 1985 61.00  . . . . 0.2544 . . . . . . . . . . . 0.2784 
'X-RAY DIFFRACTION' 1.71 1.75  . . 139 2483 78.00  . . . . 0.2567 . . . . . . . . . . . 0.2794 
'X-RAY DIFFRACTION' 1.75 1.78  . . 156 2858 87.00  . . . . 0.2475 . . . . . . . . . . . 0.2474 
'X-RAY DIFFRACTION' 1.78 1.82  . . 157 3125 98.00  . . . . 0.2484 . . . . . . . . . . . 0.2802 
'X-RAY DIFFRACTION' 1.82 1.86  . . 170 3259 100.00 . . . . 0.2422 . . . . . . . . . . . 0.2726 
'X-RAY DIFFRACTION' 1.86 1.90  . . 168 3241 100.00 . . . . 0.2260 . . . . . . . . . . . 0.2525 
'X-RAY DIFFRACTION' 1.90 1.95  . . 93  2516 76.00  . . . . 0.2239 . . . . . . . . . . . 0.2901 
'X-RAY DIFFRACTION' 1.95 2.00  . . 140 3295 100.00 . . . . 0.2113 . . . . . . . . . . . 0.2677 
'X-RAY DIFFRACTION' 2.00 2.05  . . 181 2992 99.00  . . . . 0.2118 . . . . . . . . . . . 0.2209 
'X-RAY DIFFRACTION' 2.08 2.12  . . 118 2261 98.00  . . . . 0.2082 . . . . . . . . . . . 0.2605 
'X-RAY DIFFRACTION' 2.12 2.20  . . 200 3232 100.00 . . . . 0.2045 . . . . . . . . . . . 0.2588 
'X-RAY DIFFRACTION' 2.20 2.29  . . 117 2399 73.00  . . . . 0.2174 . . . . . . . . . . . 0.2388 
'X-RAY DIFFRACTION' 2.29 2.39  . . 155 3265 99.00  . . . . 0.2074 . . . . . . . . . . . 0.2589 
'X-RAY DIFFRACTION' 2.39 2.52  . . 175 3256 99.00  . . . . 0.2066 . . . . . . . . . . . 0.2309 
'X-RAY DIFFRACTION' 2.52 2.68  . . 179 3263 99.00  . . . . 0.2116 . . . . . . . . . . . 0.2250 
'X-RAY DIFFRACTION' 2.68 2.88  . . 198 3218 99.00  . . . . 0.2156 . . . . . . . . . . . 0.2388 
'X-RAY DIFFRACTION' 2.88 3.17  . . 175 3289 99.00  . . . . 0.2103 . . . . . . . . . . . 0.2409 
'X-RAY DIFFRACTION' 3.17 3.63  . . 205 3235 98.00  . . . . 0.1962 . . . . . . . . . . . 0.2246 
'X-RAY DIFFRACTION' 3.63 4.57  . . 191 3301 98.00  . . . . 0.1649 . . . . . . . . . . . 0.1812 
'X-RAY DIFFRACTION' 4.57 40.02 . . 188 3491 99.00  . . . . 0.1876 . . . . . . . . . . . 0.2205 
# 
_struct.entry_id                     9DQ4 
_struct.title                        'Crystal structure of engineered Ipilimumab (mipi.4) Fab in complex with mouse CTLA-4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DQ4 
_struct_keywords.text            'Antibody, CTLA-4, ANTITUMOR PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'ANTITUMOR PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
G N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CTLA4_MOUSE P09793 ? 1 
;EAIQVTQPSVVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPFCSGTFNESRVNLT
IQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTQIYVID
;
36 
2 PDB 9DQ4        9DQ4   ? 2 ? 1  
3 PDB 9DQ4        9DQ4   ? 3 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9DQ4 A 1 ? 118 ? P09793 36 ? 153 ? -1 116 
2 2 9DQ4 H 1 ? 229 ? 9DQ4   1  ? 229 ? 1  229 
3 3 9DQ4 L 1 ? 215 ? 9DQ4   1  ? 215 ? 1  215 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9DQ4 GLY A 119 ? UNP P09793 ? ? 'expression tag' 117 1 
1 9DQ4 HIS A 120 ? UNP P09793 ? ? 'expression tag' 118 2 
1 9DQ4 HIS A 121 ? UNP P09793 ? ? 'expression tag' 119 3 
1 9DQ4 HIS A 122 ? UNP P09793 ? ? 'expression tag' 120 4 
1 9DQ4 HIS A 123 ? UNP P09793 ? ? 'expression tag' 121 5 
1 9DQ4 HIS A 124 ? UNP P09793 ? ? 'expression tag' 122 6 
1 9DQ4 HIS A 125 ? UNP P09793 ? ? 'expression tag' 123 7 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 5700  ? 
1 MORE         -22   ? 
1 'SSA (A^2)'  23870 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
loop_
_pdbx_struct_assembly_auth_evidence.id 
_pdbx_struct_assembly_auth_evidence.assembly_id 
_pdbx_struct_assembly_auth_evidence.experimental_support 
_pdbx_struct_assembly_auth_evidence.details 
1 1 'surface plasmon resonance' ? 
2 1 'gel filtration'            ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ARG A 85  ? THR A 89  ? ARG A 83  THR A 87  5 ? 5 
HELX_P HELX_P2 AA2 THR B 28  ? TYR B 32  ? THR H 28  TYR H 32  5 ? 5 
HELX_P HELX_P3 AA3 ARG B 87  ? THR B 91  ? ARG H 87  THR H 91  5 ? 5 
HELX_P HELX_P4 AA4 SER B 161 ? ALA B 163 ? SER H 161 ALA H 163 5 ? 3 
HELX_P HELX_P5 AA5 SER B 192 ? GLY B 195 ? SER H 192 GLY H 195 5 ? 4 
HELX_P HELX_P6 AA6 LYS B 206 ? ASN B 209 ? LYS H 206 ASN H 209 5 ? 4 
HELX_P HELX_P7 AA7 GLU C 80  ? PHE C 84  ? GLU L 80  PHE L 84  5 ? 5 
HELX_P HELX_P8 AA8 SER C 122 ? SER C 128 ? SER L 122 SER L 128 1 ? 7 
HELX_P HELX_P9 AA9 LYS C 184 ? HIS C 190 ? LYS L 184 HIS L 190 1 ? 7 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 23  SG  ? ? ? 1_555 A CYS 94  SG ? ? A CYS 21  A CYS 92  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf2 disulf ?    ? A CYS 50  SG  ? ? ? 1_555 A CYS 68  SG ? ? A CYS 48  A CYS 66  1_555 ? ? ? ? ? ? ? 2.066 ? ?               
disulf3 disulf ?    ? B CYS 22  SG  ? ? ? 1_555 B CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.061 ? ?               
disulf4 disulf ?    ? B CYS 145 SG  ? ? ? 1_555 B CYS 201 SG ? ? H CYS 145 H CYS 201 1_555 ? ? ? ? ? ? ? 2.025 ? ?               
disulf5 disulf ?    ? C CYS 23  SG  ? ? ? 1_555 C CYS 89  SG ? ? L CYS 23  L CYS 89  1_555 ? ? ? ? ? ? ? 2.112 ? ?               
disulf6 disulf ?    ? C CYS 135 SG  ? ? ? 1_555 C CYS 195 SG ? ? L CYS 135 L CYS 195 1_555 ? ? ? ? ? ? ? 2.014 ? ?               
covale1 covale one  ? A ASN 110 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 108 B NAG 1   1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale2 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? B NAG 1   B NAG 2   1_555 ? ? ? ? ? ? ? 1.426 ? ?               
covale3 covale both ? D NAG .   O6  ? ? ? 1_555 D FUC .   C1 ? ? B NAG 1   B FUC 4   1_555 ? ? ? ? ? ? ? 1.428 ? ?               
covale4 covale both ? D NAG .   O4  ? ? ? 1_555 D BMA .   C1 ? ? B NAG 2   B BMA 3   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG D .   ? ASN A 110 ? NAG B 1   ? 1_555 ASN A 108 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 CYS A 23  ? CYS A 94  ? CYS A 21  ? 1_555 CYS A 92  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
3 CYS A 50  ? CYS A 68  ? CYS A 48  ? 1_555 CYS A 66  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4 CYS B 22  ? CYS B 96  ? CYS H 22  ? 1_555 CYS H 96  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5 CYS B 145 ? CYS B 201 ? CYS H 145 ? 1_555 CYS H 201 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6 CYS C 23  ? CYS C 89  ? CYS L 23  ? 1_555 CYS L 89  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7 CYS C 135 ? CYS C 195 ? CYS L 135 ? 1_555 CYS L 195 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 26  A . ? SER 24  A PRO 27  A ? PRO 25  A 1 -5.15 
2 TYR 100 A . ? TYR 98  A PRO 101 A ? PRO 99  A 1 -0.38 
3 PRO 102 A . ? PRO 100 A PRO 103 A ? PRO 101 A 1 2.30  
4 PHE 151 B . ? PHE 151 H PRO 152 B ? PRO 152 H 1 -7.78 
5 GLU 153 B . ? GLU 153 H PRO 154 B ? PRO 154 H 1 5.20  
6 SER 7   C . ? SER 7   L PRO 8   C ? PRO 8   L 1 -7.98 
7 SER 95  C . ? SER 95  L PRO 96  C ? PRO 96  L 1 -7.37 
8 TYR 141 C . ? TYR 141 L PRO 142 C ? PRO 142 L 1 0.93  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 3 ? 
AB1 ? 4 ? 
AB2 ? 6 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB2 5 6 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 4   ? THR A 6   ? GLN A 2   THR A 4   
AA1 2 ALA A 19  ? SER A 26  ? ALA A 17  SER A 24  
AA1 3 ARG A 76  ? ILE A 81  ? ARG A 74  ILE A 79  
AA1 4 CYS A 68  ? ASN A 73  ? CYS A 66  ASN A 71  
AA2 1 VAL A 10  ? LEU A 12  ? VAL A 8   LEU A 10  
AA2 2 THR A 112 ? TYR A 115 ? THR A 110 TYR A 113 
AA2 3 GLY A 90  ? TYR A 100 ? GLY A 88  TYR A 98  
AA2 4 GLU A 33  ? ARG A 40  ? GLU A 31  ARG A 38  
AA2 5 THR A 47  ? PHE A 54  ? THR A 45  PHE A 52  
AA3 1 VAL A 10  ? LEU A 12  ? VAL A 8   LEU A 10  
AA3 2 THR A 112 ? TYR A 115 ? THR A 110 TYR A 113 
AA3 3 GLY A 90  ? TYR A 100 ? GLY A 88  TYR A 98  
AA3 4 PHE A 105 ? MET A 108 ? PHE A 103 MET A 106 
AA4 1 GLN B 3   ? SER B 7   ? GLN H 3   SER H 7   
AA4 2 LEU B 18  ? SER B 25  ? LEU H 18  SER H 25  
AA4 3 THR B 78  ? MET B 83  ? THR H 78  MET H 83  
AA4 4 PHE B 68  ? ASP B 73  ? PHE H 68  ASP H 73  
AA5 1 VAL B 11  ? VAL B 12  ? VAL H 11  VAL H 12  
AA5 2 THR B 112 ? VAL B 116 ? THR H 112 VAL H 116 
AA5 3 ALA B 92  ? THR B 99  ? ALA H 92  THR H 99  
AA5 4 MET B 34  ? GLN B 39  ? MET H 34  GLN H 39  
AA5 5 GLU B 46  ? ILE B 51  ? GLU H 46  ILE H 51  
AA5 6 LYS B 58  ? TYR B 60  ? LYS H 58  TYR H 60  
AA6 1 VAL B 11  ? VAL B 12  ? VAL H 11  VAL H 12  
AA6 2 THR B 112 ? VAL B 116 ? THR H 112 VAL H 116 
AA6 3 ALA B 92  ? THR B 99  ? ALA H 92  THR H 99  
AA6 4 PHE B 105 ? TRP B 108 ? PHE H 105 TRP H 108 
AA7 1 SER B 125 ? LEU B 129 ? SER H 125 LEU H 129 
AA7 2 THR B 140 ? TYR B 150 ? THR H 140 TYR H 150 
AA7 3 TYR B 181 ? PRO B 190 ? TYR H 181 PRO H 190 
AA7 4 VAL B 168 ? THR B 170 ? VAL H 168 THR H 170 
AA8 1 SER B 125 ? LEU B 129 ? SER H 125 LEU H 129 
AA8 2 THR B 140 ? TYR B 150 ? THR H 140 TYR H 150 
AA8 3 TYR B 181 ? PRO B 190 ? TYR H 181 PRO H 190 
AA8 4 VAL B 174 ? LEU B 175 ? VAL H 174 LEU H 175 
AA9 1 THR B 156 ? TRP B 159 ? THR H 156 TRP H 159 
AA9 2 ILE B 200 ? HIS B 205 ? ILE H 200 HIS H 205 
AA9 3 THR B 210 ? ARG B 215 ? THR H 210 ARG H 215 
AB1 1 LEU C 4   ? SER C 7   ? LEU L 4   SER L 7   
AB1 2 ALA C 19  ? GLN C 25  ? ALA L 19  GLN L 25  
AB1 3 ASP C 71  ? ILE C 76  ? ASP L 71  ILE L 76  
AB1 4 PHE C 63  ? SER C 68  ? PHE L 63  SER L 68  
AB2 1 THR C 10  ? LEU C 13  ? THR L 10  LEU L 13  
AB2 2 THR C 103 ? ILE C 107 ? THR L 103 ILE L 107 
AB2 3 ALA C 85  ? GLN C 91  ? ALA L 85  GLN L 91  
AB2 4 LEU C 34  ? GLN C 39  ? LEU L 34  GLN L 39  
AB2 5 ARG C 46  ? TYR C 50  ? ARG L 46  TYR L 50  
AB2 6 SER C 54  ? ARG C 55  ? SER L 54  ARG L 55  
AB3 1 THR C 10  ? LEU C 13  ? THR L 10  LEU L 13  
AB3 2 THR C 103 ? ILE C 107 ? THR L 103 ILE L 107 
AB3 3 ALA C 85  ? GLN C 91  ? ALA L 85  GLN L 91  
AB3 4 THR C 98  ? PHE C 99  ? THR L 98  PHE L 99  
AB4 1 SER C 115 ? PHE C 119 ? SER L 115 PHE L 119 
AB4 2 THR C 130 ? PHE C 140 ? THR L 130 PHE L 140 
AB4 3 TYR C 174 ? SER C 183 ? TYR L 174 SER L 183 
AB4 4 SER C 160 ? VAL C 164 ? SER L 160 VAL L 164 
AB5 1 ALA C 154 ? LEU C 155 ? ALA L 154 LEU L 155 
AB5 2 LYS C 146 ? VAL C 151 ? LYS L 146 VAL L 151 
AB5 3 VAL C 192 ? THR C 198 ? VAL L 192 THR L 198 
AB5 4 VAL C 206 ? ASN C 211 ? VAL L 206 ASN L 211 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 6   ? N THR A 4   O GLU A 24  ? O GLU A 22  
AA1 2 3 N ALA A 19  ? N ALA A 17  O ILE A 81  ? O ILE A 79  
AA1 3 4 O ASN A 78  ? O ASN A 76  N THR A 71  ? N THR A 69  
AA2 1 2 N VAL A 11  ? N VAL A 9   O GLN A 113 ? O GLN A 111 
AA2 2 3 O ILE A 114 ? O ILE A 112 N GLY A 90  ? N GLY A 88  
AA2 3 4 O LEU A 93  ? O LEU A 91  N LEU A 39  ? N LEU A 37  
AA2 4 5 N VAL A 34  ? N VAL A 32  O PHE A 54  ? O PHE A 52  
AA3 1 2 N VAL A 11  ? N VAL A 9   O GLN A 113 ? O GLN A 111 
AA3 2 3 O ILE A 114 ? O ILE A 112 N GLY A 90  ? N GLY A 88  
AA3 3 4 N VAL A 96  ? N VAL A 94  O GLY A 107 ? O GLY A 105 
AA4 1 2 N GLN B 3   ? N GLN H 3   O SER B 25  ? O SER H 25  
AA4 2 3 N LEU B 18  ? N LEU H 18  O MET B 83  ? O MET H 83  
AA4 3 4 O GLN B 82  ? O GLN H 82  N THR B 69  ? N THR H 69  
AA5 1 2 N VAL B 12  ? N VAL H 12  O THR B 115 ? O THR H 115 
AA5 2 3 O THR B 112 ? O THR H 112 N TYR B 94  ? N TYR H 94  
AA5 3 4 O TYR B 95  ? O TYR H 95  N VAL B 37  ? N VAL H 37  
AA5 4 5 N ARG B 38  ? N ARG H 38  O GLU B 46  ? O GLU H 46  
AA5 5 6 N GLY B 50  ? N GLY H 50  O TYR B 59  ? O TYR H 59  
AA6 1 2 N VAL B 12  ? N VAL H 12  O THR B 115 ? O THR H 115 
AA6 2 3 O THR B 112 ? O THR H 112 N TYR B 94  ? N TYR H 94  
AA6 3 4 N ARG B 98  ? N ARG H 98  O TYR B 107 ? O TYR H 107 
AA7 1 2 N PHE B 127 ? N PHE H 127 O LEU B 146 ? O LEU H 146 
AA7 2 3 N VAL B 147 ? N VAL H 147 O LEU B 183 ? O LEU H 183 
AA7 3 4 O VAL B 186 ? O VAL H 186 N HIS B 169 ? N HIS H 169 
AA8 1 2 N PHE B 127 ? N PHE H 127 O LEU B 146 ? O LEU H 146 
AA8 2 3 N VAL B 147 ? N VAL H 147 O LEU B 183 ? O LEU H 183 
AA8 3 4 O SER B 182 ? O SER H 182 N VAL B 174 ? N VAL H 174 
AA9 1 2 N SER B 158 ? N SER H 158 O ASN B 202 ? O ASN H 202 
AA9 2 3 N VAL B 203 ? N VAL H 203 O VAL B 212 ? O VAL H 212 
AB1 1 2 N SER C 7   ? N SER L 7   O SER C 22  ? O SER L 22  
AB1 2 3 N CYS C 23  ? N CYS L 23  O PHE C 72  ? O PHE L 72  
AB1 3 4 O THR C 75  ? O THR L 75  N SER C 64  ? N SER L 64  
AB2 1 2 N LEU C 11  ? N LEU L 11  O LYS C 104 ? O LYS L 104 
AB2 2 3 O VAL C 105 ? O VAL L 105 N ALA C 85  ? N ALA L 85  
AB2 3 4 O VAL C 86  ? O VAL L 86  N GLN C 39  ? N GLN L 39  
AB2 4 5 N TRP C 36  ? N TRP L 36  O LEU C 48  ? O LEU L 48  
AB2 5 6 N TYR C 50  ? N TYR L 50  O SER C 54  ? O SER L 54  
AB3 1 2 N LEU C 11  ? N LEU L 11  O LYS C 104 ? O LYS L 104 
AB3 2 3 O VAL C 105 ? O VAL L 105 N ALA C 85  ? N ALA L 85  
AB3 3 4 N GLN C 91  ? N GLN L 91  O THR C 98  ? O THR L 98  
AB4 1 2 N PHE C 117 ? N PHE L 117 O LEU C 136 ? O LEU L 136 
AB4 2 3 N LEU C 137 ? N LEU L 137 O LEU C 176 ? O LEU L 176 
AB4 3 4 O SER C 177 ? O SER L 177 N SER C 163 ? N SER L 163 
AB5 1 2 O ALA C 154 ? O ALA L 154 N VAL C 151 ? N VAL L 151 
AB5 2 3 N GLN C 148 ? N GLN L 148 O GLU C 196 ? O GLU L 196 
AB5 3 4 N CYS C 195 ? N CYS L 195 O LYS C 208 ? O LYS L 208 
# 
_pdbx_entry_details.entry_id                   9DQ4 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O  H HOH 343 ? ? O H HOH 419 ? ? 2.10 
2 1 OH H TYR 80  ? ? O H HOH 301 ? ? 2.13 
3 1 O  L HOH 416 ? ? O L HOH 432 ? ? 2.15 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     203 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    L 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     323 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   1_554 
_pdbx_validate_symm_contact.dist              2.13 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CB 
_pdbx_validate_rmsd_bond.auth_asym_id_1            H 
_pdbx_validate_rmsd_bond.auth_comp_id_1            VAL 
_pdbx_validate_rmsd_bond.auth_seq_id_1             186 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            CG1 
_pdbx_validate_rmsd_bond.auth_asym_id_2            H 
_pdbx_validate_rmsd_bond.auth_comp_id_2            VAL 
_pdbx_validate_rmsd_bond.auth_seq_id_2             186 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.376 
_pdbx_validate_rmsd_bond.bond_target_value         1.524 
_pdbx_validate_rmsd_bond.bond_deviation            -0.148 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.021 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             H 
_pdbx_validate_rmsd_angle.auth_comp_id_1             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_1              96 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_2             H 
_pdbx_validate_rmsd_angle.auth_comp_id_2             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_2              96 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             SG 
_pdbx_validate_rmsd_angle.auth_asym_id_3             H 
_pdbx_validate_rmsd_angle.auth_comp_id_3             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_3              96 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                122.17 
_pdbx_validate_rmsd_angle.angle_target_value         114.20 
_pdbx_validate_rmsd_angle.angle_deviation            7.97 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 72  ? ? 66.67 -101.97 
2 1 ASP H 149 ? ? 63.39 61.80   
3 1 ALA L 52  ? ? 77.05 -40.15  
4 1 ASP L 152 ? ? 57.14 16.53   
5 1 ASN L 153 ? ? 95.41 -1.54   
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLU -1  ? A GLU 1   
2  1 Y 1 A ALA 0   ? A ALA 2   
3  1 Y 1 A THR 40  ? A THR 42  
4  1 Y 1 A ASN 41  ? A ASN 43  
5  1 Y 1 A ASP 42  ? A ASP 44  
6  1 Y 1 A GLN 43  ? A GLN 45  
7  1 Y 1 A GLU 54  ? A GLU 56  
8  1 Y 1 A LYS 55  ? A LYS 57  
9  1 Y 1 A ASN 56  ? A ASN 58  
10 1 Y 1 A THR 57  ? A THR 59  
11 1 Y 1 A GLY 117 ? A GLY 119 
12 1 Y 1 A HIS 118 ? A HIS 120 
13 1 Y 1 A HIS 119 ? A HIS 121 
14 1 Y 1 A HIS 120 ? A HIS 122 
15 1 Y 1 A HIS 121 ? A HIS 123 
16 1 Y 1 A HIS 122 ? A HIS 124 
17 1 Y 1 A HIS 123 ? A HIS 125 
18 1 Y 1 H SER 132 ? B SER 132 
19 1 Y 1 H SER 133 ? B SER 133 
20 1 Y 1 H LYS 134 ? B LYS 134 
21 1 Y 1 H SER 135 ? B SER 135 
22 1 Y 1 H THR 136 ? B THR 136 
23 1 Y 1 H SER 137 ? B SER 137 
24 1 Y 1 H GLY 138 ? B GLY 138 
25 1 Y 1 H SER 220 ? B SER 220 
26 1 Y 1 H CYS 221 ? B CYS 221 
27 1 Y 1 H GLY 222 ? B GLY 222 
28 1 Y 1 H GLY 223 ? B GLY 223 
29 1 Y 1 H HIS 224 ? B HIS 224 
30 1 Y 1 H HIS 225 ? B HIS 225 
31 1 Y 1 H HIS 226 ? B HIS 226 
32 1 Y 1 H HIS 227 ? B HIS 227 
33 1 Y 1 H HIS 228 ? B HIS 228 
34 1 Y 1 H HIS 229 ? B HIS 229 
35 1 Y 1 L GLU 214 ? C GLU 214 
36 1 Y 1 L CYS 215 ? C CYS 215 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
FUC C1   C N R 112 
FUC C2   C N S 113 
FUC C3   C N R 114 
FUC C4   C N S 115 
FUC C5   C N S 116 
FUC C6   C N N 117 
FUC O1   O N N 118 
FUC O2   O N N 119 
FUC O3   O N N 120 
FUC O4   O N N 121 
FUC O5   O N N 122 
FUC H1   H N N 123 
FUC H2   H N N 124 
FUC H3   H N N 125 
FUC H4   H N N 126 
FUC H5   H N N 127 
FUC H61  H N N 128 
FUC H62  H N N 129 
FUC H63  H N N 130 
FUC HO1  H N N 131 
FUC HO2  H N N 132 
FUC HO3  H N N 133 
FUC HO4  H N N 134 
GLN N    N N N 135 
GLN CA   C N S 136 
GLN C    C N N 137 
GLN O    O N N 138 
GLN CB   C N N 139 
GLN CG   C N N 140 
GLN CD   C N N 141 
GLN OE1  O N N 142 
GLN NE2  N N N 143 
GLN OXT  O N N 144 
GLN H    H N N 145 
GLN H2   H N N 146 
GLN HA   H N N 147 
GLN HB2  H N N 148 
GLN HB3  H N N 149 
GLN HG2  H N N 150 
GLN HG3  H N N 151 
GLN HE21 H N N 152 
GLN HE22 H N N 153 
GLN HXT  H N N 154 
GLU N    N N N 155 
GLU CA   C N S 156 
GLU C    C N N 157 
GLU O    O N N 158 
GLU CB   C N N 159 
GLU CG   C N N 160 
GLU CD   C N N 161 
GLU OE1  O N N 162 
GLU OE2  O N N 163 
GLU OXT  O N N 164 
GLU H    H N N 165 
GLU H2   H N N 166 
GLU HA   H N N 167 
GLU HB2  H N N 168 
GLU HB3  H N N 169 
GLU HG2  H N N 170 
GLU HG3  H N N 171 
GLU HE2  H N N 172 
GLU HXT  H N N 173 
GLY N    N N N 174 
GLY CA   C N N 175 
GLY C    C N N 176 
GLY O    O N N 177 
GLY OXT  O N N 178 
GLY H    H N N 179 
GLY H2   H N N 180 
GLY HA2  H N N 181 
GLY HA3  H N N 182 
GLY HXT  H N N 183 
HIS N    N N N 184 
HIS CA   C N S 185 
HIS C    C N N 186 
HIS O    O N N 187 
HIS CB   C N N 188 
HIS CG   C Y N 189 
HIS ND1  N Y N 190 
HIS CD2  C Y N 191 
HIS CE1  C Y N 192 
HIS NE2  N Y N 193 
HIS OXT  O N N 194 
HIS H    H N N 195 
HIS H2   H N N 196 
HIS HA   H N N 197 
HIS HB2  H N N 198 
HIS HB3  H N N 199 
HIS HD1  H N N 200 
HIS HD2  H N N 201 
HIS HE1  H N N 202 
HIS HE2  H N N 203 
HIS HXT  H N N 204 
HOH O    O N N 205 
HOH H1   H N N 206 
HOH H2   H N N 207 
ILE N    N N N 208 
ILE CA   C N S 209 
ILE C    C N N 210 
ILE O    O N N 211 
ILE CB   C N S 212 
ILE CG1  C N N 213 
ILE CG2  C N N 214 
ILE CD1  C N N 215 
ILE OXT  O N N 216 
ILE H    H N N 217 
ILE H2   H N N 218 
ILE HA   H N N 219 
ILE HB   H N N 220 
ILE HG12 H N N 221 
ILE HG13 H N N 222 
ILE HG21 H N N 223 
ILE HG22 H N N 224 
ILE HG23 H N N 225 
ILE HD11 H N N 226 
ILE HD12 H N N 227 
ILE HD13 H N N 228 
ILE HXT  H N N 229 
LEU N    N N N 230 
LEU CA   C N S 231 
LEU C    C N N 232 
LEU O    O N N 233 
LEU CB   C N N 234 
LEU CG   C N N 235 
LEU CD1  C N N 236 
LEU CD2  C N N 237 
LEU OXT  O N N 238 
LEU H    H N N 239 
LEU H2   H N N 240 
LEU HA   H N N 241 
LEU HB2  H N N 242 
LEU HB3  H N N 243 
LEU HG   H N N 244 
LEU HD11 H N N 245 
LEU HD12 H N N 246 
LEU HD13 H N N 247 
LEU HD21 H N N 248 
LEU HD22 H N N 249 
LEU HD23 H N N 250 
LEU HXT  H N N 251 
LYS N    N N N 252 
LYS CA   C N S 253 
LYS C    C N N 254 
LYS O    O N N 255 
LYS CB   C N N 256 
LYS CG   C N N 257 
LYS CD   C N N 258 
LYS CE   C N N 259 
LYS NZ   N N N 260 
LYS OXT  O N N 261 
LYS H    H N N 262 
LYS H2   H N N 263 
LYS HA   H N N 264 
LYS HB2  H N N 265 
LYS HB3  H N N 266 
LYS HG2  H N N 267 
LYS HG3  H N N 268 
LYS HD2  H N N 269 
LYS HD3  H N N 270 
LYS HE2  H N N 271 
LYS HE3  H N N 272 
LYS HZ1  H N N 273 
LYS HZ2  H N N 274 
LYS HZ3  H N N 275 
LYS HXT  H N N 276 
MET N    N N N 277 
MET CA   C N S 278 
MET C    C N N 279 
MET O    O N N 280 
MET CB   C N N 281 
MET CG   C N N 282 
MET SD   S N N 283 
MET CE   C N N 284 
MET OXT  O N N 285 
MET H    H N N 286 
MET H2   H N N 287 
MET HA   H N N 288 
MET HB2  H N N 289 
MET HB3  H N N 290 
MET HG2  H N N 291 
MET HG3  H N N 292 
MET HE1  H N N 293 
MET HE2  H N N 294 
MET HE3  H N N 295 
MET HXT  H N N 296 
NAG C1   C N R 297 
NAG C2   C N R 298 
NAG C3   C N R 299 
NAG C4   C N S 300 
NAG C5   C N R 301 
NAG C6   C N N 302 
NAG C7   C N N 303 
NAG C8   C N N 304 
NAG N2   N N N 305 
NAG O1   O N N 306 
NAG O3   O N N 307 
NAG O4   O N N 308 
NAG O5   O N N 309 
NAG O6   O N N 310 
NAG O7   O N N 311 
NAG H1   H N N 312 
NAG H2   H N N 313 
NAG H3   H N N 314 
NAG H4   H N N 315 
NAG H5   H N N 316 
NAG H61  H N N 317 
NAG H62  H N N 318 
NAG H81  H N N 319 
NAG H82  H N N 320 
NAG H83  H N N 321 
NAG HN2  H N N 322 
NAG HO1  H N N 323 
NAG HO3  H N N 324 
NAG HO4  H N N 325 
NAG HO6  H N N 326 
PHE N    N N N 327 
PHE CA   C N S 328 
PHE C    C N N 329 
PHE O    O N N 330 
PHE CB   C N N 331 
PHE CG   C Y N 332 
PHE CD1  C Y N 333 
PHE CD2  C Y N 334 
PHE CE1  C Y N 335 
PHE CE2  C Y N 336 
PHE CZ   C Y N 337 
PHE OXT  O N N 338 
PHE H    H N N 339 
PHE H2   H N N 340 
PHE HA   H N N 341 
PHE HB2  H N N 342 
PHE HB3  H N N 343 
PHE HD1  H N N 344 
PHE HD2  H N N 345 
PHE HE1  H N N 346 
PHE HE2  H N N 347 
PHE HZ   H N N 348 
PHE HXT  H N N 349 
PRO N    N N N 350 
PRO CA   C N S 351 
PRO C    C N N 352 
PRO O    O N N 353 
PRO CB   C N N 354 
PRO CG   C N N 355 
PRO CD   C N N 356 
PRO OXT  O N N 357 
PRO H    H N N 358 
PRO HA   H N N 359 
PRO HB2  H N N 360 
PRO HB3  H N N 361 
PRO HG2  H N N 362 
PRO HG3  H N N 363 
PRO HD2  H N N 364 
PRO HD3  H N N 365 
PRO HXT  H N N 366 
SER N    N N N 367 
SER CA   C N S 368 
SER C    C N N 369 
SER O    O N N 370 
SER CB   C N N 371 
SER OG   O N N 372 
SER OXT  O N N 373 
SER H    H N N 374 
SER H2   H N N 375 
SER HA   H N N 376 
SER HB2  H N N 377 
SER HB3  H N N 378 
SER HG   H N N 379 
SER HXT  H N N 380 
THR N    N N N 381 
THR CA   C N S 382 
THR C    C N N 383 
THR O    O N N 384 
THR CB   C N R 385 
THR OG1  O N N 386 
THR CG2  C N N 387 
THR OXT  O N N 388 
THR H    H N N 389 
THR H2   H N N 390 
THR HA   H N N 391 
THR HB   H N N 392 
THR HG1  H N N 393 
THR HG21 H N N 394 
THR HG22 H N N 395 
THR HG23 H N N 396 
THR HXT  H N N 397 
TRP N    N N N 398 
TRP CA   C N S 399 
TRP C    C N N 400 
TRP O    O N N 401 
TRP CB   C N N 402 
TRP CG   C Y N 403 
TRP CD1  C Y N 404 
TRP CD2  C Y N 405 
TRP NE1  N Y N 406 
TRP CE2  C Y N 407 
TRP CE3  C Y N 408 
TRP CZ2  C Y N 409 
TRP CZ3  C Y N 410 
TRP CH2  C Y N 411 
TRP OXT  O N N 412 
TRP H    H N N 413 
TRP H2   H N N 414 
TRP HA   H N N 415 
TRP HB2  H N N 416 
TRP HB3  H N N 417 
TRP HD1  H N N 418 
TRP HE1  H N N 419 
TRP HE3  H N N 420 
TRP HZ2  H N N 421 
TRP HZ3  H N N 422 
TRP HH2  H N N 423 
TRP HXT  H N N 424 
TYR N    N N N 425 
TYR CA   C N S 426 
TYR C    C N N 427 
TYR O    O N N 428 
TYR CB   C N N 429 
TYR CG   C Y N 430 
TYR CD1  C Y N 431 
TYR CD2  C Y N 432 
TYR CE1  C Y N 433 
TYR CE2  C Y N 434 
TYR CZ   C Y N 435 
TYR OH   O N N 436 
TYR OXT  O N N 437 
TYR H    H N N 438 
TYR H2   H N N 439 
TYR HA   H N N 440 
TYR HB2  H N N 441 
TYR HB3  H N N 442 
TYR HD1  H N N 443 
TYR HD2  H N N 444 
TYR HE1  H N N 445 
TYR HE2  H N N 446 
TYR HH   H N N 447 
TYR HXT  H N N 448 
VAL N    N N N 449 
VAL CA   C N S 450 
VAL C    C N N 451 
VAL O    O N N 452 
VAL CB   C N N 453 
VAL CG1  C N N 454 
VAL CG2  C N N 455 
VAL OXT  O N N 456 
VAL H    H N N 457 
VAL H2   H N N 458 
VAL HA   H N N 459 
VAL HB   H N N 460 
VAL HG11 H N N 461 
VAL HG12 H N N 462 
VAL HG13 H N N 463 
VAL HG21 H N N 464 
VAL HG22 H N N 465 
VAL HG23 H N N 466 
VAL HXT  H N N 467 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
FUC C1  C2   sing N N 107 
FUC C1  O1   sing N N 108 
FUC C1  O5   sing N N 109 
FUC C1  H1   sing N N 110 
FUC C2  C3   sing N N 111 
FUC C2  O2   sing N N 112 
FUC C2  H2   sing N N 113 
FUC C3  C4   sing N N 114 
FUC C3  O3   sing N N 115 
FUC C3  H3   sing N N 116 
FUC C4  C5   sing N N 117 
FUC C4  O4   sing N N 118 
FUC C4  H4   sing N N 119 
FUC C5  C6   sing N N 120 
FUC C5  O5   sing N N 121 
FUC C5  H5   sing N N 122 
FUC C6  H61  sing N N 123 
FUC C6  H62  sing N N 124 
FUC C6  H63  sing N N 125 
FUC O1  HO1  sing N N 126 
FUC O2  HO2  sing N N 127 
FUC O3  HO3  sing N N 128 
FUC O4  HO4  sing N N 129 
GLN N   CA   sing N N 130 
GLN N   H    sing N N 131 
GLN N   H2   sing N N 132 
GLN CA  C    sing N N 133 
GLN CA  CB   sing N N 134 
GLN CA  HA   sing N N 135 
GLN C   O    doub N N 136 
GLN C   OXT  sing N N 137 
GLN CB  CG   sing N N 138 
GLN CB  HB2  sing N N 139 
GLN CB  HB3  sing N N 140 
GLN CG  CD   sing N N 141 
GLN CG  HG2  sing N N 142 
GLN CG  HG3  sing N N 143 
GLN CD  OE1  doub N N 144 
GLN CD  NE2  sing N N 145 
GLN NE2 HE21 sing N N 146 
GLN NE2 HE22 sing N N 147 
GLN OXT HXT  sing N N 148 
GLU N   CA   sing N N 149 
GLU N   H    sing N N 150 
GLU N   H2   sing N N 151 
GLU CA  C    sing N N 152 
GLU CA  CB   sing N N 153 
GLU CA  HA   sing N N 154 
GLU C   O    doub N N 155 
GLU C   OXT  sing N N 156 
GLU CB  CG   sing N N 157 
GLU CB  HB2  sing N N 158 
GLU CB  HB3  sing N N 159 
GLU CG  CD   sing N N 160 
GLU CG  HG2  sing N N 161 
GLU CG  HG3  sing N N 162 
GLU CD  OE1  doub N N 163 
GLU CD  OE2  sing N N 164 
GLU OE2 HE2  sing N N 165 
GLU OXT HXT  sing N N 166 
GLY N   CA   sing N N 167 
GLY N   H    sing N N 168 
GLY N   H2   sing N N 169 
GLY CA  C    sing N N 170 
GLY CA  HA2  sing N N 171 
GLY CA  HA3  sing N N 172 
GLY C   O    doub N N 173 
GLY C   OXT  sing N N 174 
GLY OXT HXT  sing N N 175 
HIS N   CA   sing N N 176 
HIS N   H    sing N N 177 
HIS N   H2   sing N N 178 
HIS CA  C    sing N N 179 
HIS CA  CB   sing N N 180 
HIS CA  HA   sing N N 181 
HIS C   O    doub N N 182 
HIS C   OXT  sing N N 183 
HIS CB  CG   sing N N 184 
HIS CB  HB2  sing N N 185 
HIS CB  HB3  sing N N 186 
HIS CG  ND1  sing Y N 187 
HIS CG  CD2  doub Y N 188 
HIS ND1 CE1  doub Y N 189 
HIS ND1 HD1  sing N N 190 
HIS CD2 NE2  sing Y N 191 
HIS CD2 HD2  sing N N 192 
HIS CE1 NE2  sing Y N 193 
HIS CE1 HE1  sing N N 194 
HIS NE2 HE2  sing N N 195 
HIS OXT HXT  sing N N 196 
HOH O   H1   sing N N 197 
HOH O   H2   sing N N 198 
ILE N   CA   sing N N 199 
ILE N   H    sing N N 200 
ILE N   H2   sing N N 201 
ILE CA  C    sing N N 202 
ILE CA  CB   sing N N 203 
ILE CA  HA   sing N N 204 
ILE C   O    doub N N 205 
ILE C   OXT  sing N N 206 
ILE CB  CG1  sing N N 207 
ILE CB  CG2  sing N N 208 
ILE CB  HB   sing N N 209 
ILE CG1 CD1  sing N N 210 
ILE CG1 HG12 sing N N 211 
ILE CG1 HG13 sing N N 212 
ILE CG2 HG21 sing N N 213 
ILE CG2 HG22 sing N N 214 
ILE CG2 HG23 sing N N 215 
ILE CD1 HD11 sing N N 216 
ILE CD1 HD12 sing N N 217 
ILE CD1 HD13 sing N N 218 
ILE OXT HXT  sing N N 219 
LEU N   CA   sing N N 220 
LEU N   H    sing N N 221 
LEU N   H2   sing N N 222 
LEU CA  C    sing N N 223 
LEU CA  CB   sing N N 224 
LEU CA  HA   sing N N 225 
LEU C   O    doub N N 226 
LEU C   OXT  sing N N 227 
LEU CB  CG   sing N N 228 
LEU CB  HB2  sing N N 229 
LEU CB  HB3  sing N N 230 
LEU CG  CD1  sing N N 231 
LEU CG  CD2  sing N N 232 
LEU CG  HG   sing N N 233 
LEU CD1 HD11 sing N N 234 
LEU CD1 HD12 sing N N 235 
LEU CD1 HD13 sing N N 236 
LEU CD2 HD21 sing N N 237 
LEU CD2 HD22 sing N N 238 
LEU CD2 HD23 sing N N 239 
LEU OXT HXT  sing N N 240 
LYS N   CA   sing N N 241 
LYS N   H    sing N N 242 
LYS N   H2   sing N N 243 
LYS CA  C    sing N N 244 
LYS CA  CB   sing N N 245 
LYS CA  HA   sing N N 246 
LYS C   O    doub N N 247 
LYS C   OXT  sing N N 248 
LYS CB  CG   sing N N 249 
LYS CB  HB2  sing N N 250 
LYS CB  HB3  sing N N 251 
LYS CG  CD   sing N N 252 
LYS CG  HG2  sing N N 253 
LYS CG  HG3  sing N N 254 
LYS CD  CE   sing N N 255 
LYS CD  HD2  sing N N 256 
LYS CD  HD3  sing N N 257 
LYS CE  NZ   sing N N 258 
LYS CE  HE2  sing N N 259 
LYS CE  HE3  sing N N 260 
LYS NZ  HZ1  sing N N 261 
LYS NZ  HZ2  sing N N 262 
LYS NZ  HZ3  sing N N 263 
LYS OXT HXT  sing N N 264 
MET N   CA   sing N N 265 
MET N   H    sing N N 266 
MET N   H2   sing N N 267 
MET CA  C    sing N N 268 
MET CA  CB   sing N N 269 
MET CA  HA   sing N N 270 
MET C   O    doub N N 271 
MET C   OXT  sing N N 272 
MET CB  CG   sing N N 273 
MET CB  HB2  sing N N 274 
MET CB  HB3  sing N N 275 
MET CG  SD   sing N N 276 
MET CG  HG2  sing N N 277 
MET CG  HG3  sing N N 278 
MET SD  CE   sing N N 279 
MET CE  HE1  sing N N 280 
MET CE  HE2  sing N N 281 
MET CE  HE3  sing N N 282 
MET OXT HXT  sing N N 283 
NAG C1  C2   sing N N 284 
NAG C1  O1   sing N N 285 
NAG C1  O5   sing N N 286 
NAG C1  H1   sing N N 287 
NAG C2  C3   sing N N 288 
NAG C2  N2   sing N N 289 
NAG C2  H2   sing N N 290 
NAG C3  C4   sing N N 291 
NAG C3  O3   sing N N 292 
NAG C3  H3   sing N N 293 
NAG C4  C5   sing N N 294 
NAG C4  O4   sing N N 295 
NAG C4  H4   sing N N 296 
NAG C5  C6   sing N N 297 
NAG C5  O5   sing N N 298 
NAG C5  H5   sing N N 299 
NAG C6  O6   sing N N 300 
NAG C6  H61  sing N N 301 
NAG C6  H62  sing N N 302 
NAG C7  C8   sing N N 303 
NAG C7  N2   sing N N 304 
NAG C7  O7   doub N N 305 
NAG C8  H81  sing N N 306 
NAG C8  H82  sing N N 307 
NAG C8  H83  sing N N 308 
NAG N2  HN2  sing N N 309 
NAG O1  HO1  sing N N 310 
NAG O3  HO3  sing N N 311 
NAG O4  HO4  sing N N 312 
NAG O6  HO6  sing N N 313 
PHE N   CA   sing N N 314 
PHE N   H    sing N N 315 
PHE N   H2   sing N N 316 
PHE CA  C    sing N N 317 
PHE CA  CB   sing N N 318 
PHE CA  HA   sing N N 319 
PHE C   O    doub N N 320 
PHE C   OXT  sing N N 321 
PHE CB  CG   sing N N 322 
PHE CB  HB2  sing N N 323 
PHE CB  HB3  sing N N 324 
PHE CG  CD1  doub Y N 325 
PHE CG  CD2  sing Y N 326 
PHE CD1 CE1  sing Y N 327 
PHE CD1 HD1  sing N N 328 
PHE CD2 CE2  doub Y N 329 
PHE CD2 HD2  sing N N 330 
PHE CE1 CZ   doub Y N 331 
PHE CE1 HE1  sing N N 332 
PHE CE2 CZ   sing Y N 333 
PHE CE2 HE2  sing N N 334 
PHE CZ  HZ   sing N N 335 
PHE OXT HXT  sing N N 336 
PRO N   CA   sing N N 337 
PRO N   CD   sing N N 338 
PRO N   H    sing N N 339 
PRO CA  C    sing N N 340 
PRO CA  CB   sing N N 341 
PRO CA  HA   sing N N 342 
PRO C   O    doub N N 343 
PRO C   OXT  sing N N 344 
PRO CB  CG   sing N N 345 
PRO CB  HB2  sing N N 346 
PRO CB  HB3  sing N N 347 
PRO CG  CD   sing N N 348 
PRO CG  HG2  sing N N 349 
PRO CG  HG3  sing N N 350 
PRO CD  HD2  sing N N 351 
PRO CD  HD3  sing N N 352 
PRO OXT HXT  sing N N 353 
SER N   CA   sing N N 354 
SER N   H    sing N N 355 
SER N   H2   sing N N 356 
SER CA  C    sing N N 357 
SER CA  CB   sing N N 358 
SER CA  HA   sing N N 359 
SER C   O    doub N N 360 
SER C   OXT  sing N N 361 
SER CB  OG   sing N N 362 
SER CB  HB2  sing N N 363 
SER CB  HB3  sing N N 364 
SER OG  HG   sing N N 365 
SER OXT HXT  sing N N 366 
THR N   CA   sing N N 367 
THR N   H    sing N N 368 
THR N   H2   sing N N 369 
THR CA  C    sing N N 370 
THR CA  CB   sing N N 371 
THR CA  HA   sing N N 372 
THR C   O    doub N N 373 
THR C   OXT  sing N N 374 
THR CB  OG1  sing N N 375 
THR CB  CG2  sing N N 376 
THR CB  HB   sing N N 377 
THR OG1 HG1  sing N N 378 
THR CG2 HG21 sing N N 379 
THR CG2 HG22 sing N N 380 
THR CG2 HG23 sing N N 381 
THR OXT HXT  sing N N 382 
TRP N   CA   sing N N 383 
TRP N   H    sing N N 384 
TRP N   H2   sing N N 385 
TRP CA  C    sing N N 386 
TRP CA  CB   sing N N 387 
TRP CA  HA   sing N N 388 
TRP C   O    doub N N 389 
TRP C   OXT  sing N N 390 
TRP CB  CG   sing N N 391 
TRP CB  HB2  sing N N 392 
TRP CB  HB3  sing N N 393 
TRP CG  CD1  doub Y N 394 
TRP CG  CD2  sing Y N 395 
TRP CD1 NE1  sing Y N 396 
TRP CD1 HD1  sing N N 397 
TRP CD2 CE2  doub Y N 398 
TRP CD2 CE3  sing Y N 399 
TRP NE1 CE2  sing Y N 400 
TRP NE1 HE1  sing N N 401 
TRP CE2 CZ2  sing Y N 402 
TRP CE3 CZ3  doub Y N 403 
TRP CE3 HE3  sing N N 404 
TRP CZ2 CH2  doub Y N 405 
TRP CZ2 HZ2  sing N N 406 
TRP CZ3 CH2  sing Y N 407 
TRP CZ3 HZ3  sing N N 408 
TRP CH2 HH2  sing N N 409 
TRP OXT HXT  sing N N 410 
TYR N   CA   sing N N 411 
TYR N   H    sing N N 412 
TYR N   H2   sing N N 413 
TYR CA  C    sing N N 414 
TYR CA  CB   sing N N 415 
TYR CA  HA   sing N N 416 
TYR C   O    doub N N 417 
TYR C   OXT  sing N N 418 
TYR CB  CG   sing N N 419 
TYR CB  HB2  sing N N 420 
TYR CB  HB3  sing N N 421 
TYR CG  CD1  doub Y N 422 
TYR CG  CD2  sing Y N 423 
TYR CD1 CE1  sing Y N 424 
TYR CD1 HD1  sing N N 425 
TYR CD2 CE2  doub Y N 426 
TYR CD2 HD2  sing N N 427 
TYR CE1 CZ   doub Y N 428 
TYR CE1 HE1  sing N N 429 
TYR CE2 CZ   sing Y N 430 
TYR CE2 HE2  sing N N 431 
TYR CZ  OH   sing N N 432 
TYR OH  HH   sing N N 433 
TYR OXT HXT  sing N N 434 
VAL N   CA   sing N N 435 
VAL N   H    sing N N 436 
VAL N   H2   sing N N 437 
VAL CA  C    sing N N 438 
VAL CA  CB   sing N N 439 
VAL CA  HA   sing N N 440 
VAL C   O    doub N N 441 
VAL C   OXT  sing N N 442 
VAL CB  CG1  sing N N 443 
VAL CB  CG2  sing N N 444 
VAL CB  HB   sing N N 445 
VAL CG1 HG11 sing N N 446 
VAL CG1 HG12 sing N N 447 
VAL CG1 HG13 sing N N 448 
VAL CG2 HG21 sing N N 449 
VAL CG2 HG22 sing N N 450 
VAL CG2 HG23 sing N N 451 
VAL OXT HXT  sing N N 452 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
4 NAG 1 n 
4 NAG 2 n 
4 BMA 3 n 
4 FUC 4 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6RP8 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9DQ4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012149 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006545 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.020828 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . ILE A 1 3   ? 15.181  10.841 -11.685 1.00 18.12 ? 1   ILE A N    1 
ATOM   2    C CA   . ILE A 1 3   ? 16.330  10.402 -12.525 1.00 15.93 ? 1   ILE A CA   1 
ATOM   3    C C    . ILE A 1 3   ? 17.311  9.523  -11.782 1.00 16.83 ? 1   ILE A C    1 
ATOM   4    O O    . ILE A 1 3   ? 17.582  9.720  -10.623 1.00 15.92 ? 1   ILE A O    1 
ATOM   5    C CB   . ILE A 1 3   ? 17.016  11.645 -13.196 1.00 13.86 ? 1   ILE A CB   1 
ATOM   6    C CG1  . ILE A 1 3   ? 17.644  12.611 -12.198 1.00 13.11 ? 1   ILE A CG1  1 
ATOM   7    C CG2  . ILE A 1 3   ? 16.054  12.354 -14.109 1.00 17.43 ? 1   ILE A CG2  1 
ATOM   8    C CD1  . ILE A 1 3   ? 18.591  13.607 -12.843 1.00 15.21 ? 1   ILE A CD1  1 
ATOM   9    H H    . ILE A 1 3   ? 14.501  11.072 -12.211 1.00 21.80 ? 1   ILE A H    1 
ATOM   10   H HA   . ILE A 1 3   ? 15.984  9.830  -13.229 1.00 19.17 ? 1   ILE A HA   1 
ATOM   11   H HB   . ILE A 1 3   ? 17.753  11.295 -13.720 1.00 16.69 ? 1   ILE A HB   1 
ATOM   12   H HG12 . ILE A 1 3   ? 16.939  13.112 -11.759 1.00 15.79 ? 1   ILE A HG12 1 
ATOM   13   H HG13 . ILE A 1 3   ? 18.147  12.103 -11.543 1.00 15.79 ? 1   ILE A HG13 1 
ATOM   14   H HG21 . ILE A 1 3   ? 16.511  13.097 -14.534 1.00 20.98 ? 1   ILE A HG21 1 
ATOM   15   H HG22 . ILE A 1 3   ? 15.740  11.730 -14.782 1.00 20.98 ? 1   ILE A HG22 1 
ATOM   16   H HG23 . ILE A 1 3   ? 15.305  12.682 -13.587 1.00 20.98 ? 1   ILE A HG23 1 
ATOM   17   H HD11 . ILE A 1 3   ? 18.975  14.170 -12.153 1.00 18.31 ? 1   ILE A HD11 1 
ATOM   18   H HD12 . ILE A 1 3   ? 19.293  13.123 -13.304 1.00 18.31 ? 1   ILE A HD12 1 
ATOM   19   H HD13 . ILE A 1 3   ? 18.094  14.151 -13.475 1.00 18.31 ? 1   ILE A HD13 1 
ATOM   20   N N    . GLN A 1 4   ? 17.780  8.498  -12.474 1.00 14.69 ? 2   GLN A N    1 
ATOM   21   C CA   . GLN A 1 4   ? 18.777  7.569  -11.969 1.00 16.94 ? 2   GLN A CA   1 
ATOM   22   C C    . GLN A 1 4   ? 20.121  7.979  -12.567 1.00 16.66 ? 2   GLN A C    1 
ATOM   23   O O    . GLN A 1 4   ? 20.282  8.004  -13.795 1.00 14.57 ? 2   GLN A O    1 
ATOM   24   C CB   . GLN A 1 4   ? 18.421  6.135  -12.358 1.00 20.53 ? 2   GLN A CB   1 
ATOM   25   C CG   . GLN A 1 4   ? 19.554  5.139  -12.233 1.00 24.19 ? 2   GLN A CG   1 
ATOM   26   C CD   . GLN A 1 4   ? 19.064  3.701  -12.128 1.00 31.85 ? 2   GLN A CD   1 
ATOM   27   O OE1  . GLN A 1 4   ? 19.260  2.921  -13.041 1.00 36.31 ? 2   GLN A OE1  1 
ATOM   28   N NE2  . GLN A 1 4   ? 18.420  3.354  -11.018 1.00 34.47 ? 2   GLN A NE2  1 
ATOM   29   H H    . GLN A 1 4   ? 17.525  8.312  -13.274 1.00 17.69 ? 2   GLN A H    1 
ATOM   30   H HA   . GLN A 1 4   ? 18.829  7.608  -11.001 1.00 20.39 ? 2   GLN A HA   1 
ATOM   31   H HB2  . GLN A 1 4   ? 17.701  5.831  -11.784 1.00 24.69 ? 2   GLN A HB2  1 
ATOM   32   H HB3  . GLN A 1 4   ? 18.131  6.132  -13.284 1.00 24.69 ? 2   GLN A HB3  1 
ATOM   33   H HG2  . GLN A 1 4   ? 20.122  5.207  -13.016 1.00 29.09 ? 2   GLN A HG2  1 
ATOM   34   H HG3  . GLN A 1 4   ? 20.065  5.341  -11.434 1.00 29.09 ? 2   GLN A HG3  1 
ATOM   35   H HE21 . GLN A 1 4   ? 18.295  3.932  -10.394 1.00 41.43 ? 2   GLN A HE21 1 
ATOM   36   H HE22 . GLN A 1 4   ? 18.129  2.550  -10.923 1.00 41.43 ? 2   GLN A HE22 1 
ATOM   37   N N    . VAL A 1 5   ? 21.080  8.288  -11.706 1.00 14.52 ? 3   VAL A N    1 
ATOM   38   C CA   . VAL A 1 5   ? 22.441  8.618  -12.113 1.00 12.41 ? 3   VAL A CA   1 
ATOM   39   C C    . VAL A 1 5   ? 23.317  7.378  -11.952 1.00 15.39 ? 3   VAL A C    1 
ATOM   40   O O    . VAL A 1 5   ? 23.344  6.748  -10.876 1.00 15.44 ? 3   VAL A O    1 
ATOM   41   C CB   . VAL A 1 5   ? 22.989  9.812  -11.314 1.00 14.98 ? 3   VAL A CB   1 
ATOM   42   C CG1  . VAL A 1 5   ? 24.470  10.039 -11.661 1.00 20.34 ? 3   VAL A CG1  1 
ATOM   43   C CG2  . VAL A 1 5   ? 22.154  11.057 -11.626 1.00 15.37 ? 3   VAL A CG2  1 
ATOM   44   H H    . VAL A 1 5   ? 20.965  8.315  -10.854 1.00 17.48 ? 3   VAL A H    1 
ATOM   45   H HA   . VAL A 1 5   ? 22.447  8.862  -13.052 1.00 14.95 ? 3   VAL A HA   1 
ATOM   46   H HB   . VAL A 1 5   ? 22.929  9.634  -10.362 1.00 18.04 ? 3   VAL A HB   1 
ATOM   47   H HG11 . VAL A 1 5   ? 24.750  10.897 -11.305 1.00 24.47 ? 3   VAL A HG11 1 
ATOM   48   H HG12 . VAL A 1 5   ? 24.999  9.329  -11.267 1.00 24.47 ? 3   VAL A HG12 1 
ATOM   49   H HG13 . VAL A 1 5   ? 24.573  10.032 -12.626 1.00 24.47 ? 3   VAL A HG13 1 
ATOM   50   H HG21 . VAL A 1 5   ? 22.529  11.815 -11.152 1.00 18.51 ? 3   VAL A HG21 1 
ATOM   51   H HG22 . VAL A 1 5   ? 22.175  11.220 -12.582 1.00 18.51 ? 3   VAL A HG22 1 
ATOM   52   H HG23 . VAL A 1 5   ? 21.241  10.905 -11.336 1.00 18.51 ? 3   VAL A HG23 1 
ATOM   53   N N    . THR A 1 6   ? 24.025  7.015  -13.018 1.00 18.20 ? 4   THR A N    1 
ATOM   54   C CA   . THR A 1 6   ? 24.949  5.887  -12.973 1.00 17.73 ? 4   THR A CA   1 
ATOM   55   C C    . THR A 1 6   ? 26.382  6.355  -13.188 1.00 19.32 ? 4   THR A C    1 
ATOM   56   O O    . THR A 1 6   ? 26.661  7.153  -14.094 1.00 18.17 ? 4   THR A O    1 
ATOM   57   C CB   . THR A 1 6   ? 24.605  4.845  -14.028 1.00 21.94 ? 4   THR A CB   1 
ATOM   58   O OG1  . THR A 1 6   ? 24.676  5.436  -15.331 1.00 28.96 ? 4   THR A OG1  1 
ATOM   59   C CG2  . THR A 1 6   ? 23.224  4.338  -13.837 1.00 20.50 ? 4   THR A CG2  1 
ATOM   60   H H    . THR A 1 6   ? 23.987  7.409  -13.781 1.00 21.90 ? 4   THR A H    1 
ATOM   61   H HA   . THR A 1 6   ? 24.887  5.488  -12.091 1.00 21.34 ? 4   THR A HA   1 
ATOM   62   H HB   . THR A 1 6   ? 25.231  4.108  -13.954 1.00 26.39 ? 4   THR A HB   1 
ATOM   63   H HG1  . THR A 1 6   ? 24.447  4.876  -15.914 1.00 34.81 ? 4   THR A HG1  1 
ATOM   64   H HG21 . THR A 1 6   ? 23.031  3.647  -14.489 1.00 24.67 ? 4   THR A HG21 1 
ATOM   65   H HG22 . THR A 1 6   ? 23.128  3.965  -12.946 1.00 24.67 ? 4   THR A HG22 1 
ATOM   66   H HG23 . THR A 1 6   ? 22.587  5.061  -13.946 1.00 24.67 ? 4   THR A HG23 1 
ATOM   67   N N    . GLN A 1 7   ? 27.282  5.829  -12.366 1.00 15.92 ? 5   GLN A N    1 
ATOM   68   C CA   . GLN A 1 7   ? 28.707  6.082  -12.456 1.00 14.85 ? 5   GLN A CA   1 
ATOM   69   C C    . GLN A 1 7   ? 29.412  4.804  -11.997 1.00 17.62 ? 5   GLN A C    1 
ATOM   70   O O    . GLN A 1 7   ? 28.834  4.029  -11.231 1.00 18.48 ? 5   GLN A O    1 
ATOM   71   C CB   . GLN A 1 7   ? 29.101  7.301  -11.594 1.00 18.24 ? 5   GLN A CB   1 
ATOM   72   C CG   . GLN A 1 7   ? 28.969  7.109  -10.101 1.00 14.26 ? 5   GLN A CG   1 
ATOM   73   C CD   . GLN A 1 7   ? 29.230  8.375  -9.282  1.00 18.22 ? 5   GLN A CD   1 
ATOM   74   O OE1  . GLN A 1 7   ? 28.346  8.928  -8.638  1.00 17.17 ? 5   GLN A OE1  1 
ATOM   75   N NE2  . GLN A 1 7   ? 30.458  8.878  -9.391  1.00 15.55 ? 5   GLN A NE2  1 
ATOM   76   H H    . GLN A 1 7   ? 27.080  5.299  -11.720 1.00 19.17 ? 5   GLN A H    1 
ATOM   77   H HA   . GLN A 1 7   ? 28.986  6.272  -13.365 1.00 17.88 ? 5   GLN A HA   1 
ATOM   78   H HB2  . GLN A 1 7   ? 30.029  7.517  -11.777 1.00 21.95 ? 5   GLN A HB2  1 
ATOM   79   H HB3  . GLN A 1 7   ? 28.532  8.046  -11.841 1.00 21.95 ? 5   GLN A HB3  1 
ATOM   80   H HG2  . GLN A 1 7   ? 28.066  6.813  -9.904  1.00 17.17 ? 5   GLN A HG2  1 
ATOM   81   H HG3  . GLN A 1 7   ? 29.608  6.438  -9.816  1.00 17.17 ? 5   GLN A HG3  1 
ATOM   82   H HE21 . GLN A 1 7   ? 31.038  8.491  -9.895  1.00 18.72 ? 5   GLN A HE21 1 
ATOM   83   H HE22 . GLN A 1 7   ? 30.672  9.589  -8.957  1.00 18.72 ? 5   GLN A HE22 1 
ATOM   84   N N    . PRO A 1 8   ? 30.630  4.539  -12.467 1.00 20.20 ? 6   PRO A N    1 
ATOM   85   C CA   . PRO A 1 8   ? 31.286  3.263  -12.137 1.00 20.34 ? 6   PRO A CA   1 
ATOM   86   C C    . PRO A 1 8   ? 31.641  3.171  -10.659 1.00 20.85 ? 6   PRO A C    1 
ATOM   87   O O    . PRO A 1 8   ? 32.000  4.161  -10.015 1.00 21.53 ? 6   PRO A O    1 
ATOM   88   C CB   . PRO A 1 8   ? 32.556  3.277  -13.011 1.00 20.37 ? 6   PRO A CB   1 
ATOM   89   C CG   . PRO A 1 8   ? 32.801  4.695  -13.312 1.00 22.30 ? 6   PRO A CG   1 
ATOM   90   C CD   . PRO A 1 8   ? 31.407  5.290  -13.461 1.00 18.74 ? 6   PRO A CD   1 
ATOM   91   H HA   . PRO A 1 8   ? 30.721  2.515  -12.384 1.00 24.47 ? 6   PRO A HA   1 
ATOM   92   H HB2  . PRO A 1 8   ? 33.299  2.894  -12.519 1.00 24.50 ? 6   PRO A HB2  1 
ATOM   93   H HB3  . PRO A 1 8   ? 32.401  2.772  -13.825 1.00 24.50 ? 6   PRO A HB3  1 
ATOM   94   H HG2  . PRO A 1 8   ? 33.283  5.113  -12.582 1.00 26.82 ? 6   PRO A HG2  1 
ATOM   95   H HG3  . PRO A 1 8   ? 33.307  4.779  -14.135 1.00 26.82 ? 6   PRO A HG3  1 
ATOM   96   H HD2  . PRO A 1 8   ? 31.410  6.238  -13.257 1.00 22.55 ? 6   PRO A HD2  1 
ATOM   97   H HD3  . PRO A 1 8   ? 31.061  5.145  -14.356 1.00 22.55 ? 6   PRO A HD3  1 
ATOM   98   N N    . SER A 1 9   ? 31.565  1.947  -10.133 1.00 20.61 ? 7   SER A N    1 
ATOM   99   C CA   . SER A 1 9   ? 31.874  1.734  -8.726  1.00 25.00 ? 7   SER A CA   1 
ATOM   100  C C    . SER A 1 9   ? 33.300  2.140  -8.405  1.00 19.15 ? 7   SER A C    1 
ATOM   101  O O    . SER A 1 9   ? 33.563  2.681  -7.327  1.00 20.32 ? 7   SER A O    1 
ATOM   102  C CB   . SER A 1 9   ? 31.655  0.271  -8.337  1.00 25.52 ? 7   SER A CB   1 
ATOM   103  O OG   . SER A 1 9   ? 30.348  -0.168 -8.639  1.00 39.85 ? 7   SER A OG   1 
ATOM   104  H H    . SER A 1 9   ? 31.342  1.237  -10.565 1.00 24.79 ? 7   SER A H    1 
ATOM   105  H HA   . SER A 1 9   ? 31.267  2.282  -8.203  1.00 30.06 ? 7   SER A HA   1 
ATOM   106  H HB2  . SER A 1 9   ? 32.289  -0.278 -8.824  1.00 30.68 ? 7   SER A HB2  1 
ATOM   107  H HB3  . SER A 1 9   ? 31.801  0.178  -7.382  1.00 30.68 ? 7   SER A HB3  1 
ATOM   108  H HG   . SER A 1 9   ? 30.281  -0.992 -8.493  1.00 47.88 ? 7   SER A HG   1 
ATOM   109  N N    . VAL A 1 10  ? 34.237  1.862  -9.302  1.00 23.33 ? 8   VAL A N    1 
ATOM   110  C CA   . VAL A 1 10  ? 35.647  2.088  -9.003  1.00 17.38 ? 8   VAL A CA   1 
ATOM   111  C C    . VAL A 1 10  ? 36.374  2.446  -10.292 1.00 20.12 ? 8   VAL A C    1 
ATOM   112  O O    . VAL A 1 10  ? 36.092  1.875  -11.356 1.00 23.23 ? 8   VAL A O    1 
ATOM   113  C CB   . VAL A 1 10  ? 36.274  0.840  -8.341  1.00 23.79 ? 8   VAL A CB   1 
ATOM   114  C CG1  . VAL A 1 10  ? 35.873  -0.369 -9.133  1.00 28.17 ? 8   VAL A CG1  1 
ATOM   115  C CG2  . VAL A 1 10  ? 37.793  0.997  -8.231  1.00 25.39 ? 8   VAL A CG2  1 
ATOM   116  H H    . VAL A 1 10  ? 34.084  1.543  -10.086 1.00 28.06 ? 8   VAL A H    1 
ATOM   117  H HA   . VAL A 1 10  ? 35.727  2.842  -8.398  1.00 20.92 ? 8   VAL A HA   1 
ATOM   118  H HB   . VAL A 1 10  ? 35.950  0.728  -7.433  1.00 28.61 ? 8   VAL A HB   1 
ATOM   119  H HG11 . VAL A 1 10  ? 36.310  -1.150 -8.759  1.00 33.87 ? 8   VAL A HG11 1 
ATOM   120  H HG12 . VAL A 1 10  ? 34.910  -0.473 -9.084  1.00 33.87 ? 8   VAL A HG12 1 
ATOM   121  H HG13 . VAL A 1 10  ? 36.147  -0.246 -10.055 1.00 33.87 ? 8   VAL A HG13 1 
ATOM   122  H HG21 . VAL A 1 10  ? 38.134  0.340  -7.604  1.00 30.52 ? 8   VAL A HG21 1 
ATOM   123  H HG22 . VAL A 1 10  ? 38.188  0.856  -9.105  1.00 30.52 ? 8   VAL A HG22 1 
ATOM   124  H HG23 . VAL A 1 10  ? 37.996  1.892  -7.916  1.00 30.52 ? 8   VAL A HG23 1 
ATOM   125  N N    . VAL A 1 11  ? 37.298  3.407  -10.202 1.00 21.36 ? 9   VAL A N    1 
ATOM   126  C CA   . VAL A 1 11  ? 38.231  3.708  -11.281 1.00 22.35 ? 9   VAL A CA   1 
ATOM   127  C C    . VAL A 1 11  ? 39.624  3.868  -10.689 1.00 24.45 ? 9   VAL A C    1 
ATOM   128  O O    . VAL A 1 11  ? 39.793  4.246  -9.522  1.00 21.89 ? 9   VAL A O    1 
ATOM   129  C CB   . VAL A 1 11  ? 37.849  4.984  -12.044 1.00 24.33 ? 9   VAL A CB   1 
ATOM   130  C CG1  . VAL A 1 11  ? 36.527  4.773  -12.791 1.00 28.26 ? 9   VAL A CG1  1 
ATOM   131  C CG2  . VAL A 1 11  ? 37.777  6.132  -11.140 1.00 29.91 ? 9   VAL A CG2  1 
ATOM   132  H H    . VAL A 1 11  ? 37.403  3.907  -9.510  1.00 25.69 ? 9   VAL A H    1 
ATOM   133  H HA   . VAL A 1 11  ? 38.232  2.964  -11.903 1.00 26.88 ? 9   VAL A HA   1 
ATOM   134  H HB   . VAL A 1 11  ? 38.537  5.182  -12.699 1.00 29.25 ? 9   VAL A HB   1 
ATOM   135  H HG11 . VAL A 1 11  ? 36.449  5.441  -13.490 1.00 33.97 ? 9   VAL A HG11 1 
ATOM   136  H HG12 . VAL A 1 11  ? 36.523  3.885  -13.180 1.00 33.97 ? 9   VAL A HG12 1 
ATOM   137  H HG13 . VAL A 1 11  ? 35.792  4.864  -12.164 1.00 33.97 ? 9   VAL A HG13 1 
ATOM   138  H HG21 . VAL A 1 11  ? 37.362  6.875  -11.606 1.00 35.95 ? 9   VAL A HG21 1 
ATOM   139  H HG22 . VAL A 1 11  ? 37.247  5.890  -10.364 1.00 35.95 ? 9   VAL A HG22 1 
ATOM   140  H HG23 . VAL A 1 11  ? 38.675  6.374  -10.864 1.00 35.95 ? 9   VAL A HG23 1 
ATOM   141  N N    . LEU A 1 12  ? 40.618  3.590  -11.515 1.00 27.95 ? 10  LEU A N    1 
ATOM   142  C CA   . LEU A 1 12  ? 42.016  3.793  -11.185 1.00 24.04 ? 10  LEU A CA   1 
ATOM   143  C C    . LEU A 1 12  ? 42.548  5.025  -11.874 1.00 24.48 ? 10  LEU A C    1 
ATOM   144  O O    . LEU A 1 12  ? 42.483  5.132  -13.103 1.00 28.41 ? 10  LEU A O    1 
ATOM   145  C CB   . LEU A 1 12  ? 42.848  2.577  -11.585 1.00 25.23 ? 10  LEU A CB   1 
ATOM   146  C CG   . LEU A 1 12  ? 42.338  1.226  -11.096 1.00 34.61 ? 10  LEU A CG   1 
ATOM   147  C CD1  . LEU A 1 12  ? 43.227  0.113  -11.640 1.00 34.37 ? 10  LEU A CD1  1 
ATOM   148  C CD2  . LEU A 1 12  ? 42.295  1.268  -9.574  1.00 29.98 ? 10  LEU A CD2  1 
ATOM   149  H H    . LEU A 1 12  ? 40.503  3.270  -12.305 1.00 33.60 ? 10  LEU A H    1 
ATOM   150  H HA   . LEU A 1 12  ? 42.086  3.933  -10.227 1.00 28.91 ? 10  LEU A HA   1 
ATOM   151  H HB2  . LEU A 1 12  ? 42.879  2.539  -12.554 1.00 30.34 ? 10  LEU A HB2  1 
ATOM   152  H HB3  . LEU A 1 12  ? 43.742  2.693  -11.228 1.00 30.34 ? 10  LEU A HB3  1 
ATOM   153  H HG   . LEU A 1 12  ? 41.443  1.032  -11.415 1.00 41.59 ? 10  LEU A HG   1 
ATOM   154  H HD11 . LEU A 1 12  ? 42.943  -0.733 -11.260 1.00 41.30 ? 10  LEU A HD11 1 
ATOM   155  H HD12 . LEU A 1 12  ? 43.143  0.086  -12.606 1.00 41.30 ? 10  LEU A HD12 1 
ATOM   156  H HD13 . LEU A 1 12  ? 44.147  0.294  -11.393 1.00 41.30 ? 10  LEU A HD13 1 
ATOM   157  H HD21 . LEU A 1 12  ? 42.006  0.404  -9.242  1.00 36.03 ? 10  LEU A HD21 1 
ATOM   158  H HD22 . LEU A 1 12  ? 43.182  1.471  -9.239  1.00 36.03 ? 10  LEU A HD22 1 
ATOM   159  H HD23 . LEU A 1 12  ? 41.671  1.956  -9.295  1.00 36.03 ? 10  LEU A HD23 1 
ATOM   160  N N    . ALA A 1 13  ? 43.068  5.948  -11.075 1.00 22.87 ? 11  ALA A N    1 
ATOM   161  C CA   . ALA A 1 13  ? 43.728  7.118  -11.629 1.00 22.05 ? 11  ALA A CA   1 
ATOM   162  C C    . ALA A 1 13  ? 45.048  6.704  -12.268 1.00 32.53 ? 11  ALA A C    1 
ATOM   163  O O    . ALA A 1 13  ? 45.645  5.690  -11.905 1.00 30.00 ? 11  ALA A O    1 
ATOM   164  C CB   . ALA A 1 13  ? 43.990  8.175  -10.561 1.00 26.14 ? 11  ALA A CB   1 
ATOM   165  H H    . ALA A 1 13  ? 43.052  5.920  -10.216 1.00 27.51 ? 11  ALA A H    1 
ATOM   166  H HA   . ALA A 1 13  ? 43.153  7.521  -12.297 1.00 26.52 ? 11  ALA A HA   1 
ATOM   167  H HB1  . ALA A 1 13  ? 44.460  8.921  -10.965 1.00 31.43 ? 11  ALA A HB1  1 
ATOM   168  H HB2  . ALA A 1 13  ? 43.142  8.475  -10.199 1.00 31.43 ? 11  ALA A HB2  1 
ATOM   169  H HB3  . ALA A 1 13  ? 44.531  7.785  -9.857  1.00 31.43 ? 11  ALA A HB3  1 
ATOM   170  N N    . SER A 1 14  ? 45.460  7.468  -13.275 1.00 33.48 ? 12  SER A N    1 
ATOM   171  C CA   . SER A 1 14  ? 46.718  7.233  -13.976 1.00 31.27 ? 12  SER A CA   1 
ATOM   172  C C    . SER A 1 14  ? 47.902  7.510  -13.059 1.00 34.58 ? 12  SER A C    1 
ATOM   173  O O    . SER A 1 14  ? 47.775  8.099  -11.977 1.00 33.82 ? 12  SER A O    1 
ATOM   174  C CB   . SER A 1 14  ? 46.801  8.109  -15.223 1.00 32.67 ? 12  SER A CB   1 
ATOM   175  O OG   . SER A 1 14  ? 47.119  9.423  -14.843 1.00 39.00 ? 12  SER A OG   1 
ATOM   176  H H    . SER A 1 14  ? 45.022  8.143  -13.578 1.00 40.24 ? 12  SER A H    1 
ATOM   177  H HA   . SER A 1 14  ? 46.760  6.304  -14.251 1.00 37.59 ? 12  SER A HA   1 
ATOM   178  H HB2  . SER A 1 14  ? 47.492  7.768  -15.812 1.00 39.26 ? 12  SER A HB2  1 
ATOM   179  H HB3  . SER A 1 14  ? 45.945  8.104  -15.679 1.00 39.26 ? 12  SER A HB3  1 
ATOM   180  H HG   . SER A 1 14  ? 46.777  9.597  -14.095 1.00 46.86 ? 12  SER A HG   1 
ATOM   181  N N    . SER A 1 15  ? 49.082  7.117  -13.554 1.00 42.25 ? 13  SER A N    1 
ATOM   182  C CA   . SER A 1 15  ? 50.331  7.456  -12.888 1.00 43.53 ? 13  SER A CA   1 
ATOM   183  C C    . SER A 1 15  ? 50.396  8.947  -12.605 1.00 40.05 ? 13  SER A C    1 
ATOM   184  O O    . SER A 1 15  ? 50.841  9.374  -11.536 1.00 44.76 ? 13  SER A O    1 
ATOM   185  C CB   . SER A 1 15  ? 51.514  7.033  -13.766 1.00 44.18 ? 13  SER A CB   1 
ATOM   186  O OG   . SER A 1 15  ? 51.185  7.186  -15.131 1.00 49.49 ? 13  SER A OG   1 
ATOM   187  H H    . SER A 1 15  ? 49.181  6.655  -14.273 1.00 50.76 ? 13  SER A H    1 
ATOM   188  H HA   . SER A 1 15  ? 50.390  6.977  -12.046 1.00 52.29 ? 13  SER A HA   1 
ATOM   189  H HB2  . SER A 1 15  ? 52.280  7.590  -13.558 1.00 53.07 ? 13  SER A HB2  1 
ATOM   190  H HB3  . SER A 1 15  ? 51.723  6.102  -13.591 1.00 53.07 ? 13  SER A HB3  1 
ATOM   191  H HG   . SER A 1 15  ? 51.039  7.996  -15.302 1.00 59.45 ? 13  SER A HG   1 
ATOM   192  N N    . HIS A 1 16  ? 49.991  9.747  -13.562 1.00 42.54 ? 14  HIS A N    1 
ATOM   193  C CA   . HIS A 1 16  ? 50.043  11.202 -13.524 1.00 42.79 ? 14  HIS A CA   1 
ATOM   194  C C    . HIS A 1 16  ? 48.868  11.841 -12.787 1.00 39.04 ? 14  HIS A C    1 
ATOM   195  O O    . HIS A 1 16  ? 48.746  13.064 -12.809 1.00 35.97 ? 14  HIS A O    1 
ATOM   196  C CB   . HIS A 1 16  ? 50.121  11.693 -14.964 1.00 45.68 ? 14  HIS A CB   1 
ATOM   197  C CG   . HIS A 1 16  ? 51.502  11.663 -15.515 1.00 55.79 ? 14  HIS A CG   1 
ATOM   198  N ND1  . HIS A 1 16  ? 51.812  11.083 -16.725 1.00 58.84 ? 14  HIS A ND1  1 
ATOM   199  C CD2  . HIS A 1 16  ? 52.666  12.131 -15.003 1.00 61.10 ? 14  HIS A CD2  1 
ATOM   200  C CE1  . HIS A 1 16  ? 53.111  11.192 -16.934 1.00 53.24 ? 14  HIS A CE1  1 
ATOM   201  N NE2  . HIS A 1 16  ? 53.653  11.821 -15.904 1.00 62.66 ? 14  HIS A NE2  1 
ATOM   202  H H    . HIS A 1 16  ? 49.657  9.459  -14.300 1.00 51.11 ? 14  HIS A H    1 
ATOM   203  N N    . GLY A 1 17  ? 48.056  11.055 -12.094 1.00 39.10 ? 15  GLY A N    1 
ATOM   204  C CA   . GLY A 1 17  ? 47.037  11.582 -11.212 1.00 34.42 ? 15  GLY A CA   1 
ATOM   205  C C    . GLY A 1 17  ? 45.786  12.034 -11.908 1.00 35.91 ? 15  GLY A C    1 
ATOM   206  O O    . GLY A 1 17  ? 45.176  12.990 -11.450 1.00 33.72 ? 15  GLY A O    1 
ATOM   207  H H    . GLY A 1 17  ? 48.078  10.196 -12.120 1.00 46.98 ? 15  GLY A H    1 
ATOM   208  H HA2  . GLY A 1 17  ? 46.790  10.894 -10.574 1.00 41.36 ? 15  GLY A HA2  1 
ATOM   209  H HA3  . GLY A 1 17  ? 47.402  12.342 -10.732 1.00 41.36 ? 15  GLY A HA3  1 
ATOM   210  N N    . VAL A 1 18  ? 45.380  11.363 -12.984 1.00 31.72 ? 16  VAL A N    1 
ATOM   211  C CA   . VAL A 1 18  ? 44.203  11.718 -13.767 1.00 29.65 ? 16  VAL A CA   1 
ATOM   212  C C    . VAL A 1 18  ? 43.231  10.539 -13.747 1.00 29.42 ? 16  VAL A C    1 
ATOM   213  O O    . VAL A 1 18  ? 43.554  9.449  -14.232 1.00 28.07 ? 16  VAL A O    1 
ATOM   214  C CB   . VAL A 1 18  ? 44.578  12.097 -15.210 1.00 33.98 ? 16  VAL A CB   1 
ATOM   215  C CG1  . VAL A 1 18  ? 43.302  12.541 -15.983 1.00 30.28 ? 16  VAL A CG1  1 
ATOM   216  C CG2  . VAL A 1 18  ? 45.611  13.203 -15.221 1.00 33.87 ? 16  VAL A CG2  1 
ATOM   217  H H    . VAL A 1 18  ? 45.789  10.670 -13.290 1.00 38.12 ? 16  VAL A H    1 
ATOM   218  H HA   . VAL A 1 18  ? 43.760  12.474 -13.351 1.00 35.64 ? 16  VAL A HA   1 
ATOM   219  H HB   . VAL A 1 18  ? 44.964  11.325 -15.653 1.00 40.83 ? 16  VAL A HB   1 
ATOM   220  H HG11 . VAL A 1 18  ? 43.547  12.765 -16.895 1.00 36.40 ? 16  VAL A HG11 1 
ATOM   221  H HG12 . VAL A 1 18  ? 42.662  11.812 -15.982 1.00 36.40 ? 16  VAL A HG12 1 
ATOM   222  H HG13 . VAL A 1 18  ? 42.920  13.317 -15.543 1.00 36.40 ? 16  VAL A HG13 1 
ATOM   223  H HG21 . VAL A 1 18  ? 45.910  13.347 -16.133 1.00 40.70 ? 16  VAL A HG21 1 
ATOM   224  H HG22 . VAL A 1 18  ? 45.208  14.015 -14.874 1.00 40.70 ? 16  VAL A HG22 1 
ATOM   225  H HG23 . VAL A 1 18  ? 46.361  12.941 -14.664 1.00 40.70 ? 16  VAL A HG23 1 
ATOM   226  N N    . ALA A 1 19  ? 42.019  10.777 -13.250 1.00 25.69 ? 17  ALA A N    1 
ATOM   227  C CA   . ALA A 1 19  ? 40.946  9.790  -13.261 1.00 24.65 ? 17  ALA A CA   1 
ATOM   228  C C    . ALA A 1 19  ? 39.881  10.268 -14.238 1.00 25.71 ? 17  ALA A C    1 
ATOM   229  O O    . ALA A 1 19  ? 39.532  11.447 -14.244 1.00 25.57 ? 17  ALA A O    1 
ATOM   230  C CB   . ALA A 1 19  ? 40.355  9.612  -11.860 1.00 27.45 ? 17  ALA A CB   1 
ATOM   231  H H    . ALA A 1 19  ? 41.790  11.525 -12.892 1.00 30.89 ? 17  ALA A H    1 
ATOM   232  H HA   . ALA A 1 19  ? 41.277  8.926  -13.552 1.00 29.64 ? 17  ALA A HA   1 
ATOM   233  H HB1  . ALA A 1 19  ? 39.634  8.964  -11.901 1.00 33.00 ? 17  ALA A HB1  1 
ATOM   234  H HB2  . ALA A 1 19  ? 41.050  9.295  -11.262 1.00 33.00 ? 17  ALA A HB2  1 
ATOM   235  H HB3  . ALA A 1 19  ? 40.016  10.465 -11.549 1.00 33.00 ? 17  ALA A HB3  1 
ATOM   236  N N    . SER A 1 20  ? 39.402  9.369  -15.084 1.00 24.61 ? 18  SER A N    1 
ATOM   237  C CA   . SER A 1 20  ? 38.318  9.672  -15.999 1.00 25.21 ? 18  SER A CA   1 
ATOM   238  C C    . SER A 1 20  ? 37.222  8.640  -15.845 1.00 34.12 ? 18  SER A C    1 
ATOM   239  O O    . SER A 1 20  ? 37.497  7.443  -15.769 1.00 27.86 ? 18  SER A O    1 
ATOM   240  C CB   . SER A 1 20  ? 38.780  9.700  -17.445 1.00 29.58 ? 18  SER A CB   1 
ATOM   241  O OG   . SER A 1 20  ? 39.854  10.601 -17.597 1.00 34.50 ? 18  SER A OG   1 
ATOM   242  H H    . SER A 1 20  ? 39.695  8.563  -15.147 1.00 29.60 ? 18  SER A H    1 
ATOM   243  H HA   . SER A 1 20  ? 37.961  10.547 -15.781 1.00 30.31 ? 18  SER A HA   1 
ATOM   244  H HB2  . SER A 1 20  ? 39.072  8.812  -17.703 1.00 35.56 ? 18  SER A HB2  1 
ATOM   245  H HB3  . SER A 1 20  ? 38.044  9.985  -18.009 1.00 35.56 ? 18  SER A HB3  1 
ATOM   246  H HG   . SER A 1 20  ? 40.145  10.571 -18.384 1.00 41.46 ? 18  SER A HG   1 
ATOM   247  N N    . PHE A 1 21  ? 35.976  9.109  -15.814 1.00 25.56 ? 19  PHE A N    1 
ATOM   248  C CA   . PHE A 1 21  ? 34.860  8.181  -15.719 1.00 22.35 ? 19  PHE A CA   1 
ATOM   249  C C    . PHE A 1 21  ? 33.599  8.865  -16.208 1.00 21.82 ? 19  PHE A C    1 
ATOM   250  O O    . PHE A 1 21  ? 33.517  10.094 -16.163 1.00 22.76 ? 19  PHE A O    1 
ATOM   251  C CB   . PHE A 1 21  ? 34.682  7.685  -14.279 1.00 24.51 ? 19  PHE A CB   1 
ATOM   252  C CG   . PHE A 1 21  ? 34.457  8.772  -13.278 1.00 25.04 ? 19  PHE A CG   1 
ATOM   253  C CD1  . PHE A 1 21  ? 35.517  9.412  -12.691 1.00 26.82 ? 19  PHE A CD1  1 
ATOM   254  C CD2  . PHE A 1 21  ? 33.184  9.111  -12.884 1.00 23.24 ? 19  PHE A CD2  1 
ATOM   255  C CE1  . PHE A 1 21  ? 35.326  10.392 -11.769 1.00 25.65 ? 19  PHE A CE1  1 
ATOM   256  C CE2  . PHE A 1 21  ? 32.974  10.097 -11.936 1.00 26.31 ? 19  PHE A CE2  1 
ATOM   257  C CZ   . PHE A 1 21  ? 34.049  10.741 -11.370 1.00 29.26 ? 19  PHE A CZ   1 
ATOM   258  H H    . PHE A 1 21  ? 35.760  9.940  -15.847 1.00 30.73 ? 19  PHE A H    1 
ATOM   259  H HA   . PHE A 1 21  ? 35.026  7.418  -16.294 1.00 26.88 ? 19  PHE A HA   1 
ATOM   260  H HB2  . PHE A 1 21  ? 33.915  7.093  -14.248 1.00 29.48 ? 19  PHE A HB2  1 
ATOM   261  H HB3  . PHE A 1 21  ? 35.483  7.204  -14.016 1.00 29.48 ? 19  PHE A HB3  1 
ATOM   262  H HD1  . PHE A 1 21  ? 36.383  9.170  -12.927 1.00 32.25 ? 19  PHE A HD1  1 
ATOM   263  H HD2  . PHE A 1 21  ? 32.455  8.673  -13.260 1.00 27.95 ? 19  PHE A HD2  1 
ATOM   264  H HE1  . PHE A 1 21  ? 36.059  10.832 -11.404 1.00 30.85 ? 19  PHE A HE1  1 
ATOM   265  H HE2  . PHE A 1 21  ? 32.109  10.323 -11.682 1.00 31.63 ? 19  PHE A HE2  1 
ATOM   266  H HZ   . PHE A 1 21  ? 33.919  11.402 -10.729 1.00 35.17 ? 19  PHE A HZ   1 
ATOM   267  N N    . PRO A 1 22  ? 32.635  8.107  -16.732 1.00 22.70 ? 20  PRO A N    1 
ATOM   268  C CA   . PRO A 1 22  ? 31.357  8.685  -17.139 1.00 23.14 ? 20  PRO A CA   1 
ATOM   269  C C    . PRO A 1 22  ? 30.377  8.771  -15.995 1.00 19.62 ? 20  PRO A C    1 
ATOM   270  O O    . PRO A 1 22  ? 30.407  7.995  -15.035 1.00 19.41 ? 20  PRO A O    1 
ATOM   271  C CB   . PRO A 1 22  ? 30.853  7.692  -18.192 1.00 23.46 ? 20  PRO A CB   1 
ATOM   272  C CG   . PRO A 1 22  ? 31.346  6.386  -17.698 1.00 25.97 ? 20  PRO A CG   1 
ATOM   273  C CD   . PRO A 1 22  ? 32.692  6.673  -17.074 1.00 23.69 ? 20  PRO A CD   1 
ATOM   274  H HA   . PRO A 1 22  ? 31.486  9.564  -17.529 1.00 27.82 ? 20  PRO A HA   1 
ATOM   275  H HB2  . PRO A 1 22  ? 29.884  7.711  -18.235 1.00 28.21 ? 20  PRO A HB2  1 
ATOM   276  H HB3  . PRO A 1 22  ? 31.227  7.905  -19.061 1.00 28.21 ? 20  PRO A HB3  1 
ATOM   277  H HG2  . PRO A 1 22  ? 30.729  6.029  -17.039 1.00 31.23 ? 20  PRO A HG2  1 
ATOM   278  H HG3  . PRO A 1 22  ? 31.434  5.766  -18.439 1.00 31.23 ? 20  PRO A HG3  1 
ATOM   279  H HD2  . PRO A 1 22  ? 32.821  6.136  -16.276 1.00 28.49 ? 20  PRO A HD2  1 
ATOM   280  H HD3  . PRO A 1 22  ? 33.406  6.502  -17.708 1.00 28.49 ? 20  PRO A HD3  1 
ATOM   281  N N    . CYS A 1 23  ? 29.486  9.736  -16.124 1.00 20.49 ? 21  CYS A N    1 
ATOM   282  C CA   . CYS A 1 23  ? 28.346  9.891  -15.250 1.00 15.61 ? 21  CYS A CA   1 
ATOM   283  C C    . CYS A 1 23  ? 27.151  10.112 -16.167 1.00 17.29 ? 21  CYS A C    1 
ATOM   284  O O    . CYS A 1 23  ? 27.186  11.013 -17.004 1.00 18.29 ? 21  CYS A O    1 
ATOM   285  C CB   . CYS A 1 23  ? 28.569  11.047 -14.293 1.00 20.52 ? 21  CYS A CB   1 
ATOM   286  S SG   . CYS A 1 23  ? 27.126  11.348 -13.343 1.00 20.36 ? 21  CYS A SG   1 
ATOM   287  H H    . CYS A 1 23  ? 29.525  10.338 -16.737 1.00 24.64 ? 21  CYS A H    1 
ATOM   288  H HA   . CYS A 1 23  ? 28.177  9.110  -14.700 1.00 18.80 ? 21  CYS A HA   1 
ATOM   289  H HB2  . CYS A 1 23  ? 29.298  10.832 -13.689 1.00 24.68 ? 21  CYS A HB2  1 
ATOM   290  H HB3  . CYS A 1 23  ? 28.782  11.848 -14.797 1.00 24.68 ? 21  CYS A HB3  1 
ATOM   291  N N    . GLU A 1 24  ? 26.110  9.298  -16.018 1.00 17.10 ? 22  GLU A N    1 
ATOM   292  C CA   . GLU A 1 24  ? 25.025  9.217  -16.996 1.00 19.44 ? 22  GLU A CA   1 
ATOM   293  C C    . GLU A 1 24  ? 23.706  9.253  -16.242 1.00 17.28 ? 22  GLU A C    1 
ATOM   294  O O    . GLU A 1 24  ? 23.611  8.740  -15.132 1.00 17.04 ? 22  GLU A O    1 
ATOM   295  C CB   . GLU A 1 24  ? 25.052  7.920  -17.866 1.00 19.85 ? 22  GLU A CB   1 
ATOM   296  H H    . GLU A 1 24  ? 26.006  8.771  -15.346 1.00 20.58 ? 22  GLU A H    1 
ATOM   297  H HA   . GLU A 1 24  ? 25.105  9.971  -17.602 1.00 23.39 ? 22  GLU A HA   1 
ATOM   298  N N    . TYR A 1 25  ? 22.676  9.837  -16.851 1.00 16.69 ? 23  TYR A N    1 
ATOM   299  C CA   . TYR A 1 25  ? 21.370  9.861  -16.216 1.00 15.49 ? 23  TYR A CA   1 
ATOM   300  C C    . TYR A 1 25  ? 20.290  9.329  -17.149 1.00 18.60 ? 23  TYR A C    1 
ATOM   301  O O    . TYR A 1 25  ? 20.413  9.360  -18.377 1.00 17.04 ? 23  TYR A O    1 
ATOM   302  C CB   . TYR A 1 25  ? 20.997  11.279 -15.727 1.00 15.06 ? 23  TYR A CB   1 
ATOM   303  C CG   . TYR A 1 25  ? 20.671  12.277 -16.816 1.00 13.41 ? 23  TYR A CG   1 
ATOM   304  C CD1  . TYR A 1 25  ? 19.383  12.421 -17.315 1.00 15.08 ? 23  TYR A CD1  1 
ATOM   305  C CD2  . TYR A 1 25  ? 21.650  13.126 -17.286 1.00 14.86 ? 23  TYR A CD2  1 
ATOM   306  C CE1  . TYR A 1 25  ? 19.109  13.347 -18.286 1.00 16.76 ? 23  TYR A CE1  1 
ATOM   307  C CE2  . TYR A 1 25  ? 21.407  14.030 -18.240 1.00 16.78 ? 23  TYR A CE2  1 
ATOM   308  C CZ   . TYR A 1 25  ? 20.145  14.171 -18.753 1.00 15.99 ? 23  TYR A CZ   1 
ATOM   309  O OH   . TYR A 1 25  ? 19.930  15.112 -19.743 1.00 17.42 ? 23  TYR A OH   1 
ATOM   310  H H    . TYR A 1 25  ? 22.713  10.219 -17.621 1.00 20.08 ? 23  TYR A H    1 
ATOM   311  H HA   . TYR A 1 25  ? 21.399  9.266  -15.450 1.00 18.65 ? 23  TYR A HA   1 
ATOM   312  H HB2  . TYR A 1 25  ? 20.216  11.209 -15.156 1.00 18.14 ? 23  TYR A HB2  1 
ATOM   313  H HB3  . TYR A 1 25  ? 21.745  11.635 -15.223 1.00 18.14 ? 23  TYR A HB3  1 
ATOM   314  H HD1  . TYR A 1 25  ? 18.699  11.883 -16.987 1.00 18.15 ? 23  TYR A HD1  1 
ATOM   315  H HD2  . TYR A 1 25  ? 22.506  13.067 -16.929 1.00 17.89 ? 23  TYR A HD2  1 
ATOM   316  H HE1  . TYR A 1 25  ? 18.249  13.428 -18.631 1.00 20.17 ? 23  TYR A HE1  1 
ATOM   317  H HE2  . TYR A 1 25  ? 22.098  14.566 -18.556 1.00 20.20 ? 23  TYR A HE2  1 
ATOM   318  H HH   . TYR A 1 25  ? 19.111  15.156 -19.925 1.00 20.96 ? 23  TYR A HH   1 
ATOM   319  N N    . SER A 1 26  ? 19.227  8.816  -16.536 1.00 15.24 ? 24  SER A N    1 
ATOM   320  C CA   . SER A 1 26  ? 18.076  8.343  -17.280 1.00 15.01 ? 24  SER A CA   1 
ATOM   321  C C    . SER A 1 26  ? 16.837  8.557  -16.420 1.00 15.47 ? 24  SER A C    1 
ATOM   322  O O    . SER A 1 26  ? 16.932  8.531  -15.185 1.00 16.22 ? 24  SER A O    1 
ATOM   323  C CB   . SER A 1 26  ? 18.252  6.868  -17.661 1.00 20.30 ? 24  SER A CB   1 
ATOM   324  O OG   . SER A 1 26  ? 18.180  6.130  -16.476 1.00 26.86 ? 24  SER A OG   1 
ATOM   325  H H    . SER A 1 26  ? 19.154  8.732  -15.683 1.00 18.34 ? 24  SER A H    1 
ATOM   326  H HA   . SER A 1 26  ? 17.951  8.851  -18.097 1.00 18.07 ? 24  SER A HA   1 
ATOM   327  H HB2  . SER A 1 26  ? 17.544  6.595  -18.266 1.00 24.42 ? 24  SER A HB2  1 
ATOM   328  H HB3  . SER A 1 26  ? 19.117  6.736  -18.082 1.00 24.42 ? 24  SER A HB3  1 
ATOM   329  H HG   . SER A 1 26  ? 18.431  5.340  -16.614 1.00 32.29 ? 24  SER A HG   1 
ATOM   330  N N    . PRO A 1 27  ? 15.663  8.745  -17.033 1.00 14.39 ? 25  PRO A N    1 
ATOM   331  C CA   . PRO A 1 27  ? 15.426  8.875  -18.465 1.00 15.39 ? 25  PRO A CA   1 
ATOM   332  C C    . PRO A 1 27  ? 15.786  10.275 -18.895 1.00 14.80 ? 25  PRO A C    1 
ATOM   333  O O    . PRO A 1 27  ? 16.108  11.151 -18.093 1.00 13.65 ? 25  PRO A O    1 
ATOM   334  C CB   . PRO A 1 27  ? 13.948  8.591  -18.610 1.00 17.92 ? 25  PRO A CB   1 
ATOM   335  C CG   . PRO A 1 27  ? 13.355  9.120  -17.338 1.00 16.28 ? 25  PRO A CG   1 
ATOM   336  C CD   . PRO A 1 27  ? 14.412  8.882  -16.266 1.00 13.18 ? 25  PRO A CD   1 
ATOM   337  H HA   . PRO A 1 27  ? 15.907  8.208  -18.980 1.00 18.53 ? 25  PRO A HA   1 
ATOM   338  H HB2  . PRO A 1 27  ? 13.592  9.056  -19.383 1.00 21.56 ? 25  PRO A HB2  1 
ATOM   339  H HB3  . PRO A 1 27  ? 13.798  7.637  -18.697 1.00 21.56 ? 25  PRO A HB3  1 
ATOM   340  H HG2  . PRO A 1 27  ? 13.167  10.067 -17.432 1.00 19.60 ? 25  PRO A HG2  1 
ATOM   341  H HG3  . PRO A 1 27  ? 12.539  8.638  -17.131 1.00 19.60 ? 25  PRO A HG3  1 
ATOM   342  H HD2  . PRO A 1 27  ? 14.462  9.637  -15.659 1.00 15.88 ? 25  PRO A HD2  1 
ATOM   343  H HD3  . PRO A 1 27  ? 14.222  8.070  -15.770 1.00 15.88 ? 25  PRO A HD3  1 
ATOM   344  N N    . SER A 1 28  ? 15.669  10.500 -20.192 1.00 13.93 ? 26  SER A N    1 
ATOM   345  C CA   . SER A 1 28  ? 16.072  11.755 -20.797 1.00 16.14 ? 26  SER A CA   1 
ATOM   346  C C    . SER A 1 28  ? 14.832  12.637 -20.862 1.00 16.71 ? 26  SER A C    1 
ATOM   347  O O    . SER A 1 28  ? 14.127  12.701 -21.865 1.00 14.53 ? 26  SER A O    1 
ATOM   348  C CB   . SER A 1 28  ? 16.694  11.498 -22.161 1.00 18.29 ? 26  SER A CB   1 
ATOM   349  O OG   . SER A 1 28  ? 17.255  12.703 -22.637 1.00 25.48 ? 26  SER A OG   1 
ATOM   350  H H    . SER A 1 28  ? 15.354  9.931  -20.754 1.00 16.78 ? 26  SER A H    1 
ATOM   351  H HA   . SER A 1 28  ? 16.738  12.204 -20.253 1.00 19.42 ? 26  SER A HA   1 
ATOM   352  H HB2  . SER A 1 28  ? 17.390  10.827 -22.080 1.00 22.01 ? 26  SER A HB2  1 
ATOM   353  H HB3  . SER A 1 28  ? 16.010  11.194 -22.778 1.00 22.01 ? 26  SER A HB3  1 
ATOM   354  H HG   . SER A 1 28  ? 16.646  13.255 -22.810 1.00 30.63 ? 26  SER A HG   1 
ATOM   355  N N    . HIS A 1 29  ? 14.568  13.322 -19.753 1.00 14.01 ? 27  HIS A N    1 
ATOM   356  C CA   . HIS A 1 29  ? 13.530  14.345 -19.702 1.00 15.40 ? 27  HIS A CA   1 
ATOM   357  C C    . HIS A 1 29  ? 13.947  15.560 -20.498 1.00 16.23 ? 27  HIS A C    1 
ATOM   358  O O    . HIS A 1 29  ? 15.138  15.854 -20.633 1.00 16.00 ? 27  HIS A O    1 
ATOM   359  C CB   . HIS A 1 29  ? 13.238  14.824 -18.275 1.00 16.44 ? 27  HIS A CB   1 
ATOM   360  C CG   . HIS A 1 29  ? 12.821  13.739 -17.351 1.00 13.80 ? 27  HIS A CG   1 
ATOM   361  N ND1  . HIS A 1 29  ? 11.593  13.112 -17.449 1.00 17.32 ? 27  HIS A ND1  1 
ATOM   362  C CD2  . HIS A 1 29  ? 13.423  13.232 -16.253 1.00 17.10 ? 27  HIS A CD2  1 
ATOM   363  C CE1  . HIS A 1 29  ? 11.495  12.211 -16.489 1.00 15.41 ? 27  HIS A CE1  1 
ATOM   364  N NE2  . HIS A 1 29  ? 12.594  12.257 -15.757 1.00 15.25 ? 27  HIS A NE2  1 
ATOM   365  H H    . HIS A 1 29  ? 14.981  13.212 -19.007 1.00 16.87 ? 27  HIS A H    1 
ATOM   366  H HA   . HIS A 1 29  ? 12.723  13.948 -20.066 1.00 18.54 ? 27  HIS A HA   1 
ATOM   367  H HB2  . HIS A 1 29  ? 14.041  15.229 -17.912 1.00 19.79 ? 27  HIS A HB2  1 
ATOM   368  H HB3  . HIS A 1 29  ? 12.522  15.478 -18.306 1.00 19.79 ? 27  HIS A HB3  1 
ATOM   369  H HD2  . HIS A 1 29  ? 14.242  13.494 -15.900 1.00 20.58 ? 27  HIS A HD2  1 
ATOM   370  H HE1  . HIS A 1 29  ? 10.774  11.639 -16.351 1.00 18.55 ? 27  HIS A HE1  1 
ATOM   371  H HE2  . HIS A 1 29  ? 12.763  11.757 -15.079 1.00 18.37 ? 27  HIS A HE2  1 
ATOM   372  N N    . ASN A 1 30  ? 12.946  16.271 -21.046 1.00 17.20 ? 28  ASN A N    1 
ATOM   373  C CA   . ASN A 1 30  ? 13.263  17.546 -21.707 1.00 18.24 ? 28  ASN A CA   1 
ATOM   374  C C    . ASN A 1 30  ? 13.979  18.533 -20.750 1.00 16.11 ? 28  ASN A C    1 
ATOM   375  O O    . ASN A 1 30  ? 13.494  18.889 -19.671 1.00 18.39 ? 28  ASN A O    1 
ATOM   376  C CB   . ASN A 1 30  ? 12.045  18.222 -22.404 1.00 21.83 ? 28  ASN A CB   1 
ATOM   377  C CG   . ASN A 1 30  ? 12.476  19.391 -23.150 1.00 27.88 ? 28  ASN A CG   1 
ATOM   378  O OD1  . ASN A 1 30  ? 12.031  20.560 -22.928 1.00 40.34 ? 28  ASN A OD1  1 
ATOM   379  N ND2  . ASN A 1 30  ? 13.368  19.143 -24.079 1.00 25.22 ? 28  ASN A ND2  1 
ATOM   380  H H    . ASN A 1 30  ? 12.116  16.047 -21.048 1.00 20.70 ? 28  ASN A H    1 
ATOM   381  H HA   . ASN A 1 30  ? 13.878  17.324 -22.423 1.00 21.95 ? 28  ASN A HA   1 
ATOM   382  H HB2  . ASN A 1 30  ? 11.634  17.595 -23.020 1.00 26.26 ? 28  ASN A HB2  1 
ATOM   383  H HB3  . ASN A 1 30  ? 11.400  18.501 -21.735 1.00 26.26 ? 28  ASN A HB3  1 
ATOM   384  H HD21 . ASN A 1 30  ? 13.648  18.339 -24.203 1.00 30.32 ? 28  ASN A HD21 1 
ATOM   385  H HD22 . ASN A 1 30  ? 13.673  19.784 -24.564 1.00 30.32 ? 28  ASN A HD22 1 
ATOM   386  N N    . THR A 1 31  ? 15.148  18.997 -21.188 1.00 15.86 ? 29  THR A N    1 
ATOM   387  C CA   . THR A 1 31  ? 15.824  20.047 -20.433 1.00 17.65 ? 29  THR A CA   1 
ATOM   388  C C    . THR A 1 31  ? 16.749  20.817 -21.357 1.00 16.40 ? 29  THR A C    1 
ATOM   389  O O    . THR A 1 31  ? 17.228  20.278 -22.350 1.00 19.12 ? 29  THR A O    1 
ATOM   390  C CB   . THR A 1 31  ? 16.621  19.445 -19.265 1.00 15.46 ? 29  THR A CB   1 
ATOM   391  O OG1  . THR A 1 31  ? 17.110  20.495 -18.424 1.00 17.19 ? 29  THR A OG1  1 
ATOM   392  C CG2  . THR A 1 31  ? 17.789  18.627 -19.779 1.00 16.98 ? 29  THR A CG2  1 
ATOM   393  H H    . THR A 1 31  ? 15.555  18.728 -21.896 1.00 19.09 ? 29  THR A H    1 
ATOM   394  H HA   . THR A 1 31  ? 15.168  20.671 -20.085 1.00 21.24 ? 29  THR A HA   1 
ATOM   395  H HB   . THR A 1 31  ? 16.044  18.861 -18.749 1.00 18.61 ? 29  THR A HB   1 
ATOM   396  H HG1  . THR A 1 31  ? 16.467  20.940 -18.117 1.00 20.69 ? 29  THR A HG1  1 
ATOM   397  H HG21 . THR A 1 31  ? 18.158  18.087 -19.062 1.00 20.44 ? 29  THR A HG21 1 
ATOM   398  H HG22 . THR A 1 31  ? 17.495  18.041 -20.494 1.00 20.44 ? 29  THR A HG22 1 
ATOM   399  H HG23 . THR A 1 31  ? 18.482  19.215 -20.118 1.00 20.44 ? 29  THR A HG23 1 
ATOM   400  N N    . ASP A 1 32  ? 16.995  22.084 -21.015 1.00 16.79 ? 30  ASP A N    1 
ATOM   401  C CA   . ASP A 1 32  ? 17.931  22.918 -21.764 1.00 20.25 ? 30  ASP A CA   1 
ATOM   402  C C    . ASP A 1 32  ? 19.252  23.147 -21.046 1.00 20.25 ? 30  ASP A C    1 
ATOM   403  O O    . ASP A 1 32  ? 20.180  23.724 -21.635 1.00 17.69 ? 30  ASP A O    1 
ATOM   404  C CB   . ASP A 1 32  ? 17.303  24.278 -22.075 1.00 21.17 ? 30  ASP A CB   1 
ATOM   405  C CG   . ASP A 1 32  ? 16.083  24.149 -22.960 1.00 25.52 ? 30  ASP A CG   1 
ATOM   406  O OD1  . ASP A 1 32  ? 16.145  23.330 -23.919 1.00 28.14 ? 30  ASP A OD1  1 
ATOM   407  O OD2  . ASP A 1 32  ? 15.141  24.940 -22.743 1.00 26.62 ? 30  ASP A OD2  1 
ATOM   408  H H    . ASP A 1 32  ? 16.629  22.483 -20.347 1.00 20.21 ? 30  ASP A H    1 
ATOM   409  H HA   . ASP A 1 32  ? 18.121  22.474 -22.605 1.00 24.36 ? 30  ASP A HA   1 
ATOM   410  H HB2  . ASP A 1 32  ? 17.032  24.702 -21.246 1.00 25.46 ? 30  ASP A HB2  1 
ATOM   411  H HB3  . ASP A 1 32  ? 17.953  24.832 -22.534 1.00 25.46 ? 30  ASP A HB3  1 
ATOM   412  N N    . GLU A 1 33  ? 19.359  22.750 -19.787 1.00 15.02 ? 31  GLU A N    1 
ATOM   413  C CA   . GLU A 1 33  ? 20.518  23.121 -18.995 1.00 16.80 ? 31  GLU A CA   1 
ATOM   414  C C    . GLU A 1 33  ? 20.732  22.025 -17.975 1.00 18.78 ? 31  GLU A C    1 
ATOM   415  O O    . GLU A 1 33  ? 19.832  21.738 -17.171 1.00 14.55 ? 31  GLU A O    1 
ATOM   416  C CB   . GLU A 1 33  ? 20.297  24.477 -18.344 1.00 18.07 ? 31  GLU A CB   1 
ATOM   417  C CG   . GLU A 1 33  ? 21.248  24.870 -17.264 1.00 25.22 ? 31  GLU A CG   1 
ATOM   418  C CD   . GLU A 1 33  ? 21.112  26.357 -16.897 1.00 22.48 ? 31  GLU A CD   1 
ATOM   419  O OE1  . GLU A 1 33  ? 20.611  27.174 -17.735 1.00 27.21 ? 31  GLU A OE1  1 
ATOM   420  O OE2  . GLU A 1 33  ? 21.450  26.679 -15.742 1.00 26.91 ? 31  GLU A OE2  1 
ATOM   421  H H    . GLU A 1 33  ? 18.778  22.270 -19.373 1.00 18.08 ? 31  GLU A H    1 
ATOM   422  H HA   . GLU A 1 33  ? 21.316  23.185 -19.541 1.00 20.23 ? 31  GLU A HA   1 
ATOM   423  H HB2  . GLU A 1 33  ? 20.358  25.155 -19.035 1.00 21.74 ? 31  GLU A HB2  1 
ATOM   424  H HB3  . GLU A 1 33  ? 19.409  24.481 -17.953 1.00 21.74 ? 31  GLU A HB3  1 
ATOM   425  H HG2  . GLU A 1 33  ? 21.066  24.343 -16.470 1.00 30.32 ? 31  GLU A HG2  1 
ATOM   426  H HG3  . GLU A 1 33  ? 22.156  24.712 -17.566 1.00 30.32 ? 31  GLU A HG3  1 
ATOM   427  N N    . VAL A 1 34  ? 21.900  21.377 -18.024 1.00 13.98 ? 32  VAL A N    1 
ATOM   428  C CA   . VAL A 1 34  ? 22.229  20.340 -17.048 1.00 19.78 ? 32  VAL A CA   1 
ATOM   429  C C    . VAL A 1 34  ? 23.452  20.743 -16.244 1.00 19.69 ? 32  VAL A C    1 
ATOM   430  O O    . VAL A 1 34  ? 24.493  21.125 -16.795 1.00 18.74 ? 32  VAL A O    1 
ATOM   431  C CB   . VAL A 1 34  ? 22.412  18.932 -17.658 1.00 24.64 ? 32  VAL A CB   1 
ATOM   432  C CG1  . VAL A 1 34  ? 21.491  18.693 -18.902 1.00 17.48 ? 32  VAL A CG1  1 
ATOM   433  C CG2  . VAL A 1 34  ? 23.807  18.605 -17.893 1.00 32.82 ? 32  VAL A CG2  1 
ATOM   434  H H    . VAL A 1 34  ? 22.513  21.522 -18.610 1.00 16.84 ? 32  VAL A H    1 
ATOM   435  H HA   . VAL A 1 34  ? 21.474  20.294 -16.441 1.00 23.79 ? 32  VAL A HA   1 
ATOM   436  H HB   . VAL A 1 34  ? 22.112  18.292 -16.994 1.00 29.63 ? 32  VAL A HB   1 
ATOM   437  H HG11 . VAL A 1 34  ? 21.544  17.759 -19.160 1.00 21.04 ? 32  VAL A HG11 1 
ATOM   438  H HG12 . VAL A 1 34  ? 20.577  18.919 -18.667 1.00 21.04 ? 32  VAL A HG12 1 
ATOM   439  H HG13 . VAL A 1 34  ? 21.793  19.256 -19.632 1.00 21.04 ? 32  VAL A HG13 1 
ATOM   440  H HG21 . VAL A 1 34  ? 23.856  17.834 -18.478 1.00 39.45 ? 32  VAL A HG21 1 
ATOM   441  H HG22 . VAL A 1 34  ? 24.244  19.365 -18.309 1.00 39.45 ? 32  VAL A HG22 1 
ATOM   442  H HG23 . VAL A 1 34  ? 24.232  18.404 -17.044 1.00 39.45 ? 32  VAL A HG23 1 
ATOM   443  N N    . ARG A 1 35  ? 23.309  20.644 -14.940 1.00 14.04 ? 33  ARG A N    1 
ATOM   444  C CA   . ARG A 1 35  ? 24.299  21.086 -13.978 1.00 14.98 ? 33  ARG A CA   1 
ATOM   445  C C    . ARG A 1 35  ? 24.882  19.826 -13.366 1.00 13.76 ? 33  ARG A C    1 
ATOM   446  O O    . ARG A 1 35  ? 24.136  18.940 -12.922 1.00 13.85 ? 33  ARG A O    1 
ATOM   447  C CB   . ARG A 1 35  ? 23.664  22.022 -12.951 1.00 14.21 ? 33  ARG A CB   1 
ATOM   448  C CG   . ARG A 1 35  ? 24.685  22.788 -12.201 1.00 14.53 ? 33  ARG A CG   1 
ATOM   449  C CD   . ARG A 1 35  ? 24.085  23.659 -11.134 1.00 16.00 ? 33  ARG A CD   1 
ATOM   450  N NE   . ARG A 1 35  ? 25.104  24.312 -10.319 1.00 15.27 ? 33  ARG A NE   1 
ATOM   451  C CZ   . ARG A 1 35  ? 25.400  23.937 -9.078  1.00 18.29 ? 33  ARG A CZ   1 
ATOM   452  N NH1  . ARG A 1 35  ? 24.967  22.789 -8.583  1.00 14.15 ? 33  ARG A NH1  1 
ATOM   453  N NH2  . ARG A 1 35  ? 26.323  24.611 -8.395  1.00 21.39 ? 33  ARG A NH2  1 
ATOM   454  H H    . ARG A 1 35  ? 22.611  20.308 -14.567 1.00 16.91 ? 33  ARG A H    1 
ATOM   455  H HA   . ARG A 1 35  ? 25.021  21.588 -14.387 1.00 18.03 ? 33  ARG A HA   1 
ATOM   456  H HB2  . ARG A 1 35  ? 23.085  22.652 -13.408 1.00 17.12 ? 33  ARG A HB2  1 
ATOM   457  H HB3  . ARG A 1 35  ? 23.150  21.498 -12.317 1.00 17.12 ? 33  ARG A HB3  1 
ATOM   458  H HG2  . ARG A 1 35  ? 25.296  22.168 -11.774 1.00 17.49 ? 33  ARG A HG2  1 
ATOM   459  H HG3  . ARG A 1 35  ? 25.169  23.359 -12.818 1.00 17.49 ? 33  ARG A HG3  1 
ATOM   460  H HD2  . ARG A 1 35  ? 23.545  24.348 -11.552 1.00 19.27 ? 33  ARG A HD2  1 
ATOM   461  H HD3  . ARG A 1 35  ? 23.534  23.114 -10.550 1.00 19.27 ? 33  ARG A HD3  1 
ATOM   462  H HE   . ARG A 1 35  ? 25.535  24.974 -10.659 1.00 18.39 ? 33  ARG A HE   1 
ATOM   463  H HH11 . ARG A 1 35  ? 24.483  22.268 -9.067  1.00 17.04 ? 33  ARG A HH11 1 
ATOM   464  H HH12 . ARG A 1 35  ? 25.169  22.564 -7.778  1.00 17.04 ? 33  ARG A HH12 1 
ATOM   465  H HH21 . ARG A 1 35  ? 26.721  25.282 -8.757  1.00 25.73 ? 33  ARG A HH21 1 
ATOM   466  H HH22 . ARG A 1 35  ? 26.521  24.376 -7.592  1.00 25.73 ? 33  ARG A HH22 1 
ATOM   467  N N    . VAL A 1 36  ? 26.199  19.692 -13.447 1.00 13.98 ? 34  VAL A N    1 
ATOM   468  C CA   . VAL A 1 36  ? 26.899  18.533 -12.911 1.00 13.25 ? 34  VAL A CA   1 
ATOM   469  C C    . VAL A 1 36  ? 27.814  18.983 -11.783 1.00 14.28 ? 34  VAL A C    1 
ATOM   470  O O    . VAL A 1 36  ? 28.559  19.959 -11.936 1.00 17.07 ? 34  VAL A O    1 
ATOM   471  C CB   . VAL A 1 36  ? 27.689  17.785 -14.004 1.00 13.46 ? 34  VAL A CB   1 
ATOM   472  C CG1  . VAL A 1 36  ? 28.386  16.579 -13.435 1.00 21.31 ? 34  VAL A CG1  1 
ATOM   473  C CG2  . VAL A 1 36  ? 26.774  17.422 -15.152 1.00 18.16 ? 34  VAL A CG2  1 
ATOM   474  H H    . VAL A 1 36  ? 26.718  20.271 -13.815 1.00 16.83 ? 34  VAL A H    1 
ATOM   475  H HA   . VAL A 1 36  ? 26.248  17.920 -12.534 1.00 15.96 ? 34  VAL A HA   1 
ATOM   476  H HB   . VAL A 1 36  ? 28.382  18.368 -14.354 1.00 16.22 ? 34  VAL A HB   1 
ATOM   477  H HG11 . VAL A 1 36  ? 28.833  16.105 -14.153 1.00 25.63 ? 34  VAL A HG11 1 
ATOM   478  H HG12 . VAL A 1 36  ? 29.035  16.871 -12.776 1.00 25.63 ? 34  VAL A HG12 1 
ATOM   479  H HG13 . VAL A 1 36  ? 27.727  16.002 -13.017 1.00 25.63 ? 34  VAL A HG13 1 
ATOM   480  H HG21 . VAL A 1 36  ? 27.274  16.906 -15.804 1.00 21.86 ? 34  VAL A HG21 1 
ATOM   481  H HG22 . VAL A 1 36  ? 26.034  16.895 -14.811 1.00 21.86 ? 34  VAL A HG22 1 
ATOM   482  H HG23 . VAL A 1 36  ? 26.440  18.236 -15.559 1.00 21.86 ? 34  VAL A HG23 1 
ATOM   483  N N    . THR A 1 37  ? 27.806  18.246 -10.671 1.00 13.57 ? 35  THR A N    1 
ATOM   484  C CA   . THR A 1 37  ? 28.669  18.534 -9.539  1.00 14.23 ? 35  THR A CA   1 
ATOM   485  C C    . THR A 1 37  ? 29.367  17.246 -9.167  1.00 15.65 ? 35  THR A C    1 
ATOM   486  O O    . THR A 1 37  ? 28.754  16.172 -9.175  1.00 14.63 ? 35  THR A O    1 
ATOM   487  C CB   . THR A 1 37  ? 27.910  19.019 -8.318  1.00 15.26 ? 35  THR A CB   1 
ATOM   488  O OG1  . THR A 1 37  ? 27.056  20.109 -8.661  1.00 16.32 ? 35  THR A OG1  1 
ATOM   489  C CG2  . THR A 1 37  ? 28.830  19.524 -7.258  1.00 17.40 ? 35  THR A CG2  1 
ATOM   490  H H    . THR A 1 37  ? 27.298  17.562 -10.553 1.00 16.35 ? 35  THR A H    1 
ATOM   491  H HA   . THR A 1 37  ? 29.299  19.228 -9.790  1.00 17.13 ? 35  THR A HA   1 
ATOM   492  H HB   . THR A 1 37  ? 27.401  18.265 -7.981  1.00 18.37 ? 35  THR A HB   1 
ATOM   493  H HG1  . THR A 1 37  ? 26.671  20.400 -7.973  1.00 19.64 ? 35  THR A HG1  1 
ATOM   494  H HG21 . THR A 1 37  ? 28.318  19.918 -6.535  1.00 20.94 ? 35  THR A HG21 1 
ATOM   495  H HG22 . THR A 1 37  ? 29.362  18.793 -6.905  1.00 20.94 ? 35  THR A HG22 1 
ATOM   496  H HG23 . THR A 1 37  ? 29.423  20.196 -7.627  1.00 20.94 ? 35  THR A HG23 1 
ATOM   497  N N    . VAL A 1 38  ? 30.650  17.347 -8.848  1.00 12.56 ? 36  VAL A N    1 
ATOM   498  C CA   . VAL A 1 38  ? 31.398  16.229 -8.305  1.00 16.30 ? 36  VAL A CA   1 
ATOM   499  C C    . VAL A 1 38  ? 31.596  16.581 -6.831  1.00 17.80 ? 36  VAL A C    1 
ATOM   500  O O    . VAL A 1 38  ? 32.090  17.662 -6.498  1.00 17.50 ? 36  VAL A O    1 
ATOM   501  C CB   . VAL A 1 38  ? 32.722  15.995 -9.057  1.00 15.94 ? 36  VAL A CB   1 
ATOM   502  C CG1  . VAL A 1 38  ? 33.513  14.908 -8.364  1.00 18.25 ? 36  VAL A CG1  1 
ATOM   503  C CG2  . VAL A 1 38  ? 32.471  15.619 -10.498 1.00 17.15 ? 36  VAL A CG2  1 
ATOM   504  H H    . VAL A 1 38  ? 31.113  18.066 -8.939  1.00 15.14 ? 36  VAL A H    1 
ATOM   505  H HA   . VAL A 1 38  ? 30.909  15.395 -8.376  1.00 19.62 ? 36  VAL A HA   1 
ATOM   506  H HB   . VAL A 1 38  ? 33.236  16.818 -9.054  1.00 19.19 ? 36  VAL A HB   1 
ATOM   507  H HG11 . VAL A 1 38  ? 34.129  14.512 -8.999  1.00 21.96 ? 36  VAL A HG11 1 
ATOM   508  H HG12 . VAL A 1 38  ? 34.005  15.298 -7.625  1.00 21.96 ? 36  VAL A HG12 1 
ATOM   509  H HG13 . VAL A 1 38  ? 32.899  14.234 -8.033  1.00 21.96 ? 36  VAL A HG13 1 
ATOM   510  H HG21 . VAL A 1 38  ? 33.317  15.399 -10.919 1.00 20.64 ? 36  VAL A HG21 1 
ATOM   511  H HG22 . VAL A 1 38  ? 31.879  14.851 -10.525 1.00 20.64 ? 36  VAL A HG22 1 
ATOM   512  H HG23 . VAL A 1 38  ? 32.060  16.370 -10.953 1.00 20.64 ? 36  VAL A HG23 1 
ATOM   513  N N    . LEU A 1 39  ? 31.171  15.697 -5.952  1.00 14.91 ? 37  LEU A N    1 
ATOM   514  C CA   . LEU A 1 39  ? 31.328  15.882 -4.517  1.00 21.00 ? 37  LEU A CA   1 
ATOM   515  C C    . LEU A 1 39  ? 32.185  14.762 -3.943  1.00 19.76 ? 37  LEU A C    1 
ATOM   516  O O    . LEU A 1 39  ? 32.025  13.593 -4.309  1.00 19.49 ? 37  LEU A O    1 
ATOM   517  C CB   . LEU A 1 39  ? 29.961  15.908 -3.785  1.00 19.90 ? 37  LEU A CB   1 
ATOM   518  C CG   . LEU A 1 39  ? 28.949  16.950 -4.265  1.00 18.84 ? 37  LEU A CG   1 
ATOM   519  C CD1  . LEU A 1 39  ? 27.526  16.516 -3.983  1.00 24.79 ? 37  LEU A CD1  1 
ATOM   520  C CD2  . LEU A 1 39  ? 29.217  18.308 -3.671  1.00 25.25 ? 37  LEU A CD2  1 
ATOM   521  H H    . LEU A 1 39  ? 30.777  14.962 -6.163  1.00 17.96 ? 37  LEU A H    1 
ATOM   522  H HA   . LEU A 1 39  ? 31.772  16.730 -4.360  1.00 25.27 ? 37  LEU A HA   1 
ATOM   523  H HB2  . LEU A 1 39  ? 29.547  15.037 -3.891  1.00 23.94 ? 37  LEU A HB2  1 
ATOM   524  H HB3  . LEU A 1 39  ? 30.127  16.083 -2.845  1.00 23.94 ? 37  LEU A HB3  1 
ATOM   525  H HG   . LEU A 1 39  ? 29.050  17.028 -5.226  1.00 22.67 ? 37  LEU A HG   1 
ATOM   526  H HD11 . LEU A 1 39  ? 26.940  17.285 -4.058  1.00 29.81 ? 37  LEU A HD11 1 
ATOM   527  H HD12 . LEU A 1 39  ? 27.268  15.839 -4.628  1.00 29.81 ? 37  LEU A HD12 1 
ATOM   528  H HD13 . LEU A 1 39  ? 27.479  16.152 -3.085  1.00 29.81 ? 37  LEU A HD13 1 
ATOM   529  H HD21 . LEU A 1 39  ? 28.877  18.989 -4.273  1.00 30.36 ? 37  LEU A HD21 1 
ATOM   530  H HD22 . LEU A 1 39  ? 28.769  18.372 -2.813  1.00 30.36 ? 37  LEU A HD22 1 
ATOM   531  H HD23 . LEU A 1 39  ? 30.173  18.419 -3.554  1.00 30.36 ? 37  LEU A HD23 1 
ATOM   532  N N    . ARG A 1 40  ? 33.056  15.112 -3.007  1.00 24.61 ? 38  ARG A N    1 
ATOM   533  C CA   . ARG A 1 40  ? 33.892  14.116 -2.355  1.00 24.52 ? 38  ARG A CA   1 
ATOM   534  C C    . ARG A 1 40  ? 33.441  13.911 -0.922  1.00 24.41 ? 38  ARG A C    1 
ATOM   535  O O    . ARG A 1 40  ? 33.319  14.866 -0.160  1.00 26.79 ? 38  ARG A O    1 
ATOM   536  C CB   . ARG A 1 40  ? 35.361  14.509 -2.395  1.00 27.64 ? 38  ARG A CB   1 
ATOM   537  C CG   . ARG A 1 40  ? 36.298  13.326 -2.185  1.00 31.80 ? 38  ARG A CG   1 
ATOM   538  C CD   . ARG A 1 40  ? 37.284  13.603 -1.074  1.00 39.45 ? 38  ARG A CD   1 
ATOM   539  N NE   . ARG A 1 40  ? 38.536  12.889 -1.269  1.00 37.82 ? 38  ARG A NE   1 
ATOM   540  C CZ   . ARG A 1 40  ? 39.401  12.635 -0.304  1.00 43.04 ? 38  ARG A CZ   1 
ATOM   541  N NH1  . ARG A 1 40  ? 39.161  12.993 0.948   1.00 49.70 ? 38  ARG A NH1  1 
ATOM   542  N NH2  . ARG A 1 40  ? 40.532  12.008 -0.601  1.00 39.32 ? 38  ARG A NH2  1 
ATOM   543  H H    . ARG A 1 40  ? 33.180  15.918 -2.734  1.00 29.60 ? 38  ARG A H    1 
ATOM   544  H HA   . ARG A 1 40  ? 33.791  13.272 -2.823  1.00 29.49 ? 38  ARG A HA   1 
ATOM   545  H HB2  . ARG A 1 40  ? 35.560  14.898 -3.261  1.00 33.23 ? 38  ARG A HB2  1 
ATOM   546  H HB3  . ARG A 1 40  ? 35.533  15.156 -1.693  1.00 33.23 ? 38  ARG A HB3  1 
ATOM   547  H HG2  . ARG A 1 40  ? 35.779  12.542 -1.945  1.00 38.22 ? 38  ARG A HG2  1 
ATOM   548  H HG3  . ARG A 1 40  ? 36.794  13.158 -3.001  1.00 38.22 ? 38  ARG A HG3  1 
ATOM   549  H HD2  . ARG A 1 40  ? 37.477  14.554 -1.049  1.00 47.40 ? 38  ARG A HD2  1 
ATOM   550  H HD3  . ARG A 1 40  ? 36.901  13.320 -0.229  1.00 47.40 ? 38  ARG A HD3  1 
ATOM   551  H HE   . ARG A 1 40  ? 38.725  12.615 -2.062  1.00 45.45 ? 38  ARG A HE   1 
ATOM   552  H HH11 . ARG A 1 40  ? 38.430  13.400 1.146   1.00 59.70 ? 38  ARG A HH11 1 
ATOM   553  H HH12 . ARG A 1 40  ? 39.737  12.819 1.563   1.00 59.70 ? 38  ARG A HH12 1 
ATOM   554  H HH21 . ARG A 1 40  ? 40.693  11.773 -1.413  1.00 47.25 ? 38  ARG A HH21 1 
ATOM   555  H HH22 . ARG A 1 40  ? 41.104  11.836 0.018   1.00 47.25 ? 38  ARG A HH22 1 
ATOM   556  N N    . GLN A 1 41  ? 33.221  12.650 -0.559  1.00 28.58 ? 39  GLN A N    1 
ATOM   557  C CA   . GLN A 1 41  ? 32.712  12.269 0.757   1.00 34.62 ? 39  GLN A CA   1 
ATOM   558  C C    . GLN A 1 41  ? 33.770  11.889 1.804   1.00 37.48 ? 39  GLN A C    1 
ATOM   559  O O    . GLN A 1 41  ? 34.861  12.457 1.843   1.00 48.45 ? 39  GLN A O    1 
ATOM   560  C CB   . GLN A 1 41  ? 31.765  11.088 0.598   1.00 41.16 ? 39  GLN A CB   1 
ATOM   561  C CG   . GLN A 1 41  ? 30.389  11.264 1.181   1.00 42.69 ? 39  GLN A CG   1 
ATOM   562  C CD   . GLN A 1 41  ? 29.466  10.119 0.803   1.00 43.48 ? 39  GLN A CD   1 
ATOM   563  O OE1  . GLN A 1 41  ? 29.729  8.970  1.141   1.00 51.73 ? 39  GLN A OE1  1 
ATOM   564  N NE2  . GLN A 1 41  ? 28.366  10.432 0.138   1.00 59.86 ? 39  GLN A NE2  1 
ATOM   565  N N    . MET A 1 46  ? 30.794  16.395 3.206   1.00 40.51 ? 44  MET A N    1 
ATOM   566  C CA   . MET A 1 46  ? 30.824  16.477 1.759   1.00 31.97 ? 44  MET A CA   1 
ATOM   567  C C    . MET A 1 46  ? 31.546  17.745 1.321   1.00 32.88 ? 44  MET A C    1 
ATOM   568  O O    . MET A 1 46  ? 31.250  18.831 1.815   1.00 35.40 ? 44  MET A O    1 
ATOM   569  C CB   . MET A 1 46  ? 29.407  16.474 1.187   1.00 36.16 ? 44  MET A CB   1 
ATOM   570  C CG   . MET A 1 46  ? 29.367  16.068 -0.257  1.00 33.02 ? 44  MET A CG   1 
ATOM   571  S SD   . MET A 1 46  ? 29.685  14.305 -0.380  1.00 40.88 ? 44  MET A SD   1 
ATOM   572  C CE   . MET A 1 46  ? 28.527  13.648 0.803   1.00 41.21 ? 44  MET A CE   1 
ATOM   573  H H    . MET A 1 46  ? 30.047  16.679 3.522   1.00 48.67 ? 44  MET A H    1 
ATOM   574  N N    . THR A 1 47  ? 32.498  17.602 0.402   1.00 27.52 ? 45  THR A N    1 
ATOM   575  C CA   . THR A 1 47  ? 33.206  18.731 -0.171  1.00 27.52 ? 45  THR A CA   1 
ATOM   576  C C    . THR A 1 47  ? 32.883  18.806 -1.652  1.00 25.22 ? 45  THR A C    1 
ATOM   577  O O    . THR A 1 47  ? 32.720  17.781 -2.319  1.00 25.14 ? 45  THR A O    1 
ATOM   578  C CB   . THR A 1 47  ? 34.722  18.616 -0.000  1.00 28.96 ? 45  THR A CB   1 
ATOM   579  O OG1  . THR A 1 47  ? 35.212  17.520 -0.776  1.00 36.68 ? 45  THR A OG1  1 
ATOM   580  C CG2  . THR A 1 47  ? 35.093  18.382 1.473   1.00 34.43 ? 45  THR A CG2  1 
ATOM   581  H H    . THR A 1 47  ? 32.753  16.842 0.090   1.00 33.09 ? 45  THR A H    1 
ATOM   582  H HA   . THR A 1 47  ? 32.921  19.545 0.274   1.00 33.09 ? 45  THR A HA   1 
ATOM   583  H HB   . THR A 1 47  ? 35.137  19.442 -0.296  1.00 34.81 ? 45  THR A HB   1 
ATOM   584  H HG1  . THR A 1 47  ? 36.033  17.411 -0.634  1.00 44.08 ? 45  THR A HG1  1 
ATOM   585  H HG21 . THR A 1 47  ? 36.054  18.293 1.564   1.00 41.38 ? 45  THR A HG21 1 
ATOM   586  H HG22 . THR A 1 47  ? 34.793  19.130 2.013   1.00 41.38 ? 45  THR A HG22 1 
ATOM   587  H HG23 . THR A 1 47  ? 34.670  17.571 1.797   1.00 41.38 ? 45  THR A HG23 1 
ATOM   588  N N    . GLU A 1 48  ? 32.817  20.029 -2.165  1.00 23.51 ? 46  GLU A N    1 
ATOM   589  C CA   . GLU A 1 48  ? 32.611  20.270 -3.582  1.00 23.11 ? 46  GLU A CA   1 
ATOM   590  C C    . GLU A 1 48  ? 33.946  20.241 -4.317  1.00 29.22 ? 46  GLU A C    1 
ATOM   591  O O    . GLU A 1 48  ? 34.817  21.069 -4.059  1.00 30.57 ? 46  GLU A O    1 
ATOM   592  C CB   . GLU A 1 48  ? 31.920  21.613 -3.777  1.00 26.31 ? 46  GLU A CB   1 
ATOM   593  C CG   . GLU A 1 48  ? 31.451  21.879 -5.180  1.00 29.01 ? 46  GLU A CG   1 
ATOM   594  C CD   . GLU A 1 48  ? 30.900  23.290 -5.315  1.00 31.50 ? 46  GLU A CD   1 
ATOM   595  O OE1  . GLU A 1 48  ? 31.645  24.257 -5.051  1.00 35.64 ? 46  GLU A OE1  1 
ATOM   596  O OE2  . GLU A 1 48  ? 29.704  23.415 -5.617  1.00 34.64 ? 46  GLU A OE2  1 
ATOM   597  H H    . GLU A 1 48  ? 32.890  20.749 -1.700  1.00 28.28 ? 46  GLU A H    1 
ATOM   598  H HA   . GLU A 1 48  ? 32.057  19.566 -3.954  1.00 27.80 ? 46  GLU A HA   1 
ATOM   599  H HB2  . GLU A 1 48  ? 31.143  21.647 -3.198  1.00 31.63 ? 46  GLU A HB2  1 
ATOM   600  H HB3  . GLU A 1 48  ? 32.543  22.317 -3.539  1.00 31.63 ? 46  GLU A HB3  1 
ATOM   601  H HG2  . GLU A 1 48  ? 32.196  21.781 -5.794  1.00 34.87 ? 46  GLU A HG2  1 
ATOM   602  H HG3  . GLU A 1 48  ? 30.748  21.251 -5.410  1.00 34.87 ? 46  GLU A HG3  1 
ATOM   603  N N    . VAL A 1 49  ? 34.101  19.280 -5.227  1.00 20.63 ? 47  VAL A N    1 
ATOM   604  C CA   . VAL A 1 49  ? 35.290  19.212 -6.065  1.00 17.75 ? 47  VAL A CA   1 
ATOM   605  C C    . VAL A 1 49  ? 35.188  20.189 -7.235  1.00 23.43 ? 47  VAL A C    1 
ATOM   606  O O    . VAL A 1 49  ? 36.076  21.023 -7.445  1.00 26.03 ? 47  VAL A O    1 
ATOM   607  C CB   . VAL A 1 49  ? 35.500  17.769 -6.545  1.00 22.49 ? 47  VAL A CB   1 
ATOM   608  C CG1  . VAL A 1 49  ? 36.704  17.689 -7.475  1.00 25.25 ? 47  VAL A CG1  1 
ATOM   609  C CG2  . VAL A 1 49  ? 35.620  16.836 -5.350  1.00 27.91 ? 47  VAL A CG2  1 
ATOM   610  H H    . VAL A 1 49  ? 33.530  18.655 -5.377  1.00 24.81 ? 47  VAL A H    1 
ATOM   611  H HA   . VAL A 1 49  ? 36.062  19.473 -5.539  1.00 21.37 ? 47  VAL A HA   1 
ATOM   612  H HB   . VAL A 1 49  ? 34.732  17.474 -7.059  1.00 27.04 ? 47  VAL A HB   1 
ATOM   613  H HG11 . VAL A 1 49  ? 36.970  16.761 -7.568  1.00 30.36 ? 47  VAL A HG11 1 
ATOM   614  H HG12 . VAL A 1 49  ? 36.459  18.051 -8.341  1.00 30.36 ? 47  VAL A HG12 1 
ATOM   615  H HG13 . VAL A 1 49  ? 37.432  18.205 -7.094  1.00 30.36 ? 47  VAL A HG13 1 
ATOM   616  H HG21 . VAL A 1 49  ? 35.779  15.934 -5.669  1.00 33.55 ? 47  VAL A HG21 1 
ATOM   617  H HG22 . VAL A 1 49  ? 36.362  17.127 -4.796  1.00 33.55 ? 47  VAL A HG22 1 
ATOM   618  H HG23 . VAL A 1 49  ? 34.795  16.867 -4.841  1.00 33.55 ? 47  VAL A HG23 1 
ATOM   619  N N    . CYS A 1 50  ? 34.093  20.116 -7.998  1.00 20.04 ? 48  CYS A N    1 
ATOM   620  C CA   . CYS A 1 50  ? 33.855  21.010 -9.113  1.00 18.79 ? 48  CYS A CA   1 
ATOM   621  C C    . CYS A 1 50  ? 32.388  20.938 -9.491  1.00 23.34 ? 48  CYS A C    1 
ATOM   622  O O    . CYS A 1 50  ? 31.686  19.976 -9.166  1.00 18.55 ? 48  CYS A O    1 
ATOM   623  C CB   . CYS A 1 50  ? 34.706  20.639 -10.312 1.00 20.16 ? 48  CYS A CB   1 
ATOM   624  S SG   . CYS A 1 50  ? 34.758  18.895 -10.639 1.00 24.95 ? 48  CYS A SG   1 
ATOM   625  H H    . CYS A 1 50  ? 33.464  19.542 -7.881  1.00 24.11 ? 48  CYS A H    1 
ATOM   626  H HA   . CYS A 1 50  ? 34.067  21.917 -8.842  1.00 22.60 ? 48  CYS A HA   1 
ATOM   627  H HB2  . CYS A 1 50  ? 34.345  21.077 -11.098 1.00 24.25 ? 48  CYS A HB2  1 
ATOM   628  H HB3  . CYS A 1 50  ? 35.615  20.938 -10.153 1.00 24.25 ? 48  CYS A HB3  1 
ATOM   629  N N    . ALA A 1 51  ? 31.960  21.955 -10.226 1.00 20.23 ? 49  ALA A N    1 
ATOM   630  C CA   . ALA A 1 51  ? 30.583  22.060 -10.691 1.00 18.02 ? 49  ALA A CA   1 
ATOM   631  C C    . ALA A 1 51  ? 30.595  22.820 -12.007 1.00 19.79 ? 49  ALA A C    1 
ATOM   632  O O    . ALA A 1 51  ? 31.488  23.636 -12.263 1.00 21.42 ? 49  ALA A O    1 
ATOM   633  C CB   . ALA A 1 51  ? 29.703  22.762 -9.670  1.00 19.07 ? 49  ALA A CB   1 
ATOM   634  H H    . ALA A 1 51  ? 32.457  22.612 -10.474 1.00 24.33 ? 49  ALA A H    1 
ATOM   635  H HA   . ALA A 1 51  ? 30.206  21.180 -10.844 1.00 21.69 ? 49  ALA A HA   1 
ATOM   636  H HB1  . ALA A 1 51  ? 28.799  22.816 -10.015 1.00 22.95 ? 49  ALA A HB1  1 
ATOM   637  H HB2  . ALA A 1 51  ? 29.712  22.254 -8.843  1.00 22.95 ? 49  ALA A HB2  1 
ATOM   638  H HB3  . ALA A 1 51  ? 30.051  23.654 -9.513  1.00 22.95 ? 49  ALA A HB3  1 
ATOM   639  N N    . THR A 1 52  ? 29.640  22.507 -12.872 1.00 18.19 ? 50  THR A N    1 
ATOM   640  C CA   . THR A 1 52  ? 29.543  23.218 -14.140 1.00 19.11 ? 50  THR A CA   1 
ATOM   641  C C    . THR A 1 52  ? 28.143  23.049 -14.694 1.00 18.39 ? 50  THR A C    1 
ATOM   642  O O    . THR A 1 52  ? 27.439  22.093 -14.361 1.00 16.11 ? 50  THR A O    1 
ATOM   643  C CB   . THR A 1 52  ? 30.536  22.711 -15.192 1.00 21.72 ? 50  THR A CB   1 
ATOM   644  O OG1  . THR A 1 52  ? 30.669  23.669 -16.250 1.00 21.40 ? 50  THR A OG1  1 
ATOM   645  C CG2  . THR A 1 52  ? 30.047  21.404 -15.770 1.00 18.87 ? 50  THR A CG2  1 
ATOM   646  H H    . THR A 1 52  ? 29.046  21.897 -12.751 1.00 21.88 ? 50  THR A H    1 
ATOM   647  H HA   . THR A 1 52  ? 29.725  24.153 -13.959 1.00 22.99 ? 50  THR A HA   1 
ATOM   648  H HB   . THR A 1 52  ? 31.402  22.575 -14.777 1.00 26.12 ? 50  THR A HB   1 
ATOM   649  H HG1  . THR A 1 52  ? 30.622  23.283 -16.994 1.00 25.74 ? 50  THR A HG1  1 
ATOM   650  H HG21 . THR A 1 52  ? 30.786  20.923 -16.176 1.00 22.70 ? 50  THR A HG21 1 
ATOM   651  H HG22 . THR A 1 52  ? 29.660  20.855 -15.070 1.00 22.70 ? 50  THR A HG22 1 
ATOM   652  H HG23 . THR A 1 52  ? 29.372  21.572 -16.447 1.00 22.70 ? 50  THR A HG23 1 
ATOM   653  N N    . THR A 1 53  ? 27.779  23.944 -15.611 1.00 17.67 ? 51  THR A N    1 
ATOM   654  C CA   . THR A 1 53  ? 26.491  23.897 -16.281 1.00 19.51 ? 51  THR A CA   1 
ATOM   655  C C    . THR A 1 53  ? 26.716  23.684 -17.768 1.00 25.17 ? 51  THR A C    1 
ATOM   656  O O    . THR A 1 53  ? 27.459  24.454 -18.393 1.00 25.48 ? 51  THR A O    1 
ATOM   657  C CB   . THR A 1 53  ? 25.731  25.200 -16.033 1.00 24.19 ? 51  THR A CB   1 
ATOM   658  O OG1  . THR A 1 53  ? 25.346  25.251 -14.656 1.00 23.94 ? 51  THR A OG1  1 
ATOM   659  C CG2  . THR A 1 53  ? 24.506  25.201 -16.881 1.00 27.44 ? 51  THR A CG2  1 
ATOM   660  H H    . THR A 1 53  ? 28.276  24.600 -15.863 1.00 21.27 ? 51  THR A H    1 
ATOM   661  H HA   . THR A 1 53  ? 25.959  23.156 -15.951 1.00 23.47 ? 51  THR A HA   1 
ATOM   662  H HB   . THR A 1 53  ? 26.277  25.973 -16.248 1.00 29.08 ? 51  THR A HB   1 
ATOM   663  H HG1  . THR A 1 53  ? 24.849  25.915 -14.521 1.00 28.78 ? 51  THR A HG1  1 
ATOM   664  H HG21 . THR A 1 53  ? 23.982  25.998 -16.706 1.00 32.99 ? 51  THR A HG21 1 
ATOM   665  H HG22 . THR A 1 53  ? 24.751  25.185 -17.819 1.00 32.99 ? 51  THR A HG22 1 
ATOM   666  H HG23 . THR A 1 53  ? 23.966  24.420 -16.684 1.00 32.99 ? 51  THR A HG23 1 
ATOM   667  N N    . PHE A 1 54  ? 26.090  22.656 -18.334 1.00 21.34 ? 52  PHE A N    1 
ATOM   668  C CA   . PHE A 1 54  ? 26.139  22.379 -19.758 1.00 20.70 ? 52  PHE A CA   1 
ATOM   669  C C    . PHE A 1 54  ? 24.871  22.883 -20.423 1.00 29.07 ? 52  PHE A C    1 
ATOM   670  O O    . PHE A 1 54  ? 23.756  22.677 -19.923 1.00 19.90 ? 52  PHE A O    1 
ATOM   671  C CB   . PHE A 1 54  ? 26.293  20.891 -20.037 1.00 19.62 ? 52  PHE A CB   1 
ATOM   672  C CG   . PHE A 1 54  ? 27.602  20.316 -19.577 1.00 24.94 ? 52  PHE A CG   1 
ATOM   673  C CD1  . PHE A 1 54  ? 28.755  20.568 -20.274 1.00 23.53 ? 52  PHE A CD1  1 
ATOM   674  C CD2  . PHE A 1 54  ? 27.672  19.512 -18.458 1.00 22.83 ? 52  PHE A CD2  1 
ATOM   675  C CE1  . PHE A 1 54  ? 29.949  20.037 -19.866 1.00 21.72 ? 52  PHE A CE1  1 
ATOM   676  C CE2  . PHE A 1 54  ? 28.863  18.981 -18.042 1.00 20.15 ? 52  PHE A CE2  1 
ATOM   677  C CZ   . PHE A 1 54  ? 30.023  19.262 -18.752 1.00 21.30 ? 52  PHE A CZ   1 
ATOM   678  H H    . PHE A 1 54  ? 25.616  22.089 -17.895 1.00 25.66 ? 52  PHE A H    1 
ATOM   679  H HA   . PHE A 1 54  ? 26.904  22.836 -20.139 1.00 24.90 ? 52  PHE A HA   1 
ATOM   680  H HB2  . PHE A 1 54  ? 25.583  20.413 -19.579 1.00 23.61 ? 52  PHE A HB2  1 
ATOM   681  H HB3  . PHE A 1 54  ? 26.226  20.745 -20.994 1.00 23.61 ? 52  PHE A HB3  1 
ATOM   682  H HD1  . PHE A 1 54  ? 28.725  21.105 -21.033 1.00 28.30 ? 52  PHE A HD1  1 
ATOM   683  H HD2  . PHE A 1 54  ? 26.897  19.328 -17.978 1.00 27.46 ? 52  PHE A HD2  1 
ATOM   684  H HE1  . PHE A 1 54  ? 30.719  20.210 -20.357 1.00 26.12 ? 52  PHE A HE1  1 
ATOM   685  H HE2  . PHE A 1 54  ? 28.895  18.435 -17.290 1.00 24.24 ? 52  PHE A HE2  1 
ATOM   686  H HZ   . PHE A 1 54  ? 30.842  18.924 -18.469 1.00 25.62 ? 52  PHE A HZ   1 
ATOM   687  N N    . THR A 1 55  ? 25.061  23.535 -21.556 1.00 26.27 ? 53  THR A N    1 
ATOM   688  C CA   . THR A 1 55  ? 23.970  23.975 -22.409 1.00 25.76 ? 53  THR A CA   1 
ATOM   689  C C    . THR A 1 55  ? 24.290  23.652 -23.868 1.00 33.60 ? 53  THR A C    1 
ATOM   690  O O    . THR A 1 55  ? 23.377  23.687 -24.723 1.00 32.38 ? 53  THR A O    1 
ATOM   691  C CB   . THR A 1 55  ? 23.686  25.491 -22.295 1.00 28.39 ? 53  THR A CB   1 
ATOM   692  O OG1  . THR A 1 55  ? 24.907  26.202 -22.475 1.00 36.23 ? 53  THR A OG1  1 
ATOM   693  C CG2  . THR A 1 55  ? 23.117  25.824 -20.943 1.00 28.71 ? 53  THR A CG2  1 
ATOM   694  H H    . THR A 1 55  ? 25.837  23.742 -21.864 1.00 31.58 ? 53  THR A H    1 
ATOM   695  H HA   . THR A 1 55  ? 23.161  23.514 -22.138 1.00 30.98 ? 53  THR A HA   1 
ATOM   696  H HB   . THR A 1 55  ? 23.042  25.758 -22.969 1.00 34.13 ? 53  THR A HB   1 
ATOM   697  H HG1  . THR A 1 55  ? 25.378  26.145 -21.782 1.00 43.54 ? 53  THR A HG1  1 
ATOM   698  H HG21 . THR A 1 55  ? 22.837  26.752 -20.920 1.00 34.51 ? 53  THR A HG21 1 
ATOM   699  H HG22 . THR A 1 55  ? 22.350  25.259 -20.758 1.00 34.51 ? 53  THR A HG22 1 
ATOM   700  H HG23 . THR A 1 55  ? 23.787  25.680 -20.257 1.00 34.51 ? 53  THR A HG23 1 
ATOM   701  N N    . VAL A 1 60  ? 31.693  21.605 -23.218 1.00 33.10 ? 58  VAL A N    1 
ATOM   702  C CA   . VAL A 1 60  ? 32.970  21.404 -22.500 1.00 43.40 ? 58  VAL A CA   1 
ATOM   703  C C    . VAL A 1 60  ? 33.091  22.313 -21.273 1.00 39.95 ? 58  VAL A C    1 
ATOM   704  O O    . VAL A 1 60  ? 33.194  23.526 -21.379 1.00 38.31 ? 58  VAL A O    1 
ATOM   705  C CB   . VAL A 1 60  ? 34.186  21.629 -23.400 1.00 43.24 ? 58  VAL A CB   1 
ATOM   706  C CG1  . VAL A 1 60  ? 34.254  23.100 -23.867 1.00 45.47 ? 58  VAL A CG1  1 
ATOM   707  C CG2  . VAL A 1 60  ? 35.481  21.227 -22.682 1.00 44.00 ? 58  VAL A CG2  1 
ATOM   708  N N    . GLY A 1 61  ? 33.118  21.696 -20.104 1.00 27.10 ? 59  GLY A N    1 
ATOM   709  C CA   . GLY A 1 61  ? 32.837  22.418 -18.884 1.00 30.63 ? 59  GLY A CA   1 
ATOM   710  C C    . GLY A 1 61  ? 33.913  22.513 -17.825 1.00 21.96 ? 59  GLY A C    1 
ATOM   711  O O    . GLY A 1 61  ? 35.087  22.198 -18.052 1.00 23.91 ? 59  GLY A O    1 
ATOM   712  H H    . GLY A 1 61  ? 33.297  20.862 -19.994 1.00 32.58 ? 59  GLY A H    1 
ATOM   713  H HA2  . GLY A 1 61  ? 32.605  23.328 -19.127 1.00 36.82 ? 59  GLY A HA2  1 
ATOM   714  H HA3  . GLY A 1 61  ? 32.071  21.998 -18.463 1.00 36.82 ? 59  GLY A HA3  1 
ATOM   715  N N    . PHE A 1 62  ? 33.495  22.986 -16.654 1.00 20.35 ? 60  PHE A N    1 
ATOM   716  C CA   . PHE A 1 62  ? 34.349  23.084 -15.462 1.00 24.67 ? 60  PHE A CA   1 
ATOM   717  C C    . PHE A 1 62  ? 35.449  24.131 -15.639 1.00 29.68 ? 60  PHE A C    1 
ATOM   718  O O    . PHE A 1 62  ? 36.572  23.986 -15.141 1.00 25.72 ? 60  PHE A O    1 
ATOM   719  C CB   . PHE A 1 62  ? 34.933  21.724 -15.086 1.00 24.29 ? 60  PHE A CB   1 
ATOM   720  C CG   . PHE A 1 62  ? 33.895  20.709 -14.717 1.00 19.10 ? 60  PHE A CG   1 
ATOM   721  C CD1  . PHE A 1 62  ? 33.170  20.841 -13.554 1.00 18.59 ? 60  PHE A CD1  1 
ATOM   722  C CD2  . PHE A 1 62  ? 33.656  19.628 -15.540 1.00 22.67 ? 60  PHE A CD2  1 
ATOM   723  C CE1  . PHE A 1 62  ? 32.238  19.896 -13.206 1.00 18.91 ? 60  PHE A CE1  1 
ATOM   724  C CE2  . PHE A 1 62  ? 32.702  18.671 -15.200 1.00 23.74 ? 60  PHE A CE2  1 
ATOM   725  C CZ   . PHE A 1 62  ? 31.990  18.812 -14.043 1.00 20.69 ? 60  PHE A CZ   1 
ATOM   726  H H    . PHE A 1 62  ? 32.694  23.266 -16.514 1.00 24.48 ? 60  PHE A H    1 
ATOM   727  H HA   . PHE A 1 62  ? 33.801  23.383 -14.720 1.00 29.67 ? 60  PHE A HA   1 
ATOM   728  H HB2  . PHE A 1 62  ? 35.432  21.378 -15.843 1.00 29.21 ? 60  PHE A HB2  1 
ATOM   729  H HB3  . PHE A 1 62  ? 35.523  21.837 -14.324 1.00 29.21 ? 60  PHE A HB3  1 
ATOM   730  H HD1  . PHE A 1 62  ? 33.313  21.576 -13.001 1.00 22.37 ? 60  PHE A HD1  1 
ATOM   731  H HD2  . PHE A 1 62  ? 34.137  19.536 -16.331 1.00 27.27 ? 60  PHE A HD2  1 
ATOM   732  H HE1  . PHE A 1 62  ? 31.770  19.979 -12.406 1.00 22.75 ? 60  PHE A HE1  1 
ATOM   733  H HE2  . PHE A 1 62  ? 32.550  17.942 -15.758 1.00 28.54 ? 60  PHE A HE2  1 
ATOM   734  H HZ   . PHE A 1 62  ? 31.342  18.186 -13.815 1.00 24.89 ? 60  PHE A HZ   1 
ATOM   735  N N    . LEU A 1 63  ? 35.090  25.227 -16.303 1.00 31.61 ? 61  LEU A N    1 
ATOM   736  C CA   . LEU A 1 63  ? 36.069  26.290 -16.491 1.00 31.55 ? 61  LEU A CA   1 
ATOM   737  C C    . LEU A 1 63  ? 36.458  26.975 -15.183 1.00 26.33 ? 61  LEU A C    1 
ATOM   738  O O    . LEU A 1 63  ? 37.533  27.561 -15.121 1.00 30.37 ? 61  LEU A O    1 
ATOM   739  C CB   . LEU A 1 63  ? 35.533  27.306 -17.503 1.00 32.98 ? 61  LEU A CB   1 
ATOM   740  C CG   . LEU A 1 63  ? 35.418  26.684 -18.892 1.00 32.65 ? 61  LEU A CG   1 
ATOM   741  C CD1  . LEU A 1 63  ? 34.565  27.507 -19.794 1.00 35.88 ? 61  LEU A CD1  1 
ATOM   742  C CD2  . LEU A 1 63  ? 36.806  26.478 -19.532 1.00 42.72 ? 61  LEU A CD2  1 
ATOM   743  H H    . LEU A 1 63  ? 34.314  25.374 -16.643 1.00 38.00 ? 61  LEU A H    1 
ATOM   744  H HA   . LEU A 1 63  ? 36.884  25.910 -16.855 1.00 37.92 ? 61  LEU A HA   1 
ATOM   745  H HB2  . LEU A 1 63  ? 34.652  27.604 -17.224 1.00 39.64 ? 61  LEU A HB2  1 
ATOM   746  H HB3  . LEU A 1 63  ? 36.138  28.062 -17.552 1.00 39.64 ? 61  LEU A HB3  1 
ATOM   747  H HG   . LEU A 1 63  ? 34.997  25.817 -18.787 1.00 39.24 ? 61  LEU A HG   1 
ATOM   748  H HD11 . LEU A 1 63  ? 34.521  27.080 -20.664 1.00 43.11 ? 61  LEU A HD11 1 
ATOM   749  H HD12 . LEU A 1 63  ? 33.676  27.574 -19.413 1.00 43.11 ? 61  LEU A HD12 1 
ATOM   750  H HD13 . LEU A 1 63  ? 34.957  28.391 -19.879 1.00 43.11 ? 61  LEU A HD13 1 
ATOM   751  H HD21 . LEU A 1 63  ? 36.694  26.079 -20.409 1.00 51.33 ? 61  LEU A HD21 1 
ATOM   752  H HD22 . LEU A 1 63  ? 37.247  27.338 -19.614 1.00 51.33 ? 61  LEU A HD22 1 
ATOM   753  H HD23 . LEU A 1 63  ? 37.330  25.890 -18.966 1.00 51.33 ? 61  LEU A HD23 1 
ATOM   754  N N    . ASP A 1 64  ? 35.617  26.949 -14.140 1.00 27.18 ? 62  ASP A N    1 
ATOM   755  C CA   . ASP A 1 64  ? 36.020  27.542 -12.866 1.00 24.40 ? 62  ASP A CA   1 
ATOM   756  C C    . ASP A 1 64  ? 36.896  26.621 -12.024 1.00 31.48 ? 62  ASP A C    1 
ATOM   757  O O    . ASP A 1 64  ? 37.243  26.992 -10.887 1.00 30.04 ? 62  ASP A O    1 
ATOM   758  C CB   . ASP A 1 64  ? 34.799  27.941 -12.034 1.00 24.84 ? 62  ASP A CB   1 
ATOM   759  C CG   . ASP A 1 64  ? 33.976  28.987 -12.702 1.00 29.95 ? 62  ASP A CG   1 
ATOM   760  O OD1  . ASP A 1 64  ? 34.538  30.073 -12.978 1.00 33.84 ? 62  ASP A OD1  1 
ATOM   761  O OD2  . ASP A 1 64  ? 32.771  28.739 -12.924 1.00 33.24 ? 62  ASP A OD2  1 
ATOM   762  H H    . ASP A 1 64  ? 34.831  26.601 -14.149 1.00 32.68 ? 62  ASP A H    1 
ATOM   763  H HA   . ASP A 1 64  ? 36.521  28.346 -13.070 1.00 29.35 ? 62  ASP A HA   1 
ATOM   764  H HB2  . ASP A 1 64  ? 34.240  27.161 -11.895 1.00 29.87 ? 62  ASP A HB2  1 
ATOM   765  H HB3  . ASP A 1 64  ? 35.097  28.292 -11.180 1.00 29.87 ? 62  ASP A HB3  1 
ATOM   766  N N    . TYR A 1 65  ? 37.272  25.455 -12.552 1.00 26.78 ? 63  TYR A N    1 
ATOM   767  C CA   . TYR A 1 65  ? 37.874  24.394 -11.754 1.00 30.52 ? 63  TYR A CA   1 
ATOM   768  C C    . TYR A 1 65  ? 39.016  23.750 -12.523 1.00 26.55 ? 63  TYR A C    1 
ATOM   769  O O    . TYR A 1 65  ? 38.818  22.784 -13.266 1.00 30.28 ? 63  TYR A O    1 
ATOM   770  C CB   . TYR A 1 65  ? 36.812  23.362 -11.358 1.00 25.91 ? 63  TYR A CB   1 
ATOM   771  C CG   . TYR A 1 65  ? 35.760  23.909 -10.445 1.00 24.19 ? 63  TYR A CG   1 
ATOM   772  C CD1  . TYR A 1 65  ? 35.978  23.958 -9.099  1.00 25.69 ? 63  TYR A CD1  1 
ATOM   773  C CD2  . TYR A 1 65  ? 34.551  24.393 -10.946 1.00 20.83 ? 63  TYR A CD2  1 
ATOM   774  C CE1  . TYR A 1 65  ? 35.008  24.449 -8.242  1.00 31.87 ? 63  TYR A CE1  1 
ATOM   775  C CE2  . TYR A 1 65  ? 33.593  24.884 -10.122 1.00 23.91 ? 63  TYR A CE2  1 
ATOM   776  C CZ   . TYR A 1 65  ? 33.815  24.915 -8.767  1.00 27.08 ? 63  TYR A CZ   1 
ATOM   777  O OH   . TYR A 1 65  ? 32.876  25.435 -7.907  1.00 29.80 ? 63  TYR A OH   1 
ATOM   778  H H    . TYR A 1 65  ? 37.186  25.254 -13.384 1.00 32.20 ? 63  TYR A H    1 
ATOM   779  H HA   . TYR A 1 65  ? 38.262  24.775 -10.951 1.00 36.69 ? 63  TYR A HA   1 
ATOM   780  H HB2  . TYR A 1 65  ? 36.372  23.043 -12.161 1.00 31.16 ? 63  TYR A HB2  1 
ATOM   781  H HB3  . TYR A 1 65  ? 37.247  22.625 -10.901 1.00 31.16 ? 63  TYR A HB3  1 
ATOM   782  H HD1  . TYR A 1 65  ? 36.787  23.657 -8.754  1.00 30.89 ? 63  TYR A HD1  1 
ATOM   783  H HD2  . TYR A 1 65  ? 34.400  24.379 -11.863 1.00 25.06 ? 63  TYR A HD2  1 
ATOM   784  H HE1  . TYR A 1 65  ? 35.157  24.466 -7.324  1.00 38.31 ? 63  TYR A HE1  1 
ATOM   785  H HE2  . TYR A 1 65  ? 32.791  25.197 -10.472 1.00 28.75 ? 63  TYR A HE2  1 
ATOM   786  H HH   . TYR A 1 65  ? 33.145  25.369 -7.114  1.00 35.83 ? 63  TYR A HH   1 
ATOM   787  N N    . PRO A 1 66  ? 40.244  24.236 -12.334 1.00 32.38 ? 64  PRO A N    1 
ATOM   788  C CA   . PRO A 1 66  ? 41.373  23.692 -13.114 1.00 31.65 ? 64  PRO A CA   1 
ATOM   789  C C    . PRO A 1 66  ? 41.555  22.176 -13.001 1.00 32.11 ? 64  PRO A C    1 
ATOM   790  O O    . PRO A 1 66  ? 42.035  21.546 -13.955 1.00 32.44 ? 64  PRO A O    1 
ATOM   791  C CB   . PRO A 1 66  ? 42.589  24.445 -12.545 1.00 33.40 ? 64  PRO A CB   1 
ATOM   792  C CG   . PRO A 1 66  ? 42.079  25.236 -11.370 1.00 36.67 ? 64  PRO A CG   1 
ATOM   793  C CD   . PRO A 1 66  ? 40.632  25.430 -11.569 1.00 35.61 ? 64  PRO A CD   1 
ATOM   794  H HA   . PRO A 1 66  ? 41.251  23.925 -14.047 1.00 38.04 ? 64  PRO A HA   1 
ATOM   795  H HB2  . PRO A 1 66  ? 43.263  23.807 -12.262 1.00 40.15 ? 64  PRO A HB2  1 
ATOM   796  H HB3  . PRO A 1 66  ? 42.954  25.034 -13.223 1.00 40.15 ? 64  PRO A HB3  1 
ATOM   797  H HG2  . PRO A 1 66  ? 42.245  24.740 -10.552 1.00 44.07 ? 64  PRO A HG2  1 
ATOM   798  H HG3  . PRO A 1 66  ? 42.534  26.092 -11.337 1.00 44.07 ? 64  PRO A HG3  1 
ATOM   799  H HD2  . PRO A 1 66  ? 40.166  25.464 -10.719 1.00 42.80 ? 64  PRO A HD2  1 
ATOM   800  H HD3  . PRO A 1 66  ? 40.456  26.239 -12.075 1.00 42.80 ? 64  PRO A HD3  1 
ATOM   801  N N    . PHE A 1 67  ? 41.157  21.563 -11.890 1.00 33.01 ? 65  PHE A N    1 
ATOM   802  C CA   . PHE A 1 67  ? 41.382  20.127 -11.760 1.00 31.92 ? 65  PHE A CA   1 
ATOM   803  C C    . PHE A 1 67  ? 40.317  19.267 -12.437 1.00 31.79 ? 65  PHE A C    1 
ATOM   804  O O    . PHE A 1 67  ? 40.477  18.042 -12.499 1.00 29.77 ? 65  PHE A O    1 
ATOM   805  C CB   . PHE A 1 67  ? 41.439  19.733 -10.287 1.00 34.25 ? 65  PHE A CB   1 
ATOM   806  C CG   . PHE A 1 67  ? 42.667  20.211 -9.568  1.00 38.85 ? 65  PHE A CG   1 
ATOM   807  C CD1  . PHE A 1 67  ? 43.901  20.237 -10.211 1.00 40.60 ? 65  PHE A CD1  1 
ATOM   808  C CD2  . PHE A 1 67  ? 42.591  20.626 -8.246  1.00 41.22 ? 65  PHE A CD2  1 
ATOM   809  C CE1  . PHE A 1 67  ? 45.044  20.689 -9.571  1.00 42.07 ? 65  PHE A CE1  1 
ATOM   810  C CE2  . PHE A 1 67  ? 43.735  21.065 -7.584  1.00 39.80 ? 65  PHE A CE2  1 
ATOM   811  C CZ   . PHE A 1 67  ? 44.976  21.091 -8.262  1.00 36.97 ? 65  PHE A CZ   1 
ATOM   812  H H    . PHE A 1 67  ? 40.770  21.942 -11.223 1.00 39.67 ? 65  PHE A H    1 
ATOM   813  H HA   . PHE A 1 67  ? 42.236  19.933 -12.176 1.00 38.36 ? 65  PHE A HA   1 
ATOM   814  H HB2  . PHE A 1 67  ? 40.669  20.110 -9.835  1.00 41.16 ? 65  PHE A HB2  1 
ATOM   815  H HB3  . PHE A 1 67  ? 41.420  18.765 -10.224 1.00 41.16 ? 65  PHE A HB3  1 
ATOM   816  H HD1  . PHE A 1 67  ? 43.959  19.944 -11.092 1.00 48.79 ? 65  PHE A HD1  1 
ATOM   817  H HD2  . PHE A 1 67  ? 41.774  20.612 -7.802  1.00 49.52 ? 65  PHE A HD2  1 
ATOM   818  H HE1  . PHE A 1 67  ? 45.853  20.720 -10.027 1.00 50.54 ? 65  PHE A HE1  1 
ATOM   819  H HE2  . PHE A 1 67  ? 43.682  21.341 -6.698  1.00 47.82 ? 65  PHE A HE2  1 
ATOM   820  H HZ   . PHE A 1 67  ? 45.743  21.379 -7.822  1.00 44.43 ? 65  PHE A HZ   1 
ATOM   821  N N    . CYS A 1 68  ? 39.240  19.856 -12.935 1.00 28.00 ? 66  CYS A N    1 
ATOM   822  C CA   . CYS A 1 68  ? 38.146  19.109 -13.530 1.00 23.79 ? 66  CYS A CA   1 
ATOM   823  C C    . CYS A 1 68  ? 37.941  19.573 -14.963 1.00 21.97 ? 66  CYS A C    1 
ATOM   824  O O    . CYS A 1 68  ? 38.044  20.769 -15.263 1.00 24.40 ? 66  CYS A O    1 
ATOM   825  C CB   . CYS A 1 68  ? 36.844  19.342 -12.750 1.00 20.52 ? 66  CYS A CB   1 
ATOM   826  S SG   . CYS A 1 68  ? 36.749  18.614 -11.114 1.00 25.87 ? 66  CYS A SG   1 
ATOM   827  H H    . CYS A 1 68  ? 39.119  20.708 -12.940 1.00 33.67 ? 66  CYS A H    1 
ATOM   828  H HA   . CYS A 1 68  ? 38.358  18.163 -13.526 1.00 28.61 ? 66  CYS A HA   1 
ATOM   829  H HB2  . CYS A 1 68  ? 36.725  20.299 -12.643 1.00 24.69 ? 66  CYS A HB2  1 
ATOM   830  H HB3  . CYS A 1 68  ? 36.113  18.972 -13.269 1.00 24.69 ? 66  CYS A HB3  1 
ATOM   831  N N    . SER A 1 69  ? 37.635  18.633 -15.835 1.00 19.56 ? 67  SER A N    1 
ATOM   832  C CA   . SER A 1 69  ? 37.159  18.919 -17.174 1.00 23.23 ? 67  SER A CA   1 
ATOM   833  C C    . SER A 1 69  ? 36.067  17.918 -17.529 1.00 24.00 ? 67  SER A C    1 
ATOM   834  O O    . SER A 1 69  ? 35.874  16.904 -16.855 1.00 23.47 ? 67  SER A O    1 
ATOM   835  C CB   . SER A 1 69  ? 38.291  18.865 -18.209 1.00 31.04 ? 67  SER A CB   1 
ATOM   836  O OG   . SER A 1 69  ? 39.082  17.694 -18.039 1.00 37.22 ? 67  SER A OG   1 
ATOM   837  H H    . SER A 1 69  ? 37.697  17.791 -15.670 1.00 23.53 ? 67  SER A H    1 
ATOM   838  H HA   . SER A 1 69  ? 36.781  19.812 -17.190 1.00 27.93 ? 67  SER A HA   1 
ATOM   839  H HB2  . SER A 1 69  ? 37.904  18.857 -19.098 1.00 37.31 ? 67  SER A HB2  1 
ATOM   840  H HB3  . SER A 1 69  ? 38.856  19.645 -18.099 1.00 37.31 ? 67  SER A HB3  1 
ATOM   841  H HG   . SER A 1 69  ? 39.136  17.275 -18.766 1.00 44.72 ? 67  SER A HG   1 
ATOM   842  N N    . GLY A 1 70  ? 35.314  18.215 -18.579 1.00 24.58 ? 68  GLY A N    1 
ATOM   843  C CA   . GLY A 1 70  ? 34.262  17.307 -18.962 1.00 26.78 ? 68  GLY A CA   1 
ATOM   844  C C    . GLY A 1 70  ? 33.543  17.739 -20.211 1.00 24.67 ? 68  GLY A C    1 
ATOM   845  O O    . GLY A 1 70  ? 33.483  18.925 -20.554 1.00 22.85 ? 68  GLY A O    1 
ATOM   846  H H    . GLY A 1 70  ? 35.395  18.918 -19.068 1.00 29.55 ? 68  GLY A H    1 
ATOM   847  H HA2  . GLY A 1 70  ? 34.641  16.428 -19.118 1.00 32.20 ? 68  GLY A HA2  1 
ATOM   848  H HA3  . GLY A 1 70  ? 33.614  17.249 -18.243 1.00 32.20 ? 68  GLY A HA3  1 
ATOM   849  N N    . THR A 1 71  ? 33.007  16.751 -20.903 1.00 23.30 ? 69  THR A N    1 
ATOM   850  C CA   . THR A 1 71  ? 32.214  16.962 -22.099 1.00 25.24 ? 69  THR A CA   1 
ATOM   851  C C    . THR A 1 71  ? 30.881  16.252 -21.909 1.00 26.72 ? 69  THR A C    1 
ATOM   852  O O    . THR A 1 71  ? 30.821  15.190 -21.274 1.00 27.16 ? 69  THR A O    1 
ATOM   853  C CB   . THR A 1 71  ? 32.893  16.380 -23.344 1.00 26.97 ? 69  THR A CB   1 
ATOM   854  O OG1  . THR A 1 71  ? 33.381  15.072 -23.031 1.00 36.16 ? 69  THR A OG1  1 
ATOM   855  C CG2  . THR A 1 71  ? 34.020  17.261 -23.739 1.00 32.55 ? 69  THR A CG2  1 
ATOM   856  H H    . THR A 1 71  ? 33.091  15.921 -20.692 1.00 28.02 ? 69  THR A H    1 
ATOM   857  H HA   . THR A 1 71  ? 32.078  17.912 -22.239 1.00 30.35 ? 69  THR A HA   1 
ATOM   858  H HB   . THR A 1 71  ? 32.271  16.318 -24.086 1.00 32.42 ? 69  THR A HB   1 
ATOM   859  H HG1  . THR A 1 71  ? 34.048  15.129 -22.523 1.00 43.45 ? 69  THR A HG1  1 
ATOM   860  H HG21 . THR A 1 71  ? 34.414  16.943 -24.566 1.00 39.12 ? 69  THR A HG21 1 
ATOM   861  H HG22 . THR A 1 71  ? 33.702  18.168 -23.870 1.00 39.12 ? 69  THR A HG22 1 
ATOM   862  H HG23 . THR A 1 71  ? 34.699  17.262 -23.046 1.00 39.12 ? 69  THR A HG23 1 
ATOM   863  N N    . PHE A 1 72  ? 29.817  16.812 -22.487 1.00 23.77 ? 70  PHE A N    1 
ATOM   864  C CA   . PHE A 1 72  ? 28.463  16.304 -22.267 1.00 23.72 ? 70  PHE A CA   1 
ATOM   865  C C    . PHE A 1 72  ? 27.738  16.032 -23.569 1.00 29.15 ? 70  PHE A C    1 
ATOM   866  O O    . PHE A 1 72  ? 27.500  16.962 -24.348 1.00 30.05 ? 70  PHE A O    1 
ATOM   867  C CB   . PHE A 1 72  ? 27.625  17.292 -21.486 1.00 27.19 ? 70  PHE A CB   1 
ATOM   868  C CG   . PHE A 1 72  ? 26.231  16.803 -21.195 1.00 25.21 ? 70  PHE A CG   1 
ATOM   869  C CD1  . PHE A 1 72  ? 26.007  15.773 -20.299 1.00 25.24 ? 70  PHE A CD1  1 
ATOM   870  C CD2  . PHE A 1 72  ? 25.145  17.328 -21.892 1.00 31.17 ? 70  PHE A CD2  1 
ATOM   871  C CE1  . PHE A 1 72  ? 24.698  15.335 -20.033 1.00 24.55 ? 70  PHE A CE1  1 
ATOM   872  C CE2  . PHE A 1 72  ? 23.857  16.888 -21.643 1.00 28.43 ? 70  PHE A CE2  1 
ATOM   873  C CZ   . PHE A 1 72  ? 23.638  15.893 -20.721 1.00 22.68 ? 70  PHE A CZ   1 
ATOM   874  H H    . PHE A 1 72  ? 29.855  17.491 -23.013 1.00 28.59 ? 70  PHE A H    1 
ATOM   875  H HA   . PHE A 1 72  ? 28.566  15.465 -21.791 1.00 28.52 ? 70  PHE A HA   1 
ATOM   876  H HB2  . PHE A 1 72  ? 28.061  17.468 -20.637 1.00 32.69 ? 70  PHE A HB2  1 
ATOM   877  H HB3  . PHE A 1 72  ? 27.552  18.112 -21.998 1.00 32.69 ? 70  PHE A HB3  1 
ATOM   878  H HD1  . PHE A 1 72  ? 26.726  15.368 -19.870 1.00 30.35 ? 70  PHE A HD1  1 
ATOM   879  H HD2  . PHE A 1 72  ? 25.288  17.985 -22.535 1.00 37.47 ? 70  PHE A HD2  1 
ATOM   880  H HE1  . PHE A 1 72  ? 24.547  14.673 -19.398 1.00 29.52 ? 70  PHE A HE1  1 
ATOM   881  H HE2  . PHE A 1 72  ? 23.140  17.265 -22.099 1.00 34.18 ? 70  PHE A HE2  1 
ATOM   882  H HZ   . PHE A 1 72  ? 22.772  15.594 -20.559 1.00 27.28 ? 70  PHE A HZ   1 
ATOM   883  N N    . ASN A 1 73  ? 27.277  14.797 -23.737 1.00 24.83 ? 71  ASN A N    1 
ATOM   884  C CA   . ASN A 1 73  ? 26.589  14.329 -24.931 1.00 36.67 ? 71  ASN A CA   1 
ATOM   885  C C    . ASN A 1 73  ? 25.435  13.430 -24.532 1.00 35.68 ? 71  ASN A C    1 
ATOM   886  O O    . ASN A 1 73  ? 25.615  12.488 -23.754 1.00 30.50 ? 71  ASN A O    1 
ATOM   887  C CB   . ASN A 1 73  ? 27.520  13.534 -25.851 1.00 35.42 ? 71  ASN A CB   1 
ATOM   888  C CG   . ASN A 1 73  ? 27.164  13.677 -27.312 1.00 40.53 ? 71  ASN A CG   1 
ATOM   889  O OD1  . ASN A 1 73  ? 25.992  13.733 -27.666 1.00 53.31 ? 71  ASN A OD1  1 
ATOM   890  N ND2  . ASN A 1 73  ? 28.169  13.739 -28.173 1.00 44.88 ? 71  ASN A ND2  1 
ATOM   891  H H    . ASN A 1 73  ? 27.357  14.181 -23.142 1.00 29.85 ? 71  ASN A H    1 
ATOM   892  H HA   . ASN A 1 73  ? 26.249  15.102 -25.407 1.00 44.06 ? 71  ASN A HA   1 
ATOM   893  H HB2  . ASN A 1 73  ? 28.428  13.852 -25.731 1.00 42.57 ? 71  ASN A HB2  1 
ATOM   894  H HB3  . ASN A 1 73  ? 27.465  12.593 -25.620 1.00 42.57 ? 71  ASN A HB3  1 
ATOM   895  H HD21 . ASN A 1 73  ? 28.980  13.698 -27.890 1.00 53.92 ? 71  ASN A HD21 1 
ATOM   896  H HD22 . ASN A 1 73  ? 28.011  13.821 -29.014 1.00 53.92 ? 71  ASN A HD22 1 
ATOM   897  N N    . GLU A 1 74  ? 24.280  13.683 -25.136 1.00 31.13 ? 72  GLU A N    1 
ATOM   898  C CA   . GLU A 1 74  ? 23.105  12.867 -24.899 1.00 31.94 ? 72  GLU A CA   1 
ATOM   899  C C    . GLU A 1 74  ? 22.641  13.047 -23.457 1.00 34.23 ? 72  GLU A C    1 
ATOM   900  O O    . GLU A 1 74  ? 22.045  14.079 -23.102 1.00 37.42 ? 72  GLU A O    1 
ATOM   901  C CB   . GLU A 1 74  ? 23.426  11.408 -25.233 1.00 34.02 ? 72  GLU A CB   1 
ATOM   902  C CG   . GLU A 1 74  ? 23.771  11.166 -26.693 1.00 40.76 ? 72  GLU A CG   1 
ATOM   903  C CD   . GLU A 1 74  ? 22.862  10.125 -27.326 1.00 42.23 ? 72  GLU A CD   1 
ATOM   904  O OE1  . GLU A 1 74  ? 21.708  9.952  -26.875 1.00 44.97 ? 72  GLU A OE1  1 
ATOM   905  O OE2  . GLU A 1 74  ? 23.285  9.492  -28.307 1.00 39.00 ? 72  GLU A OE2  1 
ATOM   906  N N    . SER A 1 75  ? 22.961  12.068 -22.613 1.00 25.84 ? 73  SER A N    1 
ATOM   907  C CA   . SER A 1 75  ? 22.668  12.123 -21.187 1.00 23.08 ? 73  SER A CA   1 
ATOM   908  C C    . SER A 1 75  ? 23.868  11.663 -20.386 1.00 23.52 ? 73  SER A C    1 
ATOM   909  O O    . SER A 1 75  ? 23.722  11.143 -19.281 1.00 23.57 ? 73  SER A O    1 
ATOM   910  C CB   . SER A 1 75  ? 21.431  11.296 -20.835 1.00 21.45 ? 73  SER A CB   1 
ATOM   911  O OG   . SER A 1 75  ? 20.342  11.857 -21.508 1.00 28.19 ? 73  SER A OG   1 
ATOM   912  H H    . SER A 1 75  ? 23.360  11.344 -22.850 1.00 31.07 ? 73  SER A H    1 
ATOM   913  H HA   . SER A 1 75  ? 22.473  13.041 -20.944 1.00 27.76 ? 73  SER A HA   1 
ATOM   914  H HB2  . SER A 1 75  ? 21.557  10.378 -21.122 1.00 25.80 ? 73  SER A HB2  1 
ATOM   915  H HB3  . SER A 1 75  ? 21.277  11.327 -19.878 1.00 25.80 ? 73  SER A HB3  1 
ATOM   916  H HG   . SER A 1 75  ? 19.658  11.383 -21.392 1.00 33.89 ? 73  SER A HG   1 
ATOM   917  N N    . ARG A 1 76  ? 25.065  11.869 -20.912 1.00 21.27 ? 74  ARG A N    1 
ATOM   918  C CA   . ARG A 1 76  ? 26.268  11.327 -20.301 1.00 21.97 ? 74  ARG A CA   1 
ATOM   919  C C    . ARG A 1 76  ? 27.372  12.374 -20.314 1.00 24.97 ? 74  ARG A C    1 
ATOM   920  O O    . ARG A 1 76  ? 27.644  12.995 -21.347 1.00 24.75 ? 74  ARG A O    1 
ATOM   921  C CB   . ARG A 1 76  ? 26.711  10.070 -21.035 1.00 25.22 ? 74  ARG A CB   1 
ATOM   922  C CG   . ARG A 1 76  ? 28.115  9.631  -20.724 1.00 25.35 ? 74  ARG A CG   1 
ATOM   923  C CD   . ARG A 1 76  ? 28.484  8.445  -21.593 1.00 32.43 ? 74  ARG A CD   1 
ATOM   924  N NE   . ARG A 1 76  ? 29.728  7.816  -21.174 1.00 40.63 ? 74  ARG A NE   1 
ATOM   925  C CZ   . ARG A 1 76  ? 30.084  6.582  -21.505 1.00 46.73 ? 74  ARG A CZ   1 
ATOM   926  N NH1  . ARG A 1 76  ? 29.299  5.814  -22.241 1.00 47.44 ? 74  ARG A NH1  1 
ATOM   927  N NH2  . ARG A 1 76  ? 31.278  6.126  -21.129 1.00 42.04 ? 74  ARG A NH2  1 
ATOM   928  H H    . ARG A 1 76  ? 25.207  12.323 -21.629 1.00 25.58 ? 74  ARG A H    1 
ATOM   929  H HA   . ARG A 1 76  ? 26.095  11.107 -19.372 1.00 26.42 ? 74  ARG A HA   1 
ATOM   930  H HB2  . ARG A 1 76  ? 26.116  9.343  -20.791 1.00 30.33 ? 74  ARG A HB2  1 
ATOM   931  H HB3  . ARG A 1 76  ? 26.660  10.234 -21.990 1.00 30.33 ? 74  ARG A HB3  1 
ATOM   932  H HG2  . ARG A 1 76  ? 28.734  10.356 -20.906 1.00 30.48 ? 74  ARG A HG2  1 
ATOM   933  H HG3  . ARG A 1 76  ? 28.178  9.367  -19.793 1.00 30.48 ? 74  ARG A HG3  1 
ATOM   934  H HD2  . ARG A 1 76  ? 27.778  7.782  -21.542 1.00 38.97 ? 74  ARG A HD2  1 
ATOM   935  H HD3  . ARG A 1 76  ? 28.592  8.744  -22.510 1.00 38.97 ? 74  ARG A HD3  1 
ATOM   936  H HE   . ARG A 1 76  ? 30.265  8.273  -20.681 1.00 48.81 ? 74  ARG A HE   1 
ATOM   937  H HH11 . ARG A 1 76  ? 28.541  6.111  -22.516 1.00 56.98 ? 74  ARG A HH11 1 
ATOM   938  H HH12 . ARG A 1 76  ? 29.548  5.016  -22.446 1.00 56.98 ? 74  ARG A HH12 1 
ATOM   939  H HH21 . ARG A 1 76  ? 31.808  6.630  -20.677 1.00 50.51 ? 74  ARG A HH21 1 
ATOM   940  H HH22 . ARG A 1 76  ? 31.518  5.328  -21.339 1.00 50.51 ? 74  ARG A HH22 1 
ATOM   941  N N    . VAL A 1 77  ? 27.983  12.598 -19.159 1.00 22.96 ? 75  VAL A N    1 
ATOM   942  C CA   . VAL A 1 77  ? 29.147  13.464 -19.046 1.00 22.46 ? 75  VAL A CA   1 
ATOM   943  C C    . VAL A 1 77  ? 30.378  12.584 -18.906 1.00 22.46 ? 75  VAL A C    1 
ATOM   944  O O    . VAL A 1 77  ? 30.403  11.645 -18.092 1.00 18.54 ? 75  VAL A O    1 
ATOM   945  C CB   . VAL A 1 77  ? 29.015  14.441 -17.863 1.00 22.84 ? 75  VAL A CB   1 
ATOM   946  C CG1  . VAL A 1 77  ? 28.911  13.700 -16.589 1.00 24.40 ? 75  VAL A CG1  1 
ATOM   947  C CG2  . VAL A 1 77  ? 30.216  15.388 -17.808 1.00 22.81 ? 75  VAL A CG2  1 
ATOM   948  H H    . VAL A 1 77  ? 27.735  12.251 -18.411 1.00 27.61 ? 75  VAL A H    1 
ATOM   949  H HA   . VAL A 1 77  ? 29.238  13.990 -19.856 1.00 27.02 ? 75  VAL A HA   1 
ATOM   950  H HB   . VAL A 1 77  ? 28.210  14.967 -17.988 1.00 27.46 ? 75  VAL A HB   1 
ATOM   951  H HG11 . VAL A 1 77  ? 28.712  14.325 -15.875 1.00 29.34 ? 75  VAL A HG11 1 
ATOM   952  H HG12 . VAL A 1 77  ? 28.201  13.044 -16.662 1.00 29.34 ? 75  VAL A HG12 1 
ATOM   953  H HG13 . VAL A 1 77  ? 29.755  13.255 -16.412 1.00 29.34 ? 75  VAL A HG13 1 
ATOM   954  H HG21 . VAL A 1 77  ? 30.070  16.044 -17.109 1.00 27.44 ? 75  VAL A HG21 1 
ATOM   955  H HG22 . VAL A 1 77  ? 31.016  14.873 -17.617 1.00 27.44 ? 75  VAL A HG22 1 
ATOM   956  H HG23 . VAL A 1 77  ? 30.307  15.833 -18.665 1.00 27.44 ? 75  VAL A HG23 1 
ATOM   957  N N    . ASN A 1 78  ? 31.406  12.901 -19.683 1.00 22.98 ? 76  ASN A N    1 
ATOM   958  C CA   . ASN A 1 78  ? 32.702  12.239 -19.548 1.00 24.11 ? 76  ASN A CA   1 
ATOM   959  C C    . ASN A 1 78  ? 33.557  13.130 -18.666 1.00 24.78 ? 76  ASN A C    1 
ATOM   960  O O    . ASN A 1 78  ? 33.991  14.199 -19.094 1.00 26.60 ? 76  ASN A O    1 
ATOM   961  C CB   . ASN A 1 78  ? 33.357  11.991 -20.897 1.00 31.10 ? 76  ASN A CB   1 
ATOM   962  C CG   . ASN A 1 78  ? 32.915  10.680 -21.512 1.00 40.88 ? 76  ASN A CG   1 
ATOM   963  O OD1  . ASN A 1 78  ? 31.724  10.324 -21.489 1.00 34.10 ? 76  ASN A OD1  1 
ATOM   964  N ND2  . ASN A 1 78  ? 33.882  9.922  -22.023 1.00 55.09 ? 76  ASN A ND2  1 
ATOM   965  H H    . ASN A 1 78  ? 31.380  13.500 -20.300 1.00 27.63 ? 76  ASN A H    1 
ATOM   966  H HA   . ASN A 1 78  ? 32.581  11.374 -19.125 1.00 29.00 ? 76  ASN A HA   1 
ATOM   967  H HB2  . ASN A 1 78  ? 33.115  12.708 -21.504 1.00 37.38 ? 76  ASN A HB2  1 
ATOM   968  H HB3  . ASN A 1 78  ? 34.319  11.963 -20.783 1.00 37.38 ? 76  ASN A HB3  1 
ATOM   969  H HD21 . ASN A 1 78  ? 34.699  10.188 -21.991 1.00 66.17 ? 76  ASN A HD21 1 
ATOM   970  H HD22 . ASN A 1 78  ? 33.690  9.167  -22.386 1.00 66.17 ? 76  ASN A HD22 1 
ATOM   971  N N    . LEU A 1 79  ? 33.699  12.741 -17.401 1.00 21.26 ? 77  LEU A N    1 
ATOM   972  C CA   . LEU A 1 79  ? 34.416  13.531 -16.418 1.00 22.41 ? 77  LEU A CA   1 
ATOM   973  C C    . LEU A 1 79  ? 35.896  13.177 -16.473 1.00 25.28 ? 77  LEU A C    1 
ATOM   974  O O    . LEU A 1 79  ? 36.251  12.019 -16.712 1.00 22.49 ? 77  LEU A O    1 
ATOM   975  C CB   . LEU A 1 79  ? 33.895  13.284 -14.992 1.00 21.74 ? 77  LEU A CB   1 
ATOM   976  C CG   . LEU A 1 79  ? 32.449  13.680 -14.705 1.00 23.24 ? 77  LEU A CG   1 
ATOM   977  C CD1  . LEU A 1 79  ? 31.862  13.105 -13.388 1.00 27.92 ? 77  LEU A CD1  1 
ATOM   978  C CD2  . LEU A 1 79  ? 32.362  15.196 -14.702 1.00 26.44 ? 77  LEU A CD2  1 
ATOM   979  H H    . LEU A 1 79  ? 33.380  12.006 -17.086 1.00 25.57 ? 77  LEU A H    1 
ATOM   980  H HA   . LEU A 1 79  ? 34.289  14.471 -16.618 1.00 26.95 ? 77  LEU A HA   1 
ATOM   981  H HB2  . LEU A 1 79  ? 33.971  12.335 -14.806 1.00 26.15 ? 77  LEU A HB2  1 
ATOM   982  H HB3  . LEU A 1 79  ? 34.453  13.788 -14.379 1.00 26.15 ? 77  LEU A HB3  1 
ATOM   983  H HG   . LEU A 1 79  ? 31.898  13.292 -15.403 1.00 27.94 ? 77  LEU A HG   1 
ATOM   984  H HD11 . LEU A 1 79  ? 30.952  13.423 -13.283 1.00 33.56 ? 77  LEU A HD11 1 
ATOM   985  H HD12 . LEU A 1 79  ? 31.871  12.136 -13.435 1.00 33.56 ? 77  LEU A HD12 1 
ATOM   986  H HD13 . LEU A 1 79  ? 32.406  13.405 -12.643 1.00 33.56 ? 77  LEU A HD13 1 
ATOM   987  H HD21 . LEU A 1 79  ? 31.465  15.460 -14.444 1.00 31.79 ? 77  LEU A HD21 1 
ATOM   988  H HD22 . LEU A 1 79  ? 33.005  15.548 -14.067 1.00 31.79 ? 77  LEU A HD22 1 
ATOM   989  H HD23 . LEU A 1 79  ? 32.560  15.526 -15.592 1.00 31.79 ? 77  LEU A HD23 1 
ATOM   990  N N    . THR A 1 80  ? 36.750  14.183 -16.232 1.00 24.35 ? 78  THR A N    1 
ATOM   991  C CA   . THR A 1 80  ? 38.171  13.983 -15.986 1.00 21.30 ? 78  THR A CA   1 
ATOM   992  C C    . THR A 1 80  ? 38.547  14.799 -14.760 1.00 22.77 ? 78  THR A C    1 
ATOM   993  O O    . THR A 1 80  ? 38.292  16.018 -14.706 1.00 24.19 ? 78  THR A O    1 
ATOM   994  C CB   . THR A 1 80  ? 39.003  14.389 -17.206 1.00 26.76 ? 78  THR A CB   1 
ATOM   995  O OG1  . THR A 1 80  ? 38.743  13.453 -18.258 1.00 30.11 ? 78  THR A OG1  1 
ATOM   996  C CG2  . THR A 1 80  ? 40.482  14.345 -16.880 1.00 28.77 ? 78  THR A CG2  1 
ATOM   997  H H    . THR A 1 80  ? 36.516  15.010 -16.207 1.00 29.28 ? 78  THR A H    1 
ATOM   998  H HA   . THR A 1 80  ? 38.365  13.049 -15.805 1.00 25.62 ? 78  THR A HA   1 
ATOM   999  H HB   . THR A 1 80  ? 38.775  15.292 -17.479 1.00 32.17 ? 78  THR A HB   1 
ATOM   1000 H HG1  . THR A 1 80  ? 38.727  12.671 -17.949 1.00 36.20 ? 78  THR A HG1  1 
ATOM   1001 H HG21 . THR A 1 80  ? 40.995  14.176 -17.686 1.00 34.59 ? 78  THR A HG21 1 
ATOM   1002 H HG22 . THR A 1 80  ? 40.764  15.191 -16.499 1.00 34.59 ? 78  THR A HG22 1 
ATOM   1003 H HG23 . THR A 1 80  ? 40.660  13.637 -16.240 1.00 34.59 ? 78  THR A HG23 1 
ATOM   1004 N N    . ILE A 1 81  ? 39.156  14.145 -13.776 1.00 21.58 ? 79  ILE A N    1 
ATOM   1005 C CA   . ILE A 1 81  ? 39.684  14.809 -12.594 1.00 22.34 ? 79  ILE A CA   1 
ATOM   1006 C C    . ILE A 1 81  ? 41.186  14.596 -12.572 1.00 26.88 ? 79  ILE A C    1 
ATOM   1007 O O    . ILE A 1 81  ? 41.660  13.456 -12.648 1.00 26.54 ? 79  ILE A O    1 
ATOM   1008 C CB   . ILE A 1 81  ? 39.073  14.286 -11.290 1.00 24.00 ? 79  ILE A CB   1 
ATOM   1009 C CG1  . ILE A 1 81  ? 37.556  14.417 -11.330 1.00 25.49 ? 79  ILE A CG1  1 
ATOM   1010 C CG2  . ILE A 1 81  ? 39.654  15.062 -10.119 1.00 24.73 ? 79  ILE A CG2  1 
ATOM   1011 C CD1  . ILE A 1 81  ? 36.842  13.627 -10.238 1.00 26.58 ? 79  ILE A CD1  1 
ATOM   1012 H H    . ILE A 1 81  ? 39.277  13.294 -13.773 1.00 25.96 ? 79  ILE A H    1 
ATOM   1013 H HA   . ILE A 1 81  ? 39.479  15.754 -12.664 1.00 26.86 ? 79  ILE A HA   1 
ATOM   1014 H HB   . ILE A 1 81  ? 39.290  13.347 -11.186 1.00 28.86 ? 79  ILE A HB   1 
ATOM   1015 H HG12 . ILE A 1 81  ? 37.320  15.352 -11.221 1.00 30.64 ? 79  ILE A HG12 1 
ATOM   1016 H HG13 . ILE A 1 81  ? 37.237  14.092 -12.187 1.00 30.64 ? 79  ILE A HG13 1 
ATOM   1017 H HG21 . ILE A 1 81  ? 39.036  15.018 -9.373  1.00 29.74 ? 79  ILE A HG21 1 
ATOM   1018 H HG22 . ILE A 1 81  ? 40.504  14.667 -9.869  1.00 29.74 ? 79  ILE A HG22 1 
ATOM   1019 H HG23 . ILE A 1 81  ? 39.785  15.985 -10.386 1.00 29.74 ? 79  ILE A HG23 1 
ATOM   1020 H HD11 . ILE A 1 81  ? 35.890  13.619 -10.424 1.00 31.96 ? 79  ILE A HD11 1 
ATOM   1021 H HD12 . ILE A 1 81  ? 37.185  12.719 -10.230 1.00 31.96 ? 79  ILE A HD12 1 
ATOM   1022 H HD13 . ILE A 1 81  ? 37.009  14.051 -9.381  1.00 31.96 ? 79  ILE A HD13 1 
ATOM   1023 N N    . GLN A 1 82  ? 41.927  15.690 -12.522 1.00 30.39 ? 80  GLN A N    1 
ATOM   1024 C CA   . GLN A 1 82  ? 43.377  15.666 -12.605 1.00 30.63 ? 80  GLN A CA   1 
ATOM   1025 C C    . GLN A 1 82  ? 43.959  16.249 -11.319 1.00 28.56 ? 80  GLN A C    1 
ATOM   1026 O O    . GLN A 1 82  ? 43.239  16.695 -10.421 1.00 28.20 ? 80  GLN A O    1 
ATOM   1027 C CB   . GLN A 1 82  ? 43.844  16.422 -13.847 1.00 29.42 ? 80  GLN A CB   1 
ATOM   1028 H H    . GLN A 1 82  ? 41.602  16.482 -12.439 1.00 36.53 ? 80  GLN A H    1 
ATOM   1029 H HA   . GLN A 1 82  ? 43.696  14.753 -12.679 1.00 36.81 ? 80  GLN A HA   1 
ATOM   1030 N N    . GLY A 1 83  ? 45.284  16.190 -11.216 1.00 32.02 ? 81  GLY A N    1 
ATOM   1031 C CA   . GLY A 1 83  ? 45.974  16.674 -10.042 1.00 31.30 ? 81  GLY A CA   1 
ATOM   1032 C C    . GLY A 1 83  ? 45.840  15.789 -8.829  1.00 27.06 ? 81  GLY A C    1 
ATOM   1033 O O    . GLY A 1 83  ? 46.170  16.229 -7.724  1.00 29.96 ? 81  GLY A O    1 
ATOM   1034 H H    . GLY A 1 83  ? 45.804  15.870 -11.821 1.00 38.49 ? 81  GLY A H    1 
ATOM   1035 H HA2  . GLY A 1 83  ? 46.919  16.756 -10.247 1.00 37.62 ? 81  GLY A HA2  1 
ATOM   1036 H HA3  . GLY A 1 83  ? 45.624  17.549 -9.812  1.00 37.62 ? 81  GLY A HA3  1 
ATOM   1037 N N    . LEU A 1 84  ? 45.391  14.547 -9.007  1.00 29.32 ? 82  LEU A N    1 
ATOM   1038 C CA   . LEU A 1 84  ? 45.129  13.656 -7.894  1.00 28.68 ? 82  LEU A CA   1 
ATOM   1039 C C    . LEU A 1 84  ? 46.434  13.078 -7.348  1.00 34.89 ? 82  LEU A C    1 
ATOM   1040 O O    . LEU A 1 84  ? 47.386  12.803 -8.088  1.00 32.37 ? 82  LEU A O    1 
ATOM   1041 C CB   . LEU A 1 84  ? 44.201  12.514 -8.320  1.00 32.64 ? 82  LEU A CB   1 
ATOM   1042 C CG   . LEU A 1 84  ? 42.839  12.953 -8.876  1.00 30.50 ? 82  LEU A CG   1 
ATOM   1043 C CD1  . LEU A 1 84  ? 42.096  11.814 -9.560  1.00 30.65 ? 82  LEU A CD1  1 
ATOM   1044 C CD2  . LEU A 1 84  ? 42.026  13.545 -7.743  1.00 31.32 ? 82  LEU A CD2  1 
ATOM   1045 H H    . LEU A 1 84  ? 45.230  14.197 -9.776  1.00 35.24 ? 82  LEU A H    1 
ATOM   1046 H HA   . LEU A 1 84  ? 44.693  14.154 -7.185  1.00 34.47 ? 82  LEU A HA   1 
ATOM   1047 H HB2  . LEU A 1 84  ? 44.646  12.000 -9.013  1.00 39.23 ? 82  LEU A HB2  1 
ATOM   1048 H HB3  . LEU A 1 84  ? 44.033  11.952 -7.547  1.00 39.23 ? 82  LEU A HB3  1 
ATOM   1049 H HG   . LEU A 1 84  ? 42.973  13.623 -9.564  1.00 36.66 ? 82  LEU A HG   1 
ATOM   1050 H HD11 . LEU A 1 84  ? 41.254  12.149 -9.908  1.00 36.85 ? 82  LEU A HD11 1 
ATOM   1051 H HD12 . LEU A 1 84  ? 42.641  11.473 -10.287 1.00 36.85 ? 82  LEU A HD12 1 
ATOM   1052 H HD13 . LEU A 1 84  ? 41.929  11.111 -8.913  1.00 36.85 ? 82  LEU A HD13 1 
ATOM   1053 H HD21 . LEU A 1 84  ? 41.085  13.502 -7.974  1.00 37.64 ? 82  LEU A HD21 1 
ATOM   1054 H HD22 . LEU A 1 84  ? 42.192  13.034 -6.935  1.00 37.64 ? 82  LEU A HD22 1 
ATOM   1055 H HD23 . LEU A 1 84  ? 42.293  14.468 -7.611  1.00 37.64 ? 82  LEU A HD23 1 
ATOM   1056 N N    . ARG A 1 85  ? 46.452  12.896 -6.034  1.00 32.69 ? 83  ARG A N    1 
ATOM   1057 C CA   . ARG A 1 85  ? 47.540  12.268 -5.300  1.00 40.81 ? 83  ARG A CA   1 
ATOM   1058 C C    . ARG A 1 85  ? 46.966  11.150 -4.441  1.00 40.29 ? 83  ARG A C    1 
ATOM   1059 O O    . ARG A 1 85  ? 45.751  10.995 -4.332  1.00 31.41 ? 83  ARG A O    1 
ATOM   1060 C CB   . ARG A 1 85  ? 48.264  13.289 -4.422  1.00 38.53 ? 83  ARG A CB   1 
ATOM   1061 C CG   . ARG A 1 85  ? 48.189  14.697 -4.964  1.00 42.59 ? 83  ARG A CG   1 
ATOM   1062 C CD   . ARG A 1 85  ? 48.819  15.742 -4.022  1.00 43.82 ? 83  ARG A CD   1 
ATOM   1063 N NE   . ARG A 1 85  ? 47.891  16.078 -2.943  1.00 50.43 ? 83  ARG A NE   1 
ATOM   1064 C CZ   . ARG A 1 85  ? 46.672  16.579 -3.136  1.00 54.03 ? 83  ARG A CZ   1 
ATOM   1065 N NH1  . ARG A 1 85  ? 46.188  16.788 -4.355  1.00 47.13 ? 83  ARG A NH1  1 
ATOM   1066 N NH2  . ARG A 1 85  ? 45.889  16.804 -2.086  1.00 47.88 ? 83  ARG A NH2  1 
ATOM   1067 N N    . ALA A 1 86  ? 47.844  10.356 -3.819  1.00 35.38 ? 84  ALA A N    1 
ATOM   1068 C CA   . ALA A 1 86  ? 47.361  9.178  -3.107  1.00 36.56 ? 84  ALA A CA   1 
ATOM   1069 C C    . ALA A 1 86  ? 46.378  9.551  -2.008  1.00 31.80 ? 84  ALA A C    1 
ATOM   1070 O O    . ALA A 1 86  ? 45.416  8.815  -1.757  1.00 30.96 ? 84  ALA A O    1 
ATOM   1071 C CB   . ALA A 1 86  ? 48.534  8.388  -2.531  1.00 37.43 ? 84  ALA A CB   1 
ATOM   1072 H H    . ALA A 1 86  ? 48.695  10.475 -3.797  1.00 42.52 ? 84  ALA A H    1 
ATOM   1073 H HA   . ALA A 1 86  ? 46.898  8.608  -3.740  1.00 43.93 ? 84  ALA A HA   1 
ATOM   1074 H HB1  . ALA A 1 86  ? 48.195  7.585  -2.105  1.00 44.98 ? 84  ALA A HB1  1 
ATOM   1075 H HB2  . ALA A 1 86  ? 49.139  8.151  -3.251  1.00 44.98 ? 84  ALA A HB2  1 
ATOM   1076 H HB3  . ALA A 1 86  ? 48.995  8.939  -1.879  1.00 44.98 ? 84  ALA A HB3  1 
ATOM   1077 N N    . VAL A 1 87  ? 46.584  10.701 -1.359  1.00 34.77 ? 85  VAL A N    1 
ATOM   1078 C CA   . VAL A 1 87  ? 45.690  11.112 -0.290  1.00 31.52 ? 85  VAL A CA   1 
ATOM   1079 C C    . VAL A 1 87  ? 44.310  11.463 -0.822  1.00 28.50 ? 85  VAL A C    1 
ATOM   1080 O O    . VAL A 1 87  ? 43.352  11.496 -0.046  1.00 31.44 ? 85  VAL A O    1 
ATOM   1081 C CB   . VAL A 1 87  ? 46.235  12.321 0.490   1.00 35.91 ? 85  VAL A CB   1 
ATOM   1082 C CG1  . VAL A 1 87  ? 47.481  11.939 1.287   1.00 42.93 ? 85  VAL A CG1  1 
ATOM   1083 C CG2  . VAL A 1 87  ? 46.505  13.481 -0.453  1.00 36.11 ? 85  VAL A CG2  1 
ATOM   1084 H H    . VAL A 1 87  ? 47.227  11.249 -1.520  1.00 41.79 ? 85  VAL A H    1 
ATOM   1085 H HA   . VAL A 1 87  ? 45.628  10.359 0.319   1.00 37.89 ? 85  VAL A HA   1 
ATOM   1086 H HB   . VAL A 1 87  ? 45.566  12.612 1.129   1.00 43.15 ? 85  VAL A HB   1 
ATOM   1087 H HG11 . VAL A 1 87  ? 47.798  12.718 1.769   1.00 51.57 ? 85  VAL A HG11 1 
ATOM   1088 H HG12 . VAL A 1 87  ? 47.252  11.233 1.912   1.00 51.57 ? 85  VAL A HG12 1 
ATOM   1089 H HG13 . VAL A 1 87  ? 48.165  11.628 0.673   1.00 51.57 ? 85  VAL A HG13 1 
ATOM   1090 H HG21 . VAL A 1 87  ? 46.832  14.236 0.061   1.00 43.39 ? 85  VAL A HG21 1 
ATOM   1091 H HG22 . VAL A 1 87  ? 47.172  13.211 -1.104  1.00 43.39 ? 85  VAL A HG22 1 
ATOM   1092 H HG23 . VAL A 1 87  ? 45.680  13.720 -0.904  1.00 43.39 ? 85  VAL A HG23 1 
ATOM   1093 N N    . ASP A 1 88  ? 44.201  11.732 -2.125  1.00 32.16 ? 86  ASP A N    1 
ATOM   1094 C CA   . ASP A 1 88  ? 42.921  12.045 -2.761  1.00 30.30 ? 86  ASP A CA   1 
ATOM   1095 C C    . ASP A 1 88  ? 42.072  10.804 -3.032  1.00 33.56 ? 86  ASP A C    1 
ATOM   1096 O O    . ASP A 1 88  ? 40.907  10.936 -3.435  1.00 27.49 ? 86  ASP A O    1 
ATOM   1097 C CB   . ASP A 1 88  ? 43.175  12.786 -4.072  1.00 29.95 ? 86  ASP A CB   1 
ATOM   1098 C CG   . ASP A 1 88  ? 43.933  14.080 -3.865  1.00 32.13 ? 86  ASP A CG   1 
ATOM   1099 O OD1  . ASP A 1 88  ? 43.712  14.764 -2.836  1.00 33.76 ? 86  ASP A OD1  1 
ATOM   1100 O OD2  . ASP A 1 88  ? 44.773  14.399 -4.728  1.00 34.57 ? 86  ASP A OD2  1 
ATOM   1101 H H    . ASP A 1 88  ? 44.865  11.739 -2.671  1.00 38.66 ? 86  ASP A H    1 
ATOM   1102 H HA   . ASP A 1 88  ? 42.410  12.625 -2.176  1.00 36.43 ? 86  ASP A HA   1 
ATOM   1103 H HB2  . ASP A 1 88  ? 43.699  12.221 -4.660  1.00 36.00 ? 86  ASP A HB2  1 
ATOM   1104 H HB3  . ASP A 1 88  ? 42.324  12.999 -4.486  1.00 36.00 ? 86  ASP A HB3  1 
ATOM   1105 N N    . THR A 1 89  ? 42.630  9.609  -2.839  1.00 27.82 ? 87  THR A N    1 
ATOM   1106 C CA   . THR A 1 89  ? 41.855  8.376  -2.927  1.00 26.45 ? 87  THR A CA   1 
ATOM   1107 C C    . THR A 1 89  ? 40.586  8.533  -2.110  1.00 26.34 ? 87  THR A C    1 
ATOM   1108 O O    . THR A 1 89  ? 40.630  8.996  -0.966  1.00 27.95 ? 87  THR A O    1 
ATOM   1109 C CB   . THR A 1 89  ? 42.692  7.195  -2.400  1.00 27.13 ? 87  THR A CB   1 
ATOM   1110 O OG1  . THR A 1 89  ? 43.810  6.984  -3.265  1.00 28.34 ? 87  THR A OG1  1 
ATOM   1111 C CG2  . THR A 1 89  ? 41.880  5.935  -2.337  1.00 27.94 ? 87  THR A CG2  1 
ATOM   1112 H H    . THR A 1 89  ? 43.461  9.485  -2.655  1.00 33.45 ? 87  THR A H    1 
ATOM   1113 H HA   . THR A 1 89  ? 41.622  8.185  -3.848  1.00 31.80 ? 87  THR A HA   1 
ATOM   1114 H HB   . THR A 1 89  ? 42.998  7.400  -1.503  1.00 32.61 ? 87  THR A HB   1 
ATOM   1115 H HG1  . THR A 1 89  ? 44.139  7.722  -3.496  1.00 34.07 ? 87  THR A HG1  1 
ATOM   1116 H HG21 . THR A 1 89  ? 42.458  5.162  -2.434  1.00 33.59 ? 87  THR A HG21 1 
ATOM   1117 H HG22 . THR A 1 89  ? 41.420  5.879  -1.485  1.00 33.59 ? 87  THR A HG22 1 
ATOM   1118 H HG23 . THR A 1 89  ? 41.222  5.928  -3.050  1.00 33.59 ? 87  THR A HG23 1 
ATOM   1119 N N    . GLY A 1 90  ? 39.451  8.181  -2.703  1.00 27.33 ? 88  GLY A N    1 
ATOM   1120 C CA   . GLY A 1 90  ? 38.200  8.315  -1.989  1.00 26.17 ? 88  GLY A CA   1 
ATOM   1121 C C    . GLY A 1 90  ? 37.006  8.162  -2.916  1.00 22.99 ? 88  GLY A C    1 
ATOM   1122 O O    . GLY A 1 90  ? 37.148  7.805  -4.091  1.00 19.40 ? 88  GLY A O    1 
ATOM   1123 H H    . GLY A 1 90  ? 39.384  7.868  -3.502  1.00 32.86 ? 88  GLY A H    1 
ATOM   1124 H HA2  . GLY A 1 90  ? 38.145  7.634  -1.300  1.00 31.46 ? 88  GLY A HA2  1 
ATOM   1125 H HA3  . GLY A 1 90  ? 38.157  9.190  -1.572  1.00 31.46 ? 88  GLY A HA3  1 
ATOM   1126 N N    . LEU A 1 91  ? 35.823  8.431  -2.357  1.00 19.67 ? 89  LEU A N    1 
ATOM   1127 C CA   . LEU A 1 91  ? 34.573  8.232  -3.082  1.00 21.74 ? 89  LEU A CA   1 
ATOM   1128 C C    . LEU A 1 91  ? 34.084  9.574  -3.636  1.00 17.77 ? 89  LEU A C    1 
ATOM   1129 O O    . LEU A 1 91  ? 33.883  10.531 -2.887  1.00 22.74 ? 89  LEU A O    1 
ATOM   1130 C CB   . LEU A 1 91  ? 33.537  7.597  -2.167  1.00 25.07 ? 89  LEU A CB   1 
ATOM   1131 C CG   . LEU A 1 91  ? 32.229  7.162  -2.825  1.00 21.01 ? 89  LEU A CG   1 
ATOM   1132 C CD1  . LEU A 1 91  ? 32.364  5.972  -3.765  1.00 22.97 ? 89  LEU A CD1  1 
ATOM   1133 C CD2  . LEU A 1 91  ? 31.198  6.897  -1.765  1.00 24.88 ? 89  LEU A CD2  1 
ATOM   1134 H H    . LEU A 1 91  ? 35.722  8.731  -1.558  1.00 23.66 ? 89  LEU A H    1 
ATOM   1135 H HA   . LEU A 1 91  ? 34.717  7.643  -3.839  1.00 26.15 ? 89  LEU A HA   1 
ATOM   1136 H HB2  . LEU A 1 91  ? 33.932  6.807  -1.766  1.00 30.15 ? 89  LEU A HB2  1 
ATOM   1137 H HB3  . LEU A 1 91  ? 33.310  8.241  -1.477  1.00 30.15 ? 89  LEU A HB3  1 
ATOM   1138 H HG   . LEU A 1 91  ? 31.939  7.891  -3.394  1.00 25.27 ? 89  LEU A HG   1 
ATOM   1139 H HD11 . LEU A 1 91  ? 31.478  5.666  -4.016  1.00 27.62 ? 89  LEU A HD11 1 
ATOM   1140 H HD12 . LEU A 1 91  ? 32.855  6.248  -4.555  1.00 27.62 ? 89  LEU A HD12 1 
ATOM   1141 H HD13 . LEU A 1 91  ? 32.842  5.262  -3.309  1.00 27.62 ? 89  LEU A HD13 1 
ATOM   1142 H HD21 . LEU A 1 91  ? 30.368  6.632  -2.191  1.00 29.92 ? 89  LEU A HD21 1 
ATOM   1143 H HD22 . LEU A 1 91  ? 31.514  6.186  -1.186  1.00 29.92 ? 89  LEU A HD22 1 
ATOM   1144 H HD23 . LEU A 1 91  ? 31.060  7.707  -1.249  1.00 29.92 ? 89  LEU A HD23 1 
ATOM   1145 N N    . TYR A 1 92  ? 33.873  9.625  -4.938  1.00 20.78 ? 90  TYR A N    1 
ATOM   1146 C CA   . TYR A 1 92  ? 33.509  10.850 -5.624  1.00 22.14 ? 90  TYR A CA   1 
ATOM   1147 C C    . TYR A 1 92  ? 32.121  10.668 -6.212  1.00 16.67 ? 90  TYR A C    1 
ATOM   1148 O O    . TYR A 1 92  ? 31.910  9.821  -7.090  1.00 17.77 ? 90  TYR A O    1 
ATOM   1149 C CB   . TYR A 1 92  ? 34.521  11.174 -6.708  1.00 16.66 ? 90  TYR A CB   1 
ATOM   1150 C CG   . TYR A 1 92  ? 35.872  11.610 -6.176  1.00 18.57 ? 90  TYR A CG   1 
ATOM   1151 C CD1  . TYR A 1 92  ? 36.750  10.696 -5.601  1.00 21.50 ? 90  TYR A CD1  1 
ATOM   1152 C CD2  . TYR A 1 92  ? 36.265  12.939 -6.246  1.00 21.73 ? 90  TYR A CD2  1 
ATOM   1153 C CE1  . TYR A 1 92  ? 37.970  11.096 -5.135  1.00 22.04 ? 90  TYR A CE1  1 
ATOM   1154 C CE2  . TYR A 1 92  ? 37.483  13.343 -5.770  1.00 21.96 ? 90  TYR A CE2  1 
ATOM   1155 C CZ   . TYR A 1 92  ? 38.329  12.425 -5.223  1.00 24.42 ? 90  TYR A CZ   1 
ATOM   1156 O OH   . TYR A 1 92  ? 39.560  12.862 -4.769  1.00 27.68 ? 90  TYR A OH   1 
ATOM   1157 H H    . TYR A 1 92  ? 33.936  8.945  -5.460  1.00 25.00 ? 90  TYR A H    1 
ATOM   1158 H HA   . TYR A 1 92  ? 33.484  11.585 -4.991  1.00 26.63 ? 90  TYR A HA   1 
ATOM   1159 H HB2  . TYR A 1 92  ? 34.658  10.383 -7.252  1.00 20.05 ? 90  TYR A HB2  1 
ATOM   1160 H HB3  . TYR A 1 92  ? 34.171  11.896 -7.254  1.00 20.05 ? 90  TYR A HB3  1 
ATOM   1161 H HD1  . TYR A 1 92  ? 36.503  9.801  -5.534  1.00 25.86 ? 90  TYR A HD1  1 
ATOM   1162 H HD2  . TYR A 1 92  ? 35.691  13.566 -6.623  1.00 26.14 ? 90  TYR A HD2  1 
ATOM   1163 H HE1  . TYR A 1 92  ? 38.554  10.477 -4.761  1.00 26.51 ? 90  TYR A HE1  1 
ATOM   1164 H HE2  . TYR A 1 92  ? 37.732  14.238 -5.819  1.00 26.42 ? 90  TYR A HE2  1 
ATOM   1165 H HH   . TYR A 1 92  ? 39.968  12.231 -4.393  1.00 33.27 ? 90  TYR A HH   1 
ATOM   1166 N N    . LEU A 1 93  ? 31.176  11.435 -5.680  1.00 17.07 ? 91  LEU A N    1 
ATOM   1167 C CA   . LEU A 1 93  ? 29.801  11.362 -6.097  1.00 15.79 ? 91  LEU A CA   1 
ATOM   1168 C C    . LEU A 1 93  ? 29.545  12.285 -7.281  1.00 17.16 ? 91  LEU A C    1 
ATOM   1169 O O    . LEU A 1 93  ? 29.973  13.442 -7.297  1.00 17.61 ? 91  LEU A O    1 
ATOM   1170 C CB   . LEU A 1 93  ? 28.869  11.736 -4.952  1.00 16.13 ? 91  LEU A CB   1 
ATOM   1171 C CG   . LEU A 1 93  ? 29.100  11.113 -3.596  1.00 22.92 ? 91  LEU A CG   1 
ATOM   1172 C CD1  . LEU A 1 93  ? 28.268  11.848 -2.582  1.00 25.84 ? 91  LEU A CD1  1 
ATOM   1173 C CD2  . LEU A 1 93  ? 28.730  9.665  -3.721  1.00 26.27 ? 91  LEU A CD2  1 
ATOM   1174 H H    . LEU A 1 93  ? 31.320  12.017 -5.063  1.00 20.54 ? 91  LEU A H    1 
ATOM   1175 H HA   . LEU A 1 93  ? 29.607  10.452 -6.371  1.00 19.01 ? 91  LEU A HA   1 
ATOM   1176 H HB2  . LEU A 1 93  ? 28.929  12.696 -4.828  1.00 19.42 ? 91  LEU A HB2  1 
ATOM   1177 H HB3  . LEU A 1 93  ? 27.968  11.492 -5.218  1.00 19.42 ? 91  LEU A HB3  1 
ATOM   1178 H HG   . LEU A 1 93  ? 30.019  11.170 -3.291  1.00 27.57 ? 91  LEU A HG   1 
ATOM   1179 H HD11 . LEU A 1 93  ? 28.465  11.499 -1.698  1.00 31.07 ? 91  LEU A HD11 1 
ATOM   1180 H HD12 . LEU A 1 93  ? 28.486  12.793 -2.620  1.00 31.07 ? 91  LEU A HD12 1 
ATOM   1181 H HD13 . LEU A 1 93  ? 27.330  11.717 -2.788  1.00 31.07 ? 91  LEU A HD13 1 
ATOM   1182 H HD21 . LEU A 1 93  ? 28.953  9.210  -2.894  1.00 31.58 ? 91  LEU A HD21 1 
ATOM   1183 H HD22 . LEU A 1 93  ? 27.778  9.596  -3.891  1.00 31.58 ? 91  LEU A HD22 1 
ATOM   1184 H HD23 . LEU A 1 93  ? 29.227  9.275  -4.458  1.00 31.58 ? 91  LEU A HD23 1 
ATOM   1185 N N    . CYS A 1 94  ? 28.765  11.778 -8.236  1.00 16.19 ? 92  CYS A N    1 
ATOM   1186 C CA   . CYS A 1 94  ? 28.268  12.572 -9.344  1.00 16.79 ? 92  CYS A CA   1 
ATOM   1187 C C    . CYS A 1 94  ? 26.843  13.029 -9.036  1.00 13.98 ? 92  CYS A C    1 
ATOM   1188 O O    . CYS A 1 94  ? 25.972  12.206 -8.745  1.00 15.48 ? 92  CYS A O    1 
ATOM   1189 C CB   . CYS A 1 94  ? 28.286  11.773 -10.642 1.00 16.93 ? 92  CYS A CB   1 
ATOM   1190 S SG   . CYS A 1 94  ? 27.732  12.742 -11.995 1.00 25.91 ? 92  CYS A SG   1 
ATOM   1191 H H    . CYS A 1 94  ? 28.508  10.957 -8.259  1.00 19.49 ? 92  CYS A H    1 
ATOM   1192 H HA   . CYS A 1 94  ? 28.831  13.353 -9.459  1.00 20.20 ? 92  CYS A HA   1 
ATOM   1193 H HB2  . CYS A 1 94  ? 29.192  11.479 -10.826 1.00 20.38 ? 92  CYS A HB2  1 
ATOM   1194 H HB3  . CYS A 1 94  ? 27.699  11.005 -10.555 1.00 20.38 ? 92  CYS A HB3  1 
ATOM   1195 N N    . LYS A 1 95  ? 26.610  14.338 -9.081  1.00 11.43 ? 93  LYS A N    1 
ATOM   1196 C CA   . LYS A 1 95  ? 25.276  14.911 -8.952  1.00 10.84 ? 93  LYS A CA   1 
ATOM   1197 C C    . LYS A 1 95  ? 24.887  15.509 -10.287 1.00 12.94 ? 93  LYS A C    1 
ATOM   1198 O O    . LYS A 1 95  ? 25.655  16.303 -10.858 1.00 12.96 ? 93  LYS A O    1 
ATOM   1199 C CB   . LYS A 1 95  ? 25.242  16.014 -7.895  1.00 12.02 ? 93  LYS A CB   1 
ATOM   1200 C CG   . LYS A 1 95  ? 23.910  16.833 -7.705  1.00 11.34 ? 93  LYS A CG   1 
ATOM   1201 C CD   . LYS A 1 95  ? 24.191  17.890 -6.652  1.00 12.39 ? 93  LYS A CD   1 
ATOM   1202 C CE   . LYS A 1 95  ? 23.175  18.953 -6.579  1.00 14.36 ? 93  LYS A CE   1 
ATOM   1203 N NZ   . LYS A 1 95  ? 23.418  19.867 -5.475  1.00 12.01 ? 93  LYS A NZ   1 
ATOM   1204 H H    . LYS A 1 95  ? 27.227  14.928 -9.187  1.00 13.77 ? 93  LYS A H    1 
ATOM   1205 H HA   . LYS A 1 95  ? 24.649  14.216 -8.698  1.00 13.06 ? 93  LYS A HA   1 
ATOM   1206 H HB2  . LYS A 1 95  ? 25.439  15.604 -7.038  1.00 14.49 ? 93  LYS A HB2  1 
ATOM   1207 H HB3  . LYS A 1 95  ? 25.932  16.658 -8.121  1.00 14.49 ? 93  LYS A HB3  1 
ATOM   1208 H HG2  . LYS A 1 95  ? 23.654  17.263 -8.536  1.00 13.67 ? 93  LYS A HG2  1 
ATOM   1209 H HG3  . LYS A 1 95  ? 23.196  16.253 -7.399  1.00 13.67 ? 93  LYS A HG3  1 
ATOM   1210 H HD2  . LYS A 1 95  ? 24.230  17.461 -5.783  1.00 14.93 ? 93  LYS A HD2  1 
ATOM   1211 H HD3  . LYS A 1 95  ? 25.042  18.310 -6.853  1.00 14.93 ? 93  LYS A HD3  1 
ATOM   1212 H HE2  . LYS A 1 95  ? 23.188  19.464 -7.403  1.00 17.29 ? 93  LYS A HE2  1 
ATOM   1213 H HE3  . LYS A 1 95  ? 22.301  18.551 -6.451  1.00 17.29 ? 93  LYS A HE3  1 
ATOM   1214 H HZ1  . LYS A 1 95  ? 22.983  20.631 -5.611  1.00 14.48 ? 93  LYS A HZ1  1 
ATOM   1215 H HZ2  . LYS A 1 95  ? 23.135  19.505 -4.713  1.00 14.48 ? 93  LYS A HZ2  1 
ATOM   1216 H HZ3  . LYS A 1 95  ? 24.289  20.038 -5.408  1.00 14.48 ? 93  LYS A HZ3  1 
ATOM   1217 N N    . VAL A 1 96  ? 23.676  15.202 -10.743 1.00 12.30 ? 94  VAL A N    1 
ATOM   1218 C CA   . VAL A 1 96  ? 23.149  15.718 -11.994 1.00 13.41 ? 94  VAL A CA   1 
ATOM   1219 C C    . VAL A 1 96  ? 21.862  16.454 -11.702 1.00 10.66 ? 94  VAL A C    1 
ATOM   1220 O O    . VAL A 1 96  ? 20.972  15.898 -11.058 1.00 12.39 ? 94  VAL A O    1 
ATOM   1221 C CB   . VAL A 1 96  ? 22.884  14.587 -13.002 1.00 11.50 ? 94  VAL A CB   1 
ATOM   1222 C CG1  . VAL A 1 96  ? 22.221  15.107 -14.290 1.00 15.35 ? 94  VAL A CG1  1 
ATOM   1223 C CG2  . VAL A 1 96  ? 24.178  13.852 -13.364 1.00 14.87 ? 94  VAL A CG2  1 
ATOM   1224 H H    . VAL A 1 96  ? 23.129  14.683 -10.331 1.00 14.82 ? 94  VAL A H    1 
ATOM   1225 H HA   . VAL A 1 96  ? 23.789  16.340 -12.374 1.00 16.15 ? 94  VAL A HA   1 
ATOM   1226 H HB   . VAL A 1 96  ? 22.275  13.966 -12.574 1.00 13.86 ? 94  VAL A HB   1 
ATOM   1227 H HG11 . VAL A 1 96  ? 22.374  14.469 -15.004 1.00 18.48 ? 94  VAL A HG11 1 
ATOM   1228 H HG12 . VAL A 1 96  ? 21.268  15.209 -14.136 1.00 18.48 ? 94  VAL A HG12 1 
ATOM   1229 H HG13 . VAL A 1 96  ? 22.611  15.964 -14.523 1.00 18.48 ? 94  VAL A HG13 1 
ATOM   1230 H HG21 . VAL A 1 96  ? 24.012  13.277 -14.128 1.00 17.90 ? 94  VAL A HG21 1 
ATOM   1231 H HG22 . VAL A 1 96  ? 24.861  14.505 -13.584 1.00 17.90 ? 94  VAL A HG22 1 
ATOM   1232 H HG23 . VAL A 1 96  ? 24.461  13.319 -12.605 1.00 17.90 ? 94  VAL A HG23 1 
ATOM   1233 N N    . GLU A 1 97  ? 21.746  17.673 -12.224 1.00 8.81  ? 95  GLU A N    1 
ATOM   1234 C CA   . GLU A 1 97  ? 20.521  18.448 -12.171 1.00 10.37 ? 95  GLU A CA   1 
ATOM   1235 C C    . GLU A 1 97  ? 20.038  18.812 -13.574 1.00 10.99 ? 95  GLU A C    1 
ATOM   1236 O O    . GLU A 1 97  ? 20.811  19.345 -14.377 1.00 12.59 ? 95  GLU A O    1 
ATOM   1237 C CB   . GLU A 1 97  ? 20.750  19.736 -11.371 1.00 10.60 ? 95  GLU A CB   1 
ATOM   1238 C CG   . GLU A 1 97  ? 21.071  19.494 -9.886  1.00 11.68 ? 95  GLU A CG   1 
ATOM   1239 C CD   . GLU A 1 97  ? 21.649  20.718 -9.252  1.00 13.37 ? 95  GLU A CD   1 
ATOM   1240 O OE1  . GLU A 1 97  ? 22.814  21.031 -9.562  1.00 11.93 ? 95  GLU A OE1  1 
ATOM   1241 O OE2  . GLU A 1 97  ? 20.932  21.390 -8.473  1.00 12.90 ? 95  GLU A OE2  1 
ATOM   1242 H H    . GLU A 1 97  ? 22.388  18.081 -12.625 1.00 10.64 ? 95  GLU A H    1 
ATOM   1243 H HA   . GLU A 1 97  ? 19.831  17.907 -11.757 1.00 12.51 ? 95  GLU A HA   1 
ATOM   1244 H HB2  . GLU A 1 97  ? 21.498  20.216 -11.761 1.00 12.79 ? 95  GLU A HB2  1 
ATOM   1245 H HB3  . GLU A 1 97  ? 19.947  20.278 -11.416 1.00 12.79 ? 95  GLU A HB3  1 
ATOM   1246 H HG2  . GLU A 1 97  ? 20.256  19.260 -9.415  1.00 14.08 ? 95  GLU A HG2  1 
ATOM   1247 H HG3  . GLU A 1 97  ? 21.717  18.775 -9.809  1.00 14.08 ? 95  GLU A HG3  1 
ATOM   1248 N N    . LEU A 1 98  ? 18.731  18.647 -13.818 1.00 10.42 ? 96  LEU A N    1 
ATOM   1249 C CA   . LEU A 1 98  ? 18.067  19.130 -15.033 1.00 10.60 ? 96  LEU A CA   1 
ATOM   1250 C C    . LEU A 1 98  ? 17.410  20.435 -14.599 1.00 12.83 ? 96  LEU A C    1 
ATOM   1251 O O    . LEU A 1 98  ? 16.383  20.421 -13.919 1.00 13.02 ? 96  LEU A O    1 
ATOM   1252 C CB   . LEU A 1 98  ? 17.094  18.074 -15.544 1.00 12.30 ? 96  LEU A CB   1 
ATOM   1253 C CG   . LEU A 1 98  ? 17.694  16.636 -15.644 1.00 13.95 ? 96  LEU A CG   1 
ATOM   1254 C CD1  . LEU A 1 98  ? 16.712  15.712 -16.347 1.00 14.30 ? 96  LEU A CD1  1 
ATOM   1255 C CD2  . LEU A 1 98  ? 19.011  16.596 -16.328 1.00 13.34 ? 96  LEU A CD2  1 
ATOM   1256 H H    . LEU A 1 98  ? 18.195  18.246 -13.279 1.00 12.56 ? 96  LEU A H    1 
ATOM   1257 H HA   . LEU A 1 98  ? 18.675  19.310 -15.767 1.00 12.78 ? 96  LEU A HA   1 
ATOM   1258 H HB2  . LEU A 1 98  ? 16.336  18.034 -14.940 1.00 14.82 ? 96  LEU A HB2  1 
ATOM   1259 H HB3  . LEU A 1 98  ? 16.797  18.330 -16.431 1.00 14.82 ? 96  LEU A HB3  1 
ATOM   1260 H HG   . LEU A 1 98  ? 17.850  16.324 -14.738 1.00 16.80 ? 96  LEU A HG   1 
ATOM   1261 H HD11 . LEU A 1 98  ? 17.118  14.837 -16.447 1.00 17.22 ? 96  LEU A HD11 1 
ATOM   1262 H HD12 . LEU A 1 98  ? 15.905  15.644 -15.814 1.00 17.22 ? 96  LEU A HD12 1 
ATOM   1263 H HD13 . LEU A 1 98  ? 16.502  16.081 -17.220 1.00 17.22 ? 96  LEU A HD13 1 
ATOM   1264 H HD21 . LEU A 1 98  ? 19.175  15.695 -16.647 1.00 16.07 ? 96  LEU A HD21 1 
ATOM   1265 H HD22 . LEU A 1 98  ? 18.998  17.214 -17.075 1.00 16.07 ? 96  LEU A HD22 1 
ATOM   1266 H HD23 . LEU A 1 98  ? 19.702  16.854 -15.698 1.00 16.07 ? 96  LEU A HD23 1 
ATOM   1267 N N    . MET A 1 99  ? 18.020  21.576 -14.962 1.00 10.72 ? 97  MET A N    1 
ATOM   1268 C CA   . MET A 1 99  ? 17.681  22.809 -14.278 1.00 12.85 ? 97  MET A CA   1 
ATOM   1269 C C    . MET A 1 99  ? 16.467  23.524 -14.815 1.00 14.05 ? 97  MET A C    1 
ATOM   1270 O O    . MET A 1 99  ? 15.769  24.150 -14.012 1.00 14.07 ? 97  MET A O    1 
ATOM   1271 C CB   . MET A 1 99  ? 18.813  23.808 -14.286 1.00 12.57 ? 97  MET A CB   1 
ATOM   1272 C CG   . MET A 1 99  ? 20.119  23.284 -13.667 1.00 13.88 ? 97  MET A CG   1 
ATOM   1273 S SD   . MET A 1 99  ? 19.981  23.099 -11.896 1.00 13.37 ? 97  MET A SD   1 
ATOM   1274 C CE   . MET A 1 99  ? 19.716  24.769 -11.386 1.00 15.58 ? 97  MET A CE   1 
ATOM   1275 H H    . MET A 1 99  ? 18.611  21.647 -15.582 1.00 12.92 ? 97  MET A H    1 
ATOM   1276 H HA   . MET A 1 99  ? 17.517  22.525 -13.365 1.00 15.48 ? 97  MET A HA   1 
ATOM   1277 H HB2  . MET A 1 99  ? 19.001  24.056 -15.205 1.00 15.14 ? 97  MET A HB2  1 
ATOM   1278 H HB3  . MET A 1 99  ? 18.540  24.590 -13.781 1.00 15.14 ? 97  MET A HB3  1 
ATOM   1279 H HG2  . MET A 1 99  ? 20.329  22.417 -14.049 1.00 16.71 ? 97  MET A HG2  1 
ATOM   1280 H HG3  . MET A 1 99  ? 20.836  23.910 -13.854 1.00 16.71 ? 97  MET A HG3  1 
ATOM   1281 H HE1  . MET A 1 99  ? 19.668  24.800 -10.418 1.00 18.76 ? 97  MET A HE1  1 
ATOM   1282 H HE2  . MET A 1 99  ? 20.455  25.316 -11.698 1.00 18.76 ? 97  MET A HE2  1 
ATOM   1283 H HE3  . MET A 1 99  ? 18.884  25.088 -11.769 1.00 18.76 ? 97  MET A HE3  1 
ATOM   1284 N N    . TYR A 1 100 ? 16.229  23.485 -16.130 1.00 13.09 ? 98  TYR A N    1 
ATOM   1285 C CA   . TYR A 1 100 ? 15.213  24.327 -16.774 1.00 15.83 ? 98  TYR A CA   1 
ATOM   1286 C C    . TYR A 1 100 ? 15.007  23.799 -18.177 1.00 16.42 ? 98  TYR A C    1 
ATOM   1287 O O    . TYR A 1 100 ? 15.956  23.319 -18.808 1.00 17.74 ? 98  TYR A O    1 
ATOM   1288 C CB   . TYR A 1 100 ? 15.616  25.809 -16.763 1.00 16.05 ? 98  TYR A CB   1 
ATOM   1289 C CG   . TYR A 1 100 ? 14.438  26.706 -16.496 1.00 20.44 ? 98  TYR A CG   1 
ATOM   1290 C CD1  . TYR A 1 100 ? 13.876  26.783 -15.237 1.00 18.58 ? 98  TYR A CD1  1 
ATOM   1291 C CD2  . TYR A 1 100 ? 13.833  27.435 -17.531 1.00 22.40 ? 98  TYR A CD2  1 
ATOM   1292 C CE1  . TYR A 1 100 ? 12.735  27.594 -14.992 1.00 21.29 ? 98  TYR A CE1  1 
ATOM   1293 C CE2  . TYR A 1 100 ? 12.681  28.226 -17.298 1.00 22.95 ? 98  TYR A CE2  1 
ATOM   1294 C CZ   . TYR A 1 100 ? 12.161  28.299 -16.018 1.00 24.95 ? 98  TYR A CZ   1 
ATOM   1295 O OH   . TYR A 1 100 ? 11.050  29.051 -15.752 1.00 29.20 ? 98  TYR A OH   1 
ATOM   1296 H H    . TYR A 1 100 ? 16.648  22.973 -16.679 1.00 15.77 ? 98  TYR A H    1 
ATOM   1297 H HA   . TYR A 1 100 ? 14.373  24.284 -16.292 1.00 19.06 ? 98  TYR A HA   1 
ATOM   1298 H HB2  . TYR A 1 100 ? 16.274  25.957 -16.066 1.00 19.32 ? 98  TYR A HB2  1 
ATOM   1299 H HB3  . TYR A 1 100 ? 15.989  26.046 -17.626 1.00 19.32 ? 98  TYR A HB3  1 
ATOM   1300 H HD1  . TYR A 1 100 ? 14.249  26.295 -14.539 1.00 22.35 ? 98  TYR A HD1  1 
ATOM   1301 H HD2  . TYR A 1 100 ? 14.196  27.399 -18.386 1.00 26.94 ? 98  TYR A HD2  1 
ATOM   1302 H HE1  . TYR A 1 100 ? 12.378  27.647 -14.134 1.00 25.61 ? 98  TYR A HE1  1 
ATOM   1303 H HE2  . TYR A 1 100 ? 12.279  28.690 -17.997 1.00 27.61 ? 98  TYR A HE2  1 
ATOM   1304 H HH   . TYR A 1 100 ? 10.522  29.024 -16.405 1.00 35.10 ? 98  TYR A HH   1 
ATOM   1305 N N    . PRO A 1 101 ? 13.778  23.819 -18.685 1.00 17.71 ? 99  PRO A N    1 
ATOM   1306 C CA   . PRO A 1 101 ? 12.553  24.286 -18.062 1.00 16.95 ? 99  PRO A CA   1 
ATOM   1307 C C    . PRO A 1 101 ? 12.091  23.271 -17.029 1.00 17.61 ? 99  PRO A C    1 
ATOM   1308 O O    . PRO A 1 101 ? 12.505  22.113 -16.982 1.00 16.33 ? 99  PRO A O    1 
ATOM   1309 C CB   . PRO A 1 101 ? 11.583  24.450 -19.258 1.00 22.31 ? 99  PRO A CB   1 
ATOM   1310 C CG   . PRO A 1 101 ? 12.212  23.805 -20.448 1.00 26.47 ? 99  PRO A CG   1 
ATOM   1311 C CD   . PRO A 1 101 ? 13.527  23.189 -19.991 1.00 21.69 ? 99  PRO A CD   1 
ATOM   1312 H HA   . PRO A 1 101 ? 12.650  25.161 -17.655 1.00 20.41 ? 99  PRO A HA   1 
ATOM   1313 H HB2  . PRO A 1 101 ? 10.741  24.018 -19.047 1.00 26.84 ? 99  PRO A HB2  1 
ATOM   1314 H HB3  . PRO A 1 101 ? 11.438  25.395 -19.424 1.00 26.84 ? 99  PRO A HB3  1 
ATOM   1315 H HG2  . PRO A 1 101 ? 11.618  23.119 -20.792 1.00 31.82 ? 99  PRO A HG2  1 
ATOM   1316 H HG3  . PRO A 1 101 ? 12.372  24.477 -21.130 1.00 31.82 ? 99  PRO A HG3  1 
ATOM   1317 H HD2  . PRO A 1 101 ? 13.441  22.228 -19.896 1.00 26.09 ? 99  PRO A HD2  1 
ATOM   1318 H HD3  . PRO A 1 101 ? 14.239  23.399 -20.615 1.00 26.09 ? 99  PRO A HD3  1 
ATOM   1319 N N    . PRO A 1 102 ? 11.174  23.679 -16.178 1.00 18.35 ? 100 PRO A N    1 
ATOM   1320 C CA   . PRO A 1 102 ? 10.701  22.787 -15.145 1.00 15.52 ? 100 PRO A CA   1 
ATOM   1321 C C    . PRO A 1 102 ? 9.968   21.592 -15.734 1.00 17.39 ? 100 PRO A C    1 
ATOM   1322 O O    . PRO A 1 102 ? 9.432   21.656 -16.858 1.00 15.96 ? 100 PRO A O    1 
ATOM   1323 C CB   . PRO A 1 102 ? 9.779   23.690 -14.305 1.00 19.04 ? 100 PRO A CB   1 
ATOM   1324 C CG   . PRO A 1 102 ? 9.409   24.794 -15.207 1.00 26.61 ? 100 PRO A CG   1 
ATOM   1325 C CD   . PRO A 1 102 ? 10.537  25.008 -16.112 1.00 20.65 ? 100 PRO A CD   1 
ATOM   1326 H HA   . PRO A 1 102 ? 11.429  22.464 -14.593 1.00 18.69 ? 100 PRO A HA   1 
ATOM   1327 H HB2  . PRO A 1 102 ? 8.995   23.193 -14.024 1.00 22.90 ? 100 PRO A HB2  1 
ATOM   1328 H HB3  . PRO A 1 102 ? 10.258  24.021 -13.529 1.00 22.90 ? 100 PRO A HB3  1 
ATOM   1329 H HG2  . PRO A 1 102 ? 8.615   24.548 -15.707 1.00 31.99 ? 100 PRO A HG2  1 
ATOM   1330 H HG3  . PRO A 1 102 ? 9.238   25.593 -14.684 1.00 31.99 ? 100 PRO A HG3  1 
ATOM   1331 H HD2  . PRO A 1 102 ? 10.229  25.287 -16.988 1.00 24.85 ? 100 PRO A HD2  1 
ATOM   1332 H HD3  . PRO A 1 102 ? 11.150  25.667 -15.750 1.00 24.85 ? 100 PRO A HD3  1 
ATOM   1333 N N    . PRO A 1 103 ? 9.875   20.495 -14.978 1.00 15.81 ? 101 PRO A N    1 
ATOM   1334 C CA   . PRO A 1 103 ? 10.380  20.361 -13.606 1.00 14.44 ? 101 PRO A CA   1 
ATOM   1335 C C    . PRO A 1 103 ? 11.876  20.333 -13.491 1.00 13.64 ? 101 PRO A C    1 
ATOM   1336 O O    . PRO A 1 103 ? 12.594  19.849 -14.348 1.00 12.25 ? 101 PRO A O    1 
ATOM   1337 C CB   . PRO A 1 103 ? 9.778   19.039 -13.119 1.00 19.83 ? 101 PRO A CB   1 
ATOM   1338 C CG   . PRO A 1 103 ? 8.999   18.439 -14.244 1.00 21.26 ? 101 PRO A CG   1 
ATOM   1339 C CD   . PRO A 1 103 ? 9.208   19.282 -15.458 1.00 17.55 ? 101 PRO A CD   1 
ATOM   1340 H HA   . PRO A 1 103 ? 10.031  21.105 -13.092 1.00 17.39 ? 101 PRO A HA   1 
ATOM   1341 H HB2  . PRO A 1 103 ? 10.496  18.444 -12.852 1.00 23.86 ? 101 PRO A HB2  1 
ATOM   1342 H HB3  . PRO A 1 103 ? 9.196   19.216 -12.364 1.00 23.86 ? 101 PRO A HB3  1 
ATOM   1343 H HG2  . PRO A 1 103 ? 9.317   17.536 -14.404 1.00 25.57 ? 101 PRO A HG2  1 
ATOM   1344 H HG3  . PRO A 1 103 ? 8.059   18.422 -14.005 1.00 25.57 ? 101 PRO A HG3  1 
ATOM   1345 H HD2  . PRO A 1 103 ? 9.771   18.819 -16.097 1.00 21.13 ? 101 PRO A HD2  1 
ATOM   1346 H HD3  . PRO A 1 103 ? 8.357   19.504 -15.865 1.00 21.13 ? 101 PRO A HD3  1 
ATOM   1347 N N    . TYR A 1 104 ? 12.366  20.915 -12.403 1.00 13.17 ? 102 TYR A N    1 
ATOM   1348 C CA   . TYR A 1 104 ? 13.697  20.608 -11.907 1.00 11.72 ? 102 TYR A CA   1 
ATOM   1349 C C    . TYR A 1 104 ? 13.784  19.131 -11.531 1.00 11.89 ? 102 TYR A C    1 
ATOM   1350 O O    . TYR A 1 104 ? 12.866  18.569 -10.906 1.00 11.25 ? 102 TYR A O    1 
ATOM   1351 C CB   . TYR A 1 104 ? 13.985  21.467 -10.677 1.00 10.26 ? 102 TYR A CB   1 
ATOM   1352 C CG   . TYR A 1 104 ? 15.205  21.122 -9.874  1.00 11.90 ? 102 TYR A CG   1 
ATOM   1353 C CD1  . TYR A 1 104 ? 16.441  21.744 -10.179 1.00 11.98 ? 102 TYR A CD1  1 
ATOM   1354 C CD2  . TYR A 1 104 ? 15.154  20.231 -8.811  1.00 9.97  ? 102 TYR A CD2  1 
ATOM   1355 C CE1  . TYR A 1 104 ? 17.591  21.476 -9.448  1.00 9.86  ? 102 TYR A CE1  1 
ATOM   1356 C CE2  . TYR A 1 104 ? 16.310  19.970 -8.036  1.00 14.15 ? 102 TYR A CE2  1 
ATOM   1357 C CZ   . TYR A 1 104 ? 17.525  20.593 -8.380  1.00 11.30 ? 102 TYR A CZ   1 
ATOM   1358 O OH   . TYR A 1 104 ? 18.670  20.359 -7.670  1.00 10.79 ? 102 TYR A OH   1 
ATOM   1359 H H    . TYR A 1 104 ? 11.944  21.496 -11.930 1.00 15.86 ? 102 TYR A H    1 
ATOM   1360 H HA   . TYR A 1 104 ? 14.361  20.796 -12.589 1.00 14.12 ? 102 TYR A HA   1 
ATOM   1361 H HB2  . TYR A 1 104 ? 14.091  22.385 -10.971 1.00 12.38 ? 102 TYR A HB2  1 
ATOM   1362 H HB3  . TYR A 1 104 ? 13.224  21.397 -10.079 1.00 12.38 ? 102 TYR A HB3  1 
ATOM   1363 H HD1  . TYR A 1 104 ? 16.483  22.346 -10.886 1.00 14.44 ? 102 TYR A HD1  1 
ATOM   1364 H HD2  . TYR A 1 104 ? 14.354  19.803 -8.606  1.00 12.03 ? 102 TYR A HD2  1 
ATOM   1365 H HE1  . TYR A 1 104 ? 18.396  21.885 -9.671  1.00 11.90 ? 102 TYR A HE1  1 
ATOM   1366 H HE2  . TYR A 1 104 ? 16.267  19.392 -7.309  1.00 17.04 ? 102 TYR A HE2  1 
ATOM   1367 H HH   . TYR A 1 104 ? 19.308  20.794 -8.001  1.00 13.01 ? 102 TYR A HH   1 
ATOM   1368 N N    . PHE A 1 105 ? 14.903  18.499 -11.865 1.00 12.81 ? 103 PHE A N    1 
ATOM   1369 C CA   . PHE A 1 105 ? 15.191  17.137 -11.430 1.00 10.35 ? 103 PHE A CA   1 
ATOM   1370 C C    . PHE A 1 105 ? 16.604  17.136 -10.848 1.00 11.36 ? 103 PHE A C    1 
ATOM   1371 O O    . PHE A 1 105 ? 17.507  17.800 -11.374 1.00 11.70 ? 103 PHE A O    1 
ATOM   1372 C CB   . PHE A 1 105 ? 15.164  16.111 -12.573 1.00 12.89 ? 103 PHE A CB   1 
ATOM   1373 C CG   . PHE A 1 105 ? 13.822  15.795 -13.114 1.00 11.62 ? 103 PHE A CG   1 
ATOM   1374 C CD1  . PHE A 1 105 ? 13.075  14.788 -12.562 1.00 14.00 ? 103 PHE A CD1  1 
ATOM   1375 C CD2  . PHE A 1 105 ? 13.325  16.494 -14.190 1.00 12.42 ? 103 PHE A CD2  1 
ATOM   1376 C CE1  . PHE A 1 105 ? 11.869  14.458 -13.064 1.00 13.89 ? 103 PHE A CE1  1 
ATOM   1377 C CE2  . PHE A 1 105 ? 12.061  16.165 -14.754 1.00 15.12 ? 103 PHE A CE2  1 
ATOM   1378 C CZ   . PHE A 1 105 ? 11.337  15.142 -14.155 1.00 13.09 ? 103 PHE A CZ   1 
ATOM   1379 H H    . PHE A 1 105 ? 15.522  18.844 -12.352 1.00 15.43 ? 103 PHE A H    1 
ATOM   1380 H HA   . PHE A 1 105 ? 14.524  16.870 -10.779 1.00 12.49 ? 103 PHE A HA   1 
ATOM   1381 H HB2  . PHE A 1 105 ? 15.697  16.457 -13.307 1.00 15.53 ? 103 PHE A HB2  1 
ATOM   1382 H HB3  . PHE A 1 105 ? 15.548  15.281 -12.248 1.00 15.53 ? 103 PHE A HB3  1 
ATOM   1383 H HD1  . PHE A 1 105 ? 13.405  14.324 -11.827 1.00 16.86 ? 103 PHE A HD1  1 
ATOM   1384 H HD2  . PHE A 1 105 ? 13.823  17.191 -14.554 1.00 14.96 ? 103 PHE A HD2  1 
ATOM   1385 H HE1  . PHE A 1 105 ? 11.385  13.764 -12.677 1.00 16.72 ? 103 PHE A HE1  1 
ATOM   1386 H HE2  . PHE A 1 105 ? 11.731  16.618 -15.496 1.00 18.21 ? 103 PHE A HE2  1 
ATOM   1387 H HZ   . PHE A 1 105 ? 10.497  14.913 -14.482 1.00 15.77 ? 103 PHE A HZ   1 
ATOM   1388 N N    . VAL A 1 106 ? 16.830  16.357 -9.805  1.00 10.70 ? 104 VAL A N    1 
ATOM   1389 C CA   . VAL A 1 106 ? 18.164  16.129 -9.280  1.00 9.83  ? 104 VAL A CA   1 
ATOM   1390 C C    . VAL A 1 106 ? 18.331  14.632 -9.082  1.00 14.46 ? 104 VAL A C    1 
ATOM   1391 O O    . VAL A 1 106 ? 17.412  13.965 -8.617  1.00 12.21 ? 104 VAL A O    1 
ATOM   1392 C CB   . VAL A 1 106 ? 18.424  16.916 -7.969  1.00 10.49 ? 104 VAL A CB   1 
ATOM   1393 C CG1  . VAL A 1 106 ? 17.443  16.550 -6.821  1.00 14.15 ? 104 VAL A CG1  1 
ATOM   1394 C CG2  . VAL A 1 106 ? 19.895  16.706 -7.536  1.00 13.60 ? 104 VAL A CG2  1 
ATOM   1395 H H    . VAL A 1 106 ? 16.213  15.941 -9.374  1.00 12.90 ? 104 VAL A H    1 
ATOM   1396 H HA   . VAL A 1 106 ? 18.826  16.430 -9.921  1.00 11.85 ? 104 VAL A HA   1 
ATOM   1397 H HB   . VAL A 1 106 ? 18.264  17.856 -8.148  1.00 12.65 ? 104 VAL A HB   1 
ATOM   1398 H HG11 . VAL A 1 106 ? 17.533  17.202 -6.108  1.00 17.05 ? 104 VAL A HG11 1 
ATOM   1399 H HG12 . VAL A 1 106 ? 16.536  16.560 -7.165  1.00 17.05 ? 104 VAL A HG12 1 
ATOM   1400 H HG13 . VAL A 1 106 ? 17.661  15.665 -6.489  1.00 17.05 ? 104 VAL A HG13 1 
ATOM   1401 H HG21 . VAL A 1 106 ? 20.123  17.365 -6.862  1.00 16.38 ? 104 VAL A HG21 1 
ATOM   1402 H HG22 . VAL A 1 106 ? 19.992  15.813 -7.172  1.00 16.38 ? 104 VAL A HG22 1 
ATOM   1403 H HG23 . VAL A 1 106 ? 20.470  16.812 -8.310  1.00 16.38 ? 104 VAL A HG23 1 
ATOM   1404 N N    . GLY A 1 107 ? 19.530  14.129 -9.366  1.00 12.16 ? 105 GLY A N    1 
ATOM   1405 C CA   . GLY A 1 107 ? 19.879  12.751 -9.077  1.00 11.54 ? 105 GLY A CA   1 
ATOM   1406 C C    . GLY A 1 107 ? 21.294  12.672 -8.543  1.00 12.98 ? 105 GLY A C    1 
ATOM   1407 O O    . GLY A 1 107 ? 22.177  13.399 -8.986  1.00 11.74 ? 105 GLY A O    1 
ATOM   1408 H H    . GLY A 1 107 ? 20.167  14.577 -9.732  1.00 14.65 ? 105 GLY A H    1 
ATOM   1409 H HA2  . GLY A 1 107 ? 19.270  12.390 -8.413  1.00 13.91 ? 105 GLY A HA2  1 
ATOM   1410 H HA3  . GLY A 1 107 ? 19.816  12.219 -9.885  1.00 13.91 ? 105 GLY A HA3  1 
ATOM   1411 N N    . MET A 1 108 ? 21.508  11.789 -7.582  1.00 14.94 ? 106 MET A N    1 
ATOM   1412 C CA   . MET A 1 108 ? 22.823  11.482 -7.046  1.00 14.58 ? 106 MET A CA   1 
ATOM   1413 C C    . MET A 1 108 ? 23.268  10.099 -7.514  1.00 12.69 ? 106 MET A C    1 
ATOM   1414 O O    . MET A 1 108 ? 22.538  9.117  -7.339  1.00 14.43 ? 106 MET A O    1 
ATOM   1415 C CB   . MET A 1 108 ? 22.826  11.492 -5.526  1.00 16.07 ? 106 MET A CB   1 
ATOM   1416 C CG   . MET A 1 108 ? 22.734  12.803 -4.730  1.00 15.88 ? 106 MET A CG   1 
ATOM   1417 S SD   . MET A 1 108 ? 23.828  14.100 -5.294  1.00 17.44 ? 106 MET A SD   1 
ATOM   1418 C CE   . MET A 1 108 ? 25.358  13.324 -5.012  1.00 19.03 ? 106 MET A CE   1 
ATOM   1419 H H    . MET A 1 108 ? 20.881  11.335 -7.208  1.00 17.99 ? 106 MET A H    1 
ATOM   1420 H HA   . MET A 1 108 ? 23.437  12.159 -7.370  1.00 17.56 ? 106 MET A HA   1 
ATOM   1421 H HB2  . MET A 1 108 ? 22.068  10.959 -5.240  1.00 19.34 ? 106 MET A HB2  1 
ATOM   1422 H HB3  . MET A 1 108 ? 23.653  11.072 -5.244  1.00 19.34 ? 106 MET A HB3  1 
ATOM   1423 H HG2  . MET A 1 108 ? 21.827  13.139 -4.793  1.00 19.12 ? 106 MET A HG2  1 
ATOM   1424 H HG3  . MET A 1 108 ? 22.956  12.617 -3.804  1.00 19.12 ? 106 MET A HG3  1 
ATOM   1425 H HE1  . MET A 1 108 ? 26.071  13.921 -5.290  1.00 22.90 ? 106 MET A HE1  1 
ATOM   1426 H HE2  . MET A 1 108 ? 25.443  13.127 -4.066  1.00 22.90 ? 106 MET A HE2  1 
ATOM   1427 H HE3  . MET A 1 108 ? 25.396  12.503 -5.527  1.00 22.90 ? 106 MET A HE3  1 
ATOM   1428 N N    . GLY A 1 109 ? 24.460  10.029 -8.094  1.00 15.47 ? 107 GLY A N    1 
ATOM   1429 C CA   . GLY A 1 109 ? 25.113  8.755  -8.251  1.00 16.78 ? 107 GLY A CA   1 
ATOM   1430 C C    . GLY A 1 109 ? 25.498  8.151  -6.915  1.00 16.96 ? 107 GLY A C    1 
ATOM   1431 O O    . GLY A 1 109 ? 25.514  8.794  -5.863  1.00 14.18 ? 107 GLY A O    1 
ATOM   1432 H H    . GLY A 1 109 ? 24.901  10.701 -8.399  1.00 18.63 ? 107 GLY A H    1 
ATOM   1433 H HA2  . GLY A 1 109 ? 24.517  8.140  -8.707  1.00 20.20 ? 107 GLY A HA2  1 
ATOM   1434 H HA3  . GLY A 1 109 ? 25.917  8.867  -8.782  1.00 20.20 ? 107 GLY A HA3  1 
ATOM   1435 N N    . ASN A 1 110 ? 25.799  6.862  -6.974  1.00 17.28 ? 108 ASN A N    1 
ATOM   1436 C CA   . ASN A 1 110 ? 26.265  6.079  -5.837  1.00 15.63 ? 108 ASN A CA   1 
ATOM   1437 C C    . ASN A 1 110 ? 27.729  6.251  -5.515  1.00 17.63 ? 108 ASN A C    1 
ATOM   1438 O O    . ASN A 1 110 ? 28.175  5.726  -4.495  1.00 21.28 ? 108 ASN A O    1 
ATOM   1439 C CB   . ASN A 1 110 ? 25.886  4.649  -6.143  1.00 20.13 ? 108 ASN A CB   1 
ATOM   1440 C CG   . ASN A 1 110 ? 24.466  4.266  -5.726  1.00 25.25 ? 108 ASN A CG   1 
ATOM   1441 O OD1  . ASN A 1 110 ? 23.818  4.889  -4.863  1.00 20.74 ? 108 ASN A OD1  1 
ATOM   1442 N ND2  . ASN A 1 110 ? 23.962  3.243  -6.384  1.00 22.61 ? 108 ASN A ND2  1 
ATOM   1443 H H    . ASN A 1 110 ? 25.740  6.395  -7.693  1.00 20.80 ? 108 ASN A H    1 
ATOM   1444 H HA   . ASN A 1 110 ? 25.834  6.352  -5.012  1.00 18.81 ? 108 ASN A HA   1 
ATOM   1445 H HB2  . ASN A 1 110 ? 25.958  4.508  -7.100  1.00 24.22 ? 108 ASN A HB2  1 
ATOM   1446 H HB3  . ASN A 1 110 ? 26.497  4.059  -5.674  1.00 24.22 ? 108 ASN A HB3  1 
ATOM   1447 H HD21 . ASN A 1 110 ? 24.390  2.894  -7.044  1.00 27.19 ? 108 ASN A HD21 1 
ATOM   1448 N N    . GLY A 1 111 ? 28.467  6.971  -6.348  1.00 15.79 ? 109 GLY A N    1 
ATOM   1449 C CA   . GLY A 1 111 ? 29.854  7.284  -6.091  1.00 17.36 ? 109 GLY A CA   1 
ATOM   1450 C C    . GLY A 1 111 ? 30.815  6.354  -6.806  1.00 17.63 ? 109 GLY A C    1 
ATOM   1451 O O    . GLY A 1 111 ? 30.588  5.143  -6.966  1.00 18.28 ? 109 GLY A O    1 
ATOM   1452 H H    . GLY A 1 111 ? 28.175  7.297  -7.089  1.00 19.00 ? 109 GLY A H    1 
ATOM   1453 H HA2  . GLY A 1 111 ? 30.036  8.191  -6.384  1.00 20.90 ? 109 GLY A HA2  1 
ATOM   1454 H HA3  . GLY A 1 111 ? 30.023  7.220  -5.138  1.00 20.90 ? 109 GLY A HA3  1 
ATOM   1455 N N    . THR A 1 112 ? 31.910  6.960  -7.245  1.00 18.54 ? 110 THR A N    1 
ATOM   1456 C CA   . THR A 1 112 ? 33.025  6.271  -7.870  1.00 18.16 ? 110 THR A CA   1 
ATOM   1457 C C    . THR A 1 112 ? 34.207  6.313  -6.917  1.00 19.94 ? 110 THR A C    1 
ATOM   1458 O O    . THR A 1 112 ? 34.676  7.389  -6.541  1.00 19.48 ? 110 THR A O    1 
ATOM   1459 C CB   . THR A 1 112 ? 33.381  6.927  -9.190  1.00 19.08 ? 110 THR A CB   1 
ATOM   1460 O OG1  . THR A 1 112 ? 32.285  6.798  -10.098 1.00 19.15 ? 110 THR A OG1  1 
ATOM   1461 C CG2  . THR A 1 112 ? 34.650  6.275  -9.778  1.00 23.35 ? 110 THR A CG2  1 
ATOM   1462 H H    . THR A 1 112 ? 32.034  7.809  -7.188  1.00 22.31 ? 110 THR A H    1 
ATOM   1463 H HA   . THR A 1 112 ? 32.793  5.344  -8.038  1.00 21.85 ? 110 THR A HA   1 
ATOM   1464 H HB   . THR A 1 112 ? 33.563  7.871  -9.058  1.00 22.96 ? 110 THR A HB   1 
ATOM   1465 H HG1  . THR A 1 112 ? 32.200  5.996  -10.334 1.00 23.04 ? 110 THR A HG1  1 
ATOM   1466 H HG21 . THR A 1 112 ? 34.631  6.327  -10.747 1.00 28.08 ? 110 THR A HG21 1 
ATOM   1467 H HG22 . THR A 1 112 ? 35.440  6.736  -9.454  1.00 28.08 ? 110 THR A HG22 1 
ATOM   1468 H HG23 . THR A 1 112 ? 34.698  5.344  -9.513  1.00 28.08 ? 110 THR A HG23 1 
ATOM   1469 N N    . GLN A 1 113 ? 34.663  5.144  -6.505  1.00 20.34 ? 111 GLN A N    1 
ATOM   1470 C CA   . GLN A 1 113 ? 35.850  5.059  -5.676  1.00 19.31 ? 111 GLN A CA   1 
ATOM   1471 C C    . GLN A 1 113 ? 37.042  5.213  -6.594  1.00 22.53 ? 111 GLN A C    1 
ATOM   1472 O O    . GLN A 1 113 ? 37.215  4.410  -7.515  1.00 20.99 ? 111 GLN A O    1 
ATOM   1473 C CB   . GLN A 1 113 ? 35.879  3.725  -4.932  1.00 24.39 ? 111 GLN A CB   1 
ATOM   1474 C CG   . GLN A 1 113 ? 37.189  3.479  -4.156  1.00 21.72 ? 111 GLN A CG   1 
ATOM   1475 C CD   . GLN A 1 113 ? 37.343  4.360  -2.953  1.00 28.03 ? 111 GLN A CD   1 
ATOM   1476 O OE1  . GLN A 1 113 ? 36.363  4.844  -2.362  1.00 26.25 ? 111 GLN A OE1  1 
ATOM   1477 N NE2  . GLN A 1 113 ? 38.594  4.575  -2.569  1.00 29.96 ? 111 GLN A NE2  1 
ATOM   1478 H H    . GLN A 1 113 ? 34.304  4.385  -6.692  1.00 24.47 ? 111 GLN A H    1 
ATOM   1479 H HA   . GLN A 1 113 ? 35.866  5.758  -5.004  1.00 23.23 ? 111 GLN A HA   1 
ATOM   1480 H HB2  . GLN A 1 113 ? 35.148  3.708  -4.294  1.00 29.33 ? 111 GLN A HB2  1 
ATOM   1481 H HB3  . GLN A 1 113 ? 35.775  3.006  -5.575  1.00 29.33 ? 111 GLN A HB3  1 
ATOM   1482 H HG2  . GLN A 1 113 ? 37.206  2.558  -3.854  1.00 26.12 ? 111 GLN A HG2  1 
ATOM   1483 H HG3  . GLN A 1 113 ? 37.940  3.649  -4.746  1.00 26.12 ? 111 GLN A HG3  1 
ATOM   1484 H HE21 . GLN A 1 113 ? 39.245  4.218  -3.004  1.00 36.01 ? 111 GLN A HE21 1 
ATOM   1485 H HE22 . GLN A 1 113 ? 38.755  5.071  -1.886  1.00 36.01 ? 111 GLN A HE22 1 
ATOM   1486 N N    . ILE A 1 114 ? 37.852  6.232  -6.363  1.00 20.66 ? 112 ILE A N    1 
ATOM   1487 C CA   . ILE A 1 114 ? 39.011  6.501  -7.197  1.00 22.11 ? 112 ILE A CA   1 
ATOM   1488 C C    . ILE A 1 114 ? 40.235  6.122  -6.390  1.00 19.78 ? 112 ILE A C    1 
ATOM   1489 O O    . ILE A 1 114 ? 40.471  6.679  -5.309  1.00 24.08 ? 112 ILE A O    1 
ATOM   1490 C CB   . ILE A 1 114 ? 39.092  7.971  -7.637  1.00 21.04 ? 112 ILE A CB   1 
ATOM   1491 C CG1  . ILE A 1 114 ? 37.791  8.422  -8.308  1.00 21.82 ? 112 ILE A CG1  1 
ATOM   1492 C CG2  . ILE A 1 114 ? 40.295  8.163  -8.555  1.00 21.50 ? 112 ILE A CG2  1 
ATOM   1493 C CD1  . ILE A 1 114 ? 37.865  9.835  -8.844  1.00 18.47 ? 112 ILE A CD1  1 
ATOM   1494 H H    . ILE A 1 114 ? 37.749  6.791  -5.717  1.00 24.85 ? 112 ILE A H    1 
ATOM   1495 H HA   . ILE A 1 114 ? 38.962  5.954  -7.996  1.00 26.59 ? 112 ILE A HA   1 
ATOM   1496 H HB   . ILE A 1 114 ? 39.208  8.526  -6.850  1.00 25.30 ? 112 ILE A HB   1 
ATOM   1497 H HG12 . ILE A 1 114 ? 37.598  7.829  -9.052  1.00 26.24 ? 112 ILE A HG12 1 
ATOM   1498 H HG13 . ILE A 1 114 ? 37.071  8.384  -7.659  1.00 26.24 ? 112 ILE A HG13 1 
ATOM   1499 H HG21 . ILE A 1 114 ? 40.419  9.111  -8.719  1.00 25.86 ? 112 ILE A HG21 1 
ATOM   1500 H HG22 . ILE A 1 114 ? 41.083  7.797  -8.124  1.00 25.86 ? 112 ILE A HG22 1 
ATOM   1501 H HG23 . ILE A 1 114 ? 40.131  7.701  -9.392  1.00 25.86 ? 112 ILE A HG23 1 
ATOM   1502 H HD11 . ILE A 1 114 ? 36.965  10.166 -8.987  1.00 22.23 ? 112 ILE A HD11 1 
ATOM   1503 H HD12 . ILE A 1 114 ? 38.324  10.393 -8.197  1.00 22.23 ? 112 ILE A HD12 1 
ATOM   1504 H HD13 . ILE A 1 114 ? 38.353  9.830  -9.682  1.00 22.23 ? 112 ILE A HD13 1 
ATOM   1505 N N    . TYR A 1 115 ? 41.016  5.194  -6.921  1.00 25.08 ? 113 TYR A N    1 
ATOM   1506 C CA   . TYR A 1 115 ? 42.277  4.805  -6.315  1.00 25.16 ? 113 TYR A CA   1 
ATOM   1507 C C    . TYR A 1 115 ? 43.409  5.517  -7.036  1.00 22.11 ? 113 TYR A C    1 
ATOM   1508 O O    . TYR A 1 115 ? 43.541  5.427  -8.267  1.00 24.01 ? 113 TYR A O    1 
ATOM   1509 C CB   . TYR A 1 115 ? 42.455  3.297  -6.384  1.00 22.69 ? 113 TYR A CB   1 
ATOM   1510 C CG   . TYR A 1 115 ? 41.519  2.555  -5.484  1.00 25.02 ? 113 TYR A CG   1 
ATOM   1511 C CD1  . TYR A 1 115 ? 41.680  2.600  -4.116  1.00 26.86 ? 113 TYR A CD1  1 
ATOM   1512 C CD2  . TYR A 1 115 ? 40.449  1.835  -5.999  1.00 26.19 ? 113 TYR A CD2  1 
ATOM   1513 C CE1  . TYR A 1 115 ? 40.817  1.918  -3.264  1.00 29.63 ? 113 TYR A CE1  1 
ATOM   1514 C CE2  . TYR A 1 115 ? 39.603  1.164  -5.175  1.00 24.37 ? 113 TYR A CE2  1 
ATOM   1515 C CZ   . TYR A 1 115 ? 39.789  1.208  -3.802  1.00 28.91 ? 113 TYR A CZ   1 
ATOM   1516 O OH   . TYR A 1 115 ? 38.941  0.503  -2.988  1.00 32.03 ? 113 TYR A OH   1 
ATOM   1517 H H    . TYR A 1 115 ? 40.833  4.768  -7.645  1.00 30.15 ? 113 TYR A H    1 
ATOM   1518 H HA   . TYR A 1 115 ? 42.300  5.066  -5.381  1.00 30.25 ? 113 TYR A HA   1 
ATOM   1519 H HB2  . TYR A 1 115 ? 42.291  3.003  -7.294  1.00 27.29 ? 113 TYR A HB2  1 
ATOM   1520 H HB3  . TYR A 1 115 ? 43.362  3.075  -6.122  1.00 27.29 ? 113 TYR A HB3  1 
ATOM   1521 H HD1  . TYR A 1 115 ? 42.378  3.097  -3.755  1.00 32.29 ? 113 TYR A HD1  1 
ATOM   1522 H HD2  . TYR A 1 115 ? 40.309  1.812  -6.918  1.00 31.49 ? 113 TYR A HD2  1 
ATOM   1523 H HE1  . TYR A 1 115 ? 40.941  1.947  -2.343  1.00 35.62 ? 113 TYR A HE1  1 
ATOM   1524 H HE2  . TYR A 1 115 ? 38.898  0.675  -5.532  1.00 29.30 ? 113 TYR A HE2  1 
ATOM   1525 H HH   . TYR A 1 115 ? 38.356  0.115  -3.449  1.00 38.50 ? 113 TYR A HH   1 
ATOM   1526 N N    . VAL A 1 116 ? 44.231  6.206  -6.256  1.00 26.72 ? 114 VAL A N    1 
ATOM   1527 C CA   . VAL A 1 116 ? 45.347  6.994  -6.751  1.00 29.18 ? 114 VAL A CA   1 
ATOM   1528 C C    . VAL A 1 116 ? 46.613  6.442  -6.113  1.00 32.64 ? 114 VAL A C    1 
ATOM   1529 O O    . VAL A 1 116 ? 46.671  6.287  -4.886  1.00 31.55 ? 114 VAL A O    1 
ATOM   1530 C CB   . VAL A 1 116 ? 45.198  8.486  -6.403  1.00 31.14 ? 114 VAL A CB   1 
ATOM   1531 C CG1  . VAL A 1 116 ? 46.290  9.301  -7.077  1.00 28.33 ? 114 VAL A CG1  1 
ATOM   1532 C CG2  . VAL A 1 116 ? 43.811  9.029  -6.805  1.00 28.33 ? 114 VAL A CG2  1 
ATOM   1533 H H    . VAL A 1 116 ? 44.157  6.233  -5.400  1.00 32.12 ? 114 VAL A H    1 
ATOM   1534 H HA   . VAL A 1 116 ? 45.398  6.906  -7.716  1.00 35.07 ? 114 VAL A HA   1 
ATOM   1535 H HB   . VAL A 1 116 ? 45.283  8.576  -5.441  1.00 37.43 ? 114 VAL A HB   1 
ATOM   1536 H HG11 . VAL A 1 116 ? 45.998  10.223 -7.148  1.00 34.05 ? 114 VAL A HG11 1 
ATOM   1537 H HG12 . VAL A 1 116 ? 47.098  9.251  -6.542  1.00 34.05 ? 114 VAL A HG12 1 
ATOM   1538 H HG13 . VAL A 1 116 ? 46.456  8.938  -7.961  1.00 34.05 ? 114 VAL A HG13 1 
ATOM   1539 H HG21 . VAL A 1 116 ? 43.825  9.997  -6.758  1.00 34.06 ? 114 VAL A HG21 1 
ATOM   1540 H HG22 . VAL A 1 116 ? 43.610  8.744  -7.710  1.00 34.06 ? 114 VAL A HG22 1 
ATOM   1541 H HG23 . VAL A 1 116 ? 43.145  8.678  -6.193  1.00 34.06 ? 114 VAL A HG23 1 
ATOM   1542 N N    . ILE A 1 117 ? 47.617  6.145  -6.935  1.00 38.11 ? 115 ILE A N    1 
ATOM   1543 C CA   . ILE A 1 117 ? 48.902  5.659  -6.440  1.00 44.14 ? 115 ILE A CA   1 
ATOM   1544 C C    . ILE A 1 117 ? 50.003  6.643  -6.812  1.00 43.42 ? 115 ILE A C    1 
ATOM   1545 O O    . ILE A 1 117 ? 50.135  7.033  -7.978  1.00 47.35 ? 115 ILE A O    1 
ATOM   1546 C CB   . ILE A 1 117 ? 49.229  4.258  -6.978  1.00 42.02 ? 115 ILE A CB   1 
ATOM   1547 C CG1  . ILE A 1 117 ? 48.145  3.259  -6.539  1.00 41.34 ? 115 ILE A CG1  1 
ATOM   1548 C CG2  . ILE A 1 117 ? 50.629  3.840  -6.517  1.00 44.79 ? 115 ILE A CG2  1 
ATOM   1549 C CD1  . ILE A 1 117 ? 48.037  3.084  -5.017  1.00 41.68 ? 115 ILE A CD1  1 
ATOM   1550 H H    . ILE A 1 117 ? 47.576  6.218  -7.791  1.00 45.80 ? 115 ILE A H    1 
ATOM   1551 H HA   . ILE A 1 117 ? 48.855  5.622  -5.472  1.00 53.03 ? 115 ILE A HA   1 
ATOM   1552 H HB   . ILE A 1 117 ? 49.232  4.271  -7.948  1.00 50.48 ? 115 ILE A HB   1 
ATOM   1553 H HG12 . ILE A 1 117 ? 47.285  3.571  -6.862  1.00 49.67 ? 115 ILE A HG12 1 
ATOM   1554 H HG13 . ILE A 1 117 ? 48.348  2.391  -6.922  1.00 49.67 ? 115 ILE A HG13 1 
ATOM   1555 H HG21 . ILE A 1 117 ? 50.826  2.956  -6.865  1.00 53.81 ? 115 ILE A HG21 1 
ATOM   1556 H HG22 . ILE A 1 117 ? 51.276  4.479  -6.853  1.00 53.81 ? 115 ILE A HG22 1 
ATOM   1557 H HG23 . ILE A 1 117 ? 50.651  3.826  -5.547  1.00 53.81 ? 115 ILE A HG23 1 
ATOM   1558 H HD11 . ILE A 1 117 ? 47.336  2.443  -4.822  1.00 50.08 ? 115 ILE A HD11 1 
ATOM   1559 H HD12 . ILE A 1 117 ? 48.886  2.762  -4.676  1.00 50.08 ? 115 ILE A HD12 1 
ATOM   1560 H HD13 . ILE A 1 117 ? 47.823  3.941  -4.616  1.00 50.08 ? 115 ILE A HD13 1 
ATOM   1561 N N    . ASP A 1 118 ? 50.799  7.019  -5.815  1.00 47.82 ? 116 ASP A N    1 
ATOM   1562 C CA   . ASP A 1 118 ? 51.963  7.883  -6.001  1.00 52.11 ? 116 ASP A CA   1 
ATOM   1563 C C    . ASP A 1 118 ? 53.144  7.082  -6.556  1.00 46.39 ? 116 ASP A C    1 
ATOM   1564 O O    . ASP A 1 118 ? 53.743  6.269  -5.836  1.00 48.97 ? 116 ASP A O    1 
ATOM   1565 C CB   . ASP A 1 118 ? 52.343  8.552  -4.670  1.00 49.06 ? 116 ASP A CB   1 
ATOM   1566 C CG   . ASP A 1 118 ? 51.436  9.721  -4.311  1.00 51.46 ? 116 ASP A CG   1 
ATOM   1567 O OD1  . ASP A 1 118 ? 50.680  10.194 -5.190  1.00 49.57 ? 116 ASP A OD1  1 
ATOM   1568 O OD2  . ASP A 1 118 ? 51.467  10.147 -3.141  1.00 46.60 ? 116 ASP A OD2  1 
ATOM   1569 H H    . ASP A 1 118 ? 50.684  6.781  -4.997  1.00 57.44 ? 116 ASP A H    1 
ATOM   1570 H HA   . ASP A 1 118 ? 51.752  8.584  -6.637  1.00 62.59 ? 116 ASP A HA   1 
ATOM   1571 H HB2  . ASP A 1 118 ? 52.280  7.896  -3.958  1.00 58.93 ? 116 ASP A HB2  1 
ATOM   1572 H HB3  . ASP A 1 118 ? 53.251  8.887  -4.733  1.00 58.93 ? 116 ASP A HB3  1 
ATOM   1573 N N    . GLN B 2 1   ? 28.112  29.274 12.324  1.00 36.07 ? 1   GLN H N    1 
ATOM   1574 C CA   . GLN B 2 1   ? 26.934  28.352 12.328  1.00 34.20 ? 1   GLN H CA   1 
ATOM   1575 C C    . GLN B 2 1   ? 25.867  28.758 11.302  1.00 29.26 ? 1   GLN H C    1 
ATOM   1576 O O    . GLN B 2 1   ? 25.662  29.936 11.047  1.00 29.48 ? 1   GLN H O    1 
ATOM   1577 C CB   . GLN B 2 1   ? 26.353  28.303 13.742  1.00 39.48 ? 1   GLN H CB   1 
ATOM   1578 H HA   . GLN B 2 1   ? 27.217  27.460 12.070  1.00 41.11 ? 1   GLN H HA   1 
ATOM   1579 N N    . VAL B 2 2   ? 25.216  27.774 10.686  1.00 27.71 ? 2   VAL H N    1 
ATOM   1580 C CA   . VAL B 2 2   ? 24.200  28.065 9.678   1.00 25.36 ? 2   VAL H CA   1 
ATOM   1581 C C    . VAL B 2 2   ? 22.998  28.690 10.361  1.00 30.20 ? 2   VAL H C    1 
ATOM   1582 O O    . VAL B 2 2   ? 22.422  28.115 11.289  1.00 32.94 ? 2   VAL H O    1 
ATOM   1583 C CB   . VAL B 2 2   ? 23.790  26.798 8.910   1.00 28.93 ? 2   VAL H CB   1 
ATOM   1584 C CG1  . VAL B 2 2   ? 22.628  27.109 7.997   1.00 26.88 ? 2   VAL H CG1  1 
ATOM   1585 C CG2  . VAL B 2 2   ? 24.945  26.245 8.129   1.00 27.97 ? 2   VAL H CG2  1 
ATOM   1586 H H    . VAL B 2 2   ? 25.343  26.936 10.832  1.00 33.31 ? 2   VAL H H    1 
ATOM   1587 H HA   . VAL B 2 2   ? 24.568  28.700 9.044   1.00 30.49 ? 2   VAL H HA   1 
ATOM   1588 H HB   . VAL B 2 2   ? 23.515  26.117 9.543   1.00 34.78 ? 2   VAL H HB   1 
ATOM   1589 H HG11 . VAL B 2 2   ? 22.575  26.428 7.309   1.00 32.32 ? 2   VAL H HG11 1 
ATOM   1590 H HG12 . VAL B 2 2   ? 21.810  27.117 8.518   1.00 32.32 ? 2   VAL H HG12 1 
ATOM   1591 H HG13 . VAL B 2 2   ? 22.769  27.979 7.591   1.00 32.32 ? 2   VAL H HG13 1 
ATOM   1592 H HG21 . VAL B 2 2   ? 24.670  25.420 7.700   1.00 33.62 ? 2   VAL H HG21 1 
ATOM   1593 H HG22 . VAL B 2 2   ? 25.213  26.893 7.459   1.00 33.62 ? 2   VAL H HG22 1 
ATOM   1594 H HG23 . VAL B 2 2   ? 25.682  26.073 8.736   1.00 33.62 ? 2   VAL H HG23 1 
ATOM   1595 N N    . GLN B 2 3   ? 22.611  29.869 9.908   1.00 24.20 ? 3   GLN H N    1 
ATOM   1596 C CA   . GLN B 2 3   ? 21.380  30.464 10.372  1.00 29.67 ? 3   GLN H CA   1 
ATOM   1597 C C    . GLN B 2 3   ? 20.650  31.103 9.203   1.00 25.19 ? 3   GLN H C    1 
ATOM   1598 O O    . GLN B 2 3   ? 21.248  31.606 8.241   1.00 21.51 ? 3   GLN H O    1 
ATOM   1599 C CB   . GLN B 2 3   ? 21.606  31.460 11.538  1.00 36.53 ? 3   GLN H CB   1 
ATOM   1600 H H    . GLN B 2 3   ? 23.045  30.340 9.335   1.00 29.10 ? 3   GLN H H    1 
ATOM   1601 H HA   . GLN B 2 3   ? 20.794  29.772 10.719  1.00 35.66 ? 3   GLN H HA   1 
ATOM   1602 N N    . LEU B 2 4   ? 19.336  31.059 9.314   1.00 21.07 ? 4   LEU H N    1 
ATOM   1603 C CA   . LEU B 2 4   ? 18.399  31.641 8.377   1.00 23.68 ? 4   LEU H CA   1 
ATOM   1604 C C    . LEU B 2 4   ? 17.372  32.381 9.213   1.00 20.60 ? 4   LEU H C    1 
ATOM   1605 O O    . LEU B 2 4   ? 16.826  31.798 10.153  1.00 22.44 ? 4   LEU H O    1 
ATOM   1606 C CB   . LEU B 2 4   ? 17.696  30.564 7.561   1.00 18.25 ? 4   LEU H CB   1 
ATOM   1607 C CG   . LEU B 2 4   ? 18.582  29.724 6.654   1.00 16.53 ? 4   LEU H CG   1 
ATOM   1608 C CD1  . LEU B 2 4   ? 17.829  28.459 6.181   1.00 20.22 ? 4   LEU H CD1  1 
ATOM   1609 C CD2  . LEU B 2 4   ? 19.100  30.465 5.486   1.00 19.65 ? 4   LEU H CD2  1 
ATOM   1610 H H    . LEU B 2 4   ? 18.937  30.670 9.969   1.00 25.35 ? 4   LEU H H    1 
ATOM   1611 H HA   . LEU B 2 4   ? 18.847  32.242 7.761   1.00 28.48 ? 4   LEU H HA   1 
ATOM   1612 H HB2  . LEU B 2 4   ? 17.259  29.956 8.177   1.00 21.96 ? 4   LEU H HB2  1 
ATOM   1613 H HB3  . LEU B 2 4   ? 17.036  30.996 6.997   1.00 21.96 ? 4   LEU H HB3  1 
ATOM   1614 H HG   . LEU B 2 4   ? 19.355  29.467 7.181   1.00 19.89 ? 4   LEU H HG   1 
ATOM   1615 H HD11 . LEU B 2 4   ? 18.401  27.957 5.579   1.00 24.32 ? 4   LEU H HD11 1 
ATOM   1616 H HD12 . LEU B 2 4   ? 17.606  27.916 6.954   1.00 24.32 ? 4   LEU H HD12 1 
ATOM   1617 H HD13 . LEU B 2 4   ? 17.018  28.727 5.720   1.00 24.32 ? 4   LEU H HD13 1 
ATOM   1618 H HD21 . LEU B 2 4   ? 19.651  29.871 4.954   1.00 23.64 ? 4   LEU H HD21 1 
ATOM   1619 H HD22 . LEU B 2 4   ? 18.351  30.784 4.957   1.00 23.64 ? 4   LEU H HD22 1 
ATOM   1620 H HD23 . LEU B 2 4   ? 19.628  31.217 5.797   1.00 23.64 ? 4   LEU H HD23 1 
ATOM   1621 N N    . VAL B 2 5   ? 17.116  33.653 8.899   1.00 20.00 ? 5   VAL H N    1 
ATOM   1622 C CA   . VAL B 2 5   ? 16.239  34.483 9.700   1.00 17.72 ? 5   VAL H CA   1 
ATOM   1623 C C    . VAL B 2 5   ? 15.231  35.196 8.807   1.00 18.99 ? 5   VAL H C    1 
ATOM   1624 O O    . VAL B 2 5   ? 15.595  36.085 8.025   1.00 22.23 ? 5   VAL H O    1 
ATOM   1625 C CB   . VAL B 2 5   ? 17.018  35.498 10.560  1.00 20.06 ? 5   VAL H CB   1 
ATOM   1626 C CG1  . VAL B 2 5   ? 16.030  36.300 11.390  1.00 24.08 ? 5   VAL H CG1  1 
ATOM   1627 C CG2  . VAL B 2 5   ? 18.040  34.785 11.459  1.00 24.99 ? 5   VAL H CG2  1 
ATOM   1628 H H    . VAL B 2 5   ? 17.448  34.055 8.215   1.00 24.06 ? 5   VAL H H    1 
ATOM   1629 H HA   . VAL B 2 5   ? 15.728  33.894 10.277  1.00 21.32 ? 5   VAL H HA   1 
ATOM   1630 H HB   . VAL B 2 5   ? 17.515  36.101 9.986   1.00 24.14 ? 5   VAL H HB   1 
ATOM   1631 H HG11 . VAL B 2 5   ? 16.521  36.853 12.018  1.00 28.95 ? 5   VAL H HG11 1 
ATOM   1632 H HG12 . VAL B 2 5   ? 15.502  36.859 10.799  1.00 28.95 ? 5   VAL H HG12 1 
ATOM   1633 H HG13 . VAL B 2 5   ? 15.452  35.687 11.871  1.00 28.95 ? 5   VAL H HG13 1 
ATOM   1634 H HG21 . VAL B 2 5   ? 18.418  35.428 12.079  1.00 30.05 ? 5   VAL H HG21 1 
ATOM   1635 H HG22 . VAL B 2 5   ? 17.591  34.078 11.949  1.00 30.05 ? 5   VAL H HG22 1 
ATOM   1636 H HG23 . VAL B 2 5   ? 18.741  34.409 10.904  1.00 30.05 ? 5   VAL H HG23 1 
ATOM   1637 N N    . GLU B 2 6   ? 13.970  34.811 8.928   1.00 17.98 ? 6   GLU H N    1 
ATOM   1638 C CA   . GLU B 2 6   ? 12.906  35.397 8.126   1.00 18.41 ? 6   GLU H CA   1 
ATOM   1639 C C    . GLU B 2 6   ? 12.395  36.669 8.786   1.00 22.51 ? 6   GLU H C    1 
ATOM   1640 O O    . GLU B 2 6   ? 12.427  36.809 10.011  1.00 22.86 ? 6   GLU H O    1 
ATOM   1641 C CB   . GLU B 2 6   ? 11.732  34.437 7.926   1.00 20.66 ? 6   GLU H CB   1 
ATOM   1642 C CG   . GLU B 2 6   ? 12.124  33.087 7.318   1.00 18.66 ? 6   GLU H CG   1 
ATOM   1643 C CD   . GLU B 2 6   ? 12.478  32.072 8.375   1.00 19.23 ? 6   GLU H CD   1 
ATOM   1644 O OE1  . GLU B 2 6   ? 12.878  32.466 9.509   1.00 19.52 ? 6   GLU H OE1  1 
ATOM   1645 O OE2  . GLU B 2 6   ? 12.383  30.872 8.069   1.00 17.63 ? 6   GLU H OE2  1 
ATOM   1646 H H    . GLU B 2 6   ? 13.700  34.204 9.475   1.00 21.64 ? 6   GLU H H    1 
ATOM   1647 H HA   . GLU B 2 6   ? 13.267  35.603 7.250   1.00 22.16 ? 6   GLU H HA   1 
ATOM   1648 H HB2  . GLU B 2 6   ? 11.322  34.264 8.788   1.00 24.86 ? 6   GLU H HB2  1 
ATOM   1649 H HB3  . GLU B 2 6   ? 11.089  34.853 7.331   1.00 24.86 ? 6   GLU H HB3  1 
ATOM   1650 H HG2  . GLU B 2 6   ? 11.379  32.741 6.803   1.00 22.46 ? 6   GLU H HG2  1 
ATOM   1651 H HG3  . GLU B 2 6   ? 12.897  33.208 6.744   1.00 22.46 ? 6   GLU H HG3  1 
ATOM   1652 N N    . SER B 2 7   ? 11.884  37.577 7.962   1.00 23.23 ? 7   SER H N    1 
ATOM   1653 C CA   . SER B 2 7   ? 11.226  38.777 8.466   1.00 22.77 ? 7   SER H CA   1 
ATOM   1654 C C    . SER B 2 7   ? 10.220  39.281 7.451   1.00 23.32 ? 7   SER H C    1 
ATOM   1655 O O    . SER B 2 7   ? 10.214  38.888 6.277   1.00 19.21 ? 7   SER H O    1 
ATOM   1656 C CB   . SER B 2 7   ? 12.255  39.871 8.795   1.00 25.23 ? 7   SER H CB   1 
ATOM   1657 O OG   . SER B 2 7   ? 13.035  40.181 7.648   1.00 28.78 ? 7   SER H OG   1 
ATOM   1658 H H    . SER B 2 7   ? 11.905  37.521 7.104   1.00 27.94 ? 7   SER H H    1 
ATOM   1659 H HA   . SER B 2 7   ? 10.734  38.553 9.272   1.00 27.39 ? 7   SER H HA   1 
ATOM   1660 H HB2  . SER B 2 7   ? 11.787  40.669 9.086   1.00 30.33 ? 7   SER H HB2  1 
ATOM   1661 H HB3  . SER B 2 7   ? 12.840  39.554 9.501   1.00 30.33 ? 7   SER H HB3  1 
ATOM   1662 H HG   . SER B 2 7   ? 13.613  40.759 7.842   1.00 34.59 ? 7   SER H HG   1 
ATOM   1663 N N    . GLY B 2 8   ? 9.343   40.154 7.929   1.00 22.29 ? 8   GLY H N    1 
ATOM   1664 C CA   . GLY B 2 8   ? 8.357   40.800 7.082   1.00 23.31 ? 8   GLY H CA   1 
ATOM   1665 C C    . GLY B 2 8   ? 6.923   40.366 7.259   1.00 20.75 ? 8   GLY H C    1 
ATOM   1666 O O    . GLY B 2 8   ? 6.025   40.959 6.643   1.00 21.07 ? 8   GLY H O    1 
ATOM   1667 H H    . GLY B 2 8   ? 9.300   40.390 8.755   1.00 26.81 ? 8   GLY H H    1 
ATOM   1668 H HA2  . GLY B 2 8   ? 8.391   41.755 7.251   1.00 28.03 ? 8   GLY H HA2  1 
ATOM   1669 H HA3  . GLY B 2 8   ? 8.596   40.634 6.157   1.00 28.03 ? 8   GLY H HA3  1 
ATOM   1670 N N    . GLY B 2 9   ? 6.661   39.316 8.019   1.00 19.08 ? 9   GLY H N    1 
ATOM   1671 C CA   . GLY B 2 9   ? 5.296   38.906 8.199   1.00 19.43 ? 9   GLY H CA   1 
ATOM   1672 C C    . GLY B 2 9   ? 4.474   39.912 8.991   1.00 20.57 ? 9   GLY H C    1 
ATOM   1673 O O    . GLY B 2 9   ? 4.977   40.779 9.698   1.00 23.78 ? 9   GLY H O    1 
ATOM   1674 H H    . GLY B 2 9   ? 7.247   38.840 8.430   1.00 22.96 ? 9   GLY H H    1 
ATOM   1675 H HA2  . GLY B 2 9   ? 4.880   38.792 7.331   1.00 23.37 ? 9   GLY H HA2  1 
ATOM   1676 H HA3  . GLY B 2 9   ? 5.278   38.060 8.672   1.00 23.37 ? 9   GLY H HA3  1 
ATOM   1677 N N    . GLY B 2 10  ? 3.165   39.767 8.878   1.00 20.86 ? 10  GLY H N    1 
ATOM   1678 C CA   . GLY B 2 10  ? 2.227   40.621 9.580   1.00 22.83 ? 10  GLY H CA   1 
ATOM   1679 C C    . GLY B 2 10  ? 0.843   40.442 8.993   1.00 24.43 ? 10  GLY H C    1 
ATOM   1680 O O    . GLY B 2 10  ? 0.605   39.545 8.170   1.00 26.80 ? 10  GLY H O    1 
ATOM   1681 H H    . GLY B 2 10  ? 2.786   39.169 8.389   1.00 25.09 ? 10  GLY H H    1 
ATOM   1682 H HA2  . GLY B 2 10  ? 2.206   40.388 10.521  1.00 27.46 ? 10  GLY H HA2  1 
ATOM   1683 H HA3  . GLY B 2 10  ? 2.492   41.550 9.491   1.00 27.46 ? 10  GLY H HA3  1 
ATOM   1684 N N    . VAL B 2 11  ? -0.075  41.307 9.442   1.00 22.98 ? 11  VAL H N    1 
ATOM   1685 C CA   . VAL B 2 11  ? -1.451  41.296 8.963   1.00 21.92 ? 11  VAL H CA   1 
ATOM   1686 C C    . VAL B 2 11  ? -1.562  42.114 7.690   1.00 23.77 ? 11  VAL H C    1 
ATOM   1687 O O    . VAL B 2 11  ? -1.126  43.262 7.661   1.00 25.46 ? 11  VAL H O    1 
ATOM   1688 C CB   . VAL B 2 11  ? -2.411  41.820 10.040  1.00 23.96 ? 11  VAL H CB   1 
ATOM   1689 C CG1  . VAL B 2 11  ? -3.836  41.527 9.638   1.00 27.90 ? 11  VAL H CG1  1 
ATOM   1690 C CG2  . VAL B 2 11  ? -2.117  41.120 11.364  1.00 29.41 ? 11  VAL H CG2  1 
ATOM   1691 H H    . VAL B 2 11  ? 0.082   41.914 10.031  1.00 27.64 ? 11  VAL H H    1 
ATOM   1692 H HA   . VAL B 2 11  ? -1.694  40.382 8.746   1.00 26.37 ? 11  VAL H HA   1 
ATOM   1693 H HB   . VAL B 2 11  ? -2.294  42.778 10.142  1.00 28.82 ? 11  VAL H HB   1 
ATOM   1694 H HG11 . VAL B 2 11  ? -4.436  41.951 10.272  1.00 33.54 ? 11  VAL H HG11 1 
ATOM   1695 H HG12 . VAL B 2 11  ? -3.991  41.880 8.748   1.00 33.54 ? 11  VAL H HG12 1 
ATOM   1696 H HG13 . VAL B 2 11  ? -3.974  40.567 9.643   1.00 33.54 ? 11  VAL H HG13 1 
ATOM   1697 H HG21 . VAL B 2 11  ? -2.897  41.188 11.937  1.00 35.35 ? 11  VAL H HG21 1 
ATOM   1698 H HG22 . VAL B 2 11  ? -1.914  40.188 11.189  1.00 35.35 ? 11  VAL H HG22 1 
ATOM   1699 H HG23 . VAL B 2 11  ? -1.358  41.551 11.787  1.00 35.35 ? 11  VAL H HG23 1 
ATOM   1700 N N    . VAL B 2 12  ? -2.219  41.547 6.659   1.00 21.10 ? 12  VAL H N    1 
ATOM   1701 C CA   . VAL B 2 12  ? -2.440  42.237 5.388   1.00 22.91 ? 12  VAL H CA   1 
ATOM   1702 C C    . VAL B 2 12  ? -3.829  41.900 4.850   1.00 24.16 ? 12  VAL H C    1 
ATOM   1703 O O    . VAL B 2 12  ? -4.332  40.794 5.030   1.00 24.46 ? 12  VAL H O    1 
ATOM   1704 C CB   . VAL B 2 12  ? -1.360  41.862 4.353   1.00 31.37 ? 12  VAL H CB   1 
ATOM   1705 C CG1  . VAL B 2 12  ? -0.050  42.425 4.759   1.00 34.12 ? 12  VAL H CG1  1 
ATOM   1706 C CG2  . VAL B 2 12  ? -1.266  40.349 4.245   1.00 27.02 ? 12  VAL H CG2  1 
ATOM   1707 H H    . VAL B 2 12  ? -2.548  40.753 6.680   1.00 25.38 ? 12  VAL H H    1 
ATOM   1708 H HA   . VAL B 2 12  ? -2.414  43.194 5.544   1.00 27.56 ? 12  VAL H HA   1 
ATOM   1709 H HB   . VAL B 2 12  ? -1.597  42.228 3.487   1.00 37.70 ? 12  VAL H HB   1 
ATOM   1710 H HG11 . VAL B 2 12  ? 0.603   42.235 4.068   1.00 41.01 ? 12  VAL H HG11 1 
ATOM   1711 H HG12 . VAL B 2 12  ? -0.141  43.384 4.874   1.00 41.01 ? 12  VAL H HG12 1 
ATOM   1712 H HG13 . VAL B 2 12  ? 0.224   42.016 5.595   1.00 41.01 ? 12  VAL H HG13 1 
ATOM   1713 H HG21 . VAL B 2 12  ? -0.577  40.121 3.602   1.00 32.48 ? 12  VAL H HG21 1 
ATOM   1714 H HG22 . VAL B 2 12  ? -1.040  39.984 5.115   1.00 32.48 ? 12  VAL H HG22 1 
ATOM   1715 H HG23 . VAL B 2 12  ? -2.122  40.000 3.951   1.00 32.48 ? 12  VAL H HG23 1 
ATOM   1716 N N    . GLN B 2 13  ? -4.451  42.861 4.169   1.00 23.40 ? 13  GLN H N    1 
ATOM   1717 C CA   . GLN B 2 13  ? -5.778  42.585 3.644   1.00 27.16 ? 13  GLN H CA   1 
ATOM   1718 C C    . GLN B 2 13  ? -5.711  41.822 2.320   1.00 22.16 ? 13  GLN H C    1 
ATOM   1719 O O    . GLN B 2 13  ? -4.771  41.991 1.540   1.00 26.13 ? 13  GLN H O    1 
ATOM   1720 C CB   . GLN B 2 13  ? -6.571  43.880 3.427   1.00 33.72 ? 13  GLN H CB   1 
ATOM   1721 C CG   . GLN B 2 13  ? -6.656  44.828 4.616   1.00 35.65 ? 13  GLN H CG   1 
ATOM   1722 C CD   . GLN B 2 13  ? -8.101  45.099 5.031   1.00 45.61 ? 13  GLN H CD   1 
ATOM   1723 O OE1  . GLN B 2 13  ? -8.977  45.302 4.170   1.00 44.69 ? 13  GLN H OE1  1 
ATOM   1724 N NE2  . GLN B 2 13  ? -8.361  45.104 6.354   1.00 48.55 ? 13  GLN H NE2  1 
ATOM   1725 H H    . GLN B 2 13  ? -4.137  43.645 4.006   1.00 28.15 ? 13  GLN H H    1 
ATOM   1726 H HA   . GLN B 2 13  ? -6.250  42.038 4.291   1.00 32.65 ? 13  GLN H HA   1 
ATOM   1727 H HB2  . GLN B 2 13  ? -6.154  44.371 2.701   1.00 40.52 ? 13  GLN H HB2  1 
ATOM   1728 H HB3  . GLN B 2 13  ? -7.480  43.642 3.187   1.00 40.52 ? 13  GLN H HB3  1 
ATOM   1729 H HG2  . GLN B 2 13  ? -6.192  44.435 5.371   1.00 42.84 ? 13  GLN H HG2  1 
ATOM   1730 H HG3  . GLN B 2 13  ? -6.245  45.675 4.379   1.00 42.84 ? 13  GLN H HG3  1 
ATOM   1731 H HE21 . GLN B 2 13  ? -7.728  44.960 6.917   1.00 58.32 ? 13  GLN H HE21 1 
ATOM   1732 H HE22 . GLN B 2 13  ? -9.161  45.252 6.634   1.00 58.32 ? 13  GLN H HE22 1 
ATOM   1733 N N    . PRO B 2 14  ? -6.718  41.002 2.038   1.00 22.76 ? 14  PRO H N    1 
ATOM   1734 C CA   . PRO B 2 14  ? -6.752  40.303 0.756   1.00 23.15 ? 14  PRO H CA   1 
ATOM   1735 C C    . PRO B 2 14  ? -6.574  41.295 -0.373  1.00 28.17 ? 14  PRO H C    1 
ATOM   1736 O O    . PRO B 2 14  ? -7.054  42.432 -0.295  1.00 26.88 ? 14  PRO H O    1 
ATOM   1737 C CB   . PRO B 2 14  ? -8.136  39.661 0.739   1.00 28.79 ? 14  PRO H CB   1 
ATOM   1738 C CG   . PRO B 2 14  ? -8.502  39.520 2.174   1.00 25.19 ? 14  PRO H CG   1 
ATOM   1739 C CD   . PRO B 2 14  ? -7.909  40.704 2.849   1.00 24.12 ? 14  PRO H CD   1 
ATOM   1740 H HA   . PRO B 2 14  ? -6.079  39.606 0.706   1.00 27.84 ? 14  PRO H HA   1 
ATOM   1741 H HB2  . PRO B 2 14  ? -8.763  40.238 0.275   1.00 34.61 ? 14  PRO H HB2  1 
ATOM   1742 H HB3  . PRO B 2 14  ? -8.095  38.796 0.303   1.00 34.61 ? 14  PRO H HB3  1 
ATOM   1743 H HG2  . PRO B 2 14  ? -9.467  39.515 2.268   1.00 30.28 ? 14  PRO H HG2  1 
ATOM   1744 H HG3  . PRO B 2 14  ? -8.129  38.697 2.528   1.00 30.28 ? 14  PRO H HG3  1 
ATOM   1745 H HD2  . PRO B 2 14  ? -8.528  41.451 2.840   1.00 29.00 ? 14  PRO H HD2  1 
ATOM   1746 H HD3  . PRO B 2 14  ? -7.660  40.491 3.762   1.00 29.00 ? 14  PRO H HD3  1 
ATOM   1747 N N    . GLY B 2 15  ? -5.835  40.877 -1.401  1.00 29.28 ? 15  GLY H N    1 
ATOM   1748 C CA   . GLY B 2 15  ? -5.600  41.688 -2.566  1.00 29.04 ? 15  GLY H CA   1 
ATOM   1749 C C    . GLY B 2 15  ? -4.310  42.475 -2.537  1.00 26.10 ? 15  GLY H C    1 
ATOM   1750 O O    . GLY B 2 15  ? -3.826  42.875 -3.599  1.00 30.49 ? 15  GLY H O    1 
ATOM   1751 H H    . GLY B 2 15  ? -5.455  40.106 -1.435  1.00 35.20 ? 15  GLY H H    1 
ATOM   1752 H HA2  . GLY B 2 15  ? -5.578  41.112 -3.347  1.00 34.91 ? 15  GLY H HA2  1 
ATOM   1753 H HA3  . GLY B 2 15  ? -6.330  42.319 -2.659  1.00 34.91 ? 15  GLY H HA3  1 
ATOM   1754 N N    . ARG B 2 16  ? -3.732  42.695 -1.361  1.00 23.69 ? 16  ARG H N    1 
ATOM   1755 C CA   . ARG B 2 16  ? -2.527  43.482 -1.265  1.00 22.32 ? 16  ARG H CA   1 
ATOM   1756 C C    . ARG B 2 16  ? -1.277  42.594 -1.377  1.00 22.20 ? 16  ARG H C    1 
ATOM   1757 O O    . ARG B 2 16  ? -1.343  41.369 -1.569  1.00 23.92 ? 16  ARG H O    1 
ATOM   1758 C CB   . ARG B 2 16  ? -2.534  44.286 0.032   1.00 28.14 ? 16  ARG H CB   1 
ATOM   1759 H H    . ARG B 2 16  ? -4.024  42.395 -0.610  1.00 28.49 ? 16  ARG H H    1 
ATOM   1760 N N    . SER B 2 17  ? -0.132  43.250 -1.231  1.00 27.13 ? 17  SER H N    1 
ATOM   1761 C CA   . SER B 2 17  ? 1.180   42.661 -1.397  1.00 25.30 ? 17  SER H CA   1 
ATOM   1762 C C    . SER B 2 17  ? 1.966   42.762 -0.105  1.00 23.54 ? 17  SER H C    1 
ATOM   1763 O O    . SER B 2 17  ? 1.708   43.622 0.737   1.00 25.81 ? 17  SER H O    1 
ATOM   1764 C CB   . SER B 2 17  ? 1.949   43.354 -2.529  1.00 26.61 ? 17  SER H CB   1 
ATOM   1765 O OG   . SER B 2 17  ? 1.254   43.276 -3.766  1.00 28.66 ? 17  SER H OG   1 
ATOM   1766 H H    . SER B 2 17  ? -0.092  44.083 -1.024  1.00 32.62 ? 17  SER H H    1 
ATOM   1767 H HA   . SER B 2 17  ? 1.086   41.721 -1.617  1.00 30.42 ? 17  SER H HA   1 
ATOM   1768 H HB2  . SER B 2 17  ? 2.069   44.289 -2.298  1.00 31.99 ? 17  SER H HB2  1 
ATOM   1769 H HB3  . SER B 2 17  ? 2.812   42.923 -2.629  1.00 31.99 ? 17  SER H HB3  1 
ATOM   1770 H HG   . SER B 2 17  ? 1.760   42.964 -4.360  1.00 34.45 ? 17  SER H HG   1 
ATOM   1771 N N    . LEU B 2 18  ? 2.930   41.853 0.037   1.00 19.90 ? 18  LEU H N    1 
ATOM   1772 C CA   . LEU B 2 18  ? 3.832   41.778 1.177   1.00 21.09 ? 18  LEU H CA   1 
ATOM   1773 C C    . LEU B 2 18  ? 5.120   41.157 0.660   1.00 21.17 ? 18  LEU H C    1 
ATOM   1774 O O    . LEU B 2 18  ? 5.072   40.227 -0.152  1.00 23.14 ? 18  LEU H O    1 
ATOM   1775 C CB   . LEU B 2 18  ? 3.241   40.927 2.307   1.00 19.13 ? 18  LEU H CB   1 
ATOM   1776 C CG   . LEU B 2 18  ? 3.881   41.016 3.692   1.00 25.85 ? 18  LEU H CG   1 
ATOM   1777 C CD1  . LEU B 2 18  ? 3.783   42.450 4.251   1.00 30.92 ? 18  LEU H CD1  1 
ATOM   1778 C CD2  . LEU B 2 18  ? 3.199   39.990 4.640   1.00 23.82 ? 18  LEU H CD2  1 
ATOM   1779 H H    . LEU B 2 18  ? 3.087   41.239 -0.544  1.00 23.95 ? 18  LEU H H    1 
ATOM   1780 H HA   . LEU B 2 18  ? 4.010   42.658 1.545   1.00 25.37 ? 18  LEU H HA   1 
ATOM   1781 H HB2  . LEU B 2 18  ? 2.312   41.185 2.414   1.00 23.01 ? 18  LEU H HB2  1 
ATOM   1782 H HB3  . LEU B 2 18  ? 3.298   39.998 2.035   1.00 23.01 ? 18  LEU H HB3  1 
ATOM   1783 H HG   . LEU B 2 18  ? 4.825   40.800 3.633   1.00 31.09 ? 18  LEU H HG   1 
ATOM   1784 H HD11 . LEU B 2 18  ? 4.071   42.448 5.178   1.00 37.17 ? 18  LEU H HD11 1 
ATOM   1785 H HD12 . LEU B 2 18  ? 4.356   43.033 3.728   1.00 37.17 ? 18  LEU H HD12 1 
ATOM   1786 H HD13 . LEU B 2 18  ? 2.863   42.751 4.191   1.00 37.17 ? 18  LEU H HD13 1 
ATOM   1787 H HD21 . LEU B 2 18  ? 3.606   40.053 5.518   1.00 28.64 ? 18  LEU H HD21 1 
ATOM   1788 H HD22 . LEU B 2 18  ? 2.253   40.195 4.699   1.00 28.64 ? 18  LEU H HD22 1 
ATOM   1789 H HD23 . LEU B 2 18  ? 3.323   39.098 4.281   1.00 28.64 ? 18  LEU H HD23 1 
ATOM   1790 N N    . ARG B 2 19  ? 6.252   41.660 1.130   1.00 21.68 ? 19  ARG H N    1 
ATOM   1791 C CA   . ARG B 2 19  ? 7.561   41.126 0.785   1.00 19.49 ? 19  ARG H CA   1 
ATOM   1792 C C    . ARG B 2 19  ? 8.186   40.550 2.045   1.00 22.02 ? 19  ARG H C    1 
ATOM   1793 O O    . ARG B 2 19  ? 8.254   41.224 3.084   1.00 21.14 ? 19  ARG H O    1 
ATOM   1794 C CB   . ARG B 2 19  ? 8.488   42.193 0.170   1.00 21.11 ? 19  ARG H CB   1 
ATOM   1795 C CG   . ARG B 2 19  ? 9.800   41.601 -0.379  1.00 24.17 ? 19  ARG H CG   1 
ATOM   1796 C CD   . ARG B 2 19  ? 10.804  42.645 -0.916  1.00 30.74 ? 19  ARG H CD   1 
ATOM   1797 N NE   . ARG B 2 19  ? 11.598  43.181 0.182   1.00 40.45 ? 19  ARG H NE   1 
ATOM   1798 C CZ   . ARG B 2 19  ? 12.775  43.781 0.050   1.00 36.92 ? 19  ARG H CZ   1 
ATOM   1799 N NH1  . ARG B 2 19  ? 13.360  43.898 -1.124  1.00 39.39 ? 19  ARG H NH1  1 
ATOM   1800 N NH2  . ARG B 2 19  ? 13.390  44.258 1.134   1.00 40.22 ? 19  ARG H NH2  1 
ATOM   1801 H H    . ARG B 2 19  ? 6.289   42.330 1.668   1.00 26.07 ? 19  ARG H H    1 
ATOM   1802 H HA   . ARG B 2 19  ? 7.458   40.427 0.121   1.00 23.45 ? 19  ARG H HA   1 
ATOM   1803 H HB2  . ARG B 2 19  ? 8.025   42.628 -0.563  1.00 25.39 ? 19  ARG H HB2  1 
ATOM   1804 H HB3  . ARG B 2 19  ? 8.715   42.844 0.852   1.00 25.39 ? 19  ARG H HB3  1 
ATOM   1805 H HG2  . ARG B 2 19  ? 10.241  41.113 0.334   1.00 29.07 ? 19  ARG H HG2  1 
ATOM   1806 H HG3  . ARG B 2 19  ? 9.586   41.000 -1.110  1.00 29.07 ? 19  ARG H HG3  1 
ATOM   1807 H HD2  . ARG B 2 19  ? 11.400  42.226 -1.556  1.00 36.95 ? 19  ARG H HD2  1 
ATOM   1808 H HD3  . ARG B 2 19  ? 10.323  43.374 -1.338  1.00 36.95 ? 19  ARG H HD3  1 
ATOM   1809 H HE   . ARG B 2 19  ? 11.279  43.103 0.977   1.00 48.60 ? 19  ARG H HE   1 
ATOM   1810 H HH11 . ARG B 2 19  ? 12.979  43.583 -1.827  1.00 47.32 ? 19  ARG H HH11 1 
ATOM   1811 H HH12 . ARG B 2 19  ? 14.123  44.291 -1.187  1.00 47.32 ? 19  ARG H HH12 1 
ATOM   1812 H HH21 . ARG B 2 19  ? 13.024  44.176 1.907   1.00 48.32 ? 19  ARG H HH21 1 
ATOM   1813 H HH22 . ARG B 2 19  ? 14.153  44.648 1.058   1.00 48.32 ? 19  ARG H HH22 1 
ATOM   1814 N N    . LEU B 2 20  ? 8.587   39.285 1.969   1.00 17.81 ? 20  LEU H N    1 
ATOM   1815 C CA   . LEU B 2 20  ? 9.334   38.633 3.030   1.00 15.69 ? 20  LEU H CA   1 
ATOM   1816 C C    . LEU B 2 20  ? 10.811  38.597 2.679   1.00 17.47 ? 20  LEU H C    1 
ATOM   1817 O O    . LEU B 2 20  ? 11.182  38.570 1.505   1.00 18.92 ? 20  LEU H O    1 
ATOM   1818 C CB   . LEU B 2 20  ? 8.833   37.208 3.248   1.00 16.07 ? 20  LEU H CB   1 
ATOM   1819 C CG   . LEU B 2 20  ? 7.346   37.019 3.422   1.00 18.03 ? 20  LEU H CG   1 
ATOM   1820 C CD1  . LEU B 2 20  ? 7.064   35.560 3.696   1.00 17.11 ? 20  LEU H CD1  1 
ATOM   1821 C CD2  . LEU B 2 20  ? 6.805   37.851 4.613   1.00 21.42 ? 20  LEU H CD2  1 
ATOM   1822 H H    . LEU B 2 20  ? 8.433   38.774 1.295   1.00 21.43 ? 20  LEU H H    1 
ATOM   1823 H HA   . LEU B 2 20  ? 9.221   39.128 3.856   1.00 18.89 ? 20  LEU H HA   1 
ATOM   1824 H HB2  . LEU B 2 20  ? 9.096   36.679 2.479   1.00 19.34 ? 20  LEU H HB2  1 
ATOM   1825 H HB3  . LEU B 2 20  ? 9.257   36.862 4.049   1.00 19.34 ? 20  LEU H HB3  1 
ATOM   1826 H HG   . LEU B 2 20  ? 6.900   37.313 2.613   1.00 21.70 ? 20  LEU H HG   1 
ATOM   1827 H HD11 . LEU B 2 20  ? 6.116   35.450 3.870   1.00 20.60 ? 20  LEU H HD11 1 
ATOM   1828 H HD12 . LEU B 2 20  ? 7.321   35.038 2.920   1.00 20.60 ? 20  LEU H HD12 1 
ATOM   1829 H HD13 . LEU B 2 20  ? 7.577   35.279 4.469   1.00 20.60 ? 20  LEU H HD13 1 
ATOM   1830 H HD21 . LEU B 2 20  ? 5.865   37.647 4.739   1.00 25.77 ? 20  LEU H HD21 1 
ATOM   1831 H HD22 . LEU B 2 20  ? 7.303   37.620 5.412   1.00 25.77 ? 20  LEU H HD22 1 
ATOM   1832 H HD23 . LEU B 2 20  ? 6.915   38.794 4.415   1.00 25.77 ? 20  LEU H HD23 1 
ATOM   1833 N N    . SER B 2 21  ? 11.660  38.549 3.710   1.00 16.07 ? 21  SER H N    1 
ATOM   1834 C CA   . SER B 2 21  ? 13.098  38.518 3.580   1.00 18.75 ? 21  SER H CA   1 
ATOM   1835 C C    . SER B 2 21  ? 13.600  37.361 4.419   1.00 16.73 ? 21  SER H C    1 
ATOM   1836 O O    . SER B 2 21  ? 13.028  37.052 5.475   1.00 19.74 ? 21  SER H O    1 
ATOM   1837 C CB   . SER B 2 21  ? 13.717  39.831 4.092   1.00 22.11 ? 21  SER H CB   1 
ATOM   1838 O OG   . SER B 2 21  ? 13.369  40.852 3.193   1.00 28.75 ? 21  SER H OG   1 
ATOM   1839 H H    . SER B 2 21  ? 11.403  38.532 4.531   1.00 19.35 ? 21  SER H H    1 
ATOM   1840 H HA   . SER B 2 21  ? 13.367  38.397 2.656   1.00 22.56 ? 21  SER H HA   1 
ATOM   1841 H HB2  . SER B 2 21  ? 13.365  40.037 4.972   1.00 26.60 ? 21  SER H HB2  1 
ATOM   1842 H HB3  . SER B 2 21  ? 14.682  39.744 4.132   1.00 26.60 ? 21  SER H HB3  1 
ATOM   1843 H HG   . SER B 2 21  ? 13.716  41.578 3.435   1.00 34.56 ? 21  SER H HG   1 
ATOM   1844 N N    . CYS B 2 22  ? 14.635  36.701 3.918   1.00 16.05 ? 22  CYS H N    1 
ATOM   1845 C CA   . CYS B 2 22  ? 15.370  35.698 4.681   1.00 19.72 ? 22  CYS H CA   1 
ATOM   1846 C C    . CYS B 2 22  ? 16.863  35.993 4.634   1.00 18.89 ? 22  CYS H C    1 
ATOM   1847 O O    . CYS B 2 22  ? 17.472  35.979 3.559   1.00 18.86 ? 22  CYS H O    1 
ATOM   1848 C CB   . CYS B 2 22  ? 15.095  34.302 4.132   1.00 22.69 ? 22  CYS H CB   1 
ATOM   1849 S SG   . CYS B 2 22  ? 16.214  33.032 4.813   1.00 20.51 ? 22  CYS H SG   1 
ATOM   1850 H H    . CYS B 2 22  ? 14.938  36.819 3.122   1.00 19.33 ? 22  CYS H H    1 
ATOM   1851 H HA   . CYS B 2 22  ? 15.092  35.746 5.609   1.00 23.73 ? 22  CYS H HA   1 
ATOM   1852 H HB2  . CYS B 2 22  ? 14.186  34.050 4.356   1.00 27.29 ? 22  CYS H HB2  1 
ATOM   1853 H HB3  . CYS B 2 22  ? 15.209  34.314 3.169   1.00 27.29 ? 22  CYS H HB3  1 
ATOM   1854 N N    . ALA B 2 23  ? 17.453  36.259 5.795   1.00 19.65 ? 23  ALA H N    1 
ATOM   1855 C CA   . ALA B 2 23  ? 18.876  36.575 5.913   1.00 18.19 ? 23  ALA H CA   1 
ATOM   1856 C C    . ALA B 2 23  ? 19.643  35.297 6.187   1.00 20.76 ? 23  ALA H C    1 
ATOM   1857 O O    . ALA B 2 23  ? 19.373  34.628 7.192   1.00 23.94 ? 23  ALA H O    1 
ATOM   1858 C CB   . ALA B 2 23  ? 19.099  37.571 7.054   1.00 20.95 ? 23  ALA H CB   1 
ATOM   1859 H H    . ALA B 2 23  ? 17.041  36.263 6.550   1.00 23.65 ? 23  ALA H H    1 
ATOM   1860 H HA   . ALA B 2 23  ? 19.195  36.965 5.085   1.00 21.88 ? 23  ALA H HA   1 
ATOM   1861 H HB1  . ALA B 2 23  ? 20.051  37.727 7.154   1.00 25.20 ? 23  ALA H HB1  1 
ATOM   1862 H HB2  . ALA B 2 23  ? 18.648  38.402 6.840   1.00 25.20 ? 23  ALA H HB2  1 
ATOM   1863 H HB3  . ALA B 2 23  ? 18.736  37.199 7.873   1.00 25.20 ? 23  ALA H HB3  1 
ATOM   1864 N N    . ALA B 2 24  ? 20.584  34.957 5.307   1.00 16.84 ? 24  ALA H N    1 
ATOM   1865 C CA   . ALA B 2 24  ? 21.367  33.734 5.418   1.00 20.46 ? 24  ALA H CA   1 
ATOM   1866 C C    . ALA B 2 24  ? 22.759  34.043 5.954   1.00 20.31 ? 24  ALA H C    1 
ATOM   1867 O O    . ALA B 2 24  ? 23.414  34.977 5.488   1.00 23.14 ? 24  ALA H O    1 
ATOM   1868 C CB   . ALA B 2 24  ? 21.478  33.048 4.056   1.00 19.80 ? 24  ALA H CB   1 
ATOM   1869 H H    . ALA B 2 24  ? 20.790  35.432 4.621   1.00 20.27 ? 24  ALA H H    1 
ATOM   1870 H HA   . ALA B 2 24  ? 20.934  33.128 6.039   1.00 24.62 ? 24  ALA H HA   1 
ATOM   1871 H HB1  . ALA B 2 24  ? 22.041  32.263 4.143   1.00 23.82 ? 24  ALA H HB1  1 
ATOM   1872 H HB2  . ALA B 2 24  ? 20.591  32.788 3.761   1.00 23.82 ? 24  ALA H HB2  1 
ATOM   1873 H HB3  . ALA B 2 24  ? 21.869  33.668 3.421   1.00 23.82 ? 24  ALA H HB3  1 
ATOM   1874 N N    . SER B 2 25  ? 23.220  33.217 6.891   1.00 22.63 ? 25  SER H N    1 
ATOM   1875 C CA   . SER B 2 25  ? 24.534  33.349 7.493   1.00 26.48 ? 25  SER H CA   1 
ATOM   1876 C C    . SER B 2 25  ? 25.139  31.971 7.653   1.00 24.15 ? 25  SER H C    1 
ATOM   1877 O O    . SER B 2 25  ? 24.432  30.977 7.847   1.00 23.86 ? 25  SER H O    1 
ATOM   1878 C CB   . SER B 2 25  ? 24.449  33.987 8.896   1.00 26.83 ? 25  SER H CB   1 
ATOM   1879 O OG   . SER B 2 25  ? 24.010  35.339 8.819   1.00 38.34 ? 25  SER H OG   1 
ATOM   1880 H H    . SER B 2 25  ? 22.771  32.552 7.202   1.00 27.22 ? 25  SER H H    1 
ATOM   1881 H HA   . SER B 2 25  ? 25.094  33.894 6.917   1.00 31.83 ? 25  SER H HA   1 
ATOM   1882 H HB2  . SER B 2 25  ? 23.819  33.482 9.434   1.00 32.26 ? 25  SER H HB2  1 
ATOM   1883 H HB3  . SER B 2 25  ? 25.328  33.965 9.306   1.00 32.26 ? 25  SER H HB3  1 
ATOM   1884 H HG   . SER B 2 25  ? 23.912  35.654 9.592   1.00 46.07 ? 25  SER H HG   1 
ATOM   1885 N N    . GLY B 2 26  ? 26.459  31.932 7.676   1.00 24.95 ? 26  GLY H N    1 
ATOM   1886 C CA   . GLY B 2 26  ? 27.145  30.745 8.107   1.00 22.71 ? 26  GLY H CA   1 
ATOM   1887 C C    . GLY B 2 26  ? 27.397  29.717 7.043   1.00 20.99 ? 26  GLY H C    1 
ATOM   1888 O O    . GLY B 2 26  ? 27.789  28.593 7.383   1.00 24.84 ? 26  GLY H O    1 
ATOM   1889 H H    . GLY B 2 26  ? 26.973  32.582 7.445   1.00 30.00 ? 26  GLY H H    1 
ATOM   1890 H HA2  . GLY B 2 26  ? 28.006  31.004 8.473   1.00 27.32 ? 26  GLY H HA2  1 
ATOM   1891 H HA3  . GLY B 2 26  ? 26.620  30.322 8.804   1.00 27.32 ? 26  GLY H HA3  1 
ATOM   1892 N N    . PHE B 2 27  ? 27.155  30.052 5.777   1.00 20.47 ? 27  PHE H N    1 
ATOM   1893 C CA   . PHE B 2 27  ? 27.458  29.197 4.641   1.00 24.11 ? 27  PHE H CA   1 
ATOM   1894 C C    . PHE B 2 27  ? 27.615  30.077 3.407   1.00 18.41 ? 27  PHE H C    1 
ATOM   1895 O O    . PHE B 2 27  ? 27.299  31.273 3.421   1.00 20.45 ? 27  PHE H O    1 
ATOM   1896 C CB   . PHE B 2 27  ? 26.366  28.131 4.439   1.00 22.65 ? 27  PHE H CB   1 
ATOM   1897 C CG   . PHE B 2 27  ? 24.996  28.684 4.183   1.00 19.07 ? 27  PHE H CG   1 
ATOM   1898 C CD1  . PHE B 2 27  ? 24.160  29.091 5.224   1.00 22.06 ? 27  PHE H CD1  1 
ATOM   1899 C CD2  . PHE B 2 27  ? 24.484  28.662 2.889   1.00 21.11 ? 27  PHE H CD2  1 
ATOM   1900 C CE1  . PHE B 2 27  ? 22.870  29.565 4.948   1.00 20.11 ? 27  PHE H CE1  1 
ATOM   1901 C CE2  . PHE B 2 27  ? 23.172  29.136 2.622   1.00 19.14 ? 27  PHE H CE2  1 
ATOM   1902 C CZ   . PHE B 2 27  ? 22.393  29.555 3.626   1.00 13.56 ? 27  PHE H CZ   1 
ATOM   1903 H H    . PHE B 2 27  ? 26.802  30.801 5.544   1.00 24.62 ? 27  PHE H H    1 
ATOM   1904 H HA   . PHE B 2 27  ? 28.299  28.739 4.793   1.00 29.00 ? 27  PHE H HA   1 
ATOM   1905 H HB2  . PHE B 2 27  ? 26.608  27.582 3.676   1.00 27.24 ? 27  PHE H HB2  1 
ATOM   1906 H HB3  . PHE B 2 27  ? 26.316  27.584 5.239   1.00 27.24 ? 27  PHE H HB3  1 
ATOM   1907 H HD1  . PHE B 2 27  ? 24.460  29.048 6.103   1.00 26.53 ? 27  PHE H HD1  1 
ATOM   1908 H HD2  . PHE B 2 27  ? 25.006  28.334 2.193   1.00 25.39 ? 27  PHE H HD2  1 
ATOM   1909 H HE1  . PHE B 2 27  ? 22.332  29.885 5.636   1.00 24.19 ? 27  PHE H HE1  1 
ATOM   1910 H HE2  . PHE B 2 27  ? 22.854  29.155 1.748   1.00 23.03 ? 27  PHE H HE2  1 
ATOM   1911 H HZ   . PHE B 2 27  ? 21.526  29.843 3.447   1.00 16.33 ? 27  PHE H HZ   1 
ATOM   1912 N N    . THR B 2 28  ? 28.137  29.476 2.352   1.00 20.56 ? 28  THR H N    1 
ATOM   1913 C CA   . THR B 2 28  ? 28.316  30.169 1.084   1.00 19.44 ? 28  THR H CA   1 
ATOM   1914 C C    . THR B 2 28  ? 26.966  30.160 0.377   1.00 20.58 ? 28  THR H C    1 
ATOM   1915 O O    . THR B 2 28  ? 26.648  29.235 -0.358  1.00 19.55 ? 28  THR H O    1 
ATOM   1916 C CB   . THR B 2 28  ? 29.415  29.497 0.272   1.00 23.53 ? 28  THR H CB   1 
ATOM   1917 O OG1  . THR B 2 28  ? 30.567  29.273 1.130   1.00 22.72 ? 28  THR H OG1  1 
ATOM   1918 C CG2  . THR B 2 28  ? 29.803  30.353 -0.948  1.00 24.42 ? 28  THR H CG2  1 
ATOM   1919 H H    . THR B 2 28  ? 28.399  28.657 2.343   1.00 24.73 ? 28  THR H H    1 
ATOM   1920 H HA   . THR B 2 28  ? 28.580  31.092 1.223   1.00 23.39 ? 28  THR H HA   1 
ATOM   1921 H HB   . THR B 2 28  ? 29.103  28.645 -0.069  1.00 28.30 ? 28  THR H HB   1 
ATOM   1922 H HG1  . THR B 2 28  ? 31.192  28.927 0.688   1.00 27.32 ? 28  THR H HG1  1 
ATOM   1923 H HG21 . THR B 2 28  ? 30.480  29.897 -1.472  1.00 29.36 ? 28  THR H HG21 1 
ATOM   1924 H HG22 . THR B 2 28  ? 29.025  30.509 -1.505  1.00 29.36 ? 28  THR H HG22 1 
ATOM   1925 H HG23 . THR B 2 28  ? 30.156  31.208 -0.654  1.00 29.36 ? 28  THR H HG23 1 
ATOM   1926 N N    . PHE B 2 29  ? 26.189  31.226 0.594   1.00 19.68 ? 29  PHE H N    1 
ATOM   1927 C CA   . PHE B 2 29  ? 24.792  31.285 0.151   1.00 21.11 ? 29  PHE H CA   1 
ATOM   1928 C C    . PHE B 2 29  ? 24.621  30.960 -1.334  1.00 20.45 ? 29  PHE H C    1 
ATOM   1929 O O    . PHE B 2 29  ? 23.707  30.227 -1.719  1.00 15.24 ? 29  PHE H O    1 
ATOM   1930 C CB   . PHE B 2 29  ? 24.294  32.687 0.484   1.00 20.99 ? 29  PHE H CB   1 
ATOM   1931 C CG   . PHE B 2 29  ? 22.857  32.969 0.151   1.00 19.14 ? 29  PHE H CG   1 
ATOM   1932 C CD1  . PHE B 2 29  ? 21.808  32.389 0.849   1.00 16.64 ? 29  PHE H CD1  1 
ATOM   1933 C CD2  . PHE B 2 29  ? 22.568  33.933 -0.792  1.00 15.39 ? 29  PHE H CD2  1 
ATOM   1934 C CE1  . PHE B 2 29  ? 20.523  32.733 0.554   1.00 16.38 ? 29  PHE H CE1  1 
ATOM   1935 C CE2  . PHE B 2 29  ? 21.272  34.302 -1.069  1.00 16.50 ? 29  PHE H CE2  1 
ATOM   1936 C CZ   . PHE B 2 29  ? 20.250  33.709 -0.426  1.00 17.90 ? 29  PHE H CZ   1 
ATOM   1937 H H    . PHE B 2 29  ? 26.449  31.938 1.000   1.00 23.68 ? 29  PHE H H    1 
ATOM   1938 H HA   . PHE B 2 29  ? 24.259  30.619 0.613   1.00 25.40 ? 29  PHE H HA   1 
ATOM   1939 H HB2  . PHE B 2 29  ? 24.400  32.827 1.438   1.00 25.25 ? 29  PHE H HB2  1 
ATOM   1940 H HB3  . PHE B 2 29  ? 24.833  33.326 -0.007  1.00 25.25 ? 29  PHE H HB3  1 
ATOM   1941 H HD1  . PHE B 2 29  ? 21.982  31.766 1.517   1.00 20.03 ? 29  PHE H HD1  1 
ATOM   1942 H HD2  . PHE B 2 29  ? 23.266  34.343 -1.252  1.00 18.53 ? 29  PHE H HD2  1 
ATOM   1943 H HE1  . PHE B 2 29  ? 19.820  32.321 1.002   1.00 19.71 ? 29  PHE H HE1  1 
ATOM   1944 H HE2  . PHE B 2 29  ? 21.102  34.963 -1.701  1.00 19.86 ? 29  PHE H HE2  1 
ATOM   1945 H HZ   . PHE B 2 29  ? 19.372  33.940 -0.626  1.00 21.54 ? 29  PHE H HZ   1 
ATOM   1946 N N    . SER B 2 30  ? 25.475  31.500 -2.181  1.00 16.70 ? 30  SER H N    1 
ATOM   1947 C CA   . SER B 2 30  ? 25.399  31.274 -3.637  1.00 16.80 ? 30  SER H CA   1 
ATOM   1948 C C    . SER B 2 30  ? 25.586  29.820 -4.085  1.00 17.19 ? 30  SER H C    1 
ATOM   1949 O O    . SER B 2 30  ? 25.366  29.515 -5.266  1.00 18.71 ? 30  SER H O    1 
ATOM   1950 C CB   . SER B 2 30  ? 26.411  32.257 -4.254  1.00 21.58 ? 30  SER H CB   1 
ATOM   1951 O OG   . SER B 2 30  ? 27.700  31.673 -4.232  1.00 24.39 ? 30  SER H OG   1 
ATOM   1952 H H    . SER B 2 30  ? 26.125  32.013 -1.948  1.00 20.10 ? 30  SER H H    1 
ATOM   1953 H HA   . SER B 2 30  ? 24.513  31.466 -3.983  1.00 20.22 ? 30  SER H HA   1 
ATOM   1954 H HB2  . SER B 2 30  ? 26.158  32.446 -5.171  1.00 25.95 ? 30  SER H HB2  1 
ATOM   1955 H HB3  . SER B 2 30  ? 26.420  33.077 -3.737  1.00 25.95 ? 30  SER H HB3  1 
ATOM   1956 H HG   . SER B 2 30  ? 28.254  32.188 -4.597  1.00 29.32 ? 30  SER H HG   1 
ATOM   1957 N N    . LYS B 2 31  ? 25.991  28.912 -3.199  1.00 14.97 ? 31  LYS H N    1 
ATOM   1958 C CA   . LYS B 2 31  ? 26.209  27.534 -3.602  1.00 17.31 ? 31  LYS H CA   1 
ATOM   1959 C C    . LYS B 2 31  ? 25.031  26.647 -3.260  1.00 14.16 ? 31  LYS H C    1 
ATOM   1960 O O    . LYS B 2 31  ? 25.161  25.428 -3.373  1.00 11.82 ? 31  LYS H O    1 
ATOM   1961 C CB   . LYS B 2 31  ? 27.497  26.986 -2.985  1.00 17.35 ? 31  LYS H CB   1 
ATOM   1962 C CG   . LYS B 2 31  ? 28.756  27.745 -3.367  1.00 24.34 ? 31  LYS H CG   1 
ATOM   1963 C CD   . LYS B 2 31  ? 29.965  26.888 -3.046  1.00 24.26 ? 31  LYS H CD   1 
ATOM   1964 C CE   . LYS B 2 31  ? 31.266  27.494 -3.561  1.00 29.55 ? 31  LYS H CE   1 
ATOM   1965 N NZ   . LYS B 2 31  ? 31.552  27.081 -4.964  1.00 30.22 ? 31  LYS H NZ   1 
ATOM   1966 H H    . LYS B 2 31  ? 26.144  29.074 -2.368  1.00 18.03 ? 31  LYS H H    1 
ATOM   1967 H HA   . LYS B 2 31  ? 26.329  27.507 -4.564  1.00 20.83 ? 31  LYS H HA   1 
ATOM   1968 H HB2  . LYS B 2 31  ? 27.416  27.022 -2.019  1.00 20.89 ? 31  LYS H HB2  1 
ATOM   1969 H HB3  . LYS B 2 31  ? 27.611  26.067 -3.274  1.00 20.89 ? 31  LYS H HB3  1 
ATOM   1970 H HG2  . LYS B 2 31  ? 28.750  27.938 -4.318  1.00 29.27 ? 31  LYS H HG2  1 
ATOM   1971 H HG3  . LYS B 2 31  ? 28.811  28.570 -2.861  1.00 29.27 ? 31  LYS H HG3  1 
ATOM   1972 H HD2  . LYS B 2 31  ? 30.039  26.792 -2.083  1.00 29.17 ? 31  LYS H HD2  1 
ATOM   1973 H HD3  . LYS B 2 31  ? 29.855  26.017 -3.459  1.00 29.17 ? 31  LYS H HD3  1 
ATOM   1974 H HE2  . LYS B 2 31  ? 31.200  28.461 -3.536  1.00 35.52 ? 31  LYS H HE2  1 
ATOM   1975 H HE3  . LYS B 2 31  ? 32.000  27.197 -3.001  1.00 35.52 ? 31  LYS H HE3  1 
ATOM   1976 H HZ1  . LYS B 2 31  ? 32.251  27.533 -5.278  1.00 36.32 ? 31  LYS H HZ1  1 
ATOM   1977 H HZ2  . LYS B 2 31  ? 31.733  26.210 -4.994  1.00 36.32 ? 31  LYS H HZ2  1 
ATOM   1978 H HZ3  . LYS B 2 31  ? 30.845  27.246 -5.480  1.00 36.32 ? 31  LYS H HZ3  1 
ATOM   1979 N N    . TYR B 2 32  ? 23.870  27.217 -2.931  1.00 13.85 ? 32  TYR H N    1 
ATOM   1980 C CA   . TYR B 2 32  ? 22.707  26.431 -2.547  1.00 14.20 ? 32  TYR H CA   1 
ATOM   1981 C C    . TYR B 2 32  ? 21.412  26.930 -3.172  1.00 15.07 ? 32  TYR H C    1 
ATOM   1982 O O    . TYR B 2 32  ? 21.145  28.139 -3.238  1.00 14.48 ? 32  TYR H O    1 
ATOM   1983 C CB   . TYR B 2 32  ? 22.552  26.500 -1.040  1.00 13.76 ? 32  TYR H CB   1 
ATOM   1984 C CG   . TYR B 2 32  ? 23.724  25.925 -0.249  1.00 13.30 ? 32  TYR H CG   1 
ATOM   1985 C CD1  . TYR B 2 32  ? 23.797  24.581 0.117   1.00 17.43 ? 32  TYR H CD1  1 
ATOM   1986 C CD2  . TYR B 2 32  ? 24.803  26.734 0.032   1.00 16.17 ? 32  TYR H CD2  1 
ATOM   1987 C CE1  . TYR B 2 32  ? 24.902  24.081 0.824   1.00 17.80 ? 32  TYR H CE1  1 
ATOM   1988 C CE2  . TYR B 2 32  ? 25.900  26.257 0.716   1.00 17.48 ? 32  TYR H CE2  1 
ATOM   1989 C CZ   . TYR B 2 32  ? 25.973  24.949 1.136   1.00 21.27 ? 32  TYR H CZ   1 
ATOM   1990 O OH   . TYR B 2 32  ? 27.128  24.517 1.825   1.00 18.03 ? 32  TYR H OH   1 
ATOM   1991 H H    . TYR B 2 32  ? 23.734  28.066 -2.925  1.00 16.68 ? 32  TYR H H    1 
ATOM   1992 H HA   . TYR B 2 32  ? 22.833  25.526 -2.872  1.00 17.10 ? 32  TYR H HA   1 
ATOM   1993 H HB2  . TYR B 2 32  ? 22.454  27.430 -0.783  1.00 16.57 ? 32  TYR H HB2  1 
ATOM   1994 H HB3  . TYR B 2 32  ? 21.758  26.002 -0.790  1.00 16.57 ? 32  TYR H HB3  1 
ATOM   1995 H HD1  . TYR B 2 32  ? 23.102  24.007 -0.111  1.00 20.98 ? 32  TYR H HD1  1 
ATOM   1996 H HD2  . TYR B 2 32  ? 24.791  27.622 -0.246  1.00 19.46 ? 32  TYR H HD2  1 
ATOM   1997 H HE1  . TYR B 2 32  ? 24.929  23.188 1.083   1.00 21.42 ? 32  TYR H HE1  1 
ATOM   1998 H HE2  . TYR B 2 32  ? 26.607  26.833 0.898   1.00 21.04 ? 32  TYR H HE2  1 
ATOM   1999 H HH   . TYR B 2 32  ? 27.459  25.155 2.260   1.00 21.70 ? 32  TYR H HH   1 
ATOM   2000 N N    . VAL B 2 33  ? 20.562  25.980 -3.551  1.00 12.93 ? 33  VAL H N    1 
ATOM   2001 C CA   . VAL B 2 33  ? 19.187  26.269 -3.895  1.00 11.20 ? 33  VAL H CA   1 
ATOM   2002 C C    . VAL B 2 33  ? 18.417  26.666 -2.643  1.00 11.46 ? 33  VAL H C    1 
ATOM   2003 O O    . VAL B 2 33  ? 18.592  26.035 -1.592  1.00 11.53 ? 33  VAL H O    1 
ATOM   2004 C CB   . VAL B 2 33  ? 18.594  25.012 -4.556  1.00 10.09 ? 33  VAL H CB   1 
ATOM   2005 C CG1  . VAL B 2 33  ? 17.107  25.223 -4.828  1.00 11.18 ? 33  VAL H CG1  1 
ATOM   2006 C CG2  . VAL B 2 33  ? 19.360  24.658 -5.836  1.00 11.98 ? 33  VAL H CG2  1 
ATOM   2007 H H    . VAL B 2 33  ? 20.766  25.147 -3.617  1.00 15.57 ? 33  VAL H H    1 
ATOM   2008 H HA   . VAL B 2 33  ? 19.133  27.017 -4.511  1.00 13.50 ? 33  VAL H HA   1 
ATOM   2009 H HB   . VAL B 2 33  ? 18.684  24.257 -3.954  1.00 12.17 ? 33  VAL H HB   1 
ATOM   2010 H HG11 . VAL B 2 33  ? 16.792  24.525 -5.423  1.00 13.48 ? 33  VAL H HG11 1 
ATOM   2011 H HG12 . VAL B 2 33  ? 16.623  25.184 -3.988  1.00 13.48 ? 33  VAL H HG12 1 
ATOM   2012 H HG13 . VAL B 2 33  ? 16.981  26.092 -5.241  1.00 13.48 ? 33  VAL H HG13 1 
ATOM   2013 H HG21 . VAL B 2 33  ? 18.872  23.971 -6.316  1.00 14.44 ? 33  VAL H HG21 1 
ATOM   2014 H HG22 . VAL B 2 33  ? 19.441  25.452 -6.387  1.00 14.44 ? 33  VAL H HG22 1 
ATOM   2015 H HG23 . VAL B 2 33  ? 20.242  24.331 -5.597  1.00 14.44 ? 33  VAL H HG23 1 
ATOM   2016 N N    . MET B 2 34  ? 17.584  27.719 -2.719  1.00 11.94 ? 34  MET H N    1 
ATOM   2017 C CA   . MET B 2 34  ? 16.882  28.179 -1.517  1.00 13.46 ? 34  MET H CA   1 
ATOM   2018 C C    . MET B 2 34  ? 15.383  28.113 -1.782  1.00 11.59 ? 34  MET H C    1 
ATOM   2019 O O    . MET B 2 34  ? 14.940  28.205 -2.939  1.00 11.08 ? 34  MET H O    1 
ATOM   2020 C CB   . MET B 2 34  ? 17.254  29.591 -1.156  1.00 11.88 ? 34  MET H CB   1 
ATOM   2021 C CG   . MET B 2 34  ? 18.730  29.554 -0.936  1.00 11.84 ? 34  MET H CG   1 
ATOM   2022 S SD   . MET B 2 34  ? 19.276  28.911 0.633   1.00 14.31 ? 34  MET H SD   1 
ATOM   2023 C CE   . MET B 2 34  ? 18.178  29.530 1.777   1.00 13.86 ? 34  MET H CE   1 
ATOM   2024 H H    . MET B 2 34  ? 17.419  28.166 -3.434  1.00 14.39 ? 34  MET H H    1 
ATOM   2025 H HA   . MET B 2 34  ? 17.122  27.613 -0.767  1.00 16.21 ? 34  MET H HA   1 
ATOM   2026 H HB2  . MET B 2 34  ? 17.040  30.200 -1.881  1.00 14.32 ? 34  MET H HB2  1 
ATOM   2027 H HB3  . MET B 2 34  ? 16.803  29.870 -0.344  1.00 14.32 ? 34  MET H HB3  1 
ATOM   2028 H HG2  . MET B 2 34  ? 19.125  28.998 -1.625  1.00 14.27 ? 34  MET H HG2  1 
ATOM   2029 H HG3  . MET B 2 34  ? 19.069  30.460 -1.006  1.00 14.27 ? 34  MET H HG3  1 
ATOM   2030 H HE1  . MET B 2 34  ? 18.440  29.228 2.661   1.00 16.69 ? 34  MET H HE1  1 
ATOM   2031 H HE2  . MET B 2 34  ? 18.195  30.499 1.740   1.00 16.69 ? 34  MET H HE2  1 
ATOM   2032 H HE3  . MET B 2 34  ? 17.288  29.207 1.568   1.00 16.69 ? 34  MET H HE3  1 
ATOM   2033 N N    . HIS B 2 35  ? 14.588  27.949 -0.724  1.00 10.58 ? 35  HIS H N    1 
ATOM   2034 C CA   . HIS B 2 35  ? 13.156  27.794 -0.847  1.00 11.92 ? 35  HIS H CA   1 
ATOM   2035 C C    . HIS B 2 35  ? 12.400  28.593 0.195   1.00 12.90 ? 35  HIS H C    1 
ATOM   2036 O O    . HIS B 2 35  ? 12.907  28.868 1.295   1.00 12.70 ? 35  HIS H O    1 
ATOM   2037 C CB   . HIS B 2 35  ? 12.724  26.336 -0.642  1.00 9.55  ? 35  HIS H CB   1 
ATOM   2038 C CG   . HIS B 2 35  ? 13.382  25.372 -1.560  1.00 13.04 ? 35  HIS H CG   1 
ATOM   2039 N ND1  . HIS B 2 35  ? 12.838  25.037 -2.781  1.00 12.34 ? 35  HIS H ND1  1 
ATOM   2040 C CD2  . HIS B 2 35  ? 14.532  24.673 -1.447  1.00 11.66 ? 35  HIS H CD2  1 
ATOM   2041 C CE1  . HIS B 2 35  ? 13.618  24.153 -3.375  1.00 13.99 ? 35  HIS H CE1  1 
ATOM   2042 N NE2  . HIS B 2 35  ? 14.673  23.945 -2.603  1.00 12.34 ? 35  HIS H NE2  1 
ATOM   2043 H H    . HIS B 2 35  ? 14.868  27.924 0.089   1.00 12.76 ? 35  HIS H H    1 
ATOM   2044 H HA   . HIS B 2 35  ? 12.931  28.125 -1.731  1.00 14.36 ? 35  HIS H HA   1 
ATOM   2045 H HB2  . HIS B 2 35  ? 12.940  26.073 0.266   1.00 11.53 ? 35  HIS H HB2  1 
ATOM   2046 H HB3  . HIS B 2 35  ? 11.766  26.274 -0.786  1.00 11.53 ? 35  HIS H HB3  1 
ATOM   2047 H HD2  . HIS B 2 35  ? 15.117  24.682 -0.725  1.00 14.05 ? 35  HIS H HD2  1 
ATOM   2048 H HE1  . HIS B 2 35  ? 13.455  23.746 -4.195  1.00 16.85 ? 35  HIS H HE1  1 
ATOM   2049 H HE2  . HIS B 2 35  ? 15.339  23.436 -2.795  1.00 14.87 ? 35  HIS H HE2  1 
ATOM   2050 N N    . TRP B 2 36  ? 11.134  28.794 -0.121  1.00 11.96 ? 36  TRP H N    1 
ATOM   2051 C CA   . TRP B 2 36  ? 10.103  29.132 0.844   1.00 13.30 ? 36  TRP H CA   1 
ATOM   2052 C C    . TRP B 2 36  ? 9.167   27.938 0.935   1.00 12.24 ? 36  TRP H C    1 
ATOM   2053 O O    . TRP B 2 36  ? 8.679   27.423 -0.088  1.00 12.37 ? 36  TRP H O    1 
ATOM   2054 C CB   . TRP B 2 36  ? 9.351   30.384 0.416   1.00 13.63 ? 36  TRP H CB   1 
ATOM   2055 C CG   . TRP B 2 36  ? 10.197  31.641 0.474   1.00 13.68 ? 36  TRP H CG   1 
ATOM   2056 C CD1  . TRP B 2 36  ? 10.864  32.229 -0.574  1.00 14.17 ? 36  TRP H CD1  1 
ATOM   2057 C CD2  . TRP B 2 36  ? 10.468  32.451 1.611   1.00 14.50 ? 36  TRP H CD2  1 
ATOM   2058 N NE1  . TRP B 2 36  ? 11.524  33.356 -0.153  1.00 13.91 ? 36  TRP H NE1  1 
ATOM   2059 C CE2  . TRP B 2 36  ? 11.287  33.512 1.183   1.00 16.23 ? 36  TRP H CE2  1 
ATOM   2060 C CE3  . TRP B 2 36  ? 10.102  32.388 2.952   1.00 14.83 ? 36  TRP H CE3  1 
ATOM   2061 C CZ2  . TRP B 2 36  ? 11.751  34.495 2.051   1.00 17.07 ? 36  TRP H CZ2  1 
ATOM   2062 C CZ3  . TRP B 2 36  ? 10.587  33.381 3.825   1.00 15.83 ? 36  TRP H CZ3  1 
ATOM   2063 C CH2  . TRP B 2 36  ? 11.362  34.430 3.352   1.00 17.08 ? 36  TRP H CH2  1 
ATOM   2064 H H    . TRP B 2 36  ? 10.834  28.738 -0.925  1.00 14.42 ? 36  TRP H H    1 
ATOM   2065 H HA   . TRP B 2 36  ? 10.483  29.311 1.718   1.00 16.02 ? 36  TRP H HA   1 
ATOM   2066 H HB2  . TRP B 2 36  ? 9.048   30.270 -0.498  1.00 16.41 ? 36  TRP H HB2  1 
ATOM   2067 H HB3  . TRP B 2 36  ? 8.590   30.509 1.005   1.00 16.41 ? 36  TRP H HB3  1 
ATOM   2068 H HD1  . TRP B 2 36  ? 10.867  31.908 -1.447  1.00 17.06 ? 36  TRP H HD1  1 
ATOM   2069 H HE1  . TRP B 2 36  ? 12.004  33.874 -0.645  1.00 16.75 ? 36  TRP H HE1  1 
ATOM   2070 H HE3  . TRP B 2 36  ? 9.551   31.708 3.264   1.00 17.86 ? 36  TRP H HE3  1 
ATOM   2071 H HZ2  . TRP B 2 36  ? 12.310  35.176 1.750   1.00 20.54 ? 36  TRP H HZ2  1 
ATOM   2072 H HZ3  . TRP B 2 36  ? 10.386  33.332 4.732   1.00 19.05 ? 36  TRP H HZ3  1 
ATOM   2073 H HH2  . TRP B 2 36  ? 11.622  35.104 3.938   1.00 20.56 ? 36  TRP H HH2  1 
ATOM   2074 N N    . VAL B 2 37  ? 8.838   27.596 2.171   1.00 10.55 ? 37  VAL H N    1 
ATOM   2075 C CA   . VAL B 2 37  ? 7.880   26.574 2.545   1.00 10.13 ? 37  VAL H CA   1 
ATOM   2076 C C    . VAL B 2 37  ? 6.933   27.185 3.556   1.00 11.76 ? 37  VAL H C    1 
ATOM   2077 O O    . VAL B 2 37  ? 7.371   27.889 4.463   1.00 13.94 ? 37  VAL H O    1 
ATOM   2078 C CB   . VAL B 2 37  ? 8.582   25.341 3.141   1.00 10.90 ? 37  VAL H CB   1 
ATOM   2079 C CG1  . VAL B 2 37  ? 7.554   24.213 3.450   1.00 13.77 ? 37  VAL H CG1  1 
ATOM   2080 C CG2  . VAL B 2 37  ? 9.643   24.816 2.222   1.00 15.43 ? 37  VAL H CG2  1 
ATOM   2081 H H    . VAL B 2 37  ? 9.185   27.972 2.862   1.00 12.72 ? 37  VAL H H    1 
ATOM   2082 H HA   . VAL B 2 37  ? 7.374   26.290 1.768   1.00 12.22 ? 37  VAL H HA   1 
ATOM   2083 H HB   . VAL B 2 37  ? 9.005   25.617 3.969   1.00 13.15 ? 37  VAL H HB   1 
ATOM   2084 H HG11 . VAL B 2 37  ? 8.009   23.488 3.908   1.00 16.58 ? 37  VAL H HG11 1 
ATOM   2085 H HG12 . VAL B 2 37  ? 6.852   24.571 4.015   1.00 16.58 ? 37  VAL H HG12 1 
ATOM   2086 H HG13 . VAL B 2 37  ? 7.177   23.892 2.616   1.00 16.58 ? 37  VAL H HG13 1 
ATOM   2087 H HG21 . VAL B 2 37  ? 9.923   23.940 2.530   1.00 18.58 ? 37  VAL H HG21 1 
ATOM   2088 H HG22 . VAL B 2 37  ? 9.280   24.751 1.325   1.00 18.58 ? 37  VAL H HG22 1 
ATOM   2089 H HG23 . VAL B 2 37  ? 10.398  25.426 2.230   1.00 18.58 ? 37  VAL H HG23 1 
ATOM   2090 N N    . ARG B 2 38  ? 5.657   26.888 3.424   1.00 12.40 ? 38  ARG H N    1 
ATOM   2091 C CA   . ARG B 2 38  ? 4.678   27.459 4.337   1.00 11.78 ? 38  ARG H CA   1 
ATOM   2092 C C    . ARG B 2 38  ? 3.834   26.397 5.030   1.00 15.42 ? 38  ARG H C    1 
ATOM   2093 O O    . ARG B 2 38  ? 3.703   25.261 4.585   1.00 12.61 ? 38  ARG H O    1 
ATOM   2094 C CB   . ARG B 2 38  ? 3.792   28.489 3.607   1.00 14.05 ? 38  ARG H CB   1 
ATOM   2095 C CG   . ARG B 2 38  ? 2.827   27.877 2.701   1.00 13.23 ? 38  ARG H CG   1 
ATOM   2096 C CD   . ARG B 2 38  ? 1.958   28.951 2.031   1.00 16.39 ? 38  ARG H CD   1 
ATOM   2097 N NE   . ARG B 2 38  ? 1.055   28.382 1.028   1.00 16.62 ? 38  ARG H NE   1 
ATOM   2098 C CZ   . ARG B 2 38  ? 0.290   29.097 0.199   1.00 16.50 ? 38  ARG H CZ   1 
ATOM   2099 N NH1  . ARG B 2 38  ? 0.313   30.411 0.204   1.00 17.21 ? 38  ARG H NH1  1 
ATOM   2100 N NH2  . ARG B 2 38  ? -0.543  28.474 -0.639  1.00 20.15 ? 38  ARG H NH2  1 
ATOM   2101 H H    . ARG B 2 38  ? 5.333   26.366 2.822   1.00 14.94 ? 38  ARG H H    1 
ATOM   2102 H HA   . ARG B 2 38  ? 5.153   27.909 5.053   1.00 14.20 ? 38  ARG H HA   1 
ATOM   2103 H HB2  . ARG B 2 38  ? 3.298   29.002 4.266   1.00 16.92 ? 38  ARG H HB2  1 
ATOM   2104 H HB3  . ARG B 2 38  ? 4.359   29.078 3.086   1.00 16.92 ? 38  ARG H HB3  1 
ATOM   2105 H HG2  . ARG B 2 38  ? 3.298   27.386 2.009   1.00 15.94 ? 38  ARG H HG2  1 
ATOM   2106 H HG3  . ARG B 2 38  ? 2.249   27.278 3.198   1.00 15.94 ? 38  ARG H HG3  1 
ATOM   2107 H HD2  . ARG B 2 38  ? 1.420   29.393 2.707   1.00 19.73 ? 38  ARG H HD2  1 
ATOM   2108 H HD3  . ARG B 2 38  ? 2.532   29.597 1.590   1.00 19.73 ? 38  ARG H HD3  1 
ATOM   2109 H HE   . ARG B 2 38  ? 1.015   27.525 0.969   1.00 20.01 ? 38  ARG H HE   1 
ATOM   2110 H HH11 . ARG B 2 38  ? 0.829   30.830 0.750   1.00 20.71 ? 38  ARG H HH11 1 
ATOM   2111 H HH12 . ARG B 2 38  ? -0.188  30.853 -0.338  1.00 20.71 ? 38  ARG H HH12 1 
ATOM   2112 H HH21 . ARG B 2 38  ? -0.586  27.616 -0.644  1.00 24.24 ? 38  ARG H HH21 1 
ATOM   2113 H HH22 . ARG B 2 38  ? -1.037  28.932 -1.174  1.00 24.24 ? 38  ARG H HH22 1 
ATOM   2114 N N    . GLN B 2 39  ? 3.226   26.820 6.129   1.00 12.76 ? 39  GLN H N    1 
ATOM   2115 C CA   . GLN B 2 39  ? 2.405   25.944 6.957   1.00 12.92 ? 39  GLN H CA   1 
ATOM   2116 C C    . GLN B 2 39  ? 1.218   26.750 7.460   1.00 15.29 ? 39  GLN H C    1 
ATOM   2117 O O    . GLN B 2 39  ? 1.369   27.615 8.337   1.00 15.19 ? 39  GLN H O    1 
ATOM   2118 C CB   . GLN B 2 39  ? 3.213   25.387 8.120   1.00 13.74 ? 39  GLN H CB   1 
ATOM   2119 C CG   . GLN B 2 39  ? 2.509   24.402 9.010   1.00 16.59 ? 39  GLN H CG   1 
ATOM   2120 C CD   . GLN B 2 39  ? 3.492   23.671 9.858   1.00 19.36 ? 39  GLN H CD   1 
ATOM   2121 O OE1  . GLN B 2 39  ? 4.447   24.246 10.375  1.00 17.96 ? 39  GLN H OE1  1 
ATOM   2122 N NE2  . GLN B 2 39  ? 3.283   22.406 9.999   1.00 20.01 ? 39  GLN H NE2  1 
ATOM   2123 H H    . GLN B 2 39  ? 3.273   27.627 6.423   1.00 15.37 ? 39  GLN H H    1 
ATOM   2124 H HA   . GLN B 2 39  ? 2.072   25.204 6.426   1.00 15.57 ? 39  GLN H HA   1 
ATOM   2125 H HB2  . GLN B 2 39  ? 3.993   24.938 7.758   1.00 16.55 ? 39  GLN H HB2  1 
ATOM   2126 H HB3  . GLN B 2 39  ? 3.488   26.131 8.679   1.00 16.55 ? 39  GLN H HB3  1 
ATOM   2127 H HG2  . GLN B 2 39  ? 1.890   24.873 9.590   1.00 19.97 ? 39  GLN H HG2  1 
ATOM   2128 H HG3  . GLN B 2 39  ? 2.030   23.757 8.466   1.00 19.97 ? 39  GLN H HG3  1 
ATOM   2129 H HE21 . GLN B 2 39  ? 2.609   22.036 9.615   1.00 24.07 ? 39  GLN H HE21 1 
ATOM   2130 H HE22 . GLN B 2 39  ? 3.818   21.932 10.478  1.00 24.07 ? 39  GLN H HE22 1 
ATOM   2131 N N    . ALA B 2 40  ? 0.058   26.450 6.936   1.00 12.30 ? 40  ALA H N    1 
ATOM   2132 C CA   . ALA B 2 40  ? -1.164  27.104 7.379   1.00 17.75 ? 40  ALA H CA   1 
ATOM   2133 C C    . ALA B 2 40  ? -1.565  26.571 8.748   1.00 22.57 ? 40  ALA H C    1 
ATOM   2134 O O    . ALA B 2 40  ? -1.213  25.447 9.110   1.00 16.85 ? 40  ALA H O    1 
ATOM   2135 C CB   . ALA B 2 40  ? -2.287  26.856 6.383   1.00 17.90 ? 40  ALA H CB   1 
ATOM   2136 H H    . ALA B 2 40  ? -0.060  25.866 6.316   1.00 14.82 ? 40  ALA H H    1 
ATOM   2137 H HA   . ALA B 2 40  ? -1.020  28.061 7.443   1.00 21.36 ? 40  ALA H HA   1 
ATOM   2138 H HB1  . ALA B 2 40  ? -3.022  27.458 6.579   1.00 21.54 ? 40  ALA H HB1  1 
ATOM   2139 H HB2  . ALA B 2 40  ? -1.956  27.020 5.486   1.00 21.54 ? 40  ALA H HB2  1 
ATOM   2140 H HB3  . ALA B 2 40  ? -2.583  25.935 6.463   1.00 21.54 ? 40  ALA H HB3  1 
ATOM   2141 N N    . PRO B 2 41  ? -2.308  27.352 9.526   1.00 20.75 ? 41  PRO H N    1 
ATOM   2142 C CA   . PRO B 2 41  ? -2.672  26.910 10.875  1.00 22.12 ? 41  PRO H CA   1 
ATOM   2143 C C    . PRO B 2 41  ? -3.261  25.513 10.910  1.00 21.88 ? 41  PRO H C    1 
ATOM   2144 O O    . PRO B 2 41  ? -4.251  25.234 10.231  1.00 26.68 ? 41  PRO H O    1 
ATOM   2145 C CB   . PRO B 2 41  ? -3.718  27.951 11.302  1.00 26.10 ? 41  PRO H CB   1 
ATOM   2146 C CG   . PRO B 2 41  ? -3.310  29.202 10.548  1.00 31.00 ? 41  PRO H CG   1 
ATOM   2147 C CD   . PRO B 2 41  ? -2.877  28.678 9.213   1.00 24.17 ? 41  PRO H CD   1 
ATOM   2148 H HA   . PRO B 2 41  ? -1.896  26.945 11.456  1.00 26.60 ? 41  PRO H HA   1 
ATOM   2149 H HB2  . PRO B 2 41  ? -4.606  27.659 11.044  1.00 31.38 ? 41  PRO H HB2  1 
ATOM   2150 H HB3  . PRO B 2 41  ? -3.680  28.091 12.261  1.00 31.38 ? 41  PRO H HB3  1 
ATOM   2151 H HG2  . PRO B 2 41  ? -4.065  29.805 10.462  1.00 37.26 ? 41  PRO H HG2  1 
ATOM   2152 H HG3  . PRO B 2 41  ? -2.580  29.648 11.005  1.00 37.26 ? 41  PRO H HG3  1 
ATOM   2153 H HD2  . PRO B 2 41  ? -3.635  28.594 8.614   1.00 29.07 ? 41  PRO H HD2  1 
ATOM   2154 H HD3  . PRO B 2 41  ? -2.205  29.255 8.819   1.00 29.07 ? 41  PRO H HD3  1 
ATOM   2155 N N    . GLY B 2 42  ? -2.680  24.645 11.728  1.00 25.96 ? 42  GLY H N    1 
ATOM   2156 C CA   . GLY B 2 42  ? -3.175  23.297 11.890  1.00 25.75 ? 42  GLY H CA   1 
ATOM   2157 C C    . GLY B 2 42  ? -2.951  22.366 10.727  1.00 26.28 ? 42  GLY H C    1 
ATOM   2158 O O    . GLY B 2 42  ? -3.438  21.225 10.770  1.00 28.22 ? 42  GLY H O    1 
ATOM   2159 H H    . GLY B 2 42  ? -1.988  24.821 12.206  1.00 31.21 ? 42  GLY H H    1 
ATOM   2160 H HA2  . GLY B 2 42  ? -2.743  22.904 12.665  1.00 30.96 ? 42  GLY H HA2  1 
ATOM   2161 H HA3  . GLY B 2 42  ? -4.131  23.339 12.049  1.00 30.96 ? 42  GLY H HA3  1 
ATOM   2162 N N    . LYS B 2 43  ? -2.191  22.782 9.715   1.00 21.55 ? 43  LYS H N    1 
ATOM   2163 C CA   . LYS B 2 43  ? -1.965  21.983 8.523   1.00 19.72 ? 43  LYS H CA   1 
ATOM   2164 C C    . LYS B 2 43  ? -0.488  21.580 8.430   1.00 16.68 ? 43  LYS H C    1 
ATOM   2165 O O    . LYS B 2 43  ? 0.324   21.895 9.306   1.00 17.23 ? 43  LYS H O    1 
ATOM   2166 C CB   . LYS B 2 43  ? -2.413  22.759 7.282   1.00 19.93 ? 43  LYS H CB   1 
ATOM   2167 C CG   . LYS B 2 43  ? -3.933  23.073 7.238   1.00 22.89 ? 43  LYS H CG   1 
ATOM   2168 H H    . LYS B 2 43  ? -1.789  23.543 9.701   1.00 25.92 ? 43  LYS H H    1 
ATOM   2169 H HA   . LYS B 2 43  ? -2.488  21.168 8.581   1.00 23.72 ? 43  LYS H HA   1 
ATOM   2170 H HB2  . LYS B 2 43  ? -1.938  23.605 7.258   1.00 23.98 ? 43  LYS H HB2  1 
ATOM   2171 H HB3  . LYS B 2 43  ? -2.198  22.235 6.494   1.00 23.98 ? 43  LYS H HB3  1 
ATOM   2172 N N    . GLY B 2 44  ? -0.148  20.873 7.351   1.00 18.71 ? 44  GLY H N    1 
ATOM   2173 C CA   . GLY B 2 44  ? 1.204   20.405 7.115   1.00 15.76 ? 44  GLY H CA   1 
ATOM   2174 C C    . GLY B 2 44  ? 2.020   21.398 6.320   1.00 19.01 ? 44  GLY H C    1 
ATOM   2175 O O    . GLY B 2 44  ? 1.692   22.581 6.208   1.00 18.54 ? 44  GLY H O    1 
ATOM   2176 H H    . GLY B 2 44  ? -0.700  20.650 6.731   1.00 22.52 ? 44  GLY H H    1 
ATOM   2177 H HA2  . GLY B 2 44  ? 1.646   20.256 7.965   1.00 18.97 ? 44  GLY H HA2  1 
ATOM   2178 H HA3  . GLY B 2 44  ? 1.174   19.570 6.623   1.00 18.97 ? 44  GLY H HA3  1 
ATOM   2179 N N    . LEU B 2 45  ? 3.140   20.908 5.807   1.00 11.90 ? 45  LEU H N    1 
ATOM   2180 C CA   . LEU B 2 45  ? 4.118   21.702 5.100   1.00 13.35 ? 45  LEU H CA   1 
ATOM   2181 C C    . LEU B 2 45  ? 3.775   21.752 3.627   1.00 14.02 ? 45  LEU H C    1 
ATOM   2182 O O    . LEU B 2 45  ? 3.500   20.716 3.004   1.00 15.20 ? 45  LEU H O    1 
ATOM   2183 C CB   . LEU B 2 45  ? 5.510   21.122 5.307   1.00 13.99 ? 45  LEU H CB   1 
ATOM   2184 C CG   . LEU B 2 45  ? 5.943   20.882 6.757   1.00 13.53 ? 45  LEU H CG   1 
ATOM   2185 C CD1  . LEU B 2 45  ? 7.209   20.058 6.873   1.00 15.28 ? 45  LEU H CD1  1 
ATOM   2186 C CD2  . LEU B 2 45  ? 6.067   22.193 7.445   1.00 16.73 ? 45  LEU H CD2  1 
ATOM   2187 H H    . LEU B 2 45  ? 3.362   20.079 5.862   1.00 14.34 ? 45  LEU H H    1 
ATOM   2188 H HA   . LEU B 2 45  ? 4.110   22.612 5.438   1.00 16.08 ? 45  LEU H HA   1 
ATOM   2189 H HB2  . LEU B 2 45  ? 5.549   20.266 4.852   1.00 16.85 ? 45  LEU H HB2  1 
ATOM   2190 H HB3  . LEU B 2 45  ? 6.152   21.735 4.916   1.00 16.85 ? 45  LEU H HB3  1 
ATOM   2191 H HG   . LEU B 2 45  ? 5.265   20.350 7.203   1.00 16.29 ? 45  LEU H HG   1 
ATOM   2192 H HD11 . LEU B 2 45  ? 7.399   19.901 7.811   1.00 18.40 ? 45  LEU H HD11 1 
ATOM   2193 H HD12 . LEU B 2 45  ? 7.078   19.212 6.416   1.00 18.40 ? 45  LEU H HD12 1 
ATOM   2194 H HD13 . LEU B 2 45  ? 7.941   20.545 6.463   1.00 18.40 ? 45  LEU H HD13 1 
ATOM   2195 H HD21 . LEU B 2 45  ? 6.432   22.051 8.332   1.00 20.14 ? 45  LEU H HD21 1 
ATOM   2196 H HD22 . LEU B 2 45  ? 6.659   22.764 6.931   1.00 20.14 ? 45  LEU H HD22 1 
ATOM   2197 H HD23 . LEU B 2 45  ? 5.189   22.600 7.510   1.00 20.14 ? 45  LEU H HD23 1 
ATOM   2198 N N    . GLU B 2 46  ? 3.822   22.943 3.061   1.00 11.12 ? 46  GLU H N    1 
ATOM   2199 C CA   . GLU B 2 46  ? 3.563   23.148 1.645   1.00 12.53 ? 46  GLU H CA   1 
ATOM   2200 C C    . GLU B 2 46  ? 4.709   23.939 1.010   1.00 12.59 ? 46  GLU H C    1 
ATOM   2201 O O    . GLU B 2 46  ? 4.935   25.114 1.340   1.00 11.53 ? 46  GLU H O    1 
ATOM   2202 C CB   . GLU B 2 46  ? 2.239   23.888 1.441   1.00 15.15 ? 46  GLU H CB   1 
ATOM   2203 C CG   . GLU B 2 46  ? 1.794   23.863 -0.035  1.00 17.35 ? 46  GLU H CG   1 
ATOM   2204 C CD   . GLU B 2 46  ? 0.738   24.910 -0.389  1.00 19.71 ? 46  GLU H CD   1 
ATOM   2205 O OE1  . GLU B 2 46  ? 0.278   25.657 0.499   1.00 18.61 ? 46  GLU H OE1  1 
ATOM   2206 O OE2  . GLU B 2 46  ? 0.329   24.905 -1.569  1.00 24.43 ? 46  GLU H OE2  1 
ATOM   2207 H H    . GLU B 2 46  ? 4.006   23.667 3.486   1.00 13.41 ? 46  GLU H H    1 
ATOM   2208 H HA   . GLU B 2 46  ? 3.529   22.281 1.212   1.00 15.10 ? 46  GLU H HA   1 
ATOM   2209 H HB2  . GLU B 2 46  ? 1.550   23.462 1.974   1.00 18.24 ? 46  GLU H HB2  1 
ATOM   2210 H HB3  . GLU B 2 46  ? 2.345   24.813 1.712   1.00 18.24 ? 46  GLU H HB3  1 
ATOM   2211 H HG2  . GLU B 2 46  ? 2.568   24.026 -0.596  1.00 20.88 ? 46  GLU H HG2  1 
ATOM   2212 H HG3  . GLU B 2 46  ? 1.419   22.990 -0.232  1.00 20.88 ? 46  GLU H HG3  1 
ATOM   2213 N N    . TRP B 2 47  ? 5.455   23.307 0.113   1.00 12.32 ? 47  TRP H N    1 
ATOM   2214 C CA   . TRP B 2 47  ? 6.448   24.027 -0.670  1.00 11.20 ? 47  TRP H CA   1 
ATOM   2215 C C    . TRP B 2 47  ? 5.761   25.087 -1.514  1.00 10.67 ? 47  TRP H C    1 
ATOM   2216 O O    . TRP B 2 47  ? 4.725   24.825 -2.131  1.00 14.01 ? 47  TRP H O    1 
ATOM   2217 C CB   . TRP B 2 47  ? 7.232   23.072 -1.567  1.00 9.15  ? 47  TRP H CB   1 
ATOM   2218 C CG   . TRP B 2 47  ? 8.205   23.753 -2.457  1.00 9.24  ? 47  TRP H CG   1 
ATOM   2219 C CD1  . TRP B 2 47  ? 9.425   24.312 -2.119  1.00 9.86  ? 47  TRP H CD1  1 
ATOM   2220 C CD2  . TRP B 2 47  ? 8.037   23.984 -3.853  1.00 11.34 ? 47  TRP H CD2  1 
ATOM   2221 N NE1  . TRP B 2 47  ? 10.007  24.846 -3.229  1.00 11.37 ? 47  TRP H NE1  1 
ATOM   2222 C CE2  . TRP B 2 47  ? 9.176   24.659 -4.301  1.00 12.58 ? 47  TRP H CE2  1 
ATOM   2223 C CE3  . TRP B 2 47  ? 7.042   23.662 -4.775  1.00 11.80 ? 47  TRP H CE3  1 
ATOM   2224 C CZ2  . TRP B 2 47  ? 9.324   25.030 -5.603  1.00 11.95 ? 47  TRP H CZ2  1 
ATOM   2225 C CZ3  . TRP B 2 47  ? 7.192   24.022 -6.034  1.00 11.07 ? 47  TRP H CZ3  1 
ATOM   2226 C CH2  . TRP B 2 47  ? 8.315   24.693 -6.458  1.00 13.28 ? 47  TRP H CH2  1 
ATOM   2227 H H    . TRP B 2 47  ? 5.407   22.466 -0.060  1.00 14.84 ? 47  TRP H H    1 
ATOM   2228 H HA   . TRP B 2 47  ? 7.080   24.453 -0.070  1.00 13.50 ? 47  TRP H HA   1 
ATOM   2229 H HB2  . TRP B 2 47  ? 7.726   22.453 -1.007  1.00 11.04 ? 47  TRP H HB2  1 
ATOM   2230 H HB3  . TRP B 2 47  ? 6.607   22.587 -2.128  1.00 11.04 ? 47  TRP H HB3  1 
ATOM   2231 H HD1  . TRP B 2 47  ? 9.792   24.321 -1.264  1.00 11.89 ? 47  TRP H HD1  1 
ATOM   2232 H HE1  . TRP B 2 47  ? 10.773  25.238 -3.252  1.00 13.70 ? 47  TRP H HE1  1 
ATOM   2233 H HE3  . TRP B 2 47  ? 6.282   23.199 -4.505  1.00 14.22 ? 47  TRP H HE3  1 
ATOM   2234 H HZ2  . TRP B 2 47  ? 10.076  25.491 -5.895  1.00 14.41 ? 47  TRP H HZ2  1 
ATOM   2235 H HZ3  . TRP B 2 47  ? 6.524   23.817 -6.648  1.00 13.35 ? 47  TRP H HZ3  1 
ATOM   2236 H HH2  . TRP B 2 47  ? 8.389   24.925 -7.355  1.00 16.00 ? 47  TRP H HH2  1 
ATOM   2237 N N    . VAL B 2 48  ? 6.334   26.277 -1.522  1.00 11.86 ? 48  VAL H N    1 
ATOM   2238 C CA   . VAL B 2 48  ? 5.796   27.423 -2.222  1.00 11.43 ? 48  VAL H CA   1 
ATOM   2239 C C    . VAL B 2 48  ? 6.624   27.745 -3.460  1.00 13.71 ? 48  VAL H C    1 
ATOM   2240 O O    . VAL B 2 48  ? 6.090   27.909 -4.554  1.00 13.26 ? 48  VAL H O    1 
ATOM   2241 C CB   . VAL B 2 48  ? 5.730   28.644 -1.272  1.00 13.52 ? 48  VAL H CB   1 
ATOM   2242 C CG1  . VAL B 2 48  ? 5.211   29.882 -2.011  1.00 19.02 ? 48  VAL H CG1  1 
ATOM   2243 C CG2  . VAL B 2 48  ? 4.895   28.343 -0.032  1.00 19.92 ? 48  VAL H CG2  1 
ATOM   2244 H H    . VAL B 2 48  ? 7.069   26.451 -1.110  1.00 14.30 ? 48  VAL H H    1 
ATOM   2245 H HA   . VAL B 2 48  ? 4.895   27.219 -2.518  1.00 13.78 ? 48  VAL H HA   1 
ATOM   2246 H HB   . VAL B 2 48  ? 6.630   28.839 -0.967  1.00 16.28 ? 48  VAL H HB   1 
ATOM   2247 H HG11 . VAL B 2 48  ? 5.151   30.621 -1.385  1.00 22.88 ? 48  VAL H HG11 1 
ATOM   2248 H HG12 . VAL B 2 48  ? 5.826   30.104 -2.727  1.00 22.88 ? 48  VAL H HG12 1 
ATOM   2249 H HG13 . VAL B 2 48  ? 4.334   29.687 -2.377  1.00 22.88 ? 48  VAL H HG13 1 
ATOM   2250 H HG21 . VAL B 2 48  ? 4.899   29.121 0.548   1.00 23.97 ? 48  VAL H HG21 1 
ATOM   2251 H HG22 . VAL B 2 48  ? 3.987   28.139 -0.304  1.00 23.97 ? 48  VAL H HG22 1 
ATOM   2252 H HG23 . VAL B 2 48  ? 5.280   27.584 0.432   1.00 23.97 ? 48  VAL H HG23 1 
ATOM   2253 N N    . THR B 2 49  ? 7.939   27.874 -3.297  1.00 11.80 ? 49  THR H N    1 
ATOM   2254 C CA   . THR B 2 49  ? 8.823   28.359 -4.349  1.00 12.88 ? 49  THR H CA   1 
ATOM   2255 C C    . THR B 2 49  ? 10.273  28.139 -3.982  1.00 12.04 ? 49  THR H C    1 
ATOM   2256 O O    . THR B 2 49  ? 10.660  28.175 -2.811  1.00 10.60 ? 49  THR H O    1 
ATOM   2257 C CB   . THR B 2 49  ? 8.557   29.842 -4.637  1.00 13.92 ? 49  THR H CB   1 
ATOM   2258 O OG1  . THR B 2 49  ? 9.446   30.305 -5.665  1.00 15.56 ? 49  THR H OG1  1 
ATOM   2259 C CG2  . THR B 2 49  ? 8.774   30.690 -3.392  1.00 13.64 ? 49  THR H CG2  1 
ATOM   2260 H H    . THR B 2 49  ? 8.352   27.681 -2.568  1.00 14.22 ? 49  THR H H    1 
ATOM   2261 H HA   . THR B 2 49  ? 8.664   27.839 -5.152  1.00 15.51 ? 49  THR H HA   1 
ATOM   2262 H HB   . THR B 2 49  ? 7.636   29.943 -4.924  1.00 16.76 ? 49  THR H HB   1 
ATOM   2263 H HG1  . THR B 2 49  ? 9.298   31.116 -5.830  1.00 18.73 ? 49  THR H HG1  1 
ATOM   2264 H HG21 . THR B 2 49  ? 8.613   31.625 -3.595  1.00 16.43 ? 49  THR H HG21 1 
ATOM   2265 H HG22 . THR B 2 49  ? 8.166   30.411 -2.690  1.00 16.43 ? 49  THR H HG22 1 
ATOM   2266 H HG23 . THR B 2 49  ? 9.686   30.589 -3.077  1.00 16.43 ? 49  THR H HG23 1 
ATOM   2267 N N    . GLY B 2 50  ? 11.074  27.932 -5.014  1.00 9.98  ? 50  GLY H N    1 
ATOM   2268 C CA   . GLY B 2 50  ? 12.503  27.747 -4.846  1.00 10.44 ? 50  GLY H CA   1 
ATOM   2269 C C    . GLY B 2 50  ? 13.250  28.469 -5.947  1.00 14.20 ? 50  GLY H C    1 
ATOM   2270 O O    . GLY B 2 50  ? 12.669  28.830 -6.981  1.00 12.07 ? 50  GLY H O    1 
ATOM   2271 H H    . GLY B 2 50  ? 10.810  27.894 -5.832  1.00 12.04 ? 50  GLY H H    1 
ATOM   2272 H HA2  . GLY B 2 50  ? 12.784  28.102 -3.988  1.00 12.59 ? 50  GLY H HA2  1 
ATOM   2273 H HA3  . GLY B 2 50  ? 12.721  26.802 -4.884  1.00 12.59 ? 50  GLY H HA3  1 
ATOM   2274 N N    . ILE B 2 51  ? 14.548  28.679 -5.729  1.00 12.08 ? 51  ILE H N    1 
ATOM   2275 C CA   . ILE B 2 51  ? 15.343  29.476 -6.641  1.00 12.25 ? 51  ILE H CA   1 
ATOM   2276 C C    . ILE B 2 51  ? 16.748  28.896 -6.736  1.00 13.79 ? 51  ILE H C    1 
ATOM   2277 O O    . ILE B 2 51  ? 17.351  28.512 -5.719  1.00 12.40 ? 51  ILE H O    1 
ATOM   2278 C CB   . ILE B 2 51  ? 15.453  30.927 -6.175  1.00 12.74 ? 51  ILE H CB   1 
ATOM   2279 C CG1  . ILE B 2 51  ? 16.208  31.779 -7.207  1.00 13.70 ? 51  ILE H CG1  1 
ATOM   2280 C CG2  . ILE B 2 51  ? 16.040  31.058 -4.860  1.00 13.17 ? 51  ILE H CG2  1 
ATOM   2281 C CD1  . ILE B 2 51  ? 15.772  33.278 -7.220  1.00 14.54 ? 51  ILE H CD1  1 
ATOM   2282 H H    . ILE B 2 51  ? 14.984  28.367 -5.056  1.00 14.55 ? 51  ILE H H    1 
ATOM   2283 H HA   . ILE B 2 51  ? 14.918  29.435 -7.512  1.00 14.76 ? 51  ILE H HA   1 
ATOM   2284 H HB   . ILE B 2 51  ? 14.545  31.259 -6.103  1.00 15.35 ? 51  ILE H HB   1 
ATOM   2285 H HG12 . ILE B 2 51  ? 17.156  31.747 -7.005  1.00 16.50 ? 51  ILE H HG12 1 
ATOM   2286 H HG13 . ILE B 2 51  ? 16.045  31.415 -8.092  1.00 16.50 ? 51  ILE H HG13 1 
ATOM   2287 H HG21 . ILE B 2 51  ? 15.953  31.979 -4.566  1.00 15.86 ? 51  ILE H HG21 1 
ATOM   2288 H HG22 . ILE B 2 51  ? 15.575  30.469 -4.246  1.00 15.86 ? 51  ILE H HG22 1 
ATOM   2289 H HG23 . ILE B 2 51  ? 16.978  30.814 -4.907  1.00 15.86 ? 51  ILE H HG23 1 
ATOM   2290 H HD11 . ILE B 2 51  ? 16.284  33.750 -7.896  1.00 17.51 ? 51  ILE H HD11 1 
ATOM   2291 H HD12 . ILE B 2 51  ? 14.826  33.330 -7.425  1.00 17.51 ? 51  ILE H HD12 1 
ATOM   2292 H HD13 . ILE B 2 51  ? 15.943  33.664 -6.347  1.00 17.51 ? 51  ILE H HD13 1 
ATOM   2293 N N    . SER B 2 52  ? 17.212  28.743 -7.978  1.00 10.01 ? 52  SER H N    1 
ATOM   2294 C CA   . SER B 2 52  ? 18.503  28.170 -8.291  1.00 11.59 ? 52  SER H CA   1 
ATOM   2295 C C    . SER B 2 52  ? 19.641  29.033 -7.737  1.00 13.69 ? 52  SER H C    1 
ATOM   2296 O O    . SER B 2 52  ? 19.485  30.215 -7.398  1.00 11.58 ? 52  SER H O    1 
ATOM   2297 C CB   . SER B 2 52  ? 18.606  27.922 -9.809  1.00 13.95 ? 52  SER H CB   1 
ATOM   2298 O OG   . SER B 2 52  ? 18.903  29.146 -10.470 1.00 16.57 ? 52  SER H OG   1 
ATOM   2299 H H    . SER B 2 52  ? 16.774  28.974 -8.681  1.00 12.07 ? 52  SER H H    1 
ATOM   2300 H HA   . SER B 2 52  ? 18.611  27.307 -7.862  1.00 13.96 ? 52  SER H HA   1 
ATOM   2301 H HB2  . SER B 2 52  ? 19.314  27.283 -9.983  1.00 16.81 ? 52  SER H HB2  1 
ATOM   2302 H HB3  . SER B 2 52  ? 17.760  27.577 -10.136 1.00 16.81 ? 52  SER H HB3  1 
ATOM   2303 H HG   . SER B 2 52  ? 19.026  29.008 -11.289 1.00 19.94 ? 52  SER H HG   1 
ATOM   2304 N N    . TYR B 2 53  ? 20.820  28.409 -7.733  1.00 12.62 ? 53  TYR H N    1 
ATOM   2305 C CA   . TYR B 2 53  ? 22.049  28.966 -7.175  1.00 14.66 ? 53  TYR H CA   1 
ATOM   2306 C C    . TYR B 2 53  ? 22.293  30.430 -7.504  1.00 16.30 ? 53  TYR H C    1 
ATOM   2307 O O    . TYR B 2 53  ? 22.475  31.252 -6.597  1.00 16.52 ? 53  TYR H O    1 
ATOM   2308 C CB   . TYR B 2 53  ? 23.212  28.098 -7.657  1.00 15.71 ? 53  TYR H CB   1 
ATOM   2309 C CG   . TYR B 2 53  ? 23.008  26.628 -7.425  1.00 14.67 ? 53  TYR H CG   1 
ATOM   2310 C CD1  . TYR B 2 53  ? 23.301  26.087 -6.182  1.00 14.58 ? 53  TYR H CD1  1 
ATOM   2311 C CD2  . TYR B 2 53  ? 22.457  25.793 -8.413  1.00 15.63 ? 53  TYR H CD2  1 
ATOM   2312 C CE1  . TYR B 2 53  ? 23.112  24.763 -5.938  1.00 12.66 ? 53  TYR H CE1  1 
ATOM   2313 C CE2  . TYR B 2 53  ? 22.227  24.497 -8.173  1.00 13.64 ? 53  TYR H CE2  1 
ATOM   2314 C CZ   . TYR B 2 53  ? 22.572  23.951 -6.924  1.00 13.33 ? 53  TYR H CZ   1 
ATOM   2315 O OH   . TYR B 2 53  ? 22.368  22.610 -6.610  1.00 12.06 ? 53  TYR H OH   1 
ATOM   2316 H H    . TYR B 2 53  ? 20.940  27.625 -8.065  1.00 15.21 ? 53  TYR H H    1 
ATOM   2317 H HA   . TYR B 2 53  ? 21.978  28.939 -6.208  1.00 17.66 ? 53  TYR H HA   1 
ATOM   2318 H HB2  . TYR B 2 53  ? 23.327  28.233 -8.611  1.00 18.91 ? 53  TYR H HB2  1 
ATOM   2319 H HB3  . TYR B 2 53  ? 24.016  28.363 -7.185  1.00 18.91 ? 53  TYR H HB3  1 
ATOM   2320 H HD1  . TYR B 2 53  ? 23.631  26.636 -5.508  1.00 17.55 ? 53  TYR H HD1  1 
ATOM   2321 H HD2  . TYR B 2 53  ? 22.249  26.148 -9.248  1.00 18.82 ? 53  TYR H HD2  1 
ATOM   2322 H HE1  . TYR B 2 53  ? 23.344  24.403 -5.113  1.00 15.25 ? 53  TYR H HE1  1 
ATOM   2323 H HE2  . TYR B 2 53  ? 21.841  23.961 -8.828  1.00 16.43 ? 53  TYR H HE2  1 
ATOM   2324 H HH   . TYR B 2 53  ? 22.142  22.185 -7.298  1.00 14.53 ? 53  TYR H HH   1 
ATOM   2325 N N    . ASP B 2 54  ? 22.355  30.754 -8.787  1.00 14.07 ? 54  ASP H N    1 
ATOM   2326 C CA   . ASP B 2 54  ? 22.692  32.109 -9.205  1.00 19.85 ? 54  ASP H CA   1 
ATOM   2327 C C    . ASP B 2 54  ? 21.459  32.966 -9.450  1.00 18.98 ? 54  ASP H C    1 
ATOM   2328 O O    . ASP B 2 54  ? 21.588  34.068 -9.995  1.00 16.31 ? 54  ASP H O    1 
ATOM   2329 C CB   . ASP B 2 54  ? 23.588  32.102 -10.460 1.00 20.75 ? 54  ASP H CB   1 
ATOM   2330 C CG   . ASP B 2 54  ? 22.946  31.456 -11.666 1.00 28.32 ? 54  ASP H CG   1 
ATOM   2331 O OD1  . ASP B 2 54  ? 21.711  31.268 -11.706 1.00 22.93 ? 54  ASP H OD1  1 
ATOM   2332 O OD2  . ASP B 2 54  ? 23.684  31.191 -12.633 1.00 33.59 ? 54  ASP H OD2  1 
ATOM   2333 H H    . ASP B 2 54  ? 22.206  30.208 -9.434  1.00 16.94 ? 54  ASP H H    1 
ATOM   2334 H HA   . ASP B 2 54  ? 23.208  32.518 -8.493  1.00 23.88 ? 54  ASP H HA   1 
ATOM   2335 H HB2  . ASP B 2 54  ? 23.803  33.018 -10.695 1.00 24.96 ? 54  ASP H HB2  1 
ATOM   2336 H HB3  . ASP B 2 54  ? 24.401  31.611 -10.260 1.00 24.96 ? 54  ASP H HB3  1 
ATOM   2337 N N    . GLY B 2 55  ? 20.261  32.474 -9.093  1.00 14.60 ? 55  GLY H N    1 
ATOM   2338 C CA   . GLY B 2 55  ? 19.054  33.246 -9.211  1.00 19.92 ? 55  GLY H CA   1 
ATOM   2339 C C    . GLY B 2 55  ? 18.363  33.142 -10.552 1.00 17.24 ? 55  GLY H C    1 
ATOM   2340 O O    . GLY B 2 55  ? 17.263  33.689 -10.694 1.00 20.94 ? 55  GLY H O    1 
ATOM   2341 H H    . GLY B 2 55  ? 20.138  31.683 -8.778  1.00 17.58 ? 55  GLY H H    1 
ATOM   2342 H HA2  . GLY B 2 55  ? 18.427  32.950 -8.532  1.00 23.96 ? 55  GLY H HA2  1 
ATOM   2343 H HA3  . GLY B 2 55  ? 19.266  34.180 -9.059  1.00 23.96 ? 55  GLY H HA3  1 
ATOM   2344 N N    . ARG B 2 56  ? 18.970  32.476 -11.536 1.00 15.33 ? 56  ARG H N    1 
ATOM   2345 C CA   . ARG B 2 56  ? 18.421  32.497 -12.885 1.00 19.52 ? 56  ARG H CA   1 
ATOM   2346 C C    . ARG B 2 56  ? 17.128  31.704 -13.002 1.00 19.18 ? 56  ARG H C    1 
ATOM   2347 O O    . ARG B 2 56  ? 16.252  32.086 -13.788 1.00 23.33 ? 56  ARG H O    1 
ATOM   2348 C CB   . ARG B 2 56  ? 19.448  31.973 -13.874 1.00 23.65 ? 56  ARG H CB   1 
ATOM   2349 C CG   . ARG B 2 56  ? 20.453  33.038 -14.307 1.00 24.38 ? 56  ARG H CG   1 
ATOM   2350 C CD   . ARG B 2 56  ? 21.482  32.517 -15.331 1.00 22.66 ? 56  ARG H CD   1 
ATOM   2351 N NE   . ARG B 2 56  ? 21.904  31.170 -14.994 1.00 25.68 ? 56  ARG H NE   1 
ATOM   2352 C CZ   . ARG B 2 56  ? 21.717  30.099 -15.750 1.00 26.72 ? 56  ARG H CZ   1 
ATOM   2353 N NH1  . ARG B 2 56  ? 21.047  30.162 -16.886 1.00 32.91 ? 56  ARG H NH1  1 
ATOM   2354 N NH2  . ARG B 2 56  ? 22.194  28.930 -15.341 1.00 34.65 ? 56  ARG H NH2  1 
ATOM   2355 H H    . ARG B 2 56  ? 19.689  32.013 -11.448 1.00 18.46 ? 56  ARG H H    1 
ATOM   2356 H HA   . ARG B 2 56  ? 18.216  33.419 -13.105 1.00 23.48 ? 56  ARG H HA   1 
ATOM   2357 H HB2  . ARG B 2 56  ? 19.940  31.246 -13.462 1.00 28.44 ? 56  ARG H HB2  1 
ATOM   2358 H HB3  . ARG B 2 56  ? 18.988  31.655 -14.667 1.00 28.44 ? 56  ARG H HB3  1 
ATOM   2359 H HG2  . ARG B 2 56  ? 19.974  33.777 -14.715 1.00 29.32 ? 56  ARG H HG2  1 
ATOM   2360 H HG3  . ARG B 2 56  ? 20.939  33.349 -13.527 1.00 29.32 ? 56  ARG H HG3  1 
ATOM   2361 H HD2  . ARG B 2 56  ? 21.083  32.504 -16.215 1.00 27.25 ? 56  ARG H HD2  1 
ATOM   2362 H HD3  . ARG B 2 56  ? 22.262  33.094 -15.328 1.00 27.25 ? 56  ARG H HD3  1 
ATOM   2363 H HE   . ARG B 2 56  ? 22.307  31.057 -14.243 1.00 30.88 ? 56  ARG H HE   1 
ATOM   2364 H HH11 . ARG B 2 56  ? 20.719  30.912 -17.151 1.00 39.56 ? 56  ARG H HH11 1 
ATOM   2365 H HH12 . ARG B 2 56  ? 20.938  29.454 -17.361 1.00 39.56 ? 56  ARG H HH12 1 
ATOM   2366 H HH21 . ARG B 2 56  ? 22.617  28.876 -14.595 1.00 41.64 ? 56  ARG H HH21 1 
ATOM   2367 H HH22 . ARG B 2 56  ? 22.080  28.227 -15.823 1.00 41.64 ? 56  ARG H HH22 1 
ATOM   2368 N N    . HIS B 2 57  ? 16.977  30.607 -12.253 1.00 14.04 ? 57  HIS H N    1 
ATOM   2369 C CA   . HIS B 2 57  ? 15.818  29.717 -12.403 1.00 15.41 ? 57  HIS H CA   1 
ATOM   2370 C C    . HIS B 2 57  ? 14.954  29.789 -11.142 1.00 15.43 ? 57  HIS H C    1 
ATOM   2371 O O    . HIS B 2 57  ? 15.446  29.588 -10.026 1.00 13.89 ? 57  HIS H O    1 
ATOM   2372 C CB   . HIS B 2 57  ? 16.273  28.277 -12.671 1.00 14.81 ? 57  HIS H CB   1 
ATOM   2373 C CG   . HIS B 2 57  ? 17.214  28.162 -13.824 1.00 17.40 ? 57  HIS H CG   1 
ATOM   2374 N ND1  . HIS B 2 57  ? 16.860  28.585 -15.084 1.00 20.78 ? 57  HIS H ND1  1 
ATOM   2375 C CD2  . HIS B 2 57  ? 18.487  27.712 -13.916 1.00 19.00 ? 57  HIS H CD2  1 
ATOM   2376 C CE1  . HIS B 2 57  ? 17.867  28.380 -15.913 1.00 20.02 ? 57  HIS H CE1  1 
ATOM   2377 N NE2  . HIS B 2 57  ? 18.859  27.830 -15.234 1.00 21.21 ? 57  HIS H NE2  1 
ATOM   2378 H H    . HIS B 2 57  ? 17.535  30.355 -11.649 1.00 16.91 ? 57  HIS H H    1 
ATOM   2379 H HA   . HIS B 2 57  ? 15.275  30.007 -13.153 1.00 18.55 ? 57  HIS H HA   1 
ATOM   2380 H HB2  . HIS B 2 57  ? 16.724  27.938 -11.882 1.00 17.84 ? 57  HIS H HB2  1 
ATOM   2381 H HB3  . HIS B 2 57  ? 15.494  27.733 -12.866 1.00 17.84 ? 57  HIS H HB3  1 
ATOM   2382 H HD1  . HIS B 2 57  ? 16.102  28.930 -15.298 1.00 25.00 ? 57  HIS H HD1  1 
ATOM   2383 H HD2  . HIS B 2 57  ? 19.011  27.385 -13.220 1.00 22.86 ? 57  HIS H HD2  1 
ATOM   2384 H HE1  . HIS B 2 57  ? 17.876  28.586 -16.820 1.00 24.08 ? 57  HIS H HE1  1 
ATOM   2385 N N    . LYS B 2 58  ? 13.669  30.040 -11.334 1.00 15.49 ? 58  LYS H N    1 
ATOM   2386 C CA   . LYS B 2 58  ? 12.693  30.154 -10.256 1.00 15.71 ? 58  LYS H CA   1 
ATOM   2387 C C    . LYS B 2 58  ? 11.633  29.114 -10.516 1.00 14.93 ? 58  LYS H C    1 
ATOM   2388 O O    . LYS B 2 58  ? 11.187  28.970 -11.656 1.00 15.57 ? 58  LYS H O    1 
ATOM   2389 C CB   . LYS B 2 58  ? 12.097  31.552 -10.171 1.00 16.67 ? 58  LYS H CB   1 
ATOM   2390 C CG   . LYS B 2 58  ? 13.191  32.617 -10.098 1.00 20.14 ? 58  LYS H CG   1 
ATOM   2391 C CD   . LYS B 2 58  ? 12.976  33.804 -10.992 1.00 29.52 ? 58  LYS H CD   1 
ATOM   2392 C CE   . LYS B 2 58  ? 14.109  34.821 -10.856 1.00 32.91 ? 58  LYS H CE   1 
ATOM   2393 N NZ   . LYS B 2 58  ? 15.090  34.795 -12.002 1.00 28.17 ? 58  LYS H NZ   1 
ATOM   2394 H H    . LYS B 2 58  ? 13.321  30.153 -12.113 1.00 18.65 ? 58  LYS H H    1 
ATOM   2395 H HA   . LYS B 2 58  ? 13.107  29.988 -9.395  1.00 18.91 ? 58  LYS H HA   1 
ATOM   2396 H HB2  . LYS B 2 58  ? 11.557  31.720 -10.960 1.00 20.06 ? 58  LYS H HB2  1 
ATOM   2397 H HB3  . LYS B 2 58  ? 11.548  31.620 -9.374  1.00 20.06 ? 58  LYS H HB3  1 
ATOM   2398 H HG2  . LYS B 2 58  ? 13.242  32.945 -9.187  1.00 24.23 ? 58  LYS H HG2  1 
ATOM   2399 H HG3  . LYS B 2 58  ? 14.034  32.210 -10.353 1.00 24.23 ? 58  LYS H HG3  1 
ATOM   2400 H HD2  . LYS B 2 58  ? 12.941  33.508 -11.915 1.00 35.49 ? 58  LYS H HD2  1 
ATOM   2401 H HD3  . LYS B 2 58  ? 12.144  34.240 -10.752 1.00 35.49 ? 58  LYS H HD3  1 
ATOM   2402 H HE2  . LYS B 2 58  ? 13.727  35.711 -10.814 1.00 39.55 ? 58  LYS H HE2  1 
ATOM   2403 H HE3  . LYS B 2 58  ? 14.602  34.633 -10.041 1.00 39.55 ? 58  LYS H HE3  1 
ATOM   2404 H HZ1  . LYS B 2 58  ? 15.716  35.415 -11.881 1.00 33.87 ? 58  LYS H HZ1  1 
ATOM   2405 H HZ2  . LYS B 2 58  ? 15.480  33.996 -12.051 1.00 33.87 ? 58  LYS H HZ2  1 
ATOM   2406 H HZ3  . LYS B 2 58  ? 14.667  34.957 -12.768 1.00 33.87 ? 58  LYS H HZ3  1 
ATOM   2407 N N    . TYR B 2 59  ? 11.282  28.373 -9.460  1.00 13.20 ? 59  TYR H N    1 
ATOM   2408 C CA   . TYR B 2 59  ? 10.311  27.281 -9.481  1.00 13.27 ? 59  TYR H CA   1 
ATOM   2409 C C    . TYR B 2 59  ? 9.156   27.606 -8.545  1.00 10.79 ? 59  TYR H C    1 
ATOM   2410 O O    . TYR B 2 59  ? 9.379   28.141 -7.461  1.00 11.93 ? 59  TYR H O    1 
ATOM   2411 C CB   . TYR B 2 59  ? 10.960  25.991 -9.045  1.00 13.42 ? 59  TYR H CB   1 
ATOM   2412 C CG   . TYR B 2 59  ? 12.305  25.759 -9.737  1.00 12.03 ? 59  TYR H CG   1 
ATOM   2413 C CD1  . TYR B 2 59  ? 12.354  25.286 -11.045 1.00 13.61 ? 59  TYR H CD1  1 
ATOM   2414 C CD2  . TYR B 2 59  ? 13.513  26.004 -9.093  1.00 14.40 ? 59  TYR H CD2  1 
ATOM   2415 C CE1  . TYR B 2 59  ? 13.580  25.028 -11.697 1.00 12.27 ? 59  TYR H CE1  1 
ATOM   2416 C CE2  . TYR B 2 59  ? 14.703  25.799 -9.711  1.00 15.32 ? 59  TYR H CE2  1 
ATOM   2417 C CZ   . TYR B 2 59  ? 14.756  25.303 -11.025 1.00 12.70 ? 59  TYR H CZ   1 
ATOM   2418 O OH   . TYR B 2 59  ? 15.986  25.084 -11.557 1.00 14.25 ? 59  TYR H OH   1 
ATOM   2419 H H    . TYR B 2 59  ? 11.615  28.493 -8.676  1.00 15.90 ? 59  TYR H H    1 
ATOM   2420 H HA   . TYR B 2 59  ? 9.958   27.171 -10.377 1.00 15.98 ? 59  TYR H HA   1 
ATOM   2421 H HB2  . TYR B 2 59  ? 11.113  26.020 -8.088  1.00 16.17 ? 59  TYR H HB2  1 
ATOM   2422 H HB3  . TYR B 2 59  ? 10.375  25.250 -9.265  1.00 16.17 ? 59  TYR H HB3  1 
ATOM   2423 H HD1  . TYR B 2 59  ? 11.559  25.135 -11.502 1.00 16.39 ? 59  TYR H HD1  1 
ATOM   2424 H HD2  . TYR B 2 59  ? 13.505  26.315 -8.217  1.00 17.34 ? 59  TYR H HD2  1 
ATOM   2425 H HE1  . TYR B 2 59  ? 13.596  24.681 -12.560 1.00 14.79 ? 59  TYR H HE1  1 
ATOM   2426 H HE2  . TYR B 2 59  ? 15.494  25.990 -9.260  1.00 18.45 ? 59  TYR H HE2  1 
ATOM   2427 H HH   . TYR B 2 59  ? 15.912  24.788 -12.339 1.00 17.16 ? 59  TYR H HH   1 
ATOM   2428 N N    . TYR B 2 60  ? 7.912   27.364 -8.997  1.00 11.79 ? 60  TYR H N    1 
ATOM   2429 C CA   . TYR B 2 60  ? 6.736   27.755 -8.226  1.00 13.40 ? 60  TYR H CA   1 
ATOM   2430 C C    . TYR B 2 60  ? 5.730   26.620 -8.109  1.00 12.52 ? 60  TYR H C    1 
ATOM   2431 O O    . TYR B 2 60  ? 5.494   25.876 -9.051  1.00 15.37 ? 60  TYR H O    1 
ATOM   2432 C CB   . TYR B 2 60  ? 6.011   28.958 -8.843  1.00 13.57 ? 60  TYR H CB   1 
ATOM   2433 C CG   . TYR B 2 60  ? 6.849   30.173 -8.939  1.00 14.81 ? 60  TYR H CG   1 
ATOM   2434 C CD1  . TYR B 2 60  ? 6.972   31.001 -7.848  1.00 13.98 ? 60  TYR H CD1  1 
ATOM   2435 C CD2  . TYR B 2 60  ? 7.569   30.482 -10.087 1.00 15.06 ? 60  TYR H CD2  1 
ATOM   2436 C CE1  . TYR B 2 60  ? 7.781   32.135 -7.869  1.00 15.96 ? 60  TYR H CE1  1 
ATOM   2437 C CE2  . TYR B 2 60  ? 8.376   31.657 -10.136 1.00 15.59 ? 60  TYR H CE2  1 
ATOM   2438 C CZ   . TYR B 2 60  ? 8.455   32.461 -9.004  1.00 15.96 ? 60  TYR H CZ   1 
ATOM   2439 O OH   . TYR B 2 60  ? 9.218   33.582 -8.915  1.00 14.33 ? 60  TYR H OH   1 
ATOM   2440 H H    . TYR B 2 60  ? 7.734   26.976 -9.744  1.00 14.20 ? 60  TYR H H    1 
ATOM   2441 H HA   . TYR B 2 60  ? 7.052   27.979 -7.336  1.00 16.15 ? 60  TYR H HA   1 
ATOM   2442 H HB2  . TYR B 2 60  ? 5.725   28.724 -9.740  1.00 16.34 ? 60  TYR H HB2  1 
ATOM   2443 H HB3  . TYR B 2 60  ? 5.240   29.173 -8.295  1.00 16.34 ? 60  TYR H HB3  1 
ATOM   2444 H HD1  . TYR B 2 60  ? 6.501   30.798 -7.072  1.00 16.84 ? 60  TYR H HD1  1 
ATOM   2445 H HD2  . TYR B 2 60  ? 7.524   29.920 -10.827 1.00 18.13 ? 60  TYR H HD2  1 
ATOM   2446 H HE1  . TYR B 2 60  ? 7.860   32.667 -7.110  1.00 19.21 ? 60  TYR H HE1  1 
ATOM   2447 H HE2  . TYR B 2 60  ? 8.840   31.881 -10.910 1.00 18.77 ? 60  TYR H HE2  1 
ATOM   2448 H HH   . TYR B 2 60  ? 9.610   33.722 -9.644  1.00 17.25 ? 60  TYR H HH   1 
ATOM   2449 N N    . ALA B 2 61  ? 5.154   26.487 -6.928  1.00 13.01 ? 61  ALA H N    1 
ATOM   2450 C CA   . ALA B 2 61  ? 3.915   25.746 -6.784  1.00 12.33 ? 61  ALA H CA   1 
ATOM   2451 C C    . ALA B 2 61  ? 2.787   26.368 -7.621  1.00 17.45 ? 61  ALA H C    1 
ATOM   2452 O O    . ALA B 2 61  ? 2.692   27.588 -7.775  1.00 17.17 ? 61  ALA H O    1 
ATOM   2453 C CB   . ALA B 2 61  ? 3.528   25.696 -5.298  1.00 14.95 ? 61  ALA H CB   1 
ATOM   2454 H H    . ALA B 2 61  ? 5.459   26.815 -6.194  1.00 15.67 ? 61  ALA H H    1 
ATOM   2455 H HA   . ALA B 2 61  ? 4.035   24.839 -7.107  1.00 14.85 ? 61  ALA H HA   1 
ATOM   2456 H HB1  . ALA B 2 61  ? 2.740   25.140 -5.196  1.00 18.01 ? 61  ALA H HB1  1 
ATOM   2457 H HB2  . ALA B 2 61  ? 4.265   25.321 -4.792  1.00 18.01 ? 61  ALA H HB2  1 
ATOM   2458 H HB3  . ALA B 2 61  ? 3.339   26.596 -4.991  1.00 18.01 ? 61  ALA H HB3  1 
ATOM   2459 N N    . ASP B 2 62  ? 1.950   25.508 -8.198  1.00 17.08 ? 62  ASP H N    1 
ATOM   2460 C CA   . ASP B 2 62  ? 0.838   25.993 -9.014  1.00 20.28 ? 62  ASP H CA   1 
ATOM   2461 C C    . ASP B 2 62  ? 0.015   27.000 -8.221  1.00 21.22 ? 62  ASP H C    1 
ATOM   2462 O O    . ASP B 2 62  ? -0.453  28.001 -8.762  1.00 32.42 ? 62  ASP H O    1 
ATOM   2463 C CB   . ASP B 2 62  ? -0.027  24.806 -9.436  1.00 21.78 ? 62  ASP H CB   1 
ATOM   2464 C CG   . ASP B 2 62  ? 0.588   23.988 -10.583 1.00 27.14 ? 62  ASP H CG   1 
ATOM   2465 O OD1  . ASP B 2 62  ? 1.648   24.319 -11.161 1.00 30.00 ? 62  ASP H OD1  1 
ATOM   2466 O OD2  . ASP B 2 62  ? 0.067   22.897 -10.835 1.00 28.75 ? 62  ASP H OD2  1 
ATOM   2467 H H    . ASP B 2 62  ? 2.001   24.652 -8.135  1.00 20.55 ? 62  ASP H H    1 
ATOM   2468 H HA   . ASP B 2 62  ? 1.170   26.425 -9.816  1.00 24.40 ? 62  ASP H HA   1 
ATOM   2469 H HB2  . ASP B 2 62  ? -0.142  24.215 -8.676  1.00 26.20 ? 62  ASP H HB2  1 
ATOM   2470 H HB3  . ASP B 2 62  ? -0.889  25.136 -9.733  1.00 26.20 ? 62  ASP H HB3  1 
ATOM   2471 N N    . SER B 2 63  ? -0.124  26.779 -6.915  1.00 25.37 ? 63  SER H N    1 
ATOM   2472 C CA   . SER B 2 63  ? -1.017  27.624 -6.123  1.00 29.62 ? 63  SER H CA   1 
ATOM   2473 C C    . SER B 2 63  ? -0.595  29.088 -6.125  1.00 31.41 ? 63  SER H C    1 
ATOM   2474 O O    . SER B 2 63  ? -1.445  29.968 -5.917  1.00 29.92 ? 63  SER H O    1 
ATOM   2475 C CB   . SER B 2 63  ? -1.099  27.131 -4.682  1.00 19.42 ? 63  SER H CB   1 
ATOM   2476 O OG   . SER B 2 63  ? 0.168   26.718 -4.137  1.00 33.77 ? 63  SER H OG   1 
ATOM   2477 H H    . SER B 2 63  ? 0.277   26.161 -6.472  1.00 30.50 ? 63  SER H H    1 
ATOM   2478 H HA   . SER B 2 63  ? -1.898  27.558 -6.524  1.00 35.60 ? 63  SER H HA   1 
ATOM   2479 H HB2  . SER B 2 63  ? -1.446  27.852 -4.134  1.00 23.36 ? 63  SER H HB2  1 
ATOM   2480 H HB3  . SER B 2 63  ? -1.704  26.373 -4.654  1.00 23.36 ? 63  SER H HB3  1 
ATOM   2481 H HG   . SER B 2 63  ? 0.070   26.464 -3.343  1.00 40.58 ? 63  SER H HG   1 
ATOM   2482 N N    . VAL B 2 64  ? 0.683   29.379 -6.376  1.00 22.26 ? 64  VAL H N    1 
ATOM   2483 C CA   . VAL B 2 64  ? 1.211   30.728 -6.201  1.00 20.96 ? 64  VAL H CA   1 
ATOM   2484 C C    . VAL B 2 64  ? 1.801   31.293 -7.471  1.00 21.24 ? 64  VAL H C    1 
ATOM   2485 O O    . VAL B 2 64  ? 2.132   32.492 -7.500  1.00 21.97 ? 64  VAL H O    1 
ATOM   2486 C CB   . VAL B 2 64  ? 2.271   30.792 -5.086  1.00 19.00 ? 64  VAL H CB   1 
ATOM   2487 C CG1  . VAL B 2 64  ? 1.670   30.392 -3.769  1.00 19.86 ? 64  VAL H CG1  1 
ATOM   2488 C CG2  . VAL B 2 64  ? 3.494   29.983 -5.437  1.00 19.73 ? 64  VAL H CG2  1 
ATOM   2489 H H    . VAL B 2 64  ? 1.265   28.808 -6.649  1.00 26.77 ? 64  VAL H H    1 
ATOM   2490 H HA   . VAL B 2 64  ? 0.471   31.297 -5.936  1.00 25.22 ? 64  VAL H HA   1 
ATOM   2491 H HB   . VAL B 2 64  ? 2.577   31.708 -4.994  1.00 22.87 ? 64  VAL H HB   1 
ATOM   2492 H HG11 . VAL B 2 64  ? 2.367   30.379 -3.094  1.00 23.89 ? 64  VAL H HG11 1 
ATOM   2493 H HG12 . VAL B 2 64  ? 0.986   31.035 -3.525  1.00 23.89 ? 64  VAL H HG12 1 
ATOM   2494 H HG13 . VAL B 2 64  ? 1.278   29.509 -3.855  1.00 23.89 ? 64  VAL H HG13 1 
ATOM   2495 H HG21 . VAL B 2 64  ? 4.118   30.016 -4.695  1.00 23.73 ? 64  VAL H HG21 1 
ATOM   2496 H HG22 . VAL B 2 64  ? 3.229   29.065 -5.605  1.00 23.73 ? 64  VAL H HG22 1 
ATOM   2497 H HG23 . VAL B 2 64  ? 3.905   30.359 -6.231  1.00 23.73 ? 64  VAL H HG23 1 
ATOM   2498 N N    . LYS B 2 65  ? 1.958   30.476 -8.515  1.00 21.16 ? 65  LYS H N    1 
ATOM   2499 C CA   . LYS B 2 65  ? 2.518   30.950 -9.765  1.00 25.53 ? 65  LYS H CA   1 
ATOM   2500 C C    . LYS B 2 65  ? 1.621   32.056 -10.295 1.00 26.73 ? 65  LYS H C    1 
ATOM   2501 O O    . LYS B 2 65  ? 0.391   31.940 -10.270 1.00 28.24 ? 65  LYS H O    1 
ATOM   2502 C CB   . LYS B 2 65  ? 2.644   29.785 -10.757 1.00 24.73 ? 65  LYS H CB   1 
ATOM   2503 H H    . LYS B 2 65  ? 1.746   29.642 -8.518  1.00 25.45 ? 65  LYS H H    1 
ATOM   2504 H HA   . LYS B 2 65  ? 3.413   31.305 -9.644  1.00 30.69 ? 65  LYS H HA   1 
ATOM   2505 N N    . GLY B 2 66  ? 2.228   33.160 -10.689 1.00 26.22 ? 66  GLY H N    1 
ATOM   2506 C CA   . GLY B 2 66  ? 1.492   34.305 -11.151 1.00 28.47 ? 66  GLY H CA   1 
ATOM   2507 C C    . GLY B 2 66  ? 1.226   35.338 -10.074 1.00 28.44 ? 66  GLY H C    1 
ATOM   2508 O O    . GLY B 2 66  ? 0.993   36.504 -10.392 1.00 28.13 ? 66  GLY H O    1 
ATOM   2509 H H    . GLY B 2 66  ? 3.081   33.266 -10.696 1.00 31.53 ? 66  GLY H H    1 
ATOM   2510 H HA2  . GLY B 2 66  ? 1.992   34.735 -11.862 1.00 34.22 ? 66  GLY H HA2  1 
ATOM   2511 H HA3  . GLY B 2 66  ? 0.637   34.010 -11.501 1.00 34.22 ? 66  GLY H HA3  1 
ATOM   2512 N N    . ARG B 2 67  ? 1.252   34.946 -8.804  1.00 20.87 ? 67  ARG H N    1 
ATOM   2513 C CA   . ARG B 2 67  ? 1.020   35.909 -7.726  1.00 18.22 ? 67  ARG H CA   1 
ATOM   2514 C C    . ARG B 2 67  ? 2.239   36.162 -6.858  1.00 18.55 ? 67  ARG H C    1 
ATOM   2515 O O    . ARG B 2 67  ? 2.450   37.289 -6.416  1.00 20.33 ? 67  ARG H O    1 
ATOM   2516 C CB   . ARG B 2 67  ? -0.135  35.450 -6.834  1.00 21.40 ? 67  ARG H CB   1 
ATOM   2517 C CG   . ARG B 2 67  ? -1.361  34.827 -7.544  1.00 23.17 ? 67  ARG H CG   1 
ATOM   2518 C CD   . ARG B 2 67  ? -2.424  34.629 -6.508  1.00 21.37 ? 67  ARG H CD   1 
ATOM   2519 N NE   . ARG B 2 67  ? -2.153  33.415 -5.746  1.00 17.49 ? 67  ARG H NE   1 
ATOM   2520 C CZ   . ARG B 2 67  ? -2.190  33.337 -4.422  1.00 23.30 ? 67  ARG H CZ   1 
ATOM   2521 N NH1  . ARG B 2 67  ? -2.563  34.372 -3.674  1.00 22.99 ? 67  ARG H NH1  1 
ATOM   2522 N NH2  . ARG B 2 67  ? -1.837  32.201 -3.831  1.00 21.03 ? 67  ARG H NH2  1 
ATOM   2523 H H    . ARG B 2 67  ? 1.399   34.140 -8.543  1.00 25.10 ? 67  ARG H H    1 
ATOM   2524 H HA   . ARG B 2 67  ? 0.766   36.753 -8.130  1.00 21.93 ? 67  ARG H HA   1 
ATOM   2525 H HB2  . ARG B 2 67  ? 0.207   34.780 -6.221  1.00 25.74 ? 67  ARG H HB2  1 
ATOM   2526 H HB3  . ARG B 2 67  ? -0.456  36.220 -6.339  1.00 25.74 ? 67  ARG H HB3  1 
ATOM   2527 H HG2  . ARG B 2 67  ? -1.691  35.424 -8.233  1.00 27.87 ? 67  ARG H HG2  1 
ATOM   2528 H HG3  . ARG B 2 67  ? -1.126  33.969 -7.932  1.00 27.87 ? 67  ARG H HG3  1 
ATOM   2529 H HD2  . ARG B 2 67  ? -2.432  35.384 -5.900  1.00 25.71 ? 67  ARG H HD2  1 
ATOM   2530 H HD3  . ARG B 2 67  ? -3.288  34.540 -6.939  1.00 25.71 ? 67  ARG H HD3  1 
ATOM   2531 H HE   . ARG B 2 67  ? -1.955  32.702 -6.184  1.00 21.05 ? 67  ARG H HE   1 
ATOM   2532 H HH11 . ARG B 2 67  ? -2.788  35.113 -4.047  1.00 27.65 ? 67  ARG H HH11 1 
ATOM   2533 H HH12 . ARG B 2 67  ? -2.580  34.298 -2.817  1.00 27.65 ? 67  ARG H HH12 1 
ATOM   2534 H HH21 . ARG B 2 67  ? -1.588  31.528 -4.306  1.00 25.29 ? 67  ARG H HH21 1 
ATOM   2535 H HH22 . ARG B 2 67  ? -1.857  32.138 -2.973  1.00 25.29 ? 67  ARG H HH22 1 
ATOM   2536 N N    . PHE B 2 68  ? 3.055   35.152 -6.613  1.00 18.26 ? 68  PHE H N    1 
ATOM   2537 C CA   . PHE B 2 68  ? 4.242   35.263 -5.791  1.00 15.84 ? 68  PHE H CA   1 
ATOM   2538 C C    . PHE B 2 68  ? 5.465   35.219 -6.694  1.00 17.88 ? 68  PHE H C    1 
ATOM   2539 O O    . PHE B 2 68  ? 5.472   34.521 -7.722  1.00 19.39 ? 68  PHE H O    1 
ATOM   2540 C CB   . PHE B 2 68  ? 4.325   34.087 -4.810  1.00 17.81 ? 68  PHE H CB   1 
ATOM   2541 C CG   . PHE B 2 68  ? 3.333   34.111 -3.685  1.00 18.50 ? 68  PHE H CG   1 
ATOM   2542 C CD1  . PHE B 2 68  ? 2.200   34.891 -3.712  1.00 20.61 ? 68  PHE H CD1  1 
ATOM   2543 C CD2  . PHE B 2 68  ? 3.483   33.233 -2.629  1.00 17.98 ? 68  PHE H CD2  1 
ATOM   2544 C CE1  . PHE B 2 68  ? 1.290   34.855 -2.665  1.00 19.31 ? 68  PHE H CE1  1 
ATOM   2545 C CE2  . PHE B 2 68  ? 2.579   33.183 -1.607  1.00 18.60 ? 68  PHE H CE2  1 
ATOM   2546 C CZ   . PHE B 2 68  ? 1.450   33.991 -1.635  1.00 22.73 ? 68  PHE H CZ   1 
ATOM   2547 H H    . PHE B 2 68  ? 2.935   34.360 -6.925  1.00 21.97 ? 68  PHE H H    1 
ATOM   2548 H HA   . PHE B 2 68  ? 4.228   36.094 -5.290  1.00 19.07 ? 68  PHE H HA   1 
ATOM   2549 H HB2  . PHE B 2 68  ? 4.180   33.266 -5.305  1.00 21.43 ? 68  PHE H HB2  1 
ATOM   2550 H HB3  . PHE B 2 68  ? 5.210   34.083 -4.413  1.00 21.43 ? 68  PHE H HB3  1 
ATOM   2551 H HD1  . PHE B 2 68  ? 2.043   35.448 -4.440  1.00 24.79 ? 68  PHE H HD1  1 
ATOM   2552 H HD2  . PHE B 2 68  ? 4.218   32.663 -2.613  1.00 21.63 ? 68  PHE H HD2  1 
ATOM   2553 H HE1  . PHE B 2 68  ? 0.561   35.433 -2.670  1.00 23.23 ? 68  PHE H HE1  1 
ATOM   2554 H HE2  . PHE B 2 68  ? 2.719   32.606 -0.890  1.00 22.38 ? 68  PHE H HE2  1 
ATOM   2555 H HZ   . PHE B 2 68  ? 0.814   33.939 -0.959  1.00 27.34 ? 68  PHE H HZ   1 
ATOM   2556 N N    . THR B 2 69  ? 6.498   35.961 -6.321  1.00 15.05 ? 69  THR H N    1 
ATOM   2557 C CA   . THR B 2 69  ? 7.756   35.925 -7.043  1.00 17.30 ? 69  THR H CA   1 
ATOM   2558 C C    . THR B 2 69  ? 8.912   35.745 -6.067  1.00 18.07 ? 69  THR H C    1 
ATOM   2559 O O    . THR B 2 69  ? 9.000   36.466 -5.064  1.00 19.47 ? 69  THR H O    1 
ATOM   2560 C CB   . THR B 2 69  ? 7.980   37.222 -7.822  1.00 21.16 ? 69  THR H CB   1 
ATOM   2561 O OG1  . THR B 2 69  ? 7.057   37.287 -8.910  1.00 29.81 ? 69  THR H OG1  1 
ATOM   2562 C CG2  . THR B 2 69  ? 9.358   37.175 -8.441  1.00 30.67 ? 69  THR H CG2  1 
ATOM   2563 H H    . THR B 2 69  ? 6.493   36.495 -5.647  1.00 18.12 ? 69  THR H H    1 
ATOM   2564 H HA   . THR B 2 69  ? 7.736   35.171 -7.653  1.00 20.82 ? 69  THR H HA   1 
ATOM   2565 H HB   . THR B 2 69  ? 7.877   37.985 -7.233  1.00 25.45 ? 69  THR H HB   1 
ATOM   2566 H HG1  . THR B 2 69  ? 7.120   38.030 -9.297  1.00 35.83 ? 69  THR H HG1  1 
ATOM   2567 H HG21 . THR B 2 69  ? 9.520   37.982 -8.953  1.00 36.87 ? 69  THR H HG21 1 
ATOM   2568 H HG22 . THR B 2 69  ? 10.031  37.103 -7.746  1.00 36.87 ? 69  THR H HG22 1 
ATOM   2569 H HG23 . THR B 2 69  ? 9.431   36.408 -9.030  1.00 36.87 ? 69  THR H HG23 1 
ATOM   2570 N N    . ILE B 2 70  ? 9.857   34.863 -6.403  1.00 15.16 ? 70  ILE H N    1 
ATOM   2571 C CA   . ILE B 2 70  ? 11.029  34.642 -5.568  1.00 15.33 ? 70  ILE H CA   1 
ATOM   2572 C C    . ILE B 2 70  ? 12.246  35.294 -6.228  1.00 14.70 ? 70  ILE H C    1 
ATOM   2573 O O    . ILE B 2 70  ? 12.384  35.363 -7.460  1.00 15.71 ? 70  ILE H O    1 
ATOM   2574 C CB   . ILE B 2 70  ? 11.293  33.139 -5.343  1.00 13.40 ? 70  ILE H CB   1 
ATOM   2575 C CG1  . ILE B 2 70  ? 12.398  32.914 -4.299  1.00 12.91 ? 70  ILE H CG1  1 
ATOM   2576 C CG2  . ILE B 2 70  ? 11.609  32.427 -6.649  1.00 13.39 ? 70  ILE H CG2  1 
ATOM   2577 C CD1  . ILE B 2 70  ? 12.547  31.376 -3.894  1.00 12.69 ? 70  ILE H CD1  1 
ATOM   2578 H H    . ILE B 2 70  ? 9.836   34.380 -7.114  1.00 18.26 ? 70  ILE H H    1 
ATOM   2579 H HA   . ILE B 2 70  ? 10.874  35.065 -4.709  1.00 18.46 ? 70  ILE H HA   1 
ATOM   2580 H HB   . ILE B 2 70  ? 10.476  32.754 -4.990  1.00 16.14 ? 70  ILE H HB   1 
ATOM   2581 H HG12 . ILE B 2 70  ? 13.245  33.213 -4.664  1.00 15.56 ? 70  ILE H HG12 1 
ATOM   2582 H HG13 . ILE B 2 70  ? 12.185  33.417 -3.497  1.00 15.56 ? 70  ILE H HG13 1 
ATOM   2583 H HG21 . ILE B 2 70  ? 11.542  31.469 -6.511  1.00 16.13 ? 70  ILE H HG21 1 
ATOM   2584 H HG22 . ILE B 2 70  ? 10.971  32.708 -7.324  1.00 16.13 ? 70  ILE H HG22 1 
ATOM   2585 H HG23 . ILE B 2 70  ? 12.508  32.660 -6.926  1.00 16.13 ? 70  ILE H HG23 1 
ATOM   2586 H HD11 . ILE B 2 70  ? 13.376  31.257 -3.404  1.00 15.29 ? 70  ILE H HD11 1 
ATOM   2587 H HD12 . ILE B 2 70  ? 11.795  31.121 -3.337  1.00 15.29 ? 70  ILE H HD12 1 
ATOM   2588 H HD13 . ILE B 2 70  ? 12.560  30.837 -4.700  1.00 15.29 ? 70  ILE H HD13 1 
ATOM   2589 N N    . SER B 2 71  ? 13.154  35.767 -5.397  1.00 14.72 ? 71  SER H N    1 
ATOM   2590 C CA   . SER B 2 71  ? 14.387  36.372 -5.845  1.00 13.63 ? 71  SER H CA   1 
ATOM   2591 C C    . SER B 2 71  ? 15.449  36.222 -4.770  1.00 14.60 ? 71  SER H C    1 
ATOM   2592 O O    . SER B 2 71  ? 15.159  35.905 -3.611  1.00 15.95 ? 71  SER H O    1 
ATOM   2593 C CB   . SER B 2 71  ? 14.140  37.822 -6.197  1.00 18.26 ? 71  SER H CB   1 
ATOM   2594 O OG   . SER B 2 71  ? 13.940  38.557 -5.012  1.00 20.43 ? 71  SER H OG   1 
ATOM   2595 H H    . SER B 2 71  ? 13.076  35.749 -4.541  1.00 17.73 ? 71  SER H H    1 
ATOM   2596 H HA   . SER B 2 71  ? 14.732  35.913 -6.626  1.00 16.41 ? 71  SER H HA   1 
ATOM   2597 H HB2  . SER B 2 71  ? 14.910  38.175 -6.670  1.00 21.98 ? 71  SER H HB2  1 
ATOM   2598 H HB3  . SER B 2 71  ? 13.349  37.888 -6.755  1.00 21.98 ? 71  SER H HB3  1 
ATOM   2599 H HG   . SER B 2 71  ? 13.874  39.376 -5.190  1.00 24.58 ? 71  SER H HG   1 
ATOM   2600 N N    . ARG B 2 72  ? 16.687  36.417 -5.171  1.00 12.80 ? 72  ARG H N    1 
ATOM   2601 C CA   . ARG B 2 72  ? 17.790  36.320 -4.233  1.00 16.01 ? 72  ARG H CA   1 
ATOM   2602 C C    . ARG B 2 72  ? 18.816  37.371 -4.588  1.00 18.12 ? 72  ARG H C    1 
ATOM   2603 O O    . ARG B 2 72  ? 18.966  37.765 -5.751  1.00 18.17 ? 72  ARG H O    1 
ATOM   2604 C CB   . ARG B 2 72  ? 18.465  34.927 -4.204  1.00 13.41 ? 72  ARG H CB   1 
ATOM   2605 C CG   . ARG B 2 72  ? 19.186  34.474 -5.439  1.00 15.56 ? 72  ARG H CG   1 
ATOM   2606 C CD   . ARG B 2 72  ? 19.463  32.994 -5.448  1.00 16.11 ? 72  ARG H CD   1 
ATOM   2607 N NE   . ARG B 2 72  ? 20.437  32.654 -4.406  1.00 15.29 ? 72  ARG H NE   1 
ATOM   2608 C CZ   . ARG B 2 72  ? 20.579  31.431 -3.916  1.00 15.20 ? 72  ARG H CZ   1 
ATOM   2609 N NH1  . ARG B 2 72  ? 19.913  30.400 -4.440  1.00 14.53 ? 72  ARG H NH1  1 
ATOM   2610 N NH2  . ARG B 2 72  ? 21.436  31.224 -2.919  1.00 16.67 ? 72  ARG H NH2  1 
ATOM   2611 H H    . ARG B 2 72  ? 16.916  36.607 -5.978  1.00 15.42 ? 72  ARG H H    1 
ATOM   2612 H HA   . ARG B 2 72  ? 17.443  36.484 -3.343  1.00 19.27 ? 72  ARG H HA   1 
ATOM   2613 H HB2  . ARG B 2 72  ? 19.117  34.929 -3.486  1.00 16.15 ? 72  ARG H HB2  1 
ATOM   2614 H HB3  . ARG B 2 72  ? 17.777  34.268 -4.025  1.00 16.15 ? 72  ARG H HB3  1 
ATOM   2615 H HG2  . ARG B 2 72  ? 18.643  34.681 -6.216  1.00 18.73 ? 72  ARG H HG2  1 
ATOM   2616 H HG3  . ARG B 2 72  ? 20.037  34.937 -5.496  1.00 18.73 ? 72  ARG H HG3  1 
ATOM   2617 H HD2  . ARG B 2 72  ? 18.641  32.508 -5.276  1.00 19.39 ? 72  ARG H HD2  1 
ATOM   2618 H HD3  . ARG B 2 72  ? 19.827  32.736 -6.309  1.00 19.39 ? 72  ARG H HD3  1 
ATOM   2619 H HE   . ARG B 2 72  ? 20.940  33.280 -4.097  1.00 18.41 ? 72  ARG H HE   1 
ATOM   2620 H HH11 . ARG B 2 72  ? 19.382  30.524 -5.105  1.00 17.50 ? 72  ARG H HH11 1 
ATOM   2621 H HH12 . ARG B 2 72  ? 20.015  29.611 -4.113  1.00 17.50 ? 72  ARG H HH12 1 
ATOM   2622 H HH21 . ARG B 2 72  ? 21.890  31.881 -2.599  1.00 20.06 ? 72  ARG H HH21 1 
ATOM   2623 H HH22 . ARG B 2 72  ? 21.535  30.434 -2.595  1.00 20.06 ? 72  ARG H HH22 1 
ATOM   2624 N N    . ASP B 2 73  ? 19.535  37.814 -3.570  1.00 18.03 ? 73  ASP H N    1 
ATOM   2625 C CA   . ASP B 2 73  ? 20.625  38.752 -3.782  1.00 21.95 ? 73  ASP H CA   1 
ATOM   2626 C C    . ASP B 2 73  ? 21.858  38.099 -3.174  1.00 18.66 ? 73  ASP H C    1 
ATOM   2627 O O    . ASP B 2 73  ? 21.931  37.906 -1.952  1.00 21.60 ? 73  ASP H O    1 
ATOM   2628 C CB   . ASP B 2 73  ? 20.264  40.095 -3.160  1.00 21.41 ? 73  ASP H CB   1 
ATOM   2629 C CG   . ASP B 2 73  ? 21.404  41.086 -3.190  1.00 30.67 ? 73  ASP H CG   1 
ATOM   2630 O OD1  . ASP B 2 73  ? 22.556  40.699 -3.447  1.00 26.46 ? 73  ASP H OD1  1 
ATOM   2631 O OD2  . ASP B 2 73  ? 21.107  42.280 -3.005  1.00 26.55 ? 73  ASP H OD2  1 
ATOM   2632 H H    . ASP B 2 73  ? 19.411  37.587 -2.750  1.00 21.70 ? 73  ASP H H    1 
ATOM   2633 H HA   . ASP B 2 73  ? 20.814  38.918 -4.719  1.00 26.40 ? 73  ASP H HA   1 
ATOM   2634 H HB2  . ASP B 2 73  ? 19.520  40.480 -3.650  1.00 25.75 ? 73  ASP H HB2  1 
ATOM   2635 H HB3  . ASP B 2 73  ? 20.013  39.956 -2.233  1.00 25.75 ? 73  ASP H HB3  1 
ATOM   2636 N N    . ASN B 2 74  ? 22.761  37.631 -4.031  1.00 19.07 ? 74  ASN H N    1 
ATOM   2637 C CA   . ASN B 2 74  ? 23.925  36.890 -3.565  1.00 21.89 ? 74  ASN H CA   1 
ATOM   2638 C C    . ASN B 2 74  ? 25.050  37.788 -3.105  1.00 24.18 ? 74  ASN H C    1 
ATOM   2639 O O    . ASN B 2 74  ? 26.056  37.269 -2.619  1.00 26.04 ? 74  ASN H O    1 
ATOM   2640 C CB   . ASN B 2 74  ? 24.445  35.936 -4.629  1.00 21.68 ? 74  ASN H CB   1 
ATOM   2641 C CG   . ASN B 2 74  ? 23.523  34.728 -4.807  1.00 24.32 ? 74  ASN H CG   1 
ATOM   2642 O OD1  . ASN B 2 74  ? 22.600  34.520 -4.016  1.00 17.47 ? 74  ASN H OD1  1 
ATOM   2643 N ND2  . ASN B 2 74  ? 23.732  33.987 -5.849  1.00 19.90 ? 74  ASN H ND2  1 
ATOM   2644 H H    . ASN B 2 74  ? 22.721  37.730 -4.884  1.00 22.94 ? 74  ASN H H    1 
ATOM   2645 H HA   . ASN B 2 74  ? 23.639  36.347 -2.814  1.00 26.33 ? 74  ASN H HA   1 
ATOM   2646 H HB2  . ASN B 2 74  ? 24.501  36.403 -5.478  1.00 26.08 ? 74  ASN H HB2  1 
ATOM   2647 H HB3  . ASN B 2 74  ? 25.322  35.614 -4.370  1.00 26.08 ? 74  ASN H HB3  1 
ATOM   2648 H HD21 . ASN B 2 74  ? 23.240  33.296 -5.992  1.00 23.94 ? 74  ASN H HD21 1 
ATOM   2649 H HD22 . ASN B 2 74  ? 24.364  34.186 -6.398  1.00 23.94 ? 74  ASN H HD22 1 
ATOM   2650 N N    . SER B 2 75  ? 24.918  39.104 -3.248  1.00 28.95 ? 75  SER H N    1 
ATOM   2651 C CA   . SER B 2 75  ? 25.949  39.963 -2.686  1.00 31.72 ? 75  SER H CA   1 
ATOM   2652 C C    . SER B 2 75  ? 25.662  40.236 -1.219  1.00 30.26 ? 75  SER H C    1 
ATOM   2653 O O    . SER B 2 75  ? 26.589  40.274 -0.405  1.00 37.73 ? 75  SER H O    1 
ATOM   2654 C CB   . SER B 2 75  ? 26.073  41.236 -3.523  1.00 29.34 ? 75  SER H CB   1 
ATOM   2655 O OG   . SER B 2 75  ? 24.905  42.019 -3.464  1.00 37.01 ? 75  SER H OG   1 
ATOM   2656 H H    . SER B 2 75  ? 24.270  39.504 -3.648  1.00 34.80 ? 75  SER H H    1 
ATOM   2657 H HA   . SER B 2 75  ? 26.822  39.543 -2.730  1.00 38.13 ? 75  SER H HA   1 
ATOM   2658 H HB2  . SER B 2 75  ? 26.816  41.760 -3.186  1.00 35.27 ? 75  SER H HB2  1 
ATOM   2659 H HB3  . SER B 2 75  ? 26.235  40.988 -4.447  1.00 35.27 ? 75  SER H HB3  1 
ATOM   2660 H HG   . SER B 2 75  ? 24.274  41.623 -3.852  1.00 44.47 ? 75  SER H HG   1 
ATOM   2661 N N    . LYS B 2 76  ? 24.395  40.331 -0.835  1.00 25.72 ? 76  LYS H N    1 
ATOM   2662 C CA   . LYS B 2 76  ? 24.055  40.552 0.564   1.00 29.43 ? 76  LYS H CA   1 
ATOM   2663 C C    . LYS B 2 76  ? 23.467  39.312 1.239   1.00 24.76 ? 76  LYS H C    1 
ATOM   2664 O O    . LYS B 2 76  ? 23.099  39.368 2.426   1.00 25.83 ? 76  LYS H O    1 
ATOM   2665 C CB   . LYS B 2 76  ? 23.114  41.756 0.680   1.00 42.07 ? 76  LYS H CB   1 
ATOM   2666 C CG   . LYS B 2 76  ? 21.732  41.599 0.153   1.00 36.98 ? 76  LYS H CG   1 
ATOM   2667 C CD   . LYS B 2 76  ? 20.928  42.944 0.287   1.00 45.96 ? 76  LYS H CD   1 
ATOM   2668 C CE   . LYS B 2 76  ? 21.202  43.699 1.612   1.00 43.66 ? 76  LYS H CE   1 
ATOM   2669 H H    . LYS B 2 76  ? 23.719  40.272 -1.363  1.00 30.92 ? 76  LYS H H    1 
ATOM   2670 H HA   . LYS B 2 76  ? 24.857  40.773 1.062   1.00 35.38 ? 76  LYS H HA   1 
ATOM   2671 H HB2  . LYS B 2 76  ? 23.031  41.980 1.620   1.00 50.54 ? 76  LYS H HB2  1 
ATOM   2672 H HB3  . LYS B 2 76  ? 23.515  42.495 0.197   1.00 50.54 ? 76  LYS H HB3  1 
ATOM   2673 H HG2  . LYS B 2 76  ? 21.769  41.354 -0.784  1.00 44.43 ? 76  LYS H HG2  1 
ATOM   2674 H HG3  . LYS B 2 76  ? 21.269  40.912 0.658   1.00 44.43 ? 76  LYS H HG3  1 
ATOM   2675 H HD2  . LYS B 2 76  ? 21.174  43.532 -0.444  1.00 55.22 ? 76  LYS H HD2  1 
ATOM   2676 H HD3  . LYS B 2 76  ? 19.979  42.748 0.249   1.00 55.22 ? 76  LYS H HD3  1 
ATOM   2677 N N    . ASN B 2 77  ? 23.422  38.185 0.532   1.00 20.91 ? 77  ASN H N    1 
ATOM   2678 C CA   . ASN B 2 77  ? 23.046  36.900 1.120   1.00 19.51 ? 77  ASN H CA   1 
ATOM   2679 C C    . ASN B 2 77  ? 21.651  36.968 1.734   1.00 18.19 ? 77  ASN H C    1 
ATOM   2680 O O    . ASN B 2 77  ? 21.428  36.665 2.915   1.00 19.13 ? 77  ASN H O    1 
ATOM   2681 C CB   . ASN B 2 77  ? 24.093  36.423 2.137   1.00 19.50 ? 77  ASN H CB   1 
ATOM   2682 C CG   . ASN B 2 77  ? 25.461  36.358 1.534   1.00 29.82 ? 77  ASN H CG   1 
ATOM   2683 O OD1  . ASN B 2 77  ? 25.656  35.652 0.556   1.00 28.58 ? 77  ASN H OD1  1 
ATOM   2684 N ND2  . ASN B 2 77  ? 26.419  37.089 2.101   1.00 28.42 ? 77  ASN H ND2  1 
ATOM   2685 H H    . ASN B 2 77  ? 23.609  38.137 -0.306  1.00 25.15 ? 77  ASN H H    1 
ATOM   2686 H HA   . ASN B 2 77  ? 23.013  36.240 0.409   1.00 23.48 ? 77  ASN H HA   1 
ATOM   2687 H HB2  . ASN B 2 77  ? 24.118  37.042 2.883   1.00 23.46 ? 77  ASN H HB2  1 
ATOM   2688 H HB3  . ASN B 2 77  ? 23.855  35.536 2.449   1.00 23.46 ? 77  ASN H HB3  1 
ATOM   2689 H HD21 . ASN B 2 77  ? 27.217  37.074 1.780   1.00 34.17 ? 77  ASN H HD21 1 
ATOM   2690 H HD22 . ASN B 2 77  ? 26.241  37.575 2.787   1.00 34.17 ? 77  ASN H HD22 1 
ATOM   2691 N N    . THR B 2 78  ? 20.694  37.337 0.884   1.00 17.53 ? 78  THR H N    1 
ATOM   2692 C CA   . THR B 2 78  ? 19.297  37.439 1.254   1.00 19.28 ? 78  THR H CA   1 
ATOM   2693 C C    . THR B 2 78  ? 18.423  36.785 0.200   1.00 18.16 ? 78  THR H C    1 
ATOM   2694 O O    . THR B 2 78  ? 18.686  36.911 -1.007  1.00 18.66 ? 78  THR H O    1 
ATOM   2695 C CB   . THR B 2 78  ? 18.914  38.918 1.414   1.00 22.38 ? 78  THR H CB   1 
ATOM   2696 O OG1  . THR B 2 78  ? 19.952  39.554 2.178   1.00 28.30 ? 78  THR H OG1  1 
ATOM   2697 C CG2  . THR B 2 78  ? 17.569  39.081 2.095   1.00 21.45 ? 78  THR H CG2  1 
ATOM   2698 H H    . THR B 2 78  ? 20.841  37.538 0.061   1.00 21.10 ? 78  THR H H    1 
ATOM   2699 H HA   . THR B 2 78  ? 19.135  36.968 2.087   1.00 23.20 ? 78  THR H HA   1 
ATOM   2700 H HB   . THR B 2 78  ? 18.826  39.341 0.546   1.00 26.91 ? 78  THR H HB   1 
ATOM   2701 H HG1  . THR B 2 78  ? 19.773  40.368 2.284   1.00 34.02 ? 78  THR H HG1  1 
ATOM   2702 H HG21 . THR B 2 78  ? 17.384  40.021 2.242   1.00 25.80 ? 78  THR H HG21 1 
ATOM   2703 H HG22 . THR B 2 78  ? 16.869  38.704 1.539   1.00 25.80 ? 78  THR H HG22 1 
ATOM   2704 H HG23 . THR B 2 78  ? 17.573  38.623 2.950   1.00 25.80 ? 78  THR H HG23 1 
ATOM   2705 N N    . LEU B 2 79  ? 17.392  36.088 0.686   1.00 16.32 ? 79  LEU H N    1 
ATOM   2706 C CA   . LEU B 2 79  ? 16.315  35.531 -0.123  1.00 17.49 ? 79  LEU H CA   1 
ATOM   2707 C C    . LEU B 2 79  ? 15.055  36.352 0.120   1.00 15.41 ? 79  LEU H C    1 
ATOM   2708 O O    . LEU B 2 79  ? 14.803  36.781 1.251   1.00 17.30 ? 79  LEU H O    1 
ATOM   2709 C CB   . LEU B 2 79  ? 16.038  34.076 0.281   1.00 15.73 ? 79  LEU H CB   1 
ATOM   2710 C CG   . LEU B 2 79  ? 15.017  33.279 -0.531  1.00 16.76 ? 79  LEU H CG   1 
ATOM   2711 C CD1  . LEU B 2 79  ? 15.569  32.957 -1.883  1.00 16.79 ? 79  LEU H CD1  1 
ATOM   2712 C CD2  . LEU B 2 79  ? 14.528  32.029 0.258   1.00 16.34 ? 79  LEU H CD2  1 
ATOM   2713 H H    . LEU B 2 79  ? 17.293  35.919 1.523   1.00 19.65 ? 79  LEU H H    1 
ATOM   2714 H HA   . LEU B 2 79  ? 16.551  35.558 -1.063  1.00 21.05 ? 79  LEU H HA   1 
ATOM   2715 H HB2  . LEU B 2 79  ? 16.876  33.591 0.223   1.00 18.94 ? 79  LEU H HB2  1 
ATOM   2716 H HB3  . LEU B 2 79  ? 15.720  34.082 1.197   1.00 18.94 ? 79  LEU H HB3  1 
ATOM   2717 H HG   . LEU B 2 79  ? 14.222  33.814 -0.681  1.00 20.17 ? 79  LEU H HG   1 
ATOM   2718 H HD11 . LEU B 2 79  ? 14.957  32.358 -2.340  1.00 20.21 ? 79  LEU H HD11 1 
ATOM   2719 H HD12 . LEU B 2 79  ? 15.666  33.779 -2.389  1.00 20.21 ? 79  LEU H HD12 1 
ATOM   2720 H HD13 . LEU B 2 79  ? 16.433  32.529 -1.778  1.00 20.21 ? 79  LEU H HD13 1 
ATOM   2721 H HD21 . LEU B 2 79  ? 13.990  31.476 -0.330  1.00 19.66 ? 79  LEU H HD21 1 
ATOM   2722 H HD22 . LEU B 2 79  ? 15.300  31.530 0.568   1.00 19.66 ? 79  LEU H HD22 1 
ATOM   2723 H HD23 . LEU B 2 79  ? 13.997  32.321 1.015   1.00 19.66 ? 79  LEU H HD23 1 
ATOM   2724 N N    . TYR B 2 80  ? 14.247  36.570 -0.935  1.00 12.62 ? 80  TYR H N    1 
ATOM   2725 C CA   . TYR B 2 80  ? 13.020  37.341 -0.855  1.00 14.86 ? 80  TYR H CA   1 
ATOM   2726 C C    . TYR B 2 80  ? 11.836  36.562 -1.400  1.00 16.78 ? 80  TYR H C    1 
ATOM   2727 O O    . TYR B 2 80  ? 11.965  35.709 -2.287  1.00 17.11 ? 80  TYR H O    1 
ATOM   2728 C CB   . TYR B 2 80  ? 13.115  38.650 -1.643  1.00 15.25 ? 80  TYR H CB   1 
ATOM   2729 C CG   . TYR B 2 80  ? 14.284  39.499 -1.247  1.00 17.88 ? 80  TYR H CG   1 
ATOM   2730 C CD1  . TYR B 2 80  ? 14.253  40.218 -0.063  1.00 24.11 ? 80  TYR H CD1  1 
ATOM   2731 C CD2  . TYR B 2 80  ? 15.394  39.606 -2.036  1.00 18.09 ? 80  TYR H CD2  1 
ATOM   2732 C CE1  . TYR B 2 80  ? 15.299  41.005 0.323   1.00 22.76 ? 80  TYR H CE1  1 
ATOM   2733 C CE2  . TYR B 2 80  ? 16.454  40.408 -1.667  1.00 23.42 ? 80  TYR H CE2  1 
ATOM   2734 C CZ   . TYR B 2 80  ? 16.381  41.113 -0.483  1.00 23.67 ? 80  TYR H CZ   1 
ATOM   2735 O OH   . TYR B 2 80  ? 17.415  41.918 -0.096  1.00 29.96 ? 80  TYR H OH   1 
ATOM   2736 H H    . TYR B 2 80  ? 14.404  36.267 -1.724  1.00 15.21 ? 80  TYR H H    1 
ATOM   2737 H HA   . TYR B 2 80  ? 12.862  37.528 0.084   1.00 17.89 ? 80  TYR H HA   1 
ATOM   2738 H HB2  . TYR B 2 80  ? 13.203  38.443 -2.587  1.00 18.36 ? 80  TYR H HB2  1 
ATOM   2739 H HB3  . TYR B 2 80  ? 12.307  39.166 -1.492  1.00 18.36 ? 80  TYR H HB3  1 
ATOM   2740 H HD1  . TYR B 2 80  ? 13.501  40.164 0.482   1.00 28.99 ? 80  TYR H HD1  1 
ATOM   2741 H HD2  . TYR B 2 80  ? 15.435  39.130 -2.834  1.00 21.77 ? 80  TYR H HD2  1 
ATOM   2742 H HE1  . TYR B 2 80  ? 15.269  41.462 1.132   1.00 27.37 ? 80  TYR H HE1  1 
ATOM   2743 H HE2  . TYR B 2 80  ? 17.207  40.472 -2.209  1.00 28.17 ? 80  TYR H HE2  1 
ATOM   2744 H HH   . TYR B 2 80  ? 18.002  41.939 -0.696  1.00 36.01 ? 80  TYR H HH   1 
ATOM   2745 N N    . LEU B 2 81  ? 10.671  36.878 -0.870  1.00 15.89 ? 81  LEU H N    1 
ATOM   2746 C CA   . LEU B 2 81  ? 9.403   36.406 -1.391  1.00 15.88 ? 81  LEU H CA   1 
ATOM   2747 C C    . LEU B 2 81  ? 8.495   37.602 -1.561  1.00 18.71 ? 81  LEU H C    1 
ATOM   2748 O O    . LEU B 2 81  ? 8.095   38.240 -0.572  1.00 16.36 ? 81  LEU H O    1 
ATOM   2749 C CB   . LEU B 2 81  ? 8.735   35.378 -0.480  1.00 16.32 ? 81  LEU H CB   1 
ATOM   2750 C CG   . LEU B 2 81  ? 7.438   34.769 -1.056  1.00 19.49 ? 81  LEU H CG   1 
ATOM   2751 C CD1  . LEU B 2 81  ? 7.710   34.021 -2.352  1.00 18.77 ? 81  LEU H CD1  1 
ATOM   2752 C CD2  . LEU B 2 81  ? 6.720   33.858 -0.058  1.00 19.94 ? 81  LEU H CD2  1 
ATOM   2753 H H    . LEU B 2 81  ? 10.585  37.385 -0.181  1.00 19.13 ? 81  LEU H H    1 
ATOM   2754 H HA   . LEU B 2 81  ? 9.566   35.985 -2.249  1.00 19.12 ? 81  LEU H HA   1 
ATOM   2755 H HB2  . LEU B 2 81  ? 9.358   34.651 -0.325  1.00 19.64 ? 81  LEU H HB2  1 
ATOM   2756 H HB3  . LEU B 2 81  ? 8.510   35.808 0.360   1.00 19.64 ? 81  LEU H HB3  1 
ATOM   2757 H HG   . LEU B 2 81  ? 6.839   35.508 -1.247  1.00 23.45 ? 81  LEU H HG   1 
ATOM   2758 H HD11 . LEU B 2 81  ? 6.876   33.655 -2.687  1.00 22.59 ? 81  LEU H HD11 1 
ATOM   2759 H HD12 . LEU B 2 81  ? 8.084   34.638 -3.001  1.00 22.59 ? 81  LEU H HD12 1 
ATOM   2760 H HD13 . LEU B 2 81  ? 8.338   33.303 -2.177  1.00 22.59 ? 81  LEU H HD13 1 
ATOM   2761 H HD21 . LEU B 2 81  ? 5.867   33.589 -0.433  1.00 23.99 ? 81  LEU H HD21 1 
ATOM   2762 H HD22 . LEU B 2 81  ? 7.269   33.076 0.108   1.00 23.99 ? 81  LEU H HD22 1 
ATOM   2763 H HD23 . LEU B 2 81  ? 6.579   34.345 0.769   1.00 23.99 ? 81  LEU H HD23 1 
ATOM   2764 N N    . GLN B 2 82  ? 8.216   37.933 -2.810  1.00 16.65 ? 82  GLN H N    1 
ATOM   2765 C CA   . GLN B 2 82  ? 7.269   38.986 -3.133  1.00 17.45 ? 82  GLN H CA   1 
ATOM   2766 C C    . GLN B 2 82  ? 5.897   38.349 -3.340  1.00 17.82 ? 82  GLN H C    1 
ATOM   2767 O O    . GLN B 2 82  ? 5.678   37.619 -4.306  1.00 17.46 ? 82  GLN H O    1 
ATOM   2768 C CB   . GLN B 2 82  ? 7.715   39.778 -4.360  1.00 20.21 ? 82  GLN H CB   1 
ATOM   2769 C CG   . GLN B 2 82  ? 6.798   40.917 -4.739  1.00 22.91 ? 82  GLN H CG   1 
ATOM   2770 C CD   . GLN B 2 82  ? 6.648   41.952 -3.668  1.00 24.16 ? 82  GLN H CD   1 
ATOM   2771 O OE1  . GLN B 2 82  ? 7.623   42.601 -3.265  1.00 25.10 ? 82  GLN H OE1  1 
ATOM   2772 N NE2  . GLN B 2 82  ? 5.423   42.127 -3.199  1.00 24.86 ? 82  GLN H NE2  1 
ATOM   2773 H H    . GLN B 2 82  ? 8.569   37.557 -3.498  1.00 20.04 ? 82  GLN H H    1 
ATOM   2774 H HA   . GLN B 2 82  ? 7.211   39.607 -2.390  1.00 21.01 ? 82  GLN H HA   1 
ATOM   2775 H HB2  . GLN B 2 82  ? 8.591   40.154 -4.183  1.00 24.32 ? 82  GLN H HB2  1 
ATOM   2776 H HB3  . GLN B 2 82  ? 7.760   39.174 -5.118  1.00 24.32 ? 82  GLN H HB3  1 
ATOM   2777 H HG2  . GLN B 2 82  ? 7.154   41.356 -5.527  1.00 27.56 ? 82  GLN H HG2  1 
ATOM   2778 H HG3  . GLN B 2 82  ? 5.917   40.558 -4.929  1.00 27.56 ? 82  GLN H HG3  1 
ATOM   2779 H HE21 . GLN B 2 82  ? 4.773   41.658 -3.510  1.00 29.89 ? 82  GLN H HE21 1 
ATOM   2780 H HE22 . GLN B 2 82  ? 5.278   42.709 -2.583  1.00 29.89 ? 82  GLN H HE22 1 
ATOM   2781 N N    . MET B 2 83  ? 4.971   38.654 -2.440  1.00 15.41 ? 83  MET H N    1 
ATOM   2782 C CA   . MET B 2 83  ? 3.640   38.089 -2.430  1.00 20.64 ? 83  MET H CA   1 
ATOM   2783 C C    . MET B 2 83  ? 2.687   39.161 -2.947  1.00 22.46 ? 83  MET H C    1 
ATOM   2784 O O    . MET B 2 83  ? 2.657   40.278 -2.425  1.00 25.18 ? 83  MET H O    1 
ATOM   2785 C CB   . MET B 2 83  ? 3.218   37.646 -1.000  1.00 21.61 ? 83  MET H CB   1 
ATOM   2786 C CG   . MET B 2 83  ? 4.342   37.011 -0.261  1.00 24.26 ? 83  MET H CG   1 
ATOM   2787 S SD   . MET B 2 83  ? 3.883   36.710 1.529   1.00 28.82 ? 83  MET H SD   1 
ATOM   2788 C CE   . MET B 2 83  ? 3.139   35.184 1.212   1.00 22.60 ? 83  MET H CE   1 
ATOM   2789 H H    . MET B 2 83  ? 5.101   39.212 -1.798  1.00 18.55 ? 83  MET H H    1 
ATOM   2790 H HA   . MET B 2 83  ? 3.609   37.298 -2.991  1.00 24.83 ? 83  MET H HA   1 
ATOM   2791 H HB2  . MET B 2 83  ? 2.925   38.423 -0.498  1.00 26.00 ? 83  MET H HB2  1 
ATOM   2792 H HB3  . MET B 2 83  ? 2.495   37.002 -1.065  1.00 26.00 ? 83  MET H HB3  1 
ATOM   2793 H HG2  . MET B 2 83  ? 4.557   36.158 -0.670  1.00 29.17 ? 83  MET H HG2  1 
ATOM   2794 H HG3  . MET B 2 83  ? 5.116   37.595 -0.286  1.00 29.17 ? 83  MET H HG3  1 
ATOM   2795 H HE1  . MET B 2 83  ? 2.762   34.839 2.037   1.00 27.19 ? 83  MET H HE1  1 
ATOM   2796 H HE2  . MET B 2 83  ? 2.438   35.305 0.553   1.00 27.19 ? 83  MET H HE2  1 
ATOM   2797 H HE3  . MET B 2 83  ? 3.809   34.570 0.873   1.00 27.19 ? 83  MET H HE3  1 
ATOM   2798 N N    . ASN B 2 84  ? 1.936   38.824 -3.994  1.00 24.84 ? 84  ASN H N    1 
ATOM   2799 C CA   . ASN B 2 84  ? 0.906   39.710 -4.508  1.00 29.62 ? 84  ASN H CA   1 
ATOM   2800 C C    . ASN B 2 84  ? -0.419  38.967 -4.504  1.00 33.10 ? 84  ASN H C    1 
ATOM   2801 O O    . ASN B 2 84  ? -0.479  37.729 -4.366  1.00 43.17 ? 84  ASN H O    1 
ATOM   2802 C CB   . ASN B 2 84  ? 1.266   40.244 -5.910  1.00 26.00 ? 84  ASN H CB   1 
ATOM   2803 C CG   . ASN B 2 84  ? 2.674   40.741 -5.982  1.00 30.27 ? 84  ASN H CG   1 
ATOM   2804 O OD1  . ASN B 2 84  ? 3.029   41.739 -5.358  1.00 44.54 ? 84  ASN H OD1  1 
ATOM   2805 N ND2  . ASN B 2 84  ? 3.514   39.999 -6.727  1.00 44.20 ? 84  ASN H ND2  1 
ATOM   2806 H H    . ASN B 2 84  ? 2.008   38.082 -4.423  1.00 29.87 ? 84  ASN H H    1 
ATOM   2807 H HA   . ASN B 2 84  ? 0.809   40.484 -3.932  1.00 35.60 ? 84  ASN H HA   1 
ATOM   2808 H HB2  . ASN B 2 84  ? 1.164   39.530 -6.559  1.00 31.26 ? 84  ASN H HB2  1 
ATOM   2809 H HB3  . ASN B 2 84  ? 0.675   40.981 -6.132  1.00 31.26 ? 84  ASN H HB3  1 
ATOM   2810 H HD21 . ASN B 2 84  ? 3.227   39.292 -7.123  1.00 53.10 ? 84  ASN H HD21 1 
ATOM   2811 H HD22 . ASN B 2 84  ? 4.337   40.233 -6.807  1.00 53.10 ? 84  ASN H HD22 1 
ATOM   2812 N N    . SER B 2 85  ? -1.479  39.760 -4.688  1.00 31.81 ? 85  SER H N    1 
ATOM   2813 C CA   . SER B 2 85  ? -2.838  39.220 -4.795  1.00 22.43 ? 85  SER H CA   1 
ATOM   2814 C C    . SER B 2 85  ? -3.108  38.198 -3.675  1.00 17.74 ? 85  SER H C    1 
ATOM   2815 O O    . SER B 2 85  ? -3.639  37.110 -3.901  1.00 20.80 ? 85  SER H O    1 
ATOM   2816 C CB   . SER B 2 85  ? -3.084  38.574 -6.156  1.00 22.92 ? 85  SER H CB   1 
ATOM   2817 O OG   . SER B 2 85  ? -2.920  39.540 -7.171  1.00 31.81 ? 85  SER H OG   1 
ATOM   2818 H H    . SER B 2 85  ? -1.436  40.616 -4.754  1.00 38.24 ? 85  SER H H    1 
ATOM   2819 H HA   . SER B 2 85  ? -3.455  39.962 -4.698  1.00 26.98 ? 85  SER H HA   1 
ATOM   2820 H HB2  . SER B 2 85  ? -2.446  37.856 -6.290  1.00 27.57 ? 85  SER H HB2  1 
ATOM   2821 H HB3  . SER B 2 85  ? -3.988  38.225 -6.187  1.00 27.57 ? 85  SER H HB3  1 
ATOM   2822 H HG   . SER B 2 85  ? -2.166  39.904 -7.103  1.00 38.23 ? 85  SER H HG   1 
ATOM   2823 N N    . LEU B 2 86  ? -2.718  38.584 -2.463  1.00 22.17 ? 86  LEU H N    1 
ATOM   2824 C CA   . LEU B 2 86  ? -2.863  37.676 -1.337  1.00 20.14 ? 86  LEU H CA   1 
ATOM   2825 C C    . LEU B 2 86  ? -4.330  37.336 -1.069  1.00 23.76 ? 86  LEU H C    1 
ATOM   2826 O O    . LEU B 2 86  ? -5.262  38.143 -1.287  1.00 25.29 ? 86  LEU H O    1 
ATOM   2827 C CB   . LEU B 2 86  ? -2.211  38.280 -0.091  1.00 19.72 ? 86  LEU H CB   1 
ATOM   2828 C CG   . LEU B 2 86  ? -0.682  38.131 -0.195  1.00 20.94 ? 86  LEU H CG   1 
ATOM   2829 C CD1  . LEU B 2 86  ? -0.036  39.057 0.776   1.00 22.46 ? 86  LEU H CD1  1 
ATOM   2830 C CD2  . LEU B 2 86  ? -0.308  36.665 0.094   1.00 21.52 ? 86  LEU H CD2  1 
ATOM   2831 H H    . LEU B 2 86  ? -2.375  39.350 -2.274  1.00 26.66 ? 86  LEU H H    1 
ATOM   2832 H HA   . LEU B 2 86  ? -2.413  36.841 -1.542  1.00 24.23 ? 86  LEU H HA   1 
ATOM   2833 H HB2  . LEU B 2 86  ? -2.433  39.223 -0.029  1.00 23.73 ? 86  LEU H HB2  1 
ATOM   2834 H HB3  . LEU B 2 86  ? -2.521  37.814 0.701   1.00 23.73 ? 86  LEU H HB3  1 
ATOM   2835 H HG   . LEU B 2 86  ? -0.362  38.358 -1.083  1.00 25.18 ? 86  LEU H HG   1 
ATOM   2836 H HD11 . LEU B 2 86  ? 0.924   38.919 0.753   1.00 27.01 ? 86  LEU H HD11 1 
ATOM   2837 H HD12 . LEU B 2 86  ? -0.244  39.971 0.527   1.00 27.01 ? 86  LEU H HD12 1 
ATOM   2838 H HD13 . LEU B 2 86  ? -0.376  38.870 1.665   1.00 27.01 ? 86  LEU H HD13 1 
ATOM   2839 H HD21 . LEU B 2 86  ? 0.629   36.621 0.340   1.00 25.89 ? 86  LEU H HD21 1 
ATOM   2840 H HD22 . LEU B 2 86  ? -0.858  36.337 0.823   1.00 25.89 ? 86  LEU H HD22 1 
ATOM   2841 H HD23 . LEU B 2 86  ? -0.466  36.136 -0.704  1.00 25.89 ? 86  LEU H HD23 1 
ATOM   2842 N N    . ARG B 2 87  ? -4.510  36.103 -0.589  1.00 18.71 ? 87  ARG H N    1 
ATOM   2843 C CA   . ARG B 2 87  ? -5.818  35.588 -0.248  1.00 21.54 ? 87  ARG H CA   1 
ATOM   2844 C C    . ARG B 2 87  ? -5.819  34.990 1.153   1.00 24.23 ? 87  ARG H C    1 
ATOM   2845 O O    . ARG B 2 87  ? -4.765  34.704 1.732   1.00 19.10 ? 87  ARG H O    1 
ATOM   2846 C CB   . ARG B 2 87  ? -6.249  34.513 -1.228  1.00 23.97 ? 87  ARG H CB   1 
ATOM   2847 C CG   . ARG B 2 87  ? -6.100  34.948 -2.701  1.00 25.69 ? 87  ARG H CG   1 
ATOM   2848 C CD   . ARG B 2 87  ? -6.559  33.885 -3.696  1.00 28.07 ? 87  ARG H CD   1 
ATOM   2849 N NE   . ARG B 2 87  ? -7.896  33.387 -3.421  1.00 31.69 ? 87  ARG H NE   1 
ATOM   2850 C CZ   . ARG B 2 87  ? -8.940  33.721 -4.150  1.00 31.35 ? 87  ARG H CZ   1 
ATOM   2851 N NH1  . ARG B 2 87  ? -8.871  34.713 -5.016  1.00 29.92 ? 87  ARG H NH1  1 
ATOM   2852 N NH2  . ARG B 2 87  ? -10.113 33.161 -3.896  1.00 33.18 ? 87  ARG H NH2  1 
ATOM   2853 H H    . ARG B 2 87  ? -3.872  35.543 -0.454  1.00 22.51 ? 87  ARG H H    1 
ATOM   2854 H HA   . ARG B 2 87  ? -6.449  36.325 -0.260  1.00 25.91 ? 87  ARG H HA   1 
ATOM   2855 H HB2  . ARG B 2 87  ? -5.701  33.725 -1.091  1.00 28.83 ? 87  ARG H HB2  1 
ATOM   2856 H HB3  . ARG B 2 87  ? -7.182  34.300 -1.071  1.00 28.83 ? 87  ARG H HB3  1 
ATOM   2857 H HG2  . ARG B 2 87  ? -6.635  35.744 -2.849  1.00 30.88 ? 87  ARG H HG2  1 
ATOM   2858 H HG3  . ARG B 2 87  ? -5.166  35.138 -2.880  1.00 30.88 ? 87  ARG H HG3  1 
ATOM   2859 H HD2  . ARG B 2 87  ? -6.561  34.268 -4.587  1.00 33.75 ? 87  ARG H HD2  1 
ATOM   2860 H HD3  . ARG B 2 87  ? -5.947  33.134 -3.659  1.00 33.75 ? 87  ARG H HD3  1 
ATOM   2861 H HE   . ARG B 2 87  ? -8.010  32.853 -2.756  1.00 38.09 ? 87  ARG H HE   1 
ATOM   2862 H HH11 . ARG B 2 87  ? -8.137  35.151 -5.110  1.00 35.97 ? 87  ARG H HH11 1 
ATOM   2863 H HH12 . ARG B 2 87  ? -9.560  34.922 -5.486  1.00 35.97 ? 87  ARG H HH12 1 
ATOM   2864 H HH21 . ARG B 2 87  ? -10.186 32.587 -3.261  1.00 39.88 ? 87  ARG H HH21 1 
ATOM   2865 H HH22 . ARG B 2 87  ? -10.801 33.373 -4.367  1.00 39.88 ? 87  ARG H HH22 1 
ATOM   2866 N N    . ALA B 2 88  ? -7.030  34.765 1.667   1.00 20.66 ? 88  ALA H N    1 
ATOM   2867 C CA   . ALA B 2 88  ? -7.182  34.258 3.025   1.00 24.37 ? 88  ALA H CA   1 
ATOM   2868 C C    . ALA B 2 88  ? -6.385  32.980 3.201   1.00 22.09 ? 88  ALA H C    1 
ATOM   2869 O O    . ALA B 2 88  ? -5.690  32.808 4.211   1.00 21.71 ? 88  ALA H O    1 
ATOM   2870 C CB   . ALA B 2 88  ? -8.655  34.017 3.335   1.00 30.49 ? 88  ALA H CB   1 
ATOM   2871 H H    . ALA B 2 88  ? -7.772  34.897 1.252   1.00 24.85 ? 88  ALA H H    1 
ATOM   2872 H HA   . ALA B 2 88  ? -6.854  34.919 3.654   1.00 29.31 ? 88  ALA H HA   1 
ATOM   2873 H HB1  . ALA B 2 88  ? -8.737  33.689 4.244   1.00 36.65 ? 88  ALA H HB1  1 
ATOM   2874 H HB2  . ALA B 2 88  ? -9.139  34.852 3.240   1.00 36.65 ? 88  ALA H HB2  1 
ATOM   2875 H HB3  . ALA B 2 88  ? -9.005  33.359 2.713   1.00 36.65 ? 88  ALA H HB3  1 
ATOM   2876 N N    . GLU B 2 89  ? -6.450  32.091 2.203   1.00 21.31 ? 89  GLU H N    1 
ATOM   2877 C CA   . GLU B 2 89  ? -5.806  30.798 2.278   1.00 21.69 ? 89  GLU H CA   1 
ATOM   2878 C C    . GLU B 2 89  ? -4.292  30.904 2.280   1.00 21.89 ? 89  GLU H C    1 
ATOM   2879 O O    . GLU B 2 89  ? -3.639  29.884 2.523   1.00 23.76 ? 89  GLU H O    1 
ATOM   2880 C CB   . GLU B 2 89  ? -6.228  29.888 1.122   1.00 23.77 ? 89  GLU H CB   1 
ATOM   2881 C CG   . GLU B 2 89  ? -5.999  30.434 -0.276  1.00 34.39 ? 89  GLU H CG   1 
ATOM   2882 C CD   . GLU B 2 89  ? -7.198  31.166 -0.862  1.00 40.25 ? 89  GLU H CD   1 
ATOM   2883 O OE1  . GLU B 2 89  ? -8.040  31.710 -0.076  1.00 32.70 ? 89  GLU H OE1  1 
ATOM   2884 O OE2  . GLU B 2 89  ? -7.302  31.135 -2.115  1.00 32.53 ? 89  GLU H OE2  1 
ATOM   2885 H H    . GLU B 2 89  ? -6.871  32.224 1.464   1.00 25.63 ? 89  GLU H H    1 
ATOM   2886 H HA   . GLU B 2 89  ? -6.100  30.379 3.102   1.00 26.08 ? 89  GLU H HA   1 
ATOM   2887 H HB2  . GLU B 2 89  ? -5.728  29.060 1.191   1.00 28.58 ? 89  GLU H HB2  1 
ATOM   2888 H HB3  . GLU B 2 89  ? -7.178  29.711 1.208   1.00 28.58 ? 89  GLU H HB3  1 
ATOM   2889 H HG2  . GLU B 2 89  ? -5.257  31.058 -0.249  1.00 41.33 ? 89  GLU H HG2  1 
ATOM   2890 H HG3  . GLU B 2 89  ? -5.788  29.694 -0.868  1.00 41.33 ? 89  GLU H HG3  1 
ATOM   2891 N N    . ASP B 2 90  ? -3.721  32.081 2.005   1.00 15.66 ? 90  ASP H N    1 
ATOM   2892 C CA   . ASP B 2 90  ? -2.273  32.225 2.081   1.00 14.16 ? 90  ASP H CA   1 
ATOM   2893 C C    . ASP B 2 90  ? -1.781  32.507 3.490   1.00 14.37 ? 90  ASP H C    1 
ATOM   2894 O O    . ASP B 2 90  ? -0.574  32.650 3.673   1.00 16.68 ? 90  ASP H O    1 
ATOM   2895 C CB   . ASP B 2 90  ? -1.742  33.341 1.175   1.00 16.63 ? 90  ASP H CB   1 
ATOM   2896 C CG   . ASP B 2 90  ? -2.087  33.129 -0.292  1.00 20.69 ? 90  ASP H CG   1 
ATOM   2897 O OD1  . ASP B 2 90  ? -1.741  32.077 -0.856  1.00 21.21 ? 90  ASP H OD1  1 
ATOM   2898 O OD2  . ASP B 2 90  ? -2.547  34.109 -0.943  1.00 18.33 ? 90  ASP H OD2  1 
ATOM   2899 H H    . ASP B 2 90  ? -4.145  32.793 1.777   1.00 18.85 ? 90  ASP H H    1 
ATOM   2900 H HA   . ASP B 2 90  ? -1.904  31.387 1.758   1.00 17.06 ? 90  ASP H HA   1 
ATOM   2901 H HB2  . ASP B 2 90  ? -2.129  34.185 1.455   1.00 20.02 ? 90  ASP H HB2  1 
ATOM   2902 H HB3  . ASP B 2 90  ? -0.776  33.377 1.253   1.00 20.02 ? 90  ASP H HB3  1 
ATOM   2903 N N    . THR B 2 91  ? -2.677  32.571 4.472   1.00 15.87 ? 91  THR H N    1 
ATOM   2904 C CA   . THR B 2 91  ? -2.287  32.747 5.856   1.00 18.03 ? 91  THR H CA   1 
ATOM   2905 C C    . THR B 2 91  ? -1.498  31.537 6.304   1.00 16.80 ? 91  THR H C    1 
ATOM   2906 O O    . THR B 2 91  ? -1.964  30.405 6.174   1.00 16.51 ? 91  THR H O    1 
ATOM   2907 C CB   . THR B 2 91  ? -3.529  32.940 6.723   1.00 18.87 ? 91  THR H CB   1 
ATOM   2908 O OG1  . THR B 2 91  ? -4.160  34.172 6.355   1.00 19.66 ? 91  THR H OG1  1 
ATOM   2909 C CG2  . THR B 2 91  ? -3.221  32.965 8.184   1.00 18.52 ? 91  THR H CG2  1 
ATOM   2910 H H    . THR B 2 91  ? -3.527  32.513 4.357   1.00 19.11 ? 91  THR H H    1 
ATOM   2911 H HA   . THR B 2 91  ? -1.732  33.537 5.958   1.00 21.70 ? 91  THR H HA   1 
ATOM   2912 H HB   . THR B 2 91  ? -4.123  32.187 6.578   1.00 22.70 ? 91  THR H HB   1 
ATOM   2913 H HG1  . THR B 2 91  ? -4.633  34.060 5.670   1.00 23.66 ? 91  THR H HG1  1 
ATOM   2914 H HG21 . THR B 2 91  ? -3.935  33.412 8.666   1.00 22.28 ? 91  THR H HG21 1 
ATOM   2915 H HG22 . THR B 2 91  ? -3.133  32.060 8.520   1.00 22.28 ? 91  THR H HG22 1 
ATOM   2916 H HG23 . THR B 2 91  ? -2.391  33.442 8.340   1.00 22.28 ? 91  THR H HG23 1 
ATOM   2917 N N    . ALA B 2 92  ? -0.314  31.783 6.846   1.00 13.73 ? 92  ALA H N    1 
ATOM   2918 C CA   . ALA B 2 92  ? 0.571   30.685 7.160   1.00 16.91 ? 92  ALA H CA   1 
ATOM   2919 C C    . ALA B 2 92  ? 1.833   31.223 7.794   1.00 16.38 ? 92  ALA H C    1 
ATOM   2920 O O    . ALA B 2 92  ? 2.198   32.394 7.626   1.00 15.24 ? 92  ALA H O    1 
ATOM   2921 C CB   . ALA B 2 92  ? 0.933   29.900 5.892   1.00 12.41 ? 92  ALA H CB   1 
ATOM   2922 H H    . ALA B 2 92  ? -0.011  32.565 7.036   1.00 16.53 ? 92  ALA H H    1 
ATOM   2923 H HA   . ALA B 2 92  ? 0.139   30.102 7.803   1.00 20.35 ? 92  ALA H HA   1 
ATOM   2924 H HB1  . ALA B 2 92  ? 1.609   29.240 6.112   1.00 14.95 ? 92  ALA H HB1  1 
ATOM   2925 H HB2  . ALA B 2 92  ? 0.137   29.459 5.556   1.00 14.95 ? 92  ALA H HB2  1 
ATOM   2926 H HB3  . ALA B 2 92  ? 1.276   30.516 5.226   1.00 14.95 ? 92  ALA H HB3  1 
ATOM   2927 N N    . ILE B 2 93  ? 2.559   30.320 8.413   1.00 13.27 ? 93  ILE H N    1 
ATOM   2928 C CA   . ILE B 2 93  ? 3.955   30.563 8.750   1.00 13.30 ? 93  ILE H CA   1 
ATOM   2929 C C    . ILE B 2 93  ? 4.799   30.310 7.514   1.00 14.32 ? 93  ILE H C    1 
ATOM   2930 O O    . ILE B 2 93  ? 4.657   29.259 6.879   1.00 14.06 ? 93  ILE H O    1 
ATOM   2931 C CB   . ILE B 2 93  ? 4.386   29.665 9.918   1.00 17.18 ? 93  ILE H CB   1 
ATOM   2932 C CG1  . ILE B 2 93  ? 3.519   29.962 11.148  1.00 23.86 ? 93  ILE H CG1  1 
ATOM   2933 C CG2  . ILE B 2 93  ? 5.849   29.875 10.206  1.00 16.77 ? 93  ILE H CG2  1 
ATOM   2934 C CD1  . ILE B 2 93  ? 4.103   29.465 12.453  1.00 27.85 ? 93  ILE H CD1  1 
ATOM   2935 H H    . ILE B 2 93  ? 2.270   29.547 8.654   1.00 15.98 ? 93  ILE H H    1 
ATOM   2936 H HA   . ILE B 2 93  ? 4.073   31.487 9.019   1.00 16.02 ? 93  ILE H HA   1 
ATOM   2937 H HB   . ILE B 2 93  ? 4.256   28.733 9.681   1.00 20.68 ? 93  ILE H HB   1 
ATOM   2938 H HG12 . ILE B 2 93  ? 3.407   30.923 11.224  1.00 28.70 ? 93  ILE H HG12 1 
ATOM   2939 H HG13 . ILE B 2 93  ? 2.656   29.535 11.031  1.00 28.70 ? 93  ILE H HG13 1 
ATOM   2940 H HG21 . ILE B 2 93  ? 6.106   29.320 10.958  1.00 20.19 ? 93  ILE H HG21 1 
ATOM   2941 H HG22 . ILE B 2 93  ? 6.364   29.628 9.421   1.00 20.19 ? 93  ILE H HG22 1 
ATOM   2942 H HG23 . ILE B 2 93  ? 5.998   30.810 10.418  1.00 20.19 ? 93  ILE H HG23 1 
ATOM   2943 H HD11 . ILE B 2 93  ? 3.481   29.659 13.171  1.00 33.48 ? 93  ILE H HD11 1 
ATOM   2944 H HD12 . ILE B 2 93  ? 4.247   28.508 12.389  1.00 33.48 ? 93  ILE H HD12 1 
ATOM   2945 H HD13 . ILE B 2 93  ? 4.946   29.916 12.614  1.00 33.48 ? 93  ILE H HD13 1 
ATOM   2946 N N    . TYR B 2 94  ? 5.649   31.267 7.148   1.00 13.22 ? 94  TYR H N    1 
ATOM   2947 C CA   . TYR B 2 94  ? 6.504   31.167 5.967   1.00 14.36 ? 94  TYR H CA   1 
ATOM   2948 C C    . TYR B 2 94  ? 7.911   30.936 6.463   1.00 14.23 ? 94  TYR H C    1 
ATOM   2949 O O    . TYR B 2 94  ? 8.444   31.771 7.205   1.00 14.68 ? 94  TYR H O    1 
ATOM   2950 C CB   . TYR B 2 94  ? 6.439   32.411 5.071   1.00 14.08 ? 94  TYR H CB   1 
ATOM   2951 C CG   . TYR B 2 94  ? 5.161   32.417 4.272   1.00 12.92 ? 94  TYR H CG   1 
ATOM   2952 C CD1  . TYR B 2 94  ? 3.937   32.707 4.866   1.00 13.51 ? 94  TYR H CD1  1 
ATOM   2953 C CD2  . TYR B 2 94  ? 5.152   32.079 2.911   1.00 14.24 ? 94  TYR H CD2  1 
ATOM   2954 C CE1  . TYR B 2 94  ? 2.757   32.673 4.139   1.00 14.08 ? 94  TYR H CE1  1 
ATOM   2955 C CE2  . TYR B 2 94  ? 3.962   32.056 2.192   1.00 14.00 ? 94  TYR H CE2  1 
ATOM   2956 C CZ   . TYR B 2 94  ? 2.767   32.331 2.827   1.00 15.07 ? 94  TYR H CZ   1 
ATOM   2957 O OH   . TYR B 2 94  ? 1.588   32.298 2.143   1.00 14.96 ? 94  TYR H OH   1 
ATOM   2958 H H    . TYR B 2 94  ? 5.750   32.003 7.580   1.00 15.92 ? 94  TYR H H    1 
ATOM   2959 H HA   . TYR B 2 94  ? 6.212   30.422 5.418   1.00 17.30 ? 94  TYR H HA   1 
ATOM   2960 H HB2  . TYR B 2 94  ? 6.464   33.209 5.621   1.00 16.96 ? 94  TYR H HB2  1 
ATOM   2961 H HB3  . TYR B 2 94  ? 7.189   32.407 4.456   1.00 16.96 ? 94  TYR H HB3  1 
ATOM   2962 H HD1  . TYR B 2 94  ? 3.910   32.928 5.769   1.00 16.27 ? 94  TYR H HD1  1 
ATOM   2963 H HD2  . TYR B 2 94  ? 5.952   31.869 2.485   1.00 17.15 ? 94  TYR H HD2  1 
ATOM   2964 H HE1  . TYR B 2 94  ? 1.953   32.887 4.554   1.00 16.96 ? 94  TYR H HE1  1 
ATOM   2965 H HE2  . TYR B 2 94  ? 3.971   31.856 1.284   1.00 16.87 ? 94  TYR H HE2  1 
ATOM   2966 H HH   . TYR B 2 94  ? 0.943   32.327 2.681   1.00 18.01 ? 94  TYR H HH   1 
ATOM   2967 N N    . TYR B 2 95  ? 8.489   29.781 6.093   1.00 13.49 ? 95  TYR H N    1 
ATOM   2968 C CA   . TYR B 2 95  ? 9.832   29.375 6.438   1.00 12.69 ? 95  TYR H CA   1 
ATOM   2969 C C    . TYR B 2 95  ? 10.768  29.506 5.234   1.00 15.45 ? 95  TYR H C    1 
ATOM   2970 O O    . TYR B 2 95  ? 10.404  29.132 4.105   1.00 12.68 ? 95  TYR H O    1 
ATOM   2971 C CB   . TYR B 2 95  ? 9.885   27.894 6.852   1.00 13.31 ? 95  TYR H CB   1 
ATOM   2972 C CG   . TYR B 2 95  ? 9.092   27.505 8.045   1.00 15.12 ? 95  TYR H CG   1 
ATOM   2973 C CD1  . TYR B 2 95  ? 9.533   27.763 9.324   1.00 16.78 ? 95  TYR H CD1  1 
ATOM   2974 C CD2  . TYR B 2 95  ? 7.868   26.880 7.871   1.00 16.44 ? 95  TYR H CD2  1 
ATOM   2975 C CE1  . TYR B 2 95  ? 8.764   27.422 10.416  1.00 16.14 ? 95  TYR H CE1  1 
ATOM   2976 C CE2  . TYR B 2 95  ? 7.117   26.503 8.930   1.00 17.16 ? 95  TYR H CE2  1 
ATOM   2977 C CZ   . TYR B 2 95  ? 7.569   26.789 10.213  1.00 19.25 ? 95  TYR H CZ   1 
ATOM   2978 O OH   . TYR B 2 95  ? 6.802   26.438 11.295  1.00 26.45 ? 95  TYR H OH   1 
ATOM   2979 H H    . TYR B 2 95  ? 8.087   29.191 5.613   1.00 16.25 ? 95  TYR H H    1 
ATOM   2980 H HA   . TYR B 2 95  ? 10.128  29.948 7.162   1.00 15.28 ? 95  TYR H HA   1 
ATOM   2981 H HB2  . TYR B 2 95  ? 9.557   27.363 6.109   1.00 16.03 ? 95  TYR H HB2  1 
ATOM   2982 H HB3  . TYR B 2 95  ? 10.809  27.667 7.039   1.00 16.03 ? 95  TYR H HB3  1 
ATOM   2983 H HD1  . TYR B 2 95  ? 10.359  28.172 9.451   1.00 20.19 ? 95  TYR H HD1  1 
ATOM   2984 H HD2  . TYR B 2 95  ? 7.557   26.717 7.010   1.00 19.79 ? 95  TYR H HD2  1 
ATOM   2985 H HE1  . TYR B 2 95  ? 9.054   27.618 11.278  1.00 19.43 ? 95  TYR H HE1  1 
ATOM   2986 H HE2  . TYR B 2 95  ? 6.309   26.060 8.802   1.00 20.66 ? 95  TYR H HE2  1 
ATOM   2987 H HH   . TYR B 2 95  ? 6.172   25.939 11.051  1.00 31.80 ? 95  TYR H HH   1 
ATOM   2988 N N    . CYS B 2 96  ? 11.997  29.939 5.490   1.00 13.32 ? 96  CYS H N    1 
ATOM   2989 C CA   . CYS B 2 96  ? 13.058  29.900 4.496   1.00 15.73 ? 96  CYS H CA   1 
ATOM   2990 C C    . CYS B 2 96  ? 13.886  28.632 4.766   1.00 15.25 ? 96  CYS H C    1 
ATOM   2991 O O    . CYS B 2 96  ? 14.121  28.254 5.922   1.00 13.96 ? 96  CYS H O    1 
ATOM   2992 C CB   . CYS B 2 96  ? 13.889  31.197 4.584   1.00 18.87 ? 96  CYS H CB   1 
ATOM   2993 S SG   . CYS B 2 96  ? 15.494  31.310 3.940   1.00 26.89 ? 96  CYS H SG   1 
ATOM   2994 H H    . CYS B 2 96  ? 12.243  30.266 6.247   1.00 16.05 ? 96  CYS H H    1 
ATOM   2995 H HA   . CYS B 2 96  ? 12.732  29.849 3.584   1.00 18.93 ? 96  CYS H HA   1 
ATOM   2996 H HB2  . CYS B 2 96  ? 13.379  31.886 4.132   1.00 22.70 ? 96  CYS H HB2  1 
ATOM   2997 H HB3  . CYS B 2 96  ? 13.972  31.411 5.527   1.00 22.70 ? 96  CYS H HB3  1 
ATOM   2998 N N    . ALA B 2 97  ? 14.225  27.903 3.707   1.00 14.47 ? 97  ALA H N    1 
ATOM   2999 C CA   . ALA B 2 97  ? 14.945  26.643 3.841   1.00 11.40 ? 97  ALA H CA   1 
ATOM   3000 C C    . ALA B 2 97  ? 16.063  26.519 2.825   1.00 9.84  ? 97  ALA H C    1 
ATOM   3001 O O    . ALA B 2 97  ? 15.917  26.896 1.655   1.00 10.44 ? 97  ALA H O    1 
ATOM   3002 C CB   . ALA B 2 97  ? 13.997  25.442 3.711   1.00 14.24 ? 97  ALA H CB   1 
ATOM   3003 H H    . ALA B 2 97  ? 14.048  28.120 2.893   1.00 17.43 ? 97  ALA H H    1 
ATOM   3004 H HA   . ALA B 2 97  ? 15.362  26.632 4.717   1.00 13.74 ? 97  ALA H HA   1 
ATOM   3005 H HB1  . ALA B 2 97  ? 14.521  24.625 3.701   1.00 17.15 ? 97  ALA H HB1  1 
ATOM   3006 H HB2  . ALA B 2 97  ? 13.389  25.436 4.466   1.00 17.15 ? 97  ALA H HB2  1 
ATOM   3007 H HB3  . ALA B 2 97  ? 13.497  25.523 2.884   1.00 17.15 ? 97  ALA H HB3  1 
ATOM   3008 N N    . ARG B 2 98  ? 17.183  26.028 3.285   1.00 10.67 ? 98  ARG H N    1 
ATOM   3009 C CA   . ARG B 2 98  ? 18.288  25.725 2.400   1.00 11.62 ? 98  ARG H CA   1 
ATOM   3010 C C    . ARG B 2 98  ? 18.168  24.281 1.915   1.00 11.71 ? 98  ARG H C    1 
ATOM   3011 O O    . ARG B 2 98  ? 17.810  23.385 2.679   1.00 13.97 ? 98  ARG H O    1 
ATOM   3012 C CB   . ARG B 2 98  ? 19.605  25.983 3.127   1.00 13.92 ? 98  ARG H CB   1 
ATOM   3013 C CG   . ARG B 2 98  ? 20.812  25.591 2.375   1.00 14.96 ? 98  ARG H CG   1 
ATOM   3014 C CD   . ARG B 2 98  ? 22.056  25.795 3.230   1.00 15.87 ? 98  ARG H CD   1 
ATOM   3015 N NE   . ARG B 2 98  ? 22.595  24.505 3.575   1.00 15.59 ? 98  ARG H NE   1 
ATOM   3016 C CZ   . ARG B 2 98  ? 23.766  24.291 4.150   1.00 18.65 ? 98  ARG H CZ   1 
ATOM   3017 N NH1  . ARG B 2 98  ? 24.683  25.250 4.237   1.00 18.26 ? 98  ARG H NH1  1 
ATOM   3018 N NH2  . ARG B 2 98  ? 24.047  23.067 4.557   1.00 17.58 ? 98  ARG H NH2  1 
ATOM   3019 H H    . ARG B 2 98  ? 17.335  25.857 4.113   1.00 12.86 ? 98  ARG H H    1 
ATOM   3020 H HA   . ARG B 2 98  ? 18.279  26.291 1.612   1.00 14.00 ? 98  ARG H HA   1 
ATOM   3021 H HB2  . ARG B 2 98  ? 19.673  26.932 3.315   1.00 16.76 ? 98  ARG H HB2  1 
ATOM   3022 H HB3  . ARG B 2 98  ? 19.603  25.480 3.957   1.00 16.76 ? 98  ARG H HB3  1 
ATOM   3023 H HG2  . ARG B 2 98  ? 20.754  24.655 2.130   1.00 18.02 ? 98  ARG H HG2  1 
ATOM   3024 H HG3  . ARG B 2 98  ? 20.891  26.139 1.578   1.00 18.02 ? 98  ARG H HG3  1 
ATOM   3025 H HD2  . ARG B 2 98  ? 22.722  26.294 2.732   1.00 19.10 ? 98  ARG H HD2  1 
ATOM   3026 H HD3  . ARG B 2 98  ? 21.825  26.270 4.043   1.00 19.10 ? 98  ARG H HD3  1 
ATOM   3027 H HE   . ARG B 2 98  ? 22.115  23.816 3.392   1.00 18.77 ? 98  ARG H HE   1 
ATOM   3028 H HH11 . ARG B 2 98  ? 24.521  26.031 3.915   1.00 21.97 ? 98  ARG H HH11 1 
ATOM   3029 H HH12 . ARG B 2 98  ? 25.439  25.090 4.615   1.00 21.97 ? 98  ARG H HH12 1 
ATOM   3030 H HH21 . ARG B 2 98  ? 23.475  22.435 4.445   1.00 21.16 ? 98  ARG H HH21 1 
ATOM   3031 H HH22 . ARG B 2 98  ? 24.802  22.902 4.934   1.00 21.16 ? 98  ARG H HH22 1 
ATOM   3032 N N    . THR B 2 99  ? 18.569  24.057 0.665   1.00 11.73 ? 99  THR H N    1 
ATOM   3033 C CA   . THR B 2 99  ? 18.736  22.727 0.083   1.00 10.81 ? 99  THR H CA   1 
ATOM   3034 C C    . THR B 2 99  ? 20.190  22.278 0.282   1.00 13.60 ? 99  THR H C    1 
ATOM   3035 O O    . THR B 2 99  ? 21.148  22.894 -0.218  1.00 12.10 ? 99  THR H O    1 
ATOM   3036 C CB   . THR B 2 99  ? 18.412  22.700 -1.413  1.00 12.91 ? 99  THR H CB   1 
ATOM   3037 O OG1  . THR B 2 99  ? 17.190  23.379 -1.707  1.00 11.39 ? 99  THR H OG1  1 
ATOM   3038 C CG2  . THR B 2 99  ? 18.313  21.313 -1.923  1.00 14.41 ? 99  THR H CG2  1 
ATOM   3039 H H    . THR B 2 99  ? 18.758  24.687 0.111   1.00 14.14 ? 99  THR H H    1 
ATOM   3040 H HA   . THR B 2 99  ? 18.127  22.123 0.537   1.00 13.03 ? 99  THR H HA   1 
ATOM   3041 H HB   . THR B 2 99  ? 19.138  23.154 -1.868  1.00 15.56 ? 99  THR H HB   1 
ATOM   3042 H HG1  . THR B 2 99  ? 17.272  24.200 -1.547  1.00 13.72 ? 99  THR H HG1  1 
ATOM   3043 H HG21 . THR B 2 99  ? 18.096  21.321 -2.868  1.00 17.35 ? 99  THR H HG21 1 
ATOM   3044 H HG22 . THR B 2 99  ? 19.158  20.853 -1.798  1.00 17.35 ? 99  THR H HG22 1 
ATOM   3045 H HG23 . THR B 2 99  ? 17.620  20.832 -1.445  1.00 17.35 ? 99  THR H HG23 1 
ATOM   3046 N N    . GLY B 2 100 ? 20.376  21.201 1.000   1.00 13.35 ? 100 GLY H N    1 
ATOM   3047 C CA   . GLY B 2 100 ? 21.701  20.625 1.043   1.00 11.50 ? 100 GLY H CA   1 
ATOM   3048 C C    . GLY B 2 100 ? 22.188  20.192 -0.332  1.00 14.12 ? 100 GLY H C    1 
ATOM   3049 O O    . GLY B 2 100 ? 21.432  19.933 -1.267  1.00 11.83 ? 100 GLY H O    1 
ATOM   3050 H H    . GLY B 2 100 ? 19.775  20.793 1.460   1.00 16.09 ? 100 GLY H H    1 
ATOM   3051 H HA2  . GLY B 2 100 ? 22.324  21.278 1.397   1.00 13.86 ? 100 GLY H HA2  1 
ATOM   3052 H HA3  . GLY B 2 100 ? 21.694  19.847 1.623   1.00 13.86 ? 100 GLY H HA3  1 
ATOM   3053 N N    . TRP B 2 101 ? 23.494  20.038 -0.442  1.00 13.98 ? 101 TRP H N    1 
ATOM   3054 C CA   . TRP B 2 101 ? 24.057  19.679 -1.740  1.00 13.53 ? 101 TRP H CA   1 
ATOM   3055 C C    . TRP B 2 101 ? 23.584  18.310 -2.219  1.00 12.28 ? 101 TRP H C    1 
ATOM   3056 O O    . TRP B 2 101 ? 23.561  18.066 -3.423  1.00 14.37 ? 101 TRP H O    1 
ATOM   3057 C CB   . TRP B 2 101 ? 25.578  19.708 -1.677  1.00 14.38 ? 101 TRP H CB   1 
ATOM   3058 C CG   . TRP B 2 101 ? 26.137  21.087 -1.673  1.00 14.90 ? 101 TRP H CG   1 
ATOM   3059 C CD1  . TRP B 2 101 ? 25.499  22.230 -2.018  1.00 18.01 ? 101 TRP H CD1  1 
ATOM   3060 C CD2  . TRP B 2 101 ? 27.466  21.466 -1.284  1.00 16.22 ? 101 TRP H CD2  1 
ATOM   3061 N NE1  . TRP B 2 101 ? 26.350  23.314 -1.876  1.00 17.83 ? 101 TRP H NE1  1 
ATOM   3062 C CE2  . TRP B 2 101 ? 27.573  22.861 -1.448  1.00 18.33 ? 101 TRP H CE2  1 
ATOM   3063 C CE3  . TRP B 2 101 ? 28.585  20.751 -0.847  1.00 20.96 ? 101 TRP H CE3  1 
ATOM   3064 C CZ2  . TRP B 2 101 ? 28.745  23.561 -1.141  1.00 21.18 ? 101 TRP H CZ2  1 
ATOM   3065 C CZ3  . TRP B 2 101 ? 29.734  21.456 -0.539  1.00 23.42 ? 101 TRP H CZ3  1 
ATOM   3066 C CH2  . TRP B 2 101 ? 29.807  22.828 -0.707  1.00 19.19 ? 101 TRP H CH2  1 
ATOM   3067 H H    . TRP B 2 101 ? 24.064  20.132 0.195   1.00 16.83 ? 101 TRP H H    1 
ATOM   3068 H HA   . TRP B 2 101 ? 23.761  20.336 -2.389  1.00 16.29 ? 101 TRP H HA   1 
ATOM   3069 H HB2  . TRP B 2 101 ? 25.867  19.266 -0.863  1.00 17.31 ? 101 TRP H HB2  1 
ATOM   3070 H HB3  . TRP B 2 101 ? 25.933  19.244 -2.451  1.00 17.31 ? 101 TRP H HB3  1 
ATOM   3071 H HD1  . TRP B 2 101 ? 24.617  22.280 -2.309  1.00 21.68 ? 101 TRP H HD1  1 
ATOM   3072 H HE1  . TRP B 2 101 ? 26.145  24.135 -2.029  1.00 21.45 ? 101 TRP H HE1  1 
ATOM   3073 H HE3  . TRP B 2 101 ? 28.558  19.825 -0.765  1.00 25.22 ? 101 TRP H HE3  1 
ATOM   3074 H HZ2  . TRP B 2 101 ? 28.796  24.485 -1.229  1.00 25.48 ? 101 TRP H HZ2  1 
ATOM   3075 H HZ3  . TRP B 2 101 ? 30.475  20.998 -0.212  1.00 28.16 ? 101 TRP H HZ3  1 
ATOM   3076 H HH2  . TRP B 2 101 ? 30.607  23.263 -0.517  1.00 23.09 ? 101 TRP H HH2  1 
ATOM   3077 N N    . LEU B 2 102 ? 23.191  17.425 -1.306  1.00 13.21 ? 102 LEU H N    1 
ATOM   3078 C CA   . LEU B 2 102 ? 22.672  16.118 -1.663  1.00 14.21 ? 102 LEU H CA   1 
ATOM   3079 C C    . LEU B 2 102 ? 21.164  16.128 -1.897  1.00 10.49 ? 102 LEU H C    1 
ATOM   3080 O O    . LEU B 2 102 ? 20.614  15.084 -2.275  1.00 12.26 ? 102 LEU H O    1 
ATOM   3081 C CB   . LEU B 2 102 ? 23.028  15.091 -0.583  1.00 14.92 ? 102 LEU H CB   1 
ATOM   3082 C CG   . LEU B 2 102 ? 24.531  14.967 -0.338  1.00 18.35 ? 102 LEU H CG   1 
ATOM   3083 C CD1  . LEU B 2 102 ? 24.833  13.993 0.769   1.00 23.65 ? 102 LEU H CD1  1 
ATOM   3084 C CD2  . LEU B 2 102 ? 25.214  14.546 -1.625  1.00 20.05 ? 102 LEU H CD2  1 
ATOM   3085 H H    . LEU B 2 102 ? 23.217  17.566 -0.458  1.00 15.91 ? 102 LEU H H    1 
ATOM   3086 H HA   . LEU B 2 102 ? 23.096  15.829 -2.487  1.00 17.11 ? 102 LEU H HA   1 
ATOM   3087 H HB2  . LEU B 2 102 ? 22.610  15.357 0.251   1.00 17.96 ? 102 LEU H HB2  1 
ATOM   3088 H HB3  . LEU B 2 102 ? 22.697  14.221 -0.857  1.00 17.96 ? 102 LEU H HB3  1 
ATOM   3089 H HG   . LEU B 2 102 ? 24.881  15.827 -0.057  1.00 22.09 ? 102 LEU H HG   1 
ATOM   3090 H HD11 . LEU B 2 102 ? 25.724  14.168 1.109   1.00 28.44 ? 102 LEU H HD11 1 
ATOM   3091 H HD12 . LEU B 2 102 ? 24.180  14.106 1.477   1.00 28.44 ? 102 LEU H HD12 1 
ATOM   3092 H HD13 . LEU B 2 102 ? 24.785  13.090 0.416   1.00 28.44 ? 102 LEU H HD13 1 
ATOM   3093 H HD21 . LEU B 2 102 ? 26.134  14.306 -1.431  1.00 24.12 ? 102 LEU H HD21 1 
ATOM   3094 H HD22 . LEU B 2 102 ? 24.745  13.783 -1.997  1.00 24.12 ? 102 LEU H HD22 1 
ATOM   3095 H HD23 . LEU B 2 102 ? 25.191  15.286 -2.252  1.00 24.12 ? 102 LEU H HD23 1 
ATOM   3096 N N    . GLY B 2 103 ? 20.508  17.297 -1.743  1.00 10.82 ? 103 GLY H N    1 
ATOM   3097 C CA   . GLY B 2 103 ? 19.116  17.460 -2.094  1.00 11.07 ? 103 GLY H CA   1 
ATOM   3098 C C    . GLY B 2 103 ? 18.066  17.766 -1.016  1.00 12.85 ? 103 GLY H C    1 
ATOM   3099 O O    . GLY B 2 103 ? 17.032  18.361 -1.342  1.00 12.59 ? 103 GLY H O    1 
ATOM   3100 H H    . GLY B 2 103 ? 20.868  18.012 -1.430  1.00 13.05 ? 103 GLY H H    1 
ATOM   3101 H HA2  . GLY B 2 103 ? 19.064  18.187 -2.734  1.00 13.34 ? 103 GLY H HA2  1 
ATOM   3102 H HA3  . GLY B 2 103 ? 18.829  16.639 -2.524  1.00 13.34 ? 103 GLY H HA3  1 
ATOM   3103 N N    . PRO B 2 104 ? 18.230  17.346 0.252   1.00 11.52 ? 104 PRO H N    1 
ATOM   3104 C CA   . PRO B 2 104 ? 17.164  17.590 1.233   1.00 10.09 ? 104 PRO H CA   1 
ATOM   3105 C C    . PRO B 2 104 ? 17.240  19.032 1.746   1.00 11.28 ? 104 PRO H C    1 
ATOM   3106 O O    . PRO B 2 104 ? 18.185  19.767 1.454   1.00 12.49 ? 104 PRO H O    1 
ATOM   3107 C CB   . PRO B 2 104 ? 17.468  16.591 2.362   1.00 10.94 ? 104 PRO H CB   1 
ATOM   3108 C CG   . PRO B 2 104 ? 18.966  16.540 2.361   1.00 12.62 ? 104 PRO H CG   1 
ATOM   3109 C CD   . PRO B 2 104 ? 19.359  16.632 0.889   1.00 11.85 ? 104 PRO H CD   1 
ATOM   3110 H HA   . PRO B 2 104 ? 16.288  17.400 0.862   1.00 12.17 ? 104 PRO H HA   1 
ATOM   3111 H HB2  . PRO B 2 104 ? 17.124  16.920 3.208   1.00 13.19 ? 104 PRO H HB2  1 
ATOM   3112 H HB3  . PRO B 2 104 ? 17.082  15.724 2.162   1.00 13.19 ? 104 PRO H HB3  1 
ATOM   3113 H HG2  . PRO B 2 104 ? 19.323  17.289 2.864   1.00 15.20 ? 104 PRO H HG2  1 
ATOM   3114 H HG3  . PRO B 2 104 ? 19.269  15.704 2.750   1.00 15.20 ? 104 PRO H HG3  1 
ATOM   3115 H HD2  . PRO B 2 104 ? 20.182  17.135 0.787   1.00 14.29 ? 104 PRO H HD2  1 
ATOM   3116 H HD3  . PRO B 2 104 ? 19.463  15.746 0.507   1.00 14.29 ? 104 PRO H HD3  1 
ATOM   3117 N N    . PHE B 2 105 ? 16.204  19.439 2.478   1.00 11.81 ? 105 PHE H N    1 
ATOM   3118 C CA   . PHE B 2 105 ? 16.113  20.787 3.071   1.00 11.07 ? 105 PHE H CA   1 
ATOM   3119 C C    . PHE B 2 105 ? 16.751  20.716 4.450   1.00 13.09 ? 105 PHE H C    1 
ATOM   3120 O O    . PHE B 2 105 ? 16.098  20.342 5.441   1.00 12.08 ? 105 PHE H O    1 
ATOM   3121 C CB   . PHE B 2 105 ? 14.679  21.294 3.181   1.00 13.43 ? 105 PHE H CB   1 
ATOM   3122 C CG   . PHE B 2 105 ? 13.933  21.532 1.855   1.00 10.11 ? 105 PHE H CG   1 
ATOM   3123 C CD1  . PHE B 2 105 ? 14.481  21.220 0.637   1.00 12.20 ? 105 PHE H CD1  1 
ATOM   3124 C CD2  . PHE B 2 105 ? 12.667  22.119 1.872   1.00 11.23 ? 105 PHE H CD2  1 
ATOM   3125 C CE1  . PHE B 2 105 ? 13.780  21.404 -0.529  1.00 13.05 ? 105 PHE H CE1  1 
ATOM   3126 C CE2  . PHE B 2 105 ? 11.954  22.383 0.692   1.00 13.38 ? 105 PHE H CE2  1 
ATOM   3127 C CZ   . PHE B 2 105 ? 12.526  22.013 -0.524  1.00 11.96 ? 105 PHE H CZ   1 
ATOM   3128 H H    . PHE B 2 105 ? 15.522  18.946 2.653   1.00 14.24 ? 105 PHE H H    1 
ATOM   3129 H HA   . PHE B 2 105 ? 16.599  21.398 2.495   1.00 13.34 ? 105 PHE H HA   1 
ATOM   3130 H HB2  . PHE B 2 105 ? 14.166  20.641 3.683   1.00 16.17 ? 105 PHE H HB2  1 
ATOM   3131 H HB3  . PHE B 2 105 ? 14.693  22.140 3.655   1.00 16.17 ? 105 PHE H HB3  1 
ATOM   3132 H HD1  . PHE B 2 105 ? 15.345  20.876 0.600   1.00 14.70 ? 105 PHE H HD1  1 
ATOM   3133 H HD2  . PHE B 2 105 ? 12.284  22.342 2.690   1.00 13.53 ? 105 PHE H HD2  1 
ATOM   3134 H HE1  . PHE B 2 105 ? 14.146  21.117 -1.334  1.00 15.72 ? 105 PHE H HE1  1 
ATOM   3135 H HE2  . PHE B 2 105 ? 11.120  22.795 0.721   1.00 16.11 ? 105 PHE H HE2  1 
ATOM   3136 H HZ   . PHE B 2 105 ? 12.077  22.172 -1.323  1.00 14.42 ? 105 PHE H HZ   1 
ATOM   3137 N N    . ASP B 2 106 ? 18.061  21.019 4.507   1.00 13.07 ? 106 ASP H N    1 
ATOM   3138 C CA   . ASP B 2 106 ? 18.830  20.619 5.678   1.00 13.79 ? 106 ASP H CA   1 
ATOM   3139 C C    . ASP B 2 106 ? 18.838  21.660 6.782   1.00 15.15 ? 106 ASP H C    1 
ATOM   3140 O O    . ASP B 2 106 ? 19.080  21.294 7.942   1.00 14.29 ? 106 ASP H O    1 
ATOM   3141 C CB   . ASP B 2 106 ? 20.259  20.186 5.302   1.00 14.56 ? 106 ASP H CB   1 
ATOM   3142 C CG   . ASP B 2 106 ? 21.094  21.250 4.570   1.00 17.41 ? 106 ASP H CG   1 
ATOM   3143 O OD1  . ASP B 2 106 ? 20.606  22.355 4.274   1.00 15.01 ? 106 ASP H OD1  1 
ATOM   3144 O OD2  . ASP B 2 106 ? 22.279  20.916 4.265   1.00 15.07 ? 106 ASP H OD2  1 
ATOM   3145 H H    . ASP B 2 106 ? 18.501  21.439 3.900   1.00 15.74 ? 106 ASP H H    1 
ATOM   3146 H HA   . ASP B 2 106 ? 18.415  19.825 6.052   1.00 16.60 ? 106 ASP H HA   1 
ATOM   3147 H HB2  . ASP B 2 106 ? 20.733  19.955 6.116   1.00 17.54 ? 106 ASP H HB2  1 
ATOM   3148 H HB3  . ASP B 2 106 ? 20.202  19.412 4.721   1.00 17.54 ? 106 ASP H HB3  1 
ATOM   3149 N N    . TYR B 2 107 ? 18.519  22.919 6.477   1.00 13.99 ? 107 TYR H N    1 
ATOM   3150 C CA   . TYR B 2 107 ? 18.341  23.949 7.502   1.00 16.11 ? 107 TYR H CA   1 
ATOM   3151 C C    . TYR B 2 107 ? 17.123  24.795 7.171   1.00 13.77 ? 107 TYR H C    1 
ATOM   3152 O O    . TYR B 2 107 ? 16.871  25.115 6.006   1.00 15.27 ? 107 TYR H O    1 
ATOM   3153 C CB   . TYR B 2 107 ? 19.571  24.864 7.645   1.00 16.97 ? 107 TYR H CB   1 
ATOM   3154 C CG   . TYR B 2 107 ? 20.803  24.167 8.132   1.00 17.62 ? 107 TYR H CG   1 
ATOM   3155 C CD1  . TYR B 2 107 ? 21.622  23.433 7.289   1.00 19.17 ? 107 TYR H CD1  1 
ATOM   3156 C CD2  . TYR B 2 107 ? 21.093  24.180 9.479   1.00 21.75 ? 107 TYR H CD2  1 
ATOM   3157 C CE1  . TYR B 2 107 ? 22.768  22.776 7.786   1.00 18.65 ? 107 TYR H CE1  1 
ATOM   3158 C CE2  . TYR B 2 107 ? 22.193  23.547 9.987   1.00 25.13 ? 107 TYR H CE2  1 
ATOM   3159 C CZ   . TYR B 2 107 ? 23.024  22.839 9.156   1.00 27.53 ? 107 TYR H CZ   1 
ATOM   3160 O OH   . TYR B 2 107 ? 24.105  22.200 9.694   1.00 29.73 ? 107 TYR H OH   1 
ATOM   3161 H H    . TYR B 2 107 ? 18.398  23.203 5.674   1.00 16.85 ? 107 TYR H H    1 
ATOM   3162 H HA   . TYR B 2 107 ? 18.200  23.507 8.354   1.00 19.39 ? 107 TYR H HA   1 
ATOM   3163 H HB2  . TYR B 2 107 ? 19.774  25.249 6.778   1.00 20.42 ? 107 TYR H HB2  1 
ATOM   3164 H HB3  . TYR B 2 107 ? 19.361  25.568 8.279   1.00 20.42 ? 107 TYR H HB3  1 
ATOM   3165 H HD1  . TYR B 2 107 ? 21.413  23.373 6.385   1.00 23.07 ? 107 TYR H HD1  1 
ATOM   3166 H HD2  . TYR B 2 107 ? 20.524  24.633 10.059  1.00 26.17 ? 107 TYR H HD2  1 
ATOM   3167 H HE1  . TYR B 2 107 ? 23.337  22.312 7.215   1.00 22.44 ? 107 TYR H HE1  1 
ATOM   3168 H HE2  . TYR B 2 107 ? 22.378  23.595 10.897  1.00 30.22 ? 107 TYR H HE2  1 
ATOM   3169 H HH   . TYR B 2 107 ? 24.290  22.531 10.444  1.00 35.74 ? 107 TYR H HH   1 
ATOM   3170 N N    . TRP B 2 108 ? 16.416  25.204 8.227   1.00 14.23 ? 108 TRP H N    1 
ATOM   3171 C CA   . TRP B 2 108 ? 15.175  25.965 8.171   1.00 13.97 ? 108 TRP H CA   1 
ATOM   3172 C C    . TRP B 2 108 ? 15.246  27.131 9.152   1.00 19.79 ? 108 TRP H C    1 
ATOM   3173 O O    . TRP B 2 108 ? 15.782  26.978 10.252  1.00 18.49 ? 108 TRP H O    1 
ATOM   3174 C CB   . TRP B 2 108 ? 13.963  25.097 8.575   1.00 15.38 ? 108 TRP H CB   1 
ATOM   3175 C CG   . TRP B 2 108 ? 13.691  23.904 7.715   1.00 14.04 ? 108 TRP H CG   1 
ATOM   3176 C CD1  . TRP B 2 108 ? 14.522  22.837 7.518   1.00 15.05 ? 108 TRP H CD1  1 
ATOM   3177 C CD2  . TRP B 2 108 ? 12.507  23.636 6.967   1.00 12.96 ? 108 TRP H CD2  1 
ATOM   3178 N NE1  . TRP B 2 108 ? 13.917  21.900 6.722   1.00 13.84 ? 108 TRP H NE1  1 
ATOM   3179 C CE2  . TRP B 2 108 ? 12.683  22.370 6.351   1.00 14.04 ? 108 TRP H CE2  1 
ATOM   3180 C CE3  . TRP B 2 108 ? 11.293  24.309 6.791   1.00 13.51 ? 108 TRP H CE3  1 
ATOM   3181 C CZ2  . TRP B 2 108 ? 11.706  21.811 5.543   1.00 13.58 ? 108 TRP H CZ2  1 
ATOM   3182 C CZ3  . TRP B 2 108 ? 10.333  23.762 5.985   1.00 13.97 ? 108 TRP H CZ3  1 
ATOM   3183 C CH2  . TRP B 2 108 ? 10.531  22.521 5.384   1.00 13.80 ? 108 TRP H CH2  1 
ATOM   3184 H H    . TRP B 2 108 ? 16.653  25.041 9.037   1.00 17.14 ? 108 TRP H H    1 
ATOM   3185 H HA   . TRP B 2 108 ? 15.057  26.297 7.267   1.00 16.83 ? 108 TRP H HA   1 
ATOM   3186 H HB2  . TRP B 2 108 ? 14.111  24.772 9.476   1.00 18.52 ? 108 TRP H HB2  1 
ATOM   3187 H HB3  . TRP B 2 108 ? 13.169  25.655 8.549   1.00 18.52 ? 108 TRP H HB3  1 
ATOM   3188 H HD1  . TRP B 2 108 ? 15.377  22.759 7.874   1.00 18.12 ? 108 TRP H HD1  1 
ATOM   3189 H HE1  . TRP B 2 108 ? 14.255  21.143 6.493   1.00 16.66 ? 108 TRP H HE1  1 
ATOM   3190 H HE3  . TRP B 2 108 ? 11.140  25.121 7.218   1.00 16.28 ? 108 TRP H HE3  1 
ATOM   3191 H HZ2  . TRP B 2 108 ? 11.836  20.990 5.125   1.00 16.36 ? 108 TRP H HZ2  1 
ATOM   3192 H HZ3  . TRP B 2 108 ? 9.540   24.224 5.835   1.00 16.83 ? 108 TRP H HZ3  1 
ATOM   3193 H HH2  . TRP B 2 108 ? 9.853   22.159 4.861   1.00 16.62 ? 108 TRP H HH2  1 
ATOM   3194 N N    . GLY B 2 109 ? 14.670  28.275 8.792   1.00 14.94 ? 109 GLY H N    1 
ATOM   3195 C CA   . GLY B 2 109 ? 14.542  29.379 9.733   1.00 16.53 ? 109 GLY H CA   1 
ATOM   3196 C C    . GLY B 2 109 ? 13.415  29.088 10.713  1.00 17.49 ? 109 GLY H C    1 
ATOM   3197 O O    . GLY B 2 109 ? 12.748  28.073 10.629  1.00 19.51 ? 109 GLY H O    1 
ATOM   3198 H H    . GLY B 2 109 ? 14.348  28.434 8.011   1.00 17.99 ? 109 GLY H H    1 
ATOM   3199 H HA2  . GLY B 2 109 ? 15.370  29.493 10.225  1.00 19.90 ? 109 GLY H HA2  1 
ATOM   3200 H HA3  . GLY B 2 109 ? 14.344  30.200 9.255   1.00 19.90 ? 109 GLY H HA3  1 
ATOM   3201 N N    . GLN B 2 110 ? 13.183  30.002 11.651  1.00 15.74 ? 110 GLN H N    1 
ATOM   3202 C CA   . GLN B 2 110 ? 12.100  29.850 12.611  1.00 19.48 ? 110 GLN H CA   1 
ATOM   3203 C C    . GLN B 2 110 ? 10.765  30.265 12.008  1.00 18.18 ? 110 GLN H C    1 
ATOM   3204 O O    . GLN B 2 110 ? 9.712   30.022 12.618  1.00 19.34 ? 110 GLN H O    1 
ATOM   3205 C CB   . GLN B 2 110 ? 12.376  30.676 13.889  1.00 25.58 ? 110 GLN H CB   1 
ATOM   3206 H H    . GLN B 2 110 ? 13.642  30.722 11.751  1.00 18.95 ? 110 GLN H H    1 
ATOM   3207 H HA   . GLN B 2 110 ? 12.046  28.922 12.888  1.00 23.44 ? 110 GLN H HA   1 
ATOM   3208 N N    . GLY B 2 111 ? 10.764  31.009 10.898  1.00 17.34 ? 111 GLY H N    1 
ATOM   3209 C CA   . GLY B 2 111 ? 9.525   31.328 10.219  1.00 15.19 ? 111 GLY H CA   1 
ATOM   3210 C C    . GLY B 2 111 ? 9.000   32.699 10.590  1.00 19.25 ? 111 GLY H C    1 
ATOM   3211 O O    . GLY B 2 111 ? 9.373   33.287 11.611  1.00 18.10 ? 111 GLY H O    1 
ATOM   3212 H H    . GLY B 2 111 ? 11.468  31.335 10.528  1.00 20.87 ? 111 GLY H H    1 
ATOM   3213 H HA2  . GLY B 2 111 ? 9.670   31.306 9.260   1.00 18.29 ? 111 GLY H HA2  1 
ATOM   3214 H HA3  . GLY B 2 111 ? 8.852   30.670 10.452  1.00 18.29 ? 111 GLY H HA3  1 
ATOM   3215 N N    . THR B 2 112 ? 8.142   33.221 9.721   1.00 15.68 ? 112 THR H N    1 
ATOM   3216 C CA   . THR B 2 112 ? 7.488   34.496 9.966   1.00 17.35 ? 112 THR H CA   1 
ATOM   3217 C C    . THR B 2 112 ? 6.017   34.345 9.592   1.00 19.80 ? 112 THR H C    1 
ATOM   3218 O O    . THR B 2 112 ? 5.657   33.767 8.554   1.00 14.56 ? 112 THR H O    1 
ATOM   3219 C CB   . THR B 2 112 ? 8.179   35.606 9.154   1.00 17.41 ? 112 THR H CB   1 
ATOM   3220 O OG1  . THR B 2 112 ? 7.614   36.881 9.492   1.00 19.71 ? 112 THR H OG1  1 
ATOM   3221 C CG2  . THR B 2 112 ? 7.979   35.404 7.635   1.00 17.30 ? 112 THR H CG2  1 
ATOM   3222 H H    . THR B 2 112 ? 7.921   32.850 8.977   1.00 18.88 ? 112 THR H H    1 
ATOM   3223 H HA   . THR B 2 112 ? 7.529   34.749 10.902  1.00 20.89 ? 112 THR H HA   1 
ATOM   3224 H HB   . THR B 2 112 ? 9.127   35.580 9.357   1.00 20.95 ? 112 THR H HB   1 
ATOM   3225 H HG1  . THR B 2 112 ? 8.211   37.472 9.479   1.00 23.71 ? 112 THR H HG1  1 
ATOM   3226 H HG21 . THR B 2 112 ? 8.473   36.079 7.143   1.00 20.83 ? 112 THR H HG21 1 
ATOM   3227 H HG22 . THR B 2 112 ? 8.299   34.527 7.372   1.00 20.83 ? 112 THR H HG22 1 
ATOM   3228 H HG23 . THR B 2 112 ? 7.038   35.476 7.412   1.00 20.83 ? 112 THR H HG23 1 
ATOM   3229 N N    . LEU B 2 113 ? 5.139   34.873 10.419  1.00 15.88 ? 113 LEU H N    1 
ATOM   3230 C CA   . LEU B 2 113 ? 3.721   34.615 10.229  1.00 16.84 ? 113 LEU H CA   1 
ATOM   3231 C C    . LEU B 2 113 ? 3.097   35.689 9.358   1.00 18.76 ? 113 LEU H C    1 
ATOM   3232 O O    . LEU B 2 113 ? 3.327   36.874 9.572   1.00 19.56 ? 113 LEU H O    1 
ATOM   3233 C CB   . LEU B 2 113 ? 2.984   34.491 11.571  1.00 20.65 ? 113 LEU H CB   1 
ATOM   3234 C CG   . LEU B 2 113 ? 1.460   34.434 11.433  1.00 17.37 ? 113 LEU H CG   1 
ATOM   3235 C CD1  . LEU B 2 113 ? 1.025   33.037 11.127  1.00 19.59 ? 113 LEU H CD1  1 
ATOM   3236 C CD2  . LEU B 2 113 ? 0.841   34.842 12.769  1.00 23.64 ? 113 LEU H CD2  1 
ATOM   3237 H H    . LEU B 2 113 ? 5.333   35.377 11.089  1.00 19.12 ? 113 LEU H H    1 
ATOM   3238 H HA   . LEU B 2 113 ? 3.619   33.768 9.767   1.00 20.26 ? 113 LEU H HA   1 
ATOM   3239 H HB2  . LEU B 2 113 ? 3.273   33.676 12.011  1.00 24.85 ? 113 LEU H HB2  1 
ATOM   3240 H HB3  . LEU B 2 113 ? 3.204   35.260 12.120  1.00 24.85 ? 113 LEU H HB3  1 
ATOM   3241 H HG   . LEU B 2 113 ? 1.170   35.024 10.721  1.00 20.91 ? 113 LEU H HG   1 
ATOM   3242 H HD11 . LEU B 2 113 ? 0.071   33.034 10.953  1.00 23.57 ? 113 LEU H HD11 1 
ATOM   3243 H HD12 . LEU B 2 113 ? 1.505   32.721 10.345  1.00 23.57 ? 113 LEU H HD12 1 
ATOM   3244 H HD13 . LEU B 2 113 ? 1.225   32.470 11.889  1.00 23.57 ? 113 LEU H HD13 1 
ATOM   3245 H HD21 . LEU B 2 113 ? -0.123  34.753 12.710  1.00 28.43 ? 113 LEU H HD21 1 
ATOM   3246 H HD22 . LEU B 2 113 ? 1.184   34.262 13.466  1.00 28.43 ? 113 LEU H HD22 1 
ATOM   3247 H HD23 . LEU B 2 113 ? 1.078   35.763 12.958  1.00 28.43 ? 113 LEU H HD23 1 
ATOM   3248 N N    . VAL B 2 114 ? 2.351   35.255 8.353   1.00 14.83 ? 114 VAL H N    1 
ATOM   3249 C CA   . VAL B 2 114 ? 1.569   36.125 7.476   1.00 15.61 ? 114 VAL H CA   1 
ATOM   3250 C C    . VAL B 2 114 ? 0.104   35.816 7.697   1.00 17.13 ? 114 VAL H C    1 
ATOM   3251 O O    . VAL B 2 114 ? -0.317  34.673 7.538   1.00 18.27 ? 114 VAL H O    1 
ATOM   3252 C CB   . VAL B 2 114 ? 1.964   35.958 5.994   1.00 18.54 ? 114 VAL H CB   1 
ATOM   3253 C CG1  . VAL B 2 114 ? 1.165   36.929 5.130   1.00 21.37 ? 114 VAL H CG1  1 
ATOM   3254 C CG2  . VAL B 2 114 ? 3.452   36.213 5.811   1.00 17.63 ? 114 VAL H CG2  1 
ATOM   3255 H H    . VAL B 2 114 ? 2.276   34.423 8.147   1.00 17.86 ? 114 VAL H H    1 
ATOM   3256 H HA   . VAL B 2 114 ? 1.721   37.051 7.723   1.00 18.80 ? 114 VAL H HA   1 
ATOM   3257 H HB   . VAL B 2 114 ? 1.768   35.050 5.715   1.00 22.31 ? 114 VAL H HB   1 
ATOM   3258 H HG11 . VAL B 2 114 ? 1.477   36.866 4.214   1.00 25.71 ? 114 VAL H HG11 1 
ATOM   3259 H HG12 . VAL B 2 114 ? 0.226   36.694 5.177   1.00 25.71 ? 114 VAL H HG12 1 
ATOM   3260 H HG13 . VAL B 2 114 ? 1.298   37.830 5.463   1.00 25.71 ? 114 VAL H HG13 1 
ATOM   3261 H HG21 . VAL B 2 114 ? 3.636   36.342 4.867   1.00 21.22 ? 114 VAL H HG21 1 
ATOM   3262 H HG22 . VAL B 2 114 ? 3.700   37.008 6.308   1.00 21.22 ? 114 VAL H HG22 1 
ATOM   3263 H HG23 . VAL B 2 114 ? 3.946   35.447 6.143   1.00 21.22 ? 114 VAL H HG23 1 
ATOM   3264 N N    . THR B 2 115 ? -0.671  36.831 8.114   1.00 17.23 ? 115 THR H N    1 
ATOM   3265 C CA   . THR B 2 115 ? -2.108  36.720 8.282   1.00 19.32 ? 115 THR H CA   1 
ATOM   3266 C C    . THR B 2 115 ? -2.758  37.588 7.219   1.00 20.00 ? 115 THR H C    1 
ATOM   3267 O O    . THR B 2 115 ? -2.532  38.801 7.194   1.00 22.97 ? 115 THR H O    1 
ATOM   3268 C CB   . THR B 2 115 ? -2.536  37.165 9.681   1.00 19.53 ? 115 THR H CB   1 
ATOM   3269 O OG1  . THR B 2 115 ? -1.625  36.625 10.648  1.00 24.12 ? 115 THR H OG1  1 
ATOM   3270 C CG2  . THR B 2 115 ? -3.975  36.767 9.962   1.00 24.87 ? 115 THR H CG2  1 
ATOM   3271 H H    . THR B 2 115 ? -0.367  37.611 8.309   1.00 20.74 ? 115 THR H H    1 
ATOM   3272 H HA   . THR B 2 115 ? -2.391  35.799 8.164   1.00 23.24 ? 115 THR H HA   1 
ATOM   3273 H HB   . THR B 2 115 ? -2.509  38.132 9.752   1.00 23.50 ? 115 THR H HB   1 
ATOM   3274 H HG1  . THR B 2 115 ? -1.842  36.878 11.419  1.00 29.00 ? 115 THR H HG1  1 
ATOM   3275 H HG21 . THR B 2 115 ? -4.235  37.065 10.848  1.00 29.90 ? 115 THR H HG21 1 
ATOM   3276 H HG22 . THR B 2 115 ? -4.566  37.172 9.308   1.00 29.90 ? 115 THR H HG22 1 
ATOM   3277 H HG23 . THR B 2 115 ? -4.068  35.802 9.915   1.00 29.90 ? 115 THR H HG23 1 
ATOM   3278 N N    . VAL B 2 116 ? -3.588  36.970 6.386   1.00 18.69 ? 116 VAL H N    1 
ATOM   3279 C CA   . VAL B 2 116 ? -4.336  37.674 5.347   1.00 19.10 ? 116 VAL H CA   1 
ATOM   3280 C C    . VAL B 2 116 ? -5.794  37.725 5.782   1.00 17.22 ? 116 VAL H C    1 
ATOM   3281 O O    . VAL B 2 116 ? -6.507  36.718 5.695   1.00 20.08 ? 116 VAL H O    1 
ATOM   3282 C CB   . VAL B 2 116 ? -4.218  37.000 3.976   1.00 19.17 ? 116 VAL H CB   1 
ATOM   3283 C CG1  . VAL B 2 116 ? -4.910  37.861 2.933   1.00 19.66 ? 116 VAL H CG1  1 
ATOM   3284 C CG2  . VAL B 2 116 ? -2.762  36.769 3.617   1.00 19.73 ? 116 VAL H CG2  1 
ATOM   3285 H H    . VAL B 2 116 ? -3.738  36.124 6.402   1.00 22.48 ? 116 VAL H H    1 
ATOM   3286 H HA   . VAL B 2 116 ? -3.988  38.577 5.280   1.00 22.99 ? 116 VAL H HA   1 
ATOM   3287 H HB   . VAL B 2 116 ? -4.651  36.132 3.999   1.00 23.06 ? 116 VAL H HB   1 
ATOM   3288 H HG11 . VAL B 2 116 ? -4.652  37.555 2.049   1.00 23.65 ? 116 VAL H HG11 1 
ATOM   3289 H HG12 . VAL B 2 116 ? -5.870  37.782 3.044   1.00 23.65 ? 116 VAL H HG12 1 
ATOM   3290 H HG13 . VAL B 2 116 ? -4.638  38.784 3.055   1.00 23.65 ? 116 VAL H HG13 1 
ATOM   3291 H HG21 . VAL B 2 116 ? -2.708  36.462 2.699   1.00 23.73 ? 116 VAL H HG21 1 
ATOM   3292 H HG22 . VAL B 2 116 ? -2.276  37.603 3.716   1.00 23.73 ? 116 VAL H HG22 1 
ATOM   3293 H HG23 . VAL B 2 116 ? -2.392  36.098 4.213   1.00 23.73 ? 116 VAL H HG23 1 
ATOM   3294 N N    . SER B 2 117 ? -6.258  38.904 6.212   1.00 21.15 ? 117 SER H N    1 
ATOM   3295 C CA   . SER B 2 117 ? -7.612  39.068 6.716   1.00 22.62 ? 117 SER H CA   1 
ATOM   3296 C C    . SER B 2 117 ? -8.124  40.459 6.364   1.00 18.00 ? 117 SER H C    1 
ATOM   3297 O O    . SER B 2 117 ? -7.353  41.422 6.342   1.00 19.55 ? 117 SER H O    1 
ATOM   3298 C CB   . SER B 2 117 ? -7.694  38.915 8.247   1.00 24.01 ? 117 SER H CB   1 
ATOM   3299 H H    . SER B 2 117 ? -5.796  39.629 6.220   1.00 25.44 ? 117 SER H H    1 
ATOM   3300 H HA   . SER B 2 117 ? -8.165  38.394 6.292   1.00 27.21 ? 117 SER H HA   1 
ATOM   3301 N N    . SER B 2 118 ? -9.434  40.545 6.140   1.00 25.19 ? 118 SER H N    1 
ATOM   3302 C CA   . SER B 2 118 ? -10.159 41.812 6.106   1.00 28.46 ? 118 SER H CA   1 
ATOM   3303 C C    . SER B 2 118 ? -10.560 42.316 7.493   1.00 32.74 ? 118 SER H C    1 
ATOM   3304 O O    . SER B 2 118 ? -11.095 43.424 7.596   1.00 27.24 ? 118 SER H O    1 
ATOM   3305 C CB   . SER B 2 118 ? -11.452 41.679 5.275   1.00 27.86 ? 118 SER H CB   1 
ATOM   3306 O OG   . SER B 2 118 ? -11.345 40.824 4.150   1.00 40.78 ? 118 SER H OG   1 
ATOM   3307 H H    . SER B 2 118 ? -9.940  39.864 6.001   1.00 30.29 ? 118 SER H H    1 
ATOM   3308 H HA   . SER B 2 118 ? -9.577  42.463 5.685   1.00 34.21 ? 118 SER H HA   1 
ATOM   3309 H HB2  . SER B 2 118 ? -12.147 41.328 5.853   1.00 33.49 ? 118 SER H HB2  1 
ATOM   3310 H HB3  . SER B 2 118 ? -11.698 42.562 4.958   1.00 33.49 ? 118 SER H HB3  1 
ATOM   3311 H HG   . SER B 2 118 ? -12.080 40.790 3.744   1.00 48.99 ? 118 SER H HG   1 
ATOM   3312 N N    . ALA B 2 119 ? -10.378 41.525 8.548   1.00 26.82 ? 119 ALA H N    1 
ATOM   3313 C CA   . ALA B 2 119 ? -10.923 41.866 9.857   1.00 19.55 ? 119 ALA H CA   1 
ATOM   3314 C C    . ALA B 2 119 ? -10.229 43.052 10.506  1.00 23.99 ? 119 ALA H C    1 
ATOM   3315 O O    . ALA B 2 119 ? -9.045  43.312 10.295  1.00 27.00 ? 119 ALA H O    1 
ATOM   3316 C CB   . ALA B 2 119 ? -10.815 40.668 10.805  1.00 23.78 ? 119 ALA H CB   1 
ATOM   3317 H H    . ALA B 2 119 ? -9.942  40.784 8.532   1.00 32.25 ? 119 ALA H H    1 
ATOM   3318 H HA   . ALA B 2 119 ? -11.853 42.108 9.725   1.00 23.52 ? 119 ALA H HA   1 
ATOM   3319 H HB1  . ALA B 2 119 ? -11.127 40.932 11.684  1.00 28.59 ? 119 ALA H HB1  1 
ATOM   3320 H HB2  . ALA B 2 119 ? -11.362 39.944 10.463  1.00 28.59 ? 119 ALA H HB2  1 
ATOM   3321 H HB3  . ALA B 2 119 ? -9.888  40.387 10.854  1.00 28.59 ? 119 ALA H HB3  1 
ATOM   3322 N N    . SER B 2 120 ? -10.974 43.749 11.356  1.00 24.77 ? 120 SER H N    1 
ATOM   3323 C CA   . SER B 2 120 ? -10.415 44.818 12.166  1.00 24.15 ? 120 SER H CA   1 
ATOM   3324 C C    . SER B 2 120 ? -10.124 44.336 13.582  1.00 25.86 ? 120 SER H C    1 
ATOM   3325 O O    . SER B 2 120 ? -10.818 43.475 14.130  1.00 23.88 ? 120 SER H O    1 
ATOM   3326 C CB   . SER B 2 120 ? -11.367 46.022 12.205  1.00 27.88 ? 120 SER H CB   1 
ATOM   3327 O OG   . SER B 2 120 ? -11.657 46.434 10.879  1.00 29.61 ? 120 SER H OG   1 
ATOM   3328 H H    . SER B 2 120 ? -11.815 43.619 11.480  1.00 29.79 ? 120 SER H H    1 
ATOM   3329 H HA   . SER B 2 120 ? -9.574  45.105 11.778  1.00 29.04 ? 120 SER H HA   1 
ATOM   3330 H HB2  . SER B 2 120 ? -12.190 45.767 12.650  1.00 33.52 ? 120 SER H HB2  1 
ATOM   3331 H HB3  . SER B 2 120 ? -10.943 46.751 12.683  1.00 33.52 ? 120 SER H HB3  1 
ATOM   3332 H HG   . SER B 2 120 ? -12.186 47.086 10.890  1.00 35.59 ? 120 SER H HG   1 
ATOM   3333 N N    . THR B 2 121 ? -9.080  44.907 14.175  1.00 21.87 ? 121 THR H N    1 
ATOM   3334 C CA   . THR B 2 121 ? -8.739  44.561 15.545  1.00 23.29 ? 121 THR H CA   1 
ATOM   3335 C C    . THR B 2 121 ? -9.915  44.817 16.478  1.00 26.86 ? 121 THR H C    1 
ATOM   3336 O O    . THR B 2 121 ? -10.532 45.876 16.455  1.00 25.97 ? 121 THR H O    1 
ATOM   3337 C CB   . THR B 2 121 ? -7.514  45.316 16.013  1.00 25.62 ? 121 THR H CB   1 
ATOM   3338 O OG1  . THR B 2 121 ? -6.429  45.072 15.111  1.00 27.84 ? 121 THR H OG1  1 
ATOM   3339 C CG2  . THR B 2 121 ? -7.106  44.906 17.419  1.00 26.90 ? 121 THR H CG2  1 
ATOM   3340 H H    . THR B 2 121 ? -8.563  45.489 13.809  1.00 26.30 ? 121 THR H H    1 
ATOM   3341 H HA   . THR B 2 121 ? -8.526  43.616 15.578  1.00 28.01 ? 121 THR H HA   1 
ATOM   3342 H HB   . THR B 2 121 ? -7.719  46.264 16.032  1.00 30.80 ? 121 THR H HB   1 
ATOM   3343 H HG1  . THR B 2 121 ? -5.726  45.423 15.407  1.00 33.46 ? 121 THR H HG1  1 
ATOM   3344 H HG21 . THR B 2 121 ? -6.322  45.406 17.696  1.00 32.34 ? 121 THR H HG21 1 
ATOM   3345 H HG22 . THR B 2 121 ? -7.830  45.086 18.040  1.00 32.34 ? 121 THR H HG22 1 
ATOM   3346 H HG23 . THR B 2 121 ? -6.900  43.959 17.442  1.00 32.34 ? 121 THR H HG23 1 
ATOM   3347 N N    . LYS B 2 122 ? -10.217 43.817 17.300  1.00 27.76 ? 122 LYS H N    1 
ATOM   3348 C CA   . LYS B 2 122 ? -11.480 43.757 18.029  1.00 25.23 ? 122 LYS H CA   1 
ATOM   3349 C C    . LYS B 2 122 ? -11.288 42.836 19.219  1.00 28.07 ? 122 LYS H C    1 
ATOM   3350 O O    . LYS B 2 122 ? -10.859 41.686 19.053  1.00 23.48 ? 122 LYS H O    1 
ATOM   3351 C CB   . LYS B 2 122 ? -12.596 43.231 17.124  1.00 26.92 ? 122 LYS H CB   1 
ATOM   3352 C CG   . LYS B 2 122 ? -13.965 43.198 17.753  1.00 30.64 ? 122 LYS H CG   1 
ATOM   3353 C CD   . LYS B 2 122 ? -15.020 43.099 16.699  1.00 32.51 ? 122 LYS H CD   1 
ATOM   3354 H H    . LYS B 2 122 ? -9.698  43.150 17.457  1.00 33.37 ? 122 LYS H H    1 
ATOM   3355 H HA   . LYS B 2 122 ? -11.730 44.638 18.349  1.00 30.33 ? 122 LYS H HA   1 
ATOM   3356 H HB2  . LYS B 2 122 ? -12.649 43.800 16.341  1.00 32.36 ? 122 LYS H HB2  1 
ATOM   3357 H HB3  . LYS B 2 122 ? -12.375 42.324 16.861  1.00 32.36 ? 122 LYS H HB3  1 
ATOM   3358 H HG2  . LYS B 2 122 ? -14.037 42.426 18.336  1.00 36.83 ? 122 LYS H HG2  1 
ATOM   3359 H HG3  . LYS B 2 122 ? -14.110 44.011 18.261  1.00 36.83 ? 122 LYS H HG3  1 
ATOM   3360 N N    . GLY B 2 123 ? -11.606 43.333 20.412  1.00 26.70 ? 123 GLY H N    1 
ATOM   3361 C CA   . GLY B 2 123 ? -11.574 42.530 21.611  1.00 27.87 ? 123 GLY H CA   1 
ATOM   3362 C C    . GLY B 2 123 ? -12.757 41.587 21.699  1.00 22.84 ? 123 GLY H C    1 
ATOM   3363 O O    . GLY B 2 123 ? -13.833 41.836 21.161  1.00 24.49 ? 123 GLY H O    1 
ATOM   3364 H H    . GLY B 2 123 ? -11.845 44.148 20.547  1.00 32.10 ? 123 GLY H H    1 
ATOM   3365 H HA2  . GLY B 2 123 ? -10.760 42.003 21.624  1.00 33.51 ? 123 GLY H HA2  1 
ATOM   3366 H HA3  . GLY B 2 123 ? -11.587 43.111 22.388  1.00 33.51 ? 123 GLY H HA3  1 
ATOM   3367 N N    . PRO B 2 124 ? -12.595 40.487 22.417  1.00 20.99 ? 124 PRO H N    1 
ATOM   3368 C CA   . PRO B 2 124 ? -13.679 39.518 22.506  1.00 18.78 ? 124 PRO H CA   1 
ATOM   3369 C C    . PRO B 2 124 ? -14.823 39.937 23.415  1.00 22.28 ? 124 PRO H C    1 
ATOM   3370 O O    . PRO B 2 124 ? -14.675 40.715 24.371  1.00 23.78 ? 124 PRO H O    1 
ATOM   3371 C CB   . PRO B 2 124 ? -12.977 38.278 23.065  1.00 20.36 ? 124 PRO H CB   1 
ATOM   3372 C CG   . PRO B 2 124 ? -11.899 38.825 23.886  1.00 24.35 ? 124 PRO H CG   1 
ATOM   3373 C CD   . PRO B 2 124 ? -11.480 40.128 23.294  1.00 24.52 ? 124 PRO H CD   1 
ATOM   3374 H HA   . PRO B 2 124 ? -14.039 39.359 21.620  1.00 22.60 ? 124 PRO H HA   1 
ATOM   3375 H HB2  . PRO B 2 124 ? -13.596 37.755 23.600  1.00 24.49 ? 124 PRO H HB2  1 
ATOM   3376 H HB3  . PRO B 2 124 ? -12.627 37.736 22.340  1.00 24.49 ? 124 PRO H HB3  1 
ATOM   3377 H HG2  . PRO B 2 124 ? -12.224 38.957 24.791  1.00 29.28 ? 124 PRO H HG2  1 
ATOM   3378 H HG3  . PRO B 2 124 ? -11.154 38.203 23.889  1.00 29.28 ? 124 PRO H HG3  1 
ATOM   3379 H HD2  . PRO B 2 124 ? -11.359 40.796 23.986  1.00 29.49 ? 124 PRO H HD2  1 
ATOM   3380 H HD3  . PRO B 2 124 ? -10.662 40.025 22.784  1.00 29.49 ? 124 PRO H HD3  1 
ATOM   3381 N N    . SER B 2 125 ? -15.981 39.382 23.087  1.00 21.59 ? 125 SER H N    1 
ATOM   3382 C CA   . SER B 2 125 ? -17.107 39.274 24.001  1.00 23.91 ? 125 SER H CA   1 
ATOM   3383 C C    . SER B 2 125 ? -16.957 37.968 24.764  1.00 24.82 ? 125 SER H C    1 
ATOM   3384 O O    . SER B 2 125 ? -16.635 36.934 24.179  1.00 23.57 ? 125 SER H O    1 
ATOM   3385 C CB   . SER B 2 125 ? -18.423 39.274 23.225  1.00 28.18 ? 125 SER H CB   1 
ATOM   3386 O OG   . SER B 2 125 ? -18.498 40.431 22.402  1.00 30.98 ? 125 SER H OG   1 
ATOM   3387 H H    . SER B 2 125 ? -16.146 39.048 22.312  1.00 25.97 ? 125 SER H H    1 
ATOM   3388 H HA   . SER B 2 125 ? -17.131 40.021 24.620  1.00 28.76 ? 125 SER H HA   1 
ATOM   3389 H HB2  . SER B 2 125 ? -18.464 38.482 22.667  1.00 33.88 ? 125 SER H HB2  1 
ATOM   3390 H HB3  . SER B 2 125 ? -19.163 39.278 23.851  1.00 33.88 ? 125 SER H HB3  1 
ATOM   3391 H HG   . SER B 2 125 ? -19.145 40.364 21.871  1.00 37.24 ? 125 SER H HG   1 
ATOM   3392 N N    . VAL B 2 126 ? -17.211 38.008 26.063  1.00 17.73 ? 126 VAL H N    1 
ATOM   3393 C CA   . VAL B 2 126 ? -16.969 36.878 26.955  1.00 17.29 ? 126 VAL H CA   1 
ATOM   3394 C C    . VAL B 2 126 ? -18.290 36.518 27.603  1.00 19.50 ? 126 VAL H C    1 
ATOM   3395 O O    . VAL B 2 126 ? -18.900 37.346 28.300  1.00 20.64 ? 126 VAL H O    1 
ATOM   3396 C CB   . VAL B 2 126 ? -15.903 37.192 28.015  1.00 18.56 ? 126 VAL H CB   1 
ATOM   3397 C CG1  . VAL B 2 126 ? -15.641 35.974 28.911  1.00 18.76 ? 126 VAL H CG1  1 
ATOM   3398 C CG2  . VAL B 2 126 ? -14.609 37.634 27.358  1.00 21.68 ? 126 VAL H CG2  1 
ATOM   3399 H H    . VAL B 2 126 ? -17.533 38.697 26.465  1.00 21.33 ? 126 VAL H H    1 
ATOM   3400 H HA   . VAL B 2 126 ? -16.660 36.119 26.437  1.00 20.81 ? 126 VAL H HA   1 
ATOM   3401 H HB   . VAL B 2 126 ? -16.234 37.915 28.570  1.00 22.33 ? 126 VAL H HB   1 
ATOM   3402 H HG11 . VAL B 2 126 ? -14.764 36.063 29.316  1.00 22.57 ? 126 VAL H HG11 1 
ATOM   3403 H HG12 . VAL B 2 126 ? -16.322 35.938 29.601  1.00 22.57 ? 126 VAL H HG12 1 
ATOM   3404 H HG13 . VAL B 2 126 ? -15.676 35.170 28.369  1.00 22.57 ? 126 VAL H HG13 1 
ATOM   3405 H HG21 . VAL B 2 126 ? -13.923 37.720 28.039  1.00 26.07 ? 126 VAL H HG21 1 
ATOM   3406 H HG22 . VAL B 2 126 ? -14.344 36.969 26.703  1.00 26.07 ? 126 VAL H HG22 1 
ATOM   3407 H HG23 . VAL B 2 126 ? -14.752 38.489 26.923  1.00 26.07 ? 126 VAL H HG23 1 
ATOM   3408 N N    . PHE B 2 127 ? -18.733 35.293 27.374  1.00 16.15 ? 127 PHE H N    1 
ATOM   3409 C CA   . PHE B 2 127 ? -20.007 34.837 27.892  1.00 18.30 ? 127 PHE H CA   1 
ATOM   3410 C C    . PHE B 2 127 ? -19.807 33.620 28.787  1.00 20.43 ? 127 PHE H C    1 
ATOM   3411 O O    . PHE B 2 127 ? -18.920 32.796 28.533  1.00 18.44 ? 127 PHE H O    1 
ATOM   3412 C CB   . PHE B 2 127 ? -20.983 34.446 26.784  1.00 19.17 ? 127 PHE H CB   1 
ATOM   3413 C CG   . PHE B 2 127 ? -21.176 35.489 25.735  1.00 20.71 ? 127 PHE H CG   1 
ATOM   3414 C CD1  . PHE B 2 127 ? -21.871 36.661 26.036  1.00 23.06 ? 127 PHE H CD1  1 
ATOM   3415 C CD2  . PHE B 2 127 ? -20.677 35.306 24.451  1.00 22.32 ? 127 PHE H CD2  1 
ATOM   3416 C CE1  . PHE B 2 127 ? -22.045 37.627 25.095  1.00 23.88 ? 127 PHE H CE1  1 
ATOM   3417 C CE2  . PHE B 2 127 ? -20.844 36.275 23.484  1.00 26.07 ? 127 PHE H CE2  1 
ATOM   3418 C CZ   . PHE B 2 127 ? -21.528 37.443 23.796  1.00 21.89 ? 127 PHE H CZ   1 
ATOM   3419 H H    . PHE B 2 127 ? -18.307 34.702 26.916  1.00 19.44 ? 127 PHE H H    1 
ATOM   3420 H HA   . PHE B 2 127 ? -20.402 35.562 28.401  1.00 22.02 ? 127 PHE H HA   1 
ATOM   3421 H HB2  . PHE B 2 127 ? -20.649 33.647 26.346  1.00 23.06 ? 127 PHE H HB2  1 
ATOM   3422 H HB3  . PHE B 2 127 ? -21.849 34.268 27.184  1.00 23.06 ? 127 PHE H HB3  1 
ATOM   3423 H HD1  . PHE B 2 127 ? -22.220 36.782 26.889  1.00 27.74 ? 127 PHE H HD1  1 
ATOM   3424 H HD2  . PHE B 2 127 ? -20.225 34.521 24.241  1.00 26.84 ? 127 PHE H HD2  1 
ATOM   3425 H HE1  . PHE B 2 127 ? -22.503 38.408 25.307  1.00 28.72 ? 127 PHE H HE1  1 
ATOM   3426 H HE2  . PHE B 2 127 ? -20.501 36.148 22.629  1.00 31.35 ? 127 PHE H HE2  1 
ATOM   3427 H HZ   . PHE B 2 127 ? -21.645 38.102 23.151  1.00 26.33 ? 127 PHE H HZ   1 
ATOM   3428 N N    . PRO B 2 128 ? -20.619 33.470 29.837  1.00 17.75 ? 128 PRO H N    1 
ATOM   3429 C CA   . PRO B 2 128 ? -20.462 32.314 30.719  1.00 19.71 ? 128 PRO H CA   1 
ATOM   3430 C C    . PRO B 2 128 ? -20.978 31.035 30.082  1.00 21.63 ? 128 PRO H C    1 
ATOM   3431 O O    . PRO B 2 128 ? -21.977 31.032 29.356  1.00 21.08 ? 128 PRO H O    1 
ATOM   3432 C CB   . PRO B 2 128 ? -21.312 32.691 31.938  1.00 23.08 ? 128 PRO H CB   1 
ATOM   3433 C CG   . PRO B 2 128 ? -22.450 33.475 31.330  1.00 24.46 ? 128 PRO H CG   1 
ATOM   3434 C CD   . PRO B 2 128 ? -21.831 34.250 30.176  1.00 22.69 ? 128 PRO H CD   1 
ATOM   3435 H HA   . PRO B 2 128 ? -19.533 32.201 30.972  1.00 23.71 ? 128 PRO H HA   1 
ATOM   3436 H HB2  . PRO B 2 128 ? -21.632 31.893 32.386  1.00 27.75 ? 128 PRO H HB2  1 
ATOM   3437 H HB3  . PRO B 2 128 ? -20.797 33.234 32.555  1.00 27.75 ? 128 PRO H HB3  1 
ATOM   3438 H HG2  . PRO B 2 128 ? -23.135 32.868 31.011  1.00 29.41 ? 128 PRO H HG2  1 
ATOM   3439 H HG3  . PRO B 2 128 ? -22.823 34.079 31.991  1.00 29.41 ? 128 PRO H HG3  1 
ATOM   3440 H HD2  . PRO B 2 128 ? -22.439 34.286 29.421  1.00 27.29 ? 128 PRO H HD2  1 
ATOM   3441 H HD3  . PRO B 2 128 ? -21.593 35.149 30.454  1.00 27.29 ? 128 PRO H HD3  1 
ATOM   3442 N N    . LEU B 2 129 ? -20.262 29.946 30.363  1.00 18.24 ? 129 LEU H N    1 
ATOM   3443 C CA   . LEU B 2 129 ? -20.687 28.575 30.126  1.00 17.68 ? 129 LEU H CA   1 
ATOM   3444 C C    . LEU B 2 129 ? -21.037 28.054 31.519  1.00 20.20 ? 129 LEU H C    1 
ATOM   3445 O O    . LEU B 2 129 ? -20.172 27.571 32.255  1.00 19.07 ? 129 LEU H O    1 
ATOM   3446 C CB   . LEU B 2 129 ? -19.590 27.732 29.449  1.00 19.15 ? 129 LEU H CB   1 
ATOM   3447 C CG   . LEU B 2 129 ? -19.172 28.247 28.068  1.00 19.09 ? 129 LEU H CG   1 
ATOM   3448 C CD1  . LEU B 2 129 ? -17.848 27.613 27.653  1.00 19.11 ? 129 LEU H CD1  1 
ATOM   3449 C CD2  . LEU B 2 129 ? -20.295 27.922 27.072  1.00 22.94 ? 129 LEU H CD2  1 
ATOM   3450 H H    . LEU B 2 129 ? -19.477 29.983 30.713  1.00 21.95 ? 129 LEU H H    1 
ATOM   3451 H HA   . LEU B 2 129 ? -21.455 28.542 29.534  1.00 21.27 ? 129 LEU H HA   1 
ATOM   3452 H HB2  . LEU B 2 129 ? -18.803 27.734 30.016  1.00 23.04 ? 129 LEU H HB2  1 
ATOM   3453 H HB3  . LEU B 2 129 ? -19.918 26.825 29.340  1.00 23.04 ? 129 LEU H HB3  1 
ATOM   3454 H HG   . LEU B 2 129 ? -19.034 29.207 28.077  1.00 22.96 ? 129 LEU H HG   1 
ATOM   3455 H HD11 . LEU B 2 129 ? -17.595 27.952 26.780  1.00 22.99 ? 129 LEU H HD11 1 
ATOM   3456 H HD12 . LEU B 2 129 ? -17.170 27.842 28.306  1.00 22.99 ? 129 LEU H HD12 1 
ATOM   3457 H HD13 . LEU B 2 129 ? -17.958 26.650 27.614  1.00 22.99 ? 129 LEU H HD13 1 
ATOM   3458 H HD21 . LEU B 2 129 ? -20.085 28.326 26.216  1.00 27.59 ? 129 LEU H HD21 1 
ATOM   3459 H HD22 . LEU B 2 129 ? -20.362 26.959 26.975  1.00 27.59 ? 129 LEU H HD22 1 
ATOM   3460 H HD23 . LEU B 2 129 ? -21.131 28.279 27.411  1.00 27.59 ? 129 LEU H HD23 1 
ATOM   3461 N N    . ALA B 2 130 ? -22.330 28.179 31.880  1.00 25.81 ? 130 ALA H N    1 
ATOM   3462 C CA   . ALA B 2 130 ? -22.732 28.068 33.271  1.00 25.35 ? 130 ALA H CA   1 
ATOM   3463 C C    . ALA B 2 130 ? -22.846 26.607 33.694  1.00 25.43 ? 130 ALA H C    1 
ATOM   3464 O O    . ALA B 2 130 ? -23.355 25.775 32.938  1.00 28.36 ? 130 ALA H O    1 
ATOM   3465 C CB   . ALA B 2 130 ? -24.071 28.773 33.502  1.00 29.69 ? 130 ALA H CB   1 
ATOM   3466 H H    . ALA B 2 130 ? -22.979 28.326 31.335  1.00 31.03 ? 130 ALA H H    1 
ATOM   3467 H HA   . ALA B 2 130 ? -22.058 28.490 33.827  1.00 30.48 ? 130 ALA H HA   1 
ATOM   3468 H HB1  . ALA B 2 130 ? -24.322 28.675 34.434  1.00 35.69 ? 130 ALA H HB1  1 
ATOM   3469 H HB2  . ALA B 2 130 ? -23.975 29.712 33.282  1.00 35.69 ? 130 ALA H HB2  1 
ATOM   3470 H HB3  . ALA B 2 130 ? -24.744 28.366 32.934  1.00 35.69 ? 130 ALA H HB3  1 
ATOM   3471 N N    . PRO B 2 131 ? -22.390 26.275 34.912  1.00 26.55 ? 131 PRO H N    1 
ATOM   3472 C CA   . PRO B 2 131 ? -22.483 24.905 35.436  1.00 29.53 ? 131 PRO H CA   1 
ATOM   3473 C C    . PRO B 2 131 ? -23.944 24.372 35.476  1.00 37.42 ? 131 PRO H C    1 
ATOM   3474 O O    . PRO B 2 131 ? -24.829 25.184 35.821  1.00 37.08 ? 131 PRO H O    1 
ATOM   3475 C CB   . PRO B 2 131 ? -21.891 25.040 36.850  1.00 32.12 ? 131 PRO H CB   1 
ATOM   3476 C CG   . PRO B 2 131 ? -21.974 26.475 37.184  1.00 35.11 ? 131 PRO H CG   1 
ATOM   3477 C CD   . PRO B 2 131 ? -21.820 27.208 35.906  1.00 32.89 ? 131 PRO H CD   1 
ATOM   3478 H HA   . PRO B 2 131 ? -21.941 24.291 34.916  1.00 35.50 ? 131 PRO H HA   1 
ATOM   3479 H HB2  . PRO B 2 131 ? -22.411 24.510 37.474  1.00 38.60 ? 131 PRO H HB2  1 
ATOM   3480 H HB3  . PRO B 2 131 ? -20.968 24.740 36.848  1.00 38.60 ? 131 PRO H HB3  1 
ATOM   3481 H HG2  . PRO B 2 131 ? -22.836 26.666 37.586  1.00 42.19 ? 131 PRO H HG2  1 
ATOM   3482 H HG3  . PRO B 2 131 ? -21.262 26.708 37.800  1.00 42.19 ? 131 PRO H HG3  1 
ATOM   3483 H HD2  . PRO B 2 131 ? -22.317 28.041 35.923  1.00 39.52 ? 131 PRO H HD2  1 
ATOM   3484 H HD3  . PRO B 2 131 ? -20.885 27.383 35.719  1.00 39.52 ? 131 PRO H HD3  1 
ATOM   3485 N N    . GLY B 2 139 ? -20.185 13.796 40.841  1.00 39.14 ? 139 GLY H N    1 
ATOM   3486 C CA   . GLY B 2 139 ? -19.929 14.852 41.797  1.00 37.27 ? 139 GLY H CA   1 
ATOM   3487 C C    . GLY B 2 139 ? -18.976 15.871 41.213  1.00 40.77 ? 139 GLY H C    1 
ATOM   3488 O O    . GLY B 2 139 ? -18.319 16.603 41.940  1.00 39.26 ? 139 GLY H O    1 
ATOM   3489 N N    . THR B 2 140 ? -18.913 15.911 39.883  1.00 39.84 ? 140 THR H N    1 
ATOM   3490 C CA   . THR B 2 140 ? -18.039 16.819 39.148  1.00 36.56 ? 140 THR H CA   1 
ATOM   3491 C C    . THR B 2 140 ? -18.865 17.713 38.236  1.00 35.31 ? 140 THR H C    1 
ATOM   3492 O O    . THR B 2 140 ? -19.743 17.231 37.508  1.00 35.40 ? 140 THR H O    1 
ATOM   3493 C CB   . THR B 2 140 ? -17.005 16.056 38.320  1.00 37.49 ? 140 THR H CB   1 
ATOM   3494 O OG1  . THR B 2 140 ? -16.106 15.375 39.202  1.00 39.35 ? 140 THR H OG1  1 
ATOM   3495 C CG2  . THR B 2 140 ? -16.224 17.025 37.434  1.00 36.26 ? 140 THR H CG2  1 
ATOM   3496 H HA   . THR B 2 140 ? -17.573 17.380 39.788  1.00 43.93 ? 140 THR H HA   1 
ATOM   3497 H HB   . THR B 2 140 ? -17.447 15.409 37.748  1.00 45.05 ? 140 THR H HB   1 
ATOM   3498 H HG1  . THR B 2 140 ? -16.044 15.793 39.929  1.00 47.28 ? 140 THR H HG1  1 
ATOM   3499 H HG21 . THR B 2 140 ? -15.364 16.642 37.203  1.00 43.57 ? 140 THR H HG21 1 
ATOM   3500 H HG22 . THR B 2 140 ? -16.720 17.202 36.619  1.00 43.57 ? 140 THR H HG22 1 
ATOM   3501 H HG23 . THR B 2 140 ? -16.081 17.861 37.903  1.00 43.57 ? 140 THR H HG23 1 
ATOM   3502 N N    . ALA B 2 141 ? -18.580 19.012 38.282  1.00 29.84 ? 141 ALA H N    1 
ATOM   3503 C CA   . ALA B 2 141 ? -19.282 20.015 37.497  1.00 27.56 ? 141 ALA H CA   1 
ATOM   3504 C C    . ALA B 2 141 ? -18.317 20.637 36.489  1.00 20.76 ? 141 ALA H C    1 
ATOM   3505 O O    . ALA B 2 141 ? -17.138 20.815 36.785  1.00 24.56 ? 141 ALA H O    1 
ATOM   3506 C CB   . ALA B 2 141 ? -19.857 21.091 38.421  1.00 25.87 ? 141 ALA H CB   1 
ATOM   3507 H H    . ALA B 2 141 ? -17.961 19.344 38.779  1.00 35.87 ? 141 ALA H H    1 
ATOM   3508 H HA   . ALA B 2 141 ? -20.013 19.614 37.001  1.00 33.14 ? 141 ALA H HA   1 
ATOM   3509 H HB1  . ALA B 2 141 ? -20.460 21.655 37.913  1.00 31.10 ? 141 ALA H HB1  1 
ATOM   3510 H HB2  . ALA B 2 141 ? -20.338 20.661 39.145  1.00 31.10 ? 141 ALA H HB2  1 
ATOM   3511 H HB3  . ALA B 2 141 ? -19.128 21.622 38.778  1.00 31.10 ? 141 ALA H HB3  1 
ATOM   3512 N N    . ALA B 2 142 ? -18.811 20.962 35.307  1.00 22.56 ? 142 ALA H N    1 
ATOM   3513 C CA   . ALA B 2 142 ? -18.043 21.716 34.325  1.00 19.44 ? 142 ALA H CA   1 
ATOM   3514 C C    . ALA B 2 142 ? -18.606 23.119 34.156  1.00 20.19 ? 142 ALA H C    1 
ATOM   3515 O O    . ALA B 2 142 ? -19.825 23.326 34.197  1.00 21.62 ? 142 ALA H O    1 
ATOM   3516 C CB   . ALA B 2 142 ? -18.041 21.008 32.969  1.00 17.48 ? 142 ALA H CB   1 
ATOM   3517 H H    . ALA B 2 142 ? -19.602 20.754 35.043  1.00 27.13 ? 142 ALA H H    1 
ATOM   3518 H HA   . ALA B 2 142 ? -17.130 21.796 34.642  1.00 23.39 ? 142 ALA H HA   1 
ATOM   3519 H HB1  . ALA B 2 142 ? -17.454 21.486 32.363  1.00 21.04 ? 142 ALA H HB1  1 
ATOM   3520 H HB2  . ALA B 2 142 ? -17.724 20.099 33.088  1.00 21.04 ? 142 ALA H HB2  1 
ATOM   3521 H HB3  . ALA B 2 142 ? -18.945 20.999 32.616  1.00 21.04 ? 142 ALA H HB3  1 
ATOM   3522 N N    . LEU B 2 143 ? -17.710 24.078 33.973  1.00 17.52 ? 143 LEU H N    1 
ATOM   3523 C CA   . LEU B 2 143 ? -18.091 25.462 33.733  1.00 19.53 ? 143 LEU H CA   1 
ATOM   3524 C C    . LEU B 2 143 ? -17.026 26.098 32.848  1.00 15.62 ? 143 LEU H C    1 
ATOM   3525 O O    . LEU B 2 143 ? -15.973 25.511 32.601  1.00 18.18 ? 143 LEU H O    1 
ATOM   3526 C CB   . LEU B 2 143 ? -18.249 26.238 35.038  1.00 21.35 ? 143 LEU H CB   1 
ATOM   3527 C CG   . LEU B 2 143 ? -17.032 26.321 35.938  1.00 22.93 ? 143 LEU H CG   1 
ATOM   3528 C CD1  . LEU B 2 143 ? -16.287 27.655 35.687  1.00 23.22 ? 143 LEU H CD1  1 
ATOM   3529 C CD2  . LEU B 2 143 ? -17.455 26.213 37.386  1.00 33.17 ? 143 LEU H CD2  1 
ATOM   3530 H H    . LEU B 2 143 ? -16.859 23.951 33.984  1.00 21.08 ? 143 LEU H H    1 
ATOM   3531 H HA   . LEU B 2 143 ? -18.942 25.487 33.268  1.00 23.49 ? 143 LEU H HA   1 
ATOM   3532 H HB2  . LEU B 2 143 ? -18.501 27.148 34.816  1.00 25.68 ? 143 LEU H HB2  1 
ATOM   3533 H HB3  . LEU B 2 143 ? -18.954 25.815 35.554  1.00 25.68 ? 143 LEU H HB3  1 
ATOM   3534 H HG   . LEU B 2 143 ? -16.425 25.590 35.743  1.00 27.58 ? 143 LEU H HG   1 
ATOM   3535 H HD11 . LEU B 2 143 ? -15.519 27.703 36.278  1.00 27.93 ? 143 LEU H HD11 1 
ATOM   3536 H HD12 . LEU B 2 143 ? -15.995 27.685 34.763  1.00 27.93 ? 143 LEU H HD12 1 
ATOM   3537 H HD13 . LEU B 2 143 ? -16.891 28.392 35.868  1.00 27.93 ? 143 LEU H HD13 1 
ATOM   3538 H HD21 . LEU B 2 143 ? -16.679 26.341 37.952  1.00 39.87 ? 143 LEU H HD21 1 
ATOM   3539 H HD22 . LEU B 2 143 ? -18.118 26.897 37.573  1.00 39.87 ? 143 LEU H HD22 1 
ATOM   3540 H HD23 . LEU B 2 143 ? -17.835 25.334 37.539  1.00 39.87 ? 143 LEU H HD23 1 
ATOM   3541 N N    . GLY B 2 144 ? -17.300 27.303 32.361  1.00 17.40 ? 144 GLY H N    1 
ATOM   3542 C CA   . GLY B 2 144 ? -16.333 27.898 31.451  1.00 19.21 ? 144 GLY H CA   1 
ATOM   3543 C C    . GLY B 2 144 ? -16.736 29.267 30.976  1.00 18.37 ? 144 GLY H C    1 
ATOM   3544 O O    . GLY B 2 144 ? -17.717 29.847 31.433  1.00 17.81 ? 144 GLY H O    1 
ATOM   3545 H H    . GLY B 2 144 ? -18.000 27.771 32.532  1.00 20.94 ? 144 GLY H H    1 
ATOM   3546 H HA2  . GLY B 2 144 ? -15.477 27.974 31.901  1.00 23.11 ? 144 GLY H HA2  1 
ATOM   3547 H HA3  . GLY B 2 144 ? -16.232 27.326 30.675  1.00 23.11 ? 144 GLY H HA3  1 
ATOM   3548 N N    . CYS B 2 145 ? -15.898 29.811 30.084  1.00 16.55 ? 145 CYS H N    1 
ATOM   3549 C CA   . CYS B 2 145 ? -16.131 31.071 29.400  1.00 15.13 ? 145 CYS H CA   1 
ATOM   3550 C C    . CYS B 2 145 ? -15.972 30.895 27.901  1.00 19.52 ? 145 CYS H C    1 
ATOM   3551 O O    . CYS B 2 145 ? -14.995 30.299 27.431  1.00 16.55 ? 145 CYS H O    1 
ATOM   3552 C CB   . CYS B 2 145 ? -15.159 32.135 29.859  1.00 16.22 ? 145 CYS H CB   1 
ATOM   3553 S SG   . CYS B 2 145 ? -15.562 32.785 31.492  1.00 20.82 ? 145 CYS H SG   1 
ATOM   3554 H H    . CYS B 2 145 ? -15.155 29.444 29.853  1.00 19.93 ? 145 CYS H H    1 
ATOM   3555 H HA   . CYS B 2 145 ? -17.040 31.350 29.589  1.00 18.22 ? 145 CYS H HA   1 
ATOM   3556 H HB2  . CYS B 2 145 ? -14.267 31.754 29.898  1.00 19.53 ? 145 CYS H HB2  1 
ATOM   3557 H HB3  . CYS B 2 145 ? -15.176 32.873 29.229  1.00 19.53 ? 145 CYS H HB3  1 
ATOM   3558 N N    . LEU B 2 146 ? -16.930 31.428 27.166  1.00 15.83 ? 146 LEU H N    1 
ATOM   3559 C CA   . LEU B 2 146 ? -16.885 31.487 25.712  1.00 15.94 ? 146 LEU H CA   1 
ATOM   3560 C C    . LEU B 2 146 ? -16.318 32.840 25.303  1.00 18.75 ? 146 LEU H C    1 
ATOM   3561 O O    . LEU B 2 146 ? -16.824 33.882 25.732  1.00 20.85 ? 146 LEU H O    1 
ATOM   3562 C CB   . LEU B 2 146 ? -18.282 31.320 25.127  1.00 15.83 ? 146 LEU H CB   1 
ATOM   3563 C CG   . LEU B 2 146 ? -18.399 31.456 23.603  1.00 19.24 ? 146 LEU H CG   1 
ATOM   3564 C CD1  . LEU B 2 146 ? -17.556 30.517 22.783  1.00 17.69 ? 146 LEU H CD1  1 
ATOM   3565 C CD2  . LEU B 2 146 ? -19.876 31.327 23.250  1.00 19.18 ? 146 LEU H CD2  1 
ATOM   3566 H H    . LEU B 2 146 ? -17.645 31.776 27.495  1.00 19.06 ? 146 LEU H H    1 
ATOM   3567 H HA   . LEU B 2 146 ? -16.316 30.777 25.374  1.00 19.19 ? 146 LEU H HA   1 
ATOM   3568 H HB2  . LEU B 2 146 ? -18.603 30.435 25.360  1.00 19.06 ? 146 LEU H HB2  1 
ATOM   3569 H HB3  . LEU B 2 146 ? -18.856 31.995 25.520  1.00 19.06 ? 146 LEU H HB3  1 
ATOM   3570 H HG   . LEU B 2 146 ? -18.039 32.323 23.357  1.00 23.15 ? 146 LEU H HG   1 
ATOM   3571 H HD11 . LEU B 2 146 ? -17.803 30.605 21.849  1.00 21.29 ? 146 LEU H HD11 1 
ATOM   3572 H HD12 . LEU B 2 146 ? -16.621 30.747 22.901  1.00 21.29 ? 146 LEU H HD12 1 
ATOM   3573 H HD13 . LEU B 2 146 ? -17.713 29.608 23.083  1.00 21.29 ? 146 LEU H HD13 1 
ATOM   3574 H HD21 . LEU B 2 146 ? -19.978 31.394 22.288  1.00 23.07 ? 146 LEU H HD21 1 
ATOM   3575 H HD22 . LEU B 2 146 ? -20.200 30.465 23.558  1.00 23.07 ? 146 LEU H HD22 1 
ATOM   3576 H HD23 . LEU B 2 146 ? -20.369 32.040 23.686  1.00 23.07 ? 146 LEU H HD23 1 
ATOM   3577 N N    . VAL B 2 147 ? -15.212 32.831 24.569  1.00 13.26 ? 147 VAL H N    1 
ATOM   3578 C CA   . VAL B 2 147 ? -14.436 34.027 24.243  1.00 14.01 ? 147 VAL H CA   1 
ATOM   3579 C C    . VAL B 2 147 ? -14.615 34.239 22.752  1.00 21.46 ? 147 VAL H C    1 
ATOM   3580 O O    . VAL B 2 147 ? -13.920 33.609 21.955  1.00 20.96 ? 147 VAL H O    1 
ATOM   3581 C CB   . VAL B 2 147 ? -12.958 33.886 24.633  1.00 19.85 ? 147 VAL H CB   1 
ATOM   3582 C CG1  . VAL B 2 147 ? -12.197 35.167 24.310  1.00 20.20 ? 147 VAL H CG1  1 
ATOM   3583 C CG2  . VAL B 2 147 ? -12.854 33.534 26.136  1.00 18.44 ? 147 VAL H CG2  1 
ATOM   3584 H H    . VAL B 2 147 ? -14.875 32.115 24.233  1.00 15.98 ? 147 VAL H H    1 
ATOM   3585 H HA   . VAL B 2 147 ? -14.791 34.794 24.718  1.00 16.87 ? 147 VAL H HA   1 
ATOM   3586 H HB   . VAL B 2 147 ? -12.550 33.170 24.121  1.00 23.88 ? 147 VAL H HB   1 
ATOM   3587 H HG11 . VAL B 2 147 ? -11.296 35.096 24.663  1.00 24.30 ? 147 VAL H HG11 1 
ATOM   3588 H HG12 . VAL B 2 147 ? -12.167 35.282 23.348  1.00 24.30 ? 147 VAL H HG12 1 
ATOM   3589 H HG13 . VAL B 2 147 ? -12.654 35.918 24.719  1.00 24.30 ? 147 VAL H HG13 1 
ATOM   3590 H HG21 . VAL B 2 147 ? -11.928 33.611 26.415  1.00 22.19 ? 147 VAL H HG21 1 
ATOM   3591 H HG22 . VAL B 2 147 ? -13.404 34.151 26.643  1.00 22.19 ? 147 VAL H HG22 1 
ATOM   3592 H HG23 . VAL B 2 147 ? -13.166 32.626 26.270  1.00 22.19 ? 147 VAL H HG23 1 
ATOM   3593 N N    . LYS B 2 148 ? -15.577 35.086 22.374  1.00 19.94 ? 148 LYS H N    1 
ATOM   3594 C CA   . LYS B 2 148 ? -16.097 35.112 21.015  1.00 20.54 ? 148 LYS H CA   1 
ATOM   3595 C C    . LYS B 2 148 ? -15.750 36.407 20.304  1.00 18.78 ? 148 LYS H C    1 
ATOM   3596 O O    . LYS B 2 148 ? -15.752 37.485 20.902  1.00 18.80 ? 148 LYS H O    1 
ATOM   3597 C CB   . LYS B 2 148 ? -17.624 34.950 21.000  1.00 20.76 ? 148 LYS H CB   1 
ATOM   3598 C CG   . LYS B 2 148 ? -18.151 34.397 19.689  1.00 27.32 ? 148 LYS H CG   1 
ATOM   3599 C CD   . LYS B 2 148 ? -19.604 33.955 19.800  1.00 25.05 ? 148 LYS H CD   1 
ATOM   3600 C CE   . LYS B 2 148 ? -20.158 33.380 18.494  1.00 27.37 ? 148 LYS H CE   1 
ATOM   3601 N NZ   . LYS B 2 148 ? -19.867 34.237 17.324  1.00 36.40 ? 148 LYS H NZ   1 
ATOM   3602 H H    . LYS B 2 148 ? -15.945 35.660 22.898  1.00 23.99 ? 148 LYS H H    1 
ATOM   3603 H HA   . LYS B 2 148 ? -15.682 34.381 20.530  1.00 24.71 ? 148 LYS H HA   1 
ATOM   3604 H HB2  . LYS B 2 148 ? -17.882 34.339 21.708  1.00 24.97 ? 148 LYS H HB2  1 
ATOM   3605 H HB3  . LYS B 2 148 ? -18.033 35.818 21.145  1.00 24.97 ? 148 LYS H HB3  1 
ATOM   3606 H HG2  . LYS B 2 148 ? -18.096 35.085 19.007  1.00 32.85 ? 148 LYS H HG2  1 
ATOM   3607 H HG3  . LYS B 2 148 ? -17.620 33.628 19.430  1.00 32.85 ? 148 LYS H HG3  1 
ATOM   3608 H HD2  . LYS B 2 148 ? -19.672 33.268 20.481  1.00 30.12 ? 148 LYS H HD2  1 
ATOM   3609 H HD3  . LYS B 2 148 ? -20.148 34.719 20.044  1.00 30.12 ? 148 LYS H HD3  1 
ATOM   3610 H HE2  . LYS B 2 148 ? -19.758 32.511 18.336  1.00 32.91 ? 148 LYS H HE2  1 
ATOM   3611 H HE3  . LYS B 2 148 ? -21.121 33.294 18.571  1.00 32.91 ? 148 LYS H HE3  1 
ATOM   3612 H HZ1  . LYS B 2 148 ? -20.218 33.878 16.589  1.00 43.75 ? 148 LYS H HZ1  1 
ATOM   3613 H HZ2  . LYS B 2 148 ? -20.216 35.047 17.445  1.00 43.75 ? 148 LYS H HZ2  1 
ATOM   3614 H HZ3  . LYS B 2 148 ? -18.987 34.315 17.215  1.00 43.75 ? 148 LYS H HZ3  1 
ATOM   3615 N N    . ASP B 2 149 ? -15.476 36.268 19.009  1.00 21.22 ? 149 ASP H N    1 
ATOM   3616 C CA   . ASP B 2 149 ? -15.401 37.371 18.057  1.00 21.94 ? 149 ASP H CA   1 
ATOM   3617 C C    . ASP B 2 149 ? -14.287 38.360 18.364  1.00 21.62 ? 149 ASP H C    1 
ATOM   3618 O O    . ASP B 2 149 ? -14.505 39.562 18.555  1.00 23.87 ? 149 ASP H O    1 
ATOM   3619 C CB   . ASP B 2 149 ? -16.742 38.101 17.990  1.00 22.61 ? 149 ASP H CB   1 
ATOM   3620 C CG   . ASP B 2 149 ? -17.840 37.272 17.379  1.00 27.37 ? 149 ASP H CG   1 
ATOM   3621 O OD1  . ASP B 2 149 ? -17.524 36.268 16.694  1.00 23.50 ? 149 ASP H OD1  1 
ATOM   3622 O OD2  . ASP B 2 149 ? -19.038 37.634 17.568  1.00 25.97 ? 149 ASP H OD2  1 
ATOM   3623 H H    . ASP B 2 149 ? -15.323 35.507 18.638  1.00 25.53 ? 149 ASP H H    1 
ATOM   3624 H HA   . ASP B 2 149 ? -15.195 36.989 17.190  1.00 26.39 ? 149 ASP H HA   1 
ATOM   3625 H HB2  . ASP B 2 149 ? -17.015 38.340 18.890  1.00 27.19 ? 149 ASP H HB2  1 
ATOM   3626 H HB3  . ASP B 2 149 ? -16.638 38.901 17.452  1.00 27.19 ? 149 ASP H HB3  1 
ATOM   3627 N N    . TYR B 2 150 ? -13.051 37.875 18.336  1.00 16.75 ? 150 TYR H N    1 
ATOM   3628 C CA   . TYR B 2 150 ? -11.905 38.761 18.470  1.00 17.70 ? 150 TYR H CA   1 
ATOM   3629 C C    . TYR B 2 150 ? -10.981 38.575 17.274  1.00 21.89 ? 150 TYR H C    1 
ATOM   3630 O O    . TYR B 2 150 ? -11.104 37.598 16.524  1.00 19.86 ? 150 TYR H O    1 
ATOM   3631 C CB   . TYR B 2 150 ? -11.123 38.510 19.765  1.00 20.69 ? 150 TYR H CB   1 
ATOM   3632 C CG   . TYR B 2 150 ? -10.496 37.143 19.844  1.00 21.98 ? 150 TYR H CG   1 
ATOM   3633 C CD1  . TYR B 2 150 ? -11.223 36.069 20.329  1.00 20.32 ? 150 TYR H CD1  1 
ATOM   3634 C CD2  . TYR B 2 150 ? -9.182  36.938 19.465  1.00 23.43 ? 150 TYR H CD2  1 
ATOM   3635 C CE1  . TYR B 2 150 ? -10.666 34.785 20.408  1.00 20.94 ? 150 TYR H CE1  1 
ATOM   3636 C CE2  . TYR B 2 150 ? -8.601  35.668 19.555  1.00 20.63 ? 150 TYR H CE2  1 
ATOM   3637 C CZ   . TYR B 2 150 ? -9.367  34.593 20.021  1.00 22.46 ? 150 TYR H CZ   1 
ATOM   3638 O OH   . TYR B 2 150 ? -8.798  33.339 20.115  1.00 21.49 ? 150 TYR H OH   1 
ATOM   3639 H H    . TYR B 2 150 ? -12.854 37.044 18.240  1.00 20.16 ? 150 TYR H H    1 
ATOM   3640 H HA   . TYR B 2 150 ? -12.219 39.678 18.492  1.00 21.30 ? 150 TYR H HA   1 
ATOM   3641 H HB2  . TYR B 2 150 ? -10.411 39.166 19.830  1.00 24.88 ? 150 TYR H HB2  1 
ATOM   3642 H HB3  . TYR B 2 150 ? -11.728 38.602 20.517  1.00 24.88 ? 150 TYR H HB3  1 
ATOM   3643 H HD1  . TYR B 2 150 ? -12.100 36.203 20.607  1.00 24.44 ? 150 TYR H HD1  1 
ATOM   3644 H HD2  . TYR B 2 150 ? -8.678  37.653 19.147  1.00 28.18 ? 150 TYR H HD2  1 
ATOM   3645 H HE1  . TYR B 2 150 ? -11.174 34.072 20.721  1.00 25.19 ? 150 TYR H HE1  1 
ATOM   3646 H HE2  . TYR B 2 150 ? -7.713  35.540 19.307  1.00 24.82 ? 150 TYR H HE2  1 
ATOM   3647 H HH   . TYR B 2 150 ? -8.005  33.362 19.837  1.00 25.85 ? 150 TYR H HH   1 
ATOM   3648 N N    . PHE B 2 151 ? -10.073 39.550 17.106  1.00 20.07 ? 151 PHE H N    1 
ATOM   3649 C CA   . PHE B 2 151 ? -9.055  39.542 16.051  1.00 19.68 ? 151 PHE H CA   1 
ATOM   3650 C C    . PHE B 2 151 ? -8.011  40.584 16.413  1.00 22.24 ? 151 PHE H C    1 
ATOM   3651 O O    . PHE B 2 151 ? -8.375  41.654 16.926  1.00 23.18 ? 151 PHE H O    1 
ATOM   3652 C CB   . PHE B 2 151 ? -9.653  39.852 14.674  1.00 20.21 ? 151 PHE H CB   1 
ATOM   3653 C CG   . PHE B 2 151 ? -8.647  39.874 13.574  1.00 24.42 ? 151 PHE H CG   1 
ATOM   3654 C CD1  . PHE B 2 151 ? -8.340  38.708 12.885  1.00 24.21 ? 151 PHE H CD1  1 
ATOM   3655 C CD2  . PHE B 2 151 ? -7.982  41.037 13.251  1.00 23.24 ? 151 PHE H CD2  1 
ATOM   3656 C CE1  . PHE B 2 151 ? -7.375  38.717 11.869  1.00 21.77 ? 151 PHE H CE1  1 
ATOM   3657 C CE2  . PHE B 2 151 ? -7.033  41.058 12.231  1.00 26.69 ? 151 PHE H CE2  1 
ATOM   3658 C CZ   . PHE B 2 151 ? -6.732  39.884 11.543  1.00 24.62 ? 151 PHE H CZ   1 
ATOM   3659 H H    . PHE B 2 151 ? -10.028 40.247 17.608  1.00 24.15 ? 151 PHE H H    1 
ATOM   3660 H HA   . PHE B 2 151 ? -8.638  38.668 16.005  1.00 23.68 ? 151 PHE H HA   1 
ATOM   3661 H HB2  . PHE B 2 151 ? -10.311 39.172 14.460  1.00 24.31 ? 151 PHE H HB2  1 
ATOM   3662 H HB3  . PHE B 2 151 ? -10.076 40.725 14.706  1.00 24.31 ? 151 PHE H HB3  1 
ATOM   3663 H HD1  . PHE B 2 151 ? -8.778  37.916 13.099  1.00 29.11 ? 151 PHE H HD1  1 
ATOM   3664 H HD2  . PHE B 2 151 ? -8.169  41.818 13.721  1.00 27.95 ? 151 PHE H HD2  1 
ATOM   3665 H HE1  . PHE B 2 151 ? -7.170  37.932 11.415  1.00 26.19 ? 151 PHE H HE1  1 
ATOM   3666 H HE2  . PHE B 2 151 ? -6.603  41.852 12.010  1.00 32.08 ? 151 PHE H HE2  1 
ATOM   3667 H HZ   . PHE B 2 151 ? -6.097  39.892 10.865  1.00 29.61 ? 151 PHE H HZ   1 
ATOM   3668 N N    . PRO B 2 152 ? -6.730  40.333 16.170  1.00 22.71 ? 152 PRO H N    1 
ATOM   3669 C CA   . PRO B 2 152 ? -6.117  39.083 15.717  1.00 24.24 ? 152 PRO H CA   1 
ATOM   3670 C C    . PRO B 2 152 ? -5.896  38.139 16.875  1.00 24.42 ? 152 PRO H C    1 
ATOM   3671 O O    . PRO B 2 152 ? -6.193  38.469 18.012  1.00 22.17 ? 152 PRO H O    1 
ATOM   3672 C CB   . PRO B 2 152 ? -4.764  39.542 15.155  1.00 22.84 ? 152 PRO H CB   1 
ATOM   3673 C CG   . PRO B 2 152 ? -4.547  40.974 15.688  1.00 28.83 ? 152 PRO H CG   1 
ATOM   3674 C CD   . PRO B 2 152 ? -5.697  41.288 16.587  1.00 23.89 ? 152 PRO H CD   1 
ATOM   3675 H HA   . PRO B 2 152 ? -6.655  38.677 15.019  1.00 29.14 ? 152 PRO H HA   1 
ATOM   3676 H HB2  . PRO B 2 152 ? -4.063  38.949 15.468  1.00 27.47 ? 152 PRO H HB2  1 
ATOM   3677 H HB3  . PRO B 2 152 ? -4.795  39.537 14.186  1.00 27.47 ? 152 PRO H HB3  1 
ATOM   3678 H HG2  . PRO B 2 152 ? -3.712  41.011 16.180  1.00 34.66 ? 152 PRO H HG2  1 
ATOM   3679 H HG3  . PRO B 2 152 ? -4.522  41.594 14.943  1.00 34.66 ? 152 PRO H HG3  1 
ATOM   3680 H HD2  . PRO B 2 152 ? -5.455  41.149 17.516  1.00 28.73 ? 152 PRO H HD2  1 
ATOM   3681 H HD3  . PRO B 2 152 ? -5.998  42.200 16.456  1.00 28.73 ? 152 PRO H HD3  1 
ATOM   3682 N N    . GLU B 2 153 ? -5.212  37.034 16.653  1.00 22.43 ? 153 GLU H N    1 
ATOM   3683 C CA   . GLU B 2 153 ? -4.773  36.223 17.769  1.00 25.66 ? 153 GLU H CA   1 
ATOM   3684 C C    . GLU B 2 153 ? -3.593  36.967 18.397  1.00 26.97 ? 153 GLU H C    1 
ATOM   3685 O O    . GLU B 2 153 ? -2.972  37.771 17.748  1.00 27.85 ? 153 GLU H O    1 
ATOM   3686 C CB   . GLU B 2 153 ? -4.331  34.844 17.299  1.00 23.88 ? 153 GLU H CB   1 
ATOM   3687 C CG   . GLU B 2 153 ? -5.458  34.020 16.719  1.00 26.78 ? 153 GLU H CG   1 
ATOM   3688 C CD   . GLU B 2 153 ? -5.166  32.543 16.767  1.00 35.01 ? 153 GLU H CD   1 
ATOM   3689 O OE1  . GLU B 2 153 ? -5.364  31.932 17.824  1.00 33.30 ? 153 GLU H OE1  1 
ATOM   3690 O OE2  . GLU B 2 153 ? -4.718  32.001 15.745  1.00 36.24 ? 153 GLU H OE2  1 
ATOM   3691 H H    . GLU B 2 153 ? -4.992  36.721 15.881  1.00 26.98 ? 153 GLU H H    1 
ATOM   3692 H HA   . GLU B 2 153 ? -5.493  36.120 18.425  1.00 30.85 ? 153 GLU H HA   1 
ATOM   3693 H HB2  . GLU B 2 153 ? -3.654  34.951 16.614  1.00 28.72 ? 153 GLU H HB2  1 
ATOM   3694 H HB3  . GLU B 2 153 ? -3.965  34.357 18.053  1.00 28.72 ? 153 GLU H HB3  1 
ATOM   3695 H HG2  . GLU B 2 153 ? -6.264  34.188 17.231  1.00 32.20 ? 153 GLU H HG2  1 
ATOM   3696 H HG3  . GLU B 2 153 ? -5.595  34.274 15.792  1.00 32.20 ? 153 GLU H HG3  1 
ATOM   3697 N N    . PRO B 2 154 ? -3.292  36.715 19.664  1.00 23.27 ? 154 PRO H N    1 
ATOM   3698 C CA   . PRO B 2 154 ? -3.874  35.727 20.558  1.00 25.65 ? 154 PRO H CA   1 
ATOM   3699 C C    . PRO B 2 154 ? -4.673  36.252 21.689  1.00 22.66 ? 154 PRO H C    1 
ATOM   3700 O O    . PRO B 2 154 ? -4.648  37.436 21.929  1.00 25.52 ? 154 PRO H O    1 
ATOM   3701 C CB   . PRO B 2 154 ? -2.638  35.143 21.212  1.00 29.15 ? 154 PRO H CB   1 
ATOM   3702 C CG   . PRO B 2 154 ? -1.729  36.317 21.356  1.00 29.21 ? 154 PRO H CG   1 
ATOM   3703 C CD   . PRO B 2 154 ? -2.106  37.318 20.290  1.00 28.13 ? 154 PRO H CD   1 
ATOM   3704 H HA   . PRO B 2 154 ? -4.369  35.029 20.084  1.00 30.84 ? 154 PRO H HA   1 
ATOM   3705 H HB2  . PRO B 2 154 ? -2.870  34.773 22.078  1.00 35.04 ? 154 PRO H HB2  1 
ATOM   3706 H HB3  . PRO B 2 154 ? -2.251  34.469 20.635  1.00 35.04 ? 154 PRO H HB3  1 
ATOM   3707 H HG2  . PRO B 2 154 ? -1.854  36.703 22.237  1.00 35.11 ? 154 PRO H HG2  1 
ATOM   3708 H HG3  . PRO B 2 154 ? -0.812  36.027 21.240  1.00 35.11 ? 154 PRO H HG3  1 
ATOM   3709 H HD2  . PRO B 2 154 ? -2.340  38.171 20.691  1.00 33.82 ? 154 PRO H HD2  1 
ATOM   3710 H HD3  . PRO B 2 154 ? -1.387  37.408 19.648  1.00 33.82 ? 154 PRO H HD3  1 
ATOM   3711 N N    . VAL B 2 155 ? -5.376  35.376 22.369  1.00 24.94 ? 155 VAL H N    1 
ATOM   3712 C CA   . VAL B 2 155 ? -6.039  35.723 23.592  1.00 22.79 ? 155 VAL H CA   1 
ATOM   3713 C C    . VAL B 2 155 ? -5.456  34.825 24.674  1.00 25.26 ? 155 VAL H C    1 
ATOM   3714 O O    . VAL B 2 155 ? -5.063  33.731 24.382  1.00 22.14 ? 155 VAL H O    1 
ATOM   3715 C CB   . VAL B 2 155 ? -7.553  35.497 23.559  1.00 24.97 ? 155 VAL H CB   1 
ATOM   3716 C CG1  . VAL B 2 155 ? -8.126  35.445 24.961  1.00 36.50 ? 155 VAL H CG1  1 
ATOM   3717 C CG2  . VAL B 2 155 ? -8.224  36.621 22.801  1.00 27.43 ? 155 VAL H CG2  1 
ATOM   3718 H H    . VAL B 2 155 ? -5.488  34.557 22.135  1.00 29.99 ? 155 VAL H H    1 
ATOM   3719 H HA   . VAL B 2 155 ? -5.873  36.657 23.838  1.00 27.40 ? 155 VAL H HA   1 
ATOM   3720 H HB   . VAL B 2 155 ? -7.748  34.652 23.105  1.00 30.02 ? 155 VAL H HB   1 
ATOM   3721 H HG11 . VAL B 2 155 ? -9.074  35.585 24.904  1.00 43.86 ? 155 VAL H HG11 1 
ATOM   3722 H HG12 . VAL B 2 155 ? -7.949  34.588 25.358  1.00 43.86 ? 155 VAL H HG12 1 
ATOM   3723 H HG13 . VAL B 2 155 ? -7.732  36.144 25.488  1.00 43.86 ? 155 VAL H HG13 1 
ATOM   3724 H HG21 . VAL B 2 155 ? -9.123  36.363 22.580  1.00 32.98 ? 155 VAL H HG21 1 
ATOM   3725 H HG22 . VAL B 2 155 ? -8.229  37.403 23.357  1.00 32.98 ? 155 VAL H HG22 1 
ATOM   3726 H HG23 . VAL B 2 155 ? -7.723  36.793 22.000  1.00 32.98 ? 155 VAL H HG23 1 
ATOM   3727 N N    . THR B 2 156 ? -5.351  35.315 25.898  1.00 20.03 ? 156 THR H N    1 
ATOM   3728 C CA   . THR B 2 156 ? -4.977  34.467 27.024  1.00 23.10 ? 156 THR H CA   1 
ATOM   3729 C C    . THR B 2 156 ? -6.150  34.374 27.995  1.00 21.26 ? 156 THR H C    1 
ATOM   3730 O O    . THR B 2 156 ? -6.933  35.322 28.137  1.00 19.19 ? 156 THR H O    1 
ATOM   3731 C CB   . THR B 2 156 ? -3.754  34.997 27.759  1.00 25.49 ? 156 THR H CB   1 
ATOM   3732 O OG1  . THR B 2 156 ? -3.919  36.385 28.007  1.00 32.24 ? 156 THR H OG1  1 
ATOM   3733 C CG2  . THR B 2 156 ? -2.519  34.819 26.887  1.00 25.51 ? 156 THR H CG2  1 
ATOM   3734 H H    . THR B 2 156 ? -5.530  36.130 26.109  1.00 24.10 ? 156 THR H H    1 
ATOM   3735 H HA   . THR B 2 156 ? -4.763  33.579 26.697  1.00 27.78 ? 156 THR H HA   1 
ATOM   3736 H HB   . THR B 2 156 ? -3.641  34.518 28.595  1.00 30.65 ? 156 THR H HB   1 
ATOM   3737 H HG1  . THR B 2 156 ? -3.175  36.736 28.176  1.00 38.75 ? 156 THR H HG1  1 
ATOM   3738 H HG21 . THR B 2 156 ? -1.753  35.244 27.305  1.00 30.68 ? 156 THR H HG21 1 
ATOM   3739 H HG22 . THR B 2 156 ? -2.329  33.875 26.768  1.00 30.68 ? 156 THR H HG22 1 
ATOM   3740 H HG23 . THR B 2 156 ? -2.666  35.223 26.017  1.00 30.68 ? 156 THR H HG23 1 
ATOM   3741 N N    . VAL B 2 157 ? -6.263  33.238 28.684  1.00 17.88 ? 157 VAL H N    1 
ATOM   3742 C CA   . VAL B 2 157 ? -7.319  33.055 29.672  1.00 19.17 ? 157 VAL H CA   1 
ATOM   3743 C C    . VAL B 2 157 ? -6.696  32.441 30.915  1.00 17.78 ? 157 VAL H C    1 
ATOM   3744 O O    . VAL B 2 157 ? -5.938  31.473 30.823  1.00 25.28 ? 157 VAL H O    1 
ATOM   3745 C CB   . VAL B 2 157 ? -8.482  32.180 29.163  1.00 18.39 ? 157 VAL H CB   1 
ATOM   3746 C CG1  . VAL B 2 157 ? -9.605  32.104 30.217  1.00 16.06 ? 157 VAL H CG1  1 
ATOM   3747 C CG2  . VAL B 2 157 ? -8.965  32.687 27.815  1.00 21.14 ? 157 VAL H CG2  1 
ATOM   3748 H H    . VAL B 2 157 ? -5.740  32.561 28.594  1.00 21.52 ? 157 VAL H H    1 
ATOM   3749 H HA   . VAL B 2 157 ? -7.688  33.924 29.897  1.00 23.06 ? 157 VAL H HA   1 
ATOM   3750 H HB   . VAL B 2 157 ? -8.177  31.269 29.027  1.00 22.13 ? 157 VAL H HB   1 
ATOM   3751 H HG11 . VAL B 2 157 ? -10.421 31.801 29.789  1.00 19.33 ? 157 VAL H HG11 1 
ATOM   3752 H HG12 . VAL B 2 157 ? -9.344  31.480 30.912  1.00 19.33 ? 157 VAL H HG12 1 
ATOM   3753 H HG13 . VAL B 2 157 ? -9.740  32.986 30.598  1.00 19.33 ? 157 VAL H HG13 1 
ATOM   3754 H HG21 . VAL B 2 157 ? -9.757  32.190 27.556  1.00 25.43 ? 157 VAL H HG21 1 
ATOM   3755 H HG22 . VAL B 2 157 ? -9.176  33.631 27.890  1.00 25.43 ? 157 VAL H HG22 1 
ATOM   3756 H HG23 . VAL B 2 157 ? -8.263  32.556 27.159  1.00 25.43 ? 157 VAL H HG23 1 
ATOM   3757 N N    . SER B 2 158 ? -6.990  33.023 32.069  1.00 17.14 ? 158 SER H N    1 
ATOM   3758 C CA   . SER B 2 158 ? -6.707  32.382 33.339  1.00 19.97 ? 158 SER H CA   1 
ATOM   3759 C C    . SER B 2 158 ? -8.008  32.303 34.123  1.00 19.66 ? 158 SER H C    1 
ATOM   3760 O O    . SER B 2 158 ? -9.033  32.870 33.729  1.00 17.65 ? 158 SER H O    1 
ATOM   3761 C CB   . SER B 2 158 ? -5.636  33.132 34.116  1.00 28.08 ? 158 SER H CB   1 
ATOM   3762 O OG   . SER B 2 158 ? -6.121  34.418 34.413  1.00 22.08 ? 158 SER H OG   1 
ATOM   3763 H H    . SER B 2 158 ? -7.357  33.798 32.140  1.00 20.63 ? 158 SER H H    1 
ATOM   3764 H HA   . SER B 2 158 ? -6.377  31.481 33.198  1.00 24.03 ? 158 SER H HA   1 
ATOM   3765 H HB2  . SER B 2 158 ? -5.442  32.660 34.941  1.00 33.76 ? 158 SER H HB2  1 
ATOM   3766 H HB3  . SER B 2 158 ? -4.833  33.204 33.578  1.00 33.76 ? 158 SER H HB3  1 
ATOM   3767 H HG   . SER B 2 158 ? -5.495  34.904 34.691  1.00 26.56 ? 158 SER H HG   1 
ATOM   3768 N N    . TRP B 2 159 ? -7.972  31.546 35.211  1.00 17.55 ? 159 TRP H N    1 
ATOM   3769 C CA   . TRP B 2 159 ? -9.112  31.380 36.100  1.00 16.23 ? 159 TRP H CA   1 
ATOM   3770 C C    . TRP B 2 159 ? -8.681  31.811 37.491  1.00 23.40 ? 159 TRP H C    1 
ATOM   3771 O O    . TRP B 2 159 ? -7.591  31.444 37.960  1.00 21.85 ? 159 TRP H O    1 
ATOM   3772 C CB   . TRP B 2 159 ? -9.602  29.941 36.110  1.00 16.40 ? 159 TRP H CB   1 
ATOM   3773 C CG   . TRP B 2 159 ? -10.345 29.607 34.872  1.00 16.66 ? 159 TRP H CG   1 
ATOM   3774 C CD1  . TRP B 2 159 ? -9.828  29.152 33.714  1.00 17.82 ? 159 TRP H CD1  1 
ATOM   3775 C CD2  . TRP B 2 159 ? -11.747 29.764 34.658  1.00 17.41 ? 159 TRP H CD2  1 
ATOM   3776 N NE1  . TRP B 2 159 ? -10.828 28.966 32.775  1.00 18.13 ? 159 TRP H NE1  1 
ATOM   3777 C CE2  . TRP B 2 159 ? -12.022 29.340 33.343  1.00 17.41 ? 159 TRP H CE2  1 
ATOM   3778 C CE3  . TRP B 2 159 ? -12.800 30.188 35.466  1.00 16.40 ? 159 TRP H CE3  1 
ATOM   3779 C CZ2  . TRP B 2 159 ? -13.288 29.360 32.816  1.00 14.42 ? 159 TRP H CZ2  1 
ATOM   3780 C CZ3  . TRP B 2 159 ? -14.052 30.207 34.952  1.00 15.94 ? 159 TRP H CZ3  1 
ATOM   3781 C CH2  . TRP B 2 159 ? -14.301 29.790 33.638  1.00 17.62 ? 159 TRP H CH2  1 
ATOM   3782 H H    . TRP B 2 159 ? -7.278  31.105 35.462  1.00 21.12 ? 159 TRP H H    1 
ATOM   3783 H HA   . TRP B 2 159 ? -9.853  31.936 35.811  1.00 19.54 ? 159 TRP H HA   1 
ATOM   3784 H HB2  . TRP B 2 159 ? -8.840  29.345 36.178  1.00 19.74 ? 159 TRP H HB2  1 
ATOM   3785 H HB3  . TRP B 2 159 ? -10.195 29.810 36.866  1.00 19.74 ? 159 TRP H HB3  1 
ATOM   3786 H HD1  . TRP B 2 159 ? -8.925  28.987 33.566  1.00 21.45 ? 159 TRP H HD1  1 
ATOM   3787 H HE1  . TRP B 2 159 ? -10.721 28.669 31.975  1.00 21.81 ? 159 TRP H HE1  1 
ATOM   3788 H HE3  . TRP B 2 159 ? -12.645 30.453 36.344  1.00 19.74 ? 159 TRP H HE3  1 
ATOM   3789 H HZ2  . TRP B 2 159 ? -13.453 29.094 31.940  1.00 17.37 ? 159 TRP H HZ2  1 
ATOM   3790 H HZ3  . TRP B 2 159 ? -14.758 30.502 35.480  1.00 19.19 ? 159 TRP H HZ3  1 
ATOM   3791 H HH2  . TRP B 2 159 ? -15.173 29.804 33.315  1.00 21.21 ? 159 TRP H HH2  1 
ATOM   3792 N N    . ASN B 2 160 ? -9.533  32.597 38.129  1.00 18.66 ? 160 ASN H N    1 
ATOM   3793 C CA   . ASN B 2 160 ? -9.270  33.164 39.445  1.00 19.67 ? 160 ASN H CA   1 
ATOM   3794 C C    . ASN B 2 160 ? -7.855  33.719 39.519  1.00 22.00 ? 160 ASN H C    1 
ATOM   3795 O O    . ASN B 2 160 ? -7.070  33.380 40.404  1.00 20.52 ? 160 ASN H O    1 
ATOM   3796 C CB   . ASN B 2 160 ? -9.507  32.136 40.537  1.00 21.17 ? 160 ASN H CB   1 
ATOM   3797 C CG   . ASN B 2 160 ? -10.978 31.760 40.628  1.00 18.74 ? 160 ASN H CG   1 
ATOM   3798 O OD1  . ASN B 2 160 ? -11.837 32.470 40.085  1.00 21.40 ? 160 ASN H OD1  1 
ATOM   3799 N ND2  . ASN B 2 160 ? -11.281 30.700 41.367  1.00 21.63 ? 160 ASN H ND2  1 
ATOM   3800 H H    . ASN B 2 160 ? -10.298 32.827 37.811  1.00 22.45 ? 160 ASN H H    1 
ATOM   3801 H HA   . ASN B 2 160 ? -9.886  33.899 39.591  1.00 23.67 ? 160 ASN H HA   1 
ATOM   3802 H HB2  . ASN B 2 160 ? -8.998  31.334 40.340  1.00 25.47 ? 160 ASN H HB2  1 
ATOM   3803 H HB3  . ASN B 2 160 ? -9.231  32.503 41.391  1.00 25.47 ? 160 ASN H HB3  1 
ATOM   3804 H HD21 . ASN B 2 160 ? -12.101 30.452 41.447  1.00 26.01 ? 160 ASN H HD21 1 
ATOM   3805 H HD22 . ASN B 2 160 ? -10.658 30.262 41.766  1.00 26.01 ? 160 ASN H HD22 1 
ATOM   3806 N N    . SER B 2 161 ? -7.517  34.534 38.530  1.00 19.41 ? 161 SER H N    1 
ATOM   3807 C CA   . SER B 2 161 ? -6.258  35.267 38.460  1.00 22.32 ? 161 SER H CA   1 
ATOM   3808 C C    . SER B 2 161 ? -5.060  34.349 38.431  1.00 18.89 ? 161 SER H C    1 
ATOM   3809 O O    . SER B 2 161 ? -3.935  34.804 38.626  1.00 19.27 ? 161 SER H O    1 
ATOM   3810 C CB   . SER B 2 161 ? -6.099  36.274 39.607  1.00 25.73 ? 161 SER H CB   1 
ATOM   3811 O OG   . SER B 2 161 ? -7.264  37.071 39.721  1.00 26.11 ? 161 SER H OG   1 
ATOM   3812 H H    . SER B 2 161 ? -8.025  34.687 37.854  1.00 23.35 ? 161 SER H H    1 
ATOM   3813 H HA   . SER B 2 161 ? -6.276  35.769 37.631  1.00 26.84 ? 161 SER H HA   1 
ATOM   3814 H HB2  . SER B 2 161 ? -5.960  35.792 40.437  1.00 30.94 ? 161 SER H HB2  1 
ATOM   3815 H HB3  . SER B 2 161 ? -5.338  36.847 39.424  1.00 30.94 ? 161 SER H HB3  1 
ATOM   3816 H HG   . SER B 2 161 ? -7.151  37.662 40.308  1.00 31.39 ? 161 SER H HG   1 
ATOM   3817 N N    . GLY B 2 162 ? -5.260  33.084 38.126  1.00 18.93 ? 162 GLY H N    1 
ATOM   3818 C CA   . GLY B 2 162 ? -4.170  32.144 37.982  1.00 21.73 ? 162 GLY H CA   1 
ATOM   3819 C C    . GLY B 2 162 ? -4.161  31.086 39.056  1.00 25.06 ? 162 GLY H C    1 
ATOM   3820 O O    . GLY B 2 162 ? -3.391  30.121 38.950  1.00 23.67 ? 162 GLY H O    1 
ATOM   3821 H H    . GLY B 2 162 ? -6.037  32.738 37.994  1.00 22.77 ? 162 GLY H H    1 
ATOM   3822 H HA2  . GLY B 2 162 ? -4.242  31.702 37.122  1.00 26.14 ? 162 GLY H HA2  1 
ATOM   3823 H HA3  . GLY B 2 162 ? -3.328  32.624 38.022  1.00 26.14 ? 162 GLY H HA3  1 
ATOM   3824 N N    . ALA B 2 163 ? -5.005  31.249 40.088  1.00 22.07 ? 163 ALA H N    1 
ATOM   3825 C CA   . ALA B 2 163 ? -5.012  30.348 41.243  1.00 22.42 ? 163 ALA H CA   1 
ATOM   3826 C C    . ALA B 2 163 ? -5.711  29.023 40.936  1.00 23.55 ? 163 ALA H C    1 
ATOM   3827 O O    . ALA B 2 163 ? -5.494  28.022 41.632  1.00 25.13 ? 163 ALA H O    1 
ATOM   3828 C CB   . ALA B 2 163 ? -5.711  31.027 42.436  1.00 25.33 ? 163 ALA H CB   1 
ATOM   3829 H H    . ALA B 2 163 ? -5.588  31.879 40.141  1.00 26.54 ? 163 ALA H H    1 
ATOM   3830 H HA   . ALA B 2 163 ? -4.092  30.160 41.484  1.00 26.97 ? 163 ALA H HA   1 
ATOM   3831 H HB1  . ALA B 2 163 ? -6.569  30.600 42.585  1.00 30.46 ? 163 ALA H HB1  1 
ATOM   3832 H HB2  . ALA B 2 163 ? -5.154  30.933 43.224  1.00 30.46 ? 163 ALA H HB2  1 
ATOM   3833 H HB3  . ALA B 2 163 ? -5.841  31.967 42.233  1.00 30.46 ? 163 ALA H HB3  1 
ATOM   3834 N N    . LEU B 2 164 ? -6.613  29.024 39.961  1.00 26.23 ? 164 LEU H N    1 
ATOM   3835 C CA   . LEU B 2 164 ? -7.294  27.821 39.498  1.00 27.41 ? 164 LEU H CA   1 
ATOM   3836 C C    . LEU B 2 164 ? -6.626  27.349 38.210  1.00 30.21 ? 164 LEU H C    1 
ATOM   3837 O O    . LEU B 2 164 ? -6.714  28.029 37.181  1.00 31.09 ? 164 LEU H O    1 
ATOM   3838 C CB   . LEU B 2 164 ? -8.774  28.089 39.236  1.00 21.66 ? 164 LEU H CB   1 
ATOM   3839 C CG   . LEU B 2 164 ? -9.643  26.867 38.915  1.00 24.93 ? 164 LEU H CG   1 
ATOM   3840 C CD1  . LEU B 2 164 ? -9.544  25.744 39.973  1.00 27.87 ? 164 LEU H CD1  1 
ATOM   3841 C CD2  . LEU B 2 164 ? -11.049 27.293 38.725  1.00 20.17 ? 164 LEU H CD2  1 
ATOM   3842 H H    . LEU B 2 164 ? -6.854  29.733 39.538  1.00 31.54 ? 164 LEU H H    1 
ATOM   3843 H HA   . LEU B 2 164 ? -7.209  27.137 40.181  1.00 32.95 ? 164 LEU H HA   1 
ATOM   3844 H HB2  . LEU B 2 164 ? -9.149  28.506 40.027  1.00 26.05 ? 164 LEU H HB2  1 
ATOM   3845 H HB3  . LEU B 2 164 ? -8.841  28.693 38.479  1.00 26.05 ? 164 LEU H HB3  1 
ATOM   3846 H HG   . LEU B 2 164 ? -9.308  26.475 38.094  1.00 29.97 ? 164 LEU H HG   1 
ATOM   3847 H HD11 . LEU B 2 164 ? -10.176 25.043 39.749  1.00 33.51 ? 164 LEU H HD11 1 
ATOM   3848 H HD12 . LEU B 2 164 ? -8.642  25.389 39.973  1.00 33.51 ? 164 LEU H HD12 1 
ATOM   3849 H HD13 . LEU B 2 164 ? -9.754  26.113 40.846  1.00 33.51 ? 164 LEU H HD13 1 
ATOM   3850 H HD21 . LEU B 2 164 ? -11.593 26.512 38.541  1.00 24.27 ? 164 LEU H HD21 1 
ATOM   3851 H HD22 . LEU B 2 164 ? -11.359 27.729 39.535  1.00 24.27 ? 164 LEU H HD22 1 
ATOM   3852 H HD23 . LEU B 2 164 ? -11.093 27.911 37.979  1.00 24.27 ? 164 LEU H HD23 1 
ATOM   3853 N N    . THR B 2 165 ? -5.958  26.190 38.268  1.00 26.06 ? 165 THR H N    1 
ATOM   3854 C CA   . THR B 2 165 ? -5.278  25.609 37.114  1.00 31.64 ? 165 THR H CA   1 
ATOM   3855 C C    . THR B 2 165 ? -5.691  24.158 36.935  1.00 30.52 ? 165 THR H C    1 
ATOM   3856 O O    . THR B 2 165 ? -5.768  23.662 35.811  1.00 24.62 ? 165 THR H O    1 
ATOM   3857 C CB   . THR B 2 165 ? -3.761  25.721 37.302  1.00 27.22 ? 165 THR H CB   1 
ATOM   3858 O OG1  . THR B 2 165 ? -3.400  25.172 38.579  1.00 26.58 ? 165 THR H OG1  1 
ATOM   3859 C CG2  . THR B 2 165 ? -3.366  27.157 37.216  1.00 26.44 ? 165 THR H CG2  1 
ATOM   3860 H H    . THR B 2 165 ? -5.884  25.715 38.980  1.00 31.33 ? 165 THR H H    1 
ATOM   3861 H HA   . THR B 2 165 ? -5.522  26.089 36.307  1.00 38.03 ? 165 THR H HA   1 
ATOM   3862 H HB   . THR B 2 165 ? -3.286  25.230 36.614  1.00 32.72 ? 165 THR H HB   1 
ATOM   3863 H HG1  . THR B 2 165 ? -2.673  25.503 38.839  1.00 31.96 ? 165 THR H HG1  1 
ATOM   3864 H HG21 . THR B 2 165 ? -2.404  27.242 37.308  1.00 31.78 ? 165 THR H HG21 1 
ATOM   3865 H HG22 . THR B 2 165 ? -3.634  27.523 36.358  1.00 31.78 ? 165 THR H HG22 1 
ATOM   3866 H HG23 . THR B 2 165 ? -3.796  27.662 37.923  1.00 31.78 ? 165 THR H HG23 1 
ATOM   3867 N N    . SER B 2 166 ? -5.915  23.452 38.039  1.00 27.01 ? 166 SER H N    1 
ATOM   3868 C CA   . SER B 2 166 ? -6.294  22.048 37.951  1.00 31.24 ? 166 SER H CA   1 
ATOM   3869 C C    . SER B 2 166 ? -7.596  21.907 37.181  1.00 26.76 ? 166 SER H C    1 
ATOM   3870 O O    . SER B 2 166 ? -8.589  22.561 37.491  1.00 23.54 ? 166 SER H O    1 
ATOM   3871 C CB   . SER B 2 166 ? -6.456  21.431 39.342  1.00 30.23 ? 166 SER H CB   1 
ATOM   3872 O OG   . SER B 2 166 ? -5.210  21.388 40.005  1.00 42.92 ? 166 SER H OG   1 
ATOM   3873 H H    . SER B 2 166 ? -5.855  23.759 38.840  1.00 32.47 ? 166 SER H H    1 
ATOM   3874 H HA   . SER B 2 166 ? -5.590  21.566 37.490  1.00 37.55 ? 166 SER H HA   1 
ATOM   3875 H HB2  . SER B 2 166 ? -7.073  21.971 39.860  1.00 36.34 ? 166 SER H HB2  1 
ATOM   3876 H HB3  . SER B 2 166 ? -6.800  20.529 39.252  1.00 36.34 ? 166 SER H HB3  1 
ATOM   3877 H HG   . SER B 2 166 ? -5.306  21.065 40.775  1.00 51.56 ? 166 SER H HG   1 
ATOM   3878 N N    . GLY B 2 167 ? -7.586  21.056 36.169  1.00 19.70 ? 167 GLY H N    1 
ATOM   3879 C CA   . GLY B 2 167 ? -8.778  20.787 35.406  1.00 20.01 ? 167 GLY H CA   1 
ATOM   3880 C C    . GLY B 2 167 ? -9.145  21.842 34.391  1.00 21.45 ? 167 GLY H C    1 
ATOM   3881 O O    . GLY B 2 167 ? -10.194 21.711 33.754  1.00 20.34 ? 167 GLY H O    1 
ATOM   3882 H H    . GLY B 2 167 ? -6.892  20.620 35.907  1.00 23.70 ? 167 GLY H H    1 
ATOM   3883 H HA2  . GLY B 2 167 ? -8.659  19.950 34.931  1.00 24.07 ? 167 GLY H HA2  1 
ATOM   3884 H HA3  . GLY B 2 167 ? -9.524  20.699 36.020  1.00 24.07 ? 167 GLY H HA3  1 
ATOM   3885 N N    . VAL B 2 168 ? -8.329  22.878 34.218  1.00 19.91 ? 168 VAL H N    1 
ATOM   3886 C CA   . VAL B 2 168 ? -8.612  23.897 33.212  1.00 14.38 ? 168 VAL H CA   1 
ATOM   3887 C C    . VAL B 2 168 ? -8.157  23.394 31.852  1.00 19.12 ? 168 VAL H C    1 
ATOM   3888 O O    . VAL B 2 168 ? -7.053  22.844 31.709  1.00 18.08 ? 168 VAL H O    1 
ATOM   3889 C CB   . VAL B 2 168 ? -7.913  25.223 33.537  1.00 18.33 ? 168 VAL H CB   1 
ATOM   3890 C CG1  . VAL B 2 168 ? -8.044  26.197 32.364  1.00 18.33 ? 168 VAL H CG1  1 
ATOM   3891 C CG2  . VAL B 2 168 ? -8.481  25.810 34.795  1.00 22.10 ? 168 VAL H CG2  1 
ATOM   3892 H H    . VAL B 2 168 ? -7.609  23.012 34.669  1.00 23.95 ? 168 VAL H H    1 
ATOM   3893 H HA   . VAL B 2 168 ? -9.570  24.050 33.204  1.00 17.32 ? 168 VAL H HA   1 
ATOM   3894 H HB   . VAL B 2 168 ? -6.968  25.062 33.683  1.00 22.06 ? 168 VAL H HB   1 
ATOM   3895 H HG11 . VAL B 2 168 ? -7.870  27.098 32.679  1.00 22.05 ? 168 VAL H HG11 1 
ATOM   3896 H HG12 . VAL B 2 168 ? -7.400  25.956 31.679  1.00 22.05 ? 168 VAL H HG12 1 
ATOM   3897 H HG13 . VAL B 2 168 ? -8.944  26.141 32.006  1.00 22.05 ? 168 VAL H HG13 1 
ATOM   3898 H HG21 . VAL B 2 168 ? -8.021  26.641 34.991  1.00 26.58 ? 168 VAL H HG21 1 
ATOM   3899 H HG22 . VAL B 2 168 ? -9.427  25.978 34.666  1.00 26.58 ? 168 VAL H HG22 1 
ATOM   3900 H HG23 . VAL B 2 168 ? -8.353  25.181 35.522  1.00 26.58 ? 168 VAL H HG23 1 
ATOM   3901 N N    . HIS B 2 169 ? -8.987  23.615 30.846  1.00 17.12 ? 169 HIS H N    1 
ATOM   3902 C CA   . HIS B 2 169 ? -8.636  23.427 29.447  1.00 18.73 ? 169 HIS H CA   1 
ATOM   3903 C C    . HIS B 2 169 ? -9.068  24.666 28.700  1.00 17.83 ? 169 HIS H C    1 
ATOM   3904 O O    . HIS B 2 169 ? -10.265 24.943 28.617  1.00 17.88 ? 169 HIS H O    1 
ATOM   3905 C CB   . HIS B 2 169 ? -9.318  22.200 28.825  1.00 18.84 ? 169 HIS H CB   1 
ATOM   3906 C CG   . HIS B 2 169 ? -8.959  20.906 29.475  1.00 18.24 ? 169 HIS H CG   1 
ATOM   3907 N ND1  . HIS B 2 169 ? -7.687  20.389 29.403  1.00 20.16 ? 169 HIS H ND1  1 
ATOM   3908 C CD2  . HIS B 2 169 ? -9.710  19.974 30.109  1.00 19.03 ? 169 HIS H CD2  1 
ATOM   3909 C CE1  . HIS B 2 169 ? -7.652  19.227 30.027  1.00 21.94 ? 169 HIS H CE1  1 
ATOM   3910 N NE2  . HIS B 2 169 ? -8.870  18.947 30.457  1.00 19.68 ? 169 HIS H NE2  1 
ATOM   3911 H H    . HIS B 2 169 ? -9.797  23.886 30.952  1.00 20.61 ? 169 HIS H H    1 
ATOM   3912 H HA   . HIS B 2 169 ? -7.677  23.302 29.379  1.00 22.53 ? 169 HIS H HA   1 
ATOM   3913 H HB2  . HIS B 2 169 ? -10.279 22.309 28.898  1.00 22.67 ? 169 HIS H HB2  1 
ATOM   3914 H HB3  . HIS B 2 169 ? -9.060  22.141 27.892  1.00 22.67 ? 169 HIS H HB3  1 
ATOM   3915 H HD2  . HIS B 2 169 ? -10.624 20.021 30.277  1.00 22.90 ? 169 HIS H HD2  1 
ATOM   3916 H HE1  . HIS B 2 169 ? -6.898  18.695 30.143  1.00 26.39 ? 169 HIS H HE1  1 
ATOM   3917 H HE2  . HIS B 2 169 ? -9.098  18.237 30.885  1.00 23.67 ? 169 HIS H HE2  1 
ATOM   3918 N N    . THR B 2 170 ? -8.103  25.358 28.113  1.00 16.94 ? 170 THR H N    1 
ATOM   3919 C CA   . THR B 2 170 ? -8.361  26.461 27.200  1.00 16.92 ? 170 THR H CA   1 
ATOM   3920 C C    . THR B 2 170 ? -8.048  25.990 25.787  1.00 18.10 ? 170 THR H C    1 
ATOM   3921 O O    . THR B 2 170 ? -6.888  25.676 25.478  1.00 18.64 ? 170 THR H O    1 
ATOM   3922 C CB   . THR B 2 170 ? -7.552  27.693 27.596  1.00 17.63 ? 170 THR H CB   1 
ATOM   3923 O OG1  . THR B 2 170 ? -7.919  28.072 28.938  1.00 18.37 ? 170 THR H OG1  1 
ATOM   3924 C CG2  . THR B 2 170 ? -7.813  28.795 26.597  1.00 20.31 ? 170 THR H CG2  1 
ATOM   3925 H H    . THR B 2 170 ? -7.265  25.202 28.231  1.00 20.39 ? 170 THR H H    1 
ATOM   3926 H HA   . THR B 2 170 ? -9.300  26.706 27.229  1.00 20.37 ? 170 THR H HA   1 
ATOM   3927 H HB   . THR B 2 170 ? -6.597  27.522 27.590  1.00 21.21 ? 170 THR H HB   1 
ATOM   3928 H HG1  . THR B 2 170 ? -7.490  28.756 29.171  1.00 22.11 ? 170 THR H HG1  1 
ATOM   3929 H HG21 . THR B 2 170 ? -7.406  29.622 26.901  1.00 24.44 ? 170 THR H HG21 1 
ATOM   3930 H HG22 . THR B 2 170 ? -7.436  28.558 25.735  1.00 24.44 ? 170 THR H HG22 1 
ATOM   3931 H HG23 . THR B 2 170 ? -8.768  28.933 26.496  1.00 24.44 ? 170 THR H HG23 1 
ATOM   3932 N N    . PHE B 2 171 ? -9.101  25.902 24.966  1.00 13.64 ? 171 PHE H N    1 
ATOM   3933 C CA   . PHE B 2 171 ? -9.022  25.342 23.619  1.00 14.37 ? 171 PHE H CA   1 
ATOM   3934 C C    . PHE B 2 171 ? -8.305  26.286 22.651  1.00 18.72 ? 171 PHE H C    1 
ATOM   3935 O O    . PHE B 2 171 ? -8.310  27.489 22.825  1.00 16.66 ? 171 PHE H O    1 
ATOM   3936 C CB   . PHE B 2 171 ? -10.426 24.992 23.081  1.00 13.65 ? 171 PHE H CB   1 
ATOM   3937 C CG   . PHE B 2 171 ? -11.073 23.924 23.878  1.00 14.94 ? 171 PHE H CG   1 
ATOM   3938 C CD1  . PHE B 2 171 ? -10.781 22.628 23.590  1.00 15.18 ? 171 PHE H CD1  1 
ATOM   3939 C CD2  . PHE B 2 171 ? -11.954 24.192 24.914  1.00 16.99 ? 171 PHE H CD2  1 
ATOM   3940 C CE1  . PHE B 2 171 ? -11.262 21.615 24.344  1.00 14.98 ? 171 PHE H CE1  1 
ATOM   3941 C CE2  . PHE B 2 171 ? -12.482 23.132 25.663  1.00 16.20 ? 171 PHE H CE2  1 
ATOM   3942 C CZ   . PHE B 2 171 ? -12.122 21.852 25.351  1.00 15.84 ? 171 PHE H CZ   1 
ATOM   3943 H H    . PHE B 2 171 ? -9.892  26.168 25.173  1.00 16.43 ? 171 PHE H H    1 
ATOM   3944 H HA   . PHE B 2 171 ? -8.502  24.523 23.659  1.00 17.31 ? 171 PHE H HA   1 
ATOM   3945 H HB2  . PHE B 2 171 ? -10.988 25.782 23.119  1.00 16.44 ? 171 PHE H HB2  1 
ATOM   3946 H HB3  . PHE B 2 171 ? -10.349 24.684 22.165  1.00 16.44 ? 171 PHE H HB3  1 
ATOM   3947 H HD1  . PHE B 2 171 ? -10.238 22.435 22.860  1.00 18.27 ? 171 PHE H HD1  1 
ATOM   3948 H HD2  . PHE B 2 171 ? -12.193 25.069 25.110  1.00 20.45 ? 171 PHE H HD2  1 
ATOM   3949 H HE1  . PHE B 2 171 ? -10.996 20.742 24.163  1.00 18.04 ? 171 PHE H HE1  1 
ATOM   3950 H HE2  . PHE B 2 171 ? -13.070 23.298 26.365  1.00 19.50 ? 171 PHE H HE2  1 
ATOM   3951 H HZ   . PHE B 2 171 ? -12.472 21.141 25.837  1.00 19.07 ? 171 PHE H HZ   1 
ATOM   3952 N N    . PRO B 2 172 ? -7.614  25.738 21.652  1.00 15.82 ? 172 PRO H N    1 
ATOM   3953 C CA   . PRO B 2 172 ? -7.107  26.559 20.551  1.00 19.58 ? 172 PRO H CA   1 
ATOM   3954 C C    . PRO B 2 172 ? -8.256  27.324 19.900  1.00 17.39 ? 172 PRO H C    1 
ATOM   3955 O O    . PRO B 2 172 ? -9.384  26.829 19.822  1.00 15.53 ? 172 PRO H O    1 
ATOM   3956 C CB   . PRO B 2 172 ? -6.527  25.521 19.577  1.00 22.08 ? 172 PRO H CB   1 
ATOM   3957 C CG   . PRO B 2 172 ? -6.326  24.286 20.356  1.00 24.63 ? 172 PRO H CG   1 
ATOM   3958 C CD   . PRO B 2 172 ? -7.468  24.305 21.371  1.00 16.99 ? 172 PRO H CD   1 
ATOM   3959 H HA   . PRO B 2 172 ? -6.410  27.165 20.847  1.00 23.55 ? 172 PRO H HA   1 
ATOM   3960 H HB2  . PRO B 2 172 ? -7.154  25.370 18.852  1.00 26.55 ? 172 PRO H HB2  1 
ATOM   3961 H HB3  . PRO B 2 172 ? -5.683  25.844 19.224  1.00 26.55 ? 172 PRO H HB3  1 
ATOM   3962 H HG2  . PRO B 2 172 ? -6.384  23.511 19.776  1.00 29.62 ? 172 PRO H HG2  1 
ATOM   3963 H HG3  . PRO B 2 172 ? -5.463  24.306 20.799  1.00 29.62 ? 172 PRO H HG3  1 
ATOM   3964 H HD2  . PRO B 2 172 ? -8.281  23.940 20.988  1.00 20.45 ? 172 PRO H HD2  1 
ATOM   3965 H HD3  . PRO B 2 172 ? -7.230  23.814 22.173  1.00 20.45 ? 172 PRO H HD3  1 
ATOM   3966 N N    . ALA B 2 173 ? -7.960  28.520 19.404  1.00 19.76 ? 173 ALA H N    1 
ATOM   3967 C CA   . ALA B 2 173 ? -8.967  29.295 18.681  1.00 18.18 ? 173 ALA H CA   1 
ATOM   3968 C C    . ALA B 2 173 ? -9.383  28.608 17.387  1.00 20.46 ? 173 ALA H C    1 
ATOM   3969 O O    . ALA B 2 173 ? -8.619  27.838 16.781  1.00 20.15 ? 173 ALA H O    1 
ATOM   3970 C CB   . ALA B 2 173 ? -8.442  30.700 18.356  1.00 21.73 ? 173 ALA H CB   1 
ATOM   3971 H H    . ALA B 2 173 ? -7.193  28.903 19.471  1.00 23.78 ? 173 ALA H H    1 
ATOM   3972 H HA   . ALA B 2 173 ? -9.750  29.377 19.248  1.00 21.87 ? 173 ALA H HA   1 
ATOM   3973 H HB1  . ALA B 2 173 ? -9.138  31.200 17.903  1.00 26.14 ? 173 ALA H HB1  1 
ATOM   3974 H HB2  . ALA B 2 173 ? -8.199  31.146 19.183  1.00 26.14 ? 173 ALA H HB2  1 
ATOM   3975 H HB3  . ALA B 2 173 ? -7.664  30.621 17.782  1.00 26.14 ? 173 ALA H HB3  1 
ATOM   3976 N N    . VAL B 2 174 ? -10.621 28.897 16.962  1.00 18.78 ? 174 VAL H N    1 
ATOM   3977 C CA   . VAL B 2 174 ? -11.110 28.552 15.631  1.00 20.17 ? 174 VAL H CA   1 
ATOM   3978 C C    . VAL B 2 174 ? -11.361 29.849 14.885  1.00 24.12 ? 174 VAL H C    1 
ATOM   3979 O O    . VAL B 2 174 ? -11.842 30.823 15.475  1.00 22.43 ? 174 VAL H O    1 
ATOM   3980 C CB   . VAL B 2 174 ? -12.404 27.706 15.646  1.00 26.49 ? 174 VAL H CB   1 
ATOM   3981 C CG1  . VAL B 2 174 ? -12.179 26.337 16.319  1.00 25.20 ? 174 VAL H CG1  1 
ATOM   3982 C CG2  . VAL B 2 174 ? -13.554 28.456 16.282  1.00 28.40 ? 174 VAL H CG2  1 
ATOM   3983 H H    . VAL B 2 174 ? -11.206 29.304 17.444  1.00 22.59 ? 174 VAL H H    1 
ATOM   3984 H HA   . VAL B 2 174 ? -10.426 28.025 15.189  1.00 24.26 ? 174 VAL H HA   1 
ATOM   3985 H HB   . VAL B 2 174 ? -12.652 27.533 14.724  1.00 31.85 ? 174 VAL H HB   1 
ATOM   3986 H HG11 . VAL B 2 174 ? -13.006 25.832 16.293  1.00 30.30 ? 174 VAL H HG11 1 
ATOM   3987 H HG12 . VAL B 2 174 ? -11.484 25.860 15.840  1.00 30.30 ? 174 VAL H HG12 1 
ATOM   3988 H HG13 . VAL B 2 174 ? -11.907 26.479 17.240  1.00 30.30 ? 174 VAL H HG13 1 
ATOM   3989 H HG21 . VAL B 2 174 ? -14.248 27.823 16.524  1.00 34.14 ? 174 VAL H HG21 1 
ATOM   3990 H HG22 . VAL B 2 174 ? -13.232 28.913 17.075  1.00 34.14 ? 174 VAL H HG22 1 
ATOM   3991 H HG23 . VAL B 2 174 ? -13.901 29.100 15.646  1.00 34.14 ? 174 VAL H HG23 1 
ATOM   3992 N N    . LEU B 2 175 ? -11.022 29.875 13.594  1.00 20.89 ? 175 LEU H N    1 
ATOM   3993 C CA   . LEU B 2 175 ? -11.362 31.015 12.762  1.00 19.89 ? 175 LEU H CA   1 
ATOM   3994 C C    . LEU B 2 175 ? -12.782 30.840 12.248  1.00 23.33 ? 175 LEU H C    1 
ATOM   3995 O O    . LEU B 2 175 ? -13.089 29.856 11.564  1.00 25.66 ? 175 LEU H O    1 
ATOM   3996 C CB   . LEU B 2 175 ? -10.376 31.133 11.615  1.00 21.06 ? 175 LEU H CB   1 
ATOM   3997 C CG   . LEU B 2 175 ? -10.501 32.341 10.701  1.00 22.98 ? 175 LEU H CG   1 
ATOM   3998 C CD1  . LEU B 2 175 ? -10.422 33.674 11.406  1.00 20.76 ? 175 LEU H CD1  1 
ATOM   3999 C CD2  . LEU B 2 175 ? -9.358  32.226 9.667   1.00 21.79 ? 175 LEU H CD2  1 
ATOM   4000 H H    . LEU B 2 175 ? -10.598 29.248 13.187  1.00 25.13 ? 175 LEU H H    1 
ATOM   4001 H HA   . LEU B 2 175 ? -11.319 31.834 13.280  1.00 23.93 ? 175 LEU H HA   1 
ATOM   4002 H HB2  . LEU B 2 175 ? -9.483  31.159 11.993  1.00 25.34 ? 175 LEU H HB2  1 
ATOM   4003 H HB3  . LEU B 2 175 ? -10.476 30.347 11.055  1.00 25.34 ? 175 LEU H HB3  1 
ATOM   4004 H HG   . LEU B 2 175 ? -11.381 32.335 10.293  1.00 27.64 ? 175 LEU H HG   1 
ATOM   4005 H HD11 . LEU B 2 175 ? -10.551 34.383 10.756  1.00 24.97 ? 175 LEU H HD11 1 
ATOM   4006 H HD12 . LEU B 2 175 ? -11.117 33.715 12.082  1.00 24.97 ? 175 LEU H HD12 1 
ATOM   4007 H HD13 . LEU B 2 175 ? -9.550  33.760 11.821  1.00 24.97 ? 175 LEU H HD13 1 
ATOM   4008 H HD21 . LEU B 2 175 ? -9.376  33.005 9.088   1.00 26.20 ? 175 LEU H HD21 1 
ATOM   4009 H HD22 . LEU B 2 175 ? -8.510  32.183 10.137  1.00 26.20 ? 175 LEU H HD22 1 
ATOM   4010 H HD23 . LEU B 2 175 ? -9.487  31.421 9.142   1.00 26.20 ? 175 LEU H HD23 1 
ATOM   4011 N N    . GLN B 2 176 ? -13.657 31.771 12.605  1.00 25.19 ? 176 GLN H N    1 
ATOM   4012 C CA   . GLN B 2 176 ? -15.026 31.636 12.193  1.00 27.51 ? 176 GLN H CA   1 
ATOM   4013 C C    . GLN B 2 176 ? -15.187 32.133 10.752  1.00 29.08 ? 176 GLN H C    1 
ATOM   4014 O O    . GLN B 2 176 ? -14.307 32.805 10.182  1.00 25.23 ? 176 GLN H O    1 
ATOM   4015 C CB   . GLN B 2 176 ? -15.977 32.383 13.127  1.00 23.59 ? 176 GLN H CB   1 
ATOM   4016 C CG   . GLN B 2 176 ? -16.204 31.777 14.491  1.00 26.48 ? 176 GLN H CG   1 
ATOM   4017 C CD   . GLN B 2 176 ? -16.579 32.789 15.552  1.00 22.61 ? 176 GLN H CD   1 
ATOM   4018 O OE1  . GLN B 2 176 ? -17.487 32.482 16.368  1.00 29.72 ? 176 GLN H OE1  1 
ATOM   4019 N NE2  . GLN B 2 176 ? -15.870 33.936 15.635  1.00 25.18 ? 176 GLN H NE2  1 
ATOM   4020 H H    . GLN B 2 176 ? -13.478 32.469 13.074  1.00 30.29 ? 176 GLN H H    1 
ATOM   4021 H HA   . GLN B 2 176 ? -15.273 30.699 12.233  1.00 33.07 ? 176 GLN H HA   1 
ATOM   4022 H HB2  . GLN B 2 176 ? -15.620 33.274 13.269  1.00 28.37 ? 176 GLN H HB2  1 
ATOM   4023 H HB3  . GLN B 2 176 ? -16.843 32.438 12.694  1.00 28.37 ? 176 GLN H HB3  1 
ATOM   4024 H HG2  . GLN B 2 176 ? -16.926 31.131 14.429  1.00 31.83 ? 176 GLN H HG2  1 
ATOM   4025 H HG3  . GLN B 2 176 ? -15.389 31.336 14.777  1.00 31.83 ? 176 GLN H HG3  1 
ATOM   4026 H HE21 . GLN B 2 176 ? -15.220 34.080 15.090  1.00 30.28 ? 176 GLN H HE21 1 
ATOM   4027 H HE22 . GLN B 2 176 ? -16.069 34.523 16.232  1.00 30.28 ? 176 GLN H HE22 1 
ATOM   4028 N N    . SER B 2 177 ? -16.351 31.804 10.171  1.00 34.24 ? 177 SER H N    1 
ATOM   4029 C CA   . SER B 2 177 ? -16.686 32.296 8.836   1.00 37.77 ? 177 SER H CA   1 
ATOM   4030 C C    . SER B 2 177 ? -16.588 33.819 8.749   1.00 35.45 ? 177 SER H C    1 
ATOM   4031 O O    . SER B 2 177 ? -16.262 34.366 7.687   1.00 38.94 ? 177 SER H O    1 
ATOM   4032 C CB   . SER B 2 177 ? -18.095 31.821 8.449   1.00 40.86 ? 177 SER H CB   1 
ATOM   4033 O OG   . SER B 2 177 ? -19.030 32.134 9.473   1.00 48.17 ? 177 SER H OG   1 
ATOM   4034 H H    . SER B 2 177 ? -16.953 31.304 10.528  1.00 41.15 ? 177 SER H H    1 
ATOM   4035 H HA   . SER B 2 177 ? -16.058 31.928 8.195   1.00 45.39 ? 177 SER H HA   1 
ATOM   4036 H HB2  . SER B 2 177 ? -18.364 32.264 7.629   1.00 49.09 ? 177 SER H HB2  1 
ATOM   4037 H HB3  . SER B 2 177 ? -18.080 30.860 8.317   1.00 49.09 ? 177 SER H HB3  1 
ATOM   4038 H HG   . SER B 2 177 ? -19.799 31.883 9.247   1.00 57.87 ? 177 SER H HG   1 
ATOM   4039 N N    . SER B 2 178 ? -16.863 34.521 9.850   1.00 30.69 ? 178 SER H N    1 
ATOM   4040 C CA   . SER B 2 178 ? -16.818 35.982 9.876   1.00 30.57 ? 178 SER H CA   1 
ATOM   4041 C C    . SER B 2 178 ? -15.414 36.551 9.760   1.00 31.36 ? 178 SER H C    1 
ATOM   4042 O O    . SER B 2 178 ? -15.260 37.771 9.640   1.00 32.22 ? 178 SER H O    1 
ATOM   4043 C CB   . SER B 2 178 ? -17.419 36.500 11.191  1.00 34.19 ? 178 SER H CB   1 
ATOM   4044 O OG   . SER B 2 178 ? -16.671 35.974 12.281  1.00 36.39 ? 178 SER H OG   1 
ATOM   4045 H H    . SER B 2 178 ? -17.080 34.170 10.604  1.00 36.89 ? 178 SER H H    1 
ATOM   4046 H HA   . SER B 2 178 ? -17.343 36.300 9.125   1.00 36.75 ? 178 SER H HA   1 
ATOM   4047 H HB2  . SER B 2 178 ? -17.376 37.469 11.206  1.00 41.09 ? 178 SER H HB2  1 
ATOM   4048 H HB3  . SER B 2 178 ? -18.341 36.208 11.261  1.00 41.09 ? 178 SER H HB3  1 
ATOM   4049 H HG   . SER B 2 178 ? -17.037 36.183 13.008  1.00 43.72 ? 178 SER H HG   1 
ATOM   4050 N N    . GLY B 2 179 ? -14.383 35.729 9.860   1.00 31.08 ? 179 GLY H N    1 
ATOM   4051 C CA   . GLY B 2 179 ? -13.049 36.263 9.935   1.00 24.93 ? 179 GLY H CA   1 
ATOM   4052 C C    . GLY B 2 179 ? -12.587 36.565 11.335  1.00 22.06 ? 179 GLY H C    1 
ATOM   4053 O O    . GLY B 2 179 ? -11.431 36.955 11.520  1.00 21.49 ? 179 GLY H O    1 
ATOM   4054 H H    . GLY B 2 179 ? -14.435 34.871 9.885   1.00 37.35 ? 179 GLY H H    1 
ATOM   4055 H HA2  . GLY B 2 179 ? -12.432 35.623 9.548   1.00 29.98 ? 179 GLY H HA2  1 
ATOM   4056 H HA3  . GLY B 2 179 ? -13.012 37.087 9.424   1.00 29.98 ? 179 GLY H HA3  1 
ATOM   4057 N N    . LEU B 2 180 ? -13.443 36.379 12.323  1.00 24.21 ? 180 LEU H N    1 
ATOM   4058 C CA   . LEU B 2 180 ? -13.078 36.591 13.707  1.00 21.74 ? 180 LEU H CA   1 
ATOM   4059 C C    . LEU B 2 180 ? -12.834 35.254 14.377  1.00 18.60 ? 180 LEU H C    1 
ATOM   4060 O O    . LEU B 2 180 ? -13.415 34.238 13.988  1.00 18.76 ? 180 LEU H O    1 
ATOM   4061 C CB   . LEU B 2 180 ? -14.184 37.335 14.442  1.00 23.18 ? 180 LEU H CB   1 
ATOM   4062 C CG   . LEU B 2 180 ? -14.591 38.662 13.818  1.00 25.48 ? 180 LEU H CG   1 
ATOM   4063 C CD1  . LEU B 2 180 ? -15.862 39.174 14.566  1.00 28.51 ? 180 LEU H CD1  1 
ATOM   4064 C CD2  . LEU B 2 180 ? -13.507 39.674 13.903  1.00 22.40 ? 180 LEU H CD2  1 
ATOM   4065 H H    . LEU B 2 180 ? -14.258 36.126 12.214  1.00 29.12 ? 180 LEU H H    1 
ATOM   4066 H HA   . LEU B 2 180 ? -12.268 37.121 13.759  1.00 26.15 ? 180 LEU H HA   1 
ATOM   4067 H HB2  . LEU B 2 180 ? -14.972 36.769 14.463  1.00 27.87 ? 180 LEU H HB2  1 
ATOM   4068 H HB3  . LEU B 2 180 ? -13.883 37.518 15.345  1.00 27.87 ? 180 LEU H HB3  1 
ATOM   4069 H HG   . LEU B 2 180 ? -14.774 38.534 12.874  1.00 30.64 ? 180 LEU H HG   1 
ATOM   4070 H HD11 . LEU B 2 180 ? -16.144 40.013 14.171  1.00 34.27 ? 180 LEU H HD11 1 
ATOM   4071 H HD12 . LEU B 2 180 ? -16.567 38.513 14.479  1.00 34.27 ? 180 LEU H HD12 1 
ATOM   4072 H HD13 . LEU B 2 180 ? -15.646 39.305 15.503  1.00 34.27 ? 180 LEU H HD13 1 
ATOM   4073 H HD21 . LEU B 2 180 ? -13.820 40.505 13.512  1.00 26.94 ? 180 LEU H HD21 1 
ATOM   4074 H HD22 . LEU B 2 180 ? -13.277 39.813 14.835  1.00 26.94 ? 180 LEU H HD22 1 
ATOM   4075 H HD23 . LEU B 2 180 ? -12.733 39.350 13.416  1.00 26.94 ? 180 LEU H HD23 1 
ATOM   4076 N N    . TYR B 2 181 ? -11.988 35.267 15.394  1.00 19.04 ? 181 TYR H N    1 
ATOM   4077 C CA   . TYR B 2 181 ? -11.675 34.056 16.124  1.00 19.43 ? 181 TYR H CA   1 
ATOM   4078 C C    . TYR B 2 181 ? -12.633 33.882 17.304  1.00 24.37 ? 181 TYR H C    1 
ATOM   4079 O O    . TYR B 2 181 ? -13.255 34.837 17.794  1.00 20.35 ? 181 TYR H O    1 
ATOM   4080 C CB   . TYR B 2 181 ? -10.239 34.118 16.593  1.00 17.33 ? 181 TYR H CB   1 
ATOM   4081 C CG   . TYR B 2 181 ? -9.219  34.101 15.484  1.00 21.34 ? 181 TYR H CG   1 
ATOM   4082 C CD1  . TYR B 2 181 ? -8.788  32.909 14.936  1.00 21.80 ? 181 TYR H CD1  1 
ATOM   4083 C CD2  . TYR B 2 181 ? -8.736  35.274 14.960  1.00 23.11 ? 181 TYR H CD2  1 
ATOM   4084 C CE1  . TYR B 2 181 ? -7.857  32.894 13.910  1.00 24.05 ? 181 TYR H CE1  1 
ATOM   4085 C CE2  . TYR B 2 181 ? -7.794  35.269 13.969  1.00 22.86 ? 181 TYR H CE2  1 
ATOM   4086 C CZ   . TYR B 2 181 ? -7.354  34.079 13.444  1.00 26.05 ? 181 TYR H CZ   1 
ATOM   4087 O OH   . TYR B 2 181 ? -6.424  34.100 12.435  1.00 24.78 ? 181 TYR H OH   1 
ATOM   4088 H H    . TYR B 2 181 ? -11.581 35.968 15.680  1.00 22.91 ? 181 TYR H H    1 
ATOM   4089 H HA   . TYR B 2 181 ? -11.779 33.276 15.556  1.00 23.37 ? 181 TYR H HA   1 
ATOM   4090 H HB2  . TYR B 2 181 ? -10.112 34.938 17.096  1.00 20.86 ? 181 TYR H HB2  1 
ATOM   4091 H HB3  . TYR B 2 181 ? -10.066 33.351 17.162  1.00 20.86 ? 181 TYR H HB3  1 
ATOM   4092 H HD1  . TYR B 2 181 ? -9.127  32.106 15.259  1.00 26.23 ? 181 TYR H HD1  1 
ATOM   4093 H HD2  . TYR B 2 181 ? -9.055  36.085 15.284  1.00 27.79 ? 181 TYR H HD2  1 
ATOM   4094 H HE1  . TYR B 2 181 ? -7.576  32.088 13.542  1.00 28.93 ? 181 TYR H HE1  1 
ATOM   4095 H HE2  . TYR B 2 181 ? -7.450  36.072 13.651  1.00 27.49 ? 181 TYR H HE2  1 
ATOM   4096 H HH   . TYR B 2 181 ? -6.201  34.892 12.266  1.00 29.80 ? 181 TYR H HH   1 
ATOM   4097 N N    . SER B 2 182 ? -12.705 32.638 17.769  1.00 20.42 ? 182 SER H N    1 
ATOM   4098 C CA   . SER B 2 182 ? -13.443 32.267 18.961  1.00 19.23 ? 182 SER H CA   1 
ATOM   4099 C C    . SER B 2 182 ? -12.756 31.092 19.647  1.00 19.71 ? 182 SER H C    1 
ATOM   4100 O O    . SER B 2 182 ? -12.180 30.214 19.000  1.00 18.57 ? 182 SER H O    1 
ATOM   4101 C CB   . SER B 2 182 ? -14.885 31.924 18.594  1.00 21.14 ? 182 SER H CB   1 
ATOM   4102 O OG   . SER B 2 182 ? -15.631 31.625 19.743  1.00 27.03 ? 182 SER H OG   1 
ATOM   4103 H H    . SER B 2 182 ? -12.318 31.968 17.395  1.00 24.57 ? 182 SER H H    1 
ATOM   4104 H HA   . SER B 2 182 ? -13.444 32.997 19.600  1.00 23.14 ? 182 SER H HA   1 
ATOM   4105 H HB2  . SER B 2 182 ? -15.287 32.684 18.145  1.00 25.43 ? 182 SER H HB2  1 
ATOM   4106 H HB3  . SER B 2 182 ? -14.887 31.152 18.006  1.00 25.43 ? 182 SER H HB3  1 
ATOM   4107 H HG   . SER B 2 182 ? -15.540 32.237 20.312  1.00 32.49 ? 182 SER H HG   1 
ATOM   4108 N N    . LEU B 2 183 ? -12.833 31.073 20.973  1.00 19.47 ? 183 LEU H N    1 
ATOM   4109 C CA   . LEU B 2 183 ? -12.410 29.895 21.720  1.00 16.28 ? 183 LEU H CA   1 
ATOM   4110 C C    . LEU B 2 183 ? -13.194 29.856 23.024  1.00 19.97 ? 183 LEU H C    1 
ATOM   4111 O O    . LEU B 2 183 ? -13.807 30.841 23.429  1.00 17.28 ? 183 LEU H O    1 
ATOM   4112 C CB   . LEU B 2 183 ? -10.888 29.896 21.985  1.00 18.13 ? 183 LEU H CB   1 
ATOM   4113 C CG   . LEU B 2 183 ? -10.361 30.994 22.921  1.00 17.72 ? 183 LEU H CG   1 
ATOM   4114 C CD1  . LEU B 2 183 ? -10.608 30.747 24.430  1.00 16.98 ? 183 LEU H CD1  1 
ATOM   4115 C CD2  . LEU B 2 183 ? -8.862  31.184 22.699  1.00 22.39 ? 183 LEU H CD2  1 
ATOM   4116 H H    . LEU B 2 183 ? -13.123 31.721 21.457  1.00 23.43 ? 183 LEU H H    1 
ATOM   4117 H HA   . LEU B 2 183 ? -12.613 29.092 21.215  1.00 19.60 ? 183 LEU H HA   1 
ATOM   4118 H HB2  . LEU B 2 183 ? -10.651 29.044 22.383  1.00 21.82 ? 183 LEU H HB2  1 
ATOM   4119 H HB3  . LEU B 2 183 ? -10.435 30.004 21.135  1.00 21.82 ? 183 LEU H HB3  1 
ATOM   4120 H HG   . LEU B 2 183 ? -10.862 31.794 22.697  1.00 21.32 ? 183 LEU H HG   1 
ATOM   4121 H HD11 . LEU B 2 183 ? -9.917  31.197 24.941  1.00 20.44 ? 183 LEU H HD11 1 
ATOM   4122 H HD12 . LEU B 2 183 ? -11.479 31.101 24.670  1.00 20.44 ? 183 LEU H HD12 1 
ATOM   4123 H HD13 . LEU B 2 183 ? -10.580 29.793 24.603  1.00 20.44 ? 183 LEU H HD13 1 
ATOM   4124 H HD21 . LEU B 2 183 ? -8.569  31.974 23.178  1.00 26.93 ? 183 LEU H HD21 1 
ATOM   4125 H HD22 . LEU B 2 183 ? -8.392  30.402 23.031  1.00 26.93 ? 183 LEU H HD22 1 
ATOM   4126 H HD23 . LEU B 2 183 ? -8.695  31.291 21.749  1.00 26.93 ? 183 LEU H HD23 1 
ATOM   4127 N N    . SER B 2 184 ? -13.176 28.698 23.665  1.00 15.57 ? 184 SER H N    1 
ATOM   4128 C CA   . SER B 2 184 ? -13.699 28.522 25.018  1.00 16.25 ? 184 SER H CA   1 
ATOM   4129 C C    . SER B 2 184 ? -12.607 28.083 25.970  1.00 17.28 ? 184 SER H C    1 
ATOM   4130 O O    . SER B 2 184 ? -11.645 27.442 25.570  1.00 14.79 ? 184 SER H O    1 
ATOM   4131 C CB   . SER B 2 184 ? -14.828 27.490 25.105  1.00 18.95 ? 184 SER H CB   1 
ATOM   4132 O OG   . SER B 2 184 ? -15.966 27.957 24.396  1.00 24.00 ? 184 SER H OG   1 
ATOM   4133 H H    . SER B 2 184 ? -12.857 27.974 23.330  1.00 18.75 ? 184 SER H H    1 
ATOM   4134 H HA   . SER B 2 184 ? -14.046 29.385 25.293  1.00 19.56 ? 184 SER H HA   1 
ATOM   4135 H HB2  . SER B 2 184 ? -14.528 26.655 24.714  1.00 22.80 ? 184 SER H HB2  1 
ATOM   4136 H HB3  . SER B 2 184 ? -15.066 27.354 26.036  1.00 22.80 ? 184 SER H HB3  1 
ATOM   4137 H HG   . SER B 2 184 ? -16.576 27.380 24.420  1.00 28.86 ? 184 SER H HG   1 
ATOM   4138 N N    . SER B 2 185 ? -12.773 28.454 27.233  1.00 15.04 ? 185 SER H N    1 
ATOM   4139 C CA   . SER B 2 185 ? -11.938 27.947 28.311  1.00 16.32 ? 185 SER H CA   1 
ATOM   4140 C C    . SER B 2 185 ? -12.897 27.305 29.298  1.00 17.32 ? 185 SER H C    1 
ATOM   4141 O O    . SER B 2 185 ? -13.920 27.897 29.640  1.00 15.52 ? 185 SER H O    1 
ATOM   4142 C CB   . SER B 2 185 ? -11.092 29.063 28.918  1.00 16.02 ? 185 SER H CB   1 
ATOM   4143 O OG   . SER B 2 185 ? -10.351 28.583 30.003  1.00 17.43 ? 185 SER H OG   1 
ATOM   4144 H H    . SER B 2 185 ? -13.375 29.010 27.495  1.00 18.11 ? 185 SER H H    1 
ATOM   4145 H HA   . SER B 2 185 ? -11.298 27.279 28.020  1.00 19.65 ? 185 SER H HA   1 
ATOM   4146 H HB2  . SER B 2 185 ? -10.483 29.403 28.244  1.00 19.28 ? 185 SER H HB2  1 
ATOM   4147 H HB3  . SER B 2 185 ? -11.678 29.774 29.225  1.00 19.28 ? 185 SER H HB3  1 
ATOM   4148 H HG   . SER B 2 185 ? -9.864  27.944 29.758  1.00 20.98 ? 185 SER H HG   1 
ATOM   4149 N N    . VAL B 2 186 ? -12.569 26.111 29.741  1.00 16.01 ? 186 VAL H N    1 
ATOM   4150 C CA   . VAL B 2 186 ? -13.426 25.305 30.573  1.00 17.48 ? 186 VAL H CA   1 
ATOM   4151 C C    . VAL B 2 186 ? -12.635 24.776 31.782  1.00 20.78 ? 186 VAL H C    1 
ATOM   4152 O O    . VAL B 2 186 ? -11.395 24.798 31.806  1.00 16.21 ? 186 VAL H O    1 
ATOM   4153 C CB   . VAL B 2 186 ? -13.978 24.174 29.662  1.00 19.22 ? 186 VAL H CB   1 
ATOM   4154 C CG1  . VAL B 2 186 ? -14.758 24.552 28.593  1.00 27.81 ? 186 VAL H CG1  1 
ATOM   4155 C CG2  . VAL B 2 186 ? -12.755 23.174 29.312  1.00 26.83 ? 186 VAL H CG2  1 
ATOM   4156 H H    . VAL B 2 186 ? -11.819 25.729 29.563  1.00 19.27 ? 186 VAL H H    1 
ATOM   4157 H HA   . VAL B 2 186 ? -14.151 25.807 30.978  1.00 21.04 ? 186 VAL H HA   1 
ATOM   4158 H HB   . VAL B 2 186 ? -14.656 23.691 30.161  1.00 23.13 ? 186 VAL H HB   1 
ATOM   4159 H HG11 . VAL B 2 186 ? -15.037 23.759 28.110  1.00 33.43 ? 186 VAL H HG11 1 
ATOM   4160 H HG12 . VAL B 2 186 ? -15.536 25.029 28.923  1.00 33.43 ? 186 VAL H HG12 1 
ATOM   4161 H HG13 . VAL B 2 186 ? -14.238 25.128 28.012  1.00 33.43 ? 186 VAL H HG13 1 
ATOM   4162 H HG21 . VAL B 2 186 ? -13.083 22.461 28.743  1.00 32.26 ? 186 VAL H HG21 1 
ATOM   4163 H HG22 . VAL B 2 186 ? -12.062 23.673 28.852  1.00 32.26 ? 186 VAL H HG22 1 
ATOM   4164 H HG23 . VAL B 2 186 ? -12.403 22.805 30.137  1.00 32.26 ? 186 VAL H HG23 1 
ATOM   4165 N N    . VAL B 2 187 ? -13.361 24.429 32.847  1.00 16.13 ? 187 VAL H N    1 
ATOM   4166 C CA   . VAL B 2 187 ? -12.741 23.824 34.012  1.00 17.27 ? 187 VAL H CA   1 
ATOM   4167 C C    . VAL B 2 187 ? -13.765 22.906 34.656  1.00 20.43 ? 187 VAL H C    1 
ATOM   4168 O O    . VAL B 2 187 ? -14.967 23.190 34.634  1.00 18.50 ? 187 VAL H O    1 
ATOM   4169 C CB   . VAL B 2 187 ? -12.233 24.926 34.962  1.00 17.84 ? 187 VAL H CB   1 
ATOM   4170 C CG1  . VAL B 2 187 ? -13.363 25.864 35.461  1.00 18.44 ? 187 VAL H CG1  1 
ATOM   4171 C CG2  . VAL B 2 187 ? -11.438 24.348 36.136  1.00 15.29 ? 187 VAL H CG2  1 
ATOM   4172 H H    . VAL B 2 187 ? -14.212 24.537 32.913  1.00 19.42 ? 187 VAL H H    1 
ATOM   4173 H HA   . VAL B 2 187 ? -11.983 23.272 33.763  1.00 20.78 ? 187 VAL H HA   1 
ATOM   4174 H HB   . VAL B 2 187 ? -11.629 25.475 34.440  1.00 21.47 ? 187 VAL H HB   1 
ATOM   4175 H HG11 . VAL B 2 187 ? -12.974 26.560 36.014  1.00 22.19 ? 187 VAL H HG11 1 
ATOM   4176 H HG12 . VAL B 2 187 ? -13.806 26.259 34.694  1.00 22.19 ? 187 VAL H HG12 1 
ATOM   4177 H HG13 . VAL B 2 187 ? -13.998 25.345 35.979  1.00 22.19 ? 187 VAL H HG13 1 
ATOM   4178 H HG21 . VAL B 2 187 ? -11.855 24.626 36.967  1.00 18.41 ? 187 VAL H HG21 1 
ATOM   4179 H HG22 . VAL B 2 187 ? -11.440 23.380 36.073  1.00 18.41 ? 187 VAL H HG22 1 
ATOM   4180 H HG23 . VAL B 2 187 ? -10.528 24.681 36.096  1.00 18.41 ? 187 VAL H HG23 1 
ATOM   4181 N N    . THR B 2 188 ? -13.297 21.779 35.177  1.00 18.65 ? 188 THR H N    1 
ATOM   4182 C CA   . THR B 2 188 ? -14.117 20.881 35.968  1.00 20.15 ? 188 THR H CA   1 
ATOM   4183 C C    . THR B 2 188 ? -13.747 21.058 37.424  1.00 21.81 ? 188 THR H C    1 
ATOM   4184 O O    . THR B 2 188 ? -12.569 21.263 37.743  1.00 22.06 ? 188 THR H O    1 
ATOM   4185 C CB   . THR B 2 188 ? -13.933 19.422 35.548  1.00 21.31 ? 188 THR H CB   1 
ATOM   4186 O OG1  . THR B 2 188 ? -12.551 19.038 35.620  1.00 23.47 ? 188 THR H OG1  1 
ATOM   4187 C CG2  . THR B 2 188 ? -14.503 19.231 34.128  1.00 19.96 ? 188 THR H CG2  1 
ATOM   4188 H H    . THR B 2 188 ? -12.486 21.509 35.081  1.00 22.44 ? 188 THR H H    1 
ATOM   4189 H HA   . THR B 2 188 ? -15.056 21.092 35.846  1.00 24.24 ? 188 THR H HA   1 
ATOM   4190 H HB   . THR B 2 188 ? -14.413 18.833 36.150  1.00 25.63 ? 188 THR H HB   1 
ATOM   4191 H HG1  . THR B 2 188 ? -12.450 18.267 35.300  1.00 28.22 ? 188 THR H HG1  1 
ATOM   4192 H HG21 . THR B 2 188 ? -14.379 18.312 33.841  1.00 24.01 ? 188 THR H HG21 1 
ATOM   4193 H HG22 . THR B 2 188 ? -15.450 19.438 34.120  1.00 24.01 ? 188 THR H HG22 1 
ATOM   4194 H HG23 . THR B 2 188 ? -14.047 19.819 33.505  1.00 24.01 ? 188 THR H HG23 1 
ATOM   4195 N N    . VAL B 2 189 ? -14.757 21.021 38.294  1.00 21.97 ? 189 VAL H N    1 
ATOM   4196 C CA   . VAL B 2 189 ? -14.563 21.257 39.725  1.00 24.28 ? 189 VAL H CA   1 
ATOM   4197 C C    . VAL B 2 189 ? -15.535 20.386 40.508  1.00 32.55 ? 189 VAL H C    1 
ATOM   4198 O O    . VAL B 2 189 ? -16.510 19.846 39.941  1.00 22.52 ? 189 VAL H O    1 
ATOM   4199 C CB   . VAL B 2 189 ? -14.766 22.730 40.120  1.00 24.67 ? 189 VAL H CB   1 
ATOM   4200 C CG1  . VAL B 2 189 ? -13.783 23.620 39.389  1.00 24.04 ? 189 VAL H CG1  1 
ATOM   4201 C CG2  . VAL B 2 189 ? -16.200 23.146 39.881  1.00 27.41 ? 189 VAL H CG2  1 
ATOM   4202 H H    . VAL B 2 189 ? -15.574 20.860 38.078  1.00 26.43 ? 189 VAL H H    1 
ATOM   4203 H HA   . VAL B 2 189 ? -13.650 21.005 39.935  1.00 29.20 ? 189 VAL H HA   1 
ATOM   4204 H HB   . VAL B 2 189 ? -14.592 22.837 41.068  1.00 29.66 ? 189 VAL H HB   1 
ATOM   4205 H HG11 . VAL B 2 189 ? -13.883 24.531 39.708  1.00 28.91 ? 189 VAL H HG11 1 
ATOM   4206 H HG12 . VAL B 2 189 ? -12.882 23.306 39.565  1.00 28.91 ? 189 VAL H HG12 1 
ATOM   4207 H HG13 . VAL B 2 189 ? -13.967 23.580 38.438  1.00 28.91 ? 189 VAL H HG13 1 
ATOM   4208 H HG21 . VAL B 2 189 ? -16.257 24.115 39.905  1.00 32.95 ? 189 VAL H HG21 1 
ATOM   4209 H HG22 . VAL B 2 189 ? -16.483 22.821 39.012  1.00 32.95 ? 189 VAL H HG22 1 
ATOM   4210 H HG23 . VAL B 2 189 ? -16.760 22.765 40.575  1.00 32.95 ? 189 VAL H HG23 1 
ATOM   4211 N N    . PRO B 2 190 ? -15.313 20.248 41.815  1.00 34.50 ? 190 PRO H N    1 
ATOM   4212 C CA   . PRO B 2 190 ? -16.294 19.577 42.666  1.00 38.97 ? 190 PRO H CA   1 
ATOM   4213 C C    . PRO B 2 190 ? -17.652 20.251 42.549  1.00 35.53 ? 190 PRO H C    1 
ATOM   4214 O O    . PRO B 2 190 ? -17.785 21.457 42.753  1.00 39.13 ? 190 PRO H O    1 
ATOM   4215 C CB   . PRO B 2 190 ? -15.689 19.735 44.065  1.00 41.27 ? 190 PRO H CB   1 
ATOM   4216 C CG   . PRO B 2 190 ? -14.206 19.759 43.827  1.00 43.86 ? 190 PRO H CG   1 
ATOM   4217 C CD   . PRO B 2 190 ? -14.086 20.575 42.571  1.00 39.11 ? 190 PRO H CD   1 
ATOM   4218 H HA   . PRO B 2 190 ? -16.376 18.635 42.447  1.00 46.83 ? 190 PRO H HA   1 
ATOM   4219 H HB2  . PRO B 2 190 ? -15.992 20.564 44.467  1.00 49.58 ? 190 PRO H HB2  1 
ATOM   4220 H HB3  . PRO B 2 190 ? -15.941 18.983 44.623  1.00 49.58 ? 190 PRO H HB3  1 
ATOM   4221 H HG2  . PRO B 2 190 ? -13.750 20.183 44.571  1.00 52.69 ? 190 PRO H HG2  1 
ATOM   4222 H HG3  . PRO B 2 190 ? -13.868 18.859 43.700  1.00 52.69 ? 190 PRO H HG3  1 
ATOM   4223 H HD2  . PRO B 2 190 ? -14.054 21.522 42.780  1.00 47.00 ? 190 PRO H HD2  1 
ATOM   4224 H HD3  . PRO B 2 190 ? -13.296 20.319 42.070  1.00 47.00 ? 190 PRO H HD3  1 
ATOM   4225 N N    . SER B 2 191 ? -18.676 19.463 42.232  1.00 36.00 ? 191 SER H N    1 
ATOM   4226 C CA   . SER B 2 191 ? -20.019 20.037 42.209  1.00 37.87 ? 191 SER H CA   1 
ATOM   4227 C C    . SER B 2 191 ? -20.389 20.639 43.557  1.00 35.69 ? 191 SER H C    1 
ATOM   4228 O O    . SER B 2 191 ? -21.158 21.606 43.612  1.00 37.50 ? 191 SER H O    1 
ATOM   4229 C CB   . SER B 2 191 ? -21.032 18.986 41.758  1.00 36.46 ? 191 SER H CB   1 
ATOM   4230 O OG   . SER B 2 191 ? -20.985 17.816 42.560  1.00 45.15 ? 191 SER H OG   1 
ATOM   4231 H H    . SER B 2 191 ? -18.624 18.628 42.034  1.00 43.26 ? 191 SER H H    1 
ATOM   4232 H HA   . SER B 2 191 ? -20.051 20.755 41.557  1.00 45.51 ? 191 SER H HA   1 
ATOM   4233 H HB2  . SER B 2 191 ? -21.922 19.368 41.818  1.00 43.82 ? 191 SER H HB2  1 
ATOM   4234 H HB3  . SER B 2 191 ? -20.837 18.741 40.840  1.00 43.82 ? 191 SER H HB3  1 
ATOM   4235 H HG   . SER B 2 191 ? -21.523 17.243 42.263  1.00 54.24 ? 191 SER H HG   1 
ATOM   4236 N N    . SER B 2 192 ? -19.798 20.140 44.644  1.00 42.44 ? 192 SER H N    1 
ATOM   4237 C CA   . SER B 2 192 ? -20.076 20.735 45.948  1.00 42.21 ? 192 SER H CA   1 
ATOM   4238 C C    . SER B 2 192 ? -19.529 22.164 46.056  1.00 45.52 ? 192 SER H C    1 
ATOM   4239 O O    . SER B 2 192 ? -20.102 22.994 46.777  1.00 42.25 ? 192 SER H O    1 
ATOM   4240 C CB   . SER B 2 192 ? -19.486 19.875 47.063  1.00 42.79 ? 192 SER H CB   1 
ATOM   4241 O OG   . SER B 2 192 ? -18.192 19.412 46.744  1.00 47.07 ? 192 SER H OG   1 
ATOM   4242 H H    . SER B 2 192 ? -19.250 19.478 44.653  1.00 50.99 ? 192 SER H H    1 
ATOM   4243 H HA   . SER B 2 192 ? -21.038 20.768 46.063  1.00 50.71 ? 192 SER H HA   1 
ATOM   4244 H HB2  . SER B 2 192 ? -19.436 20.407 47.872  1.00 51.40 ? 192 SER H HB2  1 
ATOM   4245 H HB3  . SER B 2 192 ? -20.065 19.110 47.204  1.00 51.40 ? 192 SER H HB3  1 
ATOM   4246 H HG   . SER B 2 192 ? -17.869 18.991 47.395  1.00 56.54 ? 192 SER H HG   1 
ATOM   4247 N N    . SER B 2 193 ? -18.436 22.481 45.353  1.00 42.43 ? 193 SER H N    1 
ATOM   4248 C CA   . SER B 2 193 ? -17.844 23.803 45.522  1.00 38.66 ? 193 SER H CA   1 
ATOM   4249 C C    . SER B 2 193 ? -18.654 24.894 44.832  1.00 38.63 ? 193 SER H C    1 
ATOM   4250 O O    . SER B 2 193 ? -18.318 26.075 44.968  1.00 34.71 ? 193 SER H O    1 
ATOM   4251 C CB   . SER B 2 193 ? -16.424 23.844 44.958  1.00 39.21 ? 193 SER H CB   1 
ATOM   4252 O OG   . SER B 2 193 ? -16.426 23.460 43.591  1.00 37.14 ? 193 SER H OG   1 
ATOM   4253 H H    . SER B 2 193 ? -18.036 21.965 44.794  1.00 50.97 ? 193 SER H H    1 
ATOM   4254 H HA   . SER B 2 193 ? -17.801 23.983 46.474  1.00 46.46 ? 193 SER H HA   1 
ATOM   4255 H HB2  . SER B 2 193 ? -16.077 24.747 45.034  1.00 47.11 ? 193 SER H HB2  1 
ATOM   4256 H HB3  . SER B 2 193 ? -15.864 23.231 45.460  1.00 47.11 ? 193 SER H HB3  1 
ATOM   4257 H HG   . SER B 2 193 ? -15.647 23.263 43.347  1.00 44.63 ? 193 SER H HG   1 
ATOM   4258 N N    . LEU B 2 194 ? -19.688 24.534 44.076  1.00 33.18 ? 194 LEU H N    1 
ATOM   4259 C CA   . LEU B 2 194 ? -20.383 25.521 43.267  1.00 35.05 ? 194 LEU H CA   1 
ATOM   4260 C C    . LEU B 2 194 ? -21.084 26.565 44.122  1.00 40.06 ? 194 LEU H C    1 
ATOM   4261 O O    . LEU B 2 194 ? -21.321 27.682 43.652  1.00 38.84 ? 194 LEU H O    1 
ATOM   4262 C CB   . LEU B 2 194 ? -21.388 24.812 42.366  1.00 34.82 ? 194 LEU H CB   1 
ATOM   4263 C CG   . LEU B 2 194 ? -20.813 24.174 41.104  1.00 33.81 ? 194 LEU H CG   1 
ATOM   4264 C CD1  . LEU B 2 194 ? -21.958 23.616 40.258  1.00 30.29 ? 194 LEU H CD1  1 
ATOM   4265 C CD2  . LEU B 2 194 ? -19.953 25.133 40.308  1.00 35.29 ? 194 LEU H CD2  1 
ATOM   4266 H H    . LEU B 2 194 ? -20.001 23.735 44.016  1.00 39.87 ? 194 LEU H H    1 
ATOM   4267 H HA   . LEU B 2 194 ? -19.739 25.987 42.710  1.00 42.13 ? 194 LEU H HA   1 
ATOM   4268 H HB2  . LEU B 2 194 ? -21.810 24.106 42.880  1.00 41.85 ? 194 LEU H HB2  1 
ATOM   4269 H HB3  . LEU B 2 194 ? -22.052 25.460 42.084  1.00 41.85 ? 194 LEU H HB3  1 
ATOM   4270 H HG   . LEU B 2 194 ? -20.224 23.447 41.360  1.00 40.64 ? 194 LEU H HG   1 
ATOM   4271 H HD11 . LEU B 2 194 ? -21.590 23.208 39.459  1.00 36.41 ? 194 LEU H HD11 1 
ATOM   4272 H HD12 . LEU B 2 194 ? -22.440 22.953 40.776  1.00 36.41 ? 194 LEU H HD12 1 
ATOM   4273 H HD13 . LEU B 2 194 ? -22.553 24.342 40.015  1.00 36.41 ? 194 LEU H HD13 1 
ATOM   4274 H HD21 . LEU B 2 194 ? -19.688 24.705 39.479  1.00 42.41 ? 194 LEU H HD21 1 
ATOM   4275 H HD22 . LEU B 2 194 ? -20.466 25.934 40.118  1.00 42.41 ? 194 LEU H HD22 1 
ATOM   4276 H HD23 . LEU B 2 194 ? -19.167 25.360 40.830  1.00 42.41 ? 194 LEU H HD23 1 
ATOM   4277 N N    . GLY B 2 195 ? -21.429 26.225 45.362  1.00 46.15 ? 195 GLY H N    1 
ATOM   4278 C CA   . GLY B 2 195 ? -22.094 27.172 46.232  1.00 40.43 ? 195 GLY H CA   1 
ATOM   4279 C C    . GLY B 2 195 ? -21.105 27.854 47.148  1.00 43.75 ? 195 GLY H C    1 
ATOM   4280 O O    . GLY B 2 195 ? -21.409 28.903 47.730  1.00 49.72 ? 195 GLY H O    1 
ATOM   4281 H H    . GLY B 2 195 ? -21.287 25.454 45.716  1.00 55.45 ? 195 GLY H H    1 
ATOM   4282 H HA2  . GLY B 2 195 ? -22.541 27.847 45.698  1.00 48.57 ? 195 GLY H HA2  1 
ATOM   4283 H HA3  . GLY B 2 195 ? -22.753 26.710 46.774  1.00 48.57 ? 195 GLY H HA3  1 
ATOM   4284 N N    . THR B 2 196 ? -19.904 27.281 47.257  1.00 40.45 ? 196 THR H N    1 
ATOM   4285 C CA   . THR B 2 196 ? -18.890 27.788 48.174  1.00 38.72 ? 196 THR H CA   1 
ATOM   4286 C C    . THR B 2 196 ? -17.899 28.727 47.499  1.00 42.25 ? 196 THR H C    1 
ATOM   4287 O O    . THR B 2 196 ? -17.532 29.757 48.076  1.00 42.71 ? 196 THR H O    1 
ATOM   4288 C CB   . THR B 2 196 ? -18.138 26.617 48.823  1.00 44.17 ? 196 THR H CB   1 
ATOM   4289 O OG1  . THR B 2 196 ? -17.274 25.994 47.864  1.00 45.41 ? 196 THR H OG1  1 
ATOM   4290 C CG2  . THR B 2 196 ? -19.117 25.599 49.353  1.00 40.72 ? 196 THR H CG2  1 
ATOM   4291 H H    . THR B 2 196 ? -19.655 26.593 46.805  1.00 48.60 ? 196 THR H H    1 
ATOM   4292 H HA   . THR B 2 196 ? -19.326 28.286 48.883  1.00 46.53 ? 196 THR H HA   1 
ATOM   4293 H HB   . THR B 2 196 ? -17.603 26.948 49.561  1.00 53.06 ? 196 THR H HB   1 
ATOM   4294 H HG1  . THR B 2 196 ? -16.791 25.421 48.242  1.00 54.56 ? 196 THR H HG1  1 
ATOM   4295 H HG21 . THR B 2 196 ? -18.642 24.892 49.817  1.00 48.92 ? 196 THR H HG21 1 
ATOM   4296 H HG22 . THR B 2 196 ? -19.734 26.022 49.970  1.00 48.92 ? 196 THR H HG22 1 
ATOM   4297 H HG23 . THR B 2 196 ? -19.621 25.211 48.620  1.00 48.92 ? 196 THR H HG23 1 
ATOM   4298 N N    . GLN B 2 197 ? -17.452 28.405 46.285  1.00 41.30 ? 197 GLN H N    1 
ATOM   4299 C CA   . GLN B 2 197 ? -16.362 29.140 45.658  1.00 36.03 ? 197 GLN H CA   1 
ATOM   4300 C C    . GLN B 2 197 ? -16.840 29.921 44.430  1.00 30.97 ? 197 GLN H C    1 
ATOM   4301 O O    . GLN B 2 197 ? -17.786 29.525 43.733  1.00 32.77 ? 197 GLN H O    1 
ATOM   4302 C CB   . GLN B 2 197 ? -15.230 28.174 45.282  1.00 39.59 ? 197 GLN H CB   1 
ATOM   4303 C CG   . GLN B 2 197 ? -14.103 28.800 44.462  1.00 39.62 ? 197 GLN H CG   1 
ATOM   4304 C CD   . GLN B 2 197 ? -13.293 29.800 45.273  1.00 46.85 ? 197 GLN H CD   1 
ATOM   4305 O OE1  . GLN B 2 197 ? -13.294 31.008 44.986  1.00 42.52 ? 197 GLN H OE1  1 
ATOM   4306 N NE2  . GLN B 2 197 ? -12.601 29.303 46.302  1.00 48.54 ? 197 GLN H NE2  1 
ATOM   4307 H H    . GLN B 2 197 ? -17.767 27.763 45.808  1.00 49.62 ? 197 GLN H H    1 
ATOM   4308 H HA   . GLN B 2 197 ? -16.017 29.802 46.278  1.00 43.30 ? 197 GLN H HA   1 
ATOM   4309 H HB2  . GLN B 2 197 ? -14.839 27.825 46.098  1.00 47.57 ? 197 GLN H HB2  1 
ATOM   4310 H HB3  . GLN B 2 197 ? -15.605 27.449 44.758  1.00 47.57 ? 197 GLN H HB3  1 
ATOM   4311 H HG2  . GLN B 2 197 ? -13.503 28.101 44.158  1.00 47.61 ? 197 GLN H HG2  1 
ATOM   4312 H HG3  . GLN B 2 197 ? -14.483 29.266 43.701  1.00 47.61 ? 197 GLN H HG3  1 
ATOM   4313 H HE21 . GLN B 2 197 ? -12.631 28.461 46.473  1.00 58.31 ? 197 GLN H HE21 1 
ATOM   4314 H HE22 . GLN B 2 197 ? -12.126 29.825 46.793  1.00 58.31 ? 197 GLN H HE22 1 
ATOM   4315 N N    . THR B 2 198 ? -16.184 31.058 44.192  1.00 30.47 ? 198 THR H N    1 
ATOM   4316 C CA   . THR B 2 198 ? -16.427 31.890 43.023  1.00 28.73 ? 198 THR H CA   1 
ATOM   4317 C C    . THR B 2 198 ? -15.452 31.526 41.910  1.00 29.72 ? 198 THR H C    1 
ATOM   4318 O O    . THR B 2 198 ? -14.246 31.351 42.139  1.00 23.92 ? 198 THR H O    1 
ATOM   4319 C CB   . THR B 2 198 ? -16.253 33.378 43.333  1.00 35.88 ? 198 THR H CB   1 
ATOM   4320 O OG1  . THR B 2 198 ? -15.073 33.556 44.123  1.00 46.28 ? 198 THR H OG1  1 
ATOM   4321 C CG2  . THR B 2 198 ? -17.433 33.896 44.085  1.00 37.26 ? 198 THR H CG2  1 
ATOM   4322 H H    . THR B 2 198 ? -15.575 31.375 44.711  1.00 36.63 ? 198 THR H H    1 
ATOM   4323 H HA   . THR B 2 198 ? -17.341 31.738 42.735  1.00 34.54 ? 198 THR H HA   1 
ATOM   4324 H HB   . THR B 2 198 ? -16.175 33.879 42.506  1.00 43.12 ? 198 THR H HB   1 
ATOM   4325 H HG1  . THR B 2 198 ? -14.945 34.374 44.268  1.00 55.60 ? 198 THR H HG1  1 
ATOM   4326 H HG21 . THR B 2 198 ? -17.254 34.795 44.404  1.00 44.77 ? 198 THR H HG21 1 
ATOM   4327 H HG22 . THR B 2 198 ? -18.212 33.916 43.508  1.00 44.77 ? 198 THR H HG22 1 
ATOM   4328 H HG23 . THR B 2 198 ? -17.619 33.324 44.846  1.00 44.77 ? 198 THR H HG23 1 
ATOM   4329 N N    . TYR B 2 199 ? -15.969 31.499 40.692  1.00 28.65 ? 199 TYR H N    1 
ATOM   4330 C CA   . TYR B 2 199 ? -15.178 31.168 39.520  1.00 24.36 ? 199 TYR H CA   1 
ATOM   4331 C C    . TYR B 2 199 ? -15.238 32.302 38.517  1.00 22.91 ? 199 TYR H C    1 
ATOM   4332 O O    . TYR B 2 199 ? -16.306 32.643 38.005  1.00 24.35 ? 199 TYR H O    1 
ATOM   4333 C CB   . TYR B 2 199 ? -15.679 29.868 38.921  1.00 28.06 ? 199 TYR H CB   1 
ATOM   4334 C CG   . TYR B 2 199 ? -15.488 28.711 39.850  1.00 34.17 ? 199 TYR H CG   1 
ATOM   4335 C CD1  . TYR B 2 199 ? -14.220 28.228 40.132  1.00 29.08 ? 199 TYR H CD1  1 
ATOM   4336 C CD2  . TYR B 2 199 ? -16.569 28.127 40.485  1.00 27.52 ? 199 TYR H CD2  1 
ATOM   4337 C CE1  . TYR B 2 199 ? -14.039 27.171 41.007  1.00 32.31 ? 199 TYR H CE1  1 
ATOM   4338 C CE2  . TYR B 2 199 ? -16.404 27.074 41.345  1.00 27.38 ? 199 TYR H CE2  1 
ATOM   4339 C CZ   . TYR B 2 199 ? -15.140 26.602 41.616  1.00 34.02 ? 199 TYR H CZ   1 
ATOM   4340 O OH   . TYR B 2 199 ? -14.966 25.554 42.481  1.00 31.13 ? 199 TYR H OH   1 
ATOM   4341 H H    . TYR B 2 199 ? -16.793 31.672 40.517  1.00 34.44 ? 199 TYR H H    1 
ATOM   4342 H HA   . TYR B 2 199 ? -14.245 31.069 39.765  1.00 29.30 ? 199 TYR H HA   1 
ATOM   4343 H HB2  . TYR B 2 199 ? -16.627 29.950 38.729  1.00 33.73 ? 199 TYR H HB2  1 
ATOM   4344 H HB3  . TYR B 2 199 ? -15.190 29.685 38.103  1.00 33.73 ? 199 TYR H HB3  1 
ATOM   4345 H HD1  . TYR B 2 199 ? -13.480 28.620 39.727  1.00 34.96 ? 199 TYR H HD1  1 
ATOM   4346 H HD2  . TYR B 2 199 ? -17.424 28.456 40.325  1.00 33.08 ? 199 TYR H HD2  1 
ATOM   4347 H HE1  . TYR B 2 199 ? -13.185 26.847 41.183  1.00 38.83 ? 199 TYR H HE1  1 
ATOM   4348 H HE2  . TYR B 2 199 ? -17.145 26.679 41.746  1.00 32.92 ? 199 TYR H HE2  1 
ATOM   4349 H HH   . TYR B 2 199 ? -14.151 25.357 42.533  1.00 37.42 ? 199 TYR H HH   1 
ATOM   4350 N N    . ILE B 2 200 ? -14.095 32.897 38.256  1.00 18.28 ? 200 ILE H N    1 
ATOM   4351 C CA   . ILE B 2 200 ? -13.990 34.064 37.408  1.00 18.96 ? 200 ILE H CA   1 
ATOM   4352 C C    . ILE B 2 200 ? -12.934 33.768 36.357  1.00 21.76 ? 200 ILE H C    1 
ATOM   4353 O O    . ILE B 2 200 ? -11.829 33.365 36.695  1.00 18.32 ? 200 ILE H O    1 
ATOM   4354 C CB   . ILE B 2 200 ? -13.621 35.313 38.220  1.00 23.52 ? 200 ILE H CB   1 
ATOM   4355 C CG1  . ILE B 2 200 ? -14.711 35.597 39.262  1.00 22.94 ? 200 ILE H CG1  1 
ATOM   4356 C CG2  . ILE B 2 200 ? -13.396 36.498 37.300  1.00 21.17 ? 200 ILE H CG2  1 
ATOM   4357 C CD1  . ILE B 2 200 ? -14.322 36.699 40.188  1.00 28.08 ? 200 ILE H CD1  1 
ATOM   4358 H H    . ILE B 2 200 ? -13.339 32.634 38.570  1.00 21.99 ? 200 ILE H H    1 
ATOM   4359 H HA   . ILE B 2 200 ? -14.833 34.234 36.961  1.00 22.82 ? 200 ILE H HA   1 
ATOM   4360 H HB   . ILE B 2 200 ? -12.790 35.151 38.693  1.00 28.28 ? 200 ILE H HB   1 
ATOM   4361 H HG12 . ILE B 2 200 ? -15.528 35.856 38.807  1.00 27.59 ? 200 ILE H HG12 1 
ATOM   4362 H HG13 . ILE B 2 200 ? -14.865 34.798 39.790  1.00 27.59 ? 200 ILE H HG13 1 
ATOM   4363 H HG21 . ILE B 2 200 ? -13.388 37.311 37.829  1.00 25.47 ? 200 ILE H HG21 1 
ATOM   4364 H HG22 . ILE B 2 200 ? -12.546 36.389 36.847  1.00 25.47 ? 200 ILE H HG22 1 
ATOM   4365 H HG23 . ILE B 2 200 ? -14.115 36.533 36.650  1.00 25.47 ? 200 ILE H HG23 1 
ATOM   4366 H HD11 . ILE B 2 200 ? -14.880 36.658 40.980  1.00 33.76 ? 200 ILE H HD11 1 
ATOM   4367 H HD12 . ILE B 2 200 ? -13.390 36.591 40.434  1.00 33.76 ? 200 ILE H HD12 1 
ATOM   4368 H HD13 . ILE B 2 200 ? -14.449 37.549 39.737  1.00 33.76 ? 200 ILE H HD13 1 
ATOM   4369 N N    . CYS B 2 201 ? -13.281 33.917 35.093  1.00 18.12 ? 201 CYS H N    1 
ATOM   4370 C CA   . CYS B 2 201 ? -12.284 33.820 34.041  1.00 21.03 ? 201 CYS H CA   1 
ATOM   4371 C C    . CYS B 2 201 ? -11.719 35.181 33.675  1.00 18.71 ? 201 CYS H C    1 
ATOM   4372 O O    . CYS B 2 201 ? -12.453 36.165 33.588  1.00 21.64 ? 201 CYS H O    1 
ATOM   4373 C CB   . CYS B 2 201 ? -12.909 33.095 32.861  1.00 21.20 ? 201 CYS H CB   1 
ATOM   4374 S SG   . CYS B 2 201 ? -14.088 34.104 31.925  1.00 19.58 ? 201 CYS H SG   1 
ATOM   4375 H H    . CYS B 2 201 ? -14.081 34.074 34.819  1.00 21.80 ? 201 CYS H H    1 
ATOM   4376 H HA   . CYS B 2 201 ? -11.509 33.317 34.334  1.00 25.30 ? 201 CYS H HA   1 
ATOM   4377 H HB2  . CYS B 2 201 ? -12.204 32.824 32.253  1.00 25.50 ? 201 CYS H HB2  1 
ATOM   4378 H HB3  . CYS B 2 201 ? -13.382 32.315 33.189  1.00 25.50 ? 201 CYS H HB3  1 
ATOM   4379 N N    . ASN B 2 202 ? -10.396 35.221 33.463  1.00 20.34 ? 202 ASN H N    1 
ATOM   4380 C CA   . ASN B 2 202 ? -9.653  36.446 33.168  1.00 17.14 ? 202 ASN H CA   1 
ATOM   4381 C C    . ASN B 2 202 ? -9.156  36.356 31.734  1.00 21.32 ? 202 ASN H C    1 
ATOM   4382 O O    . ASN B 2 202 ? -8.284  35.543 31.422  1.00 25.58 ? 202 ASN H O    1 
ATOM   4383 C CB   . ASN B 2 202 ? -8.489  36.649 34.132  1.00 24.46 ? 202 ASN H CB   1 
ATOM   4384 C CG   . ASN B 2 202 ? -8.811  36.160 35.497  1.00 24.09 ? 202 ASN H CG   1 
ATOM   4385 O OD1  . ASN B 2 202 ? -8.257  35.174 36.001  1.00 18.56 ? 202 ASN H OD1  1 
ATOM   4386 N ND2  . ASN B 2 202 ? -9.701  36.861 36.130  1.00 21.87 ? 202 ASN H ND2  1 
ATOM   4387 H H    . ASN B 2 202 ? -9.894  34.524 33.486  1.00 24.47 ? 202 ASN H H    1 
ATOM   4388 H HA   . ASN B 2 202 ? -10.249 37.206 33.257  1.00 20.63 ? 202 ASN H HA   1 
ATOM   4389 H HB2  . ASN B 2 202 ? -7.717  36.160 33.808  1.00 29.41 ? 202 ASN H HB2  1 
ATOM   4390 H HB3  . ASN B 2 202 ? -8.282  37.595 34.189  1.00 29.41 ? 202 ASN H HB3  1 
ATOM   4391 H HD21 . ASN B 2 202 ? -9.938  36.638 36.926  1.00 26.31 ? 202 ASN H HD21 1 
ATOM   4392 H HD22 . ASN B 2 202 ? -10.053 37.549 35.753  1.00 26.31 ? 202 ASN H HD22 1 
ATOM   4393 N N    . VAL B 2 203 ? -9.745  37.174 30.873  1.00 19.07 ? 203 VAL H N    1 
ATOM   4394 C CA   . VAL B 2 203 ? -9.486  37.167 29.439  1.00 20.09 ? 203 VAL H CA   1 
ATOM   4395 C C    . VAL B 2 203 ? -8.697  38.420 29.081  1.00 19.59 ? 203 VAL H C    1 
ATOM   4396 O O    . VAL B 2 203 ? -9.150  39.531 29.342  1.00 22.88 ? 203 VAL H O    1 
ATOM   4397 C CB   . VAL B 2 203 ? -10.798 37.101 28.645  1.00 18.11 ? 203 VAL H CB   1 
ATOM   4398 C CG1  . VAL B 2 203 ? -10.538 36.953 27.163  1.00 21.40 ? 203 VAL H CG1  1 
ATOM   4399 C CG2  . VAL B 2 203 ? -11.666 35.968 29.141  1.00 20.58 ? 203 VAL H CG2  1 
ATOM   4400 H H    . VAL B 2 203 ? -10.322 37.767 31.105  1.00 22.94 ? 203 VAL H H    1 
ATOM   4401 H HA   . VAL B 2 203 ? -8.939  36.398 29.216  1.00 24.16 ? 203 VAL H HA   1 
ATOM   4402 H HB   . VAL B 2 203 ? -11.274 37.935 28.782  1.00 21.80 ? 203 VAL H HB   1 
ATOM   4403 H HG11 . VAL B 2 203 ? -11.385 36.844 26.703  1.00 25.74 ? 203 VAL H HG11 1 
ATOM   4404 H HG12 . VAL B 2 203 ? -10.087 37.749 26.841  1.00 25.74 ? 203 VAL H HG12 1 
ATOM   4405 H HG13 . VAL B 2 203 ? -9.979  36.174 27.016  1.00 25.74 ? 203 VAL H HG13 1 
ATOM   4406 H HG21 . VAL B 2 203 ? -12.356 35.788 28.483  1.00 24.76 ? 203 VAL H HG21 1 
ATOM   4407 H HG22 . VAL B 2 203 ? -11.115 35.180 29.267  1.00 24.76 ? 203 VAL H HG22 1 
ATOM   4408 H HG23 . VAL B 2 203 ? -12.072 36.227 29.983  1.00 24.76 ? 203 VAL H HG23 1 
ATOM   4409 N N    . ASN B 2 204 ? -7.535  38.253 28.454  1.00 22.19 ? 204 ASN H N    1 
ATOM   4410 C CA   . ASN B 2 204 ? -6.695  39.380 28.061  1.00 20.89 ? 204 ASN H CA   1 
ATOM   4411 C C    . ASN B 2 204 ? -6.418  39.227 26.576  1.00 26.42 ? 204 ASN H C    1 
ATOM   4412 O O    . ASN B 2 204 ? -5.924  38.185 26.132  1.00 25.86 ? 204 ASN H O    1 
ATOM   4413 C CB   . ASN B 2 204 ? -5.409  39.424 28.895  1.00 27.65 ? 204 ASN H CB   1 
ATOM   4414 C CG   . ASN B 2 204 ? -4.532  40.635 28.607  1.00 36.38 ? 204 ASN H CG   1 
ATOM   4415 O OD1  . ASN B 2 204 ? -3.326  40.635 28.888  1.00 40.48 ? 204 ASN H OD1  1 
ATOM   4416 N ND2  . ASN B 2 204 ? -5.118  41.649 27.979  1.00 38.74 ? 204 ASN H ND2  1 
ATOM   4417 H H    . ASN B 2 204 ? -7.208  37.486 28.244  1.00 26.69 ? 204 ASN H H    1 
ATOM   4418 H HA   . ASN B 2 204 ? -7.148  40.227 28.204  1.00 25.13 ? 204 ASN H HA   1 
ATOM   4419 H HB2  . ASN B 2 204 ? -5.647  39.448 29.835  1.00 33.24 ? 204 ASN H HB2  1 
ATOM   4420 H HB3  . ASN B 2 204 ? -4.887  38.629 28.705  1.00 33.24 ? 204 ASN H HB3  1 
ATOM   4421 H HD21 . ASN B 2 204 ? -5.948  41.596 27.759  1.00 46.54 ? 204 ASN H HD21 1 
ATOM   4422 H HD22 . ASN B 2 204 ? -4.667  42.357 27.793  1.00 46.54 ? 204 ASN H HD22 1 
ATOM   4423 N N    . HIS B 2 205 ? -6.769  40.254 25.816  1.00 26.28 ? 205 HIS H N    1 
ATOM   4424 C CA   . HIS B 2 205 ? -6.517  40.324 24.383  1.00 25.08 ? 205 HIS H CA   1 
ATOM   4425 C C    . HIS B 2 205 ? -5.660  41.557 24.173  1.00 31.32 ? 205 HIS H C    1 
ATOM   4426 O O    . HIS B 2 205 ? -6.182  42.660 23.979  1.00 27.41 ? 205 HIS H O    1 
ATOM   4427 C CB   . HIS B 2 205 ? -7.832  40.356 23.606  1.00 24.10 ? 205 HIS H CB   1 
ATOM   4428 C CG   . HIS B 2 205 ? -7.676  40.416 22.117  1.00 26.70 ? 205 HIS H CG   1 
ATOM   4429 N ND1  . HIS B 2 205 ? -8.083  41.493 21.353  1.00 23.06 ? 205 HIS H ND1  1 
ATOM   4430 C CD2  . HIS B 2 205 ? -7.070  39.559 21.264  1.00 29.29 ? 205 HIS H CD2  1 
ATOM   4431 C CE1  . HIS B 2 205 ? -7.816  41.245 20.082  1.00 25.46 ? 205 HIS H CE1  1 
ATOM   4432 N NE2  . HIS B 2 205 ? -7.181  40.088 20.003  1.00 26.69 ? 205 HIS H NE2  1 
ATOM   4433 H H    . HIS B 2 205 ? -7.170  40.951 26.120  1.00 31.60 ? 205 HIS H H    1 
ATOM   4434 H HA   . HIS B 2 205 ? -6.025  39.550 24.068  1.00 30.16 ? 205 HIS H HA   1 
ATOM   4435 H HB2  . HIS B 2 205 ? -8.334  39.553 23.816  1.00 28.98 ? 205 HIS H HB2  1 
ATOM   4436 H HB3  . HIS B 2 205 ? -8.332  41.141 23.879  1.00 28.98 ? 205 HIS H HB3  1 
ATOM   4437 H HD2  . HIS B 2 205 ? -6.655  38.758 21.490  1.00 35.20 ? 205 HIS H HD2  1 
ATOM   4438 H HE1  . HIS B 2 205 ? -8.039  41.793 19.364  1.00 30.61 ? 205 HIS H HE1  1 
ATOM   4439 H HE2  . HIS B 2 205 ? -6.885  39.727 19.281  1.00 32.09 ? 205 HIS H HE2  1 
ATOM   4440 N N    . LYS B 2 206 ? -4.345  41.350 24.237  1.00 26.85 ? 206 LYS H N    1 
ATOM   4441 C CA   . LYS B 2 206 ? -3.431  42.478 24.205  1.00 29.16 ? 206 LYS H CA   1 
ATOM   4442 C C    . LYS B 2 206 ? -3.473  43.261 22.894  1.00 28.95 ? 206 LYS H C    1 
ATOM   4443 O O    . LYS B 2 206 ? -3.228  44.478 22.944  1.00 27.74 ? 206 LYS H O    1 
ATOM   4444 C CB   . LYS B 2 206 ? -1.997  42.008 24.492  1.00 29.65 ? 206 LYS H CB   1 
ATOM   4445 C CG   . LYS B 2 206 ? -1.761  41.451 25.871  1.00 35.68 ? 206 LYS H CG   1 
ATOM   4446 C CD   . LYS B 2 206 ? -0.285  41.245 26.165  1.00 37.75 ? 206 LYS H CD   1 
ATOM   4447 C CE   . LYS B 2 206 ? -0.060  40.463 27.449  1.00 41.93 ? 206 LYS H CE   1 
ATOM   4448 N NZ   . LYS B 2 206 ? 1.392   40.126 27.628  1.00 46.46 ? 206 LYS H NZ   1 
ATOM   4449 H H    . LYS B 2 206 ? -3.967  40.580 24.299  1.00 32.29 ? 206 LYS H H    1 
ATOM   4450 H HA   . LYS B 2 206 ? -3.697  43.080 24.918  1.00 35.05 ? 206 LYS H HA   1 
ATOM   4451 H HB2  . LYS B 2 206 ? -1.771  41.311 23.856  1.00 35.64 ? 206 LYS H HB2  1 
ATOM   4452 H HB3  . LYS B 2 206 ? -1.400  42.765 24.381  1.00 35.64 ? 206 LYS H HB3  1 
ATOM   4453 H HG2  . LYS B 2 206 ? -2.117  42.068 26.529  1.00 42.87 ? 206 LYS H HG2  1 
ATOM   4454 H HG3  . LYS B 2 206 ? -2.206  40.592 25.947  1.00 42.87 ? 206 LYS H HG3  1 
ATOM   4455 H HD2  . LYS B 2 206 ? 0.120   40.751 25.436  1.00 45.37 ? 206 LYS H HD2  1 
ATOM   4456 H HD3  . LYS B 2 206 ? 0.144   42.110 26.259  1.00 45.37 ? 206 LYS H HD3  1 
ATOM   4457 H HE2  . LYS B 2 206 ? -0.347  40.997 28.207  1.00 50.38 ? 206 LYS H HE2  1 
ATOM   4458 H HE3  . LYS B 2 206 ? -0.566  39.636 27.416  1.00 50.38 ? 206 LYS H HE3  1 
ATOM   4459 H HZ1  . LYS B 2 206 ? 1.501   39.628 28.358  1.00 55.81 ? 206 LYS H HZ1  1 
ATOM   4460 H HZ2  . LYS B 2 206 ? 1.688   39.673 26.922  1.00 55.81 ? 206 LYS H HZ2  1 
ATOM   4461 H HZ3  . LYS B 2 206 ? 1.869   40.873 27.714  1.00 55.81 ? 206 LYS H HZ3  1 
ATOM   4462 N N    . PRO B 2 207 ? -3.730  42.670 21.725  1.00 29.31 ? 207 PRO H N    1 
ATOM   4463 C CA   . PRO B 2 207 ? -3.844  43.501 20.513  1.00 27.72 ? 207 PRO H CA   1 
ATOM   4464 C C    . PRO B 2 207 ? -4.846  44.628 20.619  1.00 32.78 ? 207 PRO H C    1 
ATOM   4465 O O    . PRO B 2 207 ? -4.662  45.663 19.968  1.00 32.62 ? 207 PRO H O    1 
ATOM   4466 C CB   . PRO B 2 207 ? -4.249  42.491 19.436  1.00 26.87 ? 207 PRO H CB   1 
ATOM   4467 C CG   . PRO B 2 207 ? -3.577  41.232 19.902  1.00 26.70 ? 207 PRO H CG   1 
ATOM   4468 C CD   . PRO B 2 207 ? -3.733  41.231 21.394  1.00 26.84 ? 207 PRO H CD   1 
ATOM   4469 H HA   . PRO B 2 207 ? -2.975  43.874 20.299  1.00 33.32 ? 207 PRO H HA   1 
ATOM   4470 H HB2  . PRO B 2 207 ? -5.213  42.390 19.409  1.00 32.31 ? 207 PRO H HB2  1 
ATOM   4471 H HB3  . PRO B 2 207 ? -3.920  42.769 18.567  1.00 32.31 ? 207 PRO H HB3  1 
ATOM   4472 H HG2  . PRO B 2 207 ? -4.012  40.460 19.508  1.00 32.10 ? 207 PRO H HG2  1 
ATOM   4473 H HG3  . PRO B 2 207 ? -2.639  41.247 19.653  1.00 32.10 ? 207 PRO H HG3  1 
ATOM   4474 H HD2  . PRO B 2 207 ? -4.571  40.817 21.655  1.00 32.27 ? 207 PRO H HD2  1 
ATOM   4475 H HD3  . PRO B 2 207 ? -2.991  40.776 21.821  1.00 32.27 ? 207 PRO H HD3  1 
ATOM   4476 N N    . SER B 2 208 ? -5.890  44.483 21.434  1.00 29.62 ? 208 SER H N    1 
ATOM   4477 C CA   . SER B 2 208 ? -6.909  45.512 21.602  1.00 29.25 ? 208 SER H CA   1 
ATOM   4478 C C    . SER B 2 208 ? -6.873  46.142 22.986  1.00 29.59 ? 208 SER H C    1 
ATOM   4479 O O    . SER B 2 208 ? -7.778  46.916 23.323  1.00 31.63 ? 208 SER H O    1 
ATOM   4480 C CB   . SER B 2 208 ? -8.296  44.926 21.325  1.00 31.14 ? 208 SER H CB   1 
ATOM   4481 O OG   . SER B 2 208 ? -8.686  44.015 22.357  1.00 27.94 ? 208 SER H OG   1 
ATOM   4482 H H    . SER B 2 208 ? -6.030  43.781 21.911  1.00 35.61 ? 208 SER H H    1 
ATOM   4483 H HA   . SER B 2 208 ? -6.749  46.215 20.954  1.00 35.16 ? 208 SER H HA   1 
ATOM   4484 H HB2  . SER B 2 208 ? -8.940  45.650 21.285  1.00 37.43 ? 208 SER H HB2  1 
ATOM   4485 H HB3  . SER B 2 208 ? -8.274  44.453 20.479  1.00 37.43 ? 208 SER H HB3  1 
ATOM   4486 H HG   . SER B 2 208 ? -8.081  43.446 22.482  1.00 33.59 ? 208 SER H HG   1 
ATOM   4487 N N    . ASN B 2 209 ? -5.829  45.859 23.769  1.00 29.75 ? 209 ASN H N    1 
ATOM   4488 C CA   . ASN B 2 209 ? -5.660  46.371 25.128  1.00 36.56 ? 209 ASN H CA   1 
ATOM   4489 C C    . ASN B 2 209 ? -6.844  46.050 26.018  1.00 38.23 ? 209 ASN H C    1 
ATOM   4490 O O    . ASN B 2 209 ? -7.102  46.775 26.981  1.00 39.31 ? 209 ASN H O    1 
ATOM   4491 C CB   . ASN B 2 209 ? -5.421  47.881 25.133  1.00 36.10 ? 209 ASN H CB   1 
ATOM   4492 C CG   . ASN B 2 209 ? -4.314  48.286 24.198  1.00 46.44 ? 209 ASN H CG   1 
ATOM   4493 O OD1  . ASN B 2 209 ? -3.227  47.698 24.208  1.00 50.10 ? 209 ASN H OD1  1 
ATOM   4494 N ND2  . ASN B 2 209 ? -4.578  49.288 23.371  1.00 49.08 ? 209 ASN H ND2  1 
ATOM   4495 H H    . ASN B 2 209 ? -5.180  45.351 23.523  1.00 35.76 ? 209 ASN H H    1 
ATOM   4496 H HA   . ASN B 2 209 ? -4.881  45.929 25.502  1.00 43.94 ? 209 ASN H HA   1 
ATOM   4497 H HB2  . ASN B 2 209 ? -6.233  48.332 24.854  1.00 43.39 ? 209 ASN H HB2  1 
ATOM   4498 H HB3  . ASN B 2 209 ? -5.177  48.162 26.029  1.00 43.39 ? 209 ASN H HB3  1 
ATOM   4499 H HD21 . ASN B 2 209 ? -5.349  49.669 23.390  1.00 58.95 ? 209 ASN H HD21 1 
ATOM   4500 H HD22 . ASN B 2 209 ? -3.978  49.557 22.817  1.00 58.95 ? 209 ASN H HD22 1 
ATOM   4501 N N    . THR B 2 210 ? -7.578  44.984 25.708  1.00 31.53 ? 210 THR H N    1 
ATOM   4502 C CA   . THR B 2 210 ? -8.811  44.650 26.413  1.00 32.77 ? 210 THR H CA   1 
ATOM   4503 C C    . THR B 2 210 ? -8.529  43.572 27.452  1.00 35.97 ? 210 THR H C    1 
ATOM   4504 O O    . THR B 2 210 ? -7.799  42.604 27.191  1.00 34.13 ? 210 THR H O    1 
ATOM   4505 C CB   . THR B 2 210 ? -9.893  44.146 25.459  1.00 30.60 ? 210 THR H CB   1 
ATOM   4506 O OG1  . THR B 2 210 ? -9.352  43.075 24.701  1.00 40.26 ? 210 THR H OG1  1 
ATOM   4507 C CG2  . THR B 2 210 ? -10.307 45.245 24.484  1.00 33.68 ? 210 THR H CG2  1 
ATOM   4508 H H    . THR B 2 210 ? -7.377  44.429 25.081  1.00 37.90 ? 210 THR H H    1 
ATOM   4509 H HA   . THR B 2 210 ? -9.144  45.448 26.852  1.00 39.38 ? 210 THR H HA   1 
ATOM   4510 H HB   . THR B 2 210 ? -10.671 43.866 25.964  1.00 36.78 ? 210 THR H HB   1 
ATOM   4511 H HG1  . THR B 2 210 ? -9.911  42.815 24.131  1.00 48.37 ? 210 THR H HG1  1 
ATOM   4512 H HG21 . THR B 2 210 ? -10.974 44.906 23.867  1.00 40.48 ? 210 THR H HG21 1 
ATOM   4513 H HG22 . THR B 2 210 ? -10.681 45.996 24.971  1.00 40.48 ? 210 THR H HG22 1 
ATOM   4514 H HG23 . THR B 2 210 ? -9.537  45.549 23.980  1.00 40.48 ? 210 THR H HG23 1 
ATOM   4515 N N    . LYS B 2 211 ? -9.117  43.741 28.629  1.00 29.14 ? 211 LYS H N    1 
ATOM   4516 C CA   . LYS B 2 211 ? -9.032  42.750 29.694  1.00 32.09 ? 211 LYS H CA   1 
ATOM   4517 C C    . LYS B 2 211 ? -10.429 42.621 30.263  1.00 32.85 ? 211 LYS H C    1 
ATOM   4518 O O    . LYS B 2 211 ? -11.002 43.622 30.688  1.00 34.08 ? 211 LYS H O    1 
ATOM   4519 C CB   . LYS B 2 211 ? -8.024  43.146 30.781  1.00 31.53 ? 211 LYS H CB   1 
ATOM   4520 C CG   . LYS B 2 211 ? -6.584  43.043 30.347  1.00 41.27 ? 211 LYS H CG   1 
ATOM   4521 C CD   . LYS B 2 211 ? -5.591  43.193 31.500  1.00 49.12 ? 211 LYS H CD   1 
ATOM   4522 C CE   . LYS B 2 211 ? -4.444  44.149 31.126  1.00 48.85 ? 211 LYS H CE   1 
ATOM   4523 N NZ   . LYS B 2 211 ? -3.224  43.892 31.954  1.00 46.45 ? 211 LYS H NZ   1 
ATOM   4524 H H    . LYS B 2 211 ? -9.579  44.435 28.840  1.00 35.02 ? 211 LYS H H    1 
ATOM   4525 H HA   . LYS B 2 211 ? -8.736  41.896 29.342  1.00 38.57 ? 211 LYS H HA   1 
ATOM   4526 H HB2  . LYS B 2 211 ? -8.189  44.067 31.038  1.00 37.89 ? 211 LYS H HB2  1 
ATOM   4527 H HB3  . LYS B 2 211 ? -8.144  42.561 31.545  1.00 37.89 ? 211 LYS H HB3  1 
ATOM   4528 H HG2  . LYS B 2 211 ? -6.440  42.174 29.942  1.00 49.59 ? 211 LYS H HG2  1 
ATOM   4529 H HG3  . LYS B 2 211 ? -6.399  43.745 29.703  1.00 49.59 ? 211 LYS H HG3  1 
ATOM   4530 H HD2  . LYS B 2 211 ? -6.049  43.553 32.275  1.00 59.01 ? 211 LYS H HD2  1 
ATOM   4531 H HD3  . LYS B 2 211 ? -5.211  42.326 31.712  1.00 59.01 ? 211 LYS H HD3  1 
ATOM   4532 H HE2  . LYS B 2 211 ? -4.212  44.022 30.193  1.00 58.68 ? 211 LYS H HE2  1 
ATOM   4533 H HE3  . LYS B 2 211 ? -4.727  45.064 31.276  1.00 58.68 ? 211 LYS H HE3  1 
ATOM   4534 H HZ1  . LYS B 2 211 ? -2.567  44.439 31.707  1.00 55.81 ? 211 LYS H HZ1  1 
ATOM   4535 H HZ2  . LYS B 2 211 ? -3.405  44.029 32.815  1.00 55.81 ? 211 LYS H HZ2  1 
ATOM   4536 H HZ3  . LYS B 2 211 ? -2.954  43.050 31.846  1.00 55.81 ? 211 LYS H HZ3  1 
ATOM   4537 N N    . VAL B 2 212 ? -10.984 41.410 30.235  1.00 27.05 ? 212 VAL H N    1 
ATOM   4538 C CA   . VAL B 2 212 ? -12.322 41.133 30.740  1.00 24.22 ? 212 VAL H CA   1 
ATOM   4539 C C    . VAL B 2 212 ? -12.235 40.071 31.826  1.00 29.05 ? 212 VAL H C    1 
ATOM   4540 O O    . VAL B 2 212 ? -11.699 38.981 31.598  1.00 23.30 ? 212 VAL H O    1 
ATOM   4541 C CB   . VAL B 2 212 ? -13.280 40.659 29.635  1.00 27.43 ? 212 VAL H CB   1 
ATOM   4542 C CG1  . VAL B 2 212 ? -14.657 40.411 30.222  1.00 31.79 ? 212 VAL H CG1  1 
ATOM   4543 C CG2  . VAL B 2 212 ? -13.351 41.667 28.512  1.00 34.25 ? 212 VAL H CG2  1 
ATOM   4544 H H    . VAL B 2 212 ? -10.590 40.714 29.918  1.00 32.52 ? 212 VAL H H    1 
ATOM   4545 H HA   . VAL B 2 212 ? -12.667 41.953 31.127  1.00 29.13 ? 212 VAL H HA   1 
ATOM   4546 H HB   . VAL B 2 212 ? -12.947 39.828 29.260  1.00 32.97 ? 212 VAL H HB   1 
ATOM   4547 H HG11 . VAL B 2 212 ? -15.257 40.130 29.513  1.00 38.21 ? 212 VAL H HG11 1 
ATOM   4548 H HG12 . VAL B 2 212 ? -14.593 39.715 30.895  1.00 38.21 ? 212 VAL H HG12 1 
ATOM   4549 H HG13 . VAL B 2 212 ? -14.982 41.232 30.624  1.00 38.21 ? 212 VAL H HG13 1 
ATOM   4550 H HG21 . VAL B 2 212 ? -13.971 41.346 27.838  1.00 41.16 ? 212 VAL H HG21 1 
ATOM   4551 H HG22 . VAL B 2 212 ? -13.659 42.515 28.868  1.00 41.16 ? 212 VAL H HG22 1 
ATOM   4552 H HG23 . VAL B 2 212 ? -12.468 41.771 28.125  1.00 41.16 ? 212 VAL H HG23 1 
ATOM   4553 N N    . ASP B 2 213 ? -12.819 40.371 32.982  1.00 25.00 ? 213 ASP H N    1 
ATOM   4554 C CA   . ASP B 2 213 ? -13.063 39.400 34.040  1.00 19.28 ? 213 ASP H CA   1 
ATOM   4555 C C    . ASP B 2 213 ? -14.544 39.051 34.040  1.00 28.42 ? 213 ASP H C    1 
ATOM   4556 O O    . ASP B 2 213 ? -15.389 39.952 34.102  1.00 30.31 ? 213 ASP H O    1 
ATOM   4557 C CB   . ASP B 2 213 ? -12.645 39.978 35.387  1.00 23.69 ? 213 ASP H CB   1 
ATOM   4558 C CG   . ASP B 2 213 ? -11.184 40.280 35.441  1.00 30.42 ? 213 ASP H CG   1 
ATOM   4559 O OD1  . ASP B 2 213 ? -10.390 39.477 34.903  1.00 25.05 ? 213 ASP H OD1  1 
ATOM   4560 O OD2  . ASP B 2 213 ? -10.824 41.373 35.946  1.00 33.24 ? 213 ASP H OD2  1 
ATOM   4561 H H    . ASP B 2 213 ? -13.092 41.162 33.183  1.00 30.06 ? 213 ASP H H    1 
ATOM   4562 H HA   . ASP B 2 213 ? -12.557 38.586 33.888  1.00 23.20 ? 213 ASP H HA   1 
ATOM   4563 H HB2  . ASP B 2 213 ? -13.130 40.803 35.544  1.00 28.49 ? 213 ASP H HB2  1 
ATOM   4564 H HB3  . ASP B 2 213 ? -12.846 39.336 36.086  1.00 28.49 ? 213 ASP H HB3  1 
ATOM   4565 N N    . LYS B 2 214 ? -14.876 37.762 33.934  1.00 25.72 ? 214 LYS H N    1 
ATOM   4566 C CA   . LYS B 2 214 ? -16.272 37.352 33.899  1.00 21.12 ? 214 LYS H CA   1 
ATOM   4567 C C    . LYS B 2 214 ? -16.514 36.291 34.953  1.00 27.91 ? 214 LYS H C    1 
ATOM   4568 O O    . LYS B 2 214 ? -15.846 35.250 34.971  1.00 30.21 ? 214 LYS H O    1 
ATOM   4569 C CB   . LYS B 2 214 ? -16.669 36.878 32.499  1.00 23.14 ? 214 LYS H CB   1 
ATOM   4570 C CG   . LYS B 2 214 ? -18.051 36.275 32.422  1.00 23.92 ? 214 LYS H CG   1 
ATOM   4571 C CD   . LYS B 2 214 ? -18.459 35.969 31.028  1.00 35.42 ? 214 LYS H CD   1 
ATOM   4572 H H    . LYS B 2 214 ? -14.311 37.116 33.883  1.00 30.92 ? 214 LYS H H    1 
ATOM   4573 H HA   . LYS B 2 214 ? -16.839 38.105 34.127  1.00 25.40 ? 214 LYS H HA   1 
ATOM   4574 H HB2  . LYS B 2 214 ? -16.644 37.636 31.895  1.00 27.83 ? 214 LYS H HB2  1 
ATOM   4575 H HB3  . LYS B 2 214 ? -16.036 36.202 32.209  1.00 27.83 ? 214 LYS H HB3  1 
ATOM   4576 H HG2  . LYS B 2 214 ? -18.066 35.448 32.929  1.00 28.77 ? 214 LYS H HG2  1 
ATOM   4577 H HG3  . LYS B 2 214 ? -18.692 36.902 32.793  1.00 28.77 ? 214 LYS H HG3  1 
ATOM   4578 N N    . ARG B 2 215 ? -17.471 36.565 35.830  1.00 31.12 ? 215 ARG H N    1 
ATOM   4579 C CA   . ARG B 2 215 ? -17.867 35.603 36.830  1.00 29.87 ? 215 ARG H CA   1 
ATOM   4580 C C    . ARG B 2 215 ? -18.870 34.631 36.246  1.00 25.11 ? 215 ARG H C    1 
ATOM   4581 O O    . ARG B 2 215 ? -19.790 35.015 35.513  1.00 26.16 ? 215 ARG H O    1 
ATOM   4582 C CB   . ARG B 2 215 ? -18.455 36.310 38.041  1.00 36.11 ? 215 ARG H CB   1 
ATOM   4583 C CG   . ARG B 2 215 ? -18.625 35.424 39.292  1.00 41.63 ? 215 ARG H CG   1 
ATOM   4584 C CD   . ARG B 2 215 ? -19.632 36.053 40.241  1.00 39.30 ? 215 ARG H CD   1 
ATOM   4585 N NE   . ARG B 2 215 ? -19.014 37.124 41.014  1.00 38.54 ? 215 ARG H NE   1 
ATOM   4586 C CZ   . ARG B 2 215 ? -19.255 37.385 42.294  1.00 39.77 ? 215 ARG H CZ   1 
ATOM   4587 N NH1  . ARG B 2 215 ? -20.176 36.732 42.973  1.00 33.79 ? 215 ARG H NH1  1 
ATOM   4588 N NH2  . ARG B 2 215 ? -18.608 38.386 42.880  1.00 28.40 ? 215 ARG H NH2  1 
ATOM   4589 H H    . ARG B 2 215 ? -17.904 37.308 35.863  1.00 37.40 ? 215 ARG H H    1 
ATOM   4590 H HA   . ARG B 2 215 ? -17.094 35.098 37.128  1.00 35.90 ? 215 ARG H HA   1 
ATOM   4591 H HB2  . ARG B 2 215 ? -17.870 37.045 38.283  1.00 43.39 ? 215 ARG H HB2  1 
ATOM   4592 H HB3  . ARG B 2 215 ? -19.333 36.649 37.804  1.00 43.39 ? 215 ARG H HB3  1 
ATOM   4593 H HG2  . ARG B 2 215 ? -18.949 34.548 39.030  1.00 50.02 ? 215 ARG H HG2  1 
ATOM   4594 H HG3  . ARG B 2 215 ? -17.775 35.340 39.751  1.00 50.02 ? 215 ARG H HG3  1 
ATOM   4595 H HD2  . ARG B 2 215 ? -20.369 36.426 39.732  1.00 47.22 ? 215 ARG H HD2  1 
ATOM   4596 H HD3  . ARG B 2 215 ? -19.962 35.379 40.856  1.00 47.22 ? 215 ARG H HD3  1 
ATOM   4597 H HE   . ARG B 2 215 ? -18.446 37.627 40.609  1.00 46.31 ? 215 ARG H HE   1 
ATOM   4598 H HH11 . ARG B 2 215 ? -20.640 36.118 42.588  1.00 40.61 ? 215 ARG H HH11 1 
ATOM   4599 H HH12 . ARG B 2 215 ? -20.314 36.920 43.801  1.00 40.61 ? 215 ARG H HH12 1 
ATOM   4600 H HH21 . ARG B 2 215 ? -18.042 38.854 42.432  1.00 34.14 ? 215 ARG H HH21 1 
ATOM   4601 H HH22 . ARG B 2 215 ? -18.755 38.566 43.708  1.00 34.14 ? 215 ARG H HH22 1 
ATOM   4602 N N    . VAL B 2 216 ? -18.665 33.361 36.540  1.00 22.21 ? 216 VAL H N    1 
ATOM   4603 C CA   . VAL B 2 216 ? -19.492 32.303 35.996  1.00 23.22 ? 216 VAL H CA   1 
ATOM   4604 C C    . VAL B 2 216 ? -20.285 31.680 37.139  1.00 30.02 ? 216 VAL H C    1 
ATOM   4605 O O    . VAL B 2 216 ? -19.721 30.996 38.001  1.00 26.98 ? 216 VAL H O    1 
ATOM   4606 C CB   . VAL B 2 216 ? -18.662 31.249 35.252  1.00 20.52 ? 216 VAL H CB   1 
ATOM   4607 C CG1  . VAL B 2 216 ? -19.610 30.190 34.694  1.00 23.64 ? 216 VAL H CG1  1 
ATOM   4608 C CG2  . VAL B 2 216 ? -17.852 31.918 34.166  1.00 23.35 ? 216 VAL H CG2  1 
ATOM   4609 H H    . VAL B 2 216 ? -18.040 33.082 37.062  1.00 26.72 ? 216 VAL H H    1 
ATOM   4610 H HA   . VAL B 2 216 ? -20.125 32.692 35.372  1.00 27.93 ? 216 VAL H HA   1 
ATOM   4611 H HB   . VAL B 2 216 ? -18.034 30.809 35.847  1.00 24.68 ? 216 VAL H HB   1 
ATOM   4612 H HG11 . VAL B 2 216 ? -19.108 29.585 34.126  1.00 28.43 ? 216 VAL H HG11 1 
ATOM   4613 H HG12 . VAL B 2 216 ? -20.005 29.700 35.432  1.00 28.43 ? 216 VAL H HG12 1 
ATOM   4614 H HG13 . VAL B 2 216 ? -20.304 30.629 34.179  1.00 28.43 ? 216 VAL H HG13 1 
ATOM   4615 H HG21 . VAL B 2 216 ? -17.350 31.241 33.685  1.00 28.08 ? 216 VAL H HG21 1 
ATOM   4616 H HG22 . VAL B 2 216 ? -18.454 32.377 33.561  1.00 28.08 ? 216 VAL H HG22 1 
ATOM   4617 H HG23 . VAL B 2 216 ? -17.243 32.554 34.573  1.00 28.08 ? 216 VAL H HG23 1 
ATOM   4618 N N    . GLU B 2 217 ? -21.612 31.869 37.106  1.00 34.71 ? 217 GLU H N    1 
ATOM   4619 C CA   . GLU B 2 217 ? -22.503 31.439 38.169  1.00 40.56 ? 217 GLU H CA   1 
ATOM   4620 C C    . GLU B 2 217 ? -23.453 30.348 37.692  1.00 37.70 ? 217 GLU H C    1 
ATOM   4621 O O    . GLU B 2 217 ? -23.789 30.296 36.509  1.00 33.53 ? 217 GLU H O    1 
ATOM   4622 C CB   . GLU B 2 217 ? -23.342 32.620 38.665  1.00 37.12 ? 217 GLU H CB   1 
ATOM   4623 C CG   . GLU B 2 217 ? -22.489 33.768 39.184  1.00 44.66 ? 217 GLU H CG   1 
ATOM   4624 C CD   . GLU B 2 217 ? -22.754 34.045 40.644  1.00 48.55 ? 217 GLU H CD   1 
ATOM   4625 O OE1  . GLU B 2 217 ? -23.748 34.756 40.931  1.00 59.95 ? 217 GLU H OE1  1 
ATOM   4626 O OE2  . GLU B 2 217 ? -21.989 33.498 41.495  1.00 50.83 ? 217 GLU H OE2  1 
ATOM   4627 H H    . GLU B 2 217 ? -22.023 32.256 36.457  1.00 41.71 ? 217 GLU H H    1 
ATOM   4628 H HA   . GLU B 2 217 ? -21.976 31.082 38.902  1.00 48.73 ? 217 GLU H HA   1 
ATOM   4629 H HB2  . GLU B 2 217 ? -23.881 32.954 37.931  1.00 44.61 ? 217 GLU H HB2  1 
ATOM   4630 H HB3  . GLU B 2 217 ? -23.915 32.320 39.388  1.00 44.61 ? 217 GLU H HB3  1 
ATOM   4631 H HG2  . GLU B 2 217 ? -21.551 33.542 39.083  1.00 53.65 ? 217 GLU H HG2  1 
ATOM   4632 H HG3  . GLU B 2 217 ? -22.692 34.572 38.680  1.00 53.65 ? 217 GLU H HG3  1 
ATOM   4633 N N    . PRO B 2 218 ? -23.904 29.467 38.590  1.00 38.42 ? 218 PRO H N    1 
ATOM   4634 C CA   . PRO B 2 218 ? -24.995 28.556 38.240  1.00 41.63 ? 218 PRO H CA   1 
ATOM   4635 C C    . PRO B 2 218 ? -26.257 29.321 37.882  1.00 41.51 ? 218 PRO H C    1 
ATOM   4636 O O    . PRO B 2 218 ? -26.509 30.410 38.401  1.00 41.37 ? 218 PRO H O    1 
ATOM   4637 C CB   . PRO B 2 218 ? -25.185 27.724 39.514  1.00 44.15 ? 218 PRO H CB   1 
ATOM   4638 C CG   . PRO B 2 218 ? -23.842 27.806 40.217  1.00 40.53 ? 218 PRO H CG   1 
ATOM   4639 C CD   . PRO B 2 218 ? -23.364 29.189 39.934  1.00 40.19 ? 218 PRO H CD   1 
ATOM   4640 H HA   . PRO B 2 218 ? -24.743 27.976 37.504  1.00 50.02 ? 218 PRO H HA   1 
ATOM   4641 H HB2  . PRO B 2 218 ? -25.890 28.107 40.060  1.00 53.05 ? 218 PRO H HB2  1 
ATOM   4642 H HB3  . PRO B 2 218 ? -25.404 26.808 39.284  1.00 53.05 ? 218 PRO H HB3  1 
ATOM   4643 H HG2  . PRO B 2 218 ? -23.955 27.664 41.170  1.00 48.70 ? 218 PRO H HG2  1 
ATOM   4644 H HG3  . PRO B 2 218 ? -23.234 27.144 39.853  1.00 48.70 ? 218 PRO H HG3  1 
ATOM   4645 H HD2  . PRO B 2 218 ? -23.718 29.816 40.584  1.00 48.29 ? 218 PRO H HD2  1 
ATOM   4646 H HD3  . PRO B 2 218 ? -22.395 29.225 39.931  1.00 48.29 ? 218 PRO H HD3  1 
ATOM   4647 N N    . LYS B 2 219 ? -27.040 28.731 36.977  1.00 41.02 ? 219 LYS H N    1 
ATOM   4648 C CA   . LYS B 2 219 ? -28.300 29.289 36.477  1.00 44.01 ? 219 LYS H CA   1 
ATOM   4649 C C    . LYS B 2 219 ? -28.041 30.269 35.338  1.00 43.45 ? 219 LYS H C    1 
ATOM   4650 O O    . LYS B 2 219 ? -28.192 29.919 34.166  1.00 46.74 ? 219 LYS H O    1 
ATOM   4651 C CB   . LYS B 2 219 ? -29.087 29.989 37.585  1.00 39.63 ? 219 LYS H CB   1 
ATOM   4652 C CG   . LYS B 2 219 ? -29.936 31.146 37.056  1.00 38.54 ? 219 LYS H CG   1 
ATOM   4653 C CD   . LYS B 2 219 ? -31.159 31.372 37.903  1.00 39.42 ? 219 LYS H CD   1 
ATOM   4654 C CE   . LYS B 2 219 ? -30.928 32.567 38.842  1.00 39.28 ? 219 LYS H CE   1 
ATOM   4655 N NZ   . LYS B 2 219 ? -31.786 32.505 40.047  1.00 44.00 ? 219 LYS H NZ   1 
ATOM   4656 H H    . LYS B 2 219 ? -26.856 27.970 36.620  1.00 49.28 ? 219 LYS H H    1 
ATOM   4657 N N    . GLU C 3 1   ? 3.959   14.474 -11.253 1.00 38.50 ? 1   GLU L N    1 
ATOM   4658 C CA   . GLU C 3 1   ? 4.029   15.085 -9.888  1.00 42.57 ? 1   GLU L CA   1 
ATOM   4659 C C    . GLU C 3 1   ? 3.884   14.043 -8.777  1.00 43.92 ? 1   GLU L C    1 
ATOM   4660 O O    . GLU C 3 1   ? 2.955   13.233 -8.792  1.00 41.35 ? 1   GLU L O    1 
ATOM   4661 C CB   . GLU C 3 1   ? 2.940   16.137 -9.696  1.00 34.76 ? 1   GLU L CB   1 
ATOM   4662 C CG   . GLU C 3 1   ? 3.066   16.888 -8.393  1.00 36.42 ? 1   GLU L CG   1 
ATOM   4663 C CD   . GLU C 3 1   ? 1.910   16.631 -7.438  1.00 48.38 ? 1   GLU L CD   1 
ATOM   4664 O OE1  . GLU C 3 1   ? 0.734   16.792 -7.846  1.00 56.52 ? 1   GLU L OE1  1 
ATOM   4665 O OE2  . GLU C 3 1   ? 2.182   16.256 -6.266  1.00 46.90 ? 1   GLU L OE2  1 
ATOM   4666 H H1   . GLU C 3 1   ? 4.030   15.114 -11.868 1.00 46.26 ? 1   GLU L H1   1 
ATOM   4667 H H2   . GLU C 3 1   ? 4.625   13.893 -11.352 1.00 46.26 ? 1   GLU L H2   1 
ATOM   4668 H H3   . GLU C 3 1   ? 3.181   14.054 -11.351 1.00 46.26 ? 1   GLU L H3   1 
ATOM   4669 H HA   . GLU C 3 1   ? 4.899   15.506 -9.811  1.00 51.15 ? 1   GLU L HA   1 
ATOM   4670 H HB2  . GLU C 3 1   ? 2.994   16.781 -10.420 1.00 41.77 ? 1   GLU L HB2  1 
ATOM   4671 H HB3  . GLU C 3 1   ? 2.075   15.698 -9.706  1.00 41.77 ? 1   GLU L HB3  1 
ATOM   4672 H HG2  . GLU C 3 1   ? 3.885   16.615 -7.951  1.00 43.76 ? 1   GLU L HG2  1 
ATOM   4673 H HG3  . GLU C 3 1   ? 3.091   17.840 -8.580  1.00 43.76 ? 1   GLU L HG3  1 
ATOM   4674 N N    . ILE C 3 2   ? 4.753   14.114 -7.774  1.00 27.68 ? 2   ILE L N    1 
ATOM   4675 C CA   . ILE C 3 2   ? 4.898   13.033 -6.812  1.00 23.34 ? 2   ILE L CA   1 
ATOM   4676 C C    . ILE C 3 2   ? 4.030   13.314 -5.601  1.00 27.14 ? 2   ILE L C    1 
ATOM   4677 O O    . ILE C 3 2   ? 4.170   14.357 -4.941  1.00 21.57 ? 2   ILE L O    1 
ATOM   4678 C CB   . ILE C 3 2   ? 6.358   12.825 -6.388  1.00 21.78 ? 2   ILE L CB   1 
ATOM   4679 C CG1  . ILE C 3 2   ? 7.331   12.633 -7.573  1.00 29.75 ? 2   ILE L CG1  1 
ATOM   4680 C CG2  . ILE C 3 2   ? 6.401   11.634 -5.450  1.00 24.21 ? 2   ILE L CG2  1 
ATOM   4681 C CD1  . ILE C 3 2   ? 7.022   11.439 -8.459  1.00 36.00 ? 2   ILE L CD1  1 
ATOM   4682 H H    . ILE C 3 2   ? 5.273   14.784 -7.631  1.00 33.28 ? 2   ILE L H    1 
ATOM   4683 H HA   . ILE C 3 2   ? 4.582   12.220 -7.235  1.00 28.06 ? 2   ILE L HA   1 
ATOM   4684 H HB   . ILE C 3 2   ? 6.662   13.634 -5.946  1.00 26.20 ? 2   ILE L HB   1 
ATOM   4685 H HG12 . ILE C 3 2   ? 7.299   13.427 -8.130  1.00 35.77 ? 2   ILE L HG12 1 
ATOM   4686 H HG13 . ILE C 3 2   ? 8.226   12.511 -7.220  1.00 35.77 ? 2   ILE L HG13 1 
ATOM   4687 H HG21 . ILE C 3 2   ? 7.322   11.462 -5.200  1.00 29.11 ? 2   ILE L HG21 1 
ATOM   4688 H HG22 . ILE C 3 2   ? 5.876   11.836 -4.659  1.00 29.11 ? 2   ILE L HG22 1 
ATOM   4689 H HG23 . ILE C 3 2   ? 6.031   10.861 -5.904  1.00 29.11 ? 2   ILE L HG23 1 
ATOM   4690 H HD11 . ILE C 3 2   ? 7.680   11.395 -9.170  1.00 43.26 ? 2   ILE L HD11 1 
ATOM   4691 H HD12 . ILE C 3 2   ? 7.059   10.631 -7.924  1.00 43.26 ? 2   ILE L HD12 1 
ATOM   4692 H HD13 . ILE C 3 2   ? 6.134   11.547 -8.835  1.00 43.26 ? 2   ILE L HD13 1 
ATOM   4693 N N    . VAL C 3 3   ? 3.147   12.366 -5.294  1.00 25.98 ? 3   VAL L N    1 
ATOM   4694 C CA   . VAL C 3 3   ? 2.283   12.416 -4.121  1.00 23.70 ? 3   VAL L CA   1 
ATOM   4695 C C    . VAL C 3 3   ? 2.833   11.440 -3.089  1.00 20.17 ? 3   VAL L C    1 
ATOM   4696 O O    . VAL C 3 3   ? 3.145   10.287 -3.415  1.00 19.98 ? 3   VAL L O    1 
ATOM   4697 C CB   . VAL C 3 3   ? 0.827   12.057 -4.466  1.00 25.33 ? 3   VAL L CB   1 
ATOM   4698 C CG1  . VAL C 3 3   ? 0.012   11.877 -3.207  1.00 28.82 ? 3   VAL L CG1  1 
ATOM   4699 C CG2  . VAL C 3 3   ? 0.235   13.102 -5.385  1.00 38.52 ? 3   VAL L CG2  1 
ATOM   4700 H H    . VAL C 3 3   ? 3.028   11.659 -5.768  1.00 31.24 ? 3   VAL L H    1 
ATOM   4701 H HA   . VAL C 3 3   ? 2.300   13.315 -3.756  1.00 28.50 ? 3   VAL L HA   1 
ATOM   4702 H HB   . VAL C 3 3   ? 0.804   11.210 -4.939  1.00 30.46 ? 3   VAL L HB   1 
ATOM   4703 H HG11 . VAL C 3 3   ? -0.902  11.662 -3.451  1.00 34.65 ? 3   VAL L HG11 1 
ATOM   4704 H HG12 . VAL C 3 3   ? 0.394   11.155 -2.684  1.00 34.65 ? 3   VAL L HG12 1 
ATOM   4705 H HG13 . VAL C 3 3   ? 0.033   12.702 -2.697  1.00 34.65 ? 3   VAL L HG13 1 
ATOM   4706 H HG21 . VAL C 3 3   ? -0.678  12.854 -5.600  1.00 46.29 ? 3   VAL L HG21 1 
ATOM   4707 H HG22 . VAL C 3 3   ? 0.247   13.961 -4.936  1.00 46.29 ? 3   VAL L HG22 1 
ATOM   4708 H HG23 . VAL C 3 3   ? 0.765   13.145 -6.197  1.00 46.29 ? 3   VAL L HG23 1 
ATOM   4709 N N    . LEU C 3 4   ? 2.926   11.887 -1.844  1.00 22.12 ? 4   LEU L N    1 
ATOM   4710 C CA   . LEU C 3 4   ? 3.364   11.031 -0.748  1.00 19.09 ? 4   LEU L CA   1 
ATOM   4711 C C    . LEU C 3 4   ? 2.235   10.828 0.254   1.00 18.30 ? 4   LEU L C    1 
ATOM   4712 O O    . LEU C 3 4   ? 1.561   11.783 0.657   1.00 19.84 ? 4   LEU L O    1 
ATOM   4713 C CB   . LEU C 3 4   ? 4.578   11.589 -0.001  1.00 15.03 ? 4   LEU L CB   1 
ATOM   4714 C CG   . LEU C 3 4   ? 5.855   11.930 -0.760  1.00 20.35 ? 4   LEU L CG   1 
ATOM   4715 C CD1  . LEU C 3 4   ? 6.261   10.873 -1.693  1.00 29.19 ? 4   LEU L CD1  1 
ATOM   4716 C CD2  . LEU C 3 4   ? 5.742   13.244 -1.527  1.00 27.28 ? 4   LEU L CD2  1 
ATOM   4717 H H    . LEU C 3 4   ? 2.739   12.692 -1.606  1.00 26.61 ? 4   LEU L H    1 
ATOM   4718 H HA   . LEU C 3 4   ? 3.614   10.177 -1.133  1.00 22.97 ? 4   LEU L HA   1 
ATOM   4719 H HB2  . LEU C 3 4   ? 4.295   12.411 0.431   1.00 18.09 ? 4   LEU L HB2  1 
ATOM   4720 H HB3  . LEU C 3 4   ? 4.829   10.933 0.667   1.00 18.09 ? 4   LEU L HB3  1 
ATOM   4721 H HG   . LEU C 3 4   ? 6.542   12.021 -0.081  1.00 24.48 ? 4   LEU L HG   1 
ATOM   4722 H HD11 . LEU C 3 4   ? 7.073   11.148 -2.146  1.00 35.09 ? 4   LEU L HD11 1 
ATOM   4723 H HD12 . LEU C 3 4   ? 6.420   10.056 -1.195  1.00 35.09 ? 4   LEU L HD12 1 
ATOM   4724 H HD13 . LEU C 3 4   ? 5.552   10.734 -2.340  1.00 35.09 ? 4   LEU L HD13 1 
ATOM   4725 H HD21 . LEU C 3 4   ? 6.590   13.432 -1.958  1.00 32.80 ? 4   LEU L HD21 1 
ATOM   4726 H HD22 . LEU C 3 4   ? 5.043   13.160 -2.195  1.00 32.80 ? 4   LEU L HD22 1 
ATOM   4727 H HD23 . LEU C 3 4   ? 5.522   13.955 -0.905  1.00 32.80 ? 4   LEU L HD23 1 
ATOM   4728 N N    . THR C 3 5   ? 2.053   9.574  0.644   1.00 18.84 ? 5   THR L N    1 
ATOM   4729 C CA   . THR C 3 5   ? 1.047   9.184  1.624   1.00 17.44 ? 5   THR L CA   1 
ATOM   4730 C C    . THR C 3 5   ? 1.682   8.506  2.831   1.00 16.32 ? 5   THR L C    1 
ATOM   4731 O O    . THR C 3 5   ? 2.338   7.471  2.717   1.00 17.68 ? 5   THR L O    1 
ATOM   4732 C CB   . THR C 3 5   ? -0.007  8.275  0.995   1.00 21.62 ? 5   THR L CB   1 
ATOM   4733 O OG1  . THR C 3 5   ? -0.389  8.811  -0.282  1.00 28.82 ? 5   THR L OG1  1 
ATOM   4734 C CG2  . THR C 3 5   ? -1.217  8.187  1.890   1.00 25.63 ? 5   THR L CG2  1 
ATOM   4735 H H    . THR C 3 5   ? 2.514   8.911  0.347   1.00 22.67 ? 5   THR L H    1 
ATOM   4736 H HA   . THR C 3 5   ? 0.622   9.993  1.949   1.00 20.99 ? 5   THR L HA   1 
ATOM   4737 H HB   . THR C 3 5   ? 0.351   7.382  0.878   1.00 26.00 ? 5   THR L HB   1 
ATOM   4738 H HG1  . THR C 3 5   ? -0.857  8.252  -0.700  1.00 34.65 ? 5   THR L HG1  1 
ATOM   4739 H HG21 . THR C 3 5   ? -1.899  7.639  1.471   1.00 30.81 ? 5   THR L HG21 1 
ATOM   4740 H HG22 . THR C 3 5   ? -0.973  7.790  2.740   1.00 30.81 ? 5   THR L HG22 1 
ATOM   4741 H HG23 . THR C 3 5   ? -1.578  9.073  2.048   1.00 30.81 ? 5   THR L HG23 1 
ATOM   4742 N N    . GLN C 3 6   ? 1.448   9.086  3.991   1.00 18.36 ? 6   GLN L N    1 
ATOM   4743 C CA   . GLN C 3 6   ? 2.028   8.584  5.221   1.00 13.11 ? 6   GLN L CA   1 
ATOM   4744 C C    . GLN C 3 6   ? 1.011   7.787  5.993   1.00 16.31 ? 6   GLN L C    1 
ATOM   4745 O O    . GLN C 3 6   ? -0.195  8.060  5.952   1.00 16.64 ? 6   GLN L O    1 
ATOM   4746 C CB   . GLN C 3 6   ? 2.544   9.732  6.092   1.00 15.47 ? 6   GLN L CB   1 
ATOM   4747 C CG   . GLN C 3 6   ? 3.798   10.389 5.514   1.00 13.60 ? 6   GLN L CG   1 
ATOM   4748 C CD   . GLN C 3 6   ? 4.340   11.436 6.457   1.00 14.16 ? 6   GLN L CD   1 
ATOM   4749 O OE1  . GLN C 3 6   ? 4.340   12.594 6.103   1.00 11.60 ? 6   GLN L OE1  1 
ATOM   4750 N NE2  . GLN C 3 6   ? 4.833   11.046 7.625   1.00 13.98 ? 6   GLN L NE2  1 
ATOM   4751 H H    . GLN C 3 6   ? 0.951   9.780  4.094   1.00 22.10 ? 6   GLN L H    1 
ATOM   4752 H HA   . GLN C 3 6   ? 2.776   8.004  5.006   1.00 15.79 ? 6   GLN L HA   1 
ATOM   4753 H HB2  . GLN C 3 6   ? 1.854   10.410 6.163   1.00 18.62 ? 6   GLN L HB2  1 
ATOM   4754 H HB3  . GLN C 3 6   ? 2.762   9.388  6.973   1.00 18.62 ? 6   GLN L HB3  1 
ATOM   4755 H HG2  . GLN C 3 6   ? 4.482   9.715  5.377   1.00 16.38 ? 6   GLN L HG2  1 
ATOM   4756 H HG3  . GLN C 3 6   ? 3.580   10.817 4.671   1.00 16.38 ? 6   GLN L HG3  1 
ATOM   4757 H HE21 . GLN C 3 6   ? 4.840   10.211 7.832   1.00 16.84 ? 6   GLN L HE21 1 
ATOM   4758 H HE22 . GLN C 3 6   ? 5.146   11.627 8.176   1.00 16.84 ? 6   GLN L HE22 1 
ATOM   4759 N N    . SER C 3 7   ? 1.537   6.795  6.706   1.00 15.57 ? 7   SER L N    1 
ATOM   4760 C CA   . SER C 3 7   ? 0.726   5.973  7.579   1.00 17.90 ? 7   SER L CA   1 
ATOM   4761 C C    . SER C 3 7   ? 1.555   5.522  8.770   1.00 17.34 ? 7   SER L C    1 
ATOM   4762 O O    . SER C 3 7   ? 2.788   5.436  8.672   1.00 16.56 ? 7   SER L O    1 
ATOM   4763 C CB   . SER C 3 7   ? 0.137   4.773  6.829   1.00 21.22 ? 7   SER L CB   1 
ATOM   4764 O OG   . SER C 3 7   ? 1.171   3.868  6.533   1.00 25.81 ? 7   SER L OG   1 
ATOM   4765 H H    . SER C 3 7   ? 2.370   6.582  6.698   1.00 18.75 ? 7   SER L H    1 
ATOM   4766 H HA   . SER C 3 7   ? -0.008  6.501  7.930   1.00 21.54 ? 7   SER L HA   1 
ATOM   4767 H HB2  . SER C 3 7   ? -0.525  4.336  7.387   1.00 25.53 ? 7   SER L HB2  1 
ATOM   4768 H HB3  . SER C 3 7   ? -0.273  5.076  6.004   1.00 25.53 ? 7   SER L HB3  1 
ATOM   4769 H HG   . SER C 3 7   ? 0.872   3.230  6.075   1.00 31.04 ? 7   SER L HG   1 
ATOM   4770 N N    . PRO C 3 8   ? 0.916   5.335  9.949   1.00 19.22 ? 8   PRO L N    1 
ATOM   4771 C CA   . PRO C 3 8   ? -0.480  5.674  10.262  1.00 20.88 ? 8   PRO L CA   1 
ATOM   4772 C C    . PRO C 3 8   ? -0.629  7.167  10.413  1.00 17.06 ? 8   PRO L C    1 
ATOM   4773 O O    . PRO C 3 8   ? 0.368   7.874  10.398  1.00 19.81 ? 8   PRO L O    1 
ATOM   4774 C CB   . PRO C 3 8   ? -0.719  4.961  11.591  1.00 20.85 ? 8   PRO L CB   1 
ATOM   4775 C CG   . PRO C 3 8   ? 0.639   5.096  12.276  1.00 19.06 ? 8   PRO L CG   1 
ATOM   4776 C CD   . PRO C 3 8   ? 1.658   4.929  11.158  1.00 20.80 ? 8   PRO L CD   1 
ATOM   4777 H HA   . PRO C 3 8   ? -1.089  5.322  9.594   1.00 25.11 ? 8   PRO L HA   1 
ATOM   4778 H HB2  . PRO C 3 8   ? -1.420  5.403  12.095  1.00 25.08 ? 8   PRO L HB2  1 
ATOM   4779 H HB3  . PRO C 3 8   ? -0.953  4.031  11.442  1.00 25.08 ? 8   PRO L HB3  1 
ATOM   4780 H HG2  . PRO C 3 8   ? 0.715   5.971  12.689  1.00 22.93 ? 8   PRO L HG2  1 
ATOM   4781 H HG3  . PRO C 3 8   ? 0.742   4.403  12.947  1.00 22.93 ? 8   PRO L HG3  1 
ATOM   4782 H HD2  . PRO C 3 8   ? 2.424   5.507  11.301  1.00 25.03 ? 8   PRO L HD2  1 
ATOM   4783 H HD3  . PRO C 3 8   ? 1.947   4.006  11.090  1.00 25.03 ? 8   PRO L HD3  1 
ATOM   4784 N N    . GLY C 3 9   ? -1.838  7.697  10.554  1.00 16.69 ? 9   GLY L N    1 
ATOM   4785 C CA   . GLY C 3 9   ? -1.967  9.100  10.866  1.00 16.38 ? 9   GLY L CA   1 
ATOM   4786 C C    . GLY C 3 9   ? -1.397  9.395  12.232  1.00 17.73 ? 9   GLY L C    1 
ATOM   4787 O O    . GLY C 3 9   ? -0.707  10.400 12.424  1.00 15.32 ? 9   GLY L O    1 
ATOM   4788 H H    . GLY C 3 9   ? -2.580  7.270  10.476  1.00 20.08 ? 9   GLY L H    1 
ATOM   4789 H HA2  . GLY C 3 9   ? -1.490  9.628  10.206  1.00 19.72 ? 9   GLY L HA2  1 
ATOM   4790 H HA3  . GLY C 3 9   ? -2.903  9.354  10.855  1.00 19.72 ? 9   GLY L HA3  1 
ATOM   4791 N N    . THR C 3 10  ? -1.661  8.518  13.190  1.00 15.82 ? 10  THR L N    1 
ATOM   4792 C CA   . THR C 3 10  ? -1.154  8.694  14.533  1.00 17.62 ? 10  THR L CA   1 
ATOM   4793 C C    . THR C 3 10  ? -0.614  7.367  15.016  1.00 16.59 ? 10  THR L C    1 
ATOM   4794 O O    . THR C 3 10  ? -1.306  6.343  14.949  1.00 19.18 ? 10  THR L O    1 
ATOM   4795 C CB   . THR C 3 10  ? -2.258  9.182  15.464  1.00 18.99 ? 10  THR L CB   1 
ATOM   4796 O OG1  . THR C 3 10  ? -2.681  10.478 15.038  1.00 20.91 ? 10  THR L OG1  1 
ATOM   4797 C CG2  . THR C 3 10  ? -1.718  9.274  16.881  1.00 21.52 ? 10  THR L CG2  1 
ATOM   4798 H H    . THR C 3 10  ? -2.135  7.808  13.081  1.00 19.04 ? 10  THR L H    1 
ATOM   4799 H HA   . THR C 3 10  ? -0.434  9.345  14.540  1.00 21.21 ? 10  THR L HA   1 
ATOM   4800 H HB   . THR C 3 10  ? -3.011  8.571  15.451  1.00 22.85 ? 10  THR L HB   1 
ATOM   4801 H HG1  . THR C 3 10  ? -3.156  10.835 15.632  1.00 25.15 ? 10  THR L HG1  1 
ATOM   4802 H HG21 . THR C 3 10  ? -2.306  9.822  17.425  1.00 25.89 ? 10  THR L HG21 1 
ATOM   4803 H HG22 . THR C 3 10  ? -1.663  8.388  17.273  1.00 25.89 ? 10  THR L HG22 1 
ATOM   4804 H HG23 . THR C 3 10  ? -0.834  9.671  16.875  1.00 25.89 ? 10  THR L HG23 1 
ATOM   4805 N N    . LEU C 3 11  ? 0.621   7.391  15.477  1.00 15.59 ? 11  LEU L N    1 
ATOM   4806 C CA   . LEU C 3 11  ? 1.253   6.288  16.177  1.00 15.31 ? 11  LEU L CA   1 
ATOM   4807 C C    . LEU C 3 11  ? 1.223   6.563  17.670  1.00 17.19 ? 11  LEU L C    1 
ATOM   4808 O O    . LEU C 3 11  ? 1.577   7.660  18.116  1.00 16.24 ? 11  LEU L O    1 
ATOM   4809 C CB   . LEU C 3 11  ? 2.676   6.115  15.691  1.00 17.30 ? 11  LEU L CB   1 
ATOM   4810 C CG   . LEU C 3 11  ? 3.338   4.771  15.691  1.00 24.00 ? 11  LEU L CG   1 
ATOM   4811 C CD1  . LEU C 3 11  ? 2.659   3.734  14.821  1.00 25.68 ? 11  LEU L CD1  1 
ATOM   4812 C CD2  . LEU C 3 11  ? 4.810   4.958  15.295  1.00 22.40 ? 11  LEU L CD2  1 
ATOM   4813 H H    . LEU C 3 11  ? 1.141   8.071  15.394  1.00 18.77 ? 11  LEU L H    1 
ATOM   4814 H HA   . LEU C 3 11  ? 0.772   5.462  16.013  1.00 18.44 ? 11  LEU L HA   1 
ATOM   4815 H HB2  . LEU C 3 11  ? 2.700   6.422  14.771  1.00 20.82 ? 11  LEU L HB2  1 
ATOM   4816 H HB3  . LEU C 3 11  ? 3.234   6.684  16.245  1.00 20.82 ? 11  LEU L HB3  1 
ATOM   4817 H HG   . LEU C 3 11  ? 3.269   4.401  16.585  1.00 28.86 ? 11  LEU L HG   1 
ATOM   4818 H HD11 . LEU C 3 11  ? 3.151   2.900  14.881  1.00 30.87 ? 11  LEU L HD11 1 
ATOM   4819 H HD12 . LEU C 3 11  ? 1.750   3.605  15.135  1.00 30.87 ? 11  LEU L HD12 1 
ATOM   4820 H HD13 . LEU C 3 11  ? 2.650   4.048  13.903  1.00 30.87 ? 11  LEU L HD13 1 
ATOM   4821 H HD21 . LEU C 3 11  ? 5.243   4.091  15.267  1.00 26.94 ? 11  LEU L HD21 1 
ATOM   4822 H HD22 . LEU C 3 11  ? 4.851   5.376  14.421  1.00 26.94 ? 11  LEU L HD22 1 
ATOM   4823 H HD23 . LEU C 3 11  ? 5.244   5.524  15.953  1.00 26.94 ? 11  LEU L HD23 1 
ATOM   4824 N N    . SER C 3 12  ? 0.762   5.588  18.442  1.00 14.22 ? 12  SER L N    1 
ATOM   4825 C CA   . SER C 3 12  ? 0.562   5.763  19.876  1.00 14.41 ? 12  SER L CA   1 
ATOM   4826 C C    . SER C 3 12  ? 1.455   4.770  20.608  1.00 16.25 ? 12  SER L C    1 
ATOM   4827 O O    . SER C 3 12  ? 1.241   3.558  20.514  1.00 17.15 ? 12  SER L O    1 
ATOM   4828 C CB   . SER C 3 12  ? -0.910  5.588  20.264  1.00 17.02 ? 12  SER L CB   1 
ATOM   4829 O OG   . SER C 3 12  ? -1.750  6.404  19.447  1.00 19.37 ? 12  SER L OG   1 
ATOM   4830 H H    . SER C 3 12  ? 0.554   4.805  18.154  1.00 17.12 ? 12  SER L H    1 
ATOM   4831 H HA   . SER C 3 12  ? 0.830   6.660  20.131  1.00 17.36 ? 12  SER L HA   1 
ATOM   4832 H HB2  . SER C 3 12  ? -1.160  4.659  20.145  1.00 20.48 ? 12  SER L HB2  1 
ATOM   4833 H HB3  . SER C 3 12  ? -1.025  5.846  21.192  1.00 20.48 ? 12  SER L HB3  1 
ATOM   4834 H HG   . SER C 3 12  ? -2.546  6.348  19.708  1.00 23.31 ? 12  SER L HG   1 
ATOM   4835 N N    . LEU C 3 13  ? 2.438   5.290  21.351  1.00 14.76 ? 13  LEU L N    1 
ATOM   4836 C CA   . LEU C 3 13  ? 3.490   4.454  21.929  1.00 14.86 ? 13  LEU L CA   1 
ATOM   4837 C C    . LEU C 3 13  ? 4.028   5.021  23.241  1.00 15.65 ? 13  LEU L C    1 
ATOM   4838 O O    . LEU C 3 13  ? 3.711   6.119  23.664  1.00 16.29 ? 13  LEU L O    1 
ATOM   4839 C CB   . LEU C 3 13  ? 4.678   4.249  20.980  1.00 21.13 ? 13  LEU L CB   1 
ATOM   4840 C CG   . LEU C 3 13  ? 4.416   3.825  19.535  1.00 26.29 ? 13  LEU L CG   1 
ATOM   4841 C CD1  . LEU C 3 13  ? 5.591   4.198  18.629  1.00 26.92 ? 13  LEU L CD1  1 
ATOM   4842 C CD2  . LEU C 3 13  ? 4.186   2.334  19.565  1.00 27.75 ? 13  LEU L CD2  1 
ATOM   4843 H H    . LEU C 3 13  ? 2.516   6.126  21.535  1.00 17.77 ? 13  LEU L H    1 
ATOM   4844 H HA   . LEU C 3 13  ? 3.054   3.608  22.116  1.00 17.90 ? 13  LEU L HA   1 
ATOM   4845 H HB2  . LEU C 3 13  ? 5.161   5.089  20.934  1.00 25.41 ? 13  LEU L HB2  1 
ATOM   4846 H HB3  . LEU C 3 13  ? 5.243   3.563  21.368  1.00 25.41 ? 13  LEU L HB3  1 
ATOM   4847 H HG   . LEU C 3 13  ? 3.645   4.278  19.161  1.00 31.61 ? 13  LEU L HG   1 
ATOM   4848 H HD11 . LEU C 3 13  ? 5.391   3.921  17.722  1.00 32.37 ? 13  LEU L HD11 1 
ATOM   4849 H HD12 . LEU C 3 13  ? 5.721   5.159  18.661  1.00 32.37 ? 13  LEU L HD12 1 
ATOM   4850 H HD13 . LEU C 3 13  ? 6.389   3.746  18.945  1.00 32.37 ? 13  LEU L HD13 1 
ATOM   4851 H HD21 . LEU C 3 13  ? 4.014   2.023  18.662  1.00 33.36 ? 13  LEU L HD21 1 
ATOM   4852 H HD22 . LEU C 3 13  ? 4.977   1.899  19.919  1.00 33.36 ? 13  LEU L HD22 1 
ATOM   4853 H HD23 . LEU C 3 13  ? 3.422   2.144  20.131  1.00 33.36 ? 13  LEU L HD23 1 
ATOM   4854 N N    . SER C 3 14  ? 4.834   4.217  23.910  1.00 17.43 ? 14  SER L N    1 
ATOM   4855 C CA   . SER C 3 14  ? 5.465   4.599  25.152  1.00 14.35 ? 14  SER L CA   1 
ATOM   4856 C C    . SER C 3 14  ? 6.964   4.713  24.999  1.00 15.39 ? 14  SER L C    1 
ATOM   4857 O O    . SER C 3 14  ? 7.574   4.033  24.172  1.00 13.06 ? 14  SER L O    1 
ATOM   4858 C CB   . SER C 3 14  ? 5.142   3.595  26.279  1.00 20.75 ? 14  SER L CB   1 
ATOM   4859 O OG   . SER C 3 14  ? 3.734   3.551  26.517  1.00 23.54 ? 14  SER L OG   1 
ATOM   4860 H H    . SER C 3 14  ? 5.035   3.421  23.654  1.00 20.98 ? 14  SER L H    1 
ATOM   4861 H HA   . SER C 3 14  ? 5.121   5.466  25.418  1.00 17.28 ? 14  SER L HA   1 
ATOM   4862 H HB2  . SER C 3 14  ? 5.447   2.713  26.015  1.00 24.96 ? 14  SER L HB2  1 
ATOM   4863 H HB3  . SER C 3 14  ? 5.593   3.873  27.091  1.00 24.96 ? 14  SER L HB3  1 
ATOM   4864 H HG   . SER C 3 14  ? 3.568   3.052  27.172  1.00 28.30 ? 14  SER L HG   1 
ATOM   4865 N N    . PRO C 3 15  ? 7.610   5.511  25.840  1.00 14.96 ? 15  PRO L N    1 
ATOM   4866 C CA   . PRO C 3 15  ? 9.062   5.578  25.817  1.00 15.32 ? 15  PRO L CA   1 
ATOM   4867 C C    . PRO C 3 15  ? 9.666   4.179  25.905  1.00 15.61 ? 15  PRO L C    1 
ATOM   4868 O O    . PRO C 3 15  ? 9.178   3.307  26.636  1.00 16.42 ? 15  PRO L O    1 
ATOM   4869 C CB   . PRO C 3 15  ? 9.388   6.443  27.044  1.00 18.02 ? 15  PRO L CB   1 
ATOM   4870 C CG   . PRO C 3 15  ? 8.245   7.298  27.182  1.00 21.14 ? 15  PRO L CG   1 
ATOM   4871 C CD   . PRO C 3 15  ? 7.048   6.411  26.860  1.00 18.40 ? 15  PRO L CD   1 
ATOM   4872 H HA   . PRO C 3 15  ? 9.391   6.023  25.020  1.00 18.45 ? 15  PRO L HA   1 
ATOM   4873 H HB2  . PRO C 3 15  ? 9.503   5.882  27.827  1.00 21.68 ? 15  PRO L HB2  1 
ATOM   4874 H HB3  . PRO C 3 15  ? 10.194  6.959  26.884  1.00 21.68 ? 15  PRO L HB3  1 
ATOM   4875 H HG2  . PRO C 3 15  ? 8.192   7.635  28.090  1.00 25.43 ? 15  PRO L HG2  1 
ATOM   4876 H HG3  . PRO C 3 15  ? 8.307   8.036  26.557  1.00 25.43 ? 15  PRO L HG3  1 
ATOM   4877 H HD2  . PRO C 3 15  ? 6.757   5.917  27.643  1.00 22.14 ? 15  PRO L HD2  1 
ATOM   4878 H HD3  . PRO C 3 15  ? 6.312   6.931  26.503  1.00 22.14 ? 15  PRO L HD3  1 
ATOM   4879 N N    . GLY C 3 16  ? 10.724  3.951  25.143  1.00 15.03 ? 16  GLY L N    1 
ATOM   4880 C CA   . GLY C 3 16  ? 11.394  2.674  25.117  1.00 17.58 ? 16  GLY L CA   1 
ATOM   4881 C C    . GLY C 3 16  ? 10.884  1.745  24.041  1.00 15.55 ? 16  GLY L C    1 
ATOM   4882 O O    . GLY C 3 16  ? 11.556  0.752  23.732  1.00 16.59 ? 16  GLY L O    1 
ATOM   4883 H H    . GLY C 3 16  ? 11.076  4.537  24.621  1.00 18.09 ? 16  GLY L H    1 
ATOM   4884 H HA2  . GLY C 3 16  ? 12.342  2.817  24.967  1.00 21.16 ? 16  GLY L HA2  1 
ATOM   4885 H HA3  . GLY C 3 16  ? 11.273  2.236  25.975  1.00 21.16 ? 16  GLY L HA3  1 
ATOM   4886 N N    . GLU C 3 17  ? 9.709   2.017  23.479  1.00 12.76 ? 17  GLU L N    1 
ATOM   4887 C CA   . GLU C 3 17  ? 9.162   1.180  22.410  1.00 12.83 ? 17  GLU L CA   1 
ATOM   4888 C C    . GLU C 3 17  ? 9.627   1.671  21.045  1.00 15.65 ? 17  GLU L C    1 
ATOM   4889 O O    . GLU C 3 17  ? 10.195  2.748  20.904  1.00 14.09 ? 17  GLU L O    1 
ATOM   4890 C CB   . GLU C 3 17  ? 7.635   1.127  22.473  1.00 14.98 ? 17  GLU L CB   1 
ATOM   4891 C CG   . GLU C 3 17  ? 7.128   0.771  23.878  1.00 11.66 ? 17  GLU L CG   1 
ATOM   4892 C CD   . GLU C 3 17  ? 5.635   0.706  24.032  1.00 15.81 ? 17  GLU L CD   1 
ATOM   4893 O OE1  . GLU C 3 17  ? 4.873   1.438  23.331  1.00 14.25 ? 17  GLU L OE1  1 
ATOM   4894 O OE2  . GLU C 3 17  ? 5.187   -0.044 24.919  1.00 24.03 ? 17  GLU L OE2  1 
ATOM   4895 H H    . GLU C 3 17  ? 9.208   2.681  23.699  1.00 15.37 ? 17  GLU L H    1 
ATOM   4896 H HA   . GLU C 3 17  ? 9.490   0.275  22.532  1.00 15.45 ? 17  GLU L HA   1 
ATOM   4897 H HB2  . GLU C 3 17  ? 7.276   1.995  22.232  1.00 18.04 ? 17  GLU L HB2  1 
ATOM   4898 H HB3  . GLU C 3 17  ? 7.313   0.452  21.855  1.00 18.04 ? 17  GLU L HB3  1 
ATOM   4899 H HG2  . GLU C 3 17  ? 7.481   -0.101 24.117  1.00 14.06 ? 17  GLU L HG2  1 
ATOM   4900 H HG3  . GLU C 3 17  ? 7.453   1.442  24.498  1.00 14.06 ? 17  GLU L HG3  1 
ATOM   4901 N N    . ARG C 3 18  ? 9.398   0.851  20.033  1.00 13.31 ? 18  ARG L N    1 
ATOM   4902 C CA   . ARG C 3 18  ? 9.900   1.139  18.688  1.00 12.53 ? 18  ARG L CA   1 
ATOM   4903 C C    . ARG C 3 18  ? 8.814   1.839  17.893  1.00 17.23 ? 18  ARG L C    1 
ATOM   4904 O O    . ARG C 3 18  ? 7.651   1.422  17.940  1.00 13.02 ? 18  ARG L O    1 
ATOM   4905 C CB   . ARG C 3 18  ? 10.268  -0.178 17.999  1.00 14.36 ? 18  ARG L CB   1 
ATOM   4906 C CG   . ARG C 3 18  ? 10.648  -0.102 16.491  1.00 17.64 ? 18  ARG L CG   1 
ATOM   4907 C CD   . ARG C 3 18  ? 11.377  -1.348 16.048  1.00 21.54 ? 18  ARG L CD   1 
ATOM   4908 N NE   . ARG C 3 18  ? 12.476  -1.580 16.977  1.00 29.67 ? 18  ARG L NE   1 
ATOM   4909 C CZ   . ARG C 3 18  ? 13.763  -1.603 16.656  1.00 33.18 ? 18  ARG L CZ   1 
ATOM   4910 N NH1  . ARG C 3 18  ? 14.169  -1.494 15.397  1.00 33.48 ? 18  ARG L NH1  1 
ATOM   4911 N NH2  . ARG C 3 18  ? 14.669  -1.701 17.631  1.00 30.56 ? 18  ARG L NH2  1 
ATOM   4912 H H    . ARG C 3 18  ? 8.953   0.118  20.093  1.00 16.03 ? 18  ARG L H    1 
ATOM   4913 H HA   . ARG C 3 18  ? 10.681  1.714  18.730  1.00 15.10 ? 18  ARG L HA   1 
ATOM   4914 H HB2  . ARG C 3 18  ? 11.030  -0.557 18.464  1.00 17.29 ? 18  ARG L HB2  1 
ATOM   4915 H HB3  . ARG C 3 18  ? 9.506   -0.775 18.068  1.00 17.29 ? 18  ARG L HB3  1 
ATOM   4916 H HG2  . ARG C 3 18  ? 9.842   -0.014 15.959  1.00 21.23 ? 18  ARG L HG2  1 
ATOM   4917 H HG3  . ARG C 3 18  ? 11.228  0.661  16.343  1.00 21.23 ? 18  ARG L HG3  1 
ATOM   4918 H HD2  . ARG C 3 18  ? 10.778  -2.110 16.066  1.00 25.91 ? 18  ARG L HD2  1 
ATOM   4919 H HD3  . ARG C 3 18  ? 11.734  -1.227 15.155  1.00 25.91 ? 18  ARG L HD3  1 
ATOM   4920 H HE   . ARG C 3 18  ? 12.273  -1.713 17.802  1.00 35.66 ? 18  ARG L HE   1 
ATOM   4921 H HH11 . ARG C 3 18  ? 13.593  -1.406 14.765  1.00 40.24 ? 18  ARG L HH11 1 
ATOM   4922 H HH12 . ARG C 3 18  ? 15.009  -1.512 15.213  1.00 40.24 ? 18  ARG L HH12 1 
ATOM   4923 H HH21 . ARG C 3 18  ? 14.415  -1.747 18.451  1.00 36.74 ? 18  ARG L HH21 1 
ATOM   4924 H HH22 . ARG C 3 18  ? 15.507  -1.717 17.438  1.00 36.74 ? 18  ARG L HH22 1 
ATOM   4925 N N    . ALA C 3 19  ? 9.182   2.887  17.159  1.00 13.20 ? 19  ALA L N    1 
ATOM   4926 C CA   . ALA C 3 19  ? 8.272   3.570  16.263  1.00 15.36 ? 19  ALA L CA   1 
ATOM   4927 C C    . ALA C 3 19  ? 8.649   3.239  14.836  1.00 13.42 ? 19  ALA L C    1 
ATOM   4928 O O    . ALA C 3 19  ? 9.812   3.356  14.468  1.00 14.16 ? 19  ALA L O    1 
ATOM   4929 C CB   . ALA C 3 19  ? 8.331   5.087  16.460  1.00 14.83 ? 19  ALA L CB   1 
ATOM   4930 H H    . ALA C 3 19  ? 9.974   3.223  17.167  1.00 15.90 ? 19  ALA L H    1 
ATOM   4931 H HA   . ALA C 3 19  ? 7.366   3.271  16.438  1.00 18.50 ? 19  ALA L HA   1 
ATOM   4932 H HB1  . ALA C 3 19  ? 8.162   5.523  15.610  1.00 17.85 ? 19  ALA L HB1  1 
ATOM   4933 H HB2  . ALA C 3 19  ? 7.657   5.348  17.106  1.00 17.85 ? 19  ALA L HB2  1 
ATOM   4934 H HB3  . ALA C 3 19  ? 9.212   5.329  16.786  1.00 17.85 ? 19  ALA L HB3  1 
ATOM   4935 N N    . THR C 3 20  ? 7.677   2.798  14.057  1.00 12.79 ? 20  THR L N    1 
ATOM   4936 C CA   . THR C 3 20  ? 7.836   2.602  12.626  1.00 15.60 ? 20  THR L CA   1 
ATOM   4937 C C    . THR C 3 20  ? 6.781   3.398  11.865  1.00 14.70 ? 20  THR L C    1 
ATOM   4938 O O    . THR C 3 20  ? 5.582   3.208  12.079  1.00 15.58 ? 20  THR L O    1 
ATOM   4939 C CB   . THR C 3 20  ? 7.752   1.125  12.263  1.00 22.63 ? 20  THR L CB   1 
ATOM   4940 O OG1  . THR C 3 20  ? 8.684   0.390  13.058  1.00 18.21 ? 20  THR L OG1  1 
ATOM   4941 C CG2  . THR C 3 20  ? 8.009   0.915  10.791  1.00 20.28 ? 20  THR L CG2  1 
ATOM   4942 H H    . THR C 3 20  ? 6.890   2.599  14.342  1.00 15.41 ? 20  THR L H    1 
ATOM   4943 H HA   . THR C 3 20  ? 8.706   2.943  12.364  1.00 18.78 ? 20  THR L HA   1 
ATOM   4944 H HB   . THR C 3 20  ? 6.860   0.789  12.442  1.00 27.22 ? 20  THR L HB   1 
ATOM   4945 H HG1  . THR C 3 20  ? 8.605   -0.433 12.906  1.00 21.91 ? 20  THR L HG1  1 
ATOM   4946 H HG21 . THR C 3 20  ? 8.067   -0.033 10.596  1.00 24.39 ? 20  THR L HG21 1 
ATOM   4947 H HG22 . THR C 3 20  ? 7.286   1.299  10.270  1.00 24.39 ? 20  THR L HG22 1 
ATOM   4948 H HG23 . THR C 3 20  ? 8.842   1.341  10.536  1.00 24.39 ? 20  THR L HG23 1 
ATOM   4949 N N    . LEU C 3 21  ? 7.255   4.324  11.035  1.00 15.19 ? 21  LEU L N    1 
ATOM   4950 C CA   . LEU C 3 21  ? 6.448   5.272  10.283  1.00 12.83 ? 21  LEU L CA   1 
ATOM   4951 C C    . LEU C 3 21  ? 6.659   4.987  8.804   1.00 14.94 ? 21  LEU L C    1 
ATOM   4952 O O    . LEU C 3 21  ? 7.811   4.786  8.360   1.00 14.53 ? 21  LEU L O    1 
ATOM   4953 C CB   . LEU C 3 21  ? 6.908   6.687  10.596  1.00 14.96 ? 21  LEU L CB   1 
ATOM   4954 C CG   . LEU C 3 21  ? 6.557   7.252  11.957  1.00 14.61 ? 21  LEU L CG   1 
ATOM   4955 C CD1  . LEU C 3 21  ? 7.599   6.756  12.955  1.00 15.08 ? 21  LEU L CD1  1 
ATOM   4956 C CD2  . LEU C 3 21  ? 6.581   8.743  11.852  1.00 14.95 ? 21  LEU L CD2  1 
ATOM   4957 H H    . LEU C 3 21  ? 8.095   4.426  10.884  1.00 18.29 ? 21  LEU L H    1 
ATOM   4958 H HA   . LEU C 3 21  ? 5.506   5.183  10.498  1.00 15.46 ? 21  LEU L HA   1 
ATOM   4959 H HB2  . LEU C 3 21  ? 7.875   6.706  10.525  1.00 18.01 ? 21  LEU L HB2  1 
ATOM   4960 H HB3  . LEU C 3 21  ? 6.515   7.279  9.936   1.00 18.01 ? 21  LEU L HB3  1 
ATOM   4961 H HG   . LEU C 3 21  ? 5.679   6.975  12.261  1.00 17.59 ? 21  LEU L HG   1 
ATOM   4962 H HD11 . LEU C 3 21  ? 7.407   7.134  13.827  1.00 18.15 ? 21  LEU L HD11 1 
ATOM   4963 H HD12 . LEU C 3 21  ? 7.559   5.787  12.998  1.00 18.15 ? 21  LEU L HD12 1 
ATOM   4964 H HD13 . LEU C 3 21  ? 8.479   7.037  12.659  1.00 18.15 ? 21  LEU L HD13 1 
ATOM   4965 H HD21 . LEU C 3 21  ? 6.318   9.124  12.704  1.00 18.01 ? 21  LEU L HD21 1 
ATOM   4966 H HD22 . LEU C 3 21  ? 7.480   9.028  11.626  1.00 18.01 ? 21  LEU L HD22 1 
ATOM   4967 H HD23 . LEU C 3 21  ? 5.962   9.021  11.159  1.00 18.01 ? 21  LEU L HD23 1 
ATOM   4968 N N    . SER C 3 22  ? 5.564   4.949  8.049   1.00 13.92 ? 22  SER L N    1 
ATOM   4969 C CA   . SER C 3 22  ? 5.610   4.563  6.653   1.00 15.06 ? 22  SER L CA   1 
ATOM   4970 C C    . SER C 3 22  ? 5.302   5.743  5.751   1.00 14.36 ? 22  SER L C    1 
ATOM   4971 O O    . SER C 3 22  ? 4.501   6.619  6.091   1.00 13.67 ? 22  SER L O    1 
ATOM   4972 C CB   . SER C 3 22  ? 4.629   3.423  6.353   1.00 18.00 ? 22  SER L CB   1 
ATOM   4973 O OG   . SER C 3 22  ? 4.983   2.291  7.144   1.00 24.68 ? 22  SER L OG   1 
ATOM   4974 H H    . SER C 3 22  ? 4.777   5.146  8.332   1.00 16.76 ? 22  SER L H    1 
ATOM   4975 H HA   . SER C 3 22  ? 6.508   4.257  6.449   1.00 18.13 ? 22  SER L HA   1 
ATOM   4976 H HB2  . SER C 3 22  ? 3.728   3.704  6.575   1.00 21.67 ? 22  SER L HB2  1 
ATOM   4977 H HB3  . SER C 3 22  ? 4.682   3.190  5.413   1.00 21.67 ? 22  SER L HB3  1 
ATOM   4978 H HG   . SER C 3 22  ? 4.445   1.662  7.002   1.00 29.68 ? 22  SER L HG   1 
ATOM   4979 N N    . CYS C 3 23  ? 5.992   5.769  4.608   1.00 13.22 ? 23  CYS L N    1 
ATOM   4980 C CA   . CYS C 3 23  ? 5.766   6.775  3.582   1.00 14.02 ? 23  CYS L CA   1 
ATOM   4981 C C    . CYS C 3 23  ? 5.806   6.080  2.232   1.00 17.48 ? 23  CYS L C    1 
ATOM   4982 O O    . CYS C 3 23  ? 6.832   5.472  1.888   1.00 19.34 ? 23  CYS L O    1 
ATOM   4983 C CB   . CYS C 3 23  ? 6.835   7.846  3.673   1.00 15.56 ? 23  CYS L CB   1 
ATOM   4984 S SG   . CYS C 3 23  ? 6.684   9.170  2.440   1.00 19.80 ? 23  CYS L SG   1 
ATOM   4985 H H    . CYS C 3 23  ? 6.606   5.202  4.406   1.00 15.92 ? 23  CYS L H    1 
ATOM   4986 H HA   . CYS C 3 23  ? 4.895   7.190  3.683   1.00 16.88 ? 23  CYS L HA   1 
ATOM   4987 H HB2  . CYS C 3 23  ? 6.787   8.256  4.551   1.00 18.73 ? 23  CYS L HB2  1 
ATOM   4988 H HB3  . CYS C 3 23  ? 7.702   7.428  3.549   1.00 18.73 ? 23  CYS L HB3  1 
ATOM   4989 N N    . ARG C 3 24  ? 4.702   6.192  1.488   1.00 16.86 ? 24  ARG L N    1 
ATOM   4990 C CA   . ARG C 3 24  ? 4.540   5.610  0.158   1.00 20.69 ? 24  ARG L CA   1 
ATOM   4991 C C    . ARG C 3 24  ? 4.502   6.723  -0.880  1.00 21.02 ? 24  ARG L C    1 
ATOM   4992 O O    . ARG C 3 24  ? 3.732   7.680  -0.767  1.00 19.33 ? 24  ARG L O    1 
ATOM   4993 C CB   . ARG C 3 24  ? 3.262   4.764  0.058   1.00 21.23 ? 24  ARG L CB   1 
ATOM   4994 C CG   . ARG C 3 24  ? 2.848   4.406  -1.369  1.00 38.17 ? 24  ARG L CG   1 
ATOM   4995 C CD   . ARG C 3 24  ? 1.880   3.208  -1.439  1.00 42.35 ? 24  ARG L CD   1 
ATOM   4996 N NE   . ARG C 3 24  ? 0.783   3.308  -0.480  1.00 52.49 ? 24  ARG L NE   1 
ATOM   4997 C CZ   . ARG C 3 24  ? -0.223  4.174  -0.566  1.00 49.73 ? 24  ARG L CZ   1 
ATOM   4998 N NH1  . ARG C 3 24  ? -0.316  5.039  -1.571  1.00 48.20 ? 24  ARG L NH1  1 
ATOM   4999 N NH2  . ARG C 3 24  ? -1.164  4.167  0.375   1.00 45.46 ? 24  ARG L NH2  1 
ATOM   5000 H H    . ARG C 3 24  ? 4.004   6.622  1.746   1.00 20.30 ? 24  ARG L H    1 
ATOM   5001 H HA   . ARG C 3 24  ? 5.298   5.033  -0.025  1.00 24.89 ? 24  ARG L HA   1 
ATOM   5002 H HB2  . ARG C 3 24  ? 3.403   3.933  0.539   1.00 25.54 ? 24  ARG L HB2  1 
ATOM   5003 H HB3  . ARG C 3 24  ? 2.531   5.259  0.460   1.00 25.54 ? 24  ARG L HB3  1 
ATOM   5004 H HG2  . ARG C 3 24  ? 2.404   5.170  -1.769  1.00 45.87 ? 24  ARG L HG2  1 
ATOM   5005 H HG3  . ARG C 3 24  ? 3.641   4.178  -1.879  1.00 45.87 ? 24  ARG L HG3  1 
ATOM   5006 H HD2  . ARG C 3 24  ? 1.497   3.162  -2.329  1.00 50.88 ? 24  ARG L HD2  1 
ATOM   5007 H HD3  . ARG C 3 24  ? 2.371   2.393  -1.247  1.00 50.88 ? 24  ARG L HD3  1 
ATOM   5008 H HE   . ARG C 3 24  ? 0.787   2.767  0.188   1.00 63.05 ? 24  ARG L HE   1 
ATOM   5009 H HH11 . ARG C 3 24  ? 0.284   5.048  -2.187  1.00 57.90 ? 24  ARG L HH11 1 
ATOM   5010 H HH12 . ARG C 3 24  ? -0.975  5.589  -1.605  1.00 57.90 ? 24  ARG L HH12 1 
ATOM   5011 H HH21 . ARG C 3 24  ? -1.117  3.608  1.027   1.00 54.61 ? 24  ARG L HH21 1 
ATOM   5012 H HH22 . ARG C 3 24  ? -1.820  4.722  0.332   1.00 54.61 ? 24  ARG L HH22 1 
ATOM   5013 N N    . GLN C 3 25  ? 5.335   6.589  -1.888  1.00 21.48 ? 25  GLN L N    1 
ATOM   5014 C CA   . GLN C 3 25  ? 5.508   7.554  -2.962  1.00 23.44 ? 25  GLN L CA   1 
ATOM   5015 C C    . GLN C 3 25  ? 4.801   7.094  -4.241  1.00 23.60 ? 25  GLN L C    1 
ATOM   5016 O O    . GLN C 3 25  ? 4.728   5.896  -4.521  1.00 24.13 ? 25  GLN L O    1 
ATOM   5017 C CB   . GLN C 3 25  ? 7.007   7.703  -3.163  1.00 24.65 ? 25  GLN L CB   1 
ATOM   5018 C CG   . GLN C 3 25  ? 7.480   8.519  -4.252  1.00 33.26 ? 25  GLN L CG   1 
ATOM   5019 C CD   . GLN C 3 25  ? 8.935   8.877  -4.062  1.00 24.69 ? 25  GLN L CD   1 
ATOM   5020 O OE1  . GLN C 3 25  ? 9.299   9.578  -3.148  1.00 26.58 ? 25  GLN L OE1  1 
ATOM   5021 N NE2  . GLN C 3 25  ? 9.802   8.212  -4.836  1.00 27.57 ? 25  GLN L NE2  1 
ATOM   5022 H H    . GLN C 3 25  ? 5.846   5.904  -1.983  1.00 25.84 ? 25  GLN L H    1 
ATOM   5023 H HA   . GLN C 3 25  ? 5.110   8.415  -2.757  1.00 28.19 ? 25  GLN L HA   1 
ATOM   5024 H HB2  . GLN C 3 25  ? 7.374   8.088  -2.352  1.00 29.64 ? 25  GLN L HB2  1 
ATOM   5025 H HB3  . GLN C 3 25  ? 7.373   6.816  -3.305  1.00 29.64 ? 25  GLN L HB3  1 
ATOM   5026 H HG2  . GLN C 3 25  ? 7.389   8.031  -5.085  1.00 39.97 ? 25  GLN L HG2  1 
ATOM   5027 H HG3  . GLN C 3 25  ? 6.963   9.339  -4.289  1.00 39.97 ? 25  GLN L HG3  1 
ATOM   5028 H HE21 . GLN C 3 25  ? 9.516   7.625  -5.396  1.00 33.14 ? 25  GLN L HE21 1 
ATOM   5029 H HE22 . GLN C 3 25  ? 10.645  8.372  -4.774  1.00 33.14 ? 25  GLN L HE22 1 
ATOM   5030 N N    . SER C 3 26  ? 4.272   8.072  -5.005  1.00 27.02 ? 26  SER L N    1 
ATOM   5031 C CA   . SER C 3 26  ? 3.428   7.781  -6.172  1.00 30.68 ? 26  SER L CA   1 
ATOM   5032 C C    . SER C 3 26  ? 4.179   6.993  -7.240  1.00 35.40 ? 26  SER L C    1 
ATOM   5033 O O    . SER C 3 26  ? 3.582   6.170  -7.944  1.00 31.65 ? 26  SER L O    1 
ATOM   5034 C CB   . SER C 3 26  ? 2.916   9.080  -6.813  1.00 26.87 ? 26  SER L CB   1 
ATOM   5035 O OG   . SER C 3 26  ? 2.285   9.929  -5.903  1.00 40.87 ? 26  SER L OG   1 
ATOM   5036 H H    . SER C 3 26  ? 4.388   8.913  -4.865  1.00 32.49 ? 26  SER L H    1 
ATOM   5037 H HA   . SER C 3 26  ? 2.678   7.257  -5.851  1.00 36.87 ? 26  SER L HA   1 
ATOM   5038 H HB2  . SER C 3 26  ? 3.671   9.550  -7.198  1.00 32.31 ? 26  SER L HB2  1 
ATOM   5039 H HB3  . SER C 3 26  ? 2.279   8.848  -7.507  1.00 32.31 ? 26  SER L HB3  1 
ATOM   5040 H HG   . SER C 3 26  ? 1.925   10.569 -6.309  1.00 49.11 ? 26  SER L HG   1 
ATOM   5041 N N    . GLN C 3 27  ? 5.458   7.312  -7.447  1.00 28.30 ? 27  GLN L N    1 
ATOM   5042 C CA   . GLN C 3 27  ? 6.290   6.674  -8.460  1.00 32.03 ? 27  GLN L CA   1 
ATOM   5043 C C    . GLN C 3 27  ? 7.671   6.425  -7.883  1.00 28.74 ? 27  GLN L C    1 
ATOM   5044 O O    . GLN C 3 27  ? 8.102   7.109  -6.960  1.00 24.19 ? 27  GLN L O    1 
ATOM   5045 C CB   . GLN C 3 27  ? 6.485   7.509  -9.757  1.00 31.60 ? 27  GLN L CB   1 
ATOM   5046 C CG   . GLN C 3 27  ? 5.319   8.338  -10.266 1.00 42.01 ? 27  GLN L CG   1 
ATOM   5047 C CD   . GLN C 3 27  ? 5.763   9.669  -10.882 1.00 45.77 ? 27  GLN L CD   1 
ATOM   5048 O OE1  . GLN C 3 27  ? 6.830   9.763  -11.527 1.00 47.78 ? 27  GLN L OE1  1 
ATOM   5049 N NE2  . GLN C 3 27  ? 4.908   10.687 -10.744 1.00 47.40 ? 27  GLN L NE2  1 
ATOM   5050 H H    . GLN C 3 27  ? 5.876   7.913  -6.997  1.00 34.02 ? 27  GLN L H    1 
ATOM   5051 H HA   . GLN C 3 27  ? 5.849   5.845  -8.700  1.00 38.50 ? 27  GLN L HA   1 
ATOM   5052 H HB2  . GLN C 3 27  ? 7.216   8.128  -9.601  1.00 37.98 ? 27  GLN L HB2  1 
ATOM   5053 H HB3  . GLN C 3 27  ? 6.718   6.894  -10.470 1.00 37.98 ? 27  GLN L HB3  1 
ATOM   5054 H HG2  . GLN C 3 27  ? 4.847   7.835  -10.947 1.00 50.48 ? 27  GLN L HG2  1 
ATOM   5055 H HG3  . GLN C 3 27  ? 4.724   8.534  -9.525  1.00 50.48 ? 27  GLN L HG3  1 
ATOM   5056 H HE21 . GLN C 3 27  ? 4.164   10.571 -10.330 1.00 56.94 ? 27  GLN L HE21 1 
ATOM   5057 H HE22 . GLN C 3 27  ? 5.103   11.459 -11.070 1.00 56.94 ? 27  GLN L HE22 1 
ATOM   5058 N N    . SER C 3 28  ? 8.362   5.439  -8.439  1.00 26.39 ? 28  SER L N    1 
ATOM   5059 C CA   . SER C 3 28  ? 9.799   5.328  -8.242  1.00 24.24 ? 28  SER L CA   1 
ATOM   5060 C C    . SER C 3 28  ? 10.505  6.269  -9.215  1.00 30.02 ? 28  SER L C    1 
ATOM   5061 O O    . SER C 3 28  ? 9.987   6.576  -10.290 1.00 28.12 ? 28  SER L O    1 
ATOM   5062 C CB   . SER C 3 28  ? 10.256  3.889  -8.458  1.00 30.28 ? 28  SER L CB   1 
ATOM   5063 O OG   . SER C 3 28  ? 9.973   3.504  -9.786  1.00 37.60 ? 28  SER L OG   1 
ATOM   5064 H H    . SER C 3 28  ? 8.022   4.824  -8.934  1.00 31.72 ? 28  SER L H    1 
ATOM   5065 H HA   . SER C 3 28  ? 10.043  5.572  -7.335  1.00 29.15 ? 28  SER L HA   1 
ATOM   5066 H HB2  . SER C 3 28  ? 11.212  3.829  -8.302  1.00 36.39 ? 28  SER L HB2  1 
ATOM   5067 H HB3  . SER C 3 28  ? 9.782   3.306  -7.845  1.00 36.39 ? 28  SER L HB3  1 
ATOM   5068 H HG   . SER C 3 28  ? 10.149  2.689  -9.893  1.00 45.18 ? 28  SER L HG   1 
ATOM   5069 N N    . VAL C 3 29  ? 11.716  6.695  -8.846  1.00 20.75 ? 29  VAL L N    1 
ATOM   5070 C CA   . VAL C 3 29  ? 12.403  7.736  -9.614  1.00 23.03 ? 29  VAL L CA   1 
ATOM   5071 C C    . VAL C 3 29  ? 13.863  7.400  -9.893  1.00 26.61 ? 29  VAL L C    1 
ATOM   5072 O O    . VAL C 3 29  ? 14.605  8.237  -10.407 1.00 25.96 ? 29  VAL L O    1 
ATOM   5073 C CB   . VAL C 3 29  ? 12.309  9.108  -8.917  1.00 22.77 ? 29  VAL L CB   1 
ATOM   5074 C CG1  . VAL C 3 29  ? 10.832  9.516  -8.756  1.00 21.73 ? 29  VAL L CG1  1 
ATOM   5075 C CG2  . VAL C 3 29  ? 12.974  9.045  -7.541  1.00 21.96 ? 29  VAL L CG2  1 
ATOM   5076 H H    . VAL C 3 29  ? 12.153  6.401  -8.166  1.00 24.97 ? 29  VAL L H    1 
ATOM   5077 H HA   . VAL C 3 29  ? 11.955  7.766  -10.474 1.00 27.70 ? 29  VAL L HA   1 
ATOM   5078 H HB   . VAL C 3 29  ? 12.766  9.771  -9.459  1.00 27.39 ? 29  VAL L HB   1 
ATOM   5079 H HG11 . VAL C 3 29  ? 10.790  10.430 -8.434  1.00 26.14 ? 29  VAL L HG11 1 
ATOM   5080 H HG12 . VAL C 3 29  ? 10.390  9.448  -9.617  1.00 26.14 ? 29  VAL L HG12 1 
ATOM   5081 H HG13 . VAL C 3 29  ? 10.408  8.920  -8.119  1.00 26.14 ? 29  VAL L HG13 1 
ATOM   5082 H HG21 . VAL C 3 29  ? 12.784  9.865  -7.060  1.00 26.41 ? 29  VAL L HG21 1 
ATOM   5083 H HG22 . VAL C 3 29  ? 12.619  8.285  -7.053  1.00 26.41 ? 29  VAL L HG22 1 
ATOM   5084 H HG23 . VAL C 3 29  ? 13.932  8.944  -7.657  1.00 26.41 ? 29  VAL L HG23 1 
ATOM   5085 N N    . GLY C 3 30  ? 14.277  6.183  -9.604  1.00 24.71 ? 30  GLY L N    1 
ATOM   5086 C CA   . GLY C 3 30  ? 15.594  5.701  -9.986  1.00 23.09 ? 30  GLY L CA   1 
ATOM   5087 C C    . GLY C 3 30  ? 16.637  5.802  -8.898  1.00 24.63 ? 30  GLY L C    1 
ATOM   5088 O O    . GLY C 3 30  ? 17.769  5.325  -9.085  1.00 25.17 ? 30  GLY L O    1 
ATOM   5089 H H    . GLY C 3 30  ? 13.806  5.603  -9.178  1.00 29.72 ? 30  GLY L H    1 
ATOM   5090 H HA2  . GLY C 3 30  ? 15.523  4.768  -10.244 1.00 27.77 ? 30  GLY L HA2  1 
ATOM   5091 H HA3  . GLY C 3 30  ? 15.907  6.216  -10.746 1.00 27.77 ? 30  GLY L HA3  1 
ATOM   5092 N N    . TRP C 3 31  ? 16.309  6.490  -7.810  1.00 25.51 ? 31  TRP L N    1 
ATOM   5093 C CA   . TRP C 3 31  ? 17.064  6.523  -6.567  1.00 18.32 ? 31  TRP L CA   1 
ATOM   5094 C C    . TRP C 3 31  ? 16.082  6.892  -5.469  1.00 21.87 ? 31  TRP L C    1 
ATOM   5095 O O    . TRP C 3 31  ? 14.863  6.871  -5.673  1.00 17.77 ? 31  TRP L O    1 
ATOM   5096 C CB   . TRP C 3 31  ? 18.237  7.503  -6.601  1.00 22.97 ? 31  TRP L CB   1 
ATOM   5097 C CG   . TRP C 3 31  ? 17.904  8.938  -6.792  1.00 17.46 ? 31  TRP L CG   1 
ATOM   5098 C CD1  . TRP C 3 31  ? 17.113  9.507  -7.751  1.00 19.23 ? 31  TRP L CD1  1 
ATOM   5099 C CD2  . TRP C 3 31  ? 18.418  10.011 -6.009  1.00 20.64 ? 31  TRP L CD2  1 
ATOM   5100 N NE1  . TRP C 3 31  ? 17.123  10.906 -7.611  1.00 17.52 ? 31  TRP L NE1  1 
ATOM   5101 C CE2  . TRP C 3 31  ? 17.919  11.222 -6.545  1.00 17.46 ? 31  TRP L CE2  1 
ATOM   5102 C CE3  . TRP C 3 31  ? 19.230  10.066 -4.884  1.00 17.53 ? 31  TRP L CE3  1 
ATOM   5103 C CZ2  . TRP C 3 31  ? 18.214  12.456 -5.987  1.00 16.17 ? 31  TRP L CZ2  1 
ATOM   5104 C CZ3  . TRP C 3 31  ? 19.519  11.291 -4.342  1.00 18.49 ? 31  TRP L CZ3  1 
ATOM   5105 C CH2  . TRP C 3 31  ? 19.024  12.466 -4.893  1.00 18.42 ? 31  TRP L CH2  1 
ATOM   5106 H H    . TRP C 3 31  ? 15.604  6.979  -7.766  1.00 30.67 ? 31  TRP L H    1 
ATOM   5107 H HA   . TRP C 3 31  ? 17.433  5.638  -6.421  1.00 22.05 ? 31  TRP L HA   1 
ATOM   5108 H HB2  . TRP C 3 31  ? 18.713  7.432  -5.758  1.00 27.62 ? 31  TRP L HB2  1 
ATOM   5109 H HB3  . TRP C 3 31  ? 18.820  7.248  -7.333  1.00 27.62 ? 31  TRP L HB3  1 
ATOM   5110 H HD1  . TRP C 3 31  ? 16.638  9.038  -8.399  1.00 23.14 ? 31  TRP L HD1  1 
ATOM   5111 H HE1  . TRP C 3 31  ? 16.702  11.466 -8.110  1.00 21.08 ? 31  TRP L HE1  1 
ATOM   5112 H HE3  . TRP C 3 31  ? 19.572  9.288  -4.507  1.00 21.10 ? 31  TRP L HE3  1 
ATOM   5113 H HZ2  . TRP C 3 31  ? 17.874  13.243 -6.345  1.00 19.47 ? 31  TRP L HZ2  1 
ATOM   5114 H HZ3  . TRP C 3 31  ? 20.060  11.336 -3.587  1.00 22.25 ? 31  TRP L HZ3  1 
ATOM   5115 H HH2  . TRP C 3 31  ? 19.251  13.279 -4.504  1.00 22.17 ? 31  TRP L HH2  1 
ATOM   5116 N N    . SER C 3 32  ? 16.598  7.229  -4.282  1.00 17.51 ? 32  SER L N    1 
ATOM   5117 C CA   . SER C 3 32  ? 15.725  7.449  -3.132  1.00 17.97 ? 32  SER L CA   1 
ATOM   5118 C C    . SER C 3 32  ? 15.913  8.841  -2.526  1.00 16.92 ? 32  SER L C    1 
ATOM   5119 O O    . SER C 3 32  ? 16.390  8.968  -1.390  1.00 18.17 ? 32  SER L O    1 
ATOM   5120 C CB   . SER C 3 32  ? 15.963  6.371  -2.070  1.00 23.59 ? 32  SER L CB   1 
ATOM   5121 O OG   . SER C 3 32  ? 15.717  5.061  -2.564  1.00 22.47 ? 32  SER L OG   1 
ATOM   5122 H H    . SER C 3 32  ? 17.438  7.332  -4.126  1.00 21.08 ? 32  SER L H    1 
ATOM   5123 H HA   . SER C 3 32  ? 14.809  7.415  -3.449  1.00 21.62 ? 32  SER L HA   1 
ATOM   5124 H HB2  . SER C 3 32  ? 16.886  6.424  -1.778  1.00 28.37 ? 32  SER L HB2  1 
ATOM   5125 H HB3  . SER C 3 32  ? 15.368  6.537  -1.323  1.00 28.37 ? 32  SER L HB3  1 
ATOM   5126 H HG   . SER C 3 32  ? 14.920  4.994  -2.818  1.00 27.02 ? 32  SER L HG   1 
ATOM   5127 N N    . PRO C 3 33  ? 15.527  9.917  -3.249  1.00 15.00 ? 33  PRO L N    1 
ATOM   5128 C CA   . PRO C 3 33  ? 15.551  11.266 -2.649  1.00 15.75 ? 33  PRO L CA   1 
ATOM   5129 C C    . PRO C 3 33  ? 14.347  11.400 -1.731  1.00 17.68 ? 33  PRO L C    1 
ATOM   5130 O O    . PRO C 3 33  ? 13.379  12.115 -2.023  1.00 15.70 ? 33  PRO L O    1 
ATOM   5131 C CB   . PRO C 3 33  ? 15.466  12.187 -3.876  1.00 14.69 ? 33  PRO L CB   1 
ATOM   5132 C CG   . PRO C 3 33  ? 14.812  11.394 -4.951  1.00 14.86 ? 33  PRO L CG   1 
ATOM   5133 C CD   . PRO C 3 33  ? 14.799  9.932  -4.528  1.00 18.93 ? 33  PRO L CD   1 
ATOM   5134 H HA   . PRO C 3 33  ? 16.383  11.456 -2.189  1.00 18.96 ? 33  PRO L HA   1 
ATOM   5135 H HB2  . PRO C 3 33  ? 14.937  12.970 -3.658  1.00 17.69 ? 33  PRO L HB2  1 
ATOM   5136 H HB3  . PRO C 3 33  ? 16.360  12.453 -4.144  1.00 17.69 ? 33  PRO L HB3  1 
ATOM   5137 H HG2  . PRO C 3 33  ? 13.905  11.715 -5.074  1.00 17.90 ? 33  PRO L HG2  1 
ATOM   5138 H HG3  . PRO C 3 33  ? 15.315  11.500 -5.774  1.00 17.90 ? 33  PRO L HG3  1 
ATOM   5139 H HD2  . PRO C 3 33  ? 13.889  9.620  -4.407  1.00 22.78 ? 33  PRO L HD2  1 
ATOM   5140 H HD3  . PRO C 3 33  ? 15.253  9.382  -5.186  1.00 22.78 ? 33  PRO L HD3  1 
ATOM   5141 N N    . LEU C 3 34  ? 14.412  10.703 -0.596  1.00 17.02 ? 34  LEU L N    1 
ATOM   5142 C CA   . LEU C 3 34  ? 13.324  10.672 0.373   1.00 16.85 ? 34  LEU L CA   1 
ATOM   5143 C C    . LEU C 3 34  ? 13.877  11.131 1.716   1.00 15.10 ? 34  LEU L C    1 
ATOM   5144 O O    . LEU C 3 34  ? 14.866  10.571 2.223   1.00 12.77 ? 34  LEU L O    1 
ATOM   5145 C CB   . LEU C 3 34  ? 12.750  9.271  0.471   1.00 15.90 ? 34  LEU L CB   1 
ATOM   5146 C CG   . LEU C 3 34  ? 11.382  9.474  1.110   1.00 20.69 ? 34  LEU L CG   1 
ATOM   5147 C CD1  . LEU C 3 34  ? 10.162  8.811  0.520   1.00 31.19 ? 34  LEU L CD1  1 
ATOM   5148 C CD2  . LEU C 3 34  ? 11.515  9.230  2.628   1.00 18.94 ? 34  LEU L CD2  1 
ATOM   5149 H H    . LEU C 3 34  ? 15.092  10.230 -0.363  1.00 20.48 ? 34  LEU L H    1 
ATOM   5150 H HA   . LEU C 3 34  ? 12.614  11.278 0.111   1.00 20.28 ? 34  LEU L HA   1 
ATOM   5151 H HB2  . LEU C 3 34  ? 12.655  8.872  -0.408  1.00 19.14 ? 34  LEU L HB2  1 
ATOM   5152 H HB3  . LEU C 3 34  ? 13.304  8.707  1.033   1.00 19.14 ? 34  LEU L HB3  1 
ATOM   5153 H HG   . LEU C 3 34  ? 11.150  10.392 0.899   1.00 24.89 ? 34  LEU L HG   1 
ATOM   5154 H HD11 . LEU C 3 34  ? 9.417   9.432  0.555   1.00 37.49 ? 34  LEU L HD11 1 
ATOM   5155 H HD12 . LEU C 3 34  ? 10.348  8.570  -0.401  1.00 37.49 ? 34  LEU L HD12 1 
ATOM   5156 H HD13 . LEU C 3 34  ? 9.954   8.016  1.035   1.00 37.49 ? 34  LEU L HD13 1 
ATOM   5157 H HD21 . LEU C 3 34  ? 10.635  9.275  3.034   1.00 22.79 ? 34  LEU L HD21 1 
ATOM   5158 H HD22 . LEU C 3 34  ? 11.902  8.353  2.774   1.00 22.79 ? 34  LEU L HD22 1 
ATOM   5159 H HD23 . LEU C 3 34  ? 12.090  9.913  3.008   1.00 22.79 ? 34  LEU L HD23 1 
ATOM   5160 N N    . ALA C 3 35  ? 13.290  12.198 2.247   1.00 9.88  ? 35  ALA L N    1 
ATOM   5161 C CA   . ALA C 3 35  ? 13.721  12.787 3.502   1.00 12.29 ? 35  ALA L CA   1 
ATOM   5162 C C    . ALA C 3 35  ? 12.629  12.709 4.558   1.00 10.63 ? 35  ALA L C    1 
ATOM   5163 O O    . ALA C 3 35  ? 11.430  12.736 4.265   1.00 11.80 ? 35  ALA L O    1 
ATOM   5164 C CB   . ALA C 3 35  ? 14.115  14.258 3.335   1.00 11.44 ? 35  ALA L CB   1 
ATOM   5165 H H    . ALA C 3 35  ? 12.624  12.605 1.888   1.00 11.92 ? 35  ALA L H    1 
ATOM   5166 H HA   . ALA C 3 35  ? 14.487  12.280 3.814   1.00 14.81 ? 35  ALA L HA   1 
ATOM   5167 H HB1  . ALA C 3 35  ? 14.344  14.624 4.203   1.00 13.79 ? 35  ALA L HB1  1 
ATOM   5168 H HB2  . ALA C 3 35  ? 14.879  14.314 2.740   1.00 13.79 ? 35  ALA L HB2  1 
ATOM   5169 H HB3  . ALA C 3 35  ? 13.365  14.744 2.957   1.00 13.79 ? 35  ALA L HB3  1 
ATOM   5170 N N    . TRP C 3 36  ? 13.047  12.716 5.804   1.00 11.74 ? 36  TRP L N    1 
ATOM   5171 C CA   . TRP C 3 36  ? 12.133  12.749 6.930   1.00 15.29 ? 36  TRP L CA   1 
ATOM   5172 C C    . TRP C 3 36  ? 12.497  13.926 7.819   1.00 12.17 ? 36  TRP L C    1 
ATOM   5173 O O    . TRP C 3 36  ? 13.694  14.146 8.079   1.00 12.48 ? 36  TRP L O    1 
ATOM   5174 C CB   . TRP C 3 36  ? 12.231  11.481 7.756   1.00 15.20 ? 36  TRP L CB   1 
ATOM   5175 C CG   . TRP C 3 36  ? 11.777  10.273 7.114   1.00 13.34 ? 36  TRP L CG   1 
ATOM   5176 C CD1  . TRP C 3 36  ? 12.510  9.398  6.363   1.00 16.02 ? 36  TRP L CD1  1 
ATOM   5177 C CD2  . TRP C 3 36  ? 10.458  9.761  7.158   1.00 13.09 ? 36  TRP L CD2  1 
ATOM   5178 N NE1  . TRP C 3 36  ? 11.705  8.399  5.905   1.00 15.49 ? 36  TRP L NE1  1 
ATOM   5179 C CE2  . TRP C 3 36  ? 10.454  8.561  6.426   1.00 14.65 ? 36  TRP L CE2  1 
ATOM   5180 C CE3  . TRP C 3 36  ? 9.279   10.174 7.777   1.00 13.70 ? 36  TRP L CE3  1 
ATOM   5181 C CZ2  . TRP C 3 36  ? 9.319   7.761  6.308   1.00 14.63 ? 36  TRP L CZ2  1 
ATOM   5182 C CZ3  . TRP C 3 36  ? 8.149   9.355  7.666   1.00 17.57 ? 36  TRP L CZ3  1 
ATOM   5183 C CH2  . TRP C 3 36  ? 8.180   8.185  6.912   1.00 16.66 ? 36  TRP L CH2  1 
ATOM   5184 H H    . TRP C 3 36  ? 13.876  12.702 6.032   1.00 14.15 ? 36  TRP L H    1 
ATOM   5185 H HA   . TRP C 3 36  ? 11.224  12.845 6.606   1.00 18.41 ? 36  TRP L HA   1 
ATOM   5186 H HB2  . TRP C 3 36  ? 13.162  11.346 7.995   1.00 18.30 ? 36  TRP L HB2  1 
ATOM   5187 H HB3  . TRP C 3 36  ? 11.697  11.598 8.557   1.00 18.30 ? 36  TRP L HB3  1 
ATOM   5188 H HD1  . TRP C 3 36  ? 13.421  9.473  6.191   1.00 19.28 ? 36  TRP L HD1  1 
ATOM   5189 H HE1  . TRP C 3 36  ? 11.946  7.767  5.373   1.00 18.65 ? 36  TRP L HE1  1 
ATOM   5190 H HE3  . TRP C 3 36  ? 9.244   10.974 8.252   1.00 16.50 ? 36  TRP L HE3  1 
ATOM   5191 H HZ2  . TRP C 3 36  ? 9.342   6.963  5.831   1.00 17.62 ? 36  TRP L HZ2  1 
ATOM   5192 H HZ3  . TRP C 3 36  ? 7.364   9.597  8.103   1.00 21.14 ? 36  TRP L HZ3  1 
ATOM   5193 H HH2  . TRP C 3 36  ? 7.403   7.682  6.820   1.00 20.05 ? 36  TRP L HH2  1 
ATOM   5194 N N    . TYR C 3 37  ? 11.475  14.643 8.295   1.00 12.43 ? 37  TYR L N    1 
ATOM   5195 C CA   . TYR C 3 37  ? 11.584  15.807 9.163   1.00 11.85 ? 37  TYR L CA   1 
ATOM   5196 C C    . TYR C 3 37  ? 10.786  15.589 10.434  1.00 12.86 ? 37  TYR L C    1 
ATOM   5197 O O    . TYR C 3 37  ? 9.715   15.009 10.391  1.00 12.72 ? 37  TYR L O    1 
ATOM   5198 C CB   . TYR C 3 37  ? 11.053  17.074 8.452   1.00 12.60 ? 37  TYR L CB   1 
ATOM   5199 C CG   . TYR C 3 37  ? 11.769  17.335 7.145   1.00 11.45 ? 37  TYR L CG   1 
ATOM   5200 C CD1  . TYR C 3 37  ? 11.356  16.732 5.995   1.00 10.26 ? 37  TYR L CD1  1 
ATOM   5201 C CD2  . TYR C 3 37  ? 12.893  18.167 7.080   1.00 11.83 ? 37  TYR L CD2  1 
ATOM   5202 C CE1  . TYR C 3 37  ? 12.018  16.923 4.802   1.00 12.99 ? 37  TYR L CE1  1 
ATOM   5203 C CE2  . TYR C 3 37  ? 13.557  18.378 5.859   1.00 10.38 ? 37  TYR L CE2  1 
ATOM   5204 C CZ   . TYR C 3 37  ? 13.107  17.760 4.749   1.00 10.19 ? 37  TYR L CZ   1 
ATOM   5205 O OH   . TYR C 3 37  ? 13.749  17.914 3.564   1.00 11.17 ? 37  TYR L OH   1 
ATOM   5206 H H    . TYR C 3 37  ? 10.655  14.457 8.114   1.00 14.98 ? 37  TYR L H    1 
ATOM   5207 H HA   . TYR C 3 37  ? 12.514  15.940 9.402   1.00 14.28 ? 37  TYR L HA   1 
ATOM   5208 H HB2  . TYR C 3 37  ? 10.108  16.961 8.262   1.00 15.18 ? 37  TYR L HB2  1 
ATOM   5209 H HB3  . TYR C 3 37  ? 11.186  17.843 9.029   1.00 15.18 ? 37  TYR L HB3  1 
ATOM   5210 H HD1  . TYR C 3 37  ? 10.608  16.179 6.016   1.00 12.38 ? 37  TYR L HD1  1 
ATOM   5211 H HD2  . TYR C 3 37  ? 13.204  18.583 7.851   1.00 14.26 ? 37  TYR L HD2  1 
ATOM   5212 H HE1  . TYR C 3 37  ? 11.730  16.485 4.034   1.00 15.65 ? 37  TYR L HE1  1 
ATOM   5213 H HE2  . TYR C 3 37  ? 14.299  18.938 5.817   1.00 12.52 ? 37  TYR L HE2  1 
ATOM   5214 H HH   . TYR C 3 37  ? 14.553  18.117 3.697   1.00 13.47 ? 37  TYR L HH   1 
ATOM   5215 N N    . GLN C 3 38  ? 11.287  16.109 11.555  1.00 12.28 ? 38  GLN L N    1 
ATOM   5216 C CA   . GLN C 3 38  ? 10.553  16.196 12.803  1.00 14.85 ? 38  GLN L CA   1 
ATOM   5217 C C    . GLN C 3 38  ? 10.054  17.614 12.993  1.00 12.96 ? 38  GLN L C    1 
ATOM   5218 O O    . GLN C 3 38  ? 10.790  18.573 12.748  1.00 14.74 ? 38  GLN L O    1 
ATOM   5219 C CB   . GLN C 3 38  ? 11.486  15.835 13.960  1.00 12.47 ? 38  GLN L CB   1 
ATOM   5220 C CG   . GLN C 3 38  ? 10.853  15.745 15.298  1.00 14.83 ? 38  GLN L CG   1 
ATOM   5221 C CD   . GLN C 3 38  ? 11.916  15.616 16.404  1.00 18.72 ? 38  GLN L CD   1 
ATOM   5222 O OE1  . GLN C 3 38  ? 12.720  16.513 16.599  1.00 14.06 ? 38  GLN L OE1  1 
ATOM   5223 N NE2  . GLN C 3 38  ? 11.992  14.441 17.047  1.00 14.58 ? 38  GLN L NE2  1 
ATOM   5224 H H    . GLN C 3 38  ? 12.083  16.430 11.613  1.00 14.80 ? 38  GLN L H    1 
ATOM   5225 H HA   . GLN C 3 38  ? 9.792   15.594 12.797  1.00 17.88 ? 38  GLN L HA   1 
ATOM   5226 H HB2  . GLN C 3 38  ? 11.882  14.970 13.772  1.00 15.03 ? 38  GLN L HB2  1 
ATOM   5227 H HB3  . GLN C 3 38  ? 12.178  16.512 14.015  1.00 15.03 ? 38  GLN L HB3  1 
ATOM   5228 H HG2  . GLN C 3 38  ? 10.334  16.548 15.463  1.00 17.86 ? 38  GLN L HG2  1 
ATOM   5229 H HG3  . GLN C 3 38  ? 10.278  14.965 15.331  1.00 17.86 ? 38  GLN L HG3  1 
ATOM   5230 H HE21 . GLN C 3 38  ? 11.460  13.799 16.835  1.00 17.55 ? 38  GLN L HE21 1 
ATOM   5231 H HE22 . GLN C 3 38  ? 12.573  14.329 17.671  1.00 17.55 ? 38  GLN L HE22 1 
ATOM   5232 N N    . GLN C 3 39  ? 8.859   17.735 13.553  1.00 9.97  ? 39  GLN L N    1 
ATOM   5233 C CA   . GLN C 3 39  ? 8.370   19.039 13.957  1.00 12.06 ? 39  GLN L CA   1 
ATOM   5234 C C    . GLN C 3 39  ? 7.617   18.978 15.271  1.00 15.52 ? 39  GLN L C    1 
ATOM   5235 O O    . GLN C 3 39  ? 6.635   18.246 15.387  1.00 16.28 ? 39  GLN L O    1 
ATOM   5236 C CB   . GLN C 3 39  ? 7.445   19.642 12.889  1.00 11.06 ? 39  GLN L CB   1 
ATOM   5237 C CG   . GLN C 3 39  ? 7.201   21.121 13.148  1.00 13.51 ? 39  GLN L CG   1 
ATOM   5238 C CD   . GLN C 3 39  ? 6.272   21.751 12.152  1.00 15.97 ? 39  GLN L CD   1 
ATOM   5239 O OE1  . GLN C 3 39  ? 5.333   21.131 11.659  1.00 15.08 ? 39  GLN L OE1  1 
ATOM   5240 N NE2  . GLN C 3 39  ? 6.581   22.982 11.783  1.00 16.04 ? 39  GLN L NE2  1 
ATOM   5241 H H    . GLN C 3 39  ? 8.320   17.083 13.706  1.00 12.02 ? 39  GLN L H    1 
ATOM   5242 H HA   . GLN C 3 39  ? 9.145   19.605 14.092  1.00 14.54 ? 39  GLN L HA   1 
ATOM   5243 H HB2  . GLN C 3 39  ? 7.856   19.547 12.016  1.00 13.34 ? 39  GLN L HB2  1 
ATOM   5244 H HB3  . GLN C 3 39  ? 6.591   19.183 12.906  1.00 13.34 ? 39  GLN L HB3  1 
ATOM   5245 H HG2  . GLN C 3 39  ? 6.809   21.226 14.029  1.00 16.27 ? 39  GLN L HG2  1 
ATOM   5246 H HG3  . GLN C 3 39  ? 8.048   21.592 13.104  1.00 16.27 ? 39  GLN L HG3  1 
ATOM   5247 H HE21 . GLN C 3 39  ? 7.275   23.369 12.111  1.00 19.31 ? 39  GLN L HE21 1 
ATOM   5248 H HE22 . GLN C 3 39  ? 6.087   23.397 11.214  1.00 19.31 ? 39  GLN L HE22 1 
ATOM   5249 N N    . LYS C 3 40  ? 8.031   19.809 16.223  1.00 18.29 ? 40  LYS L N    1 
ATOM   5250 C CA   . LYS C 3 40  ? 7.385   20.042 17.519  1.00 20.61 ? 40  LYS L CA   1 
ATOM   5251 C C    . LYS C 3 40  ? 6.542   21.334 17.489  1.00 25.42 ? 40  LYS L C    1 
ATOM   5252 O O    . LYS C 3 40  ? 6.758   22.212 16.652  1.00 20.66 ? 40  LYS L O    1 
ATOM   5253 C CB   . LYS C 3 40  ? 8.476   20.126 18.587  1.00 24.67 ? 40  LYS L CB   1 
ATOM   5254 C CG   . LYS C 3 40  ? 8.995   18.737 18.841  1.00 21.80 ? 40  LYS L CG   1 
ATOM   5255 C CD   . LYS C 3 40  ? 10.460  18.673 19.211  1.00 27.97 ? 40  LYS L CD   1 
ATOM   5256 C CE   . LYS C 3 40  ? 10.721  17.626 20.265  1.00 29.48 ? 40  LYS L CE   1 
ATOM   5257 N NZ   . LYS C 3 40  ? 11.858  17.946 21.130  1.00 27.69 ? 40  LYS L NZ   1 
ATOM   5258 H H    . LYS C 3 40  ? 8.740   20.289 16.139  1.00 22.01 ? 40  LYS L H    1 
ATOM   5259 H HA   . LYS C 3 40  ? 6.778   19.319 17.744  1.00 24.79 ? 40  LYS L HA   1 
ATOM   5260 H HB2  . LYS C 3 40  ? 9.203   20.687 18.276  1.00 29.66 ? 40  LYS L HB2  1 
ATOM   5261 H HB3  . LYS C 3 40  ? 8.108   20.485 19.410  1.00 29.66 ? 40  LYS L HB3  1 
ATOM   5262 H HG2  . LYS C 3 40  ? 8.492   18.347 19.574  1.00 26.22 ? 40  LYS L HG2  1 
ATOM   5263 H HG3  . LYS C 3 40  ? 8.874   18.209 18.037  1.00 26.22 ? 40  LYS L HG3  1 
ATOM   5264 H HD2  . LYS C 3 40  ? 10.980  18.448 18.423  1.00 33.62 ? 40  LYS L HD2  1 
ATOM   5265 H HD3  . LYS C 3 40  ? 10.741  19.533 19.560  1.00 33.62 ? 40  LYS L HD3  1 
ATOM   5266 H HE2  . LYS C 3 40  ? 9.934   17.542 20.826  1.00 35.44 ? 40  LYS L HE2  1 
ATOM   5267 H HE3  . LYS C 3 40  ? 10.909  16.781 19.828  1.00 35.44 ? 40  LYS L HE3  1 
ATOM   5268 H HZ1  . LYS C 3 40  ? 11.935  17.333 21.771  1.00 33.28 ? 40  LYS L HZ1  1 
ATOM   5269 H HZ2  . LYS C 3 40  ? 12.609  17.962 20.653  1.00 33.28 ? 40  LYS L HZ2  1 
ATOM   5270 H HZ3  . LYS C 3 40  ? 11.739  18.744 21.507  1.00 33.28 ? 40  LYS L HZ3  1 
ATOM   5271 N N    . PRO C 3 41  ? 5.546   21.490 18.358  1.00 26.69 ? 41  PRO L N    1 
ATOM   5272 C CA   . PRO C 3 41  ? 4.679   22.675 18.266  1.00 27.67 ? 41  PRO L CA   1 
ATOM   5273 C C    . PRO C 3 41  ? 5.474   23.960 18.396  1.00 23.18 ? 41  PRO L C    1 
ATOM   5274 O O    . PRO C 3 41  ? 6.389   24.076 19.210  1.00 25.70 ? 41  PRO L O    1 
ATOM   5275 C CB   . PRO C 3 41  ? 3.710   22.485 19.439  1.00 30.05 ? 41  PRO L CB   1 
ATOM   5276 C CG   . PRO C 3 41  ? 3.597   20.978 19.560  1.00 30.80 ? 41  PRO L CG   1 
ATOM   5277 C CD   . PRO C 3 41  ? 4.982   20.474 19.247  1.00 24.96 ? 41  PRO L CD   1 
ATOM   5278 H HA   . PRO C 3 41  ? 4.190   22.682 17.429  1.00 33.27 ? 41  PRO L HA   1 
ATOM   5279 H HB2  . PRO C 3 41  ? 4.077   22.878 20.246  1.00 36.12 ? 41  PRO L HB2  1 
ATOM   5280 H HB3  . PRO C 3 41  ? 2.852   22.888 19.234  1.00 36.12 ? 41  PRO L HB3  1 
ATOM   5281 H HG2  . PRO C 3 41  ? 3.332   20.736 20.462  1.00 37.03 ? 41  PRO L HG2  1 
ATOM   5282 H HG3  . PRO C 3 41  ? 2.949   20.640 18.922  1.00 37.03 ? 41  PRO L HG3  1 
ATOM   5283 H HD2  . PRO C 3 41  ? 5.510   20.399 20.058  1.00 30.01 ? 41  PRO L HD2  1 
ATOM   5284 H HD3  . PRO C 3 41  ? 4.939   19.614 18.799  1.00 30.01 ? 41  PRO L HD3  1 
ATOM   5285 N N    . GLY C 3 42  ? 5.143   24.915 17.548  1.00 26.18 ? 42  GLY L N    1 
ATOM   5286 C CA   . GLY C 3 42  ? 5.814   26.199 17.578  1.00 28.75 ? 42  GLY L CA   1 
ATOM   5287 C C    . GLY C 3 42  ? 7.254   26.227 17.104  1.00 28.79 ? 42  GLY L C    1 
ATOM   5288 O O    . GLY C 3 42  ? 7.928   27.254 17.263  1.00 27.53 ? 42  GLY L O    1 
ATOM   5289 H H    . GLY C 3 42  ? 4.534   24.846 16.945  1.00 31.47 ? 42  GLY L H    1 
ATOM   5290 H HA2  . GLY C 3 42  ? 5.315   26.815 17.020  1.00 34.56 ? 42  GLY L HA2  1 
ATOM   5291 H HA3  . GLY C 3 42  ? 5.805   26.523 18.492  1.00 34.56 ? 42  GLY L HA3  1 
ATOM   5292 N N    . GLN C 3 43  ? 7.755   25.150 16.509  1.00 22.75 ? 43  GLN L N    1 
ATOM   5293 C CA   . GLN C 3 43  ? 9.127   25.105 16.047  1.00 20.36 ? 43  GLN L CA   1 
ATOM   5294 C C    . GLN C 3 43  ? 9.173   24.780 14.564  1.00 19.02 ? 43  GLN L C    1 
ATOM   5295 O O    . GLN C 3 43  ? 8.204   24.292 13.990  1.00 18.55 ? 43  GLN L O    1 
ATOM   5296 C CB   . GLN C 3 43  ? 9.964   24.065 16.776  1.00 25.74 ? 43  GLN L CB   1 
ATOM   5297 C CG   . GLN C 3 43  ? 10.259  24.321 18.239  1.00 26.76 ? 43  GLN L CG   1 
ATOM   5298 C CD   . GLN C 3 43  ? 11.040  23.171 18.829  1.00 27.83 ? 43  GLN L CD   1 
ATOM   5299 O OE1  . GLN C 3 43  ? 11.659  22.392 18.098  1.00 36.45 ? 43  GLN L OE1  1 
ATOM   5300 N NE2  . GLN C 3 43  ? 11.040  23.059 20.140  1.00 36.80 ? 43  GLN L NE2  1 
ATOM   5301 H H    . GLN C 3 43  ? 7.310   24.429 16.362  1.00 27.36 ? 43  GLN L H    1 
ATOM   5302 H HA   . GLN C 3 43  ? 9.512   25.981 16.206  1.00 24.49 ? 43  GLN L HA   1 
ATOM   5303 H HB2  . GLN C 3 43  ? 9.496   23.217 16.727  1.00 30.95 ? 43  GLN L HB2  1 
ATOM   5304 H HB3  . GLN C 3 43  ? 10.820  23.999 16.323  1.00 30.95 ? 43  GLN L HB3  1 
ATOM   5305 H HG2  . GLN C 3 43  ? 10.786  25.130 18.327  1.00 32.18 ? 43  GLN L HG2  1 
ATOM   5306 H HG3  . GLN C 3 43  ? 9.426   24.412 18.727  1.00 32.18 ? 43  GLN L HG3  1 
ATOM   5307 H HE21 . GLN C 3 43  ? 10.608  23.627 20.620  1.00 44.22 ? 43  GLN L HE21 1 
ATOM   5308 H HE22 . GLN C 3 43  ? 11.472  22.418 20.517  1.00 44.22 ? 43  GLN L HE22 1 
ATOM   5309 N N    . ALA C 3 44  ? 10.300  25.106 13.942  1.00 19.43 ? 44  ALA L N    1 
ATOM   5310 C CA   . ALA C 3 44  ? 10.467  24.768 12.538  1.00 18.12 ? 44  ALA L CA   1 
ATOM   5311 C C    . ALA C 3 44  ? 10.726  23.265 12.370  1.00 18.09 ? 44  ALA L C    1 
ATOM   5312 O O    . ALA C 3 44  ? 11.194  22.599 13.290  1.00 18.91 ? 44  ALA L O    1 
ATOM   5313 C CB   . ALA C 3 44  ? 11.634  25.542 11.926  1.00 21.57 ? 44  ALA L CB   1 
ATOM   5314 H H    . ALA C 3 44  ? 10.965  25.514 14.303  1.00 23.37 ? 44  ALA L H    1 
ATOM   5315 H HA   . ALA C 3 44  ? 9.655   25.006 12.065  1.00 21.81 ? 44  ALA L HA   1 
ATOM   5316 H HB1  . ALA C 3 44  ? 11.690  25.333 10.980  1.00 25.94 ? 44  ALA L HB1  1 
ATOM   5317 H HB2  . ALA C 3 44  ? 11.481  26.492 12.046  1.00 25.94 ? 44  ALA L HB2  1 
ATOM   5318 H HB3  . ALA C 3 44  ? 12.455  25.280 12.371  1.00 25.94 ? 44  ALA L HB3  1 
ATOM   5319 N N    . PRO C 3 45  ? 10.489  22.723 11.178  1.00 19.01 ? 45  PRO L N    1 
ATOM   5320 C CA   . PRO C 3 45  ? 10.890  21.342 10.909  1.00 16.83 ? 45  PRO L CA   1 
ATOM   5321 C C    . PRO C 3 45  ? 12.382  21.157 11.032  1.00 15.83 ? 45  PRO L C    1 
ATOM   5322 O O    . PRO C 3 45  ? 13.180  22.078 10.777  1.00 16.22 ? 45  PRO L O    1 
ATOM   5323 C CB   . PRO C 3 45  ? 10.465  21.121 9.463   1.00 16.25 ? 45  PRO L CB   1 
ATOM   5324 C CG   . PRO C 3 45  ? 9.364   22.126 9.224   1.00 21.44 ? 45  PRO L CG   1 
ATOM   5325 C CD   . PRO C 3 45  ? 9.750   23.318 10.053  1.00 17.64 ? 45  PRO L CD   1 
ATOM   5326 H HA   . PRO C 3 45  ? 10.420  20.739 11.507  1.00 20.26 ? 45  PRO L HA   1 
ATOM   5327 H HB2  . PRO C 3 45  ? 11.216  21.280 8.870   1.00 19.57 ? 45  PRO L HB2  1 
ATOM   5328 H HB3  . PRO C 3 45  ? 10.139  20.214 9.350   1.00 19.57 ? 45  PRO L HB3  1 
ATOM   5329 H HG2  . PRO C 3 45  ? 9.323   22.356 8.282   1.00 25.79 ? 45  PRO L HG2  1 
ATOM   5330 H HG3  . PRO C 3 45  ? 8.513   21.762 9.514   1.00 25.79 ? 45  PRO L HG3  1 
ATOM   5331 H HD2  . PRO C 3 45  ? 10.318  23.921 9.548   1.00 21.23 ? 45  PRO L HD2  1 
ATOM   5332 H HD3  . PRO C 3 45  ? 8.963   23.789 10.368  1.00 21.23 ? 45  PRO L HD3  1 
ATOM   5333 N N    . ARG C 3 46  ? 12.755  19.931 11.384  1.00 12.20 ? 46  ARG L N    1 
ATOM   5334 C CA   . ARG C 3 46  ? 14.158  19.540 11.509  1.00 11.94 ? 46  ARG L CA   1 
ATOM   5335 C C    . ARG C 3 46  ? 14.426  18.309 10.643  1.00 12.00 ? 46  ARG L C    1 
ATOM   5336 O O    . ARG C 3 46  ? 13.748  17.295 10.770  1.00 14.10 ? 46  ARG L O    1 
ATOM   5337 C CB   . ARG C 3 46  ? 14.551  19.221 12.984  1.00 16.97 ? 46  ARG L CB   1 
ATOM   5338 H H    . ARG C 3 46  ? 12.204  19.295 11.559  1.00 14.70 ? 46  ARG L H    1 
ATOM   5339 H HA   . ARG C 3 46  ? 14.706  20.277 11.196  1.00 14.39 ? 46  ARG L HA   1 
ATOM   5340 N N    . LEU C 3 47  ? 15.427  18.385 9.781   1.00 10.80 ? 47  LEU L N    1 
ATOM   5341 C CA   . LEU C 3 47  ? 15.825  17.210 9.000   1.00 11.61 ? 47  LEU L CA   1 
ATOM   5342 C C    . LEU C 3 47  ? 16.386  16.110 9.893   1.00 14.23 ? 47  LEU L C    1 
ATOM   5343 O O    . LEU C 3 47  ? 17.302  16.354 10.680  1.00 14.89 ? 47  LEU L O    1 
ATOM   5344 C CB   . LEU C 3 47  ? 16.888  17.575 7.950   1.00 14.77 ? 47  LEU L CB   1 
ATOM   5345 C CG   . LEU C 3 47  ? 17.349  16.490 6.948   1.00 12.66 ? 47  LEU L CG   1 
ATOM   5346 C CD1  . LEU C 3 47  ? 16.128  15.948 6.179   1.00 14.69 ? 47  LEU L CD1  1 
ATOM   5347 C CD2  . LEU C 3 47  ? 18.490  16.987 6.037   1.00 14.63 ? 47  LEU L CD2  1 
ATOM   5348 H H    . LEU C 3 47  ? 15.890  19.093 9.626   1.00 13.03 ? 47  LEU L H    1 
ATOM   5349 H HA   . LEU C 3 47  ? 15.031  16.879 8.551   1.00 13.99 ? 47  LEU L HA   1 
ATOM   5350 H HB2  . LEU C 3 47  ? 16.534  18.306 7.420   1.00 17.79 ? 47  LEU L HB2  1 
ATOM   5351 H HB3  . LEU C 3 47  ? 17.681  17.864 8.427   1.00 17.79 ? 47  LEU L HB3  1 
ATOM   5352 H HG   . LEU C 3 47  ? 17.739  15.742 7.427   1.00 15.25 ? 47  LEU L HG   1 
ATOM   5353 H HD11 . LEU C 3 47  ? 16.426  15.276 5.547   1.00 17.69 ? 47  LEU L HD11 1 
ATOM   5354 H HD12 . LEU C 3 47  ? 15.506  15.555 6.811   1.00 17.69 ? 47  LEU L HD12 1 
ATOM   5355 H HD13 . LEU C 3 47  ? 15.702  16.681 5.707   1.00 17.69 ? 47  LEU L HD13 1 
ATOM   5356 H HD21 . LEU C 3 47  ? 18.855  16.233 5.547   1.00 17.62 ? 47  LEU L HD21 1 
ATOM   5357 H HD22 . LEU C 3 47  ? 18.136  17.644 5.416   1.00 17.62 ? 47  LEU L HD22 1 
ATOM   5358 H HD23 . LEU C 3 47  ? 19.180  17.390 6.586   1.00 17.62 ? 47  LEU L HD23 1 
ATOM   5359 N N    . LEU C 3 48  ? 15.871  14.884 9.741   1.00 15.27 ? 48  LEU L N    1 
ATOM   5360 C CA   . LEU C 3 48  ? 16.349  13.684 10.423  1.00 16.28 ? 48  LEU L CA   1 
ATOM   5361 C C    . LEU C 3 48  ? 17.126  12.760 9.508   1.00 15.21 ? 48  LEU L C    1 
ATOM   5362 O O    . LEU C 3 48  ? 18.261  12.366 9.816   1.00 15.25 ? 48  LEU L O    1 
ATOM   5363 C CB   . LEU C 3 48  ? 15.139  12.919 10.958  1.00 12.61 ? 48  LEU L CB   1 
ATOM   5364 C CG   . LEU C 3 48  ? 14.302  13.616 12.015  1.00 13.92 ? 48  LEU L CG   1 
ATOM   5365 C CD1  . LEU C 3 48  ? 13.086  12.747 12.243  1.00 16.15 ? 48  LEU L CD1  1 
ATOM   5366 C CD2  . LEU C 3 48  ? 15.059  13.870 13.260  1.00 18.25 ? 48  LEU L CD2  1 
ATOM   5367 H H    . LEU C 3 48  ? 15.209  14.718 9.218   1.00 18.38 ? 48  LEU L H    1 
ATOM   5368 H HA   . LEU C 3 48  ? 16.929  13.944 11.155  1.00 19.59 ? 48  LEU L HA   1 
ATOM   5369 H HB2  . LEU C 3 48  ? 14.551  12.728 10.211  1.00 15.19 ? 48  LEU L HB2  1 
ATOM   5370 H HB3  . LEU C 3 48  ? 15.458  12.091 11.350  1.00 15.19 ? 48  LEU L HB3  1 
ATOM   5371 H HG   . LEU C 3 48  ? 14.033  14.500 11.720  1.00 16.76 ? 48  LEU L HG   1 
ATOM   5372 H HD11 . LEU C 3 48  ? 12.965  12.617 13.197  1.00 19.44 ? 48  LEU L HD11 1 
ATOM   5373 H HD12 . LEU C 3 48  ? 12.308  13.187 11.867  1.00 19.44 ? 48  LEU L HD12 1 
ATOM   5374 H HD13 . LEU C 3 48  ? 13.224  11.891 11.808  1.00 19.44 ? 48  LEU L HD13 1 
ATOM   5375 H HD21 . LEU C 3 48  ? 14.472  14.296 13.904  1.00 21.96 ? 48  LEU L HD21 1 
ATOM   5376 H HD22 . LEU C 3 48  ? 15.380  13.026 13.612  1.00 21.96 ? 48  LEU L HD22 1 
ATOM   5377 H HD23 . LEU C 3 48  ? 15.809  14.452 13.060  1.00 21.96 ? 48  LEU L HD23 1 
ATOM   5378 N N    . ILE C 3 49  ? 16.514  12.397 8.373   1.00 12.66 ? 49  ILE L N    1 
ATOM   5379 C CA   . ILE C 3 49  ? 17.056  11.402 7.472   1.00 15.56 ? 49  ILE L CA   1 
ATOM   5380 C C    . ILE C 3 49  ? 16.847  11.862 6.033   1.00 16.36 ? 49  ILE L C    1 
ATOM   5381 O O    . ILE C 3 49  ? 15.886  12.565 5.712   1.00 14.10 ? 49  ILE L O    1 
ATOM   5382 C CB   . ILE C 3 49  ? 16.399  10.020 7.727   1.00 16.83 ? 49  ILE L CB   1 
ATOM   5383 C CG1  . ILE C 3 49  ? 16.921  9.503  9.078   1.00 21.93 ? 49  ILE L CG1  1 
ATOM   5384 C CG2  . ILE C 3 49  ? 16.626  9.069  6.573   1.00 17.77 ? 49  ILE L CG2  1 
ATOM   5385 C CD1  . ILE C 3 49  ? 16.946  8.092  9.312   1.00 32.49 ? 49  ILE L CD1  1 
ATOM   5386 H H    . ILE C 3 49  ? 15.766  12.728 8.107   1.00 15.25 ? 49  ILE L H    1 
ATOM   5387 H HA   . ILE C 3 49  ? 18.014  11.319 7.604   1.00 18.74 ? 49  ILE L HA   1 
ATOM   5388 H HB   . ILE C 3 49  ? 15.434  10.103 7.779   1.00 20.26 ? 49  ILE L HB   1 
ATOM   5389 H HG12 . ILE C 3 49  ? 17.835  9.813  9.177   1.00 26.38 ? 49  ILE L HG12 1 
ATOM   5390 H HG13 . ILE C 3 49  ? 16.364  9.886  9.773   1.00 26.38 ? 49  ILE L HG13 1 
ATOM   5391 H HG21 . ILE C 3 49  ? 16.200  8.221  6.776   1.00 21.38 ? 49  ILE L HG21 1 
ATOM   5392 H HG22 . ILE C 3 49  ? 16.239  9.450  5.770   1.00 21.38 ? 49  ILE L HG22 1 
ATOM   5393 H HG23 . ILE C 3 49  ? 17.579  8.940  6.453   1.00 21.38 ? 49  ILE L HG23 1 
ATOM   5394 H HD11 . ILE C 3 49  ? 17.297  7.925  10.200  1.00 39.05 ? 49  ILE L HD11 1 
ATOM   5395 H HD12 . ILE C 3 49  ? 16.043  7.745  9.242   1.00 39.05 ? 49  ILE L HD12 1 
ATOM   5396 H HD13 . ILE C 3 49  ? 17.514  7.672  8.647   1.00 39.05 ? 49  ILE L HD13 1 
ATOM   5397 N N    . TYR C 3 50  ? 17.801  11.510 5.182   1.00 16.03 ? 50  TYR L N    1 
ATOM   5398 C CA   . TYR C 3 50  ? 17.766  11.841 3.769   1.00 14.68 ? 50  TYR L CA   1 
ATOM   5399 C C    . TYR C 3 50  ? 18.372  10.673 3.002   1.00 17.22 ? 50  TYR L C    1 
ATOM   5400 O O    . TYR C 3 50  ? 19.059  9.808  3.572   1.00 16.67 ? 50  TYR L O    1 
ATOM   5401 C CB   . TYR C 3 50  ? 18.525  13.172 3.469   1.00 15.40 ? 50  TYR L CB   1 
ATOM   5402 C CG   . TYR C 3 50  ? 19.998  13.096 3.726   1.00 16.31 ? 50  TYR L CG   1 
ATOM   5403 C CD1  . TYR C 3 50  ? 20.518  13.337 4.991   1.00 17.64 ? 50  TYR L CD1  1 
ATOM   5404 C CD2  . TYR C 3 50  ? 20.872  12.731 2.719   1.00 19.64 ? 50  TYR L CD2  1 
ATOM   5405 C CE1  . TYR C 3 50  ? 21.902  13.226 5.241   1.00 23.95 ? 50  TYR L CE1  1 
ATOM   5406 C CE2  . TYR C 3 50  ? 22.251  12.626 2.952   1.00 23.99 ? 50  TYR L CE2  1 
ATOM   5407 C CZ   . TYR C 3 50  ? 22.750  12.873 4.214   1.00 26.04 ? 50  TYR L CZ   1 
ATOM   5408 O OH   . TYR C 3 50  ? 24.101  12.748 4.436   1.00 27.65 ? 50  TYR L OH   1 
ATOM   5409 H H    . TYR C 3 50  ? 18.501  11.064 5.408   1.00 19.29 ? 50  TYR L H    1 
ATOM   5410 H HA   . TYR C 3 50  ? 16.851  11.963 3.470   1.00 17.67 ? 50  TYR L HA   1 
ATOM   5411 H HB2  . TYR C 3 50  ? 18.399  13.400 2.535   1.00 18.55 ? 50  TYR L HB2  1 
ATOM   5412 H HB3  . TYR C 3 50  ? 18.162  13.873 4.034   1.00 18.55 ? 50  TYR L HB3  1 
ATOM   5413 H HD1  . TYR C 3 50  ? 19.945  13.576 5.684   1.00 21.23 ? 50  TYR L HD1  1 
ATOM   5414 H HD2  . TYR C 3 50  ? 20.539  12.552 1.869   1.00 23.63 ? 50  TYR L HD2  1 
ATOM   5415 H HE1  . TYR C 3 50  ? 22.239  13.389 6.092   1.00 28.80 ? 50  TYR L HE1  1 
ATOM   5416 H HE2  . TYR C 3 50  ? 22.825  12.390 2.259   1.00 28.85 ? 50  TYR L HE2  1 
ATOM   5417 H HH   . TYR C 3 50  ? 24.261  12.784 5.259   1.00 33.24 ? 50  TYR L HH   1 
ATOM   5418 N N    . GLY C 3 51  ? 18.061  10.617 1.708   1.00 16.70 ? 51  GLY L N    1 
ATOM   5419 C CA   . GLY C 3 51  ? 18.531  9.530  0.864   1.00 14.85 ? 51  GLY L CA   1 
ATOM   5420 C C    . GLY C 3 51  ? 17.983  8.221  1.358   1.00 18.32 ? 51  GLY L C    1 
ATOM   5421 O O    . GLY C 3 51  ? 18.640  7.187  1.227   1.00 19.31 ? 51  GLY L O    1 
ATOM   5422 H H    . GLY C 3 51  ? 17.579  11.198 1.296   1.00 20.10 ? 51  GLY L H    1 
ATOM   5423 H HA2  . GLY C 3 51  ? 18.236  9.671  -0.050  1.00 17.88 ? 51  GLY L HA2  1 
ATOM   5424 H HA3  . GLY C 3 51  ? 19.500  9.494  0.881   1.00 17.88 ? 51  GLY L HA3  1 
ATOM   5425 N N    . ALA C 3 52  ? 16.816  8.273  2.023   1.00 17.10 ? 52  ALA L N    1 
ATOM   5426 C CA   . ALA C 3 52  ? 16.122  7.119  2.591   1.00 18.81 ? 52  ALA L CA   1 
ATOM   5427 C C    . ALA C 3 52  ? 16.772  6.649  3.903   1.00 20.39 ? 52  ALA L C    1 
ATOM   5428 O O    . ALA C 3 52  ? 16.050  6.291  4.834   1.00 19.64 ? 52  ALA L O    1 
ATOM   5429 C CB   . ALA C 3 52  ? 16.050  5.983  1.560   1.00 15.76 ? 52  ALA L CB   1 
ATOM   5430 H H    . ALA C 3 52  ? 16.388  9.006  2.163   1.00 20.58 ? 52  ALA L H    1 
ATOM   5431 N N    . PHE C 3 53  ? 18.133  6.637  4.006   1.00 21.45 ? 53  PHE L N    1 
ATOM   5432 C CA   . PHE C 3 53  ? 18.779  5.964  5.137   1.00 21.36 ? 53  PHE L CA   1 
ATOM   5433 C C    . PHE C 3 53  ? 19.913  6.748  5.792   1.00 23.72 ? 53  PHE L C    1 
ATOM   5434 O O    . PHE C 3 53  ? 20.475  6.271  6.775   1.00 23.86 ? 53  PHE L O    1 
ATOM   5435 C CB   . PHE C 3 53  ? 19.352  4.581  4.708   1.00 23.92 ? 53  PHE L CB   1 
ATOM   5436 C CG   . PHE C 3 53  ? 20.440  4.665  3.684   1.00 25.89 ? 53  PHE L CG   1 
ATOM   5437 C CD1  . PHE C 3 53  ? 20.151  4.641  2.335   1.00 33.34 ? 53  PHE L CD1  1 
ATOM   5438 C CD2  . PHE C 3 53  ? 21.772  4.769  4.086   1.00 35.67 ? 53  PHE L CD2  1 
ATOM   5439 C CE1  . PHE C 3 53  ? 21.175  4.729  1.393   1.00 38.06 ? 53  PHE L CE1  1 
ATOM   5440 C CE2  . PHE C 3 53  ? 22.793  4.853  3.161   1.00 34.79 ? 53  PHE L CE2  1 
ATOM   5441 C CZ   . PHE C 3 53  ? 22.499  4.838  1.813   1.00 38.45 ? 53  PHE L CZ   1 
ATOM   5442 H H    . PHE C 3 53  ? 18.672  7.003  3.445   1.00 25.80 ? 53  PHE L H    1 
ATOM   5443 H HA   . PHE C 3 53  ? 18.089  5.829  5.805   1.00 25.70 ? 53  PHE L HA   1 
ATOM   5444 H HB2  . PHE C 3 53  ? 19.717  4.140  5.491   1.00 28.76 ? 53  PHE L HB2  1 
ATOM   5445 H HB3  . PHE C 3 53  ? 18.633  4.050  4.332   1.00 28.76 ? 53  PHE L HB3  1 
ATOM   5446 H HD1  . PHE C 3 53  ? 19.268  4.566  2.052   1.00 40.06 ? 53  PHE L HD1  1 
ATOM   5447 H HD2  . PHE C 3 53  ? 21.976  4.783  4.993   1.00 42.87 ? 53  PHE L HD2  1 
ATOM   5448 H HE1  . PHE C 3 53  ? 20.974  4.715  0.485   1.00 45.73 ? 53  PHE L HE1  1 
ATOM   5449 H HE2  . PHE C 3 53  ? 23.676  4.919  3.445   1.00 41.81 ? 53  PHE L HE2  1 
ATOM   5450 H HZ   . PHE C 3 53  ? 23.183  4.900  1.186   1.00 46.20 ? 53  PHE L HZ   1 
ATOM   5451 N N    . SER C 3 54  ? 20.283  7.920  5.290   1.00 18.48 ? 54  SER L N    1 
ATOM   5452 C CA   . SER C 3 54  ? 21.373  8.680  5.875   1.00 16.39 ? 54  SER L CA   1 
ATOM   5453 C C    . SER C 3 54  ? 20.861  9.604  6.980   1.00 20.38 ? 54  SER L C    1 
ATOM   5454 O O    . SER C 3 54  ? 19.897  10.347 6.787   1.00 17.84 ? 54  SER L O    1 
ATOM   5455 C CB   . SER C 3 54  ? 22.091  9.475  4.774   1.00 20.13 ? 54  SER L CB   1 
ATOM   5456 O OG   . SER C 3 54  ? 22.703  8.576  3.842   1.00 24.12 ? 54  SER L OG   1 
ATOM   5457 H H    . SER C 3 54  ? 19.916  8.295  4.608   1.00 22.24 ? 54  SER L H    1 
ATOM   5458 H HA   . SER C 3 54  ? 22.008  8.076  6.291   1.00 19.73 ? 54  SER L HA   1 
ATOM   5459 H HB2  . SER C 3 54  ? 21.446  10.029 4.307   1.00 24.21 ? 54  SER L HB2  1 
ATOM   5460 H HB3  . SER C 3 54  ? 22.776  10.032 5.177   1.00 24.21 ? 54  SER L HB3  1 
ATOM   5461 H HG   . SER C 3 54  ? 22.901  8.985  3.135   1.00 29.00 ? 54  SER L HG   1 
ATOM   5462 N N    . ARG C 3 55  ? 21.542  9.604  8.121   1.00 20.87 ? 55  ARG L N    1 
ATOM   5463 C CA   . ARG C 3 55  ? 21.206  10.521 9.186   1.00 20.53 ? 55  ARG L CA   1 
ATOM   5464 C C    . ARG C 3 55  ? 21.844  11.879 8.943   1.00 21.21 ? 55  ARG L C    1 
ATOM   5465 O O    . ARG C 3 55  ? 23.013  11.970 8.555   1.00 25.86 ? 55  ARG L O    1 
ATOM   5466 C CB   . ARG C 3 55  ? 21.676  9.963  10.535  1.00 24.76 ? 55  ARG L CB   1 
ATOM   5467 C CG   . ARG C 3 55  ? 20.651  9.106  11.234  1.00 30.28 ? 55  ARG L CG   1 
ATOM   5468 C CD   . ARG C 3 55  ? 21.047  8.871  12.675  1.00 28.61 ? 55  ARG L CD   1 
ATOM   5469 N NE   . ARG C 3 55  ? 22.321  8.185  12.729  1.00 34.80 ? 55  ARG L NE   1 
ATOM   5470 C CZ   . ARG C 3 55  ? 22.459  6.884  12.534  1.00 40.64 ? 55  ARG L CZ   1 
ATOM   5471 N NH1  . ARG C 3 55  ? 21.419  6.113  12.285  1.00 40.33 ? 55  ARG L NH1  1 
ATOM   5472 N NH2  . ARG C 3 55  ? 23.670  6.346  12.565  1.00 43.47 ? 55  ARG L NH2  1 
ATOM   5473 H H    . ARG C 3 55  ? 22.201  9.081  8.297   1.00 25.11 ? 55  ARG L H    1 
ATOM   5474 H HA   . ARG C 3 55  ? 20.243  10.637 9.219   1.00 24.69 ? 55  ARG L HA   1 
ATOM   5475 H HB2  . ARG C 3 55  ? 22.465  9.418  10.388  1.00 29.77 ? 55  ARG L HB2  1 
ATOM   5476 H HB3  . ARG C 3 55  ? 21.889  10.705 11.121  1.00 29.77 ? 55  ARG L HB3  1 
ATOM   5477 H HG2  . ARG C 3 55  ? 19.790  9.553  11.220  1.00 36.39 ? 55  ARG L HG2  1 
ATOM   5478 H HG3  . ARG C 3 55  ? 20.587  8.248  10.788  1.00 36.39 ? 55  ARG L HG3  1 
ATOM   5479 H HD2  . ARG C 3 55  ? 21.131  9.721  13.134  1.00 34.39 ? 55  ARG L HD2  1 
ATOM   5480 H HD3  . ARG C 3 55  ? 20.378  8.322  13.113  1.00 34.39 ? 55  ARG L HD3  1 
ATOM   5481 H HE   . ARG C 3 55  ? 23.025  8.648  12.898  1.00 41.83 ? 55  ARG L HE   1 
ATOM   5482 H HH11 . ARG C 3 55  ? 20.630  6.454  12.246  1.00 48.45 ? 55  ARG L HH11 1 
ATOM   5483 H HH12 . ARG C 3 55  ? 21.529  5.269  12.160  1.00 48.45 ? 55  ARG L HH12 1 
ATOM   5484 H HH21 . ARG C 3 55  ? 24.357  6.842  12.710  1.00 52.22 ? 55  ARG L HH21 1 
ATOM   5485 H HH22 . ARG C 3 55  ? 23.769  5.501  12.439  1.00 52.22 ? 55  ARG L HH22 1 
ATOM   5486 N N    . ALA C 3 56  ? 21.085  12.938 9.222   1.00 20.09 ? 56  ALA L N    1 
ATOM   5487 C CA   . ALA C 3 56  ? 21.612  14.290 9.123   1.00 19.91 ? 56  ALA L CA   1 
ATOM   5488 C C    . ALA C 3 56  ? 22.449  14.639 10.354  1.00 22.06 ? 56  ALA L C    1 
ATOM   5489 O O    . ALA C 3 56  ? 22.490  13.915 11.343  1.00 21.02 ? 56  ALA L O    1 
ATOM   5490 C CB   . ALA C 3 56  ? 20.497  15.311 8.965   1.00 24.04 ? 56  ALA L CB   1 
ATOM   5491 H H    . ALA C 3 56  ? 20.263  12.896 9.471   1.00 24.16 ? 56  ALA L H    1 
ATOM   5492 H HA   . ALA C 3 56  ? 22.176  14.331 8.335   1.00 23.95 ? 56  ALA L HA   1 
ATOM   5493 H HB1  . ALA C 3 56  ? 20.875  16.203 9.020   1.00 28.91 ? 56  ALA L HB1  1 
ATOM   5494 H HB2  . ALA C 3 56  ? 20.072  15.184 8.102   1.00 28.91 ? 56  ALA L HB2  1 
ATOM   5495 H HB3  . ALA C 3 56  ? 19.848  15.183 9.674   1.00 28.91 ? 56  ALA L HB3  1 
ATOM   5496 N N    . THR C 3 57  ? 23.133  15.776 10.285  1.00 27.60 ? 57  THR L N    1 
ATOM   5497 C CA   . THR C 3 57  ? 24.104  16.114 11.323  1.00 29.63 ? 57  THR L CA   1 
ATOM   5498 C C    . THR C 3 57  ? 23.465  16.241 12.697  1.00 27.61 ? 57  THR L C    1 
ATOM   5499 O O    . THR C 3 57  ? 22.431  16.897 12.856  1.00 28.25 ? 57  THR L O    1 
ATOM   5500 C CB   . THR C 3 57  ? 24.809  17.419 10.962  1.00 37.98 ? 57  THR L CB   1 
ATOM   5501 O OG1  . THR C 3 57  ? 25.062  17.421 9.552   1.00 35.22 ? 57  THR L OG1  1 
ATOM   5502 C CG2  . THR C 3 57  ? 26.106  17.541 11.734  1.00 35.16 ? 57  THR L CG2  1 
ATOM   5503 H H    . THR C 3 57  ? 23.056  16.360 9.659   1.00 33.18 ? 57  THR L H    1 
ATOM   5504 H HA   . THR C 3 57  ? 24.753  15.394 11.372  1.00 35.62 ? 57  THR L HA   1 
ATOM   5505 H HB   . THR C 3 57  ? 24.260  18.185 11.192  1.00 45.64 ? 57  THR L HB   1 
ATOM   5506 H HG1  . THR C 3 57  ? 25.545  18.077 9.347   1.00 42.32 ? 57  THR L HG1  1 
ATOM   5507 H HG21 . THR C 3 57  ? 26.556  18.367 11.498  1.00 42.25 ? 57  THR L HG21 1 
ATOM   5508 H HG22 . THR C 3 57  ? 25.927  17.541 12.687  1.00 42.25 ? 57  THR L HG22 1 
ATOM   5509 H HG23 . THR C 3 57  ? 26.689  16.794 11.524  1.00 42.25 ? 57  THR L HG23 1 
ATOM   5510 N N    . GLY C 3 58  ? 24.087  15.596 13.695  1.00 28.08 ? 58  GLY L N    1 
ATOM   5511 C CA   . GLY C 3 58  ? 23.632  15.774 15.059  1.00 24.20 ? 58  GLY L CA   1 
ATOM   5512 C C    . GLY C 3 58  ? 22.368  15.025 15.391  1.00 27.76 ? 58  GLY L C    1 
ATOM   5513 O O    . GLY C 3 58  ? 21.800  15.220 16.472  1.00 29.36 ? 58  GLY L O    1 
ATOM   5514 H H    . GLY C 3 58  ? 24.757  15.066 13.599  1.00 33.75 ? 58  GLY L H    1 
ATOM   5515 H HA2  . GLY C 3 58  ? 24.327  15.469 15.663  1.00 29.11 ? 58  GLY L HA2  1 
ATOM   5516 H HA3  . GLY C 3 58  ? 23.470  16.718 15.215  1.00 29.11 ? 58  GLY L HA3  1 
ATOM   5517 N N    . ILE C 3 59  ? 21.879  14.218 14.471  1.00 21.09 ? 59  ILE L N    1 
ATOM   5518 C CA   . ILE C 3 59  ? 20.693  13.413 14.743  1.00 18.79 ? 59  ILE L CA   1 
ATOM   5519 C C    . ILE C 3 59  ? 21.112  12.159 15.507  1.00 20.00 ? 59  ILE L C    1 
ATOM   5520 O O    . ILE C 3 59  ? 22.040  11.450 15.062  1.00 19.17 ? 59  ILE L O    1 
ATOM   5521 C CB   . ILE C 3 59  ? 19.989  13.058 13.431  1.00 18.98 ? 59  ILE L CB   1 
ATOM   5522 C CG1  . ILE C 3 59  ? 19.500  14.361 12.759  1.00 19.48 ? 59  ILE L CG1  1 
ATOM   5523 C CG2  . ILE C 3 59  ? 18.797  12.149 13.719  1.00 21.27 ? 59  ILE L CG2  1 
ATOM   5524 C CD1  . ILE C 3 59  ? 18.606  15.235 13.632  1.00 23.71 ? 59  ILE L CD1  1 
ATOM   5525 H H    . ILE C 3 59  ? 22.210  14.114 13.684  1.00 25.37 ? 59  ILE L H    1 
ATOM   5526 H HA   . ILE C 3 59  ? 20.077  13.914 15.300  1.00 22.61 ? 59  ILE L HA   1 
ATOM   5527 H HB   . ILE C 3 59  ? 20.606  12.597 12.843  1.00 22.83 ? 59  ILE L HB   1 
ATOM   5528 H HG12 . ILE C 3 59  ? 20.275  14.890 12.513  1.00 23.44 ? 59  ILE L HG12 1 
ATOM   5529 H HG13 . ILE C 3 59  ? 18.993  14.126 11.966  1.00 23.44 ? 59  ILE L HG13 1 
ATOM   5530 H HG21 . ILE C 3 59  ? 18.185  12.183 12.968  1.00 25.59 ? 59  ILE L HG21 1 
ATOM   5531 H HG22 . ILE C 3 59  ? 19.116  11.242 13.846  1.00 25.59 ? 59  ILE L HG22 1 
ATOM   5532 H HG23 . ILE C 3 59  ? 18.351  12.458 14.523  1.00 25.59 ? 59  ILE L HG23 1 
ATOM   5533 H HD11 . ILE C 3 59  ? 18.014  15.750 13.061  1.00 28.51 ? 59  ILE L HD11 1 
ATOM   5534 H HD12 . ILE C 3 59  ? 18.086  14.667 14.221  1.00 28.51 ? 59  ILE L HD12 1 
ATOM   5535 H HD13 . ILE C 3 59  ? 19.163  15.833 14.155  1.00 28.51 ? 59  ILE L HD13 1 
ATOM   5536 N N    . PRO C 3 60  ? 20.406  11.817 16.591  1.00 20.12 ? 60  PRO L N    1 
ATOM   5537 C CA   . PRO C 3 60  ? 20.756  10.624 17.368  1.00 23.99 ? 60  PRO L CA   1 
ATOM   5538 C C    . PRO C 3 60  ? 20.666  9.342  16.545  1.00 22.24 ? 60  PRO L C    1 
ATOM   5539 O O    . PRO C 3 60  ? 19.874  9.200  15.601  1.00 18.82 ? 60  PRO L O    1 
ATOM   5540 C CB   . PRO C 3 60  ? 19.720  10.638 18.512  1.00 21.49 ? 60  PRO L CB   1 
ATOM   5541 C CG   . PRO C 3 60  ? 19.189  12.009 18.571  1.00 27.37 ? 60  PRO L CG   1 
ATOM   5542 C CD   . PRO C 3 60  ? 19.250  12.522 17.175  1.00 20.26 ? 60  PRO L CD   1 
ATOM   5543 H HA   . PRO C 3 60  ? 21.654  10.705 17.725  1.00 28.85 ? 60  PRO L HA   1 
ATOM   5544 H HB2  . PRO C 3 60  ? 19.012  10.004 18.317  1.00 25.85 ? 60  PRO L HB2  1 
ATOM   5545 H HB3  . PRO C 3 60  ? 20.155  10.402 19.347  1.00 25.85 ? 60  PRO L HB3  1 
ATOM   5546 H HG2  . PRO C 3 60  ? 18.274  11.993 18.893  1.00 32.90 ? 60  PRO L HG2  1 
ATOM   5547 H HG3  . PRO C 3 60  ? 19.738  12.549 19.161  1.00 32.90 ? 60  PRO L HG3  1 
ATOM   5548 H HD2  . PRO C 3 60  ? 18.437  12.304 16.694  1.00 24.37 ? 60  PRO L HD2  1 
ATOM   5549 H HD3  . PRO C 3 60  ? 19.394  13.481 17.167  1.00 24.37 ? 60  PRO L HD3  1 
ATOM   5550 N N    . ASP C 3 61  ? 21.457  8.362  16.973  1.00 21.38 ? 61  ASP L N    1 
ATOM   5551 C CA   . ASP C 3 61  ? 21.538  7.084  16.284  1.00 23.21 ? 61  ASP L CA   1 
ATOM   5552 C C    . ASP C 3 61  ? 20.247  6.273  16.344  1.00 18.62 ? 61  ASP L C    1 
ATOM   5553 O O    . ASP C 3 61  ? 20.096  5.323  15.579  1.00 23.82 ? 61  ASP L O    1 
ATOM   5554 C CB   . ASP C 3 61  ? 22.680  6.256  16.882  1.00 34.77 ? 61  ASP L CB   1 
ATOM   5555 C CG   . ASP C 3 61  ? 23.910  7.103  17.153  1.00 48.81 ? 61  ASP L CG   1 
ATOM   5556 O OD1  . ASP C 3 61  ? 24.725  7.256  16.224  1.00 58.73 ? 61  ASP L OD1  1 
ATOM   5557 O OD2  . ASP C 3 61  ? 24.035  7.650  18.267  1.00 46.04 ? 61  ASP L OD2  1 
ATOM   5558 H H    . ASP C 3 61  ? 21.960  8.414  17.669  1.00 25.71 ? 61  ASP L H    1 
ATOM   5559 H HA   . ASP C 3 61  ? 21.727  7.255  15.348  1.00 27.91 ? 61  ASP L HA   1 
ATOM   5560 H HB2  . ASP C 3 61  ? 22.388  5.868  17.722  1.00 41.79 ? 61  ASP L HB2  1 
ATOM   5561 H HB3  . ASP C 3 61  ? 22.926  5.554  16.260  1.00 41.79 ? 61  ASP L HB3  1 
ATOM   5562 N N    . ARG C 3 62  ? 19.324  6.594  17.249  1.00 19.85 ? 62  ARG L N    1 
ATOM   5563 C CA   . ARG C 3 62  ? 18.110  5.811  17.312  1.00 17.97 ? 62  ARG L CA   1 
ATOM   5564 C C    . ARG C 3 62  ? 17.224  6.056  16.109  1.00 13.15 ? 62  ARG L C    1 
ATOM   5565 O O    . ARG C 3 62  ? 16.281  5.301  15.898  1.00 14.48 ? 62  ARG L O    1 
ATOM   5566 C CB   . ARG C 3 62  ? 17.310  6.100  18.585  1.00 15.62 ? 62  ARG L CB   1 
ATOM   5567 C CG   . ARG C 3 62  ? 16.824  7.541  18.744  1.00 15.51 ? 62  ARG L CG   1 
ATOM   5568 C CD   . ARG C 3 62  ? 16.190  7.707  20.104  1.00 16.87 ? 62  ARG L CD   1 
ATOM   5569 N NE   . ARG C 3 62  ? 15.776  9.082  20.296  1.00 14.93 ? 62  ARG L NE   1 
ATOM   5570 C CZ   . ARG C 3 62  ? 16.513  10.022 20.862  1.00 18.63 ? 62  ARG L CZ   1 
ATOM   5571 N NH1  . ARG C 3 62  ? 17.786  9.798  21.213  1.00 16.73 ? 62  ARG L NH1  1 
ATOM   5572 N NH2  . ARG C 3 62  ? 15.975  11.228 21.042  1.00 17.21 ? 62  ARG L NH2  1 
ATOM   5573 H H    . ARG C 3 62  ? 19.381  7.238  17.815  1.00 23.89 ? 62  ARG L H    1 
ATOM   5574 H HA   . ARG C 3 62  ? 18.367  4.876  17.343  1.00 21.62 ? 62  ARG L HA   1 
ATOM   5575 H HB2  . ARG C 3 62  ? 16.526  5.529  18.589  1.00 18.81 ? 62  ARG L HB2  1 
ATOM   5576 H HB3  . ARG C 3 62  ? 17.871  5.899  19.350  1.00 18.81 ? 62  ARG L HB3  1 
ATOM   5577 H HG2  . ARG C 3 62  ? 17.574  8.152  18.670  1.00 18.67 ? 62  ARG L HG2  1 
ATOM   5578 H HG3  . ARG C 3 62  ? 16.163  7.743  18.062  1.00 18.67 ? 62  ARG L HG3  1 
ATOM   5579 H HD2  . ARG C 3 62  ? 15.409  7.135  20.172  1.00 20.30 ? 62  ARG L HD2  1 
ATOM   5580 H HD3  . ARG C 3 62  ? 16.832  7.476  20.793  1.00 20.30 ? 62  ARG L HD3  1 
ATOM   5581 H HE   . ARG C 3 62  ? 14.991  9.303  20.022  1.00 17.98 ? 62  ARG L HE   1 
ATOM   5582 H HH11 . ARG C 3 62  ? 18.142  9.028  21.072  1.00 20.13 ? 62  ARG L HH11 1 
ATOM   5583 H HH12 . ARG C 3 62  ? 18.248  10.424 21.580  1.00 20.13 ? 62  ARG L HH12 1 
ATOM   5584 H HH21 . ARG C 3 62  ? 15.166  11.379 20.793  1.00 20.71 ? 62  ARG L HH21 1 
ATOM   5585 H HH22 . ARG C 3 62  ? 16.436  11.854 21.408  1.00 20.71 ? 62  ARG L HH22 1 
ATOM   5586 N N    . PHE C 3 63  ? 17.491  7.102  15.327  1.00 16.52 ? 63  PHE L N    1 
ATOM   5587 C CA   . PHE C 3 63  ? 16.744  7.369  14.107  1.00 15.12 ? 63  PHE L CA   1 
ATOM   5588 C C    . PHE C 3 63  ? 17.387  6.661  12.937  1.00 16.75 ? 63  PHE L C    1 
ATOM   5589 O O    . PHE C 3 63  ? 18.565  6.863  12.664  1.00 18.55 ? 63  PHE L O    1 
ATOM   5590 C CB   . PHE C 3 63  ? 16.656  8.878  13.812  1.00 14.86 ? 63  PHE L CB   1 
ATOM   5591 C CG   . PHE C 3 63  ? 15.860  9.641  14.820  1.00 12.09 ? 63  PHE L CG   1 
ATOM   5592 C CD1  . PHE C 3 63  ? 14.483  9.738  14.660  1.00 13.32 ? 63  PHE L CD1  1 
ATOM   5593 C CD2  . PHE C 3 63  ? 16.450  10.273 15.900  1.00 15.68 ? 63  PHE L CD2  1 
ATOM   5594 C CE1  . PHE C 3 63  ? 13.728  10.433 15.581  1.00 13.84 ? 63  PHE L CE1  1 
ATOM   5595 C CE2  . PHE C 3 63  ? 15.681  10.921 16.839  1.00 15.39 ? 63  PHE L CE2  1 
ATOM   5596 C CZ   . PHE C 3 63  ? 14.322  11.027 16.648  1.00 14.97 ? 63  PHE L CZ   1 
ATOM   5597 H H    . PHE C 3 63  ? 18.110  7.677  15.487  1.00 19.88 ? 63  PHE L H    1 
ATOM   5598 H HA   . PHE C 3 63  ? 15.843  7.031  14.223  1.00 18.21 ? 63  PHE L HA   1 
ATOM   5599 H HB2  . PHE C 3 63  ? 17.554  9.247  13.803  1.00 17.89 ? 63  PHE L HB2  1 
ATOM   5600 H HB3  . PHE C 3 63  ? 16.237  9.003  12.947  1.00 17.89 ? 63  PHE L HB3  1 
ATOM   5601 H HD1  . PHE C 3 63  ? 14.070  9.333  13.931  1.00 16.05 ? 63  PHE L HD1  1 
ATOM   5602 H HD2  . PHE C 3 63  ? 17.375  10.259 15.991  1.00 18.88 ? 63  PHE L HD2  1 
ATOM   5603 H HE1  . PHE C 3 63  ? 12.807  10.496 15.470  1.00 16.67 ? 63  PHE L HE1  1 
ATOM   5604 H HE2  . PHE C 3 63  ? 16.078  11.284 17.598  1.00 18.53 ? 63  PHE L HE2  1 
ATOM   5605 H HZ   . PHE C 3 63  ? 13.807  11.508 17.255  1.00 18.02 ? 63  PHE L HZ   1 
ATOM   5606 N N    . SER C 3 64  ? 16.605  5.868  12.230  1.00 15.71 ? 64  SER L N    1 
ATOM   5607 C CA   . SER C 3 64  ? 17.110  5.225  11.032  1.00 19.80 ? 64  SER L CA   1 
ATOM   5608 C C    . SER C 3 64  ? 16.031  5.213  9.974   1.00 16.65 ? 64  SER L C    1 
ATOM   5609 O O    . SER C 3 64  ? 14.849  5.427  10.253  1.00 16.70 ? 64  SER L O    1 
ATOM   5610 C CB   . SER C 3 64  ? 17.635  3.822  11.350  1.00 19.86 ? 64  SER L CB   1 
ATOM   5611 O OG   . SER C 3 64  ? 16.580  2.938  11.594  1.00 20.55 ? 64  SER L OG   1 
ATOM   5612 H H    . SER C 3 64  ? 15.786  5.689  12.421  1.00 18.91 ? 64  SER L H    1 
ATOM   5613 H HA   . SER C 3 64  ? 17.847  5.732  10.658  1.00 23.82 ? 64  SER L HA   1 
ATOM   5614 H HB2  . SER C 3 64  ? 18.150  3.499  10.594  1.00 23.89 ? 64  SER L HB2  1 
ATOM   5615 H HB3  . SER C 3 64  ? 18.198  3.867  12.139  1.00 23.89 ? 64  SER L HB3  1 
ATOM   5616 H HG   . SER C 3 64  ? 16.879  2.206  11.878  1.00 24.72 ? 64  SER L HG   1 
ATOM   5617 N N    . GLY C 3 65  ? 16.457  5.023  8.734   1.00 17.84 ? 65  GLY L N    1 
ATOM   5618 C CA   . GLY C 3 65  ? 15.527  4.953  7.626   1.00 16.48 ? 65  GLY L CA   1 
ATOM   5619 C C    . GLY C 3 65  ? 15.863  3.788  6.722   1.00 17.50 ? 65  GLY L C    1 
ATOM   5620 O O    . GLY C 3 65  ? 17.017  3.363  6.621   1.00 19.64 ? 65  GLY L O    1 
ATOM   5621 H H    . GLY C 3 65  ? 17.282  4.933  8.510   1.00 21.47 ? 65  GLY L H    1 
ATOM   5622 H HA2  . GLY C 3 65  ? 14.624  4.839  7.962   1.00 19.84 ? 65  GLY L HA2  1 
ATOM   5623 H HA3  . GLY C 3 65  ? 15.570  5.773  7.109   1.00 19.84 ? 65  GLY L HA3  1 
ATOM   5624 N N    . SER C 3 66  ? 14.837  3.288  6.040   1.00 15.06 ? 66  SER L N    1 
ATOM   5625 C CA   . SER C 3 66  ? 15.028  2.212  5.090   1.00 19.78 ? 66  SER L CA   1 
ATOM   5626 C C    . SER C 3 66  ? 13.985  2.339  3.992   1.00 19.70 ? 66  SER L C    1 
ATOM   5627 O O    . SER C 3 66  ? 13.053  3.155  4.067   1.00 19.26 ? 66  SER L O    1 
ATOM   5628 C CB   . SER C 3 66  ? 14.899  0.853  5.771   1.00 23.10 ? 66  SER L CB   1 
ATOM   5629 O OG   . SER C 3 66  ? 13.646  0.744  6.463   1.00 28.39 ? 66  SER L OG   1 
ATOM   5630 H H    . SER C 3 66  ? 14.024  3.558  6.114   1.00 18.13 ? 66  SER L H    1 
ATOM   5631 H HA   . SER C 3 66  ? 15.911  2.288  4.696   1.00 23.80 ? 66  SER L HA   1 
ATOM   5632 H HB2  . SER C 3 66  ? 14.949  0.156  5.097   1.00 27.78 ? 66  SER L HB2  1 
ATOM   5633 H HB3  . SER C 3 66  ? 15.622  0.749  6.409   1.00 27.78 ? 66  SER L HB3  1 
ATOM   5634 H HG   . SER C 3 66  ? 13.012  0.750  5.912   1.00 34.13 ? 66  SER L HG   1 
ATOM   5635 N N    . GLY C 3 67  ? 14.170  1.550  2.942   1.00 21.53 ? 67  GLY L N    1 
ATOM   5636 C CA   . GLY C 3 67  ? 13.236  1.515  1.843   1.00 22.20 ? 67  GLY L CA   1 
ATOM   5637 C C    . GLY C 3 67  ? 13.891  1.860  0.522   1.00 19.26 ? 67  GLY L C    1 
ATOM   5638 O O    . GLY C 3 67  ? 15.067  2.222  0.445   1.00 24.90 ? 67  GLY L O    1 
ATOM   5639 H H    . GLY C 3 67  ? 14.841  1.021  2.849   1.00 25.89 ? 67  GLY L H    1 
ATOM   5640 H HA2  . GLY C 3 67  ? 12.855  0.625  1.773   1.00 26.71 ? 67  GLY L HA2  1 
ATOM   5641 H HA3  . GLY C 3 67  ? 12.522  2.152  2.006   1.00 26.71 ? 67  GLY L HA3  1 
ATOM   5642 N N    . SER C 3 68  ? 13.082  1.720  -0.531  1.00 25.23 ? 68  SER L N    1 
ATOM   5643 C CA   . SER C 3 68  ? 13.504  1.946  -1.907  1.00 23.73 ? 68  SER L CA   1 
ATOM   5644 C C    . SER C 3 68  ? 12.261  1.937  -2.801  1.00 26.85 ? 68  SER L C    1 
ATOM   5645 O O    . SER C 3 68  ? 11.163  1.537  -2.391  1.00 23.96 ? 68  SER L O    1 
ATOM   5646 C CB   . SER C 3 68  ? 14.474  0.878  -2.398  1.00 24.65 ? 68  SER L CB   1 
ATOM   5647 O OG   . SER C 3 68  ? 13.781  -0.354 -2.461  1.00 25.77 ? 68  SER L OG   1 
ATOM   5648 H H    . SER C 3 68  ? 12.256  1.486  -0.467  1.00 30.34 ? 68  SER L H    1 
ATOM   5649 H HA   . SER C 3 68  ? 13.934  2.814  -1.949  1.00 28.54 ? 68  SER L HA   1 
ATOM   5650 H HB2  . SER C 3 68  ? 14.800  1.114  -3.281  1.00 29.64 ? 68  SER L HB2  1 
ATOM   5651 H HB3  . SER C 3 68  ? 15.217  0.803  -1.779  1.00 29.64 ? 68  SER L HB3  1 
ATOM   5652 H HG   . SER C 3 68  ? 14.195  -0.892 -2.957  1.00 30.99 ? 68  SER L HG   1 
ATOM   5653 N N    . GLY C 3 69  ? 12.455  2.359  -4.046  1.00 21.56 ? 69  GLY L N    1 
ATOM   5654 C CA   . GLY C 3 69  ? 11.358  2.408  -4.992  1.00 25.38 ? 69  GLY L CA   1 
ATOM   5655 C C    . GLY C 3 69  ? 10.291  3.367  -4.511  1.00 24.72 ? 69  GLY L C    1 
ATOM   5656 O O    . GLY C 3 69  ? 10.516  4.592  -4.530  1.00 24.99 ? 69  GLY L O    1 
ATOM   5657 H H    . GLY C 3 69  ? 13.211  2.620  -4.363  1.00 25.94 ? 69  GLY L H    1 
ATOM   5658 H HA2  . GLY C 3 69  ? 11.682  2.706  -5.857  1.00 30.52 ? 69  GLY L HA2  1 
ATOM   5659 H HA3  . GLY C 3 69  ? 10.967  1.525  -5.089  1.00 30.52 ? 69  GLY L HA3  1 
ATOM   5660 N N    . THR C 3 70  ? 9.144   2.832  -4.038  1.00 22.82 ? 70  THR L N    1 
ATOM   5661 C CA   . THR C 3 70  ? 8.023   3.666  -3.622  1.00 21.36 ? 70  THR L CA   1 
ATOM   5662 C C    . THR C 3 70  ? 7.733   3.599  -2.126  1.00 23.83 ? 70  THR L C    1 
ATOM   5663 O O    . THR C 3 70  ? 6.882   4.360  -1.657  1.00 25.20 ? 70  THR L O    1 
ATOM   5664 C CB   . THR C 3 70  ? 6.690   3.276  -4.289  1.00 25.62 ? 70  THR L CB   1 
ATOM   5665 O OG1  . THR C 3 70  ? 6.501   1.874  -4.186  1.00 26.14 ? 70  THR L OG1  1 
ATOM   5666 C CG2  . THR C 3 70  ? 6.697   3.669  -5.785  1.00 28.64 ? 70  THR L CG2  1 
ATOM   5667 H H    . THR C 3 70  ? 9.003   1.988  -3.953  1.00 27.45 ? 70  THR L H    1 
ATOM   5668 H HA   . THR C 3 70  ? 8.265   4.562  -3.902  1.00 25.69 ? 70  THR L HA   1 
ATOM   5669 H HB   . THR C 3 70  ? 5.962   3.741  -3.848  1.00 30.81 ? 70  THR L HB   1 
ATOM   5670 H HG1  . THR C 3 70  ? 5.901   1.625  -4.719  1.00 31.43 ? 70  THR L HG1  1 
ATOM   5671 H HG21 . THR C 3 70  ? 5.875   3.377  -6.209  1.00 34.43 ? 70  THR L HG21 1 
ATOM   5672 H HG22 . THR C 3 70  ? 6.772   4.632  -5.874  1.00 34.43 ? 70  THR L HG22 1 
ATOM   5673 H HG23 . THR C 3 70  ? 7.448   3.252  -6.234  1.00 34.43 ? 70  THR L HG23 1 
ATOM   5674 N N    . ASP C 3 71  ? 8.350   2.682  -1.369  1.00 24.05 ? 71  ASP L N    1 
ATOM   5675 C CA   . ASP C 3 71  ? 7.937   2.413  0.009   1.00 25.34 ? 71  ASP L CA   1 
ATOM   5676 C C    . ASP C 3 71  ? 9.111   2.656  0.941   1.00 24.16 ? 71  ASP L C    1 
ATOM   5677 O O    . ASP C 3 71  ? 10.141  1.981  0.838   1.00 20.75 ? 71  ASP L O    1 
ATOM   5678 C CB   . ASP C 3 71  ? 7.455   0.973  0.215   1.00 26.71 ? 71  ASP L CB   1 
ATOM   5679 C CG   . ASP C 3 71  ? 6.270   0.611  -0.643  1.00 39.78 ? 71  ASP L CG   1 
ATOM   5680 O OD1  . ASP C 3 71  ? 5.595   1.510  -1.196  1.00 38.82 ? 71  ASP L OD1  1 
ATOM   5681 O OD2  . ASP C 3 71  ? 6.009   -0.601 -0.764  1.00 48.78 ? 71  ASP L OD2  1 
ATOM   5682 H H    . ASP C 3 71  ? 9.012   2.203  -1.636  1.00 28.92 ? 71  ASP L H    1 
ATOM   5683 H HA   . ASP C 3 71  ? 7.211   3.022  0.213   1.00 30.47 ? 71  ASP L HA   1 
ATOM   5684 H HB2  . ASP C 3 71  ? 8.178   0.366  -0.005  1.00 32.11 ? 71  ASP L HB2  1 
ATOM   5685 H HB3  . ASP C 3 71  ? 7.195   0.859  1.143   1.00 32.11 ? 71  ASP L HB3  1 
ATOM   5686 N N    . PHE C 3 72  ? 8.925   3.570  1.896   1.00 17.71 ? 72  PHE L N    1 
ATOM   5687 C CA   . PHE C 3 72  ? 10.007  4.016  2.766   1.00 18.61 ? 72  PHE L CA   1 
ATOM   5688 C C    . PHE C 3 72  ? 9.520   4.009  4.203   1.00 15.18 ? 72  PHE L C    1 
ATOM   5689 O O    . PHE C 3 72  ? 8.330   4.136  4.460   1.00 16.56 ? 72  PHE L O    1 
ATOM   5690 C CB   . PHE C 3 72  ? 10.498  5.394  2.373   1.00 18.23 ? 72  PHE L CB   1 
ATOM   5691 C CG   . PHE C 3 72  ? 11.032  5.454  0.969   1.00 14.19 ? 72  PHE L CG   1 
ATOM   5692 C CD1  . PHE C 3 72  ? 12.351  5.163  0.710   1.00 18.66 ? 72  PHE L CD1  1 
ATOM   5693 C CD2  . PHE C 3 72  ? 10.186  5.735  -0.092  1.00 18.59 ? 72  PHE L CD2  1 
ATOM   5694 C CE1  . PHE C 3 72  ? 12.854  5.194  -0.570  1.00 21.71 ? 72  PHE L CE1  1 
ATOM   5695 C CE2  . PHE C 3 72  ? 10.692  5.780  -1.392  1.00 23.58 ? 72  PHE L CE2  1 
ATOM   5696 C CZ   . PHE C 3 72  ? 12.035  5.509  -1.617  1.00 21.47 ? 72  PHE L CZ   1 
ATOM   5697 H H    . PHE C 3 72  ? 8.170   3.949  2.059   1.00 21.31 ? 72  PHE L H    1 
ATOM   5698 H HA   . PHE C 3 72  ? 10.761  3.410  2.703   1.00 22.39 ? 72  PHE L HA   1 
ATOM   5699 H HB2  . PHE C 3 72  ? 9.760   6.020  2.438   1.00 21.94 ? 72  PHE L HB2  1 
ATOM   5700 H HB3  . PHE C 3 72  ? 11.211  5.656  2.975   1.00 21.94 ? 72  PHE L HB3  1 
ATOM   5701 H HD1  . PHE C 3 72  ? 12.914  4.940  1.416   1.00 22.45 ? 72  PHE L HD1  1 
ATOM   5702 H HD2  . PHE C 3 72  ? 9.283   5.893  0.062   1.00 22.36 ? 72  PHE L HD2  1 
ATOM   5703 H HE1  . PHE C 3 72  ? 13.751  5.001  -0.722  1.00 26.11 ? 72  PHE L HE1  1 
ATOM   5704 H HE2  . PHE C 3 72  ? 10.132  5.990  -2.104  1.00 28.36 ? 72  PHE L HE2  1 
ATOM   5705 H HZ   . PHE C 3 72  ? 12.377  5.541  -2.481  1.00 25.82 ? 72  PHE L HZ   1 
ATOM   5706 N N    . THR C 3 73  ? 10.459  3.826  5.125   1.00 14.65 ? 73  THR L N    1 
ATOM   5707 C CA   . THR C 3 73  ? 10.143  3.803  6.544   1.00 16.10 ? 73  THR L CA   1 
ATOM   5708 C C    . THR C 3 73  ? 11.178  4.571  7.374   1.00 16.78 ? 73  THR L C    1 
ATOM   5709 O O    . THR C 3 73  ? 12.388  4.600  7.095   1.00 15.31 ? 73  THR L O    1 
ATOM   5710 C CB   . THR C 3 73  ? 10.000  2.364  7.085   1.00 23.96 ? 73  THR L CB   1 
ATOM   5711 O OG1  . THR C 3 73  ? 11.285  1.900  7.466   1.00 35.86 ? 73  THR L OG1  1 
ATOM   5712 C CG2  . THR C 3 73  ? 9.401   1.459  6.079   1.00 16.50 ? 73  THR L CG2  1 
ATOM   5713 H H    . THR C 3 73  ? 11.293  3.711  4.949   1.00 17.64 ? 73  THR L H    1 
ATOM   5714 H HA   . THR C 3 73  ? 9.298   4.266  6.659   1.00 19.38 ? 73  THR L HA   1 
ATOM   5715 H HB   . THR C 3 73  ? 9.405   2.356  7.850   1.00 28.81 ? 73  THR L HB   1 
ATOM   5716 H HG1  . THR C 3 73  ? 11.224  1.135  7.807   1.00 43.09 ? 73  THR L HG1  1 
ATOM   5717 H HG21 . THR C 3 73  ? 9.309   0.567  6.448   1.00 19.86 ? 73  THR L HG21 1 
ATOM   5718 H HG22 . THR C 3 73  ? 8.524   1.784  5.821   1.00 19.86 ? 73  THR L HG22 1 
ATOM   5719 H HG23 . THR C 3 73  ? 9.965   1.418  5.291   1.00 19.86 ? 73  THR L HG23 1 
ATOM   5720 N N    . LEU C 3 74  ? 10.660  5.219  8.394   1.00 13.32 ? 74  LEU L N    1 
ATOM   5721 C CA   . LEU C 3 74  ? 11.470  5.850  9.427   1.00 14.15 ? 74  LEU L CA   1 
ATOM   5722 C C    . LEU C 3 74  ? 11.296  5.014  10.678  1.00 12.19 ? 74  LEU L C    1 
ATOM   5723 O O    . LEU C 3 74  ? 10.155  4.697  11.055  1.00 15.39 ? 74  LEU L O    1 
ATOM   5724 C CB   . LEU C 3 74  ? 11.006  7.275  9.724   1.00 12.68 ? 74  LEU L CB   1 
ATOM   5725 C CG   . LEU C 3 74  ? 11.678  8.007  10.891  1.00 12.41 ? 74  LEU L CG   1 
ATOM   5726 C CD1  . LEU C 3 74  ? 13.116  8.280  10.552  1.00 16.42 ? 74  LEU L CD1  1 
ATOM   5727 C CD2  . LEU C 3 74  ? 10.927  9.278  11.209  1.00 12.38 ? 74  LEU L CD2  1 
ATOM   5728 H H    . LEU C 3 74  ? 9.815   5.313  8.519   1.00 16.04 ? 74  LEU L H    1 
ATOM   5729 H HA   . LEU C 3 74  ? 12.398  5.891  9.148   1.00 17.04 ? 74  LEU L HA   1 
ATOM   5730 H HB2  . LEU C 3 74  ? 11.162  7.810  8.929   1.00 15.28 ? 74  LEU L HB2  1 
ATOM   5731 H HB3  . LEU C 3 74  ? 10.057  7.244  9.921   1.00 15.28 ? 74  LEU L HB3  1 
ATOM   5732 H HG   . LEU C 3 74  ? 11.662  7.457  11.689  1.00 14.95 ? 74  LEU L HG   1 
ATOM   5733 H HD11 . LEU C 3 74  ? 13.529  8.756  11.289  1.00 19.76 ? 74  LEU L HD11 1 
ATOM   5734 H HD12 . LEU C 3 74  ? 13.571  7.437  10.405  1.00 19.76 ? 74  LEU L HD12 1 
ATOM   5735 H HD13 . LEU C 3 74  ? 13.153  8.821  9.747   1.00 19.76 ? 74  LEU L HD13 1 
ATOM   5736 H HD21 . LEU C 3 74  ? 11.341  9.707  11.974  1.00 14.92 ? 74  LEU L HD21 1 
ATOM   5737 H HD22 . LEU C 3 74  ? 10.963  9.867  10.439  1.00 14.92 ? 74  LEU L HD22 1 
ATOM   5738 H HD23 . LEU C 3 74  ? 10.005  9.057  11.412  1.00 14.92 ? 74  LEU L HD23 1 
ATOM   5739 N N    . THR C 3 75  ? 12.400  4.647  11.310  1.00 13.59 ? 75  THR L N    1 
ATOM   5740 C CA   . THR C 3 75  ? 12.354  3.895  12.553  1.00 13.48 ? 75  THR L CA   1 
ATOM   5741 C C    . THR C 3 75  ? 13.021  4.695  13.654  1.00 14.34 ? 75  THR L C    1 
ATOM   5742 O O    . THR C 3 75  ? 14.137  5.223  13.482  1.00 15.89 ? 75  THR L O    1 
ATOM   5743 C CB   . THR C 3 75  ? 13.053  2.546  12.377  1.00 17.98 ? 75  THR L CB   1 
ATOM   5744 O OG1  . THR C 3 75  ? 12.375  1.797  11.356  1.00 20.57 ? 75  THR L OG1  1 
ATOM   5745 C CG2  . THR C 3 75  ? 13.026  1.748  13.688  1.00 20.05 ? 75  THR L CG2  1 
ATOM   5746 H H    . THR C 3 75  ? 13.195  4.824  11.035  1.00 16.37 ? 75  THR L H    1 
ATOM   5747 H HA   . THR C 3 75  ? 11.432  3.742  12.816  1.00 16.24 ? 75  THR L HA   1 
ATOM   5748 H HB   . THR C 3 75  ? 13.979  2.687  12.125  1.00 21.64 ? 75  THR L HB   1 
ATOM   5749 H HG1  . THR C 3 75  ? 12.859  1.160  11.098  1.00 24.75 ? 75  THR L HG1  1 
ATOM   5750 H HG21 . THR C 3 75  ? 13.487  0.903  13.571  1.00 24.12 ? 75  THR L HG21 1 
ATOM   5751 H HG22 . THR C 3 75  ? 13.464  2.251  14.392  1.00 24.12 ? 75  THR L HG22 1 
ATOM   5752 H HG23 . THR C 3 75  ? 12.108  1.572  13.950  1.00 24.12 ? 75  THR L HG23 1 
ATOM   5753 N N    . ILE C 3 76  ? 12.345  4.770  14.786  1.00 13.19 ? 76  ILE L N    1 
ATOM   5754 C CA   . ILE C 3 76  ? 12.916  5.235  16.033  1.00 13.60 ? 76  ILE L CA   1 
ATOM   5755 C C    . ILE C 3 76  ? 13.025  3.979  16.867  1.00 13.83 ? 76  ILE L C    1 
ATOM   5756 O O    . ILE C 3 76  ? 12.001  3.438  17.289  1.00 13.32 ? 76  ILE L O    1 
ATOM   5757 C CB   . ILE C 3 76  ? 12.039  6.277  16.714  1.00 13.00 ? 76  ILE L CB   1 
ATOM   5758 C CG1  . ILE C 3 76  ? 11.727  7.393  15.714  1.00 15.94 ? 76  ILE L CG1  1 
ATOM   5759 C CG2  . ILE C 3 76  ? 12.794  6.899  17.897  1.00 15.57 ? 76  ILE L CG2  1 
ATOM   5760 C CD1  . ILE C 3 76  ? 10.899  8.578  16.305  1.00 17.94 ? 76  ILE L CD1  1 
ATOM   5761 H H    . ILE C 3 76  ? 11.518  4.547  14.858  1.00 15.89 ? 76  ILE L H    1 
ATOM   5762 H HA   . ILE C 3 76  ? 13.787  5.641  15.899  1.00 16.38 ? 76  ILE L HA   1 
ATOM   5763 H HB   . ILE C 3 76  ? 11.224  5.852  17.023  1.00 15.66 ? 76  ILE L HB   1 
ATOM   5764 H HG12 . ILE C 3 76  ? 12.564  7.756  15.385  1.00 19.19 ? 76  ILE L HG12 1 
ATOM   5765 H HG13 . ILE C 3 76  ? 11.217  7.016  14.979  1.00 19.19 ? 76  ILE L HG13 1 
ATOM   5766 H HG21 . ILE C 3 76  ? 12.284  7.650  18.238  1.00 18.75 ? 76  ILE L HG21 1 
ATOM   5767 H HG22 . ILE C 3 76  ? 12.900  6.229  18.591  1.00 18.75 ? 76  ILE L HG22 1 
ATOM   5768 H HG23 . ILE C 3 76  ? 13.664  7.200  17.593  1.00 18.75 ? 76  ILE L HG23 1 
ATOM   5769 H HD11 . ILE C 3 76  ? 10.547  9.113  15.576  1.00 21.58 ? 76  ILE L HD11 1 
ATOM   5770 H HD12 . ILE C 3 76  ? 10.169  8.220  16.834  1.00 21.58 ? 76  ILE L HD12 1 
ATOM   5771 H HD13 . ILE C 3 76  ? 11.477  9.120  16.864  1.00 21.58 ? 76  ILE L HD13 1 
ATOM   5772 N N    . SER C 3 77  ? 14.244  3.494  17.043  1.00 13.13 ? 77  SER L N    1 
ATOM   5773 C CA   . SER C 3 77  ? 14.474  2.173  17.616  1.00 13.04 ? 77  SER L CA   1 
ATOM   5774 C C    . SER C 3 77  ? 13.894  2.042  19.025  1.00 16.72 ? 77  SER L C    1 
ATOM   5775 O O    . SER C 3 77  ? 13.108  1.125  19.278  1.00 17.26 ? 77  SER L O    1 
ATOM   5776 C CB   . SER C 3 77  ? 15.973  1.910  17.552  1.00 16.73 ? 77  SER L CB   1 
ATOM   5777 O OG   . SER C 3 77  ? 16.638  2.763  18.474  1.00 20.05 ? 77  SER L OG   1 
ATOM   5778 H H    . SER C 3 77  ? 14.966  3.913  16.838  1.00 15.82 ? 77  SER L H    1 
ATOM   5779 H HA   . SER C 3 77  ? 14.017  1.488  17.103  1.00 15.71 ? 77  SER L HA   1 
ATOM   5780 H HB2  . SER C 3 77  ? 16.148  0.985  17.784  1.00 20.14 ? 77  SER L HB2  1 
ATOM   5781 H HB3  . SER C 3 77  ? 16.294  2.093  16.655  1.00 20.14 ? 77  SER L HB3  1 
ATOM   5782 H HG   . SER C 3 77  ? 17.439  2.525  18.559  1.00 24.12 ? 77  SER L HG   1 
ATOM   5783 N N    . ARG C 3 78  ? 14.231  2.974  19.919  1.00 14.62 ? 78  ARG L N    1 
ATOM   5784 C CA   . ARG C 3 78  ? 13.742  3.021  21.305  1.00 14.85 ? 78  ARG L CA   1 
ATOM   5785 C C    . ARG C 3 78  ? 13.342  4.470  21.572  1.00 13.87 ? 78  ARG L C    1 
ATOM   5786 O O    . ARG C 3 78  ? 14.211  5.346  21.644  1.00 16.12 ? 78  ARG L O    1 
ATOM   5787 C CB   . ARG C 3 78  ? 14.791  2.550  22.322  1.00 16.67 ? 78  ARG L CB   1 
ATOM   5788 C CG   . ARG C 3 78  ? 15.077  1.047  22.202  1.00 26.39 ? 78  ARG L CG   1 
ATOM   5789 C CD   . ARG C 3 78  ? 16.267  0.650  23.077  1.00 29.95 ? 78  ARG L CD   1 
ATOM   5790 N NE   . ARG C 3 78  ? 17.483  1.368  22.714  1.00 40.17 ? 78  ARG L NE   1 
ATOM   5791 C CZ   . ARG C 3 78  ? 18.267  1.069  21.682  1.00 44.21 ? 78  ARG L CZ   1 
ATOM   5792 N NH1  . ARG C 3 78  ? 17.996  0.047  20.873  1.00 35.73 ? 78  ARG L NH1  1 
ATOM   5793 N NH2  . ARG C 3 78  ? 19.347  1.819  21.447  1.00 45.39 ? 78  ARG L NH2  1 
ATOM   5794 H H    . ARG C 3 78  ? 14.768  3.622  19.741  1.00 17.61 ? 78  ARG L H    1 
ATOM   5795 H HA   . ARG C 3 78  ? 12.973  2.437  21.397  1.00 17.88 ? 78  ARG L HA   1 
ATOM   5796 H HB2  . ARG C 3 78  ? 15.620  3.029  22.169  1.00 20.06 ? 78  ARG L HB2  1 
ATOM   5797 H HB3  . ARG C 3 78  ? 14.466  2.726  23.219  1.00 20.06 ? 78  ARG L HB3  1 
ATOM   5798 H HG2  . ARG C 3 78  ? 14.300  0.545  22.493  1.00 31.73 ? 78  ARG L HG2  1 
ATOM   5799 H HG3  . ARG C 3 78  ? 15.287  0.830  21.280  1.00 31.73 ? 78  ARG L HG3  1 
ATOM   5800 H HD2  . ARG C 3 78  ? 16.063  0.852  24.004  1.00 36.00 ? 78  ARG L HD2  1 
ATOM   5801 H HD3  . ARG C 3 78  ? 16.436  -0.300 22.974  1.00 36.00 ? 78  ARG L HD3  1 
ATOM   5802 H HE   . ARG C 3 78  ? 17.711  2.037  23.205  1.00 48.27 ? 78  ARG L HE   1 
ATOM   5803 H HH11 . ARG C 3 78  ? 17.300  -0.438 21.012  1.00 42.94 ? 78  ARG L HH11 1 
ATOM   5804 H HH12 . ARG C 3 78  ? 18.518  -0.127 20.212  1.00 42.94 ? 78  ARG L HH12 1 
ATOM   5805 H HH21 . ARG C 3 78  ? 19.528  2.485  21.960  1.00 54.53 ? 78  ARG L HH21 1 
ATOM   5806 H HH22 . ARG C 3 78  ? 19.862  1.636  20.783  1.00 54.53 ? 78  ARG L HH22 1 
ATOM   5807 N N    . LEU C 3 79  ? 12.037  4.729  21.589  1.00 11.89 ? 79  LEU L N    1 
ATOM   5808 C CA   . LEU C 3 79  ? 11.541  6.097  21.657  1.00 12.02 ? 79  LEU L CA   1 
ATOM   5809 C C    . LEU C 3 79  ? 11.984  6.786  22.940  1.00 12.26 ? 79  LEU L C    1 
ATOM   5810 O O    . LEU C 3 79  ? 11.863  6.233  24.039  1.00 14.27 ? 79  LEU L O    1 
ATOM   5811 C CB   . LEU C 3 79  ? 10.017  6.095  21.632  1.00 14.23 ? 79  LEU L CB   1 
ATOM   5812 C CG   . LEU C 3 79  ? 9.275   7.320  21.111  1.00 17.78 ? 79  LEU L CG   1 
ATOM   5813 C CD1  . LEU C 3 79  ? 9.457   7.601  19.642  1.00 16.84 ? 79  LEU L CD1  1 
ATOM   5814 C CD2  . LEU C 3 79  ? 7.803   7.163  21.483  1.00 28.48 ? 79  LEU L CD2  1 
ATOM   5815 H H    . LEU C 3 79  ? 11.420  4.131  21.561  1.00 14.33 ? 79  LEU L H    1 
ATOM   5816 H HA   . LEU C 3 79  ? 11.892  6.586  20.896  1.00 14.48 ? 79  LEU L HA   1 
ATOM   5817 H HB2  . LEU C 3 79  ? 9.738   5.351  21.077  1.00 17.13 ? 79  LEU L HB2  1 
ATOM   5818 H HB3  . LEU C 3 79  ? 9.714   5.961  22.544  1.00 17.13 ? 79  LEU L HB3  1 
ATOM   5819 H HG   . LEU C 3 79  ? 9.656   8.108  21.528  1.00 21.40 ? 79  LEU L HG   1 
ATOM   5820 H HD11 . LEU C 3 79  ? 8.935   8.383  19.403  1.00 20.27 ? 79  LEU L HD11 1 
ATOM   5821 H HD12 . LEU C 3 79  ? 10.397  7.764  19.466  1.00 20.27 ? 79  LEU L HD12 1 
ATOM   5822 H HD13 . LEU C 3 79  ? 9.154   6.833  19.134  1.00 20.27 ? 79  LEU L HD13 1 
ATOM   5823 H HD21 . LEU C 3 79  ? 7.307   7.920  21.134  1.00 34.24 ? 79  LEU L HD21 1 
ATOM   5824 H HD22 . LEU C 3 79  ? 7.466   6.340  21.097  1.00 34.24 ? 79  LEU L HD22 1 
ATOM   5825 H HD23 . LEU C 3 79  ? 7.723   7.132  22.449  1.00 34.24 ? 79  LEU L HD23 1 
ATOM   5826 N N    . GLU C 3 80  ? 12.374  8.046  22.835  1.00 11.75 ? 80  GLU L N    1 
ATOM   5827 C CA   . GLU C 3 80  ? 12.590  8.874  24.008  1.00 12.31 ? 80  GLU L CA   1 
ATOM   5828 C C    . GLU C 3 80  ? 11.477  9.884  24.154  1.00 14.42 ? 80  GLU L C    1 
ATOM   5829 O O    . GLU C 3 80  ? 10.821  10.235 23.178  1.00 12.68 ? 80  GLU L O    1 
ATOM   5830 C CB   . GLU C 3 80  ? 13.927  9.625  23.945  1.00 12.37 ? 80  GLU L CB   1 
ATOM   5831 C CG   . GLU C 3 80  ? 15.126  8.712  23.761  1.00 14.64 ? 80  GLU L CG   1 
ATOM   5832 C CD   . GLU C 3 80  ? 15.499  8.017  25.071  1.00 17.65 ? 80  GLU L CD   1 
ATOM   5833 O OE1  . GLU C 3 80  ? 14.899  8.321  26.105  1.00 15.41 ? 80  GLU L OE1  1 
ATOM   5834 O OE2  . GLU C 3 80  ? 16.313  7.067  25.079  1.00 19.92 ? 80  GLU L OE2  1 
ATOM   5835 H H    . GLU C 3 80  ? 12.520  8.446  22.088  1.00 14.16 ? 80  GLU L H    1 
ATOM   5836 H HA   . GLU C 3 80  ? 12.614  8.298  24.788  1.00 14.84 ? 80  GLU L HA   1 
ATOM   5837 H HB2  . GLU C 3 80  ? 13.905  10.242 23.197  1.00 14.90 ? 80  GLU L HB2  1 
ATOM   5838 H HB3  . GLU C 3 80  ? 14.051  10.113 24.774  1.00 14.90 ? 80  GLU L HB3  1 
ATOM   5839 H HG2  . GLU C 3 80  ? 14.915  8.032  23.102  1.00 17.63 ? 80  GLU L HG2  1 
ATOM   5840 H HG3  . GLU C 3 80  ? 15.887  9.236  23.464  1.00 17.63 ? 80  GLU L HG3  1 
ATOM   5841 N N    . PRO C 3 81  ? 11.246  10.384 25.372  1.00 12.23 ? 81  PRO L N    1 
ATOM   5842 C CA   . PRO C 3 81  ? 10.194  11.385 25.577  1.00 13.75 ? 81  PRO L CA   1 
ATOM   5843 C C    . PRO C 3 81  ? 10.336  12.604 24.687  1.00 14.47 ? 81  PRO L C    1 
ATOM   5844 O O    . PRO C 3 81  ? 9.313   13.161 24.310  1.00 16.40 ? 81  PRO L O    1 
ATOM   5845 C CB   . PRO C 3 81  ? 10.353  11.738 27.062  1.00 13.52 ? 81  PRO L CB   1 
ATOM   5846 C CG   . PRO C 3 81  ? 11.009  10.498 27.690  1.00 16.16 ? 81  PRO L CG   1 
ATOM   5847 C CD   . PRO C 3 81  ? 11.939  10.010 26.614  1.00 9.40  ? 81  PRO L CD   1 
ATOM   5848 H HA   . PRO C 3 81  ? 9.321   10.990 25.428  1.00 16.56 ? 81  PRO L HA   1 
ATOM   5849 H HB2  . PRO C 3 81  ? 10.921  12.519 27.158  1.00 16.29 ? 81  PRO L HB2  1 
ATOM   5850 H HB3  . PRO C 3 81  ? 9.484   11.910 27.457  1.00 16.29 ? 81  PRO L HB3  1 
ATOM   5851 H HG2  . PRO C 3 81  ? 11.497  10.745 28.491  1.00 19.45 ? 81  PRO L HG2  1 
ATOM   5852 H HG3  . PRO C 3 81  ? 10.336  9.833  27.902  1.00 19.45 ? 81  PRO L HG3  1 
ATOM   5853 H HD2  . PRO C 3 81  ? 12.800  10.452 26.675  1.00 11.35 ? 81  PRO L HD2  1 
ATOM   5854 H HD3  . PRO C 3 81  ? 12.054  9.048  26.668  1.00 11.35 ? 81  PRO L HD3  1 
ATOM   5855 N N    . GLU C 3 82  ? 11.546  13.015 24.305  1.00 13.13 ? 82  GLU L N    1 
ATOM   5856 C CA   . GLU C 3 82  ? 11.721  14.164 23.413  1.00 13.30 ? 82  GLU L CA   1 
ATOM   5857 C C    . GLU C 3 82  ? 11.311  13.859 21.986  1.00 17.57 ? 82  GLU L C    1 
ATOM   5858 O O    . GLU C 3 82  ? 11.406  14.759 21.150  1.00 14.73 ? 82  GLU L O    1 
ATOM   5859 C CB   . GLU C 3 82  ? 13.180  14.658 23.425  1.00 17.25 ? 82  GLU L CB   1 
ATOM   5860 C CG   . GLU C 3 82  ? 14.223  13.643 22.947  1.00 14.64 ? 82  GLU L CG   1 
ATOM   5861 C CD   . GLU C 3 82  ? 15.657  14.237 22.870  1.00 22.41 ? 82  GLU L CD   1 
ATOM   5862 O OE1  . GLU C 3 82  ? 15.817  15.472 22.833  1.00 21.88 ? 82  GLU L OE1  1 
ATOM   5863 O OE2  . GLU C 3 82  ? 16.625  13.471 22.895  1.00 20.71 ? 82  GLU L OE2  1 
ATOM   5864 H H    . GLU C 3 82  ? 12.283  12.645 24.549  1.00 15.82 ? 82  GLU L H    1 
ATOM   5865 H HA   . GLU C 3 82  ? 11.167  14.886 23.750  1.00 16.02 ? 82  GLU L HA   1 
ATOM   5866 H HB2  . GLU C 3 82  ? 13.244  15.433 22.845  1.00 20.76 ? 82  GLU L HB2  1 
ATOM   5867 H HB3  . GLU C 3 82  ? 13.411  14.904 24.334  1.00 20.76 ? 82  GLU L HB3  1 
ATOM   5868 H HG2  . GLU C 3 82  ? 14.242  12.896 23.566  1.00 17.63 ? 82  GLU L HG2  1 
ATOM   5869 H HG3  . GLU C 3 82  ? 13.980  13.333 22.061  1.00 17.63 ? 82  GLU L HG3  1 
ATOM   5870 N N    . ASP C 3 83  ? 10.918  12.627 21.667  1.00 13.96 ? 83  ASP L N    1 
ATOM   5871 C CA   . ASP C 3 83  ? 10.593  12.252 20.303  1.00 12.65 ? 83  ASP L CA   1 
ATOM   5872 C C    . ASP C 3 83  ? 9.103   12.351 20.000  1.00 14.16 ? 83  ASP L C    1 
ATOM   5873 O O    . ASP C 3 83  ? 8.732   12.187 18.826  1.00 11.75 ? 83  ASP L O    1 
ATOM   5874 C CB   . ASP C 3 83  ? 11.029  10.803 20.011  1.00 12.55 ? 83  ASP L CB   1 
ATOM   5875 C CG   . ASP C 3 83  ? 12.509  10.572 20.184  1.00 13.63 ? 83  ASP L CG   1 
ATOM   5876 O OD1  . ASP C 3 83  ? 13.295  11.544 20.081  1.00 15.54 ? 83  ASP L OD1  1 
ATOM   5877 O OD2  . ASP C 3 83  ? 12.900  9.402  20.421  1.00 11.22 ? 83  ASP L OD2  1 
ATOM   5878 H H    . ASP C 3 83  ? 10.832  11.986 22.234  1.00 16.81 ? 83  ASP L H    1 
ATOM   5879 H HA   . ASP C 3 83  ? 11.082  12.846 19.713  1.00 15.24 ? 83  ASP L HA   1 
ATOM   5880 H HB2  . ASP C 3 83  ? 10.563  10.208 20.618  1.00 15.12 ? 83  ASP L HB2  1 
ATOM   5881 H HB3  . ASP C 3 83  ? 10.800  10.587 19.093  1.00 15.12 ? 83  ASP L HB3  1 
ATOM   5882 N N    . PHE C 3 84  ? 8.226   12.589 20.989  1.00 12.41 ? 84  PHE L N    1 
ATOM   5883 C CA   . PHE C 3 84  ? 6.806   12.736 20.659  1.00 13.11 ? 84  PHE L CA   1 
ATOM   5884 C C    . PHE C 3 84  ? 6.648   14.062 19.916  1.00 17.22 ? 84  PHE L C    1 
ATOM   5885 O O    . PHE C 3 84  ? 7.066   15.110 20.422  1.00 16.81 ? 84  PHE L O    1 
ATOM   5886 C CB   . PHE C 3 84  ? 5.929   12.678 21.909  1.00 14.05 ? 84  PHE L CB   1 
ATOM   5887 C CG   . PHE C 3 84  ? 5.983   11.346 22.592  1.00 19.73 ? 84  PHE L CG   1 
ATOM   5888 C CD1  . PHE C 3 84  ? 5.315   10.266 22.070  1.00 15.46 ? 84  PHE L CD1  1 
ATOM   5889 C CD2  . PHE C 3 84  ? 6.667   11.181 23.783  1.00 22.37 ? 84  PHE L CD2  1 
ATOM   5890 C CE1  . PHE C 3 84  ? 5.356   9.040  22.669  1.00 16.10 ? 84  PHE L CE1  1 
ATOM   5891 C CE2  . PHE C 3 84  ? 6.694   9.933  24.417  1.00 27.85 ? 84  PHE L CE2  1 
ATOM   5892 C CZ   . PHE C 3 84  ? 6.041   8.853  23.849  1.00 20.57 ? 84  PHE L CZ   1 
ATOM   5893 H H    . PHE C 3 84  ? 8.423   12.665 21.823  1.00 14.95 ? 84  PHE L H    1 
ATOM   5894 H HA   . PHE C 3 84  ? 6.509   12.003 20.097  1.00 15.80 ? 84  PHE L HA   1 
ATOM   5895 H HB2  . PHE C 3 84  ? 6.232   13.351 22.539  1.00 16.92 ? 84  PHE L HB2  1 
ATOM   5896 H HB3  . PHE C 3 84  ? 5.008   12.849 21.657  1.00 16.92 ? 84  PHE L HB3  1 
ATOM   5897 H HD1  . PHE C 3 84  ? 4.823   10.372 21.288  1.00 18.61 ? 84  PHE L HD1  1 
ATOM   5898 H HD2  . PHE C 3 84  ? 7.112   11.903 24.165  1.00 26.91 ? 84  PHE L HD2  1 
ATOM   5899 H HE1  . PHE C 3 84  ? 4.915   8.321  22.275  1.00 19.38 ? 84  PHE L HE1  1 
ATOM   5900 H HE2  . PHE C 3 84  ? 7.152   9.829  25.220  1.00 33.48 ? 84  PHE L HE2  1 
ATOM   5901 H HZ   . PHE C 3 84  ? 6.064   8.018  24.256  1.00 24.75 ? 84  PHE L HZ   1 
ATOM   5902 N N    . ALA C 3 85  ? 6.134   14.008 18.686  1.00 11.51 ? 85  ALA L N    1 
ATOM   5903 C CA   . ALA C 3 85  ? 6.266   15.068 17.706  1.00 12.25 ? 85  ALA L CA   1 
ATOM   5904 C C    . ALA C 3 85  ? 5.504   14.611 16.465  1.00 13.27 ? 85  ALA L C    1 
ATOM   5905 O O    . ALA C 3 85  ? 4.986   13.488 16.391  1.00 13.18 ? 85  ALA L O    1 
ATOM   5906 C CB   . ALA C 3 85  ? 7.745   15.389 17.355  1.00 12.93 ? 85  ALA L CB   1 
ATOM   5907 H H    . ALA C 3 85  ? 5.687   13.336 18.389  1.00 13.88 ? 85  ALA L H    1 
ATOM   5908 H HA   . ALA C 3 85  ? 5.868   15.882 18.052  1.00 14.76 ? 85  ALA L HA   1 
ATOM   5909 H HB1  . ALA C 3 85  ? 7.767   16.125 16.723  1.00 15.57 ? 85  ALA L HB1  1 
ATOM   5910 H HB2  . ALA C 3 85  ? 8.216   15.636 18.166  1.00 15.57 ? 85  ALA L HB2  1 
ATOM   5911 H HB3  . ALA C 3 85  ? 8.154   14.603 16.961  1.00 15.57 ? 85  ALA L HB3  1 
ATOM   5912 N N    . VAL C 3 86  ? 5.438   15.507 15.509  1.00 12.47 ? 86  VAL L N    1 
ATOM   5913 C CA   . VAL C 3 86  ? 4.925   15.188 14.182  1.00 12.88 ? 86  VAL L CA   1 
ATOM   5914 C C    . VAL C 3 86  ? 6.084   14.913 13.244  1.00 13.12 ? 86  VAL L C    1 
ATOM   5915 O O    . VAL C 3 86  ? 7.081   15.618 13.276  1.00 12.71 ? 86  VAL L O    1 
ATOM   5916 C CB   . VAL C 3 86  ? 4.027   16.312 13.623  1.00 12.66 ? 86  VAL L CB   1 
ATOM   5917 C CG1  . VAL C 3 86  ? 3.573   15.980 12.200  1.00 13.66 ? 86  VAL L CG1  1 
ATOM   5918 C CG2  . VAL C 3 86  ? 2.819   16.526 14.544  1.00 19.76 ? 86  VAL L CG2  1 
ATOM   5919 H H    . VAL C 3 86  ? 5.688   16.326 15.599  1.00 15.03 ? 86  VAL L H    1 
ATOM   5920 H HA   . VAL C 3 86  ? 4.391   14.381 14.255  1.00 15.52 ? 86  VAL L HA   1 
ATOM   5921 H HB   . VAL C 3 86  ? 4.535   17.137 13.588  1.00 15.26 ? 86  VAL L HB   1 
ATOM   5922 H HG11 . VAL C 3 86  ? 2.923   16.642 11.914  1.00 16.45 ? 86  VAL L HG11 1 
ATOM   5923 H HG12 . VAL C 3 86  ? 4.343   15.997 11.611  1.00 16.45 ? 86  VAL L HG12 1 
ATOM   5924 H HG13 . VAL C 3 86  ? 3.171   15.098 12.194  1.00 16.45 ? 86  VAL L HG13 1 
ATOM   5925 H HG21 . VAL C 3 86  ? 2.178   17.099 14.096  1.00 23.77 ? 86  VAL L HG21 1 
ATOM   5926 H HG22 . VAL C 3 86  ? 2.414   15.666 14.739  1.00 23.77 ? 86  VAL L HG22 1 
ATOM   5927 H HG23 . VAL C 3 86  ? 3.119   16.944 15.366  1.00 23.77 ? 86  VAL L HG23 1 
ATOM   5928 N N    . TYR C 3 87  ? 5.933   13.938 12.347  1.00 12.44 ? 87  TYR L N    1 
ATOM   5929 C CA   . TYR C 3 87  ? 6.998   13.547 11.418  1.00 12.10 ? 87  TYR L CA   1 
ATOM   5930 C C    . TYR C 3 87  ? 6.487   13.625 9.985   1.00 11.81 ? 87  TYR L C    1 
ATOM   5931 O O    . TYR C 3 87  ? 5.431   13.081 9.689   1.00 12.83 ? 87  TYR L O    1 
ATOM   5932 C CB   . TYR C 3 87  ? 7.500   12.123 11.727  1.00 11.64 ? 87  TYR L CB   1 
ATOM   5933 C CG   . TYR C 3 87  ? 8.211   12.066 13.020  1.00 10.27 ? 87  TYR L CG   1 
ATOM   5934 C CD1  . TYR C 3 87  ? 7.501   11.939 14.207  1.00 10.53 ? 87  TYR L CD1  1 
ATOM   5935 C CD2  . TYR C 3 87  ? 9.580   12.218 13.085  1.00 10.88 ? 87  TYR L CD2  1 
ATOM   5936 C CE1  . TYR C 3 87  ? 8.144   11.981 15.427  1.00 13.15 ? 87  TYR L CE1  1 
ATOM   5937 C CE2  . TYR C 3 87  ? 10.227  12.188 14.285  1.00 14.30 ? 87  TYR L CE2  1 
ATOM   5938 C CZ   . TYR C 3 87  ? 9.501   12.089 15.456  1.00 12.19 ? 87  TYR L CZ   1 
ATOM   5939 O OH   . TYR C 3 87  ? 10.225  12.131 16.627  1.00 12.90 ? 87  TYR L OH   1 
ATOM   5940 H H    . TYR C 3 87  ? 5.211   13.480 12.255  1.00 14.99 ? 87  TYR L H    1 
ATOM   5941 H HA   . TYR C 3 87  ? 7.741   14.165 11.505  1.00 14.58 ? 87  TYR L HA   1 
ATOM   5942 H HB2  . TYR C 3 87  ? 6.743   11.518 11.768  1.00 14.03 ? 87  TYR L HB2  1 
ATOM   5943 H HB3  . TYR C 3 87  ? 8.112   11.841 11.029  1.00 14.03 ? 87  TYR L HB3  1 
ATOM   5944 H HD1  . TYR C 3 87  ? 6.578   11.825 14.179  1.00 12.70 ? 87  TYR L HD1  1 
ATOM   5945 H HD2  . TYR C 3 87  ? 10.067  12.342 12.302  1.00 13.12 ? 87  TYR L HD2  1 
ATOM   5946 H HE1  . TYR C 3 87  ? 7.658   11.937 16.219  1.00 15.84 ? 87  TYR L HE1  1 
ATOM   5947 H HE2  . TYR C 3 87  ? 11.155  12.234 14.314  1.00 17.23 ? 87  TYR L HE2  1 
ATOM   5948 H HH   . TYR C 3 87  ? 9.706   12.114 17.287  1.00 15.54 ? 87  TYR L HH   1 
ATOM   5949 N N    . TYR C 3 88  ? 7.227   14.290 9.105   1.00 10.34 ? 88  TYR L N    1 
ATOM   5950 C CA   . TYR C 3 88  ? 6.853   14.401 7.704   1.00 12.34 ? 88  TYR L CA   1 
ATOM   5951 C C    . TYR C 3 88  ? 7.875   13.713 6.819   1.00 11.14 ? 88  TYR L C    1 
ATOM   5952 O O    . TYR C 3 88  ? 9.073   13.884 7.022   1.00 13.72 ? 88  TYR L O    1 
ATOM   5953 C CB   . TYR C 3 88  ? 6.786   15.882 7.260   1.00 12.71 ? 88  TYR L CB   1 
ATOM   5954 C CG   . TYR C 3 88  ? 5.725   16.673 7.944   1.00 12.95 ? 88  TYR L CG   1 
ATOM   5955 C CD1  . TYR C 3 88  ? 4.407   16.656 7.474   1.00 13.71 ? 88  TYR L CD1  1 
ATOM   5956 C CD2  . TYR C 3 88  ? 6.028   17.474 9.019   1.00 14.95 ? 88  TYR L CD2  1 
ATOM   5957 C CE1  . TYR C 3 88  ? 3.415   17.390 8.093   1.00 12.10 ? 88  TYR L CE1  1 
ATOM   5958 C CE2  . TYR C 3 88  ? 5.048   18.221 9.634   1.00 15.62 ? 88  TYR L CE2  1 
ATOM   5959 C CZ   . TYR C 3 88  ? 3.740   18.150 9.176   1.00 14.47 ? 88  TYR L CZ   1 
ATOM   5960 O OH   . TYR C 3 88  ? 2.755   18.872 9.756   1.00 17.44 ? 88  TYR L OH   1 
ATOM   5961 H H    . TYR C 3 88  ? 7.962   14.692 9.301   1.00 12.47 ? 88  TYR L H    1 
ATOM   5962 H HA   . TYR C 3 88  ? 5.989   13.974 7.592   1.00 14.87 ? 88  TYR L HA   1 
ATOM   5963 H HB2  . TYR C 3 88  ? 7.638   16.303 7.452   1.00 15.31 ? 88  TYR L HB2  1 
ATOM   5964 H HB3  . TYR C 3 88  ? 6.608   15.913 6.307   1.00 15.31 ? 88  TYR L HB3  1 
ATOM   5965 H HD1  . TYR C 3 88  ? 4.195   16.141 6.730   1.00 16.52 ? 88  TYR L HD1  1 
ATOM   5966 H HD2  . TYR C 3 88  ? 6.902   17.513 9.333   1.00 18.00 ? 88  TYR L HD2  1 
ATOM   5967 H HE1  . TYR C 3 88  ? 2.541   17.366 7.776   1.00 14.58 ? 88  TYR L HE1  1 
ATOM   5968 H HE2  . TYR C 3 88  ? 5.262   18.769 10.354  1.00 18.80 ? 88  TYR L HE2  1 
ATOM   5969 H HH   . TYR C 3 88  ? 3.028   19.200 10.480  1.00 20.98 ? 88  TYR L HH   1 
ATOM   5970 N N    . CYS C 3 89  ? 7.419   13.051 5.760   1.00 9.89  ? 89  CYS L N    1 
ATOM   5971 C CA   . CYS C 3 89  ? 8.325   12.683 4.680   1.00 10.54 ? 89  CYS L CA   1 
ATOM   5972 C C    . CYS C 3 89  ? 8.194   13.655 3.526   1.00 12.77 ? 89  CYS L C    1 
ATOM   5973 O O    . CYS C 3 89  ? 7.261   14.459 3.449   1.00 11.01 ? 89  CYS L O    1 
ATOM   5974 C CB   . CYS C 3 89  ? 8.095   11.244 4.190   1.00 14.60 ? 89  CYS L CB   1 
ATOM   5975 S SG   . CYS C 3 89  ? 6.470   10.948 3.560   1.00 19.09 ? 89  CYS L SG   1 
ATOM   5976 H H    . CYS C 3 89  ? 6.601   12.809 5.648   1.00 11.93 ? 89  CYS L H    1 
ATOM   5977 H HA   . CYS C 3 89  ? 9.233   12.722 5.018   1.00 12.71 ? 89  CYS L HA   1 
ATOM   5978 H HB2  . CYS C 3 89  ? 8.726   11.053 3.478   1.00 17.58 ? 89  CYS L HB2  1 
ATOM   5979 H HB3  . CYS C 3 89  ? 8.238   10.636 4.932   1.00 17.58 ? 89  CYS L HB3  1 
ATOM   5980 N N    . GLN C 3 90  ? 9.192   13.613 2.653   1.00 12.25 ? 90  GLN L N    1 
ATOM   5981 C CA   . GLN C 3 90  ? 9.277   14.557 1.561   1.00 12.54 ? 90  GLN L CA   1 
ATOM   5982 C C    . GLN C 3 90  ? 10.067  13.898 0.451   1.00 12.02 ? 90  GLN L C    1 
ATOM   5983 O O    . GLN C 3 90  ? 11.057  13.192 0.715   1.00 12.25 ? 90  GLN L O    1 
ATOM   5984 C CB   . GLN C 3 90  ? 9.965   15.849 1.987   1.00 12.27 ? 90  GLN L CB   1 
ATOM   5985 C CG   . GLN C 3 90  ? 10.214  16.859 0.869   1.00 12.81 ? 90  GLN L CG   1 
ATOM   5986 C CD   . GLN C 3 90  ? 11.501  17.670 1.071   1.00 12.41 ? 90  GLN L CD   1 
ATOM   5987 O OE1  . GLN C 3 90  ? 12.558  17.134 1.431   1.00 12.35 ? 90  GLN L OE1  1 
ATOM   5988 N NE2  . GLN C 3 90  ? 11.422  18.981 0.777   1.00 14.66 ? 90  GLN L NE2  1 
ATOM   5989 H H    . GLN C 3 90  ? 9.835   13.042 2.677   1.00 14.77 ? 90  GLN L H    1 
ATOM   5990 H HA   . GLN C 3 90  ? 8.390   14.783 1.241   1.00 15.11 ? 90  GLN L HA   1 
ATOM   5991 H HB2  . GLN C 3 90  ? 9.409   16.285 2.652   1.00 14.79 ? 90  GLN L HB2  1 
ATOM   5992 H HB3  . GLN C 3 90  ? 10.827  15.624 2.370   1.00 14.79 ? 90  GLN L HB3  1 
ATOM   5993 H HG2  . GLN C 3 90  ? 10.289  16.385 0.026   1.00 15.43 ? 90  GLN L HG2  1 
ATOM   5994 H HG3  . GLN C 3 90  ? 9.471   17.482 0.834   1.00 15.43 ? 90  GLN L HG3  1 
ATOM   5995 H HE21 . GLN C 3 90  ? 10.681  19.314 0.495   1.00 17.66 ? 90  GLN L HE21 1 
ATOM   5996 H HE22 . GLN C 3 90  ? 12.112  19.485 0.871   1.00 17.66 ? 90  GLN L HE22 1 
ATOM   5997 N N    . GLN C 3 91  ? 9.643   14.116 -0.784  1.00 10.61 ? 91  GLN L N    1 
ATOM   5998 C CA   . GLN C 3 91  ? 10.471  13.754 -1.928  1.00 11.96 ? 91  GLN L CA   1 
ATOM   5999 C C    . GLN C 3 91  ? 11.155  15.020 -2.423  1.00 11.43 ? 91  GLN L C    1 
ATOM   6000 O O    . GLN C 3 91  ? 10.552  16.092 -2.453  1.00 11.12 ? 91  GLN L O    1 
ATOM   6001 C CB   . GLN C 3 91  ? 9.688   13.091 -3.055  1.00 13.32 ? 91  GLN L CB   1 
ATOM   6002 C CG   . GLN C 3 91  ? 8.757   13.896 -3.896  1.00 13.05 ? 91  GLN L CG   1 
ATOM   6003 C CD   . GLN C 3 91  ? 9.464   14.851 -4.864  1.00 10.94 ? 91  GLN L CD   1 
ATOM   6004 O OE1  . GLN C 3 91  ? 10.567  14.551 -5.340  1.00 10.20 ? 91  GLN L OE1  1 
ATOM   6005 N NE2  . GLN C 3 91  ? 8.773   15.914 -5.280  1.00 13.28 ? 91  GLN L NE2  1 
ATOM   6006 H H    . GLN C 3 91  ? 8.885   14.469 -0.986  1.00 12.79 ? 91  GLN L H    1 
ATOM   6007 H HA   . GLN C 3 91  ? 11.132  13.098 -1.657  1.00 14.41 ? 91  GLN L HA   1 
ATOM   6008 H HB2  . GLN C 3 91  ? 10.336  12.706 -3.666  1.00 16.04 ? 91  GLN L HB2  1 
ATOM   6009 H HB3  . GLN C 3 91  ? 9.150   12.390 -2.656  1.00 16.04 ? 91  GLN L HB3  1 
ATOM   6010 H HG2  . GLN C 3 91  ? 8.212   13.292 -4.423  1.00 15.72 ? 91  GLN L HG2  1 
ATOM   6011 H HG3  . GLN C 3 91  ? 8.194   14.430 -3.314  1.00 15.72 ? 91  GLN L HG3  1 
ATOM   6012 H HE21 . GLN C 3 91  ? 7.968   16.038 -5.004  1.00 16.00 ? 91  GLN L HE21 1 
ATOM   6013 H HE22 . GLN C 3 91  ? 9.132   16.475 -5.824  1.00 16.00 ? 91  GLN L HE22 1 
ATOM   6014 N N    . TYR C 3 92  ? 12.454  14.931 -2.730  1.00 11.86 ? 92  TYR L N    1 
ATOM   6015 C CA   . TYR C 3 92  ? 13.197  16.103 -3.184  1.00 11.90 ? 92  TYR L CA   1 
ATOM   6016 C C    . TYR C 3 92  ? 13.967  15.844 -4.476  1.00 10.19 ? 92  TYR L C    1 
ATOM   6017 O O    . TYR C 3 92  ? 14.897  16.589 -4.815  1.00 11.40 ? 92  TYR L O    1 
ATOM   6018 C CB   . TYR C 3 92  ? 14.126  16.621 -2.094  1.00 11.54 ? 92  TYR L CB   1 
ATOM   6019 C CG   . TYR C 3 92  ? 15.083  15.586 -1.549  1.00 11.10 ? 92  TYR L CG   1 
ATOM   6020 C CD1  . TYR C 3 92  ? 16.261  15.301 -2.199  1.00 11.32 ? 92  TYR L CD1  1 
ATOM   6021 C CD2  . TYR C 3 92  ? 14.765  14.836 -0.418  1.00 14.14 ? 92  TYR L CD2  1 
ATOM   6022 C CE1  . TYR C 3 92  ? 17.177  14.342 -1.705  1.00 9.75  ? 92  TYR L CE1  1 
ATOM   6023 C CE2  . TYR C 3 92  ? 15.668  13.843 0.081   1.00 11.13 ? 92  TYR L CE2  1 
ATOM   6024 C CZ   . TYR C 3 92  ? 16.851  13.620 -0.570  1.00 13.16 ? 92  TYR L CZ   1 
ATOM   6025 O OH   . TYR C 3 92  ? 17.693  12.662 -0.092  1.00 14.30 ? 92  TYR L OH   1 
ATOM   6026 H H    . TYR C 3 92  ? 12.919  14.209 -2.682  1.00 14.29 ? 92  TYR L H    1 
ATOM   6027 H HA   . TYR C 3 92  ? 12.558  16.807 -3.378  1.00 14.34 ? 92  TYR L HA   1 
ATOM   6028 H HB2  . TYR C 3 92  ? 14.655  17.349 -2.457  1.00 13.91 ? 92  TYR L HB2  1 
ATOM   6029 H HB3  . TYR C 3 92  ? 13.587  16.940 -1.353  1.00 13.91 ? 92  TYR L HB3  1 
ATOM   6030 H HD1  . TYR C 3 92  ? 16.462  15.752 -2.987  1.00 13.64 ? 92  TYR L HD1  1 
ATOM   6031 H HD2  . TYR C 3 92  ? 13.957  14.983 0.017   1.00 17.03 ? 92  TYR L HD2  1 
ATOM   6032 H HE1  . TYR C 3 92  ? 17.988  14.198 -2.138  1.00 11.76 ? 92  TYR L HE1  1 
ATOM   6033 H HE2  . TYR C 3 92  ? 15.452  13.353 0.842   1.00 13.41 ? 92  TYR L HE2  1 
ATOM   6034 H HH   . TYR C 3 92  ? 18.428  12.698 -0.497  1.00 17.23 ? 92  TYR L HH   1 
ATOM   6035 N N    . GLY C 3 93  ? 13.534  14.858 -5.247  1.00 9.87  ? 93  GLY L N    1 
ATOM   6036 C CA   . GLY C 3 93  ? 14.154  14.584 -6.531  1.00 9.51  ? 93  GLY L CA   1 
ATOM   6037 C C    . GLY C 3 93  ? 13.652  15.412 -7.682  1.00 12.94 ? 93  GLY L C    1 
ATOM   6038 O O    . GLY C 3 93  ? 14.340  15.519 -8.710  1.00 12.12 ? 93  GLY L O    1 
ATOM   6039 H H    . GLY C 3 93  ? 12.882  14.333 -5.050  1.00 11.90 ? 93  GLY L H    1 
ATOM   6040 H HA2  . GLY C 3 93  ? 15.108  14.741 -6.452  1.00 11.47 ? 93  GLY L HA2  1 
ATOM   6041 H HA3  . GLY C 3 93  ? 14.004  13.652 -6.752  1.00 11.47 ? 93  GLY L HA3  1 
ATOM   6042 N N    . GLN C 3 94  ? 12.514  16.065 -7.512  1.00 12.62 ? 94  GLN L N    1 
ATOM   6043 C CA   . GLN C 3 94  ? 11.987  16.883 -8.588  1.00 13.24 ? 94  GLN L CA   1 
ATOM   6044 C C    . GLN C 3 94  ? 11.029  17.914 -8.039  1.00 13.25 ? 94  GLN L C    1 
ATOM   6045 O O    . GLN C 3 94  ? 10.421  17.716 -6.989  1.00 12.61 ? 94  GLN L O    1 
ATOM   6046 C CB   . GLN C 3 94  ? 11.315  15.982 -9.628  1.00 15.20 ? 94  GLN L CB   1 
ATOM   6047 C CG   . GLN C 3 94  ? 10.084  15.282 -9.202  1.00 15.56 ? 94  GLN L CG   1 
ATOM   6048 C CD   . GLN C 3 94  ? 9.705   14.157 -10.131 1.00 23.42 ? 94  GLN L CD   1 
ATOM   6049 O OE1  . GLN C 3 94  ? 10.378  13.113 -10.190 1.00 20.15 ? 94  GLN L OE1  1 
ATOM   6050 N NE2  . GLN C 3 94  ? 8.696   14.406 -10.954 1.00 21.23 ? 94  GLN L NE2  1 
ATOM   6051 H H    . GLN C 3 94  ? 12.037  16.052 -6.796  1.00 15.20 ? 94  GLN L H    1 
ATOM   6052 H HA   . GLN C 3 94  ? 12.701  17.386 -9.012  1.00 15.95 ? 94  GLN L HA   1 
ATOM   6053 H HB2  . GLN C 3 94  ? 11.079  16.529 -10.393 1.00 18.30 ? 94  GLN L HB2  1 
ATOM   6054 H HB3  . GLN C 3 94  ? 11.952  15.299 -9.891  1.00 18.30 ? 94  GLN L HB3  1 
ATOM   6055 H HG2  . GLN C 3 94  ? 10.223  14.908 -8.318  1.00 18.73 ? 94  GLN L HG2  1 
ATOM   6056 H HG3  . GLN C 3 94  ? 9.350   15.916 -9.183  1.00 18.73 ? 94  GLN L HG3  1 
ATOM   6057 H HE21 . GLN C 3 94  ? 8.304   15.172 -10.934 1.00 25.54 ? 94  GLN L HE21 1 
ATOM   6058 H HE22 . GLN C 3 94  ? 8.433   13.803 -11.508 1.00 25.54 ? 94  GLN L HE22 1 
ATOM   6059 N N    . SER C 3 95  ? 10.911  19.009 -8.763  1.00 10.58 ? 95  SER L N    1 
ATOM   6060 C CA   . SER C 3 95  ? 9.883   19.996 -8.446  1.00 11.21 ? 95  SER L CA   1 
ATOM   6061 C C    . SER C 3 95  ? 8.524   19.575 -9.028  1.00 14.91 ? 95  SER L C    1 
ATOM   6062 O O    . SER C 3 95  ? 8.459   18.863 -10.040 1.00 15.28 ? 95  SER L O    1 
ATOM   6063 C CB   . SER C 3 95  ? 10.253  21.358 -9.006  1.00 12.45 ? 95  SER L CB   1 
ATOM   6064 O OG   . SER C 3 95  ? 10.213  21.446 -10.432 1.00 13.21 ? 95  SER L OG   1 
ATOM   6065 H H    . SER C 3 95  ? 11.407  19.209 -9.437  1.00 12.75 ? 95  SER L H    1 
ATOM   6066 H HA   . SER C 3 95  ? 9.802   20.066 -7.482  1.00 13.52 ? 95  SER L HA   1 
ATOM   6067 H HB2  . SER C 3 95  ? 9.631   22.010 -8.646  1.00 15.00 ? 95  SER L HB2  1 
ATOM   6068 H HB3  . SER C 3 95  ? 11.155  21.566 -8.717  1.00 15.00 ? 95  SER L HB3  1 
ATOM   6069 H HG   . SER C 3 95  ? 10.518  22.188 -10.682 1.00 15.92 ? 95  SER L HG   1 
ATOM   6070 N N    . PRO C 3 96  ? 7.432   19.946 -8.391  1.00 12.59 ? 96  PRO L N    1 
ATOM   6071 C CA   . PRO C 3 96  ? 7.322   20.602 -7.091  1.00 12.03 ? 96  PRO L CA   1 
ATOM   6072 C C    . PRO C 3 96  ? 7.858   19.674 -6.028  1.00 11.50 ? 96  PRO L C    1 
ATOM   6073 O O    . PRO C 3 96  ? 7.557   18.471 -6.027  1.00 13.35 ? 96  PRO L O    1 
ATOM   6074 C CB   . PRO C 3 96  ? 5.800   20.854 -6.924  1.00 12.05 ? 96  PRO L CB   1 
ATOM   6075 C CG   . PRO C 3 96  ? 5.142   19.851 -7.820  1.00 16.67 ? 96  PRO L CG   1 
ATOM   6076 C CD   . PRO C 3 96  ? 6.109   19.697 -8.993  1.00 15.93 ? 96  PRO L CD   1 
ATOM   6077 H HA   . PRO C 3 96  ? 7.769   21.463 -7.082  1.00 14.50 ? 96  PRO L HA   1 
ATOM   6078 H HB2  . PRO C 3 96  ? 5.542   20.715 -5.999  1.00 14.52 ? 96  PRO L HB2  1 
ATOM   6079 H HB3  . PRO C 3 96  ? 5.583   21.759 -7.197  1.00 14.52 ? 96  PRO L HB3  1 
ATOM   6080 H HG2  . PRO C 3 96  ? 5.027   19.010 -7.351  1.00 20.06 ? 96  PRO L HG2  1 
ATOM   6081 H HG3  . PRO C 3 96  ? 4.282   20.185 -8.119  1.00 20.06 ? 96  PRO L HG3  1 
ATOM   6082 H HD2  . PRO C 3 96  ? 6.062   18.801 -9.362  1.00 19.18 ? 96  PRO L HD2  1 
ATOM   6083 H HD3  . PRO C 3 96  ? 5.917   20.350 -9.684  1.00 19.18 ? 96  PRO L HD3  1 
ATOM   6084 N N    . TRP C 3 97  ? 8.638   20.220 -5.096  1.00 11.58 ? 97  TRP L N    1 
ATOM   6085 C CA   . TRP C 3 97  ? 9.027   19.473 -3.901  1.00 13.35 ? 97  TRP L CA   1 
ATOM   6086 C C    . TRP C 3 97  ? 7.770   19.185 -3.102  1.00 12.38 ? 97  TRP L C    1 
ATOM   6087 O O    . TRP C 3 97  ? 6.957   20.095 -2.902  1.00 15.88 ? 97  TRP L O    1 
ATOM   6088 C CB   . TRP C 3 97  ? 9.991   20.304 -3.061  1.00 10.06 ? 97  TRP L CB   1 
ATOM   6089 C CG   . TRP C 3 97  ? 11.397  20.387 -3.672  1.00 11.31 ? 97  TRP L CG   1 
ATOM   6090 C CD1  . TRP C 3 97  ? 12.476  19.657 -3.298  1.00 11.02 ? 97  TRP L CD1  1 
ATOM   6091 C CD2  . TRP C 3 97  ? 11.857  21.268 -4.694  1.00 10.03 ? 97  TRP L CD2  1 
ATOM   6092 N NE1  . TRP C 3 97  ? 13.555  19.957 -4.042  1.00 11.16 ? 97  TRP L NE1  1 
ATOM   6093 C CE2  . TRP C 3 97  ? 13.211  20.947 -4.927  1.00 9.72  ? 97  TRP L CE2  1 
ATOM   6094 C CE3  . TRP C 3 97  ? 11.246  22.229 -5.504  1.00 12.79 ? 97  TRP L CE3  1 
ATOM   6095 C CZ2  . TRP C 3 97  ? 13.999  21.621 -5.865  1.00 11.38 ? 97  TRP L CZ2  1 
ATOM   6096 C CZ3  . TRP C 3 97  ? 12.061  22.914 -6.476  1.00 10.67 ? 97  TRP L CZ3  1 
ATOM   6097 C CH2  . TRP C 3 97  ? 13.406  22.586 -6.637  1.00 11.70 ? 97  TRP L CH2  1 
ATOM   6098 H H    . TRP C 3 97  ? 8.955   21.019 -5.132  1.00 13.96 ? 97  TRP L H    1 
ATOM   6099 H HA   . TRP C 3 97  ? 9.473   18.646 -4.140  1.00 16.08 ? 97  TRP L HA   1 
ATOM   6100 H HB2  . TRP C 3 97  ? 9.644   21.207 -2.984  1.00 12.14 ? 97  TRP L HB2  1 
ATOM   6101 H HB3  . TRP C 3 97  ? 10.069  19.903 -2.182  1.00 12.14 ? 97  TRP L HB3  1 
ATOM   6102 H HD1  . TRP C 3 97  ? 12.471  19.027 -2.614  1.00 13.28 ? 97  TRP L HD1  1 
ATOM   6103 H HE1  . TRP C 3 97  ? 14.330  19.590 -3.974  1.00 13.46 ? 97  TRP L HE1  1 
ATOM   6104 H HE3  . TRP C 3 97  ? 10.340  22.421 -5.419  1.00 15.41 ? 97  TRP L HE3  1 
ATOM   6105 H HZ2  . TRP C 3 97  ? 14.902  21.420 -5.963  1.00 13.72 ? 97  TRP L HZ2  1 
ATOM   6106 H HZ3  . TRP C 3 97  ? 11.685  23.582 -7.001  1.00 12.86 ? 97  TRP L HZ3  1 
ATOM   6107 H HH2  . TRP C 3 97  ? 13.910  23.030 -7.279  1.00 14.10 ? 97  TRP L HH2  1 
ATOM   6108 N N    . THR C 3 98  ? 7.527   17.914 -2.746  1.00 11.01 ? 98  THR L N    1 
ATOM   6109 C CA   . THR C 3 98  ? 6.264   17.571 -2.092  1.00 10.66 ? 98  THR L CA   1 
ATOM   6110 C C    . THR C 3 98  ? 6.484   16.842 -0.772  1.00 14.27 ? 98  THR L C    1 
ATOM   6111 O O    . THR C 3 98  ? 7.495   16.184 -0.568  1.00 12.68 ? 98  THR L O    1 
ATOM   6112 C CB   . THR C 3 98  ? 5.372   16.751 -3.011  1.00 16.59 ? 98  THR L CB   1 
ATOM   6113 O OG1  . THR C 3 98  ? 6.131   15.721 -3.629  1.00 14.26 ? 98  THR L OG1  1 
ATOM   6114 C CG2  . THR C 3 98  ? 4.847   17.617 -4.098  1.00 15.67 ? 98  THR L CG2  1 
ATOM   6115 H H    . THR C 3 98  ? 8.066   17.255 -2.870  1.00 13.27 ? 98  THR L H    1 
ATOM   6116 H HA   . THR C 3 98  ? 5.804   18.395 -1.867  1.00 12.85 ? 98  THR L HA   1 
ATOM   6117 H HB   . THR C 3 98  ? 4.645   16.371 -2.493  1.00 19.97 ? 98  THR L HB   1 
ATOM   6118 H HG1  . THR C 3 98  ? 5.647   15.287 -4.161  1.00 17.18 ? 98  THR L HG1  1 
ATOM   6119 H HG21 . THR C 3 98  ? 4.276   17.101 -4.688  1.00 18.86 ? 98  THR L HG21 1 
ATOM   6120 H HG22 . THR C 3 98  ? 4.332   18.348 -3.721  1.00 18.86 ? 98  THR L HG22 1 
ATOM   6121 H HG23 . THR C 3 98  ? 5.582   17.984 -4.614  1.00 18.86 ? 98  THR L HG23 1 
ATOM   6122 N N    . PHE C 3 99  ? 5.493   16.930 0.103   1.00 13.72 ? 99  PHE L N    1 
ATOM   6123 C CA   . PHE C 3 99  ? 5.538   16.372 1.450   1.00 14.60 ? 99  PHE L CA   1 
ATOM   6124 C C    . PHE C 3 99  ? 4.346   15.459 1.699   1.00 15.91 ? 99  PHE L C    1 
ATOM   6125 O O    . PHE C 3 99  ? 3.255   15.692 1.178   1.00 13.10 ? 99  PHE L O    1 
ATOM   6126 C CB   . PHE C 3 99  ? 5.476   17.441 2.556   1.00 13.14 ? 99  PHE L CB   1 
ATOM   6127 C CG   . PHE C 3 99  ? 6.626   18.400 2.580   1.00 11.90 ? 99  PHE L CG   1 
ATOM   6128 C CD1  . PHE C 3 99  ? 6.674   19.506 1.781   1.00 15.12 ? 99  PHE L CD1  1 
ATOM   6129 C CD2  . PHE C 3 99  ? 7.686   18.159 3.438   1.00 11.36 ? 99  PHE L CD2  1 
ATOM   6130 C CE1  . PHE C 3 99  ? 7.772   20.386 1.815   1.00 13.00 ? 99  PHE L CE1  1 
ATOM   6131 C CE2  . PHE C 3 99  ? 8.755   19.009 3.496   1.00 12.41 ? 99  PHE L CE2  1 
ATOM   6132 C CZ   . PHE C 3 99  ? 8.797   20.148 2.680   1.00 15.37 ? 99  PHE L CZ   1 
ATOM   6133 H H    . PHE C 3 99  ? 4.749   17.327 -0.066  1.00 16.52 ? 99  PHE L H    1 
ATOM   6134 H HA   . PHE C 3 99  ? 6.373   15.882 1.509   1.00 17.58 ? 99  PHE L HA   1 
ATOM   6135 H HB2  . PHE C 3 99  ? 4.667   17.961 2.433   1.00 15.83 ? 99  PHE L HB2  1 
ATOM   6136 H HB3  . PHE C 3 99  ? 5.455   16.992 3.415   1.00 15.83 ? 99  PHE L HB3  1 
ATOM   6137 H HD1  . PHE C 3 99  ? 5.968   19.682 1.202   1.00 18.21 ? 99  PHE L HD1  1 
ATOM   6138 H HD2  . PHE C 3 99  ? 7.670   17.407 3.985   1.00 13.70 ? 99  PHE L HD2  1 
ATOM   6139 H HE1  . PHE C 3 99  ? 7.797   21.124 1.251   1.00 15.66 ? 99  PHE L HE1  1 
ATOM   6140 H HE2  . PHE C 3 99  ? 9.457   18.831 4.079   1.00 14.96 ? 99  PHE L HE2  1 
ATOM   6141 H HZ   . PHE C 3 99  ? 9.517   20.735 2.729   1.00 18.51 ? 99  PHE L HZ   1 
ATOM   6142 N N    . GLY C 3 100 ? 4.550   14.467 2.564   1.00 11.77 ? 100 GLY L N    1 
ATOM   6143 C CA   . GLY C 3 100 ? 3.461   13.741 3.168   1.00 16.85 ? 100 GLY L CA   1 
ATOM   6144 C C    . GLY C 3 100 ? 2.660   14.629 4.096   1.00 15.64 ? 100 GLY L C    1 
ATOM   6145 O O    . GLY C 3 100 ? 3.074   15.719 4.480   1.00 13.56 ? 100 GLY L O    1 
ATOM   6146 H H    . GLY C 3 100 ? 5.326   14.197 2.816   1.00 14.19 ? 100 GLY L H    1 
ATOM   6147 H HA2  . GLY C 3 100 ? 2.872   13.402 2.476   1.00 20.29 ? 100 GLY L HA2  1 
ATOM   6148 H HA3  . GLY C 3 100 ? 3.811   12.993 3.678   1.00 20.29 ? 100 GLY L HA3  1 
ATOM   6149 N N    . GLN C 3 101 ? 1.500   14.107 4.503   1.00 14.87 ? 101 GLN L N    1 
ATOM   6150 C CA   . GLN C 3 101 ? 0.569   14.832 5.354   1.00 19.07 ? 101 GLN L CA   1 
ATOM   6151 C C    . GLN C 3 101 ? 0.937   14.766 6.821   1.00 14.59 ? 101 GLN L C    1 
ATOM   6152 O O    . GLN C 3 101 ? 0.260   15.421 7.623   1.00 15.68 ? 101 GLN L O    1 
ATOM   6153 C CB   . GLN C 3 101 ? -0.813  14.249 5.127   1.00 21.02 ? 101 GLN L CB   1 
ATOM   6154 C CG   . GLN C 3 101 ? -1.176  13.016 5.971   1.00 25.95 ? 101 GLN L CG   1 
ATOM   6155 C CD   . GLN C 3 101 ? -0.724  11.700 5.356   1.00 25.97 ? 101 GLN L CD   1 
ATOM   6156 O OE1  . GLN C 3 101 ? 0.025   11.656 4.357   1.00 20.47 ? 101 GLN L OE1  1 
ATOM   6157 N NE2  . GLN C 3 101 ? -1.188  10.605 5.955   1.00 30.67 ? 101 GLN L NE2  1 
ATOM   6158 H H    . GLN C 3 101 ? 1.229   13.318 4.293   1.00 17.91 ? 101 GLN L H    1 
ATOM   6159 H HA   . GLN C 3 101 ? 0.556   15.773 5.118   1.00 22.94 ? 101 GLN L HA   1 
ATOM   6160 H HB2  . GLN C 3 101 ? -1.467  14.936 5.329   1.00 25.29 ? 101 GLN L HB2  1 
ATOM   6161 H HB3  . GLN C 3 101 ? -0.882  13.989 4.196   1.00 25.29 ? 101 GLN L HB3  1 
ATOM   6162 H HG2  . GLN C 3 101 ? -0.754  13.097 6.840   1.00 31.20 ? 101 GLN L HG2  1 
ATOM   6163 H HG3  . GLN C 3 101 ? -2.140  12.980 6.072   1.00 31.20 ? 101 GLN L HG3  1 
ATOM   6164 H HE21 . GLN C 3 101 ? -1.705  10.675 6.639   1.00 36.87 ? 101 GLN L HE21 1 
ATOM   6165 H HE22 . GLN C 3 101 ? -0.971  9.828  5.658   1.00 36.87 ? 101 GLN L HE22 1 
ATOM   6166 N N    . GLY C 3 102 ? 1.953   13.987 7.191   1.00 14.50 ? 102 GLY L N    1 
ATOM   6167 C CA   . GLY C 3 102 ? 2.384   13.956 8.572   1.00 13.56 ? 102 GLY L CA   1 
ATOM   6168 C C    . GLY C 3 102 ? 1.838   12.777 9.348   1.00 13.36 ? 102 GLY L C    1 
ATOM   6169 O O    . GLY C 3 102 ? 0.699   12.342 9.141   1.00 14.82 ? 102 GLY L O    1 
ATOM   6170 H H    . GLY C 3 102 ? 2.398   13.476 6.663   1.00 17.46 ? 102 GLY L H    1 
ATOM   6171 H HA2  . GLY C 3 102 ? 3.353   13.912 8.600   1.00 16.34 ? 102 GLY L HA2  1 
ATOM   6172 H HA3  . GLY C 3 102 ? 2.092   14.769 9.014   1.00 16.34 ? 102 GLY L HA3  1 
ATOM   6173 N N    . THR C 3 103 ? 2.678   12.255 10.241  1.00 13.20 ? 103 THR L N    1 
ATOM   6174 C CA   . THR C 3 103 ? 2.310   11.250 11.229  1.00 14.50 ? 103 THR L CA   1 
ATOM   6175 C C    . THR C 3 103 ? 2.644   11.795 12.615  1.00 14.34 ? 103 THR L C    1 
ATOM   6176 O O    . THR C 3 103 ? 3.787   12.207 12.870  1.00 12.17 ? 103 THR L O    1 
ATOM   6177 C CB   . THR C 3 103 ? 3.049   9.910  11.034  1.00 12.59 ? 103 THR L CB   1 
ATOM   6178 O OG1  . THR C 3 103 ? 2.712   9.300  9.791   1.00 16.05 ? 103 THR L OG1  1 
ATOM   6179 C CG2  . THR C 3 103 ? 2.781   8.959  12.216  1.00 15.10 ? 103 THR L CG2  1 
ATOM   6180 H H    . THR C 3 103 ? 3.506   12.480 10.293  1.00 15.90 ? 103 THR L H    1 
ATOM   6181 H HA   . THR C 3 103 ? 1.359   11.077 11.148  1.00 17.46 ? 103 THR L HA   1 
ATOM   6182 H HB   . THR C 3 103 ? 4.003   10.084 11.009  1.00 15.16 ? 103 THR L HB   1 
ATOM   6183 H HG1  . THR C 3 103 ? 1.877   9.269  9.703   1.00 19.32 ? 103 THR L HG1  1 
ATOM   6184 H HG21 . THR C 3 103 ? 2.957   8.043  11.951  1.00 18.18 ? 103 THR L HG21 1 
ATOM   6185 H HG22 . THR C 3 103 ? 3.357   9.188  12.963  1.00 18.18 ? 103 THR L HG22 1 
ATOM   6186 H HG23 . THR C 3 103 ? 1.856   9.033  12.498  1.00 18.18 ? 103 THR L HG23 1 
ATOM   6187 N N    . LYS C 3 104 ? 1.641   11.803 13.492  1.00 12.02 ? 104 LYS L N    1 
ATOM   6188 C CA   . LYS C 3 104 ? 1.826   12.257 14.865  1.00 13.25 ? 104 LYS L CA   1 
ATOM   6189 C C    . LYS C 3 104 ? 2.235   11.046 15.685  1.00 15.05 ? 104 LYS L C    1 
ATOM   6190 O O    . LYS C 3 104 ? 1.507   10.035 15.715  1.00 16.70 ? 104 LYS L O    1 
ATOM   6191 C CB   . LYS C 3 104 ? 0.515   12.818 15.379  1.00 15.00 ? 104 LYS L CB   1 
ATOM   6192 C CG   . LYS C 3 104 ? 0.301   12.851 16.895  1.00 24.27 ? 104 LYS L CG   1 
ATOM   6193 C CD   . LYS C 3 104 ? -0.566  14.046 17.205  1.00 22.59 ? 104 LYS L CD   1 
ATOM   6194 C CE   . LYS C 3 104 ? -0.563  14.453 18.647  1.00 25.60 ? 104 LYS L CE   1 
ATOM   6195 N NZ   . LYS C 3 104 ? -1.931  14.798 19.121  1.00 26.69 ? 104 LYS L NZ   1 
ATOM   6196 H H    . LYS C 3 104 ? 0.839   11.547 13.313  1.00 14.48 ? 104 LYS L H    1 
ATOM   6197 H HA   . LYS C 3 104 ? 2.511   12.941 14.928  1.00 15.96 ? 104 LYS L HA   1 
ATOM   6198 H HB2  . LYS C 3 104 ? 0.442   13.734 15.067  1.00 18.07 ? 104 LYS L HB2  1 
ATOM   6199 H HB3  . LYS C 3 104 ? -0.203  12.283 15.007  1.00 18.07 ? 104 LYS L HB3  1 
ATOM   6200 H HG2  . LYS C 3 104 ? -0.148  12.043 17.190  1.00 29.19 ? 104 LYS L HG2  1 
ATOM   6201 H HG3  . LYS C 3 104 ? 1.151   12.944 17.353  1.00 29.19 ? 104 LYS L HG3  1 
ATOM   6202 H HD2  . LYS C 3 104 ? -0.250  14.802 16.687  1.00 27.16 ? 104 LYS L HD2  1 
ATOM   6203 H HD3  . LYS C 3 104 ? -1.481  13.837 16.962  1.00 27.16 ? 104 LYS L HD3  1 
ATOM   6204 H HE2  . LYS C 3 104 ? -0.230  13.719 19.187  1.00 30.78 ? 104 LYS L HE2  1 
ATOM   6205 H HE3  . LYS C 3 104 ? 0.004   15.231 18.760  1.00 30.78 ? 104 LYS L HE3  1 
ATOM   6206 H HZ1  . LYS C 3 104 ? -1.909  15.017 19.983  1.00 32.09 ? 104 LYS L HZ1  1 
ATOM   6207 H HZ2  . LYS C 3 104 ? -2.249  15.488 18.656  1.00 32.09 ? 104 LYS L HZ2  1 
ATOM   6208 H HZ3  . LYS C 3 104 ? -2.476  14.102 19.014  1.00 32.09 ? 104 LYS L HZ3  1 
ATOM   6209 N N    . VAL C 3 105 ? 3.318   11.174 16.421  1.00 14.33 ? 105 VAL L N    1 
ATOM   6210 C CA   . VAL C 3 105 ? 3.717   10.181 17.406  1.00 13.46 ? 105 VAL L CA   1 
ATOM   6211 C C    . VAL C 3 105 ? 3.356   10.743 18.771  1.00 11.99 ? 105 VAL L C    1 
ATOM   6212 O O    . VAL C 3 105 ? 3.931   11.755 19.210  1.00 12.69 ? 105 VAL L O    1 
ATOM   6213 C CB   . VAL C 3 105 ? 5.210   9.838  17.311  1.00 14.08 ? 105 VAL L CB   1 
ATOM   6214 C CG1  . VAL C 3 105 ? 5.576   8.748  18.339  1.00 15.82 ? 105 VAL L CG1  1 
ATOM   6215 C CG2  . VAL C 3 105 ? 5.598   9.364  15.910  1.00 14.24 ? 105 VAL L CG2  1 
ATOM   6216 H H    . VAL C 3 105 ? 3.855   11.844 16.371  1.00 17.26 ? 105 VAL L H    1 
ATOM   6217 H HA   . VAL C 3 105 ? 3.219   9.361  17.260  1.00 16.22 ? 105 VAL L HA   1 
ATOM   6218 H HB   . VAL C 3 105 ? 5.710   10.647 17.503  1.00 16.96 ? 105 VAL L HB   1 
ATOM   6219 H HG11 . VAL C 3 105 ? 6.522   8.548  18.264  1.00 19.05 ? 105 VAL L HG11 1 
ATOM   6220 H HG12 . VAL C 3 105 ? 5.376   9.074  19.230  1.00 19.05 ? 105 VAL L HG12 1 
ATOM   6221 H HG13 . VAL C 3 105 ? 5.054   7.952  18.153  1.00 19.05 ? 105 VAL L HG13 1 
ATOM   6222 H HG21 . VAL C 3 105 ? 6.556   9.213  15.881  1.00 17.15 ? 105 VAL L HG21 1 
ATOM   6223 H HG22 . VAL C 3 105 ? 5.127   8.539  15.713  1.00 17.15 ? 105 VAL L HG22 1 
ATOM   6224 H HG23 . VAL C 3 105 ? 5.351   10.047 15.266  1.00 17.15 ? 105 VAL L HG23 1 
ATOM   6225 N N    . GLU C 3 106 ? 2.373   10.110 19.415  1.00 12.64 ? 106 GLU L N    1 
ATOM   6226 C CA   . GLU C 3 106 ? 1.776   10.539 20.671  1.00 12.68 ? 106 GLU L CA   1 
ATOM   6227 C C    . GLU C 3 106 ? 2.023   9.494  21.754  1.00 14.91 ? 106 GLU L C    1 
ATOM   6228 O O    . GLU C 3 106 ? 2.411   8.344  21.479  1.00 13.36 ? 106 GLU L O    1 
ATOM   6229 C CB   . GLU C 3 106 ? 0.254   10.755 20.523  1.00 14.84 ? 106 GLU L CB   1 
ATOM   6230 C CG   . GLU C 3 106 ? -0.487  9.449  20.530  1.00 16.61 ? 106 GLU L CG   1 
ATOM   6231 C CD   . GLU C 3 106 ? -1.981  9.568  20.490  1.00 20.44 ? 106 GLU L CD   1 
ATOM   6232 O OE1  . GLU C 3 106 ? -2.519  10.699 20.446  1.00 23.37 ? 106 GLU L OE1  1 
ATOM   6233 O OE2  . GLU C 3 106 ? -2.620  8.500  20.510  1.00 19.38 ? 106 GLU L OE2  1 
ATOM   6234 H H    . GLU C 3 106 ? 2.017   9.384  19.122  1.00 15.23 ? 106 GLU L H    1 
ATOM   6235 H HA   . GLU C 3 106 ? 2.191   11.375 20.936  1.00 15.28 ? 106 GLU L HA   1 
ATOM   6236 H HB2  . GLU C 3 106 ? -0.067  11.293 21.263  1.00 17.87 ? 106 GLU L HB2  1 
ATOM   6237 H HB3  . GLU C 3 106 ? 0.074   11.205 19.683  1.00 17.87 ? 106 GLU L HB3  1 
ATOM   6238 H HG2  . GLU C 3 106 ? -0.215  8.938  19.751  1.00 19.99 ? 106 GLU L HG2  1 
ATOM   6239 H HG3  . GLU C 3 106 ? -0.255  8.969  21.340  1.00 19.99 ? 106 GLU L HG3  1 
ATOM   6240 N N    . ILE C 3 107 ? 1.765   9.895  23.000  1.00 14.59 ? 107 ILE L N    1 
ATOM   6241 C CA   . ILE C 3 107 ? 1.879   9.003  24.154  1.00 17.48 ? 107 ILE L CA   1 
ATOM   6242 C C    . ILE C 3 107 ? 0.654   8.101  24.223  1.00 17.85 ? 107 ILE L C    1 
ATOM   6243 O O    . ILE C 3 107 ? -0.491  8.573  24.237  1.00 15.33 ? 107 ILE L O    1 
ATOM   6244 C CB   . ILE C 3 107 ? 2.051   9.803  25.460  1.00 20.69 ? 107 ILE L CB   1 
ATOM   6245 C CG1  . ILE C 3 107 ? 3.368   10.569 25.467  1.00 24.47 ? 107 ILE L CG1  1 
ATOM   6246 C CG2  . ILE C 3 107 ? 1.941   8.874  26.651  1.00 26.65 ? 107 ILE L CG2  1 
ATOM   6247 C CD1  . ILE C 3 107 ? 3.428   11.680 26.494  1.00 36.56 ? 107 ILE L CD1  1 
ATOM   6248 H H    . ILE C 3 107 ? 1.519   10.693 23.206  1.00 17.57 ? 107 ILE L H    1 
ATOM   6249 H HA   . ILE C 3 107 ? 2.662   8.443  24.033  1.00 21.04 ? 107 ILE L HA   1 
ATOM   6250 H HB   . ILE C 3 107 ? 1.340   10.461 25.517  1.00 24.89 ? 107 ILE L HB   1 
ATOM   6251 H HG12 . ILE C 3 107 ? 4.088   9.949  25.661  1.00 29.43 ? 107 ILE L HG12 1 
ATOM   6252 H HG13 . ILE C 3 107 ? 3.501   10.968 24.593  1.00 29.43 ? 107 ILE L HG13 1 
ATOM   6253 H HG21 . ILE C 3 107 ? 2.062   9.388  27.465  1.00 32.04 ? 107 ILE L HG21 1 
ATOM   6254 H HG22 . ILE C 3 107 ? 1.064   8.460  26.648  1.00 32.04 ? 107 ILE L HG22 1 
ATOM   6255 H HG23 . ILE C 3 107 ? 2.629   8.193  26.585  1.00 32.04 ? 107 ILE L HG23 1 
ATOM   6256 H HD11 . ILE C 3 107 ? 4.285   12.130 26.423  1.00 43.93 ? 107 ILE L HD11 1 
ATOM   6257 H HD12 . ILE C 3 107 ? 2.710   12.308 26.322  1.00 43.93 ? 107 ILE L HD12 1 
ATOM   6258 H HD13 . ILE C 3 107 ? 3.329   11.297 27.379  1.00 43.93 ? 107 ILE L HD13 1 
ATOM   6259 N N    . LYS C 3 108 ? 0.907   6.795  24.376  1.00 15.08 ? 108 LYS L N    1 
ATOM   6260 C CA   . LYS C 3 108 ? -0.161  5.833  24.559  1.00 19.40 ? 108 LYS L CA   1 
ATOM   6261 C C    . LYS C 3 108 ? -0.526  5.736  26.030  1.00 18.88 ? 108 LYS L C    1 
ATOM   6262 O O    . LYS C 3 108 ? 0.338   5.786  26.910  1.00 19.58 ? 108 LYS L O    1 
ATOM   6263 C CB   . LYS C 3 108 ? 0.260   4.467  24.037  1.00 23.92 ? 108 LYS L CB   1 
ATOM   6264 C CG   . LYS C 3 108 ? -0.704  3.355  24.423  1.00 32.25 ? 108 LYS L CG   1 
ATOM   6265 C CD   . LYS C 3 108 ? -1.824  3.263  23.439  1.00 26.88 ? 108 LYS L CD   1 
ATOM   6266 C CE   . LYS C 3 108 ? -2.316  1.800  23.194  1.00 32.50 ? 108 LYS L CE   1 
ATOM   6267 N NZ   . LYS C 3 108 ? -2.600  1.477  21.792  1.00 41.80 ? 108 LYS L NZ   1 
ATOM   6268 H H    . LYS C 3 108 ? 1.695   6.450  24.377  1.00 18.16 ? 108 LYS L H    1 
ATOM   6269 H HA   . LYS C 3 108 ? -0.945  6.117  24.063  1.00 23.34 ? 108 LYS L HA   1 
ATOM   6270 H HB2  . LYS C 3 108 ? 0.304   4.500  23.068  1.00 28.76 ? 108 LYS L HB2  1 
ATOM   6271 H HB3  . LYS C 3 108 ? 1.131   4.246  24.401  1.00 28.76 ? 108 LYS L HB3  1 
ATOM   6272 H HG2  . LYS C 3 108 ? -0.234  2.507  24.435  1.00 38.76 ? 108 LYS L HG2  1 
ATOM   6273 H HG3  . LYS C 3 108 ? -1.078  3.540  25.299  1.00 38.76 ? 108 LYS L HG3  1 
ATOM   6274 H HD2  . LYS C 3 108 ? -2.576  3.778  23.769  1.00 32.32 ? 108 LYS L HD2  1 
ATOM   6275 H HD3  . LYS C 3 108 ? -1.524  3.622  22.588  1.00 32.32 ? 108 LYS L HD3  1 
ATOM   6276 H HE2  . LYS C 3 108 ? -1.630  1.188  23.501  1.00 39.06 ? 108 LYS L HE2  1 
ATOM   6277 H HE3  . LYS C 3 108 ? -3.134  1.661  23.697  1.00 39.06 ? 108 LYS L HE3  1 
ATOM   6278 H HZ1  . LYS C 3 108 ? -2.884  0.636  21.725  1.00 50.23 ? 108 LYS L HZ1  1 
ATOM   6279 H HZ2  . LYS C 3 108 ? -3.230  2.020  21.476  1.00 50.23 ? 108 LYS L HZ2  1 
ATOM   6280 H HZ3  . LYS C 3 108 ? -1.863  1.573  21.303  1.00 50.23 ? 108 LYS L HZ3  1 
ATOM   6281 N N    . ARG C 3 109 ? -1.825  5.668  26.288  1.00 16.01 ? 109 ARG L N    1 
ATOM   6282 C CA   . ARG C 3 109 ? -2.313  5.406  27.641  1.00 17.37 ? 109 ARG L CA   1 
ATOM   6283 C C    . ARG C 3 109 ? -3.563  4.549  27.499  1.00 16.48 ? 109 ARG L C    1 
ATOM   6284 O O    . ARG C 3 109 ? -3.974  4.211  26.394  1.00 15.14 ? 109 ARG L O    1 
ATOM   6285 C CB   . ARG C 3 109 ? -2.563  6.717  28.391  1.00 14.28 ? 109 ARG L CB   1 
ATOM   6286 C CG   . ARG C 3 109 ? -3.565  7.614  27.691  1.00 15.43 ? 109 ARG L CG   1 
ATOM   6287 C CD   . ARG C 3 109 ? -4.415  8.422  28.671  1.00 16.09 ? 109 ARG L CD   1 
ATOM   6288 N NE   . ARG C 3 109 ? -5.303  7.547  29.412  1.00 16.30 ? 109 ARG L NE   1 
ATOM   6289 C CZ   . ARG C 3 109 ? -5.662  7.709  30.667  1.00 20.09 ? 109 ARG L CZ   1 
ATOM   6290 N NH1  . ARG C 3 109 ? -5.313  8.795  31.362  1.00 18.96 ? 109 ARG L NH1  1 
ATOM   6291 N NH2  . ARG C 3 109 ? -6.513  6.844  31.192  1.00 20.84 ? 109 ARG L NH2  1 
ATOM   6292 H H    . ARG C 3 109 ? -2.444  5.768  25.700  1.00 19.27 ? 109 ARG L H    1 
ATOM   6293 H HA   . ARG C 3 109 ? -1.659  4.909  28.157  1.00 20.91 ? 109 ARG L HA   1 
ATOM   6294 H HB2  . ARG C 3 109 ? -2.908  6.513  29.274  1.00 17.20 ? 109 ARG L HB2  1 
ATOM   6295 H HB3  . ARG C 3 109 ? -1.726  7.202  28.465  1.00 17.20 ? 109 ARG L HB3  1 
ATOM   6296 H HG2  . ARG C 3 109 ? -3.088  8.239  27.122  1.00 18.57 ? 109 ARG L HG2  1 
ATOM   6297 H HG3  . ARG C 3 109 ? -4.161  7.067  27.156  1.00 18.57 ? 109 ARG L HG3  1 
ATOM   6298 H HD2  . ARG C 3 109 ? -3.837  8.881  29.301  1.00 19.37 ? 109 ARG L HD2  1 
ATOM   6299 H HD3  . ARG C 3 109 ? -4.951  9.066  28.183  1.00 19.37 ? 109 ARG L HD3  1 
ATOM   6300 H HE   . ARG C 3 109 ? -5.622  6.865  28.996  1.00 19.62 ? 109 ARG L HE   1 
ATOM   6301 H HH11 . ARG C 3 109 ? -4.841  9.410  30.989  1.00 22.81 ? 109 ARG L HH11 1 
ATOM   6302 H HH12 . ARG C 3 109 ? -5.559  8.879  32.181  1.00 22.81 ? 109 ARG L HH12 1 
ATOM   6303 H HH21 . ARG C 3 109 ? -6.817  6.196  30.715  1.00 25.07 ? 109 ARG L HH21 1 
ATOM   6304 H HH22 . ARG C 3 109 ? -6.763  6.929  32.010  1.00 25.07 ? 109 ARG L HH22 1 
ATOM   6305 N N    . THR C 3 110 ? -4.152  4.173  28.623  1.00 16.94 ? 110 THR L N    1 
ATOM   6306 C CA   . THR C 3 110 ? -5.372  3.400  28.576  1.00 18.15 ? 110 THR L CA   1 
ATOM   6307 C C    . THR C 3 110 ? -6.551  4.211  28.037  1.00 17.90 ? 110 THR L C    1 
ATOM   6308 O O    . THR C 3 110 ? -6.586  5.447  28.070  1.00 14.78 ? 110 THR L O    1 
ATOM   6309 C CB   . THR C 3 110 ? -5.610  2.815  29.961  1.00 20.55 ? 110 THR L CB   1 
ATOM   6310 O OG1  . THR C 3 110 ? -5.975  3.889  30.851  1.00 19.70 ? 110 THR L OG1  1 
ATOM   6311 C CG2  . THR C 3 110 ? -4.443  2.021  30.455  1.00 19.70 ? 110 THR L CG2  1 
ATOM   6312 H H    . THR C 3 110 ? -3.866  4.352  29.414  1.00 20.39 ? 110 THR L H    1 
ATOM   6313 H HA   . THR C 3 110 ? -5.302  2.663  27.950  1.00 21.85 ? 110 THR L HA   1 
ATOM   6314 H HB   . THR C 3 110 ? -6.336  2.173  29.936  1.00 24.72 ? 110 THR L HB   1 
ATOM   6315 H HG1  . THR C 3 110 ? -5.899  3.640  31.649  1.00 23.70 ? 110 THR L HG1  1 
ATOM   6316 H HG21 . THR C 3 110 ? -4.738  1.377  31.118  1.00 23.70 ? 110 THR L HG21 1 
ATOM   6317 H HG22 . THR C 3 110 ? -4.029  1.547  29.717  1.00 23.70 ? 110 THR L HG22 1 
ATOM   6318 H HG23 . THR C 3 110 ? -3.788  2.611  30.859  1.00 23.70 ? 110 THR L HG23 1 
ATOM   6319 N N    . VAL C 3 111 ? -7.531  3.472  27.525  1.00 14.63 ? 111 VAL L N    1 
ATOM   6320 C CA   . VAL C 3 111 ? -8.785  4.094  27.147  1.00 14.94 ? 111 VAL L CA   1 
ATOM   6321 C C    . VAL C 3 111 ? -9.430  4.813  28.314  1.00 15.55 ? 111 VAL L C    1 
ATOM   6322 O O    . VAL C 3 111 ? -9.523  4.288  29.421  1.00 17.32 ? 111 VAL L O    1 
ATOM   6323 C CB   . VAL C 3 111 ? -9.737  3.049  26.543  1.00 17.04 ? 111 VAL L CB   1 
ATOM   6324 C CG1  . VAL C 3 111 ? -11.024 3.681  26.120  1.00 18.56 ? 111 VAL L CG1  1 
ATOM   6325 C CG2  . VAL C 3 111 ? -9.086  2.433  25.326  1.00 16.99 ? 111 VAL L CG2  1 
ATOM   6326 H H    . VAL C 3 111 ? -7.492  2.624  27.389  1.00 17.62 ? 111 VAL L H    1 
ATOM   6327 H HA   . VAL C 3 111 ? -8.587  4.767  26.476  1.00 17.99 ? 111 VAL L HA   1 
ATOM   6328 H HB   . VAL C 3 111 ? -9.925  2.373  27.212  1.00 20.50 ? 111 VAL L HB   1 
ATOM   6329 H HG11 . VAL C 3 111 ? -11.601 3.000  25.741  1.00 22.34 ? 111 VAL L HG11 1 
ATOM   6330 H HG12 . VAL C 3 111 ? -11.449 4.081  26.894  1.00 22.34 ? 111 VAL L HG12 1 
ATOM   6331 H HG13 . VAL C 3 111 ? -10.838 4.363  25.456  1.00 22.34 ? 111 VAL L HG13 1 
ATOM   6332 H HG21 . VAL C 3 111 ? -9.768  2.006  24.785  1.00 20.45 ? 111 VAL L HG21 1 
ATOM   6333 H HG22 . VAL C 3 111 ? -8.648  3.131  24.815  1.00 20.45 ? 111 VAL L HG22 1 
ATOM   6334 H HG23 . VAL C 3 111 ? -8.434  1.776  25.616  1.00 20.45 ? 111 VAL L HG23 1 
ATOM   6335 N N    . ALA C 3 112 ? -9.927  6.005  28.032  1.00 15.32 ? 112 ALA L N    1 
ATOM   6336 C CA   . ALA C 3 112 ? -10.672 6.805  28.996  1.00 17.40 ? 112 ALA L CA   1 
ATOM   6337 C C    . ALA C 3 112 ? -11.843 7.425  28.252  1.00 21.28 ? 112 ALA L C    1 
ATOM   6338 O O    . ALA C 3 112 ? -11.644 8.178  27.297  1.00 19.21 ? 112 ALA L O    1 
ATOM   6339 C CB   . ALA C 3 112 ? -9.782  7.882  29.617  1.00 19.61 ? 112 ALA L CB   1 
ATOM   6340 H H    . ALA C 3 112 ? -9.845  6.387  27.265  1.00 18.45 ? 112 ALA L H    1 
ATOM   6341 H HA   . ALA C 3 112 ? -11.011 6.250  29.716  1.00 20.94 ? 112 ALA L HA   1 
ATOM   6342 H HB1  . ALA C 3 112 ? -10.297 8.379  30.271  1.00 23.60 ? 112 ALA L HB1  1 
ATOM   6343 H HB2  . ALA C 3 112 ? -9.024  7.456  30.047  1.00 23.60 ? 112 ALA L HB2  1 
ATOM   6344 H HB3  . ALA C 3 112 ? -9.473  8.478  28.917  1.00 23.60 ? 112 ALA L HB3  1 
ATOM   6345 N N    . ALA C 3 113 ? -13.065 7.113  28.673  1.00 18.96 ? 113 ALA L N    1 
ATOM   6346 C CA   . ALA C 3 113 ? -14.211 7.705  28.008  1.00 21.59 ? 113 ALA L CA   1 
ATOM   6347 C C    . ALA C 3 113 ? -14.348 9.174  28.410  1.00 16.27 ? 113 ALA L C    1 
ATOM   6348 O O    . ALA C 3 113 ? -13.982 9.551  29.521  1.00 19.63 ? 113 ALA L O    1 
ATOM   6349 C CB   . ALA C 3 113 ? -15.505 6.974  28.363  1.00 21.16 ? 113 ALA L CB   1 
ATOM   6350 H H    . ALA C 3 113 ? -13.249 6.577  29.320  1.00 22.81 ? 113 ALA L H    1 
ATOM   6351 H HA   . ALA C 3 113 ? -14.082 7.641  27.049  1.00 25.97 ? 113 ALA L HA   1 
ATOM   6352 H HB1  . ALA C 3 113 ? -16.240 7.377  27.876  1.00 25.45 ? 113 ALA L HB1  1 
ATOM   6353 H HB2  . ALA C 3 113 ? -15.418 6.040  28.116  1.00 25.45 ? 113 ALA L HB2  1 
ATOM   6354 H HB3  . ALA C 3 113 ? -15.660 7.050  29.318  1.00 25.45 ? 113 ALA L HB3  1 
ATOM   6355 N N    . PRO C 3 114 ? -14.831 10.020 27.510  1.00 18.94 ? 114 PRO L N    1 
ATOM   6356 C CA   . PRO C 3 114 ? -15.029 11.428 27.871  1.00 19.08 ? 114 PRO L CA   1 
ATOM   6357 C C    . PRO C 3 114 ? -16.140 11.596 28.886  1.00 21.66 ? 114 PRO L C    1 
ATOM   6358 O O    . PRO C 3 114 ? -17.122 10.855 28.896  1.00 22.01 ? 114 PRO L O    1 
ATOM   6359 C CB   . PRO C 3 114 ? -15.425 12.076 26.547  1.00 22.37 ? 114 PRO L CB   1 
ATOM   6360 C CG   . PRO C 3 114 ? -16.103 10.952 25.783  1.00 23.73 ? 114 PRO L CG   1 
ATOM   6361 C CD   . PRO C 3 114 ? -15.308 9.745  26.147  1.00 20.54 ? 114 PRO L CD   1 
ATOM   6362 H HA   . PRO C 3 114 ? -14.205 11.811 28.209  1.00 22.96 ? 114 PRO L HA   1 
ATOM   6363 H HB2  . PRO C 3 114 ? -16.037 12.813 26.705  1.00 26.91 ? 114 PRO L HB2  1 
ATOM   6364 H HB3  . PRO C 3 114 ? -14.637 12.393 26.080  1.00 26.91 ? 114 PRO L HB3  1 
ATOM   6365 H HG2  . PRO C 3 114 ? -17.026 10.863 26.067  1.00 28.53 ? 114 PRO L HG2  1 
ATOM   6366 H HG3  . PRO C 3 114 ? -16.064 11.124 24.830  1.00 28.53 ? 114 PRO L HG3  1 
ATOM   6367 H HD2  . PRO C 3 114 ? -15.866 8.952  26.134  1.00 24.71 ? 114 PRO L HD2  1 
ATOM   6368 H HD3  . PRO C 3 114 ? -14.560 9.634  25.540  1.00 24.71 ? 114 PRO L HD3  1 
ATOM   6369 N N    . SER C 3 115 ? -15.970 12.577 29.754  1.00 20.59 ? 115 SER L N    1 
ATOM   6370 C CA   . SER C 3 115 ? -17.094 13.182 30.458  1.00 19.91 ? 115 SER L CA   1 
ATOM   6371 C C    . SER C 3 115 ? -17.683 14.234 29.540  1.00 23.40 ? 115 SER L C    1 
ATOM   6372 O O    . SER C 3 115 ? -16.948 15.070 29.010  1.00 19.07 ? 115 SER L O    1 
ATOM   6373 C CB   . SER C 3 115 ? -16.621 13.805 31.769  1.00 22.65 ? 115 SER L CB   1 
ATOM   6374 O OG   . SER C 3 115 ? -16.145 12.810 32.640  1.00 35.06 ? 115 SER L OG   1 
ATOM   6375 H H    . SER C 3 115 ? -15.207 12.916 29.959  1.00 24.77 ? 115 SER L H    1 
ATOM   6376 H HA   . SER C 3 115 ? -17.771 12.524 30.682  1.00 23.95 ? 115 SER L HA   1 
ATOM   6377 H HB2  . SER C 3 115 ? -15.906 14.433 31.583  1.00 27.24 ? 115 SER L HB2  1 
ATOM   6378 H HB3  . SER C 3 115 ? -17.365 14.265 32.189  1.00 27.24 ? 115 SER L HB3  1 
ATOM   6379 H HG   . SER C 3 115 ? -15.841 13.161 33.340  1.00 42.13 ? 115 SER L HG   1 
ATOM   6380 N N    . VAL C 3 116 ? -19.002 14.211 29.361  1.00 20.96 ? 116 VAL L N    1 
ATOM   6381 C CA   . VAL C 3 116 ? -19.667 15.074 28.397  1.00 19.52 ? 116 VAL L CA   1 
ATOM   6382 C C    . VAL C 3 116 ? -20.563 16.063 29.127  1.00 21.86 ? 116 VAL L C    1 
ATOM   6383 O O    . VAL C 3 116 ? -21.239 15.710 30.106  1.00 20.02 ? 116 VAL L O    1 
ATOM   6384 C CB   . VAL C 3 116 ? -20.454 14.246 27.371  1.00 20.78 ? 116 VAL L CB   1 
ATOM   6385 C CG1  . VAL C 3 116 ? -20.990 15.115 26.285  1.00 22.34 ? 116 VAL L CG1  1 
ATOM   6386 C CG2  . VAL C 3 116 ? -19.570 13.145 26.803  1.00 23.92 ? 116 VAL L CG2  1 
ATOM   6387 H H    . VAL C 3 116 ? -19.537 13.696 29.795  1.00 25.21 ? 116 VAL L H    1 
ATOM   6388 H HA   . VAL C 3 116 ? -19.003 15.598 27.922  1.00 23.49 ? 116 VAL L HA   1 
ATOM   6389 H HB   . VAL C 3 116 ? -21.213 13.831 27.811  1.00 25.00 ? 116 VAL L HB   1 
ATOM   6390 H HG11 . VAL C 3 116 ? -21.351 14.555 25.580  1.00 26.87 ? 116 VAL L HG11 1 
ATOM   6391 H HG12 . VAL C 3 116 ? -21.690 15.680 26.649  1.00 26.87 ? 116 VAL L HG12 1 
ATOM   6392 H HG13 . VAL C 3 116 ? -20.271 15.664 25.936  1.00 26.87 ? 116 VAL L HG13 1 
ATOM   6393 H HG21 . VAL C 3 116 ? -20.054 12.682 26.101  1.00 28.77 ? 116 VAL L HG21 1 
ATOM   6394 H HG22 . VAL C 3 116 ? -18.763 13.544 26.440  1.00 28.77 ? 116 VAL L HG22 1 
ATOM   6395 H HG23 . VAL C 3 116 ? -19.342 12.525 27.513  1.00 28.77 ? 116 VAL L HG23 1 
ATOM   6396 N N    . PHE C 3 117 ? -20.509 17.316 28.661  1.00 18.94 ? 117 PHE L N    1 
ATOM   6397 C CA   . PHE C 3 117 ? -21.246 18.434 29.224  1.00 21.09 ? 117 PHE L CA   1 
ATOM   6398 C C    . PHE C 3 117 ? -21.814 19.276 28.085  1.00 21.22 ? 117 PHE L C    1 
ATOM   6399 O O    . PHE C 3 117 ? -21.146 19.517 27.069  1.00 21.60 ? 117 PHE L O    1 
ATOM   6400 C CB   . PHE C 3 117 ? -20.366 19.289 30.125  1.00 21.05 ? 117 PHE L CB   1 
ATOM   6401 C CG   . PHE C 3 117 ? -19.705 18.531 31.235  1.00 20.13 ? 117 PHE L CG   1 
ATOM   6402 C CD1  . PHE C 3 117 ? -18.475 17.932 31.053  1.00 20.00 ? 117 PHE L CD1  1 
ATOM   6403 C CD2  . PHE C 3 117 ? -20.281 18.477 32.487  1.00 21.54 ? 117 PHE L CD2  1 
ATOM   6404 C CE1  . PHE C 3 117 ? -17.861 17.278 32.070  1.00 21.17 ? 117 PHE L CE1  1 
ATOM   6405 C CE2  . PHE C 3 117 ? -19.653 17.812 33.532  1.00 22.34 ? 117 PHE L CE2  1 
ATOM   6406 C CZ   . PHE C 3 117 ? -18.442 17.197 33.311  1.00 20.96 ? 117 PHE L CZ   1 
ATOM   6407 H H    . PHE C 3 117 ? -20.028 17.547 27.987  1.00 22.79 ? 117 PHE L H    1 
ATOM   6408 H HA   . PHE C 3 117 ? -21.986 18.105 29.759  1.00 25.37 ? 117 PHE L HA   1 
ATOM   6409 H HB2  . PHE C 3 117 ? -19.667 19.690 29.586  1.00 25.32 ? 117 PHE L HB2  1 
ATOM   6410 H HB3  . PHE C 3 117 ? -20.914 19.982 30.527  1.00 25.32 ? 117 PHE L HB3  1 
ATOM   6411 H HD1  . PHE C 3 117 ? -18.062 17.978 30.221  1.00 24.06 ? 117 PHE L HD1  1 
ATOM   6412 H HD2  . PHE C 3 117 ? -21.101 18.891 32.633  1.00 25.91 ? 117 PHE L HD2  1 
ATOM   6413 H HE1  . PHE C 3 117 ? -17.033 16.879 31.925  1.00 25.47 ? 117 PHE L HE1  1 
ATOM   6414 H HE2  . PHE C 3 117 ? -20.046 17.783 34.374  1.00 26.87 ? 117 PHE L HE2  1 
ATOM   6415 H HZ   . PHE C 3 117 ? -18.021 16.730 33.996  1.00 25.21 ? 117 PHE L HZ   1 
ATOM   6416 N N    . ILE C 3 118 ? -23.060 19.722 28.231  1.00 23.58 ? 118 ILE L N    1 
ATOM   6417 C CA   . ILE C 3 118 ? -23.674 20.604 27.241  1.00 20.92 ? 118 ILE L CA   1 
ATOM   6418 C C    . ILE C 3 118 ? -23.959 21.965 27.887  1.00 20.99 ? 118 ILE L C    1 
ATOM   6419 O O    . ILE C 3 118 ? -24.382 22.018 29.050  1.00 21.42 ? 118 ILE L O    1 
ATOM   6420 C CB   . ILE C 3 118 ? -24.974 20.012 26.655  1.00 25.25 ? 118 ILE L CB   1 
ATOM   6421 C CG1  . ILE C 3 118 ? -25.441 20.826 25.449  1.00 24.27 ? 118 ILE L CG1  1 
ATOM   6422 C CG2  . ILE C 3 118 ? -26.086 19.962 27.693  1.00 31.22 ? 118 ILE L CG2  1 
ATOM   6423 C CD1  . ILE C 3 118 ? -25.978 20.030 24.326  1.00 28.13 ? 118 ILE L CD1  1 
ATOM   6424 H H    . ILE C 3 118 ? -23.569 19.527 28.895  1.00 28.35 ? 118 ILE L H    1 
ATOM   6425 H HA   . ILE C 3 118 ? -23.042 20.732 26.516  1.00 25.17 ? 118 ILE L HA   1 
ATOM   6426 H HB   . ILE C 3 118 ? -24.771 19.105 26.376  1.00 30.36 ? 118 ILE L HB   1 
ATOM   6427 H HG12 . ILE C 3 118 ? -26.143 21.429 25.739  1.00 29.19 ? 118 ILE L HG12 1 
ATOM   6428 H HG13 . ILE C 3 118 ? -24.686 21.333 25.111  1.00 29.19 ? 118 ILE L HG13 1 
ATOM   6429 H HG21 . ILE C 3 118 ? -26.810 19.411 27.354  1.00 37.52 ? 118 ILE L HG21 1 
ATOM   6430 H HG22 . ILE C 3 118 ? -25.736 19.580 28.513  1.00 37.52 ? 118 ILE L HG22 1 
ATOM   6431 H HG23 . ILE C 3 118 ? -26.405 20.863 27.858  1.00 37.52 ? 118 ILE L HG23 1 
ATOM   6432 H HD11 . ILE C 3 118 ? -26.247 20.630 23.613  1.00 33.81 ? 118 ILE L HD11 1 
ATOM   6433 H HD12 . ILE C 3 118 ? -25.288 19.427 24.007  1.00 33.81 ? 118 ILE L HD12 1 
ATOM   6434 H HD13 . ILE C 3 118 ? -26.743 19.521 24.637  1.00 33.81 ? 118 ILE L HD13 1 
ATOM   6435 N N    . PHE C 3 119 ? -23.771 23.056 27.133  1.00 21.88 ? 119 PHE L N    1 
ATOM   6436 C CA   . PHE C 3 119 ? -23.987 24.420 27.632  1.00 21.69 ? 119 PHE L CA   1 
ATOM   6437 C C    . PHE C 3 119 ? -24.949 25.171 26.722  1.00 21.09 ? 119 PHE L C    1 
ATOM   6438 O O    . PHE C 3 119 ? -24.640 25.385 25.529  1.00 21.63 ? 119 PHE L O    1 
ATOM   6439 C CB   . PHE C 3 119 ? -22.700 25.244 27.763  1.00 19.38 ? 119 PHE L CB   1 
ATOM   6440 C CG   . PHE C 3 119 ? -21.699 24.648 28.716  1.00 22.13 ? 119 PHE L CG   1 
ATOM   6441 C CD1  . PHE C 3 119 ? -21.794 24.870 30.086  1.00 23.21 ? 119 PHE L CD1  1 
ATOM   6442 C CD2  . PHE C 3 119 ? -20.651 23.879 28.241  1.00 20.26 ? 119 PHE L CD2  1 
ATOM   6443 C CE1  . PHE C 3 119 ? -20.869 24.306 30.965  1.00 19.75 ? 119 PHE L CE1  1 
ATOM   6444 C CE2  . PHE C 3 119 ? -19.747 23.301 29.101  1.00 18.30 ? 119 PHE L CE2  1 
ATOM   6445 C CZ   . PHE C 3 119 ? -19.856 23.526 30.477  1.00 20.35 ? 119 PHE L CZ   1 
ATOM   6446 H H    . PHE C 3 119 ? -23.513 23.031 26.313  1.00 26.31 ? 119 PHE L H    1 
ATOM   6447 H HA   . PHE C 3 119 ? -24.381 24.308 28.512  1.00 26.09 ? 119 PHE L HA   1 
ATOM   6448 H HB2  . PHE C 3 119 ? -22.280 25.308 26.891  1.00 23.31 ? 119 PHE L HB2  1 
ATOM   6449 H HB3  . PHE C 3 119 ? -22.928 26.130 28.087  1.00 23.31 ? 119 PHE L HB3  1 
ATOM   6450 H HD1  . PHE C 3 119 ? -22.481 25.400 30.419  1.00 27.91 ? 119 PHE L HD1  1 
ATOM   6451 H HD2  . PHE C 3 119 ? -20.557 23.751 27.325  1.00 24.37 ? 119 PHE L HD2  1 
ATOM   6452 H HE1  . PHE C 3 119 ? -20.941 24.460 31.879  1.00 23.76 ? 119 PHE L HE1  1 
ATOM   6453 H HE2  . PHE C 3 119 ? -19.065 22.762 28.769  1.00 22.02 ? 119 PHE L HE2  1 
ATOM   6454 H HZ   . PHE C 3 119 ? -19.241 23.145 31.061  1.00 24.48 ? 119 PHE L HZ   1 
ATOM   6455 N N    . PRO C 3 120 ? -26.064 25.669 27.244  1.00 24.62 ? 120 PRO L N    1 
ATOM   6456 C CA   . PRO C 3 120 ? -26.933 26.535 26.441  1.00 22.48 ? 120 PRO L CA   1 
ATOM   6457 C C    . PRO C 3 120 ? -26.270 27.873 26.170  1.00 22.27 ? 120 PRO L C    1 
ATOM   6458 O O    . PRO C 3 120 ? -25.307 28.242 26.859  1.00 26.49 ? 120 PRO L O    1 
ATOM   6459 C CB   . PRO C 3 120 ? -28.171 26.706 27.338  1.00 22.84 ? 120 PRO L CB   1 
ATOM   6460 C CG   . PRO C 3 120 ? -28.169 25.548 28.253  1.00 28.95 ? 120 PRO L CG   1 
ATOM   6461 C CD   . PRO C 3 120 ? -26.698 25.288 28.527  1.00 24.92 ? 120 PRO L CD   1 
ATOM   6462 H HA   . PRO C 3 120 ? -27.177 26.110 25.604  1.00 27.04 ? 120 PRO L HA   1 
ATOM   6463 H HB2  . PRO C 3 120 ? -28.102 27.537 27.834  1.00 27.46 ? 120 PRO L HB2  1 
ATOM   6464 H HB3  . PRO C 3 120 ? -28.972 26.712 26.791  1.00 27.46 ? 120 PRO L HB3  1 
ATOM   6465 H HG2  . PRO C 3 120 ? -28.644 25.769 29.070  1.00 34.80 ? 120 PRO L HG2  1 
ATOM   6466 H HG3  . PRO C 3 120 ? -28.585 24.784 27.823  1.00 34.80 ? 120 PRO L HG3  1 
ATOM   6467 H HD2  . PRO C 3 120 ? -26.376 25.843 29.254  1.00 29.97 ? 120 PRO L HD2  1 
ATOM   6468 H HD3  . PRO C 3 120 ? -26.542 24.352 28.729  1.00 29.97 ? 120 PRO L HD3  1 
ATOM   6469 N N    . PRO C 3 121 ? -26.760 28.644 25.196  1.00 25.46 ? 121 PRO L N    1 
ATOM   6470 C CA   . PRO C 3 121 ? -26.294 30.018 25.047  1.00 24.04 ? 121 PRO L CA   1 
ATOM   6471 C C    . PRO C 3 121 ? -26.661 30.770 26.312  1.00 24.83 ? 121 PRO L C    1 
ATOM   6472 O O    . PRO C 3 121 ? -27.692 30.497 26.941  1.00 26.06 ? 121 PRO L O    1 
ATOM   6473 C CB   . PRO C 3 121 ? -27.082 30.552 23.844  1.00 29.05 ? 121 PRO L CB   1 
ATOM   6474 C CG   . PRO C 3 121 ? -27.998 29.478 23.412  1.00 30.81 ? 121 PRO L CG   1 
ATOM   6475 C CD   . PRO C 3 121 ? -27.821 28.286 24.248  1.00 26.62 ? 121 PRO L CD   1 
ATOM   6476 H HA   . PRO C 3 121 ? -25.347 30.074 24.846  1.00 28.91 ? 121 PRO L HA   1 
ATOM   6477 H HB2  . PRO C 3 121 ? -27.584 31.338 24.111  1.00 34.92 ? 121 PRO L HB2  1 
ATOM   6478 H HB3  . PRO C 3 121 ? -26.465 30.779 23.131  1.00 34.92 ? 121 PRO L HB3  1 
ATOM   6479 H HG2  . PRO C 3 121 ? -28.910 29.800 23.491  1.00 37.03 ? 121 PRO L HG2  1 
ATOM   6480 H HG3  . PRO C 3 121 ? -27.803 29.261 22.487  1.00 37.03 ? 121 PRO L HG3  1 
ATOM   6481 H HD2  . PRO C 3 121 ? -28.642 28.078 24.721  1.00 32.01 ? 121 PRO L HD2  1 
ATOM   6482 H HD3  . PRO C 3 121 ? -27.549 27.528 23.706  1.00 32.01 ? 121 PRO L HD3  1 
ATOM   6483 N N    . SER C 3 122 ? -25.830 31.733 26.666  1.00 20.47 ? 122 SER L N    1 
ATOM   6484 C CA   . SER C 3 122 ? -26.164 32.639 27.751  1.00 24.10 ? 122 SER L CA   1 
ATOM   6485 C C    . SER C 3 122 ? -27.257 33.607 27.303  1.00 22.80 ? 122 SER L C    1 
ATOM   6486 O O    . SER C 3 122 ? -27.379 33.926 26.122  1.00 24.63 ? 122 SER L O    1 
ATOM   6487 C CB   . SER C 3 122 ? -24.936 33.451 28.178  1.00 22.40 ? 122 SER L CB   1 
ATOM   6488 O OG   . SER C 3 122 ? -24.486 34.305 27.133  1.00 25.52 ? 122 SER L OG   1 
ATOM   6489 H H    . SER C 3 122 ? -25.069 31.885 26.297  1.00 24.63 ? 122 SER L H    1 
ATOM   6490 H HA   . SER C 3 122 ? -26.473 32.124 28.512  1.00 28.98 ? 122 SER L HA   1 
ATOM   6491 H HB2  . SER C 3 122 ? -25.172 33.993 28.947  1.00 26.94 ? 122 SER L HB2  1 
ATOM   6492 H HB3  . SER C 3 122 ? -24.221 32.838 28.411  1.00 26.94 ? 122 SER L HB3  1 
ATOM   6493 H HG   . SER C 3 122 ? -24.070 33.859 26.556  1.00 30.69 ? 122 SER L HG   1 
ATOM   6494 N N    . ASP C 3 123 ? -28.011 34.141 28.268  1.00 28.40 ? 123 ASP L N    1 
ATOM   6495 C CA   . ASP C 3 123 ? -28.966 35.193 27.947  1.00 29.46 ? 123 ASP L CA   1 
ATOM   6496 C C    . ASP C 3 123 ? -28.250 36.429 27.447  1.00 30.14 ? 123 ASP L C    1 
ATOM   6497 O O    . ASP C 3 123 ? -28.751 37.121 26.553  1.00 31.24 ? 123 ASP L O    1 
ATOM   6498 C CB   . ASP C 3 123 ? -29.802 35.525 29.181  1.00 31.70 ? 123 ASP L CB   1 
ATOM   6499 C CG   . ASP C 3 123 ? -30.790 34.435 29.514  1.00 34.63 ? 123 ASP L CG   1 
ATOM   6500 O OD1  . ASP C 3 123 ? -31.198 33.717 28.578  1.00 42.42 ? 123 ASP L OD1  1 
ATOM   6501 O OD2  . ASP C 3 123 ? -31.150 34.300 30.710  1.00 35.07 ? 123 ASP L OD2  1 
ATOM   6502 H H    . ASP C 3 123 ? -27.988 33.914 29.097  1.00 34.14 ? 123 ASP L H    1 
ATOM   6503 H HA   . ASP C 3 123 ? -29.564 34.883 27.250  1.00 35.41 ? 123 ASP L HA   1 
ATOM   6504 H HB2  . ASP C 3 123 ? -29.212 35.640 29.942  1.00 38.10 ? 123 ASP L HB2  1 
ATOM   6505 H HB3  . ASP C 3 123 ? -30.298 36.342 29.018  1.00 38.10 ? 123 ASP L HB3  1 
ATOM   6506 N N    . GLU C 3 124 ? -27.072 36.729 28.010  1.00 24.16 ? 124 GLU L N    1 
ATOM   6507 C CA   . GLU C 3 124 ? -26.338 37.906 27.557  1.00 26.65 ? 124 GLU L CA   1 
ATOM   6508 C C    . GLU C 3 124 ? -26.038 37.811 26.059  1.00 30.50 ? 124 GLU L C    1 
ATOM   6509 O O    . GLU C 3 124 ? -26.183 38.796 25.323  1.00 33.18 ? 124 GLU L O    1 
ATOM   6510 C CB   . GLU C 3 124 ? -25.040 38.071 28.364  1.00 30.86 ? 124 GLU L CB   1 
ATOM   6511 C CG   . GLU C 3 124 ? -24.085 39.174 27.860  1.00 31.23 ? 124 GLU L CG   1 
ATOM   6512 C CD   . GLU C 3 124 ? -22.964 39.489 28.843  1.00 29.04 ? 124 GLU L CD   1 
ATOM   6513 H H    . GLU C 3 124 ? -26.691 36.279 28.636  1.00 29.05 ? 124 GLU L H    1 
ATOM   6514 H HA   . GLU C 3 124 ? -26.879 38.696 27.711  1.00 32.05 ? 124 GLU L HA   1 
ATOM   6515 H HB2  . GLU C 3 124 ? -25.275 38.289 29.280  1.00 37.09 ? 124 GLU L HB2  1 
ATOM   6516 H HB3  . GLU C 3 124 ? -24.554 37.233 28.337  1.00 37.09 ? 124 GLU L HB3  1 
ATOM   6517 H HG2  . GLU C 3 124 ? -23.679 38.884 27.028  1.00 37.53 ? 124 GLU L HG2  1 
ATOM   6518 H HG3  . GLU C 3 124 ? -24.592 39.988 27.715  1.00 37.53 ? 124 GLU L HG3  1 
ATOM   6519 N N    . GLN C 3 125 ? -25.632 36.625 25.584  1.00 29.09 ? 125 GLN L N    1 
ATOM   6520 C CA   . GLN C 3 125 ? -25.302 36.459 24.168  1.00 28.17 ? 125 GLN L CA   1 
ATOM   6521 C C    . GLN C 3 125 ? -26.539 36.554 23.294  1.00 30.70 ? 125 GLN L C    1 
ATOM   6522 O O    . GLN C 3 125 ? -26.510 37.161 22.221  1.00 31.56 ? 125 GLN L O    1 
ATOM   6523 C CB   . GLN C 3 125 ? -24.612 35.110 23.926  1.00 24.29 ? 125 GLN L CB   1 
ATOM   6524 C CG   . GLN C 3 125 ? -24.060 35.004 22.494  1.00 23.14 ? 125 GLN L CG   1 
ATOM   6525 C CD   . GLN C 3 125 ? -23.588 33.608 22.084  1.00 22.45 ? 125 GLN L CD   1 
ATOM   6526 O OE1  . GLN C 3 125 ? -23.894 32.593 22.704  1.00 23.29 ? 125 GLN L OE1  1 
ATOM   6527 N NE2  . GLN C 3 125 ? -22.891 33.563 20.970  1.00 25.99 ? 125 GLN L NE2  1 
ATOM   6528 H H    . GLN C 3 125 ? -25.540 35.912 26.057  1.00 34.96 ? 125 GLN L H    1 
ATOM   6529 H HA   . GLN C 3 125 ? -24.688 37.169 23.922  1.00 33.86 ? 125 GLN L HA   1 
ATOM   6530 H HB2  . GLN C 3 125 ? -23.872 35.014 24.546  1.00 29.21 ? 125 GLN L HB2  1 
ATOM   6531 H HB3  . GLN C 3 125 ? -25.252 34.394 24.060  1.00 29.21 ? 125 GLN L HB3  1 
ATOM   6532 H HG2  . GLN C 3 125 ? -24.759 35.267 21.875  1.00 27.83 ? 125 GLN L HG2  1 
ATOM   6533 H HG3  . GLN C 3 125 ? -23.301 35.603 22.412  1.00 27.83 ? 125 GLN L HG3  1 
ATOM   6534 H HE21 . GLN C 3 125 ? -22.733 34.286 20.532  1.00 31.25 ? 125 GLN L HE21 1 
ATOM   6535 H HE22 . GLN C 3 125 ? -22.593 32.810 20.680  1.00 31.25 ? 125 GLN L HE22 1 
ATOM   6536 N N    . LEU C 3 126 ? -27.630 35.947 23.726  1.00 29.21 ? 126 LEU L N    1 
ATOM   6537 C CA   . LEU C 3 126 ? -28.845 35.965 22.928  1.00 33.63 ? 126 LEU L CA   1 
ATOM   6538 C C    . LEU C 3 126 ? -29.313 37.388 22.683  1.00 36.32 ? 126 LEU L C    1 
ATOM   6539 O O    . LEU C 3 126 ? -29.766 37.721 21.585  1.00 38.79 ? 126 LEU L O    1 
ATOM   6540 C CB   . LEU C 3 126 ? -29.900 35.148 23.650  1.00 31.69 ? 126 LEU L CB   1 
ATOM   6541 C CG   . LEU C 3 126 ? -29.795 33.646 23.392  1.00 33.13 ? 126 LEU L CG   1 
ATOM   6542 C CD1  . LEU C 3 126 ? -30.866 32.913 24.157  1.00 32.84 ? 126 LEU L CD1  1 
ATOM   6543 C CD2  . LEU C 3 126 ? -29.871 33.356 21.886  1.00 35.08 ? 126 LEU L CD2  1 
ATOM   6544 H H    . LEU C 3 126 ? -27.696 35.521 24.471  1.00 35.11 ? 126 LEU L H    1 
ATOM   6545 H HA   . LEU C 3 126 ? -28.687 35.565 22.058  1.00 40.41 ? 126 LEU L HA   1 
ATOM   6546 H HB2  . LEU C 3 126 ? -29.807 35.292 24.605  1.00 38.08 ? 126 LEU L HB2  1 
ATOM   6547 H HB3  . LEU C 3 126 ? -30.777 35.440 23.354  1.00 38.08 ? 126 LEU L HB3  1 
ATOM   6548 H HG   . LEU C 3 126 ? -28.937 33.318 23.704  1.00 39.82 ? 126 LEU L HG   1 
ATOM   6549 H HD11 . LEU C 3 126 ? -30.674 31.962 24.137  1.00 39.46 ? 126 LEU L HD11 1 
ATOM   6550 H HD12 . LEU C 3 126 ? -30.873 33.230 25.073  1.00 39.46 ? 126 LEU L HD12 1 
ATOM   6551 H HD13 . LEU C 3 126 ? -31.725 33.085 23.741  1.00 39.46 ? 126 LEU L HD13 1 
ATOM   6552 H HD21 . LEU C 3 126 ? -30.265 32.479 21.753  1.00 42.15 ? 126 LEU L HD21 1 
ATOM   6553 H HD22 . LEU C 3 126 ? -30.420 34.033 21.461  1.00 42.15 ? 126 LEU L HD22 1 
ATOM   6554 H HD23 . LEU C 3 126 ? -28.975 33.375 21.515  1.00 42.15 ? 126 LEU L HD23 1 
ATOM   6555 N N    . LYS C 3 127 ? -29.147 38.257 23.680  1.00 37.49 ? 127 LYS L N    1 
ATOM   6556 C CA   . LYS C 3 127 ? -29.479 39.660 23.509  1.00 40.22 ? 127 LYS L CA   1 
ATOM   6557 C C    . LYS C 3 127 ? -28.730 40.266 22.332  1.00 43.72 ? 127 LYS L C    1 
ATOM   6558 O O    . LYS C 3 127 ? -29.229 41.205 21.705  1.00 48.57 ? 127 LYS L O    1 
ATOM   6559 C CB   . LYS C 3 127 ? -29.181 40.404 24.813  1.00 43.85 ? 127 LYS L CB   1 
ATOM   6560 C CG   . LYS C 3 127 ? -28.853 41.880 24.648  1.00 59.75 ? 127 LYS L CG   1 
ATOM   6561 C CD   . LYS C 3 127 ? -29.358 42.673 25.841  1.00 54.25 ? 127 LYS L CD   1 
ATOM   6562 C CE   . LYS C 3 127 ? -29.317 41.831 27.120  1.00 47.89 ? 127 LYS L CE   1 
ATOM   6563 N NZ   . LYS C 3 127 ? -29.972 42.535 28.261  1.00 50.60 ? 127 LYS L NZ   1 
ATOM   6564 H H    . LYS C 3 127 ? -28.845 38.056 24.460  1.00 45.05 ? 127 LYS L H    1 
ATOM   6565 N N    . SER C 3 128 ? -27.545 39.748 22.011  1.00 39.72 ? 128 SER L N    1 
ATOM   6566 C CA   . SER C 3 128 ? -26.777 40.218 20.865  1.00 36.69 ? 128 SER L CA   1 
ATOM   6567 C C    . SER C 3 128 ? -27.219 39.610 19.540  1.00 38.05 ? 128 SER L C    1 
ATOM   6568 O O    . SER C 3 128 ? -26.737 40.052 18.489  1.00 42.59 ? 128 SER L O    1 
ATOM   6569 C CB   . SER C 3 128 ? -25.301 39.894 21.060  1.00 39.34 ? 128 SER L CB   1 
ATOM   6570 O OG   . SER C 3 128 ? -25.022 38.558 20.631  1.00 44.35 ? 128 SER L OG   1 
ATOM   6571 H H    . SER C 3 128 ? -27.160 39.115 22.448  1.00 47.73 ? 128 SER L H    1 
ATOM   6572 H HA   . SER C 3 128 ? -26.892 41.179 20.812  1.00 44.08 ? 128 SER L HA   1 
ATOM   6573 H HB2  . SER C 3 128 ? -24.769 40.513 20.536  1.00 47.27 ? 128 SER L HB2  1 
ATOM   6574 H HB3  . SER C 3 128 ? -25.078 39.978 22.000  1.00 47.27 ? 128 SER L HB3  1 
ATOM   6575 H HG   . SER C 3 128 ? -25.565 38.024 20.984  1.00 53.28 ? 128 SER L HG   1 
ATOM   6576 N N    . GLY C 3 129 ? -28.089 38.598 19.550  1.00 38.68 ? 129 GLY L N    1 
ATOM   6577 C CA   . GLY C 3 129 ? -28.672 38.085 18.325  1.00 34.85 ? 129 GLY L CA   1 
ATOM   6578 C C    . GLY C 3 129 ? -28.163 36.744 17.859  1.00 37.61 ? 129 GLY L C    1 
ATOM   6579 O O    . GLY C 3 129 ? -28.751 36.175 16.939  1.00 37.91 ? 129 GLY L O    1 
ATOM   6580 H H    . GLY C 3 129 ? -28.353 38.194 20.262  1.00 46.48 ? 129 GLY L H    1 
ATOM   6581 H HA2  . GLY C 3 129 ? -29.630 38.004 18.453  1.00 41.88 ? 129 GLY L HA2  1 
ATOM   6582 H HA3  . GLY C 3 129 ? -28.501 38.723 17.615  1.00 41.88 ? 129 GLY L HA3  1 
ATOM   6583 N N    . THR C 3 130 ? -27.129 36.190 18.470  1.00 38.10 ? 130 THR L N    1 
ATOM   6584 C CA   . THR C 3 130 ? -26.603 34.887 18.079  1.00 34.46 ? 130 THR L CA   1 
ATOM   6585 C C    . THR C 3 130 ? -26.649 33.945 19.276  1.00 28.33 ? 130 THR L C    1 
ATOM   6586 O O    . THR C 3 130 ? -26.655 34.385 20.428  1.00 26.91 ? 130 THR L O    1 
ATOM   6587 C CB   . THR C 3 130 ? -25.171 35.022 17.534  1.00 35.03 ? 130 THR L CB   1 
ATOM   6588 O OG1  . THR C 3 130 ? -25.228 35.558 16.203  1.00 40.34 ? 130 THR L OG1  1 
ATOM   6589 C CG2  . THR C 3 130 ? -24.483 33.677 17.496  1.00 31.82 ? 130 THR L CG2  1 
ATOM   6590 H H    . THR C 3 130 ? -26.706 36.553 19.125  1.00 45.79 ? 130 THR L H    1 
ATOM   6591 H HA   . THR C 3 130 ? -27.146 34.493 17.378  1.00 41.42 ? 130 THR L HA   1 
ATOM   6592 H HB   . THR C 3 130 ? -24.656 35.609 18.109  1.00 42.10 ? 130 THR L HB   1 
ATOM   6593 H HG1  . THR C 3 130 ? -25.709 35.071 15.717  1.00 48.47 ? 130 THR L HG1  1 
ATOM   6594 H HG21 . THR C 3 130 ? -23.680 33.730 16.954  1.00 38.25 ? 130 THR L HG21 1 
ATOM   6595 H HG22 . THR C 3 130 ? -24.240 33.403 18.394  1.00 38.25 ? 130 THR L HG22 1 
ATOM   6596 H HG23 . THR C 3 130 ? -25.077 33.011 17.114  1.00 38.25 ? 130 THR L HG23 1 
ATOM   6597 N N    . ALA C 3 131 ? -26.717 32.645 19.005  1.00 26.24 ? 131 ALA L N    1 
ATOM   6598 C CA   . ALA C 3 131 ? -26.756 31.625 20.036  1.00 22.04 ? 131 ALA L CA   1 
ATOM   6599 C C    . ALA C 3 131 ? -25.632 30.641 19.772  1.00 24.71 ? 131 ALA L C    1 
ATOM   6600 O O    . ALA C 3 131 ? -25.617 29.978 18.726  1.00 25.19 ? 131 ALA L O    1 
ATOM   6601 C CB   . ALA C 3 131 ? -28.098 30.903 20.049  1.00 28.78 ? 131 ALA L CB   1 
ATOM   6602 H H    . ALA C 3 131 ? -26.743 32.325 18.207  1.00 31.55 ? 131 ALA L H    1 
ATOM   6603 H HA   . ALA C 3 131 ? -26.623 32.034 20.905  1.00 26.51 ? 131 ALA L HA   1 
ATOM   6604 H HB1  . ALA C 3 131 ? -28.003 30.066 20.530  1.00 34.59 ? 131 ALA L HB1  1 
ATOM   6605 H HB2  . ALA C 3 131 ? -28.755 31.465 20.490  1.00 34.59 ? 131 ALA L HB2  1 
ATOM   6606 H HB3  . ALA C 3 131 ? -28.372 30.730 19.134  1.00 34.59 ? 131 ALA L HB3  1 
ATOM   6607 N N    . SER C 3 132 ? -24.703 30.542 20.715  1.00 24.77 ? 132 SER L N    1 
ATOM   6608 C CA   . SER C 3 132 ? -23.662 29.528 20.688  1.00 23.42 ? 132 SER L CA   1 
ATOM   6609 C C    . SER C 3 132 ? -24.024 28.417 21.668  1.00 22.46 ? 132 SER L C    1 
ATOM   6610 O O    . SER C 3 132 ? -24.277 28.682 22.853  1.00 23.50 ? 132 SER L O    1 
ATOM   6611 C CB   . SER C 3 132 ? -22.334 30.168 21.076  1.00 19.49 ? 132 SER L CB   1 
ATOM   6612 O OG   . SER C 3 132 ? -21.888 31.109 20.110  1.00 21.60 ? 132 SER L OG   1 
ATOM   6613 H H    . SER C 3 132 ? -24.655 31.065 21.397  1.00 29.78 ? 132 SER L H    1 
ATOM   6614 H HA   . SER C 3 132 ? -23.580 29.134 19.805  1.00 28.17 ? 132 SER L HA   1 
ATOM   6615 H HB2  . SER C 3 132 ? -22.445 30.624 21.925  1.00 23.45 ? 132 SER L HB2  1 
ATOM   6616 H HB3  . SER C 3 132 ? -21.665 29.470 21.159  1.00 23.45 ? 132 SER L HB3  1 
ATOM   6617 H HG   . SER C 3 132 ? -21.082 31.301 20.247  1.00 25.98 ? 132 SER L HG   1 
ATOM   6618 N N    . VAL C 3 133 ? -24.074 27.186 21.184  1.00 19.13 ? 133 VAL L N    1 
ATOM   6619 C CA   . VAL C 3 133 ? -24.307 26.017 22.017  1.00 20.34 ? 133 VAL L CA   1 
ATOM   6620 C C    . VAL C 3 133 ? -23.027 25.208 22.061  1.00 22.42 ? 133 VAL L C    1 
ATOM   6621 O O    . VAL C 3 133 ? -22.469 24.876 21.014  1.00 21.88 ? 133 VAL L O    1 
ATOM   6622 C CB   . VAL C 3 133 ? -25.468 25.159 21.486  1.00 24.14 ? 133 VAL L CB   1 
ATOM   6623 C CG1  . VAL C 3 133 ? -25.978 24.238 22.564  1.00 24.63 ? 133 VAL L CG1  1 
ATOM   6624 C CG2  . VAL C 3 133 ? -26.556 26.069 20.930  1.00 25.16 ? 133 VAL L CG2  1 
ATOM   6625 H H    . VAL C 3 133 ? -23.972 26.997 20.352  1.00 23.02 ? 133 VAL L H    1 
ATOM   6626 H HA   . VAL C 3 133 ? -24.527 26.307 22.916  1.00 24.47 ? 133 VAL L HA   1 
ATOM   6627 H HB   . VAL C 3 133 ? -25.164 24.591 20.761  1.00 29.03 ? 133 VAL L HB   1 
ATOM   6628 H HG11 . VAL C 3 133 ? -26.694 23.693 22.201  1.00 29.62 ? 133 VAL L HG11 1 
ATOM   6629 H HG12 . VAL C 3 133 ? -25.251 23.672 22.865  1.00 29.62 ? 133 VAL L HG12 1 
ATOM   6630 H HG13 . VAL C 3 133 ? -26.311 24.771 23.303  1.00 29.62 ? 133 VAL L HG13 1 
ATOM   6631 H HG21 . VAL C 3 133 ? -27.358 25.545 20.778  1.00 30.25 ? 133 VAL L HG21 1 
ATOM   6632 H HG22 . VAL C 3 133 ? -26.738 26.772 21.573  1.00 30.25 ? 133 VAL L HG22 1 
ATOM   6633 H HG23 . VAL C 3 133 ? -26.249 26.454 20.095  1.00 30.25 ? 133 VAL L HG23 1 
ATOM   6634 N N    . VAL C 3 134 ? -22.563 24.882 23.261  1.00 18.72 ? 134 VAL L N    1 
ATOM   6635 C CA   . VAL C 3 134 ? -21.261 24.238 23.412  1.00 18.64 ? 134 VAL L CA   1 
ATOM   6636 C C    . VAL C 3 134 ? -21.418 22.850 24.004  1.00 20.17 ? 134 VAL L C    1 
ATOM   6637 O O    . VAL C 3 134 ? -22.079 22.664 25.032  1.00 21.09 ? 134 VAL L O    1 
ATOM   6638 C CB   . VAL C 3 134 ? -20.294 25.089 24.259  1.00 16.62 ? 134 VAL L CB   1 
ATOM   6639 C CG1  . VAL C 3 134 ? -18.960 24.365 24.421  1.00 18.22 ? 134 VAL L CG1  1 
ATOM   6640 C CG2  . VAL C 3 134 ? -20.058 26.433 23.647  1.00 20.78 ? 134 VAL L CG2  1 
ATOM   6641 H H    . VAL C 3 134 ? -22.981 25.024 23.999  1.00 22.52 ? 134 VAL L H    1 
ATOM   6642 H HA   . VAL C 3 134 ? -20.885 24.122 22.525  1.00 22.43 ? 134 VAL L HA   1 
ATOM   6643 H HB   . VAL C 3 134 ? -20.702 25.223 25.129  1.00 20.00 ? 134 VAL L HB   1 
ATOM   6644 H HG11 . VAL C 3 134 ? -18.289 25.002 24.712  1.00 21.93 ? 134 VAL L HG11 1 
ATOM   6645 H HG12 . VAL C 3 134 ? -19.060 23.664 25.083  1.00 21.93 ? 134 VAL L HG12 1 
ATOM   6646 H HG13 . VAL C 3 134 ? -18.704 23.981 23.568  1.00 21.93 ? 134 VAL L HG13 1 
ATOM   6647 H HG21 . VAL C 3 134 ? -19.454 26.937 24.216  1.00 25.00 ? 134 VAL L HG21 1 
ATOM   6648 H HG22 . VAL C 3 134 ? -19.665 26.315 22.769  1.00 25.00 ? 134 VAL L HG22 1 
ATOM   6649 H HG23 . VAL C 3 134 ? -20.905 26.899 23.571  1.00 25.00 ? 134 VAL L HG23 1 
ATOM   6650 N N    . CYS C 3 135 ? -20.735 21.892 23.392  1.00 21.15 ? 135 CYS L N    1 
ATOM   6651 C CA   . CYS C 3 135 ? -20.589 20.549 23.917  1.00 22.24 ? 135 CYS L CA   1 
ATOM   6652 C C    . CYS C 3 135 ? -19.130 20.338 24.256  1.00 19.53 ? 135 CYS L C    1 
ATOM   6653 O O    . CYS C 3 135 ? -18.248 20.556 23.416  1.00 21.76 ? 135 CYS L O    1 
ATOM   6654 C CB   . CYS C 3 135 ? -21.073 19.512 22.911  1.00 22.95 ? 135 CYS L CB   1 
ATOM   6655 S SG   . CYS C 3 135 ? -21.179 17.883 23.538  1.00 27.49 ? 135 CYS L SG   1 
ATOM   6656 H H    . CYS C 3 135 ? -20.333 22.004 22.640  1.00 25.45 ? 135 CYS L H    1 
ATOM   6657 H HA   . CYS C 3 135 ? -21.116 20.445 24.724  1.00 26.75 ? 135 CYS L HA   1 
ATOM   6658 H HB2  . CYS C 3 135 ? -21.959 19.767 22.608  1.00 27.60 ? 135 CYS L HB2  1 
ATOM   6659 H HB3  . CYS C 3 135 ? -20.457 19.498 22.162  1.00 27.60 ? 135 CYS L HB3  1 
ATOM   6660 N N    . LEU C 3 136 ? -18.889 19.911 25.477  1.00 20.12 ? 136 LEU L N    1 
ATOM   6661 C CA   . LEU C 3 136 ? -17.552 19.643 25.963  1.00 17.52 ? 136 LEU L CA   1 
ATOM   6662 C C    . LEU C 3 136 ? -17.367 18.148 26.160  1.00 21.16 ? 136 LEU L C    1 
ATOM   6663 O O    . LEU C 3 136 ? -18.179 17.509 26.827  1.00 17.41 ? 136 LEU L O    1 
ATOM   6664 C CB   . LEU C 3 136 ? -17.284 20.390 27.266  1.00 20.82 ? 136 LEU L CB   1 
ATOM   6665 C CG   . LEU C 3 136 ? -16.047 19.948 28.059  1.00 17.61 ? 136 LEU L CG   1 
ATOM   6666 C CD1  . LEU C 3 136 ? -14.757 20.362 27.411  1.00 16.19 ? 136 LEU L CD1  1 
ATOM   6667 C CD2  . LEU C 3 136 ? -16.145 20.499 29.496  1.00 18.75 ? 136 LEU L CD2  1 
ATOM   6668 H H    . LEU C 3 136 ? -19.503 19.765 26.061  1.00 24.20 ? 136 LEU L H    1 
ATOM   6669 H HA   . LEU C 3 136 ? -16.904 19.941 25.305  1.00 21.08 ? 136 LEU L HA   1 
ATOM   6670 H HB2  . LEU C 3 136 ? -17.169 21.330 27.056  1.00 25.05 ? 136 LEU L HB2  1 
ATOM   6671 H HB3  . LEU C 3 136 ? -18.054 20.271 27.845  1.00 25.05 ? 136 LEU L HB3  1 
ATOM   6672 H HG   . LEU C 3 136 ? -16.027 18.978 28.082  1.00 21.20 ? 136 LEU L HG   1 
ATOM   6673 H HD11 . LEU C 3 136 ? -14.018 19.951 27.887  1.00 19.48 ? 136 LEU L HD11 1 
ATOM   6674 H HD12 . LEU C 3 136 ? -14.760 20.068 26.486  1.00 19.48 ? 136 LEU L HD12 1 
ATOM   6675 H HD13 . LEU C 3 136 ? -14.680 21.328 27.451  1.00 19.48 ? 136 LEU L HD13 1 
ATOM   6676 H HD21 . LEU C 3 136 ? -15.295 20.369 29.944  1.00 22.57 ? 136 LEU L HD21 1 
ATOM   6677 H HD22 . LEU C 3 136 ? -16.357 21.445 29.458  1.00 22.57 ? 136 LEU L HD22 1 
ATOM   6678 H HD23 . LEU C 3 136 ? -16.845 20.022 29.970  1.00 22.57 ? 136 LEU L HD23 1 
ATOM   6679 N N    . LEU C 3 137 ? -16.295 17.602 25.581  1.00 16.49 ? 137 LEU L N    1 
ATOM   6680 C CA   . LEU C 3 137 ? -15.837 16.244 25.871  1.00 16.96 ? 137 LEU L CA   1 
ATOM   6681 C C    . LEU C 3 137 ? -14.534 16.364 26.636  1.00 16.96 ? 137 LEU L C    1 
ATOM   6682 O O    . LEU C 3 137 ? -13.554 16.892 26.093  1.00 16.90 ? 137 LEU L O    1 
ATOM   6683 C CB   . LEU C 3 137 ? -15.579 15.428 24.609  1.00 17.77 ? 137 LEU L CB   1 
ATOM   6684 C CG   . LEU C 3 137 ? -16.725 15.003 23.717  1.00 17.03 ? 137 LEU L CG   1 
ATOM   6685 C CD1  . LEU C 3 137 ? -17.624 16.165 23.348  1.00 22.15 ? 137 LEU L CD1  1 
ATOM   6686 C CD2  . LEU C 3 137 ? -16.177 14.258 22.466  1.00 22.40 ? 137 LEU L CD2  1 
ATOM   6687 H H    . LEU C 3 137 ? -15.806 18.010 25.003  1.00 19.84 ? 137 LEU L H    1 
ATOM   6688 H HA   . LEU C 3 137 ? -16.519 15.791 26.392  1.00 20.42 ? 137 LEU L HA   1 
ATOM   6689 H HB2  . LEU C 3 137 ? -14.985 15.951 24.049  1.00 21.39 ? 137 LEU L HB2  1 
ATOM   6690 H HB3  . LEU C 3 137 ? -15.138 14.609 24.886  1.00 21.39 ? 137 LEU L HB3  1 
ATOM   6691 H HG   . LEU C 3 137 ? -17.292 14.385 24.205  1.00 20.50 ? 137 LEU L HG   1 
ATOM   6692 H HD11 . LEU C 3 137 ? -18.253 15.875 22.668  1.00 26.64 ? 137 LEU L HD11 1 
ATOM   6693 H HD12 . LEU C 3 137 ? -18.104 16.457 24.139  1.00 26.64 ? 137 LEU L HD12 1 
ATOM   6694 H HD13 . LEU C 3 137 ? -17.079 16.891 23.006  1.00 26.64 ? 137 LEU L HD13 1 
ATOM   6695 H HD21 . LEU C 3 137 ? -16.903 14.119 21.838  1.00 26.94 ? 137 LEU L HD21 1 
ATOM   6696 H HD22 . LEU C 3 137 ? -15.483 14.798 22.056  1.00 26.94 ? 137 LEU L HD22 1 
ATOM   6697 H HD23 . LEU C 3 137 ? -15.811 13.404 22.743  1.00 26.94 ? 137 LEU L HD23 1 
ATOM   6698 N N    . ASN C 3 138 ? -14.506 15.865 27.866  1.00 14.67 ? 138 ASN L N    1 
ATOM   6699 C CA   . ASN C 3 138 ? -13.411 16.145 28.799  1.00 15.24 ? 138 ASN L CA   1 
ATOM   6700 C C    . ASN C 3 138 ? -12.566 14.910 29.100  1.00 17.72 ? 138 ASN L C    1 
ATOM   6701 O O    . ASN C 3 138 ? -13.107 13.881 29.526  1.00 18.47 ? 138 ASN L O    1 
ATOM   6702 C CB   . ASN C 3 138 ? -13.924 16.655 30.142  1.00 20.74 ? 138 ASN L CB   1 
ATOM   6703 C CG   . ASN C 3 138 ? -12.876 17.471 30.890  1.00 20.37 ? 138 ASN L CG   1 
ATOM   6704 O OD1  . ASN C 3 138 ? -12.317 18.436 30.395  1.00 26.24 ? 138 ASN L OD1  1 
ATOM   6705 N ND2  . ASN C 3 138 ? -12.497 16.966 32.005  1.00 24.13 ? 138 ASN L ND2  1 
ATOM   6706 H H    . ASN C 3 138 ? -15.117 15.354 28.191  1.00 17.67 ? 138 ASN L H    1 
ATOM   6707 H HA   . ASN C 3 138 ? -12.859 16.808 28.357  1.00 18.35 ? 138 ASN L HA   1 
ATOM   6708 H HB2  . ASN C 3 138 ? -14.697 17.222 29.992  1.00 24.95 ? 138 ASN L HB2  1 
ATOM   6709 H HB3  . ASN C 3 138 ? -14.170 15.899 30.697  1.00 24.95 ? 138 ASN L HB3  1 
ATOM   6710 H HD21 . ASN C 3 138 ? -11.907 17.371 32.482  1.00 29.02 ? 138 ASN L HD21 1 
ATOM   6711 H HD22 . ASN C 3 138 ? -12.832 16.222 32.276  1.00 29.02 ? 138 ASN L HD22 1 
ATOM   6712 N N    . ASN C 3 139 ? -11.235 15.042 28.970  1.00 16.79 ? 139 ASN L N    1 
ATOM   6713 C CA   . ASN C 3 139 ? -10.224 14.071 29.422  1.00 14.97 ? 139 ASN L CA   1 
ATOM   6714 C C    . ASN C 3 139 ? -10.514 12.649 28.927  1.00 17.53 ? 139 ASN L C    1 
ATOM   6715 O O    . ASN C 3 139 ? -10.780 11.733 29.704  1.00 17.13 ? 139 ASN L O    1 
ATOM   6716 C CB   . ASN C 3 139 ? -10.065 14.054 30.948  1.00 20.37 ? 139 ASN L CB   1 
ATOM   6717 C CG   . ASN C 3 139 ? -9.781  15.427 31.544  1.00 22.94 ? 139 ASN L CG   1 
ATOM   6718 O OD1  . ASN C 3 139 ? -9.362  16.344 30.857  1.00 23.84 ? 139 ASN L OD1  1 
ATOM   6719 N ND2  . ASN C 3 139 ? -9.987  15.552 32.839  1.00 31.13 ? 139 ASN L ND2  1 
ATOM   6720 H H    . ASN C 3 139 ? -10.871 15.729 28.601  1.00 20.21 ? 139 ASN L H    1 
ATOM   6721 H HA   . ASN C 3 139 ? -9.393  14.373 29.023  1.00 18.02 ? 139 ASN L HA   1 
ATOM   6722 H HB2  . ASN C 3 139 ? -10.885 13.721 31.345  1.00 24.50 ? 139 ASN L HB2  1 
ATOM   6723 H HB3  . ASN C 3 139 ? -9.324  13.471 31.179  1.00 24.50 ? 139 ASN L HB3  1 
ATOM   6724 H HD21 . ASN C 3 139 ? -10.266 14.880 33.297  1.00 37.41 ? 139 ASN L HD21 1 
ATOM   6725 H HD22 . ASN C 3 139 ? -9.843  16.306 33.227  1.00 37.41 ? 139 ASN L HD22 1 
ATOM   6726 N N    . PHE C 3 140 ? -10.391 12.476 27.613  1.00 13.39 ? 140 PHE L N    1 
ATOM   6727 C CA   . PHE C 3 140 ? -10.668 11.205 26.972  1.00 14.34 ? 140 PHE L CA   1 
ATOM   6728 C C    . PHE C 3 140 ? -9.430  10.769 26.211  1.00 14.01 ? 140 PHE L C    1 
ATOM   6729 O O    . PHE C 3 140 ? -8.559  11.575 25.887  1.00 12.41 ? 140 PHE L O    1 
ATOM   6730 C CB   . PHE C 3 140 ? -11.859 11.296 26.038  1.00 13.93 ? 140 PHE L CB   1 
ATOM   6731 C CG   . PHE C 3 140 ? -11.708 12.220 24.917  1.00 13.86 ? 140 PHE L CG   1 
ATOM   6732 C CD1  . PHE C 3 140 ? -11.166 11.823 23.701  1.00 16.94 ? 140 PHE L CD1  1 
ATOM   6733 C CD2  . PHE C 3 140 ? -12.151 13.522 25.060  1.00 14.57 ? 140 PHE L CD2  1 
ATOM   6734 C CE1  . PHE C 3 140 ? -11.069 12.722 22.645  1.00 16.93 ? 140 PHE L CE1  1 
ATOM   6735 C CE2  . PHE C 3 140 ? -12.060 14.414 24.025  1.00 15.81 ? 140 PHE L CE2  1 
ATOM   6736 C CZ   . PHE C 3 140 ? -11.522 14.034 22.817  1.00 17.45 ? 140 PHE L CZ   1 
ATOM   6737 H H    . PHE C 3 140 ? -10.144 13.094 27.068  1.00 16.13 ? 140 PHE L H    1 
ATOM   6738 H HA   . PHE C 3 140 ? -10.880 10.533 27.638  1.00 17.27 ? 140 PHE L HA   1 
ATOM   6739 H HB2  . PHE C 3 140 ? -12.023 10.415 25.666  1.00 16.77 ? 140 PHE L HB2  1 
ATOM   6740 H HB3  . PHE C 3 140 ? -12.628 11.588 26.552  1.00 16.77 ? 140 PHE L HB3  1 
ATOM   6741 H HD1  . PHE C 3 140 ? -10.865 10.950 23.592  1.00 20.39 ? 140 PHE L HD1  1 
ATOM   6742 H HD2  . PHE C 3 140 ? -12.516 13.796 25.871  1.00 17.55 ? 140 PHE L HD2  1 
ATOM   6743 H HE1  . PHE C 3 140 ? -10.708 12.453 21.831  1.00 20.38 ? 140 PHE L HE1  1 
ATOM   6744 H HE2  . PHE C 3 140 ? -12.366 15.285 24.139  1.00 19.03 ? 140 PHE L HE2  1 
ATOM   6745 H HZ   . PHE C 3 140 ? -11.459 14.647 22.120  1.00 21.00 ? 140 PHE L HZ   1 
ATOM   6746 N N    . TYR C 3 141 ? -9.381  9.461  25.943  1.00 14.73 ? 141 TYR L N    1 
ATOM   6747 C CA   . TYR C 3 141 ? -8.284  8.868  25.189  1.00 15.67 ? 141 TYR L CA   1 
ATOM   6748 C C    . TYR C 3 141 ? -8.841  7.579  24.589  1.00 13.94 ? 141 TYR L C    1 
ATOM   6749 O O    . TYR C 3 141 ? -9.488  6.813  25.305  1.00 14.74 ? 141 TYR L O    1 
ATOM   6750 C CB   . TYR C 3 141 ? -7.059  8.551  26.024  1.00 14.28 ? 141 TYR L CB   1 
ATOM   6751 C CG   . TYR C 3 141 ? -5.951  8.046  25.135  1.00 14.30 ? 141 TYR L CG   1 
ATOM   6752 C CD1  . TYR C 3 141 ? -5.837  6.709  24.840  1.00 12.32 ? 141 TYR L CD1  1 
ATOM   6753 C CD2  . TYR C 3 141 ? -5.104  8.936  24.500  1.00 13.32 ? 141 TYR L CD2  1 
ATOM   6754 C CE1  . TYR C 3 141 ? -4.846  6.244  23.977  1.00 14.65 ? 141 TYR L CE1  1 
ATOM   6755 C CE2  . TYR C 3 141 ? -4.112  8.499  23.656  1.00 16.65 ? 141 TYR L CE2  1 
ATOM   6756 C CZ   . TYR C 3 141 ? -4.001  7.154  23.397  1.00 19.02 ? 141 TYR L CZ   1 
ATOM   6757 O OH   . TYR C 3 141 ? -3.063  6.695  22.532  1.00 19.61 ? 141 TYR L OH   1 
ATOM   6758 H H    . TYR C 3 141 ? -9.979  8.895  26.192  1.00 17.73 ? 141 TYR L H    1 
ATOM   6759 H HA   . TYR C 3 141 ? -7.994  9.483  24.498  1.00 18.86 ? 141 TYR L HA   1 
ATOM   6760 H HB2  . TYR C 3 141 ? -6.755  9.353  26.477  1.00 17.20 ? 141 TYR L HB2  1 
ATOM   6761 H HB3  . TYR C 3 141 ? -7.275  7.864  26.675  1.00 17.20 ? 141 TYR L HB3  1 
ATOM   6762 H HD1  . TYR C 3 141 ? -6.431  6.104  25.223  1.00 14.85 ? 141 TYR L HD1  1 
ATOM   6763 H HD2  . TYR C 3 141 ? -5.208  9.848  24.648  1.00 16.05 ? 141 TYR L HD2  1 
ATOM   6764 H HE1  . TYR C 3 141 ? -4.760  5.336  23.799  1.00 17.64 ? 141 TYR L HE1  1 
ATOM   6765 H HE2  . TYR C 3 141 ? -3.524  9.105  23.266  1.00 20.04 ? 141 TYR L HE2  1 
ATOM   6766 H HH   . TYR C 3 141 ? -2.509  7.302  22.360  1.00 23.59 ? 141 TYR L HH   1 
ATOM   6767 N N    . PRO C 3 142 ? -8.579  7.281  23.315  1.00 15.73 ? 142 PRO L N    1 
ATOM   6768 C CA   . PRO C 3 142 ? -7.786  8.004  22.319  1.00 16.69 ? 142 PRO L CA   1 
ATOM   6769 C C    . PRO C 3 142 ? -8.484  9.212  21.720  1.00 16.30 ? 142 PRO L C    1 
ATOM   6770 O O    . PRO C 3 142 ? -9.601  9.541  22.047  1.00 15.54 ? 142 PRO L O    1 
ATOM   6771 C CB   . PRO C 3 142 ? -7.513  6.933  21.236  1.00 20.36 ? 142 PRO L CB   1 
ATOM   6772 C CG   . PRO C 3 142 ? -8.677  5.994  21.345  1.00 15.25 ? 142 PRO L CG   1 
ATOM   6773 C CD   . PRO C 3 142 ? -9.026  5.964  22.815  1.00 16.63 ? 142 PRO L CD   1 
ATOM   6774 H HA   . PRO C 3 142 ? -6.959  8.288  22.739  1.00 20.09 ? 142 PRO L HA   1 
ATOM   6775 H HB2  . PRO C 3 142 ? -7.479  7.347  20.359  1.00 24.49 ? 142 PRO L HB2  1 
ATOM   6776 H HB3  . PRO C 3 142 ? -6.677  6.478  21.420  1.00 24.49 ? 142 PRO L HB3  1 
ATOM   6777 H HG2  . PRO C 3 142 ? -9.421  6.328  20.820  1.00 18.36 ? 142 PRO L HG2  1 
ATOM   6778 H HG3  . PRO C 3 142 ? -8.419  5.112  21.033  1.00 18.36 ? 142 PRO L HG3  1 
ATOM   6779 H HD2  . PRO C 3 142 ? -9.982  5.857  22.939  1.00 20.01 ? 142 PRO L HD2  1 
ATOM   6780 H HD3  . PRO C 3 142 ? -8.551  5.247  23.266  1.00 20.01 ? 142 PRO L HD3  1 
ATOM   6781 N N    . ARG C 3 143 ? -7.787  9.902  20.805  1.00 17.67 ? 143 ARG L N    1 
ATOM   6782 C CA   . ARG C 3 143 ? -8.230  11.193 20.278  1.00 18.16 ? 143 ARG L CA   1 
ATOM   6783 C C    . ARG C 3 143 ? -9.510  11.088 19.462  1.00 19.40 ? 143 ARG L C    1 
ATOM   6784 O O    . ARG C 3 143 ? -10.288 12.044 19.431  1.00 17.84 ? 143 ARG L O    1 
ATOM   6785 C CB   . ARG C 3 143 ? -7.146  11.788 19.384  1.00 21.67 ? 143 ARG L CB   1 
ATOM   6786 C CG   . ARG C 3 143 ? -7.664  12.833 18.341  1.00 32.65 ? 143 ARG L CG   1 
ATOM   6787 C CD   . ARG C 3 143 ? -7.830  14.187 18.996  1.00 26.43 ? 143 ARG L CD   1 
ATOM   6788 N NE   . ARG C 3 143 ? -8.365  15.230 18.106  1.00 31.50 ? 143 ARG L NE   1 
ATOM   6789 C CZ   . ARG C 3 143 ? -9.557  15.231 17.512  1.00 32.45 ? 143 ARG L CZ   1 
ATOM   6790 N NH1  . ARG C 3 143 ? -10.446 14.294 17.736  1.00 23.43 ? 143 ARG L NH1  1 
ATOM   6791 N NH2  . ARG C 3 143 ? -9.883  16.237 16.703  1.00 31.26 ? 143 ARG L NH2  1 
ATOM   6792 H H    . ARG C 3 143 ? -7.041  9.638  20.469  1.00 21.27 ? 143 ARG L H    1 
ATOM   6793 H HA   . ARG C 3 143 ? -8.393  11.774 21.038  1.00 21.85 ? 143 ARG L HA   1 
ATOM   6794 H HB2  . ARG C 3 143 ? -6.493  12.234 19.945  1.00 26.07 ? 143 ARG L HB2  1 
ATOM   6795 H HB3  . ARG C 3 143 ? -6.723  11.068 18.891  1.00 26.07 ? 143 ARG L HB3  1 
ATOM   6796 H HG2  . ARG C 3 143 ? -7.025  12.915 17.616  1.00 39.24 ? 143 ARG L HG2  1 
ATOM   6797 H HG3  . ARG C 3 143 ? -8.525  12.549 17.994  1.00 39.24 ? 143 ARG L HG3  1 
ATOM   6798 H HD2  . ARG C 3 143 ? -8.441  14.097 19.744  1.00 31.78 ? 143 ARG L HD2  1 
ATOM   6799 H HD3  . ARG C 3 143 ? -6.963  14.487 19.311  1.00 31.78 ? 143 ARG L HD3  1 
ATOM   6800 H HE   . ARG C 3 143 ? -7.857  15.907 17.954  1.00 37.86 ? 143 ARG L HE   1 
ATOM   6801 H HH11 . ARG C 3 143 ? -10.267 13.653 18.281  1.00 28.18 ? 143 ARG L HH11 1 
ATOM   6802 H HH12 . ARG C 3 143 ? -11.208 14.320 17.338  1.00 28.18 ? 143 ARG L HH12 1 
ATOM   6803 H HH21 . ARG C 3 143 ? -9.325  16.878 16.568  1.00 37.57 ? 143 ARG L HH21 1 
ATOM   6804 H HH22 . ARG C 3 143 ? -10.650 16.246 16.315  1.00 37.57 ? 143 ARG L HH22 1 
ATOM   6805 N N    . GLU C 3 144 ? -9.716  9.974  18.759  1.00 21.93 ? 144 GLU L N    1 
ATOM   6806 C CA   . GLU C 3 144 ? -10.833 9.864  17.822  1.00 22.99 ? 144 GLU L CA   1 
ATOM   6807 C C    . GLU C 3 144 ? -12.155 10.019 18.556  1.00 21.10 ? 144 GLU L C    1 
ATOM   6808 O O    . GLU C 3 144 ? -12.379 9.406  19.599  1.00 21.29 ? 144 GLU L O    1 
ATOM   6809 C CB   . GLU C 3 144 ? -10.790 8.510  17.115  1.00 23.00 ? 144 GLU L CB   1 
ATOM   6810 C CG   . GLU C 3 144 ? -9.639  8.271  16.130  1.00 31.68 ? 144 GLU L CG   1 
ATOM   6811 C CD   . GLU C 3 144 ? -8.321  7.892  16.796  1.00 30.06 ? 144 GLU L CD   1 
ATOM   6812 O OE1  . GLU C 3 144 ? -8.319  7.602  18.011  1.00 25.97 ? 144 GLU L OE1  1 
ATOM   6813 O OE2  . GLU C 3 144 ? -7.300  7.829  16.073  1.00 31.78 ? 144 GLU L OE2  1 
ATOM   6814 H H    . GLU C 3 144 ? -9.225  9.270  18.806  1.00 26.38 ? 144 GLU L H    1 
ATOM   6815 H HA   . GLU C 3 144 ? -10.762 10.566 17.156  1.00 27.65 ? 144 GLU L HA   1 
ATOM   6816 H HB2  . GLU C 3 144 ? -10.726 7.820  17.795  1.00 27.66 ? 144 GLU L HB2  1 
ATOM   6817 H HB3  . GLU C 3 144 ? -11.615 8.407  16.615  1.00 27.66 ? 144 GLU L HB3  1 
ATOM   6818 H HG2  . GLU C 3 144 ? -9.886  7.549  15.532  1.00 38.08 ? 144 GLU L HG2  1 
ATOM   6819 H HG3  . GLU C 3 144 ? -9.489  9.085  15.623  1.00 38.08 ? 144 GLU L HG3  1 
ATOM   6820 N N    . ALA C 3 145 ? -13.011 10.877 18.034  1.00 22.84 ? 145 ALA L N    1 
ATOM   6821 C CA   . ALA C 3 145 ? -14.318 11.078 18.640  1.00 22.64 ? 145 ALA L CA   1 
ATOM   6822 C C    . ALA C 3 145 ? -15.270 11.680 17.609  1.00 22.19 ? 145 ALA L C    1 
ATOM   6823 O O    . ALA C 3 145 ? -14.862 12.461 16.739  1.00 29.22 ? 145 ALA L O    1 
ATOM   6824 C CB   . ALA C 3 145 ? -14.220 11.962 19.886  1.00 24.26 ? 145 ALA L CB   1 
ATOM   6825 H H    . ALA C 3 145 ? -12.862 11.354 17.334  1.00 27.47 ? 145 ALA L H    1 
ATOM   6826 H HA   . ALA C 3 145 ? -14.688 10.221 18.906  1.00 27.23 ? 145 ALA L HA   1 
ATOM   6827 H HB1  . ALA C 3 145 ? -15.111 12.103 20.244  1.00 29.17 ? 145 ALA L HB1  1 
ATOM   6828 H HB2  . ALA C 3 145 ? -13.665 11.518 20.545  1.00 29.17 ? 145 ALA L HB2  1 
ATOM   6829 H HB3  . ALA C 3 145 ? -13.825 12.813 19.639  1.00 29.17 ? 145 ALA L HB3  1 
ATOM   6830 N N    . LYS C 3 146 ? -16.534 11.284 17.721  1.00 22.48 ? 146 LYS L N    1 
ATOM   6831 C CA   . LYS C 3 146 ? -17.623 11.785 16.896  1.00 28.63 ? 146 LYS L CA   1 
ATOM   6832 C C    . LYS C 3 146 ? -18.581 12.578 17.766  1.00 22.41 ? 146 LYS L C    1 
ATOM   6833 O O    . LYS C 3 146 ? -19.080 12.054 18.762  1.00 24.03 ? 146 LYS L O    1 
ATOM   6834 C CB   . LYS C 3 146 ? -18.416 10.665 16.209  1.00 31.02 ? 146 LYS L CB   1 
ATOM   6835 H H    . LYS C 3 146 ? -16.795 10.699 18.295  1.00 27.03 ? 146 LYS L H    1 
ATOM   6836 H HA   . LYS C 3 146 ? -17.235 12.350 16.210  1.00 34.42 ? 146 LYS L HA   1 
ATOM   6837 N N    . VAL C 3 147 ? -18.835 13.824 17.393  1.00 23.78 ? 147 VAL L N    1 
ATOM   6838 C CA   . VAL C 3 147 ? -19.828 14.663 18.058  1.00 25.50 ? 147 VAL L CA   1 
ATOM   6839 C C    . VAL C 3 147 ? -20.876 15.053 17.029  1.00 25.22 ? 147 VAL L C    1 
ATOM   6840 O O    . VAL C 3 147 ? -20.550 15.695 16.022  1.00 32.67 ? 147 VAL L O    1 
ATOM   6841 C CB   . VAL C 3 147 ? -19.189 15.904 18.703  1.00 27.90 ? 147 VAL L CB   1 
ATOM   6842 C CG1  . VAL C 3 147 ? -20.176 16.617 19.584  1.00 30.13 ? 147 VAL L CG1  1 
ATOM   6843 C CG2  . VAL C 3 147 ? -17.970 15.469 19.520  1.00 29.66 ? 147 VAL L CG2  1 
ATOM   6844 H H    . VAL C 3 147 ? -18.435 14.217 16.741  1.00 28.60 ? 147 VAL L H    1 
ATOM   6845 H HA   . VAL C 3 147 ? -20.267 14.151 18.755  1.00 30.66 ? 147 VAL L HA   1 
ATOM   6846 H HB   . VAL C 3 147 ? -18.912 16.522 18.009  1.00 33.54 ? 147 VAL L HB   1 
ATOM   6847 H HG11 . VAL C 3 147 ? -19.790 17.459 19.874  1.00 36.22 ? 147 VAL L HG11 1 
ATOM   6848 H HG12 . VAL C 3 147 ? -20.988 16.782 19.080  1.00 36.22 ? 147 VAL L HG12 1 
ATOM   6849 H HG13 . VAL C 3 147 ? -20.371 16.061 20.354  1.00 36.22 ? 147 VAL L HG13 1 
ATOM   6850 H HG21 . VAL C 3 147 ? -17.760 16.161 20.166  1.00 35.65 ? 147 VAL L HG21 1 
ATOM   6851 H HG22 . VAL C 3 147 ? -18.176 14.639 19.978  1.00 35.65 ? 147 VAL L HG22 1 
ATOM   6852 H HG23 . VAL C 3 147 ? -17.218 15.337 18.920  1.00 35.65 ? 147 VAL L HG23 1 
ATOM   6853 N N    . GLN C 3 148 ? -22.115 14.601 17.237  1.00 27.44 ? 148 GLN L N    1 
ATOM   6854 C CA   . GLN C 3 148 ? -23.227 14.894 16.346  1.00 29.16 ? 148 GLN L CA   1 
ATOM   6855 C C    . GLN C 3 148 ? -24.201 15.802 17.081  1.00 25.00 ? 148 GLN L C    1 
ATOM   6856 O O    . GLN C 3 148 ? -24.592 15.509 18.213  1.00 28.13 ? 148 GLN L O    1 
ATOM   6857 C CB   . GLN C 3 148 ? -23.910 13.602 15.892  1.00 28.58 ? 148 GLN L CB   1 
ATOM   6858 H H    . GLN C 3 148 ? -22.336 14.110 17.907  1.00 32.99 ? 148 GLN L H    1 
ATOM   6859 H HA   . GLN C 3 148 ? -22.920 15.356 15.550  1.00 35.05 ? 148 GLN L HA   1 
ATOM   6860 N N    . TRP C 3 149 ? -24.574 16.906 16.448  1.00 28.24 ? 149 TRP L N    1 
ATOM   6861 C CA   . TRP C 3 149 ? -25.583 17.805 16.995  1.00 31.24 ? 149 TRP L CA   1 
ATOM   6862 C C    . TRP C 3 149 ? -26.949 17.437 16.439  1.00 35.53 ? 149 TRP L C    1 
ATOM   6863 O O    . TRP C 3 149 ? -27.093 17.227 15.229  1.00 32.98 ? 149 TRP L O    1 
ATOM   6864 C CB   . TRP C 3 149 ? -25.283 19.249 16.619  1.00 31.53 ? 149 TRP L CB   1 
ATOM   6865 C CG   . TRP C 3 149 ? -24.185 19.887 17.419  1.00 31.03 ? 149 TRP L CG   1 
ATOM   6866 C CD1  . TRP C 3 149 ? -22.912 20.116 16.991  1.00 33.29 ? 149 TRP L CD1  1 
ATOM   6867 C CD2  . TRP C 3 149 ? -24.262 20.403 18.756  1.00 31.16 ? 149 TRP L CD2  1 
ATOM   6868 N NE1  . TRP C 3 149 ? -22.189 20.732 17.980  1.00 25.93 ? 149 TRP L NE1  1 
ATOM   6869 C CE2  . TRP C 3 149 ? -22.988 20.920 19.075  1.00 24.87 ? 149 TRP L CE2  1 
ATOM   6870 C CE3  . TRP C 3 149 ? -25.278 20.484 19.710  1.00 28.64 ? 149 TRP L CE3  1 
ATOM   6871 C CZ2  . TRP C 3 149 ? -22.704 21.512 20.306  1.00 23.67 ? 149 TRP L CZ2  1 
ATOM   6872 C CZ3  . TRP C 3 149 ? -24.997 21.055 20.935  1.00 29.99 ? 149 TRP L CZ3  1 
ATOM   6873 C CH2  . TRP C 3 149 ? -23.718 21.581 21.219  1.00 26.86 ? 149 TRP L CH2  1 
ATOM   6874 H H    . TRP C 3 149 ? -24.255 17.160 15.691  1.00 33.94 ? 149 TRP L H    1 
ATOM   6875 H HA   . TRP C 3 149 ? -25.589 17.728 17.962  1.00 37.55 ? 149 TRP L HA   1 
ATOM   6876 H HB2  . TRP C 3 149 ? -25.019 19.276 15.686  1.00 37.90 ? 149 TRP L HB2  1 
ATOM   6877 H HB3  . TRP C 3 149 ? -26.086 19.776 16.752  1.00 37.90 ? 149 TRP L HB3  1 
ATOM   6878 H HD1  . TRP C 3 149 ? -22.583 19.889 16.152  1.00 40.01 ? 149 TRP L HD1  1 
ATOM   6879 H HE1  . TRP C 3 149 ? -21.362 20.963 17.922  1.00 31.18 ? 149 TRP L HE1  1 
ATOM   6880 H HE3  . TRP C 3 149 ? -26.129 20.158 19.523  1.00 34.42 ? 149 TRP L HE3  1 
ATOM   6881 H HZ2  . TRP C 3 149 ? -21.857 21.847 20.497  1.00 28.46 ? 149 TRP L HZ2  1 
ATOM   6882 H HZ3  . TRP C 3 149 ? -25.662 21.095 21.584  1.00 36.05 ? 149 TRP L HZ3  1 
ATOM   6883 H HH2  . TRP C 3 149 ? -23.562 21.981 22.044  1.00 32.30 ? 149 TRP L HH2  1 
ATOM   6884 N N    . LYS C 3 150 ? -27.947 17.374 17.317  1.00 33.10 ? 150 LYS L N    1 
ATOM   6885 C CA   . LYS C 3 150 ? -29.337 17.259 16.897  1.00 37.60 ? 150 LYS L CA   1 
ATOM   6886 C C    . LYS C 3 150 ? -30.171 18.346 17.564  1.00 37.55 ? 150 LYS L C    1 
ATOM   6887 O O    . LYS C 3 150 ? -30.085 18.559 18.778  1.00 34.73 ? 150 LYS L O    1 
ATOM   6888 C CB   . LYS C 3 150 ? -29.901 15.867 17.218  1.00 39.79 ? 150 LYS L CB   1 
ATOM   6889 C CG   . LYS C 3 150 ? -29.477 14.823 16.232  1.00 46.13 ? 150 LYS L CG   1 
ATOM   6890 C CD   . LYS C 3 150 ? -29.766 13.438 16.754  1.00 50.12 ? 150 LYS L CD   1 
ATOM   6891 C CE   . LYS C 3 150 ? -28.700 13.011 17.749  1.00 56.76 ? 150 LYS L CE   1 
ATOM   6892 N NZ   . LYS C 3 150 ? -27.917 11.824 17.286  1.00 55.81 ? 150 LYS L NZ   1 
ATOM   6893 H H    . LYS C 3 150 ? -27.840 17.396 18.170  1.00 39.78 ? 150 LYS L H    1 
ATOM   6894 H HA   . LYS C 3 150 ? -29.392 17.396 15.938  1.00 45.18 ? 150 LYS L HA   1 
ATOM   6895 H HB2  . LYS C 3 150 ? -29.589 15.595 18.095  1.00 47.81 ? 150 LYS L HB2  1 
ATOM   6896 H HB3  . LYS C 3 150 ? -30.870 15.911 17.210  1.00 47.81 ? 150 LYS L HB3  1 
ATOM   6897 H HG2  . LYS C 3 150 ? -29.963 14.946 15.401  1.00 55.41 ? 150 LYS L HG2  1 
ATOM   6898 H HG3  . LYS C 3 150 ? -28.523 14.898 16.072  1.00 55.41 ? 150 LYS L HG3  1 
ATOM   6899 H HD2  . LYS C 3 150 ? -30.626 13.433 17.202  1.00 60.20 ? 150 LYS L HD2  1 
ATOM   6900 H HD3  . LYS C 3 150 ? -29.771 12.807 16.017  1.00 60.20 ? 150 LYS L HD3  1 
ATOM   6901 H HE2  . LYS C 3 150 ? -28.080 13.745 17.883  1.00 68.17 ? 150 LYS L HE2  1 
ATOM   6902 H HE3  . LYS C 3 150 ? -29.126 12.779 18.589  1.00 68.17 ? 150 LYS L HE3  1 
ATOM   6903 H HZ1  . LYS C 3 150 ? -27.301 11.611 17.892  1.00 67.04 ? 150 LYS L HZ1  1 
ATOM   6904 H HZ2  . LYS C 3 150 ? -28.459 11.128 17.169  1.00 67.04 ? 150 LYS L HZ2  1 
ATOM   6905 H HZ3  . LYS C 3 150 ? -27.513 12.008 16.515  1.00 67.04 ? 150 LYS L HZ3  1 
ATOM   6906 N N    . VAL C 3 151 ? -31.020 18.987 16.753  1.00 37.83 ? 151 VAL L N    1 
ATOM   6907 C CA   . VAL C 3 151 ? -31.929 19.987 17.250  1.00 39.56 ? 151 VAL L CA   1 
ATOM   6908 C C    . VAL C 3 151 ? -33.349 19.509 16.934  1.00 40.24 ? 151 VAL L C    1 
ATOM   6909 O O    . VAL C 3 151 ? -33.684 19.308 15.791  1.00 41.99 ? 151 VAL L O    1 
ATOM   6910 C CB   . VAL C 3 151 ? -31.667 21.324 16.583  1.00 40.02 ? 151 VAL L CB   1 
ATOM   6911 C CG1  . VAL C 3 151 ? -32.618 22.373 17.136  1.00 43.54 ? 151 VAL L CG1  1 
ATOM   6912 C CG2  . VAL C 3 151 ? -30.225 21.746 16.799  1.00 37.17 ? 151 VAL L CG2  1 
ATOM   6913 H H    . VAL C 3 151 ? -31.087 18.867 15.901  1.00 45.46 ? 151 VAL L H    1 
ATOM   6914 H HA   . VAL C 3 151 ? -31.833 20.101 18.214  1.00 47.54 ? 151 VAL L HA   1 
ATOM   6915 H HB   . VAL C 3 151 ? -31.819 21.239 15.620  1.00 48.08 ? 151 VAL L HB   1 
ATOM   6916 H HG11 . VAL C 3 151 ? -32.306 23.245 16.883  1.00 52.31 ? 151 VAL L HG11 1 
ATOM   6917 H HG12 . VAL C 3 151 ? -33.499 22.223 16.783  1.00 52.31 ? 151 VAL L HG12 1 
ATOM   6918 H HG13 . VAL C 3 151 ? -32.633 22.298 18.094  1.00 52.31 ? 151 VAL L HG13 1 
ATOM   6919 H HG21 . VAL C 3 151 ? -30.120 22.657 16.517  1.00 44.67 ? 151 VAL L HG21 1 
ATOM   6920 H HG22 . VAL C 3 151 ? -30.022 21.665 17.734  1.00 44.67 ? 151 VAL L HG22 1 
ATOM   6921 H HG23 . VAL C 3 151 ? -29.652 21.171 16.285  1.00 44.67 ? 151 VAL L HG23 1 
ATOM   6922 N N    . ASP C 3 152 ? -34.160 19.306 17.946  1.00 40.43 ? 152 ASP L N    1 
ATOM   6923 C CA   . ASP C 3 152 ? -35.500 18.746 17.742  1.00 45.71 ? 152 ASP L CA   1 
ATOM   6924 C C    . ASP C 3 152 ? -35.391 17.423 17.050  1.00 47.15 ? 152 ASP L C    1 
ATOM   6925 O O    . ASP C 3 152 ? -36.380 16.908 16.572  1.00 51.21 ? 152 ASP L O    1 
ATOM   6926 C CB   . ASP C 3 152 ? -36.409 19.752 17.045  1.00 44.38 ? 152 ASP L CB   1 
ATOM   6927 C CG   . ASP C 3 152 ? -37.088 20.686 18.033  1.00 42.70 ? 152 ASP L CG   1 
ATOM   6928 O OD1  . ASP C 3 152 ? -37.184 20.346 19.226  1.00 39.77 ? 152 ASP L OD1  1 
ATOM   6929 O OD2  . ASP C 3 152 ? -37.521 21.772 17.619  1.00 44.86 ? 152 ASP L OD2  1 
ATOM   6930 H H    . ASP C 3 152 ? -33.969 19.485 18.766  1.00 48.58 ? 152 ASP L H    1 
ATOM   6931 H HA   . ASP C 3 152 ? -35.874 18.543 18.621  1.00 54.91 ? 152 ASP L HA   1 
ATOM   6932 H HB2  . ASP C 3 152 ? -35.885 20.303 16.444  1.00 53.32 ? 152 ASP L HB2  1 
ATOM   6933 H HB3  . ASP C 3 152 ? -37.098 19.284 16.553  1.00 53.32 ? 152 ASP L HB3  1 
ATOM   6934 N N    . ASN C 3 153 ? -34.202 16.839 17.050  1.00 47.83 ? 153 ASN L N    1 
ATOM   6935 C CA   . ASN C 3 153 ? -33.956 15.510 16.517  1.00 45.09 ? 153 ASN L CA   1 
ATOM   6936 C C    . ASN C 3 153 ? -33.465 15.522 15.105  1.00 42.92 ? 153 ASN L C    1 
ATOM   6937 O O    . ASN C 3 153 ? -33.188 14.483 14.546  1.00 45.33 ? 153 ASN L O    1 
ATOM   6938 C CB   . ASN C 3 153 ? -35.168 14.555 16.691  1.00 48.78 ? 153 ASN L CB   1 
ATOM   6939 N N    . ALA C 3 154 ? -33.350 16.687 14.527  1.00 39.66 ? 154 ALA L N    1 
ATOM   6940 C CA   . ALA C 3 154 ? -32.783 16.738 13.228  1.00 43.86 ? 154 ALA L CA   1 
ATOM   6941 C C    . ALA C 3 154 ? -31.293 16.835 13.409  1.00 48.89 ? 154 ALA L C    1 
ATOM   6942 O O    . ALA C 3 154 ? -30.853 17.478 14.312  1.00 51.56 ? 154 ALA L O    1 
ATOM   6943 C CB   . ALA C 3 154 ? -33.267 17.926 12.471  1.00 39.27 ? 154 ALA L CB   1 
ATOM   6944 N N    . LEU C 3 155 ? -30.542 16.220 12.515  1.00 43.45 ? 155 LEU L N    1 
ATOM   6945 C CA   . LEU C 3 155 ? -29.110 16.262 12.594  1.00 42.90 ? 155 LEU L CA   1 
ATOM   6946 C C    . LEU C 3 155 ? -28.628 17.495 11.933  1.00 42.67 ? 155 LEU L C    1 
ATOM   6947 O O    . LEU C 3 155 ? -29.129 17.867 10.902  1.00 48.26 ? 155 LEU L O    1 
ATOM   6948 C CB   . LEU C 3 155 ? -28.474 15.043 11.922  1.00 45.35 ? 155 LEU L CB   1 
ATOM   6949 C CG   . LEU C 3 155 ? -26.968 15.113 11.776  1.00 47.10 ? 155 LEU L CG   1 
ATOM   6950 C CD1  . LEU C 3 155 ? -26.326 15.099 13.147  1.00 45.12 ? 155 LEU L CD1  1 
ATOM   6951 C CD2  . LEU C 3 155 ? -26.494 13.952 10.934  1.00 47.38 ? 155 LEU L CD2  1 
ATOM   6952 H H    . LEU C 3 155 ? -30.844 15.768 11.850  1.00 52.21 ? 155 LEU L H    1 
ATOM   6953 H HA   . LEU C 3 155 ? -28.828 16.279 13.532  1.00 51.54 ? 155 LEU L HA   1 
ATOM   6954 H HB2  . LEU C 3 155 ? -28.678 14.259 12.452  1.00 54.48 ? 155 LEU L HB2  1 
ATOM   6955 H HB3  . LEU C 3 155 ? -28.849 14.949 11.035  1.00 54.48 ? 155 LEU L HB3  1 
ATOM   6956 H HG   . LEU C 3 155 ? -26.711 15.930 11.323  1.00 56.59 ? 155 LEU L HG   1 
ATOM   6957 H HD11 . LEU C 3 155 ? -25.670 14.401 13.174  1.00 54.20 ? 155 LEU L HD11 1 
ATOM   6958 H HD12 . LEU C 3 155 ? -25.911 15.951 13.305  1.00 54.20 ? 155 LEU L HD12 1 
ATOM   6959 H HD13 . LEU C 3 155 ? -27.005 14.940 13.807  1.00 54.20 ? 155 LEU L HD13 1 
ATOM   6960 H HD21 . LEU C 3 155 ? -25.539 13.999 10.854  1.00 56.92 ? 155 LEU L HD21 1 
ATOM   6961 H HD22 . LEU C 3 155 ? -26.752 13.138 11.369  1.00 56.92 ? 155 LEU L HD22 1 
ATOM   6962 H HD23 . LEU C 3 155 ? -26.905 14.012 10.069  1.00 56.92 ? 155 LEU L HD23 1 
ATOM   6963 N N    . GLN C 3 156 ? -27.629 18.121 12.520  1.00 37.87 ? 156 GLN L N    1 
ATOM   6964 C CA   . GLN C 3 156 ? -27.101 19.330 11.998  1.00 34.24 ? 156 GLN L CA   1 
ATOM   6965 C C    . GLN C 3 156 ? -25.870 19.123 11.137  1.00 37.67 ? 156 GLN L C    1 
ATOM   6966 O O    . GLN C 3 156 ? -25.113 18.213 11.362  1.00 38.70 ? 156 GLN L O    1 
ATOM   6967 C CB   . GLN C 3 156 ? -26.733 20.233 13.175  1.00 35.61 ? 156 GLN L CB   1 
ATOM   6968 C CG   . GLN C 3 156 ? -27.843 20.454 14.177  1.00 38.15 ? 156 GLN L CG   1 
ATOM   6969 C CD   . GLN C 3 156 ? -29.051 21.094 13.541  1.00 35.37 ? 156 GLN L CD   1 
ATOM   6970 O OE1  . GLN C 3 156 ? -29.042 22.276 13.234  1.00 35.56 ? 156 GLN L OE1  1 
ATOM   6971 N NE2  . GLN C 3 156 ? -30.096 20.309 13.332  1.00 42.62 ? 156 GLN L NE2  1 
ATOM   6972 H H    . GLN C 3 156 ? -27.242 17.850 13.239  1.00 45.51 ? 156 GLN L H    1 
ATOM   6973 H HA   . GLN C 3 156 ? -27.776 19.795 11.466  1.00 41.15 ? 156 GLN L HA   1 
ATOM   6974 H HB2  . GLN C 3 156 ? -25.984 19.837 13.647  1.00 42.80 ? 156 GLN L HB2  1 
ATOM   6975 H HB3  . GLN C 3 156 ? -26.482 21.101 12.827  1.00 42.80 ? 156 GLN L HB3  1 
ATOM   6976 H HG2  . GLN C 3 156 ? -28.110 19.602 14.559  1.00 45.85 ? 156 GLN L HG2  1 
ATOM   6977 H HG3  . GLN C 3 156 ? -27.522 21.044 14.877  1.00 45.85 ? 156 GLN L HG3  1 
ATOM   6978 H HE21 . GLN C 3 156 ? -30.042 19.468 13.512  1.00 51.20 ? 156 GLN L HE21 1 
ATOM   6979 H HE22 . GLN C 3 156 ? -30.828 20.636 13.023  1.00 51.20 ? 156 GLN L HE22 1 
ATOM   6980 N N    . SER C 3 157 ? -25.666 19.996 10.166  1.00 33.59 ? 157 SER L N    1 
ATOM   6981 C CA   . SER C 3 157 ? -24.481 19.923 9.328   1.00 33.10 ? 157 SER L CA   1 
ATOM   6982 C C    . SER C 3 157 ? -24.110 21.321 8.887   1.00 34.89 ? 157 SER L C    1 
ATOM   6983 O O    . SER C 3 157 ? -24.980 22.108 8.502   1.00 38.72 ? 157 SER L O    1 
ATOM   6984 C CB   . SER C 3 157 ? -24.691 19.021 8.098   1.00 39.55 ? 157 SER L CB   1 
ATOM   6985 O OG   . SER C 3 157 ? -25.797 18.156 8.301   1.00 41.83 ? 157 SER L OG   1 
ATOM   6986 H H    . SER C 3 157 ? -26.210 20.630 9.959   1.00 40.37 ? 157 SER L H    1 
ATOM   6987 H HA   . SER C 3 157 ? -23.749 19.551 9.846   1.00 39.78 ? 157 SER L HA   1 
ATOM   6988 H HB2  . SER C 3 157 ? -24.862 19.578 7.322   1.00 47.52 ? 157 SER L HB2  1 
ATOM   6989 H HB3  . SER C 3 157 ? -23.893 18.489 7.954   1.00 47.52 ? 157 SER L HB3  1 
ATOM   6990 H HG   . SER C 3 157 ? -25.875 17.631 7.649   1.00 50.26 ? 157 SER L HG   1 
ATOM   6991 N N    . GLY C 3 158 ? -22.817 21.630 8.976   1.00 32.06 ? 158 GLY L N    1 
ATOM   6992 C CA   . GLY C 3 158 ? -22.275 22.872 8.481   1.00 31.70 ? 158 GLY L CA   1 
ATOM   6993 C C    . GLY C 3 158 ? -22.342 24.037 9.439   1.00 27.46 ? 158 GLY L C    1 
ATOM   6994 O O    . GLY C 3 158 ? -21.822 25.106 9.115   1.00 34.76 ? 158 GLY L O    1 
ATOM   6995 H H    . GLY C 3 158 ? -22.226 21.115 9.329   1.00 38.53 ? 158 GLY L H    1 
ATOM   6996 H HA2  . GLY C 3 158 ? -21.343 22.732 8.254   1.00 38.11 ? 158 GLY L HA2  1 
ATOM   6997 H HA3  . GLY C 3 158 ? -22.762 23.123 7.680   1.00 38.11 ? 158 GLY L HA3  1 
ATOM   6998 N N    . ASN C 3 159 ? -22.974 23.873 10.595  1.00 32.51 ? 159 ASN L N    1 
ATOM   6999 C CA   . ASN C 3 159 ? -23.158 24.963 11.539  1.00 34.02 ? 159 ASN L CA   1 
ATOM   7000 C C    . ASN C 3 159 ? -22.409 24.742 12.858  1.00 29.74 ? 159 ASN L C    1 
ATOM   7001 O O    . ASN C 3 159 ? -22.711 25.409 13.845  1.00 27.66 ? 159 ASN L O    1 
ATOM   7002 C CB   . ASN C 3 159 ? -24.663 25.173 11.789  1.00 28.88 ? 159 ASN L CB   1 
ATOM   7003 C CG   . ASN C 3 159 ? -25.377 23.916 12.254  1.00 33.61 ? 159 ASN L CG   1 
ATOM   7004 O OD1  . ASN C 3 159 ? -24.780 22.862 12.412  1.00 35.80 ? 159 ASN L OD1  1 
ATOM   7005 N ND2  . ASN C 3 159 ? -26.689 24.023 12.451  1.00 36.90 ? 159 ASN L ND2  1 
ATOM   7006 H H    . ASN C 3 159 ? -23.309 23.126 10.858  1.00 39.07 ? 159 ASN L H    1 
ATOM   7007 H HA   . ASN C 3 159 ? -22.797 25.776 11.151  1.00 40.88 ? 159 ASN L HA   1 
ATOM   7008 H HB2  . ASN C 3 159 ? -24.775 25.850 12.475  1.00 34.72 ? 159 ASN L HB2  1 
ATOM   7009 H HB3  . ASN C 3 159 ? -25.081 25.465 10.964  1.00 34.72 ? 159 ASN L HB3  1 
ATOM   7010 H HD21 . ASN C 3 159 ? -27.141 23.341 12.714  1.00 44.34 ? 159 ASN L HD21 1 
ATOM   7011 H HD22 . ASN C 3 159 ? -27.085 24.774 12.314  1.00 44.34 ? 159 ASN L HD22 1 
ATOM   7012 N N    . SER C 3 160 ? -21.444 23.823 12.897  1.00 26.36 ? 160 SER L N    1 
ATOM   7013 C CA   . SER C 3 160 ? -20.653 23.539 14.083  1.00 25.41 ? 160 SER L CA   1 
ATOM   7014 C C    . SER C 3 160 ? -19.163 23.531 13.753  1.00 32.30 ? 160 SER L C    1 
ATOM   7015 O O    . SER C 3 160 ? -18.734 23.485 12.592  1.00 25.73 ? 160 SER L O    1 
ATOM   7016 C CB   . SER C 3 160 ? -21.118 22.229 14.710  1.00 27.12 ? 160 SER L CB   1 
ATOM   7017 O OG   . SER C 3 160 ? -20.837 21.128 13.864  1.00 28.25 ? 160 SER L OG   1 
ATOM   7018 H H    . SER C 3 160 ? -21.224 23.337 12.222  1.00 31.69 ? 160 SER L H    1 
ATOM   7019 H HA   . SER C 3 160 ? -20.757 24.244 14.741  1.00 30.56 ? 160 SER L HA   1 
ATOM   7020 H HB2  . SER C 3 160 ? -20.656 22.104 15.554  1.00 32.60 ? 160 SER L HB2  1 
ATOM   7021 H HB3  . SER C 3 160 ? -22.075 22.275 14.859  1.00 32.60 ? 160 SER L HB3  1 
ATOM   7022 H HG   . SER C 3 160 ? -21.118 20.418 14.215  1.00 33.96 ? 160 SER L HG   1 
ATOM   7023 N N    . GLN C 3 161 ? -18.366 23.613 14.822  1.00 25.62 ? 161 GLN L N    1 
ATOM   7024 C CA   . GLN C 3 161 ? -16.923 23.819 14.672  1.00 28.98 ? 161 GLN L CA   1 
ATOM   7025 C C    . GLN C 3 161 ? -16.264 23.197 15.910  1.00 27.32 ? 161 GLN L C    1 
ATOM   7026 O O    . GLN C 3 161 ? -16.733 23.410 17.037  1.00 23.71 ? 161 GLN L O    1 
ATOM   7027 C CB   . GLN C 3 161 ? -16.671 25.335 14.517  1.00 36.27 ? 161 GLN L CB   1 
ATOM   7028 C CG   . GLN C 3 161 ? -15.630 25.686 13.492  1.00 37.24 ? 161 GLN L CG   1 
ATOM   7029 C CD   . GLN C 3 161 ? -15.538 27.194 13.136  1.00 33.30 ? 161 GLN L CD   1 
ATOM   7030 O OE1  . GLN C 3 161 ? -16.366 28.019 13.519  1.00 32.08 ? 161 GLN L OE1  1 
ATOM   7031 N NE2  . GLN C 3 161 ? -14.526 27.533 12.355  1.00 32.21 ? 161 GLN L NE2  1 
ATOM   7032 H H    . GLN C 3 161 ? -18.634 23.552 15.636  1.00 30.81 ? 161 GLN L H    1 
ATOM   7033 H HA   . GLN C 3 161 ? -16.530 23.381 13.900  1.00 34.84 ? 161 GLN L HA   1 
ATOM   7034 H HB2  . GLN C 3 161 ? -17.501 25.762 14.251  1.00 43.59 ? 161 GLN L HB2  1 
ATOM   7035 H HB3  . GLN C 3 161 ? -16.375 25.689 15.370  1.00 43.59 ? 161 GLN L HB3  1 
ATOM   7036 H HG2  . GLN C 3 161 ? -14.763 25.414 13.830  1.00 44.74 ? 161 GLN L HG2  1 
ATOM   7037 H HG3  . GLN C 3 161 ? -15.832 25.206 12.673  1.00 44.74 ? 161 GLN L HG3  1 
ATOM   7038 H HE21 . GLN C 3 161 ? -13.974 26.933 12.081  1.00 38.71 ? 161 GLN L HE21 1 
ATOM   7039 H HE22 . GLN C 3 161 ? -14.419 28.354 12.121  1.00 38.71 ? 161 GLN L HE22 1 
ATOM   7040 N N    . GLU C 3 162 ? -15.240 22.363 15.711  1.00 21.46 ? 162 GLU L N    1 
ATOM   7041 C CA   . GLU C 3 162 ? -14.572 21.667 16.807  1.00 21.58 ? 162 GLU L CA   1 
ATOM   7042 C C    . GLU C 3 162 ? -13.174 22.221 17.061  1.00 22.34 ? 162 GLU L C    1 
ATOM   7043 O O    . GLU C 3 162 ? -12.518 22.759 16.166  1.00 22.50 ? 162 GLU L O    1 
ATOM   7044 C CB   . GLU C 3 162 ? -14.439 20.157 16.532  1.00 23.75 ? 162 GLU L CB   1 
ATOM   7045 C CG   . GLU C 3 162 ? -15.727 19.405 16.548  1.00 29.13 ? 162 GLU L CG   1 
ATOM   7046 C CD   . GLU C 3 162 ? -15.551 17.897 16.308  1.00 29.74 ? 162 GLU L CD   1 
ATOM   7047 O OE1  . GLU C 3 162 ? -14.389 17.443 16.101  1.00 29.34 ? 162 GLU L OE1  1 
ATOM   7048 O OE2  . GLU C 3 162 ? -16.586 17.184 16.336  1.00 32.03 ? 162 GLU L OE2  1 
ATOM   7049 H H    . GLU C 3 162 ? -14.911 22.184 14.937  1.00 25.82 ? 162 GLU L H    1 
ATOM   7050 H HA   . GLU C 3 162 ? -15.114 21.805 17.600  1.00 25.96 ? 162 GLU L HA   1 
ATOM   7051 H HB2  . GLU C 3 162 ? -14.042 20.038 15.655  1.00 28.57 ? 162 GLU L HB2  1 
ATOM   7052 H HB3  . GLU C 3 162 ? -13.865 19.770 17.211  1.00 28.57 ? 162 GLU L HB3  1 
ATOM   7053 H HG2  . GLU C 3 162 ? -16.148 19.521 17.414  1.00 35.02 ? 162 GLU L HG2  1 
ATOM   7054 H HG3  . GLU C 3 162 ? -16.304 19.753 15.850  1.00 35.02 ? 162 GLU L HG3  1 
ATOM   7055 N N    . SER C 3 163 ? -12.723 22.054 18.308  1.00 17.28 ? 163 SER L N    1 
ATOM   7056 C CA   . SER C 3 163 ? -11.367 22.374 18.716  1.00 18.70 ? 163 SER L CA   1 
ATOM   7057 C C    . SER C 3 163 ? -10.906 21.357 19.746  1.00 17.51 ? 163 SER L C    1 
ATOM   7058 O O    . SER C 3 163 ? -11.685 20.912 20.587  1.00 17.56 ? 163 SER L O    1 
ATOM   7059 C CB   . SER C 3 163 ? -11.312 23.785 19.294  1.00 20.26 ? 163 SER L CB   1 
ATOM   7060 O OG   . SER C 3 163 ? -9.972  24.145 19.565  1.00 25.04 ? 163 SER L OG   1 
ATOM   7061 H H    . SER C 3 163 ? -13.204 21.748 18.952  1.00 20.80 ? 163 SER L H    1 
ATOM   7062 H HA   . SER C 3 163 ? -10.763 22.319 17.959  1.00 22.50 ? 163 SER L HA   1 
ATOM   7063 H HB2  . SER C 3 163 ? -11.685 24.408 18.650  1.00 24.38 ? 163 SER L HB2  1 
ATOM   7064 H HB3  . SER C 3 163 ? -11.823 23.813 20.118  1.00 24.38 ? 163 SER L HB3  1 
ATOM   7065 H HG   . SER C 3 163 ? -9.947  24.892 19.949  1.00 30.11 ? 163 SER L HG   1 
ATOM   7066 N N    . VAL C 3 164 ? -9.638  21.007 19.703  1.00 16.01 ? 164 VAL L N    1 
ATOM   7067 C CA   . VAL C 3 164 ? -9.105  19.953 20.557  1.00 15.37 ? 164 VAL L CA   1 
ATOM   7068 C C    . VAL C 3 164 ? -7.819  20.445 21.200  1.00 11.76 ? 164 VAL L C    1 
ATOM   7069 O O    . VAL C 3 164 ? -6.990  21.080 20.543  1.00 16.56 ? 164 VAL L O    1 
ATOM   7070 C CB   . VAL C 3 164 ? -8.872  18.643 19.763  1.00 19.38 ? 164 VAL L CB   1 
ATOM   7071 C CG1  . VAL C 3 164 ? -7.761  18.796 18.736  1.00 25.74 ? 164 VAL L CG1  1 
ATOM   7072 C CG2  . VAL C 3 164 ? -8.513  17.508 20.717  1.00 17.51 ? 164 VAL L CG2  1 
ATOM   7073 H H    . VAL C 3 164 ? -9.055  21.367 19.183  1.00 19.28 ? 164 VAL L H    1 
ATOM   7074 H HA   . VAL C 3 164 ? -9.737  19.764 21.268  1.00 18.51 ? 164 VAL L HA   1 
ATOM   7075 H HB   . VAL C 3 164 ? -9.694  18.433 19.293  1.00 23.31 ? 164 VAL L HB   1 
ATOM   7076 H HG11 . VAL C 3 164 ? -7.668  17.964 18.246  1.00 30.95 ? 164 VAL L HG11 1 
ATOM   7077 H HG12 . VAL C 3 164 ? -7.992  19.515 18.127  1.00 30.95 ? 164 VAL L HG12 1 
ATOM   7078 H HG13 . VAL C 3 164 ? -6.933  19.004 19.195  1.00 30.95 ? 164 VAL L HG13 1 
ATOM   7079 H HG21 . VAL C 3 164 ? -7.834  16.952 20.304  1.00 21.07 ? 164 VAL L HG21 1 
ATOM   7080 H HG22 . VAL C 3 164 ? -8.174  17.886 21.544  1.00 21.07 ? 164 VAL L HG22 1 
ATOM   7081 H HG23 . VAL C 3 164 ? -9.308  16.982 20.895  1.00 21.07 ? 164 VAL L HG23 1 
ATOM   7082 N N    . THR C 3 165 ? -7.605  20.078 22.467  1.00 13.50 ? 165 THR L N    1 
ATOM   7083 C CA   . THR C 3 165 ? -6.359  20.407 23.140  1.00 11.93 ? 165 THR L CA   1 
ATOM   7084 C C    . THR C 3 165 ? -5.248  19.449 22.716  1.00 14.25 ? 165 THR L C    1 
ATOM   7085 O O    . THR C 3 165 ? -5.482  18.372 22.166  1.00 14.14 ? 165 THR L O    1 
ATOM   7086 C CB   . THR C 3 165 ? -6.528  20.305 24.648  1.00 17.76 ? 165 THR L CB   1 
ATOM   7087 O OG1  . THR C 3 165 ? -7.032  18.996 24.941  1.00 15.01 ? 165 THR L OG1  1 
ATOM   7088 C CG2  . THR C 3 165 ? -7.496  21.364 25.166  1.00 21.18 ? 165 THR L CG2  1 
ATOM   7089 H H    . THR C 3 165 ? -8.166  19.641 22.950  1.00 16.27 ? 165 THR L H    1 
ATOM   7090 H HA   . THR C 3 165 ? -6.113  21.314 22.900  1.00 14.37 ? 165 THR L HA   1 
ATOM   7091 H HB   . THR C 3 165 ? -5.681  20.452 25.097  1.00 21.37 ? 165 THR L HB   1 
ATOM   7092 H HG1  . THR C 3 165 ? -7.390  18.990 25.701  1.00 18.07 ? 165 THR L HG1  1 
ATOM   7093 H HG21 . THR C 3 165 ? -7.554  21.316 26.133  1.00 25.47 ? 165 THR L HG21 1 
ATOM   7094 H HG22 . THR C 3 165 ? -7.187  22.248 24.913  1.00 25.47 ? 165 THR L HG22 1 
ATOM   7095 H HG23 . THR C 3 165 ? -8.379  21.220 24.790  1.00 25.47 ? 165 THR L HG23 1 
ATOM   7096 N N    . GLU C 3 166 ? -4.031  19.836 23.012  1.00 16.63 ? 166 GLU L N    1 
ATOM   7097 C CA   . GLU C 3 166 ? -2.916  18.927 22.915  1.00 14.50 ? 166 GLU L CA   1 
ATOM   7098 C C    . GLU C 3 166 ? -2.981  17.951 24.085  1.00 17.10 ? 166 GLU L C    1 
ATOM   7099 O O    . GLU C 3 166 ? -3.638  18.193 25.116  1.00 17.31 ? 166 GLU L O    1 
ATOM   7100 C CB   . GLU C 3 166 ? -1.616  19.713 22.896  1.00 17.22 ? 166 GLU L CB   1 
ATOM   7101 C CG   . GLU C 3 166 ? -1.452  20.495 21.625  1.00 23.22 ? 166 GLU L CG   1 
ATOM   7102 C CD   . GLU C 3 166 ? -1.519  19.591 20.378  1.00 32.21 ? 166 GLU L CD   1 
ATOM   7103 O OE1  . GLU C 3 166 ? -0.569  18.795 20.179  1.00 31.36 ? 166 GLU L OE1  1 
ATOM   7104 O OE2  . GLU C 3 166 ? -2.535  19.661 19.625  1.00 29.85 ? 166 GLU L OE2  1 
ATOM   7105 H H    . GLU C 3 166 ? -3.821  20.628 23.275  1.00 20.01 ? 166 GLU L H    1 
ATOM   7106 H HA   . GLU C 3 166 ? -2.939  18.410 22.095  1.00 17.46 ? 166 GLU L HA   1 
ATOM   7107 H HB2  . GLU C 3 166 ? -1.609  20.336 23.640  1.00 20.73 ? 166 GLU L HB2  1 
ATOM   7108 H HB3  . GLU C 3 166 ? -0.870  19.097 22.973  1.00 20.73 ? 166 GLU L HB3  1 
ATOM   7109 H HG2  . GLU C 3 166 ? -2.162  21.153 21.561  1.00 27.92 ? 166 GLU L HG2  1 
ATOM   7110 H HG3  . GLU C 3 166 ? -0.589  20.938 21.632  1.00 27.92 ? 166 GLU L HG3  1 
ATOM   7111 N N    . GLN C 3 167 ? -2.267  16.833 23.914  1.00 16.55 ? 167 GLN L N    1 
ATOM   7112 C CA   . GLN C 3 167 ? -2.239  15.798 24.928  1.00 15.39 ? 167 GLN L CA   1 
ATOM   7113 C C    . GLN C 3 167 ? -1.837  16.400 26.273  1.00 15.46 ? 167 GLN L C    1 
ATOM   7114 O O    . GLN C 3 167 ? -0.825  17.096 26.375  1.00 16.60 ? 167 GLN L O    1 
ATOM   7115 C CB   . GLN C 3 167 ? -1.252  14.702 24.496  1.00 19.77 ? 167 GLN L CB   1 
ATOM   7116 C CG   . GLN C 3 167 ? -1.652  13.405 25.008  1.00 21.10 ? 167 GLN L CG   1 
ATOM   7117 C CD   . GLN C 3 167 ? -0.962  12.221 24.382  1.00 21.32 ? 167 GLN L CD   1 
ATOM   7118 O OE1  . GLN C 3 167 ? 0.030   12.337 23.659  1.00 15.59 ? 167 GLN L OE1  1 
ATOM   7119 N NE2  . GLN C 3 167 ? -1.504  11.054 24.649  1.00 18.00 ? 167 GLN L NE2  1 
ATOM   7120 H H    . GLN C 3 167 ? -1.793  16.658 23.218  1.00 19.92 ? 167 GLN L H    1 
ATOM   7121 H HA   . GLN C 3 167 ? -3.114  15.393 25.030  1.00 18.53 ? 167 GLN L HA   1 
ATOM   7122 H HB2  . GLN C 3 167 ? -1.226  14.656 23.528  1.00 23.78 ? 167 GLN L HB2  1 
ATOM   7123 H HB3  . GLN C 3 167 ? -0.369  14.910 24.842  1.00 23.78 ? 167 GLN L HB3  1 
ATOM   7124 H HG2  . GLN C 3 167 ? -1.463  13.379 25.959  1.00 25.38 ? 167 GLN L HG2  1 
ATOM   7125 H HG3  . GLN C 3 167 ? -2.604  13.297 24.857  1.00 25.38 ? 167 GLN L HG3  1 
ATOM   7126 H HE21 . GLN C 3 167 ? -2.203  11.009 25.149  1.00 21.66 ? 167 GLN L HE21 1 
ATOM   7127 H HE22 . GLN C 3 167 ? -1.161  10.336 24.324  1.00 21.66 ? 167 GLN L HE22 1 
ATOM   7128 N N    . ASP C 3 168 ? -2.604  16.093 27.316  1.00 15.65 ? 168 ASP L N    1 
ATOM   7129 C CA   . ASP C 3 168 ? -2.361  16.663 28.645  1.00 18.58 ? 168 ASP L CA   1 
ATOM   7130 C C    . ASP C 3 168 ? -1.063  16.153 29.240  1.00 20.57 ? 168 ASP L C    1 
ATOM   7131 O O    . ASP C 3 168 ? -0.726  14.970 29.141  1.00 19.78 ? 168 ASP L O    1 
ATOM   7132 C CB   . ASP C 3 168 ? -3.544  16.351 29.560  1.00 18.14 ? 168 ASP L CB   1 
ATOM   7133 C CG   . ASP C 3 168 ? -3.408  16.938 30.939  1.00 24.37 ? 168 ASP L CG   1 
ATOM   7134 O OD1  . ASP C 3 168 ? -2.762  16.357 31.816  1.00 23.16 ? 168 ASP L OD1  1 
ATOM   7135 O OD2  . ASP C 3 168 ? -3.866  18.078 31.111  1.00 28.01 ? 168 ASP L OD2  1 
ATOM   7136 H H    . ASP C 3 168 ? -3.274  15.555 27.285  1.00 18.84 ? 168 ASP L H    1 
ATOM   7137 H HA   . ASP C 3 168 ? -2.275  17.627 28.575  1.00 22.36 ? 168 ASP L HA   1 
ATOM   7138 H HB2  . ASP C 3 168 ? -4.351  16.712 29.162  1.00 21.83 ? 168 ASP L HB2  1 
ATOM   7139 H HB3  . ASP C 3 168 ? -3.622  15.389 29.654  1.00 21.83 ? 168 ASP L HB3  1 
ATOM   7140 N N    . SER C 3 169 ? -0.312  17.075 29.844  1.00 21.35 ? 169 SER L N    1 
ATOM   7141 C CA   . SER C 3 169 ? 1.029   16.722 30.289  1.00 26.53 ? 169 SER L CA   1 
ATOM   7142 C C    . SER C 3 169 ? 1.001   15.832 31.521  1.00 22.38 ? 169 SER L C    1 
ATOM   7143 O O    . SER C 3 169 ? 1.992   15.158 31.797  1.00 31.96 ? 169 SER L O    1 
ATOM   7144 C CB   . SER C 3 169 ? 1.834   17.996 30.578  1.00 27.24 ? 169 SER L CB   1 
ATOM   7145 O OG   . SER C 3 169 ? 1.293   18.622 31.720  1.00 34.09 ? 169 SER L OG   1 
ATOM   7146 H H    . SER C 3 169 ? -0.551  17.886 30.002  1.00 25.68 ? 169 SER L H    1 
ATOM   7147 H HA   . SER C 3 169 ? 1.482   16.238 29.581  1.00 31.90 ? 169 SER L HA   1 
ATOM   7148 H HB2  . SER C 3 169 ? 2.761   17.763 30.744  1.00 32.74 ? 169 SER L HB2  1 
ATOM   7149 H HB3  . SER C 3 169 ? 1.774   18.597 29.819  1.00 32.74 ? 169 SER L HB3  1 
ATOM   7150 H HG   . SER C 3 169 ? 1.553   19.420 31.761  1.00 40.97 ? 169 SER L HG   1 
ATOM   7151 N N    . LYS C 3 170 ? -0.103  15.813 32.260  1.00 23.33 ? 170 LYS L N    1 
ATOM   7152 C CA   . LYS C 3 170 ? -0.198  14.997 33.461  1.00 25.47 ? 170 LYS L CA   1 
ATOM   7153 C C    . LYS C 3 170 ? -0.865  13.654 33.207  1.00 25.15 ? 170 LYS L C    1 
ATOM   7154 O O    . LYS C 3 170 ? -0.368  12.627 33.668  1.00 29.82 ? 170 LYS L O    1 
ATOM   7155 C CB   . LYS C 3 170 ? -0.959  15.757 34.549  1.00 27.70 ? 170 LYS L CB   1 
ATOM   7156 H H    . LYS C 3 170 ? -0.812  16.267 32.084  1.00 28.06 ? 170 LYS L H    1 
ATOM   7157 H HA   . LYS C 3 170 ? 0.695   14.820 33.798  1.00 30.62 ? 170 LYS L HA   1 
ATOM   7158 N N    . ASP C 3 171 ? -1.951  13.622 32.444  1.00 20.88 ? 171 ASP L N    1 
ATOM   7159 C CA   . ASP C 3 171 ? -2.721  12.398 32.291  1.00 16.11 ? 171 ASP L CA   1 
ATOM   7160 C C    . ASP C 3 171 ? -2.824  11.930 30.838  1.00 18.53 ? 171 ASP L C    1 
ATOM   7161 O O    . ASP C 3 171 ? -3.526  10.950 30.561  1.00 14.34 ? 171 ASP L O    1 
ATOM   7162 C CB   . ASP C 3 171 ? -4.089  12.612 32.964  1.00 22.29 ? 171 ASP L CB   1 
ATOM   7163 C CG   . ASP C 3 171 ? -5.092  13.363 32.116  1.00 19.91 ? 171 ASP L CG   1 
ATOM   7164 O OD1  . ASP C 3 171 ? -4.806  13.805 30.984  1.00 16.92 ? 171 ASP L OD1  1 
ATOM   7165 O OD2  . ASP C 3 171 ? -6.183  13.645 32.684  1.00 25.21 ? 171 ASP L OD2  1 
ATOM   7166 H H    . ASP C 3 171 ? -2.260  14.296 32.008  1.00 25.11 ? 171 ASP L H    1 
ATOM   7167 H HA   . ASP C 3 171 ? -2.289  11.656 32.742  1.00 19.40 ? 171 ASP L HA   1 
ATOM   7168 H HB2  . ASP C 3 171 ? -4.471  11.745 33.172  1.00 26.81 ? 171 ASP L HB2  1 
ATOM   7169 H HB3  . ASP C 3 171 ? -3.956  13.120 33.780  1.00 26.81 ? 171 ASP L HB3  1 
ATOM   7170 N N    . SER C 3 172 ? -2.134  12.593 29.910  1.00 17.35 ? 172 SER L N    1 
ATOM   7171 C CA   . SER C 3 172 ? -2.070  12.180 28.501  1.00 15.81 ? 172 SER L CA   1 
ATOM   7172 C C    . SER C 3 172 ? -3.444  12.044 27.838  1.00 15.43 ? 172 SER L C    1 
ATOM   7173 O O    . SER C 3 172 ? -3.570  11.355 26.818  1.00 13.56 ? 172 SER L O    1 
ATOM   7174 C CB   . SER C 3 172 ? -1.286  10.871 28.331  1.00 18.93 ? 172 SER L CB   1 
ATOM   7175 O OG   . SER C 3 172 ? -0.034  10.968 28.962  1.00 19.43 ? 172 SER L OG   1 
ATOM   7176 H H    . SER C 3 172 ? -1.682  13.307 30.073  1.00 20.88 ? 172 SER L H    1 
ATOM   7177 H HA   . SER C 3 172 ? -1.601  12.888 28.032  1.00 19.04 ? 172 SER L HA   1 
ATOM   7178 H HB2  . SER C 3 172 ? -1.789  10.145 28.733  1.00 22.77 ? 172 SER L HB2  1 
ATOM   7179 H HB3  . SER C 3 172 ? -1.154  10.700 27.386  1.00 22.77 ? 172 SER L HB3  1 
ATOM   7180 H HG   . SER C 3 172 ? 0.267   10.201 29.123  1.00 23.37 ? 172 SER L HG   1 
ATOM   7181 N N    . THR C 3 173 ? -4.484  12.699 28.342  1.00 12.77 ? 173 THR L N    1 
ATOM   7182 C CA   . THR C 3 173 ? -5.768  12.716 27.657  1.00 13.06 ? 173 THR L CA   1 
ATOM   7183 C C    . THR C 3 173 ? -5.915  13.951 26.745  1.00 12.14 ? 173 THR L C    1 
ATOM   7184 O O    . THR C 3 173 ? -5.137  14.919 26.785  1.00 14.20 ? 173 THR L O    1 
ATOM   7185 C CB   . THR C 3 173 ? -6.949  12.720 28.657  1.00 14.52 ? 173 THR L CB   1 
ATOM   7186 O OG1  . THR C 3 173 ? -6.906  13.949 29.406  1.00 14.15 ? 173 THR L OG1  1 
ATOM   7187 C CG2  . THR C 3 173 ? -6.882  11.522 29.605  1.00 15.40 ? 173 THR L CG2  1 
ATOM   7188 H H    . THR C 3 173 ? -4.469  13.141 29.079  1.00 15.39 ? 173 THR L H    1 
ATOM   7189 H HA   . THR C 3 173 ? -5.804  11.911 27.118  1.00 15.73 ? 173 THR L HA   1 
ATOM   7190 H HB   . THR C 3 173 ? -7.789  12.652 28.178  1.00 17.48 ? 173 THR L HB   1 
ATOM   7191 H HG1  . THR C 3 173 ? -6.172  14.015 29.809  1.00 17.05 ? 173 THR L HG1  1 
ATOM   7192 H HG21 . THR C 3 173 ? -7.663  11.509 30.179  1.00 18.54 ? 173 THR L HG21 1 
ATOM   7193 H HG22 . THR C 3 173 ? -6.853  10.697 29.095  1.00 18.54 ? 173 THR L HG22 1 
ATOM   7194 H HG23 . THR C 3 173 ? -6.086  11.579 30.156  1.00 18.54 ? 173 THR L HG23 1 
ATOM   7195 N N    . TYR C 3 174 ? -7.007  13.945 25.991  1.00 13.09 ? 174 TYR L N    1 
ATOM   7196 C CA   . TYR C 3 174 ? -7.451  15.045 25.165  1.00 15.40 ? 174 TYR L CA   1 
ATOM   7197 C C    . TYR C 3 174 ? -8.766  15.566 25.720  1.00 14.91 ? 174 TYR L C    1 
ATOM   7198 O O    . TYR C 3 174 ? -9.519  14.846 26.376  1.00 13.63 ? 174 TYR L O    1 
ATOM   7199 C CB   . TYR C 3 174 ? -7.653  14.622 23.704  1.00 14.13 ? 174 TYR L CB   1 
ATOM   7200 C CG   . TYR C 3 174 ? -6.372  14.168 23.061  1.00 15.79 ? 174 TYR L CG   1 
ATOM   7201 C CD1  . TYR C 3 174 ? -5.954  12.848 23.135  1.00 16.81 ? 174 TYR L CD1  1 
ATOM   7202 C CD2  . TYR C 3 174 ? -5.545  15.087 22.430  1.00 16.68 ? 174 TYR L CD2  1 
ATOM   7203 C CE1  . TYR C 3 174 ? -4.745  12.463 22.526  1.00 15.01 ? 174 TYR L CE1  1 
ATOM   7204 C CE2  . TYR C 3 174 ? -4.332  14.719 21.867  1.00 17.53 ? 174 TYR L CE2  1 
ATOM   7205 C CZ   . TYR C 3 174 ? -3.935  13.421 21.922  1.00 15.58 ? 174 TYR L CZ   1 
ATOM   7206 O OH   . TYR C 3 174 ? -2.740  13.094 21.339  1.00 21.99 ? 174 TYR L OH   1 
ATOM   7207 H H    . TYR C 3 174 ? -7.537  13.269 25.942  1.00 15.77 ? 174 TYR L H    1 
ATOM   7208 H HA   . TYR C 3 174 ? -6.782  15.746 25.174  1.00 18.54 ? 174 TYR L HA   1 
ATOM   7209 H HB2  . TYR C 3 174 ? -8.285  13.888 23.670  1.00 17.02 ? 174 TYR L HB2  1 
ATOM   7210 H HB3  . TYR C 3 174 ? -7.994  15.377 23.199  1.00 17.02 ? 174 TYR L HB3  1 
ATOM   7211 H HD1  . TYR C 3 174 ? -6.470  12.219 23.586  1.00 20.24 ? 174 TYR L HD1  1 
ATOM   7212 H HD2  . TYR C 3 174 ? -5.812  15.976 22.383  1.00 20.08 ? 174 TYR L HD2  1 
ATOM   7213 H HE1  . TYR C 3 174 ? -4.487  11.570 22.528  1.00 18.08 ? 174 TYR L HE1  1 
ATOM   7214 H HE2  . TYR C 3 174 ? -3.794  15.357 21.456  1.00 21.09 ? 174 TYR L HE2  1 
ATOM   7215 H HH   . TYR C 3 174 ? -2.612  12.266 21.391  1.00 26.45 ? 174 TYR L HH   1 
ATOM   7216 N N    . SER C 3 175 ? -9.052  16.831 25.430  1.00 12.59 ? 175 SER L N    1 
ATOM   7217 C CA   . SER C 3 175 ? -10.381 17.373 25.624  1.00 13.33 ? 175 SER L CA   1 
ATOM   7218 C C    . SER C 3 175 ? -10.785 18.062 24.328  1.00 12.88 ? 175 SER L C    1 
ATOM   7219 O O    . SER C 3 175 ? -9.931  18.511 23.552  1.00 15.19 ? 175 SER L O    1 
ATOM   7220 C CB   . SER C 3 175 ? -10.358 18.340 26.784  1.00 14.39 ? 175 SER L CB   1 
ATOM   7221 O OG   . SER C 3 175 ? -10.283 17.620 28.003  1.00 16.34 ? 175 SER L OG   1 
ATOM   7222 H H    . SER C 3 175 ? -8.484  17.396 25.117  1.00 15.17 ? 175 SER L H    1 
ATOM   7223 H HA   . SER C 3 175 ? -11.045 16.693 25.817  1.00 16.05 ? 175 SER L HA   1 
ATOM   7224 H HB2  . SER C 3 175 ? -9.583  18.918 26.705  1.00 17.33 ? 175 SER L HB2  1 
ATOM   7225 H HB3  . SER C 3 175 ? -11.170 18.871 26.775  1.00 17.33 ? 175 SER L HB3  1 
ATOM   7226 H HG   . SER C 3 175 ? -9.518  17.286 28.093  1.00 19.67 ? 175 SER L HG   1 
ATOM   7227 N N    . LEU C 3 176 ? -12.073 18.162 24.078  1.00 12.23 ? 176 LEU L N    1 
ATOM   7228 C CA   . LEU C 3 176 ? -12.599 18.638 22.807  1.00 15.16 ? 176 LEU L CA   1 
ATOM   7229 C C    . LEU C 3 176 ? -13.853 19.444 23.068  1.00 16.08 ? 176 LEU L C    1 
ATOM   7230 O O    . LEU C 3 176 ? -14.676 19.069 23.914  1.00 16.04 ? 176 LEU L O    1 
ATOM   7231 C CB   . LEU C 3 176 ? -12.992 17.477 21.903  1.00 17.43 ? 176 LEU L CB   1 
ATOM   7232 C CG   . LEU C 3 176 ? -13.510 17.783 20.517  1.00 19.23 ? 176 LEU L CG   1 
ATOM   7233 C CD1  . LEU C 3 176 ? -12.888 16.920 19.382  1.00 25.75 ? 176 LEU L CD1  1 
ATOM   7234 C CD2  . LEU C 3 176 ? -14.984 17.635 20.578  1.00 19.88 ? 176 LEU L CD2  1 
ATOM   7235 H H    . LEU C 3 176 ? -12.686 17.954 24.644  1.00 14.74 ? 176 LEU L H    1 
ATOM   7236 H HA   . LEU C 3 176 ? -11.927 19.187 22.373  1.00 18.25 ? 176 LEU L HA   1 
ATOM   7237 H HB2  . LEU C 3 176 ? -12.207 16.918 21.787  1.00 20.98 ? 176 LEU L HB2  1 
ATOM   7238 H HB3  . LEU C 3 176 ? -13.690 16.978 22.355  1.00 20.98 ? 176 LEU L HB3  1 
ATOM   7239 H HG   . LEU C 3 176 ? -13.251 18.683 20.267  1.00 23.14 ? 176 LEU L HG   1 
ATOM   7240 H HD11 . LEU C 3 176 ? -13.184 17.264 18.525  1.00 30.97 ? 176 LEU L HD11 1 
ATOM   7241 H HD12 . LEU C 3 176 ? -11.921 16.969 19.443  1.00 30.97 ? 176 LEU L HD12 1 
ATOM   7242 H HD13 . LEU C 3 176 ? -13.179 16.001 19.488  1.00 30.97 ? 176 LEU L HD13 1 
ATOM   7243 H HD21 . LEU C 3 176 ? -15.378 18.078 19.810  1.00 23.92 ? 176 LEU L HD21 1 
ATOM   7244 H HD22 . LEU C 3 176 ? -15.208 16.691 20.565  1.00 23.92 ? 176 LEU L HD22 1 
ATOM   7245 H HD23 . LEU C 3 176 ? -15.309 18.041 21.397  1.00 23.92 ? 176 LEU L HD23 1 
ATOM   7246 N N    . SER C 3 177 ? -13.967 20.572 22.387  1.00 13.46 ? 177 SER L N    1 
ATOM   7247 C CA   . SER C 3 177 ? -15.222 21.304 22.302  1.00 16.97 ? 177 SER L CA   1 
ATOM   7248 C C    . SER C 3 177 ? -15.829 21.217 20.905  1.00 22.22 ? 177 SER L C    1 
ATOM   7249 O O    . SER C 3 177 ? -15.117 21.258 19.893  1.00 20.02 ? 177 SER L O    1 
ATOM   7250 C CB   . SER C 3 177 ? -14.994 22.764 22.655  1.00 18.93 ? 177 SER L CB   1 
ATOM   7251 O OG   . SER C 3 177 ? -14.313 23.404 21.585  1.00 19.54 ? 177 SER L OG   1 
ATOM   7252 H H    . SER C 3 177 ? -13.320 20.942 21.958  1.00 16.21 ? 177 SER L H    1 
ATOM   7253 H HA   . SER C 3 177 ? -15.857 20.906 22.917  1.00 20.42 ? 177 SER L HA   1 
ATOM   7254 H HB2  . SER C 3 177 ? -15.850 23.197 22.797  1.00 22.78 ? 177 SER L HB2  1 
ATOM   7255 H HB3  . SER C 3 177 ? -14.456 22.820 23.460  1.00 22.78 ? 177 SER L HB3  1 
ATOM   7256 H HG   . SER C 3 177 ? -13.907 24.082 21.869  1.00 23.51 ? 177 SER L HG   1 
ATOM   7257 N N    . SER C 3 178 ? -17.161 21.125 20.861  1.00 20.91 ? 178 SER L N    1 
ATOM   7258 C CA   . SER C 3 178 ? -17.957 21.371 19.666  1.00 18.59 ? 178 SER L CA   1 
ATOM   7259 C C    . SER C 3 178 ? -18.914 22.525 19.921  1.00 19.17 ? 178 SER L C    1 
ATOM   7260 O O    . SER C 3 178 ? -19.622 22.525 20.916  1.00 21.54 ? 178 SER L O    1 
ATOM   7261 C CB   . SER C 3 178 ? -18.751 20.147 19.242  1.00 24.77 ? 178 SER L CB   1 
ATOM   7262 O OG   . SER C 3 178 ? -19.138 20.245 17.884  1.00 29.54 ? 178 SER L OG   1 
ATOM   7263 H H    . SER C 3 178 ? -17.641 20.913 21.542  1.00 25.15 ? 178 SER L H    1 
ATOM   7264 H HA   . SER C 3 178 ? -17.355 21.608 18.943  1.00 22.37 ? 178 SER L HA   1 
ATOM   7265 H HB2  . SER C 3 178 ? -18.199 19.357 19.357  1.00 29.78 ? 178 SER L HB2  1 
ATOM   7266 H HB3  . SER C 3 178 ? -19.546 20.079 19.794  1.00 29.78 ? 178 SER L HB3  1 
ATOM   7267 H HG   . SER C 3 178 ? -19.566 19.559 17.656  1.00 35.51 ? 178 SER L HG   1 
ATOM   7268 N N    . THR C 3 179 ? -18.895 23.508 19.035  1.00 19.48 ? 179 THR L N    1 
ATOM   7269 C CA   . THR C 3 179 ? -19.708 24.708 19.163  1.00 22.52 ? 179 THR L CA   1 
ATOM   7270 C C    . THR C 3 179 ? -20.641 24.785 17.970  1.00 23.49 ? 179 THR L C    1 
ATOM   7271 O O    . THR C 3 179 ? -20.180 24.915 16.832  1.00 21.36 ? 179 THR L O    1 
ATOM   7272 C CB   . THR C 3 179 ? -18.834 25.953 19.262  1.00 21.17 ? 179 THR L CB   1 
ATOM   7273 O OG1  . THR C 3 179 ? -17.878 25.773 20.319  1.00 22.22 ? 179 THR L OG1  1 
ATOM   7274 C CG2  . THR C 3 179 ? -19.700 27.209 19.521  1.00 23.90 ? 179 THR L CG2  1 
ATOM   7275 H H    . THR C 3 179 ? -18.405 23.503 18.329  1.00 23.44 ? 179 THR L H    1 
ATOM   7276 H HA   . THR C 3 179 ? -20.248 24.659 19.967  1.00 27.09 ? 179 THR L HA   1 
ATOM   7277 H HB   . THR C 3 179 ? -18.360 26.096 18.428  1.00 25.46 ? 179 THR L HB   1 
ATOM   7278 H HG1  . THR C 3 179 ? -17.404 26.462 20.399  1.00 26.72 ? 179 THR L HG1  1 
ATOM   7279 H HG21 . THR C 3 179 ? -19.133 27.992 19.603  1.00 28.74 ? 179 THR L HG21 1 
ATOM   7280 H HG22 . THR C 3 179 ? -20.317 27.344 18.785  1.00 28.74 ? 179 THR L HG22 1 
ATOM   7281 H HG23 . THR C 3 179 ? -20.206 27.100 20.341  1.00 28.74 ? 179 THR L HG23 1 
ATOM   7282 N N    . LEU C 3 180 ? -21.938 24.755 18.262  1.00 23.76 ? 180 LEU L N    1 
ATOM   7283 C CA   . LEU C 3 180 ? -23.008 24.963 17.296  1.00 25.29 ? 180 LEU L CA   1 
ATOM   7284 C C    . LEU C 3 180 ? -23.437 26.419 17.338  1.00 25.09 ? 180 LEU L C    1 
ATOM   7285 O O    . LEU C 3 180 ? -23.793 26.931 18.406  1.00 26.54 ? 180 LEU L O    1 
ATOM   7286 C CB   . LEU C 3 180 ? -24.196 24.076 17.647  1.00 26.47 ? 180 LEU L CB   1 
ATOM   7287 C CG   . LEU C 3 180 ? -25.408 24.140 16.731  1.00 27.33 ? 180 LEU L CG   1 
ATOM   7288 C CD1  . LEU C 3 180 ? -25.251 23.217 15.551  1.00 34.41 ? 180 LEU L CD1  1 
ATOM   7289 C CD2  . LEU C 3 180 ? -26.614 23.751 17.559  1.00 26.66 ? 180 LEU L CD2  1 
ATOM   7290 H H    . LEU C 3 180 ? -22.238 24.609 19.054  1.00 28.57 ? 180 LEU L H    1 
ATOM   7291 H HA   . LEU C 3 180 ? -22.691 24.749 16.404  1.00 30.41 ? 180 LEU L HA   1 
ATOM   7292 H HB2  . LEU C 3 180 ? -23.890 23.156 17.645  1.00 31.83 ? 180 LEU L HB2  1 
ATOM   7293 H HB3  . LEU C 3 180 ? -24.500 24.323 18.534  1.00 31.83 ? 180 LEU L HB3  1 
ATOM   7294 H HG   . LEU C 3 180 ? -25.519 25.032 16.368  1.00 32.86 ? 180 LEU L HG   1 
ATOM   7295 H HD11 . LEU C 3 180 ? -26.065 23.237 15.024  1.00 41.36 ? 180 LEU L HD11 1 
ATOM   7296 H HD12 . LEU C 3 180 ? -24.502 23.516 15.014  1.00 41.36 ? 180 LEU L HD12 1 
ATOM   7297 H HD13 . LEU C 3 180 ? -25.088 22.317 15.874  1.00 41.36 ? 180 LEU L HD13 1 
ATOM   7298 H HD21 . LEU C 3 180 ? -27.391 23.700 16.980  1.00 32.06 ? 180 LEU L HD21 1 
ATOM   7299 H HD22 . LEU C 3 180 ? -26.451 22.888 17.970  1.00 32.06 ? 180 LEU L HD22 1 
ATOM   7300 H HD23 . LEU C 3 180 ? -26.756 24.423 18.244  1.00 32.06 ? 180 LEU L HD23 1 
ATOM   7301 N N    . THR C 3 181 ? -23.401 27.089 16.197  1.00 24.86 ? 181 THR L N    1 
ATOM   7302 C CA   . THR C 3 181 ? -23.769 28.498 16.133  1.00 26.60 ? 181 THR L CA   1 
ATOM   7303 C C    . THR C 3 181 ? -25.038 28.664 15.315  1.00 34.09 ? 181 THR L C    1 
ATOM   7304 O O    . THR C 3 181 ? -25.062 28.345 14.127  1.00 35.02 ? 181 THR L O    1 
ATOM   7305 C CB   . THR C 3 181 ? -22.644 29.354 15.562  1.00 33.16 ? 181 THR L CB   1 
ATOM   7306 O OG1  . THR C 3 181 ? -21.419 29.098 16.271  1.00 27.74 ? 181 THR L OG1  1 
ATOM   7307 C CG2  . THR C 3 181 ? -23.006 30.815 15.655  1.00 29.94 ? 181 THR L CG2  1 
ATOM   7308 H H    . THR C 3 181 ? -23.166 26.749 15.442  1.00 29.89 ? 181 THR L H    1 
ATOM   7309 H HA   . THR C 3 181 ? -23.952 28.804 17.035  1.00 31.98 ? 181 THR L HA   1 
ATOM   7310 H HB   . THR C 3 181 ? -22.506 29.135 14.628  1.00 39.85 ? 181 THR L HB   1 
ATOM   7311 H HG1  . THR C 3 181 ? -21.583 28.927 17.077  1.00 33.35 ? 181 THR L HG1  1 
ATOM   7312 H HG21 . THR C 3 181 ? -22.204 31.349 15.767  1.00 35.98 ? 181 THR L HG21 1 
ATOM   7313 H HG22 . THR C 3 181 ? -23.460 31.096 14.845  1.00 35.98 ? 181 THR L HG22 1 
ATOM   7314 H HG23 . THR C 3 181 ? -23.592 30.964 16.413  1.00 35.98 ? 181 THR L HG23 1 
ATOM   7315 N N    . LEU C 3 182 ? -26.082 29.167 15.968  1.00 28.41 ? 182 LEU L N    1 
ATOM   7316 C CA   . LEU C 3 182 ? -27.356 29.466 15.330  1.00 34.83 ? 182 LEU L CA   1 
ATOM   7317 C C    . LEU C 3 182 ? -27.685 30.941 15.501  1.00 32.76 ? 182 LEU L C    1 
ATOM   7318 O O    . LEU C 3 182 ? -27.176 31.608 16.405  1.00 30.33 ? 182 LEU L O    1 
ATOM   7319 C CB   . LEU C 3 182 ? -28.487 28.619 15.920  1.00 31.31 ? 182 LEU L CB   1 
ATOM   7320 C CG   . LEU C 3 182 ? -28.218 27.139 16.086  1.00 33.40 ? 182 LEU L CG   1 
ATOM   7321 C CD1  . LEU C 3 182 ? -29.428 26.453 16.643  1.00 38.54 ? 182 LEU L CD1  1 
ATOM   7322 C CD2  . LEU C 3 182 ? -27.830 26.571 14.727  1.00 34.42 ? 182 LEU L CD2  1 
ATOM   7323 H H    . LEU C 3 182 ? -26.074 29.349 16.809  1.00 34.15 ? 182 LEU L H    1 
ATOM   7324 H HA   . LEU C 3 182 ? -27.290 29.272 14.382  1.00 41.86 ? 182 LEU L HA   1 
ATOM   7325 H HB2  . LEU C 3 182 ? -28.695 28.969 16.801  1.00 37.63 ? 182 LEU L HB2  1 
ATOM   7326 H HB3  . LEU C 3 182 ? -29.259 28.703 15.339  1.00 37.63 ? 182 LEU L HB3  1 
ATOM   7327 H HG   . LEU C 3 182 ? -27.492 26.983 16.710  1.00 40.14 ? 182 LEU L HG   1 
ATOM   7328 H HD11 . LEU C 3 182 ? -29.236 25.508 16.746  1.00 46.31 ? 182 LEU L HD11 1 
ATOM   7329 H HD12 . LEU C 3 182 ? -29.643 26.843 17.505  1.00 46.31 ? 182 LEU L HD12 1 
ATOM   7330 H HD13 . LEU C 3 182 ? -30.170 26.575 16.030  1.00 46.31 ? 182 LEU L HD13 1 
ATOM   7331 H HD21 . LEU C 3 182 ? -27.650 25.623 14.821  1.00 41.37 ? 182 LEU L HD21 1 
ATOM   7332 H HD22 . LEU C 3 182 ? -28.562 26.709 14.106  1.00 41.37 ? 182 LEU L HD22 1 
ATOM   7333 H HD23 . LEU C 3 182 ? -27.036 27.029 14.408  1.00 41.37 ? 182 LEU L HD23 1 
ATOM   7334 N N    . SER C 3 183 ? -28.573 31.452 14.645  1.00 40.89 ? 183 SER L N    1 
ATOM   7335 C CA   . SER C 3 183 ? -29.149 32.761 14.923  1.00 34.95 ? 183 SER L CA   1 
ATOM   7336 C C    . SER C 3 183 ? -30.073 32.634 16.125  1.00 22.77 ? 183 SER L C    1 
ATOM   7337 O O    . SER C 3 183 ? -30.600 31.552 16.421  1.00 32.45 ? 183 SER L O    1 
ATOM   7338 C CB   . SER C 3 183 ? -29.952 33.284 13.732  1.00 35.83 ? 183 SER L CB   1 
ATOM   7339 O OG   . SER C 3 183 ? -31.037 32.409 13.465  1.00 38.49 ? 183 SER L OG   1 
ATOM   7340 H H    . SER C 3 183 ? -28.847 31.072 13.924  1.00 49.13 ? 183 SER L H    1 
ATOM   7341 H HA   . SER C 3 183 ? -28.441 33.400 15.099  1.00 42.01 ? 183 SER L HA   1 
ATOM   7342 H HB2  . SER C 3 183 ? -30.296 34.166 13.940  1.00 43.06 ? 183 SER L HB2  1 
ATOM   7343 H HB3  . SER C 3 183 ? -29.377 33.327 12.952  1.00 43.06 ? 183 SER L HB3  1 
ATOM   7344 H HG   . SER C 3 183 ? -31.747 32.850 13.380  1.00 46.25 ? 183 SER L HG   1 
ATOM   7345 N N    . LYS C 3 184 ? -30.304 33.759 16.808  1.00 33.41 ? 184 LYS L N    1 
ATOM   7346 C CA   . LYS C 3 184 ? -31.297 33.728 17.873  1.00 37.05 ? 184 LYS L CA   1 
ATOM   7347 C C    . LYS C 3 184 ? -32.650 33.333 17.309  1.00 32.83 ? 184 LYS L C    1 
ATOM   7348 O O    . LYS C 3 184 ? -33.375 32.535 17.906  1.00 32.63 ? 184 LYS L O    1 
ATOM   7349 C CB   . LYS C 3 184 ? -31.420 35.075 18.555  1.00 37.09 ? 184 LYS L CB   1 
ATOM   7350 C CG   . LYS C 3 184 ? -32.625 35.124 19.484  1.00 38.60 ? 184 LYS L CG   1 
ATOM   7351 C CD   . LYS C 3 184 ? -32.515 36.227 20.520  1.00 44.03 ? 184 LYS L CD   1 
ATOM   7352 C CE   . LYS C 3 184 ? -33.736 37.101 20.521  1.00 41.70 ? 184 LYS L CE   1 
ATOM   7353 N NZ   . LYS C 3 184 ? -33.533 38.212 21.482  1.00 44.55 ? 184 LYS L NZ   1 
ATOM   7354 H H    . LYS C 3 184 ? -29.915 34.515 16.678  1.00 40.15 ? 184 LYS L H    1 
ATOM   7355 H HA   . LYS C 3 184 ? -31.008 33.084 18.538  1.00 44.52 ? 184 LYS L HA   1 
ATOM   7356 H HB2  . LYS C 3 184 ? -30.622 35.241 19.081  1.00 44.57 ? 184 LYS L HB2  1 
ATOM   7357 H HB3  . LYS C 3 184 ? -31.524 35.766 17.883  1.00 44.57 ? 184 LYS L HB3  1 
ATOM   7358 H HG2  . LYS C 3 184 ? -33.424 35.283 18.959  1.00 46.38 ? 184 LYS L HG2  1 
ATOM   7359 H HG3  . LYS C 3 184 ? -32.698 34.278 19.953  1.00 46.38 ? 184 LYS L HG3  1 
ATOM   7360 H HD2  . LYS C 3 184 ? -32.421 35.833 21.401  1.00 52.90 ? 184 LYS L HD2  1 
ATOM   7361 H HD3  . LYS C 3 184 ? -31.744 36.781 20.320  1.00 52.90 ? 184 LYS L HD3  1 
ATOM   7362 H HE2  . LYS C 3 184 ? -33.879 37.471 19.636  1.00 50.11 ? 184 LYS L HE2  1 
ATOM   7363 H HE3  . LYS C 3 184 ? -34.511 36.586 20.795  1.00 50.11 ? 184 LYS L HE3  1 
ATOM   7364 H HZ1  . LYS C 3 184 ? -34.253 38.735 21.501  1.00 53.52 ? 184 LYS L HZ1  1 
ATOM   7365 H HZ2  . LYS C 3 184 ? -33.391 37.887 22.298  1.00 53.52 ? 184 LYS L HZ2  1 
ATOM   7366 H HZ3  . LYS C 3 184 ? -32.829 38.700 21.239  1.00 53.52 ? 184 LYS L HZ3  1 
ATOM   7367 N N    . ALA C 3 185 ? -32.999 33.883 16.144  1.00 39.99 ? 185 ALA L N    1 
ATOM   7368 C CA   . ALA C 3 185 ? -34.256 33.521 15.499  1.00 37.07 ? 185 ALA L CA   1 
ATOM   7369 C C    . ALA C 3 185 ? -34.404 32.008 15.409  1.00 40.30 ? 185 ALA L C    1 
ATOM   7370 O O    . ALA C 3 185 ? -35.423 31.445 15.824  1.00 43.42 ? 185 ALA L O    1 
ATOM   7371 C CB   . ALA C 3 185 ? -34.333 34.156 14.102  1.00 38.84 ? 185 ALA L CB   1 
ATOM   7372 H H    . ALA C 3 185 ? -32.531 34.462 15.714  1.00 48.05 ? 185 ALA L H    1 
ATOM   7373 H HA   . ALA C 3 185 ? -34.992 33.868 16.027  1.00 44.55 ? 185 ALA L HA   1 
ATOM   7374 H HB1  . ALA C 3 185 ? -35.187 33.932 13.701  1.00 46.66 ? 185 ALA L HB1  1 
ATOM   7375 H HB2  . ALA C 3 185 ? -34.250 35.119 14.188  1.00 46.66 ? 185 ALA L HB2  1 
ATOM   7376 H HB3  . ALA C 3 185 ? -33.610 33.809 13.557  1.00 46.66 ? 185 ALA L HB3  1 
ATOM   7377 N N    . ASP C 3 186 ? -33.377 31.326 14.905  1.00 38.88 ? 186 ASP L N    1 
ATOM   7378 C CA   . ASP C 3 186 ? -33.464 29.879 14.782  1.00 40.60 ? 186 ASP L CA   1 
ATOM   7379 C C    . ASP C 3 186 ? -33.359 29.182 16.127  1.00 37.69 ? 186 ASP L C    1 
ATOM   7380 O O    . ASP C 3 186 ? -34.026 28.163 16.343  1.00 40.20 ? 186 ASP L O    1 
ATOM   7381 C CB   . ASP C 3 186 ? -32.377 29.370 13.850  1.00 40.95 ? 186 ASP L CB   1 
ATOM   7382 C CG   . ASP C 3 186 ? -32.773 29.450 12.394  1.00 48.64 ? 186 ASP L CG   1 
ATOM   7383 O OD1  . ASP C 3 186 ? -32.814 30.573 11.840  1.00 54.15 ? 186 ASP L OD1  1 
ATOM   7384 O OD2  . ASP C 3 186 ? -33.030 28.375 11.802  1.00 54.65 ? 186 ASP L OD2  1 
ATOM   7385 H H    . ASP C 3 186 ? -32.637 31.671 14.635  1.00 46.71 ? 186 ASP L H    1 
ATOM   7386 H HA   . ASP C 3 186 ? -34.330 29.662 14.401  1.00 48.79 ? 186 ASP L HA   1 
ATOM   7387 H HB2  . ASP C 3 186 ? -31.578 29.906 13.973  1.00 49.20 ? 186 ASP L HB2  1 
ATOM   7388 H HB3  . ASP C 3 186 ? -32.189 28.442 14.059  1.00 49.20 ? 186 ASP L HB3  1 
ATOM   7389 N N    . TYR C 3 187 ? -32.538 29.706 17.044  1.00 34.86 ? 187 TYR L N    1 
ATOM   7390 C CA   . TYR C 3 187 ? -32.472 29.111 18.372  1.00 36.70 ? 187 TYR L CA   1 
ATOM   7391 C C    . TYR C 3 187 ? -33.845 29.093 19.017  1.00 39.79 ? 187 TYR L C    1 
ATOM   7392 O O    . TYR C 3 187 ? -34.257 28.077 19.600  1.00 33.32 ? 187 TYR L O    1 
ATOM   7393 C CB   . TYR C 3 187 ? -31.481 29.869 19.260  1.00 33.31 ? 187 TYR L CB   1 
ATOM   7394 C CG   . TYR C 3 187 ? -31.373 29.283 20.648  1.00 30.86 ? 187 TYR L CG   1 
ATOM   7395 C CD1  . TYR C 3 187 ? -30.875 28.004 20.847  1.00 29.19 ? 187 TYR L CD1  1 
ATOM   7396 C CD2  . TYR C 3 187 ? -31.769 30.000 21.770  1.00 31.26 ? 187 TYR L CD2  1 
ATOM   7397 C CE1  . TYR C 3 187 ? -30.796 27.445 22.121  1.00 29.86 ? 187 TYR L CE1  1 
ATOM   7398 C CE2  . TYR C 3 187 ? -31.671 29.448 23.036  1.00 31.06 ? 187 TYR L CE2  1 
ATOM   7399 C CZ   . TYR C 3 187 ? -31.175 28.173 23.191  1.00 29.73 ? 187 TYR L CZ   1 
ATOM   7400 O OH   . TYR C 3 187 ? -31.059 27.601 24.417  1.00 29.91 ? 187 TYR L OH   1 
ATOM   7401 H H    . TYR C 3 187 ? -32.026 30.386 16.922  1.00 41.89 ? 187 TYR L H    1 
ATOM   7402 H HA   . TYR C 3 187 ? -32.150 28.200 18.288  1.00 44.10 ? 187 TYR L HA   1 
ATOM   7403 H HB2  . TYR C 3 187 ? -30.602 29.837 18.851  1.00 40.03 ? 187 TYR L HB2  1 
ATOM   7404 H HB3  . TYR C 3 187 ? -31.774 30.790 19.345  1.00 40.03 ? 187 TYR L HB3  1 
ATOM   7405 H HD1  . TYR C 3 187 ? -30.588 27.508 20.114  1.00 35.09 ? 187 TYR L HD1  1 
ATOM   7406 H HD2  . TYR C 3 187 ? -32.104 30.862 21.670  1.00 37.57 ? 187 TYR L HD2  1 
ATOM   7407 H HE1  . TYR C 3 187 ? -30.485 26.576 22.232  1.00 35.90 ? 187 TYR L HE1  1 
ATOM   7408 H HE2  . TYR C 3 187 ? -31.940 29.937 23.779  1.00 37.33 ? 187 TYR L HE2  1 
ATOM   7409 H HH   . TYR C 3 187 ? -31.281 28.151 25.012  1.00 35.95 ? 187 TYR L HH   1 
ATOM   7410 N N    . GLU C 3 188 ? -34.588 30.200 18.878  1.00 41.48 ? 188 GLU L N    1 
ATOM   7411 C CA   . GLU C 3 188 ? -35.889 30.321 19.532  1.00 40.32 ? 188 GLU L CA   1 
ATOM   7412 C C    . GLU C 3 188 ? -36.929 29.435 18.860  1.00 40.85 ? 188 GLU L C    1 
ATOM   7413 O O    . GLU C 3 188 ? -37.916 29.060 19.496  1.00 46.51 ? 188 GLU L O    1 
ATOM   7414 C CB   . GLU C 3 188 ? -36.328 31.795 19.541  1.00 39.81 ? 188 GLU L CB   1 
ATOM   7415 C CG   . GLU C 3 188 ? -35.275 32.725 20.117  1.00 42.15 ? 188 GLU L CG   1 
ATOM   7416 C CD   . GLU C 3 188 ? -35.844 33.799 21.003  1.00 41.87 ? 188 GLU L CD   1 
ATOM   7417 O OE1  . GLU C 3 188 ? -36.861 34.416 20.600  1.00 47.97 ? 188 GLU L OE1  1 
ATOM   7418 O OE2  . GLU C 3 188 ? -35.264 34.038 22.088  1.00 46.35 ? 188 GLU L OE2  1 
ATOM   7419 H H    . GLU C 3 188 ? -34.360 30.888 18.413  1.00 49.84 ? 188 GLU L H    1 
ATOM   7420 H HA   . GLU C 3 188 ? -35.826 30.041 20.458  1.00 48.44 ? 188 GLU L HA   1 
ATOM   7421 H HB2  . GLU C 3 188 ? -36.509 32.075 18.630  1.00 47.83 ? 188 GLU L HB2  1 
ATOM   7422 H HB3  . GLU C 3 188 ? -37.130 31.880 20.080  1.00 47.83 ? 188 GLU L HB3  1 
ATOM   7423 H HG2  . GLU C 3 188 ? -34.651 32.204 20.645  1.00 50.64 ? 188 GLU L HG2  1 
ATOM   7424 H HG3  . GLU C 3 188 ? -34.808 33.160 19.386  1.00 50.64 ? 188 GLU L HG3  1 
ATOM   7425 N N    . LYS C 3 189 ? -36.725 29.089 17.589  1.00 41.59 ? 189 LYS L N    1 
ATOM   7426 C CA   . LYS C 3 189 ? -37.663 28.194 16.919  1.00 40.63 ? 189 LYS L CA   1 
ATOM   7427 C C    . LYS C 3 189 ? -37.748 26.824 17.588  1.00 48.38 ? 189 LYS L C    1 
ATOM   7428 O O    . LYS C 3 189 ? -38.844 26.262 17.715  1.00 50.01 ? 189 LYS L O    1 
ATOM   7429 C CB   . LYS C 3 189 ? -37.266 28.017 15.463  1.00 41.11 ? 189 LYS L CB   1 
ATOM   7430 C CG   . LYS C 3 189 ? -37.945 28.963 14.504  1.00 45.45 ? 189 LYS L CG   1 
ATOM   7431 C CD   . LYS C 3 189 ? -39.366 28.472 14.153  1.00 60.62 ? 189 LYS L CD   1 
ATOM   7432 C CE   . LYS C 3 189 ? -39.382 27.111 13.457  1.00 63.56 ? 189 LYS L CE   1 
ATOM   7433 N NZ   . LYS C 3 189 ? -39.224 27.219 11.981  1.00 61.70 ? 189 LYS L NZ   1 
ATOM   7434 H H    . LYS C 3 189 ? -36.066 29.353 17.104  1.00 49.97 ? 189 LYS L H    1 
ATOM   7435 H HA   . LYS C 3 189 ? -38.540 28.606 16.967  1.00 48.82 ? 189 LYS L HA   1 
ATOM   7436 H HB2  . LYS C 3 189 ? -36.310 28.159 15.385  1.00 49.39 ? 189 LYS L HB2  1 
ATOM   7437 H HB3  . LYS C 3 189 ? -37.491 27.114 15.190  1.00 49.39 ? 189 LYS L HB3  1 
ATOM   7438 H HG2  . LYS C 3 189 ? -38.016 29.841 14.912  1.00 54.61 ? 189 LYS L HG2  1 
ATOM   7439 H HG3  . LYS C 3 189 ? -37.428 29.019 13.685  1.00 54.61 ? 189 LYS L HG3  1 
ATOM   7440 H HD2  . LYS C 3 189 ? -39.883 28.394 14.970  1.00 72.80 ? 189 LYS L HD2  1 
ATOM   7441 H HD3  . LYS C 3 189 ? -39.782 29.115 13.557  1.00 72.80 ? 189 LYS L HD3  1 
ATOM   7442 H HE2  . LYS C 3 189 ? -38.650 26.573 13.798  1.00 76.33 ? 189 LYS L HE2  1 
ATOM   7443 H HE3  . LYS C 3 189 ? -40.228 26.673 13.637  1.00 76.33 ? 189 LYS L HE3  1 
ATOM   7444 H HZ1  . LYS C 3 189 ? -39.194 26.407 11.618  1.00 74.11 ? 189 LYS L HZ1  1 
ATOM   7445 H HZ2  . LYS C 3 189 ? -39.911 27.666 11.633  1.00 74.11 ? 189 LYS L HZ2  1 
ATOM   7446 H HZ3  . LYS C 3 189 ? -38.471 27.651 11.786  1.00 74.11 ? 189 LYS L HZ3  1 
ATOM   7447 N N    . HIS C 3 190 ? -36.622 26.264 18.023  1.00 42.38 ? 190 HIS L N    1 
ATOM   7448 C CA   . HIS C 3 190 ? -36.596 24.860 18.422  1.00 37.85 ? 190 HIS L CA   1 
ATOM   7449 C C    . HIS C 3 190 ? -36.457 24.697 19.934  1.00 37.65 ? 190 HIS L C    1 
ATOM   7450 O O    . HIS C 3 190 ? -36.213 25.652 20.673  1.00 42.87 ? 190 HIS L O    1 
ATOM   7451 C CB   . HIS C 3 190 ? -35.475 24.129 17.683  1.00 38.71 ? 190 HIS L CB   1 
ATOM   7452 C CG   . HIS C 3 190 ? -35.591 24.224 16.197  1.00 40.73 ? 190 HIS L CG   1 
ATOM   7453 N ND1  . HIS C 3 190 ? -36.400 23.384 15.465  1.00 48.53 ? 190 HIS L ND1  1 
ATOM   7454 C CD2  . HIS C 3 190 ? -35.000 25.053 15.301  1.00 42.07 ? 190 HIS L CD2  1 
ATOM   7455 C CE1  . HIS C 3 190 ? -36.309 23.693 14.185  1.00 40.30 ? 190 HIS L CE1  1 
ATOM   7456 N NE2  . HIS C 3 190 ? -35.470 24.706 14.058  1.00 41.51 ? 190 HIS L NE2  1 
ATOM   7457 H H    . HIS C 3 190 ? -35.868 26.673 18.095  1.00 50.92 ? 190 HIS L H    1 
ATOM   7458 H HA   . HIS C 3 190 ? -37.444 24.454 18.186  1.00 45.49 ? 190 HIS L HA   1 
ATOM   7459 H HB2  . HIS C 3 190 ? -34.623 24.516 17.941  1.00 46.52 ? 190 HIS L HB2  1 
ATOM   7460 H HB3  . HIS C 3 190 ? -35.499 23.190 17.925  1.00 46.52 ? 190 HIS L HB3  1 
ATOM   7461 H HD1  . HIS C 3 190 ? -36.888 22.756 15.791  1.00 58.30 ? 190 HIS L HD1  1 
ATOM   7462 H HD2  . HIS C 3 190 ? -34.391 25.729 15.493  1.00 50.54 ? 190 HIS L HD2  1 
ATOM   7463 H HE1  . HIS C 3 190 ? -36.759 23.270 13.490  1.00 48.42 ? 190 HIS L HE1  1 
ATOM   7464 N N    . LYS C 3 191 ? -36.644 23.451 20.388  1.00 35.84 ? 191 LYS L N    1 
ATOM   7465 C CA   . LYS C 3 191 ? -36.744 23.123 21.811  1.00 39.16 ? 191 LYS L CA   1 
ATOM   7466 C C    . LYS C 3 191 ? -35.622 22.220 22.307  1.00 38.89 ? 191 LYS L C    1 
ATOM   7467 O O    . LYS C 3 191 ? -34.951 22.573 23.280  1.00 40.52 ? 191 LYS L O    1 
ATOM   7468 C CB   . LYS C 3 191 ? -38.088 22.453 22.123  1.00 45.41 ? 191 LYS L CB   1 
ATOM   7469 C CG   . LYS C 3 191 ? -39.273 23.066 21.407  1.00 52.06 ? 191 LYS L CG   1 
ATOM   7470 C CD   . LYS C 3 191 ? -40.264 21.998 20.951  1.00 56.62 ? 191 LYS L CD   1 
ATOM   7471 C CE   . LYS C 3 191 ? -39.926 21.477 19.560  1.00 56.31 ? 191 LYS L CE   1 
ATOM   7472 N NZ   . LYS C 3 191 ? -40.027 22.537 18.507  1.00 47.83 ? 191 LYS L NZ   1 
ATOM   7473 H H    . LYS C 3 191 ? -36.718 22.764 19.877  1.00 43.07 ? 191 LYS L H    1 
ATOM   7474 N N    . VAL C 3 192 ? -35.425 21.045 21.717  1.00 38.22 ? 192 VAL L N    1 
ATOM   7475 C CA   . VAL C 3 192 ? -34.454 20.084 22.232  1.00 37.88 ? 192 VAL L CA   1 
ATOM   7476 C C    . VAL C 3 192 ? -33.116 20.299 21.537  1.00 35.66 ? 192 VAL L C    1 
ATOM   7477 O O    . VAL C 3 192 ? -33.012 20.174 20.312  1.00 37.05 ? 192 VAL L O    1 
ATOM   7478 C CB   . VAL C 3 192 ? -34.930 18.639 22.043  1.00 43.60 ? 192 VAL L CB   1 
ATOM   7479 C CG1  . VAL C 3 192 ? -33.936 17.681 22.679  1.00 39.59 ? 192 VAL L CG1  1 
ATOM   7480 C CG2  . VAL C 3 192 ? -36.315 18.442 22.632  1.00 44.78 ? 192 VAL L CG2  1 
ATOM   7481 H H    . VAL C 3 192 ? -35.843 20.779 21.014  1.00 45.92 ? 192 VAL L H    1 
ATOM   7482 H HA   . VAL C 3 192 ? -34.337 20.253 23.180  1.00 45.52 ? 192 VAL L HA   1 
ATOM   7483 H HB   . VAL C 3 192 ? -34.985 18.446 21.094  1.00 52.38 ? 192 VAL L HB   1 
ATOM   7484 H HG11 . VAL C 3 192 ? -34.248 16.771 22.551  1.00 47.57 ? 192 VAL L HG11 1 
ATOM   7485 H HG12 . VAL C 3 192 ? -33.070 17.796 22.256  1.00 47.57 ? 192 VAL L HG12 1 
ATOM   7486 H HG13 . VAL C 3 192 ? -33.869 17.877 23.626  1.00 47.57 ? 192 VAL L HG13 1 
ATOM   7487 H HG21 . VAL C 3 192 ? -36.585 17.520 22.501  1.00 53.79 ? 192 VAL L HG21 1 
ATOM   7488 H HG22 . VAL C 3 192 ? -36.287 18.647 23.579  1.00 53.79 ? 192 VAL L HG22 1 
ATOM   7489 H HG23 . VAL C 3 192 ? -36.936 19.036 22.182  1.00 53.79 ? 192 VAL L HG23 1 
ATOM   7490 N N    . TYR C 3 193 ? -32.088 20.607 22.321  1.00 35.23 ? 193 TYR L N    1 
ATOM   7491 C CA   . TYR C 3 193 ? -30.724 20.732 21.823  1.00 31.22 ? 193 TYR L CA   1 
ATOM   7492 C C    . TYR C 3 193 ? -29.887 19.615 22.432  1.00 29.33 ? 193 TYR L C    1 
ATOM   7493 O O    . TYR C 3 193 ? -29.846 19.456 23.660  1.00 30.52 ? 193 TYR L O    1 
ATOM   7494 C CB   . TYR C 3 193 ? -30.200 22.116 22.172  1.00 31.41 ? 193 TYR L CB   1 
ATOM   7495 C CG   . TYR C 3 193 ? -30.831 23.171 21.305  1.00 31.07 ? 193 TYR L CG   1 
ATOM   7496 C CD1  . TYR C 3 193 ? -30.280 23.507 20.081  1.00 29.25 ? 193 TYR L CD1  1 
ATOM   7497 C CD2  . TYR C 3 193 ? -32.014 23.794 21.688  1.00 33.67 ? 193 TYR L CD2  1 
ATOM   7498 C CE1  . TYR C 3 193 ? -30.846 24.451 19.273  1.00 35.13 ? 193 TYR L CE1  1 
ATOM   7499 C CE2  . TYR C 3 193 ? -32.592 24.763 20.876  1.00 33.06 ? 193 TYR L CE2  1 
ATOM   7500 C CZ   . TYR C 3 193 ? -32.000 25.076 19.667  1.00 34.63 ? 193 TYR L CZ   1 
ATOM   7501 O OH   . TYR C 3 193 ? -32.532 26.028 18.832  1.00 37.83 ? 193 TYR L OH   1 
ATOM   7502 H H    . TYR C 3 193 ? -32.158 20.752 23.166  1.00 42.34 ? 193 TYR L H    1 
ATOM   7503 H HA   . TYR C 3 193 ? -30.677 20.622 20.860  1.00 37.53 ? 193 TYR L HA   1 
ATOM   7504 H HB2  . TYR C 3 193 ? -30.408 22.315 23.099  1.00 37.76 ? 193 TYR L HB2  1 
ATOM   7505 H HB3  . TYR C 3 193 ? -29.240 22.141 22.036  1.00 37.76 ? 193 TYR L HB3  1 
ATOM   7506 H HD1  . TYR C 3 193 ? -29.503 23.079 19.801  1.00 35.16 ? 193 TYR L HD1  1 
ATOM   7507 H HD2  . TYR C 3 193 ? -32.420 23.560 22.491  1.00 40.46 ? 193 TYR L HD2  1 
ATOM   7508 H HE1  . TYR C 3 193 ? -30.450 24.670 18.460  1.00 42.22 ? 193 TYR L HE1  1 
ATOM   7509 H HE2  . TYR C 3 193 ? -33.370 25.198 21.144  1.00 39.73 ? 193 TYR L HE2  1 
ATOM   7510 H HH   . TYR C 3 193 ? -33.266 26.300 19.137  1.00 45.46 ? 193 TYR L HH   1 
ATOM   7511 N N    . ALA C 3 194 ? -29.261 18.806 21.581  1.00 32.82 ? 194 ALA L N    1 
ATOM   7512 C CA   . ALA C 3 194 ? -28.573 17.638 22.099  1.00 31.17 ? 194 ALA L CA   1 
ATOM   7513 C C    . ALA C 3 194 ? -27.264 17.366 21.379  1.00 29.79 ? 194 ALA L C    1 
ATOM   7514 O O    . ALA C 3 194 ? -27.123 17.580 20.168  1.00 27.20 ? 194 ALA L O    1 
ATOM   7515 C CB   . ALA C 3 194 ? -29.472 16.409 22.020  1.00 38.65 ? 194 ALA L CB   1 
ATOM   7516 H H    . ALA C 3 194 ? -29.225 18.913 20.729  1.00 39.44 ? 194 ALA L H    1 
ATOM   7517 H HA   . ALA C 3 194 ? -28.332 17.818 23.021  1.00 37.46 ? 194 ALA L HA   1 
ATOM   7518 H HB1  . ALA C 3 194 ? -29.023 15.661 22.445  1.00 46.45 ? 194 ALA L HB1  1 
ATOM   7519 H HB2  . ALA C 3 194 ? -30.306 16.598 22.479  1.00 46.45 ? 194 ALA L HB2  1 
ATOM   7520 H HB3  . ALA C 3 194 ? -29.646 16.204 21.088  1.00 46.45 ? 194 ALA L HB3  1 
ATOM   7521 N N    . CYS C 3 195 ? -26.316 16.883 22.179  1.00 30.74 ? 195 CYS L N    1 
ATOM   7522 C CA   . CYS C 3 195 ? -24.968 16.540 21.758  1.00 29.43 ? 195 CYS L CA   1 
ATOM   7523 C C    . CYS C 3 195 ? -24.778 15.045 21.965  1.00 26.08 ? 195 CYS L C    1 
ATOM   7524 O O    . CYS C 3 195 ? -24.863 14.566 23.096  1.00 26.32 ? 195 CYS L O    1 
ATOM   7525 C CB   . CYS C 3 195 ? -23.944 17.339 22.575  1.00 32.60 ? 195 CYS L CB   1 
ATOM   7526 S SG   . CYS C 3 195 ? -22.269 17.029 22.076  1.00 40.26 ? 195 CYS L SG   1 
ATOM   7527 H H    . CYS C 3 195 ? -26.441 16.739 23.018  1.00 36.95 ? 195 CYS L H    1 
ATOM   7528 H HA   . CYS C 3 195 ? -24.840 16.739 20.818  1.00 35.38 ? 195 CYS L HA   1 
ATOM   7529 H HB2  . CYS C 3 195 ? -24.121 18.286 22.461  1.00 39.18 ? 195 CYS L HB2  1 
ATOM   7530 H HB3  . CYS C 3 195 ? -24.028 17.095 23.510  1.00 39.18 ? 195 CYS L HB3  1 
ATOM   7531 N N    . GLU C 3 196 ? -24.514 14.311 20.882  1.00 27.09 ? 196 GLU L N    1 
ATOM   7532 C CA   . GLU C 3 196 ? -24.330 12.867 20.947  1.00 28.98 ? 196 GLU L CA   1 
ATOM   7533 C C    . GLU C 3 196 ? -22.885 12.514 20.627  1.00 24.22 ? 196 GLU L C    1 
ATOM   7534 O O    . GLU C 3 196 ? -22.371 12.872 19.566  1.00 25.58 ? 196 GLU L O    1 
ATOM   7535 C CB   . GLU C 3 196 ? -25.270 12.158 19.981  1.00 32.95 ? 196 GLU L CB   1 
ATOM   7536 C CG   . GLU C 3 196 ? -24.967 10.672 19.793  1.00 41.39 ? 196 GLU L CG   1 
ATOM   7537 C CD   . GLU C 3 196 ? -25.508 10.136 18.479  1.00 48.06 ? 196 GLU L CD   1 
ATOM   7538 O OE1  . GLU C 3 196 ? -26.745 9.914  18.406  1.00 48.53 ? 196 GLU L OE1  1 
ATOM   7539 O OE2  . GLU C 3 196 ? -24.693 9.939  17.538  1.00 49.72 ? 196 GLU L OE2  1 
ATOM   7540 H H    . GLU C 3 196 ? -24.436 14.635 20.090  1.00 32.57 ? 196 GLU L H    1 
ATOM   7541 H HA   . GLU C 3 196 ? -24.522 12.561 21.847  1.00 34.84 ? 196 GLU L HA   1 
ATOM   7542 H HB2  . GLU C 3 196 ? -26.177 12.234 20.318  1.00 39.60 ? 196 GLU L HB2  1 
ATOM   7543 H HB3  . GLU C 3 196 ? -25.203 12.585 19.112  1.00 39.60 ? 196 GLU L HB3  1 
ATOM   7544 H HG2  . GLU C 3 196 ? -24.006 10.540 19.800  1.00 49.73 ? 196 GLU L HG2  1 
ATOM   7545 H HG3  . GLU C 3 196 ? -25.377 10.170 20.515  1.00 49.73 ? 196 GLU L HG3  1 
ATOM   7546 N N    . VAL C 3 197 ? -22.263 11.773 21.530  1.00 25.95 ? 197 VAL L N    1 
ATOM   7547 C CA   . VAL C 3 197 ? -20.828 11.532 21.523  1.00 26.47 ? 197 VAL L CA   1 
ATOM   7548 C C    . VAL C 3 197 ? -20.559 10.042 21.348  1.00 22.01 ? 197 VAL L C    1 
ATOM   7549 O O    . VAL C 3 197 ? -20.980 9.225  22.175  1.00 26.91 ? 197 VAL L O    1 
ATOM   7550 C CB   . VAL C 3 197 ? -20.186 12.066 22.814  1.00 23.48 ? 197 VAL L CB   1 
ATOM   7551 C CG1  . VAL C 3 197 ? -18.708 11.683 22.865  1.00 21.50 ? 197 VAL L CG1  1 
ATOM   7552 C CG2  . VAL C 3 197 ? -20.345 13.556 22.901  1.00 26.09 ? 197 VAL L CG2  1 
ATOM   7553 H H    . VAL C 3 197 ? -22.667 11.384 22.182  1.00 31.20 ? 197 VAL L H    1 
ATOM   7554 H HA   . VAL C 3 197 ? -20.435 11.975 20.755  1.00 31.83 ? 197 VAL L HA   1 
ATOM   7555 H HB   . VAL C 3 197 ? -20.632 11.669 23.578  1.00 28.24 ? 197 VAL L HB   1 
ATOM   7556 H HG11 . VAL C 3 197 ? -18.248 12.278 23.477  1.00 25.86 ? 197 VAL L HG11 1 
ATOM   7557 H HG12 . VAL C 3 197 ? -18.630 10.767 23.173  1.00 25.86 ? 197 VAL L HG12 1 
ATOM   7558 H HG13 . VAL C 3 197 ? -18.330 11.766 21.976  1.00 25.86 ? 197 VAL L HG13 1 
ATOM   7559 H HG21 . VAL C 3 197 ? -19.819 13.887 23.645  1.00 31.37 ? 197 VAL L HG21 1 
ATOM   7560 H HG22 . VAL C 3 197 ? -20.035 13.955 22.073  1.00 31.37 ? 197 VAL L HG22 1 
ATOM   7561 H HG23 . VAL C 3 197 ? -21.282 13.765 23.039  1.00 31.37 ? 197 VAL L HG23 1 
ATOM   7562 N N    . THR C 3 198 ? -19.810 9.697  20.305  1.00 24.90 ? 198 THR L N    1 
ATOM   7563 C CA   . THR C 3 198 ? -19.295 8.340  20.151  1.00 24.25 ? 198 THR L CA   1 
ATOM   7564 C C    . THR C 3 198 ? -17.794 8.332  20.401  1.00 23.72 ? 198 THR L C    1 
ATOM   7565 O O    . THR C 3 198 ? -17.059 9.203  19.911  1.00 25.96 ? 198 THR L O    1 
ATOM   7566 C CB   . THR C 3 198 ? -19.584 7.766  18.771  1.00 30.55 ? 198 THR L CB   1 
ATOM   7567 O OG1  . THR C 3 198 ? -18.764 8.418  17.804  1.00 40.43 ? 198 THR L OG1  1 
ATOM   7568 C CG2  . THR C 3 198 ? -21.039 7.991  18.379  1.00 25.27 ? 198 THR L CG2  1 
ATOM   7569 H H    . THR C 3 198 ? -19.586 10.234 19.671  1.00 29.94 ? 198 THR L H    1 
ATOM   7570 H HA   . THR C 3 198 ? -19.729 7.774  20.808  1.00 29.16 ? 198 THR L HA   1 
ATOM   7571 H HB   . THR C 3 198 ? -19.404 6.812  18.786  1.00 36.72 ? 198 THR L HB   1 
ATOM   7572 H HG1  . THR C 3 198 ? -18.932 8.120  17.037  1.00 48.57 ? 198 THR L HG1  1 
ATOM   7573 H HG21 . THR C 3 198 ? -21.215 7.591  17.513  1.00 30.38 ? 198 THR L HG21 1 
ATOM   7574 H HG22 . THR C 3 198 ? -21.627 7.587  19.037  1.00 30.38 ? 198 THR L HG22 1 
ATOM   7575 H HG23 . THR C 3 198 ? -21.227 8.941  18.331  1.00 30.38 ? 198 THR L HG23 1 
ATOM   7576 N N    . HIS C 3 199 ? -17.364 7.383  21.208  1.00 21.00 ? 199 HIS L N    1 
ATOM   7577 C CA   . HIS C 3 199 ? -15.967 7.308  21.592  1.00 21.40 ? 199 HIS L CA   1 
ATOM   7578 C C    . HIS C 3 199 ? -15.678 5.872  21.948  1.00 24.40 ? 199 HIS L C    1 
ATOM   7579 O O    . HIS C 3 199 ? -16.585 5.107  22.273  1.00 24.72 ? 199 HIS L O    1 
ATOM   7580 C CB   . HIS C 3 199 ? -15.635 8.232  22.770  1.00 19.89 ? 199 HIS L CB   1 
ATOM   7581 C CG   . HIS C 3 199 ? -14.178 8.234  23.129  1.00 17.90 ? 199 HIS L CG   1 
ATOM   7582 N ND1  . HIS C 3 199 ? -13.646 7.404  24.097  1.00 17.26 ? 199 HIS L ND1  1 
ATOM   7583 C CD2  . HIS C 3 199 ? -13.124 8.863  22.565  1.00 17.32 ? 199 HIS L CD2  1 
ATOM   7584 C CE1  . HIS C 3 199 ? -12.338 7.584  24.168  1.00 17.37 ? 199 HIS L CE1  1 
ATOM   7585 N NE2  . HIS C 3 199 ? -11.997 8.459  23.241  1.00 16.37 ? 199 HIS L NE2  1 
ATOM   7586 H H    . HIS C 3 199 ? -17.861 6.769  21.548  1.00 25.26 ? 199 HIS L H    1 
ATOM   7587 H HA   . HIS C 3 199 ? -15.409 7.580  20.847  1.00 25.74 ? 199 HIS L HA   1 
ATOM   7588 H HB2  . HIS C 3 199 ? -15.886 9.140  22.537  1.00 23.93 ? 199 HIS L HB2  1 
ATOM   7589 H HB3  . HIS C 3 199 ? -16.134 7.939  23.549  1.00 23.93 ? 199 HIS L HB3  1 
ATOM   7590 H HD2  . HIS C 3 199 ? -13.154 9.459  21.851  1.00 20.84 ? 199 HIS L HD2  1 
ATOM   7591 H HE1  . HIS C 3 199 ? -11.760 7.167  24.766  1.00 20.90 ? 199 HIS L HE1  1 
ATOM   7592 H HE2  . HIS C 3 199 ? -11.197 8.734  23.085  1.00 19.71 ? 199 HIS L HE2  1 
ATOM   7593 N N    . GLN C 3 200 ? -14.394 5.529  21.938  1.00 24.18 ? 200 GLN L N    1 
ATOM   7594 C CA   . GLN C 3 200 ? -14.041 4.150  22.214  1.00 23.19 ? 200 GLN L CA   1 
ATOM   7595 C C    . GLN C 3 200 ? -14.342 3.725  23.642  1.00 24.87 ? 200 GLN L C    1 
ATOM   7596 O O    . GLN C 3 200 ? -14.668 2.556  23.868  1.00 32.08 ? 200 GLN L O    1 
ATOM   7597 C CB   . GLN C 3 200 ? -12.581 3.905  21.926  1.00 23.30 ? 200 GLN L CB   1 
ATOM   7598 C CG   . GLN C 3 200 ? -12.456 2.419  22.192  1.00 32.32 ? 200 GLN L CG   1 
ATOM   7599 C CD   . GLN C 3 200 ? -12.131 1.699  21.006  1.00 23.01 ? 200 GLN L CD   1 
ATOM   7600 O OE1  . GLN C 3 200 ? -12.117 2.259  19.911  1.00 25.94 ? 200 GLN L OE1  1 
ATOM   7601 N NE2  . GLN C 3 200 ? -12.154 0.412  21.147  1.00 20.11 ? 200 GLN L NE2  1 
ATOM   7602 H H    . GLN C 3 200 ? -13.735 6.058  21.781  1.00 29.07 ? 200 GLN L H    1 
ATOM   7603 H HA   . GLN C 3 200 ? -14.577 3.602  21.620  1.00 27.88 ? 200 GLN L HA   1 
ATOM   7604 H HB2  . GLN C 3 200 ? -12.360 4.111  21.004  1.00 28.02 ? 200 GLN L HB2  1 
ATOM   7605 H HB3  . GLN C 3 200 ? -12.010 4.412  22.525  1.00 28.02 ? 200 GLN L HB3  1 
ATOM   7606 H HG2  . GLN C 3 200 ? -11.753 2.268  22.842  1.00 38.84 ? 200 GLN L HG2  1 
ATOM   7607 H HG3  . GLN C 3 200 ? -13.300 2.082  22.531  1.00 38.84 ? 200 GLN L HG3  1 
ATOM   7608 H HE21 . GLN C 3 200 ? -12.353 0.066  21.909  1.00 24.19 ? 200 GLN L HE21 1 
ATOM   7609 H HE22 . GLN C 3 200 ? -11.969 -0.097 20.479  1.00 24.19 ? 200 GLN L HE22 1 
ATOM   7610 N N    . GLY C 3 201 ? -14.253 4.607  24.597  1.00 19.39 ? 201 GLY L N    1 
ATOM   7611 C CA   . GLY C 3 201 ? -14.561 4.196  25.946  1.00 22.70 ? 201 GLY L CA   1 
ATOM   7612 C C    . GLY C 3 201 ? -16.035 4.103  26.267  1.00 22.19 ? 201 GLY L C    1 
ATOM   7613 O O    . GLY C 3 201 ? -16.365 3.933  27.442  1.00 26.45 ? 201 GLY L O    1 
ATOM   7614 H H    . GLY C 3 201 ? -14.024 5.430  24.498  1.00 23.33 ? 201 GLY L H    1 
ATOM   7615 H HA2  . GLY C 3 201 ? -14.169 3.322  26.101  1.00 27.30 ? 201 GLY L HA2  1 
ATOM   7616 H HA3  . GLY C 3 201 ? -14.164 4.833  26.562  1.00 27.30 ? 201 GLY L HA3  1 
ATOM   7617 N N    . LEU C 3 202 ? -16.908 4.299  25.285  1.00 24.43 ? 202 LEU L N    1 
ATOM   7618 C CA   . LEU C 3 202 ? -18.355 4.275  25.483  1.00 29.40 ? 202 LEU L CA   1 
ATOM   7619 C C    . LEU C 3 202 ? -18.911 3.112  24.685  1.00 29.78 ? 202 LEU L C    1 
ATOM   7620 O O    . LEU C 3 202 ? -18.819 3.111  23.454  1.00 30.15 ? 202 LEU L O    1 
ATOM   7621 C CB   . LEU C 3 202 ? -19.003 5.581  25.020  1.00 25.24 ? 202 LEU L CB   1 
ATOM   7622 C CG   . LEU C 3 202 ? -18.511 6.877  25.663  1.00 24.48 ? 202 LEU L CG   1 
ATOM   7623 C CD1  . LEU C 3 202 ? -19.020 8.093  24.868  1.00 23.42 ? 202 LEU L CD1  1 
ATOM   7624 C CD2  . LEU C 3 202 ? -18.926 6.937  27.117  1.00 28.58 ? 202 LEU L CD2  1 
ATOM   7625 H H    . LEU C 3 202 ? -16.679 4.452  24.470  1.00 29.38 ? 202 LEU L H    1 
ATOM   7626 H HA   . LEU C 3 202 ? -18.554 4.153  26.424  1.00 35.34 ? 202 LEU L HA   1 
ATOM   7627 H HB2  . LEU C 3 202 ? -18.851 5.666  24.066  1.00 30.35 ? 202 LEU L HB2  1 
ATOM   7628 H HB3  . LEU C 3 202 ? -19.954 5.521  25.201  1.00 30.35 ? 202 LEU L HB3  1 
ATOM   7629 H HG   . LEU C 3 202 ? -17.541 6.905  25.644  1.00 29.44 ? 202 LEU L HG   1 
ATOM   7630 H HD11 . LEU C 3 202 ? -18.737 8.905  25.317  1.00 28.17 ? 202 LEU L HD11 1 
ATOM   7631 H HD12 . LEU C 3 202 ? -18.648 8.064  23.973  1.00 28.17 ? 202 LEU L HD12 1 
ATOM   7632 H HD13 . LEU C 3 202 ? -19.989 8.060  24.825  1.00 28.17 ? 202 LEU L HD13 1 
ATOM   7633 H HD21 . LEU C 3 202 ? -18.601 7.766  27.504  1.00 34.35 ? 202 LEU L HD21 1 
ATOM   7634 H HD22 . LEU C 3 202 ? -19.893 6.904  27.171  1.00 34.35 ? 202 LEU L HD22 1 
ATOM   7635 H HD23 . LEU C 3 202 ? -18.542 6.180  27.587  1.00 34.35 ? 202 LEU L HD23 1 
ATOM   7636 N N    . SER C 3 203 ? -19.528 2.152  25.377  1.00 35.60 ? 203 SER L N    1 
ATOM   7637 C CA   . SER C 3 203 ? -20.149 1.018  24.687  1.00 40.23 ? 203 SER L CA   1 
ATOM   7638 C C    . SER C 3 203 ? -21.163 1.480  23.646  1.00 40.92 ? 203 SER L C    1 
ATOM   7639 O O    . SER C 3 203 ? -21.290 0.879  22.571  1.00 43.75 ? 203 SER L O    1 
ATOM   7640 C CB   . SER C 3 203 ? -20.823 0.096  25.700  1.00 37.37 ? 203 SER L CB   1 
ATOM   7641 O OG   . SER C 3 203 ? -20.074 0.025  26.895  1.00 48.05 ? 203 SER L OG   1 
ATOM   7642 H H    . SER C 3 203 ? -19.601 2.132  26.234  1.00 42.79 ? 203 SER L H    1 
ATOM   7643 H HA   . SER C 3 203 ? -19.453 0.520  24.230  1.00 48.34 ? 203 SER L HA   1 
ATOM   7644 H HB2  . SER C 3 203 ? -21.707 0.441  25.902  1.00 44.90 ? 203 SER L HB2  1 
ATOM   7645 H HB3  . SER C 3 203 ? -20.893 -0.793 25.319  1.00 44.90 ? 203 SER L HB3  1 
ATOM   7646 H HG   . SER C 3 203 ? -20.551 -0.279 27.516  1.00 57.72 ? 203 SER L HG   1 
ATOM   7647 N N    . SER C 3 204 ? -21.879 2.555  23.941  1.00 35.74 ? 204 SER L N    1 
ATOM   7648 C CA   . SER C 3 204 ? -22.860 3.130  23.037  1.00 39.22 ? 204 SER L CA   1 
ATOM   7649 C C    . SER C 3 204 ? -22.882 4.633  23.247  1.00 34.69 ? 204 SER L C    1 
ATOM   7650 O O    . SER C 3 204 ? -22.482 5.123  24.307  1.00 34.28 ? 204 SER L O    1 
ATOM   7651 C CB   . SER C 3 204 ? -24.255 2.534  23.273  1.00 42.11 ? 204 SER L CB   1 
ATOM   7652 O OG   . SER C 3 204 ? -24.696 2.730  24.611  1.00 45.65 ? 204 SER L OG   1 
ATOM   7653 H H    . SER C 3 204 ? -21.811 2.983  24.684  1.00 42.95 ? 204 SER L H    1 
ATOM   7654 H HA   . SER C 3 204 ? -22.602 2.953  22.119  1.00 47.13 ? 204 SER L HA   1 
ATOM   7655 H HB2  . SER C 3 204 ? -24.883 2.965  22.672  1.00 50.59 ? 204 SER L HB2  1 
ATOM   7656 H HB3  . SER C 3 204 ? -24.222 1.582  23.092  1.00 50.59 ? 204 SER L HB3  1 
ATOM   7657 H HG   . SER C 3 204 ? -25.398 2.290  24.750  1.00 54.84 ? 204 SER L HG   1 
ATOM   7658 N N    . PRO C 3 205 ? -23.370 5.388  22.269  1.00 34.96 ? 205 PRO L N    1 
ATOM   7659 C CA   . PRO C 3 205 ? -23.258 6.847  22.337  1.00 36.36 ? 205 PRO L CA   1 
ATOM   7660 C C    . PRO C 3 205 ? -23.906 7.430  23.587  1.00 38.88 ? 205 PRO L C    1 
ATOM   7661 O O    . PRO C 3 205 ? -24.972 6.992  24.020  1.00 41.90 ? 205 PRO L O    1 
ATOM   7662 C CB   . PRO C 3 205 ? -23.989 7.302  21.074  1.00 36.73 ? 205 PRO L CB   1 
ATOM   7663 C CG   . PRO C 3 205 ? -23.799 6.187  20.126  1.00 37.22 ? 205 PRO L CG   1 
ATOM   7664 C CD   . PRO C 3 205 ? -23.852 4.946  20.949  1.00 37.78 ? 205 PRO L CD   1 
ATOM   7665 H HA   . PRO C 3 205 ? -22.325 7.112  22.314  1.00 43.69 ? 205 PRO L HA   1 
ATOM   7666 H HB2  . PRO C 3 205 ? -24.929 7.442  21.265  1.00 44.13 ? 205 PRO L HB2  1 
ATOM   7667 H HB3  . PRO C 3 205 ? -23.593 8.120  20.736  1.00 44.13 ? 205 PRO L HB3  1 
ATOM   7668 H HG2  . PRO C 3 205 ? -24.509 6.194  19.465  1.00 44.72 ? 205 PRO L HG2  1 
ATOM   7669 H HG3  . PRO C 3 205 ? -22.938 6.273  19.687  1.00 44.72 ? 205 PRO L HG3  1 
ATOM   7670 H HD2  . PRO C 3 205 ? -24.760 4.611  21.009  1.00 45.40 ? 205 PRO L HD2  1 
ATOM   7671 H HD3  . PRO C 3 205 ? -23.270 4.263  20.580  1.00 45.40 ? 205 PRO L HD3  1 
ATOM   7672 N N    . VAL C 3 206 ? -23.261 8.429  24.154  1.00 33.58 ? 206 VAL L N    1 
ATOM   7673 C CA   . VAL C 3 206 ? -23.839 9.243  25.217  1.00 31.53 ? 206 VAL L CA   1 
ATOM   7674 C C    . VAL C 3 206 ? -24.455 10.475 24.584  1.00 33.75 ? 206 VAL L C    1 
ATOM   7675 O O    . VAL C 3 206 ? -23.908 11.038 23.629  1.00 32.45 ? 206 VAL L O    1 
ATOM   7676 C CB   . VAL C 3 206 ? -22.784 9.640  26.270  1.00 35.58 ? 206 VAL L CB   1 
ATOM   7677 C CG1  . VAL C 3 206 ? -23.280 10.809 27.105  1.00 35.60 ? 206 VAL L CG1  1 
ATOM   7678 C CG2  . VAL C 3 206 ? -22.471 8.465  27.184  1.00 40.42 ? 206 VAL L CG2  1 
ATOM   7679 H H    . VAL C 3 206 ? -22.463 8.666  23.939  1.00 40.36 ? 206 VAL L H    1 
ATOM   7680 H HA   . VAL C 3 206 ? -24.526 8.729  25.669  1.00 37.89 ? 206 VAL L HA   1 
ATOM   7681 H HB   . VAL C 3 206 ? -21.974 9.904  25.806  1.00 42.75 ? 206 VAL L HB   1 
ATOM   7682 H HG11 . VAL C 3 206 ? -22.606 11.033 27.766  1.00 42.78 ? 206 VAL L HG11 1 
ATOM   7683 H HG12 . VAL C 3 206 ? -23.438 11.569 26.523  1.00 42.78 ? 206 VAL L HG12 1 
ATOM   7684 H HG13 . VAL C 3 206 ? -24.105 10.554 27.547  1.00 42.78 ? 206 VAL L HG13 1 
ATOM   7685 H HG21 . VAL C 3 206 ? -21.810 8.741  27.838  1.00 48.56 ? 206 VAL L HG21 1 
ATOM   7686 H HG22 . VAL C 3 206 ? -23.286 8.190  27.634  1.00 48.56 ? 206 VAL L HG22 1 
ATOM   7687 H HG23 . VAL C 3 206 ? -22.124 7.734  26.650  1.00 48.56 ? 206 VAL L HG23 1 
ATOM   7688 N N    . THR C 3 207 ? -25.611 10.880 25.108  1.00 31.68 ? 207 THR L N    1 
ATOM   7689 C CA   . THR C 3 207 ? -26.286 12.095 24.691  1.00 28.98 ? 207 THR L CA   1 
ATOM   7690 C C    . THR C 3 207 ? -26.499 12.968 25.916  1.00 30.32 ? 207 THR L C    1 
ATOM   7691 O O    . THR C 3 207 ? -26.958 12.491 26.959  1.00 30.91 ? 207 THR L O    1 
ATOM   7692 C CB   . THR C 3 207 ? -27.622 11.794 23.996  1.00 32.99 ? 207 THR L CB   1 
ATOM   7693 O OG1  . THR C 3 207 ? -27.383 10.982 22.836  1.00 33.11 ? 207 THR L OG1  1 
ATOM   7694 C CG2  . THR C 3 207 ? -28.301 13.098 23.574  1.00 33.80 ? 207 THR L CG2  1 
ATOM   7695 H H    . THR C 3 207 ? -26.031 10.452 25.725  1.00 38.08 ? 207 THR L H    1 
ATOM   7696 H HA   . THR C 3 207 ? -25.736 12.577 24.054  1.00 34.83 ? 207 THR L HA   1 
ATOM   7697 H HB   . THR C 3 207 ? -28.212 11.322 24.605  1.00 39.65 ? 207 THR L HB   1 
ATOM   7698 H HG1  . THR C 3 207 ? -28.114 10.762 22.484  1.00 39.79 ? 207 THR L HG1  1 
ATOM   7699 H HG21 . THR C 3 207 ? -29.002 12.913 22.930  1.00 40.62 ? 207 THR L HG21 1 
ATOM   7700 H HG22 . THR C 3 207 ? -28.690 13.535 24.347  1.00 40.62 ? 207 THR L HG22 1 
ATOM   7701 H HG23 . THR C 3 207 ? -27.651 13.694 23.169  1.00 40.62 ? 207 THR L HG23 1 
ATOM   7702 N N    . LYS C 3 208 ? -26.119 14.235 25.783  1.00 29.78 ? 208 LYS L N    1 
ATOM   7703 C CA   . LYS C 3 208 ? -26.428 15.298 26.728  1.00 27.44 ? 208 LYS L CA   1 
ATOM   7704 C C    . LYS C 3 208 ? -27.283 16.305 25.975  1.00 30.23 ? 208 LYS L C    1 
ATOM   7705 O O    . LYS C 3 208 ? -26.978 16.663 24.833  1.00 30.00 ? 208 LYS L O    1 
ATOM   7706 C CB   . LYS C 3 208 ? -25.155 15.961 27.292  1.00 28.45 ? 208 LYS L CB   1 
ATOM   7707 C CG   . LYS C 3 208 ? -24.212 15.005 28.006  1.00 29.50 ? 208 LYS L CG   1 
ATOM   7708 C CD   . LYS C 3 208 ? -24.743 14.586 29.356  1.00 31.91 ? 208 LYS L CD   1 
ATOM   7709 C CE   . LYS C 3 208 ? -24.035 13.357 29.881  1.00 34.51 ? 208 LYS L CE   1 
ATOM   7710 N NZ   . LYS C 3 208 ? -24.438 13.038 31.288  1.00 44.06 ? 208 LYS L NZ   1 
ATOM   7711 H H    . LYS C 3 208 ? -25.655 14.517 25.116  1.00 35.80 ? 208 LYS L H    1 
ATOM   7712 H HA   . LYS C 3 208 ? -26.914 14.954 27.493  1.00 32.99 ? 208 LYS L HA   1 
ATOM   7713 H HB2  . LYS C 3 208 ? -24.664 16.364 26.558  1.00 34.20 ? 208 LYS L HB2  1 
ATOM   7714 H HB3  . LYS C 3 208 ? -25.418 16.644 27.929  1.00 34.20 ? 208 LYS L HB3  1 
ATOM   7715 H HG2  . LYS C 3 208 ? -24.098 14.207 27.466  1.00 35.46 ? 208 LYS L HG2  1 
ATOM   7716 H HG3  . LYS C 3 208 ? -23.356 15.441 28.139  1.00 35.46 ? 208 LYS L HG3  1 
ATOM   7717 H HD2  . LYS C 3 208 ? -24.609 15.308 29.991  1.00 38.36 ? 208 LYS L HD2  1 
ATOM   7718 H HD3  . LYS C 3 208 ? -25.688 14.383 29.280  1.00 38.36 ? 208 LYS L HD3  1 
ATOM   7719 H HE2  . LYS C 3 208 ? -24.258 12.597 29.322  1.00 41.47 ? 208 LYS L HE2  1 
ATOM   7720 H HE3  . LYS C 3 208 ? -23.077 13.509 29.867  1.00 41.47 ? 208 LYS L HE3  1 
ATOM   7721 H HZ1  . LYS C 3 208 ? -24.007 12.313 31.571  1.00 52.93 ? 208 LYS L HZ1  1 
ATOM   7722 H HZ2  . LYS C 3 208 ? -24.239 13.720 31.823  1.00 52.93 ? 208 LYS L HZ2  1 
ATOM   7723 H HZ3  . LYS C 3 208 ? -25.314 12.886 31.326  1.00 52.93 ? 208 LYS L HZ3  1 
ATOM   7724 N N    . SER C 3 209 ? -28.351 16.765 26.620  1.00 30.88 ? 209 SER L N    1 
ATOM   7725 C CA   . SER C 3 209 ? -29.306 17.634 25.963  1.00 32.33 ? 209 SER L CA   1 
ATOM   7726 C C    . SER C 3 209 ? -29.887 18.584 26.991  1.00 26.02 ? 209 SER L C    1 
ATOM   7727 O O    . SER C 3 209 ? -29.783 18.368 28.202  1.00 30.99 ? 209 SER L O    1 
ATOM   7728 C CB   . SER C 3 209 ? -30.422 16.834 25.320  1.00 35.01 ? 209 SER L CB   1 
ATOM   7729 O OG   . SER C 3 209 ? -31.169 16.218 26.334  1.00 36.35 ? 209 SER L OG   1 
ATOM   7730 H H    . SER C 3 209 ? -28.541 16.584 27.439  1.00 37.12 ? 209 SER L H    1 
ATOM   7731 H HA   . SER C 3 209 ? -28.854 18.152 25.279  1.00 38.86 ? 209 SER L HA   1 
ATOM   7732 H HB2  . SER C 3 209 ? -30.995 17.427 24.809  1.00 42.07 ? 209 SER L HB2  1 
ATOM   7733 H HB3  . SER C 3 209 ? -30.043 16.156 24.738  1.00 42.07 ? 209 SER L HB3  1 
ATOM   7734 H HG   . SER C 3 209 ? -31.894 15.930 26.023  1.00 43.68 ? 209 SER L HG   1 
ATOM   7735 N N    . PHE C 3 210 ? -30.445 19.675 26.484  1.00 31.50 ? 210 PHE L N    1 
ATOM   7736 C CA   . PHE C 3 210 ? -31.249 20.585 27.279  1.00 32.09 ? 210 PHE L CA   1 
ATOM   7737 C C    . PHE C 3 210 ? -32.439 21.028 26.439  1.00 32.62 ? 210 PHE L C    1 
ATOM   7738 O O    . PHE C 3 210 ? -32.484 20.841 25.211  1.00 30.20 ? 210 PHE L O    1 
ATOM   7739 C CB   . PHE C 3 210 ? -30.427 21.794 27.753  1.00 29.02 ? 210 PHE L CB   1 
ATOM   7740 C CG   . PHE C 3 210 ? -29.947 22.673 26.638  1.00 30.74 ? 210 PHE L CG   1 
ATOM   7741 C CD1  . PHE C 3 210 ? -30.754 23.684 26.128  1.00 30.00 ? 210 PHE L CD1  1 
ATOM   7742 C CD2  . PHE C 3 210 ? -28.700 22.475 26.082  1.00 27.92 ? 210 PHE L CD2  1 
ATOM   7743 C CE1  . PHE C 3 210 ? -30.333 24.487 25.111  1.00 29.49 ? 210 PHE L CE1  1 
ATOM   7744 C CE2  . PHE C 3 210 ? -28.260 23.284 25.042  1.00 26.07 ? 210 PHE L CE2  1 
ATOM   7745 C CZ   . PHE C 3 210 ? -29.088 24.288 24.548  1.00 28.19 ? 210 PHE L CZ   1 
ATOM   7746 H H    . PHE C 3 210 ? -30.370 19.914 25.661  1.00 37.86 ? 210 PHE L H    1 
ATOM   7747 H HA   . PHE C 3 210 ? -31.586 20.135 28.070  1.00 38.57 ? 210 PHE L HA   1 
ATOM   7748 H HB2  . PHE C 3 210 ? -30.979 22.334 28.340  1.00 34.88 ? 210 PHE L HB2  1 
ATOM   7749 H HB3  . PHE C 3 210 ? -29.648 21.472 28.233  1.00 34.88 ? 210 PHE L HB3  1 
ATOM   7750 H HD1  . PHE C 3 210 ? -31.601 23.815 26.490  1.00 36.07 ? 210 PHE L HD1  1 
ATOM   7751 H HD2  . PHE C 3 210 ? -28.151 21.797 26.404  1.00 33.56 ? 210 PHE L HD2  1 
ATOM   7752 H HE1  . PHE C 3 210 ? -30.883 25.167 24.796  1.00 35.45 ? 210 PHE L HE1  1 
ATOM   7753 H HE2  . PHE C 3 210 ? -27.415 23.155 24.677  1.00 31.34 ? 210 PHE L HE2  1 
ATOM   7754 H HZ   . PHE C 3 210 ? -28.804 24.823 23.842  1.00 33.89 ? 210 PHE L HZ   1 
ATOM   7755 N N    . ASN C 3 211 ? -33.414 21.614 27.131  1.00 35.56 ? 211 ASN L N    1 
ATOM   7756 C CA   . ASN C 3 211 ? -34.625 22.151 26.528  1.00 36.81 ? 211 ASN L CA   1 
ATOM   7757 C C    . ASN C 3 211 ? -34.534 23.670 26.604  1.00 27.13 ? 211 ASN L C    1 
ATOM   7758 O O    . ASN C 3 211 ? -34.384 24.226 27.697  1.00 37.50 ? 211 ASN L O    1 
ATOM   7759 C CB   . ASN C 3 211 ? -35.856 21.634 27.277  1.00 36.96 ? 211 ASN L CB   1 
ATOM   7760 C CG   . ASN C 3 211 ? -36.083 20.149 27.080  1.00 35.18 ? 211 ASN L CG   1 
ATOM   7761 O OD1  . ASN C 3 211 ? -35.921 19.631 25.976  1.00 43.30 ? 211 ASN L OD1  1 
ATOM   7762 N ND2  . ASN C 3 211 ? -36.461 19.450 28.160  1.00 38.97 ? 211 ASN L ND2  1 
ATOM   7763 H H    . ASN C 3 211 ? -33.393 21.715 27.985  1.00 42.73 ? 211 ASN L H    1 
ATOM   7764 H HA   . ASN C 3 211 ? -34.703 21.887 25.598  1.00 44.23 ? 211 ASN L HA   1 
ATOM   7765 H HB2  . ASN C 3 211 ? -35.740 21.796 28.227  1.00 44.42 ? 211 ASN L HB2  1 
ATOM   7766 H HB3  . ASN C 3 211 ? -36.642 22.103 26.955  1.00 44.42 ? 211 ASN L HB3  1 
ATOM   7767 H HD21 . ASN C 3 211 ? -36.564 19.848 28.915  1.00 46.83 ? 211 ASN L HD21 1 
ATOM   7768 H HD22 . ASN C 3 211 ? -36.602 18.604 28.097  1.00 46.83 ? 211 ASN L HD22 1 
ATOM   7769 N N    . ARG C 3 212 ? -34.541 24.331 25.459  1.00 35.65 ? 212 ARG L N    1 
ATOM   7770 C CA   . ARG C 3 212 ? -34.430 25.781 25.456  1.00 36.91 ? 212 ARG L CA   1 
ATOM   7771 C C    . ARG C 3 212 ? -35.392 26.360 26.484  1.00 44.21 ? 212 ARG L C    1 
ATOM   7772 O O    . ARG C 3 212 ? -36.604 26.147 26.398  1.00 37.05 ? 212 ARG L O    1 
ATOM   7773 C CB   . ARG C 3 212 ? -34.719 26.333 24.060  1.00 36.48 ? 212 ARG L CB   1 
ATOM   7774 C CG   . ARG C 3 212 ? -34.473 27.832 23.962  1.00 35.69 ? 212 ARG L CG   1 
ATOM   7775 C CD   . ARG C 3 212 ? -35.061 28.423 22.679  1.00 41.09 ? 212 ARG L CD   1 
ATOM   7776 N NE   . ARG C 3 212 ? -36.220 27.693 22.192  1.00 57.11 ? 212 ARG L NE   1 
ATOM   7777 C CZ   . ARG C 3 212 ? -37.454 28.173 22.210  1.00 50.00 ? 212 ARG L CZ   1 
ATOM   7778 N NH1  . ARG C 3 212 ? -37.726 29.371 22.722  1.00 48.26 ? 212 ARG L NH1  1 
ATOM   7779 N NH2  . ARG C 3 212 ? -38.437 27.435 21.707  1.00 45.53 ? 212 ARG L NH2  1 
ATOM   7780 N N    . GLY C 3 213 ? -34.838 27.044 27.483  1.00 38.77 ? 213 GLY L N    1 
ATOM   7781 C CA   . GLY C 3 213 ? -35.580 27.389 28.682  1.00 41.31 ? 213 GLY L CA   1 
ATOM   7782 C C    . GLY C 3 213 ? -35.755 26.214 29.623  1.00 40.54 ? 213 GLY L C    1 
ATOM   7783 O O    . GLY C 3 213 ? -35.206 26.172 30.724  1.00 49.59 ? 213 GLY L O    1 
HETATM 7784 C C1   . NAG D 4 .   ? 22.681  2.702  -5.998  1.00 29.90 ? 1   NAG B C1   1 
HETATM 7785 C C2   . NAG D 4 .   ? 22.144  1.817  -7.083  1.00 29.19 ? 1   NAG B C2   1 
HETATM 7786 C C3   . NAG D 4 .   ? 20.834  1.188  -6.630  1.00 33.99 ? 1   NAG B C3   1 
HETATM 7787 C C4   . NAG D 4 .   ? 20.984  0.469  -5.294  1.00 38.72 ? 1   NAG B C4   1 
HETATM 7788 C C5   . NAG D 4 .   ? 21.604  1.396  -4.256  1.00 37.46 ? 1   NAG B C5   1 
HETATM 7789 C C6   . NAG D 4 .   ? 21.856  0.729  -2.912  1.00 40.34 ? 1   NAG B C6   1 
HETATM 7790 C C7   . NAG D 4 .   ? 22.726  2.479  -9.383  1.00 33.65 ? 1   NAG B C7   1 
HETATM 7791 C C8   . NAG D 4 .   ? 22.376  3.365  -10.527 1.00 26.86 ? 1   NAG B C8   1 
HETATM 7792 N N2   . NAG D 4 .   ? 21.945  2.586  -8.301  1.00 28.40 ? 1   NAG B N2   1 
HETATM 7793 O O3   . NAG D 4 .   ? 20.396  0.284  -7.632  1.00 37.08 ? 1   NAG B O3   1 
HETATM 7794 O O4   . NAG D 4 .   ? 19.686  0.111  -4.828  1.00 41.20 ? 1   NAG B O4   1 
HETATM 7795 O O5   . NAG D 4 .   ? 22.847  1.913  -4.758  1.00 31.11 ? 1   NAG B O5   1 
HETATM 7796 O O6   . NAG D 4 .   ? 22.738  -0.382 -2.989  1.00 45.88 ? 1   NAG B O6   1 
HETATM 7797 O O7   . NAG D 4 .   ? 23.659  1.686  -9.443  1.00 33.24 ? 1   NAG B O7   1 
HETATM 7798 C C1   . NAG D 4 .   ? 19.563  -1.310 -4.814  1.00 46.29 ? 2   NAG B C1   1 
HETATM 7799 C C2   . NAG D 4 .   ? 18.300  -1.587 -3.975  1.00 43.12 ? 2   NAG B C2   1 
HETATM 7800 C C3   . NAG D 4 .   ? 17.882  -3.065 -4.061  1.00 50.70 ? 2   NAG B C3   1 
HETATM 7801 C C4   . NAG D 4 .   ? 17.831  -3.517 -5.514  1.00 56.58 ? 2   NAG B C4   1 
HETATM 7802 C C5   . NAG D 4 .   ? 19.181  -3.249 -6.161  1.00 51.36 ? 2   NAG B C5   1 
HETATM 7803 C C6   . NAG D 4 .   ? 19.240  -3.640 -7.622  1.00 46.21 ? 2   NAG B C6   1 
HETATM 7804 C C7   . NAG D 4 .   ? 18.229  -0.005 -2.082  1.00 39.67 ? 2   NAG B C7   1 
HETATM 7805 C C8   . NAG D 4 .   ? 18.563  0.204  -0.634  1.00 30.33 ? 2   NAG B C8   1 
HETATM 7806 N N2   . NAG D 4 .   ? 18.527  -1.206 -2.590  1.00 42.43 ? 2   NAG B N2   1 
HETATM 7807 O O3   . NAG D 4 .   ? 16.602  -3.218 -3.454  1.00 45.02 ? 2   NAG B O3   1 
HETATM 7808 O O4   . NAG D 4 .   ? 17.394  -4.864 -5.710  1.00 69.23 ? 2   NAG B O4   1 
HETATM 7809 O O5   . NAG D 4 .   ? 19.412  -1.837 -6.101  1.00 46.53 ? 2   NAG B O5   1 
HETATM 7810 O O6   . NAG D 4 .   ? 18.029  -3.303 -8.288  1.00 54.35 ? 2   NAG B O6   1 
HETATM 7811 O O7   . NAG D 4 .   ? 17.718  0.874  -2.753  1.00 35.47 ? 2   NAG B O7   1 
HETATM 7812 C C1   . BMA D 4 .   ? 17.834  -5.924 -4.832  1.00 61.68 ? 3   BMA B C1   1 
HETATM 7813 C C2   . BMA D 4 .   ? 16.985  -5.913 -3.542  1.00 56.27 ? 3   BMA B C2   1 
HETATM 7814 C C3   . BMA D 4 .   ? 17.287  -7.106 -2.674  1.00 66.21 ? 3   BMA B C3   1 
HETATM 7815 C C4   . BMA D 4 .   ? 17.139  -8.419 -3.458  1.00 65.67 ? 3   BMA B C4   1 
HETATM 7816 C C5   . BMA D 4 .   ? 18.037  -8.391 -4.717  1.00 61.33 ? 3   BMA B C5   1 
HETATM 7817 C C6   . BMA D 4 .   ? 17.920  -9.661 -5.613  1.00 62.46 ? 3   BMA B C6   1 
HETATM 7818 O O2   . BMA D 4 .   ? 15.577  -5.975 -3.900  1.00 61.98 ? 3   BMA B O2   1 
HETATM 7819 O O3   . BMA D 4 .   ? 16.470  -7.115 -1.502  1.00 69.90 ? 3   BMA B O3   1 
HETATM 7820 O O4   . BMA D 4 .   ? 17.471  -9.548 -2.626  1.00 67.98 ? 3   BMA B O4   1 
HETATM 7821 O O5   . BMA D 4 .   ? 17.748  -7.210 -5.514  1.00 57.85 ? 3   BMA B O5   1 
HETATM 7822 O O6   . BMA D 4 .   ? 16.691  -9.617 -6.364  1.00 56.75 ? 3   BMA B O6   1 
HETATM 7823 C C1   . FUC D 4 .   ? 22.792  -1.066 -1.737  1.00 50.33 ? 4   FUC B C1   1 
HETATM 7824 C C2   . FUC D 4 .   ? 23.101  -2.485 -2.044  1.00 51.12 ? 4   FUC B C2   1 
HETATM 7825 C C3   . FUC D 4 .   ? 24.530  -2.654 -2.631  1.00 50.84 ? 4   FUC B C3   1 
HETATM 7826 C C4   . FUC D 4 .   ? 25.585  -1.912 -1.782  1.00 53.64 ? 4   FUC B C4   1 
HETATM 7827 C C5   . FUC D 4 .   ? 25.118  -0.513 -1.443  1.00 56.19 ? 4   FUC B C5   1 
HETATM 7828 C C6   . FUC D 4 .   ? 26.008  0.181  -0.396  1.00 47.18 ? 4   FUC B C6   1 
HETATM 7829 O O2   . FUC D 4 .   ? 22.113  -3.051 -2.931  1.00 52.51 ? 4   FUC B O2   1 
HETATM 7830 O O3   . FUC D 4 .   ? 24.921  -4.042 -2.694  1.00 62.11 ? 4   FUC B O3   1 
HETATM 7831 O O4   . FUC D 4 .   ? 25.849  -2.610 -0.563  1.00 61.98 ? 4   FUC B O4   1 
HETATM 7832 O O5   . FUC D 4 .   ? 23.772  -0.536 -0.923  1.00 56.45 ? 4   FUC B O5   1 
HETATM 7833 O O    . HOH E 5 .   ? 38.686  23.007 -15.502 1.00 21.21 ? 201 HOH A O    1 
HETATM 7834 O O    . HOH E 5 .   ? 22.702  25.960 -13.846 1.00 31.35 ? 202 HOH A O    1 
HETATM 7835 O O    . HOH E 5 .   ? 17.620  19.191 -24.443 1.00 26.36 ? 203 HOH A O    1 
HETATM 7836 O O    . HOH E 5 .   ? 10.005  20.822 -21.510 1.00 35.32 ? 204 HOH A O    1 
HETATM 7837 O O    . HOH E 5 .   ? 20.516  24.444 -24.001 1.00 29.12 ? 205 HOH A O    1 
HETATM 7838 O O    . HOH E 5 .   ? 36.983  -0.746 -3.912  1.00 36.75 ? 206 HOH A O    1 
HETATM 7839 O O    . HOH E 5 .   ? 19.797  27.874 -20.027 1.00 34.11 ? 207 HOH A O    1 
HETATM 7840 O O    . HOH E 5 .   ? 22.951  4.562  -2.506  1.00 35.28 ? 208 HOH A O    1 
HETATM 7841 O O    . HOH E 5 .   ? 7.809   22.858 -18.415 1.00 30.44 ? 209 HOH A O    1 
HETATM 7842 O O    . HOH E 5 .   ? 37.040  5.176  -16.929 1.00 35.70 ? 210 HOH A O    1 
HETATM 7843 O O    . HOH E 5 .   ? 40.761  22.210 -16.157 1.00 32.16 ? 211 HOH A O    1 
HETATM 7844 O O    . HOH E 5 .   ? 17.555  14.866 -20.964 1.00 16.12 ? 212 HOH A O    1 
HETATM 7845 O O    . HOH E 5 .   ? 47.390  15.632 -12.716 1.00 36.12 ? 213 HOH A O    1 
HETATM 7846 O O    . HOH E 5 .   ? 36.110  5.437  0.207   1.00 32.60 ? 214 HOH A O    1 
HETATM 7847 O O    . HOH E 5 .   ? 36.119  1.522  -13.988 1.00 33.24 ? 215 HOH A O    1 
HETATM 7848 O O    . HOH E 5 .   ? 9.314   13.981 -18.501 1.00 25.54 ? 216 HOH A O    1 
HETATM 7849 O O    . HOH E 5 .   ? 38.713  21.032 -7.779  1.00 37.49 ? 217 HOH A O    1 
HETATM 7850 O O    . HOH E 5 .   ? 31.632  28.139 -15.250 1.00 25.91 ? 218 HOH A O    1 
HETATM 7851 O O    . HOH E 5 .   ? 27.783  21.814 -4.688  1.00 23.86 ? 219 HOH A O    1 
HETATM 7852 O O    . HOH E 5 .   ? 32.054  2.289  -5.122  1.00 34.53 ? 220 HOH A O    1 
HETATM 7853 O O    . HOH E 5 .   ? 24.838  19.305 -10.046 1.00 12.95 ? 221 HOH A O    1 
HETATM 7854 O O    . HOH E 5 .   ? 24.899  8.764  -3.202  1.00 28.32 ? 222 HOH A O    1 
HETATM 7855 O O    . HOH E 5 .   ? 12.989  10.665 -13.307 1.00 19.64 ? 223 HOH A O    1 
HETATM 7856 O O    . HOH E 5 .   ? 36.054  31.583 -11.267 1.00 33.48 ? 224 HOH A O    1 
HETATM 7857 O O    . HOH E 5 .   ? 18.759  19.643 -5.025  1.00 11.64 ? 225 HOH A O    1 
HETATM 7858 O O    . HOH E 5 .   ? 32.623  25.674 -13.722 1.00 29.33 ? 226 HOH A O    1 
HETATM 7859 O O    . HOH E 5 .   ? 21.835  6.726  -8.572  1.00 26.58 ? 227 HOH A O    1 
HETATM 7860 O O    . HOH E 5 .   ? 18.817  9.173  -20.621 1.00 28.80 ? 228 HOH A O    1 
HETATM 7861 O O    . HOH E 5 .   ? 21.245  6.055  -15.503 1.00 26.21 ? 229 HOH A O    1 
HETATM 7862 O O    . HOH E 5 .   ? 10.296  15.528 -20.685 1.00 21.78 ? 230 HOH A O    1 
HETATM 7863 O O    . HOH E 5 .   ? 28.586  3.881  -8.432  1.00 21.34 ? 231 HOH A O    1 
HETATM 7864 O O    . HOH E 5 .   ? 12.453  18.591 -17.099 1.00 19.46 ? 232 HOH A O    1 
HETATM 7865 O O    . HOH E 5 .   ? 15.121  12.550 -9.374  1.00 16.70 ? 233 HOH A O    1 
HETATM 7866 O O    . HOH E 5 .   ? 14.849  20.609 -16.693 1.00 14.92 ? 234 HOH A O    1 
HETATM 7867 O O    . HOH E 5 .   ? 36.638  14.414 -19.987 1.00 31.82 ? 235 HOH A O    1 
HETATM 7868 O O    . HOH E 5 .   ? 37.810  22.952 -17.932 1.00 29.03 ? 236 HOH A O    1 
HETATM 7869 O O    . HOH E 5 .   ? 21.986  7.356  -5.187  1.00 24.31 ? 237 HOH A O    1 
HETATM 7870 O O    . HOH E 5 .   ? 15.287  26.965 -20.752 1.00 36.61 ? 238 HOH A O    1 
HETATM 7871 O O    . HOH E 5 .   ? 20.116  9.203  -9.191  1.00 20.44 ? 239 HOH A O    1 
HETATM 7872 O O    . HOH E 5 .   ? 39.998  2.709  -14.163 1.00 30.27 ? 240 HOH A O    1 
HETATM 7873 O O    . HOH E 5 .   ? 25.868  21.190 -6.281  1.00 14.37 ? 241 HOH A O    1 
HETATM 7874 O O    . HOH E 5 .   ? 21.065  20.707 -4.055  1.00 12.82 ? 242 HOH A O    1 
HETATM 7875 O O    . HOH E 5 .   ? 32.210  26.069 -16.697 1.00 30.27 ? 243 HOH A O    1 
HETATM 7876 O O    . HOH E 5 .   ? 25.895  1.225  -7.136  1.00 35.04 ? 244 HOH A O    1 
HETATM 7877 O O    . HOH E 5 .   ? 25.614  5.414  -9.542  1.00 22.10 ? 245 HOH A O    1 
HETATM 7878 O O    . HOH E 5 .   ? 11.132  20.608 -19.240 1.00 25.98 ? 246 HOH A O    1 
HETATM 7879 O O    . HOH E 5 .   ? 40.977  6.832  -15.007 1.00 30.71 ? 247 HOH A O    1 
HETATM 7880 O O    . HOH E 5 .   ? 28.047  5.582  -16.197 1.00 25.17 ? 248 HOH A O    1 
HETATM 7881 O O    . HOH E 5 .   ? 33.345  22.226 -0.209  1.00 26.95 ? 249 HOH A O    1 
HETATM 7882 O O    . HOH E 5 .   ? 25.470  27.146 -11.216 1.00 33.77 ? 250 HOH A O    1 
HETATM 7883 O O    . HOH E 5 .   ? 29.786  3.167  -4.620  1.00 33.57 ? 251 HOH A O    1 
HETATM 7884 O O    . HOH E 5 .   ? 27.975  23.819 -22.450 1.00 34.36 ? 252 HOH A O    1 
HETATM 7885 O O    . HOH E 5 .   ? 42.241  17.137 -7.545  1.00 23.84 ? 253 HOH A O    1 
HETATM 7886 O O    . HOH E 5 .   ? 39.729  22.691 -9.341  1.00 31.24 ? 254 HOH A O    1 
HETATM 7887 O O    . HOH E 5 .   ? 25.884  3.061  -10.720 1.00 33.68 ? 255 HOH A O    1 
HETATM 7888 O O    . HOH E 5 .   ? 33.613  -0.265 -11.561 1.00 32.27 ? 256 HOH A O    1 
HETATM 7889 O O    . HOH E 5 .   ? 34.874  8.386  -19.402 1.00 35.38 ? 257 HOH A O    1 
HETATM 7890 O O    . HOH E 5 .   ? 39.682  25.187 -15.613 1.00 35.19 ? 258 HOH A O    1 
HETATM 7891 O O    . HOH E 5 .   ? 29.063  3.576  -15.559 1.00 29.38 ? 259 HOH A O    1 
HETATM 7892 O O    . HOH E 5 .   ? 10.307  17.304 -17.971 1.00 22.47 ? 260 HOH A O    1 
HETATM 7893 O O    . HOH E 5 .   ? 47.383  16.369 -14.979 1.00 40.76 ? 261 HOH A O    1 
HETATM 7894 O O    . HOH E 5 .   ? 8.403   15.830 -16.782 1.00 31.79 ? 262 HOH A O    1 
HETATM 7895 O O    . HOH E 5 .   ? 24.349  10.729 -1.689  1.00 27.72 ? 263 HOH A O    1 
HETATM 7896 O O    . HOH E 5 .   ? 33.203  2.848  -17.287 1.00 42.29 ? 264 HOH A O    1 
HETATM 7897 O O    . HOH F 5 .   ? 17.233  43.129 1.642   1.00 33.92 ? 301 HOH H O    1 
HETATM 7898 O O    . HOH F 5 .   ? -18.326 36.211 14.061  1.00 33.60 ? 302 HOH H O    1 
HETATM 7899 O O    . HOH F 5 .   ? 0.794   23.166 -3.244  1.00 23.08 ? 303 HOH H O    1 
HETATM 7900 O O    . HOH F 5 .   ? -9.625  36.773 9.776   1.00 23.41 ? 304 HOH H O    1 
HETATM 7901 O O    . HOH F 5 .   ? 15.407  31.999 12.246  1.00 27.77 ? 305 HOH H O    1 
HETATM 7902 O O    . HOH F 5 .   ? -19.735 28.690 41.941  1.00 35.15 ? 306 HOH H O    1 
HETATM 7903 O O    . HOH F 5 .   ? -10.362 38.192 5.804   1.00 33.75 ? 307 HOH H O    1 
HETATM 7904 O O    . HOH F 5 .   ? -10.445 21.948 39.141  1.00 25.14 ? 308 HOH H O    1 
HETATM 7905 O O    . HOH F 5 .   ? -1.456  28.945 3.478   1.00 24.02 ? 309 HOH H O    1 
HETATM 7906 O O    . HOH F 5 .   ? 0.511   37.948 11.147  1.00 27.26 ? 310 HOH H O    1 
HETATM 7907 O O    . HOH F 5 .   ? 11.810  34.973 11.697  1.00 34.10 ? 311 HOH H O    1 
HETATM 7908 O O    . HOH F 5 .   ? -1.298  31.578 -7.941  1.00 29.30 ? 312 HOH H O    1 
HETATM 7909 O O    . HOH F 5 .   ? -5.258  24.587 23.783  1.00 30.04 ? 313 HOH H O    1 
HETATM 7910 O O    . HOH F 5 .   ? -5.599  31.986 11.175  1.00 32.63 ? 314 HOH H O    1 
HETATM 7911 O O    . HOH F 5 .   ? -6.752  43.163 9.050   1.00 33.53 ? 315 HOH H O    1 
HETATM 7912 O O    . HOH F 5 .   ? -12.458 42.763 37.441  1.00 32.58 ? 316 HOH H O    1 
HETATM 7913 O O    . HOH F 5 .   ? -11.116 19.214 33.438  1.00 20.20 ? 317 HOH H O    1 
HETATM 7914 O O    . HOH F 5 .   ? 8.033   45.117 -2.641  1.00 38.52 ? 318 HOH H O    1 
HETATM 7915 O O    . HOH F 5 .   ? 12.412  37.340 -9.203  1.00 26.54 ? 319 HOH H O    1 
HETATM 7916 O O    . HOH F 5 .   ? -5.692  29.664 35.380  1.00 18.17 ? 320 HOH H O    1 
HETATM 7917 O O    . HOH F 5 .   ? 21.580  28.697 -11.119 1.00 25.18 ? 321 HOH H O    1 
HETATM 7918 O O    . HOH F 5 .   ? 8.414   37.550 11.918  1.00 31.87 ? 322 HOH H O    1 
HETATM 7919 O O    . HOH F 5 .   ? -5.726  28.779 30.233  1.00 23.22 ? 323 HOH H O    1 
HETATM 7920 O O    . HOH F 5 .   ? 5.937   23.320 -9.577  1.00 22.90 ? 324 HOH H O    1 
HETATM 7921 O O    . HOH F 5 .   ? 1.813   19.389 1.452   1.00 20.72 ? 325 HOH H O    1 
HETATM 7922 O O    . HOH F 5 .   ? 3.814   25.850 -11.181 1.00 27.34 ? 326 HOH H O    1 
HETATM 7923 O O    . HOH F 5 .   ? 15.302  38.811 7.883   1.00 26.93 ? 327 HOH H O    1 
HETATM 7924 O O    . HOH F 5 .   ? -11.017 35.666 -6.266  1.00 27.35 ? 328 HOH H O    1 
HETATM 7925 O O    . HOH F 5 .   ? 31.350  31.353 2.594   1.00 31.23 ? 329 HOH H O    1 
HETATM 7926 O O    . HOH F 5 .   ? -9.858  36.661 39.253  1.00 19.40 ? 330 HOH H O    1 
HETATM 7927 O O    . HOH F 5 .   ? -0.499  26.179 2.999   1.00 23.21 ? 331 HOH H O    1 
HETATM 7928 O O    . HOH F 5 .   ? -18.914 31.510 40.496  1.00 29.87 ? 332 HOH H O    1 
HETATM 7929 O O    . HOH F 5 .   ? -16.054 27.304 21.805  1.00 21.71 ? 333 HOH H O    1 
HETATM 7930 O O    . HOH F 5 .   ? 5.066   33.498 -10.159 1.00 27.08 ? 334 HOH H O    1 
HETATM 7931 O O    . HOH F 5 .   ? 0.653   27.861 10.902  1.00 26.54 ? 335 HOH H O    1 
HETATM 7932 O O    . HOH F 5 .   ? -7.457  34.744 7.237   1.00 26.06 ? 336 HOH H O    1 
HETATM 7933 O O    . HOH F 5 .   ? -20.020 37.926 20.044  1.00 30.87 ? 337 HOH H O    1 
HETATM 7934 O O    . HOH F 5 .   ? -17.628 30.170 17.741  1.00 25.54 ? 338 HOH H O    1 
HETATM 7935 O O    . HOH F 5 .   ? 11.020  42.063 3.716   1.00 28.34 ? 339 HOH H O    1 
HETATM 7936 O O    . HOH F 5 .   ? 17.241  20.740 9.843   1.00 15.66 ? 340 HOH H O    1 
HETATM 7937 O O    . HOH F 5 .   ? -12.059 27.146 20.068  1.00 25.72 ? 341 HOH H O    1 
HETATM 7938 O O    . HOH F 5 .   ? 9.049   28.655 -13.292 1.00 23.84 ? 342 HOH H O    1 
HETATM 7939 O O    . HOH F 5 .   ? -5.590  21.825 28.460  1.00 28.04 ? 343 HOH H O    1 
HETATM 7940 O O    . HOH F 5 .   ? 3.486   22.641 -3.164  1.00 16.25 ? 344 HOH H O    1 
HETATM 7941 O O    . HOH F 5 .   ? 7.117   42.967 4.829   1.00 28.94 ? 345 HOH H O    1 
HETATM 7942 O O    . HOH F 5 .   ? 4.435   38.095 11.731  1.00 29.15 ? 346 HOH H O    1 
HETATM 7943 O O    . HOH F 5 .   ? -22.053 21.876 33.628  1.00 32.47 ? 347 HOH H O    1 
HETATM 7944 O O    . HOH F 5 .   ? 14.463  41.227 -4.862  1.00 26.97 ? 348 HOH H O    1 
HETATM 7945 O O    . HOH F 5 .   ? 27.311  21.889 2.535   1.00 22.65 ? 349 HOH H O    1 
HETATM 7946 O O    . HOH F 5 .   ? 17.950  40.059 -6.827  1.00 33.98 ? 350 HOH H O    1 
HETATM 7947 O O    . HOH F 5 .   ? -2.480  22.631 38.190  1.00 28.97 ? 351 HOH H O    1 
HETATM 7948 O O    . HOH F 5 .   ? -0.001  24.362 5.010   1.00 17.42 ? 352 HOH H O    1 
HETATM 7949 O O    . HOH F 5 .   ? 11.203  38.719 -4.913  1.00 21.08 ? 353 HOH H O    1 
HETATM 7950 O O    . HOH F 5 .   ? 6.088   36.058 12.705  1.00 33.57 ? 354 HOH H O    1 
HETATM 7951 O O    . HOH F 5 .   ? -16.277 41.328 20.021  1.00 32.98 ? 355 HOH H O    1 
HETATM 7952 O O    . HOH F 5 .   ? 16.220  18.939 -3.902  1.00 12.81 ? 356 HOH H O    1 
HETATM 7953 O O    . HOH F 5 .   ? -5.901  27.522 16.533  1.00 31.40 ? 357 HOH H O    1 
HETATM 7954 O O    . HOH F 5 .   ? -2.343  25.521 -1.321  1.00 27.74 ? 358 HOH H O    1 
HETATM 7955 O O    . HOH F 5 .   ? 20.714  19.267 8.839   1.00 27.12 ? 359 HOH H O    1 
HETATM 7956 O O    . HOH F 5 .   ? -18.886 38.927 35.623  1.00 34.28 ? 360 HOH H O    1 
HETATM 7957 O O    . HOH F 5 .   ? -5.337  29.370 19.254  1.00 25.99 ? 361 HOH H O    1 
HETATM 7958 O O    . HOH F 5 .   ? 25.730  37.004 10.205  1.00 28.29 ? 362 HOH H O    1 
HETATM 7959 O O    . HOH F 5 .   ? 9.688   34.616 -11.440 1.00 20.42 ? 363 HOH H O    1 
HETATM 7960 O O    . HOH F 5 .   ? 18.496  43.148 -2.628  1.00 32.63 ? 364 HOH H O    1 
HETATM 7961 O O    . HOH F 5 .   ? -19.518 40.237 16.696  1.00 38.28 ? 365 HOH H O    1 
HETATM 7962 O O    . HOH F 5 .   ? -5.754  26.460 8.226   1.00 31.53 ? 366 HOH H O    1 
HETATM 7963 O O    . HOH F 5 .   ? -4.651  29.670 6.010   1.00 23.31 ? 367 HOH H O    1 
HETATM 7964 O O    . HOH F 5 .   ? -3.259  38.720 23.986  1.00 28.28 ? 368 HOH H O    1 
HETATM 7965 O O    . HOH F 5 .   ? 26.742  24.478 -5.478  1.00 20.54 ? 369 HOH H O    1 
HETATM 7966 O O    . HOH F 5 .   ? -1.318  42.734 -4.838  1.00 23.84 ? 370 HOH H O    1 
HETATM 7967 O O    . HOH F 5 .   ? -1.350  29.720 37.061  1.00 26.20 ? 371 HOH H O    1 
HETATM 7968 O O    . HOH F 5 .   ? -12.680 33.659 42.602  1.00 28.27 ? 372 HOH H O    1 
HETATM 7969 O O    . HOH F 5 .   ? 25.776  34.200 -7.793  1.00 31.27 ? 373 HOH H O    1 
HETATM 7970 O O    . HOH F 5 .   ? -5.892  28.877 23.318  1.00 22.19 ? 374 HOH H O    1 
HETATM 7971 O O    . HOH F 5 .   ? -5.596  36.113 30.691  1.00 25.34 ? 375 HOH H O    1 
HETATM 7972 O O    . HOH F 5 .   ? 29.022  27.857 9.848   1.00 32.04 ? 376 HOH H O    1 
HETATM 7973 O O    . HOH F 5 .   ? -13.691 42.987 11.832  1.00 28.04 ? 377 HOH H O    1 
HETATM 7974 O O    . HOH F 5 .   ? 14.777  26.739 12.927  1.00 30.81 ? 378 HOH H O    1 
HETATM 7975 O O    . HOH F 5 .   ? 2.450   22.700 -7.878  1.00 22.40 ? 379 HOH H O    1 
HETATM 7976 O O    . HOH F 5 .   ? -9.378  35.937 0.490   1.00 31.05 ? 380 HOH H O    1 
HETATM 7977 O O    . HOH F 5 .   ? -3.227  31.428 31.786  1.00 29.58 ? 381 HOH H O    1 
HETATM 7978 O O    . HOH F 5 .   ? -10.154 46.406 28.967  1.00 29.11 ? 382 HOH H O    1 
HETATM 7979 O O    . HOH F 5 .   ? 14.986  30.496 -16.156 1.00 29.33 ? 383 HOH H O    1 
HETATM 7980 O O    . HOH F 5 .   ? 18.672  29.567 11.693  1.00 29.47 ? 384 HOH H O    1 
HETATM 7981 O O    . HOH F 5 .   ? -4.495  36.176 13.990  1.00 27.23 ? 385 HOH H O    1 
HETATM 7982 O O    . HOH F 5 .   ? 25.195  20.271 1.885   1.00 22.62 ? 386 HOH H O    1 
HETATM 7983 O O    . HOH F 5 .   ? 21.695  23.322 -3.032  1.00 13.21 ? 387 HOH H O    1 
HETATM 7984 O O    . HOH F 5 .   ? 23.183  35.427 -12.001 1.00 31.63 ? 388 HOH H O    1 
HETATM 7985 O O    . HOH F 5 .   ? -5.348  24.510 28.527  1.00 23.90 ? 389 HOH H O    1 
HETATM 7986 O O    . HOH F 5 .   ? 25.778  31.030 -7.723  1.00 30.16 ? 390 HOH H O    1 
HETATM 7987 O O    . HOH F 5 .   ? 0.559   43.553 11.197  1.00 37.40 ? 391 HOH H O    1 
HETATM 7988 O O    . HOH F 5 .   ? -12.296 24.503 43.026  1.00 30.06 ? 392 HOH H O    1 
HETATM 7989 O O    . HOH F 5 .   ? -1.415  36.792 15.474  1.00 34.77 ? 393 HOH H O    1 
HETATM 7990 O O    . HOH F 5 .   ? -9.787  28.944 43.169  1.00 30.00 ? 394 HOH H O    1 
HETATM 7991 O O    . HOH F 5 .   ? 7.847   26.356 -11.751 1.00 21.36 ? 395 HOH H O    1 
HETATM 7992 O O    . HOH F 5 .   ? 27.322  24.597 5.352   1.00 27.57 ? 396 HOH H O    1 
HETATM 7993 O O    . HOH F 5 .   ? 0.113   24.043 -5.856  1.00 23.76 ? 397 HOH H O    1 
HETATM 7994 O O    . HOH F 5 .   ? -14.066 43.012 33.391  1.00 26.78 ? 398 HOH H O    1 
HETATM 7995 O O    . HOH F 5 .   ? -4.113  25.046 33.786  1.00 30.44 ? 399 HOH H O    1 
HETATM 7996 O O    . HOH F 5 .   ? -7.151  35.656 10.023  1.00 22.34 ? 400 HOH H O    1 
HETATM 7997 O O    . HOH F 5 .   ? 9.058   40.494 10.860  1.00 37.39 ? 401 HOH H O    1 
HETATM 7998 O O    . HOH F 5 .   ? 6.153   44.270 2.539   1.00 31.53 ? 402 HOH H O    1 
HETATM 7999 O O    . HOH F 5 .   ? 8.093   27.882 13.890  1.00 23.84 ? 403 HOH H O    1 
HETATM 8000 O O    . HOH F 5 .   ? 16.991  36.651 -8.128  1.00 18.07 ? 404 HOH H O    1 
HETATM 8001 O O    . HOH F 5 .   ? -5.870  24.627 40.807  1.00 22.45 ? 405 HOH H O    1 
HETATM 8002 O O    . HOH F 5 .   ? -5.045  31.876 22.045  1.00 35.32 ? 406 HOH H O    1 
HETATM 8003 O O    . HOH F 5 .   ? 0.302   22.793 12.160  1.00 28.27 ? 407 HOH H O    1 
HETATM 8004 O O    . HOH F 5 .   ? 26.818  22.435 5.528   1.00 29.82 ? 408 HOH H O    1 
HETATM 8005 O O    . HOH F 5 .   ? -4.589  30.930 27.710  1.00 22.08 ? 409 HOH H O    1 
HETATM 8006 O O    . HOH F 5 .   ? 12.678  31.033 -14.010 1.00 21.59 ? 410 HOH H O    1 
HETATM 8007 O O    . HOH F 5 .   ? -7.333  32.150 6.664   1.00 28.73 ? 411 HOH H O    1 
HETATM 8008 O O    . HOH F 5 .   ? -21.643 30.823 26.355  1.00 23.38 ? 412 HOH H O    1 
HETATM 8009 O O    . HOH F 5 .   ? -15.344 28.644 20.206  1.00 31.33 ? 413 HOH H O    1 
HETATM 8010 O O    . HOH F 5 .   ? 29.107  26.121 6.206   1.00 31.49 ? 414 HOH H O    1 
HETATM 8011 O O    . HOH F 5 .   ? 28.259  34.168 6.660   1.00 37.92 ? 415 HOH H O    1 
HETATM 8012 O O    . HOH F 5 .   ? -2.557  29.234 -2.795  1.00 34.66 ? 416 HOH H O    1 
HETATM 8013 O O    . HOH F 5 .   ? -2.180  32.682 24.243  1.00 31.57 ? 417 HOH H O    1 
HETATM 8014 O O    . HOH F 5 .   ? -0.217  46.318 -1.552  1.00 31.22 ? 418 HOH H O    1 
HETATM 8015 O O    . HOH F 5 .   ? -4.693  19.951 28.793  1.00 33.18 ? 419 HOH H O    1 
HETATM 8016 O O    . HOH F 5 .   ? 6.302   40.343 -8.010  1.00 34.08 ? 420 HOH H O    1 
HETATM 8017 O O    . HOH F 5 .   ? -4.095  26.224 26.716  1.00 33.85 ? 421 HOH H O    1 
HETATM 8018 O O    . HOH F 5 .   ? 27.671  33.668 -1.776  1.00 32.19 ? 422 HOH H O    1 
HETATM 8019 O O    . HOH F 5 .   ? 23.038  17.555 1.800   1.00 22.94 ? 423 HOH H O    1 
HETATM 8020 O O    . HOH F 5 .   ? 16.212  23.239 10.637  1.00 27.71 ? 424 HOH H O    1 
HETATM 8021 O O    . HOH F 5 .   ? 22.310  37.831 -7.174  1.00 36.09 ? 425 HOH H O    1 
HETATM 8022 O O    . HOH F 5 .   ? 19.644  36.936 -8.757  1.00 30.15 ? 426 HOH H O    1 
HETATM 8023 O O    . HOH F 5 .   ? -7.041  18.061 33.066  1.00 31.47 ? 427 HOH H O    1 
HETATM 8024 O O    . HOH F 5 .   ? -22.093 20.085 35.238  1.00 35.91 ? 428 HOH H O    1 
HETATM 8025 O O    . HOH F 5 .   ? -15.460 41.129 10.770  1.00 30.97 ? 429 HOH H O    1 
HETATM 8026 O O    . HOH F 5 .   ? 15.246  37.725 -9.898  1.00 27.55 ? 430 HOH H O    1 
HETATM 8027 O O    . HOH F 5 .   ? -10.568 39.241 38.986  1.00 29.59 ? 431 HOH H O    1 
HETATM 8028 O O    . HOH F 5 .   ? -6.136  29.940 12.933  1.00 34.38 ? 432 HOH H O    1 
HETATM 8029 O O    . HOH F 5 .   ? -2.633  23.599 41.940  1.00 33.76 ? 433 HOH H O    1 
HETATM 8030 O O    . HOH F 5 .   ? 1.053   32.081 -14.160 1.00 39.47 ? 434 HOH H O    1 
HETATM 8031 O O    . HOH F 5 .   ? -13.180 40.329 38.891  1.00 27.92 ? 435 HOH H O    1 
HETATM 8032 O O    . HOH F 5 .   ? -10.035 35.794 7.224   1.00 30.71 ? 436 HOH H O    1 
HETATM 8033 O O    . HOH F 5 .   ? -3.875  28.489 28.713  1.00 32.31 ? 437 HOH H O    1 
HETATM 8034 O O    . HOH F 5 .   ? 5.726   25.511 -13.107 1.00 34.45 ? 438 HOH H O    1 
HETATM 8035 O O    . HOH F 5 .   ? -0.358  18.214 4.208   1.00 30.63 ? 439 HOH H O    1 
HETATM 8036 O O    . HOH F 5 .   ? -4.976  28.174 33.130  1.00 28.61 ? 440 HOH H O    1 
HETATM 8037 O O    . HOH F 5 .   ? -7.683  27.872 11.908  1.00 31.92 ? 441 HOH H O    1 
HETATM 8038 O O    . HOH F 5 .   ? 9.145   39.188 -12.152 1.00 33.81 ? 442 HOH H O    1 
HETATM 8039 O O    . HOH F 5 .   ? -8.078  23.780 42.361  1.00 29.10 ? 443 HOH H O    1 
HETATM 8040 O O    . HOH F 5 .   ? 10.241  32.861 -13.523 1.00 25.71 ? 444 HOH H O    1 
HETATM 8041 O O    . HOH F 5 .   ? 29.430  38.204 5.192   1.00 32.39 ? 445 HOH H O    1 
HETATM 8042 O O    . HOH F 5 .   ? -5.996  30.725 8.664   1.00 26.73 ? 446 HOH H O    1 
HETATM 8043 O O    . HOH F 5 .   ? -0.396  20.717 0.646   1.00 30.79 ? 447 HOH H O    1 
HETATM 8044 O O    . HOH F 5 .   ? 3.144   19.523 -11.067 1.00 36.39 ? 448 HOH H O    1 
HETATM 8045 O O    . HOH F 5 .   ? -7.171  28.623 9.159   1.00 29.69 ? 449 HOH H O    1 
HETATM 8046 O O    . HOH F 5 .   ? 10.967  36.925 -11.688 1.00 28.40 ? 450 HOH H O    1 
HETATM 8047 O O    . HOH F 5 .   ? -10.597 22.770 41.739  1.00 28.80 ? 451 HOH H O    1 
HETATM 8048 O O    . HOH F 5 .   ? -9.613  30.858 6.035   1.00 30.82 ? 452 HOH H O    1 
HETATM 8049 O O    . HOH F 5 .   ? 2.938   21.536 -5.684  1.00 23.08 ? 453 HOH H O    1 
HETATM 8050 O O    . HOH F 5 .   ? -1.873  26.071 -14.038 1.00 37.71 ? 454 HOH H O    1 
HETATM 8051 O O    . HOH G 5 .   ? 6.707   0.812  6.341   1.00 32.46 ? 301 HOH L O    1 
HETATM 8052 O O    . HOH G 5 .   ? -22.983 20.769 12.786  1.00 30.66 ? 302 HOH L O    1 
HETATM 8053 O O    . HOH G 5 .   ? 17.567  6.562  27.101  1.00 31.68 ? 303 HOH L O    1 
HETATM 8054 O O    . HOH G 5 .   ? -20.388 30.399 18.058  1.00 24.90 ? 304 HOH L O    1 
HETATM 8055 O O    . HOH G 5 .   ? 3.751   1.509  12.200  1.00 29.16 ? 305 HOH L O    1 
HETATM 8056 O O    . HOH G 5 .   ? 11.623  10.254 -3.799  1.00 18.06 ? 306 HOH L O    1 
HETATM 8057 O O    . HOH G 5 .   ? -18.798 18.411 16.149  1.00 30.59 ? 307 HOH L O    1 
HETATM 8058 O O    . HOH G 5 .   ? 7.114   16.852 -10.810 1.00 22.77 ? 308 HOH L O    1 
HETATM 8059 O O    . HOH G 5 .   ? 1.449   17.392 25.255  1.00 33.08 ? 309 HOH L O    1 
HETATM 8060 O O    . HOH G 5 .   ? 10.816  -0.253 11.803  1.00 24.85 ? 310 HOH L O    1 
HETATM 8061 O O    . HOH G 5 .   ? 16.922  3.168  -1.331  1.00 26.28 ? 311 HOH L O    1 
HETATM 8062 O O    . HOH G 5 .   ? 0.597   8.664  29.912  1.00 36.46 ? 312 HOH L O    1 
HETATM 8063 O O    . HOH G 5 .   ? 15.931  1.029  9.998   1.00 29.58 ? 313 HOH L O    1 
HETATM 8064 O O    . HOH G 5 .   ? -5.134  7.978  17.462  1.00 25.61 ? 314 HOH L O    1 
HETATM 8065 O O    . HOH G 5 .   ? -4.644  21.456 19.478  1.00 26.78 ? 315 HOH L O    1 
HETATM 8066 O O    . HOH G 5 .   ? 19.428  4.838  8.685   1.00 22.41 ? 316 HOH L O    1 
HETATM 8067 O O    . HOH G 5 .   ? -15.805 24.426 19.481  1.00 21.11 ? 317 HOH L O    1 
HETATM 8068 O O    . HOH G 5 .   ? -17.144 14.979 15.044  1.00 32.09 ? 318 HOH L O    1 
HETATM 8069 O O    . HOH G 5 .   ? 3.293   19.766 12.580  1.00 22.71 ? 319 HOH L O    1 
HETATM 8070 O O    . HOH G 5 .   ? -5.937  16.084 17.582  1.00 32.59 ? 320 HOH L O    1 
HETATM 8071 O O    . HOH G 5 .   ? -2.439  2.863  19.566  1.00 36.23 ? 321 HOH L O    1 
HETATM 8072 O O    . HOH G 5 .   ? 12.519  12.688 -8.704  1.00 17.04 ? 322 HOH L O    1 
HETATM 8073 O O    . HOH G 5 .   ? 16.052  17.829 24.022  1.00 28.89 ? 323 HOH L O    1 
HETATM 8074 O O    . HOH G 5 .   ? -11.833 17.607 15.407  1.00 34.08 ? 324 HOH L O    1 
HETATM 8075 O O    . HOH G 5 .   ? -12.698 6.773  19.687  1.00 25.10 ? 325 HOH L O    1 
HETATM 8076 O O    . HOH G 5 .   ? -24.391 28.774 29.295  1.00 31.33 ? 326 HOH L O    1 
HETATM 8077 O O    . HOH G 5 .   ? 18.638  1.251  6.528   1.00 31.89 ? 327 HOH L O    1 
HETATM 8078 O O    . HOH G 5 .   ? 9.314   0.650  26.871  1.00 20.90 ? 328 HOH L O    1 
HETATM 8079 O O    . HOH G 5 .   ? 1.135   8.373  -2.440  1.00 25.31 ? 329 HOH L O    1 
HETATM 8080 O O    . HOH G 5 .   ? -23.439 32.491 25.347  1.00 22.30 ? 330 HOH L O    1 
HETATM 8081 O O    . HOH G 5 .   ? 19.118  18.251 11.254  1.00 27.30 ? 331 HOH L O    1 
HETATM 8082 O O    . HOH G 5 .   ? 20.149  12.583 -1.182  1.00 16.19 ? 332 HOH L O    1 
HETATM 8083 O O    . HOH G 5 .   ? 0.813   5.879  29.555  1.00 34.37 ? 333 HOH L O    1 
HETATM 8084 O O    . HOH G 5 .   ? -19.705 22.241 10.412  1.00 30.57 ? 334 HOH L O    1 
HETATM 8085 O O    . HOH G 5 .   ? -3.102  5.863  17.183  1.00 23.49 ? 335 HOH L O    1 
HETATM 8086 O O    . HOH G 5 .   ? 2.312   18.296 4.653   1.00 19.06 ? 336 HOH L O    1 
HETATM 8087 O O    . HOH G 5 .   ? -5.521  2.771  24.722  1.00 18.48 ? 337 HOH L O    1 
HETATM 8088 O O    . HOH G 5 .   ? 26.056  11.472 3.087   1.00 35.41 ? 338 HOH L O    1 
HETATM 8089 O O    . HOH G 5 .   ? 2.988   3.897  -5.024  1.00 38.07 ? 339 HOH L O    1 
HETATM 8090 O O    . HOH G 5 .   ? 16.728  5.573  22.871  1.00 17.59 ? 340 HOH L O    1 
HETATM 8091 O O    . HOH G 5 .   ? 18.973  2.909  15.126  1.00 28.64 ? 341 HOH L O    1 
HETATM 8092 O O    . HOH G 5 .   ? -1.390  3.646  14.787  1.00 24.01 ? 342 HOH L O    1 
HETATM 8093 O O    . HOH G 5 .   ? 5.918   17.553 20.253  1.00 26.02 ? 343 HOH L O    1 
HETATM 8094 O O    . HOH G 5 .   ? 11.624  12.185 -6.133  1.00 18.34 ? 344 HOH L O    1 
HETATM 8095 O O    . HOH G 5 .   ? -19.797 27.186 15.241  1.00 25.80 ? 345 HOH L O    1 
HETATM 8096 O O    . HOH G 5 .   ? 19.656  11.594 22.017  1.00 30.13 ? 346 HOH L O    1 
HETATM 8097 O O    . HOH G 5 .   ? 10.542  11.150 -12.061 1.00 25.47 ? 347 HOH L O    1 
HETATM 8098 O O    . HOH G 5 .   ? 10.177  17.556 23.229  1.00 23.84 ? 348 HOH L O    1 
HETATM 8099 O O    . HOH G 5 .   ? -9.711  1.682  30.197  1.00 27.83 ? 349 HOH L O    1 
HETATM 8100 O O    . HOH G 5 .   ? 7.138   22.520 21.320  1.00 32.43 ? 350 HOH L O    1 
HETATM 8101 O O    . HOH G 5 .   ? 13.993  13.985 19.085  1.00 13.81 ? 351 HOH L O    1 
HETATM 8102 O O    . HOH G 5 .   ? 8.114   23.119 -10.918 1.00 27.36 ? 352 HOH L O    1 
HETATM 8103 O O    . HOH G 5 .   ? 16.402  2.987  14.317  1.00 19.78 ? 353 HOH L O    1 
HETATM 8104 O O    . HOH G 5 .   ? -2.761  10.101 -0.721  1.00 35.83 ? 354 HOH L O    1 
HETATM 8105 O O    . HOH G 5 .   ? 12.896  -1.857 13.003  1.00 28.24 ? 355 HOH L O    1 
HETATM 8106 O O    . HOH G 5 .   ? 12.227  6.003  -6.133  1.00 26.20 ? 356 HOH L O    1 
HETATM 8107 O O    . HOH G 5 .   ? 6.255   -0.630 19.110  1.00 20.74 ? 357 HOH L O    1 
HETATM 8108 O O    . HOH G 5 .   ? -4.791  11.113 16.677  1.00 31.12 ? 358 HOH L O    1 
HETATM 8109 O O    . HOH G 5 .   ? 13.315  6.245  4.569   1.00 15.42 ? 359 HOH L O    1 
HETATM 8110 O O    . HOH G 5 .   ? 1.427   13.271 28.610  1.00 27.71 ? 360 HOH L O    1 
HETATM 8111 O O    . HOH G 5 .   ? 12.547  19.233 16.197  1.00 23.21 ? 361 HOH L O    1 
HETATM 8112 O O    . HOH G 5 .   ? -5.547  18.066 27.099  1.00 16.26 ? 362 HOH L O    1 
HETATM 8113 O O    . HOH G 5 .   ? 6.375   16.343 -7.740  1.00 21.14 ? 363 HOH L O    1 
HETATM 8114 O O    . HOH G 5 .   ? 4.785   8.241  8.310   1.00 15.22 ? 364 HOH L O    1 
HETATM 8115 O O    . HOH G 5 .   ? 13.452  -0.458 25.331  1.00 24.79 ? 365 HOH L O    1 
HETATM 8116 O O    . HOH G 5 .   ? -14.415 21.838 13.127  1.00 33.20 ? 366 HOH L O    1 
HETATM 8117 O O    . HOH G 5 .   ? -13.431 5.401  30.811  1.00 30.00 ? 367 HOH L O    1 
HETATM 8118 O O    . HOH G 5 .   ? -32.126 27.515 27.746  1.00 23.84 ? 368 HOH L O    1 
HETATM 8119 O O    . HOH G 5 .   ? -22.958 28.384 25.267  1.00 21.93 ? 369 HOH L O    1 
HETATM 8120 O O    . HOH G 5 .   ? 1.913   4.951  3.778   1.00 24.68 ? 370 HOH L O    1 
HETATM 8121 O O    . HOH G 5 .   ? -18.017 29.488 11.852  1.00 33.49 ? 371 HOH L O    1 
HETATM 8122 O O    . HOH G 5 .   ? 7.046   -0.979 14.824  1.00 29.35 ? 372 HOH L O    1 
HETATM 8123 O O    . HOH G 5 .   ? 13.478  23.382 14.653  1.00 29.15 ? 373 HOH L O    1 
HETATM 8124 O O    . HOH G 5 .   ? -4.426  17.459 19.767  1.00 23.04 ? 374 HOH L O    1 
HETATM 8125 O O    . HOH G 5 .   ? -13.172 14.663 16.625  1.00 26.72 ? 375 HOH L O    1 
HETATM 8126 O O    . HOH G 5 .   ? 0.206   17.808 10.055  1.00 30.33 ? 376 HOH L O    1 
HETATM 8127 O O    . HOH G 5 .   ? -18.257 20.153 13.512  1.00 36.10 ? 377 HOH L O    1 
HETATM 8128 O O    . HOH G 5 .   ? 0.709   16.592 1.845   1.00 32.21 ? 378 HOH L O    1 
HETATM 8129 O O    . HOH G 5 .   ? 14.444  16.411 20.603  1.00 21.34 ? 379 HOH L O    1 
HETATM 8130 O O    . HOH G 5 .   ? 7.667   3.440  28.975  1.00 21.81 ? 380 HOH L O    1 
HETATM 8131 O O    . HOH G 5 .   ? 13.707  2.164  8.933   1.00 24.41 ? 381 HOH L O    1 
HETATM 8132 O O    . HOH G 5 .   ? 2.232   14.627 -1.191  1.00 21.64 ? 382 HOH L O    1 
HETATM 8133 O O    . HOH G 5 .   ? -23.479 17.929 13.612  1.00 36.28 ? 383 HOH L O    1 
HETATM 8134 O O    . HOH G 5 .   ? 2.736   14.158 19.995  1.00 18.90 ? 384 HOH L O    1 
HETATM 8135 O O    . HOH G 5 .   ? 15.011  3.755  -4.940  1.00 22.72 ? 385 HOH L O    1 
HETATM 8136 O O    . HOH G 5 .   ? -13.645 26.101 21.973  1.00 19.90 ? 386 HOH L O    1 
HETATM 8137 O O    . HOH G 5 .   ? -20.707 12.212 30.345  1.00 28.58 ? 387 HOH L O    1 
HETATM 8138 O O    . HOH G 5 .   ? -5.375  8.827  19.851  1.00 24.84 ? 388 HOH L O    1 
HETATM 8139 O O    . HOH G 5 .   ? -2.571  12.468 13.058  1.00 33.04 ? 389 HOH L O    1 
HETATM 8140 O O    . HOH G 5 .   ? 4.684   20.842 -1.427  1.00 11.49 ? 390 HOH L O    1 
HETATM 8141 O O    . HOH G 5 .   ? 8.363   15.438 22.960  1.00 22.27 ? 391 HOH L O    1 
HETATM 8142 O O    . HOH G 5 .   ? -0.871  16.341 21.522  1.00 20.01 ? 392 HOH L O    1 
HETATM 8143 O O    . HOH G 5 .   ? 1.064   14.398 22.047  1.00 24.84 ? 393 HOH L O    1 
HETATM 8144 O O    . HOH G 5 .   ? -7.419  16.531 28.360  1.00 15.48 ? 394 HOH L O    1 
HETATM 8145 O O    . HOH G 5 .   ? -19.288 4.917  21.317  1.00 32.02 ? 395 HOH L O    1 
HETATM 8146 O O    . HOH G 5 .   ? -3.898  12.283 18.537  1.00 28.12 ? 396 HOH L O    1 
HETATM 8147 O O    . HOH G 5 .   ? 6.815   3.727  -10.100 1.00 36.01 ? 397 HOH L O    1 
HETATM 8148 O O    . HOH G 5 .   ? -37.856 32.906 15.495  1.00 38.82 ? 398 HOH L O    1 
HETATM 8149 O O    . HOH G 5 .   ? 10.685  20.999 15.611  1.00 17.64 ? 399 HOH L O    1 
HETATM 8150 O O    . HOH G 5 .   ? -3.723  22.386 24.297  1.00 23.24 ? 400 HOH L O    1 
HETATM 8151 O O    . HOH G 5 .   ? -0.830  19.888 29.455  1.00 31.04 ? 401 HOH L O    1 
HETATM 8152 O O    . HOH G 5 .   ? -17.534 28.130 16.157  1.00 30.07 ? 402 HOH L O    1 
HETATM 8153 O O    . HOH G 5 .   ? -1.608  12.929 10.780  1.00 29.38 ? 403 HOH L O    1 
HETATM 8154 O O    . HOH G 5 .   ? -0.604  3.280  17.364  1.00 21.53 ? 404 HOH L O    1 
HETATM 8155 O O    . HOH G 5 .   ? -4.345  16.925 34.170  1.00 33.52 ? 405 HOH L O    1 
HETATM 8156 O O    . HOH G 5 .   ? -32.766 16.917 19.561  1.00 37.38 ? 406 HOH L O    1 
HETATM 8157 O O    . HOH G 5 .   ? 3.224   18.601 -0.586  1.00 15.64 ? 407 HOH L O    1 
HETATM 8158 O O    . HOH G 5 .   ? -11.169 4.681  18.626  1.00 32.41 ? 408 HOH L O    1 
HETATM 8159 O O    . HOH G 5 .   ? 4.035   1.898  9.959   1.00 32.26 ? 409 HOH L O    1 
HETATM 8160 O O    . HOH G 5 .   ? 20.327  4.809  -7.738  1.00 25.82 ? 410 HOH L O    1 
HETATM 8161 O O    . HOH G 5 .   ? -2.583  4.725  31.047  1.00 27.45 ? 411 HOH L O    1 
HETATM 8162 O O    . HOH G 5 .   ? 19.414  6.693  -3.613  1.00 23.14 ? 412 HOH L O    1 
HETATM 8163 O O    . HOH G 5 .   ? 6.929   -0.479 27.269  1.00 16.74 ? 413 HOH L O    1 
HETATM 8164 O O    . HOH G 5 .   ? 19.968  7.529  19.985  1.00 25.90 ? 414 HOH L O    1 
HETATM 8165 O O    . HOH G 5 .   ? 4.169   19.801 15.921  1.00 29.37 ? 415 HOH L O    1 
HETATM 8166 O O    . HOH G 5 .   ? -27.245 33.716 31.102  1.00 33.05 ? 416 HOH L O    1 
HETATM 8167 O O    . HOH G 5 .   ? 13.045  6.116  26.837  1.00 26.51 ? 417 HOH L O    1 
HETATM 8168 O O    . HOH G 5 .   ? -29.301 11.210 20.568  1.00 46.21 ? 418 HOH L O    1 
HETATM 8169 O O    . HOH G 5 .   ? -24.412 18.887 30.755  1.00 27.67 ? 419 HOH L O    1 
HETATM 8170 O O    . HOH G 5 .   ? -8.178  22.325 17.459  1.00 28.01 ? 420 HOH L O    1 
HETATM 8171 O O    . HOH G 5 .   ? -22.315 36.174 19.636  1.00 27.32 ? 421 HOH L O    1 
HETATM 8172 O O    . HOH G 5 .   ? 5.563   1.471  15.791  1.00 17.82 ? 422 HOH L O    1 
HETATM 8173 O O    . HOH G 5 .   ? -15.008 12.614 13.739  1.00 43.17 ? 423 HOH L O    1 
HETATM 8174 O O    . HOH G 5 .   ? -4.083  6.743  12.911  1.00 22.06 ? 424 HOH L O    1 
HETATM 8175 O O    . HOH G 5 .   ? 24.245  11.860 13.028  1.00 34.00 ? 425 HOH L O    1 
HETATM 8176 O O    . HOH G 5 .   ? 22.575  17.682 7.840   1.00 33.52 ? 426 HOH L O    1 
HETATM 8177 O O    . HOH G 5 .   ? -31.190 36.749 15.207  1.00 38.38 ? 427 HOH L O    1 
HETATM 8178 O O    . HOH G 5 .   ? 8.308   -1.909 20.752  1.00 16.25 ? 428 HOH L O    1 
HETATM 8179 O O    . HOH G 5 .   ? 9.045   -0.211 -3.800  1.00 31.95 ? 429 HOH L O    1 
HETATM 8180 O O    . HOH G 5 .   ? -32.994 21.354 30.159  1.00 23.84 ? 430 HOH L O    1 
HETATM 8181 O O    . HOH G 5 .   ? -9.904  10.443 32.369  1.00 36.03 ? 431 HOH L O    1 
HETATM 8182 O O    . HOH G 5 .   ? -26.272 35.610 30.775  1.00 30.98 ? 432 HOH L O    1 
HETATM 8183 O O    . HOH G 5 .   ? 19.586  2.363  17.603  1.00 35.65 ? 433 HOH L O    1 
HETATM 8184 O O    . HOH G 5 .   ? -4.563  4.702  20.678  1.00 19.76 ? 434 HOH L O    1 
HETATM 8185 O O    . HOH G 5 .   ? -6.219  5.345  18.494  1.00 23.26 ? 435 HOH L O    1 
HETATM 8186 O O    . HOH G 5 .   ? -20.465 27.215 12.640  1.00 32.91 ? 436 HOH L O    1 
HETATM 8187 O O    . HOH G 5 .   ? -2.724  12.099 2.928   1.00 32.86 ? 437 HOH L O    1 
HETATM 8188 O O    . HOH G 5 .   ? 17.477  2.569  2.412   1.00 33.89 ? 438 HOH L O    1 
HETATM 8189 O O    . HOH G 5 .   ? -2.044  17.483 17.404  1.00 41.60 ? 439 HOH L O    1 
HETATM 8190 O O    . HOH G 5 .   ? 13.937  3.774  -7.584  1.00 30.67 ? 440 HOH L O    1 
HETATM 8191 O O    . HOH G 5 .   ? 1.691   19.270 -5.320  1.00 37.11 ? 441 HOH L O    1 
HETATM 8192 O O    . HOH G 5 .   ? -19.073 26.292 10.317  1.00 35.81 ? 442 HOH L O    1 
HETATM 8193 O O    . HOH G 5 .   ? 15.925  16.186 16.852  1.00 23.84 ? 443 HOH L O    1 
HETATM 8194 O O    . HOH G 5 .   ? -3.461  11.138 8.235   1.00 33.35 ? 444 HOH L O    1 
HETATM 8195 O O    . HOH G 5 .   ? -11.921 12.439 15.320  1.00 35.49 ? 445 HOH L O    1 
HETATM 8196 O O    . HOH G 5 .   ? -4.000  5.177  10.348  1.00 30.75 ? 446 HOH L O    1 
HETATM 8197 O O    . HOH G 5 .   ? 9.144   21.371 22.373  1.00 36.19 ? 447 HOH L O    1 
HETATM 8198 O O    . HOH G 5 .   ? 19.494  8.354  24.324  1.00 37.49 ? 448 HOH L O    1 
HETATM 8199 O O    . HOH G 5 .   ? 12.625  8.116  -13.309 1.00 27.90 ? 449 HOH L O    1 
HETATM 8200 O O    . HOH G 5 .   ? 12.317  -5.003 15.981  1.00 39.56 ? 450 HOH L O    1 
HETATM 8201 O O    . HOH G 5 .   ? -5.346  22.085 17.460  1.00 37.37 ? 451 HOH L O    1 
HETATM 8202 O O    . HOH G 5 .   ? -1.370  1.995  27.673  1.00 31.53 ? 452 HOH L O    1 
HETATM 8203 O O    . HOH G 5 .   ? -4.512  15.106 35.814  1.00 37.19 ? 453 HOH L O    1 
HETATM 8204 O O    . HOH G 5 .   ? -27.712 37.845 31.664  1.00 31.81 ? 454 HOH L O    1 
HETATM 8205 O O    . HOH G 5 .   ? 18.162  15.483 19.733  1.00 39.93 ? 455 HOH L O    1 
HETATM 8206 O O    . HOH G 5 .   ? 3.114   16.556 19.041  1.00 28.98 ? 456 HOH L O    1 
HETATM 8207 O O    . HOH G 5 .   ? -8.477  3.647  18.532  1.00 25.05 ? 457 HOH L O    1 
HETATM 8208 O O    . HOH G 5 .   ? 1.509   17.883 -2.641  1.00 27.42 ? 458 HOH L O    1 
HETATM 8209 O O    . HOH G 5 .   ? 3.270   2.691  3.260   1.00 33.68 ? 459 HOH L O    1 
HETATM 8210 O O    . HOH G 5 .   ? 16.537  14.116 18.195  1.00 23.84 ? 460 HOH L O    1 
HETATM 8211 O O    . HOH G 5 .   ? -7.843  0.228  31.286  1.00 32.34 ? 461 HOH L O    1 
HETATM 8212 O O    . HOH G 5 .   ? 1.063   0.800  17.406  1.00 28.29 ? 462 HOH L O    1 
HETATM 8213 O O    . HOH G 5 .   ? 17.324  2.175  -5.095  1.00 30.32 ? 463 HOH L O    1 
HETATM 8214 O O    . HOH G 5 .   ? -0.501  1.460  10.565  1.00 30.68 ? 464 HOH L O    1 
HETATM 8215 O O    . HOH G 5 .   ? 12.190  5.148  28.891  1.00 32.44 ? 465 HOH L O    1 
HETATM 8216 O O    . HOH G 5 .   ? 19.296  4.091  -5.081  1.00 27.31 ? 466 HOH L O    1 
HETATM 8217 O O    . HOH G 5 .   ? 10.389  -1.702 9.515   1.00 36.19 ? 467 HOH L O    1 
HETATM 8218 O O    . HOH G 5 .   ? -6.464  3.221  22.303  1.00 20.92 ? 468 HOH L O    1 
HETATM 8219 O O    . HOH G 5 .   ? -0.622  2.020  29.806  1.00 36.20 ? 469 HOH L O    1 
HETATM 8220 O O    . HOH G 5 .   ? -4.966  4.222  16.739  1.00 23.36 ? 470 HOH L O    1 
HETATM 8221 O O    . HOH G 5 .   ? -24.188 36.775 31.356  1.00 34.50 ? 471 HOH L O    1 
HETATM 8222 O O    . HOH G 5 .   ? 6.349   1.149  29.484  1.00 20.47 ? 472 HOH L O    1 
HETATM 8223 O O    . HOH G 5 .   ? -23.151 17.090 34.090  1.00 31.38 ? 473 HOH L O    1 
HETATM 8224 O O    . HOH G 5 .   ? 21.926  10.684 -0.850  1.00 22.12 ? 474 HOH L O    1 
HETATM 8225 O O    . HOH G 5 .   ? 7.216   10.432 28.264  1.00 33.06 ? 475 HOH L O    1 
HETATM 8226 O O    . HOH G 5 .   ? -0.344  1.778  13.260  1.00 27.91 ? 476 HOH L O    1 
HETATM 8227 O O    . HOH G 5 .   ? 3.170   0.179  15.849  1.00 28.53 ? 477 HOH L O    1 
# 
