data_9DK9
# 
_entry.id   9DK9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DK9         pdb_00009dk9 10.2210/pdb9dk9/pdb 
WWPDB D_1000288059 ?            ?                   
EMDB  EMD-46948    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-18 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DK9 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of URAT1 with no external ligand added' 
_pdbx_database_related.db_id          EMD-46948 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              yang.suo@duke.edu 
_pdbx_contact_author.name_first         Seok-Yong 
_pdbx_contact_author.name_last          Lee 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0662-9921 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Suo, Y.'     1 ? 
'Fedor, J.G.' 2 ? 
'Lee, S.-Y.'  3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                5178 
_citation.page_last                 5178 
_citation.title                     'Molecular basis of the urate transporter URAT1 inhibition by gout drugs.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-60480-3 
_citation.pdbx_database_id_PubMed   40467597 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Suo, Y.'     1  0000-0003-1198-7309 
primary 'Fedor, J.G.' 2  0000-0003-3660-3818 
primary 'Zhang, H.'   3  ?                   
primary 'Tsolova, K.' 4  ?                   
primary 'Shi, X.'     5  ?                   
primary 'Sharma, K.'  6  ?                   
primary 'Kumari, S.'  7  ?                   
primary 'Borgnia, M.' 8  0000-0001-9159-1413 
primary 'Zhan, P.'    9  ?                   
primary 'Im, W.'      10 0000-0001-5642-6041 
primary 'Lee, S.Y.'   11 0000-0002-0662-9921 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           URAT1 
_entity.formula_weight             59274.102 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAFSELLDQVGGLGRFQVLQTVALVVPIMWLCTQSMLENFSAAVPSHRCWVPLLDNSTAQASVPGALGPEALLAVSIPPG
PNQGPHQCRRFRQPQWQLLDPNATATNWSEAATEPCVDGWVYDRSTFTSTIVAKWDLVCDSQALKPMAQSIYLAGILVGA
AVCGPASDRFGRRLVLTWSYLQMAVSGTAAAFAPTFPVYCLFRFLVAFAVAGVMMNTGTLVMEWTSAQARPLVMTLNSLG
FSFGHVLMAAVAYGVRDWALLQLVVSVPFFLCFVYSCWLAESARWLLITGRLDRGLRELQRVAAINGKRAVGDTLTPQVL
LSAMQEELSVGQAPASLGTLLRTPGLRLRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQVLIGVVDIPAKIGTLLLL
SRLGRRPTQAASLVLAGLCILANTLVPHEMGALRSALAVLGLGGLGAAFTCITIYSGELFPTVLRMTAVGLGQMAARGGA
ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPAPDTIQDVQNQAVKKATHGTGNPSVLKSTQFSN
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAFSELLDQVGGLGRFQVLQTVALVVPIMWLCTQSMLENFSAAVPSHRCWVPLLDNSTAQASVPGALGPEALLAVSIPPG
PNQGPHQCRRFRQPQWQLLDPNATATNWSEAATEPCVDGWVYDRSTFTSTIVAKWDLVCDSQALKPMAQSIYLAGILVGA
AVCGPASDRFGRRLVLTWSYLQMAVSGTAAAFAPTFPVYCLFRFLVAFAVAGVMMNTGTLVMEWTSAQARPLVMTLNSLG
FSFGHVLMAAVAYGVRDWALLQLVVSVPFFLCFVYSCWLAESARWLLITGRLDRGLRELQRVAAINGKRAVGDTLTPQVL
LSAMQEELSVGQAPASLGTLLRTPGLRLRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQVLIGVVDIPAKIGTLLLL
SRLGRRPTQAASLVLAGLCILANTLVPHEMGALRSALAVLGLGGLGAAFTCITIYSGELFPTVLRMTAVGLGQMAARGGA
ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPAPDTIQDVQNQAVKKATHGTGNPSVLKSTQFSN
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   PHE n 
1 4   SER n 
1 5   GLU n 
1 6   LEU n 
1 7   LEU n 
1 8   ASP n 
1 9   GLN n 
1 10  VAL n 
1 11  GLY n 
1 12  GLY n 
1 13  LEU n 
1 14  GLY n 
1 15  ARG n 
1 16  PHE n 
1 17  GLN n 
1 18  VAL n 
1 19  LEU n 
1 20  GLN n 
1 21  THR n 
1 22  VAL n 
1 23  ALA n 
1 24  LEU n 
1 25  VAL n 
1 26  VAL n 
1 27  PRO n 
1 28  ILE n 
1 29  MET n 
1 30  TRP n 
1 31  LEU n 
1 32  CYS n 
1 33  THR n 
1 34  GLN n 
1 35  SER n 
1 36  MET n 
1 37  LEU n 
1 38  GLU n 
1 39  ASN n 
1 40  PHE n 
1 41  SER n 
1 42  ALA n 
1 43  ALA n 
1 44  VAL n 
1 45  PRO n 
1 46  SER n 
1 47  HIS n 
1 48  ARG n 
1 49  CYS n 
1 50  TRP n 
1 51  VAL n 
1 52  PRO n 
1 53  LEU n 
1 54  LEU n 
1 55  ASP n 
1 56  ASN n 
1 57  SER n 
1 58  THR n 
1 59  ALA n 
1 60  GLN n 
1 61  ALA n 
1 62  SER n 
1 63  VAL n 
1 64  PRO n 
1 65  GLY n 
1 66  ALA n 
1 67  LEU n 
1 68  GLY n 
1 69  PRO n 
1 70  GLU n 
1 71  ALA n 
1 72  LEU n 
1 73  LEU n 
1 74  ALA n 
1 75  VAL n 
1 76  SER n 
1 77  ILE n 
1 78  PRO n 
1 79  PRO n 
1 80  GLY n 
1 81  PRO n 
1 82  ASN n 
1 83  GLN n 
1 84  GLY n 
1 85  PRO n 
1 86  HIS n 
1 87  GLN n 
1 88  CYS n 
1 89  ARG n 
1 90  ARG n 
1 91  PHE n 
1 92  ARG n 
1 93  GLN n 
1 94  PRO n 
1 95  GLN n 
1 96  TRP n 
1 97  GLN n 
1 98  LEU n 
1 99  LEU n 
1 100 ASP n 
1 101 PRO n 
1 102 ASN n 
1 103 ALA n 
1 104 THR n 
1 105 ALA n 
1 106 THR n 
1 107 ASN n 
1 108 TRP n 
1 109 SER n 
1 110 GLU n 
1 111 ALA n 
1 112 ALA n 
1 113 THR n 
1 114 GLU n 
1 115 PRO n 
1 116 CYS n 
1 117 VAL n 
1 118 ASP n 
1 119 GLY n 
1 120 TRP n 
1 121 VAL n 
1 122 TYR n 
1 123 ASP n 
1 124 ARG n 
1 125 SER n 
1 126 THR n 
1 127 PHE n 
1 128 THR n 
1 129 SER n 
1 130 THR n 
1 131 ILE n 
1 132 VAL n 
1 133 ALA n 
1 134 LYS n 
1 135 TRP n 
1 136 ASP n 
1 137 LEU n 
1 138 VAL n 
1 139 CYS n 
1 140 ASP n 
1 141 SER n 
1 142 GLN n 
1 143 ALA n 
1 144 LEU n 
1 145 LYS n 
1 146 PRO n 
1 147 MET n 
1 148 ALA n 
1 149 GLN n 
1 150 SER n 
1 151 ILE n 
1 152 TYR n 
1 153 LEU n 
1 154 ALA n 
1 155 GLY n 
1 156 ILE n 
1 157 LEU n 
1 158 VAL n 
1 159 GLY n 
1 160 ALA n 
1 161 ALA n 
1 162 VAL n 
1 163 CYS n 
1 164 GLY n 
1 165 PRO n 
1 166 ALA n 
1 167 SER n 
1 168 ASP n 
1 169 ARG n 
1 170 PHE n 
1 171 GLY n 
1 172 ARG n 
1 173 ARG n 
1 174 LEU n 
1 175 VAL n 
1 176 LEU n 
1 177 THR n 
1 178 TRP n 
1 179 SER n 
1 180 TYR n 
1 181 LEU n 
1 182 GLN n 
1 183 MET n 
1 184 ALA n 
1 185 VAL n 
1 186 SER n 
1 187 GLY n 
1 188 THR n 
1 189 ALA n 
1 190 ALA n 
1 191 ALA n 
1 192 PHE n 
1 193 ALA n 
1 194 PRO n 
1 195 THR n 
1 196 PHE n 
1 197 PRO n 
1 198 VAL n 
1 199 TYR n 
1 200 CYS n 
1 201 LEU n 
1 202 PHE n 
1 203 ARG n 
1 204 PHE n 
1 205 LEU n 
1 206 VAL n 
1 207 ALA n 
1 208 PHE n 
1 209 ALA n 
1 210 VAL n 
1 211 ALA n 
1 212 GLY n 
1 213 VAL n 
1 214 MET n 
1 215 MET n 
1 216 ASN n 
1 217 THR n 
1 218 GLY n 
1 219 THR n 
1 220 LEU n 
1 221 VAL n 
1 222 MET n 
1 223 GLU n 
1 224 TRP n 
1 225 THR n 
1 226 SER n 
1 227 ALA n 
1 228 GLN n 
1 229 ALA n 
1 230 ARG n 
1 231 PRO n 
1 232 LEU n 
1 233 VAL n 
1 234 MET n 
1 235 THR n 
1 236 LEU n 
1 237 ASN n 
1 238 SER n 
1 239 LEU n 
1 240 GLY n 
1 241 PHE n 
1 242 SER n 
1 243 PHE n 
1 244 GLY n 
1 245 HIS n 
1 246 VAL n 
1 247 LEU n 
1 248 MET n 
1 249 ALA n 
1 250 ALA n 
1 251 VAL n 
1 252 ALA n 
1 253 TYR n 
1 254 GLY n 
1 255 VAL n 
1 256 ARG n 
1 257 ASP n 
1 258 TRP n 
1 259 ALA n 
1 260 LEU n 
1 261 LEU n 
1 262 GLN n 
1 263 LEU n 
1 264 VAL n 
1 265 VAL n 
1 266 SER n 
1 267 VAL n 
1 268 PRO n 
1 269 PHE n 
1 270 PHE n 
1 271 LEU n 
1 272 CYS n 
1 273 PHE n 
1 274 VAL n 
1 275 TYR n 
1 276 SER n 
1 277 CYS n 
1 278 TRP n 
1 279 LEU n 
1 280 ALA n 
1 281 GLU n 
1 282 SER n 
1 283 ALA n 
1 284 ARG n 
1 285 TRP n 
1 286 LEU n 
1 287 LEU n 
1 288 ILE n 
1 289 THR n 
1 290 GLY n 
1 291 ARG n 
1 292 LEU n 
1 293 ASP n 
1 294 ARG n 
1 295 GLY n 
1 296 LEU n 
1 297 ARG n 
1 298 GLU n 
1 299 LEU n 
1 300 GLN n 
1 301 ARG n 
1 302 VAL n 
1 303 ALA n 
1 304 ALA n 
1 305 ILE n 
1 306 ASN n 
1 307 GLY n 
1 308 LYS n 
1 309 ARG n 
1 310 ALA n 
1 311 VAL n 
1 312 GLY n 
1 313 ASP n 
1 314 THR n 
1 315 LEU n 
1 316 THR n 
1 317 PRO n 
1 318 GLN n 
1 319 VAL n 
1 320 LEU n 
1 321 LEU n 
1 322 SER n 
1 323 ALA n 
1 324 MET n 
1 325 GLN n 
1 326 GLU n 
1 327 GLU n 
1 328 LEU n 
1 329 SER n 
1 330 VAL n 
1 331 GLY n 
1 332 GLN n 
1 333 ALA n 
1 334 PRO n 
1 335 ALA n 
1 336 SER n 
1 337 LEU n 
1 338 GLY n 
1 339 THR n 
1 340 LEU n 
1 341 LEU n 
1 342 ARG n 
1 343 THR n 
1 344 PRO n 
1 345 GLY n 
1 346 LEU n 
1 347 ARG n 
1 348 LEU n 
1 349 ARG n 
1 350 THR n 
1 351 CYS n 
1 352 ILE n 
1 353 SER n 
1 354 THR n 
1 355 LEU n 
1 356 CYS n 
1 357 TRP n 
1 358 PHE n 
1 359 ALA n 
1 360 PHE n 
1 361 GLY n 
1 362 PHE n 
1 363 THR n 
1 364 PHE n 
1 365 PHE n 
1 366 GLY n 
1 367 LEU n 
1 368 ALA n 
1 369 LEU n 
1 370 ASP n 
1 371 LEU n 
1 372 GLN n 
1 373 ALA n 
1 374 LEU n 
1 375 GLY n 
1 376 SER n 
1 377 ASN n 
1 378 ILE n 
1 379 PHE n 
1 380 LEU n 
1 381 LEU n 
1 382 GLN n 
1 383 VAL n 
1 384 LEU n 
1 385 ILE n 
1 386 GLY n 
1 387 VAL n 
1 388 VAL n 
1 389 ASP n 
1 390 ILE n 
1 391 PRO n 
1 392 ALA n 
1 393 LYS n 
1 394 ILE n 
1 395 GLY n 
1 396 THR n 
1 397 LEU n 
1 398 LEU n 
1 399 LEU n 
1 400 LEU n 
1 401 SER n 
1 402 ARG n 
1 403 LEU n 
1 404 GLY n 
1 405 ARG n 
1 406 ARG n 
1 407 PRO n 
1 408 THR n 
1 409 GLN n 
1 410 ALA n 
1 411 ALA n 
1 412 SER n 
1 413 LEU n 
1 414 VAL n 
1 415 LEU n 
1 416 ALA n 
1 417 GLY n 
1 418 LEU n 
1 419 CYS n 
1 420 ILE n 
1 421 LEU n 
1 422 ALA n 
1 423 ASN n 
1 424 THR n 
1 425 LEU n 
1 426 VAL n 
1 427 PRO n 
1 428 HIS n 
1 429 GLU n 
1 430 MET n 
1 431 GLY n 
1 432 ALA n 
1 433 LEU n 
1 434 ARG n 
1 435 SER n 
1 436 ALA n 
1 437 LEU n 
1 438 ALA n 
1 439 VAL n 
1 440 LEU n 
1 441 GLY n 
1 442 LEU n 
1 443 GLY n 
1 444 GLY n 
1 445 LEU n 
1 446 GLY n 
1 447 ALA n 
1 448 ALA n 
1 449 PHE n 
1 450 THR n 
1 451 CYS n 
1 452 ILE n 
1 453 THR n 
1 454 ILE n 
1 455 TYR n 
1 456 SER n 
1 457 GLY n 
1 458 GLU n 
1 459 LEU n 
1 460 PHE n 
1 461 PRO n 
1 462 THR n 
1 463 VAL n 
1 464 LEU n 
1 465 ARG n 
1 466 MET n 
1 467 THR n 
1 468 ALA n 
1 469 VAL n 
1 470 GLY n 
1 471 LEU n 
1 472 GLY n 
1 473 GLN n 
1 474 MET n 
1 475 ALA n 
1 476 ALA n 
1 477 ARG n 
1 478 GLY n 
1 479 GLY n 
1 480 ALA n 
1 481 ILE n 
1 482 LEU n 
1 483 GLY n 
1 484 PRO n 
1 485 LEU n 
1 486 VAL n 
1 487 ARG n 
1 488 LEU n 
1 489 LEU n 
1 490 GLY n 
1 491 VAL n 
1 492 HIS n 
1 493 GLY n 
1 494 PRO n 
1 495 TRP n 
1 496 LEU n 
1 497 PRO n 
1 498 LEU n 
1 499 LEU n 
1 500 VAL n 
1 501 TYR n 
1 502 GLY n 
1 503 THR n 
1 504 VAL n 
1 505 PRO n 
1 506 VAL n 
1 507 LEU n 
1 508 SER n 
1 509 GLY n 
1 510 LEU n 
1 511 ALA n 
1 512 ALA n 
1 513 LEU n 
1 514 LEU n 
1 515 LEU n 
1 516 PRO n 
1 517 GLU n 
1 518 THR n 
1 519 GLN n 
1 520 SER n 
1 521 LEU n 
1 522 PRO n 
1 523 ALA n 
1 524 PRO n 
1 525 ASP n 
1 526 THR n 
1 527 ILE n 
1 528 GLN n 
1 529 ASP n 
1 530 VAL n 
1 531 GLN n 
1 532 ASN n 
1 533 GLN n 
1 534 ALA n 
1 535 VAL n 
1 536 LYS n 
1 537 LYS n 
1 538 ALA n 
1 539 THR n 
1 540 HIS n 
1 541 GLY n 
1 542 THR n 
1 543 GLY n 
1 544 ASN n 
1 545 PRO n 
1 546 SER n 
1 547 VAL n 
1 548 LEU n 
1 549 LYS n 
1 550 SER n 
1 551 THR n 
1 552 GLN n 
1 553 PHE n 
1 554 SER n 
1 555 ASN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   555 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   2   ALA ALA A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   SER 4   4   4   SER SER A . n 
A 1 5   GLU 5   5   5   GLU GLU A . n 
A 1 6   LEU 6   6   6   LEU LEU A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   ASP 8   8   8   ASP ASP A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  VAL 10  10  10  VAL VAL A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  GLY 14  14  14  GLY GLY A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  PHE 16  16  16  PHE PHE A . n 
A 1 17  GLN 17  17  17  GLN GLN A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  GLN 20  20  20  GLN GLN A . n 
A 1 21  THR 21  21  21  THR THR A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  VAL 26  26  26  VAL VAL A . n 
A 1 27  PRO 27  27  27  PRO PRO A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  MET 29  29  29  MET MET A . n 
A 1 30  TRP 30  30  30  TRP TRP A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  CYS 32  32  32  CYS CYS A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  GLN 34  34  34  GLN GLN A . n 
A 1 35  SER 35  35  35  SER SER A . n 
A 1 36  MET 36  36  36  MET MET A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  ASN 39  39  39  ASN ASN A . n 
A 1 40  PHE 40  40  40  PHE PHE A . n 
A 1 41  SER 41  41  41  SER SER A . n 
A 1 42  ALA 42  42  42  ALA ALA A . n 
A 1 43  ALA 43  43  43  ALA ALA A . n 
A 1 44  VAL 44  44  44  VAL VAL A . n 
A 1 45  PRO 45  45  45  PRO PRO A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  HIS 47  47  47  HIS HIS A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  CYS 49  49  49  CYS CYS A . n 
A 1 50  TRP 50  50  50  TRP TRP A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  LEU 54  54  54  LEU LEU A . n 
A 1 55  ASP 55  55  55  ASP ASP A . n 
A 1 56  ASN 56  56  56  ASN ASN A . n 
A 1 57  SER 57  57  57  SER SER A . n 
A 1 58  THR 58  58  58  THR THR A . n 
A 1 59  ALA 59  59  59  ALA ALA A . n 
A 1 60  GLN 60  60  60  GLN GLN A . n 
A 1 61  ALA 61  61  61  ALA ALA A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  PRO 64  64  64  PRO PRO A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  ALA 66  66  66  ALA ALA A . n 
A 1 67  LEU 67  67  67  LEU LEU A . n 
A 1 68  GLY 68  68  68  GLY GLY A . n 
A 1 69  PRO 69  69  69  PRO PRO A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  ALA 71  71  71  ALA ALA A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  VAL 75  75  75  VAL VAL A . n 
A 1 76  SER 76  76  76  SER SER A . n 
A 1 77  ILE 77  77  77  ILE ILE A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  PRO 81  81  81  PRO PRO A . n 
A 1 82  ASN 82  82  82  ASN ASN A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  PRO 85  85  85  PRO PRO A . n 
A 1 86  HIS 86  86  86  HIS HIS A . n 
A 1 87  GLN 87  87  87  GLN GLN A . n 
A 1 88  CYS 88  88  88  CYS CYS A . n 
A 1 89  ARG 89  89  89  ARG ARG A . n 
A 1 90  ARG 90  90  90  ARG ARG A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  ARG 92  92  92  ARG ARG A . n 
A 1 93  GLN 93  93  93  GLN GLN A . n 
A 1 94  PRO 94  94  94  PRO PRO A . n 
A 1 95  GLN 95  95  95  GLN GLN A . n 
A 1 96  TRP 96  96  96  TRP TRP A . n 
A 1 97  GLN 97  97  97  GLN GLN A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 ASP 100 100 100 ASP ASP A . n 
A 1 101 PRO 101 101 101 PRO PRO A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 THR 104 104 104 THR THR A . n 
A 1 105 ALA 105 105 105 ALA ALA A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 TRP 108 108 108 TRP TRP A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 GLU 110 110 110 GLU GLU A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 GLU 114 114 114 GLU GLU A . n 
A 1 115 PRO 115 115 115 PRO PRO A . n 
A 1 116 CYS 116 116 116 CYS CYS A . n 
A 1 117 VAL 117 117 117 VAL VAL A . n 
A 1 118 ASP 118 118 118 ASP ASP A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 TRP 120 120 120 TRP TRP A . n 
A 1 121 VAL 121 121 121 VAL VAL A . n 
A 1 122 TYR 122 122 122 TYR TYR A . n 
A 1 123 ASP 123 123 123 ASP ASP A . n 
A 1 124 ARG 124 124 124 ARG ARG A . n 
A 1 125 SER 125 125 125 SER SER A . n 
A 1 126 THR 126 126 126 THR THR A . n 
A 1 127 PHE 127 127 127 PHE PHE A . n 
A 1 128 THR 128 128 128 THR THR A . n 
A 1 129 SER 129 129 129 SER SER A . n 
A 1 130 THR 130 130 130 THR THR A . n 
A 1 131 ILE 131 131 131 ILE ILE A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 LYS 134 134 134 LYS LYS A . n 
A 1 135 TRP 135 135 135 TRP TRP A . n 
A 1 136 ASP 136 136 136 ASP ASP A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 VAL 138 138 138 VAL VAL A . n 
A 1 139 CYS 139 139 139 CYS CYS A . n 
A 1 140 ASP 140 140 140 ASP ASP A . n 
A 1 141 SER 141 141 141 SER SER A . n 
A 1 142 GLN 142 142 142 GLN GLN A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 LYS 145 145 145 LYS LYS A . n 
A 1 146 PRO 146 146 146 PRO PRO A . n 
A 1 147 MET 147 147 147 MET MET A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 GLN 149 149 149 GLN GLN A . n 
A 1 150 SER 150 150 150 SER SER A . n 
A 1 151 ILE 151 151 151 ILE ILE A . n 
A 1 152 TYR 152 152 152 TYR TYR A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 ILE 156 156 156 ILE ILE A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 VAL 158 158 158 VAL VAL A . n 
A 1 159 GLY 159 159 159 GLY GLY A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 VAL 162 162 162 VAL VAL A . n 
A 1 163 CYS 163 163 163 CYS CYS A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 PRO 165 165 165 PRO PRO A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 SER 167 167 167 SER SER A . n 
A 1 168 ASP 168 168 168 ASP ASP A . n 
A 1 169 ARG 169 169 169 ARG ARG A . n 
A 1 170 PHE 170 170 170 PHE PHE A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 ARG 172 172 172 ARG ARG A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 LEU 174 174 174 LEU LEU A . n 
A 1 175 VAL 175 175 175 VAL VAL A . n 
A 1 176 LEU 176 176 176 LEU LEU A . n 
A 1 177 THR 177 177 177 THR THR A . n 
A 1 178 TRP 178 178 178 TRP TRP A . n 
A 1 179 SER 179 179 179 SER SER A . n 
A 1 180 TYR 180 180 180 TYR TYR A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 GLN 182 182 182 GLN GLN A . n 
A 1 183 MET 183 183 183 MET MET A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 SER 186 186 186 SER SER A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 THR 188 188 188 THR THR A . n 
A 1 189 ALA 189 189 189 ALA ALA A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 PHE 192 192 192 PHE PHE A . n 
A 1 193 ALA 193 193 193 ALA ALA A . n 
A 1 194 PRO 194 194 194 PRO PRO A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 PRO 197 197 197 PRO PRO A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 TYR 199 199 199 TYR TYR A . n 
A 1 200 CYS 200 200 200 CYS CYS A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 PHE 202 202 202 PHE PHE A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 PHE 204 204 204 PHE PHE A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 ALA 207 207 207 ALA ALA A . n 
A 1 208 PHE 208 208 208 PHE PHE A . n 
A 1 209 ALA 209 209 209 ALA ALA A . n 
A 1 210 VAL 210 210 210 VAL VAL A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 GLY 212 212 212 GLY GLY A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 MET 214 214 214 MET MET A . n 
A 1 215 MET 215 215 215 MET MET A . n 
A 1 216 ASN 216 216 216 ASN ASN A . n 
A 1 217 THR 217 217 217 THR THR A . n 
A 1 218 GLY 218 218 218 GLY GLY A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 MET 222 222 222 MET MET A . n 
A 1 223 GLU 223 223 223 GLU GLU A . n 
A 1 224 TRP 224 224 224 TRP TRP A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 SER 226 226 226 SER SER A . n 
A 1 227 ALA 227 227 227 ALA ALA A . n 
A 1 228 GLN 228 228 228 GLN GLN A . n 
A 1 229 ALA 229 229 229 ALA ALA A . n 
A 1 230 ARG 230 230 230 ARG ARG A . n 
A 1 231 PRO 231 231 231 PRO PRO A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 MET 234 234 234 MET MET A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 ASN 237 237 237 ASN ASN A . n 
A 1 238 SER 238 238 238 SER SER A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLY 240 240 240 GLY GLY A . n 
A 1 241 PHE 241 241 241 PHE PHE A . n 
A 1 242 SER 242 242 242 SER SER A . n 
A 1 243 PHE 243 243 243 PHE PHE A . n 
A 1 244 GLY 244 244 244 GLY GLY A . n 
A 1 245 HIS 245 245 245 HIS HIS A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 MET 248 248 248 MET MET A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 TYR 253 253 253 TYR TYR A . n 
A 1 254 GLY 254 254 254 GLY GLY A . n 
A 1 255 VAL 255 255 255 VAL VAL A . n 
A 1 256 ARG 256 256 256 ARG ARG A . n 
A 1 257 ASP 257 257 257 ASP ASP A . n 
A 1 258 TRP 258 258 258 TRP TRP A . n 
A 1 259 ALA 259 259 259 ALA ALA A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 GLN 262 262 262 GLN GLN A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 VAL 264 264 264 VAL VAL A . n 
A 1 265 VAL 265 265 265 VAL VAL A . n 
A 1 266 SER 266 266 266 SER SER A . n 
A 1 267 VAL 267 267 267 VAL VAL A . n 
A 1 268 PRO 268 268 268 PRO PRO A . n 
A 1 269 PHE 269 269 269 PHE PHE A . n 
A 1 270 PHE 270 270 270 PHE PHE A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 CYS 272 272 272 CYS CYS A . n 
A 1 273 PHE 273 273 273 PHE PHE A . n 
A 1 274 VAL 274 274 274 VAL VAL A . n 
A 1 275 TYR 275 275 275 TYR TYR A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 CYS 277 277 277 CYS CYS A . n 
A 1 278 TRP 278 278 278 TRP TRP A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 ALA 280 280 280 ALA ALA A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 SER 282 282 282 SER SER A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 ARG 284 284 284 ARG ARG A . n 
A 1 285 TRP 285 285 285 TRP TRP A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 THR 289 289 289 THR THR A . n 
A 1 290 GLY 290 290 290 GLY GLY A . n 
A 1 291 ARG 291 291 291 ARG ARG A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 ASP 293 293 293 ASP ASP A . n 
A 1 294 ARG 294 294 294 ARG ARG A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 ARG 297 297 297 ARG ARG A . n 
A 1 298 GLU 298 298 298 GLU GLU A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 GLN 300 300 300 GLN GLN A . n 
A 1 301 ARG 301 301 301 ARG ARG A . n 
A 1 302 VAL 302 302 302 VAL VAL A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 ALA 304 304 304 ALA ALA A . n 
A 1 305 ILE 305 305 305 ILE ILE A . n 
A 1 306 ASN 306 306 306 ASN ASN A . n 
A 1 307 GLY 307 307 307 GLY GLY A . n 
A 1 308 LYS 308 308 308 LYS LYS A . n 
A 1 309 ARG 309 309 309 ARG ARG A . n 
A 1 310 ALA 310 310 310 ALA ALA A . n 
A 1 311 VAL 311 311 311 VAL VAL A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 ASP 313 313 313 ASP ASP A . n 
A 1 314 THR 314 314 314 THR THR A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 THR 316 316 316 THR THR A . n 
A 1 317 PRO 317 317 317 PRO PRO A . n 
A 1 318 GLN 318 318 318 GLN GLN A . n 
A 1 319 VAL 319 319 319 VAL VAL A . n 
A 1 320 LEU 320 320 320 LEU LEU A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 ALA 323 323 323 ALA ALA A . n 
A 1 324 MET 324 324 324 MET MET A . n 
A 1 325 GLN 325 325 325 GLN GLN A . n 
A 1 326 GLU 326 326 326 GLU GLU A . n 
A 1 327 GLU 327 327 327 GLU GLU A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 SER 329 329 329 SER SER A . n 
A 1 330 VAL 330 330 330 VAL VAL A . n 
A 1 331 GLY 331 331 331 GLY GLY A . n 
A 1 332 GLN 332 332 332 GLN GLN A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 ALA 335 335 335 ALA ALA A . n 
A 1 336 SER 336 336 336 SER SER A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 GLY 338 338 338 GLY GLY A . n 
A 1 339 THR 339 339 339 THR THR A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 ARG 342 342 342 ARG ARG A . n 
A 1 343 THR 343 343 343 THR THR A . n 
A 1 344 PRO 344 344 344 PRO PRO A . n 
A 1 345 GLY 345 345 345 GLY GLY A . n 
A 1 346 LEU 346 346 346 LEU LEU A . n 
A 1 347 ARG 347 347 347 ARG ARG A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 ARG 349 349 349 ARG ARG A . n 
A 1 350 THR 350 350 350 THR THR A . n 
A 1 351 CYS 351 351 351 CYS CYS A . n 
A 1 352 ILE 352 352 352 ILE ILE A . n 
A 1 353 SER 353 353 353 SER SER A . n 
A 1 354 THR 354 354 354 THR THR A . n 
A 1 355 LEU 355 355 355 LEU LEU A . n 
A 1 356 CYS 356 356 356 CYS CYS A . n 
A 1 357 TRP 357 357 357 TRP TRP A . n 
A 1 358 PHE 358 358 358 PHE PHE A . n 
A 1 359 ALA 359 359 359 ALA ALA A . n 
A 1 360 PHE 360 360 360 PHE PHE A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 THR 363 363 363 THR THR A . n 
A 1 364 PHE 364 364 364 PHE PHE A . n 
A 1 365 PHE 365 365 365 PHE PHE A . n 
A 1 366 GLY 366 366 366 GLY GLY A . n 
A 1 367 LEU 367 367 367 LEU LEU A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 ASP 370 370 370 ASP ASP A . n 
A 1 371 LEU 371 371 371 LEU LEU A . n 
A 1 372 GLN 372 372 372 GLN GLN A . n 
A 1 373 ALA 373 373 373 ALA ALA A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 GLY 375 375 375 GLY GLY A . n 
A 1 376 SER 376 376 376 SER SER A . n 
A 1 377 ASN 377 377 377 ASN ASN A . n 
A 1 378 ILE 378 378 378 ILE ILE A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 LEU 380 380 380 LEU LEU A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 GLN 382 382 382 GLN GLN A . n 
A 1 383 VAL 383 383 383 VAL VAL A . n 
A 1 384 LEU 384 384 384 LEU LEU A . n 
A 1 385 ILE 385 385 385 ILE ILE A . n 
A 1 386 GLY 386 386 386 GLY GLY A . n 
A 1 387 VAL 387 387 387 VAL VAL A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 ASP 389 389 389 ASP ASP A . n 
A 1 390 ILE 390 390 390 ILE ILE A . n 
A 1 391 PRO 391 391 391 PRO PRO A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 LYS 393 393 393 LYS LYS A . n 
A 1 394 ILE 394 394 394 ILE ILE A . n 
A 1 395 GLY 395 395 395 GLY GLY A . n 
A 1 396 THR 396 396 396 THR THR A . n 
A 1 397 LEU 397 397 397 LEU LEU A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 LEU 399 399 399 LEU LEU A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 SER 401 401 401 SER SER A . n 
A 1 402 ARG 402 402 402 ARG ARG A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 GLY 404 404 404 GLY GLY A . n 
A 1 405 ARG 405 405 405 ARG ARG A . n 
A 1 406 ARG 406 406 406 ARG ARG A . n 
A 1 407 PRO 407 407 407 PRO PRO A . n 
A 1 408 THR 408 408 408 THR THR A . n 
A 1 409 GLN 409 409 409 GLN GLN A . n 
A 1 410 ALA 410 410 410 ALA ALA A . n 
A 1 411 ALA 411 411 411 ALA ALA A . n 
A 1 412 SER 412 412 412 SER SER A . n 
A 1 413 LEU 413 413 413 LEU LEU A . n 
A 1 414 VAL 414 414 414 VAL VAL A . n 
A 1 415 LEU 415 415 415 LEU LEU A . n 
A 1 416 ALA 416 416 416 ALA ALA A . n 
A 1 417 GLY 417 417 417 GLY GLY A . n 
A 1 418 LEU 418 418 418 LEU LEU A . n 
A 1 419 CYS 419 419 419 CYS CYS A . n 
A 1 420 ILE 420 420 420 ILE ILE A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 ALA 422 422 422 ALA ALA A . n 
A 1 423 ASN 423 423 423 ASN ASN A . n 
A 1 424 THR 424 424 424 THR THR A . n 
A 1 425 LEU 425 425 425 LEU LEU A . n 
A 1 426 VAL 426 426 426 VAL VAL A . n 
A 1 427 PRO 427 427 427 PRO PRO A . n 
A 1 428 HIS 428 428 428 HIS HIS A . n 
A 1 429 GLU 429 429 429 GLU GLU A . n 
A 1 430 MET 430 430 430 MET MET A . n 
A 1 431 GLY 431 431 431 GLY GLY A . n 
A 1 432 ALA 432 432 432 ALA ALA A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 ARG 434 434 434 ARG ARG A . n 
A 1 435 SER 435 435 435 SER SER A . n 
A 1 436 ALA 436 436 436 ALA ALA A . n 
A 1 437 LEU 437 437 437 LEU LEU A . n 
A 1 438 ALA 438 438 438 ALA ALA A . n 
A 1 439 VAL 439 439 439 VAL VAL A . n 
A 1 440 LEU 440 440 440 LEU LEU A . n 
A 1 441 GLY 441 441 441 GLY GLY A . n 
A 1 442 LEU 442 442 442 LEU LEU A . n 
A 1 443 GLY 443 443 443 GLY GLY A . n 
A 1 444 GLY 444 444 444 GLY GLY A . n 
A 1 445 LEU 445 445 445 LEU LEU A . n 
A 1 446 GLY 446 446 446 GLY GLY A . n 
A 1 447 ALA 447 447 447 ALA ALA A . n 
A 1 448 ALA 448 448 448 ALA ALA A . n 
A 1 449 PHE 449 449 449 PHE PHE A . n 
A 1 450 THR 450 450 450 THR THR A . n 
A 1 451 CYS 451 451 451 CYS CYS A . n 
A 1 452 ILE 452 452 452 ILE ILE A . n 
A 1 453 THR 453 453 453 THR THR A . n 
A 1 454 ILE 454 454 454 ILE ILE A . n 
A 1 455 TYR 455 455 455 TYR TYR A . n 
A 1 456 SER 456 456 456 SER SER A . n 
A 1 457 GLY 457 457 457 GLY GLY A . n 
A 1 458 GLU 458 458 458 GLU GLU A . n 
A 1 459 LEU 459 459 459 LEU LEU A . n 
A 1 460 PHE 460 460 460 PHE PHE A . n 
A 1 461 PRO 461 461 461 PRO PRO A . n 
A 1 462 THR 462 462 462 THR THR A . n 
A 1 463 VAL 463 463 463 VAL VAL A . n 
A 1 464 LEU 464 464 464 LEU LEU A . n 
A 1 465 ARG 465 465 465 ARG ARG A . n 
A 1 466 MET 466 466 466 MET MET A . n 
A 1 467 THR 467 467 467 THR THR A . n 
A 1 468 ALA 468 468 468 ALA ALA A . n 
A 1 469 VAL 469 469 469 VAL VAL A . n 
A 1 470 GLY 470 470 470 GLY GLY A . n 
A 1 471 LEU 471 471 471 LEU LEU A . n 
A 1 472 GLY 472 472 472 GLY GLY A . n 
A 1 473 GLN 473 473 473 GLN GLN A . n 
A 1 474 MET 474 474 474 MET MET A . n 
A 1 475 ALA 475 475 475 ALA ALA A . n 
A 1 476 ALA 476 476 476 ALA ALA A . n 
A 1 477 ARG 477 477 477 ARG ARG A . n 
A 1 478 GLY 478 478 478 GLY GLY A . n 
A 1 479 GLY 479 479 479 GLY GLY A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 ILE 481 481 481 ILE ILE A . n 
A 1 482 LEU 482 482 482 LEU LEU A . n 
A 1 483 GLY 483 483 483 GLY GLY A . n 
A 1 484 PRO 484 484 484 PRO PRO A . n 
A 1 485 LEU 485 485 485 LEU LEU A . n 
A 1 486 VAL 486 486 486 VAL VAL A . n 
A 1 487 ARG 487 487 487 ARG ARG A . n 
A 1 488 LEU 488 488 488 LEU LEU A . n 
A 1 489 LEU 489 489 489 LEU LEU A . n 
A 1 490 GLY 490 490 490 GLY GLY A . n 
A 1 491 VAL 491 491 491 VAL VAL A . n 
A 1 492 HIS 492 492 492 HIS HIS A . n 
A 1 493 GLY 493 493 493 GLY GLY A . n 
A 1 494 PRO 494 494 494 PRO PRO A . n 
A 1 495 TRP 495 495 495 TRP TRP A . n 
A 1 496 LEU 496 496 496 LEU LEU A . n 
A 1 497 PRO 497 497 497 PRO PRO A . n 
A 1 498 LEU 498 498 498 LEU LEU A . n 
A 1 499 LEU 499 499 499 LEU LEU A . n 
A 1 500 VAL 500 500 500 VAL VAL A . n 
A 1 501 TYR 501 501 501 TYR TYR A . n 
A 1 502 GLY 502 502 502 GLY GLY A . n 
A 1 503 THR 503 503 503 THR THR A . n 
A 1 504 VAL 504 504 504 VAL VAL A . n 
A 1 505 PRO 505 505 505 PRO PRO A . n 
A 1 506 VAL 506 506 506 VAL VAL A . n 
A 1 507 LEU 507 507 507 LEU LEU A . n 
A 1 508 SER 508 508 508 SER SER A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 LEU 510 510 510 LEU LEU A . n 
A 1 511 ALA 511 511 511 ALA ALA A . n 
A 1 512 ALA 512 512 512 ALA ALA A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 LEU 514 514 514 LEU LEU A . n 
A 1 515 LEU 515 515 515 LEU LEU A . n 
A 1 516 PRO 516 516 516 PRO PRO A . n 
A 1 517 GLU 517 517 517 GLU GLU A . n 
A 1 518 THR 518 518 518 THR THR A . n 
A 1 519 GLN 519 519 ?   ?   ?   A . n 
A 1 520 SER 520 520 ?   ?   ?   A . n 
A 1 521 LEU 521 521 ?   ?   ?   A . n 
A 1 522 PRO 522 522 ?   ?   ?   A . n 
A 1 523 ALA 523 523 ?   ?   ?   A . n 
A 1 524 PRO 524 524 ?   ?   ?   A . n 
A 1 525 ASP 525 525 ?   ?   ?   A . n 
A 1 526 THR 526 526 ?   ?   ?   A . n 
A 1 527 ILE 527 527 ?   ?   ?   A . n 
A 1 528 GLN 528 528 ?   ?   ?   A . n 
A 1 529 ASP 529 529 ?   ?   ?   A . n 
A 1 530 VAL 530 530 ?   ?   ?   A . n 
A 1 531 GLN 531 531 ?   ?   ?   A . n 
A 1 532 ASN 532 532 ?   ?   ?   A . n 
A 1 533 GLN 533 533 ?   ?   ?   A . n 
A 1 534 ALA 534 534 ?   ?   ?   A . n 
A 1 535 VAL 535 535 ?   ?   ?   A . n 
A 1 536 LYS 536 536 ?   ?   ?   A . n 
A 1 537 LYS 537 537 ?   ?   ?   A . n 
A 1 538 ALA 538 538 ?   ?   ?   A . n 
A 1 539 THR 539 539 ?   ?   ?   A . n 
A 1 540 HIS 540 540 ?   ?   ?   A . n 
A 1 541 GLY 541 541 ?   ?   ?   A . n 
A 1 542 THR 542 542 ?   ?   ?   A . n 
A 1 543 GLY 543 543 ?   ?   ?   A . n 
A 1 544 ASN 544 544 ?   ?   ?   A . n 
A 1 545 PRO 545 545 ?   ?   ?   A . n 
A 1 546 SER 546 546 ?   ?   ?   A . n 
A 1 547 VAL 547 547 ?   ?   ?   A . n 
A 1 548 LEU 548 548 ?   ?   ?   A . n 
A 1 549 LYS 549 549 ?   ?   ?   A . n 
A 1 550 SER 550 550 ?   ?   ?   A . n 
A 1 551 THR 551 551 ?   ?   ?   A . n 
A 1 552 GLN 552 552 ?   ?   ?   A . n 
A 1 553 PHE 553 553 ?   ?   ?   A . n 
A 1 554 SER 554 554 ?   ?   ?   A . n 
A 1 555 ASN 555 555 ?   ?   ?   A . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LEU 31  ? CG  ? A LEU 31  CG  
2  1 Y 1 A LEU 31  ? CD1 ? A LEU 31  CD1 
3  1 Y 1 A LEU 31  ? CD2 ? A LEU 31  CD2 
4  1 Y 1 A SER 57  ? OG  ? A SER 57  OG  
5  1 Y 1 A THR 58  ? OG1 ? A THR 58  OG1 
6  1 Y 1 A THR 58  ? CG2 ? A THR 58  CG2 
7  1 Y 1 A GLN 60  ? CG  ? A GLN 60  CG  
8  1 Y 1 A GLN 60  ? CD  ? A GLN 60  CD  
9  1 Y 1 A GLN 60  ? OE1 ? A GLN 60  OE1 
10 1 Y 1 A GLN 60  ? NE2 ? A GLN 60  NE2 
11 1 Y 1 A SER 62  ? OG  ? A SER 62  OG  
12 1 Y 1 A VAL 63  ? CG1 ? A VAL 63  CG1 
13 1 Y 1 A VAL 63  ? CG2 ? A VAL 63  CG2 
14 1 Y 1 A PRO 64  ? CG  ? A PRO 64  CG  
15 1 Y 1 A PRO 64  ? CD  ? A PRO 64  CD  
16 1 Y 1 A LEU 67  ? CG  ? A LEU 67  CG  
17 1 Y 1 A LEU 67  ? CD1 ? A LEU 67  CD1 
18 1 Y 1 A LEU 67  ? CD2 ? A LEU 67  CD2 
19 1 Y 1 A LEU 98  ? CG  ? A LEU 98  CG  
20 1 Y 1 A LEU 98  ? CD1 ? A LEU 98  CD1 
21 1 Y 1 A LEU 98  ? CD2 ? A LEU 98  CD2 
22 1 Y 1 A LEU 99  ? CG  ? A LEU 99  CG  
23 1 Y 1 A LEU 99  ? CD1 ? A LEU 99  CD1 
24 1 Y 1 A LEU 99  ? CD2 ? A LEU 99  CD2 
25 1 Y 1 A ASP 100 ? CG  ? A ASP 100 CG  
26 1 Y 1 A ASP 100 ? OD1 ? A ASP 100 OD1 
27 1 Y 1 A ASP 100 ? OD2 ? A ASP 100 OD2 
28 1 Y 1 A PRO 101 ? CG  ? A PRO 101 CG  
29 1 Y 1 A PRO 101 ? CD  ? A PRO 101 CD  
30 1 Y 1 A ASN 102 ? CG  ? A ASN 102 CG  
31 1 Y 1 A ASN 102 ? OD1 ? A ASN 102 OD1 
32 1 Y 1 A ASN 102 ? ND2 ? A ASN 102 ND2 
33 1 Y 1 A THR 104 ? OG1 ? A THR 104 OG1 
34 1 Y 1 A THR 104 ? CG2 ? A THR 104 CG2 
35 1 Y 1 A THR 106 ? OG1 ? A THR 106 OG1 
36 1 Y 1 A THR 106 ? CG2 ? A THR 106 CG2 
37 1 Y 1 A ASN 107 ? CG  ? A ASN 107 CG  
38 1 Y 1 A ASN 107 ? OD1 ? A ASN 107 OD1 
39 1 Y 1 A ASN 107 ? ND2 ? A ASN 107 ND2 
40 1 Y 1 A TRP 108 ? CG  ? A TRP 108 CG  
41 1 Y 1 A TRP 108 ? CD1 ? A TRP 108 CD1 
42 1 Y 1 A TRP 108 ? CD2 ? A TRP 108 CD2 
43 1 Y 1 A TRP 108 ? NE1 ? A TRP 108 NE1 
44 1 Y 1 A TRP 108 ? CE2 ? A TRP 108 CE2 
45 1 Y 1 A TRP 108 ? CE3 ? A TRP 108 CE3 
46 1 Y 1 A TRP 108 ? CZ2 ? A TRP 108 CZ2 
47 1 Y 1 A TRP 108 ? CZ3 ? A TRP 108 CZ3 
48 1 Y 1 A TRP 108 ? CH2 ? A TRP 108 CH2 
49 1 Y 1 A SER 109 ? OG  ? A SER 109 OG  
50 1 Y 1 A GLU 110 ? CG  ? A GLU 110 CG  
51 1 Y 1 A GLU 110 ? CD  ? A GLU 110 CD  
52 1 Y 1 A GLU 110 ? OE1 ? A GLU 110 OE1 
53 1 Y 1 A GLU 110 ? OE2 ? A GLU 110 OE2 
54 1 Y 1 A THR 113 ? OG1 ? A THR 113 OG1 
55 1 Y 1 A THR 113 ? CG2 ? A THR 113 CG2 
56 1 Y 1 A LEU 321 ? CG  ? A LEU 321 CG  
57 1 Y 1 A LEU 321 ? CD1 ? A LEU 321 CD1 
58 1 Y 1 A LEU 321 ? CD2 ? A LEU 321 CD2 
59 1 Y 1 A LEU 328 ? CG  ? A LEU 328 CG  
60 1 Y 1 A LEU 328 ? CD1 ? A LEU 328 CD1 
61 1 Y 1 A LEU 328 ? CD2 ? A LEU 328 CD2 
62 1 Y 1 A VAL 330 ? CG1 ? A VAL 330 CG1 
63 1 Y 1 A VAL 330 ? CG2 ? A VAL 330 CG2 
64 1 Y 1 A SER 336 ? OG  ? A SER 336 OG  
65 1 Y 1 A LEU 464 ? CG  ? A LEU 464 CG  
66 1 Y 1 A LEU 464 ? CD1 ? A LEU 464 CD1 
67 1 Y 1 A LEU 464 ? CD2 ? A LEU 464 CD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DK9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DK9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DK9 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9DK9 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_Zscore 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 3904 ? f_bond_d           ? ? ? 
'ELECTRON MICROSCOPY' ? 0.551 ? 5337 ? f_angle_d          ? ? ? 
'ELECTRON MICROSCOPY' ? 3.670 ? 553  ? f_dihedral_angle_d ? ? ? 
'ELECTRON MICROSCOPY' ? 0.035 ? 638  ? f_chiral_restr     ? ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 675  ? f_plane_restr      ? ? ? 
# 
_struct.entry_id                     9DK9 
_struct.title                        'Structure of URAT1 with no external ligand added' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DK9 
_struct_keywords.text            'Membrane protein, membrane transporter, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9DK9 
_struct_ref.pdbx_db_accession          9DK9 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9DK9 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 555 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             9DK9 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  555 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       555 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PHE A 3   ? GLY A 11  ? PHE A 3   GLY A 11  1 ? 9  
HELX_P HELX_P2  AA2 GLY A 14  ? LEU A 37  ? GLY A 14  LEU A 37  1 ? 24 
HELX_P HELX_P3  AA3 LEU A 37  ? ALA A 42  ? LEU A 37  ALA A 42  1 ? 6  
HELX_P HELX_P4  AA4 VAL A 51  ? ASN A 56  ? VAL A 51  ASN A 56  1 ? 6  
HELX_P HELX_P5  AA5 ASN A 56  ? VAL A 63  ? ASN A 56  VAL A 63  1 ? 8  
HELX_P HELX_P6  AA6 GLY A 68  ? VAL A 75  ? GLY A 68  VAL A 75  1 ? 8  
HELX_P HELX_P7  AA7 GLN A 95  ? ASP A 100 ? GLN A 95  ASP A 100 5 ? 6  
HELX_P HELX_P8  AA8 SER A 109 ? ALA A 111 ? SER A 109 ALA A 111 5 ? 3  
HELX_P HELX_P9  AA9 THR A 130 ? ASP A 136 ? THR A 130 ASP A 136 1 ? 7  
HELX_P HELX_P10 AB1 VAL A 138 ? GLN A 142 ? VAL A 138 GLN A 142 5 ? 5  
HELX_P HELX_P11 AB2 ALA A 143 ? ASP A 168 ? ALA A 143 ASP A 168 1 ? 26 
HELX_P HELX_P12 AB3 ARG A 172 ? ALA A 191 ? ARG A 172 ALA A 191 1 ? 20 
HELX_P HELX_P13 AB4 THR A 195 ? THR A 225 ? THR A 195 THR A 225 1 ? 31 
HELX_P HELX_P14 AB5 SER A 226 ? GLN A 228 ? SER A 226 GLN A 228 5 ? 3  
HELX_P HELX_P15 AB6 ALA A 229 ? TYR A 253 ? ALA A 229 TYR A 253 1 ? 25 
HELX_P HELX_P16 AB7 ALA A 259 ? VAL A 267 ? ALA A 259 VAL A 267 1 ? 9  
HELX_P HELX_P17 AB8 VAL A 267 ? SER A 276 ? VAL A 267 SER A 276 1 ? 10 
HELX_P HELX_P18 AB9 SER A 282 ? THR A 289 ? SER A 282 THR A 289 1 ? 8  
HELX_P HELX_P19 AC1 LEU A 292 ? GLY A 307 ? LEU A 292 GLY A 307 1 ? 16 
HELX_P HELX_P20 AC2 LYS A 308 ? LEU A 315 ? LYS A 308 LEU A 315 1 ? 8  
HELX_P HELX_P21 AC3 THR A 316 ? MET A 324 ? THR A 316 MET A 324 1 ? 9  
HELX_P HELX_P22 AC4 MET A 324 ? VAL A 330 ? MET A 324 VAL A 330 1 ? 7  
HELX_P HELX_P23 AC5 SER A 336 ? LEU A 340 ? SER A 336 LEU A 340 5 ? 5  
HELX_P HELX_P24 AC6 THR A 343 ? GLY A 345 ? THR A 343 GLY A 345 5 ? 3  
HELX_P HELX_P25 AC7 LEU A 346 ? ASP A 370 ? LEU A 346 ASP A 370 1 ? 25 
HELX_P HELX_P26 AC8 ASP A 370 ? GLY A 375 ? ASP A 370 GLY A 375 1 ? 6  
HELX_P HELX_P27 AC9 ASN A 377 ? LEU A 403 ? ASN A 377 LEU A 403 1 ? 27 
HELX_P HELX_P28 AD1 GLY A 404 ? VAL A 426 ? GLY A 404 VAL A 426 1 ? 23 
HELX_P HELX_P29 AD2 MET A 430 ? PHE A 460 ? MET A 430 PHE A 460 1 ? 31 
HELX_P HELX_P30 AD3 LEU A 464 ? VAL A 486 ? LEU A 464 VAL A 486 1 ? 23 
HELX_P HELX_P31 AD4 ARG A 487 ? HIS A 492 ? ARG A 487 HIS A 492 5 ? 6  
HELX_P HELX_P32 AD5 PRO A 494 ? ALA A 512 ? PRO A 494 ALA A 512 1 ? 19 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 49 SG ? ? ? 1_555 A CYS 116 SG ? ? A CYS 49 A CYS 116 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ? ? A CYS 88 SG ? ? ? 1_555 A CYS 139 SG ? ? A CYS 88 A CYS 139 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 49 ? CYS A 116 ? CYS A 49 ? 1_555 CYS A 116 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 88 ? CYS A 139 ? CYS A 88 ? 1_555 CYS A 139 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 48  ? CYS A 49  ? ARG A 48  CYS A 49  
AA1 2 TRP A 120 ? VAL A 121 ? TRP A 120 VAL A 121 
AA2 1 PRO A 79  ? GLY A 80  ? PRO A 79  GLY A 80  
AA2 2 GLY A 84  ? PRO A 85  ? GLY A 84  PRO A 85  
AA3 1 ARG A 90  ? PHE A 91  ? ARG A 90  PHE A 91  
AA3 2 THR A 113 ? GLU A 114 ? THR A 113 GLU A 114 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG A 48 ? N ARG A 48 O VAL A 121 ? O VAL A 121 
AA2 1 2 N GLY A 80 ? N GLY A 80 O GLY A 84  ? O GLY A 84  
AA3 1 2 N ARG A 90 ? N ARG A 90 O GLU A 114 ? O GLU A 114 
# 
_pdbx_entry_details.entry_id                   9DK9 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 139 ? ? 57.74  -110.66 
2 1 ASP A 370 ? ? -96.63 58.00   
3 1 PRO A 461 ? ? -59.74 171.90  
4 1 ALA A 512 ? ? -69.03 4.04    
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9DK9 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   200 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  8ET6 
_em_3d_fitting_list.pdb_chain_id                  A 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      A 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                8ET6 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9DK9 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'FOURIER SPACE' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.68 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               527705 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          1 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 URAT1 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                9DK9 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4092 
_em_image_scans.dimension_width         5760 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9DK9 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   70 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            100 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
_em_imaging.objective_aperture              ? 
_em_imaging.microscope_serial_number        ? 
_em_imaging.microscope_version              ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9DK9 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   280 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9DK9 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9DK9 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A GLN 519 ? A GLN 519 
3  1 Y 1 A SER 520 ? A SER 520 
4  1 Y 1 A LEU 521 ? A LEU 521 
5  1 Y 1 A PRO 522 ? A PRO 522 
6  1 Y 1 A ALA 523 ? A ALA 523 
7  1 Y 1 A PRO 524 ? A PRO 524 
8  1 Y 1 A ASP 525 ? A ASP 525 
9  1 Y 1 A THR 526 ? A THR 526 
10 1 Y 1 A ILE 527 ? A ILE 527 
11 1 Y 1 A GLN 528 ? A GLN 528 
12 1 Y 1 A ASP 529 ? A ASP 529 
13 1 Y 1 A VAL 530 ? A VAL 530 
14 1 Y 1 A GLN 531 ? A GLN 531 
15 1 Y 1 A ASN 532 ? A ASN 532 
16 1 Y 1 A GLN 533 ? A GLN 533 
17 1 Y 1 A ALA 534 ? A ALA 534 
18 1 Y 1 A VAL 535 ? A VAL 535 
19 1 Y 1 A LYS 536 ? A LYS 536 
20 1 Y 1 A LYS 537 ? A LYS 537 
21 1 Y 1 A ALA 538 ? A ALA 538 
22 1 Y 1 A THR 539 ? A THR 539 
23 1 Y 1 A HIS 540 ? A HIS 540 
24 1 Y 1 A GLY 541 ? A GLY 541 
25 1 Y 1 A THR 542 ? A THR 542 
26 1 Y 1 A GLY 543 ? A GLY 543 
27 1 Y 1 A ASN 544 ? A ASN 544 
28 1 Y 1 A PRO 545 ? A PRO 545 
29 1 Y 1 A SER 546 ? A SER 546 
30 1 Y 1 A VAL 547 ? A VAL 547 
31 1 Y 1 A LEU 548 ? A LEU 548 
32 1 Y 1 A LYS 549 ? A LYS 549 
33 1 Y 1 A SER 550 ? A SER 550 
34 1 Y 1 A THR 551 ? A THR 551 
35 1 Y 1 A GLN 552 ? A GLN 552 
36 1 Y 1 A PHE 553 ? A PHE 553 
37 1 Y 1 A SER 554 ? A SER 554 
38 1 Y 1 A ASN 555 ? A ASN 555 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-08 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9DK9 
_em_admin.last_update        2025-06-18 
_em_admin.map_release_date   2025-06-18 
_em_admin.title              'Structure of URAT1 with no external ligand added' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20    mM Tris 1 Tris 
1 150   mM NaCl 2 NaCl 
1 0.005 %  LMNG 3 LMNG 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.055 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               1.8 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     18880 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   6980323 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
_em_software.reference_DOI 
'PARTICLE SELECTION'            ? 1  1 ? ? Topaz     0.24 ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 Latitude  3.5  ? 
MASKING                         ? 3  ? ? ? ?         ?    ? 
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC 4.0  ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ?    ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ?    ? 
'MODEL FITTING'                 ? 7  ? 1 ? Coot      0.96 ? 
OTHER                           ? 8  ? ? ? ?         ?    ? 
'INITIAL EULER ASSIGNMENT'      ? 9  1 ? ? cryoSPARC 4.0  ? 
'FINAL EULER ASSIGNMENT'        ? 10 1 ? ? cryoSPARC 4.0  ? 
CLASSIFICATION                  ? 11 1 ? ? ?         ?    ? 
RECONSTRUCTION                  ? 12 1 ? ? cryoSPARC 4.0  ? 
'MODEL REFINEMENT'              ? 13 ? 1 ? PHENIX    1.21 ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?         ?    ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ?    ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ?    ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ?    ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ?    ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ?    ? 
# 
_em_specimen.concentration           10 
_em_specimen.details                 'Monodisperse sample' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Cancer Institute (NIH/NCI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8ET6 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9DK9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N    . ALA A 1 2   ? 79.851  116.027 118.378 1.00 74.35  ? 2   ALA A N    1 
ATOM 2    C CA   . ALA A 1 2   ? 78.431  115.880 118.670 1.00 82.37  ? 2   ALA A CA   1 
ATOM 3    C C    . ALA A 1 2   ? 77.596  116.533 117.574 1.00 89.99  ? 2   ALA A C    1 
ATOM 4    O O    . ALA A 1 2   ? 78.119  116.903 116.523 1.00 91.16  ? 2   ALA A O    1 
ATOM 5    C CB   . ALA A 1 2   ? 78.103  116.487 120.023 1.00 84.24  ? 2   ALA A CB   1 
ATOM 6    H HA   . ALA A 1 2   ? 78.206  114.937 118.700 1.00 82.23  ? 2   ALA A HA   1 
ATOM 7    H HB1  . ALA A 1 2   ? 78.666  116.076 120.698 1.00 85.35  ? 2   ALA A HB1  1 
ATOM 8    H HB2  . ALA A 1 2   ? 78.272  117.442 119.988 1.00 86.48  ? 2   ALA A HB2  1 
ATOM 9    H HB3  . ALA A 1 2   ? 77.169  116.325 120.227 1.00 82.62  ? 2   ALA A HB3  1 
ATOM 10   N N    . PHE A 1 3   ? 76.298  116.676 117.823 1.00 91.95  ? 3   PHE A N    1 
ATOM 11   C CA   . PHE A 1 3   ? 75.428  117.335 116.864 1.00 93.99  ? 3   PHE A CA   1 
ATOM 12   C C    . PHE A 1 3   ? 75.792  118.814 116.760 1.00 89.51  ? 3   PHE A C    1 
ATOM 13   O O    . PHE A 1 3   ? 76.395  119.401 117.664 1.00 87.27  ? 3   PHE A O    1 
ATOM 14   C CB   . PHE A 1 3   ? 73.962  117.174 117.269 1.00 99.64  ? 3   PHE A CB   1 
ATOM 15   C CG   . PHE A 1 3   ? 72.987  117.647 116.226 1.00 98.78  ? 3   PHE A CG   1 
ATOM 16   C CD1  . PHE A 1 3   ? 72.965  117.071 114.966 1.00 95.91  ? 3   PHE A CD1  1 
ATOM 17   C CD2  . PHE A 1 3   ? 72.091  118.665 116.507 1.00 96.65  ? 3   PHE A CD2  1 
ATOM 18   C CE1  . PHE A 1 3   ? 72.070  117.503 114.005 1.00 98.97  ? 3   PHE A CE1  1 
ATOM 19   C CE2  . PHE A 1 3   ? 71.193  119.102 115.550 1.00 99.14  ? 3   PHE A CE2  1 
ATOM 20   C CZ   . PHE A 1 3   ? 71.183  118.520 114.298 1.00 103.31 ? 3   PHE A CZ   1 
ATOM 21   H H    . PHE A 1 3   ? 75.900  116.399 118.534 1.00 89.54  ? 3   PHE A H    1 
ATOM 22   H HA   . PHE A 1 3   ? 75.551  116.930 115.992 1.00 92.44  ? 3   PHE A HA   1 
ATOM 23   H HB2  . PHE A 1 3   ? 73.785  116.235 117.436 1.00 97.89  ? 3   PHE A HB2  1 
ATOM 24   H HB3  . PHE A 1 3   ? 73.803  117.687 118.077 1.00 96.94  ? 3   PHE A HB3  1 
ATOM 25   H HD1  . PHE A 1 3   ? 73.561  116.386 114.763 1.00 95.18  ? 3   PHE A HD1  1 
ATOM 26   H HD2  . PHE A 1 3   ? 72.094  119.061 117.349 1.00 95.92  ? 3   PHE A HD2  1 
ATOM 27   H HE1  . PHE A 1 3   ? 72.065  117.110 113.163 1.00 98.48  ? 3   PHE A HE1  1 
ATOM 28   H HE2  . PHE A 1 3   ? 70.596  119.786 115.750 1.00 99.60  ? 3   PHE A HE2  1 
ATOM 29   H HZ   . PHE A 1 3   ? 70.579  118.812 113.653 1.00 102.68 ? 3   PHE A HZ   1 
ATOM 30   N N    . SER A 1 4   ? 75.418  119.418 115.631 1.00 92.46  ? 4   SER A N    1 
ATOM 31   C CA   . SER A 1 4   ? 75.818  120.796 115.367 1.00 92.50  ? 4   SER A CA   1 
ATOM 32   C C    . SER A 1 4   ? 75.297  121.742 116.443 1.00 89.09  ? 4   SER A C    1 
ATOM 33   O O    . SER A 1 4   ? 76.025  122.627 116.906 1.00 93.14  ? 4   SER A O    1 
ATOM 34   C CB   . SER A 1 4   ? 75.320  121.229 113.989 1.00 96.07  ? 4   SER A CB   1 
ATOM 35   O OG   . SER A 1 4   ? 75.873  120.414 112.969 1.00 93.47  ? 4   SER A OG   1 
ATOM 36   H H    . SER A 1 4   ? 74.941  119.058 115.013 1.00 94.09  ? 4   SER A H    1 
ATOM 37   H HA   . SER A 1 4   ? 76.786  120.849 115.367 1.00 91.89  ? 4   SER A HA   1 
ATOM 38   H HB2  . SER A 1 4   ? 74.353  121.152 113.964 1.00 94.57  ? 4   SER A HB2  1 
ATOM 39   H HB3  . SER A 1 4   ? 75.583  122.149 113.833 1.00 95.08  ? 4   SER A HB3  1 
ATOM 40   H HG   . SER A 1 4   ? 76.711  120.473 112.977 1.00 93.21  ? 4   SER A HG   1 
ATOM 41   N N    . GLU A 1 5   ? 74.039  121.571 116.856 1.00 89.54  ? 5   GLU A N    1 
ATOM 42   C CA   . GLU A 1 5   ? 73.463  122.465 117.856 1.00 95.69  ? 5   GLU A CA   1 
ATOM 43   C C    . GLU A 1 5   ? 74.217  122.368 119.178 1.00 93.78  ? 5   GLU A C    1 
ATOM 44   O O    . GLU A 1 5   ? 74.577  123.387 119.780 1.00 92.95  ? 5   GLU A O    1 
ATOM 45   C CB   . GLU A 1 5   ? 71.984  122.136 118.058 1.00 99.71  ? 5   GLU A CB   1 
ATOM 46   C CG   . GLU A 1 5   ? 71.112  122.406 116.841 1.00 98.88  ? 5   GLU A CG   1 
ATOM 47   C CD   . GLU A 1 5   ? 71.068  123.874 116.466 1.00 101.74 ? 5   GLU A CD   1 
ATOM 48   O OE1  . GLU A 1 5   ? 70.468  124.665 117.224 1.00 102.94 ? 5   GLU A OE1  1 
ATOM 49   O OE2  . GLU A 1 5   ? 71.633  124.237 115.413 1.00 103.84 ? 5   GLU A OE2  1 
ATOM 50   H H    . GLU A 1 5   ? 73.507  120.956 116.576 1.00 93.18  ? 5   GLU A H    1 
ATOM 51   H HA   . GLU A 1 5   ? 73.531  123.380 117.541 1.00 95.45  ? 5   GLU A HA   1 
ATOM 52   H HB2  . GLU A 1 5   ? 71.902  121.195 118.277 1.00 97.45  ? 5   GLU A HB2  1 
ATOM 53   H HB3  . GLU A 1 5   ? 71.643  122.673 118.790 1.00 98.75  ? 5   GLU A HB3  1 
ATOM 54   H HG2  . GLU A 1 5   ? 71.465  121.913 116.084 1.00 97.70  ? 5   GLU A HG2  1 
ATOM 55   H HG3  . GLU A 1 5   ? 70.205  122.117 117.032 1.00 99.16  ? 5   GLU A HG3  1 
ATOM 56   N N    . LEU A 1 6   ? 74.463  121.143 119.647 1.00 88.75  ? 6   LEU A N    1 
ATOM 57   C CA   . LEU A 1 6   ? 75.146  120.962 120.924 1.00 84.68  ? 6   LEU A CA   1 
ATOM 58   C C    . LEU A 1 6   ? 76.576  121.485 120.866 1.00 79.49  ? 6   LEU A C    1 
ATOM 59   O O    . LEU A 1 6   ? 77.041  122.146 121.803 1.00 84.40  ? 6   LEU A O    1 
ATOM 60   C CB   . LEU A 1 6   ? 75.130  119.485 121.315 1.00 89.41  ? 6   LEU A CB   1 
ATOM 61   C CG   . LEU A 1 6   ? 73.744  118.838 121.368 1.00 96.40  ? 6   LEU A CG   1 
ATOM 62   C CD1  . LEU A 1 6   ? 73.864  117.326 121.364 1.00 94.78  ? 6   LEU A CD1  1 
ATOM 63   C CD2  . LEU A 1 6   ? 72.977  119.314 122.593 1.00 94.34  ? 6   LEU A CD2  1 
ATOM 64   H H    . LEU A 1 6   ? 74.249  120.411 119.248 1.00 90.65  ? 6   LEU A H    1 
ATOM 65   H HA   . LEU A 1 6   ? 74.672  121.459 121.609 1.00 86.64  ? 6   LEU A HA   1 
ATOM 66   H HB2  . LEU A 1 6   ? 75.658  118.990 120.669 1.00 90.14  ? 6   LEU A HB2  1 
ATOM 67   H HB3  . LEU A 1 6   ? 75.527  119.396 122.195 1.00 88.78  ? 6   LEU A HB3  1 
ATOM 68   H HG   . LEU A 1 6   ? 73.240  119.098 120.582 1.00 94.01  ? 6   LEU A HG   1 
ATOM 69   H HD11 . LEU A 1 6   ? 74.442  117.053 122.093 1.00 93.45  ? 6   LEU A HD11 1 
ATOM 70   H HD12 . LEU A 1 6   ? 72.981  116.940 121.476 1.00 95.11  ? 6   LEU A HD12 1 
ATOM 71   H HD13 . LEU A 1 6   ? 74.244  117.042 120.518 1.00 92.02  ? 6   LEU A HD13 1 
ATOM 72   H HD21 . LEU A 1 6   ? 72.851  120.274 122.533 1.00 91.64  ? 6   LEU A HD21 1 
ATOM 73   H HD22 . LEU A 1 6   ? 72.116  118.868 122.618 1.00 93.75  ? 6   LEU A HD22 1 
ATOM 74   H HD23 . LEU A 1 6   ? 73.486  119.095 123.389 1.00 93.28  ? 6   LEU A HD23 1 
ATOM 75   N N    . LEU A 1 7   ? 77.289  121.197 119.776 1.00 76.36  ? 7   LEU A N    1 
ATOM 76   C CA   . LEU A 1 7   ? 78.660  121.676 119.646 1.00 71.77  ? 7   LEU A CA   1 
ATOM 77   C C    . LEU A 1 7   ? 78.704  123.199 119.604 1.00 79.06  ? 7   LEU A C    1 
ATOM 78   O O    . LEU A 1 7   ? 79.578  123.820 120.220 1.00 78.68  ? 7   LEU A O    1 
ATOM 79   C CB   . LEU A 1 7   ? 79.301  121.084 118.391 1.00 68.32  ? 7   LEU A CB   1 
ATOM 80   C CG   . LEU A 1 7   ? 80.811  120.848 118.456 1.00 63.41  ? 7   LEU A CG   1 
ATOM 81   C CD1  . LEU A 1 7   ? 81.227  119.829 117.407 1.00 67.56  ? 7   LEU A CD1  1 
ATOM 82   C CD2  . LEU A 1 7   ? 81.578  122.148 118.282 1.00 74.70  ? 7   LEU A CD2  1 
ATOM 83   H H    . LEU A 1 7   ? 77.005  120.733 119.109 1.00 81.82  ? 7   LEU A H    1 
ATOM 84   H HA   . LEU A 1 7   ? 79.173  121.381 120.414 1.00 75.31  ? 7   LEU A HA   1 
ATOM 85   H HB2  . LEU A 1 7   ? 78.883  120.227 118.211 1.00 75.89  ? 7   LEU A HB2  1 
ATOM 86   H HB3  . LEU A 1 7   ? 79.134  121.686 117.650 1.00 74.31  ? 7   LEU A HB3  1 
ATOM 87   H HG   . LEU A 1 7   ? 81.035  120.485 119.328 1.00 66.99  ? 7   LEU A HG   1 
ATOM 88   H HD11 . LEU A 1 7   ? 80.963  120.153 116.532 1.00 70.58  ? 7   LEU A HD11 1 
ATOM 89   H HD12 . LEU A 1 7   ? 82.189  119.713 117.441 1.00 65.79  ? 7   LEU A HD12 1 
ATOM 90   H HD13 . LEU A 1 7   ? 80.784  118.986 117.594 1.00 71.13  ? 7   LEU A HD13 1 
ATOM 91   H HD21 . LEU A 1 7   ? 81.428  122.710 119.057 1.00 74.14  ? 7   LEU A HD21 1 
ATOM 92   H HD22 . LEU A 1 7   ? 82.523  121.946 118.197 1.00 73.51  ? 7   LEU A HD22 1 
ATOM 93   H HD23 . LEU A 1 7   ? 81.263  122.595 117.481 1.00 73.36  ? 7   LEU A HD23 1 
ATOM 94   N N    . ASP A 1 8   ? 77.767  123.817 118.882 1.00 87.53  ? 8   ASP A N    1 
ATOM 95   C CA   . ASP A 1 8   ? 77.704  125.274 118.843 1.00 85.90  ? 8   ASP A CA   1 
ATOM 96   C C    . ASP A 1 8   ? 77.413  125.846 120.224 1.00 83.64  ? 8   ASP A C    1 
ATOM 97   O O    . ASP A 1 8   ? 78.009  126.853 120.626 1.00 85.60  ? 8   ASP A O    1 
ATOM 98   C CB   . ASP A 1 8   ? 76.640  125.724 117.841 1.00 91.42  ? 8   ASP A CB   1 
ATOM 99   C CG   . ASP A 1 8   ? 76.522  127.233 117.751 1.00 100.46 ? 8   ASP A CG   1 
ATOM 100  O OD1  . ASP A 1 8   ? 77.451  127.934 118.205 1.00 111.63 ? 8   ASP A OD1  1 
ATOM 101  O OD2  . ASP A 1 8   ? 75.499  127.720 117.224 1.00 97.76  ? 8   ASP A OD2  1 
ATOM 102  H H    . ASP A 1 8   ? 77.165  123.420 118.412 1.00 87.25  ? 8   ASP A H    1 
ATOM 103  H HA   . ASP A 1 8   ? 78.560  125.621 118.548 1.00 86.44  ? 8   ASP A HA   1 
ATOM 104  H HB2  . ASP A 1 8   ? 76.872  125.388 116.961 1.00 91.22  ? 8   ASP A HB2  1 
ATOM 105  H HB3  . ASP A 1 8   ? 75.779  125.371 118.115 1.00 90.84  ? 8   ASP A HB3  1 
ATOM 106  N N    . GLN A 1 9   ? 76.499  125.218 120.968 1.00 84.54  ? 9   GLN A N    1 
ATOM 107  C CA   . GLN A 1 9   ? 76.213  125.679 122.322 1.00 86.99  ? 9   GLN A CA   1 
ATOM 108  C C    . GLN A 1 9   ? 77.453  125.588 123.200 1.00 84.94  ? 9   GLN A C    1 
ATOM 109  O O    . GLN A 1 9   ? 77.743  126.504 123.979 1.00 85.79  ? 9   GLN A O    1 
ATOM 110  C CB   . GLN A 1 9   ? 75.069  124.863 122.925 1.00 89.53  ? 9   GLN A CB   1 
ATOM 111  C CG   . GLN A 1 9   ? 73.682  125.405 122.611 1.00 93.13  ? 9   GLN A CG   1 
ATOM 112  C CD   . GLN A 1 9   ? 72.702  125.206 123.753 1.00 99.46  ? 9   GLN A CD   1 
ATOM 113  O OE1  . GLN A 1 9   ? 72.956  124.435 124.678 1.00 101.86 ? 9   GLN A OE1  1 
ATOM 114  N NE2  . GLN A 1 9   ? 71.574  125.902 123.691 1.00 96.39  ? 9   GLN A NE2  1 
ATOM 115  H H    . GLN A 1 9   ? 76.040  124.536 120.715 1.00 86.69  ? 9   GLN A H    1 
ATOM 116  H HA   . GLN A 1 9   ? 75.939  126.609 122.288 1.00 88.21  ? 9   GLN A HA   1 
ATOM 117  H HB2  . GLN A 1 9   ? 75.117  123.957 122.581 1.00 88.46  ? 9   GLN A HB2  1 
ATOM 118  H HB3  . GLN A 1 9   ? 75.174  124.852 123.889 1.00 89.82  ? 9   GLN A HB3  1 
ATOM 119  H HG2  . GLN A 1 9   ? 73.743  126.356 122.434 1.00 92.65  ? 9   GLN A HG2  1 
ATOM 120  H HG3  . GLN A 1 9   ? 73.332  124.944 121.833 1.00 91.80  ? 9   GLN A HG3  1 
ATOM 121  H HE21 . GLN A 1 9   ? 71.431  126.431 123.028 1.00 95.15  ? 9   GLN A HE21 1 
ATOM 122  H HE22 . GLN A 1 9   ? 70.985  125.825 124.313 1.00 97.03  ? 9   GLN A HE22 1 
ATOM 123  N N    . VAL A 1 10  ? 78.198  124.487 123.089 1.00 80.65  ? 10  VAL A N    1 
ATOM 124  C CA   . VAL A 1 10  ? 79.442  124.354 123.838 1.00 74.32  ? 10  VAL A CA   1 
ATOM 125  C C    . VAL A 1 10  ? 80.476  125.352 123.333 1.00 78.74  ? 10  VAL A C    1 
ATOM 126  O O    . VAL A 1 10  ? 81.254  125.912 124.114 1.00 77.23  ? 10  VAL A O    1 
ATOM 127  C CB   . VAL A 1 10  ? 79.962  122.908 123.748 1.00 69.88  ? 10  VAL A CB   1 
ATOM 128  C CG1  . VAL A 1 10  ? 81.440  122.846 124.092 1.00 73.25  ? 10  VAL A CG1  1 
ATOM 129  C CG2  . VAL A 1 10  ? 79.163  122.002 124.662 1.00 68.36  ? 10  VAL A CG2  1 
ATOM 130  H H    . VAL A 1 10  ? 78.006  123.812 122.592 1.00 81.76  ? 10  VAL A H    1 
ATOM 131  H HA   . VAL A 1 10  ? 79.269  124.551 124.772 1.00 76.66  ? 10  VAL A HA   1 
ATOM 132  H HB   . VAL A 1 10  ? 79.852  122.589 122.838 1.00 74.80  ? 10  VAL A HB   1 
ATOM 133  H HG11 . VAL A 1 10  ? 81.669  121.925 124.292 1.00 74.31  ? 10  VAL A HG11 1 
ATOM 134  H HG12 . VAL A 1 10  ? 81.961  123.156 123.335 1.00 74.43  ? 10  VAL A HG12 1 
ATOM 135  H HG13 . VAL A 1 10  ? 81.609  123.403 124.868 1.00 75.45  ? 10  VAL A HG13 1 
ATOM 136  H HG21 . VAL A 1 10  ? 79.490  121.096 124.555 1.00 70.92  ? 10  VAL A HG21 1 
ATOM 137  H HG22 . VAL A 1 10  ? 79.281  122.293 125.580 1.00 70.77  ? 10  VAL A HG22 1 
ATOM 138  H HG23 . VAL A 1 10  ? 78.226  122.049 124.416 1.00 74.24  ? 10  VAL A HG23 1 
ATOM 139  N N    . GLY A 1 11  ? 80.501  125.588 122.024 1.00 82.15  ? 11  GLY A N    1 
ATOM 140  C CA   . GLY A 1 11  ? 81.472  126.477 121.417 1.00 84.26  ? 11  GLY A CA   1 
ATOM 141  C C    . GLY A 1 11  ? 82.296  125.778 120.358 1.00 85.38  ? 11  GLY A C    1 
ATOM 142  O O    . GLY A 1 11  ? 83.011  124.816 120.652 1.00 75.93  ? 11  GLY A O    1 
ATOM 143  H H    . GLY A 1 11  ? 79.955  125.236 121.460 1.00 81.49  ? 11  GLY A H    1 
ATOM 144  H HA2  . GLY A 1 11  ? 81.013  127.226 121.006 1.00 83.28  ? 11  GLY A HA2  1 
ATOM 145  H HA3  . GLY A 1 11  ? 82.075  126.820 122.095 1.00 82.10  ? 11  GLY A HA3  1 
ATOM 146  N N    . GLY A 1 12  ? 82.205  126.256 119.116 1.00 89.30  ? 12  GLY A N    1 
ATOM 147  C CA   . GLY A 1 12  ? 82.913  125.597 118.030 1.00 86.02  ? 12  GLY A CA   1 
ATOM 148  C C    . GLY A 1 12  ? 84.419  125.657 118.196 1.00 83.01  ? 12  GLY A C    1 
ATOM 149  O O    . GLY A 1 12  ? 85.116  124.652 118.031 1.00 74.24  ? 12  GLY A O    1 
ATOM 150  H H    . GLY A 1 12  ? 81.749  126.946 118.883 1.00 85.85  ? 12  GLY A H    1 
ATOM 151  H HA2  . GLY A 1 12  ? 82.647  124.666 117.989 1.00 82.78  ? 12  GLY A HA2  1 
ATOM 152  H HA3  . GLY A 1 12  ? 82.680  126.020 117.189 1.00 84.91  ? 12  GLY A HA3  1 
ATOM 153  N N    . LEU A 1 13  ? 84.941  126.836 118.526 1.00 86.29  ? 13  LEU A N    1 
ATOM 154  C CA   . LEU A 1 13  ? 86.375  127.051 118.672 1.00 76.76  ? 13  LEU A CA   1 
ATOM 155  C C    . LEU A 1 13  ? 86.648  127.713 120.013 1.00 69.84  ? 13  LEU A C    1 
ATOM 156  O O    . LEU A 1 13  ? 85.987  128.693 120.371 1.00 65.96  ? 13  LEU A O    1 
ATOM 157  C CB   . LEU A 1 13  ? 86.921  127.916 117.532 1.00 74.98  ? 13  LEU A CB   1 
ATOM 158  C CG   . LEU A 1 13  ? 87.747  127.186 116.470 1.00 72.84  ? 13  LEU A CG   1 
ATOM 159  C CD1  . LEU A 1 13  ? 89.086  126.751 117.042 1.00 68.70  ? 13  LEU A CD1  1 
ATOM 160  C CD2  . LEU A 1 13  ? 86.987  125.993 115.910 1.00 73.97  ? 13  LEU A CD2  1 
ATOM 161  H H    . LEU A 1 13  ? 84.473  127.541 118.674 1.00 82.35  ? 13  LEU A H    1 
ATOM 162  H HA   . LEU A 1 13  ? 86.834  126.197 118.659 1.00 76.98  ? 13  LEU A HA   1 
ATOM 163  H HB2  . LEU A 1 13  ? 86.171  128.330 117.078 1.00 76.08  ? 13  LEU A HB2  1 
ATOM 164  H HB3  . LEU A 1 13  ? 87.486  128.605 117.915 1.00 74.37  ? 13  LEU A HB3  1 
ATOM 165  H HG   . LEU A 1 13  ? 87.922  127.796 115.737 1.00 74.61  ? 13  LEU A HG   1 
ATOM 166  H HD11 . LEU A 1 13  ? 89.590  126.293 116.351 1.00 69.33  ? 13  LEU A HD11 1 
ATOM 167  H HD12 . LEU A 1 13  ? 89.571  127.536 117.340 1.00 68.73  ? 13  LEU A HD12 1 
ATOM 168  H HD13 . LEU A 1 13  ? 88.932  126.153 117.790 1.00 71.48  ? 13  LEU A HD13 1 
ATOM 169  H HD21 . LEU A 1 13  ? 87.435  125.684 115.108 1.00 74.47  ? 13  LEU A HD21 1 
ATOM 170  H HD22 . LEU A 1 13  ? 86.974  125.285 116.573 1.00 73.78  ? 13  LEU A HD22 1 
ATOM 171  H HD23 . LEU A 1 13  ? 86.081  126.267 115.698 1.00 75.21  ? 13  LEU A HD23 1 
ATOM 172  N N    . GLY A 1 14  ? 87.617  127.182 120.743 1.00 66.71  ? 14  GLY A N    1 
ATOM 173  C CA   . GLY A 1 14  ? 87.956  127.739 122.032 1.00 69.86  ? 14  GLY A CA   1 
ATOM 174  C C    . GLY A 1 14  ? 89.234  127.140 122.573 1.00 65.15  ? 14  GLY A C    1 
ATOM 175  O O    . GLY A 1 14  ? 90.009  126.528 121.838 1.00 58.57  ? 14  GLY A O    1 
ATOM 176  H H    . GLY A 1 14  ? 88.089  126.502 120.511 1.00 68.93  ? 14  GLY A H    1 
ATOM 177  H HA2  . GLY A 1 14  ? 88.075  128.698 121.951 1.00 68.55  ? 14  GLY A HA2  1 
ATOM 178  H HA3  . GLY A 1 14  ? 87.237  127.569 122.658 1.00 70.28  ? 14  GLY A HA3  1 
ATOM 179  N N    . ARG A 1 15  ? 89.437  127.318 123.880 1.00 65.56  ? 15  ARG A N    1 
ATOM 180  C CA   . ARG A 1 15  ? 90.671  126.860 124.514 1.00 64.76  ? 15  ARG A CA   1 
ATOM 181  C C    . ARG A 1 15  ? 90.905  125.376 124.260 1.00 59.83  ? 15  ARG A C    1 
ATOM 182  O O    . ARG A 1 15  ? 92.014  124.958 123.903 1.00 58.85  ? 15  ARG A O    1 
ATOM 183  C CB   . ARG A 1 15  ? 90.620  127.125 126.020 1.00 61.58  ? 15  ARG A CB   1 
ATOM 184  C CG   . ARG A 1 15  ? 90.523  128.586 126.422 1.00 61.74  ? 15  ARG A CG   1 
ATOM 185  C CD   . ARG A 1 15  ? 90.466  128.716 127.939 1.00 60.87  ? 15  ARG A CD   1 
ATOM 186  N NE   . ARG A 1 15  ? 89.565  129.771 128.389 1.00 65.70  ? 15  ARG A NE   1 
ATOM 187  C CZ   . ARG A 1 15  ? 89.105  129.881 129.629 1.00 66.49  ? 15  ARG A CZ   1 
ATOM 188  N NH1  . ARG A 1 15  ? 89.438  129.013 130.571 1.00 65.71  ? 15  ARG A NH1  1 
ATOM 189  N NH2  . ARG A 1 15  ? 88.291  130.889 129.932 1.00 67.83  ? 15  ARG A NH2  1 
ATOM 190  H H    . ARG A 1 15  ? 88.879  127.696 124.416 1.00 65.02  ? 15  ARG A H    1 
ATOM 191  H HA   . ARG A 1 15  ? 91.420  127.354 124.144 1.00 65.45  ? 15  ARG A HA   1 
ATOM 192  H HB2  . ARG A 1 15  ? 89.843  126.671 126.383 1.00 62.79  ? 15  ARG A HB2  1 
ATOM 193  H HB3  . ARG A 1 15  ? 91.423  126.762 126.424 1.00 60.32  ? 15  ARG A HB3  1 
ATOM 194  H HG2  . ARG A 1 15  ? 91.306  129.061 126.102 1.00 61.02  ? 15  ARG A HG2  1 
ATOM 195  H HG3  . ARG A 1 15  ? 89.715  128.973 126.048 1.00 64.45  ? 15  ARG A HG3  1 
ATOM 196  H HD2  . ARG A 1 15  ? 90.156  127.877 128.315 1.00 62.26  ? 15  ARG A HD2  1 
ATOM 197  H HD3  . ARG A 1 15  ? 91.354  128.919 128.272 1.00 61.50  ? 15  ARG A HD3  1 
ATOM 198  H HE   . ARG A 1 15  ? 89.385  130.406 127.838 1.00 64.71  ? 15  ARG A HE   1 
ATOM 199  H HH11 . ARG A 1 15  ? 89.963  128.357 130.389 1.00 64.11  ? 15  ARG A HH11 1 
ATOM 200  H HH12 . ARG A 1 15  ? 89.127  129.105 131.368 1.00 66.18  ? 15  ARG A HH12 1 
ATOM 201  H HH21 . ARG A 1 15  ? 88.068  131.459 129.328 1.00 66.89  ? 15  ARG A HH21 1 
ATOM 202  H HH22 . ARG A 1 15  ? 87.988  130.969 130.733 1.00 66.68  ? 15  ARG A HH22 1 
ATOM 203  N N    . PHE A 1 16  ? 89.864  124.562 124.449 1.00 55.75  ? 16  PHE A N    1 
ATOM 204  C CA   . PHE A 1 16  ? 90.039  123.116 124.391 1.00 58.11  ? 16  PHE A CA   1 
ATOM 205  C C    . PHE A 1 16  ? 90.508  122.670 123.014 1.00 61.82  ? 16  PHE A C    1 
ATOM 206  O O    . PHE A 1 16  ? 91.327  121.754 122.902 1.00 63.44  ? 16  PHE A O    1 
ATOM 207  C CB   . PHE A 1 16  ? 88.738  122.407 124.758 1.00 52.34  ? 16  PHE A CB   1 
ATOM 208  C CG   . PHE A 1 16  ? 88.849  120.908 124.760 1.00 56.22  ? 16  PHE A CG   1 
ATOM 209  C CD1  . PHE A 1 16  ? 89.301  120.233 125.881 1.00 60.66  ? 16  PHE A CD1  1 
ATOM 210  C CD2  . PHE A 1 16  ? 88.515  120.176 123.632 1.00 55.22  ? 16  PHE A CD2  1 
ATOM 211  C CE1  . PHE A 1 16  ? 89.405  118.854 125.880 1.00 60.42  ? 16  PHE A CE1  1 
ATOM 212  C CE2  . PHE A 1 16  ? 88.619  118.799 123.626 1.00 58.46  ? 16  PHE A CE2  1 
ATOM 213  C CZ   . PHE A 1 16  ? 89.064  118.137 124.751 1.00 60.43  ? 16  PHE A CZ   1 
ATOM 214  H H    . PHE A 1 16  ? 89.058  124.821 124.605 1.00 57.42  ? 16  PHE A H    1 
ATOM 215  H HA   . PHE A 1 16  ? 90.717  122.851 125.033 1.00 60.87  ? 16  PHE A HA   1 
ATOM 216  H HB2  . PHE A 1 16  ? 88.471  122.688 125.647 1.00 54.56  ? 16  PHE A HB2  1 
ATOM 217  H HB3  . PHE A 1 16  ? 88.055  122.653 124.115 1.00 54.75  ? 16  PHE A HB3  1 
ATOM 218  H HD1  . PHE A 1 16  ? 89.529  120.711 126.646 1.00 59.37  ? 16  PHE A HD1  1 
ATOM 219  H HD2  . PHE A 1 16  ? 88.214  120.618 122.871 1.00 55.71  ? 16  PHE A HD2  1 
ATOM 220  H HE1  . PHE A 1 16  ? 89.706  118.409 126.639 1.00 59.36  ? 16  PHE A HE1  1 
ATOM 221  H HE2  . PHE A 1 16  ? 88.390  118.319 122.863 1.00 58.68  ? 16  PHE A HE2  1 
ATOM 222  H HZ   . PHE A 1 16  ? 89.136  117.210 124.748 1.00 60.38  ? 16  PHE A HZ   1 
ATOM 223  N N    . GLN A 1 17  ? 89.981  123.284 121.954 1.00 64.82  ? 17  GLN A N    1 
ATOM 224  C CA   . GLN A 1 17  ? 90.403  122.909 120.609 1.00 64.27  ? 17  GLN A CA   1 
ATOM 225  C C    . GLN A 1 17  ? 91.894  123.161 120.416 1.00 62.08  ? 17  GLN A C    1 
ATOM 226  O O    . GLN A 1 17  ? 92.618  122.301 119.900 1.00 59.22  ? 17  GLN A O    1 
ATOM 227  C CB   . GLN A 1 17  ? 89.579  123.684 119.571 1.00 68.42  ? 17  GLN A CB   1 
ATOM 228  C CG   . GLN A 1 17  ? 88.112  123.235 119.361 1.00 68.70  ? 17  GLN A CG   1 
ATOM 229  C CD   . GLN A 1 17  ? 87.881  121.721 119.220 1.00 68.67  ? 17  GLN A CD   1 
ATOM 230  O OE1  . GLN A 1 17  ? 86.736  121.273 119.239 1.00 69.24  ? 17  GLN A OE1  1 
ATOM 231  N NE2  . GLN A 1 17  ? 88.935  120.962 118.934 1.00 66.29  ? 17  GLN A NE2  1 
ATOM 232  H H    . GLN A 1 17  ? 89.384  123.902 121.983 1.00 63.44  ? 17  GLN A H    1 
ATOM 233  H HA   . GLN A 1 17  ? 90.265  121.958 120.535 1.00 62.49  ? 17  GLN A HA   1 
ATOM 234  H HB2  . GLN A 1 17  ? 89.553  124.615 119.846 1.00 67.85  ? 17  GLN A HB2  1 
ATOM 235  H HB3  . GLN A 1 17  ? 90.023  123.617 118.711 1.00 67.15  ? 17  GLN A HB3  1 
ATOM 236  H HG2  . GLN A 1 17  ? 87.595  123.535 120.124 1.00 67.29  ? 17  GLN A HG2  1 
ATOM 237  H HG3  . GLN A 1 17  ? 87.771  123.662 118.558 1.00 70.14  ? 17  GLN A HG3  1 
ATOM 238  H HE21 . GLN A 1 17  ? 89.723  121.291 118.884 1.00 67.47  ? 17  GLN A HE21 1 
ATOM 239  H HE22 . GLN A 1 17  ? 88.827  120.116 118.833 1.00 69.06  ? 17  GLN A HE22 1 
ATOM 240  N N    . VAL A 1 18  ? 92.377  124.329 120.845 1.00 55.60  ? 18  VAL A N    1 
ATOM 241  C CA   . VAL A 1 18  ? 93.800  124.636 120.704 1.00 56.38  ? 18  VAL A CA   1 
ATOM 242  C C    . VAL A 1 18  ? 94.635  123.659 121.519 1.00 57.58  ? 18  VAL A C    1 
ATOM 243  O O    . VAL A 1 18  ? 95.651  123.135 121.045 1.00 56.55  ? 18  VAL A O    1 
ATOM 244  C CB   . VAL A 1 18  ? 94.091  126.093 121.113 1.00 60.05  ? 18  VAL A CB   1 
ATOM 245  C CG1  . VAL A 1 18  ? 95.398  126.569 120.492 1.00 63.29  ? 18  VAL A CG1  1 
ATOM 246  C CG2  . VAL A 1 18  ? 92.958  127.018 120.699 1.00 59.69  ? 18  VAL A CG2  1 
ATOM 247  H H    . VAL A 1 18  ? 91.908  124.944 121.221 1.00 58.72  ? 18  VAL A H    1 
ATOM 248  H HA   . VAL A 1 18  ? 94.049  124.533 119.772 1.00 57.14  ? 18  VAL A HA   1 
ATOM 249  H HB   . VAL A 1 18  ? 94.178  126.137 122.079 1.00 59.97  ? 18  VAL A HB   1 
ATOM 250  H HG11 . VAL A 1 18  ? 95.563  127.484 120.770 1.00 60.81  ? 18  VAL A HG11 1 
ATOM 251  H HG12 . VAL A 1 18  ? 96.119  125.997 120.798 1.00 62.61  ? 18  VAL A HG12 1 
ATOM 252  H HG13 . VAL A 1 18  ? 95.329  126.526 119.525 1.00 62.84  ? 18  VAL A HG13 1 
ATOM 253  H HG21 . VAL A 1 18  ? 93.297  127.926 120.664 1.00 60.42  ? 18  VAL A HG21 1 
ATOM 254  H HG22 . VAL A 1 18  ? 92.631  126.752 119.825 1.00 61.17  ? 18  VAL A HG22 1 
ATOM 255  H HG23 . VAL A 1 18  ? 92.246  126.958 121.353 1.00 59.01  ? 18  VAL A HG23 1 
ATOM 256  N N    . LEU A 1 19  ? 94.225  123.405 122.764 1.00 50.82  ? 19  LEU A N    1 
ATOM 257  C CA   . LEU A 1 19  ? 94.993  122.508 123.622 1.00 45.03  ? 19  LEU A CA   1 
ATOM 258  C C    . LEU A 1 19  ? 95.061  121.106 123.026 1.00 49.43  ? 19  LEU A C    1 
ATOM 259  O O    . LEU A 1 19  ? 96.132  120.488 122.979 1.00 54.66  ? 19  LEU A O    1 
ATOM 260  C CB   . LEU A 1 19  ? 94.376  122.471 125.023 1.00 45.21  ? 19  LEU A CB   1 
ATOM 261  C CG   . LEU A 1 19  ? 94.592  123.659 125.973 1.00 44.56  ? 19  LEU A CG   1 
ATOM 262  C CD1  . LEU A 1 19  ? 94.585  123.176 127.418 1.00 44.34  ? 19  LEU A CD1  1 
ATOM 263  C CD2  . LEU A 1 19  ? 95.878  124.425 125.683 1.00 49.78  ? 19  LEU A CD2  1 
ATOM 264  H H    . LEU A 1 19  ? 93.519  123.735 123.126 1.00 53.65  ? 19  LEU A H    1 
ATOM 265  H HA   . LEU A 1 19  ? 95.902  122.837 123.687 1.00 48.68  ? 19  LEU A HA   1 
ATOM 266  H HB2  . LEU A 1 19  ? 93.416  122.375 124.918 1.00 50.68  ? 19  LEU A HB2  1 
ATOM 267  H HB3  . LEU A 1 19  ? 94.719  121.685 125.476 1.00 47.22  ? 19  LEU A HB3  1 
ATOM 268  H HG   . LEU A 1 19  ? 93.853  124.279 125.868 1.00 49.56  ? 19  LEU A HG   1 
ATOM 269  H HD11 . LEU A 1 19  ? 94.716  123.937 128.006 1.00 44.82  ? 19  LEU A HD11 1 
ATOM 270  H HD12 . LEU A 1 19  ? 93.731  122.756 127.607 1.00 45.13  ? 19  LEU A HD12 1 
ATOM 271  H HD13 . LEU A 1 19  ? 95.303  122.536 127.541 1.00 46.60  ? 19  LEU A HD13 1 
ATOM 272  H HD21 . LEU A 1 19  ? 96.000  125.104 126.365 1.00 50.98  ? 19  LEU A HD21 1 
ATOM 273  H HD22 . LEU A 1 19  ? 96.624  123.805 125.698 1.00 51.33  ? 19  LEU A HD22 1 
ATOM 274  H HD23 . LEU A 1 19  ? 95.810  124.842 124.810 1.00 50.64  ? 19  LEU A HD23 1 
ATOM 275  N N    . GLN A 1 20  ? 93.923  120.589 122.557 1.00 51.58  ? 20  GLN A N    1 
ATOM 276  C CA   . GLN A 1 20  ? 93.891  119.245 121.992 1.00 53.57  ? 20  GLN A CA   1 
ATOM 277  C C    . GLN A 1 20  ? 94.711  119.164 120.711 1.00 53.86  ? 20  GLN A C    1 
ATOM 278  O O    . GLN A 1 20  ? 95.422  118.177 120.488 1.00 53.23  ? 20  GLN A O    1 
ATOM 279  C CB   . GLN A 1 20  ? 92.441  118.817 121.745 1.00 52.08  ? 20  GLN A CB   1 
ATOM 280  C CG   . GLN A 1 20  ? 92.212  117.984 120.487 1.00 61.82  ? 20  GLN A CG   1 
ATOM 281  C CD   . GLN A 1 20  ? 90.759  117.579 120.316 1.00 71.52  ? 20  GLN A CD   1 
ATOM 282  O OE1  . GLN A 1 20  ? 90.049  117.345 121.294 1.00 71.36  ? 20  GLN A OE1  1 
ATOM 283  N NE2  . GLN A 1 20  ? 90.310  117.493 119.068 1.00 69.53  ? 20  GLN A NE2  1 
ATOM 284  H H    . GLN A 1 20  ? 93.165  120.996 122.555 1.00 54.36  ? 20  GLN A H    1 
ATOM 285  H HA   . GLN A 1 20  ? 94.278  118.627 122.631 1.00 54.89  ? 20  GLN A HA   1 
ATOM 286  H HB2  . GLN A 1 20  ? 92.143  118.288 122.501 1.00 54.74  ? 20  GLN A HB2  1 
ATOM 287  H HB3  . GLN A 1 20  ? 91.892  119.614 121.670 1.00 57.10  ? 20  GLN A HB3  1 
ATOM 288  H HG2  . GLN A 1 20  ? 92.453  118.505 119.706 1.00 62.00  ? 20  GLN A HG2  1 
ATOM 289  H HG3  . GLN A 1 20  ? 92.748  117.177 120.534 1.00 60.87  ? 20  GLN A HG3  1 
ATOM 290  H HE21 . GLN A 1 20  ? 90.835  117.663 118.409 1.00 67.79  ? 20  GLN A HE21 1 
ATOM 291  H HE22 . GLN A 1 20  ? 89.494  117.266 118.920 1.00 67.64  ? 20  GLN A HE22 1 
ATOM 292  N N    . THR A 1 21  ? 94.625  120.183 119.852 1.00 55.31  ? 21  THR A N    1 
ATOM 293  C CA   . THR A 1 21  ? 95.427  120.177 118.633 1.00 60.09  ? 21  THR A CA   1 
ATOM 294  C C    . THR A 1 21  ? 96.915  120.200 118.957 1.00 59.98  ? 21  THR A C    1 
ATOM 295  O O    . THR A 1 21  ? 97.702  119.466 118.347 1.00 60.40  ? 21  THR A O    1 
ATOM 296  C CB   . THR A 1 21  ? 95.056  121.369 117.750 1.00 62.65  ? 21  THR A CB   1 
ATOM 297  O OG1  . THR A 1 21  ? 93.654  121.639 117.865 1.00 62.05  ? 21  THR A OG1  1 
ATOM 298  C CG2  . THR A 1 21  ? 95.402  121.085 116.295 1.00 61.44  ? 21  THR A CG2  1 
ATOM 299  H H    . THR A 1 21  ? 94.121  120.872 119.951 1.00 56.29  ? 21  THR A H    1 
ATOM 300  H HA   . THR A 1 21  ? 95.241  119.365 118.136 1.00 58.39  ? 21  THR A HA   1 
ATOM 301  H HB   . THR A 1 21  ? 95.557  122.149 118.035 1.00 61.32  ? 21  THR A HB   1 
ATOM 302  H HG1  . THR A 1 21  ? 93.501  122.068 118.569 1.00 58.82  ? 21  THR A HG1  1 
ATOM 303  H HG21 . THR A 1 21  ? 95.163  121.847 115.744 1.00 61.58  ? 21  THR A HG21 1 
ATOM 304  H HG22 . THR A 1 21  ? 96.353  120.919 116.208 1.00 60.04  ? 21  THR A HG22 1 
ATOM 305  H HG23 . THR A 1 21  ? 94.915  120.306 115.985 1.00 58.62  ? 21  THR A HG23 1 
ATOM 306  N N    . VAL A 1 22  ? 97.320  121.033 119.917 1.00 54.93  ? 22  VAL A N    1 
ATOM 307  C CA   . VAL A 1 22  ? 98.728  121.093 120.297 1.00 50.86  ? 22  VAL A CA   1 
ATOM 308  C C    . VAL A 1 22  ? 99.181  119.746 120.840 1.00 55.33  ? 22  VAL A C    1 
ATOM 309  O O    . VAL A 1 22  ? 100.273 119.263 120.517 1.00 57.72  ? 22  VAL A O    1 
ATOM 310  C CB   . VAL A 1 22  ? 98.956  122.222 121.320 1.00 47.94  ? 22  VAL A CB   1 
ATOM 311  C CG1  . VAL A 1 22  ? 100.327 122.091 121.970 1.00 53.66  ? 22  VAL A CG1  1 
ATOM 312  C CG2  . VAL A 1 22  ? 98.796  123.583 120.657 1.00 49.22  ? 22  VAL A CG2  1 
ATOM 313  H H    . VAL A 1 22  ? 96.806  121.565 120.357 1.00 55.02  ? 22  VAL A H    1 
ATOM 314  H HA   . VAL A 1 22  ? 99.258  121.292 119.510 1.00 52.03  ? 22  VAL A HA   1 
ATOM 315  H HB   . VAL A 1 22  ? 98.288  122.152 122.020 1.00 51.36  ? 22  VAL A HB   1 
ATOM 316  H HG11 . VAL A 1 22  ? 100.551 122.930 122.403 1.00 53.28  ? 22  VAL A HG11 1 
ATOM 317  H HG12 . VAL A 1 22  ? 100.302 121.380 122.629 1.00 54.27  ? 22  VAL A HG12 1 
ATOM 318  H HG13 . VAL A 1 22  ? 100.983 121.889 121.285 1.00 53.72  ? 22  VAL A HG13 1 
ATOM 319  H HG21 . VAL A 1 22  ? 98.475  123.457 119.750 1.00 52.46  ? 22  VAL A HG21 1 
ATOM 320  H HG22 . VAL A 1 22  ? 98.155  124.106 121.164 1.00 50.30  ? 22  VAL A HG22 1 
ATOM 321  H HG23 . VAL A 1 22  ? 99.654  124.034 120.646 1.00 52.52  ? 22  VAL A HG23 1 
ATOM 322  N N    . ALA A 1 23  ? 98.349  119.118 121.672 1.00 54.25  ? 23  ALA A N    1 
ATOM 323  C CA   . ALA A 1 23  ? 98.710  117.827 122.245 1.00 50.05  ? 23  ALA A CA   1 
ATOM 324  C C    . ALA A 1 23  ? 98.832  116.752 121.171 1.00 48.58  ? 23  ALA A C    1 
ATOM 325  O O    . ALA A 1 23  ? 99.742  115.917 121.221 1.00 46.63  ? 23  ALA A O    1 
ATOM 326  C CB   . ALA A 1 23  ? 97.678  117.420 123.295 1.00 50.22  ? 23  ALA A CB   1 
ATOM 327  H H    . ALA A 1 23  ? 97.580  119.415 121.917 1.00 53.47  ? 23  ALA A H    1 
ATOM 328  H HA   . ALA A 1 23  ? 99.570  117.907 122.687 1.00 50.75  ? 23  ALA A HA   1 
ATOM 329  H HB1  . ALA A 1 23  ? 97.878  116.523 123.601 1.00 49.03  ? 23  ALA A HB1  1 
ATOM 330  H HB2  . ALA A 1 23  ? 97.719  118.042 124.038 1.00 52.19  ? 23  ALA A HB2  1 
ATOM 331  H HB3  . ALA A 1 23  ? 96.795  117.439 122.893 1.00 51.36  ? 23  ALA A HB3  1 
ATOM 332  N N    . LEU A 1 24  ? 97.923  116.752 120.194 1.00 51.75  ? 24  LEU A N    1 
ATOM 333  C CA   . LEU A 1 24  ? 97.867  115.654 119.234 1.00 53.09  ? 24  LEU A CA   1 
ATOM 334  C C    . LEU A 1 24  ? 98.854  115.815 118.083 1.00 51.05  ? 24  LEU A C    1 
ATOM 335  O O    . LEU A 1 24  ? 99.295  114.810 117.515 1.00 54.47  ? 24  LEU A O    1 
ATOM 336  C CB   . LEU A 1 24  ? 96.449  115.516 118.676 1.00 54.38  ? 24  LEU A CB   1 
ATOM 337  C CG   . LEU A 1 24  ? 95.582  114.433 119.321 1.00 54.79  ? 24  LEU A CG   1 
ATOM 338  C CD1  . LEU A 1 24  ? 95.614  114.531 120.833 1.00 60.95  ? 24  LEU A CD1  1 
ATOM 339  C CD2  . LEU A 1 24  ? 94.155  114.518 118.813 1.00 53.17  ? 24  LEU A CD2  1 
ATOM 340  H H    . LEU A 1 24  ? 97.336  117.368 120.069 1.00 52.86  ? 24  LEU A H    1 
ATOM 341  H HA   . LEU A 1 24  ? 98.088  114.828 119.691 1.00 53.43  ? 24  LEU A HA   1 
ATOM 342  H HB2  . LEU A 1 24  ? 95.990  116.363 118.793 1.00 54.51  ? 24  LEU A HB2  1 
ATOM 343  H HB3  . LEU A 1 24  ? 96.512  115.312 117.730 1.00 54.40  ? 24  LEU A HB3  1 
ATOM 344  H HG   . LEU A 1 24  ? 95.933  113.563 119.073 1.00 54.33  ? 24  LEU A HG   1 
ATOM 345  H HD11 . LEU A 1 24  ? 94.978  113.894 121.194 1.00 59.67  ? 24  LEU A HD11 1 
ATOM 346  H HD12 . LEU A 1 24  ? 96.505  114.320 121.152 1.00 58.29  ? 24  LEU A HD12 1 
ATOM 347  H HD13 . LEU A 1 24  ? 95.368  115.431 121.098 1.00 56.87  ? 24  LEU A HD13 1 
ATOM 348  H HD21 . LEU A 1 24  ? 93.605  113.892 119.310 1.00 54.14  ? 24  LEU A HD21 1 
ATOM 349  H HD22 . LEU A 1 24  ? 93.827  115.422 118.942 1.00 54.12  ? 24  LEU A HD22 1 
ATOM 350  H HD23 . LEU A 1 24  ? 94.146  114.292 117.871 1.00 53.16  ? 24  LEU A HD23 1 
ATOM 351  N N    . VAL A 1 25  ? 99.206  117.047 117.710 1.00 51.29  ? 25  VAL A N    1 
ATOM 352  C CA   . VAL A 1 25  ? 100.108 117.234 116.577 1.00 56.64  ? 25  VAL A CA   1 
ATOM 353  C C    . VAL A 1 25  ? 101.516 116.761 116.920 1.00 60.18  ? 25  VAL A C    1 
ATOM 354  O O    . VAL A 1 25  ? 102.220 116.205 116.069 1.00 63.26  ? 25  VAL A O    1 
ATOM 355  C CB   . VAL A 1 25  ? 100.100 118.704 116.123 1.00 59.13  ? 25  VAL A CB   1 
ATOM 356  C CG1  . VAL A 1 25  ? 101.176 118.940 115.079 1.00 57.02  ? 25  VAL A CG1  1 
ATOM 357  C CG2  . VAL A 1 25  ? 98.736  119.075 115.560 1.00 58.69  ? 25  VAL A CG2  1 
ATOM 358  H H    . VAL A 1 25  ? 98.942  117.774 118.087 1.00 53.70  ? 25  VAL A H    1 
ATOM 359  H HA   . VAL A 1 25  ? 99.789  116.695 115.836 1.00 55.23  ? 25  VAL A HA   1 
ATOM 360  H HB   . VAL A 1 25  ? 100.282 119.277 116.885 1.00 58.17  ? 25  VAL A HB   1 
ATOM 361  H HG11 . VAL A 1 25  ? 100.983 119.767 114.611 1.00 57.23  ? 25  VAL A HG11 1 
ATOM 362  H HG12 . VAL A 1 25  ? 102.039 119.003 115.519 1.00 59.30  ? 25  VAL A HG12 1 
ATOM 363  H HG13 . VAL A 1 25  ? 101.175 118.199 114.453 1.00 56.47  ? 25  VAL A HG13 1 
ATOM 364  H HG21 . VAL A 1 25  ? 98.658  120.042 115.536 1.00 58.43  ? 25  VAL A HG21 1 
ATOM 365  H HG22 . VAL A 1 25  ? 98.658  118.715 114.663 1.00 57.95  ? 25  VAL A HG22 1 
ATOM 366  H HG23 . VAL A 1 25  ? 98.044  118.702 116.126 1.00 58.08  ? 25  VAL A HG23 1 
ATOM 367  N N    . VAL A 1 26  ? 101.953 116.979 118.162 1.00 56.50  ? 26  VAL A N    1 
ATOM 368  C CA   . VAL A 1 26  ? 103.347 116.703 118.513 1.00 55.89  ? 26  VAL A CA   1 
ATOM 369  C C    . VAL A 1 26  ? 103.715 115.240 118.299 1.00 55.88  ? 26  VAL A C    1 
ATOM 370  O O    . VAL A 1 26  ? 104.772 114.973 117.703 1.00 61.79  ? 26  VAL A O    1 
ATOM 371  C CB   . VAL A 1 26  ? 103.628 117.179 119.954 1.00 53.88  ? 26  VAL A CB   1 
ATOM 372  C CG1  . VAL A 1 26  ? 104.977 116.671 120.430 1.00 56.31  ? 26  VAL A CG1  1 
ATOM 373  C CG2  . VAL A 1 26  ? 103.573 118.696 120.023 1.00 48.43  ? 26  VAL A CG2  1 
ATOM 374  H H    . VAL A 1 26  ? 101.472 117.279 118.808 1.00 55.47  ? 26  VAL A H    1 
ATOM 375  H HA   . VAL A 1 26  ? 103.914 117.228 117.928 1.00 55.77  ? 26  VAL A HA   1 
ATOM 376  H HB   . VAL A 1 26  ? 102.948 116.836 120.549 1.00 54.31  ? 26  VAL A HB   1 
ATOM 377  H HG11 . VAL A 1 26  ? 105.253 117.193 121.200 1.00 54.73  ? 26  VAL A HG11 1 
ATOM 378  H HG12 . VAL A 1 26  ? 104.897 115.737 120.679 1.00 55.80  ? 26  VAL A HG12 1 
ATOM 379  H HG13 . VAL A 1 26  ? 105.625 116.773 119.716 1.00 56.91  ? 26  VAL A HG13 1 
ATOM 380  H HG21 . VAL A 1 26  ? 103.753 118.977 120.934 1.00 49.32  ? 26  VAL A HG21 1 
ATOM 381  H HG22 . VAL A 1 26  ? 104.242 119.065 119.425 1.00 51.64  ? 26  VAL A HG22 1 
ATOM 382  H HG23 . VAL A 1 26  ? 102.689 118.993 119.754 1.00 52.40  ? 26  VAL A HG23 1 
ATOM 383  N N    . PRO A 1 27  ? 102.925 114.258 118.742 1.00 49.10  ? 27  PRO A N    1 
ATOM 384  C CA   . PRO A 1 27  ? 103.318 112.854 118.529 1.00 49.48  ? 27  PRO A CA   1 
ATOM 385  C C    . PRO A 1 27  ? 103.439 112.462 117.068 1.00 54.30  ? 27  PRO A C    1 
ATOM 386  O O    . PRO A 1 27  ? 104.102 111.461 116.763 1.00 58.44  ? 27  PRO A O    1 
ATOM 387  C CB   . PRO A 1 27  ? 102.199 112.068 119.222 1.00 49.13  ? 27  PRO A CB   1 
ATOM 388  C CG   . PRO A 1 27  ? 101.655 112.997 120.237 1.00 54.37  ? 27  PRO A CG   1 
ATOM 389  C CD   . PRO A 1 27  ? 101.779 114.373 119.660 1.00 53.02  ? 27  PRO A CD   1 
ATOM 390  H HA   . PRO A 1 27  ? 104.157 112.671 118.978 1.00 50.29  ? 27  PRO A HA   1 
ATOM 391  H HB2  . PRO A 1 27  ? 101.520 111.827 118.573 1.00 50.74  ? 27  PRO A HB2  1 
ATOM 392  H HB3  . PRO A 1 27  ? 102.568 111.275 119.643 1.00 50.24  ? 27  PRO A HB3  1 
ATOM 393  H HG2  . PRO A 1 27  ? 100.724 112.785 120.405 1.00 53.95  ? 27  PRO A HG2  1 
ATOM 394  H HG3  . PRO A 1 27  ? 102.174 112.926 121.055 1.00 53.38  ? 27  PRO A HG3  1 
ATOM 395  H HD2  . PRO A 1 27  ? 100.979 114.612 119.171 1.00 53.55  ? 27  PRO A HD2  1 
ATOM 396  H HD3  . PRO A 1 27  ? 101.969 115.004 120.367 1.00 53.14  ? 27  PRO A HD3  1 
ATOM 397  N N    . ILE A 1 28  ? 102.813 113.204 116.153 1.00 53.73  ? 28  ILE A N    1 
ATOM 398  C CA   . ILE A 1 28  ? 102.887 112.845 114.741 1.00 58.95  ? 28  ILE A CA   1 
ATOM 399  C C    . ILE A 1 28  ? 104.312 113.001 114.221 1.00 61.18  ? 28  ILE A C    1 
ATOM 400  O O    . ILE A 1 28  ? 104.758 112.229 113.360 1.00 67.69  ? 28  ILE A O    1 
ATOM 401  C CB   . ILE A 1 28  ? 101.886 113.691 113.934 1.00 61.20  ? 28  ILE A CB   1 
ATOM 402  C CG1  . ILE A 1 28  ? 100.454 113.231 114.221 1.00 57.40  ? 28  ILE A CG1  1 
ATOM 403  C CG2  . ILE A 1 28  ? 102.196 113.608 112.451 1.00 65.35  ? 28  ILE A CG2  1 
ATOM 404  C CD1  . ILE A 1 28  ? 100.040 111.975 113.486 1.00 64.66  ? 28  ILE A CD1  1 
ATOM 405  H H    . ILE A 1 28  ? 102.348 113.908 116.321 1.00 55.71  ? 28  ILE A H    1 
ATOM 406  H HA   . ILE A 1 28  ? 102.634 111.913 114.646 1.00 58.83  ? 28  ILE A HA   1 
ATOM 407  H HB   . ILE A 1 28  ? 101.970 114.617 114.215 1.00 59.64  ? 28  ILE A HB   1 
ATOM 408  H HG12 . ILE A 1 28  ? 100.373 113.053 115.170 1.00 56.49  ? 28  ILE A HG12 1 
ATOM 409  H HG13 . ILE A 1 28  ? 99.841  113.939 113.968 1.00 57.44  ? 28  ILE A HG13 1 
ATOM 410  H HG21 . ILE A 1 28  ? 101.423 113.918 111.955 1.00 63.50  ? 28  ILE A HG21 1 
ATOM 411  H HG22 . ILE A 1 28  ? 102.963 114.167 112.253 1.00 63.80  ? 28  ILE A HG22 1 
ATOM 412  H HG23 . ILE A 1 28  ? 102.389 112.687 112.218 1.00 65.14  ? 28  ILE A HG23 1 
ATOM 413  H HD11 . ILE A 1 28  ? 99.197  111.665 113.851 1.00 61.67  ? 28  ILE A HD11 1 
ATOM 414  H HD12 . ILE A 1 28  ? 99.936  112.178 112.543 1.00 61.03  ? 28  ILE A HD12 1 
ATOM 415  H HD13 . ILE A 1 28  ? 100.718 111.293 113.610 1.00 64.41  ? 28  ILE A HD13 1 
ATOM 416  N N    . MET A 1 29  ? 105.049 113.989 114.731 1.00 55.47  ? 29  MET A N    1 
ATOM 417  C CA   . MET A 1 29  ? 106.443 114.149 114.332 1.00 57.39  ? 29  MET A CA   1 
ATOM 418  C C    . MET A 1 29  ? 107.259 112.927 114.728 1.00 60.52  ? 29  MET A C    1 
ATOM 419  O O    . MET A 1 29  ? 108.062 112.421 113.936 1.00 62.70  ? 29  MET A O    1 
ATOM 420  C CB   . MET A 1 29  ? 107.027 115.405 114.979 1.00 58.37  ? 29  MET A CB   1 
ATOM 421  C CG   . MET A 1 29  ? 106.277 116.692 114.650 1.00 64.91  ? 29  MET A CG   1 
ATOM 422  S SD   . MET A 1 29  ? 106.718 118.148 115.637 1.00 87.81  ? 29  MET A SD   1 
ATOM 423  C CE   . MET A 1 29  ? 107.618 117.460 117.027 1.00 70.15  ? 29  MET A CE   1 
ATOM 424  H H    . MET A 1 29  ? 104.772 114.568 115.302 1.00 58.41  ? 29  MET A H    1 
ATOM 425  H HA   . MET A 1 29  ? 106.484 114.262 113.371 1.00 60.00  ? 29  MET A HA   1 
ATOM 426  H HB2  . MET A 1 29  ? 107.004 115.271 115.937 1.00 59.31  ? 29  MET A HB2  1 
ATOM 427  H HB3  . MET A 1 29  ? 107.943 115.515 114.680 1.00 61.30  ? 29  MET A HB3  1 
ATOM 428  H HG2  . MET A 1 29  ? 106.449 116.914 113.721 1.00 64.13  ? 29  MET A HG2  1 
ATOM 429  H HG3  . MET A 1 29  ? 105.328 116.538 114.776 1.00 62.90  ? 29  MET A HG3  1 
ATOM 430  H HE1  . MET A 1 29  ? 107.907 118.185 117.604 1.00 70.85  ? 29  MET A HE1  1 
ATOM 431  H HE2  . MET A 1 29  ? 107.032 116.863 117.519 1.00 71.35  ? 29  MET A HE2  1 
ATOM 432  H HE3  . MET A 1 29  ? 108.391 116.974 116.699 1.00 72.11  ? 29  MET A HE3  1 
ATOM 433  N N    . TRP A 1 30  ? 107.052 112.430 115.948 1.00 58.48  ? 30  TRP A N    1 
ATOM 434  C CA   . TRP A 1 30  ? 107.751 111.231 116.389 1.00 59.09  ? 30  TRP A CA   1 
ATOM 435  C C    . TRP A 1 30  ? 107.309 110.007 115.600 1.00 59.49  ? 30  TRP A C    1 
ATOM 436  O O    . TRP A 1 30  ? 108.110 109.097 115.377 1.00 64.32  ? 30  TRP A O    1 
ATOM 437  C CB   . TRP A 1 30  ? 107.519 111.018 117.882 1.00 62.84  ? 30  TRP A CB   1 
ATOM 438  C CG   . TRP A 1 30  ? 108.188 112.046 118.738 1.00 60.47  ? 30  TRP A CG   1 
ATOM 439  C CD1  . TRP A 1 30  ? 107.588 113.080 119.395 1.00 62.93  ? 30  TRP A CD1  1 
ATOM 440  C CD2  . TRP A 1 30  ? 109.586 112.140 119.036 1.00 59.15  ? 30  TRP A CD2  1 
ATOM 441  N NE1  . TRP A 1 30  ? 108.525 113.813 120.081 1.00 61.37  ? 30  TRP A NE1  1 
ATOM 442  C CE2  . TRP A 1 30  ? 109.760 113.256 119.877 1.00 62.32  ? 30  TRP A CE2  1 
ATOM 443  C CE3  . TRP A 1 30  ? 110.707 111.389 118.672 1.00 62.87  ? 30  TRP A CE3  1 
ATOM 444  C CZ2  . TRP A 1 30  ? 111.009 113.639 120.362 1.00 66.14  ? 30  TRP A CZ2  1 
ATOM 445  C CZ3  . TRP A 1 30  ? 111.946 111.771 119.153 1.00 59.66  ? 30  TRP A CZ3  1 
ATOM 446  C CH2  . TRP A 1 30  ? 112.087 112.886 119.989 1.00 56.75  ? 30  TRP A CH2  1 
ATOM 447  H H    . TRP A 1 30  ? 106.518 112.767 116.531 1.00 58.98  ? 30  TRP A H    1 
ATOM 448  H HA   . TRP A 1 30  ? 108.703 111.351 116.247 1.00 60.23  ? 30  TRP A HA   1 
ATOM 449  H HB2  . TRP A 1 30  ? 106.566 111.055 118.059 1.00 61.18  ? 30  TRP A HB2  1 
ATOM 450  H HB3  . TRP A 1 30  ? 107.868 110.148 118.133 1.00 62.47  ? 30  TRP A HB3  1 
ATOM 451  H HD1  . TRP A 1 30  ? 106.676 113.263 119.379 1.00 61.94  ? 30  TRP A HD1  1 
ATOM 452  H HE1  . TRP A 1 30  ? 108.363 114.508 120.562 1.00 61.94  ? 30  TRP A HE1  1 
ATOM 453  H HE3  . TRP A 1 30  ? 110.622 110.647 118.118 1.00 62.87  ? 30  TRP A HE3  1 
ATOM 454  H HZ2  . TRP A 1 30  ? 111.105 114.379 120.917 1.00 65.52  ? 30  TRP A HZ2  1 
ATOM 455  H HZ3  . TRP A 1 30  ? 112.699 111.279 118.919 1.00 61.32  ? 30  TRP A HZ3  1 
ATOM 456  H HH2  . TRP A 1 30  ? 112.932 113.118 120.298 1.00 58.42  ? 30  TRP A HH2  1 
ATOM 457  N N    . LEU A 1 31  ? 106.044 109.960 115.179 1.00 56.81  ? 31  LEU A N    1 
ATOM 458  C CA   . LEU A 1 31  ? 105.598 108.858 114.330 1.00 59.79  ? 31  LEU A CA   1 
ATOM 459  C C    . LEU A 1 31  ? 106.333 108.866 112.993 1.00 58.98  ? 31  LEU A C    1 
ATOM 460  O O    . LEU A 1 31  ? 106.773 107.815 112.505 1.00 60.57  ? 31  LEU A O    1 
ATOM 461  C CB   . LEU A 1 31  ? 104.089 108.939 114.112 1.00 48.33  ? 31  LEU A CB   1 
ATOM 462  H H    . LEU A 1 31  ? 105.437 110.541 115.364 1.00 57.36  ? 31  LEU A H    1 
ATOM 463  H HA   . LEU A 1 31  ? 105.794 108.016 114.773 1.00 59.63  ? 31  LEU A HA   1 
ATOM 464  N N    . CYS A 1 32  ? 106.480 110.046 112.386 1.00 57.82  ? 32  CYS A N    1 
ATOM 465  C CA   . CYS A 1 32  ? 107.248 110.141 111.147 1.00 59.81  ? 32  CYS A CA   1 
ATOM 466  C C    . CYS A 1 32  ? 108.704 109.757 111.381 1.00 58.14  ? 32  CYS A C    1 
ATOM 467  O O    . CYS A 1 32  ? 109.329 109.098 110.540 1.00 62.15  ? 32  CYS A O    1 
ATOM 468  C CB   . CYS A 1 32  ? 107.155 111.556 110.576 1.00 61.41  ? 32  CYS A CB   1 
ATOM 469  S SG   . CYS A 1 32  ? 108.486 111.971 109.427 1.00 67.01  ? 32  CYS A SG   1 
ATOM 470  H H    . CYS A 1 32  ? 106.154 110.791 112.666 1.00 59.51  ? 32  CYS A H    1 
ATOM 471  H HA   . CYS A 1 32  ? 106.874 109.530 110.493 1.00 59.47  ? 32  CYS A HA   1 
ATOM 472  H HB2  . CYS A 1 32  ? 106.315 111.650 110.101 1.00 61.50  ? 32  CYS A HB2  1 
ATOM 473  H HB3  . CYS A 1 32  ? 107.191 112.189 111.309 1.00 60.40  ? 32  CYS A HB3  1 
ATOM 474  H HG   . CYS A 1 32  ? 108.319 113.097 109.047 1.00 67.06  ? 32  CYS A HG   1 
ATOM 475  N N    . THR A 1 33  ? 109.261 110.172 112.520 1.00 57.30  ? 33  THR A N    1 
ATOM 476  C CA   . THR A 1 33  ? 110.621 109.784 112.877 1.00 55.96  ? 33  THR A CA   1 
ATOM 477  C C    . THR A 1 33  ? 110.750 108.267 112.964 1.00 58.28  ? 33  THR A C    1 
ATOM 478  O O    . THR A 1 33  ? 111.717 107.686 112.459 1.00 62.72  ? 33  THR A O    1 
ATOM 479  C CB   . THR A 1 33  ? 111.003 110.446 114.205 1.00 57.84  ? 33  THR A CB   1 
ATOM 480  O OG1  . THR A 1 33  ? 111.108 111.862 114.016 1.00 60.96  ? 33  THR A OG1  1 
ATOM 481  C CG2  . THR A 1 33  ? 112.325 109.921 114.752 1.00 59.72  ? 33  THR A CG2  1 
ATOM 482  H H    . THR A 1 33  ? 108.873 110.679 113.097 1.00 59.38  ? 33  THR A H    1 
ATOM 483  H HA   . THR A 1 33  ? 111.233 110.099 112.194 1.00 57.19  ? 33  THR A HA   1 
ATOM 484  H HB   . THR A 1 33  ? 110.311 110.265 114.860 1.00 58.78  ? 33  THR A HB   1 
ATOM 485  H HG1  . THR A 1 33  ? 111.704 112.032 113.449 1.00 60.17  ? 33  THR A HG1  1 
ATOM 486  H HG21 . THR A 1 33  ? 113.057 110.218 114.195 1.00 61.07  ? 33  THR A HG21 1 
ATOM 487  H HG22 . THR A 1 33  ? 112.461 110.270 115.647 1.00 59.73  ? 33  THR A HG22 1 
ATOM 488  H HG23 . THR A 1 33  ? 112.330 108.954 114.798 1.00 59.18  ? 33  THR A HG23 1 
ATOM 489  N N    . GLN A 1 34  ? 109.781 107.609 113.600 1.00 60.10  ? 34  GLN A N    1 
ATOM 490  C CA   . GLN A 1 34  ? 109.806 106.154 113.688 1.00 59.23  ? 34  GLN A CA   1 
ATOM 491  C C    . GLN A 1 34  ? 109.735 105.524 112.305 1.00 60.32  ? 34  GLN A C    1 
ATOM 492  O O    . GLN A 1 34  ? 110.446 104.555 112.017 1.00 61.01  ? 34  GLN A O    1 
ATOM 493  C CB   . GLN A 1 34  ? 108.643 105.663 114.550 1.00 54.18  ? 34  GLN A CB   1 
ATOM 494  C CG   . GLN A 1 34  ? 108.889 104.318 115.209 1.00 62.18  ? 34  GLN A CG   1 
ATOM 495  C CD   . GLN A 1 34  ? 109.167 104.440 116.692 1.00 62.52  ? 34  GLN A CD   1 
ATOM 496  O OE1  . GLN A 1 34  ? 109.764 105.413 117.144 1.00 59.48  ? 34  GLN A OE1  1 
ATOM 497  N NE2  . GLN A 1 34  ? 108.738 103.446 117.459 1.00 61.18  ? 34  GLN A NE2  1 
ATOM 498  H H    . GLN A 1 34  ? 109.109 107.979 113.987 1.00 59.95  ? 34  GLN A H    1 
ATOM 499  H HA   . GLN A 1 34  ? 110.635 105.875 114.107 1.00 59.50  ? 34  GLN A HA   1 
ATOM 500  H HB2  . GLN A 1 34  ? 108.476 106.312 115.252 1.00 56.54  ? 34  GLN A HB2  1 
ATOM 501  H HB3  . GLN A 1 34  ? 107.855 105.575 113.991 1.00 56.84  ? 34  GLN A HB3  1 
ATOM 502  H HG2  . GLN A 1 34  ? 108.105 103.759 115.093 1.00 62.57  ? 34  GLN A HG2  1 
ATOM 503  H HG3  . GLN A 1 34  ? 109.660 103.899 114.794 1.00 62.14  ? 34  GLN A HG3  1 
ATOM 504  H HE21 . GLN A 1 34  ? 108.325 102.780 117.107 1.00 62.65  ? 34  GLN A HE21 1 
ATOM 505  H HE22 . GLN A 1 34  ? 108.873 103.469 118.308 1.00 62.70  ? 34  GLN A HE22 1 
ATOM 506  N N    . SER A 1 35  ? 108.877 106.061 111.437 1.00 59.07  ? 35  SER A N    1 
ATOM 507  C CA   . SER A 1 35  ? 108.731 105.495 110.099 1.00 61.59  ? 35  SER A CA   1 
ATOM 508  C C    . SER A 1 35  ? 110.015 105.635 109.288 1.00 58.60  ? 35  SER A C    1 
ATOM 509  O O    . SER A 1 35  ? 110.386 104.719 108.545 1.00 54.82  ? 35  SER A O    1 
ATOM 510  C CB   . SER A 1 35  ? 107.566 106.164 109.372 1.00 64.97  ? 35  SER A CB   1 
ATOM 511  O OG   . SER A 1 35  ? 106.326 105.792 109.946 1.00 64.17  ? 35  SER A OG   1 
ATOM 512  H H    . SER A 1 35  ? 108.377 106.742 111.594 1.00 59.70  ? 35  SER A H    1 
ATOM 513  H HA   . SER A 1 35  ? 108.531 104.548 110.179 1.00 61.53  ? 35  SER A HA   1 
ATOM 514  H HB2  . SER A 1 35  ? 107.666 107.126 109.438 1.00 62.59  ? 35  SER A HB2  1 
ATOM 515  H HB3  . SER A 1 35  ? 107.578 105.895 108.440 1.00 62.34  ? 35  SER A HB3  1 
ATOM 516  H HG   . SER A 1 35  ? 105.695 106.049 109.456 1.00 62.58  ? 35  SER A HG   1 
ATOM 517  N N    . MET A 1 36  ? 110.701 106.770 109.408 1.00 63.18  ? 36  MET A N    1 
ATOM 518  C CA   . MET A 1 36  ? 111.885 107.052 108.604 1.00 65.41  ? 36  MET A CA   1 
ATOM 519  C C    . MET A 1 36  ? 113.190 106.681 109.302 1.00 60.38  ? 36  MET A C    1 
ATOM 520  O O    . MET A 1 36  ? 114.265 106.939 108.751 1.00 59.86  ? 36  MET A O    1 
ATOM 521  C CB   . MET A 1 36  ? 111.908 108.536 108.216 1.00 58.52  ? 36  MET A CB   1 
ATOM 522  C CG   . MET A 1 36  ? 112.057 108.817 106.717 1.00 59.15  ? 36  MET A CG   1 
ATOM 523  S SD   . MET A 1 36  ? 111.071 107.761 105.631 1.00 83.77  ? 36  MET A SD   1 
ATOM 524  C CE   . MET A 1 36  ? 109.473 108.557 105.730 1.00 72.39  ? 36  MET A CE   1 
ATOM 525  H H    . MET A 1 36  ? 110.499 107.401 109.956 1.00 62.06  ? 36  MET A H    1 
ATOM 526  H HA   . MET A 1 36  ? 111.832 106.525 107.795 1.00 65.37  ? 36  MET A HA   1 
ATOM 527  H HB2  . MET A 1 36  ? 111.076 108.941 108.506 1.00 61.02  ? 36  MET A HB2  1 
ATOM 528  H HB3  . MET A 1 36  ? 112.652 108.963 108.669 1.00 58.31  ? 36  MET A HB3  1 
ATOM 529  H HG2  . MET A 1 36  ? 111.790 109.734 106.550 1.00 62.18  ? 36  MET A HG2  1 
ATOM 530  H HG3  . MET A 1 36  ? 112.988 108.701 106.472 1.00 60.67  ? 36  MET A HG3  1 
ATOM 531  H HE1  . MET A 1 36  ? 108.823 108.019 105.250 1.00 71.37  ? 36  MET A HE1  1 
ATOM 532  H HE2  . MET A 1 36  ? 109.216 108.635 106.661 1.00 69.02  ? 36  MET A HE2  1 
ATOM 533  H HE3  . MET A 1 36  ? 109.536 109.436 105.327 1.00 73.36  ? 36  MET A HE3  1 
ATOM 534  N N    . LEU A 1 37  ? 113.123 106.083 110.493 1.00 61.20  ? 37  LEU A N    1 
ATOM 535  C CA   . LEU A 1 37  ? 114.333 105.670 111.197 1.00 60.61  ? 37  LEU A CA   1 
ATOM 536  C C    . LEU A 1 37  ? 115.164 104.665 110.410 1.00 60.27  ? 37  LEU A C    1 
ATOM 537  O O    . LEU A 1 37  ? 116.361 104.517 110.688 1.00 58.14  ? 37  LEU A O    1 
ATOM 538  C CB   . LEU A 1 37  ? 113.945 105.083 112.556 1.00 60.17  ? 37  LEU A CB   1 
ATOM 539  C CG   . LEU A 1 37  ? 115.064 104.564 113.456 1.00 60.54  ? 37  LEU A CG   1 
ATOM 540  C CD1  . LEU A 1 37  ? 114.808 104.967 114.893 1.00 57.24  ? 37  LEU A CD1  1 
ATOM 541  C CD2  . LEU A 1 37  ? 115.167 103.054 113.344 1.00 62.15  ? 37  LEU A CD2  1 
ATOM 542  H H    . LEU A 1 37  ? 112.393 105.904 110.912 1.00 60.99  ? 37  LEU A H    1 
ATOM 543  H HA   . LEU A 1 37  ? 114.883 106.449 111.359 1.00 60.03  ? 37  LEU A HA   1 
ATOM 544  H HB2  . LEU A 1 37  ? 113.477 105.771 113.055 1.00 60.50  ? 37  LEU A HB2  1 
ATOM 545  H HB3  . LEU A 1 37  ? 113.341 104.341 112.399 1.00 60.04  ? 37  LEU A HB3  1 
ATOM 546  H HG   . LEU A 1 37  ? 115.909 104.949 113.175 1.00 60.40  ? 37  LEU A HG   1 
ATOM 547  H HD11 . LEU A 1 37  ? 113.979 104.561 115.192 1.00 59.32  ? 37  LEU A HD11 1 
ATOM 548  H HD12 . LEU A 1 37  ? 115.545 104.658 115.444 1.00 58.89  ? 37  LEU A HD12 1 
ATOM 549  H HD13 . LEU A 1 37  ? 114.740 105.933 114.942 1.00 57.12  ? 37  LEU A HD13 1 
ATOM 550  H HD21 . LEU A 1 37  ? 115.863 102.740 113.942 1.00 61.86  ? 37  LEU A HD21 1 
ATOM 551  H HD22 . LEU A 1 37  ? 114.316 102.661 113.592 1.00 61.42  ? 37  LEU A HD22 1 
ATOM 552  H HD23 . LEU A 1 37  ? 115.386 102.819 112.429 1.00 62.15  ? 37  LEU A HD23 1 
ATOM 553  N N    . GLU A 1 38  ? 114.565 103.981 109.434 1.00 62.21  ? 38  GLU A N    1 
ATOM 554  C CA   . GLU A 1 38  ? 115.273 102.916 108.730 1.00 61.58  ? 38  GLU A CA   1 
ATOM 555  C C    . GLU A 1 38  ? 116.462 103.455 107.943 1.00 59.12  ? 38  GLU A C    1 
ATOM 556  O O    . GLU A 1 38  ? 117.495 102.786 107.834 1.00 57.75  ? 38  GLU A O    1 
ATOM 557  C CB   . GLU A 1 38  ? 114.310 102.179 107.803 1.00 66.49  ? 38  GLU A CB   1 
ATOM 558  C CG   . GLU A 1 38  ? 114.413 100.670 107.891 1.00 67.64  ? 38  GLU A CG   1 
ATOM 559  C CD   . GLU A 1 38  ? 113.684 100.100 109.092 1.00 68.97  ? 38  GLU A CD   1 
ATOM 560  O OE1  . GLU A 1 38  ? 112.450 100.270 109.176 1.00 71.14  ? 38  GLU A OE1  1 
ATOM 561  O OE2  . GLU A 1 38  ? 114.345 99.478  109.950 1.00 61.83  ? 38  GLU A OE2  1 
ATOM 562  H H    . GLU A 1 38  ? 113.760 104.115 109.164 1.00 61.75  ? 38  GLU A H    1 
ATOM 563  H HA   . GLU A 1 38  ? 115.610 102.279 109.379 1.00 61.73  ? 38  GLU A HA   1 
ATOM 564  H HB2  . GLU A 1 38  ? 113.400 102.427 108.031 1.00 65.59  ? 38  GLU A HB2  1 
ATOM 565  H HB3  . GLU A 1 38  ? 114.500 102.437 106.887 1.00 64.75  ? 38  GLU A HB3  1 
ATOM 566  H HG2  . GLU A 1 38  ? 114.019 100.287 107.094 1.00 66.96  ? 38  GLU A HG2  1 
ATOM 567  H HG3  . GLU A 1 38  ? 115.347 100.417 107.957 1.00 64.77  ? 38  GLU A HG3  1 
ATOM 568  N N    . ASN A 1 39  ? 116.334 104.657 107.376 1.00 60.02  ? 39  ASN A N    1 
ATOM 569  C CA   . ASN A 1 39  ? 117.414 105.200 106.557 1.00 60.18  ? 39  ASN A CA   1 
ATOM 570  C C    . ASN A 1 39  ? 118.720 105.288 107.334 1.00 58.81  ? 39  ASN A C    1 
ATOM 571  O O    . ASN A 1 39  ? 119.800 105.176 106.744 1.00 57.20  ? 39  ASN A O    1 
ATOM 572  C CB   . ASN A 1 39  ? 117.030 106.582 106.030 1.00 62.13  ? 39  ASN A CB   1 
ATOM 573  C CG   . ASN A 1 39  ? 115.756 106.563 105.216 1.00 61.12  ? 39  ASN A CG   1 
ATOM 574  O OD1  . ASN A 1 39  ? 115.396 105.545 104.630 1.00 62.96  ? 39  ASN A OD1  1 
ATOM 575  N ND2  . ASN A 1 39  ? 115.061 107.693 105.179 1.00 58.54  ? 39  ASN A ND2  1 
ATOM 576  H H    . ASN A 1 39  ? 115.647 105.168 107.450 1.00 60.72  ? 39  ASN A H    1 
ATOM 577  H HA   . ASN A 1 39  ? 117.557 104.617 105.795 1.00 60.85  ? 39  ASN A HA   1 
ATOM 578  H HB2  . ASN A 1 39  ? 116.899 107.182 106.781 1.00 61.83  ? 39  ASN A HB2  1 
ATOM 579  H HB3  . ASN A 1 39  ? 117.744 106.913 105.463 1.00 61.44  ? 39  ASN A HB3  1 
ATOM 580  H HD21 . ASN A 1 39  ? 115.344 108.385 105.603 1.00 59.58  ? 39  ASN A HD21 1 
ATOM 581  H HD22 . ASN A 1 39  ? 114.329 107.733 104.730 1.00 61.03  ? 39  ASN A HD22 1 
ATOM 582  N N    . PHE A 1 40  ? 118.643 105.485 108.648 1.00 61.89  ? 40  PHE A N    1 
ATOM 583  C CA   . PHE A 1 40  ? 119.818 105.686 109.484 1.00 58.29  ? 40  PHE A CA   1 
ATOM 584  C C    . PHE A 1 40  ? 120.166 104.494 110.357 1.00 55.93  ? 40  PHE A C    1 
ATOM 585  O O    . PHE A 1 40  ? 121.347 104.274 110.629 1.00 54.78  ? 40  PHE A O    1 
ATOM 586  C CB   . PHE A 1 40  ? 119.618 106.911 110.381 1.00 57.03  ? 40  PHE A CB   1 
ATOM 587  C CG   . PHE A 1 40  ? 119.301 108.159 109.622 1.00 53.84  ? 40  PHE A CG   1 
ATOM 588  C CD1  . PHE A 1 40  ? 120.317 108.944 109.110 1.00 55.51  ? 40  PHE A CD1  1 
ATOM 589  C CD2  . PHE A 1 40  ? 117.989 108.532 109.391 1.00 55.99  ? 40  PHE A CD2  1 
ATOM 590  C CE1  . PHE A 1 40  ? 120.033 110.089 108.402 1.00 56.77  ? 40  PHE A CE1  1 
ATOM 591  C CE2  . PHE A 1 40  ? 117.700 109.677 108.681 1.00 59.56  ? 40  PHE A CE2  1 
ATOM 592  C CZ   . PHE A 1 40  ? 118.722 110.455 108.187 1.00 58.33  ? 40  PHE A CZ   1 
ATOM 593  H H    . PHE A 1 40  ? 117.903 105.507 109.087 1.00 60.21  ? 40  PHE A H    1 
ATOM 594  H HA   . PHE A 1 40  ? 120.583 105.864 108.913 1.00 57.59  ? 40  PHE A HA   1 
ATOM 595  H HB2  . PHE A 1 40  ? 118.880 106.737 110.985 1.00 57.94  ? 40  PHE A HB2  1 
ATOM 596  H HB3  . PHE A 1 40  ? 120.433 107.068 110.884 1.00 56.88  ? 40  PHE A HB3  1 
ATOM 597  H HD1  . PHE A 1 40  ? 121.203 108.701 109.257 1.00 56.79  ? 40  PHE A HD1  1 
ATOM 598  H HD2  . PHE A 1 40  ? 117.296 108.009 109.725 1.00 57.42  ? 40  PHE A HD2  1 
ATOM 599  H HE1  . PHE A 1 40  ? 120.724 110.615 108.068 1.00 57.15  ? 40  PHE A HE1  1 
ATOM 600  H HE2  . PHE A 1 40  ? 116.816 109.926 108.533 1.00 59.97  ? 40  PHE A HE2  1 
ATOM 601  H HZ   . PHE A 1 40  ? 118.528 111.227 107.708 1.00 57.98  ? 40  PHE A HZ   1 
ATOM 602  N N    . SER A 1 41  ? 119.180 103.720 110.801 1.00 55.08  ? 41  SER A N    1 
ATOM 603  C CA   . SER A 1 41  ? 119.448 102.555 111.631 1.00 53.41  ? 41  SER A CA   1 
ATOM 604  C C    . SER A 1 41  ? 119.694 101.296 110.812 1.00 58.29  ? 41  SER A C    1 
ATOM 605  O O    . SER A 1 41  ? 119.920 100.231 111.394 1.00 63.07  ? 41  SER A O    1 
ATOM 606  C CB   . SER A 1 41  ? 118.286 102.321 112.598 1.00 55.09  ? 41  SER A CB   1 
ATOM 607  O OG   . SER A 1 41  ? 117.391 101.347 112.094 1.00 64.53  ? 41  SER A OG   1 
ATOM 608  H H    . SER A 1 41  ? 118.346 103.849 110.634 1.00 57.17  ? 41  SER A H    1 
ATOM 609  H HA   . SER A 1 41  ? 120.244 102.724 112.159 1.00 54.25  ? 41  SER A HA   1 
ATOM 610  H HB2  . SER A 1 41  ? 118.639 102.017 113.449 1.00 55.31  ? 41  SER A HB2  1 
ATOM 611  H HB3  . SER A 1 41  ? 117.809 103.157 112.718 1.00 57.34  ? 41  SER A HB3  1 
ATOM 612  H HG   . SER A 1 41  ? 116.815 101.158 112.675 1.00 62.32  ? 41  SER A HG   1 
ATOM 613  N N    . ALA A 1 42  ? 119.662 101.393 109.480 1.00 60.41  ? 42  ALA A N    1 
ATOM 614  C CA   . ALA A 1 42  ? 119.903 100.248 108.613 1.00 58.79  ? 42  ALA A CA   1 
ATOM 615  C C    . ALA A 1 42  ? 120.799 100.623 107.439 1.00 58.58  ? 42  ALA A C    1 
ATOM 616  O O    . ALA A 1 42  ? 120.642 100.087 106.339 1.00 60.00  ? 42  ALA A O    1 
ATOM 617  C CB   . ALA A 1 42  ? 118.587 99.663  108.095 1.00 55.96  ? 42  ALA A CB   1 
ATOM 618  H H    . ALA A 1 42  ? 119.502 102.121 109.052 1.00 59.40  ? 42  ALA A H    1 
ATOM 619  H HA   . ALA A 1 42  ? 120.355 99.556  109.120 1.00 59.30  ? 42  ALA A HA   1 
ATOM 620  H HB1  . ALA A 1 42  ? 118.125 100.339 107.574 1.00 57.78  ? 42  ALA A HB1  1 
ATOM 621  H HB2  . ALA A 1 42  ? 118.781 98.892  107.540 1.00 56.69  ? 42  ALA A HB2  1 
ATOM 622  H HB3  . ALA A 1 42  ? 118.041 99.397  108.852 1.00 56.70  ? 42  ALA A HB3  1 
ATOM 623  N N    . ALA A 1 43  ? 121.737 101.539 107.649 1.00 55.83  ? 43  ALA A N    1 
ATOM 624  C CA   . ALA A 1 43  ? 122.648 101.923 106.582 1.00 54.16  ? 43  ALA A CA   1 
ATOM 625  C C    . ALA A 1 43  ? 123.561 100.760 106.214 1.00 57.20  ? 43  ALA A C    1 
ATOM 626  O O    . ALA A 1 43  ? 123.862 99.891  107.036 1.00 56.04  ? 43  ALA A O    1 
ATOM 627  C CB   . ALA A 1 43  ? 123.485 103.130 107.000 1.00 51.67  ? 43  ALA A CB   1 
ATOM 628  H H    . ALA A 1 43  ? 121.867 101.949 108.393 1.00 56.34  ? 43  ALA A H    1 
ATOM 629  H HA   . ALA A 1 43  ? 122.135 102.167 105.796 1.00 55.26  ? 43  ALA A HA   1 
ATOM 630  H HB1  . ALA A 1 43  ? 124.080 103.367 106.272 1.00 53.61  ? 43  ALA A HB1  1 
ATOM 631  H HB2  . ALA A 1 43  ? 122.892 103.872 107.199 1.00 54.25  ? 43  ALA A HB2  1 
ATOM 632  H HB3  . ALA A 1 43  ? 124.001 102.896 107.787 1.00 53.09  ? 43  ALA A HB3  1 
ATOM 633  N N    . VAL A 1 44  ? 124.002 100.752 104.961 1.00 56.07  ? 44  VAL A N    1 
ATOM 634  C CA   . VAL A 1 44  ? 124.897 99.714  104.456 1.00 55.06  ? 44  VAL A CA   1 
ATOM 635  C C    . VAL A 1 44  ? 126.266 100.346 104.232 1.00 52.96  ? 44  VAL A C    1 
ATOM 636  O O    . VAL A 1 44  ? 126.451 101.080 103.251 1.00 60.05  ? 44  VAL A O    1 
ATOM 637  C CB   . VAL A 1 44  ? 124.350 99.083  103.165 1.00 59.36  ? 44  VAL A CB   1 
ATOM 638  C CG1  . VAL A 1 44  ? 125.482 98.534  102.298 1.00 56.15  ? 44  VAL A CG1  1 
ATOM 639  C CG2  . VAL A 1 44  ? 123.348 97.985  103.490 1.00 59.37  ? 44  VAL A CG2  1 
ATOM 640  H H    . VAL A 1 44  ? 123.793 101.344 104.373 1.00 56.56  ? 44  VAL A H    1 
ATOM 641  H HA   . VAL A 1 44  ? 124.976 99.007  105.114 1.00 56.45  ? 44  VAL A HA   1 
ATOM 642  H HB   . VAL A 1 44  ? 123.888 99.765  102.653 1.00 58.59  ? 44  VAL A HB   1 
ATOM 643  H HG11 . VAL A 1 44  ? 125.107 97.907  101.659 1.00 58.31  ? 44  VAL A HG11 1 
ATOM 644  H HG12 . VAL A 1 44  ? 125.909 99.264  101.823 1.00 55.50  ? 44  VAL A HG12 1 
ATOM 645  H HG13 . VAL A 1 44  ? 126.125 98.077  102.862 1.00 55.38  ? 44  VAL A HG13 1 
ATOM 646  H HG21 . VAL A 1 44  ? 123.009 97.612  102.661 1.00 58.69  ? 44  VAL A HG21 1 
ATOM 647  H HG22 . VAL A 1 44  ? 123.794 97.294  104.005 1.00 58.70  ? 44  VAL A HG22 1 
ATOM 648  H HG23 . VAL A 1 44  ? 122.618 98.364  104.005 1.00 57.54  ? 44  VAL A HG23 1 
ATOM 649  N N    . PRO A 1 45  ? 127.243 100.115 105.106 1.00 46.06  ? 45  PRO A N    1 
ATOM 650  C CA   . PRO A 1 45  ? 128.596 100.614 104.858 1.00 47.05  ? 45  PRO A CA   1 
ATOM 651  C C    . PRO A 1 45  ? 129.425 99.623  104.053 1.00 48.81  ? 45  PRO A C    1 
ATOM 652  O O    . PRO A 1 45  ? 129.082 98.448  103.911 1.00 54.80  ? 45  PRO A O    1 
ATOM 653  C CB   . PRO A 1 45  ? 129.177 100.795 106.270 1.00 50.45  ? 45  PRO A CB   1 
ATOM 654  C CG   . PRO A 1 45  ? 128.226 100.096 107.215 1.00 48.04  ? 45  PRO A CG   1 
ATOM 655  C CD   . PRO A 1 45  ? 127.143 99.448  106.413 1.00 50.61  ? 45  PRO A CD   1 
ATOM 656  H HA   . PRO A 1 45  ? 128.571 101.472 104.404 1.00 48.94  ? 45  PRO A HA   1 
ATOM 657  H HB2  . PRO A 1 45  ? 130.057 100.389 106.312 1.00 50.29  ? 45  PRO A HB2  1 
ATOM 658  H HB3  . PRO A 1 45  ? 129.229 101.741 106.479 1.00 50.49  ? 45  PRO A HB3  1 
ATOM 659  H HG2  . PRO A 1 45  ? 128.716 99.425  107.717 1.00 48.41  ? 45  PRO A HG2  1 
ATOM 660  H HG3  . PRO A 1 45  ? 127.845 100.751 107.821 1.00 48.72  ? 45  PRO A HG3  1 
ATOM 661  H HD2  . PRO A 1 45  ? 127.307 98.496  106.323 1.00 52.18  ? 45  PRO A HD2  1 
ATOM 662  H HD3  . PRO A 1 45  ? 126.281 99.624  106.820 1.00 52.28  ? 45  PRO A HD3  1 
ATOM 663  N N    . SER A 1 46  ? 130.534 100.129 103.518 1.00 44.30  ? 46  SER A N    1 
ATOM 664  C CA   . SER A 1 46  ? 131.448 99.276  102.771 1.00 46.29  ? 46  SER A CA   1 
ATOM 665  C C    . SER A 1 46  ? 131.917 98.126  103.652 1.00 47.92  ? 46  SER A C    1 
ATOM 666  O O    . SER A 1 46  ? 132.382 98.339  104.775 1.00 54.33  ? 46  SER A O    1 
ATOM 667  C CB   . SER A 1 46  ? 132.642 100.091 102.276 1.00 48.92  ? 46  SER A CB   1 
ATOM 668  O OG   . SER A 1 46  ? 133.564 100.336 103.324 1.00 53.58  ? 46  SER A OG   1 
ATOM 669  H H    . SER A 1 46  ? 130.777 100.952 103.573 1.00 46.71  ? 46  SER A H    1 
ATOM 670  H HA   . SER A 1 46  ? 130.989 98.906  102.001 1.00 47.09  ? 46  SER A HA   1 
ATOM 671  H HB2  . SER A 1 46  ? 133.091 99.597  101.572 1.00 48.98  ? 46  SER A HB2  1 
ATOM 672  H HB3  . SER A 1 46  ? 132.323 100.940 101.933 1.00 49.69  ? 46  SER A HB3  1 
ATOM 673  H HG   . SER A 1 46  ? 133.970 99.628  103.523 1.00 51.87  ? 46  SER A HG   1 
ATOM 674  N N    . HIS A 1 47  ? 131.802 96.902  103.136 1.00 40.27  ? 47  HIS A N    1 
ATOM 675  C CA   . HIS A 1 47  ? 132.087 95.687  103.901 1.00 40.47  ? 47  HIS A CA   1 
ATOM 676  C C    . HIS A 1 47  ? 133.123 94.855  103.152 1.00 39.84  ? 47  HIS A C    1 
ATOM 677  O O    . HIS A 1 47  ? 132.785 94.067  102.264 1.00 44.09  ? 47  HIS A O    1 
ATOM 678  C CB   . HIS A 1 47  ? 130.808 94.896  104.160 1.00 46.48  ? 47  HIS A CB   1 
ATOM 679  C CG   . HIS A 1 47  ? 129.818 94.960  103.040 1.00 47.43  ? 47  HIS A CG   1 
ATOM 680  N ND1  . HIS A 1 47  ? 128.925 95.999  102.898 1.00 51.18  ? 47  HIS A ND1  1 
ATOM 681  C CD2  . HIS A 1 47  ? 129.572 94.109  102.016 1.00 51.65  ? 47  HIS A CD2  1 
ATOM 682  C CE1  . HIS A 1 47  ? 128.174 95.789  101.831 1.00 52.27  ? 47  HIS A CE1  1 
ATOM 683  N NE2  . HIS A 1 47  ? 128.547 94.648  101.278 1.00 56.84  ? 47  HIS A NE2  1 
ATOM 684  H H    . HIS A 1 47  ? 131.559 96.747  102.325 1.00 44.71  ? 47  HIS A H    1 
ATOM 685  H HA   . HIS A 1 47  ? 132.465 95.932  104.760 1.00 44.27  ? 47  HIS A HA   1 
ATOM 686  H HB2  . HIS A 1 47  ? 131.040 93.964  104.296 1.00 46.30  ? 47  HIS A HB2  1 
ATOM 687  H HB3  . HIS A 1 47  ? 130.378 95.247  104.955 1.00 47.65  ? 47  HIS A HB3  1 
ATOM 688  H HD1  . HIS A 1 47  ? 128.866 96.680  103.420 1.00 50.42  ? 47  HIS A HD1  1 
ATOM 689  H HD2  . HIS A 1 47  ? 130.015 93.310  101.843 1.00 49.08  ? 47  HIS A HD2  1 
ATOM 690  H HE1  . HIS A 1 47  ? 127.499 96.348  101.522 1.00 52.14  ? 47  HIS A HE1  1 
ATOM 691  N N    . ARG A 1 48  ? 134.386 95.037  103.521 1.00 45.44  ? 48  ARG A N    1 
ATOM 692  C CA   . ARG A 1 48  ? 135.463 94.202  103.016 1.00 45.05  ? 48  ARG A CA   1 
ATOM 693  C C    . ARG A 1 48  ? 135.424 92.832  103.691 1.00 46.66  ? 48  ARG A C    1 
ATOM 694  O O    . ARG A 1 48  ? 134.810 92.645  104.744 1.00 48.88  ? 48  ARG A O    1 
ATOM 695  C CB   . ARG A 1 48  ? 136.809 94.888  103.265 1.00 53.77  ? 48  ARG A CB   1 
ATOM 696  C CG   . ARG A 1 48  ? 138.030 94.154  102.734 1.00 53.27  ? 48  ARG A CG   1 
ATOM 697  C CD   . ARG A 1 48  ? 139.308 94.865  103.144 1.00 54.12  ? 48  ARG A CD   1 
ATOM 698  N NE   . ARG A 1 48  ? 139.433 94.957  104.595 1.00 47.34  ? 48  ARG A NE   1 
ATOM 699  C CZ   . ARG A 1 48  ? 140.279 94.251  105.335 1.00 50.82  ? 48  ARG A CZ   1 
ATOM 700  N NH1  . ARG A 1 48  ? 141.102 93.364  104.797 1.00 57.63  ? 48  ARG A NH1  1 
ATOM 701  N NH2  . ARG A 1 48  ? 140.297 94.435  106.652 1.00 51.90  ? 48  ARG A NH2  1 
ATOM 702  H H    . ARG A 1 48  ? 134.647 95.646  104.069 1.00 47.18  ? 48  ARG A H    1 
ATOM 703  H HA   . ARG A 1 48  ? 135.355 94.076  102.060 1.00 44.24  ? 48  ARG A HA   1 
ATOM 704  H HB2  . ARG A 1 48  ? 136.790 95.761  102.843 1.00 52.72  ? 48  ARG A HB2  1 
ATOM 705  H HB3  . ARG A 1 48  ? 136.923 94.993  104.222 1.00 50.88  ? 48  ARG A HB3  1 
ATOM 706  H HG2  . ARG A 1 48  ? 138.064 93.259  103.102 1.00 51.02  ? 48  ARG A HG2  1 
ATOM 707  H HG3  . ARG A 1 48  ? 137.993 94.122  101.765 1.00 52.05  ? 48  ARG A HG3  1 
ATOM 708  H HD2  . ARG A 1 48  ? 140.069 94.389  102.782 1.00 52.64  ? 48  ARG A HD2  1 
ATOM 709  H HD3  . ARG A 1 48  ? 139.288 95.769  102.790 1.00 52.97  ? 48  ARG A HD3  1 
ATOM 710  H HE   . ARG A 1 48  ? 138.915 95.509  105.003 1.00 47.84  ? 48  ARG A HE   1 
ATOM 711  H HH11 . ARG A 1 48  ? 141.106 93.229  103.949 1.00 55.19  ? 48  ARG A HH11 1 
ATOM 712  H HH12 . ARG A 1 48  ? 141.638 92.920  105.302 1.00 55.32  ? 48  ARG A HH12 1 
ATOM 713  H HH21 . ARG A 1 48  ? 139.767 95.007  107.013 1.00 52.16  ? 48  ARG A HH21 1 
ATOM 714  H HH22 . ARG A 1 48  ? 140.840 93.982  107.141 1.00 51.01  ? 48  ARG A HH22 1 
ATOM 715  N N    . CYS A 1 49  ? 136.085 91.862  103.065 1.00 50.20  ? 49  CYS A N    1 
ATOM 716  C CA   . CYS A 1 49  ? 136.209 90.534  103.649 1.00 52.73  ? 49  CYS A CA   1 
ATOM 717  C C    . CYS A 1 49  ? 137.347 90.498  104.661 1.00 55.09  ? 49  CYS A C    1 
ATOM 718  O O    . CYS A 1 49  ? 138.431 91.038  104.420 1.00 59.88  ? 49  CYS A O    1 
ATOM 719  C CB   . CYS A 1 49  ? 136.452 89.492  102.558 1.00 60.38  ? 49  CYS A CB   1 
ATOM 720  S SG   . CYS A 1 49  ? 135.899 87.829  102.988 1.00 71.57  ? 49  CYS A SG   1 
ATOM 721  H H    . CYS A 1 49  ? 136.471 91.949  102.301 1.00 50.32  ? 49  CYS A H    1 
ATOM 722  H HA   . CYS A 1 49  ? 135.385 90.307  104.108 1.00 51.88  ? 49  CYS A HA   1 
ATOM 723  H HB2  . CYS A 1 49  ? 135.979 89.763  101.757 1.00 58.82  ? 49  CYS A HB2  1 
ATOM 724  H HB3  . CYS A 1 49  ? 137.405 89.449  102.378 1.00 59.00  ? 49  CYS A HB3  1 
ATOM 725  N N    . TRP A 1 50  ? 137.092 89.858  105.799 1.00 54.66  ? 50  TRP A N    1 
ATOM 726  C CA   . TRP A 1 50  ? 138.119 89.699  106.820 1.00 57.53  ? 50  TRP A CA   1 
ATOM 727  C C    . TRP A 1 50  ? 139.314 88.933  106.263 1.00 58.41  ? 50  TRP A C    1 
ATOM 728  O O    . TRP A 1 50  ? 139.158 87.921  105.574 1.00 59.42  ? 50  TRP A O    1 
ATOM 729  C CB   . TRP A 1 50  ? 137.539 88.962  108.028 1.00 57.73  ? 50  TRP A CB   1 
ATOM 730  C CG   . TRP A 1 50  ? 138.259 89.219  109.314 1.00 56.89  ? 50  TRP A CG   1 
ATOM 731  C CD1  . TRP A 1 50  ? 137.974 90.182  110.237 1.00 51.82  ? 50  TRP A CD1  1 
ATOM 732  C CD2  . TRP A 1 50  ? 139.382 88.493  109.825 1.00 58.18  ? 50  TRP A CD2  1 
ATOM 733  N NE1  . TRP A 1 50  ? 138.851 90.102  111.290 1.00 50.45  ? 50  TRP A NE1  1 
ATOM 734  C CE2  . TRP A 1 50  ? 139.727 89.074  111.062 1.00 55.38  ? 50  TRP A CE2  1 
ATOM 735  C CE3  . TRP A 1 50  ? 140.132 87.410  109.357 1.00 56.53  ? 50  TRP A CE3  1 
ATOM 736  C CZ2  . TRP A 1 50  ? 140.788 88.608  111.835 1.00 57.18  ? 50  TRP A CZ2  1 
ATOM 737  C CZ3  . TRP A 1 50  ? 141.184 86.950  110.125 1.00 53.59  ? 50  TRP A CZ3  1 
ATOM 738  C CH2  . TRP A 1 50  ? 141.502 87.548  111.350 1.00 55.61  ? 50  TRP A CH2  1 
ATOM 739  H H    . TRP A 1 50  ? 136.333 89.509  106.004 1.00 55.40  ? 50  TRP A H    1 
ATOM 740  H HA   . TRP A 1 50  ? 138.423 90.573  107.110 1.00 55.64  ? 50  TRP A HA   1 
ATOM 741  H HB2  . TRP A 1 50  ? 136.618 89.242  108.150 1.00 56.07  ? 50  TRP A HB2  1 
ATOM 742  H HB3  . TRP A 1 50  ? 137.573 88.008  107.857 1.00 57.04  ? 50  TRP A HB3  1 
ATOM 743  H HD1  . TRP A 1 50  ? 137.284 90.801  110.164 1.00 52.91  ? 50  TRP A HD1  1 
ATOM 744  H HE1  . TRP A 1 50  ? 138.851 90.615  111.981 1.00 51.91  ? 50  TRP A HE1  1 
ATOM 745  H HE3  . TRP A 1 50  ? 139.927 87.008  108.544 1.00 56.04  ? 50  TRP A HE3  1 
ATOM 746  H HZ2  . TRP A 1 50  ? 141.002 89.004  112.649 1.00 55.21  ? 50  TRP A HZ2  1 
ATOM 747  H HZ3  . TRP A 1 50  ? 141.689 86.230  109.823 1.00 51.79  ? 50  TRP A HZ3  1 
ATOM 748  H HH2  . TRP A 1 50  ? 142.216 87.217  111.846 1.00 53.74  ? 50  TRP A HH2  1 
ATOM 749  N N    . VAL A 1 51  ? 140.513 89.424  106.565 1.00 56.36  ? 51  VAL A N    1 
ATOM 750  C CA   . VAL A 1 51  ? 141.755 88.798  106.114 1.00 60.38  ? 51  VAL A CA   1 
ATOM 751  C C    . VAL A 1 51  ? 142.713 88.681  107.295 1.00 66.18  ? 51  VAL A C    1 
ATOM 752  O O    . VAL A 1 51  ? 142.933 89.672  108.005 1.00 69.87  ? 51  VAL A O    1 
ATOM 753  C CB   . VAL A 1 51  ? 142.399 89.591  104.966 1.00 66.34  ? 51  VAL A CB   1 
ATOM 754  C CG1  . VAL A 1 51  ? 143.347 88.702  104.173 1.00 69.22  ? 51  VAL A CG1  1 
ATOM 755  C CG2  . VAL A 1 51  ? 141.331 90.168  104.050 1.00 62.59  ? 51  VAL A CG2  1 
ATOM 756  H H    . VAL A 1 51  ? 140.636 90.132  107.038 1.00 57.99  ? 51  VAL A H    1 
ATOM 757  H HA   . VAL A 1 51  ? 141.551 87.915  105.774 1.00 60.17  ? 51  VAL A HA   1 
ATOM 758  H HB   . VAL A 1 51  ? 142.910 90.330  105.333 1.00 65.32  ? 51  VAL A HB   1 
ATOM 759  H HG11 . VAL A 1 51  ? 144.020 89.259  103.752 1.00 68.10  ? 51  VAL A HG11 1 
ATOM 760  H HG12 . VAL A 1 51  ? 143.774 88.074  104.775 1.00 65.83  ? 51  VAL A HG12 1 
ATOM 761  H HG13 . VAL A 1 51  ? 142.842 88.221  103.499 1.00 65.52  ? 51  VAL A HG13 1 
ATOM 762  H HG21 . VAL A 1 51  ? 141.759 90.538  103.262 1.00 61.31  ? 51  VAL A HG21 1 
ATOM 763  H HG22 . VAL A 1 51  ? 140.723 89.458  103.792 1.00 60.44  ? 51  VAL A HG22 1 
ATOM 764  H HG23 . VAL A 1 51  ? 140.848 90.863  104.522 1.00 60.48  ? 51  VAL A HG23 1 
ATOM 765  N N    . PRO A 1 52  ? 143.304 87.508  107.551 1.00 69.72  ? 52  PRO A N    1 
ATOM 766  C CA   . PRO A 1 52  ? 144.255 87.404  108.672 1.00 78.28  ? 52  PRO A CA   1 
ATOM 767  C C    . PRO A 1 52  ? 145.512 88.240  108.498 1.00 84.01  ? 52  PRO A C    1 
ATOM 768  O O    . PRO A 1 52  ? 146.166 88.551  109.502 1.00 90.07  ? 52  PRO A O    1 
ATOM 769  C CB   . PRO A 1 52  ? 144.592 85.905  108.728 1.00 74.43  ? 52  PRO A CB   1 
ATOM 770  C CG   . PRO A 1 52  ? 143.672 85.228  107.775 1.00 71.39  ? 52  PRO A CG   1 
ATOM 771  C CD   . PRO A 1 52  ? 143.180 86.242  106.811 1.00 73.76  ? 52  PRO A CD   1 
ATOM 772  H HA   . PRO A 1 52  ? 143.821 87.657  109.502 1.00 72.77  ? 52  PRO A HA   1 
ATOM 773  H HB2  . PRO A 1 52  ? 145.514 85.773  108.458 1.00 74.37  ? 52  PRO A HB2  1 
ATOM 774  H HB3  . PRO A 1 52  ? 144.452 85.574  109.629 1.00 72.91  ? 52  PRO A HB3  1 
ATOM 775  H HG2  . PRO A 1 52  ? 144.158 84.531  107.306 1.00 72.15  ? 52  PRO A HG2  1 
ATOM 776  H HG3  . PRO A 1 52  ? 142.929 84.845  108.266 1.00 69.57  ? 52  PRO A HG3  1 
ATOM 777  H HD2  . PRO A 1 52  ? 143.734 86.252  106.016 1.00 71.38  ? 52  PRO A HD2  1 
ATOM 778  H HD3  . PRO A 1 52  ? 142.251 86.062  106.597 1.00 70.88  ? 52  PRO A HD3  1 
ATOM 779  N N    . LEU A 1 53  ? 145.877 88.612  107.270 1.00 79.34  ? 53  LEU A N    1 
ATOM 780  C CA   . LEU A 1 53  ? 147.125 89.341  107.067 1.00 84.37  ? 53  LEU A CA   1 
ATOM 781  C C    . LEU A 1 53  ? 147.083 90.714  107.728 1.00 87.25  ? 53  LEU A C    1 
ATOM 782  O O    . LEU A 1 53  ? 148.081 91.160  108.306 1.00 90.53  ? 53  LEU A O    1 
ATOM 783  C CB   . LEU A 1 53  ? 147.418 89.477  105.572 1.00 87.27  ? 53  LEU A CB   1 
ATOM 784  C CG   . LEU A 1 53  ? 148.682 90.261  105.200 1.00 88.13  ? 53  LEU A CG   1 
ATOM 785  C CD1  . LEU A 1 53  ? 149.893 89.776  105.987 1.00 88.22  ? 53  LEU A CD1  1 
ATOM 786  C CD2  . LEU A 1 53  ? 148.947 90.172  103.705 1.00 87.52  ? 53  LEU A CD2  1 
ATOM 787  H H    . LEU A 1 53  ? 145.429 88.457  106.552 1.00 77.43  ? 53  LEU A H    1 
ATOM 788  H HA   . LEU A 1 53  ? 147.848 88.838  107.471 1.00 84.01  ? 53  LEU A HA   1 
ATOM 789  H HB2  . LEU A 1 53  ? 147.512 88.587  105.199 1.00 86.47  ? 53  LEU A HB2  1 
ATOM 790  H HB3  . LEU A 1 53  ? 146.667 89.924  105.153 1.00 83.94  ? 53  LEU A HB3  1 
ATOM 791  H HG   . LEU A 1 53  ? 148.547 91.196  105.419 1.00 87.48  ? 53  LEU A HG   1 
ATOM 792  H HD11 . LEU A 1 53  ? 149.965 88.813  105.894 1.00 86.41  ? 53  LEU A HD11 1 
ATOM 793  H HD12 . LEU A 1 53  ? 150.689 90.203  105.633 1.00 86.17  ? 53  LEU A HD12 1 
ATOM 794  H HD13 . LEU A 1 53  ? 149.780 90.011  106.921 1.00 86.11  ? 53  LEU A HD13 1 
ATOM 795  H HD21 . LEU A 1 53  ? 149.032 89.239  103.454 1.00 86.76  ? 53  LEU A HD21 1 
ATOM 796  H HD22 . LEU A 1 53  ? 148.206 90.578  103.229 1.00 85.14  ? 53  LEU A HD22 1 
ATOM 797  H HD23 . LEU A 1 53  ? 149.769 90.645  103.503 1.00 87.41  ? 53  LEU A HD23 1 
ATOM 798  N N    . LEU A 1 54  ? 145.942 91.400  107.655 1.00 84.53  ? 54  LEU A N    1 
ATOM 799  C CA   . LEU A 1 54  ? 145.841 92.769  108.153 1.00 86.46  ? 54  LEU A CA   1 
ATOM 800  C C    . LEU A 1 54  ? 145.339 92.817  109.594 1.00 84.88  ? 54  LEU A C    1 
ATOM 801  O O    . LEU A 1 54  ? 146.006 93.372  110.473 1.00 88.45  ? 54  LEU A O    1 
ATOM 802  C CB   . LEU A 1 54  ? 144.919 93.588  107.243 1.00 77.81  ? 54  LEU A CB   1 
ATOM 803  C CG   . LEU A 1 54  ? 144.990 93.276  105.747 1.00 75.97  ? 54  LEU A CG   1 
ATOM 804  C CD1  . LEU A 1 54  ? 144.072 94.205  104.974 1.00 71.75  ? 54  LEU A CD1  1 
ATOM 805  C CD2  . LEU A 1 54  ? 146.418 93.387  105.236 1.00 82.98  ? 54  LEU A CD2  1 
ATOM 806  H H    . LEU A 1 54  ? 145.212 91.092  107.321 1.00 81.60  ? 54  LEU A H    1 
ATOM 807  H HA   . LEU A 1 54  ? 146.720 93.178  108.131 1.00 85.73  ? 54  LEU A HA   1 
ATOM 808  H HB2  . LEU A 1 54  ? 144.003 93.439  107.524 1.00 74.70  ? 54  LEU A HB2  1 
ATOM 809  H HB3  . LEU A 1 54  ? 145.139 94.526  107.352 1.00 79.39  ? 54  LEU A HB3  1 
ATOM 810  H HG   . LEU A 1 54  ? 144.688 92.366  105.599 1.00 74.96  ? 54  LEU A HG   1 
ATOM 811  H HD11 . LEU A 1 54  ? 144.559 95.012  104.744 1.00 73.95  ? 54  LEU A HD11 1 
ATOM 812  H HD12 . LEU A 1 54  ? 143.776 93.755  104.167 1.00 67.97  ? 54  LEU A HD12 1 
ATOM 813  H HD13 . LEU A 1 54  ? 143.308 94.425  105.528 1.00 67.80  ? 54  LEU A HD13 1 
ATOM 814  H HD21 . LEU A 1 54  ? 146.423 93.225  104.280 1.00 81.82  ? 54  LEU A HD21 1 
ATOM 815  H HD22 . LEU A 1 54  ? 146.750 94.279  105.422 1.00 83.53  ? 54  LEU A HD22 1 
ATOM 816  H HD23 . LEU A 1 54  ? 146.969 92.728  105.686 1.00 82.89  ? 54  LEU A HD23 1 
ATOM 817  N N    . ASP A 1 55  ? 144.162 92.239  109.849 1.00 78.77  ? 55  ASP A N    1 
ATOM 818  C CA   . ASP A 1 55  ? 143.545 92.375  111.164 1.00 81.04  ? 55  ASP A CA   1 
ATOM 819  C C    . ASP A 1 55  ? 144.402 91.739  112.252 1.00 86.16  ? 55  ASP A C    1 
ATOM 820  O O    . ASP A 1 55  ? 144.586 92.323  113.326 1.00 92.32  ? 55  ASP A O    1 
ATOM 821  C CB   . ASP A 1 55  ? 142.148 91.759  111.147 1.00 74.37  ? 55  ASP A CB   1 
ATOM 822  C CG   . ASP A 1 55  ? 141.237 92.419  110.132 1.00 70.71  ? 55  ASP A CG   1 
ATOM 823  O OD1  . ASP A 1 55  ? 141.748 92.896  109.097 1.00 64.82  ? 55  ASP A OD1  1 
ATOM 824  O OD2  . ASP A 1 55  ? 140.012 92.464  110.369 1.00 72.73  ? 55  ASP A OD2  1 
ATOM 825  H H    . ASP A 1 55  ? 143.710 91.772  109.286 1.00 77.16  ? 55  ASP A H    1 
ATOM 826  H HA   . ASP A 1 55  ? 143.453 93.318  111.372 1.00 80.46  ? 55  ASP A HA   1 
ATOM 827  H HB2  . ASP A 1 55  ? 142.221 90.819  110.921 1.00 71.74  ? 55  ASP A HB2  1 
ATOM 828  H HB3  . ASP A 1 55  ? 141.746 91.861  112.024 1.00 71.74  ? 55  ASP A HB3  1 
ATOM 829  N N    . ASN A 1 56  ? 144.938 90.548  111.997 1.00 80.34  ? 56  ASN A N    1 
ATOM 830  C CA   . ASN A 1 56  ? 145.809 89.886  112.963 1.00 88.70  ? 56  ASN A CA   1 
ATOM 831  C C    . ASN A 1 56  ? 147.178 90.552  112.908 1.00 92.85  ? 56  ASN A C    1 
ATOM 832  O O    . ASN A 1 56  ? 147.938 90.353  111.954 1.00 90.09  ? 56  ASN A O    1 
ATOM 833  C CB   . ASN A 1 56  ? 145.901 88.391  112.673 1.00 92.52  ? 56  ASN A CB   1 
ATOM 834  C CG   . ASN A 1 56  ? 146.350 87.591  113.881 1.00 86.69  ? 56  ASN A CG   1 
ATOM 835  O OD1  . ASN A 1 56  ? 147.507 87.669  114.297 1.00 84.21  ? 56  ASN A OD1  1 
ATOM 836  N ND2  . ASN A 1 56  ? 145.433 86.822  114.457 1.00 73.42  ? 56  ASN A ND2  1 
ATOM 837  H H    . ASN A 1 56  ? 144.813 90.103  111.272 1.00 80.30  ? 56  ASN A H    1 
ATOM 838  H HA   . ASN A 1 56  ? 145.447 90.003  113.856 1.00 88.19  ? 56  ASN A HA   1 
ATOM 839  H HB2  . ASN A 1 56  ? 145.026 88.067  112.407 1.00 84.39  ? 56  ASN A HB2  1 
ATOM 840  H HB3  . ASN A 1 56  ? 146.541 88.245  111.960 1.00 89.59  ? 56  ASN A HB3  1 
ATOM 841  H HD21 . ASN A 1 56  ? 144.634 86.794  114.140 1.00 75.20  ? 56  ASN A HD21 1 
ATOM 842  H HD22 . ASN A 1 56  ? 145.639 86.350  115.146 1.00 78.32  ? 56  ASN A HD22 1 
ATOM 843  N N    . SER A 1 57  ? 147.493 91.346  113.934 1.00 98.43  ? 57  SER A N    1 
ATOM 844  C CA   . SER A 1 57  ? 148.703 92.161  113.899 1.00 103.82 ? 57  SER A CA   1 
ATOM 845  C C    . SER A 1 57  ? 149.964 91.309  113.840 1.00 113.76 ? 57  SER A C    1 
ATOM 846  O O    . SER A 1 57  ? 150.993 91.763  113.327 1.00 115.39 ? 57  SER A O    1 
ATOM 847  C CB   . SER A 1 57  ? 148.746 93.080  115.120 1.00 92.12  ? 57  SER A CB   1 
ATOM 848  H H    . SER A 1 57  ? 147.028 91.428  114.652 1.00 94.90  ? 57  SER A H    1 
ATOM 849  H HA   . SER A 1 57  ? 148.683 92.719  113.106 1.00 99.29  ? 57  SER A HA   1 
ATOM 850  N N    . THR A 1 58  ? 149.912 90.082  114.362 1.00 112.27 ? 58  THR A N    1 
ATOM 851  C CA   . THR A 1 58  ? 151.106 89.243  114.391 1.00 110.82 ? 58  THR A CA   1 
ATOM 852  C C    . THR A 1 58  ? 151.615 88.963  112.982 1.00 112.44 ? 58  THR A C    1 
ATOM 853  O O    . THR A 1 58  ? 152.808 89.123  112.696 1.00 113.44 ? 58  THR A O    1 
ATOM 854  C CB   . THR A 1 58  ? 150.808 87.935  115.124 1.00 112.01 ? 58  THR A CB   1 
ATOM 855  H H    . THR A 1 58  ? 149.209 89.719  114.700 1.00 106.38 ? 58  THR A H    1 
ATOM 856  H HA   . THR A 1 58  ? 151.807 89.707  114.877 1.00 109.51 ? 58  THR A HA   1 
ATOM 857  N N    . ALA A 1 59  ? 150.721 88.545  112.083 1.00 111.48 ? 59  ALA A N    1 
ATOM 858  C CA   . ALA A 1 59  ? 151.140 88.225  110.722 1.00 115.46 ? 59  ALA A CA   1 
ATOM 859  C C    . ALA A 1 59  ? 151.689 89.454  110.009 1.00 121.32 ? 59  ALA A C    1 
ATOM 860  O O    . ALA A 1 59  ? 152.716 89.377  109.324 1.00 119.94 ? 59  ALA A O    1 
ATOM 861  C CB   . ALA A 1 59  ? 149.970 87.629  109.940 1.00 105.34 ? 59  ALA A CB   1 
ATOM 862  H H    . ALA A 1 59  ? 149.881 88.441  112.235 1.00 106.92 ? 59  ALA A H    1 
ATOM 863  H HA   . ALA A 1 59  ? 151.845 87.560  110.758 1.00 114.06 ? 59  ALA A HA   1 
ATOM 864  H HB1  . ALA A 1 59  ? 149.249 88.277  109.908 1.00 101.66 ? 59  ALA A HB1  1 
ATOM 865  H HB2  . ALA A 1 59  ? 150.267 87.419  109.041 1.00 103.87 ? 59  ALA A HB2  1 
ATOM 866  H HB3  . ALA A 1 59  ? 149.671 86.822  110.387 1.00 104.84 ? 59  ALA A HB3  1 
ATOM 867  N N    . GLN A 1 60  ? 151.016 90.598  110.154 1.00 121.41 ? 60  GLN A N    1 
ATOM 868  C CA   . GLN A 1 60  ? 151.483 91.813  109.496 1.00 116.93 ? 60  GLN A CA   1 
ATOM 869  C C    . GLN A 1 60  ? 152.853 92.230  110.015 1.00 120.56 ? 60  GLN A C    1 
ATOM 870  O O    . GLN A 1 60  ? 153.735 92.603  109.233 1.00 122.64 ? 60  GLN A O    1 
ATOM 871  C CB   . GLN A 1 60  ? 150.469 92.939  109.698 1.00 108.01 ? 60  GLN A CB   1 
ATOM 872  H H    . GLN A 1 60  ? 150.300 90.693  110.620 1.00 112.93 ? 60  GLN A H    1 
ATOM 873  H HA   . GLN A 1 60  ? 151.561 91.646  108.544 1.00 113.61 ? 60  GLN A HA   1 
ATOM 874  N N    . ALA A 1 61  ? 153.053 92.171  111.334 1.00 119.72 ? 61  ALA A N    1 
ATOM 875  C CA   . ALA A 1 61  ? 154.337 92.548  111.911 1.00 118.08 ? 61  ALA A CA   1 
ATOM 876  C C    . ALA A 1 61  ? 155.426 91.527  111.616 1.00 125.47 ? 61  ALA A C    1 
ATOM 877  O O    . ALA A 1 61  ? 156.612 91.864  111.702 1.00 129.00 ? 61  ALA A O    1 
ATOM 878  C CB   . ALA A 1 61  ? 154.198 92.734  113.423 1.00 110.18 ? 61  ALA A CB   1 
ATOM 879  H H    . ALA A 1 61  ? 152.465 91.917  111.908 1.00 117.33 ? 61  ALA A H    1 
ATOM 880  H HA   . ALA A 1 61  ? 154.614 93.397  111.531 1.00 119.31 ? 61  ALA A HA   1 
ATOM 881  H HB1  . ALA A 1 61  ? 153.546 93.431  113.596 1.00 112.85 ? 61  ALA A HB1  1 
ATOM 882  H HB2  . ALA A 1 61  ? 153.901 91.898  113.817 1.00 113.58 ? 61  ALA A HB2  1 
ATOM 883  H HB3  . ALA A 1 61  ? 155.059 92.987  113.790 1.00 114.14 ? 61  ALA A HB3  1 
ATOM 884  N N    . SER A 1 62  ? 155.054 90.292  111.274 1.00 128.16 ? 62  SER A N    1 
ATOM 885  C CA   . SER A 1 62  ? 156.058 89.277  110.972 1.00 131.39 ? 62  SER A CA   1 
ATOM 886  C C    . SER A 1 62  ? 156.908 89.681  109.773 1.00 141.85 ? 62  SER A C    1 
ATOM 887  O O    . SER A 1 62  ? 158.133 89.512  109.786 1.00 147.22 ? 62  SER A O    1 
ATOM 888  C CB   . SER A 1 62  ? 155.380 87.931  110.717 1.00 121.74 ? 62  SER A CB   1 
ATOM 889  H H    . SER A 1 62  ? 154.240 90.021  111.210 1.00 123.81 ? 62  SER A H    1 
ATOM 890  H HA   . SER A 1 62  ? 156.647 89.177  111.736 1.00 130.38 ? 62  SER A HA   1 
ATOM 891  N N    . VAL A 1 63  ? 156.279 90.215  108.731 1.00 144.68 ? 63  VAL A N    1 
ATOM 892  C CA   . VAL A 1 63  ? 157.035 90.611  107.538 1.00 147.75 ? 63  VAL A CA   1 
ATOM 893  C C    . VAL A 1 63  ? 157.993 91.739  107.902 1.00 149.94 ? 63  VAL A C    1 
ATOM 894  O O    . VAL A 1 63  ? 157.584 92.708  108.571 1.00 145.54 ? 63  VAL A O    1 
ATOM 895  C CB   . VAL A 1 63  ? 156.079 91.045  106.414 1.00 141.18 ? 63  VAL A CB   1 
ATOM 896  H H    . VAL A 1 63  ? 155.432 90.358  108.685 1.00 136.33 ? 63  VAL A H    1 
ATOM 897  H HA   . VAL A 1 63  ? 157.556 89.856  107.222 1.00 144.72 ? 63  VAL A HA   1 
ATOM 898  N N    . PRO A 1 64  ? 159.261 91.672  107.501 1.00 154.42 ? 64  PRO A N    1 
ATOM 899  C CA   . PRO A 1 64  ? 160.189 92.759  107.830 1.00 154.19 ? 64  PRO A CA   1 
ATOM 900  C C    . PRO A 1 64  ? 159.749 94.076  107.210 1.00 153.37 ? 64  PRO A C    1 
ATOM 901  O O    . PRO A 1 64  ? 159.170 94.116  106.122 1.00 148.78 ? 64  PRO A O    1 
ATOM 902  C CB   . PRO A 1 64  ? 161.522 92.279  107.244 1.00 149.86 ? 64  PRO A CB   1 
ATOM 903  H HA   . PRO A 1 64  ? 160.272 92.860  108.791 1.00 151.61 ? 64  PRO A HA   1 
ATOM 904  N N    . GLY A 1 65  ? 160.030 95.164  107.922 1.00 150.20 ? 65  GLY A N    1 
ATOM 905  C CA   . GLY A 1 65  ? 159.657 96.473  107.431 1.00 144.96 ? 65  GLY A CA   1 
ATOM 906  C C    . GLY A 1 65  ? 158.156 96.703  107.520 1.00 141.53 ? 65  GLY A C    1 
ATOM 907  O O    . GLY A 1 65  ? 157.433 96.050  108.278 1.00 137.96 ? 65  GLY A O    1 
ATOM 908  H H    . GLY A 1 65  ? 160.431 95.166  108.683 1.00 149.02 ? 65  GLY A H    1 
ATOM 909  H HA2  . GLY A 1 65  ? 160.105 97.156  107.954 1.00 146.07 ? 65  GLY A HA2  1 
ATOM 910  H HA3  . GLY A 1 65  ? 159.930 96.564  106.504 1.00 146.17 ? 65  GLY A HA3  1 
ATOM 911  N N    . ALA A 1 66  ? 157.690 97.658  106.718 1.00 135.35 ? 66  ALA A N    1 
ATOM 912  C CA   . ALA A 1 66  ? 156.286 98.036  106.679 1.00 124.51 ? 66  ALA A CA   1 
ATOM 913  C C    . ALA A 1 66  ? 155.782 98.001  105.245 1.00 118.22 ? 66  ALA A C    1 
ATOM 914  O O    . ALA A 1 66  ? 156.487 98.413  104.319 1.00 113.99 ? 66  ALA A O    1 
ATOM 915  C CB   . ALA A 1 66  ? 156.069 99.433  107.271 1.00 115.16 ? 66  ALA A CB   1 
ATOM 916  H H    . ALA A 1 66  ? 158.182 98.109  106.175 1.00 134.20 ? 66  ALA A H    1 
ATOM 917  H HA   . ALA A 1 66  ? 155.766 97.403  107.198 1.00 127.74 ? 66  ALA A HA   1 
ATOM 918  H HB1  . ALA A 1 66  ? 155.125 99.651  107.227 1.00 118.37 ? 66  ALA A HB1  1 
ATOM 919  H HB2  . ALA A 1 66  ? 156.367 99.435  108.194 1.00 120.34 ? 66  ALA A HB2  1 
ATOM 920  H HB3  . ALA A 1 66  ? 156.581 100.076 106.756 1.00 118.60 ? 66  ALA A HB3  1 
ATOM 921  N N    . LEU A 1 67  ? 154.560 97.504  105.071 1.00 112.75 ? 67  LEU A N    1 
ATOM 922  C CA   . LEU A 1 67  ? 153.883 97.487  103.782 1.00 105.51 ? 67  LEU A CA   1 
ATOM 923  C C    . LEU A 1 67  ? 152.587 98.274  103.905 1.00 104.10 ? 67  LEU A C    1 
ATOM 924  O O    . LEU A 1 67  ? 151.771 97.997  104.791 1.00 100.16 ? 67  LEU A O    1 
ATOM 925  C CB   . LEU A 1 67  ? 153.596 96.054  103.326 1.00 99.73  ? 67  LEU A CB   1 
ATOM 926  H H    . LEU A 1 67  ? 154.092 97.160  105.705 1.00 113.20 ? 67  LEU A H    1 
ATOM 927  H HA   . LEU A 1 67  ? 154.440 97.916  103.114 1.00 107.22 ? 67  LEU A HA   1 
ATOM 928  N N    . GLY A 1 68  ? 152.399 99.247  103.018 1.00 100.43 ? 68  GLY A N    1 
ATOM 929  C CA   . GLY A 1 68  ? 151.239 100.104 103.067 1.00 95.36  ? 68  GLY A CA   1 
ATOM 930  C C    . GLY A 1 68  ? 149.949 99.317  102.954 1.00 92.93  ? 68  GLY A C    1 
ATOM 931  O O    . GLY A 1 68  ? 149.864 98.332  102.214 1.00 95.13  ? 68  GLY A O    1 
ATOM 932  H H    . GLY A 1 68  ? 152.939 99.426  102.373 1.00 101.01 ? 68  GLY A H    1 
ATOM 933  H HA2  . GLY A 1 68  ? 151.247 100.591 103.905 1.00 96.53  ? 68  GLY A HA2  1 
ATOM 934  H HA3  . GLY A 1 68  ? 151.277 100.743 102.338 1.00 96.90  ? 68  GLY A HA3  1 
ATOM 935  N N    . PRO A 1 69  ? 148.913 99.734  103.690 1.00 93.27  ? 69  PRO A N    1 
ATOM 936  C CA   . PRO A 1 69  ? 147.647 98.982  103.633 1.00 95.87  ? 69  PRO A CA   1 
ATOM 937  C C    . PRO A 1 69  ? 147.060 98.904  102.235 1.00 92.97  ? 69  PRO A C    1 
ATOM 938  O O    . PRO A 1 69  ? 146.522 97.858  101.851 1.00 89.63  ? 69  PRO A O    1 
ATOM 939  C CB   . PRO A 1 69  ? 146.738 99.757  104.596 1.00 98.45  ? 69  PRO A CB   1 
ATOM 940  C CG   . PRO A 1 69  ? 147.310 101.130 104.643 1.00 97.61  ? 69  PRO A CG   1 
ATOM 941  C CD   . PRO A 1 69  ? 148.790 100.962 104.494 1.00 94.03  ? 69  PRO A CD   1 
ATOM 942  H HA   . PRO A 1 69  ? 147.777 98.084  103.975 1.00 95.53  ? 69  PRO A HA   1 
ATOM 943  H HB2  . PRO A 1 69  ? 145.832 99.774  104.251 1.00 96.34  ? 69  PRO A HB2  1 
ATOM 944  H HB3  . PRO A 1 69  ? 146.764 99.344  105.474 1.00 97.27  ? 69  PRO A HB3  1 
ATOM 945  H HG2  . PRO A 1 69  ? 146.950 101.656 103.912 1.00 96.42  ? 69  PRO A HG2  1 
ATOM 946  H HG3  . PRO A 1 69  ? 147.098 101.541 105.496 1.00 96.54  ? 69  PRO A HG3  1 
ATOM 947  H HD2  . PRO A 1 69  ? 149.166 101.719 104.017 1.00 93.75  ? 69  PRO A HD2  1 
ATOM 948  H HD3  . PRO A 1 69  ? 149.206 100.843 105.362 1.00 95.60  ? 69  PRO A HD3  1 
ATOM 949  N N    . GLU A 1 70  ? 147.155 99.984  101.455 1.00 92.82  ? 70  GLU A N    1 
ATOM 950  C CA   . GLU A 1 70  ? 146.616 99.958  100.099 1.00 88.60  ? 70  GLU A CA   1 
ATOM 951  C C    . GLU A 1 70  ? 147.328 98.917  99.241  1.00 88.71  ? 70  GLU A C    1 
ATOM 952  O O    . GLU A 1 70  ? 146.687 98.205  98.459  1.00 84.70  ? 70  GLU A O    1 
ATOM 953  C CB   . GLU A 1 70  ? 146.707 101.345 99.450  1.00 94.16  ? 70  GLU A CB   1 
ATOM 954  C CG   . GLU A 1 70  ? 148.109 101.859 99.066  1.00 96.45  ? 70  GLU A CG   1 
ATOM 955  C CD   . GLU A 1 70  ? 149.169 101.676 100.139 1.00 95.11  ? 70  GLU A CD   1 
ATOM 956  O OE1  . GLU A 1 70  ? 148.817 101.363 101.293 1.00 98.52  ? 70  GLU A OE1  1 
ATOM 957  O OE2  . GLU A 1 70  ? 150.365 101.848 99.822  1.00 94.55  ? 70  GLU A OE2  1 
ATOM 958  H H    . GLU A 1 70  ? 147.498 100.732 101.694 1.00 94.21  ? 70  GLU A H    1 
ATOM 959  H HA   . GLU A 1 70  ? 145.678 99.712  100.142 1.00 89.79  ? 70  GLU A HA   1 
ATOM 960  H HB2  . GLU A 1 70  ? 146.178 101.330 98.637  1.00 93.22  ? 70  GLU A HB2  1 
ATOM 961  H HB3  . GLU A 1 70  ? 146.325 101.990 100.066 1.00 94.06  ? 70  GLU A HB3  1 
ATOM 962  H HG2  . GLU A 1 70  ? 148.407 101.384 98.275  1.00 94.81  ? 70  GLU A HG2  1 
ATOM 963  H HG3  . GLU A 1 70  ? 148.048 102.808 98.874  1.00 95.34  ? 70  GLU A HG3  1 
ATOM 964  N N    . ALA A 1 71  ? 148.651 98.810  99.374  1.00 87.91  ? 71  ALA A N    1 
ATOM 965  C CA   . ALA A 1 71  ? 149.401 97.849  98.575  1.00 88.60  ? 71  ALA A CA   1 
ATOM 966  C C    . ALA A 1 71  ? 149.230 96.426  99.090  1.00 87.28  ? 71  ALA A C    1 
ATOM 967  O O    . ALA A 1 71  ? 149.251 95.479  98.297  1.00 87.26  ? 71  ALA A O    1 
ATOM 968  C CB   . ALA A 1 71  ? 150.883 98.224  98.555  1.00 90.26  ? 71  ALA A CB   1 
ATOM 969  H H    . ALA A 1 71  ? 149.131 99.266  99.921  1.00 90.38  ? 71  ALA A H    1 
ATOM 970  H HA   . ALA A 1 71  ? 149.074 97.877  97.663  1.00 89.42  ? 71  ALA A HA   1 
ATOM 971  H HB1  . ALA A 1 71  ? 151.364 97.580  98.012  1.00 90.35  ? 71  ALA A HB1  1 
ATOM 972  H HB2  . ALA A 1 71  ? 150.978 99.112  98.176  1.00 89.38  ? 71  ALA A HB2  1 
ATOM 973  H HB3  . ALA A 1 71  ? 151.224 98.214  99.463  1.00 91.55  ? 71  ALA A HB3  1 
ATOM 974  N N    . LEU A 1 72  ? 149.064 96.256  100.401 1.00 88.60  ? 72  LEU A N    1 
ATOM 975  C CA   . LEU A 1 72  ? 148.900 94.931  100.982 1.00 84.40  ? 72  LEU A CA   1 
ATOM 976  C C    . LEU A 1 72  ? 147.465 94.424  100.900 1.00 82.57  ? 72  LEU A C    1 
ATOM 977  O O    . LEU A 1 72  ? 147.223 93.249  101.195 1.00 85.42  ? 72  LEU A O    1 
ATOM 978  C CB   . LEU A 1 72  ? 149.358 94.947  102.444 1.00 87.76  ? 72  LEU A CB   1 
ATOM 979  C CG   . LEU A 1 72  ? 149.748 93.604  103.066 1.00 90.41  ? 72  LEU A CG   1 
ATOM 980  C CD1  . LEU A 1 72  ? 150.874 92.944  102.282 1.00 92.62  ? 72  LEU A CD1  1 
ATOM 981  C CD2  . LEU A 1 72  ? 150.146 93.787  104.522 1.00 90.74  ? 72  LEU A CD2  1 
ATOM 982  H H    . LEU A 1 72  ? 149.043 96.896  100.975 1.00 90.92  ? 72  LEU A H    1 
ATOM 983  H HA   . LEU A 1 72  ? 149.461 94.309  100.495 1.00 85.49  ? 72  LEU A HA   1 
ATOM 984  H HB2  . LEU A 1 72  ? 150.131 95.529  102.511 1.00 90.48  ? 72  LEU A HB2  1 
ATOM 985  H HB3  . LEU A 1 72  ? 148.637 95.312  102.981 1.00 88.78  ? 72  LEU A HB3  1 
ATOM 986  H HG   . LEU A 1 72  ? 148.981 93.011  103.040 1.00 88.83  ? 72  LEU A HG   1 
ATOM 987  H HD11 . LEU A 1 72  ? 151.281 92.257  102.832 1.00 92.46  ? 72  LEU A HD11 1 
ATOM 988  H HD12 . LEU A 1 72  ? 150.510 92.549  101.475 1.00 88.89  ? 72  LEU A HD12 1 
ATOM 989  H HD13 . LEU A 1 72  ? 151.536 93.616  102.054 1.00 90.22  ? 72  LEU A HD13 1 
ATOM 990  H HD21 . LEU A 1 72  ? 150.359 92.920  104.902 1.00 90.36  ? 72  LEU A HD21 1 
ATOM 991  H HD22 . LEU A 1 72  ? 150.922 94.367  104.566 1.00 91.61  ? 72  LEU A HD22 1 
ATOM 992  H HD23 . LEU A 1 72  ? 149.406 94.187  105.004 1.00 89.97  ? 72  LEU A HD23 1 
ATOM 993  N N    . LEU A 1 73  ? 146.511 95.278  100.525 1.00 79.98  ? 73  LEU A N    1 
ATOM 994  C CA   . LEU A 1 73  ? 145.133 94.830  100.359 1.00 73.36  ? 73  LEU A CA   1 
ATOM 995  C C    . LEU A 1 73  ? 144.933 94.070  99.054  1.00 79.54  ? 73  LEU A C    1 
ATOM 996  O O    . LEU A 1 73  ? 144.125 93.136  99.005  1.00 83.45  ? 73  LEU A O    1 
ATOM 997  C CB   . LEU A 1 73  ? 144.184 96.028  100.417 1.00 71.41  ? 73  LEU A CB   1 
ATOM 998  C CG   . LEU A 1 73  ? 142.722 95.743  100.065 1.00 69.43  ? 73  LEU A CG   1 
ATOM 999  C CD1  . LEU A 1 73  ? 141.792 96.434  101.047 1.00 68.66  ? 73  LEU A CD1  1 
ATOM 1000 C CD2  . LEU A 1 73  ? 142.415 96.174  98.639  1.00 73.37  ? 73  LEU A CD2  1 
ATOM 1001 H H    . LEU A 1 73  ? 146.635 96.114  100.363 1.00 83.23  ? 73  LEU A H    1 
ATOM 1002 H HA   . LEU A 1 73  ? 144.906 94.234  101.090 1.00 75.53  ? 73  LEU A HA   1 
ATOM 1003 H HB2  . LEU A 1 73  ? 144.200 96.387  101.318 1.00 75.41  ? 73  LEU A HB2  1 
ATOM 1004 H HB3  . LEU A 1 73  ? 144.505 96.701  99.796  1.00 78.35  ? 73  LEU A HB3  1 
ATOM 1005 H HG   . LEU A 1 73  ? 142.562 94.788  100.129 1.00 71.26  ? 73  LEU A HG   1 
ATOM 1006 H HD11 . LEU A 1 73  ? 140.874 96.254  100.791 1.00 66.23  ? 73  LEU A HD11 1 
ATOM 1007 H HD12 . LEU A 1 73  ? 141.962 96.089  101.938 1.00 67.73  ? 73  LEU A HD12 1 
ATOM 1008 H HD13 . LEU A 1 73  ? 141.962 97.388  101.023 1.00 69.90  ? 73  LEU A HD13 1 
ATOM 1009 H HD21 . LEU A 1 73  ? 141.490 95.963  98.439  1.00 71.25  ? 73  LEU A HD21 1 
ATOM 1010 H HD22 . LEU A 1 73  ? 142.562 97.129  98.559  1.00 74.30  ? 73  LEU A HD22 1 
ATOM 1011 H HD23 . LEU A 1 73  ? 143.001 95.697  98.030  1.00 73.64  ? 73  LEU A HD23 1 
ATOM 1012 N N    . ALA A 1 74  ? 145.649 94.453  97.995  1.00 79.77  ? 74  ALA A N    1 
ATOM 1013 C CA   . ALA A 1 74  ? 145.456 93.812  96.698  1.00 77.54  ? 74  ALA A CA   1 
ATOM 1014 C C    . ALA A 1 74  ? 145.832 92.336  96.745  1.00 83.76  ? 74  ALA A C    1 
ATOM 1015 O O    . ALA A 1 74  ? 145.190 91.503  96.095  1.00 83.87  ? 74  ALA A O    1 
ATOM 1016 C CB   . ALA A 1 74  ? 146.274 94.536  95.630  1.00 77.51  ? 74  ALA A CB   1 
ATOM 1017 H H    . ALA A 1 74  ? 146.246 95.073  98.002  1.00 80.13  ? 74  ALA A H    1 
ATOM 1018 H HA   . ALA A 1 74  ? 144.520 93.875  96.452  1.00 76.93  ? 74  ALA A HA   1 
ATOM 1019 H HB1  . ALA A 1 74  ? 146.139 94.094  94.776  1.00 79.46  ? 74  ALA A HB1  1 
ATOM 1020 H HB2  . ALA A 1 74  ? 145.979 95.459  95.576  1.00 79.18  ? 74  ALA A HB2  1 
ATOM 1021 H HB3  . ALA A 1 74  ? 147.212 94.502  95.874  1.00 78.65  ? 74  ALA A HB3  1 
ATOM 1022 N N    . VAL A 1 75  ? 146.874 91.993  97.507  1.00 85.22  ? 75  VAL A N    1 
ATOM 1023 C CA   . VAL A 1 75  ? 147.372 90.623  97.526  1.00 83.24  ? 75  VAL A CA   1 
ATOM 1024 C C    . VAL A 1 75  ? 146.345 89.648  98.082  1.00 79.95  ? 75  VAL A C    1 
ATOM 1025 O O    . VAL A 1 75  ? 146.500 88.433  97.917  1.00 86.64  ? 75  VAL A O    1 
ATOM 1026 C CB   . VAL A 1 75  ? 148.683 90.531  98.336  1.00 85.66  ? 75  VAL A CB   1 
ATOM 1027 C CG1  . VAL A 1 75  ? 149.833 91.144  97.557  1.00 90.51  ? 75  VAL A CG1  1 
ATOM 1028 C CG2  . VAL A 1 75  ? 148.530 91.200  99.695  1.00 89.63  ? 75  VAL A CG2  1 
ATOM 1029 H H    . VAL A 1 75  ? 147.302 92.537  98.015  1.00 84.21  ? 75  VAL A H    1 
ATOM 1030 H HA   . VAL A 1 75  ? 147.573 90.355  96.616  1.00 84.60  ? 75  VAL A HA   1 
ATOM 1031 H HB   . VAL A 1 75  ? 148.893 89.595  98.486  1.00 84.23  ? 75  VAL A HB   1 
ATOM 1032 H HG11 . VAL A 1 75  ? 150.658 90.993  98.043  1.00 85.82  ? 75  VAL A HG11 1 
ATOM 1033 H HG12 . VAL A 1 75  ? 149.880 90.725  96.684  1.00 86.42  ? 75  VAL A HG12 1 
ATOM 1034 H HG13 . VAL A 1 75  ? 149.674 92.096  97.459  1.00 87.23  ? 75  VAL A HG13 1 
ATOM 1035 H HG21 . VAL A 1 75  ? 149.210 90.855  100.295 1.00 88.77  ? 75  VAL A HG21 1 
ATOM 1036 H HG22 . VAL A 1 75  ? 148.642 92.157  99.588  1.00 86.88  ? 75  VAL A HG22 1 
ATOM 1037 H HG23 . VAL A 1 75  ? 147.649 91.005  100.050 1.00 86.55  ? 75  VAL A HG23 1 
ATOM 1038 N N    . SER A 1 76  ? 145.297 90.144  98.749  1.00 69.61  ? 76  SER A N    1 
ATOM 1039 C CA   . SER A 1 76  ? 144.328 89.273  99.405  1.00 75.09  ? 76  SER A CA   1 
ATOM 1040 C C    . SER A 1 76  ? 142.885 89.639  99.069  1.00 70.01  ? 76  SER A C    1 
ATOM 1041 O O    . SER A 1 76  ? 141.965 89.150  99.731  1.00 71.81  ? 76  SER A O    1 
ATOM 1042 C CB   . SER A 1 76  ? 144.527 89.306  100.921 1.00 80.43  ? 76  SER A CB   1 
ATOM 1043 O OG   . SER A 1 76  ? 143.584 90.167  101.531 1.00 82.66  ? 76  SER A OG   1 
ATOM 1044 H H    . SER A 1 76  ? 145.128 90.983  98.837  1.00 75.69  ? 76  SER A H    1 
ATOM 1045 H HA   . SER A 1 76  ? 144.470 88.360  99.112  1.00 77.64  ? 76  SER A HA   1 
ATOM 1046 H HB2  . SER A 1 76  ? 144.417 88.410  101.277 1.00 80.25  ? 76  SER A HB2  1 
ATOM 1047 H HB3  . SER A 1 76  ? 145.419 89.633  101.117 1.00 77.24  ? 76  SER A HB3  1 
ATOM 1048 H HG   . SER A 1 76  ? 143.964 90.634  102.115 1.00 79.60  ? 76  SER A HG   1 
ATOM 1049 N N    . ILE A 1 77  ? 142.657 90.477  98.062  1.00 72.46  ? 77  ILE A N    1 
ATOM 1050 C CA   . ILE A 1 77  ? 141.296 90.822  97.655  1.00 76.48  ? 77  ILE A CA   1 
ATOM 1051 C C    . ILE A 1 77  ? 141.235 90.925  96.135  1.00 83.16  ? 77  ILE A C    1 
ATOM 1052 O O    . ILE A 1 77  ? 141.886 91.805  95.552  1.00 83.50  ? 77  ILE A O    1 
ATOM 1053 C CB   . ILE A 1 77  ? 140.829 92.131  98.312  1.00 77.91  ? 77  ILE A CB   1 
ATOM 1054 C CG1  . ILE A 1 77  ? 140.649 91.946  99.822  1.00 66.25  ? 77  ILE A CG1  1 
ATOM 1055 C CG2  . ILE A 1 77  ? 139.526 92.609  97.682  1.00 79.95  ? 77  ILE A CG2  1 
ATOM 1056 C CD1  . ILE A 1 77  ? 139.457 91.087  100.210 1.00 59.94  ? 77  ILE A CD1  1 
ATOM 1057 H H    . ILE A 1 77  ? 143.270 90.865  97.599  1.00 76.12  ? 77  ILE A H    1 
ATOM 1058 H HA   . ILE A 1 77  ? 140.697 90.120  97.946  1.00 74.64  ? 77  ILE A HA   1 
ATOM 1059 H HB   . ILE A 1 77  ? 141.508 92.808  98.164  1.00 78.31  ? 77  ILE A HB   1 
ATOM 1060 H HG12 . ILE A 1 77  ? 141.445 91.532  100.188 1.00 68.93  ? 77  ILE A HG12 1 
ATOM 1061 H HG13 . ILE A 1 77  ? 140.524 92.819  100.227 1.00 68.80  ? 77  ILE A HG13 1 
ATOM 1062 H HG21 . ILE A 1 77  ? 139.093 93.228  98.290  1.00 76.47  ? 77  ILE A HG21 1 
ATOM 1063 H HG22 . ILE A 1 77  ? 139.721 93.055  96.843  1.00 81.68  ? 77  ILE A HG22 1 
ATOM 1064 H HG23 . ILE A 1 77  ? 138.949 91.844  97.527  1.00 75.45  ? 77  ILE A HG23 1 
ATOM 1065 H HD11 . ILE A 1 77  ? 139.462 90.961  101.172 1.00 61.86  ? 77  ILE A HD11 1 
ATOM 1066 H HD12 . ILE A 1 77  ? 138.639 91.535  99.943  1.00 60.91  ? 77  ILE A HD12 1 
ATOM 1067 H HD13 . ILE A 1 77  ? 139.524 90.228  99.767  1.00 65.21  ? 77  ILE A HD13 1 
ATOM 1068 N N    . PRO A 1 78  ? 140.478 90.068  95.451  1.00 79.30  ? 78  PRO A N    1 
ATOM 1069 C CA   . PRO A 1 78  ? 140.392 90.179  93.999  1.00 85.84  ? 78  PRO A CA   1 
ATOM 1070 C C    . PRO A 1 78  ? 139.794 91.511  93.598  1.00 89.65  ? 78  PRO A C    1 
ATOM 1071 O O    . PRO A 1 78  ? 138.952 92.077  94.321  1.00 82.31  ? 78  PRO A O    1 
ATOM 1072 C CB   . PRO A 1 78  ? 139.478 89.009  93.607  1.00 84.06  ? 78  PRO A CB   1 
ATOM 1073 C CG   . PRO A 1 78  ? 139.565 88.055  94.732  1.00 78.39  ? 78  PRO A CG   1 
ATOM 1074 C CD   . PRO A 1 78  ? 139.753 88.888  95.955  1.00 75.07  ? 78  PRO A CD   1 
ATOM 1075 H HA   . PRO A 1 78  ? 141.267 90.061  93.599  1.00 83.80  ? 78  PRO A HA   1 
ATOM 1076 H HB2  . PRO A 1 78  ? 138.569 89.328  93.499  1.00 82.51  ? 78  PRO A HB2  1 
ATOM 1077 H HB3  . PRO A 1 78  ? 139.800 88.604  92.787  1.00 82.72  ? 78  PRO A HB3  1 
ATOM 1078 H HG2  . PRO A 1 78  ? 138.742 87.545  94.789  1.00 80.10  ? 78  PRO A HG2  1 
ATOM 1079 H HG3  . PRO A 1 78  ? 140.323 87.464  94.600  1.00 77.83  ? 78  PRO A HG3  1 
ATOM 1080 H HD2  . PRO A 1 78  ? 138.895 89.147  96.327  1.00 76.98  ? 78  PRO A HD2  1 
ATOM 1081 H HD3  . PRO A 1 78  ? 140.292 88.408  96.602  1.00 76.96  ? 78  PRO A HD3  1 
ATOM 1082 N N    . PRO A 1 79  ? 140.202 92.059  92.446  1.00 100.11 ? 79  PRO A N    1 
ATOM 1083 C CA   . PRO A 1 79  ? 139.602 93.320  91.988  1.00 95.21  ? 79  PRO A CA   1 
ATOM 1084 C C    . PRO A 1 79  ? 138.147 93.142  91.587  1.00 87.95  ? 79  PRO A C    1 
ATOM 1085 O O    . PRO A 1 79  ? 137.847 92.481  90.588  1.00 81.66  ? 79  PRO A O    1 
ATOM 1086 C CB   . PRO A 1 79  ? 140.476 93.713  90.790  1.00 96.63  ? 79  PRO A CB   1 
ATOM 1087 C CG   . PRO A 1 79  ? 141.053 92.433  90.304  1.00 100.03 ? 79  PRO A CG   1 
ATOM 1088 C CD   . PRO A 1 79  ? 141.237 91.570  91.517  1.00 99.99  ? 79  PRO A CD   1 
ATOM 1089 H HA   . PRO A 1 79  ? 139.672 94.001  92.675  1.00 92.67  ? 79  PRO A HA   1 
ATOM 1090 H HB2  . PRO A 1 79  ? 139.927 94.126  90.105  1.00 95.26  ? 79  PRO A HB2  1 
ATOM 1091 H HB3  . PRO A 1 79  ? 141.176 94.318  91.080  1.00 94.32  ? 79  PRO A HB3  1 
ATOM 1092 H HG2  . PRO A 1 79  ? 140.438 92.017  89.680  1.00 95.74  ? 79  PRO A HG2  1 
ATOM 1093 H HG3  . PRO A 1 79  ? 141.907 92.605  89.877  1.00 96.16  ? 79  PRO A HG3  1 
ATOM 1094 H HD2  . PRO A 1 79  ? 141.079 90.640  91.294  1.00 95.09  ? 79  PRO A HD2  1 
ATOM 1095 H HD3  . PRO A 1 79  ? 142.121 91.703  91.894  1.00 93.60  ? 79  PRO A HD3  1 
ATOM 1096 N N    . GLY A 1 80  ? 137.236 93.727  92.362  1.00 89.09  ? 80  GLY A N    1 
ATOM 1097 C CA   . GLY A 1 80  ? 135.826 93.595  92.093  1.00 92.32  ? 80  GLY A CA   1 
ATOM 1098 C C    . GLY A 1 80  ? 135.364 94.532  91.000  1.00 108.52 ? 80  GLY A C    1 
ATOM 1099 O O    . GLY A 1 80  ? 136.129 95.333  90.446  1.00 114.32 ? 80  GLY A O    1 
ATOM 1100 H H    . GLY A 1 80  ? 137.420 94.205  93.053  1.00 92.22  ? 80  GLY A H    1 
ATOM 1101 H HA2  . GLY A 1 80  ? 135.632 92.684  91.821  1.00 92.13  ? 80  GLY A HA2  1 
ATOM 1102 H HA3  . GLY A 1 80  ? 135.323 93.790  92.900  1.00 92.84  ? 80  GLY A HA3  1 
ATOM 1103 N N    . PRO A 1 81  ? 134.077 94.439  90.673  1.00 117.37 ? 81  PRO A N    1 
ATOM 1104 C CA   . PRO A 1 81  ? 133.526 95.291  89.615  1.00 120.30 ? 81  PRO A CA   1 
ATOM 1105 C C    . PRO A 1 81  ? 133.547 96.760  90.005  1.00 120.66 ? 81  PRO A C    1 
ATOM 1106 O O    . PRO A 1 81  ? 133.496 97.119  91.184  1.00 119.14 ? 81  PRO A O    1 
ATOM 1107 C CB   . PRO A 1 81  ? 132.091 94.777  89.452  1.00 115.74 ? 81  PRO A CB   1 
ATOM 1108 C CG   . PRO A 1 81  ? 131.773 94.103  90.743  1.00 114.50 ? 81  PRO A CG   1 
ATOM 1109 C CD   . PRO A 1 81  ? 133.064 93.538  91.248  1.00 111.38 ? 81  PRO A CD   1 
ATOM 1110 H HA   . PRO A 1 81  ? 134.012 95.164  88.785  1.00 117.27 ? 81  PRO A HA   1 
ATOM 1111 H HB2  . PRO A 1 81  ? 131.491 95.524  89.298  1.00 116.44 ? 81  PRO A HB2  1 
ATOM 1112 H HB3  . PRO A 1 81  ? 132.051 94.146  88.716  1.00 114.71 ? 81  PRO A HB3  1 
ATOM 1113 H HG2  . PRO A 1 81  ? 131.418 94.753  91.369  1.00 113.69 ? 81  PRO A HG2  1 
ATOM 1114 H HG3  . PRO A 1 81  ? 131.129 93.394  90.587  1.00 114.44 ? 81  PRO A HG3  1 
ATOM 1115 H HD2  . PRO A 1 81  ? 133.088 93.573  92.217  1.00 111.42 ? 81  PRO A HD2  1 
ATOM 1116 H HD3  . PRO A 1 81  ? 133.189 92.634  90.919  1.00 110.45 ? 81  PRO A HD3  1 
ATOM 1117 N N    . ASN A 1 82  ? 133.629 97.615  88.985  1.00 119.65 ? 82  ASN A N    1 
ATOM 1118 C CA   . ASN A 1 82  ? 133.633 99.066  89.169  1.00 119.40 ? 82  ASN A CA   1 
ATOM 1119 C C    . ASN A 1 82  ? 134.920 99.538  89.845  1.00 117.87 ? 82  ASN A C    1 
ATOM 1120 O O    . ASN A 1 82  ? 134.908 100.473 90.647  1.00 118.42 ? 82  ASN A O    1 
ATOM 1121 C CB   . ASN A 1 82  ? 132.408 99.523  89.966  1.00 115.53 ? 82  ASN A CB   1 
ATOM 1122 C CG   . ASN A 1 82  ? 132.113 101.000 89.787  1.00 116.91 ? 82  ASN A CG   1 
ATOM 1123 O OD1  . ASN A 1 82  ? 132.669 101.654 88.905  1.00 125.43 ? 82  ASN A OD1  1 
ATOM 1124 N ND2  . ASN A 1 82  ? 131.234 101.533 90.627  1.00 109.79 ? 82  ASN A ND2  1 
ATOM 1125 H H    . ASN A 1 82  ? 133.684 97.374  88.161  1.00 118.74 ? 82  ASN A H    1 
ATOM 1126 H HA   . ASN A 1 82  ? 133.590 99.486  88.296  1.00 119.70 ? 82  ASN A HA   1 
ATOM 1127 H HB2  . ASN A 1 82  ? 131.632 99.023  89.668  1.00 116.10 ? 82  ASN A HB2  1 
ATOM 1128 H HB3  . ASN A 1 82  ? 132.565 99.362  90.909  1.00 116.84 ? 82  ASN A HB3  1 
ATOM 1129 H HD21 . ASN A 1 82  ? 131.033 102.367 90.567  1.00 112.53 ? 82  ASN A HD21 1 
ATOM 1130 H HD22 . ASN A 1 82  ? 130.866 101.044 91.231  1.00 112.12 ? 82  ASN A HD22 1 
ATOM 1131 N N    . GLN A 1 83  ? 136.036 98.892  89.514  1.00 113.76 ? 83  GLN A N    1 
ATOM 1132 C CA   . GLN A 1 83  ? 137.352 99.262  90.032  1.00 113.43 ? 83  GLN A CA   1 
ATOM 1133 C C    . GLN A 1 83  ? 137.326 99.377  91.557  1.00 108.51 ? 83  GLN A C    1 
ATOM 1134 O O    . GLN A 1 83  ? 137.566 100.437 92.137  1.00 112.96 ? 83  GLN A O    1 
ATOM 1135 C CB   . GLN A 1 83  ? 137.838 100.567 89.396  1.00 122.09 ? 83  GLN A CB   1 
ATOM 1136 C CG   . GLN A 1 83  ? 138.023 100.499 87.889  1.00 124.46 ? 83  GLN A CG   1 
ATOM 1137 C CD   . GLN A 1 83  ? 138.240 101.866 87.269  1.00 123.79 ? 83  GLN A CD   1 
ATOM 1138 O OE1  . GLN A 1 83  ? 138.439 102.855 87.974  1.00 120.69 ? 83  GLN A OE1  1 
ATOM 1139 N NE2  . GLN A 1 83  ? 138.202 101.929 85.943  1.00 125.51 ? 83  GLN A NE2  1 
ATOM 1140 H H    . GLN A 1 83  ? 136.058 98.221  88.977  1.00 115.95 ? 83  GLN A H    1 
ATOM 1141 H HA   . GLN A 1 83  ? 137.986 98.566  89.799  1.00 114.96 ? 83  GLN A HA   1 
ATOM 1142 H HB2  . GLN A 1 83  ? 137.189 101.264 89.582  1.00 120.55 ? 83  GLN A HB2  1 
ATOM 1143 H HB3  . GLN A 1 83  ? 138.693 100.804 89.788  1.00 120.16 ? 83  GLN A HB3  1 
ATOM 1144 H HG2  . GLN A 1 83  ? 138.799 99.952  87.689  1.00 122.08 ? 83  GLN A HG2  1 
ATOM 1145 H HG3  . GLN A 1 83  ? 137.229 100.110 87.488  1.00 122.59 ? 83  GLN A HG3  1 
ATOM 1146 H HE21 . GLN A 1 83  ? 138.060 101.217 85.483  1.00 124.83 ? 83  GLN A HE21 1 
ATOM 1147 H HE22 . GLN A 1 83  ? 138.319 102.682 85.545  1.00 125.19 ? 83  GLN A HE22 1 
ATOM 1148 N N    . GLY A 1 84  ? 137.027 98.254  92.204  1.00 101.98 ? 84  GLY A N    1 
ATOM 1149 C CA   . GLY A 1 84  ? 136.966 98.204  93.645  1.00 100.93 ? 84  GLY A CA   1 
ATOM 1150 C C    . GLY A 1 84  ? 137.245 96.819  94.190  1.00 96.32  ? 84  GLY A C    1 
ATOM 1151 O O    . GLY A 1 84  ? 137.413 95.852  93.440  1.00 98.68  ? 84  GLY A O    1 
ATOM 1152 H H    . GLY A 1 84  ? 136.855 97.503  91.820  1.00 106.15 ? 84  GLY A H    1 
ATOM 1153 H HA2  . GLY A 1 84  ? 137.617 98.819  94.017  1.00 104.38 ? 84  GLY A HA2  1 
ATOM 1154 H HA3  . GLY A 1 84  ? 136.083 98.477  93.939  1.00 104.44 ? 84  GLY A HA3  1 
ATOM 1155 N N    . PRO A 1 85  ? 137.301 96.698  95.514  1.00 91.98  ? 85  PRO A N    1 
ATOM 1156 C CA   . PRO A 1 85  ? 137.533 95.385  96.124  1.00 89.29  ? 85  PRO A CA   1 
ATOM 1157 C C    . PRO A 1 85  ? 136.251 94.573  96.202  1.00 85.11  ? 85  PRO A C    1 
ATOM 1158 O O    . PRO A 1 85  ? 135.189 95.081  96.572  1.00 84.18  ? 85  PRO A O    1 
ATOM 1159 C CB   . PRO A 1 85  ? 138.058 95.738  97.520  1.00 85.60  ? 85  PRO A CB   1 
ATOM 1160 C CG   . PRO A 1 85  ? 137.418 97.053  97.836  1.00 93.94  ? 85  PRO A CG   1 
ATOM 1161 C CD   . PRO A 1 85  ? 137.147 97.759  96.524  1.00 95.78  ? 85  PRO A CD   1 
ATOM 1162 H HA   . PRO A 1 85  ? 138.212 94.891  95.637  1.00 90.15  ? 85  PRO A HA   1 
ATOM 1163 H HB2  . PRO A 1 85  ? 137.780 95.061  98.156  1.00 85.60  ? 85  PRO A HB2  1 
ATOM 1164 H HB3  . PRO A 1 85  ? 139.025 95.820  97.502  1.00 83.90  ? 85  PRO A HB3  1 
ATOM 1165 H HG2  . PRO A 1 85  ? 136.587 96.896  98.310  1.00 90.96  ? 85  PRO A HG2  1 
ATOM 1166 H HG3  . PRO A 1 85  ? 138.022 97.580  98.382  1.00 92.89  ? 85  PRO A HG3  1 
ATOM 1167 H HD2  . PRO A 1 85  ? 136.243 98.111  96.508  1.00 94.08  ? 85  PRO A HD2  1 
ATOM 1168 H HD3  . PRO A 1 85  ? 137.803 98.459  96.381  1.00 95.88  ? 85  PRO A HD3  1 
ATOM 1169 N N    . HIS A 1 86  ? 136.360 93.293  95.852  1.00 73.78  ? 86  HIS A N    1 
ATOM 1170 C CA   . HIS A 1 86  ? 135.186 92.433  95.821  1.00 70.52  ? 86  HIS A CA   1 
ATOM 1171 C C    . HIS A 1 86  ? 134.592 92.301  97.218  1.00 67.79  ? 86  HIS A C    1 
ATOM 1172 O O    . HIS A 1 86  ? 135.305 92.050  98.193  1.00 71.01  ? 86  HIS A O    1 
ATOM 1173 C CB   . HIS A 1 86  ? 135.549 91.061  95.252  1.00 74.46  ? 86  HIS A CB   1 
ATOM 1174 C CG   . HIS A 1 86  ? 134.362 90.236  94.862  1.00 77.22  ? 86  HIS A CG   1 
ATOM 1175 N ND1  . HIS A 1 86  ? 133.068 90.702  94.959  1.00 71.81  ? 86  HIS A ND1  1 
ATOM 1176 C CD2  . HIS A 1 86  ? 134.274 88.986  94.348  1.00 73.56  ? 86  HIS A CD2  1 
ATOM 1177 C CE1  . HIS A 1 86  ? 132.234 89.766  94.543  1.00 67.34  ? 86  HIS A CE1  1 
ATOM 1178 N NE2  . HIS A 1 86  ? 132.939 88.714  94.169  1.00 69.93  ? 86  HIS A NE2  1 
ATOM 1179 H H    . HIS A 1 86  ? 137.098 92.906  95.637  1.00 79.55  ? 86  HIS A H    1 
ATOM 1180 H HA   . HIS A 1 86  ? 134.515 92.833  95.247  1.00 77.03  ? 86  HIS A HA   1 
ATOM 1181 H HB2  . HIS A 1 86  ? 136.086 91.198  94.457  1.00 76.76  ? 86  HIS A HB2  1 
ATOM 1182 H HB3  . HIS A 1 86  ? 136.053 90.564  95.917  1.00 74.83  ? 86  HIS A HB3  1 
ATOM 1183 H HD2  . HIS A 1 86  ? 134.986 88.413  94.176  1.00 74.85  ? 86  HIS A HD2  1 
ATOM 1184 H HE1  . HIS A 1 86  ? 131.309 89.837  94.515  1.00 67.96  ? 86  HIS A HE1  1 
ATOM 1185 H HE2  . HIS A 1 86  ? 132.611 87.979  93.859  1.00 71.42  ? 86  HIS A HE2  1 
ATOM 1186 N N    . GLN A 1 87  ? 133.272 92.462  97.301  1.00 63.56  ? 87  GLN A N    1 
ATOM 1187 C CA   . GLN A 1 87  ? 132.594 92.628  98.581  1.00 60.21  ? 87  GLN A CA   1 
ATOM 1188 C C    . GLN A 1 87  ? 132.445 91.321  99.352  1.00 64.19  ? 87  GLN A C    1 
ATOM 1189 O O    . GLN A 1 87  ? 132.362 91.347  100.585 1.00 70.64  ? 87  GLN A O    1 
ATOM 1190 C CB   . GLN A 1 87  ? 131.216 93.246  98.342  1.00 54.54  ? 87  GLN A CB   1 
ATOM 1191 C CG   . GLN A 1 87  ? 131.262 94.667  97.798  1.00 57.47  ? 87  GLN A CG   1 
ATOM 1192 C CD   . GLN A 1 87  ? 130.528 95.656  98.678  1.00 66.27  ? 87  GLN A CD   1 
ATOM 1193 O OE1  . GLN A 1 87  ? 129.473 95.345  99.228  1.00 72.07  ? 87  GLN A OE1  1 
ATOM 1194 N NE2  . GLN A 1 87  ? 131.074 96.860  98.802  1.00 64.13  ? 87  GLN A NE2  1 
ATOM 1195 H H    . GLN A 1 87  ? 132.745 92.483  96.623  1.00 66.33  ? 87  GLN A H    1 
ATOM 1196 H HA   . GLN A 1 87  ? 133.106 93.238  99.133  1.00 61.20  ? 87  GLN A HA   1 
ATOM 1197 H HB2  . GLN A 1 87  ? 130.736 92.699  97.701  1.00 59.99  ? 87  GLN A HB2  1 
ATOM 1198 H HB3  . GLN A 1 87  ? 130.735 93.264  99.184  1.00 56.17  ? 87  GLN A HB3  1 
ATOM 1199 H HG2  . GLN A 1 87  ? 132.188 94.951  97.742  1.00 61.09  ? 87  GLN A HG2  1 
ATOM 1200 H HG3  . GLN A 1 87  ? 130.856 94.685  96.917  1.00 61.30  ? 87  GLN A HG3  1 
ATOM 1201 H HE21 . GLN A 1 87  ? 131.811 97.044  98.399  1.00 62.59  ? 87  GLN A HE21 1 
ATOM 1202 H HE22 . GLN A 1 87  ? 130.691 97.456  99.290  1.00 59.07  ? 87  GLN A HE22 1 
ATOM 1203 N N    . CYS A 1 88  ? 132.400 90.182  98.662  1.00 61.59  ? 88  CYS A N    1 
ATOM 1204 C CA   . CYS A 1 88  ? 132.080 88.905  99.297  1.00 60.39  ? 88  CYS A CA   1 
ATOM 1205 C C    . CYS A 1 88  ? 133.028 87.810  98.831  1.00 62.92  ? 88  CYS A C    1 
ATOM 1206 O O    . CYS A 1 88  ? 132.604 86.689  98.531  1.00 72.76  ? 88  CYS A O    1 
ATOM 1207 C CB   . CYS A 1 88  ? 130.635 88.501  99.012  1.00 67.54  ? 88  CYS A CB   1 
ATOM 1208 S SG   . CYS A 1 88  ? 129.434 89.831  99.213  1.00 84.45  ? 88  CYS A SG   1 
ATOM 1209 H H    . CYS A 1 88  ? 132.556 90.122  97.819  1.00 65.29  ? 88  CYS A H    1 
ATOM 1210 H HA   . CYS A 1 88  ? 132.180 88.995  100.257 1.00 62.08  ? 88  CYS A HA   1 
ATOM 1211 H HB2  . CYS A 1 88  ? 130.575 88.191  98.095  1.00 67.71  ? 88  CYS A HB2  1 
ATOM 1212 H HB3  . CYS A 1 88  ? 130.385 87.783  99.615  1.00 67.83  ? 88  CYS A HB3  1 
ATOM 1213 N N    . ARG A 1 89  ? 134.324 88.107  98.767  1.00 59.94  ? 89  ARG A N    1 
ATOM 1214 C CA   . ARG A 1 89  ? 135.298 87.105  98.368  1.00 64.88  ? 89  ARG A CA   1 
ATOM 1215 C C    . ARG A 1 89  ? 136.640 87.425  99.008  1.00 65.56  ? 89  ARG A C    1 
ATOM 1216 O O    . ARG A 1 89  ? 136.846 88.506  99.566  1.00 75.19  ? 89  ARG A O    1 
ATOM 1217 C CB   . ARG A 1 89  ? 135.462 87.041  96.847  1.00 72.31  ? 89  ARG A CB   1 
ATOM 1218 C CG   . ARG A 1 89  ? 134.522 86.088  96.130  1.00 76.08  ? 89  ARG A CG   1 
ATOM 1219 C CD   . ARG A 1 89  ? 134.933 84.632  96.286  1.00 75.97  ? 89  ARG A CD   1 
ATOM 1220 N NE   . ARG A 1 89  ? 134.062 83.741  95.529  1.00 75.01  ? 89  ARG A NE   1 
ATOM 1221 C CZ   . ARG A 1 89  ? 132.789 83.500  95.813  1.00 74.04  ? 89  ARG A CZ   1 
ATOM 1222 N NH1  . ARG A 1 89  ? 132.194 84.054  96.857  1.00 70.33  ? 89  ARG A NH1  1 
ATOM 1223 N NH2  . ARG A 1 89  ? 132.094 82.683  95.027  1.00 79.73  ? 89  ARG A NH2  1 
ATOM 1224 H H    . ARG A 1 89  ? 134.665 88.876  98.941  1.00 64.30  ? 89  ARG A H    1 
ATOM 1225 H HA   . ARG A 1 89  ? 135.001 86.239  98.687  1.00 66.87  ? 89  ARG A HA   1 
ATOM 1226 H HB2  . ARG A 1 89  ? 135.318 87.932  96.499  1.00 71.07  ? 89  ARG A HB2  1 
ATOM 1227 H HB3  . ARG A 1 89  ? 136.363 86.756  96.634  1.00 72.29  ? 89  ARG A HB3  1 
ATOM 1228 H HG2  . ARG A 1 89  ? 133.625 86.201  96.481  1.00 72.08  ? 89  ARG A HG2  1 
ATOM 1229 H HG3  . ARG A 1 89  ? 134.540 86.292  95.184  1.00 74.11  ? 89  ARG A HG3  1 
ATOM 1230 H HD2  . ARG A 1 89  ? 135.840 84.514  95.966  1.00 73.24  ? 89  ARG A HD2  1 
ATOM 1231 H HD3  . ARG A 1 89  ? 134.871 84.384  97.221  1.00 73.81  ? 89  ARG A HD3  1 
ATOM 1232 H HE   . ARG A 1 89  ? 134.376 83.407  94.801  1.00 74.34  ? 89  ARG A HE   1 
ATOM 1233 H HH11 . ARG A 1 89  ? 132.629 84.584  97.374  1.00 71.49  ? 89  ARG A HH11 1 
ATOM 1234 H HH12 . ARG A 1 89  ? 131.367 83.879  97.018  1.00 71.08  ? 89  ARG A HH12 1 
ATOM 1235 H HH21 . ARG A 1 89  ? 132.471 82.318  94.345  1.00 79.14  ? 89  ARG A HH21 1 
ATOM 1236 H HH22 . ARG A 1 89  ? 131.269 82.519  95.201  1.00 77.97  ? 89  ARG A HH22 1 
ATOM 1237 N N    . ARG A 1 90  ? 137.552 86.461  98.922  1.00 60.89  ? 90  ARG A N    1 
ATOM 1238 C CA   . ARG A 1 90  ? 138.912 86.641  99.406  1.00 61.06  ? 90  ARG A CA   1 
ATOM 1239 C C    . ARG A 1 90  ? 139.802 85.614  98.721  1.00 65.00  ? 90  ARG A C    1 
ATOM 1240 O O    . ARG A 1 90  ? 139.351 84.529  98.345  1.00 74.77  ? 90  ARG A O    1 
ATOM 1241 C CB   . ARG A 1 90  ? 138.977 86.509  100.933 1.00 61.88  ? 90  ARG A CB   1 
ATOM 1242 C CG   . ARG A 1 90  ? 140.233 85.844  101.467 1.00 68.51  ? 90  ARG A CG   1 
ATOM 1243 C CD   . ARG A 1 90  ? 140.451 86.151  102.934 1.00 70.86  ? 90  ARG A CD   1 
ATOM 1244 N NE   . ARG A 1 90  ? 141.054 85.021  103.629 1.00 74.93  ? 90  ARG A NE   1 
ATOM 1245 C CZ   . ARG A 1 90  ? 142.305 84.619  103.455 1.00 72.89  ? 90  ARG A CZ   1 
ATOM 1246 N NH1  . ARG A 1 90  ? 143.117 85.232  102.609 1.00 64.13  ? 90  ARG A NH1  1 
ATOM 1247 N NH2  . ARG A 1 90  ? 142.752 83.572  104.142 1.00 74.86  ? 90  ARG A NH2  1 
ATOM 1248 H H    . ARG A 1 90  ? 137.403 85.686  98.580  1.00 65.07  ? 90  ARG A H    1 
ATOM 1249 H HA   . ARG A 1 90  ? 139.225 87.526  99.164  1.00 65.73  ? 90  ARG A HA   1 
ATOM 1250 H HB2  . ARG A 1 90  ? 138.930 87.397  101.323 1.00 65.78  ? 90  ARG A HB2  1 
ATOM 1251 H HB3  . ARG A 1 90  ? 138.218 85.983  101.231 1.00 62.45  ? 90  ARG A HB3  1 
ATOM 1252 H HG2  . ARG A 1 90  ? 140.160 84.883  101.362 1.00 68.72  ? 90  ARG A HG2  1 
ATOM 1253 H HG3  . ARG A 1 90  ? 141.007 86.180  100.991 1.00 67.84  ? 90  ARG A HG3  1 
ATOM 1254 H HD2  . ARG A 1 90  ? 141.045 86.913  103.016 1.00 68.99  ? 90  ARG A HD2  1 
ATOM 1255 H HD3  . ARG A 1 90  ? 139.598 86.344  103.352 1.00 70.08  ? 90  ARG A HD3  1 
ATOM 1256 H HE   . ARG A 1 90  ? 140.560 84.574  104.173 1.00 72.33  ? 90  ARG A HE   1 
ATOM 1257 H HH11 . ARG A 1 90  ? 142.841 85.910  102.157 1.00 65.49  ? 90  ARG A HH11 1 
ATOM 1258 H HH12 . ARG A 1 90  ? 143.924 84.952  102.511 1.00 65.86  ? 90  ARG A HH12 1 
ATOM 1259 H HH21 . ARG A 1 90  ? 142.232 83.166  104.693 1.00 72.87  ? 90  ARG A HH21 1 
ATOM 1260 H HH22 . ARG A 1 90  ? 143.562 83.303  104.035 1.00 74.10  ? 90  ARG A HH22 1 
ATOM 1261 N N    . PHE A 1 91  ? 141.076 85.967  98.569  1.00 66.39  ? 91  PHE A N    1 
ATOM 1262 C CA   . PHE A 1 91  ? 142.037 85.050  97.971  1.00 70.82  ? 91  PHE A CA   1 
ATOM 1263 C C    . PHE A 1 91  ? 142.280 83.864  98.895  1.00 76.98  ? 91  PHE A C    1 
ATOM 1264 O O    . PHE A 1 91  ? 142.387 84.017  100.114 1.00 82.76  ? 91  PHE A O    1 
ATOM 1265 C CB   . PHE A 1 91  ? 143.360 85.763  97.689  1.00 79.87  ? 91  PHE A CB   1 
ATOM 1266 C CG   . PHE A 1 91  ? 143.442 86.381  96.323  1.00 82.94  ? 91  PHE A CG   1 
ATOM 1267 C CD1  . PHE A 1 91  ? 142.949 87.653  96.094  1.00 78.07  ? 91  PHE A CD1  1 
ATOM 1268 C CD2  . PHE A 1 91  ? 144.012 85.690  95.269  1.00 85.18  ? 91  PHE A CD2  1 
ATOM 1269 C CE1  . PHE A 1 91  ? 143.026 88.225  94.839  1.00 75.57  ? 91  PHE A CE1  1 
ATOM 1270 C CE2  . PHE A 1 91  ? 144.090 86.256  94.011  1.00 84.45  ? 91  PHE A CE2  1 
ATOM 1271 C CZ   . PHE A 1 91  ? 143.596 87.525  93.797  1.00 82.13  ? 91  PHE A CZ   1 
ATOM 1272 H H    . PHE A 1 91  ? 141.406 86.726  98.805  1.00 71.15  ? 91  PHE A H    1 
ATOM 1273 H HA   . PHE A 1 91  ? 141.683 84.718  97.131  1.00 72.74  ? 91  PHE A HA   1 
ATOM 1274 H HB2  . PHE A 1 91  ? 143.482 86.470  98.342  1.00 77.36  ? 91  PHE A HB2  1 
ATOM 1275 H HB3  . PHE A 1 91  ? 144.083 85.120  97.764  1.00 77.85  ? 91  PHE A HB3  1 
ATOM 1276 H HD1  . PHE A 1 91  ? 142.565 88.130  96.793  1.00 77.43  ? 91  PHE A HD1  1 
ATOM 1277 H HD2  . PHE A 1 91  ? 144.347 84.834  95.408  1.00 82.11  ? 91  PHE A HD2  1 
ATOM 1278 H HE1  . PHE A 1 91  ? 142.692 89.080  94.698  1.00 79.22  ? 91  PHE A HE1  1 
ATOM 1279 H HE2  . PHE A 1 91  ? 144.475 85.781  93.310  1.00 84.03  ? 91  PHE A HE2  1 
ATOM 1280 H HZ   . PHE A 1 91  ? 143.647 87.909  92.951  1.00 81.99  ? 91  PHE A HZ   1 
ATOM 1281 N N    . ARG A 1 92  ? 142.368 82.671  98.304  1.00 86.39  ? 92  ARG A N    1 
ATOM 1282 C CA   . ARG A 1 92  ? 142.651 81.481  99.100  1.00 96.26  ? 92  ARG A CA   1 
ATOM 1283 C C    . ARG A 1 92  ? 144.023 81.578  99.755  1.00 95.77  ? 92  ARG A C    1 
ATOM 1284 O O    . ARG A 1 92  ? 144.186 81.224  100.928 1.00 99.75  ? 92  ARG A O    1 
ATOM 1285 C CB   . ARG A 1 92  ? 142.556 80.232  98.224  1.00 99.48  ? 92  ARG A CB   1 
ATOM 1286 C CG   . ARG A 1 92  ? 142.415 78.935  99.006  1.00 96.79  ? 92  ARG A CG   1 
ATOM 1287 C CD   . ARG A 1 92  ? 142.115 77.761  98.087  1.00 98.02  ? 92  ARG A CD   1 
ATOM 1288 N NE   . ARG A 1 92  ? 140.793 77.868  97.480  1.00 101.15 ? 92  ARG A NE   1 
ATOM 1289 C CZ   . ARG A 1 92  ? 139.693 77.293  97.951  1.00 102.56 ? 92  ARG A CZ   1 
ATOM 1290 N NH1  . ARG A 1 92  ? 139.712 76.552  99.047  1.00 103.85 ? 92  ARG A NH1  1 
ATOM 1291 N NH2  . ARG A 1 92  ? 138.544 77.467  97.305  1.00 100.96 ? 92  ARG A NH2  1 
ATOM 1292 H H    . ARG A 1 92  ? 142.269 82.527  97.462  1.00 85.44  ? 92  ARG A H    1 
ATOM 1293 H HA   . ARG A 1 92  ? 141.988 81.406  99.803  1.00 92.21  ? 92  ARG A HA   1 
ATOM 1294 H HB2  . ARG A 1 92  ? 141.781 80.315  97.646  1.00 97.00  ? 92  ARG A HB2  1 
ATOM 1295 H HB3  . ARG A 1 92  ? 143.360 80.166  97.686  1.00 98.59  ? 92  ARG A HB3  1 
ATOM 1296 H HG2  . ARG A 1 92  ? 143.245 78.751  99.473  1.00 96.90  ? 92  ARG A HG2  1 
ATOM 1297 H HG3  . ARG A 1 92  ? 141.685 79.020  99.639  1.00 97.53  ? 92  ARG A HG3  1 
ATOM 1298 H HD2  . ARG A 1 92  ? 142.770 77.747  97.371  1.00 98.68  ? 92  ARG A HD2  1 
ATOM 1299 H HD3  . ARG A 1 92  ? 142.164 76.935  98.592  1.00 97.73  ? 92  ARG A HD3  1 
ATOM 1300 H HE   . ARG A 1 92  ? 140.714 78.366  96.783  1.00 101.06 ? 92  ARG A HE   1 
ATOM 1301 H HH11 . ARG A 1 92  ? 140.445 76.429  99.478  1.00 101.69 ? 92  ARG A HH11 1 
ATOM 1302 H HH12 . ARG A 1 92  ? 138.984 76.191  99.331  1.00 104.58 ? 92  ARG A HH12 1 
ATOM 1303 H HH21 . ARG A 1 92  ? 138.519 77.947  96.592  1.00 101.32 ? 92  ARG A HH21 1 
ATOM 1304 H HH22 . ARG A 1 92  ? 137.825 77.100  97.601  1.00 102.90 ? 92  ARG A HH22 1 
ATOM 1305 N N    . GLN A 1 93  ? 145.017 82.057  99.015  1.00 95.55  ? 93  GLN A N    1 
ATOM 1306 C CA   . GLN A 1 93  ? 146.366 82.251  99.524  1.00 102.36 ? 93  GLN A CA   1 
ATOM 1307 C C    . GLN A 1 93  ? 146.881 83.598  99.045  1.00 109.21 ? 93  GLN A C    1 
ATOM 1308 O O    . GLN A 1 93  ? 146.443 84.097  98.002  1.00 106.33 ? 93  GLN A O    1 
ATOM 1309 C CB   . GLN A 1 93  ? 147.321 81.142  99.052  1.00 102.49 ? 93  GLN A CB   1 
ATOM 1310 C CG   . GLN A 1 93  ? 146.631 79.864  98.600  1.00 104.66 ? 93  GLN A CG   1 
ATOM 1311 C CD   . GLN A 1 93  ? 147.610 78.829  98.083  1.00 111.38 ? 93  GLN A CD   1 
ATOM 1312 O OE1  . GLN A 1 93  ? 148.802 78.879  98.385  1.00 110.80 ? 93  GLN A OE1  1 
ATOM 1313 N NE2  . GLN A 1 93  ? 147.110 77.884  97.295  1.00 114.53 ? 93  GLN A NE2  1 
ATOM 1314 H H    . GLN A 1 93  ? 144.930 82.284  98.190  1.00 95.12  ? 93  GLN A H    1 
ATOM 1315 H HA   . GLN A 1 93  ? 146.345 82.248  100.493 1.00 100.64 ? 93  GLN A HA   1 
ATOM 1316 H HB2  . GLN A 1 93  ? 147.839 81.477  98.304  1.00 104.14 ? 93  GLN A HB2  1 
ATOM 1317 H HB3  . GLN A 1 93  ? 147.916 80.913  99.783  1.00 102.63 ? 93  GLN A HB3  1 
ATOM 1318 H HG2  . GLN A 1 93  ? 146.152 79.479  99.350  1.00 103.62 ? 93  GLN A HG2  1 
ATOM 1319 H HG3  . GLN A 1 93  ? 146.015 80.070  97.880  1.00 104.11 ? 93  GLN A HG3  1 
ATOM 1320 H HE21 . GLN A 1 93  ? 146.271 77.882  97.105  1.00 110.51 ? 93  GLN A HE21 1 
ATOM 1321 H HE22 . GLN A 1 93  ? 147.625 77.274  96.975  1.00 113.24 ? 93  GLN A HE22 1 
ATOM 1322 N N    . PRO A 1 94  ? 147.807 84.210  99.782  1.00 113.39 ? 94  PRO A N    1 
ATOM 1323 C CA   . PRO A 1 94  ? 148.377 85.481  99.322  1.00 110.80 ? 94  PRO A CA   1 
ATOM 1324 C C    . PRO A 1 94  ? 149.137 85.300  98.017  1.00 111.13 ? 94  PRO A C    1 
ATOM 1325 O O    . PRO A 1 94  ? 149.760 84.264  97.772  1.00 106.76 ? 94  PRO A O    1 
ATOM 1326 C CB   . PRO A 1 94  ? 149.310 85.892  100.467 1.00 111.37 ? 94  PRO A CB   1 
ATOM 1327 C CG   . PRO A 1 94  ? 149.629 84.624  101.176 1.00 107.48 ? 94  PRO A CG   1 
ATOM 1328 C CD   . PRO A 1 94  ? 148.414 83.756  101.045 1.00 105.26 ? 94  PRO A CD   1 
ATOM 1329 H HA   . PRO A 1 94  ? 147.683 86.149  99.211  1.00 103.10 ? 94  PRO A HA   1 
ATOM 1330 H HB2  . PRO A 1 94  ? 150.114 86.295  100.105 1.00 109.46 ? 94  PRO A HB2  1 
ATOM 1331 H HB3  . PRO A 1 94  ? 148.850 86.509  101.058 1.00 106.69 ? 94  PRO A HB3  1 
ATOM 1332 H HG2  . PRO A 1 94  ? 150.395 84.202  100.755 1.00 107.36 ? 94  PRO A HG2  1 
ATOM 1333 H HG3  . PRO A 1 94  ? 149.814 84.812  102.109 1.00 108.01 ? 94  PRO A HG3  1 
ATOM 1334 H HD2  . PRO A 1 94  ? 148.672 82.824  100.981 1.00 105.86 ? 94  PRO A HD2  1 
ATOM 1335 H HD3  . PRO A 1 94  ? 147.808 83.911  101.786 1.00 105.25 ? 94  PRO A HD3  1 
ATOM 1336 N N    . GLN A 1 95  ? 149.076 86.328  97.173  1.00 110.80 ? 95  GLN A N    1 
ATOM 1337 C CA   . GLN A 1 95  ? 149.740 86.325  95.870  1.00 112.79 ? 95  GLN A CA   1 
ATOM 1338 C C    . GLN A 1 95  ? 150.598 87.582  95.775  1.00 116.91 ? 95  GLN A C    1 
ATOM 1339 O O    . GLN A 1 95  ? 150.088 88.670  95.490  1.00 115.02 ? 95  GLN A O    1 
ATOM 1340 C CB   . GLN A 1 95  ? 148.726 86.258  94.732  1.00 109.49 ? 95  GLN A CB   1 
ATOM 1341 C CG   . GLN A 1 95  ? 147.493 85.421  95.042  1.00 100.96 ? 95  GLN A CG   1 
ATOM 1342 C CD   . GLN A 1 95  ? 146.986 84.656  93.835  1.00 100.48 ? 95  GLN A CD   1 
ATOM 1343 O OE1  . GLN A 1 95  ? 147.375 84.932  92.700  1.00 103.99 ? 95  GLN A OE1  1 
ATOM 1344 N NE2  . GLN A 1 95  ? 146.116 83.682  94.076  1.00 98.15  ? 95  GLN A NE2  1 
ATOM 1345 H H    . GLN A 1 95  ? 148.647 87.055  97.336  1.00 105.76 ? 95  GLN A H    1 
ATOM 1346 H HA   . GLN A 1 95  ? 150.324 85.553  95.804  1.00 110.49 ? 95  GLN A HA   1 
ATOM 1347 H HB2  . GLN A 1 95  ? 148.427 87.157  94.526  1.00 105.19 ? 95  GLN A HB2  1 
ATOM 1348 H HB3  . GLN A 1 95  ? 149.161 85.872  93.956  1.00 108.71 ? 95  GLN A HB3  1 
ATOM 1349 H HG2  . GLN A 1 95  ? 147.711 84.774  95.731  1.00 102.50 ? 95  GLN A HG2  1 
ATOM 1350 H HG3  . GLN A 1 95  ? 146.784 86.007  95.349  1.00 98.21  ? 95  GLN A HG3  1 
ATOM 1351 H HE21 . GLN A 1 95  ? 145.868 83.517  94.882  1.00 97.71  ? 95  GLN A HE21 1 
ATOM 1352 H HE22 . GLN A 1 95  ? 145.799 83.218  93.425  1.00 98.48  ? 95  GLN A HE22 1 
ATOM 1353 N N    . TRP A 1 96  ? 151.902 87.430  96.010  1.00 121.01 ? 96  TRP A N    1 
ATOM 1354 C CA   . TRP A 1 96  ? 152.819 88.559  95.923  1.00 124.61 ? 96  TRP A CA   1 
ATOM 1355 C C    . TRP A 1 96  ? 153.049 89.020  94.490  1.00 126.47 ? 96  TRP A C    1 
ATOM 1356 O O    . TRP A 1 96  ? 153.562 90.126  94.290  1.00 128.42 ? 96  TRP A O    1 
ATOM 1357 C CB   . TRP A 1 96  ? 154.157 88.194  96.568  1.00 125.39 ? 96  TRP A CB   1 
ATOM 1358 C CG   . TRP A 1 96  ? 154.013 87.578  97.925  1.00 127.44 ? 96  TRP A CG   1 
ATOM 1359 C CD1  . TRP A 1 96  ? 154.331 86.300  98.282  1.00 125.54 ? 96  TRP A CD1  1 
ATOM 1360 C CD2  . TRP A 1 96  ? 153.509 88.211  99.107  1.00 126.94 ? 96  TRP A CD2  1 
ATOM 1361 N NE1  . TRP A 1 96  ? 154.058 86.099  99.613  1.00 126.37 ? 96  TRP A NE1  1 
ATOM 1362 C CE2  . TRP A 1 96  ? 153.552 87.257  100.142 1.00 123.46 ? 96  TRP A CE2  1 
ATOM 1363 C CE3  . TRP A 1 96  ? 153.026 89.493  99.390  1.00 121.91 ? 96  TRP A CE3  1 
ATOM 1364 C CZ2  . TRP A 1 96  ? 153.132 87.543  101.439 1.00 119.23 ? 96  TRP A CZ2  1 
ATOM 1365 C CZ3  . TRP A 1 96  ? 152.609 89.775  100.679 1.00 116.47 ? 96  TRP A CZ3  1 
ATOM 1366 C CH2  . TRP A 1 96  ? 152.665 88.804  101.687 1.00 116.04 ? 96  TRP A CH2  1 
ATOM 1367 H H    . TRP A 1 96  ? 152.276 86.684  96.217  1.00 119.75 ? 96  TRP A H    1 
ATOM 1368 H HA   . TRP A 1 96  ? 152.445 89.305  96.418  1.00 121.54 ? 96  TRP A HA   1 
ATOM 1369 H HB2  . TRP A 1 96  ? 154.616 87.557  95.998  1.00 124.78 ? 96  TRP A HB2  1 
ATOM 1370 H HB3  . TRP A 1 96  ? 154.691 88.998  96.660  1.00 124.90 ? 96  TRP A HB3  1 
ATOM 1371 H HD1  . TRP A 1 96  ? 154.682 85.659  97.707  1.00 124.19 ? 96  TRP A HD1  1 
ATOM 1372 H HE1  . TRP A 1 96  ? 154.184 85.365  100.044 1.00 124.54 ? 96  TRP A HE1  1 
ATOM 1373 H HE3  . TRP A 1 96  ? 152.986 90.142  98.726  1.00 119.35 ? 96  TRP A HE3  1 
ATOM 1374 H HZ2  . TRP A 1 96  ? 153.168 86.901  102.111 1.00 120.54 ? 96  TRP A HZ2  1 
ATOM 1375 H HZ3  . TRP A 1 96  ? 152.286 90.624  100.879 1.00 112.47 ? 96  TRP A HZ3  1 
ATOM 1376 H HH2  . TRP A 1 96  ? 152.378 89.022  102.544 1.00 114.10 ? 96  TRP A HH2  1 
ATOM 1377 N N    . GLN A 1 97  ? 152.676 88.211  93.496  1.00 125.20 ? 97  GLN A N    1 
ATOM 1378 C CA   . GLN A 1 97  ? 152.876 88.615  92.108  1.00 122.01 ? 97  GLN A CA   1 
ATOM 1379 C C    . GLN A 1 97  ? 152.063 89.862  91.788  1.00 123.88 ? 97  GLN A C    1 
ATOM 1380 O O    . GLN A 1 97  ? 152.527 90.746  91.057  1.00 122.57 ? 97  GLN A O    1 
ATOM 1381 C CB   . GLN A 1 97  ? 152.515 87.485  91.132  1.00 119.97 ? 97  GLN A CB   1 
ATOM 1382 C CG   . GLN A 1 97  ? 152.908 86.042  91.513  1.00 121.12 ? 97  GLN A CG   1 
ATOM 1383 C CD   . GLN A 1 97  ? 152.067 85.427  92.621  1.00 123.37 ? 97  GLN A CD   1 
ATOM 1384 O OE1  . GLN A 1 97  ? 151.784 86.064  93.633  1.00 127.04 ? 97  GLN A OE1  1 
ATOM 1385 N NE2  . GLN A 1 97  ? 151.663 84.177  92.429  1.00 120.75 ? 97  GLN A NE2  1 
ATOM 1386 H H    . GLN A 1 97  ? 152.299 87.459  93.608  1.00 123.38 ? 97  GLN A H    1 
ATOM 1387 H HA   . GLN A 1 97  ? 153.813 88.831  91.977  1.00 123.36 ? 97  GLN A HA   1 
ATOM 1388 H HB2  . GLN A 1 97  ? 151.552 87.492  91.010  1.00 120.55 ? 97  GLN A HB2  1 
ATOM 1389 H HB3  . GLN A 1 97  ? 152.942 87.678  90.282  1.00 122.11 ? 97  GLN A HB3  1 
ATOM 1390 H HG2  . GLN A 1 97  ? 152.815 85.479  90.728  1.00 121.64 ? 97  GLN A HG2  1 
ATOM 1391 H HG3  . GLN A 1 97  ? 153.832 86.040  91.809  1.00 121.84 ? 97  GLN A HG3  1 
ATOM 1392 H HE21 . GLN A 1 97  ? 151.880 83.761  91.708  1.00 121.00 ? 97  GLN A HE21 1 
ATOM 1393 H HE22 . GLN A 1 97  ? 151.185 83.782  93.025  1.00 119.07 ? 97  GLN A HE22 1 
ATOM 1394 N N    . LEU A 1 98  ? 150.845 89.952  92.325  1.00 123.03 ? 98  LEU A N    1 
ATOM 1395 C CA   . LEU A 1 98  ? 150.025 91.140  92.140  1.00 123.79 ? 98  LEU A CA   1 
ATOM 1396 C C    . LEU A 1 98  ? 150.586 92.358  92.862  1.00 133.41 ? 98  LEU A C    1 
ATOM 1397 O O    . LEU A 1 98  ? 150.114 93.473  92.616  1.00 135.90 ? 98  LEU A O    1 
ATOM 1398 C CB   . LEU A 1 98  ? 148.599 90.869  92.623  1.00 110.07 ? 98  LEU A CB   1 
ATOM 1399 H H    . LEU A 1 98  ? 150.475 89.337  92.799  1.00 121.60 ? 98  LEU A H    1 
ATOM 1400 H HA   . LEU A 1 98  ? 149.984 91.349  91.193  1.00 123.49 ? 98  LEU A HA   1 
ATOM 1401 N N    . LEU A 1 99  ? 151.574 92.174  93.742  1.00 137.56 ? 99  LEU A N    1 
ATOM 1402 C CA   . LEU A 1 99  ? 152.148 93.312  94.454  1.00 131.09 ? 99  LEU A CA   1 
ATOM 1403 C C    . LEU A 1 99  ? 152.812 94.288  93.490  1.00 135.36 ? 99  LEU A C    1 
ATOM 1404 O O    . LEU A 1 99  ? 152.676 95.508  93.640  1.00 135.72 ? 99  LEU A O    1 
ATOM 1405 C CB   . LEU A 1 99  ? 153.154 92.822  95.495  1.00 121.35 ? 99  LEU A CB   1 
ATOM 1406 H H    . LEU A 1 99  ? 151.923 91.414  93.942  1.00 129.57 ? 99  LEU A H    1 
ATOM 1407 H HA   . LEU A 1 99  ? 151.440 93.784  94.919  1.00 127.52 ? 99  LEU A HA   1 
ATOM 1408 N N    . ASP A 1 100 ? 153.528 93.775  92.499  1.00 134.16 ? 100 ASP A N    1 
ATOM 1409 C CA   . ASP A 1 100 ? 154.221 94.637  91.549  1.00 133.23 ? 100 ASP A CA   1 
ATOM 1410 C C    . ASP A 1 100 ? 153.210 95.365  90.673  1.00 144.83 ? 100 ASP A C    1 
ATOM 1411 O O    . ASP A 1 100 ? 152.411 94.710  89.991  1.00 146.37 ? 100 ASP A O    1 
ATOM 1412 C CB   . ASP A 1 100 ? 155.174 93.814  90.687  1.00 124.87 ? 100 ASP A CB   1 
ATOM 1413 H H    . ASP A 1 100 ? 153.630 92.934  92.355  1.00 132.19 ? 100 ASP A H    1 
ATOM 1414 H HA   . ASP A 1 100 ? 154.740 95.299  92.033  1.00 133.23 ? 100 ASP A HA   1 
ATOM 1415 N N    . PRO A 1 101 ? 153.203 96.699  90.655  1.00 148.92 ? 101 PRO A N    1 
ATOM 1416 C CA   . PRO A 1 101 ? 152.226 97.412  89.817  1.00 143.00 ? 101 PRO A CA   1 
ATOM 1417 C C    . PRO A 1 101 ? 152.393 97.154  88.330  1.00 146.07 ? 101 PRO A C    1 
ATOM 1418 O O    . PRO A 1 101 ? 151.430 97.335  87.575  1.00 147.26 ? 101 PRO A O    1 
ATOM 1419 C CB   . PRO A 1 101 ? 152.478 98.886  90.161  1.00 137.10 ? 101 PRO A CB   1 
ATOM 1420 H HA   . PRO A 1 101 ? 151.324 97.174  90.082  1.00 142.32 ? 101 PRO A HA   1 
ATOM 1421 N N    . ASN A 1 102 ? 153.581 96.740  87.883  1.00 147.68 ? 102 ASN A N    1 
ATOM 1422 C CA   . ASN A 1 102 ? 153.815 96.562  86.454  1.00 150.23 ? 102 ASN A CA   1 
ATOM 1423 C C    . ASN A 1 102 ? 152.896 95.493  85.873  1.00 149.31 ? 102 ASN A C    1 
ATOM 1424 O O    . ASN A 1 102 ? 152.314 95.676  84.797  1.00 149.05 ? 102 ASN A O    1 
ATOM 1425 C CB   . ASN A 1 102 ? 155.280 96.203  86.208  1.00 142.13 ? 102 ASN A CB   1 
ATOM 1426 H H    . ASN A 1 102 ? 154.257 96.559  88.382  1.00 145.17 ? 102 ASN A H    1 
ATOM 1427 H HA   . ASN A 1 102 ? 153.629 97.397  85.997  1.00 148.59 ? 102 ASN A HA   1 
ATOM 1428 N N    . ALA A 1 103 ? 152.754 94.369  86.570  1.00 149.42 ? 103 ALA A N    1 
ATOM 1429 C CA   . ALA A 1 103 ? 151.940 93.275  86.060  1.00 147.54 ? 103 ALA A CA   1 
ATOM 1430 C C    . ALA A 1 103 ? 150.471 93.677  86.009  1.00 148.86 ? 103 ALA A C    1 
ATOM 1431 O O    . ALA A 1 103 ? 149.952 94.321  86.925  1.00 148.01 ? 103 ALA A O    1 
ATOM 1432 C CB   . ALA A 1 103 ? 152.114 92.033  86.932  1.00 144.19 ? 103 ALA A CB   1 
ATOM 1433 H H    . ALA A 1 103 ? 153.117 94.217  87.334  1.00 147.46 ? 103 ALA A H    1 
ATOM 1434 H HA   . ALA A 1 103 ? 152.226 93.057  85.159  1.00 146.93 ? 103 ALA A HA   1 
ATOM 1435 H HB1  . ALA A 1 103 ? 153.049 91.772  86.926  1.00 143.72 ? 103 ALA A HB1  1 
ATOM 1436 H HB2  . ALA A 1 103 ? 151.833 92.240  87.837  1.00 143.56 ? 103 ALA A HB2  1 
ATOM 1437 H HB3  . ALA A 1 103 ? 151.568 91.316  86.571  1.00 143.13 ? 103 ALA A HB3  1 
ATOM 1438 N N    . THR A 1 104 ? 149.801 93.289  84.927  1.00 152.69 ? 104 THR A N    1 
ATOM 1439 C CA   . THR A 1 104 ? 148.387 93.600  84.771  1.00 154.45 ? 104 THR A CA   1 
ATOM 1440 C C    . THR A 1 104 ? 147.559 92.840  85.799  1.00 152.28 ? 104 THR A C    1 
ATOM 1441 O O    . THR A 1 104 ? 147.826 91.673  86.099  1.00 147.89 ? 104 THR A O    1 
ATOM 1442 C CB   . THR A 1 104 ? 147.917 93.249  83.360  1.00 149.23 ? 104 THR A CB   1 
ATOM 1443 H H    . THR A 1 104 ? 150.142 92.848  84.273  1.00 150.82 ? 104 THR A H    1 
ATOM 1444 H HA   . THR A 1 104 ? 148.250 94.550  84.910  1.00 152.56 ? 104 THR A HA   1 
ATOM 1445 N N    . ALA A 1 105 ? 146.545 93.512  86.341  1.00 153.50 ? 105 ALA A N    1 
ATOM 1446 C CA   . ALA A 1 105 ? 145.678 92.917  87.350  1.00 150.86 ? 105 ALA A CA   1 
ATOM 1447 C C    . ALA A 1 105 ? 144.554 92.083  86.751  1.00 150.97 ? 105 ALA A C    1 
ATOM 1448 O O    . ALA A 1 105 ? 143.772 91.496  87.507  1.00 149.78 ? 105 ALA A O    1 
ATOM 1449 C CB   . ALA A 1 105 ? 145.085 94.011  88.241  1.00 148.72 ? 105 ALA A CB   1 
ATOM 1450 H H    . ALA A 1 105 ? 146.338 94.321  86.137  1.00 152.57 ? 105 ALA A H    1 
ATOM 1451 H HA   . ALA A 1 105 ? 146.211 92.333  87.913  1.00 150.43 ? 105 ALA A HA   1 
ATOM 1452 H HB1  . ALA A 1 105 ? 144.510 93.599  88.905  1.00 143.28 ? 105 ALA A HB1  1 
ATOM 1453 H HB2  . ALA A 1 105 ? 145.808 94.487  88.679  1.00 149.89 ? 105 ALA A HB2  1 
ATOM 1454 H HB3  . ALA A 1 105 ? 144.571 94.622  87.690  1.00 148.39 ? 105 ALA A HB3  1 
ATOM 1455 N N    . THR A 1 106 ? 144.450 92.015  85.421  1.00 152.25 ? 106 THR A N    1 
ATOM 1456 C CA   . THR A 1 106 ? 143.404 91.206  84.805  1.00 149.94 ? 106 THR A CA   1 
ATOM 1457 C C    . THR A 1 106 ? 143.568 89.734  85.160  1.00 149.28 ? 106 THR A C    1 
ATOM 1458 O O    . THR A 1 106 ? 142.583 89.040  85.438  1.00 144.04 ? 106 THR A O    1 
ATOM 1459 C CB   . THR A 1 106 ? 143.419 91.394  83.288  1.00 144.74 ? 106 THR A CB   1 
ATOM 1460 H H    . THR A 1 106 ? 144.964 92.421  84.864  1.00 151.16 ? 106 THR A H    1 
ATOM 1461 H HA   . THR A 1 106 ? 142.540 91.501  85.135  1.00 149.11 ? 106 THR A HA   1 
ATOM 1462 N N    . ASN A 1 107 ? 144.808 89.238  85.155  1.00 147.53 ? 107 ASN A N    1 
ATOM 1463 C CA   . ASN A 1 107 ? 145.046 87.846  85.519  1.00 142.78 ? 107 ASN A CA   1 
ATOM 1464 C C    . ASN A 1 107 ? 144.632 87.567  86.958  1.00 142.39 ? 107 ASN A C    1 
ATOM 1465 O O    . ASN A 1 107 ? 144.266 86.434  87.289  1.00 137.31 ? 107 ASN A O    1 
ATOM 1466 C CB   . ASN A 1 107 ? 146.519 87.495  85.314  1.00 132.24 ? 107 ASN A CB   1 
ATOM 1467 H H    . ASN A 1 107 ? 145.516 89.681  84.946  1.00 146.73 ? 107 ASN A H    1 
ATOM 1468 H HA   . ASN A 1 107 ? 144.518 87.274  84.940  1.00 142.88 ? 107 ASN A HA   1 
ATOM 1469 N N    . TRP A 1 108 ? 144.683 88.579  87.822  1.00 142.48 ? 108 TRP A N    1 
ATOM 1470 C CA   . TRP A 1 108 ? 144.270 88.438  89.214  1.00 134.92 ? 108 TRP A CA   1 
ATOM 1471 C C    . TRP A 1 108 ? 142.768 88.683  89.297  1.00 132.46 ? 108 TRP A C    1 
ATOM 1472 O O    . TRP A 1 108 ? 142.304 89.813  89.109  1.00 131.45 ? 108 TRP A O    1 
ATOM 1473 C CB   . TRP A 1 108 ? 145.037 89.411  90.105  1.00 128.40 ? 108 TRP A CB   1 
ATOM 1474 H H    . TRP A 1 108 ? 144.958 89.369  87.622  1.00 142.85 ? 108 TRP A H    1 
ATOM 1475 H HA   . TRP A 1 108 ? 144.452 87.535  89.518  1.00 134.07 ? 108 TRP A HA   1 
ATOM 1476 N N    . SER A 1 109 ? 142.009 87.626  89.578  1.00 122.60 ? 109 SER A N    1 
ATOM 1477 C CA   . SER A 1 109 ? 140.558 87.700  89.648  1.00 116.33 ? 109 SER A CA   1 
ATOM 1478 C C    . SER A 1 109 ? 140.071 86.763  90.744  1.00 116.37 ? 109 SER A C    1 
ATOM 1479 O O    . SER A 1 109 ? 140.863 86.093  91.416  1.00 109.95 ? 109 SER A O    1 
ATOM 1480 C CB   . SER A 1 109 ? 139.922 87.350  88.297  1.00 119.05 ? 109 SER A CB   1 
ATOM 1481 H H    . SER A 1 109 ? 142.321 86.840  89.736  1.00 122.36 ? 109 SER A H    1 
ATOM 1482 H HA   . SER A 1 109 ? 140.294 88.603  89.883  1.00 112.90 ? 109 SER A HA   1 
ATOM 1483 N N    . GLU A 1 110 ? 138.751 86.715  90.923  1.00 118.73 ? 110 GLU A N    1 
ATOM 1484 C CA   . GLU A 1 110 ? 138.126 85.883  91.941  1.00 116.08 ? 110 GLU A CA   1 
ATOM 1485 C C    . GLU A 1 110 ? 137.823 84.474  91.443  1.00 115.07 ? 110 GLU A C    1 
ATOM 1486 O O    . GLU A 1 110 ? 137.020 83.767  92.062  1.00 111.23 ? 110 GLU A O    1 
ATOM 1487 C CB   . GLU A 1 110 ? 136.841 86.547  92.442  1.00 102.95 ? 110 GLU A CB   1 
ATOM 1488 H H    . GLU A 1 110 ? 138.189 87.166  90.455  1.00 114.97 ? 110 GLU A H    1 
ATOM 1489 H HA   . GLU A 1 110 ? 138.732 85.806  92.695  1.00 111.09 ? 110 GLU A HA   1 
ATOM 1490 N N    . ALA A 1 111 ? 138.445 84.052  90.340  1.00 114.77 ? 111 ALA A N    1 
ATOM 1491 C CA   . ALA A 1 111 ? 138.211 82.705  89.832  1.00 106.22 ? 111 ALA A CA   1 
ATOM 1492 C C    . ALA A 1 111 ? 138.670 81.653  90.833  1.00 101.34 ? 111 ALA A C    1 
ATOM 1493 O O    . ALA A 1 111 ? 137.988 80.642  91.039  1.00 87.15  ? 111 ALA A O    1 
ATOM 1494 C CB   . ALA A 1 111 ? 138.923 82.520  88.492  1.00 109.18 ? 111 ALA A CB   1 
ATOM 1495 H H    . ALA A 1 111 ? 138.998 84.519  89.875  1.00 113.42 ? 111 ALA A H    1 
ATOM 1496 H HA   . ALA A 1 111 ? 137.260 82.584  89.685  1.00 105.71 ? 111 ALA A HA   1 
ATOM 1497 H HB1  . ALA A 1 111 ? 138.753 81.622  88.166  1.00 107.33 ? 111 ALA A HB1  1 
ATOM 1498 H HB2  . ALA A 1 111 ? 138.580 83.172  87.861  1.00 110.41 ? 111 ALA A HB2  1 
ATOM 1499 H HB3  . ALA A 1 111 ? 139.875 82.652  88.619  1.00 108.39 ? 111 ALA A HB3  1 
ATOM 1500 N N    . ALA A 1 112 ? 139.823 81.871  91.462  1.00 113.26 ? 112 ALA A N    1 
ATOM 1501 C CA   . ALA A 1 112 ? 140.389 80.949  92.441  1.00 117.31 ? 112 ALA A CA   1 
ATOM 1502 C C    . ALA A 1 112 ? 140.299 81.516  93.855  1.00 101.70 ? 112 ALA A C    1 
ATOM 1503 O O    . ALA A 1 112 ? 141.181 81.295  94.687  1.00 82.60  ? 112 ALA A O    1 
ATOM 1504 C CB   . ALA A 1 112 ? 141.838 80.621  92.093  1.00 114.01 ? 112 ALA A CB   1 
ATOM 1505 H H    . ALA A 1 112 ? 140.309 82.569  91.333  1.00 110.21 ? 112 ALA A H    1 
ATOM 1506 H HA   . ALA A 1 112 ? 139.886 80.120  92.423  1.00 111.37 ? 112 ALA A HA   1 
ATOM 1507 H HB1  . ALA A 1 112 ? 141.864 80.206  91.216  1.00 110.78 ? 112 ALA A HB1  1 
ATOM 1508 H HB2  . ALA A 1 112 ? 142.354 81.443  92.085  1.00 108.52 ? 112 ALA A HB2  1 
ATOM 1509 H HB3  . ALA A 1 112 ? 142.194 80.013  92.759  1.00 109.78 ? 112 ALA A HB3  1 
ATOM 1510 N N    . THR A 1 113 ? 139.230 82.255  94.141  1.00 94.17  ? 113 THR A N    1 
ATOM 1511 C CA   . THR A 1 113 ? 139.056 82.898  95.435  1.00 83.02  ? 113 THR A CA   1 
ATOM 1512 C C    . THR A 1 113 ? 138.234 81.998  96.358  1.00 81.96  ? 113 THR A C    1 
ATOM 1513 O O    . THR A 1 113 ? 137.940 80.843  96.039  1.00 81.96  ? 113 THR A O    1 
ATOM 1514 C CB   . THR A 1 113 ? 138.405 84.268  95.258  1.00 78.12  ? 113 THR A CB   1 
ATOM 1515 H H    . THR A 1 113 ? 138.582 82.398  93.594  1.00 97.94  ? 113 THR A H    1 
ATOM 1516 H HA   . THR A 1 113 ? 139.926 83.030  95.845  1.00 85.62  ? 113 THR A HA   1 
ATOM 1517 N N    . GLU A 1 114 ? 137.857 82.525  97.515  1.00 81.50  ? 114 GLU A N    1 
ATOM 1518 C CA   . GLU A 1 114 ? 137.112 81.795  98.527  1.00 77.75  ? 114 GLU A CA   1 
ATOM 1519 C C    . GLU A 1 114 ? 136.076 82.721  99.145  1.00 73.59  ? 114 GLU A C    1 
ATOM 1520 O O    . GLU A 1 114 ? 136.267 83.942  99.170  1.00 78.87  ? 114 GLU A O    1 
ATOM 1521 C CB   . GLU A 1 114 ? 138.067 81.237  99.595  1.00 78.47  ? 114 GLU A CB   1 
ATOM 1522 C CG   . GLU A 1 114 ? 137.596 81.330  101.037 1.00 82.18  ? 114 GLU A CG   1 
ATOM 1523 C CD   . GLU A 1 114 ? 138.672 80.924  102.020 1.00 89.67  ? 114 GLU A CD   1 
ATOM 1524 O OE1  . GLU A 1 114 ? 139.369 79.921  101.761 1.00 83.13  ? 114 GLU A OE1  1 
ATOM 1525 O OE2  . GLU A 1 114 ? 138.824 81.610  103.052 1.00 100.50 ? 114 GLU A OE2  1 
ATOM 1526 H H    . GLU A 1 114 ? 138.032 83.335  97.744  1.00 78.30  ? 114 GLU A H    1 
ATOM 1527 H HA   . GLU A 1 114 ? 136.662 81.050  98.102  1.00 80.85  ? 114 GLU A HA   1 
ATOM 1528 H HB2  . GLU A 1 114 ? 138.222 80.298  99.404  1.00 82.89  ? 114 GLU A HB2  1 
ATOM 1529 H HB3  . GLU A 1 114 ? 138.906 81.720  99.534  1.00 79.26  ? 114 GLU A HB3  1 
ATOM 1530 H HG2  . GLU A 1 114 ? 137.376 82.250  101.242 1.00 84.64  ? 114 GLU A HG2  1 
ATOM 1531 H HG3  . GLU A 1 114 ? 136.830 80.754  101.172 1.00 86.22  ? 114 GLU A HG3  1 
ATOM 1532 N N    . PRO A 1 115 ? 134.973 82.176  99.659  1.00 63.91  ? 115 PRO A N    1 
ATOM 1533 C CA   . PRO A 1 115 ? 133.960 83.028  100.293 1.00 60.63  ? 115 PRO A CA   1 
ATOM 1534 C C    . PRO A 1 115 ? 134.454 83.588  101.618 1.00 66.09  ? 115 PRO A C    1 
ATOM 1535 O O    . PRO A 1 115 ? 135.527 83.247  102.119 1.00 71.94  ? 115 PRO A O    1 
ATOM 1536 C CB   . PRO A 1 115 ? 132.759 82.095  100.492 1.00 60.46  ? 115 PRO A CB   1 
ATOM 1537 C CG   . PRO A 1 115 ? 133.063 80.866  99.701  1.00 73.41  ? 115 PRO A CG   1 
ATOM 1538 C CD   . PRO A 1 115 ? 134.546 80.766  99.626  1.00 67.72  ? 115 PRO A CD   1 
ATOM 1539 H HA   . PRO A 1 115 ? 133.707 83.754  99.703  1.00 65.98  ? 115 PRO A HA   1 
ATOM 1540 H HB2  . PRO A 1 115 ? 132.671 81.880  101.434 1.00 63.55  ? 115 PRO A HB2  1 
ATOM 1541 H HB3  . PRO A 1 115 ? 131.953 82.523  100.163 1.00 62.89  ? 115 PRO A HB3  1 
ATOM 1542 H HG2  . PRO A 1 115 ? 132.696 80.091  100.155 1.00 71.89  ? 115 PRO A HG2  1 
ATOM 1543 H HG3  . PRO A 1 115 ? 132.682 80.951  98.814  1.00 72.47  ? 115 PRO A HG3  1 
ATOM 1544 H HD2  . PRO A 1 115 ? 134.892 80.280  100.389 1.00 69.74  ? 115 PRO A HD2  1 
ATOM 1545 H HD3  . PRO A 1 115 ? 134.798 80.348  98.790  1.00 72.21  ? 115 PRO A HD3  1 
ATOM 1546 N N    . CYS A 1 116 ? 133.638 84.471  102.195 1.00 67.10  ? 116 CYS A N    1 
ATOM 1547 C CA   . CYS A 1 116 ? 133.991 85.159  103.437 1.00 67.85  ? 116 CYS A CA   1 
ATOM 1548 C C    . CYS A 1 116 ? 133.699 84.226  104.609 1.00 66.71  ? 116 CYS A C    1 
ATOM 1549 O O    . CYS A 1 116 ? 132.659 84.295  105.269 1.00 63.30  ? 116 CYS A O    1 
ATOM 1550 C CB   . CYS A 1 116 ? 133.232 86.474  103.555 1.00 63.06  ? 116 CYS A CB   1 
ATOM 1551 S SG   . CYS A 1 116 ? 133.914 87.827  102.560 1.00 69.97  ? 116 CYS A SG   1 
ATOM 1552 H H    . CYS A 1 116 ? 132.868 84.691  101.883 1.00 66.42  ? 116 CYS A H    1 
ATOM 1553 H HA   . CYS A 1 116 ? 134.942 85.347  103.436 1.00 67.29  ? 116 CYS A HA   1 
ATOM 1554 H HB2  . CYS A 1 116 ? 132.318 86.328  103.264 1.00 63.64  ? 116 CYS A HB2  1 
ATOM 1555 H HB3  . CYS A 1 116 ? 133.239 86.757  104.483 1.00 64.08  ? 116 CYS A HB3  1 
ATOM 1556 N N    . VAL A 1 117 ? 134.653 83.329  104.866 1.00 67.39  ? 117 VAL A N    1 
ATOM 1557 C CA   . VAL A 1 117 ? 134.491 82.352  105.938 1.00 68.19  ? 117 VAL A CA   1 
ATOM 1558 C C    . VAL A 1 117 ? 134.591 83.024  107.303 1.00 69.18  ? 117 VAL A C    1 
ATOM 1559 O O    . VAL A 1 117 ? 133.823 82.711  108.220 1.00 71.94  ? 117 VAL A O    1 
ATOM 1560 C CB   . VAL A 1 117 ? 135.531 81.226  105.781 1.00 66.31  ? 117 VAL A CB   1 
ATOM 1561 C CG1  . VAL A 1 117 ? 135.877 80.608  107.133 1.00 62.14  ? 117 VAL A CG1  1 
ATOM 1562 C CG2  . VAL A 1 117 ? 135.023 80.165  104.816 1.00 69.79  ? 117 VAL A CG2  1 
ATOM 1563 H H    . VAL A 1 117 ? 135.395 83.267  104.437 1.00 67.12  ? 117 VAL A H    1 
ATOM 1564 H HA   . VAL A 1 117 ? 133.610 81.954  105.867 1.00 68.24  ? 117 VAL A HA   1 
ATOM 1565 H HB   . VAL A 1 117 ? 136.345 81.601  105.409 1.00 65.99  ? 117 VAL A HB   1 
ATOM 1566 H HG11 . VAL A 1 117 ? 136.363 79.783  106.981 1.00 63.11  ? 117 VAL A HG11 1 
ATOM 1567 H HG12 . VAL A 1 117 ? 136.433 81.224  107.636 1.00 62.83  ? 117 VAL A HG12 1 
ATOM 1568 H HG13 . VAL A 1 117 ? 135.058 80.420  107.617 1.00 64.86  ? 117 VAL A HG13 1 
ATOM 1569 H HG21 . VAL A 1 117 ? 135.693 79.468  104.733 1.00 67.72  ? 117 VAL A HG21 1 
ATOM 1570 H HG22 . VAL A 1 117 ? 134.197 79.791  105.161 1.00 69.64  ? 117 VAL A HG22 1 
ATOM 1571 H HG23 . VAL A 1 117 ? 134.864 80.576  103.951 1.00 69.02  ? 117 VAL A HG23 1 
ATOM 1572 N N    . ASP A 1 118 ? 135.534 83.951  107.463 1.00 67.37  ? 118 ASP A N    1 
ATOM 1573 C CA   . ASP A 1 118 ? 135.852 84.525  108.764 1.00 60.57  ? 118 ASP A CA   1 
ATOM 1574 C C    . ASP A 1 118 ? 135.053 85.782  109.088 1.00 57.54  ? 118 ASP A C    1 
ATOM 1575 O O    . ASP A 1 118 ? 135.270 86.374  110.150 1.00 61.03  ? 118 ASP A O    1 
ATOM 1576 C CB   . ASP A 1 118 ? 137.349 84.843  108.841 1.00 59.65  ? 118 ASP A CB   1 
ATOM 1577 C CG   . ASP A 1 118 ? 138.187 83.629  109.193 1.00 59.67  ? 118 ASP A CG   1 
ATOM 1578 O OD1  . ASP A 1 118 ? 137.853 82.939  110.180 1.00 61.15  ? 118 ASP A OD1  1 
ATOM 1579 O OD2  . ASP A 1 118 ? 139.179 83.363  108.482 1.00 63.99  ? 118 ASP A OD2  1 
ATOM 1580 H H    . ASP A 1 118 ? 136.011 84.266  106.820 1.00 66.55  ? 118 ASP A H    1 
ATOM 1581 H HA   . ASP A 1 118 ? 135.654 83.868  109.450 1.00 62.80  ? 118 ASP A HA   1 
ATOM 1582 H HB2  . ASP A 1 118 ? 137.648 85.173  107.980 1.00 61.05  ? 118 ASP A HB2  1 
ATOM 1583 H HB3  . ASP A 1 118 ? 137.496 85.517  109.524 1.00 59.51  ? 118 ASP A HB3  1 
ATOM 1584 N N    . GLY A 1 119 ? 134.144 86.205  108.215 1.00 54.08  ? 119 GLY A N    1 
ATOM 1585 C CA   . GLY A 1 119 ? 133.323 87.374  108.468 1.00 55.74  ? 119 GLY A CA   1 
ATOM 1586 C C    . GLY A 1 119 ? 133.770 88.578  107.661 1.00 59.77  ? 119 GLY A C    1 
ATOM 1587 O O    . GLY A 1 119 ? 134.712 88.530  106.864 1.00 65.00  ? 119 GLY A O    1 
ATOM 1588 H H    . GLY A 1 119 ? 133.984 85.824  107.460 1.00 58.65  ? 119 GLY A H    1 
ATOM 1589 H HA2  . GLY A 1 119 ? 132.402 87.176  108.236 1.00 57.61  ? 119 GLY A HA2  1 
ATOM 1590 H HA3  . GLY A 1 119 ? 133.360 87.603  109.409 1.00 57.10  ? 119 GLY A HA3  1 
ATOM 1591 N N    . TRP A 1 120 ? 133.066 89.684  107.886 1.00 55.19  ? 120 TRP A N    1 
ATOM 1592 C CA   . TRP A 1 120 ? 133.280 90.923  107.156 1.00 53.59  ? 120 TRP A CA   1 
ATOM 1593 C C    . TRP A 1 120 ? 133.835 91.999  108.080 1.00 55.21  ? 120 TRP A C    1 
ATOM 1594 O O    . TRP A 1 120 ? 133.606 91.981  109.292 1.00 66.18  ? 120 TRP A O    1 
ATOM 1595 C CB   . TRP A 1 120 ? 131.977 91.423  106.524 1.00 53.52  ? 120 TRP A CB   1 
ATOM 1596 C CG   . TRP A 1 120 ? 131.516 90.620  105.348 1.00 57.33  ? 120 TRP A CG   1 
ATOM 1597 C CD1  . TRP A 1 120 ? 131.597 90.974  104.034 1.00 56.81  ? 120 TRP A CD1  1 
ATOM 1598 C CD2  . TRP A 1 120 ? 130.882 89.336  105.378 1.00 59.86  ? 120 TRP A CD2  1 
ATOM 1599 N NE1  . TRP A 1 120 ? 131.063 89.987  103.243 1.00 61.10  ? 120 TRP A NE1  1 
ATOM 1600 C CE2  . TRP A 1 120 ? 130.616 88.970  104.044 1.00 60.87  ? 120 TRP A CE2  1 
ATOM 1601 C CE3  . TRP A 1 120 ? 130.517 88.458  106.403 1.00 60.18  ? 120 TRP A CE3  1 
ATOM 1602 C CZ2  . TRP A 1 120 ? 130.003 87.766  103.708 1.00 67.33  ? 120 TRP A CZ2  1 
ATOM 1603 C CZ3  . TRP A 1 120 ? 129.910 87.262  106.067 1.00 62.96  ? 120 TRP A CZ3  1 
ATOM 1604 C CH2  . TRP A 1 120 ? 129.659 86.927  104.730 1.00 67.50  ? 120 TRP A CH2  1 
ATOM 1605 H H    . TRP A 1 120 ? 132.443 89.739  108.476 1.00 56.38  ? 120 TRP A H    1 
ATOM 1606 H HA   . TRP A 1 120 ? 133.923 90.772  106.445 1.00 55.79  ? 120 TRP A HA   1 
ATOM 1607 H HB2  . TRP A 1 120 ? 131.276 91.392  107.194 1.00 54.73  ? 120 TRP A HB2  1 
ATOM 1608 H HB3  . TRP A 1 120 ? 132.106 92.337  106.226 1.00 53.76  ? 120 TRP A HB3  1 
ATOM 1609 H HD1  . TRP A 1 120 ? 131.966 91.768  103.718 1.00 54.88  ? 120 TRP A HD1  1 
ATOM 1610 H HE1  . TRP A 1 120 ? 131.016 90.006  102.385 1.00 62.34  ? 120 TRP A HE1  1 
ATOM 1611 H HE3  . TRP A 1 120 ? 130.682 88.673  107.292 1.00 59.65  ? 120 TRP A HE3  1 
ATOM 1612 H HZ2  . TRP A 1 120 ? 129.836 87.540  102.821 1.00 67.05  ? 120 TRP A HZ2  1 
ATOM 1613 H HZ3  . TRP A 1 120 ? 129.664 86.670  106.740 1.00 62.79  ? 120 TRP A HZ3  1 
ATOM 1614 H HH2  . TRP A 1 120 ? 129.249 86.116  104.534 1.00 66.86  ? 120 TRP A HH2  1 
ATOM 1615 N N    . VAL A 1 121 ? 134.567 92.941  107.490 1.00 54.33  ? 121 VAL A N    1 
ATOM 1616 C CA   . VAL A 1 121 ? 135.088 94.112  108.187 1.00 49.91  ? 121 VAL A CA   1 
ATOM 1617 C C    . VAL A 1 121 ? 134.390 95.338  107.616 1.00 49.73  ? 121 VAL A C    1 
ATOM 1618 O O    . VAL A 1 121 ? 134.442 95.578  106.404 1.00 54.16  ? 121 VAL A O    1 
ATOM 1619 C CB   . VAL A 1 121 ? 136.615 94.225  108.037 1.00 47.93  ? 121 VAL A CB   1 
ATOM 1620 C CG1  . VAL A 1 121 ? 137.109 95.578  108.529 1.00 54.34  ? 121 VAL A CG1  1 
ATOM 1621 C CG2  . VAL A 1 121 ? 137.308 93.098  108.784 1.00 51.28  ? 121 VAL A CG2  1 
ATOM 1622 H H    . VAL A 1 121 ? 134.783 92.920  106.657 1.00 53.48  ? 121 VAL A H    1 
ATOM 1623 H HA   . VAL A 1 121 ? 134.876 94.049  109.132 1.00 51.14  ? 121 VAL A HA   1 
ATOM 1624 H HB   . VAL A 1 121 ? 136.846 94.147  107.098 1.00 50.81  ? 121 VAL A HB   1 
ATOM 1625 H HG11 . VAL A 1 121 ? 138.079 95.570  108.538 1.00 55.68  ? 121 VAL A HG11 1 
ATOM 1626 H HG12 . VAL A 1 121 ? 136.796 96.275  107.932 1.00 53.28  ? 121 VAL A HG12 1 
ATOM 1627 H HG13 . VAL A 1 121 ? 136.774 95.730  109.426 1.00 53.16  ? 121 VAL A HG13 1 
ATOM 1628 H HG21 . VAL A 1 121 ? 138.268 93.193  108.676 1.00 54.19  ? 121 VAL A HG21 1 
ATOM 1629 H HG22 . VAL A 1 121 ? 137.075 93.151  109.724 1.00 54.78  ? 121 VAL A HG22 1 
ATOM 1630 H HG23 . VAL A 1 121 ? 137.016 92.249  108.417 1.00 53.66  ? 121 VAL A HG23 1 
ATOM 1631 N N    . TYR A 1 122 ? 133.749 96.114  108.483 1.00 52.27  ? 122 TYR A N    1 
ATOM 1632 C CA   . TYR A 1 122 ? 132.932 97.246  108.071 1.00 51.92  ? 122 TYR A CA   1 
ATOM 1633 C C    . TYR A 1 122 ? 133.655 98.554  108.375 1.00 58.45  ? 122 TYR A C    1 
ATOM 1634 O O    . TYR A 1 122 ? 134.787 98.573  108.869 1.00 66.33  ? 122 TYR A O    1 
ATOM 1635 C CB   . TYR A 1 122 ? 131.564 97.208  108.759 1.00 53.10  ? 122 TYR A CB   1 
ATOM 1636 C CG   . TYR A 1 122 ? 130.786 95.931  108.534 1.00 53.67  ? 122 TYR A CG   1 
ATOM 1637 C CD1  . TYR A 1 122 ? 131.235 94.718  109.038 1.00 55.05  ? 122 TYR A CD1  1 
ATOM 1638 C CD2  . TYR A 1 122 ? 129.607 95.936  107.803 1.00 50.96  ? 122 TYR A CD2  1 
ATOM 1639 C CE1  . TYR A 1 122 ? 130.527 93.552  108.831 1.00 54.60  ? 122 TYR A CE1  1 
ATOM 1640 C CE2  . TYR A 1 122 ? 128.894 94.774  107.588 1.00 45.08  ? 122 TYR A CE2  1 
ATOM 1641 C CZ   . TYR A 1 122 ? 129.359 93.585  108.105 1.00 52.06  ? 122 TYR A CZ   1 
ATOM 1642 O OH   . TYR A 1 122 ? 128.653 92.423  107.896 1.00 61.16  ? 122 TYR A OH   1 
ATOM 1643 H H    . TYR A 1 122 ? 133.775 96.002  109.335 1.00 54.10  ? 122 TYR A H    1 
ATOM 1644 H HA   . TYR A 1 122 ? 132.786 97.201  107.114 1.00 51.20  ? 122 TYR A HA   1 
ATOM 1645 H HB2  . TYR A 1 122 ? 131.695 97.308  109.715 1.00 54.07  ? 122 TYR A HB2  1 
ATOM 1646 H HB3  . TYR A 1 122 ? 131.027 97.942  108.424 1.00 51.98  ? 122 TYR A HB3  1 
ATOM 1647 H HD1  . TYR A 1 122 ? 132.024 94.692  109.530 1.00 54.39  ? 122 TYR A HD1  1 
ATOM 1648 H HD2  . TYR A 1 122 ? 129.290 96.738  107.454 1.00 50.93  ? 122 TYR A HD2  1 
ATOM 1649 H HE1  . TYR A 1 122 ? 130.840 92.747  109.177 1.00 54.06  ? 122 TYR A HE1  1 
ATOM 1650 H HE2  . TYR A 1 122 ? 128.103 94.794  107.099 1.00 46.40  ? 122 TYR A HE2  1 
ATOM 1651 H HH   . TYR A 1 122 ? 127.968 92.582  107.437 1.00 58.25  ? 122 TYR A HH   1 
ATOM 1652 N N    . ASP A 1 123 ? 132.982 99.661  108.074 1.00 61.60  ? 123 ASP A N    1 
ATOM 1653 C CA   . ASP A 1 123 ? 133.533 100.999 108.238 1.00 68.36  ? 123 ASP A CA   1 
ATOM 1654 C C    . ASP A 1 123 ? 132.784 101.727 109.345 1.00 63.72  ? 123 ASP A C    1 
ATOM 1655 O O    . ASP A 1 123 ? 131.549 101.763 109.345 1.00 60.88  ? 123 ASP A O    1 
ATOM 1656 C CB   . ASP A 1 123 ? 133.441 101.789 106.931 1.00 65.68  ? 123 ASP A CB   1 
ATOM 1657 C CG   . ASP A 1 123 ? 134.431 102.933 106.869 1.00 67.90  ? 123 ASP A CG   1 
ATOM 1658 O OD1  . ASP A 1 123 ? 135.651 102.665 106.856 1.00 69.47  ? 123 ASP A OD1  1 
ATOM 1659 O OD2  . ASP A 1 123 ? 133.990 104.101 106.832 1.00 67.83  ? 123 ASP A OD2  1 
ATOM 1660 H H    . ASP A 1 123 ? 132.179 99.660  107.765 1.00 58.63  ? 123 ASP A H    1 
ATOM 1661 H HA   . ASP A 1 123 ? 134.467 100.937 108.491 1.00 65.69  ? 123 ASP A HA   1 
ATOM 1662 H HB2  . ASP A 1 123 ? 133.624 101.193 106.187 1.00 61.90  ? 123 ASP A HB2  1 
ATOM 1663 H HB3  . ASP A 1 123 ? 132.548 102.160 106.848 1.00 61.79  ? 123 ASP A HB3  1 
ATOM 1664 N N    . ARG A 1 124 ? 133.534 102.307 110.282 1.00 62.56  ? 124 ARG A N    1 
ATOM 1665 C CA   . ARG A 1 124 ? 132.971 103.028 111.415 1.00 64.12  ? 124 ARG A CA   1 
ATOM 1666 C C    . ARG A 1 124 ? 133.198 104.534 111.312 1.00 67.74  ? 124 ARG A C    1 
ATOM 1667 O O    . ARG A 1 124 ? 133.044 105.250 112.306 1.00 72.25  ? 124 ARG A O    1 
ATOM 1668 C CB   . ARG A 1 124 ? 133.560 102.500 112.725 1.00 64.33  ? 124 ARG A CB   1 
ATOM 1669 C CG   . ARG A 1 124 ? 133.735 100.987 112.790 1.00 60.67  ? 124 ARG A CG   1 
ATOM 1670 C CD   . ARG A 1 124 ? 132.397 100.270 112.859 1.00 58.80  ? 124 ARG A CD   1 
ATOM 1671 N NE   . ARG A 1 124 ? 132.551 98.820  112.855 1.00 63.97  ? 124 ARG A NE   1 
ATOM 1672 C CZ   . ARG A 1 124 ? 131.562 97.959  112.659 1.00 66.03  ? 124 ARG A CZ   1 
ATOM 1673 N NH1  . ARG A 1 124 ? 130.319 98.367  112.462 1.00 63.31  ? 124 ARG A NH1  1 
ATOM 1674 N NH2  . ARG A 1 124 ? 131.825 96.656  112.662 1.00 61.98  ? 124 ARG A NH2  1 
ATOM 1675 H H    . ARG A 1 124 ? 134.394 102.295 110.279 1.00 63.47  ? 124 ARG A H    1 
ATOM 1676 H HA   . ARG A 1 124 ? 132.014 102.875 111.440 1.00 63.20  ? 124 ARG A HA   1 
ATOM 1677 H HB2  . ARG A 1 124 ? 134.434 102.900 112.854 1.00 64.78  ? 124 ARG A HB2  1 
ATOM 1678 H HB3  . ARG A 1 124 ? 132.974 102.758 113.454 1.00 64.22  ? 124 ARG A HB3  1 
ATOM 1679 H HG2  . ARG A 1 124 ? 134.209 100.676 112.004 1.00 61.85  ? 124 ARG A HG2  1 
ATOM 1680 H HG3  . ARG A 1 124 ? 134.237 100.762 113.589 1.00 61.82  ? 124 ARG A HG3  1 
ATOM 1681 H HD2  . ARG A 1 124 ? 131.943 100.523 113.678 1.00 60.17  ? 124 ARG A HD2  1 
ATOM 1682 H HD3  . ARG A 1 124 ? 131.863 100.520 112.089 1.00 60.54  ? 124 ARG A HD3  1 
ATOM 1683 H HE   . ARG A 1 124 ? 133.334 98.500  113.015 1.00 63.76  ? 124 ARG A HE   1 
ATOM 1684 H HH11 . ARG A 1 124 ? 130.135 99.207  112.458 1.00 61.28  ? 124 ARG A HH11 1 
ATOM 1685 H HH12 . ARG A 1 124 ? 129.694 97.791  112.338 1.00 62.11  ? 124 ARG A HH12 1 
ATOM 1686 H HH21 . ARG A 1 124 ? 132.630 96.380  112.789 1.00 59.82  ? 124 ARG A HH21 1 
ATOM 1687 H HH22 . ARG A 1 124 ? 131.192 96.088  112.537 1.00 60.74  ? 124 ARG A HH22 1 
ATOM 1688 N N    . SER A 1 125 ? 133.566 105.029 110.128 1.00 68.38  ? 125 SER A N    1 
ATOM 1689 C CA   . SER A 1 125 ? 133.875 106.449 109.984 1.00 63.63  ? 125 SER A CA   1 
ATOM 1690 C C    . SER A 1 125 ? 132.628 107.310 110.149 1.00 56.63  ? 125 SER A C    1 
ATOM 1691 O O    . SER A 1 125 ? 132.652 108.323 110.857 1.00 55.75  ? 125 SER A O    1 
ATOM 1692 C CB   . SER A 1 125 ? 134.531 106.704 108.626 1.00 70.17  ? 125 SER A CB   1 
ATOM 1693 O OG   . SER A 1 125 ? 133.596 107.212 107.692 1.00 71.27  ? 125 SER A OG   1 
ATOM 1694 H H    . SER A 1 125 ? 133.643 104.571 109.405 1.00 67.59  ? 125 SER A H    1 
ATOM 1695 H HA   . SER A 1 125 ? 134.507 106.705 110.674 1.00 63.86  ? 125 SER A HA   1 
ATOM 1696 H HB2  . SER A 1 125 ? 135.241 107.355 108.742 1.00 68.22  ? 125 SER A HB2  1 
ATOM 1697 H HB3  . SER A 1 125 ? 134.898 105.872 108.289 1.00 69.64  ? 125 SER A HB3  1 
ATOM 1698 H HG   . SER A 1 125 ? 133.976 107.363 106.958 1.00 69.79  ? 125 SER A HG   1 
ATOM 1699 N N    . THR A 1 126 ? 131.526 106.924 109.505 1.00 52.70  ? 126 THR A N    1 
ATOM 1700 C CA   . THR A 1 126 ? 130.295 107.710 109.529 1.00 58.18  ? 126 THR A CA   1 
ATOM 1701 C C    . THR A 1 126 ? 129.282 107.179 110.539 1.00 60.14  ? 126 THR A C    1 
ATOM 1702 O O    . THR A 1 126 ? 128.736 107.954 111.329 1.00 61.10  ? 126 THR A O    1 
ATOM 1703 C CB   . THR A 1 126 ? 129.660 107.768 108.129 1.00 66.36  ? 126 THR A CB   1 
ATOM 1704 O OG1  . THR A 1 126 ? 128.310 108.236 108.234 1.00 70.51  ? 126 THR A OG1  1 
ATOM 1705 C CG2  . THR A 1 126 ? 129.666 106.404 107.441 1.00 61.62  ? 126 THR A CG2  1 
ATOM 1706 H H    . THR A 1 126 ? 131.469 106.194 109.058 1.00 58.96  ? 126 THR A H    1 
ATOM 1707 H HA   . THR A 1 126 ? 130.513 108.619 109.787 1.00 59.42  ? 126 THR A HA   1 
ATOM 1708 H HB   . THR A 1 126 ? 130.168 108.385 107.579 1.00 66.02  ? 126 THR A HB   1 
ATOM 1709 H HG1  . THR A 1 126 ? 127.959 108.272 107.471 1.00 68.30  ? 126 THR A HG1  1 
ATOM 1710 H HG21 . THR A 1 126 ? 129.221 106.473 106.582 1.00 62.37  ? 126 THR A HG21 1 
ATOM 1711 H HG22 . THR A 1 126 ? 130.575 106.103 107.293 1.00 62.42  ? 126 THR A HG22 1 
ATOM 1712 H HG23 . THR A 1 126 ? 129.196 105.751 107.982 1.00 62.28  ? 126 THR A HG23 1 
ATOM 1713 N N    . PHE A 1 127 ? 129.017 105.876 110.530 1.00 60.10  ? 127 PHE A N    1 
ATOM 1714 C CA   . PHE A 1 127 ? 128.140 105.237 111.502 1.00 55.65  ? 127 PHE A CA   1 
ATOM 1715 C C    . PHE A 1 127 ? 128.978 104.376 112.436 1.00 63.22  ? 127 PHE A C    1 
ATOM 1716 O O    . PHE A 1 127 ? 129.763 103.541 111.975 1.00 66.06  ? 127 PHE A O    1 
ATOM 1717 C CB   . PHE A 1 127 ? 127.082 104.376 110.808 1.00 51.01  ? 127 PHE A CB   1 
ATOM 1718 C CG   . PHE A 1 127 ? 125.889 105.147 110.318 1.00 50.56  ? 127 PHE A CG   1 
ATOM 1719 C CD1  . PHE A 1 127 ? 125.076 105.832 111.204 1.00 54.48  ? 127 PHE A CD1  1 
ATOM 1720 C CD2  . PHE A 1 127 ? 125.579 105.181 108.969 1.00 51.75  ? 127 PHE A CD2  1 
ATOM 1721 C CE1  . PHE A 1 127 ? 123.978 106.539 110.752 1.00 57.34  ? 127 PHE A CE1  1 
ATOM 1722 C CE2  . PHE A 1 127 ? 124.483 105.885 108.513 1.00 56.53  ? 127 PHE A CE2  1 
ATOM 1723 C CZ   . PHE A 1 127 ? 123.682 106.564 109.404 1.00 59.09  ? 127 PHE A CZ   1 
ATOM 1724 H H    . PHE A 1 127 ? 129.347 105.327 109.956 1.00 60.18  ? 127 PHE A H    1 
ATOM 1725 H HA   . PHE A 1 127 ? 127.691 105.913 112.033 1.00 56.89  ? 127 PHE A HA   1 
ATOM 1726 H HB2  . PHE A 1 127 ? 127.488 103.940 110.042 1.00 54.48  ? 127 PHE A HB2  1 
ATOM 1727 H HB3  . PHE A 1 127 ? 126.764 103.708 111.435 1.00 54.00  ? 127 PHE A HB3  1 
ATOM 1728 H HD1  . PHE A 1 127 ? 125.271 105.818 112.113 1.00 55.41  ? 127 PHE A HD1  1 
ATOM 1729 H HD2  . PHE A 1 127 ? 126.116 104.724 108.363 1.00 53.98  ? 127 PHE A HD2  1 
ATOM 1730 H HE1  . PHE A 1 127 ? 123.438 106.997 111.355 1.00 56.64  ? 127 PHE A HE1  1 
ATOM 1731 H HE2  . PHE A 1 127 ? 124.286 105.901 107.605 1.00 55.82  ? 127 PHE A HE2  1 
ATOM 1732 H HZ   . PHE A 1 127 ? 122.944 107.039 109.098 1.00 57.17  ? 127 PHE A HZ   1 
ATOM 1733 N N    . THR A 1 128 ? 128.811 104.575 113.746 1.00 59.60  ? 128 THR A N    1 
ATOM 1734 C CA   . THR A 1 128 ? 129.551 103.759 114.704 1.00 58.92  ? 128 THR A CA   1 
ATOM 1735 C C    . THR A 1 128 ? 129.046 102.322 114.707 1.00 60.67  ? 128 THR A C    1 
ATOM 1736 O O    . THR A 1 128 ? 129.837 101.381 114.843 1.00 67.80  ? 128 THR A O    1 
ATOM 1737 C CB   . THR A 1 128 ? 129.468 104.353 116.115 1.00 62.95  ? 128 THR A CB   1 
ATOM 1738 O OG1  . THR A 1 128 ? 128.281 103.886 116.771 1.00 71.95  ? 128 THR A OG1  1 
ATOM 1739 C CG2  . THR A 1 128 ? 129.493 105.878 116.095 1.00 61.57  ? 128 THR A CG2  1 
ATOM 1740 H H    . THR A 1 128 ? 128.276 105.152 114.089 1.00 59.88  ? 128 THR A H    1 
ATOM 1741 H HA   . THR A 1 128 ? 130.486 103.743 114.445 1.00 61.51  ? 128 THR A HA   1 
ATOM 1742 H HB   . THR A 1 128 ? 130.239 104.054 116.622 1.00 63.96  ? 128 THR A HB   1 
ATOM 1743 H HG1  . THR A 1 128 ? 128.207 104.249 117.524 1.00 69.89  ? 128 THR A HG1  1 
ATOM 1744 H HG21 . THR A 1 128 ? 129.562 106.218 117.002 1.00 61.48  ? 128 THR A HG21 1 
ATOM 1745 H HG22 . THR A 1 128 ? 130.256 106.192 115.585 1.00 64.61  ? 128 THR A HG22 1 
ATOM 1746 H HG23 . THR A 1 128 ? 128.682 106.222 115.697 1.00 61.38  ? 128 THR A HG23 1 
ATOM 1747 N N    . SER A 1 129 ? 127.737 102.131 114.564 1.00 56.34  ? 129 SER A N    1 
ATOM 1748 C CA   . SER A 1 129 ? 127.164 100.794 114.527 1.00 58.60  ? 129 SER A CA   1 
ATOM 1749 C C    . SER A 1 129 ? 125.891 100.822 113.697 1.00 53.92  ? 129 SER A C    1 
ATOM 1750 O O    . SER A 1 129 ? 125.251 101.864 113.538 1.00 56.81  ? 129 SER A O    1 
ATOM 1751 C CB   . SER A 1 129 ? 126.872 100.267 115.936 1.00 59.11  ? 129 SER A CB   1 
ATOM 1752 O OG   . SER A 1 129 ? 126.535 98.891  115.903 1.00 58.58  ? 129 SER A OG   1 
ATOM 1753 H H    . SER A 1 129 ? 127.159 102.763 114.488 1.00 57.82  ? 129 SER A H    1 
ATOM 1754 H HA   . SER A 1 129 ? 127.791 100.189 114.100 1.00 59.57  ? 129 SER A HA   1 
ATOM 1755 H HB2  . SER A 1 129 ? 127.662 100.386 116.486 1.00 58.88  ? 129 SER A HB2  1 
ATOM 1756 H HB3  . SER A 1 129 ? 126.129 100.765 116.310 1.00 59.12  ? 129 SER A HB3  1 
ATOM 1757 H HG   . SER A 1 129 ? 126.377 98.616  116.680 1.00 59.38  ? 129 SER A HG   1 
ATOM 1758 N N    . THR A 1 130 ? 125.528 99.656  113.171 1.00 52.09  ? 130 THR A N    1 
ATOM 1759 C CA   . THR A 1 130 ? 124.331 99.526  112.353 1.00 53.90  ? 130 THR A CA   1 
ATOM 1760 C C    . THR A 1 130 ? 123.841 98.089  112.436 1.00 57.66  ? 130 THR A C    1 
ATOM 1761 O O    . THR A 1 130 ? 124.595 97.174  112.775 1.00 59.94  ? 130 THR A O    1 
ATOM 1762 C CB   . THR A 1 130 ? 124.596 99.917  110.895 1.00 54.13  ? 130 THR A CB   1 
ATOM 1763 O OG1  . THR A 1 130 ? 125.535 100.998 110.846 1.00 56.70  ? 130 THR A OG1  1 
ATOM 1764 C CG2  . THR A 1 130 ? 123.310 100.344 110.214 1.00 55.43  ? 130 THR A CG2  1 
ATOM 1765 H H    . THR A 1 130 ? 125.964 98.921  113.273 1.00 55.75  ? 130 THR A H    1 
ATOM 1766 H HA   . THR A 1 130 ? 123.638 100.106 112.705 1.00 54.34  ? 130 THR A HA   1 
ATOM 1767 H HB   . THR A 1 130 ? 124.958 99.154  110.417 1.00 55.06  ? 130 THR A HB   1 
ATOM 1768 H HG1  . THR A 1 130 ? 125.703 101.196 110.047 1.00 55.05  ? 130 THR A HG1  1 
ATOM 1769 H HG21 . THR A 1 130 ? 123.507 100.692 109.331 1.00 55.35  ? 130 THR A HG21 1 
ATOM 1770 H HG22 . THR A 1 130 ? 122.712 99.585  110.127 1.00 56.75  ? 130 THR A HG22 1 
ATOM 1771 H HG23 . THR A 1 130 ? 122.872 101.035 110.734 1.00 55.87  ? 130 THR A HG23 1 
ATOM 1772 N N    . ILE A 1 131 ? 122.559 97.906  112.117 1.00 54.09  ? 131 ILE A N    1 
ATOM 1773 C CA   . ILE A 1 131 ? 121.963 96.573  112.160 1.00 49.29  ? 131 ILE A CA   1 
ATOM 1774 C C    . ILE A 1 131 ? 122.622 95.661  111.134 1.00 50.05  ? 131 ILE A C    1 
ATOM 1775 O O    . ILE A 1 131 ? 122.839 94.467  111.385 1.00 51.64  ? 131 ILE A O    1 
ATOM 1776 C CB   . ILE A 1 131 ? 120.441 96.670  111.947 1.00 46.54  ? 131 ILE A CB   1 
ATOM 1777 C CG1  . ILE A 1 131 ? 119.760 95.396  112.438 1.00 50.98  ? 131 ILE A CG1  1 
ATOM 1778 C CG2  . ILE A 1 131 ? 120.118 96.922  110.485 1.00 48.92  ? 131 ILE A CG2  1 
ATOM 1779 C CD1  . ILE A 1 131 ? 118.317 95.268  112.014 1.00 53.05  ? 131 ILE A CD1  1 
ATOM 1780 H H    . ILE A 1 131 ? 122.019 98.530  111.875 1.00 54.45  ? 131 ILE A H    1 
ATOM 1781 H HA   . ILE A 1 131 ? 122.116 96.190  113.038 1.00 51.17  ? 131 ILE A HA   1 
ATOM 1782 H HB   . ILE A 1 131 ? 120.106 97.417  112.468 1.00 49.98  ? 131 ILE A HB   1 
ATOM 1783 H HG12 . ILE A 1 131 ? 120.242 94.636  112.078 1.00 51.00  ? 131 ILE A HG12 1 
ATOM 1784 H HG13 . ILE A 1 131 ? 119.791 95.379  113.407 1.00 52.16  ? 131 ILE A HG13 1 
ATOM 1785 H HG21 . ILE A 1 131 ? 119.219 97.280  110.416 1.00 51.05  ? 131 ILE A HG21 1 
ATOM 1786 H HG22 . ILE A 1 131 ? 120.754 97.561  110.128 1.00 52.15  ? 131 ILE A HG22 1 
ATOM 1787 H HG23 . ILE A 1 131 ? 120.181 96.086  109.997 1.00 50.09  ? 131 ILE A HG23 1 
ATOM 1788 H HD11 . ILE A 1 131 ? 117.910 94.536  112.505 1.00 53.89  ? 131 ILE A HD11 1 
ATOM 1789 H HD12 . ILE A 1 131 ? 117.855 96.097  112.213 1.00 51.85  ? 131 ILE A HD12 1 
ATOM 1790 H HD13 . ILE A 1 131 ? 118.278 95.087  111.062 1.00 52.02  ? 131 ILE A HD13 1 
ATOM 1791 N N    . VAL A 1 132 ? 122.953 96.207  109.962 1.00 54.37  ? 132 VAL A N    1 
ATOM 1792 C CA   . VAL A 1 132 ? 123.597 95.411  108.923 1.00 53.49  ? 132 VAL A CA   1 
ATOM 1793 C C    . VAL A 1 132 ? 124.940 94.892  109.412 1.00 49.61  ? 132 VAL A C    1 
ATOM 1794 O O    . VAL A 1 132 ? 125.284 93.722  109.206 1.00 50.78  ? 132 VAL A O    1 
ATOM 1795 C CB   . VAL A 1 132 ? 123.746 96.244  107.636 1.00 50.71  ? 132 VAL A CB   1 
ATOM 1796 C CG1  . VAL A 1 132 ? 124.606 95.510  106.617 1.00 49.30  ? 132 VAL A CG1  1 
ATOM 1797 C CG2  . VAL A 1 132 ? 122.380 96.573  107.056 1.00 54.78  ? 132 VAL A CG2  1 
ATOM 1798 H H    . VAL A 1 132 ? 122.818 97.029  109.749 1.00 54.00  ? 132 VAL A H    1 
ATOM 1799 H HA   . VAL A 1 132 ? 123.037 94.646  108.720 1.00 53.40  ? 132 VAL A HA   1 
ATOM 1800 H HB   . VAL A 1 132 ? 124.189 97.080  107.852 1.00 52.02  ? 132 VAL A HB   1 
ATOM 1801 H HG11 . VAL A 1 132 ? 125.535 95.555  106.893 1.00 50.37  ? 132 VAL A HG11 1 
ATOM 1802 H HG12 . VAL A 1 132 ? 124.319 94.585  106.568 1.00 51.39  ? 132 VAL A HG12 1 
ATOM 1803 H HG13 . VAL A 1 132 ? 124.503 95.936  105.752 1.00 50.61  ? 132 VAL A HG13 1 
ATOM 1804 H HG21 . VAL A 1 132 ? 121.694 96.234  107.652 1.00 54.84  ? 132 VAL A HG21 1 
ATOM 1805 H HG22 . VAL A 1 132 ? 122.298 97.536  106.972 1.00 54.59  ? 132 VAL A HG22 1 
ATOM 1806 H HG23 . VAL A 1 132 ? 122.296 96.157  106.184 1.00 53.92  ? 132 VAL A HG23 1 
ATOM 1807 N N    . ALA A 1 133 ? 125.721 95.750  110.068 1.00 49.88  ? 133 ALA A N    1 
ATOM 1808 C CA   . ALA A 1 133 ? 127.020 95.328  110.574 1.00 56.28  ? 133 ALA A CA   1 
ATOM 1809 C C    . ALA A 1 133 ? 126.897 94.416  111.783 1.00 58.63  ? 133 ALA A C    1 
ATOM 1810 O O    . ALA A 1 133 ? 127.851 93.697  112.100 1.00 61.18  ? 133 ALA A O    1 
ATOM 1811 C CB   . ALA A 1 133 ? 127.866 96.550  110.932 1.00 58.23  ? 133 ALA A CB   1 
ATOM 1812 H H    . ALA A 1 133 ? 125.524 96.571  110.230 1.00 52.32  ? 133 ALA A H    1 
ATOM 1813 H HA   . ALA A 1 133 ? 127.482 94.836  109.880 1.00 54.05  ? 133 ALA A HA   1 
ATOM 1814 H HB1  . ALA A 1 133 ? 128.729 96.249  111.257 1.00 56.34  ? 133 ALA A HB1  1 
ATOM 1815 H HB2  . ALA A 1 133 ? 127.984 97.096  110.138 1.00 56.76  ? 133 ALA A HB2  1 
ATOM 1816 H HB3  . ALA A 1 133 ? 127.411 97.059  111.620 1.00 57.30  ? 133 ALA A HB3  1 
ATOM 1817 N N    . LYS A 1 134 ? 125.749 94.417  112.457 1.00 52.21  ? 134 LYS A N    1 
ATOM 1818 C CA   . LYS A 1 134 ? 125.576 93.586  113.640 1.00 52.73  ? 134 LYS A CA   1 
ATOM 1819 C C    . LYS A 1 134 ? 125.115 92.177  113.292 1.00 51.70  ? 134 LYS A C    1 
ATOM 1820 O O    . LYS A 1 134 ? 125.560 91.213  113.923 1.00 49.18  ? 134 LYS A O    1 
ATOM 1821 C CB   . LYS A 1 134 ? 124.575 94.231  114.600 1.00 55.68  ? 134 LYS A CB   1 
ATOM 1822 C CG   . LYS A 1 134 ? 124.683 93.712  116.024 1.00 59.59  ? 134 LYS A CG   1 
ATOM 1823 C CD   . LYS A 1 134 ? 123.430 94.001  116.832 1.00 56.16  ? 134 LYS A CD   1 
ATOM 1824 C CE   . LYS A 1 134 ? 122.733 92.719  117.258 1.00 52.74  ? 134 LYS A CE   1 
ATOM 1825 N NZ   . LYS A 1 134 ? 123.360 92.119  118.468 1.00 57.68  ? 134 LYS A NZ   1 
ATOM 1826 H H    . LYS A 1 134 ? 125.060 94.888  112.251 1.00 53.00  ? 134 LYS A H    1 
ATOM 1827 H HA   . LYS A 1 134 ? 126.426 93.515  114.101 1.00 54.03  ? 134 LYS A HA   1 
ATOM 1828 H HB2  . LYS A 1 134 ? 124.731 95.188  114.619 1.00 54.07  ? 134 LYS A HB2  1 
ATOM 1829 H HB3  . LYS A 1 134 ? 123.677 94.049  114.282 1.00 55.30  ? 134 LYS A HB3  1 
ATOM 1830 H HG2  . LYS A 1 134 ? 124.822 92.752  116.005 1.00 57.07  ? 134 LYS A HG2  1 
ATOM 1831 H HG3  . LYS A 1 134 ? 125.431 94.147  116.464 1.00 57.77  ? 134 LYS A HG3  1 
ATOM 1832 H HD2  . LYS A 1 134 ? 123.673 94.494  117.631 1.00 55.66  ? 134 LYS A HD2  1 
ATOM 1833 H HD3  . LYS A 1 134 ? 122.812 94.519  116.294 1.00 56.52  ? 134 LYS A HD3  1 
ATOM 1834 H HE2  . LYS A 1 134 ? 121.806 92.915  117.465 1.00 52.91  ? 134 LYS A HE2  1 
ATOM 1835 H HE3  . LYS A 1 134 ? 122.785 92.071  116.538 1.00 54.04  ? 134 LYS A HE3  1 
ATOM 1836 H HZ1  . LYS A 1 134 ? 122.932 91.372  118.693 1.00 57.98  ? 134 LYS A HZ1  1 
ATOM 1837 H HZ2  . LYS A 1 134 ? 124.213 91.926  118.304 1.00 56.92  ? 134 LYS A HZ2  1 
ATOM 1838 H HZ3  . LYS A 1 134 ? 123.319 92.692  119.148 1.00 57.99  ? 134 LYS A HZ3  1 
ATOM 1839 N N    . TRP A 1 135 ? 124.231 92.032  112.302 1.00 49.98  ? 135 TRP A N    1 
ATOM 1840 C CA   . TRP A 1 135 ? 123.717 90.721  111.924 1.00 50.01  ? 135 TRP A CA   1 
ATOM 1841 C C    . TRP A 1 135 ? 124.159 90.296  110.526 1.00 55.20  ? 135 TRP A C    1 
ATOM 1842 O O    . TRP A 1 135 ? 123.548 89.401  109.934 1.00 61.95  ? 135 TRP A O    1 
ATOM 1843 C CB   . TRP A 1 135 ? 122.193 90.696  112.032 1.00 52.49  ? 135 TRP A CB   1 
ATOM 1844 C CG   . TRP A 1 135 ? 121.711 90.523  113.441 1.00 52.85  ? 135 TRP A CG   1 
ATOM 1845 C CD1  . TRP A 1 135 ? 122.099 89.560  114.327 1.00 52.71  ? 135 TRP A CD1  1 
ATOM 1846 C CD2  . TRP A 1 135 ? 120.741 91.326  114.123 1.00 49.03  ? 135 TRP A CD2  1 
ATOM 1847 N NE1  . TRP A 1 135 ? 121.439 89.720  115.520 1.00 55.20  ? 135 TRP A NE1  1 
ATOM 1848 C CE2  . TRP A 1 135 ? 120.597 90.796  115.420 1.00 50.55  ? 135 TRP A CE2  1 
ATOM 1849 C CE3  . TRP A 1 135 ? 119.982 92.442  113.764 1.00 46.84  ? 135 TRP A CE3  1 
ATOM 1850 C CZ2  . TRP A 1 135 ? 119.727 91.344  116.357 1.00 44.95  ? 135 TRP A CZ2  1 
ATOM 1851 C CZ3  . TRP A 1 135 ? 119.119 92.985  114.696 1.00 45.86  ? 135 TRP A CZ3  1 
ATOM 1852 C CH2  . TRP A 1 135 ? 118.999 92.436  115.977 1.00 44.07  ? 135 TRP A CH2  1 
ATOM 1853 H H    . TRP A 1 135 ? 123.915 92.681  111.835 1.00 52.10  ? 135 TRP A H    1 
ATOM 1854 H HA   . TRP A 1 135 ? 124.064 90.060  112.542 1.00 50.93  ? 135 TRP A HA   1 
ATOM 1855 H HB2  . TRP A 1 135 ? 121.840 91.535  111.696 1.00 51.88  ? 135 TRP A HB2  1 
ATOM 1856 H HB3  . TRP A 1 135 ? 121.847 89.958  111.508 1.00 53.50  ? 135 TRP A HB3  1 
ATOM 1857 H HD1  . TRP A 1 135 ? 122.726 88.896  114.150 1.00 51.36  ? 135 TRP A HD1  1 
ATOM 1858 H HE1  . TRP A 1 135 ? 121.535 89.223  116.215 1.00 53.22  ? 135 TRP A HE1  1 
ATOM 1859 H HE3  . TRP A 1 135 ? 120.059 92.811  112.915 1.00 49.16  ? 135 TRP A HE3  1 
ATOM 1860 H HZ2  . TRP A 1 135 ? 119.645 90.982  117.209 1.00 48.11  ? 135 TRP A HZ2  1 
ATOM 1861 H HZ3  . TRP A 1 135 ? 118.610 93.729  114.468 1.00 47.06  ? 135 TRP A HZ3  1 
ATOM 1862 H HH2  . TRP A 1 135 ? 118.410 92.823  116.583 1.00 45.12  ? 135 TRP A HH2  1 
ATOM 1863 N N    . ASP A 1 136 ? 125.214 90.909  109.993 1.00 56.11  ? 136 ASP A N    1 
ATOM 1864 C CA   . ASP A 1 136 ? 125.812 90.488  108.727 1.00 48.96  ? 136 ASP A CA   1 
ATOM 1865 C C    . ASP A 1 136 ? 124.759 90.368  107.628 1.00 50.30  ? 136 ASP A C    1 
ATOM 1866 O O    . ASP A 1 136 ? 124.673 89.364  106.919 1.00 50.08  ? 136 ASP A O    1 
ATOM 1867 C CB   . ASP A 1 136 ? 126.566 89.168  108.898 1.00 47.81  ? 136 ASP A CB   1 
ATOM 1868 C CG   . ASP A 1 136 ? 127.888 89.338  109.616 1.00 51.53  ? 136 ASP A CG   1 
ATOM 1869 O OD1  . ASP A 1 136 ? 128.447 90.454  109.585 1.00 60.94  ? 136 ASP A OD1  1 
ATOM 1870 O OD2  . ASP A 1 136 ? 128.370 88.353  110.212 1.00 52.86  ? 136 ASP A OD2  1 
ATOM 1871 H H    . ASP A 1 136 ? 125.610 91.582  110.353 1.00 54.34  ? 136 ASP A H    1 
ATOM 1872 H HA   . ASP A 1 136 ? 126.451 91.161  108.447 1.00 51.59  ? 136 ASP A HA   1 
ATOM 1873 H HB2  . ASP A 1 136 ? 126.020 88.556  109.416 1.00 51.38  ? 136 ASP A HB2  1 
ATOM 1874 H HB3  . ASP A 1 136 ? 126.748 88.792  108.023 1.00 50.84  ? 136 ASP A HB3  1 
ATOM 1875 N N    . LEU A 1 137 ? 123.947 91.413  107.487 1.00 52.06  ? 137 LEU A N    1 
ATOM 1876 C CA   . LEU A 1 137 ? 122.928 91.457  106.439 1.00 52.76  ? 137 LEU A CA   1 
ATOM 1877 C C    . LEU A 1 137 ? 123.538 91.959  105.129 1.00 51.08  ? 137 LEU A C    1 
ATOM 1878 O O    . LEU A 1 137 ? 123.147 92.984  104.572 1.00 51.24  ? 137 LEU A O    1 
ATOM 1879 C CB   . LEU A 1 137 ? 121.757 92.330  106.875 1.00 50.50  ? 137 LEU A CB   1 
ATOM 1880 C CG   . LEU A 1 137 ? 121.112 91.962  108.210 1.00 49.13  ? 137 LEU A CG   1 
ATOM 1881 C CD1  . LEU A 1 137 ? 120.004 92.942  108.550 1.00 49.15  ? 137 LEU A CD1  1 
ATOM 1882 C CD2  . LEU A 1 137 ? 120.581 90.541  108.173 1.00 51.66  ? 137 LEU A CD2  1 
ATOM 1883 H H    . LEU A 1 137 ? 123.964 92.111  107.988 1.00 51.73  ? 137 LEU A H    1 
ATOM 1884 H HA   . LEU A 1 137 ? 122.592 90.560  106.287 1.00 51.35  ? 137 LEU A HA   1 
ATOM 1885 H HB2  . LEU A 1 137 ? 122.072 93.244  106.948 1.00 50.57  ? 137 LEU A HB2  1 
ATOM 1886 H HB3  . LEU A 1 137 ? 121.068 92.279  106.195 1.00 50.57  ? 137 LEU A HB3  1 
ATOM 1887 H HG   . LEU A 1 137 ? 121.782 92.014  108.910 1.00 50.18  ? 137 LEU A HG   1 
ATOM 1888 H HD11 . LEU A 1 137 ? 119.323 92.902  107.860 1.00 48.81  ? 137 LEU A HD11 1 
ATOM 1889 H HD12 . LEU A 1 137 ? 119.622 92.702  109.408 1.00 48.70  ? 137 LEU A HD12 1 
ATOM 1890 H HD13 . LEU A 1 137 ? 120.377 93.837  108.594 1.00 50.33  ? 137 LEU A HD13 1 
ATOM 1891 H HD21 . LEU A 1 137 ? 121.327 89.927  108.094 1.00 52.22  ? 137 LEU A HD21 1 
ATOM 1892 H HD22 . LEU A 1 137 ? 120.095 90.366  108.994 1.00 51.54  ? 137 LEU A HD22 1 
ATOM 1893 H HD23 . LEU A 1 137 ? 119.989 90.446  107.411 1.00 52.77  ? 137 LEU A HD23 1 
ATOM 1894 N N    . VAL A 1 138 ? 124.520 91.202  104.640 1.00 50.73  ? 138 VAL A N    1 
ATOM 1895 C CA   . VAL A 1 138 ? 125.222 91.518  103.403 1.00 53.25  ? 138 VAL A CA   1 
ATOM 1896 C C    . VAL A 1 138 ? 125.394 90.238  102.596 1.00 60.09  ? 138 VAL A C    1 
ATOM 1897 O O    . VAL A 1 138 ? 125.217 89.127  103.098 1.00 69.26  ? 138 VAL A O    1 
ATOM 1898 C CB   . VAL A 1 138 ? 126.596 92.173  103.656 1.00 50.26  ? 138 VAL A CB   1 
ATOM 1899 C CG1  . VAL A 1 138 ? 126.437 93.450  104.465 1.00 50.55  ? 138 VAL A CG1  1 
ATOM 1900 C CG2  . VAL A 1 138 ? 127.530 91.196  104.358 1.00 51.50  ? 138 VAL A CG2  1 
ATOM 1901 H H    . VAL A 1 138 ? 124.801 90.482  105.017 1.00 52.20  ? 138 VAL A H    1 
ATOM 1902 H HA   . VAL A 1 138 ? 124.685 92.134  102.882 1.00 53.95  ? 138 VAL A HA   1 
ATOM 1903 H HB   . VAL A 1 138 ? 126.995 92.406  102.803 1.00 52.18  ? 138 VAL A HB   1 
ATOM 1904 H HG11 . VAL A 1 138 ? 125.943 93.257  105.277 1.00 51.59  ? 138 VAL A HG11 1 
ATOM 1905 H HG12 . VAL A 1 138 ? 127.317 93.792  104.689 1.00 51.25  ? 138 VAL A HG12 1 
ATOM 1906 H HG13 . VAL A 1 138 ? 125.959 94.104  103.931 1.00 50.95  ? 138 VAL A HG13 1 
ATOM 1907 H HG21 . VAL A 1 138 ? 127.002 90.532  104.828 1.00 54.39  ? 138 VAL A HG21 1 
ATOM 1908 H HG22 . VAL A 1 138 ? 128.092 90.763  103.696 1.00 53.54  ? 138 VAL A HG22 1 
ATOM 1909 H HG23 . VAL A 1 138 ? 128.080 91.685  104.990 1.00 53.72  ? 138 VAL A HG23 1 
ATOM 1910 N N    . CYS A 1 139 ? 125.738 90.415  101.322 1.00 60.62  ? 139 CYS A N    1 
ATOM 1911 C CA   . CYS A 1 139 ? 125.997 89.308  100.412 1.00 64.26  ? 139 CYS A CA   1 
ATOM 1912 C C    . CYS A 1 139 ? 124.783 88.390  100.318 1.00 70.40  ? 139 CYS A C    1 
ATOM 1913 O O    . CYS A 1 139 ? 123.731 88.806  99.820  1.00 70.45  ? 139 CYS A O    1 
ATOM 1914 C CB   . CYS A 1 139 ? 127.233 88.535  100.875 1.00 63.91  ? 139 CYS A CB   1 
ATOM 1915 S SG   . CYS A 1 139 ? 128.709 89.562  101.088 1.00 92.76  ? 139 CYS A SG   1 
ATOM 1916 H H    . CYS A 1 139 ? 125.827 91.186  100.952 1.00 60.68  ? 139 CYS A H    1 
ATOM 1917 H HA   . CYS A 1 139 ? 126.168 89.659  99.524  1.00 65.80  ? 139 CYS A HA   1 
ATOM 1918 H HB2  . CYS A 1 139 ? 127.043 88.125  101.733 1.00 65.82  ? 139 CYS A HB2  1 
ATOM 1919 H HB3  . CYS A 1 139 ? 127.436 87.850  100.219 1.00 66.13  ? 139 CYS A HB3  1 
ATOM 1920 N N    . ASP A 1 140 ? 124.881 87.169  100.853 1.00 69.01  ? 140 ASP A N    1 
ATOM 1921 C CA   . ASP A 1 140 ? 123.781 86.221  100.733 1.00 65.62  ? 140 ASP A CA   1 
ATOM 1922 C C    . ASP A 1 140 ? 122.582 86.624  101.574 1.00 57.07  ? 140 ASP A C    1 
ATOM 1923 O O    . ASP A 1 140 ? 121.460 86.199  101.279 1.00 58.87  ? 140 ASP A O    1 
ATOM 1924 C CB   . ASP A 1 140 ? 124.240 84.819  101.139 1.00 66.88  ? 140 ASP A CB   1 
ATOM 1925 C CG   . ASP A 1 140 ? 124.416 83.890  99.952  1.00 69.75  ? 140 ASP A CG   1 
ATOM 1926 O OD1  . ASP A 1 140 ? 123.716 84.068  98.934  1.00 72.39  ? 140 ASP A OD1  1 
ATOM 1927 O OD2  . ASP A 1 140 ? 125.257 82.970  100.044 1.00 67.09  ? 140 ASP A OD2  1 
ATOM 1928 H H    . ASP A 1 140 ? 125.559 86.863  101.284 1.00 67.72  ? 140 ASP A H    1 
ATOM 1929 H HA   . ASP A 1 140 ? 123.493 86.195  99.808  1.00 66.78  ? 140 ASP A HA   1 
ATOM 1930 H HB2  . ASP A 1 140 ? 125.094 84.885  101.594 1.00 67.86  ? 140 ASP A HB2  1 
ATOM 1931 H HB3  . ASP A 1 140 ? 123.576 84.428  101.728 1.00 65.60  ? 140 ASP A HB3  1 
ATOM 1932 N N    . SER A 1 141 ? 122.795 87.429  102.607 1.00 52.47  ? 141 SER A N    1 
ATOM 1933 C CA   . SER A 1 141 ? 121.718 87.965  103.420 1.00 55.52  ? 141 SER A CA   1 
ATOM 1934 C C    . SER A 1 141 ? 121.267 89.341  102.948 1.00 58.02  ? 141 SER A C    1 
ATOM 1935 O O    . SER A 1 141 ? 120.459 89.980  103.628 1.00 62.68  ? 141 SER A O    1 
ATOM 1936 C CB   . SER A 1 141 ? 122.157 88.037  104.884 1.00 61.78  ? 141 SER A CB   1 
ATOM 1937 O OG   . SER A 1 141 ? 122.615 86.776  105.339 1.00 67.08  ? 141 SER A OG   1 
ATOM 1938 H H    . SER A 1 141 ? 123.577 87.680  102.862 1.00 58.94  ? 141 SER A H    1 
ATOM 1939 H HA   . SER A 1 141 ? 120.957 87.364  103.371 1.00 57.71  ? 141 SER A HA   1 
ATOM 1940 H HB2  . SER A 1 141 ? 122.877 88.682  104.959 1.00 58.95  ? 141 SER A HB2  1 
ATOM 1941 H HB3  . SER A 1 141 ? 121.403 88.312  105.429 1.00 59.19  ? 141 SER A HB3  1 
ATOM 1942 H HG   . SER A 1 141 ? 122.853 86.830  106.143 1.00 62.57  ? 141 SER A HG   1 
ATOM 1943 N N    . GLN A 1 142 ? 121.767 89.812  101.800 1.00 53.63  ? 142 GLN A N    1 
ATOM 1944 C CA   . GLN A 1 142 ? 121.401 91.149  101.345 1.00 61.69  ? 142 GLN A CA   1 
ATOM 1945 C C    . GLN A 1 142 ? 119.886 91.292  101.249 1.00 64.43  ? 142 GLN A C    1 
ATOM 1946 O O    . GLN A 1 142 ? 119.314 92.280  101.727 1.00 62.23  ? 142 GLN A O    1 
ATOM 1947 C CB   . GLN A 1 142 ? 122.064 91.436  99.997  1.00 65.18  ? 142 GLN A CB   1 
ATOM 1948 C CG   . GLN A 1 142 ? 121.269 92.323  99.050  1.00 71.82  ? 142 GLN A CG   1 
ATOM 1949 C CD   . GLN A 1 142 ? 122.163 93.084  98.094  1.00 79.94  ? 142 GLN A CD   1 
ATOM 1950 O OE1  . GLN A 1 142 ? 123.243 92.617  97.732  1.00 75.22  ? 142 GLN A OE1  1 
ATOM 1951 N NE2  . GLN A 1 142 ? 121.718 94.263  97.678  1.00 82.45  ? 142 GLN A NE2  1 
ATOM 1952 H H    . GLN A 1 142 ? 122.302 89.387  101.279 1.00 58.04  ? 142 GLN A H    1 
ATOM 1953 H HA   . GLN A 1 142 ? 121.728 91.800  101.986 1.00 60.14  ? 142 GLN A HA   1 
ATOM 1954 H HB2  . GLN A 1 142 ? 122.916 91.872  100.159 1.00 64.37  ? 142 GLN A HB2  1 
ATOM 1955 H HB3  . GLN A 1 142 ? 122.213 90.595  99.540  1.00 65.13  ? 142 GLN A HB3  1 
ATOM 1956 H HG2  . GLN A 1 142 ? 120.661 91.774  98.530  1.00 70.13  ? 142 GLN A HG2  1 
ATOM 1957 H HG3  . GLN A 1 142 ? 120.775 92.983  99.560  1.00 70.84  ? 142 GLN A HG3  1 
ATOM 1958 H HE21 . GLN A 1 142 ? 120.957 94.556  97.953  1.00 77.72  ? 142 GLN A HE21 1 
ATOM 1959 H HE22 . GLN A 1 142 ? 122.190 94.733  97.135  1.00 80.90  ? 142 GLN A HE22 1 
ATOM 1960 N N    . ALA A 1 143 ? 119.216 90.294  100.672 1.00 63.86  ? 143 ALA A N    1 
ATOM 1961 C CA   . ALA A 1 143 ? 117.773 90.371  100.489 1.00 61.67  ? 143 ALA A CA   1 
ATOM 1962 C C    . ALA A 1 143 ? 117.027 90.531  101.806 1.00 62.19  ? 143 ALA A C    1 
ATOM 1963 O O    . ALA A 1 143 ? 115.885 91.002  101.802 1.00 62.92  ? 143 ALA A O    1 
ATOM 1964 C CB   . ALA A 1 143 ? 117.270 89.124  99.763  1.00 57.42  ? 143 ALA A CB   1 
ATOM 1965 H H    . ALA A 1 143 ? 119.573 89.567  100.383 1.00 62.80  ? 143 ALA A H    1 
ATOM 1966 H HA   . ALA A 1 143 ? 117.568 91.142  99.937  1.00 62.06  ? 143 ALA A HA   1 
ATOM 1967 H HB1  . ALA A 1 143 ? 117.487 88.341  100.292 1.00 58.73  ? 143 ALA A HB1  1 
ATOM 1968 H HB2  . ALA A 1 143 ? 116.308 89.192  99.653  1.00 57.14  ? 143 ALA A HB2  1 
ATOM 1969 H HB3  . ALA A 1 143 ? 117.700 89.068  98.896  1.00 58.75  ? 143 ALA A HB3  1 
ATOM 1970 N N    . LEU A 1 144 ? 117.636 90.152  102.930 1.00 59.93  ? 144 LEU A N    1 
ATOM 1971 C CA   . LEU A 1 144 ? 116.966 90.299  104.215 1.00 54.16  ? 144 LEU A CA   1 
ATOM 1972 C C    . LEU A 1 144 ? 116.783 91.754  104.620 1.00 55.63  ? 144 LEU A C    1 
ATOM 1973 O O    . LEU A 1 144 ? 116.023 92.022  105.557 1.00 56.45  ? 144 LEU A O    1 
ATOM 1974 C CB   . LEU A 1 144 ? 117.745 89.561  105.304 1.00 49.69  ? 144 LEU A CB   1 
ATOM 1975 C CG   . LEU A 1 144 ? 117.234 88.161  105.643 1.00 48.65  ? 144 LEU A CG   1 
ATOM 1976 C CD1  . LEU A 1 144 ? 117.523 87.194  104.509 1.00 54.30  ? 144 LEU A CD1  1 
ATOM 1977 C CD2  . LEU A 1 144 ? 117.864 87.670  106.935 1.00 52.53  ? 144 LEU A CD2  1 
ATOM 1978 H H    . LEU A 1 144 ? 118.425 89.811  102.973 1.00 59.56  ? 144 LEU A H    1 
ATOM 1979 H HA   . LEU A 1 144 ? 116.086 89.896  104.157 1.00 55.71  ? 144 LEU A HA   1 
ATOM 1980 H HB2  . LEU A 1 144 ? 118.666 89.471  105.023 1.00 54.51  ? 144 LEU A HB2  1 
ATOM 1981 H HB3  . LEU A 1 144 ? 117.707 90.087  106.118 1.00 52.77  ? 144 LEU A HB3  1 
ATOM 1982 H HG   . LEU A 1 144 ? 116.273 88.197  105.772 1.00 50.50  ? 144 LEU A HG   1 
ATOM 1983 H HD11 . LEU A 1 144 ? 117.212 86.310  104.762 1.00 54.26  ? 144 LEU A HD11 1 
ATOM 1984 H HD12 . LEU A 1 144 ? 117.057 87.494  103.713 1.00 55.53  ? 144 LEU A HD12 1 
ATOM 1985 H HD13 . LEU A 1 144 ? 118.479 87.174  104.346 1.00 55.18  ? 144 LEU A HD13 1 
ATOM 1986 H HD21 . LEU A 1 144 ? 117.529 86.781  107.131 1.00 53.34  ? 144 LEU A HD21 1 
ATOM 1987 H HD22 . LEU A 1 144 ? 118.827 87.645  106.826 1.00 52.61  ? 144 LEU A HD22 1 
ATOM 1988 H HD23 . LEU A 1 144 ? 117.627 88.278  107.653 1.00 52.26  ? 144 LEU A HD23 1 
ATOM 1989 N N    . LYS A 1 145 ? 117.446 92.696  103.950 1.00 54.76  ? 145 LYS A N    1 
ATOM 1990 C CA   . LYS A 1 145 ? 117.302 94.095  104.332 1.00 58.48  ? 145 LYS A CA   1 
ATOM 1991 C C    . LYS A 1 145 ? 115.955 94.644  103.875 1.00 61.58  ? 145 LYS A C    1 
ATOM 1992 O O    . LYS A 1 145 ? 115.188 95.147  104.707 1.00 58.74  ? 145 LYS A O    1 
ATOM 1993 C CB   . LYS A 1 145 ? 118.443 94.939  103.762 1.00 61.14  ? 145 LYS A CB   1 
ATOM 1994 C CG   . LYS A 1 145 ? 118.813 96.120  104.638 1.00 59.68  ? 145 LYS A CG   1 
ATOM 1995 C CD   . LYS A 1 145 ? 118.154 97.407  104.169 1.00 64.77  ? 145 LYS A CD   1 
ATOM 1996 C CE   . LYS A 1 145 ? 119.089 98.579  104.348 1.00 71.51  ? 145 LYS A CE   1 
ATOM 1997 N NZ   . LYS A 1 145 ? 118.400 99.889  104.199 1.00 74.56  ? 145 LYS A NZ   1 
ATOM 1998 H H    . LYS A 1 145 ? 117.974 92.554  103.287 1.00 57.35  ? 145 LYS A H    1 
ATOM 1999 H HA   . LYS A 1 145 ? 117.335 94.155  105.299 1.00 57.73  ? 145 LYS A HA   1 
ATOM 2000 H HB2  . LYS A 1 145 ? 119.231 94.378  103.678 1.00 60.55  ? 145 LYS A HB2  1 
ATOM 2001 H HB3  . LYS A 1 145 ? 118.194 95.280  102.893 1.00 62.00  ? 145 LYS A HB3  1 
ATOM 2002 H HG2  . LYS A 1 145 ? 118.528 95.950  105.550 1.00 59.89  ? 145 LYS A HG2  1 
ATOM 2003 H HG3  . LYS A 1 145 ? 119.774 96.247  104.609 1.00 60.29  ? 145 LYS A HG3  1 
ATOM 2004 H HD2  . LYS A 1 145 ? 117.927 97.346  103.228 1.00 63.62  ? 145 LYS A HD2  1 
ATOM 2005 H HD3  . LYS A 1 145 ? 117.357 97.570  104.697 1.00 63.96  ? 145 LYS A HD3  1 
ATOM 2006 H HE2  . LYS A 1 145 ? 119.467 98.528  105.237 1.00 68.28  ? 145 LYS A HE2  1 
ATOM 2007 H HE3  . LYS A 1 145 ? 119.792 98.531  103.682 1.00 68.19  ? 145 LYS A HE3  1 
ATOM 2008 H HZ1  . LYS A 1 145 ? 118.982 100.553 104.319 1.00 71.79  ? 145 LYS A HZ1  1 
ATOM 2009 H HZ2  . LYS A 1 145 ? 118.047 99.957  103.385 1.00 69.04  ? 145 LYS A HZ2  1 
ATOM 2010 H HZ3  . LYS A 1 145 ? 117.751 99.961  104.804 1.00 71.81  ? 145 LYS A HZ3  1 
ATOM 2011 N N    . PRO A 1 146 ? 115.618 94.580  102.582 1.00 64.65  ? 146 PRO A N    1 
ATOM 2012 C CA   . PRO A 1 146 ? 114.284 95.048  102.173 1.00 59.23  ? 146 PRO A CA   1 
ATOM 2013 C C    . PRO A 1 146 ? 113.166 94.292  102.860 1.00 58.45  ? 146 PRO A C    1 
ATOM 2014 O O    . PRO A 1 146 ? 112.109 94.872  103.137 1.00 59.74  ? 146 PRO A O    1 
ATOM 2015 C CB   . PRO A 1 146 ? 114.269 94.816  100.654 1.00 60.57  ? 146 PRO A CB   1 
ATOM 2016 C CG   . PRO A 1 146 ? 115.403 93.910  100.370 1.00 62.87  ? 146 PRO A CG   1 
ATOM 2017 C CD   . PRO A 1 146 ? 116.419 94.129  101.431 1.00 65.82  ? 146 PRO A CD   1 
ATOM 2018 H HA   . PRO A 1 146 ? 114.191 95.997  102.352 1.00 59.74  ? 146 PRO A HA   1 
ATOM 2019 H HB2  . PRO A 1 146 ? 113.430 94.402  100.398 1.00 61.72  ? 146 PRO A HB2  1 
ATOM 2020 H HB3  . PRO A 1 146 ? 114.386 95.662  100.196 1.00 60.20  ? 146 PRO A HB3  1 
ATOM 2021 H HG2  . PRO A 1 146 ? 115.090 92.992  100.391 1.00 62.35  ? 146 PRO A HG2  1 
ATOM 2022 H HG3  . PRO A 1 146 ? 115.772 94.120  99.498  1.00 62.28  ? 146 PRO A HG3  1 
ATOM 2023 H HD2  . PRO A 1 146 ? 116.872 93.297  101.628 1.00 62.51  ? 146 PRO A HD2  1 
ATOM 2024 H HD3  . PRO A 1 146 ? 117.040 94.819  101.153 1.00 63.72  ? 146 PRO A HD3  1 
ATOM 2025 N N    . MET A 1 147 ? 113.376 93.006  103.147 1.00 57.92  ? 147 MET A N    1 
ATOM 2026 C CA   . MET A 1 147 ? 112.353 92.209  103.814 1.00 56.86  ? 147 MET A CA   1 
ATOM 2027 C C    . MET A 1 147 ? 111.937 92.840  105.136 1.00 57.09  ? 147 MET A C    1 
ATOM 2028 O O    . MET A 1 147 ? 110.743 93.016  105.406 1.00 59.93  ? 147 MET A O    1 
ATOM 2029 C CB   . MET A 1 147 ? 112.876 90.789  104.029 1.00 55.61  ? 147 MET A CB   1 
ATOM 2030 C CG   . MET A 1 147 ? 111.821 89.708  103.904 1.00 65.29  ? 147 MET A CG   1 
ATOM 2031 S SD   . MET A 1 147 ? 112.057 88.410  105.135 1.00 80.53  ? 147 MET A SD   1 
ATOM 2032 C CE   . MET A 1 147 ? 111.745 89.314  106.646 1.00 70.22  ? 147 MET A CE   1 
ATOM 2033 H H    . MET A 1 147 ? 114.100 92.578  102.966 1.00 58.89  ? 147 MET A H    1 
ATOM 2034 H HA   . MET A 1 147 ? 111.578 92.151  103.234 1.00 58.76  ? 147 MET A HA   1 
ATOM 2035 H HB2  . MET A 1 147 ? 113.561 90.606  103.367 1.00 57.32  ? 147 MET A HB2  1 
ATOM 2036 H HB3  . MET A 1 147 ? 113.260 90.735  104.919 1.00 58.77  ? 147 MET A HB3  1 
ATOM 2037 H HG2  . MET A 1 147 ? 110.944 90.103  104.037 1.00 64.33  ? 147 MET A HG2  1 
ATOM 2038 H HG3  . MET A 1 147 ? 111.874 89.305  103.023 1.00 65.09  ? 147 MET A HG3  1 
ATOM 2039 H HE1  . MET A 1 147 ? 111.505 88.687  107.347 1.00 70.44  ? 147 MET A HE1  1 
ATOM 2040 H HE2  . MET A 1 147 ? 112.547 89.800  106.897 1.00 70.91  ? 147 MET A HE2  1 
ATOM 2041 H HE3  . MET A 1 147 ? 111.020 89.936  106.488 1.00 70.91  ? 147 MET A HE3  1 
ATOM 2042 N N    . ALA A 1 148 ? 112.914 93.208  105.969 1.00 53.43  ? 148 ALA A N    1 
ATOM 2043 C CA   . ALA A 1 148 ? 112.593 93.873  107.225 1.00 52.76  ? 148 ALA A CA   1 
ATOM 2044 C C    . ALA A 1 148 ? 111.791 95.143  106.989 1.00 54.31  ? 148 ALA A C    1 
ATOM 2045 O O    . ALA A 1 148 ? 110.934 95.498  107.805 1.00 55.71  ? 148 ALA A O    1 
ATOM 2046 C CB   . ALA A 1 148 ? 113.874 94.195  107.994 1.00 50.84  ? 148 ALA A CB   1 
ATOM 2047 H H    . ALA A 1 148 ? 113.754 93.082  105.831 1.00 56.07  ? 148 ALA A H    1 
ATOM 2048 H HA   . ALA A 1 148 ? 112.057 93.275  107.770 1.00 54.14  ? 148 ALA A HA   1 
ATOM 2049 H HB1  . ALA A 1 148 ? 114.437 94.765  107.446 1.00 54.57  ? 148 ALA A HB1  1 
ATOM 2050 H HB2  . ALA A 1 148 ? 113.639 94.653  108.816 1.00 51.17  ? 148 ALA A HB2  1 
ATOM 2051 H HB3  . ALA A 1 148 ? 114.337 93.367  108.195 1.00 52.56  ? 148 ALA A HB3  1 
ATOM 2052 N N    . GLN A 1 149 ? 112.050 95.838  105.881 1.00 54.63  ? 149 GLN A N    1 
ATOM 2053 C CA   . GLN A 1 149 ? 111.281 97.037  105.573 1.00 55.11  ? 149 GLN A CA   1 
ATOM 2054 C C    . GLN A 1 149 ? 109.844 96.699  105.203 1.00 56.31  ? 149 GLN A C    1 
ATOM 2055 O O    . GLN A 1 149 ? 108.928 97.463  105.524 1.00 54.64  ? 149 GLN A O    1 
ATOM 2056 C CB   . GLN A 1 149 ? 111.950 97.813  104.440 1.00 57.90  ? 149 GLN A CB   1 
ATOM 2057 C CG   . GLN A 1 149 ? 112.738 99.020  104.904 1.00 60.62  ? 149 GLN A CG   1 
ATOM 2058 C CD   . GLN A 1 149 ? 113.957 99.289  104.047 1.00 69.14  ? 149 GLN A CD   1 
ATOM 2059 O OE1  . GLN A 1 149 ? 113.886 99.246  102.820 1.00 70.87  ? 149 GLN A OE1  1 
ATOM 2060 N NE2  . GLN A 1 149 ? 115.091 99.554  104.691 1.00 66.27  ? 149 GLN A NE2  1 
ATOM 2061 H H    . GLN A 1 149 ? 112.656 95.636  105.304 1.00 56.40  ? 149 GLN A H    1 
ATOM 2062 H HA   . GLN A 1 149 ? 111.259 97.611  106.355 1.00 56.48  ? 149 GLN A HA   1 
ATOM 2063 H HB2  . GLN A 1 149 ? 112.560 97.222  103.972 1.00 59.44  ? 149 GLN A HB2  1 
ATOM 2064 H HB3  . GLN A 1 149 ? 111.264 98.129  103.832 1.00 58.75  ? 149 GLN A HB3  1 
ATOM 2065 H HG2  . GLN A 1 149 ? 112.161 99.795  104.866 1.00 60.98  ? 149 GLN A HG2  1 
ATOM 2066 H HG3  . GLN A 1 149 ? 113.039 98.871  105.812 1.00 60.04  ? 149 GLN A HG3  1 
ATOM 2067 H HE21 . GLN A 1 149 ? 115.112 99.574  105.550 1.00 64.41  ? 149 GLN A HE21 1 
ATOM 2068 H HE22 . GLN A 1 149 ? 115.809 99.709  104.244 1.00 68.02  ? 149 GLN A HE22 1 
ATOM 2069 N N    . SER A 1 150 ? 109.624 95.569  104.528 1.00 55.98  ? 150 SER A N    1 
ATOM 2070 C CA   . SER A 1 150 ? 108.273 95.210  104.110 1.00 49.29  ? 150 SER A CA   1 
ATOM 2071 C C    . SER A 1 150 ? 107.412 94.806  105.303 1.00 54.15  ? 150 SER A C    1 
ATOM 2072 O O    . SER A 1 150 ? 106.274 95.270  105.444 1.00 60.32  ? 150 SER A O    1 
ATOM 2073 C CB   . SER A 1 150 ? 108.330 94.086  103.077 1.00 47.74  ? 150 SER A CB   1 
ATOM 2074 O OG   . SER A 1 150 ? 107.129 93.335  103.075 1.00 52.46  ? 150 SER A OG   1 
ATOM 2075 H H    . SER A 1 150 ? 110.232 95.003  104.302 1.00 56.43  ? 150 SER A H    1 
ATOM 2076 H HA   . SER A 1 150 ? 107.857 95.979  103.689 1.00 51.39  ? 150 SER A HA   1 
ATOM 2077 H HB2  . SER A 1 150 ? 108.460 94.473  102.198 1.00 50.05  ? 150 SER A HB2  1 
ATOM 2078 H HB3  . SER A 1 150 ? 109.071 93.499  103.293 1.00 52.31  ? 150 SER A HB3  1 
ATOM 2079 H HG   . SER A 1 150 ? 107.173 92.729  102.496 1.00 54.55  ? 150 SER A HG   1 
ATOM 2080 N N    . ILE A 1 151 ? 107.948 93.961  106.187 1.00 53.02  ? 151 ILE A N    1 
ATOM 2081 C CA   . ILE A 1 151 ? 107.167 93.481  107.326 1.00 50.58  ? 151 ILE A CA   1 
ATOM 2082 C C    . ILE A 1 151 ? 106.621 94.655  108.127 1.00 49.47  ? 151 ILE A C    1 
ATOM 2083 O O    . ILE A 1 151 ? 105.441 94.682  108.494 1.00 52.65  ? 151 ILE A O    1 
ATOM 2084 C CB   . ILE A 1 151 ? 108.015 92.546  108.209 1.00 50.11  ? 151 ILE A CB   1 
ATOM 2085 C CG1  . ILE A 1 151 ? 108.034 91.136  107.618 1.00 56.52  ? 151 ILE A CG1  1 
ATOM 2086 C CG2  . ILE A 1 151 ? 107.483 92.529  109.638 1.00 44.87  ? 151 ILE A CG2  1 
ATOM 2087 C CD1  . ILE A 1 151 ? 109.038 90.208  108.268 1.00 53.84  ? 151 ILE A CD1  1 
ATOM 2088 H H    . ILE A 1 151 ? 108.751 93.653  106.147 1.00 53.66  ? 151 ILE A H    1 
ATOM 2089 H HA   . ILE A 1 151 ? 106.413 92.968  106.995 1.00 51.64  ? 151 ILE A HA   1 
ATOM 2090 H HB   . ILE A 1 151 ? 108.924 92.883  108.225 1.00 51.99  ? 151 ILE A HB   1 
ATOM 2091 H HG12 . ILE A 1 151 ? 107.155 90.742  107.728 1.00 55.18  ? 151 ILE A HG12 1 
ATOM 2092 H HG13 . ILE A 1 151 ? 108.251 91.197  106.674 1.00 55.10  ? 151 ILE A HG13 1 
ATOM 2093 H HG21 . ILE A 1 151 ? 106.518 92.435  109.614 1.00 47.23  ? 151 ILE A HG21 1 
ATOM 2094 H HG22 . ILE A 1 151 ? 107.872 91.781  110.115 1.00 46.76  ? 151 ILE A HG22 1 
ATOM 2095 H HG23 . ILE A 1 151 ? 107.727 93.357  110.081 1.00 48.04  ? 151 ILE A HG23 1 
ATOM 2096 H HD11 . ILE A 1 151 ? 109.100 89.394  107.744 1.00 54.96  ? 151 ILE A HD11 1 
ATOM 2097 H HD12 . ILE A 1 151 ? 109.902 90.647  108.303 1.00 54.81  ? 151 ILE A HD12 1 
ATOM 2098 H HD13 . ILE A 1 151 ? 108.739 89.997  109.166 1.00 53.70  ? 151 ILE A HD13 1 
ATOM 2099 N N    . TYR A 1 152 ? 107.469 95.646  108.407 1.00 44.69  ? 152 TYR A N    1 
ATOM 2100 C CA   . TYR A 1 152 ? 107.000 96.822  109.129 1.00 46.64  ? 152 TYR A CA   1 
ATOM 2101 C C    . TYR A 1 152 ? 105.759 97.390  108.458 1.00 49.96  ? 152 TYR A C    1 
ATOM 2102 O O    . TYR A 1 152 ? 104.716 97.568  109.097 1.00 59.67  ? 152 TYR A O    1 
ATOM 2103 C CB   . TYR A 1 152 ? 108.113 97.869  109.192 1.00 52.13  ? 152 TYR A CB   1 
ATOM 2104 C CG   . TYR A 1 152 ? 107.683 99.219  109.727 1.00 54.37  ? 152 TYR A CG   1 
ATOM 2105 C CD1  . TYR A 1 152 ? 107.669 99.474  111.091 1.00 56.60  ? 152 TYR A CD1  1 
ATOM 2106 C CD2  . TYR A 1 152 ? 107.303 100.243 108.868 1.00 58.09  ? 152 TYR A CD2  1 
ATOM 2107 C CE1  . TYR A 1 152 ? 107.284 100.705 111.587 1.00 62.18  ? 152 TYR A CE1  1 
ATOM 2108 C CE2  . TYR A 1 152 ? 106.915 101.478 109.355 1.00 62.33  ? 152 TYR A CE2  1 
ATOM 2109 C CZ   . TYR A 1 152 ? 106.908 101.703 110.715 1.00 66.62  ? 152 TYR A CZ   1 
ATOM 2110 O OH   . TYR A 1 152 ? 106.525 102.929 111.206 1.00 68.70  ? 152 TYR A OH   1 
ATOM 2111 H H    . TYR A 1 152 ? 108.301 95.663  108.192 1.00 49.75  ? 152 TYR A H    1 
ATOM 2112 H HA   . TYR A 1 152 ? 106.765 96.570  110.036 1.00 49.63  ? 152 TYR A HA   1 
ATOM 2113 H HB2  . TYR A 1 152 ? 108.819 97.537  109.768 1.00 53.14  ? 152 TYR A HB2  1 
ATOM 2114 H HB3  . TYR A 1 152 ? 108.458 98.005  108.296 1.00 54.29  ? 152 TYR A HB3  1 
ATOM 2115 H HD1  . TYR A 1 152 ? 107.922 98.803  111.683 1.00 57.23  ? 152 TYR A HD1  1 
ATOM 2116 H HD2  . TYR A 1 152 ? 107.307 100.094 107.950 1.00 58.44  ? 152 TYR A HD2  1 
ATOM 2117 H HE1  . TYR A 1 152 ? 107.279 100.859 112.504 1.00 62.29  ? 152 TYR A HE1  1 
ATOM 2118 H HE2  . TYR A 1 152 ? 106.661 102.154 108.769 1.00 62.65  ? 152 TYR A HE2  1 
ATOM 2119 H HH   . TYR A 1 152 ? 106.311 103.438 110.572 1.00 66.11  ? 152 TYR A HH   1 
ATOM 2120 N N    . LEU A 1 153 ? 105.836 97.616  107.145 1.00 45.24  ? 153 LEU A N    1 
ATOM 2121 C CA   . LEU A 1 153 ? 104.682 98.149  106.435 1.00 48.07  ? 153 LEU A CA   1 
ATOM 2122 C C    . LEU A 1 153 ? 103.500 97.196  106.531 1.00 46.87  ? 153 LEU A C    1 
ATOM 2123 O O    . LEU A 1 153 ? 102.356 97.630  106.714 1.00 49.60  ? 153 LEU A O    1 
ATOM 2124 C CB   . LEU A 1 153 ? 105.045 98.423  104.976 1.00 50.21  ? 153 LEU A CB   1 
ATOM 2125 C CG   . LEU A 1 153 ? 105.990 99.606  104.744 1.00 52.20  ? 153 LEU A CG   1 
ATOM 2126 C CD1  . LEU A 1 153 ? 106.309 99.743  103.272 1.00 54.96  ? 153 LEU A CD1  1 
ATOM 2127 C CD2  . LEU A 1 153 ? 105.397 100.905 105.277 1.00 55.73  ? 153 LEU A CD2  1 
ATOM 2128 H H    . LEU A 1 153 ? 106.525 97.467  106.655 1.00 49.81  ? 153 LEU A H    1 
ATOM 2129 H HA   . LEU A 1 153 ? 104.423 98.987  106.851 1.00 49.89  ? 153 LEU A HA   1 
ATOM 2130 H HB2  . LEU A 1 153 ? 105.474 97.633  104.612 1.00 51.59  ? 153 LEU A HB2  1 
ATOM 2131 H HB3  . LEU A 1 153 ? 104.227 98.598  104.483 1.00 50.15  ? 153 LEU A HB3  1 
ATOM 2132 H HG   . LEU A 1 153 ? 106.821 99.444  105.217 1.00 52.79  ? 153 LEU A HG   1 
ATOM 2133 H HD11 . LEU A 1 153 ? 105.517 100.060 102.812 1.00 55.88  ? 153 LEU A HD11 1 
ATOM 2134 H HD12 . LEU A 1 153 ? 107.032 100.379 103.163 1.00 53.83  ? 153 LEU A HD12 1 
ATOM 2135 H HD13 . LEU A 1 153 ? 106.574 98.878  102.923 1.00 55.12  ? 153 LEU A HD13 1 
ATOM 2136 H HD21 . LEU A 1 153 ? 104.482 100.987 104.963 1.00 54.33  ? 153 LEU A HD21 1 
ATOM 2137 H HD22 . LEU A 1 153 ? 105.413 100.890 106.246 1.00 54.76  ? 153 LEU A HD22 1 
ATOM 2138 H HD23 . LEU A 1 153 ? 105.927 101.649 104.953 1.00 55.38  ? 153 LEU A HD23 1 
ATOM 2139 N N    . ALA A 1 154 ? 103.759 95.888  106.444 1.00 44.66  ? 154 ALA A N    1 
ATOM 2140 C CA   . ALA A 1 154 ? 102.684 94.920  106.622 1.00 42.54  ? 154 ALA A CA   1 
ATOM 2141 C C    . ALA A 1 154 ? 101.930 95.186  107.914 1.00 48.47  ? 154 ALA A C    1 
ATOM 2142 O O    . ALA A 1 154 ? 100.692 95.178  107.935 1.00 52.93  ? 154 ALA A O    1 
ATOM 2143 C CB   . ALA A 1 154 ? 103.242 93.498  106.617 1.00 38.49  ? 154 ALA A CB   1 
ATOM 2144 H H    . ALA A 1 154 ? 104.531 95.545  106.285 1.00 48.63  ? 154 ALA A H    1 
ATOM 2145 H HA   . ALA A 1 154 ? 102.055 94.997  105.889 1.00 45.08  ? 154 ALA A HA   1 
ATOM 2146 H HB1  . ALA A 1 154 ? 103.731 93.345  105.794 1.00 43.12  ? 154 ALA A HB1  1 
ATOM 2147 H HB2  . ALA A 1 154 ? 103.832 93.386  107.377 1.00 44.49  ? 154 ALA A HB2  1 
ATOM 2148 H HB3  . ALA A 1 154 ? 102.503 92.873  106.682 1.00 40.87  ? 154 ALA A HB3  1 
ATOM 2149 N N    . GLY A 1 155 ? 102.658 95.468  108.997 1.00 50.04  ? 155 GLY A N    1 
ATOM 2150 C CA   . GLY A 1 155 ? 101.993 95.735  110.258 1.00 48.39  ? 155 GLY A CA   1 
ATOM 2151 C C    . GLY A 1 155 ? 100.980 96.852  110.137 1.00 48.81  ? 155 GLY A C    1 
ATOM 2152 O O    . GLY A 1 155 ? 99.838  96.722  110.587 1.00 53.49  ? 155 GLY A O    1 
ATOM 2153 H H    . GLY A 1 155 ? 103.515 95.509  109.022 1.00 50.15  ? 155 GLY A H    1 
ATOM 2154 H HA2  . GLY A 1 155 ? 101.534 94.935  110.550 1.00 48.62  ? 155 GLY A HA2  1 
ATOM 2155 H HA3  . GLY A 1 155 ? 102.653 95.974  110.929 1.00 49.26  ? 155 GLY A HA3  1 
ATOM 2156 N N    . ILE A 1 156 ? 101.361 97.941  109.469 1.00 43.01  ? 156 ILE A N    1 
ATOM 2157 C CA   . ILE A 1 156 ? 100.427 99.048  109.307 1.00 44.81  ? 156 ILE A CA   1 
ATOM 2158 C C    . ILE A 1 156 ? 99.140  98.547  108.666 1.00 46.43  ? 156 ILE A C    1 
ATOM 2159 O O    . ILE A 1 156 ? 98.036  98.830  109.150 1.00 52.47  ? 156 ILE A O    1 
ATOM 2160 C CB   . ILE A 1 156 ? 101.078 100.183 108.494 1.00 49.13  ? 156 ILE A CB   1 
ATOM 2161 C CG1  . ILE A 1 156 ? 102.425 100.560 109.120 1.00 53.51  ? 156 ILE A CG1  1 
ATOM 2162 C CG2  . ILE A 1 156 ? 100.158 101.393 108.416 1.00 50.14  ? 156 ILE A CG2  1 
ATOM 2163 C CD1  . ILE A 1 156 ? 102.931 101.931 108.743 1.00 57.16  ? 156 ILE A CD1  1 
ATOM 2164 H H    . ILE A 1 156 ? 102.133 98.050  109.107 1.00 46.74  ? 156 ILE A H    1 
ATOM 2165 H HA   . ILE A 1 156 ? 100.209 99.398  110.186 1.00 47.38  ? 156 ILE A HA   1 
ATOM 2166 H HB   . ILE A 1 156 ? 101.241 99.862  107.595 1.00 49.51  ? 156 ILE A HB   1 
ATOM 2167 H HG12 . ILE A 1 156 ? 102.331 100.540 110.085 1.00 53.13  ? 156 ILE A HG12 1 
ATOM 2168 H HG13 . ILE A 1 156 ? 103.091 99.914  108.841 1.00 51.98  ? 156 ILE A HG13 1 
ATOM 2169 H HG21 . ILE A 1 156 ? 100.503 102.006 107.747 1.00 49.48  ? 156 ILE A HG21 1 
ATOM 2170 H HG22 . ILE A 1 156 ? 99.267  101.108 108.164 1.00 49.45  ? 156 ILE A HG22 1 
ATOM 2171 H HG23 . ILE A 1 156 ? 100.135 101.827 109.282 1.00 49.30  ? 156 ILE A HG23 1 
ATOM 2172 H HD11 . ILE A 1 156 ? 103.834 102.034 109.078 1.00 54.16  ? 156 ILE A HD11 1 
ATOM 2173 H HD12 . ILE A 1 156 ? 102.920 102.017 107.777 1.00 56.79  ? 156 ILE A HD12 1 
ATOM 2174 H HD13 . ILE A 1 156 ? 102.358 102.603 109.143 1.00 56.38  ? 156 ILE A HD13 1 
ATOM 2175 N N    . LEU A 1 157 ? 99.261  97.729  107.619 1.00 42.42  ? 157 LEU A N    1 
ATOM 2176 C CA   . LEU A 1 157 ? 98.069  97.233  106.942 1.00 47.37  ? 157 LEU A CA   1 
ATOM 2177 C C    . LEU A 1 157 ? 97.183  96.447  107.898 1.00 48.44  ? 157 LEU A C    1 
ATOM 2178 O O    . LEU A 1 157 ? 95.955  96.578  107.861 1.00 49.98  ? 157 LEU A O    1 
ATOM 2179 C CB   . LEU A 1 157 ? 98.470  96.374  105.740 1.00 46.23  ? 157 LEU A CB   1 
ATOM 2180 C CG   . LEU A 1 157 ? 97.372  95.841  104.809 1.00 41.26  ? 157 LEU A CG   1 
ATOM 2181 C CD1  . LEU A 1 157 ? 96.575  94.712  105.452 1.00 40.35  ? 157 LEU A CD1  1 
ATOM 2182 C CD2  . LEU A 1 157 ? 96.446  96.964  104.368 1.00 42.07  ? 157 LEU A CD2  1 
ATOM 2183 H H    . LEU A 1 157 ? 100.007 97.457  107.288 1.00 45.67  ? 157 LEU A H    1 
ATOM 2184 H HA   . LEU A 1 157 ? 97.558  97.990  106.618 1.00 46.67  ? 157 LEU A HA   1 
ATOM 2185 H HB2  . LEU A 1 157 ? 99.053  96.917  105.189 1.00 45.41  ? 157 LEU A HB2  1 
ATOM 2186 H HB3  . LEU A 1 157 ? 98.964  95.608  106.069 1.00 46.70  ? 157 LEU A HB3  1 
ATOM 2187 H HG   . LEU A 1 157 ? 97.792  95.482  104.012 1.00 42.97  ? 157 LEU A HG   1 
ATOM 2188 H HD11 . LEU A 1 157 ? 96.253  94.117  104.757 1.00 40.69  ? 157 LEU A HD11 1 
ATOM 2189 H HD12 . LEU A 1 157 ? 97.151  94.226  106.062 1.00 42.29  ? 157 LEU A HD12 1 
ATOM 2190 H HD13 . LEU A 1 157 ? 95.825  95.091  105.937 1.00 42.57  ? 157 LEU A HD13 1 
ATOM 2191 H HD21 . LEU A 1 157 ? 95.826  96.619  103.706 1.00 43.45  ? 157 LEU A HD21 1 
ATOM 2192 H HD22 . LEU A 1 157 ? 95.958  97.294  105.138 1.00 41.38  ? 157 LEU A HD22 1 
ATOM 2193 H HD23 . LEU A 1 157 ? 96.978  97.677  103.981 1.00 41.48  ? 157 LEU A HD23 1 
ATOM 2194 N N    . VAL A 1 158 ? 97.778  95.622  108.764 1.00 43.84  ? 158 VAL A N    1 
ATOM 2195 C CA   . VAL A 1 158 ? 96.937  94.862  109.683 1.00 45.28  ? 158 VAL A CA   1 
ATOM 2196 C C    . VAL A 1 158 ? 96.358  95.785  110.746 1.00 48.95  ? 158 VAL A C    1 
ATOM 2197 O O    . VAL A 1 158 ? 95.235  95.569  111.218 1.00 50.67  ? 158 VAL A O    1 
ATOM 2198 C CB   . VAL A 1 158 ? 97.701  93.669  110.300 1.00 46.13  ? 158 VAL A CB   1 
ATOM 2199 C CG1  . VAL A 1 158 ? 98.526  92.948  109.238 1.00 47.97  ? 158 VAL A CG1  1 
ATOM 2200 C CG2  . VAL A 1 158 ? 98.577  94.086  111.477 1.00 43.69  ? 158 VAL A CG2  1 
ATOM 2201 H H    . VAL A 1 158 ? 98.625  95.495  108.839 1.00 46.05  ? 158 VAL A H    1 
ATOM 2202 H HA   . VAL A 1 158 ? 96.191  94.496  109.183 1.00 46.70  ? 158 VAL A HA   1 
ATOM 2203 H HB   . VAL A 1 158 ? 97.050  93.034  110.638 1.00 47.62  ? 158 VAL A HB   1 
ATOM 2204 H HG11 . VAL A 1 158 ? 98.941  92.170  109.641 1.00 49.02  ? 158 VAL A HG11 1 
ATOM 2205 H HG12 . VAL A 1 158 ? 97.939  92.671  108.518 1.00 48.06  ? 158 VAL A HG12 1 
ATOM 2206 H HG13 . VAL A 1 158 ? 99.210  93.544  108.897 1.00 45.49  ? 158 VAL A HG13 1 
ATOM 2207 H HG21 . VAL A 1 158 ? 98.922  93.283  111.900 1.00 45.99  ? 158 VAL A HG21 1 
ATOM 2208 H HG22 . VAL A 1 158 ? 99.315  94.618  111.152 1.00 43.72  ? 158 VAL A HG22 1 
ATOM 2209 H HG23 . VAL A 1 158 ? 98.055  94.585  112.121 1.00 44.72  ? 158 VAL A HG23 1 
ATOM 2210 N N    . GLY A 1 159 ? 97.094  96.832  111.129 1.00 51.75  ? 159 GLY A N    1 
ATOM 2211 C CA   . GLY A 1 159 ? 96.595  97.717  112.168 1.00 52.38  ? 159 GLY A CA   1 
ATOM 2212 C C    . GLY A 1 159 ? 95.252  98.321  111.810 1.00 51.44  ? 159 GLY A C    1 
ATOM 2213 O O    . GLY A 1 159 ? 94.285  98.218  112.570 1.00 53.51  ? 159 GLY A O    1 
ATOM 2214 H H    . GLY A 1 159 ? 97.866  97.039  110.811 1.00 50.34  ? 159 GLY A H    1 
ATOM 2215 H HA2  . GLY A 1 159 ? 96.496  97.221  112.996 1.00 51.48  ? 159 GLY A HA2  1 
ATOM 2216 H HA3  . GLY A 1 159 ? 97.227  98.439  112.313 1.00 50.50  ? 159 GLY A HA3  1 
ATOM 2217 N N    . ALA A 1 160 ? 95.163  98.925  110.623 1.00 47.33  ? 160 ALA A N    1 
ATOM 2218 C CA   . ALA A 1 160 ? 93.904  99.513  110.186 1.00 50.22  ? 160 ALA A CA   1 
ATOM 2219 C C    . ALA A 1 160 ? 92.805  98.470  110.045 1.00 48.02  ? 160 ALA A C    1 
ATOM 2220 O O    . ALA A 1 160 ? 91.624  98.832  110.021 1.00 49.63  ? 160 ALA A O    1 
ATOM 2221 C CB   . ALA A 1 160 ? 94.099  100.247 108.859 1.00 53.14  ? 160 ALA A CB   1 
ATOM 2222 H H    . ALA A 1 160 ? 95.809  99.006  110.062 1.00 48.39  ? 160 ALA A H    1 
ATOM 2223 H HA   . ALA A 1 160 ? 93.616  100.162 110.846 1.00 51.09  ? 160 ALA A HA   1 
ATOM 2224 H HB1  . ALA A 1 160 ? 93.250  100.626 108.585 1.00 52.47  ? 160 ALA A HB1  1 
ATOM 2225 H HB2  . ALA A 1 160 ? 94.753  100.954 108.981 1.00 52.31  ? 160 ALA A HB2  1 
ATOM 2226 H HB3  . ALA A 1 160 ? 94.413  99.617  108.191 1.00 50.13  ? 160 ALA A HB3  1 
ATOM 2227 N N    . ALA A 1 161 ? 93.161  97.188  109.950 1.00 48.45  ? 161 ALA A N    1 
ATOM 2228 C CA   . ALA A 1 161 ? 92.153  96.142  109.874 1.00 47.57  ? 161 ALA A CA   1 
ATOM 2229 C C    . ALA A 1 161 ? 91.605  95.761  111.242 1.00 49.54  ? 161 ALA A C    1 
ATOM 2230 O O    . ALA A 1 161 ? 90.494  95.225  111.320 1.00 45.71  ? 161 ALA A O    1 
ATOM 2231 C CB   . ALA A 1 161 ? 92.729  94.901  109.190 1.00 48.77  ? 161 ALA A CB   1 
ATOM 2232 H H    . ALA A 1 161 ? 93.972  96.904  109.927 1.00 49.60  ? 161 ALA A H    1 
ATOM 2233 H HA   . ALA A 1 161 ? 91.411  96.459  109.337 1.00 47.67  ? 161 ALA A HA   1 
ATOM 2234 H HB1  . ALA A 1 161 ? 92.040  94.220  109.139 1.00 48.92  ? 161 ALA A HB1  1 
ATOM 2235 H HB2  . ALA A 1 161 ? 93.023  95.143  108.297 1.00 47.90  ? 161 ALA A HB2  1 
ATOM 2236 H HB3  . ALA A 1 161 ? 93.481  94.575  109.708 1.00 48.84  ? 161 ALA A HB3  1 
ATOM 2237 N N    . VAL A 1 162 ? 92.351  96.023  112.313 1.00 55.17  ? 162 VAL A N    1 
ATOM 2238 C CA   . VAL A 1 162 ? 91.900  95.699  113.660 1.00 49.54  ? 162 VAL A CA   1 
ATOM 2239 C C    . VAL A 1 162 ? 91.599  96.940  114.489 1.00 49.09  ? 162 VAL A C    1 
ATOM 2240 O O    . VAL A 1 162 ? 90.788  96.855  115.424 1.00 50.78  ? 162 VAL A O    1 
ATOM 2241 C CB   . VAL A 1 162 ? 92.924  94.806  114.390 1.00 45.73  ? 162 VAL A CB   1 
ATOM 2242 C CG1  . VAL A 1 162 ? 92.492  94.563  115.830 1.00 49.81  ? 162 VAL A CG1  1 
ATOM 2243 C CG2  . VAL A 1 162 ? 93.090  93.485  113.652 1.00 51.03  ? 162 VAL A CG2  1 
ATOM 2244 H H    . VAL A 1 162 ? 93.128  96.389  112.283 1.00 51.53  ? 162 VAL A H    1 
ATOM 2245 H HA   . VAL A 1 162 ? 91.076  95.192  113.596 1.00 49.24  ? 162 VAL A HA   1 
ATOM 2246 H HB   . VAL A 1 162 ? 93.784  95.254  114.404 1.00 47.00  ? 162 VAL A HB   1 
ATOM 2247 H HG11 . VAL A 1 162 ? 92.666  95.361  116.354 1.00 50.47  ? 162 VAL A HG11 1 
ATOM 2248 H HG12 . VAL A 1 162 ? 91.545  94.357  115.845 1.00 47.10  ? 162 VAL A HG12 1 
ATOM 2249 H HG13 . VAL A 1 162 ? 92.999  93.819  116.192 1.00 51.26  ? 162 VAL A HG13 1 
ATOM 2250 H HG21 . VAL A 1 162 ? 92.541  93.498  112.853 1.00 50.47  ? 162 VAL A HG21 1 
ATOM 2251 H HG22 . VAL A 1 162 ? 94.023  93.373  113.411 1.00 49.51  ? 162 VAL A HG22 1 
ATOM 2252 H HG23 . VAL A 1 162 ? 92.810  92.760  114.232 1.00 52.02  ? 162 VAL A HG23 1 
ATOM 2253 N N    . CYS A 1 163 ? 92.210  98.080  114.184 1.00 47.70  ? 163 CYS A N    1 
ATOM 2254 C CA   . CYS A 1 163 ? 91.898  99.325  114.871 1.00 47.95  ? 163 CYS A CA   1 
ATOM 2255 C C    . CYS A 1 163 ? 90.642  99.993  114.330 1.00 47.64  ? 163 CYS A C    1 
ATOM 2256 O O    . CYS A 1 163 ? 90.206  101.004 114.890 1.00 47.62  ? 163 CYS A O    1 
ATOM 2257 C CB   . CYS A 1 163 ? 93.082  100.290 114.763 1.00 56.04  ? 163 CYS A CB   1 
ATOM 2258 S SG   . CYS A 1 163 ? 94.551  99.748  115.663 1.00 76.73  ? 163 CYS A SG   1 
ATOM 2259 H H    . CYS A 1 163 ? 92.815  98.157  113.577 1.00 50.01  ? 163 CYS A H    1 
ATOM 2260 H HA   . CYS A 1 163 ? 91.753  99.136  115.811 1.00 50.51  ? 163 CYS A HA   1 
ATOM 2261 H HB2  . CYS A 1 163 ? 93.324  100.383 113.829 1.00 53.62  ? 163 CYS A HB2  1 
ATOM 2262 H HB3  . CYS A 1 163 ? 92.816  101.151 115.122 1.00 55.20  ? 163 CYS A HB3  1 
ATOM 2263 H HG   . CYS A 1 163 ? 94.890  98.676  115.244 1.00 60.14  ? 163 CYS A HG   1 
ATOM 2264 N N    . GLY A 1 164 ? 90.055  99.460  113.260 1.00 49.99  ? 164 GLY A N    1 
ATOM 2265 C CA   . GLY A 1 164 ? 88.866  100.029 112.676 1.00 47.28  ? 164 GLY A CA   1 
ATOM 2266 C C    . GLY A 1 164 ? 87.621  99.708  113.477 1.00 45.36  ? 164 GLY A C    1 
ATOM 2267 O O    . GLY A 1 164 ? 86.935  100.600 113.984 1.00 52.95  ? 164 GLY A O    1 
ATOM 2268 H H    . GLY A 1 164 ? 90.338  98.757  112.854 1.00 49.96  ? 164 GLY A H    1 
ATOM 2269 H HA2  . GLY A 1 164 ? 88.960  100.993 112.627 1.00 47.15  ? 164 GLY A HA2  1 
ATOM 2270 H HA3  . GLY A 1 164 ? 88.751  99.685  111.777 1.00 48.44  ? 164 GLY A HA3  1 
ATOM 2271 N N    . PRO A 1 165 ? 87.299  98.419  113.606 1.00 37.92  ? 165 PRO A N    1 
ATOM 2272 C CA   . PRO A 1 165 ? 86.102  98.040  114.370 1.00 47.54  ? 165 PRO A CA   1 
ATOM 2273 C C    . PRO A 1 165 ? 86.298  98.180  115.871 1.00 53.01  ? 165 PRO A C    1 
ATOM 2274 O O    . PRO A 1 165 ? 85.373  98.580  116.586 1.00 56.35  ? 165 PRO A O    1 
ATOM 2275 C CB   . PRO A 1 165 ? 85.864  96.576  113.969 1.00 44.05  ? 165 PRO A CB   1 
ATOM 2276 C CG   . PRO A 1 165 ? 86.913  96.233  112.947 1.00 48.85  ? 165 PRO A CG   1 
ATOM 2277 C CD   . PRO A 1 165 ? 87.992  97.251  113.044 1.00 39.63  ? 165 PRO A CD   1 
ATOM 2278 H HA   . PRO A 1 165 ? 85.342  98.574  114.092 1.00 47.66  ? 165 PRO A HA   1 
ATOM 2279 H HB2  . PRO A 1 165 ? 85.953  96.008  114.751 1.00 45.47  ? 165 PRO A HB2  1 
ATOM 2280 H HB3  . PRO A 1 165 ? 84.977  96.487  113.587 1.00 44.29  ? 165 PRO A HB3  1 
ATOM 2281 H HG2  . PRO A 1 165 ? 87.266  95.350  113.137 1.00 47.83  ? 165 PRO A HG2  1 
ATOM 2282 H HG3  . PRO A 1 165 ? 86.514  96.251  112.063 1.00 49.52  ? 165 PRO A HG3  1 
ATOM 2283 H HD2  . PRO A 1 165 ? 88.693  96.950  113.643 1.00 44.44  ? 165 PRO A HD2  1 
ATOM 2284 H HD3  . PRO A 1 165 ? 88.339  97.451  112.161 1.00 44.11  ? 165 PRO A HD3  1 
ATOM 2285 N N    . ALA A 1 166 ? 87.499  97.864  116.360 1.00 52.51  ? 166 ALA A N    1 
ATOM 2286 C CA   . ALA A 1 166 ? 87.751  97.936  117.796 1.00 53.20  ? 166 ALA A CA   1 
ATOM 2287 C C    . ALA A 1 166 ? 87.508  99.345  118.322 1.00 50.65  ? 166 ALA A C    1 
ATOM 2288 O O    . ALA A 1 166 ? 86.782  99.538  119.305 1.00 51.07  ? 166 ALA A O    1 
ATOM 2289 C CB   . ALA A 1 166 ? 89.180  97.487  118.098 1.00 51.77  ? 166 ALA A CB   1 
ATOM 2290 H H    . ALA A 1 166 ? 88.171  97.609  115.889 1.00 50.07  ? 166 ALA A H    1 
ATOM 2291 H HA   . ALA A 1 166 ? 87.143  97.335  118.254 1.00 52.45  ? 166 ALA A HA   1 
ATOM 2292 H HB1  . ALA A 1 166 ? 89.800  98.070  117.633 1.00 51.37  ? 166 ALA A HB1  1 
ATOM 2293 H HB2  . ALA A 1 166 ? 89.331  97.539  119.055 1.00 51.51  ? 166 ALA A HB2  1 
ATOM 2294 H HB3  . ALA A 1 166 ? 89.294  96.573  117.795 1.00 50.61  ? 166 ALA A HB3  1 
ATOM 2295 N N    . SER A 1 167 ? 88.093  100.348 117.665 1.00 47.66  ? 167 SER A N    1 
ATOM 2296 C CA   . SER A 1 167 ? 87.876  101.728 118.079 1.00 49.81  ? 167 SER A CA   1 
ATOM 2297 C C    . SER A 1 167 ? 86.419  102.142 117.939 1.00 54.28  ? 167 SER A C    1 
ATOM 2298 O O    . SER A 1 167 ? 86.000  103.115 118.574 1.00 55.83  ? 167 SER A O    1 
ATOM 2299 C CB   . SER A 1 167 ? 88.768  102.666 117.264 1.00 49.14  ? 167 SER A CB   1 
ATOM 2300 O OG   . SER A 1 167 ? 88.068  103.208 116.158 1.00 47.84  ? 167 SER A OG   1 
ATOM 2301 H H    . SER A 1 167 ? 88.611  100.254 116.985 1.00 48.91  ? 167 SER A H    1 
ATOM 2302 H HA   . SER A 1 167 ? 88.122  101.817 119.012 1.00 49.79  ? 167 SER A HA   1 
ATOM 2303 H HB2  . SER A 1 167 ? 89.064  103.392 117.835 1.00 50.07  ? 167 SER A HB2  1 
ATOM 2304 H HB3  . SER A 1 167 ? 89.535  102.169 116.939 1.00 49.45  ? 167 SER A HB3  1 
ATOM 2305 H HG   . SER A 1 167 ? 87.559  103.825 116.414 1.00 47.89  ? 167 SER A HG   1 
ATOM 2306 N N    . ASP A 1 168 ? 85.639  101.428 117.127 1.00 53.64  ? 168 ASP A N    1 
ATOM 2307 C CA   . ASP A 1 168 ? 84.219  101.717 116.992 1.00 54.92  ? 168 ASP A CA   1 
ATOM 2308 C C    . ASP A 1 168 ? 83.377  101.063 118.079 1.00 57.53  ? 168 ASP A C    1 
ATOM 2309 O O    . ASP A 1 168 ? 82.165  101.301 118.123 1.00 62.06  ? 168 ASP A O    1 
ATOM 2310 C CB   . ASP A 1 168 ? 83.718  101.262 115.619 1.00 56.06  ? 168 ASP A CB   1 
ATOM 2311 C CG   . ASP A 1 168 ? 84.137  102.201 114.506 1.00 59.17  ? 168 ASP A CG   1 
ATOM 2312 O OD1  . ASP A 1 168 ? 85.085  102.987 114.715 1.00 55.49  ? 168 ASP A OD1  1 
ATOM 2313 O OD2  . ASP A 1 168 ? 83.519  102.154 113.422 1.00 61.48  ? 168 ASP A OD2  1 
ATOM 2314 H H    . ASP A 1 168 ? 85.912  100.771 116.643 1.00 52.92  ? 168 ASP A H    1 
ATOM 2315 H HA   . ASP A 1 168 ? 84.087  102.676 117.052 1.00 54.34  ? 168 ASP A HA   1 
ATOM 2316 H HB2  . ASP A 1 168 ? 84.081  100.384 115.424 1.00 55.31  ? 168 ASP A HB2  1 
ATOM 2317 H HB3  . ASP A 1 168 ? 82.749  101.225 115.631 1.00 56.02  ? 168 ASP A HB3  1 
ATOM 2318 N N    . ARG A 1 169 ? 83.978  100.250 118.946 1.00 55.66  ? 169 ARG A N    1 
ATOM 2319 C CA   . ARG A 1 169 ? 83.258  99.583  120.025 1.00 60.44  ? 169 ARG A CA   1 
ATOM 2320 C C    . ARG A 1 169 ? 83.705  100.028 121.409 1.00 66.06  ? 169 ARG A C    1 
ATOM 2321 O O    . ARG A 1 169 ? 82.862  100.251 122.280 1.00 65.50  ? 169 ARG A O    1 
ATOM 2322 C CB   . ARG A 1 169 ? 83.424  98.063  119.908 1.00 60.11  ? 169 ARG A CB   1 
ATOM 2323 C CG   . ARG A 1 169 ? 82.933  97.295  121.123 1.00 67.35  ? 169 ARG A CG   1 
ATOM 2324 C CD   . ARG A 1 169 ? 82.453  95.900  120.758 1.00 76.91  ? 169 ARG A CD   1 
ATOM 2325 N NE   . ARG A 1 169 ? 81.262  95.919  119.918 1.00 84.02  ? 169 ARG A NE   1 
ATOM 2326 C CZ   . ARG A 1 169 ? 80.045  96.227  120.346 1.00 86.00  ? 169 ARG A CZ   1 
ATOM 2327 N NH1  . ARG A 1 169 ? 79.818  96.563  121.606 1.00 85.37  ? 169 ARG A NH1  1 
ATOM 2328 N NH2  . ARG A 1 169 ? 79.030  96.198  119.488 1.00 86.56  ? 169 ARG A NH2  1 
ATOM 2329 H H    . ARG A 1 169 ? 84.817  100.066 118.929 1.00 55.77  ? 169 ARG A H    1 
ATOM 2330 H HA   . ARG A 1 169 ? 82.313  99.782  119.943 1.00 62.29  ? 169 ARG A HA   1 
ATOM 2331 H HB2  . ARG A 1 169 ? 82.924  97.754  119.137 1.00 63.13  ? 169 ARG A HB2  1 
ATOM 2332 H HB3  . ARG A 1 169 ? 84.366  97.862  119.790 1.00 58.86  ? 169 ARG A HB3  1 
ATOM 2333 H HG2  . ARG A 1 169 ? 83.655  97.207  121.759 1.00 67.18  ? 169 ARG A HG2  1 
ATOM 2334 H HG3  . ARG A 1 169 ? 82.191  97.773  121.525 1.00 69.80  ? 169 ARG A HG3  1 
ATOM 2335 H HD2  . ARG A 1 169 ? 83.156  95.441  120.272 1.00 76.62  ? 169 ARG A HD2  1 
ATOM 2336 H HD3  . ARG A 1 169 ? 82.240  95.417  121.571 1.00 76.46  ? 169 ARG A HD3  1 
ATOM 2337 H HE   . ARG A 1 169 ? 81.346  95.671  119.100 1.00 82.16  ? 169 ARG A HE   1 
ATOM 2338 H HH11 . ARG A 1 169 ? 80.465  96.586  122.171 1.00 81.84  ? 169 ARG A HH11 1 
ATOM 2339 H HH12 . ARG A 1 169 ? 79.020  96.759  121.860 1.00 84.62  ? 169 ARG A HH12 1 
ATOM 2340 H HH21 . ARG A 1 169 ? 79.167  95.980  118.668 1.00 84.49  ? 169 ARG A HH21 1 
ATOM 2341 H HH22 . ARG A 1 169 ? 78.236  96.396  119.754 1.00 85.99  ? 169 ARG A HH22 1 
ATOM 2342 N N    . PHE A 1 170 ? 85.012  100.161 121.638 1.00 66.25  ? 170 PHE A N    1 
ATOM 2343 C CA   . PHE A 1 170 ? 85.527  100.603 122.930 1.00 54.01  ? 170 PHE A CA   1 
ATOM 2344 C C    . PHE A 1 170 ? 85.648  102.116 123.038 1.00 55.68  ? 170 PHE A C    1 
ATOM 2345 O O    . PHE A 1 170 ? 85.461  102.665 124.130 1.00 60.20  ? 170 PHE A O    1 
ATOM 2346 C CB   . PHE A 1 170 ? 86.898  99.973  123.199 1.00 54.53  ? 170 PHE A CB   1 
ATOM 2347 C CG   . PHE A 1 170 ? 86.914  98.472  123.106 1.00 60.74  ? 170 PHE A CG   1 
ATOM 2348 C CD1  . PHE A 1 170 ? 85.754  97.735  123.273 1.00 64.85  ? 170 PHE A CD1  1 
ATOM 2349 C CD2  . PHE A 1 170 ? 88.093  97.797  122.839 1.00 55.59  ? 170 PHE A CD2  1 
ATOM 2350 C CE1  . PHE A 1 170 ? 85.771  96.357  123.186 1.00 66.89  ? 170 PHE A CE1  1 
ATOM 2351 C CE2  . PHE A 1 170 ? 88.114  96.419  122.749 1.00 54.29  ? 170 PHE A CE2  1 
ATOM 2352 C CZ   . PHE A 1 170 ? 86.951  95.699  122.922 1.00 64.06  ? 170 PHE A CZ   1 
ATOM 2353 H H    . PHE A 1 170 ? 85.624  99.999  121.056 1.00 61.09  ? 170 PHE A H    1 
ATOM 2354 H HA   . PHE A 1 170 ? 84.920  100.309 123.627 1.00 56.93  ? 170 PHE A HA   1 
ATOM 2355 H HB2  . PHE A 1 170 ? 87.529  100.315 122.547 1.00 56.33  ? 170 PHE A HB2  1 
ATOM 2356 H HB3  . PHE A 1 170 ? 87.183  100.218 124.093 1.00 57.08  ? 170 PHE A HB3  1 
ATOM 2357 H HD1  . PHE A 1 170 ? 84.952  98.171  123.453 1.00 63.35  ? 170 PHE A HD1  1 
ATOM 2358 H HD2  . PHE A 1 170 ? 88.880  98.278  122.722 1.00 56.60  ? 170 PHE A HD2  1 
ATOM 2359 H HE1  . PHE A 1 170 ? 84.985  95.873  123.303 1.00 65.06  ? 170 PHE A HE1  1 
ATOM 2360 H HE2  . PHE A 1 170 ? 88.912  95.977  122.571 1.00 55.54  ? 170 PHE A HE2  1 
ATOM 2361 H HZ   . PHE A 1 170 ? 86.963  94.771  122.862 1.00 63.19  ? 170 PHE A HZ   1 
ATOM 2362 N N    . GLY A 1 171 ? 85.961  102.802 121.942 1.00 58.23  ? 171 GLY A N    1 
ATOM 2363 C CA   . GLY A 1 171 ? 86.113  104.244 121.972 1.00 54.13  ? 171 GLY A CA   1 
ATOM 2364 C C    . GLY A 1 171 ? 87.323  104.720 121.198 1.00 53.60  ? 171 GLY A C    1 
ATOM 2365 O O    . GLY A 1 171 ? 88.053  103.911 120.618 1.00 51.41  ? 171 GLY A O    1 
ATOM 2366 H H    . GLY A 1 171 ? 86.088  102.451 121.167 1.00 57.03  ? 171 GLY A H    1 
ATOM 2367 H HA2  . GLY A 1 171 ? 85.323  104.659 121.593 1.00 54.01  ? 171 GLY A HA2  1 
ATOM 2368 H HA3  . GLY A 1 171 ? 86.205  104.542 122.890 1.00 54.33  ? 171 GLY A HA3  1 
ATOM 2369 N N    . ARG A 1 172 ? 87.548  106.033 121.180 1.00 53.85  ? 172 ARG A N    1 
ATOM 2370 C CA   . ARG A 1 172 ? 88.696  106.604 120.485 1.00 49.18  ? 172 ARG A CA   1 
ATOM 2371 C C    . ARG A 1 172 ? 89.869  106.837 121.433 1.00 55.06  ? 172 ARG A C    1 
ATOM 2372 O O    . ARG A 1 172 ? 91.001  106.437 121.141 1.00 59.76  ? 172 ARG A O    1 
ATOM 2373 C CB   . ARG A 1 172 ? 88.310  107.926 119.807 1.00 52.69  ? 172 ARG A CB   1 
ATOM 2374 C CG   . ARG A 1 172 ? 86.881  108.001 119.270 1.00 58.61  ? 172 ARG A CG   1 
ATOM 2375 C CD   . ARG A 1 172 ? 86.653  107.067 118.094 1.00 54.39  ? 172 ARG A CD   1 
ATOM 2376 N NE   . ARG A 1 172 ? 85.246  107.010 117.716 1.00 56.61  ? 172 ARG A NE   1 
ATOM 2377 C CZ   . ARG A 1 172 ? 84.785  106.423 116.619 1.00 65.00  ? 172 ARG A CZ   1 
ATOM 2378 N NH1  . ARG A 1 172 ? 85.595  105.820 115.764 1.00 69.59  ? 172 ARG A NH1  1 
ATOM 2379 N NH2  . ARG A 1 172 ? 83.478  106.442 116.374 1.00 65.84  ? 172 ARG A NH2  1 
ATOM 2380 H H    . ARG A 1 172 ? 87.048  106.616 121.567 1.00 53.92  ? 172 ARG A H    1 
ATOM 2381 H HA   . ARG A 1 172 ? 88.984  105.987 119.795 1.00 51.44  ? 172 ARG A HA   1 
ATOM 2382 H HB2  . ARG A 1 172 ? 88.416  108.643 120.452 1.00 53.95  ? 172 ARG A HB2  1 
ATOM 2383 H HB3  . ARG A 1 172 ? 88.909  108.072 119.059 1.00 52.59  ? 172 ARG A HB3  1 
ATOM 2384 H HG2  . ARG A 1 172 ? 86.254  107.765 119.972 1.00 57.97  ? 172 ARG A HG2  1 
ATOM 2385 H HG3  . ARG A 1 172 ? 86.709  108.906 118.967 1.00 58.76  ? 172 ARG A HG3  1 
ATOM 2386 H HD2  . ARG A 1 172 ? 87.160  107.385 117.331 1.00 54.48  ? 172 ARG A HD2  1 
ATOM 2387 H HD3  . ARG A 1 172 ? 86.938  106.172 118.337 1.00 55.66  ? 172 ARG A HD3  1 
ATOM 2388 H HE   . ARG A 1 172 ? 84.671  107.348 118.259 1.00 57.13  ? 172 ARG A HE   1 
ATOM 2389 H HH11 . ARG A 1 172 ? 86.442  105.801 115.911 1.00 63.09  ? 172 ARG A HH11 1 
ATOM 2390 H HH12 . ARG A 1 172 ? 85.273  105.446 115.060 1.00 64.82  ? 172 ARG A HH12 1 
ATOM 2391 H HH21 . ARG A 1 172 ? 82.943  106.831 116.923 1.00 64.23  ? 172 ARG A HH21 1 
ATOM 2392 H HH22 . ARG A 1 172 ? 83.168  106.064 115.666 1.00 64.44  ? 172 ARG A HH22 1 
ATOM 2393 N N    . ARG A 1 173 ? 89.608  107.484 122.571 1.00 49.58  ? 173 ARG A N    1 
ATOM 2394 C CA   . ARG A 1 173 ? 90.679  107.811 123.505 1.00 47.33  ? 173 ARG A CA   1 
ATOM 2395 C C    . ARG A 1 173 ? 91.329  106.557 124.072 1.00 53.57  ? 173 ARG A C    1 
ATOM 2396 O O    . ARG A 1 173 ? 92.551  106.510 124.251 1.00 55.11  ? 173 ARG A O    1 
ATOM 2397 C CB   . ARG A 1 173 ? 90.135  108.684 124.632 1.00 53.22  ? 173 ARG A CB   1 
ATOM 2398 C CG   . ARG A 1 173 ? 91.073  108.810 125.822 1.00 56.02  ? 173 ARG A CG   1 
ATOM 2399 C CD   . ARG A 1 173 ? 90.889  110.132 126.547 1.00 58.10  ? 173 ARG A CD   1 
ATOM 2400 N NE   . ARG A 1 173 ? 90.106  109.993 127.769 1.00 54.25  ? 173 ARG A NE   1 
ATOM 2401 C CZ   . ARG A 1 173 ? 90.499  109.322 128.843 1.00 66.83  ? 173 ARG A CZ   1 
ATOM 2402 N NH1  . ARG A 1 173 ? 91.666  108.699 128.882 1.00 74.87  ? 173 ARG A NH1  1 
ATOM 2403 N NH2  . ARG A 1 173 ? 89.703  109.277 129.907 1.00 70.75  ? 173 ARG A NH2  1 
ATOM 2404 H H    . ARG A 1 173 ? 88.826  107.741 122.821 1.00 50.53  ? 173 ARG A H    1 
ATOM 2405 H HA   . ARG A 1 173 ? 91.363  108.317 123.037 1.00 49.47  ? 173 ARG A HA   1 
ATOM 2406 H HB2  . ARG A 1 173 ? 89.971  109.572 124.278 1.00 54.95  ? 173 ARG A HB2  1 
ATOM 2407 H HB3  . ARG A 1 173 ? 89.304  108.300 124.951 1.00 52.25  ? 173 ARG A HB3  1 
ATOM 2408 H HG2  . ARG A 1 173 ? 90.893  108.090 126.446 1.00 56.09  ? 173 ARG A HG2  1 
ATOM 2409 H HG3  . ARG A 1 173 ? 91.991  108.763 125.512 1.00 56.20  ? 173 ARG A HG3  1 
ATOM 2410 H HD2  . ARG A 1 173 ? 91.762  110.480 126.791 1.00 58.39  ? 173 ARG A HD2  1 
ATOM 2411 H HD3  . ARG A 1 173 ? 90.433  110.763 125.970 1.00 58.44  ? 173 ARG A HD3  1 
ATOM 2412 H HE   . ARG A 1 173 ? 89.318  110.337 127.780 1.00 55.62  ? 173 ARG A HE   1 
ATOM 2413 H HH11 . ARG A 1 173 ? 92.191  108.721 128.201 1.00 69.44  ? 173 ARG A HH11 1 
ATOM 2414 H HH12 . ARG A 1 173 ? 91.900  108.271 129.590 1.00 73.10  ? 173 ARG A HH12 1 
ATOM 2415 H HH21 . ARG A 1 173 ? 88.943  109.679 129.892 1.00 66.30  ? 173 ARG A HH21 1 
ATOM 2416 H HH22 . ARG A 1 173 ? 89.947  108.845 130.609 1.00 71.46  ? 173 ARG A HH22 1 
ATOM 2417 N N    . LEU A 1 174 ? 90.528  105.537 124.383 1.00 50.13  ? 174 LEU A N    1 
ATOM 2418 C CA   . LEU A 1 174 ? 91.086  104.303 124.926 1.00 41.43  ? 174 LEU A CA   1 
ATOM 2419 C C    . LEU A 1 174 ? 92.070  103.677 123.947 1.00 42.08  ? 174 LEU A C    1 
ATOM 2420 O O    . LEU A 1 174 ? 93.189  103.305 124.321 1.00 50.53  ? 174 LEU A O    1 
ATOM 2421 C CB   . LEU A 1 174 ? 89.957  103.326 125.255 1.00 41.00  ? 174 LEU A CB   1 
ATOM 2422 C CG   . LEU A 1 174 ? 90.280  102.240 126.282 1.00 50.78  ? 174 LEU A CG   1 
ATOM 2423 C CD1  . LEU A 1 174 ? 89.057  101.932 127.130 1.00 56.66  ? 174 LEU A CD1  1 
ATOM 2424 C CD2  . LEU A 1 174 ? 90.785  100.985 125.589 1.00 52.28  ? 174 LEU A CD2  1 
ATOM 2425 H H    . LEU A 1 174 ? 89.673  105.535 124.291 1.00 50.13  ? 174 LEU A H    1 
ATOM 2426 H HA   . LEU A 1 174 ? 91.562  104.503 125.747 1.00 47.01  ? 174 LEU A HA   1 
ATOM 2427 H HB2  . LEU A 1 174 ? 89.206  103.834 125.600 1.00 45.02  ? 174 LEU A HB2  1 
ATOM 2428 H HB3  . LEU A 1 174 ? 89.693  102.879 124.436 1.00 46.72  ? 174 LEU A HB3  1 
ATOM 2429 H HG   . LEU A 1 174 ? 90.980  102.560 126.872 1.00 50.11  ? 174 LEU A HG   1 
ATOM 2430 H HD11 . LEU A 1 174 ? 88.334  101.648 126.548 1.00 55.11  ? 174 LEU A HD11 1 
ATOM 2431 H HD12 . LEU A 1 174 ? 89.277  101.222 127.754 1.00 53.72  ? 174 LEU A HD12 1 
ATOM 2432 H HD13 . LEU A 1 174 ? 88.798  102.731 127.614 1.00 53.91  ? 174 LEU A HD13 1 
ATOM 2433 H HD21 . LEU A 1 174 ? 91.591  101.199 125.095 1.00 48.92  ? 174 LEU A HD21 1 
ATOM 2434 H HD22 . LEU A 1 174 ? 90.976  100.310 126.259 1.00 51.53  ? 174 LEU A HD22 1 
ATOM 2435 H HD23 . LEU A 1 174 ? 90.100  100.663 124.982 1.00 53.19  ? 174 LEU A HD23 1 
ATOM 2436 N N    . VAL A 1 175 ? 91.667  103.562 122.680 1.00 38.25  ? 175 VAL A N    1 
ATOM 2437 C CA   . VAL A 1 175 ? 92.543  102.975 121.671 1.00 39.17  ? 175 VAL A CA   1 
ATOM 2438 C C    . VAL A 1 175 ? 93.781  103.837 121.476 1.00 44.15  ? 175 VAL A C    1 
ATOM 2439 O O    . VAL A 1 175 ? 94.892  103.321 121.320 1.00 48.14  ? 175 VAL A O    1 
ATOM 2440 C CB   . VAL A 1 175 ? 91.780  102.776 120.350 1.00 40.85  ? 175 VAL A CB   1 
ATOM 2441 C CG1  . VAL A 1 175 ? 92.740  102.346 119.249 1.00 39.66  ? 175 VAL A CG1  1 
ATOM 2442 C CG2  . VAL A 1 175 ? 90.666  101.755 120.536 1.00 49.67  ? 175 VAL A CG2  1 
ATOM 2443 H H    . VAL A 1 175 ? 90.899  103.813 122.384 1.00 43.72  ? 175 VAL A H    1 
ATOM 2444 H HA   . VAL A 1 175 ? 92.835  102.103 121.980 1.00 41.83  ? 175 VAL A HA   1 
ATOM 2445 H HB   . VAL A 1 175 ? 91.377  103.618 120.086 1.00 44.45  ? 175 VAL A HB   1 
ATOM 2446 H HG11 . VAL A 1 175 ? 93.392  101.731 119.619 1.00 41.09  ? 175 VAL A HG11 1 
ATOM 2447 H HG12 . VAL A 1 175 ? 92.240  101.912 118.539 1.00 42.86  ? 175 VAL A HG12 1 
ATOM 2448 H HG13 . VAL A 1 175 ? 93.187  103.132 118.897 1.00 40.32  ? 175 VAL A HG13 1 
ATOM 2449 H HG21 . VAL A 1 175 ? 90.732  101.376 121.427 1.00 47.59  ? 175 VAL A HG21 1 
ATOM 2450 H HG22 . VAL A 1 175 ? 89.812  102.202 120.432 1.00 49.48  ? 175 VAL A HG22 1 
ATOM 2451 H HG23 . VAL A 1 175 ? 90.756  101.054 119.873 1.00 48.06  ? 175 VAL A HG23 1 
ATOM 2452 N N    . LEU A 1 176 ? 93.614  105.160 121.467 1.00 42.87  ? 176 LEU A N    1 
ATOM 2453 C CA   . LEU A 1 176 ? 94.764  106.041 121.287 1.00 44.94  ? 176 LEU A CA   1 
ATOM 2454 C C    . LEU A 1 176 ? 95.778  105.853 122.411 1.00 45.75  ? 176 LEU A C    1 
ATOM 2455 O O    . LEU A 1 176 ? 96.985  105.734 122.166 1.00 49.43  ? 176 LEU A O    1 
ATOM 2456 C CB   . LEU A 1 176 ? 94.295  107.495 121.223 1.00 42.29  ? 176 LEU A CB   1 
ATOM 2457 C CG   . LEU A 1 176 ? 95.362  108.554 120.939 1.00 46.52  ? 176 LEU A CG   1 
ATOM 2458 C CD1  . LEU A 1 176 ? 96.074  108.268 119.627 1.00 50.05  ? 176 LEU A CD1  1 
ATOM 2459 C CD2  . LEU A 1 176 ? 94.745  109.943 120.925 1.00 56.73  ? 176 LEU A CD2  1 
ATOM 2460 H H    . LEU A 1 176 ? 92.861  105.564 121.561 1.00 45.27  ? 176 LEU A H    1 
ATOM 2461 H HA   . LEU A 1 176 ? 95.198  105.824 120.448 1.00 45.62  ? 176 LEU A HA   1 
ATOM 2462 H HB2  . LEU A 1 176 ? 93.627  107.566 120.523 1.00 45.77  ? 176 LEU A HB2  1 
ATOM 2463 H HB3  . LEU A 1 176 ? 93.889  107.719 122.075 1.00 45.18  ? 176 LEU A HB3  1 
ATOM 2464 H HG   . LEU A 1 176 ? 96.023  108.530 121.648 1.00 45.14  ? 176 LEU A HG   1 
ATOM 2465 H HD11 . LEU A 1 176 ? 95.412  108.160 118.926 1.00 50.41  ? 176 LEU A HD11 1 
ATOM 2466 H HD12 . LEU A 1 176 ? 96.660  109.012 119.418 1.00 50.49  ? 176 LEU A HD12 1 
ATOM 2467 H HD13 . LEU A 1 176 ? 96.593  107.455 119.721 1.00 47.25  ? 176 LEU A HD13 1 
ATOM 2468 H HD21 . LEU A 1 176 ? 94.323  110.108 121.783 1.00 55.32  ? 176 LEU A HD21 1 
ATOM 2469 H HD22 . LEU A 1 176 ? 95.443  110.597 120.768 1.00 55.20  ? 176 LEU A HD22 1 
ATOM 2470 H HD23 . LEU A 1 176 ? 94.083  109.987 120.217 1.00 53.91  ? 176 LEU A HD23 1 
ATOM 2471 N N    . THR A 1 177 ? 95.299  105.820 123.656 1.00 38.22  ? 177 THR A N    1 
ATOM 2472 C CA   . THR A 1 177 ? 96.193  105.649 124.797 1.00 34.56  ? 177 THR A CA   1 
ATOM 2473 C C    . THR A 1 177 ? 96.880  104.288 124.757 1.00 38.52  ? 177 THR A C    1 
ATOM 2474 O O    . THR A 1 177 ? 98.093  104.183 124.995 1.00 42.46  ? 177 THR A O    1 
ATOM 2475 C CB   . THR A 1 177 ? 95.404  105.820 126.095 1.00 36.46  ? 177 THR A CB   1 
ATOM 2476 O OG1  . THR A 1 177 ? 95.009  107.190 126.237 1.00 40.94  ? 177 THR A OG1  1 
ATOM 2477 C CG2  . THR A 1 177 ? 96.238  105.422 127.297 1.00 40.63  ? 177 THR A CG2  1 
ATOM 2478 H H    . THR A 1 177 ? 94.468  105.893 123.864 1.00 42.75  ? 177 THR A H    1 
ATOM 2479 H HA   . THR A 1 177 ? 96.879  106.334 124.768 1.00 38.14  ? 177 THR A HA   1 
ATOM 2480 H HB   . THR A 1 177 ? 94.614  105.257 126.070 1.00 39.82  ? 177 THR A HB   1 
ATOM 2481 H HG1  . THR A 1 177 ? 95.688  107.681 126.286 1.00 42.60  ? 177 THR A HG1  1 
ATOM 2482 H HG21 . THR A 1 177 ? 97.109  105.840 127.238 1.00 41.14  ? 177 THR A HG21 1 
ATOM 2483 H HG22 . THR A 1 177 ? 95.802  105.718 128.112 1.00 38.93  ? 177 THR A HG22 1 
ATOM 2484 H HG23 . THR A 1 177 ? 96.347  104.459 127.333 1.00 39.70  ? 177 THR A HG23 1 
ATOM 2485 N N    . TRP A 1 178 ? 96.121  103.232 124.451 1.00 41.61  ? 178 TRP A N    1 
ATOM 2486 C CA   . TRP A 1 178 ? 96.715  101.902 124.386 1.00 36.75  ? 178 TRP A CA   1 
ATOM 2487 C C    . TRP A 1 178 ? 97.766  101.828 123.288 1.00 38.16  ? 178 TRP A C    1 
ATOM 2488 O O    . TRP A 1 178 ? 98.809  101.188 123.459 1.00 41.10  ? 178 TRP A O    1 
ATOM 2489 C CB   . TRP A 1 178 ? 95.628  100.852 124.160 1.00 37.31  ? 178 TRP A CB   1 
ATOM 2490 C CG   . TRP A 1 178 ? 96.168  99.520  123.752 1.00 45.38  ? 178 TRP A CG   1 
ATOM 2491 C CD1  . TRP A 1 178 ? 96.442  99.098  122.485 1.00 44.68  ? 178 TRP A CD1  1 
ATOM 2492 C CD2  . TRP A 1 178 ? 96.503  98.431  124.619 1.00 55.64  ? 178 TRP A CD2  1 
ATOM 2493 N NE1  . TRP A 1 178 ? 96.928  97.814  122.508 1.00 54.18  ? 178 TRP A NE1  1 
ATOM 2494 C CE2  . TRP A 1 178 ? 96.975  97.381  123.807 1.00 59.70  ? 178 TRP A CE2  1 
ATOM 2495 C CE3  . TRP A 1 178 ? 96.450  98.242  126.003 1.00 56.76  ? 178 TRP A CE3  1 
ATOM 2496 C CZ2  . TRP A 1 178 ? 97.390  96.159  124.333 1.00 66.74  ? 178 TRP A CZ2  1 
ATOM 2497 C CZ3  . TRP A 1 178 ? 96.863  97.028  126.524 1.00 60.94  ? 178 TRP A CZ3  1 
ATOM 2498 C CH2  . TRP A 1 178 ? 97.326  96.003  125.690 1.00 66.10  ? 178 TRP A CH2  1 
ATOM 2499 H H    . TRP A 1 178 ? 95.279  103.260 124.281 1.00 42.30  ? 178 TRP A H    1 
ATOM 2500 H HA   . TRP A 1 178 ? 97.149  101.708 125.232 1.00 39.91  ? 178 TRP A HA   1 
ATOM 2501 H HB2  . TRP A 1 178 ? 95.131  100.732 124.985 1.00 42.32  ? 178 TRP A HB2  1 
ATOM 2502 H HB3  . TRP A 1 178 ? 95.034  101.161 123.459 1.00 41.83  ? 178 TRP A HB3  1 
ATOM 2503 H HD1  . TRP A 1 178 ? 96.320  99.607  121.716 1.00 46.26  ? 178 TRP A HD1  1 
ATOM 2504 H HE1  . TRP A 1 178 ? 97.164  97.356  121.820 1.00 54.55  ? 178 TRP A HE1  1 
ATOM 2505 H HE3  . TRP A 1 178 ? 96.143  98.918  126.563 1.00 54.98  ? 178 TRP A HE3  1 
ATOM 2506 H HZ2  . TRP A 1 178 ? 97.699  95.477  123.783 1.00 63.49  ? 178 TRP A HZ2  1 
ATOM 2507 H HZ3  . TRP A 1 178 ? 96.832  96.891  127.443 1.00 61.60  ? 178 TRP A HZ3  1 
ATOM 2508 H HH2  . TRP A 1 178 ? 97.598  95.198  126.068 1.00 64.06  ? 178 TRP A HH2  1 
ATOM 2509 N N    . SER A 1 179 ? 97.505  102.467 122.147 1.00 36.44  ? 179 SER A N    1 
ATOM 2510 C CA   . SER A 1 179 ? 98.468  102.449 121.054 1.00 38.21  ? 179 SER A CA   1 
ATOM 2511 C C    . SER A 1 179 ? 99.719  103.241 121.411 1.00 42.17  ? 179 SER A C    1 
ATOM 2512 O O    . SER A 1 179 ? 100.829 102.852 121.035 1.00 46.03  ? 179 SER A O    1 
ATOM 2513 C CB   . SER A 1 179 ? 97.824  102.997 119.783 1.00 42.94  ? 179 SER A CB   1 
ATOM 2514 O OG   . SER A 1 179 ? 96.889  102.076 119.250 1.00 53.17  ? 179 SER A OG   1 
ATOM 2515 H H    . SER A 1 179 ? 96.786  102.911 121.985 1.00 40.29  ? 179 SER A H    1 
ATOM 2516 H HA   . SER A 1 179 ? 98.733  101.532 120.883 1.00 41.38  ? 179 SER A HA   1 
ATOM 2517 H HB2  . SER A 1 179 ? 97.372  103.831 119.987 1.00 42.80  ? 179 SER A HB2  1 
ATOM 2518 H HB3  . SER A 1 179 ? 98.519  103.144 119.125 1.00 42.26  ? 179 SER A HB3  1 
ATOM 2519 H HG   . SER A 1 179 ? 96.268  101.946 119.801 1.00 47.82  ? 179 SER A HG   1 
ATOM 2520 N N    . TYR A 1 180 ? 99.567  104.353 122.133 1.00 46.33  ? 180 TYR A N    1 
ATOM 2521 C CA   . TYR A 1 180 ? 100.742 105.065 122.627 1.00 41.67  ? 180 TYR A CA   1 
ATOM 2522 C C    . TYR A 1 180 ? 101.582 104.161 123.522 1.00 41.77  ? 180 TYR A C    1 
ATOM 2523 O O    . TYR A 1 180 ? 102.811 104.088 123.382 1.00 42.75  ? 180 TYR A O    1 
ATOM 2524 C CB   . TYR A 1 180 ? 100.320 106.322 123.395 1.00 41.38  ? 180 TYR A CB   1 
ATOM 2525 C CG   . TYR A 1 180 ? 99.993  107.539 122.548 1.00 49.86  ? 180 TYR A CG   1 
ATOM 2526 C CD1  . TYR A 1 180 ? 100.166 107.533 121.169 1.00 49.12  ? 180 TYR A CD1  1 
ATOM 2527 C CD2  . TYR A 1 180 ? 99.517  108.702 123.138 1.00 49.84  ? 180 TYR A CD2  1 
ATOM 2528 C CE1  . TYR A 1 180 ? 99.869  108.646 120.408 1.00 52.41  ? 180 TYR A CE1  1 
ATOM 2529 C CE2  . TYR A 1 180 ? 99.218  109.818 122.383 1.00 46.89  ? 180 TYR A CE2  1 
ATOM 2530 C CZ   . TYR A 1 180 ? 99.396  109.784 121.019 1.00 49.55  ? 180 TYR A CZ   1 
ATOM 2531 O OH   . TYR A 1 180 ? 99.101  110.892 120.261 1.00 56.37  ? 180 TYR A OH   1 
ATOM 2532 H H    . TYR A 1 180 ? 98.813  104.707 122.345 1.00 44.14  ? 180 TYR A H    1 
ATOM 2533 H HA   . TYR A 1 180 ? 101.303 105.320 121.880 1.00 42.35  ? 180 TYR A HA   1 
ATOM 2534 H HB2  . TYR A 1 180 ? 99.528  106.111 123.915 1.00 43.14  ? 180 TYR A HB2  1 
ATOM 2535 H HB3  . TYR A 1 180 ? 101.041 106.571 123.993 1.00 41.98  ? 180 TYR A HB3  1 
ATOM 2536 H HD1  . TYR A 1 180 ? 100.484 106.768 120.748 1.00 46.78  ? 180 TYR A HD1  1 
ATOM 2537 H HD2  . TYR A 1 180 ? 99.395  108.729 124.060 1.00 48.53  ? 180 TYR A HD2  1 
ATOM 2538 H HE1  . TYR A 1 180 ? 99.988  108.626 119.485 1.00 52.41  ? 180 TYR A HE1  1 
ATOM 2539 H HE2  . TYR A 1 180 ? 98.899  110.588 122.794 1.00 49.04  ? 180 TYR A HE2  1 
ATOM 2540 H HH   . TYR A 1 180 ? 99.275  110.743 119.453 1.00 54.00  ? 180 TYR A HH   1 
ATOM 2541 N N    . LEU A 1 181 ? 100.929 103.460 124.451 1.00 42.04  ? 181 LEU A N    1 
ATOM 2542 C CA   . LEU A 1 181 ? 101.660 102.569 125.348 1.00 35.53  ? 181 LEU A CA   1 
ATOM 2543 C C    . LEU A 1 181 ? 102.371 101.470 124.566 1.00 34.72  ? 181 LEU A C    1 
ATOM 2544 O O    . LEU A 1 181 ? 103.536 101.150 124.836 1.00 34.16  ? 181 LEU A O    1 
ATOM 2545 C CB   . LEU A 1 181 ? 100.706 101.964 126.378 1.00 34.28  ? 181 LEU A CB   1 
ATOM 2546 C CG   . LEU A 1 181 ? 101.306 100.917 127.321 1.00 34.40  ? 181 LEU A CG   1 
ATOM 2547 C CD1  . LEU A 1 181 ? 102.520 101.479 128.048 1.00 37.46  ? 181 LEU A CD1  1 
ATOM 2548 C CD2  . LEU A 1 181 ? 100.265 100.424 128.314 1.00 37.75  ? 181 LEU A CD2  1 
ATOM 2549 H H    . LEU A 1 181 ? 100.079 103.482 124.580 1.00 41.19  ? 181 LEU A H    1 
ATOM 2550 H HA   . LEU A 1 181 ? 102.332 103.083 125.824 1.00 37.26  ? 181 LEU A HA   1 
ATOM 2551 H HB2  . LEU A 1 181 ? 100.358 102.682 126.930 1.00 37.21  ? 181 LEU A HB2  1 
ATOM 2552 H HB3  . LEU A 1 181 ? 99.974  101.539 125.904 1.00 37.28  ? 181 LEU A HB3  1 
ATOM 2553 H HG   . LEU A 1 181 ? 101.599 100.154 126.800 1.00 35.28  ? 181 LEU A HG   1 
ATOM 2554 H HD11 . LEU A 1 181 ? 102.793 100.852 128.736 1.00 38.39  ? 181 LEU A HD11 1 
ATOM 2555 H HD12 . LEU A 1 181 ? 103.240 101.606 127.411 1.00 35.60  ? 181 LEU A HD12 1 
ATOM 2556 H HD13 . LEU A 1 181 ? 102.280 102.328 128.452 1.00 37.02  ? 181 LEU A HD13 1 
ATOM 2557 H HD21 . LEU A 1 181 ? 100.679 99.780  128.910 1.00 37.71  ? 181 LEU A HD21 1 
ATOM 2558 H HD22 . LEU A 1 181 ? 99.931  101.179 128.823 1.00 36.50  ? 181 LEU A HD22 1 
ATOM 2559 H HD23 . LEU A 1 181 ? 99.539  100.005 127.827 1.00 38.49  ? 181 LEU A HD23 1 
ATOM 2560 N N    . GLN A 1 182 ? 101.675 100.871 123.595 1.00 41.60  ? 182 GLN A N    1 
ATOM 2561 C CA   . GLN A 1 182 ? 102.272 99.797  122.809 1.00 40.17  ? 182 GLN A CA   1 
ATOM 2562 C C    . GLN A 1 182 ? 103.460 100.298 122.001 1.00 42.38  ? 182 GLN A C    1 
ATOM 2563 O O    . GLN A 1 182 ? 104.498 99.632  121.933 1.00 46.00  ? 182 GLN A O    1 
ATOM 2564 C CB   . GLN A 1 182 ? 101.228 99.177  121.883 1.00 37.71  ? 182 GLN A CB   1 
ATOM 2565 C CG   . GLN A 1 182 ? 101.630 97.817  121.339 1.00 39.46  ? 182 GLN A CG   1 
ATOM 2566 C CD   . GLN A 1 182 ? 100.705 97.324  120.247 1.00 52.38  ? 182 GLN A CD   1 
ATOM 2567 O OE1  . GLN A 1 182 ? 100.040 98.113  119.578 1.00 52.61  ? 182 GLN A OE1  1 
ATOM 2568 N NE2  . GLN A 1 182 ? 100.657 96.012  120.062 1.00 57.01  ? 182 GLN A NE2  1 
ATOM 2569 H H    . GLN A 1 182 ? 100.867 101.067 123.377 1.00 41.06  ? 182 GLN A H    1 
ATOM 2570 H HA   . GLN A 1 182 ? 102.589 99.104  123.410 1.00 40.11  ? 182 GLN A HA   1 
ATOM 2571 H HB2  . GLN A 1 182 ? 100.399 99.067  122.375 1.00 41.49  ? 182 GLN A HB2  1 
ATOM 2572 H HB3  . GLN A 1 182 ? 101.087 99.770  121.129 1.00 42.02  ? 182 GLN A HB3  1 
ATOM 2573 H HG2  . GLN A 1 182 ? 102.525 97.875  120.971 1.00 40.30  ? 182 GLN A HG2  1 
ATOM 2574 H HG3  . GLN A 1 182 ? 101.609 97.171  122.062 1.00 44.90  ? 182 GLN A HG3  1 
ATOM 2575 H HE21 . GLN A 1 182 ? 101.136 95.491  120.551 1.00 56.00  ? 182 GLN A HE21 1 
ATOM 2576 H HE22 . GLN A 1 182 ? 100.146 95.681  119.454 1.00 54.58  ? 182 GLN A HE22 1 
ATOM 2577 N N    . MET A 1 183 ? 103.323 101.465 121.370 1.00 38.73  ? 183 MET A N    1 
ATOM 2578 C CA   . MET A 1 183 ? 104.452 102.063 120.667 1.00 37.20  ? 183 MET A CA   1 
ATOM 2579 C C    . MET A 1 183 ? 105.643 102.230 121.593 1.00 36.13  ? 183 MET A C    1 
ATOM 2580 O O    . MET A 1 183 ? 106.763 101.829 121.260 1.00 39.21  ? 183 MET A O    1 
ATOM 2581 C CB   . MET A 1 183 ? 104.052 103.416 120.081 1.00 41.78  ? 183 MET A CB   1 
ATOM 2582 C CG   . MET A 1 183 ? 103.585 103.379 118.645 1.00 48.67  ? 183 MET A CG   1 
ATOM 2583 S SD   . MET A 1 183 ? 104.066 104.901 117.809 1.00 69.57  ? 183 MET A SD   1 
ATOM 2584 C CE   . MET A 1 183 ? 105.644 104.412 117.121 1.00 63.15  ? 183 MET A CE   1 
ATOM 2585 H H    . MET A 1 183 ? 102.595 101.921 121.333 1.00 40.64  ? 183 MET A H    1 
ATOM 2586 H HA   . MET A 1 183 ? 104.707 101.480 119.935 1.00 40.55  ? 183 MET A HA   1 
ATOM 2587 H HB2  . MET A 1 183 ? 103.328 103.781 120.613 1.00 44.01  ? 183 MET A HB2  1 
ATOM 2588 H HB3  . MET A 1 183 ? 104.818 104.009 120.124 1.00 42.56  ? 183 MET A HB3  1 
ATOM 2589 H HG2  . MET A 1 183 ? 103.994 102.631 118.183 1.00 48.16  ? 183 MET A HG2  1 
ATOM 2590 H HG3  . MET A 1 183 ? 102.618 103.311 118.620 1.00 47.83  ? 183 MET A HG3  1 
ATOM 2591 H HE1  . MET A 1 183 ? 105.914 105.061 116.453 1.00 62.32  ? 183 MET A HE1  1 
ATOM 2592 H HE2  . MET A 1 183 ? 106.299 104.379 117.836 1.00 58.30  ? 183 MET A HE2  1 
ATOM 2593 H HE3  . MET A 1 183 ? 105.555 103.536 116.716 1.00 62.80  ? 183 MET A HE3  1 
ATOM 2594 N N    . ALA A 1 184 ? 105.424 102.828 122.765 1.00 36.67  ? 184 ALA A N    1 
ATOM 2595 C CA   . ALA A 1 184 ? 106.541 103.079 123.667 1.00 37.49  ? 184 ALA A CA   1 
ATOM 2596 C C    . ALA A 1 184 ? 107.219 101.775 124.066 1.00 40.02  ? 184 ALA A C    1 
ATOM 2597 O O    . ALA A 1 184 ? 108.450 101.654 124.003 1.00 47.10  ? 184 ALA A O    1 
ATOM 2598 C CB   . ALA A 1 184 ? 106.058 103.837 124.902 1.00 37.54  ? 184 ALA A CB   1 
ATOM 2599 H H    . ALA A 1 184 ? 104.657 103.091 123.053 1.00 38.67  ? 184 ALA A H    1 
ATOM 2600 H HA   . ALA A 1 184 ? 107.197 103.631 123.213 1.00 38.20  ? 184 ALA A HA   1 
ATOM 2601 H HB1  . ALA A 1 184 ? 105.451 103.272 125.405 1.00 38.53  ? 184 ALA A HB1  1 
ATOM 2602 H HB2  . ALA A 1 184 ? 106.827 104.067 125.445 1.00 36.13  ? 184 ALA A HB2  1 
ATOM 2603 H HB3  . ALA A 1 184 ? 105.603 104.645 124.618 1.00 38.10  ? 184 ALA A HB3  1 
ATOM 2604 N N    . VAL A 1 185 ? 106.427 100.777 124.458 1.00 37.80  ? 185 VAL A N    1 
ATOM 2605 C CA   . VAL A 1 185 ? 106.998 99.527  124.952 1.00 37.71  ? 185 VAL A CA   1 
ATOM 2606 C C    . VAL A 1 185 ? 107.754 98.808  123.841 1.00 36.88  ? 185 VAL A C    1 
ATOM 2607 O O    . VAL A 1 185 ? 108.883 98.343  124.039 1.00 37.93  ? 185 VAL A O    1 
ATOM 2608 C CB   . VAL A 1 185 ? 105.895 98.639  125.553 1.00 37.87  ? 185 VAL A CB   1 
ATOM 2609 C CG1  . VAL A 1 185 ? 106.347 97.187  125.617 1.00 36.17  ? 185 VAL A CG1  1 
ATOM 2610 C CG2  . VAL A 1 185 ? 105.505 99.148  126.933 1.00 38.19  ? 185 VAL A CG2  1 
ATOM 2611 H H    . VAL A 1 185 ? 105.567 100.798 124.448 1.00 38.03  ? 185 VAL A H    1 
ATOM 2612 H HA   . VAL A 1 185 ? 107.632 99.731  125.657 1.00 37.40  ? 185 VAL A HA   1 
ATOM 2613 H HB   . VAL A 1 185 ? 105.109 98.684  124.985 1.00 39.30  ? 185 VAL A HB   1 
ATOM 2614 H HG11 . VAL A 1 185 ? 107.286 97.153  125.855 1.00 36.62  ? 185 VAL A HG11 1 
ATOM 2615 H HG12 . VAL A 1 185 ? 105.821 96.725  126.289 1.00 38.02  ? 185 VAL A HG12 1 
ATOM 2616 H HG13 . VAL A 1 185 ? 106.204 96.773  124.752 1.00 36.27  ? 185 VAL A HG13 1 
ATOM 2617 H HG21 . VAL A 1 185 ? 105.879 100.033 127.061 1.00 37.94  ? 185 VAL A HG21 1 
ATOM 2618 H HG22 . VAL A 1 185 ? 104.538 99.187  126.992 1.00 38.85  ? 185 VAL A HG22 1 
ATOM 2619 H HG23 . VAL A 1 185 ? 105.852 98.541  127.606 1.00 36.48  ? 185 VAL A HG23 1 
ATOM 2620 N N    . SER A 1 186 ? 107.146 98.700  122.656 1.00 34.66  ? 186 SER A N    1 
ATOM 2621 C CA   . SER A 1 186 ? 107.791 97.983  121.561 1.00 35.17  ? 186 SER A CA   1 
ATOM 2622 C C    . SER A 1 186 ? 109.055 98.697  121.099 1.00 37.06  ? 186 SER A C    1 
ATOM 2623 O O    . SER A 1 186 ? 110.061 98.047  120.795 1.00 38.01  ? 186 SER A O    1 
ATOM 2624 C CB   . SER A 1 186 ? 106.814 97.813  120.400 1.00 42.09  ? 186 SER A CB   1 
ATOM 2625 O OG   . SER A 1 186 ? 105.762 96.931  120.749 1.00 45.71  ? 186 SER A OG   1 
ATOM 2626 H H    . SER A 1 186 ? 106.374 99.027  122.467 1.00 37.90  ? 186 SER A H    1 
ATOM 2627 H HA   . SER A 1 186 ? 108.044 97.099  121.871 1.00 36.66  ? 186 SER A HA   1 
ATOM 2628 H HB2  . SER A 1 186 ? 106.441 98.678  120.170 1.00 40.59  ? 186 SER A HB2  1 
ATOM 2629 H HB3  . SER A 1 186 ? 107.292 97.443  119.642 1.00 41.43  ? 186 SER A HB3  1 
ATOM 2630 H HG   . SER A 1 186 ? 105.234 96.843  120.102 1.00 44.57  ? 186 SER A HG   1 
ATOM 2631 N N    . GLY A 1 187 ? 109.024 100.030 121.031 1.00 42.90  ? 187 GLY A N    1 
ATOM 2632 C CA   . GLY A 1 187 ? 110.218 100.763 120.653 1.00 41.25  ? 187 GLY A CA   1 
ATOM 2633 C C    . GLY A 1 187 ? 111.338 100.609 121.663 1.00 41.02  ? 187 GLY A C    1 
ATOM 2634 O O    . GLY A 1 187 ? 112.504 100.462 121.291 1.00 45.06  ? 187 GLY A O    1 
ATOM 2635 H H    . GLY A 1 187 ? 108.336 100.519 121.197 1.00 41.72  ? 187 GLY A H    1 
ATOM 2636 H HA2  . GLY A 1 187 ? 110.534 100.445 119.793 1.00 40.06  ? 187 GLY A HA2  1 
ATOM 2637 H HA3  . GLY A 1 187 ? 110.005 101.705 120.572 1.00 41.06  ? 187 GLY A HA3  1 
ATOM 2638 N N    . THR A 1 188 ? 111.002 100.639 122.955 1.00 39.15  ? 188 THR A N    1 
ATOM 2639 C CA   . THR A 1 188 ? 112.026 100.437 123.975 1.00 36.29  ? 188 THR A CA   1 
ATOM 2640 C C    . THR A 1 188 ? 112.592 99.024  123.913 1.00 38.86  ? 188 THR A C    1 
ATOM 2641 O O    . THR A 1 188 ? 113.790 98.820  124.139 1.00 42.72  ? 188 THR A O    1 
ATOM 2642 C CB   . THR A 1 188 ? 111.450 100.723 125.362 1.00 41.06  ? 188 THR A CB   1 
ATOM 2643 O OG1  . THR A 1 188 ? 111.264 102.135 125.524 1.00 50.65  ? 188 THR A OG1  1 
ATOM 2644 C CG2  . THR A 1 188 ? 112.384 100.211 126.452 1.00 44.76  ? 188 THR A CG2  1 
ATOM 2645 H H    . THR A 1 188 ? 110.209 100.771 123.258 1.00 40.68  ? 188 THR A H    1 
ATOM 2646 H HA   . THR A 1 188 ? 112.754 101.059 123.818 1.00 39.22  ? 188 THR A HA   1 
ATOM 2647 H HB   . THR A 1 188 ? 110.596 100.274 125.455 1.00 40.56  ? 188 THR A HB   1 
ATOM 2648 H HG1  . THR A 1 188 ? 110.935 102.297 126.279 1.00 47.62  ? 188 THR A HG1  1 
ATOM 2649 H HG21 . THR A 1 188 ? 112.149 100.617 127.302 1.00 45.93  ? 188 THR A HG21 1 
ATOM 2650 H HG22 . THR A 1 188 ? 112.309 99.248  126.536 1.00 43.44  ? 188 THR A HG22 1 
ATOM 2651 H HG23 . THR A 1 188 ? 113.302 100.442 126.239 1.00 42.66  ? 188 THR A HG23 1 
ATOM 2652 N N    . ALA A 1 189 ? 111.747 98.035  123.614 1.00 40.90  ? 189 ALA A N    1 
ATOM 2653 C CA   . ALA A 1 189 ? 112.201 96.650  123.600 1.00 42.37  ? 189 ALA A CA   1 
ATOM 2654 C C    . ALA A 1 189 ? 113.019 96.313  122.360 1.00 42.39  ? 189 ALA A C    1 
ATOM 2655 O O    . ALA A 1 189 ? 113.942 95.495  122.440 1.00 41.79  ? 189 ALA A O    1 
ATOM 2656 C CB   . ALA A 1 189 ? 111.001 95.707  123.698 1.00 37.94  ? 189 ALA A CB   1 
ATOM 2657 H H    . ALA A 1 189 ? 110.916 98.141  123.418 1.00 40.13  ? 189 ALA A H    1 
ATOM 2658 H HA   . ALA A 1 189 ? 112.763 96.497  124.376 1.00 41.63  ? 189 ALA A HA   1 
ATOM 2659 H HB1  . ALA A 1 189 ? 111.319 94.791  123.689 1.00 37.81  ? 189 ALA A HB1  1 
ATOM 2660 H HB2  . ALA A 1 189 ? 110.528 95.885  124.526 1.00 39.35  ? 189 ALA A HB2  1 
ATOM 2661 H HB3  . ALA A 1 189 ? 110.415 95.862  122.941 1.00 38.98  ? 189 ALA A HB3  1 
ATOM 2662 N N    . ALA A 1 190 ? 112.704 96.921  121.213 1.00 39.90  ? 190 ALA A N    1 
ATOM 2663 C CA   . ALA A 1 190 ? 113.387 96.554  119.976 1.00 44.58  ? 190 ALA A CA   1 
ATOM 2664 C C    . ALA A 1 190 ? 114.876 96.868  120.030 1.00 46.01  ? 190 ALA A C    1 
ATOM 2665 O O    . ALA A 1 190 ? 115.669 96.225  119.334 1.00 47.62  ? 190 ALA A O    1 
ATOM 2666 C CB   . ALA A 1 190 ? 112.743 97.271  118.790 1.00 47.64  ? 190 ALA A CB   1 
ATOM 2667 H H    . ALA A 1 190 ? 112.111 97.538  121.128 1.00 40.35  ? 190 ALA A H    1 
ATOM 2668 H HA   . ALA A 1 190 ? 113.289 95.600  119.835 1.00 43.72  ? 190 ALA A HA   1 
ATOM 2669 H HB1  . ALA A 1 190 ? 111.809 97.015  118.735 1.00 46.19  ? 190 ALA A HB1  1 
ATOM 2670 H HB2  . ALA A 1 190 ? 112.816 98.229  118.925 1.00 45.37  ? 190 ALA A HB2  1 
ATOM 2671 H HB3  . ALA A 1 190 ? 113.205 97.015  117.977 1.00 45.56  ? 190 ALA A HB3  1 
ATOM 2672 N N    . ALA A 1 191 ? 115.277 97.848  120.842 1.00 41.75  ? 191 ALA A N    1 
ATOM 2673 C CA   . ALA A 1 191 ? 116.684 98.229  120.892 1.00 41.95  ? 191 ALA A CA   1 
ATOM 2674 C C    . ALA A 1 191 ? 117.550 97.125  121.484 1.00 45.99  ? 191 ALA A C    1 
ATOM 2675 O O    . ALA A 1 191 ? 118.752 97.067  121.201 1.00 51.00  ? 191 ALA A O    1 
ATOM 2676 C CB   . ALA A 1 191 ? 116.851 99.516  121.698 1.00 43.73  ? 191 ALA A CB   1 
ATOM 2677 H H    . ALA A 1 191 ? 114.764 98.299  121.364 1.00 42.76  ? 191 ALA A H    1 
ATOM 2678 H HA   . ALA A 1 191 ? 116.995 98.400  119.989 1.00 43.28  ? 191 ALA A HA   1 
ATOM 2679 H HB1  . ALA A 1 191 ? 117.791 99.756  121.715 1.00 44.02  ? 191 ALA A HB1  1 
ATOM 2680 H HB2  . ALA A 1 191 ? 116.336 100.221 121.277 1.00 43.88  ? 191 ALA A HB2  1 
ATOM 2681 H HB3  . ALA A 1 191 ? 116.531 99.366  122.601 1.00 43.29  ? 191 ALA A HB3  1 
ATOM 2682 N N    . PHE A 1 192 ? 116.971 96.250  122.304 1.00 47.92  ? 192 PHE A N    1 
ATOM 2683 C CA   . PHE A 1 192 ? 117.714 95.191  122.973 1.00 50.98  ? 192 PHE A CA   1 
ATOM 2684 C C    . PHE A 1 192 ? 117.515 93.827  122.323 1.00 43.60  ? 192 PHE A C    1 
ATOM 2685 O O    . PHE A 1 192 ? 117.881 92.811  122.922 1.00 41.70  ? 192 PHE A O    1 
ATOM 2686 C CB   . PHE A 1 192 ? 117.317 95.122  124.448 1.00 53.82  ? 192 PHE A CB   1 
ATOM 2687 C CG   . PHE A 1 192 ? 117.537 96.407  125.194 1.00 48.86  ? 192 PHE A CG   1 
ATOM 2688 C CD1  . PHE A 1 192 ? 118.763 96.689  125.772 1.00 47.42  ? 192 PHE A CD1  1 
ATOM 2689 C CD2  . PHE A 1 192 ? 116.515 97.331  125.320 1.00 42.25  ? 192 PHE A CD2  1 
ATOM 2690 C CE1  . PHE A 1 192 ? 118.965 97.872  126.458 1.00 50.82  ? 192 PHE A CE1  1 
ATOM 2691 C CE2  . PHE A 1 192 ? 116.711 98.513  126.006 1.00 43.15  ? 192 PHE A CE2  1 
ATOM 2692 C CZ   . PHE A 1 192 ? 117.937 98.784  126.575 1.00 51.62  ? 192 PHE A CZ   1 
ATOM 2693 H H    . PHE A 1 192 ? 116.132 96.252  122.493 1.00 45.84  ? 192 PHE A H    1 
ATOM 2694 H HA   . PHE A 1 192 ? 118.660 95.399  122.933 1.00 49.00  ? 192 PHE A HA   1 
ATOM 2695 H HB2  . PHE A 1 192 ? 116.376 94.899  124.510 1.00 49.60  ? 192 PHE A HB2  1 
ATOM 2696 H HB3  . PHE A 1 192 ? 117.847 94.434  124.881 1.00 50.24  ? 192 PHE A HB3  1 
ATOM 2697 H HD1  . PHE A 1 192 ? 119.459 96.077  125.695 1.00 47.63  ? 192 PHE A HD1  1 
ATOM 2698 H HD2  . PHE A 1 192 ? 115.686 97.153  124.938 1.00 43.87  ? 192 PHE A HD2  1 
ATOM 2699 H HE1  . PHE A 1 192 ? 119.792 98.051  126.842 1.00 49.53  ? 192 PHE A HE1  1 
ATOM 2700 H HE2  . PHE A 1 192 ? 116.016 99.126  126.083 1.00 44.01  ? 192 PHE A HE2  1 
ATOM 2701 H HZ   . PHE A 1 192 ? 118.070 99.579  127.037 1.00 51.33  ? 192 PHE A HZ   1 
ATOM 2702 N N    . ALA A 1 193 ? 116.948 93.776  121.125 1.00 46.22  ? 193 ALA A N    1 
ATOM 2703 C CA   . ALA A 1 193 ? 116.709 92.501  120.465 1.00 45.66  ? 193 ALA A CA   1 
ATOM 2704 C C    . ALA A 1 193 ? 118.040 91.822  120.153 1.00 39.22  ? 193 ALA A C    1 
ATOM 2705 O O    . ALA A 1 193 ? 118.881 92.419  119.465 1.00 40.71  ? 193 ALA A O    1 
ATOM 2706 C CB   . ALA A 1 193 ? 115.910 92.705  119.183 1.00 46.79  ? 193 ALA A CB   1 
ATOM 2707 H H    . ALA A 1 193 ? 116.695 94.462  120.673 1.00 46.04  ? 193 ALA A H    1 
ATOM 2708 H HA   . ALA A 1 193 ? 116.185 91.939  121.054 1.00 46.33  ? 193 ALA A HA   1 
ATOM 2709 H HB1  . ALA A 1 193 ? 115.755 91.842  118.768 1.00 46.63  ? 193 ALA A HB1  1 
ATOM 2710 H HB2  . ALA A 1 193 ? 115.064 93.125  119.403 1.00 46.49  ? 193 ALA A HB2  1 
ATOM 2711 H HB3  . ALA A 1 193 ? 116.416 93.275  118.582 1.00 45.97  ? 193 ALA A HB3  1 
ATOM 2712 N N    . PRO A 1 194 ? 118.278 90.599  120.629 1.00 37.85  ? 194 PRO A N    1 
ATOM 2713 C CA   . PRO A 1 194 ? 119.545 89.916  120.338 1.00 40.42  ? 194 PRO A CA   1 
ATOM 2714 C C    . PRO A 1 194 ? 119.568 89.118  119.043 1.00 42.31  ? 194 PRO A C    1 
ATOM 2715 O O    . PRO A 1 194 ? 120.625 88.578  118.698 1.00 44.07  ? 194 PRO A O    1 
ATOM 2716 C CB   . PRO A 1 194 ? 119.695 88.977  121.543 1.00 34.38  ? 194 PRO A CB   1 
ATOM 2717 C CG   . PRO A 1 194 ? 118.305 88.648  121.925 1.00 37.37  ? 194 PRO A CG   1 
ATOM 2718 C CD   . PRO A 1 194 ? 117.479 89.867  121.629 1.00 39.63  ? 194 PRO A CD   1 
ATOM 2719 H HA   . PRO A 1 194 ? 120.279 90.550  120.338 1.00 41.40  ? 194 PRO A HA   1 
ATOM 2720 H HB2  . PRO A 1 194 ? 120.180 88.179  121.281 1.00 34.92  ? 194 PRO A HB2  1 
ATOM 2721 H HB3  . PRO A 1 194 ? 120.151 89.439  122.264 1.00 37.19  ? 194 PRO A HB3  1 
ATOM 2722 H HG2  . PRO A 1 194 ? 117.996 87.893  121.400 1.00 39.92  ? 194 PRO A HG2  1 
ATOM 2723 H HG3  . PRO A 1 194 ? 118.272 88.439  122.871 1.00 37.64  ? 194 PRO A HG3  1 
ATOM 2724 H HD2  . PRO A 1 194 ? 116.622 89.611  121.254 1.00 41.77  ? 194 PRO A HD2  1 
ATOM 2725 H HD3  . PRO A 1 194 ? 117.372 90.401  122.432 1.00 40.25  ? 194 PRO A HD3  1 
ATOM 2726 N N    . THR A 1 195 ? 118.452 89.024  118.321 1.00 41.57  ? 195 THR A N    1 
ATOM 2727 C CA   . THR A 1 195 ? 118.399 88.226  117.106 1.00 41.16  ? 195 THR A CA   1 
ATOM 2728 C C    . THR A 1 195 ? 117.439 88.892  116.129 1.00 40.89  ? 195 THR A C    1 
ATOM 2729 O O    . THR A 1 195 ? 116.511 89.596  116.534 1.00 43.35  ? 195 THR A O    1 
ATOM 2730 C CB   . THR A 1 195 ? 117.964 86.786  117.411 1.00 41.77  ? 195 THR A CB   1 
ATOM 2731 O OG1  . THR A 1 195 ? 118.638 86.328  118.588 1.00 47.43  ? 195 THR A OG1  1 
ATOM 2732 C CG2  . THR A 1 195 ? 118.328 85.853  116.266 1.00 44.06  ? 195 THR A CG2  1 
ATOM 2733 H H    . THR A 1 195 ? 117.711 89.413  118.518 1.00 41.69  ? 195 THR A H    1 
ATOM 2734 H HA   . THR A 1 195 ? 119.279 88.199  116.698 1.00 43.15  ? 195 THR A HA   1 
ATOM 2735 H HB   . THR A 1 195 ? 117.004 86.754  117.548 1.00 42.63  ? 195 THR A HB   1 
ATOM 2736 H HG1  . THR A 1 195 ? 118.387 85.548  118.778 1.00 45.62  ? 195 THR A HG1  1 
ATOM 2737 H HG21 . THR A 1 195 ? 117.708 85.107  116.235 1.00 43.47  ? 195 THR A HG21 1 
ATOM 2738 H HG22 . THR A 1 195 ? 118.300 86.321  115.420 1.00 44.63  ? 195 THR A HG22 1 
ATOM 2739 H HG23 . THR A 1 195 ? 119.226 85.509  116.396 1.00 44.72  ? 195 THR A HG23 1 
ATOM 2740 N N    . PHE A 1 196 ? 117.674 88.662  114.837 1.00 42.52  ? 196 PHE A N    1 
ATOM 2741 C CA   . PHE A 1 196 ? 116.923 89.370  113.801 1.00 44.36  ? 196 PHE A CA   1 
ATOM 2742 C C    . PHE A 1 196 ? 115.417 89.153  113.890 1.00 42.48  ? 196 PHE A C    1 
ATOM 2743 O O    . PHE A 1 196 ? 114.669 90.147  113.840 1.00 43.55  ? 196 PHE A O    1 
ATOM 2744 C CB   . PHE A 1 196 ? 117.455 88.955  112.426 1.00 41.38  ? 196 PHE A CB   1 
ATOM 2745 C CG   . PHE A 1 196 ? 116.996 89.841  111.305 1.00 43.25  ? 196 PHE A CG   1 
ATOM 2746 C CD1  . PHE A 1 196 ? 117.431 91.151  111.219 1.00 48.39  ? 196 PHE A CD1  1 
ATOM 2747 C CD2  . PHE A 1 196 ? 116.133 89.362  110.336 1.00 45.38  ? 196 PHE A CD2  1 
ATOM 2748 C CE1  . PHE A 1 196 ? 117.012 91.968  110.190 1.00 50.39  ? 196 PHE A CE1  1 
ATOM 2749 C CE2  . PHE A 1 196 ? 115.711 90.175  109.305 1.00 51.57  ? 196 PHE A CE2  1 
ATOM 2750 C CZ   . PHE A 1 196 ? 116.152 91.479  109.232 1.00 54.38  ? 196 PHE A CZ   1 
ATOM 2751 H H    . PHE A 1 196 ? 118.260 88.111  114.534 1.00 43.67  ? 196 PHE A H    1 
ATOM 2752 H HA   . PHE A 1 196 ? 117.085 90.321  113.903 1.00 45.49  ? 196 PHE A HA   1 
ATOM 2753 H HB2  . PHE A 1 196 ? 118.424 88.982  112.446 1.00 44.54  ? 196 PHE A HB2  1 
ATOM 2754 H HB3  . PHE A 1 196 ? 117.156 88.054  112.230 1.00 42.66  ? 196 PHE A HB3  1 
ATOM 2755 H HD1  . PHE A 1 196 ? 118.012 91.486  111.864 1.00 47.76  ? 196 PHE A HD1  1 
ATOM 2756 H HD2  . PHE A 1 196 ? 115.833 88.484  110.381 1.00 46.51  ? 196 PHE A HD2  1 
ATOM 2757 H HE1  . PHE A 1 196 ? 117.310 92.847  110.143 1.00 50.00  ? 196 PHE A HE1  1 
ATOM 2758 H HE2  . PHE A 1 196 ? 115.130 89.843  108.659 1.00 52.41  ? 196 PHE A HE2  1 
ATOM 2759 H HZ   . PHE A 1 196 ? 115.869 92.027  108.538 1.00 53.68  ? 196 PHE A HZ   1 
ATOM 2760 N N    . PRO A 1 197 ? 114.902 87.925  114.000 1.00 36.72  ? 197 PRO A N    1 
ATOM 2761 C CA   . PRO A 1 197 ? 113.439 87.763  114.053 1.00 41.46  ? 197 PRO A CA   1 
ATOM 2762 C C    . PRO A 1 197 ? 112.785 88.508  115.204 1.00 38.81  ? 197 PRO A C    1 
ATOM 2763 O O    . PRO A 1 197 ? 111.660 88.999  115.050 1.00 40.48  ? 197 PRO A O    1 
ATOM 2764 C CB   . PRO A 1 197 ? 113.253 86.242  114.178 1.00 41.79  ? 197 PRO A CB   1 
ATOM 2765 C CG   . PRO A 1 197 ? 114.600 85.687  114.502 1.00 37.30  ? 197 PRO A CG   1 
ATOM 2766 C CD   . PRO A 1 197 ? 115.593 86.629  113.925 1.00 32.36  ? 197 PRO A CD   1 
ATOM 2767 H HA   . PRO A 1 197 ? 113.043 88.059  113.219 1.00 42.05  ? 197 PRO A HA   1 
ATOM 2768 H HB2  . PRO A 1 197 ? 112.626 86.049  114.892 1.00 41.06  ? 197 PRO A HB2  1 
ATOM 2769 H HB3  . PRO A 1 197 ? 112.931 85.884  113.336 1.00 41.08  ? 197 PRO A HB3  1 
ATOM 2770 H HG2  . PRO A 1 197 ? 114.704 85.633  115.465 1.00 39.11  ? 197 PRO A HG2  1 
ATOM 2771 H HG3  . PRO A 1 197 ? 114.693 84.809  114.101 1.00 37.71  ? 197 PRO A HG3  1 
ATOM 2772 H HD2  . PRO A 1 197 ? 116.392 86.630  114.467 1.00 36.56  ? 197 PRO A HD2  1 
ATOM 2773 H HD3  . PRO A 1 197 ? 115.784 86.396  113.003 1.00 37.58  ? 197 PRO A HD3  1 
ATOM 2774 N N    . VAL A 1 198 ? 113.450 88.611  116.354 1.00 35.91  ? 198 VAL A N    1 
ATOM 2775 C CA   . VAL A 1 198 ? 112.888 89.365  117.473 1.00 36.13  ? 198 VAL A CA   1 
ATOM 2776 C C    . VAL A 1 198 ? 112.739 90.836  117.095 1.00 38.50  ? 198 VAL A C    1 
ATOM 2777 O O    . VAL A 1 198 ? 111.707 91.469  117.361 1.00 43.55  ? 198 VAL A O    1 
ATOM 2778 C CB   . VAL A 1 198 ? 113.765 89.186  118.725 1.00 29.66  ? 198 VAL A CB   1 
ATOM 2779 C CG1  . VAL A 1 198 ? 113.272 90.066  119.856 1.00 30.03  ? 198 VAL A CG1  1 
ATOM 2780 C CG2  . VAL A 1 198 ? 113.786 87.725  119.150 1.00 27.40  ? 198 VAL A CG2  1 
ATOM 2781 H H    . VAL A 1 198 ? 114.219 88.258  116.510 1.00 37.48  ? 198 VAL A H    1 
ATOM 2782 H HA   . VAL A 1 198 ? 112.005 89.018  117.674 1.00 37.68  ? 198 VAL A HA   1 
ATOM 2783 H HB   . VAL A 1 198 ? 114.674 89.449  118.514 1.00 34.41  ? 198 VAL A HB   1 
ATOM 2784 H HG11 . VAL A 1 198 ? 113.462 90.993  119.644 1.00 31.93  ? 198 VAL A HG11 1 
ATOM 2785 H HG12 . VAL A 1 198 ? 112.317 89.938  119.964 1.00 33.50  ? 198 VAL A HG12 1 
ATOM 2786 H HG13 . VAL A 1 198 ? 113.735 89.818  120.672 1.00 32.75  ? 198 VAL A HG13 1 
ATOM 2787 H HG21 . VAL A 1 198 ? 113.231 87.211  118.543 1.00 31.28  ? 198 VAL A HG21 1 
ATOM 2788 H HG22 . VAL A 1 198 ? 114.699 87.401  119.118 1.00 31.38  ? 198 VAL A HG22 1 
ATOM 2789 H HG23 . VAL A 1 198 ? 113.441 87.653  120.054 1.00 30.30  ? 198 VAL A HG23 1 
ATOM 2790 N N    . TYR A 1 199 ? 113.774 91.401  116.469 1.00 36.02  ? 199 TYR A N    1 
ATOM 2791 C CA   . TYR A 1 199 ? 113.702 92.789  116.028 1.00 40.29  ? 199 TYR A CA   1 
ATOM 2792 C C    . TYR A 1 199 ? 112.587 92.977  115.009 1.00 46.22  ? 199 TYR A C    1 
ATOM 2793 O O    . TYR A 1 199 ? 111.856 93.974  115.053 1.00 53.27  ? 199 TYR A O    1 
ATOM 2794 C CB   . TYR A 1 199 ? 115.047 93.218  115.441 1.00 42.45  ? 199 TYR A CB   1 
ATOM 2795 C CG   . TYR A 1 199 ? 115.007 94.527  114.687 1.00 44.58  ? 199 TYR A CG   1 
ATOM 2796 C CD1  . TYR A 1 199 ? 115.146 95.737  115.351 1.00 53.99  ? 199 TYR A CD1  1 
ATOM 2797 C CD2  . TYR A 1 199 ? 114.831 94.554  113.310 1.00 46.04  ? 199 TYR A CD2  1 
ATOM 2798 C CE1  . TYR A 1 199 ? 115.112 96.936  114.667 1.00 65.26  ? 199 TYR A CE1  1 
ATOM 2799 C CE2  . TYR A 1 199 ? 114.794 95.749  112.618 1.00 52.44  ? 199 TYR A CE2  1 
ATOM 2800 C CZ   . TYR A 1 199 ? 114.935 96.936  113.302 1.00 62.63  ? 199 TYR A CZ   1 
ATOM 2801 O OH   . TYR A 1 199 ? 114.898 98.129  112.618 1.00 63.67  ? 199 TYR A OH   1 
ATOM 2802 H H    . TYR A 1 199 ? 114.517 91.006  116.291 1.00 39.20  ? 199 TYR A H    1 
ATOM 2803 H HA   . TYR A 1 199 ? 113.511 93.355  116.792 1.00 42.78  ? 199 TYR A HA   1 
ATOM 2804 H HB2  . TYR A 1 199 ? 115.686 93.314  116.165 1.00 43.89  ? 199 TYR A HB2  1 
ATOM 2805 H HB3  . TYR A 1 199 ? 115.351 92.533  114.826 1.00 43.92  ? 199 TYR A HB3  1 
ATOM 2806 H HD1  . TYR A 1 199 ? 115.266 95.741  116.273 1.00 51.65  ? 199 TYR A HD1  1 
ATOM 2807 H HD2  . TYR A 1 199 ? 114.735 93.754  112.846 1.00 48.08  ? 199 TYR A HD2  1 
ATOM 2808 H HE1  . TYR A 1 199 ? 115.205 97.739  115.126 1.00 61.04  ? 199 TYR A HE1  1 
ATOM 2809 H HE2  . TYR A 1 199 ? 114.674 95.752  111.696 1.00 53.75  ? 199 TYR A HE2  1 
ATOM 2810 H HH   . TYR A 1 199 ? 114.670 97.996  111.820 1.00 61.01  ? 199 TYR A HH   1 
ATOM 2811 N N    . CYS A 1 200 ? 112.440 92.028  114.081 1.00 42.70  ? 200 CYS A N    1 
ATOM 2812 C CA   . CYS A 1 200 ? 111.379 92.132  113.084 1.00 41.93  ? 200 CYS A CA   1 
ATOM 2813 C C    . CYS A 1 200 ? 110.003 92.091  113.738 1.00 43.55  ? 200 CYS A C    1 
ATOM 2814 O O    . CYS A 1 200 ? 109.102 92.852  113.362 1.00 46.21  ? 200 CYS A O    1 
ATOM 2815 C CB   . CYS A 1 200 ? 111.519 91.010  112.056 1.00 40.72  ? 200 CYS A CB   1 
ATOM 2816 S SG   . CYS A 1 200 ? 112.659 91.386  110.706 1.00 71.15  ? 200 CYS A SG   1 
ATOM 2817 H H    . CYS A 1 200 ? 112.934 91.328  114.009 1.00 42.48  ? 200 CYS A H    1 
ATOM 2818 H HA   . CYS A 1 200 ? 111.465 92.978  112.617 1.00 43.70  ? 200 CYS A HA   1 
ATOM 2819 H HB2  . CYS A 1 200 ? 111.845 90.214  112.505 1.00 42.01  ? 200 CYS A HB2  1 
ATOM 2820 H HB3  . CYS A 1 200 ? 110.648 90.833  111.667 1.00 44.72  ? 200 CYS A HB3  1 
ATOM 2821 H HG   . CYS A 1 200 ? 113.755 91.572  111.158 1.00 51.85  ? 200 CYS A HG   1 
ATOM 2822 N N    . LEU A 1 201 ? 109.821 91.205  114.718 1.00 38.16  ? 201 LEU A N    1 
ATOM 2823 C CA   . LEU A 1 201 ? 108.545 91.116  115.421 1.00 33.87  ? 201 LEU A CA   1 
ATOM 2824 C C    . LEU A 1 201 ? 108.222 92.422  116.137 1.00 37.81  ? 201 LEU A C    1 
ATOM 2825 O O    . LEU A 1 201 ? 107.093 92.928  116.064 1.00 40.72  ? 201 LEU A O    1 
ATOM 2826 C CB   . LEU A 1 201 ? 108.593 89.953  116.413 1.00 27.62  ? 201 LEU A CB   1 
ATOM 2827 C CG   . LEU A 1 201 ? 107.454 89.838  117.427 1.00 27.86  ? 201 LEU A CG   1 
ATOM 2828 C CD1  . LEU A 1 201 ? 106.103 89.858  116.731 1.00 33.45  ? 201 LEU A CD1  1 
ATOM 2829 C CD2  . LEU A 1 201 ? 107.619 88.577  118.258 1.00 28.57  ? 201 LEU A CD2  1 
ATOM 2830 H H    . LEU A 1 201 ? 110.417 90.647  114.991 1.00 38.89  ? 201 LEU A H    1 
ATOM 2831 H HA   . LEU A 1 201 ? 107.839 90.938  114.780 1.00 35.47  ? 201 LEU A HA   1 
ATOM 2832 H HB2  . LEU A 1 201 ? 108.603 89.127  115.905 1.00 31.71  ? 201 LEU A HB2  1 
ATOM 2833 H HB3  . LEU A 1 201 ? 109.417 90.024  116.919 1.00 32.57  ? 201 LEU A HB3  1 
ATOM 2834 H HG   . LEU A 1 201 ? 107.491 90.597  118.030 1.00 30.29  ? 201 LEU A HG   1 
ATOM 2835 H HD11 . LEU A 1 201 ? 106.092 89.170  116.047 1.00 32.98  ? 201 LEU A HD11 1 
ATOM 2836 H HD12 . LEU A 1 201 ? 105.410 89.683  117.387 1.00 33.00  ? 201 LEU A HD12 1 
ATOM 2837 H HD13 . LEU A 1 201 ? 105.966 90.728  116.327 1.00 34.56  ? 201 LEU A HD13 1 
ATOM 2838 H HD21 . LEU A 1 201 ? 107.607 87.807  117.669 1.00 29.62  ? 201 LEU A HD21 1 
ATOM 2839 H HD22 . LEU A 1 201 ? 108.466 88.620  118.730 1.00 28.89  ? 201 LEU A HD22 1 
ATOM 2840 H HD23 . LEU A 1 201 ? 106.889 88.520  118.894 1.00 30.52  ? 201 LEU A HD23 1 
ATOM 2841 N N    . PHE A 1 202 ? 109.207 92.988  116.835 1.00 39.73  ? 202 PHE A N    1 
ATOM 2842 C CA   . PHE A 1 202 ? 108.955 94.235  117.549 1.00 40.81  ? 202 PHE A CA   1 
ATOM 2843 C C    . PHE A 1 202 ? 108.679 95.380  116.581 1.00 47.24  ? 202 PHE A C    1 
ATOM 2844 O O    . PHE A 1 202 ? 107.842 96.246  116.861 1.00 51.66  ? 202 PHE A O    1 
ATOM 2845 C CB   . PHE A 1 202 ? 110.131 94.565  118.469 1.00 36.34  ? 202 PHE A CB   1 
ATOM 2846 C CG   . PHE A 1 202 ? 110.242 93.654  119.664 1.00 35.02  ? 202 PHE A CG   1 
ATOM 2847 C CD1  . PHE A 1 202 ? 109.110 93.244  120.352 1.00 35.43  ? 202 PHE A CD1  1 
ATOM 2848 C CD2  . PHE A 1 202 ? 111.476 93.210  120.102 1.00 38.95  ? 202 PHE A CD2  1 
ATOM 2849 C CE1  . PHE A 1 202 ? 109.209 92.410  121.445 1.00 41.78  ? 202 PHE A CE1  1 
ATOM 2850 C CE2  . PHE A 1 202 ? 111.578 92.376  121.198 1.00 39.92  ? 202 PHE A CE2  1 
ATOM 2851 C CZ   . PHE A 1 202 ? 110.443 91.976  121.869 1.00 41.02  ? 202 PHE A CZ   1 
ATOM 2852 H H    . PHE A 1 202 ? 110.007 92.680  116.909 1.00 39.52  ? 202 PHE A H    1 
ATOM 2853 H HA   . PHE A 1 202 ? 108.159 94.127  118.090 1.00 40.27  ? 202 PHE A HA   1 
ATOM 2854 H HB2  . PHE A 1 202 ? 110.955 94.488  117.962 1.00 39.52  ? 202 PHE A HB2  1 
ATOM 2855 H HB3  . PHE A 1 202 ? 110.029 95.472  118.795 1.00 39.24  ? 202 PHE A HB3  1 
ATOM 2856 H HD1  . PHE A 1 202 ? 108.272 93.533  120.071 1.00 37.00  ? 202 PHE A HD1  1 
ATOM 2857 H HD2  . PHE A 1 202 ? 112.246 93.475  119.653 1.00 39.61  ? 202 PHE A HD2  1 
ATOM 2858 H HE1  . PHE A 1 202 ? 108.441 92.143  121.897 1.00 41.02  ? 202 PHE A HE1  1 
ATOM 2859 H HE2  . PHE A 1 202 ? 112.413 92.083  121.483 1.00 39.45  ? 202 PHE A HE2  1 
ATOM 2860 H HZ   . PHE A 1 202 ? 110.512 91.414  122.607 1.00 40.65  ? 202 PHE A HZ   1 
ATOM 2861 N N    . ARG A 1 203 ? 109.358 95.398  115.433 1.00 46.29  ? 203 ARG A N    1 
ATOM 2862 C CA   . ARG A 1 203 ? 109.073 96.420  114.431 1.00 46.17  ? 203 ARG A CA   1 
ATOM 2863 C C    . ARG A 1 203 ? 107.653 96.280  113.892 1.00 45.26  ? 203 ARG A C    1 
ATOM 2864 O O    . ARG A 1 203 ? 106.961 97.281  113.669 1.00 52.03  ? 203 ARG A O    1 
ATOM 2865 C CB   . ARG A 1 203 ? 110.094 96.335  113.298 1.00 50.14  ? 203 ARG A CB   1 
ATOM 2866 C CG   . ARG A 1 203 ? 110.487 97.681  112.720 1.00 53.46  ? 203 ARG A CG   1 
ATOM 2867 C CD   . ARG A 1 203 ? 111.326 98.496  113.689 1.00 57.52  ? 203 ARG A CD   1 
ATOM 2868 N NE   . ARG A 1 203 ? 111.864 99.695  113.056 1.00 71.74  ? 203 ARG A NE   1 
ATOM 2869 C CZ   . ARG A 1 203 ? 111.220 100.850 112.961 1.00 67.58  ? 203 ARG A CZ   1 
ATOM 2870 N NH1  . ARG A 1 203 ? 109.999 101.005 113.446 1.00 61.61  ? 203 ARG A NH1  1 
ATOM 2871 N NH2  . ARG A 1 203 ? 111.816 101.877 112.361 1.00 62.92  ? 203 ARG A NH2  1 
ATOM 2872 H H    . ARG A 1 203 ? 109.975 94.840  115.215 1.00 45.74  ? 203 ARG A H    1 
ATOM 2873 H HA   . ARG A 1 203 ? 109.149 97.294  114.844 1.00 48.35  ? 203 ARG A HA   1 
ATOM 2874 H HB2  . ARG A 1 203 ? 110.900 95.912  113.635 1.00 49.94  ? 203 ARG A HB2  1 
ATOM 2875 H HB3  . ARG A 1 203 ? 109.719 95.802  112.580 1.00 50.48  ? 203 ARG A HB3  1 
ATOM 2876 H HG2  . ARG A 1 203 ? 111.005 97.542  111.912 1.00 55.71  ? 203 ARG A HG2  1 
ATOM 2877 H HG3  . ARG A 1 203 ? 109.685 98.186  112.520 1.00 55.13  ? 203 ARG A HG3  1 
ATOM 2878 H HD2  . ARG A 1 203 ? 110.781 98.766  114.444 1.00 56.77  ? 203 ARG A HD2  1 
ATOM 2879 H HD3  . ARG A 1 203 ? 112.073 97.957  113.994 1.00 56.74  ? 203 ARG A HD3  1 
ATOM 2880 H HE   . ARG A 1 203 ? 112.662 99.654  112.736 1.00 67.31  ? 203 ARG A HE   1 
ATOM 2881 H HH11 . ARG A 1 203 ? 109.601 100.350 113.835 1.00 61.14  ? 203 ARG A HH11 1 
ATOM 2882 H HH12 . ARG A 1 203 ? 109.602 101.764 113.371 1.00 61.85  ? 203 ARG A HH12 1 
ATOM 2883 H HH21 . ARG A 1 203 ? 112.609 101.788 112.042 1.00 63.36  ? 203 ARG A HH21 1 
ATOM 2884 H HH22 . ARG A 1 203 ? 111.407 102.631 112.293 1.00 62.28  ? 203 ARG A HH22 1 
ATOM 2885 N N    . PHE A 1 204 ? 107.202 95.043  113.672 1.00 37.50  ? 204 PHE A N    1 
ATOM 2886 C CA   . PHE A 1 204 ? 105.832 94.826  113.218 1.00 43.72  ? 204 PHE A CA   1 
ATOM 2887 C C    . PHE A 1 204 ? 104.825 95.329  114.249 1.00 47.04  ? 204 PHE A C    1 
ATOM 2888 O O    . PHE A 1 204 ? 103.818 95.960  113.895 1.00 52.79  ? 204 PHE A O    1 
ATOM 2889 C CB   . PHE A 1 204 ? 105.620 93.340  112.927 1.00 40.95  ? 204 PHE A CB   1 
ATOM 2890 C CG   . PHE A 1 204 ? 104.197 92.887  113.062 1.00 35.42  ? 204 PHE A CG   1 
ATOM 2891 C CD1  . PHE A 1 204 ? 103.248 93.248  112.124 1.00 38.85  ? 204 PHE A CD1  1 
ATOM 2892 C CD2  . PHE A 1 204 ? 103.808 92.099  114.129 1.00 35.97  ? 204 PHE A CD2  1 
ATOM 2893 C CE1  . PHE A 1 204 ? 101.939 92.829  112.247 1.00 45.78  ? 204 PHE A CE1  1 
ATOM 2894 C CE2  . PHE A 1 204 ? 102.501 91.679  114.258 1.00 44.01  ? 204 PHE A CE2  1 
ATOM 2895 C CZ   . PHE A 1 204 ? 101.565 92.045  113.316 1.00 48.66  ? 204 PHE A CZ   1 
ATOM 2896 H H    . PHE A 1 204 ? 107.664 94.325  113.777 1.00 41.31  ? 204 PHE A H    1 
ATOM 2897 H HA   . PHE A 1 204 ? 105.689 95.317  112.394 1.00 45.23  ? 204 PHE A HA   1 
ATOM 2898 H HB2  . PHE A 1 204 ? 105.904 93.157  112.018 1.00 42.52  ? 204 PHE A HB2  1 
ATOM 2899 H HB3  . PHE A 1 204 ? 106.155 92.821  113.548 1.00 41.02  ? 204 PHE A HB3  1 
ATOM 2900 H HD1  . PHE A 1 204 ? 103.496 93.777  111.400 1.00 42.34  ? 204 PHE A HD1  1 
ATOM 2901 H HD2  . PHE A 1 204 ? 104.437 91.849  114.768 1.00 38.67  ? 204 PHE A HD2  1 
ATOM 2902 H HE1  . PHE A 1 204 ? 101.309 93.078  111.610 1.00 45.57  ? 204 PHE A HE1  1 
ATOM 2903 H HE2  . PHE A 1 204 ? 102.252 91.149  114.980 1.00 43.65  ? 204 PHE A HE2  1 
ATOM 2904 H HZ   . PHE A 1 204 ? 100.683 91.763  113.401 1.00 45.44  ? 204 PHE A HZ   1 
ATOM 2905 N N    . LEU A 1 205 ? 105.078 95.061  115.532 1.00 40.71  ? 205 LEU A N    1 
ATOM 2906 C CA   . LEU A 1 205 ? 104.180 95.562  116.573 1.00 36.07  ? 205 LEU A CA   1 
ATOM 2907 C C    . LEU A 1 205 ? 104.182 97.089  116.614 1.00 45.25  ? 205 LEU A C    1 
ATOM 2908 O O    . LEU A 1 205 ? 103.131 97.721  116.806 1.00 48.19  ? 205 LEU A O    1 
ATOM 2909 C CB   . LEU A 1 205 ? 104.576 94.983  117.931 1.00 32.97  ? 205 LEU A CB   1 
ATOM 2910 C CG   . LEU A 1 205 ? 104.376 93.471  118.075 1.00 36.52  ? 205 LEU A CG   1 
ATOM 2911 C CD1  . LEU A 1 205 ? 104.968 92.972  119.382 1.00 42.06  ? 205 LEU A CD1  1 
ATOM 2912 C CD2  . LEU A 1 205 ? 102.907 93.094  117.977 1.00 35.84  ? 205 LEU A CD2  1 
ATOM 2913 H H    . LEU A 1 205 ? 105.746 94.603  115.821 1.00 41.05  ? 205 LEU A H    1 
ATOM 2914 H HA   . LEU A 1 205 ? 103.276 95.274  116.374 1.00 39.27  ? 205 LEU A HA   1 
ATOM 2915 H HB2  . LEU A 1 205 ? 105.516 95.169  118.083 1.00 37.84  ? 205 LEU A HB2  1 
ATOM 2916 H HB3  . LEU A 1 205 ? 104.045 95.415  118.618 1.00 37.94  ? 205 LEU A HB3  1 
ATOM 2917 H HG   . LEU A 1 205 ? 104.843 93.025  117.351 1.00 38.24  ? 205 LEU A HG   1 
ATOM 2918 H HD11 . LEU A 1 205 ? 104.524 93.418  120.120 1.00 41.96  ? 205 LEU A HD11 1 
ATOM 2919 H HD12 . LEU A 1 205 ? 104.830 92.013  119.444 1.00 38.14  ? 205 LEU A HD12 1 
ATOM 2920 H HD13 . LEU A 1 205 ? 105.917 93.171  119.395 1.00 40.92  ? 205 LEU A HD13 1 
ATOM 2921 H HD21 . LEU A 1 205 ? 102.803 92.162  118.223 1.00 36.30  ? 205 LEU A HD21 1 
ATOM 2922 H HD22 . LEU A 1 205 ? 102.396 93.655  118.582 1.00 37.89  ? 205 LEU A HD22 1 
ATOM 2923 H HD23 . LEU A 1 205 ? 102.605 93.231  117.066 1.00 38.76  ? 205 LEU A HD23 1 
ATOM 2924 N N    . VAL A 1 206 ? 105.356 97.699  116.440 1.00 47.21  ? 206 VAL A N    1 
ATOM 2925 C CA   . VAL A 1 206 ? 105.437 99.155  116.378 1.00 45.24  ? 206 VAL A CA   1 
ATOM 2926 C C    . VAL A 1 206 ? 104.587 99.682  115.231 1.00 48.71  ? 206 VAL A C    1 
ATOM 2927 O O    . VAL A 1 206 ? 103.891 100.694 115.368 1.00 52.34  ? 206 VAL A O    1 
ATOM 2928 C CB   . VAL A 1 206 ? 106.906 99.599  116.244 1.00 45.86  ? 206 VAL A CB   1 
ATOM 2929 C CG1  . VAL A 1 206 ? 107.000 100.981 115.614 1.00 51.35  ? 206 VAL A CG1  1 
ATOM 2930 C CG2  . VAL A 1 206 ? 107.595 99.577  117.598 1.00 43.47  ? 206 VAL A CG2  1 
ATOM 2931 H H    . VAL A 1 206 ? 106.111 97.296  116.356 1.00 45.75  ? 206 VAL A H    1 
ATOM 2932 H HA   . VAL A 1 206 ? 105.085 99.523  117.204 1.00 45.28  ? 206 VAL A HA   1 
ATOM 2933 H HB   . VAL A 1 206 ? 107.371 98.976  115.664 1.00 47.30  ? 206 VAL A HB   1 
ATOM 2934 H HG11 . VAL A 1 206 ? 107.898 101.321 115.744 1.00 53.80  ? 206 VAL A HG11 1 
ATOM 2935 H HG12 . VAL A 1 206 ? 106.813 100.917 114.664 1.00 52.53  ? 206 VAL A HG12 1 
ATOM 2936 H HG13 . VAL A 1 206 ? 106.360 101.570 116.043 1.00 51.40  ? 206 VAL A HG13 1 
ATOM 2937 H HG21 . VAL A 1 206 ? 108.446 100.036 117.530 1.00 47.17  ? 206 VAL A HG21 1 
ATOM 2938 H HG22 . VAL A 1 206 ? 107.030 100.022 118.250 1.00 43.10  ? 206 VAL A HG22 1 
ATOM 2939 H HG23 . VAL A 1 206 ? 107.737 98.654  117.860 1.00 43.26  ? 206 VAL A HG23 1 
ATOM 2940 N N    . ALA A 1 207 ? 104.643 99.016  114.076 1.00 50.82  ? 207 ALA A N    1 
ATOM 2941 C CA   . ALA A 1 207 ? 103.832 99.439  112.937 1.00 51.22  ? 207 ALA A CA   1 
ATOM 2942 C C    . ALA A 1 207 ? 102.344 99.331  113.249 1.00 49.44  ? 207 ALA A C    1 
ATOM 2943 O O    . ALA A 1 207 ? 101.552 100.209 112.875 1.00 53.71  ? 207 ALA A O    1 
ATOM 2944 C CB   . ALA A 1 207 ? 104.181 98.598  111.712 1.00 51.31  ? 207 ALA A CB   1 
ATOM 2945 H H    . ALA A 1 207 ? 105.137 98.328  113.928 1.00 50.05  ? 207 ALA A H    1 
ATOM 2946 H HA   . ALA A 1 207 ? 104.030 100.366 112.733 1.00 52.17  ? 207 ALA A HA   1 
ATOM 2947 H HB1  . ALA A 1 207 ? 105.121 98.712  111.509 1.00 51.86  ? 207 ALA A HB1  1 
ATOM 2948 H HB2  . ALA A 1 207 ? 103.996 97.666  111.906 1.00 49.17  ? 207 ALA A HB2  1 
ATOM 2949 H HB3  . ALA A 1 207 ? 103.642 98.893  110.961 1.00 52.51  ? 207 ALA A HB3  1 
ATOM 2950 N N    . PHE A 1 208 ? 101.943 98.247  113.914 1.00 45.87  ? 208 PHE A N    1 
ATOM 2951 C CA   . PHE A 1 208 ? 100.549 98.101  114.327 1.00 48.85  ? 208 PHE A CA   1 
ATOM 2952 C C    . PHE A 1 208 ? 100.108 99.298  115.162 1.00 52.16  ? 208 PHE A C    1 
ATOM 2953 O O    . PHE A 1 208 ? 99.070  99.929  114.892 1.00 55.49  ? 208 PHE A O    1 
ATOM 2954 C CB   . PHE A 1 208 ? 100.391 96.806  115.127 1.00 48.81  ? 208 PHE A CB   1 
ATOM 2955 C CG   . PHE A 1 208 ? 98.967  96.398  115.355 1.00 48.38  ? 208 PHE A CG   1 
ATOM 2956 C CD1  . PHE A 1 208 ? 98.188  97.037  116.302 1.00 51.91  ? 208 PHE A CD1  1 
ATOM 2957 C CD2  . PHE A 1 208 ? 98.418  95.347  114.645 1.00 50.50  ? 208 PHE A CD2  1 
ATOM 2958 C CE1  . PHE A 1 208 ? 96.879  96.654  116.515 1.00 63.64  ? 208 PHE A CE1  1 
ATOM 2959 C CE2  . PHE A 1 208 ? 97.112  94.957  114.853 1.00 58.62  ? 208 PHE A CE2  1 
ATOM 2960 C CZ   . PHE A 1 208 ? 96.342  95.611  115.791 1.00 63.01  ? 208 PHE A CZ   1 
ATOM 2961 H H    . PHE A 1 208 ? 102.453 97.593  114.139 1.00 48.24  ? 208 PHE A H    1 
ATOM 2962 H HA   . PHE A 1 208 ? 99.984  98.048  113.541 1.00 50.32  ? 208 PHE A HA   1 
ATOM 2963 H HB2  . PHE A 1 208 ? 100.831 96.088  114.646 1.00 48.94  ? 208 PHE A HB2  1 
ATOM 2964 H HB3  . PHE A 1 208 ? 100.808 96.923  115.995 1.00 48.89  ? 208 PHE A HB3  1 
ATOM 2965 H HD1  . PHE A 1 208 ? 98.545  97.744  116.790 1.00 52.58  ? 208 PHE A HD1  1 
ATOM 2966 H HD2  . PHE A 1 208 ? 98.933  94.905  114.009 1.00 49.94  ? 208 PHE A HD2  1 
ATOM 2967 H HE1  . PHE A 1 208 ? 96.362  97.096  117.149 1.00 60.95  ? 208 PHE A HE1  1 
ATOM 2968 H HE2  . PHE A 1 208 ? 96.752  94.253  114.363 1.00 55.06  ? 208 PHE A HE2  1 
ATOM 2969 H HZ   . PHE A 1 208 ? 95.461  95.349  115.934 1.00 57.95  ? 208 PHE A HZ   1 
ATOM 2970 N N    . ALA A 1 209 ? 100.898 99.627  116.185 1.00 49.08  ? 209 ALA A N    1 
ATOM 2971 C CA   . ALA A 1 209 ? 100.550 100.749 117.049 1.00 47.82  ? 209 ALA A CA   1 
ATOM 2972 C C    . ALA A 1 209 ? 100.537 102.061 116.279 1.00 51.16  ? 209 ALA A C    1 
ATOM 2973 O O    . ALA A 1 209 ? 99.704  102.934 116.553 1.00 55.48  ? 209 ALA A O    1 
ATOM 2974 C CB   . ALA A 1 209 ? 101.525 100.830 118.220 1.00 45.41  ? 209 ALA A CB   1 
ATOM 2975 H H    . ALA A 1 209 ? 101.630 99.228  116.392 1.00 49.05  ? 209 ALA A H    1 
ATOM 2976 H HA   . ALA A 1 209 ? 99.659  100.606 117.407 1.00 48.32  ? 209 ALA A HA   1 
ATOM 2977 H HB1  . ALA A 1 209 ? 101.499 99.992  118.707 1.00 46.00  ? 209 ALA A HB1  1 
ATOM 2978 H HB2  . ALA A 1 209 ? 102.418 100.988 117.876 1.00 47.59  ? 209 ALA A HB2  1 
ATOM 2979 H HB3  . ALA A 1 209 ? 101.261 101.561 118.800 1.00 46.29  ? 209 ALA A HB3  1 
ATOM 2980 N N    . VAL A 1 210 ? 101.446 102.220 115.315 1.00 47.63  ? 210 VAL A N    1 
ATOM 2981 C CA   . VAL A 1 210 ? 101.481 103.447 114.530 1.00 48.74  ? 210 VAL A CA   1 
ATOM 2982 C C    . VAL A 1 210 ? 100.201 103.599 113.727 1.00 47.54  ? 210 VAL A C    1 
ATOM 2983 O O    . VAL A 1 210 ? 99.637  104.694 113.639 1.00 49.34  ? 210 VAL A O    1 
ATOM 2984 C CB   . VAL A 1 210 ? 102.720 103.464 113.617 1.00 52.16  ? 210 VAL A CB   1 
ATOM 2985 C CG1  . VAL A 1 210 ? 102.559 104.498 112.512 1.00 50.81  ? 210 VAL A CG1  1 
ATOM 2986 C CG2  . VAL A 1 210 ? 103.968 103.740 114.429 1.00 51.64  ? 210 VAL A CG2  1 
ATOM 2987 H H    . VAL A 1 210 ? 102.044 101.641 115.095 1.00 49.85  ? 210 VAL A H    1 
ATOM 2988 H HA   . VAL A 1 210 ? 101.542 104.204 115.137 1.00 50.46  ? 210 VAL A HA   1 
ATOM 2989 H HB   . VAL A 1 210 ? 102.815 102.596 113.195 1.00 53.09  ? 210 VAL A HB   1 
ATOM 2990 H HG11 . VAL A 1 210 ? 103.432 104.685 112.135 1.00 51.70  ? 210 VAL A HG11 1 
ATOM 2991 H HG12 . VAL A 1 210 ? 101.975 104.144 111.823 1.00 51.35  ? 210 VAL A HG12 1 
ATOM 2992 H HG13 . VAL A 1 210 ? 102.180 105.309 112.887 1.00 50.48  ? 210 VAL A HG13 1 
ATOM 2993 H HG21 . VAL A 1 210 ? 103.790 103.512 115.354 1.00 51.19  ? 210 VAL A HG21 1 
ATOM 2994 H HG22 . VAL A 1 210 ? 104.697 103.199 114.088 1.00 53.04  ? 210 VAL A HG22 1 
ATOM 2995 H HG23 . VAL A 1 210 ? 104.191 104.681 114.357 1.00 53.39  ? 210 VAL A HG23 1 
ATOM 2996 N N    . ALA A 1 211 ? 99.720  102.509 113.125 1.00 43.62  ? 211 ALA A N    1 
ATOM 2997 C CA   . ALA A 1 211 ? 98.477  102.592 112.364 1.00 48.98  ? 211 ALA A CA   1 
ATOM 2998 C C    . ALA A 1 211 ? 97.308  102.953 113.271 1.00 54.80  ? 211 ALA A C    1 
ATOM 2999 O O    . ALA A 1 211 ? 96.468  103.799 112.919 1.00 61.19  ? 211 ALA A O    1 
ATOM 3000 C CB   . ALA A 1 211 ? 98.206  101.272 111.648 1.00 51.45  ? 211 ALA A CB   1 
ATOM 3001 H H    . ALA A 1 211 ? 100.080 101.728 113.141 1.00 48.21  ? 211 ALA A H    1 
ATOM 3002 H HA   . ALA A 1 211 ? 98.560  103.285 111.691 1.00 48.59  ? 211 ALA A HA   1 
ATOM 3003 H HB1  . ALA A 1 211 ? 98.078  100.576 112.311 1.00 50.73  ? 211 ALA A HB1  1 
ATOM 3004 H HB2  . ALA A 1 211 ? 97.408  101.362 111.105 1.00 50.38  ? 211 ALA A HB2  1 
ATOM 3005 H HB3  . ALA A 1 211 ? 98.963  101.056 111.082 1.00 50.98  ? 211 ALA A HB3  1 
ATOM 3006 N N    . GLY A 1 212 ? 97.241  102.325 114.447 1.00 53.80  ? 212 GLY A N    1 
ATOM 3007 C CA   . GLY A 1 212 ? 96.173  102.663 115.378 1.00 51.06  ? 212 GLY A CA   1 
ATOM 3008 C C    . GLY A 1 212 ? 96.187  104.131 115.761 1.00 55.16  ? 212 GLY A C    1 
ATOM 3009 O O    . GLY A 1 212 ? 95.155  104.813 115.723 1.00 57.57  ? 212 GLY A O    1 
ATOM 3010 H H    . GLY A 1 212 ? 97.787  101.721 114.719 1.00 52.45  ? 212 GLY A H    1 
ATOM 3011 H HA2  . GLY A 1 212 ? 95.315  102.460 114.973 1.00 52.18  ? 212 GLY A HA2  1 
ATOM 3012 H HA3  . GLY A 1 212 ? 96.264  102.130 116.183 1.00 52.27  ? 212 GLY A HA3  1 
ATOM 3013 N N    . VAL A 1 213 ? 97.367  104.643 116.120 1.00 53.62  ? 213 VAL A N    1 
ATOM 3014 C CA   . VAL A 1 213 ? 97.487  106.051 116.489 1.00 47.95  ? 213 VAL A CA   1 
ATOM 3015 C C    . VAL A 1 213 ? 97.057  106.934 115.327 1.00 52.90  ? 213 VAL A C    1 
ATOM 3016 O O    . VAL A 1 213 ? 96.294  107.895 115.497 1.00 56.21  ? 213 VAL A O    1 
ATOM 3017 C CB   . VAL A 1 213 ? 98.928  106.372 116.926 1.00 49.33  ? 213 VAL A CB   1 
ATOM 3018 C CG1  . VAL A 1 213 ? 99.259  107.833 116.648 1.00 45.50  ? 213 VAL A CG1  1 
ATOM 3019 C CG2  . VAL A 1 213 ? 99.127  106.065 118.396 1.00 54.70  ? 213 VAL A CG2  1 
ATOM 3020 H H    . VAL A 1 213 ? 98.103  104.199 116.156 1.00 52.81  ? 213 VAL A H    1 
ATOM 3021 H HA   . VAL A 1 213 ? 96.900  106.234 117.240 1.00 50.08  ? 213 VAL A HA   1 
ATOM 3022 H HB   . VAL A 1 213 ? 99.542  105.821 116.414 1.00 51.35  ? 213 VAL A HB   1 
ATOM 3023 H HG11 . VAL A 1 213 ? 100.064 108.067 117.136 1.00 48.27  ? 213 VAL A HG11 1 
ATOM 3024 H HG12 . VAL A 1 213 ? 99.409  107.953 115.698 1.00 48.62  ? 213 VAL A HG12 1 
ATOM 3025 H HG13 . VAL A 1 213 ? 98.524  108.391 116.946 1.00 45.36  ? 213 VAL A HG13 1 
ATOM 3026 H HG21 . VAL A 1 213 ? 100.047 106.256 118.636 1.00 52.89  ? 213 VAL A HG21 1 
ATOM 3027 H HG22 . VAL A 1 213 ? 98.527  106.618 118.919 1.00 50.93  ? 213 VAL A HG22 1 
ATOM 3028 H HG23 . VAL A 1 213 ? 98.936  105.131 118.549 1.00 50.67  ? 213 VAL A HG23 1 
ATOM 3029 N N    . MET A 1 214 ? 97.554  106.625 114.128 1.00 56.17  ? 214 MET A N    1 
ATOM 3030 C CA   . MET A 1 214 ? 97.279  107.468 112.974 1.00 54.25  ? 214 MET A CA   1 
ATOM 3031 C C    . MET A 1 214 ? 95.786  107.586 112.735 1.00 54.94  ? 214 MET A C    1 
ATOM 3032 O O    . MET A 1 214 ? 95.269  108.688 112.515 1.00 53.21  ? 214 MET A O    1 
ATOM 3033 C CB   . MET A 1 214 ? 97.962  106.900 111.732 1.00 59.68  ? 214 MET A CB   1 
ATOM 3034 C CG   . MET A 1 214 ? 98.540  107.958 110.812 1.00 58.89  ? 214 MET A CG   1 
ATOM 3035 S SD   . MET A 1 214 ? 99.484  107.284 109.428 1.00 80.31  ? 214 MET A SD   1 
ATOM 3036 C CE   . MET A 1 214 ? 98.525  105.830 109.000 1.00 64.01  ? 214 MET A CE   1 
ATOM 3037 H H    . MET A 1 214 ? 98.043  105.936 113.962 1.00 54.66  ? 214 MET A H    1 
ATOM 3038 H HA   . MET A 1 214 ? 97.646  108.352 113.137 1.00 53.48  ? 214 MET A HA   1 
ATOM 3039 H HB2  . MET A 1 214 ? 98.690  106.321 112.005 1.00 56.82  ? 214 MET A HB2  1 
ATOM 3040 H HB3  . MET A 1 214 ? 97.304  106.389 111.236 1.00 60.16  ? 214 MET A HB3  1 
ATOM 3041 H HG2  . MET A 1 214 ? 97.810  108.483 110.449 1.00 56.37  ? 214 MET A HG2  1 
ATOM 3042 H HG3  . MET A 1 214 ? 99.130  108.530 111.327 1.00 57.49  ? 214 MET A HG3  1 
ATOM 3043 H HE1  . MET A 1 214 ? 98.860  105.468 108.165 1.00 61.91  ? 214 MET A HE1  1 
ATOM 3044 H HE2  . MET A 1 214 ? 98.614  105.168 109.704 1.00 61.86  ? 214 MET A HE2  1 
ATOM 3045 H HE3  . MET A 1 214 ? 97.594  106.083 108.894 1.00 58.08  ? 214 MET A HE3  1 
ATOM 3046 N N    . MET A 1 215 ? 95.069  106.465 112.784 1.00 59.07  ? 215 MET A N    1 
ATOM 3047 C CA   . MET A 1 215 ? 93.630  106.533 112.563 1.00 58.16  ? 215 MET A CA   1 
ATOM 3048 C C    . MET A 1 215 ? 92.939  107.311 113.679 1.00 58.94  ? 215 MET A C    1 
ATOM 3049 O O    . MET A 1 215 ? 92.093  108.181 113.418 1.00 59.45  ? 215 MET A O    1 
ATOM 3050 C CB   . MET A 1 215 ? 93.050  105.125 112.448 1.00 58.42  ? 215 MET A CB   1 
ATOM 3051 C CG   . MET A 1 215 ? 93.151  104.542 111.045 1.00 66.10  ? 215 MET A CG   1 
ATOM 3052 S SD   . MET A 1 215 ? 92.252  102.997 110.777 1.00 81.72  ? 215 MET A SD   1 
ATOM 3053 C CE   . MET A 1 215 ? 91.751  102.543 112.435 1.00 65.13  ? 215 MET A CE   1 
ATOM 3054 H H    . MET A 1 215 ? 95.383  105.679 112.935 1.00 57.74  ? 215 MET A H    1 
ATOM 3055 H HA   . MET A 1 215 ? 93.468  106.991 111.724 1.00 57.41  ? 215 MET A HA   1 
ATOM 3056 H HB2  . MET A 1 215 ? 93.535  104.540 113.050 1.00 58.07  ? 215 MET A HB2  1 
ATOM 3057 H HB3  . MET A 1 215 ? 92.114  105.162 112.698 1.00 59.99  ? 215 MET A HB3  1 
ATOM 3058 H HG2  . MET A 1 215 ? 92.806  105.194 110.415 1.00 64.91  ? 215 MET A HG2  1 
ATOM 3059 H HG3  . MET A 1 215 ? 94.086  104.369 110.854 1.00 65.01  ? 215 MET A HG3  1 
ATOM 3060 H HE1  . MET A 1 215 ? 91.331  101.671 112.399 1.00 59.85  ? 215 MET A HE1  1 
ATOM 3061 H HE2  . MET A 1 215 ? 92.532  102.511 113.008 1.00 66.59  ? 215 MET A HE2  1 
ATOM 3062 H HE3  . MET A 1 215 ? 91.117  103.198 112.767 1.00 60.52  ? 215 MET A HE3  1 
ATOM 3063 N N    . ASN A 1 216 ? 93.299  107.028 114.935 1.00 56.57  ? 216 ASN A N    1 
ATOM 3064 C CA   . ASN A 1 216 ? 92.495  107.538 116.039 1.00 53.83  ? 216 ASN A CA   1 
ATOM 3065 C C    . ASN A 1 216 ? 92.678  109.038 116.242 1.00 59.57  ? 216 ASN A C    1 
ATOM 3066 O O    . ASN A 1 216 ? 91.704  109.745 116.531 1.00 63.43  ? 216 ASN A O    1 
ATOM 3067 C CB   . ASN A 1 216 ? 92.817  106.772 117.317 1.00 51.75  ? 216 ASN A CB   1 
ATOM 3068 C CG   . ASN A 1 216 ? 91.802  105.689 117.601 1.00 57.36  ? 216 ASN A CG   1 
ATOM 3069 O OD1  . ASN A 1 216 ? 90.810  105.923 118.289 1.00 51.36  ? 216 ASN A OD1  1 
ATOM 3070 N ND2  . ASN A 1 216 ? 92.028  104.504 117.050 1.00 61.40  ? 216 ASN A ND2  1 
ATOM 3071 H H    . ASN A 1 216 ? 93.979  106.556 115.165 1.00 56.54  ? 216 ASN A H    1 
ATOM 3072 H HA   . ASN A 1 216 ? 91.561  107.379 115.835 1.00 54.95  ? 216 ASN A HA   1 
ATOM 3073 H HB2  . ASN A 1 216 ? 93.688  106.356 117.230 1.00 54.40  ? 216 ASN A HB2  1 
ATOM 3074 H HB3  . ASN A 1 216 ? 92.808  107.390 118.064 1.00 52.22  ? 216 ASN A HB3  1 
ATOM 3075 H HD21 . ASN A 1 216 ? 92.729  104.378 116.571 1.00 57.80  ? 216 ASN A HD21 1 
ATOM 3076 H HD22 . ASN A 1 216 ? 91.475  103.858 117.181 1.00 55.29  ? 216 ASN A HD22 1 
ATOM 3077 N N    . THR A 1 217 ? 93.906  109.554 116.118 1.00 59.80  ? 217 THR A N    1 
ATOM 3078 C CA   . THR A 1 217 ? 94.078  110.996 116.300 1.00 58.13  ? 217 THR A CA   1 
ATOM 3079 C C    . THR A 1 217 ? 93.260  111.756 115.269 1.00 60.91  ? 217 THR A C    1 
ATOM 3080 O O    . THR A 1 217 ? 92.597  112.750 115.592 1.00 64.93  ? 217 THR A O    1 
ATOM 3081 C CB   . THR A 1 217 ? 95.542  111.419 116.174 1.00 61.40  ? 217 THR A CB   1 
ATOM 3082 O OG1  . THR A 1 217 ? 95.605  112.845 116.061 1.00 63.67  ? 217 THR A OG1  1 
ATOM 3083 C CG2  . THR A 1 217 ? 96.150  110.881 114.897 1.00 62.71  ? 217 THR A CG2  1 
ATOM 3084 H H    . THR A 1 217 ? 94.621  109.109 115.950 1.00 58.41  ? 217 THR A H    1 
ATOM 3085 H HA   . THR A 1 217 ? 93.761  111.252 117.183 1.00 57.85  ? 217 THR A HA   1 
ATOM 3086 H HB   . THR A 1 217 ? 96.052  111.111 116.936 1.00 58.79  ? 217 THR A HB   1 
ATOM 3087 H HG1  . THR A 1 217 ? 96.407  113.093 116.020 1.00 61.48  ? 217 THR A HG1  1 
ATOM 3088 H HG21 . THR A 1 217 ? 97.111  111.008 114.904 1.00 59.80  ? 217 THR A HG21 1 
ATOM 3089 H HG22 . THR A 1 217 ? 95.952  109.947 114.779 1.00 61.95  ? 217 THR A HG22 1 
ATOM 3090 H HG23 . THR A 1 217 ? 95.787  111.367 114.140 1.00 60.22  ? 217 THR A HG23 1 
ATOM 3091 N N    . GLY A 1 218 ? 93.304  111.303 114.015 1.00 60.97  ? 218 GLY A N    1 
ATOM 3092 C CA   . GLY A 1 218 ? 92.555  111.976 112.970 1.00 64.58  ? 218 GLY A CA   1 
ATOM 3093 C C    . GLY A 1 218 ? 91.063  111.922 113.222 1.00 63.08  ? 218 GLY A C    1 
ATOM 3094 O O    . GLY A 1 218 ? 90.358  112.922 113.059 1.00 66.53  ? 218 GLY A O    1 
ATOM 3095 H H    . GLY A 1 218 ? 93.755  110.620 113.752 1.00 59.88  ? 218 GLY A H    1 
ATOM 3096 H HA2  . GLY A 1 218 ? 92.830  112.903 112.916 1.00 62.68  ? 218 GLY A HA2  1 
ATOM 3097 H HA3  . GLY A 1 218 ? 92.742  111.553 112.117 1.00 63.54  ? 218 GLY A HA3  1 
ATOM 3098 N N    . THR A 1 219 ? 90.561  110.757 113.639 1.00 58.54  ? 219 THR A N    1 
ATOM 3099 C CA   . THR A 1 219 ? 89.132  110.647 113.919 1.00 59.14  ? 219 THR A CA   1 
ATOM 3100 C C    . THR A 1 219 ? 88.721  111.594 115.043 1.00 59.45  ? 219 THR A C    1 
ATOM 3101 O O    . THR A 1 219 ? 87.711  112.303 114.938 1.00 59.34  ? 219 THR A O    1 
ATOM 3102 C CB   . THR A 1 219 ? 88.782  109.201 114.273 1.00 62.19  ? 219 THR A CB   1 
ATOM 3103 O OG1  . THR A 1 219 ? 88.945  108.372 113.117 1.00 66.01  ? 219 THR A OG1  1 
ATOM 3104 C CG2  . THR A 1 219 ? 87.345  109.103 114.743 1.00 57.79  ? 219 THR A CG2  1 
ATOM 3105 H H    . THR A 1 219 ? 91.014  110.038 113.767 1.00 60.31  ? 219 THR A H    1 
ATOM 3106 H HA   . THR A 1 219 ? 88.637  110.894 113.121 1.00 59.60  ? 219 THR A HA   1 
ATOM 3107 H HB   . THR A 1 219 ? 89.361  108.889 114.986 1.00 61.06  ? 219 THR A HB   1 
ATOM 3108 H HG1  . THR A 1 219 ? 89.728  108.445 112.823 1.00 63.47  ? 219 THR A HG1  1 
ATOM 3109 H HG21 . THR A 1 219 ? 86.769  109.569 114.117 1.00 59.51  ? 219 THR A HG21 1 
ATOM 3110 H HG22 . THR A 1 219 ? 87.077  108.172 114.782 1.00 60.15  ? 219 THR A HG22 1 
ATOM 3111 H HG23 . THR A 1 219 ? 87.244  109.498 115.624 1.00 57.72  ? 219 THR A HG23 1 
ATOM 3112 N N    . LEU A 1 220 ? 89.501  111.629 116.127 1.00 65.04  ? 220 LEU A N    1 
ATOM 3113 C CA   . LEU A 1 220 ? 89.154  112.483 117.260 1.00 64.25  ? 220 LEU A CA   1 
ATOM 3114 C C    . LEU A 1 220 ? 89.161  113.952 116.858 1.00 68.89  ? 220 LEU A C    1 
ATOM 3115 O O    . LEU A 1 220 ? 88.215  114.703 117.159 1.00 70.25  ? 220 LEU A O    1 
ATOM 3116 C CB   . LEU A 1 220 ? 90.139  112.236 118.404 1.00 60.47  ? 220 LEU A CB   1 
ATOM 3117 C CG   . LEU A 1 220 ? 89.636  111.518 119.655 1.00 60.67  ? 220 LEU A CG   1 
ATOM 3118 C CD1  . LEU A 1 220 ? 90.779  111.368 120.641 1.00 65.36  ? 220 LEU A CD1  1 
ATOM 3119 C CD2  . LEU A 1 220 ? 88.480  112.267 120.288 1.00 61.08  ? 220 LEU A CD2  1 
ATOM 3120 H H    . LEU A 1 220 ? 90.229  111.183 116.226 1.00 63.29  ? 220 LEU A H    1 
ATOM 3121 H HA   . LEU A 1 220 ? 88.261  112.258 117.565 1.00 62.93  ? 220 LEU A HA   1 
ATOM 3122 H HB2  . LEU A 1 220 ? 90.875  111.708 118.059 1.00 61.06  ? 220 LEU A HB2  1 
ATOM 3123 H HB3  . LEU A 1 220 ? 90.481  113.096 118.694 1.00 62.56  ? 220 LEU A HB3  1 
ATOM 3124 H HG   . LEU A 1 220 ? 89.324  110.631 119.413 1.00 60.04  ? 220 LEU A HG   1 
ATOM 3125 H HD11 . LEU A 1 220 ? 90.468  110.877 121.417 1.00 61.44  ? 220 LEU A HD11 1 
ATOM 3126 H HD12 . LEU A 1 220 ? 91.500  110.883 120.210 1.00 60.80  ? 220 LEU A HD12 1 
ATOM 3127 H HD13 . LEU A 1 220 ? 91.086  112.249 120.907 1.00 63.78  ? 220 LEU A HD13 1 
ATOM 3128 H HD21 . LEU A 1 220 ? 88.697  113.212 120.319 1.00 63.65  ? 220 LEU A HD21 1 
ATOM 3129 H HD22 . LEU A 1 220 ? 87.683  112.126 119.754 1.00 60.23  ? 220 LEU A HD22 1 
ATOM 3130 H HD23 . LEU A 1 220 ? 88.340  111.928 121.185 1.00 60.21  ? 220 LEU A HD23 1 
ATOM 3131 N N    . VAL A 1 221 ? 90.211  114.374 116.147 1.00 70.72  ? 221 VAL A N    1 
ATOM 3132 C CA   . VAL A 1 221 ? 90.306  115.759 115.706 1.00 69.17  ? 221 VAL A CA   1 
ATOM 3133 C C    . VAL A 1 221 ? 89.120  116.108 114.820 1.00 69.08  ? 221 VAL A C    1 
ATOM 3134 O O    . VAL A 1 221 ? 88.494  117.160 114.986 1.00 66.64  ? 221 VAL A O    1 
ATOM 3135 C CB   . VAL A 1 221 ? 91.649  115.993 114.989 1.00 69.24  ? 221 VAL A CB   1 
ATOM 3136 C CG1  . VAL A 1 221 ? 91.538  117.126 113.987 1.00 74.98  ? 221 VAL A CG1  1 
ATOM 3137 C CG2  . VAL A 1 221 ? 92.743  116.291 116.005 1.00 65.27  ? 221 VAL A CG2  1 
ATOM 3138 H H    . VAL A 1 221 ? 90.875  113.881 115.914 1.00 67.05  ? 221 VAL A H    1 
ATOM 3139 H HA   . VAL A 1 221 ? 90.282  116.339 116.482 1.00 68.09  ? 221 VAL A HA   1 
ATOM 3140 H HB   . VAL A 1 221 ? 91.896  115.187 114.508 1.00 67.92  ? 221 VAL A HB   1 
ATOM 3141 H HG11 . VAL A 1 221 ? 92.434  117.381 113.717 1.00 73.18  ? 221 VAL A HG11 1 
ATOM 3142 H HG12 . VAL A 1 221 ? 91.039  116.824 113.212 1.00 71.40  ? 221 VAL A HG12 1 
ATOM 3143 H HG13 . VAL A 1 221 ? 91.093  117.881 114.403 1.00 73.23  ? 221 VAL A HG13 1 
ATOM 3144 H HG21 . VAL A 1 221 ? 93.582  116.428 115.538 1.00 63.23  ? 221 VAL A HG21 1 
ATOM 3145 H HG22 . VAL A 1 221 ? 92.506  117.091 116.499 1.00 65.51  ? 221 VAL A HG22 1 
ATOM 3146 H HG23 . VAL A 1 221 ? 92.822  115.539 116.611 1.00 65.08  ? 221 VAL A HG23 1 
ATOM 3147 N N    . MET A 1 222 ? 88.772  115.221 113.884 1.00 73.03  ? 222 MET A N    1 
ATOM 3148 C CA   . MET A 1 222 ? 87.619  115.481 113.031 1.00 76.30  ? 222 MET A CA   1 
ATOM 3149 C C    . MET A 1 222 ? 86.353  115.666 113.853 1.00 71.90  ? 222 MET A C    1 
ATOM 3150 O O    . MET A 1 222 ? 85.594  116.616 113.630 1.00 75.73  ? 222 MET A O    1 
ATOM 3151 C CB   . MET A 1 222 ? 87.420  114.341 112.034 1.00 80.02  ? 222 MET A CB   1 
ATOM 3152 C CG   . MET A 1 222 ? 87.825  114.676 110.612 1.00 86.50  ? 222 MET A CG   1 
ATOM 3153 S SD   . MET A 1 222 ? 87.106  113.526 109.423 1.00 107.55 ? 222 MET A SD   1 
ATOM 3154 C CE   . MET A 1 222 ? 88.552  113.016 108.502 1.00 90.80  ? 222 MET A CE   1 
ATOM 3155 H H    . MET A 1 222 ? 89.181  114.481 113.728 1.00 70.83  ? 222 MET A H    1 
ATOM 3156 H HA   . MET A 1 222 ? 87.787  116.292 112.524 1.00 75.62  ? 222 MET A HA   1 
ATOM 3157 H HB2  . MET A 1 222 ? 87.952  113.581 112.321 1.00 75.55  ? 222 MET A HB2  1 
ATOM 3158 H HB3  . MET A 1 222 ? 86.482  114.097 112.029 1.00 77.62  ? 222 MET A HB3  1 
ATOM 3159 H HG2  . MET A 1 222 ? 87.513  115.567 110.393 1.00 83.36  ? 222 MET A HG2  1 
ATOM 3160 H HG3  . MET A 1 222 ? 88.789  114.633 110.538 1.00 85.15  ? 222 MET A HG3  1 
ATOM 3161 H HE1  . MET A 1 222 ? 88.338  112.209 108.009 1.00 91.53  ? 222 MET A HE1  1 
ATOM 3162 H HE2  . MET A 1 222 ? 88.795  113.722 107.883 1.00 91.88  ? 222 MET A HE2  1 
ATOM 3163 H HE3  . MET A 1 222 ? 89.278  112.844 109.124 1.00 87.94  ? 222 MET A HE3  1 
ATOM 3164 N N    . GLU A 1 223 ? 86.104  114.773 114.812 1.00 70.04  ? 223 GLU A N    1 
ATOM 3165 C CA   . GLU A 1 223 ? 84.841  114.848 115.541 1.00 70.20  ? 223 GLU A CA   1 
ATOM 3166 C C    . GLU A 1 223 ? 84.727  116.145 116.331 1.00 69.40  ? 223 GLU A C    1 
ATOM 3167 O O    . GLU A 1 223 ? 83.691  116.817 116.278 1.00 69.41  ? 223 GLU A O    1 
ATOM 3168 C CB   . GLU A 1 223 ? 84.669  113.642 116.466 1.00 66.18  ? 223 GLU A CB   1 
ATOM 3169 C CG   . GLU A 1 223 ? 83.679  112.595 115.953 1.00 73.12  ? 223 GLU A CG   1 
ATOM 3170 C CD   . GLU A 1 223 ? 84.309  111.544 115.065 1.00 81.06  ? 223 GLU A CD   1 
ATOM 3171 O OE1  . GLU A 1 223 ? 83.600  111.007 114.189 1.00 85.26  ? 223 GLU A OE1  1 
ATOM 3172 O OE2  . GLU A 1 223 ? 85.503  111.240 115.249 1.00 75.39  ? 223 GLU A OE2  1 
ATOM 3173 H H    . GLU A 1 223 ? 86.632  114.139 115.053 1.00 70.18  ? 223 GLU A H    1 
ATOM 3174 H HA   . GLU A 1 223 ? 84.117  114.836 114.899 1.00 71.58  ? 223 GLU A HA   1 
ATOM 3175 H HB2  . GLU A 1 223 ? 85.530  113.213 116.578 1.00 67.17  ? 223 GLU A HB2  1 
ATOM 3176 H HB3  . GLU A 1 223 ? 84.341  113.957 117.323 1.00 67.26  ? 223 GLU A HB3  1 
ATOM 3177 H HG2  . GLU A 1 223 ? 83.287  112.140 116.716 1.00 71.80  ? 223 GLU A HG2  1 
ATOM 3178 H HG3  . GLU A 1 223 ? 82.980  113.036 115.445 1.00 75.30  ? 223 GLU A HG3  1 
ATOM 3179 N N    . TRP A 1 224 ? 85.774  116.529 117.066 1.00 69.81  ? 224 TRP A N    1 
ATOM 3180 C CA   . TRP A 1 224 ? 85.567  117.651 117.982 1.00 71.72  ? 224 TRP A CA   1 
ATOM 3181 C C    . TRP A 1 224 ? 85.507  119.005 117.274 1.00 74.82  ? 224 TRP A C    1 
ATOM 3182 O O    . TRP A 1 224 ? 84.709  119.864 117.664 1.00 69.37  ? 224 TRP A O    1 
ATOM 3183 C CB   . TRP A 1 224 ? 86.631  117.663 119.080 1.00 64.92  ? 224 TRP A CB   1 
ATOM 3184 C CG   . TRP A 1 224 ? 86.217  116.875 120.297 1.00 60.48  ? 224 TRP A CG   1 
ATOM 3185 C CD1  . TRP A 1 224 ? 86.927  115.895 120.922 1.00 63.90  ? 224 TRP A CD1  1 
ATOM 3186 C CD2  . TRP A 1 224 ? 84.986  117.005 121.028 1.00 59.60  ? 224 TRP A CD2  1 
ATOM 3187 N NE1  . TRP A 1 224 ? 86.220  115.408 121.996 1.00 62.76  ? 224 TRP A NE1  1 
ATOM 3188 C CE2  . TRP A 1 224 ? 85.025  116.072 122.081 1.00 60.57  ? 224 TRP A CE2  1 
ATOM 3189 C CE3  . TRP A 1 224 ? 83.856  117.818 120.891 1.00 65.77  ? 224 TRP A CE3  1 
ATOM 3190 C CZ2  . TRP A 1 224 ? 83.980  115.930 122.992 1.00 64.66  ? 224 TRP A CZ2  1 
ATOM 3191 C CZ3  . TRP A 1 224 ? 82.820  117.675 121.796 1.00 68.68  ? 224 TRP A CZ3  1 
ATOM 3192 C CH2  . TRP A 1 224 ? 82.889  116.739 122.833 1.00 68.40  ? 224 TRP A CH2  1 
ATOM 3193 H H    . TRP A 1 224 ? 86.561  116.181 117.058 1.00 69.42  ? 224 TRP A H    1 
ATOM 3194 H HA   . TRP A 1 224 ? 84.707  117.523 118.406 1.00 69.62  ? 224 TRP A HA   1 
ATOM 3195 H HB2  . TRP A 1 224 ? 87.448  117.273 118.734 1.00 66.04  ? 224 TRP A HB2  1 
ATOM 3196 H HB3  . TRP A 1 224 ? 86.791  118.579 119.356 1.00 65.99  ? 224 TRP A HB3  1 
ATOM 3197 H HD1  . TRP A 1 224 ? 87.770  115.600 120.662 1.00 64.72  ? 224 TRP A HD1  1 
ATOM 3198 H HE1  . TRP A 1 224 ? 86.484  114.786 122.528 1.00 63.05  ? 224 TRP A HE1  1 
ATOM 3199 H HE3  . TRP A 1 224 ? 83.800  118.443 120.204 1.00 67.04  ? 224 TRP A HE3  1 
ATOM 3200 H HZ2  . TRP A 1 224 ? 84.023  115.308 123.683 1.00 63.87  ? 224 TRP A HZ2  1 
ATOM 3201 H HZ3  . TRP A 1 224 ? 82.063  118.211 121.715 1.00 67.89  ? 224 TRP A HZ3  1 
ATOM 3202 H HH2  . TRP A 1 224 ? 82.178  116.665 123.428 1.00 67.55  ? 224 TRP A HH2  1 
ATOM 3203 N N    . THR A 1 225 ? 86.324  119.234 116.248 1.00 76.94  ? 225 THR A N    1 
ATOM 3204 C CA   . THR A 1 225 ? 86.368  120.564 115.645 1.00 71.75  ? 225 THR A CA   1 
ATOM 3205 C C    . THR A 1 225 ? 85.052  120.896 114.948 1.00 71.20  ? 225 THR A C    1 
ATOM 3206 O O    . THR A 1 225 ? 84.339  120.015 114.461 1.00 75.36  ? 225 THR A O    1 
ATOM 3207 C CB   . THR A 1 225 ? 87.509  120.692 114.632 1.00 78.71  ? 225 THR A CB   1 
ATOM 3208 O OG1  . THR A 1 225 ? 87.309  121.873 113.847 1.00 88.53  ? 225 THR A OG1  1 
ATOM 3209 C CG2  . THR A 1 225 ? 87.547  119.508 113.682 1.00 76.73  ? 225 THR A CG2  1 
ATOM 3210 H H    . THR A 1 225 ? 86.849  118.651 115.898 1.00 74.27  ? 225 THR A H    1 
ATOM 3211 H HA   . THR A 1 225 ? 86.509  121.222 116.344 1.00 72.93  ? 225 THR A HA   1 
ATOM 3212 H HB   . THR A 1 225 ? 88.357  120.747 115.099 1.00 77.33  ? 225 THR A HB   1 
ATOM 3213 H HG1  . THR A 1 225 ? 87.934  121.960 113.293 1.00 84.77  ? 225 THR A HG1  1 
ATOM 3214 H HG21 . THR A 1 225 ? 88.398  119.054 113.758 1.00 74.11  ? 225 THR A HG21 1 
ATOM 3215 H HG22 . THR A 1 225 ? 86.827  118.887 113.871 1.00 74.75  ? 225 THR A HG22 1 
ATOM 3216 H HG23 . THR A 1 225 ? 87.451  119.825 112.771 1.00 76.18  ? 225 THR A HG23 1 
ATOM 3217 N N    . SER A 1 226 ? 84.744  122.191 114.896 1.00 72.89  ? 226 SER A N    1 
ATOM 3218 C CA   . SER A 1 226 ? 83.546  122.662 114.216 1.00 79.40  ? 226 SER A CA   1 
ATOM 3219 C C    . SER A 1 226 ? 83.616  122.352 112.721 1.00 87.79  ? 226 SER A C    1 
ATOM 3220 O O    . SER A 1 226 ? 84.675  122.043 112.168 1.00 89.78  ? 226 SER A O    1 
ATOM 3221 C CB   . SER A 1 226 ? 83.368  124.165 114.432 1.00 81.36  ? 226 SER A CB   1 
ATOM 3222 O OG   . SER A 1 226 ? 82.246  124.657 113.718 1.00 87.54  ? 226 SER A OG   1 
ATOM 3223 H H    . SER A 1 226 ? 85.214  122.818 115.250 1.00 75.86  ? 226 SER A H    1 
ATOM 3224 H HA   . SER A 1 226 ? 82.770  122.210 114.582 1.00 78.65  ? 226 SER A HA   1 
ATOM 3225 H HB2  . SER A 1 226 ? 83.234  124.333 115.378 1.00 79.85  ? 226 SER A HB2  1 
ATOM 3226 H HB3  . SER A 1 226 ? 84.164  124.626 114.124 1.00 81.06  ? 226 SER A HB3  1 
ATOM 3227 H HG   . SER A 1 226 ? 81.544  124.290 113.998 1.00 83.70  ? 226 SER A HG   1 
ATOM 3228 N N    . ALA A 1 227 ? 82.457  122.443 112.065 1.00 87.88  ? 227 ALA A N    1 
ATOM 3229 C CA   . ALA A 1 227 ? 82.361  122.049 110.663 1.00 87.13  ? 227 ALA A CA   1 
ATOM 3230 C C    . ALA A 1 227 ? 83.192  122.954 109.761 1.00 91.58  ? 227 ALA A C    1 
ATOM 3231 O O    . ALA A 1 227 ? 83.866  122.475 108.842 1.00 89.12  ? 227 ALA A O    1 
ATOM 3232 C CB   . ALA A 1 227 ? 80.898  122.057 110.220 1.00 83.71  ? 227 ALA A CB   1 
ATOM 3233 H H    . ALA A 1 227 ? 81.719  122.726 112.407 1.00 85.37  ? 227 ALA A H    1 
ATOM 3234 H HA   . ALA A 1 227 ? 82.699  121.148 110.563 1.00 85.81  ? 227 ALA A HA   1 
ATOM 3235 H HB1  . ALA A 1 227 ? 80.846  121.783 109.291 1.00 85.25  ? 227 ALA A HB1  1 
ATOM 3236 H HB2  . ALA A 1 227 ? 80.397  121.440 110.776 1.00 85.61  ? 227 ALA A HB2  1 
ATOM 3237 H HB3  . ALA A 1 227 ? 80.544  122.954 110.321 1.00 84.46  ? 227 ALA A HB3  1 
ATOM 3238 N N    . GLN A 1 228 ? 83.156  124.265 110.002 1.00 96.64  ? 228 GLN A N    1 
ATOM 3239 C CA   . GLN A 1 228 ? 83.784  125.205 109.081 1.00 99.43  ? 228 GLN A CA   1 
ATOM 3240 C C    . GLN A 1 228 ? 85.306  125.131 109.099 1.00 97.75  ? 228 GLN A C    1 
ATOM 3241 O O    . GLN A 1 228 ? 85.945  125.656 108.181 1.00 101.27 ? 228 GLN A O    1 
ATOM 3242 C CB   . GLN A 1 228 ? 83.340  126.634 109.401 1.00 98.53  ? 228 GLN A CB   1 
ATOM 3243 C CG   . GLN A 1 228 ? 83.734  127.119 110.787 1.00 98.56  ? 228 GLN A CG   1 
ATOM 3244 C CD   . GLN A 1 228 ? 82.688  128.028 111.403 1.00 104.93 ? 228 GLN A CD   1 
ATOM 3245 O OE1  . GLN A 1 228 ? 82.617  129.215 111.086 1.00 114.07 ? 228 GLN A OE1  1 
ATOM 3246 N NE2  . GLN A 1 228 ? 81.868  127.473 112.288 1.00 103.11 ? 228 GLN A NE2  1 
ATOM 3247 H H    . GLN A 1 228 ? 82.778  124.630 110.683 1.00 94.85  ? 228 GLN A H    1 
ATOM 3248 H HA   . GLN A 1 228 ? 83.490  125.000 108.180 1.00 97.48  ? 228 GLN A HA   1 
ATOM 3249 H HB2  . GLN A 1 228 ? 83.741  127.236 108.754 1.00 99.25  ? 228 GLN A HB2  1 
ATOM 3250 H HB3  . GLN A 1 228 ? 82.373  126.682 109.336 1.00 98.25  ? 228 GLN A HB3  1 
ATOM 3251 H HG2  . GLN A 1 228 ? 83.849  126.354 111.372 1.00 97.50  ? 228 GLN A HG2  1 
ATOM 3252 H HG3  . GLN A 1 228 ? 84.564  127.617 110.724 1.00 100.33 ? 228 GLN A HG3  1 
ATOM 3253 H HE21 . GLN A 1 228 ? 81.947  126.640 112.484 1.00 99.74  ? 228 GLN A HE21 1 
ATOM 3254 H HE22 . GLN A 1 228 ? 81.257  127.947 112.664 1.00 102.58 ? 228 GLN A HE22 1 
ATOM 3255 N N    . ALA A 1 229 ? 85.904  124.500 110.110 1.00 90.21  ? 229 ALA A N    1 
ATOM 3256 C CA   . ALA A 1 229 ? 87.353  124.504 110.284 1.00 86.48  ? 229 ALA A CA   1 
ATOM 3257 C C    . ALA A 1 229 ? 87.940  123.095 110.287 1.00 83.84  ? 229 ALA A C    1 
ATOM 3258 O O    . ALA A 1 229 ? 88.938  122.839 110.964 1.00 84.96  ? 229 ALA A O    1 
ATOM 3259 C CB   . ALA A 1 229 ? 87.730  125.236 111.571 1.00 86.45  ? 229 ALA A CB   1 
ATOM 3260 H H    . ALA A 1 229 ? 85.485  124.058 110.717 1.00 90.61  ? 229 ALA A H    1 
ATOM 3261 H HA   . ALA A 1 229 ? 87.756  124.986 109.546 1.00 89.67  ? 229 ALA A HA   1 
ATOM 3262 H HB1  . ALA A 1 229 ? 88.696  125.241 111.662 1.00 87.32  ? 229 ALA A HB1  1 
ATOM 3263 H HB2  . ALA A 1 229 ? 87.396  126.146 111.526 1.00 88.29  ? 229 ALA A HB2  1 
ATOM 3264 H HB3  . ALA A 1 229 ? 87.329  124.774 112.325 1.00 86.33  ? 229 ALA A HB3  1 
ATOM 3265 N N    . ARG A 1 230 ? 87.341  122.168 109.541 1.00 86.48  ? 230 ARG A N    1 
ATOM 3266 C CA   . ARG A 1 230 ? 87.845  120.799 109.519 1.00 91.53  ? 230 ARG A CA   1 
ATOM 3267 C C    . ARG A 1 230 ? 89.072  120.682 108.613 1.00 93.20  ? 230 ARG A C    1 
ATOM 3268 O O    . ARG A 1 230 ? 90.130  120.217 109.066 1.00 90.86  ? 230 ARG A O    1 
ATOM 3269 C CB   . ARG A 1 230 ? 86.745  119.826 109.080 1.00 91.19  ? 230 ARG A CB   1 
ATOM 3270 C CG   . ARG A 1 230 ? 85.733  119.483 110.173 1.00 86.29  ? 230 ARG A CG   1 
ATOM 3271 C CD   . ARG A 1 230 ? 85.397  117.997 110.187 1.00 84.42  ? 230 ARG A CD   1 
ATOM 3272 N NE   . ARG A 1 230 ? 84.722  117.592 111.415 1.00 87.09  ? 230 ARG A NE   1 
ATOM 3273 C CZ   . ARG A 1 230 ? 83.503  117.979 111.767 1.00 88.69  ? 230 ARG A CZ   1 
ATOM 3274 N NH1  . ARG A 1 230 ? 82.761  118.736 110.977 1.00 87.99  ? 230 ARG A NH1  1 
ATOM 3275 N NH2  . ARG A 1 230 ? 83.010  117.586 112.939 1.00 80.95  ? 230 ARG A NH2  1 
ATOM 3276 H H    . ARG A 1 230 ? 86.651  122.304 109.046 1.00 88.33  ? 230 ARG A H    1 
ATOM 3277 H HA   . ARG A 1 230 ? 88.118  120.552 110.417 1.00 89.10  ? 230 ARG A HA   1 
ATOM 3278 H HB2  . ARG A 1 230 ? 86.237  120.220 108.358 1.00 89.65  ? 230 ARG A HB2  1 
ATOM 3279 H HB3  . ARG A 1 230 ? 87.157  119.001 108.781 1.00 89.84  ? 230 ARG A HB3  1 
ATOM 3280 H HG2  . ARG A 1 230 ? 86.101  119.719 111.037 1.00 84.74  ? 230 ARG A HG2  1 
ATOM 3281 H HG3  . ARG A 1 230 ? 84.914  119.978 110.013 1.00 87.10  ? 230 ARG A HG3  1 
ATOM 3282 H HD2  . ARG A 1 230 ? 84.809  117.799 109.441 1.00 86.75  ? 230 ARG A HD2  1 
ATOM 3283 H HD3  . ARG A 1 230 ? 86.216  117.483 110.112 1.00 84.39  ? 230 ARG A HD3  1 
ATOM 3284 H HE   . ARG A 1 230 ? 85.135  117.048 111.937 1.00 82.74  ? 230 ARG A HE   1 
ATOM 3285 H HH11 . ARG A 1 230 ? 83.066  118.998 110.217 1.00 86.93  ? 230 ARG A HH11 1 
ATOM 3286 H HH12 . ARG A 1 230 ? 81.972  118.972 111.226 1.00 87.18  ? 230 ARG A HH12 1 
ATOM 3287 H HH21 . ARG A 1 230 ? 83.483  117.091 113.460 1.00 78.27  ? 230 ARG A HH21 1 
ATOM 3288 H HH22 . ARG A 1 230 ? 82.219  117.827 113.175 1.00 80.18  ? 230 ARG A HH22 1 
ATOM 3289 N N    . PRO A 1 231 ? 88.985  121.085 107.338 1.00 96.02  ? 231 PRO A N    1 
ATOM 3290 C CA   . PRO A 1 231 ? 90.169  120.970 106.467 1.00 93.82  ? 231 PRO A CA   1 
ATOM 3291 C C    . PRO A 1 231 ? 91.354  121.776 106.964 1.00 87.64  ? 231 PRO A C    1 
ATOM 3292 O O    . PRO A 1 231 ? 92.506  121.359 106.782 1.00 82.52  ? 231 PRO A O    1 
ATOM 3293 C CB   . PRO A 1 231 ? 89.664  121.486 105.110 1.00 98.94  ? 231 PRO A CB   1 
ATOM 3294 C CG   . PRO A 1 231 ? 88.178  121.473 105.201 1.00 99.65  ? 231 PRO A CG   1 
ATOM 3295 C CD   . PRO A 1 231 ? 87.857  121.718 106.633 1.00 96.73  ? 231 PRO A CD   1 
ATOM 3296 H HA   . PRO A 1 231 ? 90.428  120.039 106.375 1.00 93.04  ? 231 PRO A HA   1 
ATOM 3297 H HB2  . PRO A 1 231 ? 89.989  122.388 104.962 1.00 95.86  ? 231 PRO A HB2  1 
ATOM 3298 H HB3  . PRO A 1 231 ? 89.966  120.894 104.404 1.00 97.16  ? 231 PRO A HB3  1 
ATOM 3299 H HG2  . PRO A 1 231 ? 87.810  122.176 104.644 1.00 97.52  ? 231 PRO A HG2  1 
ATOM 3300 H HG3  . PRO A 1 231 ? 87.843  120.606 104.922 1.00 97.70  ? 231 PRO A HG3  1 
ATOM 3301 H HD2  . PRO A 1 231 ? 87.831  122.670 106.819 1.00 94.62  ? 231 PRO A HD2  1 
ATOM 3302 H HD3  . PRO A 1 231 ? 87.018  121.293 106.848 1.00 93.73  ? 231 PRO A HD3  1 
ATOM 3303 N N    . LEU A 1 232 ? 91.099  122.928 107.589 1.00 84.03  ? 232 LEU A N    1 
ATOM 3304 C CA   . LEU A 1 232 ? 92.185  123.756 108.098 1.00 79.56  ? 232 LEU A CA   1 
ATOM 3305 C C    . LEU A 1 232 ? 92.972  123.035 109.182 1.00 80.02  ? 232 LEU A C    1 
ATOM 3306 O O    . LEU A 1 232 ? 94.196  123.186 109.266 1.00 79.92  ? 232 LEU A O    1 
ATOM 3307 C CB   . LEU A 1 232 ? 91.618  125.076 108.627 1.00 78.34  ? 232 LEU A CB   1 
ATOM 3308 C CG   . LEU A 1 232 ? 92.442  125.855 109.655 1.00 79.44  ? 232 LEU A CG   1 
ATOM 3309 C CD1  . LEU A 1 232 ? 93.763  126.308 109.055 1.00 80.39  ? 232 LEU A CD1  1 
ATOM 3310 C CD2  . LEU A 1 232 ? 91.649  127.046 110.163 1.00 83.45  ? 232 LEU A CD2  1 
ATOM 3311 H H    . LEU A 1 232 ? 90.312  123.246 107.727 1.00 86.21  ? 232 LEU A H    1 
ATOM 3312 H HA   . LEU A 1 232 ? 92.793  123.962 107.372 1.00 82.14  ? 232 LEU A HA   1 
ATOM 3313 H HB2  . LEU A 1 232 ? 91.483  125.667 107.869 1.00 79.98  ? 232 LEU A HB2  1 
ATOM 3314 H HB3  . LEU A 1 232 ? 90.759  124.889 109.037 1.00 82.02  ? 232 LEU A HB3  1 
ATOM 3315 H HG   . LEU A 1 232 ? 92.634  125.287 110.417 1.00 79.45  ? 232 LEU A HG   1 
ATOM 3316 H HD11 . LEU A 1 232 ? 94.272  126.777 109.734 1.00 80.09  ? 232 LEU A HD11 1 
ATOM 3317 H HD12 . LEU A 1 232 ? 94.256  125.531 108.749 1.00 80.97  ? 232 LEU A HD12 1 
ATOM 3318 H HD13 . LEU A 1 232 ? 93.582  126.899 108.308 1.00 81.78  ? 232 LEU A HD13 1 
ATOM 3319 H HD21 . LEU A 1 232 ? 92.183  127.525 110.815 1.00 82.91  ? 232 LEU A HD21 1 
ATOM 3320 H HD22 . LEU A 1 232 ? 91.439  127.627 109.415 1.00 82.80  ? 232 LEU A HD22 1 
ATOM 3321 H HD23 . LEU A 1 232 ? 90.830  126.727 110.574 1.00 82.57  ? 232 LEU A HD23 1 
ATOM 3322 N N    . VAL A 1 233 ? 92.294  122.254 110.023 1.00 78.88  ? 233 VAL A N    1 
ATOM 3323 C CA   . VAL A 1 233 ? 93.000  121.502 111.054 1.00 77.28  ? 233 VAL A CA   1 
ATOM 3324 C C    . VAL A 1 233 ? 93.638  120.247 110.467 1.00 74.65  ? 233 VAL A C    1 
ATOM 3325 O O    . VAL A 1 233 ? 94.712  119.821 110.916 1.00 75.49  ? 233 VAL A O    1 
ATOM 3326 C CB   . VAL A 1 233 ? 92.042  121.167 112.211 1.00 83.15  ? 233 VAL A CB   1 
ATOM 3327 C CG1  . VAL A 1 233 ? 92.660  120.140 113.138 1.00 83.55  ? 233 VAL A CG1  1 
ATOM 3328 C CG2  . VAL A 1 233 ? 91.680  122.429 112.984 1.00 82.45  ? 233 VAL A CG2  1 
ATOM 3329 H H    . VAL A 1 233 ? 91.441  122.147 110.015 1.00 82.02  ? 233 VAL A H    1 
ATOM 3330 H HA   . VAL A 1 233 ? 93.711  122.057 111.413 1.00 79.75  ? 233 VAL A HA   1 
ATOM 3331 H HB   . VAL A 1 233 ? 91.224  120.793 111.846 1.00 82.32  ? 233 VAL A HB   1 
ATOM 3332 H HG11 . VAL A 1 233 ? 92.664  119.279 112.694 1.00 80.19  ? 233 VAL A HG11 1 
ATOM 3333 H HG12 . VAL A 1 233 ? 93.566  120.409 113.352 1.00 79.39  ? 233 VAL A HG12 1 
ATOM 3334 H HG13 . VAL A 1 233 ? 92.128  120.091 113.948 1.00 80.41  ? 233 VAL A HG13 1 
ATOM 3335 H HG21 . VAL A 1 233 ? 91.070  122.196 113.701 1.00 80.10  ? 233 VAL A HG21 1 
ATOM 3336 H HG22 . VAL A 1 233 ? 92.489  122.817 113.353 1.00 80.12  ? 233 VAL A HG22 1 
ATOM 3337 H HG23 . VAL A 1 233 ? 91.256  123.060 112.382 1.00 83.53  ? 233 VAL A HG23 1 
ATOM 3338 N N    . MET A 1 234 ? 93.009  119.636 109.461 1.00 75.16  ? 234 MET A N    1 
ATOM 3339 C CA   . MET A 1 234 ? 93.611  118.457 108.844 1.00 76.69  ? 234 MET A CA   1 
ATOM 3340 C C    . MET A 1 234 ? 94.924  118.800 108.148 1.00 72.95  ? 234 MET A C    1 
ATOM 3341 O O    . MET A 1 234 ? 95.886  118.021 108.198 1.00 71.37  ? 234 MET A O    1 
ATOM 3342 C CB   . MET A 1 234 ? 92.634  117.819 107.857 1.00 78.40  ? 234 MET A CB   1 
ATOM 3343 C CG   . MET A 1 234 ? 92.853  116.327 107.643 1.00 78.94  ? 234 MET A CG   1 
ATOM 3344 S SD   . MET A 1 234 ? 92.854  115.355 109.165 1.00 89.94  ? 234 MET A SD   1 
ATOM 3345 C CE   . MET A 1 234 ? 91.102  115.100 109.409 1.00 83.53  ? 234 MET A CE   1 
ATOM 3346 H H    . MET A 1 234 ? 92.257  119.879 109.124 1.00 79.61  ? 234 MET A H    1 
ATOM 3347 H HA   . MET A 1 234 ? 93.796  117.819 109.549 1.00 77.92  ? 234 MET A HA   1 
ATOM 3348 H HB2  . MET A 1 234 ? 91.728  117.950 108.179 1.00 80.77  ? 234 MET A HB2  1 
ATOM 3349 H HB3  . MET A 1 234 ? 92.743  118.253 106.997 1.00 79.47  ? 234 MET A HB3  1 
ATOM 3350 H HG2  . MET A 1 234 ? 92.148  115.989 107.067 1.00 79.95  ? 234 MET A HG2  1 
ATOM 3351 H HG3  . MET A 1 234 ? 93.714  116.201 107.216 1.00 79.16  ? 234 MET A HG3  1 
ATOM 3352 H HE1  . MET A 1 234 ? 90.974  114.436 110.106 1.00 81.48  ? 234 MET A HE1  1 
ATOM 3353 H HE2  . MET A 1 234 ? 90.690  115.938 109.670 1.00 83.72  ? 234 MET A HE2  1 
ATOM 3354 H HE3  . MET A 1 234 ? 90.717  114.786 108.576 1.00 84.28  ? 234 MET A HE3  1 
ATOM 3355 N N    . THR A 1 235 ? 94.983  119.951 107.474 1.00 67.46  ? 235 THR A N    1 
ATOM 3356 C CA   . THR A 1 235 ? 96.235  120.329 106.825 1.00 66.78  ? 235 THR A CA   1 
ATOM 3357 C C    . THR A 1 235 ? 97.340  120.576 107.849 1.00 68.16  ? 235 THR A C    1 
ATOM 3358 O O    . THR A 1 235 ? 98.508  120.287 107.576 1.00 68.34  ? 235 THR A O    1 
ATOM 3359 C CB   . THR A 1 235 ? 96.032  121.553 105.927 1.00 71.82  ? 235 THR A CB   1 
ATOM 3360 O OG1  . THR A 1 235 ? 97.270  121.893 105.290 1.00 77.79  ? 235 THR A OG1  1 
ATOM 3361 C CG2  . THR A 1 235 ? 95.520  122.750 106.713 1.00 72.09  ? 235 THR A CG2  1 
ATOM 3362 H H    . THR A 1 235 ? 94.337  120.512 107.378 1.00 72.97  ? 235 THR A H    1 
ATOM 3363 H HA   . THR A 1 235 ? 96.525  119.596 106.257 1.00 68.43  ? 235 THR A HA   1 
ATOM 3364 H HB   . THR A 1 235 ? 95.375  121.338 105.245 1.00 72.69  ? 235 THR A HB   1 
ATOM 3365 H HG1  . THR A 1 235 ? 97.560  121.236 104.853 1.00 76.18  ? 235 THR A HG1  1 
ATOM 3366 H HG21 . THR A 1 235 ? 95.516  123.536 106.144 1.00 72.75  ? 235 THR A HG21 1 
ATOM 3367 H HG22 . THR A 1 235 ? 94.616  122.580 107.014 1.00 76.10  ? 235 THR A HG22 1 
ATOM 3368 H HG23 . THR A 1 235 ? 96.086  122.925 107.480 1.00 73.36  ? 235 THR A HG23 1 
ATOM 3369 N N    . LEU A 1 236 ? 96.997  121.078 109.040 1.00 69.04  ? 236 LEU A N    1 
ATOM 3370 C CA   . LEU A 1 236 ? 97.990  121.181 110.108 1.00 63.34  ? 236 LEU A CA   1 
ATOM 3371 C C    . LEU A 1 236 ? 98.426  119.798 110.584 1.00 61.22  ? 236 LEU A C    1 
ATOM 3372 O O    . LEU A 1 236 ? 99.607  119.573 110.887 1.00 63.93  ? 236 LEU A O    1 
ATOM 3373 C CB   . LEU A 1 236 ? 97.427  121.991 111.278 1.00 57.96  ? 236 LEU A CB   1 
ATOM 3374 C CG   . LEU A 1 236 ? 97.603  123.519 111.327 1.00 63.28  ? 236 LEU A CG   1 
ATOM 3375 C CD1  . LEU A 1 236 ? 99.045  123.957 111.088 1.00 62.69  ? 236 LEU A CD1  1 
ATOM 3376 C CD2  . LEU A 1 236 ? 96.664  124.221 110.353 1.00 69.88  ? 236 LEU A CD2  1 
ATOM 3377 H H    . LEU A 1 236 ? 96.211  121.356 109.251 1.00 70.48  ? 236 LEU A H    1 
ATOM 3378 H HA   . LEU A 1 236 ? 98.774  121.636 109.765 1.00 65.87  ? 236 LEU A HA   1 
ATOM 3379 H HB2  . LEU A 1 236 ? 96.471  121.828 111.307 1.00 65.22  ? 236 LEU A HB2  1 
ATOM 3380 H HB3  . LEU A 1 236 ? 97.828  121.645 112.090 1.00 61.09  ? 236 LEU A HB3  1 
ATOM 3381 H HG   . LEU A 1 236 ? 97.360  123.817 112.217 1.00 65.10  ? 236 LEU A HG   1 
ATOM 3382 H HD11 . LEU A 1 236 ? 99.104  124.917 111.226 1.00 63.40  ? 236 LEU A HD11 1 
ATOM 3383 H HD12 . LEU A 1 236 ? 99.624  123.499 111.716 1.00 61.90  ? 236 LEU A HD12 1 
ATOM 3384 H HD13 . LEU A 1 236 ? 99.298  123.740 110.178 1.00 63.48  ? 236 LEU A HD13 1 
ATOM 3385 H HD21 . LEU A 1 236 ? 96.948  125.143 110.246 1.00 69.29  ? 236 LEU A HD21 1 
ATOM 3386 H HD22 . LEU A 1 236 ? 96.692  123.763 109.499 1.00 69.64  ? 236 LEU A HD22 1 
ATOM 3387 H HD23 . LEU A 1 236 ? 95.766  124.196 110.717 1.00 70.56  ? 236 LEU A HD23 1 
ATOM 3388 N N    . ASN A 1 237 ? 97.477  118.862 110.669 1.00 60.79  ? 237 ASN A N    1 
ATOM 3389 C CA   . ASN A 1 237 ? 97.817  117.496 111.054 1.00 61.62  ? 237 ASN A CA   1 
ATOM 3390 C C    . ASN A 1 237 ? 98.792  116.874 110.066 1.00 63.16  ? 237 ASN A C    1 
ATOM 3391 O O    . ASN A 1 237 ? 99.662  116.089 110.460 1.00 63.60  ? 237 ASN A O    1 
ATOM 3392 C CB   . ASN A 1 237 ? 96.547  116.647 111.146 1.00 68.20  ? 237 ASN A CB   1 
ATOM 3393 C CG   . ASN A 1 237 ? 96.642  115.568 112.204 1.00 75.29  ? 237 ASN A CG   1 
ATOM 3394 O OD1  . ASN A 1 237 ? 96.970  115.844 113.356 1.00 82.97  ? 237 ASN A OD1  1 
ATOM 3395 N ND2  . ASN A 1 237 ? 96.345  114.332 111.818 1.00 75.11  ? 237 ASN A ND2  1 
ATOM 3396 H H    . ASN A 1 237 ? 96.642  118.994 110.509 1.00 66.79  ? 237 ASN A H    1 
ATOM 3397 H HA   . ASN A 1 237 ? 98.238  117.505 111.929 1.00 63.96  ? 237 ASN A HA   1 
ATOM 3398 H HB2  . ASN A 1 237 ? 95.795  117.220 111.371 1.00 69.91  ? 237 ASN A HB2  1 
ATOM 3399 H HB3  . ASN A 1 237 ? 96.392  116.216 110.291 1.00 67.76  ? 237 ASN A HB3  1 
ATOM 3400 H HD21 . ASN A 1 237 ? 96.119  114.180 111.006 1.00 72.67  ? 237 ASN A HD21 1 
ATOM 3401 H HD22 . ASN A 1 237 ? 96.375  113.678 112.374 1.00 72.96  ? 237 ASN A HD22 1 
ATOM 3402 N N    . SER A 1 238 ? 98.660  117.207 108.781 1.00 65.13  ? 238 SER A N    1 
ATOM 3403 C CA   . SER A 1 238 ? 99.624  116.739 107.787 1.00 63.65  ? 238 SER A CA   1 
ATOM 3404 C C    . SER A 1 238 ? 100.946 117.493 107.873 1.00 59.32  ? 238 SER A C    1 
ATOM 3405 O O    . SER A 1 238 ? 102.017 116.904 107.665 1.00 58.79  ? 238 SER A O    1 
ATOM 3406 C CB   . SER A 1 238 ? 99.045  116.889 106.380 1.00 63.15  ? 238 SER A CB   1 
ATOM 3407 O OG   . SER A 1 238 ? 99.729  116.056 105.462 1.00 64.09  ? 238 SER A OG   1 
ATOM 3408 H H    . SER A 1 238 ? 98.030  117.698 108.459 1.00 65.23  ? 238 SER A H    1 
ATOM 3409 H HA   . SER A 1 238 ? 99.804  115.797 107.939 1.00 63.09  ? 238 SER A HA   1 
ATOM 3410 H HB2  . SER A 1 238 ? 98.107  116.647 106.392 1.00 63.82  ? 238 SER A HB2  1 
ATOM 3411 H HB3  . SER A 1 238 ? 99.146  117.810 106.097 1.00 64.99  ? 238 SER A HB3  1 
ATOM 3412 H HG   . SER A 1 238 ? 99.865  115.304 105.808 1.00 62.69  ? 238 SER A HG   1 
ATOM 3413 N N    . LEU A 1 239 ? 100.891 118.790 108.172 1.00 56.45  ? 239 LEU A N    1 
ATOM 3414 C CA   . LEU A 1 239 ? 102.109 119.587 108.254 1.00 54.53  ? 239 LEU A CA   1 
ATOM 3415 C C    . LEU A 1 239 ? 102.995 119.125 109.404 1.00 59.39  ? 239 LEU A C    1 
ATOM 3416 O O    . LEU A 1 239 ? 104.227 119.212 109.315 1.00 61.80  ? 239 LEU A O    1 
ATOM 3417 C CB   . LEU A 1 239 ? 101.738 121.065 108.405 1.00 54.63  ? 239 LEU A CB   1 
ATOM 3418 C CG   . LEU A 1 239 ? 101.766 121.914 107.130 1.00 53.55  ? 239 LEU A CG   1 
ATOM 3419 C CD1  . LEU A 1 239 ? 103.179 122.337 106.862 1.00 55.46  ? 239 LEU A CD1  1 
ATOM 3420 C CD2  . LEU A 1 239 ? 101.181 121.188 105.917 1.00 56.51  ? 239 LEU A CD2  1 
ATOM 3421 H H    . LEU A 1 239 ? 100.166 119.226 108.329 1.00 60.68  ? 239 LEU A H    1 
ATOM 3422 H HA   . LEU A 1 239 ? 102.613 119.483 107.434 1.00 55.85  ? 239 LEU A HA   1 
ATOM 3423 H HB2  . LEU A 1 239 ? 100.833 121.117 108.752 1.00 58.60  ? 239 LEU A HB2  1 
ATOM 3424 H HB3  . LEU A 1 239 ? 102.347 121.473 109.038 1.00 55.57  ? 239 LEU A HB3  1 
ATOM 3425 H HG   . LEU A 1 239 ? 101.239 122.717 107.271 1.00 57.25  ? 239 LEU A HG   1 
ATOM 3426 H HD11 . LEU A 1 239 ? 103.214 122.835 106.030 1.00 55.26  ? 239 LEU A HD11 1 
ATOM 3427 H HD12 . LEU A 1 239 ? 103.490 122.888 107.597 1.00 58.56  ? 239 LEU A HD12 1 
ATOM 3428 H HD13 . LEU A 1 239 ? 103.721 121.536 106.795 1.00 56.11  ? 239 LEU A HD13 1 
ATOM 3429 H HD21 . LEU A 1 239 ? 101.169 121.799 105.164 1.00 56.12  ? 239 LEU A HD21 1 
ATOM 3430 H HD22 . LEU A 1 239 ? 101.728 120.417 105.701 1.00 56.92  ? 239 LEU A HD22 1 
ATOM 3431 H HD23 . LEU A 1 239 ? 100.277 120.905 106.122 1.00 57.25  ? 239 LEU A HD23 1 
ATOM 3432 N N    . GLY A 1 240 ? 102.391 118.624 110.482 1.00 56.99  ? 240 GLY A N    1 
ATOM 3433 C CA   . GLY A 1 240 ? 103.189 118.026 111.542 1.00 53.76  ? 240 GLY A CA   1 
ATOM 3434 C C    . GLY A 1 240 ? 103.983 116.822 111.064 1.00 56.29  ? 240 GLY A C    1 
ATOM 3435 O O    . GLY A 1 240 ? 105.182 116.697 111.345 1.00 62.44  ? 240 GLY A O    1 
ATOM 3436 H H    . GLY A 1 240 ? 101.544 118.621 110.619 1.00 58.79  ? 240 GLY A H    1 
ATOM 3437 H HA2  . GLY A 1 240 ? 103.811 118.686 111.885 1.00 56.99  ? 240 GLY A HA2  1 
ATOM 3438 H HA3  . GLY A 1 240 ? 102.607 117.744 112.266 1.00 56.63  ? 240 GLY A HA3  1 
ATOM 3439 N N    . PHE A 1 241 ? 103.332 115.926 110.318 1.00 58.83  ? 241 PHE A N    1 
ATOM 3440 C CA   . PHE A 1 241 ? 104.043 114.777 109.772 1.00 58.30  ? 241 PHE A CA   1 
ATOM 3441 C C    . PHE A 1 241 ? 105.133 115.216 108.810 1.00 60.14  ? 241 PHE A C    1 
ATOM 3442 O O    . PHE A 1 241 ? 106.169 114.550 108.702 1.00 57.90  ? 241 PHE A O    1 
ATOM 3443 C CB   . PHE A 1 241 ? 103.069 113.836 109.064 1.00 59.90  ? 241 PHE A CB   1 
ATOM 3444 C CG   . PHE A 1 241 ? 103.686 112.533 108.641 1.00 66.81  ? 241 PHE A CG   1 
ATOM 3445 C CD1  . PHE A 1 241 ? 104.396 112.439 107.457 1.00 71.81  ? 241 PHE A CD1  1 
ATOM 3446 C CD2  . PHE A 1 241 ? 103.560 111.402 109.430 1.00 74.97  ? 241 PHE A CD2  1 
ATOM 3447 C CE1  . PHE A 1 241 ? 104.966 111.243 107.068 1.00 76.59  ? 241 PHE A CE1  1 
ATOM 3448 C CE2  . PHE A 1 241 ? 104.127 110.202 109.045 1.00 78.75  ? 241 PHE A CE2  1 
ATOM 3449 C CZ   . PHE A 1 241 ? 104.831 110.124 107.862 1.00 75.33  ? 241 PHE A CZ   1 
ATOM 3450 H H    . PHE A 1 241 ? 102.495 115.960 110.119 1.00 59.78  ? 241 PHE A H    1 
ATOM 3451 H HA   . PHE A 1 241 ? 104.459 114.287 110.499 1.00 60.79  ? 241 PHE A HA   1 
ATOM 3452 H HB2  . PHE A 1 241 ? 102.331 113.637 109.661 1.00 62.00  ? 241 PHE A HB2  1 
ATOM 3453 H HB3  . PHE A 1 241 ? 102.734 114.276 108.265 1.00 60.87  ? 241 PHE A HB3  1 
ATOM 3454 H HD1  . PHE A 1 241 ? 104.489 113.192 106.918 1.00 68.31  ? 241 PHE A HD1  1 
ATOM 3455 H HD2  . PHE A 1 241 ? 103.087 111.450 110.229 1.00 69.06  ? 241 PHE A HD2  1 
ATOM 3456 H HE1  . PHE A 1 241 ? 105.439 111.193 106.270 1.00 73.87  ? 241 PHE A HE1  1 
ATOM 3457 H HE2  . PHE A 1 241 ? 104.035 109.450 109.584 1.00 72.20  ? 241 PHE A HE2  1 
ATOM 3458 H HZ   . PHE A 1 241 ? 105.215 109.318 107.599 1.00 71.65  ? 241 PHE A HZ   1 
ATOM 3459 N N    . SER A 1 242 ? 104.916 116.325 108.102 1.00 63.50  ? 242 SER A N    1 
ATOM 3460 C CA   . SER A 1 242 ? 105.959 116.835 107.216 1.00 58.96  ? 242 SER A CA   1 
ATOM 3461 C C    . SER A 1 242 ? 107.150 117.383 107.993 1.00 57.57  ? 242 SER A C    1 
ATOM 3462 O O    . SER A 1 242 ? 108.296 117.188 107.576 1.00 57.30  ? 242 SER A O    1 
ATOM 3463 C CB   . SER A 1 242 ? 105.383 117.917 106.301 1.00 61.48  ? 242 SER A CB   1 
ATOM 3464 O OG   . SER A 1 242 ? 105.018 117.365 105.051 1.00 66.39  ? 242 SER A OG   1 
ATOM 3465 H H    . SER A 1 242 ? 104.190 116.786 108.114 1.00 61.53  ? 242 SER A H    1 
ATOM 3466 H HA   . SER A 1 242 ? 106.281 116.112 106.658 1.00 59.95  ? 242 SER A HA   1 
ATOM 3467 H HB2  . SER A 1 242 ? 104.592 118.291 106.715 1.00 60.79  ? 242 SER A HB2  1 
ATOM 3468 H HB3  . SER A 1 242 ? 106.045 118.610 106.168 1.00 59.59  ? 242 SER A HB3  1 
ATOM 3469 H HG   . SER A 1 242 ? 105.496 116.697 104.877 1.00 64.06  ? 242 SER A HG   1 
ATOM 3470 N N    . PHE A 1 243 ? 106.909 118.062 109.119 1.00 56.75  ? 243 PHE A N    1 
ATOM 3471 C CA   . PHE A 1 243 ? 108.018 118.527 109.951 1.00 52.08  ? 243 PHE A CA   1 
ATOM 3472 C C    . PHE A 1 243 ? 108.740 117.362 110.618 1.00 48.53  ? 243 PHE A C    1 
ATOM 3473 O O    . PHE A 1 243 ? 109.907 117.504 111.021 1.00 47.00  ? 243 PHE A O    1 
ATOM 3474 C CB   . PHE A 1 243 ? 107.499 119.527 110.997 1.00 55.64  ? 243 PHE A CB   1 
ATOM 3475 C CG   . PHE A 1 243 ? 108.460 119.800 112.135 1.00 61.33  ? 243 PHE A CG   1 
ATOM 3476 C CD1  . PHE A 1 243 ? 109.084 121.031 112.236 1.00 59.36  ? 243 PHE A CD1  1 
ATOM 3477 C CD2  . PHE A 1 243 ? 108.689 118.861 113.132 1.00 65.59  ? 243 PHE A CD2  1 
ATOM 3478 C CE1  . PHE A 1 243 ? 109.955 121.302 113.277 1.00 55.83  ? 243 PHE A CE1  1 
ATOM 3479 C CE2  . PHE A 1 243 ? 109.561 119.125 114.170 1.00 71.67  ? 243 PHE A CE2  1 
ATOM 3480 C CZ   . PHE A 1 243 ? 110.189 120.348 114.246 1.00 64.87  ? 243 PHE A CZ   1 
ATOM 3481 H H    . PHE A 1 243 ? 106.128 118.262 109.416 1.00 57.68  ? 243 PHE A H    1 
ATOM 3482 H HA   . PHE A 1 243 ? 108.659 118.990 109.390 1.00 55.35  ? 243 PHE A HA   1 
ATOM 3483 H HB2  . PHE A 1 243 ? 107.317 120.372 110.557 1.00 56.24  ? 243 PHE A HB2  1 
ATOM 3484 H HB3  . PHE A 1 243 ? 106.680 119.179 111.381 1.00 58.97  ? 243 PHE A HB3  1 
ATOM 3485 H HD1  . PHE A 1 243 ? 108.936 121.676 111.583 1.00 59.01  ? 243 PHE A HD1  1 
ATOM 3486 H HD2  . PHE A 1 243 ? 108.275 118.029 113.084 1.00 62.47  ? 243 PHE A HD2  1 
ATOM 3487 H HE1  . PHE A 1 243 ? 110.378 122.128 113.327 1.00 56.83  ? 243 PHE A HE1  1 
ATOM 3488 H HE2  . PHE A 1 243 ? 109.714 118.480 114.823 1.00 68.31  ? 243 PHE A HE2  1 
ATOM 3489 H HZ   . PHE A 1 243 ? 110.771 120.530 114.948 1.00 64.44  ? 243 PHE A HZ   1 
ATOM 3490 N N    . GLY A 1 244 ? 108.064 116.223 110.749 1.00 50.40  ? 244 GLY A N    1 
ATOM 3491 C CA   . GLY A 1 244 ? 108.729 115.045 111.273 1.00 53.46  ? 244 GLY A CA   1 
ATOM 3492 C C    . GLY A 1 244 ? 110.025 114.729 110.552 1.00 51.47  ? 244 GLY A C    1 
ATOM 3493 O O    . GLY A 1 244 ? 110.963 114.208 111.157 1.00 54.79  ? 244 GLY A O    1 
ATOM 3494 H H    . GLY A 1 244 ? 107.236 116.111 110.546 1.00 55.12  ? 244 GLY A H    1 
ATOM 3495 H HA2  . GLY A 1 244 ? 108.927 115.179 112.213 1.00 55.21  ? 244 GLY A HA2  1 
ATOM 3496 H HA3  . GLY A 1 244 ? 108.138 114.280 111.192 1.00 55.98  ? 244 GLY A HA3  1 
ATOM 3497 N N    . HIS A 1 245 ? 110.101 115.038 109.254 1.00 51.72  ? 245 HIS A N    1 
ATOM 3498 C CA   . HIS A 1 245 ? 111.330 114.787 108.506 1.00 50.41  ? 245 HIS A CA   1 
ATOM 3499 C C    . HIS A 1 245 ? 112.478 115.651 109.015 1.00 46.98  ? 245 HIS A C    1 
ATOM 3500 O O    . HIS A 1 245 ? 113.603 115.164 109.183 1.00 51.83  ? 245 HIS A O    1 
ATOM 3501 C CB   . HIS A 1 245 ? 111.100 115.042 107.017 1.00 50.54  ? 245 HIS A CB   1 
ATOM 3502 C CG   . HIS A 1 245 ? 110.175 114.059 106.372 1.00 52.62  ? 245 HIS A CG   1 
ATOM 3503 N ND1  . HIS A 1 245 ? 110.065 112.752 106.793 1.00 61.03  ? 245 HIS A ND1  1 
ATOM 3504 C CD2  . HIS A 1 245 ? 109.315 114.194 105.336 1.00 55.22  ? 245 HIS A CD2  1 
ATOM 3505 C CE1  . HIS A 1 245 ? 109.177 112.124 106.044 1.00 64.08  ? 245 HIS A CE1  1 
ATOM 3506 N NE2  . HIS A 1 245 ? 108.707 112.976 105.152 1.00 64.44  ? 245 HIS A NE2  1 
ATOM 3507 H H    . HIS A 1 245 ? 109.465 115.388 108.793 1.00 53.74  ? 245 HIS A H    1 
ATOM 3508 H HA   . HIS A 1 245 ? 111.584 113.858 108.618 1.00 52.05  ? 245 HIS A HA   1 
ATOM 3509 H HB2  . HIS A 1 245 ? 110.717 115.926 106.908 1.00 53.50  ? 245 HIS A HB2  1 
ATOM 3510 H HB3  . HIS A 1 245 ? 111.952 114.994 106.557 1.00 51.86  ? 245 HIS A HB3  1 
ATOM 3511 H HD1  . HIS A 1 245 ? 110.505 112.400 107.443 1.00 59.26  ? 245 HIS A HD1  1 
ATOM 3512 H HD2  . HIS A 1 245 ? 109.164 114.966 104.841 1.00 56.71  ? 245 HIS A HD2  1 
ATOM 3513 H HE1  . HIS A 1 245 ? 108.925 111.233 106.130 1.00 63.99  ? 245 HIS A HE1  1 
ATOM 3514 N N    . VAL A 1 246 ? 112.219 116.940 109.252 1.00 41.83  ? 246 VAL A N    1 
ATOM 3515 C CA   . VAL A 1 246 ? 113.258 117.809 109.797 1.00 43.93  ? 246 VAL A CA   1 
ATOM 3516 C C    . VAL A 1 246 ? 113.674 117.321 111.175 1.00 54.50  ? 246 VAL A C    1 
ATOM 3517 O O    . VAL A 1 246 ? 114.861 117.333 111.523 1.00 55.00  ? 246 VAL A O    1 
ATOM 3518 C CB   . VAL A 1 246 ? 112.775 119.270 109.839 1.00 48.78  ? 246 VAL A CB   1 
ATOM 3519 C CG1  . VAL A 1 246 ? 113.785 120.141 110.574 1.00 45.95  ? 246 VAL A CG1  1 
ATOM 3520 C CG2  . VAL A 1 246 ? 112.544 119.795 108.433 1.00 46.93  ? 246 VAL A CG2  1 
ATOM 3521 H H    . VAL A 1 246 ? 111.465 117.327 109.108 1.00 47.17  ? 246 VAL A H    1 
ATOM 3522 H HA   . VAL A 1 246 ? 114.036 117.769 109.219 1.00 44.79  ? 246 VAL A HA   1 
ATOM 3523 H HB   . VAL A 1 246 ? 111.934 119.313 110.320 1.00 51.36  ? 246 VAL A HB   1 
ATOM 3524 H HG11 . VAL A 1 246 ? 114.660 119.724 110.529 1.00 44.80  ? 246 VAL A HG11 1 
ATOM 3525 H HG12 . VAL A 1 246 ? 113.815 121.013 110.151 1.00 50.16  ? 246 VAL A HG12 1 
ATOM 3526 H HG13 . VAL A 1 246 ? 113.507 120.234 111.499 1.00 48.42  ? 246 VAL A HG13 1 
ATOM 3527 H HG21 . VAL A 1 246 ? 112.250 120.718 108.485 1.00 49.22  ? 246 VAL A HG21 1 
ATOM 3528 H HG22 . VAL A 1 246 ? 113.374 119.739 107.935 1.00 46.98  ? 246 VAL A HG22 1 
ATOM 3529 H HG23 . VAL A 1 246 ? 111.862 119.255 108.004 1.00 48.05  ? 246 VAL A HG23 1 
ATOM 3530 N N    . LEU A 1 247 ? 112.705 116.889 111.984 1.00 62.57  ? 247 LEU A N    1 
ATOM 3531 C CA   . LEU A 1 247 ? 113.059 116.358 113.299 1.00 52.84  ? 247 LEU A CA   1 
ATOM 3532 C C    . LEU A 1 247 ? 113.964 115.137 113.166 1.00 53.38  ? 247 LEU A C    1 
ATOM 3533 O O    . LEU A 1 247 ? 114.969 115.013 113.879 1.00 50.50  ? 247 LEU A O    1 
ATOM 3534 C CB   . LEU A 1 247 ? 111.800 116.001 114.088 1.00 50.47  ? 247 LEU A CB   1 
ATOM 3535 C CG   . LEU A 1 247 ? 112.056 115.347 115.450 1.00 55.71  ? 247 LEU A CG   1 
ATOM 3536 C CD1  . LEU A 1 247 ? 113.120 116.107 116.233 1.00 55.59  ? 247 LEU A CD1  1 
ATOM 3537 C CD2  . LEU A 1 247 ? 110.773 115.245 116.254 1.00 64.82  ? 247 LEU A CD2  1 
ATOM 3538 H H    . LEU A 1 247 ? 111.864 116.895 111.805 1.00 55.47  ? 247 LEU A H    1 
ATOM 3539 H HA   . LEU A 1 247 ? 113.544 117.039 113.789 1.00 52.02  ? 247 LEU A HA   1 
ATOM 3540 H HB2  . LEU A 1 247 ? 111.293 116.813 114.245 1.00 53.58  ? 247 LEU A HB2  1 
ATOM 3541 H HB3  . LEU A 1 247 ? 111.270 115.383 113.562 1.00 52.42  ? 247 LEU A HB3  1 
ATOM 3542 H HG   . LEU A 1 247 ? 112.384 114.446 115.306 1.00 55.90  ? 247 LEU A HG   1 
ATOM 3543 H HD11 . LEU A 1 247 ? 113.996 115.882 115.883 1.00 53.48  ? 247 LEU A HD11 1 
ATOM 3544 H HD12 . LEU A 1 247 ? 112.962 117.060 116.139 1.00 56.58  ? 247 LEU A HD12 1 
ATOM 3545 H HD13 . LEU A 1 247 ? 113.066 115.853 117.168 1.00 57.53  ? 247 LEU A HD13 1 
ATOM 3546 H HD21 . LEU A 1 247 ? 110.881 114.556 116.928 1.00 61.17  ? 247 LEU A HD21 1 
ATOM 3547 H HD22 . LEU A 1 247 ? 110.598 116.099 116.679 1.00 64.52  ? 247 LEU A HD22 1 
ATOM 3548 H HD23 . LEU A 1 247 ? 110.044 115.013 115.658 1.00 61.93  ? 247 LEU A HD23 1 
ATOM 3549 N N    . MET A 1 248 ? 113.626 114.229 112.247 1.00 58.13  ? 248 MET A N    1 
ATOM 3550 C CA   . MET A 1 248 ? 114.442 113.038 112.037 1.00 54.87  ? 248 MET A CA   1 
ATOM 3551 C C    . MET A 1 248 ? 115.854 113.417 111.620 1.00 49.03  ? 248 MET A C    1 
ATOM 3552 O O    . MET A 1 248 ? 116.833 112.852 112.120 1.00 49.49  ? 248 MET A O    1 
ATOM 3553 C CB   . MET A 1 248 ? 113.797 112.147 110.974 1.00 58.01  ? 248 MET A CB   1 
ATOM 3554 C CG   . MET A 1 248 ? 114.569 110.872 110.660 1.00 64.50  ? 248 MET A CG   1 
ATOM 3555 S SD   . MET A 1 248 ? 114.299 109.619 111.924 1.00 79.00  ? 248 MET A SD   1 
ATOM 3556 C CE   . MET A 1 248 ? 115.902 108.833 112.008 1.00 55.79  ? 248 MET A CE   1 
ATOM 3557 H H    . MET A 1 248 ? 112.935 114.281 111.738 1.00 55.66  ? 248 MET A H    1 
ATOM 3558 H HA   . MET A 1 248 ? 114.483 112.536 112.865 1.00 55.27  ? 248 MET A HA   1 
ATOM 3559 H HB2  . MET A 1 248 ? 112.912 111.889 111.278 1.00 57.33  ? 248 MET A HB2  1 
ATOM 3560 H HB3  . MET A 1 248 ? 113.725 112.656 110.153 1.00 56.55  ? 248 MET A HB3  1 
ATOM 3561 H HG2  . MET A 1 248 ? 114.260 110.517 109.812 1.00 62.95  ? 248 MET A HG2  1 
ATOM 3562 H HG3  . MET A 1 248 ? 115.519 111.058 110.615 1.00 61.73  ? 248 MET A HG3  1 
ATOM 3563 H HE1  . MET A 1 248 ? 115.944 108.300 112.817 1.00 57.49  ? 248 MET A HE1  1 
ATOM 3564 H HE2  . MET A 1 248 ? 116.014 108.263 111.235 1.00 55.35  ? 248 MET A HE2  1 
ATOM 3565 H HE3  . MET A 1 248 ? 116.590 109.516 112.024 1.00 59.39  ? 248 MET A HE3  1 
ATOM 3566 N N    . ALA A 1 249 ? 115.979 114.373 110.698 1.00 48.41  ? 249 ALA A N    1 
ATOM 3567 C CA   . ALA A 1 249 ? 117.302 114.797 110.258 1.00 49.62  ? 249 ALA A CA   1 
ATOM 3568 C C    . ALA A 1 249 ? 118.090 115.423 111.398 1.00 41.57  ? 249 ALA A C    1 
ATOM 3569 O O    . ALA A 1 249 ? 119.311 115.247 111.480 1.00 40.19  ? 249 ALA A O    1 
ATOM 3570 C CB   . ALA A 1 249 ? 117.182 115.785 109.100 1.00 56.26  ? 249 ALA A CB   1 
ATOM 3571 H H    . ALA A 1 249 ? 115.324 114.782 110.320 1.00 51.24  ? 249 ALA A H    1 
ATOM 3572 H HA   . ALA A 1 249 ? 117.794 114.023 109.943 1.00 49.57  ? 249 ALA A HA   1 
ATOM 3573 H HB1  . ALA A 1 249 ? 116.716 116.578 109.408 1.00 54.84  ? 249 ALA A HB1  1 
ATOM 3574 H HB2  . ALA A 1 249 ? 118.072 116.019 108.798 1.00 53.82  ? 249 ALA A HB2  1 
ATOM 3575 H HB3  . ALA A 1 249 ? 116.687 115.368 108.379 1.00 54.16  ? 249 ALA A HB3  1 
ATOM 3576 N N    . ALA A 1 250 ? 117.414 116.154 112.286 1.00 44.11  ? 250 ALA A N    1 
ATOM 3577 C CA   . ALA A 1 250 ? 118.112 116.805 113.388 1.00 46.57  ? 250 ALA A CA   1 
ATOM 3578 C C    . ALA A 1 250 ? 118.556 115.805 114.447 1.00 52.18  ? 250 ALA A C    1 
ATOM 3579 O O    . ALA A 1 250 ? 119.590 116.010 115.093 1.00 43.85  ? 250 ALA A O    1 
ATOM 3580 C CB   . ALA A 1 250 ? 117.219 117.873 114.017 1.00 51.67  ? 250 ALA A CB   1 
ATOM 3581 H H    . ALA A 1 250 ? 116.564 116.286 112.271 1.00 47.97  ? 250 ALA A H    1 
ATOM 3582 H HA   . ALA A 1 250 ? 118.905 117.245 113.042 1.00 44.90  ? 250 ALA A HA   1 
ATOM 3583 H HB1  . ALA A 1 250 ? 117.698 118.296 114.746 1.00 50.17  ? 250 ALA A HB1  1 
ATOM 3584 H HB2  . ALA A 1 250 ? 116.993 118.532 113.342 1.00 50.46  ? 250 ALA A HB2  1 
ATOM 3585 H HB3  . ALA A 1 250 ? 116.411 117.452 114.352 1.00 51.66  ? 250 ALA A HB3  1 
ATOM 3586 N N    . VAL A 1 251 ? 117.799 114.726 114.644 1.00 56.36  ? 251 VAL A N    1 
ATOM 3587 C CA   . VAL A 1 251 ? 118.142 113.766 115.691 1.00 47.75  ? 251 VAL A CA   1 
ATOM 3588 C C    . VAL A 1 251 ? 119.295 112.871 115.251 1.00 47.15  ? 251 VAL A C    1 
ATOM 3589 O O    . VAL A 1 251 ? 120.262 112.672 115.995 1.00 44.87  ? 251 VAL A O    1 
ATOM 3590 C CB   . VAL A 1 251 ? 116.902 112.940 116.082 1.00 46.87  ? 251 VAL A CB   1 
ATOM 3591 C CG1  . VAL A 1 251 ? 117.306 111.564 116.599 1.00 43.01  ? 251 VAL A CG1  1 
ATOM 3592 C CG2  . VAL A 1 251 ? 116.080 113.681 117.124 1.00 54.14  ? 251 VAL A CG2  1 
ATOM 3593 H H    . VAL A 1 251 ? 117.093 114.529 114.193 1.00 51.98  ? 251 VAL A H    1 
ATOM 3594 H HA   . VAL A 1 251 ? 118.436 114.254 116.476 1.00 47.21  ? 251 VAL A HA   1 
ATOM 3595 H HB   . VAL A 1 251 ? 116.347 112.813 115.297 1.00 49.63  ? 251 VAL A HB   1 
ATOM 3596 H HG11 . VAL A 1 251 ? 116.542 111.164 117.044 1.00 45.60  ? 251 VAL A HG11 1 
ATOM 3597 H HG12 . VAL A 1 251 ? 117.577 111.005 115.854 1.00 43.84  ? 251 VAL A HG12 1 
ATOM 3598 H HG13 . VAL A 1 251 ? 118.035 111.661 117.231 1.00 44.04  ? 251 VAL A HG13 1 
ATOM 3599 H HG21 . VAL A 1 251 ? 116.365 114.607 117.156 1.00 52.14  ? 251 VAL A HG21 1 
ATOM 3600 H HG22 . VAL A 1 251 ? 115.143 113.634 116.876 1.00 54.84  ? 251 VAL A HG22 1 
ATOM 3601 H HG23 . VAL A 1 251 ? 116.214 113.262 117.988 1.00 52.03  ? 251 VAL A HG23 1 
ATOM 3602 N N    . ALA A 1 252 ? 119.212 112.316 114.039 1.00 52.24  ? 252 ALA A N    1 
ATOM 3603 C CA   . ALA A 1 252 ? 120.215 111.350 113.600 1.00 47.25  ? 252 ALA A CA   1 
ATOM 3604 C C    . ALA A 1 252 ? 121.614 111.950 113.585 1.00 42.85  ? 252 ALA A C    1 
ATOM 3605 O O    . ALA A 1 252 ? 122.595 111.242 113.837 1.00 44.19  ? 252 ALA A O    1 
ATOM 3606 C CB   . ALA A 1 252 ? 119.857 110.817 112.213 1.00 49.43  ? 252 ALA A CB   1 
ATOM 3607 H H    . ALA A 1 252 ? 118.596 112.480 113.463 1.00 50.69  ? 252 ALA A H    1 
ATOM 3608 H HA   . ALA A 1 252 ? 120.220 110.601 114.215 1.00 47.98  ? 252 ALA A HA   1 
ATOM 3609 H HB1  . ALA A 1 252 ? 119.832 111.557 111.587 1.00 50.77  ? 252 ALA A HB1  1 
ATOM 3610 H HB2  . ALA A 1 252 ? 120.531 110.175 111.940 1.00 48.70  ? 252 ALA A HB2  1 
ATOM 3611 H HB3  . ALA A 1 252 ? 118.988 110.388 112.255 1.00 52.04  ? 252 ALA A HB3  1 
ATOM 3612 N N    . TYR A 1 253 ? 121.730 113.245 113.288 1.00 41.11  ? 253 TYR A N    1 
ATOM 3613 C CA   . TYR A 1 253 ? 123.041 113.879 113.235 1.00 40.81  ? 253 TYR A CA   1 
ATOM 3614 C C    . TYR A 1 253 ? 123.730 113.888 114.594 1.00 37.53  ? 253 TYR A C    1 
ATOM 3615 O O    . TYR A 1 253 ? 124.955 114.040 114.654 1.00 36.56  ? 253 TYR A O    1 
ATOM 3616 C CB   . TYR A 1 253 ? 122.897 115.306 112.697 1.00 43.33  ? 253 TYR A CB   1 
ATOM 3617 C CG   . TYR A 1 253 ? 124.202 116.042 112.494 1.00 37.17  ? 253 TYR A CG   1 
ATOM 3618 C CD1  . TYR A 1 253 ? 124.785 116.764 113.526 1.00 43.66  ? 253 TYR A CD1  1 
ATOM 3619 C CD2  . TYR A 1 253 ? 124.849 116.020 111.266 1.00 33.13  ? 253 TYR A CD2  1 
ATOM 3620 C CE1  . TYR A 1 253 ? 125.975 117.440 113.342 1.00 39.10  ? 253 TYR A CE1  1 
ATOM 3621 C CE2  . TYR A 1 253 ? 126.040 116.693 111.073 1.00 34.57  ? 253 TYR A CE2  1 
ATOM 3622 C CZ   . TYR A 1 253 ? 126.598 117.401 112.114 1.00 36.80  ? 253 TYR A CZ   1 
ATOM 3623 O OH   . TYR A 1 253 ? 127.785 118.072 111.928 1.00 48.73  ? 253 TYR A OH   1 
ATOM 3624 H H    . TYR A 1 253 ? 121.072 113.771 113.117 1.00 43.20  ? 253 TYR A H    1 
ATOM 3625 H HA   . TYR A 1 253 ? 123.605 113.384 112.620 1.00 40.42  ? 253 TYR A HA   1 
ATOM 3626 H HB2  . TYR A 1 253 ? 122.446 115.268 111.839 1.00 42.03  ? 253 TYR A HB2  1 
ATOM 3627 H HB3  . TYR A 1 253 ? 122.365 115.820 113.323 1.00 43.38  ? 253 TYR A HB3  1 
ATOM 3628 H HD1  . TYR A 1 253 ? 124.367 116.792 114.356 1.00 42.96  ? 253 TYR A HD1  1 
ATOM 3629 H HD2  . TYR A 1 253 ? 124.474 115.543 110.561 1.00 35.35  ? 253 TYR A HD2  1 
ATOM 3630 H HE1  . TYR A 1 253 ? 126.354 117.918 114.044 1.00 40.38  ? 253 TYR A HE1  1 
ATOM 3631 H HE2  . TYR A 1 253 ? 126.463 116.668 110.245 1.00 36.68  ? 253 TYR A HE2  1 
ATOM 3632 H HH   . TYR A 1 253 ? 128.051 117.972 111.137 1.00 44.68  ? 253 TYR A HH   1 
ATOM 3633 N N    . GLY A 1 254 ? 122.980 113.717 115.679 1.00 39.17  ? 254 GLY A N    1 
ATOM 3634 C CA   . GLY A 1 254 ? 123.557 113.754 117.008 1.00 44.30  ? 254 GLY A CA   1 
ATOM 3635 C C    . GLY A 1 254 ? 124.071 112.411 117.484 1.00 47.47  ? 254 GLY A C    1 
ATOM 3636 O O    . GLY A 1 254 ? 125.242 112.287 117.857 1.00 50.18  ? 254 GLY A O    1 
ATOM 3637 H H    . GLY A 1 254 ? 122.131 113.578 115.668 1.00 42.29  ? 254 GLY A H    1 
ATOM 3638 H HA2  . GLY A 1 254 ? 124.295 114.382 117.020 1.00 43.04  ? 254 GLY A HA2  1 
ATOM 3639 H HA3  . GLY A 1 254 ? 122.887 114.061 117.638 1.00 44.52  ? 254 GLY A HA3  1 
ATOM 3640 N N    . VAL A 1 255 ? 123.210 111.397 117.474 1.00 42.07  ? 255 VAL A N    1 
ATOM 3641 C CA   . VAL A 1 255 ? 123.554 110.061 117.948 1.00 37.18  ? 255 VAL A CA   1 
ATOM 3642 C C    . VAL A 1 255 ? 123.834 109.176 116.743 1.00 40.92  ? 255 VAL A C    1 
ATOM 3643 O O    . VAL A 1 255 ? 123.036 109.123 115.799 1.00 47.81  ? 255 VAL A O    1 
ATOM 3644 C CB   . VAL A 1 255 ? 122.433 109.474 118.824 1.00 40.72  ? 255 VAL A CB   1 
ATOM 3645 C CG1  . VAL A 1 255 ? 121.909 110.526 119.790 1.00 42.93  ? 255 VAL A CG1  1 
ATOM 3646 C CG2  . VAL A 1 255 ? 121.300 108.921 117.971 1.00 40.97  ? 255 VAL A CG2  1 
ATOM 3647 H H    . VAL A 1 255 ? 122.400 111.461 117.192 1.00 42.31  ? 255 VAL A H    1 
ATOM 3648 H HA   . VAL A 1 255 ? 124.362 110.108 118.483 1.00 39.78  ? 255 VAL A HA   1 
ATOM 3649 H HB   . VAL A 1 255 ? 122.796 108.742 119.348 1.00 42.13  ? 255 VAL A HB   1 
ATOM 3650 H HG11 . VAL A 1 255 ? 121.295 110.104 120.411 1.00 41.64  ? 255 VAL A HG11 1 
ATOM 3651 H HG12 . VAL A 1 255 ? 122.657 110.910 120.274 1.00 43.61  ? 255 VAL A HG12 1 
ATOM 3652 H HG13 . VAL A 1 255 ? 121.448 111.217 119.289 1.00 43.27  ? 255 VAL A HG13 1 
ATOM 3653 H HG21 . VAL A 1 255 ? 120.520 108.795 118.533 1.00 39.50  ? 255 VAL A HG21 1 
ATOM 3654 H HG22 . VAL A 1 255 ? 121.100 109.552 117.263 1.00 41.49  ? 255 VAL A HG22 1 
ATOM 3655 H HG23 . VAL A 1 255 ? 121.572 108.070 117.592 1.00 42.03  ? 255 VAL A HG23 1 
ATOM 3656 N N    . ARG A 1 256 ? 124.973 108.491 116.767 1.00 45.28  ? 256 ARG A N    1 
ATOM 3657 C CA   . ARG A 1 256 ? 125.393 107.597 115.691 1.00 52.20  ? 256 ARG A CA   1 
ATOM 3658 C C    . ARG A 1 256 ? 125.377 106.175 116.250 1.00 57.15  ? 256 ARG A C    1 
ATOM 3659 O O    . ARG A 1 256 ? 126.401 105.656 116.697 1.00 60.23  ? 256 ARG A O    1 
ATOM 3660 C CB   . ARG A 1 256 ? 126.779 107.980 115.170 1.00 56.03  ? 256 ARG A CB   1 
ATOM 3661 C CG   . ARG A 1 256 ? 126.853 109.292 114.386 1.00 54.59  ? 256 ARG A CG   1 
ATOM 3662 C CD   . ARG A 1 256 ? 125.747 109.410 113.339 1.00 53.75  ? 256 ARG A CD   1 
ATOM 3663 N NE   . ARG A 1 256 ? 125.996 110.374 112.266 1.00 50.91  ? 256 ARG A NE   1 
ATOM 3664 C CZ   . ARG A 1 256 ? 126.557 111.574 112.388 1.00 52.49  ? 256 ARG A CZ   1 
ATOM 3665 N NH1  . ARG A 1 256 ? 126.834 112.105 113.567 1.00 55.14  ? 256 ARG A NH1  1 
ATOM 3666 N NH2  . ARG A 1 256 ? 126.827 112.274 111.289 1.00 54.18  ? 256 ARG A NH2  1 
ATOM 3667 H H    . ARG A 1 256 ? 125.534 108.524 117.418 1.00 46.19  ? 256 ARG A H    1 
ATOM 3668 H HA   . ARG A 1 256 ? 124.757 107.639 114.962 1.00 48.79  ? 256 ARG A HA   1 
ATOM 3669 H HB2  . ARG A 1 256 ? 127.379 108.059 115.929 1.00 55.16  ? 256 ARG A HB2  1 
ATOM 3670 H HB3  . ARG A 1 256 ? 127.089 107.274 114.583 1.00 56.50  ? 256 ARG A HB3  1 
ATOM 3671 H HG2  . ARG A 1 256 ? 126.759 110.008 115.030 1.00 52.54  ? 256 ARG A HG2  1 
ATOM 3672 H HG3  . ARG A 1 256 ? 127.705 109.354 113.928 1.00 53.91  ? 256 ARG A HG3  1 
ATOM 3673 H HD2  . ARG A 1 256 ? 125.617 108.540 112.931 1.00 54.67  ? 256 ARG A HD2  1 
ATOM 3674 H HD3  . ARG A 1 256 ? 124.931 109.686 113.786 1.00 51.96  ? 256 ARG A HD3  1 
ATOM 3675 H HE   . ARG A 1 256 ? 125.779 110.129 111.471 1.00 48.27  ? 256 ARG A HE   1 
ATOM 3676 H HH11 . ARG A 1 256 ? 126.667 111.688 114.290 1.00 55.46  ? 256 ARG A HH11 1 
ATOM 3677 H HH12 . ARG A 1 256 ? 127.187 112.888 113.605 1.00 55.28  ? 256 ARG A HH12 1 
ATOM 3678 H HH21 . ARG A 1 256 ? 126.649 111.941 110.517 1.00 50.00  ? 256 ARG A HH21 1 
ATOM 3679 H HH22 . ARG A 1 256 ? 127.181 113.056 111.349 1.00 51.71  ? 256 ARG A HH22 1 
ATOM 3680 N N    . ASP A 1 257 ? 124.206 105.547 116.218 1.00 51.15  ? 257 ASP A N    1 
ATOM 3681 C CA   . ASP A 1 257 ? 124.036 104.200 116.748 1.00 48.03  ? 257 ASP A CA   1 
ATOM 3682 C C    . ASP A 1 257 ? 122.686 103.677 116.279 1.00 52.17  ? 257 ASP A C    1 
ATOM 3683 O O    . ASP A 1 257 ? 121.826 104.440 115.832 1.00 57.85  ? 257 ASP A O    1 
ATOM 3684 C CB   . ASP A 1 257 ? 124.128 104.180 118.275 1.00 52.97  ? 257 ASP A CB   1 
ATOM 3685 C CG   . ASP A 1 257 ? 125.491 103.749 118.771 1.00 60.96  ? 257 ASP A CG   1 
ATOM 3686 O OD1  . ASP A 1 257 ? 125.862 102.576 118.554 1.00 58.61  ? 257 ASP A OD1  1 
ATOM 3687 O OD2  . ASP A 1 257 ? 126.192 104.584 119.381 1.00 62.52  ? 257 ASP A OD2  1 
ATOM 3688 H H    . ASP A 1 257 ? 123.487 105.887 115.892 1.00 51.16  ? 257 ASP A H    1 
ATOM 3689 H HA   . ASP A 1 257 ? 124.729 103.621 116.391 1.00 52.74  ? 257 ASP A HA   1 
ATOM 3690 H HB2  . ASP A 1 257 ? 123.951 105.070 118.616 1.00 54.42  ? 257 ASP A HB2  1 
ATOM 3691 H HB3  . ASP A 1 257 ? 123.473 103.554 118.623 1.00 53.47  ? 257 ASP A HB3  1 
ATOM 3692 N N    . TRP A 1 258 ? 122.508 102.360 116.392 1.00 56.64  ? 258 TRP A N    1 
ATOM 3693 C CA   . TRP A 1 258 ? 121.257 101.723 116.006 1.00 59.41  ? 258 TRP A CA   1 
ATOM 3694 C C    . TRP A 1 258 ? 120.352 101.414 117.190 1.00 59.70  ? 258 TRP A C    1 
ATOM 3695 O O    . TRP A 1 258 ? 119.142 101.258 116.995 1.00 60.92  ? 258 TRP A O    1 
ATOM 3696 C CB   . TRP A 1 258 ? 121.537 100.428 115.230 1.00 61.69  ? 258 TRP A CB   1 
ATOM 3697 C CG   . TRP A 1 258 ? 121.642 99.200  116.083 1.00 57.87  ? 258 TRP A CG   1 
ATOM 3698 C CD1  . TRP A 1 258 ? 122.781 98.663  116.609 1.00 61.99  ? 258 TRP A CD1  1 
ATOM 3699 C CD2  . TRP A 1 258 ? 120.568 98.348  116.499 1.00 51.72  ? 258 TRP A CD2  1 
ATOM 3700 N NE1  . TRP A 1 258 ? 122.482 97.533  117.330 1.00 66.05  ? 258 TRP A NE1  1 
ATOM 3701 C CE2  . TRP A 1 258 ? 121.130 97.319  117.279 1.00 57.92  ? 258 TRP A CE2  1 
ATOM 3702 C CE3  . TRP A 1 258 ? 119.186 98.358  116.292 1.00 56.91  ? 258 TRP A CE3  1 
ATOM 3703 C CZ2  . TRP A 1 258 ? 120.359 96.311  117.850 1.00 52.89  ? 258 TRP A CZ2  1 
ATOM 3704 C CZ3  . TRP A 1 258 ? 118.424 97.358  116.861 1.00 59.84  ? 258 TRP A CZ3  1 
ATOM 3705 C CH2  . TRP A 1 258 ? 119.011 96.348  117.630 1.00 55.41  ? 258 TRP A CH2  1 
ATOM 3706 H H    . TRP A 1 258 ? 123.102 101.814 116.690 1.00 56.69  ? 258 TRP A H    1 
ATOM 3707 H HA   . TRP A 1 258 ? 120.772 102.319 115.415 1.00 57.63  ? 258 TRP A HA   1 
ATOM 3708 H HB2  . TRP A 1 258 ? 120.817 100.285 114.596 1.00 58.70  ? 258 TRP A HB2  1 
ATOM 3709 H HB3  . TRP A 1 258 ? 122.376 100.528 114.753 1.00 58.98  ? 258 TRP A HB3  1 
ATOM 3710 H HD1  . TRP A 1 258 ? 123.636 99.011  116.496 1.00 60.25  ? 258 TRP A HD1  1 
ATOM 3711 H HE1  . TRP A 1 258 ? 123.051 97.041  117.747 1.00 62.70  ? 258 TRP A HE1  1 
ATOM 3712 H HE3  . TRP A 1 258 ? 118.788 99.027  115.783 1.00 57.90  ? 258 TRP A HE3  1 
ATOM 3713 H HZ2  . TRP A 1 258 ? 120.746 95.638  118.363 1.00 52.87  ? 258 TRP A HZ2  1 
ATOM 3714 H HZ3  . TRP A 1 258 ? 117.503 97.354  116.729 1.00 56.64  ? 258 TRP A HZ3  1 
ATOM 3715 H HH2  . TRP A 1 258 ? 118.472 95.686  118.000 1.00 52.09  ? 258 TRP A HH2  1 
ATOM 3716 N N    . ALA A 1 259 ? 120.902 101.317 118.400 1.00 60.27  ? 259 ALA A N    1 
ATOM 3717 C CA   . ALA A 1 259 ? 120.102 101.097 119.600 1.00 57.79  ? 259 ALA A CA   1 
ATOM 3718 C C    . ALA A 1 259 ? 119.748 102.410 120.289 1.00 57.48  ? 259 ALA A C    1 
ATOM 3719 O O    . ALA A 1 259 ? 118.586 102.641 120.642 1.00 60.74  ? 259 ALA A O    1 
ATOM 3720 C CB   . ALA A 1 259 ? 120.853 100.181 120.570 1.00 55.60  ? 259 ALA A CB   1 
ATOM 3721 H H    . ALA A 1 259 ? 121.746 101.374 118.552 1.00 58.76  ? 259 ALA A H    1 
ATOM 3722 H HA   . ALA A 1 259 ? 119.274 100.656 119.354 1.00 57.65  ? 259 ALA A HA   1 
ATOM 3723 H HB1  . ALA A 1 259 ? 121.691 100.603 120.817 1.00 57.65  ? 259 ALA A HB1  1 
ATOM 3724 H HB2  . ALA A 1 259 ? 120.308 100.044 121.360 1.00 54.49  ? 259 ALA A HB2  1 
ATOM 3725 H HB3  . ALA A 1 259 ? 121.026 99.332  120.135 1.00 56.12  ? 259 ALA A HB3  1 
ATOM 3726 N N    . LEU A 1 260 ? 120.741 103.281 120.481 1.00 53.30  ? 260 LEU A N    1 
ATOM 3727 C CA   . LEU A 1 260 ? 120.483 104.563 121.123 1.00 49.78  ? 260 LEU A CA   1 
ATOM 3728 C C    . LEU A 1 260 ? 119.483 105.384 120.322 1.00 50.52  ? 260 LEU A C    1 
ATOM 3729 O O    . LEU A 1 260 ? 118.607 106.038 120.895 1.00 53.36  ? 260 LEU A O    1 
ATOM 3730 C CB   . LEU A 1 260 ? 121.788 105.339 121.299 1.00 45.25  ? 260 LEU A CB   1 
ATOM 3731 C CG   . LEU A 1 260 ? 122.333 105.401 122.726 1.00 48.99  ? 260 LEU A CG   1 
ATOM 3732 C CD1  . LEU A 1 260 ? 123.776 105.882 122.730 1.00 49.31  ? 260 LEU A CD1  1 
ATOM 3733 C CD2  . LEU A 1 260 ? 121.466 106.301 123.590 1.00 48.23  ? 260 LEU A CD2  1 
ATOM 3734 H H    . LEU A 1 260 ? 121.560 103.151 120.251 1.00 53.25  ? 260 LEU A H    1 
ATOM 3735 H HA   . LEU A 1 260 ? 120.106 104.405 122.003 1.00 51.32  ? 260 LEU A HA   1 
ATOM 3736 H HB2  . LEU A 1 260 ? 122.470 104.927 120.746 1.00 49.83  ? 260 LEU A HB2  1 
ATOM 3737 H HB3  . LEU A 1 260 ? 121.643 106.252 121.006 1.00 45.59  ? 260 LEU A HB3  1 
ATOM 3738 H HG   . LEU A 1 260 ? 122.315 104.510 123.110 1.00 50.04  ? 260 LEU A HG   1 
ATOM 3739 H HD11 . LEU A 1 260 ? 123.812 106.773 122.347 1.00 50.04  ? 260 LEU A HD11 1 
ATOM 3740 H HD12 . LEU A 1 260 ? 124.099 105.902 123.645 1.00 48.11  ? 260 LEU A HD12 1 
ATOM 3741 H HD13 . LEU A 1 260 ? 124.314 105.272 122.202 1.00 50.13  ? 260 LEU A HD13 1 
ATOM 3742 H HD21 . LEU A 1 260 ? 121.419 107.180 123.182 1.00 48.73  ? 260 LEU A HD21 1 
ATOM 3743 H HD22 . LEU A 1 260 ? 120.577 105.918 123.653 1.00 47.98  ? 260 LEU A HD22 1 
ATOM 3744 H HD23 . LEU A 1 260 ? 121.861 106.366 124.473 1.00 49.51  ? 260 LEU A HD23 1 
ATOM 3745 N N    . LEU A 1 261 ? 119.606 105.371 118.994 1.00 49.53  ? 261 LEU A N    1 
ATOM 3746 C CA   . LEU A 1 261 ? 118.686 106.139 118.161 1.00 50.61  ? 261 LEU A CA   1 
ATOM 3747 C C    . LEU A 1 261 ? 117.253 105.652 118.340 1.00 53.96  ? 261 LEU A C    1 
ATOM 3748 O O    . LEU A 1 261 ? 116.331 106.453 118.533 1.00 53.77  ? 261 LEU A O    1 
ATOM 3749 C CB   . LEU A 1 261 ? 119.113 106.044 116.697 1.00 48.00  ? 261 LEU A CB   1 
ATOM 3750 C CG   . LEU A 1 261 ? 118.682 107.202 115.796 1.00 47.04  ? 261 LEU A CG   1 
ATOM 3751 C CD1  . LEU A 1 261 ? 119.706 107.434 114.700 1.00 49.01  ? 261 LEU A CD1  1 
ATOM 3752 C CD2  . LEU A 1 261 ? 117.317 106.935 115.197 1.00 51.72  ? 261 LEU A CD2  1 
ATOM 3753 H H    . LEU A 1 261 ? 120.203 104.931 118.559 1.00 50.97  ? 261 LEU A H    1 
ATOM 3754 H HA   . LEU A 1 261 ? 118.722 107.071 118.426 1.00 49.79  ? 261 LEU A HA   1 
ATOM 3755 H HB2  . LEU A 1 261 ? 120.081 106.000 116.665 1.00 49.94  ? 261 LEU A HB2  1 
ATOM 3756 H HB3  . LEU A 1 261 ? 118.740 105.231 116.322 1.00 50.94  ? 261 LEU A HB3  1 
ATOM 3757 H HG   . LEU A 1 261 ? 118.623 108.011 116.328 1.00 47.87  ? 261 LEU A HG   1 
ATOM 3758 H HD11 . LEU A 1 261 ? 119.809 106.618 114.186 1.00 49.99  ? 261 LEU A HD11 1 
ATOM 3759 H HD12 . LEU A 1 261 ? 119.394 108.150 114.124 1.00 50.13  ? 261 LEU A HD12 1 
ATOM 3760 H HD13 . LEU A 1 261 ? 120.552 107.680 115.105 1.00 48.08  ? 261 LEU A HD13 1 
ATOM 3761 H HD21 . LEU A 1 261 ? 117.076 107.679 114.625 1.00 54.10  ? 261 LEU A HD21 1 
ATOM 3762 H HD22 . LEU A 1 261 ? 117.355 106.116 114.678 1.00 52.77  ? 261 LEU A HD22 1 
ATOM 3763 H HD23 . LEU A 1 261 ? 116.669 106.845 115.913 1.00 51.62  ? 261 LEU A HD23 1 
ATOM 3764 N N    . GLN A 1 262 ? 117.047 104.336 118.289 1.00 53.67  ? 262 GLN A N    1 
ATOM 3765 C CA   . GLN A 1 262 ? 115.700 103.801 118.450 1.00 48.64  ? 262 GLN A CA   1 
ATOM 3766 C C    . GLN A 1 262 ? 115.152 104.128 119.834 1.00 46.28  ? 262 GLN A C    1 
ATOM 3767 O O    . GLN A 1 262 ? 113.990 104.531 119.971 1.00 52.84  ? 262 GLN A O    1 
ATOM 3768 C CB   . GLN A 1 262 ? 115.712 102.290 118.202 1.00 44.11  ? 262 GLN A CB   1 
ATOM 3769 C CG   . GLN A 1 262 ? 114.440 101.540 118.603 1.00 50.05  ? 262 GLN A CG   1 
ATOM 3770 C CD   . GLN A 1 262 ? 113.424 101.462 117.478 1.00 54.72  ? 262 GLN A CD   1 
ATOM 3771 O OE1  . GLN A 1 262 ? 112.253 101.793 117.661 1.00 58.98  ? 262 GLN A OE1  1 
ATOM 3772 N NE2  . GLN A 1 262 ? 113.864 101.006 116.311 1.00 56.07  ? 262 GLN A NE2  1 
ATOM 3773 H H    . GLN A 1 262 ? 117.658 103.743 118.165 1.00 52.95  ? 262 GLN A H    1 
ATOM 3774 H HA   . GLN A 1 262 ? 115.117 104.209 117.791 1.00 51.11  ? 262 GLN A HA   1 
ATOM 3775 H HB2  . GLN A 1 262 ? 115.864 102.140 117.257 1.00 49.46  ? 262 GLN A HB2  1 
ATOM 3776 H HB3  . GLN A 1 262 ? 116.445 101.904 118.708 1.00 48.11  ? 262 GLN A HB3  1 
ATOM 3777 H HG2  . GLN A 1 262 ? 114.683 100.631 118.840 1.00 50.01  ? 262 GLN A HG2  1 
ATOM 3778 H HG3  . GLN A 1 262 ? 114.011 101.966 119.359 1.00 50.00  ? 262 GLN A HG3  1 
ATOM 3779 H HE21 . GLN A 1 262 ? 114.689 100.780 116.220 1.00 54.17  ? 262 GLN A HE21 1 
ATOM 3780 H HE22 . GLN A 1 262 ? 113.326 100.942 115.644 1.00 57.54  ? 262 GLN A HE22 1 
ATOM 3781 N N    . LEU A 1 263 ? 115.976 103.967 120.872 1.00 39.97  ? 263 LEU A N    1 
ATOM 3782 C CA   . LEU A 1 263 ? 115.509 104.236 122.228 1.00 41.45  ? 263 LEU A CA   1 
ATOM 3783 C C    . LEU A 1 263 ? 115.131 105.703 122.401 1.00 45.08  ? 263 LEU A C    1 
ATOM 3784 O O    . LEU A 1 263 ? 114.086 106.019 122.985 1.00 49.32  ? 263 LEU A O    1 
ATOM 3785 C CB   . LEU A 1 263 ? 116.586 103.831 123.236 1.00 41.69  ? 263 LEU A CB   1 
ATOM 3786 C CG   . LEU A 1 263 ? 116.335 104.132 124.716 1.00 43.56  ? 263 LEU A CG   1 
ATOM 3787 C CD1  . LEU A 1 263 ? 115.464 103.055 125.337 1.00 47.49  ? 263 LEU A CD1  1 
ATOM 3788 C CD2  . LEU A 1 263 ? 117.650 104.250 125.464 1.00 43.12  ? 263 LEU A CD2  1 
ATOM 3789 H H    . LEU A 1 263 ? 116.794 103.708 120.817 1.00 46.20  ? 263 LEU A H    1 
ATOM 3790 H HA   . LEU A 1 263 ? 114.718 103.702 122.402 1.00 43.51  ? 263 LEU A HA   1 
ATOM 3791 H HB2  . LEU A 1 263 ? 116.717 102.872 123.162 1.00 43.82  ? 263 LEU A HB2  1 
ATOM 3792 H HB3  . LEU A 1 263 ? 117.410 104.281 122.992 1.00 44.98  ? 263 LEU A HB3  1 
ATOM 3793 H HG   . LEU A 1 263 ? 115.870 104.978 124.803 1.00 43.92  ? 263 LEU A HG   1 
ATOM 3794 H HD11 . LEU A 1 263 ? 114.622 103.014 124.857 1.00 45.38  ? 263 LEU A HD11 1 
ATOM 3795 H HD12 . LEU A 1 263 ? 115.922 102.203 125.274 1.00 45.03  ? 263 LEU A HD12 1 
ATOM 3796 H HD13 . LEU A 1 263 ? 115.303 103.277 126.268 1.00 47.59  ? 263 LEU A HD13 1 
ATOM 3797 H HD21 . LEU A 1 263 ? 118.140 103.417 125.375 1.00 43.79  ? 263 LEU A HD21 1 
ATOM 3798 H HD22 . LEU A 1 263 ? 118.166 104.980 125.087 1.00 45.07  ? 263 LEU A HD22 1 
ATOM 3799 H HD23 . LEU A 1 263 ? 117.465 104.425 126.401 1.00 43.27  ? 263 LEU A HD23 1 
ATOM 3800 N N    . VAL A 1 264 ? 115.966 106.616 121.900 1.00 46.18  ? 264 VAL A N    1 
ATOM 3801 C CA   . VAL A 1 264 ? 115.687 108.039 122.060 1.00 43.17  ? 264 VAL A CA   1 
ATOM 3802 C C    . VAL A 1 264 ? 114.452 108.431 121.261 1.00 44.98  ? 264 VAL A C    1 
ATOM 3803 O O    . VAL A 1 264 ? 113.670 109.289 121.684 1.00 48.70  ? 264 VAL A O    1 
ATOM 3804 C CB   . VAL A 1 264 ? 116.918 108.879 121.664 1.00 38.37  ? 264 VAL A CB   1 
ATOM 3805 C CG1  . VAL A 1 264 ? 116.944 109.155 120.168 1.00 41.04  ? 264 VAL A CG1  1 
ATOM 3806 C CG2  . VAL A 1 264 ? 116.945 110.183 122.444 1.00 48.94  ? 264 VAL A CG2  1 
ATOM 3807 H H    . VAL A 1 264 ? 116.690 106.439 121.471 1.00 46.99  ? 264 VAL A H    1 
ATOM 3808 H HA   . VAL A 1 264 ? 115.501 108.216 122.995 1.00 44.92  ? 264 VAL A HA   1 
ATOM 3809 H HB   . VAL A 1 264 ? 117.720 108.382 121.888 1.00 43.41  ? 264 VAL A HB   1 
ATOM 3810 H HG11 . VAL A 1 264 ? 117.790 109.571 119.941 1.00 45.04  ? 264 VAL A HG11 1 
ATOM 3811 H HG12 . VAL A 1 264 ? 116.853 108.317 119.695 1.00 41.39  ? 264 VAL A HG12 1 
ATOM 3812 H HG13 . VAL A 1 264 ? 116.216 109.752 119.933 1.00 43.68  ? 264 VAL A HG13 1 
ATOM 3813 H HG21 . VAL A 1 264 ? 117.719 110.699 122.169 1.00 48.71  ? 264 VAL A HG21 1 
ATOM 3814 H HG22 . VAL A 1 264 ? 116.133 110.678 122.255 1.00 46.91  ? 264 VAL A HG22 1 
ATOM 3815 H HG23 . VAL A 1 264 ? 116.999 109.983 123.391 1.00 47.82  ? 264 VAL A HG23 1 
ATOM 3816 N N    . VAL A 1 265 ? 114.257 107.817 120.092 1.00 43.40  ? 265 VAL A N    1 
ATOM 3817 C CA   . VAL A 1 265 ? 113.075 108.126 119.296 1.00 44.18  ? 265 VAL A CA   1 
ATOM 3818 C C    . VAL A 1 265 ? 111.812 107.631 119.991 1.00 48.43  ? 265 VAL A C    1 
ATOM 3819 O O    . VAL A 1 265 ? 110.777 108.306 119.972 1.00 53.85  ? 265 VAL A O    1 
ATOM 3820 C CB   . VAL A 1 265 ? 113.217 107.532 117.883 1.00 48.71  ? 265 VAL A CB   1 
ATOM 3821 C CG1  . VAL A 1 265 ? 111.904 107.629 117.124 1.00 54.24  ? 265 VAL A CG1  1 
ATOM 3822 C CG2  . VAL A 1 265 ? 114.313 108.251 117.118 1.00 56.32  ? 265 VAL A CG2  1 
ATOM 3823 H H    . VAL A 1 265 ? 114.782 107.231 119.747 1.00 46.26  ? 265 VAL A H    1 
ATOM 3824 H HA   . VAL A 1 265 ? 113.004 109.090 119.206 1.00 47.91  ? 265 VAL A HA   1 
ATOM 3825 H HB   . VAL A 1 265 ? 113.459 106.595 117.952 1.00 50.04  ? 265 VAL A HB   1 
ATOM 3826 H HG11 . VAL A 1 265 ? 112.033 107.273 116.231 1.00 55.17  ? 265 VAL A HG11 1 
ATOM 3827 H HG12 . VAL A 1 265 ? 111.224 107.115 117.581 1.00 55.30  ? 265 VAL A HG12 1 
ATOM 3828 H HG13 . VAL A 1 265 ? 111.637 108.560 117.074 1.00 55.54  ? 265 VAL A HG13 1 
ATOM 3829 H HG21 . VAL A 1 265 ? 114.497 107.765 116.299 1.00 55.10  ? 265 VAL A HG21 1 
ATOM 3830 H HG22 . VAL A 1 265 ? 114.013 109.149 116.908 1.00 54.32  ? 265 VAL A HG22 1 
ATOM 3831 H HG23 . VAL A 1 265 ? 115.111 108.292 117.665 1.00 51.77  ? 265 VAL A HG23 1 
ATOM 3832 N N    . SER A 1 266 ? 111.866 106.448 120.604 1.00 47.77  ? 266 SER A N    1 
ATOM 3833 C CA   . SER A 1 266 ? 110.654 105.815 121.109 1.00 46.46  ? 266 SER A CA   1 
ATOM 3834 C C    . SER A 1 266 ? 110.373 106.086 122.584 1.00 47.74  ? 266 SER A C    1 
ATOM 3835 O O    . SER A 1 266 ? 109.316 105.674 123.073 1.00 52.95  ? 266 SER A O    1 
ATOM 3836 C CB   . SER A 1 266 ? 110.726 104.301 120.890 1.00 45.95  ? 266 SER A CB   1 
ATOM 3837 O OG   . SER A 1 266 ? 111.272 103.649 122.022 1.00 46.22  ? 266 SER A OG   1 
ATOM 3838 H H    . SER A 1 266 ? 112.585 105.996 120.738 1.00 48.48  ? 266 SER A H    1 
ATOM 3839 H HA   . SER A 1 266 ? 109.897 106.146 120.602 1.00 47.39  ? 266 SER A HA   1 
ATOM 3840 H HB2  . SER A 1 266 ? 109.830 103.965 120.734 1.00 46.24  ? 266 SER A HB2  1 
ATOM 3841 H HB3  . SER A 1 266 ? 111.287 104.120 120.120 1.00 47.54  ? 266 SER A HB3  1 
ATOM 3842 H HG   . SER A 1 266 ? 112.053 103.923 122.163 1.00 46.20  ? 266 SER A HG   1 
ATOM 3843 N N    . VAL A 1 267 ? 111.267 106.754 123.306 1.00 44.06  ? 267 VAL A N    1 
ATOM 3844 C CA   . VAL A 1 267 ? 111.042 106.984 124.734 1.00 41.05  ? 267 VAL A CA   1 
ATOM 3845 C C    . VAL A 1 267 ? 109.973 108.045 125.003 1.00 49.49  ? 267 VAL A C    1 
ATOM 3846 O O    . VAL A 1 267 ? 109.245 107.916 125.998 1.00 56.57  ? 267 VAL A O    1 
ATOM 3847 C CB   . VAL A 1 267 ? 112.362 107.336 125.448 1.00 42.91  ? 267 VAL A CB   1 
ATOM 3848 C CG1  . VAL A 1 267 ? 112.862 108.731 125.082 1.00 52.54  ? 267 VAL A CG1  1 
ATOM 3849 C CG2  . VAL A 1 267 ? 112.192 107.210 126.955 1.00 43.40  ? 267 VAL A CG2  1 
ATOM 3850 H H    . VAL A 1 267 ? 112.001 107.081 123.001 1.00 46.09  ? 267 VAL A H    1 
ATOM 3851 H HA   . VAL A 1 267 ? 110.722 106.155 125.123 1.00 42.67  ? 267 VAL A HA   1 
ATOM 3852 H HB   . VAL A 1 267 ? 113.041 106.699 125.175 1.00 44.44  ? 267 VAL A HB   1 
ATOM 3853 H HG11 . VAL A 1 267 ? 112.147 109.378 125.164 1.00 49.53  ? 267 VAL A HG11 1 
ATOM 3854 H HG12 . VAL A 1 267 ? 113.580 108.967 125.690 1.00 50.91  ? 267 VAL A HG12 1 
ATOM 3855 H HG13 . VAL A 1 267 ? 113.202 108.715 124.174 1.00 49.60  ? 267 VAL A HG13 1 
ATOM 3856 H HG21 . VAL A 1 267 ? 113.045 107.380 127.383 1.00 45.42  ? 267 VAL A HG21 1 
ATOM 3857 H HG22 . VAL A 1 267 ? 111.535 107.857 127.255 1.00 43.52  ? 267 VAL A HG22 1 
ATOM 3858 H HG23 . VAL A 1 267 ? 111.891 106.311 127.164 1.00 45.67  ? 267 VAL A HG23 1 
ATOM 3859 N N    . PRO A 1 268 ? 109.825 109.099 124.191 1.00 47.33  ? 268 PRO A N    1 
ATOM 3860 C CA   . PRO A 1 268 ? 108.831 110.136 124.534 1.00 46.08  ? 268 PRO A CA   1 
ATOM 3861 C C    . PRO A 1 268 ? 107.394 109.637 124.537 1.00 48.54  ? 268 PRO A C    1 
ATOM 3862 O O    . PRO A 1 268 ? 106.513 110.301 125.107 1.00 46.78  ? 268 PRO A O    1 
ATOM 3863 C CB   . PRO A 1 268 ? 109.045 111.207 123.453 1.00 48.27  ? 268 PRO A CB   1 
ATOM 3864 C CG   . PRO A 1 268 ? 110.365 110.904 122.850 1.00 47.40  ? 268 PRO A CG   1 
ATOM 3865 C CD   . PRO A 1 268 ? 110.511 109.428 122.930 1.00 47.60  ? 268 PRO A CD   1 
ATOM 3866 H HA   . PRO A 1 268 ? 109.037 110.519 125.401 1.00 46.55  ? 268 PRO A HA   1 
ATOM 3867 H HB2  . PRO A 1 268 ? 108.342 111.144 122.788 1.00 50.63  ? 268 PRO A HB2  1 
ATOM 3868 H HB3  . PRO A 1 268 ? 109.050 112.085 123.864 1.00 50.31  ? 268 PRO A HB3  1 
ATOM 3869 H HG2  . PRO A 1 268 ? 110.378 111.200 121.927 1.00 51.73  ? 268 PRO A HG2  1 
ATOM 3870 H HG3  . PRO A 1 268 ? 111.064 111.344 123.360 1.00 48.70  ? 268 PRO A HG3  1 
ATOM 3871 H HD2  . PRO A 1 268 ? 110.064 109.001 122.183 1.00 49.73  ? 268 PRO A HD2  1 
ATOM 3872 H HD3  . PRO A 1 268 ? 111.449 109.193 122.963 1.00 47.86  ? 268 PRO A HD3  1 
ATOM 3873 N N    . PHE A 1 269 ? 107.116 108.496 123.909 1.00 47.56  ? 269 PHE A N    1 
ATOM 3874 C CA   . PHE A 1 269 ? 105.748 108.006 123.891 1.00 43.99  ? 269 PHE A CA   1 
ATOM 3875 C C    . PHE A 1 269 ? 105.270 107.597 125.278 1.00 40.82  ? 269 PHE A C    1 
ATOM 3876 O O    . PHE A 1 269 ? 104.060 107.515 125.501 1.00 47.77  ? 269 PHE A O    1 
ATOM 3877 C CB   . PHE A 1 269 ? 105.623 106.852 122.900 1.00 45.58  ? 269 PHE A CB   1 
ATOM 3878 C CG   . PHE A 1 269 ? 105.567 107.303 121.468 1.00 51.58  ? 269 PHE A CG   1 
ATOM 3879 C CD1  . PHE A 1 269 ? 104.392 107.800 120.931 1.00 54.38  ? 269 PHE A CD1  1 
ATOM 3880 C CD2  . PHE A 1 269 ? 106.694 107.255 120.667 1.00 56.23  ? 269 PHE A CD2  1 
ATOM 3881 C CE1  . PHE A 1 269 ? 104.339 108.227 119.618 1.00 52.84  ? 269 PHE A CE1  1 
ATOM 3882 C CE2  . PHE A 1 269 ? 106.646 107.681 119.353 1.00 54.28  ? 269 PHE A CE2  1 
ATOM 3883 C CZ   . PHE A 1 269 ? 105.468 108.167 118.830 1.00 51.57  ? 269 PHE A CZ   1 
ATOM 3884 H H    . PHE A 1 269 ? 107.687 108.002 123.498 1.00 48.28  ? 269 PHE A H    1 
ATOM 3885 H HA   . PHE A 1 269 ? 105.177 108.721 123.577 1.00 46.67  ? 269 PHE A HA   1 
ATOM 3886 H HB2  . PHE A 1 269 ? 106.390 106.267 122.999 1.00 46.42  ? 269 PHE A HB2  1 
ATOM 3887 H HB3  . PHE A 1 269 ? 104.807 106.361 123.089 1.00 45.68  ? 269 PHE A HB3  1 
ATOM 3888 H HD1  . PHE A 1 269 ? 103.627 107.843 121.458 1.00 51.62  ? 269 PHE A HD1  1 
ATOM 3889 H HD2  . PHE A 1 269 ? 107.491 106.928 121.015 1.00 51.64  ? 269 PHE A HD2  1 
ATOM 3890 H HE1  . PHE A 1 269 ? 103.543 108.555 119.267 1.00 52.52  ? 269 PHE A HE1  1 
ATOM 3891 H HE2  . PHE A 1 269 ? 107.409 107.640 118.823 1.00 54.64  ? 269 PHE A HE2  1 
ATOM 3892 H HZ   . PHE A 1 269 ? 105.434 108.454 117.946 1.00 53.50  ? 269 PHE A HZ   1 
ATOM 3893 N N    . PHE A 1 270 ? 106.184 107.379 126.227 1.00 38.79  ? 270 PHE A N    1 
ATOM 3894 C CA   . PHE A 1 270 ? 105.767 107.189 127.613 1.00 39.27  ? 270 PHE A CA   1 
ATOM 3895 C C    . PHE A 1 270 ? 105.088 108.443 128.153 1.00 42.81  ? 270 PHE A C    1 
ATOM 3896 O O    . PHE A 1 270 ? 104.005 108.370 128.745 1.00 47.26  ? 270 PHE A O    1 
ATOM 3897 C CB   . PHE A 1 270 ? 106.972 106.812 128.478 1.00 37.33  ? 270 PHE A CB   1 
ATOM 3898 C CG   . PHE A 1 270 ? 107.458 105.403 128.268 1.00 41.84  ? 270 PHE A CG   1 
ATOM 3899 C CD1  . PHE A 1 270 ? 106.563 104.347 128.201 1.00 49.30  ? 270 PHE A CD1  1 
ATOM 3900 C CD2  . PHE A 1 270 ? 108.809 105.135 128.139 1.00 44.23  ? 270 PHE A CD2  1 
ATOM 3901 C CE1  . PHE A 1 270 ? 107.006 103.055 128.011 1.00 50.88  ? 270 PHE A CE1  1 
ATOM 3902 C CE2  . PHE A 1 270 ? 109.258 103.843 127.947 1.00 50.69  ? 270 PHE A CE2  1 
ATOM 3903 C CZ   . PHE A 1 270 ? 108.355 102.803 127.883 1.00 50.04  ? 270 PHE A CZ   1 
ATOM 3904 H H    . PHE A 1 270 ? 107.032 107.337 126.096 1.00 43.68  ? 270 PHE A H    1 
ATOM 3905 H HA   . PHE A 1 270 ? 105.119 106.471 127.652 1.00 42.62  ? 270 PHE A HA   1 
ATOM 3906 H HB2  . PHE A 1 270 ? 107.706 107.412 128.270 1.00 42.72  ? 270 PHE A HB2  1 
ATOM 3907 H HB3  . PHE A 1 270 ? 106.727 106.905 129.412 1.00 38.98  ? 270 PHE A HB3  1 
ATOM 3908 H HD1  . PHE A 1 270 ? 105.651 104.511 128.287 1.00 45.95  ? 270 PHE A HD1  1 
ATOM 3909 H HD2  . PHE A 1 270 ? 109.422 105.833 128.181 1.00 44.49  ? 270 PHE A HD2  1 
ATOM 3910 H HE1  . PHE A 1 270 ? 106.395 102.355 127.967 1.00 46.27  ? 270 PHE A HE1  1 
ATOM 3911 H HE2  . PHE A 1 270 ? 110.168 103.675 127.861 1.00 48.61  ? 270 PHE A HE2  1 
ATOM 3912 H HZ   . PHE A 1 270 ? 108.656 101.933 127.754 1.00 46.36  ? 270 PHE A HZ   1 
ATOM 3913 N N    . LEU A 1 271 ? 105.704 109.609 127.946 1.00 49.12  ? 271 LEU A N    1 
ATOM 3914 C CA   . LEU A 1 271 ? 105.052 110.858 128.331 1.00 49.78  ? 271 LEU A CA   1 
ATOM 3915 C C    . LEU A 1 271 ? 103.768 111.064 127.541 1.00 48.68  ? 271 LEU A C    1 
ATOM 3916 O O    . LEU A 1 271 ? 102.761 111.542 128.082 1.00 48.18  ? 271 LEU A O    1 
ATOM 3917 C CB   . LEU A 1 271 ? 106.000 112.038 128.120 1.00 46.33  ? 271 LEU A CB   1 
ATOM 3918 C CG   . LEU A 1 271 ? 107.316 112.007 128.897 1.00 53.30  ? 271 LEU A CG   1 
ATOM 3919 C CD1  . LEU A 1 271 ? 108.425 112.664 128.091 1.00 54.09  ? 271 LEU A CD1  1 
ATOM 3920 C CD2  . LEU A 1 271 ? 107.155 112.691 130.246 1.00 48.62  ? 271 LEU A CD2  1 
ATOM 3921 H H    . LEU A 1 271 ? 106.482 109.703 127.593 1.00 47.65  ? 271 LEU A H    1 
ATOM 3922 H HA   . LEU A 1 271 ? 104.823 110.819 129.273 1.00 47.97  ? 271 LEU A HA   1 
ATOM 3923 H HB2  . LEU A 1 271 ? 106.223 112.081 127.177 1.00 47.10  ? 271 LEU A HB2  1 
ATOM 3924 H HB3  . LEU A 1 271 ? 105.534 112.849 128.376 1.00 45.86  ? 271 LEU A HB3  1 
ATOM 3925 H HG   . LEU A 1 271 ? 107.568 111.084 129.058 1.00 53.52  ? 271 LEU A HG   1 
ATOM 3926 H HD11 . LEU A 1 271 ? 109.245 112.646 128.608 1.00 52.59  ? 271 LEU A HD11 1 
ATOM 3927 H HD12 . LEU A 1 271 ? 108.545 112.174 127.262 1.00 51.75  ? 271 LEU A HD12 1 
ATOM 3928 H HD13 . LEU A 1 271 ? 108.173 113.581 127.899 1.00 52.94  ? 271 LEU A HD13 1 
ATOM 3929 H HD21 . LEU A 1 271 ? 108.004 112.672 130.713 1.00 50.71  ? 271 LEU A HD21 1 
ATOM 3930 H HD22 . LEU A 1 271 ? 106.877 113.609 130.102 1.00 48.13  ? 271 LEU A HD22 1 
ATOM 3931 H HD23 . LEU A 1 271 ? 106.483 112.219 130.761 1.00 47.17  ? 271 LEU A HD23 1 
ATOM 3932 N N    . CYS A 1 272 ? 103.789 110.716 126.253 1.00 46.64  ? 272 CYS A N    1 
ATOM 3933 C CA   . CYS A 1 272 ? 102.584 110.850 125.438 1.00 51.68  ? 272 CYS A CA   1 
ATOM 3934 C C    . CYS A 1 272 ? 101.428 110.065 126.047 1.00 48.67  ? 272 CYS A C    1 
ATOM 3935 O O    . CYS A 1 272 ? 100.300 110.562 126.136 1.00 47.20  ? 272 CYS A O    1 
ATOM 3936 C CB   . CYS A 1 272 ? 102.855 110.382 124.010 1.00 55.74  ? 272 CYS A CB   1 
ATOM 3937 S SG   . CYS A 1 272 ? 103.849 111.530 123.028 1.00 80.59  ? 272 CYS A SG   1 
ATOM 3938 H H    . CYS A 1 272 ? 104.474 110.405 125.835 1.00 47.37  ? 272 CYS A H    1 
ATOM 3939 H HA   . CYS A 1 272 ? 102.329 111.780 125.402 1.00 51.49  ? 272 CYS A HA   1 
ATOM 3940 H HB2  . CYS A 1 272 ? 103.315 109.532 124.046 1.00 52.05  ? 272 CYS A HB2  1 
ATOM 3941 H HB3  . CYS A 1 272 ? 102.005 110.271 123.556 1.00 53.35  ? 272 CYS A HB3  1 
ATOM 3942 H HG   . CYS A 1 272 ? 103.998 111.076 121.928 1.00 59.44  ? 272 CYS A HG   1 
ATOM 3943 N N    . PHE A 1 273 ? 101.693 108.828 126.468 1.00 48.44  ? 273 PHE A N    1 
ATOM 3944 C CA   . PHE A 1 273 ? 100.678 108.044 127.162 1.00 43.88  ? 273 PHE A CA   1 
ATOM 3945 C C    . PHE A 1 273 ? 100.284 108.696 128.480 1.00 50.96  ? 273 PHE A C    1 
ATOM 3946 O O    . PHE A 1 273 ? 99.098  108.757 128.823 1.00 52.42  ? 273 PHE A O    1 
ATOM 3947 C CB   . PHE A 1 273 ? 101.196 106.624 127.402 1.00 36.30  ? 273 PHE A CB   1 
ATOM 3948 C CG   . PHE A 1 273 ? 100.546 105.926 128.566 1.00 40.19  ? 273 PHE A CG   1 
ATOM 3949 C CD1  . PHE A 1 273 ? 101.060 106.053 129.847 1.00 48.01  ? 273 PHE A CD1  1 
ATOM 3950 C CD2  . PHE A 1 273 ? 99.426  105.139 128.378 1.00 41.89  ? 273 PHE A CD2  1 
ATOM 3951 C CE1  . PHE A 1 273 ? 100.463 105.414 130.915 1.00 55.76  ? 273 PHE A CE1  1 
ATOM 3952 C CE2  . PHE A 1 273 ? 98.826  104.498 129.443 1.00 46.53  ? 273 PHE A CE2  1 
ATOM 3953 C CZ   . PHE A 1 273 ? 99.345  104.636 130.712 1.00 53.50  ? 273 PHE A CZ   1 
ATOM 3954 H H    . PHE A 1 273 ? 102.446 108.426 126.366 1.00 47.82  ? 273 PHE A H    1 
ATOM 3955 H HA   . PHE A 1 273 ? 99.886  107.986 126.606 1.00 44.66  ? 273 PHE A HA   1 
ATOM 3956 H HB2  . PHE A 1 273 ? 101.029 106.093 126.608 1.00 40.12  ? 273 PHE A HB2  1 
ATOM 3957 H HB3  . PHE A 1 273 ? 102.149 106.664 127.577 1.00 42.77  ? 273 PHE A HB3  1 
ATOM 3958 H HD1  . PHE A 1 273 ? 101.813 106.579 129.990 1.00 47.82  ? 273 PHE A HD1  1 
ATOM 3959 H HD2  . PHE A 1 273 ? 99.070  105.044 127.525 1.00 42.29  ? 273 PHE A HD2  1 
ATOM 3960 H HE1  . PHE A 1 273 ? 100.816 105.508 131.770 1.00 53.79  ? 273 PHE A HE1  1 
ATOM 3961 H HE2  . PHE A 1 273 ? 98.072  103.973 129.304 1.00 45.91  ? 273 PHE A HE2  1 
ATOM 3962 H HZ   . PHE A 1 273 ? 98.942  104.203 131.430 1.00 51.74  ? 273 PHE A HZ   1 
ATOM 3963 N N    . VAL A 1 274 ? 101.268 109.187 129.235 1.00 51.63  ? 274 VAL A N    1 
ATOM 3964 C CA   . VAL A 1 274 ? 100.999 109.665 130.589 1.00 44.42  ? 274 VAL A CA   1 
ATOM 3965 C C    . VAL A 1 274 ? 100.044 110.851 130.557 1.00 47.12  ? 274 VAL A C    1 
ATOM 3966 O O    . VAL A 1 274 ? 99.088  110.920 131.338 1.00 45.55  ? 274 VAL A O    1 
ATOM 3967 C CB   . VAL A 1 274 ? 102.316 110.016 131.304 1.00 45.04  ? 274 VAL A CB   1 
ATOM 3968 C CG1  . VAL A 1 274 ? 102.093 111.101 132.352 1.00 49.01  ? 274 VAL A CG1  1 
ATOM 3969 C CG2  . VAL A 1 274 ? 102.917 108.772 131.938 1.00 49.73  ? 274 VAL A CG2  1 
ATOM 3970 H H    . VAL A 1 274 ? 102.089 109.253 128.990 1.00 49.05  ? 274 VAL A H    1 
ATOM 3971 H HA   . VAL A 1 274 ? 100.570 108.955 131.091 1.00 45.62  ? 274 VAL A HA   1 
ATOM 3972 H HB   . VAL A 1 274 ? 102.949 110.355 130.652 1.00 46.49  ? 274 VAL A HB   1 
ATOM 3973 H HG11 . VAL A 1 274 ? 102.874 111.143 132.925 1.00 49.64  ? 274 VAL A HG11 1 
ATOM 3974 H HG12 . VAL A 1 274 ? 101.967 111.956 131.911 1.00 48.74  ? 274 VAL A HG12 1 
ATOM 3975 H HG13 . VAL A 1 274 ? 101.313 110.877 132.883 1.00 47.62  ? 274 VAL A HG13 1 
ATOM 3976 H HG21 . VAL A 1 274 ? 103.746 109.012 132.382 1.00 48.64  ? 274 VAL A HG21 1 
ATOM 3977 H HG22 . VAL A 1 274 ? 102.289 108.411 132.584 1.00 50.16  ? 274 VAL A HG22 1 
ATOM 3978 H HG23 . VAL A 1 274 ? 103.091 108.116 131.244 1.00 47.72  ? 274 VAL A HG23 1 
ATOM 3979 N N    . TYR A 1 275 ? 100.289 111.809 129.663 1.00 53.08  ? 275 TYR A N    1 
ATOM 3980 C CA   . TYR A 1 275 ? 99.440  112.995 129.623 1.00 57.66  ? 275 TYR A CA   1 
ATOM 3981 C C    . TYR A 1 275 ? 98.193  112.805 128.768 1.00 58.76  ? 275 TYR A C    1 
ATOM 3982 O O    . TYR A 1 275 ? 97.348  113.705 128.732 1.00 62.15  ? 275 TYR A O    1 
ATOM 3983 C CB   . TYR A 1 275 ? 100.241 114.211 129.132 1.00 51.56  ? 275 TYR A CB   1 
ATOM 3984 C CG   . TYR A 1 275 ? 100.335 114.384 127.628 1.00 49.38  ? 275 TYR A CG   1 
ATOM 3985 C CD1  . TYR A 1 275 ? 99.266  114.882 126.893 1.00 49.65  ? 275 TYR A CD1  1 
ATOM 3986 C CD2  . TYR A 1 275 ? 101.505 114.082 126.949 1.00 51.84  ? 275 TYR A CD2  1 
ATOM 3987 C CE1  . TYR A 1 275 ? 99.352  115.047 125.527 1.00 55.24  ? 275 TYR A CE1  1 
ATOM 3988 C CE2  . TYR A 1 275 ? 101.600 114.252 125.581 1.00 49.50  ? 275 TYR A CE2  1 
ATOM 3989 C CZ   . TYR A 1 275 ? 100.522 114.732 124.876 1.00 56.43  ? 275 TYR A CZ   1 
ATOM 3990 O OH   . TYR A 1 275 ? 100.615 114.899 123.514 1.00 64.93  ? 275 TYR A OH   1 
ATOM 3991 H H    . TYR A 1 275 ? 100.924 111.796 129.083 1.00 50.88  ? 275 TYR A H    1 
ATOM 3992 H HA   . TYR A 1 275 ? 99.144  113.191 130.525 1.00 54.37  ? 275 TYR A HA   1 
ATOM 3993 H HB2  . TYR A 1 275 ? 99.828  115.012 129.489 1.00 51.21  ? 275 TYR A HB2  1 
ATOM 3994 H HB3  . TYR A 1 275 ? 101.147 114.137 129.471 1.00 51.69  ? 275 TYR A HB3  1 
ATOM 3995 H HD1  . TYR A 1 275 ? 98.472  115.094 127.328 1.00 52.35  ? 275 TYR A HD1  1 
ATOM 3996 H HD2  . TYR A 1 275 ? 102.236 113.755 127.421 1.00 52.07  ? 275 TYR A HD2  1 
ATOM 3997 H HE1  . TYR A 1 275 ? 98.625  115.374 125.052 1.00 54.95  ? 275 TYR A HE1  1 
ATOM 3998 H HE2  . TYR A 1 275 ? 102.389 114.037 125.138 1.00 51.19  ? 275 TYR A HE2  1 
ATOM 3999 H HH   . TYR A 1 275 ? 99.878  115.158 123.205 1.00 58.28  ? 275 TYR A HH   1 
ATOM 4000 N N    . SER A 1 276 ? 98.047  111.664 128.095 1.00 53.04  ? 276 SER A N    1 
ATOM 4001 C CA   . SER A 1 276 ? 96.906  111.413 127.224 1.00 51.31  ? 276 SER A CA   1 
ATOM 4002 C C    . SER A 1 276 ? 95.680  110.906 127.975 1.00 52.83  ? 276 SER A C    1 
ATOM 4003 O O    . SER A 1 276 ? 94.777  110.344 127.346 1.00 51.44  ? 276 SER A O    1 
ATOM 4004 C CB   . SER A 1 276 ? 97.290  110.412 126.134 1.00 48.43  ? 276 SER A CB   1 
ATOM 4005 O OG   . SER A 1 276 ? 96.139  109.909 125.478 1.00 49.87  ? 276 SER A OG   1 
ATOM 4006 H H    . SER A 1 276 ? 98.605  111.011 128.127 1.00 51.36  ? 276 SER A H    1 
ATOM 4007 H HA   . SER A 1 276 ? 96.660  112.244 126.788 1.00 52.71  ? 276 SER A HA   1 
ATOM 4008 H HB2  . SER A 1 276 ? 97.855  110.857 125.482 1.00 50.48  ? 276 SER A HB2  1 
ATOM 4009 H HB3  . SER A 1 276 ? 97.771  109.673 126.539 1.00 48.28  ? 276 SER A HB3  1 
ATOM 4010 H HG   . SER A 1 276 ? 95.706  110.540 125.134 1.00 49.14  ? 276 SER A HG   1 
ATOM 4011 N N    . CYS A 1 277 ? 95.624  111.085 129.295 1.00 57.11  ? 277 CYS A N    1 
ATOM 4012 C CA   . CYS A 1 277 ? 94.475  110.651 130.078 1.00 61.06  ? 277 CYS A CA   1 
ATOM 4013 C C    . CYS A 1 277 ? 93.473  111.765 130.346 1.00 60.25  ? 277 CYS A C    1 
ATOM 4014 O O    . CYS A 1 277 ? 92.316  111.470 130.665 1.00 63.77  ? 277 CYS A O    1 
ATOM 4015 C CB   . CYS A 1 277 ? 94.939  110.065 131.418 1.00 60.62  ? 277 CYS A CB   1 
ATOM 4016 S SG   . CYS A 1 277 ? 95.528  108.359 131.315 1.00 79.16  ? 277 CYS A SG   1 
ATOM 4017 H H    . CYS A 1 277 ? 96.243  111.456 129.762 1.00 55.99  ? 277 CYS A H    1 
ATOM 4018 H HA   . CYS A 1 277 ? 94.013  109.948 129.595 1.00 60.50  ? 277 CYS A HA   1 
ATOM 4019 H HB2  . CYS A 1 277 ? 95.667  110.608 131.759 1.00 60.43  ? 277 CYS A HB2  1 
ATOM 4020 H HB3  . CYS A 1 277 ? 94.196  110.085 132.040 1.00 61.12  ? 277 CYS A HB3  1 
ATOM 4021 H HG   . CYS A 1 277 ? 95.863  107.995 132.408 1.00 70.40  ? 277 CYS A HG   1 
ATOM 4022 N N    . TRP A 1 278 ? 93.880  113.028 130.223 1.00 55.30  ? 278 TRP A N    1 
ATOM 4023 C CA   . TRP A 1 278 ? 92.978  114.154 130.427 1.00 59.52  ? 278 TRP A CA   1 
ATOM 4024 C C    . TRP A 1 278 ? 92.300  114.620 129.147 1.00 54.65  ? 278 TRP A C    1 
ATOM 4025 O O    . TRP A 1 278 ? 91.430  115.495 129.210 1.00 48.78  ? 278 TRP A O    1 
ATOM 4026 C CB   . TRP A 1 278 ? 93.735  115.326 131.059 1.00 59.23  ? 278 TRP A CB   1 
ATOM 4027 C CG   . TRP A 1 278 ? 93.960  115.147 132.525 1.00 55.89  ? 278 TRP A CG   1 
ATOM 4028 C CD1  . TRP A 1 278 ? 93.117  115.513 133.533 1.00 60.29  ? 278 TRP A CD1  1 
ATOM 4029 C CD2  . TRP A 1 278 ? 95.095  114.541 133.151 1.00 59.86  ? 278 TRP A CD2  1 
ATOM 4030 N NE1  . TRP A 1 278 ? 93.660  115.179 134.749 1.00 61.52  ? 278 TRP A NE1  1 
ATOM 4031 C CE2  . TRP A 1 278 ? 94.875  114.580 134.541 1.00 63.32  ? 278 TRP A CE2  1 
ATOM 4032 C CE3  . TRP A 1 278 ? 96.278  113.971 132.670 1.00 57.49  ? 278 TRP A CE3  1 
ATOM 4033 C CZ2  . TRP A 1 278 ? 95.794  114.073 135.457 1.00 63.41  ? 278 TRP A CZ2  1 
ATOM 4034 C CZ3  . TRP A 1 278 ? 97.188  113.469 133.580 1.00 51.89  ? 278 TRP A CZ3  1 
ATOM 4035 C CH2  . TRP A 1 278 ? 96.941  113.522 134.958 1.00 56.36  ? 278 TRP A CH2  1 
ATOM 4036 H H    . TRP A 1 278 ? 94.683  113.259 130.021 1.00 55.97  ? 278 TRP A H    1 
ATOM 4037 H HA   . TRP A 1 278 ? 92.282  113.887 131.048 1.00 58.74  ? 278 TRP A HA   1 
ATOM 4038 H HB2  . TRP A 1 278 ? 94.602  115.410 130.631 1.00 59.40  ? 278 TRP A HB2  1 
ATOM 4039 H HB3  . TRP A 1 278 ? 93.221  116.139 130.932 1.00 58.56  ? 278 TRP A HB3  1 
ATOM 4040 H HD1  . TRP A 1 278 ? 92.294  115.931 133.414 1.00 60.88  ? 278 TRP A HD1  1 
ATOM 4041 H HE1  . TRP A 1 278 ? 93.297  115.322 135.515 1.00 60.58  ? 278 TRP A HE1  1 
ATOM 4042 H HE3  . TRP A 1 278 ? 96.448  113.933 131.757 1.00 57.19  ? 278 TRP A HE3  1 
ATOM 4043 H HZ2  . TRP A 1 278 ? 95.632  114.108 136.372 1.00 61.63  ? 278 TRP A HZ2  1 
ATOM 4044 H HZ3  . TRP A 1 278 ? 97.979  113.088 133.272 1.00 53.18  ? 278 TRP A HZ3  1 
ATOM 4045 H HH2  . TRP A 1 278 ? 97.572  113.176 135.546 1.00 57.57  ? 278 TRP A HH2  1 
ATOM 4046 N N    . LEU A 1 279 ? 92.676  114.071 127.995 1.00 51.81  ? 279 LEU A N    1 
ATOM 4047 C CA   . LEU A 1 279 ? 91.941  114.347 126.770 1.00 54.40  ? 279 LEU A CA   1 
ATOM 4048 C C    . LEU A 1 279 ? 90.538  113.763 126.874 1.00 62.05  ? 279 LEU A C    1 
ATOM 4049 O O    . LEU A 1 279 ? 90.326  112.725 127.504 1.00 73.23  ? 279 LEU A O    1 
ATOM 4050 C CB   . LEU A 1 279 ? 92.678  113.758 125.568 1.00 51.93  ? 279 LEU A CB   1 
ATOM 4051 C CG   . LEU A 1 279 ? 94.027  114.382 125.189 1.00 51.00  ? 279 LEU A CG   1 
ATOM 4052 C CD1  . LEU A 1 279 ? 94.205  114.341 123.687 1.00 50.69  ? 279 LEU A CD1  1 
ATOM 4053 C CD2  . LEU A 1 279 ? 94.183  115.811 125.700 1.00 48.93  ? 279 LEU A CD2  1 
ATOM 4054 H H    . LEU A 1 279 ? 93.347  113.542 127.897 1.00 53.96  ? 279 LEU A H    1 
ATOM 4055 H HA   . LEU A 1 279 ? 91.854  115.305 126.653 1.00 54.82  ? 279 LEU A HA   1 
ATOM 4056 H HB2  . LEU A 1 279 ? 92.841  112.818 125.747 1.00 53.50  ? 279 LEU A HB2  1 
ATOM 4057 H HB3  . LEU A 1 279 ? 92.100  113.839 124.794 1.00 53.11  ? 279 LEU A HB3  1 
ATOM 4058 H HG   . LEU A 1 279 ? 94.736  113.851 125.584 1.00 53.91  ? 279 LEU A HG   1 
ATOM 4059 H HD11 . LEU A 1 279 ? 95.055  114.750 123.463 1.00 50.67  ? 279 LEU A HD11 1 
ATOM 4060 H HD12 . LEU A 1 279 ? 94.195  113.416 123.394 1.00 51.81  ? 279 LEU A HD12 1 
ATOM 4061 H HD13 . LEU A 1 279 ? 93.481  114.830 123.267 1.00 52.08  ? 279 LEU A HD13 1 
ATOM 4062 H HD21 . LEU A 1 279 ? 95.010  116.181 125.352 1.00 51.06  ? 279 LEU A HD21 1 
ATOM 4063 H HD22 . LEU A 1 279 ? 93.430  116.340 125.391 1.00 49.35  ? 279 LEU A HD22 1 
ATOM 4064 H HD23 . LEU A 1 279 ? 94.209  115.803 126.669 1.00 51.40  ? 279 LEU A HD23 1 
ATOM 4065 N N    . ALA A 1 280 ? 89.573  114.443 126.261 1.00 57.87  ? 280 ALA A N    1 
ATOM 4066 C CA   . ALA A 1 280 ? 88.173  114.065 126.387 1.00 61.62  ? 280 ALA A CA   1 
ATOM 4067 C C    . ALA A 1 280 ? 87.768  113.085 125.294 1.00 69.12  ? 280 ALA A C    1 
ATOM 4068 O O    . ALA A 1 280 ? 88.183  113.214 124.139 1.00 67.72  ? 280 ALA A O    1 
ATOM 4069 C CB   . ALA A 1 280 ? 87.277  115.303 126.330 1.00 60.53  ? 280 ALA A CB   1 
ATOM 4070 H H    . ALA A 1 280 ? 89.706  115.132 125.764 1.00 58.64  ? 280 ALA A H    1 
ATOM 4071 H HA   . ALA A 1 280 ? 88.040  113.633 127.245 1.00 61.37  ? 280 ALA A HA   1 
ATOM 4072 H HB1  . ALA A 1 280 ? 87.505  115.892 127.066 1.00 59.86  ? 280 ALA A HB1  1 
ATOM 4073 H HB2  . ALA A 1 280 ? 87.419  115.759 125.485 1.00 60.51  ? 280 ALA A HB2  1 
ATOM 4074 H HB3  . ALA A 1 280 ? 86.351  115.025 126.404 1.00 61.49  ? 280 ALA A HB3  1 
ATOM 4075 N N    . GLU A 1 281 ? 86.953  112.102 125.672 1.00 68.55  ? 281 GLU A N    1 
ATOM 4076 C CA   . GLU A 1 281 ? 86.372  111.178 124.709 1.00 65.75  ? 281 GLU A CA   1 
ATOM 4077 C C    . GLU A 1 281 ? 85.246  111.873 123.955 1.00 68.65  ? 281 GLU A C    1 
ATOM 4078 O O    . GLU A 1 281 ? 84.411  112.553 124.559 1.00 74.10  ? 281 GLU A O    1 
ATOM 4079 C CB   . GLU A 1 281 ? 85.845  109.928 125.415 1.00 69.00  ? 281 GLU A CB   1 
ATOM 4080 C CG   . GLU A 1 281 ? 85.408  108.815 124.471 1.00 71.03  ? 281 GLU A CG   1 
ATOM 4081 C CD   . GLU A 1 281 ? 86.433  107.706 124.353 1.00 74.97  ? 281 GLU A CD   1 
ATOM 4082 O OE1  . GLU A 1 281 ? 86.766  107.088 125.387 1.00 84.36  ? 281 GLU A OE1  1 
ATOM 4083 O OE2  . GLU A 1 281 ? 86.905  107.450 123.226 1.00 68.67  ? 281 GLU A OE2  1 
ATOM 4084 H H    . GLU A 1 281 ? 86.721  111.951 126.486 1.00 66.56  ? 281 GLU A H    1 
ATOM 4085 H HA   . GLU A 1 281 ? 87.049  110.907 124.071 1.00 65.04  ? 281 GLU A HA   1 
ATOM 4086 H HB2  . GLU A 1 281 ? 86.546  109.574 125.986 1.00 69.19  ? 281 GLU A HB2  1 
ATOM 4087 H HB3  . GLU A 1 281 ? 85.078  110.176 125.955 1.00 68.25  ? 281 GLU A HB3  1 
ATOM 4088 H HG2  . GLU A 1 281 ? 84.584  108.425 124.804 1.00 71.86  ? 281 GLU A HG2  1 
ATOM 4089 H HG3  . GLU A 1 281 ? 85.266  109.184 123.586 1.00 68.46  ? 281 GLU A HG3  1 
ATOM 4090 N N    . SER A 1 282 ? 85.224  111.698 122.635 1.00 65.38  ? 282 SER A N    1 
ATOM 4091 C CA   . SER A 1 282 ? 84.245  112.391 121.808 1.00 64.65  ? 282 SER A CA   1 
ATOM 4092 C C    . SER A 1 282 ? 82.828  112.033 122.237 1.00 62.27  ? 282 SER A C    1 
ATOM 4093 O O    . SER A 1 282 ? 82.490  110.856 122.394 1.00 72.93  ? 282 SER A O    1 
ATOM 4094 C CB   . SER A 1 282 ? 84.463  112.040 120.336 1.00 61.98  ? 282 SER A CB   1 
ATOM 4095 O OG   . SER A 1 282 ? 84.082  110.703 120.064 1.00 65.88  ? 282 SER A OG   1 
ATOM 4096 H H    . SER A 1 282 ? 85.760  111.187 122.199 1.00 64.83  ? 282 SER A H    1 
ATOM 4097 H HA   . SER A 1 282 ? 84.360  113.348 121.912 1.00 66.50  ? 282 SER A HA   1 
ATOM 4098 H HB2  . SER A 1 282 ? 83.932  112.638 119.787 1.00 63.99  ? 282 SER A HB2  1 
ATOM 4099 H HB3  . SER A 1 282 ? 85.404  112.150 120.126 1.00 64.49  ? 282 SER A HB3  1 
ATOM 4100 H HG   . SER A 1 282 ? 83.253  110.612 120.159 1.00 65.73  ? 282 SER A HG   1 
ATOM 4101 N N    . ALA A 1 283 ? 81.997  113.061 122.425 1.00 60.49  ? 283 ALA A N    1 
ATOM 4102 C CA   . ALA A 1 283 ? 80.626  112.852 122.873 1.00 62.79  ? 283 ALA A CA   1 
ATOM 4103 C C    . ALA A 1 283 ? 79.724  112.346 121.758 1.00 69.34  ? 283 ALA A C    1 
ATOM 4104 O O    . ALA A 1 283 ? 78.664  111.783 122.045 1.00 71.08  ? 283 ALA A O    1 
ATOM 4105 C CB   . ALA A 1 283 ? 80.062  114.151 123.450 1.00 64.49  ? 283 ALA A CB   1 
ATOM 4106 H H    . ALA A 1 283 ? 82.203  113.886 122.296 1.00 64.09  ? 283 ALA A H    1 
ATOM 4107 H HA   . ALA A 1 283 ? 80.626  112.187 123.578 1.00 63.84  ? 283 ALA A HA   1 
ATOM 4108 H HB1  . ALA A 1 283 ? 80.597  114.409 124.217 1.00 65.18  ? 283 ALA A HB1  1 
ATOM 4109 H HB2  . ALA A 1 283 ? 80.102  114.844 122.771 1.00 67.20  ? 283 ALA A HB2  1 
ATOM 4110 H HB3  . ALA A 1 283 ? 79.142  114.006 123.721 1.00 62.96  ? 283 ALA A HB3  1 
ATOM 4111 N N    . ARG A 1 284 ? 80.112  112.544 120.499 1.00 73.15  ? 284 ARG A N    1 
ATOM 4112 C CA   . ARG A 1 284 ? 79.322  112.038 119.380 1.00 78.71  ? 284 ARG A CA   1 
ATOM 4113 C C    . ARG A 1 284 ? 79.204  110.519 119.442 1.00 75.36  ? 284 ARG A C    1 
ATOM 4114 O O    . ARG A 1 284 ? 78.094  109.962 119.470 1.00 74.49  ? 284 ARG A O    1 
ATOM 4115 C CB   . ARG A 1 284 ? 79.985  112.498 118.079 1.00 80.99  ? 284 ARG A CB   1 
ATOM 4116 C CG   . ARG A 1 284 ? 79.646  111.748 116.802 1.00 77.29  ? 284 ARG A CG   1 
ATOM 4117 C CD   . ARG A 1 284 ? 78.162  111.722 116.510 1.00 76.76  ? 284 ARG A CD   1 
ATOM 4118 N NE   . ARG A 1 284 ? 77.902  111.532 115.086 1.00 80.23  ? 284 ARG A NE   1 
ATOM 4119 C CZ   . ARG A 1 284 ? 78.227  110.451 114.390 1.00 88.20  ? 284 ARG A CZ   1 
ATOM 4120 N NH1  . ARG A 1 284 ? 78.845  109.424 114.949 1.00 89.61  ? 284 ARG A NH1  1 
ATOM 4121 N NH2  . ARG A 1 284 ? 77.936  110.404 113.093 1.00 88.61  ? 284 ARG A NH2  1 
ATOM 4122 H H    . ARG A 1 284 ? 80.826  112.962 120.266 1.00 71.51  ? 284 ARG A H    1 
ATOM 4123 H HA   . ARG A 1 284 ? 78.429  112.414 119.422 1.00 77.35  ? 284 ARG A HA   1 
ATOM 4124 H HB2  . ARG A 1 284 ? 79.749  113.426 117.935 1.00 80.29  ? 284 ARG A HB2  1 
ATOM 4125 H HB3  . ARG A 1 284 ? 80.945  112.431 118.194 1.00 76.72  ? 284 ARG A HB3  1 
ATOM 4126 H HG2  . ARG A 1 284 ? 80.091  112.182 116.058 1.00 78.01  ? 284 ARG A HG2  1 
ATOM 4127 H HG3  . ARG A 1 284 ? 79.959  110.834 116.881 1.00 78.52  ? 284 ARG A HG3  1 
ATOM 4128 H HD2  . ARG A 1 284 ? 77.754  110.988 116.993 1.00 78.34  ? 284 ARG A HD2  1 
ATOM 4129 H HD3  . ARG A 1 284 ? 77.767  112.565 116.783 1.00 79.04  ? 284 ARG A HD3  1 
ATOM 4130 H HE   . ARG A 1 284 ? 77.636  112.219 114.642 1.00 81.52  ? 284 ARG A HE   1 
ATOM 4131 H HH11 . ARG A 1 284 ? 79.039  109.437 115.786 1.00 86.31  ? 284 ARG A HH11 1 
ATOM 4132 H HH12 . ARG A 1 284 ? 79.044  108.735 114.474 1.00 89.27  ? 284 ARG A HH12 1 
ATOM 4133 H HH21 . ARG A 1 284 ? 77.539  111.068 112.718 1.00 86.36  ? 284 ARG A HH21 1 
ATOM 4134 H HH22 . ARG A 1 284 ? 78.144  109.710 112.630 1.00 87.11  ? 284 ARG A HH22 1 
ATOM 4135 N N    . TRP A 1 285 ? 80.347  109.835 119.521 1.00 70.71  ? 285 TRP A N    1 
ATOM 4136 C CA   . TRP A 1 285 ? 80.345  108.380 119.591 1.00 67.28  ? 285 TRP A CA   1 
ATOM 4137 C C    . TRP A 1 285 ? 79.665  107.899 120.865 1.00 64.61  ? 285 TRP A C    1 
ATOM 4138 O O    . TRP A 1 285 ? 78.938  106.899 120.850 1.00 72.00  ? 285 TRP A O    1 
ATOM 4139 C CB   . TRP A 1 285 ? 81.781  107.859 119.525 1.00 61.73  ? 285 TRP A CB   1 
ATOM 4140 C CG   . TRP A 1 285 ? 81.899  106.391 119.775 1.00 63.02  ? 285 TRP A CG   1 
ATOM 4141 C CD1  . TRP A 1 285 ? 81.664  105.383 118.886 1.00 67.18  ? 285 TRP A CD1  1 
ATOM 4142 C CD2  . TRP A 1 285 ? 82.250  105.763 121.011 1.00 67.46  ? 285 TRP A CD2  1 
ATOM 4143 N NE1  . TRP A 1 285 ? 81.865  104.165 119.490 1.00 67.34  ? 285 TRP A NE1  1 
ATOM 4144 C CE2  . TRP A 1 285 ? 82.223  104.372 120.796 1.00 66.18  ? 285 TRP A CE2  1 
ATOM 4145 C CE3  . TRP A 1 285 ? 82.590  106.243 122.279 1.00 66.45  ? 285 TRP A CE3  1 
ATOM 4146 C CZ2  . TRP A 1 285 ? 82.523  103.456 121.801 1.00 62.39  ? 285 TRP A CZ2  1 
ATOM 4147 C CZ3  . TRP A 1 285 ? 82.888  105.334 123.274 1.00 67.97  ? 285 TRP A CZ3  1 
ATOM 4148 C CH2  . TRP A 1 285 ? 82.853  103.956 123.030 1.00 63.84  ? 285 TRP A CH2  1 
ATOM 4149 H H    . TRP A 1 285 ? 81.130  110.188 119.540 1.00 70.33  ? 285 TRP A H    1 
ATOM 4150 H HA   . TRP A 1 285 ? 79.858  108.025 118.832 1.00 70.15  ? 285 TRP A HA   1 
ATOM 4151 H HB2  . TRP A 1 285 ? 82.134  108.039 118.639 1.00 64.54  ? 285 TRP A HB2  1 
ATOM 4152 H HB3  . TRP A 1 285 ? 82.312  108.320 120.193 1.00 64.54  ? 285 TRP A HB3  1 
ATOM 4153 H HD1  . TRP A 1 285 ? 81.416  105.503 117.998 1.00 66.88  ? 285 TRP A HD1  1 
ATOM 4154 H HE1  . TRP A 1 285 ? 81.777  103.398 119.111 1.00 65.81  ? 285 TRP A HE1  1 
ATOM 4155 H HE3  . TRP A 1 285 ? 82.615  107.157 122.448 1.00 65.47  ? 285 TRP A HE3  1 
ATOM 4156 H HZ2  . TRP A 1 285 ? 82.501  102.540 121.642 1.00 62.51  ? 285 TRP A HZ2  1 
ATOM 4157 H HZ3  . TRP A 1 285 ? 83.115  105.643 124.121 1.00 66.95  ? 285 TRP A HZ3  1 
ATOM 4158 H HH2  . TRP A 1 285 ? 83.059  103.368 123.720 1.00 63.47  ? 285 TRP A HH2  1 
ATOM 4159 N N    . LEU A 1 286 ? 79.891  108.600 121.977 1.00 61.90  ? 286 LEU A N    1 
ATOM 4160 C CA   . LEU A 1 286 ? 79.268  108.210 123.235 1.00 68.28  ? 286 LEU A CA   1 
ATOM 4161 C C    . LEU A 1 286 ? 77.751  108.278 123.138 1.00 67.28  ? 286 LEU A C    1 
ATOM 4162 O O    . LEU A 1 286 ? 77.049  107.363 123.585 1.00 75.27  ? 286 LEU A O    1 
ATOM 4163 C CB   . LEU A 1 286 ? 79.764  109.116 124.360 1.00 69.94  ? 286 LEU A CB   1 
ATOM 4164 C CG   . LEU A 1 286 ? 81.158  108.827 124.914 1.00 70.99  ? 286 LEU A CG   1 
ATOM 4165 C CD1  . LEU A 1 286 ? 81.601  109.960 125.829 1.00 71.00  ? 286 LEU A CD1  1 
ATOM 4166 C CD2  . LEU A 1 286 ? 81.188  107.494 125.643 1.00 74.66  ? 286 LEU A CD2  1 
ATOM 4167 H H    . LEU A 1 286 ? 80.391  109.298 122.026 1.00 66.79  ? 286 LEU A H    1 
ATOM 4168 H HA   . LEU A 1 286 ? 79.518  107.296 123.444 1.00 68.76  ? 286 LEU A HA   1 
ATOM 4169 H HB2  . LEU A 1 286 ? 79.773  110.028 124.028 1.00 70.90  ? 286 LEU A HB2  1 
ATOM 4170 H HB3  . LEU A 1 286 ? 79.140  109.052 125.100 1.00 67.45  ? 286 LEU A HB3  1 
ATOM 4171 H HG   . LEU A 1 286 ? 81.786  108.779 124.176 1.00 69.44  ? 286 LEU A HG   1 
ATOM 4172 H HD11 . LEU A 1 286 ? 80.980  110.025 126.572 1.00 69.26  ? 286 LEU A HD11 1 
ATOM 4173 H HD12 . LEU A 1 286 ? 82.493  109.771 126.158 1.00 70.66  ? 286 LEU A HD12 1 
ATOM 4174 H HD13 . LEU A 1 286 ? 81.602  110.789 125.326 1.00 69.23  ? 286 LEU A HD13 1 
ATOM 4175 H HD21 . LEU A 1 286 ? 80.463  107.471 126.288 1.00 72.04  ? 286 LEU A HD21 1 
ATOM 4176 H HD22 . LEU A 1 286 ? 81.080  106.779 124.997 1.00 71.84  ? 286 LEU A HD22 1 
ATOM 4177 H HD23 . LEU A 1 286 ? 82.040  107.402 126.097 1.00 73.61  ? 286 LEU A HD23 1 
ATOM 4178 N N    . LEU A 1 287 ? 77.226  109.355 122.550 1.00 62.07  ? 287 LEU A N    1 
ATOM 4179 C CA   . LEU A 1 287 ? 75.781  109.537 122.508 1.00 67.66  ? 287 LEU A CA   1 
ATOM 4180 C C    . LEU A 1 287 ? 75.124  108.555 121.549 1.00 76.72  ? 287 LEU A C    1 
ATOM 4181 O O    . LEU A 1 287 ? 74.068  107.994 121.863 1.00 78.45  ? 287 LEU A O    1 
ATOM 4182 C CB   . LEU A 1 287 ? 75.436  110.975 122.119 1.00 73.23  ? 287 LEU A CB   1 
ATOM 4183 C CG   . LEU A 1 287 ? 75.401  111.977 123.276 1.00 80.53  ? 287 LEU A CG   1 
ATOM 4184 C CD1  . LEU A 1 287 ? 75.526  113.409 122.762 1.00 87.91  ? 287 LEU A CD1  1 
ATOM 4185 C CD2  . LEU A 1 287 ? 74.140  111.797 124.113 1.00 79.58  ? 287 LEU A CD2  1 
ATOM 4186 H H    . LEU A 1 287 ? 77.679  109.985 122.180 1.00 67.12  ? 287 LEU A H    1 
ATOM 4187 H HA   . LEU A 1 287 ? 75.421  109.375 123.395 1.00 69.31  ? 287 LEU A HA   1 
ATOM 4188 H HB2  . LEU A 1 287 ? 76.094  111.287 121.478 1.00 73.95  ? 287 LEU A HB2  1 
ATOM 4189 H HB3  . LEU A 1 287 ? 74.556  110.976 121.710 1.00 74.29  ? 287 LEU A HB3  1 
ATOM 4190 H HG   . LEU A 1 287 ? 76.162  111.808 123.854 1.00 76.84  ? 287 LEU A HG   1 
ATOM 4191 H HD11 . LEU A 1 287 ? 75.659  114.005 123.516 1.00 82.94  ? 287 LEU A HD11 1 
ATOM 4192 H HD12 . LEU A 1 287 ? 76.282  113.465 122.158 1.00 81.59  ? 287 LEU A HD12 1 
ATOM 4193 H HD13 . LEU A 1 287 ? 74.710  113.648 122.293 1.00 84.96  ? 287 LEU A HD13 1 
ATOM 4194 H HD21 . LEU A 1 287 ? 74.120  112.476 124.804 1.00 80.34  ? 287 LEU A HD21 1 
ATOM 4195 H HD22 . LEU A 1 287 ? 73.362  111.882 123.540 1.00 77.69  ? 287 LEU A HD22 1 
ATOM 4196 H HD23 . LEU A 1 287 ? 74.158  110.916 124.518 1.00 74.87  ? 287 LEU A HD23 1 
ATOM 4197 N N    . ILE A 1 288 ? 75.720  108.327 120.375 1.00 73.58  ? 288 ILE A N    1 
ATOM 4198 C CA   . ILE A 1 288 ? 75.056  107.416 119.441 1.00 68.33  ? 288 ILE A CA   1 
ATOM 4199 C C    . ILE A 1 288 ? 75.049  105.988 119.979 1.00 72.37  ? 288 ILE A C    1 
ATOM 4200 O O    . ILE A 1 288 ? 74.093  105.239 119.747 1.00 74.77  ? 288 ILE A O    1 
ATOM 4201 C CB   . ILE A 1 288 ? 75.687  107.483 118.036 1.00 63.79  ? 288 ILE A CB   1 
ATOM 4202 C CG1  . ILE A 1 288 ? 77.072  106.831 118.012 1.00 65.97  ? 288 ILE A CG1  1 
ATOM 4203 C CG2  . ILE A 1 288 ? 75.743  108.917 117.544 1.00 67.45  ? 288 ILE A CG2  1 
ATOM 4204 C CD1  . ILE A 1 288 ? 77.699  106.829 116.640 1.00 64.54  ? 288 ILE A CD1  1 
ATOM 4205 H H    . ILE A 1 288 ? 76.466  108.665 120.109 1.00 71.38  ? 288 ILE A H    1 
ATOM 4206 H HA   . ILE A 1 288 ? 74.131  107.693 119.354 1.00 69.08  ? 288 ILE A HA   1 
ATOM 4207 H HB   . ILE A 1 288 ? 75.113  106.987 117.432 1.00 67.94  ? 288 ILE A HB   1 
ATOM 4208 H HG12 . ILE A 1 288 ? 77.661  107.316 118.611 1.00 68.02  ? 288 ILE A HG12 1 
ATOM 4209 H HG13 . ILE A 1 288 ? 76.999  105.907 118.292 1.00 68.47  ? 288 ILE A HG13 1 
ATOM 4210 H HG21 . ILE A 1 288 ? 75.723  108.914 116.575 1.00 69.90  ? 288 ILE A HG21 1 
ATOM 4211 H HG22 . ILE A 1 288 ? 74.975  109.399 117.889 1.00 68.18  ? 288 ILE A HG22 1 
ATOM 4212 H HG23 . ILE A 1 288 ? 76.561  109.326 117.859 1.00 69.19  ? 288 ILE A HG23 1 
ATOM 4213 H HD11 . ILE A 1 288 ? 78.536  106.340 116.673 1.00 65.72  ? 288 ILE A HD11 1 
ATOM 4214 H HD12 . ILE A 1 288 ? 77.091  106.404 116.015 1.00 68.06  ? 288 ILE A HD12 1 
ATOM 4215 H HD13 . ILE A 1 288 ? 77.859  107.743 116.371 1.00 69.18  ? 288 ILE A HD13 1 
ATOM 4216 N N    . THR A 1 289 ? 76.097  105.582 120.696 1.00 69.18  ? 289 THR A N    1 
ATOM 4217 C CA   . THR A 1 289 ? 76.240  104.203 121.149 1.00 65.42  ? 289 THR A CA   1 
ATOM 4218 C C    . THR A 1 289 ? 75.503  103.917 122.459 1.00 68.38  ? 289 THR A C    1 
ATOM 4219 O O    . THR A 1 289 ? 75.809  102.917 123.118 1.00 72.18  ? 289 THR A O    1 
ATOM 4220 C CB   . THR A 1 289 ? 77.722  103.852 121.309 1.00 66.74  ? 289 THR A CB   1 
ATOM 4221 O OG1  . THR A 1 289 ? 78.481  104.472 120.263 1.00 62.30  ? 289 THR A OG1  1 
ATOM 4222 C CG2  . THR A 1 289 ? 77.927  102.343 121.247 1.00 73.42  ? 289 THR A CG2  1 
ATOM 4223 H H    . THR A 1 289 ? 76.744  106.095 120.935 1.00 69.65  ? 289 THR A H    1 
ATOM 4224 H HA   . THR A 1 289 ? 75.867  103.617 120.472 1.00 66.86  ? 289 THR A HA   1 
ATOM 4225 H HB   . THR A 1 289 ? 78.039  104.168 122.169 1.00 66.79  ? 289 THR A HB   1 
ATOM 4226 H HG1  . THR A 1 289 ? 78.464  105.307 120.352 1.00 66.71  ? 289 THR A HG1  1 
ATOM 4227 H HG21 . THR A 1 289 ? 77.688  101.938 122.095 1.00 72.15  ? 289 THR A HG21 1 
ATOM 4228 H HG22 . THR A 1 289 ? 77.373  101.960 120.548 1.00 73.59  ? 289 THR A HG22 1 
ATOM 4229 H HG23 . THR A 1 289 ? 78.857  102.143 121.058 1.00 69.45  ? 289 THR A HG23 1 
ATOM 4230 N N    . GLY A 1 290 ? 74.548  104.755 122.855 1.00 71.30  ? 290 GLY A N    1 
ATOM 4231 C CA   . GLY A 1 290 ? 73.786  104.513 124.062 1.00 77.90  ? 290 GLY A CA   1 
ATOM 4232 C C    . GLY A 1 290 ? 74.421  105.018 125.338 1.00 79.22  ? 290 GLY A C    1 
ATOM 4233 O O    . GLY A 1 290 ? 73.802  104.904 126.404 1.00 77.94  ? 290 GLY A O    1 
ATOM 4234 H H    . GLY A 1 290 ? 74.326  105.473 122.437 1.00 71.24  ? 290 GLY A H    1 
ATOM 4235 H HA2  . GLY A 1 290 ? 72.916  104.931 123.974 1.00 75.47  ? 290 GLY A HA2  1 
ATOM 4236 H HA3  . GLY A 1 290 ? 73.648  103.557 124.159 1.00 76.55  ? 290 GLY A HA3  1 
ATOM 4237 N N    . ARG A 1 291 ? 75.630  105.570 125.271 1.00 77.55  ? 291 ARG A N    1 
ATOM 4238 C CA   . ARG A 1 291 ? 76.306  106.125 126.443 1.00 76.50  ? 291 ARG A CA   1 
ATOM 4239 C C    . ARG A 1 291 ? 75.893  107.586 126.571 1.00 78.37  ? 291 ARG A C    1 
ATOM 4240 O O    . ARG A 1 291 ? 76.473  108.468 125.932 1.00 76.93  ? 291 ARG A O    1 
ATOM 4241 C CB   . ARG A 1 291 ? 77.817  105.972 126.312 1.00 74.23  ? 291 ARG A CB   1 
ATOM 4242 C CG   . ARG A 1 291 ? 78.360  104.670 126.893 1.00 70.90  ? 291 ARG A CG   1 
ATOM 4243 C CD   . ARG A 1 291 ? 79.654  104.226 126.216 1.00 73.85  ? 291 ARG A CD   1 
ATOM 4244 N NE   . ARG A 1 291 ? 79.643  102.800 125.902 1.00 77.13  ? 291 ARG A NE   1 
ATOM 4245 C CZ   . ARG A 1 291 ? 79.771  102.279 124.688 1.00 76.74  ? 291 ARG A CZ   1 
ATOM 4246 N NH1  . ARG A 1 291 ? 79.918  103.039 123.614 1.00 68.12  ? 291 ARG A NH1  1 
ATOM 4247 N NH2  . ARG A 1 291 ? 79.754  100.957 124.546 1.00 77.18  ? 291 ARG A NH2  1 
ATOM 4248 H H    . ARG A 1 291 ? 76.088  105.637 124.547 1.00 74.63  ? 291 ARG A H    1 
ATOM 4249 H HA   . ARG A 1 291 ? 76.016  105.651 127.238 1.00 75.45  ? 291 ARG A HA   1 
ATOM 4250 H HB2  . ARG A 1 291 ? 78.048  106.003 125.371 1.00 73.90  ? 291 ARG A HB2  1 
ATOM 4251 H HB3  . ARG A 1 291 ? 78.245  106.705 126.780 1.00 74.49  ? 291 ARG A HB3  1 
ATOM 4252 H HG2  . ARG A 1 291 ? 78.543  104.796 127.837 1.00 72.62  ? 291 ARG A HG2  1 
ATOM 4253 H HG3  . ARG A 1 291 ? 77.701  103.968 126.772 1.00 71.94  ? 291 ARG A HG3  1 
ATOM 4254 H HD2  . ARG A 1 291 ? 79.779  104.734 125.402 1.00 72.95  ? 291 ARG A HD2  1 
ATOM 4255 H HD3  . ARG A 1 291 ? 80.395  104.391 126.818 1.00 73.23  ? 291 ARG A HD3  1 
ATOM 4256 H HE   . ARG A 1 291 ? 79.553  102.252 126.559 1.00 76.57  ? 291 ARG A HE   1 
ATOM 4257 H HH11 . ARG A 1 291 ? 79.932  103.894 123.680 1.00 69.25  ? 291 ARG A HH11 1 
ATOM 4258 H HH12 . ARG A 1 291 ? 79.998  102.671 122.841 1.00 68.52  ? 291 ARG A HH12 1 
ATOM 4259 H HH21 . ARG A 1 291 ? 79.660  100.452 125.236 1.00 75.34  ? 291 ARG A HH21 1 
ATOM 4260 H HH22 . ARG A 1 291 ? 79.836  100.606 123.765 1.00 74.23  ? 291 ARG A HH22 1 
ATOM 4261 N N    . LEU A 1 292 ? 74.887  107.845 127.405 1.00 81.25  ? 292 LEU A N    1 
ATOM 4262 C CA   . LEU A 1 292 ? 74.303  109.173 127.550 1.00 81.19  ? 292 LEU A CA   1 
ATOM 4263 C C    . LEU A 1 292 ? 74.904  109.958 128.710 1.00 82.38  ? 292 LEU A C    1 
ATOM 4264 O O    . LEU A 1 292 ? 75.315  111.109 128.534 1.00 82.22  ? 292 LEU A O    1 
ATOM 4265 C CB   . LEU A 1 292 ? 72.785  109.054 127.741 1.00 79.29  ? 292 LEU A CB   1 
ATOM 4266 C CG   . LEU A 1 292 ? 72.018  108.310 126.645 1.00 86.55  ? 292 LEU A CG   1 
ATOM 4267 C CD1  . LEU A 1 292 ? 70.577  108.070 127.069 1.00 91.05  ? 292 LEU A CD1  1 
ATOM 4268 C CD2  . LEU A 1 292 ? 72.071  109.072 125.331 1.00 85.65  ? 292 LEU A CD2  1 
ATOM 4269 H H    . LEU A 1 292 ? 74.520  107.251 127.909 1.00 80.12  ? 292 LEU A H    1 
ATOM 4270 H HA   . LEU A 1 292 ? 74.462  109.676 126.736 1.00 80.11  ? 292 LEU A HA   1 
ATOM 4271 H HB2  . LEU A 1 292 ? 72.619  108.588 128.576 1.00 80.75  ? 292 LEU A HB2  1 
ATOM 4272 H HB3  . LEU A 1 292 ? 72.415  109.949 127.794 1.00 79.57  ? 292 LEU A HB3  1 
ATOM 4273 H HG   . LEU A 1 292 ? 72.433  107.445 126.503 1.00 83.47  ? 292 LEU A HG   1 
ATOM 4274 H HD11 . LEU A 1 292 ? 70.109  107.613 126.353 1.00 88.50  ? 292 LEU A HD11 1 
ATOM 4275 H HD12 . LEU A 1 292 ? 70.571  107.523 127.870 1.00 89.35  ? 292 LEU A HD12 1 
ATOM 4276 H HD13 . LEU A 1 292 ? 70.154  108.924 127.249 1.00 89.10  ? 292 LEU A HD13 1 
ATOM 4277 H HD21 . LEU A 1 292 ? 71.446  108.669 124.708 1.00 84.49  ? 292 LEU A HD21 1 
ATOM 4278 H HD22 . LEU A 1 292 ? 71.826  109.997 125.493 1.00 84.18  ? 292 LEU A HD22 1 
ATOM 4279 H HD23 . LEU A 1 292 ? 72.972  109.025 124.976 1.00 81.21  ? 292 LEU A HD23 1 
ATOM 4280 N N    . ASP A 1 293 ? 74.959  109.355 129.901 1.00 82.28  ? 293 ASP A N    1 
ATOM 4281 C CA   . ASP A 1 293 ? 75.434  110.080 131.075 1.00 76.46  ? 293 ASP A CA   1 
ATOM 4282 C C    . ASP A 1 293 ? 76.885  110.516 130.910 1.00 73.29  ? 293 ASP A C    1 
ATOM 4283 O O    . ASP A 1 293 ? 77.236  111.660 131.220 1.00 80.91  ? 293 ASP A O    1 
ATOM 4284 C CB   . ASP A 1 293 ? 75.276  109.212 132.323 1.00 77.57  ? 293 ASP A CB   1 
ATOM 4285 C CG   . ASP A 1 293 ? 74.958  110.024 133.563 1.00 86.57  ? 293 ASP A CG   1 
ATOM 4286 O OD1  . ASP A 1 293 ? 75.370  111.201 133.625 1.00 95.63  ? 293 ASP A OD1  1 
ATOM 4287 O OD2  . ASP A 1 293 ? 74.296  109.485 134.475 1.00 86.28  ? 293 ASP A OD2  1 
ATOM 4288 H H    . ASP A 1 293 ? 74.730  108.540 130.051 1.00 81.94  ? 293 ASP A H    1 
ATOM 4289 H HA   . ASP A 1 293 ? 74.894  110.877 131.193 1.00 79.42  ? 293 ASP A HA   1 
ATOM 4290 H HB2  . ASP A 1 293 ? 74.550  108.584 132.182 1.00 79.54  ? 293 ASP A HB2  1 
ATOM 4291 H HB3  . ASP A 1 293 ? 76.103  108.731 132.481 1.00 79.52  ? 293 ASP A HB3  1 
ATOM 4292 N N    . ARG A 1 294 ? 77.745  109.616 130.428 1.00 68.63  ? 294 ARG A N    1 
ATOM 4293 C CA   . ARG A 1 294 ? 79.154  109.961 130.270 1.00 73.37  ? 294 ARG A CA   1 
ATOM 4294 C C    . ARG A 1 294 ? 79.342  111.032 129.202 1.00 72.74  ? 294 ARG A C    1 
ATOM 4295 O O    . ARG A 1 294 ? 80.169  111.938 129.363 1.00 78.43  ? 294 ARG A O    1 
ATOM 4296 C CB   . ARG A 1 294 ? 79.964  108.710 129.932 1.00 80.50  ? 294 ARG A CB   1 
ATOM 4297 C CG   . ARG A 1 294 ? 81.447  108.975 129.731 1.00 86.56  ? 294 ARG A CG   1 
ATOM 4298 C CD   . ARG A 1 294 ? 82.309  107.868 130.323 1.00 84.02  ? 294 ARG A CD   1 
ATOM 4299 N NE   . ARG A 1 294 ? 82.215  106.624 129.567 1.00 86.80  ? 294 ARG A NE   1 
ATOM 4300 C CZ   . ARG A 1 294 ? 81.429  105.601 129.879 1.00 89.44  ? 294 ARG A CZ   1 
ATOM 4301 N NH1  . ARG A 1 294 ? 80.636  105.631 130.939 1.00 91.77  ? 294 ARG A NH1  1 
ATOM 4302 N NH2  . ARG A 1 294 ? 81.442  104.516 129.110 1.00 82.46  ? 294 ARG A NH2  1 
ATOM 4303 H H    . ARG A 1 294 ? 77.541  108.815 130.191 1.00 74.88  ? 294 ARG A H    1 
ATOM 4304 H HA   . ARG A 1 294 ? 79.486  110.314 131.110 1.00 76.73  ? 294 ARG A HA   1 
ATOM 4305 H HB2  . ARG A 1 294 ? 79.869  108.077 130.660 1.00 80.82  ? 294 ARG A HB2  1 
ATOM 4306 H HB3  . ARG A 1 294 ? 79.617  108.323 129.113 1.00 79.44  ? 294 ARG A HB3  1 
ATOM 4307 H HG2  . ARG A 1 294 ? 81.636  109.030 128.782 1.00 83.10  ? 294 ARG A HG2  1 
ATOM 4308 H HG3  . ARG A 1 294 ? 81.684  109.807 130.169 1.00 84.93  ? 294 ARG A HG3  1 
ATOM 4309 H HD2  . ARG A 1 294 ? 83.236  108.153 130.307 1.00 83.47  ? 294 ARG A HD2  1 
ATOM 4310 H HD3  . ARG A 1 294 ? 82.036  107.702 131.238 1.00 82.53  ? 294 ARG A HD3  1 
ATOM 4311 H HE   . ARG A 1 294 ? 82.712  106.545 128.870 1.00 84.65  ? 294 ARG A HE   1 
ATOM 4312 H HH11 . ARG A 1 294 ? 80.614  106.322 131.448 1.00 88.80  ? 294 ARG A HH11 1 
ATOM 4313 H HH12 . ARG A 1 294 ? 80.137  104.953 131.118 1.00 89.18  ? 294 ARG A HH12 1 
ATOM 4314 H HH21 . ARG A 1 294 ? 81.954  104.485 128.420 1.00 81.21  ? 294 ARG A HH21 1 
ATOM 4315 H HH22 . ARG A 1 294 ? 80.937  103.847 129.302 1.00 82.76  ? 294 ARG A HH22 1 
ATOM 4316 N N    . GLY A 1 295 ? 78.589  110.946 128.105 1.00 67.90  ? 295 GLY A N    1 
ATOM 4317 C CA   . GLY A 1 295 ? 78.664  111.985 127.092 1.00 69.34  ? 295 GLY A CA   1 
ATOM 4318 C C    . GLY A 1 295 ? 78.233  113.339 127.622 1.00 68.51  ? 295 GLY A C    1 
ATOM 4319 O O    . GLY A 1 295 ? 78.864  114.359 127.337 1.00 77.57  ? 295 GLY A O    1 
ATOM 4320 H H    . GLY A 1 295 ? 78.038  110.308 127.930 1.00 72.78  ? 295 GLY A H    1 
ATOM 4321 H HA2  . GLY A 1 295 ? 79.577  112.057 126.770 1.00 70.97  ? 295 GLY A HA2  1 
ATOM 4322 H HA3  . GLY A 1 295 ? 78.092  111.750 126.345 1.00 72.47  ? 295 GLY A HA3  1 
ATOM 4323 N N    . LEU A 1 296 ? 77.150  113.366 128.402 1.00 68.70  ? 296 LEU A N    1 
ATOM 4324 C CA   . LEU A 1 296 ? 76.704  114.615 129.010 1.00 69.28  ? 296 LEU A CA   1 
ATOM 4325 C C    . LEU A 1 296 ? 77.756  115.168 129.963 1.00 73.62  ? 296 LEU A C    1 
ATOM 4326 O O    . LEU A 1 296 ? 78.016  116.379 129.986 1.00 73.57  ? 296 LEU A O    1 
ATOM 4327 C CB   . LEU A 1 296 ? 75.381  114.387 129.740 1.00 70.45  ? 296 LEU A CB   1 
ATOM 4328 C CG   . LEU A 1 296 ? 74.647  115.628 130.250 1.00 77.60  ? 296 LEU A CG   1 
ATOM 4329 C CD1  . LEU A 1 296 ? 73.144  115.453 130.103 1.00 86.07  ? 296 LEU A CD1  1 
ATOM 4330 C CD2  . LEU A 1 296 ? 75.012  115.909 131.699 1.00 77.45  ? 296 LEU A CD2  1 
ATOM 4331 H H    . LEU A 1 296 ? 76.664  112.682 128.593 1.00 72.39  ? 296 LEU A H    1 
ATOM 4332 H HA   . LEU A 1 296 ? 76.555  115.272 128.312 1.00 69.96  ? 296 LEU A HA   1 
ATOM 4333 H HB2  . LEU A 1 296 ? 74.778  113.929 129.133 1.00 73.32  ? 296 LEU A HB2  1 
ATOM 4334 H HB3  . LEU A 1 296 ? 75.554  113.817 130.505 1.00 73.27  ? 296 LEU A HB3  1 
ATOM 4335 H HG   . LEU A 1 296 ? 74.914  116.394 129.719 1.00 76.37  ? 296 LEU A HG   1 
ATOM 4336 H HD11 . LEU A 1 296 ? 72.866  114.675 130.611 1.00 81.21  ? 296 LEU A HD11 1 
ATOM 4337 H HD12 . LEU A 1 296 ? 72.699  116.246 130.442 1.00 81.59  ? 296 LEU A HD12 1 
ATOM 4338 H HD13 . LEU A 1 296 ? 72.930  115.329 129.165 1.00 81.98  ? 296 LEU A HD13 1 
ATOM 4339 H HD21 . LEU A 1 296 ? 74.392  116.563 132.056 1.00 78.29  ? 296 LEU A HD21 1 
ATOM 4340 H HD22 . LEU A 1 296 ? 74.948  115.086 132.209 1.00 75.78  ? 296 LEU A HD22 1 
ATOM 4341 H HD23 . LEU A 1 296 ? 75.918  116.252 131.737 1.00 76.89  ? 296 LEU A HD23 1 
ATOM 4342 N N    . ARG A 1 297 ? 78.369  114.294 130.764 1.00 73.95  ? 297 ARG A N    1 
ATOM 4343 C CA   . ARG A 1 297 ? 79.417  114.732 131.679 1.00 70.02  ? 297 ARG A CA   1 
ATOM 4344 C C    . ARG A 1 297 ? 80.594  115.328 130.919 1.00 69.27  ? 297 ARG A C    1 
ATOM 4345 O O    . ARG A 1 297 ? 81.131  116.372 131.305 1.00 73.65  ? 297 ARG A O    1 
ATOM 4346 C CB   . ARG A 1 297 ? 79.874  113.555 132.541 1.00 72.90  ? 297 ARG A CB   1 
ATOM 4347 C CG   . ARG A 1 297 ? 80.317  113.929 133.945 1.00 79.71  ? 297 ARG A CG   1 
ATOM 4348 C CD   . ARG A 1 297 ? 80.538  112.685 134.794 1.00 81.89  ? 297 ARG A CD   1 
ATOM 4349 N NE   . ARG A 1 297 ? 81.351  111.691 134.101 1.00 85.76  ? 297 ARG A NE   1 
ATOM 4350 C CZ   . ARG A 1 297 ? 81.270  110.381 134.296 1.00 86.81  ? 297 ARG A CZ   1 
ATOM 4351 N NH1  . ARG A 1 297 ? 80.425  109.860 135.172 1.00 86.09  ? 297 ARG A NH1  1 
ATOM 4352 N NH2  . ARG A 1 297 ? 82.056  109.572 133.592 1.00 82.20  ? 297 ARG A NH2  1 
ATOM 4353 H H    . ARG A 1 297 ? 78.197  113.452 130.795 1.00 74.87  ? 297 ARG A H    1 
ATOM 4354 H HA   . ARG A 1 297 ? 79.060  115.416 132.267 1.00 71.81  ? 297 ARG A HA   1 
ATOM 4355 H HB2  . ARG A 1 297 ? 79.139  112.927 132.623 1.00 74.89  ? 297 ARG A HB2  1 
ATOM 4356 H HB3  . ARG A 1 297 ? 80.623  113.125 132.099 1.00 74.66  ? 297 ARG A HB3  1 
ATOM 4357 H HG2  . ARG A 1 297 ? 81.152  114.421 133.899 1.00 79.51  ? 297 ARG A HG2  1 
ATOM 4358 H HG3  . ARG A 1 297 ? 79.630  114.468 134.366 1.00 78.45  ? 297 ARG A HG3  1 
ATOM 4359 H HD2  . ARG A 1 297 ? 80.995  112.934 135.612 1.00 82.01  ? 297 ARG A HD2  1 
ATOM 4360 H HD3  . ARG A 1 297 ? 79.676  112.290 134.998 1.00 80.73  ? 297 ARG A HD3  1 
ATOM 4361 H HE   . ARG A 1 297 ? 81.935  111.975 133.538 1.00 83.15  ? 297 ARG A HE   1 
ATOM 4362 H HH11 . ARG A 1 297 ? 79.910  110.369 135.634 1.00 84.65  ? 297 ARG A HH11 1 
ATOM 4363 H HH12 . ARG A 1 297 ? 80.393  109.007 135.279 1.00 85.84  ? 297 ARG A HH12 1 
ATOM 4364 H HH21 . ARG A 1 297 ? 82.609  109.899 133.019 1.00 83.35  ? 297 ARG A HH21 1 
ATOM 4365 H HH22 . ARG A 1 297 ? 82.013  108.721 133.709 1.00 81.77  ? 297 ARG A HH22 1 
ATOM 4366 N N    . GLU A 1 298 ? 81.009  114.677 129.830 1.00 65.50  ? 298 GLU A N    1 
ATOM 4367 C CA   . GLU A 1 298 ? 82.122  115.191 129.040 1.00 62.94  ? 298 GLU A CA   1 
ATOM 4368 C C    . GLU A 1 298 ? 81.767  116.527 128.399 1.00 61.57  ? 298 GLU A C    1 
ATOM 4369 O O    . GLU A 1 298 ? 82.604  117.436 128.331 1.00 67.58  ? 298 GLU A O    1 
ATOM 4370 C CB   . GLU A 1 298 ? 82.517  114.173 127.971 1.00 67.09  ? 298 GLU A CB   1 
ATOM 4371 C CG   . GLU A 1 298 ? 83.991  114.200 127.614 1.00 71.85  ? 298 GLU A CG   1 
ATOM 4372 C CD   . GLU A 1 298 ? 84.863  113.636 128.719 1.00 80.60  ? 298 GLU A CD   1 
ATOM 4373 O OE1  . GLU A 1 298 ? 84.310  113.065 129.682 1.00 84.90  ? 298 GLU A OE1  1 
ATOM 4374 O OE2  . GLU A 1 298 ? 86.101  113.766 128.628 1.00 76.01  ? 298 GLU A OE2  1 
ATOM 4375 H H    . GLU A 1 298 ? 80.666  113.946 129.533 1.00 69.72  ? 298 GLU A H    1 
ATOM 4376 H HA   . GLU A 1 298 ? 82.885  115.331 129.622 1.00 67.94  ? 298 GLU A HA   1 
ATOM 4377 H HB2  . GLU A 1 298 ? 82.304  113.283 128.291 1.00 70.48  ? 298 GLU A HB2  1 
ATOM 4378 H HB3  . GLU A 1 298 ? 82.014  114.360 127.162 1.00 69.04  ? 298 GLU A HB3  1 
ATOM 4379 H HG2  . GLU A 1 298 ? 84.135  113.669 126.816 1.00 71.27  ? 298 GLU A HG2  1 
ATOM 4380 H HG3  . GLU A 1 298 ? 84.262  115.118 127.457 1.00 69.96  ? 298 GLU A HG3  1 
ATOM 4381 N N    . LEU A 1 299 ? 80.533  116.657 127.910 1.00 65.08  ? 299 LEU A N    1 
ATOM 4382 C CA   . LEU A 1 299 ? 80.101  117.922 127.326 1.00 63.48  ? 299 LEU A CA   1 
ATOM 4383 C C    . LEU A 1 299 ? 80.139  119.041 128.357 1.00 61.88  ? 299 LEU A C    1 
ATOM 4384 O O    . LEU A 1 299 ? 80.608  120.148 128.067 1.00 67.76  ? 299 LEU A O    1 
ATOM 4385 C CB   . LEU A 1 299 ? 78.694  117.773 126.746 1.00 69.39  ? 299 LEU A CB   1 
ATOM 4386 C CG   . LEU A 1 299 ? 78.390  118.591 125.489 1.00 66.38  ? 299 LEU A CG   1 
ATOM 4387 C CD1  . LEU A 1 299 ? 79.253  118.142 124.317 1.00 65.67  ? 299 LEU A CD1  1 
ATOM 4388 C CD2  . LEU A 1 299 ? 76.914  118.504 125.135 1.00 74.57  ? 299 LEU A CD2  1 
ATOM 4389 H H    . LEU A 1 299 ? 79.937  116.037 127.905 1.00 68.89  ? 299 LEU A H    1 
ATOM 4390 H HA   . LEU A 1 299 ? 80.705  118.159 126.606 1.00 64.44  ? 299 LEU A HA   1 
ATOM 4391 H HB2  . LEU A 1 299 ? 78.553  116.840 126.522 1.00 69.89  ? 299 LEU A HB2  1 
ATOM 4392 H HB3  . LEU A 1 299 ? 78.055  118.040 127.425 1.00 68.42  ? 299 LEU A HB3  1 
ATOM 4393 H HG   . LEU A 1 299 ? 78.593  119.519 125.675 1.00 66.85  ? 299 LEU A HG   1 
ATOM 4394 H HD11 . LEU A 1 299 ? 79.220  117.175 124.255 1.00 67.88  ? 299 LEU A HD11 1 
ATOM 4395 H HD12 . LEU A 1 299 ? 78.908  118.538 123.501 1.00 67.36  ? 299 LEU A HD12 1 
ATOM 4396 H HD13 . LEU A 1 299 ? 80.166  118.434 124.465 1.00 66.21  ? 299 LEU A HD13 1 
ATOM 4397 H HD21 . LEU A 1 299 ? 76.639  117.573 125.147 1.00 74.17  ? 299 LEU A HD21 1 
ATOM 4398 H HD22 . LEU A 1 299 ? 76.407  119.008 125.788 1.00 70.41  ? 299 LEU A HD22 1 
ATOM 4399 H HD23 . LEU A 1 299 ? 76.777  118.879 124.251 1.00 75.70  ? 299 LEU A HD23 1 
ATOM 4400 N N    . GLN A 1 300 ? 79.651  118.771 129.571 1.00 56.41  ? 300 GLN A N    1 
ATOM 4401 C CA   . GLN A 1 300 ? 79.706  119.781 130.624 1.00 61.89  ? 300 GLN A CA   1 
ATOM 4402 C C    . GLN A 1 300 ? 81.147  120.121 130.986 1.00 65.89  ? 300 GLN A C    1 
ATOM 4403 O O    . GLN A 1 300 ? 81.475  121.287 131.232 1.00 64.04  ? 300 GLN A O    1 
ATOM 4404 C CB   . GLN A 1 300 ? 78.939  119.302 131.856 1.00 64.98  ? 300 GLN A CB   1 
ATOM 4405 C CG   . GLN A 1 300 ? 77.506  119.810 131.919 1.00 74.29  ? 300 GLN A CG   1 
ATOM 4406 C CD   . GLN A 1 300 ? 76.561  118.835 132.591 1.00 79.06  ? 300 GLN A CD   1 
ATOM 4407 O OE1  . GLN A 1 300 ? 76.986  117.945 133.329 1.00 82.43  ? 300 GLN A OE1  1 
ATOM 4408 N NE2  . GLN A 1 300 ? 75.267  119.003 132.345 1.00 75.37  ? 300 GLN A NE2  1 
ATOM 4409 H H    . GLN A 1 300 ? 79.291  118.026 129.803 1.00 63.22  ? 300 GLN A H    1 
ATOM 4410 H HA   . GLN A 1 300 ? 79.281  120.592 130.303 1.00 64.04  ? 300 GLN A HA   1 
ATOM 4411 H HB2  . GLN A 1 300 ? 78.911  118.332 131.851 1.00 67.61  ? 300 GLN A HB2  1 
ATOM 4412 H HB3  . GLN A 1 300 ? 79.399  119.614 132.651 1.00 66.90  ? 300 GLN A HB3  1 
ATOM 4413 H HG2  . GLN A 1 300 ? 77.487  120.639 132.422 1.00 72.64  ? 300 GLN A HG2  1 
ATOM 4414 H HG3  . GLN A 1 300 ? 77.185  119.963 131.017 1.00 71.25  ? 300 GLN A HG3  1 
ATOM 4415 H HE21 . GLN A 1 300 ? 75.007  119.637 131.825 1.00 73.32  ? 300 GLN A HE21 1 
ATOM 4416 H HE22 . GLN A 1 300 ? 74.689  118.478 132.703 1.00 74.84  ? 300 GLN A HE22 1 
ATOM 4417 N N    . ARG A 1 301 ? 82.021  119.114 131.028 1.00 70.92  ? 301 ARG A N    1 
ATOM 4418 C CA   . ARG A 1 301 ? 83.429  119.366 131.317 1.00 61.91  ? 301 ARG A CA   1 
ATOM 4419 C C    . ARG A 1 301 ? 84.040  120.295 130.275 1.00 60.61  ? 301 ARG A C    1 
ATOM 4420 O O    . ARG A 1 301 ? 84.734  121.261 130.615 1.00 64.47  ? 301 ARG A O    1 
ATOM 4421 C CB   . ARG A 1 301 ? 84.191  118.041 131.369 1.00 60.80  ? 301 ARG A CB   1 
ATOM 4422 C CG   . ARG A 1 301 ? 85.704  118.189 131.415 1.00 55.39  ? 301 ARG A CG   1 
ATOM 4423 C CD   . ARG A 1 301 ? 86.382  116.856 131.675 1.00 64.90  ? 301 ARG A CD   1 
ATOM 4424 N NE   . ARG A 1 301 ? 87.836  116.981 131.697 1.00 65.95  ? 301 ARG A NE   1 
ATOM 4425 C CZ   . ARG A 1 301 ? 88.657  116.518 130.762 1.00 59.13  ? 301 ARG A CZ   1 
ATOM 4426 N NH1  . ARG A 1 301 ? 88.206  115.896 129.683 1.00 58.19  ? 301 ARG A NH1  1 
ATOM 4427 N NH2  . ARG A 1 301 ? 89.967  116.687 130.910 1.00 52.70  ? 301 ARG A NH2  1 
ATOM 4428 H H    . ARG A 1 301 ? 81.826  118.287 130.893 1.00 67.86  ? 301 ARG A H    1 
ATOM 4429 H HA   . ARG A 1 301 ? 83.504  119.793 132.184 1.00 61.60  ? 301 ARG A HA   1 
ATOM 4430 H HB2  . ARG A 1 301 ? 83.918  117.557 132.165 1.00 62.58  ? 301 ARG A HB2  1 
ATOM 4431 H HB3  . ARG A 1 301 ? 83.970  117.524 130.580 1.00 64.88  ? 301 ARG A HB3  1 
ATOM 4432 H HG2  . ARG A 1 301 ? 86.022  118.526 130.563 1.00 55.99  ? 301 ARG A HG2  1 
ATOM 4433 H HG3  . ARG A 1 301 ? 85.946  118.799 132.130 1.00 58.00  ? 301 ARG A HG3  1 
ATOM 4434 H HD2  . ARG A 1 301 ? 86.100  116.527 132.543 1.00 64.95  ? 301 ARG A HD2  1 
ATOM 4435 H HD3  . ARG A 1 301 ? 86.120  116.226 130.987 1.00 63.71  ? 301 ARG A HD3  1 
ATOM 4436 H HE   . ARG A 1 301 ? 88.190  117.360 132.383 1.00 62.95  ? 301 ARG A HE   1 
ATOM 4437 H HH11 . ARG A 1 301 ? 87.364  115.777 129.566 1.00 60.76  ? 301 ARG A HH11 1 
ATOM 4438 H HH12 . ARG A 1 301 ? 88.762  115.609 129.094 1.00 58.39  ? 301 ARG A HH12 1 
ATOM 4439 H HH21 . ARG A 1 301 ? 90.272  117.089 131.607 1.00 55.72  ? 301 ARG A HH21 1 
ATOM 4440 H HH22 . ARG A 1 301 ? 90.509  116.393 130.312 1.00 54.56  ? 301 ARG A HH22 1 
ATOM 4441 N N    . VAL A 1 302 ? 83.787  120.018 128.996 1.00 59.98  ? 302 VAL A N    1 
ATOM 4442 C CA   . VAL A 1 302 ? 84.344  120.854 127.936 1.00 53.26  ? 302 VAL A CA   1 
ATOM 4443 C C    . VAL A 1 302 ? 83.760  122.260 128.007 1.00 54.04  ? 302 VAL A C    1 
ATOM 4444 O O    . VAL A 1 302 ? 84.473  123.252 127.812 1.00 59.74  ? 302 VAL A O    1 
ATOM 4445 C CB   . VAL A 1 302 ? 84.104  120.205 126.561 1.00 51.21  ? 302 VAL A CB   1 
ATOM 4446 C CG1  . VAL A 1 302 ? 84.266  121.233 125.449 1.00 53.32  ? 302 VAL A CG1  1 
ATOM 4447 C CG2  . VAL A 1 302 ? 85.058  119.041 126.352 1.00 56.90  ? 302 VAL A CG2  1 
ATOM 4448 H H    . VAL A 1 302 ? 83.305  119.362 128.719 1.00 61.60  ? 302 VAL A H    1 
ATOM 4449 H HA   . VAL A 1 302 ? 85.302  120.924 128.067 1.00 56.40  ? 302 VAL A HA   1 
ATOM 4450 H HB   . VAL A 1 302 ? 83.197  119.862 126.525 1.00 57.80  ? 302 VAL A HB   1 
ATOM 4451 H HG11 . VAL A 1 302 ? 84.281  120.773 124.596 1.00 55.36  ? 302 VAL A HG11 1 
ATOM 4452 H HG12 . VAL A 1 302 ? 83.523  121.854 125.473 1.00 56.80  ? 302 VAL A HG12 1 
ATOM 4453 H HG13 . VAL A 1 302 ? 85.100  121.710 125.581 1.00 54.35  ? 302 VAL A HG13 1 
ATOM 4454 H HG21 . VAL A 1 302 ? 84.898  118.655 125.477 1.00 58.20  ? 302 VAL A HG21 1 
ATOM 4455 H HG22 . VAL A 1 302 ? 85.970  119.367 126.408 1.00 55.96  ? 302 VAL A HG22 1 
ATOM 4456 H HG23 . VAL A 1 302 ? 84.901  118.377 127.041 1.00 61.26  ? 302 VAL A HG23 1 
ATOM 4457 N N    . ALA A 1 303 ? 82.457  122.371 128.278 1.00 56.88  ? 303 ALA A N    1 
ATOM 4458 C CA   . ALA A 1 303 ? 81.837  123.687 128.388 1.00 66.44  ? 303 ALA A CA   1 
ATOM 4459 C C    . ALA A 1 303 ? 82.463  124.494 129.517 1.00 71.55  ? 303 ALA A C    1 
ATOM 4460 O O    . ALA A 1 303 ? 82.733  125.691 129.362 1.00 72.79  ? 303 ALA A O    1 
ATOM 4461 C CB   . ALA A 1 303 ? 80.331  123.541 128.605 1.00 67.93  ? 303 ALA A CB   1 
ATOM 4462 H H    . ALA A 1 303 ? 81.921  121.710 128.399 1.00 60.28  ? 303 ALA A H    1 
ATOM 4463 H HA   . ALA A 1 303 ? 81.976  124.173 127.560 1.00 65.05  ? 303 ALA A HA   1 
ATOM 4464 H HB1  . ALA A 1 303 ? 79.935  124.424 128.676 1.00 66.87  ? 303 ALA A HB1  1 
ATOM 4465 H HB2  . ALA A 1 303 ? 79.948  123.066 127.852 1.00 64.99  ? 303 ALA A HB2  1 
ATOM 4466 H HB3  . ALA A 1 303 ? 80.177  123.044 129.424 1.00 65.81  ? 303 ALA A HB3  1 
ATOM 4467 N N    . ALA A 1 304 ? 82.703  123.855 130.664 1.00 72.98  ? 304 ALA A N    1 
ATOM 4468 C CA   . ALA A 1 304 ? 83.382  124.538 131.759 1.00 68.26  ? 304 ALA A CA   1 
ATOM 4469 C C    . ALA A 1 304 ? 84.793  124.943 131.354 1.00 62.92  ? 304 ALA A C    1 
ATOM 4470 O O    . ALA A 1 304 ? 85.261  126.033 131.703 1.00 65.55  ? 304 ALA A O    1 
ATOM 4471 C CB   . ALA A 1 304 ? 83.416  123.643 132.997 1.00 68.33  ? 304 ALA A CB   1 
ATOM 4472 H H    . ALA A 1 304 ? 82.485  123.040 130.830 1.00 68.37  ? 304 ALA A H    1 
ATOM 4473 H HA   . ALA A 1 304 ? 82.891  125.344 131.984 1.00 66.53  ? 304 ALA A HA   1 
ATOM 4474 H HB1  . ALA A 1 304 ? 83.945  124.078 133.683 1.00 66.51  ? 304 ALA A HB1  1 
ATOM 4475 H HB2  . ALA A 1 304 ? 82.510  123.503 133.313 1.00 66.45  ? 304 ALA A HB2  1 
ATOM 4476 H HB3  . ALA A 1 304 ? 83.821  122.794 132.759 1.00 65.98  ? 304 ALA A HB3  1 
ATOM 4477 N N    . ILE A 1 305 ? 85.486  124.074 130.617 1.00 59.95  ? 305 ILE A N    1 
ATOM 4478 C CA   . ILE A 1 305 ? 86.836  124.393 130.161 1.00 61.05  ? 305 ILE A CA   1 
ATOM 4479 C C    . ILE A 1 305 ? 86.814  125.605 129.238 1.00 62.28  ? 305 ILE A C    1 
ATOM 4480 O O    . ILE A 1 305 ? 87.671  126.492 129.331 1.00 63.83  ? 305 ILE A O    1 
ATOM 4481 C CB   . ILE A 1 305 ? 87.465  123.168 129.471 1.00 56.82  ? 305 ILE A CB   1 
ATOM 4482 C CG1  . ILE A 1 305 ? 88.008  122.193 130.519 1.00 63.56  ? 305 ILE A CG1  1 
ATOM 4483 C CG2  . ILE A 1 305 ? 88.562  123.593 128.499 1.00 50.05  ? 305 ILE A CG2  1 
ATOM 4484 C CD1  . ILE A 1 305 ? 89.407  122.518 130.999 1.00 65.08  ? 305 ILE A CD1  1 
ATOM 4485 H H    . ILE A 1 305 ? 85.200  123.302 130.369 1.00 62.04  ? 305 ILE A H    1 
ATOM 4486 H HA   . ILE A 1 305 ? 87.383  124.616 130.931 1.00 62.00  ? 305 ILE A HA   1 
ATOM 4487 H HB   . ILE A 1 305 ? 86.771  122.715 128.966 1.00 58.52  ? 305 ILE A HB   1 
ATOM 4488 H HG12 . ILE A 1 305 ? 87.420  122.205 131.290 1.00 63.46  ? 305 ILE A HG12 1 
ATOM 4489 H HG13 . ILE A 1 305 ? 88.027  121.303 130.134 1.00 61.53  ? 305 ILE A HG13 1 
ATOM 4490 H HG21 . ILE A 1 305 ? 89.099  122.817 128.276 1.00 52.66  ? 305 ILE A HG21 1 
ATOM 4491 H HG22 . ILE A 1 305 ? 88.155  123.949 127.693 1.00 53.36  ? 305 ILE A HG22 1 
ATOM 4492 H HG23 . ILE A 1 305 ? 89.118  124.268 128.918 1.00 56.38  ? 305 ILE A HG23 1 
ATOM 4493 H HD11 . ILE A 1 305 ? 89.580  122.028 131.817 1.00 61.68  ? 305 ILE A HD11 1 
ATOM 4494 H HD12 . ILE A 1 305 ? 90.047  122.257 130.317 1.00 64.74  ? 305 ILE A HD12 1 
ATOM 4495 H HD13 . ILE A 1 305 ? 89.470  123.472 131.166 1.00 63.39  ? 305 ILE A HD13 1 
ATOM 4496 N N    . ASN A 1 306 ? 85.835  125.663 128.335 1.00 70.10  ? 306 ASN A N    1 
ATOM 4497 C CA   . ASN A 1 306 ? 85.838  126.668 127.279 1.00 66.58  ? 306 ASN A CA   1 
ATOM 4498 C C    . ASN A 1 306 ? 85.482  128.063 127.777 1.00 60.82  ? 306 ASN A C    1 
ATOM 4499 O O    . ASN A 1 306 ? 85.608  129.022 127.009 1.00 54.28  ? 306 ASN A O    1 
ATOM 4500 C CB   . ASN A 1 306 ? 84.866  126.254 126.171 1.00 72.62  ? 306 ASN A CB   1 
ATOM 4501 C CG   . ASN A 1 306 ? 85.495  126.303 124.790 1.00 76.21  ? 306 ASN A CG   1 
ATOM 4502 O OD1  . ASN A 1 306 ? 86.698  126.522 124.648 1.00 71.09  ? 306 ASN A OD1  1 
ATOM 4503 N ND2  . ASN A 1 306 ? 84.681  126.092 123.763 1.00 74.37  ? 306 ASN A ND2  1 
ATOM 4504 H H    . ASN A 1 306 ? 85.157  125.134 128.316 1.00 66.46  ? 306 ASN A H    1 
ATOM 4505 H HA   . ASN A 1 306 ? 86.731  126.712 126.907 1.00 64.76  ? 306 ASN A HA   1 
ATOM 4506 H HB2  . ASN A 1 306 ? 84.567  125.345 126.332 1.00 68.55  ? 306 ASN A HB2  1 
ATOM 4507 H HB3  . ASN A 1 306 ? 84.107  126.859 126.175 1.00 68.84  ? 306 ASN A HB3  1 
ATOM 4508 H HD21 . ASN A 1 306 ? 83.845  125.941 123.900 1.00 72.89  ? 306 ASN A HD21 1 
ATOM 4509 H HD22 . ASN A 1 306 ? 84.988  126.109 122.960 1.00 73.59  ? 306 ASN A HD22 1 
ATOM 4510 N N    . GLY A 1 307 ? 85.047  128.203 129.026 1.00 68.03  ? 307 GLY A N    1 
ATOM 4511 C CA   . GLY A 1 307 ? 84.716  129.498 129.583 1.00 74.86  ? 307 GLY A CA   1 
ATOM 4512 C C    . GLY A 1 307 ? 83.244  129.842 129.610 1.00 80.62  ? 307 GLY A C    1 
ATOM 4513 O O    . GLY A 1 307 ? 82.901  130.976 129.966 1.00 75.53  ? 307 GLY A O    1 
ATOM 4514 H H    . GLY A 1 307 ? 84.934  127.551 129.574 1.00 67.29  ? 307 GLY A H    1 
ATOM 4515 H HA2  . GLY A 1 307 ? 85.046  129.538 130.494 1.00 72.50  ? 307 GLY A HA2  1 
ATOM 4516 H HA3  . GLY A 1 307 ? 85.171  130.186 129.073 1.00 70.06  ? 307 GLY A HA3  1 
ATOM 4517 N N    . LYS A 1 308 ? 82.365  128.910 129.248 1.00 88.58  ? 308 LYS A N    1 
ATOM 4518 C CA   . LYS A 1 308 ? 80.919  129.117 129.285 1.00 96.91  ? 308 LYS A CA   1 
ATOM 4519 C C    . LYS A 1 308 ? 80.333  128.114 130.274 1.00 95.67  ? 308 LYS A C    1 
ATOM 4520 O O    . LYS A 1 308 ? 80.118  126.946 129.934 1.00 92.25  ? 308 LYS A O    1 
ATOM 4521 C CB   . LYS A 1 308 ? 80.306  128.967 127.895 1.00 96.07  ? 308 LYS A CB   1 
ATOM 4522 C CG   . LYS A 1 308 ? 80.526  130.176 126.997 1.00 91.23  ? 308 LYS A CG   1 
ATOM 4523 C CD   . LYS A 1 308 ? 80.182  129.875 125.547 1.00 92.29  ? 308 LYS A CD   1 
ATOM 4524 C CE   . LYS A 1 308 ? 81.310  129.136 124.847 1.00 86.60  ? 308 LYS A CE   1 
ATOM 4525 N NZ   . LYS A 1 308 ? 81.072  129.014 123.383 1.00 87.11  ? 308 LYS A NZ   1 
ATOM 4526 H H    . LYS A 1 308 ? 82.589  128.128 128.970 1.00 81.46  ? 308 LYS A H    1 
ATOM 4527 H HA   . LYS A 1 308 ? 80.726  130.012 129.608 1.00 91.31  ? 308 LYS A HA   1 
ATOM 4528 H HB2  . LYS A 1 308 ? 80.704  128.197 127.460 1.00 87.64  ? 308 LYS A HB2  1 
ATOM 4529 H HB3  . LYS A 1 308 ? 79.350  128.836 127.987 1.00 93.95  ? 308 LYS A HB3  1 
ATOM 4530 H HG2  . LYS A 1 308 ? 79.959  130.903 127.297 1.00 90.07  ? 308 LYS A HG2  1 
ATOM 4531 H HG3  . LYS A 1 308 ? 81.458  130.440 127.039 1.00 87.43  ? 308 LYS A HG3  1 
ATOM 4532 H HD2  . LYS A 1 308 ? 79.388  129.318 125.516 1.00 91.05  ? 308 LYS A HD2  1 
ATOM 4533 H HD3  . LYS A 1 308 ? 80.025  130.708 125.076 1.00 91.75  ? 308 LYS A HD3  1 
ATOM 4534 H HE2  . LYS A 1 308 ? 82.139  129.623 124.978 1.00 84.29  ? 308 LYS A HE2  1 
ATOM 4535 H HE3  . LYS A 1 308 ? 81.385  128.243 125.218 1.00 84.15  ? 308 LYS A HE3  1 
ATOM 4536 H HZ1  . LYS A 1 308 ? 80.894  129.814 123.036 1.00 86.27  ? 308 LYS A HZ1  1 
ATOM 4537 H HZ2  . LYS A 1 308 ? 81.794  128.680 122.985 1.00 84.71  ? 308 LYS A HZ2  1 
ATOM 4538 H HZ3  . LYS A 1 308 ? 80.381  128.474 123.231 1.00 86.15  ? 308 LYS A HZ3  1 
ATOM 4539 N N    . ARG A 1 309 ? 80.077  128.575 131.498 1.00 96.96  ? 309 ARG A N    1 
ATOM 4540 C CA   . ARG A 1 309 ? 79.595  127.711 132.568 1.00 99.75  ? 309 ARG A CA   1 
ATOM 4541 C C    . ARG A 1 309 ? 78.074  127.627 132.606 1.00 102.80 ? 309 ARG A C    1 
ATOM 4542 O O    . ARG A 1 309 ? 77.517  126.535 132.767 1.00 108.85 ? 309 ARG A O    1 
ATOM 4543 C CB   . ARG A 1 309 ? 80.116  128.218 133.916 1.00 96.94  ? 309 ARG A CB   1 
ATOM 4544 C CG   . ARG A 1 309 ? 81.520  127.744 134.258 1.00 95.08  ? 309 ARG A CG   1 
ATOM 4545 C CD   . ARG A 1 309 ? 81.507  126.437 135.031 1.00 94.47  ? 309 ARG A CD   1 
ATOM 4546 N NE   . ARG A 1 309 ? 82.845  126.052 135.464 1.00 99.38  ? 309 ARG A NE   1 
ATOM 4547 C CZ   . ARG A 1 309 ? 83.131  124.934 136.117 1.00 99.36  ? 309 ARG A CZ   1 
ATOM 4548 N NH1  . ARG A 1 309 ? 82.191  124.057 136.432 1.00 104.08 ? 309 ARG A NH1  1 
ATOM 4549 N NH2  . ARG A 1 309 ? 84.392  124.687 136.460 1.00 89.80  ? 309 ARG A NH2  1 
ATOM 4550 H H    . ARG A 1 309 ? 80.176  129.397 131.733 1.00 95.14  ? 309 ARG A H    1 
ATOM 4551 H HA   . ARG A 1 309 ? 79.942  126.816 132.431 1.00 95.48  ? 309 ARG A HA   1 
ATOM 4552 H HB2  . ARG A 1 309 ? 80.127  129.187 133.901 1.00 97.61  ? 309 ARG A HB2  1 
ATOM 4553 H HB3  . ARG A 1 309 ? 79.521  127.907 134.616 1.00 96.86  ? 309 ARG A HB3  1 
ATOM 4554 H HG2  . ARG A 1 309 ? 82.018  127.605 133.437 1.00 91.04  ? 309 ARG A HG2  1 
ATOM 4555 H HG3  . ARG A 1 309 ? 81.959  128.415 134.805 1.00 97.36  ? 309 ARG A HG3  1 
ATOM 4556 H HD2  . ARG A 1 309 ? 80.951  126.538 135.819 1.00 95.54  ? 309 ARG A HD2  1 
ATOM 4557 H HD3  . ARG A 1 309 ? 81.158  125.733 134.462 1.00 91.81  ? 309 ARG A HD3  1 
ATOM 4558 H HE   . ARG A 1 309 ? 83.484  126.613 135.333 1.00 94.99  ? 309 ARG A HE   1 
ATOM 4559 H HH11 . ARG A 1 309 ? 81.372  124.204 136.216 1.00 99.90  ? 309 ARG A HH11 1 
ATOM 4560 H HH12 . ARG A 1 309 ? 82.400  123.338 136.855 1.00 101.25 ? 309 ARG A HH12 1 
ATOM 4561 H HH21 . ARG A 1 309 ? 85.010  125.251 136.260 1.00 88.35  ? 309 ARG A HH21 1 
ATOM 4562 H HH22 . ARG A 1 309 ? 84.589  123.965 136.883 1.00 91.15  ? 309 ARG A HH22 1 
ATOM 4563 N N    . ALA A 1 310 ? 77.391  128.765 132.460 1.00 101.81 ? 310 ALA A N    1 
ATOM 4564 C CA   . ALA A 1 310 ? 75.934  128.770 132.541 1.00 101.54 ? 310 ALA A CA   1 
ATOM 4565 C C    . ALA A 1 310 ? 75.316  127.928 131.433 1.00 104.04 ? 310 ALA A C    1 
ATOM 4566 O O    . ALA A 1 310 ? 74.345  127.198 131.665 1.00 104.24 ? 310 ALA A O    1 
ATOM 4567 C CB   . ALA A 1 310 ? 75.412  130.205 132.479 1.00 106.32 ? 310 ALA A CB   1 
ATOM 4568 H H    . ALA A 1 310 ? 77.744  129.536 132.316 1.00 101.33 ? 310 ALA A H    1 
ATOM 4569 H HA   . ALA A 1 310 ? 75.664  128.390 133.392 1.00 101.62 ? 310 ALA A HA   1 
ATOM 4570 H HB1  . ALA A 1 310 ? 75.688  130.605 131.640 1.00 106.23 ? 310 ALA A HB1  1 
ATOM 4571 H HB2  . ALA A 1 310 ? 74.443  130.191 132.536 1.00 105.89 ? 310 ALA A HB2  1 
ATOM 4572 H HB3  . ALA A 1 310 ? 75.780  130.707 133.223 1.00 105.95 ? 310 ALA A HB3  1 
ATOM 4573 N N    . VAL A 1 311 ? 75.861  128.018 130.218 1.00 103.44 ? 311 VAL A N    1 
ATOM 4574 C CA   . VAL A 1 311 ? 75.316  127.250 129.102 1.00 104.87 ? 311 VAL A CA   1 
ATOM 4575 C C    . VAL A 1 311 ? 75.398  125.758 129.401 1.00 103.40 ? 311 VAL A C    1 
ATOM 4576 O O    . VAL A 1 311 ? 74.428  125.014 129.213 1.00 104.39 ? 311 VAL A O    1 
ATOM 4577 C CB   . VAL A 1 311 ? 76.053  127.603 127.797 1.00 105.24 ? 311 VAL A CB   1 
ATOM 4578 C CG1  . VAL A 1 311 ? 75.451  126.840 126.623 1.00 100.79 ? 311 VAL A CG1  1 
ATOM 4579 C CG2  . VAL A 1 311 ? 76.006  129.105 127.545 1.00 99.71  ? 311 VAL A CG2  1 
ATOM 4580 H H    . VAL A 1 311 ? 76.539  128.508 130.020 1.00 102.31 ? 311 VAL A H    1 
ATOM 4581 H HA   . VAL A 1 311 ? 74.381  127.481 128.988 1.00 104.31 ? 311 VAL A HA   1 
ATOM 4582 H HB   . VAL A 1 311 ? 76.983  127.342 127.879 1.00 103.02 ? 311 VAL A HB   1 
ATOM 4583 H HG11 . VAL A 1 311 ? 74.613  126.438 126.901 1.00 100.35 ? 311 VAL A HG11 1 
ATOM 4584 H HG12 . VAL A 1 311 ? 75.294  127.458 125.892 1.00 98.65  ? 311 VAL A HG12 1 
ATOM 4585 H HG13 . VAL A 1 311 ? 76.074  126.151 126.344 1.00 97.49  ? 311 VAL A HG13 1 
ATOM 4586 H HG21 . VAL A 1 311 ? 76.389  129.291 126.674 1.00 99.53  ? 311 VAL A HG21 1 
ATOM 4587 H HG22 . VAL A 1 311 ? 75.083  129.400 127.570 1.00 101.32 ? 311 VAL A HG22 1 
ATOM 4588 H HG23 . VAL A 1 311 ? 76.517  129.559 128.233 1.00 99.48  ? 311 VAL A HG23 1 
ATOM 4589 N N    . GLY A 1 312 ? 76.558  125.300 129.872 1.00 99.38  ? 312 GLY A N    1 
ATOM 4590 C CA   . GLY A 1 312 ? 76.700  123.894 130.211 1.00 95.61  ? 312 GLY A CA   1 
ATOM 4591 C C    . GLY A 1 312 ? 75.802  123.479 131.361 1.00 100.56 ? 312 GLY A C    1 
ATOM 4592 O O    . GLY A 1 312 ? 75.276  122.364 131.379 1.00 100.92 ? 312 GLY A O    1 
ATOM 4593 H H    . GLY A 1 312 ? 77.263  125.776 130.001 1.00 99.79  ? 312 GLY A H    1 
ATOM 4594 H HA2  . GLY A 1 312 ? 76.479  123.351 129.438 1.00 97.05  ? 312 GLY A HA2  1 
ATOM 4595 H HA3  . GLY A 1 312 ? 77.620  123.714 130.461 1.00 92.01  ? 312 GLY A HA3  1 
ATOM 4596 N N    . ASP A 1 313 ? 75.616  124.370 132.338 1.00 106.29 ? 313 ASP A N    1 
ATOM 4597 C CA   . ASP A 1 313 ? 74.781  124.039 133.487 1.00 107.17 ? 313 ASP A CA   1 
ATOM 4598 C C    . ASP A 1 313 ? 73.334  123.804 133.071 1.00 110.04 ? 313 ASP A C    1 
ATOM 4599 O O    . ASP A 1 313 ? 72.679  122.880 133.569 1.00 110.88 ? 313 ASP A O    1 
ATOM 4600 C CB   . ASP A 1 313 ? 74.861  125.155 134.530 1.00 103.93 ? 313 ASP A CB   1 
ATOM 4601 C CG   . ASP A 1 313 ? 76.021  124.975 135.494 1.00 103.25 ? 313 ASP A CG   1 
ATOM 4602 O OD1  . ASP A 1 313 ? 76.519  123.838 135.632 1.00 100.39 ? 313 ASP A OD1  1 
ATOM 4603 O OD2  . ASP A 1 313 ? 76.436  125.976 136.115 1.00 108.73 ? 313 ASP A OD2  1 
ATOM 4604 H H    . ASP A 1 313 ? 75.958  125.159 132.357 1.00 105.37 ? 313 ASP A H    1 
ATOM 4605 H HA   . ASP A 1 313 ? 75.107  123.219 133.889 1.00 104.06 ? 313 ASP A HA   1 
ATOM 4606 H HB2  . ASP A 1 313 ? 74.977  126.005 134.076 1.00 105.01 ? 313 ASP A HB2  1 
ATOM 4607 H HB3  . ASP A 1 313 ? 74.041  125.165 135.047 1.00 103.55 ? 313 ASP A HB3  1 
ATOM 4608 N N    . THR A 1 314 ? 72.816  124.629 132.159 1.00 112.76 ? 314 THR A N    1 
ATOM 4609 C CA   . THR A 1 314 ? 71.424  124.516 131.740 1.00 113.06 ? 314 THR A CA   1 
ATOM 4610 C C    . THR A 1 314 ? 71.134  123.231 130.975 1.00 110.70 ? 314 THR A C    1 
ATOM 4611 O O    . THR A 1 314 ? 69.960  122.883 130.810 1.00 105.49 ? 314 THR A O    1 
ATOM 4612 C CB   . THR A 1 314 ? 71.037  125.717 130.874 1.00 112.37 ? 314 THR A CB   1 
ATOM 4613 O OG1  . THR A 1 314 ? 72.003  125.889 129.829 1.00 111.97 ? 314 THR A OG1  1 
ATOM 4614 C CG2  . THR A 1 314 ? 70.972  126.984 131.715 1.00 111.79 ? 314 THR A CG2  1 
ATOM 4615 H H    . THR A 1 314 ? 73.251  125.260 131.770 1.00 109.13 ? 314 THR A H    1 
ATOM 4616 H HA   . THR A 1 314 ? 70.859  124.525 132.529 1.00 111.18 ? 314 THR A HA   1 
ATOM 4617 H HB   . THR A 1 314 ? 70.163  125.564 130.483 1.00 111.17 ? 314 THR A HB   1 
ATOM 4618 H HG1  . THR A 1 314 ? 72.024  125.204 129.342 1.00 109.13 ? 314 THR A HG1  1 
ATOM 4619 H HG21 . THR A 1 314 ? 70.740  127.741 131.156 1.00 111.11 ? 314 THR A HG21 1 
ATOM 4620 H HG22 . THR A 1 314 ? 70.301  126.887 132.409 1.00 111.56 ? 314 THR A HG22 1 
ATOM 4621 H HG23 . THR A 1 314 ? 71.833  127.151 132.130 1.00 110.08 ? 314 THR A HG23 1 
ATOM 4622 N N    . LEU A 1 315 ? 72.160  122.524 130.509 1.00 109.42 ? 315 LEU A N    1 
ATOM 4623 C CA   . LEU A 1 315 ? 71.940  121.306 129.743 1.00 110.58 ? 315 LEU A CA   1 
ATOM 4624 C C    . LEU A 1 315 ? 71.285  120.235 130.607 1.00 113.74 ? 315 LEU A C    1 
ATOM 4625 O O    . LEU A 1 315 ? 71.587  120.100 131.797 1.00 115.40 ? 315 LEU A O    1 
ATOM 4626 C CB   . LEU A 1 315 ? 73.262  120.784 129.183 1.00 103.31 ? 315 LEU A CB   1 
ATOM 4627 C CG   . LEU A 1 315 ? 73.175  120.140 127.799 1.00 101.71 ? 315 LEU A CG   1 
ATOM 4628 C CD1  . LEU A 1 315 ? 73.037  121.200 126.716 1.00 99.57  ? 315 LEU A CD1  1 
ATOM 4629 C CD2  . LEU A 1 315 ? 74.385  119.261 127.545 1.00 95.52  ? 315 LEU A CD2  1 
ATOM 4630 H H    . LEU A 1 315 ? 72.987  122.729 130.622 1.00 107.20 ? 315 LEU A H    1 
ATOM 4631 H HA   . LEU A 1 315 ? 71.349  121.498 128.999 1.00 109.27 ? 315 LEU A HA   1 
ATOM 4632 H HB2  . LEU A 1 315 ? 73.884  121.526 129.121 1.00 102.64 ? 315 LEU A HB2  1 
ATOM 4633 H HB3  . LEU A 1 315 ? 73.613  120.117 129.794 1.00 100.99 ? 315 LEU A HB3  1 
ATOM 4634 H HG   . LEU A 1 315 ? 72.386  119.577 127.765 1.00 103.66 ? 315 LEU A HG   1 
ATOM 4635 H HD11 . LEU A 1 315 ? 73.018  120.764 125.849 1.00 98.55  ? 315 LEU A HD11 1 
ATOM 4636 H HD12 . LEU A 1 315 ? 72.212  121.690 126.857 1.00 101.66 ? 315 LEU A HD12 1 
ATOM 4637 H HD13 . LEU A 1 315 ? 73.794  121.804 126.767 1.00 99.32  ? 315 LEU A HD13 1 
ATOM 4638 H HD21 . LEU A 1 315 ? 74.296  118.848 126.671 1.00 92.77  ? 315 LEU A HD21 1 
ATOM 4639 H HD22 . LEU A 1 315 ? 75.185  119.809 127.573 1.00 93.90  ? 315 LEU A HD22 1 
ATOM 4640 H HD23 . LEU A 1 315 ? 74.428  118.577 128.231 1.00 91.00  ? 315 LEU A HD23 1 
ATOM 4641 N N    . THR A 1 316 ? 70.386  119.473 130.000 1.00 110.05 ? 316 THR A N    1 
ATOM 4642 C CA   . THR A 1 316 ? 69.703  118.367 130.649 1.00 107.44 ? 316 THR A CA   1 
ATOM 4643 C C    . THR A 1 316 ? 69.633  117.201 129.676 1.00 109.59 ? 316 THR A C    1 
ATOM 4644 O O    . THR A 1 316 ? 69.722  117.396 128.459 1.00 112.59 ? 316 THR A O    1 
ATOM 4645 C CB   . THR A 1 316 ? 68.287  118.750 131.102 1.00 106.35 ? 316 THR A CB   1 
ATOM 4646 O OG1  . THR A 1 316 ? 67.389  118.682 129.987 1.00 103.37 ? 316 THR A OG1  1 
ATOM 4647 C CG2  . THR A 1 316 ? 68.267  120.157 131.686 1.00 106.87 ? 316 THR A CG2  1 
ATOM 4648 H H    . THR A 1 316 ? 70.146  119.584 129.182 1.00 108.84 ? 316 THR A H    1 
ATOM 4649 H HA   . THR A 1 316 ? 70.212  118.094 131.428 1.00 107.70 ? 316 THR A HA   1 
ATOM 4650 H HB   . THR A 1 316 ? 67.992  118.133 131.790 1.00 107.00 ? 316 THR A HB   1 
ATOM 4651 H HG1  . THR A 1 316 ? 66.612  118.887 130.232 1.00 103.29 ? 316 THR A HG1  1 
ATOM 4652 H HG21 . THR A 1 316 ? 68.973  120.252 132.344 1.00 108.53 ? 316 THR A HG21 1 
ATOM 4653 H HG22 . THR A 1 316 ? 68.400  120.811 130.982 1.00 108.43 ? 316 THR A HG22 1 
ATOM 4654 H HG23 . THR A 1 316 ? 67.413  120.325 132.113 1.00 106.08 ? 316 THR A HG23 1 
ATOM 4655 N N    . PRO A 1 317 ? 69.475  115.975 130.181 1.00 107.72 ? 317 PRO A N    1 
ATOM 4656 C CA   . PRO A 1 317 ? 69.417  114.816 129.273 1.00 102.63 ? 317 PRO A CA   1 
ATOM 4657 C C    . PRO A 1 317 ? 68.254  114.866 128.298 1.00 103.91 ? 317 PRO A C    1 
ATOM 4658 O O    . PRO A 1 317 ? 68.342  114.262 127.222 1.00 104.02 ? 317 PRO A O    1 
ATOM 4659 C CB   . PRO A 1 317 ? 69.299  113.611 130.220 1.00 102.70 ? 317 PRO A CB   1 
ATOM 4660 C CG   . PRO A 1 317 ? 69.430  114.134 131.608 1.00 103.42 ? 317 PRO A CG   1 
ATOM 4661 C CD   . PRO A 1 317 ? 69.245  115.610 131.588 1.00 107.02 ? 317 PRO A CD   1 
ATOM 4662 H HA   . PRO A 1 317 ? 70.246  114.743 128.775 1.00 102.41 ? 317 PRO A HA   1 
ATOM 4663 H HB2  . PRO A 1 317 ? 68.434  113.191 130.098 1.00 103.75 ? 317 PRO A HB2  1 
ATOM 4664 H HB3  . PRO A 1 317 ? 70.011  112.981 130.028 1.00 103.06 ? 317 PRO A HB3  1 
ATOM 4665 H HG2  . PRO A 1 317 ? 68.751  113.723 132.165 1.00 103.62 ? 317 PRO A HG2  1 
ATOM 4666 H HG3  . PRO A 1 317 ? 70.313  113.916 131.945 1.00 102.44 ? 317 PRO A HG3  1 
ATOM 4667 H HD2  . PRO A 1 317 ? 68.342  115.842 131.855 1.00 106.99 ? 317 PRO A HD2  1 
ATOM 4668 H HD3  . PRO A 1 317 ? 69.904  116.032 132.161 1.00 106.30 ? 317 PRO A HD3  1 
ATOM 4669 N N    . GLN A 1 318 ? 67.171  115.571 128.630 1.00 107.32 ? 318 GLN A N    1 
ATOM 4670 C CA   . GLN A 1 318 ? 66.014  115.608 127.740 1.00 103.51 ? 318 GLN A CA   1 
ATOM 4671 C C    . GLN A 1 318 ? 66.337  116.378 126.466 1.00 104.20 ? 318 GLN A C    1 
ATOM 4672 O O    . GLN A 1 318 ? 66.050  115.914 125.355 1.00 104.36 ? 318 GLN A O    1 
ATOM 4673 C CB   . GLN A 1 318 ? 64.797  116.223 128.445 1.00 104.35 ? 318 GLN A CB   1 
ATOM 4674 C CG   . GLN A 1 318 ? 64.364  115.585 129.781 1.00 106.27 ? 318 GLN A CG   1 
ATOM 4675 C CD   . GLN A 1 318 ? 65.423  115.625 130.868 1.00 112.06 ? 318 GLN A CD   1 
ATOM 4676 O OE1  . GLN A 1 318 ? 66.196  114.681 131.033 1.00 108.14 ? 318 GLN A OE1  1 
ATOM 4677 N NE2  . GLN A 1 318 ? 65.466  116.724 131.612 1.00 112.74 ? 318 GLN A NE2  1 
ATOM 4678 H H    . GLN A 1 318 ? 67.102  116.051 129.336 1.00 107.61 ? 318 GLN A H    1 
ATOM 4679 H HA   . GLN A 1 318 ? 65.784  114.700 127.488 1.00 104.51 ? 318 GLN A HA   1 
ATOM 4680 H HB2  . GLN A 1 318 ? 64.992  117.156 128.624 1.00 106.00 ? 318 GLN A HB2  1 
ATOM 4681 H HB3  . GLN A 1 318 ? 64.039  116.165 127.843 1.00 103.98 ? 318 GLN A HB3  1 
ATOM 4682 H HG2  . GLN A 1 318 ? 63.584  116.058 130.112 1.00 105.97 ? 318 GLN A HG2  1 
ATOM 4683 H HG3  . GLN A 1 318 ? 64.140  114.655 129.623 1.00 105.90 ? 318 GLN A HG3  1 
ATOM 4684 H HE21 . GLN A 1 318 ? 64.910  117.364 131.467 1.00 110.39 ? 318 GLN A HE21 1 
ATOM 4685 H HE22 . GLN A 1 318 ? 66.049  116.795 132.241 1.00 109.56 ? 318 GLN A HE22 1 
ATOM 4686 N N    . VAL A 1 319 ? 66.936  117.562 126.607 1.00 105.89 ? 319 VAL A N    1 
ATOM 4687 C CA   . VAL A 1 319 ? 67.351  118.327 125.435 1.00 108.00 ? 319 VAL A CA   1 
ATOM 4688 C C    . VAL A 1 319 ? 68.410  117.560 124.657 1.00 108.33 ? 319 VAL A C    1 
ATOM 4689 O O    . VAL A 1 319 ? 68.443  117.597 123.421 1.00 111.93 ? 319 VAL A O    1 
ATOM 4690 C CB   . VAL A 1 319 ? 67.855  119.720 125.856 1.00 110.10 ? 319 VAL A CB   1 
ATOM 4691 C CG1  . VAL A 1 319 ? 68.597  120.388 124.704 1.00 111.21 ? 319 VAL A CG1  1 
ATOM 4692 C CG2  . VAL A 1 319 ? 66.693  120.582 126.332 1.00 114.28 ? 319 VAL A CG2  1 
ATOM 4693 H H    . VAL A 1 319 ? 67.111  117.939 127.360 1.00 106.93 ? 319 VAL A H    1 
ATOM 4694 H HA   . VAL A 1 319 ? 66.584  118.450 124.853 1.00 108.59 ? 319 VAL A HA   1 
ATOM 4695 H HB   . VAL A 1 319 ? 68.476  119.620 126.594 1.00 108.28 ? 319 VAL A HB   1 
ATOM 4696 H HG11 . VAL A 1 319 ? 68.181  120.132 123.866 1.00 111.05 ? 319 VAL A HG11 1 
ATOM 4697 H HG12 . VAL A 1 319 ? 68.553  121.350 124.814 1.00 111.35 ? 319 VAL A HG12 1 
ATOM 4698 H HG13 . VAL A 1 319 ? 69.524  120.100 124.718 1.00 109.30 ? 319 VAL A HG13 1 
ATOM 4699 H HG21 . VAL A 1 319 ? 65.905  120.025 126.428 1.00 110.57 ? 319 VAL A HG21 1 
ATOM 4700 H HG22 . VAL A 1 319 ? 66.924  120.977 127.187 1.00 111.79 ? 319 VAL A HG22 1 
ATOM 4701 H HG23 . VAL A 1 319 ? 66.525  121.281 125.680 1.00 114.04 ? 319 VAL A HG23 1 
ATOM 4702 N N    . LEU A 1 320 ? 69.298  116.861 125.366 1.00 100.02 ? 320 LEU A N    1 
ATOM 4703 C CA   . LEU A 1 320 ? 70.323  116.071 124.692 1.00 98.58  ? 320 LEU A CA   1 
ATOM 4704 C C    . LEU A 1 320 ? 69.698  114.990 123.820 1.00 103.50 ? 320 LEU A C    1 
ATOM 4705 O O    . LEU A 1 320 ? 70.117  114.785 122.674 1.00 104.51 ? 320 LEU A O    1 
ATOM 4706 C CB   . LEU A 1 320 ? 71.262  115.450 125.728 1.00 96.43  ? 320 LEU A CB   1 
ATOM 4707 C CG   . LEU A 1 320 ? 72.661  115.004 125.287 1.00 96.41  ? 320 LEU A CG   1 
ATOM 4708 C CD1  . LEU A 1 320 ? 73.285  115.966 124.290 1.00 96.32  ? 320 LEU A CD1  1 
ATOM 4709 C CD2  . LEU A 1 320 ? 73.563  114.841 126.501 1.00 92.96  ? 320 LEU A CD2  1 
ATOM 4710 H H    . LEU A 1 320 ? 69.327  116.827 126.225 1.00 102.91 ? 320 LEU A H    1 
ATOM 4711 H HA   . LEU A 1 320 ? 70.832  116.662 124.117 1.00 100.73 ? 320 LEU A HA   1 
ATOM 4712 H HB2  . LEU A 1 320 ? 71.388  116.099 126.438 1.00 99.42  ? 320 LEU A HB2  1 
ATOM 4713 H HB3  . LEU A 1 320 ? 70.822  114.666 126.092 1.00 99.54  ? 320 LEU A HB3  1 
ATOM 4714 H HG   . LEU A 1 320 ? 72.588  114.139 124.854 1.00 95.58  ? 320 LEU A HG   1 
ATOM 4715 H HD11 . LEU A 1 320 ? 72.843  115.857 123.435 1.00 96.20  ? 320 LEU A HD11 1 
ATOM 4716 H HD12 . LEU A 1 320 ? 73.168  116.874 124.611 1.00 96.71  ? 320 LEU A HD12 1 
ATOM 4717 H HD13 . LEU A 1 320 ? 74.229  115.762 124.203 1.00 94.11  ? 320 LEU A HD13 1 
ATOM 4718 H HD21 . LEU A 1 320 ? 74.437  114.542 126.207 1.00 87.52  ? 320 LEU A HD21 1 
ATOM 4719 H HD22 . LEU A 1 320 ? 73.640  115.697 126.952 1.00 91.39  ? 320 LEU A HD22 1 
ATOM 4720 H HD23 . LEU A 1 320 ? 73.171  114.186 127.099 1.00 90.04  ? 320 LEU A HD23 1 
ATOM 4721 N N    . LEU A 1 321 ? 68.692  114.287 124.344 1.00 106.06 ? 321 LEU A N    1 
ATOM 4722 C CA   . LEU A 1 321 ? 68.015  113.267 123.551 1.00 100.97 ? 321 LEU A CA   1 
ATOM 4723 C C    . LEU A 1 321 ? 67.253  113.888 122.386 1.00 106.68 ? 321 LEU A C    1 
ATOM 4724 O O    . LEU A 1 321 ? 67.284  113.364 121.267 1.00 106.44 ? 321 LEU A O    1 
ATOM 4725 C CB   . LEU A 1 321 ? 67.070  112.457 124.438 1.00 93.97  ? 321 LEU A CB   1 
ATOM 4726 H H    . LEU A 1 321 ? 68.389  114.381 125.144 1.00 104.27 ? 321 LEU A H    1 
ATOM 4727 H HA   . LEU A 1 321 ? 68.677  112.659 123.186 1.00 100.90 ? 321 LEU A HA   1 
ATOM 4728 N N    . SER A 1 322 ? 66.565  115.006 122.630 1.00 109.84 ? 322 SER A N    1 
ATOM 4729 C CA   . SER A 1 322 ? 65.774  115.631 121.573 1.00 106.45 ? 322 SER A CA   1 
ATOM 4730 C C    . SER A 1 322 ? 66.656  116.111 120.426 1.00 105.50 ? 322 SER A C    1 
ATOM 4731 O O    . SER A 1 322 ? 66.311  115.935 119.252 1.00 108.32 ? 322 SER A O    1 
ATOM 4732 C CB   . SER A 1 322 ? 64.965  116.795 122.145 1.00 103.12 ? 322 SER A CB   1 
ATOM 4733 O OG   . SER A 1 322 ? 65.711  117.999 122.112 1.00 102.93 ? 322 SER A OG   1 
ATOM 4734 H H    . SER A 1 322 ? 66.540  115.415 123.386 1.00 106.82 ? 322 SER A H    1 
ATOM 4735 H HA   . SER A 1 322 ? 65.150  114.979 121.219 1.00 106.03 ? 322 SER A HA   1 
ATOM 4736 H HB2  . SER A 1 322 ? 64.161  116.909 121.614 1.00 103.35 ? 322 SER A HB2  1 
ATOM 4737 H HB3  . SER A 1 322 ? 64.730  116.594 123.065 1.00 104.69 ? 322 SER A HB3  1 
ATOM 4738 H HG   . SER A 1 322 ? 66.420  117.910 122.554 1.00 105.61 ? 322 SER A HG   1 
ATOM 4739 N N    . ALA A 1 323 ? 67.800  116.719 120.747 1.00 103.94 ? 323 ALA A N    1 
ATOM 4740 C CA   . ALA A 1 323 ? 68.632  117.325 119.713 1.00 106.70 ? 323 ALA A CA   1 
ATOM 4741 C C    . ALA A 1 323 ? 69.296  116.280 118.827 1.00 109.22 ? 323 ALA A C    1 
ATOM 4742 O O    . ALA A 1 323 ? 69.630  116.575 117.673 1.00 106.29 ? 323 ALA A O    1 
ATOM 4743 C CB   . ALA A 1 323 ? 69.695  118.217 120.354 1.00 102.18 ? 323 ALA A CB   1 
ATOM 4744 H H    . ALA A 1 323 ? 68.111  116.793 121.545 1.00 105.28 ? 323 ALA A H    1 
ATOM 4745 H HA   . ALA A 1 323 ? 68.075  117.883 119.149 1.00 106.47 ? 323 ALA A HA   1 
ATOM 4746 H HB1  . ALA A 1 323 ? 70.242  118.608 119.655 1.00 102.23 ? 323 ALA A HB1  1 
ATOM 4747 H HB2  . ALA A 1 323 ? 69.255  118.916 120.863 1.00 102.94 ? 323 ALA A HB2  1 
ATOM 4748 H HB3  . ALA A 1 323 ? 70.247  117.677 120.941 1.00 102.08 ? 323 ALA A HB3  1 
ATOM 4749 N N    . MET A 1 324 ? 69.495  115.065 119.334 1.00 111.30 ? 324 MET A N    1 
ATOM 4750 C CA   . MET A 1 324 ? 70.221  114.035 118.607 1.00 113.27 ? 324 MET A CA   1 
ATOM 4751 C C    . MET A 1 324 ? 69.274  113.042 117.937 1.00 120.39 ? 324 MET A C    1 
ATOM 4752 O O    . MET A 1 324 ? 69.727  112.027 117.399 1.00 121.02 ? 324 MET A O    1 
ATOM 4753 C CB   . MET A 1 324 ? 71.184  113.318 119.564 1.00 106.73 ? 324 MET A CB   1 
ATOM 4754 C CG   . MET A 1 324 ? 72.025  112.204 118.953 1.00 105.26 ? 324 MET A CG   1 
ATOM 4755 S SD   . MET A 1 324 ? 72.942  112.798 117.515 1.00 104.73 ? 324 MET A SD   1 
ATOM 4756 C CE   . MET A 1 324 ? 74.616  112.855 118.150 1.00 96.38  ? 324 MET A CE   1 
ATOM 4757 H H    . MET A 1 324 ? 69.210  114.809 120.104 1.00 108.76 ? 324 MET A H    1 
ATOM 4758 H HA   . MET A 1 324 ? 70.755  114.460 117.919 1.00 109.68 ? 324 MET A HA   1 
ATOM 4759 H HB2  . MET A 1 324 ? 71.794  113.973 119.934 1.00 106.66 ? 324 MET A HB2  1 
ATOM 4760 H HB3  . MET A 1 324 ? 70.661  112.922 120.278 1.00 107.81 ? 324 MET A HB3  1 
ATOM 4761 H HG2  . MET A 1 324 ? 72.670  111.900 119.612 1.00 104.58 ? 324 MET A HG2  1 
ATOM 4762 H HG3  . MET A 1 324 ? 71.464  111.463 118.684 1.00 103.14 ? 324 MET A HG3  1 
ATOM 4763 H HE1  . MET A 1 324 ? 75.208  113.164 117.445 1.00 88.68  ? 324 MET A HE1  1 
ATOM 4764 H HE2  . MET A 1 324 ? 74.648  113.469 118.901 1.00 98.48  ? 324 MET A HE2  1 
ATOM 4765 H HE3  . MET A 1 324 ? 74.878  111.965 118.437 1.00 97.43  ? 324 MET A HE3  1 
ATOM 4766 N N    . GLN A 1 325 ? 67.968  113.332 117.932 1.00 121.83 ? 325 GLN A N    1 
ATOM 4767 C CA   . GLN A 1 325 ? 67.000  112.414 117.339 1.00 120.05 ? 325 GLN A CA   1 
ATOM 4768 C C    . GLN A 1 325 ? 67.259  112.196 115.854 1.00 123.37 ? 325 GLN A C    1 
ATOM 4769 O O    . GLN A 1 325 ? 66.939  111.128 115.321 1.00 124.10 ? 325 GLN A O    1 
ATOM 4770 C CB   . GLN A 1 325 ? 65.581  112.947 117.546 1.00 115.97 ? 325 GLN A CB   1 
ATOM 4771 C CG   . GLN A 1 325 ? 65.076  112.862 118.977 1.00 112.78 ? 325 GLN A CG   1 
ATOM 4772 C CD   . GLN A 1 325 ? 63.577  113.075 119.075 1.00 116.18 ? 325 GLN A CD   1 
ATOM 4773 O OE1  . GLN A 1 325 ? 62.888  113.189 118.060 1.00 122.29 ? 325 GLN A OE1  1 
ATOM 4774 N NE2  . GLN A 1 325 ? 63.062  113.128 120.298 1.00 117.69 ? 325 GLN A NE2  1 
ATOM 4775 H H    . GLN A 1 325 ? 67.620  114.046 118.262 1.00 116.17 ? 325 GLN A H    1 
ATOM 4776 H HA   . GLN A 1 325 ? 67.065  111.555 117.784 1.00 118.54 ? 325 GLN A HA   1 
ATOM 4777 H HB2  . GLN A 1 325 ? 65.561  113.880 117.286 1.00 115.75 ? 325 GLN A HB2  1 
ATOM 4778 H HB3  . GLN A 1 325 ? 64.973  112.438 116.987 1.00 117.40 ? 325 GLN A HB3  1 
ATOM 4779 H HG2  . GLN A 1 325 ? 65.277  111.982 119.332 1.00 113.06 ? 325 GLN A HG2  1 
ATOM 4780 H HG3  . GLN A 1 325 ? 65.515  113.543 119.510 1.00 113.12 ? 325 GLN A HG3  1 
ATOM 4781 H HE21 . GLN A 1 325 ? 63.574  113.043 120.984 1.00 115.13 ? 325 GLN A HE21 1 
ATOM 4782 H HE22 . GLN A 1 325 ? 62.217  113.246 120.404 1.00 117.58 ? 325 GLN A HE22 1 
ATOM 4783 N N    . GLU A 1 326 ? 67.830  113.190 115.170 1.00 123.87 ? 326 GLU A N    1 
ATOM 4784 C CA   . GLU A 1 326 ? 68.054  113.059 113.734 1.00 123.45 ? 326 GLU A CA   1 
ATOM 4785 C C    . GLU A 1 326 ? 68.981  111.889 113.425 1.00 120.67 ? 326 GLU A C    1 
ATOM 4786 O O    . GLU A 1 326 ? 68.713  111.098 112.513 1.00 121.05 ? 326 GLU A O    1 
ATOM 4787 C CB   . GLU A 1 326 ? 68.632  114.358 113.174 1.00 122.21 ? 326 GLU A CB   1 
ATOM 4788 C CG   . GLU A 1 326 ? 67.590  115.417 112.852 1.00 124.59 ? 326 GLU A CG   1 
ATOM 4789 C CD   . GLU A 1 326 ? 66.845  115.895 114.082 1.00 120.73 ? 326 GLU A CD   1 
ATOM 4790 O OE1  . GLU A 1 326 ? 67.447  116.626 114.898 1.00 111.74 ? 326 GLU A OE1  1 
ATOM 4791 O OE2  . GLU A 1 326 ? 65.657  115.541 114.235 1.00 120.82 ? 326 GLU A OE2  1 
ATOM 4792 H H    . GLU A 1 326 ? 68.092  113.936 115.509 1.00 120.76 ? 326 GLU A H    1 
ATOM 4793 H HA   . GLU A 1 326 ? 67.205  112.894 113.294 1.00 122.65 ? 326 GLU A HA   1 
ATOM 4794 H HB2  . GLU A 1 326 ? 69.245  114.732 113.826 1.00 119.40 ? 326 GLU A HB2  1 
ATOM 4795 H HB3  . GLU A 1 326 ? 69.109  114.156 112.354 1.00 121.68 ? 326 GLU A HB3  1 
ATOM 4796 H HG2  . GLU A 1 326 ? 68.033  116.182 112.453 1.00 121.33 ? 326 GLU A HG2  1 
ATOM 4797 H HG3  . GLU A 1 326 ? 66.943  115.048 112.232 1.00 123.73 ? 326 GLU A HG3  1 
ATOM 4798 N N    . GLU A 1 327 ? 70.077  111.762 114.176 1.00 116.84 ? 327 GLU A N    1 
ATOM 4799 C CA   . GLU A 1 327 ? 71.003  110.657 113.948 1.00 117.76 ? 327 GLU A CA   1 
ATOM 4800 C C    . GLU A 1 327 ? 70.388  109.328 114.366 1.00 126.68 ? 327 GLU A C    1 
ATOM 4801 O O    . GLU A 1 327 ? 70.521  108.324 113.656 1.00 131.04 ? 327 GLU A O    1 
ATOM 4802 C CB   . GLU A 1 327 ? 72.300  110.901 114.716 1.00 107.64 ? 327 GLU A CB   1 
ATOM 4803 C CG   . GLU A 1 327 ? 73.319  111.761 113.987 1.00 107.12 ? 327 GLU A CG   1 
ATOM 4804 C CD   . GLU A 1 327 ? 74.718  111.179 114.047 1.00 101.13 ? 327 GLU A CD   1 
ATOM 4805 O OE1  . GLU A 1 327 ? 75.386  111.341 115.089 1.00 100.54 ? 327 GLU A OE1  1 
ATOM 4806 O OE2  . GLU A 1 327 ? 75.150  110.558 113.053 1.00 92.30  ? 327 GLU A OE2  1 
ATOM 4807 H H    . GLU A 1 327 ? 70.304  112.295 114.811 1.00 117.29 ? 327 GLU A H    1 
ATOM 4808 H HA   . GLU A 1 327 ? 71.216  110.611 113.003 1.00 117.44 ? 327 GLU A HA   1 
ATOM 4809 H HB2  . GLU A 1 327 ? 72.074  111.337 115.548 1.00 109.42 ? 327 GLU A HB2  1 
ATOM 4810 H HB3  . GLU A 1 327 ? 72.721  110.047 114.900 1.00 106.97 ? 327 GLU A HB3  1 
ATOM 4811 H HG2  . GLU A 1 327 ? 73.065  111.838 113.055 1.00 108.48 ? 327 GLU A HG2  1 
ATOM 4812 H HG3  . GLU A 1 327 ? 73.343  112.638 114.401 1.00 105.39 ? 327 GLU A HG3  1 
ATOM 4813 N N    . LEU A 1 328 ? 69.709  109.304 115.514 1.00 128.87 ? 328 LEU A N    1 
ATOM 4814 C CA   . LEU A 1 328 ? 69.156  108.053 116.024 1.00 131.56 ? 328 LEU A CA   1 
ATOM 4815 C C    . LEU A 1 328 ? 68.095  107.493 115.086 1.00 137.04 ? 328 LEU A C    1 
ATOM 4816 O O    . LEU A 1 328 ? 68.026  106.277 114.870 1.00 135.32 ? 328 LEU A O    1 
ATOM 4817 C CB   . LEU A 1 328 ? 68.576  108.270 117.421 1.00 126.01 ? 328 LEU A CB   1 
ATOM 4818 H H    . LEU A 1 328 ? 69.558  109.991 116.010 1.00 124.49 ? 328 LEU A H    1 
ATOM 4819 H HA   . LEU A 1 328 ? 69.870  107.400 116.093 1.00 129.20 ? 328 LEU A HA   1 
ATOM 4820 N N    . SER A 1 329 ? 67.251  108.363 114.526 1.00 137.50 ? 329 SER A N    1 
ATOM 4821 C CA   . SER A 1 329 ? 66.208  107.894 113.619 1.00 137.60 ? 329 SER A CA   1 
ATOM 4822 C C    . SER A 1 329 ? 66.810  107.208 112.400 1.00 138.75 ? 329 SER A C    1 
ATOM 4823 O O    . SER A 1 329 ? 66.331  106.151 111.972 1.00 142.64 ? 329 SER A O    1 
ATOM 4824 C CB   . SER A 1 329 ? 65.323  109.064 113.190 1.00 133.87 ? 329 SER A CB   1 
ATOM 4825 O OG   . SER A 1 329 ? 65.916  109.788 112.126 1.00 131.66 ? 329 SER A OG   1 
ATOM 4826 H H    . SER A 1 329 ? 67.262  109.213 114.652 1.00 131.90 ? 329 SER A H    1 
ATOM 4827 H HA   . SER A 1 329 ? 65.652  107.249 114.082 1.00 136.73 ? 329 SER A HA   1 
ATOM 4828 H HB2  . SER A 1 329 ? 64.466  108.718 112.895 1.00 133.81 ? 329 SER A HB2  1 
ATOM 4829 H HB3  . SER A 1 329 ? 65.199  109.659 113.946 1.00 131.81 ? 329 SER A HB3  1 
ATOM 4830 H HG   . SER A 1 329 ? 66.671  110.075 112.359 1.00 130.11 ? 329 SER A HG   1 
ATOM 4831 N N    . VAL A 1 330 ? 67.862  107.792 111.829 1.00 137.69 ? 330 VAL A N    1 
ATOM 4832 C CA   . VAL A 1 330 ? 68.537  107.215 110.672 1.00 143.98 ? 330 VAL A CA   1 
ATOM 4833 C C    . VAL A 1 330 ? 69.857  106.605 111.122 1.00 145.07 ? 330 VAL A C    1 
ATOM 4834 O O    . VAL A 1 330 ? 70.881  107.293 111.193 1.00 145.05 ? 330 VAL A O    1 
ATOM 4835 C CB   . VAL A 1 330 ? 68.762  108.269 109.573 1.00 138.71 ? 330 VAL A CB   1 
ATOM 4836 H H    . VAL A 1 330 ? 68.207  108.533 112.097 1.00 134.81 ? 330 VAL A H    1 
ATOM 4837 H HA   . VAL A 1 330 ? 67.989  106.506 110.300 1.00 142.14 ? 330 VAL A HA   1 
ATOM 4838 N N    . GLY A 1 331 ? 69.840  105.311 111.429 1.00 144.74 ? 331 GLY A N    1 
ATOM 4839 C CA   . GLY A 1 331 ? 71.049  104.612 111.816 1.00 150.25 ? 331 GLY A CA   1 
ATOM 4840 C C    . GLY A 1 331 ? 71.860  104.183 110.612 1.00 156.76 ? 331 GLY A C    1 
ATOM 4841 O O    . GLY A 1 331 ? 71.875  103.002 110.254 1.00 156.36 ? 331 GLY A O    1 
ATOM 4842 H H    . GLY A 1 331 ? 69.136  104.817 111.419 1.00 143.72 ? 331 GLY A H    1 
ATOM 4843 H HA2  . GLY A 1 331 ? 71.597  105.190 112.369 1.00 147.80 ? 331 GLY A HA2  1 
ATOM 4844 H HA3  . GLY A 1 331 ? 70.817  103.822 112.330 1.00 148.63 ? 331 GLY A HA3  1 
ATOM 4845 N N    . GLN A 1 332 ? 72.529  105.142 109.975 1.00 156.89 ? 332 GLN A N    1 
ATOM 4846 C CA   . GLN A 1 332 ? 73.299  104.865 108.769 1.00 154.97 ? 332 GLN A CA   1 
ATOM 4847 C C    . GLN A 1 332 ? 74.217  103.669 108.979 1.00 154.95 ? 332 GLN A C    1 
ATOM 4848 O O    . GLN A 1 332 ? 75.139  103.715 109.798 1.00 150.44 ? 332 GLN A O    1 
ATOM 4849 C CB   . GLN A 1 332 ? 74.109  106.106 108.381 1.00 155.15 ? 332 GLN A CB   1 
ATOM 4850 C CG   . GLN A 1 332 ? 75.339  105.832 107.522 1.00 153.74 ? 332 GLN A CG   1 
ATOM 4851 C CD   . GLN A 1 332 ? 76.045  107.106 107.098 1.00 149.74 ? 332 GLN A CD   1 
ATOM 4852 O OE1  . GLN A 1 332 ? 75.466  108.191 107.133 1.00 152.81 ? 332 GLN A OE1  1 
ATOM 4853 N NE2  . GLN A 1 332 ? 77.305  106.979 106.696 1.00 141.08 ? 332 GLN A NE2  1 
ATOM 4854 H H    . GLN A 1 332 ? 72.552  105.965 110.224 1.00 152.89 ? 332 GLN A H    1 
ATOM 4855 H HA   . GLN A 1 332 ? 72.692  104.658 108.042 1.00 153.23 ? 332 GLN A HA   1 
ATOM 4856 H HB2  . GLN A 1 332 ? 73.533  106.707 107.883 1.00 153.84 ? 332 GLN A HB2  1 
ATOM 4857 H HB3  . GLN A 1 332 ? 74.411  106.544 109.192 1.00 153.63 ? 332 GLN A HB3  1 
ATOM 4858 H HG2  . GLN A 1 332 ? 75.977  105.305 108.028 1.00 151.90 ? 332 GLN A HG2  1 
ATOM 4859 H HG3  . GLN A 1 332 ? 75.070  105.354 106.722 1.00 153.61 ? 332 GLN A HG3  1 
ATOM 4860 H HE21 . GLN A 1 332 ? 77.678  106.204 106.686 1.00 145.76 ? 332 GLN A HE21 1 
ATOM 4861 H HE22 . GLN A 1 332 ? 77.749  107.672 106.446 1.00 145.24 ? 332 GLN A HE22 1 
ATOM 4862 N N    . ALA A 1 333 ? 73.956  102.597 108.231 1.00 156.49 ? 333 ALA A N    1 
ATOM 4863 C CA   . ALA A 1 333 ? 74.772  101.392 108.283 1.00 153.90 ? 333 ALA A CA   1 
ATOM 4864 C C    . ALA A 1 333 ? 75.754  101.392 107.124 1.00 151.13 ? 333 ALA A C    1 
ATOM 4865 O O    . ALA A 1 333 ? 75.333  101.590 105.975 1.00 148.39 ? 333 ALA A O    1 
ATOM 4866 C CB   . ALA A 1 333 ? 73.894  100.146 108.217 1.00 151.83 ? 333 ALA A CB   1 
ATOM 4867 H H    . ALA A 1 333 ? 73.301  102.546 107.677 1.00 154.98 ? 333 ALA A H    1 
ATOM 4868 H HA   . ALA A 1 333 ? 75.255  101.374 109.122 1.00 153.46 ? 333 ALA A HA   1 
ATOM 4869 H HB1  . ALA A 1 333 ? 74.461  99.359  108.252 1.00 151.35 ? 333 ALA A HB1  1 
ATOM 4870 H HB2  . ALA A 1 333 ? 73.284  100.149 108.971 1.00 152.92 ? 333 ALA A HB2  1 
ATOM 4871 H HB3  . ALA A 1 333 ? 73.394  100.156 107.386 1.00 152.30 ? 333 ALA A HB3  1 
ATOM 4872 N N    . PRO A 1 334 ? 77.050  101.193 107.358 1.00 150.15 ? 334 PRO A N    1 
ATOM 4873 C CA   . PRO A 1 334 ? 77.999  101.189 106.238 1.00 145.83 ? 334 PRO A CA   1 
ATOM 4874 C C    . PRO A 1 334 ? 77.572  100.208 105.156 1.00 138.40 ? 334 PRO A C    1 
ATOM 4875 O O    . PRO A 1 334 ? 77.260  99.047  105.430 1.00 136.07 ? 334 PRO A O    1 
ATOM 4876 C CB   . PRO A 1 334 ? 79.319  100.772 106.893 1.00 144.37 ? 334 PRO A CB   1 
ATOM 4877 C CG   . PRO A 1 334 ? 79.185  101.176 108.313 1.00 147.13 ? 334 PRO A CG   1 
ATOM 4878 C CD   . PRO A 1 334 ? 77.730  101.055 108.659 1.00 148.74 ? 334 PRO A CD   1 
ATOM 4879 H HA   . PRO A 1 334 ? 78.088  102.078 105.860 1.00 147.56 ? 334 PRO A HA   1 
ATOM 4880 H HB2  . PRO A 1 334 ? 79.434  99.812  106.818 1.00 144.09 ? 334 PRO A HB2  1 
ATOM 4881 H HB3  . PRO A 1 334 ? 80.056  101.241 106.471 1.00 144.60 ? 334 PRO A HB3  1 
ATOM 4882 H HG2  . PRO A 1 334 ? 79.715  100.582 108.868 1.00 147.32 ? 334 PRO A HG2  1 
ATOM 4883 H HG3  . PRO A 1 334 ? 79.483  102.093 108.418 1.00 146.21 ? 334 PRO A HG3  1 
ATOM 4884 H HD2  . PRO A 1 334 ? 77.544  100.186 109.048 1.00 148.75 ? 334 PRO A HD2  1 
ATOM 4885 H HD3  . PRO A 1 334 ? 77.470  101.775 109.254 1.00 148.38 ? 334 PRO A HD3  1 
ATOM 4886 N N    . ALA A 1 335 ? 77.560  100.685 103.915 1.00 128.34 ? 335 ALA A N    1 
ATOM 4887 C CA   . ALA A 1 335 ? 77.183  99.863  102.777 1.00 117.08 ? 335 ALA A CA   1 
ATOM 4888 C C    . ALA A 1 335 ? 78.409  99.148  102.228 1.00 112.13 ? 335 ALA A C    1 
ATOM 4889 O O    . ALA A 1 335 ? 79.493  99.730  102.132 1.00 107.61 ? 335 ALA A O    1 
ATOM 4890 C CB   . ALA A 1 335 ? 76.537  100.714 101.683 1.00 112.83 ? 335 ALA A CB   1 
ATOM 4891 H H    . ALA A 1 335 ? 77.768  101.493 103.707 1.00 130.70 ? 335 ALA A H    1 
ATOM 4892 H HA   . ALA A 1 335 ? 76.541  99.194  103.061 1.00 122.77 ? 335 ALA A HA   1 
ATOM 4893 H HB1  . ALA A 1 335 ? 75.742  101.138 102.042 1.00 119.73 ? 335 ALA A HB1  1 
ATOM 4894 H HB2  . ALA A 1 335 ? 77.170  101.390 101.393 1.00 115.96 ? 335 ALA A HB2  1 
ATOM 4895 H HB3  . ALA A 1 335 ? 76.299  100.142 100.937 1.00 113.46 ? 335 ALA A HB3  1 
ATOM 4896 N N    . SER A 1 336 ? 78.233  97.878  101.876 1.00 112.21 ? 336 SER A N    1 
ATOM 4897 C CA   . SER A 1 336 ? 79.324  97.086  101.336 1.00 109.41 ? 336 SER A CA   1 
ATOM 4898 C C    . SER A 1 336 ? 79.581  97.473  99.881  1.00 98.20  ? 336 SER A C    1 
ATOM 4899 O O    . SER A 1 336 ? 78.884  98.305  99.294  1.00 94.18  ? 336 SER A O    1 
ATOM 4900 C CB   . SER A 1 336 ? 79.010  95.597  101.462 1.00 100.66 ? 336 SER A CB   1 
ATOM 4901 H H    . SER A 1 336 ? 77.488  97.453  101.943 1.00 111.87 ? 336 SER A H    1 
ATOM 4902 H HA   . SER A 1 336 ? 80.131  97.268  101.843 1.00 109.71 ? 336 SER A HA   1 
ATOM 4903 N N    . LEU A 1 337 ? 80.606  96.859  99.288  1.00 94.65  ? 337 LEU A N    1 
ATOM 4904 C CA   . LEU A 1 337 ? 80.944  97.135  97.898  1.00 85.12  ? 337 LEU A CA   1 
ATOM 4905 C C    . LEU A 1 337 ? 79.924  96.569  96.921  1.00 91.69  ? 337 LEU A C    1 
ATOM 4906 O O    . LEU A 1 337 ? 79.992  96.889  95.729  1.00 92.97  ? 337 LEU A O    1 
ATOM 4907 C CB   . LEU A 1 337 ? 82.330  96.571  97.578  1.00 81.74  ? 337 LEU A CB   1 
ATOM 4908 C CG   . LEU A 1 337 ? 83.499  97.532  97.800  1.00 81.03  ? 337 LEU A CG   1 
ATOM 4909 C CD1  . LEU A 1 337 ? 83.439  98.151  99.190  1.00 76.52  ? 337 LEU A CD1  1 
ATOM 4910 C CD2  . LEU A 1 337 ? 84.825  96.822  97.584  1.00 85.21  ? 337 LEU A CD2  1 
ATOM 4911 H H    . LEU A 1 337 ? 81.116  96.281  99.670  1.00 95.85  ? 337 LEU A H    1 
ATOM 4912 H HA   . LEU A 1 337 ? 80.976  98.096  97.770  1.00 88.16  ? 337 LEU A HA   1 
ATOM 4913 H HB2  . LEU A 1 337 ? 82.483  95.793  98.135  1.00 86.49  ? 337 LEU A HB2  1 
ATOM 4914 H HB3  . LEU A 1 337 ? 82.344  96.308  96.644  1.00 82.43  ? 337 LEU A HB3  1 
ATOM 4915 H HG   . LEU A 1 337 ? 83.439  98.252  97.152  1.00 82.89  ? 337 LEU A HG   1 
ATOM 4916 H HD11 . LEU A 1 337 ? 84.262  98.638  99.352  1.00 77.57  ? 337 LEU A HD11 1 
ATOM 4917 H HD12 . LEU A 1 337 ? 82.683  98.758  99.234  1.00 80.67  ? 337 LEU A HD12 1 
ATOM 4918 H HD13 . LEU A 1 337 ? 83.337  97.445  99.846  1.00 82.86  ? 337 LEU A HD13 1 
ATOM 4919 H HD21 . LEU A 1 337 ? 85.548  97.445  97.755  1.00 84.98  ? 337 LEU A HD21 1 
ATOM 4920 H HD22 . LEU A 1 337 ? 84.884  96.070  98.195  1.00 86.37  ? 337 LEU A HD22 1 
ATOM 4921 H HD23 . LEU A 1 337 ? 84.869  96.508  96.667  1.00 84.92  ? 337 LEU A HD23 1 
ATOM 4922 N N    . GLY A 1 338 ? 78.983  95.746  97.390  1.00 96.87  ? 338 GLY A N    1 
ATOM 4923 C CA   . GLY A 1 338 ? 77.998  95.175  96.490  1.00 101.45 ? 338 GLY A CA   1 
ATOM 4924 C C    . GLY A 1 338 ? 77.199  96.222  95.740  1.00 102.30 ? 338 GLY A C    1 
ATOM 4925 O O    . GLY A 1 338 ? 76.748  95.978  94.618  1.00 105.12 ? 338 GLY A O    1 
ATOM 4926 H H    . GLY A 1 338 ? 78.898  95.509  98.213  1.00 96.10  ? 338 GLY A H    1 
ATOM 4927 H HA2  . GLY A 1 338 ? 78.445  94.609  95.841  1.00 100.35 ? 338 GLY A HA2  1 
ATOM 4928 H HA3  . GLY A 1 338 ? 77.379  94.627  96.998  1.00 99.60  ? 338 GLY A HA3  1 
ATOM 4929 N N    . THR A 1 339 ? 77.013  97.396  96.341  1.00 102.41 ? 339 THR A N    1 
ATOM 4930 C CA   . THR A 1 339 ? 76.280  98.489  95.718  1.00 104.45 ? 339 THR A CA   1 
ATOM 4931 C C    . THR A 1 339 ? 77.200  99.561  95.147  1.00 96.37  ? 339 THR A C    1 
ATOM 4932 O O    . THR A 1 339 ? 76.724  100.645 94.793  1.00 101.47 ? 339 THR A O    1 
ATOM 4933 C CB   . THR A 1 339 ? 75.316  99.122  96.725  1.00 106.72 ? 339 THR A CB   1 
ATOM 4934 O OG1  . THR A 1 339 ? 76.043  99.981  97.613  1.00 102.57 ? 339 THR A OG1  1 
ATOM 4935 C CG2  . THR A 1 339 ? 74.600  98.048  97.533  1.00 104.48 ? 339 THR A CG2  1 
ATOM 4936 H H    . THR A 1 339 ? 77.308  97.585  97.126  1.00 100.67 ? 339 THR A H    1 
ATOM 4937 H HA   . THR A 1 339 ? 75.750  98.136  94.987  1.00 103.97 ? 339 THR A HA   1 
ATOM 4938 H HB   . THR A 1 339 ? 74.650  99.642  96.249  1.00 104.77 ? 339 THR A HB   1 
ATOM 4939 H HG1  . THR A 1 339 ? 76.625  99.539  98.028  1.00 102.17 ? 339 THR A HG1  1 
ATOM 4940 H HG21 . THR A 1 339 ? 75.212  97.643  98.167  1.00 103.49 ? 339 THR A HG21 1 
ATOM 4941 H HG22 . THR A 1 339 ? 73.859  98.443  98.019  1.00 103.60 ? 339 THR A HG22 1 
ATOM 4942 H HG23 . THR A 1 339 ? 74.256  97.362  96.940  1.00 102.80 ? 339 THR A HG23 1 
ATOM 4943 N N    . LEU A 1 340 ? 78.502  99.288  95.050  1.00 89.37  ? 340 LEU A N    1 
ATOM 4944 C CA   . LEU A 1 340 ? 79.465  100.252 94.533  1.00 84.55  ? 340 LEU A CA   1 
ATOM 4945 C C    . LEU A 1 340 ? 80.045  99.816  93.193  1.00 90.53  ? 340 LEU A C    1 
ATOM 4946 O O    . LEU A 1 340 ? 79.972  100.563 92.214  1.00 92.27  ? 340 LEU A O    1 
ATOM 4947 C CB   . LEU A 1 340 ? 80.591  100.466 95.554  1.00 78.58  ? 340 LEU A CB   1 
ATOM 4948 C CG   . LEU A 1 340 ? 81.754  101.353 95.096  1.00 74.90  ? 340 LEU A CG   1 
ATOM 4949 C CD1  . LEU A 1 340 ? 81.250  102.684 94.555  1.00 72.24  ? 340 LEU A CD1  1 
ATOM 4950 C CD2  . LEU A 1 340 ? 82.736  101.575 96.234  1.00 75.85  ? 340 LEU A CD2  1 
ATOM 4951 H H    . LEU A 1 340 ? 78.855  98.539  95.281  1.00 92.66  ? 340 LEU A H    1 
ATOM 4952 H HA   . LEU A 1 340 ? 79.019  101.102 94.399  1.00 87.94  ? 340 LEU A HA   1 
ATOM 4953 H HB2  . LEU A 1 340 ? 80.209  100.877 96.346  1.00 83.35  ? 340 LEU A HB2  1 
ATOM 4954 H HB3  . LEU A 1 340 ? 80.961  99.601  95.788  1.00 84.39  ? 340 LEU A HB3  1 
ATOM 4955 H HG   . LEU A 1 340 ? 82.230  100.903 94.381  1.00 79.02  ? 340 LEU A HG   1 
ATOM 4956 H HD11 . LEU A 1 340 ? 82.013  103.242 94.336  1.00 70.69  ? 340 LEU A HD11 1 
ATOM 4957 H HD12 . LEU A 1 340 ? 80.720  102.525 93.759  1.00 73.99  ? 340 LEU A HD12 1 
ATOM 4958 H HD13 . LEU A 1 340 ? 80.709  103.116 95.234  1.00 77.79  ? 340 LEU A HD13 1 
ATOM 4959 H HD21 . LEU A 1 340 ? 83.468  102.126 95.917  1.00 74.96  ? 340 LEU A HD21 1 
ATOM 4960 H HD22 . LEU A 1 340 ? 82.276  102.021 96.961  1.00 79.78  ? 340 LEU A HD22 1 
ATOM 4961 H HD23 . LEU A 1 340 ? 83.072  100.715 96.533  1.00 77.90  ? 340 LEU A HD23 1 
ATOM 4962 N N    . LEU A 1 341 ? 80.622  98.615  93.122  1.00 95.64  ? 341 LEU A N    1 
ATOM 4963 C CA   . LEU A 1 341 ? 81.220  98.139  91.882  1.00 94.73  ? 341 LEU A CA   1 
ATOM 4964 C C    . LEU A 1 341 ? 80.187  97.625  90.888  1.00 94.86  ? 341 LEU A C    1 
ATOM 4965 O O    . LEU A 1 341 ? 80.511  97.471  89.705  1.00 93.04  ? 341 LEU A O    1 
ATOM 4966 C CB   . LEU A 1 341 ? 82.229  97.027  92.178  1.00 90.66  ? 341 LEU A CB   1 
ATOM 4967 C CG   . LEU A 1 341 ? 83.553  97.425  92.837  1.00 86.09  ? 341 LEU A CG   1 
ATOM 4968 C CD1  . LEU A 1 341 ? 84.469  96.215  92.939  1.00 88.18  ? 341 LEU A CD1  1 
ATOM 4969 C CD2  . LEU A 1 341 ? 84.241  98.550  92.076  1.00 81.19  ? 341 LEU A CD2  1 
ATOM 4970 H H    . LEU A 1 341 ? 80.679  98.061  93.778  1.00 92.00  ? 341 LEU A H    1 
ATOM 4971 H HA   . LEU A 1 341 ? 81.689  98.874  91.459  1.00 92.20  ? 341 LEU A HA   1 
ATOM 4972 H HB2  . LEU A 1 341 ? 81.802  96.385  92.767  1.00 90.83  ? 341 LEU A HB2  1 
ATOM 4973 H HB3  . LEU A 1 341 ? 82.450  96.591  91.340  1.00 90.26  ? 341 LEU A HB3  1 
ATOM 4974 H HG   . LEU A 1 341 ? 83.374  97.741  93.737  1.00 86.87  ? 341 LEU A HG   1 
ATOM 4975 H HD11 . LEU A 1 341 ? 84.021  95.522  93.449  1.00 88.19  ? 341 LEU A HD11 1 
ATOM 4976 H HD12 . LEU A 1 341 ? 84.667  95.893  92.046  1.00 88.21  ? 341 LEU A HD12 1 
ATOM 4977 H HD13 . LEU A 1 341 ? 85.290  96.477  93.386  1.00 87.62  ? 341 LEU A HD13 1 
ATOM 4978 H HD21 . LEU A 1 341 ? 83.745  99.373  92.207  1.00 84.98  ? 341 LEU A HD21 1 
ATOM 4979 H HD22 . LEU A 1 341 ? 85.145  98.651  92.414  1.00 83.24  ? 341 LEU A HD22 1 
ATOM 4980 H HD23 . LEU A 1 341 ? 84.266  98.323  91.133  1.00 83.71  ? 341 LEU A HD23 1 
ATOM 4981 N N    . ARG A 1 342 ? 78.958  97.358  91.335  1.00 93.88  ? 342 ARG A N    1 
ATOM 4982 C CA   . ARG A 1 342 ? 77.964  96.769  90.444  1.00 100.34 ? 342 ARG A CA   1 
ATOM 4983 C C    . ARG A 1 342 ? 77.497  97.755  89.379  1.00 105.12 ? 342 ARG A C    1 
ATOM 4984 O O    . ARG A 1 342 ? 77.223  97.349  88.244  1.00 106.43 ? 342 ARG A O    1 
ATOM 4985 C CB   . ARG A 1 342 ? 76.774  96.258  91.256  1.00 98.15  ? 342 ARG A CB   1 
ATOM 4986 C CG   . ARG A 1 342 ? 77.029  94.925  91.952  1.00 100.51 ? 342 ARG A CG   1 
ATOM 4987 C CD   . ARG A 1 342 ? 77.136  93.778  90.957  1.00 104.25 ? 342 ARG A CD   1 
ATOM 4988 N NE   . ARG A 1 342 ? 78.510  93.323  90.777  1.00 106.67 ? 342 ARG A NE   1 
ATOM 4989 C CZ   . ARG A 1 342 ? 79.225  92.699  91.705  1.00 101.48 ? 342 ARG A CZ   1 
ATOM 4990 N NH1  . ARG A 1 342 ? 78.729  92.442  92.904  1.00 96.44  ? 342 ARG A NH1  1 
ATOM 4991 N NH2  . ARG A 1 342 ? 80.468  92.323  91.421  1.00 100.53 ? 342 ARG A NH2  1 
ATOM 4992 H H    . ARG A 1 342 ? 78.680  97.506  92.135  1.00 94.59  ? 342 ARG A H    1 
ATOM 4993 H HA   . ARG A 1 342 ? 78.364  96.011  89.989  1.00 100.75 ? 342 ARG A HA   1 
ATOM 4994 H HB2  . ARG A 1 342 ? 76.559  96.911  91.940  1.00 98.03  ? 342 ARG A HB2  1 
ATOM 4995 H HB3  . ARG A 1 342 ? 76.016  96.142  90.662  1.00 99.97  ? 342 ARG A HB3  1 
ATOM 4996 H HG2  . ARG A 1 342 ? 77.861  94.978  92.448  1.00 100.10 ? 342 ARG A HG2  1 
ATOM 4997 H HG3  . ARG A 1 342 ? 76.293  94.734  92.554  1.00 101.13 ? 342 ARG A HG3  1 
ATOM 4998 H HD2  . ARG A 1 342 ? 76.611  93.029  91.280  1.00 102.03 ? 342 ARG A HD2  1 
ATOM 4999 H HD3  . ARG A 1 342 ? 76.801  94.071  90.096  1.00 103.69 ? 342 ARG A HD3  1 
ATOM 5000 H HE   . ARG A 1 342 ? 78.885  93.474  90.019  1.00 104.02 ? 342 ARG A HE   1 
ATOM 5001 H HH11 . ARG A 1 342 ? 77.926  92.679  93.101  1.00 98.77  ? 342 ARG A HH11 1 
ATOM 5002 H HH12 . ARG A 1 342 ? 79.212  92.036  93.490  1.00 97.73  ? 342 ARG A HH12 1 
ATOM 5003 H HH21 . ARG A 1 342 ? 80.800  92.485  90.645  1.00 100.84 ? 342 ARG A HH21 1 
ATOM 5004 H HH22 . ARG A 1 342 ? 80.941  91.918  92.015  1.00 100.88 ? 342 ARG A HH22 1 
ATOM 5005 N N    . THR A 1 343 ? 77.402  99.035  89.713  1.00 105.07 ? 343 THR A N    1 
ATOM 5006 C CA   . THR A 1 343 ? 76.921  100.026 88.752  1.00 101.41 ? 343 THR A CA   1 
ATOM 5007 C C    . THR A 1 343 ? 77.967  100.246 87.664  1.00 103.77 ? 343 THR A C    1 
ATOM 5008 O O    . THR A 1 343 ? 79.084  100.680 87.975  1.00 97.05  ? 343 THR A O    1 
ATOM 5009 C CB   . THR A 1 343 ? 76.607  101.342 89.457  1.00 94.96  ? 343 THR A CB   1 
ATOM 5010 O OG1  . THR A 1 343 ? 77.664  101.667 90.369  1.00 94.68  ? 343 THR A OG1  1 
ATOM 5011 C CG2  . THR A 1 343 ? 75.293  101.240 90.219  1.00 97.26  ? 343 THR A CG2  1 
ATOM 5012 H H    . THR A 1 343 ? 77.606  99.356  90.483  1.00 99.73  ? 343 THR A H    1 
ATOM 5013 H HA   . THR A 1 343 ? 76.100  99.703  88.354  1.00 100.10 ? 343 THR A HA   1 
ATOM 5014 H HB   . THR A 1 343 ? 76.524  102.049 88.797  1.00 96.81  ? 343 THR A HB   1 
ATOM 5015 H HG1  . THR A 1 343 ? 77.626  101.168 91.044  1.00 95.90  ? 343 THR A HG1  1 
ATOM 5016 H HG21 . THR A 1 343 ? 74.569  101.044 89.604  1.00 97.14  ? 343 THR A HG21 1 
ATOM 5017 H HG22 . THR A 1 343 ? 75.346  100.530 90.878  1.00 99.04  ? 343 THR A HG22 1 
ATOM 5018 H HG23 . THR A 1 343 ? 75.106  102.077 90.670  1.00 97.26  ? 343 THR A HG23 1 
ATOM 5019 N N    . PRO A 1 344 ? 77.662  99.968  86.390  1.00 108.39 ? 344 PRO A N    1 
ATOM 5020 C CA   . PRO A 1 344 ? 78.695  100.126 85.350  1.00 95.98  ? 344 PRO A CA   1 
ATOM 5021 C C    . PRO A 1 344 ? 79.239  101.540 85.229  1.00 91.59  ? 344 PRO A C    1 
ATOM 5022 O O    . PRO A 1 344 ? 80.434  101.716 84.960  1.00 86.53  ? 344 PRO A O    1 
ATOM 5023 C CB   . PRO A 1 344 ? 77.974  99.684  84.068  1.00 99.96  ? 344 PRO A CB   1 
ATOM 5024 C CG   . PRO A 1 344 ? 76.833  98.850  84.523  1.00 103.69 ? 344 PRO A CG   1 
ATOM 5025 C CD   . PRO A 1 344 ? 76.417  99.391  85.852  1.00 105.34 ? 344 PRO A CD   1 
ATOM 5026 H HA   . PRO A 1 344 ? 79.429  99.521  85.520  1.00 96.54  ? 344 PRO A HA   1 
ATOM 5027 H HB2  . PRO A 1 344 ? 77.657  100.463 83.585  1.00 100.10 ? 344 PRO A HB2  1 
ATOM 5028 H HB3  . PRO A 1 344 ? 78.580  99.163  83.517  1.00 99.26  ? 344 PRO A HB3  1 
ATOM 5029 H HG2  . PRO A 1 344 ? 76.106  98.919  83.885  1.00 102.94 ? 344 PRO A HG2  1 
ATOM 5030 H HG3  . PRO A 1 344 ? 77.123  97.929  84.609  1.00 103.55 ? 344 PRO A HG3  1 
ATOM 5031 H HD2  . PRO A 1 344 ? 75.740  100.077 85.745  1.00 103.25 ? 344 PRO A HD2  1 
ATOM 5032 H HD3  . PRO A 1 344 ? 76.107  98.667  86.418  1.00 103.59 ? 344 PRO A HD3  1 
ATOM 5033 N N    . GLY A 1 345 ? 78.396  102.556 85.414  1.00 89.28  ? 345 GLY A N    1 
ATOM 5034 C CA   . GLY A 1 345 ? 78.843  103.922 85.202  1.00 86.07  ? 345 GLY A CA   1 
ATOM 5035 C C    . GLY A 1 345 ? 79.939  104.355 86.155  1.00 85.24  ? 345 GLY A C    1 
ATOM 5036 O O    . GLY A 1 345 ? 80.813  105.144 85.785  1.00 86.10  ? 345 GLY A O    1 
ATOM 5037 H H    . GLY A 1 345 ? 77.574  102.481 85.656  1.00 92.97  ? 345 GLY A H    1 
ATOM 5038 H HA2  . GLY A 1 345 ? 79.178  104.011 84.296  1.00 89.35  ? 345 GLY A HA2  1 
ATOM 5039 H HA3  . GLY A 1 345 ? 78.091  104.526 85.308  1.00 86.70  ? 345 GLY A HA3  1 
ATOM 5040 N N    . LEU A 1 346 ? 79.912  103.853 87.386  1.00 78.74  ? 346 LEU A N    1 
ATOM 5041 C CA   . LEU A 1 346 ? 80.839  104.281 88.424  1.00 71.87  ? 346 LEU A CA   1 
ATOM 5042 C C    . LEU A 1 346 ? 82.099  103.423 88.491  1.00 74.33  ? 346 LEU A C    1 
ATOM 5043 O O    . LEU A 1 346 ? 82.987  103.717 89.297  1.00 73.67  ? 346 LEU A O    1 
ATOM 5044 C CB   . LEU A 1 346 ? 80.125  104.267 89.781  1.00 71.33  ? 346 LEU A CB   1 
ATOM 5045 C CG   . LEU A 1 346 ? 80.555  105.299 90.828  1.00 71.95  ? 346 LEU A CG   1 
ATOM 5046 C CD1  . LEU A 1 346 ? 79.423  105.518 91.821  1.00 69.12  ? 346 LEU A CD1  1 
ATOM 5047 C CD2  . LEU A 1 346 ? 81.826  104.888 91.555  1.00 72.05  ? 346 LEU A CD2  1 
ATOM 5048 H H    . LEU A 1 346 ? 79.356  103.251 87.648  1.00 82.53  ? 346 LEU A H    1 
ATOM 5049 H HA   . LEU A 1 346 ? 81.112  105.194 88.243  1.00 75.73  ? 346 LEU A HA   1 
ATOM 5050 H HB2  . LEU A 1 346 ? 79.180  104.410 89.617  1.00 75.23  ? 346 LEU A HB2  1 
ATOM 5051 H HB3  . LEU A 1 346 ? 80.247  103.389 90.174  1.00 76.19  ? 346 LEU A HB3  1 
ATOM 5052 H HG   . LEU A 1 346 ? 80.727  106.143 90.382  1.00 75.04  ? 346 LEU A HG   1 
ATOM 5053 H HD11 . LEU A 1 346 ? 79.702  106.175 92.478  1.00 68.41  ? 346 LEU A HD11 1 
ATOM 5054 H HD12 . LEU A 1 346 ? 78.643  105.839 91.342  1.00 71.52  ? 346 LEU A HD12 1 
ATOM 5055 H HD13 . LEU A 1 346 ? 79.220  104.677 92.258  1.00 71.77  ? 346 LEU A HD13 1 
ATOM 5056 H HD21 . LEU A 1 346 ? 81.806  105.251 92.454  1.00 70.80  ? 346 LEU A HD21 1 
ATOM 5057 H HD22 . LEU A 1 346 ? 81.875  103.920 91.592  1.00 75.18  ? 346 LEU A HD22 1 
ATOM 5058 H HD23 . LEU A 1 346 ? 82.592  105.240 91.075  1.00 74.02  ? 346 LEU A HD23 1 
ATOM 5059 N N    . ARG A 1 347 ? 82.209  102.383 87.660  1.00 74.79  ? 347 ARG A N    1 
ATOM 5060 C CA   . ARG A 1 347 ? 83.373  101.504 87.728  1.00 70.91  ? 347 ARG A CA   1 
ATOM 5061 C C    . ARG A 1 347 ? 84.656  102.269 87.428  1.00 69.30  ? 347 ARG A C    1 
ATOM 5062 O O    . ARG A 1 347 ? 85.667  102.118 88.128  1.00 67.25  ? 347 ARG A O    1 
ATOM 5063 C CB   . ARG A 1 347 ? 83.212  100.341 86.747  1.00 77.96  ? 347 ARG A CB   1 
ATOM 5064 C CG   . ARG A 1 347 ? 82.126  99.346  87.119  1.00 80.57  ? 347 ARG A CG   1 
ATOM 5065 C CD   . ARG A 1 347 ? 81.838  98.375  85.982  1.00 86.84  ? 347 ARG A CD   1 
ATOM 5066 N NE   . ARG A 1 347 ? 82.641  97.163  86.075  1.00 86.83  ? 347 ARG A NE   1 
ATOM 5067 C CZ   . ARG A 1 347 ? 82.356  96.138  86.866  1.00 84.35  ? 347 ARG A CZ   1 
ATOM 5068 N NH1  . ARG A 1 347 ? 81.297  96.149  87.659  1.00 78.34  ? 347 ARG A NH1  1 
ATOM 5069 N NH2  . ARG A 1 347 ? 83.154  95.074  86.863  1.00 81.17  ? 347 ARG A NH2  1 
ATOM 5070 H H    . ARG A 1 347 ? 81.633  102.171 87.057  1.00 79.05  ? 347 ARG A H    1 
ATOM 5071 H HA   . ARG A 1 347 ? 83.442  101.138 88.624  1.00 74.24  ? 347 ARG A HA   1 
ATOM 5072 H HB2  . ARG A 1 347 ? 82.992  100.707 85.876  1.00 78.93  ? 347 ARG A HB2  1 
ATOM 5073 H HB3  . ARG A 1 347 ? 84.053  99.860  86.694  1.00 79.64  ? 347 ARG A HB3  1 
ATOM 5074 H HG2  . ARG A 1 347 ? 82.415  98.834  87.891  1.00 83.25  ? 347 ARG A HG2  1 
ATOM 5075 H HG3  . ARG A 1 347 ? 81.309  99.828  87.321  1.00 83.14  ? 347 ARG A HG3  1 
ATOM 5076 H HD2  . ARG A 1 347 ? 80.907  98.112  86.015  1.00 86.57  ? 347 ARG A HD2  1 
ATOM 5077 H HD3  . ARG A 1 347 ? 82.033  98.804  85.134  1.00 85.00  ? 347 ARG A HD3  1 
ATOM 5078 H HE   . ARG A 1 347 ? 83.365  97.124  85.612  1.00 84.34  ? 347 ARG A HE   1 
ATOM 5079 H HH11 . ARG A 1 347 ? 80.773  96.831  87.671  1.00 79.86  ? 347 ARG A HH11 1 
ATOM 5080 H HH12 . ARG A 1 347 ? 81.132  95.473  88.164  1.00 78.98  ? 347 ARG A HH12 1 
ATOM 5081 H HH21 . ARG A 1 347 ? 83.845  95.055  86.352  1.00 81.44  ? 347 ARG A HH21 1 
ATOM 5082 H HH22 . ARG A 1 347 ? 82.977  94.404  87.373  1.00 81.73  ? 347 ARG A HH22 1 
ATOM 5083 N N    . LEU A 1 348 ? 84.628  103.105 86.387  1.00 65.99  ? 348 LEU A N    1 
ATOM 5084 C CA   . LEU A 1 348 ? 85.844  103.781 85.950  1.00 61.70  ? 348 LEU A CA   1 
ATOM 5085 C C    . LEU A 1 348 ? 86.391  104.678 87.052  1.00 59.85  ? 348 LEU A C    1 
ATOM 5086 O O    . LEU A 1 348 ? 87.603  104.704 87.304  1.00 58.98  ? 348 LEU A O    1 
ATOM 5087 C CB   . LEU A 1 348 ? 85.553  104.598 84.688  1.00 57.74  ? 348 LEU A CB   1 
ATOM 5088 C CG   . LEU A 1 348 ? 86.615  105.612 84.257  1.00 61.77  ? 348 LEU A CG   1 
ATOM 5089 C CD1  . LEU A 1 348 ? 87.923  104.898 83.920  1.00 59.46  ? 348 LEU A CD1  1 
ATOM 5090 C CD2  . LEU A 1 348 ? 86.126  106.447 83.087  1.00 63.76  ? 348 LEU A CD2  1 
ATOM 5091 H H    . LEU A 1 348 ? 83.925  103.300 85.931  1.00 67.46  ? 348 LEU A H    1 
ATOM 5092 H HA   . LEU A 1 348 ? 86.516  103.118 85.730  1.00 63.75  ? 348 LEU A HA   1 
ATOM 5093 H HB2  . LEU A 1 348 ? 85.438  103.980 83.949  1.00 60.39  ? 348 LEU A HB2  1 
ATOM 5094 H HB3  . LEU A 1 348 ? 84.725  105.086 84.829  1.00 60.88  ? 348 LEU A HB3  1 
ATOM 5095 H HG   . LEU A 1 348 ? 86.787  106.216 84.997  1.00 62.02  ? 348 LEU A HG   1 
ATOM 5096 H HD11 . LEU A 1 348 ? 88.183  104.339 84.666  1.00 61.28  ? 348 LEU A HD11 1 
ATOM 5097 H HD12 . LEU A 1 348 ? 87.789  104.344 83.135  1.00 62.82  ? 348 LEU A HD12 1 
ATOM 5098 H HD13 . LEU A 1 348 ? 88.610  105.558 83.734  1.00 57.38  ? 348 LEU A HD13 1 
ATOM 5099 H HD21 . LEU A 1 348 ? 85.324  106.928 83.349  1.00 61.64  ? 348 LEU A HD21 1 
ATOM 5100 H HD22 . LEU A 1 348 ? 86.817  107.078 82.831  1.00 62.13  ? 348 LEU A HD22 1 
ATOM 5101 H HD23 . LEU A 1 348 ? 85.929  105.851 82.349  1.00 64.18  ? 348 LEU A HD23 1 
ATOM 5102 N N    . ARG A 1 349 ? 85.508  105.426 87.717  1.00 54.08  ? 349 ARG A N    1 
ATOM 5103 C CA   . ARG A 1 349 ? 85.946  106.345 88.761  1.00 53.05  ? 349 ARG A CA   1 
ATOM 5104 C C    . ARG A 1 349 ? 86.691  105.601 89.859  1.00 53.54  ? 349 ARG A C    1 
ATOM 5105 O O    . ARG A 1 349 ? 87.783  106.008 90.275  1.00 52.59  ? 349 ARG A O    1 
ATOM 5106 C CB   . ARG A 1 349 ? 84.738  107.079 89.338  1.00 55.90  ? 349 ARG A CB   1 
ATOM 5107 C CG   . ARG A 1 349 ? 84.917  108.581 89.468  1.00 56.90  ? 349 ARG A CG   1 
ATOM 5108 C CD   . ARG A 1 349 ? 83.581  109.278 89.667  1.00 55.78  ? 349 ARG A CD   1 
ATOM 5109 N NE   . ARG A 1 349 ? 82.628  108.944 88.615  1.00 51.18  ? 349 ARG A NE   1 
ATOM 5110 C CZ   . ARG A 1 349 ? 81.326  109.189 88.672  1.00 49.72  ? 349 ARG A CZ   1 
ATOM 5111 N NH1  . ARG A 1 349 ? 80.776  109.765 89.729  1.00 54.09  ? 349 ARG A NH1  1 
ATOM 5112 N NH2  . ARG A 1 349 ? 80.556  108.844 87.645  1.00 48.48  ? 349 ARG A NH2  1 
ATOM 5113 H H    . ARG A 1 349 ? 84.658  105.415 87.583  1.00 59.00  ? 349 ARG A H    1 
ATOM 5114 H HA   . ARG A 1 349 ? 86.547  107.001 88.374  1.00 55.97  ? 349 ARG A HA   1 
ATOM 5115 H HB2  . ARG A 1 349 ? 83.976  106.915 88.762  1.00 58.07  ? 349 ARG A HB2  1 
ATOM 5116 H HB3  . ARG A 1 349 ? 84.556  106.726 90.222  1.00 57.20  ? 349 ARG A HB3  1 
ATOM 5117 H HG2  . ARG A 1 349 ? 85.475  108.769 90.239  1.00 56.76  ? 349 ARG A HG2  1 
ATOM 5118 H HG3  . ARG A 1 349 ? 85.326  108.930 88.660  1.00 55.87  ? 349 ARG A HG3  1 
ATOM 5119 H HD2  . ARG A 1 349 ? 83.202  108.996 90.514  1.00 54.92  ? 349 ARG A HD2  1 
ATOM 5120 H HD3  . ARG A 1 349 ? 83.715  110.239 89.665  1.00 55.11  ? 349 ARG A HD3  1 
ATOM 5121 H HE   . ARG A 1 349 ? 82.939  108.608 87.887  1.00 52.80  ? 349 ARG A HE   1 
ATOM 5122 H HH11 . ARG A 1 349 ? 81.263  109.992 90.400  1.00 52.30  ? 349 ARG A HH11 1 
ATOM 5123 H HH12 . ARG A 1 349 ? 79.929  109.912 89.744  1.00 54.94  ? 349 ARG A HH12 1 
ATOM 5124 H HH21 . ARG A 1 349 ? 80.905  108.469 86.954  1.00 52.49  ? 349 ARG A HH21 1 
ATOM 5125 H HH22 . ARG A 1 349 ? 79.710  108.996 87.671  1.00 52.02  ? 349 ARG A HH22 1 
ATOM 5126 N N    . THR A 1 350 ? 86.112  104.498 90.336  1.00 56.06  ? 350 THR A N    1 
ATOM 5127 C CA   . THR A 1 350 ? 86.758  103.722 91.387  1.00 58.13  ? 350 THR A CA   1 
ATOM 5128 C C    . THR A 1 350 ? 88.084  103.153 90.907  1.00 52.09  ? 350 THR A C    1 
ATOM 5129 O O    . THR A 1 350 ? 89.077  103.167 91.646  1.00 49.68  ? 350 THR A O    1 
ATOM 5130 C CB   . THR A 1 350 ? 85.835  102.597 91.849  1.00 65.53  ? 350 THR A CB   1 
ATOM 5131 O OG1  . THR A 1 350 ? 85.329  101.892 90.709  1.00 58.91  ? 350 THR A OG1  1 
ATOM 5132 C CG2  . THR A 1 350 ? 84.675  103.156 92.655  1.00 70.16  ? 350 THR A CG2  1 
ATOM 5133 H H    . THR A 1 350 ? 85.359  104.179 90.066  1.00 59.82  ? 350 THR A H    1 
ATOM 5134 H HA   . THR A 1 350 ? 86.935  104.300 92.145  1.00 58.44  ? 350 THR A HA   1 
ATOM 5135 H HB   . THR A 1 350 ? 86.332  101.984 92.413  1.00 64.18  ? 350 THR A HB   1 
ATOM 5136 H HG1  . THR A 1 350 ? 85.961  101.530 90.291  1.00 62.45  ? 350 THR A HG1  1 
ATOM 5137 H HG21 . THR A 1 350 ? 84.969  103.365 93.556  1.00 69.09  ? 350 THR A HG21 1 
ATOM 5138 H HG22 . THR A 1 350 ? 84.340  103.965 92.238  1.00 66.18  ? 350 THR A HG22 1 
ATOM 5139 H HG23 . THR A 1 350 ? 83.958  102.504 92.702  1.00 69.91  ? 350 THR A HG23 1 
ATOM 5140 N N    . CYS A 1 351 ? 88.121  102.642 89.674  1.00 49.69  ? 351 CYS A N    1 
ATOM 5141 C CA   . CYS A 1 351 ? 89.356  102.056 89.165  1.00 47.53  ? 351 CYS A CA   1 
ATOM 5142 C C    . CYS A 1 351 ? 90.490  103.073 89.178  1.00 47.98  ? 351 CYS A C    1 
ATOM 5143 O O    . CYS A 1 351 ? 91.572  102.802 89.710  1.00 45.85  ? 351 CYS A O    1 
ATOM 5144 C CB   . CYS A 1 351 ? 89.136  101.507 87.755  1.00 47.90  ? 351 CYS A CB   1 
ATOM 5145 S SG   . CYS A 1 351 ? 90.657  101.029 86.903  1.00 65.19  ? 351 CYS A SG   1 
ATOM 5146 H H    . CYS A 1 351 ? 87.458  102.623 89.126  1.00 54.85  ? 351 CYS A H    1 
ATOM 5147 H HA   . CYS A 1 351 ? 89.614  101.319 89.739  1.00 50.13  ? 351 CYS A HA   1 
ATOM 5148 H HB2  . CYS A 1 351 ? 88.575  100.718 87.818  1.00 52.06  ? 351 CYS A HB2  1 
ATOM 5149 H HB3  . CYS A 1 351 ? 88.694  102.184 87.219  1.00 50.96  ? 351 CYS A HB3  1 
ATOM 5150 H HG   . CYS A 1 351 ? 90.381  100.587 85.822  1.00 65.09  ? 351 CYS A HG   1 
ATOM 5151 N N    . ILE A 1 352 ? 90.255  104.264 88.620  1.00 46.14  ? 352 ILE A N    1 
ATOM 5152 C CA   . ILE A 1 352 ? 91.333  105.256 88.572  1.00 42.29  ? 352 ILE A CA   1 
ATOM 5153 C C    . ILE A 1 352 ? 91.655  105.805 89.960  1.00 44.35  ? 352 ILE A C    1 
ATOM 5154 O O    . ILE A 1 352 ? 92.823  106.080 90.267  1.00 41.33  ? 352 ILE A O    1 
ATOM 5155 C CB   . ILE A 1 352 ? 91.048  106.388 87.562  1.00 43.96  ? 352 ILE A CB   1 
ATOM 5156 C CG1  . ILE A 1 352 ? 90.227  105.908 86.358  1.00 43.73  ? 352 ILE A CG1  1 
ATOM 5157 C CG2  . ILE A 1 352 ? 92.354  107.035 87.122  1.00 44.91  ? 352 ILE A CG2  1 
ATOM 5158 C CD1  . ILE A 1 352 ? 91.010  105.000 85.416  1.00 43.03  ? 352 ILE A CD1  1 
ATOM 5159 H H    . ILE A 1 352 ? 89.501  104.515 88.297  1.00 49.20  ? 352 ILE A H    1 
ATOM 5160 H HA   . ILE A 1 352 ? 92.132  104.803 88.262  1.00 44.21  ? 352 ILE A HA   1 
ATOM 5161 H HB   . ILE A 1 352 ? 90.522  107.061 88.021  1.00 45.45  ? 352 ILE A HB   1 
ATOM 5162 H HG12 . ILE A 1 352 ? 89.449  105.435 86.650  1.00 47.22  ? 352 ILE A HG12 1 
ATOM 5163 H HG13 . ILE A 1 352 ? 89.954  106.682 85.843  1.00 47.11  ? 352 ILE A HG13 1 
ATOM 5164 H HG21 . ILE A 1 352 ? 92.172  107.681 86.423  1.00 47.79  ? 352 ILE A HG21 1 
ATOM 5165 H HG22 . ILE A 1 352 ? 92.748  107.484 87.887  1.00 43.55  ? 352 ILE A HG22 1 
ATOM 5166 H HG23 . ILE A 1 352 ? 92.958  106.351 86.795  1.00 42.69  ? 352 ILE A HG23 1 
ATOM 5167 H HD11 . ILE A 1 352 ? 90.398  104.447 84.915  1.00 44.94  ? 352 ILE A HD11 1 
ATOM 5168 H HD12 . ILE A 1 352 ? 91.519  105.547 84.796  1.00 45.16  ? 352 ILE A HD12 1 
ATOM 5169 H HD13 . ILE A 1 352 ? 91.601  104.434 85.938  1.00 43.40  ? 352 ILE A HD13 1 
ATOM 5170 N N    . SER A 1 353 ? 90.652  105.993 90.821  1.00 50.79  ? 353 SER A N    1 
ATOM 5171 C CA   . SER A 1 353 ? 90.957  106.476 92.166  1.00 53.63  ? 353 SER A CA   1 
ATOM 5172 C C    . SER A 1 353 ? 91.871  105.496 92.893  1.00 51.64  ? 353 SER A C    1 
ATOM 5173 O O    . SER A 1 353 ? 92.885  105.889 93.491  1.00 54.73  ? 353 SER A O    1 
ATOM 5174 C CB   . SER A 1 353 ? 89.666  106.698 92.954  1.00 56.81  ? 353 SER A CB   1 
ATOM 5175 O OG   . SER A 1 353 ? 89.892  106.544 94.344  1.00 60.85  ? 353 SER A OG   1 
ATOM 5176 H H    . SER A 1 353 ? 89.817  105.856 90.658  1.00 50.54  ? 353 SER A H    1 
ATOM 5177 H HA   . SER A 1 353 ? 91.418  107.326 92.100  1.00 52.10  ? 353 SER A HA   1 
ATOM 5178 H HB2  . SER A 1 353 ? 89.350  107.601 92.790  1.00 54.44  ? 353 SER A HB2  1 
ATOM 5179 H HB3  . SER A 1 353 ? 88.999  106.055 92.666  1.00 54.43  ? 353 SER A HB3  1 
ATOM 5180 H HG   . SER A 1 353 ? 89.198  106.738 94.774  1.00 58.93  ? 353 SER A HG   1 
ATOM 5181 N N    . THR A 1 354 ? 91.538  104.205 92.830  1.00 42.53  ? 354 THR A N    1 
ATOM 5182 C CA   . THR A 1 354 ? 92.370  103.196 93.472  1.00 44.73  ? 354 THR A CA   1 
ATOM 5183 C C    . THR A 1 354 ? 93.745  103.137 92.822  1.00 46.55  ? 354 THR A C    1 
ATOM 5184 O O    . THR A 1 354 ? 94.757  102.946 93.507  1.00 48.72  ? 354 THR A O    1 
ATOM 5185 C CB   . THR A 1 354 ? 91.679  101.834 93.401  1.00 48.64  ? 354 THR A CB   1 
ATOM 5186 O OG1  . THR A 1 354 ? 90.324  101.960 93.851  1.00 54.04  ? 354 THR A OG1  1 
ATOM 5187 C CG2  . THR A 1 354 ? 92.396  100.826 94.276  1.00 56.02  ? 354 THR A CG2  1 
ATOM 5188 H H    . THR A 1 354 ? 90.846  103.894 92.424  1.00 46.66  ? 354 THR A H    1 
ATOM 5189 H HA   . THR A 1 354 ? 92.485  103.430 94.406  1.00 47.64  ? 354 THR A HA   1 
ATOM 5190 H HB   . THR A 1 354 ? 91.689  101.511 92.486  1.00 49.55  ? 354 THR A HB   1 
ATOM 5191 H HG1  . THR A 1 354 ? 89.970  101.201 93.914  1.00 51.25  ? 354 THR A HG1  1 
ATOM 5192 H HG21 . THR A 1 354 ? 91.963  99.961  94.207  1.00 53.46  ? 354 THR A HG21 1 
ATOM 5193 H HG22 . THR A 1 354 ? 93.322  100.738 94.002  1.00 51.83  ? 354 THR A HG22 1 
ATOM 5194 H HG23 . THR A 1 354 ? 92.364  101.121 95.198  1.00 57.00  ? 354 THR A HG23 1 
ATOM 5195 N N    . LEU A 1 355 ? 93.802  103.299 91.498  1.00 44.46  ? 355 LEU A N    1 
ATOM 5196 C CA   . LEU A 1 355 ? 95.082  103.295 90.800  1.00 35.84  ? 355 LEU A CA   1 
ATOM 5197 C C    . LEU A 1 355 ? 95.986  104.402 91.323  1.00 36.14  ? 355 LEU A C    1 
ATOM 5198 O O    . LEU A 1 355 ? 97.173  104.181 91.577  1.00 35.54  ? 355 LEU A O    1 
ATOM 5199 C CB   . LEU A 1 355 ? 94.850  103.450 89.296  1.00 35.07  ? 355 LEU A CB   1 
ATOM 5200 C CG   . LEU A 1 355 ? 96.035  103.182 88.366  1.00 36.05  ? 355 LEU A CG   1 
ATOM 5201 C CD1  . LEU A 1 355 ? 96.036  101.737 87.894  1.00 35.25  ? 355 LEU A CD1  1 
ATOM 5202 C CD2  . LEU A 1 355 ? 96.005  104.130 87.177  1.00 34.79  ? 355 LEU A CD2  1 
ATOM 5203 H H    . LEU A 1 355 ? 93.118  103.413 90.989  1.00 44.83  ? 355 LEU A H    1 
ATOM 5204 H HA   . LEU A 1 355 ? 95.525  102.446 90.952  1.00 38.18  ? 355 LEU A HA   1 
ATOM 5205 H HB2  . LEU A 1 355 ? 94.143  102.837 89.038  1.00 37.62  ? 355 LEU A HB2  1 
ATOM 5206 H HB3  . LEU A 1 355 ? 94.557  104.359 89.129  1.00 40.50  ? 355 LEU A HB3  1 
ATOM 5207 H HG   . LEU A 1 355 ? 96.860  103.338 88.851  1.00 36.65  ? 355 LEU A HG   1 
ATOM 5208 H HD11 . LEU A 1 355 ? 96.795  101.598 87.306  1.00 35.59  ? 355 LEU A HD11 1 
ATOM 5209 H HD12 . LEU A 1 355 ? 96.102  101.152 88.665  1.00 35.59  ? 355 LEU A HD12 1 
ATOM 5210 H HD13 . LEU A 1 355 ? 95.211  101.561 87.414  1.00 36.05  ? 355 LEU A HD13 1 
ATOM 5211 H HD21 . LEU A 1 355 ? 96.759  103.936 86.598  1.00 35.75  ? 355 LEU A HD21 1 
ATOM 5212 H HD22 . LEU A 1 355 ? 95.175  104.002 86.691  1.00 33.28  ? 355 LEU A HD22 1 
ATOM 5213 H HD23 . LEU A 1 355 ? 96.062  105.044 87.498  1.00 34.50  ? 355 LEU A HD23 1 
ATOM 5214 N N    . CYS A 1 356 ? 95.437  105.606 91.493  1.00 41.99  ? 356 CYS A N    1 
ATOM 5215 C CA   . CYS A 1 356 ? 96.239  106.720 91.994  1.00 42.57  ? 356 CYS A CA   1 
ATOM 5216 C C    . CYS A 1 356 ? 96.694  106.473 93.428  1.00 45.14  ? 356 CYS A C    1 
ATOM 5217 O O    . CYS A 1 356 ? 97.867  106.696 93.772  1.00 45.43  ? 356 CYS A O    1 
ATOM 5218 C CB   . CYS A 1 356 ? 95.443  108.022 91.903  1.00 39.40  ? 356 CYS A CB   1 
ATOM 5219 S SG   . CYS A 1 356 ? 95.084  108.557 90.216  1.00 53.85  ? 356 CYS A SG   1 
ATOM 5220 H H    . CYS A 1 356 ? 94.615  105.800 91.331  1.00 43.06  ? 356 CYS A H    1 
ATOM 5221 H HA   . CYS A 1 356 ? 97.031  106.812 91.442  1.00 42.66  ? 356 CYS A HA   1 
ATOM 5222 H HB2  . CYS A 1 356 ? 94.596  107.900 92.359  1.00 41.85  ? 356 CYS A HB2  1 
ATOM 5223 H HB3  . CYS A 1 356 ? 95.950  108.726 92.336  1.00 41.18  ? 356 CYS A HB3  1 
ATOM 5224 H HG   . CYS A 1 356 ? 94.492  107.694 89.630  1.00 45.62  ? 356 CYS A HG   1 
ATOM 5225 N N    . TRP A 1 357 ? 95.774  106.017 94.285  1.00 43.48  ? 357 TRP A N    1 
ATOM 5226 C CA   . TRP A 1 357 ? 96.151  105.729 95.666  1.00 43.83  ? 357 TRP A CA   1 
ATOM 5227 C C    . TRP A 1 357 ? 97.304  104.736 95.716  1.00 42.98  ? 357 TRP A C    1 
ATOM 5228 O O    . TRP A 1 357 ? 98.310  104.967 96.401  1.00 46.32  ? 357 TRP A O    1 
ATOM 5229 C CB   . TRP A 1 357 ? 94.953  105.165 96.431  1.00 48.63  ? 357 TRP A CB   1 
ATOM 5230 C CG   . TRP A 1 357 ? 94.008  106.188 96.981  1.00 56.13  ? 357 TRP A CG   1 
ATOM 5231 C CD1  . TRP A 1 357 ? 92.792  106.532 96.472  1.00 57.10  ? 357 TRP A CD1  1 
ATOM 5232 C CD2  . TRP A 1 357 ? 94.189  106.984 98.157  1.00 59.37  ? 357 TRP A CD2  1 
ATOM 5233 N NE1  . TRP A 1 357 ? 92.206  107.495 97.252  1.00 55.31  ? 357 TRP A NE1  1 
ATOM 5234 C CE2  . TRP A 1 357 ? 93.044  107.791 98.294  1.00 59.87  ? 357 TRP A CE2  1 
ATOM 5235 C CE3  . TRP A 1 357 ? 95.211  107.095 99.104  1.00 56.51  ? 357 TRP A CE3  1 
ATOM 5236 C CZ2  . TRP A 1 357 ? 92.891  108.698 99.339  1.00 56.17  ? 357 TRP A CZ2  1 
ATOM 5237 C CZ3  . TRP A 1 357 ? 95.058  107.996 100.141 1.00 59.55  ? 357 TRP A CZ3  1 
ATOM 5238 C CH2  . TRP A 1 357 ? 93.906  108.786 100.250 1.00 58.49  ? 357 TRP A CH2  1 
ATOM 5239 H H    . TRP A 1 357 ? 94.949  105.872 94.098  1.00 45.32  ? 357 TRP A H    1 
ATOM 5240 H HA   . TRP A 1 357 ? 96.438  106.548 96.101  1.00 46.57  ? 357 TRP A HA   1 
ATOM 5241 H HB2  . TRP A 1 357 ? 94.450  104.591 95.831  1.00 48.48  ? 357 TRP A HB2  1 
ATOM 5242 H HB3  . TRP A 1 357 ? 95.284  104.639 97.175  1.00 50.87  ? 357 TRP A HB3  1 
ATOM 5243 H HD1  . TRP A 1 357 ? 92.410  106.168 95.708  1.00 54.36  ? 357 TRP A HD1  1 
ATOM 5244 H HE1  . TRP A 1 357 ? 91.438  107.851 97.107  1.00 54.95  ? 357 TRP A HE1  1 
ATOM 5245 H HE3  . TRP A 1 357 ? 95.978  106.574 99.037  1.00 54.21  ? 357 TRP A HE3  1 
ATOM 5246 H HZ2  . TRP A 1 357 ? 92.128  109.224 99.413  1.00 55.38  ? 357 TRP A HZ2  1 
ATOM 5247 H HZ3  . TRP A 1 357 ? 95.730  108.079 100.778 1.00 57.56  ? 357 TRP A HZ3  1 
ATOM 5248 H HH2  . TRP A 1 357 ? 93.829  109.384 100.958 1.00 57.14  ? 357 TRP A HH2  1 
ATOM 5249 N N    . PHE A 1 358 ? 97.179  103.634 94.975  1.00 42.09  ? 358 PHE A N    1 
ATOM 5250 C CA   . PHE A 1 358 ? 98.216  102.611 94.973  1.00 44.09  ? 358 PHE A CA   1 
ATOM 5251 C C    . PHE A 1 358 ? 99.518  103.144 94.397  1.00 47.42  ? 358 PHE A C    1 
ATOM 5252 O O    . PHE A 1 358 ? 100.598 102.847 94.915  1.00 44.36  ? 358 PHE A O    1 
ATOM 5253 C CB   . PHE A 1 358 ? 97.746  101.395 94.175  1.00 40.04  ? 358 PHE A CB   1 
ATOM 5254 C CG   . PHE A 1 358 ? 98.864  100.491 93.745  1.00 40.01  ? 358 PHE A CG   1 
ATOM 5255 C CD1  . PHE A 1 358 ? 99.356  99.521  94.599  1.00 49.55  ? 358 PHE A CD1  1 
ATOM 5256 C CD2  . PHE A 1 358 ? 99.437  100.625 92.492  1.00 43.39  ? 358 PHE A CD2  1 
ATOM 5257 C CE1  . PHE A 1 358 ? 100.390 98.695  94.204  1.00 54.57  ? 358 PHE A CE1  1 
ATOM 5258 C CE2  . PHE A 1 358 ? 100.472 99.804  92.095  1.00 54.61  ? 358 PHE A CE2  1 
ATOM 5259 C CZ   . PHE A 1 358 ? 100.949 98.838  92.953  1.00 57.81  ? 358 PHE A CZ   1 
ATOM 5260 H H    . PHE A 1 358 ? 96.507  103.460 94.470  1.00 43.43  ? 358 PHE A H    1 
ATOM 5261 H HA   . PHE A 1 358 ? 98.382  102.326 95.884  1.00 43.94  ? 358 PHE A HA   1 
ATOM 5262 H HB2  . PHE A 1 358 ? 97.142  100.876 94.729  1.00 43.12  ? 358 PHE A HB2  1 
ATOM 5263 H HB3  . PHE A 1 358 ? 97.283  101.701 93.380  1.00 42.09  ? 358 PHE A HB3  1 
ATOM 5264 H HD1  . PHE A 1 358 ? 98.983  99.421  95.445  1.00 49.00  ? 358 PHE A HD1  1 
ATOM 5265 H HD2  . PHE A 1 358 ? 99.118  101.277 91.909  1.00 43.82  ? 358 PHE A HD2  1 
ATOM 5266 H HE1  . PHE A 1 358 ? 100.711 98.044  94.785  1.00 53.27  ? 358 PHE A HE1  1 
ATOM 5267 H HE2  . PHE A 1 358 ? 100.846 99.902  91.249  1.00 52.15  ? 358 PHE A HE2  1 
ATOM 5268 H HZ   . PHE A 1 358 ? 101.645 98.282  92.688  1.00 55.17  ? 358 PHE A HZ   1 
ATOM 5269 N N    . ALA A 1 359 ? 99.440  103.915 93.312  1.00 48.86  ? 359 ALA A N    1 
ATOM 5270 C CA   . ALA A 1 359 ? 100.650 104.434 92.690  1.00 39.27  ? 359 ALA A CA   1 
ATOM 5271 C C    . ALA A 1 359 ? 101.443 105.267 93.682  1.00 39.70  ? 359 ALA A C    1 
ATOM 5272 O O    . ALA A 1 359 ? 102.661 105.089 93.830  1.00 43.00  ? 359 ALA A O    1 
ATOM 5273 C CB   . ALA A 1 359 ? 100.291 105.253 91.451  1.00 35.73  ? 359 ALA A CB   1 
ATOM 5274 H H    . ALA A 1 359 ? 98.707  104.150 92.926  1.00 44.93  ? 359 ALA A H    1 
ATOM 5275 H HA   . ALA A 1 359 ? 101.207 103.691 92.410  1.00 41.57  ? 359 ALA A HA   1 
ATOM 5276 H HB1  . ALA A 1 359 ? 99.826  104.680 90.820  1.00 38.12  ? 359 ALA A HB1  1 
ATOM 5277 H HB2  . ALA A 1 359 ? 99.716  105.989 91.713  1.00 39.46  ? 359 ALA A HB2  1 
ATOM 5278 H HB3  . ALA A 1 359 ? 101.104 105.596 91.049  1.00 36.88  ? 359 ALA A HB3  1 
ATOM 5279 N N    . PHE A 1 360 ? 100.765 106.166 94.403  1.00 37.78  ? 360 PHE A N    1 
ATOM 5280 C CA   . PHE A 1 360 ? 101.508 106.973 95.364  1.00 43.27  ? 360 PHE A CA   1 
ATOM 5281 C C    . PHE A 1 360 ? 102.028 106.124 96.514  1.00 47.80  ? 360 PHE A C    1 
ATOM 5282 O O    . PHE A 1 360 ? 103.209 106.228 96.874  1.00 51.07  ? 360 PHE A O    1 
ATOM 5283 C CB   . PHE A 1 360 ? 100.651 108.106 95.925  1.00 46.71  ? 360 PHE A CB   1 
ATOM 5284 C CG   . PHE A 1 360 ? 100.902 108.376 97.384  1.00 52.40  ? 360 PHE A CG   1 
ATOM 5285 C CD1  . PHE A 1 360 ? 101.945 109.195 97.779  1.00 57.05  ? 360 PHE A CD1  1 
ATOM 5286 C CD2  . PHE A 1 360 ? 100.099 107.810 98.359  1.00 55.47  ? 360 PHE A CD2  1 
ATOM 5287 C CE1  . PHE A 1 360 ? 102.185 109.443 99.117  1.00 58.34  ? 360 PHE A CE1  1 
ATOM 5288 C CE2  . PHE A 1 360 ? 100.334 108.054 99.696  1.00 55.90  ? 360 PHE A CE2  1 
ATOM 5289 C CZ   . PHE A 1 360 ? 101.377 108.873 100.075 1.00 56.93  ? 360 PHE A CZ   1 
ATOM 5290 H H    . PHE A 1 360 ? 99.919  106.314 94.365  1.00 41.39  ? 360 PHE A H    1 
ATOM 5291 H HA   . PHE A 1 360 ? 102.270 107.370 94.914  1.00 44.49  ? 360 PHE A HA   1 
ATOM 5292 H HB2  . PHE A 1 360 ? 100.858 108.919 95.437  1.00 47.24  ? 360 PHE A HB2  1 
ATOM 5293 H HB3  . PHE A 1 360 ? 99.714  107.888 95.815  1.00 47.35  ? 360 PHE A HB3  1 
ATOM 5294 H HD1  . PHE A 1 360 ? 102.493 109.581 97.135  1.00 54.47  ? 360 PHE A HD1  1 
ATOM 5295 H HD2  . PHE A 1 360 ? 99.395  107.255 98.110  1.00 53.39  ? 360 PHE A HD2  1 
ATOM 5296 H HE1  . PHE A 1 360 ? 102.888 109.996 99.368  1.00 56.23  ? 360 PHE A HE1  1 
ATOM 5297 H HE2  . PHE A 1 360 ? 99.786  107.667 100.338 1.00 53.43  ? 360 PHE A HE2  1 
ATOM 5298 H HZ   . PHE A 1 360 ? 101.535 109.040 100.977 1.00 55.37  ? 360 PHE A HZ   1 
ATOM 5299 N N    . GLY A 1 361 ? 101.187 105.248 97.072  1.00 52.04  ? 361 GLY A N    1 
ATOM 5300 C CA   . GLY A 1 361 ? 101.610 104.482 98.229  1.00 52.74  ? 361 GLY A CA   1 
ATOM 5301 C C    . GLY A 1 361 ? 102.773 103.567 97.920  1.00 53.26  ? 361 GLY A C    1 
ATOM 5302 O O    . GLY A 1 361 ? 103.588 103.273 98.798  1.00 54.68  ? 361 GLY A O    1 
ATOM 5303 H H    . GLY A 1 361 ? 100.390 105.080 96.796  1.00 49.66  ? 361 GLY A H    1 
ATOM 5304 H HA2  . GLY A 1 361 ? 101.882 105.088 98.937  1.00 51.25  ? 361 GLY A HA2  1 
ATOM 5305 H HA3  . GLY A 1 361 ? 100.872 103.944 98.550  1.00 51.64  ? 361 GLY A HA3  1 
ATOM 5306 N N    . PHE A 1 362 ? 102.871 103.111 96.675  1.00 49.43  ? 362 PHE A N    1 
ATOM 5307 C CA   . PHE A 1 362 ? 103.979 102.265 96.259  1.00 49.75  ? 362 PHE A CA   1 
ATOM 5308 C C    . PHE A 1 362 ? 105.232 103.099 96.021  1.00 49.31  ? 362 PHE A C    1 
ATOM 5309 O O    . PHE A 1 362 ? 106.270 102.886 96.666  1.00 57.17  ? 362 PHE A O    1 
ATOM 5310 C CB   . PHE A 1 362 ? 103.563 101.489 95.000  1.00 50.67  ? 362 PHE A CB   1 
ATOM 5311 C CG   . PHE A 1 362 ? 104.711 100.992 94.166  1.00 48.47  ? 362 PHE A CG   1 
ATOM 5312 C CD1  . PHE A 1 362 ? 105.227 101.763 93.137  1.00 46.33  ? 362 PHE A CD1  1 
ATOM 5313 C CD2  . PHE A 1 362 ? 105.250 99.741  94.389  1.00 52.87  ? 362 PHE A CD2  1 
ATOM 5314 C CE1  . PHE A 1 362 ? 106.274 101.301 92.365  1.00 50.75  ? 362 PHE A CE1  1 
ATOM 5315 C CE2  . PHE A 1 362 ? 106.295 99.275  93.620  1.00 53.89  ? 362 PHE A CE2  1 
ATOM 5316 C CZ   . PHE A 1 362 ? 106.808 100.055 92.607  1.00 56.06  ? 362 PHE A CZ   1 
ATOM 5317 H H    . PHE A 1 362 ? 102.308 103.286 96.051  1.00 48.42  ? 362 PHE A H    1 
ATOM 5318 H HA   . PHE A 1 362 ? 104.170 101.622 96.958  1.00 51.10  ? 362 PHE A HA   1 
ATOM 5319 H HB2  . PHE A 1 362 ? 103.040 100.717 95.269  1.00 51.26  ? 362 PHE A HB2  1 
ATOM 5320 H HB3  . PHE A 1 362 ? 103.022 102.068 94.442  1.00 49.52  ? 362 PHE A HB3  1 
ATOM 5321 H HD1  . PHE A 1 362 ? 104.871 102.606 92.970  1.00 47.79  ? 362 PHE A HD1  1 
ATOM 5322 H HD2  . PHE A 1 362 ? 104.910 99.210  95.073  1.00 52.51  ? 362 PHE A HD2  1 
ATOM 5323 H HE1  . PHE A 1 362 ? 106.618 101.830 91.681  1.00 50.16  ? 362 PHE A HE1  1 
ATOM 5324 H HE2  . PHE A 1 362 ? 106.653 98.434  93.787  1.00 52.37  ? 362 PHE A HE2  1 
ATOM 5325 H HZ   . PHE A 1 362 ? 107.513 99.741  92.089  1.00 54.95  ? 362 PHE A HZ   1 
ATOM 5326 N N    . THR A 1 363 ? 105.144 104.070 95.106  1.00 44.46  ? 363 THR A N    1 
ATOM 5327 C CA   . THR A 1 363 ? 106.344 104.766 94.665  1.00 48.00  ? 363 THR A CA   1 
ATOM 5328 C C    . THR A 1 363 ? 106.968 105.597 95.777  1.00 46.04  ? 363 THR A C    1 
ATOM 5329 O O    . THR A 1 363 ? 108.197 105.587 95.931  1.00 52.69  ? 363 THR A O    1 
ATOM 5330 C CB   . THR A 1 363 ? 106.025 105.649 93.459  1.00 50.00  ? 363 THR A CB   1 
ATOM 5331 O OG1  . THR A 1 363 ? 107.244 106.112 92.867  1.00 50.30  ? 363 THR A OG1  1 
ATOM 5332 C CG2  . THR A 1 363 ? 105.191 106.844 93.872  1.00 51.06  ? 363 THR A CG2  1 
ATOM 5333 H H    . THR A 1 363 ? 104.416 104.338 94.737  1.00 46.62  ? 363 THR A H    1 
ATOM 5334 H HA   . THR A 1 363 ? 107.003 104.110 94.389  1.00 49.02  ? 363 THR A HA   1 
ATOM 5335 H HB   . THR A 1 363 ? 105.524 105.132 92.809  1.00 48.99  ? 363 THR A HB   1 
ATOM 5336 H HG1  . THR A 1 363 ? 107.074 106.636 92.232  1.00 50.32  ? 363 THR A HG1  1 
ATOM 5337 H HG21 . THR A 1 363 ? 105.758 107.511 94.290  1.00 48.98  ? 363 THR A HG21 1 
ATOM 5338 H HG22 . THR A 1 363 ? 104.765 107.235 93.094  1.00 51.05  ? 363 THR A HG22 1 
ATOM 5339 H HG23 . THR A 1 363 ? 104.508 106.569 94.502  1.00 49.25  ? 363 THR A HG23 1 
ATOM 5340 N N    . PHE A 1 364 ? 106.162 106.288 96.589  1.00 47.72  ? 364 PHE A N    1 
ATOM 5341 C CA   . PHE A 1 364 ? 106.764 107.187 97.559  1.00 54.73  ? 364 PHE A CA   1 
ATOM 5342 C C    . PHE A 1 364 ? 107.540 106.443 98.627  1.00 58.94  ? 364 PHE A C    1 
ATOM 5343 O O    . PHE A 1 364 ? 108.639 106.874 98.989  1.00 62.27  ? 364 PHE A O    1 
ATOM 5344 C CB   . PHE A 1 364 ? 105.693 108.061 98.223  1.00 59.53  ? 364 PHE A CB   1 
ATOM 5345 C CG   . PHE A 1 364 ? 106.145 108.704 99.509  1.00 61.21  ? 364 PHE A CG   1 
ATOM 5346 C CD1  . PHE A 1 364 ? 106.111 107.994 100.697 1.00 60.96  ? 364 PHE A CD1  1 
ATOM 5347 C CD2  . PHE A 1 364 ? 106.615 110.009 99.528  1.00 68.82  ? 364 PHE A CD2  1 
ATOM 5348 C CE1  . PHE A 1 364 ? 106.526 108.571 101.875 1.00 67.70  ? 364 PHE A CE1  1 
ATOM 5349 C CE2  . PHE A 1 364 ? 107.031 110.591 100.712 1.00 70.41  ? 364 PHE A CE2  1 
ATOM 5350 C CZ   . PHE A 1 364 ? 106.986 109.868 101.885 1.00 73.79  ? 364 PHE A CZ   1 
ATOM 5351 H H    . PHE A 1 364 ? 105.303 106.251 96.604  1.00 50.80  ? 364 PHE A H    1 
ATOM 5352 H HA   . PHE A 1 364 ? 107.384 107.767 97.092  1.00 54.51  ? 364 PHE A HA   1 
ATOM 5353 H HB2  . PHE A 1 364 ? 105.448 108.769 97.606  1.00 58.37  ? 364 PHE A HB2  1 
ATOM 5354 H HB3  . PHE A 1 364 ? 104.914 107.517 98.419  1.00 56.90  ? 364 PHE A HB3  1 
ATOM 5355 H HD1  . PHE A 1 364 ? 105.801 107.116 100.695 1.00 60.74  ? 364 PHE A HD1  1 
ATOM 5356 H HD2  . PHE A 1 364 ? 106.648 110.499 98.740  1.00 67.42  ? 364 PHE A HD2  1 
ATOM 5357 H HE1  . PHE A 1 364 ? 106.494 108.082 102.663 1.00 66.84  ? 364 PHE A HE1  1 
ATOM 5358 H HE2  . PHE A 1 364 ? 107.342 111.469 100.714 1.00 69.57  ? 364 PHE A HE2  1 
ATOM 5359 H HZ   . PHE A 1 364 ? 107.264 110.252 102.685 1.00 71.74  ? 364 PHE A HZ   1 
ATOM 5360 N N    . PHE A 1 365 ? 107.028 105.311 99.100  1.00 56.12  ? 365 PHE A N    1 
ATOM 5361 C CA   . PHE A 1 365 ? 107.729 104.561 100.129 1.00 59.16  ? 365 PHE A CA   1 
ATOM 5362 C C    . PHE A 1 365 ? 108.899 103.789 99.549  1.00 57.00  ? 365 PHE A C    1 
ATOM 5363 O O    . PHE A 1 365 ? 109.981 103.769 100.152 1.00 56.44  ? 365 PHE A O    1 
ATOM 5364 C CB   . PHE A 1 365 ? 106.752 103.618 100.839 1.00 59.15  ? 365 PHE A CB   1 
ATOM 5365 C CG   . PHE A 1 365 ? 106.037 104.264 101.993 1.00 64.93  ? 365 PHE A CG   1 
ATOM 5366 C CD1  . PHE A 1 365 ? 106.746 104.784 103.064 1.00 67.63  ? 365 PHE A CD1  1 
ATOM 5367 C CD2  . PHE A 1 365 ? 104.660 104.392 101.985 1.00 67.47  ? 365 PHE A CD2  1 
ATOM 5368 C CE1  . PHE A 1 365 ? 106.093 105.393 104.115 1.00 72.68  ? 365 PHE A CE1  1 
ATOM 5369 C CE2  . PHE A 1 365 ? 104.000 105.002 103.034 1.00 72.28  ? 365 PHE A CE2  1 
ATOM 5370 C CZ   . PHE A 1 365 ? 104.720 105.503 104.099 1.00 75.71  ? 365 PHE A CZ   1 
ATOM 5371 H H    . PHE A 1 365 ? 106.293 104.950 98.839  1.00 55.92  ? 365 PHE A H    1 
ATOM 5372 H HA   . PHE A 1 365 ? 108.092 105.178 100.786 1.00 60.89  ? 365 PHE A HA   1 
ATOM 5373 H HB2  . PHE A 1 365 ? 106.085 103.322 100.200 1.00 58.87  ? 365 PHE A HB2  1 
ATOM 5374 H HB3  . PHE A 1 365 ? 107.240 102.851 101.178 1.00 60.28  ? 365 PHE A HB3  1 
ATOM 5375 H HD1  . PHE A 1 365 ? 107.673 104.712 103.079 1.00 65.91  ? 365 PHE A HD1  1 
ATOM 5376 H HD2  . PHE A 1 365 ? 104.170 104.056 101.268 1.00 64.50  ? 365 PHE A HD2  1 
ATOM 5377 H HE1  . PHE A 1 365 ? 106.579 105.732 104.834 1.00 71.45  ? 365 PHE A HE1  1 
ATOM 5378 H HE2  . PHE A 1 365 ? 103.073 105.076 103.023 1.00 71.03  ? 365 PHE A HE2  1 
ATOM 5379 H HZ   . PHE A 1 365 ? 104.279 105.914 104.806 1.00 74.36  ? 365 PHE A HZ   1 
ATOM 5380 N N    . GLY A 1 366 ? 108.727 103.206 98.355  1.00 57.92  ? 366 GLY A N    1 
ATOM 5381 C CA   . GLY A 1 366 ? 109.839 102.522 97.721  1.00 57.08  ? 366 GLY A CA   1 
ATOM 5382 C C    . GLY A 1 366 ? 111.007 103.446 97.453  1.00 55.08  ? 366 GLY A C    1 
ATOM 5383 O O    . GLY A 1 366 ? 112.162 103.019 97.494  1.00 57.66  ? 366 GLY A O    1 
ATOM 5384 H H    . GLY A 1 366 ? 107.995 103.192 97.906  1.00 57.08  ? 366 GLY A H    1 
ATOM 5385 H HA2  . GLY A 1 366 ? 110.137 101.801 98.297  1.00 57.06  ? 366 GLY A HA2  1 
ATOM 5386 H HA3  . GLY A 1 366 ? 109.543 102.134 96.884  1.00 57.02  ? 366 GLY A HA3  1 
ATOM 5387 N N    . LEU A 1 367 ? 110.728 104.725 97.190  1.00 56.24  ? 367 LEU A N    1 
ATOM 5388 C CA   . LEU A 1 367 ? 111.798 105.688 96.964  1.00 56.61  ? 367 LEU A CA   1 
ATOM 5389 C C    . LEU A 1 367 ? 112.348 106.274 98.261  1.00 60.68  ? 367 LEU A C    1 
ATOM 5390 O O    . LEU A 1 367 ? 113.567 106.415 98.403  1.00 61.59  ? 367 LEU A O    1 
ATOM 5391 C CB   . LEU A 1 367 ? 111.298 106.819 96.064  1.00 58.18  ? 367 LEU A CB   1 
ATOM 5392 C CG   . LEU A 1 367 ? 111.313 106.530 94.563  1.00 63.43  ? 367 LEU A CG   1 
ATOM 5393 C CD1  . LEU A 1 367 ? 110.569 107.613 93.805  1.00 62.38  ? 367 LEU A CD1  1 
ATOM 5394 C CD2  . LEU A 1 367 ? 112.744 106.409 94.053  1.00 60.95  ? 367 LEU A CD2  1 
ATOM 5395 H H    . LEU A 1 367 ? 109.935 105.052 97.139  1.00 57.09  ? 367 LEU A H    1 
ATOM 5396 H HA   . LEU A 1 367 ? 112.526 105.240 96.507  1.00 56.85  ? 367 LEU A HA   1 
ATOM 5397 H HB2  . LEU A 1 367 ? 110.381 107.015 96.316  1.00 58.23  ? 367 LEU A HB2  1 
ATOM 5398 H HB3  . LEU A 1 367 ? 111.853 107.599 96.218  1.00 57.18  ? 367 LEU A HB3  1 
ATOM 5399 H HG   . LEU A 1 367 ? 110.863 105.686 94.400  1.00 61.46  ? 367 LEU A HG   1 
ATOM 5400 H HD11 . LEU A 1 367 ? 110.131 107.214 93.038  1.00 61.46  ? 367 LEU A HD11 1 
ATOM 5401 H HD12 . LEU A 1 367 ? 109.909 108.017 94.390  1.00 59.89  ? 367 LEU A HD12 1 
ATOM 5402 H HD13 . LEU A 1 367 ? 111.204 108.286 93.514  1.00 63.13  ? 367 LEU A HD13 1 
ATOM 5403 H HD21 . LEU A 1 367 ? 112.734 106.391 93.083  1.00 62.87  ? 367 LEU A HD21 1 
ATOM 5404 H HD22 . LEU A 1 367 ? 113.256 107.172 94.364  1.00 61.19  ? 367 LEU A HD22 1 
ATOM 5405 H HD23 . LEU A 1 367 ? 113.135 105.589 94.393  1.00 58.98  ? 367 LEU A HD23 1 
ATOM 5406 N N    . ALA A 1 368 ? 111.479 106.617 99.214  1.00 62.63  ? 368 ALA A N    1 
ATOM 5407 C CA   . ALA A 1 368 ? 111.933 107.275 100.432 1.00 61.20  ? 368 ALA A CA   1 
ATOM 5408 C C    . ALA A 1 368 ? 112.752 106.333 101.303 1.00 61.98  ? 368 ALA A C    1 
ATOM 5409 O O    . ALA A 1 368 ? 113.698 106.766 101.969 1.00 65.29  ? 368 ALA A O    1 
ATOM 5410 C CB   . ALA A 1 368 ? 110.732 107.817 101.211 1.00 58.80  ? 368 ALA A CB   1 
ATOM 5411 H H    . ALA A 1 368 ? 110.630 106.478 99.178  1.00 60.20  ? 368 ALA A H    1 
ATOM 5412 H HA   . ALA A 1 368 ? 112.493 108.030 100.194 1.00 61.90  ? 368 ALA A HA   1 
ATOM 5413 H HB1  . ALA A 1 368 ? 110.261 108.458 100.656 1.00 60.49  ? 368 ALA A HB1  1 
ATOM 5414 H HB2  . ALA A 1 368 ? 110.144 107.080 101.436 1.00 60.92  ? 368 ALA A HB2  1 
ATOM 5415 H HB3  . ALA A 1 368 ? 111.048 108.250 102.019 1.00 61.17  ? 368 ALA A HB3  1 
ATOM 5416 N N    . LEU A 1 369 ? 112.408 105.043 101.323 1.00 64.19  ? 369 LEU A N    1 
ATOM 5417 C CA   . LEU A 1 369 ? 113.099 104.144 102.241 1.00 63.65  ? 369 LEU A CA   1 
ATOM 5418 C C    . LEU A 1 369 ? 114.564 103.961 101.854 1.00 65.25  ? 369 LEU A C    1 
ATOM 5419 O O    . LEU A 1 369 ? 115.431 103.867 102.730 1.00 68.25  ? 369 LEU A O    1 
ATOM 5420 C CB   . LEU A 1 369 ? 112.380 102.799 102.308 1.00 62.66  ? 369 LEU A CB   1 
ATOM 5421 C CG   . LEU A 1 369 ? 111.317 102.742 103.411 1.00 66.84  ? 369 LEU A CG   1 
ATOM 5422 C CD1  . LEU A 1 369 ? 111.959 102.406 104.751 1.00 65.54  ? 369 LEU A CD1  1 
ATOM 5423 C CD2  . LEU A 1 369 ? 110.502 104.030 103.487 1.00 64.01  ? 369 LEU A CD2  1 
ATOM 5424 H H    . LEU A 1 369 ? 111.804 104.675 100.834 1.00 62.55  ? 369 LEU A H    1 
ATOM 5425 H HA   . LEU A 1 369 ? 113.087 104.530 103.130 1.00 62.89  ? 369 LEU A HA   1 
ATOM 5426 H HB2  . LEU A 1 369 ? 111.926 102.650 101.465 1.00 63.29  ? 369 LEU A HB2  1 
ATOM 5427 H HB3  . LEU A 1 369 ? 113.026 102.094 102.462 1.00 62.75  ? 369 LEU A HB3  1 
ATOM 5428 H HG   . LEU A 1 369 ? 110.704 102.021 103.200 1.00 66.83  ? 369 LEU A HG   1 
ATOM 5429 H HD11 . LEU A 1 369 ? 111.333 101.898 105.293 1.00 65.55  ? 369 LEU A HD11 1 
ATOM 5430 H HD12 . LEU A 1 369 ? 112.764 101.890 104.595 1.00 65.09  ? 369 LEU A HD12 1 
ATOM 5431 H HD13 . LEU A 1 369 ? 112.195 103.233 105.201 1.00 65.32  ? 369 LEU A HD13 1 
ATOM 5432 H HD21 . LEU A 1 369 ? 109.685 103.859 103.982 1.00 63.28  ? 369 LEU A HD21 1 
ATOM 5433 H HD22 . LEU A 1 369 ? 111.022 104.716 103.933 1.00 63.75  ? 369 LEU A HD22 1 
ATOM 5434 H HD23 . LEU A 1 369 ? 110.282 104.314 102.585 1.00 63.97  ? 369 LEU A HD23 1 
ATOM 5435 N N    . ASP A 1 370 ? 114.863 103.888 100.560 1.00 59.84  ? 370 ASP A N    1 
ATOM 5436 C CA   . ASP A 1 370 ? 116.244 103.772 100.083 1.00 58.09  ? 370 ASP A CA   1 
ATOM 5437 C C    . ASP A 1 370 ? 116.818 105.136 99.688  1.00 61.78  ? 370 ASP A C    1 
ATOM 5438 O O    . ASP A 1 370 ? 117.304 105.358 98.581  1.00 64.89  ? 370 ASP A O    1 
ATOM 5439 C CB   . ASP A 1 370 ? 116.319 102.747 98.947  1.00 66.49  ? 370 ASP A CB   1 
ATOM 5440 C CG   . ASP A 1 370 ? 115.740 103.250 97.623  1.00 73.30  ? 370 ASP A CG   1 
ATOM 5441 O OD1  . ASP A 1 370 ? 115.457 104.455 97.468  1.00 72.50  ? 370 ASP A OD1  1 
ATOM 5442 O OD2  . ASP A 1 370 ? 115.569 102.409 96.715  1.00 74.87  ? 370 ASP A OD2  1 
ATOM 5443 H H    . ASP A 1 370 ? 114.279 103.902 99.929  1.00 62.20  ? 370 ASP A H    1 
ATOM 5444 H HA   . ASP A 1 370 ? 116.790 103.431 100.809 1.00 61.62  ? 370 ASP A HA   1 
ATOM 5445 H HB2  . ASP A 1 370 ? 117.250 102.518 98.796  1.00 66.70  ? 370 ASP A HB2  1 
ATOM 5446 H HB3  . ASP A 1 370 ? 115.827 101.956 99.211  1.00 66.64  ? 370 ASP A HB3  1 
ATOM 5447 N N    . LEU A 1 371 ? 116.815 106.048 100.662 1.00 67.14  ? 371 LEU A N    1 
ATOM 5448 C CA   . LEU A 1 371 ? 117.229 107.424 100.405 1.00 58.97  ? 371 LEU A CA   1 
ATOM 5449 C C    . LEU A 1 371 ? 118.689 107.544 99.979  1.00 57.32  ? 371 LEU A C    1 
ATOM 5450 O O    . LEU A 1 371 ? 119.061 108.561 99.384  1.00 57.38  ? 371 LEU A O    1 
ATOM 5451 C CB   . LEU A 1 371 ? 116.987 108.280 101.651 1.00 55.18  ? 371 LEU A CB   1 
ATOM 5452 C CG   . LEU A 1 371 ? 116.226 109.600 101.482 1.00 58.63  ? 371 LEU A CG   1 
ATOM 5453 C CD1  . LEU A 1 371 ? 114.857 109.418 100.836 1.00 62.57  ? 371 LEU A CD1  1 
ATOM 5454 C CD2  . LEU A 1 371 ? 116.080 110.277 102.833 1.00 59.34  ? 371 LEU A CD2  1 
ATOM 5455 H H    . LEU A 1 371 ? 116.581 105.892 101.474 1.00 64.73  ? 371 LEU A H    1 
ATOM 5456 H HA   . LEU A 1 371 ? 116.692 107.777 99.681  1.00 59.21  ? 371 LEU A HA   1 
ATOM 5457 H HB2  . LEU A 1 371 ? 116.486 107.748 102.289 1.00 58.60  ? 371 LEU A HB2  1 
ATOM 5458 H HB3  . LEU A 1 371 ? 117.851 108.499 102.035 1.00 57.14  ? 371 LEU A HB3  1 
ATOM 5459 H HG   . LEU A 1 371 ? 116.746 110.188 100.912 1.00 60.11  ? 371 LEU A HG   1 
ATOM 5460 H HD11 . LEU A 1 371 ? 114.471 110.292 100.673 1.00 61.72  ? 371 LEU A HD11 1 
ATOM 5461 H HD12 . LEU A 1 371 ? 114.952 108.942 99.998  1.00 62.83  ? 371 LEU A HD12 1 
ATOM 5462 H HD13 . LEU A 1 371 ? 114.290 108.918 101.440 1.00 61.86  ? 371 LEU A HD13 1 
ATOM 5463 H HD21 . LEU A 1 371 ? 115.581 111.101 102.721 1.00 61.82  ? 371 LEU A HD21 1 
ATOM 5464 H HD22 . LEU A 1 371 ? 115.604 109.683 103.435 1.00 60.18  ? 371 LEU A HD22 1 
ATOM 5465 H HD23 . LEU A 1 371 ? 116.962 110.469 103.188 1.00 58.83  ? 371 LEU A HD23 1 
ATOM 5466 N N    . GLN A 1 372 ? 119.529 106.546 100.268 1.00 63.53  ? 372 GLN A N    1 
ATOM 5467 C CA   . GLN A 1 372 ? 120.944 106.658 99.921  1.00 62.60  ? 372 GLN A CA   1 
ATOM 5468 C C    . GLN A 1 372 ? 121.143 106.723 98.411  1.00 67.59  ? 372 GLN A C    1 
ATOM 5469 O O    . GLN A 1 372 ? 121.914 107.550 97.911  1.00 71.42  ? 372 GLN A O    1 
ATOM 5470 C CB   . GLN A 1 372 ? 121.729 105.484 100.509 1.00 65.73  ? 372 GLN A CB   1 
ATOM 5471 C CG   . GLN A 1 372 ? 123.176 105.818 100.847 1.00 69.52  ? 372 GLN A CG   1 
ATOM 5472 C CD   . GLN A 1 372 ? 124.012 106.123 99.616  1.00 70.17  ? 372 GLN A CD   1 
ATOM 5473 O OE1  . GLN A 1 372 ? 124.390 105.220 98.870  1.00 67.96  ? 372 GLN A OE1  1 
ATOM 5474 N NE2  . GLN A 1 372 ? 124.306 107.400 99.400  1.00 69.38  ? 372 GLN A NE2  1 
ATOM 5475 H H    . GLN A 1 372 ? 119.310 105.811 100.656 1.00 63.88  ? 372 GLN A H    1 
ATOM 5476 H HA   . GLN A 1 372 ? 121.299 107.475 100.304 1.00 63.95  ? 372 GLN A HA   1 
ATOM 5477 H HB2  . GLN A 1 372 ? 121.294 105.193 101.325 1.00 66.50  ? 372 GLN A HB2  1 
ATOM 5478 H HB3  . GLN A 1 372 ? 121.737 104.759 99.864  1.00 66.23  ? 372 GLN A HB3  1 
ATOM 5479 H HG2  . GLN A 1 372 ? 123.195 106.600 101.421 1.00 70.31  ? 372 GLN A HG2  1 
ATOM 5480 H HG3  . GLN A 1 372 ? 123.579 105.061 101.301 1.00 67.58  ? 372 GLN A HG3  1 
ATOM 5481 H HE21 . GLN A 1 372 ? 124.025 108.005 99.943  1.00 69.58  ? 372 GLN A HE21 1 
ATOM 5482 H HE22 . GLN A 1 372 ? 124.777 107.623 98.715  1.00 68.20  ? 372 GLN A HE22 1 
ATOM 5483 N N    . ALA A 1 373 ? 120.455 105.856 97.666  1.00 68.52  ? 373 ALA A N    1 
ATOM 5484 C CA   . ALA A 1 373 ? 120.665 105.785 96.225  1.00 66.18  ? 373 ALA A CA   1 
ATOM 5485 C C    . ALA A 1 373 ? 120.250 107.064 95.511  1.00 70.36  ? 373 ALA A C    1 
ATOM 5486 O O    . ALA A 1 373 ? 120.696 107.302 94.384  1.00 73.81  ? 373 ALA A O    1 
ATOM 5487 C CB   . ALA A 1 373 ? 119.897 104.600 95.641  1.00 68.18  ? 373 ALA A CB   1 
ATOM 5488 H H    . ALA A 1 373 ? 119.869 105.304 97.969  1.00 66.86  ? 373 ALA A H    1 
ATOM 5489 H HA   . ALA A 1 373 ? 121.609 105.642 96.053  1.00 66.70  ? 373 ALA A HA   1 
ATOM 5490 H HB1  . ALA A 1 373 ? 120.217 103.782 96.055  1.00 69.56  ? 373 ALA A HB1  1 
ATOM 5491 H HB2  . ALA A 1 373 ? 118.951 104.716 95.825  1.00 66.99  ? 373 ALA A HB2  1 
ATOM 5492 H HB3  . ALA A 1 373 ? 120.047 104.567 94.684  1.00 69.81  ? 373 ALA A HB3  1 
ATOM 5493 N N    . LEU A 1 374 ? 119.410 107.888 96.137  1.00 66.39  ? 374 LEU A N    1 
ATOM 5494 C CA   . LEU A 1 374 ? 118.910 109.088 95.478  1.00 58.46  ? 374 LEU A CA   1 
ATOM 5495 C C    . LEU A 1 374 ? 119.970 110.183 95.409  1.00 57.49  ? 374 LEU A C    1 
ATOM 5496 O O    . LEU A 1 374 ? 120.102 110.851 94.378  1.00 55.85  ? 374 LEU A O    1 
ATOM 5497 C CB   . LEU A 1 374 ? 117.663 109.588 96.206  1.00 60.29  ? 374 LEU A CB   1 
ATOM 5498 C CG   . LEU A 1 374 ? 116.343 109.114 95.597  1.00 65.67  ? 374 LEU A CG   1 
ATOM 5499 C CD1  . LEU A 1 374 ? 116.250 107.602 95.650  1.00 69.10  ? 374 LEU A CD1  1 
ATOM 5500 C CD2  . LEU A 1 374 ? 115.167 109.731 96.329  1.00 64.36  ? 374 LEU A CD2  1 
ATOM 5501 H H    . LEU A 1 374 ? 119.118 107.773 96.938  1.00 65.59  ? 374 LEU A H    1 
ATOM 5502 H HA   . LEU A 1 374 ? 118.655 108.863 94.570  1.00 61.85  ? 374 LEU A HA   1 
ATOM 5503 H HB2  . LEU A 1 374 ? 117.691 109.280 97.124  1.00 61.86  ? 374 LEU A HB2  1 
ATOM 5504 H HB3  . LEU A 1 374 ? 117.663 110.558 96.187  1.00 62.22  ? 374 LEU A HB3  1 
ATOM 5505 H HG   . LEU A 1 374 ? 116.302 109.390 94.667  1.00 65.40  ? 374 LEU A HG   1 
ATOM 5506 H HD11 . LEU A 1 374 ? 115.387 107.327 95.302  1.00 67.83  ? 374 LEU A HD11 1 
ATOM 5507 H HD12 . LEU A 1 374 ? 116.960 107.221 95.109  1.00 67.54  ? 374 LEU A HD12 1 
ATOM 5508 H HD13 . LEU A 1 374 ? 116.344 107.312 96.571  1.00 65.93  ? 374 LEU A HD13 1 
ATOM 5509 H HD21 . LEU A 1 374 ? 114.345 109.453 95.895  1.00 64.03  ? 374 LEU A HD21 1 
ATOM 5510 H HD22 . LEU A 1 374 ? 115.175 109.426 97.249  1.00 64.37  ? 374 LEU A HD22 1 
ATOM 5511 H HD23 . LEU A 1 374 ? 115.245 110.695 96.301  1.00 63.79  ? 374 LEU A HD23 1 
ATOM 5512 N N    . GLY A 1 375 ? 120.730 110.381 96.484  1.00 61.15  ? 375 GLY A N    1 
ATOM 5513 C CA   . GLY A 1 375 ? 121.718 111.443 96.523  1.00 63.14  ? 375 GLY A CA   1 
ATOM 5514 C C    . GLY A 1 375 ? 123.050 111.021 97.107  1.00 69.15  ? 375 GLY A C    1 
ATOM 5515 O O    . GLY A 1 375 ? 123.397 109.837 97.088  1.00 74.91  ? 375 GLY A O    1 
ATOM 5516 H H    . GLY A 1 375 ? 120.689 109.911 97.203  1.00 63.06  ? 375 GLY A H    1 
ATOM 5517 H HA2  . GLY A 1 375 ? 121.878 111.768 95.623  1.00 64.41  ? 375 GLY A HA2  1 
ATOM 5518 H HA3  . GLY A 1 375 ? 121.377 112.180 97.052  1.00 63.57  ? 375 GLY A HA3  1 
ATOM 5519 N N    . SER A 1 376 ? 123.808 111.987 97.627  1.00 72.67  ? 376 SER A N    1 
ATOM 5520 C CA   . SER A 1 376 ? 125.135 111.717 98.172  1.00 74.13  ? 376 SER A CA   1 
ATOM 5521 C C    . SER A 1 376 ? 125.089 111.479 99.680  1.00 69.63  ? 376 SER A C    1 
ATOM 5522 O O    . SER A 1 376 ? 125.482 110.409 100.157 1.00 73.12  ? 376 SER A O    1 
ATOM 5523 C CB   . SER A 1 376 ? 126.081 112.878 97.843  1.00 76.31  ? 376 SER A CB   1 
ATOM 5524 O OG   . SER A 1 376 ? 125.536 114.116 98.265  1.00 78.78  ? 376 SER A OG   1 
ATOM 5525 H H    . SER A 1 376 ? 123.574 112.813 97.675  1.00 72.73  ? 376 SER A H    1 
ATOM 5526 H HA   . SER A 1 376 ? 125.491 110.917 97.755  1.00 73.91  ? 376 SER A HA   1 
ATOM 5527 H HB2  . SER A 1 376 ? 126.926 112.734 98.296  1.00 75.43  ? 376 SER A HB2  1 
ATOM 5528 H HB3  . SER A 1 376 ? 126.221 112.907 96.884  1.00 75.33  ? 376 SER A HB3  1 
ATOM 5529 H HG   . SER A 1 376 ? 126.073 114.739 98.096  1.00 77.66  ? 376 SER A HG   1 
ATOM 5530 N N    . ASN A 1 377 ? 124.613 112.464 100.440 1.00 61.98  ? 377 ASN A N    1 
ATOM 5531 C CA   . ASN A 1 377 ? 124.546 112.376 101.892 1.00 59.97  ? 377 ASN A CA   1 
ATOM 5532 C C    . ASN A 1 377 ? 123.090 112.388 102.335 1.00 54.69  ? 377 ASN A C    1 
ATOM 5533 O O    . ASN A 1 377 ? 122.278 113.163 101.822 1.00 57.14  ? 377 ASN A O    1 
ATOM 5534 C CB   . ASN A 1 377 ? 125.347 113.518 102.553 1.00 54.50  ? 377 ASN A CB   1 
ATOM 5535 C CG   . ASN A 1 377 ? 124.557 114.808 102.692 1.00 55.77  ? 377 ASN A CG   1 
ATOM 5536 O OD1  . ASN A 1 377 ? 123.486 114.842 103.297 1.00 50.16  ? 377 ASN A OD1  1 
ATOM 5537 N ND2  . ASN A 1 377 ? 125.095 115.886 102.131 1.00 61.17  ? 377 ASN A ND2  1 
ATOM 5538 H H    . ASN A 1 377 ? 124.317 113.208 100.126 1.00 63.61  ? 377 ASN A H    1 
ATOM 5539 H HA   . ASN A 1 377 ? 124.937 111.537 102.179 1.00 63.24  ? 377 ASN A HA   1 
ATOM 5540 H HB2  . ASN A 1 377 ? 125.616 113.239 103.442 1.00 54.75  ? 377 ASN A HB2  1 
ATOM 5541 H HB3  . ASN A 1 377 ? 126.132 113.704 102.014 1.00 58.25  ? 377 ASN A HB3  1 
ATOM 5542 H HD21 . ASN A 1 377 ? 125.846 115.825 101.717 1.00 61.26  ? 377 ASN A HD21 1 
ATOM 5543 H HD22 . ASN A 1 377 ? 124.692 116.644 102.179 1.00 62.05  ? 377 ASN A HD22 1 
ATOM 5544 N N    . ILE A 1 378 ? 122.768 111.509 103.286 1.00 53.63  ? 378 ILE A N    1 
ATOM 5545 C CA   . ILE A 1 378 ? 121.378 111.304 103.680 1.00 53.45  ? 378 ILE A CA   1 
ATOM 5546 C C    . ILE A 1 378 ? 120.841 112.514 104.437 1.00 56.89  ? 378 ILE A C    1 
ATOM 5547 O O    . ILE A 1 378 ? 119.676 112.894 104.275 1.00 55.16  ? 378 ILE A O    1 
ATOM 5548 C CB   . ILE A 1 378 ? 121.250 110.018 104.515 1.00 50.32  ? 378 ILE A CB   1 
ATOM 5549 C CG1  . ILE A 1 378 ? 121.696 108.798 103.707 1.00 53.83  ? 378 ILE A CG1  1 
ATOM 5550 C CG2  . ILE A 1 378 ? 119.816 109.827 104.972 1.00 53.72  ? 378 ILE A CG2  1 
ATOM 5551 C CD1  . ILE A 1 378 ? 122.195 107.655 104.567 1.00 60.38  ? 378 ILE A CD1  1 
ATOM 5552 H H    . ILE A 1 378 ? 123.333 111.021 103.713 1.00 55.43  ? 378 ILE A H    1 
ATOM 5553 H HA   . ILE A 1 378 ? 120.840 111.192 102.881 1.00 54.16  ? 378 ILE A HA   1 
ATOM 5554 H HB   . ILE A 1 378 ? 121.818 110.097 105.298 1.00 53.66  ? 378 ILE A HB   1 
ATOM 5555 H HG12 . ILE A 1 378 ? 120.943 108.473 103.190 1.00 56.46  ? 378 ILE A HG12 1 
ATOM 5556 H HG13 . ILE A 1 378 ? 122.417 109.054 103.112 1.00 57.61  ? 378 ILE A HG13 1 
ATOM 5557 H HG21 . ILE A 1 378 ? 119.722 108.939 105.351 1.00 55.42  ? 378 ILE A HG21 1 
ATOM 5558 H HG22 . ILE A 1 378 ? 119.606 110.495 105.640 1.00 55.15  ? 378 ILE A HG22 1 
ATOM 5559 H HG23 . ILE A 1 378 ? 119.227 109.924 104.208 1.00 55.10  ? 378 ILE A HG23 1 
ATOM 5560 H HD11 . ILE A 1 378 ? 122.348 106.880 104.005 1.00 61.17  ? 378 ILE A HD11 1 
ATOM 5561 H HD12 . ILE A 1 378 ? 123.024 107.921 104.996 1.00 60.14  ? 378 ILE A HD12 1 
ATOM 5562 H HD13 . ILE A 1 378 ? 121.526 107.449 105.239 1.00 58.13  ? 378 ILE A HD13 1 
ATOM 5563 N N    . PHE A 1 379 ? 121.665 113.120 105.294 1.00 53.74  ? 379 PHE A N    1 
ATOM 5564 C CA   . PHE A 1 379 ? 121.171 114.173 106.178 1.00 52.13  ? 379 PHE A CA   1 
ATOM 5565 C C    . PHE A 1 379 ? 120.628 115.354 105.382 1.00 47.74  ? 379 PHE A C    1 
ATOM 5566 O O    . PHE A 1 379 ? 119.540 115.869 105.672 1.00 50.08  ? 379 PHE A O    1 
ATOM 5567 C CB   . PHE A 1 379 ? 122.286 114.633 107.118 1.00 50.87  ? 379 PHE A CB   1 
ATOM 5568 C CG   . PHE A 1 379 ? 122.966 113.511 107.847 1.00 48.04  ? 379 PHE A CG   1 
ATOM 5569 C CD1  . PHE A 1 379 ? 122.252 112.689 108.701 1.00 51.94  ? 379 PHE A CD1  1 
ATOM 5570 C CD2  . PHE A 1 379 ? 124.319 113.280 107.679 1.00 43.67  ? 379 PHE A CD2  1 
ATOM 5571 C CE1  . PHE A 1 379 ? 122.876 111.658 109.372 1.00 57.37  ? 379 PHE A CE1  1 
ATOM 5572 C CE2  . PHE A 1 379 ? 124.948 112.250 108.348 1.00 50.82  ? 379 PHE A CE2  1 
ATOM 5573 C CZ   . PHE A 1 379 ? 124.226 111.438 109.195 1.00 58.46  ? 379 PHE A CZ   1 
ATOM 5574 H H    . PHE A 1 379 ? 122.502 112.944 105.378 1.00 52.88  ? 379 PHE A H    1 
ATOM 5575 H HA   . PHE A 1 379 ? 120.449 113.819 106.720 1.00 52.97  ? 379 PHE A HA   1 
ATOM 5576 H HB2  . PHE A 1 379 ? 122.960 115.100 106.599 1.00 51.41  ? 379 PHE A HB2  1 
ATOM 5577 H HB3  . PHE A 1 379 ? 121.909 115.232 107.781 1.00 50.84  ? 379 PHE A HB3  1 
ATOM 5578 H HD1  . PHE A 1 379 ? 121.342 112.834 108.823 1.00 51.10  ? 379 PHE A HD1  1 
ATOM 5579 H HD2  . PHE A 1 379 ? 124.811 113.825 107.109 1.00 47.34  ? 379 PHE A HD2  1 
ATOM 5580 H HE1  . PHE A 1 379 ? 122.387 111.111 109.943 1.00 54.43  ? 379 PHE A HE1  1 
ATOM 5581 H HE2  . PHE A 1 379 ? 125.858 112.105 108.227 1.00 51.14  ? 379 PHE A HE2  1 
ATOM 5582 H HZ   . PHE A 1 379 ? 124.648 110.744 109.647 1.00 55.43  ? 379 PHE A HZ   1 
ATOM 5583 N N    . LEU A 1 380 ? 121.380 115.805 104.377 1.00 41.90  ? 380 LEU A N    1 
ATOM 5584 C CA   . LEU A 1 380 ? 120.934 116.943 103.584 1.00 40.58  ? 380 LEU A CA   1 
ATOM 5585 C C    . LEU A 1 380 ? 119.665 116.610 102.814 1.00 41.30  ? 380 LEU A C    1 
ATOM 5586 O O    . LEU A 1 380 ? 118.763 117.447 102.704 1.00 45.62  ? 380 LEU A O    1 
ATOM 5587 C CB   . LEU A 1 380 ? 122.044 117.386 102.631 1.00 39.58  ? 380 LEU A CB   1 
ATOM 5588 C CG   . LEU A 1 380 ? 121.822 118.707 101.888 1.00 39.97  ? 380 LEU A CG   1 
ATOM 5589 C CD1  . LEU A 1 380 ? 121.368 119.810 102.834 1.00 37.17  ? 380 LEU A CD1  1 
ATOM 5590 C CD2  . LEU A 1 380 ? 123.086 119.121 101.154 1.00 46.42  ? 380 LEU A CD2  1 
ATOM 5591 H H    . LEU A 1 380 ? 122.138 115.475 104.141 1.00 46.16  ? 380 LEU A H    1 
ATOM 5592 H HA   . LEU A 1 380 ? 120.735 117.676 104.187 1.00 42.98  ? 380 LEU A HA   1 
ATOM 5593 H HB2  . LEU A 1 380 ? 122.863 117.479 103.142 1.00 42.90  ? 380 LEU A HB2  1 
ATOM 5594 H HB3  . LEU A 1 380 ? 122.161 116.696 101.960 1.00 44.65  ? 380 LEU A HB3  1 
ATOM 5595 H HG   . LEU A 1 380 ? 121.124 118.579 101.227 1.00 42.10  ? 380 LEU A HG   1 
ATOM 5596 H HD11 . LEU A 1 380 ? 121.437 120.664 102.377 1.00 38.85  ? 380 LEU A HD11 1 
ATOM 5597 H HD12 . LEU A 1 380 ? 120.447 119.648 103.092 1.00 39.12  ? 380 LEU A HD12 1 
ATOM 5598 H HD13 . LEU A 1 380 ? 121.939 119.809 103.618 1.00 39.85  ? 380 LEU A HD13 1 
ATOM 5599 H HD21 . LEU A 1 380 ? 123.329 118.423 100.526 1.00 45.86  ? 380 LEU A HD21 1 
ATOM 5600 H HD22 . LEU A 1 380 ? 122.917 119.949 100.678 1.00 45.74  ? 380 LEU A HD22 1 
ATOM 5601 H HD23 . LEU A 1 380 ? 123.798 119.250 101.799 1.00 45.84  ? 380 LEU A HD23 1 
ATOM 5602 N N    . LEU A 1 381 ? 119.574 115.393 102.272 1.00 42.31  ? 381 LEU A N    1 
ATOM 5603 C CA   . LEU A 1 381 ? 118.361 114.995 101.567 1.00 40.16  ? 381 LEU A CA   1 
ATOM 5604 C C    . LEU A 1 381 ? 117.157 115.003 102.498 1.00 44.05  ? 381 LEU A C    1 
ATOM 5605 O O    . LEU A 1 381 ? 116.078 115.472 102.123 1.00 47.82  ? 381 LEU A O    1 
ATOM 5606 C CB   . LEU A 1 381 ? 118.538 113.610 100.946 1.00 41.85  ? 381 LEU A CB   1 
ATOM 5607 C CG   . LEU A 1 381 ? 119.093 113.556 99.523  1.00 45.67  ? 381 LEU A CG   1 
ATOM 5608 C CD1  . LEU A 1 381 ? 119.369 112.119 99.126  1.00 56.24  ? 381 LEU A CD1  1 
ATOM 5609 C CD2  . LEU A 1 381 ? 118.130 114.204 98.543  1.00 45.99  ? 381 LEU A CD2  1 
ATOM 5610 H H    . LEU A 1 381 ? 120.190 114.793 102.300 1.00 46.26  ? 381 LEU A H    1 
ATOM 5611 H HA   . LEU A 1 381 ? 118.190 115.630 100.855 1.00 42.36  ? 381 LEU A HA   1 
ATOM 5612 H HB2  . LEU A 1 381 ? 119.144 113.102 101.508 1.00 46.22  ? 381 LEU A HB2  1 
ATOM 5613 H HB3  . LEU A 1 381 ? 117.673 113.172 100.932 1.00 45.23  ? 381 LEU A HB3  1 
ATOM 5614 H HG   . LEU A 1 381 ? 119.930 114.044 99.490  1.00 46.99  ? 381 LEU A HG   1 
ATOM 5615 H HD11 . LEU A 1 381 ? 119.469 112.071 98.163  1.00 57.99  ? 381 LEU A HD11 1 
ATOM 5616 H HD12 . LEU A 1 381 ? 120.184 111.822 99.560  1.00 55.96  ? 381 LEU A HD12 1 
ATOM 5617 H HD13 . LEU A 1 381 ? 118.623 111.566 99.407  1.00 54.81  ? 381 LEU A HD13 1 
ATOM 5618 H HD21 . LEU A 1 381 ? 118.120 115.162 98.692  1.00 46.21  ? 381 LEU A HD21 1 
ATOM 5619 H HD22 . LEU A 1 381 ? 118.426 114.016 97.638  1.00 48.69  ? 381 LEU A HD22 1 
ATOM 5620 H HD23 . LEU A 1 381 ? 117.243 113.837 98.682  1.00 46.13  ? 381 LEU A HD23 1 
ATOM 5621 N N    . GLN A 1 382 ? 117.321 114.486 103.716 1.00 44.17  ? 382 GLN A N    1 
ATOM 5622 C CA   . GLN A 1 382 ? 116.217 114.478 104.670 1.00 46.40  ? 382 GLN A CA   1 
ATOM 5623 C C    . GLN A 1 382 ? 115.791 115.898 105.023 1.00 41.95  ? 382 GLN A C    1 
ATOM 5624 O O    . GLN A 1 382 ? 114.593 116.219 105.039 1.00 46.79  ? 382 GLN A O    1 
ATOM 5625 C CB   . GLN A 1 382 ? 116.628 113.710 105.926 1.00 49.84  ? 382 GLN A CB   1 
ATOM 5626 C CG   . GLN A 1 382 ? 116.319 112.225 105.873 1.00 51.24  ? 382 GLN A CG   1 
ATOM 5627 C CD   . GLN A 1 382 ? 115.008 111.873 106.546 1.00 59.43  ? 382 GLN A CD   1 
ATOM 5628 O OE1  . GLN A 1 382 ? 114.138 111.245 105.945 1.00 66.25  ? 382 GLN A OE1  1 
ATOM 5629 N NE2  . GLN A 1 382 ? 114.867 112.264 107.807 1.00 58.28  ? 382 GLN A NE2  1 
ATOM 5630 H H    . GLN A 1 382 ? 118.052 114.140 104.009 1.00 46.70  ? 382 GLN A H    1 
ATOM 5631 H HA   . GLN A 1 382 ? 115.457 114.024 104.274 1.00 48.71  ? 382 GLN A HA   1 
ATOM 5632 H HB2  . GLN A 1 382 ? 117.584 113.809 106.055 1.00 51.22  ? 382 GLN A HB2  1 
ATOM 5633 H HB3  . GLN A 1 382 ? 116.156 114.087 106.684 1.00 49.47  ? 382 GLN A HB3  1 
ATOM 5634 H HG2  . GLN A 1 382 ? 116.263 111.948 104.946 1.00 52.35  ? 382 GLN A HG2  1 
ATOM 5635 H HG3  . GLN A 1 382 ? 117.027 111.738 106.321 1.00 50.90  ? 382 GLN A HG3  1 
ATOM 5636 H HE21 . GLN A 1 382 ? 115.499 112.699 108.196 1.00 56.47  ? 382 GLN A HE21 1 
ATOM 5637 H HE22 . GLN A 1 382 ? 114.142 112.085 108.232 1.00 60.01  ? 382 GLN A HE22 1 
ATOM 5638 N N    . VAL A 1 383 ? 116.764 116.768 105.300 1.00 37.18  ? 383 VAL A N    1 
ATOM 5639 C CA   . VAL A 1 383 ? 116.442 118.147 105.659 1.00 36.38  ? 383 VAL A CA   1 
ATOM 5640 C C    . VAL A 1 383 ? 115.713 118.834 104.514 1.00 41.70  ? 383 VAL A C    1 
ATOM 5641 O O    . VAL A 1 383 ? 114.717 119.537 104.724 1.00 43.54  ? 383 VAL A O    1 
ATOM 5642 C CB   . VAL A 1 383 ? 117.719 118.913 106.050 1.00 36.52  ? 383 VAL A CB   1 
ATOM 5643 C CG1  . VAL A 1 383 ? 117.444 120.410 106.112 1.00 40.36  ? 383 VAL A CG1  1 
ATOM 5644 C CG2  . VAL A 1 383 ? 118.257 118.408 107.375 1.00 40.64  ? 383 VAL A CG2  1 
ATOM 5645 H H    . VAL A 1 383 ? 117.605 116.588 105.287 1.00 41.57  ? 383 VAL A H    1 
ATOM 5646 H HA   . VAL A 1 383 ? 115.851 118.141 106.428 1.00 39.72  ? 383 VAL A HA   1 
ATOM 5647 H HB   . VAL A 1 383 ? 118.398 118.761 105.373 1.00 39.78  ? 383 VAL A HB   1 
ATOM 5648 H HG11 . VAL A 1 383 ? 116.525 120.555 106.386 1.00 41.26  ? 383 VAL A HG11 1 
ATOM 5649 H HG12 . VAL A 1 383 ? 118.046 120.814 106.756 1.00 40.97  ? 383 VAL A HG12 1 
ATOM 5650 H HG13 . VAL A 1 383 ? 117.597 120.795 105.235 1.00 39.51  ? 383 VAL A HG13 1 
ATOM 5651 H HG21 . VAL A 1 383 ? 118.983 118.983 107.663 1.00 41.21  ? 383 VAL A HG21 1 
ATOM 5652 H HG22 . VAL A 1 383 ? 117.543 118.421 108.032 1.00 42.01  ? 383 VAL A HG22 1 
ATOM 5653 H HG23 . VAL A 1 383 ? 118.581 117.503 107.255 1.00 43.13  ? 383 VAL A HG23 1 
ATOM 5654 N N    . LEU A 1 384 ? 116.198 118.647 103.284 1.00 42.30  ? 384 LEU A N    1 
ATOM 5655 C CA   . LEU A 1 384 ? 115.588 119.319 102.144 1.00 33.42  ? 384 LEU A CA   1 
ATOM 5656 C C    . LEU A 1 384 ? 114.200 118.766 101.853 1.00 37.71  ? 384 LEU A C    1 
ATOM 5657 O O    . LEU A 1 384 ? 113.300 119.520 101.474 1.00 40.86  ? 384 LEU A O    1 
ATOM 5658 C CB   . LEU A 1 384 ? 116.491 119.194 100.917 1.00 32.48  ? 384 LEU A CB   1 
ATOM 5659 C CG   . LEU A 1 384 ? 117.734 120.090 100.908 1.00 35.36  ? 384 LEU A CG   1 
ATOM 5660 C CD1  . LEU A 1 384 ? 118.479 119.953 99.592  1.00 43.66  ? 384 LEU A CD1  1 
ATOM 5661 C CD2  . LEU A 1 384 ? 117.376 121.549 101.164 1.00 34.74  ? 384 LEU A CD2  1 
ATOM 5662 H H    . LEU A 1 384 ? 116.867 118.143 103.089 1.00 41.79  ? 384 LEU A H    1 
ATOM 5663 H HA   . LEU A 1 384 ? 115.483 120.258 102.357 1.00 35.39  ? 384 LEU A HA   1 
ATOM 5664 H HB2  . LEU A 1 384 ? 116.797 118.275 100.855 1.00 36.36  ? 384 LEU A HB2  1 
ATOM 5665 H HB3  . LEU A 1 384 ? 115.969 119.414 100.130 1.00 36.05  ? 384 LEU A HB3  1 
ATOM 5666 H HG   . LEU A 1 384 ? 118.330 119.804 101.617 1.00 38.05  ? 384 LEU A HG   1 
ATOM 5667 H HD11 . LEU A 1 384 ? 117.895 120.230 98.868  1.00 42.44  ? 384 LEU A HD11 1 
ATOM 5668 H HD12 . LEU A 1 384 ? 119.267 120.518 99.616  1.00 40.56  ? 384 LEU A HD12 1 
ATOM 5669 H HD13 . LEU A 1 384 ? 118.739 119.026 99.471  1.00 42.16  ? 384 LEU A HD13 1 
ATOM 5670 H HD21 . LEU A 1 384 ? 117.205 121.671 102.111 1.00 35.08  ? 384 LEU A HD21 1 
ATOM 5671 H HD22 . LEU A 1 384 ? 118.118 122.108 100.888 1.00 36.38  ? 384 LEU A HD22 1 
ATOM 5672 H HD23 . LEU A 1 384 ? 116.584 121.774 100.651 1.00 36.74  ? 384 LEU A HD23 1 
ATOM 5673 N N    . ILE A 1 385 ? 113.997 117.459 102.030 1.00 37.62  ? 385 ILE A N    1 
ATOM 5674 C CA   . ILE A 1 385 ? 112.659 116.897 101.870 1.00 39.55  ? 385 ILE A CA   1 
ATOM 5675 C C    . ILE A 1 385 ? 111.707 117.533 102.871 1.00 43.09  ? 385 ILE A C    1 
ATOM 5676 O O    . ILE A 1 385 ? 110.607 117.979 102.519 1.00 46.29  ? 385 ILE A O    1 
ATOM 5677 C CB   . ILE A 1 385 ? 112.695 115.365 102.026 1.00 41.05  ? 385 ILE A CB   1 
ATOM 5678 C CG1  . ILE A 1 385 ? 113.348 114.718 100.802 1.00 48.87  ? 385 ILE A CG1  1 
ATOM 5679 C CG2  . ILE A 1 385 ? 111.287 114.820 102.240 1.00 43.65  ? 385 ILE A CG2  1 
ATOM 5680 C CD1  . ILE A 1 385 ? 113.646 113.242 100.976 1.00 50.88  ? 385 ILE A CD1  1 
ATOM 5681 H H    . ILE A 1 385 ? 114.605 116.888 102.240 1.00 39.95  ? 385 ILE A H    1 
ATOM 5682 H HA   . ILE A 1 385 ? 112.337 117.100 100.978 1.00 40.95  ? 385 ILE A HA   1 
ATOM 5683 H HB   . ILE A 1 385 ? 113.228 115.150 102.807 1.00 43.61  ? 385 ILE A HB   1 
ATOM 5684 H HG12 . ILE A 1 385 ? 112.749 114.811 100.045 1.00 47.59  ? 385 ILE A HG12 1 
ATOM 5685 H HG13 . ILE A 1 385 ? 114.185 115.171 100.616 1.00 45.93  ? 385 ILE A HG13 1 
ATOM 5686 H HG21 . ILE A 1 385 ? 110.680 115.264 101.626 1.00 44.16  ? 385 ILE A HG21 1 
ATOM 5687 H HG22 . ILE A 1 385 ? 111.283 113.865 102.073 1.00 46.84  ? 385 ILE A HG22 1 
ATOM 5688 H HG23 . ILE A 1 385 ? 111.015 114.991 103.155 1.00 44.69  ? 385 ILE A HG23 1 
ATOM 5689 H HD11 . ILE A 1 385 ? 114.047 113.101 101.848 1.00 49.07  ? 385 ILE A HD11 1 
ATOM 5690 H HD12 . ILE A 1 385 ? 112.819 112.741 100.907 1.00 50.10  ? 385 ILE A HD12 1 
ATOM 5691 H HD13 . ILE A 1 385 ? 114.259 112.960 100.279 1.00 49.60  ? 385 ILE A HD13 1 
ATOM 5692 N N    . GLY A 1 386 ? 112.124 117.592 104.138 1.00 43.07  ? 386 GLY A N    1 
ATOM 5693 C CA   . GLY A 1 386 ? 111.271 118.188 105.152 1.00 41.50  ? 386 GLY A CA   1 
ATOM 5694 C C    . GLY A 1 386 ? 110.957 119.642 104.862 1.00 38.61  ? 386 GLY A C    1 
ATOM 5695 O O    . GLY A 1 386 ? 109.824 120.093 105.049 1.00 44.50  ? 386 GLY A O    1 
ATOM 5696 H H    . GLY A 1 386 ? 112.880 117.302 104.426 1.00 43.45  ? 386 GLY A H    1 
ATOM 5697 H HA2  . GLY A 1 386 ? 110.436 117.696 105.201 1.00 44.78  ? 386 GLY A HA2  1 
ATOM 5698 H HA3  . GLY A 1 386 ? 111.710 118.134 106.015 1.00 43.72  ? 386 GLY A HA3  1 
ATOM 5699 N N    . VAL A 1 387 ? 111.955 120.396 104.400 1.00 34.36  ? 387 VAL A N    1 
ATOM 5700 C CA   . VAL A 1 387 ? 111.752 121.818 104.142 1.00 37.41  ? 387 VAL A CA   1 
ATOM 5701 C C    . VAL A 1 387 ? 110.853 122.027 102.929 1.00 46.01  ? 387 VAL A C    1 
ATOM 5702 O O    . VAL A 1 387 ? 109.986 122.908 102.931 1.00 50.39  ? 387 VAL A O    1 
ATOM 5703 C CB   . VAL A 1 387 ? 113.111 122.521 103.971 1.00 39.03  ? 387 VAL A CB   1 
ATOM 5704 C CG1  . VAL A 1 387 ? 112.943 123.854 103.255 1.00 37.61  ? 387 VAL A CG1  1 
ATOM 5705 C CG2  . VAL A 1 387 ? 113.778 122.719 105.324 1.00 41.22  ? 387 VAL A CG2  1 
ATOM 5706 H H    . VAL A 1 387 ? 112.748 120.110 104.229 1.00 38.73  ? 387 VAL A H    1 
ATOM 5707 H HA   . VAL A 1 387 ? 111.311 122.215 104.910 1.00 39.66  ? 387 VAL A HA   1 
ATOM 5708 H HB   . VAL A 1 387 ? 113.690 121.961 103.431 1.00 39.82  ? 387 VAL A HB   1 
ATOM 5709 H HG11 . VAL A 1 387 ? 113.738 124.389 103.401 1.00 39.26  ? 387 VAL A HG11 1 
ATOM 5710 H HG12 . VAL A 1 387 ? 112.826 123.694 102.304 1.00 38.13  ? 387 VAL A HG12 1 
ATOM 5711 H HG13 . VAL A 1 387 ? 112.168 124.313 103.615 1.00 38.46  ? 387 VAL A HG13 1 
ATOM 5712 H HG21 . VAL A 1 387 ? 114.653 123.114 105.190 1.00 39.41  ? 387 VAL A HG21 1 
ATOM 5713 H HG22 . VAL A 1 387 ? 113.228 123.308 105.863 1.00 41.81  ? 387 VAL A HG22 1 
ATOM 5714 H HG23 . VAL A 1 387 ? 113.867 121.857 105.761 1.00 40.88  ? 387 VAL A HG23 1 
ATOM 5715 N N    . VAL A 1 388 ? 111.041 121.229 101.876 1.00 49.25  ? 388 VAL A N    1 
ATOM 5716 C CA   . VAL A 1 388 ? 110.324 121.462 100.628 1.00 42.50  ? 388 VAL A CA   1 
ATOM 5717 C C    . VAL A 1 388 ? 108.909 120.904 100.655 1.00 45.39  ? 388 VAL A C    1 
ATOM 5718 O O    . VAL A 1 388 ? 108.061 121.363 99.880  1.00 47.92  ? 388 VAL A O    1 
ATOM 5719 C CB   . VAL A 1 388 ? 111.085 120.853 99.438  1.00 39.65  ? 388 VAL A CB   1 
ATOM 5720 C CG1  . VAL A 1 388 ? 110.891 119.342 99.393  1.00 40.17  ? 388 VAL A CG1  1 
ATOM 5721 C CG2  . VAL A 1 388 ? 110.640 121.493 98.134  1.00 42.50  ? 388 VAL A CG2  1 
ATOM 5722 H H    . VAL A 1 388 ? 111.575 120.555 101.861 1.00 44.26  ? 388 VAL A H    1 
ATOM 5723 H HA   . VAL A 1 388 ? 110.263 122.418 100.479 1.00 41.53  ? 388 VAL A HA   1 
ATOM 5724 H HB   . VAL A 1 388 ? 112.032 121.028 99.548  1.00 41.25  ? 388 VAL A HB   1 
ATOM 5725 H HG11 . VAL A 1 388 ? 111.501 118.972 98.741  1.00 40.14  ? 388 VAL A HG11 1 
ATOM 5726 H HG12 . VAL A 1 388 ? 111.076 118.970 100.270 1.00 41.80  ? 388 VAL A HG12 1 
ATOM 5727 H HG13 . VAL A 1 388 ? 109.981 119.139 99.129  1.00 41.65  ? 388 VAL A HG13 1 
ATOM 5728 H HG21 . VAL A 1 388 ? 111.134 121.092 97.402  1.00 43.29  ? 388 VAL A HG21 1 
ATOM 5729 H HG22 . VAL A 1 388 ? 109.691 121.341 98.014  1.00 43.67  ? 388 VAL A HG22 1 
ATOM 5730 H HG23 . VAL A 1 388 ? 110.822 122.445 98.172  1.00 42.96  ? 388 VAL A HG23 1 
ATOM 5731 N N    . ASP A 1 389 ? 108.622 119.925 101.515 1.00 47.47  ? 389 ASP A N    1 
ATOM 5732 C CA   . ASP A 1 389 ? 107.268 119.381 101.556 1.00 48.92  ? 389 ASP A CA   1 
ATOM 5733 C C    . ASP A 1 389 ? 106.247 120.440 101.951 1.00 48.34  ? 389 ASP A C    1 
ATOM 5734 O O    . ASP A 1 389 ? 105.092 120.378 101.515 1.00 51.66  ? 389 ASP A O    1 
ATOM 5735 C CB   . ASP A 1 389 ? 107.200 118.202 102.525 1.00 58.16  ? 389 ASP A CB   1 
ATOM 5736 C CG   . ASP A 1 389 ? 106.509 116.993 101.924 1.00 70.65  ? 389 ASP A CG   1 
ATOM 5737 O OD1  . ASP A 1 389 ? 105.612 117.178 101.075 1.00 72.55  ? 389 ASP A OD1  1 
ATOM 5738 O OD2  . ASP A 1 389 ? 106.861 115.857 102.302 1.00 72.53  ? 389 ASP A OD2  1 
ATOM 5739 H H    . ASP A 1 389 ? 109.177 119.571 102.068 1.00 47.42  ? 389 ASP A H    1 
ATOM 5740 H HA   . ASP A 1 389 ? 107.036 119.059 100.671 1.00 51.00  ? 389 ASP A HA   1 
ATOM 5741 H HB2  . ASP A 1 389 ? 108.101 117.940 102.771 1.00 54.05  ? 389 ASP A HB2  1 
ATOM 5742 H HB3  . ASP A 1 389 ? 106.706 118.469 103.315 1.00 56.91  ? 389 ASP A HB3  1 
ATOM 5743 N N    . ILE A 1 390 ? 106.644 121.407 102.771 1.00 47.80  ? 390 ILE A N    1 
ATOM 5744 C CA   . ILE A 1 390 ? 105.709 122.372 103.344 1.00 50.69  ? 390 ILE A CA   1 
ATOM 5745 C C    . ILE A 1 390 ? 105.186 123.299 102.248 1.00 53.25  ? 390 ILE A C    1 
ATOM 5746 O O    . ILE A 1 390 ? 103.959 123.392 102.057 1.00 59.54  ? 390 ILE A O    1 
ATOM 5747 C CB   . ILE A 1 390 ? 106.372 123.154 104.490 1.00 49.59  ? 390 ILE A CB   1 
ATOM 5748 C CG1  . ILE A 1 390 ? 106.467 122.282 105.743 1.00 55.69  ? 390 ILE A CG1  1 
ATOM 5749 C CG2  . ILE A 1 390 ? 105.589 124.421 104.790 1.00 52.33  ? 390 ILE A CG2  1 
ATOM 5750 C CD1  . ILE A 1 390 ? 107.465 122.783 106.761 1.00 56.84  ? 390 ILE A CD1  1 
ATOM 5751 H H    . ILE A 1 390 ? 107.459 121.527 103.014 1.00 48.81  ? 390 ILE A H    1 
ATOM 5752 H HA   . ILE A 1 390 ? 104.953 121.890 103.712 1.00 51.79  ? 390 ILE A HA   1 
ATOM 5753 H HB   . ILE A 1 390 ? 107.275 123.390 104.245 1.00 49.07  ? 390 ILE A HB   1 
ATOM 5754 H HG12 . ILE A 1 390 ? 105.604 122.251 106.171 1.00 56.74  ? 390 ILE A HG12 1 
ATOM 5755 H HG13 . ILE A 1 390 ? 106.738 121.389 105.482 1.00 53.68  ? 390 ILE A HG13 1 
ATOM 5756 H HG21 . ILE A 1 390 ? 104.641 124.215 104.773 1.00 53.76  ? 390 ILE A HG21 1 
ATOM 5757 H HG22 . ILE A 1 390 ? 105.839 124.746 105.667 1.00 53.38  ? 390 ILE A HG22 1 
ATOM 5758 H HG23 . ILE A 1 390 ? 105.796 125.088 104.118 1.00 51.35  ? 390 ILE A HG23 1 
ATOM 5759 H HD11 . ILE A 1 390 ? 108.330 122.880 106.332 1.00 53.05  ? 390 ILE A HD11 1 
ATOM 5760 H HD12 . ILE A 1 390 ? 107.167 123.640 107.103 1.00 56.22  ? 390 ILE A HD12 1 
ATOM 5761 H HD13 . ILE A 1 390 ? 107.526 122.141 107.486 1.00 57.14  ? 390 ILE A HD13 1 
ATOM 5762 N N    . PRO A 1 391 ? 106.054 124.006 101.507 1.00 47.76  ? 391 PRO A N    1 
ATOM 5763 C CA   . PRO A 1 391 ? 105.530 124.923 100.479 1.00 48.69  ? 391 PRO A CA   1 
ATOM 5764 C C    . PRO A 1 391 ? 104.656 124.242 99.444  1.00 49.82  ? 391 PRO A C    1 
ATOM 5765 O O    . PRO A 1 391 ? 103.667 124.829 98.997  1.00 54.11  ? 391 PRO A O    1 
ATOM 5766 C CB   . PRO A 1 391 ? 106.803 125.496 99.845  1.00 53.40  ? 391 PRO A CB   1 
ATOM 5767 C CG   . PRO A 1 391 ? 107.834 125.369 100.883 1.00 55.46  ? 391 PRO A CG   1 
ATOM 5768 C CD   . PRO A 1 391 ? 107.522 124.099 101.608 1.00 51.67  ? 391 PRO A CD   1 
ATOM 5769 H HA   . PRO A 1 391 ? 105.033 125.643 100.898 1.00 50.01  ? 391 PRO A HA   1 
ATOM 5770 H HB2  . PRO A 1 391 ? 107.042 124.981 99.058  1.00 52.32  ? 391 PRO A HB2  1 
ATOM 5771 H HB3  . PRO A 1 391 ? 106.662 126.429 99.617  1.00 53.09  ? 391 PRO A HB3  1 
ATOM 5772 H HG2  . PRO A 1 391 ? 108.709 125.322 100.468 1.00 51.72  ? 391 PRO A HG2  1 
ATOM 5773 H HG3  . PRO A 1 391 ? 107.782 126.127 101.486 1.00 52.85  ? 391 PRO A HG3  1 
ATOM 5774 H HD2  . PRO A 1 391 ? 107.947 123.347 101.168 1.00 50.55  ? 391 PRO A HD2  1 
ATOM 5775 H HD3  . PRO A 1 391 ? 107.817 124.189 102.521 1.00 50.38  ? 391 PRO A HD3  1 
ATOM 5776 N N    . ALA A 1 392 ? 105.004 123.021 99.028  1.00 44.96  ? 392 ALA A N    1 
ATOM 5777 C CA   . ALA A 1 392 ? 104.188 122.331 98.034  1.00 47.07  ? 392 ALA A CA   1 
ATOM 5778 C C    . ALA A 1 392 ? 102.797 122.042 98.580  1.00 48.85  ? 392 ALA A C    1 
ATOM 5779 O O    . ALA A 1 392 ? 101.792 122.242 97.885  1.00 53.72  ? 392 ALA A O    1 
ATOM 5780 C CB   . ALA A 1 392 ? 104.874 121.039 97.598  1.00 49.24  ? 392 ALA A CB   1 
ATOM 5781 H H    . ALA A 1 392 ? 105.692 122.582 99.298  1.00 48.11  ? 392 ALA A H    1 
ATOM 5782 H HA   . ALA A 1 392 ? 104.094 122.900 97.254  1.00 48.60  ? 392 ALA A HA   1 
ATOM 5783 H HB1  . ALA A 1 392 ? 105.738 121.256 97.212  1.00 49.04  ? 392 ALA A HB1  1 
ATOM 5784 H HB2  . ALA A 1 392 ? 104.990 120.466 98.372  1.00 48.29  ? 392 ALA A HB2  1 
ATOM 5785 H HB3  . ALA A 1 392 ? 104.318 120.595 96.938  1.00 52.28  ? 392 ALA A HB3  1 
ATOM 5786 N N    . LYS A 1 393 ? 102.718 121.576 99.828  1.00 47.48  ? 393 LYS A N    1 
ATOM 5787 C CA   . LYS A 1 393 ? 101.421 121.315 100.439 1.00 49.63  ? 393 LYS A CA   1 
ATOM 5788 C C    . LYS A 1 393 ? 100.600 122.588 100.571 1.00 49.32  ? 393 LYS A C    1 
ATOM 5789 O O    . LYS A 1 393 ? 99.376  122.553 100.395 1.00 56.57  ? 393 LYS A O    1 
ATOM 5790 C CB   . LYS A 1 393 ? 101.607 120.672 101.812 1.00 51.30  ? 393 LYS A CB   1 
ATOM 5791 C CG   . LYS A 1 393 ? 101.914 119.188 101.767 1.00 52.62  ? 393 LYS A CG   1 
ATOM 5792 C CD   . LYS A 1 393 ? 102.034 118.609 103.166 1.00 58.64  ? 393 LYS A CD   1 
ATOM 5793 C CE   . LYS A 1 393 ? 102.590 117.197 103.140 1.00 62.88  ? 393 LYS A CE   1 
ATOM 5794 N NZ   . LYS A 1 393 ? 101.990 116.359 104.215 1.00 63.18  ? 393 LYS A NZ   1 
ATOM 5795 H H    . LYS A 1 393 ? 103.393 121.402 100.331 1.00 50.44  ? 393 LYS A H    1 
ATOM 5796 H HA   . LYS A 1 393 ? 100.924 120.695 99.881  1.00 51.03  ? 393 LYS A HA   1 
ATOM 5797 H HB2  . LYS A 1 393 ? 102.343 121.114 102.263 1.00 52.31  ? 393 LYS A HB2  1 
ATOM 5798 H HB3  . LYS A 1 393 ? 100.790 120.791 102.323 1.00 52.71  ? 393 LYS A HB3  1 
ATOM 5799 H HG2  . LYS A 1 393 ? 101.199 118.724 101.304 1.00 53.02  ? 393 LYS A HG2  1 
ATOM 5800 H HG3  . LYS A 1 393 ? 102.757 119.052 101.309 1.00 54.53  ? 393 LYS A HG3  1 
ATOM 5801 H HD2  . LYS A 1 393 ? 102.637 119.162 103.688 1.00 57.41  ? 393 LYS A HD2  1 
ATOM 5802 H HD3  . LYS A 1 393 ? 101.158 118.585 103.581 1.00 59.24  ? 393 LYS A HD3  1 
ATOM 5803 H HE2  . LYS A 1 393 ? 102.381 116.789 102.285 1.00 62.77  ? 393 LYS A HE2  1 
ATOM 5804 H HE3  . LYS A 1 393 ? 103.549 117.227 103.269 1.00 60.91  ? 393 LYS A HE3  1 
ATOM 5805 H HZ1  . LYS A 1 393 ? 101.839 116.856 104.938 1.00 61.75  ? 393 LYS A HZ1  1 
ATOM 5806 H HZ2  . LYS A 1 393 ? 101.218 116.015 103.934 1.00 62.26  ? 393 LYS A HZ2  1 
ATOM 5807 H HZ3  . LYS A 1 393 ? 102.543 115.695 104.427 1.00 63.48  ? 393 LYS A HZ3  1 
ATOM 5808 N N    . ILE A 1 394 ? 101.242 123.715 100.878 1.00 46.08  ? 394 ILE A N    1 
ATOM 5809 C CA   . ILE A 1 394 ? 100.489 124.962 100.988 1.00 44.30  ? 394 ILE A CA   1 
ATOM 5810 C C    . ILE A 1 394 ? 100.020 125.437 99.616  1.00 50.96  ? 394 ILE A C    1 
ATOM 5811 O O    . ILE A 1 394 ? 98.892  125.921 99.468  1.00 57.63  ? 394 ILE A O    1 
ATOM 5812 C CB   . ILE A 1 394 ? 101.334 126.030 101.701 1.00 52.61  ? 394 ILE A CB   1 
ATOM 5813 C CG1  . ILE A 1 394 ? 101.417 125.722 103.196 1.00 55.52  ? 394 ILE A CG1  1 
ATOM 5814 C CG2  . ILE A 1 394 ? 100.738 127.412 101.488 1.00 53.92  ? 394 ILE A CG2  1 
ATOM 5815 C CD1  . ILE A 1 394 ? 102.761 126.040 103.806 1.00 55.71  ? 394 ILE A CD1  1 
ATOM 5816 H H    . ILE A 1 394 ? 102.086 123.781 101.028 1.00 50.07  ? 394 ILE A H    1 
ATOM 5817 H HA   . ILE A 1 394 ? 99.702  124.803 101.529 1.00 46.70  ? 394 ILE A HA   1 
ATOM 5818 H HB   . ILE A 1 394 ? 102.230 126.018 101.331 1.00 52.88  ? 394 ILE A HB   1 
ATOM 5819 H HG12 . ILE A 1 394 ? 100.750 126.251 103.661 1.00 56.07  ? 394 ILE A HG12 1 
ATOM 5820 H HG13 . ILE A 1 394 ? 101.243 124.778 103.333 1.00 52.67  ? 394 ILE A HG13 1 
ATOM 5821 H HG21 . ILE A 1 394 ? 101.092 128.013 102.162 1.00 54.08  ? 394 ILE A HG21 1 
ATOM 5822 H HG22 . ILE A 1 394 ? 100.979 127.730 100.605 1.00 53.70  ? 394 ILE A HG22 1 
ATOM 5823 H HG23 . ILE A 1 394 ? 99.773  127.356 101.573 1.00 52.57  ? 394 ILE A HG23 1 
ATOM 5824 H HD11 . ILE A 1 394 ? 102.896 127.001 103.790 1.00 55.00  ? 394 ILE A HD11 1 
ATOM 5825 H HD12 . ILE A 1 394 ? 102.776 125.719 104.721 1.00 54.43  ? 394 ILE A HD12 1 
ATOM 5826 H HD13 . ILE A 1 394 ? 103.453 125.599 103.289 1.00 53.30  ? 394 ILE A HD13 1 
ATOM 5827 N N    . GLY A 1 395 ? 100.868 125.308 98.594  1.00 50.31  ? 395 GLY A N    1 
ATOM 5828 C CA   . GLY A 1 395 ? 100.515 125.810 97.277  1.00 50.94  ? 395 GLY A CA   1 
ATOM 5829 C C    . GLY A 1 395 ? 99.499  124.951 96.554  1.00 58.79  ? 395 GLY A C    1 
ATOM 5830 O O    . GLY A 1 395 ? 98.786  125.440 95.671  1.00 68.36  ? 395 GLY A O    1 
ATOM 5831 H H    . GLY A 1 395 ? 101.642 124.937 98.641  1.00 51.16  ? 395 GLY A H    1 
ATOM 5832 H HA2  . GLY A 1 395 ? 100.147 126.703 97.368  1.00 51.42  ? 395 GLY A HA2  1 
ATOM 5833 H HA3  . GLY A 1 395 ? 101.315 125.862 96.730  1.00 51.64  ? 395 GLY A HA3  1 
ATOM 5834 N N    . THR A 1 396 ? 99.417  123.666 96.906  1.00 53.23  ? 396 THR A N    1 
ATOM 5835 C CA   . THR A 1 396 ? 98.414  122.806 96.289  1.00 51.70  ? 396 THR A CA   1 
ATOM 5836 C C    . THR A 1 396 ? 97.005  123.300 96.588  1.00 54.84  ? 396 THR A C    1 
ATOM 5837 O O    . THR A 1 396 ? 96.123  123.246 95.723  1.00 62.30  ? 396 THR A O    1 
ATOM 5838 C CB   . THR A 1 396 ? 98.585  121.366 96.768  1.00 53.13  ? 396 THR A CB   1 
ATOM 5839 O OG1  . THR A 1 396 ? 98.563  121.327 98.201  1.00 57.23  ? 396 THR A OG1  1 
ATOM 5840 C CG2  . THR A 1 396 ? 99.891  120.785 96.257  1.00 49.49  ? 396 THR A CG2  1 
ATOM 5841 H H    . THR A 1 396 ? 99.920  123.278 97.486  1.00 53.47  ? 396 THR A H    1 
ATOM 5842 H HA   . THR A 1 396 ? 98.536  122.819 95.326  1.00 53.04  ? 396 THR A HA   1 
ATOM 5843 H HB   . THR A 1 396 ? 97.857  120.826 96.423  1.00 54.98  ? 396 THR A HB   1 
ATOM 5844 H HG1  . THR A 1 396 ? 98.604  120.532 98.469  1.00 55.30  ? 396 THR A HG1  1 
ATOM 5845 H HG21 . THR A 1 396 ? 100.314 120.256 96.952  1.00 50.15  ? 396 THR A HG21 1 
ATOM 5846 H HG22 . THR A 1 396 ? 99.719  120.218 95.489  1.00 49.57  ? 396 THR A HG22 1 
ATOM 5847 H HG23 . THR A 1 396 ? 100.493 121.498 95.993  1.00 51.96  ? 396 THR A HG23 1 
ATOM 5848 N N    . LEU A 1 397 ? 96.767  123.776 97.812  1.00 53.05  ? 397 LEU A N    1 
ATOM 5849 C CA   . LEU A 1 397 ? 95.439  124.274 98.160  1.00 54.44  ? 397 LEU A CA   1 
ATOM 5850 C C    . LEU A 1 397 ? 95.074  125.497 97.326  1.00 58.93  ? 397 LEU A C    1 
ATOM 5851 O O    . LEU A 1 397 ? 93.947  125.606 96.829  1.00 65.53  ? 397 LEU A O    1 
ATOM 5852 C CB   . LEU A 1 397 ? 95.368  124.598 99.654  1.00 54.31  ? 397 LEU A CB   1 
ATOM 5853 C CG   . LEU A 1 397 ? 96.204  123.733 100.604 1.00 53.08  ? 397 LEU A CG   1 
ATOM 5854 C CD1  . LEU A 1 397 ? 95.959  124.139 102.045 1.00 56.14  ? 397 LEU A CD1  1 
ATOM 5855 C CD2  . LEU A 1 397 ? 95.903  122.254 100.408 1.00 54.02  ? 397 LEU A CD2  1 
ATOM 5856 H H    . LEU A 1 397 ? 97.353  123.827 98.437  1.00 54.51  ? 397 LEU A H    1 
ATOM 5857 H HA   . LEU A 1 397 ? 94.786  123.581 97.974  1.00 55.19  ? 397 LEU A HA   1 
ATOM 5858 H HB2  . LEU A 1 397 ? 95.657  125.516 99.776  1.00 56.36  ? 397 LEU A HB2  1 
ATOM 5859 H HB3  . LEU A 1 397 ? 94.444  124.516 99.935  1.00 54.71  ? 397 LEU A HB3  1 
ATOM 5860 H HG   . LEU A 1 397 ? 97.145  123.873 100.418 1.00 53.60  ? 397 LEU A HG   1 
ATOM 5861 H HD11 . LEU A 1 397 ? 96.496  123.578 102.626 1.00 58.42  ? 397 LEU A HD11 1 
ATOM 5862 H HD12 . LEU A 1 397 ? 96.209  125.070 102.158 1.00 56.43  ? 397 LEU A HD12 1 
ATOM 5863 H HD13 . LEU A 1 397 ? 95.018  124.022 102.250 1.00 56.84  ? 397 LEU A HD13 1 
ATOM 5864 H HD21 . LEU A 1 397 ? 96.435  121.740 101.035 1.00 54.86  ? 397 LEU A HD21 1 
ATOM 5865 H HD22 . LEU A 1 397 ? 94.959  122.101 100.573 1.00 53.59  ? 397 LEU A HD22 1 
ATOM 5866 H HD23 . LEU A 1 397 ? 96.125  121.997 99.500  1.00 55.91  ? 397 LEU A HD23 1 
ATOM 5867 N N    . LEU A 1 398 ? 96.016  126.429 97.159  1.00 60.18  ? 398 LEU A N    1 
ATOM 5868 C CA   . LEU A 1 398 ? 95.753  127.593 96.320  1.00 66.57  ? 398 LEU A CA   1 
ATOM 5869 C C    . LEU A 1 398 ? 95.504  127.178 94.877  1.00 70.74  ? 398 LEU A C    1 
ATOM 5870 O O    . LEU A 1 398 ? 94.611  127.719 94.212  1.00 71.97  ? 398 LEU A O    1 
ATOM 5871 C CB   . LEU A 1 398 ? 96.920  128.577 96.402  1.00 68.84  ? 398 LEU A CB   1 
ATOM 5872 C CG   . LEU A 1 398 ? 96.811  129.822 95.516  1.00 79.55  ? 398 LEU A CG   1 
ATOM 5873 C CD1  . LEU A 1 398 ? 95.560  130.621 95.850  1.00 82.65  ? 398 LEU A CD1  1 
ATOM 5874 C CD2  . LEU A 1 398 ? 98.053  130.686 95.663  1.00 83.48  ? 398 LEU A CD2  1 
ATOM 5875 H H    . LEU A 1 398 ? 96.800  126.409 97.513  1.00 60.31  ? 398 LEU A H    1 
ATOM 5876 H HA   . LEU A 1 398 ? 94.957  128.041 96.645  1.00 66.98  ? 398 LEU A HA   1 
ATOM 5877 H HB2  . LEU A 1 398 ? 96.999  128.881 97.319  1.00 68.29  ? 398 LEU A HB2  1 
ATOM 5878 H HB3  . LEU A 1 398 ? 97.731  128.111 96.145  1.00 66.30  ? 398 LEU A HB3  1 
ATOM 5879 H HG   . LEU A 1 398 ? 96.750  129.548 94.588  1.00 76.22  ? 398 LEU A HG   1 
ATOM 5880 H HD11 . LEU A 1 398 ? 94.779  130.116 95.577  1.00 75.85  ? 398 LEU A HD11 1 
ATOM 5881 H HD12 . LEU A 1 398 ? 95.534  130.782 96.807  1.00 80.34  ? 398 LEU A HD12 1 
ATOM 5882 H HD13 . LEU A 1 398 ? 95.590  131.466 95.373  1.00 84.02  ? 398 LEU A HD13 1 
ATOM 5883 H HD21 . LEU A 1 398 ? 98.144  130.952 96.592  1.00 82.04  ? 398 LEU A HD21 1 
ATOM 5884 H HD22 . LEU A 1 398 ? 98.829  130.173 95.388  1.00 80.44  ? 398 LEU A HD22 1 
ATOM 5885 H HD23 . LEU A 1 398 ? 97.960  131.471 95.102  1.00 81.95  ? 398 LEU A HD23 1 
ATOM 5886 N N    . LEU A 1 399 ? 96.285  126.221 94.373  1.00 67.18  ? 399 LEU A N    1 
ATOM 5887 C CA   . LEU A 1 399 ? 96.066  125.734 93.016  1.00 64.66  ? 399 LEU A CA   1 
ATOM 5888 C C    . LEU A 1 399 ? 94.661  125.169 92.868  1.00 68.13  ? 399 LEU A C    1 
ATOM 5889 O O    . LEU A 1 399 ? 93.951  125.476 91.905  1.00 71.94  ? 399 LEU A O    1 
ATOM 5890 C CB   . LEU A 1 399 ? 97.113  124.677 92.663  1.00 62.78  ? 399 LEU A CB   1 
ATOM 5891 C CG   . LEU A 1 399 ? 98.153  125.093 91.623  1.00 75.16  ? 399 LEU A CG   1 
ATOM 5892 C CD1  . LEU A 1 399 ? 99.122  126.105 92.208  1.00 79.07  ? 399 LEU A CD1  1 
ATOM 5893 C CD2  . LEU A 1 399 ? 98.901  123.877 91.108  1.00 68.45  ? 399 LEU A CD2  1 
ATOM 5894 H H    . LEU A 1 399 ? 96.936  125.847 94.791  1.00 65.53  ? 399 LEU A H    1 
ATOM 5895 H HA   . LEU A 1 399 ? 96.161  126.473 92.394  1.00 66.95  ? 399 LEU A HA   1 
ATOM 5896 H HB2  . LEU A 1 399 ? 97.591  124.433 93.470  1.00 62.94  ? 399 LEU A HB2  1 
ATOM 5897 H HB3  . LEU A 1 399 ? 96.652  123.898 92.314  1.00 65.08  ? 399 LEU A HB3  1 
ATOM 5898 H HG   . LEU A 1 399 ? 97.702  125.509 90.872  1.00 73.88  ? 399 LEU A HG   1 
ATOM 5899 H HD11 . LEU A 1 399 ? 98.627  126.892 92.485  1.00 73.69  ? 399 LEU A HD11 1 
ATOM 5900 H HD12 . LEU A 1 399 ? 99.568  125.709 92.973  1.00 71.85  ? 399 LEU A HD12 1 
ATOM 5901 H HD13 . LEU A 1 399 ? 99.773  126.345 91.531  1.00 78.74  ? 399 LEU A HD13 1 
ATOM 5902 H HD21 . LEU A 1 399 ? 99.338  123.437 91.853  1.00 69.11  ? 399 LEU A HD21 1 
ATOM 5903 H HD22 . LEU A 1 399 ? 98.268  123.271 90.690  1.00 68.74  ? 399 LEU A HD22 1 
ATOM 5904 H HD23 . LEU A 1 399 ? 99.561  124.164 90.458  1.00 69.91  ? 399 LEU A HD23 1 
ATOM 5905 N N    . LEU A 1 400 ? 94.233  124.352 93.832  1.00 67.50  ? 400 LEU A N    1 
ATOM 5906 C CA   . LEU A 1 400 ? 92.887  123.793 93.779  1.00 60.50  ? 400 LEU A CA   1 
ATOM 5907 C C    . LEU A 1 400 ? 91.838  124.896 93.808  1.00 57.37  ? 400 LEU A C    1 
ATOM 5908 O O    . LEU A 1 400 ? 90.829  124.824 93.096  1.00 59.34  ? 400 LEU A O    1 
ATOM 5909 C CB   . LEU A 1 400 ? 92.676  122.823 94.941  1.00 58.40  ? 400 LEU A CB   1 
ATOM 5910 C CG   . LEU A 1 400 ? 93.490  121.527 94.905  1.00 60.50  ? 400 LEU A CG   1 
ATOM 5911 C CD1  . LEU A 1 400 ? 93.120  120.640 96.080  1.00 57.94  ? 400 LEU A CD1  1 
ATOM 5912 C CD2  . LEU A 1 400 ? 93.284  120.792 93.592  1.00 59.15  ? 400 LEU A CD2  1 
ATOM 5913 H H    . LEU A 1 400 ? 94.695  124.113 94.516  1.00 64.90  ? 400 LEU A H    1 
ATOM 5914 H HA   . LEU A 1 400 ? 92.780  123.306 92.947  1.00 61.32  ? 400 LEU A HA   1 
ATOM 5915 H HB2  . LEU A 1 400 ? 92.903  123.282 95.764  1.00 60.28  ? 400 LEU A HB2  1 
ATOM 5916 H HB3  . LEU A 1 400 ? 91.739  122.573 94.961  1.00 58.20  ? 400 LEU A HB3  1 
ATOM 5917 H HG   . LEU A 1 400 ? 94.431  121.744 94.979  1.00 61.11  ? 400 LEU A HG   1 
ATOM 5918 H HD11 . LEU A 1 400 ? 93.655  119.832 96.046  1.00 57.74  ? 400 LEU A HD11 1 
ATOM 5919 H HD12 . LEU A 1 400 ? 93.297  121.120 96.904  1.00 58.26  ? 400 LEU A HD12 1 
ATOM 5920 H HD13 . LEU A 1 400 ? 92.178  120.417 96.022  1.00 57.61  ? 400 LEU A HD13 1 
ATOM 5921 H HD21 . LEU A 1 400 ? 92.352  120.863 93.334  1.00 59.74  ? 400 LEU A HD21 1 
ATOM 5922 H HD22 . LEU A 1 400 ? 93.846  121.197 92.913  1.00 59.68  ? 400 LEU A HD22 1 
ATOM 5923 H HD23 . LEU A 1 400 ? 93.529  119.860 93.709  1.00 61.23  ? 400 LEU A HD23 1 
ATOM 5924 N N    . SER A 1 401 ? 92.055  125.922 94.630  1.00 64.31  ? 401 SER A N    1 
ATOM 5925 C CA   . SER A 1 401 ? 91.104  127.027 94.694  1.00 73.81  ? 401 SER A CA   1 
ATOM 5926 C C    . SER A 1 401 ? 90.991  127.734 93.347  1.00 67.09  ? 401 SER A C    1 
ATOM 5927 O O    . SER A 1 401 ? 89.884  128.018 92.875  1.00 67.94  ? 401 SER A O    1 
ATOM 5928 C CB   . SER A 1 401 ? 91.520  128.010 95.789  1.00 83.35  ? 401 SER A CB   1 
ATOM 5929 O OG   . SER A 1 401 ? 91.005  127.617 97.050  1.00 77.52  ? 401 SER A OG   1 
ATOM 5930 H H    . SER A 1 401 ? 92.733  126.001 95.154  1.00 66.84  ? 401 SER A H    1 
ATOM 5931 H HA   . SER A 1 401 ? 90.229  126.677 94.924  1.00 70.25  ? 401 SER A HA   1 
ATOM 5932 H HB2  . SER A 1 401 ? 92.488  128.037 95.840  1.00 75.65  ? 401 SER A HB2  1 
ATOM 5933 H HB3  . SER A 1 401 ? 91.175  128.890 95.570  1.00 78.39  ? 401 SER A HB3  1 
ATOM 5934 H HG   . SER A 1 401 ? 90.165  127.602 97.027  1.00 75.43  ? 401 SER A HG   1 
ATOM 5935 N N    . ARG A 1 402 ? 92.126  128.022 92.709  1.00 61.10  ? 402 ARG A N    1 
ATOM 5936 C CA   . ARG A 1 402 ? 92.149  128.761 91.451  1.00 66.55  ? 402 ARG A CA   1 
ATOM 5937 C C    . ARG A 1 402 ? 92.409  127.883 90.231  1.00 74.71  ? 402 ARG A C    1 
ATOM 5938 O O    . ARG A 1 402 ? 92.676  128.414 89.149  1.00 82.69  ? 402 ARG A O    1 
ATOM 5939 C CB   . ARG A 1 402 ? 93.193  129.879 91.511  1.00 80.00  ? 402 ARG A CB   1 
ATOM 5940 C CG   . ARG A 1 402 ? 92.686  131.158 92.182  1.00 82.81  ? 402 ARG A CG   1 
ATOM 5941 C CD   . ARG A 1 402 ? 91.970  132.121 91.216  1.00 84.00  ? 402 ARG A CD   1 
ATOM 5942 N NE   . ARG A 1 402 ? 92.379  131.992 89.821  1.00 87.70  ? 402 ARG A NE   1 
ATOM 5943 C CZ   . ARG A 1 402 ? 91.890  132.730 88.833  1.00 88.44  ? 402 ARG A CZ   1 
ATOM 5944 N NH1  . ARG A 1 402 ? 90.970  133.656 89.052  1.00 84.31  ? 402 ARG A NH1  1 
ATOM 5945 N NH2  . ARG A 1 402 ? 92.332  132.532 87.593  1.00 90.31  ? 402 ARG A NH2  1 
ATOM 5946 H H    . ARG A 1 402 ? 92.906  127.799 92.994  1.00 66.62  ? 402 ARG A H    1 
ATOM 5947 H HA   . ARG A 1 402 ? 91.284  129.181 91.322  1.00 68.50  ? 402 ARG A HA   1 
ATOM 5948 H HB2  . ARG A 1 402 ? 93.943  129.563 92.037  1.00 78.48  ? 402 ARG A HB2  1 
ATOM 5949 H HB3  . ARG A 1 402 ? 93.498  130.072 90.616  1.00 79.23  ? 402 ARG A HB3  1 
ATOM 5950 H HG2  . ARG A 1 402 ? 92.056  130.915 92.879  1.00 82.02  ? 402 ARG A HG2  1 
ATOM 5951 H HG3  . ARG A 1 402 ? 93.441  131.631 92.568  1.00 79.19  ? 402 ARG A HG3  1 
ATOM 5952 H HD2  . ARG A 1 402 ? 91.016  131.946 91.254  1.00 83.77  ? 402 ARG A HD2  1 
ATOM 5953 H HD3  . ARG A 1 402 ? 92.153  133.033 91.493  1.00 82.83  ? 402 ARG A HD3  1 
ATOM 5954 H HE   . ARG A 1 402 ? 93.183  131.717 89.701  1.00 87.13  ? 402 ARG A HE   1 
ATOM 5955 H HH11 . ARG A 1 402 ? 90.674  133.795 89.847  1.00 82.46  ? 402 ARG A HH11 1 
ATOM 5956 H HH12 . ARG A 1 402 ? 90.667  134.122 88.396  1.00 83.14  ? 402 ARG A HH12 1 
ATOM 5957 H HH21 . ARG A 1 402 ? 92.930  131.933 87.438  1.00 89.71  ? 402 ARG A HH21 1 
ATOM 5958 H HH22 . ARG A 1 402 ? 92.023  133.004 86.943  1.00 88.23  ? 402 ARG A HH22 1 
ATOM 5959 N N    . LEU A 1 403 ? 92.341  126.562 90.370  1.00 76.06  ? 403 LEU A N    1 
ATOM 5960 C CA   . LEU A 1 403 ? 92.495  125.685 89.218  1.00 65.97  ? 403 LEU A CA   1 
ATOM 5961 C C    . LEU A 1 403 ? 91.731  124.396 89.471  1.00 63.82  ? 403 LEU A C    1 
ATOM 5962 O O    . LEU A 1 403 ? 91.403  124.057 90.611  1.00 70.58  ? 403 LEU A O    1 
ATOM 5963 C CB   . LEU A 1 403 ? 93.972  125.387 88.919  1.00 64.91  ? 403 LEU A CB   1 
ATOM 5964 C CG   . LEU A 1 403 ? 94.609  126.112 87.728  1.00 71.00  ? 403 LEU A CG   1 
ATOM 5965 C CD1  . LEU A 1 403 ? 96.051  125.663 87.551  1.00 64.72  ? 403 LEU A CD1  1 
ATOM 5966 C CD2  . LEU A 1 403 ? 93.820  125.880 86.446  1.00 72.92  ? 403 LEU A CD2  1 
ATOM 5967 H H    . LEU A 1 403 ? 92.205  126.154 91.114  1.00 71.58  ? 403 LEU A H    1 
ATOM 5968 H HA   . LEU A 1 403 ? 92.101  126.116 88.444  1.00 67.31  ? 403 LEU A HA   1 
ATOM 5969 H HB2  . LEU A 1 403 ? 94.498  125.622 89.697  1.00 68.50  ? 403 LEU A HB2  1 
ATOM 5970 H HB3  . LEU A 1 403 ? 94.058  124.435 88.751  1.00 66.45  ? 403 LEU A HB3  1 
ATOM 5971 H HG   . LEU A 1 403 ? 94.614  127.065 87.907  1.00 72.50  ? 403 LEU A HG   1 
ATOM 5972 H HD11 . LEU A 1 403 ? 96.441  126.141 86.803  1.00 68.19  ? 403 LEU A HD11 1 
ATOM 5973 H HD12 . LEU A 1 403 ? 96.545  125.858 88.363  1.00 67.21  ? 403 LEU A HD12 1 
ATOM 5974 H HD13 . LEU A 1 403 ? 96.063  124.709 87.378  1.00 62.62  ? 403 LEU A HD13 1 
ATOM 5975 H HD21 . LEU A 1 403 ? 93.028  126.439 86.453  1.00 72.69  ? 403 LEU A HD21 1 
ATOM 5976 H HD22 . LEU A 1 403 ? 94.380  126.111 85.688  1.00 72.71  ? 403 LEU A HD22 1 
ATOM 5977 H HD23 . LEU A 1 403 ? 93.568  124.944 86.396  1.00 72.06  ? 403 LEU A HD23 1 
ATOM 5978 N N    . GLY A 1 404 ? 91.449  123.678 88.388  1.00 57.11  ? 404 GLY A N    1 
ATOM 5979 C CA   . GLY A 1 404 ? 90.709  122.440 88.505  1.00 59.60  ? 404 GLY A CA   1 
ATOM 5980 C C    . GLY A 1 404 ? 91.464  121.396 89.304  1.00 53.11  ? 404 GLY A C    1 
ATOM 5981 O O    . GLY A 1 404 ? 92.690  121.413 89.415  1.00 51.88  ? 404 GLY A O    1 
ATOM 5982 H H    . GLY A 1 404 ? 91.673  123.890 87.585  1.00 60.66  ? 404 GLY A H    1 
ATOM 5983 H HA2  . GLY A 1 404 ? 89.860  122.610 88.943  1.00 61.16  ? 404 GLY A HA2  1 
ATOM 5984 H HA3  . GLY A 1 404 ? 90.533  122.083 87.620  1.00 59.93  ? 404 GLY A HA3  1 
ATOM 5985 N N    . ARG A 1 405 ? 90.697  120.469 89.879  1.00 47.06  ? 405 ARG A N    1 
ATOM 5986 C CA   . ARG A 1 405 ? 91.300  119.390 90.654  1.00 48.33  ? 405 ARG A CA   1 
ATOM 5987 C C    . ARG A 1 405 ? 91.985  118.377 89.746  1.00 50.51  ? 405 ARG A C    1 
ATOM 5988 O O    . ARG A 1 405 ? 93.106  117.936 90.028  1.00 53.32  ? 405 ARG A O    1 
ATOM 5989 C CB   . ARG A 1 405 ? 90.228  118.709 91.505  1.00 52.27  ? 405 ARG A CB   1 
ATOM 5990 C CG   . ARG A 1 405 ? 90.693  118.275 92.884  1.00 56.61  ? 405 ARG A CG   1 
ATOM 5991 C CD   . ARG A 1 405 ? 89.548  118.276 93.886  1.00 64.81  ? 405 ARG A CD   1 
ATOM 5992 N NE   . ARG A 1 405 ? 89.350  119.585 94.502  1.00 68.55  ? 405 ARG A NE   1 
ATOM 5993 C CZ   . ARG A 1 405 ? 88.450  120.480 94.115  1.00 69.89  ? 405 ARG A CZ   1 
ATOM 5994 N NH1  . ARG A 1 405 ? 87.630  120.250 93.102  1.00 60.46  ? 405 ARG A NH1  1 
ATOM 5995 N NH2  . ARG A 1 405 ? 88.369  121.638 94.764  1.00 81.53  ? 405 ARG A NH2  1 
ATOM 5996 H H    . ARG A 1 405 ? 89.839  120.445 89.836  1.00 50.03  ? 405 ARG A H    1 
ATOM 5997 H HA   . ARG A 1 405 ? 91.969  119.764 91.248  1.00 53.05  ? 405 ARG A HA   1 
ATOM 5998 H HB2  . ARG A 1 405 ? 89.491  119.327 91.624  1.00 54.10  ? 405 ARG A HB2  1 
ATOM 5999 H HB3  . ARG A 1 405 ? 89.917  117.918 91.037  1.00 54.94  ? 405 ARG A HB3  1 
ATOM 6000 H HG2  . ARG A 1 405 ? 91.050  117.375 92.831  1.00 57.91  ? 405 ARG A HG2  1 
ATOM 6001 H HG3  . ARG A 1 405 ? 91.374  118.885 93.203  1.00 56.21  ? 405 ARG A HG3  1 
ATOM 6002 H HD2  . ARG A 1 405 ? 88.730  118.011 93.439  1.00 64.41  ? 405 ARG A HD2  1 
ATOM 6003 H HD3  . ARG A 1 405 ? 89.754  117.646 94.594  1.00 65.98  ? 405 ARG A HD3  1 
ATOM 6004 H HE   . ARG A 1 405 ? 89.851  119.789 95.170  1.00 67.76  ? 405 ARG A HE   1 
ATOM 6005 H HH11 . ARG A 1 405 ? 87.667  119.508 92.671  1.00 61.12  ? 405 ARG A HH11 1 
ATOM 6006 H HH12 . ARG A 1 405 ? 87.056  120.849 92.873  1.00 61.48  ? 405 ARG A HH12 1 
ATOM 6007 H HH21 . ARG A 1 405 ? 88.896  121.799 95.424  1.00 74.29  ? 405 ARG A HH21 1 
ATOM 6008 H HH22 . ARG A 1 405 ? 87.790  122.227 94.523  1.00 76.20  ? 405 ARG A HH22 1 
ATOM 6009 N N    . ARG A 1 406 ? 91.324  117.999 88.653  1.00 49.00  ? 406 ARG A N    1 
ATOM 6010 C CA   . ARG A 1 406 ? 91.884  117.006 87.739  1.00 43.18  ? 406 ARG A CA   1 
ATOM 6011 C C    . ARG A 1 406 ? 93.189  117.471 87.107  1.00 39.18  ? 406 ARG A C    1 
ATOM 6012 O O    . ARG A 1 406 ? 94.168  116.701 87.120  1.00 37.12  ? 406 ARG A O    1 
ATOM 6013 C CB   . ARG A 1 406 ? 90.817  116.655 86.691  1.00 41.46  ? 406 ARG A CB   1 
ATOM 6014 C CG   . ARG A 1 406 ? 91.304  116.296 85.287  1.00 38.79  ? 406 ARG A CG   1 
ATOM 6015 C CD   . ARG A 1 406 ? 90.193  116.536 84.279  1.00 35.83  ? 406 ARG A CD   1 
ATOM 6016 N NE   . ARG A 1 406 ? 90.447  115.890 82.998  1.00 38.15  ? 406 ARG A NE   1 
ATOM 6017 C CZ   . ARG A 1 406 ? 89.635  115.961 81.952  1.00 41.92  ? 406 ARG A CZ   1 
ATOM 6018 N NH1  . ARG A 1 406 ? 88.503  116.645 81.999  1.00 40.10  ? 406 ARG A NH1  1 
ATOM 6019 N NH2  . ARG A 1 406 ? 89.967  115.331 80.829  1.00 42.62  ? 406 ARG A NH2  1 
ATOM 6020 H H    . ARG A 1 406 ? 90.553  118.302 88.421  1.00 47.66  ? 406 ARG A H    1 
ATOM 6021 H HA   . ARG A 1 406 ? 92.076  116.199 88.242  1.00 43.96  ? 406 ARG A HA   1 
ATOM 6022 H HB2  . ARG A 1 406 ? 90.314  115.895 87.020  1.00 41.59  ? 406 ARG A HB2  1 
ATOM 6023 H HB3  . ARG A 1 406 ? 90.220  117.414 86.599  1.00 41.01  ? 406 ARG A HB3  1 
ATOM 6024 H HG2  . ARG A 1 406 ? 92.051  116.850 85.020  1.00 40.37  ? 406 ARG A HG2  1 
ATOM 6025 H HG3  . ARG A 1 406 ? 91.548  115.358 85.258  1.00 37.94  ? 406 ARG A HG3  1 
ATOM 6026 H HD2  . ARG A 1 406 ? 89.361  116.184 84.634  1.00 36.50  ? 406 ARG A HD2  1 
ATOM 6027 H HD3  . ARG A 1 406 ? 90.109  117.489 84.122  1.00 35.67  ? 406 ARG A HD3  1 
ATOM 6028 H HE   . ARG A 1 406 ? 91.157  115.412 82.922  1.00 38.56  ? 406 ARG A HE   1 
ATOM 6029 H HH11 . ARG A 1 406 ? 88.277  117.058 82.719  1.00 38.65  ? 406 ARG A HH11 1 
ATOM 6030 H HH12 . ARG A 1 406 ? 87.992  116.678 81.308  1.00 40.35  ? 406 ARG A HH12 1 
ATOM 6031 H HH21 . ARG A 1 406 ? 90.700  114.883 80.787  1.00 41.50  ? 406 ARG A HH21 1 
ATOM 6032 H HH22 . ARG A 1 406 ? 89.447  115.371 80.144  1.00 41.07  ? 406 ARG A HH22 1 
ATOM 6033 N N    . PRO A 1 407 ? 93.274  118.667 86.514  1.00 39.95  ? 407 PRO A N    1 
ATOM 6034 C CA   . PRO A 1 407 ? 94.568  119.106 85.969  1.00 33.22  ? 407 PRO A CA   1 
ATOM 6035 C C    . PRO A 1 407 ? 95.668  119.146 87.010  1.00 32.74  ? 407 PRO A C    1 
ATOM 6036 O O    . PRO A 1 407 ? 96.796  118.733 86.725  1.00 40.61  ? 407 PRO A O    1 
ATOM 6037 C CB   . PRO A 1 407 ? 94.258  120.503 85.415  1.00 23.74  ? 407 PRO A CB   1 
ATOM 6038 C CG   . PRO A 1 407 ? 92.807  120.487 85.128  1.00 34.54  ? 407 PRO A CG   1 
ATOM 6039 C CD   . PRO A 1 407 ? 92.183  119.590 86.158  1.00 45.28  ? 407 PRO A CD   1 
ATOM 6040 H HA   . PRO A 1 407 ? 94.838  118.527 85.239  1.00 36.11  ? 407 PRO A HA   1 
ATOM 6041 H HB2  . PRO A 1 407 ? 94.470  121.175 86.082  1.00 31.55  ? 407 PRO A HB2  1 
ATOM 6042 H HB3  . PRO A 1 407 ? 94.767  120.653 84.603  1.00 27.22  ? 407 PRO A HB3  1 
ATOM 6043 H HG2  . PRO A 1 407 ? 92.453  121.387 85.201  1.00 36.91  ? 407 PRO A HG2  1 
ATOM 6044 H HG3  . PRO A 1 407 ? 92.658  120.135 84.237  1.00 35.50  ? 407 PRO A HG3  1 
ATOM 6045 H HD2  . PRO A 1 407 ? 91.904  120.103 86.931  1.00 44.60  ? 407 PRO A HD2  1 
ATOM 6046 H HD3  . PRO A 1 407 ? 91.441  119.106 85.764  1.00 42.50  ? 407 PRO A HD3  1 
ATOM 6047 N N    . THR A 1 408 ? 95.368  119.623 88.219  1.00 32.08  ? 408 THR A N    1 
ATOM 6048 C CA   . THR A 1 408 ? 96.393  119.695 89.255  1.00 35.09  ? 408 THR A CA   1 
ATOM 6049 C C    . THR A 1 408 ? 96.883  118.304 89.631  1.00 36.76  ? 408 THR A C    1 
ATOM 6050 O O    . THR A 1 408 ? 98.090  118.066 89.740  1.00 43.47  ? 408 THR A O    1 
ATOM 6051 C CB   . THR A 1 408 ? 95.848  120.425 90.484  1.00 46.46  ? 408 THR A CB   1 
ATOM 6052 O OG1  . THR A 1 408 ? 95.768  121.829 90.212  1.00 60.65  ? 408 THR A OG1  1 
ATOM 6053 C CG2  . THR A 1 408 ? 96.750  120.199 91.689  1.00 39.39  ? 408 THR A CG2  1 
ATOM 6054 H H    . THR A 1 408 ? 94.593  119.906 88.460  1.00 38.74  ? 408 THR A H    1 
ATOM 6055 H HA   . THR A 1 408 ? 97.150  120.199 88.917  1.00 38.78  ? 408 THR A HA   1 
ATOM 6056 H HB   . THR A 1 408 ? 94.964  120.086 90.694  1.00 45.88  ? 408 THR A HB   1 
ATOM 6057 H HG1  . THR A 1 408 ? 95.460  122.234 90.880  1.00 57.82  ? 408 THR A HG1  1 
ATOM 6058 H HG21 . THR A 1 408 ? 96.576  119.328 92.078  1.00 39.23  ? 408 THR A HG21 1 
ATOM 6059 H HG22 . THR A 1 408 ? 97.682  120.248 91.423  1.00 42.91  ? 408 THR A HG22 1 
ATOM 6060 H HG23 . THR A 1 408 ? 96.578  120.879 92.360  1.00 46.31  ? 408 THR A HG23 1 
ATOM 6061 N N    . GLN A 1 409 ? 95.954  117.365 89.823  1.00 39.91  ? 409 GLN A N    1 
ATOM 6062 C CA   . GLN A 1 409 ? 96.340  116.003 90.176  1.00 44.71  ? 409 GLN A CA   1 
ATOM 6063 C C    . GLN A 1 409 ? 97.216  115.392 89.090  1.00 45.21  ? 409 GLN A C    1 
ATOM 6064 O O    . GLN A 1 409 ? 98.300  114.855 89.368  1.00 45.73  ? 409 GLN A O    1 
ATOM 6065 C CB   . GLN A 1 409 ? 95.083  115.159 90.403  1.00 38.98  ? 409 GLN A CB   1 
ATOM 6066 C CG   . GLN A 1 409 ? 95.318  113.662 90.542  1.00 43.26  ? 409 GLN A CG   1 
ATOM 6067 C CD   . GLN A 1 409 ? 96.030  113.305 91.827  1.00 53.25  ? 409 GLN A CD   1 
ATOM 6068 O OE1  . GLN A 1 409 ? 95.674  113.789 92.901  1.00 58.04  ? 409 GLN A OE1  1 
ATOM 6069 N NE2  . GLN A 1 409 ? 97.041  112.452 91.726  1.00 53.22  ? 409 GLN A NE2  1 
ATOM 6070 H H    . GLN A 1 409 ? 95.106  117.491 89.756  1.00 41.37  ? 409 GLN A H    1 
ATOM 6071 H HA   . GLN A 1 409 ? 96.848  116.019 91.002  1.00 44.47  ? 409 GLN A HA   1 
ATOM 6072 H HB2  . GLN A 1 409 ? 94.651  115.462 91.216  1.00 42.19  ? 409 GLN A HB2  1 
ATOM 6073 H HB3  . GLN A 1 409 ? 94.485  115.290 89.650  1.00 41.06  ? 409 GLN A HB3  1 
ATOM 6074 H HG2  . GLN A 1 409 ? 94.458  113.213 90.548  1.00 45.30  ? 409 GLN A HG2  1 
ATOM 6075 H HG3  . GLN A 1 409 ? 95.849  113.337 89.799  1.00 45.90  ? 409 GLN A HG3  1 
ATOM 6076 H HE21 . GLN A 1 409 ? 97.260  112.134 90.958  1.00 50.69  ? 409 GLN A HE21 1 
ATOM 6077 H HE22 . GLN A 1 409 ? 97.477  112.217 92.429  1.00 52.42  ? 409 GLN A HE22 1 
ATOM 6078 N N    . ALA A 1 410 ? 96.761  115.472 87.837  1.00 40.01  ? 410 ALA A N    1 
ATOM 6079 C CA   . ALA A 1 410 ? 97.509  114.866 86.742  1.00 39.72  ? 410 ALA A CA   1 
ATOM 6080 C C    . ALA A 1 410 ? 98.891  115.492 86.614  1.00 39.77  ? 410 ALA A C    1 
ATOM 6081 O O    . ALA A 1 410 ? 99.897  114.783 86.487  1.00 38.81  ? 410 ALA A O    1 
ATOM 6082 C CB   . ALA A 1 410 ? 96.728  115.007 85.436  1.00 37.33  ? 410 ALA A CB   1 
ATOM 6083 H H    . ALA A 1 410 ? 96.035  115.867 87.600  1.00 39.66  ? 410 ALA A H    1 
ATOM 6084 H HA   . ALA A 1 410 ? 97.623  113.920 86.923  1.00 39.72  ? 410 ALA A HA   1 
ATOM 6085 H HB1  . ALA A 1 410 ? 95.876  114.554 85.529  1.00 36.86  ? 410 ALA A HB1  1 
ATOM 6086 H HB2  . ALA A 1 410 ? 96.584  115.949 85.254  1.00 38.01  ? 410 ALA A HB2  1 
ATOM 6087 H HB3  . ALA A 1 410 ? 97.240  114.605 84.717  1.00 37.50  ? 410 ALA A HB3  1 
ATOM 6088 N N    . ALA A 1 411 ? 98.962  116.825 86.651  1.00 35.14  ? 411 ALA A N    1 
ATOM 6089 C CA   . ALA A 1 411 ? 100.242 117.501 86.495  1.00 32.85  ? 411 ALA A CA   1 
ATOM 6090 C C    . ALA A 1 411 ? 101.192 117.152 87.630  1.00 32.26  ? 411 ALA A C    1 
ATOM 6091 O O    . ALA A 1 411 ? 102.370 116.871 87.392  1.00 37.07  ? 411 ALA A O    1 
ATOM 6092 C CB   . ALA A 1 411 ? 100.031 119.012 86.423  1.00 31.69  ? 411 ALA A CB   1 
ATOM 6093 H H    . ALA A 1 411 ? 98.290  117.350 86.764  1.00 37.70  ? 411 ALA A H    1 
ATOM 6094 H HA   . ALA A 1 411 ? 100.650 117.215 85.663  1.00 34.75  ? 411 ALA A HA   1 
ATOM 6095 H HB1  . ALA A 1 411 ? 99.604  119.310 87.241  1.00 34.60  ? 411 ALA A HB1  1 
ATOM 6096 H HB2  . ALA A 1 411 ? 100.893 119.446 86.322  1.00 31.56  ? 411 ALA A HB2  1 
ATOM 6097 H HB3  . ALA A 1 411 ? 99.466  119.216 85.661  1.00 33.89  ? 411 ALA A HB3  1 
ATOM 6098 N N    . SER A 1 412 ? 100.704 117.163 88.871  1.00 28.45  ? 412 SER A N    1 
ATOM 6099 C CA   . SER A 1 412 ? 101.573 116.850 90.000  1.00 32.74  ? 412 SER A CA   1 
ATOM 6100 C C    . SER A 1 412 ? 102.127 115.437 89.885  1.00 36.38  ? 412 SER A C    1 
ATOM 6101 O O    . SER A 1 412 ? 103.336 115.216 90.034  1.00 37.47  ? 412 SER A O    1 
ATOM 6102 C CB   . SER A 1 412 ? 100.805 117.025 91.309  1.00 36.99  ? 412 SER A CB   1 
ATOM 6103 O OG   . SER A 1 412 ? 100.195 115.812 91.706  1.00 40.79  ? 412 SER A OG   1 
ATOM 6104 H H    . SER A 1 412 ? 99.891  117.345 89.081  1.00 34.11  ? 412 SER A H    1 
ATOM 6105 H HA   . SER A 1 412 ? 102.322 117.467 90.005  1.00 34.18  ? 412 SER A HA   1 
ATOM 6106 H HB2  . SER A 1 412 ? 101.423 117.308 92.002  1.00 36.46  ? 412 SER A HB2  1 
ATOM 6107 H HB3  . SER A 1 412 ? 100.118 117.697 91.184  1.00 37.70  ? 412 SER A HB3  1 
ATOM 6108 H HG   . SER A 1 412 ? 99.630  115.573 91.132  1.00 40.77  ? 412 SER A HG   1 
ATOM 6109 N N    . LEU A 1 413 ? 101.258 114.463 89.598  1.00 37.41  ? 413 LEU A N    1 
ATOM 6110 C CA   . LEU A 1 413 ? 101.719 113.081 89.517  1.00 38.50  ? 413 LEU A CA   1 
ATOM 6111 C C    . LEU A 1 413 ? 102.711 112.901 88.372  1.00 36.12  ? 413 LEU A C    1 
ATOM 6112 O O    . LEU A 1 413 ? 103.775 112.289 88.544  1.00 36.33  ? 413 LEU A O    1 
ATOM 6113 C CB   . LEU A 1 413 ? 100.521 112.144 89.352  1.00 38.34  ? 413 LEU A CB   1 
ATOM 6114 C CG   . LEU A 1 413 ? 100.619 110.734 89.946  1.00 41.61  ? 413 LEU A CG   1 
ATOM 6115 C CD1  . LEU A 1 413 ? 101.141 110.747 91.376  1.00 43.39  ? 413 LEU A CD1  1 
ATOM 6116 C CD2  . LEU A 1 413 ? 99.268  110.041 89.885  1.00 43.79  ? 413 LEU A CD2  1 
ATOM 6117 H H    . LEU A 1 413 ? 100.419 114.575 89.449  1.00 37.98  ? 413 LEU A H    1 
ATOM 6118 H HA   . LEU A 1 413 ? 102.178 112.862 90.341  1.00 38.70  ? 413 LEU A HA   1 
ATOM 6119 H HB2  . LEU A 1 413 ? 99.753  112.568 89.765  1.00 39.77  ? 413 LEU A HB2  1 
ATOM 6120 H HB3  . LEU A 1 413 ? 100.352 112.039 88.403  1.00 38.60  ? 413 LEU A HB3  1 
ATOM 6121 H HG   . LEU A 1 413 ? 101.240 110.215 89.411  1.00 41.46  ? 413 LEU A HG   1 
ATOM 6122 H HD11 . LEU A 1 413 ? 102.101 110.883 91.360  1.00 41.90  ? 413 LEU A HD11 1 
ATOM 6123 H HD12 . LEU A 1 413 ? 100.712 111.469 91.862  1.00 41.84  ? 413 LEU A HD12 1 
ATOM 6124 H HD13 . LEU A 1 413 ? 100.937 109.897 91.796  1.00 43.22  ? 413 LEU A HD13 1 
ATOM 6125 H HD21 . LEU A 1 413 ? 99.018  109.915 88.957  1.00 44.87  ? 413 LEU A HD21 1 
ATOM 6126 H HD22 . LEU A 1 413 ? 99.336  109.182 90.330  1.00 44.39  ? 413 LEU A HD22 1 
ATOM 6127 H HD23 . LEU A 1 413 ? 98.609  110.593 90.335  1.00 42.50  ? 413 LEU A HD23 1 
ATOM 6128 N N    . VAL A 1 414 ? 102.388 113.449 87.196  1.00 32.61  ? 414 VAL A N    1 
ATOM 6129 C CA   . VAL A 1 414 ? 103.259 113.285 86.036  1.00 29.83  ? 414 VAL A CA   1 
ATOM 6130 C C    . VAL A 1 414 ? 104.608 113.938 86.290  1.00 33.08  ? 414 VAL A C    1 
ATOM 6131 O O    . VAL A 1 414 ? 105.657 113.366 85.975  1.00 34.29  ? 414 VAL A O    1 
ATOM 6132 C CB   . VAL A 1 414 ? 102.584 113.858 84.775  1.00 26.04  ? 414 VAL A CB   1 
ATOM 6133 C CG1  . VAL A 1 414 ? 103.621 114.149 83.696  1.00 27.82  ? 414 VAL A CG1  1 
ATOM 6134 C CG2  . VAL A 1 414 ? 101.526 112.902 84.256  1.00 32.96  ? 414 VAL A CG2  1 
ATOM 6135 H H    . VAL A 1 414 ? 101.681 113.915 87.049  1.00 33.88  ? 414 VAL A H    1 
ATOM 6136 H HA   . VAL A 1 414 ? 103.413 112.338 85.892  1.00 31.93  ? 414 VAL A HA   1 
ATOM 6137 H HB   . VAL A 1 414 ? 102.147 114.693 85.003  1.00 30.39  ? 414 VAL A HB   1 
ATOM 6138 H HG11 . VAL A 1 414 ? 103.166 114.248 82.845  1.00 28.38  ? 414 VAL A HG11 1 
ATOM 6139 H HG12 . VAL A 1 414 ? 104.089 114.970 83.912  1.00 29.99  ? 414 VAL A HG12 1 
ATOM 6140 H HG13 . VAL A 1 414 ? 104.246 113.409 83.648  1.00 28.03  ? 414 VAL A HG13 1 
ATOM 6141 H HG21 . VAL A 1 414 ? 101.368 112.209 84.916  1.00 33.37  ? 414 VAL A HG21 1 
ATOM 6142 H HG22 . VAL A 1 414 ? 100.708 113.399 84.095  1.00 34.25  ? 414 VAL A HG22 1 
ATOM 6143 H HG23 . VAL A 1 414 ? 101.838 112.506 83.428  1.00 31.29  ? 414 VAL A HG23 1 
ATOM 6144 N N    . LEU A 1 415 ? 104.609 115.149 86.852  1.00 36.26  ? 415 LEU A N    1 
ATOM 6145 C CA   . LEU A 1 415 ? 105.868 115.841 87.095  1.00 29.93  ? 415 LEU A CA   1 
ATOM 6146 C C    . LEU A 1 415 ? 106.717 115.109 88.124  1.00 32.01  ? 415 LEU A C    1 
ATOM 6147 O O    . LEU A 1 415 ? 107.935 114.991 87.953  1.00 37.40  ? 415 LEU A O    1 
ATOM 6148 C CB   . LEU A 1 415 ? 105.604 117.275 87.550  1.00 24.83  ? 415 LEU A CB   1 
ATOM 6149 C CG   . LEU A 1 415 ? 105.052 118.265 86.520  1.00 33.47  ? 415 LEU A CG   1 
ATOM 6150 C CD1  . LEU A 1 415 ? 105.192 119.683 87.053  1.00 43.18  ? 415 LEU A CD1  1 
ATOM 6151 C CD2  . LEU A 1 415 ? 105.760 118.134 85.174  1.00 32.61  ? 415 LEU A CD2  1 
ATOM 6152 H H    . LEU A 1 415 ? 103.905 115.581 87.096  1.00 34.87  ? 415 LEU A H    1 
ATOM 6153 H HA   . LEU A 1 415 ? 106.375 115.862 86.270  1.00 31.53  ? 415 LEU A HA   1 
ATOM 6154 H HB2  . LEU A 1 415 ? 104.969 117.243 88.282  1.00 30.39  ? 415 LEU A HB2  1 
ATOM 6155 H HB3  . LEU A 1 415 ? 106.441 117.640 87.873  1.00 28.09  ? 415 LEU A HB3  1 
ATOM 6156 H HG   . LEU A 1 415 ? 104.109 118.090 86.382  1.00 33.26  ? 415 LEU A HG   1 
ATOM 6157 H HD11 . LEU A 1 415 ? 104.850 120.304 86.391  1.00 39.58  ? 415 LEU A HD11 1 
ATOM 6158 H HD12 . LEU A 1 415 ? 104.683 119.762 87.876  1.00 40.03  ? 415 LEU A HD12 1 
ATOM 6159 H HD13 . LEU A 1 415 ? 106.129 119.865 87.226  1.00 39.22  ? 415 LEU A HD13 1 
ATOM 6160 H HD21 . LEU A 1 415 ? 105.463 117.323 84.733  1.00 30.51  ? 415 LEU A HD21 1 
ATOM 6161 H HD22 . LEU A 1 415 ? 105.546 118.905 84.625  1.00 34.32  ? 415 LEU A HD22 1 
ATOM 6162 H HD23 . LEU A 1 415 ? 106.718 118.096 85.324  1.00 34.00  ? 415 LEU A HD23 1 
ATOM 6163 N N    . ALA A 1 416 ? 106.104 114.620 89.204  1.00 31.56  ? 416 ALA A N    1 
ATOM 6164 C CA   . ALA A 1 416 ? 106.881 113.889 90.199  1.00 33.85  ? 416 ALA A CA   1 
ATOM 6165 C C    . ALA A 1 416 ? 107.500 112.638 89.586  1.00 36.32  ? 416 ALA A C    1 
ATOM 6166 O O    . ALA A 1 416 ? 108.695 112.363 89.770  1.00 42.36  ? 416 ALA A O    1 
ATOM 6167 C CB   . ALA A 1 416 ? 105.999 113.534 91.393  1.00 34.71  ? 416 ALA A CB   1 
ATOM 6168 H H    . ALA A 1 416 ? 105.264 114.692 89.378  1.00 33.48  ? 416 ALA A H    1 
ATOM 6169 H HA   . ALA A 1 416 ? 107.603 114.450 90.518  1.00 35.14  ? 416 ALA A HA   1 
ATOM 6170 H HB1  . ALA A 1 416 ? 106.567 113.253 92.125  1.00 34.17  ? 416 ALA A HB1  1 
ATOM 6171 H HB2  . ALA A 1 416 ? 105.495 114.319 91.655  1.00 34.69  ? 416 ALA A HB2  1 
ATOM 6172 H HB3  . ALA A 1 416 ? 105.392 112.822 91.136  1.00 34.27  ? 416 ALA A HB3  1 
ATOM 6173 N N    . GLY A 1 417 ? 106.704 111.877 88.830  1.00 39.27  ? 417 GLY A N    1 
ATOM 6174 C CA   . GLY A 1 417 ? 107.244 110.700 88.171  1.00 39.00  ? 417 GLY A CA   1 
ATOM 6175 C C    . GLY A 1 417 ? 108.370 111.036 87.212  1.00 36.04  ? 417 GLY A C    1 
ATOM 6176 O O    . GLY A 1 417 ? 109.376 110.325 87.144  1.00 40.05  ? 417 GLY A O    1 
ATOM 6177 H H    . GLY A 1 417 ? 105.867 112.021 88.686  1.00 37.54  ? 417 GLY A H    1 
ATOM 6178 H HA2  . GLY A 1 417 ? 107.580 110.076 88.833  1.00 36.99  ? 417 GLY A HA2  1 
ATOM 6179 H HA3  . GLY A 1 417 ? 106.540 110.264 87.668  1.00 38.09  ? 417 GLY A HA3  1 
ATOM 6180 N N    . LEU A 1 418 ? 108.216 112.123 86.453  1.00 31.31  ? 418 LEU A N    1 
ATOM 6181 C CA   . LEU A 1 418 ? 109.219 112.470 85.454  1.00 31.56  ? 418 LEU A CA   1 
ATOM 6182 C C    . LEU A 1 418 ? 110.517 112.931 86.105  1.00 35.96  ? 418 LEU A C    1 
ATOM 6183 O O    . LEU A 1 418 ? 111.605 112.595 85.626  1.00 39.41  ? 418 LEU A O    1 
ATOM 6184 C CB   . LEU A 1 418 ? 108.670 113.543 84.516  1.00 32.19  ? 418 LEU A CB   1 
ATOM 6185 C CG   . LEU A 1 418 ? 109.603 114.009 83.397  1.00 36.82  ? 418 LEU A CG   1 
ATOM 6186 C CD1  . LEU A 1 418 ? 110.218 112.828 82.661  1.00 39.14  ? 418 LEU A CD1  1 
ATOM 6187 C CD2  . LEU A 1 418 ? 108.853 114.905 82.429  1.00 45.42  ? 418 LEU A CD2  1 
ATOM 6188 H H    . LEU A 1 418 ? 107.551 112.665 86.498  1.00 33.74  ? 418 LEU A H    1 
ATOM 6189 H HA   . LEU A 1 418 ? 109.418 111.680 84.928  1.00 33.40  ? 418 LEU A HA   1 
ATOM 6190 H HB2  . LEU A 1 418 ? 107.867 113.196 84.096  1.00 32.12  ? 418 LEU A HB2  1 
ATOM 6191 H HB3  . LEU A 1 418 ? 108.445 114.324 85.047  1.00 35.24  ? 418 LEU A HB3  1 
ATOM 6192 H HG   . LEU A 1 418 ? 110.325 114.528 83.785  1.00 37.12  ? 418 LEU A HG   1 
ATOM 6193 H HD11 . LEU A 1 418 ? 109.514 112.207 82.417  1.00 38.40  ? 418 LEU A HD11 1 
ATOM 6194 H HD12 . LEU A 1 418 ? 110.665 113.152 81.864  1.00 41.15  ? 418 LEU A HD12 1 
ATOM 6195 H HD13 . LEU A 1 418 ? 110.858 112.389 83.243  1.00 36.93  ? 418 LEU A HD13 1 
ATOM 6196 H HD21 . LEU A 1 418 ? 108.494 115.664 82.914  1.00 42.07  ? 418 LEU A HD21 1 
ATOM 6197 H HD22 . LEU A 1 418 ? 109.467 115.211 81.743  1.00 44.69  ? 418 LEU A HD22 1 
ATOM 6198 H HD23 . LEU A 1 418 ? 108.132 114.397 82.026  1.00 41.73  ? 418 LEU A HD23 1 
ATOM 6199 N N    . CYS A 1 419 ? 110.433 113.703 87.193  1.00 40.80  ? 419 CYS A N    1 
ATOM 6200 C CA   . CYS A 1 419 ? 111.647 114.058 87.924  1.00 40.25  ? 419 CYS A CA   1 
ATOM 6201 C C    . CYS A 1 419 ? 112.326 112.820 88.497  1.00 40.15  ? 419 CYS A C    1 
ATOM 6202 O O    . CYS A 1 419 ? 113.557 112.696 88.438  1.00 39.89  ? 419 CYS A O    1 
ATOM 6203 C CB   . CYS A 1 419 ? 111.338 115.061 89.037  1.00 41.32  ? 419 CYS A CB   1 
ATOM 6204 S SG   . CYS A 1 419 ? 110.373 116.511 88.534  1.00 54.04  ? 419 CYS A SG   1 
ATOM 6205 H H    . CYS A 1 419 ? 109.705 114.024 87.519  1.00 39.13  ? 419 CYS A H    1 
ATOM 6206 H HA   . CYS A 1 419 ? 112.269 114.481 87.310  1.00 39.29  ? 419 CYS A HA   1 
ATOM 6207 H HB2  . CYS A 1 419 ? 110.839 114.601 89.730  1.00 40.02  ? 419 CYS A HB2  1 
ATOM 6208 H HB3  . CYS A 1 419 ? 112.176 115.382 89.406  1.00 42.05  ? 419 CYS A HB3  1 
ATOM 6209 H HG   . CYS A 1 419 ? 109.737 116.282 87.543  1.00 43.16  ? 419 CYS A HG   1 
ATOM 6210 N N    . ILE A 1 420 ? 111.547 111.888 89.055  1.00 41.50  ? 420 ILE A N    1 
ATOM 6211 C CA   . ILE A 1 420 ? 112.152 110.666 89.577  1.00 41.34  ? 420 ILE A CA   1 
ATOM 6212 C C    . ILE A 1 420 ? 112.873 109.916 88.465  1.00 40.64  ? 420 ILE A C    1 
ATOM 6213 O O    . ILE A 1 420 ? 114.000 109.439 88.646  1.00 38.36  ? 420 ILE A O    1 
ATOM 6214 C CB   . ILE A 1 420 ? 111.091 109.781 90.255  1.00 48.98  ? 420 ILE A CB   1 
ATOM 6215 C CG1  . ILE A 1 420 ? 110.640 110.406 91.576  1.00 47.19  ? 420 ILE A CG1  1 
ATOM 6216 C CG2  . ILE A 1 420 ? 111.645 108.385 90.499  1.00 48.27  ? 420 ILE A CG2  1 
ATOM 6217 C CD1  . ILE A 1 420 ? 109.250 109.989 92.002  1.00 47.80  ? 420 ILE A CD1  1 
ATOM 6218 H H    . ILE A 1 420 ? 110.692 111.934 89.140  1.00 41.18  ? 420 ILE A H    1 
ATOM 6219 H HA   . ILE A 1 420 ? 112.812 110.906 90.246  1.00 41.24  ? 420 ILE A HA   1 
ATOM 6220 H HB   . ILE A 1 420 ? 110.323 109.712 89.667  1.00 46.23  ? 420 ILE A HB   1 
ATOM 6221 H HG12 . ILE A 1 420 ? 111.260 110.143 92.274  1.00 46.47  ? 420 ILE A HG12 1 
ATOM 6222 H HG13 . ILE A 1 420 ? 110.645 111.371 91.483  1.00 44.40  ? 420 ILE A HG13 1 
ATOM 6223 H HG21 . ILE A 1 420 ? 111.072 107.927 91.132  1.00 49.06  ? 420 ILE A HG21 1 
ATOM 6224 H HG22 . ILE A 1 420 ? 111.663 107.895 89.662  1.00 46.69  ? 420 ILE A HG22 1 
ATOM 6225 H HG23 . ILE A 1 420 ? 112.542 108.460 90.861  1.00 47.05  ? 420 ILE A HG23 1 
ATOM 6226 H HD11 . ILE A 1 420 ? 109.119 110.237 92.931  1.00 48.28  ? 420 ILE A HD11 1 
ATOM 6227 H HD12 . ILE A 1 420 ? 108.598 110.439 91.444  1.00 43.82  ? 420 ILE A HD12 1 
ATOM 6228 H HD13 . ILE A 1 420 ? 109.165 109.028 91.903  1.00 48.23  ? 420 ILE A HD13 1 
ATOM 6229 N N    . LEU A 1 421 ? 112.236 109.795 87.299  1.00 45.30  ? 421 LEU A N    1 
ATOM 6230 C CA   . LEU A 1 421 ? 112.867 109.097 86.183  1.00 44.74  ? 421 LEU A CA   1 
ATOM 6231 C C    . LEU A 1 421 ? 114.135 109.814 85.735  1.00 47.67  ? 421 LEU A C    1 
ATOM 6232 O O    . LEU A 1 421 ? 115.167 109.176 85.495  1.00 51.70  ? 421 LEU A O    1 
ATOM 6233 C CB   . LEU A 1 421 ? 111.873 108.967 85.026  1.00 39.02  ? 421 LEU A CB   1 
ATOM 6234 C CG   . LEU A 1 421 ? 112.344 108.401 83.679  1.00 44.53  ? 421 LEU A CG   1 
ATOM 6235 C CD1  . LEU A 1 421 ? 113.029 109.458 82.813  1.00 40.94  ? 421 LEU A CD1  1 
ATOM 6236 C CD2  . LEU A 1 421 ? 113.254 107.197 83.878  1.00 48.24  ? 421 LEU A CD2  1 
ATOM 6237 H H    . LEU A 1 421 ? 111.450 110.103 87.131  1.00 43.19  ? 421 LEU A H    1 
ATOM 6238 H HA   . LEU A 1 421 ? 113.114 108.203 86.469  1.00 44.01  ? 421 LEU A HA   1 
ATOM 6239 H HB2  . LEU A 1 421 ? 111.150 108.394 85.326  1.00 39.15  ? 421 LEU A HB2  1 
ATOM 6240 H HB3  . LEU A 1 421 ? 111.516 109.850 84.846  1.00 40.68  ? 421 LEU A HB3  1 
ATOM 6241 H HG   . LEU A 1 421 ? 111.564 108.093 83.191  1.00 45.18  ? 421 LEU A HG   1 
ATOM 6242 H HD11 . LEU A 1 421 ? 113.101 109.120 81.907  1.00 43.96  ? 421 LEU A HD11 1 
ATOM 6243 H HD12 . LEU A 1 421 ? 112.493 110.266 82.820  1.00 39.40  ? 421 LEU A HD12 1 
ATOM 6244 H HD13 . LEU A 1 421 ? 113.912 109.642 83.164  1.00 42.01  ? 421 LEU A HD13 1 
ATOM 6245 H HD21 . LEU A 1 421 ? 113.469 106.821 83.010  1.00 47.53  ? 421 LEU A HD21 1 
ATOM 6246 H HD22 . LEU A 1 421 ? 114.066 107.477 84.324  1.00 46.58  ? 421 LEU A HD22 1 
ATOM 6247 H HD23 . LEU A 1 421 ? 112.790 106.538 84.417  1.00 46.10  ? 421 LEU A HD23 1 
ATOM 6248 N N    . ALA A 1 422 ? 114.082 111.143 85.625  1.00 49.15  ? 422 ALA A N    1 
ATOM 6249 C CA   . ALA A 1 422 ? 115.243 111.898 85.169  1.00 42.22  ? 422 ALA A CA   1 
ATOM 6250 C C    . ALA A 1 422 ? 116.398 111.806 86.156  1.00 41.23  ? 422 ALA A C    1 
ATOM 6251 O O    . ALA A 1 422 ? 117.563 111.923 85.759  1.00 43.76  ? 422 ALA A O    1 
ATOM 6252 C CB   . ALA A 1 422 ? 114.858 113.359 84.943  1.00 41.25  ? 422 ALA A CB   1 
ATOM 6253 H H    . ALA A 1 422 ? 113.393 111.624 85.808  1.00 44.87  ? 422 ALA A H    1 
ATOM 6254 H HA   . ALA A 1 422 ? 115.544 111.533 84.322  1.00 43.04  ? 422 ALA A HA   1 
ATOM 6255 H HB1  . ALA A 1 422 ? 115.640 113.848 84.641  1.00 40.91  ? 422 ALA A HB1  1 
ATOM 6256 H HB2  . ALA A 1 422 ? 114.160 113.402 84.271  1.00 43.44  ? 422 ALA A HB2  1 
ATOM 6257 H HB3  . ALA A 1 422 ? 114.538 113.732 85.779  1.00 41.09  ? 422 ALA A HB3  1 
ATOM 6258 N N    . ASN A 1 423 ? 116.100 111.605 87.441  1.00 46.34  ? 423 ASN A N    1 
ATOM 6259 C CA   . ASN A 1 423 ? 117.167 111.504 88.433  1.00 50.32  ? 423 ASN A CA   1 
ATOM 6260 C C    . ASN A 1 423 ? 118.157 110.401 88.073  1.00 48.47  ? 423 ASN A C    1 
ATOM 6261 O O    . ASN A 1 423 ? 119.358 110.525 88.339  1.00 48.87  ? 423 ASN A O    1 
ATOM 6262 C CB   . ASN A 1 423 ? 116.570 111.258 89.819  1.00 49.79  ? 423 ASN A CB   1 
ATOM 6263 C CG   . ASN A 1 423 ? 117.549 110.599 90.770  1.00 49.95  ? 423 ASN A CG   1 
ATOM 6264 O OD1  . ASN A 1 423 ? 117.792 109.395 90.694  1.00 49.98  ? 423 ASN A OD1  1 
ATOM 6265 N ND2  . ASN A 1 423 ? 118.115 111.386 91.676  1.00 49.55  ? 423 ASN A ND2  1 
ATOM 6266 H H    . ASN A 1 423 ? 115.305 111.524 87.759  1.00 45.04  ? 423 ASN A H    1 
ATOM 6267 H HA   . ASN A 1 423 ? 117.653 112.343 88.460  1.00 48.60  ? 423 ASN A HA   1 
ATOM 6268 H HB2  . ASN A 1 423 ? 116.305 112.108 90.204  1.00 48.00  ? 423 ASN A HB2  1 
ATOM 6269 H HB3  . ASN A 1 423 ? 115.800 110.677 89.733  1.00 48.16  ? 423 ASN A HB3  1 
ATOM 6270 H HD21 . ASN A 1 423 ? 118.677 111.058 92.239  1.00 52.25  ? 423 ASN A HD21 1 
ATOM 6271 H HD22 . ASN A 1 423 ? 117.921 112.223 91.700  1.00 49.42  ? 423 ASN A HD22 1 
ATOM 6272 N N    . THR A 1 424 ? 117.673 109.311 87.473  1.00 49.95  ? 424 THR A N    1 
ATOM 6273 C CA   . THR A 1 424 ? 118.550 108.184 87.165  1.00 52.96  ? 424 THR A CA   1 
ATOM 6274 C C    . THR A 1 424 ? 119.441 108.475 85.964  1.00 56.10  ? 424 THR A C    1 
ATOM 6275 O O    . THR A 1 424 ? 120.624 108.113 85.961  1.00 58.79  ? 424 THR A O    1 
ATOM 6276 C CB   . THR A 1 424 ? 117.718 106.928 86.910  1.00 53.13  ? 424 THR A CB   1 
ATOM 6277 O OG1  . THR A 1 424 ? 117.212 106.428 88.152  1.00 60.88  ? 424 THR A OG1  1 
ATOM 6278 C CG2  . THR A 1 424 ? 118.566 105.850 86.244  1.00 53.88  ? 424 THR A CG2  1 
ATOM 6279 H H    . THR A 1 424 ? 116.853 109.201 87.237  1.00 49.94  ? 424 THR A H    1 
ATOM 6280 H HA   . THR A 1 424 ? 119.124 108.014 87.928  1.00 52.75  ? 424 THR A HA   1 
ATOM 6281 H HB   . THR A 1 424 ? 116.978 107.143 86.322  1.00 51.29  ? 424 THR A HB   1 
ATOM 6282 H HG1  . THR A 1 424 ? 116.735 107.011 88.523  1.00 55.13  ? 424 THR A HG1  1 
ATOM 6283 H HG21 . THR A 1 424 ? 118.148 104.982 86.366  1.00 55.13  ? 424 THR A HG21 1 
ATOM 6284 H HG22 . THR A 1 424 ? 118.650 106.025 85.294  1.00 52.53  ? 424 THR A HG22 1 
ATOM 6285 H HG23 . THR A 1 424 ? 119.450 105.828 86.644  1.00 54.85  ? 424 THR A HG23 1 
ATOM 6286 N N    . LEU A 1 425 ? 118.896 109.122 84.932  1.00 54.98  ? 425 LEU A N    1 
ATOM 6287 C CA   . LEU A 1 425 ? 119.634 109.272 83.682  1.00 52.79  ? 425 LEU A CA   1 
ATOM 6288 C C    . LEU A 1 425 ? 120.910 110.083 83.876  1.00 62.48  ? 425 LEU A C    1 
ATOM 6289 O O    . LEU A 1 425 ? 121.954 109.755 83.299  1.00 63.90  ? 425 LEU A O    1 
ATOM 6290 C CB   . LEU A 1 425 ? 118.745 109.923 82.622  1.00 57.21  ? 425 LEU A CB   1 
ATOM 6291 C CG   . LEU A 1 425 ? 117.893 108.981 81.764  1.00 63.42  ? 425 LEU A CG   1 
ATOM 6292 C CD1  . LEU A 1 425 ? 118.700 108.482 80.572  1.00 66.94  ? 425 LEU A CD1  1 
ATOM 6293 C CD2  . LEU A 1 425 ? 117.337 107.811 82.572  1.00 58.32  ? 425 LEU A CD2  1 
ATOM 6294 H H    . LEU A 1 425 ? 118.113 109.478 84.932  1.00 53.82  ? 425 LEU A H    1 
ATOM 6295 H HA   . LEU A 1 425 ? 119.893 108.395 83.360  1.00 53.45  ? 425 LEU A HA   1 
ATOM 6296 H HB2  . LEU A 1 425 ? 118.136 110.531 83.070  1.00 54.82  ? 425 LEU A HB2  1 
ATOM 6297 H HB3  . LEU A 1 425 ? 119.313 110.425 82.018  1.00 57.29  ? 425 LEU A HB3  1 
ATOM 6298 H HG   . LEU A 1 425 ? 117.138 109.481 81.416  1.00 62.52  ? 425 LEU A HG   1 
ATOM 6299 H HD11 . LEU A 1 425 ? 118.142 107.900 80.033  1.00 66.44  ? 425 LEU A HD11 1 
ATOM 6300 H HD12 . LEU A 1 425 ? 118.990 109.243 80.046  1.00 63.19  ? 425 LEU A HD12 1 
ATOM 6301 H HD13 . LEU A 1 425 ? 119.472 107.992 80.897  1.00 64.60  ? 425 LEU A HD13 1 
ATOM 6302 H HD21 . LEU A 1 425 ? 116.735 107.301 82.007  1.00 59.73  ? 425 LEU A HD21 1 
ATOM 6303 H HD22 . LEU A 1 425 ? 118.067 107.246 82.866  1.00 59.20  ? 425 LEU A HD22 1 
ATOM 6304 H HD23 . LEU A 1 425 ? 116.854 108.158 83.338  1.00 58.20  ? 425 LEU A HD23 1 
ATOM 6305 N N    . VAL A 1 426 ? 120.850 111.142 84.676  1.00 62.57  ? 426 VAL A N    1 
ATOM 6306 C CA   . VAL A 1 426 ? 121.988 112.041 84.848  1.00 55.17  ? 426 VAL A CA   1 
ATOM 6307 C C    . VAL A 1 426 ? 123.138 111.271 85.487  1.00 61.68  ? 426 VAL A C    1 
ATOM 6308 O O    . VAL A 1 426 ? 122.900 110.332 86.260  1.00 65.36  ? 426 VAL A O    1 
ATOM 6309 C CB   . VAL A 1 426 ? 121.607 113.269 85.689  1.00 51.32  ? 426 VAL A CB   1 
ATOM 6310 C CG1  . VAL A 1 426 ? 120.428 113.995 85.059  1.00 57.21  ? 426 VAL A CG1  1 
ATOM 6311 C CG2  . VAL A 1 426 ? 121.293 112.860 87.119  1.00 48.49  ? 426 VAL A CG2  1 
ATOM 6312 H H    . VAL A 1 426 ? 120.157 111.362 85.135  1.00 57.93  ? 426 VAL A H    1 
ATOM 6313 H HA   . VAL A 1 426 ? 122.272 112.350 83.973  1.00 55.79  ? 426 VAL A HA   1 
ATOM 6314 H HB   . VAL A 1 426 ? 122.359 113.882 85.710  1.00 54.03  ? 426 VAL A HB   1 
ATOM 6315 H HG11 . VAL A 1 426 ? 120.274 114.823 85.539  1.00 54.96  ? 426 VAL A HG11 1 
ATOM 6316 H HG12 . VAL A 1 426 ? 120.636 114.183 84.130  1.00 57.89  ? 426 VAL A HG12 1 
ATOM 6317 H HG13 . VAL A 1 426 ? 119.643 113.428 85.114  1.00 56.19  ? 426 VAL A HG13 1 
ATOM 6318 H HG21 . VAL A 1 426 ? 120.833 113.590 87.562  1.00 48.50  ? 426 VAL A HG21 1 
ATOM 6319 H HG22 . VAL A 1 426 ? 120.728 112.073 87.104  1.00 50.84  ? 426 VAL A HG22 1 
ATOM 6320 H HG23 . VAL A 1 426 ? 122.122 112.663 87.582  1.00 51.80  ? 426 VAL A HG23 1 
ATOM 6321 N N    . PRO A 1 427 ? 124.395 111.625 85.200  1.00 72.34  ? 427 PRO A N    1 
ATOM 6322 C CA   . PRO A 1 427 ? 125.520 110.863 85.761  1.00 74.19  ? 427 PRO A CA   1 
ATOM 6323 C C    . PRO A 1 427 ? 125.681 111.082 87.256  1.00 78.35  ? 427 PRO A C    1 
ATOM 6324 O O    . PRO A 1 427 ? 124.913 111.831 87.868  1.00 81.37  ? 427 PRO A O    1 
ATOM 6325 C CB   . PRO A 1 427 ? 126.726 111.395 84.979  1.00 72.97  ? 427 PRO A CB   1 
ATOM 6326 C CG   . PRO A 1 427 ? 126.340 112.768 84.589  1.00 70.04  ? 427 PRO A CG   1 
ATOM 6327 C CD   . PRO A 1 427 ? 124.853 112.742 84.355  1.00 69.58  ? 427 PRO A CD   1 
ATOM 6328 H HA   . PRO A 1 427 ? 125.414 109.916 85.580  1.00 71.34  ? 427 PRO A HA   1 
ATOM 6329 H HB2  . PRO A 1 427 ? 127.510 111.407 85.550  1.00 71.59  ? 427 PRO A HB2  1 
ATOM 6330 H HB3  . PRO A 1 427 ? 126.878 110.846 84.194  1.00 72.81  ? 427 PRO A HB3  1 
ATOM 6331 H HG2  . PRO A 1 427 ? 126.562 113.378 85.309  1.00 68.05  ? 427 PRO A HG2  1 
ATOM 6332 H HG3  . PRO A 1 427 ? 126.807 113.015 83.776  1.00 70.56  ? 427 PRO A HG3  1 
ATOM 6333 H HD2  . PRO A 1 427 ? 124.453 113.575 84.651  1.00 67.13  ? 427 PRO A HD2  1 
ATOM 6334 H HD3  . PRO A 1 427 ? 124.663 112.565 83.421  1.00 68.11  ? 427 PRO A HD3  1 
ATOM 6335 N N    . HIS A 1 428 ? 126.673 110.425 87.855  1.00 82.05  ? 428 HIS A N    1 
ATOM 6336 C CA   . HIS A 1 428 ? 126.949 110.573 89.276  1.00 90.04  ? 428 HIS A CA   1 
ATOM 6337 C C    . HIS A 1 428 ? 127.947 111.684 89.577  1.00 77.85  ? 428 HIS A C    1 
ATOM 6338 O O    . HIS A 1 428 ? 128.198 111.964 90.754  1.00 74.16  ? 428 HIS A O    1 
ATOM 6339 C CB   . HIS A 1 428 ? 127.466 109.248 89.849  1.00 91.85  ? 428 HIS A CB   1 
ATOM 6340 C CG   . HIS A 1 428 ? 126.436 108.161 89.866  1.00 94.94  ? 428 HIS A CG   1 
ATOM 6341 N ND1  . HIS A 1 428 ? 125.208 108.293 89.255  1.00 85.20  ? 428 HIS A ND1  1 
ATOM 6342 C CD2  . HIS A 1 428 ? 126.451 106.924 90.416  1.00 101.08 ? 428 HIS A CD2  1 
ATOM 6343 C CE1  . HIS A 1 428 ? 124.509 107.186 89.430  1.00 90.74  ? 428 HIS A CE1  1 
ATOM 6344 N NE2  . HIS A 1 428 ? 125.241 106.339 90.131  1.00 98.74  ? 428 HIS A NE2  1 
ATOM 6345 H H    . HIS A 1 428 ? 127.205 109.883 87.451  1.00 80.70  ? 428 HIS A H    1 
ATOM 6346 H HA   . HIS A 1 428 ? 126.122 110.787 89.735  1.00 87.77  ? 428 HIS A HA   1 
ATOM 6347 H HB2  . HIS A 1 428 ? 128.212 108.942 89.309  1.00 88.70  ? 428 HIS A HB2  1 
ATOM 6348 H HB3  . HIS A 1 428 ? 127.759 109.393 90.762  1.00 89.95  ? 428 HIS A HB3  1 
ATOM 6349 H HD2  . HIS A 1 428 ? 127.149 106.541 90.897  1.00 97.50  ? 428 HIS A HD2  1 
ATOM 6350 H HE1  . HIS A 1 428 ? 123.649 107.030 89.113  1.00 89.97  ? 428 HIS A HE1  1 
ATOM 6351 H HE2  . HIS A 1 428 ? 124.999 105.549 90.370  1.00 96.75  ? 428 HIS A HE2  1 
ATOM 6352 N N    . GLU A 1 429 ? 128.519 112.320 88.552  1.00 79.33  ? 429 GLU A N    1 
ATOM 6353 C CA   . GLU A 1 429 ? 129.453 113.415 88.795  1.00 80.76  ? 429 GLU A CA   1 
ATOM 6354 C C    . GLU A 1 429 ? 128.767 114.584 89.490  1.00 76.60  ? 429 GLU A C    1 
ATOM 6355 O O    . GLU A 1 429 ? 129.326 115.176 90.422  1.00 80.31  ? 429 GLU A O    1 
ATOM 6356 C CB   . GLU A 1 429 ? 130.086 113.877 87.480  1.00 86.31  ? 429 GLU A CB   1 
ATOM 6357 C CG   . GLU A 1 429 ? 130.572 112.753 86.575  1.00 88.62  ? 429 GLU A CG   1 
ATOM 6358 C CD   . GLU A 1 429 ? 131.418 111.733 87.312  1.00 92.20  ? 429 GLU A CD   1 
ATOM 6359 O OE1  . GLU A 1 429 ? 130.860 110.969 88.127  1.00 85.40  ? 429 GLU A OE1  1 
ATOM 6360 O OE2  . GLU A 1 429 ? 132.645 111.700 87.080  1.00 98.80  ? 429 GLU A OE2  1 
ATOM 6361 H H    . GLU A 1 429 ? 128.382 112.140 87.723  1.00 81.87  ? 429 GLU A H    1 
ATOM 6362 H HA   . GLU A 1 429 ? 130.164 113.099 89.375  1.00 81.86  ? 429 GLU A HA   1 
ATOM 6363 H HB2  . GLU A 1 429 ? 129.428 114.387 86.982  1.00 85.63  ? 429 GLU A HB2  1 
ATOM 6364 H HB3  . GLU A 1 429 ? 130.848 114.441 87.684  1.00 84.28  ? 429 GLU A HB3  1 
ATOM 6365 H HG2  . GLU A 1 429 ? 129.808 112.293 86.194  1.00 86.04  ? 429 GLU A HG2  1 
ATOM 6366 H HG3  . GLU A 1 429 ? 131.114 113.134 85.866  1.00 87.03  ? 429 GLU A HG3  1 
ATOM 6367 N N    . MET A 1 430 ? 127.558 114.932 89.057  1.00 70.46  ? 430 MET A N    1 
ATOM 6368 C CA   . MET A 1 430 ? 126.822 116.068 89.612  1.00 69.51  ? 430 MET A CA   1 
ATOM 6369 C C    . MET A 1 430 ? 125.890 115.545 90.701  1.00 63.84  ? 430 MET A C    1 
ATOM 6370 O O    . MET A 1 430 ? 124.747 115.167 90.443  1.00 63.02  ? 430 MET A O    1 
ATOM 6371 C CB   . MET A 1 430 ? 126.054 116.822 88.528  1.00 63.41  ? 430 MET A CB   1 
ATOM 6372 C CG   . MET A 1 430 ? 126.682 116.816 87.132  1.00 65.01  ? 430 MET A CG   1 
ATOM 6373 S SD   . MET A 1 430 ? 125.471 117.158 85.838  1.00 85.51  ? 430 MET A SD   1 
ATOM 6374 C CE   . MET A 1 430 ? 126.254 116.407 84.412  1.00 74.88  ? 430 MET A CE   1 
ATOM 6375 H H    . MET A 1 430 ? 127.134 114.518 88.433  1.00 72.85  ? 430 MET A H    1 
ATOM 6376 H HA   . MET A 1 430 ? 127.452 116.689 90.011  1.00 72.61  ? 430 MET A HA   1 
ATOM 6377 H HB2  . MET A 1 430 ? 125.170 116.430 88.450  1.00 65.71  ? 430 MET A HB2  1 
ATOM 6378 H HB3  . MET A 1 430 ? 125.972 117.745 88.806  1.00 69.02  ? 430 MET A HB3  1 
ATOM 6379 H HG2  . MET A 1 430 ? 127.364 117.504 87.090  1.00 69.61  ? 430 MET A HG2  1 
ATOM 6380 H HG3  . MET A 1 430 ? 127.072 115.949 86.943  1.00 67.26  ? 430 MET A HG3  1 
ATOM 6381 H HE1  . MET A 1 430 ? 125.605 116.349 83.692  1.00 74.69  ? 430 MET A HE1  1 
ATOM 6382 H HE2  . MET A 1 430 ? 127.005 116.959 84.139  1.00 76.10  ? 430 MET A HE2  1 
ATOM 6383 H HE3  . MET A 1 430 ? 126.566 115.521 84.649  1.00 74.33  ? 430 MET A HE3  1 
ATOM 6384 N N    . GLY A 1 431 ? 126.397 115.518 91.935  1.00 58.14  ? 431 GLY A N    1 
ATOM 6385 C CA   . GLY A 1 431 ? 125.562 115.133 93.061  1.00 60.64  ? 431 GLY A CA   1 
ATOM 6386 C C    . GLY A 1 431 ? 124.486 116.155 93.373  1.00 53.94  ? 431 GLY A C    1 
ATOM 6387 O O    . GLY A 1 431 ? 123.368 115.796 93.754  1.00 54.02  ? 431 GLY A O    1 
ATOM 6388 H H    . GLY A 1 431 ? 127.209 115.714 92.140  1.00 63.15  ? 431 GLY A H    1 
ATOM 6389 H HA2  . GLY A 1 431 ? 125.134 114.284 92.870  1.00 62.43  ? 431 GLY A HA2  1 
ATOM 6390 H HA3  . GLY A 1 431 ? 126.117 115.024 93.849  1.00 63.45  ? 431 GLY A HA3  1 
ATOM 6391 N N    . ALA A 1 432 ? 124.809 117.443 93.232  1.00 47.12  ? 432 ALA A N    1 
ATOM 6392 C CA   . ALA A 1 432 ? 123.859 118.490 93.594  1.00 47.28  ? 432 ALA A CA   1 
ATOM 6393 C C    . ALA A 1 432 ? 122.592 118.401 92.752  1.00 52.56  ? 432 ALA A C    1 
ATOM 6394 O O    . ALA A 1 432 ? 121.474 118.468 93.279  1.00 55.20  ? 432 ALA A O    1 
ATOM 6395 C CB   . ALA A 1 432 ? 124.513 119.863 93.436  1.00 46.21  ? 432 ALA A CB   1 
ATOM 6396 H H    . ALA A 1 432 ? 125.562 117.730 92.934  1.00 50.14  ? 432 ALA A H    1 
ATOM 6397 H HA   . ALA A 1 432 ? 123.608 118.382 94.525  1.00 50.78  ? 432 ALA A HA   1 
ATOM 6398 H HB1  . ALA A 1 432 ? 123.868 120.548 93.672  1.00 47.16  ? 432 ALA A HB1  1 
ATOM 6399 H HB2  . ALA A 1 432 ? 125.282 119.917 94.024  1.00 50.14  ? 432 ALA A HB2  1 
ATOM 6400 H HB3  . ALA A 1 432 ? 124.792 119.977 92.513  1.00 46.79  ? 432 ALA A HB3  1 
ATOM 6401 N N    . LEU A 1 433 ? 122.745 118.252 91.434  1.00 51.45  ? 433 LEU A N    1 
ATOM 6402 C CA   . LEU A 1 433 ? 121.575 118.171 90.567  1.00 41.20  ? 433 LEU A CA   1 
ATOM 6403 C C    . LEU A 1 433 ? 120.766 116.912 90.849  1.00 40.28  ? 433 LEU A C    1 
ATOM 6404 O O    . LEU A 1 433 ? 119.531 116.947 90.838  1.00 42.24  ? 433 LEU A O    1 
ATOM 6405 C CB   . LEU A 1 433 ? 122.000 118.226 89.097  1.00 41.35  ? 433 LEU A CB   1 
ATOM 6406 C CG   . LEU A 1 433 ? 122.504 119.564 88.533  1.00 51.65  ? 433 LEU A CG   1 
ATOM 6407 C CD1  . LEU A 1 433 ? 121.746 120.755 89.112  1.00 56.82  ? 433 LEU A CD1  1 
ATOM 6408 C CD2  . LEU A 1 433 ? 124.002 119.736 88.746  1.00 54.88  ? 433 LEU A CD2  1 
ATOM 6409 H H    . LEU A 1 433 ? 123.501 118.191 91.029  1.00 51.47  ? 433 LEU A H    1 
ATOM 6410 H HA   . LEU A 1 433 ? 120.997 118.927 90.751  1.00 44.50  ? 433 LEU A HA   1 
ATOM 6411 H HB2  . LEU A 1 433 ? 122.714 117.582 88.971  1.00 47.00  ? 433 LEU A HB2  1 
ATOM 6412 H HB3  . LEU A 1 433 ? 121.238 117.963 88.557  1.00 44.68  ? 433 LEU A HB3  1 
ATOM 6413 H HG   . LEU A 1 433 ? 122.350 119.566 87.575  1.00 52.19  ? 433 LEU A HG   1 
ATOM 6414 H HD11 . LEU A 1 433 ? 121.999 121.555 88.626  1.00 56.54  ? 433 LEU A HD11 1 
ATOM 6415 H HD12 . LEU A 1 433 ? 120.794 120.598 89.019  1.00 53.18  ? 433 LEU A HD12 1 
ATOM 6416 H HD13 . LEU A 1 433 ? 121.977 120.851 90.049  1.00 53.39  ? 433 LEU A HD13 1 
ATOM 6417 H HD21 . LEU A 1 433 ? 124.241 120.659 88.569  1.00 53.56  ? 433 LEU A HD21 1 
ATOM 6418 H HD22 . LEU A 1 433 ? 124.224 119.508 89.661  1.00 54.33  ? 433 LEU A HD22 1 
ATOM 6419 H HD23 . LEU A 1 433 ? 124.473 119.151 88.133  1.00 56.72  ? 433 LEU A HD23 1 
ATOM 6420 N N    . ARG A 1 434 ? 121.441 115.789 91.101  1.00 39.77  ? 434 ARG A N    1 
ATOM 6421 C CA   . ARG A 1 434 ? 120.730 114.556 91.423  1.00 47.23  ? 434 ARG A CA   1 
ATOM 6422 C C    . ARG A 1 434 ? 119.906 114.722 92.695  1.00 46.97  ? 434 ARG A C    1 
ATOM 6423 O O    . ARG A 1 434 ? 118.733 114.329 92.751  1.00 58.22  ? 434 ARG A O    1 
ATOM 6424 C CB   . ARG A 1 434 ? 121.732 113.410 91.570  1.00 50.21  ? 434 ARG A CB   1 
ATOM 6425 C CG   . ARG A 1 434 ? 121.162 112.029 91.294  1.00 58.03  ? 434 ARG A CG   1 
ATOM 6426 C CD   . ARG A 1 434 ? 122.208 111.117 90.672  1.00 64.37  ? 434 ARG A CD   1 
ATOM 6427 N NE   . ARG A 1 434 ? 121.922 109.708 90.910  1.00 76.37  ? 434 ARG A NE   1 
ATOM 6428 C CZ   . ARG A 1 434 ? 122.044 109.106 92.086  1.00 79.66  ? 434 ARG A CZ   1 
ATOM 6429 N NH1  . ARG A 1 434 ? 122.457 109.762 93.159  1.00 75.03  ? 434 ARG A NH1  1 
ATOM 6430 N NH2  . ARG A 1 434 ? 121.748 107.814 92.187  1.00 77.34  ? 434 ARG A NH2  1 
ATOM 6431 H H    . ARG A 1 434 ? 122.299 115.717 91.091  1.00 46.84  ? 434 ARG A H    1 
ATOM 6432 H HA   . ARG A 1 434 ? 120.125 114.340 90.696  1.00 50.46  ? 434 ARG A HA   1 
ATOM 6433 H HB2  . ARG A 1 434 ? 122.463 113.556 90.949  1.00 52.09  ? 434 ARG A HB2  1 
ATOM 6434 H HB3  . ARG A 1 434 ? 122.072 113.411 92.479  1.00 53.22  ? 434 ARG A HB3  1 
ATOM 6435 H HG2  . ARG A 1 434 ? 120.866 111.632 92.127  1.00 59.47  ? 434 ARG A HG2  1 
ATOM 6436 H HG3  . ARG A 1 434 ? 120.420 112.105 90.674  1.00 55.74  ? 434 ARG A HG3  1 
ATOM 6437 H HD2  . ARG A 1 434 ? 122.228 111.263 89.713  1.00 64.52  ? 434 ARG A HD2  1 
ATOM 6438 H HD3  . ARG A 1 434 ? 123.075 111.318 91.058  1.00 65.44  ? 434 ARG A HD3  1 
ATOM 6439 H HE   . ARG A 1 434 ? 121.615 109.245 90.254  1.00 70.44  ? 434 ARG A HE   1 
ATOM 6440 H HH11 . ARG A 1 434 ? 122.652 110.597 93.106  1.00 70.07  ? 434 ARG A HH11 1 
ATOM 6441 H HH12 . ARG A 1 434 ? 122.530 109.351 93.910  1.00 70.29  ? 434 ARG A HH12 1 
ATOM 6442 H HH21 . ARG A 1 434 ? 121.480 107.378 91.496  1.00 75.47  ? 434 ARG A HH21 1 
ATOM 6443 H HH22 . ARG A 1 434 ? 121.825 107.413 92.945  1.00 74.66  ? 434 ARG A HH22 1 
ATOM 6444 N N    . SER A 1 435 ? 120.508 115.317 93.727  1.00 39.82  ? 435 SER A N    1 
ATOM 6445 C CA   . SER A 1 435 ? 119.791 115.536 94.978  1.00 43.04  ? 435 SER A CA   1 
ATOM 6446 C C    . SER A 1 435 ? 118.611 116.477 94.777  1.00 41.64  ? 435 SER A C    1 
ATOM 6447 O O    . SER A 1 435 ? 117.525 116.248 95.324  1.00 42.32  ? 435 SER A O    1 
ATOM 6448 C CB   . SER A 1 435 ? 120.746 116.092 96.035  1.00 30.00  ? 435 SER A CB   1 
ATOM 6449 O OG   . SER A 1 435 ? 120.235 115.894 97.341  1.00 30.00  ? 435 SER A OG   1 
ATOM 6450 H H    . SER A 1 435 ? 121.320 115.599 93.727  1.00 45.58  ? 435 SER A H    1 
ATOM 6451 H HA   . SER A 1 435 ? 119.449 114.687 95.299  1.00 46.12  ? 435 SER A HA   1 
ATOM 6452 N N    . ALA A 1 436 ? 118.804 117.546 94.001  1.00 39.42  ? 436 ALA A N    1 
ATOM 6453 C CA   . ALA A 1 436 ? 117.710 118.479 93.752  1.00 41.50  ? 436 ALA A CA   1 
ATOM 6454 C C    . ALA A 1 436 ? 116.564 117.798 93.016  1.00 39.95  ? 436 ALA A C    1 
ATOM 6455 O O    . ALA A 1 436 ? 115.392 118.000 93.353  1.00 41.67  ? 436 ALA A O    1 
ATOM 6456 C CB   . ALA A 1 436 ? 118.219 119.680 92.957  1.00 38.50  ? 436 ALA A CB   1 
ATOM 6457 H H    . ALA A 1 436 ? 119.545 117.749 93.615  1.00 43.23  ? 436 ALA A H    1 
ATOM 6458 H HA   . ALA A 1 436 ? 117.371 118.803 94.601  1.00 42.02  ? 436 ALA A HA   1 
ATOM 6459 H HB1  . ALA A 1 436 ? 118.577 119.369 92.110  1.00 41.13  ? 436 ALA A HB1  1 
ATOM 6460 H HB2  . ALA A 1 436 ? 117.481 120.290 92.799  1.00 39.32  ? 436 ALA A HB2  1 
ATOM 6461 H HB3  . ALA A 1 436 ? 118.914 120.125 93.467  1.00 40.55  ? 436 ALA A HB3  1 
ATOM 6462 N N    . LEU A 1 437 ? 116.882 116.986 92.005  1.00 38.17  ? 437 LEU A N    1 
ATOM 6463 C CA   . LEU A 1 437 ? 115.838 116.281 91.269  1.00 35.50  ? 437 LEU A CA   1 
ATOM 6464 C C    . LEU A 1 437 ? 115.083 115.321 92.180  1.00 39.99  ? 437 LEU A C    1 
ATOM 6465 O O    . LEU A 1 437 ? 113.849 115.242 92.127  1.00 45.37  ? 437 LEU A O    1 
ATOM 6466 C CB   . LEU A 1 437 ? 116.451 115.530 90.084  1.00 34.38  ? 437 LEU A CB   1 
ATOM 6467 C CG   . LEU A 1 437 ? 116.131 116.044 88.677  1.00 38.41  ? 437 LEU A CG   1 
ATOM 6468 C CD1  . LEU A 1 437 ? 116.844 115.196 87.636  1.00 44.77  ? 437 LEU A CD1  1 
ATOM 6469 C CD2  . LEU A 1 437 ? 114.634 116.049 88.410  1.00 37.58  ? 437 LEU A CD2  1 
ATOM 6470 H H    . LEU A 1 437 ? 117.682 116.832 91.732  1.00 40.37  ? 437 LEU A H    1 
ATOM 6471 H HA   . LEU A 1 437 ? 115.205 116.930 90.927  1.00 38.20  ? 437 LEU A HA   1 
ATOM 6472 H HB2  . LEU A 1 437 ? 117.416 115.548 90.179  1.00 39.23  ? 437 LEU A HB2  1 
ATOM 6473 H HB3  . LEU A 1 437 ? 116.147 114.610 90.124  1.00 38.95  ? 437 LEU A HB3  1 
ATOM 6474 H HG   . LEU A 1 437 ? 116.453 116.955 88.591  1.00 40.47  ? 437 LEU A HG   1 
ATOM 6475 H HD11 . LEU A 1 437 ? 116.629 115.534 86.752  1.00 42.60  ? 437 LEU A HD11 1 
ATOM 6476 H HD12 . LEU A 1 437 ? 117.801 115.249 87.787  1.00 42.64  ? 437 LEU A HD12 1 
ATOM 6477 H HD13 . LEU A 1 437 ? 116.546 114.277 87.720  1.00 43.14  ? 437 LEU A HD13 1 
ATOM 6478 H HD21 . LEU A 1 437 ? 114.480 116.327 87.493  1.00 38.78  ? 437 LEU A HD21 1 
ATOM 6479 H HD22 . LEU A 1 437 ? 114.289 115.153 88.545  1.00 40.43  ? 437 LEU A HD22 1 
ATOM 6480 H HD23 . LEU A 1 437 ? 114.201 116.668 89.017  1.00 41.61  ? 437 LEU A HD23 1 
ATOM 6481 N N    . ALA A 1 438 ? 115.807 114.590 93.030  1.00 38.54  ? 438 ALA A N    1 
ATOM 6482 C CA   . ALA A 1 438 ? 115.149 113.680 93.963  1.00 36.76  ? 438 ALA A CA   1 
ATOM 6483 C C    . ALA A 1 438 ? 114.236 114.434 94.922  1.00 42.87  ? 438 ALA A C    1 
ATOM 6484 O O    . ALA A 1 438 ? 113.113 113.993 95.207  1.00 48.33  ? 438 ALA A O    1 
ATOM 6485 C CB   . ALA A 1 438 ? 116.201 112.888 94.737  1.00 39.60  ? 438 ALA A CB   1 
ATOM 6486 H H    . ALA A 1 438 ? 116.665 114.603 93.085  1.00 41.38  ? 438 ALA A H    1 
ATOM 6487 H HA   . ALA A 1 438 ? 114.607 113.050 93.462  1.00 40.52  ? 438 ALA A HA   1 
ATOM 6488 H HB1  . ALA A 1 438 ? 115.806 112.581 95.566  1.00 44.56  ? 438 ALA A HB1  1 
ATOM 6489 H HB2  . ALA A 1 438 ? 116.493 112.133 94.204  1.00 44.42  ? 438 ALA A HB2  1 
ATOM 6490 H HB3  . ALA A 1 438 ? 116.950 113.471 94.936  1.00 43.31  ? 438 ALA A HB3  1 
ATOM 6491 N N    . VAL A 1 439 ? 114.704 115.573 95.434  1.00 40.17  ? 439 VAL A N    1 
ATOM 6492 C CA   . VAL A 1 439 ? 113.907 116.352 96.376  1.00 43.15  ? 439 VAL A CA   1 
ATOM 6493 C C    . VAL A 1 439 ? 112.642 116.867 95.700  1.00 45.42  ? 439 VAL A C    1 
ATOM 6494 O O    . VAL A 1 439 ? 111.546 116.821 96.277  1.00 45.00  ? 439 VAL A O    1 
ATOM 6495 C CB   . VAL A 1 439 ? 114.757 117.498 96.956  1.00 43.18  ? 439 VAL A CB   1 
ATOM 6496 C CG1  . VAL A 1 439 ? 113.886 118.509 97.665  1.00 41.31  ? 439 VAL A CG1  1 
ATOM 6497 C CG2  . VAL A 1 439 ? 115.807 116.946 97.906  1.00 41.40  ? 439 VAL A CG2  1 
ATOM 6498 H H    . VAL A 1 439 ? 115.473 115.912 95.252  1.00 40.97  ? 439 VAL A H    1 
ATOM 6499 H HA   . VAL A 1 439 ? 113.640 115.778 97.110  1.00 41.86  ? 439 VAL A HA   1 
ATOM 6500 H HB   . VAL A 1 439 ? 115.216 117.952 96.231  1.00 42.60  ? 439 VAL A HB   1 
ATOM 6501 H HG11 . VAL A 1 439 ? 113.360 119.001 97.016  1.00 42.45  ? 439 VAL A HG11 1 
ATOM 6502 H HG12 . VAL A 1 439 ? 113.308 118.031 98.278  1.00 41.48  ? 439 VAL A HG12 1 
ATOM 6503 H HG13 . VAL A 1 439 ? 114.455 119.122 98.157  1.00 40.29  ? 439 VAL A HG13 1 
ATOM 6504 H HG21 . VAL A 1 439 ? 116.353 117.678 98.233  1.00 40.60  ? 439 VAL A HG21 1 
ATOM 6505 H HG22 . VAL A 1 439 ? 115.361 116.509 98.649  1.00 42.24  ? 439 VAL A HG22 1 
ATOM 6506 H HG23 . VAL A 1 439 ? 116.360 116.307 97.431  1.00 42.66  ? 439 VAL A HG23 1 
ATOM 6507 N N    . LEU A 1 440 ? 112.771 117.366 94.467  1.00 44.26  ? 440 LEU A N    1 
ATOM 6508 C CA   . LEU A 1 440 ? 111.597 117.836 93.739  1.00 37.67  ? 440 LEU A CA   1 
ATOM 6509 C C    . LEU A 1 440 ? 110.615 116.699 93.488  1.00 42.29  ? 440 LEU A C    1 
ATOM 6510 O O    . LEU A 1 440 ? 109.398 116.887 93.597  1.00 51.26  ? 440 LEU A O    1 
ATOM 6511 C CB   . LEU A 1 440 ? 112.015 118.482 92.416  1.00 37.94  ? 440 LEU A CB   1 
ATOM 6512 C CG   . LEU A 1 440 ? 112.893 119.738 92.470  1.00 38.58  ? 440 LEU A CG   1 
ATOM 6513 C CD1  . LEU A 1 440 ? 112.684 120.577 91.218  1.00 43.64  ? 440 LEU A CD1  1 
ATOM 6514 C CD2  . LEU A 1 440 ? 112.623 120.567 93.717  1.00 37.02  ? 440 LEU A CD2  1 
ATOM 6515 H H    . LEU A 1 440 ? 113.513 117.440 94.040  1.00 43.24  ? 440 LEU A H    1 
ATOM 6516 H HA   . LEU A 1 440 ? 111.138 118.501 94.274  1.00 38.96  ? 440 LEU A HA   1 
ATOM 6517 H HB2  . LEU A 1 440 ? 112.503 117.820 91.902  1.00 40.08  ? 440 LEU A HB2  1 
ATOM 6518 H HB3  . LEU A 1 440 ? 111.208 118.723 91.934  1.00 39.81  ? 440 LEU A HB3  1 
ATOM 6519 H HG   . LEU A 1 440 ? 113.824 119.471 92.488  1.00 39.60  ? 440 LEU A HG   1 
ATOM 6520 H HD11 . LEU A 1 440 ? 112.895 120.039 90.439  1.00 42.94  ? 440 LEU A HD11 1 
ATOM 6521 H HD12 . LEU A 1 440 ? 111.759 120.864 91.182  1.00 44.52  ? 440 LEU A HD12 1 
ATOM 6522 H HD13 . LEU A 1 440 ? 113.270 121.350 91.255  1.00 41.19  ? 440 LEU A HD13 1 
ATOM 6523 H HD21 . LEU A 1 440 ? 113.084 121.417 93.636  1.00 38.96  ? 440 LEU A HD21 1 
ATOM 6524 H HD22 . LEU A 1 440 ? 111.668 120.716 93.795  1.00 38.25  ? 440 LEU A HD22 1 
ATOM 6525 H HD23 . LEU A 1 440 ? 112.948 120.087 94.494  1.00 38.82  ? 440 LEU A HD23 1 
ATOM 6526 N N    . GLY A 1 441 ? 111.120 115.513 93.144  1.00 40.67  ? 441 GLY A N    1 
ATOM 6527 C CA   . GLY A 1 441 ? 110.231 114.380 92.947  1.00 39.33  ? 441 GLY A CA   1 
ATOM 6528 C C    . GLY A 1 441 ? 109.465 114.014 94.204  1.00 43.75  ? 441 GLY A C    1 
ATOM 6529 O O    . GLY A 1 441 ? 108.258 113.754 94.158  1.00 47.74  ? 441 GLY A O    1 
ATOM 6530 H H    . GLY A 1 441 ? 111.955 115.345 93.023  1.00 42.31  ? 441 GLY A H    1 
ATOM 6531 H HA2  . GLY A 1 441 ? 109.592 114.587 92.247  1.00 40.29  ? 441 GLY A HA2  1 
ATOM 6532 H HA3  . GLY A 1 441 ? 110.750 113.608 92.669  1.00 41.26  ? 441 GLY A HA3  1 
ATOM 6533 N N    . LEU A 1 442 ? 110.156 113.979 95.346  1.00 45.05  ? 442 LEU A N    1 
ATOM 6534 C CA   . LEU A 1 442 ? 109.476 113.654 96.596  1.00 47.74  ? 442 LEU A CA   1 
ATOM 6535 C C    . LEU A 1 442 ? 108.432 114.710 96.945  1.00 47.72  ? 442 LEU A C    1 
ATOM 6536 O O    . LEU A 1 442 ? 107.322 114.380 97.389  1.00 48.72  ? 442 LEU A O    1 
ATOM 6537 C CB   . LEU A 1 442 ? 110.494 113.504 97.726  1.00 51.56  ? 442 LEU A CB   1 
ATOM 6538 C CG   . LEU A 1 442 ? 110.961 112.074 98.018  1.00 55.73  ? 442 LEU A CG   1 
ATOM 6539 C CD1  . LEU A 1 442 ? 109.823 111.235 98.585  1.00 58.01  ? 442 LEU A CD1  1 
ATOM 6540 C CD2  . LEU A 1 442 ? 111.540 111.419 96.773  1.00 60.20  ? 442 LEU A CD2  1 
ATOM 6541 H H    . LEU A 1 442 ? 110.998 114.136 95.420  1.00 45.81  ? 442 LEU A H    1 
ATOM 6542 H HA   . LEU A 1 442 ? 109.017 112.807 96.489  1.00 48.63  ? 442 LEU A HA   1 
ATOM 6543 H HB2  . LEU A 1 442 ? 111.281 114.025 97.501  1.00 48.70  ? 442 LEU A HB2  1 
ATOM 6544 H HB3  . LEU A 1 442 ? 110.099 113.852 98.541  1.00 51.27  ? 442 LEU A HB3  1 
ATOM 6545 H HG   . LEU A 1 442 ? 111.663 112.106 98.687  1.00 53.70  ? 442 LEU A HG   1 
ATOM 6546 H HD11 . LEU A 1 442 ? 110.184 110.398 98.917  1.00 60.09  ? 442 LEU A HD11 1 
ATOM 6547 H HD12 . LEU A 1 442 ? 109.401 111.724 99.308  1.00 57.56  ? 442 LEU A HD12 1 
ATOM 6548 H HD13 . LEU A 1 442 ? 109.178 111.061 97.882  1.00 56.96  ? 442 LEU A HD13 1 
ATOM 6549 H HD21 . LEU A 1 442 ? 110.834 111.307 96.117  1.00 54.44  ? 442 LEU A HD21 1 
ATOM 6550 H HD22 . LEU A 1 442 ? 112.240 111.986 96.413  1.00 54.07  ? 442 LEU A HD22 1 
ATOM 6551 H HD23 . LEU A 1 442 ? 111.906 110.553 97.013  1.00 59.52  ? 442 LEU A HD23 1 
ATOM 6552 N N    . GLY A 1 443 ? 108.766 115.987 96.749  1.00 46.29  ? 443 GLY A N    1 
ATOM 6553 C CA   . GLY A 1 443 ? 107.783 117.034 96.977  1.00 49.22  ? 443 GLY A CA   1 
ATOM 6554 C C    . GLY A 1 443 ? 106.570 116.888 96.078  1.00 48.03  ? 443 GLY A C    1 
ATOM 6555 O O    . GLY A 1 443 ? 105.432 117.096 96.510  1.00 52.13  ? 443 GLY A O    1 
ATOM 6556 H H    . GLY A 1 443 ? 109.538 116.264 96.491  1.00 46.19  ? 443 GLY A H    1 
ATOM 6557 H HA2  . GLY A 1 443 ? 107.489 117.007 97.900  1.00 50.71  ? 443 GLY A HA2  1 
ATOM 6558 H HA3  . GLY A 1 443 ? 108.188 117.899 96.807  1.00 47.33  ? 443 GLY A HA3  1 
ATOM 6559 N N    . GLY A 1 444 ? 106.797 116.533 94.813  1.00 42.20  ? 444 GLY A N    1 
ATOM 6560 C CA   . GLY A 1 444 ? 105.683 116.311 93.908  1.00 39.25  ? 444 GLY A CA   1 
ATOM 6561 C C    . GLY A 1 444 ? 104.798 115.163 94.350  1.00 45.01  ? 444 GLY A C    1 
ATOM 6562 O O    . GLY A 1 444 ? 103.571 115.243 94.261  1.00 47.86  ? 444 GLY A O    1 
ATOM 6563 H H    . GLY A 1 444 ? 107.574 116.415 94.465  1.00 44.80  ? 444 GLY A H    1 
ATOM 6564 H HA2  . GLY A 1 444 ? 105.143 117.115 93.856  1.00 42.21  ? 444 GLY A HA2  1 
ATOM 6565 H HA3  . GLY A 1 444 ? 106.023 116.113 93.022  1.00 41.51  ? 444 GLY A HA3  1 
ATOM 6566 N N    . LEU A 1 445 ? 105.407 114.074 94.825  1.00 50.54  ? 445 LEU A N    1 
ATOM 6567 C CA   . LEU A 1 445 ? 104.608 112.965 95.341  1.00 47.81  ? 445 LEU A CA   1 
ATOM 6568 C C    . LEU A 1 445 ? 103.776 113.397 96.544  1.00 48.77  ? 445 LEU A C    1 
ATOM 6569 O O    . LEU A 1 445 ? 102.605 113.017 96.669  1.00 47.52  ? 445 LEU A O    1 
ATOM 6570 C CB   . LEU A 1 445 ? 105.501 111.781 95.714  1.00 45.52  ? 445 LEU A CB   1 
ATOM 6571 C CG   . LEU A 1 445 ? 105.487 110.568 94.779  1.00 52.74  ? 445 LEU A CG   1 
ATOM 6572 C CD1  . LEU A 1 445 ? 104.129 109.889 94.853  1.00 57.59  ? 445 LEU A CD1  1 
ATOM 6573 C CD2  . LEU A 1 445 ? 105.835 110.928 93.345  1.00 50.83  ? 445 LEU A CD2  1 
ATOM 6574 H H    . LEU A 1 445 ? 106.258 113.958 94.858  1.00 47.99  ? 445 LEU A H    1 
ATOM 6575 H HA   . LEU A 1 445 ? 103.995 112.675 94.647  1.00 47.18  ? 445 LEU A HA   1 
ATOM 6576 H HB2  . LEU A 1 445 ? 106.416 112.095 95.760  1.00 48.95  ? 445 LEU A HB2  1 
ATOM 6577 H HB3  . LEU A 1 445 ? 105.227 111.464 96.589  1.00 48.81  ? 445 LEU A HB3  1 
ATOM 6578 H HG   . LEU A 1 445 ? 106.150 109.930 95.089  1.00 49.06  ? 445 LEU A HG   1 
ATOM 6579 H HD11 . LEU A 1 445 ? 104.064 109.232 94.144  1.00 54.38  ? 445 LEU A HD11 1 
ATOM 6580 H HD12 . LEU A 1 445 ? 104.042 109.458 95.717  1.00 54.79  ? 445 LEU A HD12 1 
ATOM 6581 H HD13 . LEU A 1 445 ? 103.431 110.555 94.744  1.00 54.53  ? 445 LEU A HD13 1 
ATOM 6582 H HD21 . LEU A 1 445 ? 105.863 110.117 92.812  1.00 51.07  ? 445 LEU A HD21 1 
ATOM 6583 H HD22 . LEU A 1 445 ? 105.155 111.525 92.998  1.00 48.25  ? 445 LEU A HD22 1 
ATOM 6584 H HD23 . LEU A 1 445 ? 106.704 111.359 93.332  1.00 50.63  ? 445 LEU A HD23 1 
ATOM 6585 N N    . GLY A 1 446 ? 104.365 114.182 97.446  1.00 50.44  ? 446 GLY A N    1 
ATOM 6586 C CA   . GLY A 1 446 ? 103.599 114.674 98.583  1.00 52.91  ? 446 GLY A CA   1 
ATOM 6587 C C    . GLY A 1 446 ? 102.423 115.531 98.156  1.00 51.22  ? 446 GLY A C    1 
ATOM 6588 O O    . GLY A 1 446 ? 101.304 115.383 98.663  1.00 51.84  ? 446 GLY A O    1 
ATOM 6589 H H    . GLY A 1 446 ? 105.187 114.438 97.424  1.00 49.85  ? 446 GLY A H    1 
ATOM 6590 H HA2  . GLY A 1 446 ? 103.263 113.921 99.095  1.00 53.09  ? 446 GLY A HA2  1 
ATOM 6591 H HA3  . GLY A 1 446 ? 104.175 115.202 99.157  1.00 52.90  ? 446 GLY A HA3  1 
ATOM 6592 N N    . ALA A 1 447 ? 102.662 116.435 97.203  1.00 51.24  ? 447 ALA A N    1 
ATOM 6593 C CA   . ALA A 1 447 ? 101.588 117.281 96.692  1.00 50.20  ? 447 ALA A CA   1 
ATOM 6594 C C    . ALA A 1 447 ? 100.488 116.443 96.053  1.00 52.66  ? 447 ALA A C    1 
ATOM 6595 O O    . ALA A 1 447 ? 99.295  116.703 96.257  1.00 55.51  ? 447 ALA A O    1 
ATOM 6596 C CB   . ALA A 1 447 ? 102.153 118.280 95.684  1.00 48.29  ? 447 ALA A CB   1 
ATOM 6597 H H    . ALA A 1 447 ? 103.427 116.574 96.841  1.00 50.40  ? 447 ALA A H    1 
ATOM 6598 H HA   . ALA A 1 447 ? 101.206 117.787 97.424  1.00 50.15  ? 447 ALA A HA   1 
ATOM 6599 H HB1  . ALA A 1 447 ? 102.760 118.880 96.145  1.00 48.95  ? 447 ALA A HB1  1 
ATOM 6600 H HB2  . ALA A 1 447 ? 102.630 117.794 94.994  1.00 49.06  ? 447 ALA A HB2  1 
ATOM 6601 H HB3  . ALA A 1 447 ? 101.424 118.784 95.292  1.00 47.89  ? 447 ALA A HB3  1 
ATOM 6602 N N    . ALA A 1 448 ? 100.874 115.430 95.275  1.00 53.69  ? 448 ALA A N    1 
ATOM 6603 C CA   . ALA A 1 448 ? 99.887  114.563 94.645  1.00 49.49  ? 448 ALA A CA   1 
ATOM 6604 C C    . ALA A 1 448 ? 99.058  113.832 95.690  1.00 49.30  ? 448 ALA A C    1 
ATOM 6605 O O    . ALA A 1 448 ? 97.840  113.679 95.531  1.00 48.14  ? 448 ALA A O    1 
ATOM 6606 C CB   . ALA A 1 448 ? 100.582 113.568 93.719  1.00 47.53  ? 448 ALA A CB   1 
ATOM 6607 H H    . ALA A 1 448 ? 101.690 115.226 95.102  1.00 50.86  ? 448 ALA A H    1 
ATOM 6608 H HA   . ALA A 1 448 ? 99.284  115.103 94.111  1.00 48.42  ? 448 ALA A HA   1 
ATOM 6609 H HB1  . ALA A 1 448 ? 101.114 114.057 93.072  1.00 46.33  ? 448 ALA A HB1  1 
ATOM 6610 H HB2  . ALA A 1 448 ? 101.154 112.992 94.249  1.00 48.10  ? 448 ALA A HB2  1 
ATOM 6611 H HB3  . ALA A 1 448 ? 99.908  113.037 93.265  1.00 46.68  ? 448 ALA A HB3  1 
ATOM 6612 N N    . PHE A 1 449 ? 99.696  113.369 96.766  1.00 53.61  ? 449 PHE A N    1 
ATOM 6613 C CA   . PHE A 1 449 ? 98.940  112.688 97.810  1.00 54.55  ? 449 PHE A CA   1 
ATOM 6614 C C    . PHE A 1 449 ? 97.931  113.625 98.457  1.00 54.80  ? 449 PHE A C    1 
ATOM 6615 O O    . PHE A 1 449 ? 96.763  113.257 98.645  1.00 57.43  ? 449 PHE A O    1 
ATOM 6616 C CB   . PHE A 1 449 ? 99.882  112.131 98.875  1.00 55.36  ? 449 PHE A CB   1 
ATOM 6617 C CG   . PHE A 1 449 ? 99.206  111.848 100.187 1.00 58.89  ? 449 PHE A CG   1 
ATOM 6618 C CD1  . PHE A 1 449 ? 98.458  110.697 100.363 1.00 59.87  ? 449 PHE A CD1  1 
ATOM 6619 C CD2  . PHE A 1 449 ? 99.309  112.738 101.241 1.00 63.12  ? 449 PHE A CD2  1 
ATOM 6620 C CE1  . PHE A 1 449 ? 97.837  110.435 101.568 1.00 69.57  ? 449 PHE A CE1  1 
ATOM 6621 C CE2  . PHE A 1 449 ? 98.689  112.482 102.445 1.00 65.31  ? 449 PHE A CE2  1 
ATOM 6622 C CZ   . PHE A 1 449 ? 97.952  111.329 102.609 1.00 76.10  ? 449 PHE A CZ   1 
ATOM 6623 H H    . PHE A 1 449 ? 100.541 113.435 96.915  1.00 52.72  ? 449 PHE A H    1 
ATOM 6624 H HA   . PHE A 1 449 ? 98.458  111.944 97.415  1.00 54.06  ? 449 PHE A HA   1 
ATOM 6625 H HB2  . PHE A 1 449 ? 100.258 111.299 98.551  1.00 56.48  ? 449 PHE A HB2  1 
ATOM 6626 H HB3  . PHE A 1 449 ? 100.592 112.771 99.037  1.00 55.12  ? 449 PHE A HB3  1 
ATOM 6627 H HD1  . PHE A 1 449 ? 98.380  110.090 99.664  1.00 59.06  ? 449 PHE A HD1  1 
ATOM 6628 H HD2  . PHE A 1 449 ? 99.805  113.518 101.137 1.00 61.24  ? 449 PHE A HD2  1 
ATOM 6629 H HE1  . PHE A 1 449 ? 97.340  109.656 101.675 1.00 65.48  ? 449 PHE A HE1  1 
ATOM 6630 H HE2  . PHE A 1 449 ? 98.769  113.088 103.144 1.00 63.61  ? 449 PHE A HE2  1 
ATOM 6631 H HZ   . PHE A 1 449 ? 97.533  111.155 103.421 1.00 73.92  ? 449 PHE A HZ   1 
ATOM 6632 N N    . THR A 1 450 ? 98.358  114.844 98.801  1.00 53.73  ? 450 THR A N    1 
ATOM 6633 C CA   . THR A 1 450 ? 97.430  115.743 99.484  1.00 57.12  ? 450 THR A CA   1 
ATOM 6634 C C    . THR A 1 450 ? 96.301  116.169 98.557  1.00 52.86  ? 450 THR A C    1 
ATOM 6635 O O    . THR A 1 450 ? 95.189  116.441 99.020  1.00 48.97  ? 450 THR A O    1 
ATOM 6636 C CB   . THR A 1 450 ? 98.139  116.985 100.033 1.00 61.42  ? 450 THR A CB   1 
ATOM 6637 O OG1  . THR A 1 450 ? 97.158  117.966 100.394 1.00 56.95  ? 450 THR A OG1  1 
ATOM 6638 C CG2  . THR A 1 450 ? 99.045  117.602 98.996  1.00 58.58  ? 450 THR A CG2  1 
ATOM 6639 H H    . THR A 1 450 ? 99.146  115.149 98.663  1.00 54.64  ? 450 THR A H    1 
ATOM 6640 H HA   . THR A 1 450 ? 97.037  115.273 100.234 1.00 57.06  ? 450 THR A HA   1 
ATOM 6641 H HB   . THR A 1 450 ? 98.667  116.750 100.811 1.00 59.13  ? 450 THR A HB   1 
ATOM 6642 H HG1  . THR A 1 450 ? 97.535  118.651 100.702 1.00 55.78  ? 450 THR A HG1  1 
ATOM 6643 H HG21 . THR A 1 450 ? 99.445  118.413 99.348  1.00 55.91  ? 450 THR A HG21 1 
ATOM 6644 H HG22 . THR A 1 450 ? 99.749  116.988 98.761  1.00 55.72  ? 450 THR A HG22 1 
ATOM 6645 H HG23 . THR A 1 450 ? 98.533  117.820 98.202  1.00 55.57  ? 450 THR A HG23 1 
ATOM 6646 N N    . CYS A 1 451 ? 96.562  116.233 97.250  1.00 53.99  ? 451 CYS A N    1 
ATOM 6647 C CA   . CYS A 1 451 ? 95.500  116.576 96.311  1.00 54.10  ? 451 CYS A CA   1 
ATOM 6648 C C    . CYS A 1 451 ? 94.510  115.427 96.156  1.00 53.95  ? 451 CYS A C    1 
ATOM 6649 O O    . CYS A 1 451 ? 93.290  115.637 96.183  1.00 54.88  ? 451 CYS A O    1 
ATOM 6650 C CB   . CYS A 1 451 ? 96.099  116.958 94.960  1.00 57.16  ? 451 CYS A CB   1 
ATOM 6651 S SG   . CYS A 1 451 ? 94.888  117.062 93.627  1.00 64.57  ? 451 CYS A SG   1 
ATOM 6652 H H    . CYS A 1 451 ? 97.329  116.082 96.890  1.00 54.40  ? 451 CYS A H    1 
ATOM 6653 H HA   . CYS A 1 451 ? 95.017  117.345 96.652  1.00 55.06  ? 451 CYS A HA   1 
ATOM 6654 H HB2  . CYS A 1 451 ? 96.526  117.825 95.044  1.00 56.40  ? 451 CYS A HB2  1 
ATOM 6655 H HB3  . CYS A 1 451 ? 96.758  116.291 94.712  1.00 53.88  ? 451 CYS A HB3  1 
ATOM 6656 H HG   . CYS A 1 451 ? 95.447  117.384 92.616  1.00 53.74  ? 451 CYS A HG   1 
ATOM 6657 N N    . ILE A 1 452 ? 95.012  114.199 95.999  1.00 56.29  ? 452 ILE A N    1 
ATOM 6658 C CA   . ILE A 1 452 ? 94.110  113.070 95.790  1.00 55.82  ? 452 ILE A CA   1 
ATOM 6659 C C    . ILE A 1 452 ? 93.282  112.808 97.038  1.00 50.62  ? 452 ILE A C    1 
ATOM 6660 O O    . ILE A 1 452 ? 92.130  112.364 96.939  1.00 51.13  ? 452 ILE A O    1 
ATOM 6661 C CB   . ILE A 1 452 ? 94.889  111.812 95.355  1.00 55.83  ? 452 ILE A CB   1 
ATOM 6662 C CG1  . ILE A 1 452 ? 93.924  110.723 94.875  1.00 53.31  ? 452 ILE A CG1  1 
ATOM 6663 C CG2  . ILE A 1 452 ? 95.749  111.282 96.489  1.00 54.54  ? 452 ILE A CG2  1 
ATOM 6664 C CD1  . ILE A 1 452 ? 93.294  111.009 93.528  1.00 48.12  ? 452 ILE A CD1  1 
ATOM 6665 H H    . ILE A 1 452 ? 95.849  113.999 96.010  1.00 54.73  ? 452 ILE A H    1 
ATOM 6666 H HA   . ILE A 1 452 ? 93.496  113.295 95.074  1.00 55.69  ? 452 ILE A HA   1 
ATOM 6667 H HB   . ILE A 1 452 ? 95.470  112.051 94.616  1.00 54.33  ? 452 ILE A HB   1 
ATOM 6668 H HG12 . ILE A 1 452 ? 94.412  109.888 94.798  1.00 52.55  ? 452 ILE A HG12 1 
ATOM 6669 H HG13 . ILE A 1 452 ? 93.207  110.623 95.521  1.00 53.67  ? 452 ILE A HG13 1 
ATOM 6670 H HG21 . ILE A 1 452 ? 96.260  110.525 96.162  1.00 53.87  ? 452 ILE A HG21 1 
ATOM 6671 H HG22 . ILE A 1 452 ? 96.350  111.983 96.778  1.00 54.47  ? 452 ILE A HG22 1 
ATOM 6672 H HG23 . ILE A 1 452 ? 95.181  111.002 97.223  1.00 54.50  ? 452 ILE A HG23 1 
ATOM 6673 H HD11 . ILE A 1 452 ? 93.995  111.198 92.885  1.00 48.97  ? 452 ILE A HD11 1 
ATOM 6674 H HD12 . ILE A 1 452 ? 92.786  110.233 93.244  1.00 51.39  ? 452 ILE A HD12 1 
ATOM 6675 H HD13 . ILE A 1 452 ? 92.706  111.777 93.610  1.00 49.53  ? 452 ILE A HD13 1 
ATOM 6676 N N    . THR A 1 453 ? 93.835  113.070 98.225  1.00 53.58  ? 453 THR A N    1 
ATOM 6677 C CA   . THR A 1 453 ? 93.055  112.883 99.444  1.00 56.23  ? 453 THR A CA   1 
ATOM 6678 C C    . THR A 1 453 ? 91.750  113.669 99.376  1.00 56.56  ? 453 THR A C    1 
ATOM 6679 O O    . THR A 1 453 ? 90.675  113.140 99.679  1.00 57.18  ? 453 THR A O    1 
ATOM 6680 C CB   . THR A 1 453 ? 93.876  113.304 100.665 1.00 54.76  ? 453 THR A CB   1 
ATOM 6681 O OG1  . THR A 1 453 ? 94.802  112.266 101.003 1.00 62.07  ? 453 THR A OG1  1 
ATOM 6682 C CG2  . THR A 1 453 ? 92.968  113.572 101.857 1.00 48.78  ? 453 THR A CG2  1 
ATOM 6683 H H    . THR A 1 453 ? 94.638  113.350 98.348  1.00 54.71  ? 453 THR A H    1 
ATOM 6684 H HA   . THR A 1 453 ? 92.835  111.944 99.538  1.00 55.97  ? 453 THR A HA   1 
ATOM 6685 H HB   . THR A 1 453 ? 94.364  114.117 100.461 1.00 54.54  ? 453 THR A HB   1 
ATOM 6686 H HG1  . THR A 1 453 ? 95.235  112.478 101.692 1.00 59.67  ? 453 THR A HG1  1 
ATOM 6687 H HG21 . THR A 1 453 ? 93.485  113.544 102.676 1.00 50.88  ? 453 THR A HG21 1 
ATOM 6688 H HG22 . THR A 1 453 ? 92.557  114.447 101.776 1.00 49.56  ? 453 THR A HG22 1 
ATOM 6689 H HG23 . THR A 1 453 ? 92.273  112.896 101.906 1.00 52.36  ? 453 THR A HG23 1 
ATOM 6690 N N    . ILE A 1 454 ? 91.828  114.941 98.979  1.00 58.07  ? 454 ILE A N    1 
ATOM 6691 C CA   . ILE A 1 454 ? 90.624  115.756 98.853  1.00 56.18  ? 454 ILE A CA   1 
ATOM 6692 C C    . ILE A 1 454 ? 89.798  115.315 97.650  1.00 58.71  ? 454 ILE A C    1 
ATOM 6693 O O    . ILE A 1 454 ? 88.565  115.249 97.718  1.00 63.57  ? 454 ILE A O    1 
ATOM 6694 C CB   . ILE A 1 454 ? 91.001  117.246 98.766  1.00 57.55  ? 454 ILE A CB   1 
ATOM 6695 C CG1  . ILE A 1 454 ? 91.417  117.762 100.145 1.00 63.88  ? 454 ILE A CG1  1 
ATOM 6696 C CG2  . ILE A 1 454 ? 89.835  118.059 98.213  1.00 55.71  ? 454 ILE A CG2  1 
ATOM 6697 C CD1  . ILE A 1 454 ? 92.017  119.151 100.134 1.00 63.79  ? 454 ILE A CD1  1 
ATOM 6698 H H    . ILE A 1 454 ? 92.558  115.348 98.778  1.00 56.71  ? 454 ILE A H    1 
ATOM 6699 H HA   . ILE A 1 454 ? 90.078  115.634 99.646  1.00 56.37  ? 454 ILE A HA   1 
ATOM 6700 H HB   . ILE A 1 454 ? 91.754  117.337 98.162  1.00 58.22  ? 454 ILE A HB   1 
ATOM 6701 H HG12 . ILE A 1 454 ? 90.635  117.782 100.718 1.00 61.63  ? 454 ILE A HG12 1 
ATOM 6702 H HG13 . ILE A 1 454 ? 92.079  117.157 100.517 1.00 60.90  ? 454 ILE A HG13 1 
ATOM 6703 H HG21 . ILE A 1 454 ? 89.782  117.929 97.253  1.00 57.57  ? 454 ILE A HG21 1 
ATOM 6704 H HG22 . ILE A 1 454 ? 89.014  117.762 98.634  1.00 55.89  ? 454 ILE A HG22 1 
ATOM 6705 H HG23 . ILE A 1 454 ? 89.982  118.998 98.404  1.00 59.73  ? 454 ILE A HG23 1 
ATOM 6706 H HD11 . ILE A 1 454 ? 92.471  119.305 100.977 1.00 61.80  ? 454 ILE A HD11 1 
ATOM 6707 H HD12 . ILE A 1 454 ? 92.650  119.215 99.401  1.00 59.78  ? 454 ILE A HD12 1 
ATOM 6708 H HD13 . ILE A 1 454 ? 91.308  119.803 100.015 1.00 63.29  ? 454 ILE A HD13 1 
ATOM 6709 N N    . TYR A 1 455 ? 90.457  115.009 96.530  1.00 57.60  ? 455 TYR A N    1 
ATOM 6710 C CA   . TYR A 1 455 ? 89.724  114.749 95.295  1.00 54.51  ? 455 TYR A CA   1 
ATOM 6711 C C    . TYR A 1 455 ? 88.871  113.490 95.392  1.00 60.33  ? 455 TYR A C    1 
ATOM 6712 O O    . TYR A 1 455 ? 87.787  113.432 94.800  1.00 61.04  ? 455 TYR A O    1 
ATOM 6713 C CB   . TYR A 1 455 ? 90.701  114.633 94.122  1.00 50.93  ? 455 TYR A CB   1 
ATOM 6714 C CG   . TYR A 1 455 ? 90.071  114.736 92.743  1.00 48.88  ? 455 TYR A CG   1 
ATOM 6715 C CD1  . TYR A 1 455 ? 88.730  115.064 92.581  1.00 50.40  ? 455 TYR A CD1  1 
ATOM 6716 C CD2  . TYR A 1 455 ? 90.826  114.505 91.601  1.00 51.66  ? 455 TYR A CD2  1 
ATOM 6717 C CE1  . TYR A 1 455 ? 88.163  115.158 91.325  1.00 50.16  ? 455 TYR A CE1  1 
ATOM 6718 C CE2  . TYR A 1 455 ? 90.267  114.597 90.342  1.00 52.23  ? 455 TYR A CE2  1 
ATOM 6719 C CZ   . TYR A 1 455 ? 88.936  114.923 90.210  1.00 51.86  ? 455 TYR A CZ   1 
ATOM 6720 O OH   . TYR A 1 455 ? 88.373  115.016 88.959  1.00 50.53  ? 455 TYR A OH   1 
ATOM 6721 H H    . TYR A 1 455 ? 91.312  114.948 96.460  1.00 56.58  ? 455 TYR A H    1 
ATOM 6722 H HA   . TYR A 1 455 ? 89.134  115.500 95.134  1.00 54.87  ? 455 TYR A HA   1 
ATOM 6723 H HB2  . TYR A 1 455 ? 91.357  115.344 94.196  1.00 53.71  ? 455 TYR A HB2  1 
ATOM 6724 H HB3  . TYR A 1 455 ? 91.146  113.773 94.175  1.00 53.21  ? 455 TYR A HB3  1 
ATOM 6725 H HD1  . TYR A 1 455 ? 88.201  115.224 93.328  1.00 51.72  ? 455 TYR A HD1  1 
ATOM 6726 H HD2  . TYR A 1 455 ? 91.726  114.285 91.685  1.00 51.16  ? 455 TYR A HD2  1 
ATOM 6727 H HE1  . TYR A 1 455 ? 87.264  115.378 91.233  1.00 49.02  ? 455 TYR A HE1  1 
ATOM 6728 H HE2  . TYR A 1 455 ? 90.786  114.439 89.586  1.00 49.23  ? 455 TYR A HE2  1 
ATOM 6729 H HH   . TYR A 1 455 ? 88.948  114.845 88.371  1.00 48.96  ? 455 TYR A HH   1 
ATOM 6730 N N    . SER A 1 456 ? 89.334  112.474 96.124  1.00 60.09  ? 456 SER A N    1 
ATOM 6731 C CA   . SER A 1 456 ? 88.617  111.202 96.149  1.00 55.40  ? 456 SER A CA   1 
ATOM 6732 C C    . SER A 1 456 ? 87.210  111.362 96.712  1.00 54.43  ? 456 SER A C    1 
ATOM 6733 O O    . SER A 1 456 ? 86.249  110.804 96.169  1.00 57.06  ? 456 SER A O    1 
ATOM 6734 C CB   . SER A 1 456 ? 89.402  110.177 96.965  1.00 59.38  ? 456 SER A CB   1 
ATOM 6735 O OG   . SER A 1 456 ? 88.870  110.058 98.272  1.00 63.70  ? 456 SER A OG   1 
ATOM 6736 H H    . SER A 1 456 ? 90.046  112.497 96.605  1.00 57.21  ? 456 SER A H    1 
ATOM 6737 H HA   . SER A 1 456 ? 88.539  110.867 95.242  1.00 56.36  ? 456 SER A HA   1 
ATOM 6738 H HB2  . SER A 1 456 ? 89.347  109.316 96.523  1.00 59.84  ? 456 SER A HB2  1 
ATOM 6739 H HB3  . SER A 1 456 ? 90.328  110.460 97.024  1.00 57.67  ? 456 SER A HB3  1 
ATOM 6740 H HG   . SER A 1 456 ? 89.292  109.472 98.702  1.00 61.75  ? 456 SER A HG   1 
ATOM 6741 N N    . GLY A 1 457 ? 87.065  112.117 97.802  1.00 53.04  ? 457 GLY A N    1 
ATOM 6742 C CA   . GLY A 1 457 ? 85.764  112.228 98.442  1.00 58.00  ? 457 GLY A CA   1 
ATOM 6743 C C    . GLY A 1 457 ? 84.731  112.922 97.574  1.00 59.35  ? 457 GLY A C    1 
ATOM 6744 O O    . GLY A 1 457 ? 83.550  112.566 97.594  1.00 62.69  ? 457 GLY A O    1 
ATOM 6745 H H    . GLY A 1 457 ? 87.694  112.565 98.182  1.00 56.03  ? 457 GLY A H    1 
ATOM 6746 H HA2  . GLY A 1 457 ? 85.434  111.342 98.657  1.00 57.01  ? 457 GLY A HA2  1 
ATOM 6747 H HA3  . GLY A 1 457 ? 85.853  112.729 99.268  1.00 58.22  ? 457 GLY A HA3  1 
ATOM 6748 N N    . GLU A 1 458 ? 85.158  113.922 96.801  1.00 57.53  ? 458 GLU A N    1 
ATOM 6749 C CA   . GLU A 1 458 ? 84.205  114.723 96.039  1.00 64.07  ? 458 GLU A CA   1 
ATOM 6750 C C    . GLU A 1 458 ? 83.566  113.929 94.906  1.00 64.24  ? 458 GLU A C    1 
ATOM 6751 O O    . GLU A 1 458 ? 82.433  114.224 94.509  1.00 60.79  ? 458 GLU A O    1 
ATOM 6752 C CB   . GLU A 1 458 ? 84.888  115.974 95.479  1.00 66.99  ? 458 GLU A CB   1 
ATOM 6753 C CG   . GLU A 1 458 ? 85.979  116.559 96.367  1.00 72.63  ? 458 GLU A CG   1 
ATOM 6754 C CD   . GLU A 1 458 ? 85.979  118.075 96.367  1.00 78.15  ? 458 GLU A CD   1 
ATOM 6755 O OE1  . GLU A 1 458 ? 85.970  118.670 97.465  1.00 70.34  ? 458 GLU A OE1  1 
ATOM 6756 O OE2  . GLU A 1 458 ? 85.987  118.671 95.270  1.00 77.76  ? 458 GLU A OE2  1 
ATOM 6757 H H    . GLU A 1 458 ? 85.982  114.143 96.698  1.00 59.87  ? 458 GLU A H    1 
ATOM 6758 H HA   . GLU A 1 458 ? 83.496  115.014 96.634  1.00 64.11  ? 458 GLU A HA   1 
ATOM 6759 H HB2  . GLU A 1 458 ? 85.294  115.749 94.628  1.00 64.73  ? 458 GLU A HB2  1 
ATOM 6760 H HB3  . GLU A 1 458 ? 84.216  116.662 95.348  1.00 66.10  ? 458 GLU A HB3  1 
ATOM 6761 H HG2  . GLU A 1 458 ? 85.841  116.266 97.281  1.00 71.10  ? 458 GLU A HG2  1 
ATOM 6762 H HG3  . GLU A 1 458 ? 86.843  116.257 96.047  1.00 68.40  ? 458 GLU A HG3  1 
ATOM 6763 N N    . LEU A 1 459 ? 84.267  112.926 94.375  1.00 59.98  ? 459 LEU A N    1 
ATOM 6764 C CA   . LEU A 1 459 ? 83.779  112.229 93.189  1.00 57.56  ? 459 LEU A CA   1 
ATOM 6765 C C    . LEU A 1 459 ? 82.455  111.524 93.460  1.00 65.44  ? 459 LEU A C    1 
ATOM 6766 O O    . LEU A 1 459 ? 81.486  111.690 92.711  1.00 74.51  ? 459 LEU A O    1 
ATOM 6767 C CB   . LEU A 1 459 ? 84.826  111.223 92.709  1.00 54.30  ? 459 LEU A CB   1 
ATOM 6768 C CG   . LEU A 1 459 ? 86.055  111.811 92.016  1.00 51.07  ? 459 LEU A CG   1 
ATOM 6769 C CD1  . LEU A 1 459 ? 87.224  110.847 92.112  1.00 51.23  ? 459 LEU A CD1  1 
ATOM 6770 C CD2  . LEU A 1 459 ? 85.748  112.141 90.567  1.00 53.29  ? 459 LEU A CD2  1 
ATOM 6771 H H    . LEU A 1 459 ? 85.017  112.635 94.678  1.00 59.21  ? 459 LEU A H    1 
ATOM 6772 H HA   . LEU A 1 459 ? 83.636  112.875 92.480  1.00 58.94  ? 459 LEU A HA   1 
ATOM 6773 H HB2  . LEU A 1 459 ? 85.139  110.721 93.478  1.00 57.30  ? 459 LEU A HB2  1 
ATOM 6774 H HB3  . LEU A 1 459 ? 84.401  110.619 92.081  1.00 55.90  ? 459 LEU A HB3  1 
ATOM 6775 H HG   . LEU A 1 459 ? 86.307  112.634 92.464  1.00 54.62  ? 459 LEU A HG   1 
ATOM 6776 H HD11 . LEU A 1 459 ? 87.439  110.704 93.047  1.00 52.72  ? 459 LEU A HD11 1 
ATOM 6777 H HD12 . LEU A 1 459 ? 86.974  110.007 91.697  1.00 52.62  ? 459 LEU A HD12 1 
ATOM 6778 H HD13 . LEU A 1 459 ? 87.987  111.230 91.651  1.00 52.80  ? 459 LEU A HD13 1 
ATOM 6779 H HD21 . LEU A 1 459 ? 84.913  112.632 90.525  1.00 54.16  ? 459 LEU A HD21 1 
ATOM 6780 H HD22 . LEU A 1 459 ? 86.468  112.681 90.206  1.00 53.36  ? 459 LEU A HD22 1 
ATOM 6781 H HD23 . LEU A 1 459 ? 85.670  111.314 90.065  1.00 53.99  ? 459 LEU A HD23 1 
ATOM 6782 N N    . PHE A 1 460 ? 82.395  110.738 94.526  1.00 64.22  ? 460 PHE A N    1 
ATOM 6783 C CA   . PHE A 1 460 ? 81.283  109.832 94.763  1.00 63.92  ? 460 PHE A CA   1 
ATOM 6784 C C    . PHE A 1 460 ? 80.187  110.504 95.577  1.00 70.44  ? 460 PHE A C    1 
ATOM 6785 O O    . PHE A 1 460 ? 80.413  111.533 96.221  1.00 77.34  ? 460 PHE A O    1 
ATOM 6786 C CB   . PHE A 1 460 ? 81.777  108.588 95.494  1.00 58.41  ? 460 PHE A CB   1 
ATOM 6787 C CG   . PHE A 1 460 ? 83.085  108.071 94.979  1.00 58.21  ? 460 PHE A CG   1 
ATOM 6788 C CD1  . PHE A 1 460 ? 83.138  107.314 93.824  1.00 60.47  ? 460 PHE A CD1  1 
ATOM 6789 C CD2  . PHE A 1 460 ? 84.266  108.360 95.639  1.00 57.01  ? 460 PHE A CD2  1 
ATOM 6790 C CE1  . PHE A 1 460 ? 84.343  106.842 93.344  1.00 61.57  ? 460 PHE A CE1  1 
ATOM 6791 C CE2  . PHE A 1 460 ? 85.474  107.894 95.163  1.00 61.52  ? 460 PHE A CE2  1 
ATOM 6792 C CZ   . PHE A 1 460 ? 85.512  107.133 94.015  1.00 62.18  ? 460 PHE A CZ   1 
ATOM 6793 H H    . PHE A 1 460 ? 82.999  110.713 95.138  1.00 61.98  ? 460 PHE A H    1 
ATOM 6794 H HA   . PHE A 1 460 ? 80.916  109.559 93.909  1.00 63.71  ? 460 PHE A HA   1 
ATOM 6795 H HB2  . PHE A 1 460 ? 81.891  108.802 96.433  1.00 59.05  ? 460 PHE A HB2  1 
ATOM 6796 H HB3  . PHE A 1 460 ? 81.118  107.884 95.393  1.00 62.35  ? 460 PHE A HB3  1 
ATOM 6797 H HD1  . PHE A 1 460 ? 82.352  107.115 93.368  1.00 60.40  ? 460 PHE A HD1  1 
ATOM 6798 H HD2  . PHE A 1 460 ? 84.244  108.872 96.416  1.00 58.20  ? 460 PHE A HD2  1 
ATOM 6799 H HE1  . PHE A 1 460 ? 84.366  106.331 92.568  1.00 60.08  ? 460 PHE A HE1  1 
ATOM 6800 H HE2  . PHE A 1 460 ? 86.260  108.090 95.618  1.00 60.06  ? 460 PHE A HE2  1 
ATOM 6801 H HZ   . PHE A 1 460 ? 86.325  106.817 93.692  1.00 59.72  ? 460 PHE A HZ   1 
ATOM 6802 N N    . PRO A 1 461 ? 78.978  109.942 95.568  1.00 71.14  ? 461 PRO A N    1 
ATOM 6803 C CA   . PRO A 1 461 ? 77.904  110.486 96.407  1.00 74.94  ? 461 PRO A CA   1 
ATOM 6804 C C    . PRO A 1 461 ? 78.278  110.454 97.881  1.00 76.36  ? 461 PRO A C    1 
ATOM 6805 O O    . PRO A 1 461 ? 79.290  109.883 98.293  1.00 73.43  ? 461 PRO A O    1 
ATOM 6806 C CB   . PRO A 1 461 ? 76.713  109.568 96.109  1.00 62.60  ? 461 PRO A CB   1 
ATOM 6807 C CG   . PRO A 1 461 ? 77.007  108.973 94.781  1.00 58.68  ? 461 PRO A CG   1 
ATOM 6808 C CD   . PRO A 1 461 ? 78.499  108.863 94.687  1.00 63.19  ? 461 PRO A CD   1 
ATOM 6809 H HA   . PRO A 1 461 ? 77.688  111.394 96.142  1.00 73.86  ? 461 PRO A HA   1 
ATOM 6810 H HB2  . PRO A 1 461 ? 76.653  108.879 96.789  1.00 64.44  ? 461 PRO A HB2  1 
ATOM 6811 H HB3  . PRO A 1 461 ? 75.897  110.091 96.078  1.00 64.50  ? 461 PRO A HB3  1 
ATOM 6812 H HG2  . PRO A 1 461 ? 76.597  108.096 94.722  1.00 62.44  ? 461 PRO A HG2  1 
ATOM 6813 H HG3  . PRO A 1 461 ? 76.665  109.554 94.084  1.00 61.25  ? 461 PRO A HG3  1 
ATOM 6814 H HD2  . PRO A 1 461 ? 78.798  108.000 95.012  1.00 66.07  ? 461 PRO A HD2  1 
ATOM 6815 H HD3  . PRO A 1 461 ? 78.783  109.019 93.773  1.00 64.33  ? 461 PRO A HD3  1 
ATOM 6816 N N    . THR A 1 462 ? 77.426  111.085 98.690  1.00 76.59  ? 462 THR A N    1 
ATOM 6817 C CA   . THR A 1 462 ? 77.696  111.170 100.122 1.00 78.08  ? 462 THR A CA   1 
ATOM 6818 C C    . THR A 1 462 ? 77.645  109.795 100.778 1.00 78.55  ? 462 THR A C    1 
ATOM 6819 O O    . THR A 1 462 ? 78.456  109.492 101.661 1.00 78.17  ? 462 THR A O    1 
ATOM 6820 C CB   . THR A 1 462 ? 76.703  112.116 100.806 1.00 81.67  ? 462 THR A CB   1 
ATOM 6821 O OG1  . THR A 1 462 ? 75.535  111.384 101.201 1.00 83.42  ? 462 THR A OG1  1 
ATOM 6822 C CG2  . THR A 1 462 ? 76.304  113.275 99.893  1.00 83.93  ? 462 THR A CG2  1 
ATOM 6823 H H    . THR A 1 462 ? 76.693  111.448 98.430  1.00 74.89  ? 462 THR A H    1 
ATOM 6824 H HA   . THR A 1 462 ? 78.587  111.529 100.251 1.00 78.08  ? 462 THR A HA   1 
ATOM 6825 H HB   . THR A 1 462 ? 77.120  112.490 101.597 1.00 80.51  ? 462 THR A HB   1 
ATOM 6826 H HG1  . THR A 1 462 ? 74.995  111.894 101.594 1.00 83.81  ? 462 THR A HG1  1 
ATOM 6827 H HG21 . THR A 1 462 ? 75.908  113.987 100.419 1.00 83.72  ? 462 THR A HG21 1 
ATOM 6828 H HG22 . THR A 1 462 ? 77.086  113.621 99.435  1.00 82.53  ? 462 THR A HG22 1 
ATOM 6829 H HG23 . THR A 1 462 ? 75.658  112.977 99.234  1.00 80.04  ? 462 THR A HG23 1 
ATOM 6830 N N    . VAL A 1 463 ? 76.698  108.952 100.365 1.00 79.12  ? 463 VAL A N    1 
ATOM 6831 C CA   . VAL A 1 463 ? 76.507  107.669 101.034 1.00 77.23  ? 463 VAL A CA   1 
ATOM 6832 C C    . VAL A 1 463 ? 77.689  106.740 100.776 1.00 74.53  ? 463 VAL A C    1 
ATOM 6833 O O    . VAL A 1 463 ? 78.117  105.999 101.669 1.00 82.41  ? 463 VAL A O    1 
ATOM 6834 C CB   . VAL A 1 463 ? 75.175  107.030 100.594 1.00 72.98  ? 463 VAL A CB   1 
ATOM 6835 C CG1  . VAL A 1 463 ? 75.111  106.876 99.076  1.00 75.23  ? 463 VAL A CG1  1 
ATOM 6836 C CG2  . VAL A 1 463 ? 74.972  105.688 101.285 1.00 70.72  ? 463 VAL A CG2  1 
ATOM 6837 H H    . VAL A 1 463 ? 76.161  109.103 99.711  1.00 77.77  ? 463 VAL A H    1 
ATOM 6838 H HA   . VAL A 1 463 ? 76.457  107.823 101.991 1.00 79.28  ? 463 VAL A HA   1 
ATOM 6839 H HB   . VAL A 1 463 ? 74.447  107.613 100.862 1.00 74.35  ? 463 VAL A HB   1 
ATOM 6840 H HG11 . VAL A 1 463 ? 74.293  106.409 98.845  1.00 73.75  ? 463 VAL A HG11 1 
ATOM 6841 H HG12 . VAL A 1 463 ? 75.113  107.753 98.663  1.00 75.94  ? 463 VAL A HG12 1 
ATOM 6842 H HG13 . VAL A 1 463 ? 75.876  106.364 98.773  1.00 75.41  ? 463 VAL A HG13 1 
ATOM 6843 H HG21 . VAL A 1 463 ? 75.584  105.619 102.034 1.00 73.35  ? 463 VAL A HG21 1 
ATOM 6844 H HG22 . VAL A 1 463 ? 74.057  105.635 101.603 1.00 70.69  ? 463 VAL A HG22 1 
ATOM 6845 H HG23 . VAL A 1 463 ? 75.141  104.976 100.649 1.00 74.76  ? 463 VAL A HG23 1 
ATOM 6846 N N    . LEU A 1 464 ? 78.235  106.761 99.561  1.00 68.27  ? 464 LEU A N    1 
ATOM 6847 C CA   . LEU A 1 464 ? 79.273  105.822 99.154  1.00 60.67  ? 464 LEU A CA   1 
ATOM 6848 C C    . LEU A 1 464 ? 80.685  106.375 99.304  1.00 63.69  ? 464 LEU A C    1 
ATOM 6849 O O    . LEU A 1 464 ? 81.641  105.706 98.900  1.00 67.40  ? 464 LEU A O    1 
ATOM 6850 C CB   . LEU A 1 464 ? 79.046  105.391 97.701  1.00 42.92  ? 464 LEU A CB   1 
ATOM 6851 H H    . LEU A 1 464 ? 78.016  107.320 98.946  1.00 69.94  ? 464 LEU A H    1 
ATOM 6852 H HA   . LEU A 1 464 ? 79.209  105.028 99.709  1.00 64.65  ? 464 LEU A HA   1 
ATOM 6853 N N    . ARG A 1 465 ? 80.844  107.575 99.866  1.00 67.85  ? 465 ARG A N    1 
ATOM 6854 C CA   . ARG A 1 465 ? 82.174  108.171 99.968  1.00 72.45  ? 465 ARG A CA   1 
ATOM 6855 C C    . ARG A 1 465 ? 83.081  107.370 100.897 1.00 75.04  ? 465 ARG A C    1 
ATOM 6856 O O    . ARG A 1 465 ? 84.261  107.160 100.589 1.00 74.24  ? 465 ARG A O    1 
ATOM 6857 C CB   . ARG A 1 465 ? 82.059  109.618 100.450 1.00 69.97  ? 465 ARG A CB   1 
ATOM 6858 C CG   . ARG A 1 465 ? 83.390  110.240 100.865 1.00 69.38  ? 465 ARG A CG   1 
ATOM 6859 C CD   . ARG A 1 465 ? 83.299  111.750 101.084 1.00 73.19  ? 465 ARG A CD   1 
ATOM 6860 N NE   . ARG A 1 465 ? 82.428  112.417 100.122 1.00 78.79  ? 465 ARG A NE   1 
ATOM 6861 C CZ   . ARG A 1 465 ? 81.163  112.749 100.346 1.00 78.83  ? 465 ARG A CZ   1 
ATOM 6862 N NH1  . ARG A 1 465 ? 80.572  112.494 101.503 1.00 79.77  ? 465 ARG A NH1  1 
ATOM 6863 N NH2  . ARG A 1 465 ? 80.471  113.352 99.383  1.00 73.38  ? 465 ARG A NH2  1 
ATOM 6864 H H    . ARG A 1 465 ? 80.210  108.056 100.192 1.00 70.08  ? 465 ARG A H    1 
ATOM 6865 H HA   . ARG A 1 465 ? 82.581  108.181 99.089  1.00 70.51  ? 465 ARG A HA   1 
ATOM 6866 H HB2  . ARG A 1 465 ? 81.687  110.144 99.726  1.00 70.44  ? 465 ARG A HB2  1 
ATOM 6867 H HB3  . ARG A 1 465 ? 81.466  109.647 101.217 1.00 71.90  ? 465 ARG A HB3  1 
ATOM 6868 H HG2  . ARG A 1 465 ? 83.681  109.841 101.700 1.00 69.80  ? 465 ARG A HG2  1 
ATOM 6869 H HG3  . ARG A 1 465 ? 84.047  110.076 100.171 1.00 69.15  ? 465 ARG A HG3  1 
ATOM 6870 H HD2  . ARG A 1 465 ? 82.968  111.922 101.978 1.00 73.22  ? 465 ARG A HD2  1 
ATOM 6871 H HD3  . ARG A 1 465 ? 84.186  112.129 100.987 1.00 70.73  ? 465 ARG A HD3  1 
ATOM 6872 H HE   . ARG A 1 465 ? 82.770  112.643 99.366  1.00 73.26  ? 465 ARG A HE   1 
ATOM 6873 H HH11 . ARG A 1 465 ? 81.002  112.104 102.136 1.00 78.38  ? 465 ARG A HH11 1 
ATOM 6874 H HH12 . ARG A 1 465 ? 79.750  112.719 101.621 1.00 78.31  ? 465 ARG A HH12 1 
ATOM 6875 H HH21 . ARG A 1 465 ? 80.844  113.522 98.628  1.00 72.34  ? 465 ARG A HH21 1 
ATOM 6876 H HH22 . ARG A 1 465 ? 79.650  113.571 99.517  1.00 75.30  ? 465 ARG A HH22 1 
ATOM 6877 N N    . MET A 1 466 ? 82.556  106.926 102.043 1.00 77.44  ? 466 MET A N    1 
ATOM 6878 C CA   . MET A 1 466 ? 83.398  106.260 103.034 1.00 79.57  ? 466 MET A CA   1 
ATOM 6879 C C    . MET A 1 466 ? 83.984  104.963 102.489 1.00 75.21  ? 466 MET A C    1 
ATOM 6880 O O    . MET A 1 466 ? 85.165  104.666 102.710 1.00 72.49  ? 466 MET A O    1 
ATOM 6881 C CB   . MET A 1 466 ? 82.593  105.986 104.306 1.00 83.22  ? 466 MET A CB   1 
ATOM 6882 C CG   . MET A 1 466 ? 83.429  105.967 105.579 1.00 85.46  ? 466 MET A CG   1 
ATOM 6883 S SD   . MET A 1 466 ? 82.646  106.830 106.956 1.00 124.68 ? 466 MET A SD   1 
ATOM 6884 C CE   . MET A 1 466 ? 83.624  106.224 108.331 1.00 83.95  ? 466 MET A CE   1 
ATOM 6885 H H    . MET A 1 466 ? 81.729  106.999 102.267 1.00 76.59  ? 466 MET A H    1 
ATOM 6886 H HA   . MET A 1 466 ? 84.127  106.855 103.266 1.00 78.89  ? 466 MET A HA   1 
ATOM 6887 H HB2  . MET A 1 466 ? 81.920  106.677 104.404 1.00 83.09  ? 466 MET A HB2  1 
ATOM 6888 H HB3  . MET A 1 466 ? 82.163  105.120 104.222 1.00 83.69  ? 466 MET A HB3  1 
ATOM 6889 H HG2  . MET A 1 466 ? 83.570  105.046 105.848 1.00 86.26  ? 466 MET A HG2  1 
ATOM 6890 H HG3  . MET A 1 466 ? 84.283  106.395 105.409 1.00 83.47  ? 466 MET A HG3  1 
ATOM 6891 H HE1  . MET A 1 466 ? 83.296  106.623 109.152 1.00 91.61  ? 466 MET A HE1  1 
ATOM 6892 H HE2  . MET A 1 466 ? 83.541  105.258 108.376 1.00 82.08  ? 466 MET A HE2  1 
ATOM 6893 H HE3  . MET A 1 466 ? 84.552  106.470 108.191 1.00 83.51  ? 466 MET A HE3  1 
ATOM 6894 N N    . THR A 1 467 ? 83.175  104.171 101.782 1.00 67.64  ? 467 THR A N    1 
ATOM 6895 C CA   . THR A 1 467 ? 83.672  102.910 101.240 1.00 65.09  ? 467 THR A CA   1 
ATOM 6896 C C    . THR A 1 467 ? 84.782  103.151 100.226 1.00 62.39  ? 467 THR A C    1 
ATOM 6897 O O    . THR A 1 467 ? 85.806  102.457 100.237 1.00 62.78  ? 467 THR A O    1 
ATOM 6898 C CB   . THR A 1 467 ? 82.535  102.116 100.596 1.00 67.00  ? 467 THR A CB   1 
ATOM 6899 O OG1  . THR A 1 467 ? 82.255  102.648 99.295  1.00 75.13  ? 467 THR A OG1  1 
ATOM 6900 C CG2  . THR A 1 467 ? 81.271  102.158 101.450 1.00 72.44  ? 467 THR A CG2  1 
ATOM 6901 H H    . THR A 1 467 ? 82.355  104.351 101.600 1.00 70.15  ? 467 THR A H    1 
ATOM 6902 H HA   . THR A 1 467 ? 84.038  102.377 101.964 1.00 68.91  ? 467 THR A HA   1 
ATOM 6903 H HB   . THR A 1 467 ? 82.806  101.189 100.506 1.00 70.27  ? 467 THR A HB   1 
ATOM 6904 H HG1  . THR A 1 467 ? 81.587  102.261 98.964  1.00 73.23  ? 467 THR A HG1  1 
ATOM 6905 H HG21 . THR A 1 467 ? 80.626  101.522 101.107 1.00 80.24  ? 467 THR A HG21 1 
ATOM 6906 H HG22 . THR A 1 467 ? 81.482  101.930 102.369 1.00 77.30  ? 467 THR A HG22 1 
ATOM 6907 H HG23 . THR A 1 467 ? 80.875  103.043 101.427 1.00 73.07  ? 467 THR A HG23 1 
ATOM 6908 N N    . ALA A 1 468 ? 84.598  104.133 99.341  1.00 59.62  ? 468 ALA A N    1 
ATOM 6909 C CA   . ALA A 1 468 ? 85.625  104.438 98.351  1.00 62.16  ? 468 ALA A CA   1 
ATOM 6910 C C    . ALA A 1 468 ? 86.900  104.935 99.018  1.00 63.35  ? 468 ALA A C    1 
ATOM 6911 O O    . ALA A 1 468 ? 88.007  104.560 98.611  1.00 66.05  ? 468 ALA A O    1 
ATOM 6912 C CB   . ALA A 1 468 ? 85.102  105.473 97.358  1.00 56.54  ? 468 ALA A CB   1 
ATOM 6913 H H    . ALA A 1 468 ? 83.897  104.630 99.295  1.00 64.29  ? 468 ALA A H    1 
ATOM 6914 H HA   . ALA A 1 468 ? 85.838  103.631 97.859  1.00 64.99  ? 468 ALA A HA   1 
ATOM 6915 H HB1  . ALA A 1 468 ? 84.306  105.124 96.926  1.00 60.65  ? 468 ALA A HB1  1 
ATOM 6916 H HB2  . ALA A 1 468 ? 84.888  106.290 97.836  1.00 61.64  ? 468 ALA A HB2  1 
ATOM 6917 H HB3  . ALA A 1 468 ? 85.789  105.646 96.696  1.00 57.75  ? 468 ALA A HB3  1 
ATOM 6918 N N    . VAL A 1 469 ? 86.768  105.781 100.041 1.00 62.32  ? 469 VAL A N    1 
ATOM 6919 C CA   . VAL A 1 469 ? 87.951  106.266 100.745 1.00 65.42  ? 469 VAL A CA   1 
ATOM 6920 C C    . VAL A 1 469 ? 88.694  105.105 101.391 1.00 72.95  ? 469 VAL A C    1 
ATOM 6921 O O    . VAL A 1 469 ? 89.923  105.008 101.298 1.00 74.79  ? 469 VAL A O    1 
ATOM 6922 C CB   . VAL A 1 469 ? 87.558  107.335 101.782 1.00 64.96  ? 469 VAL A CB   1 
ATOM 6923 C CG1  . VAL A 1 469 ? 88.741  107.658 102.684 1.00 67.50  ? 469 VAL A CG1  1 
ATOM 6924 C CG2  . VAL A 1 469 ? 87.051  108.590 101.083 1.00 66.71  ? 469 VAL A CG2  1 
ATOM 6925 H H    . VAL A 1 469 ? 86.020  106.084 100.339 1.00 65.58  ? 469 VAL A H    1 
ATOM 6926 H HA   . VAL A 1 469 ? 88.548  106.681 100.103 1.00 65.48  ? 469 VAL A HA   1 
ATOM 6927 H HB   . VAL A 1 469 ? 86.841  106.989 102.337 1.00 67.35  ? 469 VAL A HB   1 
ATOM 6928 H HG11 . VAL A 1 469 ? 89.564  107.561 102.179 1.00 66.84  ? 469 VAL A HG11 1 
ATOM 6929 H HG12 . VAL A 1 469 ? 88.657  108.569 103.007 1.00 67.75  ? 469 VAL A HG12 1 
ATOM 6930 H HG13 . VAL A 1 469 ? 88.738  107.045 103.436 1.00 67.54  ? 469 VAL A HG13 1 
ATOM 6931 H HG21 . VAL A 1 469 ? 86.911  108.394 100.144 1.00 64.62  ? 469 VAL A HG21 1 
ATOM 6932 H HG22 . VAL A 1 469 ? 86.215  108.862 101.492 1.00 68.14  ? 469 VAL A HG22 1 
ATOM 6933 H HG23 . VAL A 1 469 ? 87.709  109.296 101.178 1.00 66.28  ? 469 VAL A HG23 1 
ATOM 6934 N N    . GLY A 1 470 ? 87.963  104.204 102.051 1.00 70.94  ? 470 GLY A N    1 
ATOM 6935 C CA   . GLY A 1 470 ? 88.612  103.060 102.671 1.00 66.62  ? 470 GLY A CA   1 
ATOM 6936 C C    . GLY A 1 470 ? 89.302  102.169 101.656 1.00 63.28  ? 470 GLY A C    1 
ATOM 6937 O O    . GLY A 1 470 ? 90.409  101.679 101.895 1.00 65.55  ? 470 GLY A O    1 
ATOM 6938 H H    . GLY A 1 470 ? 87.110  104.235 102.151 1.00 68.83  ? 470 GLY A H    1 
ATOM 6939 H HA2  . GLY A 1 470 ? 89.273  103.371 103.309 1.00 67.62  ? 470 GLY A HA2  1 
ATOM 6940 H HA3  . GLY A 1 470 ? 87.951  102.533 103.146 1.00 66.62  ? 470 GLY A HA3  1 
ATOM 6941 N N    . LEU A 1 471 ? 88.655  101.947 100.510 1.00 56.49  ? 471 LEU A N    1 
ATOM 6942 C CA   . LEU A 1 471 ? 89.272  101.156 99.452  1.00 52.34  ? 471 LEU A CA   1 
ATOM 6943 C C    . LEU A 1 471 ? 90.562  101.806 98.971  1.00 56.12  ? 471 LEU A C    1 
ATOM 6944 O O    . LEU A 1 471 ? 91.574  101.124 98.763  1.00 60.99  ? 471 LEU A O    1 
ATOM 6945 C CB   . LEU A 1 471 ? 88.289  100.990 98.294  1.00 51.24  ? 471 LEU A CB   1 
ATOM 6946 C CG   . LEU A 1 471 ? 88.645  99.969  97.214  1.00 60.25  ? 471 LEU A CG   1 
ATOM 6947 C CD1  . LEU A 1 471 ? 88.482  98.557  97.743  1.00 65.54  ? 471 LEU A CD1  1 
ATOM 6948 C CD2  . LEU A 1 471 ? 87.786  100.183 95.976  1.00 59.70  ? 471 LEU A CD2  1 
ATOM 6949 H H    . LEU A 1 471 ? 87.869  102.242 100.325 1.00 60.38  ? 471 LEU A H    1 
ATOM 6950 H HA   . LEU A 1 471 ? 89.487  100.275 99.797  1.00 56.28  ? 471 LEU A HA   1 
ATOM 6951 H HB2  . LEU A 1 471 ? 87.431  100.729 98.663  1.00 56.60  ? 471 LEU A HB2  1 
ATOM 6952 H HB3  . LEU A 1 471 ? 88.196  101.850 97.854  1.00 56.39  ? 471 LEU A HB3  1 
ATOM 6953 H HG   . LEU A 1 471 ? 89.573  100.090 96.959  1.00 59.51  ? 471 LEU A HG   1 
ATOM 6954 H HD11 . LEU A 1 471 ? 88.664  97.930  97.025  1.00 63.42  ? 471 LEU A HD11 1 
ATOM 6955 H HD12 . LEU A 1 471 ? 89.108  98.418  98.471  1.00 63.44  ? 471 LEU A HD12 1 
ATOM 6956 H HD13 . LEU A 1 471 ? 87.573  98.443  98.060  1.00 64.91  ? 471 LEU A HD13 1 
ATOM 6957 H HD21 . LEU A 1 471 ? 88.025  99.522  95.308  1.00 60.76  ? 471 LEU A HD21 1 
ATOM 6958 H HD22 . LEU A 1 471 ? 86.852  100.087 96.219  1.00 60.71  ? 471 LEU A HD22 1 
ATOM 6959 H HD23 . LEU A 1 471 ? 87.947  101.076 95.631  1.00 57.50  ? 471 LEU A HD23 1 
ATOM 6960 N N    . GLY A 1 472 ? 90.546  103.128 98.794  1.00 54.76  ? 472 GLY A N    1 
ATOM 6961 C CA   . GLY A 1 472 ? 91.755  103.823 98.388  1.00 53.22  ? 472 GLY A CA   1 
ATOM 6962 C C    . GLY A 1 472 ? 92.871  103.693 99.407  1.00 55.81  ? 472 GLY A C    1 
ATOM 6963 O O    . GLY A 1 472 ? 94.029  103.469 99.048  1.00 65.59  ? 472 GLY A O    1 
ATOM 6964 H H    . GLY A 1 472 ? 89.858  103.633 98.904  1.00 59.06  ? 472 GLY A H    1 
ATOM 6965 H HA2  . GLY A 1 472 ? 92.065  103.464 97.542  1.00 55.97  ? 472 GLY A HA2  1 
ATOM 6966 H HA3  . GLY A 1 472 ? 91.560  104.765 98.268  1.00 55.91  ? 472 GLY A HA3  1 
ATOM 6967 N N    . GLN A 1 473 ? 92.539  103.838 100.692 1.00 54.44  ? 473 GLN A N    1 
ATOM 6968 C CA   . GLN A 1 473 ? 93.559  103.708 101.732 1.00 58.88  ? 473 GLN A CA   1 
ATOM 6969 C C    . GLN A 1 473 ? 94.148  102.303 101.750 1.00 57.63  ? 473 GLN A C    1 
ATOM 6970 O O    . GLN A 1 473 ? 95.369  102.133 101.869 1.00 57.66  ? 473 GLN A O    1 
ATOM 6971 C CB   . GLN A 1 473 ? 92.977  104.057 103.106 1.00 65.27  ? 473 GLN A CB   1 
ATOM 6972 C CG   . GLN A 1 473 ? 92.065  105.277 103.148 1.00 67.14  ? 473 GLN A CG   1 
ATOM 6973 C CD   . GLN A 1 473 ? 92.741  106.504 103.715 1.00 77.97  ? 473 GLN A CD   1 
ATOM 6974 O OE1  . GLN A 1 473 ? 93.943  106.704 103.546 1.00 87.34  ? 473 GLN A OE1  1 
ATOM 6975 N NE2  . GLN A 1 473 ? 91.962  107.344 104.384 1.00 77.49  ? 473 GLN A NE2  1 
ATOM 6976 H H    . GLN A 1 473 ? 91.745  103.997 100.979 1.00 59.50  ? 473 GLN A H    1 
ATOM 6977 H HA   . GLN A 1 473 ? 94.280  104.330 101.549 1.00 60.70  ? 473 GLN A HA   1 
ATOM 6978 H HB2  . GLN A 1 473 ? 92.459  103.300 103.418 1.00 64.34  ? 473 GLN A HB2  1 
ATOM 6979 H HB3  . GLN A 1 473 ? 93.710  104.223 103.719 1.00 67.01  ? 473 GLN A HB3  1 
ATOM 6980 H HG2  . GLN A 1 473 ? 91.808  105.520 102.252 1.00 66.30  ? 473 GLN A HG2  1 
ATOM 6981 H HG3  . GLN A 1 473 ? 91.282  105.078 103.685 1.00 67.18  ? 473 GLN A HG3  1 
ATOM 6982 H HE21 . GLN A 1 473 ? 91.125  107.171 104.477 1.00 70.65  ? 473 GLN A HE21 1 
ATOM 6983 H HE22 . GLN A 1 473 ? 92.294  108.059 104.726 1.00 74.43  ? 473 GLN A HE22 1 
ATOM 6984 N N    . MET A 1 474 ? 93.297  101.281 101.633 1.00 54.93  ? 474 MET A N    1 
ATOM 6985 C CA   . MET A 1 474 ? 93.801  99.912  101.608 1.00 54.20  ? 474 MET A CA   1 
ATOM 6986 C C    . MET A 1 474 ? 94.705  99.684  100.403 1.00 55.44  ? 474 MET A C    1 
ATOM 6987 O O    . MET A 1 474 ? 95.752  99.037  100.517 1.00 54.75  ? 474 MET A O    1 
ATOM 6988 C CB   . MET A 1 474 ? 92.639  98.918  101.592 1.00 51.19  ? 474 MET A CB   1 
ATOM 6989 C CG   . MET A 1 474 ? 91.788  98.881  102.862 1.00 57.21  ? 474 MET A CG   1 
ATOM 6990 S SD   . MET A 1 474 ? 92.662  99.292  104.385 1.00 66.08  ? 474 MET A SD   1 
ATOM 6991 C CE   . MET A 1 474 ? 92.666  97.701  105.209 1.00 58.68  ? 474 MET A CE   1 
ATOM 6992 H H    . MET A 1 474 ? 92.442  101.352 101.566 1.00 57.35  ? 474 MET A H    1 
ATOM 6993 H HA   . MET A 1 474 ? 94.330  99.756  102.404 1.00 55.06  ? 474 MET A HA   1 
ATOM 6994 H HB2  . MET A 1 474 ? 92.051  99.147  100.856 1.00 55.06  ? 474 MET A HB2  1 
ATOM 6995 H HB3  . MET A 1 474 ? 92.997  98.028  101.456 1.00 52.38  ? 474 MET A HB3  1 
ATOM 6996 H HG2  . MET A 1 474 ? 91.057  99.511  102.764 1.00 58.85  ? 474 MET A HG2  1 
ATOM 6997 H HG3  . MET A 1 474 ? 91.432  97.984  102.963 1.00 58.06  ? 474 MET A HG3  1 
ATOM 6998 H HE1  . MET A 1 474 ? 93.120  97.788  106.062 1.00 54.08  ? 474 MET A HE1  1 
ATOM 6999 H HE2  . MET A 1 474 ? 91.750  97.415  105.350 1.00 57.04  ? 474 MET A HE2  1 
ATOM 7000 H HE3  . MET A 1 474 ? 93.132  97.057  104.652 1.00 55.84  ? 474 MET A HE3  1 
ATOM 7001 N N    . ALA A 1 475 ? 94.314  100.202 99.236  1.00 54.45  ? 475 ALA A N    1 
ATOM 7002 C CA   . ALA A 1 475 ? 95.144  100.042 98.048  1.00 51.15  ? 475 ALA A CA   1 
ATOM 7003 C C    . ALA A 1 475 ? 96.484  100.746 98.215  1.00 47.11  ? 475 ALA A C    1 
ATOM 7004 O O    . ALA A 1 475 ? 97.530  100.209 97.828  1.00 50.68  ? 475 ALA A O    1 
ATOM 7005 C CB   . ALA A 1 475 ? 94.407  100.566 96.820  1.00 45.08  ? 475 ALA A CB   1 
ATOM 7006 H H    . ALA A 1 475 ? 93.583  100.639 99.108  1.00 55.01  ? 475 ALA A H    1 
ATOM 7007 H HA   . ALA A 1 475 ? 95.321  99.099  97.913  1.00 53.14  ? 475 ALA A HA   1 
ATOM 7008 H HB1  . ALA A 1 475 ? 94.183  101.500 96.956  1.00 48.91  ? 475 ALA A HB1  1 
ATOM 7009 H HB2  . ALA A 1 475 ? 94.977  100.473 96.041  1.00 47.17  ? 475 ALA A HB2  1 
ATOM 7010 H HB3  . ALA A 1 475 ? 93.598  100.042 96.705  1.00 48.50  ? 475 ALA A HB3  1 
ATOM 7011 N N    . ALA A 1 476 ? 96.477  101.948 98.796  1.00 47.56  ? 476 ALA A N    1 
ATOM 7012 C CA   . ALA A 1 476 ? 97.731  102.655 99.017  1.00 48.21  ? 476 ALA A CA   1 
ATOM 7013 C C    . ALA A 1 476 ? 98.630  101.910 99.990  1.00 52.11  ? 476 ALA A C    1 
ATOM 7014 O O    . ALA A 1 476 ? 99.849  101.864 99.789  1.00 53.69  ? 476 ALA A O    1 
ATOM 7015 C CB   . ALA A 1 476 ? 97.456  104.062 99.544  1.00 44.30  ? 476 ALA A CB   1 
ATOM 7016 H H    . ALA A 1 476 ? 95.777  102.369 99.066  1.00 51.40  ? 476 ALA A H    1 
ATOM 7017 H HA   . ALA A 1 476 ? 98.211  102.733 98.176  1.00 48.80  ? 476 ALA A HA   1 
ATOM 7018 H HB1  . ALA A 1 476 ? 97.137  104.609 98.808  1.00 49.09  ? 476 ALA A HB1  1 
ATOM 7019 H HB2  . ALA A 1 476 ? 96.790  104.018 100.247 1.00 48.71  ? 476 ALA A HB2  1 
ATOM 7020 H HB3  . ALA A 1 476 ? 98.280  104.432 99.895  1.00 46.90  ? 476 ALA A HB3  1 
ATOM 7021 N N    . ARG A 1 477 ? 98.059  101.301 101.031 1.00 54.87  ? 477 ARG A N    1 
ATOM 7022 C CA   . ARG A 1 477 ? 98.896  100.578 101.983 1.00 53.81  ? 477 ARG A CA   1 
ATOM 7023 C C    . ARG A 1 477 ? 99.445  99.299  101.360 1.00 51.74  ? 477 ARG A C    1 
ATOM 7024 O O    . ARG A 1 477 ? 100.597 98.926  101.603 1.00 53.01  ? 477 ARG A O    1 
ATOM 7025 C CB   . ARG A 1 477 ? 98.103  100.258 103.252 1.00 52.38  ? 477 ARG A CB   1 
ATOM 7026 C CG   . ARG A 1 477 ? 98.203  101.335 104.316 1.00 57.41  ? 477 ARG A CG   1 
ATOM 7027 C CD   . ARG A 1 477 ? 97.213  101.084 105.435 1.00 59.08  ? 477 ARG A CD   1 
ATOM 7028 N NE   . ARG A 1 477 ? 96.594  102.314 105.915 1.00 54.35  ? 477 ARG A NE   1 
ATOM 7029 C CZ   . ARG A 1 477 ? 95.285  102.512 106.021 1.00 57.27  ? 477 ARG A CZ   1 
ATOM 7030 N NH1  . ARG A 1 477 ? 94.409  101.563 105.719 1.00 58.95  ? 477 ARG A NH1  1 
ATOM 7031 N NH2  . ARG A 1 477 ? 94.839  103.689 106.451 1.00 58.65  ? 477 ARG A NH2  1 
ATOM 7032 H H    . ARG A 1 477 ? 97.217  101.289 101.208 1.00 53.70  ? 477 ARG A H    1 
ATOM 7033 H HA   . ARG A 1 477 ? 99.648  101.137 102.234 1.00 54.28  ? 477 ARG A HA   1 
ATOM 7034 H HB2  . ARG A 1 477 ? 97.169  100.163 103.014 1.00 53.32  ? 477 ARG A HB2  1 
ATOM 7035 H HB3  . ARG A 1 477 ? 98.430  99.429  103.630 1.00 52.37  ? 477 ARG A HB3  1 
ATOM 7036 H HG2  . ARG A 1 477 ? 99.096  101.325 104.693 1.00 54.80  ? 477 ARG A HG2  1 
ATOM 7037 H HG3  . ARG A 1 477 ? 98.010  102.199 103.922 1.00 57.20  ? 477 ARG A HG3  1 
ATOM 7038 H HD2  . ARG A 1 477 ? 96.529  100.488 105.101 1.00 56.00  ? 477 ARG A HD2  1 
ATOM 7039 H HD3  . ARG A 1 477 ? 97.671  100.665 106.182 1.00 54.76  ? 477 ARG A HD3  1 
ATOM 7040 H HE   . ARG A 1 477 ? 97.101  103.005 106.000 1.00 54.53  ? 477 ARG A HE   1 
ATOM 7041 H HH11 . ARG A 1 477 ? 94.672  100.796 105.441 1.00 55.95  ? 477 ARG A HH11 1 
ATOM 7042 H HH12 . ARG A 1 477 ? 93.568  101.716 105.800 1.00 58.39  ? 477 ARG A HH12 1 
ATOM 7043 H HH21 . ARG A 1 477 ? 95.396  104.312 106.650 1.00 59.24  ? 477 ARG A HH21 1 
ATOM 7044 H HH22 . ARG A 1 477 ? 93.991  103.827 106.527 1.00 60.73  ? 477 ARG A HH22 1 
ATOM 7045 N N    . GLY A 1 478 ? 98.628  98.606  100.565 1.00 48.55  ? 478 GLY A N    1 
ATOM 7046 C CA   . GLY A 1 478 ? 99.133  97.466  99.818  1.00 45.47  ? 478 GLY A CA   1 
ATOM 7047 C C    . GLY A 1 478 ? 100.275 97.841  98.893  1.00 47.07  ? 478 GLY A C    1 
ATOM 7048 O O    . GLY A 1 478 ? 101.279 97.128  98.806  1.00 46.23  ? 478 GLY A O    1 
ATOM 7049 H H    . GLY A 1 478 ? 97.793  98.774  100.449 1.00 50.03  ? 478 GLY A H    1 
ATOM 7050 H HA2  . GLY A 1 478 ? 99.445  96.789  100.438 1.00 46.79  ? 478 GLY A HA2  1 
ATOM 7051 H HA3  . GLY A 1 478 ? 98.415  97.085  99.287  1.00 46.79  ? 478 GLY A HA3  1 
ATOM 7052 N N    . GLY A 1 479 ? 100.140 98.966  98.191  1.00 47.95  ? 479 GLY A N    1 
ATOM 7053 C CA   . GLY A 1 479 ? 101.228 99.427  97.347  1.00 47.12  ? 479 GLY A CA   1 
ATOM 7054 C C    . GLY A 1 479 ? 102.473 99.756  98.144  1.00 50.55  ? 479 GLY A C    1 
ATOM 7055 O O    . GLY A 1 479 ? 103.592 99.470  97.713  1.00 54.91  ? 479 GLY A O    1 
ATOM 7056 H H    . GLY A 1 479 ? 99.443  99.470  98.188  1.00 49.04  ? 479 GLY A H    1 
ATOM 7057 H HA2  . GLY A 1 479 ? 101.452 98.735  96.707  1.00 48.25  ? 479 GLY A HA2  1 
ATOM 7058 H HA3  . GLY A 1 479 ? 100.949 100.222 96.863  1.00 48.12  ? 479 GLY A HA3  1 
ATOM 7059 N N    . ALA A 1 480 ? 102.295 100.352 99.324  1.00 49.10  ? 480 ALA A N    1 
ATOM 7060 C CA   . ALA A 1 480 ? 103.435 100.632 100.189 1.00 48.28  ? 480 ALA A CA   1 
ATOM 7061 C C    . ALA A 1 480 ? 104.144 99.341  100.576 1.00 45.59  ? 480 ALA A C    1 
ATOM 7062 O O    . ALA A 1 480 ? 105.377 99.262  100.548 1.00 45.69  ? 480 ALA A O    1 
ATOM 7063 C CB   . ALA A 1 480 ? 102.972 101.390 101.435 1.00 51.92  ? 480 ALA A CB   1 
ATOM 7064 H H    . ALA A 1 480 ? 101.536 100.594 99.642  1.00 49.91  ? 480 ALA A H    1 
ATOM 7065 H HA   . ALA A 1 480 ? 104.070 101.191 99.716  1.00 50.08  ? 480 ALA A HA   1 
ATOM 7066 H HB1  . ALA A 1 480 ? 102.336 100.842 101.920 1.00 51.93  ? 480 ALA A HB1  1 
ATOM 7067 H HB2  . ALA A 1 480 ? 103.740 101.580 101.996 1.00 54.57  ? 480 ALA A HB2  1 
ATOM 7068 H HB3  . ALA A 1 480 ? 102.549 102.219 101.159 1.00 52.56  ? 480 ALA A HB3  1 
ATOM 7069 N N    . ILE A 1 481 ? 103.375 98.312  100.933 1.00 46.03  ? 481 ILE A N    1 
ATOM 7070 C CA   . ILE A 1 481 ? 103.972 97.021  101.268 1.00 47.73  ? 481 ILE A CA   1 
ATOM 7071 C C    . ILE A 1 481 ? 104.744 96.469  100.079 1.00 49.09  ? 481 ILE A C    1 
ATOM 7072 O O    . ILE A 1 481 ? 105.868 95.974  100.225 1.00 49.88  ? 481 ILE A O    1 
ATOM 7073 C CB   . ILE A 1 481 ? 102.891 96.029  101.734 1.00 48.66  ? 481 ILE A CB   1 
ATOM 7074 C CG1  . ILE A 1 481 ? 102.341 96.437  103.099 1.00 46.08  ? 481 ILE A CG1  1 
ATOM 7075 C CG2  . ILE A 1 481 ? 103.464 94.619  101.788 1.00 43.24  ? 481 ILE A CG2  1 
ATOM 7076 C CD1  . ILE A 1 481 ? 101.068 95.718  103.484 1.00 46.07  ? 481 ILE A CD1  1 
ATOM 7077 H H    . ILE A 1 481 ? 102.518 98.332  100.984 1.00 48.57  ? 481 ILE A H    1 
ATOM 7078 H HA   . ILE A 1 481 ? 104.601 97.144  101.997 1.00 47.78  ? 481 ILE A HA   1 
ATOM 7079 H HB   . ILE A 1 481 ? 102.165 96.043  101.091 1.00 48.85  ? 481 ILE A HB   1 
ATOM 7080 H HG12 . ILE A 1 481 ? 103.009 96.243  103.774 1.00 46.25  ? 481 ILE A HG12 1 
ATOM 7081 H HG13 . ILE A 1 481 ? 102.151 97.388  103.088 1.00 47.90  ? 481 ILE A HG13 1 
ATOM 7082 H HG21 . ILE A 1 481 ? 102.894 94.061  102.338 1.00 45.21  ? 481 ILE A HG21 1 
ATOM 7083 H HG22 . ILE A 1 481 ? 103.505 94.256  100.889 1.00 44.75  ? 481 ILE A HG22 1 
ATOM 7084 H HG23 . ILE A 1 481 ? 104.354 94.657  102.171 1.00 45.86  ? 481 ILE A HG23 1 
ATOM 7085 H HD11 . ILE A 1 481 ? 100.795 96.030  104.358 1.00 46.43  ? 481 ILE A HD11 1 
ATOM 7086 H HD12 . ILE A 1 481 ? 100.379 95.917  102.830 1.00 46.36  ? 481 ILE A HD12 1 
ATOM 7087 H HD13 . ILE A 1 481 ? 101.231 94.763  103.514 1.00 45.77  ? 481 ILE A HD13 1 
ATOM 7088 N N    . LEU A 1 482 ? 104.149 96.528  98.885  1.00 49.62  ? 482 LEU A N    1 
ATOM 7089 C CA   . LEU A 1 482 ? 104.787 95.944  97.710  1.00 48.96  ? 482 LEU A CA   1 
ATOM 7090 C C    . LEU A 1 482 ? 105.977 96.764  97.223  1.00 51.43  ? 482 LEU A C    1 
ATOM 7091 O O    . LEU A 1 482 ? 106.791 96.250  96.448  1.00 54.02  ? 482 LEU A O    1 
ATOM 7092 C CB   . LEU A 1 482 ? 103.763 95.789  96.583  1.00 47.58  ? 482 LEU A CB   1 
ATOM 7093 C CG   . LEU A 1 482 ? 104.175 94.958  95.363  1.00 54.25  ? 482 LEU A CG   1 
ATOM 7094 C CD1  . LEU A 1 482 ? 104.807 93.638  95.774  1.00 53.89  ? 482 LEU A CD1  1 
ATOM 7095 C CD2  . LEU A 1 482 ? 102.976 94.710  94.461  1.00 58.71  ? 482 LEU A CD2  1 
ATOM 7096 H H    . LEU A 1 482 ? 103.385 96.894  98.729  1.00 49.05  ? 482 LEU A H    1 
ATOM 7097 H HA   . LEU A 1 482 ? 105.114 95.063  97.947  1.00 49.72  ? 482 LEU A HA   1 
ATOM 7098 H HB2  . LEU A 1 482 ? 102.967 95.375  96.953  1.00 48.65  ? 482 LEU A HB2  1 
ATOM 7099 H HB3  . LEU A 1 482 ? 103.539 96.675  96.259  1.00 49.64  ? 482 LEU A HB3  1 
ATOM 7100 H HG   . LEU A 1 482 ? 104.832 95.456  94.852  1.00 53.85  ? 482 LEU A HG   1 
ATOM 7101 H HD11 . LEU A 1 482 ? 104.877 93.066  94.993  1.00 54.18  ? 482 LEU A HD11 1 
ATOM 7102 H HD12 . LEU A 1 482 ? 105.690 93.809  96.137  1.00 53.16  ? 482 LEU A HD12 1 
ATOM 7103 H HD13 . LEU A 1 482 ? 104.248 93.216  96.444  1.00 53.28  ? 482 LEU A HD13 1 
ATOM 7104 H HD21 . LEU A 1 482 ? 102.616 95.562  94.170  1.00 58.50  ? 482 LEU A HD21 1 
ATOM 7105 H HD22 . LEU A 1 482 ? 103.263 94.193  93.692  1.00 57.53  ? 482 LEU A HD22 1 
ATOM 7106 H HD23 . LEU A 1 482 ? 102.304 94.218  94.958  1.00 54.55  ? 482 LEU A HD23 1 
ATOM 7107 N N    . GLY A 1 483 ? 106.096 98.016  97.656  1.00 53.86  ? 483 GLY A N    1 
ATOM 7108 C CA   . GLY A 1 483 ? 107.159 98.884  97.207  1.00 52.29  ? 483 GLY A CA   1 
ATOM 7109 C C    . GLY A 1 483 ? 108.552 98.344  97.460  1.00 52.93  ? 483 GLY A C    1 
ATOM 7110 O O    . GLY A 1 483 ? 109.331 98.118  96.528  1.00 52.99  ? 483 GLY A O    1 
ATOM 7111 H H    . GLY A 1 483 ? 105.561 98.384  98.220  1.00 52.06  ? 483 GLY A H    1 
ATOM 7112 H HA2  . GLY A 1 483 ? 107.066 99.035  96.255  1.00 52.04  ? 483 GLY A HA2  1 
ATOM 7113 H HA3  . GLY A 1 483 ? 107.080 99.740  97.659  1.00 51.57  ? 483 GLY A HA3  1 
ATOM 7114 N N    . PRO A 1 484 ? 108.898 98.129  98.731  1.00 56.88  ? 484 PRO A N    1 
ATOM 7115 C CA   . PRO A 1 484 ? 110.270 97.703  99.049  1.00 56.63  ? 484 PRO A CA   1 
ATOM 7116 C C    . PRO A 1 484 ? 110.701 96.430  98.342  1.00 55.92  ? 484 PRO A C    1 
ATOM 7117 O O    . PRO A 1 484 ? 111.886 96.286  98.019  1.00 61.30  ? 484 PRO A O    1 
ATOM 7118 C CB   . PRO A 1 484 ? 110.227 97.514  100.570 1.00 53.47  ? 484 PRO A CB   1 
ATOM 7119 C CG   . PRO A 1 484 ? 109.161 98.435  101.030 1.00 56.60  ? 484 PRO A CG   1 
ATOM 7120 C CD   . PRO A 1 484 ? 108.126 98.456  99.942  1.00 56.71  ? 484 PRO A CD   1 
ATOM 7121 H HA   . PRO A 1 484 ? 110.897 98.412  98.835  1.00 56.47  ? 484 PRO A HA   1 
ATOM 7122 H HB2  . PRO A 1 484 ? 110.003 96.595  100.781 1.00 55.38  ? 484 PRO A HB2  1 
ATOM 7123 H HB3  . PRO A 1 484 ? 111.083 97.757  100.957 1.00 54.68  ? 484 PRO A HB3  1 
ATOM 7124 H HG2  . PRO A 1 484 ? 108.778 98.101  101.856 1.00 55.71  ? 484 PRO A HG2  1 
ATOM 7125 H HG3  . PRO A 1 484 ? 109.532 99.322  101.163 1.00 55.70  ? 484 PRO A HG3  1 
ATOM 7126 H HD2  . PRO A 1 484 ? 107.447 97.784  100.105 1.00 53.69  ? 484 PRO A HD2  1 
ATOM 7127 H HD3  . PRO A 1 484 ? 107.740 99.343  99.868  1.00 54.28  ? 484 PRO A HD3  1 
ATOM 7128 N N    . LEU A 1 485 ? 109.778 95.500  98.085  1.00 51.52  ? 485 LEU A N    1 
ATOM 7129 C CA   . LEU A 1 485 ? 110.155 94.230  97.474  1.00 52.84  ? 485 LEU A CA   1 
ATOM 7130 C C    . LEU A 1 485 ? 110.758 94.407  96.087  1.00 55.48  ? 485 LEU A C    1 
ATOM 7131 O O    . LEU A 1 485 ? 111.474 93.516  95.618  1.00 59.14  ? 485 LEU A O    1 
ATOM 7132 C CB   . LEU A 1 485 ? 108.937 93.308  97.386  1.00 52.71  ? 485 LEU A CB   1 
ATOM 7133 C CG   . LEU A 1 485 ? 108.413 92.703  98.690  1.00 58.26  ? 485 LEU A CG   1 
ATOM 7134 C CD1  . LEU A 1 485 ? 107.321 91.687  98.397  1.00 59.61  ? 485 LEU A CD1  1 
ATOM 7135 C CD2  . LEU A 1 485 ? 109.530 92.058  99.490  1.00 61.95  ? 485 LEU A CD2  1 
ATOM 7136 H H    . LEU A 1 485 ? 108.938 95.581  98.253  1.00 53.67  ? 485 LEU A H    1 
ATOM 7137 H HA   . LEU A 1 485 ? 110.825 93.803  98.029  1.00 53.80  ? 485 LEU A HA   1 
ATOM 7138 H HB2  . LEU A 1 485 ? 108.207 93.812  96.993  1.00 53.93  ? 485 LEU A HB2  1 
ATOM 7139 H HB3  . LEU A 1 485 ? 109.164 92.568  96.801  1.00 53.48  ? 485 LEU A HB3  1 
ATOM 7140 H HG   . LEU A 1 485 ? 108.027 93.409  99.232  1.00 55.80  ? 485 LEU A HG   1 
ATOM 7141 H HD11 . LEU A 1 485 ? 107.689 90.977  97.848  1.00 59.54  ? 485 LEU A HD11 1 
ATOM 7142 H HD12 . LEU A 1 485 ? 106.995 91.323  99.234  1.00 57.37  ? 485 LEU A HD12 1 
ATOM 7143 H HD13 . LEU A 1 485 ? 106.598 92.129  97.924  1.00 56.99  ? 485 LEU A HD13 1 
ATOM 7144 H HD21 . LEU A 1 485 ? 109.141 91.509  100.189 1.00 60.01  ? 485 LEU A HD21 1 
ATOM 7145 H HD22 . LEU A 1 485 ? 110.065 91.507  98.897  1.00 60.23  ? 485 LEU A HD22 1 
ATOM 7146 H HD23 . LEU A 1 485 ? 110.081 92.753  99.883  1.00 58.46  ? 485 LEU A HD23 1 
ATOM 7147 N N    . VAL A 1 486 ? 110.490 95.531  95.419  1.00 52.79  ? 486 VAL A N    1 
ATOM 7148 C CA   . VAL A 1 486 ? 110.989 95.725  94.061  1.00 56.07  ? 486 VAL A CA   1 
ATOM 7149 C C    . VAL A 1 486 ? 112.510 95.775  94.039  1.00 62.40  ? 486 VAL A C    1 
ATOM 7150 O O    . VAL A 1 486 ? 113.135 95.455  93.021  1.00 66.80  ? 486 VAL A O    1 
ATOM 7151 C CB   . VAL A 1 486 ? 110.377 97.000  93.450  1.00 50.62  ? 486 VAL A CB   1 
ATOM 7152 C CG1  . VAL A 1 486 ? 111.138 97.419  92.199  1.00 54.81  ? 486 VAL A CG1  1 
ATOM 7153 C CG2  . VAL A 1 486 ? 108.910 96.781  93.140  1.00 56.73  ? 486 VAL A CG2  1 
ATOM 7154 H H    . VAL A 1 486 ? 110.028 96.188  95.727  1.00 54.12  ? 486 VAL A H    1 
ATOM 7155 H HA   . VAL A 1 486 ? 110.712 94.971  93.516  1.00 57.48  ? 486 VAL A HA   1 
ATOM 7156 H HB   . VAL A 1 486 ? 110.442 97.721  94.095  1.00 52.54  ? 486 VAL A HB   1 
ATOM 7157 H HG11 . VAL A 1 486 ? 110.596 98.047  91.697  1.00 56.20  ? 486 VAL A HG11 1 
ATOM 7158 H HG12 . VAL A 1 486 ? 111.971 97.841  92.459  1.00 54.92  ? 486 VAL A HG12 1 
ATOM 7159 H HG13 . VAL A 1 486 ? 111.316 96.633  91.659  1.00 55.89  ? 486 VAL A HG13 1 
ATOM 7160 H HG21 . VAL A 1 486 ? 108.641 95.912  93.479  1.00 56.67  ? 486 VAL A HG21 1 
ATOM 7161 H HG22 . VAL A 1 486 ? 108.396 97.477  93.574  1.00 54.64  ? 486 VAL A HG22 1 
ATOM 7162 H HG23 . VAL A 1 486 ? 108.777 96.818  92.180  1.00 57.06  ? 486 VAL A HG23 1 
ATOM 7163 N N    . ARG A 1 487 ? 113.132 96.171  95.149  1.00 57.82  ? 487 ARG A N    1 
ATOM 7164 C CA   . ARG A 1 487 ? 114.579 96.342  95.172  1.00 54.38  ? 487 ARG A CA   1 
ATOM 7165 C C    . ARG A 1 487 ? 115.334 95.036  94.978  1.00 56.23  ? 487 ARG A C    1 
ATOM 7166 O O    . ARG A 1 487 ? 116.542 95.075  94.725  1.00 59.59  ? 487 ARG A O    1 
ATOM 7167 C CB   . ARG A 1 487 ? 115.005 96.988  96.487  1.00 52.11  ? 487 ARG A CB   1 
ATOM 7168 C CG   . ARG A 1 487 ? 114.674 98.460  96.559  1.00 53.45  ? 487 ARG A CG   1 
ATOM 7169 C CD   . ARG A 1 487 ? 115.250 99.101  97.799  1.00 59.41  ? 487 ARG A CD   1 
ATOM 7170 N NE   . ARG A 1 487 ? 114.403 100.195 98.258  1.00 61.96  ? 487 ARG A NE   1 
ATOM 7171 C CZ   . ARG A 1 487 ? 113.517 100.102 99.242  1.00 63.84  ? 487 ARG A CZ   1 
ATOM 7172 N NH1  . ARG A 1 487 ? 113.340 98.977  99.915  1.00 62.18  ? 487 ARG A NH1  1 
ATOM 7173 N NH2  . ARG A 1 487 ? 112.785 101.166 99.554  1.00 64.99  ? 487 ARG A NH2  1 
ATOM 7174 H H    . ARG A 1 487 ? 112.742 96.345  95.896  1.00 57.11  ? 487 ARG A H    1 
ATOM 7175 H HA   . ARG A 1 487 ? 114.833 96.940  94.452  1.00 56.35  ? 487 ARG A HA   1 
ATOM 7176 H HB2  . ARG A 1 487 ? 114.549 96.543  97.218  1.00 55.55  ? 487 ARG A HB2  1 
ATOM 7177 H HB3  . ARG A 1 487 ? 115.965 96.892  96.588  1.00 55.62  ? 487 ARG A HB3  1 
ATOM 7178 H HG2  . ARG A 1 487 ? 115.047 98.909  95.784  1.00 55.79  ? 487 ARG A HG2  1 
ATOM 7179 H HG3  . ARG A 1 487 ? 113.711 98.570  96.579  1.00 56.42  ? 487 ARG A HG3  1 
ATOM 7180 H HD2  . ARG A 1 487 ? 115.331 98.438  98.500  1.00 59.37  ? 487 ARG A HD2  1 
ATOM 7181 H HD3  . ARG A 1 487 ? 116.123 99.467  97.588  1.00 61.13  ? 487 ARG A HD3  1 
ATOM 7182 H HE   . ARG A 1 487 ? 114.463 100.946 97.844  1.00 62.79  ? 487 ARG A HE   1 
ATOM 7183 H HH11 . ARG A 1 487 ? 113.803 98.278  99.727  1.00 61.12  ? 487 ARG A HH11 1 
ATOM 7184 H HH12 . ARG A 1 487 ? 112.759 98.945  100.547 1.00 61.81  ? 487 ARG A HH12 1 
ATOM 7185 H HH21 . ARG A 1 487 ? 112.889 101.903 99.124  1.00 63.34  ? 487 ARG A HH21 1 
ATOM 7186 H HH22 . ARG A 1 487 ? 112.208 101.114 100.189 1.00 63.16  ? 487 ARG A HH22 1 
ATOM 7187 N N    . LEU A 1 488 ? 114.662 93.889  95.085  1.00 57.90  ? 488 LEU A N    1 
ATOM 7188 C CA   . LEU A 1 488 ? 115.337 92.617  94.861  1.00 60.26  ? 488 LEU A CA   1 
ATOM 7189 C C    . LEU A 1 488 ? 115.845 92.490  93.432  1.00 64.75  ? 488 LEU A C    1 
ATOM 7190 O O    . LEU A 1 488 ? 116.683 91.624  93.159  1.00 74.98  ? 488 LEU A O    1 
ATOM 7191 C CB   . LEU A 1 488 ? 114.394 91.458  95.188  1.00 62.39  ? 488 LEU A CB   1 
ATOM 7192 C CG   . LEU A 1 488 ? 113.871 91.365  96.625  1.00 65.71  ? 488 LEU A CG   1 
ATOM 7193 C CD1  . LEU A 1 488 ? 113.564 89.918  96.980  1.00 66.23  ? 488 LEU A CD1  1 
ATOM 7194 C CD2  . LEU A 1 488 ? 114.847 91.963  97.630  1.00 61.73  ? 488 LEU A CD2  1 
ATOM 7195 H H    . LEU A 1 488 ? 113.828 93.821  95.284  1.00 59.32  ? 488 LEU A H    1 
ATOM 7196 H HA   . LEU A 1 488 ? 116.109 92.561  95.446  1.00 61.56  ? 488 LEU A HA   1 
ATOM 7197 H HB2  . LEU A 1 488 ? 113.621 91.525  94.606  1.00 62.01  ? 488 LEU A HB2  1 
ATOM 7198 H HB3  . LEU A 1 488 ? 114.862 90.629  95.001  1.00 63.08  ? 488 LEU A HB3  1 
ATOM 7199 H HG   . LEU A 1 488 ? 113.042 91.865  96.687  1.00 62.68  ? 488 LEU A HG   1 
ATOM 7200 H HD11 . LEU A 1 488 ? 113.216 89.882  97.885  1.00 63.64  ? 488 LEU A HD11 1 
ATOM 7201 H HD12 . LEU A 1 488 ? 112.905 89.574  96.358  1.00 65.85  ? 488 LEU A HD12 1 
ATOM 7202 H HD13 . LEU A 1 488 ? 114.381 89.399  96.919  1.00 65.65  ? 488 LEU A HD13 1 
ATOM 7203 H HD21 . LEU A 1 488 ? 114.548 91.743  98.526  1.00 61.89  ? 488 LEU A HD21 1 
ATOM 7204 H HD22 . LEU A 1 488 ? 115.728 91.589  97.475  1.00 62.51  ? 488 LEU A HD22 1 
ATOM 7205 H HD23 . LEU A 1 488 ? 114.871 92.926  97.517  1.00 60.57  ? 488 LEU A HD23 1 
ATOM 7206 N N    . LEU A 1 489 ? 115.361 93.331  92.520  1.00 59.37  ? 489 LEU A N    1 
ATOM 7207 C CA   . LEU A 1 489 ? 115.856 93.359  91.150  1.00 63.76  ? 489 LEU A CA   1 
ATOM 7208 C C    . LEU A 1 489 ? 117.131 94.178  91.003  1.00 70.04  ? 489 LEU A C    1 
ATOM 7209 O O    . LEU A 1 489 ? 117.664 94.269  89.892  1.00 69.81  ? 489 LEU A O    1 
ATOM 7210 C CB   . LEU A 1 489 ? 114.782 93.919  90.213  1.00 60.94  ? 489 LEU A CB   1 
ATOM 7211 C CG   . LEU A 1 489 ? 113.354 93.420  90.437  1.00 63.19  ? 489 LEU A CG   1 
ATOM 7212 C CD1  . LEU A 1 489 ? 112.410 94.060  89.435  1.00 64.41  ? 489 LEU A CD1  1 
ATOM 7213 C CD2  . LEU A 1 489 ? 113.292 91.904  90.339  1.00 68.05  ? 489 LEU A CD2  1 
ATOM 7214 H H    . LEU A 1 489 ? 114.737 93.902  92.673  1.00 60.68  ? 489 LEU A H    1 
ATOM 7215 H HA   . LEU A 1 489 ? 116.051 92.451  90.870  1.00 64.65  ? 489 LEU A HA   1 
ATOM 7216 H HB2  . LEU A 1 489 ? 114.768 94.884  90.310  1.00 62.80  ? 489 LEU A HB2  1 
ATOM 7217 H HB3  . LEU A 1 489 ? 115.026 93.691  89.302  1.00 63.63  ? 489 LEU A HB3  1 
ATOM 7218 H HG   . LEU A 1 489 ? 113.064 93.675  91.326  1.00 62.22  ? 489 LEU A HG   1 
ATOM 7219 H HD11 . LEU A 1 489 ? 111.509 93.738  89.598  1.00 64.12  ? 489 LEU A HD11 1 
ATOM 7220 H HD12 . LEU A 1 489 ? 112.441 95.024  89.544  1.00 63.22  ? 489 LEU A HD12 1 
ATOM 7221 H HD13 . LEU A 1 489 ? 112.691 93.819  88.539  1.00 64.13  ? 489 LEU A HD13 1 
ATOM 7222 H HD21 . LEU A 1 489 ? 112.367 91.621  90.411  1.00 68.09  ? 489 LEU A HD21 1 
ATOM 7223 H HD22 . LEU A 1 489 ? 113.657 91.628  89.484  1.00 68.01  ? 489 LEU A HD22 1 
ATOM 7224 H HD23 . LEU A 1 489 ? 113.813 91.519  91.061  1.00 64.66  ? 489 LEU A HD23 1 
ATOM 7225 N N    . GLY A 1 490 ? 117.631 94.772  92.086  1.00 69.82  ? 490 GLY A N    1 
ATOM 7226 C CA   . GLY A 1 490 ? 118.828 95.592  92.011  1.00 68.94  ? 490 GLY A CA   1 
ATOM 7227 C C    . GLY A 1 490 ? 120.094 94.832  91.674  1.00 72.77  ? 490 GLY A C    1 
ATOM 7228 O O    . GLY A 1 490 ? 121.116 95.468  91.393  1.00 85.52  ? 490 GLY A O    1 
ATOM 7229 H H    . GLY A 1 490 ? 117.291 94.716  92.874  1.00 66.15  ? 490 GLY A H    1 
ATOM 7230 H HA2  . GLY A 1 490 ? 118.701 96.275  91.334  1.00 69.22  ? 490 GLY A HA2  1 
ATOM 7231 H HA3  . GLY A 1 490 ? 118.962 96.035  92.863  1.00 68.27  ? 490 GLY A HA3  1 
ATOM 7232 N N    . VAL A 1 491 ? 120.057 93.499  91.701  1.00 73.08  ? 491 VAL A N    1 
ATOM 7233 C CA   . VAL A 1 491 ? 121.244 92.724  91.346  1.00 75.34  ? 491 VAL A CA   1 
ATOM 7234 C C    . VAL A 1 491 ? 121.587 92.915  89.873  1.00 81.76  ? 491 VAL A C    1 
ATOM 7235 O O    . VAL A 1 491 ? 122.766 92.937  89.497  1.00 87.00  ? 491 VAL A O    1 
ATOM 7236 C CB   . VAL A 1 491 ? 121.060 91.239  91.720  1.00 80.82  ? 491 VAL A CB   1 
ATOM 7237 C CG1  . VAL A 1 491 ? 120.432 91.115  93.108  1.00 81.20  ? 491 VAL A CG1  1 
ATOM 7238 C CG2  . VAL A 1 491 ? 120.219 90.505  90.693  1.00 82.57  ? 491 VAL A CG2  1 
ATOM 7239 H H    . VAL A 1 491 ? 119.370 93.032  91.916  1.00 73.76  ? 491 VAL A H    1 
ATOM 7240 H HA   . VAL A 1 491 ? 121.994 93.062  91.859  1.00 76.10  ? 491 VAL A HA   1 
ATOM 7241 H HB   . VAL A 1 491 ? 121.932 90.816  91.744  1.00 80.77  ? 491 VAL A HB   1 
ATOM 7242 H HG11 . VAL A 1 491 ? 120.479 90.189  93.393  1.00 80.74  ? 491 VAL A HG11 1 
ATOM 7243 H HG12 . VAL A 1 491 ? 120.931 91.676  93.723  1.00 79.98  ? 491 VAL A HG12 1 
ATOM 7244 H HG13 . VAL A 1 491 ? 119.506 91.403  93.079  1.00 77.51  ? 491 VAL A HG13 1 
ATOM 7245 H HG21 . VAL A 1 491 ? 120.054 89.603  91.010  1.00 81.30  ? 491 VAL A HG21 1 
ATOM 7246 H HG22 . VAL A 1 491 ? 119.377 90.974  90.591  1.00 79.32  ? 491 VAL A HG22 1 
ATOM 7247 H HG23 . VAL A 1 491 ? 120.695 90.468  89.849  1.00 80.09  ? 491 VAL A HG23 1 
ATOM 7248 N N    . HIS A 1 492 ? 120.575 93.055  89.011  1.00 82.54  ? 492 HIS A N    1 
ATOM 7249 C CA   . HIS A 1 492 ? 120.864 93.441  87.631  1.00 88.87  ? 492 HIS A CA   1 
ATOM 7250 C C    . HIS A 1 492 ? 121.518 94.816  87.579  1.00 84.06  ? 492 HIS A C    1 
ATOM 7251 O O    . HIS A 1 492 ? 122.486 95.024  86.839  1.00 87.97  ? 492 HIS A O    1 
ATOM 7252 C CB   . HIS A 1 492 ? 119.600 93.437  86.759  1.00 86.61  ? 492 HIS A CB   1 
ATOM 7253 C CG   . HIS A 1 492 ? 118.767 92.193  86.859  1.00 92.35  ? 492 HIS A CG   1 
ATOM 7254 N ND1  . HIS A 1 492 ? 117.865 91.839  85.879  1.00 97.48  ? 492 HIS A ND1  1 
ATOM 7255 C CD2  . HIS A 1 492 ? 118.705 91.215  87.794  1.00 90.92  ? 492 HIS A CD2  1 
ATOM 7256 C CE1  . HIS A 1 492 ? 117.276 90.705  86.212  1.00 98.99  ? 492 HIS A CE1  1 
ATOM 7257 N NE2  . HIS A 1 492 ? 117.767 90.305  87.370  1.00 94.68  ? 492 HIS A NE2  1 
ATOM 7258 H H    . HIS A 1 492 ? 119.744 92.954  89.204  1.00 80.81  ? 492 HIS A H    1 
ATOM 7259 H HA   . HIS A 1 492 ? 121.485 92.801  87.249  1.00 88.64  ? 492 HIS A HA   1 
ATOM 7260 H HB2  . HIS A 1 492 ? 119.042 94.186  87.020  1.00 84.47  ? 492 HIS A HB2  1 
ATOM 7261 H HB3  . HIS A 1 492 ? 119.859 93.544  85.829  1.00 87.98  ? 492 HIS A HB3  1 
ATOM 7262 H HD2  . HIS A 1 492 ? 119.196 91.172  88.574  1.00 89.67  ? 492 HIS A HD2  1 
ATOM 7263 H HE1  . HIS A 1 492 ? 116.628 90.263  85.715  1.00 97.66  ? 492 HIS A HE1  1 
ATOM 7264 H HE2  . HIS A 1 492 ? 117.536 89.589  87.787  1.00 95.28  ? 492 HIS A HE2  1 
ATOM 7265 N N    . GLY A 1 493 ? 121.009 95.762  88.363  1.00 75.04  ? 493 GLY A N    1 
ATOM 7266 C CA   . GLY A 1 493 ? 121.549 97.100  88.393  1.00 71.56  ? 493 GLY A CA   1 
ATOM 7267 C C    . GLY A 1 493 ? 120.666 98.043  89.185  1.00 73.83  ? 493 GLY A C    1 
ATOM 7268 O O    . GLY A 1 493 ? 119.447 97.864  89.264  1.00 81.42  ? 493 GLY A O    1 
ATOM 7269 H H    . GLY A 1 493 ? 120.344 95.646  88.896  1.00 77.91  ? 493 GLY A H    1 
ATOM 7270 H HA2  . GLY A 1 493 ? 122.432 97.076  88.791  1.00 75.72  ? 493 GLY A HA2  1 
ATOM 7271 H HA3  . GLY A 1 493 ? 121.627 97.438  87.487  1.00 74.59  ? 493 GLY A HA3  1 
ATOM 7272 N N    . PRO A 1 494 ? 121.265 99.075  89.790  1.00 72.72  ? 494 PRO A N    1 
ATOM 7273 C CA   . PRO A 1 494 ? 120.467 100.020 90.587  1.00 75.12  ? 494 PRO A CA   1 
ATOM 7274 C C    . PRO A 1 494 ? 119.502 100.854 89.762  1.00 70.84  ? 494 PRO A C    1 
ATOM 7275 O O    . PRO A 1 494 ? 118.606 101.483 90.341  1.00 68.95  ? 494 PRO A O    1 
ATOM 7276 C CB   . PRO A 1 494 ? 121.531 100.902 91.251  1.00 79.73  ? 494 PRO A CB   1 
ATOM 7277 C CG   . PRO A 1 494 ? 122.693 100.845 90.330  1.00 79.89  ? 494 PRO A CG   1 
ATOM 7278 C CD   . PRO A 1 494 ? 122.684 99.468  89.727  1.00 73.97  ? 494 PRO A CD   1 
ATOM 7279 H HA   . PRO A 1 494 ? 119.976 99.546  91.276  1.00 73.94  ? 494 PRO A HA   1 
ATOM 7280 H HB2  . PRO A 1 494 ? 121.201 101.810 91.335  1.00 78.18  ? 494 PRO A HB2  1 
ATOM 7281 H HB3  . PRO A 1 494 ? 121.764 100.539 92.120  1.00 78.36  ? 494 PRO A HB3  1 
ATOM 7282 H HG2  . PRO A 1 494 ? 122.593 101.520 89.640  1.00 78.05  ? 494 PRO A HG2  1 
ATOM 7283 H HG3  . PRO A 1 494 ? 123.511 100.991 90.831  1.00 79.14  ? 494 PRO A HG3  1 
ATOM 7284 H HD2  . PRO A 1 494 ? 122.985 99.503  88.806  1.00 73.92  ? 494 PRO A HD2  1 
ATOM 7285 H HD3  . PRO A 1 494 ? 123.227 98.865  90.259  1.00 74.29  ? 494 PRO A HD3  1 
ATOM 7286 N N    . TRP A 1 495 ? 119.658 100.886 88.438  1.00 63.21  ? 495 TRP A N    1 
ATOM 7287 C CA   . TRP A 1 495 ? 118.827 101.745 87.601  1.00 61.54  ? 495 TRP A CA   1 
ATOM 7288 C C    . TRP A 1 495 ? 117.422 101.191 87.392  1.00 65.37  ? 495 TRP A C    1 
ATOM 7289 O O    . TRP A 1 495 ? 116.486 101.971 87.186  1.00 64.63  ? 495 TRP A O    1 
ATOM 7290 C CB   . TRP A 1 495 ? 119.501 101.973 86.245  1.00 62.16  ? 495 TRP A CB   1 
ATOM 7291 C CG   . TRP A 1 495 ? 119.920 100.714 85.535  1.00 68.70  ? 495 TRP A CG   1 
ATOM 7292 C CD1  . TRP A 1 495 ? 121.093 100.035 85.696  1.00 76.74  ? 495 TRP A CD1  1 
ATOM 7293 C CD2  . TRP A 1 495 ? 119.166 99.984  84.560  1.00 67.01  ? 495 TRP A CD2  1 
ATOM 7294 N NE1  . TRP A 1 495 ? 121.118 98.932  84.880  1.00 77.67  ? 495 TRP A NE1  1 
ATOM 7295 C CE2  . TRP A 1 495 ? 119.946 98.877  84.172  1.00 78.44  ? 495 TRP A CE2  1 
ATOM 7296 C CE3  . TRP A 1 495 ? 117.909 100.160 83.977  1.00 66.53  ? 495 TRP A CE3  1 
ATOM 7297 C CZ2  . TRP A 1 495 ? 119.510 97.950  83.229  1.00 83.47  ? 495 TRP A CZ2  1 
ATOM 7298 C CZ3  . TRP A 1 495 ? 117.478 99.238  83.039  1.00 78.99  ? 495 TRP A CZ3  1 
ATOM 7299 C CH2  . TRP A 1 495 ? 118.276 98.147  82.675  1.00 81.67  ? 495 TRP A CH2  1 
ATOM 7300 H H    . TRP A 1 495 ? 120.238 100.421 88.011  1.00 68.37  ? 495 TRP A H    1 
ATOM 7301 H HA   . TRP A 1 495 ? 118.740 102.608 88.035  1.00 64.36  ? 495 TRP A HA   1 
ATOM 7302 H HB2  . TRP A 1 495 ? 118.883 102.445 85.666  1.00 63.86  ? 495 TRP A HB2  1 
ATOM 7303 H HB3  . TRP A 1 495 ? 120.297 102.511 86.381  1.00 65.06  ? 495 TRP A HB3  1 
ATOM 7304 H HD1  . TRP A 1 495 ? 121.778 100.285 86.273  1.00 74.53  ? 495 TRP A HD1  1 
ATOM 7305 H HE1  . TRP A 1 495 ? 121.763 98.366  84.824  1.00 75.81  ? 495 TRP A HE1  1 
ATOM 7306 H HE3  . TRP A 1 495 ? 117.375 100.882 84.214  1.00 68.02  ? 495 TRP A HE3  1 
ATOM 7307 H HZ2  . TRP A 1 495 ? 120.038 97.224  82.984  1.00 80.73  ? 495 TRP A HZ2  1 
ATOM 7308 H HZ3  . TRP A 1 495 ? 116.643 99.346  82.644  1.00 79.28  ? 495 TRP A HZ3  1 
ATOM 7309 H HH2  . TRP A 1 495 ? 117.960 97.544  82.041  1.00 79.96  ? 495 TRP A HH2  1 
ATOM 7310 N N    . LEU A 1 496 ? 117.250 99.864  87.414  1.00 66.43  ? 496 LEU A N    1 
ATOM 7311 C CA   . LEU A 1 496 ? 115.934 99.297  87.119  1.00 63.35  ? 496 LEU A CA   1 
ATOM 7312 C C    . LEU A 1 496 ? 114.892 99.676  88.164  1.00 61.04  ? 496 LEU A C    1 
ATOM 7313 O O    . LEU A 1 496 ? 113.764 100.039 87.779  1.00 62.31  ? 496 LEU A O    1 
ATOM 7314 C CB   . LEU A 1 496 ? 116.051 97.778  86.960  1.00 53.83  ? 496 LEU A CB   1 
ATOM 7315 C CG   . LEU A 1 496 ? 114.855 97.054  86.338  1.00 54.87  ? 496 LEU A CG   1 
ATOM 7316 C CD1  . LEU A 1 496 ? 114.495 97.648  84.986  1.00 62.26  ? 496 LEU A CD1  1 
ATOM 7317 C CD2  . LEU A 1 496 ? 115.149 95.568  86.207  1.00 67.32  ? 496 LEU A CD2  1 
ATOM 7318 H H    . LEU A 1 496 ? 117.863 99.287  87.593  1.00 67.48  ? 496 LEU A H    1 
ATOM 7319 H HA   . LEU A 1 496 ? 115.637 99.661  86.271  1.00 65.57  ? 496 LEU A HA   1 
ATOM 7320 H HB2  . LEU A 1 496 ? 116.818 97.593  86.396  1.00 61.17  ? 496 LEU A HB2  1 
ATOM 7321 H HB3  . LEU A 1 496 ? 116.195 97.382  87.831  1.00 58.12  ? 496 LEU A HB3  1 
ATOM 7322 H HG   . LEU A 1 496 ? 114.087 97.156  86.923  1.00 57.34  ? 496 LEU A HG   1 
ATOM 7323 H HD11 . LEU A 1 496 ? 115.306 97.764  84.467  1.00 63.70  ? 496 LEU A HD11 1 
ATOM 7324 H HD12 . LEU A 1 496 ? 113.891 97.044  84.526  1.00 64.78  ? 496 LEU A HD12 1 
ATOM 7325 H HD13 . LEU A 1 496 ? 114.064 98.507  85.122  1.00 63.13  ? 496 LEU A HD13 1 
ATOM 7326 H HD21 . LEU A 1 496 ? 114.371 95.124  85.835  1.00 65.59  ? 496 LEU A HD21 1 
ATOM 7327 H HD22 . LEU A 1 496 ? 115.912 95.448  85.620  1.00 67.69  ? 496 LEU A HD22 1 
ATOM 7328 H HD23 . LEU A 1 496 ? 115.347 95.207  87.085  1.00 66.37  ? 496 LEU A HD23 1 
ATOM 7329 N N    . PRO A 1 497 ? 115.159 99.575  89.471  1.00 54.13  ? 497 PRO A N    1 
ATOM 7330 C CA   . PRO A 1 497 ? 114.140 100.003 90.444  1.00 53.54  ? 497 PRO A CA   1 
ATOM 7331 C C    . PRO A 1 497 ? 113.726 101.451 90.267  1.00 57.98  ? 497 PRO A C    1 
ATOM 7332 O O    . PRO A 1 497 ? 112.535 101.773 90.359  1.00 60.84  ? 497 PRO A O    1 
ATOM 7333 C CB   . PRO A 1 497 ? 114.826 99.770  91.797  1.00 57.79  ? 497 PRO A CB   1 
ATOM 7334 C CG   . PRO A 1 497 ? 115.879 98.765  91.533  1.00 59.85  ? 497 PRO A CG   1 
ATOM 7335 C CD   . PRO A 1 497 ? 116.344 99.000  90.132  1.00 59.79  ? 497 PRO A CD   1 
ATOM 7336 H HA   . PRO A 1 497 ? 113.356 99.435  90.381  1.00 55.87  ? 497 PRO A HA   1 
ATOM 7337 H HB2  . PRO A 1 497 ? 115.216 100.600 92.113  1.00 58.81  ? 497 PRO A HB2  1 
ATOM 7338 H HB3  . PRO A 1 497 ? 114.180 99.430  92.436  1.00 58.29  ? 497 PRO A HB3  1 
ATOM 7339 H HG2  . PRO A 1 497 ? 116.609 98.890  92.158  1.00 61.68  ? 497 PRO A HG2  1 
ATOM 7340 H HG3  . PRO A 1 497 ? 115.504 97.875  91.621  1.00 59.90  ? 497 PRO A HG3  1 
ATOM 7341 H HD2  . PRO A 1 497 ? 117.079 99.631  90.119  1.00 63.14  ? 497 PRO A HD2  1 
ATOM 7342 H HD3  . PRO A 1 497 ? 116.593 98.157  89.726  1.00 61.98  ? 497 PRO A HD3  1 
ATOM 7343 N N    . LEU A 1 498 ? 114.686 102.338 89.999  1.00 56.38  ? 498 LEU A N    1 
ATOM 7344 C CA   . LEU A 1 498 ? 114.353 103.742 89.790  1.00 57.44  ? 498 LEU A CA   1 
ATOM 7345 C C    . LEU A 1 498 ? 113.547 103.927 88.512  1.00 54.61  ? 498 LEU A C    1 
ATOM 7346 O O    . LEU A 1 498 ? 112.631 104.755 88.465  1.00 58.99  ? 498 LEU A O    1 
ATOM 7347 C CB   . LEU A 1 498 ? 115.632 104.579 89.751  1.00 59.43  ? 498 LEU A CB   1 
ATOM 7348 C CG   . LEU A 1 498 ? 116.443 104.652 91.050  1.00 61.70  ? 498 LEU A CG   1 
ATOM 7349 C CD1  . LEU A 1 498 ? 117.517 105.723 90.950  1.00 63.51  ? 498 LEU A CD1  1 
ATOM 7350 C CD2  . LEU A 1 498 ? 115.551 104.909 92.256  1.00 57.98  ? 498 LEU A CD2  1 
ATOM 7351 H H    . LEU A 1 498 ? 115.523 102.154 89.935  1.00 58.16  ? 498 LEU A H    1 
ATOM 7352 H HA   . LEU A 1 498 ? 113.805 104.050 90.527  1.00 58.45  ? 498 LEU A HA   1 
ATOM 7353 H HB2  . LEU A 1 498 ? 116.215 104.211 89.069  1.00 59.07  ? 498 LEU A HB2  1 
ATOM 7354 H HB3  . LEU A 1 498 ? 115.391 105.487 89.512  1.00 58.66  ? 498 LEU A HB3  1 
ATOM 7355 H HG   . LEU A 1 498 ? 116.887 103.800 91.187  1.00 61.66  ? 498 LEU A HG   1 
ATOM 7356 H HD11 . LEU A 1 498 ? 117.982 105.784 91.799  1.00 62.23  ? 498 LEU A HD11 1 
ATOM 7357 H HD12 . LEU A 1 498 ? 118.141 105.477 90.249  1.00 61.83  ? 498 LEU A HD12 1 
ATOM 7358 H HD13 . LEU A 1 498 ? 117.098 106.572 90.739  1.00 60.29  ? 498 LEU A HD13 1 
ATOM 7359 H HD21 . LEU A 1 498 ? 115.045 104.106 92.452  1.00 60.69  ? 498 LEU A HD21 1 
ATOM 7360 H HD22 . LEU A 1 498 ? 116.109 105.141 93.015  1.00 60.52  ? 498 LEU A HD22 1 
ATOM 7361 H HD23 . LEU A 1 498 ? 114.949 105.642 92.053  1.00 56.90  ? 498 LEU A HD23 1 
ATOM 7362 N N    . LEU A 1 499 ? 113.864 103.160 87.466  1.00 48.81  ? 499 LEU A N    1 
ATOM 7363 C CA   . LEU A 1 499 ? 113.075 103.237 86.242  1.00 45.81  ? 499 LEU A CA   1 
ATOM 7364 C C    . LEU A 1 499 ? 111.630 102.837 86.502  1.00 47.78  ? 499 LEU A C    1 
ATOM 7365 O O    . LEU A 1 499 ? 110.701 103.474 85.997  1.00 46.93  ? 499 LEU A O    1 
ATOM 7366 C CB   . LEU A 1 499 ? 113.685 102.347 85.158  1.00 48.16  ? 499 LEU A CB   1 
ATOM 7367 C CG   . LEU A 1 499 ? 114.327 103.060 83.963  1.00 62.26  ? 499 LEU A CG   1 
ATOM 7368 C CD1  . LEU A 1 499 ? 115.378 104.067 84.412  1.00 65.08  ? 499 LEU A CD1  1 
ATOM 7369 C CD2  . LEU A 1 499 ? 114.922 102.050 82.995  1.00 68.14  ? 499 LEU A CD2  1 
ATOM 7370 H H    . LEU A 1 499 ? 114.516 102.601 87.444  1.00 54.15  ? 499 LEU A H    1 
ATOM 7371 H HA   . LEU A 1 499 ? 113.076 104.152 85.920  1.00 51.02  ? 499 LEU A HA   1 
ATOM 7372 H HB2  . LEU A 1 499 ? 114.372 101.795 85.563  1.00 55.10  ? 499 LEU A HB2  1 
ATOM 7373 H HB3  . LEU A 1 499 ? 112.984 101.776 84.806  1.00 50.76  ? 499 LEU A HB3  1 
ATOM 7374 H HG   . LEU A 1 499 ? 113.637 103.549 83.488  1.00 59.15  ? 499 LEU A HG   1 
ATOM 7375 H HD11 . LEU A 1 499 ? 115.819 104.430 83.627  1.00 61.55  ? 499 LEU A HD11 1 
ATOM 7376 H HD12 . LEU A 1 499 ? 114.948 104.781 84.906  1.00 58.66  ? 499 LEU A HD12 1 
ATOM 7377 H HD13 . LEU A 1 499 ? 116.027 103.616 84.975  1.00 63.09  ? 499 LEU A HD13 1 
ATOM 7378 H HD21 . LEU A 1 499 ? 115.382 102.524 82.285  1.00 69.44  ? 499 LEU A HD21 1 
ATOM 7379 H HD22 . LEU A 1 499 ? 115.547 101.485 83.475  1.00 65.96  ? 499 LEU A HD22 1 
ATOM 7380 H HD23 . LEU A 1 499 ? 114.208 101.509 82.624  1.00 63.20  ? 499 LEU A HD23 1 
ATOM 7381 N N    . VAL A 1 500 ? 111.421 101.779 87.287  1.00 50.90  ? 500 VAL A N    1 
ATOM 7382 C CA   . VAL A 1 500 ? 110.057 101.357 87.604  1.00 46.43  ? 500 VAL A CA   1 
ATOM 7383 C C    . VAL A 1 500 ? 109.347 102.428 88.429  1.00 49.28  ? 500 VAL A C    1 
ATOM 7384 O O    . VAL A 1 500 ? 108.180 102.767 88.176  1.00 53.61  ? 500 VAL A O    1 
ATOM 7385 C CB   . VAL A 1 500 ? 110.073 100.001 88.332  1.00 45.00  ? 500 VAL A CB   1 
ATOM 7386 C CG1  . VAL A 1 500 ? 108.700 99.691  88.913  1.00 53.80  ? 500 VAL A CG1  1 
ATOM 7387 C CG2  . VAL A 1 500 ? 110.525 98.897  87.386  1.00 51.04  ? 500 VAL A CG2  1 
ATOM 7388 H H    . VAL A 1 500 ? 112.038 101.297 87.641  1.00 52.36  ? 500 VAL A H    1 
ATOM 7389 H HA   . VAL A 1 500 ? 109.564 101.244 86.776  1.00 48.86  ? 500 VAL A HA   1 
ATOM 7390 H HB   . VAL A 1 500 ? 110.706 100.044 89.066  1.00 49.23  ? 500 VAL A HB   1 
ATOM 7391 H HG11 . VAL A 1 500 ? 108.017 100.060 88.330  1.00 52.04  ? 500 VAL A HG11 1 
ATOM 7392 H HG12 . VAL A 1 500 ? 108.593 98.729  88.978  1.00 54.65  ? 500 VAL A HG12 1 
ATOM 7393 H HG13 . VAL A 1 500 ? 108.634 100.087 89.796  1.00 51.96  ? 500 VAL A HG13 1 
ATOM 7394 H HG21 . VAL A 1 500 ? 110.883 99.301  86.579  1.00 50.25  ? 500 VAL A HG21 1 
ATOM 7395 H HG22 . VAL A 1 500 ? 111.210 98.369  87.823  1.00 53.56  ? 500 VAL A HG22 1 
ATOM 7396 H HG23 . VAL A 1 500 ? 109.767 98.335  87.163  1.00 51.83  ? 500 VAL A HG23 1 
ATOM 7397 N N    . TYR A 1 501 ? 110.040 102.966 89.439  1.00 49.60  ? 501 TYR A N    1 
ATOM 7398 C CA   . TYR A 1 501 ? 109.446 103.992 90.291  1.00 50.43  ? 501 TYR A CA   1 
ATOM 7399 C C    . TYR A 1 501 ? 109.117 105.253 89.508  1.00 45.77  ? 501 TYR A C    1 
ATOM 7400 O O    . TYR A 1 501 ? 108.227 106.013 89.903  1.00 48.00  ? 501 TYR A O    1 
ATOM 7401 C CB   . TYR A 1 501 ? 110.389 104.339 91.444  1.00 50.90  ? 501 TYR A CB   1 
ATOM 7402 C CG   . TYR A 1 501 ? 110.509 103.273 92.510  1.00 47.72  ? 501 TYR A CG   1 
ATOM 7403 C CD1  . TYR A 1 501 ? 109.383 102.676 93.056  1.00 52.45  ? 501 TYR A CD1  1 
ATOM 7404 C CD2  . TYR A 1 501 ? 111.752 102.878 92.983  1.00 48.87  ? 501 TYR A CD2  1 
ATOM 7405 C CE1  . TYR A 1 501 ? 109.492 101.708 94.031  1.00 55.90  ? 501 TYR A CE1  1 
ATOM 7406 C CE2  . TYR A 1 501 ? 111.870 101.910 93.958  1.00 50.40  ? 501 TYR A CE2  1 
ATOM 7407 C CZ   . TYR A 1 501 ? 110.737 101.330 94.478  1.00 53.32  ? 501 TYR A CZ   1 
ATOM 7408 O OH   . TYR A 1 501 ? 110.850 100.366 95.451  1.00 60.22  ? 501 TYR A OH   1 
ATOM 7409 H H    . TYR A 1 501 ? 110.847 102.755 89.646  1.00 51.41  ? 501 TYR A H    1 
ATOM 7410 H HA   . TYR A 1 501 ? 108.618 103.652 90.664  1.00 50.44  ? 501 TYR A HA   1 
ATOM 7411 H HB2  . TYR A 1 501 ? 111.276 104.491 91.081  1.00 51.84  ? 501 TYR A HB2  1 
ATOM 7412 H HB3  . TYR A 1 501 ? 110.069 105.148 91.872  1.00 51.72  ? 501 TYR A HB3  1 
ATOM 7413 H HD1  . TYR A 1 501 ? 108.540 102.929 92.754  1.00 52.11  ? 501 TYR A HD1  1 
ATOM 7414 H HD2  . TYR A 1 501 ? 112.520 103.268 92.631  1.00 53.13  ? 501 TYR A HD2  1 
ATOM 7415 H HE1  . TYR A 1 501 ? 108.728 101.314 94.385  1.00 54.84  ? 501 TYR A HE1  1 
ATOM 7416 H HE2  . TYR A 1 501 ? 112.710 101.653 94.262  1.00 54.22  ? 501 TYR A HE2  1 
ATOM 7417 H HH   . TYR A 1 501 ? 110.086 100.111 95.692  1.00 57.06  ? 501 TYR A HH   1 
ATOM 7418 N N    . GLY A 1 502 ? 109.843 105.513 88.419  1.00 44.01  ? 502 GLY A N    1 
ATOM 7419 C CA   . GLY A 1 502 ? 109.532 106.662 87.591  1.00 41.18  ? 502 GLY A CA   1 
ATOM 7420 C C    . GLY A 1 502 ? 108.445 106.395 86.574  1.00 41.05  ? 502 GLY A C    1 
ATOM 7421 O O    . GLY A 1 502 ? 107.677 107.300 86.236  1.00 49.79  ? 502 GLY A O    1 
ATOM 7422 H H    . GLY A 1 502 ? 110.510 105.043 88.147  1.00 48.65  ? 502 GLY A H    1 
ATOM 7423 H HA2  . GLY A 1 502 ? 109.248 107.398 88.155  1.00 43.72  ? 502 GLY A HA2  1 
ATOM 7424 H HA3  . GLY A 1 502 ? 110.331 106.935 87.113  1.00 43.84  ? 502 GLY A HA3  1 
ATOM 7425 N N    . THR A 1 503 ? 108.359 105.162 86.073  1.00 36.48  ? 503 THR A N    1 
ATOM 7426 C CA   . THR A 1 503 ? 107.361 104.845 85.059  1.00 39.21  ? 503 THR A CA   1 
ATOM 7427 C C    . THR A 1 503 ? 105.968 104.703 85.658  1.00 41.32  ? 503 THR A C    1 
ATOM 7428 O O    . THR A 1 503 ? 104.981 105.085 85.021  1.00 43.35  ? 503 THR A O    1 
ATOM 7429 C CB   . THR A 1 503 ? 107.742 103.563 84.318  1.00 44.96  ? 503 THR A CB   1 
ATOM 7430 O OG1  . THR A 1 503 ? 108.041 102.530 85.265  1.00 51.59  ? 503 THR A OG1  1 
ATOM 7431 C CG2  . THR A 1 503 ? 108.947 103.800 83.416  1.00 51.69  ? 503 THR A CG2  1 
ATOM 7432 H H    . THR A 1 503 ? 108.861 104.501 86.300  1.00 42.63  ? 503 THR A H    1 
ATOM 7433 H HA   . THR A 1 503 ? 107.332 105.566 84.410  1.00 42.68  ? 503 THR A HA   1 
ATOM 7434 H HB   . THR A 1 503 ? 106.998 103.281 83.763  1.00 44.89  ? 503 THR A HB   1 
ATOM 7435 H HG1  . THR A 1 503 ? 107.359 102.353 85.721  1.00 47.92  ? 503 THR A HG1  1 
ATOM 7436 H HG21 . THR A 1 503 ? 109.680 104.172 83.930  1.00 50.39  ? 503 THR A HG21 1 
ATOM 7437 H HG22 . THR A 1 503 ? 109.232 102.962 83.019  1.00 48.75  ? 503 THR A HG22 1 
ATOM 7438 H HG23 . THR A 1 503 ? 108.712 104.421 82.709  1.00 47.80  ? 503 THR A HG23 1 
ATOM 7439 N N    . VAL A 1 504 ? 105.855 104.150 86.868  1.00 43.05  ? 504 VAL A N    1 
ATOM 7440 C CA   . VAL A 1 504 ? 104.529 103.942 87.456  1.00 42.34  ? 504 VAL A CA   1 
ATOM 7441 C C    . VAL A 1 504 ? 103.785 105.261 87.655  1.00 45.45  ? 504 VAL A C    1 
ATOM 7442 O O    . VAL A 1 504 ? 102.642 105.380 87.181  1.00 45.46  ? 504 VAL A O    1 
ATOM 7443 C CB   . VAL A 1 504 ? 104.648 103.125 88.751  1.00 45.51  ? 504 VAL A CB   1 
ATOM 7444 C CG1  . VAL A 1 504 ? 103.478 103.410 89.687  1.00 43.08  ? 504 VAL A CG1  1 
ATOM 7445 C CG2  . VAL A 1 504 ? 104.726 101.638 88.434  1.00 50.69  ? 504 VAL A CG2  1 
ATOM 7446 H H    . VAL A 1 504 ? 106.512 103.892 87.359  1.00 44.81  ? 504 VAL A H    1 
ATOM 7447 H HA   . VAL A 1 504 ? 104.002 103.418 86.831  1.00 42.83  ? 504 VAL A HA   1 
ATOM 7448 H HB   . VAL A 1 504 ? 105.467 103.367 89.210  1.00 46.53  ? 504 VAL A HB   1 
ATOM 7449 H HG11 . VAL A 1 504 ? 102.656 103.450 89.173  1.00 42.07  ? 504 VAL A HG11 1 
ATOM 7450 H HG12 . VAL A 1 504 ? 103.420 102.693 90.338  1.00 44.98  ? 504 VAL A HG12 1 
ATOM 7451 H HG13 . VAL A 1 504 ? 103.633 104.251 90.143  1.00 43.71  ? 504 VAL A HG13 1 
ATOM 7452 H HG21 . VAL A 1 504 ? 104.931 101.524 87.493  1.00 48.91  ? 504 VAL A HG21 1 
ATOM 7453 H HG22 . VAL A 1 504 ? 105.426 101.238 88.973  1.00 48.49  ? 504 VAL A HG22 1 
ATOM 7454 H HG23 . VAL A 1 504 ? 103.874 101.225 88.640  1.00 49.71  ? 504 VAL A HG23 1 
ATOM 7455 N N    . PRO A 1 505 ? 104.348 106.270 88.328  1.00 47.30  ? 505 PRO A N    1 
ATOM 7456 C CA   . PRO A 1 505 ? 103.599 107.523 88.519  1.00 38.52  ? 505 PRO A CA   1 
ATOM 7457 C C    . PRO A 1 505 ? 103.226 108.217 87.224  1.00 35.49  ? 505 PRO A C    1 
ATOM 7458 O O    . PRO A 1 505 ? 102.158 108.833 87.155  1.00 40.26  ? 505 PRO A O    1 
ATOM 7459 C CB   . PRO A 1 505 ? 104.560 108.377 89.357  1.00 35.76  ? 505 PRO A CB   1 
ATOM 7460 C CG   . PRO A 1 505 ? 105.423 107.400 90.050  1.00 41.98  ? 505 PRO A CG   1 
ATOM 7461 C CD   . PRO A 1 505 ? 105.613 106.277 89.079  1.00 47.78  ? 505 PRO A CD   1 
ATOM 7462 H HA   . PRO A 1 505 ? 102.795 107.355 89.035  1.00 40.40  ? 505 PRO A HA   1 
ATOM 7463 H HB2  . PRO A 1 505 ? 105.085 108.947 88.774  1.00 38.60  ? 505 PRO A HB2  1 
ATOM 7464 H HB3  . PRO A 1 505 ? 104.057 108.906 89.995  1.00 38.03  ? 505 PRO A HB3  1 
ATOM 7465 H HG2  . PRO A 1 505 ? 106.273 107.813 90.270  1.00 43.44  ? 505 PRO A HG2  1 
ATOM 7466 H HG3  . PRO A 1 505 ? 104.977 107.085 90.852  1.00 43.11  ? 505 PRO A HG3  1 
ATOM 7467 H HD2  . PRO A 1 505 ? 106.356 106.462 88.483  1.00 45.67  ? 505 PRO A HD2  1 
ATOM 7468 H HD3  . PRO A 1 505 ? 105.737 105.447 89.560  1.00 45.56  ? 505 PRO A HD3  1 
ATOM 7469 N N    . VAL A 1 506 ? 104.073 108.153 86.196  1.00 32.98  ? 506 VAL A N    1 
ATOM 7470 C CA   . VAL A 1 506 ? 103.754 108.821 84.937  1.00 33.64  ? 506 VAL A CA   1 
ATOM 7471 C C    . VAL A 1 506 ? 102.494 108.220 84.330  1.00 34.26  ? 506 VAL A C    1 
ATOM 7472 O O    . VAL A 1 506 ? 101.575 108.938 83.915  1.00 35.13  ? 506 VAL A O    1 
ATOM 7473 C CB   . VAL A 1 506 ? 104.946 108.730 83.966  1.00 33.91  ? 506 VAL A CB   1 
ATOM 7474 C CG1  . VAL A 1 506 ? 104.501 109.012 82.535  1.00 33.97  ? 506 VAL A CG1  1 
ATOM 7475 C CG2  . VAL A 1 506 ? 106.054 109.683 84.392  1.00 34.49  ? 506 VAL A CG2  1 
ATOM 7476 H H    . VAL A 1 506 ? 104.826 107.736 86.202  1.00 37.15  ? 506 VAL A H    1 
ATOM 7477 H HA   . VAL A 1 506 ? 103.582 109.759 85.113  1.00 34.64  ? 506 VAL A HA   1 
ATOM 7478 H HB   . VAL A 1 506 ? 105.303 107.829 83.994  1.00 37.43  ? 506 VAL A HB   1 
ATOM 7479 H HG11 . VAL A 1 506 ? 105.284 109.207 81.996  1.00 33.73  ? 506 VAL A HG11 1 
ATOM 7480 H HG12 . VAL A 1 506 ? 104.048 108.230 82.181  1.00 34.69  ? 506 VAL A HG12 1 
ATOM 7481 H HG13 . VAL A 1 506 ? 103.902 109.775 82.534  1.00 33.35  ? 506 VAL A HG13 1 
ATOM 7482 H HG21 . VAL A 1 506 ? 105.833 110.060 85.258  1.00 35.18  ? 506 VAL A HG21 1 
ATOM 7483 H HG22 . VAL A 1 506 ? 106.887 109.191 84.449  1.00 35.61  ? 506 VAL A HG22 1 
ATOM 7484 H HG23 . VAL A 1 506 ? 106.133 110.391 83.733  1.00 35.48  ? 506 VAL A HG23 1 
ATOM 7485 N N    . LEU A 1 507 ? 102.430 106.888 84.277  1.00 37.65  ? 507 LEU A N    1 
ATOM 7486 C CA   . LEU A 1 507 ? 101.250 106.230 83.729  1.00 42.34  ? 507 LEU A CA   1 
ATOM 7487 C C    . LEU A 1 507 ? 100.023 106.492 84.591  1.00 45.53  ? 507 LEU A C    1 
ATOM 7488 O O    . LEU A 1 507 ? 98.927  106.718 84.064  1.00 46.41  ? 507 LEU A O    1 
ATOM 7489 C CB   . LEU A 1 507 ? 101.502 104.729 83.592  1.00 41.61  ? 507 LEU A CB   1 
ATOM 7490 C CG   . LEU A 1 507 ? 102.364 104.309 82.398  1.00 44.80  ? 507 LEU A CG   1 
ATOM 7491 C CD1  . LEU A 1 507 ? 102.718 102.833 82.488  1.00 56.48  ? 507 LEU A CD1  1 
ATOM 7492 C CD2  . LEU A 1 507 ? 101.663 104.612 81.083  1.00 43.78  ? 507 LEU A CD2  1 
ATOM 7493 H H    . LEU A 1 507 ? 103.046 106.354 84.549  1.00 39.20  ? 507 LEU A H    1 
ATOM 7494 H HA   . LEU A 1 507 ? 101.073 106.590 82.846  1.00 41.76  ? 507 LEU A HA   1 
ATOM 7495 H HB2  . LEU A 1 507 ? 101.947 104.418 84.395  1.00 41.73  ? 507 LEU A HB2  1 
ATOM 7496 H HB3  . LEU A 1 507 ? 100.646 104.282 83.503  1.00 42.84  ? 507 LEU A HB3  1 
ATOM 7497 H HG   . LEU A 1 507 ? 103.191 104.815 82.417  1.00 42.30  ? 507 LEU A HG   1 
ATOM 7498 H HD11 . LEU A 1 507 ? 101.900 102.312 82.495  1.00 54.21  ? 507 LEU A HD11 1 
ATOM 7499 H HD12 . LEU A 1 507 ? 103.258 102.592 81.719  1.00 53.27  ? 507 LEU A HD12 1 
ATOM 7500 H HD13 . LEU A 1 507 ? 103.217 102.678 83.305  1.00 50.16  ? 507 LEU A HD13 1 
ATOM 7501 H HD21 . LEU A 1 507 ? 100.745 104.300 81.134  1.00 44.58  ? 507 LEU A HD21 1 
ATOM 7502 H HD22 . LEU A 1 507 ? 101.679 105.570 80.929  1.00 41.28  ? 507 LEU A HD22 1 
ATOM 7503 H HD23 . LEU A 1 507 ? 102.129 104.156 80.365  1.00 46.99  ? 507 LEU A HD23 1 
ATOM 7504 N N    . SER A 1 508 ? 100.182 106.467 85.917  1.00 45.60  ? 508 SER A N    1 
ATOM 7505 C CA   . SER A 1 508 ? 99.042  106.748 86.786  1.00 39.73  ? 508 SER A CA   1 
ATOM 7506 C C    . SER A 1 508 ? 98.506  108.157 86.554  1.00 36.62  ? 508 SER A C    1 
ATOM 7507 O O    . SER A 1 508 ? 97.289  108.361 86.461  1.00 34.17  ? 508 SER A O    1 
ATOM 7508 C CB   . SER A 1 508 ? 99.440  106.559 88.250  1.00 39.55  ? 508 SER A CB   1 
ATOM 7509 O OG   . SER A 1 508 ? 98.542  107.239 89.109  1.00 39.19  ? 508 SER A OG   1 
ATOM 7510 H H    . SER A 1 508 ? 100.919 106.297 86.327  1.00 42.48  ? 508 SER A H    1 
ATOM 7511 H HA   . SER A 1 508 ? 98.330  106.120 86.586  1.00 39.69  ? 508 SER A HA   1 
ATOM 7512 H HB2  . SER A 1 508 ? 99.423  105.613 88.461  1.00 40.28  ? 508 SER A HB2  1 
ATOM 7513 H HB3  . SER A 1 508 ? 100.333 106.914 88.382  1.00 39.33  ? 508 SER A HB3  1 
ATOM 7514 H HG   . SER A 1 508 ? 97.756  106.980 88.967  1.00 39.78  ? 508 SER A HG   1 
ATOM 7515 N N    . GLY A 1 509 ? 99.400  109.141 86.444  1.00 39.79  ? 509 GLY A N    1 
ATOM 7516 C CA   . GLY A 1 509 ? 98.960  110.503 86.199  1.00 38.10  ? 509 GLY A CA   1 
ATOM 7517 C C    . GLY A 1 509 ? 98.294  110.665 84.847  1.00 38.82  ? 509 GLY A C    1 
ATOM 7518 O O    . GLY A 1 509 ? 97.261  111.328 84.732  1.00 49.29  ? 509 GLY A O    1 
ATOM 7519 H H    . GLY A 1 509 ? 100.252 109.044 86.507  1.00 39.93  ? 509 GLY A H    1 
ATOM 7520 H HA2  . GLY A 1 509 ? 98.328  110.768 86.886  1.00 39.52  ? 509 GLY A HA2  1 
ATOM 7521 H HA3  . GLY A 1 509 ? 99.723  111.100 86.237  1.00 37.64  ? 509 GLY A HA3  1 
ATOM 7522 N N    . LEU A 1 510 ? 98.867  110.056 83.806  1.00 32.86  ? 510 LEU A N    1 
ATOM 7523 C CA   . LEU A 1 510 ? 98.239  110.127 82.491  1.00 36.06  ? 510 LEU A CA   1 
ATOM 7524 C C    . LEU A 1 510 ? 96.847  109.511 82.522  1.00 45.43  ? 510 LEU A C    1 
ATOM 7525 O O    . LEU A 1 510 ? 95.910  110.047 81.918  1.00 49.20  ? 510 LEU A O    1 
ATOM 7526 C CB   . LEU A 1 510 ? 99.110  109.430 81.446  1.00 40.99  ? 510 LEU A CB   1 
ATOM 7527 C CG   . LEU A 1 510 ? 100.378 110.171 81.013  1.00 44.95  ? 510 LEU A CG   1 
ATOM 7528 C CD1  . LEU A 1 510 ? 101.302 109.240 80.245  1.00 42.96  ? 510 LEU A CD1  1 
ATOM 7529 C CD2  . LEU A 1 510 ? 100.030 111.390 80.173  1.00 52.92  ? 510 LEU A CD2  1 
ATOM 7530 H H    . LEU A 1 510 ? 99.601  109.608 83.834  1.00 37.20  ? 510 LEU A H    1 
ATOM 7531 H HA   . LEU A 1 510 ? 98.148  111.058 82.235  1.00 37.77  ? 510 LEU A HA   1 
ATOM 7532 H HB2  . LEU A 1 510 ? 99.386  108.572 81.803  1.00 41.98  ? 510 LEU A HB2  1 
ATOM 7533 H HB3  . LEU A 1 510 ? 98.574  109.289 80.650  1.00 42.95  ? 510 LEU A HB3  1 
ATOM 7534 H HG   . LEU A 1 510 ? 100.850 110.477 81.803  1.00 41.85  ? 510 LEU A HG   1 
ATOM 7535 H HD11 . LEU A 1 510 ? 101.523 108.480 80.806  1.00 40.68  ? 510 LEU A HD11 1 
ATOM 7536 H HD12 . LEU A 1 510 ? 100.849 108.939 79.442  1.00 43.59  ? 510 LEU A HD12 1 
ATOM 7537 H HD13 . LEU A 1 510 ? 102.109 109.723 80.008  1.00 41.81  ? 510 LEU A HD13 1 
ATOM 7538 H HD21 . LEU A 1 510 ? 100.849 111.780 79.830  1.00 51.27  ? 510 LEU A HD21 1 
ATOM 7539 H HD22 . LEU A 1 510 ? 99.463  111.113 79.436  1.00 49.97  ? 510 LEU A HD22 1 
ATOM 7540 H HD23 . LEU A 1 510 ? 99.562  112.034 80.726  1.00 46.73  ? 510 LEU A HD23 1 
ATOM 7541 N N    . ALA A 1 511 ? 96.689  108.385 83.221  1.00 42.63  ? 511 ALA A N    1 
ATOM 7542 C CA   . ALA A 1 511 ? 95.374  107.761 83.325  1.00 41.26  ? 511 ALA A CA   1 
ATOM 7543 C C    . ALA A 1 511 ? 94.399  108.645 84.093  1.00 42.27  ? 511 ALA A C    1 
ATOM 7544 O O    . ALA A 1 511 ? 93.210  108.703 83.759  1.00 41.61  ? 511 ALA A O    1 
ATOM 7545 C CB   . ALA A 1 511 ? 95.495  106.392 83.992  1.00 47.69  ? 511 ALA A CB   1 
ATOM 7546 H H    . ALA A 1 511 ? 97.317  107.971 83.637  1.00 42.06  ? 511 ALA A H    1 
ATOM 7547 H HA   . ALA A 1 511 ? 95.018  107.629 82.432  1.00 41.14  ? 511 ALA A HA   1 
ATOM 7548 H HB1  . ALA A 1 511 ? 95.866  106.507 84.881  1.00 42.64  ? 511 ALA A HB1  1 
ATOM 7549 H HB2  . ALA A 1 511 ? 94.613  105.992 84.050  1.00 47.28  ? 511 ALA A HB2  1 
ATOM 7550 H HB3  . ALA A 1 511 ? 96.079  105.832 83.458  1.00 45.42  ? 511 ALA A HB3  1 
ATOM 7551 N N    . ALA A 1 512 ? 94.881  109.342 85.121  1.00 39.77  ? 512 ALA A N    1 
ATOM 7552 C CA   . ALA A 1 512 ? 94.012  110.174 85.956  1.00 37.69  ? 512 ALA A CA   1 
ATOM 7553 C C    . ALA A 1 512 ? 93.470  111.408 85.231  1.00 38.38  ? 512 ALA A C    1 
ATOM 7554 O O    . ALA A 1 512 ? 92.798  112.211 85.887  1.00 40.97  ? 512 ALA A O    1 
ATOM 7555 C CB   . ALA A 1 512 ? 94.763  110.607 87.214  1.00 37.39  ? 512 ALA A CB   1 
ATOM 7556 H H    . ALA A 1 512 ? 95.708  109.350 85.358  1.00 40.41  ? 512 ALA A H    1 
ATOM 7557 H HA   . ALA A 1 512 ? 93.251  109.643 86.236  1.00 39.65  ? 512 ALA A HA   1 
ATOM 7558 H HB1  . ALA A 1 512 ? 95.057  109.817 87.692  1.00 39.05  ? 512 ALA A HB1  1 
ATOM 7559 H HB2  . ALA A 1 512 ? 95.530  111.141 86.955  1.00 39.96  ? 512 ALA A HB2  1 
ATOM 7560 H HB3  . ALA A 1 512 ? 94.168  111.132 87.772  1.00 38.71  ? 512 ALA A HB3  1 
ATOM 7561 N N    . LEU A 1 513 ? 93.722  111.616 83.941  1.00 44.21  ? 513 LEU A N    1 
ATOM 7562 C CA   . LEU A 1 513 ? 93.160  112.744 83.212  1.00 44.99  ? 513 LEU A CA   1 
ATOM 7563 C C    . LEU A 1 513 ? 91.780  112.450 82.639  1.00 52.98  ? 513 LEU A C    1 
ATOM 7564 O O    . LEU A 1 513 ? 91.173  113.342 82.038  1.00 48.20  ? 513 LEU A O    1 
ATOM 7565 C CB   . LEU A 1 513 ? 94.099  113.158 82.072  1.00 47.40  ? 513 LEU A CB   1 
ATOM 7566 C CG   . LEU A 1 513 ? 95.242  114.123 82.406  1.00 48.06  ? 513 LEU A CG   1 
ATOM 7567 C CD1  . LEU A 1 513 ? 96.105  114.357 81.178  1.00 53.56  ? 513 LEU A CD1  1 
ATOM 7568 C CD2  . LEU A 1 513 ? 94.712  115.444 82.940  1.00 43.30  ? 513 LEU A CD2  1 
ATOM 7569 H H    . LEU A 1 513 ? 94.225  111.110 83.461  1.00 43.94  ? 513 LEU A H    1 
ATOM 7570 H HA   . LEU A 1 513 ? 93.072  113.496 83.818  1.00 42.50  ? 513 LEU A HA   1 
ATOM 7571 H HB2  . LEU A 1 513 ? 94.504  112.354 81.710  1.00 46.74  ? 513 LEU A HB2  1 
ATOM 7572 H HB3  . LEU A 1 513 ? 93.565  113.582 81.382  1.00 46.61  ? 513 LEU A HB3  1 
ATOM 7573 H HG   . LEU A 1 513 ? 95.800  113.724 83.092  1.00 45.24  ? 513 LEU A HG   1 
ATOM 7574 H HD11 . LEU A 1 513 ? 96.828  114.961 81.410  1.00 51.90  ? 513 LEU A HD11 1 
ATOM 7575 H HD12 . LEU A 1 513 ? 96.466  113.508 80.878  1.00 49.50  ? 513 LEU A HD12 1 
ATOM 7576 H HD13 . LEU A 1 513 ? 95.558  114.749 80.479  1.00 53.16  ? 513 LEU A HD13 1 
ATOM 7577 H HD21 . LEU A 1 513 ? 95.433  116.093 82.945  1.00 42.44  ? 513 LEU A HD21 1 
ATOM 7578 H HD22 . LEU A 1 513 ? 93.994  115.751 82.365  1.00 43.94  ? 513 LEU A HD22 1 
ATOM 7579 H HD23 . LEU A 1 513 ? 94.380  115.312 83.842  1.00 43.05  ? 513 LEU A HD23 1 
ATOM 7580 N N    . LEU A 1 514 ? 91.270  111.230 82.811  1.00 56.44  ? 514 LEU A N    1 
ATOM 7581 C CA   . LEU A 1 514 ? 90.023  110.823 82.176  1.00 50.49  ? 514 LEU A CA   1 
ATOM 7582 C C    . LEU A 1 514 ? 88.802  111.066 83.055  1.00 48.70  ? 514 LEU A C    1 
ATOM 7583 O O    . LEU A 1 514 ? 87.750  111.474 82.550  1.00 40.12  ? 514 LEU A O    1 
ATOM 7584 C CB   . LEU A 1 514 ? 90.097  109.342 81.795  1.00 46.57  ? 514 LEU A CB   1 
ATOM 7585 C CG   . LEU A 1 514 ? 90.708  109.029 80.428  1.00 58.07  ? 514 LEU A CG   1 
ATOM 7586 C CD1  . LEU A 1 514 ? 90.971  107.540 80.295  1.00 65.25  ? 514 LEU A CD1  1 
ATOM 7587 C CD2  . LEU A 1 514 ? 89.805  109.508 79.302  1.00 63.89  ? 514 LEU A CD2  1 
ATOM 7588 H H    . LEU A 1 514 ? 91.630  110.618 83.295  1.00 49.68  ? 514 LEU A H    1 
ATOM 7589 H HA   . LEU A 1 514 ? 89.907  111.335 81.361  1.00 50.33  ? 514 LEU A HA   1 
ATOM 7590 H HB2  . LEU A 1 514 ? 90.631  108.882 82.462  1.00 47.95  ? 514 LEU A HB2  1 
ATOM 7591 H HB3  . LEU A 1 514 ? 89.197  108.981 81.799  1.00 50.35  ? 514 LEU A HB3  1 
ATOM 7592 H HG   . LEU A 1 514 ? 91.557  109.491 80.348  1.00 54.73  ? 514 LEU A HG   1 
ATOM 7593 H HD11 . LEU A 1 514 ? 91.590  107.266 80.990  1.00 59.14  ? 514 LEU A HD11 1 
ATOM 7594 H HD12 . LEU A 1 514 ? 90.133  107.062 80.390  1.00 62.39  ? 514 LEU A HD12 1 
ATOM 7595 H HD13 . LEU A 1 514 ? 91.355  107.366 79.422  1.00 62.34  ? 514 LEU A HD13 1 
ATOM 7596 H HD21 . LEU A 1 514 ? 90.135  109.154 78.461  1.00 63.21  ? 514 LEU A HD21 1 
ATOM 7597 H HD22 . LEU A 1 514 ? 88.903  109.190 79.464  1.00 59.88  ? 514 LEU A HD22 1 
ATOM 7598 H HD23 . LEU A 1 514 ? 89.814  110.478 79.279  1.00 59.89  ? 514 LEU A HD23 1 
ATOM 7599 N N    . LEU A 1 515 ? 88.912  110.824 84.359  1.00 50.18  ? 515 LEU A N    1 
ATOM 7600 C CA   . LEU A 1 515 ? 87.756  110.942 85.232  1.00 49.01  ? 515 LEU A CA   1 
ATOM 7601 C C    . LEU A 1 515 ? 87.281  112.395 85.293  1.00 49.11  ? 515 LEU A C    1 
ATOM 7602 O O    . LEU A 1 515 ? 88.082  113.325 85.160  1.00 46.47  ? 515 LEU A O    1 
ATOM 7603 C CB   . LEU A 1 515 ? 88.091  110.429 86.632  1.00 43.77  ? 515 LEU A CB   1 
ATOM 7604 C CG   . LEU A 1 515 ? 88.883  111.342 87.568  1.00 40.48  ? 515 LEU A CG   1 
ATOM 7605 C CD1  . LEU A 1 515 ? 89.044  110.682 88.927  1.00 44.70  ? 515 LEU A CD1  1 
ATOM 7606 C CD2  . LEU A 1 515 ? 90.235  111.679 86.978  1.00 40.99  ? 515 LEU A CD2  1 
ATOM 7607 H H    . LEU A 1 515 ? 89.638  110.590 84.755  1.00 47.54  ? 515 LEU A H    1 
ATOM 7608 H HA   . LEU A 1 515 ? 87.038  110.397 84.874  1.00 48.48  ? 515 LEU A HA   1 
ATOM 7609 H HB2  . LEU A 1 515 ? 87.258  110.219 87.082  1.00 45.05  ? 515 LEU A HB2  1 
ATOM 7610 H HB3  . LEU A 1 515 ? 88.608  109.614 86.532  1.00 45.54  ? 515 LEU A HB3  1 
ATOM 7611 H HG   . LEU A 1 515 ? 88.396  112.171 87.697  1.00 44.09  ? 515 LEU A HG   1 
ATOM 7612 H HD11 . LEU A 1 515 ? 88.166  110.506 89.298  1.00 47.33  ? 515 LEU A HD11 1 
ATOM 7613 H HD12 . LEU A 1 515 ? 89.530  109.849 88.816  1.00 45.47  ? 515 LEU A HD12 1 
ATOM 7614 H HD13 . LEU A 1 515 ? 89.539  111.279 89.511  1.00 45.80  ? 515 LEU A HD13 1 
ATOM 7615 H HD21 . LEU A 1 515 ? 90.684  110.856 86.728  1.00 42.36  ? 515 LEU A HD21 1 
ATOM 7616 H HD22 . LEU A 1 515 ? 90.108  112.237 86.195  1.00 43.72  ? 515 LEU A HD22 1 
ATOM 7617 H HD23 . LEU A 1 515 ? 90.759  112.155 87.641  1.00 42.85  ? 515 LEU A HD23 1 
ATOM 7618 N N    . PRO A 1 516 ? 85.985  112.618 85.499  1.00 60.72  ? 516 PRO A N    1 
ATOM 7619 C CA   . PRO A 1 516 ? 85.442  113.975 85.384  1.00 55.71  ? 516 PRO A CA   1 
ATOM 7620 C C    . PRO A 1 516 ? 85.954  114.898 86.479  1.00 54.20  ? 516 PRO A C    1 
ATOM 7621 O O    . PRO A 1 516 ? 86.398  114.470 87.546  1.00 58.31  ? 516 PRO A O    1 
ATOM 7622 C CB   . PRO A 1 516 ? 83.929  113.764 85.501  1.00 62.30  ? 516 PRO A CB   1 
ATOM 7623 C CG   . PRO A 1 516 ? 83.783  112.501 86.270  1.00 65.12  ? 516 PRO A CG   1 
ATOM 7624 C CD   . PRO A 1 516 ? 84.952  111.640 85.884  1.00 64.40  ? 516 PRO A CD   1 
ATOM 7625 H HA   . PRO A 1 516 ? 85.647  114.352 84.514  1.00 53.48  ? 516 PRO A HA   1 
ATOM 7626 H HB2  . PRO A 1 516 ? 83.529  114.507 85.981  1.00 59.95  ? 516 PRO A HB2  1 
ATOM 7627 H HB3  . PRO A 1 516 ? 83.540  113.675 84.617  1.00 60.81  ? 516 PRO A HB3  1 
ATOM 7628 H HG2  . PRO A 1 516 ? 83.803  112.696 87.220  1.00 59.63  ? 516 PRO A HG2  1 
ATOM 7629 H HG3  . PRO A 1 516 ? 82.949  112.069 86.029  1.00 60.75  ? 516 PRO A HG3  1 
ATOM 7630 H HD2  . PRO A 1 516 ? 85.246  111.117 86.646  1.00 57.05  ? 516 PRO A HD2  1 
ATOM 7631 H HD3  . PRO A 1 516 ? 84.720  111.076 85.130  1.00 59.26  ? 516 PRO A HD3  1 
ATOM 7632 N N    . GLU A 1 517 ? 85.878  116.194 86.190  1.00 52.65  ? 517 GLU A N    1 
ATOM 7633 C CA   . GLU A 1 517 ? 86.327  117.218 87.117  1.00 67.08  ? 517 GLU A CA   1 
ATOM 7634 C C    . GLU A 1 517 ? 85.369  117.328 88.299  1.00 70.64  ? 517 GLU A C    1 
ATOM 7635 O O    . GLU A 1 517 ? 84.197  116.948 88.224  1.00 73.07  ? 517 GLU A O    1 
ATOM 7636 C CB   . GLU A 1 517 ? 86.440  118.569 86.410  1.00 72.07  ? 517 GLU A CB   1 
ATOM 7637 C CG   . GLU A 1 517 ? 87.057  119.666 87.261  1.00 67.71  ? 517 GLU A CG   1 
ATOM 7638 C CD   . GLU A 1 517 ? 87.604  120.809 86.429  1.00 69.71  ? 517 GLU A CD   1 
ATOM 7639 O OE1  . GLU A 1 517 ? 86.801  121.643 85.960  1.00 66.69  ? 517 GLU A OE1  1 
ATOM 7640 O OE2  . GLU A 1 517 ? 88.836  120.874 86.244  1.00 70.05  ? 517 GLU A OE2  1 
ATOM 7641 H H    . GLU A 1 517 ? 85.566  116.507 85.452  1.00 55.47  ? 517 GLU A H    1 
ATOM 7642 H HA   . GLU A 1 517 ? 87.203  116.979 87.457  1.00 61.45  ? 517 GLU A HA   1 
ATOM 7643 H HB2  . GLU A 1 517 ? 86.992  118.462 85.620  1.00 66.70  ? 517 GLU A HB2  1 
ATOM 7644 H HB3  . GLU A 1 517 ? 85.551  118.860 86.152  1.00 68.88  ? 517 GLU A HB3  1 
ATOM 7645 H HG2  . GLU A 1 517 ? 86.379  120.024 87.855  1.00 66.97  ? 517 GLU A HG2  1 
ATOM 7646 H HG3  . GLU A 1 517 ? 87.788  119.293 87.777  1.00 62.52  ? 517 GLU A HG3  1 
ATOM 7647 N N    . THR A 1 518 ? 85.889  117.855 89.403  1.00 70.22  ? 518 THR A N    1 
ATOM 7648 C CA   . THR A 1 518 ? 85.108  118.019 90.623  1.00 73.63  ? 518 THR A CA   1 
ATOM 7649 C C    . THR A 1 518 ? 84.592  116.670 91.110  1.00 74.74  ? 518 THR A C    1 
ATOM 7650 O O    . THR A 1 518 ? 84.864  116.262 92.238  1.00 72.27  ? 518 THR A O    1 
ATOM 7651 C CB   . THR A 1 518 ? 83.915  118.973 90.412  1.00 70.36  ? 518 THR A CB   1 
ATOM 7652 O OG1  . THR A 1 518 ? 84.395  120.268 90.028  1.00 72.06  ? 518 THR A OG1  1 
ATOM 7653 C CG2  . THR A 1 518 ? 83.099  119.100 91.688  1.00 65.10  ? 518 THR A CG2  1 
ATOM 7654 H H    . THR A 1 518 ? 86.701  118.130 89.471  1.00 66.07  ? 518 THR A H    1 
ATOM 7655 H HA   . THR A 1 518 ? 85.675  118.394 91.315  1.00 70.39  ? 518 THR A HA   1 
ATOM 7656 H HB   . THR A 1 518 ? 83.338  118.624 89.716  1.00 69.12  ? 518 THR A HB   1 
ATOM 7657 H HG1  . THR A 1 518 ? 84.892  120.581 90.629  1.00 71.57  ? 518 THR A HG1  1 
ATOM 7658 H HG21 . THR A 1 518 ? 82.556  118.307 91.817  1.00 67.63  ? 518 THR A HG21 1 
ATOM 7659 H HG22 . THR A 1 518 ? 83.689  119.206 92.450  1.00 66.57  ? 518 THR A HG22 1 
ATOM 7660 H HG23 . THR A 1 518 ? 82.515  119.872 91.631  1.00 67.95  ? 518 THR A HG23 1 
# 
