data_9DM5
# 
_entry.id   9DM5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DM5         pdb_00009dm5 10.2210/pdb9dm5/pdb 
WWPDB D_1000288359 ?            ?                   
EMDB  EMD-46998    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DM5 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Product-Bound mannosyltransferase PimE' 
_pdbx_database_related.db_id          EMD-46998 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 6 
_pdbx_contact_author.email              fm123@cumc.columbia.edu 
_pdbx_contact_author.name_first         Filippo 
_pdbx_contact_author.name_last          Mancia 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3293-2200 
# 
_audit_author.name               'Liu, Y.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                3974 
_citation.page_last                 3974 
_citation.title                     'Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-57843-1 
_citation.pdbx_database_id_PubMed   40301322 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Liu, Y.'              1  0009-0007-2281-8160 
primary 'Brown, C.M.'          2  0000-0003-2006-5015 
primary 'Borges, N.'           3  0000-0002-3277-8517 
primary 'Nobre, R.N.'          4  ?                   
primary 'Erramilli, S.'        5  0000-0001-8694-7681 
primary 'Belcher Dufrisne, M.' 6  ?                   
primary 'Kloss, B.'            7  0000-0003-0130-8739 
primary 'Giacometti, S.'       8  0000-0002-8291-7722 
primary 'Esteves, A.M.'        9  ?                   
primary 'Timoteo, C.G.'        10 ?                   
primary 'Tokarz, P.'           11 ?                   
primary 'Cater, R.J.'          12 0000-0003-4503-002X 
primary 'Lowary, T.L.'         13 0000-0002-8331-8211 
primary 'Morita, Y.S.'         14 0000-0002-4514-9242 
primary 'Kossiakoff, A.A.'     15 0000-0003-3174-9359 
primary 'Santos, H.'           16 0000-0002-8050-9485 
primary 'Stansfeld, P.J.'      17 0000-0001-8800-7669 
primary 'Nygaard, R.'          18 0000-0002-0425-234X 
primary 'Mancia, F.'           19 0000-0003-3293-2200 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Mannosyltransferase 46068.090 1 ? ? ? ? 
2 non-polymer syn 
;(2S)-1-{[(S)-{[(1S,2R,3R,4S,5S,6R)-2-[(6-O-hexadecanoyl-beta-L-gulopyranosyl)oxy]-3,4,5-trihydroxy-6-{[beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->6)-beta-D-mannopyranosyl-(1->6)-alpha-D-mannopyranosyl]oxy}cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}-3-(hexadecanoyloxy)propan-2-yl 10-methyloctadecanoate
;
1841.747  1 ? ? ? ? 
3 non-polymer syn 'MONO-TRANS, OCTA-CIS DECAPRENYL-PHOSPHATE' 779.165   1 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLHVYVSGPATLGHGNLYEFTYP
DKTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLD
YGQINVLLMLLILLAVASSRWWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYF
TDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDRLGQICVVEMFGLLISPISWT
HHWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVV
GRRSGHLGRLPWRHV
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLHVYVSGPATLGHGNLYEFTYP
DKTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLD
YGQINVLLMLLILLAVASSRWWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYF
TDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDRLGQICVVEMFGLLISPISWT
HHWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVV
GRRSGHLGRLPWRHV
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;(2S)-1-{[(S)-{[(1S,2R,3R,4S,5S,6R)-2-[(6-O-hexadecanoyl-beta-L-gulopyranosyl)oxy]-3,4,5-trihydroxy-6-{[beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->6)-beta-D-mannopyranosyl-(1->6)-alpha-D-mannopyranosyl]oxy}cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}-3-(hexadecanoyloxy)propan-2-yl 10-methyloctadecanoate
;
A1A8B 
3 'MONO-TRANS, OCTA-CIS DECAPRENYL-PHOSPHATE' DSL   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   THR n 
1 4   GLU n 
1 5   LYS n 
1 6   THR n 
1 7   GLU n 
1 8   PRO n 
1 9   THR n 
1 10  ARG n 
1 11  ALA n 
1 12  ASN n 
1 13  VAL n 
1 14  GLU n 
1 15  PRO n 
1 16  PRO n 
1 17  MET n 
1 18  PRO n 
1 19  THR n 
1 20  ARG n 
1 21  GLY n 
1 22  ALA n 
1 23  SER n 
1 24  ALA n 
1 25  TRP n 
1 26  ARG n 
1 27  ARG n 
1 28  VAL n 
1 29  ARG n 
1 30  ALA n 
1 31  TRP n 
1 32  GLY n 
1 33  PRO n 
1 34  TRP n 
1 35  LEU n 
1 36  LEU n 
1 37  GLY n 
1 38  LEU n 
1 39  SER n 
1 40  VAL n 
1 41  ALA n 
1 42  VAL n 
1 43  ARG n 
1 44  LEU n 
1 45  ALA n 
1 46  TRP n 
1 47  ALA n 
1 48  TYR n 
1 49  LEU n 
1 50  THR n 
1 51  PRO n 
1 52  HIS n 
1 53  GLY n 
1 54  ALA n 
1 55  ASP n 
1 56  LEU n 
1 57  VAL n 
1 58  ASP n 
1 59  LEU n 
1 60  HIS n 
1 61  VAL n 
1 62  TYR n 
1 63  VAL n 
1 64  SER n 
1 65  GLY n 
1 66  PRO n 
1 67  ALA n 
1 68  THR n 
1 69  LEU n 
1 70  GLY n 
1 71  HIS n 
1 72  GLY n 
1 73  ASN n 
1 74  LEU n 
1 75  TYR n 
1 76  GLU n 
1 77  PHE n 
1 78  THR n 
1 79  TYR n 
1 80  PRO n 
1 81  ASP n 
1 82  LYS n 
1 83  THR n 
1 84  PRO n 
1 85  ASP n 
1 86  PHE n 
1 87  PRO n 
1 88  LEU n 
1 89  PRO n 
1 90  PHE n 
1 91  THR n 
1 92  TYR n 
1 93  PRO n 
1 94  PRO n 
1 95  PHE n 
1 96  ALA n 
1 97  ALA n 
1 98  VAL n 
1 99  VAL n 
1 100 PHE n 
1 101 TRP n 
1 102 PRO n 
1 103 LEU n 
1 104 HIS n 
1 105 LEU n 
1 106 ILE n 
1 107 PRO n 
1 108 PHE n 
1 109 THR n 
1 110 LEU n 
1 111 LEU n 
1 112 GLY n 
1 113 LEU n 
1 114 CYS n 
1 115 TRP n 
1 116 ILE n 
1 117 LEU n 
1 118 GLY n 
1 119 THR n 
1 120 ILE n 
1 121 ALA n 
1 122 ALA n 
1 123 LEU n 
1 124 TYR n 
1 125 ALA n 
1 126 VAL n 
1 127 VAL n 
1 128 ARG n 
1 129 LEU n 
1 130 SER n 
1 131 GLN n 
1 132 ARG n 
1 133 LEU n 
1 134 LEU n 
1 135 GLY n 
1 136 PHE n 
1 137 ASP n 
1 138 ASP n 
1 139 ALA n 
1 140 ARG n 
1 141 ALA n 
1 142 ALA n 
1 143 ALA n 
1 144 VAL n 
1 145 TRP n 
1 146 THR n 
1 147 ALA n 
1 148 VAL n 
1 149 THR n 
1 150 MET n 
1 151 TRP n 
1 152 THR n 
1 153 GLU n 
1 154 PRO n 
1 155 VAL n 
1 156 ARG n 
1 157 SER n 
1 158 THR n 
1 159 LEU n 
1 160 ASP n 
1 161 TYR n 
1 162 GLY n 
1 163 GLN n 
1 164 ILE n 
1 165 ASN n 
1 166 VAL n 
1 167 LEU n 
1 168 LEU n 
1 169 MET n 
1 170 LEU n 
1 171 LEU n 
1 172 ILE n 
1 173 LEU n 
1 174 LEU n 
1 175 ALA n 
1 176 VAL n 
1 177 ALA n 
1 178 SER n 
1 179 SER n 
1 180 ARG n 
1 181 TRP n 
1 182 TRP n 
1 183 ILE n 
1 184 SER n 
1 185 GLY n 
1 186 THR n 
1 187 LEU n 
1 188 ILE n 
1 189 GLY n 
1 190 LEU n 
1 191 ALA n 
1 192 GLY n 
1 193 GLY n 
1 194 VAL n 
1 195 LYS n 
1 196 LEU n 
1 197 THR n 
1 198 PRO n 
1 199 LEU n 
1 200 VAL n 
1 201 SER n 
1 202 GLY n 
1 203 LEU n 
1 204 TYR n 
1 205 PHE n 
1 206 LEU n 
1 207 GLY n 
1 208 ALA n 
1 209 ARG n 
1 210 ARG n 
1 211 TRP n 
1 212 THR n 
1 213 THR n 
1 214 ALA n 
1 215 ILE n 
1 216 TRP n 
1 217 ALA n 
1 218 GLY n 
1 219 VAL n 
1 220 VAL n 
1 221 PHE n 
1 222 LEU n 
1 223 LEU n 
1 224 THR n 
1 225 VAL n 
1 226 VAL n 
1 227 VAL n 
1 228 GLY n 
1 229 ILE n 
1 230 ALA n 
1 231 VAL n 
1 232 VAL n 
1 233 GLY n 
1 234 GLU n 
1 235 GLN n 
1 236 GLY n 
1 237 ARG n 
1 238 TYR n 
1 239 TYR n 
1 240 PHE n 
1 241 THR n 
1 242 ASP n 
1 243 LEU n 
1 244 LEU n 
1 245 GLY n 
1 246 LYS n 
1 247 PRO n 
1 248 ASP n 
1 249 ARG n 
1 250 ILE n 
1 251 GLY n 
1 252 PRO n 
1 253 ILE n 
1 254 ALA n 
1 255 THR n 
1 256 VAL n 
1 257 PHE n 
1 258 ASN n 
1 259 GLN n 
1 260 SER n 
1 261 TRP n 
1 262 ARG n 
1 263 GLY n 
1 264 GLY n 
1 265 ILE n 
1 266 SER n 
1 267 ARG n 
1 268 ILE n 
1 269 LEU n 
1 270 GLY n 
1 271 HIS n 
1 272 ASP n 
1 273 ALA n 
1 274 GLY n 
1 275 SER n 
1 276 GLY n 
1 277 VAL n 
1 278 LEU n 
1 279 VAL n 
1 280 LEU n 
1 281 PHE n 
1 282 ALA n 
1 283 TYR n 
1 284 ALA n 
1 285 VAL n 
1 286 THR n 
1 287 ALA n 
1 288 ILE n 
1 289 LEU n 
1 290 ALA n 
1 291 PHE n 
1 292 LEU n 
1 293 ALA n 
1 294 TRP n 
1 295 ARG n 
1 296 ALA n 
1 297 VAL n 
1 298 ASN n 
1 299 ASP n 
1 300 ARG n 
1 301 LEU n 
1 302 GLY n 
1 303 GLN n 
1 304 ILE n 
1 305 CYS n 
1 306 VAL n 
1 307 VAL n 
1 308 GLU n 
1 309 MET n 
1 310 PHE n 
1 311 GLY n 
1 312 LEU n 
1 313 LEU n 
1 314 ILE n 
1 315 SER n 
1 316 PRO n 
1 317 ILE n 
1 318 SER n 
1 319 TRP n 
1 320 THR n 
1 321 HIS n 
1 322 HIS n 
1 323 TRP n 
1 324 VAL n 
1 325 TRP n 
1 326 MET n 
1 327 VAL n 
1 328 PRO n 
1 329 PHE n 
1 330 MET n 
1 331 VAL n 
1 332 TRP n 
1 333 LEU n 
1 334 LEU n 
1 335 HIS n 
1 336 GLY n 
1 337 PRO n 
1 338 TRP n 
1 339 ARG n 
1 340 ASP n 
1 341 LYS n 
1 342 VAL n 
1 343 GLY n 
1 344 ALA n 
1 345 LYS n 
1 346 VAL n 
1 347 PHE n 
1 348 GLY n 
1 349 CYS n 
1 350 GLY n 
1 351 TRP n 
1 352 LEU n 
1 353 VAL n 
1 354 LEU n 
1 355 LEU n 
1 356 LEU n 
1 357 ILE n 
1 358 GLY n 
1 359 VAL n 
1 360 PRO n 
1 361 TRP n 
1 362 LEU n 
1 363 LEU n 
1 364 SER n 
1 365 PHE n 
1 366 ALA n 
1 367 GLN n 
1 368 PRO n 
1 369 ASP n 
1 370 ILE n 
1 371 TRP n 
1 372 ARG n 
1 373 ILE n 
1 374 ASP n 
1 375 ARG n 
1 376 PRO n 
1 377 TRP n 
1 378 PRO n 
1 379 LEU n 
1 380 ALA n 
1 381 TRP n 
1 382 ALA n 
1 383 GLY n 
1 384 LEU n 
1 385 VAL n 
1 386 ASP n 
1 387 ILE n 
1 388 VAL n 
1 389 ALA n 
1 390 ALA n 
1 391 ILE n 
1 392 ALA n 
1 393 THR n 
1 394 LEU n 
1 395 THR n 
1 396 TRP n 
1 397 MET n 
1 398 ALA n 
1 399 VAL n 
1 400 VAL n 
1 401 GLY n 
1 402 ARG n 
1 403 ARG n 
1 404 SER n 
1 405 GLY n 
1 406 HIS n 
1 407 LEU n 
1 408 GLY n 
1 409 ARG n 
1 410 LEU n 
1 411 PRO n 
1 412 TRP n 
1 413 ARG n 
1 414 HIS n 
1 415 VAL n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   415 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 D2E76_03800 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Mycobacteroides abscessus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     36809 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1A8B non-polymer         . 
;(2S)-1-{[(S)-{[(1S,2R,3R,4S,5S,6R)-2-[(6-O-hexadecanoyl-beta-L-gulopyranosyl)oxy]-3,4,5-trihydroxy-6-{[beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->6)-beta-D-mannopyranosyl-(1->6)-alpha-D-mannopyranosyl]oxy}cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}-3-(hexadecanoyloxy)propan-2-yl 10-methyloctadecanoate
;
? 'C90 H105 O39 P' 1841.747 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093   
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209  
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118  
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103  
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158  
DSL   non-polymer         . 'MONO-TRANS, OCTA-CIS DECAPRENYL-PHOSPHATE' ? 'C50 H83 O4 P'   779.165  
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144  
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129  
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067   
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173  
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173  
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195  
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211  
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189  
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130  
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093  
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119  
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225  
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189  
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   THR 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   LYS 5   5   ?   ?   ?   A . n 
A 1 6   THR 6   6   ?   ?   ?   A . n 
A 1 7   GLU 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  ARG 10  10  ?   ?   ?   A . n 
A 1 11  ALA 11  11  ?   ?   ?   A . n 
A 1 12  ASN 12  12  ?   ?   ?   A . n 
A 1 13  VAL 13  13  ?   ?   ?   A . n 
A 1 14  GLU 14  14  ?   ?   ?   A . n 
A 1 15  PRO 15  15  ?   ?   ?   A . n 
A 1 16  PRO 16  16  ?   ?   ?   A . n 
A 1 17  MET 17  17  ?   ?   ?   A . n 
A 1 18  PRO 18  18  ?   ?   ?   A . n 
A 1 19  THR 19  19  ?   ?   ?   A . n 
A 1 20  ARG 20  20  ?   ?   ?   A . n 
A 1 21  GLY 21  21  21  GLY GLY A . n 
A 1 22  ALA 22  22  22  ALA ALA A . n 
A 1 23  SER 23  23  23  SER SER A . n 
A 1 24  ALA 24  24  24  ALA ALA A . n 
A 1 25  TRP 25  25  25  TRP TRP A . n 
A 1 26  ARG 26  26  26  ARG ARG A . n 
A 1 27  ARG 27  27  27  ARG ARG A . n 
A 1 28  VAL 28  28  28  VAL VAL A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  ALA 30  30  30  ALA ALA A . n 
A 1 31  TRP 31  31  31  TRP TRP A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  PRO 33  33  33  PRO PRO A . n 
A 1 34  TRP 34  34  34  TRP TRP A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  GLY 37  37  37  GLY GLY A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  VAL 40  40  40  VAL VAL A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  ARG 43  43  43  ARG ARG A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  ALA 45  45  45  ALA ALA A . n 
A 1 46  TRP 46  46  46  TRP TRP A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  TYR 48  48  48  TYR TYR A . n 
A 1 49  LEU 49  49  49  LEU LEU A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  PRO 51  51  51  PRO PRO A . n 
A 1 52  HIS 52  52  52  HIS HIS A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  ASP 55  55  55  ASP ASP A . n 
A 1 56  LEU 56  56  56  LEU LEU A . n 
A 1 57  VAL 57  57  57  VAL VAL A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  HIS 60  60  60  HIS HIS A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  TYR 62  62  62  TYR TYR A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  SER 64  64  64  SER SER A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  PRO 66  66  66  PRO PRO A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  LEU 69  69  69  LEU LEU A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  HIS 71  71  71  HIS HIS A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  ASN 73  73  73  ASN ASN A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  TYR 75  75  75  TYR TYR A . n 
A 1 76  GLU 76  76  76  GLU GLU A . n 
A 1 77  PHE 77  77  77  PHE PHE A . n 
A 1 78  THR 78  78  78  THR THR A . n 
A 1 79  TYR 79  79  79  TYR TYR A . n 
A 1 80  PRO 80  80  80  PRO PRO A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  LYS 82  82  82  LYS LYS A . n 
A 1 83  THR 83  83  83  THR THR A . n 
A 1 84  PRO 84  84  84  PRO PRO A . n 
A 1 85  ASP 85  85  85  ASP ASP A . n 
A 1 86  PHE 86  86  86  PHE PHE A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  PHE 90  90  90  PHE PHE A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  TYR 92  92  92  TYR TYR A . n 
A 1 93  PRO 93  93  93  PRO PRO A . n 
A 1 94  PRO 94  94  94  PRO PRO A . n 
A 1 95  PHE 95  95  95  PHE PHE A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  VAL 98  98  98  VAL VAL A . n 
A 1 99  VAL 99  99  99  VAL VAL A . n 
A 1 100 PHE 100 100 100 PHE PHE A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 PRO 102 102 102 PRO PRO A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 HIS 104 104 104 HIS HIS A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 PRO 107 107 107 PRO PRO A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 THR 109 109 109 THR THR A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 GLY 112 112 112 GLY GLY A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 CYS 114 114 114 CYS CYS A . n 
A 1 115 TRP 115 115 115 TRP TRP A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 LEU 117 117 117 LEU LEU A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 THR 119 119 119 THR THR A . n 
A 1 120 ILE 120 120 120 ILE ILE A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 TYR 124 124 124 TYR TYR A . n 
A 1 125 ALA 125 125 125 ALA ALA A . n 
A 1 126 VAL 126 126 126 VAL VAL A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 ARG 128 128 128 ARG ARG A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 SER 130 130 130 SER SER A . n 
A 1 131 GLN 131 131 131 GLN GLN A . n 
A 1 132 ARG 132 132 132 ARG ARG A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 GLY 135 135 135 GLY GLY A . n 
A 1 136 PHE 136 136 136 PHE PHE A . n 
A 1 137 ASP 137 137 137 ASP ASP A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 ALA 139 139 139 ALA ALA A . n 
A 1 140 ARG 140 140 140 ARG ARG A . n 
A 1 141 ALA 141 141 141 ALA ALA A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 VAL 144 144 144 VAL VAL A . n 
A 1 145 TRP 145 145 145 TRP TRP A . n 
A 1 146 THR 146 146 146 THR THR A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 THR 149 149 149 THR THR A . n 
A 1 150 MET 150 150 150 MET MET A . n 
A 1 151 TRP 151 151 151 TRP TRP A . n 
A 1 152 THR 152 152 152 THR THR A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 PRO 154 154 154 PRO PRO A . n 
A 1 155 VAL 155 155 155 VAL VAL A . n 
A 1 156 ARG 156 156 156 ARG ARG A . n 
A 1 157 SER 157 157 157 SER SER A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 TYR 161 161 161 TYR TYR A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 GLN 163 163 163 GLN GLN A . n 
A 1 164 ILE 164 164 164 ILE ILE A . n 
A 1 165 ASN 165 165 165 ASN ASN A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 MET 169 169 169 MET MET A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 LEU 174 174 174 LEU LEU A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 ALA 177 177 177 ALA ALA A . n 
A 1 178 SER 178 178 178 SER SER A . n 
A 1 179 SER 179 179 179 SER SER A . n 
A 1 180 ARG 180 180 180 ARG ARG A . n 
A 1 181 TRP 181 181 181 TRP TRP A . n 
A 1 182 TRP 182 182 182 TRP TRP A . n 
A 1 183 ILE 183 183 183 ILE ILE A . n 
A 1 184 SER 184 184 184 SER SER A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 THR 186 186 186 THR THR A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 ILE 188 188 188 ILE ILE A . n 
A 1 189 GLY 189 189 189 GLY GLY A . n 
A 1 190 LEU 190 190 190 LEU LEU A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 GLY 192 192 192 GLY GLY A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 LYS 195 195 195 LYS LYS A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 THR 197 197 197 THR THR A . n 
A 1 198 PRO 198 198 198 PRO PRO A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 VAL 200 200 200 VAL VAL A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 LEU 203 203 203 LEU LEU A . n 
A 1 204 TYR 204 204 204 TYR TYR A . n 
A 1 205 PHE 205 205 205 PHE PHE A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 GLY 207 207 207 GLY GLY A . n 
A 1 208 ALA 208 208 208 ALA ALA A . n 
A 1 209 ARG 209 209 209 ARG ARG A . n 
A 1 210 ARG 210 210 210 ARG ARG A . n 
A 1 211 TRP 211 211 211 TRP TRP A . n 
A 1 212 THR 212 212 212 THR THR A . n 
A 1 213 THR 213 213 213 THR THR A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 ILE 215 215 215 ILE ILE A . n 
A 1 216 TRP 216 216 216 TRP TRP A . n 
A 1 217 ALA 217 217 217 ALA ALA A . n 
A 1 218 GLY 218 218 218 GLY GLY A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 VAL 220 220 220 VAL VAL A . n 
A 1 221 PHE 221 221 221 PHE PHE A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 VAL 227 227 227 VAL VAL A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 ILE 229 229 229 ILE ILE A . n 
A 1 230 ALA 230 230 230 ALA ALA A . n 
A 1 231 VAL 231 231 231 VAL VAL A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 GLN 235 235 235 GLN GLN A . n 
A 1 236 GLY 236 236 236 GLY GLY A . n 
A 1 237 ARG 237 237 237 ARG ARG A . n 
A 1 238 TYR 238 238 238 TYR TYR A . n 
A 1 239 TYR 239 239 239 TYR TYR A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 THR 241 241 241 THR THR A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 GLY 245 245 245 GLY GLY A . n 
A 1 246 LYS 246 246 246 LYS LYS A . n 
A 1 247 PRO 247 247 247 PRO PRO A . n 
A 1 248 ASP 248 248 248 ASP ASP A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 ILE 250 250 250 ILE ILE A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 PRO 252 252 252 PRO PRO A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 ASN 258 258 258 ASN ASN A . n 
A 1 259 GLN 259 259 259 GLN GLN A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 TRP 261 261 261 TRP TRP A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 GLY 263 263 263 GLY GLY A . n 
A 1 264 GLY 264 264 264 GLY GLY A . n 
A 1 265 ILE 265 265 265 ILE ILE A . n 
A 1 266 SER 266 266 266 SER SER A . n 
A 1 267 ARG 267 267 267 ARG ARG A . n 
A 1 268 ILE 268 268 268 ILE ILE A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 GLY 270 270 270 GLY GLY A . n 
A 1 271 HIS 271 271 271 HIS HIS A . n 
A 1 272 ASP 272 272 272 ASP ASP A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 GLY 274 274 274 GLY GLY A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 GLY 276 276 276 GLY GLY A . n 
A 1 277 VAL 277 277 277 VAL VAL A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 VAL 279 279 279 VAL VAL A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 TYR 283 283 283 TYR TYR A . n 
A 1 284 ALA 284 284 284 ALA ALA A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 THR 286 286 286 THR THR A . n 
A 1 287 ALA 287 287 287 ALA ALA A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 ALA 290 290 290 ALA ALA A . n 
A 1 291 PHE 291 291 291 PHE PHE A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 TRP 294 294 294 TRP TRP A . n 
A 1 295 ARG 295 295 295 ARG ARG A . n 
A 1 296 ALA 296 296 296 ALA ALA A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 ASN 298 298 298 ASN ASN A . n 
A 1 299 ASP 299 299 299 ASP ASP A . n 
A 1 300 ARG 300 300 300 ARG ARG A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 GLN 303 303 303 GLN GLN A . n 
A 1 304 ILE 304 304 304 ILE ILE A . n 
A 1 305 CYS 305 305 305 CYS CYS A . n 
A 1 306 VAL 306 306 306 VAL VAL A . n 
A 1 307 VAL 307 307 307 VAL VAL A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 MET 309 309 309 MET MET A . n 
A 1 310 PHE 310 310 310 PHE PHE A . n 
A 1 311 GLY 311 311 311 GLY GLY A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 LEU 313 313 313 LEU LEU A . n 
A 1 314 ILE 314 314 314 ILE ILE A . n 
A 1 315 SER 315 315 315 SER SER A . n 
A 1 316 PRO 316 316 316 PRO PRO A . n 
A 1 317 ILE 317 317 317 ILE ILE A . n 
A 1 318 SER 318 318 318 SER SER A . n 
A 1 319 TRP 319 319 319 TRP TRP A . n 
A 1 320 THR 320 320 320 THR THR A . n 
A 1 321 HIS 321 321 321 HIS HIS A . n 
A 1 322 HIS 322 322 322 HIS HIS A . n 
A 1 323 TRP 323 323 323 TRP TRP A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 TRP 325 325 325 TRP TRP A . n 
A 1 326 MET 326 326 326 MET MET A . n 
A 1 327 VAL 327 327 327 VAL VAL A . n 
A 1 328 PRO 328 328 328 PRO PRO A . n 
A 1 329 PHE 329 329 329 PHE PHE A . n 
A 1 330 MET 330 330 330 MET MET A . n 
A 1 331 VAL 331 331 331 VAL VAL A . n 
A 1 332 TRP 332 332 332 TRP TRP A . n 
A 1 333 LEU 333 333 333 LEU LEU A . n 
A 1 334 LEU 334 334 334 LEU LEU A . n 
A 1 335 HIS 335 335 335 HIS HIS A . n 
A 1 336 GLY 336 336 336 GLY GLY A . n 
A 1 337 PRO 337 337 337 PRO PRO A . n 
A 1 338 TRP 338 338 338 TRP TRP A . n 
A 1 339 ARG 339 339 339 ARG ARG A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 LYS 341 341 341 LYS LYS A . n 
A 1 342 VAL 342 342 342 VAL VAL A . n 
A 1 343 GLY 343 343 343 GLY GLY A . n 
A 1 344 ALA 344 344 344 ALA ALA A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 GLY 348 348 348 GLY GLY A . n 
A 1 349 CYS 349 349 349 CYS CYS A . n 
A 1 350 GLY 350 350 350 GLY GLY A . n 
A 1 351 TRP 351 351 351 TRP TRP A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 VAL 353 353 353 VAL VAL A . n 
A 1 354 LEU 354 354 354 LEU LEU A . n 
A 1 355 LEU 355 355 355 LEU LEU A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 GLY 358 358 358 GLY GLY A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 PRO 360 360 360 PRO PRO A . n 
A 1 361 TRP 361 361 361 TRP TRP A . n 
A 1 362 LEU 362 362 362 LEU LEU A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 SER 364 364 364 SER SER A . n 
A 1 365 PHE 365 365 365 PHE PHE A . n 
A 1 366 ALA 366 366 366 ALA ALA A . n 
A 1 367 GLN 367 367 367 GLN GLN A . n 
A 1 368 PRO 368 368 368 PRO PRO A . n 
A 1 369 ASP 369 369 369 ASP ASP A . n 
A 1 370 ILE 370 370 370 ILE ILE A . n 
A 1 371 TRP 371 371 371 TRP TRP A . n 
A 1 372 ARG 372 372 372 ARG ARG A . n 
A 1 373 ILE 373 373 373 ILE ILE A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 ARG 375 375 375 ARG ARG A . n 
A 1 376 PRO 376 376 376 PRO PRO A . n 
A 1 377 TRP 377 377 377 TRP TRP A . n 
A 1 378 PRO 378 378 378 PRO PRO A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 ALA 380 380 380 ALA ALA A . n 
A 1 381 TRP 381 381 381 TRP TRP A . n 
A 1 382 ALA 382 382 382 ALA ALA A . n 
A 1 383 GLY 383 383 383 GLY GLY A . n 
A 1 384 LEU 384 384 384 LEU LEU A . n 
A 1 385 VAL 385 385 385 VAL VAL A . n 
A 1 386 ASP 386 386 386 ASP ASP A . n 
A 1 387 ILE 387 387 387 ILE ILE A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 ALA 389 389 389 ALA ALA A . n 
A 1 390 ALA 390 390 390 ALA ALA A . n 
A 1 391 ILE 391 391 391 ILE ILE A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 THR 393 393 393 THR THR A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 THR 395 395 395 THR THR A . n 
A 1 396 TRP 396 396 396 TRP TRP A . n 
A 1 397 MET 397 397 397 MET MET A . n 
A 1 398 ALA 398 398 398 ALA ALA A . n 
A 1 399 VAL 399 399 399 VAL VAL A . n 
A 1 400 VAL 400 400 400 VAL VAL A . n 
A 1 401 GLY 401 401 401 GLY GLY A . n 
A 1 402 ARG 402 402 402 ARG ARG A . n 
A 1 403 ARG 403 403 403 ARG ARG A . n 
A 1 404 SER 404 404 ?   ?   ?   A . n 
A 1 405 GLY 405 405 ?   ?   ?   A . n 
A 1 406 HIS 406 406 ?   ?   ?   A . n 
A 1 407 LEU 407 407 ?   ?   ?   A . n 
A 1 408 GLY 408 408 ?   ?   ?   A . n 
A 1 409 ARG 409 409 ?   ?   ?   A . n 
A 1 410 LEU 410 410 ?   ?   ?   A . n 
A 1 411 PRO 411 411 ?   ?   ?   A . n 
A 1 412 TRP 412 412 ?   ?   ?   A . n 
A 1 413 ARG 413 413 ?   ?   ?   A . n 
A 1 414 HIS 414 414 ?   ?   ?   A . n 
A 1 415 VAL 415 415 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1A8B 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1A8B 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1A8B 1 501 502 A1A8B LIG A . 
C 3 DSL   1 502 503 DSL   LIG A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 N 1 A A1A8B 501 ? C41 ? B A1A8B 1 C41 
2  1 N 1 A A1A8B 501 ? C42 ? B A1A8B 1 C42 
3  1 N 1 A A1A8B 501 ? C43 ? B A1A8B 1 C43 
4  1 N 1 A A1A8B 501 ? C44 ? B A1A8B 1 C44 
5  1 N 1 A A1A8B 501 ? C45 ? B A1A8B 1 C45 
6  1 N 1 A A1A8B 501 ? C46 ? B A1A8B 1 C46 
7  1 N 1 A A1A8B 501 ? C47 ? B A1A8B 1 C47 
8  1 N 1 A A1A8B 501 ? C48 ? B A1A8B 1 C48 
9  1 N 1 A A1A8B 501 ? C49 ? B A1A8B 1 C49 
10 1 N 1 A A1A8B 501 ? C50 ? B A1A8B 1 C50 
11 1 N 1 A A1A8B 501 ? C51 ? B A1A8B 1 C51 
12 1 N 1 A A1A8B 501 ? C52 ? B A1A8B 1 C52 
13 1 N 1 A A1A8B 501 ? C53 ? B A1A8B 1 C53 
14 1 N 1 A A1A8B 501 ? C54 ? B A1A8B 1 C54 
15 1 N 1 A A1A8B 501 ? O38 ? B A1A8B 1 O38 
16 1 N 1 A A1A8B 501 ? C56 ? B A1A8B 1 C56 
17 1 N 1 A A1A8B 501 ? O36 ? B A1A8B 1 O36 
18 1 N 1 A A1A8B 501 ? C58 ? B A1A8B 1 C58 
19 1 N 1 A A1A8B 501 ? C57 ? B A1A8B 1 C57 
20 1 N 1 A A1A8B 501 ? C59 ? B A1A8B 1 C59 
21 1 N 1 A A1A8B 501 ? O37 ? B A1A8B 1 O37 
22 1 N 1 A A1A8B 501 ? C55 ? B A1A8B 1 C55 
23 1 N 1 A A1A8B 501 ? C60 ? B A1A8B 1 C60 
24 1 N 1 A A1A8B 501 ? C61 ? B A1A8B 1 C61 
25 1 N 1 A A1A8B 501 ? C62 ? B A1A8B 1 C62 
26 1 N 1 A A1A8B 501 ? C63 ? B A1A8B 1 C63 
27 1 N 1 A A1A8B 501 ? C64 ? B A1A8B 1 C64 
28 1 N 1 A A1A8B 501 ? C65 ? B A1A8B 1 C65 
29 1 N 1 A A1A8B 501 ? C66 ? B A1A8B 1 C66 
30 1 N 1 A A1A8B 501 ? C67 ? B A1A8B 1 C67 
31 1 N 1 A A1A8B 501 ? C68 ? B A1A8B 1 C68 
32 1 N 1 A A1A8B 501 ? C69 ? B A1A8B 1 C69 
33 1 N 1 A A1A8B 501 ? C70 ? B A1A8B 1 C70 
34 1 N 1 A A1A8B 501 ? C71 ? B A1A8B 1 C71 
35 1 N 1 A A1A8B 501 ? C72 ? B A1A8B 1 C72 
36 1 N 1 A A1A8B 501 ? C73 ? B A1A8B 1 C73 
37 1 N 1 A A1A8B 501 ? O39 ? B A1A8B 1 O39 
38 1 N 1 A A1A8B 501 ? C74 ? B A1A8B 1 C74 
39 1 N 1 A A1A8B 501 ? C75 ? B A1A8B 1 C75 
40 1 N 1 A A1A8B 501 ? C76 ? B A1A8B 1 C76 
41 1 N 1 A A1A8B 501 ? C77 ? B A1A8B 1 C77 
42 1 N 1 A A1A8B 501 ? C78 ? B A1A8B 1 C78 
43 1 N 1 A A1A8B 501 ? C79 ? B A1A8B 1 C79 
44 1 N 1 A A1A8B 501 ? C80 ? B A1A8B 1 C80 
45 1 N 1 A A1A8B 501 ? C81 ? B A1A8B 1 C81 
46 1 N 1 A A1A8B 501 ? C82 ? B A1A8B 1 C82 
47 1 N 1 A A1A8B 501 ? C83 ? B A1A8B 1 C83 
48 1 N 1 A A1A8B 501 ? C84 ? B A1A8B 1 C84 
49 1 N 1 A A1A8B 501 ? C85 ? B A1A8B 1 C85 
50 1 N 1 A A1A8B 501 ? C86 ? B A1A8B 1 C86 
51 1 N 1 A A1A8B 501 ? C87 ? B A1A8B 1 C87 
52 1 N 1 A A1A8B 501 ? C88 ? B A1A8B 1 C88 
53 1 N 1 A A1A8B 501 ? C89 ? B A1A8B 1 C89 
54 1 N 1 A A1A8B 501 ? C90 ? B A1A8B 1 C90 
55 1 N 1 A DSL   502 ? C06 ? C DSL   1 C06 
56 1 N 1 A DSL   502 ? C07 ? C DSL   1 C07 
57 1 N 1 A DSL   502 ? C08 ? C DSL   1 C08 
58 1 N 1 A DSL   502 ? C09 ? C DSL   1 C09 
59 1 N 1 A DSL   502 ? C10 ? C DSL   1 C10 
60 1 N 1 A DSL   502 ? C11 ? C DSL   1 C11 
61 1 N 1 A DSL   502 ? C12 ? C DSL   1 C12 
62 1 N 1 A DSL   502 ? C13 ? C DSL   1 C13 
63 1 N 1 A DSL   502 ? C14 ? C DSL   1 C14 
64 1 N 1 A DSL   502 ? C15 ? C DSL   1 C15 
65 1 N 1 A DSL   502 ? C16 ? C DSL   1 C16 
66 1 N 1 A DSL   502 ? C17 ? C DSL   1 C17 
67 1 N 1 A DSL   502 ? C18 ? C DSL   1 C18 
68 1 N 1 A DSL   502 ? C19 ? C DSL   1 C19 
69 1 N 1 A DSL   502 ? C20 ? C DSL   1 C20 
70 1 N 1 A DSL   502 ? C21 ? C DSL   1 C21 
71 1 N 1 A DSL   502 ? C22 ? C DSL   1 C22 
72 1 N 1 A DSL   502 ? C23 ? C DSL   1 C23 
73 1 N 1 A DSL   502 ? C24 ? C DSL   1 C24 
74 1 N 1 A DSL   502 ? C25 ? C DSL   1 C25 
75 1 N 1 A DSL   502 ? C26 ? C DSL   1 C26 
76 1 N 1 A DSL   502 ? C27 ? C DSL   1 C27 
77 1 N 1 A DSL   502 ? C28 ? C DSL   1 C28 
78 1 N 1 A DSL   502 ? C29 ? C DSL   1 C29 
79 1 N 1 A DSL   502 ? C30 ? C DSL   1 C30 
80 1 N 1 A DSL   502 ? C31 ? C DSL   1 C31 
81 1 N 1 A DSL   502 ? C32 ? C DSL   1 C32 
82 1 N 1 A DSL   502 ? C33 ? C DSL   1 C33 
83 1 N 1 A DSL   502 ? C34 ? C DSL   1 C34 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DM5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DM5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DM5 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9DM5 
_struct.title                        'Product-Bound mannosyltransferase PimE' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DM5 
_struct_keywords.text            'mannosyltransferase, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A418LCK8_9MYCO 
_struct_ref.pdbx_db_accession          A0A418LCK8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLHVYVSGPATLGHGNLYEFTYP
DKTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLD
YGQINVLLMLLILLAVASSRWWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYF
TDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDRLGQICVVEMFGLLISPISWT
HHWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVV
GRRSGHLGRLPWRHV
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9DM5 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 415 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A418LCK8 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  415 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       415 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 21  ? TRP A 31  ? GLY A 21  TRP A 31  1 ? 11 
HELX_P HELX_P2  AA2 GLY A 32  ? THR A 50  ? GLY A 32  THR A 50  1 ? 19 
HELX_P HELX_P3  AA3 LEU A 56  ? GLY A 65  ? LEU A 56  GLY A 65  1 ? 10 
HELX_P HELX_P4  AA4 PRO A 66  ? LEU A 69  ? PRO A 66  LEU A 69  5 ? 4  
HELX_P HELX_P5  AA5 PRO A 93  ? TRP A 101 ? PRO A 93  TRP A 101 1 ? 9  
HELX_P HELX_P6  AA6 PRO A 102 ? ILE A 106 ? PRO A 102 ILE A 106 5 ? 5  
HELX_P HELX_P7  AA7 PRO A 107 ? GLY A 135 ? PRO A 107 GLY A 135 1 ? 29 
HELX_P HELX_P8  AA8 ASP A 138 ? MET A 150 ? ASP A 138 MET A 150 1 ? 13 
HELX_P HELX_P9  AA9 THR A 152 ? GLY A 162 ? THR A 152 GLY A 162 1 ? 11 
HELX_P HELX_P10 AB1 ASN A 165 ? SER A 178 ? ASN A 165 SER A 178 1 ? 14 
HELX_P HELX_P11 AB2 ARG A 180 ? LYS A 195 ? ARG A 180 LYS A 195 1 ? 16 
HELX_P HELX_P12 AB3 LEU A 196 ? LEU A 199 ? LEU A 196 LEU A 199 5 ? 4  
HELX_P HELX_P13 AB4 VAL A 200 ? ALA A 208 ? VAL A 200 ALA A 208 1 ? 9  
HELX_P HELX_P14 AB5 ARG A 210 ? VAL A 232 ? ARG A 210 VAL A 232 1 ? 23 
HELX_P HELX_P15 AB6 LYS A 246 ? GLY A 251 ? LYS A 246 GLY A 251 1 ? 6  
HELX_P HELX_P16 AB7 SER A 260 ? GLY A 270 ? SER A 260 GLY A 270 1 ? 11 
HELX_P HELX_P17 AB8 GLY A 276 ? ALA A 296 ? GLY A 276 ALA A 296 1 ? 21 
HELX_P HELX_P18 AB9 ASP A 299 ? SER A 315 ? ASP A 299 SER A 315 1 ? 17 
HELX_P HELX_P19 AC1 TRP A 319 ? VAL A 324 ? TRP A 319 VAL A 324 5 ? 6  
HELX_P HELX_P20 AC2 TRP A 325 ? GLY A 336 ? TRP A 325 GLY A 336 1 ? 12 
HELX_P HELX_P21 AC3 LYS A 341 ? GLY A 358 ? LYS A 341 GLY A 358 1 ? 18 
HELX_P HELX_P22 AC4 GLY A 358 ? SER A 364 ? GLY A 358 SER A 364 1 ? 7  
HELX_P HELX_P23 AC5 PRO A 376 ? ALA A 382 ? PRO A 376 ALA A 382 1 ? 7  
HELX_P HELX_P24 AC6 LEU A 384 ? ARG A 403 ? LEU A 384 ARG A 403 1 ? 20 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 78 ? TYR A 79 ? THR A 78 TYR A 79 
AA1 2 LEU A 88 ? PRO A 89 ? LEU A 88 PRO A 89 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    79 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     79 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   LEU 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    88 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    LEU 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     88 
# 
_pdbx_entry_details.entry_id                   9DM5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG A SER 201 ? ? OE2 A GLU 308 ? ? 1.95 
2 1 O  A ALA 175 ? ? OG  A SER 184 ? ? 2.02 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 TRP A 31  ? ? -92.16 52.82 
2 1 HIS A 52  ? ? 71.33  -4.21 
3 1 ALA A 54  ? ? -99.62 30.86 
4 1 GLU A 234 ? ? 69.30  -3.95 
5 1 ASP A 242 ? ? 70.78  -3.67 
6 1 TRP A 323 ? ? -83.36 47.77 
7 1 TRP A 338 ? ? -95.18 58.78 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9DM5 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9DM5 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.46 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               56510 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Mannosyltransferase PimE' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9DM5 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9DM5 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9DM5 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A THR 3   ? A THR 3   
4  1 Y 1 A GLU 4   ? A GLU 4   
5  1 Y 1 A LYS 5   ? A LYS 5   
6  1 Y 1 A THR 6   ? A THR 6   
7  1 Y 1 A GLU 7   ? A GLU 7   
8  1 Y 1 A PRO 8   ? A PRO 8   
9  1 Y 1 A THR 9   ? A THR 9   
10 1 Y 1 A ARG 10  ? A ARG 10  
11 1 Y 1 A ALA 11  ? A ALA 11  
12 1 Y 1 A ASN 12  ? A ASN 12  
13 1 Y 1 A VAL 13  ? A VAL 13  
14 1 Y 1 A GLU 14  ? A GLU 14  
15 1 Y 1 A PRO 15  ? A PRO 15  
16 1 Y 1 A PRO 16  ? A PRO 16  
17 1 Y 1 A MET 17  ? A MET 17  
18 1 Y 1 A PRO 18  ? A PRO 18  
19 1 Y 1 A THR 19  ? A THR 19  
20 1 Y 1 A ARG 20  ? A ARG 20  
21 1 Y 1 A SER 404 ? A SER 404 
22 1 Y 1 A GLY 405 ? A GLY 405 
23 1 Y 1 A HIS 406 ? A HIS 406 
24 1 Y 1 A LEU 407 ? A LEU 407 
25 1 Y 1 A GLY 408 ? A GLY 408 
26 1 Y 1 A ARG 409 ? A ARG 409 
27 1 Y 1 A LEU 410 ? A LEU 410 
28 1 Y 1 A PRO 411 ? A PRO 411 
29 1 Y 1 A TRP 412 ? A TRP 412 
30 1 Y 1 A ARG 413 ? A ARG 413 
31 1 Y 1 A HIS 414 ? A HIS 414 
32 1 Y 1 A VAL 415 ? A VAL 415 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1A8B C4   C N R 1   
A1A8B C5   C N R 2   
A1A8B C6   C N S 3   
A1A8B C7   C N N 4   
A1A8B C8   C N N 5   
A1A8B C10  C N S 6   
A1A8B C13  C N R 7   
A1A8B C15  C N S 8   
A1A8B C17  C N R 9   
A1A8B C20  C N R 10  
A1A8B C21  C N R 11  
A1A8B C22  C N N 12  
A1A8B C24  C N R 13  
A1A8B C26  C N S 14  
A1A8B C28  C N S 15  
A1A8B P1   P N N 16  
A1A8B C1   C N N 17  
A1A8B O1   O N N 18  
A1A8B C2   C N N 19  
A1A8B O2   O N N 20  
A1A8B C3   C N S 21  
A1A8B O3   O N N 22  
A1A8B O4   O N N 23  
A1A8B O5   O N N 24  
A1A8B O6   O N N 25  
A1A8B O7   O N N 26  
A1A8B O8   O N N 27  
A1A8B C9   C N N 28  
A1A8B O9   O N N 29  
A1A8B O10  O N N 30  
A1A8B C11  C N S 31  
A1A8B O11  O N N 32  
A1A8B C12  C N S 33  
A1A8B O12  O N N 34  
A1A8B O13  O N N 35  
A1A8B C14  C N S 36  
A1A8B O14  O N N 37  
A1A8B O15  O N N 38  
A1A8B C16  C N R 39  
A1A8B O16  O N N 40  
A1A8B O17  O N N 41  
A1A8B C18  C N R 42  
A1A8B O18  O N N 43  
A1A8B C19  C N N 44  
A1A8B O19  O N N 45  
A1A8B O20  O N N 46  
A1A8B O21  O N N 47  
A1A8B O22  O N N 48  
A1A8B C23  C N S 49  
A1A8B O23  O N N 50  
A1A8B O24  O N N 51  
A1A8B C25  C N N 52  
A1A8B O25  O N N 53  
A1A8B O26  O N N 54  
A1A8B C27  C N S 55  
A1A8B O27  O N N 56  
A1A8B O28  O N N 57  
A1A8B C29  C N S 58  
A1A8B O29  O N N 59  
A1A8B C30  C N R 60  
A1A8B O30  O N N 61  
A1A8B C31  C N N 62  
A1A8B O31  O N N 63  
A1A8B C32  C N S 64  
A1A8B O32  O N N 65  
A1A8B C33  C N S 66  
A1A8B O33  O N N 67  
A1A8B C34  C N S 68  
A1A8B O34  O N N 69  
A1A8B C35  C N S 70  
A1A8B O35  O N N 71  
A1A8B C36  C N S 72  
A1A8B C37  C N S 73  
A1A8B C38  C N S 74  
A1A8B C39  C N S 75  
A1A8B C40  C N S 76  
A1A8B H1   H N N 77  
A1A8B H2   H N N 78  
A1A8B H3   H N N 79  
A1A8B H4   H N N 80  
A1A8B H5   H N N 81  
A1A8B H6   H N N 82  
A1A8B H7   H N N 83  
A1A8B H8   H N N 84  
A1A8B H9   H N N 85  
A1A8B H10  H N N 86  
A1A8B H11  H N N 87  
A1A8B H12  H N N 88  
A1A8B H13  H N N 89  
A1A8B H14  H N N 90  
A1A8B H15  H N N 91  
A1A8B H16  H N N 92  
A1A8B H17  H N N 93  
A1A8B H20  H N N 94  
A1A8B H21  H N N 95  
A1A8B H22  H N N 96  
A1A8B H23  H N N 97  
A1A8B H24  H N N 98  
A1A8B H25  H N N 99  
A1A8B H27  H N N 100 
A1A8B H28  H N N 101 
A1A8B H29  H N N 102 
A1A8B H30  H N N 103 
A1A8B H31  H N N 104 
A1A8B H32  H N N 105 
A1A8B H33  H N N 106 
A1A8B H34  H N N 107 
A1A8B H35  H N N 108 
A1A8B H36  H N N 109 
A1A8B H37  H N N 110 
A1A8B H38  H N N 111 
A1A8B H39  H N N 112 
A1A8B H40  H N N 113 
A1A8B H41  H N N 114 
A1A8B H42  H N N 115 
A1A8B H43  H N N 116 
A1A8B H44  H N N 117 
A1A8B H45  H N N 118 
A1A8B H46  H N N 119 
A1A8B H47  H N N 120 
A1A8B H48  H N N 121 
A1A8B H49  H N N 122 
A1A8B H50  H N N 123 
A1A8B H51  H N N 124 
A1A8B H52  H N N 125 
A1A8B H53  H N N 126 
A1A8B H54  H N N 127 
A1A8B H55  H N N 128 
A1A8B H56  H N N 129 
A1A8B H57  H N N 130 
A1A8B H58  H N N 131 
A1A8B H59  H N N 132 
A1A8B H60  H N N 133 
A1A8B H61  H N N 134 
A1A8B H62  H N N 135 
A1A8B H63  H N N 136 
A1A8B H64  H N N 137 
A1A8B H65  H N N 138 
A1A8B H66  H N N 139 
A1A8B H67  H N N 140 
A1A8B H68  H N N 141 
A1A8B H69  H N N 142 
A1A8B C41  C N N 143 
A1A8B C42  C N N 144 
A1A8B C43  C N N 145 
A1A8B C44  C N N 146 
A1A8B C45  C N N 147 
A1A8B C46  C N N 148 
A1A8B C47  C N N 149 
A1A8B C48  C N N 150 
A1A8B C49  C N N 151 
A1A8B C50  C N N 152 
A1A8B C51  C N N 153 
A1A8B C52  C N N 154 
A1A8B C53  C N N 155 
A1A8B C54  C N N 156 
A1A8B O38  O N N 157 
A1A8B C56  C N N 158 
A1A8B O36  O N N 159 
A1A8B C58  C N N 160 
A1A8B C57  C N N 161 
A1A8B C59  C N N 162 
A1A8B O37  O N N 163 
A1A8B C55  C N N 164 
A1A8B C60  C N N 165 
A1A8B C61  C N N 166 
A1A8B C62  C N N 167 
A1A8B C63  C N N 168 
A1A8B C64  C N N 169 
A1A8B C65  C N N 170 
A1A8B C66  C N N 171 
A1A8B C67  C N N 172 
A1A8B C68  C N N 173 
A1A8B C69  C N N 174 
A1A8B C70  C N N 175 
A1A8B C71  C N N 176 
A1A8B C72  C N N 177 
A1A8B C73  C N N 178 
A1A8B O39  O N N 179 
A1A8B C74  C N N 180 
A1A8B C75  C N N 181 
A1A8B C76  C N N 182 
A1A8B C77  C N N 183 
A1A8B C78  C N N 184 
A1A8B C79  C N N 185 
A1A8B C80  C N N 186 
A1A8B C81  C N N 187 
A1A8B C82  C N N 188 
A1A8B C83  C N N 189 
A1A8B C84  C N N 190 
A1A8B C85  C N N 191 
A1A8B C86  C N N 192 
A1A8B C87  C N N 193 
A1A8B C88  C N N 194 
A1A8B C89  C N N 195 
A1A8B C90  C N N 196 
A1A8B H18  H N N 197 
A1A8B H19  H N N 198 
A1A8B H26  H N N 199 
A1A8B H70  H N N 200 
A1A8B H71  H N N 201 
A1A8B H72  H N N 202 
A1A8B H73  H N N 203 
A1A8B H74  H N N 204 
A1A8B H75  H N N 205 
A1A8B H76  H N N 206 
A1A8B H77  H N N 207 
A1A8B H78  H N N 208 
A1A8B H79  H N N 209 
A1A8B H80  H N N 210 
A1A8B H81  H N N 211 
A1A8B H82  H N N 212 
A1A8B H83  H N N 213 
A1A8B H84  H N N 214 
A1A8B H85  H N N 215 
A1A8B H86  H N N 216 
A1A8B H87  H N N 217 
A1A8B H88  H N N 218 
A1A8B H89  H N N 219 
A1A8B H90  H N N 220 
A1A8B H91  H N N 221 
A1A8B H92  H N N 222 
A1A8B H93  H N N 223 
A1A8B H94  H N N 224 
A1A8B H95  H N N 225 
A1A8B H96  H N N 226 
A1A8B H97  H N N 227 
A1A8B H98  H N N 228 
A1A8B H99  H N N 229 
A1A8B H100 H N N 230 
A1A8B H101 H N N 231 
A1A8B H102 H N N 232 
A1A8B H103 H N N 233 
A1A8B H104 H N N 234 
A1A8B H105 H N N 235 
ALA   N    N N N 236 
ALA   CA   C N S 237 
ALA   C    C N N 238 
ALA   O    O N N 239 
ALA   CB   C N N 240 
ALA   OXT  O N N 241 
ALA   H    H N N 242 
ALA   H2   H N N 243 
ALA   HA   H N N 244 
ALA   HB1  H N N 245 
ALA   HB2  H N N 246 
ALA   HB3  H N N 247 
ALA   HXT  H N N 248 
ARG   N    N N N 249 
ARG   CA   C N S 250 
ARG   C    C N N 251 
ARG   O    O N N 252 
ARG   CB   C N N 253 
ARG   CG   C N N 254 
ARG   CD   C N N 255 
ARG   NE   N N N 256 
ARG   CZ   C N N 257 
ARG   NH1  N N N 258 
ARG   NH2  N N N 259 
ARG   OXT  O N N 260 
ARG   H    H N N 261 
ARG   H2   H N N 262 
ARG   HA   H N N 263 
ARG   HB2  H N N 264 
ARG   HB3  H N N 265 
ARG   HG2  H N N 266 
ARG   HG3  H N N 267 
ARG   HD2  H N N 268 
ARG   HD3  H N N 269 
ARG   HE   H N N 270 
ARG   HH11 H N N 271 
ARG   HH12 H N N 272 
ARG   HH21 H N N 273 
ARG   HH22 H N N 274 
ARG   HXT  H N N 275 
ASN   N    N N N 276 
ASN   CA   C N S 277 
ASN   C    C N N 278 
ASN   O    O N N 279 
ASN   CB   C N N 280 
ASN   CG   C N N 281 
ASN   OD1  O N N 282 
ASN   ND2  N N N 283 
ASN   OXT  O N N 284 
ASN   H    H N N 285 
ASN   H2   H N N 286 
ASN   HA   H N N 287 
ASN   HB2  H N N 288 
ASN   HB3  H N N 289 
ASN   HD21 H N N 290 
ASN   HD22 H N N 291 
ASN   HXT  H N N 292 
ASP   N    N N N 293 
ASP   CA   C N S 294 
ASP   C    C N N 295 
ASP   O    O N N 296 
ASP   CB   C N N 297 
ASP   CG   C N N 298 
ASP   OD1  O N N 299 
ASP   OD2  O N N 300 
ASP   OXT  O N N 301 
ASP   H    H N N 302 
ASP   H2   H N N 303 
ASP   HA   H N N 304 
ASP   HB2  H N N 305 
ASP   HB3  H N N 306 
ASP   HD2  H N N 307 
ASP   HXT  H N N 308 
CYS   N    N N N 309 
CYS   CA   C N R 310 
CYS   C    C N N 311 
CYS   O    O N N 312 
CYS   CB   C N N 313 
CYS   SG   S N N 314 
CYS   OXT  O N N 315 
CYS   H    H N N 316 
CYS   H2   H N N 317 
CYS   HA   H N N 318 
CYS   HB2  H N N 319 
CYS   HB3  H N N 320 
CYS   HG   H N N 321 
CYS   HXT  H N N 322 
DSL   C06  C N N 323 
DSL   C07  C N N 324 
DSL   C08  C N N 325 
DSL   C09  C N N 326 
DSL   C10  C N N 327 
DSL   C11  C N N 328 
DSL   C12  C N N 329 
DSL   C13  C N N 330 
DSL   C14  C N N 331 
DSL   C15  C N N 332 
DSL   C16  C N N 333 
DSL   C17  C N N 334 
DSL   C18  C N N 335 
DSL   C19  C N N 336 
DSL   C20  C N N 337 
DSL   C21  C N N 338 
DSL   C22  C N N 339 
DSL   C23  C N N 340 
DSL   C24  C N N 341 
DSL   C25  C N N 342 
DSL   C26  C N N 343 
DSL   C27  C N N 344 
DSL   C28  C N N 345 
DSL   C29  C N N 346 
DSL   C30  C N N 347 
DSL   C31  C N N 348 
DSL   C32  C N N 349 
DSL   C33  C N N 350 
DSL   C34  C N N 351 
DSL   C35  C N N 352 
DSL   C36  C N N 353 
DSL   C37  C N N 354 
DSL   C38  C N N 355 
DSL   C39  C N N 356 
DSL   C40  C N N 357 
DSL   C41  C N N 358 
DSL   C42  C N N 359 
DSL   C43  C N N 360 
DSL   C44  C N N 361 
DSL   C45  C N N 362 
DSL   C46  C N N 363 
DSL   C47  C N N 364 
DSL   C48  C N N 365 
DSL   C49  C N N 366 
DSL   C50  C N N 367 
DSL   C51  C N N 368 
DSL   C52  C N N 369 
DSL   C53  C N N 370 
DSL   C54  C N N 371 
DSL   C55  C N N 372 
DSL   O56  O N N 373 
DSL   P57  P N N 374 
DSL   O58  O N N 375 
DSL   O59  O N N 376 
DSL   O60  O N N 377 
DSL   H061 H N N 378 
DSL   H062 H N N 379 
DSL   H063 H N N 380 
DSL   H081 H N N 381 
DSL   H082 H N N 382 
DSL   H083 H N N 383 
DSL   H09  H N N 384 
DSL   H101 H N N 385 
DSL   H102 H N N 386 
DSL   H111 H N N 387 
DSL   H112 H N N 388 
DSL   H131 H N N 389 
DSL   H132 H N N 390 
DSL   H133 H N N 391 
DSL   H14  H N N 392 
DSL   H151 H N N 393 
DSL   H152 H N N 394 
DSL   H161 H N N 395 
DSL   H162 H N N 396 
DSL   H181 H N N 397 
DSL   H182 H N N 398 
DSL   H183 H N N 399 
DSL   H19  H N N 400 
DSL   H201 H N N 401 
DSL   H202 H N N 402 
DSL   H211 H N N 403 
DSL   H212 H N N 404 
DSL   H231 H N N 405 
DSL   H232 H N N 406 
DSL   H233 H N N 407 
DSL   H24  H N N 408 
DSL   H251 H N N 409 
DSL   H252 H N N 410 
DSL   H261 H N N 411 
DSL   H262 H N N 412 
DSL   H281 H N N 413 
DSL   H282 H N N 414 
DSL   H283 H N N 415 
DSL   H29  H N N 416 
DSL   H301 H N N 417 
DSL   H302 H N N 418 
DSL   H311 H N N 419 
DSL   H312 H N N 420 
DSL   H331 H N N 421 
DSL   H332 H N N 422 
DSL   H333 H N N 423 
DSL   H34  H N N 424 
DSL   H351 H N N 425 
DSL   H352 H N N 426 
DSL   H361 H N N 427 
DSL   H362 H N N 428 
DSL   H381 H N N 429 
DSL   H382 H N N 430 
DSL   H383 H N N 431 
DSL   H39  H N N 432 
DSL   H401 H N N 433 
DSL   H402 H N N 434 
DSL   H411 H N N 435 
DSL   H412 H N N 436 
DSL   H431 H N N 437 
DSL   H432 H N N 438 
DSL   H433 H N N 439 
DSL   H44  H N N 440 
DSL   H451 H N N 441 
DSL   H452 H N N 442 
DSL   H461 H N N 443 
DSL   H462 H N N 444 
DSL   H481 H N N 445 
DSL   H482 H N N 446 
DSL   H483 H N N 447 
DSL   H49  H N N 448 
DSL   H501 H N N 449 
DSL   H502 H N N 450 
DSL   H511 H N N 451 
DSL   H512 H N N 452 
DSL   H531 H N N 453 
DSL   H532 H N N 454 
DSL   H533 H N N 455 
DSL   H54  H N N 456 
DSL   H551 H N N 457 
DSL   H552 H N N 458 
DSL   H60  H N N 459 
DSL   H59  H N N 460 
GLN   N    N N N 461 
GLN   CA   C N S 462 
GLN   C    C N N 463 
GLN   O    O N N 464 
GLN   CB   C N N 465 
GLN   CG   C N N 466 
GLN   CD   C N N 467 
GLN   OE1  O N N 468 
GLN   NE2  N N N 469 
GLN   OXT  O N N 470 
GLN   H    H N N 471 
GLN   H2   H N N 472 
GLN   HA   H N N 473 
GLN   HB2  H N N 474 
GLN   HB3  H N N 475 
GLN   HG2  H N N 476 
GLN   HG3  H N N 477 
GLN   HE21 H N N 478 
GLN   HE22 H N N 479 
GLN   HXT  H N N 480 
GLU   N    N N N 481 
GLU   CA   C N S 482 
GLU   C    C N N 483 
GLU   O    O N N 484 
GLU   CB   C N N 485 
GLU   CG   C N N 486 
GLU   CD   C N N 487 
GLU   OE1  O N N 488 
GLU   OE2  O N N 489 
GLU   OXT  O N N 490 
GLU   H    H N N 491 
GLU   H2   H N N 492 
GLU   HA   H N N 493 
GLU   HB2  H N N 494 
GLU   HB3  H N N 495 
GLU   HG2  H N N 496 
GLU   HG3  H N N 497 
GLU   HE2  H N N 498 
GLU   HXT  H N N 499 
GLY   N    N N N 500 
GLY   CA   C N N 501 
GLY   C    C N N 502 
GLY   O    O N N 503 
GLY   OXT  O N N 504 
GLY   H    H N N 505 
GLY   H2   H N N 506 
GLY   HA2  H N N 507 
GLY   HA3  H N N 508 
GLY   HXT  H N N 509 
HIS   N    N N N 510 
HIS   CA   C N S 511 
HIS   C    C N N 512 
HIS   O    O N N 513 
HIS   CB   C N N 514 
HIS   CG   C Y N 515 
HIS   ND1  N Y N 516 
HIS   CD2  C Y N 517 
HIS   CE1  C Y N 518 
HIS   NE2  N Y N 519 
HIS   OXT  O N N 520 
HIS   H    H N N 521 
HIS   H2   H N N 522 
HIS   HA   H N N 523 
HIS   HB2  H N N 524 
HIS   HB3  H N N 525 
HIS   HD1  H N N 526 
HIS   HD2  H N N 527 
HIS   HE1  H N N 528 
HIS   HE2  H N N 529 
HIS   HXT  H N N 530 
ILE   N    N N N 531 
ILE   CA   C N S 532 
ILE   C    C N N 533 
ILE   O    O N N 534 
ILE   CB   C N S 535 
ILE   CG1  C N N 536 
ILE   CG2  C N N 537 
ILE   CD1  C N N 538 
ILE   OXT  O N N 539 
ILE   H    H N N 540 
ILE   H2   H N N 541 
ILE   HA   H N N 542 
ILE   HB   H N N 543 
ILE   HG12 H N N 544 
ILE   HG13 H N N 545 
ILE   HG21 H N N 546 
ILE   HG22 H N N 547 
ILE   HG23 H N N 548 
ILE   HD11 H N N 549 
ILE   HD12 H N N 550 
ILE   HD13 H N N 551 
ILE   HXT  H N N 552 
LEU   N    N N N 553 
LEU   CA   C N S 554 
LEU   C    C N N 555 
LEU   O    O N N 556 
LEU   CB   C N N 557 
LEU   CG   C N N 558 
LEU   CD1  C N N 559 
LEU   CD2  C N N 560 
LEU   OXT  O N N 561 
LEU   H    H N N 562 
LEU   H2   H N N 563 
LEU   HA   H N N 564 
LEU   HB2  H N N 565 
LEU   HB3  H N N 566 
LEU   HG   H N N 567 
LEU   HD11 H N N 568 
LEU   HD12 H N N 569 
LEU   HD13 H N N 570 
LEU   HD21 H N N 571 
LEU   HD22 H N N 572 
LEU   HD23 H N N 573 
LEU   HXT  H N N 574 
LYS   N    N N N 575 
LYS   CA   C N S 576 
LYS   C    C N N 577 
LYS   O    O N N 578 
LYS   CB   C N N 579 
LYS   CG   C N N 580 
LYS   CD   C N N 581 
LYS   CE   C N N 582 
LYS   NZ   N N N 583 
LYS   OXT  O N N 584 
LYS   H    H N N 585 
LYS   H2   H N N 586 
LYS   HA   H N N 587 
LYS   HB2  H N N 588 
LYS   HB3  H N N 589 
LYS   HG2  H N N 590 
LYS   HG3  H N N 591 
LYS   HD2  H N N 592 
LYS   HD3  H N N 593 
LYS   HE2  H N N 594 
LYS   HE3  H N N 595 
LYS   HZ1  H N N 596 
LYS   HZ2  H N N 597 
LYS   HZ3  H N N 598 
LYS   HXT  H N N 599 
MET   N    N N N 600 
MET   CA   C N S 601 
MET   C    C N N 602 
MET   O    O N N 603 
MET   CB   C N N 604 
MET   CG   C N N 605 
MET   SD   S N N 606 
MET   CE   C N N 607 
MET   OXT  O N N 608 
MET   H    H N N 609 
MET   H2   H N N 610 
MET   HA   H N N 611 
MET   HB2  H N N 612 
MET   HB3  H N N 613 
MET   HG2  H N N 614 
MET   HG3  H N N 615 
MET   HE1  H N N 616 
MET   HE2  H N N 617 
MET   HE3  H N N 618 
MET   HXT  H N N 619 
PHE   N    N N N 620 
PHE   CA   C N S 621 
PHE   C    C N N 622 
PHE   O    O N N 623 
PHE   CB   C N N 624 
PHE   CG   C Y N 625 
PHE   CD1  C Y N 626 
PHE   CD2  C Y N 627 
PHE   CE1  C Y N 628 
PHE   CE2  C Y N 629 
PHE   CZ   C Y N 630 
PHE   OXT  O N N 631 
PHE   H    H N N 632 
PHE   H2   H N N 633 
PHE   HA   H N N 634 
PHE   HB2  H N N 635 
PHE   HB3  H N N 636 
PHE   HD1  H N N 637 
PHE   HD2  H N N 638 
PHE   HE1  H N N 639 
PHE   HE2  H N N 640 
PHE   HZ   H N N 641 
PHE   HXT  H N N 642 
PRO   N    N N N 643 
PRO   CA   C N S 644 
PRO   C    C N N 645 
PRO   O    O N N 646 
PRO   CB   C N N 647 
PRO   CG   C N N 648 
PRO   CD   C N N 649 
PRO   OXT  O N N 650 
PRO   H    H N N 651 
PRO   HA   H N N 652 
PRO   HB2  H N N 653 
PRO   HB3  H N N 654 
PRO   HG2  H N N 655 
PRO   HG3  H N N 656 
PRO   HD2  H N N 657 
PRO   HD3  H N N 658 
PRO   HXT  H N N 659 
SER   N    N N N 660 
SER   CA   C N S 661 
SER   C    C N N 662 
SER   O    O N N 663 
SER   CB   C N N 664 
SER   OG   O N N 665 
SER   OXT  O N N 666 
SER   H    H N N 667 
SER   H2   H N N 668 
SER   HA   H N N 669 
SER   HB2  H N N 670 
SER   HB3  H N N 671 
SER   HG   H N N 672 
SER   HXT  H N N 673 
THR   N    N N N 674 
THR   CA   C N S 675 
THR   C    C N N 676 
THR   O    O N N 677 
THR   CB   C N R 678 
THR   OG1  O N N 679 
THR   CG2  C N N 680 
THR   OXT  O N N 681 
THR   H    H N N 682 
THR   H2   H N N 683 
THR   HA   H N N 684 
THR   HB   H N N 685 
THR   HG1  H N N 686 
THR   HG21 H N N 687 
THR   HG22 H N N 688 
THR   HG23 H N N 689 
THR   HXT  H N N 690 
TRP   N    N N N 691 
TRP   CA   C N S 692 
TRP   C    C N N 693 
TRP   O    O N N 694 
TRP   CB   C N N 695 
TRP   CG   C Y N 696 
TRP   CD1  C Y N 697 
TRP   CD2  C Y N 698 
TRP   NE1  N Y N 699 
TRP   CE2  C Y N 700 
TRP   CE3  C Y N 701 
TRP   CZ2  C Y N 702 
TRP   CZ3  C Y N 703 
TRP   CH2  C Y N 704 
TRP   OXT  O N N 705 
TRP   H    H N N 706 
TRP   H2   H N N 707 
TRP   HA   H N N 708 
TRP   HB2  H N N 709 
TRP   HB3  H N N 710 
TRP   HD1  H N N 711 
TRP   HE1  H N N 712 
TRP   HE3  H N N 713 
TRP   HZ2  H N N 714 
TRP   HZ3  H N N 715 
TRP   HH2  H N N 716 
TRP   HXT  H N N 717 
TYR   N    N N N 718 
TYR   CA   C N S 719 
TYR   C    C N N 720 
TYR   O    O N N 721 
TYR   CB   C N N 722 
TYR   CG   C Y N 723 
TYR   CD1  C Y N 724 
TYR   CD2  C Y N 725 
TYR   CE1  C Y N 726 
TYR   CE2  C Y N 727 
TYR   CZ   C Y N 728 
TYR   OH   O N N 729 
TYR   OXT  O N N 730 
TYR   H    H N N 731 
TYR   H2   H N N 732 
TYR   HA   H N N 733 
TYR   HB2  H N N 734 
TYR   HB3  H N N 735 
TYR   HD1  H N N 736 
TYR   HD2  H N N 737 
TYR   HE1  H N N 738 
TYR   HE2  H N N 739 
TYR   HH   H N N 740 
TYR   HXT  H N N 741 
VAL   N    N N N 742 
VAL   CA   C N S 743 
VAL   C    C N N 744 
VAL   O    O N N 745 
VAL   CB   C N N 746 
VAL   CG1  C N N 747 
VAL   CG2  C N N 748 
VAL   OXT  O N N 749 
VAL   H    H N N 750 
VAL   H2   H N N 751 
VAL   HA   H N N 752 
VAL   HB   H N N 753 
VAL   HG11 H N N 754 
VAL   HG12 H N N 755 
VAL   HG13 H N N 756 
VAL   HG21 H N N 757 
VAL   HG22 H N N 758 
VAL   HG23 H N N 759 
VAL   HXT  H N N 760 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1A8B O3  P1   doub N N 1   
A1A8B O35 C40  sing N N 2   
A1A8B C2  O1   sing N N 3   
A1A8B C2  C1   sing N N 4   
A1A8B O2  P1   sing N N 5   
A1A8B P1  O1   sing N N 6   
A1A8B P1  O4   sing N N 7   
A1A8B C40 C39  sing N N 8   
A1A8B C40 C17  sing N N 9   
A1A8B O34 C39  sing N N 10  
A1A8B C39 C38  sing N N 11  
A1A8B O31 C36  sing N N 12  
A1A8B O14 C15  sing N N 13  
A1A8B O32 C37  sing N N 14  
A1A8B O4  C3   sing N N 15  
A1A8B C17 O16  sing N N 16  
A1A8B C17 O15  sing N N 17  
A1A8B C16 C15  sing N N 18  
A1A8B C16 C3   sing N N 19  
A1A8B C16 O15  sing N N 20  
A1A8B C37 C36  sing N N 21  
A1A8B C37 C20  sing N N 22  
A1A8B C36 C35  sing N N 23  
A1A8B O21 C25  sing N N 24  
A1A8B C15 C14  sing N N 25  
A1A8B O8  C8   doub N N 26  
A1A8B C3  C4   sing N N 27  
A1A8B O16 C18  sing N N 28  
A1A8B C38 O33  sing N N 29  
A1A8B C38 C18  sing N N 30  
A1A8B C7  O7   sing N N 31  
A1A8B C7  C6   sing N N 32  
A1A8B O17 C20  sing N N 33  
A1A8B O17 C19  sing N N 34  
A1A8B C20 O18  sing N N 35  
A1A8B C8  O7   sing N N 36  
A1A8B C8  C9   sing N N 37  
A1A8B C25 C24  sing N N 38  
A1A8B C35 O30  sing N N 39  
A1A8B C35 C21  sing N N 40  
A1A8B C18 C19  sing N N 41  
A1A8B O6  C6   sing N N 42  
A1A8B O6  C5   sing N N 43  
A1A8B C14 O13  sing N N 44  
A1A8B C14 C13  sing N N 45  
A1A8B C22 C21  sing N N 46  
A1A8B C22 O19  sing N N 47  
A1A8B C6  C10  sing N N 48  
A1A8B C4  O5   sing N N 49  
A1A8B C4  C13  sing N N 50  
A1A8B O5  C5   sing N N 51  
A1A8B O18 C21  sing N N 52  
A1A8B C24 O20  sing N N 53  
A1A8B C24 C26  sing N N 54  
A1A8B C13 O12  sing N N 55  
A1A8B C5  C12  sing N N 56  
A1A8B O22 C26  sing N N 57  
A1A8B O20 C23  sing N N 58  
A1A8B O19 C23  sing N N 59  
A1A8B C12 C11  sing N N 60  
A1A8B C12 O11  sing N N 61  
A1A8B C26 C27  sing N N 62  
A1A8B C10 C11  sing N N 63  
A1A8B C10 O9   sing N N 64  
A1A8B C11 O10  sing N N 65  
A1A8B C23 C28  sing N N 66  
A1A8B C27 C28  sing N N 67  
A1A8B C27 O23  sing N N 68  
A1A8B C28 O24  sing N N 69  
A1A8B O24 C29  sing N N 70  
A1A8B O29 C34  sing N N 71  
A1A8B C29 O25  sing N N 72  
A1A8B C29 C34  sing N N 73  
A1A8B O25 C30  sing N N 74  
A1A8B C34 C33  sing N N 75  
A1A8B O28 C33  sing N N 76  
A1A8B C31 C30  sing N N 77  
A1A8B C31 O26  sing N N 78  
A1A8B C30 C32  sing N N 79  
A1A8B C33 C32  sing N N 80  
A1A8B C32 O27  sing N N 81  
A1A8B C4  H1   sing N N 82  
A1A8B C5  H2   sing N N 83  
A1A8B C6  H3   sing N N 84  
A1A8B C7  H4   sing N N 85  
A1A8B C7  H5   sing N N 86  
A1A8B C10 H6   sing N N 87  
A1A8B C13 H7   sing N N 88  
A1A8B C15 H8   sing N N 89  
A1A8B C17 H9   sing N N 90  
A1A8B C20 H10  sing N N 91  
A1A8B C21 H11  sing N N 92  
A1A8B C22 H12  sing N N 93  
A1A8B C22 H13  sing N N 94  
A1A8B C24 H14  sing N N 95  
A1A8B C26 H15  sing N N 96  
A1A8B C28 H16  sing N N 97  
A1A8B C1  H17  sing N N 98  
A1A8B C2  H20  sing N N 99  
A1A8B C2  H21  sing N N 100 
A1A8B O2  H22  sing N N 101 
A1A8B C3  H23  sing N N 102 
A1A8B C9  H24  sing N N 103 
A1A8B C9  H25  sing N N 104 
A1A8B O9  H27  sing N N 105 
A1A8B O10 H28  sing N N 106 
A1A8B C11 H29  sing N N 107 
A1A8B O11 H30  sing N N 108 
A1A8B C12 H31  sing N N 109 
A1A8B O12 H32  sing N N 110 
A1A8B O13 H33  sing N N 111 
A1A8B C14 H34  sing N N 112 
A1A8B O14 H35  sing N N 113 
A1A8B C16 H36  sing N N 114 
A1A8B C18 H37  sing N N 115 
A1A8B C19 H38  sing N N 116 
A1A8B C19 H39  sing N N 117 
A1A8B O21 H40  sing N N 118 
A1A8B O22 H41  sing N N 119 
A1A8B C23 H42  sing N N 120 
A1A8B O23 H43  sing N N 121 
A1A8B C25 H44  sing N N 122 
A1A8B C25 H45  sing N N 123 
A1A8B O26 H46  sing N N 124 
A1A8B C27 H47  sing N N 125 
A1A8B O27 H48  sing N N 126 
A1A8B O28 H49  sing N N 127 
A1A8B C29 H50  sing N N 128 
A1A8B O29 H51  sing N N 129 
A1A8B C30 H52  sing N N 130 
A1A8B O30 H53  sing N N 131 
A1A8B C31 H54  sing N N 132 
A1A8B C31 H55  sing N N 133 
A1A8B O31 H56  sing N N 134 
A1A8B C32 H57  sing N N 135 
A1A8B O32 H58  sing N N 136 
A1A8B C33 H59  sing N N 137 
A1A8B O33 H60  sing N N 138 
A1A8B C34 H61  sing N N 139 
A1A8B O34 H62  sing N N 140 
A1A8B C35 H63  sing N N 141 
A1A8B O35 H64  sing N N 142 
A1A8B C36 H65  sing N N 143 
A1A8B C37 H66  sing N N 144 
A1A8B C38 H67  sing N N 145 
A1A8B C39 H68  sing N N 146 
A1A8B C40 H69  sing N N 147 
A1A8B C9  C41  sing N N 148 
A1A8B C41 C42  sing N N 149 
A1A8B C42 C43  sing N N 150 
A1A8B C43 C44  sing N N 151 
A1A8B C44 C45  sing N N 152 
A1A8B C45 C46  sing N N 153 
A1A8B C46 C47  sing N N 154 
A1A8B C47 C48  sing N N 155 
A1A8B C48 C49  sing N N 156 
A1A8B C49 C50  sing N N 157 
A1A8B C50 C51  sing N N 158 
A1A8B C51 C52  sing N N 159 
A1A8B C52 C53  sing N N 160 
A1A8B C53 C54  sing N N 161 
A1A8B C1  O38  sing N N 162 
A1A8B C1  C56  sing N N 163 
A1A8B C56 O36  sing N N 164 
A1A8B O36 C58  sing N N 165 
A1A8B C58 C57  sing N N 166 
A1A8B C57 C59  sing N N 167 
A1A8B C58 O37  doub N N 168 
A1A8B C59 C55  sing N N 169 
A1A8B C55 C60  sing N N 170 
A1A8B C60 C61  sing N N 171 
A1A8B C61 C62  sing N N 172 
A1A8B C62 C63  sing N N 173 
A1A8B C63 C64  sing N N 174 
A1A8B C64 C65  sing N N 175 
A1A8B C65 C66  sing N N 176 
A1A8B C66 C67  sing N N 177 
A1A8B C67 C68  sing N N 178 
A1A8B C68 C69  sing N N 179 
A1A8B C69 C70  sing N N 180 
A1A8B C70 C71  sing N N 181 
A1A8B O38 C72  sing N N 182 
A1A8B C72 C73  sing N N 183 
A1A8B C72 O39  doub N N 184 
A1A8B C73 C74  sing N N 185 
A1A8B C74 C75  sing N N 186 
A1A8B C75 C76  sing N N 187 
A1A8B C76 C77  sing N N 188 
A1A8B C77 C78  sing N N 189 
A1A8B C78 C79  sing N N 190 
A1A8B C79 C80  sing N N 191 
A1A8B C80 C81  sing N N 192 
A1A8B C81 C82  sing N N 193 
A1A8B C82 C83  sing N N 194 
A1A8B C83 C84  sing N N 195 
A1A8B C84 C85  sing N N 196 
A1A8B C85 C86  sing N N 197 
A1A8B C86 C87  sing N N 198 
A1A8B C87 C88  sing N N 199 
A1A8B C88 C89  sing N N 200 
A1A8B C81 C90  sing N N 201 
A1A8B C41 H18  sing N N 202 
A1A8B C41 H19  sing N N 203 
A1A8B C42 H26  sing N N 204 
A1A8B C42 H70  sing N N 205 
A1A8B C43 H71  sing N N 206 
A1A8B C43 H72  sing N N 207 
A1A8B C44 H73  sing N N 208 
A1A8B C44 H74  sing N N 209 
A1A8B C45 H75  sing N N 210 
A1A8B C45 H76  sing N N 211 
A1A8B C46 H77  sing N N 212 
A1A8B C46 H78  sing N N 213 
A1A8B C47 H79  sing N N 214 
A1A8B C47 H80  sing N N 215 
A1A8B C48 H81  sing N N 216 
A1A8B C48 H82  sing N N 217 
A1A8B C49 H83  sing N N 218 
A1A8B C49 H84  sing N N 219 
A1A8B C50 H85  sing N N 220 
A1A8B C50 H86  sing N N 221 
A1A8B C51 H87  sing N N 222 
A1A8B C51 H88  sing N N 223 
A1A8B C52 H89  sing N N 224 
A1A8B C52 H90  sing N N 225 
A1A8B C53 H91  sing N N 226 
A1A8B C53 H92  sing N N 227 
A1A8B C54 H93  sing N N 228 
A1A8B C54 H94  sing N N 229 
A1A8B C54 H95  sing N N 230 
A1A8B C56 H96  sing N N 231 
A1A8B C56 H97  sing N N 232 
A1A8B C57 H98  sing N N 233 
A1A8B C57 H99  sing N N 234 
A1A8B C59 H100 sing N N 235 
A1A8B C59 H101 sing N N 236 
A1A8B C55 H102 sing N N 237 
A1A8B C55 H103 sing N N 238 
A1A8B C60 H104 sing N N 239 
A1A8B C60 H105 sing N N 240 
ALA   N   CA   sing N N 241 
ALA   N   H    sing N N 242 
ALA   N   H2   sing N N 243 
ALA   CA  C    sing N N 244 
ALA   CA  CB   sing N N 245 
ALA   CA  HA   sing N N 246 
ALA   C   O    doub N N 247 
ALA   C   OXT  sing N N 248 
ALA   CB  HB1  sing N N 249 
ALA   CB  HB2  sing N N 250 
ALA   CB  HB3  sing N N 251 
ALA   OXT HXT  sing N N 252 
ARG   N   CA   sing N N 253 
ARG   N   H    sing N N 254 
ARG   N   H2   sing N N 255 
ARG   CA  C    sing N N 256 
ARG   CA  CB   sing N N 257 
ARG   CA  HA   sing N N 258 
ARG   C   O    doub N N 259 
ARG   C   OXT  sing N N 260 
ARG   CB  CG   sing N N 261 
ARG   CB  HB2  sing N N 262 
ARG   CB  HB3  sing N N 263 
ARG   CG  CD   sing N N 264 
ARG   CG  HG2  sing N N 265 
ARG   CG  HG3  sing N N 266 
ARG   CD  NE   sing N N 267 
ARG   CD  HD2  sing N N 268 
ARG   CD  HD3  sing N N 269 
ARG   NE  CZ   sing N N 270 
ARG   NE  HE   sing N N 271 
ARG   CZ  NH1  sing N N 272 
ARG   CZ  NH2  doub N N 273 
ARG   NH1 HH11 sing N N 274 
ARG   NH1 HH12 sing N N 275 
ARG   NH2 HH21 sing N N 276 
ARG   NH2 HH22 sing N N 277 
ARG   OXT HXT  sing N N 278 
ASN   N   CA   sing N N 279 
ASN   N   H    sing N N 280 
ASN   N   H2   sing N N 281 
ASN   CA  C    sing N N 282 
ASN   CA  CB   sing N N 283 
ASN   CA  HA   sing N N 284 
ASN   C   O    doub N N 285 
ASN   C   OXT  sing N N 286 
ASN   CB  CG   sing N N 287 
ASN   CB  HB2  sing N N 288 
ASN   CB  HB3  sing N N 289 
ASN   CG  OD1  doub N N 290 
ASN   CG  ND2  sing N N 291 
ASN   ND2 HD21 sing N N 292 
ASN   ND2 HD22 sing N N 293 
ASN   OXT HXT  sing N N 294 
ASP   N   CA   sing N N 295 
ASP   N   H    sing N N 296 
ASP   N   H2   sing N N 297 
ASP   CA  C    sing N N 298 
ASP   CA  CB   sing N N 299 
ASP   CA  HA   sing N N 300 
ASP   C   O    doub N N 301 
ASP   C   OXT  sing N N 302 
ASP   CB  CG   sing N N 303 
ASP   CB  HB2  sing N N 304 
ASP   CB  HB3  sing N N 305 
ASP   CG  OD1  doub N N 306 
ASP   CG  OD2  sing N N 307 
ASP   OD2 HD2  sing N N 308 
ASP   OXT HXT  sing N N 309 
CYS   N   CA   sing N N 310 
CYS   N   H    sing N N 311 
CYS   N   H2   sing N N 312 
CYS   CA  C    sing N N 313 
CYS   CA  CB   sing N N 314 
CYS   CA  HA   sing N N 315 
CYS   C   O    doub N N 316 
CYS   C   OXT  sing N N 317 
CYS   CB  SG   sing N N 318 
CYS   CB  HB2  sing N N 319 
CYS   CB  HB3  sing N N 320 
CYS   SG  HG   sing N N 321 
CYS   OXT HXT  sing N N 322 
DSL   C06 C07  sing N N 323 
DSL   C07 C08  sing N N 324 
DSL   C07 C09  doub N N 325 
DSL   C09 C10  sing N N 326 
DSL   C10 C11  sing N N 327 
DSL   C11 C12  sing N N 328 
DSL   C12 C13  sing N N 329 
DSL   C12 C14  doub N N 330 
DSL   C14 C15  sing N N 331 
DSL   C15 C16  sing N N 332 
DSL   C16 C17  sing N N 333 
DSL   C17 C18  sing N N 334 
DSL   C17 C19  doub N N 335 
DSL   C19 C20  sing N N 336 
DSL   C20 C21  sing N N 337 
DSL   C21 C22  sing N N 338 
DSL   C22 C23  sing N N 339 
DSL   C22 C24  doub N N 340 
DSL   C24 C25  sing N E 341 
DSL   C25 C26  sing N N 342 
DSL   C26 C27  sing N N 343 
DSL   C27 C28  sing N N 344 
DSL   C27 C29  doub N N 345 
DSL   C29 C30  sing N N 346 
DSL   C30 C31  sing N N 347 
DSL   C31 C32  sing N N 348 
DSL   C32 C33  sing N N 349 
DSL   C32 C34  doub N N 350 
DSL   C34 C35  sing N N 351 
DSL   C35 C36  sing N N 352 
DSL   C36 C37  sing N N 353 
DSL   C37 C38  sing N Z 354 
DSL   C37 C39  doub N N 355 
DSL   C39 C40  sing N N 356 
DSL   C40 C41  sing N N 357 
DSL   C41 C42  sing N N 358 
DSL   C42 C43  sing N N 359 
DSL   C42 C44  doub N N 360 
DSL   C44 C45  sing N N 361 
DSL   C45 C46  sing N N 362 
DSL   C46 C47  sing N N 363 
DSL   C47 C48  sing N N 364 
DSL   C47 C49  doub N N 365 
DSL   C49 C50  sing N N 366 
DSL   C50 C51  sing N Z 367 
DSL   C51 C52  sing N N 368 
DSL   C52 C53  sing N N 369 
DSL   C52 C54  doub N N 370 
DSL   C54 C55  sing N N 371 
DSL   C55 O56  sing N N 372 
DSL   O56 P57  sing N N 373 
DSL   P57 O58  doub N N 374 
DSL   P57 O59  sing N N 375 
DSL   P57 O60  sing N N 376 
DSL   C06 H061 sing N N 377 
DSL   C06 H062 sing N N 378 
DSL   C06 H063 sing N N 379 
DSL   C08 H081 sing N Z 380 
DSL   C08 H082 sing N N 381 
DSL   C08 H083 sing N N 382 
DSL   C09 H09  sing N N 383 
DSL   C10 H101 sing N N 384 
DSL   C10 H102 sing N N 385 
DSL   C11 H111 sing N N 386 
DSL   C11 H112 sing N N 387 
DSL   C13 H131 sing N N 388 
DSL   C13 H132 sing N N 389 
DSL   C13 H133 sing N N 390 
DSL   C14 H14  sing N N 391 
DSL   C15 H151 sing N N 392 
DSL   C15 H152 sing N Z 393 
DSL   C16 H161 sing N N 394 
DSL   C16 H162 sing N N 395 
DSL   C18 H181 sing N N 396 
DSL   C18 H182 sing N N 397 
DSL   C18 H183 sing N N 398 
DSL   C19 H19  sing N N 399 
DSL   C20 H201 sing N N 400 
DSL   C20 H202 sing N N 401 
DSL   C21 H211 sing N N 402 
DSL   C21 H212 sing N N 403 
DSL   C23 H231 sing N N 404 
DSL   C23 H232 sing N N 405 
DSL   C23 H233 sing N Z 406 
DSL   C24 H24  sing N N 407 
DSL   C25 H251 sing N N 408 
DSL   C25 H252 sing N N 409 
DSL   C26 H261 sing N N 410 
DSL   C26 H262 sing N N 411 
DSL   C28 H281 sing N N 412 
DSL   C28 H282 sing N N 413 
DSL   C28 H283 sing N N 414 
DSL   C29 H29  sing N N 415 
DSL   C30 H301 sing N N 416 
DSL   C30 H302 sing N N 417 
DSL   C31 H311 sing N N 418 
DSL   C31 H312 sing N Z 419 
DSL   C33 H331 sing N N 420 
DSL   C33 H332 sing N N 421 
DSL   C33 H333 sing N N 422 
DSL   C34 H34  sing N N 423 
DSL   C35 H351 sing N N 424 
DSL   C35 H352 sing N N 425 
DSL   C36 H361 sing N N 426 
DSL   C36 H362 sing N N 427 
DSL   C38 H381 sing N N 428 
DSL   C38 H382 sing N N 429 
DSL   C38 H383 sing N N 430 
DSL   C39 H39  sing N N 431 
DSL   C40 H401 sing N Z 432 
DSL   C40 H402 sing N N 433 
DSL   C41 H411 sing N N 434 
DSL   C41 H412 sing N N 435 
DSL   C43 H431 sing N N 436 
DSL   C43 H432 sing N N 437 
DSL   C43 H433 sing N N 438 
DSL   C44 H44  sing N N 439 
DSL   C45 H451 sing N N 440 
DSL   C45 H452 sing N N 441 
DSL   C46 H461 sing N N 442 
DSL   C46 H462 sing N N 443 
DSL   C48 H481 sing N N 444 
DSL   C48 H482 sing N Z 445 
DSL   C48 H483 sing N N 446 
DSL   C49 H49  sing N N 447 
DSL   C50 H501 sing N N 448 
DSL   C50 H502 sing N N 449 
DSL   C51 H511 sing N N 450 
DSL   C51 H512 sing N N 451 
DSL   C53 H531 sing N N 452 
DSL   C53 H532 sing N N 453 
DSL   C53 H533 sing N N 454 
DSL   C54 H54  sing N N 455 
DSL   C55 H551 sing N N 456 
DSL   C55 H552 sing N N 457 
DSL   O60 H60  sing N N 458 
DSL   O59 H59  sing N N 459 
GLN   N   CA   sing N N 460 
GLN   N   H    sing N N 461 
GLN   N   H2   sing N N 462 
GLN   CA  C    sing N N 463 
GLN   CA  CB   sing N N 464 
GLN   CA  HA   sing N N 465 
GLN   C   O    doub N N 466 
GLN   C   OXT  sing N N 467 
GLN   CB  CG   sing N N 468 
GLN   CB  HB2  sing N N 469 
GLN   CB  HB3  sing N N 470 
GLN   CG  CD   sing N N 471 
GLN   CG  HG2  sing N N 472 
GLN   CG  HG3  sing N N 473 
GLN   CD  OE1  doub N N 474 
GLN   CD  NE2  sing N N 475 
GLN   NE2 HE21 sing N N 476 
GLN   NE2 HE22 sing N N 477 
GLN   OXT HXT  sing N N 478 
GLU   N   CA   sing N N 479 
GLU   N   H    sing N N 480 
GLU   N   H2   sing N N 481 
GLU   CA  C    sing N N 482 
GLU   CA  CB   sing N N 483 
GLU   CA  HA   sing N N 484 
GLU   C   O    doub N N 485 
GLU   C   OXT  sing N N 486 
GLU   CB  CG   sing N N 487 
GLU   CB  HB2  sing N N 488 
GLU   CB  HB3  sing N N 489 
GLU   CG  CD   sing N N 490 
GLU   CG  HG2  sing N N 491 
GLU   CG  HG3  sing N N 492 
GLU   CD  OE1  doub N N 493 
GLU   CD  OE2  sing N N 494 
GLU   OE2 HE2  sing N N 495 
GLU   OXT HXT  sing N N 496 
GLY   N   CA   sing N N 497 
GLY   N   H    sing N N 498 
GLY   N   H2   sing N N 499 
GLY   CA  C    sing N N 500 
GLY   CA  HA2  sing N N 501 
GLY   CA  HA3  sing N N 502 
GLY   C   O    doub N N 503 
GLY   C   OXT  sing N N 504 
GLY   OXT HXT  sing N N 505 
HIS   N   CA   sing N N 506 
HIS   N   H    sing N N 507 
HIS   N   H2   sing N N 508 
HIS   CA  C    sing N N 509 
HIS   CA  CB   sing N N 510 
HIS   CA  HA   sing N N 511 
HIS   C   O    doub N N 512 
HIS   C   OXT  sing N N 513 
HIS   CB  CG   sing N N 514 
HIS   CB  HB2  sing N N 515 
HIS   CB  HB3  sing N N 516 
HIS   CG  ND1  sing Y N 517 
HIS   CG  CD2  doub Y N 518 
HIS   ND1 CE1  doub Y N 519 
HIS   ND1 HD1  sing N N 520 
HIS   CD2 NE2  sing Y N 521 
HIS   CD2 HD2  sing N N 522 
HIS   CE1 NE2  sing Y N 523 
HIS   CE1 HE1  sing N N 524 
HIS   NE2 HE2  sing N N 525 
HIS   OXT HXT  sing N N 526 
ILE   N   CA   sing N N 527 
ILE   N   H    sing N N 528 
ILE   N   H2   sing N N 529 
ILE   CA  C    sing N N 530 
ILE   CA  CB   sing N N 531 
ILE   CA  HA   sing N N 532 
ILE   C   O    doub N N 533 
ILE   C   OXT  sing N N 534 
ILE   CB  CG1  sing N N 535 
ILE   CB  CG2  sing N N 536 
ILE   CB  HB   sing N N 537 
ILE   CG1 CD1  sing N N 538 
ILE   CG1 HG12 sing N N 539 
ILE   CG1 HG13 sing N N 540 
ILE   CG2 HG21 sing N N 541 
ILE   CG2 HG22 sing N N 542 
ILE   CG2 HG23 sing N N 543 
ILE   CD1 HD11 sing N N 544 
ILE   CD1 HD12 sing N N 545 
ILE   CD1 HD13 sing N N 546 
ILE   OXT HXT  sing N N 547 
LEU   N   CA   sing N N 548 
LEU   N   H    sing N N 549 
LEU   N   H2   sing N N 550 
LEU   CA  C    sing N N 551 
LEU   CA  CB   sing N N 552 
LEU   CA  HA   sing N N 553 
LEU   C   O    doub N N 554 
LEU   C   OXT  sing N N 555 
LEU   CB  CG   sing N N 556 
LEU   CB  HB2  sing N N 557 
LEU   CB  HB3  sing N N 558 
LEU   CG  CD1  sing N N 559 
LEU   CG  CD2  sing N N 560 
LEU   CG  HG   sing N N 561 
LEU   CD1 HD11 sing N N 562 
LEU   CD1 HD12 sing N N 563 
LEU   CD1 HD13 sing N N 564 
LEU   CD2 HD21 sing N N 565 
LEU   CD2 HD22 sing N N 566 
LEU   CD2 HD23 sing N N 567 
LEU   OXT HXT  sing N N 568 
LYS   N   CA   sing N N 569 
LYS   N   H    sing N N 570 
LYS   N   H2   sing N N 571 
LYS   CA  C    sing N N 572 
LYS   CA  CB   sing N N 573 
LYS   CA  HA   sing N N 574 
LYS   C   O    doub N N 575 
LYS   C   OXT  sing N N 576 
LYS   CB  CG   sing N N 577 
LYS   CB  HB2  sing N N 578 
LYS   CB  HB3  sing N N 579 
LYS   CG  CD   sing N N 580 
LYS   CG  HG2  sing N N 581 
LYS   CG  HG3  sing N N 582 
LYS   CD  CE   sing N N 583 
LYS   CD  HD2  sing N N 584 
LYS   CD  HD3  sing N N 585 
LYS   CE  NZ   sing N N 586 
LYS   CE  HE2  sing N N 587 
LYS   CE  HE3  sing N N 588 
LYS   NZ  HZ1  sing N N 589 
LYS   NZ  HZ2  sing N N 590 
LYS   NZ  HZ3  sing N N 591 
LYS   OXT HXT  sing N N 592 
MET   N   CA   sing N N 593 
MET   N   H    sing N N 594 
MET   N   H2   sing N N 595 
MET   CA  C    sing N N 596 
MET   CA  CB   sing N N 597 
MET   CA  HA   sing N N 598 
MET   C   O    doub N N 599 
MET   C   OXT  sing N N 600 
MET   CB  CG   sing N N 601 
MET   CB  HB2  sing N N 602 
MET   CB  HB3  sing N N 603 
MET   CG  SD   sing N N 604 
MET   CG  HG2  sing N N 605 
MET   CG  HG3  sing N N 606 
MET   SD  CE   sing N N 607 
MET   CE  HE1  sing N N 608 
MET   CE  HE2  sing N N 609 
MET   CE  HE3  sing N N 610 
MET   OXT HXT  sing N N 611 
PHE   N   CA   sing N N 612 
PHE   N   H    sing N N 613 
PHE   N   H2   sing N N 614 
PHE   CA  C    sing N N 615 
PHE   CA  CB   sing N N 616 
PHE   CA  HA   sing N N 617 
PHE   C   O    doub N N 618 
PHE   C   OXT  sing N N 619 
PHE   CB  CG   sing N N 620 
PHE   CB  HB2  sing N N 621 
PHE   CB  HB3  sing N N 622 
PHE   CG  CD1  doub Y N 623 
PHE   CG  CD2  sing Y N 624 
PHE   CD1 CE1  sing Y N 625 
PHE   CD1 HD1  sing N N 626 
PHE   CD2 CE2  doub Y N 627 
PHE   CD2 HD2  sing N N 628 
PHE   CE1 CZ   doub Y N 629 
PHE   CE1 HE1  sing N N 630 
PHE   CE2 CZ   sing Y N 631 
PHE   CE2 HE2  sing N N 632 
PHE   CZ  HZ   sing N N 633 
PHE   OXT HXT  sing N N 634 
PRO   N   CA   sing N N 635 
PRO   N   CD   sing N N 636 
PRO   N   H    sing N N 637 
PRO   CA  C    sing N N 638 
PRO   CA  CB   sing N N 639 
PRO   CA  HA   sing N N 640 
PRO   C   O    doub N N 641 
PRO   C   OXT  sing N N 642 
PRO   CB  CG   sing N N 643 
PRO   CB  HB2  sing N N 644 
PRO   CB  HB3  sing N N 645 
PRO   CG  CD   sing N N 646 
PRO   CG  HG2  sing N N 647 
PRO   CG  HG3  sing N N 648 
PRO   CD  HD2  sing N N 649 
PRO   CD  HD3  sing N N 650 
PRO   OXT HXT  sing N N 651 
SER   N   CA   sing N N 652 
SER   N   H    sing N N 653 
SER   N   H2   sing N N 654 
SER   CA  C    sing N N 655 
SER   CA  CB   sing N N 656 
SER   CA  HA   sing N N 657 
SER   C   O    doub N N 658 
SER   C   OXT  sing N N 659 
SER   CB  OG   sing N N 660 
SER   CB  HB2  sing N N 661 
SER   CB  HB3  sing N N 662 
SER   OG  HG   sing N N 663 
SER   OXT HXT  sing N N 664 
THR   N   CA   sing N N 665 
THR   N   H    sing N N 666 
THR   N   H2   sing N N 667 
THR   CA  C    sing N N 668 
THR   CA  CB   sing N N 669 
THR   CA  HA   sing N N 670 
THR   C   O    doub N N 671 
THR   C   OXT  sing N N 672 
THR   CB  OG1  sing N N 673 
THR   CB  CG2  sing N N 674 
THR   CB  HB   sing N N 675 
THR   OG1 HG1  sing N N 676 
THR   CG2 HG21 sing N N 677 
THR   CG2 HG22 sing N N 678 
THR   CG2 HG23 sing N N 679 
THR   OXT HXT  sing N N 680 
TRP   N   CA   sing N N 681 
TRP   N   H    sing N N 682 
TRP   N   H2   sing N N 683 
TRP   CA  C    sing N N 684 
TRP   CA  CB   sing N N 685 
TRP   CA  HA   sing N N 686 
TRP   C   O    doub N N 687 
TRP   C   OXT  sing N N 688 
TRP   CB  CG   sing N N 689 
TRP   CB  HB2  sing N N 690 
TRP   CB  HB3  sing N N 691 
TRP   CG  CD1  doub Y N 692 
TRP   CG  CD2  sing Y N 693 
TRP   CD1 NE1  sing Y N 694 
TRP   CD1 HD1  sing N N 695 
TRP   CD2 CE2  doub Y N 696 
TRP   CD2 CE3  sing Y N 697 
TRP   NE1 CE2  sing Y N 698 
TRP   NE1 HE1  sing N N 699 
TRP   CE2 CZ2  sing Y N 700 
TRP   CE3 CZ3  doub Y N 701 
TRP   CE3 HE3  sing N N 702 
TRP   CZ2 CH2  doub Y N 703 
TRP   CZ2 HZ2  sing N N 704 
TRP   CZ3 CH2  sing Y N 705 
TRP   CZ3 HZ3  sing N N 706 
TRP   CH2 HH2  sing N N 707 
TRP   OXT HXT  sing N N 708 
TYR   N   CA   sing N N 709 
TYR   N   H    sing N N 710 
TYR   N   H2   sing N N 711 
TYR   CA  C    sing N N 712 
TYR   CA  CB   sing N N 713 
TYR   CA  HA   sing N N 714 
TYR   C   O    doub N N 715 
TYR   C   OXT  sing N N 716 
TYR   CB  CG   sing N N 717 
TYR   CB  HB2  sing N N 718 
TYR   CB  HB3  sing N N 719 
TYR   CG  CD1  doub Y N 720 
TYR   CG  CD2  sing Y N 721 
TYR   CD1 CE1  sing Y N 722 
TYR   CD1 HD1  sing N N 723 
TYR   CD2 CE2  doub Y N 724 
TYR   CD2 HD2  sing N N 725 
TYR   CE1 CZ   doub Y N 726 
TYR   CE1 HE1  sing N N 727 
TYR   CE2 CZ   sing Y N 728 
TYR   CE2 HE2  sing N N 729 
TYR   CZ  OH   sing N N 730 
TYR   OH  HH   sing N N 731 
TYR   OXT HXT  sing N N 732 
VAL   N   CA   sing N N 733 
VAL   N   H    sing N N 734 
VAL   N   H2   sing N N 735 
VAL   CA  C    sing N N 736 
VAL   CA  CB   sing N N 737 
VAL   CA  HA   sing N N 738 
VAL   C   O    doub N N 739 
VAL   C   OXT  sing N N 740 
VAL   CB  CG1  sing N N 741 
VAL   CB  CG2  sing N N 742 
VAL   CB  HB   sing N N 743 
VAL   CG1 HG11 sing N N 744 
VAL   CG1 HG12 sing N N 745 
VAL   CG1 HG13 sing N N 746 
VAL   CG2 HG21 sing N N 747 
VAL   CG2 HG22 sing N N 748 
VAL   CG2 HG23 sing N N 749 
VAL   OXT HXT  sing N N 750 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-12 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9DM5 
_em_admin.last_update        2025-06-25 
_em_admin.map_release_date   2025-06-25 
_em_admin.title              'Product-Bound mannosyltransferase PimE' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          36809 
_em_entity_assembly_naturalsource.organism             'Mycobacteroides abscessus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         58 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9DM5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY   A 1 21  ? 151.265 167.486 162.792 1.00 47.12 ?  21  GLY   A N   1 
ATOM   2    C CA  . GLY   A 1 21  ? 151.215 166.037 162.755 1.00 47.12 ?  21  GLY   A CA  1 
ATOM   3    C C   . GLY   A 1 21  ? 152.159 165.390 163.749 1.00 47.12 ?  21  GLY   A C   1 
ATOM   4    O O   . GLY   A 1 21  ? 153.321 165.133 163.440 1.00 47.12 ?  21  GLY   A O   1 
ATOM   5    N N   . ALA   A 1 22  ? 151.654 165.127 164.957 1.00 48.45 ?  22  ALA   A N   1 
ATOM   6    C CA  . ALA   A 1 22  ? 152.478 164.486 165.976 1.00 48.45 ?  22  ALA   A CA  1 
ATOM   7    C C   . ALA   A 1 22  ? 152.747 163.025 165.643 1.00 48.45 ?  22  ALA   A C   1 
ATOM   8    O O   . ALA   A 1 22  ? 153.771 162.474 166.063 1.00 48.45 ?  22  ALA   A O   1 
ATOM   9    C CB  . ALA   A 1 22  ? 151.805 164.602 167.343 1.00 48.45 ?  22  ALA   A CB  1 
ATOM   10   N N   . SER   A 1 23  ? 151.844 162.380 164.903 1.00 48.57 ?  23  SER   A N   1 
ATOM   11   C CA  . SER   A 1 23  ? 152.072 160.995 164.510 1.00 48.57 ?  23  SER   A CA  1 
ATOM   12   C C   . SER   A 1 23  ? 153.329 160.875 163.659 1.00 48.57 ?  23  SER   A C   1 
ATOM   13   O O   . SER   A 1 23  ? 154.177 160.010 163.901 1.00 48.57 ?  23  SER   A O   1 
ATOM   14   C CB  . SER   A 1 23  ? 150.853 160.458 163.759 1.00 48.57 ?  23  SER   A CB  1 
ATOM   15   O OG  . SER   A 1 23  ? 150.499 161.311 162.684 1.00 48.57 ?  23  SER   A OG  1 
ATOM   16   N N   . ALA   A 1 24  ? 153.472 161.748 162.659 1.00 46.15 ?  24  ALA   A N   1 
ATOM   17   C CA  . ALA   A 1 24  ? 154.685 161.746 161.850 1.00 46.15 ?  24  ALA   A CA  1 
ATOM   18   C C   . ALA   A 1 24  ? 155.907 162.086 162.690 1.00 46.15 ?  24  ALA   A C   1 
ATOM   19   O O   . ALA   A 1 24  ? 157.003 161.582 162.426 1.00 46.15 ?  24  ALA   A O   1 
ATOM   20   C CB  . ALA   A 1 24  ? 154.546 162.732 160.692 1.00 46.15 ?  24  ALA   A CB  1 
ATOM   21   N N   . TRP   A 1 25  ? 155.739 162.938 163.702 1.00 47.64 ?  25  TRP   A N   1 
ATOM   22   C CA  . TRP   A 1 25  ? 156.845 163.254 164.597 1.00 47.64 ?  25  TRP   A CA  1 
ATOM   23   C C   . TRP   A 1 25  ? 157.319 162.011 165.338 1.00 47.64 ?  25  TRP   A C   1 
ATOM   24   O O   . TRP   A 1 25  ? 158.525 161.752 165.429 1.00 47.64 ?  25  TRP   A O   1 
ATOM   25   C CB  . TRP   A 1 25  ? 156.409 164.346 165.573 1.00 47.64 ?  25  TRP   A CB  1 
ATOM   26   C CG  . TRP   A 1 25  ? 157.453 164.767 166.551 1.00 47.64 ?  25  TRP   A CG  1 
ATOM   27   C CD1 . TRP   A 1 25  ? 158.800 164.811 166.350 1.00 47.64 ?  25  TRP   A CD1 1 
ATOM   28   C CD2 . TRP   A 1 25  ? 157.231 165.227 167.888 1.00 47.64 ?  25  TRP   A CD2 1 
ATOM   29   N NE1 . TRP   A 1 25  ? 159.433 165.261 167.484 1.00 47.64 ?  25  TRP   A NE1 1 
ATOM   30   C CE2 . TRP   A 1 25  ? 158.490 165.526 168.442 1.00 47.64 ?  25  TRP   A CE2 1 
ATOM   31   C CE3 . TRP   A 1 25  ? 156.088 165.412 168.673 1.00 47.64 ?  25  TRP   A CE3 1 
ATOM   32   C CZ2 . TRP   A 1 25  ? 158.639 165.995 169.744 1.00 47.64 ?  25  TRP   A CZ2 1 
ATOM   33   C CZ3 . TRP   A 1 25  ? 156.238 165.879 169.964 1.00 47.64 ?  25  TRP   A CZ3 1 
ATOM   34   C CH2 . TRP   A 1 25  ? 157.504 166.166 170.487 1.00 47.64 ?  25  TRP   A CH2 1 
ATOM   35   N N   . ARG   A 1 26  ? 156.383 161.215 165.856 1.00 46.58 ?  26  ARG   A N   1 
ATOM   36   C CA  . ARG   A 1 26  ? 156.757 159.961 166.502 1.00 46.58 ?  26  ARG   A CA  1 
ATOM   37   C C   . ARG   A 1 26  ? 157.407 159.009 165.505 1.00 46.58 ?  26  ARG   A C   1 
ATOM   38   O O   . ARG   A 1 26  ? 158.401 158.345 165.824 1.00 46.58 ?  26  ARG   A O   1 
ATOM   39   C CB  . ARG   A 1 26  ? 155.522 159.323 167.147 1.00 46.58 ?  26  ARG   A CB  1 
ATOM   40   C CG  . ARG   A 1 26  ? 155.655 157.848 167.531 1.00 46.58 ?  26  ARG   A CG  1 
ATOM   41   C CD  . ARG   A 1 26  ? 154.289 157.194 167.671 1.00 46.58 ?  26  ARG   A CD  1 
ATOM   42   N NE  . ARG   A 1 26  ? 153.828 156.606 166.418 1.00 46.58 ?  26  ARG   A NE  1 
ATOM   43   C CZ  . ARG   A 1 26  ? 154.059 155.355 166.039 1.00 46.58 ?  26  ARG   A CZ  1 
ATOM   44   N NH1 . ARG   A 1 26  ? 154.763 154.522 166.787 1.00 46.58 1  26  ARG   A NH1 1 
ATOM   45   N NH2 . ARG   A 1 26  ? 153.572 154.931 164.877 1.00 46.58 ?  26  ARG   A NH2 1 
ATOM   46   N N   . ARG   A 1 27  ? 156.857 158.927 164.292 1.00 46.14 ?  27  ARG   A N   1 
ATOM   47   C CA  . ARG   A 1 27  ? 157.409 158.017 163.293 1.00 46.14 ?  27  ARG   A CA  1 
ATOM   48   C C   . ARG   A 1 27  ? 158.853 158.371 162.970 1.00 46.14 ?  27  ARG   A C   1 
ATOM   49   O O   . ARG   A 1 27  ? 159.707 157.483 162.859 1.00 46.14 ?  27  ARG   A O   1 
ATOM   50   C CB  . ARG   A 1 27  ? 156.560 158.043 162.021 1.00 46.14 ?  27  ARG   A CB  1 
ATOM   51   C CG  . ARG   A 1 27  ? 155.060 157.915 162.248 1.00 46.14 ?  27  ARG   A CG  1 
ATOM   52   C CD  . ARG   A 1 27  ? 154.510 156.603 161.725 1.00 46.14 ?  27  ARG   A CD  1 
ATOM   53   N NE  . ARG   A 1 27  ? 153.070 156.507 161.940 1.00 46.14 ?  27  ARG   A NE  1 
ATOM   54   C CZ  . ARG   A 1 27  ? 152.147 156.756 161.020 1.00 46.14 ?  27  ARG   A CZ  1 
ATOM   55   N NH1 . ARG   A 1 27  ? 152.471 157.131 159.793 1.00 46.14 1  27  ARG   A NH1 1 
ATOM   56   N NH2 . ARG   A 1 27  ? 150.863 156.631 161.342 1.00 46.14 ?  27  ARG   A NH2 1 
ATOM   57   N N   . VAL   A 1 28  ? 159.147 159.663 162.808 1.00 45.24 ?  28  VAL   A N   1 
ATOM   58   C CA  . VAL   A 1 28  ? 160.520 160.068 162.524 1.00 45.24 ?  28  VAL   A CA  1 
ATOM   59   C C   . VAL   A 1 28  ? 161.403 159.875 163.749 1.00 45.24 ?  28  VAL   A C   1 
ATOM   60   O O   . VAL   A 1 28  ? 162.584 159.531 163.617 1.00 45.24 ?  28  VAL   A O   1 
ATOM   61   C CB  . VAL   A 1 28  ? 160.580 161.519 162.008 1.00 45.24 ?  28  VAL   A CB  1 
ATOM   62   C CG1 . VAL   A 1 28  ? 159.785 161.658 160.717 1.00 45.24 ?  28  VAL   A CG1 1 
ATOM   63   C CG2 . VAL   A 1 28  ? 160.076 162.495 163.055 1.00 45.24 ?  28  VAL   A CG2 1 
ATOM   64   N N   . ARG   A 1 29  ? 160.868 160.084 164.954 1.00 44.49 ?  29  ARG   A N   1 
ATOM   65   C CA  . ARG   A 1 29  ? 161.660 159.810 166.149 1.00 44.49 ?  29  ARG   A CA  1 
ATOM   66   C C   . ARG   A 1 29  ? 162.106 158.356 166.172 1.00 44.49 ?  29  ARG   A C   1 
ATOM   67   O O   . ARG   A 1 29  ? 163.284 158.059 166.393 1.00 44.49 ?  29  ARG   A O   1 
ATOM   68   C CB  . ARG   A 1 29  ? 160.863 160.145 167.409 1.00 44.49 ?  29  ARG   A CB  1 
ATOM   69   C CG  . ARG   A 1 29  ? 161.438 159.515 168.674 1.00 44.49 ?  29  ARG   A CG  1 
ATOM   70   C CD  . ARG   A 1 29  ? 160.804 160.048 169.954 1.00 44.49 ?  29  ARG   A CD  1 
ATOM   71   N NE  . ARG   A 1 29  ? 159.359 160.229 169.855 1.00 44.49 ?  29  ARG   A NE  1 
ATOM   72   C CZ  . ARG   A 1 29  ? 158.760 161.350 169.474 1.00 44.49 ?  29  ARG   A CZ  1 
ATOM   73   N NH1 . ARG   A 1 29  ? 159.452 162.425 169.133 1.00 44.49 1  29  ARG   A NH1 1 
ATOM   74   N NH2 . ARG   A 1 29  ? 157.432 161.395 169.439 1.00 44.49 ?  29  ARG   A NH2 1 
ATOM   75   N N   . ALA   A 1 30  ? 161.176 157.433 165.919 1.00 44.77 ?  30  ALA   A N   1 
ATOM   76   C CA  . ALA   A 1 30  ? 161.540 156.021 165.886 1.00 44.77 ?  30  ALA   A CA  1 
ATOM   77   C C   . ALA   A 1 30  ? 162.611 155.749 164.841 1.00 44.77 ?  30  ALA   A C   1 
ATOM   78   O O   . ALA   A 1 30  ? 163.408 154.818 164.999 1.00 44.77 ?  30  ALA   A O   1 
ATOM   79   C CB  . ALA   A 1 30  ? 160.304 155.164 165.613 1.00 44.77 ?  30  ALA   A CB  1 
ATOM   80   N N   . TRP   A 1 31  ? 162.645 156.540 163.774 1.00 42.17 ?  31  TRP   A N   1 
ATOM   81   C CA  . TRP   A 1 31  ? 163.676 156.421 162.745 1.00 42.17 ?  31  TRP   A CA  1 
ATOM   82   C C   . TRP   A 1 31  ? 164.857 157.339 163.040 1.00 42.17 ?  31  TRP   A C   1 
ATOM   83   O O   . TRP   A 1 31  ? 165.270 158.140 162.206 1.00 42.17 ?  31  TRP   A O   1 
ATOM   84   C CB  . TRP   A 1 31  ? 163.077 156.726 161.379 1.00 42.17 ?  31  TRP   A CB  1 
ATOM   85   C CG  . TRP   A 1 31  ? 162.444 155.544 160.730 1.00 42.17 ?  31  TRP   A CG  1 
ATOM   86   C CD1 . TRP   A 1 31  ? 161.154 155.132 160.863 1.00 42.17 ?  31  TRP   A CD1 1 
ATOM   87   C CD2 . TRP   A 1 31  ? 163.071 154.619 159.837 1.00 42.17 ?  31  TRP   A CD2 1 
ATOM   88   N NE1 . TRP   A 1 31  ? 160.937 154.005 160.110 1.00 42.17 ?  31  TRP   A NE1 1 
ATOM   89   C CE2 . TRP   A 1 31  ? 162.100 153.670 159.470 1.00 42.17 ?  31  TRP   A CE2 1 
ATOM   90   C CE3 . TRP   A 1 31  ? 164.360 154.501 159.314 1.00 42.17 ?  31  TRP   A CE3 1 
ATOM   91   C CZ2 . TRP   A 1 31  ? 162.375 152.619 158.606 1.00 42.17 ?  31  TRP   A CZ2 1 
ATOM   92   C CZ3 . TRP   A 1 31  ? 164.632 153.456 158.455 1.00 42.17 ?  31  TRP   A CZ3 1 
ATOM   93   C CH2 . TRP   A 1 31  ? 163.644 152.528 158.109 1.00 42.17 ?  31  TRP   A CH2 1 
ATOM   94   N N   . GLY   A 1 32  ? 165.404 157.235 164.246 1.00 41.58 ?  32  GLY   A N   1 
ATOM   95   C CA  . GLY   A 1 32  ? 166.538 158.039 164.634 1.00 41.58 ?  32  GLY   A CA  1 
ATOM   96   C C   . GLY   A 1 32  ? 167.873 157.389 164.333 1.00 41.58 ?  32  GLY   A C   1 
ATOM   97   O O   . GLY   A 1 32  ? 168.696 157.929 163.589 1.00 41.58 ?  32  GLY   A O   1 
ATOM   98   N N   . PRO   A 1 33  ? 168.115 156.211 164.910 1.00 42.57 ?  33  PRO   A N   1 
ATOM   99   C CA  . PRO   A 1 33  ? 169.423 155.570 164.706 1.00 42.57 ?  33  PRO   A CA  1 
ATOM   100  C C   . PRO   A 1 33  ? 169.749 155.353 163.245 1.00 42.57 ?  33  PRO   A C   1 
ATOM   101  O O   . PRO   A 1 33  ? 170.899 155.548 162.833 1.00 42.57 ?  33  PRO   A O   1 
ATOM   102  C CB  . PRO   A 1 33  ? 169.282 154.245 165.468 1.00 42.57 ?  33  PRO   A CB  1 
ATOM   103  C CG  . PRO   A 1 33  ? 168.211 154.492 166.472 1.00 42.57 ?  33  PRO   A CG  1 
ATOM   104  C CD  . PRO   A 1 33  ? 167.253 155.432 165.813 1.00 42.57 ?  33  PRO   A CD  1 
ATOM   105  N N   . TRP   A 1 34  ? 168.758 154.984 162.439 1.00 43.55 ?  34  TRP   A N   1 
ATOM   106  C CA  . TRP   A 1 34  ? 168.956 154.758 161.016 1.00 43.55 ?  34  TRP   A CA  1 
ATOM   107  C C   . TRP   A 1 34  ? 168.722 156.017 160.188 1.00 43.55 ?  34  TRP   A C   1 
ATOM   108  O O   . TRP   A 1 34  ? 168.524 155.924 158.972 1.00 43.55 ?  34  TRP   A O   1 
ATOM   109  C CB  . TRP   A 1 34  ? 168.052 153.618 160.545 1.00 43.55 ?  34  TRP   A CB  1 
ATOM   110  C CG  . TRP   A 1 34  ? 168.486 152.289 161.094 1.00 43.55 ?  34  TRP   A CG  1 
ATOM   111  C CD1 . TRP   A 1 34  ? 168.680 151.972 162.405 1.00 43.55 ?  34  TRP   A CD1 1 
ATOM   112  C CD2 . TRP   A 1 34  ? 168.787 151.106 160.347 1.00 43.55 ?  34  TRP   A CD2 1 
ATOM   113  N NE1 . TRP   A 1 34  ? 169.080 150.666 162.522 1.00 43.55 ?  34  TRP   A NE1 1 
ATOM   114  C CE2 . TRP   A 1 34  ? 169.153 150.112 161.273 1.00 43.55 ?  34  TRP   A CE2 1 
ATOM   115  C CE3 . TRP   A 1 34  ? 168.781 150.791 158.986 1.00 43.55 ?  34  TRP   A CE3 1 
ATOM   116  C CZ2 . TRP   A 1 34  ? 169.509 148.824 160.882 1.00 43.55 ?  34  TRP   A CZ2 1 
ATOM   117  C CZ3 . TRP   A 1 34  ? 169.135 149.512 158.600 1.00 43.55 ?  34  TRP   A CZ3 1 
ATOM   118  C CH2 . TRP   A 1 34  ? 169.494 148.545 159.544 1.00 43.55 ?  34  TRP   A CH2 1 
ATOM   119  N N   . LEU   A 1 35  ? 168.727 157.185 160.825 1.00 40.59 ?  35  LEU   A N   1 
ATOM   120  C CA  . LEU   A 1 35  ? 168.872 158.469 160.154 1.00 40.59 ?  35  LEU   A CA  1 
ATOM   121  C C   . LEU   A 1 35  ? 170.172 159.161 160.524 1.00 40.59 ?  35  LEU   A C   1 
ATOM   122  O O   . LEU   A 1 35  ? 170.837 159.732 159.655 1.00 40.59 ?  35  LEU   A O   1 
ATOM   123  C CB  . LEU   A 1 35  ? 167.691 159.378 160.499 1.00 40.59 ?  35  LEU   A CB  1 
ATOM   124  C CG  . LEU   A 1 35  ? 167.683 160.771 159.871 1.00 40.59 ?  35  LEU   A CG  1 
ATOM   125  C CD1 . LEU   A 1 35  ? 167.903 160.691 158.368 1.00 40.59 ?  35  LEU   A CD1 1 
ATOM   126  C CD2 . LEU   A 1 35  ? 166.374 161.484 160.188 1.00 40.59 ?  35  LEU   A CD2 1 
ATOM   127  N N   . LEU   A 1 36  ? 170.569 159.092 161.798 1.00 39.74 ?  36  LEU   A N   1 
ATOM   128  C CA  . LEU   A 1 36  ? 171.906 159.533 162.184 1.00 39.74 ?  36  LEU   A CA  1 
ATOM   129  C C   . LEU   A 1 36  ? 172.979 158.662 161.544 1.00 39.74 ?  36  LEU   A C   1 
ATOM   130  O O   . LEU   A 1 36  ? 174.029 159.165 161.132 1.00 39.74 ?  36  LEU   A O   1 
ATOM   131  C CB  . LEU   A 1 36  ? 172.051 159.518 163.704 1.00 39.74 ?  36  LEU   A CB  1 
ATOM   132  C CG  . LEU   A 1 36  ? 173.402 159.989 164.248 1.00 39.74 ?  36  LEU   A CG  1 
ATOM   133  C CD1 . LEU   A 1 36  ? 173.897 161.229 163.530 1.00 39.74 ?  36  LEU   A CD1 1 
ATOM   134  C CD2 . LEU   A 1 36  ? 173.314 160.242 165.740 1.00 39.74 ?  36  LEU   A CD2 1 
ATOM   135  N N   . GLY   A 1 37  ? 172.745 157.352 161.464 1.00 38.68 ?  37  GLY   A N   1 
ATOM   136  C CA  . GLY   A 1 37  ? 173.682 156.503 160.751 1.00 38.68 ?  37  GLY   A CA  1 
ATOM   137  C C   . GLY   A 1 37  ? 173.852 156.931 159.308 1.00 38.68 ?  37  GLY   A C   1 
ATOM   138  O O   . GLY   A 1 37  ? 174.971 156.991 158.794 1.00 38.68 ?  37  GLY   A O   1 
ATOM   139  N N   . LEU   A 1 38  ? 172.742 157.251 158.640 1.00 40.03 ?  38  LEU   A N   1 
ATOM   140  C CA  . LEU   A 1 38  ? 172.813 157.722 157.261 1.00 40.03 ?  38  LEU   A CA  1 
ATOM   141  C C   . LEU   A 1 38  ? 173.578 159.036 157.166 1.00 40.03 ?  38  LEU   A C   1 
ATOM   142  O O   . LEU   A 1 38  ? 174.414 159.212 156.273 1.00 40.03 ?  38  LEU   A O   1 
ATOM   143  C CB  . LEU   A 1 38  ? 171.402 157.882 156.696 1.00 40.03 ?  38  LEU   A CB  1 
ATOM   144  C CG  . LEU   A 1 38  ? 171.280 157.951 155.174 1.00 40.03 ?  38  LEU   A CG  1 
ATOM   145  C CD1 . LEU   A 1 38  ? 169.914 157.449 154.733 1.00 40.03 ?  38  LEU   A CD1 1 
ATOM   146  C CD2 . LEU   A 1 38  ? 171.517 159.365 154.674 1.00 40.03 ?  38  LEU   A CD2 1 
ATOM   147  N N   . SER   A 1 39  ? 173.306 159.971 158.077 1.00 39.28 ?  39  SER   A N   1 
ATOM   148  C CA  . SER   A 1 39  ? 174.010 161.249 158.041 1.00 39.28 ?  39  SER   A CA  1 
ATOM   149  C C   . SER   A 1 39  ? 175.510 161.055 158.227 1.00 39.28 ?  39  SER   A C   1 
ATOM   150  O O   . SER   A 1 39  ? 176.317 161.660 157.509 1.00 39.28 ?  39  SER   A O   1 
ATOM   151  C CB  . SER   A 1 39  ? 173.460 162.184 159.116 1.00 39.28 ?  39  SER   A CB  1 
ATOM   152  O OG  . SER   A 1 39  ? 172.217 162.739 158.724 1.00 39.28 ?  39  SER   A OG  1 
ATOM   153  N N   . VAL   A 1 40  ? 175.902 160.215 159.186 1.00 39.87 ?  40  VAL   A N   1 
ATOM   154  C CA  . VAL   A 1 40  ? 177.322 159.998 159.447 1.00 39.87 ?  40  VAL   A CA  1 
ATOM   155  C C   . VAL   A 1 40  ? 177.985 159.321 158.258 1.00 39.87 ?  40  VAL   A C   1 
ATOM   156  O O   . VAL   A 1 40  ? 179.106 159.672 157.873 1.00 39.87 ?  40  VAL   A O   1 
ATOM   157  C CB  . VAL   A 1 40  ? 177.516 159.181 160.737 1.00 39.87 ?  40  VAL   A CB  1 
ATOM   158  C CG1 . VAL   A 1 40  ? 178.985 158.829 160.922 1.00 39.87 ?  40  VAL   A CG1 1 
ATOM   159  C CG2 . VAL   A 1 40  ? 176.992 159.952 161.932 1.00 39.87 ?  40  VAL   A CG2 1 
ATOM   160  N N   . ALA   A 1 41  ? 177.317 158.330 157.665 1.00 38.99 ?  41  ALA   A N   1 
ATOM   161  C CA  . ALA   A 1 41  ? 177.881 157.680 156.489 1.00 38.99 ?  41  ALA   A CA  1 
ATOM   162  C C   . ALA   A 1 41  ? 178.066 158.676 155.351 1.00 38.99 ?  41  ALA   A C   1 
ATOM   163  O O   . ALA   A 1 41  ? 179.104 158.675 154.680 1.00 38.99 ?  41  ALA   A O   1 
ATOM   164  C CB  . ALA   A 1 41  ? 176.988 156.520 156.051 1.00 38.99 ?  41  ALA   A CB  1 
ATOM   165  N N   . VAL   A 1 42  ? 177.076 159.544 155.124 1.00 38.28 ?  42  VAL   A N   1 
ATOM   166  C CA  . VAL   A 1 42  ? 177.185 160.525 154.047 1.00 38.28 ?  42  VAL   A CA  1 
ATOM   167  C C   . VAL   A 1 42  ? 178.346 161.475 154.306 1.00 38.28 ?  42  VAL   A C   1 
ATOM   168  O O   . VAL   A 1 42  ? 179.144 161.766 153.408 1.00 38.28 ?  42  VAL   A O   1 
ATOM   169  C CB  . VAL   A 1 42  ? 175.863 161.292 153.877 1.00 38.28 ?  42  VAL   A CB  1 
ATOM   170  C CG1 . VAL   A 1 42  ? 176.017 162.385 152.833 1.00 38.28 ?  42  VAL   A CG1 1 
ATOM   171  C CG2 . VAL   A 1 42  ? 174.748 160.346 153.467 1.00 38.28 ?  42  VAL   A CG2 1 
ATOM   172  N N   . ARG   A 1 43  ? 178.456 161.978 155.534 1.00 38.18 ?  43  ARG   A N   1 
ATOM   173  C CA  . ARG   A 1 43  ? 179.523 162.916 155.864 1.00 38.18 ?  43  ARG   A CA  1 
ATOM   174  C C   . ARG   A 1 43  ? 180.894 162.268 155.699 1.00 38.18 ?  43  ARG   A C   1 
ATOM   175  O O   . ARG   A 1 43  ? 181.811 162.869 155.125 1.00 38.18 ?  43  ARG   A O   1 
ATOM   176  C CB  . ARG   A 1 43  ? 179.356 163.433 157.293 1.00 38.18 ?  43  ARG   A CB  1 
ATOM   177  C CG  . ARG   A 1 43  ? 180.352 164.511 157.686 1.00 38.18 ?  43  ARG   A CG  1 
ATOM   178  C CD  . ARG   A 1 43  ? 179.986 165.848 157.076 1.00 38.18 ?  43  ARG   A CD  1 
ATOM   179  N NE  . ARG   A 1 43  ? 181.154 166.690 156.854 1.00 38.18 ?  43  ARG   A NE  1 
ATOM   180  C CZ  . ARG   A 1 43  ? 181.099 167.959 156.474 1.00 38.18 ?  43  ARG   A CZ  1 
ATOM   181  N NH1 . ARG   A 1 43  ? 179.945 168.574 156.282 1.00 38.18 1  43  ARG   A NH1 1 
ATOM   182  N NH2 . ARG   A 1 43  ? 182.232 168.627 156.283 1.00 38.18 ?  43  ARG   A NH2 1 
ATOM   183  N N   . LEU   A 1 44  ? 181.046 161.043 156.207 1.00 38.52 ?  44  LEU   A N   1 
ATOM   184  C CA  . LEU   A 1 44  ? 182.328 160.359 156.112 1.00 38.52 ?  44  LEU   A CA  1 
ATOM   185  C C   . LEU   A 1 44  ? 182.684 160.069 154.665 1.00 38.52 ?  44  LEU   A C   1 
ATOM   186  O O   . LEU   A 1 44  ? 183.848 160.183 154.270 1.00 38.52 ?  44  LEU   A O   1 
ATOM   187  C CB  . LEU   A 1 44  ? 182.294 159.061 156.922 1.00 38.52 ?  44  LEU   A CB  1 
ATOM   188  C CG  . LEU   A 1 44  ? 182.202 159.157 158.451 1.00 38.52 ?  44  LEU   A CG  1 
ATOM   189  C CD1 . LEU   A 1 44  ? 182.696 157.865 159.084 1.00 38.52 ?  44  LEU   A CD1 1 
ATOM   190  C CD2 . LEU   A 1 44  ? 182.972 160.349 159.007 1.00 38.52 ?  44  LEU   A CD2 1 
ATOM   191  N N   . ALA   A 1 45  ? 181.697 159.684 153.856 1.00 37.75 ?  45  ALA   A N   1 
ATOM   192  C CA  . ALA   A 1 45  ? 181.951 159.449 152.441 1.00 37.75 ?  45  ALA   A CA  1 
ATOM   193  C C   . ALA   A 1 45  ? 182.391 160.733 151.749 1.00 37.75 ?  45  ALA   A C   1 
ATOM   194  O O   . ALA   A 1 45  ? 183.343 160.738 150.963 1.00 37.75 ?  45  ALA   A O   1 
ATOM   195  C CB  . ALA   A 1 45  ? 180.700 158.874 151.776 1.00 37.75 ?  45  ALA   A CB  1 
ATOM   196  N N   . TRP   A 1 46  ? 181.707 161.841 152.038 1.00 37.47 ?  46  TRP   A N   1 
ATOM   197  C CA  . TRP   A 1 46  ? 182.055 163.099 151.389 1.00 37.47 ?  46  TRP   A CA  1 
ATOM   198  C C   . TRP   A 1 46  ? 183.466 163.531 151.760 1.00 37.47 ?  46  TRP   A C   1 
ATOM   199  O O   . TRP   A 1 46  ? 184.246 163.943 150.894 1.00 37.47 ?  46  TRP   A O   1 
ATOM   200  C CB  . TRP   A 1 46  ? 181.050 164.184 151.768 1.00 37.47 ?  46  TRP   A CB  1 
ATOM   201  C CG  . TRP   A 1 46  ? 181.244 165.464 151.020 1.00 37.47 ?  46  TRP   A CG  1 
ATOM   202  C CD1 . TRP   A 1 46  ? 181.154 165.642 149.673 1.00 37.47 ?  46  TRP   A CD1 1 
ATOM   203  C CD2 . TRP   A 1 46  ? 181.558 166.746 151.574 1.00 37.47 ?  46  TRP   A CD2 1 
ATOM   204  N NE1 . TRP   A 1 46  ? 181.391 166.956 149.351 1.00 37.47 ?  46  TRP   A NE1 1 
ATOM   205  C CE2 . TRP   A 1 46  ? 181.642 167.654 150.501 1.00 37.47 ?  46  TRP   A CE2 1 
ATOM   206  C CE3 . TRP   A 1 46  ? 181.776 167.215 152.872 1.00 37.47 ?  46  TRP   A CE3 1 
ATOM   207  C CZ2 . TRP   A 1 46  ? 181.936 169.002 150.686 1.00 37.47 ?  46  TRP   A CZ2 1 
ATOM   208  C CZ3 . TRP   A 1 46  ? 182.068 168.554 153.052 1.00 37.47 ?  46  TRP   A CZ3 1 
ATOM   209  C CH2 . TRP   A 1 46  ? 182.146 169.431 151.966 1.00 37.47 ?  46  TRP   A CH2 1 
ATOM   210  N N   . ALA   A 1 47  ? 183.820 163.430 153.042 1.00 37.33 ?  47  ALA   A N   1 
ATOM   211  C CA  . ALA   A 1 47  ? 185.123 163.914 153.486 1.00 37.33 ?  47  ALA   A CA  1 
ATOM   212  C C   . ALA   A 1 47  ? 186.267 163.143 152.840 1.00 37.33 ?  47  ALA   A C   1 
ATOM   213  O O   . ALA   A 1 47  ? 187.265 163.732 152.415 1.00 37.33 ?  47  ALA   A O   1 
ATOM   214  C CB  . ALA   A 1 47  ? 185.215 163.830 155.010 1.00 37.33 ?  47  ALA   A CB  1 
ATOM   215  N N   . TYR   A 1 48  ? 186.139 161.820 152.757 1.00 36.54 ?  48  TYR   A N   1 
ATOM   216  C CA  . TYR   A 1 48  ? 187.213 160.956 152.285 1.00 36.54 ?  48  TYR   A CA  1 
ATOM   217  C C   . TYR   A 1 48  ? 187.015 160.468 150.859 1.00 36.54 ?  48  TYR   A C   1 
ATOM   218  O O   . TYR   A 1 48  ? 187.703 159.532 150.440 1.00 36.54 ?  48  TYR   A O   1 
ATOM   219  C CB  . TYR   A 1 48  ? 187.372 159.758 153.226 1.00 36.54 ?  48  TYR   A CB  1 
ATOM   220  C CG  . TYR   A 1 48  ? 187.803 160.165 154.612 1.00 36.54 ?  48  TYR   A CG  1 
ATOM   221  C CD1 . TYR   A 1 48  ? 186.873 160.522 155.573 1.00 36.54 ?  48  TYR   A CD1 1 
ATOM   222  C CD2 . TYR   A 1 48  ? 189.146 160.216 154.950 1.00 36.54 ?  48  TYR   A CD2 1 
ATOM   223  C CE1 . TYR   A 1 48  ? 187.267 160.908 156.835 1.00 36.54 ?  48  TYR   A CE1 1 
ATOM   224  C CE2 . TYR   A 1 48  ? 189.550 160.600 156.208 1.00 36.54 ?  48  TYR   A CE2 1 
ATOM   225  C CZ  . TYR   A 1 48  ? 188.607 160.945 157.147 1.00 36.54 ?  48  TYR   A CZ  1 
ATOM   226  O OH  . TYR   A 1 48  ? 189.011 161.329 158.402 1.00 36.54 ?  48  TYR   A OH  1 
ATOM   227  N N   . LEU   A 1 49  ? 186.093 161.063 150.106 1.00 37.54 ?  49  LEU   A N   1 
ATOM   228  C CA  . LEU   A 1 49  ? 185.989 160.785 148.679 1.00 37.54 ?  49  LEU   A CA  1 
ATOM   229  C C   . LEU   A 1 49  ? 186.280 162.010 147.826 1.00 37.54 ?  49  LEU   A C   1 
ATOM   230  O O   . LEU   A 1 49  ? 186.718 161.866 146.680 1.00 37.54 ?  49  LEU   A O   1 
ATOM   231  C CB  . LEU   A 1 49  ? 184.592 160.258 148.342 1.00 37.54 ?  49  LEU   A CB  1 
ATOM   232  C CG  . LEU   A 1 49  ? 184.258 158.866 148.882 1.00 37.54 ?  49  LEU   A CG  1 
ATOM   233  C CD1 . LEU   A 1 49  ? 182.766 158.599 148.772 1.00 37.54 ?  49  LEU   A CD1 1 
ATOM   234  C CD2 . LEU   A 1 49  ? 185.049 157.797 148.146 1.00 37.54 ?  49  LEU   A CD2 1 
ATOM   235  N N   . THR   A 1 50  ? 186.058 163.206 148.356 1.00 37.29 ?  50  THR   A N   1 
ATOM   236  C CA  . THR   A 1 50  ? 186.228 164.416 147.578 1.00 37.29 ?  50  THR   A CA  1 
ATOM   237  C C   . THR   A 1 50  ? 187.506 165.141 147.979 1.00 37.29 ?  50  THR   A C   1 
ATOM   238  O O   . THR   A 1 50  ? 187.780 165.282 149.175 1.00 37.29 ?  50  THR   A O   1 
ATOM   239  C CB  . THR   A 1 50  ? 185.046 165.366 147.780 1.00 37.29 ?  50  THR   A CB  1 
ATOM   240  O OG1 . THR   A 1 50  ? 184.973 165.748 149.158 1.00 37.29 ?  50  THR   A OG1 1 
ATOM   241  C CG2 . THR   A 1 50  ? 183.745 164.693 147.369 1.00 37.29 ?  50  THR   A CG2 1 
ATOM   242  N N   . PRO   A 1 51  ? 188.300 165.621 147.023 1.00 39.48 ?  51  PRO   A N   1 
ATOM   243  C CA  . PRO   A 1 51  ? 189.465 166.428 147.395 1.00 39.48 ?  51  PRO   A CA  1 
ATOM   244  C C   . PRO   A 1 51  ? 189.029 167.673 148.149 1.00 39.48 ?  51  PRO   A C   1 
ATOM   245  O O   . PRO   A 1 51  ? 188.016 168.295 147.826 1.00 39.48 ?  51  PRO   A O   1 
ATOM   246  C CB  . PRO   A 1 51  ? 190.109 166.773 146.048 1.00 39.48 ?  51  PRO   A CB  1 
ATOM   247  C CG  . PRO   A 1 51  ? 189.011 166.647 145.058 1.00 39.48 ?  51  PRO   A CG  1 
ATOM   248  C CD  . PRO   A 1 51  ? 188.133 165.547 145.561 1.00 39.48 ?  51  PRO   A CD  1 
ATOM   249  N N   . HIS   A 1 52  ? 189.807 168.032 149.166 1.00 39.22 ?  52  HIS   A N   1 
ATOM   250  C CA  . HIS   A 1 52  ? 189.544 169.146 150.069 1.00 39.22 ?  52  HIS   A CA  1 
ATOM   251  C C   . HIS   A 1 52  ? 188.382 168.875 151.014 1.00 39.22 ?  52  HIS   A C   1 
ATOM   252  O O   . HIS   A 1 52  ? 188.103 169.710 151.880 1.00 39.22 ?  52  HIS   A O   1 
ATOM   253  C CB  . HIS   A 1 52  ? 189.266 170.453 149.313 1.00 39.22 ?  52  HIS   A CB  1 
ATOM   254  C CG  . HIS   A 1 52  ? 190.130 170.646 148.108 1.00 39.22 ?  52  HIS   A CG  1 
ATOM   255  N ND1 . HIS   A 1 52  ? 191.500 170.772 148.187 1.00 39.22 ?  52  HIS   A ND1 1 
ATOM   256  C CD2 . HIS   A 1 52  ? 189.820 170.728 146.793 1.00 39.22 ?  52  HIS   A CD2 1 
ATOM   257  C CE1 . HIS   A 1 52  ? 191.997 170.925 146.973 1.00 39.22 ?  52  HIS   A CE1 1 
ATOM   258  N NE2 . HIS   A 1 52  ? 190.998 170.903 146.109 1.00 39.22 ?  52  HIS   A NE2 1 
ATOM   259  N N   . GLY   A 1 53  ? 187.690 167.744 150.880 1.00 39.68 ?  53  GLY   A N   1 
ATOM   260  C CA  . GLY   A 1 53  ? 186.679 167.394 151.863 1.00 39.68 ?  53  GLY   A CA  1 
ATOM   261  C C   . GLY   A 1 53  ? 187.285 167.100 153.220 1.00 39.68 ?  53  GLY   A C   1 
ATOM   262  O O   . GLY   A 1 53  ? 186.765 167.536 154.251 1.00 39.68 ?  53  GLY   A O   1 
ATOM   263  N N   . ALA   A 1 54  ? 188.390 166.354 153.240 1.00 41.19 ?  54  ALA   A N   1 
ATOM   264  C CA  . ALA   A 1 54  ? 189.158 166.097 154.451 1.00 41.19 ?  54  ALA   A CA  1 
ATOM   265  C C   . ALA   A 1 54  ? 190.379 167.001 154.549 1.00 41.19 ?  54  ALA   A C   1 
ATOM   266  O O   . ALA   A 1 54  ? 191.404 166.605 155.111 1.00 41.19 ?  54  ALA   A O   1 
ATOM   267  C CB  . ALA   A 1 54  ? 189.582 164.630 154.511 1.00 41.19 ?  54  ALA   A CB  1 
ATOM   268  N N   . ASP   A 1 55  ? 190.289 168.213 154.002 1.00 42.08 ?  55  ASP   A N   1 
ATOM   269  C CA  . ASP   A 1 55  ? 191.424 169.125 154.053 1.00 42.08 ?  55  ASP   A CA  1 
ATOM   270  C C   . ASP   A 1 55  ? 191.803 169.430 155.495 1.00 42.08 ?  55  ASP   A C   1 
ATOM   271  O O   . ASP   A 1 55  ? 192.986 169.412 155.853 1.00 42.08 ?  55  ASP   A O   1 
ATOM   272  C CB  . ASP   A 1 55  ? 191.089 170.415 153.305 1.00 42.08 ?  55  ASP   A CB  1 
ATOM   273  C CG  . ASP   A 1 55  ? 192.321 171.202 152.925 1.00 42.08 ?  55  ASP   A CG  1 
ATOM   274  O OD1 . ASP   A 1 55  ? 193.436 170.740 153.237 1.00 42.08 ?  55  ASP   A OD1 1 
ATOM   275  O OD2 . ASP   A 1 55  ? 192.174 172.280 152.312 1.00 42.08 -1 55  ASP   A OD2 1 
ATOM   276  N N   . LEU   A 1 56  ? 190.809 169.704 156.337 1.00 41.13 ?  56  LEU   A N   1 
ATOM   277  C CA  . LEU   A 1 56  ? 191.013 169.935 157.763 1.00 41.13 ?  56  LEU   A CA  1 
ATOM   278  C C   . LEU   A 1 56  ? 192.144 170.935 157.992 1.00 41.13 ?  56  LEU   A C   1 
ATOM   279  O O   . LEU   A 1 56  ? 193.194 170.619 158.551 1.00 41.13 ?  56  LEU   A O   1 
ATOM   280  C CB  . LEU   A 1 56  ? 191.289 168.616 158.486 1.00 41.13 ?  56  LEU   A CB  1 
ATOM   281  C CG  . LEU   A 1 56  ? 190.207 167.540 158.391 1.00 41.13 ?  56  LEU   A CG  1 
ATOM   282  C CD1 . LEU   A 1 56  ? 190.576 166.345 159.250 1.00 41.13 ?  56  LEU   A CD1 1 
ATOM   283  C CD2 . LEU   A 1 56  ? 188.855 168.088 158.804 1.00 41.13 ?  56  LEU   A CD2 1 
ATOM   284  N N   . VAL   A 1 57  ? 191.936 172.156 157.519 1.00 42.28 ?  57  VAL   A N   1 
ATOM   285  C CA  . VAL   A 1 57  ? 192.950 173.232 157.627 1.00 42.28 ?  57  VAL   A CA  1 
ATOM   286  C C   . VAL   A 1 57  ? 193.205 173.530 159.096 1.00 42.28 ?  57  VAL   A C   1 
ATOM   287  O O   . VAL   A 1 57  ? 194.352 173.849 159.409 1.00 42.28 ?  57  VAL   A O   1 
ATOM   288  C CB  . VAL   A 1 57  ? 192.478 174.499 156.899 1.00 42.28 ?  57  VAL   A CB  1 
ATOM   289  C CG1 . VAL   A 1 57  ? 192.104 174.218 155.455 1.00 42.28 ?  57  VAL   A CG1 1 
ATOM   290  C CG2 . VAL   A 1 57  ? 191.332 175.170 157.632 1.00 42.28 ?  57  VAL   A CG2 1 
ATOM   291  N N   . ASP   A 1 58  ? 192.199 173.458 159.966 1.00 41.51 ?  58  ASP   A N   1 
ATOM   292  C CA  . ASP   A 1 58  ? 192.371 173.848 161.393 1.00 41.51 ?  58  ASP   A CA  1 
ATOM   293  C C   . ASP   A 1 58  ? 192.866 172.643 162.196 1.00 41.51 ?  58  ASP   A C   1 
ATOM   294  O O   . ASP   A 1 58  ? 193.456 172.883 163.240 1.00 41.51 ?  58  ASP   A O   1 
ATOM   295  C CB  . ASP   A 1 58  ? 191.108 174.497 161.950 1.00 41.51 ?  58  ASP   A CB  1 
ATOM   296  C CG  . ASP   A 1 58  ? 190.718 175.785 161.251 1.00 41.51 ?  58  ASP   A CG  1 
ATOM   297  O OD1 . ASP   A 1 58  ? 191.628 176.513 160.818 1.00 41.51 ?  58  ASP   A OD1 1 
ATOM   298  O OD2 . ASP   A 1 58  ? 189.506 176.048 161.153 1.00 41.51 -1 58  ASP   A OD2 1 
ATOM   299  N N   . LEU   A 1 59  ? 192.557 171.404 161.819 1.00 41.87 ?  59  LEU   A N   1 
ATOM   300  C CA  . LEU   A 1 59  ? 193.189 170.248 162.445 1.00 41.87 ?  59  LEU   A CA  1 
ATOM   301  C C   . LEU   A 1 59  ? 194.655 170.146 162.049 1.00 41.87 ?  59  LEU   A C   1 
ATOM   302  O O   . LEU   A 1 59  ? 195.507 169.834 162.886 1.00 41.87 ?  59  LEU   A O   1 
ATOM   303  C CB  . LEU   A 1 59  ? 192.455 168.965 162.069 1.00 41.87 ?  59  LEU   A CB  1 
ATOM   304  C CG  . LEU   A 1 59  ? 192.889 167.721 162.848 1.00 41.87 ?  59  LEU   A CG  1 
ATOM   305  C CD1 . LEU   A 1 59  ? 191.725 166.767 163.020 1.00 41.87 ?  59  LEU   A CD1 1 
ATOM   306  C CD2 . LEU   A 1 59  ? 194.048 167.015 162.160 1.00 41.87 ?  59  LEU   A CD2 1 
ATOM   307  N N   . HIS   A 1 60  ? 194.971 170.392 160.778 1.00 43.13 ?  60  HIS   A N   1 
ATOM   308  C CA  . HIS   A 1 60  ? 196.369 170.388 160.374 1.00 43.13 ?  60  HIS   A CA  1 
ATOM   309  C C   . HIS   A 1 60  ? 197.143 171.491 161.071 1.00 43.13 ?  60  HIS   A C   1 
ATOM   310  O O   . HIS   A 1 60  ? 198.325 171.316 161.372 1.00 43.13 ?  60  HIS   A O   1 
ATOM   311  C CB  . HIS   A 1 60  ? 196.489 170.524 158.859 1.00 43.13 ?  60  HIS   A CB  1 
ATOM   312  C CG  . HIS   A 1 60  ? 196.323 169.231 158.127 1.00 43.13 ?  60  HIS   A CG  1 
ATOM   313  N ND1 . HIS   A 1 60  ? 195.091 168.737 157.757 1.00 43.13 ?  60  HIS   A ND1 1 
ATOM   314  C CD2 . HIS   A 1 60  ? 197.235 168.325 157.703 1.00 43.13 ?  60  HIS   A CD2 1 
ATOM   315  C CE1 . HIS   A 1 60  ? 195.251 167.583 157.135 1.00 43.13 ?  60  HIS   A CE1 1 
ATOM   316  N NE2 . HIS   A 1 60  ? 196.542 167.310 157.089 1.00 43.13 ?  60  HIS   A NE2 1 
ATOM   317  N N   . VAL   A 1 61  ? 196.503 172.628 161.346 1.00 43.09 ?  61  VAL   A N   1 
ATOM   318  C CA  . VAL   A 1 61  ? 197.162 173.673 162.124 1.00 43.09 ?  61  VAL   A CA  1 
ATOM   319  C C   . VAL   A 1 61  ? 197.431 173.183 163.541 1.00 43.09 ?  61  VAL   A C   1 
ATOM   320  O O   . VAL   A 1 61  ? 198.517 173.388 164.095 1.00 43.09 ?  61  VAL   A O   1 
ATOM   321  C CB  . VAL   A 1 61  ? 196.315 174.956 162.127 1.00 43.09 ?  61  VAL   A CB  1 
ATOM   322  C CG1 . VAL   A 1 61  ? 196.752 175.879 163.250 1.00 43.09 ?  61  VAL   A CG1 1 
ATOM   323  C CG2 . VAL   A 1 61  ? 196.417 175.653 160.789 1.00 43.09 ?  61  VAL   A CG2 1 
ATOM   324  N N   . TYR   A 1 62  ? 196.440 172.530 164.149 1.00 41.34 ?  62  TYR   A N   1 
ATOM   325  C CA  . TYR   A 1 62  ? 196.606 172.006 165.502 1.00 41.34 ?  62  TYR   A CA  1 
ATOM   326  C C   . TYR   A 1 62  ? 197.690 170.941 165.557 1.00 41.34 ?  62  TYR   A C   1 
ATOM   327  O O   . TYR   A 1 62  ? 198.308 170.736 166.606 1.00 41.34 ?  62  TYR   A O   1 
ATOM   328  C CB  . TYR   A 1 62  ? 195.286 171.422 166.004 1.00 41.34 ?  62  TYR   A CB  1 
ATOM   329  C CG  . TYR   A 1 62  ? 194.107 172.370 165.949 1.00 41.34 ?  62  TYR   A CG  1 
ATOM   330  C CD1 . TYR   A 1 62  ? 194.289 173.740 165.819 1.00 41.34 ?  62  TYR   A CD1 1 
ATOM   331  C CD2 . TYR   A 1 62  ? 192.809 171.886 165.997 1.00 41.34 ?  62  TYR   A CD2 1 
ATOM   332  C CE1 . TYR   A 1 62  ? 193.209 174.599 165.760 1.00 41.34 ?  62  TYR   A CE1 1 
ATOM   333  C CE2 . TYR   A 1 62  ? 191.728 172.735 165.936 1.00 41.34 ?  62  TYR   A CE2 1 
ATOM   334  C CZ  . TYR   A 1 62  ? 191.932 174.089 165.817 1.00 41.34 ?  62  TYR   A CZ  1 
ATOM   335  O OH  . TYR   A 1 62  ? 190.851 174.936 165.754 1.00 41.34 ?  62  TYR   A OH  1 
ATOM   336  N N   . VAL   A 1 63  ? 197.918 170.242 164.447 1.00 42.43 ?  63  VAL   A N   1 
ATOM   337  C CA  . VAL   A 1 63  ? 198.912 169.174 164.427 1.00 42.43 ?  63  VAL   A CA  1 
ATOM   338  C C   . VAL   A 1 63  ? 200.295 169.721 164.096 1.00 42.43 ?  63  VAL   A C   1 
ATOM   339  O O   . VAL   A 1 63  ? 201.309 169.186 164.556 1.00 42.43 ?  63  VAL   A O   1 
ATOM   340  C CB  . VAL   A 1 63  ? 198.488 168.082 163.431 1.00 42.43 ?  63  VAL   A CB  1 
ATOM   341  C CG1 . VAL   A 1 63  ? 199.597 167.061 163.260 1.00 42.43 ?  63  VAL   A CG1 1 
ATOM   342  C CG2 . VAL   A 1 63  ? 197.220 167.406 163.901 1.00 42.43 ?  63  VAL   A CG2 1 
ATOM   343  N N   . SER   A 1 64  ? 200.366 170.771 163.285 1.00 43.95 ?  64  SER   A N   1 
ATOM   344  C CA  . SER   A 1 64  ? 201.638 171.331 162.862 1.00 43.95 ?  64  SER   A CA  1 
ATOM   345  C C   . SER   A 1 64  ? 202.135 172.441 163.774 1.00 43.95 ?  64  SER   A C   1 
ATOM   346  O O   . SER   A 1 64  ? 203.284 172.868 163.629 1.00 43.95 ?  64  SER   A O   1 
ATOM   347  C CB  . SER   A 1 64  ? 201.527 171.867 161.432 1.00 43.95 ?  64  SER   A CB  1 
ATOM   348  O OG  . SER   A 1 64  ? 201.173 170.835 160.528 1.00 43.95 ?  64  SER   A OG  1 
ATOM   349  N N   . GLY   A 1 65  ? 201.311 172.927 164.696 1.00 44.55 ?  65  GLY   A N   1 
ATOM   350  C CA  . GLY   A 1 65  ? 201.772 173.875 165.678 1.00 44.55 ?  65  GLY   A CA  1 
ATOM   351  C C   . GLY   A 1 65  ? 202.699 173.212 166.674 1.00 44.55 ?  65  GLY   A C   1 
ATOM   352  O O   . GLY   A 1 65  ? 203.903 173.483 166.718 1.00 44.55 ?  65  GLY   A O   1 
ATOM   353  N N   . PRO   A 1 66  ? 202.153 172.309 167.488 1.00 42.27 ?  66  PRO   A N   1 
ATOM   354  C CA  . PRO   A 1 66  ? 203.005 171.566 168.425 1.00 42.27 ?  66  PRO   A CA  1 
ATOM   355  C C   . PRO   A 1 66  ? 204.095 170.771 167.744 1.00 42.27 ?  66  PRO   A C   1 
ATOM   356  O O   . PRO   A 1 66  ? 205.126 170.502 168.370 1.00 42.27 ?  66  PRO   A O   1 
ATOM   357  C CB  . PRO   A 1 66  ? 202.016 170.648 169.154 1.00 42.27 ?  66  PRO   A CB  1 
ATOM   358  C CG  . PRO   A 1 66  ? 200.778 170.650 168.325 1.00 42.27 ?  66  PRO   A CG  1 
ATOM   359  C CD  . PRO   A 1 66  ? 200.731 171.978 167.657 1.00 42.27 ?  66  PRO   A CD  1 
ATOM   360  N N   . ALA   A 1 67  ? 203.909 170.376 166.485 1.00 44.38 ?  67  ALA   A N   1 
ATOM   361  C CA  . ALA   A 1 67  ? 204.970 169.670 165.779 1.00 44.38 ?  67  ALA   A CA  1 
ATOM   362  C C   . ALA   A 1 67  ? 206.246 170.493 165.714 1.00 44.38 ?  67  ALA   A C   1 
ATOM   363  O O   . ALA   A 1 67  ? 207.337 169.922 165.609 1.00 44.38 ?  67  ALA   A O   1 
ATOM   364  C CB  . ALA   A 1 67  ? 204.515 169.300 164.367 1.00 44.38 ?  67  ALA   A CB  1 
ATOM   365  N N   . THR   A 1 68  ? 206.135 171.820 165.777 1.00 46.03 ?  68  THR   A N   1 
ATOM   366  C CA  . THR   A 1 68  ? 207.284 172.710 165.814 1.00 46.03 ?  68  THR   A CA  1 
ATOM   367  C C   . THR   A 1 68  ? 207.655 173.106 167.236 1.00 46.03 ?  68  THR   A C   1 
ATOM   368  O O   . THR   A 1 68  ? 208.538 173.947 167.430 1.00 46.03 ?  68  THR   A O   1 
ATOM   369  C CB  . THR   A 1 68  ? 207.010 173.960 164.978 1.00 46.03 ?  68  THR   A CB  1 
ATOM   370  O OG1 . THR   A 1 68  ? 206.046 174.782 165.647 1.00 46.03 ?  68  THR   A OG1 1 
ATOM   371  C CG2 . THR   A 1 68  ? 206.488 173.583 163.599 1.00 46.03 ?  68  THR   A CG2 1 
ATOM   372  N N   . LEU   A 1 69  ? 207.001 172.516 168.232 1.00 45.06 ?  69  LEU   A N   1 
ATOM   373  C CA  . LEU   A 1 69  ? 207.259 172.883 169.615 1.00 45.06 ?  69  LEU   A CA  1 
ATOM   374  C C   . LEU   A 1 69  ? 208.710 172.606 169.979 1.00 45.06 ?  69  LEU   A C   1 
ATOM   375  O O   . LEU   A 1 69  ? 209.317 171.642 169.504 1.00 45.06 ?  69  LEU   A O   1 
ATOM   376  C CB  . LEU   A 1 69  ? 206.327 172.109 170.547 1.00 45.06 ?  69  LEU   A CB  1 
ATOM   377  C CG  . LEU   A 1 69  ? 206.114 172.677 171.950 1.00 45.06 ?  69  LEU   A CG  1 
ATOM   378  C CD1 . LEU   A 1 69  ? 205.443 174.039 171.901 1.00 45.06 ?  69  LEU   A CD1 1 
ATOM   379  C CD2 . LEU   A 1 69  ? 205.296 171.707 172.789 1.00 45.06 ?  69  LEU   A CD2 1 
ATOM   380  N N   . GLY   A 1 70  ? 209.266 173.465 170.830 1.00 50.00 ?  70  GLY   A N   1 
ATOM   381  C CA  . GLY   A 1 70  ? 210.654 173.355 171.221 1.00 50.00 ?  70  GLY   A CA  1 
ATOM   382  C C   . GLY   A 1 70  ? 211.639 173.925 170.229 1.00 50.00 ?  70  GLY   A C   1 
ATOM   383  O O   . GLY   A 1 70  ? 212.834 173.624 170.325 1.00 50.00 ?  70  GLY   A O   1 
ATOM   384  N N   . HIS   A 1 71  ? 211.178 174.735 169.272 1.00 50.51 ?  71  HIS   A N   1 
ATOM   385  C CA  . HIS   A 1 71  ? 212.049 175.295 168.247 1.00 50.51 ?  71  HIS   A CA  1 
ATOM   386  C C   . HIS   A 1 71  ? 211.828 176.788 168.038 1.00 50.51 ?  71  HIS   A C   1 
ATOM   387  O O   . HIS   A 1 71  ? 212.347 177.347 167.065 1.00 50.51 ?  71  HIS   A O   1 
ATOM   388  C CB  . HIS   A 1 71  ? 211.857 174.545 166.927 1.00 50.51 ?  71  HIS   A CB  1 
ATOM   389  C CG  . HIS   A 1 71  ? 212.140 173.080 167.028 1.00 50.51 ?  71  HIS   A CG  1 
ATOM   390  N ND1 . HIS   A 1 71  ? 211.378 172.226 167.796 1.00 50.51 ?  71  HIS   A ND1 1 
ATOM   391  C CD2 . HIS   A 1 71  ? 213.110 172.318 166.469 1.00 50.51 ?  71  HIS   A CD2 1 
ATOM   392  C CE1 . HIS   A 1 71  ? 211.861 171.001 167.701 1.00 50.51 ?  71  HIS   A CE1 1 
ATOM   393  N NE2 . HIS   A 1 71  ? 212.912 171.029 166.902 1.00 50.51 ?  71  HIS   A NE2 1 
ATOM   394  N N   . GLY   A 1 72  ? 211.070 177.445 168.913 1.00 51.06 ?  72  GLY   A N   1 
ATOM   395  C CA  . GLY   A 1 72  ? 210.999 178.892 168.899 1.00 51.06 ?  72  GLY   A CA  1 
ATOM   396  C C   . GLY   A 1 72  ? 210.258 179.495 167.730 1.00 51.06 ?  72  GLY   A C   1 
ATOM   397  O O   . GLY   A 1 72  ? 210.386 180.698 167.486 1.00 51.06 ?  72  GLY   A O   1 
ATOM   398  N N   . ASN   A 1 73  ? 209.486 178.701 166.995 1.00 50.40 ?  73  ASN   A N   1 
ATOM   399  C CA  . ASN   A 1 73  ? 208.821 179.174 165.787 1.00 50.40 ?  73  ASN   A CA  1 
ATOM   400  C C   . ASN   A 1 73  ? 207.393 178.640 165.725 1.00 50.40 ?  73  ASN   A C   1 
ATOM   401  O O   . ASN   A 1 73  ? 206.933 178.154 164.692 1.00 50.40 ?  73  ASN   A O   1 
ATOM   402  C CB  . ASN   A 1 73  ? 209.616 178.762 164.549 1.00 50.40 ?  73  ASN   A CB  1 
ATOM   403  C CG  . ASN   A 1 73  ? 209.271 179.593 163.330 1.00 50.40 ?  73  ASN   A CG  1 
ATOM   404  O OD1 . ASN   A 1 73  ? 208.418 180.476 163.388 1.00 50.40 ?  73  ASN   A OD1 1 
ATOM   405  N ND2 . ASN   A 1 73  ? 209.938 179.314 162.216 1.00 50.40 ?  73  ASN   A ND2 1 
ATOM   406  N N   . LEU   A 1 74  ? 206.669 178.722 166.841 1.00 45.98 ?  74  LEU   A N   1 
ATOM   407  C CA  . LEU   A 1 74  ? 205.314 178.186 166.896 1.00 45.98 ?  74  LEU   A CA  1 
ATOM   408  C C   . LEU   A 1 74  ? 204.248 179.223 166.567 1.00 45.98 ?  74  LEU   A C   1 
ATOM   409  O O   . LEU   A 1 74  ? 203.284 178.897 165.871 1.00 45.98 ?  74  LEU   A O   1 
ATOM   410  C CB  . LEU   A 1 74  ? 205.031 177.582 168.274 1.00 45.98 ?  74  LEU   A CB  1 
ATOM   411  C CG  . LEU   A 1 74  ? 203.715 176.799 168.381 1.00 45.98 ?  74  LEU   A CG  1 
ATOM   412  C CD1 . LEU   A 1 74  ? 203.830 175.735 169.455 1.00 45.98 ?  74  LEU   A CD1 1 
ATOM   413  C CD2 . LEU   A 1 74  ? 202.528 177.699 168.674 1.00 45.98 ?  74  LEU   A CD2 1 
ATOM   414  N N   . TYR   A 1 75  ? 204.382 180.461 167.045 1.00 46.02 ?  75  TYR   A N   1 
ATOM   415  C CA  . TYR   A 1 75  ? 203.426 181.500 166.678 1.00 46.02 ?  75  TYR   A CA  1 
ATOM   416  C C   . TYR   A 1 75  ? 203.828 182.264 165.426 1.00 46.02 ?  75  TYR   A C   1 
ATOM   417  O O   . TYR   A 1 75  ? 202.953 182.815 164.749 1.00 46.02 ?  75  TYR   A O   1 
ATOM   418  C CB  . TYR   A 1 75  ? 203.227 182.490 167.831 1.00 46.02 ?  75  TYR   A CB  1 
ATOM   419  C CG  . TYR   A 1 75  ? 202.292 182.013 168.927 1.00 46.02 ?  75  TYR   A CG  1 
ATOM   420  C CD1 . TYR   A 1 75  ? 201.584 180.824 168.809 1.00 46.02 ?  75  TYR   A CD1 1 
ATOM   421  C CD2 . TYR   A 1 75  ? 202.095 182.773 170.068 1.00 46.02 ?  75  TYR   A CD2 1 
ATOM   422  C CE1 . TYR   A 1 75  ? 200.733 180.399 169.799 1.00 46.02 ?  75  TYR   A CE1 1 
ATOM   423  C CE2 . TYR   A 1 75  ? 201.242 182.354 171.064 1.00 46.02 ?  75  TYR   A CE2 1 
ATOM   424  C CZ  . TYR   A 1 75  ? 200.563 181.166 170.922 1.00 46.02 ?  75  TYR   A CZ  1 
ATOM   425  O OH  . TYR   A 1 75  ? 199.710 180.739 171.911 1.00 46.02 ?  75  TYR   A OH  1 
ATOM   426  N N   . GLU   A 1 76  ? 205.117 182.314 165.099 1.00 49.47 ?  76  GLU   A N   1 
ATOM   427  C CA  . GLU   A 1 76  ? 205.526 182.750 163.772 1.00 49.47 ?  76  GLU   A CA  1 
ATOM   428  C C   . GLU   A 1 76  ? 205.183 181.718 162.707 1.00 49.47 ?  76  GLU   A C   1 
ATOM   429  O O   . GLU   A 1 76  ? 205.327 182.006 161.515 1.00 49.47 ?  76  GLU   A O   1 
ATOM   430  C CB  . GLU   A 1 76  ? 207.029 183.043 163.745 1.00 49.47 ?  76  GLU   A CB  1 
ATOM   431  C CG  . GLU   A 1 76  ? 207.396 184.486 164.089 1.00 49.47 ?  76  GLU   A CG  1 
ATOM   432  C CD  . GLU   A 1 76  ? 207.754 184.685 165.553 1.00 49.47 ?  76  GLU   A CD  1 
ATOM   433  O OE1 . GLU   A 1 76  ? 207.895 183.684 166.286 1.00 49.47 ?  76  GLU   A OE1 1 
ATOM   434  O OE2 . GLU   A 1 76  ? 207.896 185.853 165.972 1.00 49.47 -1 76  GLU   A OE2 1 
ATOM   435  N N   . PHE   A 1 77  ? 204.742 180.531 163.117 1.00 47.63 ?  77  PHE   A N   1 
ATOM   436  C CA  . PHE   A 1 77  ? 204.333 179.501 162.174 1.00 47.63 ?  77  PHE   A CA  1 
ATOM   437  C C   . PHE   A 1 77  ? 203.180 179.971 161.300 1.00 47.63 ?  77  PHE   A C   1 
ATOM   438  O O   . PHE   A 1 77  ? 202.256 180.645 161.763 1.00 47.63 ?  77  PHE   A O   1 
ATOM   439  C CB  . PHE   A 1 77  ? 203.920 178.238 162.929 1.00 47.63 ?  77  PHE   A CB  1 
ATOM   440  C CG  . PHE   A 1 77  ? 203.511 177.109 162.036 1.00 47.63 ?  77  PHE   A CG  1 
ATOM   441  C CD1 . PHE   A 1 77  ? 204.457 176.369 161.349 1.00 47.63 ?  77  PHE   A CD1 1 
ATOM   442  C CD2 . PHE   A 1 77  ? 202.175 176.784 161.885 1.00 47.63 ?  77  PHE   A CD2 1 
ATOM   443  C CE1 . PHE   A 1 77  ? 204.076 175.329 160.524 1.00 47.63 ?  77  PHE   A CE1 1 
ATOM   444  C CE2 . PHE   A 1 77  ? 201.789 175.746 161.064 1.00 47.63 ?  77  PHE   A CE2 1 
ATOM   445  C CZ  . PHE   A 1 77  ? 202.740 175.017 160.383 1.00 47.63 ?  77  PHE   A CZ  1 
ATOM   446  N N   . THR   A 1 78  ? 203.245 179.604 160.023 1.00 47.28 ?  78  THR   A N   1 
ATOM   447  C CA  . THR   A 1 78  ? 202.152 179.786 159.082 1.00 47.28 ?  78  THR   A CA  1 
ATOM   448  C C   . THR   A 1 78  ? 201.942 178.478 158.336 1.00 47.28 ?  78  THR   A C   1 
ATOM   449  O O   . THR   A 1 78  ? 202.878 177.694 158.158 1.00 47.28 ?  78  THR   A O   1 
ATOM   450  C CB  . THR   A 1 78  ? 202.435 180.916 158.087 1.00 47.28 ?  78  THR   A CB  1 
ATOM   451  O OG1 . THR   A 1 78  ? 203.770 180.792 157.584 1.00 47.28 ?  78  THR   A OG1 1 
ATOM   452  C CG2 . THR   A 1 78  ? 202.274 182.269 158.760 1.00 47.28 ?  78  THR   A CG2 1 
ATOM   453  N N   . TYR   A 1 79  ? 200.706 178.245 157.904 1.00 46.23 ?  79  TYR   A N   1 
ATOM   454  C CA  . TYR   A 1 79  ? 200.326 176.999 157.239 1.00 46.23 ?  79  TYR   A CA  1 
ATOM   455  C C   . TYR   A 1 79  ? 199.612 177.305 155.929 1.00 46.23 ?  79  TYR   A C   1 
ATOM   456  O O   . TYR   A 1 79  ? 198.393 177.152 155.814 1.00 46.23 ?  79  TYR   A O   1 
ATOM   457  C CB  . TYR   A 1 79  ? 199.448 176.151 158.157 1.00 46.23 ?  79  TYR   A CB  1 
ATOM   458  C CG  . TYR   A 1 79  ? 199.129 174.783 157.602 1.00 46.23 ?  79  TYR   A CG  1 
ATOM   459  C CD1 . TYR   A 1 79  ? 200.141 173.898 157.260 1.00 46.23 ?  79  TYR   A CD1 1 
ATOM   460  C CD2 . TYR   A 1 79  ? 197.816 174.376 157.424 1.00 46.23 ?  79  TYR   A CD2 1 
ATOM   461  C CE1 . TYR   A 1 79  ? 199.853 172.650 156.754 1.00 46.23 ?  79  TYR   A CE1 1 
ATOM   462  C CE2 . TYR   A 1 79  ? 197.519 173.130 156.920 1.00 46.23 ?  79  TYR   A CE2 1 
ATOM   463  C CZ  . TYR   A 1 79  ? 198.540 172.270 156.586 1.00 46.23 ?  79  TYR   A CZ  1 
ATOM   464  O OH  . TYR   A 1 79  ? 198.246 171.025 156.083 1.00 46.23 ?  79  TYR   A OH  1 
ATOM   465  N N   . PRO   A 1 80  ? 200.350 177.751 154.912 1.00 48.24 ?  80  PRO   A N   1 
ATOM   466  C CA  . PRO   A 1 80  ? 199.744 178.032 153.607 1.00 48.24 ?  80  PRO   A CA  1 
ATOM   467  C C   . PRO   A 1 80  ? 199.638 176.828 152.684 1.00 48.24 ?  80  PRO   A C   1 
ATOM   468  O O   . PRO   A 1 80  ? 199.263 176.998 151.521 1.00 48.24 ?  80  PRO   A O   1 
ATOM   469  C CB  . PRO   A 1 80  ? 200.703 179.078 153.022 1.00 48.24 ?  80  PRO   A CB  1 
ATOM   470  C CG  . PRO   A 1 80  ? 202.028 178.695 153.575 1.00 48.24 ?  80  PRO   A CG  1 
ATOM   471  C CD  . PRO   A 1 80  ? 201.769 178.142 154.955 1.00 48.24 ?  80  PRO   A CD  1 
ATOM   472  N N   . ASP   A 1 81  ? 199.955 175.624 153.161 1.00 47.66 ?  81  ASP   A N   1 
ATOM   473  C CA  . ASP   A 1 81  ? 199.928 174.456 152.288 1.00 47.66 ?  81  ASP   A CA  1 
ATOM   474  C C   . ASP   A 1 81  ? 198.526 174.211 151.743 1.00 47.66 ?  81  ASP   A C   1 
ATOM   475  O O   . ASP   A 1 81  ? 198.352 173.908 150.558 1.00 47.66 ?  81  ASP   A O   1 
ATOM   476  C CB  . ASP   A 1 81  ? 200.432 173.228 153.046 1.00 47.66 ?  81  ASP   A CB  1 
ATOM   477  C CG  . ASP   A 1 81  ? 201.893 173.340 153.429 1.00 47.66 ?  81  ASP   A CG  1 
ATOM   478  O OD1 . ASP   A 1 81  ? 202.577 174.246 152.908 1.00 47.66 ?  81  ASP   A OD1 1 
ATOM   479  O OD2 . ASP   A 1 81  ? 202.357 172.522 154.251 1.00 47.66 -1 81  ASP   A OD2 1 
ATOM   480  N N   . LYS   A 1 82  ? 197.513 174.337 152.595 1.00 45.75 ?  82  LYS   A N   1 
ATOM   481  C CA  . LYS   A 1 82  ? 196.140 174.035 152.218 1.00 45.75 ?  82  LYS   A CA  1 
ATOM   482  C C   . LYS   A 1 82  ? 195.394 175.235 151.649 1.00 45.75 ?  82  LYS   A C   1 
ATOM   483  O O   . LYS   A 1 82  ? 194.444 175.045 150.883 1.00 45.75 ?  82  LYS   A O   1 
ATOM   484  C CB  . LYS   A 1 82  ? 195.380 173.489 153.432 1.00 45.75 ?  82  LYS   A CB  1 
ATOM   485  C CG  . LYS   A 1 82  ? 195.871 172.135 153.945 1.00 45.75 ?  82  LYS   A CG  1 
ATOM   486  C CD  . LYS   A 1 82  ? 196.300 171.194 152.823 1.00 45.75 ?  82  LYS   A CD  1 
ATOM   487  C CE  . LYS   A 1 82  ? 196.470 169.766 153.318 1.00 45.75 ?  82  LYS   A CE  1 
ATOM   488  N NZ  . LYS   A 1 82  ? 195.191 169.184 153.810 1.00 45.75 1  82  LYS   A NZ  1 
ATOM   489  N N   . THR   A 1 83  ? 195.790 176.459 152.002 1.00 47.55 ?  83  THR   A N   1 
ATOM   490  C CA  . THR   A 1 83  ? 195.181 177.669 151.446 1.00 47.55 ?  83  THR   A CA  1 
ATOM   491  C C   . THR   A 1 83  ? 196.289 178.647 151.086 1.00 47.55 ?  83  THR   A C   1 
ATOM   492  O O   . THR   A 1 83  ? 196.489 179.665 151.757 1.00 47.55 ?  83  THR   A O   1 
ATOM   493  C CB  . THR   A 1 83  ? 194.198 178.293 152.435 1.00 47.55 ?  83  THR   A CB  1 
ATOM   494  O OG1 . THR   A 1 83  ? 194.913 178.807 153.564 1.00 47.55 ?  83  THR   A OG1 1 
ATOM   495  C CG2 . THR   A 1 83  ? 193.186 177.261 152.908 1.00 47.55 ?  83  THR   A CG2 1 
ATOM   496  N N   . PRO   A 1 84  ? 197.050 178.353 150.024 1.00 49.62 ?  84  PRO   A N   1 
ATOM   497  C CA  . PRO   A 1 84  ? 198.154 179.235 149.624 1.00 49.62 ?  84  PRO   A CA  1 
ATOM   498  C C   . PRO   A 1 84  ? 197.819 180.714 149.723 1.00 49.62 ?  84  PRO   A C   1 
ATOM   499  O O   . PRO   A 1 84  ? 198.656 181.518 150.143 1.00 49.62 ?  84  PRO   A O   1 
ATOM   500  C CB  . PRO   A 1 84  ? 198.411 178.823 148.169 1.00 49.62 ?  84  PRO   A CB  1 
ATOM   501  C CG  . PRO   A 1 84  ? 197.862 177.411 148.041 1.00 49.62 ?  84  PRO   A CG  1 
ATOM   502  C CD  . PRO   A 1 84  ? 197.083 177.078 149.290 1.00 49.62 ?  84  PRO   A CD  1 
ATOM   503  N N   . ASP   A 1 85  ? 196.597 181.085 149.338 1.00 49.84 ?  85  ASP   A N   1 
ATOM   504  C CA  . ASP   A 1 85  ? 196.188 182.483 149.403 1.00 49.84 ?  85  ASP   A CA  1 
ATOM   505  C C   . ASP   A 1 85  ? 196.308 183.022 150.824 1.00 49.84 ?  85  ASP   A C   1 
ATOM   506  O O   . ASP   A 1 85  ? 196.951 184.049 151.064 1.00 49.84 ?  85  ASP   A O   1 
ATOM   507  C CB  . ASP   A 1 85  ? 194.753 182.630 148.893 1.00 49.84 ?  85  ASP   A CB  1 
ATOM   508  C CG  . ASP   A 1 85  ? 194.589 182.153 147.464 1.00 49.84 ?  85  ASP   A CG  1 
ATOM   509  O OD1 . ASP   A 1 85  ? 195.494 182.408 146.642 1.00 49.84 ?  85  ASP   A OD1 1 
ATOM   510  O OD2 . ASP   A 1 85  ? 193.553 181.523 147.161 1.00 49.84 -1 85  ASP   A OD2 1 
ATOM   511  N N   . PHE   A 1 86  ? 195.691 182.330 151.784 1.00 47.86 ?  86  PHE   A N   1 
ATOM   512  C CA  . PHE   A 1 86  ? 195.713 182.756 153.175 1.00 47.86 ?  86  PHE   A CA  1 
ATOM   513  C C   . PHE   A 1 86  ? 196.520 181.763 153.997 1.00 47.86 ?  86  PHE   A C   1 
ATOM   514  O O   . PHE   A 1 86  ? 196.043 180.643 154.233 1.00 47.86 ?  86  PHE   A O   1 
ATOM   515  C CB  . PHE   A 1 86  ? 194.293 182.868 153.725 1.00 47.86 ?  86  PHE   A CB  1 
ATOM   516  C CG  . PHE   A 1 86  ? 194.234 183.101 155.207 1.00 47.86 ?  86  PHE   A CG  1 
ATOM   517  C CD1 . PHE   A 1 86  ? 194.708 184.280 155.756 1.00 47.86 ?  86  PHE   A CD1 1 
ATOM   518  C CD2 . PHE   A 1 86  ? 193.699 182.144 156.052 1.00 47.86 ?  86  PHE   A CD2 1 
ATOM   519  C CE1 . PHE   A 1 86  ? 194.655 184.497 157.120 1.00 47.86 ?  86  PHE   A CE1 1 
ATOM   520  C CE2 . PHE   A 1 86  ? 193.643 182.356 157.416 1.00 47.86 ?  86  PHE   A CE2 1 
ATOM   521  C CZ  . PHE   A 1 86  ? 194.121 183.534 157.950 1.00 47.86 ?  86  PHE   A CZ  1 
ATOM   522  N N   . PRO   A 1 87  ? 197.728 182.106 154.451 1.00 48.27 ?  87  PRO   A N   1 
ATOM   523  C CA  . PRO   A 1 87  ? 198.470 181.181 155.318 1.00 48.27 ?  87  PRO   A CA  1 
ATOM   524  C C   . PRO   A 1 87  ? 197.817 181.031 156.681 1.00 48.27 ?  87  PRO   A C   1 
ATOM   525  O O   . PRO   A 1 87  ? 197.697 182.006 157.428 1.00 48.27 ?  87  PRO   A O   1 
ATOM   526  C CB  . PRO   A 1 87  ? 199.860 181.825 155.427 1.00 48.27 ?  87  PRO   A CB  1 
ATOM   527  C CG  . PRO   A 1 87  ? 199.909 182.876 154.365 1.00 48.27 ?  87  PRO   A CG  1 
ATOM   528  C CD  . PRO   A 1 87  ? 198.505 183.319 154.152 1.00 48.27 ?  87  PRO   A CD  1 
ATOM   529  N N   . LEU   A 1 88  ? 197.395 179.821 157.014 1.00 46.08 ?  88  LEU   A N   1 
ATOM   530  C CA  . LEU   A 1 88  ? 196.741 179.570 158.291 1.00 46.08 ?  88  LEU   A CA  1 
ATOM   531  C C   . LEU   A 1 88  ? 197.750 179.699 159.425 1.00 46.08 ?  88  LEU   A C   1 
ATOM   532  O O   . LEU   A 1 88  ? 198.735 178.950 159.442 1.00 46.08 ?  88  LEU   A O   1 
ATOM   533  C CB  . LEU   A 1 88  ? 196.121 178.173 158.301 1.00 46.08 ?  88  LEU   A CB  1 
ATOM   534  C CG  . LEU   A 1 88  ? 194.661 178.036 157.867 1.00 46.08 ?  88  LEU   A CG  1 
ATOM   535  C CD1 . LEU   A 1 88  ? 193.731 178.754 158.832 1.00 46.08 ?  88  LEU   A CD1 1 
ATOM   536  C CD2 . LEU   A 1 88  ? 194.476 178.551 156.456 1.00 46.08 ?  88  LEU   A CD2 1 
ATOM   537  N N   . PRO   A 1 89  ? 197.561 180.612 160.378 1.00 45.81 ?  89  PRO   A N   1 
ATOM   538  C CA  . PRO   A 1 89  ? 198.477 180.673 161.521 1.00 45.81 ?  89  PRO   A CA  1 
ATOM   539  C C   . PRO   A 1 89  ? 197.990 179.831 162.687 1.00 45.81 ?  89  PRO   A C   1 
ATOM   540  O O   . PRO   A 1 89  ? 196.917 179.224 162.615 1.00 45.81 ?  89  PRO   A O   1 
ATOM   541  C CB  . PRO   A 1 89  ? 198.486 182.164 161.864 1.00 45.81 ?  89  PRO   A CB  1 
ATOM   542  C CG  . PRO   A 1 89  ? 197.092 182.603 161.544 1.00 45.81 ?  89  PRO   A CG  1 
ATOM   543  C CD  . PRO   A 1 89  ? 196.598 181.727 160.404 1.00 45.81 ?  89  PRO   A CD  1 
ATOM   544  N N   . PHE   A 1 90  ? 198.773 179.781 163.765 1.00 43.25 ?  90  PHE   A N   1 
ATOM   545  C CA  . PHE   A 1 90  ? 198.352 179.133 165.006 1.00 43.25 ?  90  PHE   A CA  1 
ATOM   546  C C   . PHE   A 1 90  ? 198.021 180.230 166.011 1.00 43.25 ?  90  PHE   A C   1 
ATOM   547  O O   . PHE   A 1 90  ? 198.859 180.673 166.795 1.00 43.25 ?  90  PHE   A O   1 
ATOM   548  C CB  . PHE   A 1 90  ? 199.431 178.192 165.525 1.00 43.25 ?  90  PHE   A CB  1 
ATOM   549  C CG  . PHE   A 1 90  ? 198.965 177.299 166.637 1.00 43.25 ?  90  PHE   A CG  1 
ATOM   550  C CD1 . PHE   A 1 90  ? 198.922 177.759 167.939 1.00 43.25 ?  90  PHE   A CD1 1 
ATOM   551  C CD2 . PHE   A 1 90  ? 198.556 176.005 166.379 1.00 43.25 ?  90  PHE   A CD2 1 
ATOM   552  C CE1 . PHE   A 1 90  ? 198.492 176.943 168.960 1.00 43.25 ?  90  PHE   A CE1 1 
ATOM   553  C CE2 . PHE   A 1 90  ? 198.123 175.186 167.398 1.00 43.25 ?  90  PHE   A CE2 1 
ATOM   554  C CZ  . PHE   A 1 90  ? 198.090 175.656 168.688 1.00 43.25 ?  90  PHE   A CZ  1 
ATOM   555  N N   . THR   A 1 91  ? 196.766 180.670 165.978 1.00 44.17 ?  91  THR   A N   1 
ATOM   556  C CA  . THR   A 1 91  ? 196.302 181.743 166.847 1.00 44.17 ?  91  THR   A CA  1 
ATOM   557  C C   . THR   A 1 91  ? 195.759 181.239 168.178 1.00 44.17 ?  91  THR   A C   1 
ATOM   558  O O   . THR   A 1 91  ? 195.315 182.053 168.994 1.00 44.17 ?  91  THR   A O   1 
ATOM   559  C CB  . THR   A 1 91  ? 195.224 182.565 166.134 1.00 44.17 ?  91  THR   A CB  1 
ATOM   560  O OG1 . THR   A 1 91  ? 194.889 183.710 166.927 1.00 44.17 ?  91  THR   A OG1 1 
ATOM   561  C CG2 . THR   A 1 91  ? 193.971 181.729 165.898 1.00 44.17 ?  91  THR   A CG2 1 
ATOM   562  N N   . TYR   A 1 92  ? 195.785 179.934 168.418 1.00 41.87 ?  92  TYR   A N   1 
ATOM   563  C CA  . TYR   A 1 92  ? 195.230 179.395 169.645 1.00 41.87 ?  92  TYR   A CA  1 
ATOM   564  C C   . TYR   A 1 92  ? 196.112 179.757 170.839 1.00 41.87 ?  92  TYR   A C   1 
ATOM   565  O O   . TYR   A 1 92  ? 197.296 180.062 170.677 1.00 41.87 ?  92  TYR   A O   1 
ATOM   566  C CB  . TYR   A 1 92  ? 195.104 177.882 169.555 1.00 41.87 ?  92  TYR   A CB  1 
ATOM   567  C CG  . TYR   A 1 92  ? 193.786 177.406 169.013 1.00 41.87 ?  92  TYR   A CG  1 
ATOM   568  C CD1 . TYR   A 1 92  ? 193.274 177.919 167.834 1.00 41.87 ?  92  TYR   A CD1 1 
ATOM   569  C CD2 . TYR   A 1 92  ? 193.050 176.443 169.683 1.00 41.87 ?  92  TYR   A CD2 1 
ATOM   570  C CE1 . TYR   A 1 92  ? 192.071 177.483 167.337 1.00 41.87 ?  92  TYR   A CE1 1 
ATOM   571  C CE2 . TYR   A 1 92  ? 191.847 176.004 169.194 1.00 41.87 ?  92  TYR   A CE2 1 
ATOM   572  C CZ  . TYR   A 1 92  ? 191.360 176.529 168.024 1.00 41.87 ?  92  TYR   A CZ  1 
ATOM   573  O OH  . TYR   A 1 92  ? 190.157 176.088 167.528 1.00 41.87 ?  92  TYR   A OH  1 
ATOM   574  N N   . PRO   A 1 93  ? 195.558 179.735 172.048 1.00 42.83 ?  93  PRO   A N   1 
ATOM   575  C CA  . PRO   A 1 93  ? 196.379 179.939 173.243 1.00 42.83 ?  93  PRO   A CA  1 
ATOM   576  C C   . PRO   A 1 93  ? 197.439 178.860 173.363 1.00 42.83 ?  93  PRO   A C   1 
ATOM   577  O O   . PRO   A 1 93  ? 197.252 177.739 172.869 1.00 42.83 ?  93  PRO   A O   1 
ATOM   578  C CB  . PRO   A 1 93  ? 195.366 179.848 174.392 1.00 42.83 ?  93  PRO   A CB  1 
ATOM   579  C CG  . PRO   A 1 93  ? 194.062 180.193 173.794 1.00 42.83 ?  93  PRO   A CG  1 
ATOM   580  C CD  . PRO   A 1 93  ? 194.119 179.872 172.329 1.00 42.83 ?  93  PRO   A CD  1 
ATOM   581  N N   . PRO   A 1 94  ? 198.569 179.154 174.010 1.00 42.53 ?  94  PRO   A N   1 
ATOM   582  C CA  . PRO   A 1 94  ? 199.627 178.138 174.117 1.00 42.53 ?  94  PRO   A CA  1 
ATOM   583  C C   . PRO   A 1 94  ? 199.176 176.871 174.822 1.00 42.53 ?  94  PRO   A C   1 
ATOM   584  O O   . PRO   A 1 94  ? 199.706 175.788 174.540 1.00 42.53 ?  94  PRO   A O   1 
ATOM   585  C CB  . PRO   A 1 94  ? 200.730 178.861 174.902 1.00 42.53 ?  94  PRO   A CB  1 
ATOM   586  C CG  . PRO   A 1 94  ? 200.400 180.307 174.821 1.00 42.53 ?  94  PRO   A CG  1 
ATOM   587  C CD  . PRO   A 1 94  ? 198.919 180.383 174.738 1.00 42.53 ?  94  PRO   A CD  1 
ATOM   588  N N   . PHE   A 1 95  ? 198.216 176.973 175.743 1.00 41.16 ?  95  PHE   A N   1 
ATOM   589  C CA  . PHE   A 1 95  ? 197.674 175.774 176.371 1.00 41.16 ?  95  PHE   A CA  1 
ATOM   590  C C   . PHE   A 1 95  ? 197.088 174.827 175.334 1.00 41.16 ?  95  PHE   A C   1 
ATOM   591  O O   . PHE   A 1 95  ? 197.152 173.603 175.501 1.00 41.16 ?  95  PHE   A O   1 
ATOM   592  C CB  . PHE   A 1 95  ? 196.614 176.162 177.401 1.00 41.16 ?  95  PHE   A CB  1 
ATOM   593  C CG  . PHE   A 1 95  ? 196.023 174.994 178.130 1.00 41.16 ?  95  PHE   A CG  1 
ATOM   594  C CD1 . PHE   A 1 95  ? 196.733 174.352 179.127 1.00 41.16 ?  95  PHE   A CD1 1 
ATOM   595  C CD2 . PHE   A 1 95  ? 194.752 174.544 177.824 1.00 41.16 ?  95  PHE   A CD2 1 
ATOM   596  C CE1 . PHE   A 1 95  ? 196.191 173.278 179.797 1.00 41.16 ?  95  PHE   A CE1 1 
ATOM   597  C CE2 . PHE   A 1 95  ? 194.204 173.473 178.492 1.00 41.16 ?  95  PHE   A CE2 1 
ATOM   598  C CZ  . PHE   A 1 95  ? 194.923 172.839 179.480 1.00 41.16 ?  95  PHE   A CZ  1 
ATOM   599  N N   . ALA   A 1 96  ? 196.520 175.368 174.257 1.00 41.81 ?  96  ALA   A N   1 
ATOM   600  C CA  . ALA   A 1 96  ? 196.030 174.517 173.182 1.00 41.81 ?  96  ALA   A CA  1 
ATOM   601  C C   . ALA   A 1 96  ? 197.170 173.745 172.536 1.00 41.81 ?  96  ALA   A C   1 
ATOM   602  O O   . ALA   A 1 96  ? 197.022 172.562 172.216 1.00 41.81 ?  96  ALA   A O   1 
ATOM   603  C CB  . ALA   A 1 96  ? 195.297 175.355 172.139 1.00 41.81 ?  96  ALA   A CB  1 
ATOM   604  N N   . ALA   A 1 97  ? 198.315 174.396 172.327 1.00 42.00 ?  97  ALA   A N   1 
ATOM   605  C CA  . ALA   A 1 97  ? 199.466 173.688 171.780 1.00 42.00 ?  97  ALA   A CA  1 
ATOM   606  C C   . ALA   A 1 97  ? 199.954 172.614 172.741 1.00 42.00 ?  97  ALA   A C   1 
ATOM   607  O O   . ALA   A 1 97  ? 200.359 171.525 172.317 1.00 42.00 ?  97  ALA   A O   1 
ATOM   608  C CB  . ALA   A 1 97  ? 200.587 174.673 171.462 1.00 42.00 ?  97  ALA   A CB  1 
ATOM   609  N N   . VAL   A 1 98  ? 199.917 172.898 174.042 1.00 42.03 ?  98  VAL   A N   1 
ATOM   610  C CA  . VAL   A 1 98  ? 200.288 171.879 175.019 1.00 42.03 ?  98  VAL   A CA  1 
ATOM   611  C C   . VAL   A 1 98  ? 199.361 170.678 174.903 1.00 42.03 ?  98  VAL   A C   1 
ATOM   612  O O   . VAL   A 1 98  ? 199.806 169.524 174.911 1.00 42.03 ?  98  VAL   A O   1 
ATOM   613  C CB  . VAL   A 1 98  ? 200.262 172.469 176.440 1.00 42.03 ?  98  VAL   A CB  1 
ATOM   614  C CG1 . VAL   A 1 98  ? 200.547 171.388 177.470 1.00 42.03 ?  98  VAL   A CG1 1 
ATOM   615  C CG2 . VAL   A 1 98  ? 201.248 173.613 176.552 1.00 42.03 ?  98  VAL   A CG2 1 
ATOM   616  N N   . VAL   A 1 99  ? 198.056 170.930 174.794 1.00 41.76 ?  99  VAL   A N   1 
ATOM   617  C CA  . VAL   A 1 99  ? 197.084 169.842 174.738 1.00 41.76 ?  99  VAL   A CA  1 
ATOM   618  C C   . VAL   A 1 99  ? 197.202 169.074 173.427 1.00 41.76 ?  99  VAL   A C   1 
ATOM   619  O O   . VAL   A 1 99  ? 196.903 167.877 173.369 1.00 41.76 ?  99  VAL   A O   1 
ATOM   620  C CB  . VAL   A 1 99  ? 195.660 170.391 174.938 1.00 41.76 ?  99  VAL   A CB  1 
ATOM   621  C CG1 . VAL   A 1 99  ? 194.629 169.316 174.628 1.00 41.76 ?  99  VAL   A CG1 1 
ATOM   622  C CG2 . VAL   A 1 99  ? 195.487 170.910 176.356 1.00 41.76 ?  99  VAL   A CG2 1 
ATOM   623  N N   . PHE   A 1 100 ? 197.603 169.749 172.353 1.00 41.27 ?  100 PHE   A N   1 
ATOM   624  C CA  . PHE   A 1 100 ? 197.694 169.132 171.037 1.00 41.27 ?  100 PHE   A CA  1 
ATOM   625  C C   . PHE   A 1 100 ? 199.061 168.530 170.746 1.00 41.27 ?  100 PHE   A C   1 
ATOM   626  O O   . PHE   A 1 100 ? 199.237 167.927 169.684 1.00 41.27 ?  100 PHE   A O   1 
ATOM   627  C CB  . PHE   A 1 100 ? 197.363 170.158 169.949 1.00 41.27 ?  100 PHE   A CB  1 
ATOM   628  C CG  . PHE   A 1 100 ? 195.964 170.700 170.022 1.00 41.27 ?  100 PHE   A CG  1 
ATOM   629  C CD1 . PHE   A 1 100 ? 194.930 169.942 170.537 1.00 41.27 ?  100 PHE   A CD1 1 
ATOM   630  C CD2 . PHE   A 1 100 ? 195.685 171.977 169.567 1.00 41.27 ?  100 PHE   A CD2 1 
ATOM   631  C CE1 . PHE   A 1 100 ? 193.646 170.448 170.597 1.00 41.27 ?  100 PHE   A CE1 1 
ATOM   632  C CE2 . PHE   A 1 100 ? 194.406 172.485 169.626 1.00 41.27 ?  100 PHE   A CE2 1 
ATOM   633  C CZ  . PHE   A 1 100 ? 193.386 171.721 170.141 1.00 41.27 ?  100 PHE   A CZ  1 
ATOM   634  N N   . TRP   A 1 101 ? 200.041 168.700 171.629 1.00 41.67 ?  101 TRP   A N   1 
ATOM   635  C CA  . TRP   A 1 101 ? 201.313 168.016 171.416 1.00 41.67 ?  101 TRP   A CA  1 
ATOM   636  C C   . TRP   A 1 101 ? 201.155 166.506 171.299 1.00 41.67 ?  101 TRP   A C   1 
ATOM   637  O O   . TRP   A 1 101 ? 201.869 165.903 170.481 1.00 41.67 ?  101 TRP   A O   1 
ATOM   638  C CB  . TRP   A 1 101 ? 202.306 168.365 172.528 1.00 41.67 ?  101 TRP   A CB  1 
ATOM   639  C CG  . TRP   A 1 101 ? 203.696 167.945 172.188 1.00 41.67 ?  101 TRP   A CG  1 
ATOM   640  C CD1 . TRP   A 1 101 ? 204.587 168.620 171.411 1.00 41.67 ?  101 TRP   A CD1 1 
ATOM   641  C CD2 . TRP   A 1 101 ? 204.350 166.741 172.596 1.00 41.67 ?  101 TRP   A CD2 1 
ATOM   642  N NE1 . TRP   A 1 101 ? 205.760 167.915 171.315 1.00 41.67 ?  101 TRP   A NE1 1 
ATOM   643  C CE2 . TRP   A 1 101 ? 205.640 166.757 172.035 1.00 41.67 ?  101 TRP   A CE2 1 
ATOM   644  C CE3 . TRP   A 1 101 ? 203.973 165.654 173.387 1.00 41.67 ?  101 TRP   A CE3 1 
ATOM   645  C CZ2 . TRP   A 1 101 ? 206.554 165.729 172.239 1.00 41.67 ?  101 TRP   A CZ2 1 
ATOM   646  C CZ3 . TRP   A 1 101 ? 204.882 164.635 173.589 1.00 41.67 ?  101 TRP   A CZ3 1 
ATOM   647  C CH2 . TRP   A 1 101 ? 206.157 164.679 173.017 1.00 41.67 ?  101 TRP   A CH2 1 
ATOM   648  N N   . PRO   A 1 102 ? 200.297 165.839 172.070 1.00 40.84 ?  102 PRO   A N   1 
ATOM   649  C CA  . PRO   A 1 102 ? 200.060 164.411 171.815 1.00 40.84 ?  102 PRO   A CA  1 
ATOM   650  C C   . PRO   A 1 102 ? 199.618 164.114 170.391 1.00 40.84 ?  102 PRO   A C   1 
ATOM   651  O O   . PRO   A 1 102 ? 200.017 163.085 169.832 1.00 40.84 ?  102 PRO   A O   1 
ATOM   652  C CB  . PRO   A 1 102 ? 198.968 164.056 172.832 1.00 40.84 ?  102 PRO   A CB  1 
ATOM   653  C CG  . PRO   A 1 102 ? 199.164 165.018 173.937 1.00 40.84 ?  102 PRO   A CG  1 
ATOM   654  C CD  . PRO   A 1 102 ? 199.648 166.292 173.310 1.00 40.84 ?  102 PRO   A CD  1 
ATOM   655  N N   . LEU   A 1 103 ? 198.807 164.984 169.781 1.00 40.73 ?  103 LEU   A N   1 
ATOM   656  C CA  . LEU   A 1 103 ? 198.389 164.763 168.400 1.00 40.73 ?  103 LEU   A CA  1 
ATOM   657  C C   . LEU   A 1 103 ? 199.589 164.611 167.477 1.00 40.73 ?  103 LEU   A C   1 
ATOM   658  O O   . LEU   A 1 103 ? 199.508 163.915 166.460 1.00 40.73 ?  103 LEU   A O   1 
ATOM   659  C CB  . LEU   A 1 103 ? 197.507 165.917 167.932 1.00 40.73 ?  103 LEU   A CB  1 
ATOM   660  C CG  . LEU   A 1 103 ? 196.009 165.743 168.163 1.00 40.73 ?  103 LEU   A CG  1 
ATOM   661  C CD1 . LEU   A 1 103 ? 195.715 165.608 169.646 1.00 40.73 ?  103 LEU   A CD1 1 
ATOM   662  C CD2 . LEU   A 1 103 ? 195.246 166.917 167.571 1.00 40.73 ?  103 LEU   A CD2 1 
ATOM   663  N N   . HIS   A 1 104 ? 200.709 165.247 167.821 1.00 42.39 ?  104 HIS   A N   1 
ATOM   664  C CA  . HIS   A 1 104 ? 201.933 165.089 167.043 1.00 42.39 ?  104 HIS   A CA  1 
ATOM   665  C C   . HIS   A 1 104 ? 202.383 163.636 166.979 1.00 42.39 ?  104 HIS   A C   1 
ATOM   666  O O   . HIS   A 1 104 ? 203.134 163.261 166.073 1.00 42.39 ?  104 HIS   A O   1 
ATOM   667  C CB  . HIS   A 1 104 ? 203.032 165.955 167.653 1.00 42.39 ?  104 HIS   A CB  1 
ATOM   668  C CG  . HIS   A 1 104 ? 204.331 165.897 166.918 1.00 42.39 ?  104 HIS   A CG  1 
ATOM   669  N ND1 . HIS   A 1 104 ? 204.531 166.516 165.704 1.00 42.39 ?  104 HIS   A ND1 1 
ATOM   670  C CD2 . HIS   A 1 104 ? 205.505 165.301 167.236 1.00 42.39 ?  104 HIS   A CD2 1 
ATOM   671  C CE1 . HIS   A 1 104 ? 205.770 166.298 165.301 1.00 42.39 ?  104 HIS   A CE1 1 
ATOM   672  N NE2 . HIS   A 1 104 ? 206.382 165.563 166.212 1.00 42.39 ?  104 HIS   A NE2 1 
ATOM   673  N N   . LEU   A 1 105 ? 201.945 162.807 167.925 1.00 43.24 ?  105 LEU   A N   1 
ATOM   674  C CA  . LEU   A 1 105 ? 202.377 161.418 167.979 1.00 43.24 ?  105 LEU   A CA  1 
ATOM   675  C C   . LEU   A 1 105 ? 201.467 160.474 167.201 1.00 43.24 ?  105 LEU   A C   1 
ATOM   676  O O   . LEU   A 1 105 ? 201.695 159.260 167.241 1.00 43.24 ?  105 LEU   A O   1 
ATOM   677  C CB  . LEU   A 1 105 ? 202.456 160.951 169.435 1.00 43.24 ?  105 LEU   A CB  1 
ATOM   678  C CG  . LEU   A 1 105 ? 203.652 161.448 170.251 1.00 43.24 ?  105 LEU   A CG  1 
ATOM   679  C CD1 . LEU   A 1 105 ? 203.332 162.774 170.915 1.00 43.24 ?  105 LEU   A CD1 1 
ATOM   680  C CD2 . LEU   A 1 105 ? 204.066 160.418 171.292 1.00 43.24 ?  105 LEU   A CD2 1 
ATOM   681  N N   . ILE   A 1 106 ? 200.459 160.983 166.509 1.00 41.76 ?  106 ILE   A N   1 
ATOM   682  C CA  . ILE   A 1 106 ? 199.476 160.164 165.801 1.00 41.76 ?  106 ILE   A CA  1 
ATOM   683  C C   . ILE   A 1 106 ? 199.579 160.469 164.312 1.00 41.76 ?  106 ILE   A C   1 
ATOM   684  O O   . ILE   A 1 106 ? 199.671 161.644 163.940 1.00 41.76 ?  106 ILE   A O   1 
ATOM   685  C CB  . ILE   A 1 106 ? 198.044 160.426 166.306 1.00 41.76 ?  106 ILE   A CB  1 
ATOM   686  C CG1 . ILE   A 1 106 ? 197.807 159.693 167.627 1.00 41.76 ?  106 ILE   A CG1 1 
ATOM   687  C CG2 . ILE   A 1 106 ? 197.027 159.984 165.265 1.00 41.76 ?  106 ILE   A CG2 1 
ATOM   688  C CD1 . ILE   A 1 106 ? 196.486 160.030 168.294 1.00 41.76 ?  106 ILE   A CD1 1 
ATOM   689  N N   . PRO   A 1 107 ? 199.556 159.460 163.432 1.00 43.51 ?  107 PRO   A N   1 
ATOM   690  C CA  . PRO   A 1 107 ? 199.541 159.738 161.989 1.00 43.51 ?  107 PRO   A CA  1 
ATOM   691  C C   . PRO   A 1 107 ? 198.346 160.577 161.562 1.00 43.51 ?  107 PRO   A C   1 
ATOM   692  O O   . PRO   A 1 107 ? 197.280 160.505 162.178 1.00 43.51 ?  107 PRO   A O   1 
ATOM   693  C CB  . PRO   A 1 107 ? 199.496 158.339 161.368 1.00 43.51 ?  107 PRO   A CB  1 
ATOM   694  C CG  . PRO   A 1 107 ? 200.181 157.479 162.362 1.00 43.51 ?  107 PRO   A CG  1 
ATOM   695  C CD  . PRO   A 1 107 ? 199.804 158.034 163.707 1.00 43.51 ?  107 PRO   A CD  1 
ATOM   696  N N   . PHE   A 1 108 ? 198.513 161.366 160.496 1.00 43.12 ?  108 PHE   A N   1 
ATOM   697  C CA  . PHE   A 1 108 ? 197.528 162.393 160.167 1.00 43.12 ?  108 PHE   A CA  1 
ATOM   698  C C   . PHE   A 1 108 ? 196.153 161.809 159.872 1.00 43.12 ?  108 PHE   A C   1 
ATOM   699  O O   . PHE   A 1 108 ? 195.144 162.381 160.290 1.00 43.12 ?  108 PHE   A O   1 
ATOM   700  C CB  . PHE   A 1 108 ? 198.012 163.217 158.976 1.00 43.12 ?  108 PHE   A CB  1 
ATOM   701  C CG  . PHE   A 1 108 ? 198.948 164.332 159.351 1.00 43.12 ?  108 PHE   A CG  1 
ATOM   702  C CD1 . PHE   A 1 108 ? 200.251 164.062 159.737 1.00 43.12 ?  108 PHE   A CD1 1 
ATOM   703  C CD2 . PHE   A 1 108 ? 198.526 165.649 159.314 1.00 43.12 ?  108 PHE   A CD2 1 
ATOM   704  C CE1 . PHE   A 1 108 ? 201.114 165.087 160.082 1.00 43.12 ?  108 PHE   A CE1 1 
ATOM   705  C CE2 . PHE   A 1 108 ? 199.387 166.677 159.658 1.00 43.12 ?  108 PHE   A CE2 1 
ATOM   706  C CZ  . PHE   A 1 108 ? 200.680 166.395 160.042 1.00 43.12 ?  108 PHE   A CZ  1 
ATOM   707  N N   . THR   A 1 109 ? 196.079 160.697 159.141 1.00 42.08 ?  109 THR   A N   1 
ATOM   708  C CA  . THR   A 1 109 ? 194.774 160.131 158.808 1.00 42.08 ?  109 THR   A CA  1 
ATOM   709  C C   . THR   A 1 109 ? 194.111 159.489 160.022 1.00 42.08 ?  109 THR   A C   1 
ATOM   710  O O   . THR   A 1 109 ? 192.896 159.631 160.225 1.00 42.08 ?  109 THR   A O   1 
ATOM   711  C CB  . THR   A 1 109 ? 194.919 159.104 157.686 1.00 42.08 ?  109 THR   A CB  1 
ATOM   712  O OG1 . THR   A 1 109 ? 195.804 158.057 158.104 1.00 42.08 ?  109 THR   A OG1 1 
ATOM   713  C CG2 . THR   A 1 109 ? 195.464 159.758 156.423 1.00 42.08 ?  109 THR   A CG2 1 
ATOM   714  N N   . LEU   A 1 110 ? 194.892 158.762 160.824 1.00 41.25 ?  110 LEU   A N   1 
ATOM   715  C CA  . LEU   A 1 110 ? 194.376 158.182 162.056 1.00 41.25 ?  110 LEU   A CA  1 
ATOM   716  C C   . LEU   A 1 110 ? 193.818 159.240 162.989 1.00 41.25 ?  110 LEU   A C   1 
ATOM   717  O O   . LEU   A 1 110 ? 192.963 158.925 163.822 1.00 41.25 ?  110 LEU   A O   1 
ATOM   718  C CB  . LEU   A 1 110 ? 195.478 157.399 162.775 1.00 41.25 ?  110 LEU   A CB  1 
ATOM   719  C CG  . LEU   A 1 110 ? 195.798 155.992 162.261 1.00 41.25 ?  110 LEU   A CG  1 
ATOM   720  C CD1 . LEU   A 1 110 ? 194.626 155.052 162.499 1.00 41.25 ?  110 LEU   A CD1 1 
ATOM   721  C CD2 . LEU   A 1 110 ? 196.179 156.015 160.789 1.00 41.25 ?  110 LEU   A CD2 1 
ATOM   722  N N   . LEU   A 1 111 ? 194.285 160.481 162.872 1.00 40.84 ?  111 LEU   A N   1 
ATOM   723  C CA  . LEU   A 1 111 ? 193.736 161.591 163.627 1.00 40.84 ?  111 LEU   A CA  1 
ATOM   724  C C   . LEU   A 1 111 ? 192.585 162.283 162.921 1.00 40.84 ?  111 LEU   A C   1 
ATOM   725  O O   . LEU   A 1 111 ? 191.670 162.747 163.596 1.00 40.84 ?  111 LEU   A O   1 
ATOM   726  C CB  . LEU   A 1 111 ? 194.829 162.625 163.923 1.00 40.84 ?  111 LEU   A CB  1 
ATOM   727  C CG  . LEU   A 1 111 ? 194.381 163.911 164.609 1.00 40.84 ?  111 LEU   A CG  1 
ATOM   728  C CD1 . LEU   A 1 111 ? 193.805 163.611 165.978 1.00 40.84 ?  111 LEU   A CD1 1 
ATOM   729  C CD2 . LEU   A 1 111 ? 195.551 164.860 164.718 1.00 40.84 ?  111 LEU   A CD2 1 
ATOM   730  N N   . GLY   A 1 112 ? 192.597 162.355 161.591 1.00 40.69 ?  112 GLY   A N   1 
ATOM   731  C CA  . GLY   A 1 112 ? 191.495 162.994 160.888 1.00 40.69 ?  112 GLY   A CA  1 
ATOM   732  C C   . GLY   A 1 112 ? 190.196 162.222 161.024 1.00 40.69 ?  112 GLY   A C   1 
ATOM   733  O O   . GLY   A 1 112 ? 189.148 162.793 161.346 1.00 40.69 ?  112 GLY   A O   1 
ATOM   734  N N   . LEU   A 1 113 ? 190.246 160.910 160.784 1.00 40.35 ?  113 LEU   A N   1 
ATOM   735  C CA  . LEU   A 1 113 ? 189.042 160.103 160.967 1.00 40.35 ?  113 LEU   A CA  1 
ATOM   736  C C   . LEU   A 1 113 ? 188.599 160.124 162.422 1.00 40.35 ?  113 LEU   A C   1 
ATOM   737  O O   . LEU   A 1 113 ? 187.401 160.235 162.716 1.00 40.35 ?  113 LEU   A O   1 
ATOM   738  C CB  . LEU   A 1 113 ? 189.284 158.671 160.490 1.00 40.35 ?  113 LEU   A CB  1 
ATOM   739  C CG  . LEU   A 1 113 ? 190.309 157.832 161.256 1.00 40.35 ?  113 LEU   A CG  1 
ATOM   740  C CD1 . LEU   A 1 113 ? 189.645 157.011 162.356 1.00 40.35 ?  113 LEU   A CD1 1 
ATOM   741  C CD2 . LEU   A 1 113 ? 191.075 156.929 160.299 1.00 40.35 ?  113 LEU   A CD2 1 
ATOM   742  N N   . CYS   A 1 114 ? 189.556 160.039 163.346 1.00 41.83 ?  114 CYS   A N   1 
ATOM   743  C CA  . CYS   A 1 114 ? 189.224 160.099 164.762 1.00 41.83 ?  114 CYS   A CA  1 
ATOM   744  C C   . CYS   A 1 114 ? 188.551 161.419 165.106 1.00 41.83 ?  114 CYS   A C   1 
ATOM   745  O O   . CYS   A 1 114 ? 187.593 161.447 165.880 1.00 41.83 ?  114 CYS   A O   1 
ATOM   746  C CB  . CYS   A 1 114 ? 190.486 159.903 165.603 1.00 41.83 ?  114 CYS   A CB  1 
ATOM   747  S SG  . CYS   A 1 114 ? 190.228 160.013 167.390 1.00 41.83 ?  114 CYS   A SG  1 
ATOM   748  N N   . TRP   A 1 115 ? 189.029 162.522 164.532 1.00 40.50 ?  115 TRP   A N   1 
ATOM   749  C CA  . TRP   A 1 115 ? 188.468 163.828 164.854 1.00 40.50 ?  115 TRP   A CA  1 
ATOM   750  C C   . TRP   A 1 115 ? 187.072 163.987 164.277 1.00 40.50 ?  115 TRP   A C   1 
ATOM   751  O O   . TRP   A 1 115 ? 186.195 164.568 164.921 1.00 40.50 ?  115 TRP   A O   1 
ATOM   752  C CB  . TRP   A 1 115 ? 189.383 164.933 164.335 1.00 40.50 ?  115 TRP   A CB  1 
ATOM   753  C CG  . TRP   A 1 115 ? 189.477 166.101 165.253 1.00 40.50 ?  115 TRP   A CG  1 
ATOM   754  C CD1 . TRP   A 1 115 ? 188.822 167.289 165.139 1.00 40.50 ?  115 TRP   A CD1 1 
ATOM   755  C CD2 . TRP   A 1 115 ? 190.277 166.194 166.434 1.00 40.50 ?  115 TRP   A CD2 1 
ATOM   756  N NE1 . TRP   A 1 115 ? 189.168 168.120 166.175 1.00 40.50 ?  115 TRP   A NE1 1 
ATOM   757  C CE2 . TRP   A 1 115 ? 190.060 167.470 166.986 1.00 40.50 ?  115 TRP   A CE2 1 
ATOM   758  C CE3 . TRP   A 1 115 ? 191.158 165.320 167.079 1.00 40.50 ?  115 TRP   A CE3 1 
ATOM   759  C CZ2 . TRP   A 1 115 ? 190.692 167.894 168.152 1.00 40.50 ?  115 TRP   A CZ2 1 
ATOM   760  C CZ3 . TRP   A 1 115 ? 191.783 165.742 168.235 1.00 40.50 ?  115 TRP   A CZ3 1 
ATOM   761  C CH2 . TRP   A 1 115 ? 191.547 167.018 168.761 1.00 40.50 ?  115 TRP   A CH2 1 
ATOM   762  N N   . ILE   A 1 116 ? 186.845 163.496 163.058 1.00 39.59 ?  116 ILE   A N   1 
ATOM   763  C CA  . ILE   A 1 116 ? 185.500 163.571 162.493 1.00 39.59 ?  116 ILE   A CA  1 
ATOM   764  C C   . ILE   A 1 116 ? 184.532 162.756 163.342 1.00 39.59 ?  116 ILE   A C   1 
ATOM   765  O O   . ILE   A 1 116 ? 183.446 163.228 163.708 1.00 39.59 ?  116 ILE   A O   1 
ATOM   766  C CB  . ILE   A 1 116 ? 185.499 163.105 161.026 1.00 39.59 ?  116 ILE   A CB  1 
ATOM   767  C CG1 . ILE   A 1 116 ? 186.383 164.014 160.167 1.00 39.59 ?  116 ILE   A CG1 1 
ATOM   768  C CG2 . ILE   A 1 116 ? 184.082 163.085 160.479 1.00 39.59 ?  116 ILE   A CG2 1 
ATOM   769  C CD1 . ILE   A 1 116 ? 186.057 165.487 160.275 1.00 39.59 ?  116 ILE   A CD1 1 
ATOM   770  N N   . LEU   A 1 117 ? 184.918 161.525 163.689 1.00 39.53 ?  117 LEU   A N   1 
ATOM   771  C CA  . LEU   A 1 117 ? 184.059 160.713 164.544 1.00 39.53 ?  117 LEU   A CA  1 
ATOM   772  C C   . LEU   A 1 117 ? 183.845 161.385 165.892 1.00 39.53 ?  117 LEU   A C   1 
ATOM   773  O O   . LEU   A 1 117 ? 182.745 161.333 166.452 1.00 39.53 ?  117 LEU   A O   1 
ATOM   774  C CB  . LEU   A 1 117 ? 184.658 159.319 164.732 1.00 39.53 ?  117 LEU   A CB  1 
ATOM   775  C CG  . LEU   A 1 117 ? 184.862 158.456 163.485 1.00 39.53 ?  117 LEU   A CG  1 
ATOM   776  C CD1 . LEU   A 1 117 ? 184.915 156.987 163.867 1.00 39.53 ?  117 LEU   A CD1 1 
ATOM   777  C CD2 . LEU   A 1 117 ? 183.775 158.698 162.455 1.00 39.53 ?  117 LEU   A CD2 1 
ATOM   778  N N   . GLY   A 1 118 ? 184.886 162.015 166.434 1.00 39.14 ?  118 GLY   A N   1 
ATOM   779  C CA  . GLY   A 1 118 ? 184.754 162.676 167.718 1.00 39.14 ?  118 GLY   A CA  1 
ATOM   780  C C   . GLY   A 1 118 ? 183.808 163.855 167.666 1.00 39.14 ?  118 GLY   A C   1 
ATOM   781  O O   . GLY   A 1 118 ? 183.014 164.061 168.580 1.00 39.14 ?  118 GLY   A O   1 
ATOM   782  N N   . THR   A 1 119 ? 183.881 164.648 166.598 1.00 39.58 ?  119 THR   A N   1 
ATOM   783  C CA  . THR   A 1 119 ? 182.953 165.762 166.447 1.00 39.58 ?  119 THR   A CA  1 
ATOM   784  C C   . THR   A 1 119 ? 181.522 165.260 166.311 1.00 39.58 ?  119 THR   A C   1 
ATOM   785  O O   . THR   A 1 119 ? 180.594 165.834 166.893 1.00 39.58 ?  119 THR   A O   1 
ATOM   786  C CB  . THR   A 1 119 ? 183.339 166.612 165.238 1.00 39.58 ?  119 THR   A CB  1 
ATOM   787  O OG1 . THR   A 1 119 ? 184.637 167.181 165.443 1.00 39.58 ?  119 THR   A OG1 1 
ATOM   788  C CG2 . THR   A 1 119 ? 182.329 167.726 165.026 1.00 39.58 ?  119 THR   A CG2 1 
ATOM   789  N N   . ILE   A 1 120 ? 181.325 164.182 165.552 1.00 39.87 ?  120 ILE   A N   1 
ATOM   790  C CA  . ILE   A 1 120 ? 179.984 163.624 165.398 1.00 39.87 ?  120 ILE   A CA  1 
ATOM   791  C C   . ILE   A 1 120 ? 179.450 163.141 166.743 1.00 39.87 ?  120 ILE   A C   1 
ATOM   792  O O   . ILE   A 1 120 ? 178.312 163.442 167.133 1.00 39.87 ?  120 ILE   A O   1 
ATOM   793  C CB  . ILE   A 1 120 ? 180.003 162.484 164.366 1.00 39.87 ?  120 ILE   A CB  1 
ATOM   794  C CG1 . ILE   A 1 120 ? 180.499 162.989 163.003 1.00 39.87 ?  120 ILE   A CG1 1 
ATOM   795  C CG2 . ILE   A 1 120 ? 178.637 161.834 164.282 1.00 39.87 ?  120 ILE   A CG2 1 
ATOM   796  C CD1 . ILE   A 1 120 ? 179.504 163.793 162.221 1.00 39.87 ?  120 ILE   A CD1 1 
ATOM   797  N N   . ALA   A 1 121 ? 180.265 162.373 167.468 1.00 39.04 ?  121 ALA   A N   1 
ATOM   798  C CA  . ALA   A 1 121 ? 179.845 161.862 168.764 1.00 39.04 ?  121 ALA   A CA  1 
ATOM   799  C C   . ALA   A 1 121 ? 179.628 162.990 169.755 1.00 39.04 ?  121 ALA   A C   1 
ATOM   800  O O   . ALA   A 1 121 ? 178.751 162.896 170.615 1.00 39.04 ?  121 ALA   A O   1 
ATOM   801  C CB  . ALA   A 1 121 ? 180.881 160.875 169.301 1.00 39.04 ?  121 ALA   A CB  1 
ATOM   802  N N   . ALA   A 1 122 ? 180.411 164.063 169.653 1.00 39.94 ?  122 ALA   A N   1 
ATOM   803  C CA  . ALA   A 1 122 ? 180.208 165.214 170.520 1.00 39.94 ?  122 ALA   A CA  1 
ATOM   804  C C   . ALA   A 1 122 ? 178.892 165.903 170.205 1.00 39.94 ?  122 ALA   A C   1 
ATOM   805  O O   . ALA   A 1 122 ? 178.204 166.374 171.113 1.00 39.94 ?  122 ALA   A O   1 
ATOM   806  C CB  . ALA   A 1 122 ? 181.373 166.191 170.379 1.00 39.94 ?  122 ALA   A CB  1 
ATOM   807  N N   . LEU   A 1 123 ? 178.524 165.977 168.926 1.00 40.73 ?  123 LEU   A N   1 
ATOM   808  C CA  . LEU   A 1 123 ? 177.219 166.527 168.577 1.00 40.73 ?  123 LEU   A CA  1 
ATOM   809  C C   . LEU   A 1 123 ? 176.096 165.678 169.159 1.00 40.73 ?  123 LEU   A C   1 
ATOM   810  O O   . LEU   A 1 123 ? 175.135 166.206 169.733 1.00 40.73 ?  123 LEU   A O   1 
ATOM   811  C CB  . LEU   A 1 123 ? 177.075 166.628 167.060 1.00 40.73 ?  123 LEU   A CB  1 
ATOM   812  C CG  . LEU   A 1 123 ? 175.994 167.573 166.526 1.00 40.73 ?  123 LEU   A CG  1 
ATOM   813  C CD1 . LEU   A 1 123 ? 175.967 168.905 167.265 1.00 40.73 ?  123 LEU   A CD1 1 
ATOM   814  C CD2 . LEU   A 1 123 ? 176.197 167.792 165.042 1.00 40.73 ?  123 LEU   A CD2 1 
ATOM   815  N N   . TYR   A 1 124 ? 176.203 164.357 169.029 1.00 40.82 ?  124 TYR   A N   1 
ATOM   816  C CA  . TYR   A 1 124 ? 175.172 163.497 169.603 1.00 40.82 ?  124 TYR   A CA  1 
ATOM   817  C C   . TYR   A 1 124 ? 175.121 163.641 171.119 1.00 40.82 ?  124 TYR   A C   1 
ATOM   818  O O   . TYR   A 1 124 ? 174.037 163.726 171.709 1.00 40.82 ?  124 TYR   A O   1 
ATOM   819  C CB  . TYR   A 1 124 ? 175.412 162.040 169.222 1.00 40.82 ?  124 TYR   A CB  1 
ATOM   820  C CG  . TYR   A 1 124 ? 174.611 161.076 170.066 1.00 40.82 ?  124 TYR   A CG  1 
ATOM   821  C CD1 . TYR   A 1 124 ? 173.225 161.129 170.083 1.00 40.82 ?  124 TYR   A CD1 1 
ATOM   822  C CD2 . TYR   A 1 124 ? 175.240 160.124 170.854 1.00 40.82 ?  124 TYR   A CD2 1 
ATOM   823  C CE1 . TYR   A 1 124 ? 172.488 160.257 170.854 1.00 40.82 ?  124 TYR   A CE1 1 
ATOM   824  C CE2 . TYR   A 1 124 ? 174.509 159.247 171.630 1.00 40.82 ?  124 TYR   A CE2 1 
ATOM   825  C CZ  . TYR   A 1 124 ? 173.134 159.318 171.625 1.00 40.82 ?  124 TYR   A CZ  1 
ATOM   826  O OH  . TYR   A 1 124 ? 172.403 158.446 172.396 1.00 40.82 ?  124 TYR   A OH  1 
ATOM   827  N N   . ALA   A 1 125 ? 176.284 163.676 171.766 1.00 39.80 ?  125 ALA   A N   1 
ATOM   828  C CA  . ALA   A 1 125 ? 176.325 163.778 173.217 1.00 39.80 ?  125 ALA   A CA  1 
ATOM   829  C C   . ALA   A 1 125 ? 175.784 165.117 173.691 1.00 39.80 ?  125 ALA   A C   1 
ATOM   830  O O   . ALA   A 1 125 ? 175.110 165.184 174.719 1.00 39.80 ?  125 ALA   A O   1 
ATOM   831  C CB  . ALA   A 1 125 ? 177.753 163.570 173.715 1.00 39.80 ?  125 ALA   A CB  1 
ATOM   832  N N   . VAL   A 1 126 ? 176.075 166.198 172.967 1.00 39.83 ?  126 VAL   A N   1 
ATOM   833  C CA  . VAL   A 1 126 ? 175.577 167.503 173.377 1.00 39.83 ?  126 VAL   A CA  1 
ATOM   834  C C   . VAL   A 1 126 ? 174.074 167.589 173.165 1.00 39.83 ?  126 VAL   A C   1 
ATOM   835  O O   . VAL   A 1 126 ? 173.367 168.212 173.963 1.00 39.83 ?  126 VAL   A O   1 
ATOM   836  C CB  . VAL   A 1 126 ? 176.330 168.624 172.638 1.00 39.83 ?  126 VAL   A CB  1 
ATOM   837  C CG1 . VAL   A 1 126 ? 176.002 168.625 171.171 1.00 39.83 ?  126 VAL   A CG1 1 
ATOM   838  C CG2 . VAL   A 1 126 ? 176.013 169.958 173.250 1.00 39.83 ?  126 VAL   A CG2 1 
ATOM   839  N N   . VAL   A 1 127 ? 173.551 166.965 172.108 1.00 40.69 ?  127 VAL   A N   1 
ATOM   840  C CA  . VAL   A 1 127 ? 172.100 166.894 171.962 1.00 40.69 ?  127 VAL   A CA  1 
ATOM   841  C C   . VAL   A 1 127 ? 171.489 166.109 173.117 1.00 40.69 ?  127 VAL   A C   1 
ATOM   842  O O   . VAL   A 1 127 ? 170.447 166.490 173.664 1.00 40.69 ?  127 VAL   A O   1 
ATOM   843  C CB  . VAL   A 1 127 ? 171.725 166.280 170.602 1.00 40.69 ?  127 VAL   A CB  1 
ATOM   844  C CG1 . VAL   A 1 127 ? 170.247 165.942 170.570 1.00 40.69 ?  127 VAL   A CG1 1 
ATOM   845  C CG2 . VAL   A 1 127 ? 172.076 167.236 169.478 1.00 40.69 ?  127 VAL   A CG2 1 
ATOM   846  N N   . ARG   A 1 128 ? 172.120 164.997 173.502 1.00 41.66 ?  128 ARG   A N   1 
ATOM   847  C CA  . ARG   A 1 128 ? 171.611 164.212 174.622 1.00 41.66 ?  128 ARG   A CA  1 
ATOM   848  C C   . ARG   A 1 128 ? 171.656 165.009 175.920 1.00 41.66 ?  128 ARG   A C   1 
ATOM   849  O O   . ARG   A 1 128 ? 170.731 164.934 176.736 1.00 41.66 ?  128 ARG   A O   1 
ATOM   850  C CB  . ARG   A 1 128 ? 172.413 162.920 174.761 1.00 41.66 ?  128 ARG   A CB  1 
ATOM   851  C CG  . ARG   A 1 128 ? 171.715 161.849 175.575 1.00 41.66 ?  128 ARG   A CG  1 
ATOM   852  C CD  . ARG   A 1 128 ? 171.043 160.820 174.682 1.00 41.66 ?  128 ARG   A CD  1 
ATOM   853  N NE  . ARG   A 1 128 ? 170.516 159.695 175.444 1.00 41.66 ?  128 ARG   A NE  1 
ATOM   854  C CZ  . ARG   A 1 128 ? 171.239 158.666 175.866 1.00 41.66 ?  128 ARG   A CZ  1 
ATOM   855  N NH1 . ARG   A 1 128 ? 172.536 158.582 175.615 1.00 41.66 1  128 ARG   A NH1 1 
ATOM   856  N NH2 . ARG   A 1 128 ? 170.647 157.697 176.557 1.00 41.66 ?  128 ARG   A NH2 1 
ATOM   857  N N   . LEU   A 1 129 ? 172.734 165.764 176.139 1.00 40.49 ?  129 LEU   A N   1 
ATOM   858  C CA  . LEU   A 1 129 ? 172.821 166.611 177.323 1.00 40.49 ?  129 LEU   A CA  1 
ATOM   859  C C   . LEU   A 1 129 ? 171.761 167.700 177.302 1.00 40.49 ?  129 LEU   A C   1 
ATOM   860  O O   . LEU   A 1 129 ? 171.199 168.039 178.345 1.00 40.49 ?  129 LEU   A O   1 
ATOM   861  C CB  . LEU   A 1 129 ? 174.216 167.228 177.446 1.00 40.49 ?  129 LEU   A CB  1 
ATOM   862  C CG  . LEU   A 1 129 ? 175.317 166.422 178.148 1.00 40.49 ?  129 LEU   A CG  1 
ATOM   863  C CD1 . LEU   A 1 129 ? 174.960 166.220 179.614 1.00 40.49 ?  129 LEU   A CD1 1 
ATOM   864  C CD2 . LEU   A 1 129 ? 175.596 165.081 177.487 1.00 40.49 ?  129 LEU   A CD2 1 
ATOM   865  N N   . SER   A 1 130 ? 171.481 168.272 176.132 1.00 41.00 ?  130 SER   A N   1 
ATOM   866  C CA  . SER   A 1 130 ? 170.410 169.257 176.045 1.00 41.00 ?  130 SER   A CA  1 
ATOM   867  C C   . SER   A 1 130 ? 169.070 168.630 176.401 1.00 41.00 ?  130 SER   A C   1 
ATOM   868  O O   . SER   A 1 130 ? 168.268 169.222 177.134 1.00 41.00 ?  130 SER   A O   1 
ATOM   869  C CB  . SER   A 1 130 ? 170.368 169.862 174.644 1.00 41.00 ?  130 SER   A CB  1 
ATOM   870  O OG  . SER   A 1 130 ? 169.421 170.911 174.576 1.00 41.00 ?  130 SER   A OG  1 
ATOM   871  N N   . GLN   A 1 131 ? 168.814 167.421 175.899 1.00 41.34 ?  131 GLN   A N   1 
ATOM   872  C CA  . GLN   A 1 131 ? 167.582 166.725 176.250 1.00 41.34 ?  131 GLN   A CA  1 
ATOM   873  C C   . GLN   A 1 131 ? 167.503 166.478 177.751 1.00 41.34 ?  131 GLN   A C   1 
ATOM   874  O O   . GLN   A 1 131 ? 166.456 166.696 178.371 1.00 41.34 ?  131 GLN   A O   1 
ATOM   875  C CB  . GLN   A 1 131 ? 167.493 165.406 175.489 1.00 41.34 ?  131 GLN   A CB  1 
ATOM   876  C CG  . GLN   A 1 131 ? 167.093 165.552 174.034 1.00 41.34 ?  131 GLN   A CG  1 
ATOM   877  C CD  . GLN   A 1 131 ? 167.010 164.223 173.296 1.00 41.34 ?  131 GLN   A CD  1 
ATOM   878  O OE1 . GLN   A 1 131 ? 166.541 164.170 172.159 1.00 41.34 ?  131 GLN   A OE1 1 
ATOM   879  N NE2 . GLN   A 1 131 ? 167.466 163.145 173.932 1.00 41.34 ?  131 GLN   A NE2 1 
ATOM   880  N N   . ARG   A 1 132 ? 168.604 166.025 178.352 1.00 40.53 ?  132 ARG   A N   1 
ATOM   881  C CA  . ARG   A 1 132 ? 168.620 165.799 179.794 1.00 40.53 ?  132 ARG   A CA  1 
ATOM   882  C C   . ARG   A 1 132 ? 168.364 167.096 180.549 1.00 40.53 ?  132 ARG   A C   1 
ATOM   883  O O   . ARG   A 1 132 ? 167.635 167.111 181.548 1.00 40.53 ?  132 ARG   A O   1 
ATOM   884  C CB  . ARG   A 1 132 ? 169.959 165.190 180.211 1.00 40.53 ?  132 ARG   A CB  1 
ATOM   885  C CG  . ARG   A 1 132 ? 170.056 163.685 180.002 1.00 40.53 ?  132 ARG   A CG  1 
ATOM   886  C CD  . ARG   A 1 132 ? 171.498 163.196 180.071 1.00 40.53 ?  132 ARG   A CD  1 
ATOM   887  N NE  . ARG   A 1 132 ? 171.932 162.939 181.441 1.00 40.53 ?  132 ARG   A NE  1 
ATOM   888  C CZ  . ARG   A 1 132 ? 173.173 163.093 181.886 1.00 40.53 ?  132 ARG   A CZ  1 
ATOM   889  N NH1 . ARG   A 1 132 ? 174.150 163.503 181.094 1.00 40.53 1  132 ARG   A NH1 1 
ATOM   890  N NH2 . ARG   A 1 132 ? 173.443 162.824 183.160 1.00 40.53 ?  132 ARG   A NH2 1 
ATOM   891  N N   . LEU   A 1 133 ? 168.955 168.196 180.084 1.00 40.10 ?  133 LEU   A N   1 
ATOM   892  C CA  . LEU   A 1 133 ? 168.737 169.489 180.718 1.00 40.10 ?  133 LEU   A CA  1 
ATOM   893  C C   . LEU   A 1 133 ? 167.270 169.884 180.657 1.00 40.10 ?  133 LEU   A C   1 
ATOM   894  O O   . LEU   A 1 133 ? 166.719 170.413 181.629 1.00 40.10 ?  133 LEU   A O   1 
ATOM   895  C CB  . LEU   A 1 133 ? 169.603 170.551 180.042 1.00 40.10 ?  133 LEU   A CB  1 
ATOM   896  C CG  . LEU   A 1 133 ? 170.901 170.935 180.751 1.00 40.10 ?  133 LEU   A CG  1 
ATOM   897  C CD1 . LEU   A 1 133 ? 171.775 169.720 180.990 1.00 40.10 ?  133 LEU   A CD1 1 
ATOM   898  C CD2 . LEU   A 1 133 ? 171.650 171.971 179.936 1.00 40.10 ?  133 LEU   A CD2 1 
ATOM   899  N N   . LEU   A 1 134 ? 166.620 169.637 179.520 1.00 41.27 ?  134 LEU   A N   1 
ATOM   900  C CA  . LEU   A 1 134 ? 165.204 169.953 179.390 1.00 41.27 ?  134 LEU   A CA  1 
ATOM   901  C C   . LEU   A 1 134 ? 164.321 169.037 180.225 1.00 41.27 ?  134 LEU   A C   1 
ATOM   902  O O   . LEU   A 1 134 ? 163.122 169.308 180.346 1.00 41.27 ?  134 LEU   A O   1 
ATOM   903  C CB  . LEU   A 1 134 ? 164.784 169.877 177.924 1.00 41.27 ?  134 LEU   A CB  1 
ATOM   904  C CG  . LEU   A 1 134 ? 165.442 170.907 177.008 1.00 41.27 ?  134 LEU   A CG  1 
ATOM   905  C CD1 . LEU   A 1 134 ? 164.951 170.732 175.589 1.00 41.27 ?  134 LEU   A CD1 1 
ATOM   906  C CD2 . LEU   A 1 134 ? 165.175 172.317 177.500 1.00 41.27 ?  134 LEU   A CD2 1 
ATOM   907  N N   . GLY   A 1 135 ? 164.874 167.971 180.792 1.00 41.64 ?  135 GLY   A N   1 
ATOM   908  C CA  . GLY   A 1 135 ? 164.137 167.109 181.688 1.00 41.64 ?  135 GLY   A CA  1 
ATOM   909  C C   . GLY   A 1 135 ? 163.662 165.799 181.104 1.00 41.64 ?  135 GLY   A C   1 
ATOM   910  O O   . GLY   A 1 135 ? 162.919 165.080 181.780 1.00 41.64 ?  135 GLY   A O   1 
ATOM   911  N N   . PHE   A 1 136 ? 164.057 165.463 179.879 1.00 40.91 ?  136 PHE   A N   1 
ATOM   912  C CA  . PHE   A 1 136 ? 163.659 164.204 179.268 1.00 40.91 ?  136 PHE   A CA  1 
ATOM   913  C C   . PHE   A 1 136 ? 164.848 163.578 178.559 1.00 40.91 ?  136 PHE   A C   1 
ATOM   914  O O   . PHE   A 1 136 ? 165.658 164.281 177.951 1.00 40.91 ?  136 PHE   A O   1 
ATOM   915  C CB  . PHE   A 1 136 ? 162.507 164.401 178.276 1.00 40.91 ?  136 PHE   A CB  1 
ATOM   916  C CG  . PHE   A 1 136 ? 162.891 165.167 177.045 1.00 40.91 ?  136 PHE   A CG  1 
ATOM   917  C CD1 . PHE   A 1 136 ? 162.930 166.549 177.058 1.00 40.91 ?  136 PHE   A CD1 1 
ATOM   918  C CD2 . PHE   A 1 136 ? 163.206 164.506 175.873 1.00 40.91 ?  136 PHE   A CD2 1 
ATOM   919  C CE1 . PHE   A 1 136 ? 163.279 167.255 175.928 1.00 40.91 ?  136 PHE   A CE1 1 
ATOM   920  C CE2 . PHE   A 1 136 ? 163.557 165.207 174.742 1.00 40.91 ?  136 PHE   A CE2 1 
ATOM   921  C CZ  . PHE   A 1 136 ? 163.593 166.583 174.770 1.00 40.91 ?  136 PHE   A CZ  1 
ATOM   922  N N   . ASP   A 1 137 ? 164.944 162.256 178.642 1.00 41.79 ?  137 ASP   A N   1 
ATOM   923  C CA  . ASP   A 1 137 ? 165.970 161.492 177.947 1.00 41.79 ?  137 ASP   A CA  1 
ATOM   924  C C   . ASP   A 1 137 ? 165.336 160.756 176.777 1.00 41.79 ?  137 ASP   A C   1 
ATOM   925  O O   . ASP   A 1 137 ? 164.333 160.056 176.949 1.00 41.79 ?  137 ASP   A O   1 
ATOM   926  C CB  . ASP   A 1 137 ? 166.643 160.495 178.889 1.00 41.79 ?  137 ASP   A CB  1 
ATOM   927  C CG  . ASP   A 1 137 ? 167.610 159.581 178.170 1.00 41.79 ?  137 ASP   A CG  1 
ATOM   928  O OD1 . ASP   A 1 137 ? 168.139 159.988 177.116 1.00 41.79 ?  137 ASP   A OD1 1 
ATOM   929  O OD2 . ASP   A 1 137 ? 167.838 158.453 178.655 1.00 41.79 -1 137 ASP   A OD2 1 
ATOM   930  N N   . ASP   A 1 138 ? 165.923 160.912 175.591 1.00 42.00 ?  138 ASP   A N   1 
ATOM   931  C CA  . ASP   A 1 138 ? 165.380 160.294 174.383 1.00 42.00 ?  138 ASP   A CA  1 
ATOM   932  C C   . ASP   A 1 138 ? 166.544 160.058 173.424 1.00 42.00 ?  138 ASP   A C   1 
ATOM   933  O O   . ASP   A 1 138 ? 166.989 160.988 172.745 1.00 42.00 ?  138 ASP   A O   1 
ATOM   934  C CB  . ASP   A 1 138 ? 164.307 161.174 173.758 1.00 42.00 ?  138 ASP   A CB  1 
ATOM   935  C CG  . ASP   A 1 138 ? 163.298 160.384 172.951 1.00 42.00 ?  138 ASP   A CG  1 
ATOM   936  O OD1 . ASP   A 1 138 ? 163.468 159.155 172.818 1.00 42.00 ?  138 ASP   A OD1 1 
ATOM   937  O OD2 . ASP   A 1 138 ? 162.332 160.994 172.449 1.00 42.00 -1 138 ASP   A OD2 1 
ATOM   938  N N   . ALA   A 1 139 ? 167.035 158.818 173.382 1.00 42.61 ?  139 ALA   A N   1 
ATOM   939  C CA  . ALA   A 1 139 ? 168.140 158.495 172.486 1.00 42.61 ?  139 ALA   A CA  1 
ATOM   940  C C   . ALA   A 1 139 ? 167.721 158.610 171.026 1.00 42.61 ?  139 ALA   A C   1 
ATOM   941  O O   . ALA   A 1 139 ? 168.480 159.121 170.195 1.00 42.61 ?  139 ALA   A O   1 
ATOM   942  C CB  . ALA   A 1 139 ? 168.662 157.091 172.784 1.00 42.61 ?  139 ALA   A CB  1 
ATOM   943  N N   . ARG   A 1 140 ? 166.519 158.139 170.692 1.00 43.16 ?  140 ARG   A N   1 
ATOM   944  C CA  . ARG   A 1 140 ? 166.065 158.192 169.307 1.00 43.16 ?  140 ARG   A CA  1 
ATOM   945  C C   . ARG   A 1 140 ? 165.905 159.631 168.833 1.00 43.16 ?  140 ARG   A C   1 
ATOM   946  O O   . ARG   A 1 140 ? 166.375 159.993 167.746 1.00 43.16 ?  140 ARG   A O   1 
ATOM   947  C CB  . ARG   A 1 140 ? 164.747 157.434 169.170 1.00 43.16 ?  140 ARG   A CB  1 
ATOM   948  C CG  . ARG   A 1 140 ? 164.905 155.951 168.883 1.00 43.16 ?  140 ARG   A CG  1 
ATOM   949  C CD  . ARG   A 1 140 ? 165.201 155.167 170.149 1.00 43.16 ?  140 ARG   A CD  1 
ATOM   950  N NE  . ARG   A 1 140 ? 165.195 153.728 169.915 1.00 43.16 ?  140 ARG   A NE  1 
ATOM   951  C CZ  . ARG   A 1 140 ? 165.559 152.821 170.812 1.00 43.16 ?  140 ARG   A CZ  1 
ATOM   952  N NH1 . ARG   A 1 140 ? 165.966 153.169 172.022 1.00 43.16 1  140 ARG   A NH1 1 
ATOM   953  N NH2 . ARG   A 1 140 ? 165.514 151.533 170.487 1.00 43.16 ?  140 ARG   A NH2 1 
ATOM   954  N N   . ALA   A 1 141 ? 165.241 160.467 169.633 1.00 42.27 ?  141 ALA   A N   1 
ATOM   955  C CA  . ALA   A 1 141 ? 165.087 161.867 169.261 1.00 42.27 ?  141 ALA   A CA  1 
ATOM   956  C C   . ALA   A 1 141 ? 166.437 162.565 169.218 1.00 42.27 ?  141 ALA   A C   1 
ATOM   957  O O   . ALA   A 1 141 ? 166.655 163.460 168.395 1.00 42.27 ?  141 ALA   A O   1 
ATOM   958  C CB  . ALA   A 1 141 ? 164.149 162.574 170.237 1.00 42.27 ?  141 ALA   A CB  1 
ATOM   959  N N   . ALA   A 1 142 ? 167.357 162.173 170.100 1.00 41.50 ?  142 ALA   A N   1 
ATOM   960  C CA  . ALA   A 1 142 ? 168.700 162.738 170.053 1.00 41.50 ?  142 ALA   A CA  1 
ATOM   961  C C   . ALA   A 1 142 ? 169.387 162.401 168.739 1.00 41.50 ?  142 ALA   A C   1 
ATOM   962  O O   . ALA   A 1 142 ? 170.040 163.257 168.134 1.00 41.50 ?  142 ALA   A O   1 
ATOM   963  C CB  . ALA   A 1 142 ? 169.526 162.229 171.232 1.00 41.50 ?  142 ALA   A CB  1 
ATOM   964  N N   . ALA   A 1 143 ? 169.252 161.156 168.280 1.00 41.00 ?  143 ALA   A N   1 
ATOM   965  C CA  . ALA   A 1 143 ? 169.838 160.778 166.998 1.00 41.00 ?  143 ALA   A CA  1 
ATOM   966  C C   . ALA   A 1 143 ? 169.208 161.564 165.856 1.00 41.00 ?  143 ALA   A C   1 
ATOM   967  O O   . ALA   A 1 143 ? 169.910 162.029 164.949 1.00 41.00 ?  143 ALA   A O   1 
ATOM   968  C CB  . ALA   A 1 143 ? 169.674 159.277 166.769 1.00 41.00 ?  143 ALA   A CB  1 
ATOM   969  N N   . VAL   A 1 144 ? 167.884 161.723 165.881 1.00 40.97 ?  144 VAL   A N   1 
ATOM   970  C CA  . VAL   A 1 144 ? 167.215 162.489 164.830 1.00 40.97 ?  144 VAL   A CA  1 
ATOM   971  C C   . VAL   A 1 144 ? 167.724 163.925 164.820 1.00 40.97 ?  144 VAL   A C   1 
ATOM   972  O O   . VAL   A 1 144 ? 168.002 164.499 163.761 1.00 40.97 ?  144 VAL   A O   1 
ATOM   973  C CB  . VAL   A 1 144 ? 165.688 162.444 165.015 1.00 40.97 ?  144 VAL   A CB  1 
ATOM   974  C CG1 . VAL   A 1 144 ? 165.014 163.406 164.053 1.00 40.97 ?  144 VAL   A CG1 1 
ATOM   975  C CG2 . VAL   A 1 144 ? 165.170 161.042 164.804 1.00 40.97 ?  144 VAL   A CG2 1 
ATOM   976  N N   . TRP   A 1 145 ? 167.832 164.531 166.003 1.00 41.07 ?  145 TRP   A N   1 
ATOM   977  C CA  . TRP   A 1 145 ? 168.295 165.910 166.088 1.00 41.07 ?  145 TRP   A CA  1 
ATOM   978  C C   . TRP   A 1 145 ? 169.729 166.037 165.603 1.00 41.07 ?  145 TRP   A C   1 
ATOM   979  O O   . TRP   A 1 145 ? 170.077 167.003 164.917 1.00 41.07 ?  145 TRP   A O   1 
ATOM   980  C CB  . TRP   A 1 145 ? 168.170 166.418 167.522 1.00 41.07 ?  145 TRP   A CB  1 
ATOM   981  C CG  . TRP   A 1 145 ? 166.959 167.249 167.734 1.00 41.07 ?  145 TRP   A CG  1 
ATOM   982  C CD1 . TRP   A 1 145 ? 165.789 166.861 168.310 1.00 41.07 ?  145 TRP   A CD1 1 
ATOM   983  C CD2 . TRP   A 1 145 ? 166.790 168.619 167.363 1.00 41.07 ?  145 TRP   A CD2 1 
ATOM   984  N NE1 . TRP   A 1 145 ? 164.900 167.906 168.323 1.00 41.07 ?  145 TRP   A NE1 1 
ATOM   985  C CE2 . TRP   A 1 145 ? 165.492 168.998 167.746 1.00 41.07 ?  145 TRP   A CE2 1 
ATOM   986  C CE3 . TRP   A 1 145 ? 167.612 169.562 166.743 1.00 41.07 ?  145 TRP   A CE3 1 
ATOM   987  C CZ2 . TRP   A 1 145 ? 164.996 170.280 167.532 1.00 41.07 ?  145 TRP   A CZ2 1 
ATOM   988  C CZ3 . TRP   A 1 145 ? 167.120 170.832 166.531 1.00 41.07 ?  145 TRP   A CZ3 1 
ATOM   989  C CH2 . TRP   A 1 145 ? 165.825 171.180 166.924 1.00 41.07 ?  145 TRP   A CH2 1 
ATOM   990  N N   . THR   A 1 146 ? 170.580 165.077 165.958 1.00 40.21 ?  146 THR   A N   1 
ATOM   991  C CA  . THR   A 1 146 ? 171.954 165.111 165.479 1.00 40.21 ?  146 THR   A CA  1 
ATOM   992  C C   . THR   A 1 146 ? 171.998 165.028 163.961 1.00 40.21 ?  146 THR   A C   1 
ATOM   993  O O   . THR   A 1 146 ? 172.736 165.777 163.313 1.00 40.21 ?  146 THR   A O   1 
ATOM   994  C CB  . THR   A 1 146 ? 172.748 163.966 166.100 1.00 40.21 ?  146 THR   A CB  1 
ATOM   995  O OG1 . THR   A 1 146 ? 172.742 164.100 167.525 1.00 40.21 ?  146 THR   A OG1 1 
ATOM   996  C CG2 . THR   A 1 146 ? 174.183 163.973 165.599 1.00 40.21 ?  146 THR   A CG2 1 
ATOM   997  N N   . ALA   A 1 147 ? 171.203 164.133 163.375 1.00 39.96 ?  147 ALA   A N   1 
ATOM   998  C CA  . ALA   A 1 147 ? 171.204 163.993 161.923 1.00 39.96 ?  147 ALA   A CA  1 
ATOM   999  C C   . ALA   A 1 147 ? 170.713 165.263 161.243 1.00 39.96 ?  147 ALA   A C   1 
ATOM   1000 O O   . ALA   A 1 147 ? 171.287 165.696 160.238 1.00 39.96 ?  147 ALA   A O   1 
ATOM   1001 C CB  . ALA   A 1 147 ? 170.339 162.805 161.512 1.00 39.96 ?  147 ALA   A CB  1 
ATOM   1002 N N   . VAL   A 1 148 ? 169.647 165.870 161.769 1.00 40.79 ?  148 VAL   A N   1 
ATOM   1003 C CA  . VAL   A 1 148 ? 169.075 167.050 161.125 1.00 40.79 ?  148 VAL   A CA  1 
ATOM   1004 C C   . VAL   A 1 148 ? 170.003 168.249 161.272 1.00 40.79 ?  148 VAL   A C   1 
ATOM   1005 O O   . VAL   A 1 148 ? 170.242 168.987 160.310 1.00 40.79 ?  148 VAL   A O   1 
ATOM   1006 C CB  . VAL   A 1 148 ? 167.679 167.345 161.699 1.00 40.79 ?  148 VAL   A CB  1 
ATOM   1007 C CG1 . VAL   A 1 148 ? 167.213 168.730 161.281 1.00 40.79 ?  148 VAL   A CG1 1 
ATOM   1008 C CG2 . VAL   A 1 148 ? 166.688 166.288 161.245 1.00 40.79 ?  148 VAL   A CG2 1 
ATOM   1009 N N   . THR   A 1 149 ? 170.537 168.469 162.474 1.00 40.34 ?  149 THR   A N   1 
ATOM   1010 C CA  . THR   A 1 149 ? 171.426 169.595 162.722 1.00 40.34 ?  149 THR   A CA  1 
ATOM   1011 C C   . THR   A 1 149 ? 172.858 169.322 162.294 1.00 40.34 ?  149 THR   A C   1 
ATOM   1012 O O   . THR   A 1 149 ? 173.685 170.239 162.338 1.00 40.34 ?  149 THR   A O   1 
ATOM   1013 C CB  . THR   A 1 149 ? 171.416 169.967 164.205 1.00 40.34 ?  149 THR   A CB  1 
ATOM   1014 O OG1 . THR   A 1 149 ? 171.932 168.877 164.977 1.00 40.34 ?  149 THR   A OG1 1 
ATOM   1015 C CG2 . THR   A 1 149 ? 170.008 170.291 164.663 1.00 40.34 ?  149 THR   A CG2 1 
ATOM   1016 N N   . MET   A 1 150 ? 173.174 168.092 161.891 1.00 40.93 ?  150 MET   A N   1 
ATOM   1017 C CA  . MET   A 1 150 ? 174.517 167.802 161.407 1.00 40.93 ?  150 MET   A CA  1 
ATOM   1018 C C   . MET   A 1 150 ? 174.875 168.692 160.229 1.00 40.93 ?  150 MET   A C   1 
ATOM   1019 O O   . MET   A 1 150 ? 176.045 169.036 160.040 1.00 40.93 ?  150 MET   A O   1 
ATOM   1020 C CB  . MET   A 1 150 ? 174.615 166.338 160.990 1.00 40.93 ?  150 MET   A CB  1 
ATOM   1021 C CG  . MET   A 1 150 ? 175.978 165.923 160.508 1.00 40.93 ?  150 MET   A CG  1 
ATOM   1022 S SD  . MET   A 1 150 ? 176.283 164.227 161.003 1.00 40.93 ?  150 MET   A SD  1 
ATOM   1023 C CE  . MET   A 1 150 ? 176.514 164.469 162.759 1.00 40.93 ?  150 MET   A CE  1 
ATOM   1024 N N   . TRP   A 1 151 ? 173.880 169.071 159.433 1.00 39.85 ?  151 TRP   A N   1 
ATOM   1025 C CA  . TRP   A 1 151 ? 174.084 169.832 158.213 1.00 39.85 ?  151 TRP   A CA  1 
ATOM   1026 C C   . TRP   A 1 151 ? 173.736 171.303 158.371 1.00 39.85 ?  151 TRP   A C   1 
ATOM   1027 O O   . TRP   A 1 151 ? 173.668 172.021 157.370 1.00 39.85 ?  151 TRP   A O   1 
ATOM   1028 C CB  . TRP   A 1 151 ? 173.265 169.214 157.084 1.00 39.85 ?  151 TRP   A CB  1 
ATOM   1029 C CG  . TRP   A 1 151 ? 173.682 167.818 156.783 1.00 39.85 ?  151 TRP   A CG  1 
ATOM   1030 C CD1 . TRP   A 1 151 ? 172.967 166.682 157.008 1.00 39.85 ?  151 TRP   A CD1 1 
ATOM   1031 C CD2 . TRP   A 1 151 ? 174.919 167.406 156.200 1.00 39.85 ?  151 TRP   A CD2 1 
ATOM   1032 N NE1 . TRP   A 1 151 ? 173.683 165.585 156.600 1.00 39.85 ?  151 TRP   A NE1 1 
ATOM   1033 C CE2 . TRP   A 1 151 ? 174.886 166.005 156.099 1.00 39.85 ?  151 TRP   A CE2 1 
ATOM   1034 C CE3 . TRP   A 1 151 ? 176.051 168.088 155.751 1.00 39.85 ?  151 TRP   A CE3 1 
ATOM   1035 C CZ2 . TRP   A 1 151 ? 175.941 165.273 155.569 1.00 39.85 ?  151 TRP   A CZ2 1 
ATOM   1036 C CZ3 . TRP   A 1 151 ? 177.095 167.361 155.224 1.00 39.85 ?  151 TRP   A CZ3 1 
ATOM   1037 C CH2 . TRP   A 1 151 ? 177.035 165.967 155.137 1.00 39.85 ?  151 TRP   A CH2 1 
ATOM   1038 N N   . THR   A 1 152 ? 173.497 171.767 159.593 1.00 41.07 ?  152 THR   A N   1 
ATOM   1039 C CA  . THR   A 1 152 ? 173.409 173.200 159.814 1.00 41.07 ?  152 THR   A CA  1 
ATOM   1040 C C   . THR   A 1 152 ? 174.752 173.839 159.489 1.00 41.07 ?  152 THR   A C   1 
ATOM   1041 O O   . THR   A 1 152 ? 175.813 173.250 159.706 1.00 41.07 ?  152 THR   A O   1 
ATOM   1042 C CB  . THR   A 1 152 ? 173.014 173.510 161.257 1.00 41.07 ?  152 THR   A CB  1 
ATOM   1043 O OG1 . THR   A 1 152 ? 173.828 172.749 162.157 1.00 41.07 ?  152 THR   A OG1 1 
ATOM   1044 C CG2 . THR   A 1 152 ? 171.547 173.187 161.493 1.00 41.07 ?  152 THR   A CG2 1 
ATOM   1045 N N   . GLU   A 1 153 ? 174.700 175.055 158.956 1.00 41.36 ?  153 GLU   A N   1 
ATOM   1046 C CA  . GLU   A 1 153 ? 175.917 175.712 158.486 1.00 41.36 ?  153 GLU   A CA  1 
ATOM   1047 C C   . GLU   A 1 153 ? 177.028 175.719 159.526 1.00 41.36 ?  153 GLU   A C   1 
ATOM   1048 O O   . GLU   A 1 153 ? 178.176 175.414 159.169 1.00 41.36 ?  153 GLU   A O   1 
ATOM   1049 C CB  . GLU   A 1 153 ? 175.569 177.136 158.033 1.00 41.36 ?  153 GLU   A CB  1 
ATOM   1050 C CG  . GLU   A 1 153 ? 176.738 177.912 157.467 1.00 41.36 ?  153 GLU   A CG  1 
ATOM   1051 C CD  . GLU   A 1 153 ? 176.415 179.374 157.302 1.00 41.36 ?  153 GLU   A CD  1 
ATOM   1052 O OE1 . GLU   A 1 153 ? 175.359 179.806 157.809 1.00 41.36 ?  153 GLU   A OE1 1 
ATOM   1053 O OE2 . GLU   A 1 153 ? 177.216 180.091 156.666 1.00 41.36 -1 153 GLU   A OE2 1 
ATOM   1054 N N   . PRO   A 1 154 ? 176.779 176.046 160.795 1.00 40.05 ?  154 PRO   A N   1 
ATOM   1055 C CA  . PRO   A 1 154 ? 177.875 175.990 161.774 1.00 40.05 ?  154 PRO   A CA  1 
ATOM   1056 C C   . PRO   A 1 154 ? 178.470 174.602 161.928 1.00 40.05 ?  154 PRO   A C   1 
ATOM   1057 O O   . PRO   A 1 154 ? 179.697 174.458 161.981 1.00 40.05 ?  154 PRO   A O   1 
ATOM   1058 C CB  . PRO   A 1 154 ? 177.204 176.470 163.068 1.00 40.05 ?  154 PRO   A CB  1 
ATOM   1059 C CG  . PRO   A 1 154 ? 175.994 177.216 162.618 1.00 40.05 ?  154 PRO   A CG  1 
ATOM   1060 C CD  . PRO   A 1 154 ? 175.523 176.497 161.410 1.00 40.05 ?  154 PRO   A CD  1 
ATOM   1061 N N   . VAL   A 1 155 ? 177.630 173.567 161.984 1.00 39.81 ?  155 VAL   A N   1 
ATOM   1062 C CA  . VAL   A 1 155 ? 178.137 172.217 162.205 1.00 39.81 ?  155 VAL   A CA  1 
ATOM   1063 C C   . VAL   A 1 155 ? 178.932 171.736 160.998 1.00 39.81 ?  155 VAL   A C   1 
ATOM   1064 O O   . VAL   A 1 155 ? 180.018 171.162 161.144 1.00 39.81 ?  155 VAL   A O   1 
ATOM   1065 C CB  . VAL   A 1 155 ? 176.978 171.262 162.534 1.00 39.81 ?  155 VAL   A CB  1 
ATOM   1066 C CG1 . VAL   A 1 155 ? 177.486 169.837 162.659 1.00 39.81 ?  155 VAL   A CG1 1 
ATOM   1067 C CG2 . VAL   A 1 155 ? 176.284 171.695 163.813 1.00 39.81 ?  155 VAL   A CG2 1 
ATOM   1068 N N   . ARG   A 1 156 ? 178.404 171.941 159.792 1.00 39.63 ?  156 ARG   A N   1 
ATOM   1069 C CA  . ARG   A 1 156 ? 179.139 171.515 158.609 1.00 39.63 ?  156 ARG   A CA  1 
ATOM   1070 C C   . ARG   A 1 156 ? 180.416 172.322 158.436 1.00 39.63 ?  156 ARG   A C   1 
ATOM   1071 O O   . ARG   A 1 156 ? 181.417 171.793 157.942 1.00 39.63 ?  156 ARG   A O   1 
ATOM   1072 C CB  . ARG   A 1 156 ? 178.259 171.623 157.364 1.00 39.63 ?  156 ARG   A CB  1 
ATOM   1073 C CG  . ARG   A 1 156 ? 177.837 173.033 157.000 1.00 39.63 ?  156 ARG   A CG  1 
ATOM   1074 C CD  . ARG   A 1 156 ? 176.532 173.021 156.220 1.00 39.63 ?  156 ARG   A CD  1 
ATOM   1075 N NE  . ARG   A 1 156 ? 176.327 174.238 155.446 1.00 39.63 ?  156 ARG   A NE  1 
ATOM   1076 C CZ  . ARG   A 1 156 ? 175.239 174.498 154.735 1.00 39.63 ?  156 ARG   A CZ  1 
ATOM   1077 N NH1 . ARG   A 1 156 ? 174.230 173.645 154.677 1.00 39.63 1  156 ARG   A NH1 1 
ATOM   1078 N NH2 . ARG   A 1 156 ? 175.159 175.644 154.067 1.00 39.63 ?  156 ARG   A NH2 1 
ATOM   1079 N N   . SER   A 1 157 ? 180.409 173.594 158.838 1.00 40.04 ?  157 SER   A N   1 
ATOM   1080 C CA  . SER   A 1 157 ? 181.638 174.378 158.794 1.00 40.04 ?  157 SER   A CA  1 
ATOM   1081 C C   . SER   A 1 157 ? 182.675 173.830 159.767 1.00 40.04 ?  157 SER   A C   1 
ATOM   1082 O O   . SER   A 1 157 ? 183.854 173.709 159.418 1.00 40.04 ?  157 SER   A O   1 
ATOM   1083 C CB  . SER   A 1 157 ? 181.334 175.844 159.097 1.00 40.04 ?  157 SER   A CB  1 
ATOM   1084 O OG  . SER   A 1 157 ? 180.442 176.387 158.142 1.00 40.04 ?  157 SER   A OG  1 
ATOM   1085 N N   . THR   A 1 158 ? 182.259 173.485 160.988 1.00 39.76 ?  158 THR   A N   1 
ATOM   1086 C CA  . THR   A 1 158 ? 183.202 172.896 161.934 1.00 39.76 ?  158 THR   A CA  1 
ATOM   1087 C C   . THR   A 1 158 ? 183.761 171.585 161.402 1.00 39.76 ?  158 THR   A C   1 
ATOM   1088 O O   . THR   A 1 158 ? 184.971 171.342 161.473 1.00 39.76 ?  158 THR   A O   1 
ATOM   1089 C CB  . THR   A 1 158 ? 182.535 172.662 163.287 1.00 39.76 ?  158 THR   A CB  1 
ATOM   1090 O OG1 . THR   A 1 158 ? 181.349 171.880 163.111 1.00 39.76 ?  158 THR   A OG1 1 
ATOM   1091 C CG2 . THR   A 1 158 ? 182.180 173.974 163.943 1.00 39.76 ?  158 THR   A CG2 1 
ATOM   1092 N N   . LEU   A 1 159 ? 182.896 170.725 160.864 1.00 39.18 ?  159 LEU   A N   1 
ATOM   1093 C CA  . LEU   A 1 159 ? 183.365 169.443 160.348 1.00 39.18 ?  159 LEU   A CA  1 
ATOM   1094 C C   . LEU   A 1 159 ? 184.328 169.636 159.184 1.00 39.18 ?  159 LEU   A C   1 
ATOM   1095 O O   . LEU   A 1 159 ? 185.356 168.955 159.104 1.00 39.18 ?  159 LEU   A O   1 
ATOM   1096 C CB  . LEU   A 1 159 ? 182.178 168.582 159.924 1.00 39.18 ?  159 LEU   A CB  1 
ATOM   1097 C CG  . LEU   A 1 159 ? 181.470 167.844 161.060 1.00 39.18 ?  159 LEU   A CG  1 
ATOM   1098 C CD1 . LEU   A 1 159 ? 180.051 167.481 160.659 1.00 39.18 ?  159 LEU   A CD1 1 
ATOM   1099 C CD2 . LEU   A 1 159 ? 182.248 166.603 161.457 1.00 39.18 ?  159 LEU   A CD2 1 
ATOM   1100 N N   . ASP   A 1 160 ? 184.002 170.570 158.298 1.00 40.10 ?  160 ASP   A N   1 
ATOM   1101 C CA  . ASP   A 1 160 ? 184.864 170.799 157.116 1.00 40.10 ?  160 ASP   A CA  1 
ATOM   1102 C C   . ASP   A 1 160 ? 186.247 171.215 157.588 1.00 40.10 ?  160 ASP   A C   1 
ATOM   1103 O O   . ASP   A 1 160 ? 187.222 170.547 157.213 1.00 40.10 ?  160 ASP   A O   1 
ATOM   1104 C CB  . ASP   A 1 160 ? 184.383 171.957 156.239 1.00 40.10 ?  160 ASP   A CB  1 
ATOM   1105 C CG  . ASP   A 1 160 ? 182.991 171.838 155.649 1.00 40.10 ?  160 ASP   A CG  1 
ATOM   1106 O OD1 . ASP   A 1 160 ? 182.639 170.744 155.190 1.00 40.10 ?  160 ASP   A OD1 1 
ATOM   1107 O OD2 . ASP   A 1 160 ? 182.282 172.862 155.628 1.00 40.10 -1 160 ASP   A OD2 1 
ATOM   1108 N N   . TYR   A 1 161 ? 186.319 172.273 158.389 1.00 40.71 ?  161 TYR   A N   1 
ATOM   1109 C CA  . TYR   A 1 161 ? 187.599 172.847 158.780 1.00 40.71 ?  161 TYR   A CA  1 
ATOM   1110 C C   . TYR   A 1 161 ? 188.288 172.060 159.884 1.00 40.71 ?  161 TYR   A C   1 
ATOM   1111 O O   . TYR   A 1 161 ? 189.481 172.270 160.120 1.00 40.71 ?  161 TYR   A O   1 
ATOM   1112 C CB  . TYR   A 1 161 ? 187.408 174.296 159.232 1.00 40.71 ?  161 TYR   A CB  1 
ATOM   1113 C CG  . TYR   A 1 161 ? 186.990 175.235 158.124 1.00 40.71 ?  161 TYR   A CG  1 
ATOM   1114 C CD1 . TYR   A 1 161 ? 187.911 175.700 157.199 1.00 40.71 ?  161 TYR   A CD1 1 
ATOM   1115 C CD2 . TYR   A 1 161 ? 185.678 175.662 158.008 1.00 40.71 ?  161 TYR   A CD2 1 
ATOM   1116 C CE1 . TYR   A 1 161 ? 187.536 176.557 156.187 1.00 40.71 ?  161 TYR   A CE1 1 
ATOM   1117 C CE2 . TYR   A 1 161 ? 185.293 176.520 157.000 1.00 40.71 ?  161 TYR   A CE2 1 
ATOM   1118 C CZ  . TYR   A 1 161 ? 186.226 176.964 156.093 1.00 40.71 ?  161 TYR   A CZ  1 
ATOM   1119 O OH  . TYR   A 1 161 ? 185.847 177.821 155.086 1.00 40.71 ?  161 TYR   A OH  1 
ATOM   1120 N N   . GLY   A 1 162 ? 187.577 171.162 160.560 1.00 40.21 ?  162 GLY   A N   1 
ATOM   1121 C CA  . GLY   A 1 162 ? 188.145 170.452 161.686 1.00 40.21 ?  162 GLY   A CA  1 
ATOM   1122 C C   . GLY   A 1 162 ? 188.232 171.264 162.955 1.00 40.21 ?  162 GLY   A C   1 
ATOM   1123 O O   . GLY   A 1 162 ? 188.806 170.789 163.940 1.00 40.21 ?  162 GLY   A O   1 
ATOM   1124 N N   . GLN   A 1 163 ? 187.679 172.472 162.962 1.00 40.60 ?  163 GLN   A N   1 
ATOM   1125 C CA  . GLN   A 1 163 ? 187.746 173.332 164.132 1.00 40.60 ?  163 GLN   A CA  1 
ATOM   1126 C C   . GLN   A 1 163 ? 187.031 172.670 165.305 1.00 40.60 ?  163 GLN   A C   1 
ATOM   1127 O O   . GLN   A 1 163 ? 186.004 172.010 165.132 1.00 40.60 ?  163 GLN   A O   1 
ATOM   1128 C CB  . GLN   A 1 163 ? 187.118 174.687 163.799 1.00 40.60 ?  163 GLN   A CB  1 
ATOM   1129 C CG  . GLN   A 1 163 ? 186.956 175.664 164.957 1.00 40.60 ?  163 GLN   A CG  1 
ATOM   1130 C CD  . GLN   A 1 163 ? 188.122 176.625 165.082 1.00 40.60 ?  163 GLN   A CD  1 
ATOM   1131 O OE1 . GLN   A 1 163 ? 188.985 176.695 164.208 1.00 40.60 ?  163 GLN   A OE1 1 
ATOM   1132 N NE2 . GLN   A 1 163 ? 188.135 177.393 166.163 1.00 40.60 ?  163 GLN   A NE2 1 
ATOM   1133 N N   . ILE   A 1 164 ? 187.586 172.839 166.504 1.00 40.62 ?  164 ILE   A N   1 
ATOM   1134 C CA  . ILE   A 1 164 ? 187.019 172.233 167.713 1.00 40.62 ?  164 ILE   A CA  1 
ATOM   1135 C C   . ILE   A 1 164 ? 186.024 173.235 168.290 1.00 40.62 ?  164 ILE   A C   1 
ATOM   1136 O O   . ILE   A 1 164 ? 186.361 174.077 169.123 1.00 40.62 ?  164 ILE   A O   1 
ATOM   1137 C CB  . ILE   A 1 164 ? 188.093 171.840 168.725 1.00 40.62 ?  164 ILE   A CB  1 
ATOM   1138 C CG1 . ILE   A 1 164 ? 189.124 172.957 168.900 1.00 40.62 ?  164 ILE   A CG1 1 
ATOM   1139 C CG2 . ILE   A 1 164 ? 188.774 170.559 168.297 1.00 40.62 ?  164 ILE   A CG2 1 
ATOM   1140 C CD1 . ILE   A 1 164 ? 189.990 172.780 170.123 1.00 40.62 ?  164 ILE   A CD1 1 
ATOM   1141 N N   . ASN   A 1 165 ? 184.779 173.136 167.841 1.00 40.22 ?  165 ASN   A N   1 
ATOM   1142 C CA  . ASN   A 1 165 ? 183.680 173.892 168.421 1.00 40.22 ?  165 ASN   A CA  1 
ATOM   1143 C C   . ASN   A 1 165 ? 182.591 173.008 169.001 1.00 40.22 ?  165 ASN   A C   1 
ATOM   1144 O O   . ASN   A 1 165 ? 181.969 173.393 169.993 1.00 40.22 ?  165 ASN   A O   1 
ATOM   1145 C CB  . ASN   A 1 165 ? 183.054 174.822 167.372 1.00 40.22 ?  165 ASN   A CB  1 
ATOM   1146 C CG  . ASN   A 1 165 ? 184.061 175.774 166.756 1.00 40.22 ?  165 ASN   A CG  1 
ATOM   1147 O OD1 . ASN   A 1 165 ? 183.935 176.150 165.593 1.00 40.22 ?  165 ASN   A OD1 1 
ATOM   1148 N ND2 . ASN   A 1 165 ? 185.062 176.174 167.532 1.00 40.22 ?  165 ASN   A ND2 1 
ATOM   1149 N N   . VAL   A 1 166 ? 182.340 171.840 168.410 1.00 40.73 ?  166 VAL   A N   1 
ATOM   1150 C CA  . VAL   A 1 166 ? 181.393 170.905 169.004 1.00 40.73 ?  166 VAL   A CA  1 
ATOM   1151 C C   . VAL   A 1 166 ? 181.965 170.318 170.287 1.00 40.73 ?  166 VAL   A C   1 
ATOM   1152 O O   . VAL   A 1 166 ? 181.235 170.091 171.257 1.00 40.73 ?  166 VAL   A O   1 
ATOM   1153 C CB  . VAL   A 1 166 ? 181.020 169.802 167.998 1.00 40.73 ?  166 VAL   A CB  1 
ATOM   1154 C CG1 . VAL   A 1 166 ? 179.847 168.992 168.522 1.00 40.73 ?  166 VAL   A CG1 1 
ATOM   1155 C CG2 . VAL   A 1 166 ? 180.690 170.405 166.642 1.00 40.73 ?  166 VAL   A CG2 1 
ATOM   1156 N N   . LEU   A 1 167 ? 183.273 170.051 170.312 1.00 40.90 ?  167 LEU   A N   1 
ATOM   1157 C CA  . LEU   A 1 167 ? 183.885 169.491 171.513 1.00 40.90 ?  167 LEU   A CA  1 
ATOM   1158 C C   . LEU   A 1 167 ? 183.787 170.456 172.687 1.00 40.90 ?  167 LEU   A C   1 
ATOM   1159 O O   . LEU   A 1 167 ? 183.451 170.052 173.805 1.00 40.90 ?  167 LEU   A O   1 
ATOM   1160 C CB  . LEU   A 1 167 ? 185.344 169.130 171.242 1.00 40.90 ?  167 LEU   A CB  1 
ATOM   1161 C CG  . LEU   A 1 167 ? 185.574 167.795 170.534 1.00 40.90 ?  167 LEU   A CG  1 
ATOM   1162 C CD1 . LEU   A 1 167 ? 185.205 167.889 169.064 1.00 40.90 ?  167 LEU   A CD1 1 
ATOM   1163 C CD2 . LEU   A 1 167 ? 187.015 167.347 170.702 1.00 40.90 ?  167 LEU   A CD2 1 
ATOM   1164 N N   . LEU   A 1 168 ? 184.076 171.738 172.457 1.00 40.00 ?  168 LEU   A N   1 
ATOM   1165 C CA  . LEU   A 1 168 ? 183.989 172.701 173.548 1.00 40.00 ?  168 LEU   A CA  1 
ATOM   1166 C C   . LEU   A 1 168 ? 182.543 172.955 173.952 1.00 40.00 ?  168 LEU   A C   1 
ATOM   1167 O O   . LEU   A 1 168 ? 182.266 173.193 175.132 1.00 40.00 ?  168 LEU   A O   1 
ATOM   1168 C CB  . LEU   A 1 168 ? 184.676 174.008 173.156 1.00 40.00 ?  168 LEU   A CB  1 
ATOM   1169 C CG  . LEU   A 1 168 ? 186.177 173.920 172.858 1.00 40.00 ?  168 LEU   A CG  1 
ATOM   1170 C CD1 . LEU   A 1 168 ? 186.814 175.290 172.980 1.00 40.00 ?  168 LEU   A CD1 1 
ATOM   1171 C CD2 . LEU   A 1 168 ? 186.886 172.927 173.766 1.00 40.00 ?  168 LEU   A CD2 1 
ATOM   1172 N N   . MET   A 1 169 ? 181.610 172.900 173.001 1.00 39.70 ?  169 MET   A N   1 
ATOM   1173 C CA  . MET   A 1 169 ? 180.198 172.960 173.360 1.00 39.70 ?  169 MET   A CA  1 
ATOM   1174 C C   . MET   A 1 169 ? 179.822 171.792 174.261 1.00 39.70 ?  169 MET   A C   1 
ATOM   1175 O O   . MET   A 1 169 ? 179.098 171.962 175.251 1.00 39.70 ?  169 MET   A O   1 
ATOM   1176 C CB  . MET   A 1 169 ? 179.340 172.956 172.095 1.00 39.70 ?  169 MET   A CB  1 
ATOM   1177 C CG  . MET   A 1 169 ? 177.892 173.337 172.327 1.00 39.70 ?  169 MET   A CG  1 
ATOM   1178 S SD  . MET   A 1 169 ? 177.008 173.697 170.801 1.00 39.70 ?  169 MET   A SD  1 
ATOM   1179 C CE  . MET   A 1 169 ? 176.430 172.066 170.348 1.00 39.70 ?  169 MET   A CE  1 
ATOM   1180 N N   . LEU   A 1 170 ? 180.306 170.594 173.929 1.00 39.89 ?  170 LEU   A N   1 
ATOM   1181 C CA  . LEU   A 1 170 ? 180.049 169.429 174.764 1.00 39.89 ?  170 LEU   A CA  1 
ATOM   1182 C C   . LEU   A 1 170 ? 180.629 169.626 176.155 1.00 39.89 ?  170 LEU   A C   1 
ATOM   1183 O O   . LEU   A 1 170 ? 179.978 169.314 177.155 1.00 39.89 ?  170 LEU   A O   1 
ATOM   1184 C CB  . LEU   A 1 170 ? 180.644 168.182 174.109 1.00 39.89 ?  170 LEU   A CB  1 
ATOM   1185 C CG  . LEU   A 1 170 ? 180.869 166.954 174.993 1.00 39.89 ?  170 LEU   A CG  1 
ATOM   1186 C CD1 . LEU   A 1 170 ? 179.599 166.560 175.732 1.00 39.89 ?  170 LEU   A CD1 1 
ATOM   1187 C CD2 . LEU   A 1 170 ? 181.384 165.793 174.164 1.00 39.89 ?  170 LEU   A CD2 1 
ATOM   1188 N N   . LEU   A 1 171 ? 181.852 170.148 176.240 1.00 39.50 ?  171 LEU   A N   1 
ATOM   1189 C CA  . LEU   A 1 171 ? 182.464 170.380 177.545 1.00 39.50 ?  171 LEU   A CA  1 
ATOM   1190 C C   . LEU   A 1 171 ? 181.654 171.382 178.357 1.00 39.50 ?  171 LEU   A C   1 
ATOM   1191 O O   . LEU   A 1 171 ? 181.434 171.194 179.559 1.00 39.50 ?  171 LEU   A O   1 
ATOM   1192 C CB  . LEU   A 1 171 ? 183.903 170.869 177.375 1.00 39.50 ?  171 LEU   A CB  1 
ATOM   1193 C CG  . LEU   A 1 171 ? 184.906 169.910 176.732 1.00 39.50 ?  171 LEU   A CG  1 
ATOM   1194 C CD1 . LEU   A 1 171 ? 186.313 170.450 176.894 1.00 39.50 ?  171 LEU   A CD1 1 
ATOM   1195 C CD2 . LEU   A 1 171 ? 184.804 168.517 177.326 1.00 39.50 ?  171 LEU   A CD2 1 
ATOM   1196 N N   . ILE   A 1 172 ? 181.197 172.457 177.715 1.00 39.76 ?  172 ILE   A N   1 
ATOM   1197 C CA  . ILE   A 1 172 ? 180.470 173.492 178.442 1.00 39.76 ?  172 ILE   A CA  1 
ATOM   1198 C C   . ILE   A 1 172 ? 179.128 172.965 178.935 1.00 39.76 ?  172 ILE   A C   1 
ATOM   1199 O O   . ILE   A 1 172 ? 178.729 173.223 180.077 1.00 39.76 ?  172 ILE   A O   1 
ATOM   1200 C CB  . ILE   A 1 172 ? 180.309 174.742 177.561 1.00 39.76 ?  172 ILE   A CB  1 
ATOM   1201 C CG1 . ILE   A 1 172 ? 181.657 175.451 177.430 1.00 39.76 ?  172 ILE   A CG1 1 
ATOM   1202 C CG2 . ILE   A 1 172 ? 179.268 175.675 178.154 1.00 39.76 ?  172 ILE   A CG2 1 
ATOM   1203 C CD1 . ILE   A 1 172 ? 181.711 176.483 176.334 1.00 39.76 ?  172 ILE   A CD1 1 
ATOM   1204 N N   . LEU   A 1 173 ? 178.405 172.218 178.096 1.00 40.22 ?  173 LEU   A N   1 
ATOM   1205 C CA  . LEU   A 1 173 ? 177.130 171.676 178.557 1.00 40.22 ?  173 LEU   A CA  1 
ATOM   1206 C C   . LEU   A 1 173 ? 177.325 170.548 179.562 1.00 40.22 ?  173 LEU   A C   1 
ATOM   1207 O O   . LEU   A 1 173 ? 176.453 170.323 180.407 1.00 40.22 ?  173 LEU   A O   1 
ATOM   1208 C CB  . LEU   A 1 173 ? 176.279 171.203 177.378 1.00 40.22 ?  173 LEU   A CB  1 
ATOM   1209 C CG  . LEU   A 1 173 ? 175.503 172.318 176.668 1.00 40.22 ?  173 LEU   A CG  1 
ATOM   1210 C CD1 . LEU   A 1 173 ? 174.801 171.795 175.434 1.00 40.22 ?  173 LEU   A CD1 1 
ATOM   1211 C CD2 . LEU   A 1 173 ? 174.497 172.982 177.603 1.00 40.22 ?  173 LEU   A CD2 1 
ATOM   1212 N N   . LEU   A 1 174 ? 178.451 169.835 179.502 1.00 40.01 ?  174 LEU   A N   1 
ATOM   1213 C CA  . LEU   A 1 174 ? 178.772 168.888 180.561 1.00 40.01 ?  174 LEU   A CA  1 
ATOM   1214 C C   . LEU   A 1 174 ? 178.992 169.614 181.878 1.00 40.01 ?  174 LEU   A C   1 
ATOM   1215 O O   . LEU   A 1 174 ? 178.562 169.146 182.937 1.00 40.01 ?  174 LEU   A O   1 
ATOM   1216 C CB  . LEU   A 1 174 ? 180.011 168.078 180.186 1.00 40.01 ?  174 LEU   A CB  1 
ATOM   1217 C CG  . LEU   A 1 174 ? 179.779 166.841 179.321 1.00 40.01 ?  174 LEU   A CG  1 
ATOM   1218 C CD1 . LEU   A 1 174 ? 181.100 166.323 178.783 1.00 40.01 ?  174 LEU   A CD1 1 
ATOM   1219 C CD2 . LEU   A 1 174 ? 179.062 165.757 180.107 1.00 40.01 ?  174 LEU   A CD2 1 
ATOM   1220 N N   . ALA   A 1 175 ? 179.671 170.760 181.830 1.00 39.60 ?  175 ALA   A N   1 
ATOM   1221 C CA  . ALA   A 1 175 ? 179.844 171.559 183.035 1.00 39.60 ?  175 ALA   A CA  1 
ATOM   1222 C C   . ALA   A 1 175 ? 178.502 172.038 183.568 1.00 39.60 ?  175 ALA   A C   1 
ATOM   1223 O O   . ALA   A 1 175 ? 178.250 171.992 184.777 1.00 39.60 ?  175 ALA   A O   1 
ATOM   1224 C CB  . ALA   A 1 175 ? 180.759 172.746 182.747 1.00 39.60 ?  175 ALA   A CB  1 
ATOM   1225 N N   . VAL   A 1 176 ? 177.625 172.499 182.676 1.00 40.45 ?  176 VAL   A N   1 
ATOM   1226 C CA  . VAL   A 1 176 ? 176.319 172.993 183.109 1.00 40.45 ?  176 VAL   A CA  1 
ATOM   1227 C C   . VAL   A 1 176 ? 175.500 171.867 183.730 1.00 40.45 ?  176 VAL   A C   1 
ATOM   1228 O O   . VAL   A 1 176 ? 174.857 172.049 184.770 1.00 40.45 ?  176 VAL   A O   1 
ATOM   1229 C CB  . VAL   A 1 176 ? 175.576 173.647 181.930 1.00 40.45 ?  176 VAL   A CB  1 
ATOM   1230 C CG1 . VAL   A 1 176 ? 174.124 173.910 182.296 1.00 40.45 ?  176 VAL   A CG1 1 
ATOM   1231 C CG2 . VAL   A 1 176 ? 176.266 174.938 181.521 1.00 40.45 ?  176 VAL   A CG2 1 
ATOM   1232 N N   . ALA   A 1 177 ? 175.507 170.690 183.102 1.00 40.67 ?  177 ALA   A N   1 
ATOM   1233 C CA  . ALA   A 1 177 ? 174.708 169.578 183.605 1.00 40.67 ?  177 ALA   A CA  1 
ATOM   1234 C C   . ALA   A 1 177 ? 175.165 169.147 184.991 1.00 40.67 ?  177 ALA   A C   1 
ATOM   1235 O O   . ALA   A 1 177 ? 174.339 168.879 185.871 1.00 40.67 ?  177 ALA   A O   1 
ATOM   1236 C CB  . ALA   A 1 177 ? 174.778 168.402 182.632 1.00 40.67 ?  177 ALA   A CB  1 
ATOM   1237 N N   . SER   A 1 178 ? 176.475 169.072 185.207 1.00 40.92 ?  178 SER   A N   1 
ATOM   1238 C CA  . SER   A 1 178 ? 176.994 168.630 186.492 1.00 40.92 ?  178 SER   A CA  1 
ATOM   1239 C C   . SER   A 1 178 ? 176.839 169.732 187.529 1.00 40.92 ?  178 SER   A C   1 
ATOM   1240 O O   . SER   A 1 178 ? 177.381 170.830 187.372 1.00 40.92 ?  178 SER   A O   1 
ATOM   1241 C CB  . SER   A 1 178 ? 178.461 168.232 186.362 1.00 40.92 ?  178 SER   A CB  1 
ATOM   1242 O OG  . SER   A 1 178 ? 178.653 167.350 185.270 1.00 40.92 ?  178 SER   A OG  1 
ATOM   1243 N N   . SER   A 1 179 ? 176.092 169.436 188.593 1.00 41.77 ?  179 SER   A N   1 
ATOM   1244 C CA  . SER   A 1 179 ? 175.929 170.392 189.680 1.00 41.77 ?  179 SER   A CA  1 
ATOM   1245 C C   . SER   A 1 179 ? 177.185 170.496 190.531 1.00 41.77 ?  179 SER   A C   1 
ATOM   1246 O O   . SER   A 1 179 ? 177.369 171.493 191.237 1.00 41.77 ?  179 SER   A O   1 
ATOM   1247 C CB  . SER   A 1 179 ? 174.742 169.993 190.557 1.00 41.77 ?  179 SER   A CB  1 
ATOM   1248 O OG  . SER   A 1 179 ? 174.999 168.777 191.237 1.00 41.77 ?  179 SER   A OG  1 
ATOM   1249 N N   . ARG   A 1 180 ? 178.048 169.486 190.479 1.00 41.16 ?  180 ARG   A N   1 
ATOM   1250 C CA  . ARG   A 1 180 ? 179.262 169.483 191.282 1.00 41.16 ?  180 ARG   A CA  1 
ATOM   1251 C C   . ARG   A 1 180 ? 180.146 170.659 190.896 1.00 41.16 ?  180 ARG   A C   1 
ATOM   1252 O O   . ARG   A 1 180 ? 180.454 170.858 189.718 1.00 41.16 ?  180 ARG   A O   1 
ATOM   1253 C CB  . ARG   A 1 180 ? 180.014 168.163 191.097 1.00 41.16 ?  180 ARG   A CB  1 
ATOM   1254 C CG  . ARG   A 1 180 ? 179.198 166.906 191.409 1.00 41.16 ?  180 ARG   A CG  1 
ATOM   1255 C CD  . ARG   A 1 180 ? 178.478 166.342 190.181 1.00 41.16 ?  180 ARG   A CD  1 
ATOM   1256 N NE  . ARG   A 1 180 ? 177.892 165.033 190.445 1.00 41.16 ?  180 ARG   A NE  1 
ATOM   1257 C CZ  . ARG   A 1 180 ? 177.224 164.315 189.552 1.00 41.16 ?  180 ARG   A CZ  1 
ATOM   1258 N NH1 . ARG   A 1 180 ? 177.073 164.729 188.305 1.00 41.16 1  180 ARG   A NH1 1 
ATOM   1259 N NH2 . ARG   A 1 180 ? 176.702 163.148 189.918 1.00 41.16 ?  180 ARG   A NH2 1 
ATOM   1260 N N   . TRP   A 1 181 ? 180.557 171.439 191.897 1.00 39.83 ?  181 TRP   A N   1 
ATOM   1261 C CA  . TRP   A 1 181 ? 181.267 172.681 191.612 1.00 39.83 ?  181 TRP   A CA  1 
ATOM   1262 C C   . TRP   A 1 181 ? 182.608 172.417 190.936 1.00 39.83 ?  181 TRP   A C   1 
ATOM   1263 O O   . TRP   A 1 181 ? 182.958 173.089 189.959 1.00 39.83 ?  181 TRP   A O   1 
ATOM   1264 C CB  . TRP   A 1 181 ? 181.459 173.485 192.900 1.00 39.83 ?  181 TRP   A CB  1 
ATOM   1265 C CG  . TRP   A 1 181 ? 182.479 172.916 193.843 1.00 39.83 ?  181 TRP   A CG  1 
ATOM   1266 C CD1 . TRP   A 1 181 ? 182.248 172.081 194.895 1.00 39.83 ?  181 TRP   A CD1 1 
ATOM   1267 C CD2 . TRP   A 1 181 ? 183.891 173.152 193.821 1.00 39.83 ?  181 TRP   A CD2 1 
ATOM   1268 N NE1 . TRP   A 1 181 ? 183.429 171.778 195.527 1.00 39.83 ?  181 TRP   A NE1 1 
ATOM   1269 C CE2 . TRP   A 1 181 ? 184.453 172.424 194.885 1.00 39.83 ?  181 TRP   A CE2 1 
ATOM   1270 C CE3 . TRP   A 1 181 ? 184.734 173.905 193.002 1.00 39.83 ?  181 TRP   A CE3 1 
ATOM   1271 C CZ2 . TRP   A 1 181 ? 185.818 172.427 195.152 1.00 39.83 ?  181 TRP   A CZ2 1 
ATOM   1272 C CZ3 . TRP   A 1 181 ? 186.087 173.908 193.269 1.00 39.83 ?  181 TRP   A CZ3 1 
ATOM   1273 C CH2 . TRP   A 1 181 ? 186.616 173.174 194.334 1.00 39.83 ?  181 TRP   A CH2 1 
ATOM   1274 N N   . TRP   A 1 182 ? 183.370 171.440 191.430 1.00 39.27 ?  182 TRP   A N   1 
ATOM   1275 C CA  . TRP   A 1 182 ? 184.710 171.227 190.896 1.00 39.27 ?  182 TRP   A CA  1 
ATOM   1276 C C   . TRP   A 1 182 ? 184.652 170.726 189.458 1.00 39.27 ?  182 TRP   A C   1 
ATOM   1277 O O   . TRP   A 1 182 ? 185.424 171.174 188.604 1.00 39.27 ?  182 TRP   A O   1 
ATOM   1278 C CB  . TRP   A 1 182 ? 185.495 170.264 191.791 1.00 39.27 ?  182 TRP   A CB  1 
ATOM   1279 C CG  . TRP   A 1 182 ? 185.038 168.839 191.768 1.00 39.27 ?  182 TRP   A CG  1 
ATOM   1280 C CD1 . TRP   A 1 182 ? 185.572 167.823 191.034 1.00 39.27 ?  182 TRP   A CD1 1 
ATOM   1281 C CD2 . TRP   A 1 182 ? 183.988 168.258 192.550 1.00 39.27 ?  182 TRP   A CD2 1 
ATOM   1282 N NE1 . TRP   A 1 182 ? 184.907 166.650 191.292 1.00 39.27 ?  182 TRP   A NE1 1 
ATOM   1283 C CE2 . TRP   A 1 182 ? 183.929 166.890 192.220 1.00 39.27 ?  182 TRP   A CE2 1 
ATOM   1284 C CE3 . TRP   A 1 182 ? 183.085 168.764 193.489 1.00 39.27 ?  182 TRP   A CE3 1 
ATOM   1285 C CZ2 . TRP   A 1 182 ? 183.002 166.023 192.793 1.00 39.27 ?  182 TRP   A CZ2 1 
ATOM   1286 C CZ3 . TRP   A 1 182 ? 182.165 167.901 194.057 1.00 39.27 ?  182 TRP   A CZ3 1 
ATOM   1287 C CH2 . TRP   A 1 182 ? 182.130 166.546 193.707 1.00 39.27 ?  182 TRP   A CH2 1 
ATOM   1288 N N   . ILE   A 1 183 ? 183.723 169.815 189.163 1.00 39.84 ?  183 ILE   A N   1 
ATOM   1289 C CA  . ILE   A 1 183 ? 183.626 169.273 187.811 1.00 39.84 ?  183 ILE   A CA  1 
ATOM   1290 C C   . ILE   A 1 183 ? 183.303 170.383 186.818 1.00 39.84 ?  183 ILE   A C   1 
ATOM   1291 O O   . ILE   A 1 183 ? 183.990 170.554 185.803 1.00 39.84 ?  183 ILE   A O   1 
ATOM   1292 C CB  . ILE   A 1 183 ? 182.574 168.150 187.760 1.00 39.84 ?  183 ILE   A CB  1 
ATOM   1293 C CG1 . ILE   A 1 183 ? 183.119 166.886 188.424 1.00 39.84 ?  183 ILE   A CG1 1 
ATOM   1294 C CG2 . ILE   A 1 183 ? 182.182 167.844 186.325 1.00 39.84 ?  183 ILE   A CG2 1 
ATOM   1295 C CD1 . ILE   A 1 183 ? 182.058 165.874 188.788 1.00 39.84 ?  183 ILE   A CD1 1 
ATOM   1296 N N   . SER   A 1 184 ? 182.261 171.165 187.104 1.00 39.57 ?  184 SER   A N   1 
ATOM   1297 C CA  . SER   A 1 184 ? 181.859 172.216 186.176 1.00 39.57 ?  184 SER   A CA  1 
ATOM   1298 C C   . SER   A 1 184 ? 182.946 173.271 186.038 1.00 39.57 ?  184 SER   A C   1 
ATOM   1299 O O   . SER   A 1 184 ? 183.257 173.715 184.925 1.00 39.57 ?  184 SER   A O   1 
ATOM   1300 C CB  . SER   A 1 184 ? 180.551 172.852 186.642 1.00 39.57 ?  184 SER   A CB  1 
ATOM   1301 O OG  . SER   A 1 184 ? 179.454 171.991 186.398 1.00 39.57 ?  184 SER   A OG  1 
ATOM   1302 N N   . GLY   A 1 185 ? 183.538 173.684 187.159 1.00 39.22 ?  185 GLY   A N   1 
ATOM   1303 C CA  . GLY   A 1 185 ? 184.591 174.682 187.094 1.00 39.22 ?  185 GLY   A CA  1 
ATOM   1304 C C   . GLY   A 1 185 ? 185.766 174.220 186.256 1.00 39.22 ?  185 GLY   A C   1 
ATOM   1305 O O   . GLY   A 1 185 ? 186.264 174.959 185.404 1.00 39.22 ?  185 GLY   A O   1 
ATOM   1306 N N   . THR   A 1 186 ? 186.222 172.986 186.484 1.00 38.01 ?  186 THR   A N   1 
ATOM   1307 C CA  . THR   A 1 186 ? 187.367 172.477 185.740 1.00 38.01 ?  186 THR   A CA  1 
ATOM   1308 C C   . THR   A 1 186 ? 187.050 172.348 184.258 1.00 38.01 ?  186 THR   A C   1 
ATOM   1309 O O   . THR   A 1 186 ? 187.877 172.700 183.408 1.00 38.01 ?  186 THR   A O   1 
ATOM   1310 C CB  . THR   A 1 186 ? 187.807 171.132 186.313 1.00 38.01 ?  186 THR   A CB  1 
ATOM   1311 O OG1 . THR   A 1 186 ? 187.793 171.193 187.744 1.00 38.01 ?  186 THR   A OG1 1 
ATOM   1312 C CG2 . THR   A 1 186 ? 189.205 170.786 185.840 1.00 38.01 ?  186 THR   A CG2 1 
ATOM   1313 N N   . LEU   A 1 187 ? 185.863 171.838 183.921 1.00 38.53 ?  187 LEU   A N   1 
ATOM   1314 C CA  . LEU   A 1 187 ? 185.496 171.730 182.513 1.00 38.53 ?  187 LEU   A CA  1 
ATOM   1315 C C   . LEU   A 1 187 ? 185.499 173.096 181.842 1.00 38.53 ?  187 LEU   A C   1 
ATOM   1316 O O   . LEU   A 1 187 ? 186.090 173.272 180.769 1.00 38.53 ?  187 LEU   A O   1 
ATOM   1317 C CB  . LEU   A 1 187 ? 184.129 171.058 182.366 1.00 38.53 ?  187 LEU   A CB  1 
ATOM   1318 C CG  . LEU   A 1 187 ? 184.082 169.527 182.331 1.00 38.53 ?  187 LEU   A CG  1 
ATOM   1319 C CD1 . LEU   A 1 187 ? 184.801 169.011 181.096 1.00 38.53 ?  187 LEU   A CD1 1 
ATOM   1320 C CD2 . LEU   A 1 187 ? 184.670 168.887 183.575 1.00 38.53 ?  187 LEU   A CD2 1 
ATOM   1321 N N   . ILE   A 1 188 ? 184.850 174.083 182.463 1.00 38.90 ?  188 ILE   A N   1 
ATOM   1322 C CA  . ILE   A 1 188 ? 184.787 175.406 181.851 1.00 38.90 ?  188 ILE   A CA  1 
ATOM   1323 C C   . ILE   A 1 188 ? 186.184 175.992 181.713 1.00 38.90 ?  188 ILE   A C   1 
ATOM   1324 O O   . ILE   A 1 188 ? 186.533 176.559 180.672 1.00 38.90 ?  188 ILE   A O   1 
ATOM   1325 C CB  . ILE   A 1 188 ? 183.865 176.334 182.662 1.00 38.90 ?  188 ILE   A CB  1 
ATOM   1326 C CG1 . ILE   A 1 188 ? 182.432 175.799 182.668 1.00 38.90 ?  188 ILE   A CG1 1 
ATOM   1327 C CG2 . ILE   A 1 188 ? 183.906 177.746 182.097 1.00 38.90 ?  188 ILE   A CG2 1 
ATOM   1328 C CD1 . ILE   A 1 188 ? 181.768 175.765 181.305 1.00 38.90 ?  188 ILE   A CD1 1 
ATOM   1329 N N   . GLY   A 1 189 ? 187.006 175.864 182.755 1.00 38.85 ?  189 GLY   A N   1 
ATOM   1330 C CA  . GLY   A 1 189 ? 188.338 176.440 182.704 1.00 38.85 ?  189 GLY   A CA  1 
ATOM   1331 C C   . GLY   A 1 189 ? 189.202 175.824 181.622 1.00 38.85 ?  189 GLY   A C   1 
ATOM   1332 O O   . GLY   A 1 189 ? 189.860 176.536 180.863 1.00 38.85 ?  189 GLY   A O   1 
ATOM   1333 N N   . LEU   A 1 190 ? 189.214 174.494 181.532 1.00 39.22 ?  190 LEU   A N   1 
ATOM   1334 C CA  . LEU   A 1 190 ? 190.009 173.841 180.498 1.00 39.22 ?  190 LEU   A CA  1 
ATOM   1335 C C   . LEU   A 1 190 ? 189.504 174.203 179.105 1.00 39.22 ?  190 LEU   A C   1 
ATOM   1336 O O   . LEU   A 1 190 ? 190.298 174.541 178.214 1.00 39.22 ?  190 LEU   A O   1 
ATOM   1337 C CB  . LEU   A 1 190 ? 189.983 172.328 180.703 1.00 39.22 ?  190 LEU   A CB  1 
ATOM   1338 C CG  . LEU   A 1 190 ? 190.910 171.513 179.801 1.00 39.22 ?  190 LEU   A CG  1 
ATOM   1339 C CD1 . LEU   A 1 190 ? 191.622 170.435 180.603 1.00 39.22 ?  190 LEU   A CD1 1 
ATOM   1340 C CD2 . LEU   A 1 190 ? 190.130 170.898 178.649 1.00 39.22 ?  190 LEU   A CD2 1 
ATOM   1341 N N   . ALA   A 1 191 ? 188.184 174.159 178.901 1.00 39.76 ?  191 ALA   A N   1 
ATOM   1342 C CA  . ALA   A 1 191 ? 187.639 174.468 177.585 1.00 39.76 ?  191 ALA   A CA  1 
ATOM   1343 C C   . ALA   A 1 191 ? 187.968 175.896 177.178 1.00 39.76 ?  191 ALA   A C   1 
ATOM   1344 O O   . ALA   A 1 191 ? 188.301 176.157 176.017 1.00 39.76 ?  191 ALA   A O   1 
ATOM   1345 C CB  . ALA   A 1 191 ? 186.128 174.240 177.579 1.00 39.76 ?  191 ALA   A CB  1 
ATOM   1346 N N   . GLY   A 1 192 ? 187.880 176.839 178.118 1.00 40.29 ?  192 GLY   A N   1 
ATOM   1347 C CA  . GLY   A 1 192 ? 188.260 178.208 177.827 1.00 40.29 ?  192 GLY   A CA  1 
ATOM   1348 C C   . GLY   A 1 192 ? 189.748 178.402 177.644 1.00 40.29 ?  192 GLY   A C   1 
ATOM   1349 O O   . GLY   A 1 192 ? 190.163 179.327 176.939 1.00 40.29 ?  192 GLY   A O   1 
ATOM   1350 N N   . GLY   A 1 193 ? 190.564 177.562 178.279 1.00 40.52 ?  193 GLY   A N   1 
ATOM   1351 C CA  . GLY   A 1 193 ? 191.990 177.609 178.024 1.00 40.52 ?  193 GLY   A CA  1 
ATOM   1352 C C   . GLY   A 1 193 ? 192.326 177.183 176.610 1.00 40.52 ?  193 GLY   A C   1 
ATOM   1353 O O   . GLY   A 1 193 ? 193.210 177.759 175.972 1.00 40.52 ?  193 GLY   A O   1 
ATOM   1354 N N   . VAL   A 1 194 ? 191.626 176.170 176.100 1.00 41.03 ?  194 VAL   A N   1 
ATOM   1355 C CA  . VAL   A 1 194 ? 191.858 175.741 174.724 1.00 41.03 ?  194 VAL   A CA  1 
ATOM   1356 C C   . VAL   A 1 194 ? 191.509 176.862 173.754 1.00 41.03 ?  194 VAL   A C   1 
ATOM   1357 O O   . VAL   A 1 194 ? 192.258 177.146 172.813 1.00 41.03 ?  194 VAL   A O   1 
ATOM   1358 C CB  . VAL   A 1 194 ? 191.061 174.463 174.418 1.00 41.03 ?  194 VAL   A CB  1 
ATOM   1359 C CG1 . VAL   A 1 194 ? 191.220 174.081 172.959 1.00 41.03 ?  194 VAL   A CG1 1 
ATOM   1360 C CG2 . VAL   A 1 194 ? 191.519 173.331 175.314 1.00 41.03 ?  194 VAL   A CG2 1 
ATOM   1361 N N   . LYS   A 1 195 ? 190.364 177.509 173.963 1.00 41.25 ?  195 LYS   A N   1 
ATOM   1362 C CA  . LYS   A 1 195 ? 189.939 178.652 173.163 1.00 41.25 ?  195 LYS   A CA  1 
ATOM   1363 C C   . LYS   A 1 195 ? 189.352 179.697 174.095 1.00 41.25 ?  195 LYS   A C   1 
ATOM   1364 O O   . LYS   A 1 195 ? 188.617 179.353 175.024 1.00 41.25 ?  195 LYS   A O   1 
ATOM   1365 C CB  . LYS   A 1 195 ? 188.894 178.250 172.116 1.00 41.25 ?  195 LYS   A CB  1 
ATOM   1366 C CG  . LYS   A 1 195 ? 189.430 177.412 170.976 1.00 41.25 ?  195 LYS   A CG  1 
ATOM   1367 C CD  . LYS   A 1 195 ? 188.288 176.863 170.130 1.00 41.25 ?  195 LYS   A CD  1 
ATOM   1368 C CE  . LYS   A 1 195 ? 187.542 177.950 169.371 1.00 41.25 ?  195 LYS   A CE  1 
ATOM   1369 N NZ  . LYS   A 1 195 ? 188.434 179.003 168.816 1.00 41.25 1  195 LYS   A NZ  1 
ATOM   1370 N N   . LEU   A 1 196 ? 189.662 180.968 173.846 1.00 41.64 ?  196 LEU   A N   1 
ATOM   1371 C CA  . LEU   A 1 196 ? 189.156 182.023 174.714 1.00 41.64 ?  196 LEU   A CA  1 
ATOM   1372 C C   . LEU   A 1 196 ? 187.700 182.376 174.444 1.00 41.64 ?  196 LEU   A C   1 
ATOM   1373 O O   . LEU   A 1 196 ? 187.060 182.974 175.315 1.00 41.64 ?  196 LEU   A O   1 
ATOM   1374 C CB  . LEU   A 1 196 ? 190.008 183.281 174.570 1.00 41.64 ?  196 LEU   A CB  1 
ATOM   1375 C CG  . LEU   A 1 196 ? 191.465 183.187 175.019 1.00 41.64 ?  196 LEU   A CG  1 
ATOM   1376 C CD1 . LEU   A 1 196 ? 192.156 184.510 174.757 1.00 41.64 ?  196 LEU   A CD1 1 
ATOM   1377 C CD2 . LEU   A 1 196 ? 191.560 182.813 176.487 1.00 41.64 ?  196 LEU   A CD2 1 
ATOM   1378 N N   . THR   A 1 197 ? 187.164 182.039 173.270 1.00 41.59 ?  197 THR   A N   1 
ATOM   1379 C CA  . THR   A 1 197 ? 185.783 182.409 172.961 1.00 41.59 ?  197 THR   A CA  1 
ATOM   1380 C C   . THR   A 1 197 ? 184.779 181.774 173.914 1.00 41.59 ?  197 THR   A C   1 
ATOM   1381 O O   . THR   A 1 197 ? 183.871 182.480 174.386 1.00 41.59 ?  197 THR   A O   1 
ATOM   1382 C CB  . THR   A 1 197 ? 185.478 182.074 171.498 1.00 41.59 ?  197 THR   A CB  1 
ATOM   1383 O OG1 . THR   A 1 197 ? 185.802 180.706 171.229 1.00 41.59 ?  197 THR   A OG1 1 
ATOM   1384 C CG2 . THR   A 1 197 ? 186.273 182.978 170.564 1.00 41.59 ?  197 THR   A CG2 1 
ATOM   1385 N N   . PRO   A 1 198 ? 184.866 180.474 174.245 1.00 41.03 ?  198 PRO   A N   1 
ATOM   1386 C CA  . PRO   A 1 198 ? 183.852 179.888 175.134 1.00 41.03 ?  198 PRO   A CA  1 
ATOM   1387 C C   . PRO   A 1 198 ? 183.893 180.409 176.563 1.00 41.03 ?  198 PRO   A C   1 
ATOM   1388 O O   . PRO   A 1 198 ? 183.026 180.055 177.368 1.00 41.03 ?  198 PRO   A O   1 
ATOM   1389 C CB  . PRO   A 1 198 ? 184.169 178.389 175.079 1.00 41.03 ?  198 PRO   A CB  1 
ATOM   1390 C CG  . PRO   A 1 198 ? 185.596 178.323 174.728 1.00 41.03 ?  198 PRO   A CG  1 
ATOM   1391 C CD  . PRO   A 1 198 ? 185.802 179.445 173.762 1.00 41.03 ?  198 PRO   A CD  1 
ATOM   1392 N N   . LEU   A 1 199 ? 184.874 181.243 176.901 1.00 40.63 ?  199 LEU   A N   1 
ATOM   1393 C CA  . LEU   A 1 199 ? 184.909 181.846 178.228 1.00 40.63 ?  199 LEU   A CA  1 
ATOM   1394 C C   . LEU   A 1 199 ? 183.649 182.634 178.553 1.00 40.63 ?  199 LEU   A C   1 
ATOM   1395 O O   . LEU   A 1 199 ? 183.297 182.745 179.732 1.00 40.63 ?  199 LEU   A O   1 
ATOM   1396 C CB  . LEU   A 1 199 ? 186.125 182.765 178.370 1.00 40.63 ?  199 LEU   A CB  1 
ATOM   1397 C CG  . LEU   A 1 199 ? 187.500 182.105 178.337 1.00 40.63 ?  199 LEU   A CG  1 
ATOM   1398 C CD1 . LEU   A 1 199 ? 188.586 183.162 178.345 1.00 40.63 ?  199 LEU   A CD1 1 
ATOM   1399 C CD2 . LEU   A 1 199 ? 187.664 181.179 179.529 1.00 40.63 ?  199 LEU   A CD2 1 
ATOM   1400 N N   . VAL   A 1 200 ? 182.958 183.177 177.548 1.00 41.87 ?  200 VAL   A N   1 
ATOM   1401 C CA  . VAL   A 1 200 ? 181.700 183.873 177.805 1.00 41.87 ?  200 VAL   A CA  1 
ATOM   1402 C C   . VAL   A 1 200 ? 180.678 182.973 178.473 1.00 41.87 ?  200 VAL   A C   1 
ATOM   1403 O O   . VAL   A 1 200 ? 179.794 183.474 179.179 1.00 41.87 ?  200 VAL   A O   1 
ATOM   1404 C CB  . VAL   A 1 200 ? 181.106 184.437 176.501 1.00 41.87 ?  200 VAL   A CB  1 
ATOM   1405 C CG1 . VAL   A 1 200 ? 180.715 183.308 175.559 1.00 41.87 ?  200 VAL   A CG1 1 
ATOM   1406 C CG2 . VAL   A 1 200 ? 179.911 185.331 176.804 1.00 41.87 ?  200 VAL   A CG2 1 
ATOM   1407 N N   . SER   A 1 201 ? 180.774 181.655 178.276 1.00 40.98 ?  201 SER   A N   1 
ATOM   1408 C CA  . SER   A 1 201 ? 179.871 180.743 178.967 1.00 40.98 ?  201 SER   A CA  1 
ATOM   1409 C C   . SER   A 1 201 ? 179.964 180.910 180.474 1.00 40.98 ?  201 SER   A C   1 
ATOM   1410 O O   . SER   A 1 201 ? 178.964 180.732 181.178 1.00 40.98 ?  201 SER   A O   1 
ATOM   1411 C CB  . SER   A 1 201 ? 180.184 179.300 178.582 1.00 40.98 ?  201 SER   A CB  1 
ATOM   1412 O OG  . SER   A 1 201 ? 179.923 179.081 177.211 1.00 40.98 ?  201 SER   A OG  1 
ATOM   1413 N N   . GLY   A 1 202 ? 181.144 181.261 180.985 1.00 41.43 ?  202 GLY   A N   1 
ATOM   1414 C CA  . GLY   A 1 202 ? 181.275 181.493 182.411 1.00 41.43 ?  202 GLY   A CA  1 
ATOM   1415 C C   . GLY   A 1 202 ? 180.292 182.523 182.922 1.00 41.43 ?  202 GLY   A C   1 
ATOM   1416 O O   . GLY   A 1 202 ? 179.838 182.441 184.066 1.00 41.43 ?  202 GLY   A O   1 
ATOM   1417 N N   . LEU   A 1 203 ? 179.932 183.495 182.080 1.00 40.66 ?  203 LEU   A N   1 
ATOM   1418 C CA  . LEU   A 1 203 ? 178.970 184.507 182.496 1.00 40.66 ?  203 LEU   A CA  1 
ATOM   1419 C C   . LEU   A 1 203 ? 177.660 183.873 182.935 1.00 40.66 ?  203 LEU   A C   1 
ATOM   1420 O O   . LEU   A 1 203 ? 177.032 184.346 183.889 1.00 40.66 ?  203 LEU   A O   1 
ATOM   1421 C CB  . LEU   A 1 203 ? 178.727 185.500 181.361 1.00 40.66 ?  203 LEU   A CB  1 
ATOM   1422 C CG  . LEU   A 1 203 ? 178.076 186.818 181.777 1.00 40.66 ?  203 LEU   A CG  1 
ATOM   1423 C CD1 . LEU   A 1 203 ? 178.554 187.945 180.879 1.00 40.66 ?  203 LEU   A CD1 1 
ATOM   1424 C CD2 . LEU   A 1 203 ? 176.559 186.720 181.750 1.00 40.66 ?  203 LEU   A CD2 1 
ATOM   1425 N N   . TYR   A 1 204 ? 177.235 182.798 182.268 1.00 40.95 ?  204 TYR   A N   1 
ATOM   1426 C CA  . TYR   A 1 204 ? 176.018 182.117 182.693 1.00 40.95 ?  204 TYR   A CA  1 
ATOM   1427 C C   . TYR   A 1 204 ? 176.127 181.676 184.144 1.00 40.95 ?  204 TYR   A C   1 
ATOM   1428 O O   . TYR   A 1 204 ? 175.180 181.832 184.924 1.00 40.95 ?  204 TYR   A O   1 
ATOM   1429 C CB  . TYR   A 1 204 ? 175.736 180.912 181.799 1.00 40.95 ?  204 TYR   A CB  1 
ATOM   1430 C CG  . TYR   A 1 204 ? 174.983 179.811 182.508 1.00 40.95 ?  204 TYR   A CG  1 
ATOM   1431 C CD1 . TYR   A 1 204 ? 173.661 179.984 182.889 1.00 40.95 ?  204 TYR   A CD1 1 
ATOM   1432 C CD2 . TYR   A 1 204 ? 175.596 178.604 182.805 1.00 40.95 ?  204 TYR   A CD2 1 
ATOM   1433 C CE1 . TYR   A 1 204 ? 172.970 178.984 183.539 1.00 40.95 ?  204 TYR   A CE1 1 
ATOM   1434 C CE2 . TYR   A 1 204 ? 174.912 177.598 183.454 1.00 40.95 ?  204 TYR   A CE2 1 
ATOM   1435 C CZ  . TYR   A 1 204 ? 173.600 177.794 183.819 1.00 40.95 ?  204 TYR   A CZ  1 
ATOM   1436 O OH  . TYR   A 1 204 ? 172.915 176.794 184.468 1.00 40.95 ?  204 TYR   A OH  1 
ATOM   1437 N N   . PHE   A 1 205 ? 177.280 181.127 184.528 1.00 40.76 ?  205 PHE   A N   1 
ATOM   1438 C CA  . PHE   A 1 205 ? 177.468 180.731 185.916 1.00 40.76 ?  205 PHE   A CA  1 
ATOM   1439 C C   . PHE   A 1 205 ? 177.388 181.934 186.844 1.00 40.76 ?  205 PHE   A C   1 
ATOM   1440 O O   . PHE   A 1 205 ? 176.898 181.815 187.972 1.00 40.76 ?  205 PHE   A O   1 
ATOM   1441 C CB  . PHE   A 1 205 ? 178.802 180.007 186.070 1.00 40.76 ?  205 PHE   A CB  1 
ATOM   1442 C CG  . PHE   A 1 205 ? 178.871 178.716 185.312 1.00 40.76 ?  205 PHE   A CG  1 
ATOM   1443 C CD1 . PHE   A 1 205 ? 178.468 177.531 185.899 1.00 40.76 ?  205 PHE   A CD1 1 
ATOM   1444 C CD2 . PHE   A 1 205 ? 179.322 178.690 184.007 1.00 40.76 ?  205 PHE   A CD2 1 
ATOM   1445 C CE1 . PHE   A 1 205 ? 178.524 176.344 185.200 1.00 40.76 ?  205 PHE   A CE1 1 
ATOM   1446 C CE2 . PHE   A 1 205 ? 179.379 177.505 183.303 1.00 40.76 ?  205 PHE   A CE2 1 
ATOM   1447 C CZ  . PHE   A 1 205 ? 178.980 176.332 183.900 1.00 40.76 ?  205 PHE   A CZ  1 
ATOM   1448 N N   . LEU   A 1 206 ? 177.853 183.098 186.391 1.00 41.29 ?  206 LEU   A N   1 
ATOM   1449 C CA  . LEU   A 1 206 ? 177.638 184.314 187.164 1.00 41.29 ?  206 LEU   A CA  1 
ATOM   1450 C C   . LEU   A 1 206 ? 176.151 184.610 187.294 1.00 41.29 ?  206 LEU   A C   1 
ATOM   1451 O O   . LEU   A 1 206 ? 175.680 185.000 188.368 1.00 41.29 ?  206 LEU   A O   1 
ATOM   1452 C CB  . LEU   A 1 206 ? 178.369 185.486 186.510 1.00 41.29 ?  206 LEU   A CB  1 
ATOM   1453 C CG  . LEU   A 1 206 ? 178.404 186.810 187.279 1.00 41.29 ?  206 LEU   A CG  1 
ATOM   1454 C CD1 . LEU   A 1 206 ? 179.633 187.607 186.877 1.00 41.29 ?  206 LEU   A CD1 1 
ATOM   1455 C CD2 . LEU   A 1 206 ? 177.142 187.634 187.047 1.00 41.29 ?  206 LEU   A CD2 1 
ATOM   1456 N N   . GLY   A 1 207 ? 175.396 184.427 186.210 1.00 42.25 ?  207 GLY   A N   1 
ATOM   1457 C CA  . GLY   A 1 207 ? 173.956 184.610 186.282 1.00 42.25 ?  207 GLY   A CA  1 
ATOM   1458 C C   . GLY   A 1 207 ? 173.281 183.569 187.154 1.00 42.25 ?  207 GLY   A C   1 
ATOM   1459 O O   . GLY   A 1 207 ? 172.297 183.864 187.838 1.00 42.25 ?  207 GLY   A O   1 
ATOM   1460 N N   . ALA   A 1 208 ? 173.792 182.340 187.140 1.00 42.22 ?  208 ALA   A N   1 
ATOM   1461 C CA  . ALA   A 1 208 ? 173.251 181.261 187.956 1.00 42.22 ?  208 ALA   A CA  1 
ATOM   1462 C C   . ALA   A 1 208 ? 173.664 181.363 189.418 1.00 42.22 ?  208 ALA   A C   1 
ATOM   1463 O O   . ALA   A 1 208 ? 173.357 180.456 190.198 1.00 42.22 ?  208 ALA   A O   1 
ATOM   1464 C CB  . ALA   A 1 208 ? 173.690 179.907 187.395 1.00 42.22 ?  208 ALA   A CB  1 
ATOM   1465 N N   . ARG   A 1 209 ? 174.354 182.435 189.803 1.00 43.14 ?  209 ARG   A N   1 
ATOM   1466 C CA  . ARG   A 1 209 ? 174.788 182.655 191.179 1.00 43.14 ?  209 ARG   A CA  1 
ATOM   1467 C C   . ARG   A 1 209 ? 175.772 181.591 191.650 1.00 43.14 ?  209 ARG   A C   1 
ATOM   1468 O O   . ARG   A 1 209 ? 176.003 181.446 192.854 1.00 43.14 ?  209 ARG   A O   1 
ATOM   1469 C CB  . ARG   A 1 209 ? 173.590 182.719 192.132 1.00 43.14 ?  209 ARG   A CB  1 
ATOM   1470 C CG  . ARG   A 1 209 ? 172.419 183.541 191.610 1.00 43.14 ?  209 ARG   A CG  1 
ATOM   1471 C CD  . ARG   A 1 209 ? 172.799 185.000 191.421 1.00 43.14 ?  209 ARG   A CD  1 
ATOM   1472 N NE  . ARG   A 1 209 ? 171.645 185.885 191.543 1.00 43.14 ?  209 ARG   A NE  1 
ATOM   1473 C CZ  . ARG   A 1 209 ? 171.457 186.990 190.833 1.00 43.14 ?  209 ARG   A CZ  1 
ATOM   1474 N NH1 . ARG   A 1 209 ? 172.337 187.397 189.932 1.00 43.14 1  209 ARG   A NH1 1 
ATOM   1475 N NH2 . ARG   A 1 209 ? 170.356 187.710 191.034 1.00 43.14 ?  209 ARG   A NH2 1 
ATOM   1476 N N   . ARG   A 1 210 ? 176.363 180.839 190.720 1.00 40.65 ?  210 ARG   A N   1 
ATOM   1477 C CA  . ARG   A 1 210 ? 177.354 179.818 191.061 1.00 40.65 ?  210 ARG   A CA  1 
ATOM   1478 C C   . ARG   A 1 210 ? 178.717 180.495 191.147 1.00 40.65 ?  210 ARG   A C   1 
ATOM   1479 O O   . ARG   A 1 210 ? 179.595 180.321 190.301 1.00 40.65 ?  210 ARG   A O   1 
ATOM   1480 C CB  . ARG   A 1 210 ? 177.346 178.693 190.035 1.00 40.65 ?  210 ARG   A CB  1 
ATOM   1481 C CG  . ARG   A 1 210 ? 175.970 178.123 189.749 1.00 40.65 ?  210 ARG   A CG  1 
ATOM   1482 C CD  . ARG   A 1 210 ? 175.990 177.219 188.531 1.00 40.65 ?  210 ARG   A CD  1 
ATOM   1483 N NE  . ARG   A 1 210 ? 176.915 176.104 188.694 1.00 40.65 ?  210 ARG   A NE  1 
ATOM   1484 C CZ  . ARG   A 1 210 ? 176.769 174.914 188.126 1.00 40.65 ?  210 ARG   A CZ  1 
ATOM   1485 N NH1 . ARG   A 1 210 ? 175.746 174.645 187.332 1.00 40.65 1  210 ARG   A NH1 1 
ATOM   1486 N NH2 . ARG   A 1 210 ? 177.675 173.969 188.360 1.00 40.65 ?  210 ARG   A NH2 1 
ATOM   1487 N N   . TRP   A 1 211 ? 178.887 181.291 192.203 1.00 41.15 ?  211 TRP   A N   1 
ATOM   1488 C CA  . TRP   A 1 211 ? 180.119 182.056 192.358 1.00 41.15 ?  211 TRP   A CA  1 
ATOM   1489 C C   . TRP   A 1 211 ? 181.327 181.142 192.537 1.00 41.15 ?  211 TRP   A C   1 
ATOM   1490 O O   . TRP   A 1 211 ? 182.387 181.391 191.952 1.00 41.15 ?  211 TRP   A O   1 
ATOM   1491 C CB  . TRP   A 1 211 ? 179.991 183.013 193.540 1.00 41.15 ?  211 TRP   A CB  1 
ATOM   1492 C CG  . TRP   A 1 211 ? 178.908 184.029 193.366 1.00 41.15 ?  211 TRP   A CG  1 
ATOM   1493 C CD1 . TRP   A 1 211 ? 177.669 184.010 193.933 1.00 41.15 ?  211 TRP   A CD1 1 
ATOM   1494 C CD2 . TRP   A 1 211 ? 178.965 185.216 192.568 1.00 41.15 ?  211 TRP   A CD2 1 
ATOM   1495 N NE1 . TRP   A 1 211 ? 176.950 185.111 193.540 1.00 41.15 ?  211 TRP   A NE1 1 
ATOM   1496 C CE2 . TRP   A 1 211 ? 177.724 185.868 192.702 1.00 41.15 ?  211 TRP   A CE2 1 
ATOM   1497 C CE3 . TRP   A 1 211 ? 179.946 185.791 191.755 1.00 41.15 ?  211 TRP   A CE3 1 
ATOM   1498 C CZ2 . TRP   A 1 211 ? 177.436 187.068 192.051 1.00 41.15 ?  211 TRP   A CZ2 1 
ATOM   1499 C CZ3 . TRP   A 1 211 ? 179.659 186.984 191.110 1.00 41.15 ?  211 TRP   A CZ3 1 
ATOM   1500 C CH2 . TRP   A 1 211 ? 178.414 187.608 191.262 1.00 41.15 ?  211 TRP   A CH2 1 
ATOM   1501 N N   . THR   A 1 212 ? 181.195 180.087 193.345 1.00 38.96 ?  212 THR   A N   1 
ATOM   1502 C CA  . THR   A 1 212 ? 182.334 179.202 193.584 1.00 38.96 ?  212 THR   A CA  1 
ATOM   1503 C C   . THR   A 1 212 ? 182.759 178.486 192.308 1.00 38.96 ?  212 THR   A C   1 
ATOM   1504 O O   . THR   A 1 212 ? 183.958 178.366 192.026 1.00 38.96 ?  212 THR   A O   1 
ATOM   1505 C CB  . THR   A 1 212 ? 182.000 178.187 194.678 1.00 38.96 ?  212 THR   A CB  1 
ATOM   1506 O OG1 . THR   A 1 212 ? 183.142 177.360 194.927 1.00 38.96 ?  212 THR   A OG1 1 
ATOM   1507 C CG2 . THR   A 1 212 ? 180.828 177.305 194.268 1.00 38.96 ?  212 THR   A CG2 1 
ATOM   1508 N N   . THR   A 1 213 ? 181.795 178.001 191.525 1.00 39.13 ?  213 THR   A N   1 
ATOM   1509 C CA  . THR   A 1 213 ? 182.136 177.326 190.278 1.00 39.13 ?  213 THR   A CA  1 
ATOM   1510 C C   . THR   A 1 213 ? 182.800 178.284 189.300 1.00 39.13 ?  213 THR   A C   1 
ATOM   1511 O O   . THR   A 1 213 ? 183.757 177.914 188.613 1.00 39.13 ?  213 THR   A O   1 
ATOM   1512 C CB  . THR   A 1 213 ? 180.886 176.709 189.655 1.00 39.13 ?  213 THR   A CB  1 
ATOM   1513 O OG1 . THR   A 1 213 ? 180.504 175.550 190.403 1.00 39.13 ?  213 THR   A OG1 1 
ATOM   1514 C CG2 . THR   A 1 213 ? 181.148 176.313 188.209 1.00 39.13 ?  213 THR   A CG2 1 
ATOM   1515 N N   . ALA   A 1 214 ? 182.301 179.518 189.214 1.00 39.39 ?  214 ALA   A N   1 
ATOM   1516 C CA  . ALA   A 1 214 ? 182.929 180.502 188.338 1.00 39.39 ?  214 ALA   A CA  1 
ATOM   1517 C C   . ALA   A 1 214 ? 184.349 180.809 188.791 1.00 39.39 ?  214 ALA   A C   1 
ATOM   1518 O O   . ALA   A 1 214 ? 185.261 180.937 187.965 1.00 39.39 ?  214 ALA   A O   1 
ATOM   1519 C CB  . ALA   A 1 214 ? 182.093 181.779 188.298 1.00 39.39 ?  214 ALA   A CB  1 
ATOM   1520 N N   . ILE   A 1 215 ? 184.557 180.934 190.102 1.00 38.82 ?  215 ILE   A N   1 
ATOM   1521 C CA  . ILE   A 1 215 ? 185.894 181.208 190.614 1.00 38.82 ?  215 ILE   A CA  1 
ATOM   1522 C C   . ILE   A 1 215 ? 186.836 180.067 190.263 1.00 38.82 ?  215 ILE   A C   1 
ATOM   1523 O O   . ILE   A 1 215 ? 187.972 180.290 189.829 1.00 38.82 ?  215 ILE   A O   1 
ATOM   1524 C CB  . ILE   A 1 215 ? 185.846 181.453 192.133 1.00 38.82 ?  215 ILE   A CB  1 
ATOM   1525 C CG1 . ILE   A 1 215 ? 185.110 182.756 192.442 1.00 38.82 ?  215 ILE   A CG1 1 
ATOM   1526 C CG2 . ILE   A 1 215 ? 187.252 181.499 192.710 1.00 38.82 ?  215 ILE   A CG2 1 
ATOM   1527 C CD1 . ILE   A 1 215 ? 184.532 182.807 193.839 1.00 38.82 ?  215 ILE   A CD1 1 
ATOM   1528 N N   . TRP   A 1 216 ? 186.386 178.825 190.449 1.00 38.67 ?  216 TRP   A N   1 
ATOM   1529 C CA  . TRP   A 1 216 ? 187.246 177.690 190.132 1.00 38.67 ?  216 TRP   A CA  1 
ATOM   1530 C C   . TRP   A 1 216 ? 187.524 177.605 188.638 1.00 38.67 ?  216 TRP   A C   1 
ATOM   1531 O O   . TRP   A 1 216 ? 188.636 177.255 188.230 1.00 38.67 ?  216 TRP   A O   1 
ATOM   1532 C CB  . TRP   A 1 216 ? 186.622 176.389 190.628 1.00 38.67 ?  216 TRP   A CB  1 
ATOM   1533 C CG  . TRP   A 1 216 ? 187.496 175.202 190.378 1.00 38.67 ?  216 TRP   A CG  1 
ATOM   1534 C CD1 . TRP   A 1 216 ? 187.167 174.075 189.692 1.00 38.67 ?  216 TRP   A CD1 1 
ATOM   1535 C CD2 . TRP   A 1 216 ? 188.852 175.031 190.804 1.00 38.67 ?  216 TRP   A CD2 1 
ATOM   1536 N NE1 . TRP   A 1 216 ? 188.230 173.208 189.668 1.00 38.67 ?  216 TRP   A NE1 1 
ATOM   1537 C CE2 . TRP   A 1 216 ? 189.277 173.773 190.345 1.00 38.67 ?  216 TRP   A CE2 1 
ATOM   1538 C CE3 . TRP   A 1 216 ? 189.746 175.819 191.533 1.00 38.67 ?  216 TRP   A CE3 1 
ATOM   1539 C CZ2 . TRP   A 1 216 ? 190.554 173.284 190.589 1.00 38.67 ?  216 TRP   A CZ2 1 
ATOM   1540 C CZ3 . TRP   A 1 216 ? 191.013 175.331 191.774 1.00 38.67 ?  216 TRP   A CZ3 1 
ATOM   1541 C CH2 . TRP   A 1 216 ? 191.406 174.076 191.304 1.00 38.67 ?  216 TRP   A CH2 1 
ATOM   1542 N N   . ALA   A 1 217 ? 186.529 177.909 187.803 1.00 38.58 ?  217 ALA   A N   1 
ATOM   1543 C CA  . ALA   A 1 217 ? 186.759 177.912 186.363 1.00 38.58 ?  217 ALA   A CA  1 
ATOM   1544 C C   . ALA   A 1 217 ? 187.792 178.963 185.977 1.00 38.58 ?  217 ALA   A C   1 
ATOM   1545 O O   . ALA   A 1 217 ? 188.676 178.704 185.152 1.00 38.58 ?  217 ALA   A O   1 
ATOM   1546 C CB  . ALA   A 1 217 ? 185.446 178.154 185.622 1.00 38.58 ?  217 ALA   A CB  1 
ATOM   1547 N N   . GLY   A 1 218 ? 187.698 180.157 186.564 1.00 38.12 ?  218 GLY   A N   1 
ATOM   1548 C CA  . GLY   A 1 218 ? 188.709 181.171 186.308 1.00 38.12 ?  218 GLY   A CA  1 
ATOM   1549 C C   . GLY   A 1 218 ? 190.087 180.738 186.770 1.00 38.12 ?  218 GLY   A C   1 
ATOM   1550 O O   . GLY   A 1 218 ? 191.089 180.981 186.090 1.00 38.12 ?  218 GLY   A O   1 
ATOM   1551 N N   . VAL   A 1 219 ? 190.157 180.090 187.934 1.00 38.44 ?  219 VAL   A N   1 
ATOM   1552 C CA  . VAL   A 1 219 ? 191.440 179.611 188.440 1.00 38.44 ?  219 VAL   A CA  1 
ATOM   1553 C C   . VAL   A 1 219 ? 192.029 178.580 187.490 1.00 38.44 ?  219 VAL   A C   1 
ATOM   1554 O O   . VAL   A 1 219 ? 193.238 178.566 187.236 1.00 38.44 ?  219 VAL   A O   1 
ATOM   1555 C CB  . VAL   A 1 219 ? 191.275 179.041 189.861 1.00 38.44 ?  219 VAL   A CB  1 
ATOM   1556 C CG1 . VAL   A 1 219 ? 192.490 178.211 190.246 1.00 38.44 ?  219 VAL   A CG1 1 
ATOM   1557 C CG2 . VAL   A 1 219 ? 191.054 180.164 190.859 1.00 38.44 ?  219 VAL   A CG2 1 
ATOM   1558 N N   . VAL   A 1 220 ? 191.189 177.689 186.963 1.00 38.74 ?  220 VAL   A N   1 
ATOM   1559 C CA  . VAL   A 1 220 ? 191.685 176.685 186.032 1.00 38.74 ?  220 VAL   A CA  1 
ATOM   1560 C C   . VAL   A 1 220 ? 192.131 177.338 184.734 1.00 38.74 ?  220 VAL   A C   1 
ATOM   1561 O O   . VAL   A 1 220 ? 193.112 176.903 184.121 1.00 38.74 ?  220 VAL   A O   1 
ATOM   1562 C CB  . VAL   A 1 220 ? 190.621 175.602 185.785 1.00 38.74 ?  220 VAL   A CB  1 
ATOM   1563 C CG1 . VAL   A 1 220 ? 190.971 174.780 184.554 1.00 38.74 ?  220 VAL   A CG1 1 
ATOM   1564 C CG2 . VAL   A 1 220 ? 190.504 174.702 187.000 1.00 38.74 ?  220 VAL   A CG2 1 
ATOM   1565 N N   . PHE   A 1 221 ? 191.430 178.377 184.281 1.00 39.42 ?  221 PHE   A N   1 
ATOM   1566 C CA  . PHE   A 1 221 ? 191.887 179.084 183.091 1.00 39.42 ?  221 PHE   A CA  1 
ATOM   1567 C C   . PHE   A 1 221 ? 193.252 179.718 183.321 1.00 39.42 ?  221 PHE   A C   1 
ATOM   1568 O O   . PHE   A 1 221 ? 194.126 179.648 182.449 1.00 39.42 ?  221 PHE   A O   1 
ATOM   1569 C CB  . PHE   A 1 221 ? 190.872 180.149 182.681 1.00 39.42 ?  221 PHE   A CB  1 
ATOM   1570 C CG  . PHE   A 1 221 ? 191.383 181.104 181.639 1.00 39.42 ?  221 PHE   A CG  1 
ATOM   1571 C CD1 . PHE   A 1 221 ? 191.847 180.636 180.422 1.00 39.42 ?  221 PHE   A CD1 1 
ATOM   1572 C CD2 . PHE   A 1 221 ? 191.397 182.469 181.874 1.00 39.42 ?  221 PHE   A CD2 1 
ATOM   1573 C CE1 . PHE   A 1 221 ? 192.317 181.510 179.461 1.00 39.42 ?  221 PHE   A CE1 1 
ATOM   1574 C CE2 . PHE   A 1 221 ? 191.866 183.347 180.916 1.00 39.42 ?  221 PHE   A CE2 1 
ATOM   1575 C CZ  . PHE   A 1 221 ? 192.326 182.867 179.709 1.00 39.42 ?  221 PHE   A CZ  1 
ATOM   1576 N N   . LEU   A 1 222 ? 193.457 180.329 184.487 1.00 38.96 ?  222 LEU   A N   1 
ATOM   1577 C CA  . LEU   A 1 222 ? 194.760 180.891 184.818 1.00 38.96 ?  222 LEU   A CA  1 
ATOM   1578 C C   . LEU   A 1 222 ? 195.844 179.826 184.918 1.00 38.96 ?  222 LEU   A C   1 
ATOM   1579 O O   . LEU   A 1 222 ? 196.970 180.063 184.470 1.00 38.96 ?  222 LEU   A O   1 
ATOM   1580 C CB  . LEU   A 1 222 ? 194.684 181.672 186.131 1.00 38.96 ?  222 LEU   A CB  1 
ATOM   1581 C CG  . LEU   A 1 222 ? 194.393 183.173 186.015 1.00 38.96 ?  222 LEU   A CG  1 
ATOM   1582 C CD1 . LEU   A 1 222 ? 195.526 183.897 185.304 1.00 38.96 ?  222 LEU   A CD1 1 
ATOM   1583 C CD2 . LEU   A 1 222 ? 193.072 183.423 185.302 1.00 38.96 ?  222 LEU   A CD2 1 
ATOM   1584 N N   . LEU   A 1 223 ? 195.537 178.661 185.487 1.00 38.86 ?  223 LEU   A N   1 
ATOM   1585 C CA  . LEU   A 1 223 ? 196.489 177.559 185.543 1.00 38.86 ?  223 LEU   A CA  1 
ATOM   1586 C C   . LEU   A 1 223 ? 196.802 176.979 184.171 1.00 38.86 ?  223 LEU   A C   1 
ATOM   1587 O O   . LEU   A 1 223 ? 197.920 176.500 183.960 1.00 38.86 ?  223 LEU   A O   1 
ATOM   1588 C CB  . LEU   A 1 223 ? 195.965 176.446 186.453 1.00 38.86 ?  223 LEU   A CB  1 
ATOM   1589 C CG  . LEU   A 1 223 ? 196.151 176.685 187.953 1.00 38.86 ?  223 LEU   A CG  1 
ATOM   1590 C CD1 . LEU   A 1 223 ? 195.370 175.659 188.756 1.00 38.86 ?  223 LEU   A CD1 1 
ATOM   1591 C CD2 . LEU   A 1 223 ? 197.624 176.654 188.331 1.00 38.86 ?  223 LEU   A CD2 1 
ATOM   1592 N N   . THR   A 1 224 ? 195.846 177.001 183.245 1.00 40.43 ?  224 THR   A N   1 
ATOM   1593 C CA  . THR   A 1 224 ? 196.111 176.680 181.849 1.00 40.43 ?  224 THR   A CA  1 
ATOM   1594 C C   . THR   A 1 224 ? 197.004 177.708 181.177 1.00 40.43 ?  224 THR   A C   1 
ATOM   1595 O O   . THR   A 1 224 ? 197.880 177.338 180.391 1.00 40.43 ?  224 THR   A O   1 
ATOM   1596 C CB  . THR   A 1 224 ? 194.800 176.583 181.063 1.00 40.43 ?  224 THR   A CB  1 
ATOM   1597 O OG1 . THR   A 1 224 ? 193.980 177.718 181.363 1.00 40.43 ?  224 THR   A OG1 1 
ATOM   1598 C CG2 . THR   A 1 224 ? 194.048 175.314 181.425 1.00 40.43 ?  224 THR   A CG2 1 
ATOM   1599 N N   . VAL   A 1 225 ? 196.798 178.991 181.472 1.00 40.61 ?  225 VAL   A N   1 
ATOM   1600 C CA  . VAL   A 1 225 ? 197.717 180.015 180.988 1.00 40.61 ?  225 VAL   A CA  1 
ATOM   1601 C C   . VAL   A 1 225 ? 199.121 179.753 181.517 1.00 40.61 ?  225 VAL   A C   1 
ATOM   1602 O O   . VAL   A 1 225 ? 200.110 179.887 180.789 1.00 40.61 ?  225 VAL   A O   1 
ATOM   1603 C CB  . VAL   A 1 225 ? 197.214 181.414 181.388 1.00 40.61 ?  225 VAL   A CB  1 
ATOM   1604 C CG1 . VAL   A 1 225 ? 198.294 182.459 181.150 1.00 40.61 ?  225 VAL   A CG1 1 
ATOM   1605 C CG2 . VAL   A 1 225 ? 195.951 181.766 180.617 1.00 40.61 ?  225 VAL   A CG2 1 
ATOM   1606 N N   . VAL   A 1 226 ? 199.231 179.382 182.792 1.00 40.07 ?  226 VAL   A N   1 
ATOM   1607 C CA  . VAL   A 1 226 ? 200.540 179.099 183.373 1.00 40.07 ?  226 VAL   A CA  1 
ATOM   1608 C C   . VAL   A 1 226 ? 201.176 177.892 182.697 1.00 40.07 ?  226 VAL   A C   1 
ATOM   1609 O O   . VAL   A 1 226 ? 202.382 177.879 182.432 1.00 40.07 ?  226 VAL   A O   1 
ATOM   1610 C CB  . VAL   A 1 226 ? 200.420 178.894 184.893 1.00 40.07 ?  226 VAL   A CB  1 
ATOM   1611 C CG1 . VAL   A 1 226 ? 201.699 178.286 185.449 1.00 40.07 ?  226 VAL   A CG1 1 
ATOM   1612 C CG2 . VAL   A 1 226 ? 200.113 180.215 185.584 1.00 40.07 ?  226 VAL   A CG2 1 
ATOM   1613 N N   . VAL   A 1 227 ? 200.384 176.855 182.418 1.00 40.74 ?  227 VAL   A N   1 
ATOM   1614 C CA  . VAL   A 1 227 ? 200.919 175.678 181.735 1.00 40.74 ?  227 VAL   A CA  1 
ATOM   1615 C C   . VAL   A 1 227 ? 201.406 176.049 180.340 1.00 40.74 ?  227 VAL   A C   1 
ATOM   1616 O O   . VAL   A 1 227 ? 202.457 175.580 179.883 1.00 40.74 ?  227 VAL   A O   1 
ATOM   1617 C CB  . VAL   A 1 227 ? 199.858 174.562 181.684 1.00 40.74 ?  227 VAL   A CB  1 
ATOM   1618 C CG1 . VAL   A 1 227 ? 200.205 173.540 180.615 1.00 40.74 ?  227 VAL   A CG1 1 
ATOM   1619 C CG2 . VAL   A 1 227 ? 199.730 173.890 183.043 1.00 40.74 ?  227 VAL   A CG2 1 
ATOM   1620 N N   . GLY   A 1 228 ? 200.635 176.870 179.630 1.00 41.85 ?  228 GLY   A N   1 
ATOM   1621 C CA  . GLY   A 1 228 ? 201.068 177.327 178.323 1.00 41.85 ?  228 GLY   A CA  1 
ATOM   1622 C C   . GLY   A 1 228 ? 202.359 178.117 178.388 1.00 41.85 ?  228 GLY   A C   1 
ATOM   1623 O O   . GLY   A 1 228 ? 203.240 177.952 177.546 1.00 41.85 ?  228 GLY   A O   1 
ATOM   1624 N N   . ILE   A 1 229 ? 202.493 178.982 179.391 1.00 43.46 ?  229 ILE   A N   1 
ATOM   1625 C CA  . ILE   A 1 229 ? 203.734 179.733 179.549 1.00 43.46 ?  229 ILE   A CA  1 
ATOM   1626 C C   . ILE   A 1 229 ? 204.889 178.792 179.865 1.00 43.46 ?  229 ILE   A C   1 
ATOM   1627 O O   . ILE   A 1 229 ? 206.028 179.028 179.451 1.00 43.46 ?  229 ILE   A O   1 
ATOM   1628 C CB  . ILE   A 1 229 ? 203.577 180.811 180.636 1.00 43.46 ?  229 ILE   A CB  1 
ATOM   1629 C CG1 . ILE   A 1 229 ? 202.543 181.863 180.216 1.00 43.46 ?  229 ILE   A CG1 1 
ATOM   1630 C CG2 . ILE   A 1 229 ? 204.920 181.458 180.931 1.00 43.46 ?  229 ILE   A CG2 1 
ATOM   1631 C CD1 . ILE   A 1 229 ? 202.879 182.606 178.941 1.00 43.46 ?  229 ILE   A CD1 1 
ATOM   1632 N N   . ALA   A 1 230 ? 204.624 177.726 180.620 1.00 39.58 ?  230 ALA   A N   1 
ATOM   1633 C CA  . ALA   A 1 230 ? 205.698 176.815 180.999 1.00 39.58 ?  230 ALA   A CA  1 
ATOM   1634 C C   . ALA   A 1 230 ? 206.180 175.999 179.812 1.00 39.58 ?  230 ALA   A C   1 
ATOM   1635 O O   . ALA   A 1 230 ? 207.388 175.845 179.608 1.00 39.58 ?  230 ALA   A O   1 
ATOM   1636 C CB  . ALA   A 1 230 ? 205.232 175.890 182.120 1.00 39.58 ?  230 ALA   A CB  1 
ATOM   1637 N N   . VAL   A 1 231 ? 205.254 175.471 179.016 1.00 41.85 ?  231 VAL   A N   1 
ATOM   1638 C CA  . VAL   A 1 231 ? 205.612 174.525 177.964 1.00 41.85 ?  231 VAL   A CA  1 
ATOM   1639 C C   . VAL   A 1 231 ? 205.943 175.268 176.678 1.00 41.85 ?  231 VAL   A C   1 
ATOM   1640 O O   . VAL   A 1 231 ? 207.001 175.053 176.078 1.00 41.85 ?  231 VAL   A O   1 
ATOM   1641 C CB  . VAL   A 1 231 ? 204.486 173.504 177.723 1.00 41.85 ?  231 VAL   A CB  1 
ATOM   1642 C CG1 . VAL   A 1 231 ? 204.680 172.800 176.385 1.00 41.85 ?  231 VAL   A CG1 1 
ATOM   1643 C CG2 . VAL   A 1 231 ? 204.435 172.487 178.856 1.00 41.85 ?  231 VAL   A CG2 1 
ATOM   1644 N N   . VAL   A 1 232 ? 205.038 176.140 176.246 1.00 43.63 ?  232 VAL   A N   1 
ATOM   1645 C CA  . VAL   A 1 232 ? 205.174 176.849 174.981 1.00 43.63 ?  232 VAL   A CA  1 
ATOM   1646 C C   . VAL   A 1 232 ? 205.855 178.190 175.245 1.00 43.63 ?  232 VAL   A C   1 
ATOM   1647 O O   . VAL   A 1 232 ? 205.838 179.092 174.401 1.00 43.63 ?  232 VAL   A O   1 
ATOM   1648 C CB  . VAL   A 1 232 ? 203.794 177.031 174.320 1.00 43.63 ?  232 VAL   A CB  1 
ATOM   1649 C CG1 . VAL   A 1 232 ? 203.888 177.855 173.038 1.00 43.63 ?  232 VAL   A CG1 1 
ATOM   1650 C CG2 . VAL   A 1 232 ? 203.131 175.687 174.061 1.00 43.63 ?  232 VAL   A CG2 1 
ATOM   1651 N N   . GLY   A 1 233 ? 206.463 178.332 176.417 1.00 44.41 ?  233 GLY   A N   1 
ATOM   1652 C CA  . GLY   A 1 233 ? 207.094 179.582 176.774 1.00 44.41 ?  233 GLY   A CA  1 
ATOM   1653 C C   . GLY   A 1 233 ? 208.336 179.853 175.957 1.00 44.41 ?  233 GLY   A C   1 
ATOM   1654 O O   . GLY   A 1 233 ? 208.883 178.989 175.274 1.00 44.41 ?  233 GLY   A O   1 
ATOM   1655 N N   . GLU   A 1 234 ? 208.784 181.104 176.027 1.00 49.98 ?  234 GLU   A N   1 
ATOM   1656 C CA  . GLU   A 1 234 ? 209.937 181.625 175.305 1.00 49.98 ?  234 GLU   A CA  1 
ATOM   1657 C C   . GLU   A 1 234 ? 209.681 181.719 173.806 1.00 49.98 ?  234 GLU   A C   1 
ATOM   1658 O O   . GLU   A 1 234 ? 210.549 182.212 173.074 1.00 49.98 ?  234 GLU   A O   1 
ATOM   1659 C CB  . GLU   A 1 234 ? 211.202 180.786 175.541 1.00 49.98 ?  234 GLU   A CB  1 
ATOM   1660 C CG  . GLU   A 1 234 ? 211.499 180.490 177.008 1.00 49.98 ?  234 GLU   A CG  1 
ATOM   1661 C CD  . GLU   A 1 234 ? 212.152 181.658 177.727 1.00 49.98 ?  234 GLU   A CD  1 
ATOM   1662 O OE1 . GLU   A 1 234 ? 212.659 182.573 177.045 1.00 49.98 ?  234 GLU   A OE1 1 
ATOM   1663 O OE2 . GLU   A 1 234 ? 212.159 181.659 178.976 1.00 49.98 -1 234 GLU   A OE2 1 
ATOM   1664 N N   . GLN   A 1 235 ? 208.531 181.265 173.325 1.00 47.20 ?  235 GLN   A N   1 
ATOM   1665 C CA  . GLN   A 1 235 ? 208.145 181.382 171.924 1.00 47.20 ?  235 GLN   A CA  1 
ATOM   1666 C C   . GLN   A 1 235 ? 206.763 181.991 171.758 1.00 47.20 ?  235 GLN   A C   1 
ATOM   1667 O O   . GLN   A 1 235 ? 206.543 182.748 170.810 1.00 47.20 ?  235 GLN   A O   1 
ATOM   1668 C CB  . GLN   A 1 235 ? 208.197 180.006 171.241 1.00 47.20 ?  235 GLN   A CB  1 
ATOM   1669 C CG  . GLN   A 1 235 ? 207.570 178.873 172.034 1.00 47.20 ?  235 GLN   A CG  1 
ATOM   1670 C CD  . GLN   A 1 235 ? 207.852 177.515 171.421 1.00 47.20 ?  235 GLN   A CD  1 
ATOM   1671 O OE1 . GLN   A 1 235 ? 208.353 177.420 170.302 1.00 47.20 ?  235 GLN   A OE1 1 
ATOM   1672 N NE2 . GLN   A 1 235 ? 207.535 176.457 172.155 1.00 47.20 ?  235 GLN   A NE2 1 
ATOM   1673 N N   . GLY   A 1 236 ? 205.831 181.681 172.655 1.00 46.35 ?  236 GLY   A N   1 
ATOM   1674 C CA  . GLY   A 1 236 ? 204.550 182.356 172.678 1.00 46.35 ?  236 GLY   A CA  1 
ATOM   1675 C C   . GLY   A 1 236 ? 204.328 183.061 174.000 1.00 46.35 ?  236 GLY   A C   1 
ATOM   1676 O O   . GLY   A 1 236 ? 204.079 182.420 175.025 1.00 46.35 ?  236 GLY   A O   1 
ATOM   1677 N N   . ARG   A 1 237 ? 204.401 184.388 173.982 1.00 47.49 ?  237 ARG   A N   1 
ATOM   1678 C CA  . ARG   A 1 237 ? 204.309 185.191 175.189 1.00 47.49 ?  237 ARG   A CA  1 
ATOM   1679 C C   . ARG   A 1 237 ? 203.621 186.503 174.845 1.00 47.49 ?  237 ARG   A C   1 
ATOM   1680 O O   . ARG   A 1 237 ? 203.344 186.796 173.678 1.00 47.49 ?  237 ARG   A O   1 
ATOM   1681 C CB  . ARG   A 1 237 ? 205.692 185.453 175.798 1.00 47.49 ?  237 ARG   A CB  1 
ATOM   1682 C CG  . ARG   A 1 237 ? 206.488 184.210 176.153 1.00 47.49 ?  237 ARG   A CG  1 
ATOM   1683 C CD  . ARG   A 1 237 ? 205.825 183.404 177.259 1.00 47.49 ?  237 ARG   A CD  1 
ATOM   1684 N NE  . ARG   A 1 237 ? 206.104 183.932 178.589 1.00 47.49 ?  237 ARG   A NE  1 
ATOM   1685 C CZ  . ARG   A 1 237 ? 207.297 183.935 179.168 1.00 47.49 ?  237 ARG   A CZ  1 
ATOM   1686 N NH1 . ARG   A 1 237 ? 208.368 183.466 178.550 1.00 47.49 1  237 ARG   A NH1 1 
ATOM   1687 N NH2 . ARG   A 1 237 ? 207.419 184.421 180.400 1.00 47.49 ?  237 ARG   A NH2 1 
ATOM   1688 N N   . TYR   A 1 238 ? 203.354 187.304 175.876 1.00 51.01 ?  238 TYR   A N   1 
ATOM   1689 C CA  . TYR   A 1 238 ? 202.679 188.586 175.702 1.00 51.01 ?  238 TYR   A CA  1 
ATOM   1690 C C   . TYR   A 1 238 ? 201.383 188.386 174.925 1.00 51.01 ?  238 TYR   A C   1 
ATOM   1691 O O   . TYR   A 1 238 ? 201.010 189.185 174.063 1.00 51.01 ?  238 TYR   A O   1 
ATOM   1692 C CB  . TYR   A 1 238 ? 203.594 189.593 175.003 1.00 51.01 ?  238 TYR   A CB  1 
ATOM   1693 C CG  . TYR   A 1 238 ? 204.401 190.455 175.948 1.00 51.01 ?  238 TYR   A CG  1 
ATOM   1694 C CD1 . TYR   A 1 238 ? 205.780 190.538 175.828 1.00 51.01 ?  238 TYR   A CD1 1 
ATOM   1695 C CD2 . TYR   A 1 238 ? 203.788 191.183 176.956 1.00 51.01 ?  238 TYR   A CD2 1 
ATOM   1696 C CE1 . TYR   A 1 238 ? 206.526 191.321 176.686 1.00 51.01 ?  238 TYR   A CE1 1 
ATOM   1697 C CE2 . TYR   A 1 238 ? 204.524 191.969 177.820 1.00 51.01 ?  238 TYR   A CE2 1 
ATOM   1698 C CZ  . TYR   A 1 238 ? 205.893 192.035 177.681 1.00 51.01 ?  238 TYR   A CZ  1 
ATOM   1699 O OH  . TYR   A 1 238 ? 206.631 192.818 178.540 1.00 51.01 ?  238 TYR   A OH  1 
ATOM   1700 N N   . TYR   A 1 239 ? 200.691 187.292 175.237 1.00 48.58 ?  239 TYR   A N   1 
ATOM   1701 C CA  . TYR   A 1 239 ? 199.512 186.907 174.477 1.00 48.58 ?  239 TYR   A CA  1 
ATOM   1702 C C   . TYR   A 1 239 ? 198.352 187.865 174.712 1.00 48.58 ?  239 TYR   A C   1 
ATOM   1703 O O   . TYR   A 1 239 ? 197.404 187.876 173.920 1.00 48.58 ?  239 TYR   A O   1 
ATOM   1704 C CB  . TYR   A 1 239 ? 199.126 185.474 174.846 1.00 48.58 ?  239 TYR   A CB  1 
ATOM   1705 C CG  . TYR   A 1 239 ? 197.943 184.915 174.093 1.00 48.58 ?  239 TYR   A CG  1 
ATOM   1706 C CD1 . TYR   A 1 239 ? 198.071 184.499 172.773 1.00 48.58 ?  239 TYR   A CD1 1 
ATOM   1707 C CD2 . TYR   A 1 239 ? 196.703 184.793 174.701 1.00 48.58 ?  239 TYR   A CD2 1 
ATOM   1708 C CE1 . TYR   A 1 239 ? 196.997 183.980 172.081 1.00 48.58 ?  239 TYR   A CE1 1 
ATOM   1709 C CE2 . TYR   A 1 239 ? 195.621 184.277 174.015 1.00 48.58 ?  239 TYR   A CE2 1 
ATOM   1710 C CZ  . TYR   A 1 239 ? 195.774 183.873 172.706 1.00 48.58 ?  239 TYR   A CZ  1 
ATOM   1711 O OH  . TYR   A 1 239 ? 194.698 183.361 172.020 1.00 48.58 ?  239 TYR   A OH  1 
ATOM   1712 N N   . PHE   A 1 240 ? 198.412 188.673 175.778 1.00 53.76 ?  240 PHE   A N   1 
ATOM   1713 C CA  . PHE   A 1 240 ? 197.386 189.663 176.077 1.00 53.76 ?  240 PHE   A CA  1 
ATOM   1714 C C   . PHE   A 1 240 ? 197.866 191.103 175.957 1.00 53.76 ?  240 PHE   A C   1 
ATOM   1715 O O   . PHE   A 1 240 ? 197.029 191.995 175.778 1.00 53.76 ?  240 PHE   A O   1 
ATOM   1716 C CB  . PHE   A 1 240 ? 196.825 189.451 177.494 1.00 53.76 ?  240 PHE   A CB  1 
ATOM   1717 C CG  . PHE   A 1 240 ? 197.856 189.564 178.587 1.00 53.76 ?  240 PHE   A CG  1 
ATOM   1718 C CD1 . PHE   A 1 240 ? 198.651 188.481 178.925 1.00 53.76 ?  240 PHE   A CD1 1 
ATOM   1719 C CD2 . PHE   A 1 240 ? 198.013 190.746 179.291 1.00 53.76 ?  240 PHE   A CD2 1 
ATOM   1720 C CE1 . PHE   A 1 240 ? 199.594 188.581 179.931 1.00 53.76 ?  240 PHE   A CE1 1 
ATOM   1721 C CE2 . PHE   A 1 240 ? 198.956 190.851 180.299 1.00 53.76 ?  240 PHE   A CE2 1 
ATOM   1722 C CZ  . PHE   A 1 240 ? 199.746 189.767 180.619 1.00 53.76 ?  240 PHE   A CZ  1 
ATOM   1723 N N   . THR   A 1 241 ? 199.169 191.359 176.049 1.00 54.26 ?  241 THR   A N   1 
ATOM   1724 C CA  . THR   A 1 241 ? 199.732 192.685 175.830 1.00 54.26 ?  241 THR   A CA  1 
ATOM   1725 C C   . THR   A 1 241 ? 200.511 192.681 174.522 1.00 54.26 ?  241 THR   A C   1 
ATOM   1726 O O   . THR   A 1 241 ? 201.209 191.710 174.214 1.00 54.26 ?  241 THR   A O   1 
ATOM   1727 C CB  . THR   A 1 241 ? 200.646 193.104 176.985 1.00 54.26 ?  241 THR   A CB  1 
ATOM   1728 O OG1 . THR   A 1 241 ? 199.884 193.214 178.192 1.00 54.26 ?  241 THR   A OG1 1 
ATOM   1729 C CG2 . THR   A 1 241 ? 201.309 194.443 176.690 1.00 54.26 ?  241 THR   A CG2 1 
ATOM   1730 N N   . ASP   A 1 242 ? 200.380 193.761 173.753 1.00 54.70 ?  242 ASP   A N   1 
ATOM   1731 C CA  . ASP   A 1 242 ? 200.973 193.936 172.431 1.00 54.70 ?  242 ASP   A CA  1 
ATOM   1732 C C   . ASP   A 1 242 ? 200.314 193.056 171.377 1.00 54.70 ?  242 ASP   A C   1 
ATOM   1733 O O   . ASP   A 1 242 ? 200.676 193.152 170.198 1.00 54.70 ?  242 ASP   A O   1 
ATOM   1734 C CB  . ASP   A 1 242 ? 202.484 193.659 172.424 1.00 54.70 ?  242 ASP   A CB  1 
ATOM   1735 C CG  . ASP   A 1 242 ? 203.253 194.603 173.325 1.00 54.70 ?  242 ASP   A CG  1 
ATOM   1736 O OD1 . ASP   A 1 242 ? 202.771 195.732 173.554 1.00 54.70 ?  242 ASP   A OD1 1 
ATOM   1737 O OD2 . ASP   A 1 242 ? 204.340 194.217 173.803 1.00 54.70 -1 242 ASP   A OD2 1 
ATOM   1738 N N   . LEU   A 1 243 ? 199.367 192.203 171.754 1.00 52.40 ?  243 LEU   A N   1 
ATOM   1739 C CA  . LEU   A 1 243 ? 198.612 191.384 170.814 1.00 52.40 ?  243 LEU   A CA  1 
ATOM   1740 C C   . LEU   A 1 243 ? 197.110 191.571 170.946 1.00 52.40 ?  243 LEU   A C   1 
ATOM   1741 O O   . LEU   A 1 243 ? 196.412 191.642 169.932 1.00 52.40 ?  243 LEU   A O   1 
ATOM   1742 C CB  . LEU   A 1 243 ? 198.964 189.901 171.014 1.00 52.40 ?  243 LEU   A CB  1 
ATOM   1743 C CG  . LEU   A 1 243 ? 198.513 188.918 169.931 1.00 52.40 ?  243 LEU   A CG  1 
ATOM   1744 C CD1 . LEU   A 1 243 ? 198.925 189.389 168.544 1.00 52.40 ?  243 LEU   A CD1 1 
ATOM   1745 C CD2 . LEU   A 1 243 ? 199.072 187.534 170.213 1.00 52.40 ?  243 LEU   A CD2 1 
ATOM   1746 N N   . LEU   A 1 244 ? 196.595 191.652 172.171 1.00 52.83 ?  244 LEU   A N   1 
ATOM   1747 C CA  . LEU   A 1 244 ? 195.187 191.909 172.460 1.00 52.83 ?  244 LEU   A CA  1 
ATOM   1748 C C   . LEU   A 1 244 ? 194.247 190.963 171.724 1.00 52.83 ?  244 LEU   A C   1 
ATOM   1749 O O   . LEU   A 1 244 ? 193.062 191.281 171.563 1.00 52.83 ?  244 LEU   A O   1 
ATOM   1750 C CB  . LEU   A 1 244 ? 194.810 193.360 172.133 1.00 52.83 ?  244 LEU   A CB  1 
ATOM   1751 C CG  . LEU   A 1 244 ? 195.465 194.446 172.987 1.00 52.83 ?  244 LEU   A CG  1 
ATOM   1752 C CD1 . LEU   A 1 244 ? 195.114 195.822 172.451 1.00 52.83 ?  244 LEU   A CD1 1 
ATOM   1753 C CD2 . LEU   A 1 244 ? 195.042 194.323 174.442 1.00 52.83 ?  244 LEU   A CD2 1 
ATOM   1754 N N   . GLY   A 1 245 ? 194.731 189.808 171.275 1.00 52.73 ?  245 GLY   A N   1 
ATOM   1755 C CA  . GLY   A 1 245 ? 193.892 188.920 170.497 1.00 52.73 ?  245 GLY   A CA  1 
ATOM   1756 C C   . GLY   A 1 245 ? 193.363 189.632 169.271 1.00 52.73 ?  245 GLY   A C   1 
ATOM   1757 O O   . GLY   A 1 245 ? 192.165 189.581 168.978 1.00 52.73 ?  245 GLY   A O   1 
ATOM   1758 N N   . LYS   A 1 246 ? 194.253 190.311 168.557 1.00 51.49 ?  246 LYS   A N   1 
ATOM   1759 C CA  . LYS   A 1 246 ? 193.833 191.194 167.480 1.00 51.49 ?  246 LYS   A CA  1 
ATOM   1760 C C   . LYS   A 1 246 ? 193.015 190.413 166.453 1.00 51.49 ?  246 LYS   A C   1 
ATOM   1761 O O   . LYS   A 1 246 ? 193.475 189.372 165.965 1.00 51.49 ?  246 LYS   A O   1 
ATOM   1762 C CB  . LYS   A 1 246 ? 195.051 191.827 166.810 1.00 51.49 ?  246 LYS   A CB  1 
ATOM   1763 C CG  . LYS   A 1 246 ? 194.760 193.153 166.109 1.00 51.49 ?  246 LYS   A CG  1 
ATOM   1764 C CD  . LYS   A 1 246 ? 194.747 194.381 167.036 1.00 51.49 ?  246 LYS   A CD  1 
ATOM   1765 C CE  . LYS   A 1 246 ? 195.984 194.519 167.927 1.00 51.49 ?  246 LYS   A CE  1 
ATOM   1766 N NZ  . LYS   A 1 246 ? 195.773 195.533 168.996 1.00 51.49 1  246 LYS   A NZ  1 
ATOM   1767 N N   . PRO   A 1 247 ? 191.810 190.871 166.101 1.00 47.55 ?  247 PRO   A N   1 
ATOM   1768 C CA  . PRO   A 1 247 ? 191.002 190.108 165.134 1.00 47.55 ?  247 PRO   A CA  1 
ATOM   1769 C C   . PRO   A 1 247 ? 191.660 189.967 163.773 1.00 47.55 ?  247 PRO   A C   1 
ATOM   1770 O O   . PRO   A 1 247 ? 191.467 188.944 163.105 1.00 47.55 ?  247 PRO   A O   1 
ATOM   1771 C CB  . PRO   A 1 247 ? 189.693 190.907 165.040 1.00 47.55 ?  247 PRO   A CB  1 
ATOM   1772 C CG  . PRO   A 1 247 ? 189.786 192.021 166.018 1.00 47.55 ?  247 PRO   A CG  1 
ATOM   1773 C CD  . PRO   A 1 247 ? 191.190 192.154 166.475 1.00 47.55 ?  247 PRO   A CD  1 
ATOM   1774 N N   . ASP   A 1 248 ? 192.430 190.967 163.339 1.00 49.77 ?  248 ASP   A N   1 
ATOM   1775 C CA  . ASP   A 1 248 ? 192.985 190.940 161.989 1.00 49.77 ?  248 ASP   A CA  1 
ATOM   1776 C C   . ASP   A 1 248 ? 193.905 189.742 161.787 1.00 49.77 ?  248 ASP   A C   1 
ATOM   1777 O O   . ASP   A 1 248 ? 193.855 189.084 160.741 1.00 49.77 ?  248 ASP   A O   1 
ATOM   1778 C CB  . ASP   A 1 248 ? 193.735 192.242 161.702 1.00 49.77 ?  248 ASP   A CB  1 
ATOM   1779 C CG  . ASP   A 1 248 ? 194.666 192.641 162.830 1.00 49.77 ?  248 ASP   A CG  1 
ATOM   1780 O OD1 . ASP   A 1 248 ? 195.182 191.741 163.523 1.00 49.77 ?  248 ASP   A OD1 1 
ATOM   1781 O OD2 . ASP   A 1 248 ? 194.879 193.856 163.023 1.00 49.77 -1 248 ASP   A OD2 1 
ATOM   1782 N N   . ARG   A 1 249 ? 194.753 189.444 162.774 1.00 51.13 ?  249 ARG   A N   1 
ATOM   1783 C CA  . ARG   A 1 249 ? 195.687 188.331 162.631 1.00 51.13 ?  249 ARG   A CA  1 
ATOM   1784 C C   . ARG   A 1 249 ? 194.953 187.003 162.500 1.00 51.13 ?  249 ARG   A C   1 
ATOM   1785 O O   . ARG   A 1 249 ? 195.367 186.133 161.726 1.00 51.13 ?  249 ARG   A O   1 
ATOM   1786 C CB  . ARG   A 1 249 ? 196.651 188.300 163.816 1.00 51.13 ?  249 ARG   A CB  1 
ATOM   1787 C CG  . ARG   A 1 249 ? 197.227 189.661 164.172 1.00 51.13 ?  249 ARG   A CG  1 
ATOM   1788 C CD  . ARG   A 1 249 ? 198.633 189.553 164.734 1.00 51.13 ?  249 ARG   A CD  1 
ATOM   1789 N NE  . ARG   A 1 249 ? 199.224 190.866 164.966 1.00 51.13 ?  249 ARG   A NE  1 
ATOM   1790 C CZ  . ARG   A 1 249 ? 200.415 191.068 165.513 1.00 51.13 ?  249 ARG   A CZ  1 
ATOM   1791 N NH1 . ARG   A 1 249 ? 201.179 190.060 165.902 1.00 51.13 1  249 ARG   A NH1 1 
ATOM   1792 N NH2 . ARG   A 1 249 ? 200.851 192.314 165.674 1.00 51.13 ?  249 ARG   A NH2 1 
ATOM   1793 N N   . ILE   A 1 250 ? 193.864 186.824 163.251 1.00 47.76 ?  250 ILE   A N   1 
ATOM   1794 C CA  . ILE   A 1 250 ? 193.107 185.578 163.172 1.00 47.76 ?  250 ILE   A CA  1 
ATOM   1795 C C   . ILE   A 1 250 ? 192.559 185.383 161.764 1.00 47.76 ?  250 ILE   A C   1 
ATOM   1796 O O   . ILE   A 1 250 ? 192.643 184.291 161.191 1.00 47.76 ?  250 ILE   A O   1 
ATOM   1797 C CB  . ILE   A 1 250 ? 191.983 185.564 164.223 1.00 47.76 ?  250 ILE   A CB  1 
ATOM   1798 C CG1 . ILE   A 1 250 ? 192.580 185.716 165.626 1.00 47.76 ?  250 ILE   A CG1 1 
ATOM   1799 C CG2 . ILE   A 1 250 ? 191.163 184.278 164.112 1.00 47.76 ?  250 ILE   A CG2 1 
ATOM   1800 C CD1 . ILE   A 1 250 ? 191.585 185.538 166.755 1.00 47.76 ?  250 ILE   A CD1 1 
ATOM   1801 N N   . GLY   A 1 251 ? 191.988 186.437 161.188 1.00 47.86 ?  251 GLY   A N   1 
ATOM   1802 C CA  . GLY   A 1 251 ? 191.441 186.363 159.855 1.00 47.86 ?  251 GLY   A CA  1 
ATOM   1803 C C   . GLY   A 1 251 ? 190.737 187.641 159.449 1.00 47.86 ?  251 GLY   A C   1 
ATOM   1804 O O   . GLY   A 1 251 ? 190.659 188.605 160.216 1.00 47.86 ?  251 GLY   A O   1 
ATOM   1805 N N   . PRO   A 1 252 ? 190.211 187.673 158.226 1.00 45.10 ?  252 PRO   A N   1 
ATOM   1806 C CA  . PRO   A 1 252 ? 189.493 188.868 157.770 1.00 45.10 ?  252 PRO   A CA  1 
ATOM   1807 C C   . PRO   A 1 252 ? 188.291 189.155 158.655 1.00 45.10 ?  252 PRO   A C   1 
ATOM   1808 O O   . PRO   A 1 252 ? 187.578 188.245 159.080 1.00 45.10 ?  252 PRO   A O   1 
ATOM   1809 C CB  . PRO   A 1 252 ? 189.074 188.510 156.340 1.00 45.10 ?  252 PRO   A CB  1 
ATOM   1810 C CG  . PRO   A 1 252 ? 189.097 187.024 156.291 1.00 45.10 ?  252 PRO   A CG  1 
ATOM   1811 C CD  . PRO   A 1 252 ? 190.184 186.595 157.224 1.00 45.10 ?  252 PRO   A CD  1 
ATOM   1812 N N   . ILE   A 1 253 ? 188.066 190.437 158.922 1.00 43.62 ?  253 ILE   A N   1 
ATOM   1813 C CA  . ILE   A 1 253 ? 186.979 190.844 159.804 1.00 43.62 ?  253 ILE   A CA  1 
ATOM   1814 C C   . ILE   A 1 253 ? 185.681 191.038 159.034 1.00 43.62 ?  253 ILE   A C   1 
ATOM   1815 O O   . ILE   A 1 253 ? 184.602 190.717 159.536 1.00 43.62 ?  253 ILE   A O   1 
ATOM   1816 C CB  . ILE   A 1 253 ? 187.372 192.125 160.565 1.00 43.62 ?  253 ILE   A CB  1 
ATOM   1817 C CG1 . ILE   A 1 253 ? 188.485 191.828 161.570 1.00 43.62 ?  253 ILE   A CG1 1 
ATOM   1818 C CG2 . ILE   A 1 253 ? 186.165 192.709 161.275 1.00 43.62 ?  253 ILE   A CG2 1 
ATOM   1819 C CD1 . ILE   A 1 253 ? 189.192 193.067 162.082 1.00 43.62 ?  253 ILE   A CD1 1 
ATOM   1820 N N   . ALA   A 1 254 ? 185.761 191.561 157.815 1.00 41.76 ?  254 ALA   A N   1 
ATOM   1821 C CA  . ALA   A 1 254 ? 184.583 191.943 157.050 1.00 41.76 ?  254 ALA   A CA  1 
ATOM   1822 C C   . ALA   A 1 254 ? 183.968 190.796 156.258 1.00 41.76 ?  254 ALA   A C   1 
ATOM   1823 O O   . ALA   A 1 254 ? 182.855 190.951 155.746 1.00 41.76 ?  254 ALA   A O   1 
ATOM   1824 C CB  . ALA   A 1 254 ? 184.935 193.081 156.093 1.00 41.76 ?  254 ALA   A CB  1 
ATOM   1825 N N   . THR   A 1 255 ? 184.650 189.660 156.136 1.00 41.00 ?  255 THR   A N   1 
ATOM   1826 C CA  . THR   A 1 255 ? 184.093 188.553 155.371 1.00 41.00 ?  255 THR   A CA  1 
ATOM   1827 C C   . THR   A 1 255 ? 182.761 188.125 155.970 1.00 41.00 ?  255 THR   A C   1 
ATOM   1828 O O   . THR   A 1 255 ? 182.593 188.086 157.191 1.00 41.00 ?  255 THR   A O   1 
ATOM   1829 C CB  . THR   A 1 255 ? 185.064 187.375 155.345 1.00 41.00 ?  255 THR   A CB  1 
ATOM   1830 O OG1 . THR   A 1 255 ? 184.548 186.350 154.489 1.00 41.00 ?  255 THR   A OG1 1 
ATOM   1831 C CG2 . THR   A 1 255 ? 185.266 186.812 156.735 1.00 41.00 ?  255 THR   A CG2 1 
ATOM   1832 N N   . VAL   A 1 256 ? 181.808 187.798 155.097 1.00 39.06 ?  256 VAL   A N   1 
ATOM   1833 C CA  . VAL   A 1 256 ? 180.435 187.579 155.545 1.00 39.06 ?  256 VAL   A CA  1 
ATOM   1834 C C   . VAL   A 1 256 ? 180.380 186.469 156.585 1.00 39.06 ?  256 VAL   A C   1 
ATOM   1835 O O   . VAL   A 1 256 ? 179.490 186.448 157.442 1.00 39.06 ?  256 VAL   A O   1 
ATOM   1836 C CB  . VAL   A 1 256 ? 179.524 187.276 154.342 1.00 39.06 ?  256 VAL   A CB  1 
ATOM   1837 C CG1 . VAL   A 1 256 ? 179.900 185.953 153.708 1.00 39.06 ?  256 VAL   A CG1 1 
ATOM   1838 C CG2 . VAL   A 1 256 ? 178.071 187.275 154.770 1.00 39.06 ?  256 VAL   A CG2 1 
ATOM   1839 N N   . PHE   A 1 257 ? 181.325 185.527 156.528 1.00 38.80 ?  257 PHE   A N   1 
ATOM   1840 C CA  . PHE   A 1 257 ? 181.339 184.444 157.505 1.00 38.80 ?  257 PHE   A CA  1 
ATOM   1841 C C   . PHE   A 1 257 ? 181.485 184.973 158.922 1.00 38.80 ?  257 PHE   A C   1 
ATOM   1842 O O   . PHE   A 1 257 ? 180.978 184.365 159.869 1.00 38.80 ?  257 PHE   A O   1 
ATOM   1843 C CB  . PHE   A 1 257 ? 182.471 183.469 157.194 1.00 38.80 ?  257 PHE   A CB  1 
ATOM   1844 C CG  . PHE   A 1 257 ? 182.304 182.752 155.892 1.00 38.80 ?  257 PHE   A CG  1 
ATOM   1845 C CD1 . PHE   A 1 257 ? 181.328 181.788 155.743 1.00 38.80 ?  257 PHE   A CD1 1 
ATOM   1846 C CD2 . PHE   A 1 257 ? 183.123 183.043 154.819 1.00 38.80 ?  257 PHE   A CD2 1 
ATOM   1847 C CE1 . PHE   A 1 257 ? 181.172 181.128 154.549 1.00 38.80 ?  257 PHE   A CE1 1 
ATOM   1848 C CE2 . PHE   A 1 257 ? 182.971 182.385 153.623 1.00 38.80 ?  257 PHE   A CE2 1 
ATOM   1849 C CZ  . PHE   A 1 257 ? 181.995 181.426 153.488 1.00 38.80 ?  257 PHE   A CZ  1 
ATOM   1850 N N   . ASN   A 1 258 ? 182.169 186.102 159.088 1.00 39.75 ?  258 ASN   A N   1 
ATOM   1851 C CA  . ASN   A 1 258 ? 182.314 186.713 160.401 1.00 39.75 ?  258 ASN   A CA  1 
ATOM   1852 C C   . ASN   A 1 258 ? 180.993 187.343 160.814 1.00 39.75 ?  258 ASN   A C   1 
ATOM   1853 O O   . ASN   A 1 258 ? 180.768 188.533 160.581 1.00 39.75 ?  258 ASN   A O   1 
ATOM   1854 C CB  . ASN   A 1 258 ? 183.426 187.760 160.382 1.00 39.75 ?  258 ASN   A CB  1 
ATOM   1855 C CG  . ASN   A 1 258 ? 183.705 188.331 161.747 1.00 39.75 ?  258 ASN   A CG  1 
ATOM   1856 O OD1 . ASN   A 1 258 ? 183.077 187.951 162.732 1.00 39.75 ?  258 ASN   A OD1 1 
ATOM   1857 N ND2 . ASN   A 1 258 ? 184.647 189.260 161.815 1.00 39.75 ?  258 ASN   A ND2 1 
ATOM   1858 N N   . GLN   A 1 259 ? 180.114 186.555 161.429 1.00 39.22 ?  259 GLN   A N   1 
ATOM   1859 C CA  . GLN   A 1 259 ? 178.750 187.008 161.666 1.00 39.22 ?  259 GLN   A CA  1 
ATOM   1860 C C   . GLN   A 1 259 ? 178.599 187.828 162.939 1.00 39.22 ?  259 GLN   A C   1 
ATOM   1861 O O   . GLN   A 1 259 ? 177.475 188.224 163.259 1.00 39.22 ?  259 GLN   A O   1 
ATOM   1862 C CB  . GLN   A 1 259 ? 177.807 185.805 161.705 1.00 39.22 ?  259 GLN   A CB  1 
ATOM   1863 C CG  . GLN   A 1 259 ? 177.381 185.322 160.329 1.00 39.22 ?  259 GLN   A CG  1 
ATOM   1864 C CD  . GLN   A 1 259 ? 176.673 186.398 159.532 1.00 39.22 ?  259 GLN   A CD  1 
ATOM   1865 O OE1 . GLN   A 1 259 ? 175.904 187.184 160.078 1.00 39.22 ?  259 GLN   A OE1 1 
ATOM   1866 N NE2 . GLN   A 1 259 ? 176.951 186.454 158.238 1.00 39.22 ?  259 GLN   A NE2 1 
ATOM   1867 N N   . SER   A 1 260 ? 179.676 188.097 163.669 1.00 40.16 ?  260 SER   A N   1 
ATOM   1868 C CA  . SER   A 1 260 ? 179.576 188.987 164.813 1.00 40.16 ?  260 SER   A CA  1 
ATOM   1869 C C   . SER   A 1 260 ? 179.169 190.385 164.358 1.00 40.16 ?  260 SER   A C   1 
ATOM   1870 O O   . SER   A 1 260 ? 179.140 190.697 163.166 1.00 40.16 ?  260 SER   A O   1 
ATOM   1871 C CB  . SER   A 1 260 ? 180.906 189.052 165.560 1.00 40.16 ?  260 SER   A CB  1 
ATOM   1872 O OG  . SER   A 1 260 ? 181.754 190.034 164.993 1.00 40.16 ?  260 SER   A OG  1 
ATOM   1873 N N   . TRP   A 1 261 ? 178.852 191.238 165.333 1.00 41.14 ?  261 TRP   A N   1 
ATOM   1874 C CA  . TRP   A 1 261 ? 178.524 192.625 165.020 1.00 41.14 ?  261 TRP   A CA  1 
ATOM   1875 C C   . TRP   A 1 261 ? 179.616 193.272 164.183 1.00 41.14 ?  261 TRP   A C   1 
ATOM   1876 O O   . TRP   A 1 261 ? 179.329 194.031 163.250 1.00 41.14 ?  261 TRP   A O   1 
ATOM   1877 C CB  . TRP   A 1 261 ? 178.321 193.422 166.307 1.00 41.14 ?  261 TRP   A CB  1 
ATOM   1878 C CG  . TRP   A 1 261 ? 176.940 193.366 166.867 1.00 41.14 ?  261 TRP   A CG  1 
ATOM   1879 C CD1 . TRP   A 1 261 ? 176.518 192.638 167.937 1.00 41.14 ?  261 TRP   A CD1 1 
ATOM   1880 C CD2 . TRP   A 1 261 ? 175.798 194.078 166.390 1.00 41.14 ?  261 TRP   A CD2 1 
ATOM   1881 N NE1 . TRP   A 1 261 ? 175.182 192.851 168.156 1.00 41.14 ?  261 TRP   A NE1 1 
ATOM   1882 C CE2 . TRP   A 1 261 ? 174.716 193.733 167.217 1.00 41.14 ?  261 TRP   A CE2 1 
ATOM   1883 C CE3 . TRP   A 1 261 ? 175.585 194.973 165.340 1.00 41.14 ?  261 TRP   A CE3 1 
ATOM   1884 C CZ2 . TRP   A 1 261 ? 173.440 194.250 167.028 1.00 41.14 ?  261 TRP   A CZ2 1 
ATOM   1885 C CZ3 . TRP   A 1 261 ? 174.320 195.487 165.155 1.00 41.14 ?  261 TRP   A CZ3 1 
ATOM   1886 C CH2 . TRP   A 1 261 ? 173.263 195.124 165.994 1.00 41.14 ?  261 TRP   A CH2 1 
ATOM   1887 N N   . ARG   A 1 262 ? 180.878 192.992 164.509 1.00 41.49 ?  262 ARG   A N   1 
ATOM   1888 C CA  . ARG   A 1 262 ? 181.982 193.632 163.805 1.00 41.49 ?  262 ARG   A CA  1 
ATOM   1889 C C   . ARG   A 1 262 ? 181.947 193.299 162.321 1.00 41.49 ?  262 ARG   A C   1 
ATOM   1890 O O   . ARG   A 1 262 ? 182.097 194.188 161.475 1.00 41.49 ?  262 ARG   A O   1 
ATOM   1891 C CB  . ARG   A 1 262 ? 183.311 193.200 164.425 1.00 41.49 ?  262 ARG   A CB  1 
ATOM   1892 C CG  . ARG   A 1 262 ? 183.710 194.017 165.643 1.00 41.49 ?  262 ARG   A CG  1 
ATOM   1893 C CD  . ARG   A 1 262 ? 182.776 193.732 166.809 1.00 41.49 ?  262 ARG   A CD  1 
ATOM   1894 N NE  . ARG   A 1 262 ? 183.198 194.378 168.045 1.00 41.49 ?  262 ARG   A NE  1 
ATOM   1895 C CZ  . ARG   A 1 262 ? 182.488 194.377 169.164 1.00 41.49 ?  262 ARG   A CZ  1 
ATOM   1896 N NH1 . ARG   A 1 262 ? 181.304 193.788 169.232 1.00 41.49 1  262 ARG   A NH1 1 
ATOM   1897 N NH2 . ARG   A 1 262 ? 182.971 194.993 170.240 1.00 41.49 ?  262 ARG   A NH2 1 
ATOM   1898 N N   . GLY   A 1 263 ? 181.718 192.030 161.985 1.00 40.39 ?  263 GLY   A N   1 
ATOM   1899 C CA  . GLY   A 1 263 ? 181.701 191.646 160.585 1.00 40.39 ?  263 GLY   A CA  1 
ATOM   1900 C C   . GLY   A 1 263 ? 180.619 192.359 159.797 1.00 40.39 ?  263 GLY   A C   1 
ATOM   1901 O O   . GLY   A 1 263 ? 180.895 192.990 158.777 1.00 40.39 ?  263 GLY   A O   1 
ATOM   1902 N N   . GLY   A 1 264 ? 179.375 192.282 160.271 1.00 39.51 ?  264 GLY   A N   1 
ATOM   1903 C CA  . GLY   A 1 264 ? 178.278 192.902 159.543 1.00 39.51 ?  264 GLY   A CA  1 
ATOM   1904 C C   . GLY   A 1 264 ? 178.401 194.411 159.461 1.00 39.51 ?  264 GLY   A C   1 
ATOM   1905 O O   . GLY   A 1 264 ? 178.090 195.015 158.430 1.00 39.51 ?  264 GLY   A O   1 
ATOM   1906 N N   . ILE   A 1 265 ? 178.842 195.042 160.548 1.00 41.46 ?  265 ILE   A N   1 
ATOM   1907 C CA  . ILE   A 1 265 ? 179.016 196.490 160.538 1.00 41.46 ?  265 ILE   A CA  1 
ATOM   1908 C C   . ILE   A 1 265 ? 180.102 196.883 159.546 1.00 41.46 ?  265 ILE   A C   1 
ATOM   1909 O O   . ILE   A 1 265 ? 179.995 197.900 158.853 1.00 41.46 ?  265 ILE   A O   1 
ATOM   1910 C CB  . ILE   A 1 265 ? 179.329 196.999 161.953 1.00 41.46 ?  265 ILE   A CB  1 
ATOM   1911 C CG1 . ILE   A 1 265 ? 178.154 196.719 162.893 1.00 41.46 ?  265 ILE   A CG1 1 
ATOM   1912 C CG2 . ILE   A 1 265 ? 179.630 198.481 161.916 1.00 41.46 ?  265 ILE   A CG2 1 
ATOM   1913 C CD1 . ILE   A 1 265 ? 178.477 196.949 164.358 1.00 41.46 ?  265 ILE   A CD1 1 
ATOM   1914 N N   . SER   A 1 266 ? 181.171 196.086 159.467 1.00 41.76 ?  266 SER   A N   1 
ATOM   1915 C CA  . SER   A 1 266 ? 182.208 196.348 158.475 1.00 41.76 ?  266 SER   A CA  1 
ATOM   1916 C C   . SER   A 1 266 ? 181.675 196.169 157.058 1.00 41.76 ?  266 SER   A C   1 
ATOM   1917 O O   . SER   A 1 266 ? 182.020 196.939 156.154 1.00 41.76 ?  266 SER   A O   1 
ATOM   1918 C CB  . SER   A 1 266 ? 183.404 195.432 158.721 1.00 41.76 ?  266 SER   A CB  1 
ATOM   1919 O OG  . SER   A 1 266 ? 183.885 195.580 160.045 1.00 41.76 ?  266 SER   A OG  1 
ATOM   1920 N N   . ARG   A 1 267 ? 180.839 195.153 156.841 1.00 39.94 ?  267 ARG   A N   1 
ATOM   1921 C CA  . ARG   A 1 267 ? 180.223 194.985 155.528 1.00 39.94 ?  267 ARG   A CA  1 
ATOM   1922 C C   . ARG   A 1 267 ? 179.418 196.218 155.141 1.00 39.94 ?  267 ARG   A C   1 
ATOM   1923 O O   . ARG   A 1 267 ? 179.621 196.788 154.063 1.00 39.94 ?  267 ARG   A O   1 
ATOM   1924 C CB  . ARG   A 1 267 ? 179.324 193.749 155.516 1.00 39.94 ?  267 ARG   A CB  1 
ATOM   1925 C CG  . ARG   A 1 267 ? 180.020 192.461 155.896 1.00 39.94 ?  267 ARG   A CG  1 
ATOM   1926 C CD  . ARG   A 1 267 ? 179.156 191.247 155.627 1.00 39.94 ?  267 ARG   A CD  1 
ATOM   1927 N NE  . ARG   A 1 267 ? 178.492 190.793 156.845 1.00 39.94 ?  267 ARG   A NE  1 
ATOM   1928 C CZ  . ARG   A 1 267 ? 179.109 190.239 157.880 1.00 39.94 ?  267 ARG   A CZ  1 
ATOM   1929 N NH1 . ARG   A 1 267 ? 180.417 190.044 157.884 1.00 39.94 1  267 ARG   A NH1 1 
ATOM   1930 N NH2 . ARG   A 1 267 ? 178.395 189.884 158.945 1.00 39.94 ?  267 ARG   A NH2 1 
ATOM   1931 N N   . ILE   A 1 268 ? 178.517 196.660 156.016 1.00 40.27 ?  268 ILE   A N   1 
ATOM   1932 C CA  . ILE   A 1 268 ? 177.650 197.794 155.706 1.00 40.27 ?  268 ILE   A CA  1 
ATOM   1933 C C   . ILE   A 1 268 ? 178.462 199.082 155.674 1.00 40.27 ?  268 ILE   A C   1 
ATOM   1934 O O   . ILE   A 1 268 ? 177.984 200.111 155.186 1.00 40.27 ?  268 ILE   A O   1 
ATOM   1935 C CB  . ILE   A 1 268 ? 176.486 197.918 156.708 1.00 40.27 ?  268 ILE   A CB  1 
ATOM   1936 C CG1 . ILE   A 1 268 ? 175.452 198.920 156.194 1.00 40.27 ?  268 ILE   A CG1 1 
ATOM   1937 C CG2 . ILE   A 1 268 ? 176.987 198.362 158.068 1.00 40.27 ?  268 ILE   A CG2 1 
ATOM   1938 C CD1 . ILE   A 1 268 ? 174.131 198.847 156.914 1.00 40.27 ?  268 ILE   A CD1 1 
ATOM   1939 N N   . LEU   A 1 269 ? 179.689 199.042 156.197 1.00 43.09 ?  269 LEU   A N   1 
ATOM   1940 C CA  . LEU   A 1 269 ? 180.498 200.254 156.248 1.00 43.09 ?  269 LEU   A CA  1 
ATOM   1941 C C   . LEU   A 1 269 ? 181.493 200.344 155.099 1.00 43.09 ?  269 LEU   A C   1 
ATOM   1942 O O   . LEU   A 1 269 ? 181.662 201.422 154.519 1.00 43.09 ?  269 LEU   A O   1 
ATOM   1943 C CB  . LEU   A 1 269 ? 181.251 200.322 157.575 1.00 43.09 ?  269 LEU   A CB  1 
ATOM   1944 C CG  . LEU   A 1 269 ? 180.518 200.996 158.732 1.00 43.09 ?  269 LEU   A CG  1 
ATOM   1945 C CD1 . LEU   A 1 269 ? 181.381 200.971 159.977 1.00 43.09 ?  269 LEU   A CD1 1 
ATOM   1946 C CD2 . LEU   A 1 269 ? 180.137 202.426 158.380 1.00 43.09 ?  269 LEU   A CD2 1 
ATOM   1947 N N   . GLY   A 1 270 ? 182.149 199.240 154.753 1.00 44.77 ?  270 GLY   A N   1 
ATOM   1948 C CA  . GLY   A 1 270 ? 183.275 199.289 153.844 1.00 44.77 ?  270 GLY   A CA  1 
ATOM   1949 C C   . GLY   A 1 270 ? 184.610 199.530 154.512 1.00 44.77 ?  270 GLY   A C   1 
ATOM   1950 O O   . GLY   A 1 270 ? 185.633 199.575 153.820 1.00 44.77 ?  270 GLY   A O   1 
ATOM   1951 N N   . HIS   A 1 271 ? 184.633 199.686 155.833 1.00 44.28 ?  271 HIS   A N   1 
ATOM   1952 C CA  . HIS   A 1 271 ? 185.866 199.864 156.586 1.00 44.28 ?  271 HIS   A CA  1 
ATOM   1953 C C   . HIS   A 1 271 ? 185.623 199.411 158.016 1.00 44.28 ?  271 HIS   A C   1 
ATOM   1954 O O   . HIS   A 1 271 ? 184.605 199.756 158.621 1.00 44.28 ?  271 HIS   A O   1 
ATOM   1955 C CB  . HIS   A 1 271 ? 186.339 201.322 156.557 1.00 44.28 ?  271 HIS   A CB  1 
ATOM   1956 C CG  . HIS   A 1 271 ? 185.290 202.307 156.972 1.00 44.28 ?  271 HIS   A CG  1 
ATOM   1957 N ND1 . HIS   A 1 271 ? 184.645 202.243 158.188 1.00 44.28 ?  271 HIS   A ND1 1 
ATOM   1958 C CD2 . HIS   A 1 271 ? 184.772 203.380 156.328 1.00 44.28 ?  271 HIS   A CD2 1 
ATOM   1959 C CE1 . HIS   A 1 271 ? 183.776 203.235 158.277 1.00 44.28 ?  271 HIS   A CE1 1 
ATOM   1960 N NE2 . HIS   A 1 271 ? 183.834 203.939 157.161 1.00 44.28 ?  271 HIS   A NE2 1 
ATOM   1961 N N   . ASP   A 1 272 ? 186.575 198.653 158.552 1.00 44.37 ?  272 ASP   A N   1 
ATOM   1962 C CA  . ASP   A 1 272 ? 186.423 198.044 159.871 1.00 44.37 ?  272 ASP   A CA  1 
ATOM   1963 C C   . ASP   A 1 272 ? 186.367 199.149 160.913 1.00 44.37 ?  272 ASP   A C   1 
ATOM   1964 O O   . ASP   A 1 272 ? 187.382 199.766 161.240 1.00 44.37 ?  272 ASP   A O   1 
ATOM   1965 C CB  . ASP   A 1 272 ? 187.571 197.082 160.152 1.00 44.37 ?  272 ASP   A CB  1 
ATOM   1966 C CG  . ASP   A 1 272 ? 187.522 195.848 159.279 1.00 44.37 ?  272 ASP   A CG  1 
ATOM   1967 O OD1 . ASP   A 1 272 ? 186.409 195.444 158.884 1.00 44.37 ?  272 ASP   A OD1 1 
ATOM   1968 O OD2 . ASP   A 1 272 ? 188.595 195.281 158.983 1.00 44.37 -1 272 ASP   A OD2 1 
ATOM   1969 N N   . ALA   A 1 273 ? 185.167 199.404 161.439 1.00 45.17 ?  273 ALA   A N   1 
ATOM   1970 C CA  . ALA   A 1 273 ? 185.028 200.388 162.506 1.00 45.17 ?  273 ALA   A CA  1 
ATOM   1971 C C   . ALA   A 1 273 ? 185.697 199.916 163.789 1.00 45.17 ?  273 ALA   A C   1 
ATOM   1972 O O   . ALA   A 1 273 ? 186.265 200.728 164.529 1.00 45.17 ?  273 ALA   A O   1 
ATOM   1973 C CB  . ALA   A 1 273 ? 183.550 200.687 162.754 1.00 45.17 ?  273 ALA   A CB  1 
ATOM   1974 N N   . GLY   A 1 274 ? 185.644 198.618 164.071 1.00 45.52 ?  274 GLY   A N   1 
ATOM   1975 C CA  . GLY   A 1 274 ? 186.247 198.088 165.275 1.00 45.52 ?  274 GLY   A CA  1 
ATOM   1976 C C   . GLY   A 1 274 ? 185.629 198.675 166.525 1.00 45.52 ?  274 GLY   A C   1 
ATOM   1977 O O   . GLY   A 1 274 ? 184.453 198.439 166.813 1.00 45.52 ?  274 GLY   A O   1 
ATOM   1978 N N   . SER   A 1 275 ? 186.412 199.450 167.274 1.00 49.32 ?  275 SER   A N   1 
ATOM   1979 C CA  . SER   A 1 275 ? 185.953 200.072 168.507 1.00 49.32 ?  275 SER   A CA  1 
ATOM   1980 C C   . SER   A 1 275 ? 185.251 201.405 168.265 1.00 49.32 ?  275 SER   A C   1 
ATOM   1981 O O   . SER   A 1 275 ? 185.159 202.224 169.186 1.00 49.32 ?  275 SER   A O   1 
ATOM   1982 C CB  . SER   A 1 275 ? 187.130 200.269 169.465 1.00 49.32 ?  275 SER   A CB  1 
ATOM   1983 O OG  . SER   A 1 275 ? 187.684 199.023 169.853 1.00 49.32 ?  275 SER   A OG  1 
ATOM   1984 N N   . GLY   A 1 276 ? 184.754 201.637 167.053 1.00 47.62 ?  276 GLY   A N   1 
ATOM   1985 C CA  . GLY   A 1 276 ? 184.097 202.887 166.733 1.00 47.62 ?  276 GLY   A CA  1 
ATOM   1986 C C   . GLY   A 1 276 ? 182.866 203.137 167.577 1.00 47.62 ?  276 GLY   A C   1 
ATOM   1987 O O   . GLY   A 1 276 ? 182.378 202.235 168.263 1.00 47.62 ?  276 GLY   A O   1 
ATOM   1988 N N   . VAL   A 1 277 ? 182.359 204.370 167.538 1.00 47.51 ?  277 VAL   A N   1 
ATOM   1989 C CA  . VAL   A 1 277 ? 181.177 204.715 168.323 1.00 47.51 ?  277 VAL   A CA  1 
ATOM   1990 C C   . VAL   A 1 277 ? 179.978 203.895 167.867 1.00 47.51 ?  277 VAL   A C   1 
ATOM   1991 O O   . VAL   A 1 277 ? 179.205 203.384 168.688 1.00 47.51 ?  277 VAL   A O   1 
ATOM   1992 C CB  . VAL   A 1 277 ? 180.898 206.226 168.223 1.00 47.51 ?  277 VAL   A CB  1 
ATOM   1993 C CG1 . VAL   A 1 277 ? 179.577 206.572 168.893 1.00 47.51 ?  277 VAL   A CG1 1 
ATOM   1994 C CG2 . VAL   A 1 277 ? 182.041 207.021 168.837 1.00 47.51 ?  277 VAL   A CG2 1 
ATOM   1995 N N   . LEU   A 1 278 ? 179.798 203.764 166.552 1.00 44.93 ?  278 LEU   A N   1 
ATOM   1996 C CA  . LEU   A 1 278 ? 178.626 203.066 166.038 1.00 44.93 ?  278 LEU   A CA  1 
ATOM   1997 C C   . LEU   A 1 278 ? 178.644 201.589 166.409 1.00 44.93 ?  278 LEU   A C   1 
ATOM   1998 O O   . LEU   A 1 278 ? 177.590 201.015 166.703 1.00 44.93 ?  278 LEU   A O   1 
ATOM   1999 C CB  . LEU   A 1 278 ? 178.529 203.274 164.524 1.00 44.93 ?  278 LEU   A CB  1 
ATOM   2000 C CG  . LEU   A 1 278 ? 179.667 202.798 163.614 1.00 44.93 ?  278 LEU   A CG  1 
ATOM   2001 C CD1 . LEU   A 1 278 ? 179.529 201.335 163.241 1.00 44.93 ?  278 LEU   A CD1 1 
ATOM   2002 C CD2 . LEU   A 1 278 ? 179.741 203.659 162.359 1.00 44.93 ?  278 LEU   A CD2 1 
ATOM   2003 N N   . VAL   A 1 279 ? 179.819 200.956 166.408 1.00 44.70 ?  279 VAL   A N   1 
ATOM   2004 C CA  . VAL   A 1 279 ? 179.901 199.571 166.867 1.00 44.70 ?  279 VAL   A CA  1 
ATOM   2005 C C   . VAL   A 1 279 ? 179.654 199.482 168.368 1.00 44.70 ?  279 VAL   A C   1 
ATOM   2006 O O   . VAL   A 1 279 ? 179.059 198.509 168.845 1.00 44.70 ?  279 VAL   A O   1 
ATOM   2007 C CB  . VAL   A 1 279 ? 181.257 198.947 166.499 1.00 44.70 ?  279 VAL   A CB  1 
ATOM   2008 C CG1 . VAL   A 1 279 ? 181.356 197.541 167.065 1.00 44.70 ?  279 VAL   A CG1 1 
ATOM   2009 C CG2 . VAL   A 1 279 ? 181.446 198.921 164.995 1.00 44.70 ?  279 VAL   A CG2 1 
ATOM   2010 N N   . LEU   A 1 280 ? 180.122 200.467 169.137 1.00 46.99 ?  280 LEU   A N   1 
ATOM   2011 C CA  . LEU   A 1 280 ? 179.893 200.449 170.577 1.00 46.99 ?  280 LEU   A CA  1 
ATOM   2012 C C   . LEU   A 1 280 ? 178.408 200.547 170.900 1.00 46.99 ?  280 LEU   A C   1 
ATOM   2013 O O   . LEU   A 1 280 ? 177.922 199.880 171.822 1.00 46.99 ?  280 LEU   A O   1 
ATOM   2014 C CB  . LEU   A 1 280 ? 180.661 201.590 171.243 1.00 46.99 ?  280 LEU   A CB  1 
ATOM   2015 C CG  . LEU   A 1 280 ? 182.131 201.321 171.570 1.00 46.99 ?  280 LEU   A CG  1 
ATOM   2016 C CD1 . LEU   A 1 280 ? 182.794 202.585 172.092 1.00 46.99 ?  280 LEU   A CD1 1 
ATOM   2017 C CD2 . LEU   A 1 280 ? 182.270 200.192 172.581 1.00 46.99 ?  280 LEU   A CD2 1 
ATOM   2018 N N   . PHE   A 1 281 ? 177.671 201.384 170.168 1.00 46.46 ?  281 PHE   A N   1 
ATOM   2019 C CA  . PHE   A 1 281 ? 176.235 201.486 170.408 1.00 46.46 ?  281 PHE   A CA  1 
ATOM   2020 C C   . PHE   A 1 281 ? 175.543 200.158 170.134 1.00 46.46 ?  281 PHE   A C   1 
ATOM   2021 O O   . PHE   A 1 281 ? 174.651 199.744 170.886 1.00 46.46 ?  281 PHE   A O   1 
ATOM   2022 C CB  . PHE   A 1 281 ? 175.629 202.593 169.544 1.00 46.46 ?  281 PHE   A CB  1 
ATOM   2023 C CG  . PHE   A 1 281 ? 176.009 203.987 169.973 1.00 46.46 ?  281 PHE   A CG  1 
ATOM   2024 C CD1 . PHE   A 1 281 ? 176.981 204.202 170.938 1.00 46.46 ?  281 PHE   A CD1 1 
ATOM   2025 C CD2 . PHE   A 1 281 ? 175.387 205.086 169.404 1.00 46.46 ?  281 PHE   A CD2 1 
ATOM   2026 C CE1 . PHE   A 1 281 ? 177.322 205.482 171.325 1.00 46.46 ?  281 PHE   A CE1 1 
ATOM   2027 C CE2 . PHE   A 1 281 ? 175.726 206.368 169.788 1.00 46.46 ?  281 PHE   A CE2 1 
ATOM   2028 C CZ  . PHE   A 1 281 ? 176.694 206.566 170.749 1.00 46.46 ?  281 PHE   A CZ  1 
ATOM   2029 N N   . ALA   A 1 282 ? 175.940 199.476 169.060 1.00 43.91 ?  282 ALA   A N   1 
ATOM   2030 C CA  . ALA   A 1 282 ? 175.379 198.161 168.776 1.00 43.91 ?  282 ALA   A CA  1 
ATOM   2031 C C   . ALA   A 1 282 ? 175.735 197.165 169.870 1.00 43.91 ?  282 ALA   A C   1 
ATOM   2032 O O   . ALA   A 1 282 ? 174.903 196.342 170.269 1.00 43.91 ?  282 ALA   A O   1 
ATOM   2033 C CB  . ALA   A 1 282 ? 175.873 197.666 167.419 1.00 43.91 ?  282 ALA   A CB  1 
ATOM   2034 N N   . TYR   A 1 283 ? 176.971 197.213 170.361 1.00 45.75 ?  283 TYR   A N   1 
ATOM   2035 C CA  . TYR   A 1 283 ? 177.359 196.318 171.442 1.00 45.75 ?  283 TYR   A CA  1 
ATOM   2036 C C   . TYR   A 1 283 ? 176.494 196.554 172.673 1.00 45.75 ?  283 TYR   A C   1 
ATOM   2037 O O   . TYR   A 1 283 ? 176.035 195.603 173.312 1.00 45.75 ?  283 TYR   A O   1 
ATOM   2038 C CB  . TYR   A 1 283 ? 178.838 196.511 171.775 1.00 45.75 ?  283 TYR   A CB  1 
ATOM   2039 C CG  . TYR   A 1 283 ? 179.257 195.920 173.102 1.00 45.75 ?  283 TYR   A CG  1 
ATOM   2040 C CD1 . TYR   A 1 283 ? 179.428 194.551 173.250 1.00 45.75 ?  283 TYR   A CD1 1 
ATOM   2041 C CD2 . TYR   A 1 283 ? 179.488 196.731 174.205 1.00 45.75 ?  283 TYR   A CD2 1 
ATOM   2042 C CE1 . TYR   A 1 283 ? 179.814 194.005 174.459 1.00 45.75 ?  283 TYR   A CE1 1 
ATOM   2043 C CE2 . TYR   A 1 283 ? 179.873 196.194 175.419 1.00 45.75 ?  283 TYR   A CE2 1 
ATOM   2044 C CZ  . TYR   A 1 283 ? 180.035 194.830 175.539 1.00 45.75 ?  283 TYR   A CZ  1 
ATOM   2045 O OH  . TYR   A 1 283 ? 180.419 194.288 176.744 1.00 45.75 ?  283 TYR   A OH  1 
ATOM   2046 N N   . ALA   A 1 284 ? 176.244 197.821 173.008 1.00 45.67 ?  284 ALA   A N   1 
ATOM   2047 C CA  . ALA   A 1 284 ? 175.416 198.132 174.170 1.00 45.67 ?  284 ALA   A CA  1 
ATOM   2048 C C   . ALA   A 1 284 ? 173.975 197.670 173.971 1.00 45.67 ?  284 ALA   A C   1 
ATOM   2049 O O   . ALA   A 1 284 ? 173.353 197.126 174.896 1.00 45.67 ?  284 ALA   A O   1 
ATOM   2050 C CB  . ALA   A 1 284 ? 175.461 199.632 174.456 1.00 45.67 ?  284 ALA   A CB  1 
ATOM   2051 N N   . VAL   A 1 285 ? 173.417 197.888 172.778 1.00 44.74 ?  285 VAL   A N   1 
ATOM   2052 C CA  . VAL   A 1 285 ? 172.022 197.519 172.564 1.00 44.74 ?  285 VAL   A CA  1 
ATOM   2053 C C   . VAL   A 1 285 ? 171.866 196.003 172.584 1.00 44.74 ?  285 VAL   A C   1 
ATOM   2054 O O   . VAL   A 1 285 ? 170.893 195.476 173.135 1.00 44.74 ?  285 VAL   A O   1 
ATOM   2055 C CB  . VAL   A 1 285 ? 171.480 198.138 171.261 1.00 44.74 ?  285 VAL   A CB  1 
ATOM   2056 C CG1 . VAL   A 1 285 ? 171.985 197.394 170.041 1.00 44.74 ?  285 VAL   A CG1 1 
ATOM   2057 C CG2 . VAL   A 1 285 ? 169.958 198.161 171.283 1.00 44.74 ?  285 VAL   A CG2 1 
ATOM   2058 N N   . THR   A 1 286 ? 172.820 195.271 172.002 1.00 43.71 ?  286 THR   A N   1 
ATOM   2059 C CA  . THR   A 1 286 ? 172.745 193.817 172.092 1.00 43.71 ?  286 THR   A CA  1 
ATOM   2060 C C   . THR   A 1 286 ? 172.994 193.338 173.517 1.00 43.71 ?  286 THR   A C   1 
ATOM   2061 O O   . THR   A 1 286 ? 172.437 192.316 173.927 1.00 43.71 ?  286 THR   A O   1 
ATOM   2062 C CB  . THR   A 1 286 ? 173.727 193.157 171.123 1.00 43.71 ?  286 THR   A CB  1 
ATOM   2063 O OG1 . THR   A 1 286 ? 173.508 191.741 171.115 1.00 43.71 ?  286 THR   A OG1 1 
ATOM   2064 C CG2 . THR   A 1 286 ? 175.164 193.440 171.513 1.00 43.71 ?  286 THR   A CG2 1 
ATOM   2065 N N   . ALA   A 1 287 ? 173.801 194.066 174.293 1.00 44.01 ?  287 ALA   A N   1 
ATOM   2066 C CA  . ALA   A 1 287 ? 173.958 193.731 175.703 1.00 44.01 ?  287 ALA   A CA  1 
ATOM   2067 C C   . ALA   A 1 287 ? 172.629 193.820 176.435 1.00 44.01 ?  287 ALA   A C   1 
ATOM   2068 O O   . ALA   A 1 287 ? 172.243 192.889 177.152 1.00 44.01 ?  287 ALA   A O   1 
ATOM   2069 C CB  . ALA   A 1 287 ? 174.989 194.654 176.350 1.00 44.01 ?  287 ALA   A CB  1 
ATOM   2070 N N   . ILE   A 1 288 ? 171.910 194.929 176.262 1.00 44.21 ?  288 ILE   A N   1 
ATOM   2071 C CA  . ILE   A 1 288 ? 170.636 195.073 176.960 1.00 44.21 ?  288 ILE   A CA  1 
ATOM   2072 C C   . ILE   A 1 288 ? 169.635 194.037 176.459 1.00 44.21 ?  288 ILE   A C   1 
ATOM   2073 O O   . ILE   A 1 288 ? 168.885 193.446 177.248 1.00 44.21 ?  288 ILE   A O   1 
ATOM   2074 C CB  . ILE   A 1 288 ? 170.098 196.512 176.831 1.00 44.21 ?  288 ILE   A CB  1 
ATOM   2075 C CG1 . ILE   A 1 288 ? 168.906 196.717 177.768 1.00 44.21 ?  288 ILE   A CG1 1 
ATOM   2076 C CG2 . ILE   A 1 288 ? 169.720 196.839 175.405 1.00 44.21 ?  288 ILE   A CG2 1 
ATOM   2077 C CD1 . ILE   A 1 288 ? 168.514 198.168 177.953 1.00 44.21 ?  288 ILE   A CD1 1 
ATOM   2078 N N   . LEU   A 1 289 ? 169.619 193.780 175.149 1.00 43.68 ?  289 LEU   A N   1 
ATOM   2079 C CA  . LEU   A 1 289 ? 168.687 192.793 174.616 1.00 43.68 ?  289 LEU   A CA  1 
ATOM   2080 C C   . LEU   A 1 289 ? 168.969 191.407 175.179 1.00 43.68 ?  289 LEU   A C   1 
ATOM   2081 O O   . LEU   A 1 289 ? 168.041 190.690 175.570 1.00 43.68 ?  289 LEU   A O   1 
ATOM   2082 C CB  . LEU   A 1 289 ? 168.759 192.774 173.090 1.00 43.68 ?  289 LEU   A CB  1 
ATOM   2083 C CG  . LEU   A 1 289 ? 168.146 193.976 172.366 1.00 43.68 ?  289 LEU   A CG  1 
ATOM   2084 C CD1 . LEU   A 1 289 ? 168.374 193.858 170.872 1.00 43.68 ?  289 LEU   A CD1 1 
ATOM   2085 C CD2 . LEU   A 1 289 ? 166.661 194.109 172.669 1.00 43.68 ?  289 LEU   A CD2 1 
ATOM   2086 N N   . ALA   A 1 290 ? 170.241 191.011 175.237 1.00 44.08 ?  290 ALA   A N   1 
ATOM   2087 C CA  . ALA   A 1 290 ? 170.576 189.685 175.744 1.00 44.08 ?  290 ALA   A CA  1 
ATOM   2088 C C   . ALA   A 1 290 ? 170.308 189.579 177.239 1.00 44.08 ?  290 ALA   A C   1 
ATOM   2089 O O   . ALA   A 1 290 ? 169.878 188.526 177.722 1.00 44.08 ?  290 ALA   A O   1 
ATOM   2090 C CB  . ALA   A 1 290 ? 172.034 189.356 175.435 1.00 44.08 ?  290 ALA   A CB  1 
ATOM   2091 N N   . PHE   A 1 291 ? 170.560 190.651 177.995 1.00 45.77 ?  291 PHE   A N   1 
ATOM   2092 C CA  . PHE   A 1 291 ? 170.234 190.618 179.416 1.00 45.77 ?  291 PHE   A CA  1 
ATOM   2093 C C   . PHE   A 1 291 ? 168.739 190.445 179.630 1.00 45.77 ?  291 PHE   A C   1 
ATOM   2094 O O   . PHE   A 1 291 ? 168.316 189.664 180.489 1.00 45.77 ?  291 PHE   A O   1 
ATOM   2095 C CB  . PHE   A 1 291 ? 170.713 191.886 180.114 1.00 45.77 ?  291 PHE   A CB  1 
ATOM   2096 C CG  . PHE   A 1 291 ? 170.436 191.891 181.589 1.00 45.77 ?  291 PHE   A CG  1 
ATOM   2097 C CD1 . PHE   A 1 291 ? 171.208 191.136 182.455 1.00 45.77 ?  291 PHE   A CD1 1 
ATOM   2098 C CD2 . PHE   A 1 291 ? 169.389 192.632 182.107 1.00 45.77 ?  291 PHE   A CD2 1 
ATOM   2099 C CE1 . PHE   A 1 291 ? 170.951 191.133 183.812 1.00 45.77 ?  291 PHE   A CE1 1 
ATOM   2100 C CE2 . PHE   A 1 291 ? 169.127 192.633 183.462 1.00 45.77 ?  291 PHE   A CE2 1 
ATOM   2101 C CZ  . PHE   A 1 291 ? 169.909 191.882 184.316 1.00 45.77 ?  291 PHE   A CZ  1 
ATOM   2102 N N   . LEU   A 1 292 ? 167.919 191.169 178.862 1.00 44.90 ?  292 LEU   A N   1 
ATOM   2103 C CA  . LEU   A 1 292 ? 166.474 191.003 178.986 1.00 44.90 ?  292 LEU   A CA  1 
ATOM   2104 C C   . LEU   A 1 292 ? 166.047 189.599 178.576 1.00 44.90 ?  292 LEU   A C   1 
ATOM   2105 O O   . LEU   A 1 292 ? 165.181 188.993 179.220 1.00 44.90 ?  292 LEU   A O   1 
ATOM   2106 C CB  . LEU   A 1 292 ? 165.747 192.052 178.145 1.00 44.90 ?  292 LEU   A CB  1 
ATOM   2107 C CG  . LEU   A 1 292 ? 165.852 193.512 178.598 1.00 44.90 ?  292 LEU   A CG  1 
ATOM   2108 C CD1 . LEU   A 1 292 ? 164.767 194.345 177.935 1.00 44.90 ?  292 LEU   A CD1 1 
ATOM   2109 C CD2 . LEU   A 1 292 ? 165.774 193.649 180.110 1.00 44.90 ?  292 LEU   A CD2 1 
ATOM   2110 N N   . ALA   A 1 293 ? 166.648 189.060 177.514 1.00 43.32 ?  293 ALA   A N   1 
ATOM   2111 C CA  . ALA   A 1 293 ? 166.324 187.700 177.100 1.00 43.32 ?  293 ALA   A CA  1 
ATOM   2112 C C   . ALA   A 1 293 ? 166.640 186.701 178.205 1.00 43.32 ?  293 ALA   A C   1 
ATOM   2113 O O   . ALA   A 1 293 ? 165.826 185.823 178.510 1.00 43.32 ?  293 ALA   A O   1 
ATOM   2114 C CB  . ALA   A 1 293 ? 167.088 187.347 175.826 1.00 43.32 ?  293 ALA   A CB  1 
ATOM   2115 N N   . TRP   A 1 294 ? 167.815 186.824 178.823 1.00 43.53 ?  294 TRP   A N   1 
ATOM   2116 C CA  . TRP   A 1 294 ? 168.163 185.927 179.919 1.00 43.53 ?  294 TRP   A CA  1 
ATOM   2117 C C   . TRP   A 1 294 ? 167.202 186.101 181.086 1.00 43.53 ?  294 TRP   A C   1 
ATOM   2118 O O   . TRP   A 1 294 ? 166.771 185.117 181.698 1.00 43.53 ?  294 TRP   A O   1 
ATOM   2119 C CB  . TRP   A 1 294 ? 169.602 186.181 180.365 1.00 43.53 ?  294 TRP   A CB  1 
ATOM   2120 C CG  . TRP   A 1 294 ? 169.977 185.476 181.627 1.00 43.53 ?  294 TRP   A CG  1 
ATOM   2121 C CD1 . TRP   A 1 294 ? 170.349 184.173 181.754 1.00 43.53 ?  294 TRP   A CD1 1 
ATOM   2122 C CD2 . TRP   A 1 294 ? 170.026 186.037 182.943 1.00 43.53 ?  294 TRP   A CD2 1 
ATOM   2123 N NE1 . TRP   A 1 294 ? 170.626 183.885 183.067 1.00 43.53 ?  294 TRP   A NE1 1 
ATOM   2124 C CE2 . TRP   A 1 294 ? 170.433 185.014 183.818 1.00 43.53 ?  294 TRP   A CE2 1 
ATOM   2125 C CE3 . TRP   A 1 294 ? 169.764 187.306 183.465 1.00 43.53 ?  294 TRP   A CE3 1 
ATOM   2126 C CZ2 . TRP   A 1 294 ? 170.585 185.219 185.186 1.00 43.53 ?  294 TRP   A CZ2 1 
ATOM   2127 C CZ3 . TRP   A 1 294 ? 169.914 187.508 184.823 1.00 43.53 ?  294 TRP   A CZ3 1 
ATOM   2128 C CH2 . TRP   A 1 294 ? 170.321 186.469 185.668 1.00 43.53 ?  294 TRP   A CH2 1 
ATOM   2129 N N   . ARG   A 1 295 ? 166.848 187.347 181.403 1.00 46.97 ?  295 ARG   A N   1 
ATOM   2130 C CA  . ARG   A 1 295 ? 165.857 187.599 182.440 1.00 46.97 ?  295 ARG   A CA  1 
ATOM   2131 C C   . ARG   A 1 295 ? 164.506 186.996 182.087 1.00 46.97 ?  295 ARG   A C   1 
ATOM   2132 O O   . ARG   A 1 295 ? 163.684 186.776 182.982 1.00 46.97 ?  295 ARG   A O   1 
ATOM   2133 C CB  . ARG   A 1 295 ? 165.715 189.107 182.663 1.00 46.97 ?  295 ARG   A CB  1 
ATOM   2134 C CG  . ARG   A 1 295 ? 165.042 189.500 183.970 1.00 46.97 ?  295 ARG   A CG  1 
ATOM   2135 C CD  . ARG   A 1 295 ? 165.854 189.065 185.180 1.00 46.97 ?  295 ARG   A CD  1 
ATOM   2136 N NE  . ARG   A 1 295 ? 165.401 189.715 186.404 1.00 46.97 ?  295 ARG   A NE  1 
ATOM   2137 C CZ  . ARG   A 1 295 ? 164.329 189.353 187.096 1.00 46.97 ?  295 ARG   A CZ  1 
ATOM   2138 N NH1 . ARG   A 1 295 ? 163.568 188.340 186.715 1.00 46.97 1  295 ARG   A NH1 1 
ATOM   2139 N NH2 . ARG   A 1 295 ? 164.012 190.026 188.199 1.00 46.97 ?  295 ARG   A NH2 1 
ATOM   2140 N N   . ALA   A 1 296 ? 164.258 186.728 180.808 1.00 44.39 ?  296 ALA   A N   1 
ATOM   2141 C CA  . ALA   A 1 296 ? 163.009 186.130 180.358 1.00 44.39 ?  296 ALA   A CA  1 
ATOM   2142 C C   . ALA   A 1 296 ? 163.046 184.607 180.352 1.00 44.39 ?  296 ALA   A C   1 
ATOM   2143 O O   . ALA   A 1 296 ? 162.084 183.981 179.899 1.00 44.39 ?  296 ALA   A O   1 
ATOM   2144 C CB  . ALA   A 1 296 ? 162.660 186.638 178.958 1.00 44.39 ?  296 ALA   A CB  1 
ATOM   2145 N N   . VAL   A 1 297 ? 164.126 183.999 180.835 1.00 43.42 ?  297 VAL   A N   1 
ATOM   2146 C CA  . VAL   A 1 297 ? 164.293 182.551 180.824 1.00 43.42 ?  297 VAL   A CA  1 
ATOM   2147 C C   . VAL   A 1 297 ? 164.533 182.076 182.249 1.00 43.42 ?  297 VAL   A C   1 
ATOM   2148 O O   . VAL   A 1 297 ? 164.994 182.845 183.100 1.00 43.42 ?  297 VAL   A O   1 
ATOM   2149 C CB  . VAL   A 1 297 ? 165.453 182.127 179.902 1.00 43.42 ?  297 VAL   A CB  1 
ATOM   2150 C CG1 . VAL   A 1 297 ? 165.680 180.634 179.985 1.00 43.42 ?  297 VAL   A CG1 1 
ATOM   2151 C CG2 . VAL   A 1 297 ? 165.164 182.534 178.473 1.00 43.42 ?  297 VAL   A CG2 1 
ATOM   2152 N N   . ASN   A 1 298 ? 164.216 180.806 182.508 1.00 42.88 ?  298 ASN   A N   1 
ATOM   2153 C CA  . ASN   A 1 298 ? 164.314 180.243 183.843 1.00 42.88 ?  298 ASN   A CA  1 
ATOM   2154 C C   . ASN   A 1 298 ? 165.000 178.885 183.899 1.00 42.88 ?  298 ASN   A C   1 
ATOM   2155 O O   . ASN   A 1 298 ? 165.384 178.458 184.993 1.00 42.88 ?  298 ASN   A O   1 
ATOM   2156 C CB  . ASN   A 1 298 ? 162.914 180.113 184.461 1.00 42.88 ?  298 ASN   A CB  1 
ATOM   2157 C CG  . ASN   A 1 298 ? 162.298 181.458 184.793 1.00 42.88 ?  298 ASN   A CG  1 
ATOM   2158 O OD1 . ASN   A 1 298 ? 162.972 182.354 185.300 1.00 42.88 ?  298 ASN   A OD1 1 
ATOM   2159 N ND2 . ASN   A 1 298 ? 161.011 181.608 184.501 1.00 42.88 ?  298 ASN   A ND2 1 
ATOM   2160 N N   . ASP   A 1 299 ? 165.168 178.198 182.772 1.00 42.20 ?  299 ASP   A N   1 
ATOM   2161 C CA  . ASP   A 1 299 ? 165.773 176.874 182.754 1.00 42.20 ?  299 ASP   A CA  1 
ATOM   2162 C C   . ASP   A 1 299 ? 167.231 176.952 182.315 1.00 42.20 ?  299 ASP   A C   1 
ATOM   2163 O O   . ASP   A 1 299 ? 167.623 177.833 181.547 1.00 42.20 ?  299 ASP   A O   1 
ATOM   2164 C CB  . ASP   A 1 299 ? 165.004 175.929 181.827 1.00 42.20 ?  299 ASP   A CB  1 
ATOM   2165 C CG  . ASP   A 1 299 ? 165.023 176.381 180.383 1.00 42.20 ?  299 ASP   A CG  1 
ATOM   2166 O OD1 . ASP   A 1 299 ? 165.484 177.507 180.111 1.00 42.20 ?  299 ASP   A OD1 1 
ATOM   2167 O OD2 . ASP   A 1 299 ? 164.582 175.603 179.513 1.00 42.20 -1 299 ASP   A OD2 1 
ATOM   2168 N N   . ARG   A 1 300 ? 168.026 175.997 182.801 1.00 40.32 ?  300 ARG   A N   1 
ATOM   2169 C CA  . ARG   A 1 300 ? 169.468 176.028 182.577 1.00 40.32 ?  300 ARG   A CA  1 
ATOM   2170 C C   . ARG   A 1 300 ? 169.802 176.110 181.092 1.00 40.32 ?  300 ARG   A C   1 
ATOM   2171 O O   . ARG   A 1 300 ? 170.612 176.946 180.668 1.00 40.32 ?  300 ARG   A O   1 
ATOM   2172 C CB  . ARG   A 1 300 ? 170.101 174.787 183.200 1.00 40.32 ?  300 ARG   A CB  1 
ATOM   2173 C CG  . ARG   A 1 300 ? 170.060 174.777 184.714 1.00 40.32 ?  300 ARG   A CG  1 
ATOM   2174 C CD  . ARG   A 1 300 ? 170.845 173.611 185.283 1.00 40.32 ?  300 ARG   A CD  1 
ATOM   2175 N NE  . ARG   A 1 300 ? 170.334 172.334 184.798 1.00 40.32 ?  300 ARG   A NE  1 
ATOM   2176 C CZ  . ARG   A 1 300 ? 170.710 171.150 185.260 1.00 40.32 ?  300 ARG   A CZ  1 
ATOM   2177 N NH1 . ARG   A 1 300 ? 171.607 171.038 186.226 1.00 40.32 1  300 ARG   A NH1 1 
ATOM   2178 N NH2 . ARG   A 1 300 ? 170.170 170.051 184.742 1.00 40.32 ?  300 ARG   A NH2 1 
ATOM   2179 N N   . LEU   A 1 301 ? 169.188 175.244 180.283 1.00 40.77 ?  301 LEU   A N   1 
ATOM   2180 C CA  . LEU   A 1 301 ? 169.521 175.206 178.863 1.00 40.77 ?  301 LEU   A CA  1 
ATOM   2181 C C   . LEU   A 1 301 ? 169.234 176.542 178.194 1.00 40.77 ?  301 LEU   A C   1 
ATOM   2182 O O   . LEU   A 1 301 ? 170.055 177.044 177.419 1.00 40.77 ?  301 LEU   A O   1 
ATOM   2183 C CB  . LEU   A 1 301 ? 168.747 174.088 178.171 1.00 40.77 ?  301 LEU   A CB  1 
ATOM   2184 C CG  . LEU   A 1 301 ? 169.215 173.773 176.749 1.00 40.77 ?  301 LEU   A CG  1 
ATOM   2185 C CD1 . LEU   A 1 301 ? 170.476 172.933 176.775 1.00 40.77 ?  301 LEU   A CD1 1 
ATOM   2186 C CD2 . LEU   A 1 301 ? 168.122 173.067 175.972 1.00 40.77 ?  301 LEU   A CD2 1 
ATOM   2187 N N   . GLY   A 1 302 ? 168.075 177.133 178.476 1.00 42.54 ?  302 GLY   A N   1 
ATOM   2188 C CA  . GLY   A 1 302 ? 167.754 178.415 177.874 1.00 42.54 ?  302 GLY   A CA  1 
ATOM   2189 C C   . GLY   A 1 302 ? 168.713 179.509 178.300 1.00 42.54 ?  302 GLY   A C   1 
ATOM   2190 O O   . GLY   A 1 302 ? 169.129 180.336 177.482 1.00 42.54 ?  302 GLY   A O   1 
ATOM   2191 N N   . GLN   A 1 303 ? 169.079 179.532 179.583 1.00 42.13 ?  303 GLN   A N   1 
ATOM   2192 C CA  . GLN   A 1 303 ? 170.015 180.542 180.065 1.00 42.13 ?  303 GLN   A CA  1 
ATOM   2193 C C   . GLN   A 1 303 ? 171.357 180.425 179.355 1.00 42.13 ?  303 GLN   A C   1 
ATOM   2194 O O   . GLN   A 1 303 ? 171.905 181.424 178.872 1.00 42.13 ?  303 GLN   A O   1 
ATOM   2195 C CB  . GLN   A 1 303 ? 170.197 180.410 181.577 1.00 42.13 ?  303 GLN   A CB  1 
ATOM   2196 C CG  . GLN   A 1 303 ? 168.912 180.515 182.377 1.00 42.13 ?  303 GLN   A CG  1 
ATOM   2197 C CD  . GLN   A 1 303 ? 169.114 181.175 183.725 1.00 42.13 ?  303 GLN   A CD  1 
ATOM   2198 O OE1 . GLN   A 1 303 ? 168.517 182.211 184.016 1.00 42.13 ?  303 GLN   A OE1 1 
ATOM   2199 N NE2 . GLN   A 1 303 ? 169.968 180.584 184.552 1.00 42.13 ?  303 GLN   A NE2 1 
ATOM   2200 N N   . ILE   A 1 304 ? 171.901 179.209 179.275 1.00 40.76 ?  304 ILE   A N   1 
ATOM   2201 C CA  . ILE   A 1 304 ? 173.201 179.041 178.634 1.00 40.76 ?  304 ILE   A CA  1 
ATOM   2202 C C   . ILE   A 1 304 ? 173.106 179.356 177.147 1.00 40.76 ?  304 ILE   A C   1 
ATOM   2203 O O   . ILE   A 1 304 ? 174.031 179.931 176.561 1.00 40.76 ?  304 ILE   A O   1 
ATOM   2204 C CB  . ILE   A 1 304 ? 173.753 177.625 178.886 1.00 40.76 ?  304 ILE   A CB  1 
ATOM   2205 C CG1 . ILE   A 1 304 ? 175.189 177.505 178.371 1.00 40.76 ?  304 ILE   A CG1 1 
ATOM   2206 C CG2 . ILE   A 1 304 ? 172.878 176.573 178.233 1.00 40.76 ?  304 ILE   A CG2 1 
ATOM   2207 C CD1 . ILE   A 1 304 ? 176.176 178.376 179.107 1.00 40.76 ?  304 ILE   A CD1 1 
ATOM   2208 N N   . CYS   A 1 305 ? 171.990 178.992 176.510 1.00 41.76 ?  305 CYS   A N   1 
ATOM   2209 C CA  . CYS   A 1 305 ? 171.834 179.274 175.088 1.00 41.76 ?  305 CYS   A CA  1 
ATOM   2210 C C   . CYS   A 1 305 ? 171.788 180.772 174.825 1.00 41.76 ?  305 CYS   A C   1 
ATOM   2211 O O   . CYS   A 1 305 ? 172.384 181.254 173.859 1.00 41.76 ?  305 CYS   A O   1 
ATOM   2212 C CB  . CYS   A 1 305 ? 170.577 178.595 174.554 1.00 41.76 ?  305 CYS   A CB  1 
ATOM   2213 S SG  . CYS   A 1 305 ? 170.767 176.822 174.284 1.00 41.76 ?  305 CYS   A SG  1 
ATOM   2214 N N   . VAL   A 1 306 ? 171.085 181.528 175.671 1.00 42.26 ?  306 VAL   A N   1 
ATOM   2215 C CA  . VAL   A 1 306 ? 171.064 182.980 175.511 1.00 42.26 ?  306 VAL   A CA  1 
ATOM   2216 C C   . VAL   A 1 306 ? 172.451 183.564 175.752 1.00 42.26 ?  306 VAL   A C   1 
ATOM   2217 O O   . VAL   A 1 306 ? 172.904 184.455 175.018 1.00 42.26 ?  306 VAL   A O   1 
ATOM   2218 C CB  . VAL   A 1 306 ? 170.020 183.608 176.450 1.00 42.26 ?  306 VAL   A CB  1 
ATOM   2219 C CG1 . VAL   A 1 306 ? 170.206 185.115 176.514 1.00 42.26 ?  306 VAL   A CG1 1 
ATOM   2220 C CG2 . VAL   A 1 306 ? 168.619 183.259 175.987 1.00 42.26 ?  306 VAL   A CG2 1 
ATOM   2221 N N   . VAL   A 1 307 ? 173.145 183.083 176.785 1.00 41.41 ?  307 VAL   A N   1 
ATOM   2222 C CA  . VAL   A 1 307 ? 174.479 183.599 177.071 1.00 41.41 ?  307 VAL   A CA  1 
ATOM   2223 C C   . VAL   A 1 307 ? 175.400 183.377 175.880 1.00 41.41 ?  307 VAL   A C   1 
ATOM   2224 O O   . VAL   A 1 307 ? 176.146 184.276 175.479 1.00 41.41 ?  307 VAL   A O   1 
ATOM   2225 C CB  . VAL   A 1 307 ? 175.038 182.952 178.350 1.00 41.41 ?  307 VAL   A CB  1 
ATOM   2226 C CG1 . VAL   A 1 307 ? 176.540 183.167 178.442 1.00 41.41 ?  307 VAL   A CG1 1 
ATOM   2227 C CG2 . VAL   A 1 307 ? 174.339 183.520 179.573 1.00 41.41 ?  307 VAL   A CG2 1 
ATOM   2228 N N   . GLU   A 1 308 ? 175.358 182.187 175.289 1.00 41.84 ?  308 GLU   A N   1 
ATOM   2229 C CA  . GLU   A 1 308 ? 176.207 181.894 174.143 1.00 41.84 ?  308 GLU   A CA  1 
ATOM   2230 C C   . GLU   A 1 308 ? 175.757 182.599 172.871 1.00 41.84 ?  308 GLU   A C   1 
ATOM   2231 O O   . GLU   A 1 308 ? 176.606 182.951 172.045 1.00 41.84 ?  308 GLU   A O   1 
ATOM   2232 C CB  . GLU   A 1 308 ? 176.266 180.386 173.911 1.00 41.84 ?  308 GLU   A CB  1 
ATOM   2233 C CG  . GLU   A 1 308 ? 176.972 179.655 175.032 1.00 41.84 ?  308 GLU   A CG  1 
ATOM   2234 C CD  . GLU   A 1 308 ? 178.479 179.758 174.923 1.00 41.84 ?  308 GLU   A CD  1 
ATOM   2235 O OE1 . GLU   A 1 308 ? 178.971 180.746 174.339 1.00 41.84 ?  308 GLU   A OE1 1 
ATOM   2236 O OE2 . GLU   A 1 308 ? 179.177 178.852 175.424 1.00 41.84 -1 308 GLU   A OE2 1 
ATOM   2237 N N   . MET   A 1 309 ? 174.456 182.825 172.695 1.00 43.40 ?  309 MET   A N   1 
ATOM   2238 C CA  . MET   A 1 309 ? 173.987 183.663 171.602 1.00 43.40 ?  309 MET   A CA  1 
ATOM   2239 C C   . MET   A 1 309 ? 174.549 185.068 171.696 1.00 43.40 ?  309 MET   A C   1 
ATOM   2240 O O   . MET   A 1 309 ? 174.934 185.641 170.673 1.00 43.40 ?  309 MET   A O   1 
ATOM   2241 C CB  . MET   A 1 309 ? 172.457 183.717 171.606 1.00 43.40 ?  309 MET   A CB  1 
ATOM   2242 C CG  . MET   A 1 309 ? 171.855 184.856 170.790 1.00 43.40 ?  309 MET   A CG  1 
ATOM   2243 S SD  . MET   A 1 309 ? 170.052 184.816 170.772 1.00 43.40 ?  309 MET   A SD  1 
ATOM   2244 C CE  . MET   A 1 309 ? 169.746 183.265 169.934 1.00 43.40 ?  309 MET   A CE  1 
ATOM   2245 N N   . PHE   A 1 310 ? 174.598 185.634 172.898 1.00 43.01 ?  310 PHE   A N   1 
ATOM   2246 C CA  . PHE   A 1 310 ? 175.244 186.924 173.095 1.00 43.01 ?  310 PHE   A CA  1 
ATOM   2247 C C   . PHE   A 1 310 ? 176.749 186.858 172.863 1.00 43.01 ?  310 PHE   A C   1 
ATOM   2248 O O   . PHE   A 1 310 ? 177.328 187.762 172.250 1.00 43.01 ?  310 PHE   A O   1 
ATOM   2249 C CB  . PHE   A 1 310 ? 174.944 187.442 174.500 1.00 43.01 ?  310 PHE   A CB  1 
ATOM   2250 C CG  . PHE   A 1 310 ? 175.545 188.776 174.780 1.00 43.01 ?  310 PHE   A CG  1 
ATOM   2251 C CD1 . PHE   A 1 310 ? 174.994 189.919 174.242 1.00 43.01 ?  310 PHE   A CD1 1 
ATOM   2252 C CD2 . PHE   A 1 310 ? 176.641 188.892 175.615 1.00 43.01 ?  310 PHE   A CD2 1 
ATOM   2253 C CE1 . PHE   A 1 310 ? 175.547 191.146 174.493 1.00 43.01 ?  310 PHE   A CE1 1 
ATOM   2254 C CE2 . PHE   A 1 310 ? 177.191 190.124 175.883 1.00 43.01 ?  310 PHE   A CE2 1 
ATOM   2255 C CZ  . PHE   A 1 310 ? 176.637 191.255 175.328 1.00 43.01 ?  310 PHE   A CZ  1 
ATOM   2256 N N   . GLY   A 1 311 ? 177.392 185.798 173.349 1.00 42.21 ?  311 GLY   A N   1 
ATOM   2257 C CA  . GLY   A 1 311 ? 178.825 185.662 173.148 1.00 42.21 ?  311 GLY   A CA  1 
ATOM   2258 C C   . GLY   A 1 311 ? 179.197 185.609 171.681 1.00 42.21 ?  311 GLY   A C   1 
ATOM   2259 O O   . GLY   A 1 311 ? 180.193 186.200 171.259 1.00 42.21 ?  311 GLY   A O   1 
ATOM   2260 N N   . LEU   A 1 312 ? 178.399 184.898 170.883 1.00 40.66 ?  312 LEU   A N   1 
ATOM   2261 C CA  . LEU   A 1 312 ? 178.655 184.826 169.450 1.00 40.66 ?  312 LEU   A CA  1 
ATOM   2262 C C   . LEU   A 1 312 ? 178.512 186.187 168.787 1.00 40.66 ?  312 LEU   A C   1 
ATOM   2263 O O   . LEU   A 1 312 ? 179.093 186.419 167.721 1.00 40.66 ?  312 LEU   A O   1 
ATOM   2264 C CB  . LEU   A 1 312 ? 177.701 183.828 168.800 1.00 40.66 ?  312 LEU   A CB  1 
ATOM   2265 C CG  . LEU   A 1 312 ? 177.943 182.374 169.191 1.00 40.66 ?  312 LEU   A CG  1 
ATOM   2266 C CD1 . LEU   A 1 312 ? 176.660 181.575 169.066 1.00 40.66 ?  312 LEU   A CD1 1 
ATOM   2267 C CD2 . LEU   A 1 312 ? 179.046 181.776 168.340 1.00 40.66 ?  312 LEU   A CD2 1 
ATOM   2268 N N   . LEU   A 1 313 ? 177.743 187.093 169.392 1.00 41.16 ?  313 LEU   A N   1 
ATOM   2269 C CA  . LEU   A 1 313 ? 177.525 188.406 168.805 1.00 41.16 ?  313 LEU   A CA  1 
ATOM   2270 C C   . LEU   A 1 313 ? 178.548 189.436 169.260 1.00 41.16 ?  313 LEU   A C   1 
ATOM   2271 O O   . LEU   A 1 313 ? 178.848 190.363 168.501 1.00 41.16 ?  313 LEU   A O   1 
ATOM   2272 C CB  . LEU   A 1 313 ? 176.118 188.906 169.142 1.00 41.16 ?  313 LEU   A CB  1 
ATOM   2273 C CG  . LEU   A 1 313 ? 174.973 188.378 168.276 1.00 41.16 ?  313 LEU   A CG  1 
ATOM   2274 C CD1 . LEU   A 1 313 ? 173.639 188.855 168.819 1.00 41.16 ?  313 LEU   A CD1 1 
ATOM   2275 C CD2 . LEU   A 1 313 ? 175.137 188.807 166.830 1.00 41.16 ?  313 LEU   A CD2 1 
ATOM   2276 N N   . ILE   A 1 314 ? 179.090 189.308 170.469 1.00 42.94 ?  314 ILE   A N   1 
ATOM   2277 C CA  . ILE   A 1 314 ? 180.038 190.293 170.973 1.00 42.94 ?  314 ILE   A CA  1 
ATOM   2278 C C   . ILE   A 1 314 ? 181.483 189.963 170.627 1.00 42.94 ?  314 ILE   A C   1 
ATOM   2279 O O   . ILE   A 1 314 ? 182.297 190.892 170.516 1.00 42.94 ?  314 ILE   A O   1 
ATOM   2280 C CB  . ILE   A 1 314 ? 179.899 190.492 172.496 1.00 42.94 ?  314 ILE   A CB  1 
ATOM   2281 C CG1 . ILE   A 1 314 ? 180.207 189.194 173.249 1.00 42.94 ?  314 ILE   A CG1 1 
ATOM   2282 C CG2 . ILE   A 1 314 ? 178.514 191.001 172.827 1.00 42.94 ?  314 ILE   A CG2 1 
ATOM   2283 C CD1 . ILE   A 1 314 ? 180.445 189.395 174.727 1.00 42.94 ?  314 ILE   A CD1 1 
ATOM   2284 N N   . SER   A 1 315 ? 181.834 188.693 170.458 1.00 42.17 ?  315 SER   A N   1 
ATOM   2285 C CA  . SER   A 1 315 ? 183.223 188.363 170.199 1.00 42.17 ?  315 SER   A CA  1 
ATOM   2286 C C   . SER   A 1 315 ? 183.676 189.044 168.909 1.00 42.17 ?  315 SER   A C   1 
ATOM   2287 O O   . SER   A 1 315 ? 182.934 189.077 167.923 1.00 42.17 ?  315 SER   A O   1 
ATOM   2288 C CB  . SER   A 1 315 ? 183.408 186.851 170.092 1.00 42.17 ?  315 SER   A CB  1 
ATOM   2289 O OG  . SER   A 1 315 ? 182.752 186.333 168.950 1.00 42.17 ?  315 SER   A OG  1 
ATOM   2290 N N   . PRO   A 1 316 ? 184.887 189.608 168.887 1.00 42.42 ?  316 PRO   A N   1 
ATOM   2291 C CA  . PRO   A 1 316 ? 185.326 190.316 167.675 1.00 42.42 ?  316 PRO   A CA  1 
ATOM   2292 C C   . PRO   A 1 316 ? 185.288 189.444 166.437 1.00 42.42 ?  316 PRO   A C   1 
ATOM   2293 O O   . PRO   A 1 316 ? 184.929 189.928 165.358 1.00 42.42 ?  316 PRO   A O   1 
ATOM   2294 C CB  . PRO   A 1 316 ? 186.757 190.752 168.021 1.00 42.42 ?  316 PRO   A CB  1 
ATOM   2295 C CG  . PRO   A 1 316 ? 187.185 189.840 169.118 1.00 42.42 ?  316 PRO   A CG  1 
ATOM   2296 C CD  . PRO   A 1 316 ? 185.951 189.546 169.903 1.00 42.42 ?  316 PRO   A CD  1 
ATOM   2297 N N   . ILE   A 1 317 ? 185.631 188.166 166.567 1.00 42.24 ?  317 ILE   A N   1 
ATOM   2298 C CA  . ILE   A 1 317 ? 185.615 187.217 165.462 1.00 42.24 ?  317 ILE   A CA  1 
ATOM   2299 C C   . ILE   A 1 317 ? 184.689 186.080 165.867 1.00 42.24 ?  317 ILE   A C   1 
ATOM   2300 O O   . ILE   A 1 317 ? 184.982 185.349 166.820 1.00 42.24 ?  317 ILE   A O   1 
ATOM   2301 C CB  . ILE   A 1 317 ? 187.013 186.674 165.138 1.00 42.24 ?  317 ILE   A CB  1 
ATOM   2302 C CG1 . ILE   A 1 317 ? 187.959 187.794 164.694 1.00 42.24 ?  317 ILE   A CG1 1 
ATOM   2303 C CG2 . ILE   A 1 317 ? 186.929 185.620 164.064 1.00 42.24 ?  317 ILE   A CG2 1 
ATOM   2304 C CD1 . ILE   A 1 317 ? 187.374 188.754 163.680 1.00 42.24 ?  317 ILE   A CD1 1 
ATOM   2305 N N   . SER   A 1 318 ? 183.576 185.925 165.153 1.00 40.00 ?  318 SER   A N   1 
ATOM   2306 C CA  . SER   A 1 318 ? 182.654 184.807 165.354 1.00 40.00 ?  318 SER   A CA  1 
ATOM   2307 C C   . SER   A 1 318 ? 182.276 184.284 163.974 1.00 40.00 ?  318 SER   A C   1 
ATOM   2308 O O   . SER   A 1 318 ? 181.266 184.698 163.401 1.00 40.00 ?  318 SER   A O   1 
ATOM   2309 C CB  . SER   A 1 318 ? 181.426 185.232 166.153 1.00 40.00 ?  318 SER   A CB  1 
ATOM   2310 O OG  . SER   A 1 318 ? 180.525 185.977 165.353 1.00 40.00 ?  318 SER   A OG  1 
ATOM   2311 N N   . TRP   A 1 319 ? 183.077 183.365 163.446 1.00 40.47 ?  319 TRP   A N   1 
ATOM   2312 C CA  . TRP   A 1 319 ? 182.773 182.790 162.148 1.00 40.47 ?  319 TRP   A CA  1 
ATOM   2313 C C   . TRP   A 1 319 ? 181.484 181.981 162.239 1.00 40.47 ?  319 TRP   A C   1 
ATOM   2314 O O   . TRP   A 1 319 ? 180.895 181.811 163.308 1.00 40.47 ?  319 TRP   A O   1 
ATOM   2315 C CB  . TRP   A 1 319 ? 183.922 181.910 161.662 1.00 40.47 ?  319 TRP   A CB  1 
ATOM   2316 C CG  . TRP   A 1 319 ? 185.282 182.480 161.890 1.00 40.47 ?  319 TRP   A CG  1 
ATOM   2317 C CD1 . TRP   A 1 319 ? 186.130 182.183 162.912 1.00 40.47 ?  319 TRP   A CD1 1 
ATOM   2318 C CD2 . TRP   A 1 319 ? 185.953 183.447 161.079 1.00 40.47 ?  319 TRP   A CD2 1 
ATOM   2319 N NE1 . TRP   A 1 319 ? 187.291 182.902 162.786 1.00 40.47 ?  319 TRP   A NE1 1 
ATOM   2320 C CE2 . TRP   A 1 319 ? 187.207 183.686 161.667 1.00 40.47 ?  319 TRP   A CE2 1 
ATOM   2321 C CE3 . TRP   A 1 319 ? 185.616 184.133 159.911 1.00 40.47 ?  319 TRP   A CE3 1 
ATOM   2322 C CZ2 . TRP   A 1 319 ? 188.121 184.584 161.132 1.00 40.47 ?  319 TRP   A CZ2 1 
ATOM   2323 C CZ3 . TRP   A 1 319 ? 186.526 185.021 159.381 1.00 40.47 ?  319 TRP   A CZ3 1 
ATOM   2324 C CH2 . TRP   A 1 319 ? 187.763 185.239 159.989 1.00 40.47 ?  319 TRP   A CH2 1 
ATOM   2325 N N   . THR   A 1 320 ? 181.037 181.470 161.093 1.00 40.12 ?  320 THR   A N   1 
ATOM   2326 C CA  . THR   A 1 320 ? 179.844 180.634 161.093 1.00 40.12 ?  320 THR   A CA  1 
ATOM   2327 C C   . THR   A 1 320 ? 180.059 179.379 161.927 1.00 40.12 ?  320 THR   A C   1 
ATOM   2328 O O   . THR   A 1 320 ? 179.176 178.974 162.690 1.00 40.12 ?  320 THR   A O   1 
ATOM   2329 C CB  . THR   A 1 320 ? 179.456 180.264 159.663 1.00 40.12 ?  320 THR   A CB  1 
ATOM   2330 O OG1 . THR   A 1 320 ? 180.557 179.609 159.020 1.00 40.12 ?  320 THR   A OG1 1 
ATOM   2331 C CG2 . THR   A 1 320 ? 179.074 181.507 158.877 1.00 40.12 ?  320 THR   A CG2 1 
ATOM   2332 N N   . HIS   A 1 321 ? 181.234 178.757 161.810 1.00 39.92 ?  321 HIS   A N   1 
ATOM   2333 C CA  . HIS   A 1 321 ? 181.489 177.532 162.557 1.00 39.92 ?  321 HIS   A CA  1 
ATOM   2334 C C   . HIS   A 1 321 ? 181.512 177.759 164.060 1.00 39.92 ?  321 HIS   A C   1 
ATOM   2335 O O   . HIS   A 1 321 ? 181.465 176.783 164.814 1.00 39.92 ?  321 HIS   A O   1 
ATOM   2336 C CB  . HIS   A 1 321 ? 182.805 176.886 162.109 1.00 39.92 ?  321 HIS   A CB  1 
ATOM   2337 C CG  . HIS   A 1 321 ? 184.011 177.749 162.297 1.00 39.92 ?  321 HIS   A CG  1 
ATOM   2338 N ND1 . HIS   A 1 321 ? 184.295 178.818 161.477 1.00 39.92 ?  321 HIS   A ND1 1 
ATOM   2339 C CD2 . HIS   A 1 321 ? 184.990 177.717 163.229 1.00 39.92 ?  321 HIS   A CD2 1 
ATOM   2340 C CE1 . HIS   A 1 321 ? 185.407 179.400 161.888 1.00 39.92 ?  321 HIS   A CE1 1 
ATOM   2341 N NE2 . HIS   A 1 321 ? 185.849 178.752 162.949 1.00 39.92 ?  321 HIS   A NE2 1 
ATOM   2342 N N   . HIS   A 1 322 ? 181.590 179.010 164.514 1.00 39.78 ?  322 HIS   A N   1 
ATOM   2343 C CA  . HIS   A 1 322 ? 181.442 179.286 165.936 1.00 39.78 ?  322 HIS   A CA  1 
ATOM   2344 C C   . HIS   A 1 322 ? 179.994 179.177 166.388 1.00 39.78 ?  322 HIS   A C   1 
ATOM   2345 O O   . HIS   A 1 322 ? 179.747 178.921 167.571 1.00 39.78 ?  322 HIS   A O   1 
ATOM   2346 C CB  . HIS   A 1 322 ? 181.975 180.681 166.265 1.00 39.78 ?  322 HIS   A CB  1 
ATOM   2347 C CG  . HIS   A 1 322 ? 183.468 180.768 166.290 1.00 39.78 ?  322 HIS   A CG  1 
ATOM   2348 N ND1 . HIS   A 1 322 ? 184.141 181.842 166.831 1.00 39.78 ?  322 HIS   A ND1 1 
ATOM   2349 C CD2 . HIS   A 1 322 ? 184.420 179.919 165.837 1.00 39.78 ?  322 HIS   A CD2 1 
ATOM   2350 C CE1 . HIS   A 1 322 ? 185.442 181.651 166.712 1.00 39.78 ?  322 HIS   A CE1 1 
ATOM   2351 N NE2 . HIS   A 1 322 ? 185.638 180.491 166.111 1.00 39.78 ?  322 HIS   A NE2 1 
ATOM   2352 N N   . TRP   A 1 323 ? 179.034 179.362 165.481 1.00 39.32 ?  323 TRP   A N   1 
ATOM   2353 C CA  . TRP   A 1 323 ? 177.631 179.395 165.869 1.00 39.32 ?  323 TRP   A CA  1 
ATOM   2354 C C   . TRP   A 1 323 ? 177.061 177.989 165.978 1.00 39.32 ?  323 TRP   A C   1 
ATOM   2355 O O   . TRP   A 1 323 ? 175.970 177.722 165.468 1.00 39.32 ?  323 TRP   A O   1 
ATOM   2356 C CB  . TRP   A 1 323 ? 176.805 180.196 164.854 1.00 39.32 ?  323 TRP   A CB  1 
ATOM   2357 C CG  . TRP   A 1 323 ? 177.095 181.664 164.833 1.00 39.32 ?  323 TRP   A CG  1 
ATOM   2358 C CD1 . TRP   A 1 323 ? 178.315 182.253 164.718 1.00 39.32 ?  323 TRP   A CD1 1 
ATOM   2359 C CD2 . TRP   A 1 323 ? 176.144 182.729 164.925 1.00 39.32 ?  323 TRP   A CD2 1 
ATOM   2360 N NE1 . TRP   A 1 323 ? 178.187 183.620 164.731 1.00 39.32 ?  323 TRP   A NE1 1 
ATOM   2361 C CE2 . TRP   A 1 323 ? 176.861 183.936 164.860 1.00 39.32 ?  323 TRP   A CE2 1 
ATOM   2362 C CE3 . TRP   A 1 323 ? 174.757 182.779 165.057 1.00 39.32 ?  323 TRP   A CE3 1 
ATOM   2363 C CZ2 . TRP   A 1 323 ? 176.239 185.176 164.924 1.00 39.32 ?  323 TRP   A CZ2 1 
ATOM   2364 C CZ3 . TRP   A 1 323 ? 174.142 184.012 165.120 1.00 39.32 ?  323 TRP   A CZ3 1 
ATOM   2365 C CH2 . TRP   A 1 323 ? 174.882 185.194 165.054 1.00 39.32 ?  323 TRP   A CH2 1 
ATOM   2366 N N   . VAL   A 1 324 ? 177.767 177.088 166.660 1.00 40.10 ?  324 VAL   A N   1 
ATOM   2367 C CA  . VAL   A 1 324 ? 177.208 175.763 166.898 1.00 40.10 ?  324 VAL   A CA  1 
ATOM   2368 C C   . VAL   A 1 324 ? 176.345 175.769 168.148 1.00 40.10 ?  324 VAL   A C   1 
ATOM   2369 O O   . VAL   A 1 324 ? 175.572 174.830 168.369 1.00 40.10 ?  324 VAL   A O   1 
ATOM   2370 C CB  . VAL   A 1 324 ? 178.316 174.703 167.006 1.00 40.10 ?  324 VAL   A CB  1 
ATOM   2371 C CG1 . VAL   A 1 324 ? 177.717 173.321 167.187 1.00 40.10 ?  324 VAL   A CG1 1 
ATOM   2372 C CG2 . VAL   A 1 324 ? 179.189 174.738 165.777 1.00 40.10 ?  324 VAL   A CG2 1 
ATOM   2373 N N   . TRP   A 1 325 ? 176.452 176.817 168.963 1.00 40.67 ?  325 TRP   A N   1 
ATOM   2374 C CA  . TRP   A 1 325 ? 175.604 176.978 170.132 1.00 40.67 ?  325 TRP   A CA  1 
ATOM   2375 C C   . TRP   A 1 325 ? 174.146 177.206 169.768 1.00 40.67 ?  325 TRP   A C   1 
ATOM   2376 O O   . TRP   A 1 325 ? 173.284 177.095 170.645 1.00 40.67 ?  325 TRP   A O   1 
ATOM   2377 C CB  . TRP   A 1 325 ? 176.127 178.139 170.974 1.00 40.67 ?  325 TRP   A CB  1 
ATOM   2378 C CG  . TRP   A 1 325 ? 177.130 177.709 171.982 1.00 40.67 ?  325 TRP   A CG  1 
ATOM   2379 C CD1 . TRP   A 1 325 ? 178.434 178.095 172.054 1.00 40.67 ?  325 TRP   A CD1 1 
ATOM   2380 C CD2 . TRP   A 1 325 ? 176.914 176.816 173.077 1.00 40.67 ?  325 TRP   A CD2 1 
ATOM   2381 N NE1 . TRP   A 1 325 ? 179.048 177.490 173.120 1.00 40.67 ?  325 TRP   A NE1 1 
ATOM   2382 C CE2 . TRP   A 1 325 ? 178.134 176.701 173.767 1.00 40.67 ?  325 TRP   A CE2 1 
ATOM   2383 C CE3 . TRP   A 1 325 ? 175.808 176.100 173.541 1.00 40.67 ?  325 TRP   A CE3 1 
ATOM   2384 C CZ2 . TRP   A 1 325 ? 178.279 175.904 174.895 1.00 40.67 ?  325 TRP   A CZ2 1 
ATOM   2385 C CZ3 . TRP   A 1 325 ? 175.955 175.308 174.660 1.00 40.67 ?  325 TRP   A CZ3 1 
ATOM   2386 C CH2 . TRP   A 1 325 ? 177.181 175.216 175.324 1.00 40.67 ?  325 TRP   A CH2 1 
ATOM   2387 N N   . MET   A 1 326 ? 173.848 177.517 168.505 1.00 41.29 ?  326 MET   A N   1 
ATOM   2388 C CA  . MET   A 1 326 ? 172.456 177.639 168.096 1.00 41.29 ?  326 MET   A CA  1 
ATOM   2389 C C   . MET   A 1 326 ? 171.740 176.301 168.134 1.00 41.29 ?  326 MET   A C   1 
ATOM   2390 O O   . MET   A 1 326 ? 170.530 176.269 168.351 1.00 41.29 ?  326 MET   A O   1 
ATOM   2391 C CB  . MET   A 1 326 ? 172.351 178.248 166.697 1.00 41.29 ?  326 MET   A CB  1 
ATOM   2392 C CG  . MET   A 1 326 ? 172.845 179.675 166.627 1.00 41.29 ?  326 MET   A CG  1 
ATOM   2393 S SD  . MET   A 1 326 ? 171.818 180.740 167.650 1.00 41.29 ?  326 MET   A SD  1 
ATOM   2394 C CE  . MET   A 1 326 ? 172.738 182.265 167.580 1.00 41.29 ?  326 MET   A CE  1 
ATOM   2395 N N   . VAL   A 1 327 ? 172.449 175.194 167.919 1.00 40.84 ?  327 VAL   A N   1 
ATOM   2396 C CA  . VAL   A 1 327 ? 171.791 173.887 167.942 1.00 40.84 ?  327 VAL   A CA  1 
ATOM   2397 C C   . VAL   A 1 327 ? 171.143 173.614 169.294 1.00 40.84 ?  327 VAL   A C   1 
ATOM   2398 O O   . VAL   A 1 327 ? 169.957 173.242 169.323 1.00 40.84 ?  327 VAL   A O   1 
ATOM   2399 C CB  . VAL   A 1 327 ? 172.786 172.787 167.529 1.00 40.84 ?  327 VAL   A CB  1 
ATOM   2400 C CG1 . VAL   A 1 327 ? 172.210 171.420 167.843 1.00 40.84 ?  327 VAL   A CG1 1 
ATOM   2401 C CG2 . VAL   A 1 327 ? 173.106 172.895 166.052 1.00 40.84 ?  327 VAL   A CG2 1 
ATOM   2402 N N   . PRO   A 1 328 ? 171.830 173.769 170.427 1.00 40.38 ?  328 PRO   A N   1 
ATOM   2403 C CA  . PRO   A 1 328 ? 171.119 173.684 171.709 1.00 40.38 ?  328 PRO   A CA  1 
ATOM   2404 C C   . PRO   A 1 328 ? 169.998 174.697 171.827 1.00 40.38 ?  328 PRO   A C   1 
ATOM   2405 O O   . PRO   A 1 328 ? 168.989 174.418 172.483 1.00 40.38 ?  328 PRO   A O   1 
ATOM   2406 C CB  . PRO   A 1 328 ? 172.229 173.934 172.736 1.00 40.38 ?  328 PRO   A CB  1 
ATOM   2407 C CG  . PRO   A 1 328 ? 173.456 173.454 172.068 1.00 40.38 ?  328 PRO   A CG  1 
ATOM   2408 C CD  . PRO   A 1 328 ? 173.289 173.800 170.619 1.00 40.38 ?  328 PRO   A CD  1 
ATOM   2409 N N   . PHE   A 1 329 ? 170.137 175.870 171.210 1.00 42.19 ?  329 PHE   A N   1 
ATOM   2410 C CA  . PHE   A 1 329 ? 169.067 176.859 171.277 1.00 42.19 ?  329 PHE   A CA  1 
ATOM   2411 C C   . PHE   A 1 329 ? 167.812 176.370 170.562 1.00 42.19 ?  329 PHE   A C   1 
ATOM   2412 O O   . PHE   A 1 329 ? 166.698 176.549 171.063 1.00 42.19 ?  329 PHE   A O   1 
ATOM   2413 C CB  . PHE   A 1 329 ? 169.538 178.185 170.688 1.00 42.19 ?  329 PHE   A CB  1 
ATOM   2414 C CG  . PHE   A 1 329 ? 168.552 179.295 170.856 1.00 42.19 ?  329 PHE   A CG  1 
ATOM   2415 C CD1 . PHE   A 1 329 ? 168.147 179.689 172.119 1.00 42.19 ?  329 PHE   A CD1 1 
ATOM   2416 C CD2 . PHE   A 1 329 ? 168.027 179.944 169.757 1.00 42.19 ?  329 PHE   A CD2 1 
ATOM   2417 C CE1 . PHE   A 1 329 ? 167.235 180.708 172.283 1.00 42.19 ?  329 PHE   A CE1 1 
ATOM   2418 C CE2 . PHE   A 1 329 ? 167.116 180.964 169.914 1.00 42.19 ?  329 PHE   A CE2 1 
ATOM   2419 C CZ  . PHE   A 1 329 ? 166.719 181.348 171.180 1.00 42.19 ?  329 PHE   A CZ  1 
ATOM   2420 N N   . MET   A 1 330 ? 167.968 175.758 169.388 1.00 41.36 ?  330 MET   A N   1 
ATOM   2421 C CA  . MET   A 1 330 ? 166.813 175.210 168.687 1.00 41.36 ?  330 MET   A CA  1 
ATOM   2422 C C   . MET   A 1 330 ? 166.230 174.033 169.453 1.00 41.36 ?  330 MET   A C   1 
ATOM   2423 O O   . MET   A 1 330 ? 165.007 173.845 169.478 1.00 41.36 ?  330 MET   A O   1 
ATOM   2424 C CB  . MET   A 1 330 ? 167.191 174.788 167.267 1.00 41.36 ?  330 MET   A CB  1 
ATOM   2425 C CG  . MET   A 1 330 ? 168.150 175.727 166.567 1.00 41.36 ?  330 MET   A CG  1 
ATOM   2426 S SD  . MET   A 1 330 ? 168.148 175.534 164.779 1.00 41.36 ?  330 MET   A SD  1 
ATOM   2427 C CE  . MET   A 1 330 ? 169.093 174.023 164.611 1.00 41.36 ?  330 MET   A CE  1 
ATOM   2428 N N   . VAL   A 1 331 ? 167.086 173.226 170.082 1.00 40.94 ?  331 VAL   A N   1 
ATOM   2429 C CA  . VAL   A 1 331 ? 166.570 172.148 170.919 1.00 40.94 ?  331 VAL   A CA  1 
ATOM   2430 C C   . VAL   A 1 331 ? 165.719 172.725 172.039 1.00 40.94 ?  331 VAL   A C   1 
ATOM   2431 O O   . VAL   A 1 331 ? 164.636 172.213 172.344 1.00 40.94 ?  331 VAL   A O   1 
ATOM   2432 C CB  . VAL   A 1 331 ? 167.721 171.287 171.467 1.00 40.94 ?  331 VAL   A CB  1 
ATOM   2433 C CG1 . VAL   A 1 331 ? 167.193 170.303 172.495 1.00 40.94 ?  331 VAL   A CG1 1 
ATOM   2434 C CG2 . VAL   A 1 331 ? 168.412 170.550 170.334 1.00 40.94 ?  331 VAL   A CG2 1 
ATOM   2435 N N   . TRP   A 1 332 ? 166.188 173.805 172.662 1.00 41.16 ?  332 TRP   A N   1 
ATOM   2436 C CA  . TRP   A 1 332 ? 165.406 174.464 173.702 1.00 41.16 ?  332 TRP   A CA  1 
ATOM   2437 C C   . TRP   A 1 332 ? 164.087 174.988 173.150 1.00 41.16 ?  332 TRP   A C   1 
ATOM   2438 O O   . TRP   A 1 332 ? 163.032 174.816 173.771 1.00 41.16 ?  332 TRP   A O   1 
ATOM   2439 C CB  . TRP   A 1 332 ? 166.219 175.606 174.309 1.00 41.16 ?  332 TRP   A CB  1 
ATOM   2440 C CG  . TRP   A 1 332 ? 165.477 176.411 175.320 1.00 41.16 ?  332 TRP   A CG  1 
ATOM   2441 C CD1 . TRP   A 1 332 ? 165.429 176.196 176.663 1.00 41.16 ?  332 TRP   A CD1 1 
ATOM   2442 C CD2 . TRP   A 1 332 ? 164.681 177.573 175.071 1.00 41.16 ?  332 TRP   A CD2 1 
ATOM   2443 N NE1 . TRP   A 1 332 ? 164.650 177.150 177.268 1.00 41.16 ?  332 TRP   A NE1 1 
ATOM   2444 C CE2 . TRP   A 1 332 ? 164.179 178.008 176.311 1.00 41.16 ?  332 TRP   A CE2 1 
ATOM   2445 C CE3 . TRP   A 1 332 ? 164.344 178.288 173.920 1.00 41.16 ?  332 TRP   A CE3 1 
ATOM   2446 C CZ2 . TRP   A 1 332 ? 163.357 179.122 176.433 1.00 41.16 ?  332 TRP   A CZ2 1 
ATOM   2447 C CZ3 . TRP   A 1 332 ? 163.529 179.393 174.043 1.00 41.16 ?  332 TRP   A CZ3 1 
ATOM   2448 C CH2 . TRP   A 1 332 ? 163.044 179.799 175.289 1.00 41.16 ?  332 TRP   A CH2 1 
ATOM   2449 N N   . LEU   A 1 333 ? 164.128 175.628 171.982 1.00 41.58 ?  333 LEU   A N   1 
ATOM   2450 C CA  . LEU   A 1 333 ? 162.919 176.217 171.415 1.00 41.58 ?  333 LEU   A CA  1 
ATOM   2451 C C   . LEU   A 1 333 ? 161.875 175.152 171.108 1.00 41.58 ?  333 LEU   A C   1 
ATOM   2452 O O   . LEU   A 1 333 ? 160.686 175.338 171.392 1.00 41.58 ?  333 LEU   A O   1 
ATOM   2453 C CB  . LEU   A 1 333 ? 163.259 176.999 170.147 1.00 41.58 ?  333 LEU   A CB  1 
ATOM   2454 C CG  . LEU   A 1 333 ? 163.844 178.397 170.337 1.00 41.58 ?  333 LEU   A CG  1 
ATOM   2455 C CD1 . LEU   A 1 333 ? 164.490 178.872 169.054 1.00 41.58 ?  333 LEU   A CD1 1 
ATOM   2456 C CD2 . LEU   A 1 333 ? 162.767 179.368 170.777 1.00 41.58 ?  333 LEU   A CD2 1 
ATOM   2457 N N   . LEU   A 1 334 ? 162.296 174.033 170.525 1.00 41.12 ?  334 LEU   A N   1 
ATOM   2458 C CA  . LEU   A 1 334 ? 161.361 173.004 170.096 1.00 41.12 ?  334 LEU   A CA  1 
ATOM   2459 C C   . LEU   A 1 334 ? 161.050 171.981 171.180 1.00 41.12 ?  334 LEU   A C   1 
ATOM   2460 O O   . LEU   A 1 334 ? 160.157 171.150 170.983 1.00 41.12 ?  334 LEU   A O   1 
ATOM   2461 C CB  . LEU   A 1 334 ? 161.907 172.284 168.859 1.00 41.12 ?  334 LEU   A CB  1 
ATOM   2462 C CG  . LEU   A 1 334 ? 161.755 173.045 167.539 1.00 41.12 ?  334 LEU   A CG  1 
ATOM   2463 C CD1 . LEU   A 1 334 ? 162.562 172.376 166.445 1.00 41.12 ?  334 LEU   A CD1 1 
ATOM   2464 C CD2 . LEU   A 1 334 ? 160.293 173.148 167.133 1.00 41.12 ?  334 LEU   A CD2 1 
ATOM   2465 N N   . HIS   A 1 335 ? 161.756 172.015 172.311 1.00 41.65 ?  335 HIS   A N   1 
ATOM   2466 C CA  . HIS   A 1 335 ? 161.489 171.087 173.401 1.00 41.65 ?  335 HIS   A CA  1 
ATOM   2467 C C   . HIS   A 1 335 ? 161.480 171.732 174.775 1.00 41.65 ?  335 HIS   A C   1 
ATOM   2468 O O   . HIS   A 1 335 ? 160.969 171.114 175.712 1.00 41.65 ?  335 HIS   A O   1 
ATOM   2469 C CB  . HIS   A 1 335 ? 162.530 169.961 173.402 1.00 41.65 ?  335 HIS   A CB  1 
ATOM   2470 C CG  . HIS   A 1 335 ? 162.412 169.028 172.242 1.00 41.65 ?  335 HIS   A CG  1 
ATOM   2471 N ND1 . HIS   A 1 335 ? 161.502 167.994 172.209 1.00 41.65 ?  335 HIS   A ND1 1 
ATOM   2472 C CD2 . HIS   A 1 335 ? 163.089 168.971 171.072 1.00 41.65 ?  335 HIS   A CD2 1 
ATOM   2473 C CE1 . HIS   A 1 335 ? 161.625 167.338 171.070 1.00 41.65 ?  335 HIS   A CE1 1 
ATOM   2474 N NE2 . HIS   A 1 335 ? 162.581 167.911 170.361 1.00 41.65 ?  335 HIS   A NE2 1 
ATOM   2475 N N   . GLY   A 1 336 ? 162.011 172.937 174.936 1.00 41.75 ?  336 GLY   A N   1 
ATOM   2476 C CA  . GLY   A 1 336 ? 162.108 173.549 176.236 1.00 41.75 ?  336 GLY   A CA  1 
ATOM   2477 C C   . GLY   A 1 336 ? 160.750 173.908 176.793 1.00 41.75 ?  336 GLY   A C   1 
ATOM   2478 O O   . GLY   A 1 336 ? 159.710 173.503 176.266 1.00 41.75 ?  336 GLY   A O   1 
ATOM   2479 N N   . PRO   A 1 337 ? 160.732 174.681 177.880 1.00 42.63 ?  337 PRO   A N   1 
ATOM   2480 C CA  . PRO   A 1 337 ? 159.443 175.105 178.443 1.00 42.63 ?  337 PRO   A CA  1 
ATOM   2481 C C   . PRO   A 1 337 ? 158.585 175.854 177.447 1.00 42.63 ?  337 PRO   A C   1 
ATOM   2482 O O   . PRO   A 1 337 ? 157.352 175.787 177.525 1.00 42.63 ?  337 PRO   A O   1 
ATOM   2483 C CB  . PRO   A 1 337 ? 159.851 175.995 179.624 1.00 42.63 ?  337 PRO   A CB  1 
ATOM   2484 C CG  . PRO   A 1 337 ? 161.241 175.582 179.959 1.00 42.63 ?  337 PRO   A CG  1 
ATOM   2485 C CD  . PRO   A 1 337 ? 161.872 175.172 178.669 1.00 42.63 ?  337 PRO   A CD  1 
ATOM   2486 N N   . TRP   A 1 338 ? 159.201 176.566 176.511 1.00 43.93 ?  338 TRP   A N   1 
ATOM   2487 C CA  . TRP   A 1 338 ? 158.468 177.328 175.503 1.00 43.93 ?  338 TRP   A CA  1 
ATOM   2488 C C   . TRP   A 1 338 ? 158.316 176.510 174.222 1.00 43.93 ?  338 TRP   A C   1 
ATOM   2489 O O   . TRP   A 1 338 ? 158.756 176.905 173.146 1.00 43.93 ?  338 TRP   A O   1 
ATOM   2490 C CB  . TRP   A 1 338 ? 159.175 178.649 175.223 1.00 43.93 ?  338 TRP   A CB  1 
ATOM   2491 C CG  . TRP   A 1 338 ? 159.306 179.546 176.410 1.00 43.93 ?  338 TRP   A CG  1 
ATOM   2492 C CD1 . TRP   A 1 338 ? 159.022 179.244 177.709 1.00 43.93 ?  338 TRP   A CD1 1 
ATOM   2493 C CD2 . TRP   A 1 338 ? 159.757 180.902 176.403 1.00 43.93 ?  338 TRP   A CD2 1 
ATOM   2494 N NE1 . TRP   A 1 338 ? 159.271 180.328 178.512 1.00 43.93 ?  338 TRP   A NE1 1 
ATOM   2495 C CE2 . TRP   A 1 338 ? 159.722 181.360 177.732 1.00 43.93 ?  338 TRP   A CE2 1 
ATOM   2496 C CE3 . TRP   A 1 338 ? 160.186 181.774 175.400 1.00 43.93 ?  338 TRP   A CE3 1 
ATOM   2497 C CZ2 . TRP   A 1 338 ? 160.101 182.650 178.084 1.00 43.93 ?  338 TRP   A CZ2 1 
ATOM   2498 C CZ3 . TRP   A 1 338 ? 160.561 183.051 175.751 1.00 43.93 ?  338 TRP   A CZ3 1 
ATOM   2499 C CH2 . TRP   A 1 338 ? 160.517 183.478 177.081 1.00 43.93 ?  338 TRP   A CH2 1 
ATOM   2500 N N   . ARG   A 1 339 ? 157.686 175.346 174.350 1.00 42.15 ?  339 ARG   A N   1 
ATOM   2501 C CA  . ARG   A 1 339 ? 157.348 174.526 173.197 1.00 42.15 ?  339 ARG   A CA  1 
ATOM   2502 C C   . ARG   A 1 339 ? 155.900 174.709 172.770 1.00 42.15 ?  339 ARG   A C   1 
ATOM   2503 O O   . ARG   A 1 339 ? 155.404 173.937 171.944 1.00 42.15 ?  339 ARG   A O   1 
ATOM   2504 C CB  . ARG   A 1 339 ? 157.631 173.050 173.482 1.00 42.15 ?  339 ARG   A CB  1 
ATOM   2505 C CG  . ARG   A 1 339 ? 157.014 172.503 174.758 1.00 42.15 ?  339 ARG   A CG  1 
ATOM   2506 C CD  . ARG   A 1 339 ? 157.289 171.013 174.875 1.00 42.15 ?  339 ARG   A CD  1 
ATOM   2507 N NE  . ARG   A 1 339 ? 157.057 170.497 176.218 1.00 42.15 ?  339 ARG   A NE  1 
ATOM   2508 C CZ  . ARG   A 1 339 ? 157.270 169.239 176.581 1.00 42.15 ?  339 ARG   A CZ  1 
ATOM   2509 N NH1 . ARG   A 1 339 ? 157.725 168.338 175.725 1.00 42.15 1  339 ARG   A NH1 1 
ATOM   2510 N NH2 . ARG   A 1 339 ? 157.022 168.875 177.836 1.00 42.15 ?  339 ARG   A NH2 1 
ATOM   2511 N N   . ASP   A 1 340 ? 155.213 175.713 173.316 1.00 43.68 ?  340 ASP   A N   1 
ATOM   2512 C CA  . ASP   A 1 340 ? 153.832 176.000 172.957 1.00 43.68 ?  340 ASP   A CA  1 
ATOM   2513 C C   . ASP   A 1 340 ? 153.603 177.428 172.493 1.00 43.68 ?  340 ASP   A C   1 
ATOM   2514 O O   . ASP   A 1 340 ? 152.637 177.663 171.757 1.00 43.68 ?  340 ASP   A O   1 
ATOM   2515 C CB  . ASP   A 1 340 ? 152.904 175.722 174.147 1.00 43.68 ?  340 ASP   A CB  1 
ATOM   2516 C CG  . ASP   A 1 340 ? 152.802 174.249 174.471 1.00 43.68 ?  340 ASP   A CG  1 
ATOM   2517 O OD1 . ASP   A 1 340 ? 152.947 173.424 173.545 1.00 43.68 ?  340 ASP   A OD1 1 
ATOM   2518 O OD2 . ASP   A 1 340 ? 152.579 173.914 175.653 1.00 43.68 -1 340 ASP   A OD2 1 
ATOM   2519 N N   . LYS   A 1 341 ? 154.443 178.383 172.886 1.00 44.21 ?  341 LYS   A N   1 
ATOM   2520 C CA  . LYS   A 1 341 ? 154.258 179.760 172.450 1.00 44.21 ?  341 LYS   A CA  1 
ATOM   2521 C C   . LYS   A 1 341 ? 154.337 179.836 170.933 1.00 44.21 ?  341 LYS   A C   1 
ATOM   2522 O O   . LYS   A 1 341 ? 155.173 179.180 170.306 1.00 44.21 ?  341 LYS   A O   1 
ATOM   2523 C CB  . LYS   A 1 341 ? 155.316 180.679 173.072 1.00 44.21 ?  341 LYS   A CB  1 
ATOM   2524 C CG  . LYS   A 1 341 ? 155.620 180.433 174.549 1.00 44.21 ?  341 LYS   A CG  1 
ATOM   2525 C CD  . LYS   A 1 341 ? 154.449 180.787 175.452 1.00 44.21 ?  341 LYS   A CD  1 
ATOM   2526 C CE  . LYS   A 1 341 ? 154.137 182.277 175.440 1.00 44.21 ?  341 LYS   A CE  1 
ATOM   2527 N NZ  . LYS   A 1 341 ? 152.932 182.596 176.254 1.00 44.21 1  341 LYS   A NZ  1 
ATOM   2528 N N   . VAL   A 1 342 ? 153.459 180.644 170.338 1.00 43.88 ?  342 VAL   A N   1 
ATOM   2529 C CA  . VAL   A 1 342 ? 153.461 180.785 168.884 1.00 43.88 ?  342 VAL   A CA  1 
ATOM   2530 C C   . VAL   A 1 342 ? 154.819 181.285 168.415 1.00 43.88 ?  342 VAL   A C   1 
ATOM   2531 O O   . VAL   A 1 342 ? 155.411 180.751 167.467 1.00 43.88 ?  342 VAL   A O   1 
ATOM   2532 C CB  . VAL   A 1 342 ? 152.330 181.726 168.434 1.00 43.88 ?  342 VAL   A CB  1 
ATOM   2533 C CG1 . VAL   A 1 342 ? 152.258 181.779 166.916 1.00 43.88 ?  342 VAL   A CG1 1 
ATOM   2534 C CG2 . VAL   A 1 342 ? 150.997 181.281 169.021 1.00 43.88 ?  342 VAL   A CG2 1 
ATOM   2535 N N   . GLY   A 1 343 ? 155.342 182.307 169.088 1.00 43.63 ?  343 GLY   A N   1 
ATOM   2536 C CA  . GLY   A 1 343 ? 156.648 182.822 168.730 1.00 43.63 ?  343 GLY   A CA  1 
ATOM   2537 C C   . GLY   A 1 343 ? 157.748 181.793 168.876 1.00 43.63 ?  343 GLY   A C   1 
ATOM   2538 O O   . GLY   A 1 343 ? 158.700 181.785 168.097 1.00 43.63 ?  343 GLY   A O   1 
ATOM   2539 N N   . ALA   A 1 344 ? 157.646 180.920 169.877 1.00 43.23 ?  344 ALA   A N   1 
ATOM   2540 C CA  . ALA   A 1 344 ? 158.684 179.915 170.071 1.00 43.23 ?  344 ALA   A CA  1 
ATOM   2541 C C   . ALA   A 1 344 ? 158.788 179.001 168.858 1.00 43.23 ?  344 ALA   A C   1 
ATOM   2542 O O   . ALA   A 1 344 ? 159.879 178.785 168.323 1.00 43.23 ?  344 ALA   A O   1 
ATOM   2543 C CB  . ALA   A 1 344 ? 158.401 179.106 171.334 1.00 43.23 ?  344 ALA   A CB  1 
ATOM   2544 N N   . LYS   A 1 345 ? 157.655 178.461 168.403 1.00 42.62 ?  345 LYS   A N   1 
ATOM   2545 C CA  . LYS   A 1 345 ? 157.672 177.615 167.212 1.00 42.62 ?  345 LYS   A CA  1 
ATOM   2546 C C   . LYS   A 1 345 ? 158.103 178.409 165.987 1.00 42.62 ?  345 LYS   A C   1 
ATOM   2547 O O   . LYS   A 1 345 ? 158.874 177.914 165.154 1.00 42.62 ?  345 LYS   A O   1 
ATOM   2548 C CB  . LYS   A 1 345 ? 156.295 176.989 166.974 1.00 42.62 ?  345 LYS   A CB  1 
ATOM   2549 C CG  . LYS   A 1 345 ? 155.523 176.607 168.232 1.00 42.62 ?  345 LYS   A CG  1 
ATOM   2550 C CD  . LYS   A 1 345 ? 154.195 175.940 167.898 1.00 42.62 ?  345 LYS   A CD  1 
ATOM   2551 C CE  . LYS   A 1 345 ? 154.381 174.539 167.331 1.00 42.62 ?  345 LYS   A CE  1 
ATOM   2552 N NZ  . LYS   A 1 345 ? 155.020 173.614 168.307 1.00 42.62 1  345 LYS   A NZ  1 
ATOM   2553 N N   . VAL   A 1 346 ? 157.614 179.646 165.860 1.00 42.73 ?  346 VAL   A N   1 
ATOM   2554 C CA  . VAL   A 1 346 ? 157.957 180.465 164.701 1.00 42.73 ?  346 VAL   A CA  1 
ATOM   2555 C C   . VAL   A 1 346 ? 159.465 180.660 164.619 1.00 42.73 ?  346 VAL   A C   1 
ATOM   2556 O O   . VAL   A 1 346 ? 160.079 180.463 163.566 1.00 42.73 ?  346 VAL   A O   1 
ATOM   2557 C CB  . VAL   A 1 346 ? 157.219 181.814 164.763 1.00 42.73 ?  346 VAL   A CB  1 
ATOM   2558 C CG1 . VAL   A 1 346 ? 157.837 182.806 163.792 1.00 42.73 ?  346 VAL   A CG1 1 
ATOM   2559 C CG2 . VAL   A 1 346 ? 155.745 181.621 164.457 1.00 42.73 ?  346 VAL   A CG2 1 
ATOM   2560 N N   . PHE   A 1 347 ? 160.089 181.030 165.735 1.00 42.03 ?  347 PHE   A N   1 
ATOM   2561 C CA  . PHE   A 1 347 ? 161.514 181.325 165.710 1.00 42.03 ?  347 PHE   A CA  1 
ATOM   2562 C C   . PHE   A 1 347 ? 162.351 180.056 165.661 1.00 42.03 ?  347 PHE   A C   1 
ATOM   2563 O O   . PHE   A 1 347 ? 163.445 180.066 165.090 1.00 42.03 ?  347 PHE   A O   1 
ATOM   2564 C CB  . PHE   A 1 347 ? 161.886 182.187 166.911 1.00 42.03 ?  347 PHE   A CB  1 
ATOM   2565 C CG  . PHE   A 1 347 ? 161.737 183.653 166.650 1.00 42.03 ?  347 PHE   A CG  1 
ATOM   2566 C CD1 . PHE   A 1 347 ? 160.502 184.184 166.331 1.00 42.03 ?  347 PHE   A CD1 1 
ATOM   2567 C CD2 . PHE   A 1 347 ? 162.830 184.494 166.684 1.00 42.03 ?  347 PHE   A CD2 1 
ATOM   2568 C CE1 . PHE   A 1 347 ? 160.355 185.527 166.074 1.00 42.03 ?  347 PHE   A CE1 1 
ATOM   2569 C CE2 . PHE   A 1 347 ? 162.689 185.839 166.426 1.00 42.03 ?  347 PHE   A CE2 1 
ATOM   2570 C CZ  . PHE   A 1 347 ? 161.449 186.356 166.120 1.00 42.03 ?  347 PHE   A CZ  1 
ATOM   2571 N N   . GLY   A 1 348 ? 161.856 178.950 166.216 1.00 41.54 ?  348 GLY   A N   1 
ATOM   2572 C CA  . GLY   A 1 348 ? 162.551 177.688 166.038 1.00 41.54 ?  348 GLY   A CA  1 
ATOM   2573 C C   . GLY   A 1 348 ? 162.603 177.269 164.584 1.00 41.54 ?  348 GLY   A C   1 
ATOM   2574 O O   . GLY   A 1 348 ? 163.665 176.903 164.071 1.00 41.54 ?  348 GLY   A O   1 
ATOM   2575 N N   . CYS   A 1 349 ? 161.466 177.340 163.888 1.00 42.76 ?  349 CYS   A N   1 
ATOM   2576 C CA  . CYS   A 1 349 ? 161.466 176.986 162.474 1.00 42.76 ?  349 CYS   A CA  1 
ATOM   2577 C C   . CYS   A 1 349 ? 162.266 177.997 161.664 1.00 42.76 ?  349 CYS   A C   1 
ATOM   2578 O O   . CYS   A 1 349 ? 162.912 177.637 160.675 1.00 42.76 ?  349 CYS   A O   1 
ATOM   2579 C CB  . CYS   A 1 349 ? 160.034 176.876 161.946 1.00 42.76 ?  349 CYS   A CB  1 
ATOM   2580 S SG  . CYS   A 1 349 ? 159.114 178.426 161.851 1.00 42.76 ?  349 CYS   A SG  1 
ATOM   2581 N N   . GLY   A 1 350 ? 162.248 179.266 162.075 1.00 41.68 ?  350 GLY   A N   1 
ATOM   2582 C CA  . GLY   A 1 350 ? 163.068 180.256 161.398 1.00 41.68 ?  350 GLY   A CA  1 
ATOM   2583 C C   . GLY   A 1 350 ? 164.548 179.950 161.511 1.00 41.68 ?  350 GLY   A C   1 
ATOM   2584 O O   . GLY   A 1 350 ? 165.286 180.010 160.526 1.00 41.68 ?  350 GLY   A O   1 
ATOM   2585 N N   . TRP   A 1 351 ? 165.004 179.616 162.720 1.00 41.43 ?  351 TRP   A N   1 
ATOM   2586 C CA  . TRP   A 1 351 ? 166.406 179.262 162.904 1.00 41.43 ?  351 TRP   A CA  1 
ATOM   2587 C C   . TRP   A 1 351 ? 166.757 178.007 162.120 1.00 41.43 ?  351 TRP   A C   1 
ATOM   2588 O O   . TRP   A 1 351 ? 167.826 177.932 161.504 1.00 41.43 ?  351 TRP   A O   1 
ATOM   2589 C CB  . TRP   A 1 351 ? 166.710 179.073 164.388 1.00 41.43 ?  351 TRP   A CB  1 
ATOM   2590 C CG  . TRP   A 1 351 ? 166.923 180.363 165.101 1.00 41.43 ?  351 TRP   A CG  1 
ATOM   2591 C CD1 . TRP   A 1 351 ? 166.174 180.869 166.120 1.00 41.43 ?  351 TRP   A CD1 1 
ATOM   2592 C CD2 . TRP   A 1 351 ? 167.956 181.320 164.848 1.00 41.43 ?  351 TRP   A CD2 1 
ATOM   2593 N NE1 . TRP   A 1 351 ? 166.675 182.083 166.517 1.00 41.43 ?  351 TRP   A NE1 1 
ATOM   2594 C CE2 . TRP   A 1 351 ? 167.770 182.382 165.751 1.00 41.43 ?  351 TRP   A CE2 1 
ATOM   2595 C CE3 . TRP   A 1 351 ? 169.020 181.382 163.945 1.00 41.43 ?  351 TRP   A CE3 1 
ATOM   2596 C CZ2 . TRP   A 1 351 ? 168.607 183.493 165.778 1.00 41.43 ?  351 TRP   A CZ2 1 
ATOM   2597 C CZ3 . TRP   A 1 351 ? 169.850 182.484 163.973 1.00 41.43 ?  351 TRP   A CZ3 1 
ATOM   2598 C CH2 . TRP   A 1 351 ? 169.639 183.525 164.883 1.00 41.43 ?  351 TRP   A CH2 1 
ATOM   2599 N N   . LEU   A 1 352 ? 165.872 177.008 162.128 1.00 41.91 ?  352 LEU   A N   1 
ATOM   2600 C CA  . LEU   A 1 352 ? 166.140 175.813 161.340 1.00 41.91 ?  352 LEU   A CA  1 
ATOM   2601 C C   . LEU   A 1 352 ? 166.281 176.140 159.863 1.00 41.91 ?  352 LEU   A C   1 
ATOM   2602 O O   . LEU   A 1 352 ? 167.258 175.725 159.235 1.00 41.91 ?  352 LEU   A O   1 
ATOM   2603 C CB  . LEU   A 1 352 ? 165.037 174.773 161.540 1.00 41.91 ?  352 LEU   A CB  1 
ATOM   2604 C CG  . LEU   A 1 352 ? 164.951 174.094 162.906 1.00 41.91 ?  352 LEU   A CG  1 
ATOM   2605 C CD1 . LEU   A 1 352 ? 163.704 173.233 162.980 1.00 41.91 ?  352 LEU   A CD1 1 
ATOM   2606 C CD2 . LEU   A 1 352 ? 166.182 173.246 163.169 1.00 41.91 ?  352 LEU   A CD2 1 
ATOM   2607 N N   . VAL   A 1 353 ? 165.333 176.882 159.288 1.00 41.30 ?  353 VAL   A N   1 
ATOM   2608 C CA  . VAL   A 1 353 ? 165.416 177.174 157.861 1.00 41.30 ?  353 VAL   A CA  1 
ATOM   2609 C C   . VAL   A 1 353 ? 166.619 178.046 157.539 1.00 41.30 ?  353 VAL   A C   1 
ATOM   2610 O O   . VAL   A 1 353 ? 167.236 177.870 156.481 1.00 41.30 ?  353 VAL   A O   1 
ATOM   2611 C CB  . VAL   A 1 353 ? 164.132 177.841 157.338 1.00 41.30 ?  353 VAL   A CB  1 
ATOM   2612 C CG1 . VAL   A 1 353 ? 162.937 176.923 157.538 1.00 41.30 ?  353 VAL   A CG1 1 
ATOM   2613 C CG2 . VAL   A 1 353 ? 163.898 179.178 158.012 1.00 41.30 ?  353 VAL   A CG2 1 
ATOM   2614 N N   . LEU   A 1 354 ? 166.979 178.977 158.423 1.00 40.70 ?  354 LEU   A N   1 
ATOM   2615 C CA  . LEU   A 1 354 ? 168.130 179.832 158.172 1.00 40.70 ?  354 LEU   A CA  1 
ATOM   2616 C C   . LEU   A 1 354 ? 169.432 179.043 158.210 1.00 40.70 ?  354 LEU   A C   1 
ATOM   2617 O O   . LEU   A 1 354 ? 170.253 179.153 157.293 1.00 40.70 ?  354 LEU   A O   1 
ATOM   2618 C CB  . LEU   A 1 354 ? 168.160 180.962 159.199 1.00 40.70 ?  354 LEU   A CB  1 
ATOM   2619 C CG  . LEU   A 1 354 ? 169.269 181.999 159.051 1.00 40.70 ?  354 LEU   A CG  1 
ATOM   2620 C CD1 . LEU   A 1 354 ? 169.131 182.736 157.734 1.00 40.70 ?  354 LEU   A CD1 1 
ATOM   2621 C CD2 . LEU   A 1 354 ? 169.230 182.968 160.219 1.00 40.70 ?  354 LEU   A CD2 1 
ATOM   2622 N N   . LEU   A 1 355 ? 169.638 178.235 159.253 1.00 41.06 ?  355 LEU   A N   1 
ATOM   2623 C CA  . LEU   A 1 355 ? 170.898 177.515 159.391 1.00 41.06 ?  355 LEU   A CA  1 
ATOM   2624 C C   . LEU   A 1 355 ? 171.013 176.379 158.384 1.00 41.06 ?  355 LEU   A C   1 
ATOM   2625 O O   . LEU   A 1 355 ? 172.068 176.207 157.766 1.00 41.06 ?  355 LEU   A O   1 
ATOM   2626 C CB  . LEU   A 1 355 ? 171.042 176.973 160.814 1.00 41.06 ?  355 LEU   A CB  1 
ATOM   2627 C CG  . LEU   A 1 355 ? 171.106 177.992 161.954 1.00 41.06 ?  355 LEU   A CG  1 
ATOM   2628 C CD1 . LEU   A 1 355 ? 171.643 177.330 163.209 1.00 41.06 ?  355 LEU   A CD1 1 
ATOM   2629 C CD2 . LEU   A 1 355 ? 171.954 179.195 161.588 1.00 41.06 ?  355 LEU   A CD2 1 
ATOM   2630 N N   . LEU   A 1 356 ? 169.950 175.591 158.202 1.00 41.64 ?  356 LEU   A N   1 
ATOM   2631 C CA  . LEU   A 1 356 ? 170.020 174.471 157.274 1.00 41.64 ?  356 LEU   A CA  1 
ATOM   2632 C C   . LEU   A 1 356 ? 170.360 174.947 155.871 1.00 41.64 ?  356 LEU   A C   1 
ATOM   2633 O O   . LEU   A 1 356 ? 171.207 174.354 155.193 1.00 41.64 ?  356 LEU   A O   1 
ATOM   2634 C CB  . LEU   A 1 356 ? 168.692 173.716 157.274 1.00 41.64 ?  356 LEU   A CB  1 
ATOM   2635 C CG  . LEU   A 1 356 ? 168.522 172.685 158.389 1.00 41.64 ?  356 LEU   A CG  1 
ATOM   2636 C CD1 . LEU   A 1 356 ? 167.053 172.392 158.623 1.00 41.64 ?  356 LEU   A CD1 1 
ATOM   2637 C CD2 . LEU   A 1 356 ? 169.274 171.411 158.045 1.00 41.64 ?  356 LEU   A CD2 1 
ATOM   2638 N N   . ILE   A 1 357 ? 169.714 176.020 155.419 1.00 41.44 ?  357 ILE   A N   1 
ATOM   2639 C CA  . ILE   A 1 357 ? 170.058 176.609 154.129 1.00 41.44 ?  357 ILE   A CA  1 
ATOM   2640 C C   . ILE   A 1 357 ? 171.391 177.336 154.221 1.00 41.44 ?  357 ILE   A C   1 
ATOM   2641 O O   . ILE   A 1 357 ? 172.357 177.000 153.527 1.00 41.44 ?  357 ILE   A O   1 
ATOM   2642 C CB  . ILE   A 1 357 ? 168.940 177.554 153.657 1.00 41.44 ?  357 ILE   A CB  1 
ATOM   2643 C CG1 . ILE   A 1 357 ? 167.672 176.761 153.333 1.00 41.44 ?  357 ILE   A CG1 1 
ATOM   2644 C CG2 . ILE   A 1 357 ? 169.400 178.359 152.451 1.00 41.44 ?  357 ILE   A CG2 1 
ATOM   2645 C CD1 . ILE   A 1 357 ? 166.414 177.604 153.314 1.00 41.44 ?  357 ILE   A CD1 1 
ATOM   2646 N N   . GLY   A 1 358 ? 171.456 178.348 155.074 1.00 40.88 ?  358 GLY   A N   1 
ATOM   2647 C CA  . GLY   A 1 358 ? 172.682 179.086 155.277 1.00 40.88 ?  358 GLY   A CA  1 
ATOM   2648 C C   . GLY   A 1 358 ? 172.737 180.277 154.351 1.00 40.88 ?  358 GLY   A C   1 
ATOM   2649 O O   . GLY   A 1 358 ? 173.050 180.134 153.166 1.00 40.88 ?  358 GLY   A O   1 
ATOM   2650 N N   . VAL   A 1 359 ? 172.430 181.458 154.873 1.00 40.62 ?  359 VAL   A N   1 
ATOM   2651 C CA  . VAL   A 1 359 ? 172.465 182.677 154.073 1.00 40.62 ?  359 VAL   A CA  1 
ATOM   2652 C C   . VAL   A 1 359 ? 173.903 183.167 153.953 1.00 40.62 ?  359 VAL   A C   1 
ATOM   2653 O O   . VAL   A 1 359 ? 174.334 183.507 152.844 1.00 40.62 ?  359 VAL   A O   1 
ATOM   2654 C CB  . VAL   A 1 359 ? 171.552 183.761 154.665 1.00 40.62 ?  359 VAL   A CB  1 
ATOM   2655 C CG1 . VAL   A 1 359 ? 171.698 185.053 153.883 1.00 40.62 ?  359 VAL   A CG1 1 
ATOM   2656 C CG2 . VAL   A 1 359 ? 170.108 183.294 154.642 1.00 40.62 ?  359 VAL   A CG2 1 
ATOM   2657 N N   . PRO   A 1 360 ? 174.675 183.251 155.042 1.00 39.26 ?  360 PRO   A N   1 
ATOM   2658 C CA  . PRO   A 1 360 ? 176.067 183.711 154.887 1.00 39.26 ?  360 PRO   A CA  1 
ATOM   2659 C C   . PRO   A 1 360 ? 176.890 182.849 153.950 1.00 39.26 ?  360 PRO   A C   1 
ATOM   2660 O O   . PRO   A 1 360 ? 177.695 183.380 153.174 1.00 39.26 ?  360 PRO   A O   1 
ATOM   2661 C CB  . PRO   A 1 360 ? 176.615 183.674 156.321 1.00 39.26 ?  360 PRO   A CB  1 
ATOM   2662 C CG  . PRO   A 1 360 ? 175.617 182.936 157.123 1.00 39.26 ?  360 PRO   A CG  1 
ATOM   2663 C CD  . PRO   A 1 360 ? 174.306 183.126 156.460 1.00 39.26 ?  360 PRO   A CD  1 
ATOM   2664 N N   . TRP   A 1 361 ? 176.709 181.529 153.992 1.00 39.86 ?  361 TRP   A N   1 
ATOM   2665 C CA  . TRP   A 1 361 ? 177.453 180.668 153.081 1.00 39.86 ?  361 TRP   A CA  1 
ATOM   2666 C C   . TRP   A 1 361 ? 177.103 180.979 151.634 1.00 39.86 ?  361 TRP   A C   1 
ATOM   2667 O O   . TRP   A 1 361 ? 177.983 181.013 150.766 1.00 39.86 ?  361 TRP   A O   1 
ATOM   2668 C CB  . TRP   A 1 361 ? 177.174 179.199 153.393 1.00 39.86 ?  361 TRP   A CB  1 
ATOM   2669 C CG  . TRP   A 1 361 ? 177.657 178.287 152.320 1.00 39.86 ?  361 TRP   A CG  1 
ATOM   2670 C CD1 . TRP   A 1 361 ? 178.951 177.992 152.022 1.00 39.86 ?  361 TRP   A CD1 1 
ATOM   2671 C CD2 . TRP   A 1 361 ? 176.854 177.557 151.388 1.00 39.86 ?  361 TRP   A CD2 1 
ATOM   2672 N NE1 . TRP   A 1 361 ? 179.006 177.119 150.964 1.00 39.86 ?  361 TRP   A NE1 1 
ATOM   2673 C CE2 . TRP   A 1 361 ? 177.730 176.837 150.556 1.00 39.86 ?  361 TRP   A CE2 1 
ATOM   2674 C CE3 . TRP   A 1 361 ? 175.478 177.441 151.177 1.00 39.86 ?  361 TRP   A CE3 1 
ATOM   2675 C CZ2 . TRP   A 1 361 ? 177.278 176.014 149.533 1.00 39.86 ?  361 TRP   A CZ2 1 
ATOM   2676 C CZ3 . TRP   A 1 361 ? 175.031 176.623 150.159 1.00 39.86 ?  361 TRP   A CZ3 1 
ATOM   2677 C CH2 . TRP   A 1 361 ? 175.928 175.920 149.350 1.00 39.86 ?  361 TRP   A CH2 1 
ATOM   2678 N N   . LEU   A 1 362 ? 175.818 181.206 151.353 1.00 39.67 ?  362 LEU   A N   1 
ATOM   2679 C CA  . LEU   A 1 362 ? 175.407 181.540 149.995 1.00 39.67 ?  362 LEU   A CA  1 
ATOM   2680 C C   . LEU   A 1 362 ? 175.944 182.900 149.574 1.00 39.67 ?  362 LEU   A C   1 
ATOM   2681 O O   . LEU   A 1 362 ? 176.362 183.081 148.425 1.00 39.67 ?  362 LEU   A O   1 
ATOM   2682 C CB  . LEU   A 1 362 ? 173.885 181.515 149.893 1.00 39.67 ?  362 LEU   A CB  1 
ATOM   2683 C CG  . LEU   A 1 362 ? 173.233 180.138 149.998 1.00 39.67 ?  362 LEU   A CG  1 
ATOM   2684 C CD1 . LEU   A 1 362 ? 171.723 180.279 150.094 1.00 39.67 ?  362 LEU   A CD1 1 
ATOM   2685 C CD2 . LEU   A 1 362 ? 173.616 179.267 148.814 1.00 39.67 ?  362 LEU   A CD2 1 
ATOM   2686 N N   . LEU   A 1 363 ? 175.938 183.871 150.487 1.00 38.53 ?  363 LEU   A N   1 
ATOM   2687 C CA  . LEU   A 1 363 ? 176.373 185.219 150.146 1.00 38.53 ?  363 LEU   A CA  1 
ATOM   2688 C C   . LEU   A 1 363 ? 177.881 185.317 149.981 1.00 38.53 ?  363 LEU   A C   1 
ATOM   2689 O O   . LEU   A 1 363 ? 178.354 186.205 149.265 1.00 38.53 ?  363 LEU   A O   1 
ATOM   2690 C CB  . LEU   A 1 363 ? 175.917 186.209 151.216 1.00 38.53 ?  363 LEU   A CB  1 
ATOM   2691 C CG  . LEU   A 1 363 ? 174.414 186.461 151.319 1.00 38.53 ?  363 LEU   A CG  1 
ATOM   2692 C CD1 . LEU   A 1 363 ? 174.103 187.214 152.597 1.00 38.53 ?  363 LEU   A CD1 1 
ATOM   2693 C CD2 . LEU   A 1 363 ? 173.915 187.228 150.108 1.00 38.53 ?  363 LEU   A CD2 1 
ATOM   2694 N N   . SER   A 1 364 ? 178.645 184.429 150.618 1.00 39.46 ?  364 SER   A N   1 
ATOM   2695 C CA  . SER   A 1 364 ? 180.098 184.530 150.537 1.00 39.46 ?  364 SER   A CA  1 
ATOM   2696 C C   . SER   A 1 364 ? 180.585 184.484 149.097 1.00 39.46 ?  364 SER   A C   1 
ATOM   2697 O O   . SER   A 1 364 ? 181.675 184.982 148.796 1.00 39.46 ?  364 SER   A O   1 
ATOM   2698 C CB  . SER   A 1 364 ? 180.748 183.410 151.344 1.00 39.46 ?  364 SER   A CB  1 
ATOM   2699 O OG  . SER   A 1 364 ? 180.752 182.195 150.614 1.00 39.46 ?  364 SER   A OG  1 
ATOM   2700 N N   . PHE   A 1 365 ? 179.804 183.886 148.196 1.00 40.24 ?  365 PHE   A N   1 
ATOM   2701 C CA  . PHE   A 1 365 ? 180.220 183.805 146.801 1.00 40.24 ?  365 PHE   A CA  1 
ATOM   2702 C C   . PHE   A 1 365 ? 180.231 185.171 146.129 1.00 40.24 ?  365 PHE   A C   1 
ATOM   2703 O O   . PHE   A 1 365 ? 181.094 185.437 145.286 1.00 40.24 ?  365 PHE   A O   1 
ATOM   2704 C CB  . PHE   A 1 365 ? 179.300 182.855 146.038 1.00 40.24 ?  365 PHE   A CB  1 
ATOM   2705 C CG  . PHE   A 1 365 ? 179.363 181.439 146.520 1.00 40.24 ?  365 PHE   A CG  1 
ATOM   2706 C CD1 . PHE   A 1 365 ? 178.574 181.016 147.573 1.00 40.24 ?  365 PHE   A CD1 1 
ATOM   2707 C CD2 . PHE   A 1 365 ? 180.209 180.529 145.917 1.00 40.24 ?  365 PHE   A CD2 1 
ATOM   2708 C CE1 . PHE   A 1 365 ? 178.630 179.714 148.018 1.00 40.24 ?  365 PHE   A CE1 1 
ATOM   2709 C CE2 . PHE   A 1 365 ? 180.269 179.224 146.357 1.00 40.24 ?  365 PHE   A CE2 1 
ATOM   2710 C CZ  . PHE   A 1 365 ? 179.477 178.817 147.409 1.00 40.24 ?  365 PHE   A CZ  1 
ATOM   2711 N N   . ALA   A 1 366 ? 179.291 186.046 146.482 1.00 40.06 ?  366 ALA   A N   1 
ATOM   2712 C CA  . ALA   A 1 366 ? 179.156 187.306 145.760 1.00 40.06 ?  366 ALA   A CA  1 
ATOM   2713 C C   . ALA   A 1 366 ? 180.390 188.183 145.920 1.00 40.06 ?  366 ALA   A C   1 
ATOM   2714 O O   . ALA   A 1 366 ? 180.861 188.780 144.945 1.00 40.06 ?  366 ALA   A O   1 
ATOM   2715 C CB  . ALA   A 1 366 ? 177.911 188.049 146.236 1.00 40.06 ?  366 ALA   A CB  1 
ATOM   2716 N N   . GLN   A 1 367 ? 180.929 188.277 147.132 1.00 41.10 ?  367 GLN   A N   1 
ATOM   2717 C CA  . GLN   A 1 367 ? 182.010 189.216 147.381 1.00 41.10 ?  367 GLN   A CA  1 
ATOM   2718 C C   . GLN   A 1 367 ? 183.248 188.834 146.570 1.00 41.10 ?  367 GLN   A C   1 
ATOM   2719 O O   . GLN   A 1 367 ? 183.519 187.649 146.361 1.00 41.10 ?  367 GLN   A O   1 
ATOM   2720 C CB  . GLN   A 1 367 ? 182.361 189.259 148.865 1.00 41.10 ?  367 GLN   A CB  1 
ATOM   2721 C CG  . GLN   A 1 367 ? 182.725 187.918 149.464 1.00 41.10 ?  367 GLN   A CG  1 
ATOM   2722 C CD  . GLN   A 1 367 ? 182.896 187.987 150.963 1.00 41.10 ?  367 GLN   A CD  1 
ATOM   2723 O OE1 . GLN   A 1 367 ? 182.888 189.068 151.548 1.00 41.10 ?  367 GLN   A OE1 1 
ATOM   2724 N NE2 . GLN   A 1 367 ? 183.053 186.832 151.595 1.00 41.10 ?  367 GLN   A NE2 1 
ATOM   2725 N N   . PRO   A 1 368 ? 184.019 189.821 146.100 1.00 43.77 ?  368 PRO   A N   1 
ATOM   2726 C CA  . PRO   A 1 368 ? 185.184 189.502 145.263 1.00 43.77 ?  368 PRO   A CA  1 
ATOM   2727 C C   . PRO   A 1 368 ? 186.150 188.553 145.950 1.00 43.77 ?  368 PRO   A C   1 
ATOM   2728 O O   . PRO   A 1 368 ? 186.485 187.494 145.410 1.00 43.77 ?  368 PRO   A O   1 
ATOM   2729 C CB  . PRO   A 1 368 ? 185.829 190.872 145.014 1.00 43.77 ?  368 PRO   A CB  1 
ATOM   2730 C CG  . PRO   A 1 368 ? 184.748 191.857 145.247 1.00 43.77 ?  368 PRO   A CG  1 
ATOM   2731 C CD  . PRO   A 1 368 ? 183.884 191.272 146.316 1.00 43.77 ?  368 PRO   A CD  1 
ATOM   2732 N N   . ASP   A 1 369 ? 186.603 188.925 147.144 1.00 46.10 ?  369 ASP   A N   1 
ATOM   2733 C CA  . ASP   A 1 369 ? 187.539 188.117 147.907 1.00 46.10 ?  369 ASP   A CA  1 
ATOM   2734 C C   . ASP   A 1 369 ? 187.292 188.343 149.391 1.00 46.10 ?  369 ASP   A C   1 
ATOM   2735 O O   . ASP   A 1 369 ? 186.704 189.346 149.803 1.00 46.10 ?  369 ASP   A O   1 
ATOM   2736 C CB  . ASP   A 1 369 ? 188.992 188.438 147.525 1.00 46.10 ?  369 ASP   A CB  1 
ATOM   2737 C CG  . ASP   A 1 369 ? 189.412 189.850 147.908 1.00 46.10 ?  369 ASP   A CG  1 
ATOM   2738 O OD1 . ASP   A 1 369 ? 188.888 190.407 148.895 1.00 46.10 ?  369 ASP   A OD1 1 
ATOM   2739 O OD2 . ASP   A 1 369 ? 190.282 190.410 147.208 1.00 46.10 -1 369 ASP   A OD2 1 
ATOM   2740 N N   . ILE   A 1 370 ? 187.763 187.394 150.203 1.00 46.27 ?  370 ILE   A N   1 
ATOM   2741 C CA  . ILE   A 1 370 ? 187.573 187.474 151.646 1.00 46.27 ?  370 ILE   A CA  1 
ATOM   2742 C C   . ILE   A 1 370 ? 188.177 188.731 152.252 1.00 46.27 ?  370 ILE   A C   1 
ATOM   2743 O O   . ILE   A 1 370 ? 187.864 189.064 153.401 1.00 46.27 ?  370 ILE   A O   1 
ATOM   2744 C CB  . ILE   A 1 370 ? 188.165 186.224 152.329 1.00 46.27 ?  370 ILE   A CB  1 
ATOM   2745 C CG1 . ILE   A 1 370 ? 189.643 186.060 151.969 1.00 46.27 ?  370 ILE   A CG1 1 
ATOM   2746 C CG2 . ILE   A 1 370 ? 187.383 184.986 151.928 1.00 46.27 ?  370 ILE   A CG2 1 
ATOM   2747 C CD1 . ILE   A 1 370 ? 190.337 184.958 152.739 1.00 46.27 ?  370 ILE   A CD1 1 
ATOM   2748 N N   . TRP   A 1 371 ? 189.029 189.440 151.515 1.00 47.02 ?  371 TRP   A N   1 
ATOM   2749 C CA  . TRP   A 1 371 ? 189.667 190.653 152.006 1.00 47.02 ?  371 TRP   A CA  1 
ATOM   2750 C C   . TRP   A 1 371 ? 188.996 191.925 151.504 1.00 47.02 ?  371 TRP   A C   1 
ATOM   2751 O O   . TRP   A 1 371 ? 189.532 193.016 151.720 1.00 47.02 ?  371 TRP   A O   1 
ATOM   2752 C CB  . TRP   A 1 371 ? 191.147 190.660 151.610 1.00 47.02 ?  371 TRP   A CB  1 
ATOM   2753 C CG  . TRP   A 1 371 ? 191.838 189.365 151.902 1.00 47.02 ?  371 TRP   A CG  1 
ATOM   2754 C CD1 . TRP   A 1 371 ? 192.187 188.401 151.003 1.00 47.02 ?  371 TRP   A CD1 1 
ATOM   2755 C CD2 . TRP   A 1 371 ? 192.260 188.888 153.185 1.00 47.02 ?  371 TRP   A CD2 1 
ATOM   2756 N NE1 . TRP   A 1 371 ? 192.802 187.355 151.645 1.00 47.02 ?  371 TRP   A NE1 1 
ATOM   2757 C CE2 . TRP   A 1 371 ? 192.859 187.629 152.986 1.00 47.02 ?  371 TRP   A CE2 1 
ATOM   2758 C CE3 . TRP   A 1 371 ? 192.191 189.405 154.483 1.00 47.02 ?  371 TRP   A CE3 1 
ATOM   2759 C CZ2 . TRP   A 1 371 ? 193.385 186.879 154.035 1.00 47.02 ?  371 TRP   A CZ2 1 
ATOM   2760 C CZ3 . TRP   A 1 371 ? 192.713 188.658 155.522 1.00 47.02 ?  371 TRP   A CZ3 1 
ATOM   2761 C CH2 . TRP   A 1 371 ? 193.303 187.410 155.293 1.00 47.02 ?  371 TRP   A CH2 1 
ATOM   2762 N N   . ARG   A 1 372 ? 187.844 191.817 150.845 1.00 45.39 ?  372 ARG   A N   1 
ATOM   2763 C CA  . ARG   A 1 372 ? 187.135 192.982 150.333 1.00 45.39 ?  372 ARG   A CA  1 
ATOM   2764 C C   . ARG   A 1 372 ? 186.064 193.411 151.327 1.00 45.39 ?  372 ARG   A C   1 
ATOM   2765 O O   . ARG   A 1 372 ? 185.199 192.613 151.701 1.00 45.39 ?  372 ARG   A O   1 
ATOM   2766 C CB  . ARG   A 1 372 ? 186.501 192.672 148.978 1.00 45.39 ?  372 ARG   A CB  1 
ATOM   2767 C CG  . ARG   A 1 372 ? 185.851 193.872 148.307 1.00 45.39 ?  372 ARG   A CG  1 
ATOM   2768 C CD  . ARG   A 1 372 ? 186.889 194.858 147.794 1.00 45.39 ?  372 ARG   A CD  1 
ATOM   2769 N NE  . ARG   A 1 372 ? 187.126 195.945 148.736 1.00 45.39 ?  372 ARG   A NE  1 
ATOM   2770 C CZ  . ARG   A 1 372 ? 188.090 196.846 148.611 1.00 45.39 ?  372 ARG   A CZ  1 
ATOM   2771 N NH1 . ARG   A 1 372 ? 188.932 196.822 147.590 1.00 45.39 1  372 ARG   A NH1 1 
ATOM   2772 N NH2 . ARG   A 1 372 ? 188.214 197.796 149.534 1.00 45.39 ?  372 ARG   A NH2 1 
ATOM   2773 N N   . ILE   A 1 373 ? 186.117 194.676 151.741 1.00 44.06 ?  373 ILE   A N   1 
ATOM   2774 C CA  . ILE   A 1 373 ? 185.168 195.209 152.703 1.00 44.06 ?  373 ILE   A CA  1 
ATOM   2775 C C   . ILE   A 1 373 ? 184.070 196.033 152.037 1.00 44.06 ?  373 ILE   A C   1 
ATOM   2776 O O   . ILE   A 1 373 ? 182.955 196.095 152.567 1.00 44.06 ?  373 ILE   A O   1 
ATOM   2777 C CB  . ILE   A 1 373 ? 185.893 196.046 153.779 1.00 44.06 ?  373 ILE   A CB  1 
ATOM   2778 C CG1 . ILE   A 1 373 ? 187.110 195.296 154.327 1.00 44.06 ?  373 ILE   A CG1 1 
ATOM   2779 C CG2 . ILE   A 1 373 ? 184.946 196.393 154.919 1.00 44.06 ?  373 ILE   A CG2 1 
ATOM   2780 C CD1 . ILE   A 1 373 ? 187.972 196.129 155.249 1.00 44.06 ?  373 ILE   A CD1 1 
ATOM   2781 N N   . ASP   A 1 374 ? 184.346 196.664 150.899 1.00 45.25 ?  374 ASP   A N   1 
ATOM   2782 C CA  . ASP   A 1 374 ? 183.356 197.493 150.224 1.00 45.25 ?  374 ASP   A CA  1 
ATOM   2783 C C   . ASP   A 1 374 ? 182.277 196.607 149.613 1.00 45.25 ?  374 ASP   A C   1 
ATOM   2784 O O   . ASP   A 1 374 ? 182.587 195.614 148.945 1.00 45.25 ?  374 ASP   A O   1 
ATOM   2785 C CB  . ASP   A 1 374 ? 184.024 198.346 149.149 1.00 45.25 ?  374 ASP   A CB  1 
ATOM   2786 C CG  . ASP   A 1 374 ? 184.874 199.456 149.732 1.00 45.25 ?  374 ASP   A CG  1 
ATOM   2787 O OD1 . ASP   A 1 374 ? 184.546 199.941 150.835 1.00 45.25 ?  374 ASP   A OD1 1 
ATOM   2788 O OD2 . ASP   A 1 374 ? 185.870 199.844 149.087 1.00 45.25 -1 374 ASP   A OD2 1 
ATOM   2789 N N   . ARG   A 1 375 ? 181.016 196.960 149.842 1.00 40.49 ?  375 ARG   A N   1 
ATOM   2790 C CA  . ARG   A 1 375 ? 179.896 196.191 149.330 1.00 40.49 ?  375 ARG   A CA  1 
ATOM   2791 C C   . ARG   A 1 375 ? 178.758 197.119 148.930 1.00 40.49 ?  375 ARG   A C   1 
ATOM   2792 O O   . ARG   A 1 375 ? 178.599 198.196 149.514 1.00 40.49 ?  375 ARG   A O   1 
ATOM   2793 C CB  . ARG   A 1 375 ? 179.394 195.194 150.383 1.00 40.49 ?  375 ARG   A CB  1 
ATOM   2794 C CG  . ARG   A 1 375 ? 180.017 193.813 150.284 1.00 40.49 ?  375 ARG   A CG  1 
ATOM   2795 C CD  . ARG   A 1 375 ? 179.556 192.920 151.423 1.00 40.49 ?  375 ARG   A CD  1 
ATOM   2796 N NE  . ARG   A 1 375 ? 180.568 192.788 152.464 1.00 40.49 ?  375 ARG   A NE  1 
ATOM   2797 C CZ  . ARG   A 1 375 ? 181.680 192.077 152.341 1.00 40.49 ?  375 ARG   A CZ  1 
ATOM   2798 N NH1 . ARG   A 1 375 ? 181.952 191.403 151.236 1.00 40.49 1  375 ARG   A NH1 1 
ATOM   2799 N NH2 . ARG   A 1 375 ? 182.540 192.038 153.354 1.00 40.49 ?  375 ARG   A NH2 1 
ATOM   2800 N N   . PRO   A 1 376 ? 177.952 196.729 147.947 1.00 37.31 ?  376 PRO   A N   1 
ATOM   2801 C CA  . PRO   A 1 376 ? 176.732 197.476 147.628 1.00 37.31 ?  376 PRO   A CA  1 
ATOM   2802 C C   . PRO   A 1 376 ? 175.606 197.058 148.569 1.00 37.31 ?  376 PRO   A C   1 
ATOM   2803 O O   . PRO   A 1 376 ? 175.775 196.193 149.424 1.00 37.31 ?  376 PRO   A O   1 
ATOM   2804 C CB  . PRO   A 1 376 ? 176.448 197.073 146.185 1.00 37.31 ?  376 PRO   A CB  1 
ATOM   2805 C CG  . PRO   A 1 376 ? 176.964 195.682 146.098 1.00 37.31 ?  376 PRO   A CG  1 
ATOM   2806 C CD  . PRO   A 1 376 ? 178.158 195.606 147.015 1.00 37.31 ?  376 PRO   A CD  1 
ATOM   2807 N N   . TRP   A 1 377 ? 174.440 197.680 148.395 1.00 33.37 ?  377 TRP   A N   1 
ATOM   2808 C CA  . TRP   A 1 377 ? 173.361 197.441 149.349 1.00 33.37 ?  377 TRP   A CA  1 
ATOM   2809 C C   . TRP   A 1 377 ? 173.049 195.960 149.482 1.00 33.37 ?  377 TRP   A C   1 
ATOM   2810 O O   . TRP   A 1 377 ? 172.933 195.486 150.624 1.00 33.37 ?  377 TRP   A O   1 
ATOM   2811 C CB  . TRP   A 1 377 ? 172.078 198.195 148.970 1.00 33.37 ?  377 TRP   A CB  1 
ATOM   2812 C CG  . TRP   A 1 377 ? 172.241 199.577 148.464 1.00 33.37 ?  377 TRP   A CG  1 
ATOM   2813 C CD1 . TRP   A 1 377 ? 173.350 200.363 148.537 1.00 33.37 ?  377 TRP   A CD1 1 
ATOM   2814 C CD2 . TRP   A 1 377 ? 171.240 200.357 147.814 1.00 33.37 ?  377 TRP   A CD2 1 
ATOM   2815 N NE1 . TRP   A 1 377 ? 173.107 201.579 147.955 1.00 33.37 ?  377 TRP   A NE1 1 
ATOM   2816 C CE2 . TRP   A 1 377 ? 171.814 201.601 147.505 1.00 33.37 ?  377 TRP   A CE2 1 
ATOM   2817 C CE3 . TRP   A 1 377 ? 169.912 200.122 147.457 1.00 33.37 ?  377 TRP   A CE3 1 
ATOM   2818 C CZ2 . TRP   A 1 377 ? 171.105 202.609 146.857 1.00 33.37 ?  377 TRP   A CZ2 1 
ATOM   2819 C CZ3 . TRP   A 1 377 ? 169.211 201.121 146.812 1.00 33.37 ?  377 TRP   A CZ3 1 
ATOM   2820 C CH2 . TRP   A 1 377 ? 169.807 202.348 146.520 1.00 33.37 ?  377 TRP   A CH2 1 
ATOM   2821 N N   . PRO   A 1 378 ? 172.906 195.185 148.404 1.00 37.49 ?  378 PRO   A N   1 
ATOM   2822 C CA  . PRO   A 1 378 ? 172.521 193.777 148.589 1.00 37.49 ?  378 PRO   A CA  1 
ATOM   2823 C C   . PRO   A 1 378 ? 173.544 192.975 149.370 1.00 37.49 ?  378 PRO   A C   1 
ATOM   2824 O O   . PRO   A 1 378 ? 173.209 192.400 150.412 1.00 37.49 ?  378 PRO   A O   1 
ATOM   2825 C CB  . PRO   A 1 378 ? 172.371 193.263 147.147 1.00 37.49 ?  378 PRO   A CB  1 
ATOM   2826 C CG  . PRO   A 1 378 ? 172.198 194.491 146.312 1.00 37.49 ?  378 PRO   A CG  1 
ATOM   2827 C CD  . PRO   A 1 378 ? 173.034 195.532 146.980 1.00 37.49 ?  378 PRO   A CD  1 
ATOM   2828 N N   . LEU   A 1 379 ? 174.792 192.938 148.908 1.00 38.80 ?  379 LEU   A N   1 
ATOM   2829 C CA  . LEU   A 1 379 ? 175.803 192.084 149.514 1.00 38.80 ?  379 LEU   A CA  1 
ATOM   2830 C C   . LEU   A 1 379 ? 176.199 192.533 150.911 1.00 38.80 ?  379 LEU   A C   1 
ATOM   2831 O O   . LEU   A 1 379 ? 176.788 191.742 151.656 1.00 38.80 ?  379 LEU   A O   1 
ATOM   2832 C CB  . LEU   A 1 379 ? 177.052 192.031 148.628 1.00 38.80 ?  379 LEU   A CB  1 
ATOM   2833 C CG  . LEU   A 1 379 ? 176.801 191.893 147.124 1.00 38.80 ?  379 LEU   A CG  1 
ATOM   2834 C CD1 . LEU   A 1 379 ? 178.111 191.925 146.349 1.00 38.80 ?  379 LEU   A CD1 1 
ATOM   2835 C CD2 . LEU   A 1 379 ? 176.018 190.622 146.829 1.00 38.80 ?  379 LEU   A CD2 1 
ATOM   2836 N N   . ALA   A 1 380 ? 175.896 193.776 151.282 1.00 38.40 ?  380 ALA   A N   1 
ATOM   2837 C CA  . ALA   A 1 380 ? 176.172 194.265 152.626 1.00 38.40 ?  380 ALA   A CA  1 
ATOM   2838 C C   . ALA   A 1 380 ? 174.989 194.039 153.556 1.00 38.40 ?  380 ALA   A C   1 
ATOM   2839 O O   . ALA   A 1 380 ? 175.142 193.458 154.633 1.00 38.40 ?  380 ALA   A O   1 
ATOM   2840 C CB  . ALA   A 1 380 ? 176.526 195.754 152.585 1.00 38.40 ?  380 ALA   A CB  1 
ATOM   2841 N N   . TRP   A 1 381 ? 173.804 194.489 153.148 1.00 37.36 ?  381 TRP   A N   1 
ATOM   2842 C CA  . TRP   A 1 381 ? 172.626 194.345 153.991 1.00 37.36 ?  381 TRP   A CA  1 
ATOM   2843 C C   . TRP   A 1 381 ? 172.311 192.876 154.235 1.00 37.36 ?  381 TRP   A C   1 
ATOM   2844 O O   . TRP   A 1 381 ? 172.012 192.475 155.365 1.00 37.36 ?  381 TRP   A O   1 
ATOM   2845 C CB  . TRP   A 1 381 ? 171.438 195.056 153.345 1.00 37.36 ?  381 TRP   A CB  1 
ATOM   2846 C CG  . TRP   A 1 381 ? 171.561 196.547 153.344 1.00 37.36 ?  381 TRP   A CG  1 
ATOM   2847 C CD1 . TRP   A 1 381 ? 172.714 197.271 153.339 1.00 37.36 ?  381 TRP   A CD1 1 
ATOM   2848 C CD2 . TRP   A 1 381 ? 170.491 197.499 153.329 1.00 37.36 ?  381 TRP   A CD2 1 
ATOM   2849 N NE1 . TRP   A 1 381 ? 172.433 198.613 153.330 1.00 37.36 ?  381 TRP   A NE1 1 
ATOM   2850 C CE2 . TRP   A 1 381 ? 171.073 198.781 153.322 1.00 37.36 ?  381 TRP   A CE2 1 
ATOM   2851 C CE3 . TRP   A 1 381 ? 169.097 197.392 153.322 1.00 37.36 ?  381 TRP   A CE3 1 
ATOM   2852 C CZ2 . TRP   A 1 381 ? 170.311 199.949 153.311 1.00 37.36 ?  381 TRP   A CZ2 1 
ATOM   2853 C CZ3 . TRP   A 1 381 ? 168.341 198.553 153.312 1.00 37.36 ?  381 TRP   A CZ3 1 
ATOM   2854 C CH2 . TRP   A 1 381 ? 168.951 199.814 153.306 1.00 37.36 ?  381 TRP   A CH2 1 
ATOM   2855 N N   . ALA   A 1 382 ? 172.383 192.048 153.189 1.00 39.16 ?  382 ALA   A N   1 
ATOM   2856 C CA  . ALA   A 1 382 ? 172.181 190.621 153.383 1.00 39.16 ?  382 ALA   A CA  1 
ATOM   2857 C C   . ALA   A 1 382 ? 173.283 190.005 154.231 1.00 39.16 ?  382 ALA   A C   1 
ATOM   2858 O O   . ALA   A 1 382 ? 173.127 188.872 154.699 1.00 39.16 ?  382 ALA   A O   1 
ATOM   2859 C CB  . ALA   A 1 382 ? 172.102 189.915 152.030 1.00 39.16 ?  382 ALA   A CB  1 
ATOM   2860 N N   . GLY   A 1 383 ? 174.394 190.717 154.429 1.00 38.44 ?  383 GLY   A N   1 
ATOM   2861 C CA  . GLY   A 1 383 ? 175.432 190.255 155.332 1.00 38.44 ?  383 GLY   A CA  1 
ATOM   2862 C C   . GLY   A 1 383 ? 175.088 190.410 156.796 1.00 38.44 ?  383 GLY   A C   1 
ATOM   2863 O O   . GLY   A 1 383 ? 175.768 189.820 157.642 1.00 38.44 ?  383 GLY   A O   1 
ATOM   2864 N N   . LEU   A 1 384 ? 174.054 191.181 157.111 1.00 38.76 ?  384 LEU   A N   1 
ATOM   2865 C CA  . LEU   A 1 384 ? 173.564 191.317 158.471 1.00 38.76 ?  384 LEU   A CA  1 
ATOM   2866 C C   . LEU   A 1 384 ? 172.517 190.265 158.812 1.00 38.76 ?  384 LEU   A C   1 
ATOM   2867 O O   . LEU   A 1 384 ? 171.750 190.453 159.759 1.00 38.76 ?  384 LEU   A O   1 
ATOM   2868 C CB  . LEU   A 1 384 ? 172.987 192.721 158.674 1.00 38.76 ?  384 LEU   A CB  1 
ATOM   2869 C CG  . LEU   A 1 384 ? 173.994 193.840 158.953 1.00 38.76 ?  384 LEU   A CG  1 
ATOM   2870 C CD1 . LEU   A 1 384 ? 173.505 195.165 158.395 1.00 38.76 ?  384 LEU   A CD1 1 
ATOM   2871 C CD2 . LEU   A 1 384 ? 174.253 193.961 160.446 1.00 38.76 ?  384 LEU   A CD2 1 
ATOM   2872 N N   . VAL   A 1 385 ? 172.481 189.153 158.076 1.00 39.40 ?  385 VAL   A N   1 
ATOM   2873 C CA  . VAL   A 1 385 ? 171.354 188.226 158.181 1.00 39.40 ?  385 VAL   A CA  1 
ATOM   2874 C C   . VAL   A 1 385 ? 171.329 187.551 159.549 1.00 39.40 ?  385 VAL   A C   1 
ATOM   2875 O O   . VAL   A 1 385 ? 170.329 187.618 160.274 1.00 39.40 ?  385 VAL   A O   1 
ATOM   2876 C CB  . VAL   A 1 385 ? 171.396 187.196 157.036 1.00 39.40 ?  385 VAL   A CB  1 
ATOM   2877 C CG1 . VAL   A 1 385 ? 172.689 186.388 157.057 1.00 39.40 ?  385 VAL   A CG1 1 
ATOM   2878 C CG2 . VAL   A 1 385 ? 170.193 186.274 157.114 1.00 39.40 ?  385 VAL   A CG2 1 
ATOM   2879 N N   . ASP   A 1 386 ? 172.420 186.878 159.920 1.00 39.43 ?  386 ASP   A N   1 
ATOM   2880 C CA  . ASP   A 1 386 ? 172.426 186.150 161.183 1.00 39.43 ?  386 ASP   A CA  1 
ATOM   2881 C C   . ASP   A 1 386 ? 172.394 187.110 162.362 1.00 39.43 ?  386 ASP   A C   1 
ATOM   2882 O O   . ASP   A 1 386 ? 171.789 186.810 163.397 1.00 39.43 ?  386 ASP   A O   1 
ATOM   2883 C CB  . ASP   A 1 386 ? 173.649 185.236 161.264 1.00 39.43 ?  386 ASP   A CB  1 
ATOM   2884 C CG  . ASP   A 1 386 ? 173.359 183.819 160.788 1.00 39.43 ?  386 ASP   A CG  1 
ATOM   2885 O OD1 . ASP   A 1 386 ? 172.176 183.434 160.716 1.00 39.43 ?  386 ASP   A OD1 1 
ATOM   2886 O OD2 . ASP   A 1 386 ? 174.323 183.086 160.482 1.00 39.43 -1 386 ASP   A OD2 1 
ATOM   2887 N N   . ILE   A 1 387 ? 173.028 188.274 162.221 1.00 39.95 ?  387 ILE   A N   1 
ATOM   2888 C CA  . ILE   A 1 387 ? 172.958 189.286 163.271 1.00 39.95 ?  387 ILE   A CA  1 
ATOM   2889 C C   . ILE   A 1 387 ? 171.512 189.708 163.496 1.00 39.95 ?  387 ILE   A C   1 
ATOM   2890 O O   . ILE   A 1 387 ? 171.041 189.793 164.636 1.00 39.95 ?  387 ILE   A O   1 
ATOM   2891 C CB  . ILE   A 1 387 ? 173.844 190.491 162.913 1.00 39.95 ?  387 ILE   A CB  1 
ATOM   2892 C CG1 . ILE   A 1 387 ? 175.311 190.073 162.880 1.00 39.95 ?  387 ILE   A CG1 1 
ATOM   2893 C CG2 . ILE   A 1 387 ? 173.627 191.618 163.903 1.00 39.95 ?  387 ILE   A CG2 1 
ATOM   2894 C CD1 . ILE   A 1 387 ? 176.213 191.088 162.236 1.00 39.95 ?  387 ILE   A CD1 1 
ATOM   2895 N N   . VAL   A 1 388 ? 170.783 189.969 162.410 1.00 40.55 ?  388 VAL   A N   1 
ATOM   2896 C CA  . VAL   A 1 388 ? 169.396 190.396 162.532 1.00 40.55 ?  388 VAL   A CA  1 
ATOM   2897 C C   . VAL   A 1 388 ? 168.549 189.285 163.129 1.00 40.55 ?  388 VAL   A C   1 
ATOM   2898 O O   . VAL   A 1 388 ? 167.669 189.539 163.952 1.00 40.55 ?  388 VAL   A O   1 
ATOM   2899 C CB  . VAL   A 1 388 ? 168.856 190.846 161.163 1.00 40.55 ?  388 VAL   A CB  1 
ATOM   2900 C CG1 . VAL   A 1 388 ? 167.337 190.892 161.179 1.00 40.55 ?  388 VAL   A CG1 1 
ATOM   2901 C CG2 . VAL   A 1 388 ? 169.427 192.203 160.792 1.00 40.55 ?  388 VAL   A CG2 1 
ATOM   2902 N N   . ALA   A 1 389 ? 168.785 188.039 162.714 1.00 41.34 ?  389 ALA   A N   1 
ATOM   2903 C CA  . ALA   A 1 389 ? 168.010 186.929 163.262 1.00 41.34 ?  389 ALA   A CA  1 
ATOM   2904 C C   . ALA   A 1 389 ? 168.242 186.794 164.761 1.00 41.34 ?  389 ALA   A C   1 
ATOM   2905 O O   . ALA   A 1 389 ? 167.293 186.632 165.539 1.00 41.34 ?  389 ALA   A O   1 
ATOM   2906 C CB  . ALA   A 1 389 ? 168.369 185.630 162.539 1.00 41.34 ?  389 ALA   A CB  1 
ATOM   2907 N N   . ALA   A 1 390 ? 169.503 186.870 165.189 1.00 41.34 ?  390 ALA   A N   1 
ATOM   2908 C CA  . ALA   A 1 390 ? 169.804 186.764 166.610 1.00 41.34 ?  390 ALA   A CA  1 
ATOM   2909 C C   . ALA   A 1 390 ? 169.201 187.925 167.389 1.00 41.34 ?  390 ALA   A C   1 
ATOM   2910 O O   . ALA   A 1 390 ? 168.661 187.731 168.484 1.00 41.34 ?  390 ALA   A O   1 
ATOM   2911 C CB  . ALA   A 1 390 ? 171.315 186.703 166.821 1.00 41.34 ?  390 ALA   A CB  1 
ATOM   2912 N N   . ILE   A 1 391 ? 169.278 189.140 166.841 1.00 42.02 ?  391 ILE   A N   1 
ATOM   2913 C CA  . ILE   A 1 391 ? 168.735 190.297 167.543 1.00 42.02 ?  391 ILE   A CA  1 
ATOM   2914 C C   . ILE   A 1 391 ? 167.218 190.214 167.616 1.00 42.02 ?  391 ILE   A C   1 
ATOM   2915 O O   . ILE   A 1 391 ? 166.612 190.597 168.622 1.00 42.02 ?  391 ILE   A O   1 
ATOM   2916 C CB  . ILE   A 1 391 ? 169.202 191.598 166.866 1.00 42.02 ?  391 ILE   A CB  1 
ATOM   2917 C CG1 . ILE   A 1 391 ? 170.721 191.757 166.998 1.00 42.02 ?  391 ILE   A CG1 1 
ATOM   2918 C CG2 . ILE   A 1 391 ? 168.474 192.794 167.458 1.00 42.02 ?  391 ILE   A CG2 1 
ATOM   2919 C CD1 . ILE   A 1 391 ? 171.215 191.910 168.424 1.00 42.02 ?  391 ILE   A CD1 1 
ATOM   2920 N N   . ALA   A 1 392 ? 166.577 189.723 166.555 1.00 41.94 ?  392 ALA   A N   1 
ATOM   2921 C CA  . ALA   A 1 392 ? 165.132 189.542 166.580 1.00 41.94 ?  392 ALA   A CA  1 
ATOM   2922 C C   . ALA   A 1 392 ? 164.732 188.514 167.624 1.00 41.94 ?  392 ALA   A C   1 
ATOM   2923 O O   . ALA   A 1 392 ? 163.761 188.714 168.361 1.00 41.94 ?  392 ALA   A O   1 
ATOM   2924 C CB  . ALA   A 1 392 ? 164.631 189.126 165.199 1.00 41.94 ?  392 ALA   A CB  1 
ATOM   2925 N N   . THR   A 1 393 ? 165.467 187.405 167.707 1.00 42.26 ?  393 THR   A N   1 
ATOM   2926 C CA  . THR   A 1 393 ? 165.167 186.415 168.734 1.00 42.26 ?  393 THR   A CA  1 
ATOM   2927 C C   . THR   A 1 393 ? 165.347 187.002 170.126 1.00 42.26 ?  393 THR   A C   1 
ATOM   2928 O O   . THR   A 1 393 ? 164.519 186.774 171.016 1.00 42.26 ?  393 THR   A O   1 
ATOM   2929 C CB  . THR   A 1 393 ? 166.053 185.185 168.561 1.00 42.26 ?  393 THR   A CB  1 
ATOM   2930 O OG1 . THR   A 1 393 ? 165.907 184.669 167.233 1.00 42.26 ?  393 THR   A OG1 1 
ATOM   2931 C CG2 . THR   A 1 393 ? 165.666 184.115 169.560 1.00 42.26 ?  393 THR   A CG2 1 
ATOM   2932 N N   . LEU   A 1 394 ? 166.422 187.763 170.337 1.00 43.31 ?  394 LEU   A N   1 
ATOM   2933 C CA  . LEU   A 1 394 ? 166.652 188.363 171.646 1.00 43.31 ?  394 LEU   A CA  1 
ATOM   2934 C C   . LEU   A 1 394 ? 165.542 189.344 172.008 1.00 43.31 ?  394 LEU   A C   1 
ATOM   2935 O O   . LEU   A 1 394 ? 165.042 189.337 173.139 1.00 43.31 ?  394 LEU   A O   1 
ATOM   2936 C CB  . LEU   A 1 394 ? 168.010 189.062 171.669 1.00 43.31 ?  394 LEU   A CB  1 
ATOM   2937 C CG  . LEU   A 1 394 ? 169.230 188.138 171.658 1.00 43.31 ?  394 LEU   A CG  1 
ATOM   2938 C CD1 . LEU   A 1 394 ? 170.508 188.941 171.472 1.00 43.31 ?  394 LEU   A CD1 1 
ATOM   2939 C CD2 . LEU   A 1 394 ? 169.292 187.313 172.931 1.00 43.31 ?  394 LEU   A CD2 1 
ATOM   2940 N N   . THR   A 1 395 ? 165.143 190.197 171.061 1.00 43.03 ?  395 THR   A N   1 
ATOM   2941 C CA  . THR   A 1 395 ? 164.074 191.154 171.326 1.00 43.03 ?  395 THR   A CA  1 
ATOM   2942 C C   . THR   A 1 395 ? 162.756 190.444 171.595 1.00 43.03 ?  395 THR   A C   1 
ATOM   2943 O O   . THR   A 1 395 ? 161.993 190.848 172.481 1.00 43.03 ?  395 THR   A O   1 
ATOM   2944 C CB  . THR   A 1 395 ? 163.927 192.115 170.147 1.00 43.03 ?  395 THR   A CB  1 
ATOM   2945 O OG1 . THR   A 1 395 ? 165.050 193.003 170.107 1.00 43.03 ?  395 THR   A OG1 1 
ATOM   2946 C CG2 . THR   A 1 395 ? 162.646 192.926 170.273 1.00 43.03 ?  395 THR   A CG2 1 
ATOM   2947 N N   . TRP   A 1 396 ? 162.462 189.392 170.830 1.00 43.30 ?  396 TRP   A N   1 
ATOM   2948 C CA  . TRP   A 1 396 ? 161.237 188.639 171.058 1.00 43.30 ?  396 TRP   A CA  1 
ATOM   2949 C C   . TRP   A 1 396 ? 161.236 188.018 172.447 1.00 43.30 ?  396 TRP   A C   1 
ATOM   2950 O O   . TRP   A 1 396 ? 160.231 188.081 173.164 1.00 43.30 ?  396 TRP   A O   1 
ATOM   2951 C CB  . TRP   A 1 396 ? 161.081 187.566 169.981 1.00 43.30 ?  396 TRP   A CB  1 
ATOM   2952 C CG  . TRP   A 1 396 ? 160.056 186.533 170.306 1.00 43.30 ?  396 TRP   A CG  1 
ATOM   2953 C CD1 . TRP   A 1 396 ? 158.707 186.646 170.164 1.00 43.30 ?  396 TRP   A CD1 1 
ATOM   2954 C CD2 . TRP   A 1 396 ? 160.297 185.225 170.828 1.00 43.30 ?  396 TRP   A CD2 1 
ATOM   2955 N NE1 . TRP   A 1 396 ? 158.091 185.489 170.567 1.00 43.30 ?  396 TRP   A NE1 1 
ATOM   2956 C CE2 . TRP   A 1 396 ? 159.047 184.600 170.980 1.00 43.30 ?  396 TRP   A CE2 1 
ATOM   2957 C CE3 . TRP   A 1 396 ? 161.449 184.522 171.184 1.00 43.30 ?  396 TRP   A CE3 1 
ATOM   2958 C CZ2 . TRP   A 1 396 ? 158.916 183.307 171.471 1.00 43.30 ?  396 TRP   A CZ2 1 
ATOM   2959 C CZ3 . TRP   A 1 396 ? 161.318 183.239 171.672 1.00 43.30 ?  396 TRP   A CZ3 1 
ATOM   2960 C CH2 . TRP   A 1 396 ? 160.061 182.644 171.811 1.00 43.30 ?  396 TRP   A CH2 1 
ATOM   2961 N N   . MET   A 1 397 ? 162.358 187.422 172.851 1.00 43.73 ?  397 MET   A N   1 
ATOM   2962 C CA  . MET   A 1 397 ? 162.431 186.840 174.184 1.00 43.73 ?  397 MET   A CA  1 
ATOM   2963 C C   . MET   A 1 397 ? 162.262 187.909 175.251 1.00 43.73 ?  397 MET   A C   1 
ATOM   2964 O O   . MET   A 1 397 ? 161.553 187.702 176.242 1.00 43.73 ?  397 MET   A O   1 
ATOM   2965 C CB  . MET   A 1 397 ? 163.755 186.103 174.364 1.00 43.73 ?  397 MET   A CB  1 
ATOM   2966 C CG  . MET   A 1 397 ? 163.854 184.824 173.555 1.00 43.73 ?  397 MET   A CG  1 
ATOM   2967 S SD  . MET   A 1 397 ? 165.429 183.982 173.771 1.00 43.73 ?  397 MET   A SD  1 
ATOM   2968 C CE  . MET   A 1 397 ? 165.256 183.395 175.450 1.00 43.73 ?  397 MET   A CE  1 
ATOM   2969 N N   . ALA   A 1 398 ? 162.892 189.069 175.060 1.00 44.93 ?  398 ALA   A N   1 
ATOM   2970 C CA  . ALA   A 1 398 ? 162.783 190.138 176.047 1.00 44.93 ?  398 ALA   A CA  1 
ATOM   2971 C C   . ALA   A 1 398 ? 161.342 190.609 176.190 1.00 44.93 ?  398 ALA   A C   1 
ATOM   2972 O O   . ALA   A 1 398 ? 160.835 190.764 177.307 1.00 44.93 ?  398 ALA   A O   1 
ATOM   2973 C CB  . ALA   A 1 398 ? 163.694 191.302 175.658 1.00 44.93 ?  398 ALA   A CB  1 
ATOM   2974 N N   . VAL   A 1 399 ? 160.658 190.829 175.065 1.00 44.15 ?  399 VAL   A N   1 
ATOM   2975 C CA  . VAL   A 1 399 ? 159.301 191.362 175.124 1.00 44.15 ?  399 VAL   A CA  1 
ATOM   2976 C C   . VAL   A 1 399 ? 158.336 190.321 175.675 1.00 44.15 ?  399 VAL   A C   1 
ATOM   2977 O O   . VAL   A 1 399 ? 157.434 190.647 176.454 1.00 44.15 ?  399 VAL   A O   1 
ATOM   2978 C CB  . VAL   A 1 399 ? 158.860 191.871 173.740 1.00 44.15 ?  399 VAL   A CB  1 
ATOM   2979 C CG1 . VAL   A 1 399 ? 158.797 190.735 172.738 1.00 44.15 ?  399 VAL   A CG1 1 
ATOM   2980 C CG2 . VAL   A 1 399 ? 157.515 192.573 173.843 1.00 44.15 ?  399 VAL   A CG2 1 
ATOM   2981 N N   . VAL   A 1 400 ? 158.503 189.053 175.289 1.00 43.91 ?  400 VAL   A N   1 
ATOM   2982 C CA  . VAL   A 1 400 ? 157.602 188.025 175.797 1.00 43.91 ?  400 VAL   A CA  1 
ATOM   2983 C C   . VAL   A 1 400 ? 157.824 187.808 177.288 1.00 43.91 ?  400 VAL   A C   1 
ATOM   2984 O O   . VAL   A 1 400 ? 156.865 187.571 178.032 1.00 43.91 ?  400 VAL   A O   1 
ATOM   2985 C CB  . VAL   A 1 400 ? 157.763 186.718 174.999 1.00 43.91 ?  400 VAL   A CB  1 
ATOM   2986 C CG1 . VAL   A 1 400 ? 159.032 185.996 175.384 1.00 43.91 ?  400 VAL   A CG1 1 
ATOM   2987 C CG2 . VAL   A 1 400 ? 156.561 185.823 175.214 1.00 43.91 ?  400 VAL   A CG2 1 
ATOM   2988 N N   . GLY   A 1 401 ? 159.072 187.881 177.757 1.00 44.13 ?  401 GLY   A N   1 
ATOM   2989 C CA  . GLY   A 1 401 ? 159.310 187.785 179.187 1.00 44.13 ?  401 GLY   A CA  1 
ATOM   2990 C C   . GLY   A 1 401 ? 158.738 188.963 179.950 1.00 44.13 ?  401 GLY   A C   1 
ATOM   2991 O O   . GLY   A 1 401 ? 158.096 188.787 180.989 1.00 44.13 ?  401 GLY   A O   1 
ATOM   2992 N N   . ARG   A 1 402 ? 158.952 190.180 179.443 1.00 45.51 ?  402 ARG   A N   1 
ATOM   2993 C CA  . ARG   A 1 402 ? 158.438 191.361 180.127 1.00 45.51 ?  402 ARG   A CA  1 
ATOM   2994 C C   . ARG   A 1 402 ? 156.918 191.340 180.192 1.00 45.51 ?  402 ARG   A C   1 
ATOM   2995 O O   . ARG   A 1 402 ? 156.331 191.662 181.231 1.00 45.51 ?  402 ARG   A O   1 
ATOM   2996 C CB  . ARG   A 1 402 ? 158.932 192.626 179.423 1.00 45.51 ?  402 ARG   A CB  1 
ATOM   2997 C CG  . ARG   A 1 402 ? 158.198 193.897 179.820 1.00 45.51 ?  402 ARG   A CG  1 
ATOM   2998 C CD  . ARG   A 1 402 ? 158.876 195.127 179.237 1.00 45.51 ?  402 ARG   A CD  1 
ATOM   2999 N NE  . ARG   A 1 402 ? 158.699 195.216 177.792 1.00 45.51 ?  402 ARG   A NE  1 
ATOM   3000 C CZ  . ARG   A 1 402 ? 159.585 195.733 176.950 1.00 45.51 ?  402 ARG   A CZ  1 
ATOM   3001 N NH1 . ARG   A 1 402 ? 160.736 196.231 177.373 1.00 45.51 1  402 ARG   A NH1 1 
ATOM   3002 N NH2 . ARG   A 1 402 ? 159.309 195.754 175.650 1.00 45.51 ?  402 ARG   A NH2 1 
ATOM   3003 N N   . ARG   A 1 403 ? 156.260 190.965 179.093 1.00 45.07 ?  403 ARG   A N   1 
ATOM   3004 C CA  . ARG   A 1 403 ? 154.805 190.871 179.109 1.00 45.07 ?  403 ARG   A CA  1 
ATOM   3005 C C   . ARG   A 1 403 ? 154.338 189.809 180.095 1.00 45.07 ?  403 ARG   A C   1 
ATOM   3006 O O   . ARG   A 1 403 ? 153.346 190.007 180.807 1.00 45.07 ?  403 ARG   A O   1 
ATOM   3007 C CB  . ARG   A 1 403 ? 154.284 190.569 177.706 1.00 45.07 ?  403 ARG   A CB  1 
ATOM   3008 C CG  . ARG   A 1 403 ? 154.513 191.690 176.705 1.00 45.07 ?  403 ARG   A CG  1 
ATOM   3009 C CD  . ARG   A 1 403 ? 153.633 192.892 177.001 1.00 45.07 ?  403 ARG   A CD  1 
ATOM   3010 N NE  . ARG   A 1 403 ? 154.382 193.969 177.637 1.00 45.07 ?  403 ARG   A NE  1 
ATOM   3011 C CZ  . ARG   A 1 403 ? 155.138 194.843 176.987 1.00 45.07 ?  403 ARG   A CZ  1 
ATOM   3012 N NH1 . ARG   A 1 403 ? 155.273 194.799 175.671 1.00 45.07 1  403 ARG   A NH1 1 
ATOM   3013 N NH2 . ARG   A 1 403 ? 155.777 195.785 177.675 1.00 45.07 ?  403 ARG   A NH2 1 
HETATM 3014 C C4  . A1A8B B 2 .   ? 180.899 173.447 151.778 1.00 40.99 ?  501 A1A8B A C4  1 
HETATM 3015 C C5  . A1A8B B 2 .   ? 178.677 172.837 152.417 1.00 40.99 ?  501 A1A8B A C5  1 
HETATM 3016 C C6  . A1A8B B 2 .   ? 177.006 171.250 151.767 1.00 40.99 ?  501 A1A8B A C6  1 
HETATM 3017 C C7  . A1A8B B 2 .   ? 177.215 169.998 150.954 1.00 40.99 ?  501 A1A8B A C7  1 
HETATM 3018 C C8  . A1A8B B 2 .   ? 175.170 168.819 151.229 1.00 40.99 ?  501 A1A8B A C8  1 
HETATM 3019 C C10 . A1A8B B 2 .   ? 177.200 170.988 153.245 1.00 40.99 ?  501 A1A8B A C10 1 
HETATM 3020 C C13 . A1A8B B 2 .   ? 181.756 174.562 152.346 1.00 40.99 ?  501 A1A8B A C13 1 
HETATM 3021 C C15 . A1A8B B 2 .   ? 181.907 175.612 150.056 1.00 40.99 ?  501 A1A8B A C15 1 
HETATM 3022 C C17 . A1A8B B 2 .   ? 184.627 173.984 149.569 1.00 40.99 ?  501 A1A8B A C17 1 
HETATM 3023 C C20 . A1A8B B 2 .   ? 188.831 173.749 151.139 1.00 40.99 ?  501 A1A8B A C20 1 
HETATM 3024 C C21 . A1A8B B 2 .   ? 189.070 175.901 152.147 1.00 40.99 ?  501 A1A8B A C21 1 
HETATM 3025 C C22 . A1A8B B 2 .   ? 188.188 177.065 151.765 1.00 40.99 ?  501 A1A8B A C22 1 
HETATM 3026 C C24 . A1A8B B 2 .   ? 190.023 179.694 152.204 1.00 40.99 ?  501 A1A8B A C24 1 
HETATM 3027 C C26 . A1A8B B 2 .   ? 189.918 180.803 153.223 1.00 40.99 ?  501 A1A8B A C26 1 
HETATM 3028 C C28 . A1A8B B 2 .   ? 188.830 179.130 154.770 1.00 40.99 ?  501 A1A8B A C28 1 
HETATM 3029 P P1  . A1A8B B 2 .   ? 179.559 172.695 148.210 1.00 40.99 ?  501 A1A8B A P1  1 
HETATM 3030 C C1  . A1A8B B 2 .   ? 175.749 172.403 148.671 1.00 40.99 ?  501 A1A8B A C1  1 
HETATM 3031 O O1  . A1A8B B 2 .   ? 178.121 172.087 148.581 1.00 40.99 ?  501 A1A8B A O1  1 
HETATM 3032 C C2  . A1A8B B 2 .   ? 176.955 172.519 147.830 1.00 40.99 ?  501 A1A8B A C2  1 
HETATM 3033 O O2  . A1A8B B 2 .   ? 180.537 171.575 147.992 1.00 40.99 -1 501 A1A8B A O2  1 
HETATM 3034 C C3  . A1A8B B 2 .   ? 181.173 173.213 150.299 1.00 40.99 ?  501 A1A8B A C3  1 
HETATM 3035 O O3  . A1A8B B 2 .   ? 179.378 173.698 147.105 1.00 40.99 ?  501 A1A8B A O3  1 
HETATM 3036 O O4  . A1A8B B 2 .   ? 179.932 173.467 149.566 1.00 40.99 ?  501 A1A8B A O4  1 
HETATM 3037 O O5  . A1A8B B 2 .   ? 179.527 173.839 151.928 1.00 40.99 ?  501 A1A8B A O5  1 
HETATM 3038 O O6  . A1A8B B 2 .   ? 177.994 172.210 151.338 1.00 40.99 ?  501 A1A8B A O6  1 
HETATM 3039 O O7  . A1A8B B 2 .   ? 176.468 168.923 151.562 1.00 40.99 ?  501 A1A8B A O7  1 
HETATM 3040 O O8  . A1A8B B 2 .   ? 174.713 169.322 150.242 1.00 40.99 ?  501 A1A8B A O8  1 
HETATM 3041 C C9  . A1A8B B 2 .   ? 174.412 168.016 152.225 1.00 40.99 ?  501 A1A8B A C9  1 
HETATM 3042 O O9  . A1A8B B 2 .   ? 176.351 169.928 153.657 1.00 40.99 ?  501 A1A8B A O9  1 
HETATM 3043 O O10 . A1A8B B 2 .   ? 178.821 170.211 154.841 1.00 40.99 ?  501 A1A8B A O10 1 
HETATM 3044 C C11 . A1A8B B 2 .   ? 178.645 170.622 153.489 1.00 40.99 ?  501 A1A8B A C11 1 
HETATM 3045 O O11 . A1A8B B 2 .   ? 180.037 172.414 154.364 1.00 40.99 ?  501 A1A8B A O11 1 
HETATM 3046 C C12 . A1A8B B 2 .   ? 179.513 171.820 153.180 1.00 40.99 ?  501 A1A8B A C12 1 
HETATM 3047 O O12 . A1A8B B 2 .   ? 181.384 174.812 153.699 1.00 40.99 ?  501 A1A8B A O12 1 
HETATM 3048 O O13 . A1A8B B 2 .   ? 182.458 176.847 152.051 1.00 40.99 ?  501 A1A8B A O13 1 
HETATM 3049 C C14 . A1A8B B 2 .   ? 181.595 175.836 151.531 1.00 40.99 ?  501 A1A8B A C14 1 
HETATM 3050 O O14 . A1A8B B 2 .   ? 180.798 176.024 149.258 1.00 40.99 ?  501 A1A8B A O14 1 
HETATM 3051 O O15 . A1A8B B 2 .   ? 183.496 173.848 150.385 1.00 40.99 ?  501 A1A8B A O15 1 
HETATM 3052 C C16 . A1A8B B 2 .   ? 182.241 174.157 149.762 1.00 40.99 ?  501 A1A8B A C16 1 
HETATM 3053 O O16 . A1A8B B 2 .   ? 185.778 173.835 150.368 1.00 40.99 ?  501 A1A8B A O16 1 
HETATM 3054 O O17 . A1A8B B 2 .   ? 187.992 172.638 151.009 1.00 40.99 ?  501 A1A8B A O17 1 
HETATM 3055 C C18 . A1A8B B 2 .   ? 185.627 172.772 151.318 1.00 40.99 ?  501 A1A8B A C18 1 
HETATM 3056 O O18 . A1A8B B 2 .   ? 188.269 174.707 152.011 1.00 40.99 ?  501 A1A8B A O18 1 
HETATM 3057 C C19 . A1A8B B 2 .   ? 186.958 172.580 152.002 1.00 40.99 ?  501 A1A8B A C19 1 
HETATM 3058 O O19 . A1A8B B 2 .   ? 187.987 177.908 152.918 1.00 40.99 ?  501 A1A8B A O19 1 
HETATM 3059 O O20 . A1A8B B 2 .   ? 190.235 178.464 152.907 1.00 40.99 ?  501 A1A8B A O20 1 
HETATM 3060 O O21 . A1A8B B 2 .   ? 190.804 179.636 149.912 1.00 40.99 ?  501 A1A8B A O21 1 
HETATM 3061 O O22 . A1A8B B 2 .   ? 189.717 182.031 152.535 1.00 40.99 ?  501 A1A8B A O22 1 
HETATM 3062 C C23 . A1A8B B 2 .   ? 189.133 178.077 153.706 1.00 40.99 ?  501 A1A8B A C23 1 
HETATM 3063 O O23 . A1A8B B 2 .   ? 188.736 181.498 155.205 1.00 40.99 ?  501 A1A8B A O23 1 
HETATM 3064 O O24 . A1A8B B 2 .   ? 189.835 179.093 155.792 1.00 40.99 ?  501 A1A8B A O24 1 
HETATM 3065 C C25 . A1A8B B 2 .   ? 191.190 179.869 151.263 1.00 40.99 ?  501 A1A8B A C25 1 
HETATM 3066 O O25 . A1A8B B 2 .   ? 188.109 179.913 157.115 1.00 40.99 ?  501 A1A8B A O25 1 
HETATM 3067 O O26 . A1A8B B 2 .   ? 185.132 180.424 158.462 1.00 40.99 ?  501 A1A8B A O26 1 
HETATM 3068 C C27 . A1A8B B 2 .   ? 188.753 180.530 154.156 1.00 40.99 ?  501 A1A8B A C27 1 
HETATM 3069 O O27 . A1A8B B 2 .   ? 189.173 179.408 160.078 1.00 40.99 ?  501 A1A8B A O27 1 
HETATM 3070 O O28 . A1A8B B 2 .   ? 189.112 182.393 157.966 1.00 40.99 ?  501 A1A8B A O28 1 
HETATM 3071 C C29 . A1A8B B 2 .   ? 189.425 179.379 157.107 1.00 40.99 ?  501 A1A8B A C29 1 
HETATM 3072 O O29 . A1A8B B 2 .   ? 190.964 181.150 156.615 1.00 40.99 ?  501 A1A8B A O29 1 
HETATM 3073 C C30 . A1A8B B 2 .   ? 187.540 180.064 158.434 1.00 40.99 ?  501 A1A8B A C30 1 
HETATM 3074 O O30 . A1A8B B 2 .   ? 191.266 174.879 151.888 1.00 40.99 ?  501 A1A8B A O30 1 
HETATM 3075 C C31 . A1A8B B 2 .   ? 186.402 181.051 158.305 1.00 40.99 ?  501 A1A8B A C31 1 
HETATM 3076 O O31 . A1A8B B 2 .   ? 189.634 176.602 149.126 1.00 40.99 ?  501 A1A8B A O31 1 
HETATM 3077 C C32 . A1A8B B 2 .   ? 188.612 180.533 159.410 1.00 40.99 ?  501 A1A8B A C32 1 
HETATM 3078 O O32 . A1A8B B 2 .   ? 187.790 174.871 149.276 1.00 40.99 ?  501 A1A8B A O32 1 
HETATM 3079 C C33 . A1A8B B 2 .   ? 189.691 181.294 158.667 1.00 40.99 ?  501 A1A8B A C33 1 
HETATM 3080 O O33 . A1A8B B 2 .   ? 183.757 171.360 150.927 1.00 40.99 ?  501 A1A8B A O33 1 
HETATM 3081 C C34 . A1A8B B 2 .   ? 190.401 180.391 157.681 1.00 40.99 ?  501 A1A8B A C34 1 
HETATM 3082 O O34 . A1A8B B 2 .   ? 186.655 171.712 148.715 1.00 40.99 ?  501 A1A8B A O34 1 
HETATM 3083 C C35 . A1A8B B 2 .   ? 190.359 175.819 151.305 1.00 40.99 ?  501 A1A8B A C35 1 
HETATM 3084 O O35 . A1A8B B 2 .   ? 185.247 173.322 147.348 1.00 40.99 ?  501 A1A8B A O35 1 
HETATM 3085 C C36 . A1A8B B 2 .   ? 190.072 175.454 149.851 1.00 40.99 ?  501 A1A8B A C36 1 
HETATM 3086 C C37 . A1A8B B 2 .   ? 189.028 174.363 149.763 1.00 40.99 ?  501 A1A8B A C37 1 
HETATM 3087 C C38 . A1A8B B 2 .   ? 185.125 171.527 150.593 1.00 40.99 ?  501 A1A8B A C38 1 
HETATM 3088 C C39 . A1A8B B 2 .   ? 185.279 171.648 149.079 1.00 40.99 ?  501 A1A8B A C39 1 
HETATM 3089 C C40 . A1A8B B 2 .   ? 184.591 172.880 148.531 1.00 40.99 ?  501 A1A8B A C40 1 
HETATM 3090 C C35 . DSL   C 3 .   ? 184.003 188.902 173.639 1.00 0.50  ?  502 DSL   A C35 1 
HETATM 3091 C C36 . DSL   C 3 .   ? 184.749 187.648 173.233 1.00 0.50  ?  502 DSL   A C36 1 
HETATM 3092 C C37 . DSL   C 3 .   ? 184.282 186.412 173.949 1.00 0.50  ?  502 DSL   A C37 1 
HETATM 3093 C C38 . DSL   C 3 .   ? 182.802 186.185 173.927 1.00 0.50  ?  502 DSL   A C38 1 
HETATM 3094 C C39 . DSL   C 3 .   ? 185.145 185.598 174.550 1.00 0.50  ?  502 DSL   A C39 1 
HETATM 3095 C C40 . DSL   C 3 .   ? 186.571 185.873 174.912 1.00 0.50  ?  502 DSL   A C40 1 
HETATM 3096 C C41 . DSL   C 3 .   ? 187.516 185.650 173.751 1.00 0.50  ?  502 DSL   A C41 1 
HETATM 3097 C C42 . DSL   C 3 .   ? 188.891 186.206 173.988 1.00 0.50  ?  502 DSL   A C42 1 
HETATM 3098 C C43 . DSL   C 3 .   ? 189.221 186.493 175.420 1.00 0.50  ?  502 DSL   A C43 1 
HETATM 3099 C C44 . DSL   C 3 .   ? 189.730 186.419 172.979 1.00 0.50  ?  502 DSL   A C44 1 
HETATM 3100 C C45 . DSL   C 3 .   ? 189.482 187.192 171.721 1.00 0.50  ?  502 DSL   A C45 1 
HETATM 3101 C C46 . DSL   C 3 .   ? 190.179 186.586 170.523 1.00 0.50  ?  502 DSL   A C46 1 
HETATM 3102 C C47 . DSL   C 3 .   ? 189.347 186.613 169.273 1.00 0.50  ?  502 DSL   A C47 1 
HETATM 3103 C C48 . DSL   C 3 .   ? 189.612 187.770 168.359 1.00 0.50  ?  502 DSL   A C48 1 
HETATM 3104 C C49 . DSL   C 3 .   ? 188.452 185.663 169.021 1.00 0.50  ?  502 DSL   A C49 1 
HETATM 3105 C C50 . DSL   C 3 .   ? 188.694 184.298 168.458 1.00 0.50  ?  502 DSL   A C50 1 
HETATM 3106 C C51 . DSL   C 3 .   ? 189.438 183.400 169.423 1.00 0.50  ?  502 DSL   A C51 1 
HETATM 3107 C C52 . DSL   C 3 .   ? 190.287 182.366 168.738 1.00 0.50  ?  502 DSL   A C52 1 
HETATM 3108 C C53 . DSL   C 3 .   ? 191.547 181.989 169.456 1.00 0.50  ?  502 DSL   A C53 1 
HETATM 3109 C C54 . DSL   C 3 .   ? 189.929 181.832 167.576 1.00 0.50  ?  502 DSL   A C54 1 
HETATM 3110 C C55 . DSL   C 3 .   ? 190.472 180.544 167.057 1.00 0.50  ?  502 DSL   A C55 1 
HETATM 3111 O O56 . DSL   C 3 .   ? 189.493 179.888 166.259 1.00 0.50  ?  502 DSL   A O56 1 
HETATM 3112 P P57 . DSL   C 3 .   ? 189.378 180.200 164.684 1.00 0.50  ?  502 DSL   A P57 1 
HETATM 3113 O O58 . DSL   C 3 .   ? 189.227 181.703 164.575 1.00 0.50  ?  502 DSL   A O58 1 
HETATM 3114 O O59 . DSL   C 3 .   ? 190.665 179.690 164.072 1.00 0.50  ?  502 DSL   A O59 1 
HETATM 3115 O O60 . DSL   C 3 .   ? 188.158 179.452 164.199 1.00 0.50  ?  502 DSL   A O60 1 
# 
