data_9DMY
# 
_entry.id   9DMY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DMY         pdb_00009dmy 10.2210/pdb9dmy/pdb 
WWPDB D_1000287935 ?            ?                   
EMDB  EMD-47020    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Data collection' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            em_admin 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_em_admin.last_update' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DMY 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'chronic wasting disease prion fibril'              EMD-47020 'associated EM volume' 
EMDB 'glycosylated chronic wasting disease prion fibril' EMD-47021 'other EM volume'      
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              bcaughey@niaid.nih.gov 
_pdbx_contact_author.name_first         Byron 
_pdbx_contact_author.name_last          Caughey 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3928-6101 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Caughey, B.'  1 0000-0002-3928-6101 
'Hoyt, F.'     2 0000-0001-9020-6309 
'Alam, P.'     3 0000-0002-4484-8340 
'Artikis, E.'  4 0000-0001-8643-7403 
'Soukup, J.'   5 0000-0002-0459-9394 
'Hughson, A.'  6 0000-0002-1693-1315 
'Schwartz, C.' 7 0000-0002-0490-6040 
'Race, B.'     8 0000-0002-5334-1023 
'Barbian, K.'  9 0000-0001-9861-6150 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   DE 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acta Neuropathol' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1432-0533 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            148 
_citation.language                  ? 
_citation.page_first                56 
_citation.page_last                 56 
_citation.title                     'Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1007/s00401-024-02813-y 
_citation.pdbx_database_id_PubMed   39448454 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Alam, P.'       1  ? 
primary 'Hoyt, F.'       2  ? 
primary 'Artikis, E.'    3  ? 
primary 'Soukup, J.'     4  ? 
primary 'Hughson, A.G.'  5  ? 
primary 'Schwartz, C.L.' 6  ? 
primary 'Barbian, K.'    7  ? 
primary 'Miller, M.W.'   8  ? 
primary 'Race, B.'       9  ? 
primary 'Caughey, B.'    10 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 nat 
_entity.pdbx_description           'Major prion protein' 
_entity.formula_weight             27965.486 
_entity.pdbx_number_of_molecules   5 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPH
GGGWGQPHGGGGWGQGGTHSQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRY
PNQVYYRPVDQYNNQNTFVHDCVNITVKQHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGASVILFSS
PPVILLISFLIFLIVG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPH
GGGWGQPHGGGGWGQGGTHSQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRY
PNQVYYRPVDQYNNQNTFVHDCVNITVKQHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGASVILFSS
PPVILLISFLIFLIVG
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   VAL n 
1 3   LYS n 
1 4   SER n 
1 5   HIS n 
1 6   ILE n 
1 7   GLY n 
1 8   SER n 
1 9   TRP n 
1 10  ILE n 
1 11  LEU n 
1 12  VAL n 
1 13  LEU n 
1 14  PHE n 
1 15  VAL n 
1 16  ALA n 
1 17  MET n 
1 18  TRP n 
1 19  SER n 
1 20  ASP n 
1 21  VAL n 
1 22  GLY n 
1 23  LEU n 
1 24  CYS n 
1 25  LYS n 
1 26  LYS n 
1 27  ARG n 
1 28  PRO n 
1 29  LYS n 
1 30  PRO n 
1 31  GLY n 
1 32  GLY n 
1 33  GLY n 
1 34  TRP n 
1 35  ASN n 
1 36  THR n 
1 37  GLY n 
1 38  GLY n 
1 39  SER n 
1 40  ARG n 
1 41  TYR n 
1 42  PRO n 
1 43  GLY n 
1 44  GLN n 
1 45  GLY n 
1 46  SER n 
1 47  PRO n 
1 48  GLY n 
1 49  GLY n 
1 50  ASN n 
1 51  ARG n 
1 52  TYR n 
1 53  PRO n 
1 54  PRO n 
1 55  GLN n 
1 56  GLY n 
1 57  GLY n 
1 58  GLY n 
1 59  GLY n 
1 60  TRP n 
1 61  GLY n 
1 62  GLN n 
1 63  PRO n 
1 64  HIS n 
1 65  GLY n 
1 66  GLY n 
1 67  GLY n 
1 68  TRP n 
1 69  GLY n 
1 70  GLN n 
1 71  PRO n 
1 72  HIS n 
1 73  GLY n 
1 74  GLY n 
1 75  GLY n 
1 76  TRP n 
1 77  GLY n 
1 78  GLN n 
1 79  PRO n 
1 80  HIS n 
1 81  GLY n 
1 82  GLY n 
1 83  GLY n 
1 84  TRP n 
1 85  GLY n 
1 86  GLN n 
1 87  PRO n 
1 88  HIS n 
1 89  GLY n 
1 90  GLY n 
1 91  GLY n 
1 92  GLY n 
1 93  TRP n 
1 94  GLY n 
1 95  GLN n 
1 96  GLY n 
1 97  GLY n 
1 98  THR n 
1 99  HIS n 
1 100 SER n 
1 101 GLN n 
1 102 TRP n 
1 103 ASN n 
1 104 LYS n 
1 105 PRO n 
1 106 SER n 
1 107 LYS n 
1 108 PRO n 
1 109 LYS n 
1 110 THR n 
1 111 ASN n 
1 112 MET n 
1 113 LYS n 
1 114 HIS n 
1 115 VAL n 
1 116 ALA n 
1 117 GLY n 
1 118 ALA n 
1 119 ALA n 
1 120 ALA n 
1 121 ALA n 
1 122 GLY n 
1 123 ALA n 
1 124 VAL n 
1 125 VAL n 
1 126 GLY n 
1 127 GLY n 
1 128 LEU n 
1 129 GLY n 
1 130 GLY n 
1 131 TYR n 
1 132 MET n 
1 133 LEU n 
1 134 GLY n 
1 135 SER n 
1 136 ALA n 
1 137 MET n 
1 138 SER n 
1 139 ARG n 
1 140 PRO n 
1 141 LEU n 
1 142 ILE n 
1 143 HIS n 
1 144 PHE n 
1 145 GLY n 
1 146 ASN n 
1 147 ASP n 
1 148 TYR n 
1 149 GLU n 
1 150 ASP n 
1 151 ARG n 
1 152 TYR n 
1 153 TYR n 
1 154 ARG n 
1 155 GLU n 
1 156 ASN n 
1 157 MET n 
1 158 TYR n 
1 159 ARG n 
1 160 TYR n 
1 161 PRO n 
1 162 ASN n 
1 163 GLN n 
1 164 VAL n 
1 165 TYR n 
1 166 TYR n 
1 167 ARG n 
1 168 PRO n 
1 169 VAL n 
1 170 ASP n 
1 171 GLN n 
1 172 TYR n 
1 173 ASN n 
1 174 ASN n 
1 175 GLN n 
1 176 ASN n 
1 177 THR n 
1 178 PHE n 
1 179 VAL n 
1 180 HIS n 
1 181 ASP n 
1 182 CYS n 
1 183 VAL n 
1 184 ASN n 
1 185 ILE n 
1 186 THR n 
1 187 VAL n 
1 188 LYS n 
1 189 GLN n 
1 190 HIS n 
1 191 THR n 
1 192 VAL n 
1 193 THR n 
1 194 THR n 
1 195 THR n 
1 196 THR n 
1 197 LYS n 
1 198 GLY n 
1 199 GLU n 
1 200 ASN n 
1 201 PHE n 
1 202 THR n 
1 203 GLU n 
1 204 THR n 
1 205 ASP n 
1 206 ILE n 
1 207 LYS n 
1 208 MET n 
1 209 MET n 
1 210 GLU n 
1 211 ARG n 
1 212 VAL n 
1 213 VAL n 
1 214 GLU n 
1 215 GLN n 
1 216 MET n 
1 217 CYS n 
1 218 ILE n 
1 219 THR n 
1 220 GLN n 
1 221 TYR n 
1 222 GLN n 
1 223 ARG n 
1 224 GLU n 
1 225 SER n 
1 226 GLN n 
1 227 ALA n 
1 228 TYR n 
1 229 TYR n 
1 230 GLN n 
1 231 ARG n 
1 232 GLY n 
1 233 ALA n 
1 234 SER n 
1 235 VAL n 
1 236 ILE n 
1 237 LEU n 
1 238 PHE n 
1 239 SER n 
1 240 SER n 
1 241 PRO n 
1 242 PRO n 
1 243 VAL n 
1 244 ILE n 
1 245 LEU n 
1 246 LEU n 
1 247 ILE n 
1 248 SER n 
1 249 PHE n 
1 250 LEU n 
1 251 ILE n 
1 252 PHE n 
1 253 LEU n 
1 254 ILE n 
1 255 VAL n 
1 256 GLY n 
# 
_entity_src_nat.entity_id                  1 
_entity_src_nat.pdbx_src_id                1 
_entity_src_nat.pdbx_alt_source_flag       sample 
_entity_src_nat.pdbx_beg_seq_num           1 
_entity_src_nat.pdbx_end_seq_num           256 
_entity_src_nat.common_name                'white-tailed deer' 
_entity_src_nat.pdbx_organism_scientific   'Odocoileus virginianus' 
_entity_src_nat.pdbx_ncbi_taxonomy_id      9874 
_entity_src_nat.genus                      ? 
_entity_src_nat.species                    ? 
_entity_src_nat.strain                     ? 
_entity_src_nat.tissue                     ? 
_entity_src_nat.tissue_fraction            ? 
_entity_src_nat.pdbx_secretion             ? 
_entity_src_nat.pdbx_fragment              ? 
_entity_src_nat.pdbx_variant               ? 
_entity_src_nat.pdbx_cell_line             ? 
_entity_src_nat.pdbx_atcc                  ? 
_entity_src_nat.pdbx_cellular_location     ? 
_entity_src_nat.pdbx_organ                 ? 
_entity_src_nat.pdbx_organelle             ? 
_entity_src_nat.pdbx_cell                  ? 
_entity_src_nat.pdbx_plasmid_name          ? 
_entity_src_nat.pdbx_plasmid_details       ? 
_entity_src_nat.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   VAL 2   2   ?   ?   ?   A . n 
A 1 3   LYS 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   ?   ?   ?   A . n 
A 1 5   HIS 5   5   ?   ?   ?   A . n 
A 1 6   ILE 6   6   ?   ?   ?   A . n 
A 1 7   GLY 7   7   ?   ?   ?   A . n 
A 1 8   SER 8   8   ?   ?   ?   A . n 
A 1 9   TRP 9   9   ?   ?   ?   A . n 
A 1 10  ILE 10  10  ?   ?   ?   A . n 
A 1 11  LEU 11  11  ?   ?   ?   A . n 
A 1 12  VAL 12  12  ?   ?   ?   A . n 
A 1 13  LEU 13  13  ?   ?   ?   A . n 
A 1 14  PHE 14  14  ?   ?   ?   A . n 
A 1 15  VAL 15  15  ?   ?   ?   A . n 
A 1 16  ALA 16  16  ?   ?   ?   A . n 
A 1 17  MET 17  17  ?   ?   ?   A . n 
A 1 18  TRP 18  18  ?   ?   ?   A . n 
A 1 19  SER 19  19  ?   ?   ?   A . n 
A 1 20  ASP 20  20  ?   ?   ?   A . n 
A 1 21  VAL 21  21  ?   ?   ?   A . n 
A 1 22  GLY 22  22  ?   ?   ?   A . n 
A 1 23  LEU 23  23  ?   ?   ?   A . n 
A 1 24  CYS 24  24  ?   ?   ?   A . n 
A 1 25  LYS 25  25  ?   ?   ?   A . n 
A 1 26  LYS 26  26  ?   ?   ?   A . n 
A 1 27  ARG 27  27  ?   ?   ?   A . n 
A 1 28  PRO 28  28  ?   ?   ?   A . n 
A 1 29  LYS 29  29  ?   ?   ?   A . n 
A 1 30  PRO 30  30  ?   ?   ?   A . n 
A 1 31  GLY 31  31  ?   ?   ?   A . n 
A 1 32  GLY 32  32  ?   ?   ?   A . n 
A 1 33  GLY 33  33  ?   ?   ?   A . n 
A 1 34  TRP 34  34  ?   ?   ?   A . n 
A 1 35  ASN 35  35  ?   ?   ?   A . n 
A 1 36  THR 36  36  ?   ?   ?   A . n 
A 1 37  GLY 37  37  ?   ?   ?   A . n 
A 1 38  GLY 38  38  ?   ?   ?   A . n 
A 1 39  SER 39  39  ?   ?   ?   A . n 
A 1 40  ARG 40  40  ?   ?   ?   A . n 
A 1 41  TYR 41  41  ?   ?   ?   A . n 
A 1 42  PRO 42  42  ?   ?   ?   A . n 
A 1 43  GLY 43  43  ?   ?   ?   A . n 
A 1 44  GLN 44  44  ?   ?   ?   A . n 
A 1 45  GLY 45  45  ?   ?   ?   A . n 
A 1 46  SER 46  46  ?   ?   ?   A . n 
A 1 47  PRO 47  47  ?   ?   ?   A . n 
A 1 48  GLY 48  48  ?   ?   ?   A . n 
A 1 49  GLY 49  49  ?   ?   ?   A . n 
A 1 50  ASN 50  50  ?   ?   ?   A . n 
A 1 51  ARG 51  51  ?   ?   ?   A . n 
A 1 52  TYR 52  52  ?   ?   ?   A . n 
A 1 53  PRO 53  53  ?   ?   ?   A . n 
A 1 54  PRO 54  54  ?   ?   ?   A . n 
A 1 55  GLN 55  55  ?   ?   ?   A . n 
A 1 56  GLY 56  56  ?   ?   ?   A . n 
A 1 57  GLY 57  57  ?   ?   ?   A . n 
A 1 58  GLY 58  58  ?   ?   ?   A . n 
A 1 59  GLY 59  59  ?   ?   ?   A . n 
A 1 60  TRP 60  60  ?   ?   ?   A . n 
A 1 61  GLY 61  61  ?   ?   ?   A . n 
A 1 62  GLN 62  62  ?   ?   ?   A . n 
A 1 63  PRO 63  63  ?   ?   ?   A . n 
A 1 64  HIS 64  64  ?   ?   ?   A . n 
A 1 65  GLY 65  65  ?   ?   ?   A . n 
A 1 66  GLY 66  66  ?   ?   ?   A . n 
A 1 67  GLY 67  67  ?   ?   ?   A . n 
A 1 68  TRP 68  68  ?   ?   ?   A . n 
A 1 69  GLY 69  69  ?   ?   ?   A . n 
A 1 70  GLN 70  70  ?   ?   ?   A . n 
A 1 71  PRO 71  71  ?   ?   ?   A . n 
A 1 72  HIS 72  72  ?   ?   ?   A . n 
A 1 73  GLY 73  73  ?   ?   ?   A . n 
A 1 74  GLY 74  74  ?   ?   ?   A . n 
A 1 75  GLY 75  75  ?   ?   ?   A . n 
A 1 76  TRP 76  76  ?   ?   ?   A . n 
A 1 77  GLY 77  77  ?   ?   ?   A . n 
A 1 78  GLN 78  78  ?   ?   ?   A . n 
A 1 79  PRO 79  79  ?   ?   ?   A . n 
A 1 80  HIS 80  80  ?   ?   ?   A . n 
A 1 81  GLY 81  81  ?   ?   ?   A . n 
A 1 82  GLY 82  82  ?   ?   ?   A . n 
A 1 83  GLY 83  83  ?   ?   ?   A . n 
A 1 84  TRP 84  84  ?   ?   ?   A . n 
A 1 85  GLY 85  85  ?   ?   ?   A . n 
A 1 86  GLN 86  86  ?   ?   ?   A . n 
A 1 87  PRO 87  87  ?   ?   ?   A . n 
A 1 88  HIS 88  88  ?   ?   ?   A . n 
A 1 89  GLY 89  89  ?   ?   ?   A . n 
A 1 90  GLY 90  90  ?   ?   ?   A . n 
A 1 91  GLY 91  91  ?   ?   ?   A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  TRP 93  93  93  TRP TRP A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  GLN 95  95  95  GLN GLN A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  GLY 97  97  97  GLY GLY A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  HIS 99  99  99  HIS HIS A . n 
A 1 100 SER 100 100 100 SER SER A . n 
A 1 101 GLN 101 101 101 GLN GLN A . n 
A 1 102 TRP 102 102 102 TRP TRP A . n 
A 1 103 ASN 103 103 103 ASN ASN A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 PRO 105 105 105 PRO PRO A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 LYS 107 107 107 LYS LYS A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 LYS 109 109 109 LYS LYS A . n 
A 1 110 THR 110 110 110 THR THR A . n 
A 1 111 ASN 111 111 111 ASN ASN A . n 
A 1 112 MET 112 112 112 MET MET A . n 
A 1 113 LYS 113 113 113 LYS LYS A . n 
A 1 114 HIS 114 114 114 HIS HIS A . n 
A 1 115 VAL 115 115 115 VAL VAL A . n 
A 1 116 ALA 116 116 116 ALA ALA A . n 
A 1 117 GLY 117 117 117 GLY GLY A . n 
A 1 118 ALA 118 118 118 ALA ALA A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 ALA 120 120 120 ALA ALA A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 ALA 123 123 123 ALA ALA A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 GLY 126 126 126 GLY GLY A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 LEU 128 128 128 LEU LEU A . n 
A 1 129 GLY 129 129 129 GLY GLY A . n 
A 1 130 GLY 130 130 130 GLY GLY A . n 
A 1 131 TYR 131 131 131 TYR TYR A . n 
A 1 132 MET 132 132 132 MET MET A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 SER 135 135 135 SER SER A . n 
A 1 136 ALA 136 136 136 ALA ALA A . n 
A 1 137 MET 137 137 137 MET MET A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 PRO 140 140 140 PRO PRO A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 ILE 142 142 142 ILE ILE A . n 
A 1 143 HIS 143 143 143 HIS HIS A . n 
A 1 144 PHE 144 144 144 PHE PHE A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 ASN 146 146 146 ASN ASN A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 TYR 148 148 148 TYR TYR A . n 
A 1 149 GLU 149 149 149 GLU GLU A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 ARG 151 151 151 ARG ARG A . n 
A 1 152 TYR 152 152 152 TYR TYR A . n 
A 1 153 TYR 153 153 153 TYR TYR A . n 
A 1 154 ARG 154 154 154 ARG ARG A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 ASN 156 156 156 ASN ASN A . n 
A 1 157 MET 157 157 157 MET MET A . n 
A 1 158 TYR 158 158 158 TYR TYR A . n 
A 1 159 ARG 159 159 159 ARG ARG A . n 
A 1 160 TYR 160 160 160 TYR TYR A . n 
A 1 161 PRO 161 161 161 PRO PRO A . n 
A 1 162 ASN 162 162 162 ASN ASN A . n 
A 1 163 GLN 163 163 163 GLN GLN A . n 
A 1 164 VAL 164 164 164 VAL VAL A . n 
A 1 165 TYR 165 165 165 TYR TYR A . n 
A 1 166 TYR 166 166 166 TYR TYR A . n 
A 1 167 ARG 167 167 167 ARG ARG A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 VAL 169 169 169 VAL VAL A . n 
A 1 170 ASP 170 170 170 ASP ASP A . n 
A 1 171 GLN 171 171 171 GLN GLN A . n 
A 1 172 TYR 172 172 172 TYR TYR A . n 
A 1 173 ASN 173 173 173 ASN ASN A . n 
A 1 174 ASN 174 174 174 ASN ASN A . n 
A 1 175 GLN 175 175 175 GLN GLN A . n 
A 1 176 ASN 176 176 176 ASN ASN A . n 
A 1 177 THR 177 177 177 THR THR A . n 
A 1 178 PHE 178 178 178 PHE PHE A . n 
A 1 179 VAL 179 179 179 VAL VAL A . n 
A 1 180 HIS 180 180 180 HIS HIS A . n 
A 1 181 ASP 181 181 181 ASP ASP A . n 
A 1 182 CYS 182 182 182 CYS CYS A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 ASN 184 184 184 ASN ASN A . n 
A 1 185 ILE 185 185 185 ILE ILE A . n 
A 1 186 THR 186 186 186 THR THR A . n 
A 1 187 VAL 187 187 187 VAL VAL A . n 
A 1 188 LYS 188 188 188 LYS LYS A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 HIS 190 190 190 HIS HIS A . n 
A 1 191 THR 191 191 191 THR THR A . n 
A 1 192 VAL 192 192 192 VAL VAL A . n 
A 1 193 THR 193 193 193 THR THR A . n 
A 1 194 THR 194 194 194 THR THR A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 LYS 197 197 197 LYS LYS A . n 
A 1 198 GLY 198 198 198 GLY GLY A . n 
A 1 199 GLU 199 199 199 GLU GLU A . n 
A 1 200 ASN 200 200 200 ASN ASN A . n 
A 1 201 PHE 201 201 201 PHE PHE A . n 
A 1 202 THR 202 202 202 THR THR A . n 
A 1 203 GLU 203 203 203 GLU GLU A . n 
A 1 204 THR 204 204 204 THR THR A . n 
A 1 205 ASP 205 205 205 ASP ASP A . n 
A 1 206 ILE 206 206 206 ILE ILE A . n 
A 1 207 LYS 207 207 207 LYS LYS A . n 
A 1 208 MET 208 208 208 MET MET A . n 
A 1 209 MET 209 209 209 MET MET A . n 
A 1 210 GLU 210 210 210 GLU GLU A . n 
A 1 211 ARG 211 211 211 ARG ARG A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 GLU 214 214 214 GLU GLU A . n 
A 1 215 GLN 215 215 215 GLN GLN A . n 
A 1 216 MET 216 216 216 MET MET A . n 
A 1 217 CYS 217 217 217 CYS CYS A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 GLN 220 220 220 GLN GLN A . n 
A 1 221 TYR 221 221 221 TYR TYR A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 ARG 223 223 223 ARG ARG A . n 
A 1 224 GLU 224 224 224 GLU GLU A . n 
A 1 225 SER 225 225 225 SER SER A . n 
A 1 226 GLN 226 226 226 GLN GLN A . n 
A 1 227 ALA 227 227 227 ALA ALA A . n 
A 1 228 TYR 228 228 228 TYR TYR A . n 
A 1 229 TYR 229 229 229 TYR TYR A . n 
A 1 230 GLN 230 230 ?   ?   ?   A . n 
A 1 231 ARG 231 231 ?   ?   ?   A . n 
A 1 232 GLY 232 232 ?   ?   ?   A . n 
A 1 233 ALA 233 233 ?   ?   ?   A . n 
A 1 234 SER 234 234 ?   ?   ?   A . n 
A 1 235 VAL 235 235 ?   ?   ?   A . n 
A 1 236 ILE 236 236 ?   ?   ?   A . n 
A 1 237 LEU 237 237 ?   ?   ?   A . n 
A 1 238 PHE 238 238 ?   ?   ?   A . n 
A 1 239 SER 239 239 ?   ?   ?   A . n 
A 1 240 SER 240 240 ?   ?   ?   A . n 
A 1 241 PRO 241 241 ?   ?   ?   A . n 
A 1 242 PRO 242 242 ?   ?   ?   A . n 
A 1 243 VAL 243 243 ?   ?   ?   A . n 
A 1 244 ILE 244 244 ?   ?   ?   A . n 
A 1 245 LEU 245 245 ?   ?   ?   A . n 
A 1 246 LEU 246 246 ?   ?   ?   A . n 
A 1 247 ILE 247 247 ?   ?   ?   A . n 
A 1 248 SER 248 248 ?   ?   ?   A . n 
A 1 249 PHE 249 249 ?   ?   ?   A . n 
A 1 250 LEU 250 250 ?   ?   ?   A . n 
A 1 251 ILE 251 251 ?   ?   ?   A . n 
A 1 252 PHE 252 252 ?   ?   ?   A . n 
A 1 253 LEU 253 253 ?   ?   ?   A . n 
A 1 254 ILE 254 254 ?   ?   ?   A . n 
A 1 255 VAL 255 255 ?   ?   ?   A . n 
A 1 256 GLY 256 256 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   VAL 2   2   ?   ?   ?   B . n 
B 1 3   LYS 3   3   ?   ?   ?   B . n 
B 1 4   SER 4   4   ?   ?   ?   B . n 
B 1 5   HIS 5   5   ?   ?   ?   B . n 
B 1 6   ILE 6   6   ?   ?   ?   B . n 
B 1 7   GLY 7   7   ?   ?   ?   B . n 
B 1 8   SER 8   8   ?   ?   ?   B . n 
B 1 9   TRP 9   9   ?   ?   ?   B . n 
B 1 10  ILE 10  10  ?   ?   ?   B . n 
B 1 11  LEU 11  11  ?   ?   ?   B . n 
B 1 12  VAL 12  12  ?   ?   ?   B . n 
B 1 13  LEU 13  13  ?   ?   ?   B . n 
B 1 14  PHE 14  14  ?   ?   ?   B . n 
B 1 15  VAL 15  15  ?   ?   ?   B . n 
B 1 16  ALA 16  16  ?   ?   ?   B . n 
B 1 17  MET 17  17  ?   ?   ?   B . n 
B 1 18  TRP 18  18  ?   ?   ?   B . n 
B 1 19  SER 19  19  ?   ?   ?   B . n 
B 1 20  ASP 20  20  ?   ?   ?   B . n 
B 1 21  VAL 21  21  ?   ?   ?   B . n 
B 1 22  GLY 22  22  ?   ?   ?   B . n 
B 1 23  LEU 23  23  ?   ?   ?   B . n 
B 1 24  CYS 24  24  ?   ?   ?   B . n 
B 1 25  LYS 25  25  ?   ?   ?   B . n 
B 1 26  LYS 26  26  ?   ?   ?   B . n 
B 1 27  ARG 27  27  ?   ?   ?   B . n 
B 1 28  PRO 28  28  ?   ?   ?   B . n 
B 1 29  LYS 29  29  ?   ?   ?   B . n 
B 1 30  PRO 30  30  ?   ?   ?   B . n 
B 1 31  GLY 31  31  ?   ?   ?   B . n 
B 1 32  GLY 32  32  ?   ?   ?   B . n 
B 1 33  GLY 33  33  ?   ?   ?   B . n 
B 1 34  TRP 34  34  ?   ?   ?   B . n 
B 1 35  ASN 35  35  ?   ?   ?   B . n 
B 1 36  THR 36  36  ?   ?   ?   B . n 
B 1 37  GLY 37  37  ?   ?   ?   B . n 
B 1 38  GLY 38  38  ?   ?   ?   B . n 
B 1 39  SER 39  39  ?   ?   ?   B . n 
B 1 40  ARG 40  40  ?   ?   ?   B . n 
B 1 41  TYR 41  41  ?   ?   ?   B . n 
B 1 42  PRO 42  42  ?   ?   ?   B . n 
B 1 43  GLY 43  43  ?   ?   ?   B . n 
B 1 44  GLN 44  44  ?   ?   ?   B . n 
B 1 45  GLY 45  45  ?   ?   ?   B . n 
B 1 46  SER 46  46  ?   ?   ?   B . n 
B 1 47  PRO 47  47  ?   ?   ?   B . n 
B 1 48  GLY 48  48  ?   ?   ?   B . n 
B 1 49  GLY 49  49  ?   ?   ?   B . n 
B 1 50  ASN 50  50  ?   ?   ?   B . n 
B 1 51  ARG 51  51  ?   ?   ?   B . n 
B 1 52  TYR 52  52  ?   ?   ?   B . n 
B 1 53  PRO 53  53  ?   ?   ?   B . n 
B 1 54  PRO 54  54  ?   ?   ?   B . n 
B 1 55  GLN 55  55  ?   ?   ?   B . n 
B 1 56  GLY 56  56  ?   ?   ?   B . n 
B 1 57  GLY 57  57  ?   ?   ?   B . n 
B 1 58  GLY 58  58  ?   ?   ?   B . n 
B 1 59  GLY 59  59  ?   ?   ?   B . n 
B 1 60  TRP 60  60  ?   ?   ?   B . n 
B 1 61  GLY 61  61  ?   ?   ?   B . n 
B 1 62  GLN 62  62  ?   ?   ?   B . n 
B 1 63  PRO 63  63  ?   ?   ?   B . n 
B 1 64  HIS 64  64  ?   ?   ?   B . n 
B 1 65  GLY 65  65  ?   ?   ?   B . n 
B 1 66  GLY 66  66  ?   ?   ?   B . n 
B 1 67  GLY 67  67  ?   ?   ?   B . n 
B 1 68  TRP 68  68  ?   ?   ?   B . n 
B 1 69  GLY 69  69  ?   ?   ?   B . n 
B 1 70  GLN 70  70  ?   ?   ?   B . n 
B 1 71  PRO 71  71  ?   ?   ?   B . n 
B 1 72  HIS 72  72  ?   ?   ?   B . n 
B 1 73  GLY 73  73  ?   ?   ?   B . n 
B 1 74  GLY 74  74  ?   ?   ?   B . n 
B 1 75  GLY 75  75  ?   ?   ?   B . n 
B 1 76  TRP 76  76  ?   ?   ?   B . n 
B 1 77  GLY 77  77  ?   ?   ?   B . n 
B 1 78  GLN 78  78  ?   ?   ?   B . n 
B 1 79  PRO 79  79  ?   ?   ?   B . n 
B 1 80  HIS 80  80  ?   ?   ?   B . n 
B 1 81  GLY 81  81  ?   ?   ?   B . n 
B 1 82  GLY 82  82  ?   ?   ?   B . n 
B 1 83  GLY 83  83  ?   ?   ?   B . n 
B 1 84  TRP 84  84  ?   ?   ?   B . n 
B 1 85  GLY 85  85  ?   ?   ?   B . n 
B 1 86  GLN 86  86  ?   ?   ?   B . n 
B 1 87  PRO 87  87  ?   ?   ?   B . n 
B 1 88  HIS 88  88  ?   ?   ?   B . n 
B 1 89  GLY 89  89  ?   ?   ?   B . n 
B 1 90  GLY 90  90  ?   ?   ?   B . n 
B 1 91  GLY 91  91  ?   ?   ?   B . n 
B 1 92  GLY 92  92  92  GLY GLY B . n 
B 1 93  TRP 93  93  93  TRP TRP B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  GLN 95  95  95  GLN GLN B . n 
B 1 96  GLY 96  96  96  GLY GLY B . n 
B 1 97  GLY 97  97  97  GLY GLY B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  HIS 99  99  99  HIS HIS B . n 
B 1 100 SER 100 100 100 SER SER B . n 
B 1 101 GLN 101 101 101 GLN GLN B . n 
B 1 102 TRP 102 102 102 TRP TRP B . n 
B 1 103 ASN 103 103 103 ASN ASN B . n 
B 1 104 LYS 104 104 104 LYS LYS B . n 
B 1 105 PRO 105 105 105 PRO PRO B . n 
B 1 106 SER 106 106 106 SER SER B . n 
B 1 107 LYS 107 107 107 LYS LYS B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 LYS 109 109 109 LYS LYS B . n 
B 1 110 THR 110 110 110 THR THR B . n 
B 1 111 ASN 111 111 111 ASN ASN B . n 
B 1 112 MET 112 112 112 MET MET B . n 
B 1 113 LYS 113 113 113 LYS LYS B . n 
B 1 114 HIS 114 114 114 HIS HIS B . n 
B 1 115 VAL 115 115 115 VAL VAL B . n 
B 1 116 ALA 116 116 116 ALA ALA B . n 
B 1 117 GLY 117 117 117 GLY GLY B . n 
B 1 118 ALA 118 118 118 ALA ALA B . n 
B 1 119 ALA 119 119 119 ALA ALA B . n 
B 1 120 ALA 120 120 120 ALA ALA B . n 
B 1 121 ALA 121 121 121 ALA ALA B . n 
B 1 122 GLY 122 122 122 GLY GLY B . n 
B 1 123 ALA 123 123 123 ALA ALA B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 GLY 126 126 126 GLY GLY B . n 
B 1 127 GLY 127 127 127 GLY GLY B . n 
B 1 128 LEU 128 128 128 LEU LEU B . n 
B 1 129 GLY 129 129 129 GLY GLY B . n 
B 1 130 GLY 130 130 130 GLY GLY B . n 
B 1 131 TYR 131 131 131 TYR TYR B . n 
B 1 132 MET 132 132 132 MET MET B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 GLY 134 134 134 GLY GLY B . n 
B 1 135 SER 135 135 135 SER SER B . n 
B 1 136 ALA 136 136 136 ALA ALA B . n 
B 1 137 MET 137 137 137 MET MET B . n 
B 1 138 SER 138 138 138 SER SER B . n 
B 1 139 ARG 139 139 139 ARG ARG B . n 
B 1 140 PRO 140 140 140 PRO PRO B . n 
B 1 141 LEU 141 141 141 LEU LEU B . n 
B 1 142 ILE 142 142 142 ILE ILE B . n 
B 1 143 HIS 143 143 143 HIS HIS B . n 
B 1 144 PHE 144 144 144 PHE PHE B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 ASN 146 146 146 ASN ASN B . n 
B 1 147 ASP 147 147 147 ASP ASP B . n 
B 1 148 TYR 148 148 148 TYR TYR B . n 
B 1 149 GLU 149 149 149 GLU GLU B . n 
B 1 150 ASP 150 150 150 ASP ASP B . n 
B 1 151 ARG 151 151 151 ARG ARG B . n 
B 1 152 TYR 152 152 152 TYR TYR B . n 
B 1 153 TYR 153 153 153 TYR TYR B . n 
B 1 154 ARG 154 154 154 ARG ARG B . n 
B 1 155 GLU 155 155 155 GLU GLU B . n 
B 1 156 ASN 156 156 156 ASN ASN B . n 
B 1 157 MET 157 157 157 MET MET B . n 
B 1 158 TYR 158 158 158 TYR TYR B . n 
B 1 159 ARG 159 159 159 ARG ARG B . n 
B 1 160 TYR 160 160 160 TYR TYR B . n 
B 1 161 PRO 161 161 161 PRO PRO B . n 
B 1 162 ASN 162 162 162 ASN ASN B . n 
B 1 163 GLN 163 163 163 GLN GLN B . n 
B 1 164 VAL 164 164 164 VAL VAL B . n 
B 1 165 TYR 165 165 165 TYR TYR B . n 
B 1 166 TYR 166 166 166 TYR TYR B . n 
B 1 167 ARG 167 167 167 ARG ARG B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 VAL 169 169 169 VAL VAL B . n 
B 1 170 ASP 170 170 170 ASP ASP B . n 
B 1 171 GLN 171 171 171 GLN GLN B . n 
B 1 172 TYR 172 172 172 TYR TYR B . n 
B 1 173 ASN 173 173 173 ASN ASN B . n 
B 1 174 ASN 174 174 174 ASN ASN B . n 
B 1 175 GLN 175 175 175 GLN GLN B . n 
B 1 176 ASN 176 176 176 ASN ASN B . n 
B 1 177 THR 177 177 177 THR THR B . n 
B 1 178 PHE 178 178 178 PHE PHE B . n 
B 1 179 VAL 179 179 179 VAL VAL B . n 
B 1 180 HIS 180 180 180 HIS HIS B . n 
B 1 181 ASP 181 181 181 ASP ASP B . n 
B 1 182 CYS 182 182 182 CYS CYS B . n 
B 1 183 VAL 183 183 183 VAL VAL B . n 
B 1 184 ASN 184 184 184 ASN ASN B . n 
B 1 185 ILE 185 185 185 ILE ILE B . n 
B 1 186 THR 186 186 186 THR THR B . n 
B 1 187 VAL 187 187 187 VAL VAL B . n 
B 1 188 LYS 188 188 188 LYS LYS B . n 
B 1 189 GLN 189 189 189 GLN GLN B . n 
B 1 190 HIS 190 190 190 HIS HIS B . n 
B 1 191 THR 191 191 191 THR THR B . n 
B 1 192 VAL 192 192 192 VAL VAL B . n 
B 1 193 THR 193 193 193 THR THR B . n 
B 1 194 THR 194 194 194 THR THR B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 THR 196 196 196 THR THR B . n 
B 1 197 LYS 197 197 197 LYS LYS B . n 
B 1 198 GLY 198 198 198 GLY GLY B . n 
B 1 199 GLU 199 199 199 GLU GLU B . n 
B 1 200 ASN 200 200 200 ASN ASN B . n 
B 1 201 PHE 201 201 201 PHE PHE B . n 
B 1 202 THR 202 202 202 THR THR B . n 
B 1 203 GLU 203 203 203 GLU GLU B . n 
B 1 204 THR 204 204 204 THR THR B . n 
B 1 205 ASP 205 205 205 ASP ASP B . n 
B 1 206 ILE 206 206 206 ILE ILE B . n 
B 1 207 LYS 207 207 207 LYS LYS B . n 
B 1 208 MET 208 208 208 MET MET B . n 
B 1 209 MET 209 209 209 MET MET B . n 
B 1 210 GLU 210 210 210 GLU GLU B . n 
B 1 211 ARG 211 211 211 ARG ARG B . n 
B 1 212 VAL 212 212 212 VAL VAL B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 GLU 214 214 214 GLU GLU B . n 
B 1 215 GLN 215 215 215 GLN GLN B . n 
B 1 216 MET 216 216 216 MET MET B . n 
B 1 217 CYS 217 217 217 CYS CYS B . n 
B 1 218 ILE 218 218 218 ILE ILE B . n 
B 1 219 THR 219 219 219 THR THR B . n 
B 1 220 GLN 220 220 220 GLN GLN B . n 
B 1 221 TYR 221 221 221 TYR TYR B . n 
B 1 222 GLN 222 222 222 GLN GLN B . n 
B 1 223 ARG 223 223 223 ARG ARG B . n 
B 1 224 GLU 224 224 224 GLU GLU B . n 
B 1 225 SER 225 225 225 SER SER B . n 
B 1 226 GLN 226 226 226 GLN GLN B . n 
B 1 227 ALA 227 227 227 ALA ALA B . n 
B 1 228 TYR 228 228 228 TYR TYR B . n 
B 1 229 TYR 229 229 229 TYR TYR B . n 
B 1 230 GLN 230 230 ?   ?   ?   B . n 
B 1 231 ARG 231 231 ?   ?   ?   B . n 
B 1 232 GLY 232 232 ?   ?   ?   B . n 
B 1 233 ALA 233 233 ?   ?   ?   B . n 
B 1 234 SER 234 234 ?   ?   ?   B . n 
B 1 235 VAL 235 235 ?   ?   ?   B . n 
B 1 236 ILE 236 236 ?   ?   ?   B . n 
B 1 237 LEU 237 237 ?   ?   ?   B . n 
B 1 238 PHE 238 238 ?   ?   ?   B . n 
B 1 239 SER 239 239 ?   ?   ?   B . n 
B 1 240 SER 240 240 ?   ?   ?   B . n 
B 1 241 PRO 241 241 ?   ?   ?   B . n 
B 1 242 PRO 242 242 ?   ?   ?   B . n 
B 1 243 VAL 243 243 ?   ?   ?   B . n 
B 1 244 ILE 244 244 ?   ?   ?   B . n 
B 1 245 LEU 245 245 ?   ?   ?   B . n 
B 1 246 LEU 246 246 ?   ?   ?   B . n 
B 1 247 ILE 247 247 ?   ?   ?   B . n 
B 1 248 SER 248 248 ?   ?   ?   B . n 
B 1 249 PHE 249 249 ?   ?   ?   B . n 
B 1 250 LEU 250 250 ?   ?   ?   B . n 
B 1 251 ILE 251 251 ?   ?   ?   B . n 
B 1 252 PHE 252 252 ?   ?   ?   B . n 
B 1 253 LEU 253 253 ?   ?   ?   B . n 
B 1 254 ILE 254 254 ?   ?   ?   B . n 
B 1 255 VAL 255 255 ?   ?   ?   B . n 
B 1 256 GLY 256 256 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   VAL 2   2   ?   ?   ?   C . n 
C 1 3   LYS 3   3   ?   ?   ?   C . n 
C 1 4   SER 4   4   ?   ?   ?   C . n 
C 1 5   HIS 5   5   ?   ?   ?   C . n 
C 1 6   ILE 6   6   ?   ?   ?   C . n 
C 1 7   GLY 7   7   ?   ?   ?   C . n 
C 1 8   SER 8   8   ?   ?   ?   C . n 
C 1 9   TRP 9   9   ?   ?   ?   C . n 
C 1 10  ILE 10  10  ?   ?   ?   C . n 
C 1 11  LEU 11  11  ?   ?   ?   C . n 
C 1 12  VAL 12  12  ?   ?   ?   C . n 
C 1 13  LEU 13  13  ?   ?   ?   C . n 
C 1 14  PHE 14  14  ?   ?   ?   C . n 
C 1 15  VAL 15  15  ?   ?   ?   C . n 
C 1 16  ALA 16  16  ?   ?   ?   C . n 
C 1 17  MET 17  17  ?   ?   ?   C . n 
C 1 18  TRP 18  18  ?   ?   ?   C . n 
C 1 19  SER 19  19  ?   ?   ?   C . n 
C 1 20  ASP 20  20  ?   ?   ?   C . n 
C 1 21  VAL 21  21  ?   ?   ?   C . n 
C 1 22  GLY 22  22  ?   ?   ?   C . n 
C 1 23  LEU 23  23  ?   ?   ?   C . n 
C 1 24  CYS 24  24  ?   ?   ?   C . n 
C 1 25  LYS 25  25  ?   ?   ?   C . n 
C 1 26  LYS 26  26  ?   ?   ?   C . n 
C 1 27  ARG 27  27  ?   ?   ?   C . n 
C 1 28  PRO 28  28  ?   ?   ?   C . n 
C 1 29  LYS 29  29  ?   ?   ?   C . n 
C 1 30  PRO 30  30  ?   ?   ?   C . n 
C 1 31  GLY 31  31  ?   ?   ?   C . n 
C 1 32  GLY 32  32  ?   ?   ?   C . n 
C 1 33  GLY 33  33  ?   ?   ?   C . n 
C 1 34  TRP 34  34  ?   ?   ?   C . n 
C 1 35  ASN 35  35  ?   ?   ?   C . n 
C 1 36  THR 36  36  ?   ?   ?   C . n 
C 1 37  GLY 37  37  ?   ?   ?   C . n 
C 1 38  GLY 38  38  ?   ?   ?   C . n 
C 1 39  SER 39  39  ?   ?   ?   C . n 
C 1 40  ARG 40  40  ?   ?   ?   C . n 
C 1 41  TYR 41  41  ?   ?   ?   C . n 
C 1 42  PRO 42  42  ?   ?   ?   C . n 
C 1 43  GLY 43  43  ?   ?   ?   C . n 
C 1 44  GLN 44  44  ?   ?   ?   C . n 
C 1 45  GLY 45  45  ?   ?   ?   C . n 
C 1 46  SER 46  46  ?   ?   ?   C . n 
C 1 47  PRO 47  47  ?   ?   ?   C . n 
C 1 48  GLY 48  48  ?   ?   ?   C . n 
C 1 49  GLY 49  49  ?   ?   ?   C . n 
C 1 50  ASN 50  50  ?   ?   ?   C . n 
C 1 51  ARG 51  51  ?   ?   ?   C . n 
C 1 52  TYR 52  52  ?   ?   ?   C . n 
C 1 53  PRO 53  53  ?   ?   ?   C . n 
C 1 54  PRO 54  54  ?   ?   ?   C . n 
C 1 55  GLN 55  55  ?   ?   ?   C . n 
C 1 56  GLY 56  56  ?   ?   ?   C . n 
C 1 57  GLY 57  57  ?   ?   ?   C . n 
C 1 58  GLY 58  58  ?   ?   ?   C . n 
C 1 59  GLY 59  59  ?   ?   ?   C . n 
C 1 60  TRP 60  60  ?   ?   ?   C . n 
C 1 61  GLY 61  61  ?   ?   ?   C . n 
C 1 62  GLN 62  62  ?   ?   ?   C . n 
C 1 63  PRO 63  63  ?   ?   ?   C . n 
C 1 64  HIS 64  64  ?   ?   ?   C . n 
C 1 65  GLY 65  65  ?   ?   ?   C . n 
C 1 66  GLY 66  66  ?   ?   ?   C . n 
C 1 67  GLY 67  67  ?   ?   ?   C . n 
C 1 68  TRP 68  68  ?   ?   ?   C . n 
C 1 69  GLY 69  69  ?   ?   ?   C . n 
C 1 70  GLN 70  70  ?   ?   ?   C . n 
C 1 71  PRO 71  71  ?   ?   ?   C . n 
C 1 72  HIS 72  72  ?   ?   ?   C . n 
C 1 73  GLY 73  73  ?   ?   ?   C . n 
C 1 74  GLY 74  74  ?   ?   ?   C . n 
C 1 75  GLY 75  75  ?   ?   ?   C . n 
C 1 76  TRP 76  76  ?   ?   ?   C . n 
C 1 77  GLY 77  77  ?   ?   ?   C . n 
C 1 78  GLN 78  78  ?   ?   ?   C . n 
C 1 79  PRO 79  79  ?   ?   ?   C . n 
C 1 80  HIS 80  80  ?   ?   ?   C . n 
C 1 81  GLY 81  81  ?   ?   ?   C . n 
C 1 82  GLY 82  82  ?   ?   ?   C . n 
C 1 83  GLY 83  83  ?   ?   ?   C . n 
C 1 84  TRP 84  84  ?   ?   ?   C . n 
C 1 85  GLY 85  85  ?   ?   ?   C . n 
C 1 86  GLN 86  86  ?   ?   ?   C . n 
C 1 87  PRO 87  87  ?   ?   ?   C . n 
C 1 88  HIS 88  88  ?   ?   ?   C . n 
C 1 89  GLY 89  89  ?   ?   ?   C . n 
C 1 90  GLY 90  90  ?   ?   ?   C . n 
C 1 91  GLY 91  91  ?   ?   ?   C . n 
C 1 92  GLY 92  92  92  GLY GLY C . n 
C 1 93  TRP 93  93  93  TRP TRP C . n 
C 1 94  GLY 94  94  94  GLY GLY C . n 
C 1 95  GLN 95  95  95  GLN GLN C . n 
C 1 96  GLY 96  96  96  GLY GLY C . n 
C 1 97  GLY 97  97  97  GLY GLY C . n 
C 1 98  THR 98  98  98  THR THR C . n 
C 1 99  HIS 99  99  99  HIS HIS C . n 
C 1 100 SER 100 100 100 SER SER C . n 
C 1 101 GLN 101 101 101 GLN GLN C . n 
C 1 102 TRP 102 102 102 TRP TRP C . n 
C 1 103 ASN 103 103 103 ASN ASN C . n 
C 1 104 LYS 104 104 104 LYS LYS C . n 
C 1 105 PRO 105 105 105 PRO PRO C . n 
C 1 106 SER 106 106 106 SER SER C . n 
C 1 107 LYS 107 107 107 LYS LYS C . n 
C 1 108 PRO 108 108 108 PRO PRO C . n 
C 1 109 LYS 109 109 109 LYS LYS C . n 
C 1 110 THR 110 110 110 THR THR C . n 
C 1 111 ASN 111 111 111 ASN ASN C . n 
C 1 112 MET 112 112 112 MET MET C . n 
C 1 113 LYS 113 113 113 LYS LYS C . n 
C 1 114 HIS 114 114 114 HIS HIS C . n 
C 1 115 VAL 115 115 115 VAL VAL C . n 
C 1 116 ALA 116 116 116 ALA ALA C . n 
C 1 117 GLY 117 117 117 GLY GLY C . n 
C 1 118 ALA 118 118 118 ALA ALA C . n 
C 1 119 ALA 119 119 119 ALA ALA C . n 
C 1 120 ALA 120 120 120 ALA ALA C . n 
C 1 121 ALA 121 121 121 ALA ALA C . n 
C 1 122 GLY 122 122 122 GLY GLY C . n 
C 1 123 ALA 123 123 123 ALA ALA C . n 
C 1 124 VAL 124 124 124 VAL VAL C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 GLY 126 126 126 GLY GLY C . n 
C 1 127 GLY 127 127 127 GLY GLY C . n 
C 1 128 LEU 128 128 128 LEU LEU C . n 
C 1 129 GLY 129 129 129 GLY GLY C . n 
C 1 130 GLY 130 130 130 GLY GLY C . n 
C 1 131 TYR 131 131 131 TYR TYR C . n 
C 1 132 MET 132 132 132 MET MET C . n 
C 1 133 LEU 133 133 133 LEU LEU C . n 
C 1 134 GLY 134 134 134 GLY GLY C . n 
C 1 135 SER 135 135 135 SER SER C . n 
C 1 136 ALA 136 136 136 ALA ALA C . n 
C 1 137 MET 137 137 137 MET MET C . n 
C 1 138 SER 138 138 138 SER SER C . n 
C 1 139 ARG 139 139 139 ARG ARG C . n 
C 1 140 PRO 140 140 140 PRO PRO C . n 
C 1 141 LEU 141 141 141 LEU LEU C . n 
C 1 142 ILE 142 142 142 ILE ILE C . n 
C 1 143 HIS 143 143 143 HIS HIS C . n 
C 1 144 PHE 144 144 144 PHE PHE C . n 
C 1 145 GLY 145 145 145 GLY GLY C . n 
C 1 146 ASN 146 146 146 ASN ASN C . n 
C 1 147 ASP 147 147 147 ASP ASP C . n 
C 1 148 TYR 148 148 148 TYR TYR C . n 
C 1 149 GLU 149 149 149 GLU GLU C . n 
C 1 150 ASP 150 150 150 ASP ASP C . n 
C 1 151 ARG 151 151 151 ARG ARG C . n 
C 1 152 TYR 152 152 152 TYR TYR C . n 
C 1 153 TYR 153 153 153 TYR TYR C . n 
C 1 154 ARG 154 154 154 ARG ARG C . n 
C 1 155 GLU 155 155 155 GLU GLU C . n 
C 1 156 ASN 156 156 156 ASN ASN C . n 
C 1 157 MET 157 157 157 MET MET C . n 
C 1 158 TYR 158 158 158 TYR TYR C . n 
C 1 159 ARG 159 159 159 ARG ARG C . n 
C 1 160 TYR 160 160 160 TYR TYR C . n 
C 1 161 PRO 161 161 161 PRO PRO C . n 
C 1 162 ASN 162 162 162 ASN ASN C . n 
C 1 163 GLN 163 163 163 GLN GLN C . n 
C 1 164 VAL 164 164 164 VAL VAL C . n 
C 1 165 TYR 165 165 165 TYR TYR C . n 
C 1 166 TYR 166 166 166 TYR TYR C . n 
C 1 167 ARG 167 167 167 ARG ARG C . n 
C 1 168 PRO 168 168 168 PRO PRO C . n 
C 1 169 VAL 169 169 169 VAL VAL C . n 
C 1 170 ASP 170 170 170 ASP ASP C . n 
C 1 171 GLN 171 171 171 GLN GLN C . n 
C 1 172 TYR 172 172 172 TYR TYR C . n 
C 1 173 ASN 173 173 173 ASN ASN C . n 
C 1 174 ASN 174 174 174 ASN ASN C . n 
C 1 175 GLN 175 175 175 GLN GLN C . n 
C 1 176 ASN 176 176 176 ASN ASN C . n 
C 1 177 THR 177 177 177 THR THR C . n 
C 1 178 PHE 178 178 178 PHE PHE C . n 
C 1 179 VAL 179 179 179 VAL VAL C . n 
C 1 180 HIS 180 180 180 HIS HIS C . n 
C 1 181 ASP 181 181 181 ASP ASP C . n 
C 1 182 CYS 182 182 182 CYS CYS C . n 
C 1 183 VAL 183 183 183 VAL VAL C . n 
C 1 184 ASN 184 184 184 ASN ASN C . n 
C 1 185 ILE 185 185 185 ILE ILE C . n 
C 1 186 THR 186 186 186 THR THR C . n 
C 1 187 VAL 187 187 187 VAL VAL C . n 
C 1 188 LYS 188 188 188 LYS LYS C . n 
C 1 189 GLN 189 189 189 GLN GLN C . n 
C 1 190 HIS 190 190 190 HIS HIS C . n 
C 1 191 THR 191 191 191 THR THR C . n 
C 1 192 VAL 192 192 192 VAL VAL C . n 
C 1 193 THR 193 193 193 THR THR C . n 
C 1 194 THR 194 194 194 THR THR C . n 
C 1 195 THR 195 195 195 THR THR C . n 
C 1 196 THR 196 196 196 THR THR C . n 
C 1 197 LYS 197 197 197 LYS LYS C . n 
C 1 198 GLY 198 198 198 GLY GLY C . n 
C 1 199 GLU 199 199 199 GLU GLU C . n 
C 1 200 ASN 200 200 200 ASN ASN C . n 
C 1 201 PHE 201 201 201 PHE PHE C . n 
C 1 202 THR 202 202 202 THR THR C . n 
C 1 203 GLU 203 203 203 GLU GLU C . n 
C 1 204 THR 204 204 204 THR THR C . n 
C 1 205 ASP 205 205 205 ASP ASP C . n 
C 1 206 ILE 206 206 206 ILE ILE C . n 
C 1 207 LYS 207 207 207 LYS LYS C . n 
C 1 208 MET 208 208 208 MET MET C . n 
C 1 209 MET 209 209 209 MET MET C . n 
C 1 210 GLU 210 210 210 GLU GLU C . n 
C 1 211 ARG 211 211 211 ARG ARG C . n 
C 1 212 VAL 212 212 212 VAL VAL C . n 
C 1 213 VAL 213 213 213 VAL VAL C . n 
C 1 214 GLU 214 214 214 GLU GLU C . n 
C 1 215 GLN 215 215 215 GLN GLN C . n 
C 1 216 MET 216 216 216 MET MET C . n 
C 1 217 CYS 217 217 217 CYS CYS C . n 
C 1 218 ILE 218 218 218 ILE ILE C . n 
C 1 219 THR 219 219 219 THR THR C . n 
C 1 220 GLN 220 220 220 GLN GLN C . n 
C 1 221 TYR 221 221 221 TYR TYR C . n 
C 1 222 GLN 222 222 222 GLN GLN C . n 
C 1 223 ARG 223 223 223 ARG ARG C . n 
C 1 224 GLU 224 224 224 GLU GLU C . n 
C 1 225 SER 225 225 225 SER SER C . n 
C 1 226 GLN 226 226 226 GLN GLN C . n 
C 1 227 ALA 227 227 227 ALA ALA C . n 
C 1 228 TYR 228 228 228 TYR TYR C . n 
C 1 229 TYR 229 229 229 TYR TYR C . n 
C 1 230 GLN 230 230 ?   ?   ?   C . n 
C 1 231 ARG 231 231 ?   ?   ?   C . n 
C 1 232 GLY 232 232 ?   ?   ?   C . n 
C 1 233 ALA 233 233 ?   ?   ?   C . n 
C 1 234 SER 234 234 ?   ?   ?   C . n 
C 1 235 VAL 235 235 ?   ?   ?   C . n 
C 1 236 ILE 236 236 ?   ?   ?   C . n 
C 1 237 LEU 237 237 ?   ?   ?   C . n 
C 1 238 PHE 238 238 ?   ?   ?   C . n 
C 1 239 SER 239 239 ?   ?   ?   C . n 
C 1 240 SER 240 240 ?   ?   ?   C . n 
C 1 241 PRO 241 241 ?   ?   ?   C . n 
C 1 242 PRO 242 242 ?   ?   ?   C . n 
C 1 243 VAL 243 243 ?   ?   ?   C . n 
C 1 244 ILE 244 244 ?   ?   ?   C . n 
C 1 245 LEU 245 245 ?   ?   ?   C . n 
C 1 246 LEU 246 246 ?   ?   ?   C . n 
C 1 247 ILE 247 247 ?   ?   ?   C . n 
C 1 248 SER 248 248 ?   ?   ?   C . n 
C 1 249 PHE 249 249 ?   ?   ?   C . n 
C 1 250 LEU 250 250 ?   ?   ?   C . n 
C 1 251 ILE 251 251 ?   ?   ?   C . n 
C 1 252 PHE 252 252 ?   ?   ?   C . n 
C 1 253 LEU 253 253 ?   ?   ?   C . n 
C 1 254 ILE 254 254 ?   ?   ?   C . n 
C 1 255 VAL 255 255 ?   ?   ?   C . n 
C 1 256 GLY 256 256 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   VAL 2   2   ?   ?   ?   D . n 
D 1 3   LYS 3   3   ?   ?   ?   D . n 
D 1 4   SER 4   4   ?   ?   ?   D . n 
D 1 5   HIS 5   5   ?   ?   ?   D . n 
D 1 6   ILE 6   6   ?   ?   ?   D . n 
D 1 7   GLY 7   7   ?   ?   ?   D . n 
D 1 8   SER 8   8   ?   ?   ?   D . n 
D 1 9   TRP 9   9   ?   ?   ?   D . n 
D 1 10  ILE 10  10  ?   ?   ?   D . n 
D 1 11  LEU 11  11  ?   ?   ?   D . n 
D 1 12  VAL 12  12  ?   ?   ?   D . n 
D 1 13  LEU 13  13  ?   ?   ?   D . n 
D 1 14  PHE 14  14  ?   ?   ?   D . n 
D 1 15  VAL 15  15  ?   ?   ?   D . n 
D 1 16  ALA 16  16  ?   ?   ?   D . n 
D 1 17  MET 17  17  ?   ?   ?   D . n 
D 1 18  TRP 18  18  ?   ?   ?   D . n 
D 1 19  SER 19  19  ?   ?   ?   D . n 
D 1 20  ASP 20  20  ?   ?   ?   D . n 
D 1 21  VAL 21  21  ?   ?   ?   D . n 
D 1 22  GLY 22  22  ?   ?   ?   D . n 
D 1 23  LEU 23  23  ?   ?   ?   D . n 
D 1 24  CYS 24  24  ?   ?   ?   D . n 
D 1 25  LYS 25  25  ?   ?   ?   D . n 
D 1 26  LYS 26  26  ?   ?   ?   D . n 
D 1 27  ARG 27  27  ?   ?   ?   D . n 
D 1 28  PRO 28  28  ?   ?   ?   D . n 
D 1 29  LYS 29  29  ?   ?   ?   D . n 
D 1 30  PRO 30  30  ?   ?   ?   D . n 
D 1 31  GLY 31  31  ?   ?   ?   D . n 
D 1 32  GLY 32  32  ?   ?   ?   D . n 
D 1 33  GLY 33  33  ?   ?   ?   D . n 
D 1 34  TRP 34  34  ?   ?   ?   D . n 
D 1 35  ASN 35  35  ?   ?   ?   D . n 
D 1 36  THR 36  36  ?   ?   ?   D . n 
D 1 37  GLY 37  37  ?   ?   ?   D . n 
D 1 38  GLY 38  38  ?   ?   ?   D . n 
D 1 39  SER 39  39  ?   ?   ?   D . n 
D 1 40  ARG 40  40  ?   ?   ?   D . n 
D 1 41  TYR 41  41  ?   ?   ?   D . n 
D 1 42  PRO 42  42  ?   ?   ?   D . n 
D 1 43  GLY 43  43  ?   ?   ?   D . n 
D 1 44  GLN 44  44  ?   ?   ?   D . n 
D 1 45  GLY 45  45  ?   ?   ?   D . n 
D 1 46  SER 46  46  ?   ?   ?   D . n 
D 1 47  PRO 47  47  ?   ?   ?   D . n 
D 1 48  GLY 48  48  ?   ?   ?   D . n 
D 1 49  GLY 49  49  ?   ?   ?   D . n 
D 1 50  ASN 50  50  ?   ?   ?   D . n 
D 1 51  ARG 51  51  ?   ?   ?   D . n 
D 1 52  TYR 52  52  ?   ?   ?   D . n 
D 1 53  PRO 53  53  ?   ?   ?   D . n 
D 1 54  PRO 54  54  ?   ?   ?   D . n 
D 1 55  GLN 55  55  ?   ?   ?   D . n 
D 1 56  GLY 56  56  ?   ?   ?   D . n 
D 1 57  GLY 57  57  ?   ?   ?   D . n 
D 1 58  GLY 58  58  ?   ?   ?   D . n 
D 1 59  GLY 59  59  ?   ?   ?   D . n 
D 1 60  TRP 60  60  ?   ?   ?   D . n 
D 1 61  GLY 61  61  ?   ?   ?   D . n 
D 1 62  GLN 62  62  ?   ?   ?   D . n 
D 1 63  PRO 63  63  ?   ?   ?   D . n 
D 1 64  HIS 64  64  ?   ?   ?   D . n 
D 1 65  GLY 65  65  ?   ?   ?   D . n 
D 1 66  GLY 66  66  ?   ?   ?   D . n 
D 1 67  GLY 67  67  ?   ?   ?   D . n 
D 1 68  TRP 68  68  ?   ?   ?   D . n 
D 1 69  GLY 69  69  ?   ?   ?   D . n 
D 1 70  GLN 70  70  ?   ?   ?   D . n 
D 1 71  PRO 71  71  ?   ?   ?   D . n 
D 1 72  HIS 72  72  ?   ?   ?   D . n 
D 1 73  GLY 73  73  ?   ?   ?   D . n 
D 1 74  GLY 74  74  ?   ?   ?   D . n 
D 1 75  GLY 75  75  ?   ?   ?   D . n 
D 1 76  TRP 76  76  ?   ?   ?   D . n 
D 1 77  GLY 77  77  ?   ?   ?   D . n 
D 1 78  GLN 78  78  ?   ?   ?   D . n 
D 1 79  PRO 79  79  ?   ?   ?   D . n 
D 1 80  HIS 80  80  ?   ?   ?   D . n 
D 1 81  GLY 81  81  ?   ?   ?   D . n 
D 1 82  GLY 82  82  ?   ?   ?   D . n 
D 1 83  GLY 83  83  ?   ?   ?   D . n 
D 1 84  TRP 84  84  ?   ?   ?   D . n 
D 1 85  GLY 85  85  ?   ?   ?   D . n 
D 1 86  GLN 86  86  ?   ?   ?   D . n 
D 1 87  PRO 87  87  ?   ?   ?   D . n 
D 1 88  HIS 88  88  ?   ?   ?   D . n 
D 1 89  GLY 89  89  ?   ?   ?   D . n 
D 1 90  GLY 90  90  ?   ?   ?   D . n 
D 1 91  GLY 91  91  ?   ?   ?   D . n 
D 1 92  GLY 92  92  92  GLY GLY D . n 
D 1 93  TRP 93  93  93  TRP TRP D . n 
D 1 94  GLY 94  94  94  GLY GLY D . n 
D 1 95  GLN 95  95  95  GLN GLN D . n 
D 1 96  GLY 96  96  96  GLY GLY D . n 
D 1 97  GLY 97  97  97  GLY GLY D . n 
D 1 98  THR 98  98  98  THR THR D . n 
D 1 99  HIS 99  99  99  HIS HIS D . n 
D 1 100 SER 100 100 100 SER SER D . n 
D 1 101 GLN 101 101 101 GLN GLN D . n 
D 1 102 TRP 102 102 102 TRP TRP D . n 
D 1 103 ASN 103 103 103 ASN ASN D . n 
D 1 104 LYS 104 104 104 LYS LYS D . n 
D 1 105 PRO 105 105 105 PRO PRO D . n 
D 1 106 SER 106 106 106 SER SER D . n 
D 1 107 LYS 107 107 107 LYS LYS D . n 
D 1 108 PRO 108 108 108 PRO PRO D . n 
D 1 109 LYS 109 109 109 LYS LYS D . n 
D 1 110 THR 110 110 110 THR THR D . n 
D 1 111 ASN 111 111 111 ASN ASN D . n 
D 1 112 MET 112 112 112 MET MET D . n 
D 1 113 LYS 113 113 113 LYS LYS D . n 
D 1 114 HIS 114 114 114 HIS HIS D . n 
D 1 115 VAL 115 115 115 VAL VAL D . n 
D 1 116 ALA 116 116 116 ALA ALA D . n 
D 1 117 GLY 117 117 117 GLY GLY D . n 
D 1 118 ALA 118 118 118 ALA ALA D . n 
D 1 119 ALA 119 119 119 ALA ALA D . n 
D 1 120 ALA 120 120 120 ALA ALA D . n 
D 1 121 ALA 121 121 121 ALA ALA D . n 
D 1 122 GLY 122 122 122 GLY GLY D . n 
D 1 123 ALA 123 123 123 ALA ALA D . n 
D 1 124 VAL 124 124 124 VAL VAL D . n 
D 1 125 VAL 125 125 125 VAL VAL D . n 
D 1 126 GLY 126 126 126 GLY GLY D . n 
D 1 127 GLY 127 127 127 GLY GLY D . n 
D 1 128 LEU 128 128 128 LEU LEU D . n 
D 1 129 GLY 129 129 129 GLY GLY D . n 
D 1 130 GLY 130 130 130 GLY GLY D . n 
D 1 131 TYR 131 131 131 TYR TYR D . n 
D 1 132 MET 132 132 132 MET MET D . n 
D 1 133 LEU 133 133 133 LEU LEU D . n 
D 1 134 GLY 134 134 134 GLY GLY D . n 
D 1 135 SER 135 135 135 SER SER D . n 
D 1 136 ALA 136 136 136 ALA ALA D . n 
D 1 137 MET 137 137 137 MET MET D . n 
D 1 138 SER 138 138 138 SER SER D . n 
D 1 139 ARG 139 139 139 ARG ARG D . n 
D 1 140 PRO 140 140 140 PRO PRO D . n 
D 1 141 LEU 141 141 141 LEU LEU D . n 
D 1 142 ILE 142 142 142 ILE ILE D . n 
D 1 143 HIS 143 143 143 HIS HIS D . n 
D 1 144 PHE 144 144 144 PHE PHE D . n 
D 1 145 GLY 145 145 145 GLY GLY D . n 
D 1 146 ASN 146 146 146 ASN ASN D . n 
D 1 147 ASP 147 147 147 ASP ASP D . n 
D 1 148 TYR 148 148 148 TYR TYR D . n 
D 1 149 GLU 149 149 149 GLU GLU D . n 
D 1 150 ASP 150 150 150 ASP ASP D . n 
D 1 151 ARG 151 151 151 ARG ARG D . n 
D 1 152 TYR 152 152 152 TYR TYR D . n 
D 1 153 TYR 153 153 153 TYR TYR D . n 
D 1 154 ARG 154 154 154 ARG ARG D . n 
D 1 155 GLU 155 155 155 GLU GLU D . n 
D 1 156 ASN 156 156 156 ASN ASN D . n 
D 1 157 MET 157 157 157 MET MET D . n 
D 1 158 TYR 158 158 158 TYR TYR D . n 
D 1 159 ARG 159 159 159 ARG ARG D . n 
D 1 160 TYR 160 160 160 TYR TYR D . n 
D 1 161 PRO 161 161 161 PRO PRO D . n 
D 1 162 ASN 162 162 162 ASN ASN D . n 
D 1 163 GLN 163 163 163 GLN GLN D . n 
D 1 164 VAL 164 164 164 VAL VAL D . n 
D 1 165 TYR 165 165 165 TYR TYR D . n 
D 1 166 TYR 166 166 166 TYR TYR D . n 
D 1 167 ARG 167 167 167 ARG ARG D . n 
D 1 168 PRO 168 168 168 PRO PRO D . n 
D 1 169 VAL 169 169 169 VAL VAL D . n 
D 1 170 ASP 170 170 170 ASP ASP D . n 
D 1 171 GLN 171 171 171 GLN GLN D . n 
D 1 172 TYR 172 172 172 TYR TYR D . n 
D 1 173 ASN 173 173 173 ASN ASN D . n 
D 1 174 ASN 174 174 174 ASN ASN D . n 
D 1 175 GLN 175 175 175 GLN GLN D . n 
D 1 176 ASN 176 176 176 ASN ASN D . n 
D 1 177 THR 177 177 177 THR THR D . n 
D 1 178 PHE 178 178 178 PHE PHE D . n 
D 1 179 VAL 179 179 179 VAL VAL D . n 
D 1 180 HIS 180 180 180 HIS HIS D . n 
D 1 181 ASP 181 181 181 ASP ASP D . n 
D 1 182 CYS 182 182 182 CYS CYS D . n 
D 1 183 VAL 183 183 183 VAL VAL D . n 
D 1 184 ASN 184 184 184 ASN ASN D . n 
D 1 185 ILE 185 185 185 ILE ILE D . n 
D 1 186 THR 186 186 186 THR THR D . n 
D 1 187 VAL 187 187 187 VAL VAL D . n 
D 1 188 LYS 188 188 188 LYS LYS D . n 
D 1 189 GLN 189 189 189 GLN GLN D . n 
D 1 190 HIS 190 190 190 HIS HIS D . n 
D 1 191 THR 191 191 191 THR THR D . n 
D 1 192 VAL 192 192 192 VAL VAL D . n 
D 1 193 THR 193 193 193 THR THR D . n 
D 1 194 THR 194 194 194 THR THR D . n 
D 1 195 THR 195 195 195 THR THR D . n 
D 1 196 THR 196 196 196 THR THR D . n 
D 1 197 LYS 197 197 197 LYS LYS D . n 
D 1 198 GLY 198 198 198 GLY GLY D . n 
D 1 199 GLU 199 199 199 GLU GLU D . n 
D 1 200 ASN 200 200 200 ASN ASN D . n 
D 1 201 PHE 201 201 201 PHE PHE D . n 
D 1 202 THR 202 202 202 THR THR D . n 
D 1 203 GLU 203 203 203 GLU GLU D . n 
D 1 204 THR 204 204 204 THR THR D . n 
D 1 205 ASP 205 205 205 ASP ASP D . n 
D 1 206 ILE 206 206 206 ILE ILE D . n 
D 1 207 LYS 207 207 207 LYS LYS D . n 
D 1 208 MET 208 208 208 MET MET D . n 
D 1 209 MET 209 209 209 MET MET D . n 
D 1 210 GLU 210 210 210 GLU GLU D . n 
D 1 211 ARG 211 211 211 ARG ARG D . n 
D 1 212 VAL 212 212 212 VAL VAL D . n 
D 1 213 VAL 213 213 213 VAL VAL D . n 
D 1 214 GLU 214 214 214 GLU GLU D . n 
D 1 215 GLN 215 215 215 GLN GLN D . n 
D 1 216 MET 216 216 216 MET MET D . n 
D 1 217 CYS 217 217 217 CYS CYS D . n 
D 1 218 ILE 218 218 218 ILE ILE D . n 
D 1 219 THR 219 219 219 THR THR D . n 
D 1 220 GLN 220 220 220 GLN GLN D . n 
D 1 221 TYR 221 221 221 TYR TYR D . n 
D 1 222 GLN 222 222 222 GLN GLN D . n 
D 1 223 ARG 223 223 223 ARG ARG D . n 
D 1 224 GLU 224 224 224 GLU GLU D . n 
D 1 225 SER 225 225 225 SER SER D . n 
D 1 226 GLN 226 226 226 GLN GLN D . n 
D 1 227 ALA 227 227 227 ALA ALA D . n 
D 1 228 TYR 228 228 228 TYR TYR D . n 
D 1 229 TYR 229 229 229 TYR TYR D . n 
D 1 230 GLN 230 230 ?   ?   ?   D . n 
D 1 231 ARG 231 231 ?   ?   ?   D . n 
D 1 232 GLY 232 232 ?   ?   ?   D . n 
D 1 233 ALA 233 233 ?   ?   ?   D . n 
D 1 234 SER 234 234 ?   ?   ?   D . n 
D 1 235 VAL 235 235 ?   ?   ?   D . n 
D 1 236 ILE 236 236 ?   ?   ?   D . n 
D 1 237 LEU 237 237 ?   ?   ?   D . n 
D 1 238 PHE 238 238 ?   ?   ?   D . n 
D 1 239 SER 239 239 ?   ?   ?   D . n 
D 1 240 SER 240 240 ?   ?   ?   D . n 
D 1 241 PRO 241 241 ?   ?   ?   D . n 
D 1 242 PRO 242 242 ?   ?   ?   D . n 
D 1 243 VAL 243 243 ?   ?   ?   D . n 
D 1 244 ILE 244 244 ?   ?   ?   D . n 
D 1 245 LEU 245 245 ?   ?   ?   D . n 
D 1 246 LEU 246 246 ?   ?   ?   D . n 
D 1 247 ILE 247 247 ?   ?   ?   D . n 
D 1 248 SER 248 248 ?   ?   ?   D . n 
D 1 249 PHE 249 249 ?   ?   ?   D . n 
D 1 250 LEU 250 250 ?   ?   ?   D . n 
D 1 251 ILE 251 251 ?   ?   ?   D . n 
D 1 252 PHE 252 252 ?   ?   ?   D . n 
D 1 253 LEU 253 253 ?   ?   ?   D . n 
D 1 254 ILE 254 254 ?   ?   ?   D . n 
D 1 255 VAL 255 255 ?   ?   ?   D . n 
D 1 256 GLY 256 256 ?   ?   ?   D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   VAL 2   2   ?   ?   ?   E . n 
E 1 3   LYS 3   3   ?   ?   ?   E . n 
E 1 4   SER 4   4   ?   ?   ?   E . n 
E 1 5   HIS 5   5   ?   ?   ?   E . n 
E 1 6   ILE 6   6   ?   ?   ?   E . n 
E 1 7   GLY 7   7   ?   ?   ?   E . n 
E 1 8   SER 8   8   ?   ?   ?   E . n 
E 1 9   TRP 9   9   ?   ?   ?   E . n 
E 1 10  ILE 10  10  ?   ?   ?   E . n 
E 1 11  LEU 11  11  ?   ?   ?   E . n 
E 1 12  VAL 12  12  ?   ?   ?   E . n 
E 1 13  LEU 13  13  ?   ?   ?   E . n 
E 1 14  PHE 14  14  ?   ?   ?   E . n 
E 1 15  VAL 15  15  ?   ?   ?   E . n 
E 1 16  ALA 16  16  ?   ?   ?   E . n 
E 1 17  MET 17  17  ?   ?   ?   E . n 
E 1 18  TRP 18  18  ?   ?   ?   E . n 
E 1 19  SER 19  19  ?   ?   ?   E . n 
E 1 20  ASP 20  20  ?   ?   ?   E . n 
E 1 21  VAL 21  21  ?   ?   ?   E . n 
E 1 22  GLY 22  22  ?   ?   ?   E . n 
E 1 23  LEU 23  23  ?   ?   ?   E . n 
E 1 24  CYS 24  24  ?   ?   ?   E . n 
E 1 25  LYS 25  25  ?   ?   ?   E . n 
E 1 26  LYS 26  26  ?   ?   ?   E . n 
E 1 27  ARG 27  27  ?   ?   ?   E . n 
E 1 28  PRO 28  28  ?   ?   ?   E . n 
E 1 29  LYS 29  29  ?   ?   ?   E . n 
E 1 30  PRO 30  30  ?   ?   ?   E . n 
E 1 31  GLY 31  31  ?   ?   ?   E . n 
E 1 32  GLY 32  32  ?   ?   ?   E . n 
E 1 33  GLY 33  33  ?   ?   ?   E . n 
E 1 34  TRP 34  34  ?   ?   ?   E . n 
E 1 35  ASN 35  35  ?   ?   ?   E . n 
E 1 36  THR 36  36  ?   ?   ?   E . n 
E 1 37  GLY 37  37  ?   ?   ?   E . n 
E 1 38  GLY 38  38  ?   ?   ?   E . n 
E 1 39  SER 39  39  ?   ?   ?   E . n 
E 1 40  ARG 40  40  ?   ?   ?   E . n 
E 1 41  TYR 41  41  ?   ?   ?   E . n 
E 1 42  PRO 42  42  ?   ?   ?   E . n 
E 1 43  GLY 43  43  ?   ?   ?   E . n 
E 1 44  GLN 44  44  ?   ?   ?   E . n 
E 1 45  GLY 45  45  ?   ?   ?   E . n 
E 1 46  SER 46  46  ?   ?   ?   E . n 
E 1 47  PRO 47  47  ?   ?   ?   E . n 
E 1 48  GLY 48  48  ?   ?   ?   E . n 
E 1 49  GLY 49  49  ?   ?   ?   E . n 
E 1 50  ASN 50  50  ?   ?   ?   E . n 
E 1 51  ARG 51  51  ?   ?   ?   E . n 
E 1 52  TYR 52  52  ?   ?   ?   E . n 
E 1 53  PRO 53  53  ?   ?   ?   E . n 
E 1 54  PRO 54  54  ?   ?   ?   E . n 
E 1 55  GLN 55  55  ?   ?   ?   E . n 
E 1 56  GLY 56  56  ?   ?   ?   E . n 
E 1 57  GLY 57  57  ?   ?   ?   E . n 
E 1 58  GLY 58  58  ?   ?   ?   E . n 
E 1 59  GLY 59  59  ?   ?   ?   E . n 
E 1 60  TRP 60  60  ?   ?   ?   E . n 
E 1 61  GLY 61  61  ?   ?   ?   E . n 
E 1 62  GLN 62  62  ?   ?   ?   E . n 
E 1 63  PRO 63  63  ?   ?   ?   E . n 
E 1 64  HIS 64  64  ?   ?   ?   E . n 
E 1 65  GLY 65  65  ?   ?   ?   E . n 
E 1 66  GLY 66  66  ?   ?   ?   E . n 
E 1 67  GLY 67  67  ?   ?   ?   E . n 
E 1 68  TRP 68  68  ?   ?   ?   E . n 
E 1 69  GLY 69  69  ?   ?   ?   E . n 
E 1 70  GLN 70  70  ?   ?   ?   E . n 
E 1 71  PRO 71  71  ?   ?   ?   E . n 
E 1 72  HIS 72  72  ?   ?   ?   E . n 
E 1 73  GLY 73  73  ?   ?   ?   E . n 
E 1 74  GLY 74  74  ?   ?   ?   E . n 
E 1 75  GLY 75  75  ?   ?   ?   E . n 
E 1 76  TRP 76  76  ?   ?   ?   E . n 
E 1 77  GLY 77  77  ?   ?   ?   E . n 
E 1 78  GLN 78  78  ?   ?   ?   E . n 
E 1 79  PRO 79  79  ?   ?   ?   E . n 
E 1 80  HIS 80  80  ?   ?   ?   E . n 
E 1 81  GLY 81  81  ?   ?   ?   E . n 
E 1 82  GLY 82  82  ?   ?   ?   E . n 
E 1 83  GLY 83  83  ?   ?   ?   E . n 
E 1 84  TRP 84  84  ?   ?   ?   E . n 
E 1 85  GLY 85  85  ?   ?   ?   E . n 
E 1 86  GLN 86  86  ?   ?   ?   E . n 
E 1 87  PRO 87  87  ?   ?   ?   E . n 
E 1 88  HIS 88  88  ?   ?   ?   E . n 
E 1 89  GLY 89  89  ?   ?   ?   E . n 
E 1 90  GLY 90  90  ?   ?   ?   E . n 
E 1 91  GLY 91  91  ?   ?   ?   E . n 
E 1 92  GLY 92  92  92  GLY GLY E . n 
E 1 93  TRP 93  93  93  TRP TRP E . n 
E 1 94  GLY 94  94  94  GLY GLY E . n 
E 1 95  GLN 95  95  95  GLN GLN E . n 
E 1 96  GLY 96  96  96  GLY GLY E . n 
E 1 97  GLY 97  97  97  GLY GLY E . n 
E 1 98  THR 98  98  98  THR THR E . n 
E 1 99  HIS 99  99  99  HIS HIS E . n 
E 1 100 SER 100 100 100 SER SER E . n 
E 1 101 GLN 101 101 101 GLN GLN E . n 
E 1 102 TRP 102 102 102 TRP TRP E . n 
E 1 103 ASN 103 103 103 ASN ASN E . n 
E 1 104 LYS 104 104 104 LYS LYS E . n 
E 1 105 PRO 105 105 105 PRO PRO E . n 
E 1 106 SER 106 106 106 SER SER E . n 
E 1 107 LYS 107 107 107 LYS LYS E . n 
E 1 108 PRO 108 108 108 PRO PRO E . n 
E 1 109 LYS 109 109 109 LYS LYS E . n 
E 1 110 THR 110 110 110 THR THR E . n 
E 1 111 ASN 111 111 111 ASN ASN E . n 
E 1 112 MET 112 112 112 MET MET E . n 
E 1 113 LYS 113 113 113 LYS LYS E . n 
E 1 114 HIS 114 114 114 HIS HIS E . n 
E 1 115 VAL 115 115 115 VAL VAL E . n 
E 1 116 ALA 116 116 116 ALA ALA E . n 
E 1 117 GLY 117 117 117 GLY GLY E . n 
E 1 118 ALA 118 118 118 ALA ALA E . n 
E 1 119 ALA 119 119 119 ALA ALA E . n 
E 1 120 ALA 120 120 120 ALA ALA E . n 
E 1 121 ALA 121 121 121 ALA ALA E . n 
E 1 122 GLY 122 122 122 GLY GLY E . n 
E 1 123 ALA 123 123 123 ALA ALA E . n 
E 1 124 VAL 124 124 124 VAL VAL E . n 
E 1 125 VAL 125 125 125 VAL VAL E . n 
E 1 126 GLY 126 126 126 GLY GLY E . n 
E 1 127 GLY 127 127 127 GLY GLY E . n 
E 1 128 LEU 128 128 128 LEU LEU E . n 
E 1 129 GLY 129 129 129 GLY GLY E . n 
E 1 130 GLY 130 130 130 GLY GLY E . n 
E 1 131 TYR 131 131 131 TYR TYR E . n 
E 1 132 MET 132 132 132 MET MET E . n 
E 1 133 LEU 133 133 133 LEU LEU E . n 
E 1 134 GLY 134 134 134 GLY GLY E . n 
E 1 135 SER 135 135 135 SER SER E . n 
E 1 136 ALA 136 136 136 ALA ALA E . n 
E 1 137 MET 137 137 137 MET MET E . n 
E 1 138 SER 138 138 138 SER SER E . n 
E 1 139 ARG 139 139 139 ARG ARG E . n 
E 1 140 PRO 140 140 140 PRO PRO E . n 
E 1 141 LEU 141 141 141 LEU LEU E . n 
E 1 142 ILE 142 142 142 ILE ILE E . n 
E 1 143 HIS 143 143 143 HIS HIS E . n 
E 1 144 PHE 144 144 144 PHE PHE E . n 
E 1 145 GLY 145 145 145 GLY GLY E . n 
E 1 146 ASN 146 146 146 ASN ASN E . n 
E 1 147 ASP 147 147 147 ASP ASP E . n 
E 1 148 TYR 148 148 148 TYR TYR E . n 
E 1 149 GLU 149 149 149 GLU GLU E . n 
E 1 150 ASP 150 150 150 ASP ASP E . n 
E 1 151 ARG 151 151 151 ARG ARG E . n 
E 1 152 TYR 152 152 152 TYR TYR E . n 
E 1 153 TYR 153 153 153 TYR TYR E . n 
E 1 154 ARG 154 154 154 ARG ARG E . n 
E 1 155 GLU 155 155 155 GLU GLU E . n 
E 1 156 ASN 156 156 156 ASN ASN E . n 
E 1 157 MET 157 157 157 MET MET E . n 
E 1 158 TYR 158 158 158 TYR TYR E . n 
E 1 159 ARG 159 159 159 ARG ARG E . n 
E 1 160 TYR 160 160 160 TYR TYR E . n 
E 1 161 PRO 161 161 161 PRO PRO E . n 
E 1 162 ASN 162 162 162 ASN ASN E . n 
E 1 163 GLN 163 163 163 GLN GLN E . n 
E 1 164 VAL 164 164 164 VAL VAL E . n 
E 1 165 TYR 165 165 165 TYR TYR E . n 
E 1 166 TYR 166 166 166 TYR TYR E . n 
E 1 167 ARG 167 167 167 ARG ARG E . n 
E 1 168 PRO 168 168 168 PRO PRO E . n 
E 1 169 VAL 169 169 169 VAL VAL E . n 
E 1 170 ASP 170 170 170 ASP ASP E . n 
E 1 171 GLN 171 171 171 GLN GLN E . n 
E 1 172 TYR 172 172 172 TYR TYR E . n 
E 1 173 ASN 173 173 173 ASN ASN E . n 
E 1 174 ASN 174 174 174 ASN ASN E . n 
E 1 175 GLN 175 175 175 GLN GLN E . n 
E 1 176 ASN 176 176 176 ASN ASN E . n 
E 1 177 THR 177 177 177 THR THR E . n 
E 1 178 PHE 178 178 178 PHE PHE E . n 
E 1 179 VAL 179 179 179 VAL VAL E . n 
E 1 180 HIS 180 180 180 HIS HIS E . n 
E 1 181 ASP 181 181 181 ASP ASP E . n 
E 1 182 CYS 182 182 182 CYS CYS E . n 
E 1 183 VAL 183 183 183 VAL VAL E . n 
E 1 184 ASN 184 184 184 ASN ASN E . n 
E 1 185 ILE 185 185 185 ILE ILE E . n 
E 1 186 THR 186 186 186 THR THR E . n 
E 1 187 VAL 187 187 187 VAL VAL E . n 
E 1 188 LYS 188 188 188 LYS LYS E . n 
E 1 189 GLN 189 189 189 GLN GLN E . n 
E 1 190 HIS 190 190 190 HIS HIS E . n 
E 1 191 THR 191 191 191 THR THR E . n 
E 1 192 VAL 192 192 192 VAL VAL E . n 
E 1 193 THR 193 193 193 THR THR E . n 
E 1 194 THR 194 194 194 THR THR E . n 
E 1 195 THR 195 195 195 THR THR E . n 
E 1 196 THR 196 196 196 THR THR E . n 
E 1 197 LYS 197 197 197 LYS LYS E . n 
E 1 198 GLY 198 198 198 GLY GLY E . n 
E 1 199 GLU 199 199 199 GLU GLU E . n 
E 1 200 ASN 200 200 200 ASN ASN E . n 
E 1 201 PHE 201 201 201 PHE PHE E . n 
E 1 202 THR 202 202 202 THR THR E . n 
E 1 203 GLU 203 203 203 GLU GLU E . n 
E 1 204 THR 204 204 204 THR THR E . n 
E 1 205 ASP 205 205 205 ASP ASP E . n 
E 1 206 ILE 206 206 206 ILE ILE E . n 
E 1 207 LYS 207 207 207 LYS LYS E . n 
E 1 208 MET 208 208 208 MET MET E . n 
E 1 209 MET 209 209 209 MET MET E . n 
E 1 210 GLU 210 210 210 GLU GLU E . n 
E 1 211 ARG 211 211 211 ARG ARG E . n 
E 1 212 VAL 212 212 212 VAL VAL E . n 
E 1 213 VAL 213 213 213 VAL VAL E . n 
E 1 214 GLU 214 214 214 GLU GLU E . n 
E 1 215 GLN 215 215 215 GLN GLN E . n 
E 1 216 MET 216 216 216 MET MET E . n 
E 1 217 CYS 217 217 217 CYS CYS E . n 
E 1 218 ILE 218 218 218 ILE ILE E . n 
E 1 219 THR 219 219 219 THR THR E . n 
E 1 220 GLN 220 220 220 GLN GLN E . n 
E 1 221 TYR 221 221 221 TYR TYR E . n 
E 1 222 GLN 222 222 222 GLN GLN E . n 
E 1 223 ARG 223 223 223 ARG ARG E . n 
E 1 224 GLU 224 224 224 GLU GLU E . n 
E 1 225 SER 225 225 225 SER SER E . n 
E 1 226 GLN 226 226 226 GLN GLN E . n 
E 1 227 ALA 227 227 227 ALA ALA E . n 
E 1 228 TYR 228 228 228 TYR TYR E . n 
E 1 229 TYR 229 229 229 TYR TYR E . n 
E 1 230 GLN 230 230 ?   ?   ?   E . n 
E 1 231 ARG 231 231 ?   ?   ?   E . n 
E 1 232 GLY 232 232 ?   ?   ?   E . n 
E 1 233 ALA 233 233 ?   ?   ?   E . n 
E 1 234 SER 234 234 ?   ?   ?   E . n 
E 1 235 VAL 235 235 ?   ?   ?   E . n 
E 1 236 ILE 236 236 ?   ?   ?   E . n 
E 1 237 LEU 237 237 ?   ?   ?   E . n 
E 1 238 PHE 238 238 ?   ?   ?   E . n 
E 1 239 SER 239 239 ?   ?   ?   E . n 
E 1 240 SER 240 240 ?   ?   ?   E . n 
E 1 241 PRO 241 241 ?   ?   ?   E . n 
E 1 242 PRO 242 242 ?   ?   ?   E . n 
E 1 243 VAL 243 243 ?   ?   ?   E . n 
E 1 244 ILE 244 244 ?   ?   ?   E . n 
E 1 245 LEU 245 245 ?   ?   ?   E . n 
E 1 246 LEU 246 246 ?   ?   ?   E . n 
E 1 247 ILE 247 247 ?   ?   ?   E . n 
E 1 248 SER 248 248 ?   ?   ?   E . n 
E 1 249 PHE 249 249 ?   ?   ?   E . n 
E 1 250 LEU 250 250 ?   ?   ?   E . n 
E 1 251 ILE 251 251 ?   ?   ?   E . n 
E 1 252 PHE 252 252 ?   ?   ?   E . n 
E 1 253 LEU 253 253 ?   ?   ?   E . n 
E 1 254 ILE 254 254 ?   ?   ?   E . n 
E 1 255 VAL 255 255 ?   ?   ?   E . n 
E 1 256 GLY 256 256 ?   ?   ?   E . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DMY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DMY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DMY 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9DMY 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 6828 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.473 ? 9240 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.268 ? 936  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.046 ? 930  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.002 ? 1218 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9DMY 
_struct.title                        'Chronic wasting disease prion fibril' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DMY 
_struct_keywords.text            
;Prion, Chronic Wasting Disease, Deer, Fibril, GPI-anchor, PrP, Infectious, Amyloid, Brain-derived, ex vivo, Prion strain, PROTEIN FIBRIL
;
_struct_keywords.pdbx_keywords   'PROTEIN FIBRIL' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q7JIQ1_ODOVR 
_struct_ref.pdbx_db_accession          Q7JIQ1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPH
GGGWGQPHGGGGWGQGGTHSQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRY
PNQVYYRPVDQYNNQNTFVHDCVNITVKQHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGASVILFSS
PPVILLISFLIFLIVG
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9DMY A 1 ? 256 ? Q7JIQ1 1 ? 256 ? 1 256 
2 1 9DMY B 1 ? 256 ? Q7JIQ1 1 ? 256 ? 1 256 
3 1 9DMY C 1 ? 256 ? Q7JIQ1 1 ? 256 ? 1 256 
4 1 9DMY D 1 ? 256 ? Q7JIQ1 1 ? 256 ? 1 256 
5 1 9DMY E 1 ? 256 ? Q7JIQ1 1 ? 256 ? 1 256 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 182 SG ? ? ? 1_555 A CYS 217 SG ? ? A CYS 182 A CYS 217 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf2 disulf ? ? B CYS 182 SG ? ? ? 1_555 B CYS 217 SG ? ? B CYS 182 B CYS 217 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf3 disulf ? ? C CYS 182 SG ? ? ? 1_555 C CYS 217 SG ? ? C CYS 182 C CYS 217 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf4 disulf ? ? D CYS 182 SG ? ? ? 1_555 D CYS 217 SG ? ? D CYS 182 D CYS 217 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf5 disulf ? ? E CYS 182 SG ? ? ? 1_555 E CYS 217 SG ? ? E CYS 182 E CYS 217 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 182 ? CYS A 217 ? CYS A 182 ? 1_555 CYS A 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 182 ? CYS B 217 ? CYS B 182 ? 1_555 CYS B 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS C 182 ? CYS C 217 ? CYS C 182 ? 1_555 CYS C 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS D 182 ? CYS D 217 ? CYS D 182 ? 1_555 CYS D 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS E 182 ? CYS E 217 ? CYS E 182 ? 1_555 CYS E 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 5 ? 
AA3 ? 5 ? 
AA4 ? 5 ? 
AA5 ? 5 ? 
AA6 ? 5 ? 
AA7 ? 5 ? 
AA8 ? 5 ? 
AA9 ? 5 ? 
AB1 ? 2 ? 
AB2 ? 5 ? 
AB3 ? 5 ? 
AB4 ? 5 ? 
AB5 ? 5 ? 
AB6 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA1 4 5 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
AA2 4 5 ? parallel 
AA3 1 2 ? parallel 
AA3 2 3 ? parallel 
AA3 3 4 ? parallel 
AA3 4 5 ? parallel 
AA4 1 2 ? parallel 
AA4 2 3 ? parallel 
AA4 3 4 ? parallel 
AA4 4 5 ? parallel 
AA5 1 2 ? parallel 
AA5 2 3 ? parallel 
AA5 3 4 ? parallel 
AA5 4 5 ? parallel 
AA6 1 2 ? parallel 
AA6 2 3 ? parallel 
AA6 3 4 ? parallel 
AA6 4 5 ? parallel 
AA7 1 2 ? parallel 
AA7 2 3 ? parallel 
AA7 3 4 ? parallel 
AA7 4 5 ? parallel 
AA8 1 2 ? parallel 
AA8 2 3 ? parallel 
AA8 3 4 ? parallel 
AA8 4 5 ? parallel 
AA9 1 2 ? parallel 
AA9 2 3 ? parallel 
AA9 3 4 ? parallel 
AA9 4 5 ? parallel 
AB1 1 2 ? parallel 
AB2 1 2 ? parallel 
AB2 2 3 ? parallel 
AB2 3 4 ? parallel 
AB2 4 5 ? parallel 
AB3 1 2 ? parallel 
AB3 2 3 ? parallel 
AB3 3 4 ? parallel 
AB3 4 5 ? parallel 
AB4 1 2 ? parallel 
AB4 2 3 ? parallel 
AB4 3 4 ? parallel 
AB4 4 5 ? parallel 
AB5 1 2 ? parallel 
AB5 2 3 ? parallel 
AB5 3 4 ? parallel 
AB5 4 5 ? parallel 
AB6 1 2 ? parallel 
AB6 2 3 ? parallel 
AB6 3 4 ? parallel 
AB6 4 5 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY D 94  ? GLN D 95  ? GLY D 94  GLN D 95  
AA1 2 GLY B 94  ? GLN B 95  ? GLY B 94  GLN B 95  
AA1 3 GLY A 94  ? GLN A 95  ? GLY A 94  GLN A 95  
AA1 4 GLY C 94  ? GLN C 95  ? GLY C 94  GLN C 95  
AA1 5 GLY E 94  ? GLN E 95  ? GLY E 94  GLN E 95  
AA2 1 LYS D 109 ? ASN D 111 ? LYS D 109 ASN D 111 
AA2 2 LYS B 109 ? ASN B 111 ? LYS B 109 ASN B 111 
AA2 3 LYS A 109 ? ASN A 111 ? LYS A 109 ASN A 111 
AA2 4 LYS C 109 ? ASN C 111 ? LYS C 109 ASN C 111 
AA2 5 LYS E 109 ? ASN E 111 ? LYS E 109 ASN E 111 
AA3 1 HIS D 114 ? ALA D 116 ? HIS D 114 ALA D 116 
AA3 2 HIS B 114 ? ALA B 116 ? HIS B 114 ALA B 116 
AA3 3 HIS A 114 ? ALA A 116 ? HIS A 114 ALA A 116 
AA3 4 HIS C 114 ? ALA C 116 ? HIS C 114 ALA C 116 
AA3 5 HIS E 114 ? ALA E 116 ? HIS E 114 ALA E 116 
AA4 1 GLY D 130 ? TYR D 131 ? GLY D 130 TYR D 131 
AA4 2 GLY B 130 ? TYR B 131 ? GLY B 130 TYR B 131 
AA4 3 GLY A 130 ? TYR A 131 ? GLY A 130 TYR A 131 
AA4 4 GLY C 130 ? TYR C 131 ? GLY C 130 TYR C 131 
AA4 5 GLY E 130 ? TYR E 131 ? GLY E 130 TYR E 131 
AA5 1 GLY D 134 ? SER D 138 ? GLY D 134 SER D 138 
AA5 2 GLY B 134 ? SER B 138 ? GLY B 134 SER B 138 
AA5 3 GLY A 134 ? SER A 138 ? GLY A 134 SER A 138 
AA5 4 GLY C 134 ? SER C 138 ? GLY C 134 SER C 138 
AA5 5 GLY E 134 ? SER E 138 ? GLY E 134 SER E 138 
AA6 1 LEU D 141 ? ILE D 142 ? LEU D 141 ILE D 142 
AA6 2 LEU B 141 ? ILE B 142 ? LEU B 141 ILE B 142 
AA6 3 LEU A 141 ? ILE A 142 ? LEU A 141 ILE A 142 
AA6 4 LEU C 141 ? ILE C 142 ? LEU C 141 ILE C 142 
AA6 5 LEU E 141 ? ILE E 142 ? LEU E 141 ILE E 142 
AA7 1 ASP D 147 ? ARG D 154 ? ASP D 147 ARG D 154 
AA7 2 ASP B 147 ? ARG B 154 ? ASP B 147 ARG B 154 
AA7 3 ASP A 147 ? ARG A 154 ? ASP A 147 ARG A 154 
AA7 4 ASP C 147 ? ARG C 154 ? ASP C 147 ARG C 154 
AA7 5 ASP E 147 ? ARG E 154 ? ASP E 147 ARG E 154 
AA8 1 MET D 157 ? ARG D 159 ? MET D 157 ARG D 159 
AA8 2 MET B 157 ? ARG B 159 ? MET B 157 ARG B 159 
AA8 3 MET A 157 ? ARG A 159 ? MET A 157 ARG A 159 
AA8 4 MET C 157 ? ARG C 159 ? MET C 157 ARG C 159 
AA8 5 MET E 157 ? ARG E 159 ? MET E 157 ARG E 159 
AA9 1 VAL D 164 ? TYR D 166 ? VAL D 164 TYR D 166 
AA9 2 VAL B 164 ? TYR B 166 ? VAL B 164 TYR B 166 
AA9 3 VAL A 164 ? TYR A 166 ? VAL A 164 TYR A 166 
AA9 4 VAL C 164 ? TYR C 166 ? VAL C 164 TYR C 166 
AA9 5 VAL E 164 ? TYR E 166 ? VAL E 164 TYR E 166 
AB1 1 VAL A 169 ? GLN A 171 ? VAL A 169 GLN A 171 
AB1 2 VAL C 169 ? GLN C 171 ? VAL C 169 GLN C 171 
AB2 1 THR D 177 ? ASP D 181 ? THR D 177 ASP D 181 
AB2 2 THR B 177 ? ASP B 181 ? THR B 177 ASP B 181 
AB2 3 THR A 177 ? ASP A 181 ? THR A 177 ASP A 181 
AB2 4 THR C 177 ? ASP C 181 ? THR C 177 ASP C 181 
AB2 5 THR E 177 ? ASP E 181 ? THR E 177 ASP E 181 
AB3 1 THR D 186 ? THR D 196 ? THR D 186 THR D 196 
AB3 2 THR B 186 ? THR B 196 ? THR B 186 THR B 196 
AB3 3 THR A 186 ? THR A 196 ? THR A 186 THR A 196 
AB3 4 THR C 186 ? THR C 196 ? THR C 186 THR C 196 
AB3 5 THR E 186 ? THR E 196 ? THR E 186 THR E 196 
AB4 1 THR D 202 ? ILE D 206 ? THR D 202 ILE D 206 
AB4 2 THR B 202 ? ILE B 206 ? THR B 202 ILE B 206 
AB4 3 THR A 202 ? LYS A 207 ? THR A 202 LYS A 207 
AB4 4 THR C 202 ? LYS C 207 ? THR C 202 LYS C 207 
AB4 5 THR E 202 ? ILE E 206 ? THR E 202 ILE E 206 
AB5 1 GLN D 220 ? ARG D 223 ? GLN D 220 ARG D 223 
AB5 2 GLN B 220 ? ARG B 223 ? GLN B 220 ARG B 223 
AB5 3 GLN A 220 ? ARG A 223 ? GLN A 220 ARG A 223 
AB5 4 GLN C 220 ? ARG C 223 ? GLN C 220 ARG C 223 
AB5 5 GLN E 220 ? ARG E 223 ? GLN E 220 ARG E 223 
AB6 1 GLN D 226 ? TYR D 228 ? GLN D 226 TYR D 228 
AB6 2 GLN B 226 ? TYR B 228 ? GLN B 226 TYR B 228 
AB6 3 GLN A 226 ? TYR A 228 ? GLN A 226 TYR A 228 
AB6 4 GLN C 226 ? TYR C 228 ? GLN C 226 TYR C 228 
AB6 5 GLN E 226 ? TYR E 228 ? GLN E 226 TYR E 228 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLY D 94  ? O GLY D 94  N GLN B 95  ? N GLN B 95  
AA1 2 3 O GLY B 94  ? O GLY B 94  N GLN A 95  ? N GLN A 95  
AA1 3 4 N GLY A 94  ? N GLY A 94  O GLN C 95  ? O GLN C 95  
AA1 4 5 N GLY C 94  ? N GLY C 94  O GLN E 95  ? O GLN E 95  
AA2 1 2 O LYS D 109 ? O LYS D 109 N THR B 110 ? N THR B 110 
AA2 2 3 O LYS B 109 ? O LYS B 109 N THR A 110 ? N THR A 110 
AA2 3 4 N LYS A 109 ? N LYS A 109 O THR C 110 ? O THR C 110 
AA2 4 5 N LYS C 109 ? N LYS C 109 O THR E 110 ? O THR E 110 
AA3 1 2 O HIS D 114 ? O HIS D 114 N VAL B 115 ? N VAL B 115 
AA3 2 3 O HIS B 114 ? O HIS B 114 N VAL A 115 ? N VAL A 115 
AA3 3 4 N HIS A 114 ? N HIS A 114 O VAL C 115 ? O VAL C 115 
AA3 4 5 N HIS C 114 ? N HIS C 114 O VAL E 115 ? O VAL E 115 
AA4 1 2 O TYR D 131 ? O TYR D 131 N GLY B 130 ? N GLY B 130 
AA4 2 3 O TYR B 131 ? O TYR B 131 N GLY A 130 ? N GLY A 130 
AA4 3 4 N TYR A 131 ? N TYR A 131 O GLY C 130 ? O GLY C 130 
AA4 4 5 N TYR C 131 ? N TYR C 131 O GLY E 130 ? O GLY E 130 
AA5 1 2 O GLY D 134 ? O GLY D 134 N SER B 135 ? N SER B 135 
AA5 2 3 O GLY B 134 ? O GLY B 134 N SER A 135 ? N SER A 135 
AA5 3 4 N GLY A 134 ? N GLY A 134 O SER C 135 ? O SER C 135 
AA5 4 5 N GLY C 134 ? N GLY C 134 O SER E 135 ? O SER E 135 
AA6 1 2 O LEU D 141 ? O LEU D 141 N ILE B 142 ? N ILE B 142 
AA6 2 3 O LEU B 141 ? O LEU B 141 N ILE A 142 ? N ILE A 142 
AA6 3 4 N LEU A 141 ? N LEU A 141 O ILE C 142 ? O ILE C 142 
AA6 4 5 N LEU C 141 ? N LEU C 141 O ILE E 142 ? O ILE E 142 
AA7 1 2 O TYR D 153 ? O TYR D 153 N ARG B 154 ? N ARG B 154 
AA7 2 3 O TYR B 153 ? O TYR B 153 N ARG A 154 ? N ARG A 154 
AA7 3 4 N TYR A 153 ? N TYR A 153 O ARG C 154 ? O ARG C 154 
AA7 4 5 N TYR C 153 ? N TYR C 153 O ARG E 154 ? O ARG E 154 
AA8 1 2 O TYR D 158 ? O TYR D 158 N ARG B 159 ? N ARG B 159 
AA8 2 3 O TYR B 158 ? O TYR B 158 N ARG A 159 ? N ARG A 159 
AA8 3 4 N TYR A 158 ? N TYR A 158 O ARG C 159 ? O ARG C 159 
AA8 4 5 N TYR C 158 ? N TYR C 158 O ARG E 159 ? O ARG E 159 
AA9 1 2 O VAL D 164 ? O VAL D 164 N TYR B 165 ? N TYR B 165 
AA9 2 3 O VAL B 164 ? O VAL B 164 N TYR A 165 ? N TYR A 165 
AA9 3 4 N VAL A 164 ? N VAL A 164 O TYR C 165 ? O TYR C 165 
AA9 4 5 N VAL C 164 ? N VAL C 164 O TYR E 165 ? O TYR E 165 
AB1 1 2 N ASP A 170 ? N ASP A 170 O VAL C 169 ? O VAL C 169 
AB2 1 2 O THR D 177 ? O THR D 177 N PHE B 178 ? N PHE B 178 
AB2 2 3 O THR B 177 ? O THR B 177 N PHE A 178 ? N PHE A 178 
AB2 3 4 N THR A 177 ? N THR A 177 O PHE C 178 ? O PHE C 178 
AB2 4 5 N THR C 177 ? N THR C 177 O PHE E 178 ? O PHE E 178 
AB3 1 2 O VAL D 187 ? O VAL D 187 N THR B 186 ? N THR B 186 
AB3 2 3 O VAL B 187 ? O VAL B 187 N THR A 186 ? N THR A 186 
AB3 3 4 N VAL A 187 ? N VAL A 187 O THR C 186 ? O THR C 186 
AB3 4 5 N VAL C 187 ? N VAL C 187 O THR E 186 ? O THR E 186 
AB4 1 2 O ASP D 205 ? O ASP D 205 N ILE B 206 ? N ILE B 206 
AB4 2 3 O ASP B 205 ? O ASP B 205 N ILE A 206 ? N ILE A 206 
AB4 3 4 N ASP A 205 ? N ASP A 205 O ILE C 206 ? O ILE C 206 
AB4 4 5 N ASP C 205 ? N ASP C 205 O ILE E 206 ? O ILE E 206 
AB5 1 2 O TYR D 221 ? O TYR D 221 N GLN B 222 ? N GLN B 222 
AB5 2 3 O TYR B 221 ? O TYR B 221 N GLN A 222 ? N GLN A 222 
AB5 3 4 N TYR A 221 ? N TYR A 221 O GLN C 222 ? O GLN C 222 
AB5 4 5 N TYR C 221 ? N TYR C 221 O GLN E 222 ? O GLN E 222 
AB6 1 2 O TYR D 228 ? O TYR D 228 N ALA B 227 ? N ALA B 227 
AB6 2 3 O TYR B 228 ? O TYR B 228 N ALA A 227 ? N ALA A 227 
AB6 3 4 N TYR A 228 ? N TYR A 228 O ALA C 227 ? O ALA C 227 
AB6 4 5 N TYR C 228 ? N TYR C 228 O ALA E 227 ? O ALA E 227 
# 
_pdbx_entry_details.entry_id                   9DMY 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_helical_symmetry.entry_id                  9DMY 
_pdbx_helical_symmetry.number_of_operations      5 
_pdbx_helical_symmetry.rotation_per_n_subunits   -0.2913 
_pdbx_helical_symmetry.rise_per_n_subunits       4.779 
_pdbx_helical_symmetry.n_subunits_divisor        1 
_pdbx_helical_symmetry.dyad_axis                 no 
_pdbx_helical_symmetry.circular_symmetry         1 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9DMY 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'AB INITIO MODEL' 
# 
_em_3d_reconstruction.entry_id                    9DMY 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.8 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               7346 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Naturally occurring chronic wasting disease prion fibril' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9DMY 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9DMY 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              90 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   295 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9DMY 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A VAL 2   ? A VAL 2   
3   1 Y 1 A LYS 3   ? A LYS 3   
4   1 Y 1 A SER 4   ? A SER 4   
5   1 Y 1 A HIS 5   ? A HIS 5   
6   1 Y 1 A ILE 6   ? A ILE 6   
7   1 Y 1 A GLY 7   ? A GLY 7   
8   1 Y 1 A SER 8   ? A SER 8   
9   1 Y 1 A TRP 9   ? A TRP 9   
10  1 Y 1 A ILE 10  ? A ILE 10  
11  1 Y 1 A LEU 11  ? A LEU 11  
12  1 Y 1 A VAL 12  ? A VAL 12  
13  1 Y 1 A LEU 13  ? A LEU 13  
14  1 Y 1 A PHE 14  ? A PHE 14  
15  1 Y 1 A VAL 15  ? A VAL 15  
16  1 Y 1 A ALA 16  ? A ALA 16  
17  1 Y 1 A MET 17  ? A MET 17  
18  1 Y 1 A TRP 18  ? A TRP 18  
19  1 Y 1 A SER 19  ? A SER 19  
20  1 Y 1 A ASP 20  ? A ASP 20  
21  1 Y 1 A VAL 21  ? A VAL 21  
22  1 Y 1 A GLY 22  ? A GLY 22  
23  1 Y 1 A LEU 23  ? A LEU 23  
24  1 Y 1 A CYS 24  ? A CYS 24  
25  1 Y 1 A LYS 25  ? A LYS 25  
26  1 Y 1 A LYS 26  ? A LYS 26  
27  1 Y 1 A ARG 27  ? A ARG 27  
28  1 Y 1 A PRO 28  ? A PRO 28  
29  1 Y 1 A LYS 29  ? A LYS 29  
30  1 Y 1 A PRO 30  ? A PRO 30  
31  1 Y 1 A GLY 31  ? A GLY 31  
32  1 Y 1 A GLY 32  ? A GLY 32  
33  1 Y 1 A GLY 33  ? A GLY 33  
34  1 Y 1 A TRP 34  ? A TRP 34  
35  1 Y 1 A ASN 35  ? A ASN 35  
36  1 Y 1 A THR 36  ? A THR 36  
37  1 Y 1 A GLY 37  ? A GLY 37  
38  1 Y 1 A GLY 38  ? A GLY 38  
39  1 Y 1 A SER 39  ? A SER 39  
40  1 Y 1 A ARG 40  ? A ARG 40  
41  1 Y 1 A TYR 41  ? A TYR 41  
42  1 Y 1 A PRO 42  ? A PRO 42  
43  1 Y 1 A GLY 43  ? A GLY 43  
44  1 Y 1 A GLN 44  ? A GLN 44  
45  1 Y 1 A GLY 45  ? A GLY 45  
46  1 Y 1 A SER 46  ? A SER 46  
47  1 Y 1 A PRO 47  ? A PRO 47  
48  1 Y 1 A GLY 48  ? A GLY 48  
49  1 Y 1 A GLY 49  ? A GLY 49  
50  1 Y 1 A ASN 50  ? A ASN 50  
51  1 Y 1 A ARG 51  ? A ARG 51  
52  1 Y 1 A TYR 52  ? A TYR 52  
53  1 Y 1 A PRO 53  ? A PRO 53  
54  1 Y 1 A PRO 54  ? A PRO 54  
55  1 Y 1 A GLN 55  ? A GLN 55  
56  1 Y 1 A GLY 56  ? A GLY 56  
57  1 Y 1 A GLY 57  ? A GLY 57  
58  1 Y 1 A GLY 58  ? A GLY 58  
59  1 Y 1 A GLY 59  ? A GLY 59  
60  1 Y 1 A TRP 60  ? A TRP 60  
61  1 Y 1 A GLY 61  ? A GLY 61  
62  1 Y 1 A GLN 62  ? A GLN 62  
63  1 Y 1 A PRO 63  ? A PRO 63  
64  1 Y 1 A HIS 64  ? A HIS 64  
65  1 Y 1 A GLY 65  ? A GLY 65  
66  1 Y 1 A GLY 66  ? A GLY 66  
67  1 Y 1 A GLY 67  ? A GLY 67  
68  1 Y 1 A TRP 68  ? A TRP 68  
69  1 Y 1 A GLY 69  ? A GLY 69  
70  1 Y 1 A GLN 70  ? A GLN 70  
71  1 Y 1 A PRO 71  ? A PRO 71  
72  1 Y 1 A HIS 72  ? A HIS 72  
73  1 Y 1 A GLY 73  ? A GLY 73  
74  1 Y 1 A GLY 74  ? A GLY 74  
75  1 Y 1 A GLY 75  ? A GLY 75  
76  1 Y 1 A TRP 76  ? A TRP 76  
77  1 Y 1 A GLY 77  ? A GLY 77  
78  1 Y 1 A GLN 78  ? A GLN 78  
79  1 Y 1 A PRO 79  ? A PRO 79  
80  1 Y 1 A HIS 80  ? A HIS 80  
81  1 Y 1 A GLY 81  ? A GLY 81  
82  1 Y 1 A GLY 82  ? A GLY 82  
83  1 Y 1 A GLY 83  ? A GLY 83  
84  1 Y 1 A TRP 84  ? A TRP 84  
85  1 Y 1 A GLY 85  ? A GLY 85  
86  1 Y 1 A GLN 86  ? A GLN 86  
87  1 Y 1 A PRO 87  ? A PRO 87  
88  1 Y 1 A HIS 88  ? A HIS 88  
89  1 Y 1 A GLY 89  ? A GLY 89  
90  1 Y 1 A GLY 90  ? A GLY 90  
91  1 Y 1 A GLY 91  ? A GLY 91  
92  1 Y 1 A GLN 230 ? A GLN 230 
93  1 Y 1 A ARG 231 ? A ARG 231 
94  1 Y 1 A GLY 232 ? A GLY 232 
95  1 Y 1 A ALA 233 ? A ALA 233 
96  1 Y 1 A SER 234 ? A SER 234 
97  1 Y 1 A VAL 235 ? A VAL 235 
98  1 Y 1 A ILE 236 ? A ILE 236 
99  1 Y 1 A LEU 237 ? A LEU 237 
100 1 Y 1 A PHE 238 ? A PHE 238 
101 1 Y 1 A SER 239 ? A SER 239 
102 1 Y 1 A SER 240 ? A SER 240 
103 1 Y 1 A PRO 241 ? A PRO 241 
104 1 Y 1 A PRO 242 ? A PRO 242 
105 1 Y 1 A VAL 243 ? A VAL 243 
106 1 Y 1 A ILE 244 ? A ILE 244 
107 1 Y 1 A LEU 245 ? A LEU 245 
108 1 Y 1 A LEU 246 ? A LEU 246 
109 1 Y 1 A ILE 247 ? A ILE 247 
110 1 Y 1 A SER 248 ? A SER 248 
111 1 Y 1 A PHE 249 ? A PHE 249 
112 1 Y 1 A LEU 250 ? A LEU 250 
113 1 Y 1 A ILE 251 ? A ILE 251 
114 1 Y 1 A PHE 252 ? A PHE 252 
115 1 Y 1 A LEU 253 ? A LEU 253 
116 1 Y 1 A ILE 254 ? A ILE 254 
117 1 Y 1 A VAL 255 ? A VAL 255 
118 1 Y 1 A GLY 256 ? A GLY 256 
119 1 Y 1 B MET 1   ? B MET 1   
120 1 Y 1 B VAL 2   ? B VAL 2   
121 1 Y 1 B LYS 3   ? B LYS 3   
122 1 Y 1 B SER 4   ? B SER 4   
123 1 Y 1 B HIS 5   ? B HIS 5   
124 1 Y 1 B ILE 6   ? B ILE 6   
125 1 Y 1 B GLY 7   ? B GLY 7   
126 1 Y 1 B SER 8   ? B SER 8   
127 1 Y 1 B TRP 9   ? B TRP 9   
128 1 Y 1 B ILE 10  ? B ILE 10  
129 1 Y 1 B LEU 11  ? B LEU 11  
130 1 Y 1 B VAL 12  ? B VAL 12  
131 1 Y 1 B LEU 13  ? B LEU 13  
132 1 Y 1 B PHE 14  ? B PHE 14  
133 1 Y 1 B VAL 15  ? B VAL 15  
134 1 Y 1 B ALA 16  ? B ALA 16  
135 1 Y 1 B MET 17  ? B MET 17  
136 1 Y 1 B TRP 18  ? B TRP 18  
137 1 Y 1 B SER 19  ? B SER 19  
138 1 Y 1 B ASP 20  ? B ASP 20  
139 1 Y 1 B VAL 21  ? B VAL 21  
140 1 Y 1 B GLY 22  ? B GLY 22  
141 1 Y 1 B LEU 23  ? B LEU 23  
142 1 Y 1 B CYS 24  ? B CYS 24  
143 1 Y 1 B LYS 25  ? B LYS 25  
144 1 Y 1 B LYS 26  ? B LYS 26  
145 1 Y 1 B ARG 27  ? B ARG 27  
146 1 Y 1 B PRO 28  ? B PRO 28  
147 1 Y 1 B LYS 29  ? B LYS 29  
148 1 Y 1 B PRO 30  ? B PRO 30  
149 1 Y 1 B GLY 31  ? B GLY 31  
150 1 Y 1 B GLY 32  ? B GLY 32  
151 1 Y 1 B GLY 33  ? B GLY 33  
152 1 Y 1 B TRP 34  ? B TRP 34  
153 1 Y 1 B ASN 35  ? B ASN 35  
154 1 Y 1 B THR 36  ? B THR 36  
155 1 Y 1 B GLY 37  ? B GLY 37  
156 1 Y 1 B GLY 38  ? B GLY 38  
157 1 Y 1 B SER 39  ? B SER 39  
158 1 Y 1 B ARG 40  ? B ARG 40  
159 1 Y 1 B TYR 41  ? B TYR 41  
160 1 Y 1 B PRO 42  ? B PRO 42  
161 1 Y 1 B GLY 43  ? B GLY 43  
162 1 Y 1 B GLN 44  ? B GLN 44  
163 1 Y 1 B GLY 45  ? B GLY 45  
164 1 Y 1 B SER 46  ? B SER 46  
165 1 Y 1 B PRO 47  ? B PRO 47  
166 1 Y 1 B GLY 48  ? B GLY 48  
167 1 Y 1 B GLY 49  ? B GLY 49  
168 1 Y 1 B ASN 50  ? B ASN 50  
169 1 Y 1 B ARG 51  ? B ARG 51  
170 1 Y 1 B TYR 52  ? B TYR 52  
171 1 Y 1 B PRO 53  ? B PRO 53  
172 1 Y 1 B PRO 54  ? B PRO 54  
173 1 Y 1 B GLN 55  ? B GLN 55  
174 1 Y 1 B GLY 56  ? B GLY 56  
175 1 Y 1 B GLY 57  ? B GLY 57  
176 1 Y 1 B GLY 58  ? B GLY 58  
177 1 Y 1 B GLY 59  ? B GLY 59  
178 1 Y 1 B TRP 60  ? B TRP 60  
179 1 Y 1 B GLY 61  ? B GLY 61  
180 1 Y 1 B GLN 62  ? B GLN 62  
181 1 Y 1 B PRO 63  ? B PRO 63  
182 1 Y 1 B HIS 64  ? B HIS 64  
183 1 Y 1 B GLY 65  ? B GLY 65  
184 1 Y 1 B GLY 66  ? B GLY 66  
185 1 Y 1 B GLY 67  ? B GLY 67  
186 1 Y 1 B TRP 68  ? B TRP 68  
187 1 Y 1 B GLY 69  ? B GLY 69  
188 1 Y 1 B GLN 70  ? B GLN 70  
189 1 Y 1 B PRO 71  ? B PRO 71  
190 1 Y 1 B HIS 72  ? B HIS 72  
191 1 Y 1 B GLY 73  ? B GLY 73  
192 1 Y 1 B GLY 74  ? B GLY 74  
193 1 Y 1 B GLY 75  ? B GLY 75  
194 1 Y 1 B TRP 76  ? B TRP 76  
195 1 Y 1 B GLY 77  ? B GLY 77  
196 1 Y 1 B GLN 78  ? B GLN 78  
197 1 Y 1 B PRO 79  ? B PRO 79  
198 1 Y 1 B HIS 80  ? B HIS 80  
199 1 Y 1 B GLY 81  ? B GLY 81  
200 1 Y 1 B GLY 82  ? B GLY 82  
201 1 Y 1 B GLY 83  ? B GLY 83  
202 1 Y 1 B TRP 84  ? B TRP 84  
203 1 Y 1 B GLY 85  ? B GLY 85  
204 1 Y 1 B GLN 86  ? B GLN 86  
205 1 Y 1 B PRO 87  ? B PRO 87  
206 1 Y 1 B HIS 88  ? B HIS 88  
207 1 Y 1 B GLY 89  ? B GLY 89  
208 1 Y 1 B GLY 90  ? B GLY 90  
209 1 Y 1 B GLY 91  ? B GLY 91  
210 1 Y 1 B GLN 230 ? B GLN 230 
211 1 Y 1 B ARG 231 ? B ARG 231 
212 1 Y 1 B GLY 232 ? B GLY 232 
213 1 Y 1 B ALA 233 ? B ALA 233 
214 1 Y 1 B SER 234 ? B SER 234 
215 1 Y 1 B VAL 235 ? B VAL 235 
216 1 Y 1 B ILE 236 ? B ILE 236 
217 1 Y 1 B LEU 237 ? B LEU 237 
218 1 Y 1 B PHE 238 ? B PHE 238 
219 1 Y 1 B SER 239 ? B SER 239 
220 1 Y 1 B SER 240 ? B SER 240 
221 1 Y 1 B PRO 241 ? B PRO 241 
222 1 Y 1 B PRO 242 ? B PRO 242 
223 1 Y 1 B VAL 243 ? B VAL 243 
224 1 Y 1 B ILE 244 ? B ILE 244 
225 1 Y 1 B LEU 245 ? B LEU 245 
226 1 Y 1 B LEU 246 ? B LEU 246 
227 1 Y 1 B ILE 247 ? B ILE 247 
228 1 Y 1 B SER 248 ? B SER 248 
229 1 Y 1 B PHE 249 ? B PHE 249 
230 1 Y 1 B LEU 250 ? B LEU 250 
231 1 Y 1 B ILE 251 ? B ILE 251 
232 1 Y 1 B PHE 252 ? B PHE 252 
233 1 Y 1 B LEU 253 ? B LEU 253 
234 1 Y 1 B ILE 254 ? B ILE 254 
235 1 Y 1 B VAL 255 ? B VAL 255 
236 1 Y 1 B GLY 256 ? B GLY 256 
237 1 Y 1 C MET 1   ? C MET 1   
238 1 Y 1 C VAL 2   ? C VAL 2   
239 1 Y 1 C LYS 3   ? C LYS 3   
240 1 Y 1 C SER 4   ? C SER 4   
241 1 Y 1 C HIS 5   ? C HIS 5   
242 1 Y 1 C ILE 6   ? C ILE 6   
243 1 Y 1 C GLY 7   ? C GLY 7   
244 1 Y 1 C SER 8   ? C SER 8   
245 1 Y 1 C TRP 9   ? C TRP 9   
246 1 Y 1 C ILE 10  ? C ILE 10  
247 1 Y 1 C LEU 11  ? C LEU 11  
248 1 Y 1 C VAL 12  ? C VAL 12  
249 1 Y 1 C LEU 13  ? C LEU 13  
250 1 Y 1 C PHE 14  ? C PHE 14  
251 1 Y 1 C VAL 15  ? C VAL 15  
252 1 Y 1 C ALA 16  ? C ALA 16  
253 1 Y 1 C MET 17  ? C MET 17  
254 1 Y 1 C TRP 18  ? C TRP 18  
255 1 Y 1 C SER 19  ? C SER 19  
256 1 Y 1 C ASP 20  ? C ASP 20  
257 1 Y 1 C VAL 21  ? C VAL 21  
258 1 Y 1 C GLY 22  ? C GLY 22  
259 1 Y 1 C LEU 23  ? C LEU 23  
260 1 Y 1 C CYS 24  ? C CYS 24  
261 1 Y 1 C LYS 25  ? C LYS 25  
262 1 Y 1 C LYS 26  ? C LYS 26  
263 1 Y 1 C ARG 27  ? C ARG 27  
264 1 Y 1 C PRO 28  ? C PRO 28  
265 1 Y 1 C LYS 29  ? C LYS 29  
266 1 Y 1 C PRO 30  ? C PRO 30  
267 1 Y 1 C GLY 31  ? C GLY 31  
268 1 Y 1 C GLY 32  ? C GLY 32  
269 1 Y 1 C GLY 33  ? C GLY 33  
270 1 Y 1 C TRP 34  ? C TRP 34  
271 1 Y 1 C ASN 35  ? C ASN 35  
272 1 Y 1 C THR 36  ? C THR 36  
273 1 Y 1 C GLY 37  ? C GLY 37  
274 1 Y 1 C GLY 38  ? C GLY 38  
275 1 Y 1 C SER 39  ? C SER 39  
276 1 Y 1 C ARG 40  ? C ARG 40  
277 1 Y 1 C TYR 41  ? C TYR 41  
278 1 Y 1 C PRO 42  ? C PRO 42  
279 1 Y 1 C GLY 43  ? C GLY 43  
280 1 Y 1 C GLN 44  ? C GLN 44  
281 1 Y 1 C GLY 45  ? C GLY 45  
282 1 Y 1 C SER 46  ? C SER 46  
283 1 Y 1 C PRO 47  ? C PRO 47  
284 1 Y 1 C GLY 48  ? C GLY 48  
285 1 Y 1 C GLY 49  ? C GLY 49  
286 1 Y 1 C ASN 50  ? C ASN 50  
287 1 Y 1 C ARG 51  ? C ARG 51  
288 1 Y 1 C TYR 52  ? C TYR 52  
289 1 Y 1 C PRO 53  ? C PRO 53  
290 1 Y 1 C PRO 54  ? C PRO 54  
291 1 Y 1 C GLN 55  ? C GLN 55  
292 1 Y 1 C GLY 56  ? C GLY 56  
293 1 Y 1 C GLY 57  ? C GLY 57  
294 1 Y 1 C GLY 58  ? C GLY 58  
295 1 Y 1 C GLY 59  ? C GLY 59  
296 1 Y 1 C TRP 60  ? C TRP 60  
297 1 Y 1 C GLY 61  ? C GLY 61  
298 1 Y 1 C GLN 62  ? C GLN 62  
299 1 Y 1 C PRO 63  ? C PRO 63  
300 1 Y 1 C HIS 64  ? C HIS 64  
301 1 Y 1 C GLY 65  ? C GLY 65  
302 1 Y 1 C GLY 66  ? C GLY 66  
303 1 Y 1 C GLY 67  ? C GLY 67  
304 1 Y 1 C TRP 68  ? C TRP 68  
305 1 Y 1 C GLY 69  ? C GLY 69  
306 1 Y 1 C GLN 70  ? C GLN 70  
307 1 Y 1 C PRO 71  ? C PRO 71  
308 1 Y 1 C HIS 72  ? C HIS 72  
309 1 Y 1 C GLY 73  ? C GLY 73  
310 1 Y 1 C GLY 74  ? C GLY 74  
311 1 Y 1 C GLY 75  ? C GLY 75  
312 1 Y 1 C TRP 76  ? C TRP 76  
313 1 Y 1 C GLY 77  ? C GLY 77  
314 1 Y 1 C GLN 78  ? C GLN 78  
315 1 Y 1 C PRO 79  ? C PRO 79  
316 1 Y 1 C HIS 80  ? C HIS 80  
317 1 Y 1 C GLY 81  ? C GLY 81  
318 1 Y 1 C GLY 82  ? C GLY 82  
319 1 Y 1 C GLY 83  ? C GLY 83  
320 1 Y 1 C TRP 84  ? C TRP 84  
321 1 Y 1 C GLY 85  ? C GLY 85  
322 1 Y 1 C GLN 86  ? C GLN 86  
323 1 Y 1 C PRO 87  ? C PRO 87  
324 1 Y 1 C HIS 88  ? C HIS 88  
325 1 Y 1 C GLY 89  ? C GLY 89  
326 1 Y 1 C GLY 90  ? C GLY 90  
327 1 Y 1 C GLY 91  ? C GLY 91  
328 1 Y 1 C GLN 230 ? C GLN 230 
329 1 Y 1 C ARG 231 ? C ARG 231 
330 1 Y 1 C GLY 232 ? C GLY 232 
331 1 Y 1 C ALA 233 ? C ALA 233 
332 1 Y 1 C SER 234 ? C SER 234 
333 1 Y 1 C VAL 235 ? C VAL 235 
334 1 Y 1 C ILE 236 ? C ILE 236 
335 1 Y 1 C LEU 237 ? C LEU 237 
336 1 Y 1 C PHE 238 ? C PHE 238 
337 1 Y 1 C SER 239 ? C SER 239 
338 1 Y 1 C SER 240 ? C SER 240 
339 1 Y 1 C PRO 241 ? C PRO 241 
340 1 Y 1 C PRO 242 ? C PRO 242 
341 1 Y 1 C VAL 243 ? C VAL 243 
342 1 Y 1 C ILE 244 ? C ILE 244 
343 1 Y 1 C LEU 245 ? C LEU 245 
344 1 Y 1 C LEU 246 ? C LEU 246 
345 1 Y 1 C ILE 247 ? C ILE 247 
346 1 Y 1 C SER 248 ? C SER 248 
347 1 Y 1 C PHE 249 ? C PHE 249 
348 1 Y 1 C LEU 250 ? C LEU 250 
349 1 Y 1 C ILE 251 ? C ILE 251 
350 1 Y 1 C PHE 252 ? C PHE 252 
351 1 Y 1 C LEU 253 ? C LEU 253 
352 1 Y 1 C ILE 254 ? C ILE 254 
353 1 Y 1 C VAL 255 ? C VAL 255 
354 1 Y 1 C GLY 256 ? C GLY 256 
355 1 Y 1 D MET 1   ? D MET 1   
356 1 Y 1 D VAL 2   ? D VAL 2   
357 1 Y 1 D LYS 3   ? D LYS 3   
358 1 Y 1 D SER 4   ? D SER 4   
359 1 Y 1 D HIS 5   ? D HIS 5   
360 1 Y 1 D ILE 6   ? D ILE 6   
361 1 Y 1 D GLY 7   ? D GLY 7   
362 1 Y 1 D SER 8   ? D SER 8   
363 1 Y 1 D TRP 9   ? D TRP 9   
364 1 Y 1 D ILE 10  ? D ILE 10  
365 1 Y 1 D LEU 11  ? D LEU 11  
366 1 Y 1 D VAL 12  ? D VAL 12  
367 1 Y 1 D LEU 13  ? D LEU 13  
368 1 Y 1 D PHE 14  ? D PHE 14  
369 1 Y 1 D VAL 15  ? D VAL 15  
370 1 Y 1 D ALA 16  ? D ALA 16  
371 1 Y 1 D MET 17  ? D MET 17  
372 1 Y 1 D TRP 18  ? D TRP 18  
373 1 Y 1 D SER 19  ? D SER 19  
374 1 Y 1 D ASP 20  ? D ASP 20  
375 1 Y 1 D VAL 21  ? D VAL 21  
376 1 Y 1 D GLY 22  ? D GLY 22  
377 1 Y 1 D LEU 23  ? D LEU 23  
378 1 Y 1 D CYS 24  ? D CYS 24  
379 1 Y 1 D LYS 25  ? D LYS 25  
380 1 Y 1 D LYS 26  ? D LYS 26  
381 1 Y 1 D ARG 27  ? D ARG 27  
382 1 Y 1 D PRO 28  ? D PRO 28  
383 1 Y 1 D LYS 29  ? D LYS 29  
384 1 Y 1 D PRO 30  ? D PRO 30  
385 1 Y 1 D GLY 31  ? D GLY 31  
386 1 Y 1 D GLY 32  ? D GLY 32  
387 1 Y 1 D GLY 33  ? D GLY 33  
388 1 Y 1 D TRP 34  ? D TRP 34  
389 1 Y 1 D ASN 35  ? D ASN 35  
390 1 Y 1 D THR 36  ? D THR 36  
391 1 Y 1 D GLY 37  ? D GLY 37  
392 1 Y 1 D GLY 38  ? D GLY 38  
393 1 Y 1 D SER 39  ? D SER 39  
394 1 Y 1 D ARG 40  ? D ARG 40  
395 1 Y 1 D TYR 41  ? D TYR 41  
396 1 Y 1 D PRO 42  ? D PRO 42  
397 1 Y 1 D GLY 43  ? D GLY 43  
398 1 Y 1 D GLN 44  ? D GLN 44  
399 1 Y 1 D GLY 45  ? D GLY 45  
400 1 Y 1 D SER 46  ? D SER 46  
401 1 Y 1 D PRO 47  ? D PRO 47  
402 1 Y 1 D GLY 48  ? D GLY 48  
403 1 Y 1 D GLY 49  ? D GLY 49  
404 1 Y 1 D ASN 50  ? D ASN 50  
405 1 Y 1 D ARG 51  ? D ARG 51  
406 1 Y 1 D TYR 52  ? D TYR 52  
407 1 Y 1 D PRO 53  ? D PRO 53  
408 1 Y 1 D PRO 54  ? D PRO 54  
409 1 Y 1 D GLN 55  ? D GLN 55  
410 1 Y 1 D GLY 56  ? D GLY 56  
411 1 Y 1 D GLY 57  ? D GLY 57  
412 1 Y 1 D GLY 58  ? D GLY 58  
413 1 Y 1 D GLY 59  ? D GLY 59  
414 1 Y 1 D TRP 60  ? D TRP 60  
415 1 Y 1 D GLY 61  ? D GLY 61  
416 1 Y 1 D GLN 62  ? D GLN 62  
417 1 Y 1 D PRO 63  ? D PRO 63  
418 1 Y 1 D HIS 64  ? D HIS 64  
419 1 Y 1 D GLY 65  ? D GLY 65  
420 1 Y 1 D GLY 66  ? D GLY 66  
421 1 Y 1 D GLY 67  ? D GLY 67  
422 1 Y 1 D TRP 68  ? D TRP 68  
423 1 Y 1 D GLY 69  ? D GLY 69  
424 1 Y 1 D GLN 70  ? D GLN 70  
425 1 Y 1 D PRO 71  ? D PRO 71  
426 1 Y 1 D HIS 72  ? D HIS 72  
427 1 Y 1 D GLY 73  ? D GLY 73  
428 1 Y 1 D GLY 74  ? D GLY 74  
429 1 Y 1 D GLY 75  ? D GLY 75  
430 1 Y 1 D TRP 76  ? D TRP 76  
431 1 Y 1 D GLY 77  ? D GLY 77  
432 1 Y 1 D GLN 78  ? D GLN 78  
433 1 Y 1 D PRO 79  ? D PRO 79  
434 1 Y 1 D HIS 80  ? D HIS 80  
435 1 Y 1 D GLY 81  ? D GLY 81  
436 1 Y 1 D GLY 82  ? D GLY 82  
437 1 Y 1 D GLY 83  ? D GLY 83  
438 1 Y 1 D TRP 84  ? D TRP 84  
439 1 Y 1 D GLY 85  ? D GLY 85  
440 1 Y 1 D GLN 86  ? D GLN 86  
441 1 Y 1 D PRO 87  ? D PRO 87  
442 1 Y 1 D HIS 88  ? D HIS 88  
443 1 Y 1 D GLY 89  ? D GLY 89  
444 1 Y 1 D GLY 90  ? D GLY 90  
445 1 Y 1 D GLY 91  ? D GLY 91  
446 1 Y 1 D GLN 230 ? D GLN 230 
447 1 Y 1 D ARG 231 ? D ARG 231 
448 1 Y 1 D GLY 232 ? D GLY 232 
449 1 Y 1 D ALA 233 ? D ALA 233 
450 1 Y 1 D SER 234 ? D SER 234 
451 1 Y 1 D VAL 235 ? D VAL 235 
452 1 Y 1 D ILE 236 ? D ILE 236 
453 1 Y 1 D LEU 237 ? D LEU 237 
454 1 Y 1 D PHE 238 ? D PHE 238 
455 1 Y 1 D SER 239 ? D SER 239 
456 1 Y 1 D SER 240 ? D SER 240 
457 1 Y 1 D PRO 241 ? D PRO 241 
458 1 Y 1 D PRO 242 ? D PRO 242 
459 1 Y 1 D VAL 243 ? D VAL 243 
460 1 Y 1 D ILE 244 ? D ILE 244 
461 1 Y 1 D LEU 245 ? D LEU 245 
462 1 Y 1 D LEU 246 ? D LEU 246 
463 1 Y 1 D ILE 247 ? D ILE 247 
464 1 Y 1 D SER 248 ? D SER 248 
465 1 Y 1 D PHE 249 ? D PHE 249 
466 1 Y 1 D LEU 250 ? D LEU 250 
467 1 Y 1 D ILE 251 ? D ILE 251 
468 1 Y 1 D PHE 252 ? D PHE 252 
469 1 Y 1 D LEU 253 ? D LEU 253 
470 1 Y 1 D ILE 254 ? D ILE 254 
471 1 Y 1 D VAL 255 ? D VAL 255 
472 1 Y 1 D GLY 256 ? D GLY 256 
473 1 Y 1 E MET 1   ? E MET 1   
474 1 Y 1 E VAL 2   ? E VAL 2   
475 1 Y 1 E LYS 3   ? E LYS 3   
476 1 Y 1 E SER 4   ? E SER 4   
477 1 Y 1 E HIS 5   ? E HIS 5   
478 1 Y 1 E ILE 6   ? E ILE 6   
479 1 Y 1 E GLY 7   ? E GLY 7   
480 1 Y 1 E SER 8   ? E SER 8   
481 1 Y 1 E TRP 9   ? E TRP 9   
482 1 Y 1 E ILE 10  ? E ILE 10  
483 1 Y 1 E LEU 11  ? E LEU 11  
484 1 Y 1 E VAL 12  ? E VAL 12  
485 1 Y 1 E LEU 13  ? E LEU 13  
486 1 Y 1 E PHE 14  ? E PHE 14  
487 1 Y 1 E VAL 15  ? E VAL 15  
488 1 Y 1 E ALA 16  ? E ALA 16  
489 1 Y 1 E MET 17  ? E MET 17  
490 1 Y 1 E TRP 18  ? E TRP 18  
491 1 Y 1 E SER 19  ? E SER 19  
492 1 Y 1 E ASP 20  ? E ASP 20  
493 1 Y 1 E VAL 21  ? E VAL 21  
494 1 Y 1 E GLY 22  ? E GLY 22  
495 1 Y 1 E LEU 23  ? E LEU 23  
496 1 Y 1 E CYS 24  ? E CYS 24  
497 1 Y 1 E LYS 25  ? E LYS 25  
498 1 Y 1 E LYS 26  ? E LYS 26  
499 1 Y 1 E ARG 27  ? E ARG 27  
500 1 Y 1 E PRO 28  ? E PRO 28  
501 1 Y 1 E LYS 29  ? E LYS 29  
502 1 Y 1 E PRO 30  ? E PRO 30  
503 1 Y 1 E GLY 31  ? E GLY 31  
504 1 Y 1 E GLY 32  ? E GLY 32  
505 1 Y 1 E GLY 33  ? E GLY 33  
506 1 Y 1 E TRP 34  ? E TRP 34  
507 1 Y 1 E ASN 35  ? E ASN 35  
508 1 Y 1 E THR 36  ? E THR 36  
509 1 Y 1 E GLY 37  ? E GLY 37  
510 1 Y 1 E GLY 38  ? E GLY 38  
511 1 Y 1 E SER 39  ? E SER 39  
512 1 Y 1 E ARG 40  ? E ARG 40  
513 1 Y 1 E TYR 41  ? E TYR 41  
514 1 Y 1 E PRO 42  ? E PRO 42  
515 1 Y 1 E GLY 43  ? E GLY 43  
516 1 Y 1 E GLN 44  ? E GLN 44  
517 1 Y 1 E GLY 45  ? E GLY 45  
518 1 Y 1 E SER 46  ? E SER 46  
519 1 Y 1 E PRO 47  ? E PRO 47  
520 1 Y 1 E GLY 48  ? E GLY 48  
521 1 Y 1 E GLY 49  ? E GLY 49  
522 1 Y 1 E ASN 50  ? E ASN 50  
523 1 Y 1 E ARG 51  ? E ARG 51  
524 1 Y 1 E TYR 52  ? E TYR 52  
525 1 Y 1 E PRO 53  ? E PRO 53  
526 1 Y 1 E PRO 54  ? E PRO 54  
527 1 Y 1 E GLN 55  ? E GLN 55  
528 1 Y 1 E GLY 56  ? E GLY 56  
529 1 Y 1 E GLY 57  ? E GLY 57  
530 1 Y 1 E GLY 58  ? E GLY 58  
531 1 Y 1 E GLY 59  ? E GLY 59  
532 1 Y 1 E TRP 60  ? E TRP 60  
533 1 Y 1 E GLY 61  ? E GLY 61  
534 1 Y 1 E GLN 62  ? E GLN 62  
535 1 Y 1 E PRO 63  ? E PRO 63  
536 1 Y 1 E HIS 64  ? E HIS 64  
537 1 Y 1 E GLY 65  ? E GLY 65  
538 1 Y 1 E GLY 66  ? E GLY 66  
539 1 Y 1 E GLY 67  ? E GLY 67  
540 1 Y 1 E TRP 68  ? E TRP 68  
541 1 Y 1 E GLY 69  ? E GLY 69  
542 1 Y 1 E GLN 70  ? E GLN 70  
543 1 Y 1 E PRO 71  ? E PRO 71  
544 1 Y 1 E HIS 72  ? E HIS 72  
545 1 Y 1 E GLY 73  ? E GLY 73  
546 1 Y 1 E GLY 74  ? E GLY 74  
547 1 Y 1 E GLY 75  ? E GLY 75  
548 1 Y 1 E TRP 76  ? E TRP 76  
549 1 Y 1 E GLY 77  ? E GLY 77  
550 1 Y 1 E GLN 78  ? E GLN 78  
551 1 Y 1 E PRO 79  ? E PRO 79  
552 1 Y 1 E HIS 80  ? E HIS 80  
553 1 Y 1 E GLY 81  ? E GLY 81  
554 1 Y 1 E GLY 82  ? E GLY 82  
555 1 Y 1 E GLY 83  ? E GLY 83  
556 1 Y 1 E TRP 84  ? E TRP 84  
557 1 Y 1 E GLY 85  ? E GLY 85  
558 1 Y 1 E GLN 86  ? E GLN 86  
559 1 Y 1 E PRO 87  ? E PRO 87  
560 1 Y 1 E HIS 88  ? E HIS 88  
561 1 Y 1 E GLY 89  ? E GLY 89  
562 1 Y 1 E GLY 90  ? E GLY 90  
563 1 Y 1 E GLY 91  ? E GLY 91  
564 1 Y 1 E GLN 230 ? E GLN 230 
565 1 Y 1 E ARG 231 ? E ARG 231 
566 1 Y 1 E GLY 232 ? E GLY 232 
567 1 Y 1 E ALA 233 ? E ALA 233 
568 1 Y 1 E SER 234 ? E SER 234 
569 1 Y 1 E VAL 235 ? E VAL 235 
570 1 Y 1 E ILE 236 ? E ILE 236 
571 1 Y 1 E LEU 237 ? E LEU 237 
572 1 Y 1 E PHE 238 ? E PHE 238 
573 1 Y 1 E SER 239 ? E SER 239 
574 1 Y 1 E SER 240 ? E SER 240 
575 1 Y 1 E PRO 241 ? E PRO 241 
576 1 Y 1 E PRO 242 ? E PRO 242 
577 1 Y 1 E VAL 243 ? E VAL 243 
578 1 Y 1 E ILE 244 ? E ILE 244 
579 1 Y 1 E LEU 245 ? E LEU 245 
580 1 Y 1 E LEU 246 ? E LEU 246 
581 1 Y 1 E ILE 247 ? E ILE 247 
582 1 Y 1 E SER 248 ? E SER 248 
583 1 Y 1 E PHE 249 ? E PHE 249 
584 1 Y 1 E LEU 250 ? E LEU 250 
585 1 Y 1 E ILE 251 ? E ILE 251 
586 1 Y 1 E PHE 252 ? E PHE 252 
587 1 Y 1 E LEU 253 ? E LEU 253 
588 1 Y 1 E ILE 254 ? E ILE 254 
589 1 Y 1 E VAL 255 ? E VAL 255 
590 1 Y 1 E GLY 256 ? E GLY 256 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-16 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9DMY 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'Chronic wasting disease prion fibril' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9874 
_em_entity_assembly_naturalsource.organism             'Odocoileus virginianus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                Brain 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C1 
_em_helical_entity.angular_rotation_per_subunit   -0.2913 
_em_helical_entity.axial_rise_per_subunit         4.779 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOCONTINUUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   535858 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       'Manual Picking' 1  1 ? ? RELION   ? 
'IMAGE ACQUISITION'        ?                2  ? ? 1 SerialEM ? 
MASKING                    ?                3  ? ? ? ?        ? 
'CTF CORRECTION'           ?                4  1 ? ? CTFFIND  4 
'LAYERLINE INDEXING'       ?                5  ? ? ? ?        ? 
'DIFFRACTION INDEXING'     ?                6  ? ? ? ?        ? 
'MODEL FITTING'            ?                7  ? 1 ? Coot     ? 
OTHER                      ?                8  ? ? ? ?        ? 
'INITIAL EULER ASSIGNMENT' ?                9  1 ? ? ?        ? 
'FINAL EULER ASSIGNMENT'   ?                10 1 ? ? ?        ? 
CLASSIFICATION             ?                11 1 ? ? ?        ? 
RECONSTRUCTION             ?                12 1 ? ? RELION   5 
'PARTICLE SELECTION'       ?                13 ? ? ? ?        ? 
'IMAGE ACQUISITION'        ?                14 ? ? 1 ?        ? 
'CTF CORRECTION'           ?                15 ? ? ? ?        ? 
'INITIAL EULER ASSIGNMENT' ?                16 ? ? ? ?        ? 
'FINAL EULER ASSIGNMENT'   ?                17 ? ? ? ?        ? 
CLASSIFICATION             ?                18 ? ? ? ?        ? 
RECONSTRUCTION             ?                19 ? ? ? ?        ? 
'MODEL REFINEMENT'         ?                20 ? 1 ? PHENIX   ? 
'MODEL FITTING'            ?                21 ? 1 ? Coot     ? 
'MODEL REFINEMENT'         ?                22 ? 1 ? REFMAC   ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9DMY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLY A 1 92  ? 108.531 166.160 152.997 1.00 20.68 ? 92  GLY A N   1 
ATOM 2    C CA  . GLY A 1 92  ? 109.385 165.039 153.340 1.00 21.41 ? 92  GLY A CA  1 
ATOM 3    C C   . GLY A 1 92  ? 110.563 164.876 152.400 1.00 23.11 ? 92  GLY A C   1 
ATOM 4    O O   . GLY A 1 92  ? 110.788 163.798 151.852 1.00 20.48 ? 92  GLY A O   1 
ATOM 5    N N   . TRP A 1 93  ? 111.318 165.955 152.214 1.00 18.12 ? 93  TRP A N   1 
ATOM 6    C CA  . TRP A 1 93  ? 112.471 165.946 151.332 1.00 8.04  ? 93  TRP A CA  1 
ATOM 7    C C   . TRP A 1 93  ? 113.708 165.463 152.086 1.00 13.07 ? 93  TRP A C   1 
ATOM 8    O O   . TRP A 1 93  ? 113.657 165.125 153.271 1.00 20.48 ? 93  TRP A O   1 
ATOM 9    C CB  . TRP A 1 93  ? 112.694 167.334 150.735 1.00 14.88 ? 93  TRP A CB  1 
ATOM 10   C CG  . TRP A 1 93  ? 112.810 168.418 151.763 1.00 13.87 ? 93  TRP A CG  1 
ATOM 11   C CD1 . TRP A 1 93  ? 111.795 169.166 152.282 1.00 14.01 ? 93  TRP A CD1 1 
ATOM 12   C CD2 . TRP A 1 93  ? 114.011 168.875 152.397 1.00 18.34 ? 93  TRP A CD2 1 
ATOM 13   N NE1 . TRP A 1 93  ? 112.288 170.061 153.200 1.00 12.85 ? 93  TRP A NE1 1 
ATOM 14   C CE2 . TRP A 1 93  ? 113.646 169.903 153.288 1.00 14.76 ? 93  TRP A CE2 1 
ATOM 15   C CE3 . TRP A 1 93  ? 115.358 168.516 152.298 1.00 13.41 ? 93  TRP A CE3 1 
ATOM 16   C CZ2 . TRP A 1 93  ? 114.578 170.572 154.077 1.00 16.24 ? 93  TRP A CZ2 1 
ATOM 17   C CZ3 . TRP A 1 93  ? 116.282 169.183 153.080 1.00 16.46 ? 93  TRP A CZ3 1 
ATOM 18   C CH2 . TRP A 1 93  ? 115.888 170.200 153.957 1.00 14.58 ? 93  TRP A CH2 1 
ATOM 19   N N   . GLY A 1 94  ? 114.840 165.429 151.388 1.00 12.32 ? 94  GLY A N   1 
ATOM 20   C CA  . GLY A 1 94  ? 116.078 164.987 151.995 1.00 20.82 ? 94  GLY A CA  1 
ATOM 21   C C   . GLY A 1 94  ? 117.317 165.462 151.266 1.00 1.63  ? 94  GLY A C   1 
ATOM 22   O O   . GLY A 1 94  ? 117.406 165.356 150.040 1.00 6.23  ? 94  GLY A O   1 
ATOM 23   N N   . GLN A 1 95  ? 118.283 165.986 152.012 1.00 3.89  ? 95  GLN A N   1 
ATOM 24   C CA  . GLN A 1 95  ? 119.556 166.430 151.462 1.00 7.12  ? 95  GLN A CA  1 
ATOM 25   C C   . GLN A 1 95  ? 120.657 165.499 151.946 1.00 14.08 ? 95  GLN A C   1 
ATOM 26   O O   . GLN A 1 95  ? 120.800 165.275 153.153 1.00 11.67 ? 95  GLN A O   1 
ATOM 27   C CB  . GLN A 1 95  ? 119.858 167.874 151.870 1.00 20.06 ? 95  GLN A CB  1 
ATOM 28   C CG  . GLN A 1 95  ? 119.208 168.920 150.978 1.00 12.05 ? 95  GLN A CG  1 
ATOM 29   C CD  . GLN A 1 95  ? 119.466 170.335 151.457 1.00 13.50 ? 95  GLN A CD  1 
ATOM 30   O OE1 . GLN A 1 95  ? 119.205 170.668 152.613 1.00 21.18 ? 95  GLN A OE1 1 
ATOM 31   N NE2 . GLN A 1 95  ? 119.980 171.176 150.568 1.00 9.13  ? 95  GLN A NE2 1 
ATOM 32   N N   . GLY A 1 96  ? 121.428 164.959 151.006 1.00 19.23 ? 96  GLY A N   1 
ATOM 33   C CA  . GLY A 1 96  ? 122.474 164.024 151.365 1.00 15.72 ? 96  GLY A CA  1 
ATOM 34   C C   . GLY A 1 96  ? 123.584 164.683 152.162 1.00 11.39 ? 96  GLY A C   1 
ATOM 35   O O   . GLY A 1 96  ? 123.868 165.872 152.021 1.00 15.84 ? 96  GLY A O   1 
ATOM 36   N N   . GLY A 1 97  ? 124.216 163.886 153.020 1.00 26.07 ? 97  GLY A N   1 
ATOM 37   C CA  . GLY A 1 97  ? 125.302 164.397 153.832 1.00 21.87 ? 97  GLY A CA  1 
ATOM 38   C C   . GLY A 1 97  ? 126.493 164.815 152.991 1.00 19.44 ? 97  GLY A C   1 
ATOM 39   O O   . GLY A 1 97  ? 126.811 164.210 151.967 1.00 24.60 ? 97  GLY A O   1 
ATOM 40   N N   . THR A 1 98  ? 127.163 165.870 153.439 1.00 16.16 ? 98  THR A N   1 
ATOM 41   C CA  . THR A 1 98  ? 128.296 166.438 152.724 1.00 20.45 ? 98  THR A CA  1 
ATOM 42   C C   . THR A 1 98  ? 129.592 165.974 153.376 1.00 28.17 ? 98  THR A C   1 
ATOM 43   O O   . THR A 1 98  ? 129.832 166.250 154.556 1.00 24.95 ? 98  THR A O   1 
ATOM 44   C CB  . THR A 1 98  ? 128.227 167.964 152.708 1.00 27.73 ? 98  THR A CB  1 
ATOM 45   O OG1 . THR A 1 98  ? 127.060 168.386 151.991 1.00 34.87 ? 98  THR A OG1 1 
ATOM 46   C CG2 . THR A 1 98  ? 129.461 168.538 152.035 1.00 25.45 ? 98  THR A CG2 1 
ATOM 47   N N   . HIS A 1 99  ? 130.419 165.270 152.608 1.00 29.53 ? 99  HIS A N   1 
ATOM 48   C CA  . HIS A 1 99  ? 131.762 164.873 153.026 1.00 21.77 ? 99  HIS A CA  1 
ATOM 49   C C   . HIS A 1 99  ? 132.733 165.558 152.074 1.00 18.56 ? 99  HIS A C   1 
ATOM 50   O O   . HIS A 1 99  ? 133.184 164.970 151.089 1.00 27.14 ? 99  HIS A O   1 
ATOM 51   C CB  . HIS A 1 99  ? 131.924 163.347 153.014 1.00 23.79 ? 99  HIS A CB  1 
ATOM 52   C CG  . HIS A 1 99  ? 130.820 162.616 153.714 1.00 31.37 ? 99  HIS A CG  1 
ATOM 53   N ND1 . HIS A 1 99  ? 129.551 162.503 153.189 1.00 26.06 ? 99  HIS A ND1 1 
ATOM 54   C CD2 . HIS A 1 99  ? 130.797 161.959 154.897 1.00 33.68 ? 99  HIS A CD2 1 
ATOM 55   C CE1 . HIS A 1 99  ? 128.793 161.809 154.019 1.00 25.46 ? 99  HIS A CE1 1 
ATOM 56   N NE2 . HIS A 1 99  ? 129.525 161.467 155.064 1.00 32.69 ? 99  HIS A NE2 1 
ATOM 57   N N   . SER A 1 100 ? 133.065 166.808 152.382 1.00 24.22 ? 100 SER A N   1 
ATOM 58   C CA  . SER A 1 100 ? 133.840 167.657 151.490 1.00 20.38 ? 100 SER A CA  1 
ATOM 59   C C   . SER A 1 100 ? 135.065 168.188 152.215 1.00 22.99 ? 100 SER A C   1 
ATOM 60   O O   . SER A 1 100 ? 134.998 168.527 153.399 1.00 27.23 ? 100 SER A O   1 
ATOM 61   C CB  . SER A 1 100 ? 132.994 168.823 150.967 1.00 26.48 ? 100 SER A CB  1 
ATOM 62   O OG  . SER A 1 100 ? 132.027 168.372 150.035 1.00 26.03 ? 100 SER A OG  1 
ATOM 63   N N   . GLN A 1 101 ? 136.182 168.263 151.500 1.00 21.79 ? 101 GLN A N   1 
ATOM 64   C CA  . GLN A 1 101 ? 137.437 168.729 152.072 1.00 20.71 ? 101 GLN A CA  1 
ATOM 65   C C   . GLN A 1 101 ? 138.000 169.857 151.224 1.00 10.68 ? 101 GLN A C   1 
ATOM 66   O O   . GLN A 1 101 ? 138.180 169.696 150.015 1.00 30.42 ? 101 GLN A O   1 
ATOM 67   C CB  . GLN A 1 101 ? 138.457 167.589 152.169 1.00 12.44 ? 101 GLN A CB  1 
ATOM 68   C CG  . GLN A 1 101 ? 138.097 166.519 153.186 1.00 10.43 ? 101 GLN A CG  1 
ATOM 69   C CD  . GLN A 1 101 ? 137.153 165.474 152.624 1.00 15.80 ? 101 GLN A CD  1 
ATOM 70   O OE1 . GLN A 1 101 ? 137.206 165.148 151.438 1.00 20.91 ? 101 GLN A OE1 1 
ATOM 71   N NE2 . GLN A 1 101 ? 136.283 164.943 153.474 1.00 23.88 ? 101 GLN A NE2 1 
ATOM 72   N N   . TRP A 1 102 ? 138.282 170.996 151.860 1.00 6.30  ? 102 TRP A N   1 
ATOM 73   C CA  . TRP A 1 102 ? 138.929 172.087 151.139 1.00 1.57  ? 102 TRP A CA  1 
ATOM 74   C C   . TRP A 1 102 ? 140.324 171.697 150.672 1.00 18.29 ? 102 TRP A C   1 
ATOM 75   O O   . TRP A 1 102 ? 140.819 172.233 149.673 1.00 18.74 ? 102 TRP A O   1 
ATOM 76   C CB  . TRP A 1 102 ? 138.990 173.339 152.014 1.00 12.63 ? 102 TRP A CB  1 
ATOM 77   C CG  . TRP A 1 102 ? 139.473 174.551 151.278 1.00 14.90 ? 102 TRP A CG  1 
ATOM 78   C CD1 . TRP A 1 102 ? 140.687 175.158 151.407 1.00 13.41 ? 102 TRP A CD1 1 
ATOM 79   C CD2 . TRP A 1 102 ? 138.754 175.298 150.290 1.00 11.77 ? 102 TRP A CD2 1 
ATOM 80   N NE1 . TRP A 1 102 ? 140.767 176.239 150.564 1.00 9.17  ? 102 TRP A NE1 1 
ATOM 81   C CE2 . TRP A 1 102 ? 139.593 176.346 149.867 1.00 4.61  ? 102 TRP A CE2 1 
ATOM 82   C CE3 . TRP A 1 102 ? 137.480 175.183 149.725 1.00 14.49 ? 102 TRP A CE3 1 
ATOM 83   C CZ2 . TRP A 1 102 ? 139.202 177.273 148.904 1.00 8.88  ? 102 TRP A CZ2 1 
ATOM 84   C CZ3 . TRP A 1 102 ? 137.094 176.104 148.769 1.00 9.74  ? 102 TRP A CZ3 1 
ATOM 85   C CH2 . TRP A 1 102 ? 137.951 177.135 148.369 1.00 9.87  ? 102 TRP A CH2 1 
ATOM 86   N N   . ASN A 1 103 ? 140.969 170.770 151.375 1.00 29.15 ? 103 ASN A N   1 
ATOM 87   C CA  . ASN A 1 103 ? 142.283 170.270 150.981 1.00 19.27 ? 103 ASN A CA  1 
ATOM 88   C C   . ASN A 1 103 ? 142.429 168.868 151.555 1.00 23.02 ? 103 ASN A C   1 
ATOM 89   O O   . ASN A 1 103 ? 142.475 168.701 152.777 1.00 20.73 ? 103 ASN A O   1 
ATOM 90   C CB  . ASN A 1 103 ? 143.395 171.188 151.479 1.00 10.46 ? 103 ASN A CB  1 
ATOM 91   C CG  . ASN A 1 103 ? 144.748 170.831 150.899 1.00 23.51 ? 103 ASN A CG  1 
ATOM 92   O OD1 . ASN A 1 103 ? 144.846 170.357 149.768 1.00 13.51 ? 103 ASN A OD1 1 
ATOM 93   N ND2 . ASN A 1 103 ? 145.802 171.059 151.673 1.00 25.90 ? 103 ASN A ND2 1 
ATOM 94   N N   . LYS A 1 104 ? 142.500 167.867 150.679 1.00 14.47 ? 104 LYS A N   1 
ATOM 95   C CA  . LYS A 1 104 ? 142.610 166.465 151.081 1.00 13.11 ? 104 LYS A CA  1 
ATOM 96   C C   . LYS A 1 104 ? 143.792 165.830 150.362 1.00 21.71 ? 104 LYS A C   1 
ATOM 97   O O   . LYS A 1 104 ? 143.616 165.073 149.397 1.00 26.40 ? 104 LYS A O   1 
ATOM 98   C CB  . LYS A 1 104 ? 141.316 165.703 150.789 1.00 11.00 ? 104 LYS A CB  1 
ATOM 99   C CG  . LYS A 1 104 ? 141.243 164.333 151.442 1.00 14.11 ? 104 LYS A CG  1 
ATOM 100  C CD  . LYS A 1 104 ? 140.053 163.540 150.932 1.00 14.28 ? 104 LYS A CD  1 
ATOM 101  C CE  . LYS A 1 104 ? 140.251 162.049 151.147 1.00 20.12 ? 104 LYS A CE  1 
ATOM 102  N NZ  . LYS A 1 104 ? 140.318 161.698 152.592 1.00 22.75 ? 104 LYS A NZ  1 
ATOM 103  N N   . PRO A 1 105 ? 145.018 166.121 150.801 1.00 27.36 ? 105 PRO A N   1 
ATOM 104  C CA  . PRO A 1 105 ? 146.185 165.454 150.214 1.00 24.88 ? 105 PRO A CA  1 
ATOM 105  C C   . PRO A 1 105 ? 146.514 164.151 150.926 1.00 27.76 ? 105 PRO A C   1 
ATOM 106  O O   . PRO A 1 105 ? 146.655 164.126 152.152 1.00 24.01 ? 105 PRO A O   1 
ATOM 107  C CB  . PRO A 1 105 ? 147.304 166.489 150.382 1.00 20.61 ? 105 PRO A CB  1 
ATOM 108  C CG  . PRO A 1 105 ? 146.836 167.410 151.493 1.00 27.07 ? 105 PRO A CG  1 
ATOM 109  C CD  . PRO A 1 105 ? 145.406 167.090 151.838 1.00 26.96 ? 105 PRO A CD  1 
ATOM 110  N N   . SER A 1 106 ? 146.641 163.066 150.170 1.00 27.43 ? 106 SER A N   1 
ATOM 111  C CA  . SER A 1 106 ? 146.913 161.750 150.730 1.00 26.39 ? 106 SER A CA  1 
ATOM 112  C C   . SER A 1 106 ? 148.386 161.410 150.552 1.00 37.67 ? 106 SER A C   1 
ATOM 113  O O   . SER A 1 106 ? 148.902 161.439 149.431 1.00 36.63 ? 106 SER A O   1 
ATOM 114  C CB  . SER A 1 106 ? 146.040 160.685 150.066 1.00 30.29 ? 106 SER A CB  1 
ATOM 115  O OG  . SER A 1 106 ? 146.130 159.450 150.756 1.00 39.13 ? 106 SER A OG  1 
ATOM 116  N N   . LYS A 1 107 ? 149.050 161.086 151.658 1.00 36.62 ? 107 LYS A N   1 
ATOM 117  C CA  . LYS A 1 107 ? 150.462 160.719 151.672 1.00 32.08 ? 107 LYS A CA  1 
ATOM 118  C C   . LYS A 1 107 ? 151.356 161.706 150.914 1.00 32.37 ? 107 LYS A C   1 
ATOM 119  O O   . LYS A 1 107 ? 152.026 161.327 149.947 1.00 34.11 ? 107 LYS A O   1 
ATOM 120  C CB  . LYS A 1 107 ? 150.648 159.308 151.132 1.00 30.25 ? 107 LYS A CB  1 
ATOM 121  C CG  . LYS A 1 107 ? 149.895 158.239 151.905 1.00 33.37 ? 107 LYS A CG  1 
ATOM 122  C CD  . LYS A 1 107 ? 149.766 156.963 151.091 1.00 33.55 ? 107 LYS A CD  1 
ATOM 123  C CE  . LYS A 1 107 ? 148.874 155.949 151.788 1.00 31.41 ? 107 LYS A CE  1 
ATOM 124  N NZ  . LYS A 1 107 ? 148.741 154.695 150.997 1.00 34.53 ? 107 LYS A NZ  1 
ATOM 125  N N   . PRO A 1 108 ? 151.391 162.981 151.324 1.00 30.95 ? 108 PRO A N   1 
ATOM 126  C CA  . PRO A 1 108 ? 152.309 163.935 150.688 1.00 28.77 ? 108 PRO A CA  1 
ATOM 127  C C   . PRO A 1 108 ? 153.722 163.795 151.232 1.00 36.78 ? 108 PRO A C   1 
ATOM 128  O O   . PRO A 1 108 ? 154.023 164.221 152.352 1.00 43.26 ? 108 PRO A O   1 
ATOM 129  C CB  . PRO A 1 108 ? 151.685 165.294 151.035 1.00 27.38 ? 108 PRO A CB  1 
ATOM 130  C CG  . PRO A 1 108 ? 151.035 165.072 152.346 1.00 28.40 ? 108 PRO A CG  1 
ATOM 131  C CD  . PRO A 1 108 ? 150.618 163.615 152.408 1.00 31.51 ? 108 PRO A CD  1 
ATOM 132  N N   . LYS A 1 109 ? 154.598 163.194 150.432 1.00 33.61 ? 109 LYS A N   1 
ATOM 133  C CA  . LYS A 1 109 ? 156.007 163.038 150.775 1.00 28.35 ? 109 LYS A CA  1 
ATOM 134  C C   . LYS A 1 109 ? 156.777 164.148 150.072 1.00 33.90 ? 109 LYS A C   1 
ATOM 135  O O   . LYS A 1 109 ? 156.898 164.146 148.843 1.00 34.26 ? 109 LYS A O   1 
ATOM 136  C CB  . LYS A 1 109 ? 156.519 161.659 150.367 1.00 23.60 ? 109 LYS A CB  1 
ATOM 137  C CG  . LYS A 1 109 ? 155.965 160.522 151.210 1.00 31.99 ? 109 LYS A CG  1 
ATOM 138  C CD  . LYS A 1 109 ? 156.444 159.171 150.707 1.00 35.40 ? 109 LYS A CD  1 
ATOM 139  C CE  . LYS A 1 109 ? 155.877 158.038 151.547 1.00 33.48 ? 109 LYS A CE  1 
ATOM 140  N NZ  . LYS A 1 109 ? 156.332 156.706 151.064 1.00 38.08 ? 109 LYS A NZ  1 
ATOM 141  N N   . THR A 1 110 ? 157.297 165.093 150.849 1.00 29.95 ? 110 THR A N   1 
ATOM 142  C CA  . THR A 1 110 ? 157.883 166.301 150.291 1.00 29.13 ? 110 THR A CA  1 
ATOM 143  C C   . THR A 1 110 ? 159.208 166.603 150.969 1.00 28.75 ? 110 THR A C   1 
ATOM 144  O O   . THR A 1 110 ? 159.345 166.444 152.185 1.00 36.30 ? 110 THR A O   1 
ATOM 145  C CB  . THR A 1 110 ? 156.936 167.497 150.449 1.00 31.82 ? 110 THR A CB  1 
ATOM 146  O OG1 . THR A 1 110 ? 155.614 167.120 150.046 1.00 34.95 ? 110 THR A OG1 1 
ATOM 147  C CG2 . THR A 1 110 ? 157.404 168.660 149.596 1.00 28.18 ? 110 THR A CG2 1 
ATOM 148  N N   . ASN A 1 111 ? 160.182 167.037 150.173 1.00 32.50 ? 111 ASN A N   1 
ATOM 149  C CA  . ASN A 1 111 ? 161.467 167.508 150.671 1.00 35.76 ? 111 ASN A CA  1 
ATOM 150  C C   . ASN A 1 111 ? 161.707 168.908 150.129 1.00 29.82 ? 111 ASN A C   1 
ATOM 151  O O   . ASN A 1 111 ? 161.699 169.115 148.911 1.00 29.82 ? 111 ASN A O   1 
ATOM 152  C CB  . ASN A 1 111 ? 162.599 166.563 150.262 1.00 31.62 ? 111 ASN A CB  1 
ATOM 153  C CG  . ASN A 1 111 ? 162.505 165.214 150.945 1.00 27.28 ? 111 ASN A CG  1 
ATOM 154  O OD1 . ASN A 1 111 ? 162.903 165.062 152.100 1.00 29.74 ? 111 ASN A OD1 1 
ATOM 155  N ND2 . ASN A 1 111 ? 161.977 164.226 150.234 1.00 31.69 ? 111 ASN A ND2 1 
ATOM 156  N N   . MET A 1 112 ? 161.915 169.864 151.031 1.00 28.87 ? 112 MET A N   1 
ATOM 157  C CA  . MET A 1 112 ? 162.143 171.251 150.655 1.00 20.10 ? 112 MET A CA  1 
ATOM 158  C C   . MET A 1 112 ? 163.063 171.882 151.690 1.00 25.20 ? 112 MET A C   1 
ATOM 159  O O   . MET A 1 112 ? 163.494 171.230 152.644 1.00 30.65 ? 112 MET A O   1 
ATOM 160  C CB  . MET A 1 112 ? 160.821 172.012 150.530 1.00 22.06 ? 112 MET A CB  1 
ATOM 161  C CG  . MET A 1 112 ? 159.914 171.876 151.736 1.00 25.37 ? 112 MET A CG  1 
ATOM 162  S SD  . MET A 1 112 ? 158.236 172.425 151.387 1.00 36.99 ? 112 MET A SD  1 
ATOM 163  C CE  . MET A 1 112 ? 157.382 171.826 152.838 1.00 25.12 ? 112 MET A CE  1 
ATOM 164  N N   . LYS A 1 113 ? 163.383 173.159 151.486 1.00 26.64 ? 113 LYS A N   1 
ATOM 165  C CA  . LYS A 1 113 ? 164.244 173.882 152.415 1.00 29.89 ? 113 LYS A CA  1 
ATOM 166  C C   . LYS A 1 113 ? 163.521 175.039 153.092 1.00 31.54 ? 113 LYS A C   1 
ATOM 167  O O   . LYS A 1 113 ? 163.465 175.084 154.324 1.00 37.97 ? 113 LYS A O   1 
ATOM 168  C CB  . LYS A 1 113 ? 165.502 174.378 151.690 1.00 28.96 ? 113 LYS A CB  1 
ATOM 169  C CG  . LYS A 1 113 ? 166.604 174.855 152.619 1.00 33.46 ? 113 LYS A CG  1 
ATOM 170  C CD  . LYS A 1 113 ? 167.808 175.357 151.842 1.00 31.25 ? 113 LYS A CD  1 
ATOM 171  C CE  . LYS A 1 113 ? 168.813 176.027 152.765 1.00 36.76 ? 113 LYS A CE  1 
ATOM 172  N NZ  . LYS A 1 113 ? 169.944 176.636 152.011 1.00 38.57 ? 113 LYS A NZ  1 
ATOM 173  N N   . HIS A 1 114 ? 162.952 175.972 152.331 1.00 33.67 ? 114 HIS A N   1 
ATOM 174  C CA  . HIS A 1 114 ? 162.367 177.181 152.896 1.00 34.05 ? 114 HIS A CA  1 
ATOM 175  C C   . HIS A 1 114 ? 160.925 177.331 152.440 1.00 31.66 ? 114 HIS A C   1 
ATOM 176  O O   . HIS A 1 114 ? 160.632 177.221 151.245 1.00 37.45 ? 114 HIS A O   1 
ATOM 177  C CB  . HIS A 1 114 ? 163.176 178.419 152.498 1.00 32.62 ? 114 HIS A CB  1 
ATOM 178  C CG  . HIS A 1 114 ? 164.524 178.492 153.145 1.00 30.52 ? 114 HIS A CG  1 
ATOM 179  N ND1 . HIS A 1 114 ? 164.898 177.663 154.180 1.00 31.54 ? 114 HIS A ND1 1 
ATOM 180  C CD2 . HIS A 1 114 ? 165.589 179.292 152.900 1.00 37.57 ? 114 HIS A CD2 1 
ATOM 181  C CE1 . HIS A 1 114 ? 166.133 177.951 154.548 1.00 32.97 ? 114 HIS A CE1 1 
ATOM 182  N NE2 . HIS A 1 114 ? 166.576 178.935 153.786 1.00 41.34 ? 114 HIS A NE2 1 
ATOM 183  N N   . VAL A 1 115 ? 160.033 177.579 153.393 1.00 18.65 ? 115 VAL A N   1 
ATOM 184  C CA  . VAL A 1 115 ? 158.630 177.882 153.120 1.00 20.95 ? 115 VAL A CA  1 
ATOM 185  C C   . VAL A 1 115 ? 158.356 179.241 153.751 1.00 29.71 ? 115 VAL A C   1 
ATOM 186  O O   . VAL A 1 115 ? 158.042 179.336 154.942 1.00 24.09 ? 115 VAL A O   1 
ATOM 187  C CB  . VAL A 1 115 ? 157.681 176.811 153.667 1.00 22.37 ? 115 VAL A CB  1 
ATOM 188  C CG1 . VAL A 1 115 ? 156.271 177.039 153.146 1.00 20.55 ? 115 VAL A CG1 1 
ATOM 189  C CG2 . VAL A 1 115 ? 158.175 175.425 153.297 1.00 21.59 ? 115 VAL A CG2 1 
ATOM 190  N N   . ALA A 1 116 ? 158.475 180.303 152.957 1.00 28.27 ? 116 ALA A N   1 
ATOM 191  C CA  . ALA A 1 116 ? 158.300 181.668 153.436 1.00 19.56 ? 116 ALA A CA  1 
ATOM 192  C C   . ALA A 1 116 ? 157.079 182.280 152.768 1.00 22.30 ? 116 ALA A C   1 
ATOM 193  O O   . ALA A 1 116 ? 157.035 182.398 151.539 1.00 21.11 ? 116 ALA A O   1 
ATOM 194  C CB  . ALA A 1 116 ? 159.544 182.512 153.155 1.00 24.56 ? 116 ALA A CB  1 
ATOM 195  N N   . GLY A 1 117 ? 156.095 182.664 153.575 1.00 23.46 ? 117 GLY A N   1 
ATOM 196  C CA  . GLY A 1 117 ? 154.910 183.331 153.057 1.00 22.14 ? 117 GLY A CA  1 
ATOM 197  C C   . GLY A 1 117 ? 154.146 182.522 152.033 1.00 15.74 ? 117 GLY A C   1 
ATOM 198  O O   . GLY A 1 117 ? 153.589 183.092 151.087 1.00 20.89 ? 117 GLY A O   1 
ATOM 199  N N   . ALA A 1 118 ? 154.085 181.206 152.212 1.00 16.73 ? 118 ALA A N   1 
ATOM 200  C CA  . ALA A 1 118 ? 153.545 180.317 151.195 1.00 17.08 ? 118 ALA A CA  1 
ATOM 201  C C   . ALA A 1 118 ? 152.764 179.201 151.879 1.00 12.57 ? 118 ALA A C   1 
ATOM 202  O O   . ALA A 1 118 ? 152.472 179.258 153.077 1.00 17.19 ? 118 ALA A O   1 
ATOM 203  C CB  . ALA A 1 118 ? 154.673 179.773 150.309 1.00 19.48 ? 118 ALA A CB  1 
ATOM 204  N N   . ALA A 1 119 ? 152.409 178.184 151.099 1.00 15.85 ? 119 ALA A N   1 
ATOM 205  C CA  . ALA A 1 119 ? 151.752 176.991 151.607 1.00 21.52 ? 119 ALA A CA  1 
ATOM 206  C C   . ALA A 1 119 ? 152.407 175.772 150.978 1.00 22.91 ? 119 ALA A C   1 
ATOM 207  O O   . ALA A 1 119 ? 152.715 175.774 149.783 1.00 25.54 ? 119 ALA A O   1 
ATOM 208  C CB  . ALA A 1 119 ? 150.250 176.999 151.305 1.00 26.27 ? 119 ALA A CB  1 
ATOM 209  N N   . ALA A 1 120 ? 152.616 174.735 151.783 1.00 24.69 ? 120 ALA A N   1 
ATOM 210  C CA  . ALA A 1 120 ? 153.292 173.542 151.298 1.00 22.52 ? 120 ALA A CA  1 
ATOM 211  C C   . ALA A 1 120 ? 152.909 172.357 152.171 1.00 20.24 ? 120 ALA A C   1 
ATOM 212  O O   . ALA A 1 120 ? 152.370 172.519 153.269 1.00 15.88 ? 120 ALA A O   1 
ATOM 213  C CB  . ALA A 1 120 ? 154.811 173.732 151.274 1.00 22.31 ? 120 ALA A CB  1 
ATOM 214  N N   . ALA A 1 121 ? 153.197 171.160 151.657 1.00 26.64 ? 121 ALA A N   1 
ATOM 215  C CA  . ALA A 1 121 ? 152.936 169.903 152.360 1.00 20.64 ? 121 ALA A CA  1 
ATOM 216  C C   . ALA A 1 121 ? 151.472 169.786 152.780 1.00 14.52 ? 121 ALA A C   1 
ATOM 217  O O   . ALA A 1 121 ? 151.159 169.365 153.895 1.00 24.01 ? 121 ALA A O   1 
ATOM 218  C CB  . ALA A 1 121 ? 153.865 169.740 153.565 1.00 21.13 ? 121 ALA A CB  1 
ATOM 219  N N   . GLY A 1 122 ? 150.570 170.159 151.877 1.00 16.58 ? 122 GLY A N   1 
ATOM 220  C CA  . GLY A 1 122 ? 149.147 170.030 152.121 1.00 17.78 ? 122 GLY A CA  1 
ATOM 221  C C   . GLY A 1 122 ? 148.618 170.888 153.251 1.00 27.05 ? 122 GLY A C   1 
ATOM 222  O O   . GLY A 1 122 ? 147.852 170.411 154.094 1.00 25.18 ? 122 GLY A O   1 
ATOM 223  N N   . ALA A 1 123 ? 149.012 172.158 153.275 1.00 29.98 ? 123 ALA A N   1 
ATOM 224  C CA  . ALA A 1 123 ? 148.616 173.090 154.319 1.00 17.91 ? 123 ALA A CA  1 
ATOM 225  C C   . ALA A 1 123 ? 147.792 174.221 153.721 1.00 23.11 ? 123 ALA A C   1 
ATOM 226  O O   . ALA A 1 123 ? 148.061 174.675 152.605 1.00 27.15 ? 123 ALA A O   1 
ATOM 227  C CB  . ALA A 1 123 ? 149.842 173.654 155.036 1.00 14.96 ? 123 ALA A CB  1 
ATOM 228  N N   . VAL A 1 124 ? 146.788 174.677 154.467 1.00 22.29 ? 124 VAL A N   1 
ATOM 229  C CA  . VAL A 1 124 ? 145.883 175.731 154.023 1.00 22.66 ? 124 VAL A CA  1 
ATOM 230  C C   . VAL A 1 124 ? 146.189 177.000 154.805 1.00 21.01 ? 124 VAL A C   1 
ATOM 231  O O   . VAL A 1 124 ? 146.195 176.987 156.040 1.00 29.05 ? 124 VAL A O   1 
ATOM 232  C CB  . VAL A 1 124 ? 144.410 175.324 154.198 1.00 12.52 ? 124 VAL A CB  1 
ATOM 233  C CG1 . VAL A 1 124 ? 143.516 176.209 153.348 1.00 22.96 ? 124 VAL A CG1 1 
ATOM 234  C CG2 . VAL A 1 124 ? 144.221 173.864 153.833 1.00 21.31 ? 124 VAL A CG2 1 
ATOM 235  N N   . VAL A 1 125 ? 146.446 178.091 154.090 1.00 23.70 ? 125 VAL A N   1 
ATOM 236  C CA  . VAL A 1 125 ? 146.733 179.383 154.740 1.00 23.30 ? 125 VAL A CA  1 
ATOM 237  C C   . VAL A 1 125 ? 145.396 180.101 154.881 1.00 25.73 ? 125 VAL A C   1 
ATOM 238  O O   . VAL A 1 125 ? 145.012 180.954 154.078 1.00 20.16 ? 125 VAL A O   1 
ATOM 239  C CB  . VAL A 1 125 ? 147.767 180.205 153.967 1.00 15.60 ? 125 VAL A CB  1 
ATOM 240  C CG1 . VAL A 1 125 ? 148.154 181.442 154.761 1.00 18.99 ? 125 VAL A CG1 1 
ATOM 241  C CG2 . VAL A 1 125 ? 148.990 179.365 153.665 1.00 19.98 ? 125 VAL A CG2 1 
ATOM 242  N N   . GLY A 1 126 ? 144.676 179.763 155.945 1.00 32.52 ? 126 GLY A N   1 
ATOM 243  C CA  . GLY A 1 126 ? 143.520 180.542 156.341 1.00 31.95 ? 126 GLY A CA  1 
ATOM 244  C C   . GLY A 1 126 ? 142.205 180.232 155.658 1.00 27.90 ? 126 GLY A C   1 
ATOM 245  O O   . GLY A 1 126 ? 142.108 180.244 154.428 1.00 20.23 ? 126 GLY A O   1 
ATOM 246  N N   . GLY A 1 127 ? 141.180 179.958 156.461 1.00 34.95 ? 127 GLY A N   1 
ATOM 247  C CA  . GLY A 1 127 ? 139.811 179.939 155.987 1.00 24.24 ? 127 GLY A CA  1 
ATOM 248  C C   . GLY A 1 127 ? 139.078 181.153 156.518 1.00 23.88 ? 127 GLY A C   1 
ATOM 249  O O   . GLY A 1 127 ? 138.790 181.227 157.716 1.00 26.23 ? 127 GLY A O   1 
ATOM 250  N N   . LEU A 1 128 ? 138.778 182.110 155.637 1.00 28.08 ? 128 LEU A N   1 
ATOM 251  C CA  . LEU A 1 128 ? 138.340 183.447 156.044 1.00 27.75 ? 128 LEU A CA  1 
ATOM 252  C C   . LEU A 1 128 ? 139.353 184.086 156.988 1.00 20.50 ? 128 LEU A C   1 
ATOM 253  O O   . LEU A 1 128 ? 138.994 184.773 157.946 1.00 30.31 ? 128 LEU A O   1 
ATOM 254  C CB  . LEU A 1 128 ? 136.947 183.423 156.676 1.00 24.56 ? 128 LEU A CB  1 
ATOM 255  C CG  . LEU A 1 128 ? 135.763 183.279 155.725 1.00 31.30 ? 128 LEU A CG  1 
ATOM 256  C CD1 . LEU A 1 128 ? 134.488 182.989 156.490 1.00 26.36 ? 128 LEU A CD1 1 
ATOM 257  C CD2 . LEU A 1 128 ? 135.617 184.548 154.918 1.00 31.54 ? 128 LEU A CD2 1 
ATOM 258  N N   . GLY A 1 129 ? 140.633 183.863 156.707 1.00 18.68 ? 129 GLY A N   1 
ATOM 259  C CA  . GLY A 1 129 ? 141.698 184.373 157.544 1.00 20.43 ? 129 GLY A CA  1 
ATOM 260  C C   . GLY A 1 129 ? 143.067 184.135 156.945 1.00 18.98 ? 129 GLY A C   1 
ATOM 261  O O   . GLY A 1 129 ? 143.213 184.067 155.721 1.00 27.51 ? 129 GLY A O   1 
ATOM 262  N N   . GLY A 1 130 ? 144.077 184.005 157.798 1.00 18.01 ? 130 GLY A N   1 
ATOM 263  C CA  . GLY A 1 130 ? 145.434 183.811 157.334 1.00 18.72 ? 130 GLY A CA  1 
ATOM 264  C C   . GLY A 1 130 ? 146.356 184.914 157.804 1.00 22.00 ? 130 GLY A C   1 
ATOM 265  O O   . GLY A 1 130 ? 146.603 185.056 159.005 1.00 23.80 ? 130 GLY A O   1 
ATOM 266  N N   . TYR A 1 131 ? 146.869 185.704 156.867 1.00 36.73 ? 131 TYR A N   1 
ATOM 267  C CA  . TYR A 1 131 ? 147.717 186.852 157.174 1.00 37.70 ? 131 TYR A CA  1 
ATOM 268  C C   . TYR A 1 131 ? 146.975 188.088 156.679 1.00 35.99 ? 131 TYR A C   1 
ATOM 269  O O   . TYR A 1 131 ? 147.187 188.552 155.556 1.00 30.29 ? 131 TYR A O   1 
ATOM 270  C CB  . TYR A 1 131 ? 149.098 186.704 156.541 1.00 31.46 ? 131 TYR A CB  1 
ATOM 271  C CG  . TYR A 1 131 ? 149.932 185.636 157.210 1.00 33.10 ? 131 TYR A CG  1 
ATOM 272  C CD1 . TYR A 1 131 ? 149.699 184.291 156.958 1.00 33.66 ? 131 TYR A CD1 1 
ATOM 273  C CD2 . TYR A 1 131 ? 150.934 185.970 158.112 1.00 34.31 ? 131 TYR A CD2 1 
ATOM 274  C CE1 . TYR A 1 131 ? 150.448 183.309 157.572 1.00 29.12 ? 131 TYR A CE1 1 
ATOM 275  C CE2 . TYR A 1 131 ? 151.689 184.993 158.733 1.00 35.75 ? 131 TYR A CE2 1 
ATOM 276  C CZ  . TYR A 1 131 ? 151.440 183.664 158.459 1.00 36.00 ? 131 TYR A CZ  1 
ATOM 277  O OH  . TYR A 1 131 ? 152.183 182.683 159.072 1.00 36.25 ? 131 TYR A OH  1 
ATOM 278  N N   . MET A 1 132 ? 146.101 188.617 157.530 1.00 41.84 ? 132 MET A N   1 
ATOM 279  C CA  . MET A 1 132 ? 145.215 189.727 157.192 1.00 40.74 ? 132 MET A CA  1 
ATOM 280  C C   . MET A 1 132 ? 145.442 190.827 158.224 1.00 36.12 ? 132 MET A C   1 
ATOM 281  O O   . MET A 1 132 ? 144.713 190.923 159.213 1.00 39.09 ? 132 MET A O   1 
ATOM 282  C CB  . MET A 1 132 ? 143.760 189.260 157.165 1.00 38.98 ? 132 MET A CB  1 
ATOM 283  C CG  . MET A 1 132 ? 143.449 188.292 156.033 1.00 34.61 ? 132 MET A CG  1 
ATOM 284  S SD  . MET A 1 132 ? 141.758 187.670 156.065 1.00 52.81 ? 132 MET A SD  1 
ATOM 285  C CE  . MET A 1 132 ? 140.849 189.125 155.561 1.00 46.16 ? 132 MET A CE  1 
ATOM 286  N N   . LEU A 1 133 ? 146.447 191.670 157.972 1.00 34.63 ? 133 LEU A N   1 
ATOM 287  C CA  . LEU A 1 133 ? 146.858 192.665 158.958 1.00 32.27 ? 133 LEU A CA  1 
ATOM 288  C C   . LEU A 1 133 ? 145.722 193.627 159.285 1.00 37.58 ? 133 LEU A C   1 
ATOM 289  O O   . LEU A 1 133 ? 145.381 193.827 160.456 1.00 43.85 ? 133 LEU A O   1 
ATOM 290  C CB  . LEU A 1 133 ? 148.086 193.420 158.444 1.00 37.63 ? 133 LEU A CB  1 
ATOM 291  C CG  . LEU A 1 133 ? 148.808 194.377 159.391 1.00 38.15 ? 133 LEU A CG  1 
ATOM 292  C CD1 . LEU A 1 133 ? 150.293 194.398 159.083 1.00 40.68 ? 133 LEU A CD1 1 
ATOM 293  C CD2 . LEU A 1 133 ? 148.231 195.774 159.259 1.00 41.94 ? 133 LEU A CD2 1 
ATOM 294  N N   . GLY A 1 134 ? 145.126 194.232 158.263 1.00 45.07 ? 134 GLY A N   1 
ATOM 295  C CA  . GLY A 1 134 ? 144.004 195.124 158.475 1.00 39.06 ? 134 GLY A CA  1 
ATOM 296  C C   . GLY A 1 134 ? 142.736 194.601 157.835 1.00 43.64 ? 134 GLY A C   1 
ATOM 297  O O   . GLY A 1 134 ? 142.619 194.582 156.607 1.00 54.53 ? 134 GLY A O   1 
ATOM 298  N N   . SER A 1 135 ? 141.777 194.176 158.653 1.00 27.65 ? 135 SER A N   1 
ATOM 299  C CA  . SER A 1 135 ? 140.555 193.578 158.141 1.00 34.47 ? 135 SER A CA  1 
ATOM 300  C C   . SER A 1 135 ? 139.362 194.072 158.944 1.00 36.67 ? 135 SER A C   1 
ATOM 301  O O   . SER A 1 135 ? 139.485 194.480 160.101 1.00 42.71 ? 135 SER A O   1 
ATOM 302  C CB  . SER A 1 135 ? 140.618 192.046 158.180 1.00 36.98 ? 135 SER A CB  1 
ATOM 303  O OG  . SER A 1 135 ? 139.584 191.476 157.398 1.00 39.23 ? 135 SER A OG  1 
ATOM 304  N N   . ALA A 1 136 ? 138.197 194.031 158.302 1.00 30.93 ? 136 ALA A N   1 
ATOM 305  C CA  . ALA A 1 136 ? 136.939 194.392 158.949 1.00 36.52 ? 136 ALA A CA  1 
ATOM 306  C C   . ALA A 1 136 ? 135.837 193.600 158.264 1.00 37.11 ? 136 ALA A C   1 
ATOM 307  O O   . ALA A 1 136 ? 135.478 193.899 157.121 1.00 46.08 ? 136 ALA A O   1 
ATOM 308  C CB  . ALA A 1 136 ? 136.680 195.893 158.862 1.00 35.70 ? 136 ALA A CB  1 
ATOM 309  N N   . MET A 1 137 ? 135.310 192.589 158.950 1.00 21.54 ? 137 MET A N   1 
ATOM 310  C CA  . MET A 1 137 ? 134.303 191.702 158.387 1.00 27.00 ? 137 MET A CA  1 
ATOM 311  C C   . MET A 1 137 ? 133.044 191.749 159.239 1.00 28.23 ? 137 MET A C   1 
ATOM 312  O O   . MET A 1 137 ? 133.101 191.514 160.449 1.00 31.94 ? 137 MET A O   1 
ATOM 313  C CB  . MET A 1 137 ? 134.831 190.269 158.291 1.00 34.69 ? 137 MET A CB  1 
ATOM 314  C CG  . MET A 1 137 ? 136.129 190.146 157.510 1.00 36.57 ? 137 MET A CG  1 
ATOM 315  S SD  . MET A 1 137 ? 137.099 188.700 157.977 1.00 51.85 ? 137 MET A SD  1 
ATOM 316  C CE  . MET A 1 137 ? 136.070 187.385 157.335 1.00 38.49 ? 137 MET A CE  1 
ATOM 317  N N   . SER A 1 138 ? 131.913 192.041 158.606 1.00 30.76 ? 138 SER A N   1 
ATOM 318  C CA  . SER A 1 138 ? 130.629 192.110 159.290 1.00 23.74 ? 138 SER A CA  1 
ATOM 319  C C   . SER A 1 138 ? 129.891 190.789 159.120 1.00 26.88 ? 138 SER A C   1 
ATOM 320  O O   . SER A 1 138 ? 129.745 190.295 157.997 1.00 34.27 ? 138 SER A O   1 
ATOM 321  C CB  . SER A 1 138 ? 129.782 193.264 158.751 1.00 21.06 ? 138 SER A CB  1 
ATOM 322  O OG  . SER A 1 138 ? 129.438 193.054 157.394 1.00 34.67 ? 138 SER A OG  1 
ATOM 323  N N   . ARG A 1 139 ? 129.427 190.232 160.234 1.00 23.95 ? 139 ARG A N   1 
ATOM 324  C CA  . ARG A 1 139 ? 128.743 188.944 160.264 1.00 24.93 ? 139 ARG A CA  1 
ATOM 325  C C   . ARG A 1 139 ? 129.516 187.842 159.532 1.00 25.46 ? 139 ARG A C   1 
ATOM 326  O O   . ARG A 1 139 ? 129.011 187.258 158.568 1.00 24.13 ? 139 ARG A O   1 
ATOM 327  C CB  . ARG A 1 139 ? 127.334 189.075 159.702 1.00 27.75 ? 139 ARG A CB  1 
ATOM 328  C CG  . ARG A 1 139 ? 126.382 187.979 160.155 1.00 23.96 ? 139 ARG A CG  1 
ATOM 329  C CD  . ARG A 1 139 ? 125.061 188.555 160.628 1.00 27.63 ? 139 ARG A CD  1 
ATOM 330  N NE  . ARG A 1 139 ? 124.162 188.852 159.520 1.00 38.05 ? 139 ARG A NE  1 
ATOM 331  C CZ  . ARG A 1 139 ? 123.263 188.005 159.037 1.00 36.72 ? 139 ARG A CZ  1 
ATOM 332  N NH1 . ARG A 1 139 ? 123.123 186.788 159.537 1.00 34.68 ? 139 ARG A NH1 1 
ATOM 333  N NH2 . ARG A 1 139 ? 122.484 188.388 158.030 1.00 24.54 ? 139 ARG A NH2 1 
ATOM 334  N N   . PRO A 1 140 ? 130.749 187.535 159.962 1.00 30.70 ? 140 PRO A N   1 
ATOM 335  C CA  . PRO A 1 140 ? 131.469 186.409 159.355 1.00 18.23 ? 140 PRO A CA  1 
ATOM 336  C C   . PRO A 1 140 ? 131.091 185.092 160.010 1.00 16.25 ? 140 PRO A C   1 
ATOM 337  O O   . PRO A 1 140 ? 131.288 184.914 161.215 1.00 19.67 ? 140 PRO A O   1 
ATOM 338  C CB  . PRO A 1 140 ? 132.945 186.762 159.592 1.00 16.75 ? 140 PRO A CB  1 
ATOM 339  C CG  . PRO A 1 140 ? 132.950 188.002 160.479 1.00 23.33 ? 140 PRO A CG  1 
ATOM 340  C CD  . PRO A 1 140 ? 131.563 188.191 160.995 1.00 25.51 ? 140 PRO A CD  1 
ATOM 341  N N   . LEU A 1 141 ? 130.549 184.160 159.228 1.00 17.64 ? 141 LEU A N   1 
ATOM 342  C CA  . LEU A 1 141 ? 129.978 182.933 159.765 1.00 12.64 ? 141 LEU A CA  1 
ATOM 343  C C   . LEU A 1 141 ? 130.611 181.721 159.098 1.00 15.71 ? 141 LEU A C   1 
ATOM 344  O O   . LEU A 1 141 ? 130.699 181.657 157.869 1.00 15.27 ? 141 LEU A O   1 
ATOM 345  C CB  . LEU A 1 141 ? 128.457 182.916 159.570 1.00 21.43 ? 141 LEU A CB  1 
ATOM 346  C CG  . LEU A 1 141 ? 127.723 181.582 159.708 1.00 18.81 ? 141 LEU A CG  1 
ATOM 347  C CD1 . LEU A 1 141 ? 127.965 180.959 161.067 1.00 16.87 ? 141 LEU A CD1 1 
ATOM 348  C CD2 . LEU A 1 141 ? 126.234 181.767 159.460 1.00 22.15 ? 141 LEU A CD2 1 
ATOM 349  N N   . ILE A 1 142 ? 131.051 180.767 159.917 1.00 21.87 ? 142 ILE A N   1 
ATOM 350  C CA  . ILE A 1 142 ? 131.539 179.472 159.457 1.00 10.68 ? 142 ILE A CA  1 
ATOM 351  C C   . ILE A 1 142 ? 130.816 178.395 160.252 1.00 15.07 ? 142 ILE A C   1 
ATOM 352  O O   . ILE A 1 142 ? 130.953 178.335 161.479 1.00 28.23 ? 142 ILE A O   1 
ATOM 353  C CB  . ILE A 1 142 ? 133.060 179.325 159.632 1.00 19.51 ? 142 ILE A CB  1 
ATOM 354  C CG1 . ILE A 1 142 ? 133.805 180.366 158.799 1.00 30.02 ? 142 ILE A CG1 1 
ATOM 355  C CG2 . ILE A 1 142 ? 133.507 177.919 159.260 1.00 16.66 ? 142 ILE A CG2 1 
ATOM 356  C CD1 . ILE A 1 142 ? 135.308 180.184 158.800 1.00 17.00 ? 142 ILE A CD1 1 
ATOM 357  N N   . HIS A 1 143 ? 130.055 177.545 159.567 1.00 11.23 ? 143 HIS A N   1 
ATOM 358  C CA  . HIS A 1 143 ? 129.377 176.438 160.239 1.00 19.18 ? 143 HIS A CA  1 
ATOM 359  C C   . HIS A 1 143 ? 129.387 175.209 159.342 1.00 17.52 ? 143 HIS A C   1 
ATOM 360  O O   . HIS A 1 143 ? 128.734 175.189 158.297 1.00 24.83 ? 143 HIS A O   1 
ATOM 361  C CB  . HIS A 1 143 ? 127.951 176.819 160.652 1.00 14.31 ? 143 HIS A CB  1 
ATOM 362  C CG  . HIS A 1 143 ? 127.045 177.192 159.520 1.00 11.13 ? 143 HIS A CG  1 
ATOM 363  N ND1 . HIS A 1 143 ? 127.048 178.444 158.944 1.00 28.99 ? 143 HIS A ND1 1 
ATOM 364  C CD2 . HIS A 1 143 ? 126.072 176.491 158.891 1.00 18.83 ? 143 HIS A CD2 1 
ATOM 365  C CE1 . HIS A 1 143 ? 126.130 178.491 157.995 1.00 19.62 ? 143 HIS A CE1 1 
ATOM 366  N NE2 . HIS A 1 143 ? 125.526 177.319 157.941 1.00 29.50 ? 143 HIS A NE2 1 
ATOM 367  N N   . PHE A 1 144 ? 130.121 174.178 159.759 1.00 14.58 ? 144 PHE A N   1 
ATOM 368  C CA  . PHE A 1 144 ? 130.175 172.948 158.981 1.00 14.97 ? 144 PHE A CA  1 
ATOM 369  C C   . PHE A 1 144 ? 128.855 172.190 159.004 1.00 7.79  ? 144 PHE A C   1 
ATOM 370  O O   . PHE A 1 144 ? 128.589 171.409 158.086 1.00 34.64 ? 144 PHE A O   1 
ATOM 371  C CB  . PHE A 1 144 ? 131.304 172.055 159.493 1.00 18.95 ? 144 PHE A CB  1 
ATOM 372  C CG  . PHE A 1 144 ? 132.664 172.458 158.999 1.00 14.78 ? 144 PHE A CG  1 
ATOM 373  C CD1 . PHE A 1 144 ? 133.283 173.596 159.488 1.00 13.58 ? 144 PHE A CD1 1 
ATOM 374  C CD2 . PHE A 1 144 ? 133.320 171.702 158.043 1.00 15.27 ? 144 PHE A CD2 1 
ATOM 375  C CE1 . PHE A 1 144 ? 134.532 173.970 159.035 1.00 17.23 ? 144 PHE A CE1 1 
ATOM 376  C CE2 . PHE A 1 144 ? 134.571 172.072 157.586 1.00 15.09 ? 144 PHE A CE2 1 
ATOM 377  C CZ  . PHE A 1 144 ? 135.177 173.208 158.082 1.00 15.67 ? 144 PHE A CZ  1 
ATOM 378  N N   . GLY A 1 145 ? 128.022 172.409 160.015 1.00 0.00  ? 145 GLY A N   1 
ATOM 379  C CA  . GLY A 1 145 ? 126.764 171.701 160.111 1.00 9.34  ? 145 GLY A CA  1 
ATOM 380  C C   . GLY A 1 145 ? 125.741 172.186 159.100 1.00 16.15 ? 145 GLY A C   1 
ATOM 381  O O   . GLY A 1 145 ? 125.911 173.195 158.415 1.00 9.66  ? 145 GLY A O   1 
ATOM 382  N N   . ASN A 1 146 ? 124.650 171.430 159.008 1.00 20.42 ? 146 ASN A N   1 
ATOM 383  C CA  . ASN A 1 146 ? 123.566 171.776 158.102 1.00 21.22 ? 146 ASN A CA  1 
ATOM 384  C C   . ASN A 1 146 ? 122.879 173.061 158.550 1.00 19.80 ? 146 ASN A C   1 
ATOM 385  O O   . ASN A 1 146 ? 122.771 173.353 159.744 1.00 22.01 ? 146 ASN A O   1 
ATOM 386  C CB  . ASN A 1 146 ? 122.549 170.638 158.025 1.00 20.35 ? 146 ASN A CB  1 
ATOM 387  C CG  . ASN A 1 146 ? 123.151 169.352 157.500 1.00 25.80 ? 146 ASN A CG  1 
ATOM 388  O OD1 . ASN A 1 146 ? 123.156 169.102 156.295 1.00 25.52 ? 146 ASN A OD1 1 
ATOM 389  N ND2 . ASN A 1 146 ? 123.664 168.526 158.405 1.00 23.77 ? 146 ASN A ND2 1 
ATOM 390  N N   . ASP A 1 147 ? 122.409 173.832 157.573 1.00 24.50 ? 147 ASP A N   1 
ATOM 391  C CA  . ASP A 1 147 ? 121.762 175.113 157.819 1.00 22.90 ? 147 ASP A CA  1 
ATOM 392  C C   . ASP A 1 147 ? 120.317 175.055 157.347 1.00 18.37 ? 147 ASP A C   1 
ATOM 393  O O   . ASP A 1 147 ? 120.043 174.625 156.222 1.00 31.21 ? 147 ASP A O   1 
ATOM 394  C CB  . ASP A 1 147 ? 122.503 176.248 157.109 1.00 21.68 ? 147 ASP A CB  1 
ATOM 395  C CG  . ASP A 1 147 ? 122.156 177.611 157.672 1.00 30.17 ? 147 ASP A CG  1 
ATOM 396  O OD1 . ASP A 1 147 ? 121.516 177.668 158.742 1.00 29.97 ? 147 ASP A OD1 1 
ATOM 397  O OD2 . ASP A 1 147 ? 122.523 178.626 157.044 1.00 38.96 ? 147 ASP A OD2 1 
ATOM 398  N N   . TYR A 1 148 ? 119.400 175.486 158.210 1.00 19.69 ? 148 TYR A N   1 
ATOM 399  C CA  . TYR A 1 148 ? 117.987 175.595 157.876 1.00 22.88 ? 148 TYR A CA  1 
ATOM 400  C C   . TYR A 1 148 ? 117.506 176.987 158.250 1.00 26.71 ? 148 TYR A C   1 
ATOM 401  O O   . TYR A 1 148 ? 117.755 177.453 159.366 1.00 23.19 ? 148 TYR A O   1 
ATOM 402  C CB  . TYR A 1 148 ? 117.158 174.530 158.602 1.00 16.87 ? 148 TYR A CB  1 
ATOM 403  C CG  . TYR A 1 148 ? 115.704 174.482 158.185 1.00 15.05 ? 148 TYR A CG  1 
ATOM 404  C CD1 . TYR A 1 148 ? 114.764 175.323 158.768 1.00 19.73 ? 148 TYR A CD1 1 
ATOM 405  C CD2 . TYR A 1 148 ? 115.270 173.595 157.210 1.00 19.74 ? 148 TYR A CD2 1 
ATOM 406  C CE1 . TYR A 1 148 ? 113.436 175.280 158.393 1.00 22.95 ? 148 TYR A CE1 1 
ATOM 407  C CE2 . TYR A 1 148 ? 113.943 173.542 156.830 1.00 17.95 ? 148 TYR A CE2 1 
ATOM 408  C CZ  . TYR A 1 148 ? 113.031 174.389 157.423 1.00 19.49 ? 148 TYR A CZ  1 
ATOM 409  O OH  . TYR A 1 148 ? 111.709 174.343 157.046 1.00 24.05 ? 148 TYR A OH  1 
ATOM 410  N N   . GLU A 1 149 ? 116.821 177.647 157.319 1.00 31.72 ? 149 GLU A N   1 
ATOM 411  C CA  . GLU A 1 149 ? 116.303 178.991 157.535 1.00 26.09 ? 149 GLU A CA  1 
ATOM 412  C C   . GLU A 1 149 ? 114.866 179.064 157.045 1.00 25.67 ? 149 GLU A C   1 
ATOM 413  O O   . GLU A 1 149 ? 114.583 178.733 155.889 1.00 34.57 ? 149 GLU A O   1 
ATOM 414  C CB  . GLU A 1 149 ? 117.161 180.039 156.818 1.00 31.89 ? 149 GLU A CB  1 
ATOM 415  C CG  . GLU A 1 149 ? 118.527 180.258 157.445 1.00 36.78 ? 149 GLU A CG  1 
ATOM 416  C CD  . GLU A 1 149 ? 119.297 181.386 156.787 1.00 43.02 ? 149 GLU A CD  1 
ATOM 417  O OE1 . GLU A 1 149 ? 118.700 182.118 155.970 1.00 35.95 ? 149 GLU A OE1 1 
ATOM 418  O OE2 . GLU A 1 149 ? 120.499 181.541 157.087 1.00 47.50 ? 149 GLU A OE2 1 
ATOM 419  N N   . ASP A 1 150 ? 113.965 179.497 157.926 1.00 33.18 ? 150 ASP A N   1 
ATOM 420  C CA  . ASP A 1 150 ? 112.556 179.718 157.597 1.00 28.31 ? 150 ASP A CA  1 
ATOM 421  C C   . ASP A 1 150 ? 112.238 181.155 158.001 1.00 30.42 ? 150 ASP A C   1 
ATOM 422  O O   . ASP A 1 150 ? 111.792 181.411 159.122 1.00 32.11 ? 150 ASP A O   1 
ATOM 423  C CB  . ASP A 1 150 ? 111.655 178.710 158.303 1.00 29.78 ? 150 ASP A CB  1 
ATOM 424  C CG  . ASP A 1 150 ? 110.237 178.724 157.770 1.00 33.97 ? 150 ASP A CG  1 
ATOM 425  O OD1 . ASP A 1 150 ? 109.998 179.366 156.726 1.00 38.41 ? 150 ASP A OD1 1 
ATOM 426  O OD2 . ASP A 1 150 ? 109.360 178.091 158.395 1.00 38.20 ? 150 ASP A OD2 1 
ATOM 427  N N   . ARG A 1 151 ? 112.468 182.088 157.082 1.00 35.19 ? 151 ARG A N   1 
ATOM 428  C CA  . ARG A 1 151 ? 112.362 183.513 157.364 1.00 27.97 ? 151 ARG A CA  1 
ATOM 429  C C   . ARG A 1 151 ? 111.046 184.062 156.829 1.00 21.74 ? 151 ARG A C   1 
ATOM 430  O O   . ARG A 1 151 ? 110.666 183.781 155.688 1.00 20.50 ? 151 ARG A O   1 
ATOM 431  C CB  . ARG A 1 151 ? 113.536 184.275 156.747 1.00 22.91 ? 151 ARG A CB  1 
ATOM 432  C CG  . ARG A 1 151 ? 114.854 184.081 157.474 1.00 23.72 ? 151 ARG A CG  1 
ATOM 433  C CD  . ARG A 1 151 ? 115.924 185.008 156.925 1.00 24.37 ? 151 ARG A CD  1 
ATOM 434  N NE  . ARG A 1 151 ? 117.114 185.029 157.766 1.00 26.76 ? 151 ARG A NE  1 
ATOM 435  C CZ  . ARG A 1 151 ? 118.166 185.807 157.554 1.00 28.52 ? 151 ARG A CZ  1 
ATOM 436  N NH1 . ARG A 1 151 ? 118.212 186.645 156.531 1.00 25.66 ? 151 ARG A NH1 1 
ATOM 437  N NH2 . ARG A 1 151 ? 119.199 185.744 158.390 1.00 30.43 ? 151 ARG A NH2 1 
ATOM 438  N N   . TYR A 1 152 ? 110.356 184.842 157.661 1.00 25.76 ? 152 TYR A N   1 
ATOM 439  C CA  . TYR A 1 152 ? 109.134 185.551 157.282 1.00 21.78 ? 152 TYR A CA  1 
ATOM 440  C C   . TYR A 1 152 ? 109.318 186.996 157.740 1.00 23.68 ? 152 TYR A C   1 
ATOM 441  O O   . TYR A 1 152 ? 108.989 187.346 158.876 1.00 26.45 ? 152 TYR A O   1 
ATOM 442  C CB  . TYR A 1 152 ? 107.896 184.898 157.899 1.00 17.43 ? 152 TYR A CB  1 
ATOM 443  C CG  . TYR A 1 152 ? 106.581 185.586 157.582 1.00 23.10 ? 152 TYR A CG  1 
ATOM 444  C CD1 . TYR A 1 152 ? 106.469 186.478 156.522 1.00 24.33 ? 152 TYR A CD1 1 
ATOM 445  C CD2 . TYR A 1 152 ? 105.447 185.333 158.342 1.00 27.63 ? 152 TYR A CD2 1 
ATOM 446  C CE1 . TYR A 1 152 ? 105.271 187.105 156.238 1.00 25.11 ? 152 TYR A CE1 1 
ATOM 447  C CE2 . TYR A 1 152 ? 104.244 185.953 158.063 1.00 23.82 ? 152 TYR A CE2 1 
ATOM 448  C CZ  . TYR A 1 152 ? 104.161 186.837 157.010 1.00 24.64 ? 152 TYR A CZ  1 
ATOM 449  O OH  . TYR A 1 152 ? 102.965 187.456 156.728 1.00 29.62 ? 152 TYR A OH  1 
ATOM 450  N N   . TYR A 1 153 ? 109.845 187.830 156.848 1.00 30.47 ? 153 TYR A N   1 
ATOM 451  C CA  . TYR A 1 153 ? 110.108 189.233 157.136 1.00 26.34 ? 153 TYR A CA  1 
ATOM 452  C C   . TYR A 1 153 ? 108.996 190.075 156.523 1.00 24.83 ? 153 TYR A C   1 
ATOM 453  O O   . TYR A 1 153 ? 108.732 189.978 155.320 1.00 30.00 ? 153 TYR A O   1 
ATOM 454  C CB  . TYR A 1 153 ? 111.469 189.660 156.584 1.00 22.54 ? 153 TYR A CB  1 
ATOM 455  C CG  . TYR A 1 153 ? 112.662 189.166 157.377 1.00 22.15 ? 153 TYR A CG  1 
ATOM 456  C CD1 . TYR A 1 153 ? 112.533 188.150 158.315 1.00 25.79 ? 153 TYR A CD1 1 
ATOM 457  C CD2 . TYR A 1 153 ? 113.920 189.717 157.181 1.00 21.51 ? 153 TYR A CD2 1 
ATOM 458  C CE1 . TYR A 1 153 ? 113.622 187.699 159.035 1.00 26.52 ? 153 TYR A CE1 1 
ATOM 459  C CE2 . TYR A 1 153 ? 115.015 189.273 157.896 1.00 22.34 ? 153 TYR A CE2 1 
ATOM 460  C CZ  . TYR A 1 153 ? 114.861 188.265 158.821 1.00 24.14 ? 153 TYR A CZ  1 
ATOM 461  O OH  . TYR A 1 153 ? 115.950 187.821 159.535 1.00 30.74 ? 153 TYR A OH  1 
ATOM 462  N N   . ARG A 1 154 ? 108.349 190.897 157.347 1.00 33.17 ? 154 ARG A N   1 
ATOM 463  C CA  . ARG A 1 154 ? 107.239 191.728 156.895 1.00 29.35 ? 154 ARG A CA  1 
ATOM 464  C C   . ARG A 1 154 ? 107.405 193.132 157.452 1.00 32.92 ? 154 ARG A C   1 
ATOM 465  O O   . ARG A 1 154 ? 107.465 193.313 158.672 1.00 30.84 ? 154 ARG A O   1 
ATOM 466  C CB  . ARG A 1 154 ? 105.893 191.138 157.327 1.00 26.79 ? 154 ARG A CB  1 
ATOM 467  C CG  . ARG A 1 154 ? 104.691 191.941 156.862 1.00 35.23 ? 154 ARG A CG  1 
ATOM 468  C CD  . ARG A 1 154 ? 103.392 191.320 157.344 1.00 38.18 ? 154 ARG A CD  1 
ATOM 469  N NE  . ARG A 1 154 ? 102.226 192.033 156.837 1.00 41.54 ? 154 ARG A NE  1 
ATOM 470  C CZ  . ARG A 1 154 ? 100.971 191.676 157.070 1.00 43.21 ? 154 ARG A CZ  1 
ATOM 471  N NH1 . ARG A 1 154 ? 100.679 190.614 157.803 1.00 41.26 ? 154 ARG A NH1 1 
ATOM 472  N NH2 . ARG A 1 154 ? 99.983  192.403 156.555 1.00 38.29 ? 154 ARG A NH2 1 
ATOM 473  N N   . GLU A 1 155 ? 107.475 194.118 156.555 1.00 40.15 ? 155 GLU A N   1 
ATOM 474  C CA  . GLU A 1 155 ? 107.525 195.535 156.923 1.00 35.54 ? 155 GLU A CA  1 
ATOM 475  C C   . GLU A 1 155 ? 108.697 195.839 157.854 1.00 34.27 ? 155 GLU A C   1 
ATOM 476  O O   . GLU A 1 155 ? 108.584 196.644 158.780 1.00 37.52 ? 155 GLU A O   1 
ATOM 477  C CB  . GLU A 1 155 ? 106.204 195.987 157.549 1.00 35.18 ? 155 GLU A CB  1 
ATOM 478  C CG  . GLU A 1 155 ? 105.030 195.991 156.584 1.00 37.54 ? 155 GLU A CG  1 
ATOM 479  C CD  . GLU A 1 155 ? 103.694 196.102 157.291 1.00 43.67 ? 155 GLU A CD  1 
ATOM 480  O OE1 . GLU A 1 155 ? 103.488 195.382 158.291 1.00 43.82 ? 155 GLU A OE1 1 
ATOM 481  O OE2 . GLU A 1 155 ? 102.851 196.909 156.849 1.00 40.89 ? 155 GLU A OE2 1 
ATOM 482  N N   . ASN A 1 156 ? 109.834 195.201 157.601 1.00 28.51 ? 156 ASN A N   1 
ATOM 483  C CA  . ASN A 1 156 ? 111.037 195.403 158.398 1.00 29.54 ? 156 ASN A CA  1 
ATOM 484  C C   . ASN A 1 156 ? 111.943 196.410 157.703 1.00 30.86 ? 156 ASN A C   1 
ATOM 485  O O   . ASN A 1 156 ? 112.244 196.266 156.514 1.00 40.39 ? 156 ASN A O   1 
ATOM 486  C CB  . ASN A 1 156 ? 111.777 194.084 158.615 1.00 31.36 ? 156 ASN A CB  1 
ATOM 487  C CG  . ASN A 1 156 ? 110.896 193.019 159.233 1.00 30.47 ? 156 ASN A CG  1 
ATOM 488  O OD1 . ASN A 1 156 ? 110.296 192.208 158.528 1.00 38.20 ? 156 ASN A OD1 1 
ATOM 489  N ND2 . ASN A 1 156 ? 110.809 193.018 160.557 1.00 35.25 ? 156 ASN A ND2 1 
ATOM 490  N N   . MET A 1 157 ? 112.372 197.426 158.447 1.00 36.16 ? 157 MET A N   1 
ATOM 491  C CA  . MET A 1 157 ? 113.228 198.487 157.920 1.00 38.76 ? 157 MET A CA  1 
ATOM 492  C C   . MET A 1 157 ? 114.667 198.179 158.317 1.00 37.37 ? 157 MET A C   1 
ATOM 493  O O   . MET A 1 157 ? 115.062 198.378 159.469 1.00 41.20 ? 157 MET A O   1 
ATOM 494  C CB  . MET A 1 157 ? 112.782 199.850 158.438 1.00 36.94 ? 157 MET A CB  1 
ATOM 495  C CG  . MET A 1 157 ? 112.917 200.974 157.423 1.00 39.70 ? 157 MET A CG  1 
ATOM 496  S SD  . MET A 1 157 ? 114.634 201.411 157.087 1.00 53.93 ? 157 MET A SD  1 
ATOM 497  C CE  . MET A 1 157 ? 114.927 202.636 158.359 1.00 40.79 ? 157 MET A CE  1 
ATOM 498  N N   . TYR A 1 158 ? 115.450 197.693 157.359 1.00 32.10 ? 158 TYR A N   1 
ATOM 499  C CA  . TYR A 1 158 ? 116.860 197.380 157.571 1.00 23.33 ? 158 TYR A CA  1 
ATOM 500  C C   . TYR A 1 158 ? 117.687 198.519 156.987 1.00 30.62 ? 158 TYR A C   1 
ATOM 501  O O   . TYR A 1 158 ? 117.837 198.631 155.768 1.00 40.92 ? 158 TYR A O   1 
ATOM 502  C CB  . TYR A 1 158 ? 117.220 196.043 156.933 1.00 31.67 ? 158 TYR A CB  1 
ATOM 503  C CG  . TYR A 1 158 ? 116.885 194.846 157.792 1.00 28.88 ? 158 TYR A CG  1 
ATOM 504  C CD1 . TYR A 1 158 ? 117.808 194.335 158.694 1.00 26.36 ? 158 TYR A CD1 1 
ATOM 505  C CD2 . TYR A 1 158 ? 115.646 194.227 157.700 1.00 24.65 ? 158 TYR A CD2 1 
ATOM 506  C CE1 . TYR A 1 158 ? 117.506 193.242 159.481 1.00 28.95 ? 158 TYR A CE1 1 
ATOM 507  C CE2 . TYR A 1 158 ? 115.335 193.133 158.483 1.00 26.22 ? 158 TYR A CE2 1 
ATOM 508  C CZ  . TYR A 1 158 ? 116.269 192.645 159.371 1.00 31.59 ? 158 TYR A CZ  1 
ATOM 509  O OH  . TYR A 1 158 ? 115.966 191.556 160.153 1.00 31.35 ? 158 TYR A OH  1 
ATOM 510  N N   . ARG A 1 159 ? 118.226 199.365 157.861 1.00 31.91 ? 159 ARG A N   1 
ATOM 511  C CA  . ARG A 1 159 ? 119.034 200.509 157.454 1.00 31.02 ? 159 ARG A CA  1 
ATOM 512  C C   . ARG A 1 159 ? 120.505 200.157 157.642 1.00 34.81 ? 159 ARG A C   1 
ATOM 513  O O   . ARG A 1 159 ? 120.987 200.066 158.775 1.00 38.90 ? 159 ARG A O   1 
ATOM 514  C CB  . ARG A 1 159 ? 118.657 201.753 158.255 1.00 34.09 ? 159 ARG A CB  1 
ATOM 515  C CG  . ARG A 1 159 ? 119.073 203.057 157.596 1.00 35.39 ? 159 ARG A CG  1 
ATOM 516  C CD  . ARG A 1 159 ? 118.464 204.254 158.304 1.00 31.48 ? 159 ARG A CD  1 
ATOM 517  N NE  . ARG A 1 159 ? 118.543 205.462 157.492 1.00 35.04 ? 159 ARG A NE  1 
ATOM 518  C CZ  . ARG A 1 159 ? 117.654 205.805 156.570 1.00 39.92 ? 159 ARG A CZ  1 
ATOM 519  N NH1 . ARG A 1 159 ? 116.596 205.052 156.316 1.00 39.44 ? 159 ARG A NH1 1 
ATOM 520  N NH2 . ARG A 1 159 ? 117.829 206.932 155.886 1.00 35.94 ? 159 ARG A NH2 1 
ATOM 521  N N   . TYR A 1 160 ? 121.209 199.969 156.530 1.00 20.38 ? 160 TYR A N   1 
ATOM 522  C CA  . TYR A 1 160 ? 122.625 199.619 156.525 1.00 21.14 ? 160 TYR A CA  1 
ATOM 523  C C   . TYR A 1 160 ? 122.949 198.401 157.396 1.00 24.15 ? 160 TYR A C   1 
ATOM 524  O O   . TYR A 1 160 ? 123.751 198.496 158.331 1.00 29.58 ? 160 TYR A O   1 
ATOM 525  C CB  . TYR A 1 160 ? 123.467 200.815 156.948 1.00 25.04 ? 160 TYR A CB  1 
ATOM 526  C CG  . TYR A 1 160 ? 123.513 201.939 155.937 1.00 28.24 ? 160 TYR A CG  1 
ATOM 527  C CD1 . TYR A 1 160 ? 122.444 202.814 155.792 1.00 28.18 ? 160 TYR A CD1 1 
ATOM 528  C CD2 . TYR A 1 160 ? 124.629 202.131 155.134 1.00 30.07 ? 160 TYR A CD2 1 
ATOM 529  C CE1 . TYR A 1 160 ? 122.484 203.844 154.871 1.00 26.68 ? 160 TYR A CE1 1 
ATOM 530  C CE2 . TYR A 1 160 ? 124.678 203.158 154.211 1.00 26.95 ? 160 TYR A CE2 1 
ATOM 531  C CZ  . TYR A 1 160 ? 123.603 204.011 154.083 1.00 25.00 ? 160 TYR A CZ  1 
ATOM 532  O OH  . TYR A 1 160 ? 123.647 205.035 153.166 1.00 31.55 ? 160 TYR A OH  1 
ATOM 533  N N   . PRO A 1 161 ? 122.348 197.242 157.119 1.00 20.42 ? 161 PRO A N   1 
ATOM 534  C CA  . PRO A 1 161 ? 122.714 196.037 157.871 1.00 18.89 ? 161 PRO A CA  1 
ATOM 535  C C   . PRO A 1 161 ? 124.016 195.430 157.374 1.00 21.09 ? 161 PRO A C   1 
ATOM 536  O O   . PRO A 1 161 ? 124.295 195.402 156.173 1.00 24.28 ? 161 PRO A O   1 
ATOM 537  C CB  . PRO A 1 161 ? 121.526 195.098 157.631 1.00 13.88 ? 161 PRO A CB  1 
ATOM 538  C CG  . PRO A 1 161 ? 121.014 195.489 156.306 1.00 20.22 ? 161 PRO A CG  1 
ATOM 539  C CD  . PRO A 1 161 ? 121.292 196.963 156.128 1.00 19.05 ? 161 PRO A CD  1 
ATOM 540  N N   . ASN A 1 162 ? 124.812 194.939 158.326 1.00 20.79 ? 162 ASN A N   1 
ATOM 541  C CA  . ASN A 1 162 ? 126.123 194.351 158.044 1.00 15.77 ? 162 ASN A CA  1 
ATOM 542  C C   . ASN A 1 162 ? 127.008 195.324 157.270 1.00 15.47 ? 162 ASN A C   1 
ATOM 543  O O   . ASN A 1 162 ? 127.722 194.947 156.338 1.00 27.93 ? 162 ASN A O   1 
ATOM 544  C CB  . ASN A 1 162 ? 125.983 193.023 157.298 1.00 19.21 ? 162 ASN A CB  1 
ATOM 545  C CG  . ASN A 1 162 ? 125.067 192.048 158.011 1.00 23.01 ? 162 ASN A CG  1 
ATOM 546  O OD1 . ASN A 1 162 ? 125.285 191.710 159.173 1.00 23.24 ? 162 ASN A OD1 1 
ATOM 547  N ND2 . ASN A 1 162 ? 124.034 191.589 157.314 1.00 28.10 ? 162 ASN A ND2 1 
ATOM 548  N N   . GLN A 1 163 ? 126.959 196.594 157.663 1.00 19.47 ? 163 GLN A N   1 
ATOM 549  C CA  . GLN A 1 163 ? 127.735 197.629 156.997 1.00 23.52 ? 163 GLN A CA  1 
ATOM 550  C C   . GLN A 1 163 ? 129.174 197.613 157.496 1.00 28.33 ? 163 GLN A C   1 
ATOM 551  O O   . GLN A 1 163 ? 129.422 197.544 158.704 1.00 32.85 ? 163 GLN A O   1 
ATOM 552  C CB  . GLN A 1 163 ? 127.105 199.001 157.235 1.00 17.53 ? 163 GLN A CB  1 
ATOM 553  C CG  . GLN A 1 163 ? 127.398 200.017 156.145 1.00 25.39 ? 163 GLN A CG  1 
ATOM 554  C CD  . GLN A 1 163 ? 128.478 201.003 156.541 1.00 28.85 ? 163 GLN A CD  1 
ATOM 555  O OE1 . GLN A 1 163 ? 129.114 200.857 157.585 1.00 29.13 ? 163 GLN A OE1 1 
ATOM 556  N NE2 . GLN A 1 163 ? 128.690 202.013 155.709 1.00 31.23 ? 163 GLN A NE2 1 
ATOM 557  N N   . VAL A 1 164 ? 130.119 197.675 156.565 1.00 28.26 ? 164 VAL A N   1 
ATOM 558  C CA  . VAL A 1 164 ? 131.542 197.705 156.879 1.00 21.81 ? 164 VAL A CA  1 
ATOM 559  C C   . VAL A 1 164 ? 132.049 199.094 156.516 1.00 29.00 ? 164 VAL A C   1 
ATOM 560  O O   . VAL A 1 164 ? 132.384 199.363 155.357 1.00 32.82 ? 164 VAL A O   1 
ATOM 561  C CB  . VAL A 1 164 ? 132.320 196.614 156.136 1.00 31.55 ? 164 VAL A CB  1 
ATOM 562  C CG1 . VAL A 1 164 ? 133.765 196.586 156.607 1.00 23.51 ? 164 VAL A CG1 1 
ATOM 563  C CG2 . VAL A 1 164 ? 131.662 195.260 156.338 1.00 30.10 ? 164 VAL A CG2 1 
ATOM 564  N N   . TYR A 1 165 ? 132.111 199.985 157.506 1.00 34.19 ? 165 TYR A N   1 
ATOM 565  C CA  . TYR A 1 165 ? 132.640 201.332 157.300 1.00 28.28 ? 165 TYR A CA  1 
ATOM 566  C C   . TYR A 1 165 ? 134.151 201.281 157.504 1.00 33.76 ? 165 TYR A C   1 
ATOM 567  O O   . TYR A 1 165 ? 134.685 201.597 158.569 1.00 40.58 ? 165 TYR A O   1 
ATOM 568  C CB  . TYR A 1 165 ? 131.968 202.327 158.238 1.00 29.51 ? 165 TYR A CB  1 
ATOM 569  C CG  . TYR A 1 165 ? 131.900 203.730 157.683 1.00 33.82 ? 165 TYR A CG  1 
ATOM 570  C CD1 . TYR A 1 165 ? 130.859 204.118 156.850 1.00 33.51 ? 165 TYR A CD1 1 
ATOM 571  C CD2 . TYR A 1 165 ? 132.879 204.666 157.987 1.00 33.01 ? 165 TYR A CD2 1 
ATOM 572  C CE1 . TYR A 1 165 ? 130.794 205.400 156.338 1.00 32.79 ? 165 TYR A CE1 1 
ATOM 573  C CE2 . TYR A 1 165 ? 132.823 205.950 157.479 1.00 29.38 ? 165 TYR A CE2 1 
ATOM 574  C CZ  . TYR A 1 165 ? 131.778 206.311 156.655 1.00 29.63 ? 165 TYR A CZ  1 
ATOM 575  O OH  . TYR A 1 165 ? 131.717 207.589 156.148 1.00 33.49 ? 165 TYR A OH  1 
ATOM 576  N N   . TYR A 1 166 ? 134.848 200.868 156.447 1.00 32.05 ? 166 TYR A N   1 
ATOM 577  C CA  . TYR A 1 166 ? 136.298 200.686 156.483 1.00 29.32 ? 166 TYR A CA  1 
ATOM 578  C C   . TYR A 1 166 ? 136.947 201.994 156.052 1.00 34.30 ? 166 TYR A C   1 
ATOM 579  O O   . TYR A 1 166 ? 137.150 202.252 154.865 1.00 41.73 ? 166 TYR A O   1 
ATOM 580  C CB  . TYR A 1 166 ? 136.712 199.526 155.586 1.00 26.97 ? 166 TYR A CB  1 
ATOM 581  C CG  . TYR A 1 166 ? 138.153 199.098 155.745 1.00 34.77 ? 166 TYR A CG  1 
ATOM 582  C CD1 . TYR A 1 166 ? 138.525 198.203 156.738 1.00 32.51 ? 166 TYR A CD1 1 
ATOM 583  C CD2 . TYR A 1 166 ? 139.142 199.591 154.905 1.00 32.02 ? 166 TYR A CD2 1 
ATOM 584  C CE1 . TYR A 1 166 ? 139.840 197.807 156.887 1.00 34.92 ? 166 TYR A CE1 1 
ATOM 585  C CE2 . TYR A 1 166 ? 140.460 199.203 155.048 1.00 31.55 ? 166 TYR A CE2 1 
ATOM 586  C CZ  . TYR A 1 166 ? 140.803 198.311 156.041 1.00 35.62 ? 166 TYR A CZ  1 
ATOM 587  O OH  . TYR A 1 166 ? 142.114 197.921 156.188 1.00 38.33 ? 166 TYR A OH  1 
ATOM 588  N N   . ARG A 1 167 ? 137.279 202.834 157.031 1.00 33.37 ? 167 ARG A N   1 
ATOM 589  C CA  . ARG A 1 167 ? 137.873 204.149 156.785 1.00 38.24 ? 167 ARG A CA  1 
ATOM 590  C C   . ARG A 1 167 ? 139.099 204.340 157.672 1.00 40.68 ? 167 ARG A C   1 
ATOM 591  O O   . ARG A 1 167 ? 139.076 205.129 158.625 1.00 37.52 ? 167 ARG A O   1 
ATOM 592  C CB  . ARG A 1 167 ? 136.844 205.255 157.026 1.00 30.11 ? 167 ARG A CB  1 
ATOM 593  C CG  . ARG A 1 167 ? 137.271 206.643 156.567 1.00 30.04 ? 167 ARG A CG  1 
ATOM 594  C CD  . ARG A 1 167 ? 136.671 206.991 155.222 1.00 39.27 ? 167 ARG A CD  1 
ATOM 595  N NE  . ARG A 1 167 ? 136.974 208.361 154.823 1.00 36.94 ? 167 ARG A NE  1 
ATOM 596  C CZ  . ARG A 1 167 ? 136.098 209.356 154.839 1.00 38.27 ? 167 ARG A CZ  1 
ATOM 597  N NH1 . ARG A 1 167 ? 134.847 209.169 155.227 1.00 41.74 ? 167 ARG A NH1 1 
ATOM 598  N NH2 . ARG A 1 167 ? 136.486 210.568 154.455 1.00 39.05 ? 167 ARG A NH2 1 
ATOM 599  N N   . PRO A 1 168 ? 140.191 203.628 157.392 1.00 38.42 ? 168 PRO A N   1 
ATOM 600  C CA  . PRO A 1 168 ? 141.427 203.860 158.148 1.00 30.85 ? 168 PRO A CA  1 
ATOM 601  C C   . PRO A 1 168 ? 142.148 205.114 157.681 1.00 33.12 ? 168 PRO A C   1 
ATOM 602  O O   . PRO A 1 168 ? 142.182 205.432 156.490 1.00 38.90 ? 168 PRO A O   1 
ATOM 603  C CB  . PRO A 1 168 ? 142.257 202.603 157.863 1.00 30.80 ? 168 PRO A CB  1 
ATOM 604  C CG  . PRO A 1 168 ? 141.787 202.145 156.544 1.00 31.95 ? 168 PRO A CG  1 
ATOM 605  C CD  . PRO A 1 168 ? 140.326 202.494 156.461 1.00 31.88 ? 168 PRO A CD  1 
ATOM 606  N N   . VAL A 1 169 ? 142.726 205.832 158.642 1.00 37.48 ? 169 VAL A N   1 
ATOM 607  C CA  . VAL A 1 169 ? 143.495 207.041 158.377 1.00 38.75 ? 169 VAL A CA  1 
ATOM 608  C C   . VAL A 1 169 ? 144.851 206.908 159.056 1.00 42.93 ? 169 VAL A C   1 
ATOM 609  O O   . VAL A 1 169 ? 144.919 206.640 160.261 1.00 42.92 ? 169 VAL A O   1 
ATOM 610  C CB  . VAL A 1 169 ? 142.768 208.307 158.869 1.00 30.52 ? 169 VAL A CB  1 
ATOM 611  C CG1 . VAL A 1 169 ? 143.583 209.547 158.539 1.00 34.99 ? 169 VAL A CG1 1 
ATOM 612  C CG2 . VAL A 1 169 ? 141.378 208.398 158.257 1.00 31.16 ? 169 VAL A CG2 1 
ATOM 613  N N   . ASP A 1 170 ? 145.922 207.098 158.285 1.00 34.93 ? 170 ASP A N   1 
ATOM 614  C CA  . ASP A 1 170 ? 147.292 207.087 158.800 1.00 29.56 ? 170 ASP A CA  1 
ATOM 615  C C   . ASP A 1 170 ? 147.591 205.798 159.564 1.00 30.61 ? 170 ASP A C   1 
ATOM 616  O O   . ASP A 1 170 ? 148.142 205.809 160.667 1.00 34.97 ? 170 ASP A O   1 
ATOM 617  C CB  . ASP A 1 170 ? 147.555 208.313 159.675 1.00 34.32 ? 170 ASP A CB  1 
ATOM 618  C CG  . ASP A 1 170 ? 147.296 209.616 158.947 1.00 38.06 ? 170 ASP A CG  1 
ATOM 619  O OD1 . ASP A 1 170 ? 146.952 209.572 157.748 1.00 42.49 ? 170 ASP A OD1 1 
ATOM 620  O OD2 . ASP A 1 170 ? 147.437 210.687 159.574 1.00 39.16 ? 170 ASP A OD2 1 
ATOM 621  N N   . GLN A 1 171 ? 147.219 204.671 158.963 1.00 33.72 ? 171 GLN A N   1 
ATOM 622  C CA  . GLN A 1 171 ? 147.443 203.364 159.573 1.00 34.83 ? 171 GLN A CA  1 
ATOM 623  C C   . GLN A 1 171 ? 148.868 202.921 159.263 1.00 33.08 ? 171 GLN A C   1 
ATOM 624  O O   . GLN A 1 171 ? 149.199 202.637 158.108 1.00 30.74 ? 171 GLN A O   1 
ATOM 625  C CB  . GLN A 1 171 ? 146.419 202.356 159.058 1.00 25.75 ? 171 GLN A CB  1 
ATOM 626  C CG  . GLN A 1 171 ? 146.046 201.278 160.060 1.00 28.18 ? 171 GLN A CG  1 
ATOM 627  C CD  . GLN A 1 171 ? 144.989 200.329 159.527 1.00 28.61 ? 171 GLN A CD  1 
ATOM 628  O OE1 . GLN A 1 171 ? 144.836 200.171 158.316 1.00 34.46 ? 171 GLN A OE1 1 
ATOM 629  N NE2 . GLN A 1 171 ? 144.254 199.692 160.430 1.00 23.06 ? 171 GLN A NE2 1 
ATOM 630  N N   . TYR A 1 172 ? 149.714 202.863 160.290 1.00 33.45 ? 172 TYR A N   1 
ATOM 631  C CA  . TYR A 1 172 ? 151.109 202.441 160.161 1.00 29.28 ? 172 TYR A CA  1 
ATOM 632  C C   . TYR A 1 172 ? 151.310 201.225 161.058 1.00 35.69 ? 172 TYR A C   1 
ATOM 633  O O   . TYR A 1 172 ? 151.781 201.344 162.190 1.00 42.15 ? 172 TYR A O   1 
ATOM 634  C CB  . TYR A 1 172 ? 152.077 203.580 160.533 1.00 34.16 ? 172 TYR A CB  1 
ATOM 635  C CG  . TYR A 1 172 ? 152.099 204.742 159.565 1.00 33.89 ? 172 TYR A CG  1 
ATOM 636  C CD1 . TYR A 1 172 ? 151.066 205.669 159.537 1.00 29.80 ? 172 TYR A CD1 1 
ATOM 637  C CD2 . TYR A 1 172 ? 153.164 204.923 158.693 1.00 35.67 ? 172 TYR A CD2 1 
ATOM 638  C CE1 . TYR A 1 172 ? 151.086 206.735 158.658 1.00 32.75 ? 172 TYR A CE1 1 
ATOM 639  C CE2 . TYR A 1 172 ? 153.194 205.987 157.812 1.00 37.83 ? 172 TYR A CE2 1 
ATOM 640  C CZ  . TYR A 1 172 ? 152.152 206.889 157.798 1.00 40.65 ? 172 TYR A CZ  1 
ATOM 641  O OH  . TYR A 1 172 ? 152.177 207.950 156.922 1.00 44.24 ? 172 TYR A OH  1 
ATOM 642  N N   . ASN A 1 173 ? 150.982 200.046 160.540 1.00 27.02 ? 173 ASN A N   1 
ATOM 643  C CA  . ASN A 1 173 ? 151.053 198.812 161.311 1.00 23.51 ? 173 ASN A CA  1 
ATOM 644  C C   . ASN A 1 173 ? 152.068 197.867 160.685 1.00 31.96 ? 173 ASN A C   1 
ATOM 645  O O   . ASN A 1 173 ? 152.207 197.811 159.459 1.00 35.72 ? 173 ASN A O   1 
ATOM 646  C CB  . ASN A 1 173 ? 149.686 198.131 161.397 1.00 22.96 ? 173 ASN A CB  1 
ATOM 647  C CG  . ASN A 1 173 ? 148.690 198.926 162.215 1.00 32.44 ? 173 ASN A CG  1 
ATOM 648  O OD1 . ASN A 1 173 ? 149.068 199.718 163.077 1.00 38.15 ? 173 ASN A OD1 1 
ATOM 649  N ND2 . ASN A 1 173 ? 147.406 198.717 161.948 1.00 32.79 ? 173 ASN A ND2 1 
ATOM 650  N N   . ASN A 1 174 ? 152.774 197.125 161.536 1.00 30.72 ? 174 ASN A N   1 
ATOM 651  C CA  . ASN A 1 174 ? 153.814 196.200 161.101 1.00 20.94 ? 174 ASN A CA  1 
ATOM 652  C C   . ASN A 1 174 ? 153.584 194.848 161.756 1.00 25.58 ? 174 ASN A C   1 
ATOM 653  O O   . ASN A 1 174 ? 153.635 194.734 162.985 1.00 36.65 ? 174 ASN A O   1 
ATOM 654  C CB  . ASN A 1 174 ? 155.206 196.733 161.451 1.00 19.07 ? 174 ASN A CB  1 
ATOM 655  C CG  . ASN A 1 174 ? 155.618 197.901 160.581 1.00 30.17 ? 174 ASN A CG  1 
ATOM 656  O OD1 . ASN A 1 174 ? 155.228 199.042 160.829 1.00 38.76 ? 174 ASN A OD1 1 
ATOM 657  N ND2 . ASN A 1 174 ? 156.415 197.624 159.555 1.00 26.67 ? 174 ASN A ND2 1 
ATOM 658  N N   . GLN A 1 175 ? 153.331 193.828 160.936 1.00 29.57 ? 175 GLN A N   1 
ATOM 659  C CA  . GLN A 1 175 ? 153.240 192.438 161.385 1.00 30.86 ? 175 GLN A CA  1 
ATOM 660  C C   . GLN A 1 175 ? 154.152 191.631 160.466 1.00 29.89 ? 175 GLN A C   1 
ATOM 661  O O   . GLN A 1 175 ? 153.700 191.058 159.472 1.00 29.59 ? 175 GLN A O   1 
ATOM 662  C CB  . GLN A 1 175 ? 151.802 191.931 161.354 1.00 22.86 ? 175 GLN A CB  1 
ATOM 663  C CG  . GLN A 1 175 ? 151.603 190.590 162.039 1.00 24.78 ? 175 GLN A CG  1 
ATOM 664  C CD  . GLN A 1 175 ? 150.140 190.229 162.201 1.00 26.54 ? 175 GLN A CD  1 
ATOM 665  O OE1 . GLN A 1 175 ? 149.299 190.623 161.394 1.00 33.43 ? 175 GLN A OE1 1 
ATOM 666  N NE2 . GLN A 1 175 ? 149.830 189.477 163.249 1.00 27.21 ? 175 GLN A NE2 1 
ATOM 667  N N   . ASN A 1 176 ? 155.437 191.582 160.806 1.00 26.95 ? 176 ASN A N   1 
ATOM 668  C CA  . ASN A 1 176 ? 156.451 190.998 159.944 1.00 26.18 ? 176 ASN A CA  1 
ATOM 669  C C   . ASN A 1 176 ? 157.139 189.834 160.643 1.00 30.01 ? 176 ASN A C   1 
ATOM 670  O O   . ASN A 1 176 ? 157.321 189.838 161.863 1.00 30.20 ? 176 ASN A O   1 
ATOM 671  C CB  . ASN A 1 176 ? 157.496 192.043 159.534 1.00 32.05 ? 176 ASN A CB  1 
ATOM 672  C CG  . ASN A 1 176 ? 156.874 193.272 158.904 1.00 34.20 ? 176 ASN A CG  1 
ATOM 673  O OD1 . ASN A 1 176 ? 155.921 193.172 158.132 1.00 35.76 ? 176 ASN A OD1 1 
ATOM 674  N ND2 . ASN A 1 176 ? 157.410 194.441 159.233 1.00 35.64 ? 176 ASN A ND2 1 
ATOM 675  N N   . THR A 1 177 ? 157.523 188.838 159.851 1.00 40.26 ? 177 THR A N   1 
ATOM 676  C CA  . THR A 1 177 ? 158.272 187.685 160.331 1.00 36.19 ? 177 THR A CA  1 
ATOM 677  C C   . THR A 1 177 ? 159.707 187.800 159.836 1.00 30.76 ? 177 THR A C   1 
ATOM 678  O O   . THR A 1 177 ? 159.946 187.865 158.625 1.00 36.74 ? 177 THR A O   1 
ATOM 679  C CB  . THR A 1 177 ? 157.642 186.378 159.850 1.00 32.36 ? 177 THR A CB  1 
ATOM 680  O OG1 . THR A 1 177 ? 156.313 186.264 160.373 1.00 28.76 ? 177 THR A OG1 1 
ATOM 681  C CG2 . THR A 1 177 ? 158.470 185.192 160.313 1.00 33.83 ? 177 THR A CG2 1 
ATOM 682  N N   . PHE A 1 178 ? 160.654 187.827 160.769 1.00 28.92 ? 178 PHE A N   1 
ATOM 683  C CA  . PHE A 1 178 ? 162.071 187.950 160.451 1.00 29.69 ? 178 PHE A CA  1 
ATOM 684  C C   . PHE A 1 178 ? 162.788 186.690 160.908 1.00 34.55 ? 178 PHE A C   1 
ATOM 685  O O   . PHE A 1 178 ? 162.725 186.329 162.088 1.00 39.63 ? 178 PHE A O   1 
ATOM 686  C CB  . PHE A 1 178 ? 162.678 189.187 161.117 1.00 30.28 ? 178 PHE A CB  1 
ATOM 687  C CG  . PHE A 1 178 ? 162.540 190.442 160.305 1.00 33.96 ? 178 PHE A CG  1 
ATOM 688  C CD1 . PHE A 1 178 ? 161.401 191.224 160.404 1.00 33.69 ? 178 PHE A CD1 1 
ATOM 689  C CD2 . PHE A 1 178 ? 163.548 190.839 159.444 1.00 36.35 ? 178 PHE A CD2 1 
ATOM 690  C CE1 . PHE A 1 178 ? 161.271 192.379 159.657 1.00 35.22 ? 178 PHE A CE1 1 
ATOM 691  C CE2 . PHE A 1 178 ? 163.424 191.994 158.695 1.00 38.84 ? 178 PHE A CE2 1 
ATOM 692  C CZ  . PHE A 1 178 ? 162.283 192.765 158.802 1.00 39.11 ? 178 PHE A CZ  1 
ATOM 693  N N   . VAL A 1 179 ? 163.466 186.025 159.977 1.00 37.15 ? 179 VAL A N   1 
ATOM 694  C CA  . VAL A 1 179 ? 164.255 184.835 160.270 1.00 30.20 ? 179 VAL A CA  1 
ATOM 695  C C   . VAL A 1 179 ? 165.667 185.077 159.763 1.00 26.14 ? 179 VAL A C   1 
ATOM 696  O O   . VAL A 1 179 ? 165.880 185.225 158.554 1.00 34.27 ? 179 VAL A O   1 
ATOM 697  C CB  . VAL A 1 179 ? 163.658 183.570 159.631 1.00 29.16 ? 179 VAL A CB  1 
ATOM 698  C CG1 . VAL A 1 179 ? 164.643 182.415 159.721 1.00 29.18 ? 179 VAL A CG1 1 
ATOM 699  C CG2 . VAL A 1 179 ? 162.349 183.207 160.308 1.00 28.26 ? 179 VAL A CG2 1 
ATOM 700  N N   . HIS A 1 180 ? 166.628 185.119 160.682 1.00 30.99 ? 180 HIS A N   1 
ATOM 701  C CA  . HIS A 1 180 ? 168.036 185.305 160.351 1.00 35.83 ? 180 HIS A CA  1 
ATOM 702  C C   . HIS A 1 180 ? 168.797 184.078 160.832 1.00 34.92 ? 180 HIS A C   1 
ATOM 703  O O   . HIS A 1 180 ? 169.009 183.906 162.037 1.00 41.11 ? 180 HIS A O   1 
ATOM 704  C CB  . HIS A 1 180 ? 168.588 186.582 160.984 1.00 37.66 ? 180 HIS A CB  1 
ATOM 705  C CG  . HIS A 1 180 ? 168.317 187.817 160.184 1.00 37.42 ? 180 HIS A CG  1 
ATOM 706  N ND1 . HIS A 1 180 ? 169.203 188.871 160.119 1.00 35.05 ? 180 HIS A ND1 1 
ATOM 707  C CD2 . HIS A 1 180 ? 167.260 188.167 159.414 1.00 38.81 ? 180 HIS A CD2 1 
ATOM 708  C CE1 . HIS A 1 180 ? 168.703 189.817 159.344 1.00 41.71 ? 180 HIS A CE1 1 
ATOM 709  N NE2 . HIS A 1 180 ? 167.525 189.414 158.903 1.00 38.77 ? 180 HIS A NE2 1 
ATOM 710  N N   . ASP A 1 181 ? 169.203 183.228 159.893 1.00 45.73 ? 181 ASP A N   1 
ATOM 711  C CA  . ASP A 1 181 ? 169.917 181.996 160.199 1.00 45.25 ? 181 ASP A CA  1 
ATOM 712  C C   . ASP A 1 181 ? 171.285 182.043 159.537 1.00 44.49 ? 181 ASP A C   1 
ATOM 713  O O   . ASP A 1 181 ? 171.378 182.169 158.311 1.00 43.21 ? 181 ASP A O   1 
ATOM 714  C CB  . ASP A 1 181 ? 169.130 180.773 159.725 1.00 41.27 ? 181 ASP A CB  1 
ATOM 715  C CG  . ASP A 1 181 ? 169.681 179.475 160.279 1.00 47.44 ? 181 ASP A CG  1 
ATOM 716  O OD1 . ASP A 1 181 ? 169.545 179.243 161.498 1.00 50.55 ? 181 ASP A OD1 1 
ATOM 717  O OD2 . ASP A 1 181 ? 170.251 178.688 159.495 1.00 46.95 ? 181 ASP A OD2 1 
ATOM 718  N N   . CYS A 1 182 ? 172.337 181.936 160.349 1.00 41.99 ? 182 CYS A N   1 
ATOM 719  C CA  . CYS A 1 182 ? 173.717 181.899 159.863 1.00 37.09 ? 182 CYS A CA  1 
ATOM 720  C C   . CYS A 1 182 ? 174.048 183.126 159.017 1.00 39.66 ? 182 CYS A C   1 
ATOM 721  O O   . CYS A 1 182 ? 174.674 183.026 157.961 1.00 43.22 ? 182 CYS A O   1 
ATOM 722  C CB  . CYS A 1 182 ? 173.985 180.612 159.083 1.00 40.47 ? 182 CYS A CB  1 
ATOM 723  S SG  . CYS A 1 182 ? 174.002 179.132 160.110 1.00 63.20 ? 182 CYS A SG  1 
ATOM 724  N N   . VAL A 1 183 ? 173.627 184.294 159.487 1.00 36.16 ? 183 VAL A N   1 
ATOM 725  C CA  . VAL A 1 183 ? 173.867 185.552 158.793 1.00 33.28 ? 183 VAL A CA  1 
ATOM 726  C C   . VAL A 1 183 ? 175.056 186.248 159.436 1.00 24.08 ? 183 VAL A C   1 
ATOM 727  O O   . VAL A 1 183 ? 175.323 186.092 160.633 1.00 36.03 ? 183 VAL A O   1 
ATOM 728  C CB  . VAL A 1 183 ? 172.613 186.452 158.814 1.00 33.36 ? 183 VAL A CB  1 
ATOM 729  C CG1 . VAL A 1 183 ? 172.916 187.809 158.195 1.00 35.78 ? 183 VAL A CG1 1 
ATOM 730  C CG2 . VAL A 1 183 ? 171.465 185.775 158.086 1.00 30.11 ? 183 VAL A CG2 1 
ATOM 731  N N   . ASN A 1 184 ? 175.778 187.026 158.627 1.00 27.82 ? 184 ASN A N   1 
ATOM 732  C CA  . ASN A 1 184 ? 176.940 187.792 159.082 1.00 35.27 ? 184 ASN A CA  1 
ATOM 733  C C   . ASN A 1 184 ? 177.995 186.888 159.716 1.00 32.20 ? 184 ASN A C   1 
ATOM 734  O O   . ASN A 1 184 ? 178.586 187.219 160.746 1.00 29.28 ? 184 ASN A O   1 
ATOM 735  C CB  . ASN A 1 184 ? 176.525 188.905 160.048 1.00 33.08 ? 184 ASN A CB  1 
ATOM 736  C CG  . ASN A 1 184 ? 175.702 189.986 159.373 1.00 32.32 ? 184 ASN A CG  1 
ATOM 737  O OD1 . ASN A 1 184 ? 175.156 189.780 158.290 1.00 34.08 ? 184 ASN A OD1 1 
ATOM 738  N ND2 . ASN A 1 184 ? 175.611 191.146 160.012 1.00 34.73 ? 184 ASN A ND2 1 
ATOM 739  N N   . ILE A 1 185 ? 178.234 185.737 159.097 1.00 30.52 ? 185 ILE A N   1 
ATOM 740  C CA  . ILE A 1 185 ? 179.273 184.815 159.541 1.00 30.93 ? 185 ILE A CA  1 
ATOM 741  C C   . ILE A 1 185 ? 180.572 185.193 158.842 1.00 27.44 ? 185 ILE A C   1 
ATOM 742  O O   . ILE A 1 185 ? 180.637 185.222 157.608 1.00 31.09 ? 185 ILE A O   1 
ATOM 743  C CB  . ILE A 1 185 ? 178.890 183.358 159.246 1.00 30.18 ? 185 ILE A CB  1 
ATOM 744  C CG1 . ILE A 1 185 ? 177.676 182.947 160.080 1.00 30.01 ? 185 ILE A CG1 1 
ATOM 745  C CG2 . ILE A 1 185 ? 180.070 182.436 159.514 1.00 27.74 ? 185 ILE A CG2 1 
ATOM 746  C CD1 . ILE A 1 185 ? 177.400 181.460 160.066 1.00 30.44 ? 185 ILE A CD1 1 
ATOM 747  N N   . THR A 1 186 ? 181.606 185.481 159.627 1.00 27.62 ? 186 THR A N   1 
ATOM 748  C CA  . THR A 1 186 ? 182.875 185.956 159.093 1.00 33.30 ? 186 THR A CA  1 
ATOM 749  C C   . THR A 1 186 ? 184.018 185.124 159.655 1.00 30.62 ? 186 THR A C   1 
ATOM 750  O O   . THR A 1 186 ? 184.134 184.962 160.874 1.00 24.31 ? 186 THR A O   1 
ATOM 751  C CB  . THR A 1 186 ? 183.095 187.437 159.423 1.00 34.76 ? 186 THR A CB  1 
ATOM 752  O OG1 . THR A 1 186 ? 181.997 188.207 158.919 1.00 42.10 ? 186 THR A OG1 1 
ATOM 753  C CG2 . THR A 1 186 ? 184.388 187.937 158.796 1.00 33.05 ? 186 THR A CG2 1 
ATOM 754  N N   . VAL A 1 187 ? 184.855 184.602 158.763 1.00 28.27 ? 187 VAL A N   1 
ATOM 755  C CA  . VAL A 1 187 ? 186.107 183.946 159.123 1.00 27.56 ? 187 VAL A CA  1 
ATOM 756  C C   . VAL A 1 187 ? 187.198 184.702 158.378 1.00 26.51 ? 187 VAL A C   1 
ATOM 757  O O   . VAL A 1 187 ? 187.427 184.466 157.186 1.00 36.66 ? 187 VAL A O   1 
ATOM 758  C CB  . VAL A 1 187 ? 186.112 182.455 158.769 1.00 28.93 ? 187 VAL A CB  1 
ATOM 759  C CG1 . VAL A 1 187 ? 187.342 181.779 159.348 1.00 29.77 ? 187 VAL A CG1 1 
ATOM 760  C CG2 . VAL A 1 187 ? 184.843 181.783 159.273 1.00 30.31 ? 187 VAL A CG2 1 
ATOM 761  N N   . LYS A 1 188 ? 187.878 185.612 159.072 1.00 23.75 ? 188 LYS A N   1 
ATOM 762  C CA  . LYS A 1 188 ? 188.762 186.567 158.423 1.00 29.88 ? 188 LYS A CA  1 
ATOM 763  C C   . LYS A 1 188 ? 190.075 186.669 159.186 1.00 28.73 ? 188 LYS A C   1 
ATOM 764  O O   . LYS A 1 188 ? 190.130 186.433 160.394 1.00 41.12 ? 188 LYS A O   1 
ATOM 765  C CB  . LYS A 1 188 ? 188.099 187.951 158.326 1.00 29.75 ? 188 LYS A CB  1 
ATOM 766  C CG  . LYS A 1 188 ? 188.812 188.945 157.422 1.00 28.86 ? 188 LYS A CG  1 
ATOM 767  C CD  . LYS A 1 188 ? 188.186 190.326 157.522 1.00 27.86 ? 188 LYS A CD  1 
ATOM 768  C CE  . LYS A 1 188 ? 188.920 191.330 156.648 1.00 38.02 ? 188 LYS A CE  1 
ATOM 769  N NZ  . LYS A 1 188 ? 188.457 192.724 156.890 1.00 31.08 ? 188 LYS A NZ  1 
ATOM 770  N N   . GLN A 1 189 ? 191.136 187.012 158.459 1.00 38.59 ? 189 GLN A N   1 
ATOM 771  C CA  . GLN A 1 189 ? 192.423 187.370 159.048 1.00 40.40 ? 189 GLN A CA  1 
ATOM 772  C C   . GLN A 1 189 ? 192.839 188.710 158.459 1.00 42.87 ? 189 GLN A C   1 
ATOM 773  O O   . GLN A 1 189 ? 193.161 188.797 157.269 1.00 47.50 ? 189 GLN A O   1 
ATOM 774  C CB  . GLN A 1 189 ? 193.481 186.297 158.786 1.00 40.37 ? 189 GLN A CB  1 
ATOM 775  C CG  . GLN A 1 189 ? 193.345 185.587 157.451 1.00 44.91 ? 189 GLN A CG  1 
ATOM 776  C CD  . GLN A 1 189 ? 194.335 184.450 157.297 1.00 46.36 ? 189 GLN A CD  1 
ATOM 777  O OE1 . GLN A 1 189 ? 195.162 184.208 158.176 1.00 46.81 ? 189 GLN A OE1 1 
ATOM 778  N NE2 . GLN A 1 189 ? 194.258 183.744 156.174 1.00 41.98 ? 189 GLN A NE2 1 
ATOM 779  N N   . HIS A 1 190 ? 192.830 189.753 159.285 1.00 35.85 ? 190 HIS A N   1 
ATOM 780  C CA  . HIS A 1 190 ? 193.083 191.114 158.837 1.00 37.93 ? 190 HIS A CA  1 
ATOM 781  C C   . HIS A 1 190 ? 194.320 191.672 159.524 1.00 33.62 ? 190 HIS A C   1 
ATOM 782  O O   . HIS A 1 190 ? 194.512 191.485 160.730 1.00 42.85 ? 190 HIS A O   1 
ATOM 783  C CB  . HIS A 1 190 ? 191.876 192.016 159.116 1.00 42.39 ? 190 HIS A CB  1 
ATOM 784  C CG  . HIS A 1 190 ? 192.049 193.422 158.636 1.00 40.73 ? 190 HIS A CG  1 
ATOM 785  N ND1 . HIS A 1 190 ? 192.758 193.738 157.497 1.00 44.85 ? 190 HIS A ND1 1 
ATOM 786  C CD2 . HIS A 1 190 ? 191.600 194.597 159.137 1.00 41.50 ? 190 HIS A CD2 1 
ATOM 787  C CE1 . HIS A 1 190 ? 192.743 195.047 157.320 1.00 44.48 ? 190 HIS A CE1 1 
ATOM 788  N NE2 . HIS A 1 190 ? 192.046 195.592 158.300 1.00 42.65 ? 190 HIS A NE2 1 
ATOM 789  N N   . THR A 1 191 ? 195.158 192.357 158.749 1.00 34.10 ? 191 THR A N   1 
ATOM 790  C CA  . THR A 1 191 ? 196.381 192.964 159.255 1.00 41.72 ? 191 THR A CA  1 
ATOM 791  C C   . THR A 1 191 ? 196.461 194.403 158.770 1.00 42.88 ? 191 THR A C   1 
ATOM 792  O O   . THR A 1 191 ? 196.260 194.672 157.582 1.00 44.24 ? 191 THR A O   1 
ATOM 793  C CB  . THR A 1 191 ? 197.621 192.188 158.797 1.00 41.33 ? 191 THR A CB  1 
ATOM 794  O OG1 . THR A 1 191 ? 197.560 190.848 159.297 1.00 42.79 ? 191 THR A OG1 1 
ATOM 795  C CG2 . THR A 1 191 ? 198.888 192.853 159.313 1.00 39.36 ? 191 THR A CG2 1 
ATOM 796  N N   . VAL A 1 192 ? 196.754 195.321 159.687 1.00 40.34 ? 192 VAL A N   1 
ATOM 797  C CA  . VAL A 1 192 ? 196.942 196.730 159.368 1.00 37.48 ? 192 VAL A CA  1 
ATOM 798  C C   . VAL A 1 192 ? 198.372 197.101 159.729 1.00 39.45 ? 192 VAL A C   1 
ATOM 799  O O   . VAL A 1 192 ? 198.797 196.911 160.876 1.00 46.10 ? 192 VAL A O   1 
ATOM 800  C CB  . VAL A 1 192 ? 195.939 197.626 160.111 1.00 41.29 ? 192 VAL A CB  1 
ATOM 801  C CG1 . VAL A 1 192 ? 196.109 199.076 159.685 1.00 45.82 ? 192 VAL A CG1 1 
ATOM 802  C CG2 . VAL A 1 192 ? 194.518 197.153 159.859 1.00 39.03 ? 192 VAL A CG2 1 
ATOM 803  N N   . THR A 1 193 ? 199.112 197.625 158.756 1.00 48.16 ? 193 THR A N   1 
ATOM 804  C CA  . THR A 1 193 ? 200.497 198.031 158.949 1.00 50.71 ? 193 THR A CA  1 
ATOM 805  C C   . THR A 1 193 ? 200.625 199.522 158.680 1.00 49.11 ? 193 THR A C   1 
ATOM 806  O O   . THR A 1 193 ? 200.244 199.999 157.605 1.00 49.10 ? 193 THR A O   1 
ATOM 807  C CB  . THR A 1 193 ? 201.440 197.247 158.031 1.00 52.40 ? 193 THR A CB  1 
ATOM 808  O OG1 . THR A 1 193 ? 201.273 195.842 158.257 1.00 48.44 ? 193 THR A OG1 1 
ATOM 809  C CG2 . THR A 1 193 ? 202.887 197.632 158.302 1.00 51.56 ? 193 THR A CG2 1 
ATOM 810  N N   . THR A 1 194 ? 201.162 200.254 159.657 1.00 46.47 ? 194 THR A N   1 
ATOM 811  C CA  . THR A 1 194 ? 201.395 201.696 159.533 1.00 49.09 ? 194 THR A CA  1 
ATOM 812  C C   . THR A 1 194 ? 202.756 201.988 160.163 1.00 50.70 ? 194 THR A C   1 
ATOM 813  O O   . THR A 1 194 ? 202.855 202.233 161.368 1.00 52.14 ? 194 THR A O   1 
ATOM 814  C CB  . THR A 1 194 ? 200.283 202.503 160.191 1.00 49.30 ? 194 THR A CB  1 
ATOM 815  O OG1 . THR A 1 194 ? 199.011 202.044 159.715 1.00 46.94 ? 194 THR A OG1 1 
ATOM 816  C CG2 . THR A 1 194 ? 200.435 203.981 159.863 1.00 47.45 ? 194 THR A CG2 1 
ATOM 817  N N   . THR A 1 195 ? 203.799 201.959 159.340 1.00 49.04 ? 195 THR A N   1 
ATOM 818  C CA  . THR A 1 195 ? 205.165 202.189 159.788 1.00 53.61 ? 195 THR A CA  1 
ATOM 819  C C   . THR A 1 195 ? 205.683 203.490 159.191 1.00 52.35 ? 195 THR A C   1 
ATOM 820  O O   . THR A 1 195 ? 205.592 203.701 157.977 1.00 49.17 ? 195 THR A O   1 
ATOM 821  C CB  . THR A 1 195 ? 206.078 201.027 159.391 1.00 50.40 ? 195 THR A CB  1 
ATOM 822  O OG1 . THR A 1 195 ? 205.555 199.803 159.921 1.00 52.03 ? 195 THR A OG1 1 
ATOM 823  C CG2 . THR A 1 195 ? 207.482 201.248 159.933 1.00 51.02 ? 195 THR A CG2 1 
ATOM 824  N N   . THR A 1 196 ? 206.222 204.354 160.045 1.00 53.59 ? 196 THR A N   1 
ATOM 825  C CA  . THR A 1 196 ? 206.779 205.634 159.631 1.00 52.66 ? 196 THR A CA  1 
ATOM 826  C C   . THR A 1 196 ? 208.278 205.669 159.890 1.00 54.50 ? 196 THR A C   1 
ATOM 827  O O   . THR A 1 196 ? 208.717 205.457 161.025 1.00 53.08 ? 196 THR A O   1 
ATOM 828  C CB  . THR A 1 196 ? 206.118 206.792 160.383 1.00 55.14 ? 196 THR A CB  1 
ATOM 829  O OG1 . THR A 1 196 ? 204.692 206.665 160.300 1.00 54.11 ? 196 THR A OG1 1 
ATOM 830  C CG2 . THR A 1 196 ? 206.538 208.125 159.783 1.00 55.02 ? 196 THR A CG2 1 
ATOM 831  N N   . LYS A 1 197 ? 209.046 205.946 158.834 1.00 65.56 ? 197 LYS A N   1 
ATOM 832  C CA  . LYS A 1 197 ? 210.512 206.026 158.859 1.00 65.81 ? 197 LYS A CA  1 
ATOM 833  C C   . LYS A 1 197 ? 211.123 204.891 159.681 1.00 65.64 ? 197 LYS A C   1 
ATOM 834  O O   . LYS A 1 197 ? 211.984 205.094 160.540 1.00 64.86 ? 197 LYS A O   1 
ATOM 835  C CB  . LYS A 1 197 ? 211.010 207.396 159.340 1.00 64.87 ? 197 LYS A CB  1 
ATOM 836  C CG  . LYS A 1 197 ? 210.505 207.868 160.698 1.00 62.96 ? 197 LYS A CG  1 
ATOM 837  C CD  . LYS A 1 197 ? 211.115 209.207 161.077 1.00 64.76 ? 197 LYS A CD  1 
ATOM 838  C CE  . LYS A 1 197 ? 210.540 210.335 160.234 1.00 65.57 ? 197 LYS A CE  1 
ATOM 839  N NZ  . LYS A 1 197 ? 209.068 210.469 160.412 1.00 63.84 ? 197 LYS A NZ  1 
ATOM 840  N N   . GLY A 1 198 ? 210.669 203.673 159.398 1.00 60.50 ? 198 GLY A N   1 
ATOM 841  C CA  . GLY A 1 198 ? 211.235 202.494 160.025 1.00 59.33 ? 198 GLY A CA  1 
ATOM 842  C C   . GLY A 1 198 ? 212.540 202.084 159.376 1.00 59.91 ? 198 GLY A C   1 
ATOM 843  O O   . GLY A 1 198 ? 212.562 201.705 158.201 1.00 61.04 ? 198 GLY A O   1 
ATOM 844  N N   . GLU A 1 199 ? 213.635 202.154 160.127 1.00 58.39 ? 199 GLU A N   1 
ATOM 845  C CA  . GLU A 1 199 ? 214.970 201.918 159.596 1.00 60.87 ? 199 GLU A CA  1 
ATOM 846  C C   . GLU A 1 199 ? 215.559 200.649 160.196 1.00 60.52 ? 199 GLU A C   1 
ATOM 847  O O   . GLU A 1 199 ? 215.580 200.488 161.421 1.00 59.17 ? 199 GLU A O   1 
ATOM 848  C CB  . GLU A 1 199 ? 215.887 203.110 159.883 1.00 62.13 ? 199 GLU A CB  1 
ATOM 849  C CG  . GLU A 1 199 ? 215.472 204.393 159.183 1.00 63.39 ? 199 GLU A CG  1 
ATOM 850  C CD  . GLU A 1 199 ? 216.276 205.594 159.643 1.00 64.46 ? 199 GLU A CD  1 
ATOM 851  O OE1 . GLU A 1 199 ? 216.791 205.566 160.780 1.00 61.74 ? 199 GLU A OE1 1 
ATOM 852  O OE2 . GLU A 1 199 ? 216.393 206.565 158.866 1.00 64.33 ? 199 GLU A OE2 1 
ATOM 853  N N   . ASN A 1 200 ? 216.038 199.757 159.325 1.00 68.57 ? 200 ASN A N   1 
ATOM 854  C CA  . ASN A 1 200 ? 216.764 198.550 159.728 1.00 68.12 ? 200 ASN A CA  1 
ATOM 855  C C   . ASN A 1 200 ? 215.949 197.687 160.688 1.00 63.31 ? 200 ASN A C   1 
ATOM 856  O O   . ASN A 1 200 ? 216.479 197.130 161.651 1.00 63.03 ? 200 ASN A O   1 
ATOM 857  C CB  . ASN A 1 200 ? 218.120 198.905 160.341 1.00 65.91 ? 200 ASN A CB  1 
ATOM 858  C CG  . ASN A 1 200 ? 218.963 199.774 159.428 1.00 68.81 ? 200 ASN A CG  1 
ATOM 859  O OD1 . ASN A 1 200 ? 218.938 201.001 159.522 1.00 69.14 ? 200 ASN A OD1 1 
ATOM 860  N ND2 . ASN A 1 200 ? 219.715 199.139 158.536 1.00 67.93 ? 200 ASN A ND2 1 
ATOM 861  N N   . PHE A 1 201 ? 214.652 197.560 160.421 1.00 51.68 ? 201 PHE A N   1 
ATOM 862  C CA  . PHE A 1 201 ? 213.766 196.782 161.272 1.00 54.38 ? 201 PHE A CA  1 
ATOM 863  C C   . PHE A 1 201 ? 213.142 195.639 160.482 1.00 52.48 ? 201 PHE A C   1 
ATOM 864  O O   . PHE A 1 201 ? 212.912 195.747 159.274 1.00 53.11 ? 201 PHE A O   1 
ATOM 865  C CB  . PHE A 1 201 ? 212.675 197.668 161.900 1.00 55.05 ? 201 PHE A CB  1 
ATOM 866  C CG  . PHE A 1 201 ? 211.424 197.797 161.073 1.00 56.16 ? 201 PHE A CG  1 
ATOM 867  C CD1 . PHE A 1 201 ? 211.299 198.810 160.138 1.00 52.21 ? 201 PHE A CD1 1 
ATOM 868  C CD2 . PHE A 1 201 ? 210.358 196.926 161.254 1.00 54.54 ? 201 PHE A CD2 1 
ATOM 869  C CE1 . PHE A 1 201 ? 210.148 198.939 159.385 1.00 50.84 ? 201 PHE A CE1 1 
ATOM 870  C CE2 . PHE A 1 201 ? 209.207 197.050 160.501 1.00 51.94 ? 201 PHE A CE2 1 
ATOM 871  C CZ  . PHE A 1 201 ? 209.102 198.058 159.566 1.00 52.23 ? 201 PHE A CZ  1 
ATOM 872  N N   . THR A 1 202 ? 212.873 194.541 161.180 1.00 52.32 ? 202 THR A N   1 
ATOM 873  C CA  . THR A 1 202 ? 212.283 193.347 160.590 1.00 53.03 ? 202 THR A CA  1 
ATOM 874  C C   . THR A 1 202 ? 210.851 193.195 161.081 1.00 50.78 ? 202 THR A C   1 
ATOM 875  O O   . THR A 1 202 ? 210.595 193.244 162.288 1.00 53.86 ? 202 THR A O   1 
ATOM 876  C CB  . THR A 1 202 ? 213.097 192.100 160.943 1.00 50.28 ? 202 THR A CB  1 
ATOM 877  O OG1 . THR A 1 202 ? 214.437 192.247 160.455 1.00 53.98 ? 202 THR A OG1 1 
ATOM 878  C CG2 . THR A 1 202 ? 212.471 190.860 160.323 1.00 50.97 ? 202 THR A CG2 1 
ATOM 879  N N   . GLU A 1 203 ? 209.925 193.013 160.145 1.00 51.17 ? 203 GLU A N   1 
ATOM 880  C CA  . GLU A 1 203 ? 208.512 192.835 160.451 1.00 48.56 ? 203 GLU A CA  1 
ATOM 881  C C   . GLU A 1 203 ? 208.087 191.424 160.074 1.00 50.88 ? 203 GLU A C   1 
ATOM 882  O O   . GLU A 1 203 ? 208.286 190.996 158.932 1.00 53.33 ? 203 GLU A O   1 
ATOM 883  C CB  . GLU A 1 203 ? 207.658 193.862 159.705 1.00 52.89 ? 203 GLU A CB  1 
ATOM 884  C CG  . GLU A 1 203 ? 206.177 193.786 160.031 1.00 56.11 ? 203 GLU A CG  1 
ATOM 885  C CD  . GLU A 1 203 ? 205.368 194.846 159.312 1.00 55.62 ? 203 GLU A CD  1 
ATOM 886  O OE1 . GLU A 1 203 ? 205.959 195.619 158.530 1.00 53.41 ? 203 GLU A OE1 1 
ATOM 887  O OE2 . GLU A 1 203 ? 204.140 194.904 159.530 1.00 55.09 ? 203 GLU A OE2 1 
ATOM 888  N N   . THR A 1 204 ? 207.506 190.706 161.032 1.00 52.68 ? 204 THR A N   1 
ATOM 889  C CA  . THR A 1 204 ? 207.026 189.348 160.812 1.00 54.63 ? 204 THR A CA  1 
ATOM 890  C C   . THR A 1 204 ? 205.563 189.265 161.219 1.00 51.93 ? 204 THR A C   1 
ATOM 891  O O   . THR A 1 204 ? 205.218 189.558 162.368 1.00 57.57 ? 204 THR A O   1 
ATOM 892  C CB  . THR A 1 204 ? 207.853 188.329 161.604 1.00 53.25 ? 204 THR A CB  1 
ATOM 893  O OG1 . THR A 1 204 ? 209.230 188.426 161.219 1.00 55.87 ? 204 THR A OG1 1 
ATOM 894  C CG2 . THR A 1 204 ? 207.356 186.918 161.336 1.00 52.63 ? 204 THR A CG2 1 
ATOM 895  N N   . ASP A 1 205 ? 204.713 188.849 160.282 1.00 44.95 ? 205 ASP A N   1 
ATOM 896  C CA  . ASP A 1 205 ? 203.273 188.727 160.503 1.00 45.63 ? 205 ASP A CA  1 
ATOM 897  C C   . ASP A 1 205 ? 202.833 187.359 159.992 1.00 48.71 ? 205 ASP A C   1 
ATOM 898  O O   . ASP A 1 205 ? 202.606 187.180 158.792 1.00 55.01 ? 205 ASP A O   1 
ATOM 899  C CB  . ASP A 1 205 ? 202.507 189.847 159.803 1.00 51.54 ? 205 ASP A CB  1 
ATOM 900  C CG  . ASP A 1 205 ? 202.705 191.198 160.465 1.00 56.86 ? 205 ASP A CG  1 
ATOM 901  O OD1 . ASP A 1 205 ? 203.192 191.238 161.613 1.00 54.93 ? 205 ASP A OD1 1 
ATOM 902  O OD2 . ASP A 1 205 ? 202.373 192.223 159.834 1.00 56.78 ? 205 ASP A OD2 1 
ATOM 903  N N   . ILE A 1 206 ? 202.715 186.395 160.901 1.00 41.34 ? 206 ILE A N   1 
ATOM 904  C CA  . ILE A 1 206 ? 202.289 185.040 160.573 1.00 44.19 ? 206 ILE A CA  1 
ATOM 905  C C   . ILE A 1 206 ? 200.945 184.787 161.239 1.00 39.49 ? 206 ILE A C   1 
ATOM 906  O O   . ILE A 1 206 ? 200.805 184.958 162.456 1.00 43.70 ? 206 ILE A O   1 
ATOM 907  C CB  . ILE A 1 206 ? 203.327 183.996 161.018 1.00 37.28 ? 206 ILE A CB  1 
ATOM 908  C CG1 . ILE A 1 206 ? 204.697 184.315 160.417 1.00 41.77 ? 206 ILE A CG1 1 
ATOM 909  C CG2 . ILE A 1 206 ? 202.881 182.599 160.615 1.00 33.21 ? 206 ILE A CG2 1 
ATOM 910  C CD1 . ILE A 1 206 ? 205.779 183.338 160.818 1.00 42.50 ? 206 ILE A CD1 1 
ATOM 911  N N   . LYS A 1 207 ? 199.957 184.385 160.441 1.00 36.66 ? 207 LYS A N   1 
ATOM 912  C CA  . LYS A 1 207 ? 198.616 184.064 160.930 1.00 35.07 ? 207 LYS A CA  1 
ATOM 913  C C   . LYS A 1 207 ? 198.245 182.697 160.365 1.00 37.98 ? 207 LYS A C   1 
ATOM 914  O O   . LYS A 1 207 ? 197.655 182.599 159.285 1.00 43.11 ? 207 LYS A O   1 
ATOM 915  C CB  . LYS A 1 207 ? 197.612 185.142 160.536 1.00 40.96 ? 207 LYS A CB  1 
ATOM 916  C CG  . LYS A 1 207 ? 197.848 186.478 161.215 1.00 41.93 ? 207 LYS A CG  1 
ATOM 917  C CD  . LYS A 1 207 ? 196.765 187.479 160.861 1.00 39.80 ? 207 LYS A CD  1 
ATOM 918  C CE  . LYS A 1 207 ? 196.944 188.768 161.641 1.00 40.21 ? 207 LYS A CE  1 
ATOM 919  N NZ  . LYS A 1 207 ? 198.127 189.539 161.169 1.00 41.69 ? 207 LYS A NZ  1 
ATOM 920  N N   . MET A 1 208 ? 198.596 181.644 161.096 1.00 49.38 ? 208 MET A N   1 
ATOM 921  C CA  . MET A 1 208 ? 198.213 180.298 160.697 1.00 46.82 ? 208 MET A CA  1 
ATOM 922  C C   . MET A 1 208 ? 196.718 180.098 160.906 1.00 42.45 ? 208 MET A C   1 
ATOM 923  O O   . MET A 1 208 ? 196.157 180.512 161.923 1.00 51.23 ? 208 MET A O   1 
ATOM 924  C CB  . MET A 1 208 ? 198.988 179.261 161.510 1.00 47.70 ? 208 MET A CB  1 
ATOM 925  C CG  . MET A 1 208 ? 200.480 179.234 161.227 1.00 51.54 ? 208 MET A CG  1 
ATOM 926  S SD  . MET A 1 208 ? 201.353 178.054 162.275 1.00 68.67 ? 208 MET A SD  1 
ATOM 927  C CE  . MET A 1 208 ? 203.044 178.313 161.741 1.00 54.38 ? 208 MET A CE  1 
ATOM 928  N N   . MET A 1 209 ? 196.069 179.467 159.929 1.00 44.54 ? 209 MET A N   1 
ATOM 929  C CA  . MET A 1 209 ? 194.624 179.225 159.963 1.00 45.03 ? 209 MET A CA  1 
ATOM 930  C C   . MET A 1 209 ? 194.388 177.831 159.382 1.00 51.23 ? 209 MET A C   1 
ATOM 931  O O   . MET A 1 209 ? 194.250 177.671 158.167 1.00 56.05 ? 209 MET A O   1 
ATOM 932  C CB  . MET A 1 209 ? 193.886 180.307 159.181 1.00 52.34 ? 209 MET A CB  1 
ATOM 933  C CG  . MET A 1 209 ? 192.460 180.568 159.624 1.00 52.52 ? 209 MET A CG  1 
ATOM 934  S SD  . MET A 1 209 ? 192.363 181.673 161.045 1.00 58.69 ? 209 MET A SD  1 
ATOM 935  C CE  . MET A 1 209 ? 190.607 182.017 161.092 1.00 43.13 ? 209 MET A CE  1 
ATOM 936  N N   . GLU A 1 210 ? 194.345 176.827 160.256 1.00 47.20 ? 210 GLU A N   1 
ATOM 937  C CA  . GLU A 1 210 ? 194.219 175.437 159.837 1.00 50.27 ? 210 GLU A CA  1 
ATOM 938  C C   . GLU A 1 210 ? 193.103 174.759 160.616 1.00 43.23 ? 210 GLU A C   1 
ATOM 939  O O   . GLU A 1 210 ? 193.061 174.848 161.846 1.00 42.12 ? 210 GLU A O   1 
ATOM 940  C CB  . GLU A 1 210 ? 195.535 174.677 160.035 1.00 48.50 ? 210 GLU A CB  1 
ATOM 941  C CG  . GLU A 1 210 ? 196.563 174.930 158.949 1.00 51.76 ? 210 GLU A CG  1 
ATOM 942  C CD  . GLU A 1 210 ? 197.442 173.723 158.694 1.00 53.42 ? 210 GLU A CD  1 
ATOM 943  O OE1 . GLU A 1 210 ? 197.550 172.864 159.595 1.00 55.46 ? 210 GLU A OE1 1 
ATOM 944  O OE2 . GLU A 1 210 ? 198.020 173.630 157.591 1.00 50.29 ? 210 GLU A OE2 1 
ATOM 945  N N   . ARG A 1 211 ? 192.206 174.084 159.893 1.00 45.35 ? 211 ARG A N   1 
ATOM 946  C CA  . ARG A 1 211 ? 191.119 173.309 160.496 1.00 46.47 ? 211 ARG A CA  1 
ATOM 947  C C   . ARG A 1 211 ? 190.305 174.167 161.462 1.00 46.82 ? 211 ARG A C   1 
ATOM 948  O O   . ARG A 1 211 ? 189.852 173.706 162.511 1.00 46.12 ? 211 ARG A O   1 
ATOM 949  C CB  . ARG A 1 211 ? 191.666 172.061 161.191 1.00 47.45 ? 211 ARG A CB  1 
ATOM 950  C CG  . ARG A 1 211 ? 190.779 170.827 161.093 1.00 45.59 ? 211 ARG A CG  1 
ATOM 951  C CD  . ARG A 1 211 ? 191.497 169.608 161.656 1.00 45.05 ? 211 ARG A CD  1 
ATOM 952  N NE  . ARG A 1 211 ? 190.595 168.717 162.374 1.00 48.98 ? 211 ARG A NE  1 
ATOM 953  C CZ  . ARG A 1 211 ? 190.990 167.692 163.115 1.00 50.76 ? 211 ARG A CZ  1 
ATOM 954  N NH1 . ARG A 1 211 ? 192.271 167.397 163.261 1.00 49.50 ? 211 ARG A NH1 1 
ATOM 955  N NH2 . ARG A 1 211 ? 190.076 166.946 163.731 1.00 47.89 ? 211 ARG A NH2 1 
ATOM 956  N N   . VAL A 1 212 ? 190.106 175.433 161.090 1.00 48.66 ? 212 VAL A N   1 
ATOM 957  C CA  . VAL A 1 212 ? 189.533 176.415 162.006 1.00 45.24 ? 212 VAL A CA  1 
ATOM 958  C C   . VAL A 1 212 ? 188.033 176.208 162.176 1.00 46.06 ? 212 VAL A C   1 
ATOM 959  O O   . VAL A 1 212 ? 187.513 176.282 163.293 1.00 51.41 ? 212 VAL A O   1 
ATOM 960  C CB  . VAL A 1 212 ? 189.862 177.840 161.529 1.00 45.29 ? 212 VAL A CB  1 
ATOM 961  C CG1 . VAL A 1 212 ? 189.038 178.861 162.293 1.00 45.67 ? 212 VAL A CG1 1 
ATOM 962  C CG2 . VAL A 1 212 ? 191.334 178.110 161.726 1.00 47.61 ? 212 VAL A CG2 1 
ATOM 963  N N   . VAL A 1 213 ? 187.309 176.006 161.078 1.00 40.84 ? 213 VAL A N   1 
ATOM 964  C CA  . VAL A 1 213 ? 185.899 175.628 161.114 1.00 41.21 ? 213 VAL A CA  1 
ATOM 965  C C   . VAL A 1 213 ? 185.748 174.397 160.233 1.00 47.58 ? 213 VAL A C   1 
ATOM 966  O O   . VAL A 1 213 ? 185.969 174.465 159.019 1.00 48.73 ? 213 VAL A O   1 
ATOM 967  C CB  . VAL A 1 213 ? 184.980 176.769 160.647 1.00 44.20 ? 213 VAL A CB  1 
ATOM 968  C CG1 . VAL A 1 213 ? 183.523 176.407 160.884 1.00 41.51 ? 213 VAL A CG1 1 
ATOM 969  C CG2 . VAL A 1 213 ? 185.328 178.068 161.361 1.00 44.98 ? 213 VAL A CG2 1 
ATOM 970  N N   . GLU A 1 214 ? 185.327 173.282 160.824 1.00 49.20 ? 214 GLU A N   1 
ATOM 971  C CA  . GLU A 1 214 ? 185.150 172.071 160.031 1.00 43.81 ? 214 GLU A CA  1 
ATOM 972  C C   . GLU A 1 214 ? 183.736 171.968 159.480 1.00 42.04 ? 214 GLU A C   1 
ATOM 973  O O   . GLU A 1 214 ? 183.556 171.596 158.318 1.00 48.73 ? 214 GLU A O   1 
ATOM 974  C CB  . GLU A 1 214 ? 185.493 170.823 160.852 1.00 47.54 ? 214 GLU A CB  1 
ATOM 975  C CG  . GLU A 1 214 ? 186.978 170.525 160.968 1.00 44.93 ? 214 GLU A CG  1 
ATOM 976  C CD  . GLU A 1 214 ? 187.250 169.233 161.712 1.00 49.26 ? 214 GLU A CD  1 
ATOM 977  O OE1 . GLU A 1 214 ? 186.401 168.831 162.537 1.00 50.88 ? 214 GLU A OE1 1 
ATOM 978  O OE2 . GLU A 1 214 ? 188.312 168.619 161.481 1.00 51.10 ? 214 GLU A OE2 1 
ATOM 979  N N   . GLN A 1 215 ? 182.729 172.290 160.287 1.00 37.13 ? 215 GLN A N   1 
ATOM 980  C CA  . GLN A 1 215 ? 181.345 172.290 159.841 1.00 36.66 ? 215 GLN A CA  1 
ATOM 981  C C   . GLN A 1 215 ? 180.619 173.484 160.439 1.00 42.88 ? 215 GLN A C   1 
ATOM 982  O O   . GLN A 1 215 ? 180.953 173.948 161.532 1.00 43.51 ? 215 GLN A O   1 
ATOM 983  C CB  . GLN A 1 215 ? 180.639 170.986 160.238 1.00 40.01 ? 215 GLN A CB  1 
ATOM 984  C CG  . GLN A 1 215 ? 180.946 169.818 159.322 1.00 38.49 ? 215 GLN A CG  1 
ATOM 985  C CD  . GLN A 1 215 ? 182.228 169.104 159.698 1.00 43.54 ? 215 GLN A CD  1 
ATOM 986  O OE1 . GLN A 1 215 ? 182.564 168.982 160.876 1.00 44.42 ? 215 GLN A OE1 1 
ATOM 987  N NE2 . GLN A 1 215 ? 182.961 168.645 158.694 1.00 37.51 ? 215 GLN A NE2 1 
ATOM 988  N N   . MET A 1 216 ? 179.618 173.974 159.712 1.00 48.32 ? 216 MET A N   1 
ATOM 989  C CA  . MET A 1 216 ? 178.818 175.100 160.174 1.00 43.39 ? 216 MET A CA  1 
ATOM 990  C C   . MET A 1 216 ? 177.494 175.085 159.426 1.00 40.31 ? 216 MET A C   1 
ATOM 991  O O   . MET A 1 216 ? 177.470 174.889 158.210 1.00 42.89 ? 216 MET A O   1 
ATOM 992  C CB  . MET A 1 216 ? 179.553 176.431 159.973 1.00 41.54 ? 216 MET A CB  1 
ATOM 993  C CG  . MET A 1 216 ? 178.929 177.602 160.715 1.00 44.60 ? 216 MET A CG  1 
ATOM 994  S SD  . MET A 1 216 ? 180.053 178.997 160.923 1.00 53.13 ? 216 MET A SD  1 
ATOM 995  C CE  . MET A 1 216 ? 181.074 178.845 159.460 1.00 49.74 ? 216 MET A CE  1 
ATOM 996  N N   . CYS A 1 217 ? 176.402 175.298 160.164 1.00 43.52 ? 217 CYS A N   1 
ATOM 997  C CA  . CYS A 1 217 ? 175.053 175.351 159.594 1.00 39.89 ? 217 CYS A CA  1 
ATOM 998  C C   . CYS A 1 217 ? 174.719 174.092 158.798 1.00 39.07 ? 217 CYS A C   1 
ATOM 999  O O   . CYS A 1 217 ? 174.110 174.155 157.728 1.00 39.65 ? 217 CYS A O   1 
ATOM 1000 C CB  . CYS A 1 217 ? 174.881 176.598 158.726 1.00 39.68 ? 217 CYS A CB  1 
ATOM 1001 S SG  . CYS A 1 217 ? 175.603 178.090 159.430 1.00 56.99 ? 217 CYS A SG  1 
ATOM 1002 N N   . ILE A 1 218 ? 175.113 172.936 159.327 1.00 39.60 ? 218 ILE A N   1 
ATOM 1003 C CA  . ILE A 1 218 ? 174.863 171.655 158.665 1.00 40.89 ? 218 ILE A CA  1 
ATOM 1004 C C   . ILE A 1 218 ? 173.489 171.186 159.134 1.00 37.93 ? 218 ILE A C   1 
ATOM 1005 O O   . ILE A 1 218 ? 173.342 170.555 160.181 1.00 43.77 ? 218 ILE A O   1 
ATOM 1006 C CB  . ILE A 1 218 ? 175.957 170.632 158.958 1.00 38.54 ? 218 ILE A CB  1 
ATOM 1007 C CG1 . ILE A 1 218 ? 177.339 171.235 158.699 1.00 40.26 ? 218 ILE A CG1 1 
ATOM 1008 C CG2 . ILE A 1 218 ? 175.752 169.382 158.120 1.00 33.45 ? 218 ILE A CG2 1 
ATOM 1009 C CD1 . ILE A 1 218 ? 177.504 171.834 157.329 1.00 36.50 ? 218 ILE A CD1 1 
ATOM 1010 N N   . THR A 1 219 ? 172.466 171.504 158.344 1.00 27.02 ? 219 THR A N   1 
ATOM 1011 C CA  . THR A 1 219 ? 171.102 171.051 158.614 1.00 30.50 ? 219 THR A CA  1 
ATOM 1012 C C   . THR A 1 219 ? 170.917 169.718 157.902 1.00 34.48 ? 219 THR A C   1 
ATOM 1013 O O   . THR A 1 219 ? 170.441 169.652 156.768 1.00 35.24 ? 219 THR A O   1 
ATOM 1014 C CB  . THR A 1 219 ? 170.082 172.085 158.155 1.00 33.52 ? 219 THR A CB  1 
ATOM 1015 O OG1 . THR A 1 219 ? 170.441 173.374 158.670 1.00 36.53 ? 219 THR A OG1 1 
ATOM 1016 C CG2 . THR A 1 219 ? 168.693 171.717 158.654 1.00 32.51 ? 219 THR A CG2 1 
ATOM 1017 N N   . GLN A 1 220 ? 171.304 168.641 158.578 1.00 27.57 ? 220 GLN A N   1 
ATOM 1018 C CA  . GLN A 1 220 ? 171.296 167.304 158.003 1.00 24.68 ? 220 GLN A CA  1 
ATOM 1019 C C   . GLN A 1 220 ? 170.281 166.433 158.729 1.00 19.70 ? 220 GLN A C   1 
ATOM 1020 O O   . GLN A 1 220 ? 170.324 166.316 159.958 1.00 31.43 ? 220 GLN A O   1 
ATOM 1021 C CB  . GLN A 1 220 ? 172.687 166.670 158.082 1.00 26.51 ? 220 GLN A CB  1 
ATOM 1022 C CG  . GLN A 1 220 ? 172.908 165.531 157.105 1.00 31.04 ? 220 GLN A CG  1 
ATOM 1023 C CD  . GLN A 1 220 ? 174.377 165.232 156.885 1.00 32.04 ? 220 GLN A CD  1 
ATOM 1024 O OE1 . GLN A 1 220 ? 175.081 164.818 157.805 1.00 34.98 ? 220 GLN A OE1 1 
ATOM 1025 N NE2 . GLN A 1 220 ? 174.846 165.439 155.661 1.00 27.30 ? 220 GLN A NE2 1 
ATOM 1026 N N   . TYR A 1 221 ? 169.374 165.826 157.970 1.00 18.91 ? 221 TYR A N   1 
ATOM 1027 C CA  . TYR A 1 221 ? 168.406 164.877 158.503 1.00 26.03 ? 221 TYR A CA  1 
ATOM 1028 C C   . TYR A 1 221 ? 168.835 163.480 158.079 1.00 28.67 ? 221 TYR A C   1 
ATOM 1029 O O   . TYR A 1 221 ? 168.983 163.209 156.882 1.00 27.26 ? 221 TYR A O   1 
ATOM 1030 C CB  . TYR A 1 221 ? 166.990 165.183 158.012 1.00 31.08 ? 221 TYR A CB  1 
ATOM 1031 C CG  . TYR A 1 221 ? 166.507 166.585 158.318 1.00 34.35 ? 221 TYR A CG  1 
ATOM 1032 C CD1 . TYR A 1 221 ? 167.092 167.344 159.324 1.00 32.87 ? 221 TYR A CD1 1 
ATOM 1033 C CD2 . TYR A 1 221 ? 165.459 167.147 157.602 1.00 32.90 ? 221 TYR A CD2 1 
ATOM 1034 C CE1 . TYR A 1 221 ? 166.655 168.624 159.601 1.00 32.11 ? 221 TYR A CE1 1 
ATOM 1035 C CE2 . TYR A 1 221 ? 165.012 168.426 157.874 1.00 31.97 ? 221 TYR A CE2 1 
ATOM 1036 C CZ  . TYR A 1 221 ? 165.613 169.159 158.875 1.00 34.85 ? 221 TYR A CZ  1 
ATOM 1037 O OH  . TYR A 1 221 ? 165.173 170.433 159.150 1.00 40.38 ? 221 TYR A OH  1 
ATOM 1038 N N   . GLN A 1 222 ? 169.036 162.600 159.055 1.00 28.93 ? 222 GLN A N   1 
ATOM 1039 C CA  . GLN A 1 222 ? 169.572 161.267 158.818 1.00 19.01 ? 222 GLN A CA  1 
ATOM 1040 C C   . GLN A 1 222 ? 168.564 160.219 159.263 1.00 20.66 ? 222 GLN A C   1 
ATOM 1041 O O   . GLN A 1 222 ? 168.000 160.319 160.357 1.00 30.48 ? 222 GLN A O   1 
ATOM 1042 C CB  . GLN A 1 222 ? 170.896 161.072 159.558 1.00 23.57 ? 222 GLN A CB  1 
ATOM 1043 C CG  . GLN A 1 222 ? 172.037 161.928 159.041 1.00 31.19 ? 222 GLN A CG  1 
ATOM 1044 C CD  . GLN A 1 222 ? 173.341 161.649 159.761 1.00 31.12 ? 222 GLN A CD  1 
ATOM 1045 O OE1 . GLN A 1 222 ? 173.377 160.892 160.731 1.00 25.97 ? 222 GLN A OE1 1 
ATOM 1046 N NE2 . GLN A 1 222 ? 174.420 162.261 159.291 1.00 30.01 ? 222 GLN A NE2 1 
ATOM 1047 N N   . ARG A 1 223 ? 168.342 159.218 158.413 1.00 26.00 ? 223 ARG A N   1 
ATOM 1048 C CA  . ARG A 1 223 ? 167.483 158.080 158.742 1.00 34.43 ? 223 ARG A CA  1 
ATOM 1049 C C   . ARG A 1 223 ? 168.164 156.828 158.198 1.00 30.07 ? 223 ARG A C   1 
ATOM 1050 O O   . ARG A 1 223 ? 168.146 156.586 156.987 1.00 23.53 ? 223 ARG A O   1 
ATOM 1051 C CB  . ARG A 1 223 ? 166.082 158.247 158.168 1.00 31.74 ? 223 ARG A CB  1 
ATOM 1052 C CG  . ARG A 1 223 ? 165.211 157.010 158.310 1.00 30.02 ? 223 ARG A CG  1 
ATOM 1053 C CD  . ARG A 1 223 ? 163.850 157.215 157.671 1.00 34.03 ? 223 ARG A CD  1 
ATOM 1054 N NE  . ARG A 1 223 ? 162.935 157.929 158.553 1.00 41.45 ? 223 ARG A NE  1 
ATOM 1055 C CZ  . ARG A 1 223 ? 162.162 157.346 159.459 1.00 40.46 ? 223 ARG A CZ  1 
ATOM 1056 N NH1 . ARG A 1 223 ? 162.168 156.035 159.632 1.00 32.84 ? 223 ARG A NH1 1 
ATOM 1057 N NH2 . ARG A 1 223 ? 161.364 158.099 160.211 1.00 38.48 ? 223 ARG A NH2 1 
ATOM 1058 N N   . GLU A 1 224 ? 168.762 156.043 159.097 1.00 37.17 ? 224 GLU A N   1 
ATOM 1059 C CA  . GLU A 1 224 ? 169.500 154.833 158.728 1.00 35.63 ? 224 GLU A CA  1 
ATOM 1060 C C   . GLU A 1 224 ? 170.592 155.144 157.707 1.00 31.88 ? 224 GLU A C   1 
ATOM 1061 O O   . GLU A 1 224 ? 170.860 154.358 156.797 1.00 30.40 ? 224 GLU A O   1 
ATOM 1062 C CB  . GLU A 1 224 ? 168.559 153.746 158.205 1.00 36.99 ? 224 GLU A CB  1 
ATOM 1063 C CG  . GLU A 1 224 ? 167.321 153.535 159.059 1.00 38.56 ? 224 GLU A CG  1 
ATOM 1064 C CD  . GLU A 1 224 ? 166.193 152.873 158.293 1.00 39.04 ? 224 GLU A CD  1 
ATOM 1065 O OE1 . GLU A 1 224 ? 166.480 152.015 157.433 1.00 44.99 ? 224 GLU A OE1 1 
ATOM 1066 O OE2 . GLU A 1 224 ? 165.019 153.213 158.550 1.00 37.17 ? 224 GLU A OE2 1 
ATOM 1067 N N   . SER A 1 225 ? 171.232 156.298 157.866 1.00 30.11 ? 225 SER A N   1 
ATOM 1068 C CA  . SER A 1 225 ? 172.212 156.797 156.917 1.00 28.70 ? 225 SER A CA  1 
ATOM 1069 C C   . SER A 1 225 ? 173.544 157.042 157.615 1.00 29.20 ? 225 SER A C   1 
ATOM 1070 O O   . SER A 1 225 ? 173.662 156.942 158.839 1.00 39.53 ? 225 SER A O   1 
ATOM 1071 C CB  . SER A 1 225 ? 171.717 158.084 156.247 1.00 30.27 ? 225 SER A CB  1 
ATOM 1072 O OG  . SER A 1 225 ? 170.518 157.854 155.528 1.00 37.64 ? 225 SER A OG  1 
ATOM 1073 N N   . GLN A 1 226 ? 174.558 157.361 156.815 1.00 33.40 ? 226 GLN A N   1 
ATOM 1074 C CA  . GLN A 1 226 ? 175.899 157.604 157.326 1.00 32.84 ? 226 GLN A CA  1 
ATOM 1075 C C   . GLN A 1 226 ? 176.480 158.845 156.668 1.00 32.49 ? 226 GLN A C   1 
ATOM 1076 O O   . GLN A 1 226 ? 176.305 159.060 155.465 1.00 32.50 ? 226 GLN A O   1 
ATOM 1077 C CB  . GLN A 1 226 ? 176.819 156.401 157.080 1.00 20.31 ? 226 GLN A CB  1 
ATOM 1078 C CG  . GLN A 1 226 ? 176.521 155.198 157.959 1.00 24.05 ? 226 GLN A CG  1 
ATOM 1079 C CD  . GLN A 1 226 ? 175.391 154.345 157.416 1.00 30.51 ? 226 GLN A CD  1 
ATOM 1080 O OE1 . GLN A 1 226 ? 175.243 154.189 156.204 1.00 31.21 ? 226 GLN A OE1 1 
ATOM 1081 N NE2 . GLN A 1 226 ? 174.584 153.792 158.313 1.00 34.29 ? 226 GLN A NE2 1 
ATOM 1082 N N   . ALA A 1 227 ? 177.168 159.660 157.465 1.00 24.60 ? 227 ALA A N   1 
ATOM 1083 C CA  . ALA A 1 227 ? 177.863 160.842 156.975 1.00 21.13 ? 227 ALA A CA  1 
ATOM 1084 C C   . ALA A 1 227 ? 179.280 160.839 157.525 1.00 27.62 ? 227 ALA A C   1 
ATOM 1085 O O   . ALA A 1 227 ? 179.478 160.688 158.735 1.00 26.65 ? 227 ALA A O   1 
ATOM 1086 C CB  . ALA A 1 227 ? 177.136 162.127 157.379 1.00 25.28 ? 227 ALA A CB  1 
ATOM 1087 N N   . TYR A 1 228 ? 180.259 161.006 156.640 1.00 37.96 ? 228 TYR A N   1 
ATOM 1088 C CA  . TYR A 1 228 ? 181.669 160.986 157.008 1.00 32.61 ? 228 TYR A CA  1 
ATOM 1089 C C   . TYR A 1 228 ? 182.295 162.318 156.624 1.00 28.12 ? 228 TYR A C   1 
ATOM 1090 O O   . TYR A 1 228 ? 182.248 162.716 155.455 1.00 41.58 ? 228 TYR A O   1 
ATOM 1091 C CB  . TYR A 1 228 ? 182.398 159.828 156.324 1.00 24.71 ? 228 TYR A CB  1 
ATOM 1092 C CG  . TYR A 1 228 ? 181.922 158.463 156.765 1.00 26.42 ? 228 TYR A CG  1 
ATOM 1093 C CD1 . TYR A 1 228 ? 180.786 157.890 156.210 1.00 24.15 ? 228 TYR A CD1 1 
ATOM 1094 C CD2 . TYR A 1 228 ? 182.608 157.749 157.738 1.00 29.54 ? 228 TYR A CD2 1 
ATOM 1095 C CE1 . TYR A 1 228 ? 180.347 156.643 156.611 1.00 30.89 ? 228 TYR A CE1 1 
ATOM 1096 C CE2 . TYR A 1 228 ? 182.177 156.501 158.144 1.00 32.18 ? 228 TYR A CE2 1 
ATOM 1097 C CZ  . TYR A 1 228 ? 181.045 155.954 157.578 1.00 30.31 ? 228 TYR A CZ  1 
ATOM 1098 O OH  . TYR A 1 228 ? 180.610 154.711 157.979 1.00 33.57 ? 228 TYR A OH  1 
ATOM 1099 N N   . TYR A 1 229 ? 182.883 162.998 157.602 1.00 21.12 ? 229 TYR A N   1 
ATOM 1100 C CA  . TYR A 1 229 ? 183.497 164.298 157.370 1.00 17.80 ? 229 TYR A CA  1 
ATOM 1101 C C   . TYR A 1 229 ? 185.008 164.233 157.558 1.00 24.83 ? 229 TYR A C   1 
ATOM 1102 O O   . TYR A 1 229 ? 185.494 163.843 158.619 1.00 35.68 ? 229 TYR A O   1 
ATOM 1103 C CB  . TYR A 1 229 ? 182.894 165.349 158.305 1.00 29.15 ? 229 TYR A CB  1 
ATOM 1104 C CG  . TYR A 1 229 ? 181.400 165.527 158.148 1.00 32.70 ? 229 TYR A CG  1 
ATOM 1105 C CD1 . TYR A 1 229 ? 180.882 166.452 157.251 1.00 25.81 ? 229 TYR A CD1 1 
ATOM 1106 C CD2 . TYR A 1 229 ? 180.508 164.773 158.899 1.00 26.63 ? 229 TYR A CD2 1 
ATOM 1107 C CE1 . TYR A 1 229 ? 179.519 166.619 157.104 1.00 23.56 ? 229 TYR A CE1 1 
ATOM 1108 C CE2 . TYR A 1 229 ? 179.143 164.932 158.759 1.00 23.50 ? 229 TYR A CE2 1 
ATOM 1109 C CZ  . TYR A 1 229 ? 178.654 165.856 157.861 1.00 31.98 ? 229 TYR A CZ  1 
ATOM 1110 O OH  . TYR A 1 229 ? 177.296 166.019 157.718 1.00 37.18 ? 229 TYR A OH  1 
ATOM 1111 N N   . GLY B 1 92  ? 108.552 166.395 157.790 1.00 20.68 ? 92  GLY B N   1 
ATOM 1112 C CA  . GLY B 1 92  ? 109.400 165.270 158.134 1.00 21.41 ? 92  GLY B CA  1 
ATOM 1113 C C   . GLY B 1 92  ? 110.578 165.101 157.194 1.00 23.11 ? 92  GLY B C   1 
ATOM 1114 O O   . GLY B 1 92  ? 110.797 164.022 156.646 1.00 20.48 ? 92  GLY B O   1 
ATOM 1115 N N   . TRP B 1 93  ? 111.338 166.176 157.008 1.00 18.12 ? 93  TRP B N   1 
ATOM 1116 C CA  . TRP B 1 93  ? 112.491 166.161 156.127 1.00 8.04  ? 93  TRP B CA  1 
ATOM 1117 C C   . TRP B 1 93  ? 113.726 165.672 156.881 1.00 13.07 ? 93  TRP B C   1 
ATOM 1118 O O   . TRP B 1 93  ? 113.673 165.334 158.066 1.00 20.48 ? 93  TRP B O   1 
ATOM 1119 C CB  . TRP B 1 93  ? 112.722 167.548 155.529 1.00 14.88 ? 93  TRP B CB  1 
ATOM 1120 C CG  . TRP B 1 93  ? 112.843 168.631 156.557 1.00 13.87 ? 93  TRP B CG  1 
ATOM 1121 C CD1 . TRP B 1 93  ? 111.832 169.384 157.076 1.00 14.01 ? 93  TRP B CD1 1 
ATOM 1122 C CD2 . TRP B 1 93  ? 114.046 169.082 157.192 1.00 18.34 ? 93  TRP B CD2 1 
ATOM 1123 N NE1 . TRP B 1 93  ? 112.329 170.277 157.994 1.00 12.85 ? 93  TRP B NE1 1 
ATOM 1124 C CE2 . TRP B 1 93  ? 113.686 170.112 158.082 1.00 14.76 ? 93  TRP B CE2 1 
ATOM 1125 C CE3 . TRP B 1 93  ? 115.391 168.716 157.093 1.00 13.41 ? 93  TRP B CE3 1 
ATOM 1126 C CZ2 . TRP B 1 93  ? 114.621 170.776 158.872 1.00 16.24 ? 93  TRP B CZ2 1 
ATOM 1127 C CZ3 . TRP B 1 93  ? 116.318 169.378 157.876 1.00 16.46 ? 93  TRP B CZ3 1 
ATOM 1128 C CH2 . TRP B 1 93  ? 115.929 170.397 158.752 1.00 14.58 ? 93  TRP B CH2 1 
ATOM 1129 N N   . GLY B 1 94  ? 114.858 165.632 156.184 1.00 12.32 ? 94  GLY B N   1 
ATOM 1130 C CA  . GLY B 1 94  ? 116.093 165.183 156.791 1.00 20.82 ? 94  GLY B CA  1 
ATOM 1131 C C   . GLY B 1 94  ? 117.335 165.652 156.062 1.00 1.63  ? 94  GLY B C   1 
ATOM 1132 O O   . GLY B 1 94  ? 117.424 165.545 154.836 1.00 6.23  ? 94  GLY B O   1 
ATOM 1133 N N   . GLN B 1 95  ? 118.303 166.171 156.809 1.00 3.89  ? 95  GLN B N   1 
ATOM 1134 C CA  . GLN B 1 95  ? 119.579 166.608 156.259 1.00 7.12  ? 95  GLN B CA  1 
ATOM 1135 C C   . GLN B 1 95  ? 120.675 165.672 156.744 1.00 14.08 ? 95  GLN B C   1 
ATOM 1136 O O   . GLN B 1 95  ? 120.816 165.447 157.951 1.00 11.67 ? 95  GLN B O   1 
ATOM 1137 C CB  . GLN B 1 95  ? 119.888 168.051 156.667 1.00 20.06 ? 95  GLN B CB  1 
ATOM 1138 C CG  . GLN B 1 95  ? 119.244 169.100 155.775 1.00 12.05 ? 95  GLN B CG  1 
ATOM 1139 C CD  . GLN B 1 95  ? 119.509 170.514 156.254 1.00 13.50 ? 95  GLN B CD  1 
ATOM 1140 O OE1 . GLN B 1 95  ? 119.249 170.848 157.409 1.00 21.18 ? 95  GLN B OE1 1 
ATOM 1141 N NE2 . GLN B 1 95  ? 120.028 171.352 155.365 1.00 9.13  ? 95  GLN B NE2 1 
ATOM 1142 N N   . GLY B 1 96  ? 121.443 165.128 155.804 1.00 19.23 ? 96  GLY B N   1 
ATOM 1143 C CA  . GLY B 1 96  ? 122.484 164.187 156.163 1.00 15.72 ? 96  GLY B CA  1 
ATOM 1144 C C   . GLY B 1 96  ? 123.598 164.841 156.961 1.00 11.39 ? 96  GLY B C   1 
ATOM 1145 O O   . GLY B 1 96  ? 123.888 166.028 156.820 1.00 15.84 ? 96  GLY B O   1 
ATOM 1146 N N   . GLY B 1 97  ? 124.225 164.041 157.819 1.00 26.07 ? 97  GLY B N   1 
ATOM 1147 C CA  . GLY B 1 97  ? 125.313 164.546 158.631 1.00 21.87 ? 97  GLY B CA  1 
ATOM 1148 C C   . GLY B 1 97  ? 126.507 164.958 157.791 1.00 19.44 ? 97  GLY B C   1 
ATOM 1149 O O   . GLY B 1 97  ? 126.822 164.351 156.767 1.00 24.60 ? 97  GLY B O   1 
ATOM 1150 N N   . THR B 1 98  ? 127.182 166.010 158.239 1.00 16.16 ? 98  THR B N   1 
ATOM 1151 C CA  . THR B 1 98  ? 128.318 166.572 157.524 1.00 20.45 ? 98  THR B CA  1 
ATOM 1152 C C   . THR B 1 98  ? 129.612 166.101 158.177 1.00 28.17 ? 98  THR B C   1 
ATOM 1153 O O   . THR B 1 98  ? 129.853 166.376 159.357 1.00 24.95 ? 98  THR B O   1 
ATOM 1154 C CB  . THR B 1 98  ? 128.257 168.098 157.508 1.00 27.73 ? 98  THR B CB  1 
ATOM 1155 O OG1 . THR B 1 98  ? 127.093 168.526 156.791 1.00 34.87 ? 98  THR B OG1 1 
ATOM 1156 C CG2 . THR B 1 98  ? 129.494 168.666 156.835 1.00 25.45 ? 98  THR B CG2 1 
ATOM 1157 N N   . HIS B 1 99  ? 130.435 165.393 157.409 1.00 29.53 ? 99  HIS B N   1 
ATOM 1158 C CA  . HIS B 1 99  ? 131.776 164.989 157.828 1.00 21.77 ? 99  HIS B CA  1 
ATOM 1159 C C   . HIS B 1 99  ? 132.751 165.669 156.876 1.00 18.56 ? 99  HIS B C   1 
ATOM 1160 O O   . HIS B 1 99  ? 133.199 165.078 155.891 1.00 27.14 ? 99  HIS B O   1 
ATOM 1161 C CB  . HIS B 1 99  ? 131.930 163.462 157.816 1.00 23.79 ? 99  HIS B CB  1 
ATOM 1162 C CG  . HIS B 1 99  ? 130.822 162.737 158.516 1.00 31.37 ? 99  HIS B CG  1 
ATOM 1163 N ND1 . HIS B 1 99  ? 129.553 162.630 157.990 1.00 26.06 ? 99  HIS B ND1 1 
ATOM 1164 C CD2 . HIS B 1 99  ? 130.795 162.080 159.699 1.00 33.68 ? 99  HIS B CD2 1 
ATOM 1165 C CE1 . HIS B 1 99  ? 128.791 161.940 158.820 1.00 25.46 ? 99  HIS B CE1 1 
ATOM 1166 N NE2 . HIS B 1 99  ? 129.521 161.595 159.865 1.00 32.69 ? 99  HIS B NE2 1 
ATOM 1167 N N   . SER B 1 100 ? 133.089 166.917 157.184 1.00 24.22 ? 100 SER B N   1 
ATOM 1168 C CA  . SER B 1 100 ? 133.869 167.762 156.292 1.00 20.38 ? 100 SER B CA  1 
ATOM 1169 C C   . SER B 1 100 ? 135.096 168.287 157.018 1.00 22.99 ? 100 SER B C   1 
ATOM 1170 O O   . SER B 1 100 ? 135.031 168.626 158.201 1.00 27.23 ? 100 SER B O   1 
ATOM 1171 C CB  . SER B 1 100 ? 133.029 168.932 155.769 1.00 26.48 ? 100 SER B CB  1 
ATOM 1172 O OG  . SER B 1 100 ? 132.060 168.486 154.836 1.00 26.03 ? 100 SER B OG  1 
ATOM 1173 N N   . GLN B 1 101 ? 136.214 168.356 156.303 1.00 21.79 ? 101 GLN B N   1 
ATOM 1174 C CA  . GLN B 1 101 ? 137.471 168.816 156.875 1.00 20.71 ? 101 GLN B CA  1 
ATOM 1175 C C   . GLN B 1 101 ? 138.040 169.941 156.027 1.00 10.68 ? 101 GLN B C   1 
ATOM 1176 O O   . GLN B 1 101 ? 138.220 169.778 154.818 1.00 30.42 ? 101 GLN B O   1 
ATOM 1177 C CB  . GLN B 1 101 ? 138.485 167.670 156.973 1.00 12.44 ? 101 GLN B CB  1 
ATOM 1178 C CG  . GLN B 1 101 ? 138.119 166.602 157.990 1.00 10.43 ? 101 GLN B CG  1 
ATOM 1179 C CD  . GLN B 1 101 ? 137.170 165.562 157.428 1.00 15.80 ? 101 GLN B CD  1 
ATOM 1180 O OE1 . GLN B 1 101 ? 137.222 165.236 156.242 1.00 20.91 ? 101 GLN B OE1 1 
ATOM 1181 N NE2 . GLN B 1 101 ? 136.297 165.036 158.277 1.00 23.88 ? 101 GLN B NE2 1 
ATOM 1182 N N   . TRP B 1 102 ? 138.328 171.078 156.663 1.00 6.30  ? 102 TRP B N   1 
ATOM 1183 C CA  . TRP B 1 102 ? 138.981 172.166 155.942 1.00 1.57  ? 102 TRP B CA  1 
ATOM 1184 C C   . TRP B 1 102 ? 140.374 171.768 155.476 1.00 18.29 ? 102 TRP B C   1 
ATOM 1185 O O   . TRP B 1 102 ? 140.872 172.302 154.477 1.00 18.74 ? 102 TRP B O   1 
ATOM 1186 C CB  . TRP B 1 102 ? 139.048 173.417 156.817 1.00 12.63 ? 102 TRP B CB  1 
ATOM 1187 C CG  . TRP B 1 102 ? 139.537 174.627 156.081 1.00 14.90 ? 102 TRP B CG  1 
ATOM 1188 C CD1 . TRP B 1 102 ? 140.754 175.228 156.211 1.00 13.41 ? 102 TRP B CD1 1 
ATOM 1189 C CD2 . TRP B 1 102 ? 138.823 175.377 155.093 1.00 11.77 ? 102 TRP B CD2 1 
ATOM 1190 N NE1 . TRP B 1 102 ? 140.840 176.308 155.368 1.00 9.17  ? 102 TRP B NE1 1 
ATOM 1191 C CE2 . TRP B 1 102 ? 139.667 176.421 154.670 1.00 4.61  ? 102 TRP B CE2 1 
ATOM 1192 C CE3 . TRP B 1 102 ? 137.548 175.269 154.527 1.00 14.49 ? 102 TRP B CE3 1 
ATOM 1193 C CZ2 . TRP B 1 102 ? 139.281 177.350 153.707 1.00 8.88  ? 102 TRP B CZ2 1 
ATOM 1194 C CZ3 . TRP B 1 102 ? 137.167 176.192 153.571 1.00 9.74  ? 102 TRP B CZ3 1 
ATOM 1195 C CH2 . TRP B 1 102 ? 138.030 177.218 153.171 1.00 9.87  ? 102 TRP B CH2 1 
ATOM 1196 N N   . ASN B 1 103 ? 141.014 170.838 156.179 1.00 29.15 ? 103 ASN B N   1 
ATOM 1197 C CA  . ASN B 1 103 ? 142.325 170.331 155.786 1.00 19.27 ? 103 ASN B CA  1 
ATOM 1198 C C   . ASN B 1 103 ? 142.464 168.929 156.360 1.00 23.02 ? 103 ASN B C   1 
ATOM 1199 O O   . ASN B 1 103 ? 142.509 168.762 157.582 1.00 20.73 ? 103 ASN B O   1 
ATOM 1200 C CB  . ASN B 1 103 ? 143.442 171.244 156.284 1.00 10.46 ? 103 ASN B CB  1 
ATOM 1201 C CG  . ASN B 1 103 ? 144.793 170.880 155.705 1.00 23.51 ? 103 ASN B CG  1 
ATOM 1202 O OD1 . ASN B 1 103 ? 144.889 170.405 154.574 1.00 13.51 ? 103 ASN B OD1 1 
ATOM 1203 N ND2 . ASN B 1 103 ? 145.848 171.102 156.479 1.00 25.90 ? 103 ASN B ND2 1 
ATOM 1204 N N   . LYS B 1 104 ? 142.530 167.927 155.484 1.00 14.47 ? 104 LYS B N   1 
ATOM 1205 C CA  . LYS B 1 104 ? 142.633 166.525 155.886 1.00 13.11 ? 104 LYS B CA  1 
ATOM 1206 C C   . LYS B 1 104 ? 143.812 165.884 155.168 1.00 21.71 ? 104 LYS B C   1 
ATOM 1207 O O   . LYS B 1 104 ? 143.632 165.127 154.203 1.00 26.40 ? 104 LYS B O   1 
ATOM 1208 C CB  . LYS B 1 104 ? 141.335 165.769 155.594 1.00 11.00 ? 104 LYS B CB  1 
ATOM 1209 C CG  . LYS B 1 104 ? 141.255 164.400 156.247 1.00 14.11 ? 104 LYS B CG  1 
ATOM 1210 C CD  . LYS B 1 104 ? 140.061 163.613 155.737 1.00 14.28 ? 104 LYS B CD  1 
ATOM 1211 C CE  . LYS B 1 104 ? 140.251 162.121 155.952 1.00 20.12 ? 104 LYS B CE  1 
ATOM 1212 N NZ  . LYS B 1 104 ? 140.316 161.770 157.397 1.00 22.75 ? 104 LYS B NZ  1 
ATOM 1213 N N   . PRO B 1 105 ? 145.039 166.168 155.607 1.00 27.36 ? 105 PRO B N   1 
ATOM 1214 C CA  . PRO B 1 105 ? 146.203 165.495 155.021 1.00 24.88 ? 105 PRO B CA  1 
ATOM 1215 C C   . PRO B 1 105 ? 146.525 164.191 155.733 1.00 27.76 ? 105 PRO B C   1 
ATOM 1216 O O   . PRO B 1 105 ? 146.665 164.165 156.959 1.00 24.01 ? 105 PRO B O   1 
ATOM 1217 C CB  . PRO B 1 105 ? 147.327 166.525 155.189 1.00 20.61 ? 105 PRO B CB  1 
ATOM 1218 C CG  . PRO B 1 105 ? 146.864 167.448 156.300 1.00 27.07 ? 105 PRO B CG  1 
ATOM 1219 C CD  . PRO B 1 105 ? 145.432 167.136 156.644 1.00 26.96 ? 105 PRO B CD  1 
ATOM 1220 N N   . SER B 1 106 ? 146.647 163.105 154.977 1.00 27.43 ? 106 SER B N   1 
ATOM 1221 C CA  . SER B 1 106 ? 146.912 161.788 155.538 1.00 26.39 ? 106 SER B CA  1 
ATOM 1222 C C   . SER B 1 106 ? 148.383 161.440 155.360 1.00 37.67 ? 106 SER B C   1 
ATOM 1223 O O   . SER B 1 106 ? 148.900 161.466 154.239 1.00 36.63 ? 106 SER B O   1 
ATOM 1224 C CB  . SER B 1 106 ? 146.033 160.727 154.873 1.00 30.29 ? 106 SER B CB  1 
ATOM 1225 O OG  . SER B 1 106 ? 146.117 159.492 155.564 1.00 39.13 ? 106 SER B OG  1 
ATOM 1226 N N   . LYS B 1 107 ? 149.045 161.113 156.467 1.00 36.62 ? 107 LYS B N   1 
ATOM 1227 C CA  . LYS B 1 107 ? 150.455 160.739 156.481 1.00 32.08 ? 107 LYS B CA  1 
ATOM 1228 C C   . LYS B 1 107 ? 151.354 161.721 155.723 1.00 32.37 ? 107 LYS B C   1 
ATOM 1229 O O   . LYS B 1 107 ? 152.023 161.338 154.757 1.00 34.11 ? 107 LYS B O   1 
ATOM 1230 C CB  . LYS B 1 107 ? 150.634 159.327 155.941 1.00 30.25 ? 107 LYS B CB  1 
ATOM 1231 C CG  . LYS B 1 107 ? 149.875 158.262 156.714 1.00 33.37 ? 107 LYS B CG  1 
ATOM 1232 C CD  . LYS B 1 107 ? 149.740 156.986 155.900 1.00 33.55 ? 107 LYS B CD  1 
ATOM 1233 C CE  . LYS B 1 107 ? 148.842 155.977 156.597 1.00 31.41 ? 107 LYS B CE  1 
ATOM 1234 N NZ  . LYS B 1 107 ? 148.703 154.723 155.806 1.00 34.53 ? 107 LYS B NZ  1 
ATOM 1235 N N   . PRO B 1 108 ? 151.396 162.996 156.133 1.00 30.95 ? 108 PRO B N   1 
ATOM 1236 C CA  . PRO B 1 108 ? 152.319 163.945 155.497 1.00 28.77 ? 108 PRO B CA  1 
ATOM 1237 C C   . PRO B 1 108 ? 153.731 163.798 156.042 1.00 36.78 ? 108 PRO B C   1 
ATOM 1238 O O   . PRO B 1 108 ? 154.034 164.222 157.162 1.00 43.26 ? 108 PRO B O   1 
ATOM 1239 C CB  . PRO B 1 108 ? 151.702 165.307 155.844 1.00 27.38 ? 108 PRO B CB  1 
ATOM 1240 C CG  . PRO B 1 108 ? 151.050 165.089 157.155 1.00 28.40 ? 108 PRO B CG  1 
ATOM 1241 C CD  . PRO B 1 108 ? 150.626 163.634 157.217 1.00 31.51 ? 108 PRO B CD  1 
ATOM 1242 N N   . LYS B 1 109 ? 154.604 163.192 155.242 1.00 33.61 ? 109 LYS B N   1 
ATOM 1243 C CA  . LYS B 1 109 ? 156.012 163.029 155.586 1.00 28.35 ? 109 LYS B CA  1 
ATOM 1244 C C   . LYS B 1 109 ? 156.788 164.135 154.883 1.00 33.90 ? 109 LYS B C   1 
ATOM 1245 O O   . LYS B 1 109 ? 156.910 164.132 153.654 1.00 34.26 ? 109 LYS B O   1 
ATOM 1246 C CB  . LYS B 1 109 ? 156.517 161.647 155.178 1.00 23.60 ? 109 LYS B CB  1 
ATOM 1247 C CG  . LYS B 1 109 ? 155.957 160.513 156.021 1.00 31.99 ? 109 LYS B CG  1 
ATOM 1248 C CD  . LYS B 1 109 ? 156.429 159.160 155.518 1.00 35.40 ? 109 LYS B CD  1 
ATOM 1249 C CE  . LYS B 1 109 ? 155.856 158.030 156.358 1.00 33.48 ? 109 LYS B CE  1 
ATOM 1250 N NZ  . LYS B 1 109 ? 156.305 156.695 155.876 1.00 38.08 ? 109 LYS B NZ  1 
ATOM 1251 N N   . THR B 1 110 ? 157.313 165.077 155.660 1.00 29.95 ? 110 THR B N   1 
ATOM 1252 C CA  . THR B 1 110 ? 157.905 166.282 155.102 1.00 29.13 ? 110 THR B CA  1 
ATOM 1253 C C   . THR B 1 110 ? 159.231 166.578 155.780 1.00 28.75 ? 110 THR B C   1 
ATOM 1254 O O   . THR B 1 110 ? 159.367 166.418 156.997 1.00 36.30 ? 110 THR B O   1 
ATOM 1255 C CB  . THR B 1 110 ? 156.964 167.483 155.260 1.00 31.82 ? 110 THR B CB  1 
ATOM 1256 O OG1 . THR B 1 110 ? 155.640 167.113 154.856 1.00 34.95 ? 110 THR B OG1 1 
ATOM 1257 C CG2 . THR B 1 110 ? 157.438 168.644 154.407 1.00 28.18 ? 110 THR B CG2 1 
ATOM 1258 N N   . ASN B 1 111 ? 160.208 167.006 154.985 1.00 32.50 ? 111 ASN B N   1 
ATOM 1259 C CA  . ASN B 1 111 ? 161.495 167.471 155.483 1.00 35.76 ? 111 ASN B CA  1 
ATOM 1260 C C   . ASN B 1 111 ? 161.742 168.870 154.941 1.00 29.82 ? 111 ASN B C   1 
ATOM 1261 O O   . ASN B 1 111 ? 161.736 169.076 153.723 1.00 29.82 ? 111 ASN B O   1 
ATOM 1262 C CB  . ASN B 1 111 ? 162.622 166.520 155.075 1.00 31.62 ? 111 ASN B CB  1 
ATOM 1263 C CG  . ASN B 1 111 ? 162.521 165.172 155.758 1.00 27.28 ? 111 ASN B CG  1 
ATOM 1264 O OD1 . ASN B 1 111 ? 162.918 165.018 156.913 1.00 29.74 ? 111 ASN B OD1 1 
ATOM 1265 N ND2 . ASN B 1 111 ? 161.988 164.186 155.047 1.00 31.69 ? 111 ASN B ND2 1 
ATOM 1266 N N   . MET B 1 112 ? 161.955 169.825 155.843 1.00 28.87 ? 112 MET B N   1 
ATOM 1267 C CA  . MET B 1 112 ? 162.190 171.210 155.467 1.00 20.10 ? 112 MET B CA  1 
ATOM 1268 C C   . MET B 1 112 ? 163.113 171.837 156.502 1.00 25.20 ? 112 MET B C   1 
ATOM 1269 O O   . MET B 1 112 ? 163.540 171.183 157.456 1.00 30.65 ? 112 MET B O   1 
ATOM 1270 C CB  . MET B 1 112 ? 160.872 171.978 155.341 1.00 22.06 ? 112 MET B CB  1 
ATOM 1271 C CG  . MET B 1 112 ? 159.964 171.847 156.547 1.00 25.37 ? 112 MET B CG  1 
ATOM 1272 S SD  . MET B 1 112 ? 158.289 172.405 156.197 1.00 36.99 ? 112 MET B SD  1 
ATOM 1273 C CE  . MET B 1 112 ? 157.432 171.810 157.648 1.00 25.12 ? 112 MET B CE  1 
ATOM 1274 N N   . LYS B 1 113 ? 163.440 173.112 156.298 1.00 26.64 ? 113 LYS B N   1 
ATOM 1275 C CA  . LYS B 1 113 ? 164.304 173.831 157.227 1.00 29.89 ? 113 LYS B CA  1 
ATOM 1276 C C   . LYS B 1 113 ? 163.587 174.992 157.904 1.00 31.54 ? 113 LYS B C   1 
ATOM 1277 O O   . LYS B 1 113 ? 163.531 175.037 159.136 1.00 37.97 ? 113 LYS B O   1 
ATOM 1278 C CB  . LYS B 1 113 ? 165.565 174.320 156.503 1.00 28.96 ? 113 LYS B CB  1 
ATOM 1279 C CG  . LYS B 1 113 ? 166.669 174.792 157.432 1.00 33.46 ? 113 LYS B CG  1 
ATOM 1280 C CD  . LYS B 1 113 ? 167.876 175.287 156.655 1.00 31.25 ? 113 LYS B CD  1 
ATOM 1281 C CE  . LYS B 1 113 ? 168.884 175.952 157.579 1.00 36.76 ? 113 LYS B CE  1 
ATOM 1282 N NZ  . LYS B 1 113 ? 170.018 176.555 156.825 1.00 38.57 ? 113 LYS B NZ  1 
ATOM 1283 N N   . HIS B 1 114 ? 163.023 175.927 157.143 1.00 33.67 ? 114 HIS B N   1 
ATOM 1284 C CA  . HIS B 1 114 ? 162.444 177.139 157.707 1.00 34.05 ? 114 HIS B CA  1 
ATOM 1285 C C   . HIS B 1 114 ? 161.003 177.297 157.251 1.00 31.66 ? 114 HIS B C   1 
ATOM 1286 O O   . HIS B 1 114 ? 160.710 177.188 156.056 1.00 37.45 ? 114 HIS B O   1 
ATOM 1287 C CB  . HIS B 1 114 ? 163.259 178.373 157.309 1.00 32.62 ? 114 HIS B CB  1 
ATOM 1288 C CG  . HIS B 1 114 ? 164.608 178.439 157.957 1.00 30.52 ? 114 HIS B CG  1 
ATOM 1289 N ND1 . HIS B 1 114 ? 164.977 177.609 158.992 1.00 31.54 ? 114 HIS B ND1 1 
ATOM 1290 C CD2 . HIS B 1 114 ? 165.677 179.234 157.712 1.00 37.57 ? 114 HIS B CD2 1 
ATOM 1291 C CE1 . HIS B 1 114 ? 166.213 177.890 159.360 1.00 32.97 ? 114 HIS B CE1 1 
ATOM 1292 N NE2 . HIS B 1 114 ? 166.662 178.872 158.599 1.00 41.34 ? 114 HIS B NE2 1 
ATOM 1293 N N   . VAL B 1 115 ? 160.112 177.549 158.203 1.00 18.65 ? 115 VAL B N   1 
ATOM 1294 C CA  . VAL B 1 115 ? 158.711 177.860 157.930 1.00 20.95 ? 115 VAL B CA  1 
ATOM 1295 C C   . VAL B 1 115 ? 158.443 179.220 158.560 1.00 29.71 ? 115 VAL B C   1 
ATOM 1296 O O   . VAL B 1 115 ? 158.129 179.317 159.751 1.00 24.09 ? 115 VAL B O   1 
ATOM 1297 C CB  . VAL B 1 115 ? 157.756 176.794 158.477 1.00 22.37 ? 115 VAL B CB  1 
ATOM 1298 C CG1 . VAL B 1 115 ? 156.347 177.029 157.955 1.00 20.55 ? 115 VAL B CG1 1 
ATOM 1299 C CG2 . VAL B 1 115 ? 158.243 175.405 158.107 1.00 21.59 ? 115 VAL B CG2 1 
ATOM 1300 N N   . ALA B 1 116 ? 158.568 180.281 157.766 1.00 28.27 ? 116 ALA B N   1 
ATOM 1301 C CA  . ALA B 1 116 ? 158.400 181.647 158.245 1.00 19.56 ? 116 ALA B CA  1 
ATOM 1302 C C   . ALA B 1 116 ? 157.182 182.266 157.577 1.00 22.30 ? 116 ALA B C   1 
ATOM 1303 O O   . ALA B 1 116 ? 157.139 182.384 156.348 1.00 21.11 ? 116 ALA B O   1 
ATOM 1304 C CB  . ALA B 1 116 ? 159.648 182.485 157.964 1.00 24.56 ? 116 ALA B CB  1 
ATOM 1305 N N   . GLY B 1 117 ? 156.200 182.655 158.383 1.00 23.46 ? 117 GLY B N   1 
ATOM 1306 C CA  . GLY B 1 117 ? 155.019 183.328 157.865 1.00 22.14 ? 117 GLY B CA  1 
ATOM 1307 C C   . GLY B 1 117 ? 154.251 182.522 156.841 1.00 15.74 ? 117 GLY B C   1 
ATOM 1308 O O   . GLY B 1 117 ? 153.697 183.095 155.894 1.00 20.89 ? 117 GLY B O   1 
ATOM 1309 N N   . ALA B 1 118 ? 154.183 181.207 157.020 1.00 16.73 ? 118 ALA B N   1 
ATOM 1310 C CA  . ALA B 1 118 ? 153.639 180.320 156.003 1.00 17.08 ? 118 ALA B CA  1 
ATOM 1311 C C   . ALA B 1 118 ? 152.852 179.209 156.686 1.00 12.57 ? 118 ALA B C   1 
ATOM 1312 O O   . ALA B 1 118 ? 152.560 179.267 157.884 1.00 17.19 ? 118 ALA B O   1 
ATOM 1313 C CB  . ALA B 1 118 ? 154.764 179.771 155.117 1.00 19.48 ? 118 ALA B CB  1 
ATOM 1314 N N   . ALA B 1 119 ? 152.492 178.193 155.906 1.00 15.85 ? 119 ALA B N   1 
ATOM 1315 C CA  . ALA B 1 119 ? 151.829 177.004 156.414 1.00 21.52 ? 119 ALA B CA  1 
ATOM 1316 C C   . ALA B 1 119 ? 152.478 175.781 155.786 1.00 22.91 ? 119 ALA B C   1 
ATOM 1317 O O   . ALA B 1 119 ? 152.786 175.782 154.591 1.00 25.54 ? 119 ALA B O   1 
ATOM 1318 C CB  . ALA B 1 119 ? 150.327 177.019 156.112 1.00 26.27 ? 119 ALA B CB  1 
ATOM 1319 N N   . ALA B 1 120 ? 152.681 174.743 156.591 1.00 24.69 ? 120 ALA B N   1 
ATOM 1320 C CA  . ALA B 1 120 ? 153.351 173.547 156.106 1.00 22.52 ? 120 ALA B CA  1 
ATOM 1321 C C   . ALA B 1 120 ? 152.962 172.364 156.979 1.00 20.24 ? 120 ALA B C   1 
ATOM 1322 O O   . ALA B 1 120 ? 152.423 172.529 158.077 1.00 15.88 ? 120 ALA B O   1 
ATOM 1323 C CB  . ALA B 1 120 ? 154.871 173.729 156.083 1.00 22.31 ? 120 ALA B CB  1 
ATOM 1324 N N   . ALA B 1 121 ? 153.244 171.165 156.466 1.00 26.64 ? 121 ALA B N   1 
ATOM 1325 C CA  . ALA B 1 121 ? 152.976 169.910 157.169 1.00 20.64 ? 121 ALA B CA  1 
ATOM 1326 C C   . ALA B 1 121 ? 151.511 169.800 157.588 1.00 14.52 ? 121 ALA B C   1 
ATOM 1327 O O   . ALA B 1 121 ? 151.196 169.381 158.703 1.00 24.01 ? 121 ALA B O   1 
ATOM 1328 C CB  . ALA B 1 121 ? 153.904 169.742 158.374 1.00 21.13 ? 121 ALA B CB  1 
ATOM 1329 N N   . GLY B 1 122 ? 150.611 170.178 156.685 1.00 16.58 ? 122 GLY B N   1 
ATOM 1330 C CA  . GLY B 1 122 ? 149.188 170.056 156.928 1.00 17.78 ? 122 GLY B CA  1 
ATOM 1331 C C   . GLY B 1 122 ? 148.663 170.917 158.058 1.00 27.05 ? 122 GLY B C   1 
ATOM 1332 O O   . GLY B 1 122 ? 147.894 170.444 158.901 1.00 25.18 ? 122 GLY B O   1 
ATOM 1333 N N   . ALA B 1 123 ? 149.063 172.185 158.082 1.00 29.98 ? 123 ALA B N   1 
ATOM 1334 C CA  . ALA B 1 123 ? 148.672 173.119 159.126 1.00 17.91 ? 123 ALA B CA  1 
ATOM 1335 C C   . ALA B 1 123 ? 147.854 174.254 158.527 1.00 23.11 ? 123 ALA B C   1 
ATOM 1336 O O   . ALA B 1 123 ? 148.125 174.707 157.411 1.00 27.15 ? 123 ALA B O   1 
ATOM 1337 C CB  . ALA B 1 123 ? 149.900 173.677 159.843 1.00 14.96 ? 123 ALA B CB  1 
ATOM 1338 N N   . VAL B 1 124 ? 146.852 174.716 159.273 1.00 22.29 ? 124 VAL B N   1 
ATOM 1339 C CA  . VAL B 1 124 ? 145.952 175.774 158.828 1.00 22.66 ? 124 VAL B CA  1 
ATOM 1340 C C   . VAL B 1 124 ? 146.265 177.042 159.610 1.00 21.01 ? 124 VAL B C   1 
ATOM 1341 O O   . VAL B 1 124 ? 146.270 177.029 160.845 1.00 29.05 ? 124 VAL B O   1 
ATOM 1342 C CB  . VAL B 1 124 ? 144.477 175.375 159.003 1.00 12.52 ? 124 VAL B CB  1 
ATOM 1343 C CG1 . VAL B 1 124 ? 143.588 176.264 158.153 1.00 22.96 ? 124 VAL B CG1 1 
ATOM 1344 C CG2 . VAL B 1 124 ? 144.281 173.916 158.638 1.00 21.31 ? 124 VAL B CG2 1 
ATOM 1345 N N   . VAL B 1 125 ? 146.527 178.131 158.895 1.00 23.70 ? 125 VAL B N   1 
ATOM 1346 C CA  . VAL B 1 125 ? 146.821 179.422 159.545 1.00 23.30 ? 125 VAL B CA  1 
ATOM 1347 C C   . VAL B 1 125 ? 145.488 180.147 159.686 1.00 25.73 ? 125 VAL B C   1 
ATOM 1348 O O   . VAL B 1 125 ? 145.108 181.002 158.882 1.00 20.16 ? 125 VAL B O   1 
ATOM 1349 C CB  . VAL B 1 125 ? 147.859 180.239 158.773 1.00 15.60 ? 125 VAL B CB  1 
ATOM 1350 C CG1 . VAL B 1 125 ? 148.252 181.474 159.566 1.00 18.99 ? 125 VAL B CG1 1 
ATOM 1351 C CG2 . VAL B 1 125 ? 149.078 179.392 158.471 1.00 19.98 ? 125 VAL B CG2 1 
ATOM 1352 N N   . GLY B 1 126 ? 144.765 179.813 160.749 1.00 32.52 ? 126 GLY B N   1 
ATOM 1353 C CA  . GLY B 1 126 ? 143.613 180.598 161.145 1.00 31.95 ? 126 GLY B CA  1 
ATOM 1354 C C   . GLY B 1 126 ? 142.297 180.294 160.461 1.00 27.90 ? 126 GLY B C   1 
ATOM 1355 O O   . GLY B 1 126 ? 142.200 180.307 159.231 1.00 20.23 ? 126 GLY B O   1 
ATOM 1356 N N   . GLY B 1 127 ? 141.270 180.026 161.264 1.00 34.95 ? 127 GLY B N   1 
ATOM 1357 C CA  . GLY B 1 127 ? 139.901 180.014 160.790 1.00 24.24 ? 127 GLY B CA  1 
ATOM 1358 C C   . GLY B 1 127 ? 139.174 181.232 161.320 1.00 23.88 ? 127 GLY B C   1 
ATOM 1359 O O   . GLY B 1 127 ? 138.886 181.307 162.518 1.00 26.23 ? 127 GLY B O   1 
ATOM 1360 N N   . LEU B 1 128 ? 138.880 182.190 160.439 1.00 28.08 ? 128 LEU B N   1 
ATOM 1361 C CA  . LEU B 1 128 ? 138.448 183.529 160.846 1.00 27.75 ? 128 LEU B CA  1 
ATOM 1362 C C   . LEU B 1 128 ? 139.464 184.163 161.790 1.00 20.50 ? 128 LEU B C   1 
ATOM 1363 O O   . LEU B 1 128 ? 139.108 184.852 162.748 1.00 30.31 ? 128 LEU B O   1 
ATOM 1364 C CB  . LEU B 1 128 ? 137.055 183.512 161.477 1.00 24.56 ? 128 LEU B CB  1 
ATOM 1365 C CG  . LEU B 1 128 ? 135.871 183.374 160.526 1.00 31.30 ? 128 LEU B CG  1 
ATOM 1366 C CD1 . LEU B 1 128 ? 134.594 183.091 161.290 1.00 26.36 ? 128 LEU B CD1 1 
ATOM 1367 C CD2 . LEU B 1 128 ? 135.731 184.644 159.719 1.00 31.54 ? 128 LEU B CD2 1 
ATOM 1368 N N   . GLY B 1 129 ? 140.743 183.934 161.509 1.00 18.68 ? 129 GLY B N   1 
ATOM 1369 C CA  . GLY B 1 129 ? 141.811 184.438 162.347 1.00 20.43 ? 129 GLY B CA  1 
ATOM 1370 C C   . GLY B 1 129 ? 143.179 184.193 161.748 1.00 18.98 ? 129 GLY B C   1 
ATOM 1371 O O   . GLY B 1 129 ? 143.325 184.124 160.524 1.00 27.51 ? 129 GLY B O   1 
ATOM 1372 N N   . GLY B 1 130 ? 144.188 184.058 162.602 1.00 18.01 ? 130 GLY B N   1 
ATOM 1373 C CA  . GLY B 1 130 ? 145.544 183.857 162.138 1.00 18.72 ? 130 GLY B CA  1 
ATOM 1374 C C   . GLY B 1 130 ? 146.471 184.955 162.608 1.00 22.00 ? 130 GLY B C   1 
ATOM 1375 O O   . GLY B 1 130 ? 146.718 185.096 163.809 1.00 23.80 ? 130 GLY B O   1 
ATOM 1376 N N   . TYR B 1 131 ? 146.989 185.742 161.671 1.00 36.73 ? 131 TYR B N   1 
ATOM 1377 C CA  . TYR B 1 131 ? 147.842 186.886 161.979 1.00 37.70 ? 131 TYR B CA  1 
ATOM 1378 C C   . TYR B 1 131 ? 147.107 188.126 161.483 1.00 35.99 ? 131 TYR B C   1 
ATOM 1379 O O   . TYR B 1 131 ? 147.322 188.589 160.360 1.00 30.29 ? 131 TYR B O   1 
ATOM 1380 C CB  . TYR B 1 131 ? 149.223 186.731 161.346 1.00 31.46 ? 131 TYR B CB  1 
ATOM 1381 C CG  . TYR B 1 131 ? 150.051 185.659 162.016 1.00 33.10 ? 131 TYR B CG  1 
ATOM 1382 C CD1 . TYR B 1 131 ? 149.811 184.315 161.764 1.00 33.66 ? 131 TYR B CD1 1 
ATOM 1383 C CD2 . TYR B 1 131 ? 151.054 185.988 162.918 1.00 34.31 ? 131 TYR B CD2 1 
ATOM 1384 C CE1 . TYR B 1 131 ? 150.555 183.329 162.378 1.00 29.12 ? 131 TYR B CE1 1 
ATOM 1385 C CE2 . TYR B 1 131 ? 151.804 185.007 163.539 1.00 35.75 ? 131 TYR B CE2 1 
ATOM 1386 C CZ  . TYR B 1 131 ? 151.548 183.679 163.265 1.00 36.00 ? 131 TYR B CZ  1 
ATOM 1387 O OH  . TYR B 1 131 ? 152.286 182.695 163.879 1.00 36.25 ? 131 TYR B OH  1 
ATOM 1388 N N   . MET B 1 132 ? 146.235 188.659 162.334 1.00 41.84 ? 132 MET B N   1 
ATOM 1389 C CA  . MET B 1 132 ? 145.355 189.774 161.995 1.00 40.74 ? 132 MET B CA  1 
ATOM 1390 C C   . MET B 1 132 ? 145.587 190.873 163.027 1.00 36.12 ? 132 MET B C   1 
ATOM 1391 O O   . MET B 1 132 ? 144.859 190.973 164.016 1.00 39.09 ? 132 MET B O   1 
ATOM 1392 C CB  . MET B 1 132 ? 143.898 189.314 161.968 1.00 38.98 ? 132 MET B CB  1 
ATOM 1393 C CG  . MET B 1 132 ? 143.582 188.348 160.836 1.00 34.61 ? 132 MET B CG  1 
ATOM 1394 S SD  . MET B 1 132 ? 141.888 187.735 160.867 1.00 52.81 ? 132 MET B SD  1 
ATOM 1395 C CE  . MET B 1 132 ? 140.987 189.194 160.363 1.00 46.16 ? 132 MET B CE  1 
ATOM 1396 N N   . LEU B 1 133 ? 146.597 191.711 162.776 1.00 34.63 ? 133 LEU B N   1 
ATOM 1397 C CA  . LEU B 1 133 ? 147.013 192.704 163.762 1.00 32.27 ? 133 LEU B CA  1 
ATOM 1398 C C   . LEU B 1 133 ? 145.881 193.672 164.088 1.00 37.58 ? 133 LEU B C   1 
ATOM 1399 O O   . LEU B 1 133 ? 145.541 193.874 165.259 1.00 43.85 ? 133 LEU B O   1 
ATOM 1400 C CB  . LEU B 1 133 ? 148.245 193.452 163.248 1.00 37.63 ? 133 LEU B CB  1 
ATOM 1401 C CG  . LEU B 1 133 ? 148.971 194.406 164.195 1.00 38.15 ? 133 LEU B CG  1 
ATOM 1402 C CD1 . LEU B 1 133 ? 150.456 194.419 163.888 1.00 40.68 ? 133 LEU B CD1 1 
ATOM 1403 C CD2 . LEU B 1 133 ? 148.401 195.806 164.063 1.00 41.94 ? 133 LEU B CD2 1 
ATOM 1404 N N   . GLY B 1 134 ? 145.289 194.280 163.066 1.00 45.07 ? 134 GLY B N   1 
ATOM 1405 C CA  . GLY B 1 134 ? 144.171 195.177 163.277 1.00 39.06 ? 134 GLY B CA  1 
ATOM 1406 C C   . GLY B 1 134 ? 142.901 194.661 162.637 1.00 43.64 ? 134 GLY B C   1 
ATOM 1407 O O   . GLY B 1 134 ? 142.784 194.642 161.409 1.00 54.53 ? 134 GLY B O   1 
ATOM 1408 N N   . SER B 1 135 ? 141.940 194.241 163.454 1.00 27.65 ? 135 SER B N   1 
ATOM 1409 C CA  . SER B 1 135 ? 140.715 193.649 162.942 1.00 34.47 ? 135 SER B CA  1 
ATOM 1410 C C   . SER B 1 135 ? 139.524 194.149 163.745 1.00 36.67 ? 135 SER B C   1 
ATOM 1411 O O   . SER B 1 135 ? 139.649 194.557 164.902 1.00 42.71 ? 135 SER B O   1 
ATOM 1412 C CB  . SER B 1 135 ? 140.770 192.117 162.981 1.00 36.98 ? 135 SER B CB  1 
ATOM 1413 O OG  . SER B 1 135 ? 139.733 191.552 162.199 1.00 39.23 ? 135 SER B OG  1 
ATOM 1414 N N   . ALA B 1 136 ? 138.359 194.114 163.102 1.00 30.93 ? 136 ALA B N   1 
ATOM 1415 C CA  . ALA B 1 136 ? 137.103 194.482 163.749 1.00 36.52 ? 136 ALA B CA  1 
ATOM 1416 C C   . ALA B 1 136 ? 135.997 193.695 163.063 1.00 37.11 ? 136 ALA B C   1 
ATOM 1417 O O   . ALA B 1 136 ? 135.640 193.996 161.920 1.00 46.08 ? 136 ALA B O   1 
ATOM 1418 C CB  . ALA B 1 136 ? 136.851 195.984 163.661 1.00 35.70 ? 136 ALA B CB  1 
ATOM 1419 N N   . MET B 1 137 ? 135.464 192.687 163.749 1.00 21.54 ? 137 MET B N   1 
ATOM 1420 C CA  . MET B 1 137 ? 134.453 191.805 163.186 1.00 27.00 ? 137 MET B CA  1 
ATOM 1421 C C   . MET B 1 137 ? 133.194 191.859 164.038 1.00 28.23 ? 137 MET B C   1 
ATOM 1422 O O   . MET B 1 137 ? 133.249 191.624 165.248 1.00 31.94 ? 137 MET B O   1 
ATOM 1423 C CB  . MET B 1 137 ? 134.974 190.369 163.090 1.00 34.69 ? 137 MET B CB  1 
ATOM 1424 C CG  . MET B 1 137 ? 136.271 190.240 162.310 1.00 36.57 ? 137 MET B CG  1 
ATOM 1425 S SD  . MET B 1 137 ? 137.234 188.789 162.778 1.00 51.85 ? 137 MET B SD  1 
ATOM 1426 C CE  . MET B 1 137 ? 136.198 187.479 162.135 1.00 38.49 ? 137 MET B CE  1 
ATOM 1427 N N   . SER B 1 138 ? 132.065 192.156 163.404 1.00 30.76 ? 138 SER B N   1 
ATOM 1428 C CA  . SER B 1 138 ? 130.781 192.232 164.088 1.00 23.74 ? 138 SER B CA  1 
ATOM 1429 C C   . SER B 1 138 ? 130.036 190.915 163.918 1.00 26.88 ? 138 SER B C   1 
ATOM 1430 O O   . SER B 1 138 ? 129.888 190.422 162.795 1.00 34.27 ? 138 SER B O   1 
ATOM 1431 C CB  . SER B 1 138 ? 129.940 193.390 163.548 1.00 21.06 ? 138 SER B CB  1 
ATOM 1432 O OG  . SER B 1 138 ? 129.595 193.182 162.191 1.00 34.67 ? 138 SER B OG  1 
ATOM 1433 N N   . ARG B 1 139 ? 129.569 190.361 165.032 1.00 23.95 ? 139 ARG B N   1 
ATOM 1434 C CA  . ARG B 1 139 ? 128.878 189.076 165.061 1.00 24.93 ? 139 ARG B CA  1 
ATOM 1435 C C   . ARG B 1 139 ? 129.646 187.970 164.330 1.00 25.46 ? 139 ARG B C   1 
ATOM 1436 O O   . ARG B 1 139 ? 129.138 187.388 163.366 1.00 24.13 ? 139 ARG B O   1 
ATOM 1437 C CB  . ARG B 1 139 ? 127.470 189.214 164.499 1.00 27.75 ? 139 ARG B CB  1 
ATOM 1438 C CG  . ARG B 1 139 ? 126.512 188.123 164.952 1.00 23.96 ? 139 ARG B CG  1 
ATOM 1439 C CD  . ARG B 1 139 ? 125.194 188.706 165.424 1.00 27.63 ? 139 ARG B CD  1 
ATOM 1440 N NE  . ARG B 1 139 ? 124.297 189.007 164.316 1.00 38.05 ? 139 ARG B NE  1 
ATOM 1441 C CZ  . ARG B 1 139 ? 123.394 188.165 163.833 1.00 36.72 ? 139 ARG B CZ  1 
ATOM 1442 N NH1 . ARG B 1 139 ? 123.247 186.949 164.333 1.00 34.68 ? 139 ARG B NH1 1 
ATOM 1443 N NH2 . ARG B 1 139 ? 122.617 188.552 162.825 1.00 24.54 ? 139 ARG B NH2 1 
ATOM 1444 N N   . PRO B 1 140 ? 130.877 187.657 164.760 1.00 30.70 ? 140 PRO B N   1 
ATOM 1445 C CA  . PRO B 1 140 ? 131.591 186.527 164.154 1.00 18.23 ? 140 PRO B CA  1 
ATOM 1446 C C   . PRO B 1 140 ? 131.206 185.212 164.809 1.00 16.25 ? 140 PRO B C   1 
ATOM 1447 O O   . PRO B 1 140 ? 131.402 185.033 166.014 1.00 19.67 ? 140 PRO B O   1 
ATOM 1448 C CB  . PRO B 1 140 ? 133.069 186.872 164.391 1.00 16.75 ? 140 PRO B CB  1 
ATOM 1449 C CG  . PRO B 1 140 ? 133.080 188.112 165.278 1.00 23.33 ? 140 PRO B CG  1 
ATOM 1450 C CD  . PRO B 1 140 ? 131.694 188.309 165.794 1.00 25.51 ? 140 PRO B CD  1 
ATOM 1451 N N   . LEU B 1 141 ? 130.660 184.283 164.027 1.00 17.64 ? 141 LEU B N   1 
ATOM 1452 C CA  . LEU B 1 141 ? 130.082 183.059 164.564 1.00 12.64 ? 141 LEU B CA  1 
ATOM 1453 C C   . LEU B 1 141 ? 130.710 181.843 163.897 1.00 15.71 ? 141 LEU B C   1 
ATOM 1454 O O   . LEU B 1 141 ? 130.798 181.779 162.668 1.00 15.27 ? 141 LEU B O   1 
ATOM 1455 C CB  . LEU B 1 141 ? 128.562 183.049 164.368 1.00 21.43 ? 141 LEU B CB  1 
ATOM 1456 C CG  . LEU B 1 141 ? 127.821 181.719 164.506 1.00 18.81 ? 141 LEU B CG  1 
ATOM 1457 C CD1 . LEU B 1 141 ? 128.059 181.095 165.865 1.00 16.87 ? 141 LEU B CD1 1 
ATOM 1458 C CD2 . LEU B 1 141 ? 126.333 181.912 164.257 1.00 22.15 ? 141 LEU B CD2 1 
ATOM 1459 N N   . ILE B 1 142 ? 131.144 180.887 164.716 1.00 21.87 ? 142 ILE B N   1 
ATOM 1460 C CA  . ILE B 1 142 ? 131.626 179.590 164.257 1.00 10.68 ? 142 ILE B CA  1 
ATOM 1461 C C   . ILE B 1 142 ? 130.897 178.517 165.052 1.00 15.07 ? 142 ILE B C   1 
ATOM 1462 O O   . ILE B 1 142 ? 131.033 178.456 166.279 1.00 28.23 ? 142 ILE B O   1 
ATOM 1463 C CB  . ILE B 1 142 ? 133.146 179.435 164.432 1.00 19.51 ? 142 ILE B CB  1 
ATOM 1464 C CG1 . ILE B 1 142 ? 133.897 180.472 163.599 1.00 30.02 ? 142 ILE B CG1 1 
ATOM 1465 C CG2 . ILE B 1 142 ? 133.586 178.027 164.061 1.00 16.66 ? 142 ILE B CG2 1 
ATOM 1466 C CD1 . ILE B 1 142 ? 135.399 180.282 163.601 1.00 17.00 ? 142 ILE B CD1 1 
ATOM 1467 N N   . HIS B 1 143 ? 130.132 177.670 164.366 1.00 11.23 ? 143 HIS B N   1 
ATOM 1468 C CA  . HIS B 1 143 ? 129.448 176.567 165.038 1.00 19.18 ? 143 HIS B CA  1 
ATOM 1469 C C   . HIS B 1 143 ? 129.452 175.338 164.142 1.00 17.52 ? 143 HIS B C   1 
ATOM 1470 O O   . HIS B 1 143 ? 128.799 175.321 163.096 1.00 24.83 ? 143 HIS B O   1 
ATOM 1471 C CB  . HIS B 1 143 ? 128.024 176.955 165.451 1.00 14.31 ? 143 HIS B CB  1 
ATOM 1472 C CG  . HIS B 1 143 ? 127.120 177.333 164.318 1.00 11.13 ? 143 HIS B CG  1 
ATOM 1473 N ND1 . HIS B 1 143 ? 127.130 178.585 163.742 1.00 28.99 ? 143 HIS B ND1 1 
ATOM 1474 C CD2 . HIS B 1 143 ? 126.144 176.637 163.689 1.00 18.83 ? 143 HIS B CD2 1 
ATOM 1475 C CE1 . HIS B 1 143 ? 126.212 178.636 162.793 1.00 19.62 ? 143 HIS B CE1 1 
ATOM 1476 N NE2 . HIS B 1 143 ? 125.602 177.467 162.739 1.00 29.50 ? 143 HIS B NE2 1 
ATOM 1477 N N   . PHE B 1 144 ? 130.181 174.303 164.559 1.00 14.58 ? 144 PHE B N   1 
ATOM 1478 C CA  . PHE B 1 144 ? 130.228 173.073 163.781 1.00 14.97 ? 144 PHE B CA  1 
ATOM 1479 C C   . PHE B 1 144 ? 128.905 172.322 163.804 1.00 7.79  ? 144 PHE B C   1 
ATOM 1480 O O   . PHE B 1 144 ? 128.635 171.542 162.886 1.00 34.64 ? 144 PHE B O   1 
ATOM 1481 C CB  . PHE B 1 144 ? 131.353 172.174 164.294 1.00 18.95 ? 144 PHE B CB  1 
ATOM 1482 C CG  . PHE B 1 144 ? 132.715 172.570 163.800 1.00 14.78 ? 144 PHE B CG  1 
ATOM 1483 C CD1 . PHE B 1 144 ? 133.340 173.705 164.289 1.00 13.58 ? 144 PHE B CD1 1 
ATOM 1484 C CD2 . PHE B 1 144 ? 133.367 171.810 162.844 1.00 15.27 ? 144 PHE B CD2 1 
ATOM 1485 C CE1 . PHE B 1 144 ? 134.591 174.072 163.837 1.00 17.23 ? 144 PHE B CE1 1 
ATOM 1486 C CE2 . PHE B 1 144 ? 134.620 172.174 162.388 1.00 15.09 ? 144 PHE B CE2 1 
ATOM 1487 C CZ  . PHE B 1 144 ? 135.232 173.307 162.884 1.00 15.67 ? 144 PHE B CZ  1 
ATOM 1488 N N   . GLY B 1 145 ? 128.072 172.545 164.814 1.00 0.00  ? 145 GLY B N   1 
ATOM 1489 C CA  . GLY B 1 145 ? 126.811 171.843 164.910 1.00 9.34  ? 145 GLY B CA  1 
ATOM 1490 C C   . GLY B 1 145 ? 125.791 172.334 163.899 1.00 16.15 ? 145 GLY B C   1 
ATOM 1491 O O   . GLY B 1 145 ? 125.966 173.342 163.214 1.00 9.66  ? 145 GLY B O   1 
ATOM 1492 N N   . ASN B 1 146 ? 124.696 171.583 163.806 1.00 20.42 ? 146 ASN B N   1 
ATOM 1493 C CA  . ASN B 1 146 ? 123.614 171.935 162.900 1.00 21.22 ? 146 ASN B CA  1 
ATOM 1494 C C   . ASN B 1 146 ? 122.933 173.223 163.347 1.00 19.80 ? 146 ASN B C   1 
ATOM 1495 O O   . ASN B 1 146 ? 122.826 173.516 164.541 1.00 22.01 ? 146 ASN B O   1 
ATOM 1496 C CB  . ASN B 1 146 ? 122.591 170.802 162.823 1.00 20.35 ? 146 ASN B CB  1 
ATOM 1497 C CG  . ASN B 1 146 ? 123.187 169.513 162.298 1.00 25.80 ? 146 ASN B CG  1 
ATOM 1498 O OD1 . ASN B 1 146 ? 123.191 169.262 161.093 1.00 25.52 ? 146 ASN B OD1 1 
ATOM 1499 N ND2 . ASN B 1 146 ? 123.695 168.684 163.203 1.00 23.77 ? 146 ASN B ND2 1 
ATOM 1500 N N   . ASP B 1 147 ? 122.468 173.996 162.370 1.00 24.50 ? 147 ASP B N   1 
ATOM 1501 C CA  . ASP B 1 147 ? 121.827 175.281 162.616 1.00 22.90 ? 147 ASP B CA  1 
ATOM 1502 C C   . ASP B 1 147 ? 120.382 175.230 162.143 1.00 18.37 ? 147 ASP B C   1 
ATOM 1503 O O   . ASP B 1 147 ? 120.106 174.801 161.018 1.00 31.21 ? 147 ASP B O   1 
ATOM 1504 C CB  . ASP B 1 147 ? 122.574 176.412 161.906 1.00 21.68 ? 147 ASP B CB  1 
ATOM 1505 C CG  . ASP B 1 147 ? 122.234 177.777 162.469 1.00 30.17 ? 147 ASP B CG  1 
ATOM 1506 O OD1 . ASP B 1 147 ? 121.594 177.837 163.538 1.00 29.97 ? 147 ASP B OD1 1 
ATOM 1507 O OD2 . ASP B 1 147 ? 122.606 178.790 161.841 1.00 38.96 ? 147 ASP B OD2 1 
ATOM 1508 N N   . TYR B 1 148 ? 119.467 175.666 163.006 1.00 19.69 ? 148 TYR B N   1 
ATOM 1509 C CA  . TYR B 1 148 ? 118.055 175.782 162.671 1.00 22.88 ? 148 TYR B CA  1 
ATOM 1510 C C   . TYR B 1 148 ? 117.581 177.177 163.045 1.00 26.71 ? 148 TYR B C   1 
ATOM 1511 O O   . TYR B 1 148 ? 117.832 177.642 164.161 1.00 23.19 ? 148 TYR B O   1 
ATOM 1512 C CB  . TYR B 1 148 ? 117.220 174.722 163.397 1.00 16.87 ? 148 TYR B CB  1 
ATOM 1513 C CG  . TYR B 1 148 ? 115.766 174.681 162.980 1.00 15.05 ? 148 TYR B CG  1 
ATOM 1514 C CD1 . TYR B 1 148 ? 114.830 175.527 163.562 1.00 19.73 ? 148 TYR B CD1 1 
ATOM 1515 C CD2 . TYR B 1 148 ? 115.328 173.796 162.005 1.00 19.74 ? 148 TYR B CD2 1 
ATOM 1516 C CE1 . TYR B 1 148 ? 113.502 175.491 163.187 1.00 22.95 ? 148 TYR B CE1 1 
ATOM 1517 C CE2 . TYR B 1 148 ? 114.001 173.750 161.624 1.00 17.95 ? 148 TYR B CE2 1 
ATOM 1518 C CZ  . TYR B 1 148 ? 113.093 174.602 162.217 1.00 19.49 ? 148 TYR B CZ  1 
ATOM 1519 O OH  . TYR B 1 148 ? 111.771 174.562 161.839 1.00 24.05 ? 148 TYR B OH  1 
ATOM 1520 N N   . GLU B 1 149 ? 116.899 177.840 162.114 1.00 31.72 ? 149 GLU B N   1 
ATOM 1521 C CA  . GLU B 1 149 ? 116.388 179.187 162.329 1.00 26.09 ? 149 GLU B CA  1 
ATOM 1522 C C   . GLU B 1 149 ? 114.952 179.267 161.839 1.00 25.67 ? 149 GLU B C   1 
ATOM 1523 O O   . GLU B 1 149 ? 114.668 178.937 160.683 1.00 34.57 ? 149 GLU B O   1 
ATOM 1524 C CB  . GLU B 1 149 ? 117.252 180.230 161.612 1.00 31.89 ? 149 GLU B CB  1 
ATOM 1525 C CG  . GLU B 1 149 ? 118.619 180.442 162.240 1.00 36.78 ? 149 GLU B CG  1 
ATOM 1526 C CD  . GLU B 1 149 ? 119.395 181.566 161.582 1.00 43.02 ? 149 GLU B CD  1 
ATOM 1527 O OE1 . GLU B 1 149 ? 118.802 182.301 160.765 1.00 35.95 ? 149 GLU B OE1 1 
ATOM 1528 O OE2 . GLU B 1 149 ? 120.597 181.715 161.882 1.00 47.50 ? 149 GLU B OE2 1 
ATOM 1529 N N   . ASP B 1 150 ? 114.053 179.705 162.719 1.00 33.18 ? 150 ASP B N   1 
ATOM 1530 C CA  . ASP B 1 150 ? 112.645 179.933 162.390 1.00 28.31 ? 150 ASP B CA  1 
ATOM 1531 C C   . ASP B 1 150 ? 112.334 181.372 162.793 1.00 30.42 ? 150 ASP B C   1 
ATOM 1532 O O   . ASP B 1 150 ? 111.889 181.630 163.914 1.00 32.11 ? 150 ASP B O   1 
ATOM 1533 C CB  . ASP B 1 150 ? 111.739 178.930 163.096 1.00 29.78 ? 150 ASP B CB  1 
ATOM 1534 C CG  . ASP B 1 150 ? 110.321 178.951 162.562 1.00 33.97 ? 150 ASP B CG  1 
ATOM 1535 O OD1 . ASP B 1 150 ? 110.086 179.594 161.518 1.00 38.41 ? 150 ASP B OD1 1 
ATOM 1536 O OD2 . ASP B 1 150 ? 109.440 178.323 163.187 1.00 38.20 ? 150 ASP B OD2 1 
ATOM 1537 N N   . ARG B 1 151 ? 112.569 182.303 161.874 1.00 35.19 ? 151 ARG B N   1 
ATOM 1538 C CA  . ARG B 1 151 ? 112.471 183.729 162.156 1.00 27.97 ? 151 ARG B CA  1 
ATOM 1539 C C   . ARG B 1 151 ? 111.158 184.285 161.621 1.00 21.74 ? 151 ARG B C   1 
ATOM 1540 O O   . ARG B 1 151 ? 110.777 184.005 160.480 1.00 20.50 ? 151 ARG B O   1 
ATOM 1541 C CB  . ARG B 1 151 ? 113.649 184.485 161.540 1.00 22.91 ? 151 ARG B CB  1 
ATOM 1542 C CG  . ARG B 1 151 ? 114.965 184.284 162.267 1.00 23.72 ? 151 ARG B CG  1 
ATOM 1543 C CD  . ARG B 1 151 ? 116.040 185.206 161.718 1.00 24.37 ? 151 ARG B CD  1 
ATOM 1544 N NE  . ARG B 1 151 ? 117.230 185.221 162.560 1.00 26.76 ? 151 ARG B NE  1 
ATOM 1545 C CZ  . ARG B 1 151 ? 118.286 185.993 162.348 1.00 28.52 ? 151 ARG B CZ  1 
ATOM 1546 N NH1 . ARG B 1 151 ? 118.337 186.831 161.325 1.00 25.66 ? 151 ARG B NH1 1 
ATOM 1547 N NH2 . ARG B 1 151 ? 119.319 185.925 163.184 1.00 30.43 ? 151 ARG B NH2 1 
ATOM 1548 N N   . TYR B 1 152 ? 110.471 185.068 162.452 1.00 25.76 ? 152 TYR B N   1 
ATOM 1549 C CA  . TYR B 1 152 ? 109.253 185.783 162.073 1.00 21.78 ? 152 TYR B CA  1 
ATOM 1550 C C   . TYR B 1 152 ? 109.444 187.228 162.531 1.00 23.68 ? 152 TYR B C   1 
ATOM 1551 O O   . TYR B 1 152 ? 109.117 187.579 163.666 1.00 26.45 ? 152 TYR B O   1 
ATOM 1552 C CB  . TYR B 1 152 ? 108.012 185.137 162.689 1.00 17.43 ? 152 TYR B CB  1 
ATOM 1553 C CG  . TYR B 1 152 ? 106.700 185.832 162.372 1.00 23.10 ? 152 TYR B CG  1 
ATOM 1554 C CD1 . TYR B 1 152 ? 106.593 186.724 161.312 1.00 24.33 ? 152 TYR B CD1 1 
ATOM 1555 C CD2 . TYR B 1 152 ? 105.565 185.585 163.131 1.00 27.63 ? 152 TYR B CD2 1 
ATOM 1556 C CE1 . TYR B 1 152 ? 105.399 187.357 161.027 1.00 25.11 ? 152 TYR B CE1 1 
ATOM 1557 C CE2 . TYR B 1 152 ? 104.365 186.211 162.852 1.00 23.82 ? 152 TYR B CE2 1 
ATOM 1558 C CZ  . TYR B 1 152 ? 104.287 187.095 161.799 1.00 24.64 ? 152 TYR B CZ  1 
ATOM 1559 O OH  . TYR B 1 152 ? 103.094 187.720 161.516 1.00 29.62 ? 152 TYR B OH  1 
ATOM 1560 N N   . TYR B 1 153 ? 109.976 188.059 161.639 1.00 30.47 ? 153 TYR B N   1 
ATOM 1561 C CA  . TYR B 1 153 ? 110.246 189.460 161.927 1.00 26.34 ? 153 TYR B CA  1 
ATOM 1562 C C   . TYR B 1 153 ? 109.139 190.308 161.313 1.00 24.83 ? 153 TYR B C   1 
ATOM 1563 O O   . TYR B 1 153 ? 108.875 190.212 160.110 1.00 30.00 ? 153 TYR B O   1 
ATOM 1564 C CB  . TYR B 1 153 ? 111.609 189.880 161.375 1.00 22.54 ? 153 TYR B CB  1 
ATOM 1565 C CG  . TYR B 1 153 ? 112.800 189.380 162.169 1.00 22.15 ? 153 TYR B CG  1 
ATOM 1566 C CD1 . TYR B 1 153 ? 112.665 188.365 163.107 1.00 25.79 ? 153 TYR B CD1 1 
ATOM 1567 C CD2 . TYR B 1 153 ? 114.061 189.925 161.973 1.00 21.51 ? 153 TYR B CD2 1 
ATOM 1568 C CE1 . TYR B 1 153 ? 113.751 187.909 163.827 1.00 26.52 ? 153 TYR B CE1 1 
ATOM 1569 C CE2 . TYR B 1 153 ? 115.153 189.475 162.688 1.00 22.34 ? 153 TYR B CE2 1 
ATOM 1570 C CZ  . TYR B 1 153 ? 114.993 188.468 163.613 1.00 24.14 ? 153 TYR B CZ  1 
ATOM 1571 O OH  . TYR B 1 153 ? 116.080 188.019 164.328 1.00 30.74 ? 153 TYR B OH  1 
ATOM 1572 N N   . ARG B 1 154 ? 108.496 191.133 162.137 1.00 33.17 ? 154 ARG B N   1 
ATOM 1573 C CA  . ARG B 1 154 ? 107.390 191.970 161.684 1.00 29.35 ? 154 ARG B CA  1 
ATOM 1574 C C   . ARG B 1 154 ? 107.563 193.373 162.241 1.00 32.92 ? 154 ARG B C   1 
ATOM 1575 O O   . ARG B 1 154 ? 107.624 193.554 163.461 1.00 30.84 ? 154 ARG B O   1 
ATOM 1576 C CB  . ARG B 1 154 ? 106.041 191.387 162.116 1.00 26.79 ? 154 ARG B CB  1 
ATOM 1577 C CG  . ARG B 1 154 ? 104.843 192.196 161.650 1.00 35.23 ? 154 ARG B CG  1 
ATOM 1578 C CD  . ARG B 1 154 ? 103.541 191.582 162.132 1.00 38.18 ? 154 ARG B CD  1 
ATOM 1579 N NE  . ARG B 1 154 ? 102.379 192.301 161.624 1.00 41.54 ? 154 ARG B NE  1 
ATOM 1580 C CZ  . ARG B 1 154 ? 101.122 191.950 161.857 1.00 43.21 ? 154 ARG B CZ  1 
ATOM 1581 N NH1 . ARG B 1 154 ? 100.824 190.890 162.590 1.00 41.26 ? 154 ARG B NH1 1 
ATOM 1582 N NH2 . ARG B 1 154 ? 100.138 192.682 161.342 1.00 38.29 ? 154 ARG B NH2 1 
ATOM 1583 N N   . GLU B 1 155 ? 107.638 194.359 161.344 1.00 40.15 ? 155 GLU B N   1 
ATOM 1584 C CA  . GLU B 1 155 ? 107.696 195.776 161.712 1.00 35.54 ? 155 GLU B CA  1 
ATOM 1585 C C   . GLU B 1 155 ? 108.869 196.074 162.643 1.00 34.27 ? 155 GLU B C   1 
ATOM 1586 O O   . GLU B 1 155 ? 108.760 196.879 163.569 1.00 37.52 ? 155 GLU B O   1 
ATOM 1587 C CB  . GLU B 1 155 ? 106.377 196.234 162.337 1.00 35.18 ? 155 GLU B CB  1 
ATOM 1588 C CG  . GLU B 1 155 ? 105.203 196.244 161.372 1.00 37.54 ? 155 GLU B CG  1 
ATOM 1589 C CD  . GLU B 1 155 ? 103.867 196.362 162.078 1.00 43.67 ? 155 GLU B CD  1 
ATOM 1590 O OE1 . GLU B 1 155 ? 103.657 195.643 163.078 1.00 43.82 ? 155 GLU B OE1 1 
ATOM 1591 O OE2 . GLU B 1 155 ? 103.029 197.174 161.636 1.00 40.89 ? 155 GLU B OE2 1 
ATOM 1592 N N   . ASN B 1 156 ? 110.003 195.430 162.391 1.00 28.51 ? 156 ASN B N   1 
ATOM 1593 C CA  . ASN B 1 156 ? 111.206 195.626 163.188 1.00 29.54 ? 156 ASN B CA  1 
ATOM 1594 C C   . ASN B 1 156 ? 112.118 196.628 162.493 1.00 30.86 ? 156 ASN B C   1 
ATOM 1595 O O   . ASN B 1 156 ? 112.418 196.482 161.304 1.00 40.39 ? 156 ASN B O   1 
ATOM 1596 C CB  . ASN B 1 156 ? 111.939 194.303 163.406 1.00 31.36 ? 156 ASN B CB  1 
ATOM 1597 C CG  . ASN B 1 156 ? 111.053 193.243 164.023 1.00 30.47 ? 156 ASN B CG  1 
ATOM 1598 O OD1 . ASN B 1 156 ? 110.449 192.435 163.318 1.00 38.20 ? 156 ASN B OD1 1 
ATOM 1599 N ND2 . ASN B 1 156 ? 110.965 193.242 165.347 1.00 35.25 ? 156 ASN B ND2 1 
ATOM 1600 N N   . MET B 1 157 ? 112.552 197.642 163.237 1.00 36.16 ? 157 MET B N   1 
ATOM 1601 C CA  . MET B 1 157 ? 113.413 198.698 162.711 1.00 38.76 ? 157 MET B CA  1 
ATOM 1602 C C   . MET B 1 157 ? 114.851 198.383 163.108 1.00 37.37 ? 157 MET B C   1 
ATOM 1603 O O   . MET B 1 157 ? 115.246 198.580 164.260 1.00 41.20 ? 157 MET B O   1 
ATOM 1604 C CB  . MET B 1 157 ? 112.974 200.064 163.228 1.00 36.94 ? 157 MET B CB  1 
ATOM 1605 C CG  . MET B 1 157 ? 113.115 201.187 162.213 1.00 39.70 ? 157 MET B CG  1 
ATOM 1606 S SD  . MET B 1 157 ? 114.835 201.615 161.878 1.00 53.93 ? 157 MET B SD  1 
ATOM 1607 C CE  . MET B 1 157 ? 115.133 202.839 163.150 1.00 40.79 ? 157 MET B CE  1 
ATOM 1608 N N   . TYR B 1 158 ? 115.631 197.893 162.150 1.00 32.10 ? 158 TYR B N   1 
ATOM 1609 C CA  . TYR B 1 158 ? 117.040 197.573 162.363 1.00 23.33 ? 158 TYR B CA  1 
ATOM 1610 C C   . TYR B 1 158 ? 117.873 198.707 161.779 1.00 30.62 ? 158 TYR B C   1 
ATOM 1611 O O   . TYR B 1 158 ? 118.024 198.818 160.560 1.00 40.92 ? 158 TYR B O   1 
ATOM 1612 C CB  . TYR B 1 158 ? 117.393 196.234 161.725 1.00 31.67 ? 158 TYR B CB  1 
ATOM 1613 C CG  . TYR B 1 158 ? 117.052 195.039 162.584 1.00 28.88 ? 158 TYR B CG  1 
ATOM 1614 C CD1 . TYR B 1 158 ? 117.972 194.523 163.487 1.00 26.36 ? 158 TYR B CD1 1 
ATOM 1615 C CD2 . TYR B 1 158 ? 115.809 194.426 162.492 1.00 24.65 ? 158 TYR B CD2 1 
ATOM 1616 C CE1 . TYR B 1 158 ? 117.664 193.432 164.274 1.00 28.95 ? 158 TYR B CE1 1 
ATOM 1617 C CE2 . TYR B 1 158 ? 115.493 193.334 163.275 1.00 26.22 ? 158 TYR B CE2 1 
ATOM 1618 C CZ  . TYR B 1 158 ? 116.424 192.841 164.163 1.00 31.59 ? 158 TYR B CZ  1 
ATOM 1619 O OH  . TYR B 1 158 ? 116.115 191.754 164.945 1.00 31.35 ? 158 TYR B OH  1 
ATOM 1620 N N   . ARG B 1 159 ? 118.416 199.551 162.653 1.00 31.91 ? 159 ARG B N   1 
ATOM 1621 C CA  . ARG B 1 159 ? 119.230 200.690 162.246 1.00 31.02 ? 159 ARG B CA  1 
ATOM 1622 C C   . ARG B 1 159 ? 120.699 200.331 162.435 1.00 34.81 ? 159 ARG B C   1 
ATOM 1623 O O   . ARG B 1 159 ? 121.180 200.238 163.568 1.00 38.90 ? 159 ARG B O   1 
ATOM 1624 C CB  . ARG B 1 159 ? 118.859 201.936 163.047 1.00 34.09 ? 159 ARG B CB  1 
ATOM 1625 C CG  . ARG B 1 159 ? 119.282 203.238 162.388 1.00 35.39 ? 159 ARG B CG  1 
ATOM 1626 C CD  . ARG B 1 159 ? 118.679 204.438 163.096 1.00 31.48 ? 159 ARG B CD  1 
ATOM 1627 N NE  . ARG B 1 159 ? 118.764 205.646 162.284 1.00 35.04 ? 159 ARG B NE  1 
ATOM 1628 C CZ  . ARG B 1 159 ? 117.877 205.993 161.361 1.00 39.92 ? 159 ARG B CZ  1 
ATOM 1629 N NH1 . ARG B 1 159 ? 116.816 205.246 161.107 1.00 39.44 ? 159 ARG B NH1 1 
ATOM 1630 N NH2 . ARG B 1 159 ? 118.058 207.119 160.677 1.00 35.94 ? 159 ARG B NH2 1 
ATOM 1631 N N   . TYR B 1 160 ? 121.402 200.139 161.323 1.00 20.38 ? 160 TYR B N   1 
ATOM 1632 C CA  . TYR B 1 160 ? 122.817 199.782 161.319 1.00 21.14 ? 160 TYR B CA  1 
ATOM 1633 C C   . TYR B 1 160 ? 123.134 198.562 162.190 1.00 24.15 ? 160 TYR B C   1 
ATOM 1634 O O   . TYR B 1 160 ? 123.936 198.653 163.125 1.00 29.58 ? 160 TYR B O   1 
ATOM 1635 C CB  . TYR B 1 160 ? 123.665 200.974 161.742 1.00 25.04 ? 160 TYR B CB  1 
ATOM 1636 C CG  . TYR B 1 160 ? 123.717 202.097 160.731 1.00 28.24 ? 160 TYR B CG  1 
ATOM 1637 C CD1 . TYR B 1 160 ? 122.652 202.978 160.585 1.00 28.18 ? 160 TYR B CD1 1 
ATOM 1638 C CD2 . TYR B 1 160 ? 124.834 202.283 159.928 1.00 30.07 ? 160 TYR B CD2 1 
ATOM 1639 C CE1 . TYR B 1 160 ? 122.698 204.007 159.664 1.00 26.68 ? 160 TYR B CE1 1 
ATOM 1640 C CE2 . TYR B 1 160 ? 124.889 203.310 159.005 1.00 26.95 ? 160 TYR B CE2 1 
ATOM 1641 C CZ  . TYR B 1 160 ? 123.818 204.168 158.877 1.00 25.00 ? 160 TYR B CZ  1 
ATOM 1642 O OH  . TYR B 1 160 ? 123.868 205.192 157.959 1.00 31.55 ? 160 TYR B OH  1 
ATOM 1643 N N   . PRO B 1 161 ? 122.527 197.406 161.913 1.00 20.42 ? 161 PRO B N   1 
ATOM 1644 C CA  . PRO B 1 161 ? 122.887 196.200 162.665 1.00 18.89 ? 161 PRO B CA  1 
ATOM 1645 C C   . PRO B 1 161 ? 124.186 195.586 162.169 1.00 21.09 ? 161 PRO B C   1 
ATOM 1646 O O   . PRO B 1 161 ? 124.465 195.556 160.968 1.00 24.28 ? 161 PRO B O   1 
ATOM 1647 C CB  . PRO B 1 161 ? 121.694 195.267 162.425 1.00 13.88 ? 161 PRO B CB  1 
ATOM 1648 C CG  . PRO B 1 161 ? 121.184 195.660 161.100 1.00 20.22 ? 161 PRO B CG  1 
ATOM 1649 C CD  . PRO B 1 161 ? 121.470 197.133 160.922 1.00 19.05 ? 161 PRO B CD  1 
ATOM 1650 N N   . ASN B 1 162 ? 124.979 195.091 163.121 1.00 20.79 ? 162 ASN B N   1 
ATOM 1651 C CA  . ASN B 1 162 ? 126.287 194.496 162.840 1.00 15.77 ? 162 ASN B CA  1 
ATOM 1652 C C   . ASN B 1 162 ? 127.177 195.464 162.066 1.00 15.47 ? 162 ASN B C   1 
ATOM 1653 O O   . ASN B 1 162 ? 127.890 195.084 161.134 1.00 27.93 ? 162 ASN B O   1 
ATOM 1654 C CB  . ASN B 1 162 ? 126.140 193.169 162.094 1.00 19.21 ? 162 ASN B CB  1 
ATOM 1655 C CG  . ASN B 1 162 ? 125.219 192.199 162.807 1.00 23.01 ? 162 ASN B CG  1 
ATOM 1656 O OD1 . ASN B 1 162 ? 125.435 191.860 163.969 1.00 23.24 ? 162 ASN B OD1 1 
ATOM 1657 N ND2 . ASN B 1 162 ? 124.184 191.745 162.109 1.00 28.10 ? 162 ASN B ND2 1 
ATOM 1658 N N   . GLN B 1 163 ? 127.135 196.735 162.459 1.00 19.47 ? 163 GLN B N   1 
ATOM 1659 C CA  . GLN B 1 163 ? 127.916 197.766 161.793 1.00 23.52 ? 163 GLN B CA  1 
ATOM 1660 C C   . GLN B 1 163 ? 129.355 197.742 162.292 1.00 28.33 ? 163 GLN B C   1 
ATOM 1661 O O   . GLN B 1 163 ? 129.602 197.672 163.501 1.00 32.85 ? 163 GLN B O   1 
ATOM 1662 C CB  . GLN B 1 163 ? 127.293 199.141 162.031 1.00 17.53 ? 163 GLN B CB  1 
ATOM 1663 C CG  . GLN B 1 163 ? 127.592 200.155 160.940 1.00 25.39 ? 163 GLN B CG  1 
ATOM 1664 C CD  . GLN B 1 163 ? 128.677 201.136 161.337 1.00 28.85 ? 163 GLN B CD  1 
ATOM 1665 O OE1 . GLN B 1 163 ? 129.311 200.987 162.381 1.00 29.13 ? 163 GLN B OE1 1 
ATOM 1666 N NE2 . GLN B 1 163 ? 128.894 202.145 160.505 1.00 31.23 ? 163 GLN B NE2 1 
ATOM 1667 N N   . VAL B 1 164 ? 130.300 197.799 161.362 1.00 28.26 ? 164 VAL B N   1 
ATOM 1668 C CA  . VAL B 1 164 ? 131.723 197.822 161.676 1.00 21.81 ? 164 VAL B CA  1 
ATOM 1669 C C   . VAL B 1 164 ? 132.238 199.208 161.313 1.00 29.00 ? 164 VAL B C   1 
ATOM 1670 O O   . VAL B 1 164 ? 132.574 199.476 160.154 1.00 32.82 ? 164 VAL B O   1 
ATOM 1671 C CB  . VAL B 1 164 ? 132.496 196.727 160.934 1.00 31.55 ? 164 VAL B CB  1 
ATOM 1672 C CG1 . VAL B 1 164 ? 133.941 196.692 161.405 1.00 23.51 ? 164 VAL B CG1 1 
ATOM 1673 C CG2 . VAL B 1 164 ? 131.831 195.376 161.136 1.00 30.10 ? 164 VAL B CG2 1 
ATOM 1674 N N   . TYR B 1 165 ? 132.304 200.099 162.303 1.00 34.19 ? 165 TYR B N   1 
ATOM 1675 C CA  . TYR B 1 165 ? 132.840 201.443 162.097 1.00 28.28 ? 165 TYR B CA  1 
ATOM 1676 C C   . TYR B 1 165 ? 134.351 201.385 162.302 1.00 33.76 ? 165 TYR B C   1 
ATOM 1677 O O   . TYR B 1 165 ? 134.886 201.698 163.367 1.00 40.58 ? 165 TYR B O   1 
ATOM 1678 C CB  . TYR B 1 165 ? 132.173 202.442 163.035 1.00 29.51 ? 165 TYR B CB  1 
ATOM 1679 C CG  . TYR B 1 165 ? 132.112 203.845 162.480 1.00 33.82 ? 165 TYR B CG  1 
ATOM 1680 C CD1 . TYR B 1 165 ? 131.073 204.239 161.646 1.00 33.51 ? 165 TYR B CD1 1 
ATOM 1681 C CD2 . TYR B 1 165 ? 133.096 204.776 162.784 1.00 33.01 ? 165 TYR B CD2 1 
ATOM 1682 C CE1 . TYR B 1 165 ? 131.015 205.521 161.134 1.00 32.79 ? 165 TYR B CE1 1 
ATOM 1683 C CE2 . TYR B 1 165 ? 133.047 206.060 162.276 1.00 29.38 ? 165 TYR B CE2 1 
ATOM 1684 C CZ  . TYR B 1 165 ? 132.004 206.427 161.451 1.00 29.63 ? 165 TYR B CZ  1 
ATOM 1685 O OH  . TYR B 1 165 ? 131.949 207.705 160.944 1.00 33.49 ? 165 TYR B OH  1 
ATOM 1686 N N   . TYR B 1 166 ? 135.046 200.968 161.245 1.00 32.05 ? 166 TYR B N   1 
ATOM 1687 C CA  . TYR B 1 166 ? 136.495 200.779 161.282 1.00 29.32 ? 166 TYR B CA  1 
ATOM 1688 C C   . TYR B 1 166 ? 137.151 202.083 160.851 1.00 34.30 ? 166 TYR B C   1 
ATOM 1689 O O   . TYR B 1 166 ? 137.355 202.340 159.664 1.00 41.73 ? 166 TYR B O   1 
ATOM 1690 C CB  . TYR B 1 166 ? 136.903 199.616 160.385 1.00 26.97 ? 166 TYR B CB  1 
ATOM 1691 C CG  . TYR B 1 166 ? 138.342 199.181 160.545 1.00 34.77 ? 166 TYR B CG  1 
ATOM 1692 C CD1 . TYR B 1 166 ? 138.709 198.284 161.538 1.00 32.51 ? 166 TYR B CD1 1 
ATOM 1693 C CD2 . TYR B 1 166 ? 139.334 199.669 159.705 1.00 32.02 ? 166 TYR B CD2 1 
ATOM 1694 C CE1 . TYR B 1 166 ? 140.022 197.881 161.687 1.00 34.92 ? 166 TYR B CE1 1 
ATOM 1695 C CE2 . TYR B 1 166 ? 140.650 199.274 159.848 1.00 31.55 ? 166 TYR B CE2 1 
ATOM 1696 C CZ  . TYR B 1 166 ? 140.988 198.380 160.842 1.00 35.62 ? 166 TYR B CZ  1 
ATOM 1697 O OH  . TYR B 1 166 ? 142.297 197.984 160.989 1.00 38.33 ? 166 TYR B OH  1 
ATOM 1698 N N   . ARG B 1 167 ? 137.487 202.922 161.830 1.00 33.37 ? 167 ARG B N   1 
ATOM 1699 C CA  . ARG B 1 167 ? 138.088 204.233 161.584 1.00 38.24 ? 167 ARG B CA  1 
ATOM 1700 C C   . ARG B 1 167 ? 139.314 204.418 162.471 1.00 40.68 ? 167 ARG B C   1 
ATOM 1701 O O   . ARG B 1 167 ? 139.295 205.208 163.424 1.00 37.52 ? 167 ARG B O   1 
ATOM 1702 C CB  . ARG B 1 167 ? 137.064 205.345 161.824 1.00 30.11 ? 167 ARG B CB  1 
ATOM 1703 C CG  . ARG B 1 167 ? 137.498 206.730 161.365 1.00 30.04 ? 167 ARG B CG  1 
ATOM 1704 C CD  . ARG B 1 167 ? 136.901 207.081 160.020 1.00 39.27 ? 167 ARG B CD  1 
ATOM 1705 N NE  . ARG B 1 167 ? 137.211 208.450 159.621 1.00 36.94 ? 167 ARG B NE  1 
ATOM 1706 C CZ  . ARG B 1 167 ? 136.340 209.449 159.636 1.00 38.27 ? 167 ARG B CZ  1 
ATOM 1707 N NH1 . ARG B 1 167 ? 135.088 209.269 160.024 1.00 41.74 ? 167 ARG B NH1 1 
ATOM 1708 N NH2 . ARG B 1 167 ? 136.734 210.659 159.252 1.00 39.05 ? 167 ARG B NH2 1 
ATOM 1709 N N   . PRO B 1 168 ? 140.403 203.701 162.192 1.00 38.42 ? 168 PRO B N   1 
ATOM 1710 C CA  . PRO B 1 168 ? 141.639 203.926 162.948 1.00 30.85 ? 168 PRO B CA  1 
ATOM 1711 C C   . PRO B 1 168 ? 142.367 205.177 162.481 1.00 33.12 ? 168 PRO B C   1 
ATOM 1712 O O   . PRO B 1 168 ? 142.403 205.494 161.290 1.00 38.90 ? 168 PRO B O   1 
ATOM 1713 C CB  . PRO B 1 168 ? 142.463 202.665 162.664 1.00 30.80 ? 168 PRO B CB  1 
ATOM 1714 C CG  . PRO B 1 168 ? 141.991 202.209 161.344 1.00 31.95 ? 168 PRO B CG  1 
ATOM 1715 C CD  . PRO B 1 168 ? 140.532 202.566 161.261 1.00 31.88 ? 168 PRO B CD  1 
ATOM 1716 N N   . VAL B 1 169 ? 142.948 205.892 163.442 1.00 37.48 ? 169 VAL B N   1 
ATOM 1717 C CA  . VAL B 1 169 ? 143.724 207.097 163.177 1.00 38.75 ? 169 VAL B CA  1 
ATOM 1718 C C   . VAL B 1 169 ? 145.079 206.957 163.857 1.00 42.93 ? 169 VAL B C   1 
ATOM 1719 O O   . VAL B 1 169 ? 145.145 206.689 165.062 1.00 42.92 ? 169 VAL B O   1 
ATOM 1720 C CB  . VAL B 1 169 ? 143.003 208.367 163.669 1.00 30.52 ? 169 VAL B CB  1 
ATOM 1721 C CG1 . VAL B 1 169 ? 143.825 209.602 163.339 1.00 34.99 ? 169 VAL B CG1 1 
ATOM 1722 C CG2 . VAL B 1 169 ? 141.614 208.465 163.056 1.00 31.16 ? 169 VAL B CG2 1 
ATOM 1723 N N   . ASP B 1 170 ? 146.151 207.141 163.086 1.00 34.93 ? 170 ASP B N   1 
ATOM 1724 C CA  . ASP B 1 170 ? 147.521 207.123 163.602 1.00 29.56 ? 170 ASP B CA  1 
ATOM 1725 C C   . ASP B 1 170 ? 147.813 205.833 164.366 1.00 30.61 ? 170 ASP B C   1 
ATOM 1726 O O   . ASP B 1 170 ? 148.363 205.841 165.469 1.00 34.97 ? 170 ASP B O   1 
ATOM 1727 C CB  . ASP B 1 170 ? 147.790 208.348 164.477 1.00 34.32 ? 170 ASP B CB  1 
ATOM 1728 C CG  . ASP B 1 170 ? 147.538 209.652 163.748 1.00 38.06 ? 170 ASP B CG  1 
ATOM 1729 O OD1 . ASP B 1 170 ? 147.194 209.610 162.549 1.00 42.49 ? 170 ASP B OD1 1 
ATOM 1730 O OD2 . ASP B 1 170 ? 147.684 210.723 164.375 1.00 39.16 ? 170 ASP B OD2 1 
ATOM 1731 N N   . GLN B 1 171 ? 147.435 204.708 163.765 1.00 33.72 ? 171 GLN B N   1 
ATOM 1732 C CA  . GLN B 1 171 ? 147.652 203.400 164.375 1.00 34.83 ? 171 GLN B CA  1 
ATOM 1733 C C   . GLN B 1 171 ? 149.075 202.949 164.066 1.00 33.08 ? 171 GLN B C   1 
ATOM 1734 O O   . GLN B 1 171 ? 149.405 202.663 162.911 1.00 30.74 ? 171 GLN B O   1 
ATOM 1735 C CB  . GLN B 1 171 ? 146.623 202.397 163.860 1.00 25.75 ? 171 GLN B CB  1 
ATOM 1736 C CG  . GLN B 1 171 ? 146.244 201.321 164.862 1.00 28.18 ? 171 GLN B CG  1 
ATOM 1737 C CD  . GLN B 1 171 ? 145.183 200.377 164.329 1.00 28.61 ? 171 GLN B CD  1 
ATOM 1738 O OE1 . GLN B 1 171 ? 145.029 200.220 163.118 1.00 34.46 ? 171 GLN B OE1 1 
ATOM 1739 N NE2 . GLN B 1 171 ? 144.444 199.744 165.232 1.00 23.06 ? 171 GLN B NE2 1 
ATOM 1740 N N   . TYR B 1 172 ? 149.920 202.887 165.093 1.00 33.45 ? 172 TYR B N   1 
ATOM 1741 C CA  . TYR B 1 172 ? 151.313 202.458 164.965 1.00 29.28 ? 172 TYR B CA  1 
ATOM 1742 C C   . TYR B 1 172 ? 151.508 201.241 165.862 1.00 35.69 ? 172 TYR B C   1 
ATOM 1743 O O   . TYR B 1 172 ? 151.979 201.358 166.994 1.00 42.15 ? 172 TYR B O   1 
ATOM 1744 C CB  . TYR B 1 172 ? 152.287 203.592 165.337 1.00 34.16 ? 172 TYR B CB  1 
ATOM 1745 C CG  . TYR B 1 172 ? 152.315 204.754 164.369 1.00 33.89 ? 172 TYR B CG  1 
ATOM 1746 C CD1 . TYR B 1 172 ? 151.287 205.686 164.340 1.00 29.80 ? 172 TYR B CD1 1 
ATOM 1747 C CD2 . TYR B 1 172 ? 153.382 204.929 163.497 1.00 35.67 ? 172 TYR B CD2 1 
ATOM 1748 C CE1 . TYR B 1 172 ? 151.313 206.752 163.461 1.00 32.75 ? 172 TYR B CE1 1 
ATOM 1749 C CE2 . TYR B 1 172 ? 153.417 205.993 162.616 1.00 37.83 ? 172 TYR B CE2 1 
ATOM 1750 C CZ  . TYR B 1 172 ? 152.380 206.900 162.602 1.00 40.65 ? 172 TYR B CZ  1 
ATOM 1751 O OH  . TYR B 1 172 ? 152.411 207.961 161.725 1.00 44.24 ? 172 TYR B OH  1 
ATOM 1752 N N   . ASN B 1 173 ? 151.174 200.064 165.344 1.00 27.02 ? 173 ASN B N   1 
ATOM 1753 C CA  . ASN B 1 173 ? 151.238 198.829 166.115 1.00 23.51 ? 173 ASN B CA  1 
ATOM 1754 C C   . ASN B 1 173 ? 152.249 197.879 165.490 1.00 31.96 ? 173 ASN B C   1 
ATOM 1755 O O   . ASN B 1 173 ? 152.388 197.822 164.264 1.00 35.72 ? 173 ASN B O   1 
ATOM 1756 C CB  . ASN B 1 173 ? 149.868 198.155 166.201 1.00 22.96 ? 173 ASN B CB  1 
ATOM 1757 C CG  . ASN B 1 173 ? 148.876 198.956 167.018 1.00 32.44 ? 173 ASN B CG  1 
ATOM 1758 O OD1 . ASN B 1 173 ? 149.257 199.746 167.880 1.00 38.15 ? 173 ASN B OD1 1 
ATOM 1759 N ND2 . ASN B 1 173 ? 147.591 198.753 166.751 1.00 32.79 ? 173 ASN B ND2 1 
ATOM 1760 N N   . ASN B 1 174 ? 152.950 197.134 166.341 1.00 30.72 ? 174 ASN B N   1 
ATOM 1761 C CA  . ASN B 1 174 ? 153.986 196.203 165.907 1.00 20.94 ? 174 ASN B CA  1 
ATOM 1762 C C   . ASN B 1 174 ? 153.749 194.853 166.562 1.00 25.58 ? 174 ASN B C   1 
ATOM 1763 O O   . ASN B 1 174 ? 153.799 194.738 167.791 1.00 36.65 ? 174 ASN B O   1 
ATOM 1764 C CB  . ASN B 1 174 ? 155.380 196.729 166.257 1.00 19.07 ? 174 ASN B CB  1 
ATOM 1765 C CG  . ASN B 1 174 ? 155.799 197.895 165.387 1.00 30.17 ? 174 ASN B CG  1 
ATOM 1766 O OD1 . ASN B 1 174 ? 155.415 199.038 165.635 1.00 38.76 ? 174 ASN B OD1 1 
ATOM 1767 N ND2 . ASN B 1 174 ? 156.595 197.614 164.361 1.00 26.67 ? 174 ASN B ND2 1 
ATOM 1768 N N   . GLN B 1 175 ? 153.491 193.834 165.742 1.00 29.57 ? 175 GLN B N   1 
ATOM 1769 C CA  . GLN B 1 175 ? 153.392 192.444 166.191 1.00 30.86 ? 175 GLN B CA  1 
ATOM 1770 C C   . GLN B 1 175 ? 154.301 191.632 165.272 1.00 29.89 ? 175 GLN B C   1 
ATOM 1771 O O   . GLN B 1 175 ? 153.846 191.062 164.278 1.00 29.59 ? 175 GLN B O   1 
ATOM 1772 C CB  . GLN B 1 175 ? 151.952 191.945 166.159 1.00 22.86 ? 175 GLN B CB  1 
ATOM 1773 C CG  . GLN B 1 175 ? 151.746 190.605 166.845 1.00 24.78 ? 175 GLN B CG  1 
ATOM 1774 C CD  . GLN B 1 175 ? 150.281 190.251 167.006 1.00 26.54 ? 175 GLN B CD  1 
ATOM 1775 O OE1 . GLN B 1 175 ? 149.442 190.650 166.199 1.00 33.43 ? 175 GLN B OE1 1 
ATOM 1776 N NE2 . GLN B 1 175 ? 149.967 189.501 168.054 1.00 27.21 ? 175 GLN B NE2 1 
ATOM 1777 N N   . ASN B 1 176 ? 155.585 191.577 165.613 1.00 26.95 ? 176 ASN B N   1 
ATOM 1778 C CA  . ASN B 1 176 ? 156.597 190.988 164.751 1.00 26.18 ? 176 ASN B CA  1 
ATOM 1779 C C   . ASN B 1 176 ? 157.278 189.820 165.451 1.00 30.01 ? 176 ASN B C   1 
ATOM 1780 O O   . ASN B 1 176 ? 157.460 189.823 166.671 1.00 30.20 ? 176 ASN B O   1 
ATOM 1781 C CB  . ASN B 1 176 ? 157.647 192.027 164.341 1.00 32.05 ? 176 ASN B CB  1 
ATOM 1782 C CG  . ASN B 1 176 ? 157.032 193.259 163.711 1.00 34.20 ? 176 ASN B CG  1 
ATOM 1783 O OD1 . ASN B 1 176 ? 156.078 193.164 162.939 1.00 35.76 ? 176 ASN B OD1 1 
ATOM 1784 N ND2 . ASN B 1 176 ? 157.573 194.426 164.040 1.00 35.64 ? 176 ASN B ND2 1 
ATOM 1785 N N   . THR B 1 177 ? 157.657 188.822 164.659 1.00 40.26 ? 177 THR B N   1 
ATOM 1786 C CA  . THR B 1 177 ? 158.400 187.665 165.139 1.00 36.19 ? 177 THR B CA  1 
ATOM 1787 C C   . THR B 1 177 ? 159.836 187.773 164.645 1.00 30.76 ? 177 THR B C   1 
ATOM 1788 O O   . THR B 1 177 ? 160.076 187.836 163.434 1.00 36.74 ? 177 THR B O   1 
ATOM 1789 C CB  . THR B 1 177 ? 157.764 186.362 164.658 1.00 32.36 ? 177 THR B CB  1 
ATOM 1790 O OG1 . THR B 1 177 ? 156.434 186.254 165.181 1.00 28.76 ? 177 THR B OG1 1 
ATOM 1791 C CG2 . THR B 1 177 ? 158.586 185.171 165.122 1.00 33.83 ? 177 THR B CG2 1 
ATOM 1792 N N   . PHE B 1 178 ? 160.783 187.795 165.578 1.00 28.92 ? 178 PHE B N   1 
ATOM 1793 C CA  . PHE B 1 178 ? 162.201 187.911 165.261 1.00 29.69 ? 178 PHE B CA  1 
ATOM 1794 C C   . PHE B 1 178 ? 162.911 186.647 165.718 1.00 34.55 ? 178 PHE B C   1 
ATOM 1795 O O   . PHE B 1 178 ? 162.846 186.287 166.898 1.00 39.63 ? 178 PHE B O   1 
ATOM 1796 C CB  . PHE B 1 178 ? 162.814 189.145 165.927 1.00 30.28 ? 178 PHE B CB  1 
ATOM 1797 C CG  . PHE B 1 178 ? 162.682 190.400 165.115 1.00 33.96 ? 178 PHE B CG  1 
ATOM 1798 C CD1 . PHE B 1 178 ? 161.547 191.188 165.213 1.00 33.69 ? 178 PHE B CD1 1 
ATOM 1799 C CD2 . PHE B 1 178 ? 163.693 190.792 164.254 1.00 36.35 ? 178 PHE B CD2 1 
ATOM 1800 C CE1 . PHE B 1 178 ? 161.424 192.344 164.466 1.00 35.22 ? 178 PHE B CE1 1 
ATOM 1801 C CE2 . PHE B 1 178 ? 163.575 191.948 163.505 1.00 38.84 ? 178 PHE B CE2 1 
ATOM 1802 C CZ  . PHE B 1 178 ? 162.438 192.724 163.611 1.00 39.11 ? 178 PHE B CZ  1 
ATOM 1803 N N   . VAL B 1 179 ? 163.586 185.979 164.787 1.00 37.15 ? 179 VAL B N   1 
ATOM 1804 C CA  . VAL B 1 179 ? 164.369 184.785 165.081 1.00 30.20 ? 179 VAL B CA  1 
ATOM 1805 C C   . VAL B 1 179 ? 165.782 185.019 164.574 1.00 26.14 ? 179 VAL B C   1 
ATOM 1806 O O   . VAL B 1 179 ? 165.996 185.166 163.365 1.00 34.27 ? 179 VAL B O   1 
ATOM 1807 C CB  . VAL B 1 179 ? 163.765 183.523 164.442 1.00 29.16 ? 179 VAL B CB  1 
ATOM 1808 C CG1 . VAL B 1 179 ? 164.744 182.363 164.532 1.00 29.18 ? 179 VAL B CG1 1 
ATOM 1809 C CG2 . VAL B 1 179 ? 162.454 183.166 165.118 1.00 28.26 ? 179 VAL B CG2 1 
ATOM 1810 N N   . HIS B 1 180 ? 166.743 185.056 165.494 1.00 30.99 ? 180 HIS B N   1 
ATOM 1811 C CA  . HIS B 1 180 ? 168.152 185.235 165.163 1.00 35.83 ? 180 HIS B CA  1 
ATOM 1812 C C   . HIS B 1 180 ? 168.906 184.004 165.645 1.00 34.92 ? 180 HIS B C   1 
ATOM 1813 O O   . HIS B 1 180 ? 169.117 183.831 166.850 1.00 41.11 ? 180 HIS B O   1 
ATOM 1814 C CB  . HIS B 1 180 ? 168.710 186.509 165.796 1.00 37.66 ? 180 HIS B CB  1 
ATOM 1815 C CG  . HIS B 1 180 ? 168.446 187.746 164.996 1.00 37.42 ? 180 HIS B CG  1 
ATOM 1816 N ND1 . HIS B 1 180 ? 169.337 188.795 164.931 1.00 35.05 ? 180 HIS B ND1 1 
ATOM 1817 C CD2 . HIS B 1 180 ? 167.391 188.101 164.226 1.00 38.81 ? 180 HIS B CD2 1 
ATOM 1818 C CE1 . HIS B 1 180 ? 168.843 189.744 164.156 1.00 41.71 ? 180 HIS B CE1 1 
ATOM 1819 N NE2 . HIS B 1 180 ? 167.663 189.347 163.714 1.00 38.77 ? 180 HIS B NE2 1 
ATOM 1820 N N   . ASP B 1 181 ? 169.308 183.152 164.706 1.00 45.73 ? 181 ASP B N   1 
ATOM 1821 C CA  . ASP B 1 181 ? 170.016 181.917 165.012 1.00 45.25 ? 181 ASP B CA  1 
ATOM 1822 C C   . ASP B 1 181 ? 171.384 181.956 164.351 1.00 44.49 ? 181 ASP B C   1 
ATOM 1823 O O   . ASP B 1 181 ? 171.479 182.082 163.125 1.00 43.21 ? 181 ASP B O   1 
ATOM 1824 C CB  . ASP B 1 181 ? 169.223 180.698 164.538 1.00 41.27 ? 181 ASP B CB  1 
ATOM 1825 C CG  . ASP B 1 181 ? 169.767 179.397 165.093 1.00 47.44 ? 181 ASP B CG  1 
ATOM 1826 O OD1 . ASP B 1 181 ? 169.629 179.166 166.312 1.00 50.55 ? 181 ASP B OD1 1 
ATOM 1827 O OD2 . ASP B 1 181 ? 170.333 178.607 164.309 1.00 46.95 ? 181 ASP B OD2 1 
ATOM 1828 N N   . CYS B 1 182 ? 172.436 181.844 165.163 1.00 41.99 ? 182 CYS B N   1 
ATOM 1829 C CA  . CYS B 1 182 ? 173.816 181.800 164.678 1.00 37.09 ? 182 CYS B CA  1 
ATOM 1830 C C   . CYS B 1 182 ? 174.153 183.025 163.832 1.00 39.66 ? 182 CYS B C   1 
ATOM 1831 O O   . CYS B 1 182 ? 174.779 182.922 162.776 1.00 43.22 ? 182 CYS B O   1 
ATOM 1832 C CB  . CYS B 1 182 ? 174.077 180.512 163.898 1.00 40.47 ? 182 CYS B CB  1 
ATOM 1833 S SG  . CYS B 1 182 ? 174.086 179.032 164.925 1.00 63.20 ? 182 CYS B SG  1 
ATOM 1834 N N   . VAL B 1 183 ? 173.738 184.195 164.301 1.00 36.16 ? 183 VAL B N   1 
ATOM 1835 C CA  . VAL B 1 183 ? 173.985 185.452 163.607 1.00 33.28 ? 183 VAL B CA  1 
ATOM 1836 C C   . VAL B 1 183 ? 175.177 186.142 164.251 1.00 24.08 ? 183 VAL B C   1 
ATOM 1837 O O   . VAL B 1 183 ? 175.443 185.985 165.448 1.00 36.03 ? 183 VAL B O   1 
ATOM 1838 C CB  . VAL B 1 183 ? 172.735 186.358 163.628 1.00 33.36 ? 183 VAL B CB  1 
ATOM 1839 C CG1 . VAL B 1 183 ? 173.046 187.714 163.009 1.00 35.78 ? 183 VAL B CG1 1 
ATOM 1840 C CG2 . VAL B 1 183 ? 171.584 185.687 162.899 1.00 30.11 ? 183 VAL B CG2 1 
ATOM 1841 N N   . ASN B 1 184 ? 175.903 186.916 163.442 1.00 27.82 ? 184 ASN B N   1 
ATOM 1842 C CA  . ASN B 1 184 ? 177.069 187.676 163.897 1.00 35.27 ? 184 ASN B CA  1 
ATOM 1843 C C   . ASN B 1 184 ? 178.119 186.767 164.532 1.00 32.20 ? 184 ASN B C   1 
ATOM 1844 O O   . ASN B 1 184 ? 178.712 187.095 165.562 1.00 29.28 ? 184 ASN B O   1 
ATOM 1845 C CB  . ASN B 1 184 ? 176.659 188.791 164.863 1.00 33.08 ? 184 ASN B CB  1 
ATOM 1846 C CG  . ASN B 1 184 ? 175.842 189.877 164.187 1.00 32.32 ? 184 ASN B CG  1 
ATOM 1847 O OD1 . ASN B 1 184 ? 175.296 189.673 163.104 1.00 34.08 ? 184 ASN B OD1 1 
ATOM 1848 N ND2 . ASN B 1 184 ? 175.757 191.037 164.826 1.00 34.73 ? 184 ASN B ND2 1 
ATOM 1849 N N   . ILE B 1 185 ? 178.353 185.615 163.913 1.00 30.52 ? 185 ILE B N   1 
ATOM 1850 C CA  . ILE B 1 185 ? 179.387 184.687 164.357 1.00 30.93 ? 185 ILE B CA  1 
ATOM 1851 C C   . ILE B 1 185 ? 180.688 185.059 163.659 1.00 27.44 ? 185 ILE B C   1 
ATOM 1852 O O   . ILE B 1 185 ? 180.753 185.087 162.425 1.00 31.09 ? 185 ILE B O   1 
ATOM 1853 C CB  . ILE B 1 185 ? 178.996 183.232 164.062 1.00 30.18 ? 185 ILE B CB  1 
ATOM 1854 C CG1 . ILE B 1 185 ? 177.780 182.828 164.896 1.00 30.01 ? 185 ILE B CG1 1 
ATOM 1855 C CG2 . ILE B 1 185 ? 180.171 182.304 164.331 1.00 27.74 ? 185 ILE B CG2 1 
ATOM 1856 C CD1 . ILE B 1 185 ? 177.496 181.342 164.882 1.00 30.44 ? 185 ILE B CD1 1 
ATOM 1857 N N   . THR B 1 186 ? 181.723 185.341 164.444 1.00 27.62 ? 186 THR B N   1 
ATOM 1858 C CA  . THR B 1 186 ? 182.995 185.810 163.911 1.00 33.30 ? 186 THR B CA  1 
ATOM 1859 C C   . THR B 1 186 ? 184.133 184.972 164.473 1.00 30.62 ? 186 THR B C   1 
ATOM 1860 O O   . THR B 1 186 ? 184.248 184.810 165.692 1.00 24.31 ? 186 THR B O   1 
ATOM 1861 C CB  . THR B 1 186 ? 183.222 187.290 164.240 1.00 34.76 ? 186 THR B CB  1 
ATOM 1862 O OG1 . THR B 1 186 ? 182.128 188.065 163.736 1.00 42.10 ? 186 THR B OG1 1 
ATOM 1863 C CG2 . THR B 1 186 ? 184.518 187.783 163.614 1.00 33.05 ? 186 THR B CG2 1 
ATOM 1864 N N   . VAL B 1 187 ? 184.968 184.446 163.581 1.00 28.27 ? 187 VAL B N   1 
ATOM 1865 C CA  . VAL B 1 187 ? 186.216 183.783 163.942 1.00 27.56 ? 187 VAL B CA  1 
ATOM 1866 C C   . VAL B 1 187 ? 187.311 184.533 163.197 1.00 26.51 ? 187 VAL B C   1 
ATOM 1867 O O   . VAL B 1 187 ? 187.540 184.296 162.005 1.00 36.66 ? 187 VAL B O   1 
ATOM 1868 C CB  . VAL B 1 187 ? 186.214 182.292 163.588 1.00 28.93 ? 187 VAL B CB  1 
ATOM 1869 C CG1 . VAL B 1 187 ? 187.440 181.610 164.168 1.00 29.77 ? 187 VAL B CG1 1 
ATOM 1870 C CG2 . VAL B 1 187 ? 184.941 181.627 164.092 1.00 30.31 ? 187 VAL B CG2 1 
ATOM 1871 N N   . LYS B 1 188 ? 187.996 185.440 163.891 1.00 23.75 ? 188 LYS B N   1 
ATOM 1872 C CA  . LYS B 1 188 ? 188.885 186.390 163.243 1.00 29.88 ? 188 LYS B CA  1 
ATOM 1873 C C   . LYS B 1 188 ? 190.198 186.486 164.006 1.00 28.73 ? 188 LYS B C   1 
ATOM 1874 O O   . LYS B 1 188 ? 190.251 186.250 165.214 1.00 41.12 ? 188 LYS B O   1 
ATOM 1875 C CB  . LYS B 1 188 ? 188.229 187.778 163.145 1.00 29.75 ? 188 LYS B CB  1 
ATOM 1876 C CG  . LYS B 1 188 ? 188.947 188.768 162.241 1.00 28.86 ? 188 LYS B CG  1 
ATOM 1877 C CD  . LYS B 1 188 ? 188.329 190.152 162.341 1.00 27.86 ? 188 LYS B CD  1 
ATOM 1878 C CE  . LYS B 1 188 ? 189.068 191.152 161.467 1.00 38.02 ? 188 LYS B CE  1 
ATOM 1879 N NZ  . LYS B 1 188 ? 188.612 192.549 161.709 1.00 31.08 ? 188 LYS B NZ  1 
ATOM 1880 N N   . GLN B 1 189 ? 191.261 186.823 163.279 1.00 38.59 ? 189 GLN B N   1 
ATOM 1881 C CA  . GLN B 1 189 ? 192.550 187.175 163.869 1.00 40.40 ? 189 GLN B CA  1 
ATOM 1882 C C   . GLN B 1 189 ? 192.973 188.512 163.280 1.00 42.87 ? 189 GLN B C   1 
ATOM 1883 O O   . GLN B 1 189 ? 193.296 188.598 162.090 1.00 47.50 ? 189 GLN B O   1 
ATOM 1884 C CB  . GLN B 1 189 ? 193.602 186.096 163.607 1.00 40.37 ? 189 GLN B CB  1 
ATOM 1885 C CG  . GLN B 1 189 ? 193.463 185.387 162.272 1.00 44.91 ? 189 GLN B CG  1 
ATOM 1886 C CD  . GLN B 1 189 ? 194.447 184.245 162.119 1.00 46.36 ? 189 GLN B CD  1 
ATOM 1887 O OE1 . GLN B 1 189 ? 195.273 183.999 162.998 1.00 46.81 ? 189 GLN B OE1 1 
ATOM 1888 N NE2 . GLN B 1 189 ? 194.367 183.539 160.996 1.00 41.98 ? 189 GLN B NE2 1 
ATOM 1889 N N   . HIS B 1 190 ? 192.969 189.556 164.106 1.00 35.85 ? 190 HIS B N   1 
ATOM 1890 C CA  . HIS B 1 190 ? 193.229 190.915 163.658 1.00 37.93 ? 190 HIS B CA  1 
ATOM 1891 C C   . HIS B 1 190 ? 194.469 191.467 164.345 1.00 33.62 ? 190 HIS B C   1 
ATOM 1892 O O   . HIS B 1 190 ? 194.659 191.279 165.551 1.00 42.85 ? 190 HIS B O   1 
ATOM 1893 C CB  . HIS B 1 190 ? 192.027 191.823 163.936 1.00 42.39 ? 190 HIS B CB  1 
ATOM 1894 C CG  . HIS B 1 190 ? 192.207 193.228 163.456 1.00 40.73 ? 190 HIS B CG  1 
ATOM 1895 N ND1 . HIS B 1 190 ? 192.918 193.541 162.317 1.00 44.85 ? 190 HIS B ND1 1 
ATOM 1896 C CD2 . HIS B 1 190 ? 191.764 194.406 163.957 1.00 41.50 ? 190 HIS B CD2 1 
ATOM 1897 C CE1 . HIS B 1 190 ? 192.910 194.850 162.140 1.00 44.48 ? 190 HIS B CE1 1 
ATOM 1898 N NE2 . HIS B 1 190 ? 192.215 195.398 163.120 1.00 42.65 ? 190 HIS B NE2 1 
ATOM 1899 N N   . THR B 1 191 ? 195.310 192.147 163.570 1.00 34.10 ? 191 THR B N   1 
ATOM 1900 C CA  . THR B 1 191 ? 196.536 192.748 164.076 1.00 41.72 ? 191 THR B CA  1 
ATOM 1901 C C   . THR B 1 191 ? 196.624 194.187 163.591 1.00 42.88 ? 191 THR B C   1 
ATOM 1902 O O   . THR B 1 191 ? 196.425 194.457 162.403 1.00 44.24 ? 191 THR B O   1 
ATOM 1903 C CB  . THR B 1 191 ? 197.773 191.966 163.619 1.00 41.33 ? 191 THR B CB  1 
ATOM 1904 O OG1 . THR B 1 191 ? 197.704 190.626 164.119 1.00 42.79 ? 191 THR B OG1 1 
ATOM 1905 C CG2 . THR B 1 191 ? 199.043 192.624 164.135 1.00 39.36 ? 191 THR B CG2 1 
ATOM 1906 N N   . VAL B 1 192 ? 196.921 195.103 164.508 1.00 40.34 ? 192 VAL B N   1 
ATOM 1907 C CA  . VAL B 1 192 ? 197.117 196.511 164.189 1.00 37.48 ? 192 VAL B CA  1 
ATOM 1908 C C   . VAL B 1 192 ? 198.548 196.875 164.551 1.00 39.45 ? 192 VAL B C   1 
ATOM 1909 O O   . VAL B 1 192 ? 198.972 196.683 165.698 1.00 46.10 ? 192 VAL B O   1 
ATOM 1910 C CB  . VAL B 1 192 ? 196.118 197.413 164.932 1.00 41.29 ? 192 VAL B CB  1 
ATOM 1911 C CG1 . VAL B 1 192 ? 196.296 198.862 164.506 1.00 45.82 ? 192 VAL B CG1 1 
ATOM 1912 C CG2 . VAL B 1 192 ? 194.695 196.947 164.679 1.00 39.03 ? 192 VAL B CG2 1 
ATOM 1913 N N   . THR B 1 193 ? 199.291 197.395 163.578 1.00 48.16 ? 193 THR B N   1 
ATOM 1914 C CA  . THR B 1 193 ? 200.678 197.794 163.771 1.00 50.71 ? 193 THR B CA  1 
ATOM 1915 C C   . THR B 1 193 ? 200.814 199.284 163.502 1.00 49.11 ? 193 THR B C   1 
ATOM 1916 O O   . THR B 1 193 ? 200.436 199.763 162.427 1.00 49.10 ? 193 THR B O   1 
ATOM 1917 C CB  . THR B 1 193 ? 201.618 197.005 162.854 1.00 52.40 ? 193 THR B CB  1 
ATOM 1918 O OG1 . THR B 1 193 ? 201.443 195.601 163.080 1.00 48.44 ? 193 THR B OG1 1 
ATOM 1919 C CG2 . THR B 1 193 ? 203.067 197.383 163.125 1.00 51.56 ? 193 THR B CG2 1 
ATOM 1920 N N   . THR B 1 194 ? 201.355 200.014 164.479 1.00 46.47 ? 194 THR B N   1 
ATOM 1921 C CA  . THR B 1 194 ? 201.595 201.454 164.355 1.00 49.09 ? 194 THR B CA  1 
ATOM 1922 C C   . THR B 1 194 ? 202.957 201.740 164.986 1.00 50.70 ? 194 THR B C   1 
ATOM 1923 O O   . THR B 1 194 ? 203.057 201.984 166.191 1.00 52.14 ? 194 THR B O   1 
ATOM 1924 C CB  . THR B 1 194 ? 200.487 202.267 165.013 1.00 49.30 ? 194 THR B CB  1 
ATOM 1925 O OG1 . THR B 1 194 ? 199.213 201.815 164.536 1.00 46.94 ? 194 THR B OG1 1 
ATOM 1926 C CG2 . THR B 1 194 ? 200.647 203.744 164.684 1.00 47.45 ? 194 THR B CG2 1 
ATOM 1927 N N   . THR B 1 195 ? 204.000 201.705 164.163 1.00 49.04 ? 195 THR B N   1 
ATOM 1928 C CA  . THR B 1 195 ? 205.367 201.928 164.611 1.00 53.61 ? 195 THR B CA  1 
ATOM 1929 C C   . THR B 1 195 ? 205.892 203.226 164.014 1.00 52.35 ? 195 THR B C   1 
ATOM 1930 O O   . THR B 1 195 ? 205.803 203.438 162.800 1.00 49.17 ? 195 THR B O   1 
ATOM 1931 C CB  . THR B 1 195 ? 206.275 200.761 164.215 1.00 50.40 ? 195 THR B CB  1 
ATOM 1932 O OG1 . THR B 1 195 ? 205.745 199.540 164.745 1.00 52.03 ? 195 THR B OG1 1 
ATOM 1933 C CG2 . THR B 1 195 ? 207.680 200.975 164.757 1.00 51.02 ? 195 THR B CG2 1 
ATOM 1934 N N   . THR B 1 196 ? 206.435 204.088 164.869 1.00 53.59 ? 196 THR B N   1 
ATOM 1935 C CA  . THR B 1 196 ? 206.999 205.365 164.455 1.00 52.66 ? 196 THR B CA  1 
ATOM 1936 C C   . THR B 1 196 ? 208.498 205.392 164.714 1.00 54.50 ? 196 THR B C   1 
ATOM 1937 O O   . THR B 1 196 ? 208.936 205.178 165.849 1.00 53.08 ? 196 THR B O   1 
ATOM 1938 C CB  . THR B 1 196 ? 206.344 206.526 165.206 1.00 55.14 ? 196 THR B CB  1 
ATOM 1939 O OG1 . THR B 1 196 ? 204.917 206.407 165.123 1.00 54.11 ? 196 THR B OG1 1 
ATOM 1940 C CG2 . THR B 1 196 ? 206.771 207.857 164.606 1.00 55.02 ? 196 THR B CG2 1 
ATOM 1941 N N   . LYS B 1 197 ? 209.268 205.665 163.658 1.00 65.56 ? 197 LYS B N   1 
ATOM 1942 C CA  . LYS B 1 197 ? 210.734 205.737 163.684 1.00 65.81 ? 197 LYS B CA  1 
ATOM 1943 C C   . LYS B 1 197 ? 211.339 204.599 164.506 1.00 65.64 ? 197 LYS B C   1 
ATOM 1944 O O   . LYS B 1 197 ? 212.201 204.798 165.366 1.00 64.86 ? 197 LYS B O   1 
ATOM 1945 C CB  . LYS B 1 197 ? 211.239 207.105 164.165 1.00 64.87 ? 197 LYS B CB  1 
ATOM 1946 C CG  . LYS B 1 197 ? 210.736 207.580 165.523 1.00 62.96 ? 197 LYS B CG  1 
ATOM 1947 C CD  . LYS B 1 197 ? 211.353 208.916 165.902 1.00 64.76 ? 197 LYS B CD  1 
ATOM 1948 C CE  . LYS B 1 197 ? 210.784 210.046 165.058 1.00 65.57 ? 197 LYS B CE  1 
ATOM 1949 N NZ  . LYS B 1 197 ? 209.313 210.188 165.236 1.00 63.84 ? 197 LYS B NZ  1 
ATOM 1950 N N   . GLY B 1 198 ? 210.879 203.384 164.223 1.00 60.50 ? 198 GLY B N   1 
ATOM 1951 C CA  . GLY B 1 198 ? 211.439 202.202 164.851 1.00 59.33 ? 198 GLY B CA  1 
ATOM 1952 C C   . GLY B 1 198 ? 212.742 201.785 164.202 1.00 59.91 ? 198 GLY B C   1 
ATOM 1953 O O   . GLY B 1 198 ? 212.762 201.406 163.027 1.00 61.04 ? 198 GLY B O   1 
ATOM 1954 N N   . GLU B 1 199 ? 213.837 201.850 164.954 1.00 58.39 ? 199 GLU B N   1 
ATOM 1955 C CA  . GLU B 1 199 ? 215.171 201.607 164.423 1.00 60.87 ? 199 GLU B CA  1 
ATOM 1956 C C   . GLU B 1 199 ? 215.753 200.335 165.023 1.00 60.52 ? 199 GLU B C   1 
ATOM 1957 O O   . GLU B 1 199 ? 215.773 200.174 166.248 1.00 59.17 ? 199 GLU B O   1 
ATOM 1958 C CB  . GLU B 1 199 ? 216.094 202.794 164.710 1.00 62.13 ? 199 GLU B CB  1 
ATOM 1959 C CG  . GLU B 1 199 ? 215.686 204.079 164.010 1.00 63.39 ? 199 GLU B CG  1 
ATOM 1960 C CD  . GLU B 1 199 ? 216.496 205.276 164.470 1.00 64.46 ? 199 GLU B CD  1 
ATOM 1961 O OE1 . GLU B 1 199 ? 217.010 205.245 165.607 1.00 61.74 ? 199 GLU B OE1 1 
ATOM 1962 O OE2 . GLU B 1 199 ? 216.618 206.246 163.693 1.00 64.33 ? 199 GLU B OE2 1 
ATOM 1963 N N   . ASN B 1 200 ? 216.228 199.440 164.153 1.00 68.57 ? 200 ASN B N   1 
ATOM 1964 C CA  . ASN B 1 200 ? 216.948 198.230 164.556 1.00 68.12 ? 200 ASN B CA  1 
ATOM 1965 C C   . ASN B 1 200 ? 216.128 197.371 165.516 1.00 63.31 ? 200 ASN B C   1 
ATOM 1966 O O   . ASN B 1 200 ? 216.655 196.811 166.479 1.00 63.03 ? 200 ASN B O   1 
ATOM 1967 C CB  . ASN B 1 200 ? 218.305 198.578 165.170 1.00 65.91 ? 200 ASN B CB  1 
ATOM 1968 C CG  . ASN B 1 200 ? 219.153 199.442 164.257 1.00 68.81 ? 200 ASN B CG  1 
ATOM 1969 O OD1 . ASN B 1 200 ? 219.134 200.669 164.351 1.00 69.14 ? 200 ASN B OD1 1 
ATOM 1970 N ND2 . ASN B 1 200 ? 219.902 198.803 163.365 1.00 67.93 ? 200 ASN B ND2 1 
ATOM 1971 N N   . PHE B 1 201 ? 214.830 197.250 165.249 1.00 51.68 ? 201 PHE B N   1 
ATOM 1972 C CA  . PHE B 1 201 ? 213.940 196.477 166.099 1.00 54.38 ? 201 PHE B CA  1 
ATOM 1973 C C   . PHE B 1 201 ? 213.310 195.337 165.309 1.00 52.48 ? 201 PHE B C   1 
ATOM 1974 O O   . PHE B 1 201 ? 213.081 195.446 164.101 1.00 53.11 ? 201 PHE B O   1 
ATOM 1975 C CB  . PHE B 1 201 ? 212.853 197.369 166.727 1.00 55.05 ? 201 PHE B CB  1 
ATOM 1976 C CG  . PHE B 1 201 ? 211.603 197.504 165.899 1.00 56.16 ? 201 PHE B CG  1 
ATOM 1977 C CD1 . PHE B 1 201 ? 211.484 198.518 164.964 1.00 52.21 ? 201 PHE B CD1 1 
ATOM 1978 C CD2 . PHE B 1 201 ? 210.533 196.639 166.080 1.00 54.54 ? 201 PHE B CD2 1 
ATOM 1979 C CE1 . PHE B 1 201 ? 210.334 198.652 164.211 1.00 50.84 ? 201 PHE B CE1 1 
ATOM 1980 C CE2 . PHE B 1 201 ? 209.383 196.768 165.327 1.00 51.94 ? 201 PHE B CE2 1 
ATOM 1981 C CZ  . PHE B 1 201 ? 209.283 197.777 164.391 1.00 52.23 ? 201 PHE B CZ  1 
ATOM 1982 N N   . THR B 1 202 ? 213.036 194.241 166.007 1.00 52.32 ? 202 THR B N   1 
ATOM 1983 C CA  . THR B 1 202 ? 212.440 193.050 165.417 1.00 53.03 ? 202 THR B CA  1 
ATOM 1984 C C   . THR B 1 202 ? 211.007 192.905 165.908 1.00 50.78 ? 202 THR B C   1 
ATOM 1985 O O   . THR B 1 202 ? 210.751 192.956 167.115 1.00 53.86 ? 202 THR B O   1 
ATOM 1986 C CB  . THR B 1 202 ? 213.247 191.799 165.771 1.00 50.28 ? 202 THR B CB  1 
ATOM 1987 O OG1 . THR B 1 202 ? 214.588 191.939 165.283 1.00 53.98 ? 202 THR B OG1 1 
ATOM 1988 C CG2 . THR B 1 202 ? 212.615 190.562 165.151 1.00 50.97 ? 202 THR B CG2 1 
ATOM 1989 N N   . GLU B 1 203 ? 210.080 192.728 164.971 1.00 51.17 ? 203 GLU B N   1 
ATOM 1990 C CA  . GLU B 1 203 ? 208.666 192.557 165.277 1.00 48.56 ? 203 GLU B CA  1 
ATOM 1991 C C   . GLU B 1 203 ? 208.234 191.148 164.900 1.00 50.88 ? 203 GLU B C   1 
ATOM 1992 O O   . GLU B 1 203 ? 208.431 190.719 163.758 1.00 53.33 ? 203 GLU B O   1 
ATOM 1993 C CB  . GLU B 1 203 ? 207.818 193.588 164.530 1.00 52.89 ? 203 GLU B CB  1 
ATOM 1994 C CG  . GLU B 1 203 ? 206.336 193.520 164.856 1.00 56.11 ? 203 GLU B CG  1 
ATOM 1995 C CD  . GLU B 1 203 ? 205.533 194.584 164.137 1.00 55.62 ? 203 GLU B CD  1 
ATOM 1996 O OE1 . GLU B 1 203 ? 206.128 195.354 163.355 1.00 53.41 ? 203 GLU B OE1 1 
ATOM 1997 O OE2 . GLU B 1 203 ? 204.305 194.648 164.354 1.00 55.09 ? 203 GLU B OE2 1 
ATOM 1998 N N   . THR B 1 204 ? 207.649 190.433 165.858 1.00 52.68 ? 204 THR B N   1 
ATOM 1999 C CA  . THR B 1 204 ? 207.162 189.078 165.638 1.00 54.63 ? 204 THR B CA  1 
ATOM 2000 C C   . THR B 1 204 ? 205.699 189.002 166.044 1.00 51.93 ? 204 THR B C   1 
ATOM 2001 O O   . THR B 1 204 ? 205.355 189.297 167.193 1.00 57.57 ? 204 THR B O   1 
ATOM 2002 C CB  . THR B 1 204 ? 207.984 188.055 166.430 1.00 53.25 ? 204 THR B CB  1 
ATOM 2003 O OG1 . THR B 1 204 ? 209.361 188.145 166.046 1.00 55.87 ? 204 THR B OG1 1 
ATOM 2004 C CG2 . THR B 1 204 ? 207.479 186.646 166.162 1.00 52.63 ? 204 THR B CG2 1 
ATOM 2005 N N   . ASP B 1 205 ? 204.847 188.591 165.107 1.00 44.95 ? 205 ASP B N   1 
ATOM 2006 C CA  . ASP B 1 205 ? 203.406 188.476 165.328 1.00 45.63 ? 205 ASP B CA  1 
ATOM 2007 C C   . ASP B 1 205 ? 202.959 187.110 164.817 1.00 48.71 ? 205 ASP B C   1 
ATOM 2008 O O   . ASP B 1 205 ? 202.732 186.932 163.617 1.00 55.01 ? 205 ASP B O   1 
ATOM 2009 C CB  . ASP B 1 205 ? 202.646 189.600 164.627 1.00 51.54 ? 205 ASP B CB  1 
ATOM 2010 C CG  . ASP B 1 205 ? 202.851 190.950 165.289 1.00 56.86 ? 205 ASP B CG  1 
ATOM 2011 O OD1 . ASP B 1 205 ? 203.338 190.988 166.437 1.00 54.93 ? 205 ASP B OD1 1 
ATOM 2012 O OD2 . ASP B 1 205 ? 202.524 191.977 164.658 1.00 56.78 ? 205 ASP B OD2 1 
ATOM 2013 N N   . ILE B 1 206 ? 202.836 186.147 165.726 1.00 41.34 ? 206 ILE B N   1 
ATOM 2014 C CA  . ILE B 1 206 ? 202.403 184.794 165.398 1.00 44.19 ? 206 ILE B CA  1 
ATOM 2015 C C   . ILE B 1 206 ? 201.058 184.548 166.063 1.00 39.49 ? 206 ILE B C   1 
ATOM 2016 O O   . ILE B 1 206 ? 200.918 184.720 167.280 1.00 43.70 ? 206 ILE B O   1 
ATOM 2017 C CB  . ILE B 1 206 ? 203.436 183.745 165.843 1.00 37.28 ? 206 ILE B CB  1 
ATOM 2018 C CG1 . ILE B 1 206 ? 204.807 184.057 165.243 1.00 41.77 ? 206 ILE B CG1 1 
ATOM 2019 C CG2 . ILE B 1 206 ? 202.983 182.350 165.440 1.00 33.21 ? 206 ILE B CG2 1 
ATOM 2020 C CD1 . ILE B 1 206 ? 205.884 183.074 165.644 1.00 42.50 ? 206 ILE B CD1 1 
ATOM 2021 N N   . LYS B 1 207 ? 200.068 184.151 165.265 1.00 36.66 ? 207 LYS B N   1 
ATOM 2022 C CA  . LYS B 1 207 ? 198.725 183.837 165.753 1.00 35.07 ? 207 LYS B CA  1 
ATOM 2023 C C   . LYS B 1 207 ? 198.347 182.472 165.189 1.00 37.98 ? 207 LYS B C   1 
ATOM 2024 O O   . LYS B 1 207 ? 197.757 182.377 164.108 1.00 43.11 ? 207 LYS B O   1 
ATOM 2025 C CB  . LYS B 1 207 ? 197.727 184.920 165.359 1.00 40.96 ? 207 LYS B CB  1 
ATOM 2026 C CG  . LYS B 1 207 ? 197.969 186.255 166.038 1.00 41.93 ? 207 LYS B CG  1 
ATOM 2027 C CD  . LYS B 1 207 ? 196.892 187.262 165.683 1.00 39.80 ? 207 LYS B CD  1 
ATOM 2028 C CE  . LYS B 1 207 ? 197.077 188.550 166.463 1.00 40.21 ? 207 LYS B CE  1 
ATOM 2029 N NZ  . LYS B 1 207 ? 198.264 189.315 165.992 1.00 41.69 ? 207 LYS B NZ  1 
ATOM 2030 N N   . MET B 1 208 ? 198.692 181.417 165.920 1.00 49.38 ? 208 MET B N   1 
ATOM 2031 C CA  . MET B 1 208 ? 198.303 180.073 165.521 1.00 46.82 ? 208 MET B CA  1 
ATOM 2032 C C   . MET B 1 208 ? 196.807 179.881 165.729 1.00 42.45 ? 208 MET B C   1 
ATOM 2033 O O   . MET B 1 208 ? 196.247 180.298 166.746 1.00 51.23 ? 208 MET B O   1 
ATOM 2034 C CB  . MET B 1 208 ? 199.072 179.032 166.334 1.00 47.70 ? 208 MET B CB  1 
ATOM 2035 C CG  . MET B 1 208 ? 200.564 178.998 166.052 1.00 51.54 ? 208 MET B CG  1 
ATOM 2036 S SD  . MET B 1 208 ? 201.431 177.813 167.100 1.00 68.67 ? 208 MET B SD  1 
ATOM 2037 C CE  . MET B 1 208 ? 203.123 178.064 166.567 1.00 54.38 ? 208 MET B CE  1 
ATOM 2038 N N   . MET B 1 209 ? 196.155 179.253 164.752 1.00 44.54 ? 209 MET B N   1 
ATOM 2039 C CA  . MET B 1 209 ? 194.709 179.019 164.786 1.00 45.03 ? 209 MET B CA  1 
ATOM 2040 C C   . MET B 1 209 ? 194.466 177.626 164.205 1.00 51.23 ? 209 MET B C   1 
ATOM 2041 O O   . MET B 1 209 ? 194.327 177.466 162.990 1.00 56.05 ? 209 MET B O   1 
ATOM 2042 C CB  . MET B 1 209 ? 193.976 180.104 164.003 1.00 52.34 ? 209 MET B CB  1 
ATOM 2043 C CG  . MET B 1 209 ? 192.552 180.373 164.446 1.00 52.52 ? 209 MET B CG  1 
ATOM 2044 S SD  . MET B 1 209 ? 192.460 181.478 165.867 1.00 58.69 ? 209 MET B SD  1 
ATOM 2045 C CE  . MET B 1 209 ? 190.706 181.831 165.913 1.00 43.13 ? 209 MET B CE  1 
ATOM 2046 N N   . GLU B 1 210 ? 194.417 176.622 165.079 1.00 47.20 ? 210 GLU B N   1 
ATOM 2047 C CA  . GLU B 1 210 ? 194.284 175.233 164.660 1.00 50.27 ? 210 GLU B CA  1 
ATOM 2048 C C   . GLU B 1 210 ? 193.164 174.561 165.439 1.00 43.23 ? 210 GLU B C   1 
ATOM 2049 O O   . GLU B 1 210 ? 193.122 174.650 166.669 1.00 42.12 ? 210 GLU B O   1 
ATOM 2050 C CB  . GLU B 1 210 ? 195.596 174.466 164.859 1.00 48.50 ? 210 GLU B CB  1 
ATOM 2051 C CG  . GLU B 1 210 ? 196.626 174.714 163.773 1.00 51.76 ? 210 GLU B CG  1 
ATOM 2052 C CD  . GLU B 1 210 ? 197.499 173.502 163.518 1.00 53.42 ? 210 GLU B CD  1 
ATOM 2053 O OE1 . GLU B 1 210 ? 197.602 172.643 164.420 1.00 55.46 ? 210 GLU B OE1 1 
ATOM 2054 O OE2 . GLU B 1 210 ? 198.077 173.406 162.416 1.00 50.29 ? 210 GLU B OE2 1 
ATOM 2055 N N   . ARG B 1 211 ? 192.264 173.890 164.715 1.00 45.35 ? 211 ARG B N   1 
ATOM 2056 C CA  . ARG B 1 211 ? 191.173 173.121 165.318 1.00 46.47 ? 211 ARG B CA  1 
ATOM 2057 C C   . ARG B 1 211 ? 190.363 173.983 166.284 1.00 46.82 ? 211 ARG B C   1 
ATOM 2058 O O   . ARG B 1 211 ? 189.907 173.525 167.333 1.00 46.12 ? 211 ARG B O   1 
ATOM 2059 C CB  . ARG B 1 211 ? 191.713 171.870 166.014 1.00 47.45 ? 211 ARG B CB  1 
ATOM 2060 C CG  . ARG B 1 211 ? 190.820 170.641 165.915 1.00 45.59 ? 211 ARG B CG  1 
ATOM 2061 C CD  . ARG B 1 211 ? 191.532 169.418 166.479 1.00 45.05 ? 211 ARG B CD  1 
ATOM 2062 N NE  . ARG B 1 211 ? 190.625 168.532 167.197 1.00 48.98 ? 211 ARG B NE  1 
ATOM 2063 C CZ  . ARG B 1 211 ? 191.014 167.505 167.938 1.00 50.76 ? 211 ARG B CZ  1 
ATOM 2064 N NH1 . ARG B 1 211 ? 192.294 167.203 168.084 1.00 49.50 ? 211 ARG B NH1 1 
ATOM 2065 N NH2 . ARG B 1 211 ? 190.096 166.764 168.554 1.00 47.89 ? 211 ARG B NH2 1 
ATOM 2066 N N   . VAL B 1 212 ? 190.171 175.250 165.912 1.00 48.66 ? 212 VAL B N   1 
ATOM 2067 C CA  . VAL B 1 212 ? 189.602 176.235 166.827 1.00 45.24 ? 212 VAL B CA  1 
ATOM 2068 C C   . VAL B 1 212 ? 188.101 176.036 166.997 1.00 46.06 ? 212 VAL B C   1 
ATOM 2069 O O   . VAL B 1 212 ? 187.581 176.113 168.113 1.00 51.41 ? 212 VAL B O   1 
ATOM 2070 C CB  . VAL B 1 212 ? 189.939 177.658 166.350 1.00 45.29 ? 212 VAL B CB  1 
ATOM 2071 C CG1 . VAL B 1 212 ? 189.120 178.684 167.114 1.00 45.67 ? 212 VAL B CG1 1 
ATOM 2072 C CG2 . VAL B 1 212 ? 191.412 177.921 166.548 1.00 47.61 ? 212 VAL B CG2 1 
ATOM 2073 N N   . VAL B 1 213 ? 187.377 175.837 165.898 1.00 40.84 ? 213 VAL B N   1 
ATOM 2074 C CA  . VAL B 1 213 ? 185.965 175.467 165.934 1.00 41.21 ? 213 VAL B CA  1 
ATOM 2075 C C   . VAL B 1 213 ? 185.808 174.236 165.053 1.00 47.58 ? 213 VAL B C   1 
ATOM 2076 O O   . VAL B 1 213 ? 186.030 174.303 163.839 1.00 48.73 ? 213 VAL B O   1 
ATOM 2077 C CB  . VAL B 1 213 ? 185.052 176.612 165.467 1.00 44.20 ? 213 VAL B CB  1 
ATOM 2078 C CG1 . VAL B 1 213 ? 183.593 176.258 165.703 1.00 41.51 ? 213 VAL B CG1 1 
ATOM 2079 C CG2 . VAL B 1 213 ? 185.406 177.910 166.180 1.00 44.98 ? 213 VAL B CG2 1 
ATOM 2080 N N   . GLU B 1 214 ? 185.381 173.124 165.644 1.00 49.20 ? 214 GLU B N   1 
ATOM 2081 C CA  . GLU B 1 214 ? 185.198 171.913 164.851 1.00 43.81 ? 214 GLU B CA  1 
ATOM 2082 C C   . GLU B 1 214 ? 183.784 171.818 164.300 1.00 42.04 ? 214 GLU B C   1 
ATOM 2083 O O   . GLU B 1 214 ? 183.602 171.446 163.138 1.00 48.73 ? 214 GLU B O   1 
ATOM 2084 C CB  . GLU B 1 214 ? 185.534 170.664 165.672 1.00 47.54 ? 214 GLU B CB  1 
ATOM 2085 C CG  . GLU B 1 214 ? 187.018 170.358 165.789 1.00 44.93 ? 214 GLU B CG  1 
ATOM 2086 C CD  . GLU B 1 214 ? 187.283 169.065 166.533 1.00 49.26 ? 214 GLU B CD  1 
ATOM 2087 O OE1 . GLU B 1 214 ? 186.431 168.667 167.358 1.00 50.88 ? 214 GLU B OE1 1 
ATOM 2088 O OE2 . GLU B 1 214 ? 188.342 168.445 166.303 1.00 51.10 ? 214 GLU B OE2 1 
ATOM 2089 N N   . GLN B 1 215 ? 182.778 172.145 165.106 1.00 37.13 ? 215 GLN B N   1 
ATOM 2090 C CA  . GLN B 1 215 ? 181.394 172.152 164.660 1.00 36.66 ? 215 GLN B CA  1 
ATOM 2091 C C   . GLN B 1 215 ? 180.674 173.350 165.257 1.00 42.88 ? 215 GLN B C   1 
ATOM 2092 O O   . GLN B 1 215 ? 181.010 173.812 166.350 1.00 43.51 ? 215 GLN B O   1 
ATOM 2093 C CB  . GLN B 1 215 ? 180.681 170.852 165.057 1.00 40.01 ? 215 GLN B CB  1 
ATOM 2094 C CG  . GLN B 1 215 ? 180.983 169.682 164.141 1.00 38.49 ? 215 GLN B CG  1 
ATOM 2095 C CD  . GLN B 1 215 ? 182.261 168.961 164.518 1.00 43.54 ? 215 GLN B CD  1 
ATOM 2096 O OE1 . GLN B 1 215 ? 182.596 168.838 165.696 1.00 44.42 ? 215 GLN B OE1 1 
ATOM 2097 N NE2 . GLN B 1 215 ? 182.992 168.498 163.514 1.00 37.51 ? 215 GLN B NE2 1 
ATOM 2098 N N   . MET B 1 216 ? 179.676 173.845 164.530 1.00 48.32 ? 216 MET B N   1 
ATOM 2099 C CA  . MET B 1 216 ? 178.881 174.975 164.991 1.00 43.39 ? 216 MET B CA  1 
ATOM 2100 C C   . MET B 1 216 ? 177.558 174.967 164.243 1.00 40.31 ? 216 MET B C   1 
ATOM 2101 O O   . MET B 1 216 ? 177.533 174.771 163.027 1.00 42.89 ? 216 MET B O   1 
ATOM 2102 C CB  . MET B 1 216 ? 179.623 176.302 164.791 1.00 41.54 ? 216 MET B CB  1 
ATOM 2103 C CG  . MET B 1 216 ? 179.005 177.476 165.532 1.00 44.60 ? 216 MET B CG  1 
ATOM 2104 S SD  . MET B 1 216 ? 180.136 178.866 165.740 1.00 53.13 ? 216 MET B SD  1 
ATOM 2105 C CE  . MET B 1 216 ? 181.157 178.708 164.278 1.00 49.74 ? 216 MET B CE  1 
ATOM 2106 N N   . CYS B 1 217 ? 176.467 175.185 164.981 1.00 43.52 ? 217 CYS B N   1 
ATOM 2107 C CA  . CYS B 1 217 ? 175.118 175.245 164.410 1.00 39.89 ? 217 CYS B CA  1 
ATOM 2108 C C   . CYS B 1 217 ? 174.778 173.988 163.614 1.00 39.07 ? 217 CYS B C   1 
ATOM 2109 O O   . CYS B 1 217 ? 174.170 174.054 162.544 1.00 39.65 ? 217 CYS B O   1 
ATOM 2110 C CB  . CYS B 1 217 ? 174.953 176.493 163.542 1.00 39.68 ? 217 CYS B CB  1 
ATOM 2111 S SG  . CYS B 1 217 ? 175.682 177.981 164.246 1.00 56.99 ? 217 CYS B SG  1 
ATOM 2112 N N   . ILE B 1 218 ? 175.166 172.830 164.143 1.00 39.60 ? 218 ILE B N   1 
ATOM 2113 C CA  . ILE B 1 218 ? 174.909 171.550 163.482 1.00 40.89 ? 218 ILE B CA  1 
ATOM 2114 C C   . ILE B 1 218 ? 173.533 171.088 163.950 1.00 37.93 ? 218 ILE B C   1 
ATOM 2115 O O   . ILE B 1 218 ? 173.382 170.458 164.997 1.00 43.77 ? 218 ILE B O   1 
ATOM 2116 C CB  . ILE B 1 218 ? 175.998 170.521 163.775 1.00 38.54 ? 218 ILE B CB  1 
ATOM 2117 C CG1 . ILE B 1 218 ? 177.383 171.117 163.516 1.00 40.26 ? 218 ILE B CG1 1 
ATOM 2118 C CG2 . ILE B 1 218 ? 175.787 169.272 162.937 1.00 33.45 ? 218 ILE B CG2 1 
ATOM 2119 C CD1 . ILE B 1 218 ? 177.552 171.715 162.146 1.00 36.50 ? 218 ILE B CD1 1 
ATOM 2120 N N   . THR B 1 219 ? 172.512 171.411 163.160 1.00 27.02 ? 219 THR B N   1 
ATOM 2121 C CA  . THR B 1 219 ? 171.145 170.965 163.429 1.00 30.50 ? 219 THR B CA  1 
ATOM 2122 C C   . THR B 1 219 ? 170.954 169.633 162.717 1.00 34.48 ? 219 THR B C   1 
ATOM 2123 O O   . THR B 1 219 ? 170.478 169.570 161.583 1.00 35.24 ? 219 THR B O   1 
ATOM 2124 C CB  . THR B 1 219 ? 170.131 172.005 162.970 1.00 33.52 ? 219 THR B CB  1 
ATOM 2125 O OG1 . THR B 1 219 ? 170.496 173.292 163.485 1.00 36.53 ? 219 THR B OG1 1 
ATOM 2126 C CG2 . THR B 1 219 ? 168.740 171.644 163.468 1.00 32.51 ? 219 THR B CG2 1 
ATOM 2127 N N   . GLN B 1 220 ? 171.335 168.554 163.394 1.00 27.57 ? 220 GLN B N   1 
ATOM 2128 C CA  . GLN B 1 220 ? 171.320 167.217 162.819 1.00 24.68 ? 220 GLN B CA  1 
ATOM 2129 C C   . GLN B 1 220 ? 170.301 166.352 163.545 1.00 19.70 ? 220 GLN B C   1 
ATOM 2130 O O   . GLN B 1 220 ? 170.342 166.235 164.774 1.00 31.43 ? 220 GLN B O   1 
ATOM 2131 C CB  . GLN B 1 220 ? 172.708 166.576 162.898 1.00 26.51 ? 220 GLN B CB  1 
ATOM 2132 C CG  . GLN B 1 220 ? 172.923 165.436 161.922 1.00 31.04 ? 220 GLN B CG  1 
ATOM 2133 C CD  . GLN B 1 220 ? 174.391 165.129 161.702 1.00 32.04 ? 220 GLN B CD  1 
ATOM 2134 O OE1 . GLN B 1 220 ? 175.093 164.712 162.622 1.00 34.98 ? 220 GLN B OE1 1 
ATOM 2135 N NE2 . GLN B 1 220 ? 174.861 165.334 160.478 1.00 27.30 ? 220 GLN B NE2 1 
ATOM 2136 N N   . TYR B 1 221 ? 169.391 165.749 162.785 1.00 18.91 ? 221 TYR B N   1 
ATOM 2137 C CA  . TYR B 1 221 ? 168.418 164.805 163.318 1.00 26.03 ? 221 TYR B CA  1 
ATOM 2138 C C   . TYR B 1 221 ? 168.840 163.406 162.894 1.00 28.67 ? 221 TYR B C   1 
ATOM 2139 O O   . TYR B 1 221 ? 168.987 163.134 161.697 1.00 27.26 ? 221 TYR B O   1 
ATOM 2140 C CB  . TYR B 1 221 ? 167.003 165.119 162.827 1.00 31.08 ? 221 TYR B CB  1 
ATOM 2141 C CG  . TYR B 1 221 ? 166.528 166.523 163.132 1.00 34.35 ? 221 TYR B CG  1 
ATOM 2142 C CD1 . TYR B 1 221 ? 167.116 167.279 164.138 1.00 32.87 ? 221 TYR B CD1 1 
ATOM 2143 C CD2 . TYR B 1 221 ? 165.483 167.090 162.416 1.00 32.90 ? 221 TYR B CD2 1 
ATOM 2144 C CE1 . TYR B 1 221 ? 166.686 168.561 164.415 1.00 32.11 ? 221 TYR B CE1 1 
ATOM 2145 C CE2 . TYR B 1 221 ? 165.042 168.372 162.687 1.00 31.97 ? 221 TYR B CE2 1 
ATOM 2146 C CZ  . TYR B 1 221 ? 165.647 169.102 163.688 1.00 34.85 ? 221 TYR B CZ  1 
ATOM 2147 O OH  . TYR B 1 221 ? 165.213 170.378 163.963 1.00 40.38 ? 221 TYR B OH  1 
ATOM 2148 N N   . GLN B 1 222 ? 169.036 162.525 163.871 1.00 28.93 ? 222 GLN B N   1 
ATOM 2149 C CA  . GLN B 1 222 ? 169.565 161.189 163.634 1.00 19.01 ? 222 GLN B CA  1 
ATOM 2150 C C   . GLN B 1 222 ? 168.551 160.147 164.079 1.00 20.66 ? 222 GLN B C   1 
ATOM 2151 O O   . GLN B 1 222 ? 167.988 160.250 165.173 1.00 30.48 ? 222 GLN B O   1 
ATOM 2152 C CB  . GLN B 1 222 ? 170.888 160.988 164.374 1.00 23.57 ? 222 GLN B CB  1 
ATOM 2153 C CG  . GLN B 1 222 ? 172.033 161.838 163.858 1.00 31.19 ? 222 GLN B CG  1 
ATOM 2154 C CD  . GLN B 1 222 ? 173.336 161.552 164.578 1.00 31.12 ? 222 GLN B CD  1 
ATOM 2155 O OE1 . GLN B 1 222 ? 173.367 160.795 165.548 1.00 25.97 ? 222 GLN B OE1 1 
ATOM 2156 N NE2 . GLN B 1 222 ? 174.418 162.159 164.109 1.00 30.01 ? 222 GLN B NE2 1 
ATOM 2157 N N   . ARG B 1 223 ? 168.325 159.147 163.229 1.00 26.00 ? 223 ARG B N   1 
ATOM 2158 C CA  . ARG B 1 223 ? 167.460 158.013 163.558 1.00 34.43 ? 223 ARG B CA  1 
ATOM 2159 C C   . ARG B 1 223 ? 168.134 156.758 163.014 1.00 30.07 ? 223 ARG B C   1 
ATOM 2160 O O   . ARG B 1 223 ? 168.116 156.516 161.803 1.00 23.53 ? 223 ARG B O   1 
ATOM 2161 C CB  . ARG B 1 223 ? 166.060 158.187 162.983 1.00 31.74 ? 223 ARG B CB  1 
ATOM 2162 C CG  . ARG B 1 223 ? 165.182 156.955 163.125 1.00 30.02 ? 223 ARG B CG  1 
ATOM 2163 C CD  . ARG B 1 223 ? 163.823 157.167 162.485 1.00 34.03 ? 223 ARG B CD  1 
ATOM 2164 N NE  . ARG B 1 223 ? 162.911 157.886 163.367 1.00 41.45 ? 223 ARG B NE  1 
ATOM 2165 C CZ  . ARG B 1 223 ? 162.135 157.307 164.273 1.00 40.46 ? 223 ARG B CZ  1 
ATOM 2166 N NH1 . ARG B 1 223 ? 162.134 155.996 164.446 1.00 32.84 ? 223 ARG B NH1 1 
ATOM 2167 N NH2 . ARG B 1 223 ? 161.340 158.064 165.024 1.00 38.48 ? 223 ARG B NH2 1 
ATOM 2168 N N   . GLU B 1 224 ? 168.728 155.970 163.913 1.00 37.17 ? 224 GLU B N   1 
ATOM 2169 C CA  . GLU B 1 224 ? 169.460 154.756 163.545 1.00 35.63 ? 224 GLU B CA  1 
ATOM 2170 C C   . GLU B 1 224 ? 170.554 155.061 162.524 1.00 31.88 ? 224 GLU B C   1 
ATOM 2171 O O   . GLU B 1 224 ? 170.818 154.274 161.614 1.00 30.40 ? 224 GLU B O   1 
ATOM 2172 C CB  . GLU B 1 224 ? 168.514 153.674 163.022 1.00 36.99 ? 224 GLU B CB  1 
ATOM 2173 C CG  . GLU B 1 224 ? 167.274 153.469 163.875 1.00 38.56 ? 224 GLU B CG  1 
ATOM 2174 C CD  . GLU B 1 224 ? 166.143 152.813 163.109 1.00 39.04 ? 224 GLU B CD  1 
ATOM 2175 O OE1 . GLU B 1 224 ? 166.426 151.953 162.249 1.00 44.99 ? 224 GLU B OE1 1 
ATOM 2176 O OE2 . GLU B 1 224 ? 164.971 153.159 163.365 1.00 37.17 ? 224 GLU B OE2 1 
ATOM 2177 N N   . SER B 1 225 ? 171.200 156.212 162.683 1.00 30.11 ? 225 SER B N   1 
ATOM 2178 C CA  . SER B 1 225 ? 172.183 156.706 161.735 1.00 28.70 ? 225 SER B CA  1 
ATOM 2179 C C   . SER B 1 225 ? 173.516 156.944 162.433 1.00 29.20 ? 225 SER B C   1 
ATOM 2180 O O   . SER B 1 225 ? 173.633 156.843 163.657 1.00 39.53 ? 225 SER B O   1 
ATOM 2181 C CB  . SER B 1 225 ? 171.695 157.995 161.064 1.00 30.27 ? 225 SER B CB  1 
ATOM 2182 O OG  . SER B 1 225 ? 170.495 157.771 160.345 1.00 37.64 ? 225 SER B OG  1 
ATOM 2183 N N   . GLN B 1 226 ? 174.532 157.258 161.633 1.00 33.40 ? 226 GLN B N   1 
ATOM 2184 C CA  . GLN B 1 226 ? 175.874 157.494 162.145 1.00 32.84 ? 226 GLN B CA  1 
ATOM 2185 C C   . GLN B 1 226 ? 176.461 158.732 161.487 1.00 32.49 ? 226 GLN B C   1 
ATOM 2186 O O   . GLN B 1 226 ? 176.288 158.947 160.284 1.00 32.50 ? 226 GLN B O   1 
ATOM 2187 C CB  . GLN B 1 226 ? 176.788 156.286 161.899 1.00 20.31 ? 226 GLN B CB  1 
ATOM 2188 C CG  . GLN B 1 226 ? 176.483 155.085 162.778 1.00 24.05 ? 226 GLN B CG  1 
ATOM 2189 C CD  . GLN B 1 226 ? 175.349 154.237 162.235 1.00 30.51 ? 226 GLN B CD  1 
ATOM 2190 O OE1 . GLN B 1 226 ? 175.200 154.082 161.023 1.00 31.21 ? 226 GLN B OE1 1 
ATOM 2191 N NE2 . GLN B 1 226 ? 174.539 153.689 163.132 1.00 34.29 ? 226 GLN B NE2 1 
ATOM 2192 N N   . ALA B 1 227 ? 177.153 159.543 162.284 1.00 24.60 ? 227 ALA B N   1 
ATOM 2193 C CA  . ALA B 1 227 ? 177.854 160.722 161.794 1.00 21.13 ? 227 ALA B CA  1 
ATOM 2194 C C   . ALA B 1 227 ? 179.271 160.711 162.345 1.00 27.62 ? 227 ALA B C   1 
ATOM 2195 O O   . ALA B 1 227 ? 179.468 160.559 163.555 1.00 26.65 ? 227 ALA B O   1 
ATOM 2196 C CB  . ALA B 1 227 ? 177.134 162.010 162.198 1.00 25.28 ? 227 ALA B CB  1 
ATOM 2197 N N   . TYR B 1 228 ? 180.251 160.873 161.460 1.00 37.96 ? 228 TYR B N   1 
ATOM 2198 C CA  . TYR B 1 228 ? 181.661 160.846 161.828 1.00 32.61 ? 228 TYR B CA  1 
ATOM 2199 C C   . TYR B 1 228 ? 182.294 162.175 161.444 1.00 28.12 ? 228 TYR B C   1 
ATOM 2200 O O   . TYR B 1 228 ? 182.249 162.573 160.275 1.00 41.58 ? 228 TYR B O   1 
ATOM 2201 C CB  . TYR B 1 228 ? 182.384 159.684 161.145 1.00 24.71 ? 228 TYR B CB  1 
ATOM 2202 C CG  . TYR B 1 228 ? 181.901 158.322 161.586 1.00 26.42 ? 228 TYR B CG  1 
ATOM 2203 C CD1 . TYR B 1 228 ? 180.762 157.754 161.030 1.00 24.15 ? 228 TYR B CD1 1 
ATOM 2204 C CD2 . TYR B 1 228 ? 182.583 157.604 162.559 1.00 29.54 ? 228 TYR B CD2 1 
ATOM 2205 C CE1 . TYR B 1 228 ? 180.317 156.510 161.431 1.00 30.89 ? 228 TYR B CE1 1 
ATOM 2206 C CE2 . TYR B 1 228 ? 182.146 156.359 162.965 1.00 32.18 ? 228 TYR B CE2 1 
ATOM 2207 C CZ  . TYR B 1 228 ? 181.011 155.817 162.399 1.00 30.31 ? 228 TYR B CZ  1 
ATOM 2208 O OH  . TYR B 1 228 ? 180.569 154.577 162.800 1.00 33.57 ? 228 TYR B OH  1 
ATOM 2209 N N   . TYR B 1 229 ? 182.885 162.852 162.423 1.00 21.12 ? 229 TYR B N   1 
ATOM 2210 C CA  . TYR B 1 229 ? 183.506 164.149 162.191 1.00 17.80 ? 229 TYR B CA  1 
ATOM 2211 C C   . TYR B 1 229 ? 185.016 164.076 162.379 1.00 24.83 ? 229 TYR B C   1 
ATOM 2212 O O   . TYR B 1 229 ? 185.500 163.684 163.440 1.00 35.68 ? 229 TYR B O   1 
ATOM 2213 C CB  . TYR B 1 229 ? 182.908 165.203 163.125 1.00 29.15 ? 229 TYR B CB  1 
ATOM 2214 C CG  . TYR B 1 229 ? 181.415 165.388 162.968 1.00 32.70 ? 229 TYR B CG  1 
ATOM 2215 C CD1 . TYR B 1 229 ? 180.902 166.316 162.070 1.00 25.81 ? 229 TYR B CD1 1 
ATOM 2216 C CD2 . TYR B 1 229 ? 180.519 164.639 163.718 1.00 26.63 ? 229 TYR B CD2 1 
ATOM 2217 C CE1 . TYR B 1 229 ? 179.540 166.490 161.923 1.00 23.56 ? 229 TYR B CE1 1 
ATOM 2218 C CE2 . TYR B 1 229 ? 179.155 164.805 163.578 1.00 23.50 ? 229 TYR B CE2 1 
ATOM 2219 C CZ  . TYR B 1 229 ? 178.671 165.732 162.680 1.00 31.98 ? 229 TYR B CZ  1 
ATOM 2220 O OH  . TYR B 1 229 ? 177.314 165.901 162.536 1.00 37.18 ? 229 TYR B OH  1 
ATOM 2221 N N   . GLY C 1 92  ? 108.498 165.889 148.253 1.00 20.68 ? 92  GLY C N   1 
ATOM 2222 C CA  . GLY C 1 92  ? 109.358 164.772 148.597 1.00 21.41 ? 92  GLY C CA  1 
ATOM 2223 C C   . GLY C 1 92  ? 110.536 164.615 147.656 1.00 23.11 ? 92  GLY C C   1 
ATOM 2224 O O   . GLY C 1 92  ? 110.767 163.537 147.110 1.00 20.48 ? 92  GLY C O   1 
ATOM 2225 N N   . TRP C 1 93  ? 111.285 165.698 147.469 1.00 18.12 ? 93  TRP C N   1 
ATOM 2226 C CA  . TRP C 1 93  ? 112.438 165.694 146.587 1.00 8.04  ? 93  TRP C CA  1 
ATOM 2227 C C   . TRP C 1 93  ? 113.678 165.218 147.341 1.00 13.07 ? 93  TRP C C   1 
ATOM 2228 O O   . TRP C 1 93  ? 113.629 164.881 148.526 1.00 20.48 ? 93  TRP C O   1 
ATOM 2229 C CB  . TRP C 1 93  ? 112.653 167.082 145.988 1.00 14.88 ? 93  TRP C CB  1 
ATOM 2230 C CG  . TRP C 1 93  ? 112.764 168.168 147.015 1.00 13.87 ? 93  TRP C CG  1 
ATOM 2231 C CD1 . TRP C 1 93  ? 111.745 168.911 147.533 1.00 14.01 ? 93  TRP C CD1 1 
ATOM 2232 C CD2 . TRP C 1 93  ? 113.963 168.632 147.648 1.00 18.34 ? 93  TRP C CD2 1 
ATOM 2233 N NE1 . TRP C 1 93  ? 112.234 169.810 148.450 1.00 12.85 ? 93  TRP C NE1 1 
ATOM 2234 C CE2 . TRP C 1 93  ? 113.593 169.659 148.538 1.00 14.76 ? 93  TRP C CE2 1 
ATOM 2235 C CE3 . TRP C 1 93  ? 115.312 168.280 147.549 1.00 13.41 ? 93  TRP C CE3 1 
ATOM 2236 C CZ2 . TRP C 1 93  ? 114.521 170.334 149.326 1.00 16.24 ? 93  TRP C CZ2 1 
ATOM 2237 C CZ3 . TRP C 1 93  ? 116.232 168.953 148.330 1.00 16.46 ? 93  TRP C CZ3 1 
ATOM 2238 C CH2 . TRP C 1 93  ? 115.833 169.969 149.206 1.00 14.58 ? 93  TRP C CH2 1 
ATOM 2239 N N   . GLY C 1 94  ? 114.810 165.190 146.642 1.00 12.32 ? 94  GLY C N   1 
ATOM 2240 C CA  . GLY C 1 94  ? 116.050 164.755 147.249 1.00 20.82 ? 94  GLY C CA  1 
ATOM 2241 C C   . GLY C 1 94  ? 117.286 165.236 146.519 1.00 1.63  ? 94  GLY C C   1 
ATOM 2242 O O   . GLY C 1 94  ? 117.376 165.129 145.293 1.00 6.23  ? 94  GLY C O   1 
ATOM 2243 N N   . GLN C 1 95  ? 118.250 165.766 147.264 1.00 3.89  ? 95  GLN C N   1 
ATOM 2244 C CA  . GLN C 1 95  ? 119.520 166.216 146.713 1.00 7.12  ? 95  GLN C CA  1 
ATOM 2245 C C   . GLN C 1 95  ? 120.627 165.291 147.198 1.00 14.08 ? 95  GLN C C   1 
ATOM 2246 O O   . GLN C 1 95  ? 120.771 165.069 148.405 1.00 11.67 ? 95  GLN C O   1 
ATOM 2247 C CB  . GLN C 1 95  ? 119.815 167.662 147.119 1.00 20.06 ? 95  GLN C CB  1 
ATOM 2248 C CG  . GLN C 1 95  ? 119.159 168.703 146.227 1.00 12.05 ? 95  GLN C CG  1 
ATOM 2249 C CD  . GLN C 1 95  ? 119.410 170.120 146.704 1.00 13.50 ? 95  GLN C CD  1 
ATOM 2250 O OE1 . GLN C 1 95  ? 119.147 170.453 147.860 1.00 21.18 ? 95  GLN C OE1 1 
ATOM 2251 N NE2 . GLN C 1 95  ? 119.919 170.963 145.814 1.00 9.13  ? 95  GLN C NE2 1 
ATOM 2252 N N   . GLY C 1 96  ? 121.400 164.754 146.258 1.00 19.23 ? 96  GLY C N   1 
ATOM 2253 C CA  . GLY C 1 96  ? 122.451 163.825 146.617 1.00 15.72 ? 96  GLY C CA  1 
ATOM 2254 C C   . GLY C 1 96  ? 123.558 164.491 147.413 1.00 11.39 ? 96  GLY C C   1 
ATOM 2255 O O   . GLY C 1 96  ? 123.836 165.681 147.271 1.00 15.84 ? 96  GLY C O   1 
ATOM 2256 N N   . GLY C 1 97  ? 124.195 163.698 148.272 1.00 26.07 ? 97  GLY C N   1 
ATOM 2257 C CA  . GLY C 1 97  ? 125.278 164.216 149.083 1.00 21.87 ? 97  GLY C CA  1 
ATOM 2258 C C   . GLY C 1 97  ? 126.467 164.639 148.241 1.00 19.44 ? 97  GLY C C   1 
ATOM 2259 O O   . GLY C 1 97  ? 126.787 164.035 147.217 1.00 24.60 ? 97  GLY C O   1 
ATOM 2260 N N   . THR C 1 98  ? 127.131 165.698 148.687 1.00 16.16 ? 98  THR C N   1 
ATOM 2261 C CA  . THR C 1 98  ? 128.261 166.272 147.971 1.00 20.45 ? 98  THR C CA  1 
ATOM 2262 C C   . THR C 1 98  ? 129.559 165.815 148.623 1.00 28.17 ? 98  THR C C   1 
ATOM 2263 O O   . THR C 1 98  ? 129.798 166.094 149.803 1.00 24.95 ? 98  THR C O   1 
ATOM 2264 C CB  . THR C 1 98  ? 128.184 167.797 147.954 1.00 27.73 ? 98  THR C CB  1 
ATOM 2265 O OG1 . THR C 1 98  ? 127.014 168.212 147.237 1.00 34.87 ? 98  THR C OG1 1 
ATOM 2266 C CG2 . THR C 1 98  ? 129.414 168.377 147.280 1.00 25.45 ? 98  THR C CG2 1 
ATOM 2267 N N   . HIS C 1 99  ? 130.390 165.115 147.856 1.00 29.53 ? 99  HIS C N   1 
ATOM 2268 C CA  . HIS C 1 99  ? 131.735 164.725 148.273 1.00 21.77 ? 99  HIS C CA  1 
ATOM 2269 C C   . HIS C 1 99  ? 132.702 165.415 147.320 1.00 18.56 ? 99  HIS C C   1 
ATOM 2270 O O   . HIS C 1 99  ? 133.156 164.828 146.336 1.00 27.14 ? 99  HIS C O   1 
ATOM 2271 C CB  . HIS C 1 99  ? 131.905 163.200 148.263 1.00 23.79 ? 99  HIS C CB  1 
ATOM 2272 C CG  . HIS C 1 99  ? 130.805 162.464 148.964 1.00 31.37 ? 99  HIS C CG  1 
ATOM 2273 N ND1 . HIS C 1 99  ? 129.537 162.344 148.440 1.00 26.06 ? 99  HIS C ND1 1 
ATOM 2274 C CD2 . HIS C 1 99  ? 130.786 161.808 150.148 1.00 33.68 ? 99  HIS C CD2 1 
ATOM 2275 C CE1 . HIS C 1 99  ? 128.783 161.647 149.271 1.00 25.46 ? 99  HIS C CE1 1 
ATOM 2276 N NE2 . HIS C 1 99  ? 129.517 161.310 150.316 1.00 32.69 ? 99  HIS C NE2 1 
ATOM 2277 N N   . SER C 1 100 ? 133.028 166.667 147.627 1.00 24.22 ? 100 SER C N   1 
ATOM 2278 C CA  . SER C 1 100 ? 133.798 167.519 146.734 1.00 20.38 ? 100 SER C CA  1 
ATOM 2279 C C   . SER C 1 100 ? 135.020 168.057 147.458 1.00 22.99 ? 100 SER C C   1 
ATOM 2280 O O   . SER C 1 100 ? 134.952 168.397 148.641 1.00 27.23 ? 100 SER C O   1 
ATOM 2281 C CB  . SER C 1 100 ? 132.945 168.680 146.210 1.00 26.48 ? 100 SER C CB  1 
ATOM 2282 O OG  . SER C 1 100 ? 131.980 168.223 145.279 1.00 26.03 ? 100 SER C OG  1 
ATOM 2283 N N   . GLN C 1 101 ? 136.136 168.137 146.742 1.00 21.79 ? 101 GLN C N   1 
ATOM 2284 C CA  . GLN C 1 101 ? 137.389 168.611 147.313 1.00 20.71 ? 101 GLN C CA  1 
ATOM 2285 C C   . GLN C 1 101 ? 137.946 169.741 146.464 1.00 10.68 ? 101 GLN C C   1 
ATOM 2286 O O   . GLN C 1 101 ? 138.126 169.579 145.255 1.00 30.42 ? 101 GLN C O   1 
ATOM 2287 C CB  . GLN C 1 101 ? 138.415 167.476 147.411 1.00 12.44 ? 101 GLN C CB  1 
ATOM 2288 C CG  . GLN C 1 101 ? 138.061 166.405 148.429 1.00 10.43 ? 101 GLN C CG  1 
ATOM 2289 C CD  . GLN C 1 101 ? 137.123 165.355 147.869 1.00 15.80 ? 101 GLN C CD  1 
ATOM 2290 O OE1 . GLN C 1 101 ? 137.177 165.028 146.683 1.00 20.91 ? 101 GLN C OE1 1 
ATOM 2291 N NE2 . GLN C 1 101 ? 136.256 164.820 148.719 1.00 23.88 ? 101 GLN C NE2 1 
ATOM 2292 N N   . TRP C 1 102 ? 138.222 170.882 147.098 1.00 6.30  ? 102 TRP C N   1 
ATOM 2293 C CA  . TRP C 1 102 ? 138.863 171.976 146.376 1.00 1.57  ? 102 TRP C CA  1 
ATOM 2294 C C   . TRP C 1 102 ? 140.260 171.593 145.909 1.00 18.29 ? 102 TRP C C   1 
ATOM 2295 O O   . TRP C 1 102 ? 140.751 172.130 144.909 1.00 18.74 ? 102 TRP C O   1 
ATOM 2296 C CB  . TRP C 1 102 ? 138.917 173.229 147.250 1.00 12.63 ? 102 TRP C CB  1 
ATOM 2297 C CG  . TRP C 1 102 ? 139.394 174.443 146.512 1.00 14.90 ? 102 TRP C CG  1 
ATOM 2298 C CD1 . TRP C 1 102 ? 140.604 175.056 146.640 1.00 13.41 ? 102 TRP C CD1 1 
ATOM 2299 C CD2 . TRP C 1 102 ? 138.670 175.185 145.524 1.00 11.77 ? 102 TRP C CD2 1 
ATOM 2300 N NE1 . TRP C 1 102 ? 140.678 176.137 145.796 1.00 9.17  ? 102 TRP C NE1 1 
ATOM 2301 C CE2 . TRP C 1 102 ? 139.504 176.237 145.099 1.00 4.61  ? 102 TRP C CE2 1 
ATOM 2302 C CE3 . TRP C 1 102 ? 137.397 175.062 144.959 1.00 14.49 ? 102 TRP C CE3 1 
ATOM 2303 C CZ2 . TRP C 1 102 ? 139.107 177.161 144.135 1.00 8.88  ? 102 TRP C CZ2 1 
ATOM 2304 C CZ3 . TRP C 1 102 ? 137.005 175.980 144.002 1.00 9.74  ? 102 TRP C CZ3 1 
ATOM 2305 C CH2 . TRP C 1 102 ? 137.857 177.015 143.601 1.00 9.87  ? 102 TRP C CH2 1 
ATOM 2306 N N   . ASN C 1 103 ? 140.910 170.670 146.612 1.00 29.15 ? 103 ASN C N   1 
ATOM 2307 C CA  . ASN C 1 103 ? 142.226 170.176 146.218 1.00 19.27 ? 103 ASN C CA  1 
ATOM 2308 C C   . ASN C 1 103 ? 142.380 168.776 146.794 1.00 23.02 ? 103 ASN C C   1 
ATOM 2309 O O   . ASN C 1 103 ? 142.427 168.610 148.016 1.00 20.73 ? 103 ASN C O   1 
ATOM 2310 C CB  . ASN C 1 103 ? 143.334 171.101 146.715 1.00 10.46 ? 103 ASN C CB  1 
ATOM 2311 C CG  . ASN C 1 103 ? 144.688 170.750 146.135 1.00 23.51 ? 103 ASN C CG  1 
ATOM 2312 O OD1 . ASN C 1 103 ? 144.788 170.276 145.004 1.00 13.51 ? 103 ASN C OD1 1 
ATOM 2313 N ND2 . ASN C 1 103 ? 145.741 170.985 146.908 1.00 25.90 ? 103 ASN C ND2 1 
ATOM 2314 N N   . LYS C 1 104 ? 142.456 167.774 145.919 1.00 14.47 ? 104 LYS C N   1 
ATOM 2315 C CA  . LYS C 1 104 ? 142.574 166.373 146.322 1.00 13.11 ? 104 LYS C CA  1 
ATOM 2316 C C   . LYS C 1 104 ? 143.759 165.744 145.603 1.00 21.71 ? 104 LYS C C   1 
ATOM 2317 O O   . LYS C 1 104 ? 143.586 164.985 144.639 1.00 26.40 ? 104 LYS C O   1 
ATOM 2318 C CB  . LYS C 1 104 ? 141.284 165.604 146.032 1.00 11.00 ? 104 LYS C CB  1 
ATOM 2319 C CG  . LYS C 1 104 ? 141.218 164.234 146.686 1.00 14.11 ? 104 LYS C CG  1 
ATOM 2320 C CD  . LYS C 1 104 ? 140.032 163.434 146.177 1.00 14.28 ? 104 LYS C CD  1 
ATOM 2321 C CE  . LYS C 1 104 ? 140.238 161.945 146.394 1.00 20.12 ? 104 LYS C CE  1 
ATOM 2322 N NZ  . LYS C 1 104 ? 140.308 161.596 147.839 1.00 22.75 ? 104 LYS C NZ  1 
ATOM 2323 N N   . PRO C 1 105 ? 144.983 166.042 146.041 1.00 27.36 ? 105 PRO C N   1 
ATOM 2324 C CA  . PRO C 1 105 ? 146.154 165.380 145.455 1.00 24.88 ? 105 PRO C CA  1 
ATOM 2325 C C   . PRO C 1 105 ? 146.490 164.080 146.168 1.00 27.76 ? 105 PRO C C   1 
ATOM 2326 O O   . PRO C 1 105 ? 146.632 164.057 147.394 1.00 24.01 ? 105 PRO C O   1 
ATOM 2327 C CB  . PRO C 1 105 ? 147.267 166.422 145.621 1.00 20.61 ? 105 PRO C CB  1 
ATOM 2328 C CG  . PRO C 1 105 ? 146.795 167.341 146.731 1.00 27.07 ? 105 PRO C CG  1 
ATOM 2329 C CD  . PRO C 1 105 ? 145.367 167.014 147.077 1.00 26.96 ? 105 PRO C CD  1 
ATOM 2330 N N   . SER C 1 106 ? 146.622 162.995 145.413 1.00 27.43 ? 106 SER C N   1 
ATOM 2331 C CA  . SER C 1 106 ? 146.902 161.681 145.974 1.00 26.39 ? 106 SER C CA  1 
ATOM 2332 C C   . SER C 1 106 ? 148.376 161.349 145.796 1.00 37.67 ? 106 SER C C   1 
ATOM 2333 O O   . SER C 1 106 ? 148.892 161.379 144.675 1.00 36.63 ? 106 SER C O   1 
ATOM 2334 C CB  . SER C 1 106 ? 146.034 160.611 145.312 1.00 30.29 ? 106 SER C CB  1 
ATOM 2335 O OG  . SER C 1 106 ? 146.131 159.377 146.003 1.00 39.13 ? 106 SER C OG  1 
ATOM 2336 N N   . LYS C 1 107 ? 149.043 161.029 146.902 1.00 36.62 ? 107 LYS C N   1 
ATOM 2337 C CA  . LYS C 1 107 ? 150.456 160.670 146.916 1.00 32.08 ? 107 LYS C CA  1 
ATOM 2338 C C   . LYS C 1 107 ? 151.345 161.661 146.156 1.00 32.37 ? 107 LYS C C   1 
ATOM 2339 O O   . LYS C 1 107 ? 152.016 161.284 145.190 1.00 34.11 ? 107 LYS C O   1 
ATOM 2340 C CB  . LYS C 1 107 ? 150.650 159.259 146.377 1.00 30.25 ? 107 LYS C CB  1 
ATOM 2341 C CG  . LYS C 1 107 ? 149.903 158.187 147.152 1.00 33.37 ? 107 LYS C CG  1 
ATOM 2342 C CD  . LYS C 1 107 ? 149.780 156.910 146.339 1.00 33.55 ? 107 LYS C CD  1 
ATOM 2343 C CE  . LYS C 1 107 ? 148.894 155.892 147.037 1.00 31.41 ? 107 LYS C CE  1 
ATOM 2344 N NZ  . LYS C 1 107 ? 148.767 154.636 146.248 1.00 34.53 ? 107 LYS C NZ  1 
ATOM 2345 N N   . PRO C 1 108 ? 151.373 162.936 146.565 1.00 30.95 ? 108 PRO C N   1 
ATOM 2346 C CA  . PRO C 1 108 ? 152.286 163.895 145.928 1.00 28.77 ? 108 PRO C CA  1 
ATOM 2347 C C   . PRO C 1 108 ? 153.700 163.763 146.471 1.00 36.78 ? 108 PRO C C   1 
ATOM 2348 O O   . PRO C 1 108 ? 153.999 164.191 147.591 1.00 43.26 ? 108 PRO C O   1 
ATOM 2349 C CB  . PRO C 1 108 ? 151.655 165.251 146.274 1.00 27.38 ? 108 PRO C CB  1 
ATOM 2350 C CG  . PRO C 1 108 ? 151.007 165.027 147.585 1.00 28.40 ? 108 PRO C CG  1 
ATOM 2351 C CD  . PRO C 1 108 ? 150.597 163.567 147.649 1.00 31.51 ? 108 PRO C CD  1 
ATOM 2352 N N   . LYS C 1 109 ? 154.579 163.166 145.671 1.00 33.61 ? 109 LYS C N   1 
ATOM 2353 C CA  . LYS C 1 109 ? 155.989 163.017 146.014 1.00 28.35 ? 109 LYS C CA  1 
ATOM 2354 C C   . LYS C 1 109 ? 156.752 164.131 145.310 1.00 33.90 ? 109 LYS C C   1 
ATOM 2355 O O   . LYS C 1 109 ? 156.873 164.128 144.080 1.00 34.26 ? 109 LYS C O   1 
ATOM 2356 C CB  . LYS C 1 109 ? 156.508 161.641 145.607 1.00 23.60 ? 109 LYS C CB  1 
ATOM 2357 C CG  . LYS C 1 109 ? 155.960 160.502 146.452 1.00 31.99 ? 109 LYS C CG  1 
ATOM 2358 C CD  . LYS C 1 109 ? 156.446 159.153 145.950 1.00 35.40 ? 109 LYS C CD  1 
ATOM 2359 C CE  . LYS C 1 109 ? 155.886 158.018 146.791 1.00 33.48 ? 109 LYS C CE  1 
ATOM 2360 N NZ  . LYS C 1 109 ? 156.348 156.688 146.309 1.00 38.08 ? 109 LYS C NZ  1 
ATOM 2361 N N   . THR C 1 110 ? 157.268 165.079 146.085 1.00 29.95 ? 110 THR C N   1 
ATOM 2362 C CA  . THR C 1 110 ? 157.847 166.290 145.526 1.00 29.13 ? 110 THR C CA  1 
ATOM 2363 C C   . THR C 1 110 ? 159.171 166.600 146.203 1.00 28.75 ? 110 THR C C   1 
ATOM 2364 O O   . THR C 1 110 ? 159.309 166.443 147.419 1.00 36.30 ? 110 THR C O   1 
ATOM 2365 C CB  . THR C 1 110 ? 156.894 167.481 145.683 1.00 31.82 ? 110 THR C CB  1 
ATOM 2366 O OG1 . THR C 1 110 ? 155.574 167.096 145.281 1.00 34.95 ? 110 THR C OG1 1 
ATOM 2367 C CG2 . THR C 1 110 ? 157.355 168.646 144.829 1.00 28.18 ? 110 THR C CG2 1 
ATOM 2368 N N   . ASN C 1 111 ? 160.142 167.038 145.406 1.00 32.50 ? 111 ASN C N   1 
ATOM 2369 C CA  . ASN C 1 111 ? 161.425 167.516 145.903 1.00 35.76 ? 111 ASN C CA  1 
ATOM 2370 C C   . ASN C 1 111 ? 161.657 168.917 145.359 1.00 29.82 ? 111 ASN C C   1 
ATOM 2371 O O   . ASN C 1 111 ? 161.647 169.123 144.141 1.00 29.82 ? 111 ASN C O   1 
ATOM 2372 C CB  . ASN C 1 111 ? 162.562 166.577 145.495 1.00 31.62 ? 111 ASN C CB  1 
ATOM 2373 C CG  . ASN C 1 111 ? 162.475 165.228 146.179 1.00 27.28 ? 111 ASN C CG  1 
ATOM 2374 O OD1 . ASN C 1 111 ? 162.874 165.080 147.334 1.00 29.74 ? 111 ASN C OD1 1 
ATOM 2375 N ND2 . ASN C 1 111 ? 161.952 164.237 145.469 1.00 31.69 ? 111 ASN C ND2 1 
ATOM 2376 N N   . MET C 1 112 ? 161.860 169.875 146.260 1.00 28.87 ? 112 MET C N   1 
ATOM 2377 C CA  . MET C 1 112 ? 162.081 171.263 145.883 1.00 20.10 ? 112 MET C CA  1 
ATOM 2378 C C   . MET C 1 112 ? 162.998 171.900 146.917 1.00 25.20 ? 112 MET C C   1 
ATOM 2379 O O   . MET C 1 112 ? 163.433 171.251 147.871 1.00 30.65 ? 112 MET C O   1 
ATOM 2380 C CB  . MET C 1 112 ? 160.755 172.017 145.758 1.00 22.06 ? 112 MET C CB  1 
ATOM 2381 C CG  . MET C 1 112 ? 159.849 171.877 146.964 1.00 25.37 ? 112 MET C CG  1 
ATOM 2382 S SD  . MET C 1 112 ? 158.168 172.417 146.615 1.00 36.99 ? 112 MET C SD  1 
ATOM 2383 C CE  . MET C 1 112 ? 157.318 171.815 148.067 1.00 25.12 ? 112 MET C CE  1 
ATOM 2384 N N   . LYS C 1 113 ? 163.311 173.178 146.711 1.00 26.64 ? 113 LYS C N   1 
ATOM 2385 C CA  . LYS C 1 113 ? 164.168 173.907 147.639 1.00 29.89 ? 113 LYS C CA  1 
ATOM 2386 C C   . LYS C 1 113 ? 163.440 175.061 148.315 1.00 31.54 ? 113 LYS C C   1 
ATOM 2387 O O   . LYS C 1 113 ? 163.384 175.107 149.547 1.00 37.97 ? 113 LYS C O   1 
ATOM 2388 C CB  . LYS C 1 113 ? 165.423 174.409 146.913 1.00 28.96 ? 113 LYS C CB  1 
ATOM 2389 C CG  . LYS C 1 113 ? 166.523 174.893 147.841 1.00 33.46 ? 113 LYS C CG  1 
ATOM 2390 C CD  . LYS C 1 113 ? 167.724 175.400 147.063 1.00 31.25 ? 113 LYS C CD  1 
ATOM 2391 C CE  . LYS C 1 113 ? 168.726 176.077 147.985 1.00 36.76 ? 113 LYS C CE  1 
ATOM 2392 N NZ  . LYS C 1 113 ? 169.853 176.691 147.230 1.00 38.57 ? 113 LYS C NZ  1 
ATOM 2393 N N   . HIS C 1 114 ? 162.865 175.990 147.554 1.00 33.67 ? 114 HIS C N   1 
ATOM 2394 C CA  . HIS C 1 114 ? 162.274 177.196 148.118 1.00 34.05 ? 114 HIS C CA  1 
ATOM 2395 C C   . HIS C 1 114 ? 160.831 177.338 147.662 1.00 31.66 ? 114 HIS C C   1 
ATOM 2396 O O   . HIS C 1 114 ? 160.538 177.225 146.467 1.00 37.45 ? 114 HIS C O   1 
ATOM 2397 C CB  . HIS C 1 114 ? 163.076 178.438 147.718 1.00 32.62 ? 114 HIS C CB  1 
ATOM 2398 C CG  . HIS C 1 114 ? 164.424 178.519 148.364 1.00 30.52 ? 114 HIS C CG  1 
ATOM 2399 N ND1 . HIS C 1 114 ? 164.803 177.693 149.400 1.00 31.54 ? 114 HIS C ND1 1 
ATOM 2400 C CD2 . HIS C 1 114 ? 165.485 179.324 148.118 1.00 37.57 ? 114 HIS C CD2 1 
ATOM 2401 C CE1 . HIS C 1 114 ? 166.037 177.988 149.767 1.00 32.97 ? 114 HIS C CE1 1 
ATOM 2402 N NE2 . HIS C 1 114 ? 166.474 178.974 149.004 1.00 41.34 ? 114 HIS C NE2 1 
ATOM 2403 N N   . VAL C 1 115 ? 159.938 177.582 148.615 1.00 18.65 ? 115 VAL C N   1 
ATOM 2404 C CA  . VAL C 1 115 ? 158.533 177.878 148.342 1.00 20.95 ? 115 VAL C CA  1 
ATOM 2405 C C   . VAL C 1 115 ? 158.252 179.236 148.972 1.00 29.71 ? 115 VAL C C   1 
ATOM 2406 O O   . VAL C 1 115 ? 157.938 179.330 150.163 1.00 24.09 ? 115 VAL C O   1 
ATOM 2407 C CB  . VAL C 1 115 ? 157.590 176.802 148.891 1.00 22.37 ? 115 VAL C CB  1 
ATOM 2408 C CG1 . VAL C 1 115 ? 156.179 177.022 148.370 1.00 20.55 ? 115 VAL C CG1 1 
ATOM 2409 C CG2 . VAL C 1 115 ? 158.092 175.418 148.522 1.00 21.59 ? 115 VAL C CG2 1 
ATOM 2410 N N   . ALA C 1 116 ? 158.365 180.298 148.177 1.00 28.27 ? 116 ALA C N   1 
ATOM 2411 C CA  . ALA C 1 116 ? 158.183 181.662 148.655 1.00 19.56 ? 116 ALA C CA  1 
ATOM 2412 C C   . ALA C 1 116 ? 156.959 182.267 147.986 1.00 22.30 ? 116 ALA C C   1 
ATOM 2413 O O   . ALA C 1 116 ? 156.914 182.383 146.757 1.00 21.11 ? 116 ALA C O   1 
ATOM 2414 C CB  . ALA C 1 116 ? 159.423 182.512 148.372 1.00 24.56 ? 116 ALA C CB  1 
ATOM 2415 N N   . GLY C 1 117 ? 155.973 182.647 148.794 1.00 23.46 ? 117 GLY C N   1 
ATOM 2416 C CA  . GLY C 1 117 ? 154.784 183.307 148.275 1.00 22.14 ? 117 GLY C CA  1 
ATOM 2417 C C   . GLY C 1 117 ? 154.024 182.493 147.252 1.00 15.74 ? 117 GLY C C   1 
ATOM 2418 O O   . GLY C 1 117 ? 153.464 183.059 146.306 1.00 20.89 ? 117 GLY C O   1 
ATOM 2419 N N   . ALA C 1 118 ? 153.970 181.176 147.433 1.00 16.73 ? 118 ALA C N   1 
ATOM 2420 C CA  . ALA C 1 118 ? 153.435 180.283 146.417 1.00 17.08 ? 118 ALA C CA  1 
ATOM 2421 C C   . ALA C 1 118 ? 152.660 179.164 147.103 1.00 12.57 ? 118 ALA C C   1 
ATOM 2422 O O   . ALA C 1 118 ? 152.368 179.221 148.301 1.00 17.19 ? 118 ALA C O   1 
ATOM 2423 C CB  . ALA C 1 118 ? 154.565 179.745 145.531 1.00 19.48 ? 118 ALA C CB  1 
ATOM 2424 N N   . ALA C 1 119 ? 152.310 178.144 146.324 1.00 15.85 ? 119 ALA C N   1 
ATOM 2425 C CA  . ALA C 1 119 ? 151.660 176.948 146.833 1.00 21.52 ? 119 ALA C CA  1 
ATOM 2426 C C   . ALA C 1 119 ? 152.321 175.732 146.205 1.00 22.91 ? 119 ALA C C   1 
ATOM 2427 O O   . ALA C 1 119 ? 152.628 175.735 145.010 1.00 25.54 ? 119 ALA C O   1 
ATOM 2428 C CB  . ALA C 1 119 ? 150.158 176.948 146.532 1.00 26.27 ? 119 ALA C CB  1 
ATOM 2429 N N   . ALA C 1 120 ? 152.536 174.697 147.011 1.00 24.69 ? 120 ALA C N   1 
ATOM 2430 C CA  . ALA C 1 120 ? 153.218 173.507 146.527 1.00 22.52 ? 120 ALA C CA  1 
ATOM 2431 C C   . ALA C 1 120 ? 152.842 172.321 147.402 1.00 20.24 ? 120 ALA C C   1 
ATOM 2432 O O   . ALA C 1 120 ? 152.302 172.481 148.500 1.00 15.88 ? 120 ALA C O   1 
ATOM 2433 C CB  . ALA C 1 120 ? 154.736 173.705 146.502 1.00 22.31 ? 120 ALA C CB  1 
ATOM 2434 N N   . ALA C 1 121 ? 153.136 171.125 146.889 1.00 26.64 ? 121 ALA C N   1 
ATOM 2435 C CA  . ALA C 1 121 ? 152.882 169.868 147.593 1.00 20.64 ? 121 ALA C CA  1 
ATOM 2436 C C   . ALA C 1 121 ? 151.419 169.743 148.014 1.00 14.52 ? 121 ALA C C   1 
ATOM 2437 O O   . ALA C 1 121 ? 151.108 169.322 149.129 1.00 24.01 ? 121 ALA C O   1 
ATOM 2438 C CB  . ALA C 1 121 ? 153.812 169.711 148.798 1.00 21.13 ? 121 ALA C CB  1 
ATOM 2439 N N   . GLY C 1 122 ? 150.514 170.110 147.111 1.00 16.58 ? 122 GLY C N   1 
ATOM 2440 C CA  . GLY C 1 122 ? 149.092 169.974 147.356 1.00 17.78 ? 122 GLY C CA  1 
ATOM 2441 C C   . GLY C 1 122 ? 148.559 170.830 148.485 1.00 27.05 ? 122 GLY C C   1 
ATOM 2442 O O   . GLY C 1 122 ? 147.796 170.350 149.329 1.00 25.18 ? 122 GLY C O   1 
ATOM 2443 N N   . ALA C 1 123 ? 148.946 172.103 148.507 1.00 29.98 ? 123 ALA C N   1 
ATOM 2444 C CA  . ALA C 1 123 ? 148.546 173.034 149.551 1.00 17.91 ? 123 ALA C CA  1 
ATOM 2445 C C   . ALA C 1 123 ? 147.715 174.160 148.952 1.00 23.11 ? 123 ALA C C   1 
ATOM 2446 O O   . ALA C 1 123 ? 147.981 174.614 147.835 1.00 27.15 ? 123 ALA C O   1 
ATOM 2447 C CB  . ALA C 1 123 ? 149.769 173.605 150.267 1.00 14.96 ? 123 ALA C CB  1 
ATOM 2448 N N   . VAL C 1 124 ? 146.709 174.611 149.698 1.00 22.29 ? 124 VAL C N   1 
ATOM 2449 C CA  . VAL C 1 124 ? 145.798 175.660 149.253 1.00 22.66 ? 124 VAL C CA  1 
ATOM 2450 C C   . VAL C 1 124 ? 146.098 176.931 150.034 1.00 21.01 ? 124 VAL C C   1 
ATOM 2451 O O   . VAL C 1 124 ? 146.105 176.919 151.269 1.00 29.05 ? 124 VAL C O   1 
ATOM 2452 C CB  . VAL C 1 124 ? 144.328 175.245 149.429 1.00 12.52 ? 124 VAL C CB  1 
ATOM 2453 C CG1 . VAL C 1 124 ? 143.429 176.124 148.579 1.00 22.96 ? 124 VAL C CG1 1 
ATOM 2454 C CG2 . VAL C 1 124 ? 144.146 173.784 149.066 1.00 21.31 ? 124 VAL C CG2 1 
ATOM 2455 N N   . VAL C 1 125 ? 146.349 178.023 149.317 1.00 23.70 ? 125 VAL C N   1 
ATOM 2456 C CA  . VAL C 1 125 ? 146.629 179.317 149.966 1.00 23.30 ? 125 VAL C CA  1 
ATOM 2457 C C   . VAL C 1 125 ? 145.289 180.028 150.107 1.00 25.73 ? 125 VAL C C   1 
ATOM 2458 O O   . VAL C 1 125 ? 144.900 180.878 149.303 1.00 20.16 ? 125 VAL C O   1 
ATOM 2459 C CB  . VAL C 1 125 ? 147.659 180.144 149.192 1.00 15.60 ? 125 VAL C CB  1 
ATOM 2460 C CG1 . VAL C 1 125 ? 148.039 181.383 149.984 1.00 18.99 ? 125 VAL C CG1 1 
ATOM 2461 C CG2 . VAL C 1 125 ? 148.886 179.310 148.890 1.00 19.98 ? 125 VAL C CG2 1 
ATOM 2462 N N   . GLY C 1 126 ? 144.571 179.687 151.171 1.00 32.52 ? 126 GLY C N   1 
ATOM 2463 C CA  . GLY C 1 126 ? 143.411 180.460 151.567 1.00 31.95 ? 126 GLY C CA  1 
ATOM 2464 C C   . GLY C 1 126 ? 142.097 180.143 150.885 1.00 27.90 ? 126 GLY C C   1 
ATOM 2465 O O   . GLY C 1 126 ? 142.000 180.153 149.655 1.00 20.23 ? 126 GLY C O   1 
ATOM 2466 N N   . GLY C 1 127 ? 141.074 179.864 151.689 1.00 34.95 ? 127 GLY C N   1 
ATOM 2467 C CA  . GLY C 1 127 ? 139.705 179.837 151.215 1.00 24.24 ? 127 GLY C CA  1 
ATOM 2468 C C   . GLY C 1 127 ? 138.966 181.048 151.745 1.00 23.88 ? 127 GLY C C   1 
ATOM 2469 O O   . GLY C 1 127 ? 138.678 181.122 152.943 1.00 26.23 ? 127 GLY C O   1 
ATOM 2470 N N   . LEU C 1 128 ? 138.660 182.002 150.863 1.00 28.08 ? 128 LEU C N   1 
ATOM 2471 C CA  . LEU C 1 128 ? 138.215 183.337 151.269 1.00 27.75 ? 128 LEU C CA  1 
ATOM 2472 C C   . LEU C 1 128 ? 139.225 183.983 152.212 1.00 20.50 ? 128 LEU C C   1 
ATOM 2473 O O   . LEU C 1 128 ? 138.863 184.669 153.170 1.00 30.31 ? 128 LEU C O   1 
ATOM 2474 C CB  . LEU C 1 128 ? 136.823 183.307 151.902 1.00 24.56 ? 128 LEU C CB  1 
ATOM 2475 C CG  . LEU C 1 128 ? 135.639 183.155 150.952 1.00 31.30 ? 128 LEU C CG  1 
ATOM 2476 C CD1 . LEU C 1 128 ? 134.366 182.859 151.717 1.00 26.36 ? 128 LEU C CD1 1 
ATOM 2477 C CD2 . LEU C 1 128 ? 135.486 184.423 150.143 1.00 31.54 ? 128 LEU C CD2 1 
ATOM 2478 N N   . GLY C 1 129 ? 140.506 183.766 151.931 1.00 18.68 ? 129 GLY C N   1 
ATOM 2479 C CA  . GLY C 1 129 ? 141.569 184.283 152.767 1.00 20.43 ? 129 GLY C CA  1 
ATOM 2480 C C   . GLY C 1 129 ? 142.939 184.052 152.168 1.00 18.98 ? 129 GLY C C   1 
ATOM 2481 O O   . GLY C 1 129 ? 143.085 183.983 150.944 1.00 27.51 ? 129 GLY C O   1 
ATOM 2482 N N   . GLY C 1 130 ? 143.950 183.928 153.020 1.00 18.01 ? 130 GLY C N   1 
ATOM 2483 C CA  . GLY C 1 130 ? 145.308 183.741 152.556 1.00 18.72 ? 130 GLY C CA  1 
ATOM 2484 C C   . GLY C 1 130 ? 146.224 184.849 153.024 1.00 22.00 ? 130 GLY C C   1 
ATOM 2485 O O   . GLY C 1 130 ? 146.471 184.994 154.225 1.00 23.80 ? 130 GLY C O   1 
ATOM 2486 N N   . TYR C 1 131 ? 146.732 185.641 152.086 1.00 36.73 ? 131 TYR C N   1 
ATOM 2487 C CA  . TYR C 1 131 ? 147.574 186.794 152.392 1.00 37.70 ? 131 TYR C CA  1 
ATOM 2488 C C   . TYR C 1 131 ? 146.826 188.025 151.896 1.00 35.99 ? 131 TYR C C   1 
ATOM 2489 O O   . TYR C 1 131 ? 147.035 188.489 150.772 1.00 30.29 ? 131 TYR C O   1 
ATOM 2490 C CB  . TYR C 1 131 ? 148.956 186.652 151.758 1.00 31.46 ? 131 TYR C CB  1 
ATOM 2491 C CG  . TYR C 1 131 ? 149.796 185.589 152.428 1.00 33.10 ? 131 TYR C CG  1 
ATOM 2492 C CD1 . TYR C 1 131 ? 149.570 184.243 152.178 1.00 33.66 ? 131 TYR C CD1 1 
ATOM 2493 C CD2 . TYR C 1 131 ? 150.797 185.930 153.329 1.00 34.31 ? 131 TYR C CD2 1 
ATOM 2494 C CE1 . TYR C 1 131 ? 150.324 183.266 152.792 1.00 29.12 ? 131 TYR C CE1 1 
ATOM 2495 C CE2 . TYR C 1 131 ? 151.557 184.957 153.951 1.00 35.75 ? 131 TYR C CE2 1 
ATOM 2496 C CZ  . TYR C 1 131 ? 151.315 183.627 153.678 1.00 36.00 ? 131 TYR C CZ  1 
ATOM 2497 O OH  . TYR C 1 131 ? 152.063 182.650 154.292 1.00 36.25 ? 131 TYR C OH  1 
ATOM 2498 N N   . MET C 1 132 ? 145.949 188.550 152.747 1.00 41.84 ? 132 MET C N   1 
ATOM 2499 C CA  . MET C 1 132 ? 145.057 189.655 152.408 1.00 40.74 ? 132 MET C CA  1 
ATOM 2500 C C   . MET C 1 132 ? 145.279 190.757 153.439 1.00 36.12 ? 132 MET C C   1 
ATOM 2501 O O   . MET C 1 132 ? 144.550 190.851 154.428 1.00 39.09 ? 132 MET C O   1 
ATOM 2502 C CB  . MET C 1 132 ? 143.605 189.180 152.382 1.00 38.98 ? 132 MET C CB  1 
ATOM 2503 C CG  . MET C 1 132 ? 143.298 188.210 151.251 1.00 34.61 ? 132 MET C CG  1 
ATOM 2504 S SD  . MET C 1 132 ? 141.611 187.579 151.284 1.00 52.81 ? 132 MET C SD  1 
ATOM 2505 C CE  . MET C 1 132 ? 140.694 189.028 150.779 1.00 46.16 ? 132 MET C CE  1 
ATOM 2506 N N   . LEU C 1 133 ? 146.279 191.606 153.185 1.00 34.63 ? 133 LEU C N   1 
ATOM 2507 C CA  . LEU C 1 133 ? 146.685 192.604 154.170 1.00 32.27 ? 133 LEU C CA  1 
ATOM 2508 C C   . LEU C 1 133 ? 145.544 193.560 154.496 1.00 37.58 ? 133 LEU C C   1 
ATOM 2509 O O   . LEU C 1 133 ? 145.203 193.759 155.667 1.00 43.85 ? 133 LEU C O   1 
ATOM 2510 C CB  . LEU C 1 133 ? 147.909 193.365 153.655 1.00 37.63 ? 133 LEU C CB  1 
ATOM 2511 C CG  . LEU C 1 133 ? 148.626 194.327 154.600 1.00 38.15 ? 133 LEU C CG  1 
ATOM 2512 C CD1 . LEU C 1 133 ? 150.111 194.355 154.292 1.00 40.68 ? 133 LEU C CD1 1 
ATOM 2513 C CD2 . LEU C 1 133 ? 148.042 195.720 154.467 1.00 41.94 ? 133 LEU C CD2 1 
ATOM 2514 N N   . GLY C 1 134 ? 144.945 194.161 153.474 1.00 45.07 ? 134 GLY C N   1 
ATOM 2515 C CA  . GLY C 1 134 ? 143.818 195.047 153.686 1.00 39.06 ? 134 GLY C CA  1 
ATOM 2516 C C   . GLY C 1 134 ? 142.552 194.517 153.047 1.00 43.64 ? 134 GLY C C   1 
ATOM 2517 O O   . GLY C 1 134 ? 142.435 194.496 151.819 1.00 54.53 ? 134 GLY C O   1 
ATOM 2518 N N   . SER C 1 135 ? 141.596 194.087 153.866 1.00 27.65 ? 135 SER C N   1 
ATOM 2519 C CA  . SER C 1 135 ? 140.377 193.482 153.355 1.00 34.47 ? 135 SER C CA  1 
ATOM 2520 C C   . SER C 1 135 ? 139.182 193.971 154.158 1.00 36.67 ? 135 SER C C   1 
ATOM 2521 O O   . SER C 1 135 ? 139.303 194.381 155.314 1.00 42.71 ? 135 SER C O   1 
ATOM 2522 C CB  . SER C 1 135 ? 140.448 191.951 153.395 1.00 36.98 ? 135 SER C CB  1 
ATOM 2523 O OG  . SER C 1 135 ? 139.417 191.374 152.614 1.00 39.23 ? 135 SER C OG  1 
ATOM 2524 N N   . ALA C 1 136 ? 138.017 193.923 153.516 1.00 30.93 ? 136 ALA C N   1 
ATOM 2525 C CA  . ALA C 1 136 ? 136.757 194.278 154.163 1.00 36.52 ? 136 ALA C CA  1 
ATOM 2526 C C   . ALA C 1 136 ? 135.659 193.479 153.480 1.00 37.11 ? 136 ALA C C   1 
ATOM 2527 O O   . ALA C 1 136 ? 135.298 193.775 152.337 1.00 46.08 ? 136 ALA C O   1 
ATOM 2528 C CB  . ALA C 1 136 ? 136.490 195.777 154.075 1.00 35.70 ? 136 ALA C CB  1 
ATOM 2529 N N   . MET C 1 137 ? 135.138 192.466 154.167 1.00 21.54 ? 137 MET C N   1 
ATOM 2530 C CA  . MET C 1 137 ? 134.135 191.573 153.605 1.00 27.00 ? 137 MET C CA  1 
ATOM 2531 C C   . MET C 1 137 ? 132.876 191.614 154.458 1.00 28.23 ? 137 MET C C   1 
ATOM 2532 O O   . MET C 1 137 ? 132.935 191.381 155.668 1.00 31.94 ? 137 MET C O   1 
ATOM 2533 C CB  . MET C 1 137 ? 134.671 190.143 153.511 1.00 34.69 ? 137 MET C CB  1 
ATOM 2534 C CG  . MET C 1 137 ? 135.969 190.026 152.729 1.00 36.57 ? 137 MET C CG  1 
ATOM 2535 S SD  . MET C 1 137 ? 136.947 188.586 153.197 1.00 51.85 ? 137 MET C SD  1 
ATOM 2536 C CE  . MET C 1 137 ? 135.925 187.265 152.557 1.00 38.49 ? 137 MET C CE  1 
ATOM 2537 N N   . SER C 1 138 ? 131.744 191.900 153.825 1.00 30.76 ? 138 SER C N   1 
ATOM 2538 C CA  . SER C 1 138 ? 130.460 191.963 154.510 1.00 23.74 ? 138 SER C CA  1 
ATOM 2539 C C   . SER C 1 138 ? 129.729 190.637 154.341 1.00 26.88 ? 138 SER C C   1 
ATOM 2540 O O   . SER C 1 138 ? 129.585 190.142 153.219 1.00 34.27 ? 138 SER C O   1 
ATOM 2541 C CB  . SER C 1 138 ? 129.606 193.111 153.970 1.00 21.06 ? 138 SER C CB  1 
ATOM 2542 O OG  . SER C 1 138 ? 129.263 192.898 152.613 1.00 34.67 ? 138 SER C OG  1 
ATOM 2543 N N   . ARG C 1 139 ? 129.268 190.079 155.456 1.00 23.95 ? 139 ARG C N   1 
ATOM 2544 C CA  . ARG C 1 139 ? 128.591 188.788 155.488 1.00 24.93 ? 139 ARG C CA  1 
ATOM 2545 C C   . ARG C 1 139 ? 129.369 187.689 154.756 1.00 25.46 ? 139 ARG C C   1 
ATOM 2546 O O   . ARG C 1 139 ? 128.867 187.101 153.793 1.00 24.13 ? 139 ARG C O   1 
ATOM 2547 C CB  . ARG C 1 139 ? 127.181 188.910 154.926 1.00 27.75 ? 139 ARG C CB  1 
ATOM 2548 C CG  . ARG C 1 139 ? 126.235 187.810 155.381 1.00 23.96 ? 139 ARG C CG  1 
ATOM 2549 C CD  . ARG C 1 139 ? 124.911 188.379 155.854 1.00 27.63 ? 139 ARG C CD  1 
ATOM 2550 N NE  . ARG C 1 139 ? 124.010 188.670 154.746 1.00 38.05 ? 139 ARG C NE  1 
ATOM 2551 C CZ  . ARG C 1 139 ? 123.115 187.818 154.264 1.00 36.72 ? 139 ARG C CZ  1 
ATOM 2552 N NH1 . ARG C 1 139 ? 122.982 186.601 154.765 1.00 34.68 ? 139 ARG C NH1 1 
ATOM 2553 N NH2 . ARG C 1 139 ? 122.334 188.196 153.257 1.00 24.54 ? 139 ARG C NH2 1 
ATOM 2554 N N   . PRO C 1 140 ? 130.604 187.389 155.186 1.00 30.70 ? 140 PRO C N   1 
ATOM 2555 C CA  . PRO C 1 140 ? 131.330 186.266 154.580 1.00 18.23 ? 140 PRO C CA  1 
ATOM 2556 C C   . PRO C 1 140 ? 130.959 184.948 155.237 1.00 16.25 ? 140 PRO C C   1 
ATOM 2557 O O   . PRO C 1 140 ? 131.158 184.772 156.442 1.00 19.67 ? 140 PRO C O   1 
ATOM 2558 C CB  . PRO C 1 140 ? 132.804 186.627 154.816 1.00 16.75 ? 140 PRO C CB  1 
ATOM 2559 C CG  . PRO C 1 140 ? 132.803 187.868 155.702 1.00 23.33 ? 140 PRO C CG  1 
ATOM 2560 C CD  . PRO C 1 140 ? 131.415 188.050 156.218 1.00 25.51 ? 140 PRO C CD  1 
ATOM 2561 N N   . LEU C 1 141 ? 130.422 184.012 154.456 1.00 17.64 ? 141 LEU C N   1 
ATOM 2562 C CA  . LEU C 1 141 ? 129.858 182.783 154.994 1.00 12.64 ? 141 LEU C CA  1 
ATOM 2563 C C   . LEU C 1 141 ? 130.497 181.573 154.328 1.00 15.71 ? 141 LEU C C   1 
ATOM 2564 O O   . LEU C 1 141 ? 130.585 181.509 153.099 1.00 15.27 ? 141 LEU C O   1 
ATOM 2565 C CB  . LEU C 1 141 ? 128.337 182.757 154.800 1.00 21.43 ? 141 LEU C CB  1 
ATOM 2566 C CG  . LEU C 1 141 ? 127.610 181.420 154.940 1.00 18.81 ? 141 LEU C CG  1 
ATOM 2567 C CD1 . LEU C 1 141 ? 127.856 180.799 156.299 1.00 16.87 ? 141 LEU C CD1 1 
ATOM 2568 C CD2 . LEU C 1 141 ? 126.120 181.596 154.692 1.00 22.15 ? 141 LEU C CD2 1 
ATOM 2569 N N   . ILE C 1 142 ? 130.942 180.623 155.148 1.00 21.87 ? 142 ILE C N   1 
ATOM 2570 C CA  . ILE C 1 142 ? 131.437 179.330 154.689 1.00 10.68 ? 142 ILE C CA  1 
ATOM 2571 C C   . ILE C 1 142 ? 130.720 178.250 155.486 1.00 15.07 ? 142 ILE C C   1 
ATOM 2572 O O   . ILE C 1 142 ? 130.858 178.192 156.713 1.00 28.23 ? 142 ILE C O   1 
ATOM 2573 C CB  . ILE C 1 142 ? 132.959 179.191 154.864 1.00 19.51 ? 142 ILE C CB  1 
ATOM 2574 C CG1 . ILE C 1 142 ? 133.698 180.235 154.029 1.00 30.02 ? 142 ILE C CG1 1 
ATOM 2575 C CG2 . ILE C 1 142 ? 133.413 177.787 154.493 1.00 16.66 ? 142 ILE C CG2 1 
ATOM 2576 C CD1 . ILE C 1 142 ? 135.202 180.061 154.030 1.00 17.00 ? 142 ILE C CD1 1 
ATOM 2577 N N   . HIS C 1 143 ? 129.963 177.395 154.802 1.00 11.23 ? 143 HIS C N   1 
ATOM 2578 C CA  . HIS C 1 143 ? 129.292 176.285 155.475 1.00 19.18 ? 143 HIS C CA  1 
ATOM 2579 C C   . HIS C 1 143 ? 129.308 175.055 154.580 1.00 17.52 ? 143 HIS C C   1 
ATOM 2580 O O   . HIS C 1 143 ? 128.654 175.031 153.535 1.00 24.83 ? 143 HIS C O   1 
ATOM 2581 C CB  . HIS C 1 143 ? 127.864 176.659 155.889 1.00 14.31 ? 143 HIS C CB  1 
ATOM 2582 C CG  . HIS C 1 143 ? 126.955 177.026 154.757 1.00 11.13 ? 143 HIS C CG  1 
ATOM 2583 N ND1 . HIS C 1 143 ? 126.951 178.277 154.179 1.00 28.99 ? 143 HIS C ND1 1 
ATOM 2584 C CD2 . HIS C 1 143 ? 125.986 176.319 154.129 1.00 18.83 ? 143 HIS C CD2 1 
ATOM 2585 C CE1 . HIS C 1 143 ? 126.033 178.318 153.231 1.00 19.62 ? 143 HIS C CE1 1 
ATOM 2586 N NE2 . HIS C 1 143 ? 125.435 177.143 153.178 1.00 29.50 ? 143 HIS C NE2 1 
ATOM 2587 N N   . PHE C 1 144 ? 130.047 174.029 154.997 1.00 14.58 ? 144 PHE C N   1 
ATOM 2588 C CA  . PHE C 1 144 ? 130.108 172.798 154.221 1.00 14.97 ? 144 PHE C CA  1 
ATOM 2589 C C   . PHE C 1 144 ? 128.792 172.033 154.245 1.00 7.79  ? 144 PHE C C   1 
ATOM 2590 O O   . PHE C 1 144 ? 128.529 171.250 153.328 1.00 34.64 ? 144 PHE C O   1 
ATOM 2591 C CB  . PHE C 1 144 ? 131.242 171.912 154.733 1.00 18.95 ? 144 PHE C CB  1 
ATOM 2592 C CG  . PHE C 1 144 ? 132.599 172.321 154.238 1.00 14.78 ? 144 PHE C CG  1 
ATOM 2593 C CD1 . PHE C 1 144 ? 133.212 173.463 154.726 1.00 13.58 ? 144 PHE C CD1 1 
ATOM 2594 C CD2 . PHE C 1 144 ? 133.259 171.568 153.283 1.00 15.27 ? 144 PHE C CD2 1 
ATOM 2595 C CE1 . PHE C 1 144 ? 134.459 173.843 154.272 1.00 17.23 ? 144 PHE C CE1 1 
ATOM 2596 C CE2 . PHE C 1 144 ? 134.508 171.944 152.825 1.00 15.09 ? 144 PHE C CE2 1 
ATOM 2597 C CZ  . PHE C 1 144 ? 135.108 173.084 153.319 1.00 15.67 ? 144 PHE C CZ  1 
ATOM 2598 N N   . GLY C 1 145 ? 127.958 172.249 155.256 1.00 0.00  ? 145 GLY C N   1 
ATOM 2599 C CA  . GLY C 1 145 ? 126.704 171.534 155.353 1.00 9.34  ? 145 GLY C CA  1 
ATOM 2600 C C   . GLY C 1 145 ? 125.678 172.013 154.342 1.00 16.15 ? 145 GLY C C   1 
ATOM 2601 O O   . GLY C 1 145 ? 125.842 173.022 153.656 1.00 9.66  ? 145 GLY C O   1 
ATOM 2602 N N   . ASN C 1 146 ? 124.591 171.251 154.252 1.00 20.42 ? 146 ASN C N   1 
ATOM 2603 C CA  . ASN C 1 146 ? 123.505 171.590 153.346 1.00 21.22 ? 146 ASN C CA  1 
ATOM 2604 C C   . ASN C 1 146 ? 122.811 172.872 153.793 1.00 19.80 ? 146 ASN C C   1 
ATOM 2605 O O   . ASN C 1 146 ? 122.702 173.164 154.986 1.00 22.01 ? 146 ASN C O   1 
ATOM 2606 C CB  . ASN C 1 146 ? 122.494 170.446 153.270 1.00 20.35 ? 146 ASN C CB  1 
ATOM 2607 C CG  . ASN C 1 146 ? 123.102 169.163 152.746 1.00 25.80 ? 146 ASN C CG  1 
ATOM 2608 O OD1 . ASN C 1 146 ? 123.108 168.912 151.542 1.00 25.52 ? 146 ASN C OD1 1 
ATOM 2609 N ND2 . ASN C 1 146 ? 123.620 168.341 153.652 1.00 23.77 ? 146 ASN C ND2 1 
ATOM 2610 N N   . ASP C 1 147 ? 122.336 173.639 152.815 1.00 24.50 ? 147 ASP C N   1 
ATOM 2611 C CA  . ASP C 1 147 ? 121.683 174.917 153.060 1.00 22.90 ? 147 ASP C CA  1 
ATOM 2612 C C   . ASP C 1 147 ? 120.238 174.851 152.589 1.00 18.37 ? 147 ASP C C   1 
ATOM 2613 O O   . ASP C 1 147 ? 119.966 174.418 151.464 1.00 31.21 ? 147 ASP C O   1 
ATOM 2614 C CB  . ASP C 1 147 ? 122.417 176.055 152.349 1.00 21.68 ? 147 ASP C CB  1 
ATOM 2615 C CG  . ASP C 1 147 ? 122.063 177.417 152.910 1.00 30.17 ? 147 ASP C CG  1 
ATOM 2616 O OD1 . ASP C 1 147 ? 121.423 177.472 153.980 1.00 29.97 ? 147 ASP C OD1 1 
ATOM 2617 O OD2 . ASP C 1 147 ? 122.425 178.433 152.281 1.00 38.96 ? 147 ASP C OD2 1 
ATOM 2618 N N   . TYR C 1 148 ? 119.319 175.278 153.452 1.00 19.69 ? 148 TYR C N   1 
ATOM 2619 C CA  . TYR C 1 148 ? 117.905 175.379 153.118 1.00 22.88 ? 148 TYR C CA  1 
ATOM 2620 C C   . TYR C 1 148 ? 117.417 176.769 153.491 1.00 26.71 ? 148 TYR C C   1 
ATOM 2621 O O   . TYR C 1 148 ? 117.664 177.237 154.606 1.00 23.19 ? 148 TYR C O   1 
ATOM 2622 C CB  . TYR C 1 148 ? 117.082 174.310 153.846 1.00 16.87 ? 148 TYR C CB  1 
ATOM 2623 C CG  . TYR C 1 148 ? 115.628 174.254 153.429 1.00 15.05 ? 148 TYR C CG  1 
ATOM 2624 C CD1 . TYR C 1 148 ? 114.684 175.091 154.012 1.00 19.73 ? 148 TYR C CD1 1 
ATOM 2625 C CD2 . TYR C 1 148 ? 115.199 173.364 152.455 1.00 19.74 ? 148 TYR C CD2 1 
ATOM 2626 C CE1 . TYR C 1 148 ? 113.356 175.040 153.637 1.00 22.95 ? 148 TYR C CE1 1 
ATOM 2627 C CE2 . TYR C 1 148 ? 113.872 173.303 152.076 1.00 17.95 ? 148 TYR C CE2 1 
ATOM 2628 C CZ  . TYR C 1 148 ? 112.956 174.146 152.669 1.00 19.49 ? 148 TYR C CZ  1 
ATOM 2629 O OH  . TYR C 1 148 ? 111.634 174.093 152.292 1.00 24.05 ? 148 TYR C OH  1 
ATOM 2630 N N   . GLU C 1 149 ? 116.728 177.424 152.559 1.00 31.72 ? 149 GLU C N   1 
ATOM 2631 C CA  . GLU C 1 149 ? 116.203 178.766 152.774 1.00 26.09 ? 149 GLU C CA  1 
ATOM 2632 C C   . GLU C 1 149 ? 114.765 178.830 152.285 1.00 25.67 ? 149 GLU C C   1 
ATOM 2633 O O   . GLU C 1 149 ? 114.484 178.497 151.129 1.00 34.57 ? 149 GLU C O   1 
ATOM 2634 C CB  . GLU C 1 149 ? 117.055 179.817 152.056 1.00 31.89 ? 149 GLU C CB  1 
ATOM 2635 C CG  . GLU C 1 149 ? 118.420 180.044 152.682 1.00 36.78 ? 149 GLU C CG  1 
ATOM 2636 C CD  . GLU C 1 149 ? 119.184 181.176 152.023 1.00 43.02 ? 149 GLU C CD  1 
ATOM 2637 O OE1 . GLU C 1 149 ? 118.583 181.904 151.205 1.00 35.95 ? 149 GLU C OE1 1 
ATOM 2638 O OE2 . GLU C 1 149 ? 120.385 181.337 152.322 1.00 47.50 ? 149 GLU C OE2 1 
ATOM 2639 N N   . ASP C 1 150 ? 113.862 179.259 153.166 1.00 33.18 ? 150 ASP C N   1 
ATOM 2640 C CA  . ASP C 1 150 ? 112.452 179.473 152.837 1.00 28.31 ? 150 ASP C CA  1 
ATOM 2641 C C   . ASP C 1 150 ? 112.127 180.908 153.240 1.00 30.42 ? 150 ASP C C   1 
ATOM 2642 O O   . ASP C 1 150 ? 111.680 181.163 154.361 1.00 32.11 ? 150 ASP C O   1 
ATOM 2643 C CB  . ASP C 1 150 ? 111.557 178.461 153.545 1.00 29.78 ? 150 ASP C CB  1 
ATOM 2644 C CG  . ASP C 1 150 ? 110.139 178.466 153.012 1.00 33.97 ? 150 ASP C CG  1 
ATOM 2645 O OD1 . ASP C 1 150 ? 109.896 179.106 151.968 1.00 38.41 ? 150 ASP C OD1 1 
ATOM 2646 O OD2 . ASP C 1 150 ? 109.265 177.829 153.638 1.00 38.20 ? 150 ASP C OD2 1 
ATOM 2647 N N   . ARG C 1 151 ? 112.351 181.842 152.320 1.00 35.19 ? 151 ARG C N   1 
ATOM 2648 C CA  . ARG C 1 151 ? 112.238 183.266 152.600 1.00 27.97 ? 151 ARG C CA  1 
ATOM 2649 C C   . ARG C 1 151 ? 110.919 183.808 152.065 1.00 21.74 ? 151 ARG C C   1 
ATOM 2650 O O   . ARG C 1 151 ? 110.540 183.523 150.925 1.00 20.50 ? 151 ARG C O   1 
ATOM 2651 C CB  . ARG C 1 151 ? 113.408 184.034 151.982 1.00 22.91 ? 151 ARG C CB  1 
ATOM 2652 C CG  . ARG C 1 151 ? 114.727 183.848 152.709 1.00 23.72 ? 151 ARG C CG  1 
ATOM 2653 C CD  . ARG C 1 151 ? 115.792 184.780 152.158 1.00 24.37 ? 151 ARG C CD  1 
ATOM 2654 N NE  . ARG C 1 151 ? 116.982 184.808 152.999 1.00 26.76 ? 151 ARG C NE  1 
ATOM 2655 C CZ  . ARG C 1 151 ? 118.030 185.591 152.785 1.00 28.52 ? 151 ARG C CZ  1 
ATOM 2656 N NH1 . ARG C 1 151 ? 118.071 186.429 151.762 1.00 25.66 ? 151 ARG C NH1 1 
ATOM 2657 N NH2 . ARG C 1 151 ? 119.063 185.535 153.621 1.00 30.43 ? 151 ARG C NH2 1 
ATOM 2658 N N   . TYR C 1 152 ? 110.225 184.585 152.897 1.00 25.76 ? 152 TYR C N   1 
ATOM 2659 C CA  . TYR C 1 152 ? 108.999 185.287 152.518 1.00 21.78 ? 152 TYR C CA  1 
ATOM 2660 C C   . TYR C 1 152 ? 109.175 186.733 152.974 1.00 23.68 ? 152 TYR C C   1 
ATOM 2661 O O   . TYR C 1 152 ? 108.845 187.083 154.110 1.00 26.45 ? 152 TYR C O   1 
ATOM 2662 C CB  . TYR C 1 152 ? 107.765 184.628 153.136 1.00 17.43 ? 152 TYR C CB  1 
ATOM 2663 C CG  . TYR C 1 152 ? 106.446 185.309 152.819 1.00 23.10 ? 152 TYR C CG  1 
ATOM 2664 C CD1 . TYR C 1 152 ? 106.329 186.199 151.758 1.00 24.33 ? 152 TYR C CD1 1 
ATOM 2665 C CD2 . TYR C 1 152 ? 105.314 185.050 153.579 1.00 27.63 ? 152 TYR C CD2 1 
ATOM 2666 C CE1 . TYR C 1 152 ? 105.127 186.819 151.474 1.00 25.11 ? 152 TYR C CE1 1 
ATOM 2667 C CE2 . TYR C 1 152 ? 104.107 185.664 153.300 1.00 23.82 ? 152 TYR C CE2 1 
ATOM 2668 C CZ  . TYR C 1 152 ? 104.019 186.546 152.246 1.00 24.64 ? 152 TYR C CZ  1 
ATOM 2669 O OH  . TYR C 1 152 ? 102.820 187.158 151.964 1.00 29.62 ? 152 TYR C OH  1 
ATOM 2670 N N   . TYR C 1 153 ? 109.698 187.569 152.081 1.00 30.47 ? 153 TYR C N   1 
ATOM 2671 C CA  . TYR C 1 153 ? 109.953 188.974 152.367 1.00 26.34 ? 153 TYR C CA  1 
ATOM 2672 C C   . TYR C 1 153 ? 108.837 189.809 151.754 1.00 24.83 ? 153 TYR C C   1 
ATOM 2673 O O   . TYR C 1 153 ? 108.573 189.710 150.551 1.00 30.00 ? 153 TYR C O   1 
ATOM 2674 C CB  . TYR C 1 153 ? 111.312 189.408 151.814 1.00 22.54 ? 153 TYR C CB  1 
ATOM 2675 C CG  . TYR C 1 153 ? 112.508 188.921 152.607 1.00 22.15 ? 153 TYR C CG  1 
ATOM 2676 C CD1 . TYR C 1 153 ? 112.385 187.905 153.546 1.00 25.79 ? 153 TYR C CD1 1 
ATOM 2677 C CD2 . TYR C 1 153 ? 113.763 189.478 152.410 1.00 21.51 ? 153 TYR C CD2 1 
ATOM 2678 C CE1 . TYR C 1 153 ? 113.476 187.461 154.266 1.00 26.52 ? 153 TYR C CE1 1 
ATOM 2679 C CE2 . TYR C 1 153 ? 114.860 189.041 153.125 1.00 22.34 ? 153 TYR C CE2 1 
ATOM 2680 C CZ  . TYR C 1 153 ? 114.712 188.033 154.051 1.00 24.14 ? 153 TYR C CZ  1 
ATOM 2681 O OH  . TYR C 1 153 ? 115.804 187.596 154.765 1.00 30.74 ? 153 TYR C OH  1 
ATOM 2682 N N   . ARG C 1 154 ? 108.186 190.629 152.577 1.00 33.17 ? 154 ARG C N   1 
ATOM 2683 C CA  . ARG C 1 154 ? 107.071 191.453 152.125 1.00 29.35 ? 154 ARG C CA  1 
ATOM 2684 C C   . ARG C 1 154 ? 107.230 192.859 152.680 1.00 32.92 ? 154 ARG C C   1 
ATOM 2685 O O   . ARG C 1 154 ? 107.289 193.041 153.900 1.00 30.84 ? 154 ARG C O   1 
ATOM 2686 C CB  . ARG C 1 154 ? 105.728 190.857 152.558 1.00 26.79 ? 154 ARG C CB  1 
ATOM 2687 C CG  . ARG C 1 154 ? 104.522 191.653 152.093 1.00 35.23 ? 154 ARG C CG  1 
ATOM 2688 C CD  . ARG C 1 154 ? 103.226 191.025 152.576 1.00 38.18 ? 154 ARG C CD  1 
ATOM 2689 N NE  . ARG C 1 154 ? 102.056 191.732 152.069 1.00 41.54 ? 154 ARG C NE  1 
ATOM 2690 C CZ  . ARG C 1 154 ? 100.803 191.368 152.303 1.00 43.21 ? 154 ARG C CZ  1 
ATOM 2691 N NH1 . ARG C 1 154 ? 100.517 190.305 153.037 1.00 41.26 ? 154 ARG C NH1 1 
ATOM 2692 N NH2 . ARG C 1 154 ? 99.811  192.089 151.787 1.00 38.29 ? 154 ARG C NH2 1 
ATOM 2693 N N   . GLU C 1 155 ? 107.294 193.844 151.782 1.00 40.15 ? 155 GLU C N   1 
ATOM 2694 C CA  . GLU C 1 155 ? 107.337 195.262 152.149 1.00 35.54 ? 155 GLU C CA  1 
ATOM 2695 C C   . GLU C 1 155 ? 108.507 195.573 153.079 1.00 34.27 ? 155 GLU C C   1 
ATOM 2696 O O   . GLU C 1 155 ? 108.390 196.378 154.004 1.00 37.52 ? 155 GLU C O   1 
ATOM 2697 C CB  . GLU C 1 155 ? 106.014 195.707 152.775 1.00 35.18 ? 155 GLU C CB  1 
ATOM 2698 C CG  . GLU C 1 155 ? 104.839 195.704 151.810 1.00 37.54 ? 155 GLU C CG  1 
ATOM 2699 C CD  . GLU C 1 155 ? 103.503 195.809 152.518 1.00 43.67 ? 155 GLU C CD  1 
ATOM 2700 O OE1 . GLU C 1 155 ? 103.301 195.089 153.519 1.00 43.82 ? 155 GLU C OE1 1 
ATOM 2701 O OE2 . GLU C 1 155 ? 102.655 196.611 152.075 1.00 40.89 ? 155 GLU C OE2 1 
ATOM 2702 N N   . ASN C 1 156 ? 109.648 194.941 152.826 1.00 28.51 ? 156 ASN C N   1 
ATOM 2703 C CA  . ASN C 1 156 ? 110.850 195.150 153.622 1.00 29.54 ? 156 ASN C CA  1 
ATOM 2704 C C   . ASN C 1 156 ? 111.750 196.161 152.926 1.00 30.86 ? 156 ASN C C   1 
ATOM 2705 O O   . ASN C 1 156 ? 112.052 196.018 151.737 1.00 40.39 ? 156 ASN C O   1 
ATOM 2706 C CB  . ASN C 1 156 ? 111.597 193.835 153.840 1.00 31.36 ? 156 ASN C CB  1 
ATOM 2707 C CG  . ASN C 1 156 ? 110.722 192.766 154.460 1.00 30.47 ? 156 ASN C CG  1 
ATOM 2708 O OD1 . ASN C 1 156 ? 110.126 191.951 153.756 1.00 38.20 ? 156 ASN C OD1 1 
ATOM 2709 N ND2 . ASN C 1 156 ? 110.636 192.766 155.784 1.00 35.25 ? 156 ASN C ND2 1 
ATOM 2710 N N   . MET C 1 157 ? 112.174 197.180 153.669 1.00 36.16 ? 157 MET C N   1 
ATOM 2711 C CA  . MET C 1 157 ? 113.024 198.245 153.140 1.00 38.76 ? 157 MET C CA  1 
ATOM 2712 C C   . MET C 1 157 ? 114.465 197.945 153.537 1.00 37.37 ? 157 MET C C   1 
ATOM 2713 O O   . MET C 1 157 ? 114.859 198.148 154.689 1.00 41.20 ? 157 MET C O   1 
ATOM 2714 C CB  . MET C 1 157 ? 112.571 199.606 153.657 1.00 36.94 ? 157 MET C CB  1 
ATOM 2715 C CG  . MET C 1 157 ? 112.700 200.730 152.641 1.00 39.70 ? 157 MET C CG  1 
ATOM 2716 S SD  . MET C 1 157 ? 114.414 201.176 152.304 1.00 53.93 ? 157 MET C SD  1 
ATOM 2717 C CE  . MET C 1 157 ? 114.701 202.404 153.574 1.00 40.79 ? 157 MET C CE  1 
ATOM 2718 N N   . TYR C 1 158 ? 115.250 197.463 152.579 1.00 32.10 ? 158 TYR C N   1 
ATOM 2719 C CA  . TYR C 1 158 ? 116.662 197.157 152.791 1.00 23.33 ? 158 TYR C CA  1 
ATOM 2720 C C   . TYR C 1 158 ? 117.483 198.300 152.205 1.00 30.62 ? 158 TYR C C   1 
ATOM 2721 O O   . TYR C 1 158 ? 117.631 198.412 150.986 1.00 40.92 ? 158 TYR C O   1 
ATOM 2722 C CB  . TYR C 1 158 ? 117.029 195.822 152.154 1.00 31.67 ? 158 TYR C CB  1 
ATOM 2723 C CG  . TYR C 1 158 ? 116.701 194.624 153.015 1.00 28.88 ? 158 TYR C CG  1 
ATOM 2724 C CD1 . TYR C 1 158 ? 117.627 194.119 153.917 1.00 26.36 ? 158 TYR C CD1 1 
ATOM 2725 C CD2 . TYR C 1 158 ? 115.465 193.998 152.924 1.00 24.65 ? 158 TYR C CD2 1 
ATOM 2726 C CE1 . TYR C 1 158 ? 117.331 193.025 154.705 1.00 28.95 ? 158 TYR C CE1 1 
ATOM 2727 C CE2 . TYR C 1 158 ? 115.160 192.903 153.708 1.00 26.22 ? 158 TYR C CE2 1 
ATOM 2728 C CZ  . TYR C 1 158 ? 116.097 192.421 154.596 1.00 31.59 ? 158 TYR C CZ  1 
ATOM 2729 O OH  . TYR C 1 158 ? 115.800 191.331 155.379 1.00 31.35 ? 158 TYR C OH  1 
ATOM 2730 N N   . ARG C 1 159 ? 118.017 199.150 153.078 1.00 31.91 ? 159 ARG C N   1 
ATOM 2731 C CA  . ARG C 1 159 ? 118.819 200.298 152.670 1.00 31.02 ? 159 ARG C CA  1 
ATOM 2732 C C   . ARG C 1 159 ? 120.292 199.954 152.857 1.00 34.81 ? 159 ARG C C   1 
ATOM 2733 O O   . ARG C 1 159 ? 120.775 199.867 153.990 1.00 38.90 ? 159 ARG C O   1 
ATOM 2734 C CB  . ARG C 1 159 ? 118.436 201.541 153.470 1.00 34.09 ? 159 ARG C CB  1 
ATOM 2735 C CG  . ARG C 1 159 ? 118.845 202.846 152.809 1.00 35.39 ? 159 ARG C CG  1 
ATOM 2736 C CD  . ARG C 1 159 ? 118.230 204.040 153.516 1.00 31.48 ? 159 ARG C CD  1 
ATOM 2737 N NE  . ARG C 1 159 ? 118.302 205.248 152.703 1.00 35.04 ? 159 ARG C NE  1 
ATOM 2738 C CZ  . ARG C 1 159 ? 117.411 205.585 151.781 1.00 39.92 ? 159 ARG C CZ  1 
ATOM 2739 N NH1 . ARG C 1 159 ? 116.357 204.826 151.528 1.00 39.44 ? 159 ARG C NH1 1 
ATOM 2740 N NH2 . ARG C 1 159 ? 117.579 206.713 151.095 1.00 35.94 ? 159 ARG C NH2 1 
ATOM 2741 N N   . TYR C 1 160 ? 120.997 199.768 151.745 1.00 20.38 ? 160 TYR C N   1 
ATOM 2742 C CA  . TYR C 1 160 ? 122.414 199.426 151.740 1.00 21.14 ? 160 TYR C CA  1 
ATOM 2743 C C   . TYR C 1 160 ? 122.745 198.211 152.612 1.00 24.15 ? 160 TYR C C   1 
ATOM 2744 O O   . TYR C 1 160 ? 123.547 198.311 153.547 1.00 29.58 ? 160 TYR C O   1 
ATOM 2745 C CB  . TYR C 1 160 ? 123.250 200.627 152.161 1.00 25.04 ? 160 TYR C CB  1 
ATOM 2746 C CG  . TYR C 1 160 ? 123.290 201.750 151.149 1.00 28.24 ? 160 TYR C CG  1 
ATOM 2747 C CD1 . TYR C 1 160 ? 122.216 202.619 151.004 1.00 28.18 ? 160 TYR C CD1 1 
ATOM 2748 C CD2 . TYR C 1 160 ? 124.404 201.947 150.346 1.00 30.07 ? 160 TYR C CD2 1 
ATOM 2749 C CE1 . TYR C 1 160 ? 122.250 203.648 150.082 1.00 26.68 ? 160 TYR C CE1 1 
ATOM 2750 C CE2 . TYR C 1 160 ? 124.448 202.973 149.422 1.00 26.95 ? 160 TYR C CE2 1 
ATOM 2751 C CZ  . TYR C 1 160 ? 123.368 203.820 149.293 1.00 25.00 ? 160 TYR C CZ  1 
ATOM 2752 O OH  . TYR C 1 160 ? 123.406 204.844 148.375 1.00 31.55 ? 160 TYR C OH  1 
ATOM 2753 N N   . PRO C 1 161 ? 122.150 197.048 152.337 1.00 20.42 ? 161 PRO C N   1 
ATOM 2754 C CA  . PRO C 1 161 ? 122.523 195.846 153.090 1.00 18.89 ? 161 PRO C CA  1 
ATOM 2755 C C   . PRO C 1 161 ? 123.828 195.245 152.593 1.00 21.09 ? 161 PRO C C   1 
ATOM 2756 O O   . PRO C 1 161 ? 124.107 195.217 151.392 1.00 24.28 ? 161 PRO C O   1 
ATOM 2757 C CB  . PRO C 1 161 ? 121.340 194.900 152.851 1.00 13.88 ? 161 PRO C CB  1 
ATOM 2758 C CG  . PRO C 1 161 ? 120.825 195.287 151.526 1.00 20.22 ? 161 PRO C CG  1 
ATOM 2759 C CD  . PRO C 1 161 ? 121.095 196.762 151.346 1.00 19.05 ? 161 PRO C CD  1 
ATOM 2760 N N   . ASN C 1 162 ? 124.627 194.760 153.545 1.00 20.79 ? 162 ASN C N   1 
ATOM 2761 C CA  . ASN C 1 162 ? 125.941 194.178 153.263 1.00 15.77 ? 162 ASN C CA  1 
ATOM 2762 C C   . ASN C 1 162 ? 126.821 195.155 152.488 1.00 15.47 ? 162 ASN C C   1 
ATOM 2763 O O   . ASN C 1 162 ? 127.536 194.781 151.556 1.00 27.93 ? 162 ASN C O   1 
ATOM 2764 C CB  . ASN C 1 162 ? 125.808 192.849 152.519 1.00 19.21 ? 162 ASN C CB  1 
ATOM 2765 C CG  . ASN C 1 162 ? 124.897 191.870 153.233 1.00 23.01 ? 162 ASN C CG  1 
ATOM 2766 O OD1 . ASN C 1 162 ? 125.118 191.534 154.395 1.00 23.24 ? 162 ASN C OD1 1 
ATOM 2767 N ND2 . ASN C 1 162 ? 123.867 191.404 152.537 1.00 28.10 ? 162 ASN C ND2 1 
ATOM 2768 N N   . GLN C 1 163 ? 126.765 196.425 152.879 1.00 19.47 ? 163 GLN C N   1 
ATOM 2769 C CA  . GLN C 1 163 ? 127.535 197.464 152.212 1.00 23.52 ? 163 GLN C CA  1 
ATOM 2770 C C   . GLN C 1 163 ? 128.974 197.456 152.710 1.00 28.33 ? 163 GLN C C   1 
ATOM 2771 O O   . GLN C 1 163 ? 129.223 197.389 153.918 1.00 32.85 ? 163 GLN C O   1 
ATOM 2772 C CB  . GLN C 1 163 ? 126.898 198.833 152.449 1.00 17.53 ? 163 GLN C CB  1 
ATOM 2773 C CG  . GLN C 1 163 ? 127.185 199.849 151.358 1.00 25.39 ? 163 GLN C CG  1 
ATOM 2774 C CD  . GLN C 1 163 ? 128.260 200.841 151.752 1.00 28.85 ? 163 GLN C CD  1 
ATOM 2775 O OE1 . GLN C 1 163 ? 128.897 200.700 152.796 1.00 29.13 ? 163 GLN C OE1 1 
ATOM 2776 N NE2 . GLN C 1 163 ? 128.466 201.851 150.919 1.00 31.23 ? 163 GLN C NE2 1 
ATOM 2777 N N   . VAL C 1 164 ? 129.919 197.522 151.779 1.00 28.26 ? 164 VAL C N   1 
ATOM 2778 C CA  . VAL C 1 164 ? 131.342 197.560 152.092 1.00 21.81 ? 164 VAL C CA  1 
ATOM 2779 C C   . VAL C 1 164 ? 131.841 198.951 151.728 1.00 29.00 ? 164 VAL C C   1 
ATOM 2780 O O   . VAL C 1 164 ? 132.174 199.221 150.568 1.00 32.82 ? 164 VAL C O   1 
ATOM 2781 C CB  . VAL C 1 164 ? 132.125 196.472 151.350 1.00 31.55 ? 164 VAL C CB  1 
ATOM 2782 C CG1 . VAL C 1 164 ? 133.571 196.452 151.820 1.00 23.51 ? 164 VAL C CG1 1 
ATOM 2783 C CG2 . VAL C 1 164 ? 131.475 195.115 151.554 1.00 30.10 ? 164 VAL C CG2 1 
ATOM 2784 N N   . TYR C 1 165 ? 131.899 199.843 152.717 1.00 34.19 ? 165 TYR C N   1 
ATOM 2785 C CA  . TYR C 1 165 ? 132.421 201.193 152.509 1.00 28.28 ? 165 TYR C CA  1 
ATOM 2786 C C   . TYR C 1 165 ? 133.932 201.150 152.712 1.00 33.76 ? 165 TYR C C   1 
ATOM 2787 O O   . TYR C 1 165 ? 134.465 201.470 153.777 1.00 40.58 ? 165 TYR C O   1 
ATOM 2788 C CB  . TYR C 1 165 ? 131.744 202.185 153.446 1.00 29.51 ? 165 TYR C CB  1 
ATOM 2789 C CG  . TYR C 1 165 ? 131.668 203.587 152.890 1.00 33.82 ? 165 TYR C CG  1 
ATOM 2790 C CD1 . TYR C 1 165 ? 130.625 203.969 152.057 1.00 33.51 ? 165 TYR C CD1 1 
ATOM 2791 C CD2 . TYR C 1 165 ? 132.642 204.529 153.192 1.00 33.01 ? 165 TYR C CD2 1 
ATOM 2792 C CE1 . TYR C 1 165 ? 130.552 205.250 151.544 1.00 32.79 ? 165 TYR C CE1 1 
ATOM 2793 C CE2 . TYR C 1 165 ? 132.579 205.812 152.683 1.00 29.38 ? 165 TYR C CE2 1 
ATOM 2794 C CZ  . TYR C 1 165 ? 131.532 206.167 151.859 1.00 29.63 ? 165 TYR C CZ  1 
ATOM 2795 O OH  . TYR C 1 165 ? 131.464 207.444 151.351 1.00 33.49 ? 165 TYR C OH  1 
ATOM 2796 N N   . TYR C 1 166 ? 134.631 200.740 151.656 1.00 32.05 ? 166 TYR C N   1 
ATOM 2797 C CA  . TYR C 1 166 ? 136.082 200.566 151.691 1.00 29.32 ? 166 TYR C CA  1 
ATOM 2798 C C   . TYR C 1 166 ? 136.723 201.877 151.258 1.00 34.30 ? 166 TYR C C   1 
ATOM 2799 O O   . TYR C 1 166 ? 136.925 202.135 150.071 1.00 41.73 ? 166 TYR C O   1 
ATOM 2800 C CB  . TYR C 1 166 ? 136.501 199.407 150.795 1.00 26.97 ? 166 TYR C CB  1 
ATOM 2801 C CG  . TYR C 1 166 ? 137.945 198.987 150.954 1.00 34.77 ? 166 TYR C CG  1 
ATOM 2802 C CD1 . TYR C 1 166 ? 138.322 198.095 151.948 1.00 32.51 ? 166 TYR C CD1 1 
ATOM 2803 C CD2 . TYR C 1 166 ? 138.931 199.484 150.113 1.00 32.02 ? 166 TYR C CD2 1 
ATOM 2804 C CE1 . TYR C 1 166 ? 139.639 197.706 152.097 1.00 34.92 ? 166 TYR C CE1 1 
ATOM 2805 C CE2 . TYR C 1 166 ? 140.251 199.103 150.256 1.00 31.55 ? 166 TYR C CE2 1 
ATOM 2806 C CZ  . TYR C 1 166 ? 140.599 198.214 151.250 1.00 35.62 ? 166 TYR C CZ  1 
ATOM 2807 O OH  . TYR C 1 166 ? 141.912 197.831 151.397 1.00 38.33 ? 166 TYR C OH  1 
ATOM 2808 N N   . ARG C 1 167 ? 137.051 202.720 152.236 1.00 33.37 ? 167 ARG C N   1 
ATOM 2809 C CA  . ARG C 1 167 ? 137.638 204.037 151.989 1.00 38.24 ? 167 ARG C CA  1 
ATOM 2810 C C   . ARG C 1 167 ? 138.864 204.236 152.875 1.00 40.68 ? 167 ARG C C   1 
ATOM 2811 O O   . ARG C 1 167 ? 138.837 205.026 153.827 1.00 37.52 ? 167 ARG C O   1 
ATOM 2812 C CB  . ARG C 1 167 ? 136.603 205.138 152.229 1.00 30.11 ? 167 ARG C CB  1 
ATOM 2813 C CG  . ARG C 1 167 ? 137.023 206.528 151.769 1.00 30.04 ? 167 ARG C CG  1 
ATOM 2814 C CD  . ARG C 1 167 ? 136.420 206.871 150.423 1.00 39.27 ? 167 ARG C CD  1 
ATOM 2815 N NE  . ARG C 1 167 ? 136.716 208.242 150.023 1.00 36.94 ? 167 ARG C NE  1 
ATOM 2816 C CZ  . ARG C 1 167 ? 135.835 209.233 150.038 1.00 38.27 ? 167 ARG C CZ  1 
ATOM 2817 N NH1 . ARG C 1 167 ? 134.585 209.040 150.427 1.00 41.74 ? 167 ARG C NH1 1 
ATOM 2818 N NH2 . ARG C 1 167 ? 136.216 210.446 149.653 1.00 39.05 ? 167 ARG C NH2 1 
ATOM 2819 N N   . PRO C 1 168 ? 139.959 203.529 152.595 1.00 38.42 ? 168 PRO C N   1 
ATOM 2820 C CA  . PRO C 1 168 ? 141.194 203.769 153.351 1.00 30.85 ? 168 PRO C CA  1 
ATOM 2821 C C   . PRO C 1 168 ? 141.908 205.026 152.882 1.00 33.12 ? 168 PRO C C   1 
ATOM 2822 O O   . PRO C 1 168 ? 141.940 205.343 151.691 1.00 38.90 ? 168 PRO C O   1 
ATOM 2823 C CB  . PRO C 1 168 ? 142.031 202.516 153.067 1.00 30.80 ? 168 PRO C CB  1 
ATOM 2824 C CG  . PRO C 1 168 ? 141.563 202.054 151.748 1.00 31.95 ? 168 PRO C CG  1 
ATOM 2825 C CD  . PRO C 1 168 ? 140.100 202.395 151.666 1.00 31.88 ? 168 PRO C CD  1 
ATOM 2826 N N   . VAL C 1 169 ? 142.483 205.748 153.842 1.00 37.48 ? 169 VAL C N   1 
ATOM 2827 C CA  . VAL C 1 169 ? 143.245 206.961 153.575 1.00 38.75 ? 169 VAL C CA  1 
ATOM 2828 C C   . VAL C 1 169 ? 144.602 206.836 154.254 1.00 42.93 ? 169 VAL C C   1 
ATOM 2829 O O   . VAL C 1 169 ? 144.672 206.570 155.459 1.00 42.92 ? 169 VAL C O   1 
ATOM 2830 C CB  . VAL C 1 169 ? 142.512 208.224 154.066 1.00 30.52 ? 169 VAL C CB  1 
ATOM 2831 C CG1 . VAL C 1 169 ? 143.320 209.468 153.735 1.00 34.99 ? 169 VAL C CG1 1 
ATOM 2832 C CG2 . VAL C 1 169 ? 141.121 208.307 153.455 1.00 31.16 ? 169 VAL C CG2 1 
ATOM 2833 N N   . ASP C 1 170 ? 145.672 207.031 153.482 1.00 34.93 ? 170 ASP C N   1 
ATOM 2834 C CA  . ASP C 1 170 ? 147.042 207.028 153.997 1.00 29.56 ? 170 ASP C CA  1 
ATOM 2835 C C   . ASP C 1 170 ? 147.348 205.741 154.762 1.00 30.61 ? 170 ASP C C   1 
ATOM 2836 O O   . ASP C 1 170 ? 147.900 205.756 155.865 1.00 34.97 ? 170 ASP C O   1 
ATOM 2837 C CB  . ASP C 1 170 ? 147.299 208.256 154.870 1.00 34.32 ? 170 ASP C CB  1 
ATOM 2838 C CG  . ASP C 1 170 ? 147.033 209.557 154.141 1.00 38.06 ? 170 ASP C CG  1 
ATOM 2839 O OD1 . ASP C 1 170 ? 146.689 209.510 152.942 1.00 42.49 ? 170 ASP C OD1 1 
ATOM 2840 O OD2 . ASP C 1 170 ? 147.168 210.629 154.767 1.00 39.16 ? 170 ASP C OD2 1 
ATOM 2841 N N   . GLN C 1 171 ? 146.982 204.611 154.162 1.00 33.72 ? 171 GLN C N   1 
ATOM 2842 C CA  . GLN C 1 171 ? 147.213 203.306 154.774 1.00 34.83 ? 171 GLN C CA  1 
ATOM 2843 C C   . GLN C 1 171 ? 148.641 202.871 154.463 1.00 33.08 ? 171 GLN C C   1 
ATOM 2844 O O   . GLN C 1 171 ? 148.973 202.587 153.309 1.00 30.74 ? 171 GLN C O   1 
ATOM 2845 C CB  . GLN C 1 171 ? 146.195 202.292 154.260 1.00 25.75 ? 171 GLN C CB  1 
ATOM 2846 C CG  . GLN C 1 171 ? 145.828 201.213 155.263 1.00 28.18 ? 171 GLN C CG  1 
ATOM 2847 C CD  . GLN C 1 171 ? 144.776 200.258 154.732 1.00 28.61 ? 171 GLN C CD  1 
ATOM 2848 O OE1 . GLN C 1 171 ? 144.623 200.098 153.521 1.00 34.46 ? 171 GLN C OE1 1 
ATOM 2849 N NE2 . GLN C 1 171 ? 144.044 199.618 155.636 1.00 23.06 ? 171 GLN C NE2 1 
ATOM 2850 N N   . TYR C 1 172 ? 149.487 202.818 155.490 1.00 33.45 ? 172 TYR C N   1 
ATOM 2851 C CA  . TYR C 1 172 ? 150.885 202.404 155.361 1.00 29.28 ? 172 TYR C CA  1 
ATOM 2852 C C   . TYR C 1 172 ? 151.092 201.190 156.259 1.00 35.69 ? 172 TYR C C   1 
ATOM 2853 O O   . TYR C 1 172 ? 151.563 201.312 157.391 1.00 42.15 ? 172 TYR C O   1 
ATOM 2854 C CB  . TYR C 1 172 ? 151.847 203.548 155.731 1.00 34.16 ? 172 TYR C CB  1 
ATOM 2855 C CG  . TYR C 1 172 ? 151.862 204.709 154.762 1.00 33.89 ? 172 TYR C CG  1 
ATOM 2856 C CD1 . TYR C 1 172 ? 150.824 205.631 154.734 1.00 29.80 ? 172 TYR C CD1 1 
ATOM 2857 C CD2 . TYR C 1 172 ? 152.926 204.895 153.890 1.00 35.67 ? 172 TYR C CD2 1 
ATOM 2858 C CE1 . TYR C 1 172 ? 150.838 206.696 153.854 1.00 32.75 ? 172 TYR C CE1 1 
ATOM 2859 C CE2 . TYR C 1 172 ? 152.950 205.958 153.007 1.00 37.83 ? 172 TYR C CE2 1 
ATOM 2860 C CZ  . TYR C 1 172 ? 151.903 206.855 152.993 1.00 40.65 ? 172 TYR C CZ  1 
ATOM 2861 O OH  . TYR C 1 172 ? 151.922 207.915 152.116 1.00 44.24 ? 172 TYR C OH  1 
ATOM 2862 N N   . ASN C 1 173 ? 150.770 200.008 155.743 1.00 27.02 ? 173 ASN C N   1 
ATOM 2863 C CA  . ASN C 1 173 ? 150.848 198.775 156.515 1.00 23.51 ? 173 ASN C CA  1 
ATOM 2864 C C   . ASN C 1 173 ? 151.868 197.835 155.889 1.00 31.96 ? 173 ASN C C   1 
ATOM 2865 O O   . ASN C 1 173 ? 152.007 197.779 154.663 1.00 35.72 ? 173 ASN C O   1 
ATOM 2866 C CB  . ASN C 1 173 ? 149.485 198.087 156.602 1.00 22.96 ? 173 ASN C CB  1 
ATOM 2867 C CG  . ASN C 1 173 ? 148.485 198.878 157.420 1.00 32.44 ? 173 ASN C CG  1 
ATOM 2868 O OD1 . ASN C 1 173 ? 148.859 199.673 158.281 1.00 38.15 ? 173 ASN C OD1 1 
ATOM 2869 N ND2 . ASN C 1 173 ? 147.202 198.662 157.153 1.00 32.79 ? 173 ASN C ND2 1 
ATOM 2870 N N   . ASN C 1 174 ? 152.578 197.098 156.741 1.00 30.72 ? 174 ASN C N   1 
ATOM 2871 C CA  . ASN C 1 174 ? 153.623 196.178 156.306 1.00 20.94 ? 174 ASN C CA  1 
ATOM 2872 C C   . ASN C 1 174 ? 153.401 194.825 156.963 1.00 25.58 ? 174 ASN C C   1 
ATOM 2873 O O   . ASN C 1 174 ? 153.453 194.713 158.192 1.00 36.65 ? 174 ASN C O   1 
ATOM 2874 C CB  . ASN C 1 174 ? 155.012 196.719 156.655 1.00 19.07 ? 174 ASN C CB  1 
ATOM 2875 C CG  . ASN C 1 174 ? 155.418 197.888 155.784 1.00 30.17 ? 174 ASN C CG  1 
ATOM 2876 O OD1 . ASN C 1 174 ? 155.022 199.027 156.031 1.00 38.76 ? 174 ASN C OD1 1 
ATOM 2877 N ND2 . ASN C 1 174 ? 156.216 197.614 154.758 1.00 26.67 ? 174 ASN C ND2 1 
ATOM 2878 N N   . GLN C 1 175 ? 153.153 193.803 156.144 1.00 29.57 ? 175 GLN C N   1 
ATOM 2879 C CA  . GLN C 1 175 ? 153.069 192.413 156.595 1.00 30.86 ? 175 GLN C CA  1 
ATOM 2880 C C   . GLN C 1 175 ? 153.985 191.610 155.676 1.00 29.89 ? 175 GLN C C   1 
ATOM 2881 O O   . GLN C 1 175 ? 153.536 191.034 154.683 1.00 29.59 ? 175 GLN C O   1 
ATOM 2882 C CB  . GLN C 1 175 ? 151.634 191.899 156.565 1.00 22.86 ? 175 GLN C CB  1 
ATOM 2883 C CG  . GLN C 1 175 ? 151.443 190.557 157.251 1.00 24.78 ? 175 GLN C CG  1 
ATOM 2884 C CD  . GLN C 1 175 ? 149.982 190.189 157.414 1.00 26.54 ? 175 GLN C CD  1 
ATOM 2885 O OE1 . GLN C 1 175 ? 149.138 190.577 156.607 1.00 33.43 ? 175 GLN C OE1 1 
ATOM 2886 N NE2 . GLN C 1 175 ? 149.676 189.436 158.463 1.00 27.21 ? 175 GLN C NE2 1 
ATOM 2887 N N   . ASN C 1 176 ? 155.271 191.568 156.015 1.00 26.95 ? 176 ASN C N   1 
ATOM 2888 C CA  . ASN C 1 176 ? 156.287 190.989 155.154 1.00 26.18 ? 176 ASN C CA  1 
ATOM 2889 C C   . ASN C 1 176 ? 156.982 189.829 155.854 1.00 30.01 ? 176 ASN C C   1 
ATOM 2890 O O   . ASN C 1 176 ? 157.164 189.836 157.073 1.00 30.20 ? 176 ASN C O   1 
ATOM 2891 C CB  . ASN C 1 176 ? 157.327 192.039 154.742 1.00 32.05 ? 176 ASN C CB  1 
ATOM 2892 C CG  . ASN C 1 176 ? 156.698 193.264 154.111 1.00 34.20 ? 176 ASN C CG  1 
ATOM 2893 O OD1 . ASN C 1 176 ? 155.745 193.158 153.340 1.00 35.76 ? 176 ASN C OD1 1 
ATOM 2894 N ND2 . ASN C 1 176 ? 157.228 194.436 154.439 1.00 35.64 ? 176 ASN C ND2 1 
ATOM 2895 N N   . THR C 1 177 ? 157.371 188.835 155.062 1.00 40.26 ? 177 THR C N   1 
ATOM 2896 C CA  . THR C 1 177 ? 158.126 187.686 155.543 1.00 36.19 ? 177 THR C CA  1 
ATOM 2897 C C   . THR C 1 177 ? 159.560 187.808 155.048 1.00 30.76 ? 177 THR C C   1 
ATOM 2898 O O   . THR C 1 177 ? 159.799 187.873 153.836 1.00 36.74 ? 177 THR C O   1 
ATOM 2899 C CB  . THR C 1 177 ? 157.503 186.375 155.064 1.00 32.36 ? 177 THR C CB  1 
ATOM 2900 O OG1 . THR C 1 177 ? 156.175 186.255 155.588 1.00 28.76 ? 177 THR C OG1 1 
ATOM 2901 C CG2 . THR C 1 177 ? 158.337 185.194 155.528 1.00 33.83 ? 177 THR C CG2 1 
ATOM 2902 N N   . PHE C 1 178 ? 160.508 187.841 155.980 1.00 28.92 ? 178 PHE C N   1 
ATOM 2903 C CA  . PHE C 1 178 ? 161.924 187.971 155.661 1.00 29.69 ? 178 PHE C CA  1 
ATOM 2904 C C   . PHE C 1 178 ? 162.648 186.716 156.119 1.00 34.55 ? 178 PHE C C   1 
ATOM 2905 O O   . PHE C 1 178 ? 162.587 186.356 157.300 1.00 39.63 ? 178 PHE C O   1 
ATOM 2906 C CB  . PHE C 1 178 ? 162.524 189.212 156.326 1.00 30.28 ? 178 PHE C CB  1 
ATOM 2907 C CG  . PHE C 1 178 ? 162.379 190.466 155.513 1.00 33.96 ? 178 PHE C CG  1 
ATOM 2908 C CD1 . PHE C 1 178 ? 161.236 191.242 155.611 1.00 33.69 ? 178 PHE C CD1 1 
ATOM 2909 C CD2 . PHE C 1 178 ? 163.385 190.867 154.651 1.00 36.35 ? 178 PHE C CD2 1 
ATOM 2910 C CE1 . PHE C 1 178 ? 161.100 192.395 154.863 1.00 35.22 ? 178 PHE C CE1 1 
ATOM 2911 C CE2 . PHE C 1 178 ? 163.254 192.021 153.901 1.00 38.84 ? 178 PHE C CE2 1 
ATOM 2912 C CZ  . PHE C 1 178 ? 162.109 192.786 154.007 1.00 39.11 ? 178 PHE C CZ  1 
ATOM 2913 N N   . VAL C 1 179 ? 163.329 186.053 155.189 1.00 37.15 ? 179 VAL C N   1 
ATOM 2914 C CA  . VAL C 1 179 ? 164.124 184.868 155.483 1.00 30.20 ? 179 VAL C CA  1 
ATOM 2915 C C   . VAL C 1 179 ? 165.535 185.117 154.975 1.00 26.14 ? 179 VAL C C   1 
ATOM 2916 O O   . VAL C 1 179 ? 165.746 185.265 153.766 1.00 34.27 ? 179 VAL C O   1 
ATOM 2917 C CB  . VAL C 1 179 ? 163.534 183.599 154.845 1.00 29.16 ? 179 VAL C CB  1 
ATOM 2918 C CG1 . VAL C 1 179 ? 164.525 182.450 154.936 1.00 29.18 ? 179 VAL C CG1 1 
ATOM 2919 C CG2 . VAL C 1 179 ? 162.227 183.230 155.523 1.00 28.26 ? 179 VAL C CG2 1 
ATOM 2920 N N   . HIS C 1 180 ? 166.496 185.165 155.893 1.00 30.99 ? 180 HIS C N   1 
ATOM 2921 C CA  . HIS C 1 180 ? 167.903 185.358 155.562 1.00 35.83 ? 180 HIS C CA  1 
ATOM 2922 C C   . HIS C 1 180 ? 168.670 184.136 156.044 1.00 34.92 ? 180 HIS C C   1 
ATOM 2923 O O   . HIS C 1 180 ? 168.884 183.966 157.249 1.00 41.11 ? 180 HIS C O   1 
ATOM 2924 C CB  . HIS C 1 180 ? 168.448 186.639 156.193 1.00 37.66 ? 180 HIS C CB  1 
ATOM 2925 C CG  . HIS C 1 180 ? 168.170 187.872 155.392 1.00 37.42 ? 180 HIS C CG  1 
ATOM 2926 N ND1 . HIS C 1 180 ? 169.051 188.930 155.325 1.00 35.05 ? 180 HIS C ND1 1 
ATOM 2927 C CD2 . HIS C 1 180 ? 167.111 188.215 154.622 1.00 38.81 ? 180 HIS C CD2 1 
ATOM 2928 C CE1 . HIS C 1 180 ? 168.545 189.873 154.550 1.00 41.71 ? 180 HIS C CE1 1 
ATOM 2929 N NE2 . HIS C 1 180 ? 167.369 189.463 154.110 1.00 38.77 ? 180 HIS C NE2 1 
ATOM 2930 N N   . ASP C 1 181 ? 169.081 183.287 155.105 1.00 45.73 ? 181 ASP C N   1 
ATOM 2931 C CA  . ASP C 1 181 ? 169.801 182.059 155.412 1.00 45.25 ? 181 ASP C CA  1 
ATOM 2932 C C   . ASP C 1 181 ? 171.169 182.113 154.750 1.00 44.49 ? 181 ASP C C   1 
ATOM 2933 O O   . ASP C 1 181 ? 171.261 182.238 153.524 1.00 43.21 ? 181 ASP C O   1 
ATOM 2934 C CB  . ASP C 1 181 ? 169.021 180.831 154.940 1.00 41.27 ? 181 ASP C CB  1 
ATOM 2935 C CG  . ASP C 1 181 ? 169.579 179.537 155.495 1.00 47.44 ? 181 ASP C CG  1 
ATOM 2936 O OD1 . ASP C 1 181 ? 169.445 179.306 156.714 1.00 50.55 ? 181 ASP C OD1 1 
ATOM 2937 O OD2 . ASP C 1 181 ? 170.153 178.752 154.712 1.00 46.95 ? 181 ASP C OD2 1 
ATOM 2938 N N   . CYS C 1 182 ? 172.222 182.012 155.561 1.00 41.99 ? 182 CYS C N   1 
ATOM 2939 C CA  . CYS C 1 182 ? 173.602 181.982 155.075 1.00 37.09 ? 182 CYS C CA  1 
ATOM 2940 C C   . CYS C 1 182 ? 173.926 183.210 154.227 1.00 39.66 ? 182 CYS C C   1 
ATOM 2941 O O   . CYS C 1 182 ? 174.552 183.112 153.171 1.00 43.22 ? 182 CYS C O   1 
ATOM 2942 C CB  . CYS C 1 182 ? 173.876 180.696 154.296 1.00 40.47 ? 182 CYS C CB  1 
ATOM 2943 S SG  . CYS C 1 182 ? 173.901 179.217 155.325 1.00 63.20 ? 182 CYS C SG  1 
ATOM 2944 N N   . VAL C 1 183 ? 173.499 184.376 154.696 1.00 36.16 ? 183 VAL C N   1 
ATOM 2945 C CA  . VAL C 1 183 ? 173.732 185.635 154.001 1.00 33.28 ? 183 VAL C CA  1 
ATOM 2946 C C   . VAL C 1 183 ? 174.917 186.338 154.643 1.00 24.08 ? 183 VAL C C   1 
ATOM 2947 O O   . VAL C 1 183 ? 175.186 186.184 155.840 1.00 36.03 ? 183 VAL C O   1 
ATOM 2948 C CB  . VAL C 1 183 ? 172.473 186.528 154.022 1.00 33.36 ? 183 VAL C CB  1 
ATOM 2949 C CG1 . VAL C 1 183 ? 172.768 187.886 153.401 1.00 35.78 ? 183 VAL C CG1 1 
ATOM 2950 C CG2 . VAL C 1 183 ? 171.328 185.844 153.295 1.00 30.11 ? 183 VAL C CG2 1 
ATOM 2951 N N   . ASN C 1 184 ? 175.635 187.119 153.833 1.00 27.82 ? 184 ASN C N   1 
ATOM 2952 C CA  . ASN C 1 184 ? 176.793 187.891 154.286 1.00 35.27 ? 184 ASN C CA  1 
ATOM 2953 C C   . ASN C 1 184 ? 177.853 186.994 154.921 1.00 32.20 ? 184 ASN C C   1 
ATOM 2954 O O   . ASN C 1 184 ? 178.443 187.329 155.950 1.00 29.28 ? 184 ASN C O   1 
ATOM 2955 C CB  . ASN C 1 184 ? 176.372 189.003 155.251 1.00 33.08 ? 184 ASN C CB  1 
ATOM 2956 C CG  . ASN C 1 184 ? 175.543 190.079 154.576 1.00 32.32 ? 184 ASN C CG  1 
ATOM 2957 O OD1 . ASN C 1 184 ? 174.998 189.869 153.493 1.00 34.08 ? 184 ASN C OD1 1 
ATOM 2958 N ND2 . ASN C 1 184 ? 175.446 191.239 155.213 1.00 34.73 ? 184 ASN C ND2 1 
ATOM 2959 N N   . ILE C 1 185 ? 178.098 185.843 154.303 1.00 30.52 ? 185 ILE C N   1 
ATOM 2960 C CA  . ILE C 1 185 ? 179.142 184.927 154.747 1.00 30.93 ? 185 ILE C CA  1 
ATOM 2961 C C   . ILE C 1 185 ? 180.439 185.311 154.047 1.00 27.44 ? 185 ILE C C   1 
ATOM 2962 O O   . ILE C 1 185 ? 180.503 185.340 152.813 1.00 31.09 ? 185 ILE C O   1 
ATOM 2963 C CB  . ILE C 1 185 ? 178.767 183.468 154.454 1.00 30.18 ? 185 ILE C CB  1 
ATOM 2964 C CG1 . ILE C 1 185 ? 177.555 183.051 155.289 1.00 30.01 ? 185 ILE C CG1 1 
ATOM 2965 C CG2 . ILE C 1 185 ? 179.952 182.553 154.723 1.00 27.74 ? 185 ILE C CG2 1 
ATOM 2966 C CD1 . ILE C 1 185 ? 177.287 181.563 155.277 1.00 30.44 ? 185 ILE C CD1 1 
ATOM 2967 N N   . THR C 1 186 ? 181.471 185.606 154.832 1.00 27.62 ? 186 THR C N   1 
ATOM 2968 C CA  . THR C 1 186 ? 182.738 186.087 154.297 1.00 33.30 ? 186 THR C CA  1 
ATOM 2969 C C   . THR C 1 186 ? 183.885 185.262 154.859 1.00 30.62 ? 186 THR C C   1 
ATOM 2970 O O   . THR C 1 186 ? 184.003 185.102 156.078 1.00 24.31 ? 186 THR C O   1 
ATOM 2971 C CB  . THR C 1 186 ? 182.950 187.570 154.625 1.00 34.76 ? 186 THR C CB  1 
ATOM 2972 O OG1 . THR C 1 186 ? 181.847 188.333 154.121 1.00 42.10 ? 186 THR C OG1 1 
ATOM 2973 C CG2 . THR C 1 186 ? 184.240 188.076 153.997 1.00 33.05 ? 186 THR C CG2 1 
ATOM 2974 N N   . VAL C 1 187 ? 184.725 184.743 153.967 1.00 28.27 ? 187 VAL C N   1 
ATOM 2975 C CA  . VAL C 1 187 ? 185.980 184.094 154.327 1.00 27.56 ? 187 VAL C CA  1 
ATOM 2976 C C   . VAL C 1 187 ? 187.067 184.855 153.581 1.00 26.51 ? 187 VAL C C   1 
ATOM 2977 O O   . VAL C 1 187 ? 187.297 184.619 152.389 1.00 36.66 ? 187 VAL C O   1 
ATOM 2978 C CB  . VAL C 1 187 ? 185.993 182.603 153.975 1.00 28.93 ? 187 VAL C CB  1 
ATOM 2979 C CG1 . VAL C 1 187 ? 187.227 181.934 154.554 1.00 29.77 ? 187 VAL C CG1 1 
ATOM 2980 C CG2 . VAL C 1 187 ? 184.728 181.925 154.480 1.00 30.31 ? 187 VAL C CG2 1 
ATOM 2981 N N   . LYS C 1 188 ? 187.742 185.770 154.274 1.00 23.75 ? 188 LYS C N   1 
ATOM 2982 C CA  . LYS C 1 188 ? 188.621 186.729 153.624 1.00 29.88 ? 188 LYS C CA  1 
ATOM 2983 C C   . LYS C 1 188 ? 189.934 186.838 154.386 1.00 28.73 ? 188 LYS C C   1 
ATOM 2984 O O   . LYS C 1 188 ? 189.990 186.604 155.594 1.00 41.12 ? 188 LYS C O   1 
ATOM 2985 C CB  . LYS C 1 188 ? 187.951 188.109 153.525 1.00 29.75 ? 188 LYS C CB  1 
ATOM 2986 C CG  . LYS C 1 188 ? 188.658 189.106 152.620 1.00 28.86 ? 188 LYS C CG  1 
ATOM 2987 C CD  . LYS C 1 188 ? 188.025 190.484 152.719 1.00 27.86 ? 188 LYS C CD  1 
ATOM 2988 C CE  . LYS C 1 188 ? 188.753 191.491 151.843 1.00 38.02 ? 188 LYS C CE  1 
ATOM 2989 N NZ  . LYS C 1 188 ? 188.282 192.882 152.084 1.00 31.08 ? 188 LYS C NZ  1 
ATOM 2990 N N   . GLN C 1 189 ? 190.993 187.186 153.658 1.00 38.59 ? 189 GLN C N   1 
ATOM 2991 C CA  . GLN C 1 189 ? 192.278 187.552 154.246 1.00 40.40 ? 189 GLN C CA  1 
ATOM 2992 C C   . GLN C 1 189 ? 192.686 188.893 153.656 1.00 42.87 ? 189 GLN C C   1 
ATOM 2993 O O   . GLN C 1 189 ? 193.007 188.981 152.465 1.00 47.50 ? 189 GLN C O   1 
ATOM 2994 C CB  . GLN C 1 189 ? 193.341 186.484 153.985 1.00 40.37 ? 189 GLN C CB  1 
ATOM 2995 C CG  . GLN C 1 189 ? 193.209 185.772 152.651 1.00 44.91 ? 189 GLN C CG  1 
ATOM 2996 C CD  . GLN C 1 189 ? 194.205 184.640 152.497 1.00 46.36 ? 189 GLN C CD  1 
ATOM 2997 O OE1 . GLN C 1 189 ? 195.033 184.404 153.376 1.00 46.81 ? 189 GLN C OE1 1 
ATOM 2998 N NE2 . GLN C 1 189 ? 194.131 183.933 151.375 1.00 41.98 ? 189 GLN C NE2 1 
ATOM 2999 N N   . HIS C 1 190 ? 192.672 189.937 154.480 1.00 35.85 ? 190 HIS C N   1 
ATOM 3000 C CA  . HIS C 1 190 ? 192.918 191.299 154.031 1.00 37.93 ? 190 HIS C CA  1 
ATOM 3001 C C   . HIS C 1 190 ? 194.152 191.864 154.717 1.00 33.62 ? 190 HIS C C   1 
ATOM 3002 O O   . HIS C 1 190 ? 194.346 191.680 155.923 1.00 42.85 ? 190 HIS C O   1 
ATOM 3003 C CB  . HIS C 1 190 ? 191.706 192.195 154.309 1.00 42.39 ? 190 HIS C CB  1 
ATOM 3004 C CG  . HIS C 1 190 ? 191.871 193.601 153.828 1.00 40.73 ? 190 HIS C CG  1 
ATOM 3005 N ND1 . HIS C 1 190 ? 192.578 193.920 152.688 1.00 44.85 ? 190 HIS C ND1 1 
ATOM 3006 C CD2 . HIS C 1 190 ? 191.416 194.774 154.328 1.00 41.50 ? 190 HIS C CD2 1 
ATOM 3007 C CE1 . HIS C 1 190 ? 192.556 195.229 152.510 1.00 44.48 ? 190 HIS C CE1 1 
ATOM 3008 N NE2 . HIS C 1 190 ? 191.857 195.771 153.490 1.00 42.65 ? 190 HIS C NE2 1 
ATOM 3009 N N   . THR C 1 191 ? 194.986 192.553 153.941 1.00 34.10 ? 191 THR C N   1 
ATOM 3010 C CA  . THR C 1 191 ? 196.206 193.167 154.446 1.00 41.72 ? 191 THR C CA  1 
ATOM 3011 C C   . THR C 1 191 ? 196.278 194.606 153.959 1.00 42.88 ? 191 THR C C   1 
ATOM 3012 O O   . THR C 1 191 ? 196.075 194.873 152.771 1.00 44.24 ? 191 THR C O   1 
ATOM 3013 C CB  . THR C 1 191 ? 197.450 192.397 153.988 1.00 41.33 ? 191 THR C CB  1 
ATOM 3014 O OG1 . THR C 1 191 ? 197.396 191.057 154.489 1.00 42.79 ? 191 THR C OG1 1 
ATOM 3015 C CG2 . THR C 1 191 ? 198.714 193.070 154.503 1.00 39.36 ? 191 THR C CG2 1 
ATOM 3016 N N   . VAL C 1 192 ? 196.567 195.527 154.875 1.00 40.34 ? 192 VAL C N   1 
ATOM 3017 C CA  . VAL C 1 192 ? 196.747 196.936 154.554 1.00 37.48 ? 192 VAL C CA  1 
ATOM 3018 C C   . VAL C 1 192 ? 198.175 197.315 154.914 1.00 39.45 ? 192 VAL C C   1 
ATOM 3019 O O   . VAL C 1 192 ? 198.602 197.129 156.061 1.00 46.10 ? 192 VAL C O   1 
ATOM 3020 C CB  . VAL C 1 192 ? 195.740 197.828 155.297 1.00 41.29 ? 192 VAL C CB  1 
ATOM 3021 C CG1 . VAL C 1 192 ? 195.902 199.278 154.869 1.00 45.82 ? 192 VAL C CG1 1 
ATOM 3022 C CG2 . VAL C 1 192 ? 194.321 197.347 155.046 1.00 39.03 ? 192 VAL C CG2 1 
ATOM 3023 N N   . THR C 1 193 ? 198.912 197.842 153.941 1.00 48.16 ? 193 THR C N   1 
ATOM 3024 C CA  . THR C 1 193 ? 200.295 198.256 154.133 1.00 50.71 ? 193 THR C CA  1 
ATOM 3025 C C   . THR C 1 193 ? 200.415 199.747 153.862 1.00 49.11 ? 193 THR C C   1 
ATOM 3026 O O   . THR C 1 193 ? 200.031 200.221 152.787 1.00 49.10 ? 193 THR C O   1 
ATOM 3027 C CB  . THR C 1 193 ? 201.242 197.476 153.215 1.00 52.40 ? 193 THR C CB  1 
ATOM 3028 O OG1 . THR C 1 193 ? 201.082 196.070 153.442 1.00 48.44 ? 193 THR C OG1 1 
ATOM 3029 C CG2 . THR C 1 193 ? 202.687 197.869 153.485 1.00 51.56 ? 193 THR C CG2 1 
ATOM 3030 N N   . THR C 1 194 ? 200.948 200.483 154.838 1.00 46.47 ? 194 THR C N   1 
ATOM 3031 C CA  . THR C 1 194 ? 201.174 201.926 154.712 1.00 49.09 ? 194 THR C CA  1 
ATOM 3032 C C   . THR C 1 194 ? 202.533 202.226 155.341 1.00 50.70 ? 194 THR C C   1 
ATOM 3033 O O   . THR C 1 194 ? 202.631 202.473 156.546 1.00 52.14 ? 194 THR C O   1 
ATOM 3034 C CB  . THR C 1 194 ? 200.058 202.728 155.370 1.00 49.30 ? 194 THR C CB  1 
ATOM 3035 O OG1 . THR C 1 194 ? 198.788 202.261 154.895 1.00 46.94 ? 194 THR C OG1 1 
ATOM 3036 C CG2 . THR C 1 194 ? 200.202 204.206 155.040 1.00 47.45 ? 194 THR C CG2 1 
ATOM 3037 N N   . THR C 1 195 ? 203.576 202.202 154.518 1.00 49.04 ? 195 THR C N   1 
ATOM 3038 C CA  . THR C 1 195 ? 204.941 202.439 154.965 1.00 53.61 ? 195 THR C CA  1 
ATOM 3039 C C   . THR C 1 195 ? 205.452 203.742 154.367 1.00 52.35 ? 195 THR C C   1 
ATOM 3040 O O   . THR C 1 195 ? 205.359 203.952 153.152 1.00 49.17 ? 195 THR C O   1 
ATOM 3041 C CB  . THR C 1 195 ? 205.860 201.282 154.569 1.00 50.40 ? 195 THR C CB  1 
ATOM 3042 O OG1 . THR C 1 195 ? 205.344 200.056 155.101 1.00 52.03 ? 195 THR C OG1 1 
ATOM 3043 C CG2 . THR C 1 195 ? 207.263 201.511 155.110 1.00 51.02 ? 195 THR C CG2 1 
ATOM 3044 N N   . THR C 1 196 ? 205.987 204.610 155.219 1.00 53.59 ? 196 THR C N   1 
ATOM 3045 C CA  . THR C 1 196 ? 206.537 205.893 154.804 1.00 52.66 ? 196 THR C CA  1 
ATOM 3046 C C   . THR C 1 196 ? 208.035 205.936 155.062 1.00 54.50 ? 196 THR C C   1 
ATOM 3047 O O   . THR C 1 196 ? 208.476 205.728 156.197 1.00 53.08 ? 196 THR C O   1 
ATOM 3048 C CB  . THR C 1 196 ? 205.870 207.048 155.555 1.00 55.14 ? 196 THR C CB  1 
ATOM 3049 O OG1 . THR C 1 196 ? 204.444 206.913 155.473 1.00 54.11 ? 196 THR C OG1 1 
ATOM 3050 C CG2 . THR C 1 196 ? 206.282 208.383 154.953 1.00 55.02 ? 196 THR C CG2 1 
ATOM 3051 N N   . LYS C 1 197 ? 208.801 206.216 154.006 1.00 65.56 ? 197 LYS C N   1 
ATOM 3052 C CA  . LYS C 1 197 ? 210.267 206.304 154.030 1.00 65.81 ? 197 LYS C CA  1 
ATOM 3053 C C   . LYS C 1 197 ? 210.884 205.173 154.853 1.00 65.64 ? 197 LYS C C   1 
ATOM 3054 O O   . LYS C 1 197 ? 211.745 205.381 155.711 1.00 64.86 ? 197 LYS C O   1 
ATOM 3055 C CB  . LYS C 1 197 ? 210.758 207.677 154.509 1.00 64.87 ? 197 LYS C CB  1 
ATOM 3056 C CG  . LYS C 1 197 ? 210.251 208.148 155.867 1.00 62.96 ? 197 LYS C CG  1 
ATOM 3057 C CD  . LYS C 1 197 ? 210.854 209.490 156.244 1.00 64.76 ? 197 LYS C CD  1 
ATOM 3058 C CE  . LYS C 1 197 ? 210.273 210.614 155.400 1.00 65.57 ? 197 LYS C CE  1 
ATOM 3059 N NZ  . LYS C 1 197 ? 208.800 210.741 155.579 1.00 63.84 ? 197 LYS C NZ  1 
ATOM 3060 N N   . GLY C 1 198 ? 210.437 203.952 154.571 1.00 60.50 ? 198 GLY C N   1 
ATOM 3061 C CA  . GLY C 1 198 ? 211.009 202.777 155.199 1.00 59.33 ? 198 GLY C CA  1 
ATOM 3062 C C   . GLY C 1 198 ? 212.316 202.373 154.550 1.00 59.91 ? 198 GLY C C   1 
ATOM 3063 O O   . GLY C 1 198 ? 212.340 201.993 153.376 1.00 61.04 ? 198 GLY C O   1 
ATOM 3064 N N   . GLU C 1 199 ? 213.411 202.450 155.301 1.00 58.39 ? 199 GLU C N   1 
ATOM 3065 C CA  . GLU C 1 199 ? 214.747 202.220 154.769 1.00 60.87 ? 199 GLU C CA  1 
ATOM 3066 C C   . GLU C 1 199 ? 215.343 200.955 155.370 1.00 60.52 ? 199 GLU C C   1 
ATOM 3067 O O   . GLU C 1 199 ? 215.366 200.796 156.596 1.00 59.17 ? 199 GLU C O   1 
ATOM 3068 C CB  . GLU C 1 199 ? 215.658 203.418 155.055 1.00 62.13 ? 199 GLU C CB  1 
ATOM 3069 C CG  . GLU C 1 199 ? 215.236 204.698 154.354 1.00 63.39 ? 199 GLU C CG  1 
ATOM 3070 C CD  . GLU C 1 199 ? 216.034 205.903 154.812 1.00 64.46 ? 199 GLU C CD  1 
ATOM 3071 O OE1 . GLU C 1 199 ? 216.549 205.879 155.949 1.00 61.74 ? 199 GLU C OE1 1 
ATOM 3072 O OE2 . GLU C 1 199 ? 216.145 206.874 154.034 1.00 64.33 ? 199 GLU C OE2 1 
ATOM 3073 N N   . ASN C 1 200 ? 215.827 200.065 154.500 1.00 68.57 ? 200 ASN C N   1 
ATOM 3074 C CA  . ASN C 1 200 ? 216.559 198.862 154.904 1.00 68.12 ? 200 ASN C CA  1 
ATOM 3075 C C   . ASN C 1 200 ? 215.749 197.996 155.865 1.00 63.31 ? 200 ASN C C   1 
ATOM 3076 O O   . ASN C 1 200 ? 216.283 197.443 156.829 1.00 63.03 ? 200 ASN C O   1 
ATOM 3077 C CB  . ASN C 1 200 ? 217.914 199.225 155.516 1.00 65.91 ? 200 ASN C CB  1 
ATOM 3078 C CG  . ASN C 1 200 ? 218.751 200.098 154.602 1.00 68.81 ? 200 ASN C CG  1 
ATOM 3079 O OD1 . ASN C 1 200 ? 218.720 201.325 154.695 1.00 69.14 ? 200 ASN C OD1 1 
ATOM 3080 N ND2 . ASN C 1 200 ? 219.506 199.466 153.710 1.00 67.93 ? 200 ASN C ND2 1 
ATOM 3081 N N   . PHE C 1 201 ? 214.453 197.862 155.599 1.00 51.68 ? 201 PHE C N   1 
ATOM 3082 C CA  . PHE C 1 201 ? 213.571 197.080 156.451 1.00 54.38 ? 201 PHE C CA  1 
ATOM 3083 C C   . PHE C 1 201 ? 212.953 195.933 155.663 1.00 52.48 ? 201 PHE C C   1 
ATOM 3084 O O   . PHE C 1 201 ? 212.722 196.038 154.455 1.00 53.11 ? 201 PHE C O   1 
ATOM 3085 C CB  . PHE C 1 201 ? 212.476 197.961 157.079 1.00 55.05 ? 201 PHE C CB  1 
ATOM 3086 C CG  . PHE C 1 201 ? 211.224 198.082 156.252 1.00 56.16 ? 201 PHE C CG  1 
ATOM 3087 C CD1 . PHE C 1 201 ? 211.093 199.093 155.316 1.00 52.21 ? 201 PHE C CD1 1 
ATOM 3088 C CD2 . PHE C 1 201 ? 210.163 197.206 156.434 1.00 54.54 ? 201 PHE C CD2 1 
ATOM 3089 C CE1 . PHE C 1 201 ? 209.941 199.216 154.563 1.00 50.84 ? 201 PHE C CE1 1 
ATOM 3090 C CE2 . PHE C 1 201 ? 209.011 197.323 155.682 1.00 51.94 ? 201 PHE C CE2 1 
ATOM 3091 C CZ  . PHE C 1 201 ? 208.900 198.329 154.746 1.00 52.23 ? 201 PHE C CZ  1 
ATOM 3092 N N   . THR C 1 202 ? 212.690 194.834 156.362 1.00 52.32 ? 202 THR C N   1 
ATOM 3093 C CA  . THR C 1 202 ? 212.106 193.636 155.773 1.00 53.03 ? 202 THR C CA  1 
ATOM 3094 C C   . THR C 1 202 ? 210.675 193.477 156.265 1.00 50.78 ? 202 THR C C   1 
ATOM 3095 O O   . THR C 1 202 ? 210.420 193.526 157.472 1.00 53.86 ? 202 THR C O   1 
ATOM 3096 C CB  . THR C 1 202 ? 212.927 192.394 156.127 1.00 50.28 ? 202 THR C CB  1 
ATOM 3097 O OG1 . THR C 1 202 ? 214.266 192.548 155.639 1.00 53.98 ? 202 THR C OG1 1 
ATOM 3098 C CG2 . THR C 1 202 ? 212.307 191.150 155.509 1.00 50.97 ? 202 THR C CG2 1 
ATOM 3099 N N   . GLU C 1 203 ? 209.750 193.289 155.330 1.00 51.17 ? 203 GLU C N   1 
ATOM 3100 C CA  . GLU C 1 203 ? 208.338 193.104 155.637 1.00 48.56 ? 203 GLU C CA  1 
ATOM 3101 C C   . GLU C 1 203 ? 207.920 191.690 155.261 1.00 50.88 ? 203 GLU C C   1 
ATOM 3102 O O   . GLU C 1 203 ? 208.121 191.262 154.120 1.00 53.33 ? 203 GLU C O   1 
ATOM 3103 C CB  . GLU C 1 203 ? 207.478 194.126 154.890 1.00 52.89 ? 203 GLU C CB  1 
ATOM 3104 C CG  . GLU C 1 203 ? 205.998 194.042 155.217 1.00 56.11 ? 203 GLU C CG  1 
ATOM 3105 C CD  . GLU C 1 203 ? 205.183 195.097 154.497 1.00 55.62 ? 203 GLU C CD  1 
ATOM 3106 O OE1 . GLU C 1 203 ? 205.769 195.872 153.714 1.00 53.41 ? 203 GLU C OE1 1 
ATOM 3107 O OE2 . GLU C 1 203 ? 203.955 195.149 154.715 1.00 55.09 ? 203 GLU C OE2 1 
ATOM 3108 N N   . THR C 1 204 ? 207.344 190.970 156.220 1.00 52.68 ? 204 THR C N   1 
ATOM 3109 C CA  . THR C 1 204 ? 206.871 189.610 156.002 1.00 54.63 ? 204 THR C CA  1 
ATOM 3110 C C   . THR C 1 204 ? 205.408 189.519 156.410 1.00 51.93 ? 204 THR C C   1 
ATOM 3111 O O   . THR C 1 204 ? 205.062 189.812 157.558 1.00 57.57 ? 204 THR C O   1 
ATOM 3112 C CB  . THR C 1 204 ? 207.704 188.596 156.795 1.00 53.25 ? 204 THR C CB  1 
ATOM 3113 O OG1 . THR C 1 204 ? 209.080 188.700 156.409 1.00 55.87 ? 204 THR C OG1 1 
ATOM 3114 C CG2 . THR C 1 204 ? 207.214 187.182 156.528 1.00 52.63 ? 204 THR C CG2 1 
ATOM 3115 N N   . ASP C 1 205 ? 204.560 189.098 155.473 1.00 44.95 ? 205 ASP C N   1 
ATOM 3116 C CA  . ASP C 1 205 ? 203.121 188.968 155.695 1.00 45.63 ? 205 ASP C CA  1 
ATOM 3117 C C   . ASP C 1 205 ? 202.688 187.597 155.186 1.00 48.71 ? 205 ASP C C   1 
ATOM 3118 O O   . ASP C 1 205 ? 202.462 187.416 153.986 1.00 55.01 ? 205 ASP C O   1 
ATOM 3119 C CB  . ASP C 1 205 ? 202.349 190.083 154.994 1.00 51.54 ? 205 ASP C CB  1 
ATOM 3120 C CG  . ASP C 1 205 ? 202.540 191.436 155.655 1.00 56.86 ? 205 ASP C CG  1 
ATOM 3121 O OD1 . ASP C 1 205 ? 203.027 191.480 156.802 1.00 54.93 ? 205 ASP C OD1 1 
ATOM 3122 O OD2 . ASP C 1 205 ? 202.202 192.459 155.023 1.00 56.78 ? 205 ASP C OD2 1 
ATOM 3123 N N   . ILE C 1 206 ? 202.576 186.634 156.096 1.00 41.34 ? 206 ILE C N   1 
ATOM 3124 C CA  . ILE C 1 206 ? 202.157 185.276 155.769 1.00 44.19 ? 206 ILE C CA  1 
ATOM 3125 C C   . ILE C 1 206 ? 200.814 185.017 156.436 1.00 39.49 ? 206 ILE C C   1 
ATOM 3126 O O   . ILE C 1 206 ? 200.674 185.188 157.653 1.00 43.70 ? 206 ILE C O   1 
ATOM 3127 C CB  . ILE C 1 206 ? 203.201 184.238 156.215 1.00 37.28 ? 206 ILE C CB  1 
ATOM 3128 C CG1 . ILE C 1 206 ? 204.569 184.564 155.613 1.00 41.77 ? 206 ILE C CG1 1 
ATOM 3129 C CG2 . ILE C 1 206 ? 202.762 182.838 155.814 1.00 33.21 ? 206 ILE C CG2 1 
ATOM 3130 C CD1 . ILE C 1 206 ? 205.656 183.593 156.015 1.00 42.50 ? 206 ILE C CD1 1 
ATOM 3131 N N   . LYS C 1 207 ? 199.828 184.609 155.639 1.00 36.66 ? 207 LYS C N   1 
ATOM 3132 C CA  . LYS C 1 207 ? 198.489 184.281 156.129 1.00 35.07 ? 207 LYS C CA  1 
ATOM 3133 C C   . LYS C 1 207 ? 198.125 182.911 155.565 1.00 37.98 ? 207 LYS C C   1 
ATOM 3134 O O   . LYS C 1 207 ? 197.535 182.809 154.486 1.00 43.11 ? 207 LYS C O   1 
ATOM 3135 C CB  . LYS C 1 207 ? 197.479 185.353 155.734 1.00 40.96 ? 207 LYS C CB  1 
ATOM 3136 C CG  . LYS C 1 207 ? 197.708 186.691 156.412 1.00 41.93 ? 207 LYS C CG  1 
ATOM 3137 C CD  . LYS C 1 207 ? 196.620 187.686 156.057 1.00 39.80 ? 207 LYS C CD  1 
ATOM 3138 C CE  . LYS C 1 207 ? 196.792 188.977 156.836 1.00 40.21 ? 207 LYS C CE  1 
ATOM 3139 N NZ  . LYS C 1 207 ? 197.971 189.753 156.362 1.00 41.69 ? 207 LYS C NZ  1 
ATOM 3140 N N   . MET C 1 208 ? 198.482 181.861 156.297 1.00 49.38 ? 208 MET C N   1 
ATOM 3141 C CA  . MET C 1 208 ? 198.106 180.513 155.900 1.00 46.82 ? 208 MET C CA  1 
ATOM 3142 C C   . MET C 1 208 ? 196.612 180.305 156.110 1.00 42.45 ? 208 MET C C   1 
ATOM 3143 O O   . MET C 1 208 ? 196.050 180.717 157.127 1.00 51.23 ? 208 MET C O   1 
ATOM 3144 C CB  . MET C 1 208 ? 198.887 179.481 156.714 1.00 47.70 ? 208 MET C CB  1 
ATOM 3145 C CG  . MET C 1 208 ? 200.379 179.461 156.430 1.00 51.54 ? 208 MET C CG  1 
ATOM 3146 S SD  . MET C 1 208 ? 201.259 178.287 157.479 1.00 68.67 ? 208 MET C SD  1 
ATOM 3147 C CE  . MET C 1 208 ? 202.948 178.554 156.944 1.00 54.38 ? 208 MET C CE  1 
ATOM 3148 N N   . MET C 1 209 ? 195.966 179.669 155.134 1.00 44.54 ? 209 MET C N   1 
ATOM 3149 C CA  . MET C 1 209 ? 194.523 179.420 155.169 1.00 45.03 ? 209 MET C CA  1 
ATOM 3150 C C   . MET C 1 209 ? 194.294 178.024 154.589 1.00 51.23 ? 209 MET C C   1 
ATOM 3151 O O   . MET C 1 209 ? 194.156 177.862 153.374 1.00 56.05 ? 209 MET C O   1 
ATOM 3152 C CB  . MET C 1 209 ? 193.779 180.497 154.386 1.00 52.34 ? 209 MET C CB  1 
ATOM 3153 C CG  . MET C 1 209 ? 192.351 180.751 154.829 1.00 52.52 ? 209 MET C CG  1 
ATOM 3154 S SD  . MET C 1 209 ? 192.249 181.857 156.249 1.00 58.69 ? 209 MET C SD  1 
ATOM 3155 C CE  . MET C 1 209 ? 190.491 182.191 156.296 1.00 43.13 ? 209 MET C CE  1 
ATOM 3156 N N   . GLU C 1 210 ? 194.257 177.021 155.464 1.00 47.20 ? 210 GLU C N   1 
ATOM 3157 C CA  . GLU C 1 210 ? 194.138 175.629 155.047 1.00 50.27 ? 210 GLU C CA  1 
ATOM 3158 C C   . GLU C 1 210 ? 193.026 174.946 155.827 1.00 43.23 ? 210 GLU C C   1 
ATOM 3159 O O   . GLU C 1 210 ? 192.984 175.036 157.057 1.00 42.12 ? 210 GLU C O   1 
ATOM 3160 C CB  . GLU C 1 210 ? 195.458 174.877 155.245 1.00 48.50 ? 210 GLU C CB  1 
ATOM 3161 C CG  . GLU C 1 210 ? 196.484 175.134 154.158 1.00 51.76 ? 210 GLU C CG  1 
ATOM 3162 C CD  . GLU C 1 210 ? 197.369 173.931 153.904 1.00 53.42 ? 210 GLU C CD  1 
ATOM 3163 O OE1 . GLU C 1 210 ? 197.482 173.074 154.806 1.00 55.46 ? 210 GLU C OE1 1 
ATOM 3164 O OE2 . GLU C 1 210 ? 197.947 173.840 152.801 1.00 50.29 ? 210 GLU C OE2 1 
ATOM 3165 N N   . ARG C 1 211 ? 192.132 174.266 155.105 1.00 45.35 ? 211 ARG C N   1 
ATOM 3166 C CA  . ARG C 1 211 ? 191.049 173.486 155.709 1.00 46.47 ? 211 ARG C CA  1 
ATOM 3167 C C   . ARG C 1 211 ? 190.231 174.340 156.675 1.00 46.82 ? 211 ARG C C   1 
ATOM 3168 O O   . ARG C 1 211 ? 189.781 173.878 157.724 1.00 46.12 ? 211 ARG C O   1 
ATOM 3169 C CB  . ARG C 1 211 ? 191.603 172.241 156.405 1.00 47.45 ? 211 ARG C CB  1 
ATOM 3170 C CG  . ARG C 1 211 ? 190.723 171.002 156.309 1.00 45.59 ? 211 ARG C CG  1 
ATOM 3171 C CD  . ARG C 1 211 ? 191.448 169.788 156.873 1.00 45.05 ? 211 ARG C CD  1 
ATOM 3172 N NE  . ARG C 1 211 ? 190.551 168.893 157.592 1.00 48.98 ? 211 ARG C NE  1 
ATOM 3173 C CZ  . ARG C 1 211 ? 190.952 167.871 158.334 1.00 50.76 ? 211 ARG C CZ  1 
ATOM 3174 N NH1 . ARG C 1 211 ? 192.234 167.583 158.480 1.00 49.50 ? 211 ARG C NH1 1 
ATOM 3175 N NH2 . ARG C 1 211 ? 190.042 167.121 158.951 1.00 47.89 ? 211 ARG C NH2 1 
ATOM 3176 N N   . VAL C 1 212 ? 190.025 175.605 156.302 1.00 48.66 ? 212 VAL C N   1 
ATOM 3177 C CA  . VAL C 1 212 ? 189.448 176.585 157.217 1.00 45.24 ? 212 VAL C CA  1 
ATOM 3178 C C   . VAL C 1 212 ? 187.949 176.370 157.388 1.00 46.06 ? 212 VAL C C   1 
ATOM 3179 O O   . VAL C 1 212 ? 187.429 176.442 158.505 1.00 51.41 ? 212 VAL C O   1 
ATOM 3180 C CB  . VAL C 1 212 ? 189.769 178.011 156.738 1.00 45.29 ? 212 VAL C CB  1 
ATOM 3181 C CG1 . VAL C 1 212 ? 188.940 179.028 157.501 1.00 45.67 ? 212 VAL C CG1 1 
ATOM 3182 C CG2 . VAL C 1 212 ? 191.239 178.289 156.934 1.00 47.61 ? 212 VAL C CG2 1 
ATOM 3183 N N   . VAL C 1 213 ? 187.225 176.163 156.290 1.00 40.84 ? 213 VAL C N   1 
ATOM 3184 C CA  . VAL C 1 213 ? 185.817 175.777 156.327 1.00 41.21 ? 213 VAL C CA  1 
ATOM 3185 C C   . VAL C 1 213 ? 185.673 174.545 155.447 1.00 47.58 ? 213 VAL C C   1 
ATOM 3186 O O   . VAL C 1 213 ? 185.893 174.613 154.233 1.00 48.73 ? 213 VAL C O   1 
ATOM 3187 C CB  . VAL C 1 213 ? 184.892 176.913 155.859 1.00 44.20 ? 213 VAL C CB  1 
ATOM 3188 C CG1 . VAL C 1 213 ? 183.437 176.543 156.097 1.00 41.51 ? 213 VAL C CG1 1 
ATOM 3189 C CG2 . VAL C 1 213 ? 185.234 178.215 156.572 1.00 44.98 ? 213 VAL C CG2 1 
ATOM 3190 N N   . GLU C 1 214 ? 185.258 173.428 156.040 1.00 49.20 ? 214 GLU C N   1 
ATOM 3191 C CA  . GLU C 1 214 ? 185.087 172.215 155.248 1.00 43.81 ? 214 GLU C CA  1 
ATOM 3192 C C   . GLU C 1 214 ? 183.673 172.104 154.698 1.00 42.04 ? 214 GLU C C   1 
ATOM 3193 O O   . GLU C 1 214 ? 183.495 171.730 153.536 1.00 48.73 ? 214 GLU C O   1 
ATOM 3194 C CB  . GLU C 1 214 ? 185.437 170.970 156.070 1.00 47.54 ? 214 GLU C CB  1 
ATOM 3195 C CG  . GLU C 1 214 ? 186.924 170.680 156.186 1.00 44.93 ? 214 GLU C CG  1 
ATOM 3196 C CD  . GLU C 1 214 ? 187.203 169.390 156.931 1.00 49.26 ? 214 GLU C CD  1 
ATOM 3197 O OE1 . GLU C 1 214 ? 186.356 168.985 157.757 1.00 50.88 ? 214 GLU C OE1 1 
ATOM 3198 O OE2 . GLU C 1 214 ? 188.268 168.782 156.700 1.00 51.10 ? 214 GLU C OE2 1 
ATOM 3199 N N   . GLN C 1 215 ? 182.665 172.422 155.505 1.00 37.13 ? 215 GLN C N   1 
ATOM 3200 C CA  . GLN C 1 215 ? 181.281 172.414 155.060 1.00 36.66 ? 215 GLN C CA  1 
ATOM 3201 C C   . GLN C 1 215 ? 180.549 173.605 155.657 1.00 42.88 ? 215 GLN C C   1 
ATOM 3202 O O   . GLN C 1 215 ? 180.881 174.072 156.749 1.00 43.51 ? 215 GLN C O   1 
ATOM 3203 C CB  . GLN C 1 215 ? 180.582 171.107 155.458 1.00 40.01 ? 215 GLN C CB  1 
ATOM 3204 C CG  . GLN C 1 215 ? 180.895 169.939 154.543 1.00 38.49 ? 215 GLN C CG  1 
ATOM 3205 C CD  . GLN C 1 215 ? 182.181 169.232 154.920 1.00 43.54 ? 215 GLN C CD  1 
ATOM 3206 O OE1 . GLN C 1 215 ? 182.518 169.113 156.097 1.00 44.42 ? 215 GLN C OE1 1 
ATOM 3207 N NE2 . GLN C 1 215 ? 182.916 168.776 153.916 1.00 37.51 ? 215 GLN C NE2 1 
ATOM 3208 N N   . MET C 1 216 ? 179.545 174.088 154.930 1.00 48.32 ? 216 MET C N   1 
ATOM 3209 C CA  . MET C 1 216 ? 178.739 175.211 155.391 1.00 43.39 ? 216 MET C CA  1 
ATOM 3210 C C   . MET C 1 216 ? 177.415 175.188 154.643 1.00 40.31 ? 216 MET C C   1 
ATOM 3211 O O   . MET C 1 216 ? 177.391 174.990 153.428 1.00 42.89 ? 216 MET C O   1 
ATOM 3212 C CB  . MET C 1 216 ? 179.467 176.545 155.188 1.00 41.54 ? 216 MET C CB  1 
ATOM 3213 C CG  . MET C 1 216 ? 178.837 177.714 155.929 1.00 44.60 ? 216 MET C CG  1 
ATOM 3214 S SD  . MET C 1 216 ? 179.953 179.115 156.135 1.00 53.13 ? 216 MET C SD  1 
ATOM 3215 C CE  . MET C 1 216 ? 180.975 178.967 154.672 1.00 49.74 ? 216 MET C CE  1 
ATOM 3216 N N   . CYS C 1 217 ? 176.322 175.396 155.382 1.00 43.52 ? 217 CYS C N   1 
ATOM 3217 C CA  . CYS C 1 217 ? 174.972 175.441 154.812 1.00 39.89 ? 217 CYS C CA  1 
ATOM 3218 C C   . CYS C 1 217 ? 174.645 174.179 154.018 1.00 39.07 ? 217 CYS C C   1 
ATOM 3219 O O   . CYS C 1 217 ? 174.035 174.238 152.948 1.00 39.65 ? 217 CYS C O   1 
ATOM 3220 C CB  . CYS C 1 217 ? 174.793 176.686 153.943 1.00 39.68 ? 217 CYS C CB  1 
ATOM 3221 S SG  . CYS C 1 217 ? 175.508 178.183 154.645 1.00 56.99 ? 217 CYS C SG  1 
ATOM 3222 N N   . ILE C 1 218 ? 175.045 173.026 154.548 1.00 39.60 ? 218 ILE C N   1 
ATOM 3223 C CA  . ILE C 1 218 ? 174.802 171.743 153.887 1.00 40.89 ? 218 ILE C CA  1 
ATOM 3224 C C   . ILE C 1 218 ? 173.430 171.267 154.357 1.00 37.93 ? 218 ILE C C   1 
ATOM 3225 O O   . ILE C 1 218 ? 173.287 170.637 155.405 1.00 43.77 ? 218 ILE C O   1 
ATOM 3226 C CB  . ILE C 1 218 ? 175.901 170.726 154.181 1.00 38.54 ? 218 ILE C CB  1 
ATOM 3227 C CG1 . ILE C 1 218 ? 177.280 171.336 153.920 1.00 40.26 ? 218 ILE C CG1 1 
ATOM 3228 C CG2 . ILE C 1 218 ? 175.703 169.474 153.344 1.00 33.45 ? 218 ILE C CG2 1 
ATOM 3229 C CD1 . ILE C 1 218 ? 177.441 171.935 152.550 1.00 36.50 ? 218 ILE C CD1 1 
ATOM 3230 N N   . THR C 1 219 ? 172.405 171.579 153.567 1.00 27.02 ? 219 THR C N   1 
ATOM 3231 C CA  . THR C 1 219 ? 171.044 171.119 153.838 1.00 30.50 ? 219 THR C CA  1 
ATOM 3232 C C   . THR C 1 219 ? 170.866 169.784 153.128 1.00 34.48 ? 219 THR C C   1 
ATOM 3233 O O   . THR C 1 219 ? 170.390 169.715 151.994 1.00 35.24 ? 219 THR C O   1 
ATOM 3234 C CB  . THR C 1 219 ? 170.018 172.147 153.379 1.00 33.52 ? 219 THR C CB  1 
ATOM 3235 O OG1 . THR C 1 219 ? 170.371 173.438 153.892 1.00 36.53 ? 219 THR C OG1 1 
ATOM 3236 C CG2 . THR C 1 219 ? 168.631 171.772 153.879 1.00 32.51 ? 219 THR C CG2 1 
ATOM 3237 N N   . GLN C 1 220 ? 171.259 168.710 153.805 1.00 27.57 ? 220 GLN C N   1 
ATOM 3238 C CA  . GLN C 1 220 ? 171.258 167.372 153.231 1.00 24.68 ? 220 GLN C CA  1 
ATOM 3239 C C   . GLN C 1 220 ? 170.248 166.497 153.958 1.00 19.70 ? 220 GLN C C   1 
ATOM 3240 O O   . GLN C 1 220 ? 170.292 166.381 155.187 1.00 31.43 ? 220 GLN C O   1 
ATOM 3241 C CB  . GLN C 1 220 ? 172.652 166.746 153.310 1.00 26.51 ? 220 GLN C CB  1 
ATOM 3242 C CG  . GLN C 1 220 ? 172.879 165.607 152.334 1.00 31.04 ? 220 GLN C CG  1 
ATOM 3243 C CD  . GLN C 1 220 ? 174.349 165.316 152.114 1.00 32.04 ? 220 GLN C CD  1 
ATOM 3244 O OE1 . GLN C 1 220 ? 175.056 164.906 153.034 1.00 34.98 ? 220 GLN C OE1 1 
ATOM 3245 N NE2 . GLN C 1 220 ? 174.817 165.524 150.889 1.00 27.30 ? 220 GLN C NE2 1 
ATOM 3246 N N   . TYR C 1 221 ? 169.344 165.884 153.200 1.00 18.91 ? 221 TYR C N   1 
ATOM 3247 C CA  . TYR C 1 221 ? 168.381 164.931 153.735 1.00 26.03 ? 221 TYR C CA  1 
ATOM 3248 C C   . TYR C 1 221 ? 168.817 163.535 153.312 1.00 28.67 ? 221 TYR C C   1 
ATOM 3249 O O   . TYR C 1 221 ? 168.966 163.264 152.115 1.00 27.26 ? 221 TYR C O   1 
ATOM 3250 C CB  . TYR C 1 221 ? 166.963 165.229 153.244 1.00 31.08 ? 221 TYR C CB  1 
ATOM 3251 C CG  . TYR C 1 221 ? 166.473 166.628 153.549 1.00 34.35 ? 221 TYR C CG  1 
ATOM 3252 C CD1 . TYR C 1 221 ? 167.054 167.391 154.554 1.00 32.87 ? 221 TYR C CD1 1 
ATOM 3253 C CD2 . TYR C 1 221 ? 165.421 167.184 152.833 1.00 32.90 ? 221 TYR C CD2 1 
ATOM 3254 C CE1 . TYR C 1 221 ? 166.610 168.669 154.830 1.00 32.11 ? 221 TYR C CE1 1 
ATOM 3255 C CE2 . TYR C 1 221 ? 164.968 168.461 153.104 1.00 31.97 ? 221 TYR C CE2 1 
ATOM 3256 C CZ  . TYR C 1 221 ? 165.565 169.198 154.104 1.00 34.85 ? 221 TYR C CZ  1 
ATOM 3257 O OH  . TYR C 1 221 ? 165.119 170.470 154.377 1.00 40.38 ? 221 TYR C OH  1 
ATOM 3258 N N   . GLN C 1 222 ? 169.023 162.658 154.289 1.00 28.93 ? 222 GLN C N   1 
ATOM 3259 C CA  . GLN C 1 222 ? 169.566 161.327 154.053 1.00 19.01 ? 222 GLN C CA  1 
ATOM 3260 C C   . GLN C 1 222 ? 168.564 160.274 154.500 1.00 20.66 ? 222 GLN C C   1 
ATOM 3261 O O   . GLN C 1 222 ? 168.000 160.372 155.594 1.00 30.48 ? 222 GLN C O   1 
ATOM 3262 C CB  . GLN C 1 222 ? 170.892 161.140 154.793 1.00 23.57 ? 222 GLN C CB  1 
ATOM 3263 C CG  . GLN C 1 222 ? 172.028 162.002 154.274 1.00 31.19 ? 222 GLN C CG  1 
ATOM 3264 C CD  . GLN C 1 222 ? 173.334 161.730 154.994 1.00 31.12 ? 222 GLN C CD  1 
ATOM 3265 O OE1 . GLN C 1 222 ? 173.374 160.974 155.965 1.00 25.97 ? 222 GLN C OE1 1 
ATOM 3266 N NE2 . GLN C 1 222 ? 174.409 162.347 154.523 1.00 30.01 ? 222 GLN C NE2 1 
ATOM 3267 N N   . ARG C 1 223 ? 168.347 159.271 153.651 1.00 26.00 ? 223 ARG C N   1 
ATOM 3268 C CA  . ARG C 1 223 ? 167.494 158.129 153.981 1.00 34.43 ? 223 ARG C CA  1 
ATOM 3269 C C   . ARG C 1 223 ? 168.182 156.880 153.438 1.00 30.07 ? 223 ARG C C   1 
ATOM 3270 O O   . ARG C 1 223 ? 168.164 156.637 152.228 1.00 23.53 ? 223 ARG C O   1 
ATOM 3271 C CB  . ARG C 1 223 ? 166.092 158.288 153.408 1.00 31.74 ? 223 ARG C CB  1 
ATOM 3272 C CG  . ARG C 1 223 ? 165.228 157.046 153.551 1.00 30.02 ? 223 ARG C CG  1 
ATOM 3273 C CD  . ARG C 1 223 ? 163.865 157.244 152.913 1.00 34.03 ? 223 ARG C CD  1 
ATOM 3274 N NE  . ARG C 1 223 ? 162.947 157.954 153.794 1.00 41.45 ? 223 ARG C NE  1 
ATOM 3275 C CZ  . ARG C 1 223 ? 162.178 157.367 154.701 1.00 40.46 ? 223 ARG C CZ  1 
ATOM 3276 N NH1 . ARG C 1 223 ? 162.191 156.057 154.876 1.00 32.84 ? 223 ARG C NH1 1 
ATOM 3277 N NH2 . ARG C 1 223 ? 161.376 158.117 155.453 1.00 38.48 ? 223 ARG C NH2 1 
ATOM 3278 N N   . GLU C 1 224 ? 168.784 156.099 154.338 1.00 37.17 ? 224 GLU C N   1 
ATOM 3279 C CA  . GLU C 1 224 ? 169.529 154.893 153.970 1.00 35.63 ? 224 GLU C CA  1 
ATOM 3280 C C   . GLU C 1 224 ? 170.618 155.209 152.948 1.00 31.88 ? 224 GLU C C   1 
ATOM 3281 O O   . GLU C 1 224 ? 170.890 154.423 152.039 1.00 30.40 ? 224 GLU C O   1 
ATOM 3282 C CB  . GLU C 1 224 ? 168.593 153.800 153.448 1.00 36.99 ? 224 GLU C CB  1 
ATOM 3283 C CG  . GLU C 1 224 ? 167.357 153.584 154.303 1.00 38.56 ? 224 GLU C CG  1 
ATOM 3284 C CD  . GLU C 1 224 ? 166.232 152.915 153.538 1.00 39.04 ? 224 GLU C CD  1 
ATOM 3285 O OE1 . GLU C 1 224 ? 166.523 152.057 152.679 1.00 44.99 ? 224 GLU C OE1 1 
ATOM 3286 O OE2 . GLU C 1 224 ? 165.056 153.249 153.795 1.00 37.17 ? 224 GLU C OE2 1 
ATOM 3287 N N   . SER C 1 225 ? 171.252 156.366 153.106 1.00 30.11 ? 225 SER C N   1 
ATOM 3288 C CA  . SER C 1 225 ? 172.229 156.869 152.156 1.00 28.70 ? 225 SER C CA  1 
ATOM 3289 C C   . SER C 1 225 ? 173.560 157.122 152.853 1.00 29.20 ? 225 SER C C   1 
ATOM 3290 O O   . SER C 1 225 ? 173.679 157.024 154.077 1.00 39.53 ? 225 SER C O   1 
ATOM 3291 C CB  . SER C 1 225 ? 171.727 158.153 151.484 1.00 30.27 ? 225 SER C CB  1 
ATOM 3292 O OG  . SER C 1 225 ? 170.529 157.916 150.766 1.00 37.64 ? 225 SER C OG  1 
ATOM 3293 N N   . GLN C 1 226 ? 174.572 157.446 152.052 1.00 33.40 ? 226 GLN C N   1 
ATOM 3294 C CA  . GLN C 1 226 ? 175.912 157.696 152.562 1.00 32.84 ? 226 GLN C CA  1 
ATOM 3295 C C   . GLN C 1 226 ? 176.486 158.940 151.903 1.00 32.49 ? 226 GLN C C   1 
ATOM 3296 O O   . GLN C 1 226 ? 176.310 159.153 150.700 1.00 32.50 ? 226 GLN C O   1 
ATOM 3297 C CB  . GLN C 1 226 ? 176.838 156.498 152.317 1.00 20.31 ? 226 GLN C CB  1 
ATOM 3298 C CG  . GLN C 1 226 ? 176.547 155.294 153.197 1.00 24.05 ? 226 GLN C CG  1 
ATOM 3299 C CD  . GLN C 1 226 ? 175.422 154.435 152.656 1.00 30.51 ? 226 GLN C CD  1 
ATOM 3300 O OE1 . GLN C 1 226 ? 175.274 154.277 151.444 1.00 31.21 ? 226 GLN C OE1 1 
ATOM 3301 N NE2 . GLN C 1 226 ? 174.618 153.878 153.554 1.00 34.29 ? 226 GLN C NE2 1 
ATOM 3302 N N   . ALA C 1 227 ? 177.170 159.759 152.699 1.00 24.60 ? 227 ALA C N   1 
ATOM 3303 C CA  . ALA C 1 227 ? 177.859 160.944 152.207 1.00 21.13 ? 227 ALA C CA  1 
ATOM 3304 C C   . ALA C 1 227 ? 179.276 160.950 152.756 1.00 27.62 ? 227 ALA C C   1 
ATOM 3305 O O   . ALA C 1 227 ? 179.475 160.801 153.966 1.00 26.65 ? 227 ALA C O   1 
ATOM 3306 C CB  . ALA C 1 227 ? 177.125 162.226 152.610 1.00 25.28 ? 227 ALA C CB  1 
ATOM 3307 N N   . TYR C 1 228 ? 180.254 161.121 151.871 1.00 37.96 ? 228 TYR C N   1 
ATOM 3308 C CA  . TYR C 1 228 ? 181.664 161.109 152.238 1.00 32.61 ? 228 TYR C CA  1 
ATOM 3309 C C   . TYR C 1 228 ? 182.283 162.444 151.853 1.00 28.12 ? 228 TYR C C   1 
ATOM 3310 O O   . TYR C 1 228 ? 182.233 162.840 150.683 1.00 41.58 ? 228 TYR C O   1 
ATOM 3311 C CB  . TYR C 1 228 ? 182.399 159.954 151.555 1.00 24.71 ? 228 TYR C CB  1 
ATOM 3312 C CG  . TYR C 1 228 ? 181.930 158.587 151.998 1.00 26.42 ? 228 TYR C CG  1 
ATOM 3313 C CD1 . TYR C 1 228 ? 180.797 158.007 151.444 1.00 24.15 ? 228 TYR C CD1 1 
ATOM 3314 C CD2 . TYR C 1 228 ? 182.620 157.878 152.971 1.00 29.54 ? 228 TYR C CD2 1 
ATOM 3315 C CE1 . TYR C 1 228 ? 180.365 156.758 151.846 1.00 30.89 ? 228 TYR C CE1 1 
ATOM 3316 C CE2 . TYR C 1 228 ? 182.196 156.628 153.379 1.00 32.18 ? 228 TYR C CE2 1 
ATOM 3317 C CZ  . TYR C 1 228 ? 181.067 156.074 152.814 1.00 30.31 ? 228 TYR C CZ  1 
ATOM 3318 O OH  . TYR C 1 228 ? 180.639 154.829 153.216 1.00 33.57 ? 228 TYR C OH  1 
ATOM 3319 N N   . TYR C 1 229 ? 182.867 163.128 152.830 1.00 21.12 ? 229 TYR C N   1 
ATOM 3320 C CA  . TYR C 1 229 ? 183.474 164.431 152.596 1.00 17.80 ? 229 TYR C CA  1 
ATOM 3321 C C   . TYR C 1 229 ? 184.986 164.374 152.783 1.00 24.83 ? 229 TYR C C   1 
ATOM 3322 O O   . TYR C 1 229 ? 185.474 163.988 153.845 1.00 35.68 ? 229 TYR C O   1 
ATOM 3323 C CB  . TYR C 1 229 ? 182.866 165.480 153.530 1.00 29.15 ? 229 TYR C CB  1 
ATOM 3324 C CG  . TYR C 1 229 ? 181.371 165.649 153.374 1.00 32.70 ? 229 TYR C CG  1 
ATOM 3325 C CD1 . TYR C 1 229 ? 180.848 166.571 152.476 1.00 25.81 ? 229 TYR C CD1 1 
ATOM 3326 C CD2 . TYR C 1 229 ? 180.483 164.892 154.126 1.00 26.63 ? 229 TYR C CD2 1 
ATOM 3327 C CE1 . TYR C 1 229 ? 179.484 166.730 152.329 1.00 23.56 ? 229 TYR C CE1 1 
ATOM 3328 C CE2 . TYR C 1 229 ? 179.118 165.043 153.986 1.00 23.50 ? 229 TYR C CE2 1 
ATOM 3329 C CZ  . TYR C 1 229 ? 178.623 165.964 153.087 1.00 31.98 ? 229 TYR C CZ  1 
ATOM 3330 O OH  . TYR C 1 229 ? 177.264 166.119 152.945 1.00 37.18 ? 229 TYR C OH  1 
ATOM 3331 N N   . GLY D 1 92  ? 108.574 166.655 162.606 1.00 20.68 ? 92  GLY D N   1 
ATOM 3332 C CA  . GLY D 1 92  ? 109.416 165.524 162.949 1.00 21.41 ? 92  GLY D CA  1 
ATOM 3333 C C   . GLY D 1 92  ? 110.593 165.350 162.010 1.00 23.11 ? 92  GLY D C   1 
ATOM 3334 O O   . GLY D 1 92  ? 110.807 164.270 161.461 1.00 20.48 ? 92  GLY D O   1 
ATOM 3335 N N   . TRP D 1 93  ? 111.360 166.421 161.825 1.00 18.12 ? 93  TRP D N   1 
ATOM 3336 C CA  . TRP D 1 93  ? 112.514 166.400 160.945 1.00 8.04  ? 93  TRP D CA  1 
ATOM 3337 C C   . TRP D 1 93  ? 113.745 165.903 161.700 1.00 13.07 ? 93  TRP D C   1 
ATOM 3338 O O   . TRP D 1 93  ? 113.689 165.565 162.884 1.00 20.48 ? 93  TRP D O   1 
ATOM 3339 C CB  . TRP D 1 93  ? 112.752 167.786 160.349 1.00 14.88 ? 93  TRP D CB  1 
ATOM 3340 C CG  . TRP D 1 93  ? 112.879 168.868 161.378 1.00 13.87 ? 93  TRP D CG  1 
ATOM 3341 C CD1 . TRP D 1 93  ? 111.871 169.626 161.897 1.00 14.01 ? 93  TRP D CD1 1 
ATOM 3342 C CD2 . TRP D 1 93  ? 114.084 169.312 162.014 1.00 18.34 ? 93  TRP D CD2 1 
ATOM 3343 N NE1 . TRP D 1 93  ? 112.372 170.515 162.816 1.00 12.85 ? 93  TRP D NE1 1 
ATOM 3344 C CE2 . TRP D 1 93  ? 113.729 170.343 162.905 1.00 14.76 ? 93  TRP D CE2 1 
ATOM 3345 C CE3 . TRP D 1 93  ? 115.427 168.939 161.916 1.00 13.41 ? 93  TRP D CE3 1 
ATOM 3346 C CZ2 . TRP D 1 93  ? 114.667 171.001 163.696 1.00 16.24 ? 93  TRP D CZ2 1 
ATOM 3347 C CZ3 . TRP D 1 93  ? 116.357 169.595 162.699 1.00 16.46 ? 93  TRP D CZ3 1 
ATOM 3348 C CH2 . TRP D 1 93  ? 115.973 170.615 163.577 1.00 14.58 ? 93  TRP D CH2 1 
ATOM 3349 N N   . GLY D 1 94  ? 114.877 165.858 161.003 1.00 12.32 ? 94  GLY D N   1 
ATOM 3350 C CA  . GLY D 1 94  ? 116.110 165.402 161.611 1.00 20.82 ? 94  GLY D CA  1 
ATOM 3351 C C   . GLY D 1 94  ? 117.354 165.865 160.884 1.00 1.63  ? 94  GLY D C   1 
ATOM 3352 O O   . GLY D 1 94  ? 117.444 165.759 159.658 1.00 6.23  ? 94  GLY D O   1 
ATOM 3353 N N   . GLN D 1 95  ? 118.325 166.378 161.631 1.00 3.89  ? 95  GLN D N   1 
ATOM 3354 C CA  . GLN D 1 95  ? 119.603 166.809 161.083 1.00 7.12  ? 95  GLN D CA  1 
ATOM 3355 C C   . GLN D 1 95  ? 120.694 165.866 161.567 1.00 14.08 ? 95  GLN D C   1 
ATOM 3356 O O   . GLN D 1 95  ? 120.833 165.639 162.774 1.00 11.67 ? 95  GLN D O   1 
ATOM 3357 C CB  . GLN D 1 95  ? 119.920 168.249 161.492 1.00 20.06 ? 95  GLN D CB  1 
ATOM 3358 C CG  . GLN D 1 95  ? 119.282 169.303 160.600 1.00 12.05 ? 95  GLN D CG  1 
ATOM 3359 C CD  . GLN D 1 95  ? 119.555 170.714 161.081 1.00 13.50 ? 95  GLN D CD  1 
ATOM 3360 O OE1 . GLN D 1 95  ? 119.296 171.049 162.237 1.00 21.18 ? 95  GLN D OE1 1 
ATOM 3361 N NE2 . GLN D 1 95  ? 120.079 171.551 160.193 1.00 9.13  ? 95  GLN D NE2 1 
ATOM 3362 N N   . GLY D 1 96  ? 121.460 165.318 160.628 1.00 19.23 ? 96  GLY D N   1 
ATOM 3363 C CA  . GLY D 1 96  ? 122.496 164.372 160.987 1.00 15.72 ? 96  GLY D CA  1 
ATOM 3364 C C   . GLY D 1 96  ? 123.612 165.018 161.786 1.00 11.39 ? 96  GLY D C   1 
ATOM 3365 O O   . GLY D 1 96  ? 123.909 166.205 161.646 1.00 15.84 ? 96  GLY D O   1 
ATOM 3366 N N   . GLY D 1 97  ? 124.234 164.214 162.644 1.00 26.07 ? 97  GLY D N   1 
ATOM 3367 C CA  . GLY D 1 97  ? 125.325 164.713 163.457 1.00 21.87 ? 97  GLY D CA  1 
ATOM 3368 C C   . GLY D 1 97  ? 126.521 165.119 162.618 1.00 19.44 ? 97  GLY D C   1 
ATOM 3369 O O   . GLY D 1 97  ? 126.834 164.511 161.594 1.00 24.60 ? 97  GLY D O   1 
ATOM 3370 N N   . THR D 1 98  ? 127.202 166.166 163.067 1.00 16.16 ? 98  THR D N   1 
ATOM 3371 C CA  . THR D 1 98  ? 128.342 166.723 162.354 1.00 20.45 ? 98  THR D CA  1 
ATOM 3372 C C   . THR D 1 98  ? 129.632 166.245 163.007 1.00 28.17 ? 98  THR D C   1 
ATOM 3373 O O   . THR D 1 98  ? 129.874 166.517 164.188 1.00 24.95 ? 98  THR D O   1 
ATOM 3374 C CB  . THR D 1 98  ? 128.289 168.250 162.339 1.00 27.73 ? 98  THR D CB  1 
ATOM 3375 O OG1 . THR D 1 98  ? 127.127 168.685 161.621 1.00 34.87 ? 98  THR D OG1 1 
ATOM 3376 C CG2 . THR D 1 98  ? 129.530 168.811 161.668 1.00 25.45 ? 98  THR D CG2 1 
ATOM 3377 N N   . HIS D 1 99  ? 130.452 165.533 162.239 1.00 29.53 ? 99  HIS D N   1 
ATOM 3378 C CA  . HIS D 1 99  ? 131.790 165.121 162.658 1.00 21.77 ? 99  HIS D CA  1 
ATOM 3379 C C   . HIS D 1 99  ? 132.770 165.796 161.708 1.00 18.56 ? 99  HIS D C   1 
ATOM 3380 O O   . HIS D 1 99  ? 133.215 165.204 160.723 1.00 27.14 ? 99  HIS D O   1 
ATOM 3381 C CB  . HIS D 1 99  ? 131.936 163.593 162.645 1.00 23.79 ? 99  HIS D CB  1 
ATOM 3382 C CG  . HIS D 1 99  ? 130.824 162.874 163.344 1.00 31.37 ? 99  HIS D CG  1 
ATOM 3383 N ND1 . HIS D 1 99  ? 129.554 162.774 162.817 1.00 26.06 ? 99  HIS D ND1 1 
ATOM 3384 C CD2 . HIS D 1 99  ? 130.793 162.216 164.526 1.00 33.68 ? 99  HIS D CD2 1 
ATOM 3385 C CE1 . HIS D 1 99  ? 128.788 162.088 163.646 1.00 25.46 ? 99  HIS D CE1 1 
ATOM 3386 N NE2 . HIS D 1 99  ? 129.515 161.737 164.691 1.00 32.69 ? 99  HIS D NE2 1 
ATOM 3387 N N   . SER D 1 100 ? 133.115 167.043 162.017 1.00 24.22 ? 100 SER D N   1 
ATOM 3388 C CA  . SER D 1 100 ? 133.900 167.884 161.127 1.00 20.38 ? 100 SER D CA  1 
ATOM 3389 C C   . SER D 1 100 ? 135.129 168.401 161.854 1.00 22.99 ? 100 SER D C   1 
ATOM 3390 O O   . SER D 1 100 ? 135.065 168.740 163.038 1.00 27.23 ? 100 SER D O   1 
ATOM 3391 C CB  . SER D 1 100 ? 133.067 169.059 160.604 1.00 26.48 ? 100 SER D CB  1 
ATOM 3392 O OG  . SER D 1 100 ? 132.096 168.619 159.671 1.00 26.03 ? 100 SER D OG  1 
ATOM 3393 N N   . GLN D 1 101 ? 136.248 168.465 161.140 1.00 21.79 ? 101 GLN D N   1 
ATOM 3394 C CA  . GLN D 1 101 ? 137.507 168.917 161.714 1.00 20.71 ? 101 GLN D CA  1 
ATOM 3395 C C   . GLN D 1 101 ? 138.083 170.040 160.867 1.00 10.68 ? 101 GLN D C   1 
ATOM 3396 O O   . GLN D 1 101 ? 138.263 169.878 159.658 1.00 30.42 ? 101 GLN D O   1 
ATOM 3397 C CB  . GLN D 1 101 ? 138.515 167.766 161.811 1.00 12.44 ? 101 GLN D CB  1 
ATOM 3398 C CG  . GLN D 1 101 ? 138.142 166.699 162.827 1.00 10.43 ? 101 GLN D CG  1 
ATOM 3399 C CD  . GLN D 1 101 ? 137.188 165.665 162.263 1.00 15.80 ? 101 GLN D CD  1 
ATOM 3400 O OE1 . GLN D 1 101 ? 137.239 165.339 161.077 1.00 20.91 ? 101 GLN D OE1 1 
ATOM 3401 N NE2 . GLN D 1 101 ? 136.311 165.143 163.111 1.00 23.88 ? 101 GLN D NE2 1 
ATOM 3402 N N   . TRP D 1 102 ? 138.376 171.175 161.504 1.00 6.30  ? 102 TRP D N   1 
ATOM 3403 C CA  . TRP D 1 102 ? 139.036 172.260 160.785 1.00 1.57  ? 102 TRP D CA  1 
ATOM 3404 C C   . TRP D 1 102 ? 140.427 171.856 160.319 1.00 18.29 ? 102 TRP D C   1 
ATOM 3405 O O   . TRP D 1 102 ? 140.929 172.387 159.321 1.00 18.74 ? 102 TRP D O   1 
ATOM 3406 C CB  . TRP D 1 102 ? 139.109 173.511 161.661 1.00 12.63 ? 102 TRP D CB  1 
ATOM 3407 C CG  . TRP D 1 102 ? 139.606 174.718 160.927 1.00 14.90 ? 102 TRP D CG  1 
ATOM 3408 C CD1 . TRP D 1 102 ? 140.826 175.312 161.057 1.00 13.41 ? 102 TRP D CD1 1 
ATOM 3409 C CD2 . TRP D 1 102 ? 138.896 175.473 159.938 1.00 11.77 ? 102 TRP D CD2 1 
ATOM 3410 N NE1 . TRP D 1 102 ? 140.918 176.393 160.215 1.00 9.17  ? 102 TRP D NE1 1 
ATOM 3411 C CE2 . TRP D 1 102 ? 139.746 176.513 159.517 1.00 4.61  ? 102 TRP D CE2 1 
ATOM 3412 C CE3 . TRP D 1 102 ? 137.621 175.372 159.372 1.00 14.49 ? 102 TRP D CE3 1 
ATOM 3413 C CZ2 . TRP D 1 102 ? 139.366 177.445 158.554 1.00 8.88  ? 102 TRP D CZ2 1 
ATOM 3414 C CZ3 . TRP D 1 102 ? 137.246 176.298 158.416 1.00 9.74  ? 102 TRP D CZ3 1 
ATOM 3415 C CH2 . TRP D 1 102 ? 138.114 177.320 158.018 1.00 9.87  ? 102 TRP D CH2 1 
ATOM 3416 N N   . ASN D 1 103 ? 141.061 170.921 161.022 1.00 29.15 ? 103 ASN D N   1 
ATOM 3417 C CA  . ASN D 1 103 ? 142.370 170.408 160.629 1.00 19.27 ? 103 ASN D CA  1 
ATOM 3418 C C   . ASN D 1 103 ? 142.501 169.004 161.202 1.00 23.02 ? 103 ASN D C   1 
ATOM 3419 O O   . ASN D 1 103 ? 142.544 168.835 162.424 1.00 20.73 ? 103 ASN D O   1 
ATOM 3420 C CB  . ASN D 1 103 ? 143.491 171.313 161.129 1.00 10.46 ? 103 ASN D CB  1 
ATOM 3421 C CG  . ASN D 1 103 ? 144.841 170.942 160.550 1.00 23.51 ? 103 ASN D CG  1 
ATOM 3422 O OD1 . ASN D 1 103 ? 144.935 170.468 159.419 1.00 13.51 ? 103 ASN D OD1 1 
ATOM 3423 N ND2 . ASN D 1 103 ? 145.897 171.159 161.326 1.00 25.90 ? 103 ASN D ND2 1 
ATOM 3424 N N   . LYS D 1 104 ? 142.562 168.003 160.325 1.00 14.47 ? 104 LYS D N   1 
ATOM 3425 C CA  . LYS D 1 104 ? 142.657 166.599 160.726 1.00 13.11 ? 104 LYS D CA  1 
ATOM 3426 C C   . LYS D 1 104 ? 143.833 165.952 160.008 1.00 21.71 ? 104 LYS D C   1 
ATOM 3427 O O   . LYS D 1 104 ? 143.650 165.198 159.042 1.00 26.40 ? 104 LYS D O   1 
ATOM 3428 C CB  . LYS D 1 104 ? 141.355 165.851 160.432 1.00 11.00 ? 104 LYS D CB  1 
ATOM 3429 C CG  . LYS D 1 104 ? 141.267 164.482 161.084 1.00 14.11 ? 104 LYS D CG  1 
ATOM 3430 C CD  . LYS D 1 104 ? 140.069 163.702 160.572 1.00 14.28 ? 104 LYS D CD  1 
ATOM 3431 C CE  . LYS D 1 104 ? 140.251 162.208 160.786 1.00 20.12 ? 104 LYS D CE  1 
ATOM 3432 N NZ  . LYS D 1 104 ? 140.313 161.856 162.231 1.00 22.75 ? 104 LYS D NZ  1 
ATOM 3433 N N   . PRO D 1 105 ? 145.061 166.230 160.449 1.00 27.36 ? 105 PRO D N   1 
ATOM 3434 C CA  . PRO D 1 105 ? 146.222 165.551 159.862 1.00 24.88 ? 105 PRO D CA  1 
ATOM 3435 C C   . PRO D 1 105 ? 146.536 164.244 160.574 1.00 27.76 ? 105 PRO D C   1 
ATOM 3436 O O   . PRO D 1 105 ? 146.676 164.217 161.800 1.00 24.01 ? 105 PRO D O   1 
ATOM 3437 C CB  . PRO D 1 105 ? 147.352 166.574 160.032 1.00 20.61 ? 105 PRO D CB  1 
ATOM 3438 C CG  . PRO D 1 105 ? 146.892 167.499 161.144 1.00 27.07 ? 105 PRO D CG  1 
ATOM 3439 C CD  . PRO D 1 105 ? 145.458 167.194 161.487 1.00 26.96 ? 105 PRO D CD  1 
ATOM 3440 N N   . SER D 1 106 ? 146.652 163.158 159.817 1.00 27.43 ? 106 SER D N   1 
ATOM 3441 C CA  . SER D 1 106 ? 146.910 161.839 160.376 1.00 26.39 ? 106 SER D CA  1 
ATOM 3442 C C   . SER D 1 106 ? 148.379 161.484 160.199 1.00 37.67 ? 106 SER D C   1 
ATOM 3443 O O   . SER D 1 106 ? 148.897 161.508 159.079 1.00 36.63 ? 106 SER D O   1 
ATOM 3444 C CB  . SER D 1 106 ? 146.026 160.784 159.710 1.00 30.29 ? 106 SER D CB  1 
ATOM 3445 O OG  . SER D 1 106 ? 146.102 159.547 160.399 1.00 39.13 ? 106 SER D OG  1 
ATOM 3446 N N   . LYS D 1 107 ? 149.039 161.152 161.306 1.00 36.62 ? 107 LYS D N   1 
ATOM 3447 C CA  . LYS D 1 107 ? 150.447 160.770 161.321 1.00 32.08 ? 107 LYS D CA  1 
ATOM 3448 C C   . LYS D 1 107 ? 151.352 161.748 160.565 1.00 32.37 ? 107 LYS D C   1 
ATOM 3449 O O   . LYS D 1 107 ? 152.019 161.362 159.598 1.00 34.11 ? 107 LYS D O   1 
ATOM 3450 C CB  . LYS D 1 107 ? 150.618 159.357 160.780 1.00 30.25 ? 107 LYS D CB  1 
ATOM 3451 C CG  . LYS D 1 107 ? 149.853 158.296 161.552 1.00 33.37 ? 107 LYS D CG  1 
ATOM 3452 C CD  . LYS D 1 107 ? 149.711 157.022 160.736 1.00 33.55 ? 107 LYS D CD  1 
ATOM 3453 C CE  . LYS D 1 107 ? 148.808 156.017 161.432 1.00 31.41 ? 107 LYS D CE  1 
ATOM 3454 N NZ  . LYS D 1 107 ? 148.663 154.765 160.639 1.00 34.53 ? 107 LYS D NZ  1 
ATOM 3455 N N   . PRO D 1 108 ? 151.400 163.022 160.976 1.00 30.95 ? 108 PRO D N   1 
ATOM 3456 C CA  . PRO D 1 108 ? 152.329 163.967 160.342 1.00 28.77 ? 108 PRO D CA  1 
ATOM 3457 C C   . PRO D 1 108 ? 153.740 163.811 160.887 1.00 36.78 ? 108 PRO D C   1 
ATOM 3458 O O   . PRO D 1 108 ? 154.044 164.233 162.008 1.00 43.26 ? 108 PRO D O   1 
ATOM 3459 C CB  . PRO D 1 108 ? 151.719 165.332 160.689 1.00 27.38 ? 108 PRO D CB  1 
ATOM 3460 C CG  . PRO D 1 108 ? 151.065 165.116 161.999 1.00 28.40 ? 108 PRO D CG  1 
ATOM 3461 C CD  . PRO D 1 108 ? 150.633 163.663 162.060 1.00 31.51 ? 108 PRO D CD  1 
ATOM 3462 N N   . LYS D 1 109 ? 154.610 163.202 160.088 1.00 33.61 ? 109 LYS D N   1 
ATOM 3463 C CA  . LYS D 1 109 ? 156.017 163.030 160.432 1.00 28.35 ? 109 LYS D CA  1 
ATOM 3464 C C   . LYS D 1 109 ? 156.799 164.133 159.731 1.00 33.90 ? 109 LYS D C   1 
ATOM 3465 O O   . LYS D 1 109 ? 156.922 164.130 158.502 1.00 34.26 ? 109 LYS D O   1 
ATOM 3466 C CB  . LYS D 1 109 ? 156.515 161.646 160.023 1.00 23.60 ? 109 LYS D CB  1 
ATOM 3467 C CG  . LYS D 1 109 ? 155.948 160.515 160.865 1.00 31.99 ? 109 LYS D CG  1 
ATOM 3468 C CD  . LYS D 1 109 ? 156.413 159.159 160.361 1.00 35.40 ? 109 LYS D CD  1 
ATOM 3469 C CE  . LYS D 1 109 ? 155.833 158.031 161.200 1.00 33.48 ? 109 LYS D CE  1 
ATOM 3470 N NZ  . LYS D 1 109 ? 156.274 156.695 160.716 1.00 38.08 ? 109 LYS D NZ  1 
ATOM 3471 N N   . THR D 1 110 ? 157.329 165.072 160.509 1.00 29.95 ? 110 THR D N   1 
ATOM 3472 C CA  . THR D 1 110 ? 157.928 166.274 159.953 1.00 29.13 ? 110 THR D CA  1 
ATOM 3473 C C   . THR D 1 110 ? 159.255 166.561 160.632 1.00 28.75 ? 110 THR D C   1 
ATOM 3474 O O   . THR D 1 110 ? 159.389 166.400 161.848 1.00 36.30 ? 110 THR D O   1 
ATOM 3475 C CB  . THR D 1 110 ? 156.994 167.480 160.111 1.00 31.82 ? 110 THR D CB  1 
ATOM 3476 O OG1 . THR D 1 110 ? 155.668 167.117 159.706 1.00 34.95 ? 110 THR D OG1 1 
ATOM 3477 C CG2 . THR D 1 110 ? 157.475 168.638 159.259 1.00 28.18 ? 110 THR D CG2 1 
ATOM 3478 N N   . ASN D 1 111 ? 160.235 166.985 159.838 1.00 32.50 ? 111 ASN D N   1 
ATOM 3479 C CA  . ASN D 1 111 ? 161.524 167.442 160.337 1.00 35.76 ? 111 ASN D CA  1 
ATOM 3480 C C   . ASN D 1 111 ? 161.780 168.840 159.797 1.00 29.82 ? 111 ASN D C   1 
ATOM 3481 O O   . ASN D 1 111 ? 161.775 169.048 158.579 1.00 29.82 ? 111 ASN D O   1 
ATOM 3482 C CB  . ASN D 1 111 ? 162.647 166.486 159.929 1.00 31.62 ? 111 ASN D CB  1 
ATOM 3483 C CG  . ASN D 1 111 ? 162.538 165.137 160.611 1.00 27.28 ? 111 ASN D CG  1 
ATOM 3484 O OD1 . ASN D 1 111 ? 162.933 164.980 161.766 1.00 29.74 ? 111 ASN D OD1 1 
ATOM 3485 N ND2 . ASN D 1 111 ? 162.000 164.155 159.898 1.00 31.69 ? 111 ASN D ND2 1 
ATOM 3486 N N   . MET D 1 112 ? 161.997 169.793 160.700 1.00 28.87 ? 112 MET D N   1 
ATOM 3487 C CA  . MET D 1 112 ? 162.240 171.178 160.325 1.00 20.10 ? 112 MET D CA  1 
ATOM 3488 C C   . MET D 1 112 ? 163.166 171.798 161.362 1.00 25.20 ? 112 MET D C   1 
ATOM 3489 O O   . MET D 1 112 ? 163.589 171.141 162.316 1.00 30.65 ? 112 MET D O   1 
ATOM 3490 C CB  . MET D 1 112 ? 160.926 171.953 160.199 1.00 22.06 ? 112 MET D CB  1 
ATOM 3491 C CG  . MET D 1 112 ? 160.017 171.826 161.404 1.00 25.37 ? 112 MET D CG  1 
ATOM 3492 S SD  . MET D 1 112 ? 158.345 172.393 161.054 1.00 36.99 ? 112 MET D SD  1 
ATOM 3493 C CE  . MET D 1 112 ? 157.483 171.802 162.504 1.00 25.12 ? 112 MET D CE  1 
ATOM 3494 N N   . LYS D 1 113 ? 163.499 173.072 161.159 1.00 26.64 ? 113 LYS D N   1 
ATOM 3495 C CA  . LYS D 1 113 ? 164.367 173.785 162.090 1.00 29.89 ? 113 LYS D CA  1 
ATOM 3496 C C   . LYS D 1 113 ? 163.655 174.949 162.767 1.00 31.54 ? 113 LYS D C   1 
ATOM 3497 O O   . LYS D 1 113 ? 163.599 174.994 163.999 1.00 37.97 ? 113 LYS D O   1 
ATOM 3498 C CB  . LYS D 1 113 ? 165.631 174.268 161.366 1.00 28.96 ? 113 LYS D CB  1 
ATOM 3499 C CG  . LYS D 1 113 ? 166.737 174.733 162.297 1.00 33.46 ? 113 LYS D CG  1 
ATOM 3500 C CD  . LYS D 1 113 ? 167.947 175.223 161.522 1.00 31.25 ? 113 LYS D CD  1 
ATOM 3501 C CE  . LYS D 1 113 ? 168.958 175.881 162.446 1.00 36.76 ? 113 LYS D CE  1 
ATOM 3502 N NZ  . LYS D 1 113 ? 170.096 176.479 161.694 1.00 38.57 ? 113 LYS D NZ  1 
ATOM 3503 N N   . HIS D 1 114 ? 163.097 175.889 162.006 1.00 33.67 ? 114 HIS D N   1 
ATOM 3504 C CA  . HIS D 1 114 ? 162.525 177.103 162.571 1.00 34.05 ? 114 HIS D CA  1 
ATOM 3505 C C   . HIS D 1 114 ? 161.085 177.269 162.114 1.00 31.66 ? 114 HIS D C   1 
ATOM 3506 O O   . HIS D 1 114 ? 160.792 177.163 160.918 1.00 37.45 ? 114 HIS D O   1 
ATOM 3507 C CB  . HIS D 1 114 ? 163.347 178.333 162.175 1.00 32.62 ? 114 HIS D CB  1 
ATOM 3508 C CG  . HIS D 1 114 ? 164.695 178.391 162.824 1.00 30.52 ? 114 HIS D CG  1 
ATOM 3509 N ND1 . HIS D 1 114 ? 165.059 177.557 163.858 1.00 31.54 ? 114 HIS D ND1 1 
ATOM 3510 C CD2 . HIS D 1 114 ? 165.769 179.180 162.580 1.00 37.57 ? 114 HIS D CD2 1 
ATOM 3511 C CE1 . HIS D 1 114 ? 166.297 177.832 164.228 1.00 32.97 ? 114 HIS D CE1 1 
ATOM 3512 N NE2 . HIS D 1 114 ? 166.751 178.812 163.467 1.00 41.34 ? 114 HIS D NE2 1 
ATOM 3513 N N   . VAL D 1 115 ? 160.194 177.526 163.066 1.00 18.65 ? 115 VAL D N   1 
ATOM 3514 C CA  . VAL D 1 115 ? 158.795 177.844 162.792 1.00 20.95 ? 115 VAL D CA  1 
ATOM 3515 C C   . VAL D 1 115 ? 158.535 179.205 163.424 1.00 29.71 ? 115 VAL D C   1 
ATOM 3516 O O   . VAL D 1 115 ? 158.220 179.303 164.614 1.00 24.09 ? 115 VAL D O   1 
ATOM 3517 C CB  . VAL D 1 115 ? 157.834 176.783 163.337 1.00 22.37 ? 115 VAL D CB  1 
ATOM 3518 C CG1 . VAL D 1 115 ? 156.427 177.026 162.815 1.00 20.55 ? 115 VAL D CG1 1 
ATOM 3519 C CG2 . VAL D 1 115 ? 158.314 175.392 162.966 1.00 21.59 ? 115 VAL D CG2 1 
ATOM 3520 N N   . ALA D 1 116 ? 158.666 180.266 162.631 1.00 28.27 ? 116 ALA D N   1 
ATOM 3521 C CA  . ALA D 1 116 ? 158.505 181.633 163.110 1.00 19.56 ? 116 ALA D CA  1 
ATOM 3522 C C   . ALA D 1 116 ? 157.291 182.258 162.442 1.00 22.30 ? 116 ALA D C   1 
ATOM 3523 O O   . ALA D 1 116 ? 157.250 182.378 161.213 1.00 21.11 ? 116 ALA D O   1 
ATOM 3524 C CB  . ALA D 1 116 ? 159.758 182.464 162.831 1.00 24.56 ? 116 ALA D CB  1 
ATOM 3525 N N   . GLY D 1 117 ? 156.310 182.652 163.248 1.00 23.46 ? 117 GLY D N   1 
ATOM 3526 C CA  . GLY D 1 117 ? 155.133 183.332 162.729 1.00 22.14 ? 117 GLY D CA  1 
ATOM 3527 C C   . GLY D 1 117 ? 154.362 182.532 161.704 1.00 15.74 ? 117 GLY D C   1 
ATOM 3528 O O   . GLY D 1 117 ? 153.812 183.109 160.758 1.00 20.89 ? 117 GLY D O   1 
ATOM 3529 N N   . ALA D 1 118 ? 154.286 181.217 161.882 1.00 16.73 ? 118 ALA D N   1 
ATOM 3530 C CA  . ALA D 1 118 ? 153.738 180.334 160.863 1.00 17.08 ? 118 ALA D CA  1 
ATOM 3531 C C   . ALA D 1 118 ? 152.945 179.226 161.546 1.00 12.57 ? 118 ALA D C   1 
ATOM 3532 O O   . ALA D 1 118 ? 152.652 179.285 162.743 1.00 17.19 ? 118 ALA D O   1 
ATOM 3533 C CB  . ALA D 1 118 ? 154.861 179.779 159.978 1.00 19.48 ? 118 ALA D CB  1 
ATOM 3534 N N   . ALA D 1 119 ? 152.580 178.213 160.764 1.00 15.85 ? 119 ALA D N   1 
ATOM 3535 C CA  . ALA D 1 119 ? 151.909 177.027 161.271 1.00 21.52 ? 119 ALA D CA  1 
ATOM 3536 C C   . ALA D 1 119 ? 152.552 175.802 160.641 1.00 22.91 ? 119 ALA D C   1 
ATOM 3537 O O   . ALA D 1 119 ? 152.861 175.801 159.447 1.00 25.54 ? 119 ALA D O   1 
ATOM 3538 C CB  . ALA D 1 119 ? 150.408 177.051 160.967 1.00 26.27 ? 119 ALA D CB  1 
ATOM 3539 N N   . ALA D 1 120 ? 152.749 174.762 161.446 1.00 24.69 ? 120 ALA D N   1 
ATOM 3540 C CA  . ALA D 1 120 ? 153.413 173.562 160.961 1.00 22.52 ? 120 ALA D CA  1 
ATOM 3541 C C   . ALA D 1 120 ? 153.017 172.381 161.832 1.00 20.24 ? 120 ALA D C   1 
ATOM 3542 O O   . ALA D 1 120 ? 152.478 172.547 162.930 1.00 15.88 ? 120 ALA D O   1 
ATOM 3543 C CB  . ALA D 1 120 ? 154.934 173.736 160.938 1.00 22.31 ? 120 ALA D CB  1 
ATOM 3544 N N   . ALA D 1 121 ? 153.292 171.181 161.318 1.00 26.64 ? 121 ALA D N   1 
ATOM 3545 C CA  . ALA D 1 121 ? 153.017 169.926 162.019 1.00 20.64 ? 121 ALA D CA  1 
ATOM 3546 C C   . ALA D 1 121 ? 151.552 169.825 162.438 1.00 14.52 ? 121 ALA D C   1 
ATOM 3547 O O   . ALA D 1 121 ? 151.233 169.406 163.552 1.00 24.01 ? 121 ALA D O   1 
ATOM 3548 C CB  . ALA D 1 121 ? 153.943 169.753 163.225 1.00 21.13 ? 121 ALA D CB  1 
ATOM 3549 N N   . GLY D 1 122 ? 150.655 170.208 161.534 1.00 16.58 ? 122 GLY D N   1 
ATOM 3550 C CA  . GLY D 1 122 ? 149.230 170.094 161.776 1.00 17.78 ? 122 GLY D CA  1 
ATOM 3551 C C   . GLY D 1 122 ? 148.709 170.956 162.906 1.00 27.05 ? 122 GLY D C   1 
ATOM 3552 O O   . GLY D 1 122 ? 147.937 170.487 163.748 1.00 25.18 ? 122 GLY D O   1 
ATOM 3553 N N   . ALA D 1 123 ? 149.117 172.222 162.932 1.00 29.98 ? 123 ALA D N   1 
ATOM 3554 C CA  . ALA D 1 123 ? 148.729 173.157 163.976 1.00 17.91 ? 123 ALA D CA  1 
ATOM 3555 C C   . ALA D 1 123 ? 147.918 174.298 163.378 1.00 23.11 ? 123 ALA D C   1 
ATOM 3556 O O   . ALA D 1 123 ? 148.193 174.750 162.263 1.00 27.15 ? 123 ALA D O   1 
ATOM 3557 C CB  . ALA D 1 123 ? 149.960 173.708 164.695 1.00 14.96 ? 123 ALA D CB  1 
ATOM 3558 N N   . VAL D 1 124 ? 146.918 174.764 164.124 1.00 22.29 ? 124 VAL D N   1 
ATOM 3559 C CA  . VAL D 1 124 ? 146.025 175.828 163.679 1.00 22.66 ? 124 VAL D CA  1 
ATOM 3560 C C   . VAL D 1 124 ? 146.343 177.093 164.463 1.00 21.01 ? 124 VAL D C   1 
ATOM 3561 O O   . VAL D 1 124 ? 146.348 177.079 165.698 1.00 29.05 ? 124 VAL D O   1 
ATOM 3562 C CB  . VAL D 1 124 ? 144.547 175.436 163.852 1.00 12.52 ? 124 VAL D CB  1 
ATOM 3563 C CG1 . VAL D 1 124 ? 143.664 176.331 163.002 1.00 22.96 ? 124 VAL D CG1 1 
ATOM 3564 C CG2 . VAL D 1 124 ? 144.343 173.978 163.486 1.00 21.31 ? 124 VAL D CG2 1 
ATOM 3565 N N   . VAL D 1 125 ? 146.613 178.181 163.749 1.00 23.70 ? 125 VAL D N   1 
ATOM 3566 C CA  . VAL D 1 125 ? 146.913 179.470 164.400 1.00 23.30 ? 125 VAL D CA  1 
ATOM 3567 C C   . VAL D 1 125 ? 145.583 180.202 164.540 1.00 25.73 ? 125 VAL D C   1 
ATOM 3568 O O   . VAL D 1 125 ? 145.209 181.059 163.738 1.00 20.16 ? 125 VAL D O   1 
ATOM 3569 C CB  . VAL D 1 125 ? 147.956 180.281 163.629 1.00 15.60 ? 125 VAL D CB  1 
ATOM 3570 C CG1 . VAL D 1 125 ? 148.356 181.514 164.424 1.00 18.99 ? 125 VAL D CG1 1 
ATOM 3571 C CG2 . VAL D 1 125 ? 149.171 179.429 163.328 1.00 19.98 ? 125 VAL D CG2 1 
ATOM 3572 N N   . GLY D 1 126 ? 144.859 179.871 165.603 1.00 32.52 ? 126 GLY D N   1 
ATOM 3573 C CA  . GLY D 1 126 ? 143.711 180.662 165.999 1.00 31.95 ? 126 GLY D CA  1 
ATOM 3574 C C   . GLY D 1 126 ? 142.393 180.366 165.314 1.00 27.90 ? 126 GLY D C   1 
ATOM 3575 O O   . GLY D 1 126 ? 142.298 180.380 164.084 1.00 20.23 ? 126 GLY D O   1 
ATOM 3576 N N   . GLY D 1 127 ? 141.364 180.102 166.116 1.00 34.95 ? 127 GLY D N   1 
ATOM 3577 C CA  . GLY D 1 127 ? 139.996 180.098 165.640 1.00 24.24 ? 127 GLY D CA  1 
ATOM 3578 C C   . GLY D 1 127 ? 139.275 181.320 166.171 1.00 23.88 ? 127 GLY D C   1 
ATOM 3579 O O   . GLY D 1 127 ? 138.987 181.396 167.369 1.00 26.23 ? 127 GLY D O   1 
ATOM 3580 N N   . LEU D 1 128 ? 138.986 182.280 165.291 1.00 28.08 ? 128 LEU D N   1 
ATOM 3581 C CA  . LEU D 1 128 ? 138.562 183.622 165.699 1.00 27.75 ? 128 LEU D CA  1 
ATOM 3582 C C   . LEU D 1 128 ? 139.581 184.249 166.644 1.00 20.50 ? 128 LEU D C   1 
ATOM 3583 O O   . LEU D 1 128 ? 139.228 184.939 167.602 1.00 30.31 ? 128 LEU D O   1 
ATOM 3584 C CB  . LEU D 1 128 ? 137.168 183.612 166.329 1.00 24.56 ? 128 LEU D CB  1 
ATOM 3585 C CG  . LEU D 1 128 ? 135.984 183.481 165.377 1.00 31.30 ? 128 LEU D CG  1 
ATOM 3586 C CD1 . LEU D 1 128 ? 134.705 183.204 166.140 1.00 26.36 ? 128 LEU D CD1 1 
ATOM 3587 C CD2 . LEU D 1 128 ? 135.852 184.752 164.571 1.00 31.54 ? 128 LEU D CD2 1 
ATOM 3588 N N   . GLY D 1 129 ? 140.859 184.013 166.364 1.00 18.68 ? 129 GLY D N   1 
ATOM 3589 C CA  . GLY D 1 129 ? 141.928 184.511 167.203 1.00 20.43 ? 129 GLY D CA  1 
ATOM 3590 C C   . GLY D 1 129 ? 143.295 184.259 166.605 1.00 18.98 ? 129 GLY D C   1 
ATOM 3591 O O   . GLY D 1 129 ? 143.442 184.190 165.381 1.00 27.51 ? 129 GLY D O   1 
ATOM 3592 N N   . GLY D 1 130 ? 144.303 184.117 167.459 1.00 18.01 ? 130 GLY D N   1 
ATOM 3593 C CA  . GLY D 1 130 ? 145.658 183.909 166.996 1.00 18.72 ? 130 GLY D CA  1 
ATOM 3594 C C   . GLY D 1 130 ? 146.591 185.002 167.468 1.00 22.00 ? 130 GLY D C   1 
ATOM 3595 O O   . GLY D 1 130 ? 146.838 185.140 168.670 1.00 23.80 ? 130 GLY D O   1 
ATOM 3596 N N   . TYR D 1 131 ? 147.114 185.787 166.532 1.00 36.73 ? 131 TYR D N   1 
ATOM 3597 C CA  . TYR D 1 131 ? 147.973 186.926 166.841 1.00 37.70 ? 131 TYR D CA  1 
ATOM 3598 C C   . TYR D 1 131 ? 147.245 188.170 166.347 1.00 35.99 ? 131 TYR D C   1 
ATOM 3599 O O   . TYR D 1 131 ? 147.463 188.633 165.224 1.00 30.29 ? 131 TYR D O   1 
ATOM 3600 C CB  . TYR D 1 131 ? 149.353 186.764 166.210 1.00 31.46 ? 131 TYR D CB  1 
ATOM 3601 C CG  . TYR D 1 131 ? 150.175 185.686 166.879 1.00 33.10 ? 131 TYR D CG  1 
ATOM 3602 C CD1 . TYR D 1 131 ? 149.928 184.344 166.625 1.00 33.66 ? 131 TYR D CD1 1 
ATOM 3603 C CD2 . TYR D 1 131 ? 151.180 186.009 167.782 1.00 34.31 ? 131 TYR D CD2 1 
ATOM 3604 C CE1 . TYR D 1 131 ? 150.666 183.354 167.239 1.00 29.12 ? 131 TYR D CE1 1 
ATOM 3605 C CE2 . TYR D 1 131 ? 151.924 185.024 168.403 1.00 35.75 ? 131 TYR D CE2 1 
ATOM 3606 C CZ  . TYR D 1 131 ? 151.661 183.698 168.128 1.00 36.00 ? 131 TYR D CZ  1 
ATOM 3607 O OH  . TYR D 1 131 ? 152.393 182.708 168.741 1.00 36.25 ? 131 TYR D OH  1 
ATOM 3608 N N   . MET D 1 132 ? 146.376 188.708 167.197 1.00 41.84 ? 132 MET D N   1 
ATOM 3609 C CA  . MET D 1 132 ? 145.502 189.827 166.859 1.00 40.74 ? 132 MET D CA  1 
ATOM 3610 C C   . MET D 1 132 ? 145.740 190.924 167.892 1.00 36.12 ? 132 MET D C   1 
ATOM 3611 O O   . MET D 1 132 ? 145.011 191.027 168.880 1.00 39.09 ? 132 MET D O   1 
ATOM 3612 C CB  . MET D 1 132 ? 144.042 189.376 166.830 1.00 38.98 ? 132 MET D CB  1 
ATOM 3613 C CG  . MET D 1 132 ? 143.722 188.412 165.697 1.00 34.61 ? 132 MET D CG  1 
ATOM 3614 S SD  . MET D 1 132 ? 142.025 187.808 165.727 1.00 52.81 ? 132 MET D SD  1 
ATOM 3615 C CE  . MET D 1 132 ? 141.132 189.273 165.223 1.00 46.16 ? 132 MET D CE  1 
ATOM 3616 N N   . LEU D 1 133 ? 146.754 191.757 167.642 1.00 34.63 ? 133 LEU D N   1 
ATOM 3617 C CA  . LEU D 1 133 ? 147.174 192.746 168.629 1.00 32.27 ? 133 LEU D CA  1 
ATOM 3618 C C   . LEU D 1 133 ? 146.048 193.720 168.956 1.00 37.58 ? 133 LEU D C   1 
ATOM 3619 O O   . LEU D 1 133 ? 145.708 193.923 170.126 1.00 43.85 ? 133 LEU D O   1 
ATOM 3620 C CB  . LEU D 1 133 ? 148.411 193.489 168.117 1.00 37.63 ? 133 LEU D CB  1 
ATOM 3621 C CG  . LEU D 1 133 ? 149.142 194.437 169.066 1.00 38.15 ? 133 LEU D CG  1 
ATOM 3622 C CD1 . LEU D 1 133 ? 150.627 194.443 168.759 1.00 40.68 ? 133 LEU D CD1 1 
ATOM 3623 C CD2 . LEU D 1 133 ? 148.580 195.840 168.934 1.00 41.94 ? 133 LEU D CD2 1 
ATOM 3624 N N   . GLY D 1 134 ? 145.460 194.332 167.934 1.00 45.07 ? 134 GLY D N   1 
ATOM 3625 C CA  . GLY D 1 134 ? 144.347 195.236 168.145 1.00 39.06 ? 134 GLY D CA  1 
ATOM 3626 C C   . GLY D 1 134 ? 143.074 194.727 167.503 1.00 43.64 ? 134 GLY D C   1 
ATOM 3627 O O   . GLY D 1 134 ? 142.958 194.710 166.275 1.00 54.53 ? 134 GLY D O   1 
ATOM 3628 N N   . SER D 1 135 ? 142.110 194.311 168.320 1.00 27.65 ? 135 SER D N   1 
ATOM 3629 C CA  . SER D 1 135 ? 140.882 193.727 167.806 1.00 34.47 ? 135 SER D CA  1 
ATOM 3630 C C   . SER D 1 135 ? 139.694 194.233 168.608 1.00 36.67 ? 135 SER D C   1 
ATOM 3631 O O   . SER D 1 135 ? 139.820 194.639 169.766 1.00 42.71 ? 135 SER D O   1 
ATOM 3632 C CB  . SER D 1 135 ? 140.929 192.194 167.844 1.00 36.98 ? 135 SER D CB  1 
ATOM 3633 O OG  . SER D 1 135 ? 139.890 191.636 167.060 1.00 39.23 ? 135 SER D OG  1 
ATOM 3634 N N   . ALA D 1 136 ? 138.529 194.205 167.965 1.00 30.93 ? 136 ALA D N   1 
ATOM 3635 C CA  . ALA D 1 136 ? 137.274 194.579 168.611 1.00 36.52 ? 136 ALA D CA  1 
ATOM 3636 C C   . ALA D 1 136 ? 136.165 193.799 167.924 1.00 37.11 ? 136 ALA D C   1 
ATOM 3637 O O   . ALA D 1 136 ? 135.810 194.103 166.781 1.00 46.08 ? 136 ALA D O   1 
ATOM 3638 C CB  . ALA D 1 136 ? 137.031 196.082 168.525 1.00 35.70 ? 136 ALA D CB  1 
ATOM 3639 N N   . MET D 1 137 ? 135.626 192.793 168.609 1.00 21.54 ? 137 MET D N   1 
ATOM 3640 C CA  . MET D 1 137 ? 134.610 191.917 168.044 1.00 27.00 ? 137 MET D CA  1 
ATOM 3641 C C   . MET D 1 137 ? 133.351 191.977 168.895 1.00 28.23 ? 137 MET D C   1 
ATOM 3642 O O   . MET D 1 137 ? 133.404 191.740 170.104 1.00 31.94 ? 137 MET D O   1 
ATOM 3643 C CB  . MET D 1 137 ? 135.123 190.479 167.947 1.00 34.69 ? 137 MET D CB  1 
ATOM 3644 C CG  . MET D 1 137 ? 136.421 190.343 167.168 1.00 36.57 ? 137 MET D CG  1 
ATOM 3645 S SD  . MET D 1 137 ? 137.375 188.886 167.634 1.00 51.85 ? 137 MET D SD  1 
ATOM 3646 C CE  . MET D 1 137 ? 136.333 187.582 166.990 1.00 38.49 ? 137 MET D CE  1 
ATOM 3647 N N   . SER D 1 138 ? 132.224 192.281 168.261 1.00 30.76 ? 138 SER D N   1 
ATOM 3648 C CA  . SER D 1 138 ? 130.940 192.363 168.943 1.00 23.74 ? 138 SER D CA  1 
ATOM 3649 C C   . SER D 1 138 ? 130.188 191.050 168.771 1.00 26.88 ? 138 SER D C   1 
ATOM 3650 O O   . SER D 1 138 ? 130.038 190.559 167.648 1.00 34.27 ? 138 SER D O   1 
ATOM 3651 C CB  . SER D 1 138 ? 130.106 193.527 168.404 1.00 21.06 ? 138 SER D CB  1 
ATOM 3652 O OG  . SER D 1 138 ? 129.761 193.322 167.047 1.00 34.67 ? 138 SER D OG  1 
ATOM 3653 N N   . ARG D 1 139 ? 129.717 190.498 169.884 1.00 23.95 ? 139 ARG D N   1 
ATOM 3654 C CA  . ARG D 1 139 ? 129.019 189.217 169.913 1.00 24.93 ? 139 ARG D CA  1 
ATOM 3655 C C   . ARG D 1 139 ? 129.781 188.107 169.181 1.00 25.46 ? 139 ARG D C   1 
ATOM 3656 O O   . ARG D 1 139 ? 129.271 187.529 168.216 1.00 24.13 ? 139 ARG D O   1 
ATOM 3657 C CB  . ARG D 1 139 ? 127.612 189.363 169.349 1.00 27.75 ? 139 ARG D CB  1 
ATOM 3658 C CG  . ARG D 1 139 ? 126.648 188.277 169.800 1.00 23.96 ? 139 ARG D CG  1 
ATOM 3659 C CD  . ARG D 1 139 ? 125.333 188.867 170.272 1.00 27.63 ? 139 ARG D CD  1 
ATOM 3660 N NE  . ARG D 1 139 ? 124.438 189.174 169.164 1.00 38.05 ? 139 ARG D NE  1 
ATOM 3661 C CZ  . ARG D 1 139 ? 123.531 188.337 168.679 1.00 36.72 ? 139 ARG D CZ  1 
ATOM 3662 N NH1 . ARG D 1 139 ? 123.378 187.121 169.178 1.00 34.68 ? 139 ARG D NH1 1 
ATOM 3663 N NH2 . ARG D 1 139 ? 122.757 188.729 167.672 1.00 24.54 ? 139 ARG D NH2 1 
ATOM 3664 N N   . PRO D 1 140 ? 131.011 187.787 169.612 1.00 30.70 ? 140 PRO D N   1 
ATOM 3665 C CA  . PRO D 1 140 ? 131.719 186.654 169.005 1.00 18.23 ? 140 PRO D CA  1 
ATOM 3666 C C   . PRO D 1 140 ? 131.327 185.340 169.658 1.00 16.25 ? 140 PRO D C   1 
ATOM 3667 O O   . PRO D 1 140 ? 131.520 185.159 170.863 1.00 19.67 ? 140 PRO D O   1 
ATOM 3668 C CB  . PRO D 1 140 ? 133.199 186.991 169.243 1.00 16.75 ? 140 PRO D CB  1 
ATOM 3669 C CG  . PRO D 1 140 ? 133.216 188.230 170.131 1.00 23.33 ? 140 PRO D CG  1 
ATOM 3670 C CD  . PRO D 1 140 ? 131.830 188.433 170.646 1.00 25.51 ? 140 PRO D CD  1 
ATOM 3671 N N   . LEU D 1 141 ? 130.776 184.415 168.875 1.00 17.64 ? 141 LEU D N   1 
ATOM 3672 C CA  . LEU D 1 141 ? 130.191 183.194 169.410 1.00 12.64 ? 141 LEU D CA  1 
ATOM 3673 C C   . LEU D 1 141 ? 130.812 181.975 168.743 1.00 15.71 ? 141 LEU D C   1 
ATOM 3674 O O   . LEU D 1 141 ? 130.900 181.911 167.514 1.00 15.27 ? 141 LEU D O   1 
ATOM 3675 C CB  . LEU D 1 141 ? 128.670 183.193 169.214 1.00 21.43 ? 141 LEU D CB  1 
ATOM 3676 C CG  . LEU D 1 141 ? 127.922 181.867 169.350 1.00 18.81 ? 141 LEU D CG  1 
ATOM 3677 C CD1 . LEU D 1 141 ? 128.156 181.240 170.708 1.00 16.87 ? 141 LEU D CD1 1 
ATOM 3678 C CD2 . LEU D 1 141 ? 126.435 182.068 169.100 1.00 22.15 ? 141 LEU D CD2 1 
ATOM 3679 N N   . ILE D 1 142 ? 131.241 181.016 169.562 1.00 21.87 ? 142 ILE D N   1 
ATOM 3680 C CA  . ILE D 1 142 ? 131.716 179.716 169.101 1.00 10.68 ? 142 ILE D CA  1 
ATOM 3681 C C   . ILE D 1 142 ? 130.980 178.646 169.894 1.00 15.07 ? 142 ILE D C   1 
ATOM 3682 O O   . ILE D 1 142 ? 131.115 178.584 171.122 1.00 28.23 ? 142 ILE D O   1 
ATOM 3683 C CB  . ILE D 1 142 ? 133.235 179.553 169.278 1.00 19.51 ? 142 ILE D CB  1 
ATOM 3684 C CG1 . ILE D 1 142 ? 133.992 180.587 168.446 1.00 30.02 ? 142 ILE D CG1 1 
ATOM 3685 C CG2 . ILE D 1 142 ? 133.667 178.143 168.905 1.00 16.66 ? 142 ILE D CG2 1 
ATOM 3686 C CD1 . ILE D 1 142 ? 135.493 180.389 168.449 1.00 17.00 ? 142 ILE D CD1 1 
ATOM 3687 N N   . HIS D 1 143 ? 130.211 177.805 169.208 1.00 11.23 ? 143 HIS D N   1 
ATOM 3688 C CA  . HIS D 1 143 ? 129.521 176.705 169.878 1.00 19.18 ? 143 HIS D CA  1 
ATOM 3689 C C   . HIS D 1 143 ? 129.518 175.477 168.980 1.00 17.52 ? 143 HIS D C   1 
ATOM 3690 O O   . HIS D 1 143 ? 128.866 175.464 167.935 1.00 24.83 ? 143 HIS D O   1 
ATOM 3691 C CB  . HIS D 1 143 ? 128.098 177.101 170.290 1.00 14.31 ? 143 HIS D CB  1 
ATOM 3692 C CG  . HIS D 1 143 ? 127.197 177.484 169.157 1.00 11.13 ? 143 HIS D CG  1 
ATOM 3693 N ND1 . HIS D 1 143 ? 127.214 178.737 168.582 1.00 28.99 ? 143 HIS D ND1 1 
ATOM 3694 C CD2 . HIS D 1 143 ? 126.218 176.794 168.527 1.00 18.83 ? 143 HIS D CD2 1 
ATOM 3695 C CE1 . HIS D 1 143 ? 126.298 178.794 167.632 1.00 19.62 ? 143 HIS D CE1 1 
ATOM 3696 N NE2 . HIS D 1 143 ? 125.682 177.629 167.577 1.00 29.50 ? 143 HIS D NE2 1 
ATOM 3697 N N   . PHE D 1 144 ? 130.241 174.437 169.397 1.00 14.58 ? 144 PHE D N   1 
ATOM 3698 C CA  . PHE D 1 144 ? 130.283 173.208 168.618 1.00 14.97 ? 144 PHE D CA  1 
ATOM 3699 C C   . PHE D 1 144 ? 128.955 172.464 168.639 1.00 7.79  ? 144 PHE D C   1 
ATOM 3700 O O   . PHE D 1 144 ? 128.682 171.686 167.720 1.00 34.64 ? 144 PHE D O   1 
ATOM 3701 C CB  . PHE D 1 144 ? 131.402 172.302 169.131 1.00 18.95 ? 144 PHE D CB  1 
ATOM 3702 C CG  . PHE D 1 144 ? 132.766 172.691 168.639 1.00 14.78 ? 144 PHE D CG  1 
ATOM 3703 C CD1 . PHE D 1 144 ? 133.397 173.822 169.129 1.00 13.58 ? 144 PHE D CD1 1 
ATOM 3704 C CD2 . PHE D 1 144 ? 133.415 171.929 167.683 1.00 15.27 ? 144 PHE D CD2 1 
ATOM 3705 C CE1 . PHE D 1 144 ? 134.650 174.183 168.678 1.00 17.23 ? 144 PHE D CE1 1 
ATOM 3706 C CE2 . PHE D 1 144 ? 134.671 172.286 167.227 1.00 15.09 ? 144 PHE D CE2 1 
ATOM 3707 C CZ  . PHE D 1 144 ? 135.288 173.415 167.725 1.00 15.67 ? 144 PHE D CZ  1 
ATOM 3708 N N   . GLY D 1 145 ? 128.123 172.691 169.650 1.00 0.00  ? 145 GLY D N   1 
ATOM 3709 C CA  . GLY D 1 145 ? 126.858 171.996 169.744 1.00 9.34  ? 145 GLY D CA  1 
ATOM 3710 C C   . GLY D 1 145 ? 125.841 172.493 168.732 1.00 16.15 ? 145 GLY D C   1 
ATOM 3711 O O   . GLY D 1 145 ? 126.022 173.500 168.048 1.00 9.66  ? 145 GLY D O   1 
ATOM 3712 N N   . ASN D 1 146 ? 124.742 171.748 168.638 1.00 20.42 ? 146 ASN D N   1 
ATOM 3713 C CA  . ASN D 1 146 ? 123.663 172.107 167.731 1.00 21.22 ? 146 ASN D CA  1 
ATOM 3714 C C   . ASN D 1 146 ? 122.989 173.398 168.180 1.00 19.80 ? 146 ASN D C   1 
ATOM 3715 O O   . ASN D 1 146 ? 122.883 173.691 169.374 1.00 22.01 ? 146 ASN D O   1 
ATOM 3716 C CB  . ASN D 1 146 ? 122.634 170.979 167.652 1.00 20.35 ? 146 ASN D CB  1 
ATOM 3717 C CG  . ASN D 1 146 ? 123.223 169.688 167.127 1.00 25.80 ? 146 ASN D CG  1 
ATOM 3718 O OD1 . ASN D 1 146 ? 123.226 169.438 165.922 1.00 25.52 ? 146 ASN D OD1 1 
ATOM 3719 N ND2 . ASN D 1 146 ? 123.726 168.855 168.032 1.00 23.77 ? 146 ASN D ND2 1 
ATOM 3720 N N   . ASP D 1 147 ? 122.528 174.175 167.203 1.00 24.50 ? 147 ASP D N   1 
ATOM 3721 C CA  . ASP D 1 147 ? 121.895 175.463 167.449 1.00 22.90 ? 147 ASP D CA  1 
ATOM 3722 C C   . ASP D 1 147 ? 120.450 175.420 166.975 1.00 18.37 ? 147 ASP D C   1 
ATOM 3723 O O   . ASP D 1 147 ? 120.172 174.994 165.850 1.00 31.21 ? 147 ASP D O   1 
ATOM 3724 C CB  . ASP D 1 147 ? 122.648 176.590 166.741 1.00 21.68 ? 147 ASP D CB  1 
ATOM 3725 C CG  . ASP D 1 147 ? 122.315 177.957 167.305 1.00 30.17 ? 147 ASP D CG  1 
ATOM 3726 O OD1 . ASP D 1 147 ? 121.675 178.019 168.374 1.00 29.97 ? 147 ASP D OD1 1 
ATOM 3727 O OD2 . ASP D 1 147 ? 122.694 178.968 166.678 1.00 38.96 ? 147 ASP D OD2 1 
ATOM 3728 N N   . TYR D 1 148 ? 119.536 175.860 167.838 1.00 19.69 ? 148 TYR D N   1 
ATOM 3729 C CA  . TYR D 1 148 ? 118.125 175.985 167.502 1.00 22.88 ? 148 TYR D CA  1 
ATOM 3730 C C   . TYR D 1 148 ? 117.658 177.381 167.877 1.00 26.71 ? 148 TYR D C   1 
ATOM 3731 O O   . TYR D 1 148 ? 117.911 177.844 168.994 1.00 23.19 ? 148 TYR D O   1 
ATOM 3732 C CB  . TYR D 1 148 ? 117.284 174.928 168.227 1.00 16.87 ? 148 TYR D CB  1 
ATOM 3733 C CG  . TYR D 1 148 ? 115.830 174.896 167.808 1.00 15.05 ? 148 TYR D CG  1 
ATOM 3734 C CD1 . TYR D 1 148 ? 114.898 175.746 168.391 1.00 19.73 ? 148 TYR D CD1 1 
ATOM 3735 C CD2 . TYR D 1 148 ? 115.387 174.014 166.832 1.00 19.74 ? 148 TYR D CD2 1 
ATOM 3736 C CE1 . TYR D 1 148 ? 113.570 175.718 168.014 1.00 22.95 ? 148 TYR D CE1 1 
ATOM 3737 C CE2 . TYR D 1 148 ? 114.060 173.976 166.450 1.00 17.95 ? 148 TYR D CE2 1 
ATOM 3738 C CZ  . TYR D 1 148 ? 113.157 174.832 167.043 1.00 19.49 ? 148 TYR D CZ  1 
ATOM 3739 O OH  . TYR D 1 148 ? 111.835 174.800 166.665 1.00 24.05 ? 148 TYR D OH  1 
ATOM 3740 N N   . GLU D 1 149 ? 116.981 178.049 166.946 1.00 31.72 ? 149 GLU D N   1 
ATOM 3741 C CA  . GLU D 1 149 ? 116.477 179.399 167.162 1.00 26.09 ? 149 GLU D CA  1 
ATOM 3742 C C   . GLU D 1 149 ? 115.042 179.487 166.671 1.00 25.67 ? 149 GLU D C   1 
ATOM 3743 O O   . GLU D 1 149 ? 114.756 179.160 165.514 1.00 34.57 ? 149 GLU D O   1 
ATOM 3744 C CB  . GLU D 1 149 ? 117.347 180.438 166.447 1.00 31.89 ? 149 GLU D CB  1 
ATOM 3745 C CG  . GLU D 1 149 ? 118.715 180.642 167.076 1.00 36.78 ? 149 GLU D CG  1 
ATOM 3746 C CD  . GLU D 1 149 ? 119.497 181.762 166.419 1.00 43.02 ? 149 GLU D CD  1 
ATOM 3747 O OE1 . GLU D 1 149 ? 118.909 182.501 165.602 1.00 35.95 ? 149 GLU D OE1 1 
ATOM 3748 O OE2 . GLU D 1 149 ? 120.701 181.904 166.721 1.00 47.50 ? 149 GLU D OE2 1 
ATOM 3749 N N   . ASP D 1 150 ? 114.144 179.929 167.551 1.00 33.18 ? 150 ASP D N   1 
ATOM 3750 C CA  . ASP D 1 150 ? 112.738 180.165 167.221 1.00 28.31 ? 150 ASP D CA  1 
ATOM 3751 C C   . ASP D 1 150 ? 112.435 181.605 167.626 1.00 30.42 ? 150 ASP D C   1 
ATOM 3752 O O   . ASP D 1 150 ? 111.991 181.865 168.746 1.00 32.11 ? 150 ASP D O   1 
ATOM 3753 C CB  . ASP D 1 150 ? 111.826 179.166 167.925 1.00 29.78 ? 150 ASP D CB  1 
ATOM 3754 C CG  . ASP D 1 150 ? 110.409 179.196 167.391 1.00 33.97 ? 150 ASP D CG  1 
ATOM 3755 O OD1 . ASP D 1 150 ? 110.178 179.841 166.347 1.00 38.41 ? 150 ASP D OD1 1 
ATOM 3756 O OD2 . ASP D 1 150 ? 109.524 178.572 168.014 1.00 38.20 ? 150 ASP D OD2 1 
ATOM 3757 N N   . ARG D 1 151 ? 112.676 182.537 166.708 1.00 35.19 ? 151 ARG D N   1 
ATOM 3758 C CA  . ARG D 1 151 ? 112.585 183.962 166.991 1.00 27.97 ? 151 ARG D CA  1 
ATOM 3759 C C   . ARG D 1 151 ? 111.275 184.526 166.455 1.00 21.74 ? 151 ARG D C   1 
ATOM 3760 O O   . ARG D 1 151 ? 110.894 184.250 165.313 1.00 20.50 ? 151 ARG D O   1 
ATOM 3761 C CB  . ARG D 1 151 ? 113.767 184.712 166.376 1.00 22.91 ? 151 ARG D CB  1 
ATOM 3762 C CG  . ARG D 1 151 ? 115.083 184.504 167.104 1.00 23.72 ? 151 ARG D CG  1 
ATOM 3763 C CD  . ARG D 1 151 ? 116.163 185.420 166.557 1.00 24.37 ? 151 ARG D CD  1 
ATOM 3764 N NE  . ARG D 1 151 ? 117.352 185.428 167.399 1.00 26.76 ? 151 ARG D NE  1 
ATOM 3765 C CZ  . ARG D 1 151 ? 118.413 186.195 167.189 1.00 28.52 ? 151 ARG D CZ  1 
ATOM 3766 N NH1 . ARG D 1 151 ? 118.469 187.033 166.167 1.00 25.66 ? 151 ARG D NH1 1 
ATOM 3767 N NH2 . ARG D 1 151 ? 119.444 186.120 168.026 1.00 30.43 ? 151 ARG D NH2 1 
ATOM 3768 N N   . TYR D 1 152 ? 110.593 185.312 167.287 1.00 25.76 ? 152 TYR D N   1 
ATOM 3769 C CA  . TYR D 1 152 ? 109.379 186.035 166.907 1.00 21.78 ? 152 TYR D CA  1 
ATOM 3770 C C   . TYR D 1 152 ? 109.578 187.477 167.366 1.00 23.68 ? 152 TYR D C   1 
ATOM 3771 O O   . TYR D 1 152 ? 109.251 187.830 168.502 1.00 26.45 ? 152 TYR D O   1 
ATOM 3772 C CB  . TYR D 1 152 ? 108.133 185.394 167.522 1.00 17.43 ? 152 TYR D CB  1 
ATOM 3773 C CG  . TYR D 1 152 ? 106.826 186.097 167.204 1.00 23.10 ? 152 TYR D CG  1 
ATOM 3774 C CD1 . TYR D 1 152 ? 106.725 186.991 166.145 1.00 24.33 ? 152 TYR D CD1 1 
ATOM 3775 C CD2 . TYR D 1 152 ? 105.688 185.855 167.963 1.00 27.63 ? 152 TYR D CD2 1 
ATOM 3776 C CE1 . TYR D 1 152 ? 105.534 187.630 165.860 1.00 25.11 ? 152 TYR D CE1 1 
ATOM 3777 C CE2 . TYR D 1 152 ? 104.492 186.488 167.683 1.00 23.82 ? 152 TYR D CE2 1 
ATOM 3778 C CZ  . TYR D 1 152 ? 104.420 187.374 166.631 1.00 24.64 ? 152 TYR D CZ  1 
ATOM 3779 O OH  . TYR D 1 152 ? 103.231 188.006 166.348 1.00 29.62 ? 152 TYR D OH  1 
ATOM 3780 N N   . TYR D 1 153 ? 110.114 188.306 166.476 1.00 30.47 ? 153 TYR D N   1 
ATOM 3781 C CA  . TYR D 1 153 ? 110.392 189.706 166.765 1.00 26.34 ? 153 TYR D CA  1 
ATOM 3782 C C   . TYR D 1 153 ? 109.290 190.561 166.151 1.00 24.83 ? 153 TYR D C   1 
ATOM 3783 O O   . TYR D 1 153 ? 109.026 190.467 164.948 1.00 30.00 ? 153 TYR D O   1 
ATOM 3784 C CB  . TYR D 1 153 ? 111.758 190.119 166.215 1.00 22.54 ? 153 TYR D CB  1 
ATOM 3785 C CG  . TYR D 1 153 ? 112.945 189.612 167.009 1.00 22.15 ? 153 TYR D CG  1 
ATOM 3786 C CD1 . TYR D 1 153 ? 112.804 188.597 167.946 1.00 25.79 ? 153 TYR D CD1 1 
ATOM 3787 C CD2 . TYR D 1 153 ? 114.209 190.150 166.814 1.00 21.51 ? 153 TYR D CD2 1 
ATOM 3788 C CE1 . TYR D 1 153 ? 113.887 188.134 168.667 1.00 26.52 ? 153 TYR D CE1 1 
ATOM 3789 C CE2 . TYR D 1 153 ? 115.298 189.694 167.530 1.00 22.34 ? 153 TYR D CE2 1 
ATOM 3790 C CZ  . TYR D 1 153 ? 115.133 188.686 168.454 1.00 24.14 ? 153 TYR D CZ  1 
ATOM 3791 O OH  . TYR D 1 153 ? 116.216 188.230 169.169 1.00 30.74 ? 153 TYR D OH  1 
ATOM 3792 N N   . ARG D 1 154 ? 108.650 191.389 166.975 1.00 33.17 ? 154 ARG D N   1 
ATOM 3793 C CA  . ARG D 1 154 ? 107.550 192.232 166.523 1.00 29.35 ? 154 ARG D CA  1 
ATOM 3794 C C   . ARG D 1 154 ? 107.730 193.633 167.081 1.00 32.92 ? 154 ARG D C   1 
ATOM 3795 O O   . ARG D 1 154 ? 107.791 193.813 168.301 1.00 30.84 ? 154 ARG D O   1 
ATOM 3796 C CB  . ARG D 1 154 ? 106.197 191.656 166.953 1.00 26.79 ? 154 ARG D CB  1 
ATOM 3797 C CG  . ARG D 1 154 ? 105.004 192.472 166.487 1.00 35.23 ? 154 ARG D CG  1 
ATOM 3798 C CD  . ARG D 1 154 ? 103.698 191.864 166.968 1.00 38.18 ? 154 ARG D CD  1 
ATOM 3799 N NE  . ARG D 1 154 ? 102.540 192.590 166.460 1.00 41.54 ? 154 ARG D NE  1 
ATOM 3800 C CZ  . ARG D 1 154 ? 101.281 192.246 166.691 1.00 43.21 ? 154 ARG D CZ  1 
ATOM 3801 N NH1 . ARG D 1 154 ? 100.977 191.187 167.423 1.00 41.26 ? 154 ARG D NH1 1 
ATOM 3802 N NH2 . ARG D 1 154 ? 100.302 192.984 166.176 1.00 38.29 ? 154 ARG D NH2 1 
ATOM 3803 N N   . GLU D 1 155 ? 107.812 194.619 166.185 1.00 40.15 ? 155 GLU D N   1 
ATOM 3804 C CA  . GLU D 1 155 ? 107.876 196.035 166.554 1.00 35.54 ? 155 GLU D CA  1 
ATOM 3805 C C   . GLU D 1 155 ? 109.050 196.326 167.487 1.00 34.27 ? 155 GLU D C   1 
ATOM 3806 O O   . GLU D 1 155 ? 108.945 197.132 168.413 1.00 37.52 ? 155 GLU D O   1 
ATOM 3807 C CB  . GLU D 1 155 ? 106.559 196.501 167.179 1.00 35.18 ? 155 GLU D CB  1 
ATOM 3808 C CG  . GLU D 1 155 ? 105.387 196.518 166.213 1.00 37.54 ? 155 GLU D CG  1 
ATOM 3809 C CD  . GLU D 1 155 ? 104.051 196.643 166.919 1.00 43.67 ? 155 GLU D CD  1 
ATOM 3810 O OE1 . GLU D 1 155 ? 103.836 195.924 167.918 1.00 43.82 ? 155 GLU D OE1 1 
ATOM 3811 O OE2 . GLU D 1 155 ? 103.217 197.459 166.476 1.00 40.89 ? 155 GLU D OE2 1 
ATOM 3812 N N   . ASN D 1 156 ? 110.181 195.676 167.235 1.00 28.51 ? 156 ASN D N   1 
ATOM 3813 C CA  . ASN D 1 156 ? 111.385 195.865 168.033 1.00 29.54 ? 156 ASN D CA  1 
ATOM 3814 C C   . ASN D 1 156 ? 112.302 196.863 167.340 1.00 30.86 ? 156 ASN D C   1 
ATOM 3815 O O   . ASN D 1 156 ? 112.603 196.717 166.151 1.00 40.39 ? 156 ASN D O   1 
ATOM 3816 C CB  . ASN D 1 156 ? 112.111 194.538 168.250 1.00 31.36 ? 156 ASN D CB  1 
ATOM 3817 C CG  . ASN D 1 156 ? 111.218 193.482 168.866 1.00 30.47 ? 156 ASN D CG  1 
ATOM 3818 O OD1 . ASN D 1 156 ? 110.610 192.678 168.160 1.00 38.20 ? 156 ASN D OD1 1 
ATOM 3819 N ND2 . ASN D 1 156 ? 111.129 193.481 170.190 1.00 35.25 ? 156 ASN D ND2 1 
ATOM 3820 N N   . MET D 1 157 ? 112.741 197.874 168.085 1.00 36.16 ? 157 MET D N   1 
ATOM 3821 C CA  . MET D 1 157 ? 113.609 198.926 167.560 1.00 38.76 ? 157 MET D CA  1 
ATOM 3822 C C   . MET D 1 157 ? 115.044 198.602 167.958 1.00 37.37 ? 157 MET D C   1 
ATOM 3823 O O   . MET D 1 157 ? 115.440 198.796 169.111 1.00 41.20 ? 157 MET D O   1 
ATOM 3824 C CB  . MET D 1 157 ? 113.177 200.293 168.078 1.00 36.94 ? 157 MET D CB  1 
ATOM 3825 C CG  . MET D 1 157 ? 113.325 201.417 167.064 1.00 39.70 ? 157 MET D CG  1 
ATOM 3826 S SD  . MET D 1 157 ? 115.047 201.836 166.731 1.00 53.93 ? 157 MET D SD  1 
ATOM 3827 C CE  . MET D 1 157 ? 115.352 203.056 168.004 1.00 40.79 ? 157 MET D CE  1 
ATOM 3828 N N   . TYR D 1 158 ? 115.823 198.109 167.001 1.00 32.10 ? 158 TYR D N   1 
ATOM 3829 C CA  . TYR D 1 158 ? 117.230 197.781 167.214 1.00 23.33 ? 158 TYR D CA  1 
ATOM 3830 C C   . TYR D 1 158 ? 118.069 198.911 166.632 1.00 30.62 ? 158 TYR D C   1 
ATOM 3831 O O   . TYR D 1 158 ? 118.222 199.023 165.413 1.00 40.92 ? 158 TYR D O   1 
ATOM 3832 C CB  . TYR D 1 158 ? 117.576 196.441 166.575 1.00 31.67 ? 158 TYR D CB  1 
ATOM 3833 C CG  . TYR D 1 158 ? 117.227 195.246 167.433 1.00 28.88 ? 158 TYR D CG  1 
ATOM 3834 C CD1 . TYR D 1 158 ? 118.144 194.725 168.335 1.00 26.36 ? 158 TYR D CD1 1 
ATOM 3835 C CD2 . TYR D 1 158 ? 115.982 194.641 167.339 1.00 24.65 ? 158 TYR D CD2 1 
ATOM 3836 C CE1 . TYR D 1 158 ? 117.830 193.635 169.121 1.00 28.95 ? 158 TYR D CE1 1 
ATOM 3837 C CE2 . TYR D 1 158 ? 115.659 193.549 168.121 1.00 26.22 ? 158 TYR D CE2 1 
ATOM 3838 C CZ  . TYR D 1 158 ? 116.586 193.051 169.009 1.00 31.59 ? 158 TYR D CZ  1 
ATOM 3839 O OH  . TYR D 1 158 ? 116.271 191.965 169.790 1.00 31.35 ? 158 TYR D OH  1 
ATOM 3840 N N   . ARG D 1 159 ? 118.616 199.751 167.507 1.00 31.91 ? 159 ARG D N   1 
ATOM 3841 C CA  . ARG D 1 159 ? 119.437 200.887 167.102 1.00 31.02 ? 159 ARG D CA  1 
ATOM 3842 C C   . ARG D 1 159 ? 120.904 200.519 167.291 1.00 34.81 ? 159 ARG D C   1 
ATOM 3843 O O   . ARG D 1 159 ? 121.384 200.422 168.424 1.00 38.90 ? 159 ARG D O   1 
ATOM 3844 C CB  . ARG D 1 159 ? 119.072 202.134 167.903 1.00 34.09 ? 159 ARG D CB  1 
ATOM 3845 C CG  . ARG D 1 159 ? 119.503 203.434 167.246 1.00 35.39 ? 159 ARG D CG  1 
ATOM 3846 C CD  . ARG D 1 159 ? 118.906 204.637 167.954 1.00 31.48 ? 159 ARG D CD  1 
ATOM 3847 N NE  . ARG D 1 159 ? 118.998 205.844 167.143 1.00 35.04 ? 159 ARG D NE  1 
ATOM 3848 C CZ  . ARG D 1 159 ? 118.114 206.198 166.220 1.00 39.92 ? 159 ARG D CZ  1 
ATOM 3849 N NH1 . ARG D 1 159 ? 117.048 205.456 165.965 1.00 39.44 ? 159 ARG D NH1 1 
ATOM 3850 N NH2 . ARG D 1 159 ? 118.302 207.323 165.538 1.00 35.94 ? 159 ARG D NH2 1 
ATOM 3851 N N   . TYR D 1 160 ? 121.607 200.324 166.180 1.00 20.38 ? 160 TYR D N   1 
ATOM 3852 C CA  . TYR D 1 160 ? 123.019 199.959 166.176 1.00 21.14 ? 160 TYR D CA  1 
ATOM 3853 C C   . TYR D 1 160 ? 123.329 198.737 167.046 1.00 24.15 ? 160 TYR D C   1 
ATOM 3854 O O   . TYR D 1 160 ? 124.131 198.823 167.982 1.00 29.58 ? 160 TYR D O   1 
ATOM 3855 C CB  . TYR D 1 160 ? 123.873 201.146 166.601 1.00 25.04 ? 160 TYR D CB  1 
ATOM 3856 C CG  . TYR D 1 160 ? 123.932 202.270 165.591 1.00 28.24 ? 160 TYR D CG  1 
ATOM 3857 C CD1 . TYR D 1 160 ? 122.873 203.157 165.445 1.00 28.18 ? 160 TYR D CD1 1 
ATOM 3858 C CD2 . TYR D 1 160 ? 125.051 202.451 164.789 1.00 30.07 ? 160 TYR D CD2 1 
ATOM 3859 C CE1 . TYR D 1 160 ? 122.925 204.187 164.525 1.00 26.68 ? 160 TYR D CE1 1 
ATOM 3860 C CE2 . TYR D 1 160 ? 125.112 203.478 163.867 1.00 26.95 ? 160 TYR D CE2 1 
ATOM 3861 C CZ  . TYR D 1 160 ? 124.046 204.343 163.738 1.00 25.00 ? 160 TYR D CZ  1 
ATOM 3862 O OH  . TYR D 1 160 ? 124.102 205.367 162.822 1.00 31.55 ? 160 TYR D OH  1 
ATOM 3863 N N   . PRO D 1 161 ? 122.716 197.585 166.768 1.00 20.42 ? 161 PRO D N   1 
ATOM 3864 C CA  . PRO D 1 161 ? 123.069 196.375 167.519 1.00 18.89 ? 161 PRO D CA  1 
ATOM 3865 C C   . PRO D 1 161 ? 124.365 195.755 167.023 1.00 21.09 ? 161 PRO D C   1 
ATOM 3866 O O   . PRO D 1 161 ? 124.645 195.725 165.822 1.00 24.28 ? 161 PRO D O   1 
ATOM 3867 C CB  . PRO D 1 161 ? 121.871 195.449 167.277 1.00 13.88 ? 161 PRO D CB  1 
ATOM 3868 C CG  . PRO D 1 161 ? 121.365 195.847 165.952 1.00 20.22 ? 161 PRO D CG  1 
ATOM 3869 C CD  . PRO D 1 161 ? 121.658 197.318 165.775 1.00 19.05 ? 161 PRO D CD  1 
ATOM 3870 N N   . ASN D 1 162 ? 125.154 195.255 167.975 1.00 20.79 ? 162 ASN D N   1 
ATOM 3871 C CA  . ASN D 1 162 ? 126.459 194.653 167.694 1.00 15.77 ? 162 ASN D CA  1 
ATOM 3872 C C   . ASN D 1 162 ? 127.355 195.617 166.922 1.00 15.47 ? 162 ASN D C   1 
ATOM 3873 O O   . ASN D 1 162 ? 128.066 195.234 165.990 1.00 27.93 ? 162 ASN D O   1 
ATOM 3874 C CB  . ASN D 1 162 ? 126.306 193.327 166.947 1.00 19.21 ? 162 ASN D CB  1 
ATOM 3875 C CG  . ASN D 1 162 ? 125.379 192.362 167.658 1.00 23.01 ? 162 ASN D CG  1 
ATOM 3876 O OD1 . ASN D 1 162 ? 125.592 192.020 168.820 1.00 23.24 ? 162 ASN D OD1 1 
ATOM 3877 N ND2 . ASN D 1 162 ? 124.342 191.914 166.960 1.00 28.10 ? 162 ASN D ND2 1 
ATOM 3878 N N   . GLN D 1 163 ? 127.320 196.887 167.316 1.00 19.47 ? 163 GLN D N   1 
ATOM 3879 C CA  . GLN D 1 163 ? 128.107 197.915 166.652 1.00 23.52 ? 163 GLN D CA  1 
ATOM 3880 C C   . GLN D 1 163 ? 129.545 197.883 167.152 1.00 28.33 ? 163 GLN D C   1 
ATOM 3881 O O   . GLN D 1 163 ? 129.791 197.810 168.360 1.00 32.85 ? 163 GLN D O   1 
ATOM 3882 C CB  . GLN D 1 163 ? 127.492 199.293 166.890 1.00 17.53 ? 163 GLN D CB  1 
ATOM 3883 C CG  . GLN D 1 163 ? 127.796 200.307 165.801 1.00 25.39 ? 163 GLN D CG  1 
ATOM 3884 C CD  . GLN D 1 163 ? 128.886 201.281 166.199 1.00 28.85 ? 163 GLN D CD  1 
ATOM 3885 O OE1 . GLN D 1 163 ? 129.520 201.127 167.244 1.00 29.13 ? 163 GLN D OE1 1 
ATOM 3886 N NE2 . GLN D 1 163 ? 129.110 202.289 165.368 1.00 31.23 ? 163 GLN D NE2 1 
ATOM 3887 N N   . VAL D 1 164 ? 130.492 197.936 166.222 1.00 28.26 ? 164 VAL D N   1 
ATOM 3888 C CA  . VAL D 1 164 ? 131.915 197.950 166.538 1.00 21.81 ? 164 VAL D CA  1 
ATOM 3889 C C   . VAL D 1 164 ? 132.437 199.334 166.176 1.00 29.00 ? 164 VAL D C   1 
ATOM 3890 O O   . VAL D 1 164 ? 132.776 199.601 165.018 1.00 32.82 ? 164 VAL D O   1 
ATOM 3891 C CB  . VAL D 1 164 ? 132.682 196.852 165.795 1.00 31.55 ? 164 VAL D CB  1 
ATOM 3892 C CG1 . VAL D 1 164 ? 134.126 196.808 166.267 1.00 23.51 ? 164 VAL D CG1 1 
ATOM 3893 C CG2 . VAL D 1 164 ? 132.010 195.505 165.995 1.00 30.10 ? 164 VAL D CG2 1 
ATOM 3894 N N   . TYR D 1 165 ? 132.507 200.224 167.167 1.00 34.19 ? 165 TYR D N   1 
ATOM 3895 C CA  . TYR D 1 165 ? 133.051 201.565 166.963 1.00 28.28 ? 165 TYR D CA  1 
ATOM 3896 C C   . TYR D 1 165 ? 134.561 201.498 167.168 1.00 33.76 ? 165 TYR D C   1 
ATOM 3897 O O   . TYR D 1 165 ? 135.097 201.807 168.234 1.00 40.58 ? 165 TYR D O   1 
ATOM 3898 C CB  . TYR D 1 165 ? 132.389 202.566 167.901 1.00 29.51 ? 165 TYR D CB  1 
ATOM 3899 C CG  . TYR D 1 165 ? 132.336 203.971 167.347 1.00 33.82 ? 165 TYR D CG  1 
ATOM 3900 C CD1 . TYR D 1 165 ? 131.300 204.370 166.513 1.00 33.51 ? 165 TYR D CD1 1 
ATOM 3901 C CD2 . TYR D 1 165 ? 133.325 204.896 167.653 1.00 33.01 ? 165 TYR D CD2 1 
ATOM 3902 C CE1 . TYR D 1 165 ? 131.249 205.653 166.002 1.00 32.79 ? 165 TYR D CE1 1 
ATOM 3903 C CE2 . TYR D 1 165 ? 133.283 206.181 167.146 1.00 29.38 ? 165 TYR D CE2 1 
ATOM 3904 C CZ  . TYR D 1 165 ? 132.243 206.554 166.321 1.00 29.63 ? 165 TYR D CZ  1 
ATOM 3905 O OH  . TYR D 1 165 ? 132.196 207.833 165.815 1.00 33.49 ? 165 TYR D OH  1 
ATOM 3906 N N   . TYR D 1 166 ? 135.255 201.078 166.112 1.00 32.05 ? 166 TYR D N   1 
ATOM 3907 C CA  . TYR D 1 166 ? 136.703 200.881 166.149 1.00 29.32 ? 166 TYR D CA  1 
ATOM 3908 C C   . TYR D 1 166 ? 137.366 202.182 165.720 1.00 34.30 ? 166 TYR D C   1 
ATOM 3909 O O   . TYR D 1 166 ? 137.573 202.439 164.533 1.00 41.73 ? 166 TYR D O   1 
ATOM 3910 C CB  . TYR D 1 166 ? 137.105 199.717 165.252 1.00 26.97 ? 166 TYR D CB  1 
ATOM 3911 C CG  . TYR D 1 166 ? 138.542 199.274 165.412 1.00 34.77 ? 166 TYR D CG  1 
ATOM 3912 C CD1 . TYR D 1 166 ? 138.903 198.374 166.405 1.00 32.51 ? 166 TYR D CD1 1 
ATOM 3913 C CD2 . TYR D 1 166 ? 139.537 199.757 164.573 1.00 32.02 ? 166 TYR D CD2 1 
ATOM 3914 C CE1 . TYR D 1 166 ? 140.214 197.964 166.555 1.00 34.92 ? 166 TYR D CE1 1 
ATOM 3915 C CE2 . TYR D 1 166 ? 140.850 199.355 164.718 1.00 31.55 ? 166 TYR D CE2 1 
ATOM 3916 C CZ  . TYR D 1 166 ? 141.183 198.459 165.710 1.00 35.62 ? 166 TYR D CZ  1 
ATOM 3917 O OH  . TYR D 1 166 ? 142.489 198.055 165.858 1.00 38.33 ? 166 TYR D OH  1 
ATOM 3918 N N   . ARG D 1 167 ? 137.706 203.018 166.700 1.00 33.37 ? 167 ARG D N   1 
ATOM 3919 C CA  . ARG D 1 167 ? 138.314 204.327 166.456 1.00 38.24 ? 167 ARG D CA  1 
ATOM 3920 C C   . ARG D 1 167 ? 139.541 204.504 167.344 1.00 40.68 ? 167 ARG D C   1 
ATOM 3921 O O   . ARG D 1 167 ? 139.525 205.293 168.298 1.00 37.52 ? 167 ARG D O   1 
ATOM 3922 C CB  . ARG D 1 167 ? 137.297 205.444 166.697 1.00 30.11 ? 167 ARG D CB  1 
ATOM 3923 C CG  . ARG D 1 167 ? 137.739 206.827 166.239 1.00 30.04 ? 167 ARG D CG  1 
ATOM 3924 C CD  . ARG D 1 167 ? 137.144 207.183 164.894 1.00 39.27 ? 167 ARG D CD  1 
ATOM 3925 N NE  . ARG D 1 167 ? 137.462 208.550 164.496 1.00 36.94 ? 167 ARG D NE  1 
ATOM 3926 C CZ  . ARG D 1 167 ? 136.597 209.554 164.512 1.00 38.27 ? 167 ARG D CZ  1 
ATOM 3927 N NH1 . ARG D 1 167 ? 135.343 209.380 164.899 1.00 41.74 ? 167 ARG D NH1 1 
ATOM 3928 N NH2 . ARG D 1 167 ? 136.998 210.762 164.129 1.00 39.05 ? 167 ARG D NH2 1 
ATOM 3929 N N   . PRO D 1 168 ? 140.626 203.781 167.065 1.00 38.42 ? 168 PRO D N   1 
ATOM 3930 C CA  . PRO D 1 168 ? 141.863 203.999 167.822 1.00 30.85 ? 168 PRO D CA  1 
ATOM 3931 C C   . PRO D 1 168 ? 142.598 205.246 167.357 1.00 33.12 ? 168 PRO D C   1 
ATOM 3932 O O   . PRO D 1 168 ? 142.637 205.564 166.166 1.00 38.90 ? 168 PRO D O   1 
ATOM 3933 C CB  . PRO D 1 168 ? 142.680 202.734 167.537 1.00 30.80 ? 168 PRO D CB  1 
ATOM 3934 C CG  . PRO D 1 168 ? 142.207 202.282 166.217 1.00 31.95 ? 168 PRO D CG  1 
ATOM 3935 C CD  . PRO D 1 168 ? 140.750 202.646 166.133 1.00 31.88 ? 168 PRO D CD  1 
ATOM 3936 N N   . VAL D 1 169 ? 143.183 205.957 168.319 1.00 37.48 ? 169 VAL D N   1 
ATOM 3937 C CA  . VAL D 1 169 ? 143.965 207.158 168.056 1.00 38.75 ? 169 VAL D CA  1 
ATOM 3938 C C   . VAL D 1 169 ? 145.319 207.010 168.736 1.00 42.93 ? 169 VAL D C   1 
ATOM 3939 O O   . VAL D 1 169 ? 145.382 206.740 169.941 1.00 42.92 ? 169 VAL D O   1 
ATOM 3940 C CB  . VAL D 1 169 ? 143.251 208.431 168.548 1.00 30.52 ? 169 VAL D CB  1 
ATOM 3941 C CG1 . VAL D 1 169 ? 144.079 209.662 168.220 1.00 34.99 ? 169 VAL D CG1 1 
ATOM 3942 C CG2 . VAL D 1 169 ? 141.862 208.537 167.935 1.00 31.16 ? 169 VAL D CG2 1 
ATOM 3943 N N   . ASP D 1 170 ? 146.392 207.189 167.967 1.00 34.93 ? 170 ASP D N   1 
ATOM 3944 C CA  . ASP D 1 170 ? 147.762 207.163 168.483 1.00 29.56 ? 170 ASP D CA  1 
ATOM 3945 C C   . ASP D 1 170 ? 148.046 205.870 169.247 1.00 30.61 ? 170 ASP D C   1 
ATOM 3946 O O   . ASP D 1 170 ? 148.596 205.875 170.350 1.00 34.97 ? 170 ASP D O   1 
ATOM 3947 C CB  . ASP D 1 170 ? 148.037 208.385 169.359 1.00 34.32 ? 170 ASP D CB  1 
ATOM 3948 C CG  . ASP D 1 170 ? 147.792 209.692 168.632 1.00 38.06 ? 170 ASP D CG  1 
ATOM 3949 O OD1 . ASP D 1 170 ? 147.449 209.652 167.433 1.00 42.49 ? 170 ASP D OD1 1 
ATOM 3950 O OD2 . ASP D 1 170 ? 147.944 210.761 169.260 1.00 39.16 ? 170 ASP D OD2 1 
ATOM 3951 N N   . GLN D 1 171 ? 147.663 204.748 168.644 1.00 33.72 ? 171 GLN D N   1 
ATOM 3952 C CA  . GLN D 1 171 ? 147.872 203.438 169.253 1.00 34.83 ? 171 GLN D CA  1 
ATOM 3953 C C   . GLN D 1 171 ? 149.293 202.980 168.945 1.00 33.08 ? 171 GLN D C   1 
ATOM 3954 O O   . GLN D 1 171 ? 149.622 202.694 167.790 1.00 30.74 ? 171 GLN D O   1 
ATOM 3955 C CB  . GLN D 1 171 ? 146.838 202.441 168.736 1.00 25.75 ? 171 GLN D CB  1 
ATOM 3956 C CG  . GLN D 1 171 ? 146.453 201.367 169.737 1.00 28.18 ? 171 GLN D CG  1 
ATOM 3957 C CD  . GLN D 1 171 ? 145.386 200.429 169.202 1.00 28.61 ? 171 GLN D CD  1 
ATOM 3958 O OE1 . GLN D 1 171 ? 145.233 200.274 167.991 1.00 34.46 ? 171 GLN D OE1 1 
ATOM 3959 N NE2 . GLN D 1 171 ? 144.643 199.799 170.104 1.00 23.06 ? 171 GLN D NE2 1 
ATOM 3960 N N   . TYR D 1 172 ? 150.137 202.912 169.972 1.00 33.45 ? 172 TYR D N   1 
ATOM 3961 C CA  . TYR D 1 172 ? 151.528 202.476 169.845 1.00 29.28 ? 172 TYR D CA  1 
ATOM 3962 C C   . TYR D 1 172 ? 151.715 201.257 170.741 1.00 35.69 ? 172 TYR D C   1 
ATOM 3963 O O   . TYR D 1 172 ? 152.186 201.370 171.873 1.00 42.15 ? 172 TYR D O   1 
ATOM 3964 C CB  . TYR D 1 172 ? 152.507 203.604 170.219 1.00 34.16 ? 172 TYR D CB  1 
ATOM 3965 C CG  . TYR D 1 172 ? 152.543 204.767 169.251 1.00 33.89 ? 172 TYR D CG  1 
ATOM 3966 C CD1 . TYR D 1 172 ? 151.520 205.704 169.223 1.00 29.80 ? 172 TYR D CD1 1 
ATOM 3967 C CD2 . TYR D 1 172 ? 153.610 204.937 168.381 1.00 35.67 ? 172 TYR D CD2 1 
ATOM 3968 C CE1 . TYR D 1 172 ? 151.552 206.771 168.345 1.00 32.75 ? 172 TYR D CE1 1 
ATOM 3969 C CE2 . TYR D 1 172 ? 153.653 206.001 167.501 1.00 37.83 ? 172 TYR D CE2 1 
ATOM 3970 C CZ  . TYR D 1 172 ? 152.620 206.914 167.486 1.00 40.65 ? 172 TYR D CZ  1 
ATOM 3971 O OH  . TYR D 1 172 ? 152.657 207.976 166.611 1.00 44.24 ? 172 TYR D OH  1 
ATOM 3972 N N   . ASN D 1 173 ? 151.375 200.082 170.221 1.00 27.02 ? 173 ASN D N   1 
ATOM 3973 C CA  . ASN D 1 173 ? 151.432 198.847 170.992 1.00 23.51 ? 173 ASN D CA  1 
ATOM 3974 C C   . ASN D 1 173 ? 152.437 197.891 170.366 1.00 31.96 ? 173 ASN D C   1 
ATOM 3975 O O   . ASN D 1 173 ? 152.577 197.835 169.140 1.00 35.72 ? 173 ASN D O   1 
ATOM 3976 C CB  . ASN D 1 173 ? 150.058 198.180 171.076 1.00 22.96 ? 173 ASN D CB  1 
ATOM 3977 C CG  . ASN D 1 173 ? 149.069 198.985 171.893 1.00 32.44 ? 173 ASN D CG  1 
ATOM 3978 O OD1 . ASN D 1 173 ? 149.455 199.772 172.756 1.00 38.15 ? 173 ASN D OD1 1 
ATOM 3979 N ND2 . ASN D 1 173 ? 147.783 198.790 171.625 1.00 32.79 ? 173 ASN D ND2 1 
ATOM 3980 N N   . ASN D 1 174 ? 153.135 197.141 171.217 1.00 30.72 ? 174 ASN D N   1 
ATOM 3981 C CA  . ASN D 1 174 ? 154.165 196.206 170.782 1.00 20.94 ? 174 ASN D CA  1 
ATOM 3982 C C   . ASN D 1 174 ? 153.920 194.856 171.436 1.00 25.58 ? 174 ASN D C   1 
ATOM 3983 O O   . ASN D 1 174 ? 153.969 194.740 172.665 1.00 36.65 ? 174 ASN D O   1 
ATOM 3984 C CB  . ASN D 1 174 ? 155.562 196.723 171.134 1.00 19.07 ? 174 ASN D CB  1 
ATOM 3985 C CG  . ASN D 1 174 ? 155.988 197.888 170.266 1.00 30.17 ? 174 ASN D CG  1 
ATOM 3986 O OD1 . ASN D 1 174 ? 155.610 199.033 170.514 1.00 38.76 ? 174 ASN D OD1 1 
ATOM 3987 N ND2 . ASN D 1 174 ? 156.783 197.603 169.240 1.00 26.67 ? 174 ASN D ND2 1 
ATOM 3988 N N   . GLN D 1 175 ? 153.657 193.839 170.615 1.00 29.57 ? 175 GLN D N   1 
ATOM 3989 C CA  . GLN D 1 175 ? 153.551 192.450 171.063 1.00 30.86 ? 175 GLN D CA  1 
ATOM 3990 C C   . GLN D 1 175 ? 154.455 191.634 170.144 1.00 29.89 ? 175 GLN D C   1 
ATOM 3991 O O   . GLN D 1 175 ? 153.998 191.066 169.149 1.00 29.59 ? 175 GLN D O   1 
ATOM 3992 C CB  . GLN D 1 175 ? 152.108 191.958 171.030 1.00 22.86 ? 175 GLN D CB  1 
ATOM 3993 C CG  . GLN D 1 175 ? 151.894 190.619 171.714 1.00 24.78 ? 175 GLN D CG  1 
ATOM 3994 C CD  . GLN D 1 175 ? 150.427 190.273 171.874 1.00 26.54 ? 175 GLN D CD  1 
ATOM 3995 O OE1 . GLN D 1 175 ? 149.591 190.677 171.066 1.00 33.43 ? 175 GLN D OE1 1 
ATOM 3996 N NE2 . GLN D 1 175 ? 150.108 189.524 172.921 1.00 27.21 ? 175 GLN D NE2 1 
ATOM 3997 N N   . ASN D 1 176 ? 155.739 191.571 170.485 1.00 26.95 ? 176 ASN D N   1 
ATOM 3998 C CA  . ASN D 1 176 ? 156.748 190.977 169.624 1.00 26.18 ? 176 ASN D CA  1 
ATOM 3999 C C   . ASN D 1 176 ? 157.423 189.805 170.323 1.00 30.01 ? 176 ASN D C   1 
ATOM 4000 O O   . ASN D 1 176 ? 157.604 189.806 171.543 1.00 30.20 ? 176 ASN D O   1 
ATOM 4001 C CB  . ASN D 1 176 ? 157.804 192.011 169.216 1.00 32.05 ? 176 ASN D CB  1 
ATOM 4002 C CG  . ASN D 1 176 ? 157.196 193.247 168.586 1.00 34.20 ? 176 ASN D CG  1 
ATOM 4003 O OD1 . ASN D 1 176 ? 156.243 193.158 167.813 1.00 35.76 ? 176 ASN D OD1 1 
ATOM 4004 N ND2 . ASN D 1 176 ? 157.744 194.410 168.917 1.00 35.64 ? 176 ASN D ND2 1 
ATOM 4005 N N   . THR D 1 177 ? 157.797 188.806 169.530 1.00 40.26 ? 177 THR D N   1 
ATOM 4006 C CA  . THR D 1 177 ? 158.533 187.644 170.010 1.00 36.19 ? 177 THR D CA  1 
ATOM 4007 C C   . THR D 1 177 ? 159.970 187.744 169.517 1.00 30.76 ? 177 THR D C   1 
ATOM 4008 O O   . THR D 1 177 ? 160.211 187.808 168.306 1.00 36.74 ? 177 THR D O   1 
ATOM 4009 C CB  . THR D 1 177 ? 157.890 186.344 169.528 1.00 32.36 ? 177 THR D CB  1 
ATOM 4010 O OG1 . THR D 1 177 ? 156.559 186.244 170.049 1.00 28.76 ? 177 THR D OG1 1 
ATOM 4011 C CG2 . THR D 1 177 ? 158.705 185.149 169.990 1.00 33.83 ? 177 THR D CG2 1 
ATOM 4012 N N   . PHE D 1 178 ? 160.916 187.761 170.451 1.00 28.92 ? 178 PHE D N   1 
ATOM 4013 C CA  . PHE D 1 178 ? 162.335 187.869 170.135 1.00 29.69 ? 178 PHE D CA  1 
ATOM 4014 C C   . PHE D 1 178 ? 163.038 186.601 170.591 1.00 34.55 ? 178 PHE D C   1 
ATOM 4015 O O   . PHE D 1 178 ? 162.970 186.240 171.771 1.00 39.63 ? 178 PHE D O   1 
ATOM 4016 C CB  . PHE D 1 178 ? 162.954 189.099 170.802 1.00 30.28 ? 178 PHE D CB  1 
ATOM 4017 C CG  . PHE D 1 178 ? 162.830 190.356 169.991 1.00 33.96 ? 178 PHE D CG  1 
ATOM 4018 C CD1 . PHE D 1 178 ? 161.700 191.150 170.090 1.00 33.69 ? 178 PHE D CD1 1 
ATOM 4019 C CD2 . PHE D 1 178 ? 163.843 190.743 169.131 1.00 36.35 ? 178 PHE D CD2 1 
ATOM 4020 C CE1 . PHE D 1 178 ? 161.583 192.307 169.343 1.00 35.22 ? 178 PHE D CE1 1 
ATOM 4021 C CE2 . PHE D 1 178 ? 163.732 191.900 168.383 1.00 38.84 ? 178 PHE D CE2 1 
ATOM 4022 C CZ  . PHE D 1 178 ? 162.600 192.683 168.490 1.00 39.11 ? 178 PHE D CZ  1 
ATOM 4023 N N   . VAL D 1 179 ? 163.710 185.930 169.661 1.00 37.15 ? 179 VAL D N   1 
ATOM 4024 C CA  . VAL D 1 179 ? 164.486 184.731 169.953 1.00 30.20 ? 179 VAL D CA  1 
ATOM 4025 C C   . VAL D 1 179 ? 165.901 184.958 169.448 1.00 26.14 ? 179 VAL D C   1 
ATOM 4026 O O   . VAL D 1 179 ? 166.117 185.105 168.239 1.00 34.27 ? 179 VAL D O   1 
ATOM 4027 C CB  . VAL D 1 179 ? 163.876 183.473 169.313 1.00 29.16 ? 179 VAL D CB  1 
ATOM 4028 C CG1 . VAL D 1 179 ? 164.849 182.307 169.403 1.00 29.18 ? 179 VAL D CG1 1 
ATOM 4029 C CG2 . VAL D 1 179 ? 162.563 183.123 169.988 1.00 28.26 ? 179 VAL D CG2 1 
ATOM 4030 N N   . HIS D 1 180 ? 166.861 184.989 170.368 1.00 30.99 ? 180 HIS D N   1 
ATOM 4031 C CA  . HIS D 1 180 ? 168.271 185.161 170.039 1.00 35.83 ? 180 HIS D CA  1 
ATOM 4032 C C   . HIS D 1 180 ? 169.019 183.925 170.520 1.00 34.92 ? 180 HIS D C   1 
ATOM 4033 O O   . HIS D 1 180 ? 169.228 183.750 171.725 1.00 41.11 ? 180 HIS D O   1 
ATOM 4034 C CB  . HIS D 1 180 ? 168.836 186.431 170.673 1.00 37.66 ? 180 HIS D CB  1 
ATOM 4035 C CG  . HIS D 1 180 ? 168.579 187.670 169.874 1.00 37.42 ? 180 HIS D CG  1 
ATOM 4036 N ND1 . HIS D 1 180 ? 169.476 188.714 169.811 1.00 35.05 ? 180 HIS D ND1 1 
ATOM 4037 C CD2 . HIS D 1 180 ? 167.527 188.032 169.103 1.00 38.81 ? 180 HIS D CD2 1 
ATOM 4038 C CE1 . HIS D 1 180 ? 168.987 189.666 169.036 1.00 41.71 ? 180 HIS D CE1 1 
ATOM 4039 N NE2 . HIS D 1 180 ? 167.806 189.276 168.594 1.00 38.77 ? 180 HIS D NE2 1 
ATOM 4040 N N   . ASP D 1 181 ? 169.417 183.072 169.580 1.00 45.73 ? 181 ASP D N   1 
ATOM 4041 C CA  . ASP D 1 181 ? 170.117 181.832 169.886 1.00 45.25 ? 181 ASP D CA  1 
ATOM 4042 C C   . ASP D 1 181 ? 171.486 181.865 169.226 1.00 44.49 ? 181 ASP D C   1 
ATOM 4043 O O   . ASP D 1 181 ? 171.582 181.991 168.000 1.00 43.21 ? 181 ASP D O   1 
ATOM 4044 C CB  . ASP D 1 181 ? 169.318 180.618 169.410 1.00 41.27 ? 181 ASP D CB  1 
ATOM 4045 C CG  . ASP D 1 181 ? 169.854 179.314 169.964 1.00 47.44 ? 181 ASP D CG  1 
ATOM 4046 O OD1 . ASP D 1 181 ? 169.715 179.082 171.183 1.00 50.55 ? 181 ASP D OD1 1 
ATOM 4047 O OD2 . ASP D 1 181 ? 170.417 178.521 169.180 1.00 46.95 ? 181 ASP D OD2 1 
ATOM 4048 N N   . CYS D 1 182 ? 172.536 181.746 170.039 1.00 41.99 ? 182 CYS D N   1 
ATOM 4049 C CA  . CYS D 1 182 ? 173.916 181.695 169.554 1.00 37.09 ? 182 CYS D CA  1 
ATOM 4050 C C   . CYS D 1 182 ? 174.261 182.919 168.709 1.00 39.66 ? 182 CYS D C   1 
ATOM 4051 O O   . CYS D 1 182 ? 174.887 182.813 167.654 1.00 43.22 ? 182 CYS D O   1 
ATOM 4052 C CB  . CYS D 1 182 ? 174.172 180.406 168.773 1.00 40.47 ? 182 CYS D CB  1 
ATOM 4053 S SG  . CYS D 1 182 ? 174.172 178.925 169.799 1.00 63.20 ? 182 CYS D SG  1 
ATOM 4054 N N   . VAL D 1 183 ? 173.852 184.091 169.180 1.00 36.16 ? 183 VAL D N   1 
ATOM 4055 C CA  . VAL D 1 183 ? 174.106 185.347 168.487 1.00 33.28 ? 183 VAL D CA  1 
ATOM 4056 C C   . VAL D 1 183 ? 175.302 186.030 169.132 1.00 24.08 ? 183 VAL D C   1 
ATOM 4057 O O   . VAL D 1 183 ? 175.566 185.870 170.329 1.00 36.03 ? 183 VAL D O   1 
ATOM 4058 C CB  . VAL D 1 183 ? 172.862 186.260 168.508 1.00 33.36 ? 183 VAL D CB  1 
ATOM 4059 C CG1 . VAL D 1 183 ? 173.180 187.614 167.890 1.00 35.78 ? 183 VAL D CG1 1 
ATOM 4060 C CG2 . VAL D 1 183 ? 171.708 185.596 167.778 1.00 30.11 ? 183 VAL D CG2 1 
ATOM 4061 N N   . ASN D 1 184 ? 176.033 186.801 168.325 1.00 27.82 ? 184 ASN D N   1 
ATOM 4062 C CA  . ASN D 1 184 ? 177.203 187.554 168.781 1.00 35.27 ? 184 ASN D CA  1 
ATOM 4063 C C   . ASN D 1 184 ? 178.247 186.638 169.416 1.00 32.20 ? 184 ASN D C   1 
ATOM 4064 O O   . ASN D 1 184 ? 178.841 186.962 170.447 1.00 29.28 ? 184 ASN D O   1 
ATOM 4065 C CB  . ASN D 1 184 ? 176.798 188.671 169.748 1.00 33.08 ? 184 ASN D CB  1 
ATOM 4066 C CG  . ASN D 1 184 ? 175.988 189.761 169.073 1.00 32.32 ? 184 ASN D CG  1 
ATOM 4067 O OD1 . ASN D 1 184 ? 175.441 189.562 167.989 1.00 34.08 ? 184 ASN D OD1 1 
ATOM 4068 N ND2 . ASN D 1 184 ? 175.908 190.921 169.713 1.00 34.73 ? 184 ASN D ND2 1 
ATOM 4069 N N   . ILE D 1 185 ? 178.475 185.485 168.796 1.00 30.52 ? 185 ILE D N   1 
ATOM 4070 C CA  . ILE D 1 185 ? 179.503 184.552 169.240 1.00 30.93 ? 185 ILE D CA  1 
ATOM 4071 C C   . ILE D 1 185 ? 180.807 184.917 168.543 1.00 27.44 ? 185 ILE D C   1 
ATOM 4072 O O   . ILE D 1 185 ? 180.874 184.946 167.309 1.00 31.09 ? 185 ILE D O   1 
ATOM 4073 C CB  . ILE D 1 185 ? 179.105 183.099 168.944 1.00 30.18 ? 185 ILE D CB  1 
ATOM 4074 C CG1 . ILE D 1 185 ? 177.886 182.701 169.776 1.00 30.01 ? 185 ILE D CG1 1 
ATOM 4075 C CG2 . ILE D 1 185 ? 180.275 182.165 169.212 1.00 27.74 ? 185 ILE D CG2 1 
ATOM 4076 C CD1 . ILE D 1 185 ? 177.594 181.217 169.761 1.00 30.44 ? 185 ILE D CD1 1 
ATOM 4077 N N   . THR D 1 186 ? 181.843 185.193 169.329 1.00 27.62 ? 186 THR D N   1 
ATOM 4078 C CA  . THR D 1 186 ? 183.118 185.655 168.797 1.00 33.30 ? 186 THR D CA  1 
ATOM 4079 C C   . THR D 1 186 ? 184.251 184.811 169.360 1.00 30.62 ? 186 THR D C   1 
ATOM 4080 O O   . THR D 1 186 ? 184.364 184.646 170.579 1.00 24.31 ? 186 THR D O   1 
ATOM 4081 C CB  . THR D 1 186 ? 183.353 187.133 169.129 1.00 34.76 ? 186 THR D CB  1 
ATOM 4082 O OG1 . THR D 1 186 ? 182.264 187.915 168.624 1.00 42.10 ? 186 THR D OG1 1 
ATOM 4083 C CG2 . THR D 1 186 ? 184.652 187.620 168.503 1.00 33.05 ? 186 THR D CG2 1 
ATOM 4084 N N   . VAL D 1 187 ? 185.084 184.280 168.468 1.00 28.27 ? 187 VAL D N   1 
ATOM 4085 C CA  . VAL D 1 187 ? 186.328 183.611 168.829 1.00 27.56 ? 187 VAL D CA  1 
ATOM 4086 C C   . VAL D 1 187 ? 187.428 184.356 168.086 1.00 26.51 ? 187 VAL D C   1 
ATOM 4087 O O   . VAL D 1 187 ? 187.656 184.118 166.894 1.00 36.66 ? 187 VAL D O   1 
ATOM 4088 C CB  . VAL D 1 187 ? 186.318 182.120 168.474 1.00 28.93 ? 187 VAL D CB  1 
ATOM 4089 C CG1 . VAL D 1 187 ? 187.540 181.431 169.054 1.00 29.77 ? 187 VAL D CG1 1 
ATOM 4090 C CG2 . VAL D 1 187 ? 185.041 181.461 168.976 1.00 30.31 ? 187 VAL D CG2 1 
ATOM 4091 N N   . LYS D 1 188 ? 188.117 185.258 168.781 1.00 23.75 ? 188 LYS D N   1 
ATOM 4092 C CA  . LYS D 1 188 ? 189.012 186.204 168.134 1.00 29.88 ? 188 LYS D CA  1 
ATOM 4093 C C   . LYS D 1 188 ? 190.325 186.292 168.899 1.00 28.73 ? 188 LYS D C   1 
ATOM 4094 O O   . LYS D 1 188 ? 190.376 186.054 170.106 1.00 41.12 ? 188 LYS D O   1 
ATOM 4095 C CB  . LYS D 1 188 ? 188.364 187.595 168.037 1.00 29.75 ? 188 LYS D CB  1 
ATOM 4096 C CG  . LYS D 1 188 ? 189.088 188.582 167.135 1.00 28.86 ? 188 LYS D CG  1 
ATOM 4097 C CD  . LYS D 1 188 ? 188.477 189.970 167.235 1.00 27.86 ? 188 LYS D CD  1 
ATOM 4098 C CE  . LYS D 1 188 ? 189.222 190.967 166.363 1.00 38.02 ? 188 LYS D CE  1 
ATOM 4099 N NZ  . LYS D 1 188 ? 188.774 192.365 166.606 1.00 31.08 ? 188 LYS D NZ  1 
ATOM 4100 N N   . GLN D 1 189 ? 191.390 186.624 168.173 1.00 38.59 ? 189 GLN D N   1 
ATOM 4101 C CA  . GLN D 1 189 ? 192.680 186.968 168.764 1.00 40.40 ? 189 GLN D CA  1 
ATOM 4102 C C   . GLN D 1 189 ? 193.111 188.304 168.176 1.00 42.87 ? 189 GLN D C   1 
ATOM 4103 O O   . GLN D 1 189 ? 193.435 188.388 166.987 1.00 47.50 ? 189 GLN D O   1 
ATOM 4104 C CB  . GLN D 1 189 ? 193.727 185.884 168.502 1.00 40.37 ? 189 GLN D CB  1 
ATOM 4105 C CG  . GLN D 1 189 ? 193.585 185.176 167.166 1.00 44.91 ? 189 GLN D CG  1 
ATOM 4106 C CD  . GLN D 1 189 ? 194.563 184.029 167.012 1.00 46.36 ? 189 GLN D CD  1 
ATOM 4107 O OE1 . GLN D 1 189 ? 195.387 183.777 167.892 1.00 46.81 ? 189 GLN D OE1 1 
ATOM 4108 N NE2 . GLN D 1 189 ? 194.480 183.325 165.889 1.00 41.98 ? 189 GLN D NE2 1 
ATOM 4109 N N   . HIS D 1 190 ? 193.112 189.346 169.003 1.00 35.85 ? 190 HIS D N   1 
ATOM 4110 C CA  . HIS D 1 190 ? 193.380 190.705 168.556 1.00 37.93 ? 190 HIS D CA  1 
ATOM 4111 C C   . HIS D 1 190 ? 194.622 191.249 169.245 1.00 33.62 ? 190 HIS D C   1 
ATOM 4112 O O   . HIS D 1 190 ? 194.811 191.059 170.451 1.00 42.85 ? 190 HIS D O   1 
ATOM 4113 C CB  . HIS D 1 190 ? 192.183 191.619 168.835 1.00 42.39 ? 190 HIS D CB  1 
ATOM 4114 C CG  . HIS D 1 190 ? 192.371 193.024 168.356 1.00 40.73 ? 190 HIS D CG  1 
ATOM 4115 N ND1 . HIS D 1 190 ? 193.085 193.333 167.218 1.00 44.85 ? 190 HIS D ND1 1 
ATOM 4116 C CD2 . HIS D 1 190 ? 191.934 194.203 168.858 1.00 41.50 ? 190 HIS D CD2 1 
ATOM 4117 C CE1 . HIS D 1 190 ? 193.084 194.642 167.042 1.00 44.48 ? 190 HIS D CE1 1 
ATOM 4118 N NE2 . HIS D 1 190 ? 192.391 195.194 168.022 1.00 42.65 ? 190 HIS D NE2 1 
ATOM 4119 N N   . THR D 1 191 ? 195.468 191.926 168.472 1.00 34.10 ? 191 THR D N   1 
ATOM 4120 C CA  . THR D 1 191 ? 196.697 192.519 168.979 1.00 41.72 ? 191 THR D CA  1 
ATOM 4121 C C   . THR D 1 191 ? 196.793 193.958 168.496 1.00 42.88 ? 191 THR D C   1 
ATOM 4122 O O   . THR D 1 191 ? 196.596 194.230 167.308 1.00 44.24 ? 191 THR D O   1 
ATOM 4123 C CB  . THR D 1 191 ? 197.929 191.730 168.522 1.00 41.33 ? 191 THR D CB  1 
ATOM 4124 O OG1 . THR D 1 191 ? 197.854 190.391 169.021 1.00 42.79 ? 191 THR D OG1 1 
ATOM 4125 C CG2 . THR D 1 191 ? 199.203 192.381 169.040 1.00 39.36 ? 191 THR D CG2 1 
ATOM 4126 N N   . VAL D 1 192 ? 197.095 194.872 169.414 1.00 40.34 ? 192 VAL D N   1 
ATOM 4127 C CA  . VAL D 1 192 ? 197.298 196.279 169.096 1.00 37.48 ? 192 VAL D CA  1 
ATOM 4128 C C   . VAL D 1 192 ? 198.732 196.634 169.459 1.00 39.45 ? 192 VAL D C   1 
ATOM 4129 O O   . VAL D 1 192 ? 199.153 196.439 170.606 1.00 46.10 ? 192 VAL D O   1 
ATOM 4130 C CB  . VAL D 1 192 ? 196.304 197.185 169.839 1.00 41.29 ? 192 VAL D CB  1 
ATOM 4131 C CG1 . VAL D 1 192 ? 196.490 198.633 169.414 1.00 45.82 ? 192 VAL D CG1 1 
ATOM 4132 C CG2 . VAL D 1 192 ? 194.878 196.727 169.585 1.00 39.03 ? 192 VAL D CG2 1 
ATOM 4133 N N   . THR D 1 193 ? 199.478 197.151 168.487 1.00 48.16 ? 193 THR D N   1 
ATOM 4134 C CA  . THR D 1 193 ? 200.867 197.542 168.682 1.00 50.71 ? 193 THR D CA  1 
ATOM 4135 C C   . THR D 1 193 ? 201.011 199.032 168.414 1.00 49.11 ? 193 THR D C   1 
ATOM 4136 O O   . THR D 1 193 ? 200.637 199.514 167.339 1.00 49.10 ? 193 THR D O   1 
ATOM 4137 C CB  . THR D 1 193 ? 201.803 196.749 167.764 1.00 52.40 ? 193 THR D CB  1 
ATOM 4138 O OG1 . THR D 1 193 ? 201.621 195.346 167.989 1.00 48.44 ? 193 THR D OG1 1 
ATOM 4139 C CG2 . THR D 1 193 ? 203.254 197.119 168.037 1.00 51.56 ? 193 THR D CG2 1 
ATOM 4140 N N   . THR D 1 194 ? 201.555 199.758 169.392 1.00 46.47 ? 194 THR D N   1 
ATOM 4141 C CA  . THR D 1 194 ? 201.803 201.197 169.270 1.00 49.09 ? 194 THR D CA  1 
ATOM 4142 C C   . THR D 1 194 ? 203.167 201.474 169.901 1.00 50.70 ? 194 THR D C   1 
ATOM 4143 O O   . THR D 1 194 ? 203.267 201.717 171.107 1.00 52.14 ? 194 THR D O   1 
ATOM 4144 C CB  . THR D 1 194 ? 200.699 202.015 169.927 1.00 49.30 ? 194 THR D CB  1 
ATOM 4145 O OG1 . THR D 1 194 ? 199.423 201.570 169.450 1.00 46.94 ? 194 THR D OG1 1 
ATOM 4146 C CG2 . THR D 1 194 ? 200.867 203.492 169.601 1.00 47.45 ? 194 THR D CG2 1 
ATOM 4147 N N   . THR D 1 195 ? 204.210 201.435 169.080 1.00 49.04 ? 195 THR D N   1 
ATOM 4148 C CA  . THR D 1 195 ? 205.578 201.650 169.529 1.00 53.61 ? 195 THR D CA  1 
ATOM 4149 C C   . THR D 1 195 ? 206.111 202.946 168.934 1.00 52.35 ? 195 THR D C   1 
ATOM 4150 O O   . THR D 1 195 ? 206.023 203.159 167.720 1.00 49.17 ? 195 THR D O   1 
ATOM 4151 C CB  . THR D 1 195 ? 206.479 200.479 169.132 1.00 50.40 ? 195 THR D CB  1 
ATOM 4152 O OG1 . THR D 1 195 ? 205.943 199.260 169.661 1.00 52.03 ? 195 THR D OG1 1 
ATOM 4153 C CG2 . THR D 1 195 ? 207.885 200.684 169.676 1.00 51.02 ? 195 THR D CG2 1 
ATOM 4154 N N   . THR D 1 196 ? 206.658 203.803 169.789 1.00 53.59 ? 196 THR D N   1 
ATOM 4155 C CA  . THR D 1 196 ? 207.229 205.078 169.377 1.00 52.66 ? 196 THR D CA  1 
ATOM 4156 C C   . THR D 1 196 ? 208.728 205.097 169.637 1.00 54.50 ? 196 THR D C   1 
ATOM 4157 O O   . THR D 1 196 ? 209.163 204.879 170.773 1.00 53.08 ? 196 THR D O   1 
ATOM 4158 C CB  . THR D 1 196 ? 206.579 206.242 170.129 1.00 55.14 ? 196 THR D CB  1 
ATOM 4159 O OG1 . THR D 1 196 ? 205.152 206.130 170.044 1.00 54.11 ? 196 THR D OG1 1 
ATOM 4160 C CG2 . THR D 1 196 ? 207.014 207.571 169.530 1.00 55.02 ? 196 THR D CG2 1 
ATOM 4161 N N   . LYS D 1 197 ? 209.500 205.366 168.582 1.00 65.56 ? 197 LYS D N   1 
ATOM 4162 C CA  . LYS D 1 197 ? 210.967 205.431 168.609 1.00 65.81 ? 197 LYS D CA  1 
ATOM 4163 C C   . LYS D 1 197 ? 211.565 204.289 169.431 1.00 65.64 ? 197 LYS D C   1 
ATOM 4164 O O   . LYS D 1 197 ? 212.427 204.482 170.291 1.00 64.86 ? 197 LYS D O   1 
ATOM 4165 C CB  . LYS D 1 197 ? 211.479 206.795 169.092 1.00 64.87 ? 197 LYS D CB  1 
ATOM 4166 C CG  . LYS D 1 197 ? 210.977 207.271 170.450 1.00 62.96 ? 197 LYS D CG  1 
ATOM 4167 C CD  . LYS D 1 197 ? 211.601 208.603 170.830 1.00 64.76 ? 197 LYS D CD  1 
ATOM 4168 C CE  . LYS D 1 197 ? 211.039 209.738 169.988 1.00 65.57 ? 197 LYS D CE  1 
ATOM 4169 N NZ  . LYS D 1 197 ? 209.568 209.888 170.164 1.00 63.84 ? 197 LYS D NZ  1 
ATOM 4170 N N   . GLY D 1 198 ? 211.098 203.076 169.146 1.00 60.50 ? 198 GLY D N   1 
ATOM 4171 C CA  . GLY D 1 198 ? 211.651 201.890 169.773 1.00 59.33 ? 198 GLY D CA  1 
ATOM 4172 C C   . GLY D 1 198 ? 212.952 201.467 169.125 1.00 59.91 ? 198 GLY D C   1 
ATOM 4173 O O   . GLY D 1 198 ? 212.971 201.089 167.950 1.00 61.04 ? 198 GLY D O   1 
ATOM 4174 N N   . GLU D 1 199 ? 214.047 201.525 169.877 1.00 58.39 ? 199 GLU D N   1 
ATOM 4175 C CA  . GLU D 1 199 ? 215.380 201.275 169.347 1.00 60.87 ? 199 GLU D CA  1 
ATOM 4176 C C   . GLU D 1 199 ? 215.955 199.999 169.947 1.00 60.52 ? 199 GLU D C   1 
ATOM 4177 O O   . GLU D 1 199 ? 215.973 199.837 171.172 1.00 59.17 ? 199 GLU D O   1 
ATOM 4178 C CB  . GLU D 1 199 ? 216.309 202.457 169.636 1.00 62.13 ? 199 GLU D CB  1 
ATOM 4179 C CG  . GLU D 1 199 ? 215.909 203.745 168.937 1.00 63.39 ? 199 GLU D CG  1 
ATOM 4180 C CD  . GLU D 1 199 ? 216.725 204.937 169.399 1.00 64.46 ? 199 GLU D CD  1 
ATOM 4181 O OE1 . GLU D 1 199 ? 217.238 204.902 170.536 1.00 61.74 ? 199 GLU D OE1 1 
ATOM 4182 O OE2 . GLU D 1 199 ? 216.853 205.907 168.623 1.00 64.33 ? 199 GLU D OE2 1 
ATOM 4183 N N   . ASN D 1 200 ? 216.425 199.103 169.076 1.00 68.57 ? 200 ASN D N   1 
ATOM 4184 C CA  . ASN D 1 200 ? 217.138 197.888 169.479 1.00 68.12 ? 200 ASN D CA  1 
ATOM 4185 C C   . ASN D 1 200 ? 216.313 197.033 170.437 1.00 63.31 ? 200 ASN D C   1 
ATOM 4186 O O   . ASN D 1 200 ? 216.836 196.470 171.400 1.00 63.03 ? 200 ASN D O   1 
ATOM 4187 C CB  . ASN D 1 200 ? 218.497 198.228 170.093 1.00 65.91 ? 200 ASN D CB  1 
ATOM 4188 C CG  . ASN D 1 200 ? 219.350 199.089 169.182 1.00 68.81 ? 200 ASN D CG  1 
ATOM 4189 O OD1 . ASN D 1 200 ? 219.338 200.316 169.277 1.00 69.14 ? 200 ASN D OD1 1 
ATOM 4190 N ND2 . ASN D 1 200 ? 220.096 198.447 168.290 1.00 67.93 ? 200 ASN D ND2 1 
ATOM 4191 N N   . PHE D 1 201 ? 215.015 196.920 170.169 1.00 51.68 ? 201 PHE D N   1 
ATOM 4192 C CA  . PHE D 1 201 ? 214.120 196.151 171.018 1.00 54.38 ? 201 PHE D CA  1 
ATOM 4193 C C   . PHE D 1 201 ? 213.484 195.015 170.226 1.00 52.48 ? 201 PHE D C   1 
ATOM 4194 O O   . PHE D 1 201 ? 213.257 195.126 169.018 1.00 53.11 ? 201 PHE D O   1 
ATOM 4195 C CB  . PHE D 1 201 ? 213.037 197.048 171.646 1.00 55.05 ? 201 PHE D CB  1 
ATOM 4196 C CG  . PHE D 1 201 ? 211.789 197.191 170.817 1.00 56.16 ? 201 PHE D CG  1 
ATOM 4197 C CD1 . PHE D 1 201 ? 211.676 198.206 169.883 1.00 52.21 ? 201 PHE D CD1 1 
ATOM 4198 C CD2 . PHE D 1 201 ? 210.713 196.331 170.997 1.00 54.54 ? 201 PHE D CD2 1 
ATOM 4199 C CE1 . PHE D 1 201 ? 210.527 198.348 169.129 1.00 50.84 ? 201 PHE D CE1 1 
ATOM 4200 C CE2 . PHE D 1 201 ? 209.565 196.468 170.242 1.00 51.94 ? 201 PHE D CE2 1 
ATOM 4201 C CZ  . PHE D 1 201 ? 209.471 197.478 169.308 1.00 52.23 ? 201 PHE D CZ  1 
ATOM 4202 N N   . THR D 1 202 ? 213.203 193.919 170.923 1.00 52.32 ? 202 THR D N   1 
ATOM 4203 C CA  . THR D 1 202 ? 212.601 192.732 170.332 1.00 53.03 ? 202 THR D CA  1 
ATOM 4204 C C   . THR D 1 202 ? 211.167 192.595 170.821 1.00 50.78 ? 202 THR D C   1 
ATOM 4205 O O   . THR D 1 202 ? 210.910 192.646 172.028 1.00 53.86 ? 202 THR D O   1 
ATOM 4206 C CB  . THR D 1 202 ? 213.401 191.476 170.685 1.00 50.28 ? 202 THR D CB  1 
ATOM 4207 O OG1 . THR D 1 202 ? 214.743 191.609 170.198 1.00 53.98 ? 202 THR D OG1 1 
ATOM 4208 C CG2 . THR D 1 202 ? 212.763 190.244 170.063 1.00 50.97 ? 202 THR D CG2 1 
ATOM 4209 N N   . GLU D 1 203 ? 210.240 192.424 169.884 1.00 51.17 ? 203 GLU D N   1 
ATOM 4210 C CA  . GLU D 1 203 ? 208.825 192.260 170.188 1.00 48.56 ? 203 GLU D CA  1 
ATOM 4211 C C   . GLU D 1 203 ? 208.385 190.854 169.810 1.00 50.88 ? 203 GLU D C   1 
ATOM 4212 O O   . GLU D 1 203 ? 208.581 190.425 168.668 1.00 53.33 ? 203 GLU D O   1 
ATOM 4213 C CB  . GLU D 1 203 ? 207.983 193.297 169.442 1.00 52.89 ? 203 GLU D CB  1 
ATOM 4214 C CG  . GLU D 1 203 ? 206.501 193.236 169.766 1.00 56.11 ? 203 GLU D CG  1 
ATOM 4215 C CD  . GLU D 1 203 ? 205.704 194.306 169.047 1.00 55.62 ? 203 GLU D CD  1 
ATOM 4216 O OE1 . GLU D 1 203 ? 206.304 195.073 168.267 1.00 53.41 ? 203 GLU D OE1 1 
ATOM 4217 O OE2 . GLU D 1 203 ? 204.476 194.376 169.264 1.00 55.09 ? 203 GLU D OE2 1 
ATOM 4218 N N   . THR D 1 204 ? 207.796 190.142 170.766 1.00 52.68 ? 204 THR D N   1 
ATOM 4219 C CA  . THR D 1 204 ? 207.302 188.789 170.545 1.00 54.63 ? 204 THR D CA  1 
ATOM 4220 C C   . THR D 1 204 ? 205.837 188.721 170.950 1.00 51.93 ? 204 THR D C   1 
ATOM 4221 O O   . THR D 1 204 ? 205.494 189.017 172.099 1.00 57.57 ? 204 THR D O   1 
ATOM 4222 C CB  . THR D 1 204 ? 208.117 187.761 171.337 1.00 53.25 ? 204 THR D CB  1 
ATOM 4223 O OG1 . THR D 1 204 ? 209.495 187.843 170.953 1.00 55.87 ? 204 THR D OG1 1 
ATOM 4224 C CG2 . THR D 1 204 ? 207.605 186.355 171.067 1.00 52.63 ? 204 THR D CG2 1 
ATOM 4225 N N   . ASP D 1 205 ? 204.984 188.315 170.012 1.00 44.95 ? 205 ASP D N   1 
ATOM 4226 C CA  . ASP D 1 205 ? 203.543 188.208 170.231 1.00 45.63 ? 205 ASP D CA  1 
ATOM 4227 C C   . ASP D 1 205 ? 203.089 186.845 169.719 1.00 48.71 ? 205 ASP D C   1 
ATOM 4228 O O   . ASP D 1 205 ? 202.861 186.670 168.518 1.00 55.01 ? 205 ASP D O   1 
ATOM 4229 C CB  . ASP D 1 205 ? 202.789 189.337 169.531 1.00 51.54 ? 205 ASP D CB  1 
ATOM 4230 C CG  . ASP D 1 205 ? 203.001 190.685 170.195 1.00 56.86 ? 205 ASP D CG  1 
ATOM 4231 O OD1 . ASP D 1 205 ? 203.487 190.719 171.343 1.00 54.93 ? 205 ASP D OD1 1 
ATOM 4232 O OD2 . ASP D 1 205 ? 202.680 191.714 169.564 1.00 56.78 ? 205 ASP D OD2 1 
ATOM 4233 N N   . ILE D 1 206 ? 202.959 185.882 170.627 1.00 41.34 ? 206 ILE D N   1 
ATOM 4234 C CA  . ILE D 1 206 ? 202.519 184.532 170.297 1.00 44.19 ? 206 ILE D CA  1 
ATOM 4235 C C   . ILE D 1 206 ? 201.172 184.293 170.962 1.00 39.49 ? 206 ILE D C   1 
ATOM 4236 O O   . ILE D 1 206 ? 201.033 184.464 172.179 1.00 43.70 ? 206 ILE D O   1 
ATOM 4237 C CB  . ILE D 1 206 ? 203.546 183.477 170.743 1.00 37.28 ? 206 ILE D CB  1 
ATOM 4238 C CG1 . ILE D 1 206 ? 204.920 183.781 170.143 1.00 41.77 ? 206 ILE D CG1 1 
ATOM 4239 C CG2 . ILE D 1 206 ? 203.085 182.085 170.338 1.00 33.21 ? 206 ILE D CG2 1 
ATOM 4240 C CD1 . ILE D 1 206 ? 205.991 182.793 170.545 1.00 42.50 ? 206 ILE D CD1 1 
ATOM 4241 N N   . LYS D 1 207 ? 200.181 183.902 170.162 1.00 36.66 ? 207 LYS D N   1 
ATOM 4242 C CA  . LYS D 1 207 ? 198.836 183.595 170.650 1.00 35.07 ? 207 LYS D CA  1 
ATOM 4243 C C   . LYS D 1 207 ? 198.451 182.232 170.083 1.00 37.98 ? 207 LYS D C   1 
ATOM 4244 O O   . LYS D 1 207 ? 197.861 182.141 169.002 1.00 43.11 ? 207 LYS D O   1 
ATOM 4245 C CB  . LYS D 1 207 ? 197.844 184.684 170.255 1.00 40.96 ? 207 LYS D CB  1 
ATOM 4246 C CG  . LYS D 1 207 ? 198.093 186.016 170.936 1.00 41.93 ? 207 LYS D CG  1 
ATOM 4247 C CD  . LYS D 1 207 ? 197.021 187.029 170.581 1.00 39.80 ? 207 LYS D CD  1 
ATOM 4248 C CE  . LYS D 1 207 ? 197.213 188.316 171.363 1.00 40.21 ? 207 LYS D CE  1 
ATOM 4249 N NZ  . LYS D 1 207 ? 198.405 189.074 170.892 1.00 41.69 ? 207 LYS D NZ  1 
ATOM 4250 N N   . MET D 1 208 ? 198.790 181.175 170.814 1.00 49.38 ? 208 MET D N   1 
ATOM 4251 C CA  . MET D 1 208 ? 198.393 179.833 170.413 1.00 46.82 ? 208 MET D CA  1 
ATOM 4252 C C   . MET D 1 208 ? 196.896 179.649 170.620 1.00 42.45 ? 208 MET D C   1 
ATOM 4253 O O   . MET D 1 208 ? 196.338 180.068 171.637 1.00 51.23 ? 208 MET D O   1 
ATOM 4254 C CB  . MET D 1 208 ? 199.156 178.787 171.226 1.00 47.70 ? 208 MET D CB  1 
ATOM 4255 C CG  . MET D 1 208 ? 200.648 178.745 170.945 1.00 51.54 ? 208 MET D CG  1 
ATOM 4256 S SD  . MET D 1 208 ? 201.507 177.555 171.993 1.00 68.67 ? 208 MET D SD  1 
ATOM 4257 C CE  . MET D 1 208 ? 203.202 177.796 171.461 1.00 54.38 ? 208 MET D CE  1 
ATOM 4258 N N   . MET D 1 209 ? 196.241 179.026 169.642 1.00 44.54 ? 209 MET D N   1 
ATOM 4259 C CA  . MET D 1 209 ? 194.794 178.799 169.674 1.00 45.03 ? 209 MET D CA  1 
ATOM 4260 C C   . MET D 1 209 ? 194.544 177.408 169.092 1.00 51.23 ? 209 MET D C   1 
ATOM 4261 O O   . MET D 1 209 ? 194.405 177.251 167.877 1.00 56.05 ? 209 MET D O   1 
ATOM 4262 C CB  . MET D 1 209 ? 194.068 179.889 168.892 1.00 52.34 ? 209 MET D CB  1 
ATOM 4263 C CG  . MET D 1 209 ? 192.645 180.165 169.334 1.00 52.52 ? 209 MET D CG  1 
ATOM 4264 S SD  . MET D 1 209 ? 192.558 181.270 170.756 1.00 58.69 ? 209 MET D SD  1 
ATOM 4265 C CE  . MET D 1 209 ? 190.805 181.633 170.801 1.00 43.13 ? 209 MET D CE  1 
ATOM 4266 N N   . GLU D 1 210 ? 194.489 176.404 169.965 1.00 47.20 ? 210 GLU D N   1 
ATOM 4267 C CA  . GLU D 1 210 ? 194.349 175.016 169.545 1.00 50.27 ? 210 GLU D CA  1 
ATOM 4268 C C   . GLU D 1 210 ? 193.225 174.349 170.322 1.00 43.23 ? 210 GLU D C   1 
ATOM 4269 O O   . GLU D 1 210 ? 193.182 174.437 171.552 1.00 42.12 ? 210 GLU D O   1 
ATOM 4270 C CB  . GLU D 1 210 ? 195.656 174.242 169.744 1.00 48.50 ? 210 GLU D CB  1 
ATOM 4271 C CG  . GLU D 1 210 ? 196.688 174.484 168.659 1.00 51.76 ? 210 GLU D CG  1 
ATOM 4272 C CD  . GLU D 1 210 ? 197.555 173.268 168.404 1.00 53.42 ? 210 GLU D CD  1 
ATOM 4273 O OE1 . GLU D 1 210 ? 197.652 172.408 169.304 1.00 55.46 ? 210 GLU D OE1 1 
ATOM 4274 O OE2 . GLU D 1 210 ? 198.133 173.170 167.301 1.00 50.29 ? 210 GLU D OE2 1 
ATOM 4275 N N   . ARG D 1 211 ? 192.321 173.684 169.598 1.00 45.35 ? 211 ARG D N   1 
ATOM 4276 C CA  . ARG D 1 211 ? 191.226 172.920 170.199 1.00 46.47 ? 211 ARG D CA  1 
ATOM 4277 C C   . ARG D 1 211 ? 190.420 173.786 171.165 1.00 46.82 ? 211 ARG D C   1 
ATOM 4278 O O   . ARG D 1 211 ? 189.961 173.329 172.213 1.00 46.12 ? 211 ARG D O   1 
ATOM 4279 C CB  . ARG D 1 211 ? 191.759 171.666 170.893 1.00 47.45 ? 211 ARG D CB  1 
ATOM 4280 C CG  . ARG D 1 211 ? 190.859 170.441 170.793 1.00 45.59 ? 211 ARG D CG  1 
ATOM 4281 C CD  . ARG D 1 211 ? 191.563 169.214 171.356 1.00 45.05 ? 211 ARG D CD  1 
ATOM 4282 N NE  . ARG D 1 211 ? 190.651 168.332 172.073 1.00 48.98 ? 211 ARG D NE  1 
ATOM 4283 C CZ  . ARG D 1 211 ? 191.034 167.303 172.813 1.00 50.76 ? 211 ARG D CZ  1 
ATOM 4284 N NH1 . ARG D 1 211 ? 192.312 166.994 172.960 1.00 49.50 ? 211 ARG D NH1 1 
ATOM 4285 N NH2 . ARG D 1 211 ? 190.112 166.566 173.428 1.00 47.89 ? 211 ARG D NH2 1 
ATOM 4286 N N   . VAL D 1 212 ? 190.235 175.054 170.793 1.00 48.66 ? 212 VAL D N   1 
ATOM 4287 C CA  . VAL D 1 212 ? 189.671 176.042 171.710 1.00 45.24 ? 212 VAL D CA  1 
ATOM 4288 C C   . VAL D 1 212 ? 188.169 175.850 171.878 1.00 46.06 ? 212 VAL D C   1 
ATOM 4289 O O   . VAL D 1 212 ? 187.648 175.929 172.994 1.00 51.41 ? 212 VAL D O   1 
ATOM 4290 C CB  . VAL D 1 212 ? 190.016 177.463 171.234 1.00 45.29 ? 212 VAL D CB  1 
ATOM 4291 C CG1 . VAL D 1 212 ? 189.202 178.493 171.998 1.00 45.67 ? 212 VAL D CG1 1 
ATOM 4292 C CG2 . VAL D 1 212 ? 191.490 177.718 171.433 1.00 47.61 ? 212 VAL D CG2 1 
ATOM 4293 N N   . VAL D 1 213 ? 187.444 175.657 170.779 1.00 40.84 ? 213 VAL D N   1 
ATOM 4294 C CA  . VAL D 1 213 ? 186.030 175.294 170.813 1.00 41.21 ? 213 VAL D CA  1 
ATOM 4295 C C   . VAL D 1 213 ? 185.867 174.065 169.931 1.00 47.58 ? 213 VAL D C   1 
ATOM 4296 O O   . VAL D 1 213 ? 186.090 174.132 168.717 1.00 48.73 ? 213 VAL D O   1 
ATOM 4297 C CB  . VAL D 1 213 ? 185.123 176.445 170.346 1.00 44.20 ? 213 VAL D CB  1 
ATOM 4298 C CG1 . VAL D 1 213 ? 183.662 176.098 170.581 1.00 41.51 ? 213 VAL D CG1 1 
ATOM 4299 C CG2 . VAL D 1 213 ? 185.484 177.740 171.061 1.00 44.98 ? 213 VAL D CG2 1 
ATOM 4300 N N   . GLU D 1 214 ? 185.433 172.954 170.521 1.00 49.20 ? 214 GLU D N   1 
ATOM 4301 C CA  . GLU D 1 214 ? 185.244 171.746 169.726 1.00 43.81 ? 214 GLU D CA  1 
ATOM 4302 C C   . GLU D 1 214 ? 183.830 171.658 169.174 1.00 42.04 ? 214 GLU D C   1 
ATOM 4303 O O   . GLU D 1 214 ? 183.647 171.289 168.011 1.00 48.73 ? 214 GLU D O   1 
ATOM 4304 C CB  . GLU D 1 214 ? 185.573 170.494 170.547 1.00 47.54 ? 214 GLU D CB  1 
ATOM 4305 C CG  . GLU D 1 214 ? 187.055 170.180 170.664 1.00 44.93 ? 214 GLU D CG  1 
ATOM 4306 C CD  . GLU D 1 214 ? 187.312 168.885 171.407 1.00 49.26 ? 214 GLU D CD  1 
ATOM 4307 O OE1 . GLU D 1 214 ? 186.458 168.491 172.231 1.00 50.88 ? 214 GLU D OE1 1 
ATOM 4308 O OE2 . GLU D 1 214 ? 188.368 168.259 171.177 1.00 51.10 ? 214 GLU D OE2 1 
ATOM 4309 N N   . GLN D 1 215 ? 182.825 171.990 169.980 1.00 37.13 ? 215 GLN D N   1 
ATOM 4310 C CA  . GLN D 1 215 ? 181.442 172.006 169.533 1.00 36.66 ? 215 GLN D CA  1 
ATOM 4311 C C   . GLN D 1 215 ? 180.728 173.207 170.131 1.00 42.88 ? 215 GLN D C   1 
ATOM 4312 O O   . GLN D 1 215 ? 181.066 173.666 171.224 1.00 43.51 ? 215 GLN D O   1 
ATOM 4313 C CB  . GLN D 1 215 ? 180.722 170.709 169.928 1.00 40.01 ? 215 GLN D CB  1 
ATOM 4314 C CG  . GLN D 1 215 ? 181.017 169.538 169.011 1.00 38.49 ? 215 GLN D CG  1 
ATOM 4315 C CD  . GLN D 1 215 ? 182.291 168.810 169.388 1.00 43.54 ? 215 GLN D CD  1 
ATOM 4316 O OE1 . GLN D 1 215 ? 182.625 168.684 170.566 1.00 44.42 ? 215 GLN D OE1 1 
ATOM 4317 N NE2 . GLN D 1 215 ? 183.020 168.345 168.384 1.00 37.51 ? 215 GLN D NE2 1 
ATOM 4318 N N   . MET D 1 216 ? 179.733 173.708 169.403 1.00 48.32 ? 216 MET D N   1 
ATOM 4319 C CA  . MET D 1 216 ? 178.945 174.842 169.865 1.00 43.39 ? 216 MET D CA  1 
ATOM 4320 C C   . MET D 1 216 ? 177.621 174.842 169.116 1.00 40.31 ? 216 MET D C   1 
ATOM 4321 O O   . MET D 1 216 ? 177.597 174.647 167.900 1.00 42.89 ? 216 MET D O   1 
ATOM 4322 C CB  . MET D 1 216 ? 179.694 176.165 169.666 1.00 41.54 ? 216 MET D CB  1 
ATOM 4323 C CG  . MET D 1 216 ? 179.082 177.342 170.408 1.00 44.60 ? 216 MET D CG  1 
ATOM 4324 S SD  . MET D 1 216 ? 180.220 178.725 170.619 1.00 53.13 ? 216 MET D SD  1 
ATOM 4325 C CE  . MET D 1 216 ? 181.241 178.563 169.157 1.00 49.74 ? 216 MET D CE  1 
ATOM 4326 N N   . CYS D 1 217 ? 176.531 175.066 169.853 1.00 43.52 ? 217 CYS D N   1 
ATOM 4327 C CA  . CYS D 1 217 ? 175.183 175.133 169.281 1.00 39.89 ? 217 CYS D CA  1 
ATOM 4328 C C   . CYS D 1 217 ? 174.837 173.879 168.484 1.00 39.07 ? 217 CYS D C   1 
ATOM 4329 O O   . CYS D 1 217 ? 174.229 173.949 167.413 1.00 39.65 ? 217 CYS D O   1 
ATOM 4330 C CB  . CYS D 1 217 ? 175.025 176.383 168.414 1.00 39.68 ? 217 CYS D CB  1 
ATOM 4331 S SG  . CYS D 1 217 ? 175.762 177.867 169.120 1.00 56.99 ? 217 CYS D SG  1 
ATOM 4332 N N   . ILE D 1 218 ? 175.218 172.718 169.012 1.00 39.60 ? 218 ILE D N   1 
ATOM 4333 C CA  . ILE D 1 218 ? 174.955 171.440 168.349 1.00 40.89 ? 218 ILE D CA  1 
ATOM 4334 C C   . ILE D 1 218 ? 173.575 170.986 168.816 1.00 37.93 ? 218 ILE D C   1 
ATOM 4335 O O   . ILE D 1 218 ? 173.421 170.355 169.863 1.00 43.77 ? 218 ILE D O   1 
ATOM 4336 C CB  . ILE D 1 218 ? 176.038 170.406 168.642 1.00 38.54 ? 218 ILE D CB  1 
ATOM 4337 C CG1 . ILE D 1 218 ? 177.426 170.994 168.385 1.00 40.26 ? 218 ILE D CG1 1 
ATOM 4338 C CG2 . ILE D 1 218 ? 175.820 169.158 167.803 1.00 33.45 ? 218 ILE D CG2 1 
ATOM 4339 C CD1 . ILE D 1 218 ? 177.599 171.592 167.016 1.00 36.50 ? 218 ILE D CD1 1 
ATOM 4340 N N   . THR D 1 219 ? 172.557 171.315 168.025 1.00 27.02 ? 219 THR D N   1 
ATOM 4341 C CA  . THR D 1 219 ? 171.188 170.876 168.294 1.00 30.50 ? 219 THR D CA  1 
ATOM 4342 C C   . THR D 1 219 ? 170.989 169.546 167.580 1.00 34.48 ? 219 THR D C   1 
ATOM 4343 O O   . THR D 1 219 ? 170.514 169.486 166.446 1.00 35.24 ? 219 THR D O   1 
ATOM 4344 C CB  . THR D 1 219 ? 170.179 171.922 167.834 1.00 33.52 ? 219 THR D CB  1 
ATOM 4345 O OG1 . THR D 1 219 ? 170.551 173.206 168.351 1.00 36.53 ? 219 THR D OG1 1 
ATOM 4346 C CG2 . THR D 1 219 ? 168.786 171.568 168.332 1.00 32.51 ? 219 THR D CG2 1 
ATOM 4347 N N   . GLN D 1 220 ? 171.364 168.464 168.256 1.00 27.57 ? 220 GLN D N   1 
ATOM 4348 C CA  . GLN D 1 220 ? 171.343 167.128 167.680 1.00 24.68 ? 220 GLN D CA  1 
ATOM 4349 C C   . GLN D 1 220 ? 170.318 166.267 168.404 1.00 19.70 ? 220 GLN D C   1 
ATOM 4350 O O   . GLN D 1 220 ? 170.358 166.149 169.633 1.00 31.43 ? 220 GLN D O   1 
ATOM 4351 C CB  . GLN D 1 220 ? 172.727 166.479 167.760 1.00 26.51 ? 220 GLN D CB  1 
ATOM 4352 C CG  . GLN D 1 220 ? 172.937 165.339 166.782 1.00 31.04 ? 220 GLN D CG  1 
ATOM 4353 C CD  . GLN D 1 220 ? 174.403 165.024 166.563 1.00 32.04 ? 220 GLN D CD  1 
ATOM 4354 O OE1 . GLN D 1 220 ? 175.101 164.602 167.484 1.00 34.98 ? 220 GLN D OE1 1 
ATOM 4355 N NE2 . GLN D 1 220 ? 174.875 165.227 165.340 1.00 27.30 ? 220 GLN D NE2 1 
ATOM 4356 N N   . TYR D 1 221 ? 169.405 165.671 167.644 1.00 18.91 ? 221 TYR D N   1 
ATOM 4357 C CA  . TYR D 1 221 ? 168.426 164.731 168.175 1.00 26.03 ? 221 TYR D CA  1 
ATOM 4358 C C   . TYR D 1 221 ? 168.841 163.330 167.750 1.00 28.67 ? 221 TYR D C   1 
ATOM 4359 O O   . TYR D 1 221 ? 168.987 163.059 166.553 1.00 27.26 ? 221 TYR D O   1 
ATOM 4360 C CB  . TYR D 1 221 ? 167.014 165.053 167.682 1.00 31.08 ? 221 TYR D CB  1 
ATOM 4361 C CG  . TYR D 1 221 ? 166.546 166.460 167.989 1.00 34.35 ? 221 TYR D CG  1 
ATOM 4362 C CD1 . TYR D 1 221 ? 167.138 167.212 168.996 1.00 32.87 ? 221 TYR D CD1 1 
ATOM 4363 C CD2 . TYR D 1 221 ? 165.505 167.033 167.272 1.00 32.90 ? 221 TYR D CD2 1 
ATOM 4364 C CE1 . TYR D 1 221 ? 166.714 168.496 169.274 1.00 32.11 ? 221 TYR D CE1 1 
ATOM 4365 C CE2 . TYR D 1 221 ? 165.071 168.317 167.545 1.00 31.97 ? 221 TYR D CE2 1 
ATOM 4366 C CZ  . TYR D 1 221 ? 165.679 169.043 168.547 1.00 34.85 ? 221 TYR D CZ  1 
ATOM 4367 O OH  . TYR D 1 221 ? 165.252 170.321 168.823 1.00 40.38 ? 221 TYR D OH  1 
ATOM 4368 N N   . GLN D 1 222 ? 169.032 162.447 168.726 1.00 28.93 ? 222 GLN D N   1 
ATOM 4369 C CA  . GLN D 1 222 ? 169.554 161.109 168.488 1.00 19.01 ? 222 GLN D CA  1 
ATOM 4370 C C   . GLN D 1 222 ? 168.534 160.071 168.931 1.00 20.66 ? 222 GLN D C   1 
ATOM 4371 O O   . GLN D 1 222 ? 167.970 160.177 170.025 1.00 30.48 ? 222 GLN D O   1 
ATOM 4372 C CB  . GLN D 1 222 ? 170.875 160.899 169.229 1.00 23.57 ? 222 GLN D CB  1 
ATOM 4373 C CG  . GLN D 1 222 ? 172.025 161.744 168.714 1.00 31.19 ? 222 GLN D CG  1 
ATOM 4374 C CD  . GLN D 1 222 ? 173.326 161.450 169.435 1.00 31.12 ? 222 GLN D CD  1 
ATOM 4375 O OE1 . GLN D 1 222 ? 173.352 160.692 170.405 1.00 25.97 ? 222 GLN D OE1 1 
ATOM 4376 N NE2 . GLN D 1 222 ? 174.411 162.051 168.967 1.00 30.01 ? 222 GLN D NE2 1 
ATOM 4377 N N   . ARG D 1 223 ? 168.302 159.074 168.080 1.00 26.00 ? 223 ARG D N   1 
ATOM 4378 C CA  . ARG D 1 223 ? 167.431 157.944 168.407 1.00 34.43 ? 223 ARG D CA  1 
ATOM 4379 C C   . ARG D 1 223 ? 168.099 156.686 167.863 1.00 30.07 ? 223 ARG D C   1 
ATOM 4380 O O   . ARG D 1 223 ? 168.080 156.445 166.652 1.00 23.53 ? 223 ARG D O   1 
ATOM 4381 C CB  . ARG D 1 223 ? 166.033 158.127 167.832 1.00 31.74 ? 223 ARG D CB  1 
ATOM 4382 C CG  . ARG D 1 223 ? 165.148 156.899 167.972 1.00 30.02 ? 223 ARG D CG  1 
ATOM 4383 C CD  . ARG D 1 223 ? 163.790 157.119 167.332 1.00 34.03 ? 223 ARG D CD  1 
ATOM 4384 N NE  . ARG D 1 223 ? 162.882 157.842 168.213 1.00 41.45 ? 223 ARG D NE  1 
ATOM 4385 C CZ  . ARG D 1 223 ? 162.102 157.266 169.118 1.00 40.46 ? 223 ARG D CZ  1 
ATOM 4386 N NH1 . ARG D 1 223 ? 162.094 155.955 169.290 1.00 32.84 ? 223 ARG D NH1 1 
ATOM 4387 N NH2 . ARG D 1 223 ? 161.311 158.027 169.870 1.00 38.48 ? 223 ARG D NH2 1 
ATOM 4388 N N   . GLU D 1 224 ? 168.688 155.894 168.762 1.00 37.17 ? 224 GLU D N   1 
ATOM 4389 C CA  . GLU D 1 224 ? 169.414 154.676 168.393 1.00 35.63 ? 224 GLU D CA  1 
ATOM 4390 C C   . GLU D 1 224 ? 170.510 154.976 167.373 1.00 31.88 ? 224 GLU D C   1 
ATOM 4391 O O   . GLU D 1 224 ? 170.770 154.188 166.463 1.00 30.40 ? 224 GLU D O   1 
ATOM 4392 C CB  . GLU D 1 224 ? 168.462 153.600 167.868 1.00 36.99 ? 224 GLU D CB  1 
ATOM 4393 C CG  . GLU D 1 224 ? 167.220 153.401 168.720 1.00 38.56 ? 224 GLU D CG  1 
ATOM 4394 C CD  . GLU D 1 224 ? 166.086 152.752 167.953 1.00 39.04 ? 224 GLU D CD  1 
ATOM 4395 O OE1 . GLU D 1 224 ? 166.365 151.891 167.092 1.00 44.99 ? 224 GLU D OE1 1 
ATOM 4396 O OE2 . GLU D 1 224 ? 164.916 153.104 168.209 1.00 37.17 ? 224 GLU D OE2 1 
ATOM 4397 N N   . SER D 1 225 ? 171.162 156.123 167.534 1.00 30.11 ? 225 SER D N   1 
ATOM 4398 C CA  . SER D 1 225 ? 172.148 156.613 166.586 1.00 28.70 ? 225 SER D CA  1 
ATOM 4399 C C   . SER D 1 225 ? 173.482 156.843 167.286 1.00 29.20 ? 225 SER D C   1 
ATOM 4400 O O   . SER D 1 225 ? 173.598 156.741 168.510 1.00 39.53 ? 225 SER D O   1 
ATOM 4401 C CB  . SER D 1 225 ? 171.668 157.905 165.917 1.00 30.27 ? 225 SER D CB  1 
ATOM 4402 O OG  . SER D 1 225 ? 170.467 157.689 165.196 1.00 37.64 ? 225 SER D OG  1 
ATOM 4403 N N   . GLN D 1 226 ? 174.500 157.152 166.487 1.00 33.40 ? 226 GLN D N   1 
ATOM 4404 C CA  . GLN D 1 226 ? 175.843 157.380 167.000 1.00 32.84 ? 226 GLN D CA  1 
ATOM 4405 C C   . GLN D 1 226 ? 176.438 158.616 166.343 1.00 32.49 ? 226 GLN D C   1 
ATOM 4406 O O   . GLN D 1 226 ? 176.267 158.833 165.140 1.00 32.50 ? 226 GLN D O   1 
ATOM 4407 C CB  . GLN D 1 226 ? 176.751 156.168 166.754 1.00 20.31 ? 226 GLN D CB  1 
ATOM 4408 C CG  . GLN D 1 226 ? 176.439 154.967 167.632 1.00 24.05 ? 226 GLN D CG  1 
ATOM 4409 C CD  . GLN D 1 226 ? 175.300 154.127 167.087 1.00 30.51 ? 226 GLN D CD  1 
ATOM 4410 O OE1 . GLN D 1 226 ? 175.152 153.973 165.874 1.00 31.21 ? 226 GLN D OE1 1 
ATOM 4411 N NE2 . GLN D 1 226 ? 174.487 153.582 167.982 1.00 34.29 ? 226 GLN D NE2 1 
ATOM 4412 N N   . ALA D 1 227 ? 177.134 159.423 167.142 1.00 24.60 ? 227 ALA D N   1 
ATOM 4413 C CA  . ALA D 1 227 ? 177.842 160.597 166.654 1.00 21.13 ? 227 ALA D CA  1 
ATOM 4414 C C   . ALA D 1 227 ? 179.258 160.579 167.205 1.00 27.62 ? 227 ALA D C   1 
ATOM 4415 O O   . ALA D 1 227 ? 179.453 160.425 168.415 1.00 26.65 ? 227 ALA D O   1 
ATOM 4416 C CB  . ALA D 1 227 ? 177.128 161.890 167.058 1.00 25.28 ? 227 ALA D CB  1 
ATOM 4417 N N   . TYR D 1 228 ? 180.240 160.736 166.321 1.00 37.96 ? 228 TYR D N   1 
ATOM 4418 C CA  . TYR D 1 228 ? 181.649 160.701 166.691 1.00 32.61 ? 228 TYR D CA  1 
ATOM 4419 C C   . TYR D 1 228 ? 182.290 162.027 166.309 1.00 28.12 ? 228 TYR D C   1 
ATOM 4420 O O   . TYR D 1 228 ? 182.248 162.426 165.140 1.00 41.58 ? 228 TYR D O   1 
ATOM 4421 C CB  . TYR D 1 228 ? 182.366 159.536 166.007 1.00 24.71 ? 228 TYR D CB  1 
ATOM 4422 C CG  . TYR D 1 228 ? 181.875 158.176 166.446 1.00 26.42 ? 228 TYR D CG  1 
ATOM 4423 C CD1 . TYR D 1 228 ? 180.734 157.615 165.889 1.00 24.15 ? 228 TYR D CD1 1 
ATOM 4424 C CD2 . TYR D 1 228 ? 182.553 157.454 167.419 1.00 29.54 ? 228 TYR D CD2 1 
ATOM 4425 C CE1 . TYR D 1 228 ? 180.281 156.373 166.289 1.00 30.89 ? 228 TYR D CE1 1 
ATOM 4426 C CE2 . TYR D 1 228 ? 182.108 156.210 167.824 1.00 32.18 ? 228 TYR D CE2 1 
ATOM 4427 C CZ  . TYR D 1 228 ? 180.971 155.675 167.256 1.00 30.31 ? 228 TYR D CZ  1 
ATOM 4428 O OH  . TYR D 1 228 ? 180.522 154.437 167.656 1.00 33.57 ? 228 TYR D OH  1 
ATOM 4429 N N   . TYR D 1 229 ? 182.884 162.700 167.288 1.00 21.12 ? 229 TYR D N   1 
ATOM 4430 C CA  . TYR D 1 229 ? 183.512 163.993 167.057 1.00 17.80 ? 229 TYR D CA  1 
ATOM 4431 C C   . TYR D 1 229 ? 185.022 163.912 167.247 1.00 24.83 ? 229 TYR D C   1 
ATOM 4432 O O   . TYR D 1 229 ? 185.502 163.516 168.308 1.00 35.68 ? 229 TYR D O   1 
ATOM 4433 C CB  . TYR D 1 229 ? 182.919 165.050 167.993 1.00 29.15 ? 229 TYR D CB  1 
ATOM 4434 C CG  . TYR D 1 229 ? 181.427 165.244 167.834 1.00 32.70 ? 229 TYR D CG  1 
ATOM 4435 C CD1 . TYR D 1 229 ? 180.920 166.175 166.937 1.00 25.81 ? 229 TYR D CD1 1 
ATOM 4436 C CD2 . TYR D 1 229 ? 180.526 164.499 168.584 1.00 26.63 ? 229 TYR D CD2 1 
ATOM 4437 C CE1 . TYR D 1 229 ? 179.559 166.356 166.789 1.00 23.56 ? 229 TYR D CE1 1 
ATOM 4438 C CE2 . TYR D 1 229 ? 179.163 164.672 168.442 1.00 23.50 ? 229 TYR D CE2 1 
ATOM 4439 C CZ  . TYR D 1 229 ? 178.685 165.602 167.544 1.00 31.98 ? 229 TYR D CZ  1 
ATOM 4440 O OH  . TYR D 1 229 ? 177.329 165.780 167.400 1.00 37.18 ? 229 TYR D OH  1 
ATOM 4441 N N   . GLY E 1 92  ? 108.466 165.633 143.482 1.00 20.68 ? 92  GLY E N   1 
ATOM 4442 C CA  . GLY E 1 92  ? 109.332 164.522 143.826 1.00 21.41 ? 92  GLY E CA  1 
ATOM 4443 C C   . GLY E 1 92  ? 110.511 164.370 142.885 1.00 23.11 ? 92  GLY E C   1 
ATOM 4444 O O   . GLY E 1 92  ? 110.747 163.293 142.339 1.00 20.48 ? 92  GLY E O   1 
ATOM 4445 N N   . TRP E 1 93  ? 111.254 165.456 142.697 1.00 18.12 ? 93  TRP E N   1 
ATOM 4446 C CA  . TRP E 1 93  ? 112.407 165.458 141.814 1.00 8.04  ? 93  TRP E CA  1 
ATOM 4447 C C   . TRP E 1 93  ? 113.649 164.989 142.567 1.00 13.07 ? 93  TRP E C   1 
ATOM 4448 O O   . TRP E 1 93  ? 113.603 164.652 143.753 1.00 20.48 ? 93  TRP E O   1 
ATOM 4449 C CB  . TRP E 1 93  ? 112.615 166.847 141.214 1.00 14.88 ? 93  TRP E CB  1 
ATOM 4450 C CG  . TRP E 1 93  ? 112.720 167.934 142.241 1.00 13.87 ? 93  TRP E CG  1 
ATOM 4451 C CD1 . TRP E 1 93  ? 111.698 168.672 142.759 1.00 14.01 ? 93  TRP E CD1 1 
ATOM 4452 C CD2 . TRP E 1 93  ? 113.917 168.404 142.873 1.00 18.34 ? 93  TRP E CD2 1 
ATOM 4453 N NE1 . TRP E 1 93  ? 112.182 169.574 143.676 1.00 12.85 ? 93  TRP E NE1 1 
ATOM 4454 C CE2 . TRP E 1 93  ? 113.542 169.430 143.763 1.00 14.76 ? 93  TRP E CE2 1 
ATOM 4455 C CE3 . TRP E 1 93  ? 115.267 168.059 142.773 1.00 13.41 ? 93  TRP E CE3 1 
ATOM 4456 C CZ2 . TRP E 1 93  ? 114.468 170.110 144.550 1.00 16.24 ? 93  TRP E CZ2 1 
ATOM 4457 C CZ3 . TRP E 1 93  ? 116.185 168.737 143.553 1.00 16.46 ? 93  TRP E CZ3 1 
ATOM 4458 C CH2 . TRP E 1 93  ? 115.781 169.751 144.429 1.00 14.58 ? 93  TRP E CH2 1 
ATOM 4459 N N   . GLY E 1 94  ? 114.781 164.966 141.869 1.00 12.32 ? 94  GLY E N   1 
ATOM 4460 C CA  . GLY E 1 94  ? 116.024 164.538 142.475 1.00 20.82 ? 94  GLY E CA  1 
ATOM 4461 C C   . GLY E 1 94  ? 117.257 165.024 141.744 1.00 1.63  ? 94  GLY E C   1 
ATOM 4462 O O   . GLY E 1 94  ? 117.346 164.917 140.518 1.00 6.23  ? 94  GLY E O   1 
ATOM 4463 N N   . GLN E 1 95  ? 118.218 165.559 142.489 1.00 3.89  ? 95  GLN E N   1 
ATOM 4464 C CA  . GLN E 1 95  ? 119.486 166.016 141.937 1.00 7.12  ? 95  GLN E CA  1 
ATOM 4465 C C   . GLN E 1 95  ? 120.597 165.097 142.421 1.00 14.08 ? 95  GLN E C   1 
ATOM 4466 O O   . GLN E 1 95  ? 120.744 164.877 143.629 1.00 11.67 ? 95  GLN E O   1 
ATOM 4467 C CB  . GLN E 1 95  ? 119.774 167.464 142.342 1.00 20.06 ? 95  GLN E CB  1 
ATOM 4468 C CG  . GLN E 1 95  ? 119.112 168.501 141.449 1.00 12.05 ? 95  GLN E CG  1 
ATOM 4469 C CD  . GLN E 1 95  ? 119.356 169.920 141.926 1.00 13.50 ? 95  GLN E CD  1 
ATOM 4470 O OE1 . GLN E 1 95  ? 119.092 170.252 143.082 1.00 21.18 ? 95  GLN E OE1 1 
ATOM 4471 N NE2 . GLN E 1 95  ? 119.860 170.765 141.035 1.00 9.13  ? 95  GLN E NE2 1 
ATOM 4472 N N   . GLY E 1 96  ? 121.373 164.564 141.482 1.00 19.23 ? 96  GLY E N   1 
ATOM 4473 C CA  . GLY E 1 96  ? 122.429 163.640 141.841 1.00 15.72 ? 96  GLY E CA  1 
ATOM 4474 C C   . GLY E 1 96  ? 123.533 164.312 142.636 1.00 11.39 ? 96  GLY E C   1 
ATOM 4475 O O   . GLY E 1 96  ? 123.804 165.504 142.493 1.00 15.84 ? 96  GLY E O   1 
ATOM 4476 N N   . GLY E 1 97  ? 124.174 163.523 143.495 1.00 26.07 ? 97  GLY E N   1 
ATOM 4477 C CA  . GLY E 1 97  ? 125.255 164.047 144.305 1.00 21.87 ? 97  GLY E CA  1 
ATOM 4478 C C   . GLY E 1 97  ? 126.441 164.476 143.462 1.00 19.44 ? 97  GLY E C   1 
ATOM 4479 O O   . GLY E 1 97  ? 126.764 163.872 142.439 1.00 24.60 ? 97  GLY E O   1 
ATOM 4480 N N   . THR E 1 98  ? 127.100 165.538 143.908 1.00 16.16 ? 98  THR E N   1 
ATOM 4481 C CA  . THR E 1 98  ? 128.227 166.117 143.191 1.00 20.45 ? 98  THR E CA  1 
ATOM 4482 C C   . THR E 1 98  ? 129.528 165.667 143.843 1.00 28.17 ? 98  THR E C   1 
ATOM 4483 O O   . THR E 1 98  ? 129.766 165.948 145.022 1.00 24.95 ? 98  THR E O   1 
ATOM 4484 C CB  . THR E 1 98  ? 128.142 167.642 143.173 1.00 27.73 ? 98  THR E CB  1 
ATOM 4485 O OG1 . THR E 1 98  ? 126.970 168.051 142.456 1.00 34.87 ? 98  THR E OG1 1 
ATOM 4486 C CG2 . THR E 1 98  ? 129.369 168.228 142.498 1.00 25.45 ? 98  THR E CG2 1 
ATOM 4487 N N   . HIS E 1 99  ? 130.362 164.971 143.075 1.00 29.53 ? 99  HIS E N   1 
ATOM 4488 C CA  . HIS E 1 99  ? 131.709 164.589 143.493 1.00 21.77 ? 99  HIS E CA  1 
ATOM 4489 C C   . HIS E 1 99  ? 132.672 165.282 142.539 1.00 18.56 ? 99  HIS E C   1 
ATOM 4490 O O   . HIS E 1 99  ? 133.128 164.697 141.554 1.00 27.14 ? 99  HIS E O   1 
ATOM 4491 C CB  . HIS E 1 99  ? 131.887 163.064 143.483 1.00 23.79 ? 99  HIS E CB  1 
ATOM 4492 C CG  . HIS E 1 99  ? 130.791 162.323 144.185 1.00 31.37 ? 99  HIS E CG  1 
ATOM 4493 N ND1 . HIS E 1 99  ? 129.523 162.196 143.661 1.00 26.06 ? 99  HIS E ND1 1 
ATOM 4494 C CD2 . HIS E 1 99  ? 130.776 161.668 145.369 1.00 33.68 ? 99  HIS E CD2 1 
ATOM 4495 C CE1 . HIS E 1 99  ? 128.773 161.495 144.493 1.00 25.46 ? 99  HIS E CE1 1 
ATOM 4496 N NE2 . HIS E 1 99  ? 129.509 161.163 145.538 1.00 32.69 ? 99  HIS E NE2 1 
ATOM 4497 N N   . SER E 1 100 ? 132.991 166.536 142.845 1.00 24.22 ? 100 SER E N   1 
ATOM 4498 C CA  . SER E 1 100 ? 133.757 167.392 141.951 1.00 20.38 ? 100 SER E CA  1 
ATOM 4499 C C   . SER E 1 100 ? 134.977 167.936 142.674 1.00 22.99 ? 100 SER E C   1 
ATOM 4500 O O   . SER E 1 100 ? 134.907 168.277 143.857 1.00 27.23 ? 100 SER E O   1 
ATOM 4501 C CB  . SER E 1 100 ? 132.898 168.548 141.427 1.00 26.48 ? 100 SER E CB  1 
ATOM 4502 O OG  . SER E 1 100 ? 131.935 168.085 140.496 1.00 26.03 ? 100 SER E OG  1 
ATOM 4503 N N   . GLN E 1 101 ? 136.092 168.022 141.958 1.00 21.79 ? 101 GLN E N   1 
ATOM 4504 C CA  . GLN E 1 101 ? 137.343 168.502 142.528 1.00 20.71 ? 101 GLN E CA  1 
ATOM 4505 C C   . GLN E 1 101 ? 137.893 169.634 141.678 1.00 10.68 ? 101 GLN E C   1 
ATOM 4506 O O   . GLN E 1 101 ? 138.074 169.473 140.469 1.00 30.42 ? 101 GLN E O   1 
ATOM 4507 C CB  . GLN E 1 101 ? 138.375 167.373 142.626 1.00 12.44 ? 101 GLN E CB  1 
ATOM 4508 C CG  . GLN E 1 101 ? 138.027 166.301 143.645 1.00 10.43 ? 101 GLN E CG  1 
ATOM 4509 C CD  . GLN E 1 101 ? 137.093 165.245 143.085 1.00 15.80 ? 101 GLN E CD  1 
ATOM 4510 O OE1 . GLN E 1 101 ? 137.149 164.918 141.900 1.00 20.91 ? 101 GLN E OE1 1 
ATOM 4511 N NE2 . GLN E 1 101 ? 136.230 164.706 143.937 1.00 23.88 ? 101 GLN E NE2 1 
ATOM 4512 N N   . TRP E 1 102 ? 138.164 170.777 142.312 1.00 6.30  ? 102 TRP E N   1 
ATOM 4513 C CA  . TRP E 1 102 ? 138.799 171.874 141.588 1.00 1.57  ? 102 TRP E CA  1 
ATOM 4514 C C   . TRP E 1 102 ? 140.198 171.498 141.121 1.00 18.29 ? 102 TRP E C   1 
ATOM 4515 O O   . TRP E 1 102 ? 140.686 172.037 140.120 1.00 18.74 ? 102 TRP E O   1 
ATOM 4516 C CB  . TRP E 1 102 ? 138.848 173.128 142.461 1.00 12.63 ? 102 TRP E CB  1 
ATOM 4517 C CG  . TRP E 1 102 ? 139.317 174.344 141.723 1.00 14.90 ? 102 TRP E CG  1 
ATOM 4518 C CD1 . TRP E 1 102 ? 140.525 174.963 141.850 1.00 13.41 ? 102 TRP E CD1 1 
ATOM 4519 C CD2 . TRP E 1 102 ? 138.590 175.081 140.734 1.00 11.77 ? 102 TRP E CD2 1 
ATOM 4520 N NE1 . TRP E 1 102 ? 140.593 176.044 141.005 1.00 9.17  ? 102 TRP E NE1 1 
ATOM 4521 C CE2 . TRP E 1 102 ? 139.418 176.137 140.309 1.00 4.61  ? 102 TRP E CE2 1 
ATOM 4522 C CE3 . TRP E 1 102 ? 137.317 174.952 140.171 1.00 14.49 ? 102 TRP E CE3 1 
ATOM 4523 C CZ2 . TRP E 1 102 ? 139.016 177.059 139.345 1.00 8.88  ? 102 TRP E CZ2 1 
ATOM 4524 C CZ3 . TRP E 1 102 ? 136.920 175.868 139.214 1.00 9.74  ? 102 TRP E CZ3 1 
ATOM 4525 C CH2 . TRP E 1 102 ? 137.766 176.907 138.811 1.00 9.87  ? 102 TRP E CH2 1 
ATOM 4526 N N   . ASN E 1 103 ? 140.853 170.579 141.825 1.00 29.15 ? 103 ASN E N   1 
ATOM 4527 C CA  . ASN E 1 103 ? 142.172 170.092 141.430 1.00 19.27 ? 103 ASN E CA  1 
ATOM 4528 C C   . ASN E 1 103 ? 142.333 168.692 142.006 1.00 23.02 ? 103 ASN E C   1 
ATOM 4529 O O   . ASN E 1 103 ? 142.381 168.528 143.229 1.00 20.73 ? 103 ASN E O   1 
ATOM 4530 C CB  . ASN E 1 103 ? 143.274 171.022 141.926 1.00 10.46 ? 103 ASN E CB  1 
ATOM 4531 C CG  . ASN E 1 103 ? 144.631 170.678 141.345 1.00 23.51 ? 103 ASN E CG  1 
ATOM 4532 O OD1 . ASN E 1 103 ? 144.733 170.203 140.215 1.00 13.51 ? 103 ASN E OD1 1 
ATOM 4533 N ND2 . ASN E 1 103 ? 145.683 170.918 142.118 1.00 25.90 ? 103 ASN E ND2 1 
ATOM 4534 N N   . LYS E 1 104 ? 142.413 167.691 141.132 1.00 14.47 ? 104 LYS E N   1 
ATOM 4535 C CA  . LYS E 1 104 ? 142.538 166.290 141.536 1.00 13.11 ? 104 LYS E CA  1 
ATOM 4536 C C   . LYS E 1 104 ? 143.726 165.667 140.817 1.00 21.71 ? 104 LYS E C   1 
ATOM 4537 O O   . LYS E 1 104 ? 143.557 164.906 139.853 1.00 26.40 ? 104 LYS E O   1 
ATOM 4538 C CB  . LYS E 1 104 ? 141.252 165.514 141.246 1.00 11.00 ? 104 LYS E CB  1 
ATOM 4539 C CG  . LYS E 1 104 ? 141.194 164.145 141.901 1.00 14.11 ? 104 LYS E CG  1 
ATOM 4540 C CD  . LYS E 1 104 ? 140.012 163.339 141.394 1.00 14.28 ? 104 LYS E CD  1 
ATOM 4541 C CE  . LYS E 1 104 ? 140.226 161.850 141.611 1.00 20.12 ? 104 LYS E CE  1 
ATOM 4542 N NZ  . LYS E 1 104 ? 140.297 161.502 143.056 1.00 22.75 ? 104 LYS E NZ  1 
ATOM 4543 N N   . PRO E 1 105 ? 144.950 165.971 141.254 1.00 27.36 ? 105 PRO E N   1 
ATOM 4544 C CA  . PRO E 1 105 ? 146.123 165.315 140.667 1.00 24.88 ? 105 PRO E CA  1 
ATOM 4545 C C   . PRO E 1 105 ? 146.466 164.017 141.381 1.00 27.76 ? 105 PRO E C   1 
ATOM 4546 O O   . PRO E 1 105 ? 146.608 163.995 142.607 1.00 24.01 ? 105 PRO E O   1 
ATOM 4547 C CB  . PRO E 1 105 ? 147.231 166.362 140.833 1.00 20.61 ? 105 PRO E CB  1 
ATOM 4548 C CG  . PRO E 1 105 ? 146.755 167.280 141.943 1.00 27.07 ? 105 PRO E CG  1 
ATOM 4549 C CD  . PRO E 1 105 ? 145.328 166.946 142.290 1.00 26.96 ? 105 PRO E CD  1 
ATOM 4550 N N   . SER E 1 106 ? 146.604 162.932 140.627 1.00 27.43 ? 106 SER E N   1 
ATOM 4551 C CA  . SER E 1 106 ? 146.890 161.620 141.189 1.00 26.39 ? 106 SER E CA  1 
ATOM 4552 C C   . SER E 1 106 ? 148.366 161.295 141.010 1.00 37.67 ? 106 SER E C   1 
ATOM 4553 O O   . SER E 1 106 ? 148.881 161.328 139.888 1.00 36.63 ? 106 SER E O   1 
ATOM 4554 C CB  . SER E 1 106 ? 146.028 160.545 140.527 1.00 30.29 ? 106 SER E CB  1 
ATOM 4555 O OG  . SER E 1 106 ? 146.131 159.312 141.219 1.00 39.13 ? 106 SER E OG  1 
ATOM 4556 N N   . LYS E 1 107 ? 149.035 160.980 142.116 1.00 36.62 ? 107 LYS E N   1 
ATOM 4557 C CA  . LYS E 1 107 ? 150.450 160.627 142.129 1.00 32.08 ? 107 LYS E CA  1 
ATOM 4558 C C   . LYS E 1 107 ? 151.333 161.622 141.369 1.00 32.37 ? 107 LYS E C   1 
ATOM 4559 O O   . LYS E 1 107 ? 152.006 161.249 140.402 1.00 34.11 ? 107 LYS E O   1 
ATOM 4560 C CB  . LYS E 1 107 ? 150.650 159.218 141.591 1.00 30.25 ? 107 LYS E CB  1 
ATOM 4561 C CG  . LYS E 1 107 ? 149.909 158.142 142.367 1.00 33.37 ? 107 LYS E CG  1 
ATOM 4562 C CD  . LYS E 1 107 ? 149.793 156.863 141.555 1.00 33.55 ? 107 LYS E CD  1 
ATOM 4563 C CE  . LYS E 1 107 ? 148.912 155.841 142.254 1.00 31.41 ? 107 LYS E CE  1 
ATOM 4564 N NZ  . LYS E 1 107 ? 148.792 154.585 141.465 1.00 34.53 ? 107 LYS E NZ  1 
ATOM 4565 N N   . PRO E 1 108 ? 151.355 162.898 141.777 1.00 30.95 ? 108 PRO E N   1 
ATOM 4566 C CA  . PRO E 1 108 ? 152.263 163.861 141.139 1.00 28.77 ? 108 PRO E CA  1 
ATOM 4567 C C   . PRO E 1 108 ? 153.678 163.737 141.682 1.00 36.78 ? 108 PRO E C   1 
ATOM 4568 O O   . PRO E 1 108 ? 153.975 164.167 142.801 1.00 43.26 ? 108 PRO E O   1 
ATOM 4569 C CB  . PRO E 1 108 ? 151.625 165.214 141.484 1.00 27.38 ? 108 PRO E CB  1 
ATOM 4570 C CG  . PRO E 1 108 ? 150.978 164.987 142.796 1.00 28.40 ? 108 PRO E CG  1 
ATOM 4571 C CD  . PRO E 1 108 ? 150.577 163.526 142.861 1.00 31.51 ? 108 PRO E CD  1 
ATOM 4572 N N   . LYS E 1 109 ? 154.559 163.143 140.882 1.00 33.61 ? 109 LYS E N   1 
ATOM 4573 C CA  . LYS E 1 109 ? 155.970 163.003 141.224 1.00 28.35 ? 109 LYS E CA  1 
ATOM 4574 C C   . LYS E 1 109 ? 156.728 164.119 140.518 1.00 33.90 ? 109 LYS E C   1 
ATOM 4575 O O   . LYS E 1 109 ? 156.848 164.117 139.289 1.00 34.26 ? 109 LYS E O   1 
ATOM 4576 C CB  . LYS E 1 109 ? 156.496 161.628 140.817 1.00 23.60 ? 109 LYS E CB  1 
ATOM 4577 C CG  . LYS E 1 109 ? 155.955 160.487 141.663 1.00 31.99 ? 109 LYS E CG  1 
ATOM 4578 C CD  . LYS E 1 109 ? 156.447 159.140 141.161 1.00 35.40 ? 109 LYS E CD  1 
ATOM 4579 C CE  . LYS E 1 109 ? 155.893 158.003 142.004 1.00 33.48 ? 109 LYS E CE  1 
ATOM 4580 N NZ  . LYS E 1 109 ? 156.361 156.675 141.522 1.00 38.08 ? 109 LYS E NZ  1 
ATOM 4581 N N   . THR E 1 110 ? 157.239 165.071 141.293 1.00 29.95 ? 110 THR E N   1 
ATOM 4582 C CA  . THR E 1 110 ? 157.812 166.284 140.733 1.00 29.13 ? 110 THR E CA  1 
ATOM 4583 C C   . THR E 1 110 ? 159.134 166.601 141.409 1.00 28.75 ? 110 THR E C   1 
ATOM 4584 O O   . THR E 1 110 ? 159.274 166.445 142.626 1.00 36.30 ? 110 THR E O   1 
ATOM 4585 C CB  . THR E 1 110 ? 156.852 167.471 140.890 1.00 31.82 ? 110 THR E CB  1 
ATOM 4586 O OG1 . THR E 1 110 ? 155.534 167.079 140.489 1.00 34.95 ? 110 THR E OG1 1 
ATOM 4587 C CG2 . THR E 1 110 ? 157.307 168.637 140.035 1.00 28.18 ? 110 THR E CG2 1 
ATOM 4588 N N   . ASN E 1 111 ? 160.103 167.044 140.612 1.00 32.50 ? 111 ASN E N   1 
ATOM 4589 C CA  . ASN E 1 111 ? 161.383 167.529 141.108 1.00 35.76 ? 111 ASN E CA  1 
ATOM 4590 C C   . ASN E 1 111 ? 161.608 168.931 140.564 1.00 29.82 ? 111 ASN E C   1 
ATOM 4591 O O   . ASN E 1 111 ? 161.597 169.136 139.345 1.00 29.82 ? 111 ASN E O   1 
ATOM 4592 C CB  . ASN E 1 111 ? 162.525 166.595 140.700 1.00 31.62 ? 111 ASN E CB  1 
ATOM 4593 C CG  . ASN E 1 111 ? 162.445 165.246 141.385 1.00 27.28 ? 111 ASN E CG  1 
ATOM 4594 O OD1 . ASN E 1 111 ? 162.846 165.100 142.540 1.00 29.74 ? 111 ASN E OD1 1 
ATOM 4595 N ND2 . ASN E 1 111 ? 161.927 164.252 140.676 1.00 31.69 ? 111 ASN E ND2 1 
ATOM 4596 N N   . MET E 1 112 ? 161.807 169.890 141.464 1.00 28.87 ? 112 MET E N   1 
ATOM 4597 C CA  . MET E 1 112 ? 162.020 171.279 141.086 1.00 20.10 ? 112 MET E CA  1 
ATOM 4598 C C   . MET E 1 112 ? 162.934 171.921 142.119 1.00 25.20 ? 112 MET E C   1 
ATOM 4599 O O   . MET E 1 112 ? 163.373 171.275 143.073 1.00 30.65 ? 112 MET E O   1 
ATOM 4600 C CB  . MET E 1 112 ? 160.690 172.026 140.961 1.00 22.06 ? 112 MET E CB  1 
ATOM 4601 C CG  . MET E 1 112 ? 159.786 171.882 142.168 1.00 25.37 ? 112 MET E CG  1 
ATOM 4602 S SD  . MET E 1 112 ? 158.102 172.413 141.819 1.00 36.99 ? 112 MET E SD  1 
ATOM 4603 C CE  . MET E 1 112 ? 157.255 171.808 143.272 1.00 25.12 ? 112 MET E CE  1 
ATOM 4604 N N   . LYS E 1 113 ? 163.241 173.201 141.912 1.00 26.64 ? 113 LYS E N   1 
ATOM 4605 C CA  . LYS E 1 113 ? 164.095 173.934 142.840 1.00 29.89 ? 113 LYS E CA  1 
ATOM 4606 C C   . LYS E 1 113 ? 163.361 175.085 143.515 1.00 31.54 ? 113 LYS E C   1 
ATOM 4607 O O   . LYS E 1 113 ? 163.305 175.131 144.747 1.00 37.97 ? 113 LYS E O   1 
ATOM 4608 C CB  . LYS E 1 113 ? 165.347 174.442 142.113 1.00 28.96 ? 113 LYS E CB  1 
ATOM 4609 C CG  . LYS E 1 113 ? 166.445 174.932 143.040 1.00 33.46 ? 113 LYS E CG  1 
ATOM 4610 C CD  . LYS E 1 113 ? 167.643 175.446 142.261 1.00 31.25 ? 113 LYS E CD  1 
ATOM 4611 C CE  . LYS E 1 113 ? 168.642 176.127 143.182 1.00 36.76 ? 113 LYS E CE  1 
ATOM 4612 N NZ  . LYS E 1 113 ? 169.766 176.747 142.426 1.00 38.57 ? 113 LYS E NZ  1 
ATOM 4613 N N   . HIS E 1 114 ? 162.781 176.011 142.753 1.00 33.67 ? 114 HIS E N   1 
ATOM 4614 C CA  . HIS E 1 114 ? 162.184 177.214 143.317 1.00 34.05 ? 114 HIS E CA  1 
ATOM 4615 C C   . HIS E 1 114 ? 160.740 177.349 142.862 1.00 31.66 ? 114 HIS E C   1 
ATOM 4616 O O   . HIS E 1 114 ? 160.447 177.234 141.667 1.00 37.45 ? 114 HIS E O   1 
ATOM 4617 C CB  . HIS E 1 114 ? 162.980 178.460 142.916 1.00 32.62 ? 114 HIS E CB  1 
ATOM 4618 C CG  . HIS E 1 114 ? 164.328 178.548 143.562 1.00 30.52 ? 114 HIS E CG  1 
ATOM 4619 N ND1 . HIS E 1 114 ? 164.711 177.725 144.598 1.00 31.54 ? 114 HIS E ND1 1 
ATOM 4620 C CD2 . HIS E 1 114 ? 165.384 179.359 143.315 1.00 37.57 ? 114 HIS E CD2 1 
ATOM 4621 C CE1 . HIS E 1 114 ? 165.943 178.026 144.965 1.00 32.97 ? 114 HIS E CE1 1 
ATOM 4622 N NE2 . HIS E 1 114 ? 166.375 179.014 144.201 1.00 41.34 ? 114 HIS E NE2 1 
ATOM 4623 N N   . VAL E 1 115 ? 159.847 177.589 143.815 1.00 18.65 ? 115 VAL E N   1 
ATOM 4624 C CA  . VAL E 1 115 ? 158.440 177.877 143.543 1.00 20.95 ? 115 VAL E CA  1 
ATOM 4625 C C   . VAL E 1 115 ? 158.153 179.234 144.172 1.00 29.71 ? 115 VAL E C   1 
ATOM 4626 O O   . VAL E 1 115 ? 157.839 179.327 145.363 1.00 24.09 ? 115 VAL E O   1 
ATOM 4627 C CB  . VAL E 1 115 ? 157.503 176.797 144.093 1.00 22.37 ? 115 VAL E CB  1 
ATOM 4628 C CG1 . VAL E 1 115 ? 156.090 177.009 143.573 1.00 20.55 ? 115 VAL E CG1 1 
ATOM 4629 C CG2 . VAL E 1 115 ? 158.011 175.416 143.724 1.00 21.59 ? 115 VAL E CG2 1 
ATOM 4630 N N   . ALA E 1 116 ? 158.260 180.296 143.377 1.00 28.27 ? 116 ALA E N   1 
ATOM 4631 C CA  . ALA E 1 116 ? 158.071 181.660 143.854 1.00 19.56 ? 116 ALA E CA  1 
ATOM 4632 C C   . ALA E 1 116 ? 156.843 182.258 143.186 1.00 22.30 ? 116 ALA E C   1 
ATOM 4633 O O   . ALA E 1 116 ? 156.797 182.373 141.956 1.00 21.11 ? 116 ALA E O   1 
ATOM 4634 C CB  . ALA E 1 116 ? 159.306 182.516 143.570 1.00 24.56 ? 116 ALA E CB  1 
ATOM 4635 N N   . GLY E 1 117 ? 155.856 182.633 143.993 1.00 23.46 ? 117 GLY E N   1 
ATOM 4636 C CA  . GLY E 1 117 ? 154.664 183.287 143.475 1.00 22.14 ? 117 GLY E CA  1 
ATOM 4637 C C   . GLY E 1 117 ? 153.907 182.468 142.453 1.00 15.74 ? 117 GLY E C   1 
ATOM 4638 O O   . GLY E 1 117 ? 153.344 183.031 141.506 1.00 20.89 ? 117 GLY E O   1 
ATOM 4639 N N   . ALA E 1 118 ? 153.860 181.152 142.634 1.00 16.73 ? 118 ALA E N   1 
ATOM 4640 C CA  . ALA E 1 118 ? 153.329 180.256 141.619 1.00 17.08 ? 118 ALA E CA  1 
ATOM 4641 C C   . ALA E 1 118 ? 152.560 179.133 142.305 1.00 12.57 ? 118 ALA E C   1 
ATOM 4642 O O   . ALA E 1 118 ? 152.268 179.189 143.503 1.00 17.19 ? 118 ALA E O   1 
ATOM 4643 C CB  . ALA E 1 118 ? 154.461 179.722 140.733 1.00 19.48 ? 118 ALA E CB  1 
ATOM 4644 N N   . ALA E 1 119 ? 152.215 178.111 141.527 1.00 15.85 ? 119 ALA E N   1 
ATOM 4645 C CA  . ALA E 1 119 ? 151.571 176.912 142.038 1.00 21.52 ? 119 ALA E CA  1 
ATOM 4646 C C   . ALA E 1 119 ? 152.238 175.699 141.410 1.00 22.91 ? 119 ALA E C   1 
ATOM 4647 O O   . ALA E 1 119 ? 152.545 175.702 140.215 1.00 25.54 ? 119 ALA E O   1 
ATOM 4648 C CB  . ALA E 1 119 ? 150.068 176.904 141.737 1.00 26.27 ? 119 ALA E CB  1 
ATOM 4649 N N   . ALA E 1 120 ? 152.458 174.665 142.216 1.00 24.69 ? 120 ALA E N   1 
ATOM 4650 C CA  . ALA E 1 120 ? 153.146 173.479 141.733 1.00 22.52 ? 120 ALA E CA  1 
ATOM 4651 C C   . ALA E 1 120 ? 152.776 172.291 142.608 1.00 20.24 ? 120 ALA E C   1 
ATOM 4652 O O   . ALA E 1 120 ? 152.237 172.449 143.706 1.00 15.88 ? 120 ALA E O   1 
ATOM 4653 C CB  . ALA E 1 120 ? 154.663 173.684 141.707 1.00 22.31 ? 120 ALA E CB  1 
ATOM 4654 N N   . ALA E 1 121 ? 153.076 171.096 142.095 1.00 26.64 ? 121 ALA E N   1 
ATOM 4655 C CA  . ALA E 1 121 ? 152.829 169.838 142.801 1.00 20.64 ? 121 ALA E CA  1 
ATOM 4656 C C   . ALA E 1 121 ? 151.367 169.706 143.222 1.00 14.52 ? 121 ALA E C   1 
ATOM 4657 O O   . ALA E 1 121 ? 151.059 169.284 144.338 1.00 24.01 ? 121 ALA E O   1 
ATOM 4658 C CB  . ALA E 1 121 ? 153.761 169.686 144.005 1.00 21.13 ? 121 ALA E CB  1 
ATOM 4659 N N   . GLY E 1 122 ? 150.460 170.068 142.319 1.00 16.58 ? 122 GLY E N   1 
ATOM 4660 C CA  . GLY E 1 122 ? 149.039 169.925 142.565 1.00 17.78 ? 122 GLY E CA  1 
ATOM 4661 C C   . GLY E 1 122 ? 148.502 170.779 143.694 1.00 27.05 ? 122 GLY E C   1 
ATOM 4662 O O   . GLY E 1 122 ? 147.741 170.296 144.538 1.00 25.18 ? 122 GLY E O   1 
ATOM 4663 N N   . ALA E 1 123 ? 148.883 172.053 143.715 1.00 29.98 ? 123 ALA E N   1 
ATOM 4664 C CA  . ALA E 1 123 ? 148.478 172.983 144.758 1.00 17.91 ? 123 ALA E CA  1 
ATOM 4665 C C   . ALA E 1 123 ? 147.641 174.104 144.159 1.00 23.11 ? 123 ALA E C   1 
ATOM 4666 O O   . ALA E 1 123 ? 147.905 174.559 143.042 1.00 27.15 ? 123 ALA E O   1 
ATOM 4667 C CB  . ALA E 1 123 ? 149.698 173.561 145.473 1.00 14.96 ? 123 ALA E CB  1 
ATOM 4668 N N   . VAL E 1 124 ? 146.633 174.551 144.905 1.00 22.29 ? 124 VAL E N   1 
ATOM 4669 C CA  . VAL E 1 124 ? 145.717 175.595 144.461 1.00 22.66 ? 124 VAL E CA  1 
ATOM 4670 C C   . VAL E 1 124 ? 146.011 176.868 145.240 1.00 21.01 ? 124 VAL E C   1 
ATOM 4671 O O   . VAL E 1 124 ? 146.018 176.857 146.475 1.00 29.05 ? 124 VAL E O   1 
ATOM 4672 C CB  . VAL E 1 124 ? 144.249 175.173 144.637 1.00 12.52 ? 124 VAL E CB  1 
ATOM 4673 C CG1 . VAL E 1 124 ? 143.345 176.047 143.787 1.00 22.96 ? 124 VAL E CG1 1 
ATOM 4674 C CG2 . VAL E 1 124 ? 144.075 173.710 144.275 1.00 21.31 ? 124 VAL E CG2 1 
ATOM 4675 N N   . VAL E 1 125 ? 146.256 177.960 144.523 1.00 23.70 ? 125 VAL E N   1 
ATOM 4676 C CA  . VAL E 1 125 ? 146.530 179.256 145.171 1.00 23.30 ? 125 VAL E CA  1 
ATOM 4677 C C   . VAL E 1 125 ? 145.185 179.961 145.312 1.00 25.73 ? 125 VAL E C   1 
ATOM 4678 O O   . VAL E 1 125 ? 144.792 180.808 144.508 1.00 20.16 ? 125 VAL E O   1 
ATOM 4679 C CB  . VAL E 1 125 ? 147.554 180.088 144.396 1.00 15.60 ? 125 VAL E CB  1 
ATOM 4680 C CG1 . VAL E 1 125 ? 147.929 181.330 145.188 1.00 18.99 ? 125 VAL E CG1 1 
ATOM 4681 C CG2 . VAL E 1 125 ? 148.786 179.260 144.094 1.00 19.98 ? 125 VAL E CG2 1 
ATOM 4682 N N   . GLY E 1 126 ? 144.470 179.617 146.377 1.00 32.52 ? 126 GLY E N   1 
ATOM 4683 C CA  . GLY E 1 126 ? 143.306 180.384 146.773 1.00 31.95 ? 126 GLY E CA  1 
ATOM 4684 C C   . GLY E 1 126 ? 141.994 180.060 146.092 1.00 27.90 ? 126 GLY E C   1 
ATOM 4685 O O   . GLY E 1 126 ? 141.896 180.069 144.862 1.00 20.23 ? 126 GLY E O   1 
ATOM 4686 N N   . GLY E 1 127 ? 140.972 179.776 146.896 1.00 34.95 ? 127 GLY E N   1 
ATOM 4687 C CA  . GLY E 1 127 ? 139.603 179.742 146.423 1.00 24.24 ? 127 GLY E CA  1 
ATOM 4688 C C   . GLY E 1 127 ? 138.858 180.949 146.953 1.00 23.88 ? 127 GLY E C   1 
ATOM 4689 O O   . GLY E 1 127 ? 138.570 181.022 148.151 1.00 26.23 ? 127 GLY E O   1 
ATOM 4690 N N   . LEU E 1 128 ? 138.547 181.902 146.071 1.00 28.08 ? 128 LEU E N   1 
ATOM 4691 C CA  . LEU E 1 128 ? 138.096 183.235 146.476 1.00 27.75 ? 128 LEU E CA  1 
ATOM 4692 C C   . LEU E 1 128 ? 139.103 183.886 147.418 1.00 20.50 ? 128 LEU E C   1 
ATOM 4693 O O   . LEU E 1 128 ? 138.738 184.571 148.375 1.00 30.31 ? 128 LEU E O   1 
ATOM 4694 C CB  . LEU E 1 128 ? 136.704 183.197 147.109 1.00 24.56 ? 128 LEU E CB  1 
ATOM 4695 C CG  . LEU E 1 128 ? 135.520 183.039 146.159 1.00 31.30 ? 128 LEU E CG  1 
ATOM 4696 C CD1 . LEU E 1 128 ? 134.249 182.737 146.926 1.00 26.36 ? 128 LEU E CD1 1 
ATOM 4697 C CD2 . LEU E 1 128 ? 135.361 184.306 145.351 1.00 31.54 ? 128 LEU E CD2 1 
ATOM 4698 N N   . GLY E 1 129 ? 140.385 183.676 147.136 1.00 18.68 ? 129 GLY E N   1 
ATOM 4699 C CA  . GLY E 1 129 ? 141.445 184.198 147.972 1.00 20.43 ? 129 GLY E CA  1 
ATOM 4700 C C   . GLY E 1 129 ? 142.816 183.973 147.372 1.00 18.98 ? 129 GLY E C   1 
ATOM 4701 O O   . GLY E 1 129 ? 142.962 183.905 146.148 1.00 27.51 ? 129 GLY E O   1 
ATOM 4702 N N   . GLY E 1 130 ? 143.828 183.855 148.224 1.00 18.01 ? 130 GLY E N   1 
ATOM 4703 C CA  . GLY E 1 130 ? 145.187 183.675 147.759 1.00 18.72 ? 130 GLY E CA  1 
ATOM 4704 C C   . GLY E 1 130 ? 146.098 184.788 148.227 1.00 22.00 ? 130 GLY E C   1 
ATOM 4705 O O   . GLY E 1 130 ? 146.344 184.934 149.427 1.00 23.80 ? 130 GLY E O   1 
ATOM 4706 N N   . TYR E 1 131 ? 146.602 185.582 147.288 1.00 36.73 ? 131 TYR E N   1 
ATOM 4707 C CA  . TYR E 1 131 ? 147.438 186.739 147.593 1.00 37.70 ? 131 TYR E CA  1 
ATOM 4708 C C   . TYR E 1 131 ? 146.683 187.966 147.096 1.00 35.99 ? 131 TYR E C   1 
ATOM 4709 O O   . TYR E 1 131 ? 146.889 188.431 145.972 1.00 30.29 ? 131 TYR E O   1 
ATOM 4710 C CB  . TYR E 1 131 ? 148.820 186.604 146.959 1.00 31.46 ? 131 TYR E CB  1 
ATOM 4711 C CG  . TYR E 1 131 ? 149.665 185.546 147.629 1.00 33.10 ? 131 TYR E CG  1 
ATOM 4712 C CD1 . TYR E 1 131 ? 149.446 184.199 147.379 1.00 33.66 ? 131 TYR E CD1 1 
ATOM 4713 C CD2 . TYR E 1 131 ? 150.665 185.892 148.529 1.00 34.31 ? 131 TYR E CD2 1 
ATOM 4714 C CE1 . TYR E 1 131 ? 150.206 183.225 147.994 1.00 29.12 ? 131 TYR E CE1 1 
ATOM 4715 C CE2 . TYR E 1 131 ? 151.430 184.924 149.151 1.00 35.75 ? 131 TYR E CE2 1 
ATOM 4716 C CZ  . TYR E 1 131 ? 151.195 183.592 148.879 1.00 36.00 ? 131 TYR E CZ  1 
ATOM 4717 O OH  . TYR E 1 131 ? 151.949 182.620 149.493 1.00 36.25 ? 131 TYR E OH  1 
ATOM 4718 N N   . MET E 1 132 ? 145.804 188.488 147.947 1.00 41.84 ? 132 MET E N   1 
ATOM 4719 C CA  . MET E 1 132 ? 144.906 189.588 147.608 1.00 40.74 ? 132 MET E CA  1 
ATOM 4720 C C   . MET E 1 132 ? 145.122 190.692 148.638 1.00 36.12 ? 132 MET E C   1 
ATOM 4721 O O   . MET E 1 132 ? 144.393 190.782 149.628 1.00 39.09 ? 132 MET E O   1 
ATOM 4722 C CB  . MET E 1 132 ? 143.456 189.106 147.583 1.00 38.98 ? 132 MET E CB  1 
ATOM 4723 C CG  . MET E 1 132 ? 143.154 188.133 146.453 1.00 34.61 ? 132 MET E CG  1 
ATOM 4724 S SD  . MET E 1 132 ? 141.470 187.493 146.487 1.00 52.81 ? 132 MET E SD  1 
ATOM 4725 C CE  . MET E 1 132 ? 140.545 188.938 145.982 1.00 46.16 ? 132 MET E CE  1 
ATOM 4726 N N   . LEU E 1 133 ? 146.118 191.545 148.384 1.00 34.63 ? 133 LEU E N   1 
ATOM 4727 C CA  . LEU E 1 133 ? 146.520 192.546 149.368 1.00 32.27 ? 133 LEU E CA  1 
ATOM 4728 C C   . LEU E 1 133 ? 145.374 193.496 149.695 1.00 37.58 ? 133 LEU E C   1 
ATOM 4729 O O   . LEU E 1 133 ? 145.032 193.695 150.866 1.00 43.85 ? 133 LEU E O   1 
ATOM 4730 C CB  . LEU E 1 133 ? 147.739 193.313 148.852 1.00 37.63 ? 133 LEU E CB  1 
ATOM 4731 C CG  . LEU E 1 133 ? 148.452 194.279 149.797 1.00 38.15 ? 133 LEU E CG  1 
ATOM 4732 C CD1 . LEU E 1 133 ? 149.937 194.314 149.487 1.00 40.68 ? 133 LEU E CD1 1 
ATOM 4733 C CD2 . LEU E 1 133 ? 147.861 195.669 149.663 1.00 41.94 ? 133 LEU E CD2 1 
ATOM 4734 N N   . GLY E 1 134 ? 144.771 194.093 148.672 1.00 45.07 ? 134 GLY E N   1 
ATOM 4735 C CA  . GLY E 1 134 ? 143.640 194.974 148.884 1.00 39.06 ? 134 GLY E CA  1 
ATOM 4736 C C   . GLY E 1 134 ? 142.377 194.437 148.246 1.00 43.64 ? 134 GLY E C   1 
ATOM 4737 O O   . GLY E 1 134 ? 142.259 194.415 147.018 1.00 54.53 ? 134 GLY E O   1 
ATOM 4738 N N   . SER E 1 135 ? 141.423 194.003 149.065 1.00 27.65 ? 135 SER E N   1 
ATOM 4739 C CA  . SER E 1 135 ? 140.207 193.392 148.555 1.00 34.47 ? 135 SER E CA  1 
ATOM 4740 C C   . SER E 1 135 ? 139.010 193.874 149.358 1.00 36.67 ? 135 SER E C   1 
ATOM 4741 O O   . SER E 1 135 ? 139.129 194.286 150.515 1.00 42.71 ? 135 SER E O   1 
ATOM 4742 C CB  . SER E 1 135 ? 140.286 191.860 148.596 1.00 36.98 ? 135 SER E CB  1 
ATOM 4743 O OG  . SER E 1 135 ? 139.257 191.278 147.816 1.00 39.23 ? 135 SER E OG  1 
ATOM 4744 N N   . ALA E 1 136 ? 137.845 193.820 148.717 1.00 30.93 ? 136 ALA E N   1 
ATOM 4745 C CA  . ALA E 1 136 ? 136.583 194.169 149.365 1.00 36.52 ? 136 ALA E CA  1 
ATOM 4746 C C   . ALA E 1 136 ? 135.489 193.365 148.682 1.00 37.11 ? 136 ALA E C   1 
ATOM 4747 O O   . ALA E 1 136 ? 135.126 193.658 147.539 1.00 46.08 ? 136 ALA E O   1 
ATOM 4748 C CB  . ALA E 1 136 ? 136.309 195.667 149.276 1.00 35.70 ? 136 ALA E CB  1 
ATOM 4749 N N   . MET E 1 137 ? 134.973 192.349 149.370 1.00 21.54 ? 137 MET E N   1 
ATOM 4750 C CA  . MET E 1 137 ? 133.975 191.451 148.809 1.00 27.00 ? 137 MET E CA  1 
ATOM 4751 C C   . MET E 1 137 ? 132.716 191.486 149.663 1.00 28.23 ? 137 MET E C   1 
ATOM 4752 O O   . MET E 1 137 ? 132.777 191.254 150.873 1.00 31.94 ? 137 MET E O   1 
ATOM 4753 C CB  . MET E 1 137 ? 134.518 190.023 148.715 1.00 34.69 ? 137 MET E CB  1 
ATOM 4754 C CG  . MET E 1 137 ? 135.816 189.913 147.933 1.00 36.57 ? 137 MET E CG  1 
ATOM 4755 S SD  . MET E 1 137 ? 136.802 188.478 148.402 1.00 51.85 ? 137 MET E SD  1 
ATOM 4756 C CE  . MET E 1 137 ? 135.786 187.151 147.763 1.00 38.49 ? 137 MET E CE  1 
ATOM 4757 N N   . SER E 1 138 ? 131.582 191.765 149.030 1.00 30.76 ? 138 SER E N   1 
ATOM 4758 C CA  . SER E 1 138 ? 130.298 191.822 149.715 1.00 23.74 ? 138 SER E CA  1 
ATOM 4759 C C   . SER E 1 138 ? 129.573 190.493 149.548 1.00 26.88 ? 138 SER E C   1 
ATOM 4760 O O   . SER E 1 138 ? 129.432 189.996 148.426 1.00 34.27 ? 138 SER E O   1 
ATOM 4761 C CB  . SER E 1 138 ? 129.438 192.966 149.175 1.00 21.06 ? 138 SER E CB  1 
ATOM 4762 O OG  . SER E 1 138 ? 129.095 192.751 147.819 1.00 34.67 ? 138 SER E OG  1 
ATOM 4763 N N   . ARG E 1 139 ? 129.116 189.933 150.663 1.00 23.95 ? 139 ARG E N   1 
ATOM 4764 C CA  . ARG E 1 139 ? 128.446 188.638 150.696 1.00 24.93 ? 139 ARG E CA  1 
ATOM 4765 C C   . ARG E 1 139 ? 129.230 187.543 149.965 1.00 25.46 ? 139 ARG E C   1 
ATOM 4766 O O   . ARG E 1 139 ? 128.730 186.952 149.002 1.00 24.13 ? 139 ARG E O   1 
ATOM 4767 C CB  . ARG E 1 139 ? 127.035 188.754 150.135 1.00 27.75 ? 139 ARG E CB  1 
ATOM 4768 C CG  . ARG E 1 139 ? 126.095 187.648 150.590 1.00 23.96 ? 139 ARG E CG  1 
ATOM 4769 C CD  . ARG E 1 139 ? 124.768 188.211 151.063 1.00 27.63 ? 139 ARG E CD  1 
ATOM 4770 N NE  . ARG E 1 139 ? 123.865 188.497 149.956 1.00 38.05 ? 139 ARG E NE  1 
ATOM 4771 C CZ  . ARG E 1 139 ? 122.975 187.640 149.475 1.00 36.72 ? 139 ARG E CZ  1 
ATOM 4772 N NH1 . ARG E 1 139 ? 122.848 186.423 149.977 1.00 34.68 ? 139 ARG E NH1 1 
ATOM 4773 N NH2 . ARG E 1 139 ? 122.191 188.014 148.468 1.00 24.54 ? 139 ARG E NH2 1 
ATOM 4774 N N   . PRO E 1 140 ? 130.466 187.250 150.394 1.00 30.70 ? 140 PRO E N   1 
ATOM 4775 C CA  . PRO E 1 140 ? 131.197 186.130 149.788 1.00 18.23 ? 140 PRO E CA  1 
ATOM 4776 C C   . PRO E 1 140 ? 130.833 184.810 150.446 1.00 16.25 ? 140 PRO E C   1 
ATOM 4777 O O   . PRO E 1 140 ? 131.033 184.636 151.651 1.00 19.67 ? 140 PRO E O   1 
ATOM 4778 C CB  . PRO E 1 140 ? 132.670 186.499 150.023 1.00 16.75 ? 140 PRO E CB  1 
ATOM 4779 C CG  . PRO E 1 140 ? 132.662 187.740 150.908 1.00 23.33 ? 140 PRO E CG  1 
ATOM 4780 C CD  . PRO E 1 140 ? 131.274 187.916 151.425 1.00 25.51 ? 140 PRO E CD  1 
ATOM 4781 N N   . LEU E 1 141 ? 130.301 183.872 149.666 1.00 17.64 ? 141 LEU E N   1 
ATOM 4782 C CA  . LEU E 1 141 ? 129.743 182.640 150.205 1.00 12.64 ? 141 LEU E CA  1 
ATOM 4783 C C   . LEU E 1 141 ? 130.388 181.433 149.539 1.00 15.71 ? 141 LEU E C   1 
ATOM 4784 O O   . LEU E 1 141 ? 130.475 181.368 148.310 1.00 15.27 ? 141 LEU E O   1 
ATOM 4785 C CB  . LEU E 1 141 ? 128.222 182.606 150.011 1.00 21.43 ? 141 LEU E CB  1 
ATOM 4786 C CG  . LEU E 1 141 ? 127.502 181.265 150.152 1.00 18.81 ? 141 LEU E CG  1 
ATOM 4787 C CD1 . LEU E 1 141 ? 127.752 180.647 151.512 1.00 16.87 ? 141 LEU E CD1 1 
ATOM 4788 C CD2 . LEU E 1 141 ? 126.011 181.434 149.905 1.00 22.15 ? 141 LEU E CD2 1 
ATOM 4789 N N   . ILE E 1 142 ? 130.838 180.485 150.359 1.00 21.87 ? 142 ILE E N   1 
ATOM 4790 C CA  . ILE E 1 142 ? 131.340 179.195 149.901 1.00 10.68 ? 142 ILE E CA  1 
ATOM 4791 C C   . ILE E 1 142 ? 130.628 178.111 150.698 1.00 15.07 ? 142 ILE E C   1 
ATOM 4792 O O   . ILE E 1 142 ? 130.767 178.055 151.925 1.00 28.23 ? 142 ILE E O   1 
ATOM 4793 C CB  . ILE E 1 142 ? 132.862 179.064 150.075 1.00 19.51 ? 142 ILE E CB  1 
ATOM 4794 C CG1 . ILE E 1 142 ? 133.596 180.111 149.240 1.00 30.02 ? 142 ILE E CG1 1 
ATOM 4795 C CG2 . ILE E 1 142 ? 133.323 177.662 149.705 1.00 16.66 ? 142 ILE E CG2 1 
ATOM 4796 C CD1 . ILE E 1 142 ? 135.100 179.945 149.240 1.00 17.00 ? 142 ILE E CD1 1 
ATOM 4797 N N   . HIS E 1 143 ? 129.876 177.252 150.015 1.00 11.23 ? 143 HIS E N   1 
ATOM 4798 C CA  . HIS E 1 143 ? 129.210 176.139 150.690 1.00 19.18 ? 143 HIS E CA  1 
ATOM 4799 C C   . HIS E 1 143 ? 129.232 174.909 149.795 1.00 17.52 ? 143 HIS E C   1 
ATOM 4800 O O   . HIS E 1 143 ? 128.578 174.881 148.750 1.00 24.83 ? 143 HIS E O   1 
ATOM 4801 C CB  . HIS E 1 143 ? 127.780 176.506 151.103 1.00 14.31 ? 143 HIS E CB  1 
ATOM 4802 C CG  . HIS E 1 143 ? 126.870 176.868 149.972 1.00 11.13 ? 143 HIS E CG  1 
ATOM 4803 N ND1 . HIS E 1 143 ? 126.859 178.119 149.394 1.00 28.99 ? 143 HIS E ND1 1 
ATOM 4804 C CD2 . HIS E 1 143 ? 125.903 176.156 149.344 1.00 18.83 ? 143 HIS E CD2 1 
ATOM 4805 C CE1 . HIS E 1 143 ? 125.940 178.155 148.445 1.00 19.62 ? 143 HIS E CE1 1 
ATOM 4806 N NE2 . HIS E 1 143 ? 125.348 176.977 148.394 1.00 29.50 ? 143 HIS E NE2 1 
ATOM 4807 N N   . PHE E 1 144 ? 129.977 173.887 150.213 1.00 14.58 ? 144 PHE E N   1 
ATOM 4808 C CA  . PHE E 1 144 ? 130.043 172.656 149.437 1.00 14.97 ? 144 PHE E CA  1 
ATOM 4809 C C   . PHE E 1 144 ? 128.731 171.884 149.462 1.00 7.79  ? 144 PHE E C   1 
ATOM 4810 O O   . PHE E 1 144 ? 128.473 171.099 148.545 1.00 34.64 ? 144 PHE E O   1 
ATOM 4811 C CB  . PHE E 1 144 ? 131.182 171.776 149.949 1.00 18.95 ? 144 PHE E CB  1 
ATOM 4812 C CG  . PHE E 1 144 ? 132.537 172.192 149.453 1.00 14.78 ? 144 PHE E CG  1 
ATOM 4813 C CD1 . PHE E 1 144 ? 133.145 173.337 149.940 1.00 13.58 ? 144 PHE E CD1 1 
ATOM 4814 C CD2 . PHE E 1 144 ? 133.200 171.441 148.498 1.00 15.27 ? 144 PHE E CD2 1 
ATOM 4815 C CE1 . PHE E 1 144 ? 134.389 173.723 149.485 1.00 17.23 ? 144 PHE E CE1 1 
ATOM 4816 C CE2 . PHE E 1 144 ? 134.447 171.824 148.039 1.00 15.09 ? 144 PHE E CE2 1 
ATOM 4817 C CZ  . PHE E 1 144 ? 135.041 172.967 148.533 1.00 15.67 ? 144 PHE E CZ  1 
ATOM 4818 N N   . GLY E 1 145 ? 127.897 172.096 150.473 1.00 0.00  ? 145 GLY E N   1 
ATOM 4819 C CA  . GLY E 1 145 ? 126.646 171.375 150.571 1.00 9.34  ? 145 GLY E CA  1 
ATOM 4820 C C   . GLY E 1 145 ? 125.617 171.848 149.561 1.00 16.15 ? 145 GLY E C   1 
ATOM 4821 O O   . GLY E 1 145 ? 125.776 172.858 148.874 1.00 9.66  ? 145 GLY E O   1 
ATOM 4822 N N   . ASN E 1 146 ? 124.534 171.081 149.471 1.00 20.42 ? 146 ASN E N   1 
ATOM 4823 C CA  . ASN E 1 146 ? 123.446 171.414 148.565 1.00 21.22 ? 146 ASN E CA  1 
ATOM 4824 C C   . ASN E 1 146 ? 122.746 172.692 149.012 1.00 19.80 ? 146 ASN E C   1 
ATOM 4825 O O   . ASN E 1 146 ? 122.636 172.985 150.205 1.00 22.01 ? 146 ASN E O   1 
ATOM 4826 C CB  . ASN E 1 146 ? 122.441 170.265 148.491 1.00 20.35 ? 146 ASN E CB  1 
ATOM 4827 C CG  . ASN E 1 146 ? 123.056 168.985 147.967 1.00 25.80 ? 146 ASN E CG  1 
ATOM 4828 O OD1 . ASN E 1 146 ? 123.062 168.733 146.763 1.00 25.52 ? 146 ASN E OD1 1 
ATOM 4829 N ND2 . ASN E 1 146 ? 123.578 168.165 148.873 1.00 23.77 ? 146 ASN E ND2 1 
ATOM 4830 N N   . ASP E 1 147 ? 122.267 173.457 148.034 1.00 24.50 ? 147 ASP E N   1 
ATOM 4831 C CA  . ASP E 1 147 ? 121.607 174.731 148.278 1.00 22.90 ? 147 ASP E CA  1 
ATOM 4832 C C   . ASP E 1 147 ? 120.162 174.658 147.808 1.00 18.37 ? 147 ASP E C   1 
ATOM 4833 O O   . ASP E 1 147 ? 119.892 174.223 146.684 1.00 31.21 ? 147 ASP E O   1 
ATOM 4834 C CB  . ASP E 1 147 ? 122.336 175.873 147.566 1.00 21.68 ? 147 ASP E CB  1 
ATOM 4835 C CG  . ASP E 1 147 ? 121.975 177.233 148.127 1.00 30.17 ? 147 ASP E CG  1 
ATOM 4836 O OD1 . ASP E 1 147 ? 121.335 177.285 149.198 1.00 29.97 ? 147 ASP E OD1 1 
ATOM 4837 O OD2 . ASP E 1 147 ? 122.331 178.251 147.497 1.00 38.96 ? 147 ASP E OD2 1 
ATOM 4838 N N   . TYR E 1 148 ? 119.242 175.080 148.671 1.00 19.69 ? 148 TYR E N   1 
ATOM 4839 C CA  . TYR E 1 148 ? 117.827 175.174 148.338 1.00 22.88 ? 148 TYR E CA  1 
ATOM 4840 C C   . TYR E 1 148 ? 117.332 176.562 148.710 1.00 26.71 ? 148 TYR E C   1 
ATOM 4841 O O   . TYR E 1 148 ? 117.577 177.032 149.825 1.00 23.19 ? 148 TYR E O   1 
ATOM 4842 C CB  . TYR E 1 148 ? 117.010 174.102 149.066 1.00 16.87 ? 148 TYR E CB  1 
ATOM 4843 C CG  . TYR E 1 148 ? 115.556 174.038 148.651 1.00 15.05 ? 148 TYR E CG  1 
ATOM 4844 C CD1 . TYR E 1 148 ? 114.608 174.870 149.233 1.00 19.73 ? 148 TYR E CD1 1 
ATOM 4845 C CD2 . TYR E 1 148 ? 115.131 173.145 147.677 1.00 19.74 ? 148 TYR E CD2 1 
ATOM 4846 C CE1 . TYR E 1 148 ? 113.280 174.813 148.859 1.00 22.95 ? 148 TYR E CE1 1 
ATOM 4847 C CE2 . TYR E 1 148 ? 113.804 173.077 147.299 1.00 17.95 ? 148 TYR E CE2 1 
ATOM 4848 C CZ  . TYR E 1 148 ? 112.884 173.916 147.891 1.00 19.49 ? 148 TYR E CZ  1 
ATOM 4849 O OH  . TYR E 1 148 ? 111.562 173.855 147.515 1.00 24.05 ? 148 TYR E OH  1 
ATOM 4850 N N   . GLU E 1 149 ? 116.640 177.213 147.779 1.00 31.72 ? 149 GLU E N   1 
ATOM 4851 C CA  . GLU E 1 149 ? 116.108 178.552 147.993 1.00 26.09 ? 149 GLU E CA  1 
ATOM 4852 C C   . GLU E 1 149 ? 114.670 178.609 147.504 1.00 25.67 ? 149 GLU E C   1 
ATOM 4853 O O   . GLU E 1 149 ? 114.389 178.273 146.349 1.00 34.57 ? 149 GLU E O   1 
ATOM 4854 C CB  . GLU E 1 149 ? 116.954 179.608 147.274 1.00 31.89 ? 149 GLU E CB  1 
ATOM 4855 C CG  . GLU E 1 149 ? 118.318 179.842 147.899 1.00 36.78 ? 149 GLU E CG  1 
ATOM 4856 C CD  . GLU E 1 149 ? 119.076 180.977 147.239 1.00 43.02 ? 149 GLU E CD  1 
ATOM 4857 O OE1 . GLU E 1 149 ? 118.471 181.701 146.421 1.00 35.95 ? 149 GLU E OE1 1 
ATOM 4858 O OE2 . GLU E 1 149 ? 120.277 181.145 147.537 1.00 47.50 ? 149 GLU E OE2 1 
ATOM 4859 N N   . ASP E 1 150 ? 113.765 179.034 148.385 1.00 33.18 ? 150 ASP E N   1 
ATOM 4860 C CA  . ASP E 1 150 ? 112.353 179.240 148.057 1.00 28.31 ? 150 ASP E CA  1 
ATOM 4861 C C   . ASP E 1 150 ? 112.021 180.674 148.459 1.00 30.42 ? 150 ASP E C   1 
ATOM 4862 O O   . ASP E 1 150 ? 111.573 180.927 149.580 1.00 32.11 ? 150 ASP E O   1 
ATOM 4863 C CB  . ASP E 1 150 ? 111.464 178.224 148.765 1.00 29.78 ? 150 ASP E CB  1 
ATOM 4864 C CG  . ASP E 1 150 ? 110.045 178.222 148.234 1.00 33.97 ? 150 ASP E CG  1 
ATOM 4865 O OD1 . ASP E 1 150 ? 109.799 178.860 147.189 1.00 38.41 ? 150 ASP E OD1 1 
ATOM 4866 O OD2 . ASP E 1 150 ? 109.175 177.581 148.860 1.00 38.20 ? 150 ASP E OD2 1 
ATOM 4867 N N   . ARG E 1 151 ? 112.240 181.608 147.538 1.00 35.19 ? 151 ARG E N   1 
ATOM 4868 C CA  . ARG E 1 151 ? 112.120 183.032 147.818 1.00 27.97 ? 151 ARG E CA  1 
ATOM 4869 C C   . ARG E 1 151 ? 110.798 183.567 147.284 1.00 21.74 ? 151 ARG E C   1 
ATOM 4870 O O   . ARG E 1 151 ? 110.420 183.280 146.143 1.00 20.50 ? 151 ARG E O   1 
ATOM 4871 C CB  . ARG E 1 151 ? 113.285 183.806 147.199 1.00 22.91 ? 151 ARG E CB  1 
ATOM 4872 C CG  . ARG E 1 151 ? 114.606 183.626 147.925 1.00 23.72 ? 151 ARG E CG  1 
ATOM 4873 C CD  . ARG E 1 151 ? 115.666 184.564 147.374 1.00 24.37 ? 151 ARG E CD  1 
ATOM 4874 N NE  . ARG E 1 151 ? 116.856 184.598 148.214 1.00 26.76 ? 151 ARG E NE  1 
ATOM 4875 C CZ  . ARG E 1 151 ? 117.900 185.387 148.000 1.00 28.52 ? 151 ARG E CZ  1 
ATOM 4876 N NH1 . ARG E 1 151 ? 117.936 186.224 146.975 1.00 25.66 ? 151 ARG E NH1 1 
ATOM 4877 N NH2 . ARG E 1 151 ? 118.934 185.336 148.835 1.00 30.43 ? 151 ARG E NH2 1 
ATOM 4878 N N   . TYR E 1 152 ? 110.100 184.341 148.115 1.00 25.76 ? 152 TYR E N   1 
ATOM 4879 C CA  . TYR E 1 152 ? 108.871 185.036 147.736 1.00 21.78 ? 152 TYR E CA  1 
ATOM 4880 C C   . TYR E 1 152 ? 109.040 186.484 148.191 1.00 23.68 ? 152 TYR E C   1 
ATOM 4881 O O   . TYR E 1 152 ? 108.708 186.832 149.327 1.00 26.45 ? 152 TYR E O   1 
ATOM 4882 C CB  . TYR E 1 152 ? 107.640 184.372 148.355 1.00 17.43 ? 152 TYR E CB  1 
ATOM 4883 C CG  . TYR E 1 152 ? 106.318 185.045 148.038 1.00 23.10 ? 152 TYR E CG  1 
ATOM 4884 C CD1 . TYR E 1 152 ? 106.195 185.934 146.977 1.00 24.33 ? 152 TYR E CD1 1 
ATOM 4885 C CD2 . TYR E 1 152 ? 105.187 184.782 148.799 1.00 27.63 ? 152 TYR E CD2 1 
ATOM 4886 C CE1 . TYR E 1 152 ? 104.991 186.548 146.693 1.00 25.11 ? 152 TYR E CE1 1 
ATOM 4887 C CE2 . TYR E 1 152 ? 103.977 185.389 148.520 1.00 23.82 ? 152 TYR E CE2 1 
ATOM 4888 C CZ  . TYR E 1 152 ? 103.884 186.270 147.466 1.00 24.64 ? 152 TYR E CZ  1 
ATOM 4889 O OH  . TYR E 1 152 ? 102.682 186.876 147.184 1.00 29.62 ? 152 TYR E OH  1 
ATOM 4890 N N   . TYR E 1 153 ? 109.557 187.322 147.298 1.00 30.47 ? 153 TYR E N   1 
ATOM 4891 C CA  . TYR E 1 153 ? 109.806 188.728 147.583 1.00 26.34 ? 153 TYR E CA  1 
ATOM 4892 C C   . TYR E 1 153 ? 108.685 189.558 146.970 1.00 24.83 ? 153 TYR E C   1 
ATOM 4893 O O   . TYR E 1 153 ? 108.421 189.456 145.767 1.00 30.00 ? 153 TYR E O   1 
ATOM 4894 C CB  . TYR E 1 153 ? 111.162 189.168 147.029 1.00 22.54 ? 153 TYR E CB  1 
ATOM 4895 C CG  . TYR E 1 153 ? 112.361 188.688 147.822 1.00 22.15 ? 153 TYR E CG  1 
ATOM 4896 C CD1 . TYR E 1 153 ? 112.243 187.672 148.762 1.00 25.79 ? 153 TYR E CD1 1 
ATOM 4897 C CD2 . TYR E 1 153 ? 113.613 189.252 147.624 1.00 21.51 ? 153 TYR E CD2 1 
ATOM 4898 C CE1 . TYR E 1 153 ? 113.337 187.234 149.482 1.00 26.52 ? 153 TYR E CE1 1 
ATOM 4899 C CE2 . TYR E 1 153 ? 114.713 188.820 148.339 1.00 22.34 ? 153 TYR E CE2 1 
ATOM 4900 C CZ  . TYR E 1 153 ? 114.570 187.812 149.266 1.00 24.14 ? 153 TYR E CZ  1 
ATOM 4901 O OH  . TYR E 1 153 ? 115.664 187.381 149.979 1.00 30.74 ? 153 TYR E OH  1 
ATOM 4902 N N   . ARG E 1 154 ? 108.030 190.374 147.793 1.00 33.17 ? 154 ARG E N   1 
ATOM 4903 C CA  . ARG E 1 154 ? 106.911 191.193 147.341 1.00 29.35 ? 154 ARG E CA  1 
ATOM 4904 C C   . ARG E 1 154 ? 107.063 192.599 147.895 1.00 32.92 ? 154 ARG E C   1 
ATOM 4905 O O   . ARG E 1 154 ? 107.122 192.783 149.115 1.00 30.84 ? 154 ARG E O   1 
ATOM 4906 C CB  . ARG E 1 154 ? 105.572 190.589 147.775 1.00 26.79 ? 154 ARG E CB  1 
ATOM 4907 C CG  . ARG E 1 154 ? 104.361 191.379 147.310 1.00 35.23 ? 154 ARG E CG  1 
ATOM 4908 C CD  . ARG E 1 154 ? 103.069 190.745 147.794 1.00 38.18 ? 154 ARG E CD  1 
ATOM 4909 N NE  . ARG E 1 154 ? 101.895 191.445 147.287 1.00 41.54 ? 154 ARG E NE  1 
ATOM 4910 C CZ  . ARG E 1 154 ? 100.644 191.076 147.521 1.00 43.21 ? 154 ARG E CZ  1 
ATOM 4911 N NH1 . ARG E 1 154 ? 100.364 190.012 148.256 1.00 41.26 ? 154 ARG E NH1 1 
ATOM 4912 N NH2 . ARG E 1 154 ? 99.648  191.792 147.006 1.00 38.29 ? 154 ARG E NH2 1 
ATOM 4913 N N   . GLU E 1 155 ? 107.122 193.585 146.997 1.00 40.15 ? 155 GLU E N   1 
ATOM 4914 C CA  . GLU E 1 155 ? 107.157 195.003 147.363 1.00 35.54 ? 155 GLU E CA  1 
ATOM 4915 C C   . GLU E 1 155 ? 108.327 195.320 148.292 1.00 34.27 ? 155 GLU E C   1 
ATOM 4916 O O   . GLU E 1 155 ? 108.206 196.125 149.217 1.00 37.52 ? 155 GLU E O   1 
ATOM 4917 C CB  . GLU E 1 155 ? 105.832 195.442 147.989 1.00 35.18 ? 155 GLU E CB  1 
ATOM 4918 C CG  . GLU E 1 155 ? 104.657 195.432 147.025 1.00 37.54 ? 155 GLU E CG  1 
ATOM 4919 C CD  . GLU E 1 155 ? 103.321 195.530 147.733 1.00 43.67 ? 155 GLU E CD  1 
ATOM 4920 O OE1 . GLU E 1 155 ? 103.123 194.810 148.734 1.00 43.82 ? 155 GLU E OE1 1 
ATOM 4921 O OE2 . GLU E 1 155 ? 102.469 196.328 147.290 1.00 40.89 ? 155 GLU E OE2 1 
ATOM 4922 N N   . ASN E 1 156 ? 109.470 194.694 148.039 1.00 28.51 ? 156 ASN E N   1 
ATOM 4923 C CA  . ASN E 1 156 ? 110.672 194.909 148.835 1.00 29.54 ? 156 ASN E CA  1 
ATOM 4924 C C   . ASN E 1 156 ? 111.567 195.925 148.137 1.00 30.86 ? 156 ASN E C   1 
ATOM 4925 O O   . ASN E 1 156 ? 111.868 195.782 146.948 1.00 40.39 ? 156 ASN E O   1 
ATOM 4926 C CB  . ASN E 1 156 ? 111.426 193.599 149.053 1.00 31.36 ? 156 ASN E CB  1 
ATOM 4927 C CG  . ASN E 1 156 ? 110.556 192.525 149.674 1.00 30.47 ? 156 ASN E CG  1 
ATOM 4928 O OD1 . ASN E 1 156 ? 109.964 191.707 148.970 1.00 38.20 ? 156 ASN E OD1 1 
ATOM 4929 N ND2 . ASN E 1 156 ? 110.470 192.526 150.998 1.00 35.25 ? 156 ASN E ND2 1 
ATOM 4930 N N   . MET E 1 157 ? 111.986 196.946 148.879 1.00 36.16 ? 157 MET E N   1 
ATOM 4931 C CA  . MET E 1 157 ? 112.830 198.015 148.350 1.00 38.76 ? 157 MET E CA  1 
ATOM 4932 C C   . MET E 1 157 ? 114.273 197.723 148.746 1.00 37.37 ? 157 MET E C   1 
ATOM 4933 O O   . MET E 1 157 ? 114.667 197.928 149.898 1.00 41.20 ? 157 MET E O   1 
ATOM 4934 C CB  . MET E 1 157 ? 112.370 199.374 148.866 1.00 36.94 ? 157 MET E CB  1 
ATOM 4935 C CG  . MET E 1 157 ? 112.493 200.498 147.849 1.00 39.70 ? 157 MET E CG  1 
ATOM 4936 S SD  . MET E 1 157 ? 114.205 200.953 147.511 1.00 53.93 ? 157 MET E SD  1 
ATOM 4937 C CE  . MET E 1 157 ? 114.486 202.183 148.781 1.00 40.79 ? 157 MET E CE  1 
ATOM 4938 N N   . TYR E 1 158 ? 115.060 197.244 147.788 1.00 32.10 ? 158 TYR E N   1 
ATOM 4939 C CA  . TYR E 1 158 ? 116.473 196.946 148.000 1.00 23.33 ? 158 TYR E CA  1 
ATOM 4940 C C   . TYR E 1 158 ? 117.288 198.092 147.413 1.00 30.62 ? 158 TYR E C   1 
ATOM 4941 O O   . TYR E 1 158 ? 117.436 198.204 146.194 1.00 40.92 ? 158 TYR E O   1 
ATOM 4942 C CB  . TYR E 1 158 ? 116.847 195.612 147.363 1.00 31.67 ? 158 TYR E CB  1 
ATOM 4943 C CG  . TYR E 1 158 ? 116.525 194.412 148.225 1.00 28.88 ? 158 TYR E CG  1 
ATOM 4944 C CD1 . TYR E 1 158 ? 117.454 193.913 149.127 1.00 26.36 ? 158 TYR E CD1 1 
ATOM 4945 C CD2 . TYR E 1 158 ? 115.292 193.780 148.135 1.00 24.65 ? 158 TYR E CD2 1 
ATOM 4946 C CE1 . TYR E 1 158 ? 117.164 192.818 149.916 1.00 28.95 ? 158 TYR E CE1 1 
ATOM 4947 C CE2 . TYR E 1 158 ? 114.993 192.684 148.920 1.00 26.22 ? 158 TYR E CE2 1 
ATOM 4948 C CZ  . TYR E 1 158 ? 115.933 192.208 149.808 1.00 31.59 ? 158 TYR E CZ  1 
ATOM 4949 O OH  . TYR E 1 158 ? 115.642 191.117 150.592 1.00 31.35 ? 158 TYR E OH  1 
ATOM 4950 N N   . ARG E 1 159 ? 117.819 198.945 148.285 1.00 31.91 ? 159 ARG E N   1 
ATOM 4951 C CA  . ARG E 1 159 ? 118.614 200.097 147.876 1.00 31.02 ? 159 ARG E CA  1 
ATOM 4952 C C   . ARG E 1 159 ? 120.089 199.761 148.063 1.00 34.81 ? 159 ARG E C   1 
ATOM 4953 O O   . ARG E 1 159 ? 120.573 199.676 149.196 1.00 38.90 ? 159 ARG E O   1 
ATOM 4954 C CB  . ARG E 1 159 ? 118.225 201.338 148.675 1.00 34.09 ? 159 ARG E CB  1 
ATOM 4955 C CG  . ARG E 1 159 ? 118.627 202.645 148.014 1.00 35.39 ? 159 ARG E CG  1 
ATOM 4956 C CD  . ARG E 1 159 ? 118.006 203.837 148.720 1.00 31.48 ? 159 ARG E CD  1 
ATOM 4957 N NE  . ARG E 1 159 ? 118.072 205.045 147.907 1.00 35.04 ? 159 ARG E NE  1 
ATOM 4958 C CZ  . ARG E 1 159 ? 117.179 205.377 146.985 1.00 39.92 ? 159 ARG E CZ  1 
ATOM 4959 N NH1 . ARG E 1 159 ? 116.128 204.613 146.733 1.00 39.44 ? 159 ARG E NH1 1 
ATOM 4960 N NH2 . ARG E 1 159 ? 117.341 206.505 146.299 1.00 35.94 ? 159 ARG E NH2 1 
ATOM 4961 N N   . TYR E 1 160 ? 120.794 199.578 146.951 1.00 20.38 ? 160 TYR E N   1 
ATOM 4962 C CA  . TYR E 1 160 ? 122.214 199.243 146.945 1.00 21.14 ? 160 TYR E CA  1 
ATOM 4963 C C   . TYR E 1 160 ? 122.551 198.030 147.818 1.00 24.15 ? 160 TYR E C   1 
ATOM 4964 O O   . TYR E 1 160 ? 123.353 198.135 148.752 1.00 29.58 ? 160 TYR E O   1 
ATOM 4965 C CB  . TYR E 1 160 ? 123.044 200.448 147.366 1.00 25.04 ? 160 TYR E CB  1 
ATOM 4966 C CG  . TYR E 1 160 ? 123.077 201.571 146.353 1.00 28.24 ? 160 TYR E CG  1 
ATOM 4967 C CD1 . TYR E 1 160 ? 121.999 202.435 146.207 1.00 28.18 ? 160 TYR E CD1 1 
ATOM 4968 C CD2 . TYR E 1 160 ? 124.190 201.774 145.548 1.00 30.07 ? 160 TYR E CD2 1 
ATOM 4969 C CE1 . TYR E 1 160 ? 122.027 203.464 145.285 1.00 26.68 ? 160 TYR E CE1 1 
ATOM 4970 C CE2 . TYR E 1 160 ? 124.228 202.800 144.624 1.00 26.95 ? 160 TYR E CE2 1 
ATOM 4971 C CZ  . TYR E 1 160 ? 123.144 203.641 144.495 1.00 25.00 ? 160 TYR E CZ  1 
ATOM 4972 O OH  . TYR E 1 160 ? 123.176 204.664 143.577 1.00 31.55 ? 160 TYR E OH  1 
ATOM 4973 N N   . PRO E 1 161 ? 121.962 196.864 147.543 1.00 20.42 ? 161 PRO E N   1 
ATOM 4974 C CA  . PRO E 1 161 ? 122.341 195.664 148.297 1.00 18.89 ? 161 PRO E CA  1 
ATOM 4975 C C   . PRO E 1 161 ? 123.649 195.070 147.800 1.00 21.09 ? 161 PRO E C   1 
ATOM 4976 O O   . PRO E 1 161 ? 123.927 195.043 146.598 1.00 24.28 ? 161 PRO E O   1 
ATOM 4977 C CB  . PRO E 1 161 ? 121.163 194.713 148.059 1.00 13.88 ? 161 PRO E CB  1 
ATOM 4978 C CG  . PRO E 1 161 ? 120.646 195.096 146.734 1.00 20.22 ? 161 PRO E CG  1 
ATOM 4979 C CD  . PRO E 1 161 ? 120.908 196.573 146.553 1.00 19.05 ? 161 PRO E CD  1 
ATOM 4980 N N   . ASN E 1 162 ? 124.451 194.589 148.752 1.00 20.79 ? 162 ASN E N   1 
ATOM 4981 C CA  . ASN E 1 162 ? 125.768 194.014 148.469 1.00 15.77 ? 162 ASN E CA  1 
ATOM 4982 C C   . ASN E 1 162 ? 126.642 194.995 147.693 1.00 15.47 ? 162 ASN E C   1 
ATOM 4983 O O   . ASN E 1 162 ? 127.359 194.624 146.761 1.00 27.93 ? 162 ASN E O   1 
ATOM 4984 C CB  . ASN E 1 162 ? 125.641 192.684 147.726 1.00 19.21 ? 162 ASN E CB  1 
ATOM 4985 C CG  . ASN E 1 162 ? 124.736 191.700 148.441 1.00 23.01 ? 162 ASN E CG  1 
ATOM 4986 O OD1 . ASN E 1 162 ? 124.958 191.366 149.603 1.00 23.24 ? 162 ASN E OD1 1 
ATOM 4987 N ND2 . ASN E 1 162 ? 123.707 191.229 147.746 1.00 28.10 ? 162 ASN E ND2 1 
ATOM 4988 N N   . GLN E 1 163 ? 126.580 196.265 148.084 1.00 19.47 ? 163 GLN E N   1 
ATOM 4989 C CA  . GLN E 1 163 ? 127.345 197.307 147.416 1.00 23.52 ? 163 GLN E CA  1 
ATOM 4990 C C   . GLN E 1 163 ? 128.784 197.307 147.914 1.00 28.33 ? 163 GLN E C   1 
ATOM 4991 O O   . GLN E 1 163 ? 129.034 197.242 149.122 1.00 32.85 ? 163 GLN E O   1 
ATOM 4992 C CB  . GLN E 1 163 ? 126.700 198.673 147.652 1.00 17.53 ? 163 GLN E CB  1 
ATOM 4993 C CG  . GLN E 1 163 ? 126.982 199.690 146.560 1.00 25.39 ? 163 GLN E CG  1 
ATOM 4994 C CD  . GLN E 1 163 ? 128.052 200.688 146.954 1.00 28.85 ? 163 GLN E CD  1 
ATOM 4995 O OE1 . GLN E 1 163 ? 128.690 200.550 147.998 1.00 29.13 ? 163 GLN E OE1 1 
ATOM 4996 N NE2 . GLN E 1 163 ? 128.253 201.699 146.120 1.00 31.23 ? 163 GLN E NE2 1 
ATOM 4997 N N   . VAL E 1 164 ? 129.728 197.377 146.982 1.00 28.26 ? 164 VAL E N   1 
ATOM 4998 C CA  . VAL E 1 164 ? 131.150 197.423 147.294 1.00 21.81 ? 164 VAL E CA  1 
ATOM 4999 C C   . VAL E 1 164 ? 131.643 198.816 146.929 1.00 29.00 ? 164 VAL E C   1 
ATOM 5000 O O   . VAL E 1 164 ? 131.974 199.087 145.769 1.00 32.82 ? 164 VAL E O   1 
ATOM 5001 C CB  . VAL E 1 164 ? 131.939 196.339 146.552 1.00 31.55 ? 164 VAL E CB  1 
ATOM 5002 C CG1 . VAL E 1 164 ? 133.385 196.326 147.022 1.00 23.51 ? 164 VAL E CG1 1 
ATOM 5003 C CG2 . VAL E 1 164 ? 131.295 194.978 146.757 1.00 30.10 ? 164 VAL E CG2 1 
ATOM 5004 N N   . TYR E 1 165 ? 131.696 199.709 147.917 1.00 34.19 ? 165 TYR E N   1 
ATOM 5005 C CA  . TYR E 1 165 ? 132.211 201.061 147.709 1.00 28.28 ? 165 TYR E CA  1 
ATOM 5006 C C   . TYR E 1 165 ? 133.723 201.026 147.912 1.00 33.76 ? 165 TYR E C   1 
ATOM 5007 O O   . TYR E 1 165 ? 134.254 201.350 148.976 1.00 40.58 ? 165 TYR E O   1 
ATOM 5008 C CB  . TYR E 1 165 ? 131.529 202.051 148.646 1.00 29.51 ? 165 TYR E CB  1 
ATOM 5009 C CG  . TYR E 1 165 ? 131.446 203.452 148.089 1.00 33.82 ? 165 TYR E CG  1 
ATOM 5010 C CD1 . TYR E 1 165 ? 130.401 203.828 147.256 1.00 33.51 ? 165 TYR E CD1 1 
ATOM 5011 C CD2 . TYR E 1 165 ? 132.416 204.399 148.390 1.00 33.01 ? 165 TYR E CD2 1 
ATOM 5012 C CE1 . TYR E 1 165 ? 130.322 205.108 146.742 1.00 32.79 ? 165 TYR E CE1 1 
ATOM 5013 C CE2 . TYR E 1 165 ? 132.346 205.681 147.880 1.00 29.38 ? 165 TYR E CE2 1 
ATOM 5014 C CZ  . TYR E 1 165 ? 131.297 206.030 147.057 1.00 29.63 ? 165 TYR E CZ  1 
ATOM 5015 O OH  . TYR E 1 165 ? 131.222 207.307 146.548 1.00 33.49 ? 165 TYR E OH  1 
ATOM 5016 N N   . TYR E 1 166 ? 134.423 200.619 146.855 1.00 32.05 ? 166 TYR E N   1 
ATOM 5017 C CA  . TYR E 1 166 ? 135.875 200.452 146.890 1.00 29.32 ? 166 TYR E CA  1 
ATOM 5018 C C   . TYR E 1 166 ? 136.510 201.766 146.456 1.00 34.30 ? 166 TYR E C   1 
ATOM 5019 O O   . TYR E 1 166 ? 136.709 202.024 145.268 1.00 41.73 ? 166 TYR E O   1 
ATOM 5020 C CB  . TYR E 1 166 ? 136.300 199.295 145.994 1.00 26.97 ? 166 TYR E CB  1 
ATOM 5021 C CG  . TYR E 1 166 ? 137.746 198.883 146.153 1.00 34.77 ? 166 TYR E CG  1 
ATOM 5022 C CD1 . TYR E 1 166 ? 138.128 197.993 147.147 1.00 32.51 ? 166 TYR E CD1 1 
ATOM 5023 C CD2 . TYR E 1 166 ? 138.729 199.384 145.311 1.00 32.02 ? 166 TYR E CD2 1 
ATOM 5024 C CE1 . TYR E 1 166 ? 139.447 197.611 147.295 1.00 34.92 ? 166 TYR E CE1 1 
ATOM 5025 C CE2 . TYR E 1 166 ? 140.051 199.010 145.453 1.00 31.55 ? 166 TYR E CE2 1 
ATOM 5026 C CZ  . TYR E 1 166 ? 140.404 198.124 146.448 1.00 35.62 ? 166 TYR E CZ  1 
ATOM 5027 O OH  . TYR E 1 166 ? 141.719 197.748 146.594 1.00 38.33 ? 166 TYR E OH  1 
ATOM 5028 N N   . ARG E 1 167 ? 136.834 202.611 147.433 1.00 33.37 ? 167 ARG E N   1 
ATOM 5029 C CA  . ARG E 1 167 ? 137.414 203.932 147.185 1.00 38.24 ? 167 ARG E CA  1 
ATOM 5030 C C   . ARG E 1 167 ? 138.639 204.137 148.071 1.00 40.68 ? 167 ARG E C   1 
ATOM 5031 O O   . ARG E 1 167 ? 138.608 204.927 149.022 1.00 37.52 ? 167 ARG E O   1 
ATOM 5032 C CB  . ARG E 1 167 ? 136.374 205.028 147.425 1.00 30.11 ? 167 ARG E CB  1 
ATOM 5033 C CG  . ARG E 1 167 ? 136.786 206.419 146.963 1.00 30.04 ? 167 ARG E CG  1 
ATOM 5034 C CD  . ARG E 1 167 ? 136.181 206.759 145.618 1.00 39.27 ? 167 ARG E CD  1 
ATOM 5035 N NE  . ARG E 1 167 ? 136.469 208.131 145.217 1.00 36.94 ? 167 ARG E NE  1 
ATOM 5036 C CZ  . ARG E 1 167 ? 135.583 209.117 145.232 1.00 38.27 ? 167 ARG E CZ  1 
ATOM 5037 N NH1 . ARG E 1 167 ? 134.334 208.918 145.622 1.00 41.74 ? 167 ARG E NH1 1 
ATOM 5038 N NH2 . ARG E 1 167 ? 135.958 210.332 144.846 1.00 39.05 ? 167 ARG E NH2 1 
ATOM 5039 N N   . PRO E 1 168 ? 139.738 203.436 147.791 1.00 38.42 ? 168 PRO E N   1 
ATOM 5040 C CA  . PRO E 1 168 ? 140.972 203.682 148.545 1.00 30.85 ? 168 PRO E CA  1 
ATOM 5041 C C   . PRO E 1 168 ? 141.679 204.943 148.076 1.00 33.12 ? 168 PRO E C   1 
ATOM 5042 O O   . PRO E 1 168 ? 141.709 205.259 146.884 1.00 38.90 ? 168 PRO E O   1 
ATOM 5043 C CB  . PRO E 1 168 ? 141.815 202.433 148.262 1.00 30.80 ? 168 PRO E CB  1 
ATOM 5044 C CG  . PRO E 1 168 ? 141.348 201.968 146.944 1.00 31.95 ? 168 PRO E CG  1 
ATOM 5045 C CD  . PRO E 1 168 ? 139.884 202.302 146.861 1.00 31.88 ? 168 PRO E CD  1 
ATOM 5046 N N   . VAL E 1 169 ? 142.251 205.668 149.035 1.00 37.48 ? 169 VAL E N   1 
ATOM 5047 C CA  . VAL E 1 169 ? 143.007 206.885 148.767 1.00 38.75 ? 169 VAL E CA  1 
ATOM 5048 C C   . VAL E 1 169 ? 144.365 206.767 149.446 1.00 42.93 ? 169 VAL E C   1 
ATOM 5049 O O   . VAL E 1 169 ? 144.436 206.502 150.651 1.00 42.92 ? 169 VAL E O   1 
ATOM 5050 C CB  . VAL E 1 169 ? 142.267 208.144 149.258 1.00 30.52 ? 169 VAL E CB  1 
ATOM 5051 C CG1 . VAL E 1 169 ? 143.069 209.392 148.925 1.00 34.99 ? 169 VAL E CG1 1 
ATOM 5052 C CG2 . VAL E 1 169 ? 140.876 208.220 148.647 1.00 31.16 ? 169 VAL E CG2 1 
ATOM 5053 N N   . ASP E 1 170 ? 145.433 206.967 148.673 1.00 34.93 ? 170 ASP E N   1 
ATOM 5054 C CA  . ASP E 1 170 ? 146.803 206.971 149.187 1.00 29.56 ? 170 ASP E CA  1 
ATOM 5055 C C   . ASP E 1 170 ? 147.117 205.686 149.953 1.00 30.61 ? 170 ASP E C   1 
ATOM 5056 O O   . ASP E 1 170 ? 147.668 205.705 151.055 1.00 34.97 ? 170 ASP E O   1 
ATOM 5057 C CB  . ASP E 1 170 ? 147.054 208.201 150.060 1.00 34.32 ? 170 ASP E CB  1 
ATOM 5058 C CG  . ASP E 1 170 ? 146.781 209.500 149.330 1.00 38.06 ? 170 ASP E CG  1 
ATOM 5059 O OD1 . ASP E 1 170 ? 146.437 209.451 148.132 1.00 42.49 ? 170 ASP E OD1 1 
ATOM 5060 O OD2 . ASP E 1 170 ? 146.912 210.574 149.955 1.00 39.16 ? 170 ASP E OD2 1 
ATOM 5061 N N   . GLN E 1 171 ? 146.756 204.555 149.354 1.00 33.72 ? 171 GLN E N   1 
ATOM 5062 C CA  . GLN E 1 171 ? 146.994 203.251 149.966 1.00 34.83 ? 171 GLN E CA  1 
ATOM 5063 C C   . GLN E 1 171 ? 148.423 202.822 149.655 1.00 33.08 ? 171 GLN E C   1 
ATOM 5064 O O   . GLN E 1 171 ? 148.756 202.540 148.500 1.00 30.74 ? 171 GLN E O   1 
ATOM 5065 C CB  . GLN E 1 171 ? 145.980 202.232 149.453 1.00 25.75 ? 171 GLN E CB  1 
ATOM 5066 C CG  . GLN E 1 171 ? 145.619 201.151 150.457 1.00 28.18 ? 171 GLN E CG  1 
ATOM 5067 C CD  . GLN E 1 171 ? 144.572 200.191 149.927 1.00 28.61 ? 171 GLN E CD  1 
ATOM 5068 O OE1 . GLN E 1 171 ? 144.419 200.029 148.716 1.00 34.46 ? 171 GLN E OE1 1 
ATOM 5069 N NE2 . GLN E 1 171 ? 143.844 199.547 150.831 1.00 23.06 ? 171 GLN E NE2 1 
ATOM 5070 N N   . TYR E 1 172 ? 149.271 202.775 150.682 1.00 33.45 ? 172 TYR E N   1 
ATOM 5071 C CA  . TYR E 1 172 ? 150.670 202.367 150.552 1.00 29.28 ? 172 TYR E CA  1 
ATOM 5072 C C   . TYR E 1 172 ? 150.884 201.155 151.451 1.00 35.69 ? 172 TYR E C   1 
ATOM 5073 O O   . TYR E 1 172 ? 151.355 201.281 152.582 1.00 42.15 ? 172 TYR E O   1 
ATOM 5074 C CB  . TYR E 1 172 ? 151.626 203.517 150.921 1.00 34.16 ? 172 TYR E CB  1 
ATOM 5075 C CG  . TYR E 1 172 ? 151.635 204.677 149.952 1.00 33.89 ? 172 TYR E CG  1 
ATOM 5076 C CD1 . TYR E 1 172 ? 150.593 205.594 149.923 1.00 29.80 ? 172 TYR E CD1 1 
ATOM 5077 C CD2 . TYR E 1 172 ? 152.698 204.868 149.078 1.00 35.67 ? 172 TYR E CD2 1 
ATOM 5078 C CE1 . TYR E 1 172 ? 150.601 206.658 149.042 1.00 32.75 ? 172 TYR E CE1 1 
ATOM 5079 C CE2 . TYR E 1 172 ? 152.716 205.931 148.196 1.00 37.83 ? 172 TYR E CE2 1 
ATOM 5080 C CZ  . TYR E 1 172 ? 151.664 206.822 148.181 1.00 40.65 ? 172 TYR E CZ  1 
ATOM 5081 O OH  . TYR E 1 172 ? 151.678 207.882 147.304 1.00 44.24 ? 172 TYR E OH  1 
ATOM 5082 N N   . ASN E 1 173 ? 150.568 199.972 150.935 1.00 27.02 ? 173 ASN E N   1 
ATOM 5083 C CA  . ASN E 1 173 ? 150.653 198.740 151.708 1.00 23.51 ? 173 ASN E CA  1 
ATOM 5084 C C   . ASN E 1 173 ? 151.677 197.804 151.082 1.00 31.96 ? 173 ASN E C   1 
ATOM 5085 O O   . ASN E 1 173 ? 151.815 197.748 149.856 1.00 35.72 ? 173 ASN E O   1 
ATOM 5086 C CB  . ASN E 1 173 ? 149.293 198.045 151.796 1.00 22.96 ? 173 ASN E CB  1 
ATOM 5087 C CG  . ASN E 1 173 ? 148.289 198.830 152.614 1.00 32.44 ? 173 ASN E CG  1 
ATOM 5088 O OD1 . ASN E 1 173 ? 148.660 199.628 153.474 1.00 38.15 ? 173 ASN E OD1 1 
ATOM 5089 N ND2 . ASN E 1 173 ? 147.007 198.608 152.348 1.00 32.79 ? 173 ASN E ND2 1 
ATOM 5090 N N   . ASN E 1 174 ? 152.391 197.071 151.934 1.00 30.72 ? 174 ASN E N   1 
ATOM 5091 C CA  . ASN E 1 174 ? 153.440 196.156 151.500 1.00 20.94 ? 174 ASN E CA  1 
ATOM 5092 C C   . ASN E 1 174 ? 153.225 194.803 152.157 1.00 25.58 ? 174 ASN E C   1 
ATOM 5093 O O   . ASN E 1 174 ? 153.278 194.691 153.386 1.00 36.65 ? 174 ASN E O   1 
ATOM 5094 C CB  . ASN E 1 174 ? 154.827 196.704 151.848 1.00 19.07 ? 174 ASN E CB  1 
ATOM 5095 C CG  . ASN E 1 174 ? 155.226 197.875 150.975 1.00 30.17 ? 174 ASN E CG  1 
ATOM 5096 O OD1 . ASN E 1 174 ? 154.825 199.012 151.222 1.00 38.76 ? 174 ASN E OD1 1 
ATOM 5097 N ND2 . ASN E 1 174 ? 156.025 197.605 149.949 1.00 26.67 ? 174 ASN E ND2 1 
ATOM 5098 N N   . GLN E 1 175 ? 152.982 193.779 151.339 1.00 29.57 ? 175 GLN E N   1 
ATOM 5099 C CA  . GLN E 1 175 ? 152.906 192.389 151.790 1.00 30.86 ? 175 GLN E CA  1 
ATOM 5100 C C   . GLN E 1 175 ? 153.826 191.590 150.871 1.00 29.89 ? 175 GLN E C   1 
ATOM 5101 O O   . GLN E 1 175 ? 153.379 191.011 149.879 1.00 29.59 ? 175 GLN E O   1 
ATOM 5102 C CB  . GLN E 1 175 ? 151.473 191.867 151.761 1.00 22.86 ? 175 GLN E CB  1 
ATOM 5103 C CG  . GLN E 1 175 ? 151.289 190.525 152.448 1.00 24.78 ? 175 GLN E CG  1 
ATOM 5104 C CD  . GLN E 1 175 ? 149.830 190.149 152.612 1.00 26.54 ? 175 GLN E CD  1 
ATOM 5105 O OE1 . GLN E 1 175 ? 148.984 190.533 151.805 1.00 33.43 ? 175 GLN E OE1 1 
ATOM 5106 N NE2 . GLN E 1 175 ? 149.529 189.396 153.662 1.00 27.21 ? 175 GLN E NE2 1 
ATOM 5107 N N   . ASN E 1 176 ? 155.111 191.555 151.210 1.00 26.95 ? 176 ASN E N   1 
ATOM 5108 C CA  . ASN E 1 176 ? 156.131 190.980 150.348 1.00 26.18 ? 176 ASN E CA  1 
ATOM 5109 C C   . ASN E 1 176 ? 156.831 189.825 151.049 1.00 30.01 ? 176 ASN E C   1 
ATOM 5110 O O   . ASN E 1 176 ? 157.014 189.832 152.269 1.00 30.20 ? 176 ASN E O   1 
ATOM 5111 C CB  . ASN E 1 176 ? 157.164 192.035 149.936 1.00 32.05 ? 176 ASN E CB  1 
ATOM 5112 C CG  . ASN E 1 176 ? 156.529 193.257 149.305 1.00 34.20 ? 176 ASN E CG  1 
ATOM 5113 O OD1 . ASN E 1 176 ? 155.576 193.146 148.534 1.00 35.76 ? 176 ASN E OD1 1 
ATOM 5114 N ND2 . ASN E 1 176 ? 157.053 194.432 149.631 1.00 35.64 ? 176 ASN E ND2 1 
ATOM 5115 N N   . THR E 1 177 ? 157.225 188.831 150.258 1.00 40.26 ? 177 THR E N   1 
ATOM 5116 C CA  . THR E 1 177 ? 157.986 187.687 150.739 1.00 36.19 ? 177 THR E CA  1 
ATOM 5117 C C   . THR E 1 177 ? 159.420 187.816 150.243 1.00 30.76 ? 177 THR E C   1 
ATOM 5118 O O   . THR E 1 177 ? 159.657 187.882 149.031 1.00 36.74 ? 177 THR E O   1 
ATOM 5119 C CB  . THR E 1 177 ? 157.370 186.373 150.261 1.00 32.36 ? 177 THR E CB  1 
ATOM 5120 O OG1 . THR E 1 177 ? 156.042 186.246 150.785 1.00 28.76 ? 177 THR E OG1 1 
ATOM 5121 C CG2 . THR E 1 177 ? 158.210 185.196 150.725 1.00 33.83 ? 177 THR E CG2 1 
ATOM 5122 N N   . PHE E 1 178 ? 160.367 187.854 151.175 1.00 28.92 ? 178 PHE E N   1 
ATOM 5123 C CA  . PHE E 1 178 ? 161.782 187.992 150.855 1.00 29.69 ? 178 PHE E CA  1 
ATOM 5124 C C   . PHE E 1 178 ? 162.513 186.740 151.314 1.00 34.55 ? 178 PHE E C   1 
ATOM 5125 O O   . PHE E 1 178 ? 162.455 186.380 152.494 1.00 39.63 ? 178 PHE E O   1 
ATOM 5126 C CB  . PHE E 1 178 ? 162.377 189.236 151.519 1.00 30.28 ? 178 PHE E CB  1 
ATOM 5127 C CG  . PHE E 1 178 ? 162.225 190.488 150.705 1.00 33.96 ? 178 PHE E CG  1 
ATOM 5128 C CD1 . PHE E 1 178 ? 161.078 191.258 150.804 1.00 33.69 ? 178 PHE E CD1 1 
ATOM 5129 C CD2 . PHE E 1 178 ? 163.228 190.894 149.843 1.00 36.35 ? 178 PHE E CD2 1 
ATOM 5130 C CE1 . PHE E 1 178 ? 160.936 192.411 150.055 1.00 35.22 ? 178 PHE E CE1 1 
ATOM 5131 C CE2 . PHE E 1 178 ? 163.092 192.047 149.092 1.00 38.84 ? 178 PHE E CE2 1 
ATOM 5132 C CZ  . PHE E 1 178 ? 161.943 192.806 149.199 1.00 39.11 ? 178 PHE E CZ  1 
ATOM 5133 N N   . VAL E 1 179 ? 163.197 186.081 150.383 1.00 37.15 ? 179 VAL E N   1 
ATOM 5134 C CA  . VAL E 1 179 ? 163.999 184.899 150.677 1.00 30.20 ? 179 VAL E CA  1 
ATOM 5135 C C   . VAL E 1 179 ? 165.408 185.155 150.169 1.00 26.14 ? 179 VAL E C   1 
ATOM 5136 O O   . VAL E 1 179 ? 165.618 185.304 148.959 1.00 34.27 ? 179 VAL E O   1 
ATOM 5137 C CB  . VAL E 1 179 ? 163.414 183.627 150.041 1.00 29.16 ? 179 VAL E CB  1 
ATOM 5138 C CG1 . VAL E 1 179 ? 164.411 182.483 150.132 1.00 29.18 ? 179 VAL E CG1 1 
ATOM 5139 C CG2 . VAL E 1 179 ? 162.110 183.252 150.720 1.00 28.26 ? 179 VAL E CG2 1 
ATOM 5140 N N   . HIS E 1 180 ? 166.369 185.209 151.087 1.00 30.99 ? 180 HIS E N   1 
ATOM 5141 C CA  . HIS E 1 180 ? 167.775 185.409 150.754 1.00 35.83 ? 180 HIS E CA  1 
ATOM 5142 C C   . HIS E 1 180 ? 168.549 184.191 151.237 1.00 34.92 ? 180 HIS E C   1 
ATOM 5143 O O   . HIS E 1 180 ? 168.763 184.023 152.442 1.00 41.11 ? 180 HIS E O   1 
ATOM 5144 C CB  . HIS E 1 180 ? 168.314 186.692 151.385 1.00 37.66 ? 180 HIS E CB  1 
ATOM 5145 C CG  . HIS E 1 180 ? 168.029 187.923 150.583 1.00 37.42 ? 180 HIS E CG  1 
ATOM 5146 N ND1 . HIS E 1 180 ? 168.904 188.986 150.516 1.00 35.05 ? 180 HIS E ND1 1 
ATOM 5147 C CD2 . HIS E 1 180 ? 166.968 188.261 149.814 1.00 38.81 ? 180 HIS E CD2 1 
ATOM 5148 C CE1 . HIS E 1 180 ? 168.394 189.926 149.740 1.00 41.71 ? 180 HIS E CE1 1 
ATOM 5149 N NE2 . HIS E 1 180 ? 167.220 189.510 149.300 1.00 38.77 ? 180 HIS E NE2 1 
ATOM 5150 N N   . ASP E 1 181 ? 168.963 183.343 150.299 1.00 45.73 ? 181 ASP E N   1 
ATOM 5151 C CA  . ASP E 1 181 ? 169.690 182.119 150.606 1.00 45.25 ? 181 ASP E CA  1 
ATOM 5152 C C   . ASP E 1 181 ? 171.057 182.180 149.943 1.00 44.49 ? 181 ASP E C   1 
ATOM 5153 O O   . ASP E 1 181 ? 171.147 182.305 148.716 1.00 43.21 ? 181 ASP E O   1 
ATOM 5154 C CB  . ASP E 1 181 ? 168.915 180.887 150.135 1.00 41.27 ? 181 ASP E CB  1 
ATOM 5155 C CG  . ASP E 1 181 ? 169.480 179.596 150.690 1.00 47.44 ? 181 ASP E CG  1 
ATOM 5156 O OD1 . ASP E 1 181 ? 169.348 179.365 151.910 1.00 50.55 ? 181 ASP E OD1 1 
ATOM 5157 O OD2 . ASP E 1 181 ? 170.058 178.814 149.907 1.00 46.95 ? 181 ASP E OD2 1 
ATOM 5158 N N   . CYS E 1 182 ? 172.110 182.085 150.754 1.00 41.99 ? 182 CYS E N   1 
ATOM 5159 C CA  . CYS E 1 182 ? 173.490 182.061 150.267 1.00 37.09 ? 182 CYS E CA  1 
ATOM 5160 C C   . CYS E 1 182 ? 173.808 183.290 149.419 1.00 39.66 ? 182 CYS E C   1 
ATOM 5161 O O   . CYS E 1 182 ? 174.434 183.195 148.362 1.00 43.22 ? 182 CYS E O   1 
ATOM 5162 C CB  . CYS E 1 182 ? 173.771 180.776 149.489 1.00 40.47 ? 182 CYS E CB  1 
ATOM 5163 S SG  . CYS E 1 182 ? 173.804 179.298 150.518 1.00 63.20 ? 182 CYS E SG  1 
ATOM 5164 N N   . VAL E 1 183 ? 173.375 184.455 149.887 1.00 36.16 ? 183 VAL E N   1 
ATOM 5165 C CA  . VAL E 1 183 ? 173.601 185.714 149.191 1.00 33.28 ? 183 VAL E CA  1 
ATOM 5166 C C   . VAL E 1 183 ? 174.784 186.423 149.832 1.00 24.08 ? 183 VAL E C   1 
ATOM 5167 O O   . VAL E 1 183 ? 175.053 186.272 151.029 1.00 36.03 ? 183 VAL E O   1 
ATOM 5168 C CB  . VAL E 1 183 ? 172.338 186.601 149.212 1.00 33.36 ? 183 VAL E CB  1 
ATOM 5169 C CG1 . VAL E 1 183 ? 172.626 187.960 148.590 1.00 35.78 ? 183 VAL E CG1 1 
ATOM 5170 C CG2 . VAL E 1 183 ? 171.197 185.911 148.486 1.00 30.11 ? 183 VAL E CG2 1 
ATOM 5171 N N   . ASN E 1 184 ? 175.497 187.208 149.021 1.00 27.82 ? 184 ASN E N   1 
ATOM 5172 C CA  . ASN E 1 184 ? 176.651 187.986 149.474 1.00 35.27 ? 184 ASN E CA  1 
ATOM 5173 C C   . ASN E 1 184 ? 177.716 187.094 150.108 1.00 32.20 ? 184 ASN E C   1 
ATOM 5174 O O   . ASN E 1 184 ? 178.304 187.433 151.137 1.00 29.28 ? 184 ASN E O   1 
ATOM 5175 C CB  . ASN E 1 184 ? 176.225 189.097 150.438 1.00 33.08 ? 184 ASN E CB  1 
ATOM 5176 C CG  . ASN E 1 184 ? 175.391 190.168 149.762 1.00 32.32 ? 184 ASN E CG  1 
ATOM 5177 O OD1 . ASN E 1 184 ? 174.846 189.954 148.680 1.00 34.08 ? 184 ASN E OD1 1 
ATOM 5178 N ND2 . ASN E 1 184 ? 175.288 191.328 150.400 1.00 34.73 ? 184 ASN E ND2 1 
ATOM 5179 N N   . ILE E 1 185 ? 177.966 185.945 149.491 1.00 30.52 ? 185 ILE E N   1 
ATOM 5180 C CA  . ILE E 1 185 ? 179.015 185.035 149.935 1.00 30.93 ? 185 ILE E CA  1 
ATOM 5181 C C   . ILE E 1 185 ? 180.310 185.425 149.235 1.00 27.44 ? 185 ILE E C   1 
ATOM 5182 O O   . ILE E 1 185 ? 180.373 185.453 148.001 1.00 31.09 ? 185 ILE E O   1 
ATOM 5183 C CB  . ILE E 1 185 ? 178.647 183.573 149.643 1.00 30.18 ? 185 ILE E CB  1 
ATOM 5184 C CG1 . ILE E 1 185 ? 177.438 183.151 150.479 1.00 30.01 ? 185 ILE E CG1 1 
ATOM 5185 C CG2 . ILE E 1 185 ? 179.837 182.664 149.912 1.00 27.74 ? 185 ILE E CG2 1 
ATOM 5186 C CD1 . ILE E 1 185 ? 177.178 181.661 150.467 1.00 30.44 ? 185 ILE E CD1 1 
ATOM 5187 N N   . THR E 1 186 ? 181.341 185.725 150.018 1.00 27.62 ? 186 THR E N   1 
ATOM 5188 C CA  . THR E 1 186 ? 182.605 186.212 149.483 1.00 33.30 ? 186 THR E CA  1 
ATOM 5189 C C   . THR E 1 186 ? 183.757 185.393 150.045 1.00 30.62 ? 186 THR E C   1 
ATOM 5190 O O   . THR E 1 186 ? 183.876 185.234 151.264 1.00 24.31 ? 186 THR E O   1 
ATOM 5191 C CB  . THR E 1 186 ? 182.810 187.696 149.810 1.00 34.76 ? 186 THR E CB  1 
ATOM 5192 O OG1 . THR E 1 186 ? 181.703 188.454 149.306 1.00 42.10 ? 186 THR E OG1 1 
ATOM 5193 C CG2 . THR E 1 186 ? 184.097 188.209 149.181 1.00 33.05 ? 186 THR E CG2 1 
ATOM 5194 N N   . VAL E 1 187 ? 184.599 184.879 149.153 1.00 28.27 ? 187 VAL E N   1 
ATOM 5195 C CA  . VAL E 1 187 ? 185.858 184.236 149.513 1.00 27.56 ? 187 VAL E CA  1 
ATOM 5196 C C   . VAL E 1 187 ? 186.940 185.002 148.766 1.00 26.51 ? 187 VAL E C   1 
ATOM 5197 O O   . VAL E 1 187 ? 187.171 184.767 147.574 1.00 36.66 ? 187 VAL E O   1 
ATOM 5198 C CB  . VAL E 1 187 ? 185.878 182.745 149.161 1.00 28.93 ? 187 VAL E CB  1 
ATOM 5199 C CG1 . VAL E 1 187 ? 187.115 182.083 149.740 1.00 29.77 ? 187 VAL E CG1 1 
ATOM 5200 C CG2 . VAL E 1 187 ? 184.616 182.060 149.667 1.00 30.31 ? 187 VAL E CG2 1 
ATOM 5201 N N   . LYS E 1 188 ? 187.611 185.920 149.458 1.00 23.75 ? 188 LYS E N   1 
ATOM 5202 C CA  . LYS E 1 188 ? 188.485 186.884 148.807 1.00 29.88 ? 188 LYS E CA  1 
ATOM 5203 C C   . LYS E 1 188 ? 189.797 187.000 149.568 1.00 28.73 ? 188 LYS E C   1 
ATOM 5204 O O   . LYS E 1 188 ? 189.856 186.767 150.777 1.00 41.12 ? 188 LYS E O   1 
ATOM 5205 C CB  . LYS E 1 188 ? 187.807 188.260 148.708 1.00 29.75 ? 188 LYS E CB  1 
ATOM 5206 C CG  . LYS E 1 188 ? 188.509 189.260 147.802 1.00 28.86 ? 188 LYS E CG  1 
ATOM 5207 C CD  . LYS E 1 188 ? 187.869 190.635 147.900 1.00 27.86 ? 188 LYS E CD  1 
ATOM 5208 C CE  . LYS E 1 188 ? 188.592 191.645 147.024 1.00 38.02 ? 188 LYS E CE  1 
ATOM 5209 N NZ  . LYS E 1 188 ? 188.114 193.035 147.264 1.00 31.08 ? 188 LYS E NZ  1 
ATOM 5210 N N   . GLN E 1 189 ? 190.854 187.353 148.840 1.00 38.59 ? 189 GLN E N   1 
ATOM 5211 C CA  . GLN E 1 189 ? 192.138 187.726 149.427 1.00 40.40 ? 189 GLN E CA  1 
ATOM 5212 C C   . GLN E 1 189 ? 192.539 189.069 148.836 1.00 42.87 ? 189 GLN E C   1 
ATOM 5213 O O   . GLN E 1 189 ? 192.859 189.157 147.645 1.00 47.50 ? 189 GLN E O   1 
ATOM 5214 C CB  . GLN E 1 189 ? 193.206 186.663 149.166 1.00 40.37 ? 189 GLN E CB  1 
ATOM 5215 C CG  . GLN E 1 189 ? 193.077 185.950 147.832 1.00 44.91 ? 189 GLN E CG  1 
ATOM 5216 C CD  . GLN E 1 189 ? 194.078 184.823 147.679 1.00 46.36 ? 189 GLN E CD  1 
ATOM 5217 O OE1 . GLN E 1 189 ? 194.909 184.591 148.558 1.00 46.81 ? 189 GLN E OE1 1 
ATOM 5218 N NE2 . GLN E 1 189 ? 194.008 184.114 146.557 1.00 41.98 ? 189 GLN E NE2 1 
ATOM 5219 N N   . HIS E 1 190 ? 192.520 190.113 149.660 1.00 35.85 ? 190 HIS E N   1 
ATOM 5220 C CA  . HIS E 1 190 ? 192.758 191.476 149.210 1.00 37.93 ? 190 HIS E CA  1 
ATOM 5221 C C   . HIS E 1 190 ? 193.990 192.048 149.895 1.00 33.62 ? 190 HIS E C   1 
ATOM 5222 O O   . HIS E 1 190 ? 194.185 191.865 151.101 1.00 42.85 ? 190 HIS E O   1 
ATOM 5223 C CB  . HIS E 1 190 ? 191.542 192.366 149.488 1.00 42.39 ? 190 HIS E CB  1 
ATOM 5224 C CG  . HIS E 1 190 ? 191.700 193.773 149.006 1.00 40.73 ? 190 HIS E CG  1 
ATOM 5225 N ND1 . HIS E 1 190 ? 192.405 194.094 147.866 1.00 44.85 ? 190 HIS E ND1 1 
ATOM 5226 C CD2 . HIS E 1 190 ? 191.239 194.944 149.505 1.00 41.50 ? 190 HIS E CD2 1 
ATOM 5227 C CE1 . HIS E 1 190 ? 192.376 195.403 147.687 1.00 44.48 ? 190 HIS E CE1 1 
ATOM 5228 N NE2 . HIS E 1 190 ? 191.674 195.942 148.667 1.00 42.65 ? 190 HIS E NE2 1 
ATOM 5229 N N   . THR E 1 191 ? 194.820 192.740 149.118 1.00 34.10 ? 191 THR E N   1 
ATOM 5230 C CA  . THR E 1 191 ? 196.037 193.361 149.622 1.00 41.72 ? 191 THR E CA  1 
ATOM 5231 C C   . THR E 1 191 ? 196.102 194.800 149.135 1.00 42.88 ? 191 THR E C   1 
ATOM 5232 O O   . THR E 1 191 ? 195.897 195.065 147.946 1.00 44.24 ? 191 THR E O   1 
ATOM 5233 C CB  . THR E 1 191 ? 197.285 192.597 149.164 1.00 41.33 ? 191 THR E CB  1 
ATOM 5234 O OG1 . THR E 1 191 ? 197.238 191.257 149.666 1.00 42.79 ? 191 THR E OG1 1 
ATOM 5235 C CG2 . THR E 1 191 ? 198.545 193.276 149.678 1.00 39.36 ? 191 THR E CG2 1 
ATOM 5236 N N   . VAL E 1 192 ? 196.386 195.722 150.050 1.00 40.34 ? 192 VAL E N   1 
ATOM 5237 C CA  . VAL E 1 192 ? 196.559 197.133 149.728 1.00 37.48 ? 192 VAL E CA  1 
ATOM 5238 C C   . VAL E 1 192 ? 197.985 197.519 150.088 1.00 39.45 ? 192 VAL E C   1 
ATOM 5239 O O   . VAL E 1 192 ? 198.413 197.335 151.235 1.00 46.10 ? 192 VAL E O   1 
ATOM 5240 C CB  . VAL E 1 192 ? 195.547 198.019 150.471 1.00 41.29 ? 192 VAL E CB  1 
ATOM 5241 C CG1 . VAL E 1 192 ? 195.702 199.470 150.043 1.00 45.82 ? 192 VAL E CG1 1 
ATOM 5242 C CG2 . VAL E 1 192 ? 194.131 197.531 150.221 1.00 39.03 ? 192 VAL E CG2 1 
ATOM 5243 N N   . THR E 1 193 ? 198.719 198.049 149.113 1.00 48.16 ? 193 THR E N   1 
ATOM 5244 C CA  . THR E 1 193 ? 200.100 198.470 149.304 1.00 50.71 ? 193 THR E CA  1 
ATOM 5245 C C   . THR E 1 193 ? 200.212 199.962 149.033 1.00 49.11 ? 193 THR E C   1 
ATOM 5246 O O   . THR E 1 193 ? 199.825 200.433 147.958 1.00 49.10 ? 193 THR E O   1 
ATOM 5247 C CB  . THR E 1 193 ? 201.050 197.694 148.387 1.00 52.40 ? 193 THR E CB  1 
ATOM 5248 O OG1 . THR E 1 193 ? 200.898 196.288 148.615 1.00 48.44 ? 193 THR E OG1 1 
ATOM 5249 C CG2 . THR E 1 193 ? 202.493 198.095 148.656 1.00 51.56 ? 193 THR E CG2 1 
ATOM 5250 N N   . THR E 1 194 ? 200.742 200.701 150.008 1.00 46.47 ? 194 THR E N   1 
ATOM 5251 C CA  . THR E 1 194 ? 200.960 202.145 149.882 1.00 49.09 ? 194 THR E CA  1 
ATOM 5252 C C   . THR E 1 194 ? 202.319 202.452 150.510 1.00 50.70 ? 194 THR E C   1 
ATOM 5253 O O   . THR E 1 194 ? 202.416 202.700 151.715 1.00 52.14 ? 194 THR E O   1 
ATOM 5254 C CB  . THR E 1 194 ? 199.840 202.941 150.540 1.00 49.30 ? 194 THR E CB  1 
ATOM 5255 O OG1 . THR E 1 194 ? 198.573 202.469 150.065 1.00 46.94 ? 194 THR E OG1 1 
ATOM 5256 C CG2 . THR E 1 194 ? 199.977 204.420 150.209 1.00 47.45 ? 194 THR E CG2 1 
ATOM 5257 N N   . THR E 1 195 ? 203.361 202.433 149.686 1.00 49.04 ? 195 THR E N   1 
ATOM 5258 C CA  . THR E 1 195 ? 204.725 202.678 150.133 1.00 53.61 ? 195 THR E CA  1 
ATOM 5259 C C   . THR E 1 195 ? 205.229 203.983 149.533 1.00 52.35 ? 195 THR E C   1 
ATOM 5260 O O   . THR E 1 195 ? 205.135 204.191 148.319 1.00 49.17 ? 195 THR E O   1 
ATOM 5261 C CB  . THR E 1 195 ? 205.650 201.525 149.737 1.00 50.40 ? 195 THR E CB  1 
ATOM 5262 O OG1 . THR E 1 195 ? 205.140 200.296 150.269 1.00 52.03 ? 195 THR E OG1 1 
ATOM 5263 C CG2 . THR E 1 195 ? 207.052 201.761 150.277 1.00 51.02 ? 195 THR E CG2 1 
ATOM 5264 N N   . THR E 1 196 ? 205.760 204.854 150.385 1.00 53.59 ? 196 THR E N   1 
ATOM 5265 C CA  . THR E 1 196 ? 206.303 206.139 149.969 1.00 52.66 ? 196 THR E CA  1 
ATOM 5266 C C   . THR E 1 196 ? 207.802 206.190 150.227 1.00 54.50 ? 196 THR E C   1 
ATOM 5267 O O   . THR E 1 196 ? 208.244 205.984 151.362 1.00 53.08 ? 196 THR E O   1 
ATOM 5268 C CB  . THR E 1 196 ? 205.631 207.291 150.720 1.00 55.14 ? 196 THR E CB  1 
ATOM 5269 O OG1 . THR E 1 196 ? 204.206 207.149 150.638 1.00 54.11 ? 196 THR E OG1 1 
ATOM 5270 C CG2 . THR E 1 196 ? 206.036 208.628 150.117 1.00 55.02 ? 196 THR E CG2 1 
ATOM 5271 N N   . LYS E 1 197 ? 208.566 206.473 149.170 1.00 65.56 ? 197 LYS E N   1 
ATOM 5272 C CA  . LYS E 1 197 ? 210.031 206.569 149.193 1.00 65.81 ? 197 LYS E CA  1 
ATOM 5273 C C   . LYS E 1 197 ? 210.655 205.441 150.016 1.00 65.64 ? 197 LYS E C   1 
ATOM 5274 O O   . LYS E 1 197 ? 211.514 205.655 150.874 1.00 64.86 ? 197 LYS E O   1 
ATOM 5275 C CB  . LYS E 1 197 ? 210.515 207.945 149.672 1.00 64.87 ? 197 LYS E CB  1 
ATOM 5276 C CG  . LYS E 1 197 ? 210.006 208.413 151.029 1.00 62.96 ? 197 LYS E CG  1 
ATOM 5277 C CD  . LYS E 1 197 ? 210.603 209.759 151.406 1.00 64.76 ? 197 LYS E CD  1 
ATOM 5278 C CE  . LYS E 1 197 ? 210.015 210.880 150.561 1.00 65.57 ? 197 LYS E CE  1 
ATOM 5279 N NZ  . LYS E 1 197 ? 208.542 210.999 150.740 1.00 63.84 ? 197 LYS E NZ  1 
ATOM 5280 N N   . GLY E 1 198 ? 210.213 204.218 149.736 1.00 60.50 ? 198 GLY E N   1 
ATOM 5281 C CA  . GLY E 1 198 ? 210.792 203.046 150.364 1.00 59.33 ? 198 GLY E CA  1 
ATOM 5282 C C   . GLY E 1 198 ? 212.100 202.649 149.715 1.00 59.91 ? 198 GLY E C   1 
ATOM 5283 O O   . GLY E 1 198 ? 212.125 202.268 148.540 1.00 61.04 ? 198 GLY E O   1 
ATOM 5284 N N   . GLU E 1 199 ? 213.195 202.731 150.465 1.00 58.39 ? 199 GLU E N   1 
ATOM 5285 C CA  . GLU E 1 199 ? 214.532 202.509 149.933 1.00 60.87 ? 199 GLU E CA  1 
ATOM 5286 C C   . GLU E 1 199 ? 215.135 201.247 150.534 1.00 60.52 ? 199 GLU E C   1 
ATOM 5287 O O   . GLU E 1 199 ? 215.159 201.088 151.759 1.00 59.17 ? 199 GLU E O   1 
ATOM 5288 C CB  . GLU E 1 199 ? 215.437 203.710 150.217 1.00 62.13 ? 199 GLU E CB  1 
ATOM 5289 C CG  . GLU E 1 199 ? 215.008 204.988 149.515 1.00 63.39 ? 199 GLU E CG  1 
ATOM 5290 C CD  . GLU E 1 199 ? 215.800 206.198 149.973 1.00 64.46 ? 199 GLU E CD  1 
ATOM 5291 O OE1 . GLU E 1 199 ? 216.316 206.177 151.109 1.00 61.74 ? 199 GLU E OE1 1 
ATOM 5292 O OE2 . GLU E 1 199 ? 215.906 207.169 149.194 1.00 64.33 ? 199 GLU E OE2 1 
ATOM 5293 N N   . ASN E 1 200 ? 215.623 200.358 149.664 1.00 68.57 ? 200 ASN E N   1 
ATOM 5294 C CA  . ASN E 1 200 ? 216.361 199.160 150.069 1.00 68.12 ? 200 ASN E CA  1 
ATOM 5295 C C   . ASN E 1 200 ? 215.556 198.290 151.031 1.00 63.31 ? 200 ASN E C   1 
ATOM 5296 O O   . ASN E 1 200 ? 216.093 197.740 151.994 1.00 63.03 ? 200 ASN E O   1 
ATOM 5297 C CB  . ASN E 1 200 ? 217.714 199.530 150.680 1.00 65.91 ? 200 ASN E CB  1 
ATOM 5298 C CG  . ASN E 1 200 ? 218.547 200.406 149.765 1.00 68.81 ? 200 ASN E CG  1 
ATOM 5299 O OD1 . ASN E 1 200 ? 218.510 201.633 149.857 1.00 69.14 ? 200 ASN E OD1 1 
ATOM 5300 N ND2 . ASN E 1 200 ? 219.305 199.777 148.873 1.00 67.93 ? 200 ASN E ND2 1 
ATOM 5301 N N   . PHE E 1 201 ? 214.260 198.149 150.765 1.00 51.68 ? 201 PHE E N   1 
ATOM 5302 C CA  . PHE E 1 201 ? 213.383 197.363 151.618 1.00 54.38 ? 201 PHE E CA  1 
ATOM 5303 C C   . PHE E 1 201 ? 212.771 196.212 150.830 1.00 52.48 ? 201 PHE E C   1 
ATOM 5304 O O   . PHE E 1 201 ? 212.538 196.316 149.622 1.00 53.11 ? 201 PHE E O   1 
ATOM 5305 C CB  . PHE E 1 201 ? 212.284 198.239 152.245 1.00 55.05 ? 201 PHE E CB  1 
ATOM 5306 C CG  . PHE E 1 201 ? 211.031 198.353 151.419 1.00 56.16 ? 201 PHE E CG  1 
ATOM 5307 C CD1 . PHE E 1 201 ? 210.894 199.363 150.483 1.00 52.21 ? 201 PHE E CD1 1 
ATOM 5308 C CD2 . PHE E 1 201 ? 209.974 197.471 151.603 1.00 54.54 ? 201 PHE E CD2 1 
ATOM 5309 C CE1 . PHE E 1 201 ? 209.741 199.479 149.731 1.00 50.84 ? 201 PHE E CE1 1 
ATOM 5310 C CE2 . PHE E 1 201 ? 208.821 197.582 150.850 1.00 51.94 ? 201 PHE E CE2 1 
ATOM 5311 C CZ  . PHE E 1 201 ? 208.705 198.588 149.914 1.00 52.23 ? 201 PHE E CZ  1 
ATOM 5312 N N   . THR E 1 202 ? 212.514 195.113 151.530 1.00 52.32 ? 202 THR E N   1 
ATOM 5313 C CA  . THR E 1 202 ? 211.936 193.912 150.943 1.00 53.03 ? 202 THR E CA  1 
ATOM 5314 C C   . THR E 1 202 ? 210.506 193.745 151.435 1.00 50.78 ? 202 THR E C   1 
ATOM 5315 O O   . THR E 1 202 ? 210.250 193.794 152.642 1.00 53.86 ? 202 THR E O   1 
ATOM 5316 C CB  . THR E 1 202 ? 212.763 192.674 151.297 1.00 50.28 ? 202 THR E CB  1 
ATOM 5317 O OG1 . THR E 1 202 ? 214.101 192.834 150.807 1.00 53.98 ? 202 THR E OG1 1 
ATOM 5318 C CG2 . THR E 1 202 ? 212.149 191.426 150.679 1.00 50.97 ? 202 THR E CG2 1 
ATOM 5319 N N   . GLU E 1 203 ? 209.581 193.552 150.500 1.00 51.17 ? 203 GLU E N   1 
ATOM 5320 C CA  . GLU E 1 203 ? 208.170 193.360 150.808 1.00 48.56 ? 203 GLU E CA  1 
ATOM 5321 C C   . GLU E 1 203 ? 207.759 191.944 150.433 1.00 50.88 ? 203 GLU E C   1 
ATOM 5322 O O   . GLU E 1 203 ? 207.962 191.516 149.292 1.00 53.33 ? 203 GLU E O   1 
ATOM 5323 C CB  . GLU E 1 203 ? 207.305 194.377 150.061 1.00 52.89 ? 203 GLU E CB  1 
ATOM 5324 C CG  . GLU E 1 203 ? 205.825 194.286 150.388 1.00 56.11 ? 203 GLU E CG  1 
ATOM 5325 C CD  . GLU E 1 203 ? 205.004 195.336 149.668 1.00 55.62 ? 203 GLU E CD  1 
ATOM 5326 O OE1 . GLU E 1 203 ? 205.586 196.114 148.884 1.00 53.41 ? 203 GLU E OE1 1 
ATOM 5327 O OE2 . GLU E 1 203 ? 203.776 195.382 149.887 1.00 55.09 ? 203 GLU E OE2 1 
ATOM 5328 N N   . THR E 1 204 ? 207.187 191.222 151.393 1.00 52.68 ? 204 THR E N   1 
ATOM 5329 C CA  . THR E 1 204 ? 206.721 189.858 151.175 1.00 54.63 ? 204 THR E CA  1 
ATOM 5330 C C   . THR E 1 204 ? 205.259 189.761 151.584 1.00 51.93 ? 204 THR E C   1 
ATOM 5331 O O   . THR E 1 204 ? 204.912 190.052 152.733 1.00 57.57 ? 204 THR E O   1 
ATOM 5332 C CB  . THR E 1 204 ? 207.559 188.849 151.968 1.00 53.25 ? 204 THR E CB  1 
ATOM 5333 O OG1 . THR E 1 204 ? 208.935 188.960 151.582 1.00 55.87 ? 204 THR E OG1 1 
ATOM 5334 C CG2 . THR E 1 204 ? 207.076 187.433 151.703 1.00 52.63 ? 204 THR E CG2 1 
ATOM 5335 N N   . ASP E 1 205 ? 204.413 189.335 150.648 1.00 44.95 ? 205 ASP E N   1 
ATOM 5336 C CA  . ASP E 1 205 ? 202.974 189.198 150.871 1.00 45.63 ? 205 ASP E CA  1 
ATOM 5337 C C   . ASP E 1 205 ? 202.548 187.825 150.362 1.00 48.71 ? 205 ASP E C   1 
ATOM 5338 O O   . ASP E 1 205 ? 202.322 187.641 149.163 1.00 55.01 ? 205 ASP E O   1 
ATOM 5339 C CB  . ASP E 1 205 ? 202.196 190.309 150.169 1.00 51.54 ? 205 ASP E CB  1 
ATOM 5340 C CG  . ASP E 1 205 ? 202.380 191.663 150.829 1.00 56.86 ? 205 ASP E CG  1 
ATOM 5341 O OD1 . ASP E 1 205 ? 202.868 191.710 151.977 1.00 54.93 ? 205 ASP E OD1 1 
ATOM 5342 O OD2 . ASP E 1 205 ? 202.037 192.683 150.197 1.00 56.78 ? 205 ASP E OD2 1 
ATOM 5343 N N   . ILE E 1 206 ? 202.441 186.861 151.273 1.00 41.34 ? 206 ILE E N   1 
ATOM 5344 C CA  . ILE E 1 206 ? 202.029 185.501 150.947 1.00 44.19 ? 206 ILE E CA  1 
ATOM 5345 C C   . ILE E 1 206 ? 200.688 185.235 151.615 1.00 39.49 ? 206 ILE E C   1 
ATOM 5346 O O   . ILE E 1 206 ? 200.547 185.406 152.832 1.00 43.70 ? 206 ILE E O   1 
ATOM 5347 C CB  . ILE E 1 206 ? 203.078 184.469 151.393 1.00 37.28 ? 206 ILE E CB  1 
ATOM 5348 C CG1 . ILE E 1 206 ? 204.444 184.801 150.790 1.00 41.77 ? 206 ILE E CG1 1 
ATOM 5349 C CG2 . ILE E 1 206 ? 202.646 183.066 150.993 1.00 33.21 ? 206 ILE E CG2 1 
ATOM 5350 C CD1 . ILE E 1 206 ? 205.536 183.836 151.192 1.00 42.50 ? 206 ILE E CD1 1 
ATOM 5351 N N   . LYS E 1 207 ? 199.703 184.821 150.818 1.00 36.66 ? 207 LYS E N   1 
ATOM 5352 C CA  . LYS E 1 207 ? 198.366 184.487 151.309 1.00 35.07 ? 207 LYS E CA  1 
ATOM 5353 C C   . LYS E 1 207 ? 198.009 183.116 150.746 1.00 37.98 ? 207 LYS E C   1 
ATOM 5354 O O   . LYS E 1 207 ? 197.419 183.010 149.667 1.00 43.11 ? 207 LYS E O   1 
ATOM 5355 C CB  . LYS E 1 207 ? 197.351 185.554 150.914 1.00 40.96 ? 207 LYS E CB  1 
ATOM 5356 C CG  . LYS E 1 207 ? 197.573 186.894 151.591 1.00 41.93 ? 207 LYS E CG  1 
ATOM 5357 C CD  . LYS E 1 207 ? 196.480 187.883 151.236 1.00 39.80 ? 207 LYS E CD  1 
ATOM 5358 C CE  . LYS E 1 207 ? 196.646 189.175 152.014 1.00 40.21 ? 207 LYS E CE  1 
ATOM 5359 N NZ  . LYS E 1 207 ? 197.820 189.957 151.540 1.00 41.69 ? 207 LYS E NZ  1 
ATOM 5360 N N   . MET E 1 208 ? 198.372 182.067 151.479 1.00 49.38 ? 208 MET E N   1 
ATOM 5361 C CA  . MET E 1 208 ? 198.002 180.717 151.082 1.00 46.82 ? 208 MET E CA  1 
ATOM 5362 C C   . MET E 1 208 ? 196.510 180.502 151.293 1.00 42.45 ? 208 MET E C   1 
ATOM 5363 O O   . MET E 1 208 ? 195.945 180.911 152.310 1.00 51.23 ? 208 MET E O   1 
ATOM 5364 C CB  . MET E 1 208 ? 198.789 179.689 151.896 1.00 47.70 ? 208 MET E CB  1 
ATOM 5365 C CG  . MET E 1 208 ? 200.281 179.677 151.612 1.00 51.54 ? 208 MET E CG  1 
ATOM 5366 S SD  . MET E 1 208 ? 201.167 178.508 152.661 1.00 68.67 ? 208 MET E SD  1 
ATOM 5367 C CE  . MET E 1 208 ? 202.855 178.784 152.125 1.00 54.38 ? 208 MET E CE  1 
ATOM 5368 N N   . MET E 1 209 ? 195.866 179.862 150.317 1.00 44.54 ? 209 MET E N   1 
ATOM 5369 C CA  . MET E 1 209 ? 194.424 179.605 150.353 1.00 45.03 ? 209 MET E CA  1 
ATOM 5370 C C   . MET E 1 209 ? 194.202 178.208 149.774 1.00 51.23 ? 209 MET E C   1 
ATOM 5371 O O   . MET E 1 209 ? 194.065 178.045 148.560 1.00 56.05 ? 209 MET E O   1 
ATOM 5372 C CB  . MET E 1 209 ? 193.674 180.678 149.570 1.00 52.34 ? 209 MET E CB  1 
ATOM 5373 C CG  . MET E 1 209 ? 192.246 180.925 150.014 1.00 52.52 ? 209 MET E CG  1 
ATOM 5374 S SD  . MET E 1 209 ? 192.139 182.031 151.433 1.00 58.69 ? 209 MET E SD  1 
ATOM 5375 C CE  . MET E 1 209 ? 190.379 182.357 151.481 1.00 43.13 ? 209 MET E CE  1 
ATOM 5376 N N   . GLU E 1 210 ? 194.170 177.205 150.650 1.00 47.20 ? 210 GLU E N   1 
ATOM 5377 C CA  . GLU E 1 210 ? 194.058 175.813 150.233 1.00 50.27 ? 210 GLU E CA  1 
ATOM 5378 C C   . GLU E 1 210 ? 192.950 175.125 151.014 1.00 43.23 ? 210 GLU E C   1 
ATOM 5379 O O   . GLU E 1 210 ? 192.908 175.215 152.244 1.00 42.12 ? 210 GLU E O   1 
ATOM 5380 C CB  . GLU E 1 210 ? 195.382 175.067 150.431 1.00 48.50 ? 210 GLU E CB  1 
ATOM 5381 C CG  . GLU E 1 210 ? 196.407 175.329 149.344 1.00 51.76 ? 210 GLU E CG  1 
ATOM 5382 C CD  . GLU E 1 210 ? 197.298 174.131 149.090 1.00 53.42 ? 210 GLU E CD  1 
ATOM 5383 O OE1 . GLU E 1 210 ? 197.416 173.275 149.992 1.00 55.46 ? 210 GLU E OE1 1 
ATOM 5384 O OE2 . GLU E 1 210 ? 197.876 174.042 147.987 1.00 50.29 ? 210 GLU E OE2 1 
ATOM 5385 N N   . ARG E 1 211 ? 192.060 174.439 150.293 1.00 45.35 ? 211 ARG E N   1 
ATOM 5386 C CA  . ARG E 1 211 ? 190.981 173.654 150.898 1.00 46.47 ? 211 ARG E CA  1 
ATOM 5387 C C   . ARG E 1 211 ? 190.159 174.505 151.864 1.00 46.82 ? 211 ARG E C   1 
ATOM 5388 O O   . ARG E 1 211 ? 189.712 174.041 152.914 1.00 46.12 ? 211 ARG E O   1 
ATOM 5389 C CB  . ARG E 1 211 ? 191.542 172.413 151.595 1.00 47.45 ? 211 ARG E CB  1 
ATOM 5390 C CG  . ARG E 1 211 ? 190.668 171.170 151.499 1.00 45.59 ? 211 ARG E CG  1 
ATOM 5391 C CD  . ARG E 1 211 ? 191.399 169.959 152.064 1.00 45.05 ? 211 ARG E CD  1 
ATOM 5392 N NE  . ARG E 1 211 ? 190.507 169.060 152.784 1.00 48.98 ? 211 ARG E NE  1 
ATOM 5393 C CZ  . ARG E 1 211 ? 190.913 168.040 153.526 1.00 50.76 ? 211 ARG E CZ  1 
ATOM 5394 N NH1 . ARG E 1 211 ? 192.197 167.759 153.672 1.00 49.50 ? 211 ARG E NH1 1 
ATOM 5395 N NH2 . ARG E 1 211 ? 190.007 167.286 154.144 1.00 47.89 ? 211 ARG E NH2 1 
ATOM 5396 N N   . VAL E 1 212 ? 189.947 175.768 151.490 1.00 48.66 ? 212 VAL E N   1 
ATOM 5397 C CA  . VAL E 1 212 ? 189.364 176.746 152.405 1.00 45.24 ? 212 VAL E CA  1 
ATOM 5398 C C   . VAL E 1 212 ? 187.867 176.523 152.576 1.00 46.06 ? 212 VAL E C   1 
ATOM 5399 O O   . VAL E 1 212 ? 187.347 176.594 153.694 1.00 51.41 ? 212 VAL E O   1 
ATOM 5400 C CB  . VAL E 1 212 ? 189.678 178.173 151.925 1.00 45.29 ? 212 VAL E CB  1 
ATOM 5401 C CG1 . VAL E 1 212 ? 188.844 179.187 152.688 1.00 45.67 ? 212 VAL E CG1 1 
ATOM 5402 C CG2 . VAL E 1 212 ? 191.147 178.459 152.121 1.00 47.61 ? 212 VAL E CG2 1 
ATOM 5403 N N   . VAL E 1 213 ? 187.144 176.312 151.479 1.00 40.84 ? 213 VAL E N   1 
ATOM 5404 C CA  . VAL E 1 213 ? 185.738 175.920 151.517 1.00 41.21 ? 213 VAL E CA  1 
ATOM 5405 C C   . VAL E 1 213 ? 185.599 174.686 150.638 1.00 47.58 ? 213 VAL E C   1 
ATOM 5406 O O   . VAL E 1 213 ? 185.818 174.754 149.424 1.00 48.73 ? 213 VAL E O   1 
ATOM 5407 C CB  . VAL E 1 213 ? 184.807 177.050 151.049 1.00 44.20 ? 213 VAL E CB  1 
ATOM 5408 C CG1 . VAL E 1 213 ? 183.354 176.673 151.288 1.00 41.51 ? 213 VAL E CG1 1 
ATOM 5409 C CG2 . VAL E 1 213 ? 185.142 178.354 151.761 1.00 44.98 ? 213 VAL E CG2 1 
ATOM 5410 N N   . GLU E 1 214 ? 185.190 173.567 151.231 1.00 49.20 ? 214 GLU E N   1 
ATOM 5411 C CA  . GLU E 1 214 ? 185.025 172.353 150.440 1.00 43.81 ? 214 GLU E CA  1 
ATOM 5412 C C   . GLU E 1 214 ? 183.612 172.235 149.891 1.00 42.04 ? 214 GLU E C   1 
ATOM 5413 O O   . GLU E 1 214 ? 183.435 171.859 148.730 1.00 48.73 ? 214 GLU E O   1 
ATOM 5414 C CB  . GLU E 1 214 ? 185.382 171.110 151.263 1.00 47.54 ? 214 GLU E CB  1 
ATOM 5415 C CG  . GLU E 1 214 ? 186.870 170.828 151.378 1.00 44.93 ? 214 GLU E CG  1 
ATOM 5416 C CD  . GLU E 1 214 ? 187.156 169.540 152.124 1.00 49.26 ? 214 GLU E CD  1 
ATOM 5417 O OE1 . GLU E 1 214 ? 186.312 169.130 152.950 1.00 50.88 ? 214 GLU E OE1 1 
ATOM 5418 O OE2 . GLU E 1 214 ? 188.224 168.937 151.893 1.00 51.10 ? 214 GLU E OE2 1 
ATOM 5419 N N   . GLN E 1 215 ? 182.602 172.547 150.698 1.00 37.13 ? 215 GLN E N   1 
ATOM 5420 C CA  . GLN E 1 215 ? 181.218 172.532 150.253 1.00 36.66 ? 215 GLN E CA  1 
ATOM 5421 C C   . GLN E 1 215 ? 180.480 173.720 150.850 1.00 42.88 ? 215 GLN E C   1 
ATOM 5422 O O   . GLN E 1 215 ? 180.810 174.189 151.942 1.00 43.51 ? 215 GLN E O   1 
ATOM 5423 C CB  . GLN E 1 215 ? 180.526 171.222 150.653 1.00 40.01 ? 215 GLN E CB  1 
ATOM 5424 C CG  . GLN E 1 215 ? 180.844 170.056 149.739 1.00 38.49 ? 215 GLN E CG  1 
ATOM 5425 C CD  . GLN E 1 215 ? 182.134 169.355 150.115 1.00 43.54 ? 215 GLN E CD  1 
ATOM 5426 O OE1 . GLN E 1 215 ? 182.472 169.239 151.292 1.00 44.42 ? 215 GLN E OE1 1 
ATOM 5427 N NE2 . GLN E 1 215 ? 182.871 168.903 149.111 1.00 37.51 ? 215 GLN E NE2 1 
ATOM 5428 N N   . MET E 1 216 ? 179.473 174.198 150.123 1.00 48.32 ? 216 MET E N   1 
ATOM 5429 C CA  . MET E 1 216 ? 178.662 175.316 150.584 1.00 43.39 ? 216 MET E CA  1 
ATOM 5430 C C   . MET E 1 216 ? 177.338 175.286 149.837 1.00 40.31 ? 216 MET E C   1 
ATOM 5431 O O   . MET E 1 216 ? 177.315 175.088 148.622 1.00 42.89 ? 216 MET E O   1 
ATOM 5432 C CB  . MET E 1 216 ? 179.383 176.655 150.380 1.00 41.54 ? 216 MET E CB  1 
ATOM 5433 C CG  . MET E 1 216 ? 178.748 177.820 151.121 1.00 44.60 ? 216 MET E CG  1 
ATOM 5434 S SD  . MET E 1 216 ? 179.857 179.227 151.326 1.00 53.13 ? 216 MET E SD  1 
ATOM 5435 C CE  . MET E 1 216 ? 180.878 179.084 149.862 1.00 49.74 ? 216 MET E CE  1 
ATOM 5436 N N   . CYS E 1 217 ? 176.244 175.489 150.576 1.00 43.52 ? 217 CYS E N   1 
ATOM 5437 C CA  . CYS E 1 217 ? 174.894 175.527 150.007 1.00 39.89 ? 217 CYS E CA  1 
ATOM 5438 C C   . CYS E 1 217 ? 174.573 174.264 149.213 1.00 39.07 ? 217 CYS E C   1 
ATOM 5439 O O   . CYS E 1 217 ? 173.962 174.319 148.144 1.00 39.65 ? 217 CYS E O   1 
ATOM 5440 C CB  . CYS E 1 217 ? 174.708 176.771 149.137 1.00 39.68 ? 217 CYS E CB  1 
ATOM 5441 S SG  . CYS E 1 217 ? 175.416 178.272 149.838 1.00 56.99 ? 217 CYS E SG  1 
ATOM 5442 N N   . ILE E 1 218 ? 174.979 173.113 149.744 1.00 39.60 ? 218 ILE E N   1 
ATOM 5443 C CA  . ILE E 1 218 ? 174.742 171.828 149.084 1.00 40.89 ? 218 ILE E CA  1 
ATOM 5444 C C   . ILE E 1 218 ? 173.373 171.345 149.555 1.00 37.93 ? 218 ILE E C   1 
ATOM 5445 O O   . ILE E 1 218 ? 173.234 170.715 150.603 1.00 43.77 ? 218 ILE E O   1 
ATOM 5446 C CB  . ILE E 1 218 ? 175.847 170.817 149.378 1.00 38.54 ? 218 ILE E CB  1 
ATOM 5447 C CG1 . ILE E 1 218 ? 177.222 171.434 149.116 1.00 40.26 ? 218 ILE E CG1 1 
ATOM 5448 C CG2 . ILE E 1 218 ? 175.654 169.564 148.542 1.00 33.45 ? 218 ILE E CG2 1 
ATOM 5449 C CD1 . ILE E 1 218 ? 177.380 172.032 147.745 1.00 36.50 ? 218 ILE E CD1 1 
ATOM 5450 N N   . THR E 1 219 ? 172.346 171.652 148.765 1.00 27.02 ? 219 THR E N   1 
ATOM 5451 C CA  . THR E 1 219 ? 170.987 171.185 149.037 1.00 30.50 ? 219 THR E CA  1 
ATOM 5452 C C   . THR E 1 219 ? 170.816 169.849 148.327 1.00 34.48 ? 219 THR E C   1 
ATOM 5453 O O   . THR E 1 219 ? 170.339 169.776 147.194 1.00 35.24 ? 219 THR E O   1 
ATOM 5454 C CB  . THR E 1 219 ? 169.956 172.207 148.577 1.00 33.52 ? 219 THR E CB  1 
ATOM 5455 O OG1 . THR E 1 219 ? 170.302 173.501 149.090 1.00 36.53 ? 219 THR E OG1 1 
ATOM 5456 C CG2 . THR E 1 219 ? 168.572 171.826 149.078 1.00 32.51 ? 219 THR E CG2 1 
ATOM 5457 N N   . GLN E 1 220 ? 171.214 168.777 149.005 1.00 27.57 ? 220 GLN E N   1 
ATOM 5458 C CA  . GLN E 1 220 ? 171.220 167.439 148.432 1.00 24.68 ? 220 GLN E CA  1 
ATOM 5459 C C   . GLN E 1 220 ? 170.215 166.559 149.160 1.00 19.70 ? 220 GLN E C   1 
ATOM 5460 O O   . GLN E 1 220 ? 170.260 166.444 150.389 1.00 31.43 ? 220 GLN E O   1 
ATOM 5461 C CB  . GLN E 1 220 ? 172.617 166.820 148.511 1.00 26.51 ? 220 GLN E CB  1 
ATOM 5462 C CG  . GLN E 1 220 ? 172.850 165.682 147.535 1.00 31.04 ? 220 GLN E CG  1 
ATOM 5463 C CD  . GLN E 1 220 ? 174.321 165.397 147.314 1.00 32.04 ? 220 GLN E CD  1 
ATOM 5464 O OE1 . GLN E 1 220 ? 175.030 164.992 148.234 1.00 34.98 ? 220 GLN E OE1 1 
ATOM 5465 N NE2 . GLN E 1 220 ? 174.787 165.607 146.090 1.00 27.30 ? 220 GLN E NE2 1 
ATOM 5466 N N   . TYR E 1 221 ? 169.313 165.941 148.403 1.00 18.91 ? 221 TYR E N   1 
ATOM 5467 C CA  . TYR E 1 221 ? 168.356 164.983 148.938 1.00 26.03 ? 221 TYR E CA  1 
ATOM 5468 C C   . TYR E 1 221 ? 168.799 163.590 148.516 1.00 28.67 ? 221 TYR E C   1 
ATOM 5469 O O   . TYR E 1 221 ? 168.949 163.318 147.319 1.00 27.26 ? 221 TYR E O   1 
ATOM 5470 C CB  . TYR E 1 221 ? 166.936 165.273 148.448 1.00 31.08 ? 221 TYR E CB  1 
ATOM 5471 C CG  . TYR E 1 221 ? 166.439 166.671 148.752 1.00 34.35 ? 221 TYR E CG  1 
ATOM 5472 C CD1 . TYR E 1 221 ? 167.017 167.437 149.756 1.00 32.87 ? 221 TYR E CD1 1 
ATOM 5473 C CD2 . TYR E 1 221 ? 165.385 167.221 148.036 1.00 32.90 ? 221 TYR E CD2 1 
ATOM 5474 C CE1 . TYR E 1 221 ? 166.567 168.713 150.032 1.00 32.11 ? 221 TYR E CE1 1 
ATOM 5475 C CE2 . TYR E 1 221 ? 164.924 168.495 148.307 1.00 31.97 ? 221 TYR E CE2 1 
ATOM 5476 C CZ  . TYR E 1 221 ? 165.519 169.236 149.306 1.00 34.85 ? 221 TYR E CZ  1 
ATOM 5477 O OH  . TYR E 1 221 ? 165.066 170.506 149.579 1.00 40.38 ? 221 TYR E OH  1 
ATOM 5478 N N   . GLN E 1 222 ? 169.010 162.713 149.493 1.00 28.93 ? 222 GLN E N   1 
ATOM 5479 C CA  . GLN E 1 222 ? 169.560 161.386 149.258 1.00 19.01 ? 222 GLN E CA  1 
ATOM 5480 C C   . GLN E 1 222 ? 168.563 160.328 149.705 1.00 20.66 ? 222 GLN E C   1 
ATOM 5481 O O   . GLN E 1 222 ? 167.999 160.424 150.800 1.00 30.48 ? 222 GLN E O   1 
ATOM 5482 C CB  . GLN E 1 222 ? 170.886 161.206 149.997 1.00 23.57 ? 222 GLN E CB  1 
ATOM 5483 C CG  . GLN E 1 222 ? 172.018 162.073 149.478 1.00 31.19 ? 222 GLN E CG  1 
ATOM 5484 C CD  . GLN E 1 222 ? 173.325 161.808 150.197 1.00 31.12 ? 222 GLN E CD  1 
ATOM 5485 O OE1 . GLN E 1 222 ? 173.370 161.053 151.168 1.00 25.97 ? 222 GLN E OE1 1 
ATOM 5486 N NE2 . GLN E 1 222 ? 174.397 162.431 149.725 1.00 30.01 ? 222 GLN E NE2 1 
ATOM 5487 N N   . ARG E 1 223 ? 168.351 159.323 148.857 1.00 26.00 ? 223 ARG E N   1 
ATOM 5488 C CA  . ARG E 1 223 ? 167.504 158.177 149.189 1.00 34.43 ? 223 ARG E CA  1 
ATOM 5489 C C   . ARG E 1 223 ? 168.197 156.931 148.646 1.00 30.07 ? 223 ARG E C   1 
ATOM 5490 O O   . ARG E 1 223 ? 168.181 156.687 147.435 1.00 23.53 ? 223 ARG E O   1 
ATOM 5491 C CB  . ARG E 1 223 ? 166.101 158.329 148.616 1.00 31.74 ? 223 ARG E CB  1 
ATOM 5492 C CG  . ARG E 1 223 ? 165.243 157.083 148.760 1.00 30.02 ? 223 ARG E CG  1 
ATOM 5493 C CD  . ARG E 1 223 ? 163.879 157.273 148.122 1.00 34.03 ? 223 ARG E CD  1 
ATOM 5494 N NE  . ARG E 1 223 ? 162.957 157.978 149.004 1.00 41.45 ? 223 ARG E NE  1 
ATOM 5495 C CZ  . ARG E 1 223 ? 162.191 157.389 149.911 1.00 40.46 ? 223 ARG E CZ  1 
ATOM 5496 N NH1 . ARG E 1 223 ? 162.211 156.078 150.086 1.00 32.84 ? 223 ARG E NH1 1 
ATOM 5497 N NH2 . ARG E 1 223 ? 161.386 158.135 150.663 1.00 38.48 ? 223 ARG E NH2 1 
ATOM 5498 N N   . GLU E 1 224 ? 168.804 156.154 149.546 1.00 37.17 ? 224 GLU E N   1 
ATOM 5499 C CA  . GLU E 1 224 ? 169.555 154.951 149.178 1.00 35.63 ? 224 GLU E CA  1 
ATOM 5500 C C   . GLU E 1 224 ? 170.642 155.272 148.156 1.00 31.88 ? 224 GLU E C   1 
ATOM 5501 O O   . GLU E 1 224 ? 170.918 154.487 147.247 1.00 30.40 ? 224 GLU E O   1 
ATOM 5502 C CB  . GLU E 1 224 ? 168.624 153.854 148.657 1.00 36.99 ? 224 GLU E CB  1 
ATOM 5503 C CG  . GLU E 1 224 ? 167.389 153.631 149.513 1.00 38.56 ? 224 GLU E CG  1 
ATOM 5504 C CD  . GLU E 1 224 ? 166.268 152.956 148.749 1.00 39.04 ? 224 GLU E CD  1 
ATOM 5505 O OE1 . GLU E 1 224 ? 166.563 152.100 147.890 1.00 44.99 ? 224 GLU E OE1 1 
ATOM 5506 O OE2 . GLU E 1 224 ? 165.090 153.284 149.006 1.00 37.17 ? 224 GLU E OE2 1 
ATOM 5507 N N   . SER E 1 225 ? 171.270 156.433 148.312 1.00 30.11 ? 225 SER E N   1 
ATOM 5508 C CA  . SER E 1 225 ? 172.244 156.940 147.362 1.00 28.70 ? 225 SER E CA  1 
ATOM 5509 C C   . SER E 1 225 ? 173.574 157.200 148.058 1.00 29.20 ? 225 SER E C   1 
ATOM 5510 O O   . SER E 1 225 ? 173.694 157.104 149.282 1.00 39.53 ? 225 SER E O   1 
ATOM 5511 C CB  . SER E 1 225 ? 171.735 158.221 146.690 1.00 30.27 ? 225 SER E CB  1 
ATOM 5512 O OG  . SER E 1 225 ? 170.538 157.978 145.972 1.00 37.64 ? 225 SER E OG  1 
ATOM 5513 N N   . GLN E 1 226 ? 174.584 157.529 147.257 1.00 33.40 ? 226 GLN E N   1 
ATOM 5514 C CA  . GLN E 1 226 ? 175.923 157.786 147.766 1.00 32.84 ? 226 GLN E CA  1 
ATOM 5515 C C   . GLN E 1 226 ? 176.491 159.032 147.106 1.00 32.49 ? 226 GLN E C   1 
ATOM 5516 O O   . GLN E 1 226 ? 176.312 159.244 145.902 1.00 32.50 ? 226 GLN E O   1 
ATOM 5517 C CB  . GLN E 1 226 ? 176.855 156.593 147.521 1.00 20.31 ? 226 GLN E CB  1 
ATOM 5518 C CG  . GLN E 1 226 ? 176.571 155.388 148.402 1.00 24.05 ? 226 GLN E CG  1 
ATOM 5519 C CD  . GLN E 1 226 ? 175.449 154.522 147.862 1.00 30.51 ? 226 GLN E CD  1 
ATOM 5520 O OE1 . GLN E 1 226 ? 175.302 154.363 146.650 1.00 31.21 ? 226 GLN E OE1 1 
ATOM 5521 N NE2 . GLN E 1 226 ? 174.649 153.963 148.760 1.00 34.29 ? 226 GLN E NE2 1 
ATOM 5522 N N   . ALA E 1 227 ? 177.171 159.856 147.901 1.00 24.60 ? 227 ALA E N   1 
ATOM 5523 C CA  . ALA E 1 227 ? 177.853 161.044 147.408 1.00 21.13 ? 227 ALA E CA  1 
ATOM 5524 C C   . ALA E 1 227 ? 179.270 161.057 147.957 1.00 27.62 ? 227 ALA E C   1 
ATOM 5525 O O   . ALA E 1 227 ? 179.471 160.910 149.167 1.00 26.65 ? 227 ALA E O   1 
ATOM 5526 C CB  . ALA E 1 227 ? 177.113 162.322 147.811 1.00 25.28 ? 227 ALA E CB  1 
ATOM 5527 N N   . TYR E 1 228 ? 180.247 161.233 147.071 1.00 37.96 ? 228 TYR E N   1 
ATOM 5528 C CA  . TYR E 1 228 ? 181.657 161.228 147.438 1.00 32.61 ? 228 TYR E CA  1 
ATOM 5529 C C   . TYR E 1 228 ? 182.269 162.566 147.051 1.00 28.12 ? 228 TYR E C   1 
ATOM 5530 O O   . TYR E 1 228 ? 182.217 162.961 145.882 1.00 41.58 ? 228 TYR E O   1 
ATOM 5531 C CB  . TYR E 1 228 ? 182.398 160.076 146.755 1.00 24.71 ? 228 TYR E CB  1 
ATOM 5532 C CG  . TYR E 1 228 ? 181.936 158.707 147.199 1.00 26.42 ? 228 TYR E CG  1 
ATOM 5533 C CD1 . TYR E 1 228 ? 180.806 158.122 146.645 1.00 24.15 ? 228 TYR E CD1 1 
ATOM 5534 C CD2 . TYR E 1 228 ? 182.631 158.002 148.172 1.00 29.54 ? 228 TYR E CD2 1 
ATOM 5535 C CE1 . TYR E 1 228 ? 180.380 156.871 147.049 1.00 30.89 ? 228 TYR E CE1 1 
ATOM 5536 C CE2 . TYR E 1 228 ? 182.213 156.750 148.580 1.00 32.18 ? 228 TYR E CE2 1 
ATOM 5537 C CZ  . TYR E 1 228 ? 181.086 156.191 148.016 1.00 30.31 ? 228 TYR E CZ  1 
ATOM 5538 O OH  . TYR E 1 228 ? 180.665 154.944 148.420 1.00 33.57 ? 228 TYR E OH  1 
ATOM 5539 N N   . TYR E 1 229 ? 182.851 163.253 148.028 1.00 21.12 ? 229 TYR E N   1 
ATOM 5540 C CA  . TYR E 1 229 ? 183.451 164.559 147.793 1.00 17.80 ? 229 TYR E CA  1 
ATOM 5541 C C   . TYR E 1 229 ? 184.963 164.510 147.980 1.00 24.83 ? 229 TYR E C   1 
ATOM 5542 O O   . TYR E 1 229 ? 185.454 164.127 149.041 1.00 35.68 ? 229 TYR E O   1 
ATOM 5543 C CB  . TYR E 1 229 ? 182.838 165.605 148.727 1.00 29.15 ? 229 TYR E CB  1 
ATOM 5544 C CG  . TYR E 1 229 ? 181.342 165.768 148.571 1.00 32.70 ? 229 TYR E CG  1 
ATOM 5545 C CD1 . TYR E 1 229 ? 180.814 166.686 147.673 1.00 25.81 ? 229 TYR E CD1 1 
ATOM 5546 C CD2 . TYR E 1 229 ? 180.459 165.006 149.324 1.00 26.63 ? 229 TYR E CD2 1 
ATOM 5547 C CE1 . TYR E 1 229 ? 179.449 166.838 147.527 1.00 23.56 ? 229 TYR E CE1 1 
ATOM 5548 C CE2 . TYR E 1 229 ? 179.092 165.150 149.185 1.00 23.50 ? 229 TYR E CE2 1 
ATOM 5549 C CZ  . TYR E 1 229 ? 178.592 166.068 148.286 1.00 31.98 ? 229 TYR E CZ  1 
ATOM 5550 O OH  . TYR E 1 229 ? 177.233 166.216 148.144 1.00 37.18 ? 229 TYR E OH  1 
# 
