data_9DIP
# 
_entry.id   9DIP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DIP         pdb_00009dip 10.2210/pdb9dip/pdb 
WWPDB D_1000288211 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-12-04 
2 'Structure model' 1 1 2024-12-11 
3 'Structure model' 1 2 2024-12-18 
4 'Structure model' 1 3 2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Structure summary'   
2 3 'Structure model' 'Database references' 
3 4 'Structure model' 'Data collection'     
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' struct          
2 3 'Structure model' citation        
3 3 'Structure model' citation_author 
4 4 'Structure model' diffrn_source   
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_struct.title'                            
2  3 'Structure model' '_citation.journal_volume'                 
3  3 'Structure model' '_citation.page_first'                     
4  3 'Structure model' '_citation.page_last'                      
5  3 'Structure model' '_citation.pdbx_database_id_PubMed'        
6  3 'Structure model' '_citation.title'                          
7  3 'Structure model' '_citation_author.name'                    
8  4 'Structure model' '_diffrn_source.pdbx_synchrotron_beamline' 
9  4 'Structure model' '_diffrn_source.pdbx_synchrotron_site'     
10 4 'Structure model' '_diffrn_source.type'                      
# 
loop_
_database_PDB_caveat.id 
_database_PDB_caveat.text 
1 'GLC F 1 HAS WRONG CHIRALITY AT ATOM C1' 
2 'GLC H 1 HAS WRONG CHIRALITY AT ATOM C1' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DIP 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-05 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              wilson@scripps.edu 
_pdbx_contact_author.name_first         Ian 
_pdbx_contact_author.name_last          Wilson 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6469-2419 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lin, T.H.'    1 ? 
'Zhu, Y.'      2 ? 
'Wilson, I.A.' 3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Science 
_citation.journal_id_ASTM           SCIEAS 
_citation.journal_id_CSD            0038 
_citation.journal_id_ISSN           1095-9203 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            386 
_citation.language                  ? 
_citation.page_first                1128 
_citation.page_last                 1134 
_citation.title                     
'A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/science.adt0180 
_citation.pdbx_database_id_PubMed   39636969 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lin, T.H.'     1 ? 
primary 'Zhu, X.'       2 ? 
primary 'Wang, S.'      3 ? 
primary 'Zhang, D.'     4 ? 
primary 'McBride, R.'   5 ? 
primary 'Yu, W.'        6 ? 
primary 'Babarinde, S.' 7 ? 
primary 'Paulson, J.C.' 8 ? 
primary 'Wilson, I.A.'  9 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Hemagglutinin HA1' 36534.414 3   ? ? ? ? 
2 polymer     man 'Hemagglutinin HA2' 20257.311 3   ? ? ? ? 
3 branched    man 
;N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose
;
836.744   1   ? ? ? ? 
4 branched    man 
;N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
;
998.885   2   ? ? ? ? 
5 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   1   ? ? ? ? 
6 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   2   ? ? ? ? 
7 water       nat water 18.015    141 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;ADPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEW
SYIVERANPANDLCYPGSLNDYEELKHMLSRINHFEKIQIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKNDA
YPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPITYISVGTSTLNQRLAPKIATRSQVNGQRGRMDFFWTILKPN
DAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATG
LRNSP
;
;ADPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEW
SYIVERANPANDLCYPGSLNDYEELKHMLSRINHFEKIQIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKNDA
YPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPITYISVGTSTLNQRLAPKIATRSQVNGQRGRMDFFWTILKPN
DAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATG
LRNSP
;
A,C,I ? 
2 'polypeptide(L)' no no 
;GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENL
NKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYP
QYSEEARLKREEISSG
;
;GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENL
NKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYP
QYSEEARLKREEISSG
;
B,D,J ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
6 2-acetamido-2-deoxy-beta-D-glucopyranose NAG 
7 water                                    HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   ASP n 
1 3   PRO n 
1 4   GLY n 
1 5   ASP n 
1 6   GLN n 
1 7   ILE n 
1 8   CYS n 
1 9   ILE n 
1 10  GLY n 
1 11  TYR n 
1 12  HIS n 
1 13  ALA n 
1 14  ASN n 
1 15  ASN n 
1 16  SER n 
1 17  THR n 
1 18  GLU n 
1 19  GLN n 
1 20  VAL n 
1 21  ASP n 
1 22  THR n 
1 23  ILE n 
1 24  MET n 
1 25  GLU n 
1 26  LYS n 
1 27  ASN n 
1 28  VAL n 
1 29  THR n 
1 30  VAL n 
1 31  THR n 
1 32  HIS n 
1 33  ALA n 
1 34  GLN n 
1 35  ASP n 
1 36  ILE n 
1 37  LEU n 
1 38  GLU n 
1 39  LYS n 
1 40  THR n 
1 41  HIS n 
1 42  ASN n 
1 43  GLY n 
1 44  LYS n 
1 45  LEU n 
1 46  CYS n 
1 47  ASP n 
1 48  LEU n 
1 49  ASN n 
1 50  GLY n 
1 51  VAL n 
1 52  LYS n 
1 53  PRO n 
1 54  LEU n 
1 55  ILE n 
1 56  LEU n 
1 57  LYS n 
1 58  ASP n 
1 59  CYS n 
1 60  SER n 
1 61  VAL n 
1 62  ALA n 
1 63  GLY n 
1 64  TRP n 
1 65  LEU n 
1 66  LEU n 
1 67  GLY n 
1 68  ASN n 
1 69  PRO n 
1 70  MET n 
1 71  CYS n 
1 72  ASP n 
1 73  GLU n 
1 74  PHE n 
1 75  ILE n 
1 76  ARG n 
1 77  VAL n 
1 78  PRO n 
1 79  GLU n 
1 80  TRP n 
1 81  SER n 
1 82  TYR n 
1 83  ILE n 
1 84  VAL n 
1 85  GLU n 
1 86  ARG n 
1 87  ALA n 
1 88  ASN n 
1 89  PRO n 
1 90  ALA n 
1 91  ASN n 
1 92  ASP n 
1 93  LEU n 
1 94  CYS n 
1 95  TYR n 
1 96  PRO n 
1 97  GLY n 
1 98  SER n 
1 99  LEU n 
1 100 ASN n 
1 101 ASP n 
1 102 TYR n 
1 103 GLU n 
1 104 GLU n 
1 105 LEU n 
1 106 LYS n 
1 107 HIS n 
1 108 MET n 
1 109 LEU n 
1 110 SER n 
1 111 ARG n 
1 112 ILE n 
1 113 ASN n 
1 114 HIS n 
1 115 PHE n 
1 116 GLU n 
1 117 LYS n 
1 118 ILE n 
1 119 GLN n 
1 120 ILE n 
1 121 ILE n 
1 122 PRO n 
1 123 LYS n 
1 124 SER n 
1 125 SER n 
1 126 TRP n 
1 127 PRO n 
1 128 ASN n 
1 129 HIS n 
1 130 GLU n 
1 131 THR n 
1 132 SER n 
1 133 LEU n 
1 134 GLY n 
1 135 VAL n 
1 136 SER n 
1 137 ALA n 
1 138 ALA n 
1 139 CYS n 
1 140 PRO n 
1 141 TYR n 
1 142 GLN n 
1 143 GLY n 
1 144 ALA n 
1 145 PRO n 
1 146 SER n 
1 147 PHE n 
1 148 PHE n 
1 149 ARG n 
1 150 ASN n 
1 151 VAL n 
1 152 VAL n 
1 153 TRP n 
1 154 LEU n 
1 155 ILE n 
1 156 LYS n 
1 157 LYS n 
1 158 ASN n 
1 159 ASP n 
1 160 ALA n 
1 161 TYR n 
1 162 PRO n 
1 163 THR n 
1 164 ILE n 
1 165 LYS n 
1 166 ILE n 
1 167 SER n 
1 168 TYR n 
1 169 ASN n 
1 170 ASN n 
1 171 THR n 
1 172 ASN n 
1 173 ARG n 
1 174 GLU n 
1 175 ASP n 
1 176 LEU n 
1 177 LEU n 
1 178 ILE n 
1 179 LEU n 
1 180 TRP n 
1 181 GLY n 
1 182 ILE n 
1 183 HIS n 
1 184 HIS n 
1 185 SER n 
1 186 ASN n 
1 187 ASN n 
1 188 ALA n 
1 189 GLU n 
1 190 GLU n 
1 191 GLN n 
1 192 THR n 
1 193 ASN n 
1 194 LEU n 
1 195 TYR n 
1 196 LYS n 
1 197 ASN n 
1 198 PRO n 
1 199 ILE n 
1 200 THR n 
1 201 TYR n 
1 202 ILE n 
1 203 SER n 
1 204 VAL n 
1 205 GLY n 
1 206 THR n 
1 207 SER n 
1 208 THR n 
1 209 LEU n 
1 210 ASN n 
1 211 GLN n 
1 212 ARG n 
1 213 LEU n 
1 214 ALA n 
1 215 PRO n 
1 216 LYS n 
1 217 ILE n 
1 218 ALA n 
1 219 THR n 
1 220 ARG n 
1 221 SER n 
1 222 GLN n 
1 223 VAL n 
1 224 ASN n 
1 225 GLY n 
1 226 GLN n 
1 227 ARG n 
1 228 GLY n 
1 229 ARG n 
1 230 MET n 
1 231 ASP n 
1 232 PHE n 
1 233 PHE n 
1 234 TRP n 
1 235 THR n 
1 236 ILE n 
1 237 LEU n 
1 238 LYS n 
1 239 PRO n 
1 240 ASN n 
1 241 ASP n 
1 242 ALA n 
1 243 ILE n 
1 244 HIS n 
1 245 PHE n 
1 246 GLU n 
1 247 SER n 
1 248 ASN n 
1 249 GLY n 
1 250 ASN n 
1 251 PHE n 
1 252 ILE n 
1 253 ALA n 
1 254 PRO n 
1 255 GLU n 
1 256 TYR n 
1 257 ALA n 
1 258 TYR n 
1 259 LYS n 
1 260 ILE n 
1 261 VAL n 
1 262 LYS n 
1 263 LYS n 
1 264 GLY n 
1 265 ASP n 
1 266 SER n 
1 267 THR n 
1 268 ILE n 
1 269 MET n 
1 270 LYS n 
1 271 SER n 
1 272 GLY n 
1 273 VAL n 
1 274 GLU n 
1 275 TYR n 
1 276 GLY n 
1 277 HIS n 
1 278 CYS n 
1 279 ASN n 
1 280 THR n 
1 281 LYS n 
1 282 CYS n 
1 283 GLN n 
1 284 THR n 
1 285 PRO n 
1 286 VAL n 
1 287 GLY n 
1 288 ALA n 
1 289 ILE n 
1 290 ASN n 
1 291 SER n 
1 292 SER n 
1 293 MET n 
1 294 PRO n 
1 295 PHE n 
1 296 HIS n 
1 297 ASN n 
1 298 ILE n 
1 299 HIS n 
1 300 PRO n 
1 301 LEU n 
1 302 THR n 
1 303 ILE n 
1 304 GLY n 
1 305 GLU n 
1 306 CYS n 
1 307 PRO n 
1 308 LYS n 
1 309 TYR n 
1 310 VAL n 
1 311 LYS n 
1 312 SER n 
1 313 ASN n 
1 314 LYS n 
1 315 LEU n 
1 316 VAL n 
1 317 LEU n 
1 318 ALA n 
1 319 THR n 
1 320 GLY n 
1 321 LEU n 
1 322 ARG n 
1 323 ASN n 
1 324 SER n 
1 325 PRO n 
2 1   GLY n 
2 2   LEU n 
2 3   PHE n 
2 4   GLY n 
2 5   ALA n 
2 6   ILE n 
2 7   ALA n 
2 8   GLY n 
2 9   PHE n 
2 10  ILE n 
2 11  GLU n 
2 12  GLY n 
2 13  GLY n 
2 14  TRP n 
2 15  GLN n 
2 16  GLY n 
2 17  MET n 
2 18  VAL n 
2 19  ASP n 
2 20  GLY n 
2 21  TRP n 
2 22  TYR n 
2 23  GLY n 
2 24  TYR n 
2 25  HIS n 
2 26  HIS n 
2 27  SER n 
2 28  ASN n 
2 29  GLU n 
2 30  GLN n 
2 31  GLY n 
2 32  SER n 
2 33  GLY n 
2 34  TYR n 
2 35  ALA n 
2 36  ALA n 
2 37  ASP n 
2 38  LYS n 
2 39  GLU n 
2 40  SER n 
2 41  THR n 
2 42  GLN n 
2 43  LYS n 
2 44  ALA n 
2 45  ILE n 
2 46  ASP n 
2 47  GLY n 
2 48  VAL n 
2 49  THR n 
2 50  ASN n 
2 51  LYS n 
2 52  VAL n 
2 53  ASN n 
2 54  SER n 
2 55  ILE n 
2 56  ILE n 
2 57  ASP n 
2 58  LYS n 
2 59  MET n 
2 60  ASN n 
2 61  THR n 
2 62  GLN n 
2 63  PHE n 
2 64  GLU n 
2 65  ALA n 
2 66  VAL n 
2 67  GLY n 
2 68  ARG n 
2 69  GLU n 
2 70  PHE n 
2 71  ASN n 
2 72  ASN n 
2 73  LEU n 
2 74  GLU n 
2 75  ARG n 
2 76  ARG n 
2 77  ILE n 
2 78  GLU n 
2 79  ASN n 
2 80  LEU n 
2 81  ASN n 
2 82  LYS n 
2 83  LYS n 
2 84  MET n 
2 85  GLU n 
2 86  ASP n 
2 87  GLY n 
2 88  PHE n 
2 89  LEU n 
2 90  ASP n 
2 91  VAL n 
2 92  TRP n 
2 93  THR n 
2 94  TYR n 
2 95  ASN n 
2 96  ALA n 
2 97  GLU n 
2 98  LEU n 
2 99  LEU n 
2 100 VAL n 
2 101 LEU n 
2 102 MET n 
2 103 GLU n 
2 104 ASN n 
2 105 GLU n 
2 106 ARG n 
2 107 THR n 
2 108 LEU n 
2 109 ASP n 
2 110 PHE n 
2 111 HIS n 
2 112 ASP n 
2 113 SER n 
2 114 ASN n 
2 115 VAL n 
2 116 LYS n 
2 117 ASN n 
2 118 LEU n 
2 119 TYR n 
2 120 ASP n 
2 121 LYS n 
2 122 VAL n 
2 123 ARG n 
2 124 LEU n 
2 125 GLN n 
2 126 LEU n 
2 127 ARG n 
2 128 ASP n 
2 129 ASN n 
2 130 ALA n 
2 131 LYS n 
2 132 GLU n 
2 133 LEU n 
2 134 GLY n 
2 135 ASN n 
2 136 GLY n 
2 137 CYS n 
2 138 PHE n 
2 139 GLU n 
2 140 PHE n 
2 141 TYR n 
2 142 HIS n 
2 143 LYS n 
2 144 CYS n 
2 145 ASP n 
2 146 ASN n 
2 147 GLU n 
2 148 CYS n 
2 149 MET n 
2 150 GLU n 
2 151 SER n 
2 152 VAL n 
2 153 ARG n 
2 154 ASN n 
2 155 GLY n 
2 156 THR n 
2 157 TYR n 
2 158 ASP n 
2 159 TYR n 
2 160 PRO n 
2 161 GLN n 
2 162 TYR n 
2 163 SER n 
2 164 GLU n 
2 165 GLU n 
2 166 ALA n 
2 167 ARG n 
2 168 LEU n 
2 169 LYS n 
2 170 ARG n 
2 171 GLU n 
2 172 GLU n 
2 173 ILE n 
2 174 SER n 
2 175 SER n 
2 176 GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 325 ? ? HA ? ? ? ? ? ? 'Influenza A virus' 11320 ? ? ? ? ? ? ? ? 
'Spodoptera aff. frugiperda 1 BOLD-2017' 2449148 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 176 ? ? HA ? ? ? ? ? ? 'Influenza A virus' 11320 ? ? ? ? ? ? ? ? 
'Spodoptera aff. frugiperda 1 BOLD-2017' 2449148 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
3 oligosaccharide 
4 oligosaccharide 
5 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 3 DNeup5Aca2-3DGalpb1-3DGlcpNAcb1-3DGalpb1-ROH 'Glycam Condensed Sequence' GMML       1.0   
2 3 'WURCS=2.0/3,4,3/[a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-1-3/a3-b1_b3-c1_c3-d2' WURCS 
PDB2Glycan 1.1.0 
3 3 '[][b-D-Galp]{[(3+1)][b-D-GlcpNAc]{[(3+1)][b-D-Galp]{[(3+2)][a-D-Neup5Ac]{}}}}' LINUCS                      PDB-CARE   ?     
4 4 DNeup5Aca2-3DGalpb1-3DGlcpNAcb1-3DGalpb1-4DGlcpa1-ROH 'Glycam Condensed Sequence' GMML       1.0   
5 4 
;WURCS=2.0/4,5,4/[a2122h-1a_1-5][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-2-4/a4-b1_b3-c1_c3-d1_d3-e2
;
WURCS                       PDB2Glycan 1.1.0 
6 4 '[][b-D-Glcp]{[(4+1)][b-D-Galp]{[(3+1)][b-D-GlcpNAc]{[(3+1)][b-D-Galp]{[(3+2)][a-D-Neup5Ac]{}}}}}' LINUCS                      
PDB-CARE   ?     
7 5 DGlcpNAcb1-4DGlcpNAcb1-ROH 'Glycam Condensed Sequence' GMML       1.0   
8 5 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
9 5 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}' LINUCS                      PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 3 2 NAG C1 O1 1 GAL O3 HO3 sing ? 
2 3 3 GAL C1 O1 2 NAG O3 HO3 sing ? 
3 3 4 SIA C2 O2 3 GAL O3 HO3 sing ? 
4 4 2 GAL C1 O1 1 GLC O4 HO4 sing ? 
5 4 3 NAG C1 O1 2 GAL O3 HO3 sing ? 
6 4 4 GAL C1 O1 3 NAG O3 HO3 sing ? 
7 4 5 SIA C2 O2 4 GAL O3 HO3 sing ? 
8 5 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GAL 'D-saccharide, beta linking'  . beta-D-galactopyranose                   'beta-D-galactose; D-galactose; galactose' 
'C6 H12 O6'      180.156 
GLC 'D-saccharide, alpha linking' . alpha-D-glucopyranose                    'alpha-D-glucose; D-glucose; glucose' 'C6 H12 O6' 
180.156 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                                    ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
SIA 'D-saccharide, alpha linking' . 'N-acetyl-alpha-neuraminic acid'         
'N-acetylneuraminic acid; sialic acid; alpha-sialic acid; O-SIALIC ACID' 'C11 H19 N O9'   309.270 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
GAL 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpb                         
GAL 'COMMON NAME'                         GMML     1.0 b-D-galactopyranose            
GAL 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Galp                       
GAL 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Gal                            
GLC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpa                         
GLC 'COMMON NAME'                         GMML     1.0 a-D-glucopyranose              
GLC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Glcp                       
GLC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Glc                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
SIA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DNeup5Aca                      
SIA 'COMMON NAME'                         GMML     1.0 'N-acetyl-a-D-neuraminic acid' 
SIA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Neup5Ac                    
SIA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Neu5Ac                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   7   ?   ?   ?   A . n 
A 1 2   ASP 2   8   ?   ?   ?   A . n 
A 1 3   PRO 3   9   ?   ?   ?   A . n 
A 1 4   GLY 4   10  10  GLY GLY A . n 
A 1 5   ASP 5   11  11  ASP ASP A . n 
A 1 6   GLN 6   12  12  GLN GLN A . n 
A 1 7   ILE 7   13  13  ILE ILE A . n 
A 1 8   CYS 8   14  14  CYS CYS A . n 
A 1 9   ILE 9   15  15  ILE ILE A . n 
A 1 10  GLY 10  16  16  GLY GLY A . n 
A 1 11  TYR 11  17  17  TYR TYR A . n 
A 1 12  HIS 12  18  18  HIS HIS A . n 
A 1 13  ALA 13  19  19  ALA ALA A . n 
A 1 14  ASN 14  20  20  ASN ASN A . n 
A 1 15  ASN 15  21  21  ASN ASN A . n 
A 1 16  SER 16  22  22  SER SER A . n 
A 1 17  THR 17  23  23  THR THR A . n 
A 1 18  GLU 18  24  24  GLU GLU A . n 
A 1 19  GLN 19  25  25  GLN GLN A . n 
A 1 20  VAL 20  26  26  VAL VAL A . n 
A 1 21  ASP 21  27  27  ASP ASP A . n 
A 1 22  THR 22  28  28  THR THR A . n 
A 1 23  ILE 23  29  29  ILE ILE A . n 
A 1 24  MET 24  30  30  MET MET A . n 
A 1 25  GLU 25  31  31  GLU GLU A . n 
A 1 26  LYS 26  32  32  LYS LYS A . n 
A 1 27  ASN 27  33  33  ASN ASN A . n 
A 1 28  VAL 28  34  34  VAL VAL A . n 
A 1 29  THR 29  35  35  THR THR A . n 
A 1 30  VAL 30  36  36  VAL VAL A . n 
A 1 31  THR 31  37  37  THR THR A . n 
A 1 32  HIS 32  38  38  HIS HIS A . n 
A 1 33  ALA 33  39  39  ALA ALA A . n 
A 1 34  GLN 34  40  40  GLN GLN A . n 
A 1 35  ASP 35  41  41  ASP ASP A . n 
A 1 36  ILE 36  42  42  ILE ILE A . n 
A 1 37  LEU 37  43  43  LEU LEU A . n 
A 1 38  GLU 38  44  44  GLU GLU A . n 
A 1 39  LYS 39  45  45  LYS LYS A . n 
A 1 40  THR 40  46  46  THR THR A . n 
A 1 41  HIS 41  47  47  HIS HIS A . n 
A 1 42  ASN 42  48  48  ASN ASN A . n 
A 1 43  GLY 43  49  49  GLY GLY A . n 
A 1 44  LYS 44  50  50  LYS LYS A . n 
A 1 45  LEU 45  51  51  LEU LEU A . n 
A 1 46  CYS 46  52  52  CYS CYS A . n 
A 1 47  ASP 47  53  53  ASP ASP A . n 
A 1 48  LEU 48  54  54  LEU LEU A . n 
A 1 49  ASN 49  55  55  ASN ASN A . n 
A 1 50  GLY 50  55  55  GLY GLY A A n 
A 1 51  VAL 51  56  56  VAL VAL A . n 
A 1 52  LYS 52  57  57  LYS LYS A . n 
A 1 53  PRO 53  58  58  PRO PRO A . n 
A 1 54  LEU 54  59  59  LEU LEU A . n 
A 1 55  ILE 55  60  60  ILE ILE A . n 
A 1 56  LEU 56  61  61  LEU LEU A . n 
A 1 57  LYS 57  62  62  LYS LYS A . n 
A 1 58  ASP 58  63  63  ASP ASP A . n 
A 1 59  CYS 59  64  64  CYS CYS A . n 
A 1 60  SER 60  65  65  SER SER A . n 
A 1 61  VAL 61  66  66  VAL VAL A . n 
A 1 62  ALA 62  67  67  ALA ALA A . n 
A 1 63  GLY 63  68  68  GLY GLY A . n 
A 1 64  TRP 64  69  69  TRP TRP A . n 
A 1 65  LEU 65  70  70  LEU LEU A . n 
A 1 66  LEU 66  71  71  LEU LEU A . n 
A 1 67  GLY 67  72  72  GLY GLY A . n 
A 1 68  ASN 68  73  73  ASN ASN A . n 
A 1 69  PRO 69  74  74  PRO PRO A . n 
A 1 70  MET 70  75  75  MET MET A . n 
A 1 71  CYS 71  76  76  CYS CYS A . n 
A 1 72  ASP 72  77  77  ASP ASP A . n 
A 1 73  GLU 73  78  78  GLU GLU A . n 
A 1 74  PHE 74  79  79  PHE PHE A . n 
A 1 75  ILE 75  80  80  ILE ILE A . n 
A 1 76  ARG 76  81  81  ARG ARG A . n 
A 1 77  VAL 77  82  82  VAL VAL A . n 
A 1 78  PRO 78  83  83  PRO PRO A . n 
A 1 79  GLU 79  83  83  GLU GLU A A n 
A 1 80  TRP 80  84  84  TRP TRP A . n 
A 1 81  SER 81  85  85  SER SER A . n 
A 1 82  TYR 82  86  86  TYR TYR A . n 
A 1 83  ILE 83  87  87  ILE ILE A . n 
A 1 84  VAL 84  88  88  VAL VAL A . n 
A 1 85  GLU 85  89  89  GLU GLU A . n 
A 1 86  ARG 86  90  90  ARG ARG A . n 
A 1 87  ALA 87  91  91  ALA ALA A . n 
A 1 88  ASN 88  92  92  ASN ASN A . n 
A 1 89  PRO 89  93  93  PRO PRO A . n 
A 1 90  ALA 90  94  94  ALA ALA A . n 
A 1 91  ASN 91  95  95  ASN ASN A . n 
A 1 92  ASP 92  96  96  ASP ASP A . n 
A 1 93  LEU 93  96  96  LEU LEU A A n 
A 1 94  CYS 94  97  97  CYS CYS A . n 
A 1 95  TYR 95  98  98  TYR TYR A . n 
A 1 96  PRO 96  99  99  PRO PRO A . n 
A 1 97  GLY 97  100 100 GLY GLY A . n 
A 1 98  SER 98  101 101 SER SER A . n 
A 1 99  LEU 99  102 102 LEU LEU A . n 
A 1 100 ASN 100 103 103 ASN ASN A . n 
A 1 101 ASP 101 104 104 ASP ASP A . n 
A 1 102 TYR 102 105 105 TYR TYR A . n 
A 1 103 GLU 103 106 106 GLU GLU A . n 
A 1 104 GLU 104 107 107 GLU GLU A . n 
A 1 105 LEU 105 108 108 LEU LEU A . n 
A 1 106 LYS 106 109 109 LYS LYS A . n 
A 1 107 HIS 107 110 110 HIS HIS A . n 
A 1 108 MET 108 111 111 MET MET A . n 
A 1 109 LEU 109 112 112 LEU LEU A . n 
A 1 110 SER 110 113 113 SER SER A . n 
A 1 111 ARG 111 114 114 ARG ARG A . n 
A 1 112 ILE 112 115 115 ILE ILE A . n 
A 1 113 ASN 113 116 116 ASN ASN A . n 
A 1 114 HIS 114 117 117 HIS HIS A . n 
A 1 115 PHE 115 118 118 PHE PHE A . n 
A 1 116 GLU 116 119 119 GLU GLU A . n 
A 1 117 LYS 117 120 120 LYS LYS A . n 
A 1 118 ILE 118 121 121 ILE ILE A . n 
A 1 119 GLN 119 122 122 GLN GLN A . n 
A 1 120 ILE 120 123 123 ILE ILE A . n 
A 1 121 ILE 121 124 124 ILE ILE A . n 
A 1 122 PRO 122 125 125 PRO PRO A . n 
A 1 123 LYS 123 125 125 LYS LYS A A n 
A 1 124 SER 124 125 125 SER SER A B n 
A 1 125 SER 125 126 126 SER SER A . n 
A 1 126 TRP 126 127 127 TRP TRP A . n 
A 1 127 PRO 127 128 128 PRO PRO A . n 
A 1 128 ASN 128 129 129 ASN ASN A . n 
A 1 129 HIS 129 130 130 HIS HIS A . n 
A 1 130 GLU 130 131 131 GLU GLU A . n 
A 1 131 THR 131 132 132 THR THR A . n 
A 1 132 SER 132 133 133 SER SER A . n 
A 1 133 LEU 133 133 133 LEU LEU A A n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 SER 136 136 136 SER SER A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 CYS 139 139 139 CYS CYS A . n 
A 1 140 PRO 140 140 140 PRO PRO A . n 
A 1 141 TYR 141 141 141 TYR TYR A . n 
A 1 142 GLN 142 142 142 GLN GLN A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 PRO 145 145 145 PRO PRO A . n 
A 1 146 SER 146 146 146 SER SER A . n 
A 1 147 PHE 147 147 147 PHE PHE A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 ASN 150 150 150 ASN ASN A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 VAL 152 152 152 VAL VAL A . n 
A 1 153 TRP 153 153 153 TRP TRP A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 ILE 155 155 155 ILE ILE A . n 
A 1 156 LYS 156 156 156 LYS LYS A . n 
A 1 157 LYS 157 157 157 LYS LYS A . n 
A 1 158 ASN 158 158 158 ASN ASN A . n 
A 1 159 ASP 159 159 159 ASP ASP A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 TYR 161 161 161 TYR TYR A . n 
A 1 162 PRO 162 162 162 PRO PRO A . n 
A 1 163 THR 163 163 163 THR THR A . n 
A 1 164 ILE 164 164 164 ILE ILE A . n 
A 1 165 LYS 165 165 165 LYS LYS A . n 
A 1 166 ILE 166 166 166 ILE ILE A . n 
A 1 167 SER 167 167 167 SER SER A . n 
A 1 168 TYR 168 168 168 TYR TYR A . n 
A 1 169 ASN 169 169 169 ASN ASN A . n 
A 1 170 ASN 170 170 170 ASN ASN A . n 
A 1 171 THR 171 171 171 THR THR A . n 
A 1 172 ASN 172 172 172 ASN ASN A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 ASP 175 175 175 ASP ASP A . n 
A 1 176 LEU 176 176 176 LEU LEU A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 TRP 180 180 180 TRP TRP A . n 
A 1 181 GLY 181 181 181 GLY GLY A . n 
A 1 182 ILE 182 182 182 ILE ILE A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 HIS 184 184 184 HIS HIS A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 GLU 189 189 189 GLU GLU A . n 
A 1 190 GLU 190 190 190 GLU GLU A . n 
A 1 191 GLN 191 191 191 GLN GLN A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 ASN 193 193 193 ASN ASN A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 TYR 195 195 195 TYR TYR A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 ASN 197 197 197 ASN ASN A . n 
A 1 198 PRO 198 198 198 PRO PRO A . n 
A 1 199 ILE 199 199 199 ILE ILE A . n 
A 1 200 THR 200 200 200 THR THR A . n 
A 1 201 TYR 201 201 201 TYR TYR A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 GLY 205 205 205 GLY GLY A . n 
A 1 206 THR 206 206 206 THR THR A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 LEU 209 209 209 LEU LEU A . n 
A 1 210 ASN 210 210 210 ASN ASN A . n 
A 1 211 GLN 211 211 211 GLN GLN A . n 
A 1 212 ARG 212 212 212 ARG ARG A . n 
A 1 213 LEU 213 213 213 LEU LEU A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 PRO 215 215 215 PRO PRO A . n 
A 1 216 LYS 216 216 216 LYS LYS A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 ARG 220 220 220 ARG ARG A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 VAL 223 223 223 VAL VAL A . n 
A 1 224 ASN 224 224 224 ASN ASN A . n 
A 1 225 GLY 225 225 225 GLY GLY A . n 
A 1 226 GLN 226 226 226 GLN GLN A . n 
A 1 227 ARG 227 227 227 ARG ARG A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 MET 230 230 230 MET MET A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 PHE 232 232 232 PHE PHE A . n 
A 1 233 PHE 233 233 233 PHE PHE A . n 
A 1 234 TRP 234 234 234 TRP TRP A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 ILE 236 236 236 ILE ILE A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 LYS 238 238 238 LYS LYS A . n 
A 1 239 PRO 239 239 239 PRO PRO A . n 
A 1 240 ASN 240 240 240 ASN ASN A . n 
A 1 241 ASP 241 241 241 ASP ASP A . n 
A 1 242 ALA 242 242 242 ALA ALA A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 HIS 244 244 244 HIS HIS A . n 
A 1 245 PHE 245 245 245 PHE PHE A . n 
A 1 246 GLU 246 246 246 GLU GLU A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 GLY 249 249 249 GLY GLY A . n 
A 1 250 ASN 250 250 250 ASN ASN A . n 
A 1 251 PHE 251 251 251 PHE PHE A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 ALA 253 253 253 ALA ALA A . n 
A 1 254 PRO 254 254 254 PRO PRO A . n 
A 1 255 GLU 255 255 255 GLU GLU A . n 
A 1 256 TYR 256 256 256 TYR TYR A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 TYR 258 258 258 TYR TYR A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 ILE 260 260 260 ILE ILE A . n 
A 1 261 VAL 261 260 260 VAL VAL A A n 
A 1 262 LYS 262 261 261 LYS LYS A . n 
A 1 263 LYS 263 262 262 LYS LYS A . n 
A 1 264 GLY 264 263 263 GLY GLY A . n 
A 1 265 ASP 265 264 264 ASP ASP A . n 
A 1 266 SER 266 265 265 SER SER A . n 
A 1 267 THR 267 266 266 THR THR A . n 
A 1 268 ILE 268 267 267 ILE ILE A . n 
A 1 269 MET 269 268 268 MET MET A . n 
A 1 270 LYS 270 269 269 LYS LYS A . n 
A 1 271 SER 271 270 270 SER SER A . n 
A 1 272 GLY 272 271 271 GLY GLY A . n 
A 1 273 VAL 273 272 272 VAL VAL A . n 
A 1 274 GLU 274 273 273 GLU GLU A . n 
A 1 275 TYR 275 274 274 TYR TYR A . n 
A 1 276 GLY 276 275 275 GLY GLY A . n 
A 1 277 HIS 277 276 276 HIS HIS A . n 
A 1 278 CYS 278 277 277 CYS CYS A . n 
A 1 279 ASN 279 278 278 ASN ASN A . n 
A 1 280 THR 280 279 279 THR THR A . n 
A 1 281 LYS 281 280 280 LYS LYS A . n 
A 1 282 CYS 282 281 281 CYS CYS A . n 
A 1 283 GLN 283 282 282 GLN GLN A . n 
A 1 284 THR 284 283 283 THR THR A . n 
A 1 285 PRO 285 284 284 PRO PRO A . n 
A 1 286 VAL 286 285 285 VAL VAL A . n 
A 1 287 GLY 287 286 286 GLY GLY A . n 
A 1 288 ALA 288 287 287 ALA ALA A . n 
A 1 289 ILE 289 288 288 ILE ILE A . n 
A 1 290 ASN 290 289 289 ASN ASN A . n 
A 1 291 SER 291 290 290 SER SER A . n 
A 1 292 SER 292 291 291 SER SER A . n 
A 1 293 MET 293 292 292 MET MET A . n 
A 1 294 PRO 294 293 293 PRO PRO A . n 
A 1 295 PHE 295 294 294 PHE PHE A . n 
A 1 296 HIS 296 295 295 HIS HIS A . n 
A 1 297 ASN 297 296 296 ASN ASN A . n 
A 1 298 ILE 298 297 297 ILE ILE A . n 
A 1 299 HIS 299 298 298 HIS HIS A . n 
A 1 300 PRO 300 299 299 PRO PRO A . n 
A 1 301 LEU 301 300 300 LEU LEU A . n 
A 1 302 THR 302 301 301 THR THR A . n 
A 1 303 ILE 303 302 302 ILE ILE A . n 
A 1 304 GLY 304 303 303 GLY GLY A . n 
A 1 305 GLU 305 304 304 GLU GLU A . n 
A 1 306 CYS 306 305 305 CYS CYS A . n 
A 1 307 PRO 307 306 306 PRO PRO A . n 
A 1 308 LYS 308 307 307 LYS LYS A . n 
A 1 309 TYR 309 308 308 TYR TYR A . n 
A 1 310 VAL 310 309 309 VAL VAL A . n 
A 1 311 LYS 311 310 310 LYS LYS A . n 
A 1 312 SER 312 311 311 SER SER A . n 
A 1 313 ASN 313 312 312 ASN ASN A . n 
A 1 314 LYS 314 313 313 LYS LYS A . n 
A 1 315 LEU 315 314 314 LEU LEU A . n 
A 1 316 VAL 316 315 315 VAL VAL A . n 
A 1 317 LEU 317 316 316 LEU LEU A . n 
A 1 318 ALA 318 317 317 ALA ALA A . n 
A 1 319 THR 319 318 318 THR THR A . n 
A 1 320 GLY 320 319 319 GLY GLY A . n 
A 1 321 LEU 321 320 320 LEU LEU A . n 
A 1 322 ARG 322 321 321 ARG ARG A . n 
A 1 323 ASN 323 322 322 ASN ASN A . n 
A 1 324 SER 324 323 323 SER SER A . n 
A 1 325 PRO 325 324 324 PRO PRO A . n 
B 2 1   GLY 1   1   1   GLY GLY B . n 
B 2 2   LEU 2   2   2   LEU LEU B . n 
B 2 3   PHE 3   3   3   PHE PHE B . n 
B 2 4   GLY 4   4   4   GLY GLY B . n 
B 2 5   ALA 5   5   5   ALA ALA B . n 
B 2 6   ILE 6   6   6   ILE ILE B . n 
B 2 7   ALA 7   7   7   ALA ALA B . n 
B 2 8   GLY 8   8   8   GLY GLY B . n 
B 2 9   PHE 9   9   9   PHE PHE B . n 
B 2 10  ILE 10  10  10  ILE ILE B . n 
B 2 11  GLU 11  11  11  GLU GLU B . n 
B 2 12  GLY 12  12  12  GLY GLY B . n 
B 2 13  GLY 13  13  13  GLY GLY B . n 
B 2 14  TRP 14  14  14  TRP TRP B . n 
B 2 15  GLN 15  15  15  GLN GLN B . n 
B 2 16  GLY 16  16  16  GLY GLY B . n 
B 2 17  MET 17  17  17  MET MET B . n 
B 2 18  VAL 18  18  18  VAL VAL B . n 
B 2 19  ASP 19  19  19  ASP ASP B . n 
B 2 20  GLY 20  20  20  GLY GLY B . n 
B 2 21  TRP 21  21  21  TRP TRP B . n 
B 2 22  TYR 22  22  22  TYR TYR B . n 
B 2 23  GLY 23  23  23  GLY GLY B . n 
B 2 24  TYR 24  24  24  TYR TYR B . n 
B 2 25  HIS 25  25  25  HIS HIS B . n 
B 2 26  HIS 26  26  26  HIS HIS B . n 
B 2 27  SER 27  27  27  SER SER B . n 
B 2 28  ASN 28  28  28  ASN ASN B . n 
B 2 29  GLU 29  29  29  GLU GLU B . n 
B 2 30  GLN 30  30  30  GLN GLN B . n 
B 2 31  GLY 31  31  31  GLY GLY B . n 
B 2 32  SER 32  32  32  SER SER B . n 
B 2 33  GLY 33  33  33  GLY GLY B . n 
B 2 34  TYR 34  34  34  TYR TYR B . n 
B 2 35  ALA 35  35  35  ALA ALA B . n 
B 2 36  ALA 36  36  36  ALA ALA B . n 
B 2 37  ASP 37  37  37  ASP ASP B . n 
B 2 38  LYS 38  38  38  LYS LYS B . n 
B 2 39  GLU 39  39  39  GLU GLU B . n 
B 2 40  SER 40  40  40  SER SER B . n 
B 2 41  THR 41  41  41  THR THR B . n 
B 2 42  GLN 42  42  42  GLN GLN B . n 
B 2 43  LYS 43  43  43  LYS LYS B . n 
B 2 44  ALA 44  44  44  ALA ALA B . n 
B 2 45  ILE 45  45  45  ILE ILE B . n 
B 2 46  ASP 46  46  46  ASP ASP B . n 
B 2 47  GLY 47  47  47  GLY GLY B . n 
B 2 48  VAL 48  48  48  VAL VAL B . n 
B 2 49  THR 49  49  49  THR THR B . n 
B 2 50  ASN 50  50  50  ASN ASN B . n 
B 2 51  LYS 51  51  51  LYS LYS B . n 
B 2 52  VAL 52  52  52  VAL VAL B . n 
B 2 53  ASN 53  53  53  ASN ASN B . n 
B 2 54  SER 54  54  54  SER SER B . n 
B 2 55  ILE 55  55  55  ILE ILE B . n 
B 2 56  ILE 56  56  56  ILE ILE B . n 
B 2 57  ASP 57  57  57  ASP ASP B . n 
B 2 58  LYS 58  58  58  LYS LYS B . n 
B 2 59  MET 59  59  59  MET MET B . n 
B 2 60  ASN 60  60  60  ASN ASN B . n 
B 2 61  THR 61  61  61  THR THR B . n 
B 2 62  GLN 62  62  62  GLN GLN B . n 
B 2 63  PHE 63  63  63  PHE PHE B . n 
B 2 64  GLU 64  64  64  GLU GLU B . n 
B 2 65  ALA 65  65  65  ALA ALA B . n 
B 2 66  VAL 66  66  66  VAL VAL B . n 
B 2 67  GLY 67  67  67  GLY GLY B . n 
B 2 68  ARG 68  68  68  ARG ARG B . n 
B 2 69  GLU 69  69  69  GLU GLU B . n 
B 2 70  PHE 70  70  70  PHE PHE B . n 
B 2 71  ASN 71  71  71  ASN ASN B . n 
B 2 72  ASN 72  72  72  ASN ASN B . n 
B 2 73  LEU 73  73  73  LEU LEU B . n 
B 2 74  GLU 74  74  74  GLU GLU B . n 
B 2 75  ARG 75  75  75  ARG ARG B . n 
B 2 76  ARG 76  76  76  ARG ARG B . n 
B 2 77  ILE 77  77  77  ILE ILE B . n 
B 2 78  GLU 78  78  78  GLU GLU B . n 
B 2 79  ASN 79  79  79  ASN ASN B . n 
B 2 80  LEU 80  80  80  LEU LEU B . n 
B 2 81  ASN 81  81  81  ASN ASN B . n 
B 2 82  LYS 82  82  82  LYS LYS B . n 
B 2 83  LYS 83  83  83  LYS LYS B . n 
B 2 84  MET 84  84  84  MET MET B . n 
B 2 85  GLU 85  85  85  GLU GLU B . n 
B 2 86  ASP 86  86  86  ASP ASP B . n 
B 2 87  GLY 87  87  87  GLY GLY B . n 
B 2 88  PHE 88  88  88  PHE PHE B . n 
B 2 89  LEU 89  89  89  LEU LEU B . n 
B 2 90  ASP 90  90  90  ASP ASP B . n 
B 2 91  VAL 91  91  91  VAL VAL B . n 
B 2 92  TRP 92  92  92  TRP TRP B . n 
B 2 93  THR 93  93  93  THR THR B . n 
B 2 94  TYR 94  94  94  TYR TYR B . n 
B 2 95  ASN 95  95  95  ASN ASN B . n 
B 2 96  ALA 96  96  96  ALA ALA B . n 
B 2 97  GLU 97  97  97  GLU GLU B . n 
B 2 98  LEU 98  98  98  LEU LEU B . n 
B 2 99  LEU 99  99  99  LEU LEU B . n 
B 2 100 VAL 100 100 100 VAL VAL B . n 
B 2 101 LEU 101 101 101 LEU LEU B . n 
B 2 102 MET 102 102 102 MET MET B . n 
B 2 103 GLU 103 103 103 GLU GLU B . n 
B 2 104 ASN 104 104 104 ASN ASN B . n 
B 2 105 GLU 105 105 105 GLU GLU B . n 
B 2 106 ARG 106 106 106 ARG ARG B . n 
B 2 107 THR 107 107 107 THR THR B . n 
B 2 108 LEU 108 108 108 LEU LEU B . n 
B 2 109 ASP 109 109 109 ASP ASP B . n 
B 2 110 PHE 110 110 110 PHE PHE B . n 
B 2 111 HIS 111 111 111 HIS HIS B . n 
B 2 112 ASP 112 112 112 ASP ASP B . n 
B 2 113 SER 113 113 113 SER SER B . n 
B 2 114 ASN 114 114 114 ASN ASN B . n 
B 2 115 VAL 115 115 115 VAL VAL B . n 
B 2 116 LYS 116 116 116 LYS LYS B . n 
B 2 117 ASN 117 117 117 ASN ASN B . n 
B 2 118 LEU 118 118 118 LEU LEU B . n 
B 2 119 TYR 119 119 119 TYR TYR B . n 
B 2 120 ASP 120 120 120 ASP ASP B . n 
B 2 121 LYS 121 121 121 LYS LYS B . n 
B 2 122 VAL 122 122 122 VAL VAL B . n 
B 2 123 ARG 123 123 123 ARG ARG B . n 
B 2 124 LEU 124 124 124 LEU LEU B . n 
B 2 125 GLN 125 125 125 GLN GLN B . n 
B 2 126 LEU 126 126 126 LEU LEU B . n 
B 2 127 ARG 127 127 127 ARG ARG B . n 
B 2 128 ASP 128 128 128 ASP ASP B . n 
B 2 129 ASN 129 129 129 ASN ASN B . n 
B 2 130 ALA 130 130 130 ALA ALA B . n 
B 2 131 LYS 131 131 131 LYS LYS B . n 
B 2 132 GLU 132 132 132 GLU GLU B . n 
B 2 133 LEU 133 133 133 LEU LEU B . n 
B 2 134 GLY 134 134 134 GLY GLY B . n 
B 2 135 ASN 135 135 135 ASN ASN B . n 
B 2 136 GLY 136 136 136 GLY GLY B . n 
B 2 137 CYS 137 137 137 CYS CYS B . n 
B 2 138 PHE 138 138 138 PHE PHE B . n 
B 2 139 GLU 139 139 139 GLU GLU B . n 
B 2 140 PHE 140 140 140 PHE PHE B . n 
B 2 141 TYR 141 141 141 TYR TYR B . n 
B 2 142 HIS 142 142 142 HIS HIS B . n 
B 2 143 LYS 143 143 143 LYS LYS B . n 
B 2 144 CYS 144 144 144 CYS CYS B . n 
B 2 145 ASP 145 145 145 ASP ASP B . n 
B 2 146 ASN 146 146 146 ASN ASN B . n 
B 2 147 GLU 147 147 147 GLU GLU B . n 
B 2 148 CYS 148 148 148 CYS CYS B . n 
B 2 149 MET 149 149 149 MET MET B . n 
B 2 150 GLU 150 150 150 GLU GLU B . n 
B 2 151 SER 151 151 151 SER SER B . n 
B 2 152 VAL 152 152 152 VAL VAL B . n 
B 2 153 ARG 153 153 153 ARG ARG B . n 
B 2 154 ASN 154 154 154 ASN ASN B . n 
B 2 155 GLY 155 155 155 GLY GLY B . n 
B 2 156 THR 156 156 156 THR THR B . n 
B 2 157 TYR 157 157 157 TYR TYR B . n 
B 2 158 ASP 158 158 158 ASP ASP B . n 
B 2 159 TYR 159 159 159 TYR TYR B . n 
B 2 160 PRO 160 160 160 PRO PRO B . n 
B 2 161 GLN 161 161 161 GLN GLN B . n 
B 2 162 TYR 162 162 162 TYR TYR B . n 
B 2 163 SER 163 163 163 SER SER B . n 
B 2 164 GLU 164 164 164 GLU GLU B . n 
B 2 165 GLU 165 165 165 GLU GLU B . n 
B 2 166 ALA 166 166 166 ALA ALA B . n 
B 2 167 ARG 167 167 167 ARG ARG B . n 
B 2 168 LEU 168 168 168 LEU LEU B . n 
B 2 169 LYS 169 169 169 LYS LYS B . n 
B 2 170 ARG 170 170 170 ARG ARG B . n 
B 2 171 GLU 171 171 171 GLU GLU B . n 
B 2 172 GLU 172 172 172 GLU GLU B . n 
B 2 173 ILE 173 173 173 ILE ILE B . n 
B 2 174 SER 174 174 174 SER SER B . n 
B 2 175 SER 175 175 ?   ?   ?   B . n 
B 2 176 GLY 176 176 ?   ?   ?   B . n 
C 1 1   ALA 1   7   ?   ?   ?   C . n 
C 1 2   ASP 2   8   ?   ?   ?   C . n 
C 1 3   PRO 3   9   ?   ?   ?   C . n 
C 1 4   GLY 4   10  10  GLY GLY C . n 
C 1 5   ASP 5   11  11  ASP ASP C . n 
C 1 6   GLN 6   12  12  GLN GLN C . n 
C 1 7   ILE 7   13  13  ILE ILE C . n 
C 1 8   CYS 8   14  14  CYS CYS C . n 
C 1 9   ILE 9   15  15  ILE ILE C . n 
C 1 10  GLY 10  16  16  GLY GLY C . n 
C 1 11  TYR 11  17  17  TYR TYR C . n 
C 1 12  HIS 12  18  18  HIS HIS C . n 
C 1 13  ALA 13  19  19  ALA ALA C . n 
C 1 14  ASN 14  20  20  ASN ASN C . n 
C 1 15  ASN 15  21  21  ASN ASN C . n 
C 1 16  SER 16  22  22  SER SER C . n 
C 1 17  THR 17  23  23  THR THR C . n 
C 1 18  GLU 18  24  24  GLU GLU C . n 
C 1 19  GLN 19  25  25  GLN GLN C . n 
C 1 20  VAL 20  26  26  VAL VAL C . n 
C 1 21  ASP 21  27  27  ASP ASP C . n 
C 1 22  THR 22  28  28  THR THR C . n 
C 1 23  ILE 23  29  29  ILE ILE C . n 
C 1 24  MET 24  30  30  MET MET C . n 
C 1 25  GLU 25  31  31  GLU GLU C . n 
C 1 26  LYS 26  32  32  LYS LYS C . n 
C 1 27  ASN 27  33  33  ASN ASN C . n 
C 1 28  VAL 28  34  34  VAL VAL C . n 
C 1 29  THR 29  35  35  THR THR C . n 
C 1 30  VAL 30  36  36  VAL VAL C . n 
C 1 31  THR 31  37  37  THR THR C . n 
C 1 32  HIS 32  38  38  HIS HIS C . n 
C 1 33  ALA 33  39  39  ALA ALA C . n 
C 1 34  GLN 34  40  40  GLN GLN C . n 
C 1 35  ASP 35  41  41  ASP ASP C . n 
C 1 36  ILE 36  42  42  ILE ILE C . n 
C 1 37  LEU 37  43  43  LEU LEU C . n 
C 1 38  GLU 38  44  44  GLU GLU C . n 
C 1 39  LYS 39  45  45  LYS LYS C . n 
C 1 40  THR 40  46  46  THR THR C . n 
C 1 41  HIS 41  47  47  HIS HIS C . n 
C 1 42  ASN 42  48  48  ASN ASN C . n 
C 1 43  GLY 43  49  49  GLY GLY C . n 
C 1 44  LYS 44  50  50  LYS LYS C . n 
C 1 45  LEU 45  51  51  LEU LEU C . n 
C 1 46  CYS 46  52  52  CYS CYS C . n 
C 1 47  ASP 47  53  53  ASP ASP C . n 
C 1 48  LEU 48  54  54  LEU LEU C . n 
C 1 49  ASN 49  55  55  ASN ASN C . n 
C 1 50  GLY 50  55  55  GLY GLY C A n 
C 1 51  VAL 51  56  56  VAL VAL C . n 
C 1 52  LYS 52  57  57  LYS LYS C . n 
C 1 53  PRO 53  58  58  PRO PRO C . n 
C 1 54  LEU 54  59  59  LEU LEU C . n 
C 1 55  ILE 55  60  60  ILE ILE C . n 
C 1 56  LEU 56  61  61  LEU LEU C . n 
C 1 57  LYS 57  62  62  LYS LYS C . n 
C 1 58  ASP 58  63  63  ASP ASP C . n 
C 1 59  CYS 59  64  64  CYS CYS C . n 
C 1 60  SER 60  65  65  SER SER C . n 
C 1 61  VAL 61  66  66  VAL VAL C . n 
C 1 62  ALA 62  67  67  ALA ALA C . n 
C 1 63  GLY 63  68  68  GLY GLY C . n 
C 1 64  TRP 64  69  69  TRP TRP C . n 
C 1 65  LEU 65  70  70  LEU LEU C . n 
C 1 66  LEU 66  71  71  LEU LEU C . n 
C 1 67  GLY 67  72  72  GLY GLY C . n 
C 1 68  ASN 68  73  73  ASN ASN C . n 
C 1 69  PRO 69  74  74  PRO PRO C . n 
C 1 70  MET 70  75  75  MET MET C . n 
C 1 71  CYS 71  76  76  CYS CYS C . n 
C 1 72  ASP 72  77  77  ASP ASP C . n 
C 1 73  GLU 73  78  78  GLU GLU C . n 
C 1 74  PHE 74  79  79  PHE PHE C . n 
C 1 75  ILE 75  80  80  ILE ILE C . n 
C 1 76  ARG 76  81  81  ARG ARG C . n 
C 1 77  VAL 77  82  82  VAL VAL C . n 
C 1 78  PRO 78  83  83  PRO PRO C . n 
C 1 79  GLU 79  83  83  GLU GLU C A n 
C 1 80  TRP 80  84  84  TRP TRP C . n 
C 1 81  SER 81  85  85  SER SER C . n 
C 1 82  TYR 82  86  86  TYR TYR C . n 
C 1 83  ILE 83  87  87  ILE ILE C . n 
C 1 84  VAL 84  88  88  VAL VAL C . n 
C 1 85  GLU 85  89  89  GLU GLU C . n 
C 1 86  ARG 86  90  90  ARG ARG C . n 
C 1 87  ALA 87  91  91  ALA ALA C . n 
C 1 88  ASN 88  92  92  ASN ASN C . n 
C 1 89  PRO 89  93  93  PRO PRO C . n 
C 1 90  ALA 90  94  94  ALA ALA C . n 
C 1 91  ASN 91  95  95  ASN ASN C . n 
C 1 92  ASP 92  96  96  ASP ASP C . n 
C 1 93  LEU 93  96  96  LEU LEU C A n 
C 1 94  CYS 94  97  97  CYS CYS C . n 
C 1 95  TYR 95  98  98  TYR TYR C . n 
C 1 96  PRO 96  99  99  PRO PRO C . n 
C 1 97  GLY 97  100 100 GLY GLY C . n 
C 1 98  SER 98  101 101 SER SER C . n 
C 1 99  LEU 99  102 102 LEU LEU C . n 
C 1 100 ASN 100 103 103 ASN ASN C . n 
C 1 101 ASP 101 104 104 ASP ASP C . n 
C 1 102 TYR 102 105 105 TYR TYR C . n 
C 1 103 GLU 103 106 106 GLU GLU C . n 
C 1 104 GLU 104 107 107 GLU GLU C . n 
C 1 105 LEU 105 108 108 LEU LEU C . n 
C 1 106 LYS 106 109 109 LYS LYS C . n 
C 1 107 HIS 107 110 110 HIS HIS C . n 
C 1 108 MET 108 111 111 MET MET C . n 
C 1 109 LEU 109 112 112 LEU LEU C . n 
C 1 110 SER 110 113 113 SER SER C . n 
C 1 111 ARG 111 114 114 ARG ARG C . n 
C 1 112 ILE 112 115 115 ILE ILE C . n 
C 1 113 ASN 113 116 116 ASN ASN C . n 
C 1 114 HIS 114 117 117 HIS HIS C . n 
C 1 115 PHE 115 118 118 PHE PHE C . n 
C 1 116 GLU 116 119 119 GLU GLU C . n 
C 1 117 LYS 117 120 120 LYS LYS C . n 
C 1 118 ILE 118 121 121 ILE ILE C . n 
C 1 119 GLN 119 122 122 GLN GLN C . n 
C 1 120 ILE 120 123 123 ILE ILE C . n 
C 1 121 ILE 121 124 124 ILE ILE C . n 
C 1 122 PRO 122 125 125 PRO PRO C . n 
C 1 123 LYS 123 125 125 LYS LYS C A n 
C 1 124 SER 124 125 125 SER SER C B n 
C 1 125 SER 125 126 126 SER SER C . n 
C 1 126 TRP 126 127 127 TRP TRP C . n 
C 1 127 PRO 127 128 128 PRO PRO C . n 
C 1 128 ASN 128 129 129 ASN ASN C . n 
C 1 129 HIS 129 130 130 HIS HIS C . n 
C 1 130 GLU 130 131 131 GLU GLU C . n 
C 1 131 THR 131 132 132 THR THR C . n 
C 1 132 SER 132 133 133 SER SER C . n 
C 1 133 LEU 133 133 133 LEU LEU C A n 
C 1 134 GLY 134 134 134 GLY GLY C . n 
C 1 135 VAL 135 135 135 VAL VAL C . n 
C 1 136 SER 136 136 136 SER SER C . n 
C 1 137 ALA 137 137 137 ALA ALA C . n 
C 1 138 ALA 138 138 138 ALA ALA C . n 
C 1 139 CYS 139 139 139 CYS CYS C . n 
C 1 140 PRO 140 140 140 PRO PRO C . n 
C 1 141 TYR 141 141 141 TYR TYR C . n 
C 1 142 GLN 142 142 142 GLN GLN C . n 
C 1 143 GLY 143 143 143 GLY GLY C . n 
C 1 144 ALA 144 144 144 ALA ALA C . n 
C 1 145 PRO 145 145 145 PRO PRO C . n 
C 1 146 SER 146 146 146 SER SER C . n 
C 1 147 PHE 147 147 147 PHE PHE C . n 
C 1 148 PHE 148 148 148 PHE PHE C . n 
C 1 149 ARG 149 149 149 ARG ARG C . n 
C 1 150 ASN 150 150 150 ASN ASN C . n 
C 1 151 VAL 151 151 151 VAL VAL C . n 
C 1 152 VAL 152 152 152 VAL VAL C . n 
C 1 153 TRP 153 153 153 TRP TRP C . n 
C 1 154 LEU 154 154 154 LEU LEU C . n 
C 1 155 ILE 155 155 155 ILE ILE C . n 
C 1 156 LYS 156 156 156 LYS LYS C . n 
C 1 157 LYS 157 157 157 LYS LYS C . n 
C 1 158 ASN 158 158 158 ASN ASN C . n 
C 1 159 ASP 159 159 159 ASP ASP C . n 
C 1 160 ALA 160 160 160 ALA ALA C . n 
C 1 161 TYR 161 161 161 TYR TYR C . n 
C 1 162 PRO 162 162 162 PRO PRO C . n 
C 1 163 THR 163 163 163 THR THR C . n 
C 1 164 ILE 164 164 164 ILE ILE C . n 
C 1 165 LYS 165 165 165 LYS LYS C . n 
C 1 166 ILE 166 166 166 ILE ILE C . n 
C 1 167 SER 167 167 167 SER SER C . n 
C 1 168 TYR 168 168 168 TYR TYR C . n 
C 1 169 ASN 169 169 169 ASN ASN C . n 
C 1 170 ASN 170 170 170 ASN ASN C . n 
C 1 171 THR 171 171 171 THR THR C . n 
C 1 172 ASN 172 172 172 ASN ASN C . n 
C 1 173 ARG 173 173 173 ARG ARG C . n 
C 1 174 GLU 174 174 174 GLU GLU C . n 
C 1 175 ASP 175 175 175 ASP ASP C . n 
C 1 176 LEU 176 176 176 LEU LEU C . n 
C 1 177 LEU 177 177 177 LEU LEU C . n 
C 1 178 ILE 178 178 178 ILE ILE C . n 
C 1 179 LEU 179 179 179 LEU LEU C . n 
C 1 180 TRP 180 180 180 TRP TRP C . n 
C 1 181 GLY 181 181 181 GLY GLY C . n 
C 1 182 ILE 182 182 182 ILE ILE C . n 
C 1 183 HIS 183 183 183 HIS HIS C . n 
C 1 184 HIS 184 184 184 HIS HIS C . n 
C 1 185 SER 185 185 185 SER SER C . n 
C 1 186 ASN 186 186 186 ASN ASN C . n 
C 1 187 ASN 187 187 187 ASN ASN C . n 
C 1 188 ALA 188 188 188 ALA ALA C . n 
C 1 189 GLU 189 189 189 GLU GLU C . n 
C 1 190 GLU 190 190 190 GLU GLU C . n 
C 1 191 GLN 191 191 191 GLN GLN C . n 
C 1 192 THR 192 192 192 THR THR C . n 
C 1 193 ASN 193 193 193 ASN ASN C . n 
C 1 194 LEU 194 194 194 LEU LEU C . n 
C 1 195 TYR 195 195 195 TYR TYR C . n 
C 1 196 LYS 196 196 196 LYS LYS C . n 
C 1 197 ASN 197 197 197 ASN ASN C . n 
C 1 198 PRO 198 198 198 PRO PRO C . n 
C 1 199 ILE 199 199 199 ILE ILE C . n 
C 1 200 THR 200 200 200 THR THR C . n 
C 1 201 TYR 201 201 201 TYR TYR C . n 
C 1 202 ILE 202 202 202 ILE ILE C . n 
C 1 203 SER 203 203 203 SER SER C . n 
C 1 204 VAL 204 204 204 VAL VAL C . n 
C 1 205 GLY 205 205 205 GLY GLY C . n 
C 1 206 THR 206 206 206 THR THR C . n 
C 1 207 SER 207 207 207 SER SER C . n 
C 1 208 THR 208 208 208 THR THR C . n 
C 1 209 LEU 209 209 209 LEU LEU C . n 
C 1 210 ASN 210 210 210 ASN ASN C . n 
C 1 211 GLN 211 211 211 GLN GLN C . n 
C 1 212 ARG 212 212 212 ARG ARG C . n 
C 1 213 LEU 213 213 213 LEU LEU C . n 
C 1 214 ALA 214 214 214 ALA ALA C . n 
C 1 215 PRO 215 215 215 PRO PRO C . n 
C 1 216 LYS 216 216 216 LYS LYS C . n 
C 1 217 ILE 217 217 217 ILE ILE C . n 
C 1 218 ALA 218 218 218 ALA ALA C . n 
C 1 219 THR 219 219 219 THR THR C . n 
C 1 220 ARG 220 220 220 ARG ARG C . n 
C 1 221 SER 221 221 221 SER SER C . n 
C 1 222 GLN 222 222 222 GLN GLN C . n 
C 1 223 VAL 223 223 223 VAL VAL C . n 
C 1 224 ASN 224 224 224 ASN ASN C . n 
C 1 225 GLY 225 225 225 GLY GLY C . n 
C 1 226 GLN 226 226 226 GLN GLN C . n 
C 1 227 ARG 227 227 227 ARG ARG C . n 
C 1 228 GLY 228 228 228 GLY GLY C . n 
C 1 229 ARG 229 229 229 ARG ARG C . n 
C 1 230 MET 230 230 230 MET MET C . n 
C 1 231 ASP 231 231 231 ASP ASP C . n 
C 1 232 PHE 232 232 232 PHE PHE C . n 
C 1 233 PHE 233 233 233 PHE PHE C . n 
C 1 234 TRP 234 234 234 TRP TRP C . n 
C 1 235 THR 235 235 235 THR THR C . n 
C 1 236 ILE 236 236 236 ILE ILE C . n 
C 1 237 LEU 237 237 237 LEU LEU C . n 
C 1 238 LYS 238 238 238 LYS LYS C . n 
C 1 239 PRO 239 239 239 PRO PRO C . n 
C 1 240 ASN 240 240 240 ASN ASN C . n 
C 1 241 ASP 241 241 241 ASP ASP C . n 
C 1 242 ALA 242 242 242 ALA ALA C . n 
C 1 243 ILE 243 243 243 ILE ILE C . n 
C 1 244 HIS 244 244 244 HIS HIS C . n 
C 1 245 PHE 245 245 245 PHE PHE C . n 
C 1 246 GLU 246 246 246 GLU GLU C . n 
C 1 247 SER 247 247 247 SER SER C . n 
C 1 248 ASN 248 248 248 ASN ASN C . n 
C 1 249 GLY 249 249 249 GLY GLY C . n 
C 1 250 ASN 250 250 250 ASN ASN C . n 
C 1 251 PHE 251 251 251 PHE PHE C . n 
C 1 252 ILE 252 252 252 ILE ILE C . n 
C 1 253 ALA 253 253 253 ALA ALA C . n 
C 1 254 PRO 254 254 254 PRO PRO C . n 
C 1 255 GLU 255 255 255 GLU GLU C . n 
C 1 256 TYR 256 256 256 TYR TYR C . n 
C 1 257 ALA 257 257 257 ALA ALA C . n 
C 1 258 TYR 258 258 258 TYR TYR C . n 
C 1 259 LYS 259 259 259 LYS LYS C . n 
C 1 260 ILE 260 260 260 ILE ILE C . n 
C 1 261 VAL 261 260 260 VAL VAL C A n 
C 1 262 LYS 262 261 261 LYS LYS C . n 
C 1 263 LYS 263 262 262 LYS LYS C . n 
C 1 264 GLY 264 263 263 GLY GLY C . n 
C 1 265 ASP 265 264 264 ASP ASP C . n 
C 1 266 SER 266 265 265 SER SER C . n 
C 1 267 THR 267 266 266 THR THR C . n 
C 1 268 ILE 268 267 267 ILE ILE C . n 
C 1 269 MET 269 268 268 MET MET C . n 
C 1 270 LYS 270 269 269 LYS LYS C . n 
C 1 271 SER 271 270 270 SER SER C . n 
C 1 272 GLY 272 271 271 GLY GLY C . n 
C 1 273 VAL 273 272 272 VAL VAL C . n 
C 1 274 GLU 274 273 273 GLU GLU C . n 
C 1 275 TYR 275 274 274 TYR TYR C . n 
C 1 276 GLY 276 275 275 GLY GLY C . n 
C 1 277 HIS 277 276 276 HIS HIS C . n 
C 1 278 CYS 278 277 277 CYS CYS C . n 
C 1 279 ASN 279 278 278 ASN ASN C . n 
C 1 280 THR 280 279 279 THR THR C . n 
C 1 281 LYS 281 280 280 LYS LYS C . n 
C 1 282 CYS 282 281 281 CYS CYS C . n 
C 1 283 GLN 283 282 282 GLN GLN C . n 
C 1 284 THR 284 283 283 THR THR C . n 
C 1 285 PRO 285 284 284 PRO PRO C . n 
C 1 286 VAL 286 285 285 VAL VAL C . n 
C 1 287 GLY 287 286 286 GLY GLY C . n 
C 1 288 ALA 288 287 287 ALA ALA C . n 
C 1 289 ILE 289 288 288 ILE ILE C . n 
C 1 290 ASN 290 289 289 ASN ASN C . n 
C 1 291 SER 291 290 290 SER SER C . n 
C 1 292 SER 292 291 291 SER SER C . n 
C 1 293 MET 293 292 292 MET MET C . n 
C 1 294 PRO 294 293 293 PRO PRO C . n 
C 1 295 PHE 295 294 294 PHE PHE C . n 
C 1 296 HIS 296 295 295 HIS HIS C . n 
C 1 297 ASN 297 296 296 ASN ASN C . n 
C 1 298 ILE 298 297 297 ILE ILE C . n 
C 1 299 HIS 299 298 298 HIS HIS C . n 
C 1 300 PRO 300 299 299 PRO PRO C . n 
C 1 301 LEU 301 300 300 LEU LEU C . n 
C 1 302 THR 302 301 301 THR THR C . n 
C 1 303 ILE 303 302 302 ILE ILE C . n 
C 1 304 GLY 304 303 303 GLY GLY C . n 
C 1 305 GLU 305 304 304 GLU GLU C . n 
C 1 306 CYS 306 305 305 CYS CYS C . n 
C 1 307 PRO 307 306 306 PRO PRO C . n 
C 1 308 LYS 308 307 307 LYS LYS C . n 
C 1 309 TYR 309 308 308 TYR TYR C . n 
C 1 310 VAL 310 309 309 VAL VAL C . n 
C 1 311 LYS 311 310 310 LYS LYS C . n 
C 1 312 SER 312 311 311 SER SER C . n 
C 1 313 ASN 313 312 312 ASN ASN C . n 
C 1 314 LYS 314 313 313 LYS LYS C . n 
C 1 315 LEU 315 314 314 LEU LEU C . n 
C 1 316 VAL 316 315 315 VAL VAL C . n 
C 1 317 LEU 317 316 316 LEU LEU C . n 
C 1 318 ALA 318 317 317 ALA ALA C . n 
C 1 319 THR 319 318 318 THR THR C . n 
C 1 320 GLY 320 319 319 GLY GLY C . n 
C 1 321 LEU 321 320 320 LEU LEU C . n 
C 1 322 ARG 322 321 321 ARG ARG C . n 
C 1 323 ASN 323 322 322 ASN ASN C . n 
C 1 324 SER 324 323 323 SER SER C . n 
C 1 325 PRO 325 324 324 PRO PRO C . n 
D 2 1   GLY 1   1   1   GLY GLY D . n 
D 2 2   LEU 2   2   2   LEU LEU D . n 
D 2 3   PHE 3   3   3   PHE PHE D . n 
D 2 4   GLY 4   4   4   GLY GLY D . n 
D 2 5   ALA 5   5   5   ALA ALA D . n 
D 2 6   ILE 6   6   6   ILE ILE D . n 
D 2 7   ALA 7   7   7   ALA ALA D . n 
D 2 8   GLY 8   8   8   GLY GLY D . n 
D 2 9   PHE 9   9   9   PHE PHE D . n 
D 2 10  ILE 10  10  10  ILE ILE D . n 
D 2 11  GLU 11  11  11  GLU GLU D . n 
D 2 12  GLY 12  12  12  GLY GLY D . n 
D 2 13  GLY 13  13  13  GLY GLY D . n 
D 2 14  TRP 14  14  14  TRP TRP D . n 
D 2 15  GLN 15  15  15  GLN GLN D . n 
D 2 16  GLY 16  16  16  GLY GLY D . n 
D 2 17  MET 17  17  17  MET MET D . n 
D 2 18  VAL 18  18  18  VAL VAL D . n 
D 2 19  ASP 19  19  19  ASP ASP D . n 
D 2 20  GLY 20  20  20  GLY GLY D . n 
D 2 21  TRP 21  21  21  TRP TRP D . n 
D 2 22  TYR 22  22  22  TYR TYR D . n 
D 2 23  GLY 23  23  23  GLY GLY D . n 
D 2 24  TYR 24  24  24  TYR TYR D . n 
D 2 25  HIS 25  25  25  HIS HIS D . n 
D 2 26  HIS 26  26  26  HIS HIS D . n 
D 2 27  SER 27  27  27  SER SER D . n 
D 2 28  ASN 28  28  28  ASN ASN D . n 
D 2 29  GLU 29  29  29  GLU GLU D . n 
D 2 30  GLN 30  30  30  GLN GLN D . n 
D 2 31  GLY 31  31  31  GLY GLY D . n 
D 2 32  SER 32  32  32  SER SER D . n 
D 2 33  GLY 33  33  33  GLY GLY D . n 
D 2 34  TYR 34  34  34  TYR TYR D . n 
D 2 35  ALA 35  35  35  ALA ALA D . n 
D 2 36  ALA 36  36  36  ALA ALA D . n 
D 2 37  ASP 37  37  37  ASP ASP D . n 
D 2 38  LYS 38  38  38  LYS LYS D . n 
D 2 39  GLU 39  39  39  GLU GLU D . n 
D 2 40  SER 40  40  40  SER SER D . n 
D 2 41  THR 41  41  41  THR THR D . n 
D 2 42  GLN 42  42  42  GLN GLN D . n 
D 2 43  LYS 43  43  43  LYS LYS D . n 
D 2 44  ALA 44  44  44  ALA ALA D . n 
D 2 45  ILE 45  45  45  ILE ILE D . n 
D 2 46  ASP 46  46  46  ASP ASP D . n 
D 2 47  GLY 47  47  47  GLY GLY D . n 
D 2 48  VAL 48  48  48  VAL VAL D . n 
D 2 49  THR 49  49  49  THR THR D . n 
D 2 50  ASN 50  50  50  ASN ASN D . n 
D 2 51  LYS 51  51  51  LYS LYS D . n 
D 2 52  VAL 52  52  52  VAL VAL D . n 
D 2 53  ASN 53  53  53  ASN ASN D . n 
D 2 54  SER 54  54  54  SER SER D . n 
D 2 55  ILE 55  55  55  ILE ILE D . n 
D 2 56  ILE 56  56  56  ILE ILE D . n 
D 2 57  ASP 57  57  57  ASP ASP D . n 
D 2 58  LYS 58  58  58  LYS LYS D . n 
D 2 59  MET 59  59  59  MET MET D . n 
D 2 60  ASN 60  60  60  ASN ASN D . n 
D 2 61  THR 61  61  61  THR THR D . n 
D 2 62  GLN 62  62  62  GLN GLN D . n 
D 2 63  PHE 63  63  63  PHE PHE D . n 
D 2 64  GLU 64  64  64  GLU GLU D . n 
D 2 65  ALA 65  65  65  ALA ALA D . n 
D 2 66  VAL 66  66  66  VAL VAL D . n 
D 2 67  GLY 67  67  67  GLY GLY D . n 
D 2 68  ARG 68  68  68  ARG ARG D . n 
D 2 69  GLU 69  69  69  GLU GLU D . n 
D 2 70  PHE 70  70  70  PHE PHE D . n 
D 2 71  ASN 71  71  71  ASN ASN D . n 
D 2 72  ASN 72  72  72  ASN ASN D . n 
D 2 73  LEU 73  73  73  LEU LEU D . n 
D 2 74  GLU 74  74  74  GLU GLU D . n 
D 2 75  ARG 75  75  75  ARG ARG D . n 
D 2 76  ARG 76  76  76  ARG ARG D . n 
D 2 77  ILE 77  77  77  ILE ILE D . n 
D 2 78  GLU 78  78  78  GLU GLU D . n 
D 2 79  ASN 79  79  79  ASN ASN D . n 
D 2 80  LEU 80  80  80  LEU LEU D . n 
D 2 81  ASN 81  81  81  ASN ASN D . n 
D 2 82  LYS 82  82  82  LYS LYS D . n 
D 2 83  LYS 83  83  83  LYS LYS D . n 
D 2 84  MET 84  84  84  MET MET D . n 
D 2 85  GLU 85  85  85  GLU GLU D . n 
D 2 86  ASP 86  86  86  ASP ASP D . n 
D 2 87  GLY 87  87  87  GLY GLY D . n 
D 2 88  PHE 88  88  88  PHE PHE D . n 
D 2 89  LEU 89  89  89  LEU LEU D . n 
D 2 90  ASP 90  90  90  ASP ASP D . n 
D 2 91  VAL 91  91  91  VAL VAL D . n 
D 2 92  TRP 92  92  92  TRP TRP D . n 
D 2 93  THR 93  93  93  THR THR D . n 
D 2 94  TYR 94  94  94  TYR TYR D . n 
D 2 95  ASN 95  95  95  ASN ASN D . n 
D 2 96  ALA 96  96  96  ALA ALA D . n 
D 2 97  GLU 97  97  97  GLU GLU D . n 
D 2 98  LEU 98  98  98  LEU LEU D . n 
D 2 99  LEU 99  99  99  LEU LEU D . n 
D 2 100 VAL 100 100 100 VAL VAL D . n 
D 2 101 LEU 101 101 101 LEU LEU D . n 
D 2 102 MET 102 102 102 MET MET D . n 
D 2 103 GLU 103 103 103 GLU GLU D . n 
D 2 104 ASN 104 104 104 ASN ASN D . n 
D 2 105 GLU 105 105 105 GLU GLU D . n 
D 2 106 ARG 106 106 106 ARG ARG D . n 
D 2 107 THR 107 107 107 THR THR D . n 
D 2 108 LEU 108 108 108 LEU LEU D . n 
D 2 109 ASP 109 109 109 ASP ASP D . n 
D 2 110 PHE 110 110 110 PHE PHE D . n 
D 2 111 HIS 111 111 111 HIS HIS D . n 
D 2 112 ASP 112 112 112 ASP ASP D . n 
D 2 113 SER 113 113 113 SER SER D . n 
D 2 114 ASN 114 114 114 ASN ASN D . n 
D 2 115 VAL 115 115 115 VAL VAL D . n 
D 2 116 LYS 116 116 116 LYS LYS D . n 
D 2 117 ASN 117 117 117 ASN ASN D . n 
D 2 118 LEU 118 118 118 LEU LEU D . n 
D 2 119 TYR 119 119 119 TYR TYR D . n 
D 2 120 ASP 120 120 120 ASP ASP D . n 
D 2 121 LYS 121 121 121 LYS LYS D . n 
D 2 122 VAL 122 122 122 VAL VAL D . n 
D 2 123 ARG 123 123 123 ARG ARG D . n 
D 2 124 LEU 124 124 124 LEU LEU D . n 
D 2 125 GLN 125 125 125 GLN GLN D . n 
D 2 126 LEU 126 126 126 LEU LEU D . n 
D 2 127 ARG 127 127 127 ARG ARG D . n 
D 2 128 ASP 128 128 128 ASP ASP D . n 
D 2 129 ASN 129 129 129 ASN ASN D . n 
D 2 130 ALA 130 130 130 ALA ALA D . n 
D 2 131 LYS 131 131 131 LYS LYS D . n 
D 2 132 GLU 132 132 132 GLU GLU D . n 
D 2 133 LEU 133 133 133 LEU LEU D . n 
D 2 134 GLY 134 134 134 GLY GLY D . n 
D 2 135 ASN 135 135 135 ASN ASN D . n 
D 2 136 GLY 136 136 136 GLY GLY D . n 
D 2 137 CYS 137 137 137 CYS CYS D . n 
D 2 138 PHE 138 138 138 PHE PHE D . n 
D 2 139 GLU 139 139 139 GLU GLU D . n 
D 2 140 PHE 140 140 140 PHE PHE D . n 
D 2 141 TYR 141 141 141 TYR TYR D . n 
D 2 142 HIS 142 142 142 HIS HIS D . n 
D 2 143 LYS 143 143 143 LYS LYS D . n 
D 2 144 CYS 144 144 144 CYS CYS D . n 
D 2 145 ASP 145 145 145 ASP ASP D . n 
D 2 146 ASN 146 146 146 ASN ASN D . n 
D 2 147 GLU 147 147 147 GLU GLU D . n 
D 2 148 CYS 148 148 148 CYS CYS D . n 
D 2 149 MET 149 149 149 MET MET D . n 
D 2 150 GLU 150 150 150 GLU GLU D . n 
D 2 151 SER 151 151 151 SER SER D . n 
D 2 152 VAL 152 152 152 VAL VAL D . n 
D 2 153 ARG 153 153 153 ARG ARG D . n 
D 2 154 ASN 154 154 154 ASN ASN D . n 
D 2 155 GLY 155 155 155 GLY GLY D . n 
D 2 156 THR 156 156 156 THR THR D . n 
D 2 157 TYR 157 157 157 TYR TYR D . n 
D 2 158 ASP 158 158 158 ASP ASP D . n 
D 2 159 TYR 159 159 159 TYR TYR D . n 
D 2 160 PRO 160 160 160 PRO PRO D . n 
D 2 161 GLN 161 161 161 GLN GLN D . n 
D 2 162 TYR 162 162 162 TYR TYR D . n 
D 2 163 SER 163 163 163 SER SER D . n 
D 2 164 GLU 164 164 164 GLU GLU D . n 
D 2 165 GLU 165 165 165 GLU GLU D . n 
D 2 166 ALA 166 166 166 ALA ALA D . n 
D 2 167 ARG 167 167 167 ARG ARG D . n 
D 2 168 LEU 168 168 168 LEU LEU D . n 
D 2 169 LYS 169 169 169 LYS LYS D . n 
D 2 170 ARG 170 170 170 ARG ARG D . n 
D 2 171 GLU 171 171 171 GLU GLU D . n 
D 2 172 GLU 172 172 172 GLU GLU D . n 
D 2 173 ILE 173 173 173 ILE ILE D . n 
D 2 174 SER 174 174 174 SER SER D . n 
D 2 175 SER 175 175 ?   ?   ?   D . n 
D 2 176 GLY 176 176 ?   ?   ?   D . n 
E 1 1   ALA 1   7   ?   ?   ?   I . n 
E 1 2   ASP 2   8   ?   ?   ?   I . n 
E 1 3   PRO 3   9   ?   ?   ?   I . n 
E 1 4   GLY 4   10  10  GLY GLY I . n 
E 1 5   ASP 5   11  11  ASP ASP I . n 
E 1 6   GLN 6   12  12  GLN GLN I . n 
E 1 7   ILE 7   13  13  ILE ILE I . n 
E 1 8   CYS 8   14  14  CYS CYS I . n 
E 1 9   ILE 9   15  15  ILE ILE I . n 
E 1 10  GLY 10  16  16  GLY GLY I . n 
E 1 11  TYR 11  17  17  TYR TYR I . n 
E 1 12  HIS 12  18  18  HIS HIS I . n 
E 1 13  ALA 13  19  19  ALA ALA I . n 
E 1 14  ASN 14  20  20  ASN ASN I . n 
E 1 15  ASN 15  21  21  ASN ASN I . n 
E 1 16  SER 16  22  22  SER SER I . n 
E 1 17  THR 17  23  23  THR THR I . n 
E 1 18  GLU 18  24  24  GLU GLU I . n 
E 1 19  GLN 19  25  25  GLN GLN I . n 
E 1 20  VAL 20  26  26  VAL VAL I . n 
E 1 21  ASP 21  27  27  ASP ASP I . n 
E 1 22  THR 22  28  28  THR THR I . n 
E 1 23  ILE 23  29  29  ILE ILE I . n 
E 1 24  MET 24  30  30  MET MET I . n 
E 1 25  GLU 25  31  31  GLU GLU I . n 
E 1 26  LYS 26  32  32  LYS LYS I . n 
E 1 27  ASN 27  33  33  ASN ASN I . n 
E 1 28  VAL 28  34  34  VAL VAL I . n 
E 1 29  THR 29  35  35  THR THR I . n 
E 1 30  VAL 30  36  36  VAL VAL I . n 
E 1 31  THR 31  37  37  THR THR I . n 
E 1 32  HIS 32  38  38  HIS HIS I . n 
E 1 33  ALA 33  39  39  ALA ALA I . n 
E 1 34  GLN 34  40  40  GLN GLN I . n 
E 1 35  ASP 35  41  41  ASP ASP I . n 
E 1 36  ILE 36  42  42  ILE ILE I . n 
E 1 37  LEU 37  43  43  LEU LEU I . n 
E 1 38  GLU 38  44  44  GLU GLU I . n 
E 1 39  LYS 39  45  45  LYS LYS I . n 
E 1 40  THR 40  46  46  THR THR I . n 
E 1 41  HIS 41  47  47  HIS HIS I . n 
E 1 42  ASN 42  48  48  ASN ASN I . n 
E 1 43  GLY 43  49  49  GLY GLY I . n 
E 1 44  LYS 44  50  50  LYS LYS I . n 
E 1 45  LEU 45  51  51  LEU LEU I . n 
E 1 46  CYS 46  52  52  CYS CYS I . n 
E 1 47  ASP 47  53  53  ASP ASP I . n 
E 1 48  LEU 48  54  54  LEU LEU I . n 
E 1 49  ASN 49  55  55  ASN ASN I . n 
E 1 50  GLY 50  55  55  GLY GLY I A n 
E 1 51  VAL 51  56  56  VAL VAL I . n 
E 1 52  LYS 52  57  57  LYS LYS I . n 
E 1 53  PRO 53  58  58  PRO PRO I . n 
E 1 54  LEU 54  59  59  LEU LEU I . n 
E 1 55  ILE 55  60  60  ILE ILE I . n 
E 1 56  LEU 56  61  61  LEU LEU I . n 
E 1 57  LYS 57  62  62  LYS LYS I . n 
E 1 58  ASP 58  63  63  ASP ASP I . n 
E 1 59  CYS 59  64  64  CYS CYS I . n 
E 1 60  SER 60  65  65  SER SER I . n 
E 1 61  VAL 61  66  66  VAL VAL I . n 
E 1 62  ALA 62  67  67  ALA ALA I . n 
E 1 63  GLY 63  68  68  GLY GLY I . n 
E 1 64  TRP 64  69  69  TRP TRP I . n 
E 1 65  LEU 65  70  70  LEU LEU I . n 
E 1 66  LEU 66  71  71  LEU LEU I . n 
E 1 67  GLY 67  72  72  GLY GLY I . n 
E 1 68  ASN 68  73  73  ASN ASN I . n 
E 1 69  PRO 69  74  74  PRO PRO I . n 
E 1 70  MET 70  75  75  MET MET I . n 
E 1 71  CYS 71  76  76  CYS CYS I . n 
E 1 72  ASP 72  77  77  ASP ASP I . n 
E 1 73  GLU 73  78  78  GLU GLU I . n 
E 1 74  PHE 74  79  79  PHE PHE I . n 
E 1 75  ILE 75  80  80  ILE ILE I . n 
E 1 76  ARG 76  81  81  ARG ARG I . n 
E 1 77  VAL 77  82  82  VAL VAL I . n 
E 1 78  PRO 78  83  83  PRO PRO I . n 
E 1 79  GLU 79  83  83  GLU GLU I A n 
E 1 80  TRP 80  84  84  TRP TRP I . n 
E 1 81  SER 81  85  85  SER SER I . n 
E 1 82  TYR 82  86  86  TYR TYR I . n 
E 1 83  ILE 83  87  87  ILE ILE I . n 
E 1 84  VAL 84  88  88  VAL VAL I . n 
E 1 85  GLU 85  89  89  GLU GLU I . n 
E 1 86  ARG 86  90  90  ARG ARG I . n 
E 1 87  ALA 87  91  91  ALA ALA I . n 
E 1 88  ASN 88  92  92  ASN ASN I . n 
E 1 89  PRO 89  93  93  PRO PRO I . n 
E 1 90  ALA 90  94  94  ALA ALA I . n 
E 1 91  ASN 91  95  95  ASN ASN I . n 
E 1 92  ASP 92  96  96  ASP ASP I . n 
E 1 93  LEU 93  96  96  LEU LEU I A n 
E 1 94  CYS 94  97  97  CYS CYS I . n 
E 1 95  TYR 95  98  98  TYR TYR I . n 
E 1 96  PRO 96  99  99  PRO PRO I . n 
E 1 97  GLY 97  100 100 GLY GLY I . n 
E 1 98  SER 98  101 101 SER SER I . n 
E 1 99  LEU 99  102 102 LEU LEU I . n 
E 1 100 ASN 100 103 103 ASN ASN I . n 
E 1 101 ASP 101 104 104 ASP ASP I . n 
E 1 102 TYR 102 105 105 TYR TYR I . n 
E 1 103 GLU 103 106 106 GLU GLU I . n 
E 1 104 GLU 104 107 107 GLU GLU I . n 
E 1 105 LEU 105 108 108 LEU LEU I . n 
E 1 106 LYS 106 109 109 LYS LYS I . n 
E 1 107 HIS 107 110 110 HIS HIS I . n 
E 1 108 MET 108 111 111 MET MET I . n 
E 1 109 LEU 109 112 112 LEU LEU I . n 
E 1 110 SER 110 113 113 SER SER I . n 
E 1 111 ARG 111 114 114 ARG ARG I . n 
E 1 112 ILE 112 115 115 ILE ILE I . n 
E 1 113 ASN 113 116 116 ASN ASN I . n 
E 1 114 HIS 114 117 117 HIS HIS I . n 
E 1 115 PHE 115 118 118 PHE PHE I . n 
E 1 116 GLU 116 119 119 GLU GLU I . n 
E 1 117 LYS 117 120 120 LYS LYS I . n 
E 1 118 ILE 118 121 121 ILE ILE I . n 
E 1 119 GLN 119 122 122 GLN GLN I . n 
E 1 120 ILE 120 123 123 ILE ILE I . n 
E 1 121 ILE 121 124 124 ILE ILE I . n 
E 1 122 PRO 122 125 125 PRO PRO I . n 
E 1 123 LYS 123 125 125 LYS LYS I A n 
E 1 124 SER 124 125 125 SER SER I B n 
E 1 125 SER 125 126 126 SER SER I . n 
E 1 126 TRP 126 127 127 TRP TRP I . n 
E 1 127 PRO 127 128 128 PRO PRO I . n 
E 1 128 ASN 128 129 129 ASN ASN I . n 
E 1 129 HIS 129 130 130 HIS HIS I . n 
E 1 130 GLU 130 131 131 GLU GLU I . n 
E 1 131 THR 131 132 132 THR THR I . n 
E 1 132 SER 132 133 133 SER SER I . n 
E 1 133 LEU 133 133 133 LEU LEU I A n 
E 1 134 GLY 134 134 134 GLY GLY I . n 
E 1 135 VAL 135 135 135 VAL VAL I . n 
E 1 136 SER 136 136 136 SER SER I . n 
E 1 137 ALA 137 137 137 ALA ALA I . n 
E 1 138 ALA 138 138 138 ALA ALA I . n 
E 1 139 CYS 139 139 139 CYS CYS I . n 
E 1 140 PRO 140 140 140 PRO PRO I . n 
E 1 141 TYR 141 141 141 TYR TYR I . n 
E 1 142 GLN 142 142 142 GLN GLN I . n 
E 1 143 GLY 143 143 143 GLY GLY I . n 
E 1 144 ALA 144 144 144 ALA ALA I . n 
E 1 145 PRO 145 145 145 PRO PRO I . n 
E 1 146 SER 146 146 146 SER SER I . n 
E 1 147 PHE 147 147 147 PHE PHE I . n 
E 1 148 PHE 148 148 148 PHE PHE I . n 
E 1 149 ARG 149 149 149 ARG ARG I . n 
E 1 150 ASN 150 150 150 ASN ASN I . n 
E 1 151 VAL 151 151 151 VAL VAL I . n 
E 1 152 VAL 152 152 152 VAL VAL I . n 
E 1 153 TRP 153 153 153 TRP TRP I . n 
E 1 154 LEU 154 154 154 LEU LEU I . n 
E 1 155 ILE 155 155 155 ILE ILE I . n 
E 1 156 LYS 156 156 156 LYS LYS I . n 
E 1 157 LYS 157 157 157 LYS LYS I . n 
E 1 158 ASN 158 158 158 ASN ASN I . n 
E 1 159 ASP 159 159 159 ASP ASP I . n 
E 1 160 ALA 160 160 160 ALA ALA I . n 
E 1 161 TYR 161 161 161 TYR TYR I . n 
E 1 162 PRO 162 162 162 PRO PRO I . n 
E 1 163 THR 163 163 163 THR THR I . n 
E 1 164 ILE 164 164 164 ILE ILE I . n 
E 1 165 LYS 165 165 165 LYS LYS I . n 
E 1 166 ILE 166 166 166 ILE ILE I . n 
E 1 167 SER 167 167 167 SER SER I . n 
E 1 168 TYR 168 168 168 TYR TYR I . n 
E 1 169 ASN 169 169 169 ASN ASN I . n 
E 1 170 ASN 170 170 170 ASN ASN I . n 
E 1 171 THR 171 171 171 THR THR I . n 
E 1 172 ASN 172 172 172 ASN ASN I . n 
E 1 173 ARG 173 173 173 ARG ARG I . n 
E 1 174 GLU 174 174 174 GLU GLU I . n 
E 1 175 ASP 175 175 175 ASP ASP I . n 
E 1 176 LEU 176 176 176 LEU LEU I . n 
E 1 177 LEU 177 177 177 LEU LEU I . n 
E 1 178 ILE 178 178 178 ILE ILE I . n 
E 1 179 LEU 179 179 179 LEU LEU I . n 
E 1 180 TRP 180 180 180 TRP TRP I . n 
E 1 181 GLY 181 181 181 GLY GLY I . n 
E 1 182 ILE 182 182 182 ILE ILE I . n 
E 1 183 HIS 183 183 183 HIS HIS I . n 
E 1 184 HIS 184 184 184 HIS HIS I . n 
E 1 185 SER 185 185 185 SER SER I . n 
E 1 186 ASN 186 186 186 ASN ASN I . n 
E 1 187 ASN 187 187 187 ASN ASN I . n 
E 1 188 ALA 188 188 188 ALA ALA I . n 
E 1 189 GLU 189 189 189 GLU GLU I . n 
E 1 190 GLU 190 190 190 GLU GLU I . n 
E 1 191 GLN 191 191 191 GLN GLN I . n 
E 1 192 THR 192 192 192 THR THR I . n 
E 1 193 ASN 193 193 193 ASN ASN I . n 
E 1 194 LEU 194 194 194 LEU LEU I . n 
E 1 195 TYR 195 195 195 TYR TYR I . n 
E 1 196 LYS 196 196 196 LYS LYS I . n 
E 1 197 ASN 197 197 197 ASN ASN I . n 
E 1 198 PRO 198 198 198 PRO PRO I . n 
E 1 199 ILE 199 199 199 ILE ILE I . n 
E 1 200 THR 200 200 200 THR THR I . n 
E 1 201 TYR 201 201 201 TYR TYR I . n 
E 1 202 ILE 202 202 202 ILE ILE I . n 
E 1 203 SER 203 203 203 SER SER I . n 
E 1 204 VAL 204 204 204 VAL VAL I . n 
E 1 205 GLY 205 205 205 GLY GLY I . n 
E 1 206 THR 206 206 206 THR THR I . n 
E 1 207 SER 207 207 207 SER SER I . n 
E 1 208 THR 208 208 208 THR THR I . n 
E 1 209 LEU 209 209 209 LEU LEU I . n 
E 1 210 ASN 210 210 210 ASN ASN I . n 
E 1 211 GLN 211 211 211 GLN GLN I . n 
E 1 212 ARG 212 212 212 ARG ARG I . n 
E 1 213 LEU 213 213 213 LEU LEU I . n 
E 1 214 ALA 214 214 214 ALA ALA I . n 
E 1 215 PRO 215 215 215 PRO PRO I . n 
E 1 216 LYS 216 216 216 LYS LYS I . n 
E 1 217 ILE 217 217 217 ILE ILE I . n 
E 1 218 ALA 218 218 218 ALA ALA I . n 
E 1 219 THR 219 219 219 THR THR I . n 
E 1 220 ARG 220 220 220 ARG ARG I . n 
E 1 221 SER 221 221 221 SER SER I . n 
E 1 222 GLN 222 222 222 GLN GLN I . n 
E 1 223 VAL 223 223 223 VAL VAL I . n 
E 1 224 ASN 224 224 224 ASN ASN I . n 
E 1 225 GLY 225 225 225 GLY GLY I . n 
E 1 226 GLN 226 226 226 GLN GLN I . n 
E 1 227 ARG 227 227 227 ARG ARG I . n 
E 1 228 GLY 228 228 228 GLY GLY I . n 
E 1 229 ARG 229 229 229 ARG ARG I . n 
E 1 230 MET 230 230 230 MET MET I . n 
E 1 231 ASP 231 231 231 ASP ASP I . n 
E 1 232 PHE 232 232 232 PHE PHE I . n 
E 1 233 PHE 233 233 233 PHE PHE I . n 
E 1 234 TRP 234 234 234 TRP TRP I . n 
E 1 235 THR 235 235 235 THR THR I . n 
E 1 236 ILE 236 236 236 ILE ILE I . n 
E 1 237 LEU 237 237 237 LEU LEU I . n 
E 1 238 LYS 238 238 238 LYS LYS I . n 
E 1 239 PRO 239 239 239 PRO PRO I . n 
E 1 240 ASN 240 240 240 ASN ASN I . n 
E 1 241 ASP 241 241 241 ASP ASP I . n 
E 1 242 ALA 242 242 242 ALA ALA I . n 
E 1 243 ILE 243 243 243 ILE ILE I . n 
E 1 244 HIS 244 244 244 HIS HIS I . n 
E 1 245 PHE 245 245 245 PHE PHE I . n 
E 1 246 GLU 246 246 246 GLU GLU I . n 
E 1 247 SER 247 247 247 SER SER I . n 
E 1 248 ASN 248 248 248 ASN ASN I . n 
E 1 249 GLY 249 249 249 GLY GLY I . n 
E 1 250 ASN 250 250 250 ASN ASN I . n 
E 1 251 PHE 251 251 251 PHE PHE I . n 
E 1 252 ILE 252 252 252 ILE ILE I . n 
E 1 253 ALA 253 253 253 ALA ALA I . n 
E 1 254 PRO 254 254 254 PRO PRO I . n 
E 1 255 GLU 255 255 255 GLU GLU I . n 
E 1 256 TYR 256 256 256 TYR TYR I . n 
E 1 257 ALA 257 257 257 ALA ALA I . n 
E 1 258 TYR 258 258 258 TYR TYR I . n 
E 1 259 LYS 259 259 259 LYS LYS I . n 
E 1 260 ILE 260 260 260 ILE ILE I . n 
E 1 261 VAL 261 260 260 VAL VAL I A n 
E 1 262 LYS 262 261 261 LYS LYS I . n 
E 1 263 LYS 263 262 262 LYS LYS I . n 
E 1 264 GLY 264 263 263 GLY GLY I . n 
E 1 265 ASP 265 264 264 ASP ASP I . n 
E 1 266 SER 266 265 265 SER SER I . n 
E 1 267 THR 267 266 266 THR THR I . n 
E 1 268 ILE 268 267 267 ILE ILE I . n 
E 1 269 MET 269 268 268 MET MET I . n 
E 1 270 LYS 270 269 269 LYS LYS I . n 
E 1 271 SER 271 270 270 SER SER I . n 
E 1 272 GLY 272 271 271 GLY GLY I . n 
E 1 273 VAL 273 272 272 VAL VAL I . n 
E 1 274 GLU 274 273 273 GLU GLU I . n 
E 1 275 TYR 275 274 274 TYR TYR I . n 
E 1 276 GLY 276 275 275 GLY GLY I . n 
E 1 277 HIS 277 276 276 HIS HIS I . n 
E 1 278 CYS 278 277 277 CYS CYS I . n 
E 1 279 ASN 279 278 278 ASN ASN I . n 
E 1 280 THR 280 279 279 THR THR I . n 
E 1 281 LYS 281 280 280 LYS LYS I . n 
E 1 282 CYS 282 281 281 CYS CYS I . n 
E 1 283 GLN 283 282 282 GLN GLN I . n 
E 1 284 THR 284 283 283 THR THR I . n 
E 1 285 PRO 285 284 284 PRO PRO I . n 
E 1 286 VAL 286 285 285 VAL VAL I . n 
E 1 287 GLY 287 286 286 GLY GLY I . n 
E 1 288 ALA 288 287 287 ALA ALA I . n 
E 1 289 ILE 289 288 288 ILE ILE I . n 
E 1 290 ASN 290 289 289 ASN ASN I . n 
E 1 291 SER 291 290 290 SER SER I . n 
E 1 292 SER 292 291 291 SER SER I . n 
E 1 293 MET 293 292 292 MET MET I . n 
E 1 294 PRO 294 293 293 PRO PRO I . n 
E 1 295 PHE 295 294 294 PHE PHE I . n 
E 1 296 HIS 296 295 295 HIS HIS I . n 
E 1 297 ASN 297 296 296 ASN ASN I . n 
E 1 298 ILE 298 297 297 ILE ILE I . n 
E 1 299 HIS 299 298 298 HIS HIS I . n 
E 1 300 PRO 300 299 299 PRO PRO I . n 
E 1 301 LEU 301 300 300 LEU LEU I . n 
E 1 302 THR 302 301 301 THR THR I . n 
E 1 303 ILE 303 302 302 ILE ILE I . n 
E 1 304 GLY 304 303 303 GLY GLY I . n 
E 1 305 GLU 305 304 304 GLU GLU I . n 
E 1 306 CYS 306 305 305 CYS CYS I . n 
E 1 307 PRO 307 306 306 PRO PRO I . n 
E 1 308 LYS 308 307 307 LYS LYS I . n 
E 1 309 TYR 309 308 308 TYR TYR I . n 
E 1 310 VAL 310 309 309 VAL VAL I . n 
E 1 311 LYS 311 310 310 LYS LYS I . n 
E 1 312 SER 312 311 311 SER SER I . n 
E 1 313 ASN 313 312 312 ASN ASN I . n 
E 1 314 LYS 314 313 313 LYS LYS I . n 
E 1 315 LEU 315 314 314 LEU LEU I . n 
E 1 316 VAL 316 315 315 VAL VAL I . n 
E 1 317 LEU 317 316 316 LEU LEU I . n 
E 1 318 ALA 318 317 317 ALA ALA I . n 
E 1 319 THR 319 318 318 THR THR I . n 
E 1 320 GLY 320 319 319 GLY GLY I . n 
E 1 321 LEU 321 320 320 LEU LEU I . n 
E 1 322 ARG 322 321 321 ARG ARG I . n 
E 1 323 ASN 323 322 322 ASN ASN I . n 
E 1 324 SER 324 323 323 SER SER I . n 
E 1 325 PRO 325 324 324 PRO PRO I . n 
F 2 1   GLY 1   1   1   GLY GLY J . n 
F 2 2   LEU 2   2   2   LEU LEU J . n 
F 2 3   PHE 3   3   3   PHE PHE J . n 
F 2 4   GLY 4   4   4   GLY GLY J . n 
F 2 5   ALA 5   5   5   ALA ALA J . n 
F 2 6   ILE 6   6   6   ILE ILE J . n 
F 2 7   ALA 7   7   7   ALA ALA J . n 
F 2 8   GLY 8   8   8   GLY GLY J . n 
F 2 9   PHE 9   9   9   PHE PHE J . n 
F 2 10  ILE 10  10  10  ILE ILE J . n 
F 2 11  GLU 11  11  11  GLU GLU J . n 
F 2 12  GLY 12  12  12  GLY GLY J . n 
F 2 13  GLY 13  13  13  GLY GLY J . n 
F 2 14  TRP 14  14  14  TRP TRP J . n 
F 2 15  GLN 15  15  15  GLN GLN J . n 
F 2 16  GLY 16  16  16  GLY GLY J . n 
F 2 17  MET 17  17  17  MET MET J . n 
F 2 18  VAL 18  18  18  VAL VAL J . n 
F 2 19  ASP 19  19  19  ASP ASP J . n 
F 2 20  GLY 20  20  20  GLY GLY J . n 
F 2 21  TRP 21  21  21  TRP TRP J . n 
F 2 22  TYR 22  22  22  TYR TYR J . n 
F 2 23  GLY 23  23  23  GLY GLY J . n 
F 2 24  TYR 24  24  24  TYR TYR J . n 
F 2 25  HIS 25  25  25  HIS HIS J . n 
F 2 26  HIS 26  26  26  HIS HIS J . n 
F 2 27  SER 27  27  27  SER SER J . n 
F 2 28  ASN 28  28  28  ASN ASN J . n 
F 2 29  GLU 29  29  29  GLU GLU J . n 
F 2 30  GLN 30  30  30  GLN GLN J . n 
F 2 31  GLY 31  31  31  GLY GLY J . n 
F 2 32  SER 32  32  32  SER SER J . n 
F 2 33  GLY 33  33  33  GLY GLY J . n 
F 2 34  TYR 34  34  34  TYR TYR J . n 
F 2 35  ALA 35  35  35  ALA ALA J . n 
F 2 36  ALA 36  36  36  ALA ALA J . n 
F 2 37  ASP 37  37  37  ASP ASP J . n 
F 2 38  LYS 38  38  38  LYS LYS J . n 
F 2 39  GLU 39  39  39  GLU GLU J . n 
F 2 40  SER 40  40  40  SER SER J . n 
F 2 41  THR 41  41  41  THR THR J . n 
F 2 42  GLN 42  42  42  GLN GLN J . n 
F 2 43  LYS 43  43  43  LYS LYS J . n 
F 2 44  ALA 44  44  44  ALA ALA J . n 
F 2 45  ILE 45  45  45  ILE ILE J . n 
F 2 46  ASP 46  46  46  ASP ASP J . n 
F 2 47  GLY 47  47  47  GLY GLY J . n 
F 2 48  VAL 48  48  48  VAL VAL J . n 
F 2 49  THR 49  49  49  THR THR J . n 
F 2 50  ASN 50  50  50  ASN ASN J . n 
F 2 51  LYS 51  51  51  LYS LYS J . n 
F 2 52  VAL 52  52  52  VAL VAL J . n 
F 2 53  ASN 53  53  53  ASN ASN J . n 
F 2 54  SER 54  54  54  SER SER J . n 
F 2 55  ILE 55  55  55  ILE ILE J . n 
F 2 56  ILE 56  56  56  ILE ILE J . n 
F 2 57  ASP 57  57  57  ASP ASP J . n 
F 2 58  LYS 58  58  58  LYS LYS J . n 
F 2 59  MET 59  59  59  MET MET J . n 
F 2 60  ASN 60  60  60  ASN ASN J . n 
F 2 61  THR 61  61  61  THR THR J . n 
F 2 62  GLN 62  62  62  GLN GLN J . n 
F 2 63  PHE 63  63  63  PHE PHE J . n 
F 2 64  GLU 64  64  64  GLU GLU J . n 
F 2 65  ALA 65  65  65  ALA ALA J . n 
F 2 66  VAL 66  66  66  VAL VAL J . n 
F 2 67  GLY 67  67  67  GLY GLY J . n 
F 2 68  ARG 68  68  68  ARG ARG J . n 
F 2 69  GLU 69  69  69  GLU GLU J . n 
F 2 70  PHE 70  70  70  PHE PHE J . n 
F 2 71  ASN 71  71  71  ASN ASN J . n 
F 2 72  ASN 72  72  72  ASN ASN J . n 
F 2 73  LEU 73  73  73  LEU LEU J . n 
F 2 74  GLU 74  74  74  GLU GLU J . n 
F 2 75  ARG 75  75  75  ARG ARG J . n 
F 2 76  ARG 76  76  76  ARG ARG J . n 
F 2 77  ILE 77  77  77  ILE ILE J . n 
F 2 78  GLU 78  78  78  GLU GLU J . n 
F 2 79  ASN 79  79  79  ASN ASN J . n 
F 2 80  LEU 80  80  80  LEU LEU J . n 
F 2 81  ASN 81  81  81  ASN ASN J . n 
F 2 82  LYS 82  82  82  LYS LYS J . n 
F 2 83  LYS 83  83  83  LYS LYS J . n 
F 2 84  MET 84  84  84  MET MET J . n 
F 2 85  GLU 85  85  85  GLU GLU J . n 
F 2 86  ASP 86  86  86  ASP ASP J . n 
F 2 87  GLY 87  87  87  GLY GLY J . n 
F 2 88  PHE 88  88  88  PHE PHE J . n 
F 2 89  LEU 89  89  89  LEU LEU J . n 
F 2 90  ASP 90  90  90  ASP ASP J . n 
F 2 91  VAL 91  91  91  VAL VAL J . n 
F 2 92  TRP 92  92  92  TRP TRP J . n 
F 2 93  THR 93  93  93  THR THR J . n 
F 2 94  TYR 94  94  94  TYR TYR J . n 
F 2 95  ASN 95  95  95  ASN ASN J . n 
F 2 96  ALA 96  96  96  ALA ALA J . n 
F 2 97  GLU 97  97  97  GLU GLU J . n 
F 2 98  LEU 98  98  98  LEU LEU J . n 
F 2 99  LEU 99  99  99  LEU LEU J . n 
F 2 100 VAL 100 100 100 VAL VAL J . n 
F 2 101 LEU 101 101 101 LEU LEU J . n 
F 2 102 MET 102 102 102 MET MET J . n 
F 2 103 GLU 103 103 103 GLU GLU J . n 
F 2 104 ASN 104 104 104 ASN ASN J . n 
F 2 105 GLU 105 105 105 GLU GLU J . n 
F 2 106 ARG 106 106 106 ARG ARG J . n 
F 2 107 THR 107 107 107 THR THR J . n 
F 2 108 LEU 108 108 108 LEU LEU J . n 
F 2 109 ASP 109 109 109 ASP ASP J . n 
F 2 110 PHE 110 110 110 PHE PHE J . n 
F 2 111 HIS 111 111 111 HIS HIS J . n 
F 2 112 ASP 112 112 112 ASP ASP J . n 
F 2 113 SER 113 113 113 SER SER J . n 
F 2 114 ASN 114 114 114 ASN ASN J . n 
F 2 115 VAL 115 115 115 VAL VAL J . n 
F 2 116 LYS 116 116 116 LYS LYS J . n 
F 2 117 ASN 117 117 117 ASN ASN J . n 
F 2 118 LEU 118 118 118 LEU LEU J . n 
F 2 119 TYR 119 119 119 TYR TYR J . n 
F 2 120 ASP 120 120 120 ASP ASP J . n 
F 2 121 LYS 121 121 121 LYS LYS J . n 
F 2 122 VAL 122 122 122 VAL VAL J . n 
F 2 123 ARG 123 123 123 ARG ARG J . n 
F 2 124 LEU 124 124 124 LEU LEU J . n 
F 2 125 GLN 125 125 125 GLN GLN J . n 
F 2 126 LEU 126 126 126 LEU LEU J . n 
F 2 127 ARG 127 127 127 ARG ARG J . n 
F 2 128 ASP 128 128 128 ASP ASP J . n 
F 2 129 ASN 129 129 129 ASN ASN J . n 
F 2 130 ALA 130 130 130 ALA ALA J . n 
F 2 131 LYS 131 131 131 LYS LYS J . n 
F 2 132 GLU 132 132 132 GLU GLU J . n 
F 2 133 LEU 133 133 133 LEU LEU J . n 
F 2 134 GLY 134 134 134 GLY GLY J . n 
F 2 135 ASN 135 135 135 ASN ASN J . n 
F 2 136 GLY 136 136 136 GLY GLY J . n 
F 2 137 CYS 137 137 137 CYS CYS J . n 
F 2 138 PHE 138 138 138 PHE PHE J . n 
F 2 139 GLU 139 139 139 GLU GLU J . n 
F 2 140 PHE 140 140 140 PHE PHE J . n 
F 2 141 TYR 141 141 141 TYR TYR J . n 
F 2 142 HIS 142 142 142 HIS HIS J . n 
F 2 143 LYS 143 143 143 LYS LYS J . n 
F 2 144 CYS 144 144 144 CYS CYS J . n 
F 2 145 ASP 145 145 145 ASP ASP J . n 
F 2 146 ASN 146 146 146 ASN ASN J . n 
F 2 147 GLU 147 147 147 GLU GLU J . n 
F 2 148 CYS 148 148 148 CYS CYS J . n 
F 2 149 MET 149 149 149 MET MET J . n 
F 2 150 GLU 150 150 150 GLU GLU J . n 
F 2 151 SER 151 151 151 SER SER J . n 
F 2 152 VAL 152 152 152 VAL VAL J . n 
F 2 153 ARG 153 153 153 ARG ARG J . n 
F 2 154 ASN 154 154 154 ASN ASN J . n 
F 2 155 GLY 155 155 155 GLY GLY J . n 
F 2 156 THR 156 156 156 THR THR J . n 
F 2 157 TYR 157 157 157 TYR TYR J . n 
F 2 158 ASP 158 158 158 ASP ASP J . n 
F 2 159 TYR 159 159 159 TYR TYR J . n 
F 2 160 PRO 160 160 160 PRO PRO J . n 
F 2 161 GLN 161 161 161 GLN GLN J . n 
F 2 162 TYR 162 162 162 TYR TYR J . n 
F 2 163 SER 163 163 163 SER SER J . n 
F 2 164 GLU 164 164 164 GLU GLU J . n 
F 2 165 GLU 165 165 165 GLU GLU J . n 
F 2 166 ALA 166 166 166 ALA ALA J . n 
F 2 167 ARG 167 167 167 ARG ARG J . n 
F 2 168 LEU 168 168 168 LEU LEU J . n 
F 2 169 LYS 169 169 169 LYS LYS J . n 
F 2 170 ARG 170 170 170 ARG ARG J . n 
F 2 171 GLU 171 171 171 GLU GLU J . n 
F 2 172 GLU 172 172 172 GLU GLU J . n 
F 2 173 ILE 173 173 173 ILE ILE J . n 
F 2 174 SER 174 174 174 SER SER J . n 
F 2 175 SER 175 175 ?   ?   ?   J . n 
F 2 176 GLY 176 176 ?   ?   ?   J . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
G 3 GAL 1 E GAL 1 E GAL 1 n 
G 3 NAG 2 E NAG 2 E NAG 2 n 
G 3 GAL 3 E GAL 3 E GAL 3 n 
G 3 SIA 4 E SIA 4 E SIA 4 n 
H 4 GLC 1 F GLC 1 F GLC 1 n 
H 4 GAL 2 F GAL 2 F GAL 2 n 
H 4 NAG 3 F NAG 3 F NAG 3 n 
H 4 GAL 4 F GAL 4 F GAL 4 n 
H 4 SIA 5 F SIA 5 F SIA 5 n 
I 5 NAG 1 G NAG 1 G NAG 1 n 
I 5 NAG 2 G NAG 2 G NAG 2 n 
J 4 GLC 1 H GLC 1 H GLC 1 n 
J 4 GAL 2 H GAL 2 H GAL 2 n 
J 4 NAG 3 H NAG 3 H NAG 3 n 
J 4 GAL 4 H GAL 4 H GAL 4 n 
J 4 SIA 5 H SIA 5 H SIA 5 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 GAL ? ? GAL ? ? 'SUBJECT OF INVESTIGATION' ? 
2 GLC ? ? GLC ? ? 'SUBJECT OF INVESTIGATION' ? 
3 NAG ? ? NAG ? ? 'SUBJECT OF INVESTIGATION' ? 
4 SIA ? ? SIA ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
K 6 NAG 1  401 405 NAG NAG A . 
L 6 NAG 1  401 406 NAG NAG I . 
M 7 HOH 1  501 136 HOH HOH A . 
M 7 HOH 2  502 113 HOH HOH A . 
M 7 HOH 3  503 177 HOH HOH A . 
M 7 HOH 4  504 188 HOH HOH A . 
M 7 HOH 5  505 201 HOH HOH A . 
M 7 HOH 6  506 222 HOH HOH A . 
M 7 HOH 7  507 150 HOH HOH A . 
M 7 HOH 8  508 203 HOH HOH A . 
M 7 HOH 9  509 149 HOH HOH A . 
M 7 HOH 10 510 120 HOH HOH A . 
M 7 HOH 11 511 118 HOH HOH A . 
M 7 HOH 12 512 115 HOH HOH A . 
M 7 HOH 13 513 124 HOH HOH A . 
M 7 HOH 14 514 134 HOH HOH A . 
M 7 HOH 15 515 92  HOH HOH A . 
M 7 HOH 16 516 106 HOH HOH A . 
M 7 HOH 17 517 121 HOH HOH A . 
M 7 HOH 18 518 208 HOH HOH A . 
M 7 HOH 19 519 40  HOH HOH A . 
M 7 HOH 20 520 209 HOH HOH A . 
M 7 HOH 21 521 187 HOH HOH A . 
M 7 HOH 22 522 167 HOH HOH A . 
M 7 HOH 23 523 132 HOH HOH A . 
M 7 HOH 24 524 67  HOH HOH A . 
M 7 HOH 25 525 41  HOH HOH A . 
M 7 HOH 26 526 43  HOH HOH A . 
M 7 HOH 27 527 144 HOH HOH A . 
M 7 HOH 28 528 216 HOH HOH A . 
M 7 HOH 29 529 215 HOH HOH A . 
M 7 HOH 30 530 127 HOH HOH A . 
M 7 HOH 31 531 42  HOH HOH A . 
M 7 HOH 32 532 191 HOH HOH A . 
M 7 HOH 33 533 197 HOH HOH A . 
M 7 HOH 34 534 84  HOH HOH A . 
M 7 HOH 35 535 140 HOH HOH A . 
M 7 HOH 36 536 114 HOH HOH A . 
N 7 HOH 1  201 87  HOH HOH B . 
N 7 HOH 2  202 198 HOH HOH B . 
N 7 HOH 3  203 52  HOH HOH B . 
N 7 HOH 4  204 206 HOH HOH B . 
N 7 HOH 5  205 153 HOH HOH B . 
N 7 HOH 6  206 12  HOH HOH B . 
N 7 HOH 7  207 47  HOH HOH B . 
N 7 HOH 8  208 205 HOH HOH B . 
N 7 HOH 9  209 64  HOH HOH B . 
O 7 HOH 1  401 152 HOH HOH C . 
O 7 HOH 2  402 51  HOH HOH C . 
O 7 HOH 3  403 25  HOH HOH C . 
O 7 HOH 4  404 8   HOH HOH C . 
O 7 HOH 5  405 183 HOH HOH C . 
O 7 HOH 6  406 32  HOH HOH C . 
O 7 HOH 7  407 48  HOH HOH C . 
O 7 HOH 8  408 50  HOH HOH C . 
O 7 HOH 9  409 63  HOH HOH C . 
O 7 HOH 10 410 148 HOH HOH C . 
O 7 HOH 11 411 130 HOH HOH C . 
O 7 HOH 12 412 189 HOH HOH C . 
O 7 HOH 13 413 33  HOH HOH C . 
O 7 HOH 14 414 160 HOH HOH C . 
O 7 HOH 15 415 210 HOH HOH C . 
O 7 HOH 16 416 34  HOH HOH C . 
O 7 HOH 17 417 126 HOH HOH C . 
O 7 HOH 18 418 54  HOH HOH C . 
O 7 HOH 19 419 195 HOH HOH C . 
O 7 HOH 20 420 61  HOH HOH C . 
O 7 HOH 21 421 5   HOH HOH C . 
O 7 HOH 22 422 145 HOH HOH C . 
O 7 HOH 23 423 116 HOH HOH C . 
O 7 HOH 24 424 141 HOH HOH C . 
O 7 HOH 25 425 58  HOH HOH C . 
O 7 HOH 26 426 158 HOH HOH C . 
O 7 HOH 27 427 103 HOH HOH C . 
O 7 HOH 28 428 151 HOH HOH C . 
O 7 HOH 29 429 66  HOH HOH C . 
O 7 HOH 30 430 192 HOH HOH C . 
O 7 HOH 31 431 131 HOH HOH C . 
O 7 HOH 32 432 219 HOH HOH C . 
O 7 HOH 33 433 174 HOH HOH C . 
O 7 HOH 34 434 186 HOH HOH C . 
O 7 HOH 35 435 213 HOH HOH C . 
O 7 HOH 36 436 129 HOH HOH C . 
O 7 HOH 37 437 22  HOH HOH C . 
O 7 HOH 38 438 53  HOH HOH C . 
O 7 HOH 39 439 147 HOH HOH C . 
O 7 HOH 40 440 93  HOH HOH C . 
O 7 HOH 41 441 76  HOH HOH C . 
O 7 HOH 42 442 155 HOH HOH C . 
O 7 HOH 43 443 202 HOH HOH C . 
O 7 HOH 44 444 214 HOH HOH C . 
O 7 HOH 45 445 142 HOH HOH C . 
P 7 HOH 1  201 79  HOH HOH D . 
P 7 HOH 2  202 166 HOH HOH D . 
P 7 HOH 3  203 73  HOH HOH D . 
P 7 HOH 4  204 95  HOH HOH D . 
Q 7 HOH 1  501 88  HOH HOH I . 
Q 7 HOH 2  502 26  HOH HOH I . 
Q 7 HOH 3  503 19  HOH HOH I . 
Q 7 HOH 4  504 164 HOH HOH I . 
Q 7 HOH 5  505 128 HOH HOH I . 
Q 7 HOH 6  506 96  HOH HOH I . 
Q 7 HOH 7  507 104 HOH HOH I . 
Q 7 HOH 8  508 59  HOH HOH I . 
Q 7 HOH 9  509 28  HOH HOH I . 
Q 7 HOH 10 510 7   HOH HOH I . 
Q 7 HOH 11 511 175 HOH HOH I . 
Q 7 HOH 12 512 137 HOH HOH I . 
Q 7 HOH 13 513 159 HOH HOH I . 
Q 7 HOH 14 514 69  HOH HOH I . 
Q 7 HOH 15 515 70  HOH HOH I . 
Q 7 HOH 16 516 171 HOH HOH I . 
Q 7 HOH 17 517 162 HOH HOH I . 
Q 7 HOH 18 518 180 HOH HOH I . 
Q 7 HOH 19 519 31  HOH HOH I . 
Q 7 HOH 20 520 99  HOH HOH I . 
Q 7 HOH 21 521 89  HOH HOH I . 
Q 7 HOH 22 522 207 HOH HOH I . 
Q 7 HOH 23 523 125 HOH HOH I . 
Q 7 HOH 24 524 101 HOH HOH I . 
Q 7 HOH 25 525 102 HOH HOH I . 
Q 7 HOH 26 526 117 HOH HOH I . 
Q 7 HOH 27 527 163 HOH HOH I . 
Q 7 HOH 28 528 212 HOH HOH I . 
Q 7 HOH 29 529 90  HOH HOH I . 
Q 7 HOH 30 530 179 HOH HOH I . 
Q 7 HOH 31 531 110 HOH HOH I . 
Q 7 HOH 32 532 181 HOH HOH I . 
Q 7 HOH 33 533 184 HOH HOH I . 
Q 7 HOH 34 534 165 HOH HOH I . 
Q 7 HOH 35 535 119 HOH HOH I . 
Q 7 HOH 36 536 199 HOH HOH I . 
Q 7 HOH 37 537 173 HOH HOH I . 
Q 7 HOH 38 538 204 HOH HOH I . 
Q 7 HOH 39 539 196 HOH HOH I . 
R 7 HOH 1  201 45  HOH HOH J . 
R 7 HOH 2  202 65  HOH HOH J . 
R 7 HOH 3  203 91  HOH HOH J . 
R 7 HOH 4  204 217 HOH HOH J . 
R 7 HOH 5  205 39  HOH HOH J . 
R 7 HOH 6  206 193 HOH HOH J . 
R 7 HOH 7  207 211 HOH HOH J . 
R 7 HOH 8  208 169 HOH HOH J . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.21rc1_5127: ???)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .                     2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .                     3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .                     4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   96.21 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DIP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     103.539 
_cell.length_a_esd                 ? 
_cell.length_b                     74.760 
_cell.length_b_esd                 ? 
_cell.length_c                     131.101 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DIP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DIP 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.96 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58.46 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1M Hepes 20% PEG6000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-07-30 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9DIP 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.32 
_reflns.d_resolution_low                               31.38 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     85509 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.15 
_reflns.pdbx_Rpim_I_all                                0.06 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.98 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.32 
_reflns_shell.d_res_low                                     2.36 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             8523 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               2 
_reflns_shell.pdbx_Rpim_I_all                               0.78 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.34 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9DIP 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.32 
_refine.ls_d_res_low                             31.18 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     85509 
_refine.ls_number_reflns_R_free                  4311 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.34 
_refine.ls_percent_reflns_R_free                 5.04 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2185 
_refine.ls_R_factor_R_free                       0.2578 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2163 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.64 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.36 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        11874 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         249 
_refine_hist.number_atoms_solvent             141 
_refine_hist.number_atoms_total               12264 
_refine_hist.d_res_high                       2.32 
_refine_hist.d_res_low                        31.18 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.002  ? 12396 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.533  ? 16789 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 16.800 ? 4505  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.043  ? 1836  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.005  ? 2173  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.32 2.34  . . 130 2481 90.00  . . . . 0.3290 . . . . . . . . . . . 0.3654 
'X-RAY DIFFRACTION' 2.34 2.37  . . 134 2669 99.00  . . . . 0.3046 . . . . . . . . . . . 0.3323 
'X-RAY DIFFRACTION' 2.37 2.40  . . 158 2761 100.00 . . . . 0.2913 . . . . . . . . . . . 0.3681 
'X-RAY DIFFRACTION' 2.40 2.43  . . 150 2693 99.00  . . . . 0.2948 . . . . . . . . . . . 0.3036 
'X-RAY DIFFRACTION' 2.43 2.46  . . 125 2725 100.00 . . . . 0.2957 . . . . . . . . . . . 0.3826 
'X-RAY DIFFRACTION' 2.46 2.50  . . 151 2751 100.00 . . . . 0.2961 . . . . . . . . . . . 0.3241 
'X-RAY DIFFRACTION' 2.50 2.53  . . 147 2675 99.00  . . . . 0.2983 . . . . . . . . . . . 0.3562 
'X-RAY DIFFRACTION' 2.53 2.57  . . 146 2724 99.00  . . . . 0.3022 . . . . . . . . . . . 0.4013 
'X-RAY DIFFRACTION' 2.57 2.61  . . 137 2735 99.00  . . . . 0.2867 . . . . . . . . . . . 0.3193 
'X-RAY DIFFRACTION' 2.61 2.65  . . 133 2744 99.00  . . . . 0.2714 . . . . . . . . . . . 0.3103 
'X-RAY DIFFRACTION' 2.65 2.70  . . 126 2696 99.00  . . . . 0.2655 . . . . . . . . . . . 0.3164 
'X-RAY DIFFRACTION' 2.70 2.75  . . 144 2685 97.00  . . . . 0.2499 . . . . . . . . . . . 0.3330 
'X-RAY DIFFRACTION' 2.75 2.80  . . 156 2667 98.00  . . . . 0.2487 . . . . . . . . . . . 0.3194 
'X-RAY DIFFRACTION' 2.80 2.86  . . 151 2632 97.00  . . . . 0.2483 . . . . . . . . . . . 0.2893 
'X-RAY DIFFRACTION' 2.86 2.92  . . 122 2610 95.00  . . . . 0.2527 . . . . . . . . . . . 0.3300 
'X-RAY DIFFRACTION' 2.92 2.99  . . 150 2743 99.00  . . . . 0.2544 . . . . . . . . . . . 0.3289 
'X-RAY DIFFRACTION' 2.99 3.06  . . 143 2701 100.00 . . . . 0.2739 . . . . . . . . . . . 0.2990 
'X-RAY DIFFRACTION' 3.06 3.14  . . 146 2743 99.00  . . . . 0.2552 . . . . . . . . . . . 0.3386 
'X-RAY DIFFRACTION' 3.14 3.24  . . 152 2724 99.00  . . . . 0.2484 . . . . . . . . . . . 0.3277 
'X-RAY DIFFRACTION' 3.24 3.34  . . 140 2716 99.00  . . . . 0.2457 . . . . . . . . . . . 0.2849 
'X-RAY DIFFRACTION' 3.34 3.46  . . 160 2711 100.00 . . . . 0.2327 . . . . . . . . . . . 0.2685 
'X-RAY DIFFRACTION' 3.46 3.60  . . 156 2722 99.00  . . . . 0.2355 . . . . . . . . . . . 0.3061 
'X-RAY DIFFRACTION' 3.60 3.76  . . 141 2757 99.00  . . . . 0.2163 . . . . . . . . . . . 0.2757 
'X-RAY DIFFRACTION' 3.76 3.96  . . 142 2718 98.00  . . . . 0.2014 . . . . . . . . . . . 0.2488 
'X-RAY DIFFRACTION' 3.96 4.21  . . 121 2625 95.00  . . . . 0.1891 . . . . . . . . . . . 0.2369 
'X-RAY DIFFRACTION' 4.21 4.53  . . 153 2735 98.00  . . . . 0.1809 . . . . . . . . . . . 0.2227 
'X-RAY DIFFRACTION' 4.53 4.98  . . 149 2760 100.00 . . . . 0.1650 . . . . . . . . . . . 0.1858 
'X-RAY DIFFRACTION' 4.98 5.70  . . 161 2763 100.00 . . . . 0.1781 . . . . . . . . . . . 0.2089 
'X-RAY DIFFRACTION' 5.70 7.17  . . 144 2768 99.00  . . . . 0.1957 . . . . . . . . . . . 0.2203 
'X-RAY DIFFRACTION' 7.17 31.18 . . 143 2764 96.00  . . . . 0.1842 . . . . . . . . . . . 0.1941 
# 
_struct.entry_id                     9DIP 
_struct.title                        
'Crystal structure of H5 hemagglutinin from the influenza virus A/Texas/37/2024 (H5N1) with LSTa' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DIP 
_struct_keywords.text            'H1N1, Antibody, Hemagglutinin, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 1 ? 
F N N 2 ? 
G N N 3 ? 
H N N 4 ? 
I N N 5 ? 
J N N 4 ? 
K N N 6 ? 
L N N 6 ? 
M N N 7 ? 
N N N 7 ? 
O N N 7 ? 
P N N 7 ? 
Q N N 7 ? 
R N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A0A6B7HPT9_9INFA A0A6B7HPT9 ? 1 
;DQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEWSYIV
ERANPANDLCYPGSLNDYEELKHLLSRINHFEKILIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKNDAYPTI
KISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPTTYISVGTSTLNQRLVPKIATRSQVNGQRGRMDFFWTILKPNDAIH
FESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATGLRNS
P
;
1   
2 UNP A0A6B7HQ27_9INFA A0A6B7HQ27 ? 2 
;GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENL
NKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYP
QYSEEARLKREEIS
;
330 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9DIP A 5 ? 325 ? A0A6B7HPT9 1   ? 321 ? 11 324 
2 2 9DIP B 1 ? 174 ? A0A6B7HQ27 330 ? 503 ? 1  174 
3 1 9DIP C 5 ? 325 ? A0A6B7HPT9 1   ? 321 ? 11 324 
4 2 9DIP D 1 ? 174 ? A0A6B7HQ27 330 ? 503 ? 1  174 
5 1 9DIP I 5 ? 325 ? A0A6B7HPT9 1   ? 321 ? 11 324 
6 2 9DIP J 1 ? 174 ? A0A6B7HQ27 330 ? 503 ? 1  174 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9DIP ALA A 1   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 7   1  
1 9DIP ASP A 2   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 8   2  
1 9DIP PRO A 3   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 9   3  
1 9DIP GLY A 4   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 10  4  
1 9DIP MET A 108 ? UNP A0A6B7HPT9 LEU 104 conflict         111 5  
1 9DIP GLN A 119 ? UNP A0A6B7HPT9 LEU 115 conflict         122 6  
1 9DIP ILE A 199 ? UNP A0A6B7HPT9 THR 195 conflict         199 7  
1 9DIP ALA A 214 ? UNP A0A6B7HPT9 VAL 210 conflict         214 8  
2 9DIP SER B 175 ? UNP A0A6B7HQ27 ?   ?   'expression tag' 175 9  
2 9DIP GLY B 176 ? UNP A0A6B7HQ27 ?   ?   'expression tag' 176 10 
3 9DIP ALA C 1   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 7   11 
3 9DIP ASP C 2   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 8   12 
3 9DIP PRO C 3   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 9   13 
3 9DIP GLY C 4   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 10  14 
3 9DIP MET C 108 ? UNP A0A6B7HPT9 LEU 104 conflict         111 15 
3 9DIP GLN C 119 ? UNP A0A6B7HPT9 LEU 115 conflict         122 16 
3 9DIP ILE C 199 ? UNP A0A6B7HPT9 THR 195 conflict         199 17 
3 9DIP ALA C 214 ? UNP A0A6B7HPT9 VAL 210 conflict         214 18 
4 9DIP SER D 175 ? UNP A0A6B7HQ27 ?   ?   'expression tag' 175 19 
4 9DIP GLY D 176 ? UNP A0A6B7HQ27 ?   ?   'expression tag' 176 20 
5 9DIP ALA I 1   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 7   21 
5 9DIP ASP I 2   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 8   22 
5 9DIP PRO I 3   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 9   23 
5 9DIP GLY I 4   ? UNP A0A6B7HPT9 ?   ?   'expression tag' 10  24 
5 9DIP MET I 108 ? UNP A0A6B7HPT9 LEU 104 conflict         111 25 
5 9DIP GLN I 119 ? UNP A0A6B7HPT9 LEU 115 conflict         122 26 
5 9DIP ILE I 199 ? UNP A0A6B7HPT9 THR 195 conflict         199 27 
5 9DIP ALA I 214 ? UNP A0A6B7HPT9 VAL 210 conflict         214 28 
6 9DIP SER J 175 ? UNP A0A6B7HQ27 ?   ?   'expression tag' 175 29 
6 9DIP GLY J 176 ? UNP A0A6B7HQ27 ?   ?   'expression tag' 176 30 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 36270 ? 
1 MORE         -138  ? 
1 'SSA (A^2)'  61040 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 60  ? GLY A 67  ? SER A 65  GLY A 72  1 ? 8  
HELX_P HELX_P2  AA2 ASP A 101 ? LEU A 109 ? ASP A 104 LEU A 112 1 ? 9  
HELX_P HELX_P3  AA3 PRO A 122 ? TRP A 126 ? PRO A 125 TRP A 127 5 ? 5  
HELX_P HELX_P4  AA4 ASN A 187 ? LYS A 196 ? ASN A 187 LYS A 196 1 ? 10 
HELX_P HELX_P5  AA5 ASP B 37  ? LYS B 58  ? ASP B 37  LYS B 58  1 ? 22 
HELX_P HELX_P6  AA6 GLU B 74  ? ARG B 127 ? GLU B 74  ARG B 127 1 ? 54 
HELX_P HELX_P7  AA7 ASP B 145 ? ASN B 154 ? ASP B 145 ASN B 154 1 ? 10 
HELX_P HELX_P8  AA8 ASP B 158 ? GLU B 171 ? ASP B 158 GLU B 171 1 ? 14 
HELX_P HELX_P9  AA9 SER C 60  ? GLY C 67  ? SER C 65  GLY C 72  1 ? 8  
HELX_P HELX_P10 AB1 ASP C 101 ? SER C 110 ? ASP C 104 SER C 113 1 ? 10 
HELX_P HELX_P11 AB2 PRO C 122 ? TRP C 126 ? PRO C 125 TRP C 127 5 ? 5  
HELX_P HELX_P12 AB3 ASN C 187 ? LYS C 196 ? ASN C 187 LYS C 196 1 ? 10 
HELX_P HELX_P13 AB4 ASP D 37  ? LYS D 58  ? ASP D 37  LYS D 58  1 ? 22 
HELX_P HELX_P14 AB5 GLU D 74  ? ARG D 127 ? GLU D 74  ARG D 127 1 ? 54 
HELX_P HELX_P15 AB6 ASP D 128 ? ALA D 130 ? ASP D 128 ALA D 130 5 ? 3  
HELX_P HELX_P16 AB7 GLU D 147 ? ASN D 154 ? GLU D 147 ASN D 154 1 ? 8  
HELX_P HELX_P17 AB8 GLU D 164 ? ILE D 173 ? GLU D 164 ILE D 173 1 ? 10 
HELX_P HELX_P18 AB9 SER E 60  ? GLY E 67  ? SER I 65  GLY I 72  1 ? 8  
HELX_P HELX_P19 AC1 ASP E 101 ? LEU E 109 ? ASP I 104 LEU I 112 1 ? 9  
HELX_P HELX_P20 AC2 PRO E 122 ? TRP E 126 ? PRO I 125 TRP I 127 5 ? 5  
HELX_P HELX_P21 AC3 ASN E 187 ? LYS E 196 ? ASN I 187 LYS I 196 1 ? 10 
HELX_P HELX_P22 AC4 ASP F 37  ? LYS F 58  ? ASP J 37  LYS J 58  1 ? 22 
HELX_P HELX_P23 AC5 GLU F 74  ? ARG F 127 ? GLU J 74  ARG J 127 1 ? 54 
HELX_P HELX_P24 AC6 ASP F 145 ? GLY F 155 ? ASP J 145 GLY J 155 1 ? 11 
HELX_P HELX_P25 AC7 ASP F 158 ? GLU F 171 ? ASP J 158 GLU J 171 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 8   SG  ? ? ? 1_555 B CYS 137 SG ? ? A CYS 14  B CYS 137 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf2  disulf ?    ? A CYS 46  SG  ? ? ? 1_555 A CYS 278 SG ? ? A CYS 52  A CYS 277 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf3  disulf ?    ? A CYS 59  SG  ? ? ? 1_555 A CYS 71  SG ? ? A CYS 64  A CYS 76  1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf4  disulf ?    ? A CYS 94  SG  ? ? ? 1_555 A CYS 139 SG ? ? A CYS 97  A CYS 139 1_555 ? ? ? ? ? ? ? 2.036 ? ?               
disulf5  disulf ?    ? A CYS 282 SG  ? ? ? 1_555 A CYS 306 SG ? ? A CYS 281 A CYS 305 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf6  disulf ?    ? B CYS 144 SG  ? ? ? 1_555 B CYS 148 SG ? ? B CYS 144 B CYS 148 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf7  disulf ?    ? C CYS 8   SG  ? ? ? 1_555 D CYS 137 SG ? ? C CYS 14  D CYS 137 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf8  disulf ?    ? C CYS 46  SG  ? ? ? 1_555 C CYS 278 SG ? ? C CYS 52  C CYS 277 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf9  disulf ?    ? C CYS 59  SG  ? ? ? 1_555 C CYS 71  SG ? ? C CYS 64  C CYS 76  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf10 disulf ?    ? C CYS 94  SG  ? ? ? 1_555 C CYS 139 SG ? ? C CYS 97  C CYS 139 1_555 ? ? ? ? ? ? ? 2.036 ? ?               
disulf11 disulf ?    ? C CYS 282 SG  ? ? ? 1_555 C CYS 306 SG ? ? C CYS 281 C CYS 305 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf12 disulf ?    ? E CYS 46  SG  ? ? ? 1_555 E CYS 278 SG ? ? I CYS 52  I CYS 277 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf13 disulf ?    ? E CYS 59  SG  ? ? ? 1_555 E CYS 71  SG ? ? I CYS 64  I CYS 76  1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf14 disulf ?    ? E CYS 94  SG  ? ? ? 1_555 E CYS 139 SG ? ? I CYS 97  I CYS 139 1_555 ? ? ? ? ? ? ? 2.038 ? ?               
disulf15 disulf ?    ? E CYS 282 SG  ? ? ? 1_555 E CYS 306 SG ? ? I CYS 281 I CYS 305 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
covale1  covale one  ? A ASN 169 ND2 ? ? ? 1_555 K NAG .   C1 ? ? A ASN 169 A NAG 401 1_555 ? ? ? ? ? ? ? 1.446 ? N-Glycosylation 
covale2  covale one  ? C ASN 169 ND2 ? ? ? 1_555 I NAG .   C1 ? ? C ASN 169 G NAG 1   1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale3  covale one  ? E ASN 169 ND2 ? ? ? 1_555 L NAG .   C1 ? ? I ASN 169 I NAG 401 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale4  covale both ? G GAL .   O3  ? ? ? 1_555 G NAG .   C1 ? ? E GAL 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.462 ? ?               
covale5  covale both ? G NAG .   O3  ? ? ? 1_555 G GAL .   C1 ? ? E NAG 2   E GAL 3   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale6  covale both ? G GAL .   O3  ? ? ? 1_555 G SIA .   C2 ? ? E GAL 3   E SIA 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale7  covale both ? H GLC .   O4  ? ? ? 1_555 H GAL .   C1 ? ? F GLC 1   F GAL 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale8  covale both ? H GAL .   O3  ? ? ? 1_555 H NAG .   C1 ? ? F GAL 2   F NAG 3   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale9  covale both ? H NAG .   O3  ? ? ? 1_555 H GAL .   C1 ? ? F NAG 3   F GAL 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale10 covale both ? H GAL .   O3  ? ? ? 1_555 H SIA .   C2 ? ? F GAL 4   F SIA 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale11 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale12 covale both ? J GLC .   O4  ? ? ? 1_555 J GAL .   C1 ? ? H GLC 1   H GAL 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale13 covale both ? J GAL .   O3  ? ? ? 1_555 J NAG .   C1 ? ? H GAL 2   H NAG 3   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale14 covale both ? J NAG .   O3  ? ? ? 1_555 J GAL .   C1 ? ? H NAG 3   H GAL 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale15 covale both ? J GAL .   O3  ? ? ? 1_555 J SIA .   C2 ? ? H GAL 4   H SIA 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG I .   ? ASN C 169 ? NAG G 1   ? 1_555 ASN C 169 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG K .   ? ASN A 169 ? NAG A 401 ? 1_555 ASN A 169 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG L .   ? ASN E 169 ? NAG I 401 ? 1_555 ASN I 169 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  CYS A 8   ? CYS B 137 ? CYS A 14  ? 1_555 CYS B 137 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS A 46  ? CYS A 278 ? CYS A 52  ? 1_555 CYS A 277 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS A 59  ? CYS A 71  ? CYS A 64  ? 1_555 CYS A 76  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS A 94  ? CYS A 139 ? CYS A 97  ? 1_555 CYS A 139 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS A 282 ? CYS A 306 ? CYS A 281 ? 1_555 CYS A 305 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS B 144 ? CYS B 148 ? CYS B 144 ? 1_555 CYS B 148 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS C 8   ? CYS D 137 ? CYS C 14  ? 1_555 CYS D 137 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS C 46  ? CYS C 278 ? CYS C 52  ? 1_555 CYS C 277 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS C 59  ? CYS C 71  ? CYS C 64  ? 1_555 CYS C 76  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS C 94  ? CYS C 139 ? CYS C 97  ? 1_555 CYS C 139 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
14 CYS C 282 ? CYS C 306 ? CYS C 281 ? 1_555 CYS C 305 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
15 CYS E 46  ? CYS E 278 ? CYS I 52  ? 1_555 CYS I 277 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
16 CYS E 59  ? CYS E 71  ? CYS I 64  ? 1_555 CYS I 76  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS E 94  ? CYS E 139 ? CYS I 97  ? 1_555 CYS I 139 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS E 282 ? CYS E 306 ? CYS I 281 ? 1_555 CYS I 305 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
AA7 ? 5 ? 
AA8 ? 5 ? 
AA9 ? 2 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 5 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 3 ? 
AB8 ? 2 ? 
AB9 ? 3 ? 
AC1 ? 5 ? 
AC2 ? 5 ? 
AC3 ? 2 ? 
AC4 ? 4 ? 
AC5 ? 4 ? 
AC6 ? 5 ? 
AC7 ? 2 ? 
AC8 ? 2 ? 
AC9 ? 3 ? 
AD1 ? 2 ? 
AD2 ? 3 ? 
AD3 ? 5 ? 
AD4 ? 5 ? 
AD5 ? 2 ? 
AD6 ? 4 ? 
AD7 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA5 1 2 ? parallel      
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? parallel      
AB8 1 2 ? parallel      
AB9 1 2 ? parallel      
AB9 2 3 ? parallel      
AC1 1 2 ? parallel      
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC1 4 5 ? anti-parallel 
AC2 1 2 ? parallel      
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC6 4 5 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC9 1 2 ? parallel      
AC9 2 3 ? parallel      
AD1 1 2 ? parallel      
AD2 1 2 ? parallel      
AD2 2 3 ? parallel      
AD3 1 2 ? parallel      
AD3 2 3 ? anti-parallel 
AD3 3 4 ? anti-parallel 
AD3 4 5 ? anti-parallel 
AD4 1 2 ? parallel      
AD4 2 3 ? anti-parallel 
AD4 3 4 ? anti-parallel 
AD4 4 5 ? anti-parallel 
AD5 1 2 ? anti-parallel 
AD6 1 2 ? anti-parallel 
AD6 2 3 ? anti-parallel 
AD6 3 4 ? anti-parallel 
AD7 1 2 ? anti-parallel 
AD7 2 3 ? anti-parallel 
AD7 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY B 31  ? ALA B 36  ? GLY B 31  ALA B 36  
AA1 2 TYR B 22  ? ASN B 28  ? TYR B 22  ASN B 28  
AA1 3 GLN A 6   ? TYR A 11  ? GLN A 12  TYR A 17  
AA1 4 CYS B 137 ? PHE B 140 ? CYS B 137 PHE B 140 
AA1 5 ALA B 130 ? GLU B 132 ? ALA B 130 GLU B 132 
AA2 1 GLU A 18  ? VAL A 20  ? GLU A 24  VAL A 26  
AA2 2 VAL A 28  ? VAL A 30  ? VAL A 34  VAL A 36  
AA3 1 ALA A 33  ? ASP A 35  ? ALA A 39  ASP A 41  
AA3 2 VAL A 316 ? ALA A 318 ? VAL A 315 ALA A 317 
AA4 1 LEU A 37  ? GLU A 38  ? LEU A 43  GLU A 44  
AA4 2 PHE A 295 ? HIS A 296 ? PHE A 294 HIS A 295 
AA4 3 LYS A 308 ? TYR A 309 ? LYS A 307 TYR A 308 
AA5 1 LEU A 45  ? LEU A 48  ? LEU A 51  LEU A 54  
AA5 2 TYR A 275 ? THR A 280 ? TYR A 274 THR A 279 
AA6 1 LEU A 54  ? ILE A 55  ? LEU A 59  ILE A 60  
AA6 2 ILE A 83  ? GLU A 85  ? ILE A 87  GLU A 89  
AA6 3 ILE A 268 ? LYS A 270 ? ILE A 267 LYS A 269 
AA7 1 GLY A 97  ? LEU A 99  ? GLY A 100 LEU A 102 
AA7 2 ARG A 229 ? LEU A 237 ? ARG A 229 LEU A 237 
AA7 3 ASP A 175 ? HIS A 184 ? ASP A 175 HIS A 184 
AA7 4 TYR A 256 ? VAL A 261 A TYR A 256 VAL A 260 
AA7 5 HIS A 114 ? GLN A 119 ? HIS A 117 GLN A 122 
AA8 1 GLY A 97  ? LEU A 99  ? GLY A 100 LEU A 102 
AA8 2 ARG A 229 ? LEU A 237 ? ARG A 229 LEU A 237 
AA8 3 ASP A 175 ? HIS A 184 ? ASP A 175 HIS A 184 
AA8 4 PHE A 251 ? PRO A 254 ? PHE A 251 PRO A 254 
AA8 5 VAL A 151 ? TRP A 153 ? VAL A 151 TRP A 153 
AA9 1 SER A 136 ? PRO A 140 ? SER A 136 PRO A 140 
AA9 2 PRO A 145 ? SER A 146 ? PRO A 145 SER A 146 
AB1 1 ILE A 164 ? ASN A 169 ? ILE A 164 ASN A 169 
AB1 2 ALA A 242 ? SER A 247 ? ALA A 242 SER A 247 
AB1 3 ILE A 202 ? GLY A 205 ? ILE A 202 GLY A 205 
AB1 4 ASN A 210 ? LEU A 213 ? ASN A 210 LEU A 213 
AB2 1 GLY A 287 ? ALA A 288 ? GLY A 286 ALA A 287 
AB2 2 CYS A 282 ? THR A 284 ? CYS A 281 THR A 283 
AB2 3 ILE A 303 ? GLU A 305 ? ILE A 302 GLU A 304 
AB2 4 PHE B 63  ? ALA B 65  ? PHE B 63  ALA B 65  
AB3 1 GLY D 13  ? TRP D 14  ? GLY D 13  TRP D 14  
AB3 2 GLY C 10  ? HIS C 12  ? GLY C 16  HIS C 18  
AB3 3 TYR D 22  ? ASN D 28  ? TYR D 22  ASN D 28  
AB3 4 GLY D 31  ? ALA D 36  ? GLY D 31  ALA D 36  
AB4 1 GLY D 13  ? TRP D 14  ? GLY D 13  TRP D 14  
AB4 2 GLY C 10  ? HIS C 12  ? GLY C 16  HIS C 18  
AB4 3 TYR D 22  ? ASN D 28  ? TYR D 22  ASN D 28  
AB4 4 GLN C 6   ? ILE C 7   ? GLN C 12  ILE C 13  
AB4 5 PHE D 138 ? GLU D 139 ? PHE D 138 GLU D 139 
AB5 1 GLN C 19  ? VAL C 20  ? GLN C 25  VAL C 26  
AB5 2 VAL C 28  ? THR C 29  ? VAL C 34  THR C 35  
AB6 1 ALA C 33  ? ASP C 35  ? ALA C 39  ASP C 41  
AB6 2 VAL C 316 ? ALA C 318 ? VAL C 315 ALA C 317 
AB7 1 LEU C 37  ? GLU C 38  ? LEU C 43  GLU C 44  
AB7 2 PHE C 295 ? HIS C 296 ? PHE C 294 HIS C 295 
AB7 3 LYS C 308 ? TYR C 309 ? LYS C 307 TYR C 308 
AB8 1 LEU C 45  ? LEU C 48  ? LEU C 51  LEU C 54  
AB8 2 TYR C 275 ? THR C 280 ? TYR C 274 THR C 279 
AB9 1 LEU C 54  ? ILE C 55  ? LEU C 59  ILE C 60  
AB9 2 ILE C 83  ? GLU C 85  ? ILE C 87  GLU C 89  
AB9 3 ILE C 268 ? LYS C 270 ? ILE C 267 LYS C 269 
AC1 1 GLY C 97  ? LEU C 99  ? GLY C 100 LEU C 102 
AC1 2 ARG C 229 ? LEU C 237 ? ARG C 229 LEU C 237 
AC1 3 ASP C 175 ? HIS C 184 ? ASP C 175 HIS C 184 
AC1 4 TYR C 256 ? VAL C 261 A TYR C 256 VAL C 260 
AC1 5 HIS C 114 ? GLN C 119 ? HIS C 117 GLN C 122 
AC2 1 GLY C 97  ? LEU C 99  ? GLY C 100 LEU C 102 
AC2 2 ARG C 229 ? LEU C 237 ? ARG C 229 LEU C 237 
AC2 3 ASP C 175 ? HIS C 184 ? ASP C 175 HIS C 184 
AC2 4 PHE C 251 ? PRO C 254 ? PHE C 251 PRO C 254 
AC2 5 VAL C 151 ? TRP C 153 ? VAL C 151 TRP C 153 
AC3 1 SER C 136 ? TYR C 141 ? SER C 136 TYR C 141 
AC3 2 ALA C 144 ? SER C 146 ? ALA C 144 SER C 146 
AC4 1 ILE C 164 ? ASN C 169 ? ILE C 164 ASN C 169 
AC4 2 ALA C 242 ? SER C 247 ? ALA C 242 SER C 247 
AC4 3 ILE C 202 ? GLY C 205 ? ILE C 202 GLY C 205 
AC4 4 ASN C 210 ? LEU C 213 ? ASN C 210 LEU C 213 
AC5 1 GLY C 287 ? ALA C 288 ? GLY C 286 ALA C 287 
AC5 2 CYS C 282 ? THR C 284 ? CYS C 281 THR C 283 
AC5 3 ILE C 303 ? GLU C 305 ? ILE C 302 GLU C 304 
AC5 4 PHE D 63  ? ALA D 65  ? PHE D 63  ALA D 65  
AC6 1 GLY F 31  ? ALA F 36  ? GLY J 31  ALA J 36  
AC6 2 TYR F 22  ? ASN F 28  ? TYR J 22  ASN J 28  
AC6 3 GLN E 6   ? TYR E 11  ? GLN I 12  TYR I 17  
AC6 4 CYS F 137 ? PHE F 140 ? CYS J 137 PHE J 140 
AC6 5 ALA F 130 ? GLU F 132 ? ALA J 130 GLU J 132 
AC7 1 GLN E 19  ? VAL E 20  ? GLN I 25  VAL I 26  
AC7 2 VAL E 28  ? THR E 29  ? VAL I 34  THR I 35  
AC8 1 ALA E 33  ? ASP E 35  ? ALA I 39  ASP I 41  
AC8 2 VAL E 316 ? ALA E 318 ? VAL I 315 ALA I 317 
AC9 1 LEU E 37  ? GLU E 38  ? LEU I 43  GLU I 44  
AC9 2 PHE E 295 ? HIS E 296 ? PHE I 294 HIS I 295 
AC9 3 LYS E 308 ? TYR E 309 ? LYS I 307 TYR I 308 
AD1 1 LEU E 45  ? LEU E 48  ? LEU I 51  LEU I 54  
AD1 2 TYR E 275 ? THR E 280 ? TYR I 274 THR I 279 
AD2 1 LEU E 54  ? ILE E 55  ? LEU I 59  ILE I 60  
AD2 2 ILE E 83  ? GLU E 85  ? ILE I 87  GLU I 89  
AD2 3 ILE E 268 ? LYS E 270 ? ILE I 267 LYS I 269 
AD3 1 GLY E 97  ? LEU E 99  ? GLY I 100 LEU I 102 
AD3 2 ARG E 229 ? LEU E 237 ? ARG I 229 LEU I 237 
AD3 3 ASP E 175 ? HIS E 184 ? ASP I 175 HIS I 184 
AD3 4 TYR E 256 ? VAL E 261 A TYR I 256 VAL I 260 
AD3 5 HIS E 114 ? GLN E 119 ? HIS I 117 GLN I 122 
AD4 1 GLY E 97  ? LEU E 99  ? GLY I 100 LEU I 102 
AD4 2 ARG E 229 ? LEU E 237 ? ARG I 229 LEU I 237 
AD4 3 ASP E 175 ? HIS E 184 ? ASP I 175 HIS I 184 
AD4 4 PHE E 251 ? PRO E 254 ? PHE I 251 PRO I 254 
AD4 5 VAL E 151 ? TRP E 153 ? VAL I 151 TRP I 153 
AD5 1 SER E 136 ? TYR E 141 ? SER I 136 TYR I 141 
AD5 2 ALA E 144 ? SER E 146 ? ALA I 144 SER I 146 
AD6 1 ILE E 164 ? ASN E 169 ? ILE I 164 ASN I 169 
AD6 2 ALA E 242 ? SER E 247 ? ALA I 242 SER I 247 
AD6 3 ILE E 202 ? GLY E 205 ? ILE I 202 GLY I 205 
AD6 4 ASN E 210 ? LEU E 213 ? ASN I 210 LEU I 213 
AD7 1 GLY E 287 ? ALA E 288 ? GLY I 286 ALA I 287 
AD7 2 CYS E 282 ? THR E 284 ? CYS I 281 THR I 283 
AD7 3 ILE E 303 ? GLU E 305 ? ILE I 302 GLU I 304 
AD7 4 PHE F 63  ? ALA F 65  ? PHE J 63  ALA J 65  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA B 35  ? O ALA B 35  N TYR B 24  ? N TYR B 24  
AA1 2 3 O SER B 27  ? O SER B 27  N GLN A 6   ? N GLN A 12  
AA1 3 4 N ILE A 7   ? N ILE A 13  O PHE B 138 ? O PHE B 138 
AA1 4 5 O GLU B 139 ? O GLU B 139 N LYS B 131 ? N LYS B 131 
AA2 1 2 N GLU A 18  ? N GLU A 24  O VAL A 30  ? O VAL A 36  
AA3 1 2 N GLN A 34  ? N GLN A 40  O LEU A 317 ? O LEU A 316 
AA4 1 2 N GLU A 38  ? N GLU A 44  O PHE A 295 ? O PHE A 294 
AA4 2 3 N HIS A 296 ? N HIS A 295 O LYS A 308 ? O LYS A 307 
AA5 1 2 N ASP A 47  ? N ASP A 53  O CYS A 278 ? O CYS A 277 
AA6 1 2 N LEU A 54  ? N LEU A 59  O VAL A 84  ? O VAL A 88  
AA6 2 3 N ILE A 83  ? N ILE A 87  O MET A 269 ? O MET A 268 
AA7 1 2 N SER A 98  ? N SER A 101 O PHE A 232 ? O PHE A 232 
AA7 2 3 O ARG A 229 ? O ARG A 229 N HIS A 184 ? N HIS A 184 
AA7 3 4 N LEU A 177 ? N LEU A 177 O TYR A 258 ? O TYR A 258 
AA7 4 5 O LYS A 259 ? O LYS A 259 N GLU A 116 ? N GLU A 119 
AA8 1 2 N SER A 98  ? N SER A 101 O PHE A 232 ? O PHE A 232 
AA8 2 3 O ARG A 229 ? O ARG A 229 N HIS A 184 ? N HIS A 184 
AA8 3 4 N GLY A 181 ? N GLY A 181 O ILE A 252 ? O ILE A 252 
AA8 4 5 O ALA A 253 ? O ALA A 253 N VAL A 152 ? N VAL A 152 
AA9 1 2 N SER A 136 ? N SER A 136 O SER A 146 ? O SER A 146 
AB1 1 2 N ILE A 164 ? N ILE A 164 O SER A 247 ? O SER A 247 
AB1 2 3 O GLU A 246 ? O GLU A 246 N SER A 203 ? N SER A 203 
AB1 3 4 N ILE A 202 ? N ILE A 202 O LEU A 213 ? O LEU A 213 
AB2 1 2 O GLY A 287 ? O GLY A 286 N THR A 284 ? N THR A 283 
AB2 2 3 N GLN A 283 ? N GLN A 282 O ILE A 303 ? O ILE A 302 
AB2 3 4 N GLY A 304 ? N GLY A 303 O GLU B 64  ? O GLU B 64  
AB3 1 2 O TRP D 14  ? O TRP D 14  N TYR C 11  ? N TYR C 17  
AB3 2 3 N GLY C 10  ? N GLY C 16  O GLY D 23  ? O GLY D 23  
AB3 3 4 N TYR D 24  ? N TYR D 24  O ALA D 35  ? O ALA D 35  
AB4 1 2 O TRP D 14  ? O TRP D 14  N TYR C 11  ? N TYR C 17  
AB4 2 3 N GLY C 10  ? N GLY C 16  O GLY D 23  ? O GLY D 23  
AB4 3 4 O SER D 27  ? O SER D 27  N GLN C 6   ? N GLN C 12  
AB4 4 5 N ILE C 7   ? N ILE C 13  O PHE D 138 ? O PHE D 138 
AB5 1 2 N VAL C 20  ? N VAL C 26  O VAL C 28  ? O VAL C 34  
AB6 1 2 N GLN C 34  ? N GLN C 40  O LEU C 317 ? O LEU C 316 
AB7 1 2 N GLU C 38  ? N GLU C 44  O PHE C 295 ? O PHE C 294 
AB7 2 3 N HIS C 296 ? N HIS C 295 O LYS C 308 ? O LYS C 307 
AB8 1 2 N LEU C 45  ? N LEU C 51  O GLY C 276 ? O GLY C 275 
AB9 1 2 N LEU C 54  ? N LEU C 59  O VAL C 84  ? O VAL C 88  
AB9 2 3 N ILE C 83  ? N ILE C 87  O MET C 269 ? O MET C 268 
AC1 1 2 N SER C 98  ? N SER C 101 O PHE C 232 ? O PHE C 232 
AC1 2 3 O ARG C 229 ? O ARG C 229 N HIS C 184 ? N HIS C 184 
AC1 3 4 N LEU C 177 ? N LEU C 177 O TYR C 258 ? O TYR C 258 
AC1 4 5 O ALA C 257 ? O ALA C 257 N ILE C 118 ? N ILE C 121 
AC2 1 2 N SER C 98  ? N SER C 101 O PHE C 232 ? O PHE C 232 
AC2 2 3 O ARG C 229 ? O ARG C 229 N HIS C 184 ? N HIS C 184 
AC2 3 4 N GLY C 181 ? N GLY C 181 O ILE C 252 ? O ILE C 252 
AC2 4 5 O ALA C 253 ? O ALA C 253 N VAL C 152 ? N VAL C 152 
AC3 1 2 N TYR C 141 ? N TYR C 141 O ALA C 144 ? O ALA C 144 
AC4 1 2 N ILE C 164 ? N ILE C 164 O SER C 247 ? O SER C 247 
AC4 2 3 O GLU C 246 ? O GLU C 246 N SER C 203 ? N SER C 203 
AC4 3 4 N ILE C 202 ? N ILE C 202 O LEU C 213 ? O LEU C 213 
AC5 1 2 O GLY C 287 ? O GLY C 286 N THR C 284 ? N THR C 283 
AC5 2 3 N GLN C 283 ? N GLN C 282 O ILE C 303 ? O ILE C 302 
AC5 3 4 N GLY C 304 ? N GLY C 303 O GLU D 64  ? O GLU D 64  
AC6 1 2 O ALA F 35  ? O ALA J 35  N TYR F 24  ? N TYR J 24  
AC6 2 3 O SER F 27  ? O SER J 27  N GLN E 6   ? N GLN I 12  
AC6 3 4 N ILE E 7   ? N ILE I 13  O PHE F 138 ? O PHE J 138 
AC6 4 5 O GLU F 139 ? O GLU J 139 N LYS F 131 ? N LYS J 131 
AC7 1 2 N VAL E 20  ? N VAL I 26  O VAL E 28  ? O VAL I 34  
AC8 1 2 N GLN E 34  ? N GLN I 40  O LEU E 317 ? O LEU I 316 
AC9 1 2 N GLU E 38  ? N GLU I 44  O PHE E 295 ? O PHE I 294 
AC9 2 3 N HIS E 296 ? N HIS I 295 O LYS E 308 ? O LYS I 307 
AD1 1 2 N ASP E 47  ? N ASP I 53  O THR E 280 ? O THR I 279 
AD2 1 2 N LEU E 54  ? N LEU I 59  O VAL E 84  ? O VAL I 88  
AD2 2 3 N ILE E 83  ? N ILE I 87  O MET E 269 ? O MET I 268 
AD3 1 2 N SER E 98  ? N SER I 101 O PHE E 232 ? O PHE I 232 
AD3 2 3 O ARG E 229 ? O ARG I 229 N HIS E 184 ? N HIS I 184 
AD3 3 4 N LEU E 177 ? N LEU I 177 O TYR E 258 ? O TYR I 258 
AD3 4 5 O LYS E 259 ? O LYS I 259 N GLU E 116 ? N GLU I 119 
AD4 1 2 N SER E 98  ? N SER I 101 O PHE E 232 ? O PHE I 232 
AD4 2 3 O ARG E 229 ? O ARG I 229 N HIS E 184 ? N HIS I 184 
AD4 3 4 N GLY E 181 ? N GLY I 181 O ILE E 252 ? O ILE I 252 
AD4 4 5 O ALA E 253 ? O ALA I 253 N VAL E 152 ? N VAL I 152 
AD5 1 2 N TYR E 141 ? N TYR I 141 O ALA E 144 ? O ALA I 144 
AD6 1 2 N ILE E 164 ? N ILE I 164 O SER E 247 ? O SER I 247 
AD6 2 3 O GLU E 246 ? O GLU I 246 N SER E 203 ? N SER I 203 
AD6 3 4 N ILE E 202 ? N ILE I 202 O LEU E 213 ? O LEU I 213 
AD7 1 2 O GLY E 287 ? O GLY I 286 N THR E 284 ? N THR I 283 
AD7 2 3 N GLN E 283 ? N GLN I 282 O ILE E 303 ? O ILE I 302 
AD7 3 4 N GLY E 304 ? N GLY I 303 O GLU F 64  ? O GLU J 64  
# 
_pdbx_entry_details.entry_id                   9DIP 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NZ A LYS 280 ? ? O   A HOH 501 ? ? 2.06 
2 1 OG A SER 22  ? ? OE1 A GLU 24  ? ? 2.11 
3 1 O  B GLU 103 ? ? OG1 B THR 107 ? ? 2.17 
4 1 O  B LEU 2   ? ? OG  J SER 113 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 96  ? ? -102.72 -61.90  
2  1 TRP A 127 ? ? -118.82 68.77   
3  1 CYS A 139 ? ? -117.88 76.06   
4  1 LYS A 196 ? ? 70.85   -11.65  
5  1 THR A 206 ? ? -127.85 -166.58 
6  1 SER A 265 ? ? -151.03 -159.96 
7  1 ASN B 28  ? ? -128.15 -169.64 
8  1 ARG B 127 ? ? 57.83   -134.36 
9  1 LYS C 196 ? ? 71.14   -11.49  
10 1 GLU D 11  ? ? 37.22   45.28   
11 1 ARG D 127 ? ? 64.68   -134.53 
12 1 LYS I 196 ? ? 71.47   -12.14  
13 1 ARG J 127 ? ? 60.02   -130.01 
14 1 TYR J 141 ? ? -99.84  34.91   
# 
loop_
_pdbx_validate_chiral.id 
_pdbx_validate_chiral.PDB_model_num 
_pdbx_validate_chiral.auth_atom_id 
_pdbx_validate_chiral.label_alt_id 
_pdbx_validate_chiral.auth_asym_id 
_pdbx_validate_chiral.auth_comp_id 
_pdbx_validate_chiral.auth_seq_id 
_pdbx_validate_chiral.PDB_ins_code 
_pdbx_validate_chiral.details 
_pdbx_validate_chiral.omega 
1 1 C1 ? F GLC 1 ? 'WRONG HAND' . 
2 1 C1 ? H GLC 1 ? 'WRONG HAND' . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ALA 7   ? A ALA 1   
2  1 Y 1 A ASP 8   ? A ASP 2   
3  1 Y 1 A PRO 9   ? A PRO 3   
4  1 Y 1 B SER 175 ? B SER 175 
5  1 Y 1 B GLY 176 ? B GLY 176 
6  1 Y 1 C ALA 7   ? C ALA 1   
7  1 Y 1 C ASP 8   ? C ASP 2   
8  1 Y 1 C PRO 9   ? C PRO 3   
9  1 Y 1 D SER 175 ? D SER 175 
10 1 Y 1 D GLY 176 ? D GLY 176 
11 1 Y 1 I ALA 7   ? E ALA 1   
12 1 Y 1 I ASP 8   ? E ASP 2   
13 1 Y 1 I PRO 9   ? E PRO 3   
14 1 Y 1 J SER 175 ? F SER 175 
15 1 Y 1 J GLY 176 ? F GLY 176 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GAL C1   C N R 88  
GAL C2   C N R 89  
GAL C3   C N S 90  
GAL C4   C N R 91  
GAL C5   C N R 92  
GAL C6   C N N 93  
GAL O1   O N N 94  
GAL O2   O N N 95  
GAL O3   O N N 96  
GAL O4   O N N 97  
GAL O5   O N N 98  
GAL O6   O N N 99  
GAL H1   H N N 100 
GAL H2   H N N 101 
GAL H3   H N N 102 
GAL H4   H N N 103 
GAL H5   H N N 104 
GAL H61  H N N 105 
GAL H62  H N N 106 
GAL HO1  H N N 107 
GAL HO2  H N N 108 
GAL HO3  H N N 109 
GAL HO4  H N N 110 
GAL HO6  H N N 111 
GLC C1   C N S 112 
GLC C2   C N R 113 
GLC C3   C N S 114 
GLC C4   C N S 115 
GLC C5   C N R 116 
GLC C6   C N N 117 
GLC O1   O N N 118 
GLC O2   O N N 119 
GLC O3   O N N 120 
GLC O4   O N N 121 
GLC O5   O N N 122 
GLC O6   O N N 123 
GLC H1   H N N 124 
GLC H2   H N N 125 
GLC H3   H N N 126 
GLC H4   H N N 127 
GLC H5   H N N 128 
GLC H61  H N N 129 
GLC H62  H N N 130 
GLC HO1  H N N 131 
GLC HO2  H N N 132 
GLC HO3  H N N 133 
GLC HO4  H N N 134 
GLC HO6  H N N 135 
GLN N    N N N 136 
GLN CA   C N S 137 
GLN C    C N N 138 
GLN O    O N N 139 
GLN CB   C N N 140 
GLN CG   C N N 141 
GLN CD   C N N 142 
GLN OE1  O N N 143 
GLN NE2  N N N 144 
GLN OXT  O N N 145 
GLN H    H N N 146 
GLN H2   H N N 147 
GLN HA   H N N 148 
GLN HB2  H N N 149 
GLN HB3  H N N 150 
GLN HG2  H N N 151 
GLN HG3  H N N 152 
GLN HE21 H N N 153 
GLN HE22 H N N 154 
GLN HXT  H N N 155 
GLU N    N N N 156 
GLU CA   C N S 157 
GLU C    C N N 158 
GLU O    O N N 159 
GLU CB   C N N 160 
GLU CG   C N N 161 
GLU CD   C N N 162 
GLU OE1  O N N 163 
GLU OE2  O N N 164 
GLU OXT  O N N 165 
GLU H    H N N 166 
GLU H2   H N N 167 
GLU HA   H N N 168 
GLU HB2  H N N 169 
GLU HB3  H N N 170 
GLU HG2  H N N 171 
GLU HG3  H N N 172 
GLU HE2  H N N 173 
GLU HXT  H N N 174 
GLY N    N N N 175 
GLY CA   C N N 176 
GLY C    C N N 177 
GLY O    O N N 178 
GLY OXT  O N N 179 
GLY H    H N N 180 
GLY H2   H N N 181 
GLY HA2  H N N 182 
GLY HA3  H N N 183 
GLY HXT  H N N 184 
HIS N    N N N 185 
HIS CA   C N S 186 
HIS C    C N N 187 
HIS O    O N N 188 
HIS CB   C N N 189 
HIS CG   C Y N 190 
HIS ND1  N Y N 191 
HIS CD2  C Y N 192 
HIS CE1  C Y N 193 
HIS NE2  N Y N 194 
HIS OXT  O N N 195 
HIS H    H N N 196 
HIS H2   H N N 197 
HIS HA   H N N 198 
HIS HB2  H N N 199 
HIS HB3  H N N 200 
HIS HD1  H N N 201 
HIS HD2  H N N 202 
HIS HE1  H N N 203 
HIS HE2  H N N 204 
HIS HXT  H N N 205 
HOH O    O N N 206 
HOH H1   H N N 207 
HOH H2   H N N 208 
ILE N    N N N 209 
ILE CA   C N S 210 
ILE C    C N N 211 
ILE O    O N N 212 
ILE CB   C N S 213 
ILE CG1  C N N 214 
ILE CG2  C N N 215 
ILE CD1  C N N 216 
ILE OXT  O N N 217 
ILE H    H N N 218 
ILE H2   H N N 219 
ILE HA   H N N 220 
ILE HB   H N N 221 
ILE HG12 H N N 222 
ILE HG13 H N N 223 
ILE HG21 H N N 224 
ILE HG22 H N N 225 
ILE HG23 H N N 226 
ILE HD11 H N N 227 
ILE HD12 H N N 228 
ILE HD13 H N N 229 
ILE HXT  H N N 230 
LEU N    N N N 231 
LEU CA   C N S 232 
LEU C    C N N 233 
LEU O    O N N 234 
LEU CB   C N N 235 
LEU CG   C N N 236 
LEU CD1  C N N 237 
LEU CD2  C N N 238 
LEU OXT  O N N 239 
LEU H    H N N 240 
LEU H2   H N N 241 
LEU HA   H N N 242 
LEU HB2  H N N 243 
LEU HB3  H N N 244 
LEU HG   H N N 245 
LEU HD11 H N N 246 
LEU HD12 H N N 247 
LEU HD13 H N N 248 
LEU HD21 H N N 249 
LEU HD22 H N N 250 
LEU HD23 H N N 251 
LEU HXT  H N N 252 
LYS N    N N N 253 
LYS CA   C N S 254 
LYS C    C N N 255 
LYS O    O N N 256 
LYS CB   C N N 257 
LYS CG   C N N 258 
LYS CD   C N N 259 
LYS CE   C N N 260 
LYS NZ   N N N 261 
LYS OXT  O N N 262 
LYS H    H N N 263 
LYS H2   H N N 264 
LYS HA   H N N 265 
LYS HB2  H N N 266 
LYS HB3  H N N 267 
LYS HG2  H N N 268 
LYS HG3  H N N 269 
LYS HD2  H N N 270 
LYS HD3  H N N 271 
LYS HE2  H N N 272 
LYS HE3  H N N 273 
LYS HZ1  H N N 274 
LYS HZ2  H N N 275 
LYS HZ3  H N N 276 
LYS HXT  H N N 277 
MET N    N N N 278 
MET CA   C N S 279 
MET C    C N N 280 
MET O    O N N 281 
MET CB   C N N 282 
MET CG   C N N 283 
MET SD   S N N 284 
MET CE   C N N 285 
MET OXT  O N N 286 
MET H    H N N 287 
MET H2   H N N 288 
MET HA   H N N 289 
MET HB2  H N N 290 
MET HB3  H N N 291 
MET HG2  H N N 292 
MET HG3  H N N 293 
MET HE1  H N N 294 
MET HE2  H N N 295 
MET HE3  H N N 296 
MET HXT  H N N 297 
NAG C1   C N R 298 
NAG C2   C N R 299 
NAG C3   C N R 300 
NAG C4   C N S 301 
NAG C5   C N R 302 
NAG C6   C N N 303 
NAG C7   C N N 304 
NAG C8   C N N 305 
NAG N2   N N N 306 
NAG O1   O N N 307 
NAG O3   O N N 308 
NAG O4   O N N 309 
NAG O5   O N N 310 
NAG O6   O N N 311 
NAG O7   O N N 312 
NAG H1   H N N 313 
NAG H2   H N N 314 
NAG H3   H N N 315 
NAG H4   H N N 316 
NAG H5   H N N 317 
NAG H61  H N N 318 
NAG H62  H N N 319 
NAG H81  H N N 320 
NAG H82  H N N 321 
NAG H83  H N N 322 
NAG HN2  H N N 323 
NAG HO1  H N N 324 
NAG HO3  H N N 325 
NAG HO4  H N N 326 
NAG HO6  H N N 327 
PHE N    N N N 328 
PHE CA   C N S 329 
PHE C    C N N 330 
PHE O    O N N 331 
PHE CB   C N N 332 
PHE CG   C Y N 333 
PHE CD1  C Y N 334 
PHE CD2  C Y N 335 
PHE CE1  C Y N 336 
PHE CE2  C Y N 337 
PHE CZ   C Y N 338 
PHE OXT  O N N 339 
PHE H    H N N 340 
PHE H2   H N N 341 
PHE HA   H N N 342 
PHE HB2  H N N 343 
PHE HB3  H N N 344 
PHE HD1  H N N 345 
PHE HD2  H N N 346 
PHE HE1  H N N 347 
PHE HE2  H N N 348 
PHE HZ   H N N 349 
PHE HXT  H N N 350 
PRO N    N N N 351 
PRO CA   C N S 352 
PRO C    C N N 353 
PRO O    O N N 354 
PRO CB   C N N 355 
PRO CG   C N N 356 
PRO CD   C N N 357 
PRO OXT  O N N 358 
PRO H    H N N 359 
PRO HA   H N N 360 
PRO HB2  H N N 361 
PRO HB3  H N N 362 
PRO HG2  H N N 363 
PRO HG3  H N N 364 
PRO HD2  H N N 365 
PRO HD3  H N N 366 
PRO HXT  H N N 367 
SER N    N N N 368 
SER CA   C N S 369 
SER C    C N N 370 
SER O    O N N 371 
SER CB   C N N 372 
SER OG   O N N 373 
SER OXT  O N N 374 
SER H    H N N 375 
SER H2   H N N 376 
SER HA   H N N 377 
SER HB2  H N N 378 
SER HB3  H N N 379 
SER HG   H N N 380 
SER HXT  H N N 381 
SIA C1   C N N 382 
SIA C2   C N R 383 
SIA C3   C N N 384 
SIA C4   C N S 385 
SIA C5   C N R 386 
SIA C6   C N R 387 
SIA C7   C N R 388 
SIA C8   C N R 389 
SIA C9   C N N 390 
SIA C10  C N N 391 
SIA C11  C N N 392 
SIA N5   N N N 393 
SIA O1A  O N N 394 
SIA O1B  O N N 395 
SIA O2   O N N 396 
SIA O4   O N N 397 
SIA O6   O N N 398 
SIA O7   O N N 399 
SIA O8   O N N 400 
SIA O9   O N N 401 
SIA O10  O N N 402 
SIA H32  H N N 403 
SIA H31  H N N 404 
SIA H4   H N N 405 
SIA H5   H N N 406 
SIA H6   H N N 407 
SIA H7   H N N 408 
SIA H8   H N N 409 
SIA H92  H N N 410 
SIA H91  H N N 411 
SIA H111 H N N 412 
SIA H113 H N N 413 
SIA H112 H N N 414 
SIA HN5  H N N 415 
SIA HO1B H N N 416 
SIA HO2  H N N 417 
SIA HO4  H N N 418 
SIA HO7  H N N 419 
SIA HO8  H N N 420 
SIA HO9  H N N 421 
THR N    N N N 422 
THR CA   C N S 423 
THR C    C N N 424 
THR O    O N N 425 
THR CB   C N R 426 
THR OG1  O N N 427 
THR CG2  C N N 428 
THR OXT  O N N 429 
THR H    H N N 430 
THR H2   H N N 431 
THR HA   H N N 432 
THR HB   H N N 433 
THR HG1  H N N 434 
THR HG21 H N N 435 
THR HG22 H N N 436 
THR HG23 H N N 437 
THR HXT  H N N 438 
TRP N    N N N 439 
TRP CA   C N S 440 
TRP C    C N N 441 
TRP O    O N N 442 
TRP CB   C N N 443 
TRP CG   C Y N 444 
TRP CD1  C Y N 445 
TRP CD2  C Y N 446 
TRP NE1  N Y N 447 
TRP CE2  C Y N 448 
TRP CE3  C Y N 449 
TRP CZ2  C Y N 450 
TRP CZ3  C Y N 451 
TRP CH2  C Y N 452 
TRP OXT  O N N 453 
TRP H    H N N 454 
TRP H2   H N N 455 
TRP HA   H N N 456 
TRP HB2  H N N 457 
TRP HB3  H N N 458 
TRP HD1  H N N 459 
TRP HE1  H N N 460 
TRP HE3  H N N 461 
TRP HZ2  H N N 462 
TRP HZ3  H N N 463 
TRP HH2  H N N 464 
TRP HXT  H N N 465 
TYR N    N N N 466 
TYR CA   C N S 467 
TYR C    C N N 468 
TYR O    O N N 469 
TYR CB   C N N 470 
TYR CG   C Y N 471 
TYR CD1  C Y N 472 
TYR CD2  C Y N 473 
TYR CE1  C Y N 474 
TYR CE2  C Y N 475 
TYR CZ   C Y N 476 
TYR OH   O N N 477 
TYR OXT  O N N 478 
TYR H    H N N 479 
TYR H2   H N N 480 
TYR HA   H N N 481 
TYR HB2  H N N 482 
TYR HB3  H N N 483 
TYR HD1  H N N 484 
TYR HD2  H N N 485 
TYR HE1  H N N 486 
TYR HE2  H N N 487 
TYR HH   H N N 488 
TYR HXT  H N N 489 
VAL N    N N N 490 
VAL CA   C N S 491 
VAL C    C N N 492 
VAL O    O N N 493 
VAL CB   C N N 494 
VAL CG1  C N N 495 
VAL CG2  C N N 496 
VAL OXT  O N N 497 
VAL H    H N N 498 
VAL H2   H N N 499 
VAL HA   H N N 500 
VAL HB   H N N 501 
VAL HG11 H N N 502 
VAL HG12 H N N 503 
VAL HG13 H N N 504 
VAL HG21 H N N 505 
VAL HG22 H N N 506 
VAL HG23 H N N 507 
VAL HXT  H N N 508 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GAL C1  C2   sing N N 83  
GAL C1  O1   sing N N 84  
GAL C1  O5   sing N N 85  
GAL C1  H1   sing N N 86  
GAL C2  C3   sing N N 87  
GAL C2  O2   sing N N 88  
GAL C2  H2   sing N N 89  
GAL C3  C4   sing N N 90  
GAL C3  O3   sing N N 91  
GAL C3  H3   sing N N 92  
GAL C4  C5   sing N N 93  
GAL C4  O4   sing N N 94  
GAL C4  H4   sing N N 95  
GAL C5  C6   sing N N 96  
GAL C5  O5   sing N N 97  
GAL C5  H5   sing N N 98  
GAL C6  O6   sing N N 99  
GAL C6  H61  sing N N 100 
GAL C6  H62  sing N N 101 
GAL O1  HO1  sing N N 102 
GAL O2  HO2  sing N N 103 
GAL O3  HO3  sing N N 104 
GAL O4  HO4  sing N N 105 
GAL O6  HO6  sing N N 106 
GLC C1  C2   sing N N 107 
GLC C1  O1   sing N N 108 
GLC C1  O5   sing N N 109 
GLC C1  H1   sing N N 110 
GLC C2  C3   sing N N 111 
GLC C2  O2   sing N N 112 
GLC C2  H2   sing N N 113 
GLC C3  C4   sing N N 114 
GLC C3  O3   sing N N 115 
GLC C3  H3   sing N N 116 
GLC C4  C5   sing N N 117 
GLC C4  O4   sing N N 118 
GLC C4  H4   sing N N 119 
GLC C5  C6   sing N N 120 
GLC C5  O5   sing N N 121 
GLC C5  H5   sing N N 122 
GLC C6  O6   sing N N 123 
GLC C6  H61  sing N N 124 
GLC C6  H62  sing N N 125 
GLC O1  HO1  sing N N 126 
GLC O2  HO2  sing N N 127 
GLC O3  HO3  sing N N 128 
GLC O4  HO4  sing N N 129 
GLC O6  HO6  sing N N 130 
GLN N   CA   sing N N 131 
GLN N   H    sing N N 132 
GLN N   H2   sing N N 133 
GLN CA  C    sing N N 134 
GLN CA  CB   sing N N 135 
GLN CA  HA   sing N N 136 
GLN C   O    doub N N 137 
GLN C   OXT  sing N N 138 
GLN CB  CG   sing N N 139 
GLN CB  HB2  sing N N 140 
GLN CB  HB3  sing N N 141 
GLN CG  CD   sing N N 142 
GLN CG  HG2  sing N N 143 
GLN CG  HG3  sing N N 144 
GLN CD  OE1  doub N N 145 
GLN CD  NE2  sing N N 146 
GLN NE2 HE21 sing N N 147 
GLN NE2 HE22 sing N N 148 
GLN OXT HXT  sing N N 149 
GLU N   CA   sing N N 150 
GLU N   H    sing N N 151 
GLU N   H2   sing N N 152 
GLU CA  C    sing N N 153 
GLU CA  CB   sing N N 154 
GLU CA  HA   sing N N 155 
GLU C   O    doub N N 156 
GLU C   OXT  sing N N 157 
GLU CB  CG   sing N N 158 
GLU CB  HB2  sing N N 159 
GLU CB  HB3  sing N N 160 
GLU CG  CD   sing N N 161 
GLU CG  HG2  sing N N 162 
GLU CG  HG3  sing N N 163 
GLU CD  OE1  doub N N 164 
GLU CD  OE2  sing N N 165 
GLU OE2 HE2  sing N N 166 
GLU OXT HXT  sing N N 167 
GLY N   CA   sing N N 168 
GLY N   H    sing N N 169 
GLY N   H2   sing N N 170 
GLY CA  C    sing N N 171 
GLY CA  HA2  sing N N 172 
GLY CA  HA3  sing N N 173 
GLY C   O    doub N N 174 
GLY C   OXT  sing N N 175 
GLY OXT HXT  sing N N 176 
HIS N   CA   sing N N 177 
HIS N   H    sing N N 178 
HIS N   H2   sing N N 179 
HIS CA  C    sing N N 180 
HIS CA  CB   sing N N 181 
HIS CA  HA   sing N N 182 
HIS C   O    doub N N 183 
HIS C   OXT  sing N N 184 
HIS CB  CG   sing N N 185 
HIS CB  HB2  sing N N 186 
HIS CB  HB3  sing N N 187 
HIS CG  ND1  sing Y N 188 
HIS CG  CD2  doub Y N 189 
HIS ND1 CE1  doub Y N 190 
HIS ND1 HD1  sing N N 191 
HIS CD2 NE2  sing Y N 192 
HIS CD2 HD2  sing N N 193 
HIS CE1 NE2  sing Y N 194 
HIS CE1 HE1  sing N N 195 
HIS NE2 HE2  sing N N 196 
HIS OXT HXT  sing N N 197 
HOH O   H1   sing N N 198 
HOH O   H2   sing N N 199 
ILE N   CA   sing N N 200 
ILE N   H    sing N N 201 
ILE N   H2   sing N N 202 
ILE CA  C    sing N N 203 
ILE CA  CB   sing N N 204 
ILE CA  HA   sing N N 205 
ILE C   O    doub N N 206 
ILE C   OXT  sing N N 207 
ILE CB  CG1  sing N N 208 
ILE CB  CG2  sing N N 209 
ILE CB  HB   sing N N 210 
ILE CG1 CD1  sing N N 211 
ILE CG1 HG12 sing N N 212 
ILE CG1 HG13 sing N N 213 
ILE CG2 HG21 sing N N 214 
ILE CG2 HG22 sing N N 215 
ILE CG2 HG23 sing N N 216 
ILE CD1 HD11 sing N N 217 
ILE CD1 HD12 sing N N 218 
ILE CD1 HD13 sing N N 219 
ILE OXT HXT  sing N N 220 
LEU N   CA   sing N N 221 
LEU N   H    sing N N 222 
LEU N   H2   sing N N 223 
LEU CA  C    sing N N 224 
LEU CA  CB   sing N N 225 
LEU CA  HA   sing N N 226 
LEU C   O    doub N N 227 
LEU C   OXT  sing N N 228 
LEU CB  CG   sing N N 229 
LEU CB  HB2  sing N N 230 
LEU CB  HB3  sing N N 231 
LEU CG  CD1  sing N N 232 
LEU CG  CD2  sing N N 233 
LEU CG  HG   sing N N 234 
LEU CD1 HD11 sing N N 235 
LEU CD1 HD12 sing N N 236 
LEU CD1 HD13 sing N N 237 
LEU CD2 HD21 sing N N 238 
LEU CD2 HD22 sing N N 239 
LEU CD2 HD23 sing N N 240 
LEU OXT HXT  sing N N 241 
LYS N   CA   sing N N 242 
LYS N   H    sing N N 243 
LYS N   H2   sing N N 244 
LYS CA  C    sing N N 245 
LYS CA  CB   sing N N 246 
LYS CA  HA   sing N N 247 
LYS C   O    doub N N 248 
LYS C   OXT  sing N N 249 
LYS CB  CG   sing N N 250 
LYS CB  HB2  sing N N 251 
LYS CB  HB3  sing N N 252 
LYS CG  CD   sing N N 253 
LYS CG  HG2  sing N N 254 
LYS CG  HG3  sing N N 255 
LYS CD  CE   sing N N 256 
LYS CD  HD2  sing N N 257 
LYS CD  HD3  sing N N 258 
LYS CE  NZ   sing N N 259 
LYS CE  HE2  sing N N 260 
LYS CE  HE3  sing N N 261 
LYS NZ  HZ1  sing N N 262 
LYS NZ  HZ2  sing N N 263 
LYS NZ  HZ3  sing N N 264 
LYS OXT HXT  sing N N 265 
MET N   CA   sing N N 266 
MET N   H    sing N N 267 
MET N   H2   sing N N 268 
MET CA  C    sing N N 269 
MET CA  CB   sing N N 270 
MET CA  HA   sing N N 271 
MET C   O    doub N N 272 
MET C   OXT  sing N N 273 
MET CB  CG   sing N N 274 
MET CB  HB2  sing N N 275 
MET CB  HB3  sing N N 276 
MET CG  SD   sing N N 277 
MET CG  HG2  sing N N 278 
MET CG  HG3  sing N N 279 
MET SD  CE   sing N N 280 
MET CE  HE1  sing N N 281 
MET CE  HE2  sing N N 282 
MET CE  HE3  sing N N 283 
MET OXT HXT  sing N N 284 
NAG C1  C2   sing N N 285 
NAG C1  O1   sing N N 286 
NAG C1  O5   sing N N 287 
NAG C1  H1   sing N N 288 
NAG C2  C3   sing N N 289 
NAG C2  N2   sing N N 290 
NAG C2  H2   sing N N 291 
NAG C3  C4   sing N N 292 
NAG C3  O3   sing N N 293 
NAG C3  H3   sing N N 294 
NAG C4  C5   sing N N 295 
NAG C4  O4   sing N N 296 
NAG C4  H4   sing N N 297 
NAG C5  C6   sing N N 298 
NAG C5  O5   sing N N 299 
NAG C5  H5   sing N N 300 
NAG C6  O6   sing N N 301 
NAG C6  H61  sing N N 302 
NAG C6  H62  sing N N 303 
NAG C7  C8   sing N N 304 
NAG C7  N2   sing N N 305 
NAG C7  O7   doub N N 306 
NAG C8  H81  sing N N 307 
NAG C8  H82  sing N N 308 
NAG C8  H83  sing N N 309 
NAG N2  HN2  sing N N 310 
NAG O1  HO1  sing N N 311 
NAG O3  HO3  sing N N 312 
NAG O4  HO4  sing N N 313 
NAG O6  HO6  sing N N 314 
PHE N   CA   sing N N 315 
PHE N   H    sing N N 316 
PHE N   H2   sing N N 317 
PHE CA  C    sing N N 318 
PHE CA  CB   sing N N 319 
PHE CA  HA   sing N N 320 
PHE C   O    doub N N 321 
PHE C   OXT  sing N N 322 
PHE CB  CG   sing N N 323 
PHE CB  HB2  sing N N 324 
PHE CB  HB3  sing N N 325 
PHE CG  CD1  doub Y N 326 
PHE CG  CD2  sing Y N 327 
PHE CD1 CE1  sing Y N 328 
PHE CD1 HD1  sing N N 329 
PHE CD2 CE2  doub Y N 330 
PHE CD2 HD2  sing N N 331 
PHE CE1 CZ   doub Y N 332 
PHE CE1 HE1  sing N N 333 
PHE CE2 CZ   sing Y N 334 
PHE CE2 HE2  sing N N 335 
PHE CZ  HZ   sing N N 336 
PHE OXT HXT  sing N N 337 
PRO N   CA   sing N N 338 
PRO N   CD   sing N N 339 
PRO N   H    sing N N 340 
PRO CA  C    sing N N 341 
PRO CA  CB   sing N N 342 
PRO CA  HA   sing N N 343 
PRO C   O    doub N N 344 
PRO C   OXT  sing N N 345 
PRO CB  CG   sing N N 346 
PRO CB  HB2  sing N N 347 
PRO CB  HB3  sing N N 348 
PRO CG  CD   sing N N 349 
PRO CG  HG2  sing N N 350 
PRO CG  HG3  sing N N 351 
PRO CD  HD2  sing N N 352 
PRO CD  HD3  sing N N 353 
PRO OXT HXT  sing N N 354 
SER N   CA   sing N N 355 
SER N   H    sing N N 356 
SER N   H2   sing N N 357 
SER CA  C    sing N N 358 
SER CA  CB   sing N N 359 
SER CA  HA   sing N N 360 
SER C   O    doub N N 361 
SER C   OXT  sing N N 362 
SER CB  OG   sing N N 363 
SER CB  HB2  sing N N 364 
SER CB  HB3  sing N N 365 
SER OG  HG   sing N N 366 
SER OXT HXT  sing N N 367 
SIA C1  C2   sing N N 368 
SIA C1  O1A  doub N N 369 
SIA C1  O1B  sing N N 370 
SIA C2  C3   sing N N 371 
SIA C2  O2   sing N N 372 
SIA C2  O6   sing N N 373 
SIA C3  C4   sing N N 374 
SIA C3  H32  sing N N 375 
SIA C3  H31  sing N N 376 
SIA C4  C5   sing N N 377 
SIA C4  O4   sing N N 378 
SIA C4  H4   sing N N 379 
SIA C5  C6   sing N N 380 
SIA C5  N5   sing N N 381 
SIA C5  H5   sing N N 382 
SIA C6  C7   sing N N 383 
SIA C6  O6   sing N N 384 
SIA C6  H6   sing N N 385 
SIA C7  C8   sing N N 386 
SIA C7  O7   sing N N 387 
SIA C7  H7   sing N N 388 
SIA C8  C9   sing N N 389 
SIA C8  O8   sing N N 390 
SIA C8  H8   sing N N 391 
SIA C9  O9   sing N N 392 
SIA C9  H92  sing N N 393 
SIA C9  H91  sing N N 394 
SIA C10 C11  sing N N 395 
SIA C10 N5   sing N N 396 
SIA C10 O10  doub N N 397 
SIA C11 H111 sing N N 398 
SIA C11 H113 sing N N 399 
SIA C11 H112 sing N N 400 
SIA N5  HN5  sing N N 401 
SIA O1B HO1B sing N N 402 
SIA O2  HO2  sing N N 403 
SIA O4  HO4  sing N N 404 
SIA O7  HO7  sing N N 405 
SIA O8  HO8  sing N N 406 
SIA O9  HO9  sing N N 407 
THR N   CA   sing N N 408 
THR N   H    sing N N 409 
THR N   H2   sing N N 410 
THR CA  C    sing N N 411 
THR CA  CB   sing N N 412 
THR CA  HA   sing N N 413 
THR C   O    doub N N 414 
THR C   OXT  sing N N 415 
THR CB  OG1  sing N N 416 
THR CB  CG2  sing N N 417 
THR CB  HB   sing N N 418 
THR OG1 HG1  sing N N 419 
THR CG2 HG21 sing N N 420 
THR CG2 HG22 sing N N 421 
THR CG2 HG23 sing N N 422 
THR OXT HXT  sing N N 423 
TRP N   CA   sing N N 424 
TRP N   H    sing N N 425 
TRP N   H2   sing N N 426 
TRP CA  C    sing N N 427 
TRP CA  CB   sing N N 428 
TRP CA  HA   sing N N 429 
TRP C   O    doub N N 430 
TRP C   OXT  sing N N 431 
TRP CB  CG   sing N N 432 
TRP CB  HB2  sing N N 433 
TRP CB  HB3  sing N N 434 
TRP CG  CD1  doub Y N 435 
TRP CG  CD2  sing Y N 436 
TRP CD1 NE1  sing Y N 437 
TRP CD1 HD1  sing N N 438 
TRP CD2 CE2  doub Y N 439 
TRP CD2 CE3  sing Y N 440 
TRP NE1 CE2  sing Y N 441 
TRP NE1 HE1  sing N N 442 
TRP CE2 CZ2  sing Y N 443 
TRP CE3 CZ3  doub Y N 444 
TRP CE3 HE3  sing N N 445 
TRP CZ2 CH2  doub Y N 446 
TRP CZ2 HZ2  sing N N 447 
TRP CZ3 CH2  sing Y N 448 
TRP CZ3 HZ3  sing N N 449 
TRP CH2 HH2  sing N N 450 
TRP OXT HXT  sing N N 451 
TYR N   CA   sing N N 452 
TYR N   H    sing N N 453 
TYR N   H2   sing N N 454 
TYR CA  C    sing N N 455 
TYR CA  CB   sing N N 456 
TYR CA  HA   sing N N 457 
TYR C   O    doub N N 458 
TYR C   OXT  sing N N 459 
TYR CB  CG   sing N N 460 
TYR CB  HB2  sing N N 461 
TYR CB  HB3  sing N N 462 
TYR CG  CD1  doub Y N 463 
TYR CG  CD2  sing Y N 464 
TYR CD1 CE1  sing Y N 465 
TYR CD1 HD1  sing N N 466 
TYR CD2 CE2  doub Y N 467 
TYR CD2 HD2  sing N N 468 
TYR CE1 CZ   doub Y N 469 
TYR CE1 HE1  sing N N 470 
TYR CE2 CZ   sing Y N 471 
TYR CE2 HE2  sing N N 472 
TYR CZ  OH   sing N N 473 
TYR OH  HH   sing N N 474 
TYR OXT HXT  sing N N 475 
VAL N   CA   sing N N 476 
VAL N   H    sing N N 477 
VAL N   H2   sing N N 478 
VAL CA  C    sing N N 479 
VAL CA  CB   sing N N 480 
VAL CA  HA   sing N N 481 
VAL C   O    doub N N 482 
VAL C   OXT  sing N N 483 
VAL CB  CG1  sing N N 484 
VAL CB  CG2  sing N N 485 
VAL CB  HB   sing N N 486 
VAL CG1 HG11 sing N N 487 
VAL CG1 HG12 sing N N 488 
VAL CG1 HG13 sing N N 489 
VAL CG2 HG21 sing N N 490 
VAL CG2 HG22 sing N N 491 
VAL CG2 HG23 sing N N 492 
VAL OXT HXT  sing N N 493 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           75N93021C00015 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
3 GAL 1 n 
3 NAG 2 n 
3 GAL 3 n 
3 SIA 4 n 
4 GLC 1 n 
4 GAL 2 n 
4 NAG 3 n 
4 GAL 4 n 
4 SIA 5 n 
5 NAG 1 n 
5 NAG 2 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5E30 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9DIP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009658 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.001051 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.013376 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007673 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . GLY A 1 4   ? -33.835 -23.468 -100.724 1.00 113.73 ? 10  GLY A N   1 
ATOM   2     C CA  . GLY A 1 4   ? -33.259 -24.575 -99.983  1.00 121.75 ? 10  GLY A CA  1 
ATOM   3     C C   . GLY A 1 4   ? -33.735 -24.654 -98.545  1.00 116.97 ? 10  GLY A C   1 
ATOM   4     O O   . GLY A 1 4   ? -34.748 -24.055 -98.183  1.00 109.53 ? 10  GLY A O   1 
ATOM   5     N N   . ASP A 1 5   ? -32.999 -25.395 -97.725  1.00 123.05 ? 11  ASP A N   1 
ATOM   6     C CA  . ASP A 1 5   ? -33.333 -25.569 -96.320  1.00 115.50 ? 11  ASP A CA  1 
ATOM   7     C C   . ASP A 1 5   ? -32.709 -24.458 -95.477  1.00 113.82 ? 11  ASP A C   1 
ATOM   8     O O   . ASP A 1 5   ? -31.700 -23.855 -95.848  1.00 108.93 ? 11  ASP A O   1 
ATOM   9     C CB  . ASP A 1 5   ? -32.867 -26.939 -95.825  1.00 111.35 ? 11  ASP A CB  1 
ATOM   10    C CG  . ASP A 1 5   ? -33.473 -28.081 -96.619  1.00 108.85 ? 11  ASP A CG  1 
ATOM   11    O OD1 . ASP A 1 5   ? -34.602 -27.918 -97.127  1.00 106.08 ? 11  ASP A OD1 1 
ATOM   12    O OD2 . ASP A 1 5   ? -32.821 -29.140 -96.736  1.00 106.93 ? 11  ASP A OD2 1 
ATOM   13    N N   . GLN A 1 6   ? -33.327 -24.194 -94.326  1.00 111.90 ? 12  GLN A N   1 
ATOM   14    C CA  . GLN A 1 6   ? -32.945 -23.074 -93.477  1.00 109.33 ? 12  GLN A CA  1 
ATOM   15    C C   . GLN A 1 6   ? -32.840 -23.494 -92.019  1.00 107.68 ? 12  GLN A C   1 
ATOM   16    O O   . GLN A 1 6   ? -33.652 -24.283 -91.527  1.00 102.44 ? 12  GLN A O   1 
ATOM   17    C CB  . GLN A 1 6   ? -33.948 -21.922 -93.590  1.00 97.40  ? 12  GLN A CB  1 
ATOM   18    C CG  . GLN A 1 6   ? -33.547 -20.845 -94.573  1.00 111.44 ? 12  GLN A CG  1 
ATOM   19    C CD  . GLN A 1 6   ? -34.541 -19.704 -94.620  1.00 115.62 ? 12  GLN A CD  1 
ATOM   20    O OE1 . GLN A 1 6   ? -35.007 -19.318 -95.692  1.00 116.48 ? 12  GLN A OE1 1 
ATOM   21    N NE2 . GLN A 1 6   ? -34.868 -19.153 -93.456  1.00 99.18  ? 12  GLN A NE2 1 
ATOM   22    N N   . ILE A 1 7   ? -31.839 -22.945 -91.333  1.00 104.62 ? 13  ILE A N   1 
ATOM   23    C CA  . ILE A 1 7   ? -31.712 -23.037 -89.883  1.00 107.64 ? 13  ILE A CA  1 
ATOM   24    C C   . ILE A 1 7   ? -31.458 -21.631 -89.354  1.00 99.80  ? 13  ILE A C   1 
ATOM   25    O O   . ILE A 1 7   ? -30.771 -20.832 -90.000  1.00 96.59  ? 13  ILE A O   1 
ATOM   26    C CB  . ILE A 1 7   ? -30.594 -24.017 -89.459  1.00 92.78  ? 13  ILE A CB  1 
ATOM   27    C CG1 . ILE A 1 7   ? -30.711 -24.350 -87.970  1.00 87.64  ? 13  ILE A CG1 1 
ATOM   28    C CG2 . ILE A 1 7   ? -29.214 -23.460 -89.784  1.00 92.22  ? 13  ILE A CG2 1 
ATOM   29    C CD1 . ILE A 1 7   ? -29.805 -25.477 -87.530  1.00 86.14  ? 13  ILE A CD1 1 
ATOM   30    N N   . CYS A 1 8   ? -32.034 -21.317 -88.195  1.00 103.03 ? 14  CYS A N   1 
ATOM   31    C CA  . CYS A 1 8   ? -32.049 -19.952 -87.689  1.00 107.68 ? 14  CYS A CA  1 
ATOM   32    C C   . CYS A 1 8   ? -31.637 -19.914 -86.223  1.00 103.37 ? 14  CYS A C   1 
ATOM   33    O O   . CYS A 1 8   ? -31.678 -20.922 -85.512  1.00 94.64  ? 14  CYS A O   1 
ATOM   34    C CB  . CYS A 1 8   ? -33.436 -19.310 -87.847  1.00 106.31 ? 14  CYS A CB  1 
ATOM   35    S SG  . CYS A 1 8   ? -34.044 -19.183 -89.548  1.00 108.07 ? 14  CYS A SG  1 
ATOM   36    N N   . ILE A 1 9   ? -31.239 -18.721 -85.781  1.00 109.80 ? 15  ILE A N   1 
ATOM   37    C CA  . ILE A 1 9   ? -30.856 -18.453 -84.400  1.00 107.87 ? 15  ILE A CA  1 
ATOM   38    C C   . ILE A 1 9   ? -31.817 -17.418 -83.830  1.00 100.19 ? 15  ILE A C   1 
ATOM   39    O O   . ILE A 1 9   ? -32.026 -16.360 -84.436  1.00 104.76 ? 15  ILE A O   1 
ATOM   40    C CB  . ILE A 1 9   ? -29.401 -17.959 -84.299  1.00 96.06  ? 15  ILE A CB  1 
ATOM   41    C CG1 . ILE A 1 9   ? -28.433 -19.050 -84.758  1.00 100.41 ? 15  ILE A CG1 1 
ATOM   42    C CG2 . ILE A 1 9   ? -29.081 -17.514 -82.880  1.00 99.55  ? 15  ILE A CG2 1 
ATOM   43    C CD1 . ILE A 1 9   ? -28.559 -20.335 -83.978  1.00 98.30  ? 15  ILE A CD1 1 
ATOM   44    N N   . GLY A 1 10  ? -32.393 -17.719 -82.667  1.00 95.13  ? 16  GLY A N   1 
ATOM   45    C CA  . GLY A 1 10  ? -33.360 -16.840 -82.041  1.00 102.41 ? 16  GLY A CA  1 
ATOM   46    C C   . GLY A 1 10  ? -33.398 -17.048 -80.542  1.00 99.87  ? 16  GLY A C   1 
ATOM   47    O O   . GLY A 1 10  ? -32.667 -17.872 -79.989  1.00 85.69  ? 16  GLY A O   1 
ATOM   48    N N   . TYR A 1 11  ? -34.274 -16.291 -79.882  1.00 100.47 ? 17  TYR A N   1 
ATOM   49    C CA  . TYR A 1 11  ? -34.361 -16.306 -78.429  1.00 91.54  ? 17  TYR A CA  1 
ATOM   50    C C   . TYR A 1 11  ? -35.818 -16.239 -77.987  1.00 100.29 ? 17  TYR A C   1 
ATOM   51    O O   . TYR A 1 11  ? -36.720 -15.919 -78.765  1.00 102.70 ? 17  TYR A O   1 
ATOM   52    C CB  . TYR A 1 11  ? -33.551 -15.160 -77.805  1.00 91.19  ? 17  TYR A CB  1 
ATOM   53    C CG  . TYR A 1 11  ? -33.752 -13.824 -78.478  1.00 90.42  ? 17  TYR A CG  1 
ATOM   54    C CD1 . TYR A 1 11  ? -34.767 -12.969 -78.075  1.00 97.23  ? 17  TYR A CD1 1 
ATOM   55    C CD2 . TYR A 1 11  ? -32.921 -13.416 -79.512  1.00 101.62 ? 17  TYR A CD2 1 
ATOM   56    C CE1 . TYR A 1 11  ? -34.952 -11.745 -78.687  1.00 101.46 ? 17  TYR A CE1 1 
ATOM   57    C CE2 . TYR A 1 11  ? -33.099 -12.197 -80.131  1.00 113.37 ? 17  TYR A CE2 1 
ATOM   58    C CZ  . TYR A 1 11  ? -34.115 -11.364 -79.715  1.00 106.14 ? 17  TYR A CZ  1 
ATOM   59    O OH  . TYR A 1 11  ? -34.296 -10.147 -80.330  1.00 111.65 ? 17  TYR A OH  1 
ATOM   60    N N   . HIS A 1 12  ? -36.025 -16.547 -76.708  1.00 91.78  ? 18  HIS A N   1 
ATOM   61    C CA  . HIS A 1 12  ? -37.354 -16.719 -76.138  1.00 79.87  ? 18  HIS A CA  1 
ATOM   62    C C   . HIS A 1 12  ? -38.128 -15.404 -76.086  1.00 92.01  ? 18  HIS A C   1 
ATOM   63    O O   . HIS A 1 12  ? -37.557 -14.320 -75.933  1.00 102.87 ? 18  HIS A O   1 
ATOM   64    C CB  . HIS A 1 12  ? -37.231 -17.308 -74.730  1.00 87.46  ? 18  HIS A CB  1 
ATOM   65    C CG  . HIS A 1 12  ? -38.540 -17.650 -74.090  1.00 98.62  ? 18  HIS A CG  1 
ATOM   66    N ND1 . HIS A 1 12  ? -39.391 -16.695 -73.576  1.00 103.59 ? 18  HIS A ND1 1 
ATOM   67    C CD2 . HIS A 1 12  ? -39.130 -18.846 -73.854  1.00 104.88 ? 18  HIS A CD2 1 
ATOM   68    C CE1 . HIS A 1 12  ? -40.457 -17.287 -73.067  1.00 104.05 ? 18  HIS A CE1 1 
ATOM   69    N NE2 . HIS A 1 12  ? -40.323 -18.592 -73.221  1.00 104.48 ? 18  HIS A NE2 1 
ATOM   70    N N   . ALA A 1 13  ? -39.450 -15.515 -76.226  1.00 89.29  ? 19  ALA A N   1 
ATOM   71    C CA  . ALA A 1 13  ? -40.381 -14.419 -75.992  1.00 94.57  ? 19  ALA A CA  1 
ATOM   72    C C   . ALA A 1 13  ? -41.661 -14.993 -75.399  1.00 101.81 ? 19  ALA A C   1 
ATOM   73    O O   . ALA A 1 13  ? -42.013 -16.147 -75.659  1.00 102.34 ? 19  ALA A O   1 
ATOM   74    C CB  . ALA A 1 13  ? -40.688 -13.643 -77.279  1.00 91.65  ? 19  ALA A CB  1 
ATOM   75    N N   . ASN A 1 14  ? -42.358 -14.185 -74.602  1.00 100.82 ? 20  ASN A N   1 
ATOM   76    C CA  . ASN A 1 14  ? -43.543 -14.666 -73.894  1.00 92.72  ? 20  ASN A CA  1 
ATOM   77    C C   . ASN A 1 14  ? -44.525 -13.512 -73.707  1.00 89.85  ? 20  ASN A C   1 
ATOM   78    O O   . ASN A 1 14  ? -44.378 -12.440 -74.302  1.00 88.05  ? 20  ASN A O   1 
ATOM   79    C CB  . ASN A 1 14  ? -43.152 -15.302 -72.555  1.00 90.11  ? 20  ASN A CB  1 
ATOM   80    C CG  . ASN A 1 14  ? -42.417 -14.340 -71.646  1.00 96.64  ? 20  ASN A CG  1 
ATOM   81    O OD1 . ASN A 1 14  ? -41.808 -13.376 -72.108  1.00 94.17  ? 20  ASN A OD1 1 
ATOM   82    N ND2 . ASN A 1 14  ? -42.466 -14.599 -70.344  1.00 90.71  ? 20  ASN A ND2 1 
ATOM   83    N N   . ASN A 1 15  ? -45.537 -13.743 -72.870  1.00 101.05 ? 21  ASN A N   1 
ATOM   84    C CA  . ASN A 1 15  ? -46.590 -12.762 -72.601  1.00 103.51 ? 21  ASN A CA  1 
ATOM   85    C C   . ASN A 1 15  ? -46.175 -11.831 -71.460  1.00 102.32 ? 21  ASN A C   1 
ATOM   86    O O   . ASN A 1 15  ? -46.807 -11.753 -70.409  1.00 111.72 ? 21  ASN A O   1 
ATOM   87    C CB  . ASN A 1 15  ? -47.901 -13.477 -72.285  1.00 102.59 ? 21  ASN A CB  1 
ATOM   88    C CG  . ASN A 1 15  ? -47.752 -14.515 -71.179  1.00 103.39 ? 21  ASN A CG  1 
ATOM   89    O OD1 . ASN A 1 15  ? -46.672 -14.690 -70.614  1.00 96.13  ? 21  ASN A OD1 1 
ATOM   90    N ND2 . ASN A 1 15  ? -48.845 -15.201 -70.859  1.00 100.49 ? 21  ASN A ND2 1 
ATOM   91    N N   . SER A 1 16  ? -45.097 -11.094 -71.700  1.00 106.54 ? 22  SER A N   1 
ATOM   92    C CA  . SER A 1 16  ? -44.361 -10.411 -70.644  1.00 95.83  ? 22  SER A CA  1 
ATOM   93    C C   . SER A 1 16  ? -44.510 -8.899  -70.776  1.00 97.68  ? 22  SER A C   1 
ATOM   94    O O   . SER A 1 16  ? -44.173 -8.326  -71.816  1.00 97.75  ? 22  SER A O   1 
ATOM   95    C CB  . SER A 1 16  ? -42.889 -10.814 -70.694  1.00 103.73 ? 22  SER A CB  1 
ATOM   96    O OG  . SER A 1 16  ? -42.220 -10.456 -69.501  1.00 105.64 ? 22  SER A OG  1 
ATOM   97    N N   . THR A 1 17  ? -45.004 -8.260  -69.711  1.00 96.25  ? 23  THR A N   1 
ATOM   98    C CA  . THR A 1 17  ? -45.187 -6.815  -69.633  1.00 99.30  ? 23  THR A CA  1 
ATOM   99    C C   . THR A 1 17  ? -44.283 -6.177  -68.583  1.00 91.75  ? 23  THR A C   1 
ATOM   100   O O   . THR A 1 17  ? -44.545 -5.052  -68.152  1.00 85.28  ? 23  THR A O   1 
ATOM   101   C CB  . THR A 1 17  ? -46.647 -6.476  -69.313  1.00 94.38  ? 23  THR A CB  1 
ATOM   102   O OG1 . THR A 1 17  ? -47.056 -7.181  -68.132  1.00 83.69  ? 23  THR A OG1 1 
ATOM   103   C CG2 . THR A 1 17  ? -47.555 -6.848  -70.463  1.00 89.81  ? 23  THR A CG2 1 
ATOM   104   N N   . GLU A 1 18  ? -43.233 -6.879  -68.162  1.00 91.17  ? 24  GLU A N   1 
ATOM   105   C CA  . GLU A 1 18  ? -42.493 -6.557  -66.946  1.00 83.91  ? 24  GLU A CA  1 
ATOM   106   C C   . GLU A 1 18  ? -41.235 -5.788  -67.309  1.00 76.02  ? 24  GLU A C   1 
ATOM   107   O O   . GLU A 1 18  ? -40.434 -6.239  -68.135  1.00 90.37  ? 24  GLU A O   1 
ATOM   108   C CB  . GLU A 1 18  ? -42.139 -7.821  -66.153  1.00 82.44  ? 24  GLU A CB  1 
ATOM   109   C CG  . GLU A 1 18  ? -43.342 -8.680  -65.772  1.00 96.01  ? 24  GLU A CG  1 
ATOM   110   C CD  . GLU A 1 18  ? -44.056 -9.213  -66.989  1.00 111.22 ? 24  GLU A CD  1 
ATOM   111   O OE1 . GLU A 1 18  ? -43.325 -9.604  -67.917  1.00 101.78 ? 24  GLU A OE1 1 
ATOM   112   O OE2 . GLU A 1 18  ? -45.304 -9.138  -67.061  1.00 105.15 ? 24  GLU A OE2 1 
ATOM   113   N N   . GLN A 1 19  ? -41.059 -4.634  -66.681  1.00 87.21  ? 25  GLN A N   1 
ATOM   114   C CA  . GLN A 1 19  ? -40.062 -3.664  -67.102  1.00 88.99  ? 25  GLN A CA  1 
ATOM   115   C C   . GLN A 1 19  ? -39.002 -3.503  -66.022  1.00 88.91  ? 25  GLN A C   1 
ATOM   116   O O   . GLN A 1 19  ? -39.328 -3.293  -64.849  1.00 81.92  ? 25  GLN A O   1 
ATOM   117   C CB  . GLN A 1 19  ? -40.728 -2.322  -67.410  1.00 85.93  ? 25  GLN A CB  1 
ATOM   118   C CG  . GLN A 1 19  ? -42.176 -2.466  -67.850  1.00 89.83  ? 25  GLN A CG  1 
ATOM   119   C CD  . GLN A 1 19  ? -42.897 -1.141  -67.940  1.00 103.85 ? 25  GLN A CD  1 
ATOM   120   O OE1 . GLN A 1 19  ? -42.385 -0.184  -68.518  1.00 103.59 ? 25  GLN A OE1 1 
ATOM   121   N NE2 . GLN A 1 19  ? -44.092 -1.077  -67.362  1.00 101.63 ? 25  GLN A NE2 1 
ATOM   122   N N   . VAL A 1 20  ? -37.740 -3.612  -66.420  1.00 81.17  ? 26  VAL A N   1 
ATOM   123   C CA  . VAL A 1 20  ? -36.623 -3.231  -65.574  1.00 75.10  ? 26  VAL A CA  1 
ATOM   124   C C   . VAL A 1 20  ? -35.962 -2.010  -66.198  1.00 84.96  ? 26  VAL A C   1 
ATOM   125   O O   . VAL A 1 20  ? -36.237 -1.639  -67.338  1.00 83.51  ? 26  VAL A O   1 
ATOM   126   C CB  . VAL A 1 20  ? -35.607 -4.374  -65.387  1.00 77.04  ? 26  VAL A CB  1 
ATOM   127   C CG1 . VAL A 1 20  ? -36.246 -5.550  -64.674  1.00 69.30  ? 26  VAL A CG1 1 
ATOM   128   C CG2 . VAL A 1 20  ? -35.042 -4.796  -66.727  1.00 77.03  ? 26  VAL A CG2 1 
ATOM   129   N N   . ASP A 1 21  ? -35.087 -1.374  -65.430  1.00 80.04  ? 27  ASP A N   1 
ATOM   130   C CA  . ASP A 1 21  ? -34.284 -0.272  -65.931  1.00 74.96  ? 27  ASP A CA  1 
ATOM   131   C C   . ASP A 1 21  ? -32.814 -0.656  -65.874  1.00 79.10  ? 27  ASP A C   1 
ATOM   132   O O   . ASP A 1 21  ? -32.383 -1.397  -64.985  1.00 82.80  ? 27  ASP A O   1 
ATOM   133   C CB  . ASP A 1 21  ? -34.516 1.021   -65.133  1.00 79.60  ? 27  ASP A CB  1 
ATOM   134   C CG  . ASP A 1 21  ? -35.971 1.472   -65.143  1.00 95.31  ? 27  ASP A CG  1 
ATOM   135   O OD1 . ASP A 1 21  ? -36.258 2.550   -64.579  1.00 94.48  ? 27  ASP A OD1 1 
ATOM   136   O OD2 . ASP A 1 21  ? -36.829 0.752   -65.694  1.00 97.11  ? 27  ASP A OD2 1 
ATOM   137   N N   . THR A 1 22  ? -32.052 -0.160  -66.839  1.00 76.05  ? 28  THR A N   1 
ATOM   138   C CA  . THR A 1 22  ? -30.610 -0.334  -66.881  1.00 72.37  ? 28  THR A CA  1 
ATOM   139   C C   . THR A 1 22  ? -29.940 1.022   -66.698  1.00 80.40  ? 28  THR A C   1 
ATOM   140   O O   . THR A 1 22  ? -30.600 2.060   -66.589  1.00 70.14  ? 28  THR A O   1 
ATOM   141   C CB  . THR A 1 22  ? -30.176 -0.993  -68.193  1.00 88.61  ? 28  THR A CB  1 
ATOM   142   O OG1 . THR A 1 22  ? -30.404 -0.092  -69.285  1.00 79.71  ? 28  THR A OG1 1 
ATOM   143   C CG2 . THR A 1 22  ? -30.955 -2.277  -68.430  1.00 82.30  ? 28  THR A CG2 1 
ATOM   144   N N   . ILE A 1 23  ? -28.606 1.007   -66.660  1.00 77.86  ? 29  ILE A N   1 
ATOM   145   C CA  . ILE A 1 23  ? -27.879 2.261   -66.512  1.00 81.02  ? 29  ILE A CA  1 
ATOM   146   C C   . ILE A 1 23  ? -28.026 3.118   -67.764  1.00 81.77  ? 29  ILE A C   1 
ATOM   147   O O   . ILE A 1 23  ? -28.012 4.352   -67.683  1.00 87.12  ? 29  ILE A O   1 
ATOM   148   C CB  . ILE A 1 23  ? -26.401 1.991   -66.164  1.00 82.87  ? 29  ILE A CB  1 
ATOM   149   C CG1 . ILE A 1 23  ? -25.712 3.280   -65.716  1.00 84.27  ? 29  ILE A CG1 1 
ATOM   150   C CG2 . ILE A 1 23  ? -25.661 1.381   -67.340  1.00 86.28  ? 29  ILE A CG2 1 
ATOM   151   C CD1 . ILE A 1 23  ? -26.339 3.907   -64.492  1.00 84.75  ? 29  ILE A CD1 1 
ATOM   152   N N   . MET A 1 24  ? -28.197 2.495   -68.932  1.00 85.24  ? 30  MET A N   1 
ATOM   153   C CA  . MET A 1 24  ? -28.304 3.228   -70.185  1.00 95.13  ? 30  MET A CA  1 
ATOM   154   C C   . MET A 1 24  ? -29.711 3.256   -70.766  1.00 87.49  ? 30  MET A C   1 
ATOM   155   O O   . MET A 1 24  ? -29.960 4.039   -71.690  1.00 83.87  ? 30  MET A O   1 
ATOM   156   C CB  . MET A 1 24  ? -27.338 2.646   -71.229  1.00 91.18  ? 30  MET A CB  1 
ATOM   157   C CG  . MET A 1 24  ? -25.871 2.811   -70.862  1.00 92.74  ? 30  MET A CG  1 
ATOM   158   S SD  . MET A 1 24  ? -24.758 2.770   -72.281  1.00 107.16 ? 30  MET A SD  1 
ATOM   159   C CE  . MET A 1 24  ? -24.866 1.050   -72.767  1.00 87.42  ? 30  MET A CE  1 
ATOM   160   N N   . GLU A 1 25  ? -30.635 2.439   -70.261  1.00 85.25  ? 31  GLU A N   1 
ATOM   161   C CA  . GLU A 1 25  ? -31.993 2.401   -70.785  1.00 88.72  ? 31  GLU A CA  1 
ATOM   162   C C   . GLU A 1 25  ? -32.988 2.231   -69.646  1.00 82.00  ? 31  GLU A C   1 
ATOM   163   O O   . GLU A 1 25  ? -32.659 1.697   -68.585  1.00 87.38  ? 31  GLU A O   1 
ATOM   164   C CB  . GLU A 1 25  ? -32.165 1.276   -71.815  1.00 92.47  ? 31  GLU A CB  1 
ATOM   165   C CG  . GLU A 1 25  ? -31.611 1.622   -73.189  1.00 102.21 ? 31  GLU A CG  1 
ATOM   166   C CD  . GLU A 1 25  ? -30.778 0.506   -73.790  1.00 113.59 ? 31  GLU A CD  1 
ATOM   167   O OE1 . GLU A 1 25  ? -31.121 -0.676  -73.579  1.00 100.16 ? 31  GLU A OE1 1 
ATOM   168   O OE2 . GLU A 1 25  ? -29.774 0.815   -74.467  1.00 112.74 ? 31  GLU A OE2 1 
ATOM   169   N N   . LYS A 1 26  ? -34.214 2.692   -69.886  1.00 81.75  ? 32  LYS A N   1 
ATOM   170   C CA  . LYS A 1 26  ? -35.291 2.634   -68.910  1.00 91.14  ? 32  LYS A CA  1 
ATOM   171   C C   . LYS A 1 26  ? -36.537 2.049   -69.562  1.00 99.51  ? 32  LYS A C   1 
ATOM   172   O O   . LYS A 1 26  ? -36.714 2.118   -70.782  1.00 97.85  ? 32  LYS A O   1 
ATOM   173   C CB  . LYS A 1 26  ? -35.597 4.025   -68.328  1.00 93.20  ? 32  LYS A CB  1 
ATOM   174   C CG  . LYS A 1 26  ? -34.407 4.673   -67.631  1.00 95.52  ? 32  LYS A CG  1 
ATOM   175   C CD  . LYS A 1 26  ? -34.622 6.160   -67.372  1.00 92.16  ? 32  LYS A CD  1 
ATOM   176   C CE  . LYS A 1 26  ? -35.535 6.407   -66.184  1.00 77.70  ? 32  LYS A CE  1 
ATOM   177   N NZ  . LYS A 1 26  ? -35.537 7.845   -65.789  1.00 83.75  ? 32  LYS A NZ  1 
ATOM   178   N N   . ASN A 1 27  ? -37.401 1.467   -68.726  1.00 97.12  ? 33  ASN A N   1 
ATOM   179   C CA  . ASN A 1 27  ? -38.656 0.853   -69.170  1.00 91.31  ? 33  ASN A CA  1 
ATOM   180   C C   . ASN A 1 27  ? -38.407 -0.216  -70.235  1.00 91.02  ? 33  ASN A C   1 
ATOM   181   O O   . ASN A 1 27  ? -39.089 -0.279  -71.260  1.00 83.96  ? 33  ASN A O   1 
ATOM   182   C CB  . ASN A 1 27  ? -39.640 1.914   -69.674  1.00 80.33  ? 33  ASN A CB  1 
ATOM   183   C CG  . ASN A 1 27  ? -40.260 2.718   -68.547  1.00 93.17  ? 33  ASN A CG  1 
ATOM   184   O OD1 . ASN A 1 27  ? -39.893 2.562   -67.383  1.00 104.02 ? 33  ASN A OD1 1 
ATOM   185   N ND2 . ASN A 1 27  ? -41.205 3.587   -68.890  1.00 94.14  ? 33  ASN A ND2 1 
ATOM   186   N N   . VAL A 1 28  ? -37.417 -1.066  -69.981  1.00 90.15  ? 34  VAL A N   1 
ATOM   187   C CA  . VAL A 1 28  ? -37.077 -2.163  -70.882  1.00 80.75  ? 34  VAL A CA  1 
ATOM   188   C C   . VAL A 1 28  ? -37.858 -3.401  -70.459  1.00 84.08  ? 34  VAL A C   1 
ATOM   189   O O   . VAL A 1 28  ? -37.669 -3.916  -69.351  1.00 87.90  ? 34  VAL A O   1 
ATOM   190   C CB  . VAL A 1 28  ? -35.566 -2.437  -70.880  1.00 79.42  ? 34  VAL A CB  1 
ATOM   191   C CG1 . VAL A 1 28  ? -35.263 -3.739  -71.606  1.00 72.76  ? 34  VAL A CG1 1 
ATOM   192   C CG2 . VAL A 1 28  ? -34.817 -1.279  -71.518  1.00 71.69  ? 34  VAL A CG2 1 
ATOM   193   N N   . THR A 1 29  ? -38.729 -3.883  -71.342  1.00 82.40  ? 35  THR A N   1 
ATOM   194   C CA  . THR A 1 29  ? -39.539 -5.058  -71.052  1.00 79.19  ? 35  THR A CA  1 
ATOM   195   C C   . THR A 1 29  ? -38.703 -6.324  -71.203  1.00 79.41  ? 35  THR A C   1 
ATOM   196   O O   . THR A 1 29  ? -37.979 -6.486  -72.190  1.00 80.80  ? 35  THR A O   1 
ATOM   197   C CB  . THR A 1 29  ? -40.755 -5.110  -71.977  1.00 79.28  ? 35  THR A CB  1 
ATOM   198   O OG1 . THR A 1 29  ? -41.498 -3.890  -71.859  1.00 85.40  ? 35  THR A OG1 1 
ATOM   199   C CG2 . THR A 1 29  ? -41.656 -6.278  -71.611  1.00 72.59  ? 35  THR A CG2 1 
ATOM   200   N N   . VAL A 1 30  ? -38.800 -7.220  -70.219  1.00 75.15  ? 36  VAL A N   1 
ATOM   201   C CA  . VAL A 1 30  ? -38.043 -8.464  -70.202  1.00 75.69  ? 36  VAL A CA  1 
ATOM   202   C C   . VAL A 1 30  ? -39.006 -9.623  -69.978  1.00 79.50  ? 36  VAL A C   1 
ATOM   203   O O   . VAL A 1 30  ? -40.174 -9.436  -69.636  1.00 83.81  ? 36  VAL A O   1 
ATOM   204   C CB  . VAL A 1 30  ? -36.940 -8.471  -69.124  1.00 88.70  ? 36  VAL A CB  1 
ATOM   205   C CG1 . VAL A 1 30  ? -36.163 -7.167  -69.147  1.00 82.29  ? 36  VAL A CG1 1 
ATOM   206   C CG2 . VAL A 1 30  ? -37.541 -8.722  -67.750  1.00 72.74  ? 36  VAL A CG2 1 
ATOM   207   N N   . THR A 1 31  ? -38.490 -10.839 -70.170  1.00 80.51  ? 37  THR A N   1 
ATOM   208   C CA  . THR A 1 31  ? -39.318 -12.032 -70.026  1.00 84.32  ? 37  THR A CA  1 
ATOM   209   C C   . THR A 1 31  ? -39.482 -12.426 -68.561  1.00 91.22  ? 37  THR A C   1 
ATOM   210   O O   . THR A 1 31  ? -40.597 -12.706 -68.109  1.00 95.28  ? 37  THR A O   1 
ATOM   211   C CB  . THR A 1 31  ? -38.717 -13.190 -70.828  1.00 82.22  ? 37  THR A CB  1 
ATOM   212   O OG1 . THR A 1 31  ? -37.483 -13.601 -70.229  1.00 91.04  ? 37  THR A OG1 1 
ATOM   213   C CG2 . THR A 1 31  ? -38.453 -12.764 -72.263  1.00 81.83  ? 37  THR A CG2 1 
ATOM   214   N N   . HIS A 1 32  ? -38.382 -12.461 -67.809  1.00 95.76  ? 38  HIS A N   1 
ATOM   215   C CA  . HIS A 1 32  ? -38.393 -12.854 -66.406  1.00 91.30  ? 38  HIS A CA  1 
ATOM   216   C C   . HIS A 1 32  ? -37.681 -11.794 -65.579  1.00 92.56  ? 38  HIS A C   1 
ATOM   217   O O   . HIS A 1 32  ? -36.673 -11.229 -66.016  1.00 91.63  ? 38  HIS A O   1 
ATOM   218   C CB  . HIS A 1 32  ? -37.708 -14.216 -66.190  1.00 80.71  ? 38  HIS A CB  1 
ATOM   219   C CG  . HIS A 1 32  ? -38.342 -15.348 -66.940  1.00 105.08 ? 38  HIS A CG  1 
ATOM   220   N ND1 . HIS A 1 32  ? -38.556 -15.317 -68.301  1.00 99.94  ? 38  HIS A ND1 1 
ATOM   221   C CD2 . HIS A 1 32  ? -38.791 -16.555 -66.518  1.00 100.18 ? 38  HIS A CD2 1 
ATOM   222   C CE1 . HIS A 1 32  ? -39.120 -16.449 -68.684  1.00 98.24  ? 38  HIS A CE1 1 
ATOM   223   N NE2 . HIS A 1 32  ? -39.272 -17.218 -67.621  1.00 101.56 ? 38  HIS A NE2 1 
ATOM   224   N N   . ALA A 1 33  ? -38.194 -11.538 -64.378  1.00 90.68  ? 39  ALA A N   1 
ATOM   225   C CA  . ALA A 1 33  ? -37.608 -10.535 -63.501  1.00 87.25  ? 39  ALA A CA  1 
ATOM   226   C C   . ALA A 1 33  ? -37.894 -10.905 -62.054  1.00 91.42  ? 39  ALA A C   1 
ATOM   227   O O   . ALA A 1 33  ? -38.753 -11.742 -61.764  1.00 85.71  ? 39  ALA A O   1 
ATOM   228   C CB  . ALA A 1 33  ? -38.137 -9.132  -63.816  1.00 67.75  ? 39  ALA A CB  1 
ATOM   229   N N   . GLN A 1 34  ? -37.156 -10.272 -61.143  1.00 88.79  ? 40  GLN A N   1 
ATOM   230   C CA  . GLN A 1 34  ? -37.310 -10.536 -59.719  1.00 78.80  ? 40  GLN A CA  1 
ATOM   231   C C   . GLN A 1 34  ? -37.040 -9.266  -58.927  1.00 79.11  ? 40  GLN A C   1 
ATOM   232   O O   . GLN A 1 34  ? -36.078 -8.544  -59.203  1.00 84.52  ? 40  GLN A O   1 
ATOM   233   C CB  . GLN A 1 34  ? -36.371 -11.656 -59.257  1.00 76.00  ? 40  GLN A CB  1 
ATOM   234   C CG  . GLN A 1 34  ? -36.492 -11.984 -57.778  1.00 77.58  ? 40  GLN A CG  1 
ATOM   235   C CD  . GLN A 1 34  ? -36.297 -13.457 -57.491  1.00 74.29  ? 40  GLN A CD  1 
ATOM   236   O OE1 . GLN A 1 34  ? -35.627 -14.166 -58.242  1.00 87.73  ? 40  GLN A OE1 1 
ATOM   237   N NE2 . GLN A 1 34  ? -36.894 -13.930 -56.403  1.00 88.21  ? 40  GLN A NE2 1 
ATOM   238   N N   . ASP A 1 35  ? -37.894 -9.006  -57.940  1.00 77.38  ? 41  ASP A N   1 
ATOM   239   C CA  . ASP A 1 35  ? -37.727 -7.873  -57.041  1.00 84.63  ? 41  ASP A CA  1 
ATOM   240   C C   . ASP A 1 35  ? -36.995 -8.324  -55.784  1.00 75.05  ? 41  ASP A C   1 
ATOM   241   O O   . ASP A 1 35  ? -37.304 -9.375  -55.215  1.00 75.29  ? 41  ASP A O   1 
ATOM   242   C CB  . ASP A 1 35  ? -39.088 -7.273  -56.675  1.00 84.32  ? 41  ASP A CB  1 
ATOM   243   C CG  . ASP A 1 35  ? -38.990 -5.834  -56.194  1.00 81.03  ? 41  ASP A CG  1 
ATOM   244   O OD1 . ASP A 1 35  ? -37.931 -5.445  -55.660  1.00 83.85  ? 41  ASP A OD1 1 
ATOM   245   O OD2 . ASP A 1 35  ? -39.980 -5.090  -56.350  1.00 78.84  ? 41  ASP A OD2 1 
ATOM   246   N N   . ILE A 1 36  ? -36.013 -7.530  -55.360  1.00 72.02  ? 42  ILE A N   1 
ATOM   247   C CA  . ILE A 1 36  ? -35.226 -7.829  -54.169  1.00 79.32  ? 42  ILE A CA  1 
ATOM   248   C C   . ILE A 1 36  ? -35.551 -6.880  -53.023  1.00 76.01  ? 42  ILE A C   1 
ATOM   249   O O   . ILE A 1 36  ? -34.817 -6.839  -52.029  1.00 70.23  ? 42  ILE A O   1 
ATOM   250   C CB  . ILE A 1 36  ? -33.719 -7.819  -54.477  1.00 65.16  ? 42  ILE A CB  1 
ATOM   251   C CG1 . ILE A 1 36  ? -33.267 -6.417  -54.892  1.00 61.42  ? 42  ILE A CG1 1 
ATOM   252   C CG2 . ILE A 1 36  ? -33.392 -8.832  -55.562  1.00 72.73  ? 42  ILE A CG2 1 
ATOM   253   C CD1 . ILE A 1 36  ? -31.821 -6.350  -55.344  1.00 60.72  ? 42  ILE A CD1 1 
ATOM   254   N N   . LEU A 1 37  ? -36.637 -6.119  -53.131  1.00 64.53  ? 43  LEU A N   1 
ATOM   255   C CA  . LEU A 1 37  ? -37.042 -5.158  -52.113  1.00 63.91  ? 43  LEU A CA  1 
ATOM   256   C C   . LEU A 1 37  ? -38.257 -5.698  -51.374  1.00 69.86  ? 43  LEU A C   1 
ATOM   257   O O   . LEU A 1 37  ? -39.326 -5.867  -51.971  1.00 70.14  ? 43  LEU A O   1 
ATOM   258   C CB  . LEU A 1 37  ? -37.363 -3.802  -52.738  1.00 61.85  ? 43  LEU A CB  1 
ATOM   259   C CG  . LEU A 1 37  ? -37.927 -2.765  -51.768  1.00 63.02  ? 43  LEU A CG  1 
ATOM   260   C CD1 . LEU A 1 37  ? -36.827 -2.217  -50.881  1.00 58.82  ? 43  LEU A CD1 1 
ATOM   261   C CD2 . LEU A 1 37  ? -38.622 -1.651  -52.520  1.00 69.13  ? 43  LEU A CD2 1 
ATOM   262   N N   . GLU A 1 38  ? -38.096 -5.957  -50.079  1.00 71.97  ? 44  GLU A N   1 
ATOM   263   C CA  . GLU A 1 38  ? -39.194 -6.445  -49.257  1.00 69.03  ? 44  GLU A CA  1 
ATOM   264   C C   . GLU A 1 38  ? -40.157 -5.307  -48.940  1.00 65.43  ? 44  GLU A C   1 
ATOM   265   O O   . GLU A 1 38  ? -39.741 -4.238  -48.481  1.00 59.18  ? 44  GLU A O   1 
ATOM   266   C CB  . GLU A 1 38  ? -38.656 -7.061  -47.966  1.00 62.93  ? 44  GLU A CB  1 
ATOM   267   C CG  . GLU A 1 38  ? -39.714 -7.728  -47.106  1.00 69.04  ? 44  GLU A CG  1 
ATOM   268   C CD  . GLU A 1 38  ? -40.388 -8.888  -47.813  1.00 81.34  ? 44  GLU A CD  1 
ATOM   269   O OE1 . GLU A 1 38  ? -41.636 -8.943  -47.816  1.00 74.47  ? 44  GLU A OE1 1 
ATOM   270   O OE2 . GLU A 1 38  ? -39.669 -9.742  -48.374  1.00 86.57  ? 44  GLU A OE2 1 
ATOM   271   N N   . LYS A 1 39  ? -41.447 -5.539  -49.187  1.00 66.86  ? 45  LYS A N   1 
ATOM   272   C CA  . LYS A 1 39  ? -42.472 -4.536  -48.940  1.00 70.86  ? 45  LYS A CA  1 
ATOM   273   C C   . LYS A 1 39  ? -43.607 -5.029  -48.055  1.00 59.48  ? 45  LYS A C   1 
ATOM   274   O O   . LYS A 1 39  ? -44.486 -4.233  -47.707  1.00 63.97  ? 45  LYS A O   1 
ATOM   275   C CB  . LYS A 1 39  ? -43.066 -4.036  -50.267  1.00 70.60  ? 45  LYS A CB  1 
ATOM   276   C CG  . LYS A 1 39  ? -42.110 -3.235  -51.133  1.00 73.52  ? 45  LYS A CG  1 
ATOM   277   C CD  . LYS A 1 39  ? -42.791 -2.751  -52.407  1.00 77.84  ? 45  LYS A CD  1 
ATOM   278   C CE  . LYS A 1 39  ? -42.559 -3.705  -53.573  1.00 90.84  ? 45  LYS A CE  1 
ATOM   279   N NZ  . LYS A 1 39  ? -43.125 -5.063  -53.340  1.00 94.92  ? 45  LYS A NZ  1 
ATOM   280   N N   . THR A 1 40  ? -43.613 -6.302  -47.673  1.00 55.81  ? 46  THR A N   1 
ATOM   281   C CA  . THR A 1 40  ? -44.770 -6.924  -47.048  1.00 74.51  ? 46  THR A CA  1 
ATOM   282   C C   . THR A 1 40  ? -44.450 -7.359  -45.625  1.00 77.02  ? 46  THR A C   1 
ATOM   283   O O   . THR A 1 40  ? -43.375 -7.905  -45.353  1.00 65.48  ? 46  THR A O   1 
ATOM   284   C CB  . THR A 1 40  ? -45.252 -8.126  -47.870  1.00 84.12  ? 46  THR A CB  1 
ATOM   285   O OG1 . THR A 1 40  ? -44.143 -8.986  -48.159  1.00 85.09  ? 46  THR A OG1 1 
ATOM   286   C CG2 . THR A 1 40  ? -45.875 -7.655  -49.178  1.00 60.87  ? 46  THR A CG2 1 
ATOM   287   N N   . HIS A 1 41  ? -45.399 -7.111  -44.724  1.00 65.48  ? 47  HIS A N   1 
ATOM   288   C CA  . HIS A 1 41  ? -45.297 -7.495  -43.325  1.00 74.91  ? 47  HIS A CA  1 
ATOM   289   C C   . HIS A 1 41  ? -46.639 -8.057  -42.877  1.00 78.80  ? 47  HIS A C   1 
ATOM   290   O O   . HIS A 1 41  ? -47.677 -7.792  -43.488  1.00 65.49  ? 47  HIS A O   1 
ATOM   291   C CB  . HIS A 1 41  ? -44.887 -6.305  -42.447  1.00 65.57  ? 47  HIS A CB  1 
ATOM   292   C CG  . HIS A 1 41  ? -45.824 -5.141  -42.534  1.00 53.94  ? 47  HIS A CG  1 
ATOM   293   N ND1 . HIS A 1 41  ? -46.979 -5.058  -41.787  1.00 64.68  ? 47  HIS A ND1 1 
ATOM   294   C CD2 . HIS A 1 41  ? -45.777 -4.012  -43.281  1.00 57.98  ? 47  HIS A CD2 1 
ATOM   295   C CE1 . HIS A 1 41  ? -47.603 -3.928  -42.068  1.00 54.05  ? 47  HIS A CE1 1 
ATOM   296   N NE2 . HIS A 1 41  ? -46.895 -3.275  -42.972  1.00 58.80  ? 47  HIS A NE2 1 
ATOM   297   N N   . ASN A 1 42  ? -46.614 -8.846  -41.799  1.00 70.75  ? 48  ASN A N   1 
ATOM   298   C CA  . ASN A 1 42  ? -47.839 -9.488  -41.334  1.00 65.54  ? 48  ASN A CA  1 
ATOM   299   C C   . ASN A 1 42  ? -48.760 -8.543  -40.572  1.00 59.39  ? 48  ASN A C   1 
ATOM   300   O O   . ASN A 1 42  ? -49.892 -8.930  -40.260  1.00 74.67  ? 48  ASN A O   1 
ATOM   301   C CB  . ASN A 1 42  ? -47.514 -10.712 -40.467  1.00 56.78  ? 48  ASN A CB  1 
ATOM   302   C CG  . ASN A 1 42  ? -46.807 -10.355 -39.168  1.00 78.16  ? 48  ASN A CG  1 
ATOM   303   O OD1 . ASN A 1 42  ? -46.565 -9.186  -38.867  1.00 66.37  ? 48  ASN A OD1 1 
ATOM   304   N ND2 . ASN A 1 42  ? -46.478 -11.377 -38.384  1.00 58.24  ? 48  ASN A ND2 1 
ATOM   305   N N   . GLY A 1 43  ? -48.309 -7.330  -40.263  1.00 65.80  ? 49  GLY A N   1 
ATOM   306   C CA  . GLY A 1 43  ? -49.157 -6.361  -39.598  1.00 65.73  ? 49  GLY A CA  1 
ATOM   307   C C   . GLY A 1 43  ? -49.367 -6.587  -38.120  1.00 64.83  ? 49  GLY A C   1 
ATOM   308   O O   . GLY A 1 43  ? -50.273 -5.980  -37.541  1.00 67.98  ? 49  GLY A O   1 
ATOM   309   N N   . LYS A 1 44  ? -48.556 -7.432  -37.485  1.00 63.94  ? 50  LYS A N   1 
ATOM   310   C CA  . LYS A 1 44  ? -48.722 -7.770  -36.080  1.00 68.43  ? 50  LYS A CA  1 
ATOM   311   C C   . LYS A 1 44  ? -47.407 -7.598  -35.329  1.00 68.11  ? 50  LYS A C   1 
ATOM   312   O O   . LYS A 1 44  ? -46.331 -7.508  -35.924  1.00 67.92  ? 50  LYS A O   1 
ATOM   313   C CB  . LYS A 1 44  ? -49.229 -9.209  -35.905  1.00 70.37  ? 50  LYS A CB  1 
ATOM   314   C CG  . LYS A 1 44  ? -50.667 -9.407  -36.331  1.00 70.92  ? 50  LYS A CG  1 
ATOM   315   C CD  . LYS A 1 44  ? -51.536 -8.287  -35.791  1.00 84.85  ? 50  LYS A CD  1 
ATOM   316   C CE  . LYS A 1 44  ? -52.830 -8.819  -35.215  1.00 89.08  ? 50  LYS A CE  1 
ATOM   317   N NZ  . LYS A 1 44  ? -54.014 -8.271  -35.930  1.00 92.66  ? 50  LYS A NZ  1 
ATOM   318   N N   . LEU A 1 45  ? -47.517 -7.543  -34.001  1.00 62.86  ? 51  LEU A N   1 
ATOM   319   C CA  . LEU A 1 45  ? -46.362 -7.625  -33.117  1.00 61.01  ? 51  LEU A CA  1 
ATOM   320   C C   . LEU A 1 45  ? -46.176 -9.078  -32.698  1.00 63.57  ? 51  LEU A C   1 
ATOM   321   O O   . LEU A 1 45  ? -47.116 -9.711  -32.206  1.00 74.56  ? 51  LEU A O   1 
ATOM   322   C CB  . LEU A 1 45  ? -46.544 -6.742  -31.879  1.00 59.87  ? 51  LEU A CB  1 
ATOM   323   C CG  . LEU A 1 45  ? -46.704 -5.226  -32.024  1.00 49.31  ? 51  LEU A CG  1 
ATOM   324   C CD1 . LEU A 1 45  ? -46.922 -4.592  -30.660  1.00 64.72  ? 51  LEU A CD1 1 
ATOM   325   C CD2 . LEU A 1 45  ? -45.496 -4.604  -32.703  1.00 60.62  ? 51  LEU A CD2 1 
ATOM   326   N N   . CYS A 1 46  ? -44.971 -9.603  -32.890  1.00 68.08  ? 52  CYS A N   1 
ATOM   327   C CA  . CYS A 1 46  ? -44.695 -11.011 -32.655  1.00 65.68  ? 52  CYS A CA  1 
ATOM   328   C C   . CYS A 1 46  ? -43.599 -11.176 -31.612  1.00 70.62  ? 52  CYS A C   1 
ATOM   329   O O   . CYS A 1 46  ? -42.959 -10.212 -31.183  1.00 71.95  ? 52  CYS A O   1 
ATOM   330   C CB  . CYS A 1 46  ? -44.281 -11.717 -33.953  1.00 70.12  ? 52  CYS A CB  1 
ATOM   331   S SG  . CYS A 1 46  ? -45.422 -11.510 -35.335  1.00 82.78  ? 52  CYS A SG  1 
ATOM   332   N N   . ASP A 1 47  ? -43.396 -12.425 -31.203  1.00 64.80  ? 53  ASP A N   1 
ATOM   333   C CA  . ASP A 1 47  ? -42.241 -12.768 -30.391  1.00 68.72  ? 53  ASP A CA  1 
ATOM   334   C C   . ASP A 1 47  ? -40.964 -12.555 -31.193  1.00 72.08  ? 53  ASP A C   1 
ATOM   335   O O   . ASP A 1 47  ? -40.959 -12.628 -32.425  1.00 68.70  ? 53  ASP A O   1 
ATOM   336   C CB  . ASP A 1 47  ? -42.319 -14.223 -29.922  1.00 66.76  ? 53  ASP A CB  1 
ATOM   337   C CG  . ASP A 1 47  ? -43.528 -14.494 -29.051  1.00 77.33  ? 53  ASP A CG  1 
ATOM   338   O OD1 . ASP A 1 47  ? -44.288 -13.543 -28.774  1.00 79.89  ? 53  ASP A OD1 1 
ATOM   339   O OD2 . ASP A 1 47  ? -43.717 -15.660 -28.644  1.00 80.01  ? 53  ASP A OD2 1 
ATOM   340   N N   . LEU A 1 48  ? -39.876 -12.284 -30.484  1.00 64.53  ? 54  LEU A N   1 
ATOM   341   C CA  . LEU A 1 48  ? -38.571 -12.084 -31.104  1.00 58.80  ? 54  LEU A CA  1 
ATOM   342   C C   . LEU A 1 48  ? -37.697 -13.279 -30.742  1.00 59.75  ? 54  LEU A C   1 
ATOM   343   O O   . LEU A 1 48  ? -37.192 -13.374 -29.620  1.00 71.60  ? 54  LEU A O   1 
ATOM   344   C CB  . LEU A 1 48  ? -37.945 -10.769 -30.656  1.00 63.92  ? 54  LEU A CB  1 
ATOM   345   C CG  . LEU A 1 48  ? -36.757 -10.289 -31.490  1.00 68.94  ? 54  LEU A CG  1 
ATOM   346   C CD1 . LEU A 1 48  ? -37.171 -10.094 -32.941  1.00 61.36  ? 54  LEU A CD1 1 
ATOM   347   C CD2 . LEU A 1 48  ? -36.186 -9.006  -30.912  1.00 66.96  ? 54  LEU A CD2 1 
ATOM   348   N N   . ASN A 1 49  ? -37.520 -14.186 -31.706  1.00 69.44  ? 55  ASN A N   1 
ATOM   349   C CA  . ASN A 1 49  ? -36.718 -15.399 -31.528  1.00 75.94  ? 55  ASN A CA  1 
ATOM   350   C C   . ASN A 1 49  ? -37.214 -16.222 -30.339  1.00 73.08  ? 55  ASN A C   1 
ATOM   351   O O   . ASN A 1 49  ? -36.435 -16.705 -29.512  1.00 66.38  ? 55  ASN A O   1 
ATOM   352   C CB  . ASN A 1 49  ? -35.232 -15.058 -31.388  1.00 65.07  ? 55  ASN A CB  1 
ATOM   353   C CG  . ASN A 1 49  ? -34.662 -14.410 -32.637  1.00 76.43  ? 55  ASN A CG  1 
ATOM   354   O OD1 . ASN A 1 49  ? -34.637 -13.185 -32.758  1.00 85.19  ? 55  ASN A OD1 1 
ATOM   355   N ND2 . ASN A 1 49  ? -34.207 -15.232 -33.577  1.00 81.87  ? 55  ASN A ND2 1 
ATOM   356   N N   . GLY A 1 50  A -38.533 -16.379 -30.258  1.00 73.10  ? 55  GLY A N   1 
ATOM   357   C CA  . GLY A 1 50  A -39.149 -17.231 -29.265  1.00 62.81  ? 55  GLY A CA  1 
ATOM   358   C C   . GLY A 1 50  A -39.508 -16.565 -27.955  1.00 74.83  ? 55  GLY A C   1 
ATOM   359   O O   . GLY A 1 50  A -40.106 -17.223 -27.092  1.00 64.67  ? 55  GLY A O   1 
ATOM   360   N N   . VAL A 1 51  ? -39.172 -15.291 -27.770  1.00 65.22  ? 56  VAL A N   1 
ATOM   361   C CA  . VAL A 1 51  ? -39.415 -14.587 -26.516  1.00 59.01  ? 56  VAL A CA  1 
ATOM   362   C C   . VAL A 1 51  ? -40.465 -13.509 -26.746  1.00 64.97  ? 56  VAL A C   1 
ATOM   363   O O   . VAL A 1 51  ? -40.335 -12.681 -27.656  1.00 65.24  ? 56  VAL A O   1 
ATOM   364   C CB  . VAL A 1 51  ? -38.121 -13.988 -25.940  1.00 69.99  ? 56  VAL A CB  1 
ATOM   365   C CG1 . VAL A 1 51  ? -38.420 -13.238 -24.653  1.00 58.08  ? 56  VAL A CG1 1 
ATOM   366   C CG2 . VAL A 1 51  ? -37.106 -15.087 -25.685  1.00 54.04  ? 56  VAL A CG2 1 
ATOM   367   N N   . LYS A 1 52  ? -41.502 -13.527 -25.915  1.00 66.28  ? 57  LYS A N   1 
ATOM   368   C CA  . LYS A 1 52  ? -42.612 -12.600 -26.033  1.00 66.09  ? 57  LYS A CA  1 
ATOM   369   C C   . LYS A 1 52  ? -42.178 -11.191 -25.627  1.00 67.54  ? 57  LYS A C   1 
ATOM   370   O O   . LYS A 1 52  ? -41.348 -11.024 -24.731  1.00 61.21  ? 57  LYS A O   1 
ATOM   371   C CB  . LYS A 1 52  ? -43.775 -13.051 -25.146  1.00 70.72  ? 57  LYS A CB  1 
ATOM   372   C CG  . LYS A 1 52  ? -44.141 -14.542 -25.231  1.00 79.85  ? 57  LYS A CG  1 
ATOM   373   C CD  . LYS A 1 52  ? -43.260 -15.447 -24.352  1.00 86.72  ? 57  LYS A CD  1 
ATOM   374   C CE  . LYS A 1 52  ? -43.300 -15.060 -22.879  1.00 98.20  ? 57  LYS A CE  1 
ATOM   375   N NZ  . LYS A 1 52  ? -42.485 -15.998 -22.049  1.00 99.61  ? 57  LYS A NZ  1 
ATOM   376   N N   . PRO A 1 53  ? -42.719 -10.160 -26.270  1.00 68.30  ? 58  PRO A N   1 
ATOM   377   C CA  . PRO A 1 53  ? -42.474 -8.796  -25.796  1.00 60.26  ? 58  PRO A CA  1 
ATOM   378   C C   . PRO A 1 53  ? -43.269 -8.497  -24.533  1.00 64.63  ? 58  PRO A C   1 
ATOM   379   O O   . PRO A 1 53  ? -44.306 -9.102  -24.253  1.00 69.82  ? 58  PRO A O   1 
ATOM   380   C CB  . PRO A 1 53  ? -42.942 -7.923  -26.965  1.00 54.78  ? 58  PRO A CB  1 
ATOM   381   C CG  . PRO A 1 53  ? -43.977 -8.751  -27.645  1.00 53.36  ? 58  PRO A CG  1 
ATOM   382   C CD  . PRO A 1 53  ? -43.516 -10.179 -27.510  1.00 53.30  ? 58  PRO A CD  1 
ATOM   383   N N   . LEU A 1 54  ? -42.756 -7.546  -23.759  1.00 54.96  ? 59  LEU A N   1 
ATOM   384   C CA  . LEU A 1 54  ? -43.495 -6.985  -22.632  1.00 49.59  ? 59  LEU A CA  1 
ATOM   385   C C   . LEU A 1 54  ? -44.371 -5.858  -23.161  1.00 54.99  ? 59  LEU A C   1 
ATOM   386   O O   . LEU A 1 54  ? -43.875 -4.772  -23.480  1.00 64.88  ? 59  LEU A O   1 
ATOM   387   C CB  . LEU A 1 54  ? -42.551 -6.479  -21.546  1.00 49.01  ? 59  LEU A CB  1 
ATOM   388   C CG  . LEU A 1 54  ? -43.236 -5.796  -20.358  1.00 59.74  ? 59  LEU A CG  1 
ATOM   389   C CD1 . LEU A 1 54  ? -44.166 -6.763  -19.638  1.00 51.28  ? 59  LEU A CD1 1 
ATOM   390   C CD2 . LEU A 1 54  ? -42.207 -5.223  -19.402  1.00 51.98  ? 59  LEU A CD2 1 
ATOM   391   N N   . ILE A 1 55  ? -45.670 -6.117  -23.271  1.00 65.26  ? 60  ILE A N   1 
ATOM   392   C CA  . ILE A 1 55  ? -46.614 -5.164  -23.841  1.00 64.47  ? 60  ILE A CA  1 
ATOM   393   C C   . ILE A 1 55  ? -47.275 -4.427  -22.682  1.00 63.75  ? 60  ILE A C   1 
ATOM   394   O O   . ILE A 1 55  ? -48.164 -4.959  -22.011  1.00 66.11  ? 60  ILE A O   1 
ATOM   395   C CB  . ILE A 1 55  ? -47.643 -5.851  -24.742  1.00 63.42  ? 60  ILE A CB  1 
ATOM   396   C CG1 . ILE A 1 55  ? -46.949 -6.474  -25.956  1.00 58.46  ? 60  ILE A CG1 1 
ATOM   397   C CG2 . ILE A 1 55  ? -48.712 -4.861  -25.179  1.00 48.89  ? 60  ILE A CG2 1 
ATOM   398   C CD1 . ILE A 1 55  ? -47.908 -7.050  -26.976  1.00 66.99  ? 60  ILE A CD1 1 
ATOM   399   N N   . LEU A 1 56  ? -46.833 -3.197  -22.441  1.00 68.48  ? 61  LEU A N   1 
ATOM   400   C CA  . LEU A 1 56  ? -47.549 -2.294  -21.554  1.00 66.88  ? 61  LEU A CA  1 
ATOM   401   C C   . LEU A 1 56  ? -48.651 -1.616  -22.356  1.00 79.09  ? 61  LEU A C   1 
ATOM   402   O O   . LEU A 1 56  ? -48.385 -1.013  -23.401  1.00 91.13  ? 61  LEU A O   1 
ATOM   403   C CB  . LEU A 1 56  ? -46.593 -1.258  -20.960  1.00 67.78  ? 61  LEU A CB  1 
ATOM   404   C CG  . LEU A 1 56  ? -45.219 -1.766  -20.506  1.00 62.74  ? 61  LEU A CG  1 
ATOM   405   C CD1 . LEU A 1 56  ? -44.317 -0.602  -20.118  1.00 58.74  ? 61  LEU A CD1 1 
ATOM   406   C CD2 . LEU A 1 56  ? -45.341 -2.756  -19.352  1.00 52.99  ? 61  LEU A CD2 1 
ATOM   407   N N   . LYS A 1 57  ? -49.891 -1.723  -21.881  1.00 74.02  ? 62  LYS A N   1 
ATOM   408   C CA  . LYS A 1 57  ? -51.022 -1.312  -22.703  1.00 72.61  ? 62  LYS A CA  1 
ATOM   409   C C   . LYS A 1 57  ? -51.087 0.204   -22.835  1.00 70.05  ? 62  LYS A C   1 
ATOM   410   O O   . LYS A 1 57  ? -50.897 0.746   -23.928  1.00 96.81  ? 62  LYS A O   1 
ATOM   411   C CB  . LYS A 1 57  ? -52.330 -1.845  -22.113  1.00 80.30  ? 62  LYS A CB  1 
ATOM   412   C CG  . LYS A 1 57  ? -52.165 -3.050  -21.200  1.00 84.37  ? 62  LYS A CG  1 
ATOM   413   C CD  . LYS A 1 57  ? -53.513 -3.671  -20.867  1.00 85.81  ? 62  LYS A CD  1 
ATOM   414   C CE  . LYS A 1 57  ? -53.517 -4.290  -19.477  1.00 94.27  ? 62  LYS A CE  1 
ATOM   415   N NZ  . LYS A 1 57  ? -52.430 -5.291  -19.292  1.00 98.79  ? 62  LYS A NZ  1 
ATOM   416   N N   . ASP A 1 58  ? -51.328 0.896   -21.721  1.00 71.44  ? 63  ASP A N   1 
ATOM   417   C CA  . ASP A 1 58  ? -51.341 2.353   -21.693  1.00 72.81  ? 63  ASP A CA  1 
ATOM   418   C C   . ASP A 1 58  ? -50.493 2.878   -20.541  1.00 63.41  ? 63  ASP A C   1 
ATOM   419   O O   . ASP A 1 58  ? -50.639 4.038   -20.140  1.00 70.16  ? 63  ASP A O   1 
ATOM   420   C CB  . ASP A 1 58  ? -52.773 2.886   -21.591  1.00 84.92  ? 63  ASP A CB  1 
ATOM   421   C CG  . ASP A 1 58  ? -53.049 4.011   -22.572  1.00 90.29  ? 63  ASP A CG  1 
ATOM   422   O OD1 . ASP A 1 58  ? -52.145 4.843   -22.802  1.00 85.24  ? 63  ASP A OD1 1 
ATOM   423   O OD2 . ASP A 1 58  ? -54.171 4.061   -23.118  1.00 96.38  ? 63  ASP A OD2 1 
ATOM   424   N N   . CYS A 1 59  ? -49.615 2.037   -20.007  1.00 58.86  ? 64  CYS A N   1 
ATOM   425   C CA  . CYS A 1 59  ? -48.756 2.369   -18.884  1.00 70.18  ? 64  CYS A CA  1 
ATOM   426   C C   . CYS A 1 59  ? -47.341 2.606   -19.392  1.00 68.33  ? 64  CYS A C   1 
ATOM   427   O O   . CYS A 1 59  ? -46.870 1.905   -20.294  1.00 65.53  ? 64  CYS A O   1 
ATOM   428   C CB  . CYS A 1 59  ? -48.764 1.238   -17.846  1.00 67.69  ? 64  CYS A CB  1 
ATOM   429   S SG  . CYS A 1 59  ? -48.284 1.696   -16.159  1.00 125.28 ? 64  CYS A SG  1 
ATOM   430   N N   . SER A 1 60  ? -46.673 3.607   -18.830  1.00 58.21  ? 65  SER A N   1 
ATOM   431   C CA  . SER A 1 60  ? -45.260 3.786   -19.112  1.00 54.93  ? 65  SER A CA  1 
ATOM   432   C C   . SER A 1 60  ? -44.439 2.811   -18.273  1.00 59.56  ? 65  SER A C   1 
ATOM   433   O O   . SER A 1 60  ? -44.961 2.092   -17.416  1.00 62.03  ? 65  SER A O   1 
ATOM   434   C CB  . SER A 1 60  ? -44.830 5.223   -18.831  1.00 55.18  ? 65  SER A CB  1 
ATOM   435   O OG  . SER A 1 60  ? -44.766 5.460   -17.436  1.00 62.92  ? 65  SER A OG  1 
ATOM   436   N N   . VAL A 1 61  ? -43.131 2.789   -18.529  1.00 49.94  ? 66  VAL A N   1 
ATOM   437   C CA  . VAL A 1 61  ? -42.243 1.948   -17.731  1.00 52.73  ? 66  VAL A CA  1 
ATOM   438   C C   . VAL A 1 61  ? -42.242 2.405   -16.277  1.00 49.14  ? 66  VAL A C   1 
ATOM   439   O O   . VAL A 1 61  ? -42.264 1.583   -15.353  1.00 55.17  ? 66  VAL A O   1 
ATOM   440   C CB  . VAL A 1 61  ? -40.826 1.942   -18.332  1.00 46.38  ? 66  VAL A CB  1 
ATOM   441   C CG1 . VAL A 1 61  ? -39.822 1.371   -17.334  1.00 49.17  ? 66  VAL A CG1 1 
ATOM   442   C CG2 . VAL A 1 61  ? -40.808 1.137   -19.623  1.00 56.94  ? 66  VAL A CG2 1 
ATOM   443   N N   . ALA A 1 62  ? -42.228 3.723   -16.051  1.00 61.62  ? 67  ALA A N   1 
ATOM   444   C CA  . ALA A 1 62  ? -42.185 4.247   -14.688  1.00 48.38  ? 67  ALA A CA  1 
ATOM   445   C C   . ALA A 1 62  ? -43.426 3.854   -13.894  1.00 58.88  ? 67  ALA A C   1 
ATOM   446   O O   . ALA A 1 62  ? -43.320 3.433   -12.736  1.00 56.53  ? 67  ALA A O   1 
ATOM   447   C CB  . ALA A 1 62  ? -42.028 5.767   -14.717  1.00 42.44  ? 67  ALA A CB  1 
ATOM   448   N N   . GLY A 1 63  ? -44.610 3.983   -14.497  1.00 60.28  ? 68  GLY A N   1 
ATOM   449   C CA  . GLY A 1 63  ? -45.828 3.604   -13.796  1.00 56.90  ? 68  GLY A CA  1 
ATOM   450   C C   . GLY A 1 63  ? -45.907 2.114   -13.526  1.00 50.25  ? 68  GLY A C   1 
ATOM   451   O O   . GLY A 1 63  ? -46.431 1.687   -12.494  1.00 61.91  ? 68  GLY A O   1 
ATOM   452   N N   . TRP A 1 64  ? -45.396 1.305   -14.454  1.00 52.45  ? 69  TRP A N   1 
ATOM   453   C CA  . TRP A 1 64  ? -45.379 -0.141  -14.264  1.00 62.38  ? 69  TRP A CA  1 
ATOM   454   C C   . TRP A 1 64  ? -44.442 -0.545  -13.130  1.00 68.60  ? 69  TRP A C   1 
ATOM   455   O O   . TRP A 1 64  ? -44.787 -1.404  -12.310  1.00 66.20  ? 69  TRP A O   1 
ATOM   456   C CB  . TRP A 1 64  ? -44.986 -0.816  -15.578  1.00 46.47  ? 69  TRP A CB  1 
ATOM   457   C CG  . TRP A 1 64  ? -44.701 -2.277  -15.483  1.00 58.36  ? 69  TRP A CG  1 
ATOM   458   C CD1 . TRP A 1 64  ? -45.588 -3.269  -15.189  1.00 62.94  ? 69  TRP A CD1 1 
ATOM   459   C CD2 . TRP A 1 64  ? -43.442 -2.919  -15.719  1.00 53.63  ? 69  TRP A CD2 1 
ATOM   460   N NE1 . TRP A 1 64  ? -44.955 -4.490  -15.212  1.00 81.04  ? 69  TRP A NE1 1 
ATOM   461   C CE2 . TRP A 1 64  ? -43.637 -4.301  -15.537  1.00 50.82  ? 69  TRP A CE2 1 
ATOM   462   C CE3 . TRP A 1 64  ? -42.168 -2.458  -16.065  1.00 63.80  ? 69  TRP A CE3 1 
ATOM   463   C CZ2 . TRP A 1 64  ? -42.607 -5.226  -15.685  1.00 62.20  ? 69  TRP A CZ2 1 
ATOM   464   C CZ3 . TRP A 1 64  ? -41.147 -3.377  -16.211  1.00 61.87  ? 69  TRP A CZ3 1 
ATOM   465   C CH2 . TRP A 1 64  ? -41.371 -4.745  -16.020  1.00 62.14  ? 69  TRP A CH2 1 
ATOM   466   N N   . LEU A 1 65  ? -43.255 0.065   -13.061  1.00 63.08  ? 70  LEU A N   1 
ATOM   467   C CA  . LEU A 1 65  ? -42.291 -0.302  -12.026  1.00 61.15  ? 70  LEU A CA  1 
ATOM   468   C C   . LEU A 1 65  ? -42.767 0.122   -10.643  1.00 53.94  ? 70  LEU A C   1 
ATOM   469   O O   . LEU A 1 65  ? -42.741 -0.672  -9.697   1.00 47.32  ? 70  LEU A O   1 
ATOM   470   C CB  . LEU A 1 65  ? -40.928 0.321   -12.326  1.00 55.67  ? 70  LEU A CB  1 
ATOM   471   C CG  . LEU A 1 65  ? -39.991 -0.420  -13.276  1.00 63.68  ? 70  LEU A CG  1 
ATOM   472   C CD1 . LEU A 1 65  ? -38.682 0.337   -13.385  1.00 57.40  ? 70  LEU A CD1 1 
ATOM   473   C CD2 . LEU A 1 65  ? -39.750 -1.838  -12.793  1.00 55.37  ? 70  LEU A CD2 1 
ATOM   474   N N   . LEU A 1 66  ? -43.200 1.377   -10.505  1.00 49.62  ? 71  LEU A N   1 
ATOM   475   C CA  . LEU A 1 66  ? -43.587 1.895   -9.199   1.00 56.16  ? 71  LEU A CA  1 
ATOM   476   C C   . LEU A 1 66  ? -44.922 1.343   -8.715   1.00 58.46  ? 71  LEU A C   1 
ATOM   477   O O   . LEU A 1 66  ? -45.199 1.396   -7.512   1.00 57.11  ? 71  LEU A O   1 
ATOM   478   C CB  . LEU A 1 66  ? -43.636 3.421   -9.243   1.00 47.47  ? 71  LEU A CB  1 
ATOM   479   C CG  . LEU A 1 66  ? -42.261 4.086   -9.256   1.00 59.64  ? 71  LEU A CG  1 
ATOM   480   C CD1 . LEU A 1 66  ? -42.373 5.550   -9.625   1.00 49.33  ? 71  LEU A CD1 1 
ATOM   481   C CD2 . LEU A 1 66  ? -41.595 3.922   -7.898   1.00 48.58  ? 71  LEU A CD2 1 
ATOM   482   N N   . GLY A 1 67  ? -45.749 0.818   -9.614   1.00 55.08  ? 72  GLY A N   1 
ATOM   483   C CA  . GLY A 1 67  ? -47.040 0.287   -9.225   1.00 49.54  ? 72  GLY A CA  1 
ATOM   484   C C   . GLY A 1 67  ? -48.155 1.308   -9.300   1.00 62.29  ? 72  GLY A C   1 
ATOM   485   O O   . GLY A 1 67  ? -48.922 1.467   -8.345   1.00 60.50  ? 72  GLY A O   1 
ATOM   486   N N   . ASN A 1 68  ? -48.251 2.006   -10.428  1.00 59.28  ? 73  ASN A N   1 
ATOM   487   C CA  . ASN A 1 68  ? -49.334 2.957   -10.632  1.00 68.68  ? 73  ASN A CA  1 
ATOM   488   C C   . ASN A 1 68  ? -50.669 2.232   -10.485  1.00 66.53  ? 73  ASN A C   1 
ATOM   489   O O   . ASN A 1 68  ? -50.859 1.170   -11.095  1.00 63.58  ? 73  ASN A O   1 
ATOM   490   C CB  . ASN A 1 68  ? -49.213 3.600   -12.016  1.00 62.50  ? 73  ASN A CB  1 
ATOM   491   C CG  . ASN A 1 68  ? -50.199 4.739   -12.236  1.00 70.02  ? 73  ASN A CG  1 
ATOM   492   O OD1 . ASN A 1 68  ? -51.404 4.591   -12.032  1.00 63.26  ? 73  ASN A OD1 1 
ATOM   493   N ND2 . ASN A 1 68  ? -49.685 5.884   -12.671  1.00 76.50  ? 73  ASN A ND2 1 
ATOM   494   N N   . PRO A 1 69  ? -51.605 2.758   -9.689   1.00 67.40  ? 74  PRO A N   1 
ATOM   495   C CA  . PRO A 1 69  ? -52.837 2.001   -9.400   1.00 70.56  ? 74  PRO A CA  1 
ATOM   496   C C   . PRO A 1 69  ? -53.631 1.609   -10.635  1.00 69.71  ? 74  PRO A C   1 
ATOM   497   O O   . PRO A 1 69  ? -54.285 0.558   -10.627  1.00 78.63  ? 74  PRO A O   1 
ATOM   498   C CB  . PRO A 1 69  ? -53.629 2.959   -8.499   1.00 67.58  ? 74  PRO A CB  1 
ATOM   499   C CG  . PRO A 1 69  ? -52.588 3.812   -7.856   1.00 64.35  ? 74  PRO A CG  1 
ATOM   500   C CD  . PRO A 1 69  ? -51.517 3.998   -8.897   1.00 60.20  ? 74  PRO A CD  1 
ATOM   501   N N   . MET A 1 70  ? -53.594 2.410   -11.699  1.00 73.19  ? 75  MET A N   1 
ATOM   502   C CA  . MET A 1 70  ? -54.299 2.073   -12.931  1.00 75.77  ? 75  MET A CA  1 
ATOM   503   C C   . MET A 1 70  ? -53.504 1.145   -13.842  1.00 76.63  ? 75  MET A C   1 
ATOM   504   O O   . MET A 1 70  ? -53.901 0.956   -14.997  1.00 82.73  ? 75  MET A O   1 
ATOM   505   C CB  . MET A 1 70  ? -54.672 3.342   -13.702  1.00 76.95  ? 75  MET A CB  1 
ATOM   506   C CG  . MET A 1 70  ? -56.126 3.758   -13.559  1.00 82.55  ? 75  MET A CG  1 
ATOM   507   S SD  . MET A 1 70  ? -56.474 4.456   -11.938  1.00 115.55 ? 75  MET A SD  1 
ATOM   508   C CE  . MET A 1 70  ? -55.114 5.613   -11.792  1.00 79.76  ? 75  MET A CE  1 
ATOM   509   N N   . CYS A 1 71  ? -52.399 0.576   -13.370  1.00 68.22  ? 76  CYS A N   1 
ATOM   510   C CA  . CYS A 1 71  ? -51.622 -0.376  -14.148  1.00 66.89  ? 76  CYS A CA  1 
ATOM   511   C C   . CYS A 1 71  ? -51.659 -1.740  -13.469  1.00 77.46  ? 76  CYS A C   1 
ATOM   512   O O   . CYS A 1 71  ? -51.912 -1.853  -12.266  1.00 83.01  ? 76  CYS A O   1 
ATOM   513   C CB  . CYS A 1 71  ? -50.173 0.101   -14.336  1.00 76.60  ? 76  CYS A CB  1 
ATOM   514   S SG  . CYS A 1 71  ? -50.036 1.737   -15.127  1.00 94.93  ? 76  CYS A SG  1 
ATOM   515   N N   . ASP A 1 72  ? -51.417 -2.780  -14.266  1.00 75.31  ? 77  ASP A N   1 
ATOM   516   C CA  . ASP A 1 72  ? -51.554 -4.150  -13.787  1.00 84.02  ? 77  ASP A CA  1 
ATOM   517   C C   . ASP A 1 72  ? -50.590 -4.430  -12.639  1.00 89.68  ? 77  ASP A C   1 
ATOM   518   O O   . ASP A 1 72  ? -49.431 -4.005  -12.657  1.00 88.26  ? 77  ASP A O   1 
ATOM   519   C CB  . ASP A 1 72  ? -51.318 -5.129  -14.936  1.00 86.41  ? 77  ASP A CB  1 
ATOM   520   C CG  . ASP A 1 72  ? -51.433 -6.574  -14.503  1.00 100.61 ? 77  ASP A CG  1 
ATOM   521   O OD1 . ASP A 1 72  ? -52.534 -6.994  -14.086  1.00 94.80  ? 77  ASP A OD1 1 
ATOM   522   O OD2 . ASP A 1 72  ? -50.420 -7.294  -14.588  1.00 104.53 ? 77  ASP A OD2 1 
ATOM   523   N N   . GLU A 1 73  ? -51.079 -5.161  -11.636  1.00 95.71  ? 78  GLU A N   1 
ATOM   524   C CA  . GLU A 1 73  ? -50.372 -5.340  -10.374  1.00 92.43  ? 78  GLU A CA  1 
ATOM   525   C C   . GLU A 1 73  ? -49.485 -6.581  -10.334  1.00 91.59  ? 78  GLU A C   1 
ATOM   526   O O   . GLU A 1 73  ? -48.639 -6.687  -9.438   1.00 97.90  ? 78  GLU A O   1 
ATOM   527   C CB  . GLU A 1 73  ? -51.383 -5.402  -9.221   1.00 88.92  ? 78  GLU A CB  1 
ATOM   528   C CG  . GLU A 1 73  ? -50.777 -5.235  -7.834   1.00 97.98  ? 78  GLU A CG  1 
ATOM   529   C CD  . GLU A 1 73  ? -51.640 -5.836  -6.742   1.00 100.66 ? 78  GLU A CD  1 
ATOM   530   O OE1 . GLU A 1 73  ? -52.873 -5.641  -6.776   1.00 106.00 ? 78  GLU A OE1 1 
ATOM   531   O OE2 . GLU A 1 73  ? -51.082 -6.516  -5.854   1.00 99.35  ? 78  GLU A OE2 1 
ATOM   532   N N   . PHE A 1 74  ? -49.637 -7.514  -11.269  1.00 88.49  ? 79  PHE A N   1 
ATOM   533   C CA  . PHE A 1 74  ? -48.940 -8.792  -11.206  1.00 97.23  ? 79  PHE A CA  1 
ATOM   534   C C   . PHE A 1 74  ? -48.080 -8.983  -12.443  1.00 97.32  ? 79  PHE A C   1 
ATOM   535   O O   . PHE A 1 74  ? -48.573 -8.873  -13.569  1.00 92.92  ? 79  PHE A O   1 
ATOM   536   C CB  . PHE A 1 74  ? -49.933 -9.950  -11.078  1.00 91.60  ? 79  PHE A CB  1 
ATOM   537   C CG  . PHE A 1 74  ? -50.685 -9.957  -9.783   1.00 88.05  ? 79  PHE A CG  1 
ATOM   538   C CD1 . PHE A 1 74  ? -51.957 -9.415  -9.701   1.00 94.27  ? 79  PHE A CD1 1 
ATOM   539   C CD2 . PHE A 1 74  ? -50.116 -10.498 -8.643   1.00 84.51  ? 79  PHE A CD2 1 
ATOM   540   C CE1 . PHE A 1 74  ? -52.650 -9.418  -8.505   1.00 98.22  ? 79  PHE A CE1 1 
ATOM   541   C CE2 . PHE A 1 74  ? -50.802 -10.504 -7.446   1.00 85.70  ? 79  PHE A CE2 1 
ATOM   542   C CZ  . PHE A 1 74  ? -52.070 -9.963  -7.376   1.00 93.51  ? 79  PHE A CZ  1 
ATOM   543   N N   . ILE A 1 75  ? -46.801 -9.290  -12.240  1.00 101.54 ? 80  ILE A N   1 
ATOM   544   C CA  . ILE A 1 75  ? -45.953 -9.600  -13.383  1.00 102.23 ? 80  ILE A CA  1 
ATOM   545   C C   . ILE A 1 75  ? -46.331 -10.989 -13.889  1.00 95.21  ? 80  ILE A C   1 
ATOM   546   O O   . ILE A 1 75  ? -46.303 -11.979 -13.147  1.00 92.62  ? 80  ILE A O   1 
ATOM   547   C CB  . ILE A 1 75  ? -44.458 -9.471  -13.035  1.00 83.97  ? 80  ILE A CB  1 
ATOM   548   C CG1 . ILE A 1 75  ? -43.871 -10.734 -12.401  1.00 103.91 ? 80  ILE A CG1 1 
ATOM   549   C CG2 . ILE A 1 75  ? -44.236 -8.293  -12.090  1.00 85.12  ? 80  ILE A CG2 1 
ATOM   550   C CD1 . ILE A 1 75  ? -42.369 -10.789 -12.464  1.00 88.12  ? 80  ILE A CD1 1 
ATOM   551   N N   . ARG A 1 76  ? -46.786 -11.053 -15.136  1.00 86.94  ? 81  ARG A N   1 
ATOM   552   C CA  . ARG A 1 76  ? -47.141 -12.318 -15.758  1.00 100.32 ? 81  ARG A CA  1 
ATOM   553   C C   . ARG A 1 76  ? -46.008 -12.878 -16.601  1.00 96.37  ? 81  ARG A C   1 
ATOM   554   O O   . ARG A 1 76  ? -46.040 -14.061 -16.960  1.00 96.85  ? 81  ARG A O   1 
ATOM   555   C CB  . ARG A 1 76  ? -48.401 -12.144 -16.618  1.00 111.13 ? 81  ARG A CB  1 
ATOM   556   C CG  . ARG A 1 76  ? -49.067 -13.444 -17.048  1.00 114.78 ? 81  ARG A CG  1 
ATOM   557   C CD  . ARG A 1 76  ? -50.337 -13.185 -17.844  1.00 119.16 ? 81  ARG A CD  1 
ATOM   558   N NE  . ARG A 1 76  ? -51.313 -12.416 -17.079  1.00 137.83 ? 81  ARG A NE  1 
ATOM   559   C CZ  . ARG A 1 76  ? -52.554 -12.171 -17.477  1.00 131.29 ? 81  ARG A CZ  1 
ATOM   560   N NH1 . ARG A 1 76  ? -53.015 -12.631 -18.629  1.00 124.79 ? 81  ARG A NH1 1 
ATOM   561   N NH2 . ARG A 1 76  ? -53.354 -11.449 -16.698  1.00 126.83 ? 81  ARG A NH2 1 
ATOM   562   N N   . VAL A 1 77  ? -45.005 -12.062 -16.903  1.00 91.00  ? 82  VAL A N   1 
ATOM   563   C CA  . VAL A 1 77  ? -43.932 -12.438 -17.815  1.00 89.06  ? 82  VAL A CA  1 
ATOM   564   C C   . VAL A 1 77  ? -42.594 -12.303 -17.095  1.00 81.96  ? 82  VAL A C   1 
ATOM   565   O O   . VAL A 1 77  ? -42.193 -11.186 -16.739  1.00 78.34  ? 82  VAL A O   1 
ATOM   566   C CB  . VAL A 1 77  ? -43.969 -11.577 -19.087  1.00 82.96  ? 82  VAL A CB  1 
ATOM   567   C CG1 . VAL A 1 77  ? -43.076 -12.170 -20.141  1.00 94.38  ? 82  VAL A CG1 1 
ATOM   568   C CG2 . VAL A 1 77  ? -45.394 -11.454 -19.609  1.00 85.03  ? 82  VAL A CG2 1 
ATOM   569   N N   . PRO A 1 78  ? -41.881 -13.405 -16.846  1.00 79.28  ? 83  PRO A N   1 
ATOM   570   C CA  . PRO A 1 78  ? -40.552 -13.300 -16.230  1.00 69.13  ? 83  PRO A CA  1 
ATOM   571   C C   . PRO A 1 78  ? -39.444 -12.926 -17.201  1.00 63.71  ? 83  PRO A C   1 
ATOM   572   O O   . PRO A 1 78  ? -38.322 -12.660 -16.751  1.00 70.51  ? 83  PRO A O   1 
ATOM   573   C CB  . PRO A 1 78  ? -40.325 -14.706 -15.662  1.00 77.08  ? 83  PRO A CB  1 
ATOM   574   C CG  . PRO A 1 78  ? -41.089 -15.593 -16.585  1.00 72.57  ? 83  PRO A CG  1 
ATOM   575   C CD  . PRO A 1 78  ? -42.305 -14.806 -17.014  1.00 74.54  ? 83  PRO A CD  1 
ATOM   576   N N   . GLU A 1 79  A -39.709 -12.900 -18.506  1.00 65.05  ? 83  GLU A N   1 
ATOM   577   C CA  . GLU A 1 79  A -38.669 -12.608 -19.483  1.00 66.61  ? 83  GLU A CA  1 
ATOM   578   C C   . GLU A 1 79  A -39.308 -12.045 -20.744  1.00 62.95  ? 83  GLU A C   1 
ATOM   579   O O   . GLU A 1 79  A -40.300 -12.585 -21.236  1.00 79.93  ? 83  GLU A O   1 
ATOM   580   C CB  . GLU A 1 79  A -37.857 -13.864 -19.821  1.00 57.58  ? 83  GLU A CB  1 
ATOM   581   C CG  . GLU A 1 79  A -38.713 -15.058 -20.216  1.00 79.54  ? 83  GLU A CG  1 
ATOM   582   C CD  . GLU A 1 79  A -37.992 -16.018 -21.141  1.00 93.51  ? 83  GLU A CD  1 
ATOM   583   O OE1 . GLU A 1 79  A -36.780 -15.826 -21.374  1.00 86.42  ? 83  GLU A OE1 1 
ATOM   584   O OE2 . GLU A 1 79  A -38.642 -16.963 -21.639  1.00 88.78  ? 83  GLU A OE2 1 
ATOM   585   N N   . TRP A 1 80  ? -38.723 -10.974 -21.275  1.00 63.97  ? 84  TRP A N   1 
ATOM   586   C CA  . TRP A 1 80  ? -39.216 -10.379 -22.507  1.00 56.89  ? 84  TRP A CA  1 
ATOM   587   C C   . TRP A 1 80  ? -38.042 -9.985  -23.393  1.00 57.46  ? 84  TRP A C   1 
ATOM   588   O O   . TRP A 1 80  ? -36.925 -9.761  -22.920  1.00 67.34  ? 84  TRP A O   1 
ATOM   589   C CB  . TRP A 1 80  ? -40.116 -9.166  -22.234  1.00 49.28  ? 84  TRP A CB  1 
ATOM   590   C CG  . TRP A 1 80  ? -39.484 -8.126  -21.374  1.00 58.77  ? 84  TRP A CG  1 
ATOM   591   C CD1 . TRP A 1 80  ? -38.709 -7.083  -21.786  1.00 59.93  ? 84  TRP A CD1 1 
ATOM   592   C CD2 . TRP A 1 80  ? -39.578 -8.019  -19.950  1.00 59.64  ? 84  TRP A CD2 1 
ATOM   593   N NE1 . TRP A 1 80  ? -38.310 -6.334  -20.707  1.00 55.80  ? 84  TRP A NE1 1 
ATOM   594   C CE2 . TRP A 1 80  ? -38.831 -6.888  -19.567  1.00 60.61  ? 84  TRP A CE2 1 
ATOM   595   C CE3 . TRP A 1 80  ? -40.219 -8.771  -18.962  1.00 52.20  ? 84  TRP A CE3 1 
ATOM   596   C CZ2 . TRP A 1 80  ? -38.709 -6.489  -18.237  1.00 58.36  ? 84  TRP A CZ2 1 
ATOM   597   C CZ3 . TRP A 1 80  ? -40.096 -8.375  -17.641  1.00 61.91  ? 84  TRP A CZ3 1 
ATOM   598   C CH2 . TRP A 1 80  ? -39.345 -7.245  -17.291  1.00 63.49  ? 84  TRP A CH2 1 
ATOM   599   N N   . SER A 1 81  ? -38.315 -9.913  -24.697  1.00 57.91  ? 85  SER A N   1 
ATOM   600   C CA  . SER A 1 81  ? -37.302 -9.578  -25.690  1.00 60.72  ? 85  SER A CA  1 
ATOM   601   C C   . SER A 1 81  ? -37.270 -8.094  -26.023  1.00 53.08  ? 85  SER A C   1 
ATOM   602   O O   . SER A 1 81  ? -36.206 -7.568  -26.365  1.00 52.39  ? 85  SER A O   1 
ATOM   603   C CB  . SER A 1 81  ? -37.538 -10.378 -26.973  1.00 61.57  ? 85  SER A CB  1 
ATOM   604   O OG  . SER A 1 81  ? -38.815 -10.093 -27.520  1.00 62.33  ? 85  SER A OG  1 
ATOM   605   N N   . TYR A 1 82  ? -38.411 -7.417  -25.946  1.00 49.82  ? 86  TYR A N   1 
ATOM   606   C CA  . TYR A 1 82  ? -38.468 -5.972  -26.111  1.00 46.50  ? 86  TYR A CA  1 
ATOM   607   C C   . TYR A 1 82  ? -39.735 -5.468  -25.441  1.00 47.59  ? 86  TYR A C   1 
ATOM   608   O O   . TYR A 1 82  ? -40.634 -6.245  -25.112  1.00 55.49  ? 86  TYR A O   1 
ATOM   609   C CB  . TYR A 1 82  ? -38.417 -5.557  -27.587  1.00 49.66  ? 86  TYR A CB  1 
ATOM   610   C CG  . TYR A 1 82  ? -39.549 -6.079  -28.443  1.00 51.25  ? 86  TYR A CG  1 
ATOM   611   C CD1 . TYR A 1 82  ? -39.530 -7.376  -28.940  1.00 53.59  ? 86  TYR A CD1 1 
ATOM   612   C CD2 . TYR A 1 82  ? -40.626 -5.266  -28.776  1.00 45.52  ? 86  TYR A CD2 1 
ATOM   613   C CE1 . TYR A 1 82  ? -40.558 -7.854  -29.730  1.00 57.56  ? 86  TYR A CE1 1 
ATOM   614   C CE2 . TYR A 1 82  ? -41.658 -5.736  -29.569  1.00 57.20  ? 86  TYR A CE2 1 
ATOM   615   C CZ  . TYR A 1 82  ? -41.617 -7.030  -30.043  1.00 54.72  ? 86  TYR A CZ  1 
ATOM   616   O OH  . TYR A 1 82  ? -42.641 -7.502  -30.830  1.00 53.80  ? 86  TYR A OH  1 
ATOM   617   N N   . ILE A 1 83  ? -39.787 -4.158  -25.227  1.00 48.70  ? 87  ILE A N   1 
ATOM   618   C CA  . ILE A 1 83  ? -40.904 -3.510  -24.551  1.00 46.10  ? 87  ILE A CA  1 
ATOM   619   C C   . ILE A 1 83  ? -41.699 -2.717  -25.577  1.00 56.22  ? 87  ILE A C   1 
ATOM   620   O O   . ILE A 1 83  ? -41.123 -2.019  -26.420  1.00 58.67  ? 87  ILE A O   1 
ATOM   621   C CB  . ILE A 1 83  ? -40.419 -2.597  -23.407  1.00 48.58  ? 87  ILE A CB  1 
ATOM   622   C CG1 . ILE A 1 83  ? -39.832 -3.429  -22.267  1.00 47.64  ? 87  ILE A CG1 1 
ATOM   623   C CG2 . ILE A 1 83  ? -41.548 -1.712  -22.898  1.00 39.71  ? 87  ILE A CG2 1 
ATOM   624   C CD1 . ILE A 1 83  ? -39.325 -2.594  -21.112  1.00 44.12  ? 87  ILE A CD1 1 
ATOM   625   N N   . VAL A 1 84  ? -43.024 -2.832  -25.512  1.00 62.10  ? 88  VAL A N   1 
ATOM   626   C CA  . VAL A 1 84  ? -43.923 -2.056  -26.356  1.00 51.50  ? 88  VAL A CA  1 
ATOM   627   C C   . VAL A 1 84  ? -44.629 -1.032  -25.478  1.00 53.27  ? 88  VAL A C   1 
ATOM   628   O O   . VAL A 1 84  ? -45.290 -1.390  -24.495  1.00 55.33  ? 88  VAL A O   1 
ATOM   629   C CB  . VAL A 1 84  ? -44.938 -2.946  -27.086  1.00 49.82  ? 88  VAL A CB  1 
ATOM   630   C CG1 . VAL A 1 84  ? -45.788 -2.106  -28.029  1.00 41.54  ? 88  VAL A CG1 1 
ATOM   631   C CG2 . VAL A 1 84  ? -44.226 -4.051  -27.844  1.00 56.16  ? 88  VAL A CG2 1 
ATOM   632   N N   . GLU A 1 85  ? -44.480 0.240   -25.831  1.00 53.98  ? 89  GLU A N   1 
ATOM   633   C CA  . GLU A 1 85  ? -45.194 1.340   -25.205  1.00 48.02  ? 89  GLU A CA  1 
ATOM   634   C C   . GLU A 1 85  ? -46.009 2.065   -26.262  1.00 62.35  ? 89  GLU A C   1 
ATOM   635   O O   . GLU A 1 85  ? -45.656 2.067   -27.445  1.00 62.03  ? 89  GLU A O   1 
ATOM   636   C CB  . GLU A 1 85  ? -44.236 2.341   -24.540  1.00 54.02  ? 89  GLU A CB  1 
ATOM   637   C CG  . GLU A 1 85  ? -43.944 2.096   -23.070  1.00 66.47  ? 89  GLU A CG  1 
ATOM   638   C CD  . GLU A 1 85  ? -43.066 3.185   -22.474  1.00 71.02  ? 89  GLU A CD  1 
ATOM   639   O OE1 . GLU A 1 85  ? -42.544 4.020   -23.244  1.00 65.64  ? 89  GLU A OE1 1 
ATOM   640   O OE2 . GLU A 1 85  ? -42.897 3.211   -21.237  1.00 73.93  ? 89  GLU A OE2 1 
ATOM   641   N N   . ARG A 1 86  ? -47.105 2.679   -25.836  1.00 63.25  ? 90  ARG A N   1 
ATOM   642   C CA  . ARG A 1 86  ? -47.788 3.591   -26.733  1.00 59.98  ? 90  ARG A CA  1 
ATOM   643   C C   . ARG A 1 86  ? -47.026 4.911   -26.797  1.00 69.69  ? 90  ARG A C   1 
ATOM   644   O O   . ARG A 1 86  ? -46.164 5.199   -25.962  1.00 62.81  ? 90  ARG A O   1 
ATOM   645   C CB  . ARG A 1 86  ? -49.236 3.807   -26.293  1.00 58.12  ? 90  ARG A CB  1 
ATOM   646   C CG  . ARG A 1 86  ? -50.121 2.602   -26.573  1.00 67.82  ? 90  ARG A CG  1 
ATOM   647   C CD  . ARG A 1 86  ? -51.587 2.878   -26.284  1.00 74.03  ? 90  ARG A CD  1 
ATOM   648   N NE  . ARG A 1 86  ? -52.424 2.622   -27.450  1.00 77.78  ? 90  ARG A NE  1 
ATOM   649   C CZ  . ARG A 1 86  ? -52.748 1.414   -27.893  1.00 91.84  ? 90  ARG A CZ  1 
ATOM   650   N NH1 . ARG A 1 86  ? -52.308 0.316   -27.298  1.00 89.56  ? 90  ARG A NH1 1 
ATOM   651   N NH2 . ARG A 1 86  ? -53.529 1.304   -28.964  1.00 88.78  ? 90  ARG A NH2 1 
ATOM   652   N N   . ALA A 1 87  ? -47.343 5.710   -27.820  1.00 64.78  ? 91  ALA A N   1 
ATOM   653   C CA  . ALA A 1 87  ? -46.584 6.932   -28.067  1.00 67.98  ? 91  ALA A CA  1 
ATOM   654   C C   . ALA A 1 87  ? -46.606 7.851   -26.852  1.00 69.02  ? 91  ALA A C   1 
ATOM   655   O O   . ALA A 1 87  ? -45.567 8.377   -26.437  1.00 66.81  ? 91  ALA A O   1 
ATOM   656   C CB  . ALA A 1 87  ? -47.135 7.648   -29.301  1.00 68.67  ? 91  ALA A CB  1 
ATOM   657   N N   . ASN A 1 88  ? -47.784 8.050   -26.261  1.00 65.80  ? 92  ASN A N   1 
ATOM   658   C CA  . ASN A 1 88  ? -47.942 8.866   -25.059  1.00 69.78  ? 92  ASN A CA  1 
ATOM   659   C C   . ASN A 1 88  ? -48.766 8.078   -24.051  1.00 65.10  ? 92  ASN A C   1 
ATOM   660   O O   . ASN A 1 88  ? -49.999 8.200   -24.012  1.00 70.59  ? 92  ASN A O   1 
ATOM   661   C CB  . ASN A 1 88  ? -48.593 10.208  -25.383  1.00 63.89  ? 92  ASN A CB  1 
ATOM   662   C CG  . ASN A 1 88  ? -47.937 10.902  -26.560  1.00 72.08  ? 92  ASN A CG  1 
ATOM   663   O OD1 . ASN A 1 88  ? -48.330 10.702  -27.709  1.00 64.80  ? 92  ASN A OD1 1 
ATOM   664   N ND2 . ASN A 1 88  ? -46.929 11.721  -26.279  1.00 68.21  ? 92  ASN A ND2 1 
ATOM   665   N N   . PRO A 1 89  ? -48.123 7.248   -23.229  1.00 74.35  ? 93  PRO A N   1 
ATOM   666   C CA  . PRO A 1 89  ? -48.871 6.458   -22.242  1.00 62.83  ? 93  PRO A CA  1 
ATOM   667   C C   . PRO A 1 89  ? -49.650 7.346   -21.283  1.00 61.70  ? 93  PRO A C   1 
ATOM   668   O O   . PRO A 1 89  ? -49.182 8.408   -20.868  1.00 59.32  ? 93  PRO A O   1 
ATOM   669   C CB  . PRO A 1 89  ? -47.775 5.671   -21.514  1.00 53.16  ? 93  PRO A CB  1 
ATOM   670   C CG  . PRO A 1 89  ? -46.631 5.630   -22.477  1.00 60.32  ? 93  PRO A CG  1 
ATOM   671   C CD  . PRO A 1 89  ? -46.683 6.939   -23.211  1.00 67.25  ? 93  PRO A CD  1 
ATOM   672   N N   . ALA A 1 90  ? -50.857 6.896   -20.936  1.00 60.84  ? 94  ALA A N   1 
ATOM   673   C CA  . ALA A 1 90  ? -51.731 7.678   -20.070  1.00 71.99  ? 94  ALA A CA  1 
ATOM   674   C C   . ALA A 1 90  ? -51.322 7.610   -18.602  1.00 68.47  ? 94  ALA A C   1 
ATOM   675   O O   . ALA A 1 90  ? -51.507 8.588   -17.870  1.00 66.42  ? 94  ALA A O   1 
ATOM   676   C CB  . ALA A 1 90  ? -53.179 7.210   -20.228  1.00 55.80  ? 94  ALA A CB  1 
ATOM   677   N N   . ASN A 1 91  ? -50.772 6.485   -18.154  1.00 59.33  ? 95  ASN A N   1 
ATOM   678   C CA  . ASN A 1 91  ? -50.486 6.251   -16.739  1.00 56.93  ? 95  ASN A CA  1 
ATOM   679   C C   . ASN A 1 91  ? -48.972 6.179   -16.551  1.00 63.30  ? 95  ASN A C   1 
ATOM   680   O O   . ASN A 1 91  ? -48.379 5.100   -16.592  1.00 66.73  ? 95  ASN A O   1 
ATOM   681   C CB  . ASN A 1 91  ? -51.167 4.966   -16.264  1.00 62.90  ? 95  ASN A CB  1 
ATOM   682   C CG  . ASN A 1 91  ? -52.633 4.901   -16.657  1.00 70.05  ? 95  ASN A CG  1 
ATOM   683   O OD1 . ASN A 1 91  ? -53.411 5.806   -16.354  1.00 64.79  ? 95  ASN A OD1 1 
ATOM   684   N ND2 . ASN A 1 91  ? -53.014 3.829   -17.344  1.00 68.44  ? 95  ASN A ND2 1 
ATOM   685   N N   . ASP A 1 92  ? -48.340 7.336   -16.352  1.00 66.30  ? 96  ASP A N   1 
ATOM   686   C CA  . ASP A 1 92  ? -46.895 7.371   -16.143  1.00 71.80  ? 96  ASP A CA  1 
ATOM   687   C C   . ASP A 1 92  ? -46.514 7.566   -14.679  1.00 71.05  ? 96  ASP A C   1 
ATOM   688   O O   . ASP A 1 92  ? -45.892 6.692   -14.070  1.00 82.36  ? 96  ASP A O   1 
ATOM   689   C CB  . ASP A 1 92  ? -46.276 8.481   -16.999  1.00 74.93  ? 96  ASP A CB  1 
ATOM   690   C CG  . ASP A 1 92  ? -44.839 8.772   -16.619  1.00 68.19  ? 96  ASP A CG  1 
ATOM   691   O OD1 . ASP A 1 92  ? -44.001 7.848   -16.704  1.00 72.86  ? 96  ASP A OD1 1 
ATOM   692   O OD2 . ASP A 1 92  ? -44.547 9.924   -16.237  1.00 74.54  ? 96  ASP A OD2 1 
ATOM   693   N N   . LEU A 1 93  A -46.906 8.693   -14.092  1.00 65.26  ? 96  LEU A N   1 
ATOM   694   C CA  . LEU A 1 93  A -46.586 9.027   -12.701  1.00 66.71  ? 96  LEU A CA  1 
ATOM   695   C C   . LEU A 1 93  A -47.803 9.780   -12.175  1.00 65.56  ? 96  LEU A C   1 
ATOM   696   O O   . LEU A 1 93  A -47.905 10.998  -12.343  1.00 68.01  ? 96  LEU A O   1 
ATOM   697   C CB  . LEU A 1 93  A -45.313 9.858   -12.585  1.00 59.61  ? 96  LEU A CB  1 
ATOM   698   C CG  . LEU A 1 93  A -43.963 9.166   -12.781  1.00 72.52  ? 96  LEU A CG  1 
ATOM   699   C CD1 . LEU A 1 93  A -42.837 10.189  -12.771  1.00 54.54  ? 96  LEU A CD1 1 
ATOM   700   C CD2 . LEU A 1 93  A -43.739 8.122   -11.704  1.00 51.69  ? 96  LEU A CD2 1 
ATOM   701   N N   . CYS A 1 94  ? -48.723 9.043   -11.550  1.00 61.23  ? 97  CYS A N   1 
ATOM   702   C CA  . CYS A 1 94  ? -49.972 9.648   -11.104  1.00 70.69  ? 97  CYS A CA  1 
ATOM   703   C C   . CYS A 1 94  ? -49.706 10.820  -10.167  1.00 57.61  ? 97  CYS A C   1 
ATOM   704   O O   . CYS A 1 94  ? -50.255 11.913  -10.351  1.00 56.68  ? 97  CYS A O   1 
ATOM   705   C CB  . CYS A 1 94  ? -50.856 8.589   -10.443  1.00 59.26  ? 97  CYS A CB  1 
ATOM   706   S SG  . CYS A 1 94  ? -50.064 7.637   -9.131   1.00 80.90  ? 97  CYS A SG  1 
ATOM   707   N N   . TYR A 1 95  ? -48.845 10.624  -9.176   1.00 45.43  ? 98  TYR A N   1 
ATOM   708   C CA  . TYR A 1 95  ? -48.369 11.751  -8.385   1.00 64.51  ? 98  TYR A CA  1 
ATOM   709   C C   . TYR A 1 95  ? -47.233 12.437  -9.134   1.00 63.27  ? 98  TYR A C   1 
ATOM   710   O O   . TYR A 1 95  ? -46.241 11.779  -9.466   1.00 57.24  ? 98  TYR A O   1 
ATOM   711   C CB  . TYR A 1 95  ? -47.901 11.303  -7.008   1.00 53.55  ? 98  TYR A CB  1 
ATOM   712   C CG  . TYR A 1 95  ? -47.835 12.441  -6.015   1.00 57.87  ? 98  TYR A CG  1 
ATOM   713   C CD1 . TYR A 1 95  ? -46.716 13.261  -5.943   1.00 51.57  ? 98  TYR A CD1 1 
ATOM   714   C CD2 . TYR A 1 95  ? -48.899 12.706  -5.161   1.00 52.18  ? 98  TYR A CD2 1 
ATOM   715   C CE1 . TYR A 1 95  ? -46.654 14.308  -5.043   1.00 57.37  ? 98  TYR A CE1 1 
ATOM   716   C CE2 . TYR A 1 95  ? -48.846 13.752  -4.256   1.00 54.96  ? 98  TYR A CE2 1 
ATOM   717   C CZ  . TYR A 1 95  ? -47.721 14.548  -4.202   1.00 58.97  ? 98  TYR A CZ  1 
ATOM   718   O OH  . TYR A 1 95  ? -47.661 15.591  -3.308   1.00 55.40  ? 98  TYR A OH  1 
ATOM   719   N N   . PRO A 1 96  ? -47.332 13.736  -9.415   1.00 56.26  ? 99  PRO A N   1 
ATOM   720   C CA  . PRO A 1 96  ? -46.340 14.383  -10.283  1.00 56.70  ? 99  PRO A CA  1 
ATOM   721   C C   . PRO A 1 96  ? -44.944 14.364  -9.679   1.00 51.55  ? 99  PRO A C   1 
ATOM   722   O O   . PRO A 1 96  ? -44.765 14.382  -8.459   1.00 49.90  ? 99  PRO A O   1 
ATOM   723   C CB  . PRO A 1 96  ? -46.870 15.815  -10.421  1.00 45.02  ? 99  PRO A CB  1 
ATOM   724   C CG  . PRO A 1 96  ? -47.703 16.025  -9.199   1.00 58.76  ? 99  PRO A CG  1 
ATOM   725   C CD  . PRO A 1 96  ? -48.329 14.691  -8.903   1.00 59.81  ? 99  PRO A CD  1 
ATOM   726   N N   . GLY A 1 97  ? -43.948 14.326  -10.560  1.00 46.92  ? 100 GLY A N   1 
ATOM   727   C CA  . GLY A 1 97  ? -42.563 14.295  -10.141  1.00 50.67  ? 100 GLY A CA  1 
ATOM   728   C C   . GLY A 1 97  ? -41.639 13.821  -11.241  1.00 59.49  ? 100 GLY A C   1 
ATOM   729   O O   . GLY A 1 97  ? -41.787 14.225  -12.399  1.00 56.85  ? 100 GLY A O   1 
ATOM   730   N N   . SER A 1 98  ? -40.683 12.960  -10.898  1.00 49.10  ? 101 SER A N   1 
ATOM   731   C CA  . SER A 1 98  ? -39.720 12.481  -11.878  1.00 56.43  ? 101 SER A CA  1 
ATOM   732   C C   . SER A 1 98  ? -39.123 11.170  -11.394  1.00 53.66  ? 101 SER A C   1 
ATOM   733   O O   . SER A 1 98  ? -39.158 10.849  -10.203  1.00 49.66  ? 101 SER A O   1 
ATOM   734   C CB  . SER A 1 98  ? -38.610 13.508  -12.124  1.00 51.91  ? 101 SER A CB  1 
ATOM   735   O OG  . SER A 1 98  ? -37.804 13.668  -10.969  1.00 59.66  ? 101 SER A OG  1 
ATOM   736   N N   . LEU A 1 99  ? -38.575 10.416  -12.344  1.00 53.70  ? 102 LEU A N   1 
ATOM   737   C CA  . LEU A 1 99  ? -37.805 9.212   -12.063  1.00 47.04  ? 102 LEU A CA  1 
ATOM   738   C C   . LEU A 1 99  ? -36.398 9.427   -12.601  1.00 48.73  ? 102 LEU A C   1 
ATOM   739   O O   . LEU A 1 99  ? -36.221 9.702   -13.793  1.00 49.59  ? 102 LEU A O   1 
ATOM   740   C CB  . LEU A 1 99  ? -38.460 7.979   -12.691  1.00 42.29  ? 102 LEU A CB  1 
ATOM   741   C CG  . LEU A 1 99  ? -37.727 6.641   -12.549  1.00 55.32  ? 102 LEU A CG  1 
ATOM   742   C CD1 . LEU A 1 99  ? -37.344 6.368   -11.102  1.00 46.63  ? 102 LEU A CD1 1 
ATOM   743   C CD2 . LEU A 1 99  ? -38.590 5.512   -13.091  1.00 54.92  ? 102 LEU A CD2 1 
ATOM   744   N N   . ASN A 1 100 ? -35.405 9.305   -11.724  1.00 45.58  ? 103 ASN A N   1 
ATOM   745   C CA  . ASN A 1 100 ? -34.037 9.661   -12.076  1.00 44.85  ? 103 ASN A CA  1 
ATOM   746   C C   . ASN A 1 100 ? -33.437 8.648   -13.047  1.00 49.20  ? 103 ASN A C   1 
ATOM   747   O O   . ASN A 1 100 ? -33.655 7.440   -12.923  1.00 43.24  ? 103 ASN A O   1 
ATOM   748   C CB  . ASN A 1 100 ? -33.188 9.752   -10.808  1.00 51.37  ? 103 ASN A CB  1 
ATOM   749   C CG  . ASN A 1 100 ? -31.807 10.319  -11.066  1.00 65.04  ? 103 ASN A CG  1 
ATOM   750   O OD1 . ASN A 1 100 ? -30.803 9.612   -10.965  1.00 52.79  ? 103 ASN A OD1 1 
ATOM   751   N ND2 . ASN A 1 100 ? -31.749 11.603  -11.400  1.00 53.94  ? 103 ASN A ND2 1 
ATOM   752   N N   . ASP A 1 101 ? -32.668 9.155   -14.015  1.00 46.60  ? 104 ASP A N   1 
ATOM   753   C CA  . ASP A 1 101 ? -32.001 8.325   -15.024  1.00 49.85  ? 104 ASP A CA  1 
ATOM   754   C C   . ASP A 1 101 ? -33.001 7.416   -15.735  1.00 46.48  ? 104 ASP A C   1 
ATOM   755   O O   . ASP A 1 101 ? -32.764 6.223   -15.941  1.00 49.33  ? 104 ASP A O   1 
ATOM   756   C CB  . ASP A 1 101 ? -30.865 7.511   -14.400  1.00 55.68  ? 104 ASP A CB  1 
ATOM   757   C CG  . ASP A 1 101 ? -29.600 8.325   -14.201  1.00 72.34  ? 104 ASP A CG  1 
ATOM   758   O OD1 . ASP A 1 101 ? -29.223 9.076   -15.126  1.00 81.42  ? 104 ASP A OD1 1 
ATOM   759   O OD2 . ASP A 1 101 ? -28.982 8.216   -13.121  1.00 79.74  ? 104 ASP A OD2 1 
ATOM   760   N N   . TYR A 1 102 ? -34.137 8.003   -16.114  1.00 43.14  ? 105 TYR A N   1 
ATOM   761   C CA  . TYR A 1 102 ? -35.258 7.217   -16.619  1.00 46.07  ? 105 TYR A CA  1 
ATOM   762   C C   . TYR A 1 102 ? -34.916 6.517   -17.929  1.00 51.59  ? 105 TYR A C   1 
ATOM   763   O O   . TYR A 1 102 ? -35.240 5.337   -18.111  1.00 51.16  ? 105 TYR A O   1 
ATOM   764   C CB  . TYR A 1 102 ? -36.480 8.121   -16.788  1.00 37.21  ? 105 TYR A CB  1 
ATOM   765   C CG  . TYR A 1 102 ? -37.743 7.395   -17.190  1.00 52.73  ? 105 TYR A CG  1 
ATOM   766   C CD1 . TYR A 1 102 ? -38.083 6.177   -16.614  1.00 51.54  ? 105 TYR A CD1 1 
ATOM   767   C CD2 . TYR A 1 102 ? -38.606 7.939   -18.133  1.00 51.65  ? 105 TYR A CD2 1 
ATOM   768   C CE1 . TYR A 1 102 ? -39.244 5.515   -16.977  1.00 52.75  ? 105 TYR A CE1 1 
ATOM   769   C CE2 . TYR A 1 102 ? -39.767 7.287   -18.499  1.00 53.71  ? 105 TYR A CE2 1 
ATOM   770   C CZ  . TYR A 1 102 ? -40.082 6.076   -17.918  1.00 51.83  ? 105 TYR A CZ  1 
ATOM   771   O OH  . TYR A 1 102 ? -41.238 5.424   -18.284  1.00 52.95  ? 105 TYR A OH  1 
ATOM   772   N N   . GLU A 1 103 ? -34.258 7.222   -18.853  1.00 49.93  ? 106 GLU A N   1 
ATOM   773   C CA  . GLU A 1 103 ? -33.988 6.642   -20.166  1.00 49.25  ? 106 GLU A CA  1 
ATOM   774   C C   . GLU A 1 103 ? -32.977 5.505   -20.079  1.00 49.25  ? 106 GLU A C   1 
ATOM   775   O O   . GLU A 1 103 ? -33.095 4.507   -20.799  1.00 51.99  ? 106 GLU A O   1 
ATOM   776   C CB  . GLU A 1 103 ? -33.504 7.720   -21.134  1.00 59.28  ? 106 GLU A CB  1 
ATOM   777   C CG  . GLU A 1 103 ? -34.498 8.849   -21.364  1.00 53.25  ? 106 GLU A CG  1 
ATOM   778   C CD  . GLU A 1 103 ? -34.484 9.876   -20.247  1.00 60.19  ? 106 GLU A CD  1 
ATOM   779   O OE1 . GLU A 1 103 ? -33.471 9.946   -19.519  1.00 66.20  ? 106 GLU A OE1 1 
ATOM   780   O OE2 . GLU A 1 103 ? -35.485 10.610  -20.094  1.00 64.74  ? 106 GLU A OE2 1 
ATOM   781   N N   . GLU A 1 104 ? -31.968 5.639   -19.215  1.00 48.07  ? 107 GLU A N   1 
ATOM   782   C CA  . GLU A 1 104 ? -31.021 4.544   -19.026  1.00 50.88  ? 107 GLU A CA  1 
ATOM   783   C C   . GLU A 1 104 ? -31.690 3.346   -18.365  1.00 47.83  ? 107 GLU A C   1 
ATOM   784   O O   . GLU A 1 104 ? -31.392 2.196   -18.707  1.00 43.08  ? 107 GLU A O   1 
ATOM   785   C CB  . GLU A 1 104 ? -29.821 5.019   -18.207  1.00 42.49  ? 107 GLU A CB  1 
ATOM   786   C CG  . GLU A 1 104 ? -28.848 5.877   -18.997  1.00 46.73  ? 107 GLU A CG  1 
ATOM   787   C CD  . GLU A 1 104 ? -28.071 5.083   -20.036  1.00 54.01  ? 107 GLU A CD  1 
ATOM   788   O OE1 . GLU A 1 104 ? -27.533 4.010   -19.690  1.00 51.13  ? 107 GLU A OE1 1 
ATOM   789   O OE2 . GLU A 1 104 ? -28.000 5.531   -21.201  1.00 52.06  ? 107 GLU A OE2 1 
ATOM   790   N N   . LEU A 1 105 ? -32.597 3.596   -17.417  1.00 48.40  ? 108 LEU A N   1 
ATOM   791   C CA  . LEU A 1 105 ? -33.342 2.506   -16.794  1.00 53.61  ? 108 LEU A CA  1 
ATOM   792   C C   . LEU A 1 105 ? -34.213 1.780   -17.811  1.00 51.90  ? 108 LEU A C   1 
ATOM   793   O O   . LEU A 1 105 ? -34.296 0.546   -17.802  1.00 54.21  ? 108 LEU A O   1 
ATOM   794   C CB  . LEU A 1 105 ? -34.193 3.045   -15.644  1.00 52.26  ? 108 LEU A CB  1 
ATOM   795   C CG  . LEU A 1 105 ? -35.129 2.047   -14.960  1.00 45.21  ? 108 LEU A CG  1 
ATOM   796   C CD1 . LEU A 1 105 ? -34.335 0.926   -14.309  1.00 43.91  ? 108 LEU A CD1 1 
ATOM   797   C CD2 . LEU A 1 105 ? -36.007 2.754   -13.937  1.00 50.82  ? 108 LEU A CD2 1 
ATOM   798   N N   . LYS A 1 106 ? -34.877 2.531   -18.695  1.00 51.25  ? 109 LYS A N   1 
ATOM   799   C CA  . LYS A 1 106 ? -35.709 1.910   -19.721  1.00 45.99  ? 109 LYS A CA  1 
ATOM   800   C C   . LYS A 1 106 ? -34.876 1.059   -20.671  1.00 59.94  ? 109 LYS A C   1 
ATOM   801   O O   . LYS A 1 106 ? -35.293 -0.039  -21.058  1.00 54.97  ? 109 LYS A O   1 
ATOM   802   C CB  . LYS A 1 106 ? -36.472 2.983   -20.496  1.00 50.47  ? 109 LYS A CB  1 
ATOM   803   C CG  . LYS A 1 106 ? -37.605 3.622   -19.723  1.00 45.94  ? 109 LYS A CG  1 
ATOM   804   C CD  . LYS A 1 106 ? -38.120 4.862   -20.433  1.00 50.93  ? 109 LYS A CD  1 
ATOM   805   C CE  . LYS A 1 106 ? -38.746 4.531   -21.774  1.00 68.13  ? 109 LYS A CE  1 
ATOM   806   N NZ  . LYS A 1 106 ? -39.368 5.735   -22.393  1.00 72.18  ? 109 LYS A NZ  1 
ATOM   807   N N   . HIS A 1 107 ? -33.699 1.552   -21.062  1.00 53.67  ? 110 HIS A N   1 
ATOM   808   C CA  . HIS A 1 107 ? -32.841 0.793   -21.966  1.00 52.62  ? 110 HIS A CA  1 
ATOM   809   C C   . HIS A 1 107 ? -32.388 -0.515  -21.329  1.00 51.53  ? 110 HIS A C   1 
ATOM   810   O O   . HIS A 1 107 ? -32.355 -1.558  -21.992  1.00 49.74  ? 110 HIS A O   1 
ATOM   811   C CB  . HIS A 1 107 ? -31.637 1.641   -22.378  1.00 45.39  ? 110 HIS A CB  1 
ATOM   812   C CG  . HIS A 1 107 ? -30.767 0.998   -23.412  1.00 59.46  ? 110 HIS A CG  1 
ATOM   813   N ND1 . HIS A 1 107 ? -31.124 0.917   -24.741  1.00 53.13  ? 110 HIS A ND1 1 
ATOM   814   C CD2 . HIS A 1 107 ? -29.553 0.404   -23.312  1.00 40.14  ? 110 HIS A CD2 1 
ATOM   815   C CE1 . HIS A 1 107 ? -30.168 0.305   -25.416  1.00 43.68  ? 110 HIS A CE1 1 
ATOM   816   N NE2 . HIS A 1 107 ? -29.204 -0.018  -24.573  1.00 55.52  ? 110 HIS A NE2 1 
ATOM   817   N N   . MET A 1 108 ? -32.039 -0.478  -20.040  1.00 56.27  ? 111 MET A N   1 
ATOM   818   C CA  . MET A 1 108 ? -31.615 -1.692  -19.348  1.00 60.13  ? 111 MET A CA  1 
ATOM   819   C C   . MET A 1 108 ? -32.736 -2.723  -19.295  1.00 50.38  ? 111 MET A C   1 
ATOM   820   O O   . MET A 1 108 ? -32.494 -3.925  -19.456  1.00 47.60  ? 111 MET A O   1 
ATOM   821   C CB  . MET A 1 108 ? -31.138 -1.354  -17.935  1.00 55.70  ? 111 MET A CB  1 
ATOM   822   C CG  . MET A 1 108 ? -30.968 -2.575  -17.044  1.00 57.81  ? 111 MET A CG  1 
ATOM   823   S SD  . MET A 1 108 ? -31.140 -2.198  -15.289  1.00 84.19  ? 111 MET A SD  1 
ATOM   824   C CE  . MET A 1 108 ? -29.498 -1.596  -14.908  1.00 65.65  ? 111 MET A CE  1 
ATOM   825   N N   . LEU A 1 109 ? -33.970 -2.272  -19.075  1.00 49.09  ? 112 LEU A N   1 
ATOM   826   C CA  . LEU A 1 109 ? -35.114 -3.168  -18.957  1.00 51.13  ? 112 LEU A CA  1 
ATOM   827   C C   . LEU A 1 109 ? -35.698 -3.577  -20.304  1.00 50.86  ? 112 LEU A C   1 
ATOM   828   O O   . LEU A 1 109 ? -36.713 -4.281  -20.327  1.00 48.87  ? 112 LEU A O   1 
ATOM   829   C CB  . LEU A 1 109 ? -36.205 -2.511  -18.109  1.00 49.58  ? 112 LEU A CB  1 
ATOM   830   C CG  . LEU A 1 109 ? -35.869 -2.239  -16.643  1.00 55.65  ? 112 LEU A CG  1 
ATOM   831   C CD1 . LEU A 1 109 ? -36.928 -1.348  -16.026  1.00 48.72  ? 112 LEU A CD1 1 
ATOM   832   C CD2 . LEU A 1 109 ? -35.755 -3.543  -15.873  1.00 60.65  ? 112 LEU A CD2 1 
ATOM   833   N N   . SER A 1 110 ? -35.098 -3.148  -21.417  1.00 45.00  ? 113 SER A N   1 
ATOM   834   C CA  . SER A 1 110 ? -35.681 -3.427  -22.726  1.00 55.70  ? 113 SER A CA  1 
ATOM   835   C C   . SER A 1 110 ? -35.726 -4.925  -23.010  1.00 56.46  ? 113 SER A C   1 
ATOM   836   O O   . SER A 1 110 ? -36.721 -5.431  -23.541  1.00 60.61  ? 113 SER A O   1 
ATOM   837   C CB  . SER A 1 110 ? -34.904 -2.685  -23.814  1.00 47.65  ? 113 SER A CB  1 
ATOM   838   O OG  . SER A 1 110 ? -33.539 -3.067  -23.817  1.00 59.79  ? 113 SER A OG  1 
ATOM   839   N N   . ARG A 1 111 ? -34.664 -5.652  -22.666  1.00 61.12  ? 114 ARG A N   1 
ATOM   840   C CA  . ARG A 1 111 ? -34.638 -7.107  -22.776  1.00 51.30  ? 114 ARG A CA  1 
ATOM   841   C C   . ARG A 1 111 ? -34.117 -7.684  -21.468  1.00 55.44  ? 114 ARG A C   1 
ATOM   842   O O   . ARG A 1 111 ? -32.957 -7.460  -21.108  1.00 54.59  ? 114 ARG A O   1 
ATOM   843   C CB  . ARG A 1 111 ? -33.774 -7.571  -23.953  1.00 52.48  ? 114 ARG A CB  1 
ATOM   844   C CG  . ARG A 1 111 ? -33.365 -9.034  -23.861  1.00 54.37  ? 114 ARG A CG  1 
ATOM   845   C CD  . ARG A 1 111 ? -33.189 -9.677  -25.226  1.00 66.53  ? 114 ARG A CD  1 
ATOM   846   N NE  . ARG A 1 111 ? -32.145 -9.042  -26.020  1.00 73.59  ? 114 ARG A NE  1 
ATOM   847   C CZ  . ARG A 1 111 ? -31.632 -9.561  -27.127  1.00 77.34  ? 114 ARG A CZ  1 
ATOM   848   N NH1 . ARG A 1 111 ? -32.030 -10.736 -27.588  1.00 70.97  ? 114 ARG A NH1 1 
ATOM   849   N NH2 . ARG A 1 111 ? -30.691 -8.889  -27.785  1.00 71.23  ? 114 ARG A NH2 1 
ATOM   850   N N   . ILE A 1 112 ? -34.969 -8.431  -20.769  1.00 51.22  ? 115 ILE A N   1 
ATOM   851   C CA  . ILE A 1 112 ? -34.667 -8.955  -19.442  1.00 53.89  ? 115 ILE A CA  1 
ATOM   852   C C   . ILE A 1 112 ? -34.802 -10.470 -19.473  1.00 60.97  ? 115 ILE A C   1 
ATOM   853   O O   . ILE A 1 112 ? -35.829 -10.998 -19.915  1.00 54.02  ? 115 ILE A O   1 
ATOM   854   C CB  . ILE A 1 112 ? -35.588 -8.342  -18.372  1.00 54.20  ? 115 ILE A CB  1 
ATOM   855   C CG1 . ILE A 1 112 ? -35.259 -6.860  -18.179  1.00 57.06  ? 115 ILE A CG1 1 
ATOM   856   C CG2 . ILE A 1 112 ? -35.467 -9.100  -17.062  1.00 57.12  ? 115 ILE A CG2 1 
ATOM   857   C CD1 . ILE A 1 112 ? -33.822 -6.603  -17.765  1.00 59.56  ? 115 ILE A CD1 1 
ATOM   858   N N   . ASN A 1 113 ? -33.762 -11.166 -19.007  1.00 59.98  ? 116 ASN A N   1 
ATOM   859   C CA  . ASN A 1 113 ? -33.782 -12.625 -18.992  1.00 55.04  ? 116 ASN A CA  1 
ATOM   860   C C   . ASN A 1 113 ? -34.630 -13.173 -17.847  1.00 63.72  ? 116 ASN A C   1 
ATOM   861   O O   . ASN A 1 113 ? -35.296 -14.201 -18.006  1.00 72.22  ? 116 ASN A O   1 
ATOM   862   C CB  . ASN A 1 113 ? -32.354 -13.167 -18.910  1.00 64.52  ? 116 ASN A CB  1 
ATOM   863   C CG  . ASN A 1 113 ? -32.300 -14.679 -18.994  1.00 73.76  ? 116 ASN A CG  1 
ATOM   864   O OD1 . ASN A 1 113 ? -31.931 -15.353 -18.033  1.00 83.84  ? 116 ASN A OD1 1 
ATOM   865   N ND2 . ASN A 1 113 ? -32.677 -15.220 -20.148  1.00 84.76  ? 116 ASN A ND2 1 
ATOM   866   N N   . HIS A 1 114 ? -34.611 -12.516 -16.688  1.00 63.08  ? 117 HIS A N   1 
ATOM   867   C CA  . HIS A 1 114 ? -35.438 -12.938 -15.564  1.00 59.38  ? 117 HIS A CA  1 
ATOM   868   C C   . HIS A 1 114 ? -35.842 -11.724 -14.743  1.00 57.81  ? 117 HIS A C   1 
ATOM   869   O O   . HIS A 1 114 ? -34.998 -10.887 -14.410  1.00 65.39  ? 117 HIS A O   1 
ATOM   870   C CB  . HIS A 1 114 ? -34.714 -13.955 -14.676  1.00 67.75  ? 117 HIS A CB  1 
ATOM   871   C CG  . HIS A 1 114 ? -35.534 -14.424 -13.514  1.00 71.33  ? 117 HIS A CG  1 
ATOM   872   N ND1 . HIS A 1 114 ? -35.204 -14.141 -12.206  1.00 73.99  ? 117 HIS A ND1 1 
ATOM   873   C CD2 . HIS A 1 114 ? -36.680 -15.144 -13.465  1.00 64.12  ? 117 HIS A CD2 1 
ATOM   874   C CE1 . HIS A 1 114 ? -36.106 -14.675 -11.401  1.00 73.47  ? 117 HIS A CE1 1 
ATOM   875   N NE2 . HIS A 1 114 ? -37.013 -15.288 -12.140  1.00 69.32  ? 117 HIS A NE2 1 
ATOM   876   N N   . PHE A 1 115 ? -37.129 -11.646 -14.412  1.00 59.93  ? 118 PHE A N   1 
ATOM   877   C CA  . PHE A 1 115 ? -37.701 -10.535 -13.664  1.00 63.18  ? 118 PHE A CA  1 
ATOM   878   C C   . PHE A 1 115 ? -38.680 -11.108 -12.651  1.00 59.50  ? 118 PHE A C   1 
ATOM   879   O O   . PHE A 1 115 ? -39.491 -11.971 -12.999  1.00 72.46  ? 118 PHE A O   1 
ATOM   880   C CB  . PHE A 1 115 ? -38.405 -9.556  -14.611  1.00 55.67  ? 118 PHE A CB  1 
ATOM   881   C CG  . PHE A 1 115 ? -38.546 -8.162  -14.067  1.00 58.96  ? 118 PHE A CG  1 
ATOM   882   C CD1 . PHE A 1 115 ? -37.430 -7.367  -13.861  1.00 56.50  ? 118 PHE A CD1 1 
ATOM   883   C CD2 . PHE A 1 115 ? -39.799 -7.636  -13.795  1.00 59.95  ? 118 PHE A CD2 1 
ATOM   884   C CE1 . PHE A 1 115 ? -37.561 -6.080  -13.371  1.00 58.52  ? 118 PHE A CE1 1 
ATOM   885   C CE2 . PHE A 1 115 ? -39.936 -6.349  -13.309  1.00 56.56  ? 118 PHE A CE2 1 
ATOM   886   C CZ  . PHE A 1 115 ? -38.817 -5.570  -13.097  1.00 60.72  ? 118 PHE A CZ  1 
ATOM   887   N N   . GLU A 1 116 ? -38.602 -10.645 -11.403  1.00 56.48  ? 119 GLU A N   1 
ATOM   888   C CA  . GLU A 1 116 ? -39.457 -11.190 -10.349  1.00 64.61  ? 119 GLU A CA  1 
ATOM   889   C C   . GLU A 1 116 ? -39.587 -10.176 -9.225   1.00 60.92  ? 119 GLU A C   1 
ATOM   890   O O   . GLU A 1 116 ? -38.580 -9.789  -8.622   1.00 61.26  ? 119 GLU A O   1 
ATOM   891   C CB  . GLU A 1 116 ? -38.890 -12.510 -9.819   1.00 66.35  ? 119 GLU A CB  1 
ATOM   892   C CG  . GLU A 1 116 ? -39.700 -13.124 -8.684   1.00 70.99  ? 119 GLU A CG  1 
ATOM   893   C CD  . GLU A 1 116 ? -39.098 -14.419 -8.170   1.00 78.09  ? 119 GLU A CD  1 
ATOM   894   O OE1 . GLU A 1 116 ? -38.147 -14.927 -8.800   1.00 87.78  ? 119 GLU A OE1 1 
ATOM   895   O OE2 . GLU A 1 116 ? -39.576 -14.927 -7.134   1.00 84.44  ? 119 GLU A OE2 1 
ATOM   896   N N   . LYS A 1 117 ? -40.818 -9.761  -8.930   1.00 49.01  ? 120 LYS A N   1 
ATOM   897   C CA  . LYS A 1 117 ? -41.063 -8.839  -7.830   1.00 53.34  ? 120 LYS A CA  1 
ATOM   898   C C   . LYS A 1 117 ? -41.055 -9.591  -6.505   1.00 61.75  ? 120 LYS A C   1 
ATOM   899   O O   . LYS A 1 117 ? -41.745 -10.603 -6.353   1.00 69.85  ? 120 LYS A O   1 
ATOM   900   C CB  . LYS A 1 117 ? -42.397 -8.114  -8.017   1.00 57.04  ? 120 LYS A CB  1 
ATOM   901   C CG  . LYS A 1 117 ? -42.666 -7.059  -6.947   1.00 62.22  ? 120 LYS A CG  1 
ATOM   902   C CD  . LYS A 1 117 ? -43.844 -6.157  -7.295   1.00 57.45  ? 120 LYS A CD  1 
ATOM   903   C CE  . LYS A 1 117 ? -45.176 -6.812  -6.970   1.00 82.52  ? 120 LYS A CE  1 
ATOM   904   N NZ  . LYS A 1 117 ? -46.289 -5.819  -6.972   1.00 82.36  ? 120 LYS A NZ  1 
ATOM   905   N N   . ILE A 1 118 ? -40.271 -9.094  -5.547   1.00 64.60  ? 121 ILE A N   1 
ATOM   906   C CA  . ILE A 1 118 ? -40.210 -9.659  -4.207   1.00 56.96  ? 121 ILE A CA  1 
ATOM   907   C C   . ILE A 1 118 ? -40.394 -8.535  -3.198   1.00 61.05  ? 121 ILE A C   1 
ATOM   908   O O   . ILE A 1 118 ? -40.129 -7.364  -3.477   1.00 71.94  ? 121 ILE A O   1 
ATOM   909   C CB  . ILE A 1 118 ? -38.887 -10.409 -3.929   1.00 64.44  ? 121 ILE A CB  1 
ATOM   910   C CG1 . ILE A 1 118 ? -37.727 -9.421  -3.786   1.00 61.45  ? 121 ILE A CG1 1 
ATOM   911   C CG2 . ILE A 1 118 ? -38.597 -11.423 -5.026   1.00 66.58  ? 121 ILE A CG2 1 
ATOM   912   C CD1 . ILE A 1 118 ? -36.450 -10.051 -3.276   1.00 72.47  ? 121 ILE A CD1 1 
ATOM   913   N N   . GLN A 1 119 ? -40.856 -8.910  -2.009   1.00 69.09  ? 122 GLN A N   1 
ATOM   914   C CA  . GLN A 1 119 ? -41.023 -7.972  -0.907   1.00 68.74  ? 122 GLN A CA  1 
ATOM   915   C C   . GLN A 1 119 ? -39.750 -7.963  -0.070   1.00 73.31  ? 122 GLN A C   1 
ATOM   916   O O   . GLN A 1 119 ? -39.329 -9.009  0.437    1.00 65.03  ? 122 GLN A O   1 
ATOM   917   C CB  . GLN A 1 119 ? -42.229 -8.354  -0.051   1.00 59.84  ? 122 GLN A CB  1 
ATOM   918   C CG  . GLN A 1 119 ? -42.438 -7.459  1.159    1.00 79.17  ? 122 GLN A CG  1 
ATOM   919   C CD  . GLN A 1 119 ? -43.575 -7.932  2.043    1.00 75.64  ? 122 GLN A CD  1 
ATOM   920   O OE1 . GLN A 1 119 ? -44.607 -7.271  2.154    1.00 69.29  ? 122 GLN A OE1 1 
ATOM   921   N NE2 . GLN A 1 119 ? -43.389 -9.083  2.681    1.00 77.86  ? 122 GLN A NE2 1 
ATOM   922   N N   . ILE A 1 120 ? -39.139 -6.790  0.073    1.00 63.44  ? 123 ILE A N   1 
ATOM   923   C CA  . ILE A 1 120 ? -37.904 -6.640  0.826    1.00 58.64  ? 123 ILE A CA  1 
ATOM   924   C C   . ILE A 1 120 ? -38.141 -5.957  2.167    1.00 54.14  ? 123 ILE A C   1 
ATOM   925   O O   . ILE A 1 120 ? -37.484 -6.286  3.157    1.00 69.61  ? 123 ILE A O   1 
ATOM   926   C CB  . ILE A 1 120 ? -36.837 -5.884  0.001    1.00 70.36  ? 123 ILE A CB  1 
ATOM   927   C CG1 . ILE A 1 120 ? -37.337 -4.494  -0.406   1.00 52.53  ? 123 ILE A CG1 1 
ATOM   928   C CG2 . ILE A 1 120 ? -36.452 -6.689  -1.227   1.00 59.82  ? 123 ILE A CG2 1 
ATOM   929   C CD1 . ILE A 1 120 ? -36.256 -3.604  -0.980   1.00 55.57  ? 123 ILE A CD1 1 
ATOM   930   N N   . ILE A 1 121 ? -39.070 -5.007  2.220    1.00 60.12  ? 124 ILE A N   1 
ATOM   931   C CA  . ILE A 1 121 ? -39.376 -4.284  3.451    1.00 57.02  ? 124 ILE A CA  1 
ATOM   932   C C   . ILE A 1 121 ? -40.883 -4.313  3.676    1.00 66.30  ? 124 ILE A C   1 
ATOM   933   O O   . ILE A 1 121 ? -41.611 -3.491  3.100    1.00 73.26  ? 124 ILE A O   1 
ATOM   934   C CB  . ILE A 1 121 ? -38.848 -2.842  3.399    1.00 59.27  ? 124 ILE A CB  1 
ATOM   935   C CG1 . ILE A 1 121 ? -37.332 -2.835  3.183    1.00 57.13  ? 124 ILE A CG1 1 
ATOM   936   C CG2 . ILE A 1 121 ? -39.203 -2.104  4.677    1.00 58.47  ? 124 ILE A CG2 1 
ATOM   937   C CD1 . ILE A 1 121 ? -36.777 -1.485  2.785    1.00 61.51  ? 124 ILE A CD1 1 
ATOM   938   N N   . PRO A 1 122 ? -41.395 -5.238  4.484    1.00 68.39  ? 125 PRO A N   1 
ATOM   939   C CA  . PRO A 1 122 ? -42.838 -5.277  4.739    1.00 66.24  ? 125 PRO A CA  1 
ATOM   940   C C   . PRO A 1 122 ? -43.297 -4.061  5.529    1.00 63.19  ? 125 PRO A C   1 
ATOM   941   O O   . PRO A 1 122 ? -42.516 -3.388  6.204    1.00 74.52  ? 125 PRO A O   1 
ATOM   942   C CB  . PRO A 1 122 ? -43.024 -6.568  5.544    1.00 68.98  ? 125 PRO A CB  1 
ATOM   943   C CG  . PRO A 1 122 ? -41.694 -6.809  6.180    1.00 77.38  ? 125 PRO A CG  1 
ATOM   944   C CD  . PRO A 1 122 ? -40.673 -6.306  5.197    1.00 67.48  ? 125 PRO A CD  1 
ATOM   945   N N   . LYS A 1 123 A -44.598 -3.781  5.426    1.00 66.98  ? 125 LYS A N   1 
ATOM   946   C CA  . LYS A 1 123 A -45.168 -2.634  6.125    1.00 68.56  ? 125 LYS A CA  1 
ATOM   947   C C   . LYS A 1 123 A -45.090 -2.779  7.639    1.00 80.09  ? 125 LYS A C   1 
ATOM   948   O O   . LYS A 1 123 A -45.233 -1.780  8.354    1.00 75.25  ? 125 LYS A O   1 
ATOM   949   C CB  . LYS A 1 123 A -46.617 -2.421  5.689    1.00 68.25  ? 125 LYS A CB  1 
ATOM   950   C CG  . LYS A 1 123 A -46.757 -1.710  4.353    1.00 73.25  ? 125 LYS A CG  1 
ATOM   951   C CD  . LYS A 1 123 A -48.214 -1.465  4.006    1.00 73.89  ? 125 LYS A CD  1 
ATOM   952   C CE  . LYS A 1 123 A -48.374 -0.195  3.185    1.00 92.90  ? 125 LYS A CE  1 
ATOM   953   N NZ  . LYS A 1 123 A -49.781 0.005   2.734    1.00 95.23  ? 125 LYS A NZ  1 
ATOM   954   N N   . SER A 1 124 B -44.866 -3.993  8.145    1.00 77.22  ? 125 SER A N   1 
ATOM   955   C CA  . SER A 1 124 B -44.672 -4.185  9.576    1.00 79.83  ? 125 SER A CA  1 
ATOM   956   C C   . SER A 1 124 B -43.336 -3.641  10.067   1.00 76.36  ? 125 SER A C   1 
ATOM   957   O O   . SER A 1 124 B -43.123 -3.576  11.282   1.00 86.18  ? 125 SER A O   1 
ATOM   958   C CB  . SER A 1 124 B -44.787 -5.670  9.927    1.00 83.59  ? 125 SER A CB  1 
ATOM   959   O OG  . SER A 1 124 B -43.789 -6.433  9.269    1.00 82.67  ? 125 SER A OG  1 
ATOM   960   N N   . SER A 1 125 ? -42.442 -3.247  9.161    1.00 75.71  ? 126 SER A N   1 
ATOM   961   C CA  . SER A 1 125 ? -41.122 -2.753  9.530    1.00 64.24  ? 126 SER A CA  1 
ATOM   962   C C   . SER A 1 125 ? -41.128 -1.291  9.955    1.00 62.31  ? 126 SER A C   1 
ATOM   963   O O   . SER A 1 125 ? -40.073 -0.773  10.338   1.00 64.35  ? 126 SER A O   1 
ATOM   964   C CB  . SER A 1 125 ? -40.145 -2.943  8.366    1.00 71.12  ? 126 SER A CB  1 
ATOM   965   O OG  . SER A 1 125 ? -40.077 -4.302  7.970    1.00 76.65  ? 126 SER A OG  1 
ATOM   966   N N   . TRP A 1 126 ? -42.278 -0.617  9.906    1.00 60.85  ? 127 TRP A N   1 
ATOM   967   C CA  . TRP A 1 126 ? -42.398 0.790   10.285   1.00 68.71  ? 127 TRP A CA  1 
ATOM   968   C C   . TRP A 1 126 ? -43.369 0.916   11.457   1.00 74.48  ? 127 TRP A C   1 
ATOM   969   O O   . TRP A 1 126 ? -44.471 1.463   11.308   1.00 69.76  ? 127 TRP A O   1 
ATOM   970   C CB  . TRP A 1 126 ? -42.870 1.637   9.105    1.00 67.51  ? 127 TRP A CB  1 
ATOM   971   C CG  . TRP A 1 126 ? -42.227 1.274   7.800    1.00 74.43  ? 127 TRP A CG  1 
ATOM   972   C CD1 . TRP A 1 126 ? -42.774 0.532   6.792    1.00 61.16  ? 127 TRP A CD1 1 
ATOM   973   C CD2 . TRP A 1 126 ? -40.913 1.637   7.363    1.00 74.60  ? 127 TRP A CD2 1 
ATOM   974   N NE1 . TRP A 1 126 ? -41.882 0.413   5.754    1.00 75.33  ? 127 TRP A NE1 1 
ATOM   975   C CE2 . TRP A 1 126 ? -40.732 1.083   6.080    1.00 69.94  ? 127 TRP A CE2 1 
ATOM   976   C CE3 . TRP A 1 126 ? -39.873 2.377   7.931    1.00 74.19  ? 127 TRP A CE3 1 
ATOM   977   C CZ2 . TRP A 1 126 ? -39.553 1.246   5.359    1.00 55.59  ? 127 TRP A CZ2 1 
ATOM   978   C CZ3 . TRP A 1 126 ? -38.704 2.537   7.212    1.00 65.32  ? 127 TRP A CZ3 1 
ATOM   979   C CH2 . TRP A 1 126 ? -38.554 1.975   5.941    1.00 59.55  ? 127 TRP A CH2 1 
ATOM   980   N N   . PRO A 1 127 ? -42.989 0.425   12.642   1.00 71.62  ? 128 PRO A N   1 
ATOM   981   C CA  . PRO A 1 127 ? -43.927 0.466   13.774   1.00 74.85  ? 128 PRO A CA  1 
ATOM   982   C C   . PRO A 1 127 ? -44.192 1.867   14.296   1.00 69.57  ? 128 PRO A C   1 
ATOM   983   O O   . PRO A 1 127 ? -45.295 2.129   14.792   1.00 74.92  ? 128 PRO A O   1 
ATOM   984   C CB  . PRO A 1 127 ? -43.235 -0.407  14.830   1.00 64.75  ? 128 PRO A CB  1 
ATOM   985   C CG  . PRO A 1 127 ? -41.787 -0.256  14.530   1.00 70.96  ? 128 PRO A CG  1 
ATOM   986   C CD  . PRO A 1 127 ? -41.683 -0.137  13.031   1.00 68.85  ? 128 PRO A CD  1 
ATOM   987   N N   . ASN A 1 128 ? -43.223 2.775   14.198   1.00 81.61  ? 129 ASN A N   1 
ATOM   988   C CA  . ASN A 1 128 ? -43.346 4.117   14.750   1.00 69.20  ? 129 ASN A CA  1 
ATOM   989   C C   . ASN A 1 128 ? -43.783 5.145   13.714   1.00 64.86  ? 129 ASN A C   1 
ATOM   990   O O   . ASN A 1 128 ? -43.724 6.347   13.990   1.00 67.88  ? 129 ASN A O   1 
ATOM   991   C CB  . ASN A 1 128 ? -42.023 4.550   15.383   1.00 73.38  ? 129 ASN A CB  1 
ATOM   992   C CG  . ASN A 1 128 ? -41.545 3.589   16.455   1.00 85.99  ? 129 ASN A CG  1 
ATOM   993   O OD1 . ASN A 1 128 ? -42.347 2.925   17.114   1.00 74.59  ? 129 ASN A OD1 1 
ATOM   994   N ND2 . ASN A 1 128 ? -40.231 3.511   16.637   1.00 79.71  ? 129 ASN A ND2 1 
ATOM   995   N N   . HIS A 1 129 ? -44.212 4.707   12.532   1.00 56.80  ? 130 HIS A N   1 
ATOM   996   C CA  . HIS A 1 129 ? -44.649 5.609   11.478   1.00 70.77  ? 130 HIS A CA  1 
ATOM   997   C C   . HIS A 1 129 ? -45.970 5.127   10.896   1.00 66.67  ? 130 HIS A C   1 
ATOM   998   O O   . HIS A 1 129 ? -46.251 3.926   10.861   1.00 74.55  ? 130 HIS A O   1 
ATOM   999   C CB  . HIS A 1 129 ? -43.600 5.721   10.360   1.00 68.16  ? 130 HIS A CB  1 
ATOM   1000  C CG  . HIS A 1 129 ? -42.258 6.183   10.835   1.00 58.66  ? 130 HIS A CG  1 
ATOM   1001  N ND1 . HIS A 1 129 ? -41.319 5.323   11.362   1.00 58.50  ? 130 HIS A ND1 1 
ATOM   1002  C CD2 . HIS A 1 129 ? -41.699 7.417   10.869   1.00 59.17  ? 130 HIS A CD2 1 
ATOM   1003  C CE1 . HIS A 1 129 ? -40.238 6.006   11.697   1.00 60.52  ? 130 HIS A CE1 1 
ATOM   1004  N NE2 . HIS A 1 129 ? -40.443 7.279   11.408   1.00 59.42  ? 130 HIS A NE2 1 
ATOM   1005  N N   . GLU A 1 130 ? -46.779 6.081   10.440   1.00 57.93  ? 131 GLU A N   1 
ATOM   1006  C CA  . GLU A 1 130 ? -48.050 5.765   9.803    1.00 68.91  ? 131 GLU A CA  1 
ATOM   1007  C C   . GLU A 1 130 ? -47.811 5.244   8.391    1.00 74.69  ? 131 GLU A C   1 
ATOM   1008  O O   . GLU A 1 130 ? -47.095 5.870   7.602    1.00 74.47  ? 131 GLU A O   1 
ATOM   1009  C CB  . GLU A 1 130 ? -48.948 7.002   9.767    1.00 72.90  ? 131 GLU A CB  1 
ATOM   1010  C CG  . GLU A 1 130 ? -50.272 6.791   9.047    1.00 84.64  ? 131 GLU A CG  1 
ATOM   1011  C CD  . GLU A 1 130 ? -51.196 5.836   9.779    1.00 88.12  ? 131 GLU A CD  1 
ATOM   1012  O OE1 . GLU A 1 130 ? -51.051 5.688   11.011   1.00 88.25  ? 131 GLU A OE1 1 
ATOM   1013  O OE2 . GLU A 1 130 ? -52.070 5.232   9.121    1.00 83.65  ? 131 GLU A OE2 1 
ATOM   1014  N N   . THR A 1 131 ? -48.417 4.100   8.070    1.00 81.75  ? 132 THR A N   1 
ATOM   1015  C CA  . THR A 1 131 ? -48.199 3.442   6.787    1.00 65.16  ? 132 THR A CA  1 
ATOM   1016  C C   . THR A 1 131 ? -49.481 3.262   5.981    1.00 70.47  ? 132 THR A C   1 
ATOM   1017  O O   . THR A 1 131 ? -49.484 2.493   5.012    1.00 78.39  ? 132 THR A O   1 
ATOM   1018  C CB  . THR A 1 131 ? -47.533 2.078   6.993    1.00 72.45  ? 132 THR A CB  1 
ATOM   1019  O OG1 . THR A 1 131 ? -48.479 1.165   7.562    1.00 79.02  ? 132 THR A OG1 1 
ATOM   1020  C CG2 . THR A 1 131 ? -46.334 2.201   7.923    1.00 61.20  ? 132 THR A CG2 1 
ATOM   1021  N N   . SER A 1 132 ? -50.568 3.943   6.347    1.00 67.61  ? 133 SER A N   1 
ATOM   1022  C CA  . SER A 1 132 ? -51.824 3.817   5.621    1.00 69.20  ? 133 SER A CA  1 
ATOM   1023  C C   . SER A 1 132 ? -52.452 5.153   5.251    1.00 65.92  ? 133 SER A C   1 
ATOM   1024  O O   . SER A 1 132 ? -53.537 5.163   4.658    1.00 74.66  ? 133 SER A O   1 
ATOM   1025  C CB  . SER A 1 132 ? -52.838 2.994   6.432    1.00 79.78  ? 133 SER A CB  1 
ATOM   1026  O OG  . SER A 1 132 ? -53.329 3.732   7.537    1.00 82.68  ? 133 SER A OG  1 
ATOM   1027  N N   . LEU A 1 133 A -51.819 6.274   5.588    1.00 67.25  ? 133 LEU A N   1 
ATOM   1028  C CA  . LEU A 1 133 A -52.320 7.589   5.215    1.00 81.10  ? 133 LEU A CA  1 
ATOM   1029  C C   . LEU A 1 133 A -51.637 8.156   3.978    1.00 69.40  ? 133 LEU A C   1 
ATOM   1030  O O   . LEU A 1 133 A -52.031 9.227   3.509    1.00 69.76  ? 133 LEU A O   1 
ATOM   1031  C CB  . LEU A 1 133 A -52.165 8.567   6.386    1.00 63.41  ? 133 LEU A CB  1 
ATOM   1032  C CG  . LEU A 1 133 A -53.410 8.805   7.247    1.00 73.66  ? 133 LEU A CG  1 
ATOM   1033  C CD1 . LEU A 1 133 A -54.044 7.489   7.676    1.00 74.53  ? 133 LEU A CD1 1 
ATOM   1034  C CD2 . LEU A 1 133 A -53.064 9.652   8.461    1.00 69.06  ? 133 LEU A CD2 1 
ATOM   1035  N N   . GLY A 1 134 ? -50.643 7.460   3.430    1.00 66.45  ? 134 GLY A N   1 
ATOM   1036  C CA  . GLY A 1 134 ? -49.919 7.949   2.273    1.00 55.43  ? 134 GLY A CA  1 
ATOM   1037  C C   . GLY A 1 134 ? -50.656 7.737   0.968    1.00 55.01  ? 134 GLY A C   1 
ATOM   1038  O O   . GLY A 1 134 ? -50.276 6.882   0.162    1.00 55.92  ? 134 GLY A O   1 
ATOM   1039  N N   . VAL A 1 135 ? -51.718 8.514   0.749    1.00 51.35  ? 135 VAL A N   1 
ATOM   1040  C CA  . VAL A 1 135 ? -52.549 8.402   -0.440   1.00 55.45  ? 135 VAL A CA  1 
ATOM   1041  C C   . VAL A 1 135 ? -52.748 9.791   -1.030   1.00 59.53  ? 135 VAL A C   1 
ATOM   1042  O O   . VAL A 1 135 ? -52.494 10.811  -0.385   1.00 55.02  ? 135 VAL A O   1 
ATOM   1043  C CB  . VAL A 1 135 ? -53.915 7.746   -0.142   1.00 67.15  ? 135 VAL A CB  1 
ATOM   1044  C CG1 . VAL A 1 135 ? -53.724 6.322   0.359    1.00 57.82  ? 135 VAL A CG1 1 
ATOM   1045  C CG2 . VAL A 1 135 ? -54.688 8.577   0.871    1.00 56.49  ? 135 VAL A CG2 1 
ATOM   1046  N N   . SER A 1 136 ? -53.212 9.820   -2.277   1.00 59.05  ? 136 SER A N   1 
ATOM   1047  C CA  . SER A 1 136 ? -53.399 11.077  -2.985   1.00 68.82  ? 136 SER A CA  1 
ATOM   1048  C C   . SER A 1 136 ? -54.538 10.934  -3.983   1.00 56.21  ? 136 SER A C   1 
ATOM   1049  O O   . SER A 1 136 ? -54.750 9.862   -4.555   1.00 64.15  ? 136 SER A O   1 
ATOM   1050  C CB  . SER A 1 136 ? -52.116 11.507  -3.708   1.00 70.29  ? 136 SER A CB  1 
ATOM   1051  O OG  . SER A 1 136 ? -52.342 12.655  -4.511   1.00 67.53  ? 136 SER A OG  1 
ATOM   1052  N N   . ALA A 1 137 ? -55.267 12.034  -4.188   1.00 66.81  ? 137 ALA A N   1 
ATOM   1053  C CA  . ALA A 1 137 ? -56.271 12.068  -5.244   1.00 72.77  ? 137 ALA A CA  1 
ATOM   1054  C C   . ALA A 1 137 ? -55.639 12.084  -6.629   1.00 76.51  ? 137 ALA A C   1 
ATOM   1055  O O   . ALA A 1 137 ? -56.335 11.834  -7.618   1.00 69.75  ? 137 ALA A O   1 
ATOM   1056  C CB  . ALA A 1 137 ? -57.182 13.284  -5.070   1.00 60.13  ? 137 ALA A CB  1 
ATOM   1057  N N   . ALA A 1 138 ? -54.339 12.379  -6.719   1.00 76.08  ? 138 ALA A N   1 
ATOM   1058  C CA  . ALA A 1 138 ? -53.634 12.287  -7.991   1.00 63.86  ? 138 ALA A CA  1 
ATOM   1059  C C   . ALA A 1 138 ? -53.469 10.845  -8.451   1.00 61.42  ? 138 ALA A C   1 
ATOM   1060  O O   . ALA A 1 138 ? -53.259 10.610  -9.645   1.00 71.29  ? 138 ALA A O   1 
ATOM   1061  C CB  . ALA A 1 138 ? -52.266 12.960  -7.883   1.00 62.77  ? 138 ALA A CB  1 
ATOM   1062  N N   . CYS A 1 139 ? -53.564 9.878   -7.534   1.00 66.39  ? 139 CYS A N   1 
ATOM   1063  C CA  . CYS A 1 139 ? -53.465 8.454   -7.844   1.00 74.24  ? 139 CYS A CA  1 
ATOM   1064  C C   . CYS A 1 139 ? -54.789 7.798   -7.471   1.00 72.06  ? 139 CYS A C   1 
ATOM   1065  O O   . CYS A 1 139 ? -54.887 7.119   -6.438   1.00 61.95  ? 139 CYS A O   1 
ATOM   1066  C CB  . CYS A 1 139 ? -52.301 7.799   -7.101   1.00 60.91  ? 139 CYS A CB  1 
ATOM   1067  S SG  . CYS A 1 139 ? -50.695 8.552   -7.425   1.00 80.51  ? 139 CYS A SG  1 
ATOM   1068  N N   . PRO A 1 140 ? -55.829 7.979   -8.281   1.00 72.84  ? 140 PRO A N   1 
ATOM   1069  C CA  . PRO A 1 140 ? -57.131 7.396   -7.948   1.00 72.48  ? 140 PRO A CA  1 
ATOM   1070  C C   . PRO A 1 140 ? -57.118 5.886   -8.119   1.00 61.91  ? 140 PRO A C   1 
ATOM   1071  O O   . PRO A 1 140 ? -56.308 5.320   -8.855   1.00 87.48  ? 140 PRO A O   1 
ATOM   1072  C CB  . PRO A 1 140 ? -58.092 8.054   -8.948   1.00 66.06  ? 140 PRO A CB  1 
ATOM   1073  C CG  . PRO A 1 140 ? -57.291 9.132   -9.641   1.00 67.68  ? 140 PRO A CG  1 
ATOM   1074  C CD  . PRO A 1 140 ? -55.868 8.691   -9.566   1.00 69.37  ? 140 PRO A CD  1 
ATOM   1075  N N   . TYR A 1 141 ? -58.036 5.232   -7.411   1.00 73.67  ? 141 TYR A N   1 
ATOM   1076  C CA  . TYR A 1 141 ? -58.277 3.807   -7.626   1.00 84.63  ? 141 TYR A CA  1 
ATOM   1077  C C   . TYR A 1 141 ? -59.680 3.485   -7.136   1.00 77.50  ? 141 TYR A C   1 
ATOM   1078  O O   . TYR A 1 141 ? -59.942 3.554   -5.930   1.00 83.44  ? 141 TYR A O   1 
ATOM   1079  C CB  . TYR A 1 141 ? -57.237 2.948   -6.916   1.00 74.34  ? 141 TYR A CB  1 
ATOM   1080  C CG  . TYR A 1 141 ? -57.300 1.506   -7.356   1.00 74.28  ? 141 TYR A CG  1 
ATOM   1081  C CD1 . TYR A 1 141 ? -57.173 1.173   -8.698   1.00 80.54  ? 141 TYR A CD1 1 
ATOM   1082  C CD2 . TYR A 1 141 ? -57.498 0.482   -6.441   1.00 80.39  ? 141 TYR A CD2 1 
ATOM   1083  C CE1 . TYR A 1 141 ? -57.236 -0.139  -9.118   1.00 87.42  ? 141 TYR A CE1 1 
ATOM   1084  C CE2 . TYR A 1 141 ? -57.562 -0.838  -6.852   1.00 78.11  ? 141 TYR A CE2 1 
ATOM   1085  C CZ  . TYR A 1 141 ? -57.433 -1.140  -8.193   1.00 91.04  ? 141 TYR A CZ  1 
ATOM   1086  O OH  . TYR A 1 141 ? -57.491 -2.449  -8.613   1.00 97.33  ? 141 TYR A OH  1 
ATOM   1087  N N   . GLN A 1 142 ? -60.567 3.134   -8.068   1.00 79.64  ? 142 GLN A N   1 
ATOM   1088  C CA  . GLN A 1 142 ? -61.949 2.767   -7.762   1.00 81.17  ? 142 GLN A CA  1 
ATOM   1089  C C   . GLN A 1 142 ? -62.628 3.841   -6.915   1.00 72.25  ? 142 GLN A C   1 
ATOM   1090  O O   . GLN A 1 142 ? -63.229 3.568   -5.874   1.00 75.67  ? 142 GLN A O   1 
ATOM   1091  C CB  . GLN A 1 142 ? -62.009 1.397   -7.085   1.00 72.78  ? 142 GLN A CB  1 
ATOM   1092  C CG  . GLN A 1 142 ? -61.711 0.248   -8.037   1.00 77.83  ? 142 GLN A CG  1 
ATOM   1093  C CD  . GLN A 1 142 ? -61.322 -1.029  -7.321   1.00 81.14  ? 142 GLN A CD  1 
ATOM   1094  O OE1 . GLN A 1 142 ? -61.140 -1.042  -6.104   1.00 81.06  ? 142 GLN A OE1 1 
ATOM   1095  N NE2 . GLN A 1 142 ? -61.185 -2.112  -8.077   1.00 84.48  ? 142 GLN A NE2 1 
ATOM   1096  N N   . GLY A 1 143 ? -62.519 5.082   -7.378   1.00 74.05  ? 143 GLY A N   1 
ATOM   1097  C CA  . GLY A 1 143 ? -63.156 6.208   -6.719   1.00 65.25  ? 143 GLY A CA  1 
ATOM   1098  C C   . GLY A 1 143 ? -62.625 6.521   -5.337   1.00 81.33  ? 143 GLY A C   1 
ATOM   1099  O O   . GLY A 1 143 ? -63.407 6.865   -4.442   1.00 85.74  ? 143 GLY A O   1 
ATOM   1100  N N   . ALA A 1 144 ? -61.309 6.417   -5.139   1.00 82.46  ? 144 ALA A N   1 
ATOM   1101  C CA  . ALA A 1 144 ? -60.729 6.707   -3.837   1.00 84.37  ? 144 ALA A CA  1 
ATOM   1102  C C   . ALA A 1 144 ? -59.269 7.083   -4.013   1.00 80.20  ? 144 ALA A C   1 
ATOM   1103  O O   . ALA A 1 144 ? -58.608 6.533   -4.905   1.00 79.64  ? 144 ALA A O   1 
ATOM   1104  C CB  . ALA A 1 144 ? -60.854 5.507   -2.891   1.00 64.79  ? 144 ALA A CB  1 
ATOM   1105  N N   . PRO A 1 145 ? -58.740 8.007   -3.212   1.00 78.00  ? 145 PRO A N   1 
ATOM   1106  C CA  . PRO A 1 145 ? -57.304 8.301   -3.277   1.00 68.68  ? 145 PRO A CA  1 
ATOM   1107  C C   . PRO A 1 145 ? -56.471 7.069   -2.950   1.00 76.40  ? 145 PRO A C   1 
ATOM   1108  O O   . PRO A 1 145 ? -56.822 6.267   -2.081   1.00 75.09  ? 145 PRO A O   1 
ATOM   1109  C CB  . PRO A 1 145 ? -57.122 9.403   -2.227   1.00 62.43  ? 145 PRO A CB  1 
ATOM   1110  C CG  . PRO A 1 145 ? -58.466 10.043  -2.121   1.00 65.01  ? 145 PRO A CG  1 
ATOM   1111  C CD  . PRO A 1 145 ? -59.454 8.930   -2.314   1.00 76.50  ? 145 PRO A CD  1 
ATOM   1112  N N   . SER A 1 146 ? -55.356 6.929   -3.656   1.00 75.84  ? 146 SER A N   1 
ATOM   1113  C CA  . SER A 1 146 ? -54.478 5.774   -3.515   1.00 60.41  ? 146 SER A CA  1 
ATOM   1114  C C   . SER A 1 146 ? -53.050 6.237   -3.787   1.00 69.37  ? 146 SER A C   1 
ATOM   1115  O O   . SER A 1 146 ? -52.755 7.437   -3.741   1.00 65.02  ? 146 SER A O   1 
ATOM   1116  C CB  . SER A 1 146 ? -54.938 4.637   -4.444   1.00 56.16  ? 146 SER A CB  1 
ATOM   1117  O OG  . SER A 1 146 ? -54.195 3.453   -4.211   1.00 67.35  ? 146 SER A OG  1 
ATOM   1118  N N   . PHE A 1 147 ? -52.157 5.289   -4.060   1.00 58.08  ? 147 PHE A N   1 
ATOM   1119  C CA  . PHE A 1 147 ? -50.747 5.602   -4.242   1.00 66.02  ? 147 PHE A CA  1 
ATOM   1120  C C   . PHE A 1 147 ? -50.090 4.457   -5.000   1.00 60.61  ? 147 PHE A C   1 
ATOM   1121  O O   . PHE A 1 147 ? -50.696 3.406   -5.218   1.00 64.73  ? 147 PHE A O   1 
ATOM   1122  C CB  . PHE A 1 147 ? -50.063 5.841   -2.892   1.00 67.69  ? 147 PHE A CB  1 
ATOM   1123  C CG  . PHE A 1 147 ? -48.722 6.502   -2.997   1.00 59.29  ? 147 PHE A CG  1 
ATOM   1124  C CD1 . PHE A 1 147 ? -48.610 7.792   -3.485   1.00 53.81  ? 147 PHE A CD1 1 
ATOM   1125  C CD2 . PHE A 1 147 ? -47.575 5.840   -2.591   1.00 63.22  ? 147 PHE A CD2 1 
ATOM   1126  C CE1 . PHE A 1 147 ? -47.380 8.404   -3.578   1.00 48.32  ? 147 PHE A CE1 1 
ATOM   1127  C CE2 . PHE A 1 147 ? -46.340 6.450   -2.678   1.00 60.35  ? 147 PHE A CE2 1 
ATOM   1128  C CZ  . PHE A 1 147 ? -46.243 7.734   -3.173   1.00 57.20  ? 147 PHE A CZ  1 
ATOM   1129  N N   . PHE A 1 148 ? -48.839 4.681   -5.406   1.00 62.03  ? 148 PHE A N   1 
ATOM   1130  C CA  . PHE A 1 148 ? -48.053 3.626   -6.033   1.00 52.98  ? 148 PHE A CA  1 
ATOM   1131  C C   . PHE A 1 148 ? -48.002 2.408   -5.119   1.00 61.08  ? 148 PHE A C   1 
ATOM   1132  O O   . PHE A 1 148 ? -47.813 2.527   -3.907   1.00 54.69  ? 148 PHE A O   1 
ATOM   1133  C CB  . PHE A 1 148 ? -46.629 4.109   -6.330   1.00 52.50  ? 148 PHE A CB  1 
ATOM   1134  C CG  . PHE A 1 148 ? -46.559 5.327   -7.209   1.00 49.96  ? 148 PHE A CG  1 
ATOM   1135  C CD1 . PHE A 1 148 ? -46.747 5.224   -8.578   1.00 55.97  ? 148 PHE A CD1 1 
ATOM   1136  C CD2 . PHE A 1 148 ? -46.278 6.571   -6.669   1.00 54.42  ? 148 PHE A CD2 1 
ATOM   1137  C CE1 . PHE A 1 148 ? -46.673 6.343   -9.392   1.00 50.70  ? 148 PHE A CE1 1 
ATOM   1138  C CE2 . PHE A 1 148 ? -46.200 7.694   -7.476   1.00 57.81  ? 148 PHE A CE2 1 
ATOM   1139  C CZ  . PHE A 1 148 ? -46.398 7.580   -8.839   1.00 51.56  ? 148 PHE A CZ  1 
ATOM   1140  N N   . ARG A 1 149 ? -48.183 1.229   -5.712   1.00 55.64  ? 149 ARG A N   1 
ATOM   1141  C CA  . ARG A 1 149 ? -48.310 0.012   -4.920   1.00 56.84  ? 149 ARG A CA  1 
ATOM   1142  C C   . ARG A 1 149 ? -46.973 -0.505  -4.406   1.00 61.67  ? 149 ARG A C   1 
ATOM   1143  O O   . ARG A 1 149 ? -46.933 -1.152  -3.354   1.00 74.31  ? 149 ARG A O   1 
ATOM   1144  C CB  . ARG A 1 149 ? -49.006 -1.069  -5.744   1.00 49.46  ? 149 ARG A CB  1 
ATOM   1145  C CG  . ARG A 1 149 ? -50.471 -0.779  -5.993   1.00 54.82  ? 149 ARG A CG  1 
ATOM   1146  C CD  . ARG A 1 149 ? -51.031 -1.673  -7.074   1.00 73.96  ? 149 ARG A CD  1 
ATOM   1147  N NE  . ARG A 1 149 ? -52.488 -1.663  -7.074   1.00 92.96  ? 149 ARG A NE  1 
ATOM   1148  C CZ  . ARG A 1 149 ? -53.237 -1.961  -8.125   1.00 95.54  ? 149 ARG A CZ  1 
ATOM   1149  N NH1 . ARG A 1 149 ? -52.698 -2.255  -9.297   1.00 82.49  ? 149 ARG A NH1 1 
ATOM   1150  N NH2 . ARG A 1 149 ? -54.560 -1.957  -8.000   1.00 96.88  ? 149 ARG A NH2 1 
ATOM   1151  N N   . ASN A 1 150 ? -45.879 -0.247  -5.118   1.00 58.24  ? 150 ASN A N   1 
ATOM   1152  C CA  . ASN A 1 150 ? -44.595 -0.852  -4.787   1.00 56.15  ? 150 ASN A CA  1 
ATOM   1153  C C   . ASN A 1 150 ? -43.753 -0.013  -3.831   1.00 59.26  ? 150 ASN A C   1 
ATOM   1154  O O   . ASN A 1 150 ? -42.674 -0.461  -3.426   1.00 47.49  ? 150 ASN A O   1 
ATOM   1155  C CB  . ASN A 1 150 ? -43.810 -1.137  -6.069   1.00 55.10  ? 150 ASN A CB  1 
ATOM   1156  C CG  . ASN A 1 150 ? -44.529 -2.117  -6.975   1.00 62.08  ? 150 ASN A CG  1 
ATOM   1157  O OD1 . ASN A 1 150 ? -45.273 -2.976  -6.506   1.00 58.75  ? 150 ASN A OD1 1 
ATOM   1158  N ND2 . ASN A 1 150 ? -44.318 -1.986  -8.280   1.00 64.12  ? 150 ASN A ND2 1 
ATOM   1159  N N   . VAL A 1 151 ? -44.216 1.179   -3.453   1.00 52.44  ? 151 VAL A N   1 
ATOM   1160  C CA  . VAL A 1 151 ? -43.544 2.009   -2.463   1.00 50.71  ? 151 VAL A CA  1 
ATOM   1161  C C   . VAL A 1 151 ? -44.581 2.502   -1.463   1.00 57.70  ? 151 VAL A C   1 
ATOM   1162  O O   . VAL A 1 151 ? -45.775 2.581   -1.758   1.00 50.85  ? 151 VAL A O   1 
ATOM   1163  C CB  . VAL A 1 151 ? -42.797 3.199   -3.103   1.00 54.38  ? 151 VAL A CB  1 
ATOM   1164  C CG1 . VAL A 1 151 ? -41.568 2.714   -3.851   1.00 51.41  ? 151 VAL A CG1 1 
ATOM   1165  C CG2 . VAL A 1 151 ? -43.722 3.962   -4.035   1.00 46.64  ? 151 VAL A CG2 1 
ATOM   1166  N N   . VAL A 1 152 ? -44.109 2.838   -0.264   1.00 56.24  ? 152 VAL A N   1 
ATOM   1167  C CA  . VAL A 1 152 ? -44.979 3.252   0.830    1.00 55.56  ? 152 VAL A CA  1 
ATOM   1168  C C   . VAL A 1 152 ? -44.620 4.676   1.237    1.00 52.54  ? 152 VAL A C   1 
ATOM   1169  O O   . VAL A 1 152 ? -43.450 4.984   1.496    1.00 60.78  ? 152 VAL A O   1 
ATOM   1170  C CB  . VAL A 1 152 ? -44.896 2.285   2.029    1.00 63.74  ? 152 VAL A CB  1 
ATOM   1171  C CG1 . VAL A 1 152 ? -43.457 2.092   2.489    1.00 65.64  ? 152 VAL A CG1 1 
ATOM   1172  C CG2 . VAL A 1 152 ? -45.775 2.776   3.173    1.00 63.31  ? 152 VAL A CG2 1 
ATOM   1173  N N   . TRP A 1 153 ? -45.629 5.540   1.279    1.00 58.38  ? 153 TRP A N   1 
ATOM   1174  C CA  . TRP A 1 153 ? -45.465 6.944   1.646    1.00 53.18  ? 153 TRP A CA  1 
ATOM   1175  C C   . TRP A 1 153 ? -45.619 7.053   3.159    1.00 59.76  ? 153 TRP A C   1 
ATOM   1176  O O   . TRP A 1 153 ? -46.736 7.086   3.681    1.00 58.30  ? 153 TRP A O   1 
ATOM   1177  C CB  . TRP A 1 153 ? -46.488 7.794   0.900    1.00 41.84  ? 153 TRP A CB  1 
ATOM   1178  C CG  . TRP A 1 153 ? -46.382 9.272   1.103    1.00 46.60  ? 153 TRP A CG  1 
ATOM   1179  C CD1 . TRP A 1 153 ? -45.486 9.940   1.886    1.00 47.70  ? 153 TRP A CD1 1 
ATOM   1180  C CD2 . TRP A 1 153 ? -47.214 10.271  0.503    1.00 39.08  ? 153 TRP A CD2 1 
ATOM   1181  N NE1 . TRP A 1 153 ? -45.710 11.295  1.811    1.00 49.13  ? 153 TRP A NE1 1 
ATOM   1182  C CE2 . TRP A 1 153 ? -46.767 11.522  0.968    1.00 40.52  ? 153 TRP A CE2 1 
ATOM   1183  C CE3 . TRP A 1 153 ? -48.297 10.226  -0.380   1.00 41.71  ? 153 TRP A CE3 1 
ATOM   1184  C CZ2 . TRP A 1 153 ? -47.362 12.719  0.576    1.00 43.49  ? 153 TRP A CZ2 1 
ATOM   1185  C CZ3 . TRP A 1 153 ? -48.887 11.414  -0.767   1.00 44.64  ? 153 TRP A CZ3 1 
ATOM   1186  C CH2 . TRP A 1 153 ? -48.418 12.645  -0.289   1.00 53.24  ? 153 TRP A CH2 1 
ATOM   1187  N N   . LEU A 1 154 ? -44.494 7.104   3.867    1.00 59.42  ? 154 LEU A N   1 
ATOM   1188  C CA  . LEU A 1 154 ? -44.515 7.131   5.322    1.00 57.39  ? 154 LEU A CA  1 
ATOM   1189  C C   . LEU A 1 154 ? -44.915 8.508   5.837    1.00 62.73  ? 154 LEU A C   1 
ATOM   1190  O O   . LEU A 1 154 ? -44.543 9.537   5.264    1.00 65.62  ? 154 LEU A O   1 
ATOM   1191  C CB  . LEU A 1 154 ? -43.150 6.730   5.880    1.00 54.84  ? 154 LEU A CB  1 
ATOM   1192  C CG  . LEU A 1 154 ? -42.681 5.324   5.495    1.00 63.88  ? 154 LEU A CG  1 
ATOM   1193  C CD1 . LEU A 1 154 ? -41.264 5.076   5.973    1.00 63.51  ? 154 LEU A CD1 1 
ATOM   1194  C CD2 . LEU A 1 154 ? -43.623 4.265   6.050    1.00 56.82  ? 154 LEU A CD2 1 
ATOM   1195  N N   . ILE A 1 155 ? -45.684 8.518   6.925    1.00 71.02  ? 155 ILE A N   1 
ATOM   1196  C CA  . ILE A 1 155 ? -46.210 9.733   7.534    1.00 54.28  ? 155 ILE A CA  1 
ATOM   1197  C C   . ILE A 1 155 ? -45.968 9.653   9.037    1.00 63.41  ? 155 ILE A C   1 
ATOM   1198  O O   . ILE A 1 155 ? -45.832 8.563   9.604    1.00 67.91  ? 155 ILE A O   1 
ATOM   1199  C CB  . ILE A 1 155 ? -47.714 9.918   7.195    1.00 70.70  ? 155 ILE A CB  1 
ATOM   1200  C CG1 . ILE A 1 155 ? -47.887 10.243  5.710    1.00 69.27  ? 155 ILE A CG1 1 
ATOM   1201  C CG2 . ILE A 1 155 ? -48.374 11.013  8.027    1.00 65.72  ? 155 ILE A CG2 1 
ATOM   1202  C CD1 . ILE A 1 155 ? -47.255 11.561  5.299    1.00 55.03  ? 155 ILE A CD1 1 
ATOM   1203  N N   . LYS A 1 156 ? -45.888 10.818  9.679    1.00 62.57  ? 156 LYS A N   1 
ATOM   1204  C CA  . LYS A 1 156 ? -45.700 10.875  11.122   1.00 69.16  ? 156 LYS A CA  1 
ATOM   1205  C C   . LYS A 1 156 ? -46.839 10.165  11.848   1.00 80.53  ? 156 LYS A C   1 
ATOM   1206  O O   . LYS A 1 156 ? -47.972 10.095  11.361   1.00 82.66  ? 156 LYS A O   1 
ATOM   1207  C CB  . LYS A 1 156 ? -45.616 12.329  11.592   1.00 64.84  ? 156 LYS A CB  1 
ATOM   1208  C CG  . LYS A 1 156 ? -46.957 13.060  11.589   1.00 60.51  ? 156 LYS A CG  1 
ATOM   1209  C CD  . LYS A 1 156 ? -46.828 14.479  12.123   1.00 59.94  ? 156 LYS A CD  1 
ATOM   1210  C CE  . LYS A 1 156 ? -48.193 15.119  12.314   1.00 67.53  ? 156 LYS A CE  1 
ATOM   1211  N NZ  . LYS A 1 156 ? -48.090 16.565  12.659   1.00 64.79  ? 156 LYS A NZ  1 
ATOM   1212  N N   . LYS A 1 157 ? -46.522 9.617   13.019   1.00 77.18  ? 157 LYS A N   1 
ATOM   1213  C CA  . LYS A 1 157 ? -47.508 8.982   13.883   1.00 74.73  ? 157 LYS A CA  1 
ATOM   1214  C C   . LYS A 1 157 ? -47.403 9.589   15.273   1.00 66.59  ? 157 LYS A C   1 
ATOM   1215  O O   . LYS A 1 157 ? -46.304 9.678   15.831   1.00 79.30  ? 157 LYS A O   1 
ATOM   1216  C CB  . LYS A 1 157 ? -47.306 7.462   13.945   1.00 69.40  ? 157 LYS A CB  1 
ATOM   1217  C CG  . LYS A 1 157 ? -48.341 6.738   14.798   1.00 77.30  ? 157 LYS A CG  1 
ATOM   1218  C CD  . LYS A 1 157 ? -48.768 5.419   14.166   1.00 71.24  ? 157 LYS A CD  1 
ATOM   1219  C CE  . LYS A 1 157 ? -47.726 4.329   14.359   1.00 81.19  ? 157 LYS A CE  1 
ATOM   1220  N NZ  . LYS A 1 157 ? -47.707 3.816   15.758   1.00 77.50  ? 157 LYS A NZ  1 
ATOM   1221  N N   . ASN A 1 158 ? -48.548 9.996   15.827   1.00 80.60  ? 158 ASN A N   1 
ATOM   1222  C CA  . ASN A 1 158 ? -48.610 10.644  17.139   1.00 71.36  ? 158 ASN A CA  1 
ATOM   1223  C C   . ASN A 1 158 ? -47.741 11.899  17.183   1.00 72.05  ? 158 ASN A C   1 
ATOM   1224  O O   . ASN A 1 158 ? -47.012 12.139  18.148   1.00 67.87  ? 158 ASN A O   1 
ATOM   1225  C CB  . ASN A 1 158 ? -48.221 9.672   18.255   1.00 63.04  ? 158 ASN A CB  1 
ATOM   1226  C CG  . ASN A 1 158 ? -49.179 8.502   18.366   1.00 72.74  ? 158 ASN A CG  1 
ATOM   1227  O OD1 . ASN A 1 158 ? -50.396 8.673   18.291   1.00 83.04  ? 158 ASN A OD1 1 
ATOM   1228  N ND2 . ASN A 1 158 ? -48.632 7.304   18.539   1.00 61.94  ? 158 ASN A ND2 1 
ATOM   1229  N N   . ASP A 1 159 ? -47.818 12.703  16.118   1.00 81.99  ? 159 ASP A N   1 
ATOM   1230  C CA  . ASP A 1 159 ? -47.078 13.962  16.008   1.00 71.85  ? 159 ASP A CA  1 
ATOM   1231  C C   . ASP A 1 159 ? -45.578 13.743  16.195   1.00 69.74  ? 159 ASP A C   1 
ATOM   1232  O O   . ASP A 1 159 ? -44.877 14.567  16.787   1.00 80.80  ? 159 ASP A O   1 
ATOM   1233  C CB  . ASP A 1 159 ? -47.605 15.002  17.000   1.00 73.37  ? 159 ASP A CB  1 
ATOM   1234  C CG  . ASP A 1 159 ? -47.289 16.424  16.576   1.00 92.03  ? 159 ASP A CG  1 
ATOM   1235  O OD1 . ASP A 1 159 ? -46.990 16.632  15.381   1.00 90.98  ? 159 ASP A OD1 1 
ATOM   1236  O OD2 . ASP A 1 159 ? -47.334 17.331  17.435   1.00 88.45  ? 159 ASP A OD2 1 
ATOM   1237  N N   . ALA A 1 160 ? -45.081 12.619  15.687   1.00 66.77  ? 160 ALA A N   1 
ATOM   1238  C CA  . ALA A 1 160 ? -43.670 12.287  15.808   1.00 70.55  ? 160 ALA A CA  1 
ATOM   1239  C C   . ALA A 1 160 ? -43.235 11.498  14.584   1.00 64.82  ? 160 ALA A C   1 
ATOM   1240  O O   . ALA A 1 160 ? -43.968 10.630  14.102   1.00 61.04  ? 160 ALA A O   1 
ATOM   1241  C CB  . ALA A 1 160 ? -43.390 11.483  17.083   1.00 73.12  ? 160 ALA A CB  1 
ATOM   1242  N N   . TYR A 1 161 ? -42.041 11.811  14.084   1.00 72.43  ? 161 TYR A N   1 
ATOM   1243  C CA  . TYR A 1 161 ? -41.420 11.077  12.984   1.00 63.19  ? 161 TYR A CA  1 
ATOM   1244  C C   . TYR A 1 161 ? -40.027 10.680  13.448   1.00 58.97  ? 161 TYR A C   1 
ATOM   1245  O O   . TYR A 1 161 ? -39.050 11.404  13.209   1.00 68.95  ? 161 TYR A O   1 
ATOM   1246  C CB  . TYR A 1 161 ? -41.371 11.911  11.706   1.00 63.30  ? 161 TYR A CB  1 
ATOM   1247  C CG  . TYR A 1 161 ? -41.062 11.130  10.443   1.00 63.98  ? 161 TYR A CG  1 
ATOM   1248  C CD1 . TYR A 1 161 ? -39.802 10.585  10.228   1.00 52.92  ? 161 TYR A CD1 1 
ATOM   1249  C CD2 . TYR A 1 161 ? -42.025 10.957  9.457    1.00 62.25  ? 161 TYR A CD2 1 
ATOM   1250  C CE1 . TYR A 1 161 ? -39.513 9.878   9.074    1.00 55.17  ? 161 TYR A CE1 1 
ATOM   1251  C CE2 . TYR A 1 161 ? -41.744 10.253  8.297    1.00 56.16  ? 161 TYR A CE2 1 
ATOM   1252  C CZ  . TYR A 1 161 ? -40.485 9.717   8.112    1.00 59.09  ? 161 TYR A CZ  1 
ATOM   1253  O OH  . TYR A 1 161 ? -40.195 9.017   6.963    1.00 59.29  ? 161 TYR A OH  1 
ATOM   1254  N N   . PRO A 1 162 ? -39.899 9.543   14.131   1.00 76.00  ? 162 PRO A N   1 
ATOM   1255  C CA  . PRO A 1 162 ? -38.574 9.091   14.566   1.00 64.65  ? 162 PRO A CA  1 
ATOM   1256  C C   . PRO A 1 162 ? -37.662 8.849   13.375   1.00 66.85  ? 162 PRO A C   1 
ATOM   1257  O O   . PRO A 1 162 ? -38.113 8.532   12.272   1.00 59.98  ? 162 PRO A O   1 
ATOM   1258  C CB  . PRO A 1 162 ? -38.870 7.787   15.317   1.00 70.68  ? 162 PRO A CB  1 
ATOM   1259  C CG  . PRO A 1 162 ? -40.309 7.894   15.714   1.00 68.58  ? 162 PRO A CG  1 
ATOM   1260  C CD  . PRO A 1 162 ? -40.974 8.660   14.613   1.00 73.56  ? 162 PRO A CD  1 
ATOM   1261  N N   . THR A 1 163 ? -36.363 9.028   13.603   1.00 61.36  ? 163 THR A N   1 
ATOM   1262  C CA  . THR A 1 163 ? -35.392 8.829   12.538   1.00 57.37  ? 163 THR A CA  1 
ATOM   1263  C C   . THR A 1 163 ? -35.379 7.370   12.105   1.00 63.90  ? 163 THR A C   1 
ATOM   1264  O O   . THR A 1 163 ? -35.247 6.461   12.930   1.00 70.43  ? 163 THR A O   1 
ATOM   1265  C CB  . THR A 1 163 ? -33.999 9.256   12.998   1.00 64.37  ? 163 THR A CB  1 
ATOM   1266  O OG1 . THR A 1 163 ? -34.014 10.649  13.335   1.00 57.30  ? 163 THR A OG1 1 
ATOM   1267  C CG2 . THR A 1 163 ? -32.980 9.020   11.892   1.00 56.93  ? 163 THR A CG2 1 
ATOM   1268  N N   . ILE A 1 164 ? -35.521 7.151   10.803   1.00 65.44  ? 164 ILE A N   1 
ATOM   1269  C CA  . ILE A 1 164 ? -35.520 5.806   10.243   1.00 54.68  ? 164 ILE A CA  1 
ATOM   1270  C C   . ILE A 1 164 ? -34.081 5.359   10.034   1.00 62.71  ? 164 ILE A C   1 
ATOM   1271  O O   . ILE A 1 164 ? -33.257 6.110   9.501    1.00 58.42  ? 164 ILE A O   1 
ATOM   1272  C CB  . ILE A 1 164 ? -36.312 5.770   8.928    1.00 60.54  ? 164 ILE A CB  1 
ATOM   1273  C CG1 . ILE A 1 164 ? -37.806 5.929   9.210    1.00 61.97  ? 164 ILE A CG1 1 
ATOM   1274  C CG2 . ILE A 1 164 ? -36.025 4.489   8.162    1.00 50.47  ? 164 ILE A CG2 1 
ATOM   1275  C CD1 . ILE A 1 164 ? -38.607 6.349   8.006    1.00 64.77  ? 164 ILE A CD1 1 
ATOM   1276  N N   . LYS A 1 165 ? -33.768 4.140   10.478   1.00 55.51  ? 165 LYS A N   1 
ATOM   1277  C CA  . LYS A 1 165 ? -32.459 3.519   10.251   1.00 46.12  ? 165 LYS A CA  1 
ATOM   1278  C C   . LYS A 1 165 ? -32.722 2.045   9.950    1.00 59.91  ? 165 LYS A C   1 
ATOM   1279  O O   . LYS A 1 165 ? -32.825 1.223   10.864   1.00 70.11  ? 165 LYS A O   1 
ATOM   1280  C CB  . LYS A 1 165 ? -31.527 3.693   11.444   1.00 61.27  ? 165 LYS A CB  1 
ATOM   1281  C CG  . LYS A 1 165 ? -31.109 5.126   11.719   1.00 64.57  ? 165 LYS A CG  1 
ATOM   1282  C CD  . LYS A 1 165 ? -29.908 5.174   12.650   1.00 69.21  ? 165 LYS A CD  1 
ATOM   1283  C CE  . LYS A 1 165 ? -29.458 6.604   12.902   1.00 79.18  ? 165 LYS A CE  1 
ATOM   1284  N NZ  . LYS A 1 165 ? -28.195 6.654   13.691   1.00 79.36  ? 165 LYS A NZ  1 
ATOM   1285  N N   . ILE A 1 166 ? -32.830 1.717   8.667    1.00 58.73  ? 166 ILE A N   1 
ATOM   1286  C CA  . ILE A 1 166 ? -33.162 0.367   8.234    1.00 54.96  ? 166 ILE A CA  1 
ATOM   1287  C C   . ILE A 1 166 ? -32.198 -0.049  7.134    1.00 60.88  ? 166 ILE A C   1 
ATOM   1288  O O   . ILE A 1 166 ? -31.771 0.775   6.318    1.00 60.22  ? 166 ILE A O   1 
ATOM   1289  C CB  . ILE A 1 166 ? -34.630 0.265   7.764    1.00 56.09  ? 166 ILE A CB  1 
ATOM   1290  C CG1 . ILE A 1 166 ? -35.043 -1.200  7.607    1.00 63.99  ? 166 ILE A CG1 1 
ATOM   1291  C CG2 . ILE A 1 166 ? -34.851 1.038   6.468    1.00 52.05  ? 166 ILE A CG2 1 
ATOM   1292  C CD1 . ILE A 1 166 ? -36.542 -1.409  7.563    1.00 71.26  ? 166 ILE A CD1 1 
ATOM   1293  N N   . SER A 1 167 ? -31.832 -1.326  7.133    1.00 65.20  ? 167 SER A N   1 
ATOM   1294  C CA  . SER A 1 167 ? -30.937 -1.883  6.134    1.00 62.46  ? 167 SER A CA  1 
ATOM   1295  C C   . SER A 1 167 ? -31.547 -3.152  5.563    1.00 67.14  ? 167 SER A C   1 
ATOM   1296  O O   . SER A 1 167 ? -32.327 -3.840  6.229    1.00 63.26  ? 167 SER A O   1 
ATOM   1297  C CB  . SER A 1 167 ? -29.553 -2.188  6.721    1.00 57.04  ? 167 SER A CB  1 
ATOM   1298  O OG  . SER A 1 167 ? -28.956 -1.018  7.251    1.00 72.41  ? 167 SER A OG  1 
ATOM   1299  N N   . TYR A 1 168 ? -31.194 -3.449  4.316    1.00 63.50  ? 168 TYR A N   1 
ATOM   1300  C CA  . TYR A 1 168 ? -31.600 -4.691  3.678    1.00 58.42  ? 168 TYR A CA  1 
ATOM   1301  C C   . TYR A 1 168 ? -30.399 -5.299  2.973    1.00 63.05  ? 168 TYR A C   1 
ATOM   1302  O O   . TYR A 1 168 ? -29.704 -4.609  2.221    1.00 57.78  ? 168 TYR A O   1 
ATOM   1303  C CB  . TYR A 1 168 ? -32.743 -4.468  2.679    1.00 61.43  ? 168 TYR A CB  1 
ATOM   1304  C CG  . TYR A 1 168 ? -33.035 -5.690  1.844    1.00 67.19  ? 168 TYR A CG  1 
ATOM   1305  C CD1 . TYR A 1 168 ? -33.835 -6.715  2.333    1.00 60.63  ? 168 TYR A CD1 1 
ATOM   1306  C CD2 . TYR A 1 168 ? -32.496 -5.828  0.572    1.00 49.17  ? 168 TYR A CD2 1 
ATOM   1307  C CE1 . TYR A 1 168 ? -34.096 -7.840  1.574    1.00 62.79  ? 168 TYR A CE1 1 
ATOM   1308  C CE2 . TYR A 1 168 ? -32.748 -6.947  -0.190   1.00 60.61  ? 168 TYR A CE2 1 
ATOM   1309  C CZ  . TYR A 1 168 ? -33.550 -7.951  0.313    1.00 65.60  ? 168 TYR A CZ  1 
ATOM   1310  O OH  . TYR A 1 168 ? -33.804 -9.066  -0.451   1.00 73.21  ? 168 TYR A OH  1 
ATOM   1311  N N   . ASN A 1 169 ? -30.170 -6.586  3.210    1.00 64.44  ? 169 ASN A N   1 
ATOM   1312  C CA  . ASN A 1 169 ? -29.073 -7.329  2.604    1.00 49.78  ? 169 ASN A CA  1 
ATOM   1313  C C   . ASN A 1 169 ? -29.633 -8.192  1.479    1.00 60.95  ? 169 ASN A C   1 
ATOM   1314  O O   . ASN A 1 169 ? -30.648 -8.873  1.659    1.00 58.70  ? 169 ASN A O   1 
ATOM   1315  C CB  . ASN A 1 169 ? -28.370 -8.187  3.663    1.00 52.89  ? 169 ASN A CB  1 
ATOM   1316  C CG  . ASN A 1 169 ? -27.079 -8.824  3.164    1.00 60.87  ? 169 ASN A CG  1 
ATOM   1317  O OD1 . ASN A 1 169 ? -26.991 -9.286  2.027    1.00 66.05  ? 169 ASN A OD1 1 
ATOM   1318  N ND2 . ASN A 1 169 ? -26.068 -8.855  4.033    1.00 66.84  ? 169 ASN A ND2 1 
ATOM   1319  N N   . ASN A 1 170 ? -28.985 -8.150  0.317    1.00 53.69  ? 170 ASN A N   1 
ATOM   1320  C CA  . ASN A 1 170 ? -29.440 -8.932  -0.831   1.00 63.94  ? 170 ASN A CA  1 
ATOM   1321  C C   . ASN A 1 170 ? -28.921 -10.357 -0.676   1.00 71.20  ? 170 ASN A C   1 
ATOM   1322  O O   . ASN A 1 170 ? -27.821 -10.698 -1.115   1.00 56.90  ? 170 ASN A O   1 
ATOM   1323  C CB  . ASN A 1 170 ? -28.977 -8.306  -2.141   1.00 56.58  ? 170 ASN A CB  1 
ATOM   1324  C CG  . ASN A 1 170 ? -29.532 -9.026  -3.358   1.00 62.92  ? 170 ASN A CG  1 
ATOM   1325  O OD1 . ASN A 1 170 ? -30.479 -9.804  -3.253   1.00 62.67  ? 170 ASN A OD1 1 
ATOM   1326  N ND2 . ASN A 1 170 ? -28.945 -8.766  -4.522   1.00 61.58  ? 170 ASN A ND2 1 
ATOM   1327  N N   . THR A 1 171 ? -29.731 -11.202 -0.037   1.00 66.74  ? 171 THR A N   1 
ATOM   1328  C CA  . THR A 1 171 ? -29.387 -12.606 0.143    1.00 68.30  ? 171 THR A CA  1 
ATOM   1329  C C   . THR A 1 171 ? -29.727 -13.457 -1.072   1.00 70.12  ? 171 THR A C   1 
ATOM   1330  O O   . THR A 1 171 ? -29.406 -14.650 -1.082   1.00 74.77  ? 171 THR A O   1 
ATOM   1331  C CB  . THR A 1 171 ? -30.096 -13.170 1.377    1.00 61.01  ? 171 THR A CB  1 
ATOM   1332  O OG1 . THR A 1 171 ? -31.511 -12.988 1.241    1.00 68.23  ? 171 THR A OG1 1 
ATOM   1333  C CG2 . THR A 1 171 ? -29.616 -12.463 2.637    1.00 56.39  ? 171 THR A CG2 1 
ATOM   1334  N N   . ASN A 1 172 ? -30.369 -12.882 -2.083   1.00 65.26  ? 172 ASN A N   1 
ATOM   1335  C CA  . ASN A 1 172 ? -30.667 -13.604 -3.307   1.00 52.17  ? 172 ASN A CA  1 
ATOM   1336  C C   . ASN A 1 172 ? -29.411 -13.726 -4.167   1.00 62.82  ? 172 ASN A C   1 
ATOM   1337  O O   . ASN A 1 172 ? -28.421 -13.016 -3.973   1.00 66.15  ? 172 ASN A O   1 
ATOM   1338  C CB  . ASN A 1 172 ? -31.777 -12.899 -4.087   1.00 59.90  ? 172 ASN A CB  1 
ATOM   1339  C CG  . ASN A 1 172 ? -32.911 -12.432 -3.193   1.00 62.83  ? 172 ASN A CG  1 
ATOM   1340  O OD1 . ASN A 1 172 ? -33.858 -13.174 -2.933   1.00 72.85  ? 172 ASN A OD1 1 
ATOM   1341  N ND2 . ASN A 1 172 ? -32.820 -11.195 -2.718   1.00 66.70  ? 172 ASN A ND2 1 
ATOM   1342  N N   . ARG A 1 173 ? -29.460 -14.649 -5.126   1.00 56.28  ? 173 ARG A N   1 
ATOM   1343  C CA  . ARG A 1 173 ? -28.337 -14.841 -6.034   1.00 64.29  ? 173 ARG A CA  1 
ATOM   1344  C C   . ARG A 1 173 ? -28.359 -13.885 -7.218   1.00 61.96  ? 173 ARG A C   1 
ATOM   1345  O O   . ARG A 1 173 ? -27.400 -13.871 -7.997   1.00 62.51  ? 173 ARG A O   1 
ATOM   1346  C CB  . ARG A 1 173 ? -28.308 -16.285 -6.543   1.00 79.89  ? 173 ARG A CB  1 
ATOM   1347  C CG  . ARG A 1 173 ? -27.585 -17.253 -5.621   1.00 80.85  ? 173 ARG A CG  1 
ATOM   1348  C CD  . ARG A 1 173 ? -27.736 -18.688 -6.100   1.00 85.83  ? 173 ARG A CD  1 
ATOM   1349  N NE  . ARG A 1 173 ? -29.128 -19.118 -6.064   1.00 104.90 ? 173 ARG A NE  1 
ATOM   1350  C CZ  . ARG A 1 173 ? -29.724 -19.632 -4.996   1.00 94.38  ? 173 ARG A CZ  1 
ATOM   1351  N NH1 . ARG A 1 173 ? -29.072 -19.808 -3.859   1.00 80.51  ? 173 ARG A NH1 1 
ATOM   1352  N NH2 . ARG A 1 173 ? -31.007 -19.975 -5.072   1.00 86.71  ? 173 ARG A NH2 1 
ATOM   1353  N N   . GLU A 1 174 ? -29.410 -13.085 -7.366   1.00 61.23  ? 174 GLU A N   1 
ATOM   1354  C CA  . GLU A 1 174 ? -29.563 -12.184 -8.497   1.00 64.92  ? 174 GLU A CA  1 
ATOM   1355  C C   . GLU A 1 174 ? -29.538 -10.730 -8.040   1.00 60.64  ? 174 GLU A C   1 
ATOM   1356  O O   . GLU A 1 174 ? -29.816 -10.412 -6.880   1.00 61.41  ? 174 GLU A O   1 
ATOM   1357  C CB  . GLU A 1 174 ? -30.868 -12.468 -9.250   1.00 65.66  ? 174 GLU A CB  1 
ATOM   1358  C CG  . GLU A 1 174 ? -30.909 -13.821 -9.939   1.00 70.77  ? 174 GLU A CG  1 
ATOM   1359  C CD  . GLU A 1 174 ? -31.820 -14.813 -9.244   1.00 93.12  ? 174 GLU A CD  1 
ATOM   1360  O OE1 . GLU A 1 174 ? -32.029 -14.678 -8.020   1.00 100.53 ? 174 GLU A OE1 1 
ATOM   1361  O OE2 . GLU A 1 174 ? -32.331 -15.727 -9.926   1.00 100.13 ? 174 GLU A OE2 1 
ATOM   1362  N N   . ASP A 1 175 ? -29.197 -9.848  -8.979   1.00 63.83  ? 175 ASP A N   1 
ATOM   1363  C CA  . ASP A 1 175 ? -29.232 -8.415  -8.719   1.00 55.86  ? 175 ASP A CA  1 
ATOM   1364  C C   . ASP A 1 175 ? -30.651 -7.970  -8.387   1.00 56.85  ? 175 ASP A C   1 
ATOM   1365  O O   . ASP A 1 175 ? -31.634 -8.539  -8.870   1.00 52.74  ? 175 ASP A O   1 
ATOM   1366  C CB  . ASP A 1 175 ? -28.728 -7.631  -9.935   1.00 53.15  ? 175 ASP A CB  1 
ATOM   1367  C CG  . ASP A 1 175 ? -27.261 -7.873  -10.230  1.00 55.42  ? 175 ASP A CG  1 
ATOM   1368  O OD1 . ASP A 1 175 ? -26.512 -8.220  -9.298   1.00 65.93  ? 175 ASP A OD1 1 
ATOM   1369  O OD2 . ASP A 1 175 ? -26.853 -7.706  -11.399  1.00 69.36  ? 175 ASP A OD2 1 
ATOM   1370  N N   . LEU A 1 176 ? -30.753 -6.939  -7.552   1.00 50.21  ? 176 LEU A N   1 
ATOM   1371  C CA  . LEU A 1 176 ? -32.035 -6.357  -7.180   1.00 40.70  ? 176 LEU A CA  1 
ATOM   1372  C C   . LEU A 1 176 ? -32.135 -4.934  -7.710   1.00 58.72  ? 176 LEU A C   1 
ATOM   1373  O O   . LEU A 1 176 ? -31.247 -4.111  -7.463   1.00 52.78  ? 176 LEU A O   1 
ATOM   1374  C CB  . LEU A 1 176 ? -32.227 -6.353  -5.664   1.00 54.53  ? 176 LEU A CB  1 
ATOM   1375  C CG  . LEU A 1 176 ? -32.532 -7.687  -4.986   1.00 57.67  ? 176 LEU A CG  1 
ATOM   1376  C CD1 . LEU A 1 176 ? -32.907 -7.442  -3.545   1.00 53.31  ? 176 LEU A CD1 1 
ATOM   1377  C CD2 . LEU A 1 176 ? -33.648 -8.410  -5.709   1.00 59.48  ? 176 LEU A CD2 1 
ATOM   1378  N N   . LEU A 1 177 ? -33.214 -4.651  -8.431   1.00 54.19  ? 177 LEU A N   1 
ATOM   1379  C CA  . LEU A 1 177 ? -33.572 -3.287  -8.796   1.00 50.35  ? 177 LEU A CA  1 
ATOM   1380  C C   . LEU A 1 177 ? -34.455 -2.715  -7.693   1.00 52.57  ? 177 LEU A C   1 
ATOM   1381  O O   . LEU A 1 177 ? -35.548 -3.232  -7.439   1.00 49.55  ? 177 LEU A O   1 
ATOM   1382  C CB  . LEU A 1 177 ? -34.292 -3.255  -10.144  1.00 40.99  ? 177 LEU A CB  1 
ATOM   1383  C CG  . LEU A 1 177 ? -34.918 -1.920  -10.555  1.00 46.52  ? 177 LEU A CG  1 
ATOM   1384  C CD1 . LEU A 1 177 ? -33.848 -0.847  -10.700  1.00 46.81  ? 177 LEU A CD1 1 
ATOM   1385  C CD2 . LEU A 1 177 ? -35.714 -2.066  -11.845  1.00 50.04  ? 177 LEU A CD2 1 
ATOM   1386  N N   . ILE A 1 178 ? -33.979 -1.661  -7.034   1.00 49.66  ? 178 ILE A N   1 
ATOM   1387  C CA  . ILE A 1 178 ? -34.660 -1.063  -5.891   1.00 44.19  ? 178 ILE A CA  1 
ATOM   1388  C C   . ILE A 1 178 ? -34.973 0.388   -6.222   1.00 51.72  ? 178 ILE A C   1 
ATOM   1389  O O   . ILE A 1 178 ? -34.113 1.110   -6.736   1.00 57.11  ? 178 ILE A O   1 
ATOM   1390  C CB  . ILE A 1 178 ? -33.810 -1.154  -4.609   1.00 41.63  ? 178 ILE A CB  1 
ATOM   1391  C CG1 . ILE A 1 178 ? -33.479 -2.611  -4.285   1.00 51.18  ? 178 ILE A CG1 1 
ATOM   1392  C CG2 . ILE A 1 178 ? -34.532 -0.502  -3.434   1.00 41.53  ? 178 ILE A CG2 1 
ATOM   1393  C CD1 . ILE A 1 178 ? -32.667 -2.780  -3.018   1.00 47.86  ? 178 ILE A CD1 1 
ATOM   1394  N N   . LEU A 1 179 ? -36.199 0.814   -5.926   1.00 51.79  ? 179 LEU A N   1 
ATOM   1395  C CA  . LEU A 1 179 ? -36.624 2.187   -6.148   1.00 48.25  ? 179 LEU A CA  1 
ATOM   1396  C C   . LEU A 1 179 ? -37.097 2.801   -4.839   1.00 53.83  ? 179 LEU A C   1 
ATOM   1397  O O   . LEU A 1 179 ? -37.710 2.124   -4.009   1.00 51.17  ? 179 LEU A O   1 
ATOM   1398  C CB  . LEU A 1 179 ? -37.743 2.271   -7.193   1.00 57.16  ? 179 LEU A CB  1 
ATOM   1399  C CG  . LEU A 1 179 ? -37.416 1.769   -8.602   1.00 62.46  ? 179 LEU A CG  1 
ATOM   1400  C CD1 . LEU A 1 179 ? -37.802 0.305   -8.758   1.00 55.13  ? 179 LEU A CD1 1 
ATOM   1401  C CD2 . LEU A 1 179 ? -38.095 2.628   -9.659   1.00 56.98  ? 179 LEU A CD2 1 
ATOM   1402  N N   . TRP A 1 180 ? -36.800 4.086   -4.661   1.00 44.06  ? 180 TRP A N   1 
ATOM   1403  C CA  . TRP A 1 180 ? -37.261 4.846   -3.509   1.00 48.40  ? 180 TRP A CA  1 
ATOM   1404  C C   . TRP A 1 180 ? -37.508 6.277   -3.963   1.00 48.46  ? 180 TRP A C   1 
ATOM   1405  O O   . TRP A 1 180 ? -37.317 6.618   -5.133   1.00 50.05  ? 180 TRP A O   1 
ATOM   1406  C CB  . TRP A 1 180 ? -36.254 4.788   -2.358   1.00 44.92  ? 180 TRP A CB  1 
ATOM   1407  C CG  . TRP A 1 180 ? -34.961 5.463   -2.678   1.00 53.46  ? 180 TRP A CG  1 
ATOM   1408  C CD1 . TRP A 1 180 ? -34.586 6.730   -2.331   1.00 45.95  ? 180 TRP A CD1 1 
ATOM   1409  C CD2 . TRP A 1 180 ? -33.870 4.911   -3.422   1.00 45.19  ? 180 TRP A CD2 1 
ATOM   1410  N NE1 . TRP A 1 180 ? -33.325 6.997   -2.809   1.00 47.79  ? 180 TRP A NE1 1 
ATOM   1411  C CE2 . TRP A 1 180 ? -32.865 5.897   -3.483   1.00 46.40  ? 180 TRP A CE2 1 
ATOM   1412  C CE3 . TRP A 1 180 ? -33.645 3.678   -4.041   1.00 41.34  ? 180 TRP A CE3 1 
ATOM   1413  C CZ2 . TRP A 1 180 ? -31.655 5.686   -4.137   1.00 42.96  ? 180 TRP A CZ2 1 
ATOM   1414  C CZ3 . TRP A 1 180 ? -32.443 3.472   -4.689   1.00 44.20  ? 180 TRP A CZ3 1 
ATOM   1415  C CH2 . TRP A 1 180 ? -31.465 4.469   -4.734   1.00 50.92  ? 180 TRP A CH2 1 
ATOM   1416  N N   . GLY A 1 181 ? -37.932 7.122   -3.028   1.00 45.67  ? 181 GLY A N   1 
ATOM   1417  C CA  . GLY A 1 181 ? -38.282 8.477   -3.405   1.00 39.45  ? 181 GLY A CA  1 
ATOM   1418  C C   . GLY A 1 181 ? -38.164 9.449   -2.256   1.00 45.80  ? 181 GLY A C   1 
ATOM   1419  O O   . GLY A 1 181 ? -37.968 9.073   -1.098   1.00 48.56  ? 181 GLY A O   1 
ATOM   1420  N N   . ILE A 1 182 ? -38.273 10.727  -2.609   1.00 54.08  ? 182 ILE A N   1 
ATOM   1421  C CA  . ILE A 1 182 ? -38.363 11.820  -1.653   1.00 52.36  ? 182 ILE A CA  1 
ATOM   1422  C C   . ILE A 1 182 ? -39.559 12.678  -2.043   1.00 52.35  ? 182 ILE A C   1 
ATOM   1423  O O   . ILE A 1 182 ? -39.837 12.864  -3.232   1.00 45.27  ? 182 ILE A O   1 
ATOM   1424  C CB  . ILE A 1 182 ? -37.065 12.658  -1.604   1.00 53.95  ? 182 ILE A CB  1 
ATOM   1425  C CG1 . ILE A 1 182 ? -37.164 13.737  -0.523   1.00 48.09  ? 182 ILE A CG1 1 
ATOM   1426  C CG2 . ILE A 1 182 ? -36.756 13.277  -2.966   1.00 56.28  ? 182 ILE A CG2 1 
ATOM   1427  C CD1 . ILE A 1 182 ? -35.869 14.479  -0.273   1.00 52.10  ? 182 ILE A CD1 1 
ATOM   1428  N N   . HIS A 1 183 ? -40.284 13.176  -1.045   1.00 53.36  ? 183 HIS A N   1 
ATOM   1429  C CA  . HIS A 1 183 ? -41.452 14.013  -1.281   1.00 42.86  ? 183 HIS A CA  1 
ATOM   1430  C C   . HIS A 1 183 ? -41.109 15.470  -1.007   1.00 48.70  ? 183 HIS A C   1 
ATOM   1431  O O   . HIS A 1 183 ? -40.620 15.807  0.076    1.00 53.16  ? 183 HIS A O   1 
ATOM   1432  C CB  . HIS A 1 183 ? -42.631 13.583  -0.407   1.00 49.93  ? 183 HIS A CB  1 
ATOM   1433  C CG  . HIS A 1 183 ? -43.772 14.551  -0.432   1.00 43.63  ? 183 HIS A CG  1 
ATOM   1434  N ND1 . HIS A 1 183 ? -44.180 15.251  0.682    1.00 51.73  ? 183 HIS A ND1 1 
ATOM   1435  C CD2 . HIS A 1 183 ? -44.570 14.959  -1.447   1.00 47.71  ? 183 HIS A CD2 1 
ATOM   1436  C CE1 . HIS A 1 183 ? -45.190 16.038  0.359    1.00 55.76  ? 183 HIS A CE1 1 
ATOM   1437  N NE2 . HIS A 1 183 ? -45.446 15.881  -0.928   1.00 46.94  ? 183 HIS A NE2 1 
ATOM   1438  N N   . HIS A 1 184 ? -41.373 16.329  -1.989   1.00 42.95  ? 184 HIS A N   1 
ATOM   1439  C CA  . HIS A 1 184 ? -41.146 17.762  -1.852   1.00 49.85  ? 184 HIS A CA  1 
ATOM   1440  C C   . HIS A 1 184 ? -42.439 18.425  -1.388   1.00 57.77  ? 184 HIS A C   1 
ATOM   1441  O O   . HIS A 1 184 ? -43.443 18.412  -2.109   1.00 51.76  ? 184 HIS A O   1 
ATOM   1442  C CB  . HIS A 1 184 ? -40.667 18.362  -3.173   1.00 50.35  ? 184 HIS A CB  1 
ATOM   1443  C CG  . HIS A 1 184 ? -39.401 17.751  -3.691   1.00 55.62  ? 184 HIS A CG  1 
ATOM   1444  N ND1 . HIS A 1 184 ? -38.178 17.945  -3.085   1.00 58.41  ? 184 HIS A ND1 1 
ATOM   1445  C CD2 . HIS A 1 184 ? -39.167 16.955  -4.761   1.00 52.48  ? 184 HIS A CD2 1 
ATOM   1446  C CE1 . HIS A 1 184 ? -37.247 17.291  -3.757   1.00 52.89  ? 184 HIS A CE1 1 
ATOM   1447  N NE2 . HIS A 1 184 ? -37.821 16.683  -4.779   1.00 50.09  ? 184 HIS A NE2 1 
ATOM   1448  N N   . SER A 1 185 ? -42.409 19.004  -0.190   1.00 58.65  ? 185 SER A N   1 
ATOM   1449  C CA  . SER A 1 185 ? -43.580 19.650  0.381    1.00 57.38  ? 185 SER A CA  1 
ATOM   1450  C C   . SER A 1 185 ? -43.899 20.945  -0.366   1.00 56.45  ? 185 SER A C   1 
ATOM   1451  O O   . SER A 1 185 ? -43.130 21.422  -1.206   1.00 60.30  ? 185 SER A O   1 
ATOM   1452  C CB  . SER A 1 185 ? -43.360 19.942  1.865    1.00 53.59  ? 185 SER A CB  1 
ATOM   1453  O OG  . SER A 1 185 ? -42.987 18.772  2.568    1.00 75.73  ? 185 SER A OG  1 
ATOM   1454  N N   . ASN A 1 186 ? -45.059 21.517  -0.043   1.00 57.56  ? 186 ASN A N   1 
ATOM   1455  C CA  . ASN A 1 186 ? -45.512 22.766  -0.643   1.00 60.73  ? 186 ASN A CA  1 
ATOM   1456  C C   . ASN A 1 186 ? -45.238 23.987  0.221    1.00 56.77  ? 186 ASN A C   1 
ATOM   1457  O O   . ASN A 1 186 ? -45.030 25.078  -0.319   1.00 66.13  ? 186 ASN A O   1 
ATOM   1458  C CB  . ASN A 1 186 ? -47.013 22.695  -0.942   1.00 58.98  ? 186 ASN A CB  1 
ATOM   1459  C CG  . ASN A 1 186 ? -47.329 21.785  -2.106   1.00 70.59  ? 186 ASN A CG  1 
ATOM   1460  O OD1 . ASN A 1 186 ? -46.662 21.829  -3.140   1.00 71.08  ? 186 ASN A OD1 1 
ATOM   1461  N ND2 . ASN A 1 186 ? -48.348 20.947  -1.945   1.00 68.54  ? 186 ASN A ND2 1 
ATOM   1462  N N   . ASN A 1 187 ? -45.237 23.833  1.542    1.00 58.74  ? 187 ASN A N   1 
ATOM   1463  C CA  . ASN A 1 187 ? -44.999 24.948  2.449    1.00 60.27  ? 187 ASN A CA  1 
ATOM   1464  C C   . ASN A 1 187 ? -44.584 24.390  3.803    1.00 68.18  ? 187 ASN A C   1 
ATOM   1465  O O   . ASN A 1 187 ? -44.615 23.179  4.036    1.00 71.79  ? 187 ASN A O   1 
ATOM   1466  C CB  . ASN A 1 187 ? -46.235 25.845  2.578    1.00 64.17  ? 187 ASN A CB  1 
ATOM   1467  C CG  . ASN A 1 187 ? -47.507 25.055  2.805    1.00 70.28  ? 187 ASN A CG  1 
ATOM   1468  O OD1 . ASN A 1 187 ? -47.715 24.481  3.875    1.00 61.98  ? 187 ASN A OD1 1 
ATOM   1469  N ND2 . ASN A 1 187 ? -48.371 25.025  1.796    1.00 64.39  ? 187 ASN A ND2 1 
ATOM   1470  N N   . ALA A 1 188 ? -44.191 25.301  4.696    1.00 60.40  ? 188 ALA A N   1 
ATOM   1471  C CA  . ALA A 1 188 ? -43.729 24.896  6.020    1.00 56.85  ? 188 ALA A CA  1 
ATOM   1472  C C   . ALA A 1 188 ? -44.835 24.207  6.812    1.00 72.07  ? 188 ALA A C   1 
ATOM   1473  O O   . ALA A 1 188 ? -44.583 23.215  7.508    1.00 65.33  ? 188 ALA A O   1 
ATOM   1474  C CB  . ALA A 1 188 ? -43.200 26.110  6.783    1.00 54.41  ? 188 ALA A CB  1 
ATOM   1475  N N   . GLU A 1 189 ? -46.063 24.725  6.727    1.00 64.32  ? 189 GLU A N   1 
ATOM   1476  C CA  . GLU A 1 189 ? -47.166 24.135  7.482    1.00 70.08  ? 189 GLU A CA  1 
ATOM   1477  C C   . GLU A 1 189 ? -47.446 22.708  7.029    1.00 63.16  ? 189 GLU A C   1 
ATOM   1478  O O   . GLU A 1 189 ? -47.678 21.820  7.858    1.00 67.70  ? 189 GLU A O   1 
ATOM   1479  C CB  . GLU A 1 189 ? -48.419 24.999  7.344    1.00 69.86  ? 189 GLU A CB  1 
ATOM   1480  C CG  . GLU A 1 189 ? -49.608 24.503  8.157    1.00 87.26  ? 189 GLU A CG  1 
ATOM   1481  C CD  . GLU A 1 189 ? -49.368 24.569  9.658    1.00 98.41  ? 189 GLU A CD  1 
ATOM   1482  O OE1 . GLU A 1 189 ? -48.510 25.365  10.098   1.00 98.87  ? 189 GLU A OE1 1 
ATOM   1483  O OE2 . GLU A 1 189 ? -50.042 23.823  10.399   1.00 89.69  ? 189 GLU A OE2 1 
ATOM   1484  N N   . GLU A 1 190 ? -47.429 22.468  5.715    1.00 70.02  ? 190 GLU A N   1 
ATOM   1485  C CA  . GLU A 1 190 ? -47.645 21.117  5.205    1.00 63.89  ? 190 GLU A CA  1 
ATOM   1486  C C   . GLU A 1 190 ? -46.518 20.181  5.628    1.00 57.38  ? 190 GLU A C   1 
ATOM   1487  O O   . GLU A 1 190 ? -46.754 19.001  5.914    1.00 62.74  ? 190 GLU A O   1 
ATOM   1488  C CB  . GLU A 1 190 ? -47.781 21.150  3.682    1.00 58.03  ? 190 GLU A CB  1 
ATOM   1489  C CG  . GLU A 1 190 ? -47.750 19.787  3.016    1.00 60.41  ? 190 GLU A CG  1 
ATOM   1490  C CD  . GLU A 1 190 ? -47.990 19.870  1.524    1.00 76.96  ? 190 GLU A CD  1 
ATOM   1491  O OE1 . GLU A 1 190 ? -49.066 20.361  1.123    1.00 80.40  ? 190 GLU A OE1 1 
ATOM   1492  O OE2 . GLU A 1 190 ? -47.097 19.458  0.752    1.00 72.88  ? 190 GLU A OE2 1 
ATOM   1493  N N   . GLN A 1 191 ? -45.284 20.691  5.675    1.00 60.59  ? 191 GLN A N   1 
ATOM   1494  C CA  . GLN A 1 191 ? -44.148 19.864  6.071    1.00 54.59  ? 191 GLN A CA  1 
ATOM   1495  C C   . GLN A 1 191 ? -44.297 19.355  7.502    1.00 67.55  ? 191 GLN A C   1 
ATOM   1496  O O   . GLN A 1 191 ? -44.063 18.172  7.773    1.00 63.27  ? 191 GLN A O   1 
ATOM   1497  C CB  . GLN A 1 191 ? -42.850 20.654  5.908    1.00 45.21  ? 191 GLN A CB  1 
ATOM   1498  C CG  . GLN A 1 191 ? -41.621 19.993  6.516    1.00 55.89  ? 191 GLN A CG  1 
ATOM   1499  C CD  . GLN A 1 191 ? -41.194 18.743  5.770    1.00 58.47  ? 191 GLN A CD  1 
ATOM   1500  O OE1 . GLN A 1 191 ? -41.534 18.554  4.601    1.00 56.93  ? 191 GLN A OE1 1 
ATOM   1501  N NE2 . GLN A 1 191 ? -40.440 17.882  6.444    1.00 48.16  ? 191 GLN A NE2 1 
ATOM   1502  N N   . THR A 1 192 ? -44.696 20.230  8.430    1.00 63.19  ? 192 THR A N   1 
ATOM   1503  C CA  . THR A 1 192 ? -44.880 19.805  9.814    1.00 67.89  ? 192 THR A CA  1 
ATOM   1504  C C   . THR A 1 192 ? -46.157 18.996  10.000   1.00 59.10  ? 192 THR A C   1 
ATOM   1505  O O   . THR A 1 192 ? -46.216 18.142  10.891   1.00 53.56  ? 192 THR A O   1 
ATOM   1506  C CB  . THR A 1 192 ? -44.889 21.014  10.750   1.00 58.06  ? 192 THR A CB  1 
ATOM   1507  O OG1 . THR A 1 192 ? -45.990 21.870  10.422   1.00 70.56  ? 192 THR A OG1 1 
ATOM   1508  C CG2 . THR A 1 192 ? -43.589 21.794  10.623   1.00 64.23  ? 192 THR A CG2 1 
ATOM   1509  N N   . ASN A 1 193 ? -47.182 19.247  9.181    1.00 58.88  ? 193 ASN A N   1 
ATOM   1510  C CA  . ASN A 1 193 ? -48.405 18.455  9.267    1.00 52.07  ? 193 ASN A CA  1 
ATOM   1511  C C   . ASN A 1 193 ? -48.167 17.003  8.878    1.00 67.77  ? 193 ASN A C   1 
ATOM   1512  O O   . ASN A 1 193 ? -48.826 16.105  9.414    1.00 59.28  ? 193 ASN A O   1 
ATOM   1513  C CB  . ASN A 1 193 ? -49.499 19.059  8.383    1.00 56.24  ? 193 ASN A CB  1 
ATOM   1514  C CG  . ASN A 1 193 ? -50.116 20.308  8.984    1.00 74.18  ? 193 ASN A CG  1 
ATOM   1515  O OD1 . ASN A 1 193 ? -49.898 20.621  10.155   1.00 70.53  ? 193 ASN A OD1 1 
ATOM   1516  N ND2 . ASN A 1 193 ? -50.902 21.023  8.185    1.00 60.91  ? 193 ASN A ND2 1 
ATOM   1517  N N   . LEU A 1 194 ? -47.245 16.751  7.948    1.00 67.62  ? 194 LEU A N   1 
ATOM   1518  C CA  . LEU A 1 194 ? -47.001 15.393  7.477    1.00 59.91  ? 194 LEU A CA  1 
ATOM   1519  C C   . LEU A 1 194 ? -45.872 14.698  8.230    1.00 52.63  ? 194 LEU A C   1 
ATOM   1520  O O   . LEU A 1 194 ? -45.967 13.497  8.508    1.00 62.52  ? 194 LEU A O   1 
ATOM   1521  C CB  . LEU A 1 194 ? -46.691 15.399  5.976    1.00 52.43  ? 194 LEU A CB  1 
ATOM   1522  C CG  . LEU A 1 194 ? -47.871 15.309  5.001    1.00 58.48  ? 194 LEU A CG  1 
ATOM   1523  C CD1 . LEU A 1 194 ? -48.755 16.545  5.071    1.00 66.25  ? 194 LEU A CD1 1 
ATOM   1524  C CD2 . LEU A 1 194 ? -47.380 15.081  3.576    1.00 63.31  ? 194 LEU A CD2 1 
ATOM   1525  N N   . TYR A 1 195 ? -44.804 15.421  8.571    1.00 56.51  ? 195 TYR A N   1 
ATOM   1526  C CA  . TYR A 1 195 ? -43.607 14.799  9.121    1.00 65.94  ? 195 TYR A CA  1 
ATOM   1527  C C   . TYR A 1 195 ? -43.151 15.377  10.454   1.00 55.04  ? 195 TYR A C   1 
ATOM   1528  O O   . TYR A 1 195 ? -42.277 14.778  11.091   1.00 60.29  ? 195 TYR A O   1 
ATOM   1529  C CB  . TYR A 1 195 ? -42.449 14.899  8.112    1.00 58.27  ? 195 TYR A CB  1 
ATOM   1530  C CG  . TYR A 1 195 ? -42.859 14.588  6.689    1.00 57.95  ? 195 TYR A CG  1 
ATOM   1531  C CD1 . TYR A 1 195 ? -43.032 13.276  6.265    1.00 46.70  ? 195 TYR A CD1 1 
ATOM   1532  C CD2 . TYR A 1 195 ? -43.080 15.608  5.771    1.00 51.68  ? 195 TYR A CD2 1 
ATOM   1533  C CE1 . TYR A 1 195 ? -43.413 12.988  4.968    1.00 46.17  ? 195 TYR A CE1 1 
ATOM   1534  C CE2 . TYR A 1 195 ? -43.460 15.329  4.470    1.00 51.12  ? 195 TYR A CE2 1 
ATOM   1535  C CZ  . TYR A 1 195 ? -43.625 14.018  4.075    1.00 53.43  ? 195 TYR A CZ  1 
ATOM   1536  O OH  . TYR A 1 195 ? -44.003 13.734  2.783    1.00 44.55  ? 195 TYR A OH  1 
ATOM   1537  N N   . LYS A 1 196 ? -43.654 16.547  10.855   1.00 63.41  ? 196 LYS A N   1 
ATOM   1538  C CA  . LYS A 1 196 ? -43.407 17.154  12.164   1.00 66.80  ? 196 LYS A CA  1 
ATOM   1539  C C   . LYS A 1 196 ? -41.971 17.658  12.294   1.00 63.85  ? 196 LYS A C   1 
ATOM   1540  O O   . LYS A 1 196 ? -41.658 18.445  13.193   1.00 85.27  ? 196 LYS A O   1 
ATOM   1541  C CB  . LYS A 1 196 ? -43.739 16.154  13.284   1.00 64.03  ? 196 LYS A CB  1 
ATOM   1542  C CG  . LYS A 1 196 ? -43.405 16.597  14.711   1.00 60.62  ? 196 LYS A CG  1 
ATOM   1543  C CD  . LYS A 1 196 ? -44.146 17.868  15.097   1.00 72.61  ? 196 LYS A CD  1 
ATOM   1544  C CE  . LYS A 1 196 ? -44.109 18.106  16.602   1.00 75.05  ? 196 LYS A CE  1 
ATOM   1545  N NZ  . LYS A 1 196 ? -42.756 18.487  17.093   1.00 84.88  ? 196 LYS A NZ  1 
ATOM   1546  N N   . ASN A 1 197 ? -41.107 17.282  11.356   1.00 72.82  ? 197 ASN A N   1 
ATOM   1547  C CA  . ASN A 1 197 ? -39.716 17.699  11.401   1.00 63.14  ? 197 ASN A CA  1 
ATOM   1548  C C   . ASN A 1 197 ? -39.497 18.773  10.353   1.00 54.13  ? 197 ASN A C   1 
ATOM   1549  O O   . ASN A 1 197 ? -39.712 18.508  9.160    1.00 59.47  ? 197 ASN A O   1 
ATOM   1550  C CB  . ASN A 1 197 ? -38.784 16.516  11.162   1.00 58.55  ? 197 ASN A CB  1 
ATOM   1551  C CG  . ASN A 1 197 ? -38.763 15.543  12.330   1.00 62.61  ? 197 ASN A CG  1 
ATOM   1552  O OD1 . ASN A 1 197 ? -38.888 15.943  13.487   1.00 69.30  ? 197 ASN A OD1 1 
ATOM   1553  N ND2 . ASN A 1 197 ? -38.607 14.259  12.030   1.00 58.29  ? 197 ASN A ND2 1 
ATOM   1554  N N   . PRO A 1 198 ? -39.105 19.990  10.739   1.00 66.87  ? 198 PRO A N   1 
ATOM   1555  C CA  . PRO A 1 198 ? -39.023 21.071  9.741    1.00 60.46  ? 198 PRO A CA  1 
ATOM   1556  C C   . PRO A 1 198 ? -37.909 20.878  8.727    1.00 54.68  ? 198 PRO A C   1 
ATOM   1557  O O   . PRO A 1 198 ? -38.117 21.136  7.535    1.00 53.78  ? 198 PRO A O   1 
ATOM   1558  C CB  . PRO A 1 198 ? -38.806 22.321  10.604   1.00 52.36  ? 198 PRO A CB  1 
ATOM   1559  C CG  . PRO A 1 198 ? -38.162 21.806  11.856   1.00 68.92  ? 198 PRO A CG  1 
ATOM   1560  C CD  . PRO A 1 198 ? -38.759 20.449  12.096   1.00 57.86  ? 198 PRO A CD  1 
ATOM   1561  N N   . ILE A 1 199 ? -36.731 20.437  9.162    1.00 53.25  ? 199 ILE A N   1 
ATOM   1562  C CA  . ILE A 1 199 ? -35.585 20.225  8.284    1.00 63.62  ? 199 ILE A CA  1 
ATOM   1563  C C   . ILE A 1 199 ? -35.291 18.733  8.251    1.00 56.28  ? 199 ILE A C   1 
ATOM   1564  O O   . ILE A 1 199 ? -34.928 18.142  9.275    1.00 69.08  ? 199 ILE A O   1 
ATOM   1565  C CB  . ILE A 1 199 ? -34.358 21.020  8.753    1.00 57.87  ? 199 ILE A CB  1 
ATOM   1566  C CG1 . ILE A 1 199 ? -34.683 22.514  8.807    1.00 64.95  ? 199 ILE A CG1 1 
ATOM   1567  C CG2 . ILE A 1 199 ? -33.174 20.756  7.837    1.00 61.21  ? 199 ILE A CG2 1 
ATOM   1568  C CD1 . ILE A 1 199 ? -35.155 23.084  7.488    1.00 61.18  ? 199 ILE A CD1 1 
ATOM   1569  N N   . THR A 1 200 ? -35.432 18.126  7.074    1.00 56.27  ? 200 THR A N   1 
ATOM   1570  C CA  . THR A 1 200 ? -35.336 16.682  6.928    1.00 61.19  ? 200 THR A CA  1 
ATOM   1571  C C   . THR A 1 200 ? -34.306 16.323  5.865    1.00 57.29  ? 200 THR A C   1 
ATOM   1572  O O   . THR A 1 200 ? -33.800 17.179  5.133    1.00 55.68  ? 200 THR A O   1 
ATOM   1573  C CB  . THR A 1 200 ? -36.695 16.063  6.574    1.00 54.87  ? 200 THR A CB  1 
ATOM   1574  O OG1 . THR A 1 200 ? -37.196 16.664  5.375    1.00 57.18  ? 200 THR A OG1 1 
ATOM   1575  C CG2 . THR A 1 200 ? -37.691 16.292  7.699    1.00 53.85  ? 200 THR A CG2 1 
ATOM   1576  N N   . TYR A 1 201 ? -34.006 15.029  5.787    1.00 56.34  ? 201 TYR A N   1 
ATOM   1577  C CA  . TYR A 1 201 ? -33.006 14.516  4.864    1.00 56.13  ? 201 TYR A CA  1 
ATOM   1578  C C   . TYR A 1 201 ? -33.318 13.061  4.550    1.00 62.57  ? 201 TYR A C   1 
ATOM   1579  O O   . TYR A 1 201 ? -34.093 12.405  5.250    1.00 62.16  ? 201 TYR A O   1 
ATOM   1580  C CB  . TYR A 1 201 ? -31.590 14.637  5.442    1.00 56.73  ? 201 TYR A CB  1 
ATOM   1581  C CG  . TYR A 1 201 ? -31.354 13.758  6.651    1.00 62.38  ? 201 TYR A CG  1 
ATOM   1582  C CD1 . TYR A 1 201 ? -31.710 14.185  7.925    1.00 60.55  ? 201 TYR A CD1 1 
ATOM   1583  C CD2 . TYR A 1 201 ? -30.778 12.500  6.520    1.00 58.28  ? 201 TYR A CD2 1 
ATOM   1584  C CE1 . TYR A 1 201 ? -31.501 13.385  9.034    1.00 60.41  ? 201 TYR A CE1 1 
ATOM   1585  C CE2 . TYR A 1 201 ? -30.565 11.692  7.624    1.00 67.94  ? 201 TYR A CE2 1 
ATOM   1586  C CZ  . TYR A 1 201 ? -30.928 12.140  8.877    1.00 59.88  ? 201 TYR A CZ  1 
ATOM   1587  O OH  . TYR A 1 201 ? -30.719 11.342  9.979    1.00 66.56  ? 201 TYR A OH  1 
ATOM   1588  N N   . ILE A 1 202 ? -32.708 12.565  3.476    1.00 53.62  ? 202 ILE A N   1 
ATOM   1589  C CA  . ILE A 1 202 ? -32.725 11.149  3.130    1.00 55.62  ? 202 ILE A CA  1 
ATOM   1590  C C   . ILE A 1 202 ? -31.305 10.738  2.773    1.00 55.44  ? 202 ILE A C   1 
ATOM   1591  O O   . ILE A 1 202 ? -30.687 11.343  1.890    1.00 57.26  ? 202 ILE A O   1 
ATOM   1592  C CB  . ILE A 1 202 ? -33.679 10.842  1.964    1.00 55.21  ? 202 ILE A CB  1 
ATOM   1593  C CG1 . ILE A 1 202 ? -35.133 11.020  2.392    1.00 49.51  ? 202 ILE A CG1 1 
ATOM   1594  C CG2 . ILE A 1 202 ? -33.453 9.428   1.448    1.00 51.71  ? 202 ILE A CG2 1 
ATOM   1595  C CD1 . ILE A 1 202 ? -36.113 10.722  1.290    1.00 58.30  ? 202 ILE A CD1 1 
ATOM   1596  N N   . SER A 1 203 ? -30.791 9.715   3.448    1.00 52.88  ? 203 SER A N   1 
ATOM   1597  C CA  . SER A 1 203 ? -29.498 9.126   3.130    1.00 47.06  ? 203 SER A CA  1 
ATOM   1598  C C   . SER A 1 203 ? -29.712 7.698   2.650    1.00 51.83  ? 203 SER A C   1 
ATOM   1599  O O   . SER A 1 203 ? -30.445 6.931   3.282    1.00 51.08  ? 203 SER A O   1 
ATOM   1600  C CB  . SER A 1 203 ? -28.564 9.138   4.343    1.00 47.20  ? 203 SER A CB  1 
ATOM   1601  O OG  . SER A 1 203 ? -28.265 10.461  4.749    1.00 73.49  ? 203 SER A OG  1 
ATOM   1602  N N   . VAL A 1 204 ? -29.095 7.354   1.522    1.00 51.48  ? 204 VAL A N   1 
ATOM   1603  C CA  . VAL A 1 204 ? -29.132 6.002   0.976    1.00 54.75  ? 204 VAL A CA  1 
ATOM   1604  C C   . VAL A 1 204 ? -27.705 5.589   0.652    1.00 55.70  ? 204 VAL A C   1 
ATOM   1605  O O   . VAL A 1 204 ? -26.997 6.302   -0.068   1.00 49.25  ? 204 VAL A O   1 
ATOM   1606  C CB  . VAL A 1 204 ? -30.021 5.906   -0.280   1.00 41.12  ? 204 VAL A CB  1 
ATOM   1607  C CG1 . VAL A 1 204 ? -30.229 4.449   -0.665   1.00 51.41  ? 204 VAL A CG1 1 
ATOM   1608  C CG2 . VAL A 1 204 ? -31.357 6.601   -0.056   1.00 45.05  ? 204 VAL A CG2 1 
ATOM   1609  N N   . GLY A 1 205 ? -27.286 4.441   1.175    1.00 54.69  ? 205 GLY A N   1 
ATOM   1610  C CA  . GLY A 1 205 ? -25.918 3.998   0.990    1.00 47.45  ? 205 GLY A CA  1 
ATOM   1611  C C   . GLY A 1 205 ? -25.765 2.522   0.676    1.00 54.33  ? 205 GLY A C   1 
ATOM   1612  O O   . GLY A 1 205 ? -26.353 1.668   1.344    1.00 44.97  ? 205 GLY A O   1 
ATOM   1613  N N   . THR A 1 206 ? -24.979 2.218   -0.353   1.00 50.02  ? 206 THR A N   1 
ATOM   1614  C CA  . THR A 1 206 ? -24.602 0.851   -0.681   1.00 50.14  ? 206 THR A CA  1 
ATOM   1615  C C   . THR A 1 206 ? -23.078 0.859   -0.788   1.00 48.16  ? 206 THR A C   1 
ATOM   1616  O O   . THR A 1 206 ? -22.376 1.786   -0.350   1.00 58.53  ? 206 THR A O   1 
ATOM   1617  C CB  . THR A 1 206 ? -25.284 0.327   -1.960   1.00 49.65  ? 206 THR A CB  1 
ATOM   1618  O OG1 . THR A 1 206 ? -24.624 0.875   -3.104   1.00 48.96  ? 206 THR A OG1 1 
ATOM   1619  C CG2 . THR A 1 206 ? -26.755 0.700   -1.979   1.00 47.50  ? 206 THR A CG2 1 
ATOM   1620  N N   . SER A 1 207 ? -22.524 -0.217  -1.350   1.00 54.18  ? 207 SER A N   1 
ATOM   1621  C CA  . SER A 1 207 ? -21.089 -0.263  -1.631   1.00 49.75  ? 207 SER A CA  1 
ATOM   1622  C C   . SER A 1 207 ? -20.679 0.772   -2.676   1.00 51.14  ? 207 SER A C   1 
ATOM   1623  O O   . SER A 1 207 ? -19.527 1.223   -2.678   1.00 57.62  ? 207 SER A O   1 
ATOM   1624  C CB  . SER A 1 207 ? -20.684 -1.668  -2.086   1.00 47.95  ? 207 SER A CB  1 
ATOM   1625  O OG  . SER A 1 207 ? -21.360 -2.020  -3.279   1.00 54.40  ? 207 SER A OG  1 
ATOM   1626  N N   . THR A 1 208 ? -21.593 1.169   -3.564   1.00 51.19  ? 208 THR A N   1 
ATOM   1627  C CA  . THR A 1 208 ? -21.300 2.174   -4.580   1.00 53.69  ? 208 THR A CA  1 
ATOM   1628  C C   . THR A 1 208 ? -22.192 3.403   -4.510   1.00 49.73  ? 208 THR A C   1 
ATOM   1629  O O   . THR A 1 208 ? -21.774 4.474   -4.955   1.00 52.74  ? 208 THR A O   1 
ATOM   1630  C CB  . THR A 1 208 ? -21.413 1.573   -5.992   1.00 47.08  ? 208 THR A CB  1 
ATOM   1631  O OG1 . THR A 1 208 ? -22.733 1.051   -6.195   1.00 55.50  ? 208 THR A OG1 1 
ATOM   1632  C CG2 . THR A 1 208 ? -20.393 0.461   -6.184   1.00 46.43  ? 208 THR A CG2 1 
ATOM   1633  N N   . LEU A 1 209 ? -23.398 3.288   -3.963   1.00 51.46  ? 209 LEU A N   1 
ATOM   1634  C CA  . LEU A 1 209 ? -24.303 4.423   -3.876   1.00 46.50  ? 209 LEU A CA  1 
ATOM   1635  C C   . LEU A 1 209 ? -24.012 5.250   -2.629   1.00 47.66  ? 209 LEU A C   1 
ATOM   1636  O O   . LEU A 1 209 ? -23.762 4.708   -1.548   1.00 49.34  ? 209 LEU A O   1 
ATOM   1637  C CB  . LEU A 1 209 ? -25.751 3.937   -3.862   1.00 50.40  ? 209 LEU A CB  1 
ATOM   1638  C CG  . LEU A 1 209 ? -26.864 4.979   -3.787   1.00 56.54  ? 209 LEU A CG  1 
ATOM   1639  C CD1 . LEU A 1 209 ? -26.862 5.875   -5.017   1.00 35.74  ? 209 LEU A CD1 1 
ATOM   1640  C CD2 . LEU A 1 209 ? -28.195 4.276   -3.636   1.00 45.29  ? 209 LEU A CD2 1 
ATOM   1641  N N   . ASN A 1 210 ? -24.034 6.575   -2.790   1.00 41.26  ? 210 ASN A N   1 
ATOM   1642  C CA  . ASN A 1 210 ? -23.806 7.503   -1.679   1.00 45.43  ? 210 ASN A CA  1 
ATOM   1643  C C   . ASN A 1 210 ? -24.641 8.754   -1.969   1.00 56.77  ? 210 ASN A C   1 
ATOM   1644  O O   . ASN A 1 210 ? -24.183 9.678   -2.645   1.00 56.62  ? 210 ASN A O   1 
ATOM   1645  C CB  . ASN A 1 210 ? -22.326 7.826   -1.526   1.00 52.18  ? 210 ASN A CB  1 
ATOM   1646  C CG  . ASN A 1 210 ? -22.029 8.663   -0.296   1.00 48.83  ? 210 ASN A CG  1 
ATOM   1647  O OD1 . ASN A 1 210 ? -22.715 8.566   0.720    1.00 53.04  ? 210 ASN A OD1 1 
ATOM   1648  N ND2 . ASN A 1 210 ? -20.996 9.492   -0.386   1.00 50.68  ? 210 ASN A ND2 1 
ATOM   1649  N N   . GLN A 1 211 ? -25.864 8.774   -1.440   1.00 46.18  ? 211 GLN A N   1 
ATOM   1650  C CA  . GLN A 1 211 ? -26.841 9.810   -1.748   1.00 54.87  ? 211 GLN A CA  1 
ATOM   1651  C C   . GLN A 1 211 ? -27.346 10.451  -0.464   1.00 46.70  ? 211 GLN A C   1 
ATOM   1652  O O   . GLN A 1 211 ? -27.662 9.749   0.499    1.00 48.85  ? 211 GLN A O   1 
ATOM   1653  C CB  . GLN A 1 211 ? -28.021 9.230   -2.538   1.00 38.03  ? 211 GLN A CB  1 
ATOM   1654  C CG  . GLN A 1 211 ? -29.174 10.207  -2.724   1.00 48.09  ? 211 GLN A CG  1 
ATOM   1655  C CD  . GLN A 1 211 ? -30.403 9.569   -3.343   1.00 59.12  ? 211 GLN A CD  1 
ATOM   1656  O OE1 . GLN A 1 211 ? -31.055 8.721   -2.731   1.00 51.14  ? 211 GLN A OE1 1 
ATOM   1657  N NE2 . GLN A 1 211 ? -30.730 9.979   -4.563   1.00 63.75  ? 211 GLN A NE2 1 
ATOM   1658  N N   . ARG A 1 212 ? -27.419 11.782  -0.454   1.00 49.75  ? 212 ARG A N   1 
ATOM   1659  C CA  . ARG A 1 212 ? -28.114 12.512  0.598    1.00 55.30  ? 212 ARG A CA  1 
ATOM   1660  C C   . ARG A 1 212 ? -28.967 13.593  -0.048   1.00 53.35  ? 212 ARG A C   1 
ATOM   1661  O O   . ARG A 1 212 ? -28.457 14.412  -0.818   1.00 56.28  ? 212 ARG A O   1 
ATOM   1662  C CB  . ARG A 1 212 ? -27.142 13.127  1.612    1.00 58.58  ? 212 ARG A CB  1 
ATOM   1663  C CG  . ARG A 1 212 ? -27.841 13.708  2.841    1.00 57.29  ? 212 ARG A CG  1 
ATOM   1664  C CD  . ARG A 1 212 ? -26.892 13.877  4.022    1.00 68.56  ? 212 ARG A CD  1 
ATOM   1665  N NE  . ARG A 1 212 ? -27.559 14.471  5.177    1.00 71.97  ? 212 ARG A NE  1 
ATOM   1666  C CZ  . ARG A 1 212 ? -27.687 13.886  6.361    1.00 82.28  ? 212 ARG A CZ  1 
ATOM   1667  N NH1 . ARG A 1 212 ? -27.173 12.691  6.602    1.00 83.42  ? 212 ARG A NH1 1 
ATOM   1668  N NH2 . ARG A 1 212 ? -28.339 14.522  7.331    1.00 83.59  ? 212 ARG A NH2 1 
ATOM   1669  N N   . LEU A 1 213 ? -30.259 13.593  0.269    1.00 56.34  ? 213 LEU A N   1 
ATOM   1670  C CA  . LEU A 1 213 ? -31.218 14.504  -0.335   1.00 55.88  ? 213 LEU A CA  1 
ATOM   1671  C C   . LEU A 1 213 ? -31.950 15.290  0.741    1.00 49.99  ? 213 LEU A C   1 
ATOM   1672  O O   . LEU A 1 213 ? -32.175 14.798  1.849    1.00 58.72  ? 213 LEU A O   1 
ATOM   1673  C CB  . LEU A 1 213 ? -32.249 13.752  -1.181   1.00 57.25  ? 213 LEU A CB  1 
ATOM   1674  C CG  . LEU A 1 213 ? -31.732 12.821  -2.275   1.00 72.63  ? 213 LEU A CG  1 
ATOM   1675  C CD1 . LEU A 1 213 ? -32.858 11.921  -2.730   1.00 61.43  ? 213 LEU A CD1 1 
ATOM   1676  C CD2 . LEU A 1 213 ? -31.175 13.620  -3.440   1.00 64.73  ? 213 LEU A CD2 1 
ATOM   1677  N N   . ALA A 1 214 ? -32.328 16.517  0.395    1.00 55.54  ? 214 ALA A N   1 
ATOM   1678  C CA  . ALA A 1 214 ? -33.180 17.342  1.230    1.00 53.88  ? 214 ALA A CA  1 
ATOM   1679  C C   . ALA A 1 214 ? -34.367 17.816  0.404    1.00 47.28  ? 214 ALA A C   1 
ATOM   1680  O O   . ALA A 1 214 ? -34.218 18.102  -0.791   1.00 58.27  ? 214 ALA A O   1 
ATOM   1681  C CB  . ALA A 1 214 ? -32.415 18.550  1.792    1.00 45.60  ? 214 ALA A CB  1 
ATOM   1682  N N   . PRO A 1 215 ? -35.552 17.900  1.002    1.00 53.01  ? 215 PRO A N   1 
ATOM   1683  C CA  . PRO A 1 215 ? -36.729 18.331  0.242    1.00 47.22  ? 215 PRO A CA  1 
ATOM   1684  C C   . PRO A 1 215 ? -36.609 19.779  -0.197   1.00 52.08  ? 215 PRO A C   1 
ATOM   1685  O O   . PRO A 1 215 ? -36.011 20.614  0.485    1.00 52.83  ? 215 PRO A O   1 
ATOM   1686  C CB  . PRO A 1 215 ? -37.884 18.154  1.237    1.00 55.98  ? 215 PRO A CB  1 
ATOM   1687  C CG  . PRO A 1 215 ? -37.336 17.313  2.340    1.00 49.51  ? 215 PRO A CG  1 
ATOM   1688  C CD  . PRO A 1 215 ? -35.877 17.599  2.404    1.00 53.29  ? 215 PRO A CD  1 
ATOM   1689  N N   . LYS A 1 216 ? -37.203 20.071  -1.350   1.00 52.89  ? 216 LYS A N   1 
ATOM   1690  C CA  . LYS A 1 216 ? -37.234 21.424  -1.901   1.00 47.09  ? 216 LYS A CA  1 
ATOM   1691  C C   . LYS A 1 216 ? -38.643 21.970  -1.689   1.00 53.98  ? 216 LYS A C   1 
ATOM   1692  O O   . LYS A 1 216 ? -39.537 21.784  -2.514   1.00 55.58  ? 216 LYS A O   1 
ATOM   1693  C CB  . LYS A 1 216 ? -36.819 21.419  -3.369   1.00 52.58  ? 216 LYS A CB  1 
ATOM   1694  C CG  . LYS A 1 216 ? -35.373 20.982  -3.577   1.00 57.05  ? 216 LYS A CG  1 
ATOM   1695  C CD  . LYS A 1 216 ? -34.942 21.065  -5.034   1.00 44.57  ? 216 LYS A CD  1 
ATOM   1696  C CE  . LYS A 1 216 ? -35.383 19.847  -5.826   1.00 56.23  ? 216 LYS A CE  1 
ATOM   1697  N NZ  . LYS A 1 216 ? -34.868 19.894  -7.227   1.00 58.69  ? 216 LYS A NZ  1 
ATOM   1698  N N   . ILE A 1 217 ? -38.836 22.645  -0.559   1.00 62.39  ? 217 ILE A N   1 
ATOM   1699  C CA  . ILE A 1 217 ? -40.134 23.197  -0.182   1.00 60.20  ? 217 ILE A CA  1 
ATOM   1700  C C   . ILE A 1 217 ? -40.331 24.503  -0.946   1.00 56.20  ? 217 ILE A C   1 
ATOM   1701  O O   . ILE A 1 217 ? -39.689 25.510  -0.642   1.00 68.55  ? 217 ILE A O   1 
ATOM   1702  C CB  . ILE A 1 217 ? -40.226 23.420  1.332    1.00 59.10  ? 217 ILE A CB  1 
ATOM   1703  C CG1 . ILE A 1 217 ? -39.944 22.117  2.083    1.00 60.87  ? 217 ILE A CG1 1 
ATOM   1704  C CG2 . ILE A 1 217 ? -41.588 23.972  1.716    1.00 55.58  ? 217 ILE A CG2 1 
ATOM   1705  C CD1 . ILE A 1 217 ? -39.953 22.265  3.592    1.00 67.10  ? 217 ILE A CD1 1 
ATOM   1706  N N   . ALA A 1 218 ? -41.219 24.490  -1.938   1.00 63.41  ? 218 ALA A N   1 
ATOM   1707  C CA  . ALA A 1 218 ? -41.406 25.655  -2.793   1.00 54.18  ? 218 ALA A CA  1 
ATOM   1708  C C   . ALA A 1 218 ? -42.775 25.594  -3.454   1.00 58.43  ? 218 ALA A C   1 
ATOM   1709  O O   . ALA A 1 218 ? -43.431 24.550  -3.481   1.00 62.65  ? 218 ALA A O   1 
ATOM   1710  C CB  . ALA A 1 218 ? -40.306 25.751  -3.855   1.00 47.30  ? 218 ALA A CB  1 
ATOM   1711  N N   . THR A 1 219 ? -43.191 26.739  -3.993   1.00 54.37  ? 219 THR A N   1 
ATOM   1712  C CA  . THR A 1 219 ? -44.461 26.845  -4.697   1.00 50.71  ? 219 THR A CA  1 
ATOM   1713  C C   . THR A 1 219 ? -44.305 26.353  -6.131   1.00 56.15  ? 219 THR A C   1 
ATOM   1714  O O   . THR A 1 219 ? -43.370 26.749  -6.833   1.00 52.38  ? 219 THR A O   1 
ATOM   1715  C CB  . THR A 1 219 ? -44.957 28.292  -4.686   1.00 55.83  ? 219 THR A CB  1 
ATOM   1716  O OG1 . THR A 1 219 ? -45.053 28.758  -3.334   1.00 58.62  ? 219 THR A OG1 1 
ATOM   1717  C CG2 . THR A 1 219 ? -46.320 28.396  -5.352   1.00 55.09  ? 219 THR A CG2 1 
ATOM   1718  N N   . ARG A 1 220 ? -45.226 25.493  -6.565   1.00 54.63  ? 220 ARG A N   1 
ATOM   1719  C CA  . ARG A 1 220 ? -45.177 24.901  -7.894   1.00 59.87  ? 220 ARG A CA  1 
ATOM   1720  C C   . ARG A 1 220 ? -46.579 24.866  -8.488   1.00 64.31  ? 220 ARG A C   1 
ATOM   1721  O O   . ARG A 1 220 ? -47.580 25.006  -7.782   1.00 63.71  ? 220 ARG A O   1 
ATOM   1722  C CB  . ARG A 1 220 ? -44.584 23.486  -7.864   1.00 52.78  ? 220 ARG A CB  1 
ATOM   1723  C CG  . ARG A 1 220 ? -43.095 23.436  -7.564   1.00 52.27  ? 220 ARG A CG  1 
ATOM   1724  C CD  . ARG A 1 220 ? -42.657 22.022  -7.235   1.00 46.95  ? 220 ARG A CD  1 
ATOM   1725  N NE  . ARG A 1 220 ? -43.285 21.543  -6.010   1.00 54.97  ? 220 ARG A NE  1 
ATOM   1726  C CZ  . ARG A 1 220 ? -42.702 21.550  -4.820   1.00 57.46  ? 220 ARG A CZ  1 
ATOM   1727  N NH1 . ARG A 1 220 ? -41.459 21.975  -4.661   1.00 54.09  ? 220 ARG A NH1 1 
ATOM   1728  N NH2 . ARG A 1 220 ? -43.384 21.119  -3.762   1.00 53.19  ? 220 ARG A NH2 1 
ATOM   1729  N N   . SER A 1 221 ? -46.636 24.681  -9.805   1.00 56.59  ? 221 SER A N   1 
ATOM   1730  C CA  . SER A 1 221 ? -47.913 24.585  -10.497  1.00 60.02  ? 221 SER A CA  1 
ATOM   1731  C C   . SER A 1 221 ? -48.587 23.248  -10.209  1.00 62.33  ? 221 SER A C   1 
ATOM   1732  O O   . SER A 1 221 ? -47.932 22.242  -9.924   1.00 57.99  ? 221 SER A O   1 
ATOM   1733  C CB  . SER A 1 221 ? -47.718 24.751  -12.005  1.00 54.35  ? 221 SER A CB  1 
ATOM   1734  O OG  . SER A 1 221 ? -47.130 26.002  -12.312  1.00 58.71  ? 221 SER A OG  1 
ATOM   1735  N N   . GLN A 1 222 ? -49.915 23.245  -10.290  1.00 65.42  ? 222 GLN A N   1 
ATOM   1736  C CA  . GLN A 1 222 ? -50.673 22.020  -10.074  1.00 62.66  ? 222 GLN A CA  1 
ATOM   1737  C C   . GLN A 1 222 ? -50.521 21.081  -11.264  1.00 57.69  ? 222 GLN A C   1 
ATOM   1738  O O   . GLN A 1 222 ? -50.716 21.481  -12.416  1.00 63.30  ? 222 GLN A O   1 
ATOM   1739  C CB  . GLN A 1 222 ? -52.150 22.340  -9.838   1.00 62.81  ? 222 GLN A CB  1 
ATOM   1740  C CG  . GLN A 1 222 ? -52.475 22.744  -8.410   1.00 84.86  ? 222 GLN A CG  1 
ATOM   1741  C CD  . GLN A 1 222 ? -53.899 23.239  -8.244   1.00 86.20  ? 222 GLN A CD  1 
ATOM   1742  O OE1 . GLN A 1 222 ? -54.682 23.246  -9.194   1.00 85.55  ? 222 GLN A OE1 1 
ATOM   1743  N NE2 . GLN A 1 222 ? -54.240 23.661  -7.032   1.00 79.35  ? 222 GLN A NE2 1 
ATOM   1744  N N   . VAL A 1 223 ? -50.161 19.831  -10.980  1.00 51.62  ? 223 VAL A N   1 
ATOM   1745  C CA  . VAL A 1 223 ? -50.125 18.761  -11.970  1.00 44.63  ? 223 VAL A CA  1 
ATOM   1746  C C   . VAL A 1 223 ? -50.903 17.590  -11.390  1.00 55.91  ? 223 VAL A C   1 
ATOM   1747  O O   . VAL A 1 223 ? -50.591 17.123  -10.288  1.00 58.28  ? 223 VAL A O   1 
ATOM   1748  C CB  . VAL A 1 223 ? -48.690 18.338  -12.324  1.00 55.56  ? 223 VAL A CB  1 
ATOM   1749  C CG1 . VAL A 1 223 ? -48.705 17.227  -13.366  1.00 48.37  ? 223 VAL A CG1 1 
ATOM   1750  C CG2 . VAL A 1 223 ? -47.887 19.531  -12.821  1.00 52.29  ? 223 VAL A CG2 1 
ATOM   1751  N N   . ASN A 1 224 ? -51.914 17.123  -12.125  1.00 56.79  ? 224 ASN A N   1 
ATOM   1752  C CA  . ASN A 1 224 ? -52.852 16.119  -11.619  1.00 57.58  ? 224 ASN A CA  1 
ATOM   1753  C C   . ASN A 1 224 ? -53.464 16.567  -10.293  1.00 64.10  ? 224 ASN A C   1 
ATOM   1754  O O   . ASN A 1 224 ? -53.722 15.761  -9.395   1.00 60.73  ? 224 ASN A O   1 
ATOM   1755  C CB  . ASN A 1 224 ? -52.183 14.749  -11.480  1.00 64.21  ? 224 ASN A CB  1 
ATOM   1756  C CG  . ASN A 1 224 ? -51.792 14.152  -12.817  1.00 65.07  ? 224 ASN A CG  1 
ATOM   1757  O OD1 . ASN A 1 224 ? -52.214 14.631  -13.869  1.00 68.60  ? 224 ASN A OD1 1 
ATOM   1758  N ND2 . ASN A 1 224 ? -50.991 13.092  -12.783  1.00 69.01  ? 224 ASN A ND2 1 
ATOM   1759  N N   . GLY A 1 225 ? -53.688 17.874  -10.167  1.00 58.23  ? 225 GLY A N   1 
ATOM   1760  C CA  . GLY A 1 225 ? -54.328 18.442  -9.000   1.00 62.97  ? 225 GLY A CA  1 
ATOM   1761  C C   . GLY A 1 225 ? -53.431 18.684  -7.806   1.00 67.66  ? 225 GLY A C   1 
ATOM   1762  O O   . GLY A 1 225 ? -53.927 19.141  -6.768   1.00 61.09  ? 225 GLY A O   1 
ATOM   1763  N N   . GLN A 1 226 ? -52.134 18.404  -7.909   1.00 65.28  ? 226 GLN A N   1 
ATOM   1764  C CA  . GLN A 1 226 ? -51.215 18.524  -6.786   1.00 60.39  ? 226 GLN A CA  1 
ATOM   1765  C C   . GLN A 1 226 ? -50.067 19.463  -7.127   1.00 59.41  ? 226 GLN A C   1 
ATOM   1766  O O   . GLN A 1 226 ? -49.543 19.438  -8.246   1.00 57.04  ? 226 GLN A O   1 
ATOM   1767  C CB  . GLN A 1 226 ? -50.661 17.155  -6.381   1.00 65.55  ? 226 GLN A CB  1 
ATOM   1768  C CG  . GLN A 1 226 ? -51.657 16.300  -5.628   1.00 58.71  ? 226 GLN A CG  1 
ATOM   1769  C CD  . GLN A 1 226 ? -52.136 16.973  -4.358   1.00 69.87  ? 226 GLN A CD  1 
ATOM   1770  O OE1 . GLN A 1 226 ? -51.347 17.564  -3.618   1.00 64.04  ? 226 GLN A OE1 1 
ATOM   1771  N NE2 . GLN A 1 226 ? -53.436 16.901  -4.106   1.00 74.18  ? 226 GLN A NE2 1 
ATOM   1772  N N   . ARG A 1 227 ? -49.683 20.292  -6.154   1.00 52.84  ? 227 ARG A N   1 
ATOM   1773  C CA  . ARG A 1 227 ? -48.515 21.152  -6.290   1.00 61.18  ? 227 ARG A CA  1 
ATOM   1774  C C   . ARG A 1 227 ? -47.239 20.502  -5.774   1.00 54.57  ? 227 ARG A C   1 
ATOM   1775  O O   . ARG A 1 227 ? -46.144 20.959  -6.119   1.00 62.61  ? 227 ARG A O   1 
ATOM   1776  C CB  . ARG A 1 227 ? -48.736 22.477  -5.552   1.00 53.77  ? 227 ARG A CB  1 
ATOM   1777  C CG  . ARG A 1 227 ? -49.953 23.246  -6.020   1.00 53.61  ? 227 ARG A CG  1 
ATOM   1778  C CD  . ARG A 1 227 ? -49.965 24.665  -5.486   1.00 51.52  ? 227 ARG A CD  1 
ATOM   1779  N NE  . ARG A 1 227 ? -51.105 25.416  -5.998   1.00 77.76  ? 227 ARG A NE  1 
ATOM   1780  C CZ  . ARG A 1 227 ? -51.131 26.029  -7.173   1.00 81.25  ? 227 ARG A CZ  1 
ATOM   1781  N NH1 . ARG A 1 227 ? -50.085 26.015  -7.984   1.00 73.29  ? 227 ARG A NH1 1 
ATOM   1782  N NH2 . ARG A 1 227 ? -52.235 26.671  -7.546   1.00 86.11  ? 227 ARG A NH2 1 
ATOM   1783  N N   . GLY A 1 228 ? -47.352 19.464  -4.954   1.00 60.44  ? 228 GLY A N   1 
ATOM   1784  C CA  . GLY A 1 228 ? -46.182 18.759  -4.479   1.00 53.01  ? 228 GLY A CA  1 
ATOM   1785  C C   . GLY A 1 228 ? -45.578 17.880  -5.557   1.00 50.94  ? 228 GLY A C   1 
ATOM   1786  O O   . GLY A 1 228 ? -46.153 17.653  -6.623   1.00 51.03  ? 228 GLY A O   1 
ATOM   1787  N N   . ARG A 1 229 ? -44.378 17.381  -5.270   1.00 46.71  ? 229 ARG A N   1 
ATOM   1788  C CA  . ARG A 1 229 ? -43.645 16.548  -6.212   1.00 57.34  ? 229 ARG A CA  1 
ATOM   1789  C C   . ARG A 1 229 ? -42.975 15.408  -5.462   1.00 49.13  ? 229 ARG A C   1 
ATOM   1790  O O   . ARG A 1 229 ? -42.721 15.491  -4.258   1.00 47.79  ? 229 ARG A O   1 
ATOM   1791  C CB  . ARG A 1 229 ? -42.583 17.346  -6.984   1.00 38.22  ? 229 ARG A CB  1 
ATOM   1792  C CG  . ARG A 1 229 ? -43.123 18.485  -7.825   1.00 36.92  ? 229 ARG A CG  1 
ATOM   1793  C CD  . ARG A 1 229 ? -43.974 17.982  -8.971   1.00 44.65  ? 229 ARG A CD  1 
ATOM   1794  N NE  . ARG A 1 229 ? -44.416 19.083  -9.818   1.00 49.25  ? 229 ARG A NE  1 
ATOM   1795  C CZ  . ARG A 1 229 ? -45.548 19.750  -9.646   1.00 54.15  ? 229 ARG A CZ  1 
ATOM   1796  N NH1 . ARG A 1 229 ? -46.398 19.434  -8.683   1.00 59.27  ? 229 ARG A NH1 1 
ATOM   1797  N NH2 . ARG A 1 229 ? -45.833 20.764  -10.459  1.00 50.60  ? 229 ARG A NH2 1 
ATOM   1798  N N   . MET A 1 230 ? -42.689 14.336  -6.197   1.00 44.05  ? 230 MET A N   1 
ATOM   1799  C CA  . MET A 1 230 ? -41.901 13.223  -5.683   1.00 49.07  ? 230 MET A CA  1 
ATOM   1800  C C   . MET A 1 230 ? -40.837 12.862  -6.705   1.00 52.10  ? 230 MET A C   1 
ATOM   1801  O O   . MET A 1 230 ? -41.156 12.595  -7.868   1.00 50.04  ? 230 MET A O   1 
ATOM   1802  C CB  . MET A 1 230 ? -42.778 12.009  -5.376   1.00 48.67  ? 230 MET A CB  1 
ATOM   1803  C CG  . MET A 1 230 ? -43.686 12.198  -4.181   1.00 52.91  ? 230 MET A CG  1 
ATOM   1804  S SD  . MET A 1 230 ? -44.663 10.729  -3.845   1.00 60.05  ? 230 MET A SD  1 
ATOM   1805  C CE  . MET A 1 230 ? -45.847 11.394  -2.678   1.00 54.26  ? 230 MET A CE  1 
ATOM   1806  N N   . ASP A 1 231 ? -39.581 12.854  -6.274   1.00 50.45  ? 231 ASP A N   1 
ATOM   1807  C CA  . ASP A 1 231 ? -38.468 12.422  -7.107   1.00 43.44  ? 231 ASP A CA  1 
ATOM   1808  C C   . ASP A 1 231 ? -38.106 10.995  -6.722   1.00 49.87  ? 231 ASP A C   1 
ATOM   1809  O O   . ASP A 1 231 ? -37.803 10.721  -5.556   1.00 46.63  ? 231 ASP A O   1 
ATOM   1810  C CB  . ASP A 1 231 ? -37.262 13.345  -6.943   1.00 51.55  ? 231 ASP A CB  1 
ATOM   1811  C CG  . ASP A 1 231 ? -37.507 14.728  -7.505   1.00 48.50  ? 231 ASP A CG  1 
ATOM   1812  O OD1 . ASP A 1 231 ? -38.311 14.850  -8.452   1.00 65.88  ? 231 ASP A OD1 1 
ATOM   1813  O OD2 . ASP A 1 231 ? -36.891 15.691  -7.004   1.00 65.91  ? 231 ASP A OD2 1 
ATOM   1814  N N   . PHE A 1 232 ? -38.143 10.094  -7.695   1.00 41.94  ? 232 PHE A N   1 
ATOM   1815  C CA  . PHE A 1 232 ? -37.817 8.697   -7.466   1.00 44.68  ? 232 PHE A CA  1 
ATOM   1816  C C   . PHE A 1 232 ? -36.440 8.383   -8.033   1.00 43.84  ? 232 PHE A C   1 
ATOM   1817  O O   . PHE A 1 232 ? -36.014 8.957   -9.038   1.00 50.79  ? 232 PHE A O   1 
ATOM   1818  C CB  . PHE A 1 232 ? -38.873 7.774   -8.083   1.00 48.50  ? 232 PHE A CB  1 
ATOM   1819  C CG  . PHE A 1 232 ? -40.167 7.750   -7.323   1.00 52.87  ? 232 PHE A CG  1 
ATOM   1820  C CD1 . PHE A 1 232 ? -40.291 6.993   -6.167   1.00 59.71  ? 232 PHE A CD1 1 
ATOM   1821  C CD2 . PHE A 1 232 ? -41.257 8.486   -7.756   1.00 52.22  ? 232 PHE A CD2 1 
ATOM   1822  C CE1 . PHE A 1 232 ? -41.478 6.969   -5.458   1.00 52.85  ? 232 PHE A CE1 1 
ATOM   1823  C CE2 . PHE A 1 232 ? -42.448 8.468   -7.051   1.00 52.56  ? 232 PHE A CE2 1 
ATOM   1824  C CZ  . PHE A 1 232 ? -42.558 7.709   -5.900   1.00 50.18  ? 232 PHE A CZ  1 
ATOM   1825  N N   . PHE A 1 233 ? -35.745 7.471   -7.363   1.00 46.93  ? 233 PHE A N   1 
ATOM   1826  C CA  . PHE A 1 233 ? -34.401 7.064   -7.736   1.00 40.24  ? 233 PHE A CA  1 
ATOM   1827  C C   . PHE A 1 233 ? -34.333 5.546   -7.718   1.00 48.39  ? 233 PHE A C   1 
ATOM   1828  O O   . PHE A 1 233 ? -35.199 4.876   -7.150   1.00 55.07  ? 233 PHE A O   1 
ATOM   1829  C CB  . PHE A 1 233 ? -33.348 7.658   -6.788   1.00 49.69  ? 233 PHE A CB  1 
ATOM   1830  C CG  . PHE A 1 233 ? -33.448 9.148   -6.637   1.00 58.38  ? 233 PHE A CG  1 
ATOM   1831  C CD1 . PHE A 1 233 ? -34.347 9.707   -5.744   1.00 55.69  ? 233 PHE A CD1 1 
ATOM   1832  C CD2 . PHE A 1 233 ? -32.649 9.990   -7.390   1.00 50.74  ? 233 PHE A CD2 1 
ATOM   1833  C CE1 . PHE A 1 233 ? -34.452 11.074  -5.612   1.00 48.99  ? 233 PHE A CE1 1 
ATOM   1834  C CE2 . PHE A 1 233 ? -32.748 11.360  -7.256   1.00 53.21  ? 233 PHE A CE2 1 
ATOM   1835  C CZ  . PHE A 1 233 ? -33.649 11.901  -6.364   1.00 43.50  ? 233 PHE A CZ  1 
ATOM   1836  N N   . TRP A 1 234 ? -33.299 5.004   -8.353   1.00 57.07  ? 234 TRP A N   1 
ATOM   1837  C CA  . TRP A 1 234 ? -33.147 3.560   -8.416   1.00 49.69  ? 234 TRP A CA  1 
ATOM   1838  C C   . TRP A 1 234 ? -31.673 3.200   -8.345   1.00 46.55  ? 234 TRP A C   1 
ATOM   1839  O O   . TRP A 1 234 ? -30.796 4.020   -8.628   1.00 51.67  ? 234 TRP A O   1 
ATOM   1840  C CB  . TRP A 1 234 ? -33.780 2.980   -9.688   1.00 41.78  ? 234 TRP A CB  1 
ATOM   1841  C CG  . TRP A 1 234 ? -33.182 3.509   -10.957  1.00 48.65  ? 234 TRP A CG  1 
ATOM   1842  C CD1 . TRP A 1 234 ? -33.516 4.665   -11.601  1.00 46.46  ? 234 TRP A CD1 1 
ATOM   1843  C CD2 . TRP A 1 234 ? -32.145 2.900   -11.737  1.00 43.36  ? 234 TRP A CD2 1 
ATOM   1844  N NE1 . TRP A 1 234 ? -32.750 4.815   -12.732  1.00 39.42  ? 234 TRP A NE1 1 
ATOM   1845  C CE2 . TRP A 1 234 ? -31.900 3.746   -12.839  1.00 43.09  ? 234 TRP A CE2 1 
ATOM   1846  C CE3 . TRP A 1 234 ? -31.398 1.725   -11.611  1.00 42.42  ? 234 TRP A CE3 1 
ATOM   1847  C CZ2 . TRP A 1 234 ? -30.943 3.451   -13.808  1.00 52.44  ? 234 TRP A CZ2 1 
ATOM   1848  C CZ3 . TRP A 1 234 ? -30.449 1.433   -12.576  1.00 46.34  ? 234 TRP A CZ3 1 
ATOM   1849  C CH2 . TRP A 1 234 ? -30.231 2.293   -13.660  1.00 49.41  ? 234 TRP A CH2 1 
ATOM   1850  N N   . THR A 1 235 ? -31.412 1.954   -7.952   1.00 46.08  ? 235 THR A N   1 
ATOM   1851  C CA  . THR A 1 235 ? -30.067 1.401   -7.979   1.00 37.29  ? 235 THR A CA  1 
ATOM   1852  C C   . THR A 1 235 ? -30.170 -0.107  -8.143   1.00 42.81  ? 235 THR A C   1 
ATOM   1853  O O   . THR A 1 235 ? -31.238 -0.700  -7.969   1.00 45.03  ? 235 THR A O   1 
ATOM   1854  C CB  . THR A 1 235 ? -29.269 1.750   -6.714   1.00 53.37  ? 235 THR A CB  1 
ATOM   1855  O OG1 . THR A 1 235 ? -27.874 1.527   -6.956   1.00 52.10  ? 235 THR A OG1 1 
ATOM   1856  C CG2 . THR A 1 235 ? -29.712 0.882   -5.541   1.00 44.09  ? 235 THR A CG2 1 
ATOM   1857  N N   . ILE A 1 236 ? -29.047 -0.718  -8.500   1.00 43.22  ? 236 ILE A N   1 
ATOM   1858  C CA  . ILE A 1 236 ? -28.930 -2.166  -8.620   1.00 46.56  ? 236 ILE A CA  1 
ATOM   1859  C C   . ILE A 1 236 ? -28.108 -2.652  -7.434   1.00 50.63  ? 236 ILE A C   1 
ATOM   1860  O O   . ILE A 1 236 ? -26.916 -2.342  -7.326   1.00 48.47  ? 236 ILE A O   1 
ATOM   1861  C CB  . ILE A 1 236 ? -28.284 -2.581  -9.949   1.00 48.08  ? 236 ILE A CB  1 
ATOM   1862  C CG1 . ILE A 1 236 ? -29.126 -2.096  -11.132  1.00 50.53  ? 236 ILE A CG1 1 
ATOM   1863  C CG2 . ILE A 1 236 ? -28.093 -4.089  -9.997   1.00 45.58  ? 236 ILE A CG2 1 
ATOM   1864  C CD1 . ILE A 1 236 ? -30.545 -2.622  -11.134  1.00 56.02  ? 236 ILE A CD1 1 
ATOM   1865  N N   . LEU A 1 237 ? -28.737 -3.411  -6.540   1.00 46.18  ? 237 LEU A N   1 
ATOM   1866  C CA  . LEU A 1 237 ? -28.056 -3.963  -5.373   1.00 46.66  ? 237 LEU A CA  1 
ATOM   1867  C C   . LEU A 1 237 ? -27.523 -5.343  -5.738   1.00 52.64  ? 237 LEU A C   1 
ATOM   1868  O O   . LEU A 1 237 ? -28.298 -6.282  -5.942   1.00 58.96  ? 237 LEU A O   1 
ATOM   1869  C CB  . LEU A 1 237 ? -29.000 -4.025  -4.175   1.00 43.70  ? 237 LEU A CB  1 
ATOM   1870  C CG  . LEU A 1 237 ? -28.354 -4.313  -2.819   1.00 60.52  ? 237 LEU A CG  1 
ATOM   1871  C CD1 . LEU A 1 237 ? -27.338 -3.234  -2.474   1.00 55.19  ? 237 LEU A CD1 1 
ATOM   1872  C CD2 . LEU A 1 237 ? -29.412 -4.426  -1.731   1.00 51.70  ? 237 LEU A CD2 1 
ATOM   1873  N N   . LYS A 1 238 ? -26.201 -5.464  -5.827   1.00 57.70  ? 238 LYS A N   1 
ATOM   1874  C CA  . LYS A 1 238 ? -25.589 -6.721  -6.227   1.00 62.16  ? 238 LYS A CA  1 
ATOM   1875  C C   . LYS A 1 238 ? -25.711 -7.744  -5.100   1.00 68.65  ? 238 LYS A C   1 
ATOM   1876  O O   . LYS A 1 238 ? -25.902 -7.377  -3.937   1.00 66.36  ? 238 LYS A O   1 
ATOM   1877  C CB  . LYS A 1 238 ? -24.125 -6.498  -6.598   1.00 58.40  ? 238 LYS A CB  1 
ATOM   1878  C CG  . LYS A 1 238 ? -23.924 -5.472  -7.703   1.00 60.80  ? 238 LYS A CG  1 
ATOM   1879  C CD  . LYS A 1 238 ? -22.877 -5.926  -8.710   1.00 72.15  ? 238 LYS A CD  1 
ATOM   1880  C CE  . LYS A 1 238 ? -23.437 -6.976  -9.666   1.00 86.07  ? 238 LYS A CE  1 
ATOM   1881  N NZ  . LYS A 1 238 ? -22.393 -7.537  -10.575  1.00 82.55  ? 238 LYS A NZ  1 
ATOM   1882  N N   . PRO A 1 239 ? -25.629 -9.037  -5.422   1.00 55.67  ? 239 PRO A N   1 
ATOM   1883  C CA  . PRO A 1 239 ? -25.761 -10.059 -4.380   1.00 60.77  ? 239 PRO A CA  1 
ATOM   1884  C C   . PRO A 1 239 ? -24.730 -9.888  -3.277   1.00 64.80  ? 239 PRO A C   1 
ATOM   1885  O O   . PRO A 1 239 ? -23.565 -9.582  -3.532   1.00 52.80  ? 239 PRO A O   1 
ATOM   1886  C CB  . PRO A 1 239 ? -25.561 -11.371 -5.147   1.00 56.03  ? 239 PRO A CB  1 
ATOM   1887  C CG  . PRO A 1 239 ? -25.990 -11.056 -6.532   1.00 58.95  ? 239 PRO A CG  1 
ATOM   1888  C CD  . PRO A 1 239 ? -25.554 -9.634  -6.766   1.00 45.62  ? 239 PRO A CD  1 
ATOM   1889  N N   . ASN A 1 240 ? -25.190 -10.088 -2.040   1.00 53.55  ? 240 ASN A N   1 
ATOM   1890  C CA  . ASN A 1 240 ? -24.435 -9.969  -0.794   1.00 60.44  ? 240 ASN A CA  1 
ATOM   1891  C C   . ASN A 1 240 ? -24.067 -8.533  -0.443   1.00 66.07  ? 240 ASN A C   1 
ATOM   1892  O O   . ASN A 1 240 ? -23.328 -8.317  0.523    1.00 67.52  ? 240 ASN A O   1 
ATOM   1893  C CB  . ASN A 1 240 ? -23.166 -10.830 -0.796   1.00 68.54  ? 240 ASN A CB  1 
ATOM   1894  C CG  . ASN A 1 240 ? -23.464 -12.298 -0.596   1.00 80.66  ? 240 ASN A CG  1 
ATOM   1895  O OD1 . ASN A 1 240 ? -23.798 -12.734 0.508    1.00 88.79  ? 240 ASN A OD1 1 
ATOM   1896  N ND2 . ASN A 1 240 ? -23.340 -13.075 -1.667   1.00 72.29  ? 240 ASN A ND2 1 
ATOM   1897  N N   . ASP A 1 241 ? -24.554 -7.549  -1.191   1.00 56.01  ? 241 ASP A N   1 
ATOM   1898  C CA  . ASP A 1 241 ? -24.435 -6.147  -0.822   1.00 61.27  ? 241 ASP A CA  1 
ATOM   1899  C C   . ASP A 1 241 ? -25.692 -5.713  -0.077   1.00 56.23  ? 241 ASP A C   1 
ATOM   1900  O O   . ASP A 1 241 ? -26.768 -6.297  -0.232   1.00 62.34  ? 241 ASP A O   1 
ATOM   1901  C CB  . ASP A 1 241 ? -24.221 -5.262  -2.058   1.00 52.89  ? 241 ASP A CB  1 
ATOM   1902  C CG  . ASP A 1 241 ? -23.719 -3.868  -1.703   1.00 65.90  ? 241 ASP A CG  1 
ATOM   1903  O OD1 . ASP A 1 241 ? -23.187 -3.688  -0.586   1.00 59.73  ? 241 ASP A OD1 1 
ATOM   1904  O OD2 . ASP A 1 241 ? -23.860 -2.950  -2.540   1.00 75.08  ? 241 ASP A OD2 1 
ATOM   1905  N N   . ALA A 1 242 ? -25.544 -4.677  0.742    1.00 51.47  ? 242 ALA A N   1 
ATOM   1906  C CA  . ALA A 1 242 ? -26.648 -4.153  1.530    1.00 50.70  ? 242 ALA A CA  1 
ATOM   1907  C C   . ALA A 1 242 ? -26.916 -2.698  1.169    1.00 58.12  ? 242 ALA A C   1 
ATOM   1908  O O   . ALA A 1 242 ? -26.010 -1.960  0.769    1.00 54.54  ? 242 ALA A O   1 
ATOM   1909  C CB  . ALA A 1 242 ? -26.369 -4.262  3.035    1.00 49.20  ? 242 ALA A CB  1 
ATOM   1910  N N   . ILE A 1 243 ? -28.175 -2.294  1.310    1.00 44.50  ? 243 ILE A N   1 
ATOM   1911  C CA  . ILE A 1 243 ? -28.592 -0.910  1.130    1.00 53.50  ? 243 ILE A CA  1 
ATOM   1912  C C   . ILE A 1 243 ? -29.049 -0.385  2.484    1.00 50.66  ? 243 ILE A C   1 
ATOM   1913  O O   . ILE A 1 243 ? -29.765 -1.077  3.219    1.00 54.68  ? 243 ILE A O   1 
ATOM   1914  C CB  . ILE A 1 243 ? -29.691 -0.780  0.057    1.00 56.68  ? 243 ILE A CB  1 
ATOM   1915  C CG1 . ILE A 1 243 ? -29.976 0.694   -0.249   1.00 51.31  ? 243 ILE A CG1 1 
ATOM   1916  C CG2 . ILE A 1 243 ? -30.967 -1.510  0.469    1.00 41.97  ? 243 ILE A CG2 1 
ATOM   1917  C CD1 . ILE A 1 243 ? -30.718 0.906   -1.558   1.00 38.77  ? 243 ILE A CD1 1 
ATOM   1918  N N   . HIS A 1 244 ? -28.595 0.815   2.836    1.00 51.01  ? 244 HIS A N   1 
ATOM   1919  C CA  . HIS A 1 244 ? -28.853 1.398   4.146    1.00 45.20  ? 244 HIS A CA  1 
ATOM   1920  C C   . HIS A 1 244 ? -29.632 2.690   3.961    1.00 53.06  ? 244 HIS A C   1 
ATOM   1921  O O   . HIS A 1 244 ? -29.174 3.598   3.260    1.00 56.98  ? 244 HIS A O   1 
ATOM   1922  C CB  . HIS A 1 244 ? -27.545 1.657   4.895    1.00 45.61  ? 244 HIS A CB  1 
ATOM   1923  C CG  . HIS A 1 244 ? -26.572 0.521   4.817    1.00 50.59  ? 244 HIS A CG  1 
ATOM   1924  N ND1 . HIS A 1 244 ? -26.546 -0.502  5.740    1.00 57.27  ? 244 HIS A ND1 1 
ATOM   1925  C CD2 . HIS A 1 244 ? -25.593 0.246   3.923    1.00 54.57  ? 244 HIS A CD2 1 
ATOM   1926  C CE1 . HIS A 1 244 ? -25.592 -1.358  5.418    1.00 48.59  ? 244 HIS A CE1 1 
ATOM   1927  N NE2 . HIS A 1 244 ? -24.998 -0.926  4.320    1.00 55.10  ? 244 HIS A NE2 1 
ATOM   1928  N N   . PHE A 1 245 ? -30.799 2.774   4.593    1.00 43.23  ? 245 PHE A N   1 
ATOM   1929  C CA  . PHE A 1 245 ? -31.662 3.941   4.505    1.00 40.08  ? 245 PHE A CA  1 
ATOM   1930  C C   . PHE A 1 245 ? -31.657 4.698   5.825    1.00 62.16  ? 245 PHE A C   1 
ATOM   1931  O O   . PHE A 1 245 ? -31.685 4.092   6.901    1.00 57.87  ? 245 PHE A O   1 
ATOM   1932  C CB  . PHE A 1 245 ? -33.100 3.547   4.151    1.00 51.13  ? 245 PHE A CB  1 
ATOM   1933  C CG  . PHE A 1 245 ? -33.267 3.036   2.748    1.00 47.37  ? 245 PHE A CG  1 
ATOM   1934  C CD1 . PHE A 1 245 ? -33.371 3.917   1.685    1.00 52.46  ? 245 PHE A CD1 1 
ATOM   1935  C CD2 . PHE A 1 245 ? -33.338 1.677   2.496    1.00 51.49  ? 245 PHE A CD2 1 
ATOM   1936  C CE1 . PHE A 1 245 ? -33.534 3.451   0.393    1.00 40.35  ? 245 PHE A CE1 1 
ATOM   1937  C CE2 . PHE A 1 245 ? -33.498 1.204   1.204    1.00 50.35  ? 245 PHE A CE2 1 
ATOM   1938  C CZ  . PHE A 1 245 ? -33.598 2.095   0.152    1.00 54.19  ? 245 PHE A CZ  1 
ATOM   1939  N N   . GLU A 1 246 ? -31.616 6.026   5.736    1.00 55.12  ? 246 GLU A N   1 
ATOM   1940  C CA  . GLU A 1 246 ? -31.771 6.884   6.901    1.00 47.55  ? 246 GLU A CA  1 
ATOM   1941  C C   . GLU A 1 246 ? -32.541 8.129   6.493    1.00 50.69  ? 246 GLU A C   1 
ATOM   1942  O O   . GLU A 1 246 ? -32.240 8.739   5.463    1.00 54.41  ? 246 GLU A O   1 
ATOM   1943  C CB  . GLU A 1 246 ? -30.416 7.262   7.513    1.00 52.76  ? 246 GLU A CB  1 
ATOM   1944  C CG  . GLU A 1 246 ? -30.526 8.185   8.722    1.00 54.25  ? 246 GLU A CG  1 
ATOM   1945  C CD  . GLU A 1 246 ? -29.288 8.159   9.602    1.00 75.02  ? 246 GLU A CD  1 
ATOM   1946  O OE1 . GLU A 1 246 ? -28.620 7.104   9.664    1.00 77.78  ? 246 GLU A OE1 1 
ATOM   1947  O OE2 . GLU A 1 246 ? -28.983 9.194   10.232   1.00 69.40  ? 246 GLU A OE2 1 
ATOM   1948  N N   . SER A 1 247 ? -33.537 8.494   7.295    1.00 55.05  ? 247 SER A N   1 
ATOM   1949  C CA  . SER A 1 247 ? -34.375 9.643   6.989    1.00 49.61  ? 247 SER A CA  1 
ATOM   1950  C C   . SER A 1 247 ? -35.153 10.038  8.234    1.00 61.52  ? 247 SER A C   1 
ATOM   1951  O O   . SER A 1 247 ? -35.446 9.200   9.089    1.00 65.78  ? 247 SER A O   1 
ATOM   1952  C CB  . SER A 1 247 ? -35.339 9.345   5.837    1.00 44.08  ? 247 SER A CB  1 
ATOM   1953  O OG  . SER A 1 247 ? -36.278 10.393  5.671    1.00 50.38  ? 247 SER A OG  1 
ATOM   1954  N N   . ASN A 1 248 ? -35.481 11.326  8.323    1.00 48.30  ? 248 ASN A N   1 
ATOM   1955  C CA  . ASN A 1 248 ? -36.363 11.841  9.362    1.00 51.79  ? 248 ASN A CA  1 
ATOM   1956  C C   . ASN A 1 248 ? -37.556 12.566  8.750    1.00 61.84  ? 248 ASN A C   1 
ATOM   1957  O O   . ASN A 1 248 ? -38.128 13.468  9.366    1.00 59.40  ? 248 ASN A O   1 
ATOM   1958  C CB  . ASN A 1 248 ? -35.604 12.755  10.324   1.00 51.87  ? 248 ASN A CB  1 
ATOM   1959  C CG  . ASN A 1 248 ? -35.001 13.957  9.633    1.00 62.88  ? 248 ASN A CG  1 
ATOM   1960  O OD1 . ASN A 1 248 ? -34.820 13.959  8.417    1.00 58.36  ? 248 ASN A OD1 1 
ATOM   1961  N ND2 . ASN A 1 248 ? -34.680 14.989  10.408   1.00 48.98  ? 248 ASN A ND2 1 
ATOM   1962  N N   . GLY A 1 249 ? -37.934 12.186  7.541    1.00 48.09  ? 249 GLY A N   1 
ATOM   1963  C CA  . GLY A 1 249 ? -39.110 12.746  6.904    1.00 56.14  ? 249 GLY A CA  1 
ATOM   1964  C C   . GLY A 1 249 ? -38.982 12.721  5.396    1.00 56.12  ? 249 GLY A C   1 
ATOM   1965  O O   . GLY A 1 249 ? -37.908 12.512  4.835    1.00 59.46  ? 249 GLY A O   1 
ATOM   1966  N N   . ASN A 1 250 ? -40.126 12.931  4.741    1.00 51.65  ? 250 ASN A N   1 
ATOM   1967  C CA  . ASN A 1 250 ? -40.240 13.058  3.288    1.00 55.52  ? 250 ASN A CA  1 
ATOM   1968  C C   . ASN A 1 250 ? -39.741 11.825  2.543    1.00 52.96  ? 250 ASN A C   1 
ATOM   1969  O O   . ASN A 1 250 ? -39.352 11.922  1.376    1.00 52.06  ? 250 ASN A O   1 
ATOM   1970  C CB  . ASN A 1 250 ? -39.508 14.308  2.786    1.00 49.39  ? 250 ASN A CB  1 
ATOM   1971  C CG  . ASN A 1 250 ? -39.951 15.569  3.500    1.00 51.67  ? 250 ASN A CG  1 
ATOM   1972  O OD1 . ASN A 1 250 ? -39.524 15.839  4.621    1.00 58.20  ? 250 ASN A OD1 1 
ATOM   1973  N ND2 . ASN A 1 250 ? -40.796 16.357  2.845    1.00 47.42  ? 250 ASN A ND2 1 
ATOM   1974  N N   . PHE A 1 251 ? -39.761 10.662  3.186    1.00 44.64  ? 251 PHE A N   1 
ATOM   1975  C CA  . PHE A 1 251 ? -39.163 9.447   2.644    1.00 38.36  ? 251 PHE A CA  1 
ATOM   1976  C C   . PHE A 1 251 ? -40.244 8.562   2.033    1.00 52.83  ? 251 PHE A C   1 
ATOM   1977  O O   . PHE A 1 251 ? -41.185 8.158   2.725    1.00 59.47  ? 251 PHE A O   1 
ATOM   1978  C CB  . PHE A 1 251 ? -38.402 8.706   3.745    1.00 43.58  ? 251 PHE A CB  1 
ATOM   1979  C CG  . PHE A 1 251 ? -37.737 7.438   3.290    1.00 49.42  ? 251 PHE A CG  1 
ATOM   1980  C CD1 . PHE A 1 251 ? -37.110 7.366   2.057    1.00 48.48  ? 251 PHE A CD1 1 
ATOM   1981  C CD2 . PHE A 1 251 ? -37.714 6.324   4.113    1.00 43.94  ? 251 PHE A CD2 1 
ATOM   1982  C CE1 . PHE A 1 251 ? -36.491 6.201   1.650    1.00 49.89  ? 251 PHE A CE1 1 
ATOM   1983  C CE2 . PHE A 1 251 ? -37.094 5.160   3.711    1.00 45.80  ? 251 PHE A CE2 1 
ATOM   1984  C CZ  . PHE A 1 251 ? -36.485 5.096   2.478    1.00 50.45  ? 251 PHE A CZ  1 
ATOM   1985  N N   . ILE A 1 252 ? -40.104 8.265   0.744    1.00 47.73  ? 252 ILE A N   1 
ATOM   1986  C CA  . ILE A 1 252 ? -40.991 7.336   0.042    1.00 43.83  ? 252 ILE A CA  1 
ATOM   1987  C C   . ILE A 1 252 ? -40.256 6.000   0.021    1.00 52.04  ? 252 ILE A C   1 
ATOM   1988  O O   . ILE A 1 252 ? -39.452 5.719   -0.868   1.00 49.78  ? 252 ILE A O   1 
ATOM   1989  C CB  . ILE A 1 252 ? -41.343 7.825   -1.362   1.00 50.04  ? 252 ILE A CB  1 
ATOM   1990  C CG1 . ILE A 1 252 ? -41.750 9.301   -1.335   1.00 47.13  ? 252 ILE A CG1 1 
ATOM   1991  C CG2 . ILE A 1 252 ? -42.462 6.979   -1.956   1.00 47.41  ? 252 ILE A CG2 1 
ATOM   1992  C CD1 . ILE A 1 252 ? -43.017 9.579   -0.562   1.00 53.26  ? 252 ILE A CD1 1 
ATOM   1993  N N   . ALA A 1 253 ? -40.537 5.166   1.019    1.00 50.34  ? 253 ALA A N   1 
ATOM   1994  C CA  . ALA A 1 253 ? -39.761 3.963   1.271    1.00 50.84  ? 253 ALA A CA  1 
ATOM   1995  C C   . ALA A 1 253 ? -40.125 2.845   0.296    1.00 53.42  ? 253 ALA A C   1 
ATOM   1996  O O   . ALA A 1 253 ? -41.260 2.771   -0.183   1.00 60.90  ? 253 ALA A O   1 
ATOM   1997  C CB  . ALA A 1 253 ? -39.986 3.484   2.700    1.00 47.77  ? 253 ALA A CB  1 
ATOM   1998  N N   . PRO A 1 254 ? -39.179 1.957   -0.006   1.00 51.26  ? 254 PRO A N   1 
ATOM   1999  C CA  . PRO A 1 254 ? -39.506 0.791   -0.829   1.00 53.16  ? 254 PRO A CA  1 
ATOM   2000  C C   . PRO A 1 254 ? -40.147 -0.309  0.000    1.00 61.53  ? 254 PRO A C   1 
ATOM   2001  O O   . PRO A 1 254 ? -39.789 -0.535  1.159    1.00 60.95  ? 254 PRO A O   1 
ATOM   2002  C CB  . PRO A 1 254 ? -38.142 0.342   -1.376   1.00 42.14  ? 254 PRO A CB  1 
ATOM   2003  C CG  . PRO A 1 254 ? -37.100 1.206   -0.682   1.00 48.35  ? 254 PRO A CG  1 
ATOM   2004  C CD  . PRO A 1 254 ? -37.776 1.927   0.436    1.00 43.84  ? 254 PRO A CD  1 
ATOM   2005  N N   . GLU A 1 255 ? -41.115 -0.989  -0.605   1.00 61.29  ? 255 GLU A N   1 
ATOM   2006  C CA  . GLU A 1 255 ? -41.644 -2.234  -0.066   1.00 62.23  ? 255 GLU A CA  1 
ATOM   2007  C C   . GLU A 1 255 ? -41.317 -3.433  -0.938   1.00 65.88  ? 255 GLU A C   1 
ATOM   2008  O O   . GLU A 1 255 ? -40.916 -4.478  -0.419   1.00 69.85  ? 255 GLU A O   1 
ATOM   2009  C CB  . GLU A 1 255 ? -43.165 -2.147  0.119    1.00 49.70  ? 255 GLU A CB  1 
ATOM   2010  C CG  . GLU A 1 255 ? -43.834 -3.515  0.065    1.00 82.44  ? 255 GLU A CG  1 
ATOM   2011  C CD  . GLU A 1 255 ? -45.149 -3.592  0.811    1.00 87.72  ? 255 GLU A CD  1 
ATOM   2012  O OE1 . GLU A 1 255 ? -46.049 -2.766  0.547    1.00 96.10  ? 255 GLU A OE1 1 
ATOM   2013  O OE2 . GLU A 1 255 ? -45.280 -4.493  1.666    1.00 84.17  ? 255 GLU A OE2 1 
ATOM   2014  N N   . TYR A 1 256 ? -41.463 -3.298  -2.254   1.00 66.47  ? 256 TYR A N   1 
ATOM   2015  C CA  . TYR A 1 256 ? -41.160 -4.358  -3.202   1.00 59.63  ? 256 TYR A CA  1 
ATOM   2016  C C   . TYR A 1 256 ? -39.955 -3.971  -4.048   1.00 54.95  ? 256 TYR A C   1 
ATOM   2017  O O   . TYR A 1 256 ? -39.793 -2.806  -4.425   1.00 66.11  ? 256 TYR A O   1 
ATOM   2018  C CB  . TYR A 1 256 ? -42.357 -4.648  -4.114   1.00 60.63  ? 256 TYR A CB  1 
ATOM   2019  C CG  . TYR A 1 256 ? -43.559 -5.226  -3.402   1.00 61.77  ? 256 TYR A CG  1 
ATOM   2020  C CD1 . TYR A 1 256 ? -43.591 -6.564  -3.027   1.00 60.76  ? 256 TYR A CD1 1 
ATOM   2021  C CD2 . TYR A 1 256 ? -44.668 -4.440  -3.118   1.00 65.17  ? 256 TYR A CD2 1 
ATOM   2022  C CE1 . TYR A 1 256 ? -44.690 -7.100  -2.377   1.00 66.41  ? 256 TYR A CE1 1 
ATOM   2023  C CE2 . TYR A 1 256 ? -45.772 -4.966  -2.468   1.00 76.54  ? 256 TYR A CE2 1 
ATOM   2024  C CZ  . TYR A 1 256 ? -45.777 -6.296  -2.100   1.00 72.12  ? 256 TYR A CZ  1 
ATOM   2025  O OH  . TYR A 1 256 ? -46.872 -6.824  -1.454   1.00 77.67  ? 256 TYR A OH  1 
ATOM   2026  N N   . ALA A 1 257 ? -39.112 -4.954  -4.335   1.00 63.93  ? 257 ALA A N   1 
ATOM   2027  C CA  . ALA A 1 257 ? -37.993 -4.825  -5.256   1.00 45.30  ? 257 ALA A CA  1 
ATOM   2028  C C   . ALA A 1 257 ? -38.134 -5.885  -6.344   1.00 52.70  ? 257 ALA A C   1 
ATOM   2029  O O   . ALA A 1 257 ? -39.076 -6.680  -6.345   1.00 55.31  ? 257 ALA A O   1 
ATOM   2030  C CB  . ALA A 1 257 ? -36.655 -4.954  -4.521   1.00 61.19  ? 257 ALA A CB  1 
ATOM   2031  N N   . TYR A 1 258 ? -37.188 -5.902  -7.279   1.00 55.89  ? 258 TYR A N   1 
ATOM   2032  C CA  . TYR A 1 258 ? -37.244 -6.818  -8.412   1.00 47.82  ? 258 TYR A CA  1 
ATOM   2033  C C   . TYR A 1 258 ? -35.924 -7.561  -8.539   1.00 49.54  ? 258 TYR A C   1 
ATOM   2034  O O   . TYR A 1 258 ? -34.869 -6.933  -8.672   1.00 56.73  ? 258 TYR A O   1 
ATOM   2035  C CB  . TYR A 1 258 ? -37.549 -6.069  -9.712   1.00 42.71  ? 258 TYR A CB  1 
ATOM   2036  C CG  . TYR A 1 258 ? -38.869 -5.331  -9.718   1.00 58.95  ? 258 TYR A CG  1 
ATOM   2037  C CD1 . TYR A 1 258 ? -40.062 -6.004  -9.951   1.00 50.44  ? 258 TYR A CD1 1 
ATOM   2038  C CD2 . TYR A 1 258 ? -38.921 -3.959  -9.507   1.00 55.79  ? 258 TYR A CD2 1 
ATOM   2039  C CE1 . TYR A 1 258 ? -41.270 -5.333  -9.967   1.00 46.98  ? 258 TYR A CE1 1 
ATOM   2040  C CE2 . TYR A 1 258 ? -40.125 -3.279  -9.522   1.00 51.19  ? 258 TYR A CE2 1 
ATOM   2041  C CZ  . TYR A 1 258 ? -41.295 -3.971  -9.752   1.00 55.64  ? 258 TYR A CZ  1 
ATOM   2042  O OH  . TYR A 1 258 ? -42.497 -3.301  -9.764   1.00 58.63  ? 258 TYR A OH  1 
ATOM   2043  N N   . LYS A 1 259 ? -35.984 -8.892  -8.508   1.00 50.74  ? 259 LYS A N   1 
ATOM   2044  C CA  . LYS A 1 259 ? -34.847 -9.687  -8.949   1.00 50.79  ? 259 LYS A CA  1 
ATOM   2045  C C   . LYS A 1 259 ? -34.722 -9.553  -10.459  1.00 62.15  ? 259 LYS A C   1 
ATOM   2046  O O   . LYS A 1 259 ? -35.699 -9.743  -11.190  1.00 61.86  ? 259 LYS A O   1 
ATOM   2047  C CB  . LYS A 1 259 ? -35.017 -11.155 -8.551   1.00 55.30  ? 259 LYS A CB  1 
ATOM   2048  C CG  . LYS A 1 259 ? -35.012 -11.398 -7.050   1.00 67.92  ? 259 LYS A CG  1 
ATOM   2049  C CD  . LYS A 1 259 ? -34.386 -12.739 -6.686   1.00 73.39  ? 259 LYS A CD  1 
ATOM   2050  C CE  . LYS A 1 259 ? -35.397 -13.871 -6.728   1.00 71.03  ? 259 LYS A CE  1 
ATOM   2051  N NZ  . LYS A 1 259 ? -34.837 -15.123 -6.143   1.00 90.56  ? 259 LYS A NZ  1 
ATOM   2052  N N   . ILE A 1 260 ? -33.529 -9.204  -10.931  1.00 48.45  ? 260 ILE A N   1 
ATOM   2053  C CA  . ILE A 1 260 ? -33.330 -8.863  -12.332  1.00 65.64  ? 260 ILE A CA  1 
ATOM   2054  C C   . ILE A 1 260 ? -32.086 -9.572  -12.848  1.00 56.07  ? 260 ILE A C   1 
ATOM   2055  O O   . ILE A 1 260 ? -31.026 -9.528  -12.213  1.00 60.02  ? 260 ILE A O   1 
ATOM   2056  C CB  . ILE A 1 260 ? -33.232 -7.336  -12.538  1.00 57.98  ? 260 ILE A CB  1 
ATOM   2057  C CG1 . ILE A 1 260 ? -32.996 -6.998  -14.011  1.00 50.67  ? 260 ILE A CG1 1 
ATOM   2058  C CG2 . ILE A 1 260 ? -32.158 -6.719  -11.642  1.00 46.98  ? 260 ILE A CG2 1 
ATOM   2059  C CD1 . ILE A 1 260 ? -32.979 -5.508  -14.290  1.00 62.42  ? 260 ILE A CD1 1 
ATOM   2060  N N   . VAL A 1 261 A -32.230 -10.254 -13.982  1.00 56.67  ? 260 VAL A N   1 
ATOM   2061  C CA  . VAL A 1 261 A -31.116 -10.850 -14.709  1.00 56.42  ? 260 VAL A CA  1 
ATOM   2062  C C   . VAL A 1 261 A -31.172 -10.317 -16.131  1.00 46.78  ? 260 VAL A C   1 
ATOM   2063  O O   . VAL A 1 261 A -32.205 -10.439 -16.800  1.00 59.74  ? 260 VAL A O   1 
ATOM   2064  C CB  . VAL A 1 261 A -31.171 -12.388 -14.709  1.00 65.16  ? 260 VAL A CB  1 
ATOM   2065  C CG1 . VAL A 1 261 A -29.917 -12.965 -15.346  1.00 60.38  ? 260 VAL A CG1 1 
ATOM   2066  C CG2 . VAL A 1 261 A -31.349 -12.914 -13.304  1.00 62.96  ? 260 VAL A CG2 1 
ATOM   2067  N N   . LYS A 1 262 ? -30.075 -9.726  -16.592  1.00 58.72  ? 261 LYS A N   1 
ATOM   2068  C CA  . LYS A 1 262 ? -29.988 -9.182  -17.939  1.00 56.06  ? 261 LYS A CA  1 
ATOM   2069  C C   . LYS A 1 262 ? -28.843 -9.859  -18.679  1.00 59.82  ? 261 LYS A C   1 
ATOM   2070  O O   . LYS A 1 262 ? -27.710 -9.886  -18.187  1.00 62.54  ? 261 LYS A O   1 
ATOM   2071  C CB  . LYS A 1 262 ? -29.785 -7.664  -17.909  1.00 60.74  ? 261 LYS A CB  1 
ATOM   2072  C CG  . LYS A 1 262 ? -29.789 -7.012  -19.280  1.00 57.39  ? 261 LYS A CG  1 
ATOM   2073  C CD  . LYS A 1 262 ? -29.587 -5.509  -19.181  1.00 54.30  ? 261 LYS A CD  1 
ATOM   2074  C CE  . LYS A 1 262 ? -29.482 -4.875  -20.559  1.00 50.59  ? 261 LYS A CE  1 
ATOM   2075  N NZ  . LYS A 1 262 ? -30.724 -5.055  -21.358  1.00 54.09  ? 261 LYS A NZ  1 
ATOM   2076  N N   . LYS A 1 263 ? -29.144 -10.410 -19.855  1.00 61.79  ? 262 LYS A N   1 
ATOM   2077  C CA  . LYS A 1 263 ? -28.142 -11.075 -20.674  1.00 54.22  ? 262 LYS A CA  1 
ATOM   2078  C C   . LYS A 1 263 ? -28.057 -10.535 -22.093  1.00 57.83  ? 262 LYS A C   1 
ATOM   2079  O O   . LYS A 1 263 ? -27.146 -10.932 -22.827  1.00 63.12  ? 262 LYS A O   1 
ATOM   2080  C CB  . LYS A 1 263 ? -28.412 -12.587 -20.731  1.00 60.85  ? 262 LYS A CB  1 
ATOM   2081  C CG  . LYS A 1 263 ? -28.407 -13.269 -19.367  1.00 64.15  ? 262 LYS A CG  1 
ATOM   2082  C CD  . LYS A 1 263 ? -28.832 -14.732 -19.448  1.00 80.72  ? 262 LYS A CD  1 
ATOM   2083  C CE  . LYS A 1 263 ? -27.660 -15.662 -19.741  1.00 93.28  ? 262 LYS A CE  1 
ATOM   2084  N NZ  . LYS A 1 263 ? -27.166 -15.559 -21.142  1.00 89.78  ? 262 LYS A NZ  1 
ATOM   2085  N N   . GLY A 1 264 ? -28.964 -9.646  -22.501  1.00 58.12  ? 263 GLY A N   1 
ATOM   2086  C CA  . GLY A 1 264 ? -28.941 -9.085  -23.836  1.00 60.32  ? 263 GLY A CA  1 
ATOM   2087  C C   . GLY A 1 264 ? -29.611 -7.728  -23.857  1.00 62.22  ? 263 GLY A C   1 
ATOM   2088  O O   . GLY A 1 264 ? -30.276 -7.322  -22.901  1.00 54.58  ? 263 GLY A O   1 
ATOM   2089  N N   . ASP A 1 265 ? -29.440 -7.032  -24.977  1.00 63.36  ? 264 ASP A N   1 
ATOM   2090  C CA  . ASP A 1 265 ? -29.900 -5.660  -25.130  1.00 63.39  ? 264 ASP A CA  1 
ATOM   2091  C C   . ASP A 1 265 ? -30.973 -5.567  -26.207  1.00 61.76  ? 264 ASP A C   1 
ATOM   2092  O O   . ASP A 1 265 ? -31.005 -6.360  -27.153  1.00 60.88  ? 264 ASP A O   1 
ATOM   2093  C CB  . ASP A 1 265 ? -28.738 -4.726  -25.487  1.00 58.84  ? 264 ASP A CB  1 
ATOM   2094  C CG  . ASP A 1 265 ? -27.548 -4.898  -24.564  1.00 84.34  ? 264 ASP A CG  1 
ATOM   2095  O OD1 . ASP A 1 265 ? -27.754 -4.986  -23.335  1.00 82.65  ? 264 ASP A OD1 1 
ATOM   2096  O OD2 . ASP A 1 265 ? -26.406 -4.952  -25.070  1.00 86.64  ? 264 ASP A OD2 1 
ATOM   2097  N N   . SER A 1 266 ? -31.854 -4.588  -26.044  1.00 62.65  ? 265 SER A N   1 
ATOM   2098  C CA  . SER A 1 266 ? -32.939 -4.309  -26.978  1.00 57.80  ? 265 SER A CA  1 
ATOM   2099  C C   . SER A 1 266 ? -33.242 -2.817  -26.895  1.00 59.76  ? 265 SER A C   1 
ATOM   2100  O O   . SER A 1 266 ? -32.392 -2.023  -26.479  1.00 61.28  ? 265 SER A O   1 
ATOM   2101  C CB  . SER A 1 266 ? -34.160 -5.191  -26.671  1.00 46.81  ? 265 SER A CB  1 
ATOM   2102  O OG  . SER A 1 266 ? -35.183 -4.980  -27.625  1.00 54.81  ? 265 SER A OG  1 
ATOM   2103  N N   . THR A 1 267 ? -34.433 -2.422  -27.336  1.00 49.25  ? 266 THR A N   1 
ATOM   2104  C CA  . THR A 1 267 ? -34.906 -1.062  -27.120  1.00 52.76  ? 266 THR A CA  1 
ATOM   2105  C C   . THR A 1 267 ? -36.411 -1.094  -26.885  1.00 49.15  ? 266 THR A C   1 
ATOM   2106  O O   . THR A 1 267 ? -37.043 -2.155  -26.907  1.00 46.94  ? 266 THR A O   1 
ATOM   2107  C CB  . THR A 1 267 ? -34.548 -0.152  -28.298  1.00 72.37  ? 266 THR A CB  1 
ATOM   2108  O OG1 . THR A 1 267 ? -34.851 1.208   -27.961  1.00 59.41  ? 266 THR A OG1 1 
ATOM   2109  C CG2 . THR A 1 267 ? -35.341 -0.546  -29.530  1.00 48.42  ? 266 THR A CG2 1 
ATOM   2110  N N   . ILE A 1 268 ? -36.981 0.084   -26.643  1.00 45.69  ? 267 ILE A N   1 
ATOM   2111  C CA  . ILE A 1 268 ? -38.421 0.242   -26.476  1.00 51.92  ? 267 ILE A CA  1 
ATOM   2112  C C   . ILE A 1 268 ? -39.032 0.593   -27.825  1.00 67.20  ? 267 ILE A C   1 
ATOM   2113  O O   . ILE A 1 268 ? -38.533 1.475   -28.534  1.00 63.01  ? 267 ILE A O   1 
ATOM   2114  C CB  . ILE A 1 268 ? -38.745 1.321   -25.428  1.00 48.63  ? 267 ILE A CB  1 
ATOM   2115  C CG1 . ILE A 1 268 ? -38.316 0.870   -24.029  1.00 64.09  ? 267 ILE A CG1 1 
ATOM   2116  C CG2 . ILE A 1 268 ? -40.227 1.656   -25.441  1.00 43.02  ? 267 ILE A CG2 1 
ATOM   2117  C CD1 . ILE A 1 268 ? -36.997 1.456   -23.574  1.00 69.87  ? 267 ILE A CD1 1 
ATOM   2118  N N   . MET A 1 269 ? -40.111 -0.096  -28.183  1.00 55.01  ? 268 MET A N   1 
ATOM   2119  C CA  . MET A 1 269 ? -40.818 0.147   -29.432  1.00 54.64  ? 268 MET A CA  1 
ATOM   2120  C C   . MET A 1 269 ? -42.112 0.902   -29.153  1.00 58.21  ? 268 MET A C   1 
ATOM   2121  O O   . MET A 1 269 ? -42.888 0.512   -28.274  1.00 55.82  ? 268 MET A O   1 
ATOM   2122  C CB  . MET A 1 269 ? -41.113 -1.171  -30.152  1.00 49.93  ? 268 MET A CB  1 
ATOM   2123  C CG  . MET A 1 269 ? -42.001 -1.034  -31.377  1.00 64.28  ? 268 MET A CG  1 
ATOM   2124  S SD  . MET A 1 269 ? -42.161 -2.584  -32.282  1.00 67.32  ? 268 MET A SD  1 
ATOM   2125  C CE  . MET A 1 269 ? -40.518 -2.739  -32.979  1.00 51.66  ? 268 MET A CE  1 
ATOM   2126  N N   . LYS A 1 270 ? -42.332 1.987   -29.891  1.00 49.12  ? 269 LYS A N   1 
ATOM   2127  C CA  . LYS A 1 270 ? -43.578 2.743   -29.819  1.00 64.92  ? 269 LYS A CA  1 
ATOM   2128  C C   . LYS A 1 270 ? -44.521 2.205   -30.889  1.00 63.58  ? 269 LYS A C   1 
ATOM   2129  O O   . LYS A 1 270 ? -44.279 2.384   -32.087  1.00 70.20  ? 269 LYS A O   1 
ATOM   2130  C CB  . LYS A 1 270 ? -43.319 4.235   -30.010  1.00 59.32  ? 269 LYS A CB  1 
ATOM   2131  C CG  . LYS A 1 270 ? -42.460 4.871   -28.927  1.00 53.72  ? 269 LYS A CG  1 
ATOM   2132  C CD  . LYS A 1 270 ? -43.197 4.940   -27.600  1.00 64.88  ? 269 LYS A CD  1 
ATOM   2133  C CE  . LYS A 1 270 ? -42.457 5.820   -26.602  1.00 59.93  ? 269 LYS A CE  1 
ATOM   2134  N NZ  . LYS A 1 270 ? -43.208 5.962   -25.321  1.00 54.91  ? 269 LYS A NZ  1 
ATOM   2135  N N   . SER A 1 271 ? -45.592 1.539   -30.461  1.00 67.07  ? 270 SER A N   1 
ATOM   2136  C CA  . SER A 1 271 ? -46.517 0.932   -31.406  1.00 74.06  ? 270 SER A CA  1 
ATOM   2137  C C   . SER A 1 271 ? -47.866 0.722   -30.735  1.00 71.79  ? 270 SER A C   1 
ATOM   2138  O O   . SER A 1 271 ? -47.943 0.433   -29.537  1.00 64.44  ? 270 SER A O   1 
ATOM   2139  C CB  . SER A 1 271 ? -45.981 -0.402  -31.939  1.00 65.89  ? 270 SER A CB  1 
ATOM   2140  O OG  . SER A 1 271 ? -46.977 -1.090  -32.675  1.00 60.02  ? 270 SER A OG  1 
ATOM   2141  N N   . GLY A 1 272 ? -48.924 0.867   -31.528  1.00 67.03  ? 271 GLY A N   1 
ATOM   2142  C CA  . GLY A 1 272 ? -50.269 0.586   -31.072  1.00 63.21  ? 271 GLY A CA  1 
ATOM   2143  C C   . GLY A 1 272 ? -50.794 -0.707  -31.659  1.00 58.26  ? 271 GLY A C   1 
ATOM   2144  O O   . GLY A 1 272 ? -51.939 -1.096  -31.411  1.00 69.81  ? 271 GLY A O   1 
ATOM   2145  N N   . VAL A 1 273 ? -49.956 -1.374  -32.455  1.00 71.10  ? 272 VAL A N   1 
ATOM   2146  C CA  . VAL A 1 273 ? -50.342 -2.647  -33.046  1.00 62.49  ? 272 VAL A CA  1 
ATOM   2147  C C   . VAL A 1 273 ? -50.515 -3.691  -31.946  1.00 72.59  ? 272 VAL A C   1 
ATOM   2148  O O   . VAL A 1 273 ? -49.868 -3.643  -30.892  1.00 77.51  ? 272 VAL A O   1 
ATOM   2149  C CB  . VAL A 1 273 ? -49.313 -3.086  -34.106  1.00 61.21  ? 272 VAL A CB  1 
ATOM   2150  C CG1 . VAL A 1 273 ? -49.602 -4.488  -34.627  1.00 58.42  ? 272 VAL A CG1 1 
ATOM   2151  C CG2 . VAL A 1 273 ? -49.318 -2.102  -35.265  1.00 66.21  ? 272 VAL A CG2 1 
ATOM   2152  N N   . GLU A 1 274 ? -51.417 -4.633  -32.192  1.00 74.40  ? 273 GLU A N   1 
ATOM   2153  C CA  . GLU A 1 274 ? -51.814 -5.659  -31.246  1.00 70.11  ? 273 GLU A CA  1 
ATOM   2154  C C   . GLU A 1 274 ? -50.974 -6.921  -31.428  1.00 72.44  ? 273 GLU A C   1 
ATOM   2155  O O   . GLU A 1 274 ? -50.458 -7.200  -32.515  1.00 62.82  ? 273 GLU A O   1 
ATOM   2156  C CB  . GLU A 1 274 ? -53.304 -5.967  -31.430  1.00 73.46  ? 273 GLU A CB  1 
ATOM   2157  C CG  . GLU A 1 274 ? -53.724 -6.353  -32.876  1.00 92.37  ? 273 GLU A CG  1 
ATOM   2158  C CD  . GLU A 1 274 ? -53.752 -5.189  -33.881  1.00 99.55  ? 273 GLU A CD  1 
ATOM   2159  O OE1 . GLU A 1 274 ? -54.614 -5.214  -34.791  1.00 97.40  ? 273 GLU A OE1 1 
ATOM   2160  O OE2 . GLU A 1 274 ? -52.916 -4.269  -33.785  1.00 98.31  ? 273 GLU A OE2 1 
ATOM   2161  N N   . TYR A 1 275 ? -50.831 -7.678  -30.343  1.00 67.40  ? 274 TYR A N   1 
ATOM   2162  C CA  . TYR A 1 275 ? -50.060 -8.913  -30.378  1.00 70.46  ? 274 TYR A CA  1 
ATOM   2163  C C   . TYR A 1 275 ? -50.752 -9.947  -31.262  1.00 75.48  ? 274 TYR A C   1 
ATOM   2164  O O   . TYR A 1 275 ? -51.982 -10.020 -31.324  1.00 73.57  ? 274 TYR A O   1 
ATOM   2165  C CB  . TYR A 1 275 ? -49.871 -9.455  -28.961  1.00 68.49  ? 274 TYR A CB  1 
ATOM   2166  C CG  . TYR A 1 275 ? -49.012 -10.694 -28.866  1.00 67.08  ? 274 TYR A CG  1 
ATOM   2167  C CD1 . TYR A 1 275 ? -47.665 -10.659 -29.202  1.00 60.60  ? 274 TYR A CD1 1 
ATOM   2168  C CD2 . TYR A 1 275 ? -49.544 -11.895 -28.417  1.00 69.53  ? 274 TYR A CD2 1 
ATOM   2169  C CE1 . TYR A 1 275 ? -46.877 -11.790 -29.109  1.00 58.71  ? 274 TYR A CE1 1 
ATOM   2170  C CE2 . TYR A 1 275 ? -48.764 -13.030 -28.319  1.00 65.83  ? 274 TYR A CE2 1 
ATOM   2171  C CZ  . TYR A 1 275 ? -47.432 -12.973 -28.666  1.00 73.27  ? 274 TYR A CZ  1 
ATOM   2172  O OH  . TYR A 1 275 ? -46.654 -14.105 -28.567  1.00 60.46  ? 274 TYR A OH  1 
ATOM   2173  N N   . GLY A 1 276 ? -49.947 -10.748 -31.957  1.00 71.94  ? 275 GLY A N   1 
ATOM   2174  C CA  . GLY A 1 276 ? -50.486 -11.641 -32.966  1.00 78.80  ? 275 GLY A CA  1 
ATOM   2175  C C   . GLY A 1 276 ? -50.186 -13.116 -32.785  1.00 84.50  ? 275 GLY A C   1 
ATOM   2176  O O   . GLY A 1 276 ? -50.507 -13.920 -33.666  1.00 93.46  ? 275 GLY A O   1 
ATOM   2177  N N   . HIS A 1 277 ? -49.582 -13.487 -31.655  1.00 78.96  ? 276 HIS A N   1 
ATOM   2178  C CA  . HIS A 1 277 ? -49.245 -14.881 -31.356  1.00 81.65  ? 276 HIS A CA  1 
ATOM   2179  C C   . HIS A 1 277 ? -48.408 -15.500 -32.476  1.00 78.15  ? 276 HIS A C   1 
ATOM   2180  O O   . HIS A 1 277 ? -48.680 -16.600 -32.961  1.00 90.81  ? 276 HIS A O   1 
ATOM   2181  C CB  . HIS A 1 277 ? -50.506 -15.705 -31.093  1.00 80.67  ? 276 HIS A CB  1 
ATOM   2182  C CG  . HIS A 1 277 ? -51.337 -15.189 -29.960  1.00 82.92  ? 276 HIS A CG  1 
ATOM   2183  N ND1 . HIS A 1 277 ? -51.230 -15.677 -28.676  1.00 82.61  ? 276 HIS A ND1 1 
ATOM   2184  C CD2 . HIS A 1 277 ? -52.286 -14.224 -29.919  1.00 75.46  ? 276 HIS A CD2 1 
ATOM   2185  C CE1 . HIS A 1 277 ? -52.079 -15.036 -27.892  1.00 79.13  ? 276 HIS A CE1 1 
ATOM   2186  N NE2 . HIS A 1 277 ? -52.732 -14.150 -28.621  1.00 82.87  ? 276 HIS A NE2 1 
ATOM   2187  N N   . CYS A 1 278 ? -47.373 -14.772 -32.884  1.00 80.93  ? 277 CYS A N   1 
ATOM   2188  C CA  . CYS A 1 278 ? -46.485 -15.165 -33.967  1.00 67.39  ? 277 CYS A CA  1 
ATOM   2189  C C   . CYS A 1 278 ? -45.041 -15.055 -33.497  1.00 69.80  ? 277 CYS A C   1 
ATOM   2190  O O   . CYS A 1 278 ? -44.755 -14.542 -32.412  1.00 77.61  ? 277 CYS A O   1 
ATOM   2191  C CB  . CYS A 1 278 ? -46.714 -14.293 -35.209  1.00 70.12  ? 277 CYS A CB  1 
ATOM   2192  S SG  . CYS A 1 278 ? -47.082 -12.561 -34.812  1.00 115.00 ? 277 CYS A SG  1 
ATOM   2193  N N   . ASN A 1 279 ? -44.122 -15.548 -34.323  1.00 68.15  ? 278 ASN A N   1 
ATOM   2194  C CA  . ASN A 1 279 ? -42.700 -15.441 -34.038  1.00 63.86  ? 278 ASN A CA  1 
ATOM   2195  C C   . ASN A 1 279 ? -41.975 -14.871 -35.248  1.00 73.83  ? 278 ASN A C   1 
ATOM   2196  O O   . ASN A 1 279 ? -42.349 -15.125 -36.397  1.00 68.50  ? 278 ASN A O   1 
ATOM   2197  C CB  . ASN A 1 279 ? -42.088 -16.794 -33.656  1.00 59.79  ? 278 ASN A CB  1 
ATOM   2198  C CG  . ASN A 1 279 ? -40.678 -16.660 -33.109  1.00 79.50  ? 278 ASN A CG  1 
ATOM   2199  O OD1 . ASN A 1 279 ? -40.318 -15.632 -32.532  1.00 76.78  ? 278 ASN A OD1 1 
ATOM   2200  N ND2 . ASN A 1 279 ? -39.871 -17.698 -33.289  1.00 75.40  ? 278 ASN A ND2 1 
ATOM   2201  N N   . THR A 1 280 ? -40.929 -14.097 -34.973  1.00 71.20  ? 279 THR A N   1 
ATOM   2202  C CA  . THR A 1 280 ? -40.138 -13.471 -36.021  1.00 64.32  ? 279 THR A CA  1 
ATOM   2203  C C   . THR A 1 280 ? -38.753 -13.169 -35.471  1.00 60.52  ? 279 THR A C   1 
ATOM   2204  O O   . THR A 1 280 ? -38.540 -13.137 -34.256  1.00 71.55  ? 279 THR A O   1 
ATOM   2205  C CB  . THR A 1 280 ? -40.796 -12.187 -36.535  1.00 75.95  ? 279 THR A CB  1 
ATOM   2206  O OG1 . THR A 1 280 ? -40.007 -11.634 -37.597  1.00 70.39  ? 279 THR A OG1 1 
ATOM   2207  C CG2 . THR A 1 280 ? -40.909 -11.165 -35.411  1.00 75.51  ? 279 THR A CG2 1 
ATOM   2208  N N   . LYS A 1 281 ? -37.810 -12.956 -36.386  1.00 54.91  ? 280 LYS A N   1 
ATOM   2209  C CA  . LYS A 1 281 ? -36.485 -12.463 -36.034  1.00 70.71  ? 280 LYS A CA  1 
ATOM   2210  C C   . LYS A 1 281 ? -36.289 -11.008 -36.442  1.00 64.00  ? 280 LYS A C   1 
ATOM   2211  O O   . LYS A 1 281 ? -35.174 -10.488 -36.335  1.00 66.07  ? 280 LYS A O   1 
ATOM   2212  C CB  . LYS A 1 281 ? -35.400 -13.350 -36.655  1.00 63.30  ? 280 LYS A CB  1 
ATOM   2213  C CG  . LYS A 1 281 ? -35.729 -13.877 -38.037  1.00 77.93  ? 280 LYS A CG  1 
ATOM   2214  C CD  . LYS A 1 281 ? -35.583 -12.794 -39.070  1.00 78.71  ? 280 LYS A CD  1 
ATOM   2215  C CE  . LYS A 1 281 ? -36.294 -13.148 -40.347  1.00 96.12  ? 280 LYS A CE  1 
ATOM   2216  N NZ  . LYS A 1 281 ? -36.264 -11.953 -41.217  1.00 76.78  ? 280 LYS A NZ  1 
ATOM   2217  N N   . CYS A 1 282 ? -37.346 -10.346 -36.912  1.00 61.48  ? 281 CYS A N   1 
ATOM   2218  C CA  . CYS A 1 282 ? -37.274 -8.941  -37.307  1.00 64.53  ? 281 CYS A CA  1 
ATOM   2219  C C   . CYS A 1 282 ? -38.649 -8.323  -37.098  1.00 71.34  ? 281 CYS A C   1 
ATOM   2220  O O   . CYS A 1 282 ? -39.608 -8.697  -37.781  1.00 65.56  ? 281 CYS A O   1 
ATOM   2221  C CB  . CYS A 1 282 ? -36.823 -8.797  -38.758  1.00 63.89  ? 281 CYS A CB  1 
ATOM   2222  S SG  . CYS A 1 282 ? -36.954 -7.105  -39.380  1.00 82.26  ? 281 CYS A SG  1 
ATOM   2223  N N   . GLN A 1 283 ? -38.745 -7.379  -36.166  1.00 71.48  ? 282 GLN A N   1 
ATOM   2224  C CA  . GLN A 1 283 ? -40.004 -6.735  -35.822  1.00 50.67  ? 282 GLN A CA  1 
ATOM   2225  C C   . GLN A 1 283 ? -39.946 -5.254  -36.174  1.00 61.67  ? 282 GLN A C   1 
ATOM   2226  O O   . GLN A 1 283 ? -38.904 -4.609  -36.018  1.00 60.70  ? 282 GLN A O   1 
ATOM   2227  C CB  . GLN A 1 283 ? -40.318 -6.905  -34.330  1.00 51.88  ? 282 GLN A CB  1 
ATOM   2228  C CG  . GLN A 1 283 ? -41.675 -6.358  -33.912  1.00 59.27  ? 282 GLN A CG  1 
ATOM   2229  C CD  . GLN A 1 283 ? -42.827 -7.126  -34.532  1.00 64.12  ? 282 GLN A CD  1 
ATOM   2230  O OE1 . GLN A 1 283 ? -42.937 -8.341  -34.364  1.00 63.42  ? 282 GLN A OE1 1 
ATOM   2231  N NE2 . GLN A 1 283 ? -43.688 -6.422  -35.259  1.00 50.70  ? 282 GLN A NE2 1 
ATOM   2232  N N   . THR A 1 284 ? -41.063 -4.726  -36.653  1.00 59.12  ? 283 THR A N   1 
ATOM   2233  C CA  . THR A 1 284 ? -41.244 -3.311  -36.931  1.00 56.04  ? 283 THR A CA  1 
ATOM   2234  C C   . THR A 1 284 ? -42.500 -2.839  -36.217  1.00 57.72  ? 283 THR A C   1 
ATOM   2235  O O   . THR A 1 284 ? -43.360 -3.651  -35.860  1.00 56.16  ? 283 THR A O   1 
ATOM   2236  C CB  . THR A 1 284 ? -41.363 -3.032  -38.439  1.00 58.74  ? 283 THR A CB  1 
ATOM   2237  O OG1 . THR A 1 284 ? -42.629 -3.498  -38.919  1.00 72.59  ? 283 THR A OG1 1 
ATOM   2238  C CG2 . THR A 1 284 ? -40.245 -3.726  -39.205  1.00 60.42  ? 283 THR A CG2 1 
ATOM   2239  N N   . PRO A 1 285 ? -42.629 -1.532  -35.971  1.00 53.20  ? 284 PRO A N   1 
ATOM   2240  C CA  . PRO A 1 285 ? -43.837 -1.035  -35.290  1.00 53.35  ? 284 PRO A CA  1 
ATOM   2241  C C   . PRO A 1 285 ? -45.125 -1.290  -36.054  1.00 67.24  ? 284 PRO A C   1 
ATOM   2242  O O   . PRO A 1 285 ? -46.201 -1.236  -35.447  1.00 63.53  ? 284 PRO A O   1 
ATOM   2243  C CB  . PRO A 1 285 ? -43.564 0.469   -35.145  1.00 62.07  ? 284 PRO A CB  1 
ATOM   2244  C CG  . PRO A 1 285 ? -42.078 0.585   -35.171  1.00 49.79  ? 284 PRO A CG  1 
ATOM   2245  C CD  . PRO A 1 285 ? -41.613 -0.474  -36.124  1.00 56.21  ? 284 PRO A CD  1 
ATOM   2246  N N   . VAL A 1 286 ? -45.060 -1.556  -37.362  1.00 65.91  ? 285 VAL A N   1 
ATOM   2247  C CA  . VAL A 1 286 ? -46.265 -1.810  -38.148  1.00 56.34  ? 285 VAL A CA  1 
ATOM   2248  C C   . VAL A 1 286 ? -46.486 -3.289  -38.435  1.00 62.53  ? 285 VAL A C   1 
ATOM   2249  O O   . VAL A 1 286 ? -47.590 -3.664  -38.861  1.00 63.34  ? 285 VAL A O   1 
ATOM   2250  C CB  . VAL A 1 286 ? -46.246 -1.024  -39.477  1.00 56.08  ? 285 VAL A CB  1 
ATOM   2251  C CG1 . VAL A 1 286 ? -45.854 0.424   -39.231  1.00 53.15  ? 285 VAL A CG1 1 
ATOM   2252  C CG2 . VAL A 1 286 ? -45.307 -1.682  -40.475  1.00 62.79  ? 285 VAL A CG2 1 
ATOM   2253  N N   . GLY A 1 287 ? -45.489 -4.133  -38.222  1.00 63.24  ? 286 GLY A N   1 
ATOM   2254  C CA  . GLY A 1 287 ? -45.650 -5.556  -38.434  1.00 54.47  ? 286 GLY A CA  1 
ATOM   2255  C C   . GLY A 1 287 ? -44.319 -6.264  -38.492  1.00 60.14  ? 286 GLY A C   1 
ATOM   2256  O O   . GLY A 1 287 ? -43.261 -5.659  -38.672  1.00 60.60  ? 286 GLY A O   1 
ATOM   2257  N N   . ALA A 1 288 ? -44.380 -7.583  -38.335  1.00 54.84  ? 287 ALA A N   1 
ATOM   2258  C CA  . ALA A 1 288 ? -43.187 -8.410  -38.403  1.00 57.73  ? 287 ALA A CA  1 
ATOM   2259  C C   . ALA A 1 288 ? -42.816 -8.698  -39.855  1.00 66.18  ? 287 ALA A C   1 
ATOM   2260  O O   . ALA A 1 288 ? -43.638 -8.601  -40.768  1.00 75.39  ? 287 ALA A O   1 
ATOM   2261  C CB  . ALA A 1 288 ? -43.393 -9.721  -37.646  1.00 47.53  ? 287 ALA A CB  1 
ATOM   2262  N N   . ILE A 1 289 ? -41.557 -9.074  -40.055  1.00 68.54  ? 288 ILE A N   1 
ATOM   2263  C CA  . ILE A 1 289 ? -40.991 -9.287  -41.381  1.00 58.57  ? 288 ILE A CA  1 
ATOM   2264  C C   . ILE A 1 289 ? -40.431 -10.701 -41.448  1.00 61.68  ? 288 ILE A C   1 
ATOM   2265  O O   . ILE A 1 289 ? -39.620 -11.095 -40.602  1.00 72.43  ? 288 ILE A O   1 
ATOM   2266  C CB  . ILE A 1 289 ? -39.911 -8.235  -41.698  1.00 61.28  ? 288 ILE A CB  1 
ATOM   2267  C CG1 . ILE A 1 289 ? -40.549 -6.969  -42.265  1.00 58.52  ? 288 ILE A CG1 1 
ATOM   2268  C CG2 . ILE A 1 289 ? -38.887 -8.764  -42.676  1.00 65.87  ? 288 ILE A CG2 1 
ATOM   2269  C CD1 . ILE A 1 289 ? -39.587 -5.809  -42.351  1.00 66.92  ? 288 ILE A CD1 1 
ATOM   2270  N N   . ASN A 1 290 ? -40.881 -11.465 -42.443  1.00 65.61  ? 289 ASN A N   1 
ATOM   2271  C CA  . ASN A 1 290 ? -40.403 -12.822 -42.703  1.00 64.69  ? 289 ASN A CA  1 
ATOM   2272  C C   . ASN A 1 290 ? -39.859 -12.832 -44.129  1.00 78.89  ? 289 ASN A C   1 
ATOM   2273  O O   . ASN A 1 290 ? -40.624 -12.941 -45.092  1.00 79.27  ? 289 ASN A O   1 
ATOM   2274  C CB  . ASN A 1 290 ? -41.519 -13.847 -42.513  1.00 65.47  ? 289 ASN A CB  1 
ATOM   2275  C CG  . ASN A 1 290 ? -41.034 -15.273 -42.684  1.00 77.64  ? 289 ASN A CG  1 
ATOM   2276  O OD1 . ASN A 1 290 ? -39.844 -15.554 -42.551  1.00 75.09  ? 289 ASN A OD1 1 
ATOM   2277  N ND2 . ASN A 1 290 ? -41.957 -16.182 -42.980  1.00 84.82  ? 289 ASN A ND2 1 
ATOM   2278  N N   . SER A 1 291 ? -38.540 -12.713 -44.265  1.00 74.16  ? 290 SER A N   1 
ATOM   2279  C CA  . SER A 1 291 ? -37.934 -12.480 -45.569  1.00 73.90  ? 290 SER A CA  1 
ATOM   2280  C C   . SER A 1 291 ? -36.457 -12.837 -45.520  1.00 73.51  ? 290 SER A C   1 
ATOM   2281  O O   . SER A 1 291 ? -35.864 -12.984 -44.447  1.00 83.08  ? 290 SER A O   1 
ATOM   2282  C CB  . SER A 1 291 ? -38.110 -11.021 -46.002  1.00 74.72  ? 290 SER A CB  1 
ATOM   2283  O OG  . SER A 1 291 ? -37.264 -10.699 -47.092  1.00 71.43  ? 290 SER A OG  1 
ATOM   2284  N N   . SER A 1 292 ? -35.874 -12.974 -46.709  1.00 73.11  ? 291 SER A N   1 
ATOM   2285  C CA  . SER A 1 292 ? -34.436 -13.108 -46.878  1.00 73.32  ? 291 SER A CA  1 
ATOM   2286  C C   . SER A 1 292 ? -33.856 -12.003 -47.747  1.00 64.46  ? 291 SER A C   1 
ATOM   2287  O O   . SER A 1 292 ? -32.650 -12.017 -48.020  1.00 62.74  ? 291 SER A O   1 
ATOM   2288  C CB  . SER A 1 292 ? -34.091 -14.474 -47.488  1.00 68.57  ? 291 SER A CB  1 
ATOM   2289  O OG  . SER A 1 292 ? -34.604 -15.533 -46.699  1.00 89.04  ? 291 SER A OG  1 
ATOM   2290  N N   . MET A 1 293 ? -34.676 -11.050 -48.183  1.00 67.28  ? 292 MET A N   1 
ATOM   2291  C CA  . MET A 1 293 ? -34.223 -10.014 -49.094  1.00 66.38  ? 292 MET A CA  1 
ATOM   2292  C C   . MET A 1 293 ? -33.204 -9.101  -48.414  1.00 80.49  ? 292 MET A C   1 
ATOM   2293  O O   . MET A 1 293 ? -33.263 -8.881  -47.202  1.00 72.82  ? 292 MET A O   1 
ATOM   2294  C CB  . MET A 1 293 ? -35.406 -9.189  -49.592  1.00 70.12  ? 292 MET A CB  1 
ATOM   2295  C CG  . MET A 1 293 ? -36.422 -9.971  -50.415  1.00 81.48  ? 292 MET A CG  1 
ATOM   2296  S SD  . MET A 1 293 ? -35.756 -10.592 -51.974  1.00 81.30  ? 292 MET A SD  1 
ATOM   2297  C CE  . MET A 1 293 ? -35.370 -12.287 -51.545  1.00 56.49  ? 292 MET A CE  1 
ATOM   2298  N N   . PRO A 1 294 ? -32.251 -8.560  -49.178  1.00 76.38  ? 293 PRO A N   1 
ATOM   2299  C CA  . PRO A 1 294 ? -31.256 -7.661  -48.576  1.00 72.17  ? 293 PRO A CA  1 
ATOM   2300  C C   . PRO A 1 294 ? -31.794 -6.278  -48.251  1.00 66.00  ? 293 PRO A C   1 
ATOM   2301  O O   . PRO A 1 294 ? -31.152 -5.558  -47.477  1.00 63.67  ? 293 PRO A O   1 
ATOM   2302  C CB  . PRO A 1 294 ? -30.156 -7.594  -49.643  1.00 70.01  ? 293 PRO A CB  1 
ATOM   2303  C CG  . PRO A 1 294 ? -30.878 -7.837  -50.925  1.00 75.92  ? 293 PRO A CG  1 
ATOM   2304  C CD  . PRO A 1 294 ? -31.983 -8.810  -50.606  1.00 68.99  ? 293 PRO A CD  1 
ATOM   2305  N N   . PHE A 1 295 ? -32.941 -5.883  -48.802  1.00 66.61  ? 294 PHE A N   1 
ATOM   2306  C CA  . PHE A 1 295 ? -33.457 -4.533  -48.629  1.00 63.23  ? 294 PHE A CA  1 
ATOM   2307  C C   . PHE A 1 295 ? -34.942 -4.567  -48.294  1.00 67.24  ? 294 PHE A C   1 
ATOM   2308  O O   . PHE A 1 295 ? -35.645 -5.541  -48.574  1.00 73.39  ? 294 PHE A O   1 
ATOM   2309  C CB  . PHE A 1 295 ? -33.237 -3.679  -49.884  1.00 56.73  ? 294 PHE A CB  1 
ATOM   2310  C CG  . PHE A 1 295 ? -31.810 -3.637  -50.344  1.00 73.04  ? 294 PHE A CG  1 
ATOM   2311  C CD1 . PHE A 1 295 ? -30.846 -2.987  -49.592  1.00 68.45  ? 294 PHE A CD1 1 
ATOM   2312  C CD2 . PHE A 1 295 ? -31.434 -4.240  -51.532  1.00 71.37  ? 294 PHE A CD2 1 
ATOM   2313  C CE1 . PHE A 1 295 ? -29.530 -2.944  -50.015  1.00 79.57  ? 294 PHE A CE1 1 
ATOM   2314  C CE2 . PHE A 1 295 ? -30.121 -4.199  -51.961  1.00 71.08  ? 294 PHE A CE2 1 
ATOM   2315  C CZ  . PHE A 1 295 ? -29.168 -3.552  -51.200  1.00 72.27  ? 294 PHE A CZ  1 
ATOM   2316  N N   . HIS A 1 296 ? -35.409 -3.476  -47.686  1.00 53.27  ? 295 HIS A N   1 
ATOM   2317  C CA  . HIS A 1 296 ? -36.823 -3.289  -47.394  1.00 56.06  ? 295 HIS A CA  1 
ATOM   2318  C C   . HIS A 1 296 ? -37.102 -1.795  -47.300  1.00 59.01  ? 295 HIS A C   1 
ATOM   2319  O O   . HIS A 1 296 ? -36.185 -0.974  -47.206  1.00 67.02  ? 295 HIS A O   1 
ATOM   2320  C CB  . HIS A 1 296 ? -37.238 -4.006  -46.104  1.00 63.76  ? 295 HIS A CB  1 
ATOM   2321  C CG  . HIS A 1 296 ? -36.977 -3.215  -44.862  1.00 61.95  ? 295 HIS A CG  1 
ATOM   2322  N ND1 . HIS A 1 296 ? -37.932 -2.414  -44.275  1.00 78.60  ? 295 HIS A ND1 1 
ATOM   2323  C CD2 . HIS A 1 296 ? -35.865 -3.095  -44.098  1.00 59.67  ? 295 HIS A CD2 1 
ATOM   2324  C CE1 . HIS A 1 296 ? -37.422 -1.838  -43.200  1.00 69.38  ? 295 HIS A CE1 1 
ATOM   2325  N NE2 . HIS A 1 296 ? -36.169 -2.234  -43.071  1.00 66.04  ? 295 HIS A NE2 1 
ATOM   2326  N N   . ASN A 1 297 ? -38.391 -1.445  -47.334  1.00 62.43  ? 296 ASN A N   1 
ATOM   2327  C CA  . ASN A 1 297 ? -38.812 -0.050  -47.263  1.00 54.49  ? 296 ASN A CA  1 
ATOM   2328  C C   . ASN A 1 297 ? -39.994 0.124   -46.318  1.00 56.83  ? 296 ASN A C   1 
ATOM   2329  O O   . ASN A 1 297 ? -40.816 1.030   -46.504  1.00 60.85  ? 296 ASN A O   1 
ATOM   2330  C CB  . ASN A 1 297 ? -39.170 0.489   -48.649  1.00 63.98  ? 296 ASN A CB  1 
ATOM   2331  C CG  . ASN A 1 297 ? -40.426 -0.154  -49.224  1.00 66.71  ? 296 ASN A CG  1 
ATOM   2332  O OD1 . ASN A 1 297 ? -40.784 -1.278  -48.869  1.00 62.95  ? 296 ASN A OD1 1 
ATOM   2333  N ND2 . ASN A 1 297 ? -41.100 0.562   -50.119  1.00 72.59  ? 296 ASN A ND2 1 
ATOM   2334  N N   . ILE A 1 298 ? -40.094 -0.729  -45.300  1.00 60.93  ? 297 ILE A N   1 
ATOM   2335  C CA  . ILE A 1 298 ? -41.302 -0.767  -44.484  1.00 63.30  ? 297 ILE A CA  1 
ATOM   2336  C C   . ILE A 1 298 ? -41.241 0.265   -43.365  1.00 58.17  ? 297 ILE A C   1 
ATOM   2337  O O   . ILE A 1 298 ? -42.141 1.101   -43.226  1.00 60.20  ? 297 ILE A O   1 
ATOM   2338  C CB  . ILE A 1 298 ? -41.525 -2.191  -43.944  1.00 68.91  ? 297 ILE A CB  1 
ATOM   2339  C CG1 . ILE A 1 298 ? -41.845 -3.136  -45.108  1.00 67.08  ? 297 ILE A CG1 1 
ATOM   2340  C CG2 . ILE A 1 298 ? -42.624 -2.199  -42.902  1.00 66.63  ? 297 ILE A CG2 1 
ATOM   2341  C CD1 . ILE A 1 298 ? -41.958 -4.588  -44.711  1.00 61.79  ? 297 ILE A CD1 1 
ATOM   2342  N N   . HIS A 1 299 ? -40.178 0.234   -42.558  1.00 70.84  ? 298 HIS A N   1 
ATOM   2343  C CA  . HIS A 1 299 ? -40.047 1.132   -41.415  1.00 63.55  ? 298 HIS A CA  1 
ATOM   2344  C C   . HIS A 1 299 ? -38.604 1.172   -40.907  1.00 64.17  ? 298 HIS A C   1 
ATOM   2345  O O   . HIS A 1 299 ? -37.918 0.141   -40.892  1.00 59.94  ? 298 HIS A O   1 
ATOM   2346  C CB  . HIS A 1 299 ? -40.999 0.695   -40.300  1.00 54.96  ? 298 HIS A CB  1 
ATOM   2347  C CG  . HIS A 1 299 ? -41.469 1.817   -39.430  1.00 69.82  ? 298 HIS A CG  1 
ATOM   2348  N ND1 . HIS A 1 299 ? -40.704 2.340   -38.409  1.00 63.89  ? 298 HIS A ND1 1 
ATOM   2349  C CD2 . HIS A 1 299 ? -42.630 2.513   -39.424  1.00 71.02  ? 298 HIS A CD2 1 
ATOM   2350  C CE1 . HIS A 1 299 ? -41.373 3.312   -37.815  1.00 57.91  ? 298 HIS A CE1 1 
ATOM   2351  N NE2 . HIS A 1 299 ? -42.545 3.436   -38.411  1.00 61.01  ? 298 HIS A NE2 1 
ATOM   2352  N N   . PRO A 1 300 ? -38.102 2.340   -40.492  1.00 65.97  ? 299 PRO A N   1 
ATOM   2353  C CA  . PRO A 1 300 ? -36.710 2.414   -40.015  1.00 60.64  ? 299 PRO A CA  1 
ATOM   2354  C C   . PRO A 1 300 ? -36.498 1.919   -38.592  1.00 66.27  ? 299 PRO A C   1 
ATOM   2355  O O   . PRO A 1 300 ? -35.363 1.562   -38.251  1.00 56.29  ? 299 PRO A O   1 
ATOM   2356  C CB  . PRO A 1 300 ? -36.388 3.913   -40.123  1.00 51.96  ? 299 PRO A CB  1 
ATOM   2357  C CG  . PRO A 1 300 ? -37.709 4.585   -39.962  1.00 53.11  ? 299 PRO A CG  1 
ATOM   2358  C CD  . PRO A 1 300 ? -38.721 3.672   -40.608  1.00 59.90  ? 299 PRO A CD  1 
ATOM   2359  N N   . LEU A 1 301 ? -37.537 1.874   -37.757  1.00 54.68  ? 300 LEU A N   1 
ATOM   2360  C CA  . LEU A 1 301 ? -37.371 1.569   -36.333  1.00 52.69  ? 300 LEU A CA  1 
ATOM   2361  C C   . LEU A 1 301 ? -37.553 0.069   -36.088  1.00 45.37  ? 300 LEU A C   1 
ATOM   2362  O O   . LEU A 1 301 ? -38.522 -0.388  -35.481  1.00 60.00  ? 300 LEU A O   1 
ATOM   2363  C CB  . LEU A 1 301 ? -38.346 2.391   -35.501  1.00 49.93  ? 300 LEU A CB  1 
ATOM   2364  C CG  . LEU A 1 301 ? -38.412 3.889   -35.811  1.00 57.51  ? 300 LEU A CG  1 
ATOM   2365  C CD1 . LEU A 1 301 ? -39.387 4.589   -34.876  1.00 48.38  ? 300 LEU A CD1 1 
ATOM   2366  C CD2 . LEU A 1 301 ? -37.032 4.522   -35.727  1.00 52.65  ? 300 LEU A CD2 1 
ATOM   2367  N N   . THR A 1 302 ? -36.574 -0.700  -36.554  1.00 61.15  ? 301 THR A N   1 
ATOM   2368  C CA  . THR A 1 302 ? -36.644 -2.155  -36.522  1.00 54.61  ? 301 THR A CA  1 
ATOM   2369  C C   . THR A 1 302 ? -35.863 -2.727  -35.343  1.00 53.12  ? 301 THR A C   1 
ATOM   2370  O O   . THR A 1 302 ? -34.847 -2.174  -34.914  1.00 53.00  ? 301 THR A O   1 
ATOM   2371  C CB  . THR A 1 302 ? -36.105 -2.754  -37.822  1.00 53.45  ? 301 THR A CB  1 
ATOM   2372  O OG1 . THR A 1 302 ? -34.722 -2.408  -37.971  1.00 59.88  ? 301 THR A OG1 1 
ATOM   2373  C CG2 . THR A 1 302 ? -36.883 -2.226  -39.014  1.00 63.54  ? 301 THR A CG2 1 
ATOM   2374  N N   . ILE A 1 303 ? -36.349 -3.855  -34.830  1.00 57.44  ? 302 ILE A N   1 
ATOM   2375  C CA  . ILE A 1 303 ? -35.664 -4.626  -33.798  1.00 55.93  ? 302 ILE A CA  1 
ATOM   2376  C C   . ILE A 1 303 ? -35.471 -6.040  -34.326  1.00 62.73  ? 302 ILE A C   1 
ATOM   2377  O O   . ILE A 1 303 ? -36.451 -6.744  -34.600  1.00 73.28  ? 302 ILE A O   1 
ATOM   2378  C CB  . ILE A 1 303 ? -36.447 -4.643  -32.475  1.00 50.12  ? 302 ILE A CB  1 
ATOM   2379  C CG1 . ILE A 1 303 ? -36.712 -3.222  -31.981  1.00 57.31  ? 302 ILE A CG1 1 
ATOM   2380  C CG2 . ILE A 1 303 ? -35.689 -5.428  -31.420  1.00 51.52  ? 302 ILE A CG2 1 
ATOM   2381  C CD1 . ILE A 1 303 ? -37.528 -3.171  -30.705  1.00 61.87  ? 302 ILE A CD1 1 
ATOM   2382  N N   . GLY A 1 304 ? -34.213 -6.457  -34.468  1.00 60.91  ? 303 GLY A N   1 
ATOM   2383  C CA  . GLY A 1 304 ? -33.868 -7.801  -34.873  1.00 53.74  ? 303 GLY A CA  1 
ATOM   2384  C C   . GLY A 1 304 ? -32.904 -7.797  -36.036  1.00 66.53  ? 303 GLY A C   1 
ATOM   2385  O O   . GLY A 1 304 ? -32.284 -6.779  -36.364  1.00 70.07  ? 303 GLY A O   1 
ATOM   2386  N N   . GLU A 1 305 ? -32.766 -8.963  -36.667  1.00 55.66  ? 304 GLU A N   1 
ATOM   2387  C CA  . GLU A 1 305 ? -31.968 -9.115  -37.880  1.00 61.62  ? 304 GLU A CA  1 
ATOM   2388  C C   . GLU A 1 305 ? -32.863 -8.795  -39.071  1.00 70.60  ? 304 GLU A C   1 
ATOM   2389  O O   . GLU A 1 305 ? -33.729 -9.597  -39.438  1.00 66.77  ? 304 GLU A O   1 
ATOM   2390  C CB  . GLU A 1 305 ? -31.394 -10.526 -37.979  1.00 70.50  ? 304 GLU A CB  1 
ATOM   2391  C CG  . GLU A 1 305 ? -30.337 -10.846 -36.935  1.00 65.59  ? 304 GLU A CG  1 
ATOM   2392  C CD  . GLU A 1 305 ? -30.532 -12.211 -36.306  1.00 75.10  ? 304 GLU A CD  1 
ATOM   2393  O OE1 . GLU A 1 305 ? -31.648 -12.487 -35.815  1.00 68.27  ? 304 GLU A OE1 1 
ATOM   2394  O OE2 . GLU A 1 305 ? -29.573 -13.011 -36.308  1.00 89.19  ? 304 GLU A OE2 1 
ATOM   2395  N N   . CYS A 1 306 ? -32.653 -7.635  -39.674  1.00 63.39  ? 305 CYS A N   1 
ATOM   2396  C CA  . CYS A 1 306 ? -33.559 -7.077  -40.663  1.00 62.43  ? 305 CYS A CA  1 
ATOM   2397  C C   . CYS A 1 306 ? -32.804 -6.690  -41.922  1.00 64.10  ? 305 CYS A C   1 
ATOM   2398  O O   . CYS A 1 306 ? -31.590 -6.461  -41.885  1.00 60.56  ? 305 CYS A O   1 
ATOM   2399  C CB  . CYS A 1 306 ? -34.282 -5.845  -40.099  1.00 67.67  ? 305 CYS A CB  1 
ATOM   2400  S SG  . CYS A 1 306 ? -35.309 -6.162  -38.643  1.00 85.01  ? 305 CYS A SG  1 
ATOM   2401  N N   . PRO A 1 307 ? -33.493 -6.620  -43.059  1.00 64.00  ? 306 PRO A N   1 
ATOM   2402  C CA  . PRO A 1 307 ? -32.864 -6.091  -44.272  1.00 65.02  ? 306 PRO A CA  1 
ATOM   2403  C C   . PRO A 1 307 ? -32.557 -4.609  -44.122  1.00 64.61  ? 306 PRO A C   1 
ATOM   2404  O O   . PRO A 1 307 ? -33.132 -3.905  -43.291  1.00 60.73  ? 306 PRO A O   1 
ATOM   2405  C CB  . PRO A 1 307 ? -33.918 -6.329  -45.359  1.00 69.24  ? 306 PRO A CB  1 
ATOM   2406  C CG  . PRO A 1 307 ? -34.833 -7.371  -44.794  1.00 72.51  ? 306 PRO A CG  1 
ATOM   2407  C CD  . PRO A 1 307 ? -34.850 -7.128  -43.321  1.00 60.09  ? 306 PRO A CD  1 
ATOM   2408  N N   . LYS A 1 308 ? -31.620 -4.140  -44.941  1.00 56.69  ? 307 LYS A N   1 
ATOM   2409  C CA  . LYS A 1 308 ? -31.234 -2.737  -44.890  1.00 51.86  ? 307 LYS A CA  1 
ATOM   2410  C C   . LYS A 1 308 ? -32.360 -1.856  -45.420  1.00 65.21  ? 307 LYS A C   1 
ATOM   2411  O O   . LYS A 1 308 ? -32.915 -2.112  -46.493  1.00 56.65  ? 307 LYS A O   1 
ATOM   2412  C CB  . LYS A 1 308 ? -29.949 -2.513  -45.681  1.00 51.77  ? 307 LYS A CB  1 
ATOM   2413  C CG  . LYS A 1 308 ? -28.753 -3.256  -45.105  1.00 56.99  ? 307 LYS A CG  1 
ATOM   2414  C CD  . LYS A 1 308 ? -28.570 -2.964  -43.622  1.00 52.40  ? 307 LYS A CD  1 
ATOM   2415  C CE  . LYS A 1 308 ? -27.362 -3.697  -43.057  1.00 56.99  ? 307 LYS A CE  1 
ATOM   2416  N NZ  . LYS A 1 308 ? -27.527 -5.177  -43.100  1.00 63.68  ? 307 LYS A NZ  1 
ATOM   2417  N N   . TYR A 1 309 ? -32.687 -0.812  -44.663  1.00 57.76  ? 308 TYR A N   1 
ATOM   2418  C CA  . TYR A 1 309 ? -33.808 0.062   -44.984  1.00 56.53  ? 308 TYR A CA  1 
ATOM   2419  C C   . TYR A 1 309 ? -33.400 1.084   -46.040  1.00 58.35  ? 308 TYR A C   1 
ATOM   2420  O O   . TYR A 1 309 ? -32.424 1.818   -45.860  1.00 60.04  ? 308 TYR A O   1 
ATOM   2421  C CB  . TYR A 1 309 ? -34.292 0.759   -43.712  1.00 46.98  ? 308 TYR A CB  1 
ATOM   2422  C CG  . TYR A 1 309 ? -35.397 1.773   -43.904  1.00 58.75  ? 308 TYR A CG  1 
ATOM   2423  C CD1 . TYR A 1 309 ? -36.676 1.379   -44.277  1.00 60.28  ? 308 TYR A CD1 1 
ATOM   2424  C CD2 . TYR A 1 309 ? -35.168 3.123   -43.678  1.00 60.69  ? 308 TYR A CD2 1 
ATOM   2425  C CE1 . TYR A 1 309 ? -37.690 2.306   -44.441  1.00 54.48  ? 308 TYR A CE1 1 
ATOM   2426  C CE2 . TYR A 1 309 ? -36.174 4.057   -43.839  1.00 56.97  ? 308 TYR A CE2 1 
ATOM   2427  C CZ  . TYR A 1 309 ? -37.432 3.643   -44.219  1.00 57.74  ? 308 TYR A CZ  1 
ATOM   2428  O OH  . TYR A 1 309 ? -38.436 4.571   -44.378  1.00 61.22  ? 308 TYR A OH  1 
ATOM   2429  N N   . VAL A 1 310 ? -34.149 1.128   -47.145  1.00 62.30  ? 309 VAL A N   1 
ATOM   2430  C CA  . VAL A 1 310 ? -33.843 2.009   -48.264  1.00 61.63  ? 309 VAL A CA  1 
ATOM   2431  C C   . VAL A 1 310 ? -35.089 2.797   -48.649  1.00 56.24  ? 309 VAL A C   1 
ATOM   2432  O O   . VAL A 1 310 ? -36.218 2.431   -48.315  1.00 60.86  ? 309 VAL A O   1 
ATOM   2433  C CB  . VAL A 1 310 ? -33.304 1.241   -49.489  1.00 57.03  ? 309 VAL A CB  1 
ATOM   2434  C CG1 . VAL A 1 310 ? -32.002 0.538   -49.148  1.00 57.90  ? 309 VAL A CG1 1 
ATOM   2435  C CG2 . VAL A 1 310 ? -34.336 0.247   -49.986  1.00 59.09  ? 309 VAL A CG2 1 
ATOM   2436  N N   . LYS A 1 311 ? -34.861 3.901   -49.360  1.00 64.96  ? 310 LYS A N   1 
ATOM   2437  C CA  . LYS A 1 311 ? -35.943 4.725   -49.897  1.00 72.65  ? 310 LYS A CA  1 
ATOM   2438  C C   . LYS A 1 311 ? -36.190 4.349   -51.358  1.00 81.44  ? 310 LYS A C   1 
ATOM   2439  O O   . LYS A 1 311 ? -35.870 5.082   -52.293  1.00 91.49  ? 310 LYS A O   1 
ATOM   2440  C CB  . LYS A 1 311 ? -35.609 6.207   -49.743  1.00 71.63  ? 310 LYS A CB  1 
ATOM   2441  C CG  . LYS A 1 311 ? -36.771 7.151   -50.035  1.00 72.45  ? 310 LYS A CG  1 
ATOM   2442  C CD  . LYS A 1 311 ? -36.418 8.581   -49.644  1.00 81.24  ? 310 LYS A CD  1 
ATOM   2443  C CE  . LYS A 1 311 ? -37.661 9.440   -49.444  1.00 77.25  ? 310 LYS A CE  1 
ATOM   2444  N NZ  . LYS A 1 311 ? -38.303 9.837   -50.727  1.00 93.59  ? 310 LYS A NZ  1 
ATOM   2445  N N   . SER A 1 312 ? -36.764 3.163   -51.536  1.00 73.32  ? 311 SER A N   1 
ATOM   2446  C CA  . SER A 1 312 ? -37.090 2.652   -52.858  1.00 77.77  ? 311 SER A CA  1 
ATOM   2447  C C   . SER A 1 312 ? -38.477 2.032   -52.832  1.00 81.19  ? 311 SER A C   1 
ATOM   2448  O O   . SER A 1 312 ? -38.908 1.477   -51.818  1.00 88.25  ? 311 SER A O   1 
ATOM   2449  C CB  . SER A 1 312 ? -36.067 1.610   -53.334  1.00 78.61  ? 311 SER A CB  1 
ATOM   2450  O OG  . SER A 1 312 ? -34.778 2.181   -53.468  1.00 89.21  ? 311 SER A OG  1 
ATOM   2451  N N   . ASN A 1 313 ? -39.177 2.144   -53.959  1.00 86.78  ? 312 ASN A N   1 
ATOM   2452  C CA  . ASN A 1 313 ? -40.431 1.432   -54.162  1.00 87.70  ? 312 ASN A CA  1 
ATOM   2453  C C   . ASN A 1 313 ? -40.249 0.118   -54.904  1.00 84.13  ? 312 ASN A C   1 
ATOM   2454  O O   . ASN A 1 313 ? -41.048 -0.804  -54.714  1.00 87.15  ? 312 ASN A O   1 
ATOM   2455  C CB  . ASN A 1 313 ? -41.426 2.308   -54.929  1.00 86.71  ? 312 ASN A CB  1 
ATOM   2456  C CG  . ASN A 1 313 ? -42.065 3.368   -54.054  1.00 98.81  ? 312 ASN A CG  1 
ATOM   2457  O OD1 . ASN A 1 313 ? -42.378 3.121   -52.889  1.00 98.57  ? 312 ASN A OD1 1 
ATOM   2458  N ND2 . ASN A 1 313 ? -42.264 4.556   -54.613  1.00 98.66  ? 312 ASN A ND2 1 
ATOM   2459  N N   . LYS A 1 314 ? -39.211 0.011   -55.733  1.00 86.46  ? 313 LYS A N   1 
ATOM   2460  C CA  . LYS A 1 314 ? -38.941 -1.196  -56.499  1.00 82.45  ? 313 LYS A CA  1 
ATOM   2461  C C   . LYS A 1 314 ? -37.439 -1.359  -56.673  1.00 68.88  ? 313 LYS A C   1 
ATOM   2462  O O   . LYS A 1 314 ? -36.729 -0.387  -56.945  1.00 66.49  ? 313 LYS A O   1 
ATOM   2463  C CB  . LYS A 1 314 ? -39.614 -1.149  -57.877  1.00 86.98  ? 313 LYS A CB  1 
ATOM   2464  C CG  . LYS A 1 314 ? -41.114 -1.380  -57.869  1.00 100.11 ? 313 LYS A CG  1 
ATOM   2465  C CD  . LYS A 1 314 ? -41.699 -1.178  -59.258  1.00 106.87 ? 313 LYS A CD  1 
ATOM   2466  C CE  . LYS A 1 314 ? -43.064 -1.830  -59.382  1.00 104.35 ? 313 LYS A CE  1 
ATOM   2467  N NZ  . LYS A 1 314 ? -42.977 -3.307  -59.206  1.00 96.08  ? 313 LYS A NZ  1 
ATOM   2468  N N   . LEU A 1 315 ? -36.960 -2.594  -56.504  1.00 64.53  ? 314 LEU A N   1 
ATOM   2469  C CA  . LEU A 1 315 ? -35.602 -2.984  -56.895  1.00 75.70  ? 314 LEU A CA  1 
ATOM   2470  C C   . LEU A 1 315 ? -35.736 -4.285  -57.682  1.00 74.81  ? 314 LEU A C   1 
ATOM   2471  O O   . LEU A 1 315 ? -35.557 -5.376  -57.137  1.00 77.40  ? 314 LEU A O   1 
ATOM   2472  C CB  . LEU A 1 315 ? -34.690 -3.140  -55.679  1.00 71.49  ? 314 LEU A CB  1 
ATOM   2473  C CG  . LEU A 1 315 ? -34.341 -1.870  -54.903  1.00 73.65  ? 314 LEU A CG  1 
ATOM   2474  C CD1 . LEU A 1 315 ? -33.483 -2.211  -53.696  1.00 69.13  ? 314 LEU A CD1 1 
ATOM   2475  C CD2 . LEU A 1 315 ? -33.631 -0.871  -55.803  1.00 68.88  ? 314 LEU A CD2 1 
ATOM   2476  N N   . VAL A 1 316 ? -36.026 -4.166  -58.973  1.00 73.96  ? 315 VAL A N   1 
ATOM   2477  C CA  . VAL A 1 316 ? -36.345 -5.318  -59.808  1.00 78.21  ? 315 VAL A CA  1 
ATOM   2478  C C   . VAL A 1 316 ? -35.127 -5.656  -60.659  1.00 69.38  ? 315 VAL A C   1 
ATOM   2479  O O   . VAL A 1 316 ? -34.610 -4.808  -61.398  1.00 69.79  ? 315 VAL A O   1 
ATOM   2480  C CB  . VAL A 1 316 ? -37.595 -5.063  -60.668  1.00 77.02  ? 315 VAL A CB  1 
ATOM   2481  C CG1 . VAL A 1 316 ? -37.463 -3.781  -61.487  1.00 84.00  ? 315 VAL A CG1 1 
ATOM   2482  C CG2 . VAL A 1 316 ? -37.881 -6.260  -61.558  1.00 71.99  ? 315 VAL A CG2 1 
ATOM   2483  N N   . LEU A 1 317 ? -34.655 -6.892  -60.534  1.00 65.71  ? 316 LEU A N   1 
ATOM   2484  C CA  . LEU A 1 317 ? -33.500 -7.377  -61.275  1.00 83.72  ? 316 LEU A CA  1 
ATOM   2485  C C   . LEU A 1 317 ? -33.965 -8.146  -62.503  1.00 84.76  ? 316 LEU A C   1 
ATOM   2486  O O   . LEU A 1 317 ? -34.855 -8.998  -62.409  1.00 82.30  ? 316 LEU A O   1 
ATOM   2487  C CB  . LEU A 1 317 ? -32.624 -8.275  -60.402  1.00 65.75  ? 316 LEU A CB  1 
ATOM   2488  C CG  . LEU A 1 317 ? -31.588 -7.603  -59.506  1.00 72.34  ? 316 LEU A CG  1 
ATOM   2489  C CD1 . LEU A 1 317 ? -30.911 -8.645  -58.634  1.00 63.36  ? 316 LEU A CD1 1 
ATOM   2490  C CD2 . LEU A 1 317 ? -30.566 -6.857  -60.349  1.00 70.69  ? 316 LEU A CD2 1 
ATOM   2491  N N   . ALA A 1 318 ? -33.360 -7.845  -63.648  1.00 74.41  ? 317 ALA A N   1 
ATOM   2492  C CA  . ALA A 1 318 ? -33.647 -8.600  -64.857  1.00 78.61  ? 317 ALA A CA  1 
ATOM   2493  C C   . ALA A 1 318 ? -32.976 -9.964  -64.782  1.00 76.77  ? 317 ALA A C   1 
ATOM   2494  O O   . ALA A 1 318 ? -31.776 -10.065 -64.512  1.00 78.29  ? 317 ALA A O   1 
ATOM   2495  C CB  . ALA A 1 318 ? -33.165 -7.839  -66.091  1.00 79.01  ? 317 ALA A CB  1 
ATOM   2496  N N   . THR A 1 319 ? -33.757 -11.012 -65.004  1.00 75.89  ? 318 THR A N   1 
ATOM   2497  C CA  . THR A 1 319 ? -33.236 -12.369 -65.089  1.00 81.81  ? 318 THR A CA  1 
ATOM   2498  C C   . THR A 1 319 ? -33.414 -12.982 -66.467  1.00 94.21  ? 318 THR A C   1 
ATOM   2499  O O   . THR A 1 319 ? -32.510 -13.666 -66.954  1.00 97.30  ? 318 THR A O   1 
ATOM   2500  C CB  . THR A 1 319 ? -33.908 -13.265 -64.039  1.00 77.72  ? 318 THR A CB  1 
ATOM   2501  O OG1 . THR A 1 319 ? -35.331 -13.126 -64.128  1.00 78.55  ? 318 THR A OG1 1 
ATOM   2502  C CG2 . THR A 1 319 ? -33.452 -12.878 -62.641  1.00 87.49  ? 318 THR A CG2 1 
ATOM   2503  N N   . GLY A 1 320 ? -34.552 -12.742 -67.117  1.00 83.28  ? 319 GLY A N   1 
ATOM   2504  C CA  . GLY A 1 320 ? -34.803 -13.244 -68.449  1.00 86.21  ? 319 GLY A CA  1 
ATOM   2505  C C   . GLY A 1 320 ? -34.259 -12.322 -69.525  1.00 84.76  ? 319 GLY A C   1 
ATOM   2506  O O   . GLY A 1 320 ? -33.568 -11.337 -69.259  1.00 74.32  ? 319 GLY A O   1 
ATOM   2507  N N   . LEU A 1 321 ? -34.591 -12.658 -70.767  1.00 90.62  ? 320 LEU A N   1 
ATOM   2508  C CA  . LEU A 1 321 ? -34.097 -11.932 -71.926  1.00 86.29  ? 320 LEU A CA  1 
ATOM   2509  C C   . LEU A 1 321 ? -34.991 -10.737 -72.244  1.00 75.49  ? 320 LEU A C   1 
ATOM   2510  O O   . LEU A 1 321 ? -36.081 -10.574 -71.693  1.00 83.29  ? 320 LEU A O   1 
ATOM   2511  C CB  . LEU A 1 321 ? -34.014 -12.852 -73.144  1.00 84.50  ? 320 LEU A CB  1 
ATOM   2512  C CG  . LEU A 1 321 ? -33.473 -14.267 -72.941  1.00 85.12  ? 320 LEU A CG  1 
ATOM   2513  C CD1 . LEU A 1 321 ? -34.612 -15.255 -72.733  1.00 90.98  ? 320 LEU A CD1 1 
ATOM   2514  C CD2 . LEU A 1 321 ? -32.622 -14.667 -74.128  1.00 93.07  ? 320 LEU A CD2 1 
ATOM   2515  N N   . ARG A 1 322 ? -34.505 -9.889  -73.149  1.00 75.05  ? 321 ARG A N   1 
ATOM   2516  C CA  . ARG A 1 322 ? -35.336 -8.822  -73.687  1.00 87.19  ? 321 ARG A CA  1 
ATOM   2517  C C   . ARG A 1 322 ? -36.546 -9.412  -74.399  1.00 93.99  ? 321 ARG A C   1 
ATOM   2518  O O   . ARG A 1 322 ? -36.432 -10.380 -75.156  1.00 98.81  ? 321 ARG A O   1 
ATOM   2519  C CB  . ARG A 1 322 ? -34.530 -7.955  -74.654  1.00 80.96  ? 321 ARG A CB  1 
ATOM   2520  C CG  . ARG A 1 322 ? -33.594 -6.963  -73.987  1.00 87.80  ? 321 ARG A CG  1 
ATOM   2521  C CD  . ARG A 1 322 ? -32.807 -6.180  -75.027  1.00 87.91  ? 321 ARG A CD  1 
ATOM   2522  N NE  . ARG A 1 322 ? -32.154 -5.008  -74.456  1.00 91.15  ? 321 ARG A NE  1 
ATOM   2523  C CZ  . ARG A 1 322 ? -32.690 -3.796  -74.420  1.00 92.88  ? 321 ARG A CZ  1 
ATOM   2524  N NH1 . ARG A 1 322 ? -33.895 -3.558  -74.915  1.00 85.01  ? 321 ARG A NH1 1 
ATOM   2525  N NH2 . ARG A 1 322 ? -32.001 -2.797  -73.875  1.00 86.92  ? 321 ARG A NH2 1 
ATOM   2526  N N   . ASN A 1 323 ? -37.714 -8.827  -74.147  1.00 83.62  ? 322 ASN A N   1 
ATOM   2527  C CA  . ASN A 1 323 ? -38.969 -9.308  -74.704  1.00 88.16  ? 322 ASN A CA  1 
ATOM   2528  C C   . ASN A 1 323 ? -39.589 -8.223  -75.571  1.00 104.04 ? 322 ASN A C   1 
ATOM   2529  O O   . ASN A 1 323 ? -39.654 -7.058  -75.163  1.00 109.70 ? 322 ASN A O   1 
ATOM   2530  C CB  . ASN A 1 323 ? -39.945 -9.715  -73.599  1.00 86.97  ? 322 ASN A CB  1 
ATOM   2531  C CG  . ASN A 1 323 ? -41.190 -10.381 -74.145  1.00 91.19  ? 322 ASN A CG  1 
ATOM   2532  O OD1 . ASN A 1 323 ? -41.109 -11.270 -74.992  1.00 95.10  ? 322 ASN A OD1 1 
ATOM   2533  N ND2 . ASN A 1 323 ? -42.351 -9.941  -73.678  1.00 88.98  ? 322 ASN A ND2 1 
ATOM   2534  N N   . SER A 1 324 ? -40.046 -8.607  -76.760  1.00 104.85 ? 323 SER A N   1 
ATOM   2535  C CA  . SER A 1 324 ? -40.690 -7.681  -77.674  1.00 123.63 ? 323 SER A CA  1 
ATOM   2536  C C   . SER A 1 324 ? -42.036 -8.244  -78.111  1.00 125.00 ? 323 SER A C   1 
ATOM   2537  O O   . SER A 1 324 ? -42.171 -9.460  -78.296  1.00 127.54 ? 323 SER A O   1 
ATOM   2538  C CB  . SER A 1 324 ? -39.807 -7.419  -78.903  1.00 116.60 ? 323 SER A CB  1 
ATOM   2539  O OG  . SER A 1 324 ? -40.360 -6.407  -79.727  1.00 103.34 ? 323 SER A OG  1 
ATOM   2540  N N   . PRO A 1 325 ? -43.055 -7.387  -78.281  1.00 128.67 ? 324 PRO A N   1 
ATOM   2541  C CA  . PRO A 1 325 ? -44.383 -7.839  -78.711  1.00 129.28 ? 324 PRO A CA  1 
ATOM   2542  C C   . PRO A 1 325 ? -44.417 -8.248  -80.180  1.00 121.79 ? 324 PRO A C   1 
ATOM   2543  O O   . PRO A 1 325 ? -45.050 -9.254  -80.503  1.00 120.48 ? 324 PRO A O   1 
ATOM   2544  C CB  . PRO A 1 325 ? -45.264 -6.612  -78.466  1.00 123.18 ? 324 PRO A CB  1 
ATOM   2545  C CG  . PRO A 1 325 ? -44.330 -5.458  -78.578  1.00 125.73 ? 324 PRO A CG  1 
ATOM   2546  C CD  . PRO A 1 325 ? -43.026 -5.939  -78.008  1.00 127.81 ? 324 PRO A CD  1 
ATOM   2547  N N   . GLY B 2 1   ? -27.523 -2.776  -78.994  1.00 107.09 ? 1   GLY B N   1 
ATOM   2548  C CA  . GLY B 2 1   ? -26.913 -3.768  -78.126  1.00 124.07 ? 1   GLY B CA  1 
ATOM   2549  C C   . GLY B 2 1   ? -25.402 -3.811  -78.242  1.00 138.51 ? 1   GLY B C   1 
ATOM   2550  O O   . GLY B 2 1   ? -24.844 -3.453  -79.280  1.00 142.34 ? 1   GLY B O   1 
ATOM   2551  N N   . LEU B 2 2   ? -24.737 -4.245  -77.168  1.00 137.92 ? 2   LEU B N   1 
ATOM   2552  C CA  . LEU B 2 2   ? -23.280 -4.333  -77.185  1.00 139.93 ? 2   LEU B CA  1 
ATOM   2553  C C   . LEU B 2 2   ? -22.801 -5.329  -78.233  1.00 138.05 ? 2   LEU B C   1 
ATOM   2554  O O   . LEU B 2 2   ? -21.940 -5.012  -79.063  1.00 133.38 ? 2   LEU B O   1 
ATOM   2555  C CB  . LEU B 2 2   ? -22.752 -4.725  -75.804  1.00 132.85 ? 2   LEU B CB  1 
ATOM   2556  C CG  . LEU B 2 2   ? -22.382 -3.622  -74.811  1.00 125.75 ? 2   LEU B CG  1 
ATOM   2557  C CD1 . LEU B 2 2   ? -21.423 -4.168  -73.761  1.00 115.93 ? 2   LEU B CD1 1 
ATOM   2558  C CD2 . LEU B 2 2   ? -21.779 -2.418  -75.516  1.00 108.36 ? 2   LEU B CD2 1 
ATOM   2559  N N   . PHE B 2 3   ? -23.348 -6.539  -78.213  1.00 141.01 ? 3   PHE B N   1 
ATOM   2560  C CA  . PHE B 2 3   ? -22.910 -7.595  -79.113  1.00 141.44 ? 3   PHE B CA  1 
ATOM   2561  C C   . PHE B 2 3   ? -23.737 -7.667  -80.390  1.00 137.14 ? 3   PHE B C   1 
ATOM   2562  O O   . PHE B 2 3   ? -23.454 -8.513  -81.245  1.00 139.93 ? 3   PHE B O   1 
ATOM   2563  C CB  . PHE B 2 3   ? -22.937 -8.942  -78.384  1.00 127.79 ? 3   PHE B CB  1 
ATOM   2564  C CG  . PHE B 2 3   ? -22.071 -8.976  -77.154  1.00 132.72 ? 3   PHE B CG  1 
ATOM   2565  C CD1 . PHE B 2 3   ? -22.581 -8.605  -75.919  1.00 124.16 ? 3   PHE B CD1 1 
ATOM   2566  C CD2 . PHE B 2 3   ? -20.744 -9.364  -77.235  1.00 133.76 ? 3   PHE B CD2 1 
ATOM   2567  C CE1 . PHE B 2 3   ? -21.786 -8.628  -74.789  1.00 124.33 ? 3   PHE B CE1 1 
ATOM   2568  C CE2 . PHE B 2 3   ? -19.944 -9.390  -76.108  1.00 137.00 ? 3   PHE B CE2 1 
ATOM   2569  C CZ  . PHE B 2 3   ? -20.466 -9.022  -74.883  1.00 132.65 ? 3   PHE B CZ  1 
ATOM   2570  N N   . GLY B 2 4   ? -24.736 -6.798  -80.542  1.00 138.38 ? 4   GLY B N   1 
ATOM   2571  C CA  . GLY B 2 4   ? -25.514 -6.722  -81.761  1.00 141.57 ? 4   GLY B CA  1 
ATOM   2572  C C   . GLY B 2 4   ? -26.187 -8.026  -82.131  1.00 139.69 ? 4   GLY B C   1 
ATOM   2573  O O   . GLY B 2 4   ? -26.131 -8.456  -83.288  1.00 134.43 ? 4   GLY B O   1 
ATOM   2574  N N   . ALA B 2 5   ? -26.816 -8.676  -81.153  1.00 133.91 ? 5   ALA B N   1 
ATOM   2575  C CA  . ALA B 2 5   ? -27.472 -9.957  -81.385  1.00 127.15 ? 5   ALA B CA  1 
ATOM   2576  C C   . ALA B 2 5   ? -28.980 -9.874  -81.193  1.00 129.80 ? 5   ALA B C   1 
ATOM   2577  O O   . ALA B 2 5   ? -29.726 -10.190 -82.123  1.00 132.40 ? 5   ALA B O   1 
ATOM   2578  C CB  . ALA B 2 5   ? -26.865 -11.026 -80.470  1.00 112.12 ? 5   ALA B CB  1 
ATOM   2579  N N   . ILE B 2 6   ? -29.455 -9.444  -80.022  1.00 122.99 ? 6   ILE B N   1 
ATOM   2580  C CA  . ILE B 2 6   ? -30.894 -9.407  -79.774  1.00 124.91 ? 6   ILE B CA  1 
ATOM   2581  C C   . ILE B 2 6   ? -31.574 -8.391  -80.685  1.00 129.03 ? 6   ILE B C   1 
ATOM   2582  O O   . ILE B 2 6   ? -32.643 -8.659  -81.248  1.00 123.21 ? 6   ILE B O   1 
ATOM   2583  C CB  . ILE B 2 6   ? -31.174 -9.124  -78.286  1.00 125.37 ? 6   ILE B CB  1 
ATOM   2584  C CG1 . ILE B 2 6   ? -30.963 -10.395 -77.459  1.00 117.40 ? 6   ILE B CG1 1 
ATOM   2585  C CG2 . ILE B 2 6   ? -32.583 -8.578  -78.089  1.00 111.48 ? 6   ILE B CG2 1 
ATOM   2586  C CD1 . ILE B 2 6   ? -31.425 -10.279 -76.021  1.00 111.88 ? 6   ILE B CD1 1 
ATOM   2587  N N   . ALA B 2 7   ? -30.974 -7.209  -80.841  1.00 132.36 ? 7   ALA B N   1 
ATOM   2588  C CA  . ALA B 2 7   ? -31.475 -6.190  -81.757  1.00 123.19 ? 7   ALA B CA  1 
ATOM   2589  C C   . ALA B 2 7   ? -30.489 -5.905  -82.883  1.00 132.31 ? 7   ALA B C   1 
ATOM   2590  O O   . ALA B 2 7   ? -30.617 -4.891  -83.576  1.00 138.30 ? 7   ALA B O   1 
ATOM   2591  C CB  . ALA B 2 7   ? -31.807 -4.901  -81.001  1.00 121.64 ? 7   ALA B CB  1 
ATOM   2592  N N   . GLY B 2 8   ? -29.505 -6.778  -83.079  1.00 133.37 ? 8   GLY B N   1 
ATOM   2593  C CA  . GLY B 2 8   ? -28.521 -6.577  -84.123  1.00 129.57 ? 8   GLY B CA  1 
ATOM   2594  C C   . GLY B 2 8   ? -28.870 -7.337  -85.383  1.00 136.97 ? 8   GLY B C   1 
ATOM   2595  O O   . GLY B 2 8   ? -29.783 -6.941  -86.114  1.00 134.48 ? 8   GLY B O   1 
ATOM   2596  N N   . PHE B 2 9   ? -28.159 -8.428  -85.661  1.00 134.51 ? 9   PHE B N   1 
ATOM   2597  C CA  . PHE B 2 9   ? -28.530 -9.229  -86.818  1.00 127.78 ? 9   PHE B CA  1 
ATOM   2598  C C   . PHE B 2 9   ? -29.758 -10.093 -86.568  1.00 127.57 ? 9   PHE B C   1 
ATOM   2599  O O   . PHE B 2 9   ? -30.405 -10.489 -87.537  1.00 128.51 ? 9   PHE B O   1 
ATOM   2600  C CB  . PHE B 2 9   ? -27.350 -10.087 -87.291  1.00 124.82 ? 9   PHE B CB  1 
ATOM   2601  C CG  . PHE B 2 9   ? -26.970 -11.196 -86.355  1.00 133.01 ? 9   PHE B CG  1 
ATOM   2602  C CD1 . PHE B 2 9   ? -26.212 -10.938 -85.227  1.00 131.26 ? 9   PHE B CD1 1 
ATOM   2603  C CD2 . PHE B 2 9   ? -27.336 -12.504 -86.627  1.00 125.81 ? 9   PHE B CD2 1 
ATOM   2604  C CE1 . PHE B 2 9   ? -25.848 -11.955 -84.372  1.00 122.48 ? 9   PHE B CE1 1 
ATOM   2605  C CE2 . PHE B 2 9   ? -26.972 -13.526 -85.776  1.00 128.79 ? 9   PHE B CE2 1 
ATOM   2606  C CZ  . PHE B 2 9   ? -26.224 -13.252 -84.647  1.00 123.78 ? 9   PHE B CZ  1 
ATOM   2607  N N   . ILE B 2 10  ? -30.112 -10.377 -85.310  1.00 123.73 ? 10  ILE B N   1 
ATOM   2608  C CA  . ILE B 2 10  ? -31.446 -10.879 -84.991  1.00 121.17 ? 10  ILE B CA  1 
ATOM   2609  C C   . ILE B 2 10  ? -32.296 -9.702  -84.544  1.00 127.10 ? 10  ILE B C   1 
ATOM   2610  O O   . ILE B 2 10  ? -31.824 -8.806  -83.834  1.00 135.42 ? 10  ILE B O   1 
ATOM   2611  C CB  . ILE B 2 10  ? -31.413 -11.983 -83.916  1.00 121.51 ? 10  ILE B CB  1 
ATOM   2612  C CG1 . ILE B 2 10  ? -30.473 -13.099 -84.334  1.00 111.44 ? 10  ILE B CG1 1 
ATOM   2613  C CG2 . ILE B 2 10  ? -32.810 -12.568 -83.697  1.00 113.48 ? 10  ILE B CG2 1 
ATOM   2614  C CD1 . ILE B 2 10  ? -29.351 -13.283 -83.389  1.00 100.96 ? 10  ILE B CD1 1 
ATOM   2615  N N   . GLU B 2 11  ? -33.559 -9.696  -84.975  1.00 121.79 ? 11  GLU B N   1 
ATOM   2616  C CA  . GLU B 2 11  ? -34.411 -8.525  -84.808  1.00 128.40 ? 11  GLU B CA  1 
ATOM   2617  C C   . GLU B 2 11  ? -35.805 -8.883  -84.305  1.00 126.96 ? 11  GLU B C   1 
ATOM   2618  O O   . GLU B 2 11  ? -36.733 -8.083  -84.468  1.00 127.75 ? 11  GLU B O   1 
ATOM   2619  C CB  . GLU B 2 11  ? -34.521 -7.741  -86.134  1.00 127.82 ? 11  GLU B CB  1 
ATOM   2620  C CG  . GLU B 2 11  ? -34.898 -8.562  -87.385  1.00 126.63 ? 11  GLU B CG  1 
ATOM   2621  C CD  . GLU B 2 11  ? -33.725 -9.244  -88.048  1.00 135.34 ? 11  GLU B CD  1 
ATOM   2622  O OE1 . GLU B 2 11  ? -32.830 -9.646  -87.324  1.00 135.32 ? 11  GLU B OE1 1 
ATOM   2623  O OE2 . GLU B 2 11  ? -33.690 -9.342  -89.305  1.00 127.09 ? 11  GLU B OE2 1 
ATOM   2624  N N   . GLY B 2 12  ? -35.985 -10.069 -83.724  1.00 114.31 ? 12  GLY B N   1 
ATOM   2625  C CA  . GLY B 2 12  ? -37.297 -10.476 -83.259  1.00 110.57 ? 12  GLY B CA  1 
ATOM   2626  C C   . GLY B 2 12  ? -37.316 -11.180 -81.917  1.00 110.32 ? 12  GLY B C   1 
ATOM   2627  O O   . GLY B 2 12  ? -36.802 -10.667 -80.919  1.00 112.26 ? 12  GLY B O   1 
ATOM   2628  N N   . GLY B 2 13  ? -37.925 -12.362 -81.891  1.00 106.68 ? 13  GLY B N   1 
ATOM   2629  C CA  . GLY B 2 13  ? -38.088 -13.155 -80.689  1.00 93.32  ? 13  GLY B CA  1 
ATOM   2630  C C   . GLY B 2 13  ? -39.134 -14.223 -80.927  1.00 93.35  ? 13  GLY B C   1 
ATOM   2631  O O   . GLY B 2 13  ? -40.169 -13.948 -81.540  1.00 100.03 ? 13  GLY B O   1 
ATOM   2632  N N   . TRP B 2 14  ? -38.890 -15.440 -80.450  1.00 91.52  ? 14  TRP B N   1 
ATOM   2633  C CA  . TRP B 2 14  ? -39.692 -16.601 -80.835  1.00 91.77  ? 14  TRP B CA  1 
ATOM   2634  C C   . TRP B 2 14  ? -40.706 -16.910 -79.739  1.00 90.36  ? 14  TRP B C   1 
ATOM   2635  O O   . TRP B 2 14  ? -40.374 -17.522 -78.720  1.00 89.51  ? 14  TRP B O   1 
ATOM   2636  C CB  . TRP B 2 14  ? -38.791 -17.797 -81.123  1.00 93.01  ? 14  TRP B CB  1 
ATOM   2637  C CG  . TRP B 2 14  ? -37.922 -17.590 -82.327  1.00 91.37  ? 14  TRP B CG  1 
ATOM   2638  C CD1 . TRP B 2 14  ? -38.024 -16.587 -83.247  1.00 88.75  ? 14  TRP B CD1 1 
ATOM   2639  C CD2 . TRP B 2 14  ? -36.814 -18.399 -82.738  1.00 86.31  ? 14  TRP B CD2 1 
ATOM   2640  N NE1 . TRP B 2 14  ? -37.051 -16.722 -84.207  1.00 84.29  ? 14  TRP B NE1 1 
ATOM   2641  C CE2 . TRP B 2 14  ? -36.294 -17.827 -83.917  1.00 97.38  ? 14  TRP B CE2 1 
ATOM   2642  C CE3 . TRP B 2 14  ? -36.212 -19.551 -82.226  1.00 84.64  ? 14  TRP B CE3 1 
ATOM   2643  C CZ2 . TRP B 2 14  ? -35.203 -18.369 -84.591  1.00 98.13  ? 14  TRP B CZ2 1 
ATOM   2644  C CZ3 . TRP B 2 14  ? -35.127 -20.086 -82.895  1.00 95.95  ? 14  TRP B CZ3 1 
ATOM   2645  C CH2 . TRP B 2 14  ? -34.634 -19.496 -84.065  1.00 101.01 ? 14  TRP B CH2 1 
ATOM   2646  N N   . GLN B 2 15  ? -41.953 -16.486 -79.962  1.00 86.44  ? 15  GLN B N   1 
ATOM   2647  C CA  . GLN B 2 15  ? -43.039 -16.859 -79.063  1.00 100.63 ? 15  GLN B CA  1 
ATOM   2648  C C   . GLN B 2 15  ? -43.303 -18.358 -79.098  1.00 93.31  ? 15  GLN B C   1 
ATOM   2649  O O   . GLN B 2 15  ? -43.747 -18.932 -78.097  1.00 97.23  ? 15  GLN B O   1 
ATOM   2650  C CB  . GLN B 2 15  ? -44.311 -16.092 -79.431  1.00 105.28 ? 15  GLN B CB  1 
ATOM   2651  C CG  . GLN B 2 15  ? -44.193 -14.577 -79.342  1.00 102.30 ? 15  GLN B CG  1 
ATOM   2652  C CD  . GLN B 2 15  ? -44.546 -14.040 -77.968  1.00 105.21 ? 15  GLN B CD  1 
ATOM   2653  O OE1 . GLN B 2 15  ? -44.882 -14.799 -77.058  1.00 98.47  ? 15  GLN B OE1 1 
ATOM   2654  N NE2 . GLN B 2 15  ? -44.477 -12.722 -77.813  1.00 103.52 ? 15  GLN B NE2 1 
ATOM   2655  N N   . GLY B 2 16  ? -43.037 -19.006 -80.234  1.00 89.75  ? 16  GLY B N   1 
ATOM   2656  C CA  . GLY B 2 16  ? -43.296 -20.425 -80.387  1.00 104.86 ? 16  GLY B CA  1 
ATOM   2657  C C   . GLY B 2 16  ? -42.294 -21.344 -79.725  1.00 100.30 ? 16  GLY B C   1 
ATOM   2658  O O   . GLY B 2 16  ? -42.545 -22.550 -79.640  1.00 97.48  ? 16  GLY B O   1 
ATOM   2659  N N   . MET B 2 17  ? -41.168 -20.811 -79.261  1.00 101.19 ? 17  MET B N   1 
ATOM   2660  C CA  . MET B 2 17  ? -40.167 -21.598 -78.550  1.00 101.32 ? 17  MET B CA  1 
ATOM   2661  C C   . MET B 2 17  ? -40.453 -21.494 -77.057  1.00 101.24 ? 17  MET B C   1 
ATOM   2662  O O   . MET B 2 17  ? -40.271 -20.431 -76.455  1.00 105.89 ? 17  MET B O   1 
ATOM   2663  C CB  . MET B 2 17  ? -38.762 -21.108 -78.889  1.00 93.55  ? 17  MET B CB  1 
ATOM   2664  C CG  . MET B 2 17  ? -37.645 -21.896 -78.236  1.00 94.56  ? 17  MET B CG  1 
ATOM   2665  S SD  . MET B 2 17  ? -36.041 -21.351 -78.841  1.00 98.41  ? 17  MET B SD  1 
ATOM   2666  C CE  . MET B 2 17  ? -36.233 -19.576 -78.709  1.00 91.92  ? 17  MET B CE  1 
ATOM   2667  N N   . VAL B 2 18  ? -40.903 -22.598 -76.459  1.00 97.49  ? 18  VAL B N   1 
ATOM   2668  C CA  . VAL B 2 18  ? -41.397 -22.608 -75.090  1.00 99.68  ? 18  VAL B CA  1 
ATOM   2669  C C   . VAL B 2 18  ? -40.580 -23.525 -74.189  1.00 107.75 ? 18  VAL B C   1 
ATOM   2670  O O   . VAL B 2 18  ? -40.998 -23.816 -73.067  1.00 111.29 ? 18  VAL B O   1 
ATOM   2671  C CB  . VAL B 2 18  ? -42.890 -22.994 -75.045  1.00 98.17  ? 18  VAL B CB  1 
ATOM   2672  C CG1 . VAL B 2 18  ? -43.695 -22.119 -75.996  1.00 94.22  ? 18  VAL B CG1 1 
ATOM   2673  C CG2 . VAL B 2 18  ? -43.072 -24.467 -75.385  1.00 89.05  ? 18  VAL B CG2 1 
ATOM   2674  N N   . ASP B 2 19  ? -39.415 -23.980 -74.648  1.00 103.86 ? 19  ASP B N   1 
ATOM   2675  C CA  . ASP B 2 19  ? -38.622 -24.956 -73.910  1.00 99.98  ? 19  ASP B CA  1 
ATOM   2676  C C   . ASP B 2 19  ? -37.213 -24.467 -73.590  1.00 109.31 ? 19  ASP B C   1 
ATOM   2677  O O   . ASP B 2 19  ? -36.386 -25.262 -73.127  1.00 109.34 ? 19  ASP B O   1 
ATOM   2678  C CB  . ASP B 2 19  ? -38.557 -26.272 -74.690  1.00 109.74 ? 19  ASP B CB  1 
ATOM   2679  C CG  . ASP B 2 19  ? -38.384 -26.056 -76.182  1.00 119.88 ? 19  ASP B CG  1 
ATOM   2680  O OD1 . ASP B 2 19  ? -38.817 -24.997 -76.684  1.00 117.34 ? 19  ASP B OD1 1 
ATOM   2681  O OD2 . ASP B 2 19  ? -37.819 -26.946 -76.854  1.00 119.89 ? 19  ASP B OD2 1 
ATOM   2682  N N   . GLY B 2 20  ? -36.918 -23.192 -73.814  1.00 96.64  ? 20  GLY B N   1 
ATOM   2683  C CA  . GLY B 2 20  ? -35.593 -22.680 -73.520  1.00 91.67  ? 20  GLY B CA  1 
ATOM   2684  C C   . GLY B 2 20  ? -35.526 -21.194 -73.792  1.00 100.16 ? 20  GLY B C   1 
ATOM   2685  O O   . GLY B 2 20  ? -36.510 -20.563 -74.192  1.00 100.45 ? 20  GLY B O   1 
ATOM   2686  N N   . TRP B 2 21  ? -34.337 -20.637 -73.561  1.00 91.26  ? 21  TRP B N   1 
ATOM   2687  C CA  . TRP B 2 21  ? -34.079 -19.222 -73.802  1.00 97.66  ? 21  TRP B CA  1 
ATOM   2688  C C   . TRP B 2 21  ? -33.426 -18.960 -75.151  1.00 91.69  ? 21  TRP B C   1 
ATOM   2689  O O   . TRP B 2 21  ? -33.817 -18.019 -75.847  1.00 90.47  ? 21  TRP B O   1 
ATOM   2690  C CB  . TRP B 2 21  ? -33.201 -18.644 -72.688  1.00 99.29  ? 21  TRP B CB  1 
ATOM   2691  C CG  . TRP B 2 21  ? -33.939 -18.425 -71.403  1.00 99.76  ? 21  TRP B CG  1 
ATOM   2692  C CD1 . TRP B 2 21  ? -35.204 -18.841 -71.104  1.00 104.13 ? 21  TRP B CD1 1 
ATOM   2693  C CD2 . TRP B 2 21  ? -33.464 -17.724 -70.248  1.00 102.02 ? 21  TRP B CD2 1 
ATOM   2694  N NE1 . TRP B 2 21  ? -35.543 -18.450 -69.832  1.00 107.17 ? 21  TRP B NE1 1 
ATOM   2695  C CE2 . TRP B 2 21  ? -34.492 -17.763 -69.285  1.00 110.89 ? 21  TRP B CE2 1 
ATOM   2696  C CE3 . TRP B 2 21  ? -32.266 -17.074 -69.932  1.00 102.10 ? 21  TRP B CE3 1 
ATOM   2697  C CZ2 . TRP B 2 21  ? -34.360 -17.175 -68.028  1.00 108.25 ? 21  TRP B CZ2 1 
ATOM   2698  C CZ3 . TRP B 2 21  ? -32.138 -16.491 -68.683  1.00 106.64 ? 21  TRP B CZ3 1 
ATOM   2699  C CH2 . TRP B 2 21  ? -33.179 -16.546 -67.747  1.00 102.78 ? 21  TRP B CH2 1 
ATOM   2700  N N   . TYR B 2 22  ? -32.439 -19.765 -75.534  1.00 93.89  ? 22  TYR B N   1 
ATOM   2701  C CA  . TYR B 2 22  ? -31.838 -19.703 -76.856  1.00 96.37  ? 22  TYR B CA  1 
ATOM   2702  C C   . TYR B 2 22  ? -32.110 -21.015 -77.579  1.00 100.95 ? 22  TYR B C   1 
ATOM   2703  O O   . TYR B 2 22  ? -32.175 -22.079 -76.955  1.00 98.16  ? 22  TYR B O   1 
ATOM   2704  C CB  . TYR B 2 22  ? -30.324 -19.457 -76.784  1.00 102.40 ? 22  TYR B CB  1 
ATOM   2705  C CG  . TYR B 2 22  ? -29.876 -18.604 -75.617  1.00 104.04 ? 22  TYR B CG  1 
ATOM   2706  C CD1 . TYR B 2 22  ? -30.112 -17.236 -75.599  1.00 101.92 ? 22  TYR B CD1 1 
ATOM   2707  C CD2 . TYR B 2 22  ? -29.202 -19.166 -74.541  1.00 96.35  ? 22  TYR B CD2 1 
ATOM   2708  C CE1 . TYR B 2 22  ? -29.695 -16.452 -74.538  1.00 100.97 ? 22  TYR B CE1 1 
ATOM   2709  C CE2 . TYR B 2 22  ? -28.783 -18.391 -73.475  1.00 96.03  ? 22  TYR B CE2 1 
ATOM   2710  C CZ  . TYR B 2 22  ? -29.033 -17.034 -73.478  1.00 100.41 ? 22  TYR B CZ  1 
ATOM   2711  O OH  . TYR B 2 22  ? -28.620 -16.255 -72.421  1.00 87.15  ? 22  TYR B OH  1 
ATOM   2712  N N   . GLY B 2 23  ? -32.269 -20.942 -78.894  1.00 87.91  ? 23  GLY B N   1 
ATOM   2713  C CA  . GLY B 2 23  ? -32.600 -22.147 -79.624  1.00 100.37 ? 23  GLY B CA  1 
ATOM   2714  C C   . GLY B 2 23  ? -32.479 -21.974 -81.121  1.00 98.79  ? 23  GLY B C   1 
ATOM   2715  O O   . GLY B 2 23  ? -31.915 -20.996 -81.615  1.00 92.13  ? 23  GLY B O   1 
ATOM   2716  N N   . TYR B 2 24  ? -33.026 -22.957 -81.836  1.00 99.79  ? 24  TYR B N   1 
ATOM   2717  C CA  . TYR B 2 24  ? -32.951 -23.026 -83.286  1.00 96.68  ? 24  TYR B CA  1 
ATOM   2718  C C   . TYR B 2 24  ? -34.347 -23.176 -83.871  1.00 97.07  ? 24  TYR B C   1 
ATOM   2719  O O   . TYR B 2 24  ? -35.250 -23.732 -83.238  1.00 88.39  ? 24  TYR B O   1 
ATOM   2720  C CB  . TYR B 2 24  ? -32.086 -24.208 -83.755  1.00 82.86  ? 24  TYR B CB  1 
ATOM   2721  C CG  . TYR B 2 24  ? -30.726 -24.298 -83.104  1.00 86.02  ? 24  TYR B CG  1 
ATOM   2722  C CD1 . TYR B 2 24  ? -29.620 -23.687 -83.677  1.00 89.04  ? 24  TYR B CD1 1 
ATOM   2723  C CD2 . TYR B 2 24  ? -30.544 -25.010 -81.925  1.00 84.66  ? 24  TYR B CD2 1 
ATOM   2724  C CE1 . TYR B 2 24  ? -28.372 -23.772 -83.089  1.00 95.33  ? 24  TYR B CE1 1 
ATOM   2725  C CE2 . TYR B 2 24  ? -29.301 -25.101 -81.330  1.00 81.83  ? 24  TYR B CE2 1 
ATOM   2726  C CZ  . TYR B 2 24  ? -28.218 -24.480 -81.916  1.00 88.45  ? 24  TYR B CZ  1 
ATOM   2727  O OH  . TYR B 2 24  ? -26.977 -24.568 -81.328  1.00 88.48  ? 24  TYR B OH  1 
ATOM   2728  N N   . HIS B 2 25  ? -34.515 -22.669 -85.090  1.00 100.83 ? 25  HIS B N   1 
ATOM   2729  C CA  . HIS B 2 25  ? -35.715 -22.899 -85.886  1.00 102.23 ? 25  HIS B CA  1 
ATOM   2730  C C   . HIS B 2 25  ? -35.284 -23.438 -87.239  1.00 100.86 ? 25  HIS B C   1 
ATOM   2731  O O   . HIS B 2 25  ? -34.559 -22.762 -87.975  1.00 100.17 ? 25  HIS B O   1 
ATOM   2732  C CB  . HIS B 2 25  ? -36.535 -21.617 -86.057  1.00 101.91 ? 25  HIS B CB  1 
ATOM   2733  C CG  . HIS B 2 25  ? -37.572 -21.706 -87.133  1.00 105.61 ? 25  HIS B CG  1 
ATOM   2734  N ND1 . HIS B 2 25  ? -38.670 -22.534 -87.043  1.00 103.76 ? 25  HIS B ND1 1 
ATOM   2735  C CD2 . HIS B 2 25  ? -37.674 -21.075 -88.327  1.00 108.31 ? 25  HIS B CD2 1 
ATOM   2736  C CE1 . HIS B 2 25  ? -39.406 -22.406 -88.133  1.00 105.04 ? 25  HIS B CE1 1 
ATOM   2737  N NE2 . HIS B 2 25  ? -38.823 -21.527 -88.928  1.00 108.95 ? 25  HIS B NE2 1 
ATOM   2738  N N   . HIS B 2 26  ? -35.726 -24.646 -87.565  1.00 97.36  ? 26  HIS B N   1 
ATOM   2739  C CA  . HIS B 2 26  ? -35.347 -25.278 -88.818  1.00 99.24  ? 26  HIS B CA  1 
ATOM   2740  C C   . HIS B 2 26  ? -36.493 -25.212 -89.822  1.00 100.02 ? 26  HIS B C   1 
ATOM   2741  O O   . HIS B 2 26  ? -37.656 -25.005 -89.467  1.00 95.70  ? 26  HIS B O   1 
ATOM   2742  C CB  . HIS B 2 26  ? -34.899 -26.731 -88.588  1.00 86.99  ? 26  HIS B CB  1 
ATOM   2743  C CG  . HIS B 2 26  ? -35.958 -27.637 -88.032  1.00 89.26  ? 26  HIS B CG  1 
ATOM   2744  N ND1 . HIS B 2 26  ? -35.655 -28.836 -87.423  1.00 92.30  ? 26  HIS B ND1 1 
ATOM   2745  C CD2 . HIS B 2 26  ? -37.308 -27.537 -88.008  1.00 104.09 ? 26  HIS B CD2 1 
ATOM   2746  C CE1 . HIS B 2 26  ? -36.771 -29.430 -87.040  1.00 93.70  ? 26  HIS B CE1 1 
ATOM   2747  N NE2 . HIS B 2 26  ? -37.789 -28.662 -87.384  1.00 101.11 ? 26  HIS B NE2 1 
ATOM   2748  N N   . SER B 2 27  ? -36.140 -25.363 -91.098  1.00 102.11 ? 27  SER B N   1 
ATOM   2749  C CA  . SER B 2 27  ? -37.136 -25.426 -92.167  1.00 104.36 ? 27  SER B CA  1 
ATOM   2750  C C   . SER B 2 27  ? -36.525 -26.251 -93.295  1.00 103.84 ? 27  SER B C   1 
ATOM   2751  O O   . SER B 2 27  ? -35.710 -25.741 -94.070  1.00 105.89 ? 27  SER B O   1 
ATOM   2752  C CB  . SER B 2 27  ? -37.538 -24.037 -92.644  1.00 102.87 ? 27  SER B CB  1 
ATOM   2753  O OG  . SER B 2 27  ? -36.700 -23.596 -93.698  1.00 113.39 ? 27  SER B OG  1 
ATOM   2754  N N   . ASN B 2 28  ? -36.917 -27.521 -93.374  1.00 100.63 ? 28  ASN B N   1 
ATOM   2755  C CA  . ASN B 2 28  ? -36.410 -28.408 -94.413  1.00 101.39 ? 28  ASN B CA  1 
ATOM   2756  C C   . ASN B 2 28  ? -37.567 -29.083 -95.138  1.00 102.66 ? 28  ASN B C   1 
ATOM   2757  O O   . ASN B 2 28  ? -38.728 -28.702 -94.954  1.00 87.33  ? 28  ASN B O   1 
ATOM   2758  C CB  . ASN B 2 28  ? -35.456 -29.447 -93.818  1.00 90.72  ? 28  ASN B CB  1 
ATOM   2759  C CG  . ASN B 2 28  ? -36.123 -30.333 -92.783  1.00 98.10  ? 28  ASN B CG  1 
ATOM   2760  O OD1 . ASN B 2 28  ? -37.177 -29.996 -92.244  1.00 96.63  ? 28  ASN B OD1 1 
ATOM   2761  N ND2 . ASN B 2 28  ? -35.505 -31.473 -92.494  1.00 98.55  ? 28  ASN B ND2 1 
ATOM   2762  N N   . GLU B 2 29  ? -37.259 -30.080 -95.969  1.00 105.04 ? 29  GLU B N   1 
ATOM   2763  C CA  . GLU B 2 29  ? -38.298 -30.764 -96.730  1.00 102.50 ? 29  GLU B CA  1 
ATOM   2764  C C   . GLU B 2 29  ? -39.303 -31.475 -95.833  1.00 96.00  ? 29  GLU B C   1 
ATOM   2765  O O   . GLU B 2 29  ? -40.426 -31.744 -96.272  1.00 90.43  ? 29  GLU B O   1 
ATOM   2766  C CB  . GLU B 2 29  ? -37.665 -31.767 -97.698  1.00 98.96  ? 29  GLU B CB  1 
ATOM   2767  C CG  . GLU B 2 29  ? -38.204 -31.687 -99.117  1.00 103.56 ? 29  GLU B CG  1 
ATOM   2768  C CD  . GLU B 2 29  ? -37.702 -30.464 -99.862  1.00 113.82 ? 29  GLU B CD  1 
ATOM   2769  O OE1 . GLU B 2 29  ? -36.487 -30.181 -99.790  1.00 114.93 ? 29  GLU B OE1 1 
ATOM   2770  O OE2 . GLU B 2 29  ? -38.522 -29.783 -100.514 1.00 109.41 ? 29  GLU B OE2 1 
ATOM   2771  N N   . GLN B 2 30  ? -38.931 -31.779 -94.590  1.00 97.63  ? 30  GLN B N   1 
ATOM   2772  C CA  . GLN B 2 30  ? -39.803 -32.510 -93.680  1.00 93.01  ? 30  GLN B CA  1 
ATOM   2773  C C   . GLN B 2 30  ? -40.687 -31.606 -92.828  1.00 91.98  ? 30  GLN B C   1 
ATOM   2774  O O   . GLN B 2 30  ? -41.554 -32.116 -92.111  1.00 87.26  ? 30  GLN B O   1 
ATOM   2775  C CB  . GLN B 2 30  ? -38.967 -33.418 -92.770  1.00 85.80  ? 30  GLN B CB  1 
ATOM   2776  C CG  . GLN B 2 30  ? -37.907 -34.220 -93.515  1.00 88.90  ? 30  GLN B CG  1 
ATOM   2777  C CD  . GLN B 2 30  ? -37.353 -35.371 -92.697  1.00 88.29  ? 30  GLN B CD  1 
ATOM   2778  O OE1 . GLN B 2 30  ? -36.160 -35.415 -92.394  1.00 86.88  ? 30  GLN B OE1 1 
ATOM   2779  N NE2 . GLN B 2 30  ? -38.217 -36.318 -92.345  1.00 77.36  ? 30  GLN B NE2 1 
ATOM   2780  N N   . GLY B 2 31  ? -40.496 -30.284 -92.883  1.00 95.24  ? 31  GLY B N   1 
ATOM   2781  C CA  . GLY B 2 31  ? -41.325 -29.354 -92.151  1.00 99.77  ? 31  GLY B CA  1 
ATOM   2782  C C   . GLY B 2 31  ? -40.483 -28.330 -91.421  1.00 104.80 ? 31  GLY B C   1 
ATOM   2783  O O   . GLY B 2 31  ? -39.299 -28.137 -91.722  1.00 94.68  ? 31  GLY B O   1 
ATOM   2784  N N   . SER B 2 32  ? -41.108 -27.663 -90.452  1.00 109.43 ? 32  SER B N   1 
ATOM   2785  C CA  . SER B 2 32  ? -40.462 -26.643 -89.639  1.00 101.34 ? 32  SER B CA  1 
ATOM   2786  C C   . SER B 2 32  ? -40.760 -26.902 -88.167  1.00 102.31 ? 32  SER B C   1 
ATOM   2787  O O   . SER B 2 32  ? -41.645 -27.686 -87.815  1.00 105.64 ? 32  SER B O   1 
ATOM   2788  C CB  . SER B 2 32  ? -40.921 -25.231 -90.033  1.00 98.62  ? 32  SER B CB  1 
ATOM   2789  O OG  . SER B 2 32  ? -40.443 -24.874 -91.319  1.00 95.14  ? 32  SER B OG  1 
ATOM   2790  N N   . GLY B 2 33  ? -40.006 -26.232 -87.305  1.00 103.09 ? 33  GLY B N   1 
ATOM   2791  C CA  . GLY B 2 33  ? -40.186 -26.392 -85.876  1.00 104.05 ? 33  GLY B CA  1 
ATOM   2792  C C   . GLY B 2 33  ? -39.118 -25.644 -85.110  1.00 104.27 ? 33  GLY B C   1 
ATOM   2793  O O   . GLY B 2 33  ? -38.206 -25.041 -85.685  1.00 95.41  ? 33  GLY B O   1 
ATOM   2794  N N   . TYR B 2 34  ? -39.249 -25.699 -83.786  1.00 97.20  ? 34  TYR B N   1 
ATOM   2795  C CA  . TYR B 2 34  ? -38.333 -25.037 -82.871  1.00 88.59  ? 34  TYR B CA  1 
ATOM   2796  C C   . TYR B 2 34  ? -37.614 -26.067 -82.010  1.00 87.70  ? 34  TYR B C   1 
ATOM   2797  O O   . TYR B 2 34  ? -38.175 -27.109 -81.659  1.00 94.56  ? 34  TYR B O   1 
ATOM   2798  C CB  . TYR B 2 34  ? -39.065 -24.039 -81.963  1.00 94.90  ? 34  TYR B CB  1 
ATOM   2799  C CG  . TYR B 2 34  ? -39.691 -22.871 -82.690  1.00 88.16  ? 34  TYR B CG  1 
ATOM   2800  C CD1 . TYR B 2 34  ? -41.052 -22.851 -82.969  1.00 86.29  ? 34  TYR B CD1 1 
ATOM   2801  C CD2 . TYR B 2 34  ? -38.922 -21.787 -83.094  1.00 89.47  ? 34  TYR B CD2 1 
ATOM   2802  C CE1 . TYR B 2 34  ? -41.629 -21.784 -83.631  1.00 87.98  ? 34  TYR B CE1 1 
ATOM   2803  C CE2 . TYR B 2 34  ? -39.490 -20.715 -83.758  1.00 87.75  ? 34  TYR B CE2 1 
ATOM   2804  C CZ  . TYR B 2 34  ? -40.845 -20.719 -84.024  1.00 100.03 ? 34  TYR B CZ  1 
ATOM   2805  O OH  . TYR B 2 34  ? -41.416 -19.656 -84.685  1.00 99.01  ? 34  TYR B OH  1 
ATOM   2806  N N   . ALA B 2 35  ? -36.363 -25.762 -81.674  1.00 84.32  ? 35  ALA B N   1 
ATOM   2807  C CA  . ALA B 2 35  ? -35.571 -26.607 -80.790  1.00 93.22  ? 35  ALA B CA  1 
ATOM   2808  C C   . ALA B 2 35  ? -34.586 -25.726 -80.038  1.00 103.14 ? 35  ALA B C   1 
ATOM   2809  O O   . ALA B 2 35  ? -33.938 -24.867 -80.642  1.00 100.31 ? 35  ALA B O   1 
ATOM   2810  C CB  . ALA B 2 35  ? -34.833 -27.697 -81.572  1.00 80.13  ? 35  ALA B CB  1 
ATOM   2811  N N   . ALA B 2 36  ? -34.473 -25.945 -78.732  1.00 98.96  ? 36  ALA B N   1 
ATOM   2812  C CA  . ALA B 2 36  ? -33.643 -25.117 -77.869  1.00 99.38  ? 36  ALA B CA  1 
ATOM   2813  C C   . ALA B 2 36  ? -32.346 -25.836 -77.521  1.00 88.69  ? 36  ALA B C   1 
ATOM   2814  O O   . ALA B 2 36  ? -32.346 -27.036 -77.232  1.00 83.71  ? 36  ALA B O   1 
ATOM   2815  C CB  . ALA B 2 36  ? -34.392 -24.747 -76.587  1.00 100.08 ? 36  ALA B CB  1 
ATOM   2816  N N   . ASP B 2 37  ? -31.240 -25.092 -77.553  1.00 85.87  ? 37  ASP B N   1 
ATOM   2817  C CA  . ASP B 2 37  ? -29.950 -25.627 -77.130  1.00 96.04  ? 37  ASP B CA  1 
ATOM   2818  C C   . ASP B 2 37  ? -29.959 -25.789 -75.616  1.00 95.74  ? 37  ASP B C   1 
ATOM   2819  O O   . ASP B 2 37  ? -29.929 -24.799 -74.878  1.00 93.93  ? 37  ASP B O   1 
ATOM   2820  C CB  . ASP B 2 37  ? -28.816 -24.708 -77.576  1.00 93.92  ? 37  ASP B CB  1 
ATOM   2821  C CG  . ASP B 2 37  ? -27.447 -25.232 -77.178  1.00 104.04 ? 37  ASP B CG  1 
ATOM   2822  O OD1 . ASP B 2 37  ? -27.333 -26.434 -76.852  1.00 100.71 ? 37  ASP B OD1 1 
ATOM   2823  O OD2 . ASP B 2 37  ? -26.483 -24.440 -77.184  1.00 103.04 ? 37  ASP B OD2 1 
ATOM   2824  N N   . LYS B 2 38  ? -29.990 -27.041 -75.153  1.00 93.49  ? 38  LYS B N   1 
ATOM   2825  C CA  . LYS B 2 38  ? -30.134 -27.314 -73.727  1.00 95.68  ? 38  LYS B CA  1 
ATOM   2826  C C   . LYS B 2 38  ? -28.935 -26.825 -72.921  1.00 100.89 ? 38  LYS B C   1 
ATOM   2827  O O   . LYS B 2 38  ? -29.100 -26.362 -71.786  1.00 97.78  ? 38  LYS B O   1 
ATOM   2828  C CB  . LYS B 2 38  ? -30.354 -28.813 -73.515  1.00 102.82 ? 38  LYS B CB  1 
ATOM   2829  C CG  . LYS B 2 38  ? -30.131 -29.310 -72.096  1.00 112.72 ? 38  LYS B CG  1 
ATOM   2830  C CD  . LYS B 2 38  ? -30.462 -30.791 -71.993  1.00 110.80 ? 38  LYS B CD  1 
ATOM   2831  C CE  . LYS B 2 38  ? -29.825 -31.426 -70.768  1.00 107.84 ? 38  LYS B CE  1 
ATOM   2832  N NZ  . LYS B 2 38  ? -30.156 -32.875 -70.672  1.00 105.43 ? 38  LYS B NZ  1 
ATOM   2833  N N   . GLU B 2 39  ? -27.727 -26.907 -73.483  1.00 97.92  ? 39  GLU B N   1 
ATOM   2834  C CA  . GLU B 2 39  ? -26.535 -26.603 -72.697  1.00 92.92  ? 39  GLU B CA  1 
ATOM   2835  C C   . GLU B 2 39  ? -26.343 -25.102 -72.503  1.00 101.20 ? 39  GLU B C   1 
ATOM   2836  O O   . GLU B 2 39  ? -26.200 -24.632 -71.368  1.00 93.18  ? 39  GLU B O   1 
ATOM   2837  C CB  . GLU B 2 39  ? -25.297 -27.225 -73.350  1.00 108.89 ? 39  GLU B CB  1 
ATOM   2838  C CG  . GLU B 2 39  ? -25.290 -28.752 -73.355  1.00 116.97 ? 39  GLU B CG  1 
ATOM   2839  C CD  . GLU B 2 39  ? -25.367 -29.361 -71.960  1.00 120.30 ? 39  GLU B CD  1 
ATOM   2840  O OE1 . GLU B 2 39  ? -25.129 -28.638 -70.967  1.00 125.10 ? 39  GLU B OE1 1 
ATOM   2841  O OE2 . GLU B 2 39  ? -25.664 -30.570 -71.857  1.00 117.77 ? 39  GLU B OE2 1 
ATOM   2842  N N   . SER B 2 40  ? -26.325 -24.333 -73.595  1.00 104.19 ? 40  SER B N   1 
ATOM   2843  C CA  . SER B 2 40  ? -26.106 -22.896 -73.466  1.00 94.41  ? 40  SER B CA  1 
ATOM   2844  C C   . SER B 2 40  ? -27.245 -22.217 -72.717  1.00 101.43 ? 40  SER B C   1 
ATOM   2845  O O   . SER B 2 40  ? -27.026 -21.199 -72.051  1.00 97.86  ? 40  SER B O   1 
ATOM   2846  C CB  . SER B 2 40  ? -25.924 -22.258 -74.842  1.00 91.73  ? 40  SER B CB  1 
ATOM   2847  O OG  . SER B 2 40  ? -27.114 -22.346 -75.607  1.00 107.06 ? 40  SER B OG  1 
ATOM   2848  N N   . THR B 2 41  ? -28.462 -22.759 -72.810  1.00 100.83 ? 41  THR B N   1 
ATOM   2849  C CA  . THR B 2 41  ? -29.578 -22.171 -72.080  1.00 94.34  ? 41  THR B CA  1 
ATOM   2850  C C   . THR B 2 41  ? -29.510 -22.490 -70.591  1.00 94.63  ? 41  THR B C   1 
ATOM   2851  O O   . THR B 2 41  ? -29.961 -21.684 -69.771  1.00 86.44  ? 41  THR B O   1 
ATOM   2852  C CB  . THR B 2 41  ? -30.914 -22.631 -72.681  1.00 96.23  ? 41  THR B CB  1 
ATOM   2853  O OG1 . THR B 2 41  ? -31.927 -21.657 -72.403  1.00 105.90 ? 41  THR B OG1 1 
ATOM   2854  C CG2 . THR B 2 41  ? -31.355 -23.977 -72.114  1.00 99.57  ? 41  THR B CG2 1 
ATOM   2855  N N   . GLN B 2 42  ? -28.947 -23.643 -70.218  1.00 96.83  ? 42  GLN B N   1 
ATOM   2856  C CA  . GLN B 2 42  ? -28.775 -23.947 -68.804  1.00 91.12  ? 42  GLN B CA  1 
ATOM   2857  C C   . GLN B 2 42  ? -27.589 -23.200 -68.210  1.00 94.86  ? 42  GLN B C   1 
ATOM   2858  O O   . GLN B 2 42  ? -27.627 -22.817 -67.036  1.00 101.18 ? 42  GLN B O   1 
ATOM   2859  C CB  . GLN B 2 42  ? -28.623 -25.455 -68.600  1.00 86.54  ? 42  GLN B CB  1 
ATOM   2860  C CG  . GLN B 2 42  ? -28.885 -25.905 -67.171  1.00 91.68  ? 42  GLN B CG  1 
ATOM   2861  C CD  . GLN B 2 42  ? -30.000 -25.114 -66.510  1.00 101.87 ? 42  GLN B CD  1 
ATOM   2862  O OE1 . GLN B 2 42  ? -29.744 -24.169 -65.764  1.00 103.54 ? 42  GLN B OE1 1 
ATOM   2863  N NE2 . GLN B 2 42  ? -31.243 -25.497 -66.779  1.00 90.05  ? 42  GLN B NE2 1 
ATOM   2864  N N   . LYS B 2 43  ? -26.535 -22.985 -69.002  1.00 100.33 ? 43  LYS B N   1 
ATOM   2865  C CA  . LYS B 2 43  ? -25.445 -22.120 -68.566  1.00 92.83  ? 43  LYS B CA  1 
ATOM   2866  C C   . LYS B 2 43  ? -25.948 -20.717 -68.259  1.00 99.00  ? 43  LYS B C   1 
ATOM   2867  O O   . LYS B 2 43  ? -25.435 -20.054 -67.350  1.00 100.21 ? 43  LYS B O   1 
ATOM   2868  C CB  . LYS B 2 43  ? -24.356 -22.071 -69.640  1.00 96.49  ? 43  LYS B CB  1 
ATOM   2869  C CG  . LYS B 2 43  ? -22.986 -21.649 -69.136  1.00 105.38 ? 43  LYS B CG  1 
ATOM   2870  C CD  . LYS B 2 43  ? -22.223 -22.839 -68.577  1.00 116.84 ? 43  LYS B CD  1 
ATOM   2871  C CE  . LYS B 2 43  ? -22.013 -23.905 -69.643  1.00 109.54 ? 43  LYS B CE  1 
ATOM   2872  N NZ  . LYS B 2 43  ? -21.299 -25.099 -69.110  1.00 116.06 ? 43  LYS B NZ  1 
ATOM   2873  N N   . ALA B 2 44  ? -26.952 -20.250 -69.006  1.00 88.96  ? 44  ALA B N   1 
ATOM   2874  C CA  . ALA B 2 44  ? -27.523 -18.935 -68.743  1.00 84.96  ? 44  ALA B CA  1 
ATOM   2875  C C   . ALA B 2 44  ? -28.363 -18.935 -67.472  1.00 91.23  ? 44  ALA B C   1 
ATOM   2876  O O   . ALA B 2 44  ? -28.248 -18.017 -66.651  1.00 95.28  ? 44  ALA B O   1 
ATOM   2877  C CB  . ALA B 2 44  ? -28.358 -18.478 -69.938  1.00 84.83  ? 44  ALA B CB  1 
ATOM   2878  N N   . ILE B 2 45  ? -29.210 -19.953 -67.286  1.00 84.46  ? 45  ILE B N   1 
ATOM   2879  C CA  . ILE B 2 45  ? -30.118 -19.968 -66.138  1.00 88.70  ? 45  ILE B CA  1 
ATOM   2880  C C   . ILE B 2 45  ? -29.330 -20.023 -64.835  1.00 98.00  ? 45  ILE B C   1 
ATOM   2881  O O   . ILE B 2 45  ? -29.596 -19.262 -63.898  1.00 93.91  ? 45  ILE B O   1 
ATOM   2882  C CB  . ILE B 2 45  ? -31.117 -21.137 -66.244  1.00 93.69  ? 45  ILE B CB  1 
ATOM   2883  C CG1 . ILE B 2 45  ? -32.419 -20.685 -66.904  1.00 94.22  ? 45  ILE B CG1 1 
ATOM   2884  C CG2 . ILE B 2 45  ? -31.453 -21.689 -64.864  1.00 90.53  ? 45  ILE B CG2 1 
ATOM   2885  C CD1 . ILE B 2 45  ? -32.274 -20.220 -68.320  1.00 94.38  ? 45  ILE B CD1 1 
ATOM   2886  N N   . ASP B 2 46  ? -28.341 -20.918 -64.758  1.00 94.91  ? 46  ASP B N   1 
ATOM   2887  C CA  . ASP B 2 46  ? -27.552 -21.030 -63.535  1.00 101.31 ? 46  ASP B CA  1 
ATOM   2888  C C   . ASP B 2 46  ? -26.720 -19.779 -63.289  1.00 98.93  ? 46  ASP B C   1 
ATOM   2889  O O   . ASP B 2 46  ? -26.369 -19.487 -62.140  1.00 96.71  ? 46  ASP B O   1 
ATOM   2890  C CB  . ASP B 2 46  ? -26.655 -22.267 -63.590  1.00 105.81 ? 46  ASP B CB  1 
ATOM   2891  C CG  . ASP B 2 46  ? -27.363 -23.520 -63.112  1.00 112.23 ? 46  ASP B CG  1 
ATOM   2892  O OD1 . ASP B 2 46  ? -28.194 -23.416 -62.184  1.00 103.48 ? 46  ASP B OD1 1 
ATOM   2893  O OD2 . ASP B 2 46  ? -27.088 -24.608 -63.662  1.00 110.20 ? 46  ASP B OD2 1 
ATOM   2894  N N   . GLY B 2 47  ? -26.399 -19.034 -64.343  1.00 90.61  ? 47  GLY B N   1 
ATOM   2895  C CA  . GLY B 2 47  ? -25.703 -17.775 -64.187  1.00 84.86  ? 47  GLY B CA  1 
ATOM   2896  C C   . GLY B 2 47  ? -26.542 -16.744 -63.459  1.00 90.53  ? 47  GLY B C   1 
ATOM   2897  O O   . GLY B 2 47  ? -26.181 -16.307 -62.362  1.00 97.35  ? 47  GLY B O   1 
ATOM   2898  N N   . VAL B 2 48  ? -27.673 -16.356 -64.055  1.00 79.34  ? 48  VAL B N   1 
ATOM   2899  C CA  . VAL B 2 48  ? -28.524 -15.337 -63.445  1.00 84.89  ? 48  VAL B CA  1 
ATOM   2900  C C   . VAL B 2 48  ? -29.100 -15.823 -62.124  1.00 79.49  ? 48  VAL B C   1 
ATOM   2901  O O   . VAL B 2 48  ? -29.388 -15.016 -61.231  1.00 75.75  ? 48  VAL B O   1 
ATOM   2902  C CB  . VAL B 2 48  ? -29.632 -14.904 -64.423  1.00 84.81  ? 48  VAL B CB  1 
ATOM   2903  C CG1 . VAL B 2 48  ? -29.072 -13.931 -65.432  1.00 79.57  ? 48  VAL B CG1 1 
ATOM   2904  C CG2 . VAL B 2 48  ? -30.223 -16.109 -65.128  1.00 87.52  ? 48  VAL B CG2 1 
ATOM   2905  N N   . THR B 2 49  ? -29.291 -17.136 -61.975  1.00 80.36  ? 49  THR B N   1 
ATOM   2906  C CA  . THR B 2 49  ? -29.660 -17.675 -60.671  1.00 85.19  ? 49  THR B CA  1 
ATOM   2907  C C   . THR B 2 49  ? -28.571 -17.393 -59.643  1.00 88.08  ? 49  THR B C   1 
ATOM   2908  O O   . THR B 2 49  ? -28.862 -16.990 -58.511  1.00 92.41  ? 49  THR B O   1 
ATOM   2909  C CB  . THR B 2 49  ? -29.925 -19.179 -60.773  1.00 90.22  ? 49  THR B CB  1 
ATOM   2910  O OG1 . THR B 2 49  ? -31.158 -19.405 -61.468  1.00 89.15  ? 49  THR B OG1 1 
ATOM   2911  C CG2 . THR B 2 49  ? -30.001 -19.811 -59.391  1.00 87.27  ? 49  THR B CG2 1 
ATOM   2912  N N   . ASN B 2 50  ? -27.309 -17.586 -60.028  1.00 87.44  ? 50  ASN B N   1 
ATOM   2913  C CA  . ASN B 2 50  ? -26.205 -17.281 -59.125  1.00 83.51  ? 50  ASN B CA  1 
ATOM   2914  C C   . ASN B 2 50  ? -26.088 -15.781 -58.879  1.00 85.64  ? 50  ASN B C   1 
ATOM   2915  O O   . ASN B 2 50  ? -25.783 -15.354 -57.760  1.00 81.54  ? 50  ASN B O   1 
ATOM   2916  C CB  . ASN B 2 50  ? -24.901 -17.839 -59.691  1.00 91.13  ? 50  ASN B CB  1 
ATOM   2917  C CG  . ASN B 2 50  ? -23.886 -18.151 -58.612  1.00 94.88  ? 50  ASN B CG  1 
ATOM   2918  O OD1 . ASN B 2 50  ? -23.867 -19.254 -58.067  1.00 90.19  ? 50  ASN B OD1 1 
ATOM   2919  N ND2 . ASN B 2 50  ? -23.034 -17.181 -58.299  1.00 90.02  ? 50  ASN B ND2 1 
ATOM   2920  N N   . LYS B 2 51  ? -26.319 -14.967 -59.915  1.00 81.32  ? 51  LYS B N   1 
ATOM   2921  C CA  . LYS B 2 51  ? -26.234 -13.519 -59.749  1.00 75.47  ? 51  LYS B CA  1 
ATOM   2922  C C   . LYS B 2 51  ? -27.268 -13.012 -58.753  1.00 76.89  ? 51  LYS B C   1 
ATOM   2923  O O   . LYS B 2 51  ? -26.958 -12.172 -57.900  1.00 71.17  ? 51  LYS B O   1 
ATOM   2924  C CB  . LYS B 2 51  ? -26.406 -12.818 -61.097  1.00 71.41  ? 51  LYS B CB  1 
ATOM   2925  C CG  . LYS B 2 51  ? -26.864 -11.372 -60.967  1.00 65.28  ? 51  LYS B CG  1 
ATOM   2926  C CD  . LYS B 2 51  ? -26.113 -10.451 -61.906  1.00 74.31  ? 51  LYS B CD  1 
ATOM   2927  C CE  . LYS B 2 51  ? -26.595 -10.591 -63.338  1.00 86.63  ? 51  LYS B CE  1 
ATOM   2928  N NZ  . LYS B 2 51  ? -25.809 -9.729  -64.268  1.00 65.11  ? 51  LYS B NZ  1 
ATOM   2929  N N   . VAL B 2 52  ? -28.503 -13.509 -58.848  1.00 75.79  ? 52  VAL B N   1 
ATOM   2930  C CA  . VAL B 2 52  ? -29.536 -13.118 -57.894  1.00 72.22  ? 52  VAL B CA  1 
ATOM   2931  C C   . VAL B 2 52  ? -29.162 -13.571 -56.489  1.00 75.86  ? 52  VAL B C   1 
ATOM   2932  O O   . VAL B 2 52  ? -29.302 -12.817 -55.517  1.00 85.30  ? 52  VAL B O   1 
ATOM   2933  C CB  . VAL B 2 52  ? -30.903 -13.678 -58.331  1.00 69.56  ? 52  VAL B CB  1 
ATOM   2934  C CG1 . VAL B 2 52  ? -31.868 -13.726 -57.155  1.00 73.29  ? 52  VAL B CG1 1 
ATOM   2935  C CG2 . VAL B 2 52  ? -31.480 -12.835 -59.456  1.00 67.45  ? 52  VAL B CG2 1 
ATOM   2936  N N   . ASN B 2 53  ? -28.669 -14.804 -56.358  1.00 65.04  ? 53  ASN B N   1 
ATOM   2937  C CA  . ASN B 2 53  ? -28.318 -15.324 -55.041  1.00 74.84  ? 53  ASN B CA  1 
ATOM   2938  C C   . ASN B 2 53  ? -27.076 -14.650 -54.471  1.00 79.70  ? 53  ASN B C   1 
ATOM   2939  O O   . ASN B 2 53  ? -26.964 -14.502 -53.249  1.00 76.83  ? 53  ASN B O   1 
ATOM   2940  C CB  . ASN B 2 53  ? -28.126 -16.837 -55.115  1.00 71.57  ? 53  ASN B CB  1 
ATOM   2941  C CG  . ASN B 2 53  ? -29.434 -17.576 -55.319  1.00 85.87  ? 53  ASN B CG  1 
ATOM   2942  O OD1 . ASN B 2 53  ? -30.499 -16.961 -55.405  1.00 75.08  ? 53  ASN B OD1 1 
ATOM   2943  N ND2 . ASN B 2 53  ? -29.362 -18.899 -55.404  1.00 93.59  ? 53  ASN B ND2 1 
ATOM   2944  N N   . SER B 2 54  ? -26.132 -14.246 -55.326  1.00 74.63  ? 54  SER B N   1 
ATOM   2945  C CA  . SER B 2 54  ? -24.959 -13.528 -54.835  1.00 62.64  ? 54  SER B CA  1 
ATOM   2946  C C   . SER B 2 54  ? -25.338 -12.158 -54.285  1.00 72.02  ? 54  SER B C   1 
ATOM   2947  O O   . SER B 2 54  ? -24.822 -11.735 -53.244  1.00 75.31  ? 54  SER B O   1 
ATOM   2948  C CB  . SER B 2 54  ? -23.919 -13.392 -55.946  1.00 76.11  ? 54  SER B CB  1 
ATOM   2949  O OG  . SER B 2 54  ? -23.364 -14.653 -56.281  1.00 85.41  ? 54  SER B OG  1 
ATOM   2950  N N   . ILE B 2 55  ? -26.241 -11.452 -54.969  1.00 65.73  ? 55  ILE B N   1 
ATOM   2951  C CA  . ILE B 2 55  ? -26.699 -10.153 -54.489  1.00 65.01  ? 55  ILE B CA  1 
ATOM   2952  C C   . ILE B 2 55  ? -27.463 -10.298 -53.176  1.00 73.58  ? 55  ILE B C   1 
ATOM   2953  O O   . ILE B 2 55  ? -27.415 -9.408  -52.317  1.00 69.64  ? 55  ILE B O   1 
ATOM   2954  C CB  . ILE B 2 55  ? -27.540 -9.466  -55.585  1.00 59.88  ? 55  ILE B CB  1 
ATOM   2955  C CG1 . ILE B 2 55  ? -26.623 -8.891  -56.667  1.00 72.54  ? 55  ILE B CG1 1 
ATOM   2956  C CG2 . ILE B 2 55  ? -28.446 -8.386  -55.005  1.00 64.56  ? 55  ILE B CG2 1 
ATOM   2957  C CD1 . ILE B 2 55  ? -27.359 -8.308  -57.855  1.00 73.58  ? 55  ILE B CD1 1 
ATOM   2958  N N   . ILE B 2 56  ? -28.153 -11.421 -52.985  1.00 71.55  ? 56  ILE B N   1 
ATOM   2959  C CA  . ILE B 2 56  ? -28.948 -11.621 -51.777  1.00 70.53  ? 56  ILE B CA  1 
ATOM   2960  C C   . ILE B 2 56  ? -28.078 -12.100 -50.620  1.00 74.53  ? 56  ILE B C   1 
ATOM   2961  O O   . ILE B 2 56  ? -28.093 -11.515 -49.530  1.00 78.08  ? 56  ILE B O   1 
ATOM   2962  C CB  . ILE B 2 56  ? -30.096 -12.608 -52.061  1.00 71.21  ? 56  ILE B CB  1 
ATOM   2963  C CG1 . ILE B 2 56  ? -31.260 -11.893 -52.742  1.00 76.52  ? 56  ILE B CG1 1 
ATOM   2964  C CG2 . ILE B 2 56  ? -30.554 -13.298 -50.782  1.00 68.60  ? 56  ILE B CG2 1 
ATOM   2965  C CD1 . ILE B 2 56  ? -32.297 -12.839 -53.283  1.00 71.64  ? 56  ILE B CD1 1 
ATOM   2966  N N   . ASP B 2 57  ? -27.307 -13.167 -50.837  1.00 72.13  ? 57  ASP B N   1 
ATOM   2967  C CA  . ASP B 2 57  ? -26.649 -13.873 -49.745  1.00 76.79  ? 57  ASP B CA  1 
ATOM   2968  C C   . ASP B 2 57  ? -25.332 -13.243 -49.311  1.00 77.26  ? 57  ASP B C   1 
ATOM   2969  O O   . ASP B 2 57  ? -24.785 -13.651 -48.280  1.00 78.89  ? 57  ASP B O   1 
ATOM   2970  C CB  . ASP B 2 57  ? -26.420 -15.334 -50.138  1.00 83.29  ? 57  ASP B CB  1 
ATOM   2971  C CG  . ASP B 2 57  ? -27.687 -16.164 -50.047  1.00 95.89  ? 57  ASP B CG  1 
ATOM   2972  O OD1 . ASP B 2 57  ? -28.050 -16.577 -48.925  1.00 93.15  ? 57  ASP B OD1 1 
ATOM   2973  O OD2 . ASP B 2 57  ? -28.332 -16.386 -51.094  1.00 96.91  ? 57  ASP B OD2 1 
ATOM   2974  N N   . LYS B 2 58  ? -24.806 -12.273 -50.055  1.00 72.12  ? 58  LYS B N   1 
ATOM   2975  C CA  . LYS B 2 58  ? -23.620 -11.559 -49.602  1.00 69.64  ? 58  LYS B CA  1 
ATOM   2976  C C   . LYS B 2 58  ? -23.950 -10.424 -48.643  1.00 74.36  ? 58  LYS B C   1 
ATOM   2977  O O   . LYS B 2 58  ? -23.029 -9.784  -48.125  1.00 56.14  ? 58  LYS B O   1 
ATOM   2978  C CB  . LYS B 2 58  ? -22.831 -11.014 -50.798  1.00 69.17  ? 58  LYS B CB  1 
ATOM   2979  C CG  . LYS B 2 58  ? -22.058 -12.075 -51.569  1.00 74.76  ? 58  LYS B CG  1 
ATOM   2980  C CD  . LYS B 2 58  ? -21.291 -12.988 -50.625  1.00 73.74  ? 58  LYS B CD  1 
ATOM   2981  C CE  . LYS B 2 58  ? -20.324 -13.888 -51.377  1.00 73.56  ? 58  LYS B CE  1 
ATOM   2982  N NZ  . LYS B 2 58  ? -19.185 -13.118 -51.951  1.00 77.21  ? 58  LYS B NZ  1 
ATOM   2983  N N   . MET B 2 59  ? -25.231 -10.162 -48.394  1.00 65.55  ? 59  MET B N   1 
ATOM   2984  C CA  . MET B 2 59  ? -25.628 -9.125  -47.452  1.00 73.19  ? 59  MET B CA  1 
ATOM   2985  C C   . MET B 2 59  ? -25.458 -9.642  -46.028  1.00 71.27  ? 59  MET B C   1 
ATOM   2986  O O   . MET B 2 59  ? -26.037 -10.669 -45.658  1.00 61.04  ? 59  MET B O   1 
ATOM   2987  C CB  . MET B 2 59  ? -27.072 -8.696  -47.702  1.00 68.92  ? 59  MET B CB  1 
ATOM   2988  C CG  . MET B 2 59  ? -27.583 -7.663  -46.711  1.00 71.71  ? 59  MET B CG  1 
ATOM   2989  S SD  . MET B 2 59  ? -26.614 -6.143  -46.723  1.00 67.45  ? 59  MET B SD  1 
ATOM   2990  C CE  . MET B 2 59  ? -27.551 -5.146  -47.878  1.00 71.11  ? 59  MET B CE  1 
ATOM   2991  N N   . ASN B 2 60  ? -24.663 -8.934  -45.234  1.00 71.53  ? 60  ASN B N   1 
ATOM   2992  C CA  . ASN B 2 60  ? -24.454 -9.286  -43.837  1.00 76.51  ? 60  ASN B CA  1 
ATOM   2993  C C   . ASN B 2 60  ? -25.481 -8.548  -42.985  1.00 68.27  ? 60  ASN B C   1 
ATOM   2994  O O   . ASN B 2 60  ? -25.586 -7.319  -43.056  1.00 65.34  ? 60  ASN B O   1 
ATOM   2995  C CB  . ASN B 2 60  ? -23.031 -8.939  -43.400  1.00 71.30  ? 60  ASN B CB  1 
ATOM   2996  C CG  . ASN B 2 60  ? -22.725 -9.405  -41.992  1.00 78.08  ? 60  ASN B CG  1 
ATOM   2997  O OD1 . ASN B 2 60  ? -22.444 -10.581 -41.761  1.00 84.29  ? 60  ASN B OD1 1 
ATOM   2998  N ND2 . ASN B 2 60  ? -22.771 -8.480  -41.040  1.00 75.43  ? 60  ASN B ND2 1 
ATOM   2999  N N   . THR B 2 61  ? -26.242 -9.297  -42.193  1.00 64.64  ? 61  THR B N   1 
ATOM   3000  C CA  . THR B 2 61  ? -27.244 -8.728  -41.304  1.00 78.62  ? 61  THR B CA  1 
ATOM   3001  C C   . THR B 2 61  ? -26.948 -9.139  -39.870  1.00 70.78  ? 61  THR B C   1 
ATOM   3002  O O   . THR B 2 61  ? -26.610 -10.297 -39.601  1.00 74.90  ? 61  THR B O   1 
ATOM   3003  C CB  . THR B 2 61  ? -28.660 -9.172  -41.693  1.00 81.71  ? 61  THR B CB  1 
ATOM   3004  O OG1 . THR B 2 61  ? -28.704 -10.599 -41.807  1.00 86.26  ? 61  THR B OG1 1 
ATOM   3005  C CG2 . THR B 2 61  ? -29.074 -8.541  -43.018  1.00 69.38  ? 61  THR B CG2 1 
ATOM   3006  N N   . GLN B 2 62  ? -27.070 -8.182  -38.957  1.00 76.57  ? 62  GLN B N   1 
ATOM   3007  C CA  . GLN B 2 62  ? -26.839 -8.409  -37.541  1.00 67.20  ? 62  GLN B CA  1 
ATOM   3008  C C   . GLN B 2 62  ? -28.048 -7.928  -36.756  1.00 57.88  ? 62  GLN B C   1 
ATOM   3009  O O   . GLN B 2 62  ? -28.853 -7.131  -37.245  1.00 66.42  ? 62  GLN B O   1 
ATOM   3010  C CB  . GLN B 2 62  ? -25.582 -7.682  -37.043  1.00 60.01  ? 62  GLN B CB  1 
ATOM   3011  C CG  . GLN B 2 62  ? -24.556 -7.394  -38.118  1.00 63.74  ? 62  GLN B CG  1 
ATOM   3012  C CD  . GLN B 2 62  ? -23.385 -6.590  -37.596  1.00 68.98  ? 62  GLN B CD  1 
ATOM   3013  O OE1 . GLN B 2 62  ? -23.026 -6.686  -36.423  1.00 65.93  ? 62  GLN B OE1 1 
ATOM   3014  N NE2 . GLN B 2 62  ? -22.785 -5.785  -38.465  1.00 73.50  ? 62  GLN B NE2 1 
ATOM   3015  N N   . PHE B 2 63  ? -28.169 -8.423  -35.528  1.00 52.74  ? 63  PHE B N   1 
ATOM   3016  C CA  . PHE B 2 63  ? -29.220 -7.949  -34.640  1.00 46.74  ? 63  PHE B CA  1 
ATOM   3017  C C   . PHE B 2 63  ? -28.986 -6.484  -34.296  1.00 53.85  ? 63  PHE B C   1 
ATOM   3018  O O   . PHE B 2 63  ? -27.880 -6.094  -33.908  1.00 59.30  ? 63  PHE B O   1 
ATOM   3019  C CB  . PHE B 2 63  ? -29.260 -8.792  -33.364  1.00 44.84  ? 63  PHE B CB  1 
ATOM   3020  C CG  . PHE B 2 63  ? -30.307 -8.350  -32.375  1.00 63.24  ? 63  PHE B CG  1 
ATOM   3021  C CD1 . PHE B 2 63  ? -31.599 -8.843  -32.450  1.00 59.16  ? 63  PHE B CD1 1 
ATOM   3022  C CD2 . PHE B 2 63  ? -29.997 -7.446  -31.370  1.00 49.67  ? 63  PHE B CD2 1 
ATOM   3023  C CE1 . PHE B 2 63  ? -32.565 -8.440  -31.545  1.00 63.48  ? 63  PHE B CE1 1 
ATOM   3024  C CE2 . PHE B 2 63  ? -30.961 -7.035  -30.464  1.00 51.04  ? 63  PHE B CE2 1 
ATOM   3025  C CZ  . PHE B 2 63  ? -32.246 -7.535  -30.551  1.00 54.10  ? 63  PHE B CZ  1 
ATOM   3026  N N   . GLU B 2 64  ? -30.028 -5.669  -34.443  1.00 57.45  ? 64  GLU B N   1 
ATOM   3027  C CA  . GLU B 2 64  ? -29.990 -4.282  -34.007  1.00 48.73  ? 64  GLU B CA  1 
ATOM   3028  C C   . GLU B 2 64  ? -31.344 -3.897  -33.438  1.00 56.53  ? 64  GLU B C   1 
ATOM   3029  O O   . GLU B 2 64  ? -32.383 -4.414  -33.857  1.00 53.23  ? 64  GLU B O   1 
ATOM   3030  C CB  . GLU B 2 64  ? -29.616 -3.314  -35.143  1.00 65.94  ? 64  GLU B CB  1 
ATOM   3031  C CG  . GLU B 2 64  ? -28.188 -3.445  -35.665  1.00 70.32  ? 64  GLU B CG  1 
ATOM   3032  C CD  . GLU B 2 64  ? -27.120 -3.139  -34.621  1.00 61.80  ? 64  GLU B CD  1 
ATOM   3033  O OE1 . GLU B 2 64  ? -27.452 -2.712  -33.493  1.00 67.08  ? 64  GLU B OE1 1 
ATOM   3034  O OE2 . GLU B 2 64  ? -25.930 -3.331  -34.940  1.00 64.01  ? 64  GLU B OE2 1 
ATOM   3035  N N   . ALA B 2 65  ? -31.320 -2.980  -32.476  1.00 49.12  ? 65  ALA B N   1 
ATOM   3036  C CA  . ALA B 2 65  ? -32.525 -2.445  -31.854  1.00 47.92  ? 65  ALA B CA  1 
ATOM   3037  C C   . ALA B 2 65  ? -32.556 -0.947  -32.121  1.00 53.18  ? 65  ALA B C   1 
ATOM   3038  O O   . ALA B 2 65  ? -31.729 -0.199  -31.587  1.00 50.29  ? 65  ALA B O   1 
ATOM   3039  C CB  . ALA B 2 65  ? -32.552 -2.747  -30.357  1.00 50.48  ? 65  ALA B CB  1 
ATOM   3040  N N   . VAL B 2 66  ? -33.499 -0.510  -32.948  1.00 55.54  ? 66  VAL B N   1 
ATOM   3041  C CA  . VAL B 2 66  ? -33.602 0.884   -33.357  1.00 60.32  ? 66  VAL B CA  1 
ATOM   3042  C C   . VAL B 2 66  ? -34.801 1.498   -32.648  1.00 61.15  ? 66  VAL B C   1 
ATOM   3043  O O   . VAL B 2 66  ? -35.947 1.090   -32.879  1.00 56.72  ? 66  VAL B O   1 
ATOM   3044  C CB  . VAL B 2 66  ? -33.726 1.023   -34.881  1.00 54.38  ? 66  VAL B CB  1 
ATOM   3045  C CG1 . VAL B 2 66  ? -33.753 2.490   -35.276  1.00 51.58  ? 66  VAL B CG1 1 
ATOM   3046  C CG2 . VAL B 2 66  ? -32.578 0.301   -35.571  1.00 41.60  ? 66  VAL B CG2 1 
ATOM   3047  N N   . GLY B 2 67  ? -34.534 2.474   -31.784  1.00 62.41  ? 67  GLY B N   1 
ATOM   3048  C CA  . GLY B 2 67  ? -35.581 3.197   -31.093  1.00 44.98  ? 67  GLY B CA  1 
ATOM   3049  C C   . GLY B 2 67  ? -35.253 4.669   -30.956  1.00 54.54  ? 67  GLY B C   1 
ATOM   3050  O O   . GLY B 2 67  ? -34.302 5.157   -31.573  1.00 59.24  ? 67  GLY B O   1 
ATOM   3051  N N   . ARG B 2 68  ? -36.035 5.388   -30.155  1.00 53.14  ? 68  ARG B N   1 
ATOM   3052  C CA  . ARG B 2 68  ? -35.822 6.808   -29.877  1.00 47.82  ? 68  ARG B CA  1 
ATOM   3053  C C   . ARG B 2 68  ? -35.692 6.947   -28.362  1.00 59.90  ? 68  ARG B C   1 
ATOM   3054  O O   . ARG B 2 68  ? -36.686 7.130   -27.655  1.00 52.01  ? 68  ARG B O   1 
ATOM   3055  C CB  . ARG B 2 68  ? -36.963 7.659   -30.435  1.00 44.40  ? 68  ARG B CB  1 
ATOM   3056  C CG  . ARG B 2 68  ? -37.009 7.722   -31.957  1.00 58.90  ? 68  ARG B CG  1 
ATOM   3057  C CD  . ARG B 2 68  ? -35.801 8.461   -32.518  1.00 50.93  ? 68  ARG B CD  1 
ATOM   3058  N NE  . ARG B 2 68  ? -35.874 8.620   -33.966  1.00 60.51  ? 68  ARG B NE  1 
ATOM   3059  C CZ  . ARG B 2 68  ? -35.302 7.805   -34.841  1.00 59.17  ? 68  ARG B CZ  1 
ATOM   3060  N NH1 . ARG B 2 68  ? -34.595 6.757   -34.451  1.00 58.25  ? 68  ARG B NH1 1 
ATOM   3061  N NH2 . ARG B 2 68  ? -35.440 8.048   -36.141  1.00 63.91  ? 68  ARG B NH2 1 
ATOM   3062  N N   . GLU B 2 69  ? -34.459 6.861   -27.865  1.00 54.33  ? 69  GLU B N   1 
ATOM   3063  C CA  . GLU B 2 69  ? -34.210 6.726   -26.436  1.00 54.90  ? 69  GLU B CA  1 
ATOM   3064  C C   . GLU B 2 69  ? -33.632 7.982   -25.794  1.00 52.42  ? 69  GLU B C   1 
ATOM   3065  O O   . GLU B 2 69  ? -33.147 7.910   -24.660  1.00 53.95  ? 69  GLU B O   1 
ATOM   3066  C CB  . GLU B 2 69  ? -33.285 5.534   -26.183  1.00 63.78  ? 69  GLU B CB  1 
ATOM   3067  C CG  . GLU B 2 69  ? -33.800 4.231   -26.776  1.00 71.83  ? 69  GLU B CG  1 
ATOM   3068  C CD  . GLU B 2 69  ? -33.397 3.015   -25.963  1.00 84.64  ? 69  GLU B CD  1 
ATOM   3069  O OE1 . GLU B 2 69  ? -32.393 2.362   -26.320  1.00 90.21  ? 69  GLU B OE1 1 
ATOM   3070  O OE2 . GLU B 2 69  ? -34.086 2.713   -24.965  1.00 81.47  ? 69  GLU B OE2 1 
ATOM   3071  N N   . PHE B 2 70  ? -33.675 9.126   -26.473  1.00 54.45  ? 70  PHE B N   1 
ATOM   3072  C CA  . PHE B 2 70  ? -33.119 10.367  -25.950  1.00 51.25  ? 70  PHE B CA  1 
ATOM   3073  C C   . PHE B 2 70  ? -34.228 11.385  -25.708  1.00 50.11  ? 70  PHE B C   1 
ATOM   3074  O O   . PHE B 2 70  ? -35.117 11.562  -26.548  1.00 64.65  ? 70  PHE B O   1 
ATOM   3075  C CB  . PHE B 2 70  ? -32.065 10.937  -26.906  1.00 51.71  ? 70  PHE B CB  1 
ATOM   3076  C CG  . PHE B 2 70  ? -30.887 10.025  -27.115  1.00 47.04  ? 70  PHE B CG  1 
ATOM   3077  C CD1 . PHE B 2 70  ? -29.905 9.908   -26.145  1.00 36.39  ? 70  PHE B CD1 1 
ATOM   3078  C CD2 . PHE B 2 70  ? -30.767 9.279   -28.276  1.00 45.43  ? 70  PHE B CD2 1 
ATOM   3079  C CE1 . PHE B 2 70  ? -28.824 9.066   -26.328  1.00 41.23  ? 70  PHE B CE1 1 
ATOM   3080  C CE2 . PHE B 2 70  ? -29.688 8.432   -28.466  1.00 36.48  ? 70  PHE B CE2 1 
ATOM   3081  C CZ  . PHE B 2 70  ? -28.715 8.326   -27.489  1.00 45.80  ? 70  PHE B CZ  1 
ATOM   3082  N N   . ASN B 2 71  ? -34.173 12.051  -24.554  1.00 53.05  ? 71  ASN B N   1 
ATOM   3083  C CA  . ASN B 2 71  ? -35.232 12.961  -24.138  1.00 59.77  ? 71  ASN B CA  1 
ATOM   3084  C C   . ASN B 2 71  ? -35.029 14.337  -24.775  1.00 56.95  ? 71  ASN B C   1 
ATOM   3085  O O   . ASN B 2 71  ? -34.172 14.530  -25.643  1.00 57.20  ? 71  ASN B O   1 
ATOM   3086  C CB  . ASN B 2 71  ? -35.303 13.031  -22.612  1.00 55.20  ? 71  ASN B CB  1 
ATOM   3087  C CG  . ASN B 2 71  ? -34.003 13.501  -21.973  1.00 67.23  ? 71  ASN B CG  1 
ATOM   3088  O OD1 . ASN B 2 71  ? -33.348 14.428  -22.455  1.00 53.86  ? 71  ASN B OD1 1 
ATOM   3089  N ND2 . ASN B 2 71  ? -33.629 12.861  -20.869  1.00 59.05  ? 71  ASN B ND2 1 
ATOM   3090  N N   . ASN B 2 72  ? -35.819 15.319  -24.334  1.00 60.08  ? 72  ASN B N   1 
ATOM   3091  C CA  . ASN B 2 72  ? -35.855 16.631  -24.970  1.00 61.40  ? 72  ASN B CA  1 
ATOM   3092  C C   . ASN B 2 72  ? -34.675 17.522  -24.598  1.00 66.70  ? 72  ASN B C   1 
ATOM   3093  O O   . ASN B 2 72  ? -34.517 18.587  -25.202  1.00 68.87  ? 72  ASN B O   1 
ATOM   3094  C CB  . ASN B 2 72  ? -37.167 17.339  -24.623  1.00 70.17  ? 72  ASN B CB  1 
ATOM   3095  C CG  . ASN B 2 72  ? -37.248 17.728  -23.161  1.00 92.33  ? 72  ASN B CG  1 
ATOM   3096  O OD1 . ASN B 2 72  ? -37.277 16.872  -22.278  1.00 93.98  ? 72  ASN B OD1 1 
ATOM   3097  N ND2 . ASN B 2 72  ? -37.292 19.030  -22.898  1.00 97.75  ? 72  ASN B ND2 1 
ATOM   3098  N N   . LEU B 2 73  ? -33.859 17.131  -23.622  1.00 63.75  ? 73  LEU B N   1 
ATOM   3099  C CA  . LEU B 2 73  ? -32.598 17.806  -23.346  1.00 58.53  ? 73  LEU B CA  1 
ATOM   3100  C C   . LEU B 2 73  ? -31.406 17.048  -23.914  1.00 49.24  ? 73  LEU B C   1 
ATOM   3101  O O   . LEU B 2 73  ? -30.264 17.324  -23.535  1.00 49.65  ? 73  LEU B O   1 
ATOM   3102  C CB  . LEU B 2 73  ? -32.423 18.024  -21.842  1.00 55.35  ? 73  LEU B CB  1 
ATOM   3103  C CG  . LEU B 2 73  ? -33.321 19.104  -21.234  1.00 75.80  ? 73  LEU B CG  1 
ATOM   3104  C CD1 . LEU B 2 73  ? -32.957 19.362  -19.781  1.00 62.30  ? 73  LEU B CD1 1 
ATOM   3105  C CD2 . LEU B 2 73  ? -33.244 20.390  -22.051  1.00 66.48  ? 73  LEU B CD2 1 
ATOM   3106  N N   . GLU B 2 74  ? -31.651 16.088  -24.803  1.00 45.25  ? 74  GLU B N   1 
ATOM   3107  C CA  . GLU B 2 74  ? -30.603 15.338  -25.481  1.00 49.29  ? 74  GLU B CA  1 
ATOM   3108  C C   . GLU B 2 74  ? -30.817 15.373  -26.990  1.00 49.07  ? 74  GLU B C   1 
ATOM   3109  O O   . GLU B 2 74  ? -30.489 14.414  -27.693  1.00 43.84  ? 74  GLU B O   1 
ATOM   3110  C CB  . GLU B 2 74  ? -30.547 13.897  -24.971  1.00 45.02  ? 74  GLU B CB  1 
ATOM   3111  C CG  . GLU B 2 74  ? -30.270 13.777  -23.479  1.00 51.79  ? 74  GLU B CG  1 
ATOM   3112  C CD  . GLU B 2 74  ? -30.470 12.364  -22.950  1.00 58.00  ? 74  GLU B CD  1 
ATOM   3113  O OE1 . GLU B 2 74  ? -31.446 11.699  -23.358  1.00 52.00  ? 74  GLU B OE1 1 
ATOM   3114  O OE2 . GLU B 2 74  ? -29.646 11.916  -22.125  1.00 61.27  ? 74  GLU B OE2 1 
ATOM   3115  N N   . ARG B 2 75  ? -31.368 16.480  -27.499  1.00 46.60  ? 75  ARG B N   1 
ATOM   3116  C CA  . ARG B 2 75  ? -31.694 16.574  -28.919  1.00 54.90  ? 75  ARG B CA  1 
ATOM   3117  C C   . ARG B 2 75  ? -30.446 16.588  -29.795  1.00 49.68  ? 75  ARG B C   1 
ATOM   3118  O O   . ARG B 2 75  ? -30.512 16.188  -30.963  1.00 48.21  ? 75  ARG B O   1 
ATOM   3119  C CB  . ARG B 2 75  ? -32.542 17.819  -29.181  1.00 49.86  ? 75  ARG B CB  1 
ATOM   3120  C CG  . ARG B 2 75  ? -33.943 17.754  -28.591  1.00 53.24  ? 75  ARG B CG  1 
ATOM   3121  C CD  . ARG B 2 75  ? -34.813 16.762  -29.348  1.00 71.17  ? 75  ARG B CD  1 
ATOM   3122  N NE  . ARG B 2 75  ? -36.166 16.682  -28.809  1.00 84.63  ? 75  ARG B NE  1 
ATOM   3123  C CZ  . ARG B 2 75  ? -36.709 15.586  -28.294  1.00 96.09  ? 75  ARG B CZ  1 
ATOM   3124  N NH1 . ARG B 2 75  ? -36.048 14.440  -28.251  1.00 83.76  ? 75  ARG B NH1 1 
ATOM   3125  N NH2 . ARG B 2 75  ? -37.950 15.640  -27.816  1.00 79.35  ? 75  ARG B NH2 1 
ATOM   3126  N N   . ARG B 2 76  ? -29.312 17.057  -29.266  1.00 45.45  ? 76  ARG B N   1 
ATOM   3127  C CA  . ARG B 2 76  ? -28.074 17.032  -30.042  1.00 40.24  ? 76  ARG B CA  1 
ATOM   3128  C C   . ARG B 2 76  ? -27.624 15.604  -30.325  1.00 45.43  ? 76  ARG B C   1 
ATOM   3129  O O   . ARG B 2 76  ? -27.213 15.288  -31.448  1.00 56.20  ? 76  ARG B O   1 
ATOM   3130  C CB  . ARG B 2 76  ? -26.977 17.803  -29.310  1.00 38.64  ? 76  ARG B CB  1 
ATOM   3131  C CG  . ARG B 2 76  ? -27.214 19.303  -29.220  1.00 47.63  ? 76  ARG B CG  1 
ATOM   3132  C CD  . ARG B 2 76  ? -26.207 19.935  -28.277  1.00 40.06  ? 76  ARG B CD  1 
ATOM   3133  N NE  . ARG B 2 76  ? -26.283 19.340  -26.948  1.00 45.00  ? 76  ARG B NE  1 
ATOM   3134  C CZ  . ARG B 2 76  ? -25.257 19.225  -26.116  1.00 44.13  ? 76  ARG B CZ  1 
ATOM   3135  N NH1 . ARG B 2 76  ? -24.045 19.633  -26.454  1.00 44.54  ? 76  ARG B NH1 1 
ATOM   3136  N NH2 . ARG B 2 76  ? -25.450 18.679  -24.919  1.00 40.19  ? 76  ARG B NH2 1 
ATOM   3137  N N   . ILE B 2 77  ? -27.685 14.729  -29.319  1.00 47.40  ? 77  ILE B N   1 
ATOM   3138  C CA  . ILE B 2 77  ? -27.365 13.323  -29.542  1.00 48.38  ? 77  ILE B CA  1 
ATOM   3139  C C   . ILE B 2 77  ? -28.409 12.682  -30.446  1.00 43.73  ? 77  ILE B C   1 
ATOM   3140  O O   . ILE B 2 77  ? -28.081 11.879  -31.328  1.00 56.01  ? 77  ILE B O   1 
ATOM   3141  C CB  . ILE B 2 77  ? -27.243 12.581  -28.199  1.00 52.36  ? 77  ILE B CB  1 
ATOM   3142  C CG1 . ILE B 2 77  ? -26.225 13.278  -27.296  1.00 57.26  ? 77  ILE B CG1 1 
ATOM   3143  C CG2 . ILE B 2 77  ? -26.837 11.136  -28.429  1.00 53.46  ? 77  ILE B CG2 1 
ATOM   3144  C CD1 . ILE B 2 77  ? -26.178 12.721  -25.887  1.00 56.74  ? 77  ILE B CD1 1 
ATOM   3145  N N   . GLU B 2 78  ? -29.681 13.026  -30.242  1.00 47.63  ? 78  GLU B N   1 
ATOM   3146  C CA  . GLU B 2 78  ? -30.734 12.538  -31.126  1.00 60.40  ? 78  GLU B CA  1 
ATOM   3147  C C   . GLU B 2 78  ? -30.492 12.987  -32.561  1.00 45.88  ? 78  GLU B C   1 
ATOM   3148  O O   . GLU B 2 78  ? -30.690 12.211  -33.504  1.00 54.73  ? 78  GLU B O   1 
ATOM   3149  C CB  . GLU B 2 78  ? -32.095 13.023  -30.627  1.00 58.84  ? 78  GLU B CB  1 
ATOM   3150  C CG  . GLU B 2 78  ? -33.246 12.747  -31.577  1.00 70.07  ? 78  GLU B CG  1 
ATOM   3151  C CD  . GLU B 2 78  ? -34.569 13.272  -31.052  1.00 88.13  ? 78  GLU B CD  1 
ATOM   3152  O OE1 . GLU B 2 78  ? -35.186 12.597  -30.199  1.00 99.00  ? 78  GLU B OE1 1 
ATOM   3153  O OE2 . GLU B 2 78  ? -34.987 14.367  -31.485  1.00 83.19  ? 78  GLU B OE2 1 
ATOM   3154  N N   . ASN B 2 79  ? -30.058 14.236  -32.746  1.00 50.47  ? 79  ASN B N   1 
ATOM   3155  C CA  . ASN B 2 79  ? -29.708 14.708  -34.081  1.00 54.95  ? 79  ASN B CA  1 
ATOM   3156  C C   . ASN B 2 79  ? -28.512 13.944  -34.635  1.00 54.42  ? 79  ASN B C   1 
ATOM   3157  O O   . ASN B 2 79  ? -28.449 13.660  -35.837  1.00 52.74  ? 79  ASN B O   1 
ATOM   3158  C CB  . ASN B 2 79  ? -29.419 16.209  -34.050  1.00 43.20  ? 79  ASN B CB  1 
ATOM   3159  C CG  . ASN B 2 79  ? -29.194 16.786  -35.432  1.00 63.16  ? 79  ASN B CG  1 
ATOM   3160  O OD1 . ASN B 2 79  ? -29.934 16.483  -36.370  1.00 54.61  ? 79  ASN B OD1 1 
ATOM   3161  N ND2 . ASN B 2 79  ? -28.163 17.613  -35.570  1.00 64.55  ? 79  ASN B ND2 1 
ATOM   3162  N N   . LEU B 2 80  ? -27.548 13.608  -33.772  1.00 51.77  ? 80  LEU B N   1 
ATOM   3163  C CA  . LEU B 2 80  ? -26.419 12.791  -34.204  1.00 57.71  ? 80  LEU B CA  1 
ATOM   3164  C C   . LEU B 2 80  ? -26.886 11.425  -34.692  1.00 58.26  ? 80  LEU B C   1 
ATOM   3165  O O   . LEU B 2 80  ? -26.405 10.925  -35.715  1.00 44.31  ? 80  LEU B O   1 
ATOM   3166  C CB  . LEU B 2 80  ? -25.413 12.643  -33.062  1.00 44.29  ? 80  LEU B CB  1 
ATOM   3167  C CG  . LEU B 2 80  ? -24.245 11.672  -33.251  1.00 67.46  ? 80  LEU B CG  1 
ATOM   3168  C CD1 . LEU B 2 80  ? -23.473 11.983  -34.521  1.00 49.82  ? 80  LEU B CD1 1 
ATOM   3169  C CD2 . LEU B 2 80  ? -23.322 11.712  -32.042  1.00 54.44  ? 80  LEU B CD2 1 
ATOM   3170  N N   . ASN B 2 81  ? -27.826 10.807  -33.974  1.00 51.03  ? 81  ASN B N   1 
ATOM   3171  C CA  . ASN B 2 81  ? -28.398 9.550   -34.442  1.00 50.48  ? 81  ASN B CA  1 
ATOM   3172  C C   . ASN B 2 81  ? -29.169 9.746   -35.741  1.00 61.05  ? 81  ASN B C   1 
ATOM   3173  O O   . ASN B 2 81  ? -29.143 8.880   -36.624  1.00 53.43  ? 81  ASN B O   1 
ATOM   3174  C CB  . ASN B 2 81  ? -29.304 8.948   -33.368  1.00 54.98  ? 81  ASN B CB  1 
ATOM   3175  C CG  . ASN B 2 81  ? -30.065 7.733   -33.866  1.00 56.30  ? 81  ASN B CG  1 
ATOM   3176  O OD1 . ASN B 2 81  ? -29.521 6.633   -33.936  1.00 57.25  ? 81  ASN B OD1 1 
ATOM   3177  N ND2 . ASN B 2 81  ? -31.331 7.929   -34.218  1.00 56.95  ? 81  ASN B ND2 1 
ATOM   3178  N N   . LYS B 2 82  ? -29.867 10.878  -35.874  1.00 54.72  ? 82  LYS B N   1 
ATOM   3179  C CA  . LYS B 2 82  ? -30.617 11.147  -37.097  1.00 55.81  ? 82  LYS B CA  1 
ATOM   3180  C C   . LYS B 2 82  ? -29.694 11.242  -38.306  1.00 60.91  ? 82  LYS B C   1 
ATOM   3181  O O   . LYS B 2 82  ? -29.999 10.696  -39.373  1.00 51.79  ? 82  LYS B O   1 
ATOM   3182  C CB  . LYS B 2 82  ? -31.430 12.432  -36.943  1.00 51.90  ? 82  LYS B CB  1 
ATOM   3183  C CG  . LYS B 2 82  ? -32.032 12.935  -38.245  1.00 54.56  ? 82  LYS B CG  1 
ATOM   3184  C CD  . LYS B 2 82  ? -32.727 14.271  -38.060  1.00 61.16  ? 82  LYS B CD  1 
ATOM   3185  C CE  . LYS B 2 82  ? -33.113 14.876  -39.401  1.00 75.38  ? 82  LYS B CE  1 
ATOM   3186  N NZ  . LYS B 2 82  ? -33.936 13.937  -40.215  1.00 60.95  ? 82  LYS B NZ  1 
ATOM   3187  N N   . LYS B 2 83  ? -28.559 11.931  -38.160  1.00 58.83  ? 83  LYS B N   1 
ATOM   3188  C CA  . LYS B 2 83  ? -27.603 12.011  -39.259  1.00 53.82  ? 83  LYS B CA  1 
ATOM   3189  C C   . LYS B 2 83  ? -27.013 10.645  -39.584  1.00 55.08  ? 83  LYS B C   1 
ATOM   3190  O O   . LYS B 2 83  ? -26.668 10.378  -40.741  1.00 61.77  ? 83  LYS B O   1 
ATOM   3191  C CB  . LYS B 2 83  ? -26.491 13.007  -38.924  1.00 45.13  ? 83  LYS B CB  1 
ATOM   3192  C CG  . LYS B 2 83  ? -26.933 14.463  -38.958  1.00 55.22  ? 83  LYS B CG  1 
ATOM   3193  C CD  . LYS B 2 83  ? -25.775 15.405  -38.671  1.00 52.89  ? 83  LYS B CD  1 
ATOM   3194  C CE  . LYS B 2 83  ? -25.450 15.447  -37.187  1.00 57.83  ? 83  LYS B CE  1 
ATOM   3195  N NZ  . LYS B 2 83  ? -24.141 16.107  -36.925  1.00 66.75  ? 83  LYS B NZ  1 
ATOM   3196  N N   . MET B 2 84  ? -26.883 9.773   -38.584  1.00 54.86  ? 84  MET B N   1 
ATOM   3197  C CA  . MET B 2 84  ? -26.366 8.432   -38.837  1.00 53.45  ? 84  MET B CA  1 
ATOM   3198  C C   . MET B 2 84  ? -27.372 7.588   -39.611  1.00 55.27  ? 84  MET B C   1 
ATOM   3199  O O   . MET B 2 84  ? -27.023 6.954   -40.614  1.00 56.80  ? 84  MET B O   1 
ATOM   3200  C CB  . MET B 2 84  ? -26.000 7.755   -37.518  1.00 46.50  ? 84  MET B CB  1 
ATOM   3201  C CG  . MET B 2 84  ? -25.171 6.500   -37.687  1.00 54.67  ? 84  MET B CG  1 
ATOM   3202  S SD  . MET B 2 84  ? -25.411 5.342   -36.333  1.00 72.68  ? 84  MET B SD  1 
ATOM   3203  C CE  . MET B 2 84  ? -27.156 4.984   -36.507  1.00 69.14  ? 84  MET B CE  1 
ATOM   3204  N N   . GLU B 2 85  ? -28.630 7.569   -39.161  1.00 54.55  ? 85  GLU B N   1 
ATOM   3205  C CA  . GLU B 2 85  ? -29.645 6.770   -39.842  1.00 66.48  ? 85  GLU B CA  1 
ATOM   3206  C C   . GLU B 2 85  ? -29.882 7.272   -41.259  1.00 55.84  ? 85  GLU B C   1 
ATOM   3207  O O   . GLU B 2 85  ? -29.999 6.475   -42.197  1.00 58.92  ? 85  GLU B O   1 
ATOM   3208  C CB  . GLU B 2 85  ? -30.951 6.777   -39.045  1.00 59.02  ? 85  GLU B CB  1 
ATOM   3209  C CG  . GLU B 2 85  ? -30.909 5.958   -37.765  1.00 71.09  ? 85  GLU B CG  1 
ATOM   3210  C CD  . GLU B 2 85  ? -32.267 5.854   -37.090  1.00 73.32  ? 85  GLU B CD  1 
ATOM   3211  O OE1 . GLU B 2 85  ? -33.293 6.090   -37.764  1.00 67.94  ? 85  GLU B OE1 1 
ATOM   3212  O OE2 . GLU B 2 85  ? -32.308 5.535   -35.882  1.00 64.45  ? 85  GLU B OE2 1 
ATOM   3213  N N   . ASP B 2 86  ? -29.955 8.594   -41.435  1.00 48.14  ? 86  ASP B N   1 
ATOM   3214  C CA  . ASP B 2 86  ? -30.139 9.156   -42.768  1.00 51.88  ? 86  ASP B CA  1 
ATOM   3215  C C   . ASP B 2 86  ? -28.941 8.862   -43.662  1.00 59.66  ? 86  ASP B C   1 
ATOM   3216  O O   . ASP B 2 86  ? -29.106 8.580   -44.855  1.00 54.79  ? 86  ASP B O   1 
ATOM   3217  C CB  . ASP B 2 86  ? -30.388 10.660  -42.673  1.00 51.16  ? 86  ASP B CB  1 
ATOM   3218  C CG  . ASP B 2 86  ? -31.707 10.991  -41.996  1.00 62.66  ? 86  ASP B CG  1 
ATOM   3219  O OD1 . ASP B 2 86  ? -32.433 10.049  -41.610  1.00 64.64  ? 86  ASP B OD1 1 
ATOM   3220  O OD2 . ASP B 2 86  ? -32.021 12.191  -41.853  1.00 58.52  ? 86  ASP B OD2 1 
ATOM   3221  N N   . GLY B 2 87  ? -27.730 8.922   -43.104  1.00 57.16  ? 87  GLY B N   1 
ATOM   3222  C CA  . GLY B 2 87  ? -26.546 8.640   -43.899  1.00 48.46  ? 87  GLY B CA  1 
ATOM   3223  C C   . GLY B 2 87  ? -26.518 7.219   -44.429  1.00 52.94  ? 87  GLY B C   1 
ATOM   3224  O O   . GLY B 2 87  ? -26.190 6.988   -45.594  1.00 57.21  ? 87  GLY B O   1 
ATOM   3225  N N   . PHE B 2 88  ? -26.861 6.246   -43.582  1.00 48.52  ? 88  PHE B N   1 
ATOM   3226  C CA  . PHE B 2 88  ? -26.895 4.861   -44.040  1.00 51.56  ? 88  PHE B CA  1 
ATOM   3227  C C   . PHE B 2 88  ? -28.041 4.618   -45.012  1.00 53.13  ? 88  PHE B C   1 
ATOM   3228  O O   . PHE B 2 88  ? -27.909 3.796   -45.925  1.00 53.33  ? 88  PHE B O   1 
ATOM   3229  C CB  . PHE B 2 88  ? -26.987 3.908   -42.850  1.00 38.34  ? 88  PHE B CB  1 
ATOM   3230  C CG  . PHE B 2 88  ? -25.696 3.762   -42.099  1.00 50.00  ? 88  PHE B CG  1 
ATOM   3231  C CD1 . PHE B 2 88  ? -24.582 3.219   -42.717  1.00 47.73  ? 88  PHE B CD1 1 
ATOM   3232  C CD2 . PHE B 2 88  ? -25.594 4.166   -40.780  1.00 52.20  ? 88  PHE B CD2 1 
ATOM   3233  C CE1 . PHE B 2 88  ? -23.388 3.083   -42.034  1.00 54.84  ? 88  PHE B CE1 1 
ATOM   3234  C CE2 . PHE B 2 88  ? -24.402 4.031   -40.090  1.00 57.50  ? 88  PHE B CE2 1 
ATOM   3235  C CZ  . PHE B 2 88  ? -23.298 3.488   -40.719  1.00 54.77  ? 88  PHE B CZ  1 
ATOM   3236  N N   . LEU B 2 89  ? -29.167 5.311   -44.832  1.00 54.83  ? 89  LEU B N   1 
ATOM   3237  C CA  . LEU B 2 89  ? -30.248 5.214   -45.807  1.00 54.14  ? 89  LEU B CA  1 
ATOM   3238  C C   . LEU B 2 89  ? -29.788 5.691   -47.178  1.00 61.44  ? 89  LEU B C   1 
ATOM   3239  O O   . LEU B 2 89  ? -30.071 5.048   -48.195  1.00 55.97  ? 89  LEU B O   1 
ATOM   3240  C CB  . LEU B 2 89  ? -31.455 6.028   -45.340  1.00 49.40  ? 89  LEU B CB  1 
ATOM   3241  C CG  . LEU B 2 89  ? -32.626 6.089   -46.327  1.00 61.63  ? 89  LEU B CG  1 
ATOM   3242  C CD1 . LEU B 2 89  ? -33.500 4.862   -46.194  1.00 53.53  ? 89  LEU B CD1 1 
ATOM   3243  C CD2 . LEU B 2 89  ? -33.447 7.350   -46.135  1.00 55.40  ? 89  LEU B CD2 1 
ATOM   3244  N N   . ASP B 2 90  ? -29.073 6.818   -47.222  1.00 60.36  ? 90  ASP B N   1 
ATOM   3245  C CA  . ASP B 2 90  ? -28.579 7.340   -48.492  1.00 58.60  ? 90  ASP B CA  1 
ATOM   3246  C C   . ASP B 2 90  ? -27.552 6.404   -49.118  1.00 69.68  ? 90  ASP B C   1 
ATOM   3247  O O   . ASP B 2 90  ? -27.556 6.197   -50.337  1.00 64.53  ? 90  ASP B O   1 
ATOM   3248  C CB  . ASP B 2 90  ? -27.986 8.733   -48.286  1.00 53.12  ? 90  ASP B CB  1 
ATOM   3249  C CG  . ASP B 2 90  ? -29.011 9.734   -47.788  1.00 73.97  ? 90  ASP B CG  1 
ATOM   3250  O OD1 . ASP B 2 90  ? -30.212 9.390   -47.754  1.00 74.06  ? 90  ASP B OD1 1 
ATOM   3251  O OD2 . ASP B 2 90  ? -28.616 10.863  -47.427  1.00 82.39  ? 90  ASP B OD2 1 
ATOM   3252  N N   . VAL B 2 91  ? -26.659 5.836   -48.304  1.00 63.23  ? 91  VAL B N   1 
ATOM   3253  C CA  . VAL B 2 91  ? -25.658 4.911   -48.832  1.00 67.26  ? 91  VAL B CA  1 
ATOM   3254  C C   . VAL B 2 91  ? -26.335 3.682   -49.426  1.00 69.64  ? 91  VAL B C   1 
ATOM   3255  O O   . VAL B 2 91  ? -26.069 3.295   -50.570  1.00 61.75  ? 91  VAL B O   1 
ATOM   3256  C CB  . VAL B 2 91  ? -24.651 4.521   -47.735  1.00 58.07  ? 91  VAL B CB  1 
ATOM   3257  C CG1 . VAL B 2 91  ? -23.791 3.357   -48.200  1.00 44.10  ? 91  VAL B CG1 1 
ATOM   3258  C CG2 . VAL B 2 91  ? -23.780 5.708   -47.362  1.00 45.73  ? 91  VAL B CG2 1 
ATOM   3259  N N   . TRP B 2 92  ? -27.235 3.061   -48.661  1.00 63.45  ? 92  TRP B N   1 
ATOM   3260  C CA  . TRP B 2 92  ? -27.871 1.832   -49.122  1.00 61.74  ? 92  TRP B CA  1 
ATOM   3261  C C   . TRP B 2 92  ? -28.788 2.085   -50.313  1.00 60.23  ? 92  TRP B C   1 
ATOM   3262  O O   . TRP B 2 92  ? -28.857 1.260   -51.231  1.00 53.81  ? 92  TRP B O   1 
ATOM   3263  C CB  . TRP B 2 92  ? -28.639 1.176   -47.976  1.00 42.17  ? 92  TRP B CB  1 
ATOM   3264  C CG  . TRP B 2 92  ? -27.756 0.488   -46.984  1.00 58.09  ? 92  TRP B CG  1 
ATOM   3265  C CD1 . TRP B 2 92  ? -27.658 0.755   -45.649  1.00 53.75  ? 92  TRP B CD1 1 
ATOM   3266  C CD2 . TRP B 2 92  ? -26.837 -0.579  -47.249  1.00 58.70  ? 92  TRP B CD2 1 
ATOM   3267  N NE1 . TRP B 2 92  ? -26.740 -0.084  -45.065  1.00 63.34  ? 92  TRP B NE1 1 
ATOM   3268  C CE2 . TRP B 2 92  ? -26.221 -0.912  -46.025  1.00 60.59  ? 92  TRP B CE2 1 
ATOM   3269  C CE3 . TRP B 2 92  ? -26.477 -1.287  -48.401  1.00 64.98  ? 92  TRP B CE3 1 
ATOM   3270  C CZ2 . TRP B 2 92  ? -25.264 -1.921  -45.921  1.00 61.16  ? 92  TRP B CZ2 1 
ATOM   3271  C CZ3 . TRP B 2 92  ? -25.526 -2.288  -48.295  1.00 64.38  ? 92  TRP B CZ3 1 
ATOM   3272  C CH2 . TRP B 2 92  ? -24.930 -2.595  -47.064  1.00 64.35  ? 92  TRP B CH2 1 
ATOM   3273  N N   . THR B 2 93  ? -29.509 3.208   -50.313  1.00 56.95  ? 93  THR B N   1 
ATOM   3274  C CA  . THR B 2 93  ? -30.399 3.508   -51.430  1.00 63.14  ? 93  THR B CA  1 
ATOM   3275  C C   . THR B 2 93  ? -29.612 3.706   -52.720  1.00 58.21  ? 93  THR B C   1 
ATOM   3276  O O   . THR B 2 93  ? -29.953 3.136   -53.762  1.00 67.51  ? 93  THR B O   1 
ATOM   3277  C CB  . THR B 2 93  ? -31.241 4.747   -51.118  1.00 65.38  ? 93  THR B CB  1 
ATOM   3278  O OG1 . THR B 2 93  ? -32.086 4.481   -49.991  1.00 55.93  ? 93  THR B OG1 1 
ATOM   3279  C CG2 . THR B 2 93  ? -32.101 5.126   -52.316  1.00 58.17  ? 93  THR B CG2 1 
ATOM   3280  N N   . TYR B 2 94  ? -28.543 4.502   -52.664  1.00 63.84  ? 94  TYR B N   1 
ATOM   3281  C CA  . TYR B 2 94  ? -27.750 4.762   -53.862  1.00 55.52  ? 94  TYR B CA  1 
ATOM   3282  C C   . TYR B 2 94  ? -27.070 3.494   -54.364  1.00 67.91  ? 94  TYR B C   1 
ATOM   3283  O O   . TYR B 2 94  ? -27.055 3.225   -55.571  1.00 71.22  ? 94  TYR B O   1 
ATOM   3284  C CB  . TYR B 2 94  ? -26.716 5.850   -53.574  1.00 53.87  ? 94  TYR B CB  1 
ATOM   3285  C CG  . TYR B 2 94  ? -26.008 6.369   -54.804  1.00 79.06  ? 94  TYR B CG  1 
ATOM   3286  C CD1 . TYR B 2 94  ? -26.663 7.195   -55.706  1.00 67.20  ? 94  TYR B CD1 1 
ATOM   3287  C CD2 . TYR B 2 94  ? -24.683 6.041   -55.058  1.00 76.06  ? 94  TYR B CD2 1 
ATOM   3288  C CE1 . TYR B 2 94  ? -26.023 7.677   -56.829  1.00 69.92  ? 94  TYR B CE1 1 
ATOM   3289  C CE2 . TYR B 2 94  ? -24.032 6.519   -56.179  1.00 66.48  ? 94  TYR B CE2 1 
ATOM   3290  C CZ  . TYR B 2 94  ? -24.707 7.337   -57.062  1.00 74.72  ? 94  TYR B CZ  1 
ATOM   3291  O OH  . TYR B 2 94  ? -24.067 7.816   -58.182  1.00 71.48  ? 94  TYR B OH  1 
ATOM   3292  N N   . ASN B 2 95  ? -26.501 2.703   -53.452  1.00 66.08  ? 95  ASN B N   1 
ATOM   3293  C CA  . ASN B 2 95  ? -25.814 1.481   -53.858  1.00 62.91  ? 95  ASN B CA  1 
ATOM   3294  C C   . ASN B 2 95  ? -26.788 0.450   -54.416  1.00 70.55  ? 95  ASN B C   1 
ATOM   3295  O O   . ASN B 2 95  ? -26.469 -0.250  -55.383  1.00 64.95  ? 95  ASN B O   1 
ATOM   3296  C CB  . ASN B 2 95  ? -25.031 0.905   -52.678  1.00 57.86  ? 95  ASN B CB  1 
ATOM   3297  C CG  . ASN B 2 95  ? -23.663 1.547   -52.515  1.00 78.03  ? 95  ASN B CG  1 
ATOM   3298  O OD1 . ASN B 2 95  ? -22.635 0.888   -52.671  1.00 88.29  ? 95  ASN B OD1 1 
ATOM   3299  N ND2 . ASN B 2 95  ? -23.646 2.840   -52.212  1.00 71.23  ? 95  ASN B ND2 1 
ATOM   3300  N N   . ALA B 2 96  ? -27.976 0.334   -53.817  1.00 66.54  ? 96  ALA B N   1 
ATOM   3301  C CA  . ALA B 2 96  ? -28.949 -0.639  -54.304  1.00 66.58  ? 96  ALA B CA  1 
ATOM   3302  C C   . ALA B 2 96  ? -29.492 -0.251  -55.673  1.00 66.41  ? 96  ALA B C   1 
ATOM   3303  O O   . ALA B 2 96  ? -29.611 -1.102  -56.562  1.00 65.58  ? 96  ALA B O   1 
ATOM   3304  C CB  . ALA B 2 96  ? -30.090 -0.794  -53.300  1.00 64.40  ? 96  ALA B CB  1 
ATOM   3305  N N   . GLU B 2 97  ? -29.835 1.027   -55.862  1.00 69.75  ? 97  GLU B N   1 
ATOM   3306  C CA  . GLU B 2 97  ? -30.393 1.461   -57.140  1.00 68.24  ? 97  GLU B CA  1 
ATOM   3307  C C   . GLU B 2 97  ? -29.387 1.292   -58.272  1.00 77.31  ? 97  GLU B C   1 
ATOM   3308  O O   . GLU B 2 97  ? -29.741 0.827   -59.362  1.00 80.66  ? 97  GLU B O   1 
ATOM   3309  C CB  . GLU B 2 97  ? -30.853 2.917   -57.049  1.00 67.62  ? 97  GLU B CB  1 
ATOM   3310  C CG  . GLU B 2 97  ? -32.014 3.161   -56.091  1.00 78.43  ? 97  GLU B CG  1 
ATOM   3311  C CD  . GLU B 2 97  ? -33.358 2.756   -56.664  1.00 90.02  ? 97  GLU B CD  1 
ATOM   3312  O OE1 . GLU B 2 97  ? -33.421 2.419   -57.865  1.00 99.05  ? 97  GLU B OE1 1 
ATOM   3313  O OE2 . GLU B 2 97  ? -34.354 2.781   -55.910  1.00 85.89  ? 97  GLU B OE2 1 
ATOM   3314  N N   . LEU B 2 98  ? -28.126 1.660   -58.032  1.00 69.30  ? 98  LEU B N   1 
ATOM   3315  C CA  . LEU B 2 98  ? -27.118 1.561   -59.082  1.00 69.41  ? 98  LEU B CA  1 
ATOM   3316  C C   . LEU B 2 98  ? -26.699 0.119   -59.332  1.00 69.22  ? 98  LEU B C   1 
ATOM   3317  O O   . LEU B 2 98  ? -26.372 -0.238  -60.469  1.00 76.11  ? 98  LEU B O   1 
ATOM   3318  C CB  . LEU B 2 98  ? -25.904 2.418   -58.729  1.00 63.31  ? 98  LEU B CB  1 
ATOM   3319  C CG  . LEU B 2 98  ? -25.756 3.689   -59.567  1.00 68.34  ? 98  LEU B CG  1 
ATOM   3320  C CD1 . LEU B 2 98  ? -27.051 4.485   -59.573  1.00 76.00  ? 98  LEU B CD1 1 
ATOM   3321  C CD2 . LEU B 2 98  ? -24.611 4.536   -59.048  1.00 80.68  ? 98  LEU B CD2 1 
ATOM   3322  N N   . LEU B 2 99  ? -26.696 -0.718  -58.293  1.00 61.61  ? 99  LEU B N   1 
ATOM   3323  C CA  . LEU B 2 99  ? -26.427 -2.138  -58.493  1.00 70.30  ? 99  LEU B CA  1 
ATOM   3324  C C   . LEU B 2 99  ? -27.474 -2.767  -59.401  1.00 68.49  ? 99  LEU B C   1 
ATOM   3325  O O   . LEU B 2 99  ? -27.148 -3.596  -60.258  1.00 70.29  ? 99  LEU B O   1 
ATOM   3326  C CB  . LEU B 2 99  ? -26.386 -2.862  -57.148  1.00 58.72  ? 99  LEU B CB  1 
ATOM   3327  C CG  . LEU B 2 99  ? -26.235 -4.384  -57.197  1.00 69.02  ? 99  LEU B CG  1 
ATOM   3328  C CD1 . LEU B 2 99  ? -24.818 -4.776  -57.587  1.00 69.89  ? 99  LEU B CD1 1 
ATOM   3329  C CD2 . LEU B 2 99  ? -26.632 -5.015  -55.869  1.00 73.96  ? 99  LEU B CD2 1 
ATOM   3330  N N   . VAL B 2 100 ? -28.741 -2.387  -59.221  1.00 66.25  ? 100 VAL B N   1 
ATOM   3331  C CA  . VAL B 2 100 ? -29.804 -2.891  -60.086  1.00 77.43  ? 100 VAL B CA  1 
ATOM   3332  C C   . VAL B 2 100 ? -29.581 -2.434  -61.523  1.00 79.68  ? 100 VAL B C   1 
ATOM   3333  O O   . VAL B 2 100 ? -29.662 -3.232  -62.464  1.00 78.92  ? 100 VAL B O   1 
ATOM   3334  C CB  . VAL B 2 100 ? -31.179 -2.450  -59.552  1.00 74.48  ? 100 VAL B CB  1 
ATOM   3335  C CG1 . VAL B 2 100 ? -32.196 -2.360  -60.682  1.00 75.59  ? 100 VAL B CG1 1 
ATOM   3336  C CG2 . VAL B 2 100 ? -31.661 -3.418  -58.483  1.00 70.27  ? 100 VAL B CG2 1 
ATOM   3337  N N   . LEU B 2 101 ? -29.283 -1.146  -61.714  1.00 78.06  ? 101 LEU B N   1 
ATOM   3338  C CA  . LEU B 2 101 ? -29.090 -0.627  -63.065  1.00 73.83  ? 101 LEU B CA  1 
ATOM   3339  C C   . LEU B 2 101 ? -27.871 -1.246  -63.737  1.00 77.24  ? 101 LEU B C   1 
ATOM   3340  O O   . LEU B 2 101 ? -27.934 -1.641  -64.906  1.00 88.87  ? 101 LEU B O   1 
ATOM   3341  C CB  . LEU B 2 101 ? -28.960 0.895   -63.035  1.00 67.62  ? 101 LEU B CB  1 
ATOM   3342  C CG  . LEU B 2 101 ? -30.140 1.689   -62.474  1.00 74.92  ? 101 LEU B CG  1 
ATOM   3343  C CD1 . LEU B 2 101 ? -29.974 3.172   -62.771  1.00 68.35  ? 101 LEU B CD1 1 
ATOM   3344  C CD2 . LEU B 2 101 ? -31.457 1.167   -63.026  1.00 76.20  ? 101 LEU B CD2 1 
ATOM   3345  N N   . MET B 2 102 ? -26.752 -1.340  -63.014  1.00 75.01  ? 102 MET B N   1 
ATOM   3346  C CA  . MET B 2 102 ? -25.524 -1.844  -63.620  1.00 79.69  ? 102 MET B CA  1 
ATOM   3347  C C   . MET B 2 102 ? -25.627 -3.328  -63.946  1.00 76.11  ? 102 MET B C   1 
ATOM   3348  O O   . MET B 2 102 ? -25.205 -3.760  -65.024  1.00 88.81  ? 102 MET B O   1 
ATOM   3349  C CB  . MET B 2 102 ? -24.335 -1.574  -62.698  1.00 78.74  ? 102 MET B CB  1 
ATOM   3350  C CG  . MET B 2 102 ? -23.961 -0.102  -62.594  1.00 94.14  ? 102 MET B CG  1 
ATOM   3351  S SD  . MET B 2 102 ? -22.716 0.235   -61.332  1.00 100.29 ? 102 MET B SD  1 
ATOM   3352  C CE  . MET B 2 102 ? -21.315 -0.681  -61.970  1.00 80.27  ? 102 MET B CE  1 
ATOM   3353  N N   . GLU B 2 103 ? -26.181 -4.126  -63.033  1.00 73.08  ? 103 GLU B N   1 
ATOM   3354  C CA  . GLU B 2 103 ? -26.256 -5.560  -63.284  1.00 74.06  ? 103 GLU B CA  1 
ATOM   3355  C C   . GLU B 2 103 ? -27.344 -5.921  -64.287  1.00 83.85  ? 103 GLU B C   1 
ATOM   3356  O O   . GLU B 2 103 ? -27.191 -6.901  -65.023  1.00 86.97  ? 103 GLU B O   1 
ATOM   3357  C CB  . GLU B 2 103 ? -26.458 -6.323  -61.975  1.00 75.89  ? 103 GLU B CB  1 
ATOM   3358  C CG  . GLU B 2 103 ? -25.145 -6.676  -61.297  1.00 83.80  ? 103 GLU B CG  1 
ATOM   3359  C CD  . GLU B 2 103 ? -24.088 -7.134  -62.292  1.00 97.74  ? 103 GLU B CD  1 
ATOM   3360  O OE1 . GLU B 2 103 ? -24.326 -8.133  -63.005  1.00 98.72  ? 103 GLU B OE1 1 
ATOM   3361  O OE2 . GLU B 2 103 ? -23.023 -6.486  -62.372  1.00 93.29  ? 103 GLU B OE2 1 
ATOM   3362  N N   . ASN B 2 104 ? -28.438 -5.155  -64.339  1.00 71.03  ? 104 ASN B N   1 
ATOM   3363  C CA  . ASN B 2 104 ? -29.446 -5.395  -65.368  1.00 76.32  ? 104 ASN B CA  1 
ATOM   3364  C C   . ASN B 2 104 ? -28.870 -5.177  -66.761  1.00 90.09  ? 104 ASN B C   1 
ATOM   3365  O O   . ASN B 2 104 ? -29.149 -5.951  -67.683  1.00 87.40  ? 104 ASN B O   1 
ATOM   3366  C CB  . ASN B 2 104 ? -30.663 -4.498  -65.149  1.00 77.37  ? 104 ASN B CB  1 
ATOM   3367  C CG  . ASN B 2 104 ? -31.621 -5.058  -64.117  1.00 68.53  ? 104 ASN B CG  1 
ATOM   3368  O OD1 . ASN B 2 104 ? -31.525 -6.223  -63.732  1.00 64.63  ? 104 ASN B OD1 1 
ATOM   3369  N ND2 . ASN B 2 104 ? -32.562 -4.232  -63.673  1.00 73.50  ? 104 ASN B ND2 1 
ATOM   3370  N N   . GLU B 2 105 ? -28.068 -4.123  -66.934  1.00 84.71  ? 105 GLU B N   1 
ATOM   3371  C CA  . GLU B 2 105 ? -27.412 -3.899  -68.218  1.00 84.88  ? 105 GLU B CA  1 
ATOM   3372  C C   . GLU B 2 105 ? -26.452 -5.034  -68.551  1.00 88.30  ? 105 GLU B C   1 
ATOM   3373  O O   . GLU B 2 105 ? -26.423 -5.519  -69.689  1.00 88.62  ? 105 GLU B O   1 
ATOM   3374  C CB  . GLU B 2 105 ? -26.678 -2.559  -68.209  1.00 83.86  ? 105 GLU B CB  1 
ATOM   3375  C CG  . GLU B 2 105 ? -25.542 -2.481  -69.214  1.00 97.10  ? 105 GLU B CG  1 
ATOM   3376  C CD  . GLU B 2 105 ? -25.336 -1.083  -69.754  1.00 109.15 ? 105 GLU B CD  1 
ATOM   3377  O OE1 . GLU B 2 105 ? -26.342 -0.364  -69.935  1.00 104.75 ? 105 GLU B OE1 1 
ATOM   3378  O OE2 . GLU B 2 105 ? -24.170 -0.703  -69.996  1.00 108.84 ? 105 GLU B OE2 1 
ATOM   3379  N N   . ARG B 2 106 ? -25.661 -5.474  -67.571  1.00 86.22  ? 106 ARG B N   1 
ATOM   3380  C CA  . ARG B 2 106 ? -24.792 -6.626  -67.784  1.00 88.02  ? 106 ARG B CA  1 
ATOM   3381  C C   . ARG B 2 106 ? -25.601 -7.885  -68.063  1.00 84.40  ? 106 ARG B C   1 
ATOM   3382  O O   . ARG B 2 106 ? -25.173 -8.738  -68.848  1.00 78.36  ? 106 ARG B O   1 
ATOM   3383  C CB  . ARG B 2 106 ? -23.890 -6.833  -66.567  1.00 89.48  ? 106 ARG B CB  1 
ATOM   3384  C CG  . ARG B 2 106 ? -22.919 -5.692  -66.306  1.00 94.92  ? 106 ARG B CG  1 
ATOM   3385  C CD  . ARG B 2 106 ? -21.535 -6.021  -66.835  1.00 101.33 ? 106 ARG B CD  1 
ATOM   3386  N NE  . ARG B 2 106 ? -21.035 -7.270  -66.273  1.00 117.51 ? 106 ARG B NE  1 
ATOM   3387  C CZ  . ARG B 2 106 ? -19.837 -7.780  -66.522  1.00 112.68 ? 106 ARG B CZ  1 
ATOM   3388  N NH1 . ARG B 2 106 ? -18.975 -7.166  -67.317  1.00 107.19 ? 106 ARG B NH1 1 
ATOM   3389  N NH2 . ARG B 2 106 ? -19.494 -8.935  -65.958  1.00 105.99 ? 106 ARG B NH2 1 
ATOM   3390  N N   . THR B 2 107 ? -26.766 -8.022  -67.425  1.00 84.69  ? 107 THR B N   1 
ATOM   3391  C CA  . THR B 2 107 ? -27.605 -9.193  -67.648  1.00 83.06  ? 107 THR B CA  1 
ATOM   3392  C C   . THR B 2 107 ? -28.127 -9.243  -69.079  1.00 87.09  ? 107 THR B C   1 
ATOM   3393  O O   . THR B 2 107 ? -28.132 -10.308 -69.707  1.00 82.75  ? 107 THR B O   1 
ATOM   3394  C CB  . THR B 2 107 ? -28.773 -9.197  -66.665  1.00 73.29  ? 107 THR B CB  1 
ATOM   3395  O OG1 . THR B 2 107 ? -28.333 -8.705  -65.394  1.00 99.67  ? 107 THR B OG1 1 
ATOM   3396  C CG2 . THR B 2 107 ? -29.299 -10.600 -66.491  1.00 78.81  ? 107 THR B CG2 1 
ATOM   3397  N N   . LEU B 2 108 ? -28.578 -8.103  -69.609  1.00 81.23  ? 108 LEU B N   1 
ATOM   3398  C CA  . LEU B 2 108 ? -29.126 -8.088  -70.962  1.00 91.10  ? 108 LEU B CA  1 
ATOM   3399  C C   . LEU B 2 108 ? -28.028 -8.246  -72.006  1.00 89.99  ? 108 LEU B C   1 
ATOM   3400  O O   . LEU B 2 108 ? -28.242 -8.878  -73.047  1.00 86.41  ? 108 LEU B O   1 
ATOM   3401  C CB  . LEU B 2 108 ? -29.920 -6.803  -71.192  1.00 78.64  ? 108 LEU B CB  1 
ATOM   3402  C CG  . LEU B 2 108 ? -31.113 -6.602  -70.254  1.00 69.04  ? 108 LEU B CG  1 
ATOM   3403  C CD1 . LEU B 2 108 ? -31.972 -5.431  -70.707  1.00 70.14  ? 108 LEU B CD1 1 
ATOM   3404  C CD2 . LEU B 2 108 ? -31.944 -7.874  -70.146  1.00 74.81  ? 108 LEU B CD2 1 
ATOM   3405  N N   . ASP B 2 109 ? -26.847 -7.680  -71.749  1.00 85.11  ? 109 ASP B N   1 
ATOM   3406  C CA  . ASP B 2 109 ? -25.711 -7.908  -72.634  1.00 87.23  ? 109 ASP B CA  1 
ATOM   3407  C C   . ASP B 2 109 ? -25.157 -9.320  -72.498  1.00 83.48  ? 109 ASP B C   1 
ATOM   3408  O O   . ASP B 2 109 ? -24.478 -9.798  -73.413  1.00 90.97  ? 109 ASP B O   1 
ATOM   3409  C CB  . ASP B 2 109 ? -24.612 -6.881  -72.357  1.00 89.47  ? 109 ASP B CB  1 
ATOM   3410  C CG  . ASP B 2 109 ? -25.094 -5.453  -72.529  1.00 97.31  ? 109 ASP B CG  1 
ATOM   3411  O OD1 . ASP B 2 109 ? -26.285 -5.261  -72.854  1.00 100.15 ? 109 ASP B OD1 1 
ATOM   3412  O OD2 . ASP B 2 109 ? -24.285 -4.522  -72.336  1.00 92.33  ? 109 ASP B OD2 1 
ATOM   3413  N N   . PHE B 2 110 ? -25.423 -9.989  -71.373  1.00 83.37  ? 110 PHE B N   1 
ATOM   3414  C CA  . PHE B 2 110 ? -25.067 -11.397 -71.238  1.00 73.67  ? 110 PHE B CA  1 
ATOM   3415  C C   . PHE B 2 110 ? -25.836 -12.252 -72.239  1.00 86.95  ? 110 PHE B C   1 
ATOM   3416  O O   . PHE B 2 110 ? -25.272 -13.167 -72.850  1.00 80.16  ? 110 PHE B O   1 
ATOM   3417  C CB  . PHE B 2 110 ? -25.333 -11.859 -69.803  1.00 78.46  ? 110 PHE B CB  1 
ATOM   3418  C CG  . PHE B 2 110 ? -25.028 -13.311 -69.554  1.00 74.73  ? 110 PHE B CG  1 
ATOM   3419  C CD1 . PHE B 2 110 ? -23.762 -13.819 -69.785  1.00 70.12  ? 110 PHE B CD1 1 
ATOM   3420  C CD2 . PHE B 2 110 ? -26.004 -14.161 -69.057  1.00 80.24  ? 110 PHE B CD2 1 
ATOM   3421  C CE1 . PHE B 2 110 ? -23.478 -15.151 -69.547  1.00 76.71  ? 110 PHE B CE1 1 
ATOM   3422  C CE2 . PHE B 2 110 ? -25.726 -15.494 -68.815  1.00 76.74  ? 110 PHE B CE2 1 
ATOM   3423  C CZ  . PHE B 2 110 ? -24.461 -15.989 -69.060  1.00 75.52  ? 110 PHE B CZ  1 
ATOM   3424  N N   . HIS B 2 111 ? -27.125 -11.959 -72.427  1.00 86.56  ? 111 HIS B N   1 
ATOM   3425  C CA  . HIS B 2 111 ? -27.930 -12.711 -73.384  1.00 88.49  ? 111 HIS B CA  1 
ATOM   3426  C C   . HIS B 2 111 ? -27.506 -12.422 -74.819  1.00 90.16  ? 111 HIS B C   1 
ATOM   3427  O O   . HIS B 2 111 ? -27.534 -13.320 -75.670  1.00 91.02  ? 111 HIS B O   1 
ATOM   3428  C CB  . HIS B 2 111 ? -29.410 -12.393 -73.183  1.00 88.96  ? 111 HIS B CB  1 
ATOM   3429  C CG  . HIS B 2 111 ? -29.943 -12.818 -71.850  1.00 87.29  ? 111 HIS B CG  1 
ATOM   3430  N ND1 . HIS B 2 111 ? -29.624 -14.028 -71.273  1.00 85.30  ? 111 HIS B ND1 1 
ATOM   3431  C CD2 . HIS B 2 111 ? -30.767 -12.191 -70.978  1.00 80.26  ? 111 HIS B CD2 1 
ATOM   3432  C CE1 . HIS B 2 111 ? -30.232 -14.130 -70.105  1.00 77.02  ? 111 HIS B CE1 1 
ATOM   3433  N NE2 . HIS B 2 111 ? -30.932 -13.029 -69.902  1.00 85.30  ? 111 HIS B NE2 1 
ATOM   3434  N N   . ASP B 2 112 ? -27.119 -11.176 -75.112  1.00 86.56  ? 112 ASP B N   1 
ATOM   3435  C CA  . ASP B 2 112 ? -26.654 -10.841 -76.455  1.00 92.27  ? 112 ASP B CA  1 
ATOM   3436  C C   . ASP B 2 112 ? -25.444 -11.681 -76.839  1.00 102.63 ? 112 ASP B C   1 
ATOM   3437  O O   . ASP B 2 112 ? -25.376 -12.227 -77.946  1.00 103.05 ? 112 ASP B O   1 
ATOM   3438  C CB  . ASP B 2 112 ? -26.311 -9.352  -76.547  1.00 100.44 ? 112 ASP B CB  1 
ATOM   3439  C CG  . ASP B 2 112 ? -27.539 -8.466  -76.561  1.00 106.37 ? 112 ASP B CG  1 
ATOM   3440  O OD1 . ASP B 2 112 ? -28.568 -8.863  -75.980  1.00 107.11 ? 112 ASP B OD1 1 
ATOM   3441  O OD2 . ASP B 2 112 ? -27.474 -7.373  -77.163  1.00 114.55 ? 112 ASP B OD2 1 
ATOM   3442  N N   . SER B 2 113 ? -24.473 -11.796 -75.930  1.00 90.95  ? 113 SER B N   1 
ATOM   3443  C CA  . SER B 2 113 ? -23.270 -12.563 -76.230  1.00 94.45  ? 113 SER B CA  1 
ATOM   3444  C C   . SER B 2 113 ? -23.591 -14.039 -76.430  1.00 93.25  ? 113 SER B C   1 
ATOM   3445  O O   . SER B 2 113 ? -23.076 -14.671 -77.359  1.00 100.96 ? 113 SER B O   1 
ATOM   3446  C CB  . SER B 2 113 ? -22.241 -12.385 -75.115  1.00 108.31 ? 113 SER B CB  1 
ATOM   3447  O OG  . SER B 2 113 ? -22.287 -13.470 -74.204  1.00 105.73 ? 113 SER B OG  1 
ATOM   3448  N N   . ASN B 2 114 ? -24.445 -14.604 -75.571  1.00 92.06  ? 114 ASN B N   1 
ATOM   3449  C CA  . ASN B 2 114 ? -24.797 -16.016 -75.698  1.00 93.12  ? 114 ASN B CA  1 
ATOM   3450  C C   . ASN B 2 114 ? -25.505 -16.290 -77.018  1.00 95.91  ? 114 ASN B C   1 
ATOM   3451  O O   . ASN B 2 114 ? -25.241 -17.304 -77.675  1.00 83.83  ? 114 ASN B O   1 
ATOM   3452  C CB  . ASN B 2 114 ? -25.676 -16.451 -74.527  1.00 90.79  ? 114 ASN B CB  1 
ATOM   3453  C CG  . ASN B 2 114 ? -25.010 -16.236 -73.185  1.00 92.25  ? 114 ASN B CG  1 
ATOM   3454  O OD1 . ASN B 2 114 ? -23.788 -16.123 -73.096  1.00 102.84 ? 114 ASN B OD1 1 
ATOM   3455  N ND2 . ASN B 2 114 ? -25.814 -16.184 -72.130  1.00 81.05  ? 114 ASN B ND2 1 
ATOM   3456  N N   . VAL B 2 115 ? -26.415 -15.401 -77.415  1.00 88.96  ? 115 VAL B N   1 
ATOM   3457  C CA  . VAL B 2 115 ? -27.092 -15.548 -78.699  1.00 94.97  ? 115 VAL B CA  1 
ATOM   3458  C C   . VAL B 2 115 ? -26.091 -15.424 -79.843  1.00 101.36 ? 115 VAL B C   1 
ATOM   3459  O O   . VAL B 2 115 ? -26.100 -16.221 -80.790  1.00 97.20  ? 115 VAL B O   1 
ATOM   3460  C CB  . VAL B 2 115 ? -28.231 -14.521 -78.822  1.00 93.79  ? 115 VAL B CB  1 
ATOM   3461  C CG1 . VAL B 2 115 ? -28.494 -14.207 -80.261  1.00 92.41  ? 115 VAL B CG1 1 
ATOM   3462  C CG2 . VAL B 2 115 ? -29.495 -15.057 -78.181  1.00 99.17  ? 115 VAL B CG2 1 
ATOM   3463  N N   . LYS B 2 116 ? -25.202 -14.428 -79.768  1.00 91.07  ? 116 LYS B N   1 
ATOM   3464  C CA  . LYS B 2 116 ? -24.197 -14.265 -80.814  1.00 97.78  ? 116 LYS B CA  1 
ATOM   3465  C C   . LYS B 2 116 ? -23.173 -15.393 -80.787  1.00 102.32 ? 116 LYS B C   1 
ATOM   3466  O O   . LYS B 2 116 ? -22.577 -15.710 -81.822  1.00 109.73 ? 116 LYS B O   1 
ATOM   3467  C CB  . LYS B 2 116 ? -23.498 -12.912 -80.677  1.00 102.29 ? 116 LYS B CB  1 
ATOM   3468  C CG  . LYS B 2 116 ? -22.807 -12.446 -81.953  1.00 109.23 ? 116 LYS B CG  1 
ATOM   3469  C CD  . LYS B 2 116 ? -21.924 -11.233 -81.704  1.00 114.60 ? 116 LYS B CD  1 
ATOM   3470  C CE  . LYS B 2 116 ? -21.523 -10.557 -83.009  1.00 110.64 ? 116 LYS B CE  1 
ATOM   3471  N NZ  . LYS B 2 116 ? -20.814 -11.483 -83.934  1.00 100.72 ? 116 LYS B NZ  1 
ATOM   3472  N N   . ASN B 2 117 ? -22.949 -16.002 -79.620  1.00 99.74  ? 117 ASN B N   1 
ATOM   3473  C CA  . ASN B 2 117 ? -22.046 -17.146 -79.549  1.00 97.60  ? 117 ASN B CA  1 
ATOM   3474  C C   . ASN B 2 117 ? -22.662 -18.372 -80.211  1.00 97.12  ? 117 ASN B C   1 
ATOM   3475  O O   . ASN B 2 117 ? -21.952 -19.176 -80.828  1.00 106.59 ? 117 ASN B O   1 
ATOM   3476  C CB  . ASN B 2 117 ? -21.681 -17.446 -78.094  1.00 111.76 ? 117 ASN B CB  1 
ATOM   3477  C CG  . ASN B 2 117 ? -20.648 -16.484 -77.541  1.00 115.83 ? 117 ASN B CG  1 
ATOM   3478  O OD1 . ASN B 2 117 ? -20.286 -15.503 -78.191  1.00 111.79 ? 117 ASN B OD1 1 
ATOM   3479  N ND2 . ASN B 2 117 ? -20.172 -16.758 -76.332  1.00 120.04 ? 117 ASN B ND2 1 
ATOM   3480  N N   . LEU B 2 118 ? -23.981 -18.539 -80.088  1.00 99.71  ? 118 LEU B N   1 
ATOM   3481  C CA  . LEU B 2 118 ? -24.637 -19.689 -80.702  1.00 97.89  ? 118 LEU B CA  1 
ATOM   3482  C C   . LEU B 2 118 ? -24.673 -19.554 -82.221  1.00 102.36 ? 118 LEU B C   1 
ATOM   3483  O O   . LEU B 2 118 ? -24.575 -20.554 -82.943  1.00 91.68  ? 118 LEU B O   1 
ATOM   3484  C CB  . LEU B 2 118 ? -26.048 -19.852 -80.137  1.00 87.32  ? 118 LEU B CB  1 
ATOM   3485  C CG  . LEU B 2 118 ? -26.451 -21.294 -79.822  1.00 89.61  ? 118 LEU B CG  1 
ATOM   3486  C CD1 . LEU B 2 118 ? -25.474 -21.903 -78.831  1.00 90.00  ? 118 LEU B CD1 1 
ATOM   3487  C CD2 . LEU B 2 118 ? -27.873 -21.358 -79.288  1.00 93.47  ? 118 LEU B CD2 1 
ATOM   3488  N N   . TYR B 2 119 ? -24.831 -18.327 -82.723  1.00 99.26  ? 119 TYR B N   1 
ATOM   3489  C CA  . TYR B 2 119 ? -24.793 -18.106 -84.165  1.00 93.95  ? 119 TYR B CA  1 
ATOM   3490  C C   . TYR B 2 119 ? -23.415 -18.421 -84.736  1.00 106.77 ? 119 TYR B C   1 
ATOM   3491  O O   . TYR B 2 119 ? -23.301 -19.034 -85.805  1.00 108.20 ? 119 TYR B O   1 
ATOM   3492  C CB  . TYR B 2 119 ? -25.192 -16.664 -84.483  1.00 100.43 ? 119 TYR B CB  1 
ATOM   3493  C CG  . TYR B 2 119 ? -25.091 -16.289 -85.946  1.00 106.92 ? 119 TYR B CG  1 
ATOM   3494  C CD1 . TYR B 2 119 ? -26.135 -16.548 -86.825  1.00 102.30 ? 119 TYR B CD1 1 
ATOM   3495  C CD2 . TYR B 2 119 ? -23.957 -15.661 -86.446  1.00 106.47 ? 119 TYR B CD2 1 
ATOM   3496  C CE1 . TYR B 2 119 ? -26.050 -16.195 -88.160  1.00 108.25 ? 119 TYR B CE1 1 
ATOM   3497  C CE2 . TYR B 2 119 ? -23.860 -15.310 -87.779  1.00 99.54  ? 119 TYR B CE2 1 
ATOM   3498  C CZ  . TYR B 2 119 ? -24.908 -15.580 -88.632  1.00 105.29 ? 119 TYR B CZ  1 
ATOM   3499  O OH  . TYR B 2 119 ? -24.815 -15.230 -89.960  1.00 107.33 ? 119 TYR B OH  1 
ATOM   3500  N N   . ASP B 2 120 ? -22.355 -18.009 -84.036  1.00 103.38 ? 120 ASP B N   1 
ATOM   3501  C CA  . ASP B 2 120 ? -21.002 -18.262 -84.524  1.00 104.12 ? 120 ASP B CA  1 
ATOM   3502  C C   . ASP B 2 120 ? -20.677 -19.750 -84.524  1.00 106.05 ? 120 ASP B C   1 
ATOM   3503  O O   . ASP B 2 120 ? -19.958 -20.231 -85.407  1.00 109.34 ? 120 ASP B O   1 
ATOM   3504  C CB  . ASP B 2 120 ? -19.983 -17.489 -83.687  1.00 102.03 ? 120 ASP B CB  1 
ATOM   3505  C CG  . ASP B 2 120 ? -19.878 -16.033 -84.095  1.00 113.93 ? 120 ASP B CG  1 
ATOM   3506  O OD1 . ASP B 2 120 ? -20.687 -15.591 -84.938  1.00 119.48 ? 120 ASP B OD1 1 
ATOM   3507  O OD2 . ASP B 2 120 ? -18.981 -15.333 -83.581  1.00 117.10 ? 120 ASP B OD2 1 
ATOM   3508  N N   . LYS B 2 121 ? -21.190 -20.495 -83.540  1.00 107.09 ? 121 LYS B N   1 
ATOM   3509  C CA  . LYS B 2 121 ? -20.965 -21.937 -83.517  1.00 102.07 ? 121 LYS B CA  1 
ATOM   3510  C C   . LYS B 2 121 ? -21.550 -22.603 -84.755  1.00 107.44 ? 121 LYS B C   1 
ATOM   3511  O O   . LYS B 2 121 ? -20.917 -23.478 -85.357  1.00 112.17 ? 121 LYS B O   1 
ATOM   3512  C CB  . LYS B 2 121 ? -21.562 -22.544 -82.248  1.00 86.58  ? 121 LYS B CB  1 
ATOM   3513  C CG  . LYS B 2 121 ? -20.834 -22.164 -80.968  1.00 97.75  ? 121 LYS B CG  1 
ATOM   3514  C CD  . LYS B 2 121 ? -21.551 -22.685 -79.724  1.00 115.80 ? 121 LYS B CD  1 
ATOM   3515  C CE  . LYS B 2 121 ? -21.239 -24.153 -79.444  1.00 102.81 ? 121 LYS B CE  1 
ATOM   3516  N NZ  . LYS B 2 121 ? -21.926 -25.096 -80.371  1.00 92.84  ? 121 LYS B NZ  1 
ATOM   3517  N N   . VAL B 2 122 ? -22.760 -22.202 -85.151  1.00 108.02 ? 122 VAL B N   1 
ATOM   3518  C CA  . VAL B 2 122 ? -23.361 -22.742 -86.366  1.00 105.39 ? 122 VAL B CA  1 
ATOM   3519  C C   . VAL B 2 122 ? -22.617 -22.242 -87.599  1.00 100.36 ? 122 VAL B C   1 
ATOM   3520  O O   . VAL B 2 122 ? -22.419 -22.989 -88.565  1.00 106.55 ? 122 VAL B O   1 
ATOM   3521  C CB  . VAL B 2 122 ? -24.859 -22.390 -86.422  1.00 105.60 ? 122 VAL B CB  1 
ATOM   3522  C CG1 . VAL B 2 122 ? -25.507 -23.015 -87.647  1.00 98.85  ? 122 VAL B CG1 1 
ATOM   3523  C CG2 . VAL B 2 122 ? -25.557 -22.850 -85.152  1.00 95.97  ? 122 VAL B CG2 1 
ATOM   3524  N N   . ARG B 2 123 ? -22.192 -20.975 -87.587  1.00 101.45 ? 123 ARG B N   1 
ATOM   3525  C CA  . ARG B 2 123 ? -21.453 -20.425 -88.721  1.00 96.76  ? 123 ARG B CA  1 
ATOM   3526  C C   . ARG B 2 123 ? -20.152 -21.183 -88.950  1.00 104.98 ? 123 ARG B C   1 
ATOM   3527  O O   . ARG B 2 123 ? -19.767 -21.443 -90.096  1.00 108.24 ? 123 ARG B O   1 
ATOM   3528  C CB  . ARG B 2 123 ? -21.164 -18.940 -88.493  1.00 105.36 ? 123 ARG B CB  1 
ATOM   3529  C CG  . ARG B 2 123 ? -20.528 -18.246 -89.689  1.00 101.45 ? 123 ARG B CG  1 
ATOM   3530  C CD  . ARG B 2 123 ? -19.633 -17.084 -89.276  1.00 108.20 ? 123 ARG B CD  1 
ATOM   3531  N NE  . ARG B 2 123 ? -18.328 -17.532 -88.801  1.00 108.73 ? 123 ARG B NE  1 
ATOM   3532  C CZ  . ARG B 2 123 ? -17.239 -16.775 -88.777  1.00 108.89 ? 123 ARG B CZ  1 
ATOM   3533  N NH1 . ARG B 2 123 ? -17.259 -15.523 -89.205  1.00 106.10 ? 123 ARG B NH1 1 
ATOM   3534  N NH2 . ARG B 2 123 ? -16.100 -17.289 -88.323  1.00 108.44 ? 123 ARG B NH2 1 
ATOM   3535  N N   . LEU B 2 124 ? -19.458 -21.539 -87.867  1.00 105.70 ? 124 LEU B N   1 
ATOM   3536  C CA  . LEU B 2 124 ? -18.194 -22.260 -87.986  1.00 103.20 ? 124 LEU B CA  1 
ATOM   3537  C C   . LEU B 2 124 ? -18.391 -23.647 -88.586  1.00 108.87 ? 124 LEU B C   1 
ATOM   3538  O O   . LEU B 2 124 ? -17.560 -24.107 -89.375  1.00 113.76 ? 124 LEU B O   1 
ATOM   3539  C CB  . LEU B 2 124 ? -17.520 -22.361 -86.618  1.00 107.38 ? 124 LEU B CB  1 
ATOM   3540  C CG  . LEU B 2 124 ? -16.505 -21.286 -86.221  1.00 106.56 ? 124 LEU B CG  1 
ATOM   3541  C CD1 . LEU B 2 124 ? -16.993 -19.891 -86.572  1.00 89.96  ? 124 LEU B CD1 1 
ATOM   3542  C CD2 . LEU B 2 124 ? -16.203 -21.382 -84.734  1.00 120.70 ? 124 LEU B CD2 1 
ATOM   3543  N N   . GLN B 2 125 ? -19.465 -24.342 -88.204  1.00 110.64 ? 125 GLN B N   1 
ATOM   3544  C CA  . GLN B 2 125 ? -19.673 -25.704 -88.688  1.00 107.41 ? 125 GLN B CA  1 
ATOM   3545  C C   . GLN B 2 125 ? -20.047 -25.725 -90.166  1.00 114.82 ? 125 GLN B C   1 
ATOM   3546  O O   . GLN B 2 125 ? -19.476 -26.492 -90.950  1.00 114.03 ? 125 GLN B O   1 
ATOM   3547  C CB  . GLN B 2 125 ? -20.754 -26.397 -87.859  1.00 103.60 ? 125 GLN B CB  1 
ATOM   3548  C CG  . GLN B 2 125 ? -20.446 -26.500 -86.378  1.00 91.99  ? 125 GLN B CG  1 
ATOM   3549  C CD  . GLN B 2 125 ? -21.586 -27.121 -85.596  1.00 106.46 ? 125 GLN B CD  1 
ATOM   3550  O OE1 . GLN B 2 125 ? -21.917 -28.292 -85.781  1.00 97.68  ? 125 GLN B OE1 1 
ATOM   3551  N NE2 . GLN B 2 125 ? -22.201 -26.333 -84.720  1.00 110.94 ? 125 GLN B NE2 1 
ATOM   3552  N N   . LEU B 2 126 ? -21.008 -24.887 -90.566  1.00 109.54 ? 126 LEU B N   1 
ATOM   3553  C CA  . LEU B 2 126 ? -21.553 -24.976 -91.918  1.00 111.59 ? 126 LEU B CA  1 
ATOM   3554  C C   . LEU B 2 126 ? -20.548 -24.507 -92.964  1.00 122.27 ? 126 LEU B C   1 
ATOM   3555  O O   . LEU B 2 126 ? -20.406 -25.138 -94.020  1.00 128.64 ? 126 LEU B O   1 
ATOM   3556  C CB  . LEU B 2 126 ? -22.850 -24.171 -92.014  1.00 104.95 ? 126 LEU B CB  1 
ATOM   3557  C CG  . LEU B 2 126 ? -23.949 -24.549 -91.016  1.00 100.22 ? 126 LEU B CG  1 
ATOM   3558  C CD1 . LEU B 2 126 ? -25.248 -23.829 -91.345  1.00 100.64 ? 126 LEU B CD1 1 
ATOM   3559  C CD2 . LEU B 2 126 ? -24.156 -26.057 -90.974  1.00 104.04 ? 126 LEU B CD2 1 
ATOM   3560  N N   . ARG B 2 127 ? -19.850 -23.407 -92.692  1.00 117.56 ? 127 ARG B N   1 
ATOM   3561  C CA  . ARG B 2 127 ? -18.845 -22.826 -93.596  1.00 121.28 ? 127 ARG B CA  1 
ATOM   3562  C C   . ARG B 2 127 ? -19.524 -22.518 -94.929  1.00 123.10 ? 127 ARG B C   1 
ATOM   3563  O O   . ARG B 2 127 ? -20.629 -21.952 -94.930  1.00 107.92 ? 127 ARG B O   1 
ATOM   3564  C CB  . ARG B 2 127 ? -17.649 -23.755 -93.683  1.00 116.06 ? 127 ARG B CB  1 
ATOM   3565  C CG  . ARG B 2 127 ? -17.117 -24.198 -92.360  1.00 117.41 ? 127 ARG B CG  1 
ATOM   3566  C CD  . ARG B 2 127 ? -15.638 -24.578 -92.450  1.00 126.04 ? 127 ARG B CD  1 
ATOM   3567  N NE  . ARG B 2 127 ? -15.267 -25.933 -92.926  1.00 139.42 ? 127 ARG B NE  1 
ATOM   3568  C CZ  . ARG B 2 127 ? -14.916 -26.973 -92.149  1.00 146.68 ? 127 ARG B CZ  1 
ATOM   3569  N NH1 . ARG B 2 127 ? -14.976 -26.917 -90.815  1.00 148.84 ? 127 ARG B NH1 1 
ATOM   3570  N NH2 . ARG B 2 127 ? -14.335 -28.039 -92.731  1.00 144.64 ? 127 ARG B NH2 1 
ATOM   3571  N N   . ASP B 2 128 ? -18.918 -22.863 -96.066  1.00 129.63 ? 128 ASP B N   1 
ATOM   3572  C CA  . ASP B 2 128 ? -19.464 -22.542 -97.377  1.00 127.69 ? 128 ASP B CA  1 
ATOM   3573  C C   . ASP B 2 128 ? -20.675 -23.388 -97.748  1.00 121.32 ? 128 ASP B C   1 
ATOM   3574  O O   . ASP B 2 128 ? -21.316 -23.100 -98.765  1.00 106.54 ? 128 ASP B O   1 
ATOM   3575  C CB  . ASP B 2 128 ? -18.376 -22.705 -98.437  1.00 122.63 ? 128 ASP B CB  1 
ATOM   3576  C CG  . ASP B 2 128 ? -17.489 -23.907 -98.176  1.00 126.50 ? 128 ASP B CG  1 
ATOM   3577  O OD1 . ASP B 2 128 ? -18.031 -25.002 -97.911  1.00 129.53 ? 128 ASP B OD1 1 
ATOM   3578  O OD2 . ASP B 2 128 ? -16.251 -23.758 -98.235  1.00 131.10 ? 128 ASP B OD2 1 
ATOM   3579  N N   . ASN B 2 129 ? -21.002 -24.421 -96.968  1.00 119.53 ? 129 ASN B N   1 
ATOM   3580  C CA  . ASN B 2 129 ? -22.140 -25.273 -97.298  1.00 122.90 ? 129 ASN B CA  1 
ATOM   3581  C C   . ASN B 2 129 ? -23.479 -24.572 -97.133  1.00 126.59 ? 129 ASN B C   1 
ATOM   3582  O O   . ASN B 2 129 ? -24.499 -25.124 -97.558  1.00 121.15 ? 129 ASN B O   1 
ATOM   3583  C CB  . ASN B 2 129 ? -22.144 -26.533 -96.437  1.00 121.87 ? 129 ASN B CB  1 
ATOM   3584  C CG  . ASN B 2 129 ? -20.907 -27.376 -96.631  1.00 131.94 ? 129 ASN B CG  1 
ATOM   3585  O OD1 . ASN B 2 129 ? -20.480 -27.627 -97.759  1.00 128.54 ? 129 ASN B OD1 1 
ATOM   3586  N ND2 . ASN B 2 129 ? -20.320 -27.820 -95.525  1.00 130.98 ? 129 ASN B ND2 1 
ATOM   3587  N N   . ALA B 2 130 ? -23.508 -23.399 -96.509  1.00 121.60 ? 130 ALA B N   1 
ATOM   3588  C CA  . ALA B 2 130 ? -24.736 -22.639 -96.350  1.00 115.63 ? 130 ALA B CA  1 
ATOM   3589  C C   . ALA B 2 130 ? -24.416 -21.158 -96.479  1.00 114.53 ? 130 ALA B C   1 
ATOM   3590  O O   . ALA B 2 130 ? -23.267 -20.733 -96.331  1.00 105.74 ? 130 ALA B O   1 
ATOM   3591  C CB  . ALA B 2 130 ? -25.416 -22.931 -95.006  1.00 108.55 ? 130 ALA B CB  1 
ATOM   3592  N N   . LYS B 2 131 ? -25.450 -20.373 -96.764  1.00 114.46 ? 131 LYS B N   1 
ATOM   3593  C CA  . LYS B 2 131 ? -25.319 -18.940 -96.979  1.00 123.70 ? 131 LYS B CA  1 
ATOM   3594  C C   . LYS B 2 131 ? -25.978 -18.191 -95.829  1.00 120.62 ? 131 LYS B C   1 
ATOM   3595  O O   . LYS B 2 131 ? -27.119 -18.491 -95.461  1.00 108.73 ? 131 LYS B O   1 
ATOM   3596  C CB  . LYS B 2 131 ? -25.951 -18.527 -98.310  1.00 121.31 ? 131 LYS B CB  1 
ATOM   3597  C CG  . LYS B 2 131 ? -25.461 -17.192 -98.850  1.00 116.03 ? 131 LYS B CG  1 
ATOM   3598  C CD  . LYS B 2 131 ? -26.248 -16.776 -100.084 1.00 114.35 ? 131 LYS B CD  1 
ATOM   3599  C CE  . LYS B 2 131 ? -25.530 -15.684 -100.859 1.00 118.06 ? 131 LYS B CE  1 
ATOM   3600  N NZ  . LYS B 2 131 ? -24.240 -16.167 -101.426 1.00 131.27 ? 131 LYS B NZ  1 
ATOM   3601  N N   . GLU B 2 132 ? -25.260 -17.221 -95.266  1.00 116.60 ? 132 GLU B N   1 
ATOM   3602  C CA  . GLU B 2 132 ? -25.791 -16.399 -94.185  1.00 112.26 ? 132 GLU B CA  1 
ATOM   3603  C C   . GLU B 2 132 ? -26.744 -15.371 -94.782  1.00 103.02 ? 132 GLU B C   1 
ATOM   3604  O O   . GLU B 2 132 ? -26.318 -14.472 -95.514  1.00 103.43 ? 132 GLU B O   1 
ATOM   3605  C CB  . GLU B 2 132 ? -24.660 -15.715 -93.423  1.00 116.30 ? 132 GLU B CB  1 
ATOM   3606  C CG  . GLU B 2 132 ? -23.347 -16.479 -93.426  1.00 119.48 ? 132 GLU B CG  1 
ATOM   3607  C CD  . GLU B 2 132 ? -22.232 -15.714 -92.738  1.00 126.21 ? 132 GLU B CD  1 
ATOM   3608  O OE1 . GLU B 2 132 ? -22.515 -15.022 -91.737  1.00 123.87 ? 132 GLU B OE1 1 
ATOM   3609  O OE2 . GLU B 2 132 ? -21.075 -15.798 -93.203  1.00 126.40 ? 132 GLU B OE2 1 
ATOM   3610  N N   . LEU B 2 133 ? -28.037 -15.506 -94.478  1.00 102.07 ? 133 LEU B N   1 
ATOM   3611  C CA  . LEU B 2 133 ? -29.020 -14.566 -95.007  1.00 107.14 ? 133 LEU B CA  1 
ATOM   3612  C C   . LEU B 2 133 ? -28.772 -13.155 -94.491  1.00 113.69 ? 133 LEU B C   1 
ATOM   3613  O O   . LEU B 2 133 ? -28.845 -12.185 -95.253  1.00 120.09 ? 133 LEU B O   1 
ATOM   3614  C CB  . LEU B 2 133 ? -30.433 -15.026 -94.648  1.00 108.02 ? 133 LEU B CB  1 
ATOM   3615  C CG  . LEU B 2 133 ? -30.829 -16.425 -95.119  1.00 113.00 ? 133 LEU B CG  1 
ATOM   3616  C CD1 . LEU B 2 133 ? -32.294 -16.700 -94.813  1.00 115.78 ? 133 LEU B CD1 1 
ATOM   3617  C CD2 . LEU B 2 133 ? -30.545 -16.588 -96.603  1.00 112.39 ? 133 LEU B CD2 1 
ATOM   3618  N N   . GLY B 2 134 ? -28.475 -13.021 -93.201  1.00 119.71 ? 134 GLY B N   1 
ATOM   3619  C CA  . GLY B 2 134 ? -28.251 -11.718 -92.613  1.00 112.38 ? 134 GLY B CA  1 
ATOM   3620  C C   . GLY B 2 134 ? -29.076 -11.486 -91.364  1.00 109.66 ? 134 GLY B C   1 
ATOM   3621  O O   . GLY B 2 134 ? -28.661 -10.739 -90.472  1.00 111.83 ? 134 GLY B O   1 
ATOM   3622  N N   . ASN B 2 135 ? -30.246 -12.117 -91.284  1.00 106.21 ? 135 ASN B N   1 
ATOM   3623  C CA  . ASN B 2 135 ? -31.113 -11.963 -90.125  1.00 117.78 ? 135 ASN B CA  1 
ATOM   3624  C C   . ASN B 2 135 ? -30.813 -12.975 -89.027  1.00 116.39 ? 135 ASN B C   1 
ATOM   3625  O O   . ASN B 2 135 ? -31.445 -12.927 -87.966  1.00 117.16 ? 135 ASN B O   1 
ATOM   3626  C CB  . ASN B 2 135 ? -32.594 -12.041 -90.546  1.00 121.80 ? 135 ASN B CB  1 
ATOM   3627  C CG  . ASN B 2 135 ? -33.184 -13.446 -90.436  1.00 127.85 ? 135 ASN B CG  1 
ATOM   3628  O OD1 . ASN B 2 135 ? -33.507 -13.916 -89.344  1.00 122.85 ? 135 ASN B OD1 1 
ATOM   3629  N ND2 . ASN B 2 135 ? -33.368 -14.100 -91.579  1.00 119.05 ? 135 ASN B ND2 1 
ATOM   3630  N N   . GLY B 2 136 ? -29.844 -13.862 -89.236  1.00 110.39 ? 136 GLY B N   1 
ATOM   3631  C CA  . GLY B 2 136 ? -29.534 -14.905 -88.280  1.00 112.26 ? 136 GLY B CA  1 
ATOM   3632  C C   . GLY B 2 136 ? -29.870 -16.300 -88.752  1.00 111.68 ? 136 GLY B C   1 
ATOM   3633  O O   . GLY B 2 136 ? -29.731 -17.250 -87.972  1.00 104.20 ? 136 GLY B O   1 
ATOM   3634  N N   . CYS B 2 137 ? -30.310 -16.455 -89.996  1.00 115.71 ? 137 CYS B N   1 
ATOM   3635  C CA  . CYS B 2 137 ? -30.618 -17.750 -90.576  1.00 105.34 ? 137 CYS B CA  1 
ATOM   3636  C C   . CYS B 2 137 ? -29.542 -18.144 -91.579  1.00 103.58 ? 137 CYS B C   1 
ATOM   3637  O O   . CYS B 2 137 ? -28.800 -17.304 -92.095  1.00 105.17 ? 137 CYS B O   1 
ATOM   3638  C CB  . CYS B 2 137 ? -31.988 -17.738 -91.264  1.00 105.85 ? 137 CYS B CB  1 
ATOM   3639  S SG  . CYS B 2 137 ? -33.393 -17.368 -90.189  1.00 131.58 ? 137 CYS B SG  1 
ATOM   3640  N N   . PHE B 2 138 ? -29.464 -19.445 -91.845  1.00 107.91 ? 138 PHE B N   1 
ATOM   3641  C CA  . PHE B 2 138 ? -28.563 -19.999 -92.845  1.00 114.38 ? 138 PHE B CA  1 
ATOM   3642  C C   . PHE B 2 138 ? -29.384 -20.731 -93.895  1.00 115.58 ? 138 PHE B C   1 
ATOM   3643  O O   . PHE B 2 138 ? -30.196 -21.597 -93.556  1.00 103.81 ? 138 PHE B O   1 
ATOM   3644  C CB  . PHE B 2 138 ? -27.549 -20.959 -92.215  1.00 108.54 ? 138 PHE B CB  1 
ATOM   3645  C CG  . PHE B 2 138 ? -26.713 -20.343 -91.131  1.00 98.58  ? 138 PHE B CG  1 
ATOM   3646  C CD1 . PHE B 2 138 ? -27.140 -20.360 -89.814  1.00 100.80 ? 138 PHE B CD1 1 
ATOM   3647  C CD2 . PHE B 2 138 ? -25.492 -19.761 -91.426  1.00 105.47 ? 138 PHE B CD2 1 
ATOM   3648  C CE1 . PHE B 2 138 ? -26.370 -19.798 -88.814  1.00 97.94  ? 138 PHE B CE1 1 
ATOM   3649  C CE2 . PHE B 2 138 ? -24.716 -19.199 -90.430  1.00 103.69 ? 138 PHE B CE2 1 
ATOM   3650  C CZ  . PHE B 2 138 ? -25.155 -19.221 -89.123  1.00 96.94  ? 138 PHE B CZ  1 
ATOM   3651  N N   . GLU B 2 139 ? -29.173 -20.387 -95.163  1.00 123.13 ? 139 GLU B N   1 
ATOM   3652  C CA  . GLU B 2 139 ? -29.821 -21.077 -96.274  1.00 119.55 ? 139 GLU B CA  1 
ATOM   3653  C C   . GLU B 2 139 ? -28.900 -22.201 -96.736  1.00 117.72 ? 139 GLU B C   1 
ATOM   3654  O O   . GLU B 2 139 ? -27.844 -21.946 -97.323  1.00 109.26 ? 139 GLU B O   1 
ATOM   3655  C CB  . GLU B 2 139 ? -30.127 -20.108 -97.414  1.00 120.01 ? 139 GLU B CB  1 
ATOM   3656  C CG  . GLU B 2 139 ? -30.659 -20.764 -98.687  1.00 128.02 ? 139 GLU B CG  1 
ATOM   3657  C CD  . GLU B 2 139 ? -32.161 -20.995 -98.660  1.00 123.17 ? 139 GLU B CD  1 
ATOM   3658  O OE1 . GLU B 2 139 ? -32.780 -20.801 -97.595  1.00 121.22 ? 139 GLU B OE1 1 
ATOM   3659  O OE2 . GLU B 2 139 ? -32.724 -21.367 -99.712  1.00 125.76 ? 139 GLU B OE2 1 
ATOM   3660  N N   . PHE B 2 140 ? -29.294 -23.442 -96.460  1.00 118.01 ? 140 PHE B N   1 
ATOM   3661  C CA  . PHE B 2 140 ? -28.473 -24.585 -96.834  1.00 118.08 ? 140 PHE B CA  1 
ATOM   3662  C C   . PHE B 2 140 ? -28.430 -24.751 -98.347  1.00 119.07 ? 140 PHE B C   1 
ATOM   3663  O O   . PHE B 2 140 ? -29.449 -24.632 -99.034  1.00 102.58 ? 140 PHE B O   1 
ATOM   3664  C CB  . PHE B 2 140 ? -29.006 -25.863 -96.187  1.00 101.38 ? 140 PHE B CB  1 
ATOM   3665  C CG  . PHE B 2 140 ? -28.593 -26.038 -94.755  1.00 112.11 ? 140 PHE B CG  1 
ATOM   3666  C CD1 . PHE B 2 140 ? -27.295 -26.401 -94.437  1.00 113.71 ? 140 PHE B CD1 1 
ATOM   3667  C CD2 . PHE B 2 140 ? -29.504 -25.854 -93.728  1.00 114.81 ? 140 PHE B CD2 1 
ATOM   3668  C CE1 . PHE B 2 140 ? -26.910 -26.568 -93.120  1.00 110.84 ? 140 PHE B CE1 1 
ATOM   3669  C CE2 . PHE B 2 140 ? -29.125 -26.020 -92.408  1.00 100.83 ? 140 PHE B CE2 1 
ATOM   3670  C CZ  . PHE B 2 140 ? -27.826 -26.378 -92.104  1.00 105.29 ? 140 PHE B CZ  1 
ATOM   3671  N N   . TYR B 2 141 ? -27.236 -25.031 -98.863  1.00 123.24 ? 141 TYR B N   1 
ATOM   3672  C CA  . TYR B 2 141 ? -27.043 -25.337 -100.272 1.00 115.86 ? 141 TYR B CA  1 
ATOM   3673  C C   . TYR B 2 141 ? -27.284 -26.806 -100.595 1.00 115.71 ? 141 TYR B C   1 
ATOM   3674  O O   . TYR B 2 141 ? -27.209 -27.188 -101.766 1.00 121.29 ? 141 TYR B O   1 
ATOM   3675  C CB  . TYR B 2 141 ? -25.628 -24.946 -100.710 1.00 117.85 ? 141 TYR B CB  1 
ATOM   3676  C CG  . TYR B 2 141 ? -25.411 -23.458 -100.854 1.00 119.17 ? 141 TYR B CG  1 
ATOM   3677  C CD1 . TYR B 2 141 ? -26.477 -22.599 -101.090 1.00 110.31 ? 141 TYR B CD1 1 
ATOM   3678  C CD2 . TYR B 2 141 ? -24.137 -22.912 -100.760 1.00 123.67 ? 141 TYR B CD2 1 
ATOM   3679  C CE1 . TYR B 2 141 ? -26.280 -21.238 -101.226 1.00 108.32 ? 141 TYR B CE1 1 
ATOM   3680  C CE2 . TYR B 2 141 ? -23.930 -21.554 -100.894 1.00 122.03 ? 141 TYR B CE2 1 
ATOM   3681  C CZ  . TYR B 2 141 ? -25.004 -20.721 -101.127 1.00 116.01 ? 141 TYR B CZ  1 
ATOM   3682  O OH  . TYR B 2 141 ? -24.800 -19.368 -101.261 1.00 94.83  ? 141 TYR B OH  1 
ATOM   3683  N N   . HIS B 2 142 ? -27.565 -27.634 -99.592  1.00 108.22 ? 142 HIS B N   1 
ATOM   3684  C CA  . HIS B 2 142 ? -27.788 -29.059 -99.782  1.00 107.43 ? 142 HIS B CA  1 
ATOM   3685  C C   . HIS B 2 142 ? -29.069 -29.465 -99.062  1.00 111.61 ? 142 HIS B C   1 
ATOM   3686  O O   . HIS B 2 142 ? -29.775 -28.634 -98.483  1.00 109.25 ? 142 HIS B O   1 
ATOM   3687  C CB  . HIS B 2 142 ? -26.589 -29.876 -99.280  1.00 111.33 ? 142 HIS B CB  1 
ATOM   3688  C CG  . HIS B 2 142 ? -26.347 -29.755 -97.808  1.00 112.57 ? 142 HIS B CG  1 
ATOM   3689  N ND1 . HIS B 2 142 ? -27.003 -30.535 -96.879  1.00 108.28 ? 142 HIS B ND1 1 
ATOM   3690  C CD2 . HIS B 2 142 ? -25.523 -28.945 -97.103  1.00 111.72 ? 142 HIS B CD2 1 
ATOM   3691  C CE1 . HIS B 2 142 ? -26.591 -30.212 -95.666  1.00 108.44 ? 142 HIS B CE1 1 
ATOM   3692  N NE2 . HIS B 2 142 ? -25.693 -29.249 -95.774  1.00 109.06 ? 142 HIS B NE2 1 
ATOM   3693  N N   . LYS B 2 143 ? -29.369 -30.761 -99.105  1.00 109.71 ? 143 LYS B N   1 
ATOM   3694  C CA  . LYS B 2 143 ? -30.544 -31.308 -98.438  1.00 112.90 ? 143 LYS B CA  1 
ATOM   3695  C C   . LYS B 2 143 ? -30.164 -31.734 -97.026  1.00 114.92 ? 143 LYS B C   1 
ATOM   3696  O O   . LYS B 2 143 ? -29.277 -32.575 -96.840  1.00 114.98 ? 143 LYS B O   1 
ATOM   3697  C CB  . LYS B 2 143 ? -31.119 -32.483 -99.226  1.00 100.75 ? 143 LYS B CB  1 
ATOM   3698  C CG  . LYS B 2 143 ? -31.870 -32.060 -100.474 1.00 107.30 ? 143 LYS B CG  1 
ATOM   3699  C CD  . LYS B 2 143 ? -33.080 -31.211 -100.115 1.00 112.04 ? 143 LYS B CD  1 
ATOM   3700  C CE  . LYS B 2 143 ? -33.534 -30.365 -101.293 1.00 120.11 ? 143 LYS B CE  1 
ATOM   3701  N NZ  . LYS B 2 143 ? -33.771 -31.184 -102.513 1.00 122.99 ? 143 LYS B NZ  1 
ATOM   3702  N N   . CYS B 2 144 ? -30.834 -31.151 -96.037  1.00 106.55 ? 144 CYS B N   1 
ATOM   3703  C CA  . CYS B 2 144 ? -30.534 -31.376 -94.628  1.00 110.12 ? 144 CYS B CA  1 
ATOM   3704  C C   . CYS B 2 144 ? -31.741 -32.047 -93.988  1.00 103.62 ? 144 CYS B C   1 
ATOM   3705  O O   . CYS B 2 144 ? -32.770 -31.399 -93.762  1.00 95.15  ? 144 CYS B O   1 
ATOM   3706  C CB  . CYS B 2 144 ? -30.191 -30.055 -93.940  1.00 105.94 ? 144 CYS B CB  1 
ATOM   3707  S SG  . CYS B 2 144 ? -29.629 -30.163 -92.226  1.00 120.03 ? 144 CYS B SG  1 
ATOM   3708  N N   . ASP B 2 145 ? -31.621 -33.341 -93.699  1.00 100.84 ? 145 ASP B N   1 
ATOM   3709  C CA  . ASP B 2 145 ? -32.710 -34.056 -93.053  1.00 98.04  ? 145 ASP B CA  1 
ATOM   3710  C C   . ASP B 2 145 ? -32.820 -33.615 -91.595  1.00 103.38 ? 145 ASP B C   1 
ATOM   3711  O O   . ASP B 2 145 ? -32.084 -32.746 -91.118  1.00 98.73  ? 145 ASP B O   1 
ATOM   3712  C CB  . ASP B 2 145 ? -32.514 -35.569 -93.178  1.00 83.89  ? 145 ASP B CB  1 
ATOM   3713  C CG  . ASP B 2 145 ? -31.254 -36.075 -92.479  1.00 104.20 ? 145 ASP B CG  1 
ATOM   3714  O OD1 . ASP B 2 145 ? -30.519 -35.274 -91.869  1.00 111.05 ? 145 ASP B OD1 1 
ATOM   3715  O OD2 . ASP B 2 145 ? -30.998 -37.297 -92.544  1.00 108.93 ? 145 ASP B OD2 1 
ATOM   3716  N N   . ASN B 2 146 ? -33.754 -34.226 -90.869  1.00 99.73  ? 146 ASN B N   1 
ATOM   3717  C CA  . ASN B 2 146 ? -33.910 -33.880 -89.464  1.00 90.07  ? 146 ASN B CA  1 
ATOM   3718  C C   . ASN B 2 146 ? -32.703 -34.285 -88.628  1.00 92.87  ? 146 ASN B C   1 
ATOM   3719  O O   . ASN B 2 146 ? -32.516 -33.741 -87.535  1.00 102.21 ? 146 ASN B O   1 
ATOM   3720  C CB  . ASN B 2 146 ? -35.179 -34.514 -88.901  1.00 89.89  ? 146 ASN B CB  1 
ATOM   3721  C CG  . ASN B 2 146 ? -36.432 -33.809 -89.372  1.00 85.53  ? 146 ASN B CG  1 
ATOM   3722  O OD1 . ASN B 2 146 ? -36.385 -32.649 -89.783  1.00 78.11  ? 146 ASN B OD1 1 
ATOM   3723  N ND2 . ASN B 2 146 ? -37.562 -34.503 -89.312  1.00 71.59  ? 146 ASN B ND2 1 
ATOM   3724  N N   . GLU B 2 147 ? -31.881 -35.217 -89.108  1.00 93.95  ? 147 GLU B N   1 
ATOM   3725  C CA  . GLU B 2 147 ? -30.686 -35.595 -88.370  1.00 99.04  ? 147 GLU B CA  1 
ATOM   3726  C C   . GLU B 2 147 ? -29.428 -34.895 -88.861  1.00 96.45  ? 147 GLU B C   1 
ATOM   3727  O O   . GLU B 2 147 ? -28.408 -34.933 -88.164  1.00 105.72 ? 147 GLU B O   1 
ATOM   3728  C CB  . GLU B 2 147 ? -30.509 -37.117 -88.398  1.00 94.12  ? 147 GLU B CB  1 
ATOM   3729  C CG  . GLU B 2 147 ? -31.828 -37.930 -88.272  1.00 96.98  ? 147 GLU B CG  1 
ATOM   3730  C CD  . GLU B 2 147 ? -32.762 -37.541 -87.102  1.00 120.64 ? 147 GLU B CD  1 
ATOM   3731  O OE1 . GLU B 2 147 ? -32.552 -36.522 -86.403  1.00 116.49 ? 147 GLU B OE1 1 
ATOM   3732  O OE2 . GLU B 2 147 ? -33.742 -38.287 -86.886  1.00 120.97 ? 147 GLU B OE2 1 
ATOM   3733  N N   . CYS B 2 148 ? -29.475 -34.264 -90.034  1.00 95.61  ? 148 CYS B N   1 
ATOM   3734  C CA  . CYS B 2 148 ? -28.499 -33.228 -90.341  1.00 98.83  ? 148 CYS B CA  1 
ATOM   3735  C C   . CYS B 2 148 ? -28.787 -31.969 -89.531  1.00 98.86  ? 148 CYS B C   1 
ATOM   3736  O O   . CYS B 2 148 ? -27.859 -31.296 -89.067  1.00 98.66  ? 148 CYS B O   1 
ATOM   3737  C CB  . CYS B 2 148 ? -28.497 -32.933 -91.843  1.00 99.09  ? 148 CYS B CB  1 
ATOM   3738  S SG  . CYS B 2 148 ? -27.932 -31.281 -92.295  1.00 119.93 ? 148 CYS B SG  1 
ATOM   3739  N N   . MET B 2 149 ? -30.071 -31.641 -89.344  1.00 93.68  ? 149 MET B N   1 
ATOM   3740  C CA  . MET B 2 149 ? -30.438 -30.516 -88.488  1.00 91.47  ? 149 MET B CA  1 
ATOM   3741  C C   . MET B 2 149 ? -30.018 -30.758 -87.045  1.00 91.51  ? 149 MET B C   1 
ATOM   3742  O O   . MET B 2 149 ? -29.478 -29.860 -86.388  1.00 80.88  ? 149 MET B O   1 
ATOM   3743  C CB  . MET B 2 149 ? -31.945 -30.264 -88.562  1.00 86.75  ? 149 MET B CB  1 
ATOM   3744  C CG  . MET B 2 149 ? -32.420 -29.632 -89.856  1.00 92.31  ? 149 MET B CG  1 
ATOM   3745  S SD  . MET B 2 149 ? -31.610 -28.055 -90.185  1.00 90.86  ? 149 MET B SD  1 
ATOM   3746  C CE  . MET B 2 149 ? -32.747 -27.336 -91.367  1.00 92.93  ? 149 MET B CE  1 
ATOM   3747  N N   . GLU B 2 150 ? -30.266 -31.965 -86.530  1.00 96.88  ? 150 GLU B N   1 
ATOM   3748  C CA  . GLU B 2 150 ? -29.818 -32.298 -85.182  1.00 96.04  ? 150 GLU B CA  1 
ATOM   3749  C C   . GLU B 2 150 ? -28.300 -32.354 -85.104  1.00 95.54  ? 150 GLU B C   1 
ATOM   3750  O O   . GLU B 2 150 ? -27.721 -32.012 -84.067  1.00 101.81 ? 150 GLU B O   1 
ATOM   3751  C CB  . GLU B 2 150 ? -30.429 -33.628 -84.736  1.00 93.95  ? 150 GLU B CB  1 
ATOM   3752  C CG  . GLU B 2 150 ? -30.043 -34.066 -83.326  1.00 93.91  ? 150 GLU B CG  1 
ATOM   3753  C CD  . GLU B 2 150 ? -30.740 -33.268 -82.234  1.00 105.28 ? 150 GLU B CD  1 
ATOM   3754  O OE1 . GLU B 2 150 ? -31.472 -32.307 -82.556  1.00 101.32 ? 150 GLU B OE1 1 
ATOM   3755  O OE2 . GLU B 2 150 ? -30.558 -33.610 -81.047  1.00 110.30 ? 150 GLU B OE2 1 
ATOM   3756  N N   . SER B 2 151 ? -27.645 -32.775 -86.188  1.00 96.76  ? 151 SER B N   1 
ATOM   3757  C CA  . SER B 2 151 ? -26.187 -32.758 -86.235  1.00 101.09 ? 151 SER B CA  1 
ATOM   3758  C C   . SER B 2 151 ? -25.644 -31.349 -86.025  1.00 94.53  ? 151 SER B C   1 
ATOM   3759  O O   . SER B 2 151 ? -24.589 -31.167 -85.405  1.00 96.39  ? 151 SER B O   1 
ATOM   3760  C CB  . SER B 2 151 ? -25.709 -33.331 -87.568  1.00 97.92  ? 151 SER B CB  1 
ATOM   3761  O OG  . SER B 2 151 ? -24.486 -32.748 -87.967  1.00 104.11 ? 151 SER B OG  1 
ATOM   3762  N N   . VAL B 2 152 ? -26.349 -30.340 -86.538  1.00 98.01  ? 152 VAL B N   1 
ATOM   3763  C CA  . VAL B 2 152 ? -25.953 -28.957 -86.292  1.00 96.57  ? 152 VAL B CA  1 
ATOM   3764  C C   . VAL B 2 152 ? -26.206 -28.579 -84.837  1.00 98.84  ? 152 VAL B C   1 
ATOM   3765  O O   . VAL B 2 152 ? -25.400 -27.879 -84.213  1.00 99.39  ? 152 VAL B O   1 
ATOM   3766  C CB  . VAL B 2 152 ? -26.690 -28.012 -87.258  1.00 89.49  ? 152 VAL B CB  1 
ATOM   3767  C CG1 . VAL B 2 152 ? -26.263 -26.572 -87.023  1.00 98.39  ? 152 VAL B CG1 1 
ATOM   3768  C CG2 . VAL B 2 152 ? -26.432 -28.419 -88.699  1.00 103.97 ? 152 VAL B CG2 1 
ATOM   3769  N N   . ARG B 2 153 ? -27.326 -29.038 -84.272  1.00 97.41  ? 153 ARG B N   1 
ATOM   3770  C CA  . ARG B 2 153 ? -27.704 -28.616 -82.927  1.00 98.05  ? 153 ARG B CA  1 
ATOM   3771  C C   . ARG B 2 153 ? -26.815 -29.251 -81.862  1.00 98.18  ? 153 ARG B C   1 
ATOM   3772  O O   . ARG B 2 153 ? -26.494 -28.607 -80.857  1.00 86.58  ? 153 ARG B O   1 
ATOM   3773  C CB  . ARG B 2 153 ? -29.177 -28.935 -82.672  1.00 93.90  ? 153 ARG B CB  1 
ATOM   3774  C CG  . ARG B 2 153 ? -30.131 -28.161 -83.572  1.00 84.99  ? 153 ARG B CG  1 
ATOM   3775  C CD  . ARG B 2 153 ? -31.559 -28.211 -83.052  1.00 84.17  ? 153 ARG B CD  1 
ATOM   3776  N NE  . ARG B 2 153 ? -32.137 -29.547 -83.136  1.00 84.33  ? 153 ARG B NE  1 
ATOM   3777  C CZ  . ARG B 2 153 ? -32.986 -29.938 -84.076  1.00 96.45  ? 153 ARG B CZ  1 
ATOM   3778  N NH1 . ARG B 2 153 ? -33.388 -29.115 -85.031  1.00 97.29  ? 153 ARG B NH1 1 
ATOM   3779  N NH2 . ARG B 2 153 ? -33.447 -31.186 -84.056  1.00 98.06  ? 153 ARG B NH2 1 
ATOM   3780  N N   . ASN B 2 154 ? -26.409 -30.506 -82.054  1.00 96.35  ? 154 ASN B N   1 
ATOM   3781  C CA  . ASN B 2 154 ? -25.513 -31.168 -81.113  1.00 91.23  ? 154 ASN B CA  1 
ATOM   3782  C C   . ASN B 2 154 ? -24.041 -30.996 -81.479  1.00 96.92  ? 154 ASN B C   1 
ATOM   3783  O O   . ASN B 2 154 ? -23.178 -31.595 -80.830  1.00 94.14  ? 154 ASN B O   1 
ATOM   3784  C CB  . ASN B 2 154 ? -25.866 -32.658 -80.980  1.00 84.45  ? 154 ASN B CB  1 
ATOM   3785  C CG  . ASN B 2 154 ? -25.792 -33.415 -82.298  1.00 97.23  ? 154 ASN B CG  1 
ATOM   3786  O OD1 . ASN B 2 154 ? -25.033 -33.061 -83.200  1.00 99.01  ? 154 ASN B OD1 1 
ATOM   3787  N ND2 . ASN B 2 154 ? -26.585 -34.476 -82.407  1.00 90.04  ? 154 ASN B ND2 1 
ATOM   3788  N N   . GLY B 2 155 ? -23.742 -30.197 -82.498  1.00 101.30 ? 155 GLY B N   1 
ATOM   3789  C CA  . GLY B 2 155 ? -22.368 -29.884 -82.857  1.00 102.58 ? 155 GLY B CA  1 
ATOM   3790  C C   . GLY B 2 155 ? -21.546 -31.039 -83.388  1.00 108.26 ? 155 GLY B C   1 
ATOM   3791  O O   . GLY B 2 155 ? -20.381 -31.193 -83.000  1.00 109.99 ? 155 GLY B O   1 
ATOM   3792  N N   . THR B 2 156 ? -22.121 -31.858 -84.267  1.00 108.94 ? 156 THR B N   1 
ATOM   3793  C CA  . THR B 2 156 ? -21.416 -32.963 -84.913  1.00 105.29 ? 156 THR B CA  1 
ATOM   3794  C C   . THR B 2 156 ? -21.598 -32.891 -86.424  1.00 109.87 ? 156 THR B C   1 
ATOM   3795  O O   . THR B 2 156 ? -21.887 -33.888 -87.090  1.00 112.15 ? 156 THR B O   1 
ATOM   3796  C CB  . THR B 2 156 ? -21.894 -34.321 -84.399  1.00 105.58 ? 156 THR B CB  1 
ATOM   3797  O OG1 . THR B 2 156 ? -23.186 -34.614 -84.947  1.00 107.57 ? 156 THR B OG1 1 
ATOM   3798  C CG2 . THR B 2 156 ? -21.982 -34.329 -82.877  1.00 97.18  ? 156 THR B CG2 1 
ATOM   3799  N N   . TYR B 2 157 ? -21.428 -31.698 -86.992  1.00 108.26 ? 157 TYR B N   1 
ATOM   3800  C CA  . TYR B 2 157 ? -21.690 -31.500 -88.412  1.00 110.95 ? 157 TYR B CA  1 
ATOM   3801  C C   . TYR B 2 157 ? -20.560 -32.087 -89.251  1.00 113.33 ? 157 TYR B C   1 
ATOM   3802  O O   . TYR B 2 157 ? -19.385 -31.814 -89.003  1.00 113.60 ? 157 TYR B O   1 
ATOM   3803  C CB  . TYR B 2 157 ? -21.870 -30.014 -88.726  1.00 110.67 ? 157 TYR B CB  1 
ATOM   3804  C CG  . TYR B 2 157 ? -22.253 -29.748 -90.165  1.00 107.38 ? 157 TYR B CG  1 
ATOM   3805  C CD1 . TYR B 2 157 ? -21.375 -29.112 -91.032  1.00 113.97 ? 157 TYR B CD1 1 
ATOM   3806  C CD2 . TYR B 2 157 ? -23.489 -30.147 -90.661  1.00 110.03 ? 157 TYR B CD2 1 
ATOM   3807  C CE1 . TYR B 2 157 ? -21.720 -28.870 -92.349  1.00 119.97 ? 157 TYR B CE1 1 
ATOM   3808  C CE2 . TYR B 2 157 ? -23.842 -29.910 -91.977  1.00 107.34 ? 157 TYR B CE2 1 
ATOM   3809  C CZ  . TYR B 2 157 ? -22.955 -29.271 -92.816  1.00 109.86 ? 157 TYR B CZ  1 
ATOM   3810  O OH  . TYR B 2 157 ? -23.302 -29.033 -94.126  1.00 110.54 ? 157 TYR B OH  1 
ATOM   3811  N N   . ASP B 2 158 ? -20.918 -32.892 -90.248  1.00 126.21 ? 158 ASP B N   1 
ATOM   3812  C CA  . ASP B 2 158 ? -19.954 -33.512 -91.157  1.00 129.54 ? 158 ASP B CA  1 
ATOM   3813  C C   . ASP B 2 158 ? -19.855 -32.660 -92.420  1.00 128.46 ? 158 ASP B C   1 
ATOM   3814  O O   . ASP B 2 158 ? -20.706 -32.762 -93.307  1.00 122.80 ? 158 ASP B O   1 
ATOM   3815  C CB  . ASP B 2 158 ? -20.399 -34.932 -91.491  1.00 131.90 ? 158 ASP B CB  1 
ATOM   3816  C CG  . ASP B 2 158 ? -19.357 -35.712 -92.281  1.00 131.90 ? 158 ASP B CG  1 
ATOM   3817  O OD1 . ASP B 2 158 ? -18.752 -35.157 -93.219  1.00 130.60 ? 158 ASP B OD1 1 
ATOM   3818  O OD2 . ASP B 2 158 ? -19.122 -36.893 -91.943  1.00 122.97 ? 158 ASP B OD2 1 
ATOM   3819  N N   . TYR B 2 159 ? -18.821 -31.805 -92.483  1.00 128.34 ? 159 TYR B N   1 
ATOM   3820  C CA  . TYR B 2 159 ? -18.516 -30.986 -93.663  1.00 126.86 ? 159 TYR B CA  1 
ATOM   3821  C C   . TYR B 2 159 ? -18.074 -31.812 -94.877  1.00 134.57 ? 159 TYR B C   1 
ATOM   3822  O O   . TYR B 2 159 ? -18.593 -31.580 -95.989  1.00 133.99 ? 159 TYR B O   1 
ATOM   3823  C CB  . TYR B 2 159 ? -17.480 -29.915 -93.238  1.00 135.04 ? 159 TYR B CB  1 
ATOM   3824  C CG  . TYR B 2 159 ? -17.032 -28.984 -94.375  1.00 137.19 ? 159 TYR B CG  1 
ATOM   3825  C CD1 . TYR B 2 159 ? -16.043 -29.395 -95.308  1.00 141.42 ? 159 TYR B CD1 1 
ATOM   3826  C CD2 . TYR B 2 159 ? -17.531 -27.686 -94.497  1.00 130.44 ? 159 TYR B CD2 1 
ATOM   3827  C CE1 . TYR B 2 159 ? -15.625 -28.537 -96.312  1.00 145.91 ? 159 TYR B CE1 1 
ATOM   3828  C CE2 . TYR B 2 159 ? -17.119 -26.852 -95.518  1.00 133.45 ? 159 TYR B CE2 1 
ATOM   3829  C CZ  . TYR B 2 159 ? -16.182 -27.286 -96.418  1.00 144.31 ? 159 TYR B CZ  1 
ATOM   3830  O OH  . TYR B 2 159 ? -15.859 -26.437 -97.429  1.00 141.72 ? 159 TYR B OH  1 
ATOM   3831  N N   . PRO B 2 160 ? -17.212 -32.823 -94.744  1.00 133.28 ? 160 PRO B N   1 
ATOM   3832  C CA  . PRO B 2 160 ? -16.799 -33.562 -95.938  1.00 131.91 ? 160 PRO B CA  1 
ATOM   3833  C C   . PRO B 2 160 ? -17.959 -34.226 -96.626  1.00 128.08 ? 160 PRO B C   1 
ATOM   3834  O O   . PRO B 2 160 ? -17.952 -34.332 -97.858  1.00 131.25 ? 160 PRO B O   1 
ATOM   3835  C CB  . PRO B 2 160 ? -15.773 -34.567 -95.398  1.00 127.33 ? 160 PRO B CB  1 
ATOM   3836  C CG  . PRO B 2 160 ? -15.200 -33.904 -94.215  1.00 127.25 ? 160 PRO B CG  1 
ATOM   3837  C CD  . PRO B 2 160 ? -16.343 -33.125 -93.597  1.00 124.84 ? 160 PRO B CD  1 
ATOM   3838  N N   . GLN B 2 161 ? -18.990 -34.606 -95.868  1.00 127.22 ? 161 GLN B N   1 
ATOM   3839  C CA  . GLN B 2 161 ? -20.141 -35.277 -96.460  1.00 126.63 ? 161 GLN B CA  1 
ATOM   3840  C C   . GLN B 2 161 ? -20.817 -34.402 -97.506  1.00 128.11 ? 161 GLN B C   1 
ATOM   3841  O O   . GLN B 2 161 ? -21.041 -34.838 -98.640  1.00 132.89 ? 161 GLN B O   1 
ATOM   3842  C CB  . GLN B 2 161 ? -21.140 -35.677 -95.374  1.00 129.17 ? 161 GLN B CB  1 
ATOM   3843  C CG  . GLN B 2 161 ? -20.992 -37.107 -94.880  1.00 137.83 ? 161 GLN B CG  1 
ATOM   3844  C CD  . GLN B 2 161 ? -22.076 -37.496 -93.893  1.00 134.38 ? 161 GLN B CD  1 
ATOM   3845  O OE1 . GLN B 2 161 ? -23.266 -37.320 -94.157  1.00 123.62 ? 161 GLN B OE1 1 
ATOM   3846  N NE2 . GLN B 2 161 ? -21.669 -38.023 -92.743  1.00 128.45 ? 161 GLN B NE2 1 
ATOM   3847  N N   . TYR B 2 162 ? -21.151 -33.164 -97.147  1.00 125.52 ? 162 TYR B N   1 
ATOM   3848  C CA  . TYR B 2 162 ? -21.855 -32.257 -98.043  1.00 128.21 ? 162 TYR B CA  1 
ATOM   3849  C C   . TYR B 2 162 ? -20.928 -31.243 -98.699  1.00 135.01 ? 162 TYR B C   1 
ATOM   3850  O O   . TYR B 2 162 ? -21.410 -30.282 -99.307  1.00 140.53 ? 162 TYR B O   1 
ATOM   3851  C CB  . TYR B 2 162 ? -22.972 -31.530 -97.290  1.00 124.21 ? 162 TYR B CB  1 
ATOM   3852  C CG  . TYR B 2 162 ? -23.879 -32.444 -96.497  1.00 117.75 ? 162 TYR B CG  1 
ATOM   3853  C CD1 . TYR B 2 162 ? -24.992 -33.032 -97.084  1.00 114.72 ? 162 TYR B CD1 1 
ATOM   3854  C CD2 . TYR B 2 162 ? -23.623 -32.716 -95.159  1.00 113.45 ? 162 TYR B CD2 1 
ATOM   3855  C CE1 . TYR B 2 162 ? -25.825 -33.867 -96.359  1.00 110.98 ? 162 TYR B CE1 1 
ATOM   3856  C CE2 . TYR B 2 162 ? -24.448 -33.549 -94.428  1.00 112.04 ? 162 TYR B CE2 1 
ATOM   3857  C CZ  . TYR B 2 162 ? -25.547 -34.122 -95.032  1.00 107.34 ? 162 TYR B CZ  1 
ATOM   3858  O OH  . TYR B 2 162 ? -26.370 -34.951 -94.305  1.00 105.14 ? 162 TYR B OH  1 
ATOM   3859  N N   . SER B 2 163 ? -19.610 -31.433 -98.586  1.00 131.99 ? 163 SER B N   1 
ATOM   3860  C CA  . SER B 2 163 ? -18.668 -30.467 -99.143  1.00 132.34 ? 163 SER B CA  1 
ATOM   3861  C C   . SER B 2 163 ? -18.804 -30.366 -100.658 1.00 131.97 ? 163 SER B C   1 
ATOM   3862  O O   . SER B 2 163 ? -18.800 -29.262 -101.216 1.00 127.16 ? 163 SER B O   1 
ATOM   3863  C CB  . SER B 2 163 ? -17.239 -30.849 -98.758  1.00 129.87 ? 163 SER B CB  1 
ATOM   3864  O OG  . SER B 2 163 ? -16.308 -29.881 -99.208  1.00 131.90 ? 163 SER B OG  1 
ATOM   3865  N N   . GLU B 2 164 ? -18.923 -31.506 -101.340 1.00 136.57 ? 164 GLU B N   1 
ATOM   3866  C CA  . GLU B 2 164 ? -19.048 -31.490 -102.794 1.00 136.47 ? 164 GLU B CA  1 
ATOM   3867  C C   . GLU B 2 164 ? -20.453 -31.100 -103.240 1.00 136.27 ? 164 GLU B C   1 
ATOM   3868  O O   . GLU B 2 164 ? -20.612 -30.403 -104.249 1.00 138.75 ? 164 GLU B O   1 
ATOM   3869  C CB  . GLU B 2 164 ? -18.665 -32.856 -103.368 1.00 135.90 ? 164 GLU B CB  1 
ATOM   3870  C CG  . GLU B 2 164 ? -17.240 -33.293 -103.053 1.00 133.13 ? 164 GLU B CG  1 
ATOM   3871  C CD  . GLU B 2 164 ? -16.191 -32.470 -103.783 1.00 137.88 ? 164 GLU B CD  1 
ATOM   3872  O OE1 . GLU B 2 164 ? -16.540 -31.790 -104.772 1.00 137.28 ? 164 GLU B OE1 1 
ATOM   3873  O OE2 . GLU B 2 164 ? -15.014 -32.507 -103.367 1.00 130.07 ? 164 GLU B OE2 1 
ATOM   3874  N N   . GLU B 2 165 ? -21.480 -31.542 -102.508 1.00 134.92 ? 165 GLU B N   1 
ATOM   3875  C CA  . GLU B 2 165 ? -22.855 -31.242 -102.902 1.00 137.41 ? 165 GLU B CA  1 
ATOM   3876  C C   . GLU B 2 165 ? -23.143 -29.748 -102.828 1.00 144.61 ? 165 GLU B C   1 
ATOM   3877  O O   . GLU B 2 165 ? -23.839 -29.202 -103.692 1.00 141.84 ? 165 GLU B O   1 
ATOM   3878  C CB  . GLU B 2 165 ? -23.841 -32.016 -102.027 1.00 131.73 ? 165 GLU B CB  1 
ATOM   3879  C CG  . GLU B 2 165 ? -23.765 -33.528 -102.166 1.00 133.42 ? 165 GLU B CG  1 
ATOM   3880  C CD  . GLU B 2 165 ? -22.735 -34.152 -101.246 1.00 133.29 ? 165 GLU B CD  1 
ATOM   3881  O OE1 . GLU B 2 165 ? -21.553 -33.749 -101.305 1.00 129.24 ? 165 GLU B OE1 1 
ATOM   3882  O OE2 . GLU B 2 165 ? -23.113 -35.042 -100.456 1.00 128.27 ? 165 GLU B OE2 1 
ATOM   3883  N N   . ALA B 2 166 ? -22.630 -29.073 -101.795 1.00 141.80 ? 166 ALA B N   1 
ATOM   3884  C CA  . ALA B 2 166 ? -22.829 -27.632 -101.687 1.00 140.88 ? 166 ALA B CA  1 
ATOM   3885  C C   . ALA B 2 166 ? -22.153 -26.890 -102.831 1.00 139.37 ? 166 ALA B C   1 
ATOM   3886  O O   . ALA B 2 166 ? -22.627 -25.827 -103.248 1.00 133.27 ? 166 ALA B O   1 
ATOM   3887  C CB  . ALA B 2 166 ? -22.307 -27.128 -100.344 1.00 136.25 ? 166 ALA B CB  1 
ATOM   3888  N N   . ARG B 2 167 ? -21.045 -27.429 -103.343 1.00 140.98 ? 167 ARG B N   1 
ATOM   3889  C CA  . ARG B 2 167 ? -20.419 -26.859 -104.531 1.00 140.42 ? 167 ARG B CA  1 
ATOM   3890  C C   . ARG B 2 167 ? -21.319 -26.994 -105.754 1.00 145.19 ? 167 ARG B C   1 
ATOM   3891  O O   . ARG B 2 167 ? -21.293 -26.131 -106.640 1.00 146.50 ? 167 ARG B O   1 
ATOM   3892  C CB  . ARG B 2 167 ? -19.063 -27.530 -104.766 1.00 135.37 ? 167 ARG B CB  1 
ATOM   3893  C CG  . ARG B 2 167 ? -18.387 -27.200 -106.089 1.00 140.65 ? 167 ARG B CG  1 
ATOM   3894  C CD  . ARG B 2 167 ? -18.563 -28.333 -107.091 1.00 149.90 ? 167 ARG B CD  1 
ATOM   3895  N NE  . ARG B 2 167 ? -17.757 -28.140 -108.290 1.00 151.25 ? 167 ARG B NE  1 
ATOM   3896  C CZ  . ARG B 2 167 ? -16.541 -28.640 -108.462 1.00 154.98 ? 167 ARG B CZ  1 
ATOM   3897  N NH1 . ARG B 2 167 ? -15.956 -29.373 -107.529 1.00 145.75 ? 167 ARG B NH1 1 
ATOM   3898  N NH2 . ARG B 2 167 ? -15.897 -28.401 -109.601 1.00 161.19 ? 167 ARG B NH2 1 
ATOM   3899  N N   . LEU B 2 168 ? -22.123 -28.059 -105.817 1.00 147.50 ? 168 LEU B N   1 
ATOM   3900  C CA  . LEU B 2 168 ? -23.006 -28.261 -106.962 1.00 149.34 ? 168 LEU B CA  1 
ATOM   3901  C C   . LEU B 2 168 ? -24.133 -27.236 -107.004 1.00 149.19 ? 168 LEU B C   1 
ATOM   3902  O O   . LEU B 2 168 ? -24.639 -26.922 -108.086 1.00 146.61 ? 168 LEU B O   1 
ATOM   3903  C CB  . LEU B 2 168 ? -23.579 -29.679 -106.940 1.00 148.38 ? 168 LEU B CB  1 
ATOM   3904  C CG  . LEU B 2 168 ? -22.588 -30.816 -107.198 1.00 149.50 ? 168 LEU B CG  1 
ATOM   3905  C CD1 . LEU B 2 168 ? -23.272 -32.167 -107.056 1.00 148.39 ? 168 LEU B CD1 1 
ATOM   3906  C CD2 . LEU B 2 168 ? -21.958 -30.675 -108.576 1.00 140.45 ? 168 LEU B CD2 1 
ATOM   3907  N N   . LYS B 2 169 ? -24.556 -26.723 -105.852 1.00 145.80 ? 169 LYS B N   1 
ATOM   3908  C CA  . LYS B 2 169 ? -25.565 -25.672 -105.814 1.00 141.48 ? 169 LYS B CA  1 
ATOM   3909  C C   . LYS B 2 169 ? -24.966 -24.274 -105.734 1.00 143.76 ? 169 LYS B C   1 
ATOM   3910  O O   . LYS B 2 169 ? -25.697 -23.294 -105.911 1.00 143.58 ? 169 LYS B O   1 
ATOM   3911  C CB  . LYS B 2 169 ? -26.510 -25.888 -104.626 1.00 132.04 ? 169 LYS B CB  1 
ATOM   3912  C CG  . LYS B 2 169 ? -27.724 -26.753 -104.932 1.00 123.65 ? 169 LYS B CG  1 
ATOM   3913  C CD  . LYS B 2 169 ? -28.874 -25.920 -105.479 1.00 111.67 ? 169 LYS B CD  1 
ATOM   3914  C CE  . LYS B 2 169 ? -30.136 -26.755 -105.634 1.00 105.53 ? 169 LYS B CE  1 
ATOM   3915  N NZ  . LYS B 2 169 ? -31.322 -25.921 -105.974 1.00 101.31 ? 169 LYS B NZ  1 
ATOM   3916  N N   . ARG B 2 170 ? -23.663 -24.161 -105.476 1.00 144.89 ? 170 ARG B N   1 
ATOM   3917  C CA  . ARG B 2 170 ? -23.033 -22.855 -105.313 1.00 147.12 ? 170 ARG B CA  1 
ATOM   3918  C C   . ARG B 2 170 ? -22.651 -22.244 -106.657 1.00 157.33 ? 170 ARG B C   1 
ATOM   3919  O O   . ARG B 2 170 ? -23.151 -21.179 -107.034 1.00 160.08 ? 170 ARG B O   1 
ATOM   3920  C CB  . ARG B 2 170 ? -21.801 -22.988 -104.415 1.00 142.93 ? 170 ARG B CB  1 
ATOM   3921  C CG  . ARG B 2 170 ? -21.057 -21.694 -104.145 1.00 134.47 ? 170 ARG B CG  1 
ATOM   3922  C CD  . ARG B 2 170 ? -19.759 -21.997 -103.422 1.00 126.58 ? 170 ARG B CD  1 
ATOM   3923  N NE  . ARG B 2 170 ? -19.955 -23.029 -102.411 1.00 129.99 ? 170 ARG B NE  1 
ATOM   3924  C CZ  . ARG B 2 170 ? -18.976 -23.710 -101.832 1.00 139.31 ? 170 ARG B CZ  1 
ATOM   3925  N NH1 . ARG B 2 170 ? -17.707 -23.492 -102.136 1.00 138.96 ? 170 ARG B NH1 1 
ATOM   3926  N NH2 . ARG B 2 170 ? -19.279 -24.640 -100.930 1.00 132.63 ? 170 ARG B NH2 1 
ATOM   3927  N N   . GLU B 2 171 ? -21.764 -22.911 -107.396 1.00 158.31 ? 171 GLU B N   1 
ATOM   3928  C CA  . GLU B 2 171 ? -21.234 -22.357 -108.634 1.00 158.21 ? 171 GLU B CA  1 
ATOM   3929  C C   . GLU B 2 171 ? -22.006 -22.797 -109.870 1.00 159.01 ? 171 GLU B C   1 
ATOM   3930  O O   . GLU B 2 171 ? -21.965 -22.095 -110.888 1.00 159.56 ? 171 GLU B O   1 
ATOM   3931  C CB  . GLU B 2 171 ? -19.759 -22.741 -108.795 1.00 154.11 ? 171 GLU B CB  1 
ATOM   3932  C CG  . GLU B 2 171 ? -19.515 -24.231 -108.970 1.00 153.74 ? 171 GLU B CG  1 
ATOM   3933  C CD  . GLU B 2 171 ? -18.041 -24.572 -109.062 1.00 157.62 ? 171 GLU B CD  1 
ATOM   3934  O OE1 . GLU B 2 171 ? -17.237 -23.937 -108.348 1.00 152.85 ? 171 GLU B OE1 1 
ATOM   3935  O OE2 . GLU B 2 171 ? -17.686 -25.470 -109.854 1.00 163.51 ? 171 GLU B OE2 1 
ATOM   3936  N N   . GLU B 2 172 ? -22.706 -23.930 -109.812 1.00 160.88 ? 172 GLU B N   1 
ATOM   3937  C CA  . GLU B 2 172 ? -23.473 -24.393 -110.961 1.00 168.90 ? 172 GLU B CA  1 
ATOM   3938  C C   . GLU B 2 172 ? -24.796 -23.655 -111.122 1.00 161.80 ? 172 GLU B C   1 
ATOM   3939  O O   . GLU B 2 172 ? -25.471 -23.843 -112.140 1.00 163.41 ? 172 GLU B O   1 
ATOM   3940  C CB  . GLU B 2 172 ? -23.732 -25.899 -110.854 1.00 171.66 ? 172 GLU B CB  1 
ATOM   3941  C CG  . GLU B 2 172 ? -22.513 -26.732 -110.459 1.00 168.37 ? 172 GLU B CG  1 
ATOM   3942  C CD  . GLU B 2 172 ? -21.631 -27.108 -111.637 1.00 163.00 ? 172 GLU B CD  1 
ATOM   3943  O OE1 . GLU B 2 172 ? -21.710 -26.437 -112.688 1.00 170.56 ? 172 GLU B OE1 1 
ATOM   3944  O OE2 . GLU B 2 172 ? -20.860 -28.083 -111.513 1.00 152.70 ? 172 GLU B OE2 1 
ATOM   3945  N N   . ILE B 2 173 ? -25.182 -22.832 -110.150 1.00 155.80 ? 173 ILE B N   1 
ATOM   3946  C CA  . ILE B 2 173 ? -26.366 -21.987 -110.250 1.00 158.48 ? 173 ILE B CA  1 
ATOM   3947  C C   . ILE B 2 173 ? -25.865 -20.581 -110.554 1.00 160.80 ? 173 ILE B C   1 
ATOM   3948  O O   . ILE B 2 173 ? -25.329 -19.892 -109.681 1.00 157.14 ? 173 ILE B O   1 
ATOM   3949  C CB  . ILE B 2 173 ? -27.213 -22.036 -108.975 1.00 148.53 ? 173 ILE B CB  1 
ATOM   3950  C CG1 . ILE B 2 173 ? -27.859 -23.416 -108.819 1.00 147.50 ? 173 ILE B CG1 1 
ATOM   3951  C CG2 . ILE B 2 173 ? -28.282 -20.953 -108.998 1.00 135.46 ? 173 ILE B CG2 1 
ATOM   3952  C CD1 . ILE B 2 173 ? -28.842 -23.759 -109.921 1.00 123.59 ? 173 ILE B CD1 1 
ATOM   3953  N N   . SER B 2 174 ? -26.038 -20.148 -111.798 1.00 156.63 ? 174 SER B N   1 
ATOM   3954  C CA  . SER B 2 174 ? -25.588 -18.827 -112.220 1.00 143.42 ? 174 SER B CA  1 
ATOM   3955  C C   . SER B 2 174 ? -26.748 -18.010 -112.780 1.00 140.19 ? 174 SER B C   1 
ATOM   3956  O O   . SER B 2 174 ? -27.432 -18.442 -113.709 1.00 133.67 ? 174 SER B O   1 
ATOM   3957  C CB  . SER B 2 174 ? -24.473 -18.945 -113.263 1.00 138.45 ? 174 SER B CB  1 
ATOM   3958  O OG  . SER B 2 174 ? -23.342 -19.607 -112.725 1.00 141.75 ? 174 SER B OG  1 
ATOM   3959  N N   . GLY C 1 4   ? -1.750  -28.236 -95.814  1.00 193.02 ? 10  GLY C N   1 
ATOM   3960  C CA  . GLY C 1 4   ? -1.098  -26.944 -95.716  1.00 192.17 ? 10  GLY C CA  1 
ATOM   3961  C C   . GLY C 1 4   ? -0.580  -26.635 -94.325  1.00 206.32 ? 10  GLY C C   1 
ATOM   3962  O O   . GLY C 1 4   ? -0.743  -27.433 -93.401  1.00 205.70 ? 10  GLY C O   1 
ATOM   3963  N N   . ASP C 1 5   ? 0.046   -25.471 -94.176  1.00 211.52 ? 11  ASP C N   1 
ATOM   3964  C CA  . ASP C 1 5   ? 0.592   -25.059 -92.894  1.00 211.14 ? 11  ASP C CA  1 
ATOM   3965  C C   . ASP C 1 5   ? -0.524  -24.566 -91.973  1.00 208.51 ? 11  ASP C C   1 
ATOM   3966  O O   . ASP C 1 5   ? -1.660  -24.331 -92.394  1.00 201.69 ? 11  ASP C O   1 
ATOM   3967  C CB  . ASP C 1 5   ? 1.658   -23.984 -93.092  1.00 200.09 ? 11  ASP C CB  1 
ATOM   3968  C CG  . ASP C 1 5   ? 2.750   -24.424 -94.047  1.00 191.47 ? 11  ASP C CG  1 
ATOM   3969  O OD1 . ASP C 1 5   ? 2.503   -25.349 -94.848  1.00 196.07 ? 11  ASP C OD1 1 
ATOM   3970  O OD2 . ASP C 1 5   ? 3.859   -23.857 -93.990  1.00 184.12 ? 11  ASP C OD2 1 
ATOM   3971  N N   . GLN C 1 6   ? -0.191  -24.415 -90.692  1.00 204.71 ? 12  GLN C N   1 
ATOM   3972  C CA  . GLN C 1 6   ? -1.197  -24.162 -89.672  1.00 194.91 ? 12  GLN C CA  1 
ATOM   3973  C C   . GLN C 1 6   ? -0.683  -23.160 -88.648  1.00 194.25 ? 12  GLN C C   1 
ATOM   3974  O O   . GLN C 1 6   ? 0.508   -23.126 -88.328  1.00 190.96 ? 12  GLN C O   1 
ATOM   3975  C CB  . GLN C 1 6   ? -1.605  -25.471 -88.980  1.00 185.94 ? 12  GLN C CB  1 
ATOM   3976  C CG  . GLN C 1 6   ? -2.874  -25.387 -88.155  1.00 179.70 ? 12  GLN C CG  1 
ATOM   3977  C CD  . GLN C 1 6   ? -3.647  -26.691 -88.160  1.00 178.60 ? 12  GLN C CD  1 
ATOM   3978  O OE1 . GLN C 1 6   ? -3.881  -27.280 -89.216  1.00 185.36 ? 12  GLN C OE1 1 
ATOM   3979  N NE2 . GLN C 1 6   ? -4.043  -27.152 -86.980  1.00 173.29 ? 12  GLN C NE2 1 
ATOM   3980  N N   . ILE C 1 7   ? -1.602  -22.338 -88.143  1.00 194.71 ? 13  ILE C N   1 
ATOM   3981  C CA  . ILE C 1 7   ? -1.338  -21.403 -87.054  1.00 179.24 ? 13  ILE C CA  1 
ATOM   3982  C C   . ILE C 1 7   ? -2.574  -21.365 -86.163  1.00 172.57 ? 13  ILE C C   1 
ATOM   3983  O O   . ILE C 1 7   ? -3.707  -21.398 -86.656  1.00 173.99 ? 13  ILE C O   1 
ATOM   3984  C CB  . ILE C 1 7   ? -0.971  -19.997 -87.584  1.00 171.09 ? 13  ILE C CB  1 
ATOM   3985  C CG1 . ILE C 1 7   ? -0.546  -19.074 -86.439  1.00 159.77 ? 13  ILE C CG1 1 
ATOM   3986  C CG2 . ILE C 1 7   ? -2.120  -19.389 -88.383  1.00 173.44 ? 13  ILE C CG2 1 
ATOM   3987  C CD1 . ILE C 1 7   ? 0.805   -19.417 -85.850  1.00 157.15 ? 13  ILE C CD1 1 
ATOM   3988  N N   . CYS C 1 8   ? -2.361  -21.319 -84.850  1.00 170.30 ? 14  CYS C N   1 
ATOM   3989  C CA  . CYS C 1 8   ? -3.446  -21.405 -83.881  1.00 164.69 ? 14  CYS C CA  1 
ATOM   3990  C C   . CYS C 1 8   ? -3.443  -20.197 -82.949  1.00 159.37 ? 14  CYS C C   1 
ATOM   3991  O O   . CYS C 1 8   ? -2.544  -19.354 -82.978  1.00 161.81 ? 14  CYS C O   1 
ATOM   3992  C CB  . CYS C 1 8   ? -3.349  -22.694 -83.053  1.00 157.79 ? 14  CYS C CB  1 
ATOM   3993  S SG  . CYS C 1 8   ? -3.576  -24.232 -83.975  1.00 164.65 ? 14  CYS C SG  1 
ATOM   3994  N N   . ILE C 1 9   ? -4.484  -20.128 -82.120  1.00 149.89 ? 15  ILE C N   1 
ATOM   3995  C CA  . ILE C 1 9   ? -4.625  -19.119 -81.075  1.00 141.33 ? 15  ILE C CA  1 
ATOM   3996  C C   . ILE C 1 9   ? -4.957  -19.837 -79.774  1.00 137.00 ? 15  ILE C C   1 
ATOM   3997  O O   . ILE C 1 9   ? -5.817  -20.724 -79.754  1.00 127.00 ? 15  ILE C O   1 
ATOM   3998  C CB  . ILE C 1 9   ? -5.717  -18.085 -81.416  1.00 134.59 ? 15  ILE C CB  1 
ATOM   3999  C CG1 . ILE C 1 9   ? -5.392  -17.360 -82.725  1.00 135.49 ? 15  ILE C CG1 1 
ATOM   4000  C CG2 . ILE C 1 9   ? -5.881  -17.082 -80.282  1.00 133.03 ? 15  ILE C CG2 1 
ATOM   4001  C CD1 . ILE C 1 9   ? -4.341  -16.284 -82.587  1.00 128.19 ? 15  ILE C CD1 1 
ATOM   4002  N N   . GLY C 1 10  ? -4.276  -19.461 -78.693  1.00 137.35 ? 16  GLY C N   1 
ATOM   4003  C CA  . GLY C 1 10  ? -4.502  -20.095 -77.408  1.00 133.68 ? 16  GLY C CA  1 
ATOM   4004  C C   . GLY C 1 10  ? -4.027  -19.208 -76.278  1.00 134.04 ? 16  GLY C C   1 
ATOM   4005  O O   . GLY C 1 10  ? -3.510  -18.110 -76.496  1.00 138.77 ? 16  GLY C O   1 
ATOM   4006  N N   . TYR C 1 11  ? -4.201  -19.705 -75.054  1.00 132.22 ? 17  TYR C N   1 
ATOM   4007  C CA  . TYR C 1 11  ? -3.937  -18.908 -73.865  1.00 134.08 ? 17  TYR C CA  1 
ATOM   4008  C C   . TYR C 1 11  ? -3.248  -19.747 -72.795  1.00 131.90 ? 17  TYR C C   1 
ATOM   4009  O O   . TYR C 1 11  ? -3.152  -20.974 -72.889  1.00 127.03 ? 17  TYR C O   1 
ATOM   4010  C CB  . TYR C 1 11  ? -5.227  -18.285 -73.317  1.00 131.76 ? 17  TYR C CB  1 
ATOM   4011  C CG  . TYR C 1 11  ? -6.366  -19.263 -73.154  1.00 128.12 ? 17  TYR C CG  1 
ATOM   4012  C CD1 . TYR C 1 11  ? -6.518  -19.992 -71.982  1.00 129.68 ? 17  TYR C CD1 1 
ATOM   4013  C CD2 . TYR C 1 11  ? -7.293  -19.452 -74.169  1.00 129.57 ? 17  TYR C CD2 1 
ATOM   4014  C CE1 . TYR C 1 11  ? -7.559  -20.885 -71.827  1.00 133.33 ? 17  TYR C CE1 1 
ATOM   4015  C CE2 . TYR C 1 11  ? -8.338  -20.343 -74.024  1.00 140.49 ? 17  TYR C CE2 1 
ATOM   4016  C CZ  . TYR C 1 11  ? -8.466  -21.057 -72.851  1.00 138.73 ? 17  TYR C CZ  1 
ATOM   4017  O OH  . TYR C 1 11  ? -9.504  -21.946 -72.699  1.00 137.99 ? 17  TYR C OH  1 
ATOM   4018  N N   . HIS C 1 12  ? -2.771  -19.049 -71.764  1.00 124.13 ? 18  HIS C N   1 
ATOM   4019  C CA  . HIS C 1 12  ? -1.972  -19.652 -70.704  1.00 112.21 ? 18  HIS C CA  1 
ATOM   4020  C C   . HIS C 1 12  ? -2.810  -20.583 -69.833  1.00 115.49 ? 18  HIS C C   1 
ATOM   4021  O O   . HIS C 1 12  ? -3.951  -20.274 -69.478  1.00 121.66 ? 18  HIS C O   1 
ATOM   4022  C CB  . HIS C 1 12  ? -1.352  -18.543 -69.844  1.00 122.29 ? 18  HIS C CB  1 
ATOM   4023  C CG  . HIS C 1 12  ? -0.277  -19.001 -68.900  1.00 134.01 ? 18  HIS C CG  1 
ATOM   4024  N ND1 . HIS C 1 12  ? -0.178  -20.295 -68.435  1.00 128.29 ? 18  HIS C ND1 1 
ATOM   4025  C CD2 . HIS C 1 12  ? 0.742   -18.320 -68.323  1.00 134.16 ? 18  HIS C CD2 1 
ATOM   4026  C CE1 . HIS C 1 12  ? 0.856   -20.393 -67.618  1.00 123.34 ? 18  HIS C CE1 1 
ATOM   4027  N NE2 . HIS C 1 12  ? 1.432   -19.208 -67.535  1.00 127.94 ? 18  HIS C NE2 1 
ATOM   4028  N N   . ALA C 1 13  ? -2.234  -21.737 -69.502  1.00 107.98 ? 19  ALA C N   1 
ATOM   4029  C CA  . ALA C 1 13  ? -2.698  -22.577 -68.409  1.00 120.43 ? 19  ALA C CA  1 
ATOM   4030  C C   . ALA C 1 13  ? -1.483  -23.195 -67.730  1.00 125.18 ? 19  ALA C C   1 
ATOM   4031  O O   . ALA C 1 13  ? -0.463  -23.451 -68.374  1.00 133.79 ? 19  ALA C O   1 
ATOM   4032  C CB  . ALA C 1 13  ? -3.656  -23.673 -68.894  1.00 123.89 ? 19  ALA C CB  1 
ATOM   4033  N N   . ASN C 1 14  ? -1.591  -23.426 -66.426  1.00 110.52 ? 20  ASN C N   1 
ATOM   4034  C CA  . ASN C 1 14  ? -0.504  -24.064 -65.687  1.00 114.13 ? 20  ASN C CA  1 
ATOM   4035  C C   . ASN C 1 14  ? -1.110  -24.902 -64.565  1.00 120.00 ? 20  ASN C C   1 
ATOM   4036  O O   . ASN C 1 14  ? -2.312  -25.189 -64.565  1.00 117.29 ? 20  ASN C O   1 
ATOM   4037  C CB  . ASN C 1 14  ? 0.516   -23.017 -65.192  1.00 116.69 ? 20  ASN C CB  1 
ATOM   4038  C CG  . ASN C 1 14  ? -0.017  -22.127 -64.067  1.00 125.20 ? 20  ASN C CG  1 
ATOM   4039  O OD1 . ASN C 1 14  ? -0.685  -22.587 -63.142  1.00 116.07 ? 20  ASN C OD1 1 
ATOM   4040  N ND2 . ASN C 1 14  ? 0.307   -20.842 -64.139  1.00 119.99 ? 20  ASN C ND2 1 
ATOM   4041  N N   . ASN C 1 15  ? -0.273  -25.297 -63.606  1.00 125.98 ? 21  ASN C N   1 
ATOM   4042  C CA  . ASN C 1 15  ? -0.699  -26.121 -62.476  1.00 129.72 ? 21  ASN C CA  1 
ATOM   4043  C C   . ASN C 1 15  ? -1.009  -25.202 -61.297  1.00 132.87 ? 21  ASN C C   1 
ATOM   4044  O O   . ASN C 1 15  ? -0.221  -25.048 -60.363  1.00 134.72 ? 21  ASN C O   1 
ATOM   4045  C CB  . ASN C 1 15  ? 0.376   -27.148 -62.129  1.00 135.92 ? 21  ASN C CB  1 
ATOM   4046  C CG  . ASN C 1 15  ? 1.027   -27.751 -63.360  1.00 137.88 ? 21  ASN C CG  1 
ATOM   4047  O OD1 . ASN C 1 15  ? 0.497   -28.682 -63.967  1.00 126.12 ? 21  ASN C OD1 1 
ATOM   4048  N ND2 . ASN C 1 15  ? 2.187   -27.221 -63.734  1.00 130.72 ? 21  ASN C ND2 1 
ATOM   4049  N N   . SER C 1 16  ? -2.186  -24.582 -61.350  1.00 130.61 ? 22  SER C N   1 
ATOM   4050  C CA  . SER C 1 16  ? -2.654  -23.680 -60.306  1.00 121.07 ? 22  SER C CA  1 
ATOM   4051  C C   . SER C 1 16  ? -4.004  -24.161 -59.797  1.00 120.50 ? 22  SER C C   1 
ATOM   4052  O O   . SER C 1 16  ? -4.888  -24.493 -60.593  1.00 128.01 ? 22  SER C O   1 
ATOM   4053  C CB  . SER C 1 16  ? -2.764  -22.243 -60.823  1.00 113.81 ? 22  SER C CB  1 
ATOM   4054  O OG  . SER C 1 16  ? -3.170  -21.360 -59.792  1.00 112.27 ? 22  SER C OG  1 
ATOM   4055  N N   . THR C 1 17  ? -4.157  -24.201 -58.474  1.00 117.20 ? 23  THR C N   1 
ATOM   4056  C CA  . THR C 1 17  ? -5.400  -24.620 -57.839  1.00 118.40 ? 23  THR C CA  1 
ATOM   4057  C C   . THR C 1 17  ? -6.149  -23.463 -57.189  1.00 116.64 ? 23  THR C C   1 
ATOM   4058  O O   . THR C 1 17  ? -7.118  -23.698 -56.459  1.00 104.91 ? 23  THR C O   1 
ATOM   4059  C CB  . THR C 1 17  ? -5.124  -25.711 -56.800  1.00 112.58 ? 23  THR C CB  1 
ATOM   4060  O OG1 . THR C 1 17  ? -4.001  -25.334 -55.993  1.00 109.28 ? 23  THR C OG1 1 
ATOM   4061  C CG2 . THR C 1 17  ? -4.834  -27.039 -57.484  1.00 106.51 ? 23  THR C CG2 1 
ATOM   4062  N N   . GLU C 1 18  ? -5.723  -22.224 -57.430  1.00 114.29 ? 24  GLU C N   1 
ATOM   4063  C CA  . GLU C 1 18  ? -6.390  -21.071 -56.837  1.00 113.72 ? 24  GLU C CA  1 
ATOM   4064  C C   . GLU C 1 18  ? -7.827  -20.970 -57.335  1.00 111.86 ? 24  GLU C C   1 
ATOM   4065  O O   . GLU C 1 18  ? -8.087  -21.050 -58.538  1.00 112.85 ? 24  GLU C O   1 
ATOM   4066  C CB  . GLU C 1 18  ? -5.624  -19.791 -57.171  1.00 118.68 ? 24  GLU C CB  1 
ATOM   4067  C CG  . GLU C 1 18  ? -4.211  -19.744 -56.611  1.00 123.24 ? 24  GLU C CG  1 
ATOM   4068  C CD  . GLU C 1 18  ? -3.437  -18.528 -57.084  1.00 125.63 ? 24  GLU C CD  1 
ATOM   4069  O OE1 . GLU C 1 18  ? -3.897  -17.861 -58.034  1.00 123.29 ? 24  GLU C OE1 1 
ATOM   4070  O OE2 . GLU C 1 18  ? -2.367  -18.239 -56.506  1.00 120.36 ? 24  GLU C OE2 1 
ATOM   4071  N N   . GLN C 1 19  ? -8.759  -20.789 -56.403  1.00 104.72 ? 25  GLN C N   1 
ATOM   4072  C CA  . GLN C 1 19  ? -10.178 -20.686 -56.714  1.00 101.03 ? 25  GLN C CA  1 
ATOM   4073  C C   . GLN C 1 19  ? -10.687 -19.306 -56.326  1.00 100.24 ? 25  GLN C C   1 
ATOM   4074  O O   . GLN C 1 19  ? -10.447 -18.843 -55.206  1.00 102.86 ? 25  GLN C O   1 
ATOM   4075  C CB  . GLN C 1 19  ? -10.990 -21.763 -55.989  1.00 87.31  ? 25  GLN C CB  1 
ATOM   4076  C CG  . GLN C 1 19  ? -10.721 -23.180 -56.461  1.00 90.96  ? 25  GLN C CG  1 
ATOM   4077  C CD  . GLN C 1 19  ? -11.617 -24.194 -55.777  1.00 102.86 ? 25  GLN C CD  1 
ATOM   4078  O OE1 . GLN C 1 19  ? -12.707 -23.863 -55.311  1.00 104.40 ? 25  GLN C OE1 1 
ATOM   4079  N NE2 . GLN C 1 19  ? -11.157 -25.438 -55.709  1.00 104.63 ? 25  GLN C NE2 1 
ATOM   4080  N N   . VAL C 1 20  ? -11.389 -18.659 -57.252  1.00 91.45  ? 26  VAL C N   1 
ATOM   4081  C CA  . VAL C 1 20  ? -12.042 -17.385 -56.998  1.00 84.48  ? 26  VAL C CA  1 
ATOM   4082  C C   . VAL C 1 20  ? -13.534 -17.557 -57.252  1.00 89.93  ? 26  VAL C C   1 
ATOM   4083  O O   . VAL C 1 20  ? -13.977 -18.531 -57.860  1.00 95.02  ? 26  VAL C O   1 
ATOM   4084  C CB  . VAL C 1 20  ? -11.470 -16.244 -57.864  1.00 79.65  ? 26  VAL C CB  1 
ATOM   4085  C CG1 . VAL C 1 20  ? -9.953  -16.312 -57.905  1.00 87.31  ? 26  VAL C CG1 1 
ATOM   4086  C CG2 . VAL C 1 20  ? -12.060 -16.289 -59.266  1.00 72.05  ? 26  VAL C CG2 1 
ATOM   4087  N N   . ASP C 1 21  ? -14.310 -16.595 -56.771  1.00 87.40  ? 27  ASP C N   1 
ATOM   4088  C CA  . ASP C 1 21  ? -15.734 -16.546 -57.046  1.00 74.49  ? 27  ASP C CA  1 
ATOM   4089  C C   . ASP C 1 21  ? -16.046 -15.350 -57.931  1.00 69.76  ? 27  ASP C C   1 
ATOM   4090  O O   . ASP C 1 21  ? -15.340 -14.337 -57.915  1.00 74.10  ? 27  ASP C O   1 
ATOM   4091  C CB  . ASP C 1 21  ? -16.555 -16.471 -55.756  1.00 90.28  ? 27  ASP C CB  1 
ATOM   4092  C CG  . ASP C 1 21  ? -16.686 -17.815 -55.070  1.00 95.52  ? 27  ASP C CG  1 
ATOM   4093  O OD1 . ASP C 1 21  ? -15.862 -18.710 -55.354  1.00 98.52  ? 27  ASP C OD1 1 
ATOM   4094  O OD2 . ASP C 1 21  ? -17.620 -17.981 -54.257  1.00 99.07  ? 27  ASP C OD2 1 
ATOM   4095  N N   . THR C 1 22  ? -17.108 -15.487 -58.717  1.00 77.21  ? 28  THR C N   1 
ATOM   4096  C CA  . THR C 1 22  ? -17.586 -14.415 -59.573  1.00 79.21  ? 28  THR C CA  1 
ATOM   4097  C C   . THR C 1 22  ? -19.105 -14.404 -59.502  1.00 77.07  ? 28  THR C C   1 
ATOM   4098  O O   . THR C 1 22  ? -19.726 -15.351 -59.014  1.00 85.48  ? 28  THR C O   1 
ATOM   4099  C CB  . THR C 1 22  ? -17.087 -14.578 -61.017  1.00 91.42  ? 28  THR C CB  1 
ATOM   4100  O OG1 . THR C 1 22  ? -17.298 -13.358 -61.738  1.00 96.91  ? 28  THR C OG1 1 
ATOM   4101  C CG2 . THR C 1 22  ? -17.818 -15.700 -61.720  1.00 77.63  ? 28  THR C CG2 1 
ATOM   4102  N N   . ILE C 1 23  ? -19.706 -13.309 -59.975  1.00 75.25  ? 29  ILE C N   1 
ATOM   4103  C CA  . ILE C 1 23  ? -21.118 -13.069 -59.694  1.00 84.92  ? 29  ILE C CA  1 
ATOM   4104  C C   . ILE C 1 23  ? -22.043 -14.087 -60.354  1.00 86.01  ? 29  ILE C C   1 
ATOM   4105  O O   . ILE C 1 23  ? -23.212 -14.179 -59.969  1.00 85.91  ? 29  ILE C O   1 
ATOM   4106  C CB  . ILE C 1 23  ? -21.490 -11.615 -60.071  1.00 78.18  ? 29  ILE C CB  1 
ATOM   4107  C CG1 . ILE C 1 23  ? -22.830 -11.204 -59.454  1.00 84.20  ? 29  ILE C CG1 1 
ATOM   4108  C CG2 . ILE C 1 23  ? -21.537 -11.421 -61.567  1.00 88.00  ? 29  ILE C CG2 1 
ATOM   4109  C CD1 . ILE C 1 23  ? -23.200 -9.758  -59.722  1.00 74.31  ? 29  ILE C CD1 1 
ATOM   4110  N N   . MET C 1 24  ? -21.554 -14.888 -61.308  1.00 84.94  ? 30  MET C N   1 
ATOM   4111  C CA  . MET C 1 24  ? -22.355 -15.973 -61.866  1.00 84.99  ? 30  MET C CA  1 
ATOM   4112  C C   . MET C 1 24  ? -21.784 -17.366 -61.650  1.00 91.08  ? 30  MET C C   1 
ATOM   4113  O O   . MET C 1 24  ? -22.541 -18.337 -61.747  1.00 97.12  ? 30  MET C O   1 
ATOM   4114  C CB  . MET C 1 24  ? -22.575 -15.777 -63.373  1.00 85.73  ? 30  MET C CB  1 
ATOM   4115  C CG  . MET C 1 24  ? -23.674 -14.791 -63.684  1.00 92.69  ? 30  MET C CG  1 
ATOM   4116  S SD  . MET C 1 24  ? -23.819 -14.385 -65.427  1.00 102.10 ? 30  MET C SD  1 
ATOM   4117  C CE  . MET C 1 24  ? -24.567 -12.767 -65.282  1.00 83.32  ? 30  MET C CE  1 
ATOM   4118  N N   . GLU C 1 25  ? -20.491 -17.500 -61.374  1.00 89.78  ? 31  GLU C N   1 
ATOM   4119  C CA  . GLU C 1 25  ? -19.857 -18.803 -61.247  1.00 89.57  ? 31  GLU C CA  1 
ATOM   4120  C C   . GLU C 1 25  ? -19.086 -18.867 -59.939  1.00 86.87  ? 31  GLU C C   1 
ATOM   4121  O O   . GLU C 1 25  ? -18.454 -17.888 -59.532  1.00 78.76  ? 31  GLU C O   1 
ATOM   4122  C CB  . GLU C 1 25  ? -18.917 -19.080 -62.427  1.00 94.83  ? 31  GLU C CB  1 
ATOM   4123  C CG  . GLU C 1 25  ? -19.391 -18.498 -63.751  1.00 101.22 ? 31  GLU C CG  1 
ATOM   4124  C CD  . GLU C 1 25  ? -18.336 -18.580 -64.836  1.00 102.54 ? 31  GLU C CD  1 
ATOM   4125  O OE1 . GLU C 1 25  ? -17.827 -19.692 -65.089  1.00 92.44  ? 31  GLU C OE1 1 
ATOM   4126  O OE2 . GLU C 1 25  ? -18.009 -17.528 -65.428  1.00 100.63 ? 31  GLU C OE2 1 
ATOM   4127  N N   . LYS C 1 26  ? -19.138 -20.022 -59.284  1.00 84.57  ? 32  LYS C N   1 
ATOM   4128  C CA  . LYS C 1 26  ? -18.475 -20.226 -58.007  1.00 93.35  ? 32  LYS C CA  1 
ATOM   4129  C C   . LYS C 1 26  ? -17.386 -21.280 -58.148  1.00 97.44  ? 32  LYS C C   1 
ATOM   4130  O O   . LYS C 1 26  ? -17.484 -22.188 -58.979  1.00 96.51  ? 32  LYS C O   1 
ATOM   4131  C CB  . LYS C 1 26  ? -19.471 -20.653 -56.923  1.00 91.79  ? 32  LYS C CB  1 
ATOM   4132  C CG  . LYS C 1 26  ? -20.751 -19.831 -56.888  1.00 95.52  ? 32  LYS C CG  1 
ATOM   4133  C CD  . LYS C 1 26  ? -21.167 -19.556 -55.454  1.00 92.84  ? 32  LYS C CD  1 
ATOM   4134  C CE  . LYS C 1 26  ? -22.646 -19.818 -55.236  1.00 91.04  ? 32  LYS C CE  1 
ATOM   4135  N NZ  . LYS C 1 26  ? -22.989 -19.826 -53.787  1.00 86.11  ? 32  LYS C NZ  1 
ATOM   4136  N N   . ASN C 1 27  ? -16.348 -21.145 -57.322  1.00 98.81  ? 33  ASN C N   1 
ATOM   4137  C CA  . ASN C 1 27  ? -15.234 -22.094 -57.278  1.00 91.22  ? 33  ASN C CA  1 
ATOM   4138  C C   . ASN C 1 27  ? -14.605 -22.273 -58.660  1.00 91.07  ? 33  ASN C C   1 
ATOM   4139  O O   . ASN C 1 27  ? -14.455 -23.386 -59.167  1.00 101.23 ? 33  ASN C O   1 
ATOM   4140  C CB  . ASN C 1 27  ? -15.685 -23.436 -56.697  1.00 91.84  ? 33  ASN C CB  1 
ATOM   4141  C CG  . ASN C 1 27  ? -16.165 -23.318 -55.261  1.00 93.76  ? 33  ASN C CG  1 
ATOM   4142  O OD1 . ASN C 1 27  ? -16.372 -22.216 -54.753  1.00 102.30 ? 33  ASN C OD1 1 
ATOM   4143  N ND2 . ASN C 1 27  ? -16.346 -24.456 -54.602  1.00 82.74  ? 33  ASN C ND2 1 
ATOM   4144  N N   . VAL C 1 28  ? -14.235 -21.152 -59.271  1.00 87.96  ? 34  VAL C N   1 
ATOM   4145  C CA  . VAL C 1 28  ? -13.605 -21.147 -60.586  1.00 78.96  ? 34  VAL C CA  1 
ATOM   4146  C C   . VAL C 1 28  ? -12.095 -21.118 -60.408  1.00 96.71  ? 34  VAL C C   1 
ATOM   4147  O O   . VAL C 1 28  ? -11.557 -20.245 -59.716  1.00 93.19  ? 34  VAL C O   1 
ATOM   4148  C CB  . VAL C 1 28  ? -14.083 -19.947 -61.421  1.00 80.26  ? 34  VAL C CB  1 
ATOM   4149  C CG1 . VAL C 1 28  ? -13.293 -19.852 -62.717  1.00 75.59  ? 34  VAL C CG1 1 
ATOM   4150  C CG2 . VAL C 1 28  ? -15.567 -20.064 -61.706  1.00 87.85  ? 34  VAL C CG2 1 
ATOM   4151  N N   . THR C 1 29  ? -11.408 -22.068 -61.036  1.00 102.35 ? 35  THR C N   1 
ATOM   4152  C CA  . THR C 1 29  ? -9.959  -22.149 -60.932  1.00 101.98 ? 35  THR C CA  1 
ATOM   4153  C C   . THR C 1 29  ? -9.298  -21.189 -61.915  1.00 101.11 ? 35  THR C C   1 
ATOM   4154  O O   . THR C 1 29  ? -9.709  -21.081 -63.074  1.00 99.98  ? 35  THR C O   1 
ATOM   4155  C CB  . THR C 1 29  ? -9.484  -23.579 -61.192  1.00 90.64  ? 35  THR C CB  1 
ATOM   4156  O OG1 . THR C 1 29  ? -10.261 -24.489 -60.403  1.00 90.19  ? 35  THR C OG1 1 
ATOM   4157  C CG2 . THR C 1 29  ? -8.021  -23.728 -60.817  1.00 101.26 ? 35  THR C CG2 1 
ATOM   4158  N N   . VAL C 1 30  ? -8.267  -20.488 -61.440  1.00 97.83  ? 36  VAL C N   1 
ATOM   4159  C CA  . VAL C 1 30  ? -7.555  -19.492 -62.227  1.00 105.32 ? 36  VAL C CA  1 
ATOM   4160  C C   . VAL C 1 30  ? -6.061  -19.786 -62.155  1.00 107.94 ? 36  VAL C C   1 
ATOM   4161  O O   . VAL C 1 30  ? -5.609  -20.657 -61.412  1.00 105.82 ? 36  VAL C O   1 
ATOM   4162  C CB  . VAL C 1 30  ? -7.845  -18.052 -61.751  1.00 107.16 ? 36  VAL C CB  1 
ATOM   4163  C CG1 . VAL C 1 30  ? -9.318  -17.716 -61.932  1.00 93.23  ? 36  VAL C CG1 1 
ATOM   4164  C CG2 . VAL C 1 30  ? -7.427  -17.882 -60.299  1.00 98.85  ? 36  VAL C CG2 1 
ATOM   4165  N N   . THR C 1 31  ? -5.293  -19.040 -62.950  1.00 111.11 ? 37  THR C N   1 
ATOM   4166  C CA  . THR C 1 31  ? -3.841  -19.175 -62.958  1.00 113.28 ? 37  THR C CA  1 
ATOM   4167  C C   . THR C 1 31  ? -3.191  -18.333 -61.864  1.00 112.61 ? 37  THR C C   1 
ATOM   4168  O O   . THR C 1 31  ? -2.395  -18.847 -61.071  1.00 107.90 ? 37  THR C O   1 
ATOM   4169  C CB  . THR C 1 31  ? -3.278  -18.783 -64.328  1.00 111.80 ? 37  THR C CB  1 
ATOM   4170  O OG1 . THR C 1 31  ? -3.475  -17.381 -64.547  1.00 108.84 ? 37  THR C OG1 1 
ATOM   4171  C CG2 . THR C 1 31  ? -3.971  -19.565 -65.433  1.00 106.81 ? 37  THR C CG2 1 
ATOM   4172  N N   . HIS C 1 32  ? -3.519  -17.044 -61.810  1.00 116.60 ? 38  HIS C N   1 
ATOM   4173  C CA  . HIS C 1 32  ? -3.012  -16.137 -60.791  1.00 117.19 ? 38  HIS C CA  1 
ATOM   4174  C C   . HIS C 1 32  ? -4.182  -15.467 -60.083  1.00 113.09 ? 38  HIS C C   1 
ATOM   4175  O O   . HIS C 1 32  ? -5.194  -15.139 -60.711  1.00 105.33 ? 38  HIS C O   1 
ATOM   4176  C CB  . HIS C 1 32  ? -2.092  -15.068 -61.397  1.00 112.70 ? 38  HIS C CB  1 
ATOM   4177  C CG  . HIS C 1 32  ? -0.991  -15.623 -62.248  1.00 120.92 ? 38  HIS C CG  1 
ATOM   4178  N ND1 . HIS C 1 32  ? -1.203  -16.089 -63.528  1.00 116.72 ? 38  HIS C ND1 1 
ATOM   4179  C CD2 . HIS C 1 32  ? 0.332   -15.778 -62.005  1.00 117.51 ? 38  HIS C CD2 1 
ATOM   4180  C CE1 . HIS C 1 32  ? -0.059  -16.511 -64.035  1.00 123.21 ? 38  HIS C CE1 1 
ATOM   4181  N NE2 . HIS C 1 32  ? 0.888   -16.333 -63.132  1.00 122.80 ? 38  HIS C NE2 1 
ATOM   4182  N N   . ALA C 1 33  ? -4.039  -15.268 -58.774  1.00 112.49 ? 39  ALA C N   1 
ATOM   4183  C CA  . ALA C 1 33  ? -5.060  -14.595 -57.985  1.00 104.31 ? 39  ALA C CA  1 
ATOM   4184  C C   . ALA C 1 33  ? -4.387  -13.835 -56.851  1.00 102.02 ? 39  ALA C C   1 
ATOM   4185  O O   . ALA C 1 33  ? -3.309  -14.213 -56.385  1.00 95.59  ? 39  ALA C O   1 
ATOM   4186  C CB  . ALA C 1 33  ? -6.092  -15.581 -57.428  1.00 98.73  ? 39  ALA C CB  1 
ATOM   4187  N N   . GLN C 1 34  ? -5.041  -12.764 -56.406  1.00 99.59  ? 40  GLN C N   1 
ATOM   4188  C CA  . GLN C 1 34  ? -4.490  -11.871 -55.393  1.00 96.17  ? 40  GLN C CA  1 
ATOM   4189  C C   . GLN C 1 34  ? -5.553  -11.604 -54.339  1.00 98.79  ? 40  GLN C C   1 
ATOM   4190  O O   . GLN C 1 34  ? -6.647  -11.130 -54.664  1.00 99.33  ? 40  GLN C O   1 
ATOM   4191  C CB  . GLN C 1 34  ? -4.010  -10.563 -56.029  1.00 93.64  ? 40  GLN C CB  1 
ATOM   4192  C CG  . GLN C 1 34  ? -3.006  -9.782  -55.200  1.00 80.54  ? 40  GLN C CG  1 
ATOM   4193  C CD  . GLN C 1 34  ? -2.207  -8.804  -56.041  1.00 100.07 ? 40  GLN C CD  1 
ATOM   4194  O OE1 . GLN C 1 34  ? -2.241  -8.856  -57.271  1.00 98.60  ? 40  GLN C OE1 1 
ATOM   4195  N NE2 . GLN C 1 34  ? -1.481  -7.908  -55.382  1.00 102.39 ? 40  GLN C NE2 1 
ATOM   4196  N N   . ASP C 1 35  ? -5.232  -11.905 -53.083  1.00 84.03  ? 41  ASP C N   1 
ATOM   4197  C CA  . ASP C 1 35  ? -6.145  -11.683 -51.969  1.00 77.08  ? 41  ASP C CA  1 
ATOM   4198  C C   . ASP C 1 35  ? -5.893  -10.301 -51.380  1.00 86.34  ? 41  ASP C C   1 
ATOM   4199  O O   . ASP C 1 35  ? -4.757  -9.969  -51.027  1.00 90.85  ? 41  ASP C O   1 
ATOM   4200  C CB  . ASP C 1 35  ? -5.963  -12.763 -50.900  1.00 74.17  ? 41  ASP C CB  1 
ATOM   4201  C CG  . ASP C 1 35  ? -7.139  -12.846 -49.938  1.00 87.41  ? 41  ASP C CG  1 
ATOM   4202  O OD1 . ASP C 1 35  ? -7.866  -11.841 -49.781  1.00 81.99  ? 41  ASP C OD1 1 
ATOM   4203  O OD2 . ASP C 1 35  ? -7.336  -13.921 -49.334  1.00 83.97  ? 41  ASP C OD2 1 
ATOM   4204  N N   . ILE C 1 36  ? -6.953  -9.500  -51.275  1.00 86.69  ? 42  ILE C N   1 
ATOM   4205  C CA  . ILE C 1 36  ? -6.851  -8.128  -50.793  1.00 85.51  ? 42  ILE C CA  1 
ATOM   4206  C C   . ILE C 1 36  ? -7.389  -7.981  -49.375  1.00 81.51  ? 42  ILE C C   1 
ATOM   4207  O O   . ILE C 1 36  ? -7.566  -6.855  -48.897  1.00 74.52  ? 42  ILE C O   1 
ATOM   4208  C CB  . ILE C 1 36  ? -7.547  -7.145  -51.748  1.00 67.27  ? 42  ILE C CB  1 
ATOM   4209  C CG1 . ILE C 1 36  ? -9.045  -7.442  -51.829  1.00 70.27  ? 42  ILE C CG1 1 
ATOM   4210  C CG2 . ILE C 1 36  ? -6.912  -7.203  -53.129  1.00 76.78  ? 42  ILE C CG2 1 
ATOM   4211  C CD1 . ILE C 1 36  ? -9.805  -6.480  -52.715  1.00 69.63  ? 42  ILE C CD1 1 
ATOM   4212  N N   . LEU C 1 37  ? -7.655  -9.086  -48.687  1.00 74.37  ? 43  LEU C N   1 
ATOM   4213  C CA  . LEU C 1 37  ? -8.096  -9.056  -47.299  1.00 70.42  ? 43  LEU C CA  1 
ATOM   4214  C C   . LEU C 1 37  ? -6.894  -9.239  -46.383  1.00 77.70  ? 43  LEU C C   1 
ATOM   4215  O O   . LEU C 1 37  ? -6.148  -10.214 -46.517  1.00 75.23  ? 43  LEU C O   1 
ATOM   4216  C CB  . LEU C 1 37  ? -9.136  -10.142 -47.023  1.00 71.37  ? 43  LEU C CB  1 
ATOM   4217  C CG  . LEU C 1 37  ? -9.670  -10.145 -45.590  1.00 70.55  ? 43  LEU C CG  1 
ATOM   4218  C CD1 . LEU C 1 37  ? -10.388 -8.838  -45.298  1.00 55.80  ? 43  LEU C CD1 1 
ATOM   4219  C CD2 . LEU C 1 37  ? -10.588 -11.328 -45.350  1.00 73.51  ? 43  LEU C CD2 1 
ATOM   4220  N N   . GLU C 1 38  ? -6.714  -8.303  -45.455  1.00 82.32  ? 44  GLU C N   1 
ATOM   4221  C CA  . GLU C 1 38  ? -5.598  -8.364  -44.522  1.00 64.86  ? 44  GLU C CA  1 
ATOM   4222  C C   . GLU C 1 38  ? -5.965  -9.243  -43.333  1.00 65.96  ? 44  GLU C C   1 
ATOM   4223  O O   . GLU C 1 38  ? -6.988  -9.020  -42.678  1.00 70.28  ? 44  GLU C O   1 
ATOM   4224  C CB  . GLU C 1 38  ? -5.220  -6.958  -44.057  1.00 70.71  ? 44  GLU C CB  1 
ATOM   4225  C CG  . GLU C 1 38  ? -4.046  -6.923  -43.105  1.00 76.87  ? 44  GLU C CG  1 
ATOM   4226  C CD  . GLU C 1 38  ? -2.816  -7.589  -43.682  1.00 83.85  ? 44  GLU C CD  1 
ATOM   4227  O OE1 . GLU C 1 38  ? -2.526  -7.385  -44.880  1.00 89.20  ? 44  GLU C OE1 1 
ATOM   4228  O OE2 . GLU C 1 38  ? -2.142  -8.325  -42.937  1.00 85.50  ? 44  GLU C OE2 1 
ATOM   4229  N N   . LYS C 1 39  ? -5.129  -10.247 -43.055  1.00 74.69  ? 45  LYS C N   1 
ATOM   4230  C CA  . LYS C 1 39  ? -5.447  -11.244 -42.041  1.00 70.12  ? 45  LYS C CA  1 
ATOM   4231  C C   . LYS C 1 39  ? -4.359  -11.477 -41.002  1.00 60.09  ? 45  LYS C C   1 
ATOM   4232  O O   . LYS C 1 39  ? -4.621  -12.189 -40.026  1.00 68.32  ? 45  LYS C O   1 
ATOM   4233  C CB  . LYS C 1 39  ? -5.772  -12.597 -42.697  1.00 76.91  ? 45  LYS C CB  1 
ATOM   4234  C CG  . LYS C 1 39  ? -6.743  -12.528 -43.861  1.00 84.17  ? 45  LYS C CG  1 
ATOM   4235  C CD  . LYS C 1 39  ? -7.012  -13.916 -44.420  1.00 76.04  ? 45  LYS C CD  1 
ATOM   4236  C CE  . LYS C 1 39  ? -7.314  -13.862 -45.907  1.00 83.16  ? 45  LYS C CE  1 
ATOM   4237  N NZ  . LYS C 1 39  ? -6.156  -13.339 -46.683  1.00 78.94  ? 45  LYS C NZ  1 
ATOM   4238  N N   . THR C 1 40  ? -3.162  -10.924 -41.168  1.00 63.85  ? 46  THR C N   1 
ATOM   4239  C CA  . THR C 1 40  ? -2.045  -11.225 -40.284  1.00 72.50  ? 46  THR C CA  1 
ATOM   4240  C C   . THR C 1 40  ? -1.648  -10.001 -39.468  1.00 80.32  ? 46  THR C C   1 
ATOM   4241  O O   . THR C 1 40  ? -1.686  -8.869  -39.960  1.00 66.03  ? 46  THR C O   1 
ATOM   4242  C CB  . THR C 1 40  ? -0.831  -11.740 -41.070  1.00 82.77  ? 46  THR C CB  1 
ATOM   4243  O OG1 . THR C 1 40  ? 0.330   -11.716 -40.231  1.00 87.97  ? 46  THR C OG1 1 
ATOM   4244  C CG2 . THR C 1 40  ? -0.576  -10.893 -42.303  1.00 69.35  ? 46  THR C CG2 1 
ATOM   4245  N N   . HIS C 1 41  ? -1.272  -10.245 -38.214  1.00 74.30  ? 47  HIS C N   1 
ATOM   4246  C CA  . HIS C 1 41  ? -0.782  -9.214  -37.313  1.00 68.42  ? 47  HIS C CA  1 
ATOM   4247  C C   . HIS C 1 41  ? 0.417   -9.765  -36.556  1.00 71.94  ? 47  HIS C C   1 
ATOM   4248  O O   . HIS C 1 41  ? 0.593   -10.980 -36.439  1.00 72.13  ? 47  HIS C O   1 
ATOM   4249  C CB  . HIS C 1 41  ? -1.876  -8.747  -36.341  1.00 69.12  ? 47  HIS C CB  1 
ATOM   4250  C CG  . HIS C 1 41  ? -2.437  -9.842  -35.489  1.00 57.55  ? 47  HIS C CG  1 
ATOM   4251  N ND1 . HIS C 1 41  ? -1.780  -10.336 -34.382  1.00 70.19  ? 47  HIS C ND1 1 
ATOM   4252  C CD2 . HIS C 1 41  ? -3.595  -10.539 -35.580  1.00 59.65  ? 47  HIS C CD2 1 
ATOM   4253  C CE1 . HIS C 1 41  ? -2.507  -11.290 -33.829  1.00 63.31  ? 47  HIS C CE1 1 
ATOM   4254  N NE2 . HIS C 1 41  ? -3.614  -11.432 -34.536  1.00 67.38  ? 47  HIS C NE2 1 
ATOM   4255  N N   . ASN C 1 42  ? 1.246   -8.860  -36.033  1.00 67.66  ? 48  ASN C N   1 
ATOM   4256  C CA  . ASN C 1 42  ? 2.489   -9.276  -35.392  1.00 55.74  ? 48  ASN C CA  1 
ATOM   4257  C C   . ASN C 1 42  ? 2.300   -9.745  -33.953  1.00 64.76  ? 48  ASN C C   1 
ATOM   4258  O O   . ASN C 1 42  ? 3.283   -10.144 -33.319  1.00 84.01  ? 48  ASN C O   1 
ATOM   4259  C CB  . ASN C 1 42  ? 3.527   -8.147  -35.446  1.00 63.14  ? 48  ASN C CB  1 
ATOM   4260  C CG  . ASN C 1 42  ? 3.118   -6.915  -34.650  1.00 76.87  ? 48  ASN C CG  1 
ATOM   4261  O OD1 . ASN C 1 42  ? 2.101   -6.905  -33.956  1.00 72.71  ? 48  ASN C OD1 1 
ATOM   4262  N ND2 . ASN C 1 42  ? 3.926   -5.864  -34.746  1.00 64.16  ? 48  ASN C ND2 1 
ATOM   4263  N N   . GLY C 1 43  ? 1.080   -9.695  -33.421  1.00 64.89  ? 49  GLY C N   1 
ATOM   4264  C CA  . GLY C 1 43  ? 0.806   -10.252 -32.111  1.00 60.78  ? 49  GLY C CA  1 
ATOM   4265  C C   . GLY C 1 43  ? 1.419   -9.511  -30.945  1.00 77.97  ? 49  GLY C C   1 
ATOM   4266  O O   . GLY C 1 43  ? 1.543   -10.083 -29.859  1.00 66.40  ? 49  GLY C O   1 
ATOM   4267  N N   . LYS C 1 44  ? 1.802   -8.250  -31.130  1.00 67.10  ? 50  LYS C N   1 
ATOM   4268  C CA  . LYS C 1 44  ? 2.439   -7.477  -30.075  1.00 71.41  ? 50  LYS C CA  1 
ATOM   4269  C C   . LYS C 1 44  ? 1.912   -6.049  -30.101  1.00 64.23  ? 50  LYS C C   1 
ATOM   4270  O O   . LYS C 1 44  ? 1.411   -5.567  -31.119  1.00 54.40  ? 50  LYS C O   1 
ATOM   4271  C CB  . LYS C 1 44  ? 3.970   -7.486  -30.218  1.00 71.98  ? 50  LYS C CB  1 
ATOM   4272  C CG  . LYS C 1 44  ? 4.633   -8.798  -29.805  1.00 84.26  ? 50  LYS C CG  1 
ATOM   4273  C CD  . LYS C 1 44  ? 6.129   -8.787  -30.092  1.00 88.54  ? 50  LYS C CD  1 
ATOM   4274  C CE  . LYS C 1 44  ? 6.417   -9.096  -31.554  1.00 93.56  ? 50  LYS C CE  1 
ATOM   4275  N NZ  . LYS C 1 44  ? 7.768   -8.625  -31.978  1.00 83.94  ? 50  LYS C NZ  1 
ATOM   4276  N N   . LEU C 1 45  ? 2.019   -5.376  -28.956  1.00 71.04  ? 51  LEU C N   1 
ATOM   4277  C CA  . LEU C 1 45  ? 1.707   -3.954  -28.881  1.00 58.42  ? 51  LEU C CA  1 
ATOM   4278  C C   . LEU C 1 45  ? 2.928   -3.144  -29.297  1.00 58.94  ? 51  LEU C C   1 
ATOM   4279  O O   . LEU C 1 45  ? 4.038   -3.381  -28.810  1.00 65.92  ? 51  LEU C O   1 
ATOM   4280  C CB  . LEU C 1 45  ? 1.266   -3.568  -27.471  1.00 55.55  ? 51  LEU C CB  1 
ATOM   4281  C CG  . LEU C 1 45  ? 0.022   -4.274  -26.927  1.00 56.33  ? 51  LEU C CG  1 
ATOM   4282  C CD1 . LEU C 1 45  ? -0.471  -3.593  -25.660  1.00 61.14  ? 51  LEU C CD1 1 
ATOM   4283  C CD2 . LEU C 1 45  ? -1.077  -4.329  -27.977  1.00 55.68  ? 51  LEU C CD2 1 
ATOM   4284  N N   . CYS C 1 46  ? 2.725   -2.189  -30.198  1.00 45.47  ? 52  CYS C N   1 
ATOM   4285  C CA  . CYS C 1 46  ? 3.823   -1.455  -30.806  1.00 60.90  ? 52  CYS C CA  1 
ATOM   4286  C C   . CYS C 1 46  ? 3.692   0.035   -30.528  1.00 76.13  ? 52  CYS C C   1 
ATOM   4287  O O   . CYS C 1 46  ? 2.677   0.518   -30.017  1.00 68.28  ? 52  CYS C O   1 
ATOM   4288  C CB  . CYS C 1 46  ? 3.878   -1.689  -32.324  1.00 55.97  ? 52  CYS C CB  1 
ATOM   4289  S SG  . CYS C 1 46  ? 4.141   -3.401  -32.848  1.00 81.76  ? 52  CYS C SG  1 
ATOM   4290  N N   . ASP C 1 47  ? 4.754   0.759   -30.865  1.00 75.86  ? 53  ASP C N   1 
ATOM   4291  C CA  . ASP C 1 47  ? 4.676   2.207   -30.944  1.00 63.08  ? 53  ASP C CA  1 
ATOM   4292  C C   . ASP C 1 47  ? 3.762   2.606   -32.093  1.00 64.65  ? 53  ASP C C   1 
ATOM   4293  O O   . ASP C 1 47  ? 3.667   1.915   -33.110  1.00 69.04  ? 53  ASP C O   1 
ATOM   4294  C CB  . ASP C 1 47  ? 6.064   2.813   -31.152  1.00 69.42  ? 53  ASP C CB  1 
ATOM   4295  C CG  . ASP C 1 47  ? 6.992   2.568   -29.979  1.00 65.81  ? 53  ASP C CG  1 
ATOM   4296  O OD1 . ASP C 1 47  ? 6.598   1.833   -29.052  1.00 72.49  ? 53  ASP C OD1 1 
ATOM   4297  O OD2 . ASP C 1 47  ? 8.115   3.114   -29.984  1.00 76.90  ? 53  ASP C OD2 1 
ATOM   4298  N N   . LEU C 1 48  ? 3.075   3.728   -31.919  1.00 67.90  ? 54  LEU C N   1 
ATOM   4299  C CA  . LEU C 1 48  ? 2.178   4.262   -32.936  1.00 59.01  ? 54  LEU C CA  1 
ATOM   4300  C C   . LEU C 1 48  ? 2.822   5.511   -33.521  1.00 62.04  ? 54  LEU C C   1 
ATOM   4301  O O   . LEU C 1 48  ? 2.866   6.558   -32.865  1.00 62.53  ? 54  LEU C O   1 
ATOM   4302  C CB  . LEU C 1 48  ? 0.803   4.565   -32.347  1.00 58.46  ? 54  LEU C CB  1 
ATOM   4303  C CG  . LEU C 1 48  ? -0.271  4.994   -33.344  1.00 63.33  ? 54  LEU C CG  1 
ATOM   4304  C CD1 . LEU C 1 48  ? -0.299  4.051   -34.537  1.00 63.01  ? 54  LEU C CD1 1 
ATOM   4305  C CD2 . LEU C 1 48  ? -1.624  5.030   -32.662  1.00 69.54  ? 54  LEU C CD2 1 
ATOM   4306  N N   . ASN C 1 49  ? 3.315   5.397   -34.754  1.00 75.68  ? 55  ASN C N   1 
ATOM   4307  C CA  . ASN C 1 49  ? 4.011   6.489   -35.431  1.00 68.17  ? 55  ASN C CA  1 
ATOM   4308  C C   . ASN C 1 49  ? 5.152   7.022   -34.567  1.00 72.94  ? 55  ASN C C   1 
ATOM   4309  O O   . ASN C 1 49  ? 5.240   8.213   -34.263  1.00 78.04  ? 55  ASN C O   1 
ATOM   4310  C CB  . ASN C 1 49  ? 3.037   7.603   -35.819  1.00 70.93  ? 55  ASN C CB  1 
ATOM   4311  C CG  . ASN C 1 49  ? 2.034   7.161   -36.873  1.00 74.08  ? 55  ASN C CG  1 
ATOM   4312  O OD1 . ASN C 1 49  ? 2.407   6.626   -37.917  1.00 67.14  ? 55  ASN C OD1 1 
ATOM   4313  N ND2 . ASN C 1 49  ? 0.753   7.376   -36.598  1.00 68.01  ? 55  ASN C ND2 1 
ATOM   4314  N N   . GLY C 1 50  A 6.013   6.106   -34.130  1.00 67.79  ? 55  GLY C N   1 
ATOM   4315  C CA  . GLY C 1 50  A 7.227   6.459   -33.427  1.00 63.90  ? 55  GLY C CA  1 
ATOM   4316  C C   . GLY C 1 50  A 7.063   6.825   -31.969  1.00 70.21  ? 55  GLY C C   1 
ATOM   4317  O O   . GLY C 1 50  A 8.065   7.142   -31.316  1.00 66.00  ? 55  GLY C O   1 
ATOM   4318  N N   . VAL C 1 51  ? 5.847   6.788   -31.430  1.00 74.09  ? 56  VAL C N   1 
ATOM   4319  C CA  . VAL C 1 51  ? 5.585   7.181   -30.049  1.00 62.78  ? 56  VAL C CA  1 
ATOM   4320  C C   . VAL C 1 51  ? 5.097   5.958   -29.287  1.00 55.02  ? 56  VAL C C   1 
ATOM   4321  O O   . VAL C 1 51  ? 4.118   5.316   -29.689  1.00 63.41  ? 56  VAL C O   1 
ATOM   4322  C CB  . VAL C 1 51  ? 4.569   8.330   -29.961  1.00 65.42  ? 56  VAL C CB  1 
ATOM   4323  C CG1 . VAL C 1 51  ? 4.267   8.651   -28.509  1.00 59.17  ? 56  VAL C CG1 1 
ATOM   4324  C CG2 . VAL C 1 51  ? 5.102   9.563   -30.672  1.00 68.31  ? 56  VAL C CG2 1 
ATOM   4325  N N   . LYS C 1 52  ? 5.779   5.642   -28.190  1.00 57.46  ? 57  LYS C N   1 
ATOM   4326  C CA  . LYS C 1 52  ? 5.439   4.489   -27.375  1.00 62.65  ? 57  LYS C CA  1 
ATOM   4327  C C   . LYS C 1 52  ? 4.148   4.744   -26.593  1.00 57.87  ? 57  LYS C C   1 
ATOM   4328  O O   . LYS C 1 52  ? 3.862   5.879   -26.204  1.00 66.18  ? 57  LYS C O   1 
ATOM   4329  C CB  . LYS C 1 52  ? 6.594   4.182   -26.420  1.00 63.54  ? 57  LYS C CB  1 
ATOM   4330  C CG  . LYS C 1 52  ? 6.230   3.459   -25.134  1.00 77.14  ? 57  LYS C CG  1 
ATOM   4331  C CD  . LYS C 1 52  ? 7.465   3.200   -24.282  1.00 79.11  ? 57  LYS C CD  1 
ATOM   4332  C CE  . LYS C 1 52  ? 7.138   2.371   -23.046  1.00 81.45  ? 57  LYS C CE  1 
ATOM   4333  N NZ  . LYS C 1 52  ? 7.108   0.908   -23.329  1.00 77.74  ? 57  LYS C NZ  1 
ATOM   4334  N N   . PRO C 1 53  ? 3.340   3.710   -26.370  1.00 63.02  ? 58  PRO C N   1 
ATOM   4335  C CA  . PRO C 1 53  ? 2.143   3.870   -25.540  1.00 46.48  ? 58  PRO C CA  1 
ATOM   4336  C C   . PRO C 1 53  ? 2.472   3.917   -24.055  1.00 56.99  ? 58  PRO C C   1 
ATOM   4337  O O   . PRO C 1 53  ? 3.544   3.512   -23.607  1.00 54.58  ? 58  PRO C O   1 
ATOM   4338  C CB  . PRO C 1 53  ? 1.316   2.623   -25.870  1.00 48.72  ? 58  PRO C CB  1 
ATOM   4339  C CG  . PRO C 1 53  ? 2.330   1.609   -26.264  1.00 63.28  ? 58  PRO C CG  1 
ATOM   4340  C CD  . PRO C 1 53  ? 3.408   2.372   -26.984  1.00 53.27  ? 58  PRO C CD  1 
ATOM   4341  N N   . LEU C 1 54  ? 1.509   4.424   -23.289  1.00 50.43  ? 59  LEU C N   1 
ATOM   4342  C CA  . LEU C 1 54  ? 1.567   4.377   -21.833  1.00 48.94  ? 59  LEU C CA  1 
ATOM   4343  C C   . LEU C 1 54  ? 0.898   3.094   -21.360  1.00 56.06  ? 59  LEU C C   1 
ATOM   4344  O O   . LEU C 1 54  ? -0.311  2.913   -21.546  1.00 53.72  ? 59  LEU C O   1 
ATOM   4345  C CB  . LEU C 1 54  ? 0.882   5.592   -21.213  1.00 57.50  ? 59  LEU C CB  1 
ATOM   4346  C CG  . LEU C 1 54  ? 0.723   5.550   -19.692  1.00 57.20  ? 59  LEU C CG  1 
ATOM   4347  C CD1 . LEU C 1 54  ? 2.085   5.566   -19.010  1.00 58.89  ? 59  LEU C CD1 1 
ATOM   4348  C CD2 . LEU C 1 54  ? -0.143  6.702   -19.207  1.00 55.13  ? 59  LEU C CD2 1 
ATOM   4349  N N   . ILE C 1 55  ? 1.679   2.204   -20.761  1.00 59.42  ? 60  ILE C N   1 
ATOM   4350  C CA  . ILE C 1 55  ? 1.209   0.877   -20.393  1.00 60.94  ? 60  ILE C CA  1 
ATOM   4351  C C   . ILE C 1 55  ? 1.085   0.839   -18.875  1.00 68.76  ? 60  ILE C C   1 
ATOM   4352  O O   . ILE C 1 55  ? 2.074   0.659   -18.156  1.00 73.64  ? 60  ILE C O   1 
ATOM   4353  C CB  . ILE C 1 55  ? 2.136   -0.225  -20.915  1.00 55.33  ? 60  ILE C CB  1 
ATOM   4354  C CG1 . ILE C 1 55  ? 2.406   -0.012  -22.405  1.00 63.50  ? 60  ILE C CG1 1 
ATOM   4355  C CG2 . ILE C 1 55  ? 1.516   -1.592  -20.680  1.00 72.00  ? 60  ILE C CG2 1 
ATOM   4356  C CD1 . ILE C 1 55  ? 3.083   -1.181  -23.081  1.00 65.00  ? 60  ILE C CD1 1 
ATOM   4357  N N   . LEU C 1 56  ? -0.138  1.014   -18.384  1.00 63.62  ? 61  LEU C N   1 
ATOM   4358  C CA  . LEU C 1 56  ? -0.440  0.792   -16.978  1.00 66.23  ? 61  LEU C CA  1 
ATOM   4359  C C   . LEU C 1 56  ? -0.649  -0.703  -16.769  1.00 80.95  ? 61  LEU C C   1 
ATOM   4360  O O   . LEU C 1 56  ? -1.549  -1.298  -17.374  1.00 93.39  ? 61  LEU C O   1 
ATOM   4361  C CB  . LEU C 1 56  ? -1.676  1.591   -16.572  1.00 53.21  ? 61  LEU C CB  1 
ATOM   4362  C CG  . LEU C 1 56  ? -1.722  3.036   -17.083  1.00 69.25  ? 61  LEU C CG  1 
ATOM   4363  C CD1 . LEU C 1 56  ? -3.073  3.682   -16.800  1.00 48.81  ? 61  LEU C CD1 1 
ATOM   4364  C CD2 . LEU C 1 56  ? -0.594  3.866   -16.485  1.00 61.23  ? 61  LEU C CD2 1 
ATOM   4365  N N   . LYS C 1 57  ? 0.185   -1.316  -15.929  1.00 81.66  ? 62  LYS C N   1 
ATOM   4366  C CA  . LYS C 1 57  ? 0.215   -2.773  -15.854  1.00 71.32  ? 62  LYS C CA  1 
ATOM   4367  C C   . LYS C 1 57  ? -1.037  -3.313  -15.169  1.00 81.83  ? 62  LYS C C   1 
ATOM   4368  O O   . LYS C 1 57  ? -1.854  -4.003  -15.788  1.00 98.59  ? 62  LYS C O   1 
ATOM   4369  C CB  . LYS C 1 57  ? 1.478   -3.225  -15.117  1.00 84.97  ? 62  LYS C CB  1 
ATOM   4370  C CG  . LYS C 1 57  ? 2.743   -2.551  -15.609  1.00 90.02  ? 62  LYS C CG  1 
ATOM   4371  C CD  . LYS C 1 57  ? 3.829   -2.568  -14.545  1.00 100.07 ? 62  LYS C CD  1 
ATOM   4372  C CE  . LYS C 1 57  ? 5.024   -1.726  -14.964  1.00 97.55  ? 62  LYS C CE  1 
ATOM   4373  N NZ  . LYS C 1 57  ? 6.028   -1.604  -13.872  1.00 101.21 ? 62  LYS C NZ  1 
ATOM   4374  N N   . ASP C 1 58  ? -1.210  -2.994  -13.886  1.00 73.52  ? 63  ASP C N   1 
ATOM   4375  C CA  . ASP C 1 58  ? -2.405  -3.376  -13.140  1.00 83.31  ? 63  ASP C CA  1 
ATOM   4376  C C   . ASP C 1 58  ? -2.991  -2.184  -12.394  1.00 73.74  ? 63  ASP C C   1 
ATOM   4377  O O   . ASP C 1 58  ? -3.793  -2.363  -11.471  1.00 75.96  ? 63  ASP C O   1 
ATOM   4378  C CB  . ASP C 1 58  ? -2.101  -4.521  -12.170  1.00 83.55  ? 63  ASP C CB  1 
ATOM   4379  C CG  . ASP C 1 58  ? -2.551  -5.867  -12.704  1.00 97.43  ? 63  ASP C CG  1 
ATOM   4380  O OD1 . ASP C 1 58  ? -3.750  -6.005  -13.029  1.00 84.13  ? 63  ASP C OD1 1 
ATOM   4381  O OD2 . ASP C 1 58  ? -1.704  -6.780  -12.810  1.00 105.26 ? 63  ASP C OD2 1 
ATOM   4382  N N   . CYS C 1 59  ? -2.598  -0.977  -12.779  1.00 68.72  ? 64  CYS C N   1 
ATOM   4383  C CA  . CYS C 1 59  ? -3.107  0.253   -12.198  1.00 64.92  ? 64  CYS C CA  1 
ATOM   4384  C C   . CYS C 1 59  ? -4.101  0.884   -13.163  1.00 67.90  ? 64  CYS C C   1 
ATOM   4385  O O   . CYS C 1 59  ? -3.906  0.849   -14.381  1.00 64.77  ? 64  CYS C O   1 
ATOM   4386  C CB  . CYS C 1 59  ? -1.958  1.223   -11.909  1.00 63.00  ? 64  CYS C CB  1 
ATOM   4387  S SG  . CYS C 1 59  ? -2.261  2.431   -10.596  1.00 101.50 ? 64  CYS C SG  1 
ATOM   4388  N N   . SER C 1 60  ? -5.181  1.434   -12.619  1.00 58.06  ? 65  SER C N   1 
ATOM   4389  C CA  . SER C 1 60  ? -6.091  2.200   -13.451  1.00 52.33  ? 65  SER C CA  1 
ATOM   4390  C C   . SER C 1 60  ? -5.519  3.593   -13.697  1.00 58.75  ? 65  SER C C   1 
ATOM   4391  O O   . SER C 1 60  ? -4.518  4.001   -13.101  1.00 52.12  ? 65  SER C O   1 
ATOM   4392  C CB  . SER C 1 60  ? -7.470  2.297   -12.802  1.00 51.96  ? 65  SER C CB  1 
ATOM   4393  O OG  . SER C 1 60  ? -7.446  3.178   -11.692  1.00 59.38  ? 65  SER C OG  1 
ATOM   4394  N N   . VAL C 1 61  ? -6.165  4.331   -14.601  1.00 49.38  ? 66  VAL C N   1 
ATOM   4395  C CA  . VAL C 1 61  ? -5.776  5.720   -14.821  1.00 51.25  ? 66  VAL C CA  1 
ATOM   4396  C C   . VAL C 1 61  ? -5.927  6.518   -13.533  1.00 45.82  ? 66  VAL C C   1 
ATOM   4397  O O   . VAL C 1 61  ? -5.051  7.312   -13.169  1.00 48.72  ? 66  VAL C O   1 
ATOM   4398  C CB  . VAL C 1 61  ? -6.598  6.332   -15.970  1.00 52.67  ? 66  VAL C CB  1 
ATOM   4399  C CG1 . VAL C 1 61  ? -6.361  7.832   -16.053  1.00 42.82  ? 66  VAL C CG1 1 
ATOM   4400  C CG2 . VAL C 1 61  ? -6.245  5.659   -17.287  1.00 41.63  ? 66  VAL C CG2 1 
ATOM   4401  N N   . ALA C 1 62  ? -7.033  6.305   -12.814  1.00 48.35  ? 67  ALA C N   1 
ATOM   4402  C CA  . ALA C 1 62  ? -7.268  7.038   -11.573  1.00 44.32  ? 67  ALA C CA  1 
ATOM   4403  C C   . ALA C 1 62  ? -6.218  6.707   -10.519  1.00 44.66  ? 67  ALA C C   1 
ATOM   4404  O O   . ALA C 1 62  ? -5.698  7.607   -9.848   1.00 51.04  ? 67  ALA C O   1 
ATOM   4405  C CB  . ALA C 1 62  ? -8.671  6.736   -11.046  1.00 40.28  ? 67  ALA C CB  1 
ATOM   4406  N N   . GLY C 1 63  ? -5.893  5.423   -10.354  1.00 41.72  ? 68  GLY C N   1 
ATOM   4407  C CA  . GLY C 1 63  ? -4.870  5.048   -9.389   1.00 41.95  ? 68  GLY C CA  1 
ATOM   4408  C C   . GLY C 1 63  ? -3.496  5.574   -9.749   1.00 45.40  ? 68  GLY C C   1 
ATOM   4409  O O   . GLY C 1 63  ? -2.694  5.892   -8.868   1.00 45.57  ? 68  GLY C O   1 
ATOM   4410  N N   . TRP C 1 64  ? -3.201  5.663   -11.045  1.00 44.16  ? 69  TRP C N   1 
ATOM   4411  C CA  . TRP C 1 64  ? -1.920  6.200   -11.491  1.00 51.06  ? 69  TRP C CA  1 
ATOM   4412  C C   . TRP C 1 64  ? -1.819  7.697   -11.209  1.00 54.69  ? 69  TRP C C   1 
ATOM   4413  O O   . TRP C 1 64  ? -0.812  8.169   -10.670  1.00 51.16  ? 69  TRP C O   1 
ATOM   4414  C CB  . TRP C 1 64  ? -1.743  5.895   -12.980  1.00 42.10  ? 69  TRP C CB  1 
ATOM   4415  C CG  . TRP C 1 64  ? -0.581  6.554   -13.644  1.00 59.67  ? 69  TRP C CG  1 
ATOM   4416  C CD1 . TRP C 1 64  ? 0.743   6.317   -13.412  1.00 60.08  ? 69  TRP C CD1 1 
ATOM   4417  C CD2 . TRP C 1 64  ? -0.638  7.533   -14.687  1.00 48.74  ? 69  TRP C CD2 1 
ATOM   4418  N NE1 . TRP C 1 64  ? 1.514   7.105   -14.234  1.00 60.07  ? 69  TRP C NE1 1 
ATOM   4419  C CE2 . TRP C 1 64  ? 0.690   7.860   -15.027  1.00 55.65  ? 69  TRP C CE2 1 
ATOM   4420  C CE3 . TRP C 1 64  ? -1.684  8.173   -15.361  1.00 54.01  ? 69  TRP C CE3 1 
ATOM   4421  C CZ2 . TRP C 1 64  ? 0.999   8.797   -16.009  1.00 53.09  ? 69  TRP C CZ2 1 
ATOM   4422  C CZ3 . TRP C 1 64  ? -1.375  9.103   -16.337  1.00 51.68  ? 69  TRP C CZ3 1 
ATOM   4423  C CH2 . TRP C 1 64  ? -0.045  9.405   -16.652  1.00 60.07  ? 69  TRP C CH2 1 
ATOM   4424  N N   . LEU C 1 65  ? -2.863  8.457   -11.555  1.00 48.54  ? 70  LEU C N   1 
ATOM   4425  C CA  . LEU C 1 65  ? -2.839  9.903   -11.338  1.00 47.46  ? 70  LEU C CA  1 
ATOM   4426  C C   . LEU C 1 65  ? -2.744  10.248  -9.858   1.00 49.13  ? 70  LEU C C   1 
ATOM   4427  O O   . LEU C 1 65  ? -1.990  11.148  -9.469   1.00 42.26  ? 70  LEU C O   1 
ATOM   4428  C CB  . LEU C 1 65  ? -4.086  10.549  -11.939  1.00 45.79  ? 70  LEU C CB  1 
ATOM   4429  C CG  . LEU C 1 65  ? -4.227  10.604  -13.457  1.00 51.58  ? 70  LEU C CG  1 
ATOM   4430  C CD1 . LEU C 1 65  ? -5.589  11.162  -13.806  1.00 45.65  ? 70  LEU C CD1 1 
ATOM   4431  C CD2 . LEU C 1 65  ? -3.124  11.454  -14.066  1.00 54.95  ? 70  LEU C CD2 1 
ATOM   4432  N N   . LEU C 1 66  ? -3.510  9.553   -9.018   1.00 44.27  ? 71  LEU C N   1 
ATOM   4433  C CA  . LEU C 1 66  ? -3.556  9.866   -7.597   1.00 38.35  ? 71  LEU C CA  1 
ATOM   4434  C C   . LEU C 1 66  ? -2.408  9.251   -6.809   1.00 44.93  ? 71  LEU C C   1 
ATOM   4435  O O   . LEU C 1 66  ? -2.255  9.566   -5.624   1.00 43.66  ? 71  LEU C O   1 
ATOM   4436  C CB  . LEU C 1 66  ? -4.892  9.409   -7.009   1.00 43.11  ? 71  LEU C CB  1 
ATOM   4437  C CG  . LEU C 1 66  ? -6.097  10.192  -7.526   1.00 49.60  ? 71  LEU C CG  1 
ATOM   4438  C CD1 . LEU C 1 66  ? -7.394  9.609   -6.994   1.00 45.19  ? 71  LEU C CD1 1 
ATOM   4439  C CD2 . LEU C 1 66  ? -5.959  11.658  -7.140   1.00 47.18  ? 71  LEU C CD2 1 
ATOM   4440  N N   . GLY C 1 67  ? -1.596  8.401   -7.431   1.00 44.31  ? 72  GLY C N   1 
ATOM   4441  C CA  . GLY C 1 67  ? -0.487  7.780   -6.735   1.00 39.10  ? 72  GLY C CA  1 
ATOM   4442  C C   . GLY C 1 67  ? -0.925  6.739   -5.725   1.00 52.44  ? 72  GLY C C   1 
ATOM   4443  O O   . GLY C 1 67  ? -0.604  6.841   -4.537   1.00 49.26  ? 72  GLY C O   1 
ATOM   4444  N N   . ASN C 1 68  ? -1.665  5.740   -6.189   1.00 53.70  ? 73  ASN C N   1 
ATOM   4445  C CA  . ASN C 1 68  ? -2.036  4.607   -5.353   1.00 51.99  ? 73  ASN C CA  1 
ATOM   4446  C C   . ASN C 1 68  ? -0.767  3.899   -4.888   1.00 54.42  ? 73  ASN C C   1 
ATOM   4447  O O   . ASN C 1 68  ? 0.046   3.491   -5.731   1.00 59.68  ? 73  ASN C O   1 
ATOM   4448  C CB  . ASN C 1 68  ? -2.934  3.658   -6.150   1.00 55.85  ? 73  ASN C CB  1 
ATOM   4449  C CG  . ASN C 1 68  ? -3.517  2.532   -5.308   1.00 60.20  ? 73  ASN C CG  1 
ATOM   4450  O OD1 . ASN C 1 68  ? -2.872  2.007   -4.401   1.00 68.47  ? 73  ASN C OD1 1 
ATOM   4451  N ND2 . ASN C 1 68  ? -4.749  2.149   -5.622   1.00 58.09  ? 73  ASN C ND2 1 
ATOM   4452  N N   . PRO C 1 69  ? -0.546  3.749   -3.579   1.00 58.04  ? 74  PRO C N   1 
ATOM   4453  C CA  . PRO C 1 69  ? 0.691   3.093   -3.122   1.00 65.07  ? 74  PRO C CA  1 
ATOM   4454  C C   . PRO C 1 69  ? 0.795   1.639   -3.544   1.00 61.79  ? 74  PRO C C   1 
ATOM   4455  O O   . PRO C 1 69  ? 1.908   1.144   -3.762   1.00 72.26  ? 74  PRO C O   1 
ATOM   4456  C CB  . PRO C 1 69  ? 0.621   3.242   -1.597   1.00 53.73  ? 74  PRO C CB  1 
ATOM   4457  C CG  . PRO C 1 69  ? -0.831  3.379   -1.301   1.00 53.68  ? 74  PRO C CG  1 
ATOM   4458  C CD  . PRO C 1 69  ? -1.419  4.130   -2.457   1.00 48.21  ? 74  PRO C CD  1 
ATOM   4459  N N   . MET C 1 70  ? -0.334  0.938   -3.668   1.00 69.32  ? 75  MET C N   1 
ATOM   4460  C CA  . MET C 1 70  ? -0.313  -0.444  -4.132   1.00 69.34  ? 75  MET C CA  1 
ATOM   4461  C C   . MET C 1 70  ? 0.092   -0.553  -5.597   1.00 64.63  ? 75  MET C C   1 
ATOM   4462  O O   . MET C 1 70  ? 0.463   -1.642  -6.045   1.00 75.05  ? 75  MET C O   1 
ATOM   4463  C CB  . MET C 1 70  ? -1.683  -1.090  -3.907   1.00 69.48  ? 75  MET C CB  1 
ATOM   4464  C CG  . MET C 1 70  ? -2.139  -1.063  -2.451   1.00 79.01  ? 75  MET C CG  1 
ATOM   4465  S SD  . MET C 1 70  ? -3.934  -1.107  -2.246   1.00 82.15  ? 75  MET C SD  1 
ATOM   4466  C CE  . MET C 1 70  ? -4.258  -2.867  -2.237   1.00 72.68  ? 75  MET C CE  1 
ATOM   4467  N N   . CYS C 1 71  ? 0.028   0.544   -6.349   1.00 74.45  ? 76  CYS C N   1 
ATOM   4468  C CA  . CYS C 1 71  ? 0.519   0.560   -7.717   1.00 75.24  ? 76  CYS C CA  1 
ATOM   4469  C C   . CYS C 1 71  ? 2.033   0.750   -7.727   1.00 86.01  ? 76  CYS C C   1 
ATOM   4470  O O   . CYS C 1 71  ? 2.694   0.789   -6.686   1.00 89.75  ? 76  CYS C O   1 
ATOM   4471  C CB  . CYS C 1 71  ? -0.162  1.663   -8.527   1.00 71.04  ? 76  CYS C CB  1 
ATOM   4472  S SG  . CYS C 1 71  ? -1.912  1.393   -8.884   1.00 98.58  ? 76  CYS C SG  1 
ATOM   4473  N N   . ASP C 1 72  ? 2.586   0.868   -8.929   1.00 103.68 ? 77  ASP C N   1 
ATOM   4474  C CA  . ASP C 1 72  ? 3.993   1.186   -9.096   1.00 112.93 ? 77  ASP C CA  1 
ATOM   4475  C C   . ASP C 1 72  ? 4.230   2.677   -8.877   1.00 112.31 ? 77  ASP C C   1 
ATOM   4476  O O   . ASP C 1 72  ? 3.304   3.492   -8.889   1.00 101.80 ? 77  ASP C O   1 
ATOM   4477  C CB  . ASP C 1 72  ? 4.474   0.775   -10.488  1.00 102.32 ? 77  ASP C CB  1 
ATOM   4478  C CG  . ASP C 1 72  ? 5.081   -0.613  -10.508  1.00 112.26 ? 77  ASP C CG  1 
ATOM   4479  O OD1 . ASP C 1 72  ? 6.149   -0.786  -11.134  1.00 122.36 ? 77  ASP C OD1 1 
ATOM   4480  O OD2 . ASP C 1 72  ? 4.502   -1.527  -9.881   1.00 106.31 ? 77  ASP C OD2 1 
ATOM   4481  N N   . GLU C 1 73  ? 5.496   3.025   -8.668   1.00 115.58 ? 78  GLU C N   1 
ATOM   4482  C CA  . GLU C 1 73  ? 5.871   4.420   -8.527   1.00 102.99 ? 78  GLU C CA  1 
ATOM   4483  C C   . GLU C 1 73  ? 5.797   5.123   -9.880   1.00 97.07  ? 78  GLU C C   1 
ATOM   4484  O O   . GLU C 1 73  ? 5.658   4.496   -10.934  1.00 108.38 ? 78  GLU C O   1 
ATOM   4485  C CB  . GLU C 1 73  ? 7.276   4.542   -7.934   1.00 103.61 ? 78  GLU C CB  1 
ATOM   4486  C CG  . GLU C 1 73  ? 7.337   4.387   -6.419   1.00 102.12 ? 78  GLU C CG  1 
ATOM   4487  C CD  . GLU C 1 73  ? 6.882   3.020   -5.939   1.00 111.87 ? 78  GLU C CD  1 
ATOM   4488  O OE1 . GLU C 1 73  ? 7.002   2.043   -6.709   1.00 114.84 ? 78  GLU C OE1 1 
ATOM   4489  O OE2 . GLU C 1 73  ? 6.400   2.924   -4.790   1.00 101.41 ? 78  GLU C OE2 1 
ATOM   4490  N N   . PHE C 1 74  ? 5.877   6.450   -9.839   1.00 87.83  ? 79  PHE C N   1 
ATOM   4491  C CA  . PHE C 1 74  ? 5.856   7.251   -11.058  1.00 103.24 ? 79  PHE C CA  1 
ATOM   4492  C C   . PHE C 1 74  ? 7.158   7.032   -11.820  1.00 102.26 ? 79  PHE C C   1 
ATOM   4493  O O   . PHE C 1 74  ? 8.231   7.424   -11.350  1.00 100.30 ? 79  PHE C O   1 
ATOM   4494  C CB  . PHE C 1 74  ? 5.656   8.724   -10.711  1.00 83.89  ? 79  PHE C CB  1 
ATOM   4495  C CG  . PHE C 1 74  ? 5.331   9.586   -11.895  1.00 89.21  ? 79  PHE C CG  1 
ATOM   4496  C CD1 . PHE C 1 74  ? 6.275   10.454  -12.417  1.00 91.65  ? 79  PHE C CD1 1 
ATOM   4497  C CD2 . PHE C 1 74  ? 4.079   9.527   -12.486  1.00 86.52  ? 79  PHE C CD2 1 
ATOM   4498  C CE1 . PHE C 1 74  ? 5.975   11.252  -13.509  1.00 102.59 ? 79  PHE C CE1 1 
ATOM   4499  C CE2 . PHE C 1 74  ? 3.773   10.319  -13.575  1.00 92.95  ? 79  PHE C CE2 1 
ATOM   4500  C CZ  . PHE C 1 74  ? 4.722   11.183  -14.088  1.00 86.81  ? 79  PHE C CZ  1 
ATOM   4501  N N   . ILE C 1 75  ? 7.070   6.406   -12.995  1.00 94.91  ? 80  ILE C N   1 
ATOM   4502  C CA  . ILE C 1 75  ? 8.255   6.037   -13.763  1.00 94.70  ? 80  ILE C CA  1 
ATOM   4503  C C   . ILE C 1 75  ? 8.573   7.055   -14.855  1.00 105.64 ? 80  ILE C C   1 
ATOM   4504  O O   . ILE C 1 75  ? 9.403   6.779   -15.728  1.00 109.93 ? 80  ILE C O   1 
ATOM   4505  C CB  . ILE C 1 75  ? 8.124   4.624   -14.355  1.00 92.15  ? 80  ILE C CB  1 
ATOM   4506  C CG1 . ILE C 1 75  ? 7.088   4.602   -15.480  1.00 102.05 ? 80  ILE C CG1 1 
ATOM   4507  C CG2 . ILE C 1 75  ? 7.763   3.620   -13.267  1.00 83.73  ? 80  ILE C CG2 1 
ATOM   4508  C CD1 . ILE C 1 75  ? 7.396   3.586   -16.561  1.00 96.21  ? 80  ILE C CD1 1 
ATOM   4509  N N   . ARG C 1 76  ? 7.934   8.227   -14.826  1.00 97.99  ? 81  ARG C N   1 
ATOM   4510  C CA  . ARG C 1 76  ? 8.330   9.385   -15.632  1.00 97.83  ? 81  ARG C CA  1 
ATOM   4511  C C   . ARG C 1 76  ? 8.287   9.073   -17.134  1.00 101.90 ? 81  ARG C C   1 
ATOM   4512  O O   . ARG C 1 76  ? 9.309   8.990   -17.821  1.00 109.10 ? 81  ARG C O   1 
ATOM   4513  C CB  . ARG C 1 76  ? 9.714   9.887   -15.198  1.00 94.63  ? 81  ARG C CB  1 
ATOM   4514  C CG  . ARG C 1 76  ? 10.126  11.222  -15.802  1.00 102.71 ? 81  ARG C CG  1 
ATOM   4515  C CD  . ARG C 1 76  ? 8.962   12.203  -15.835  1.00 110.73 ? 81  ARG C CD  1 
ATOM   4516  N NE  . ARG C 1 76  ? 9.353   13.505  -16.364  1.00 108.75 ? 81  ARG C NE  1 
ATOM   4517  C CZ  . ARG C 1 76  ? 9.591   13.753  -17.645  1.00 110.56 ? 81  ARG C CZ  1 
ATOM   4518  N NH1 . ARG C 1 76  ? 9.522   12.799  -18.557  1.00 116.94 ? 81  ARG C NH1 1 
ATOM   4519  N NH2 . ARG C 1 76  ? 9.912   14.988  -18.018  1.00 102.11 ? 81  ARG C NH2 1 
ATOM   4520  N N   . VAL C 1 77  ? 7.068   8.871   -17.621  1.00 96.72  ? 82  VAL C N   1 
ATOM   4521  C CA  . VAL C 1 77  ? 6.799   8.798   -19.054  1.00 93.00  ? 82  VAL C CA  1 
ATOM   4522  C C   . VAL C 1 77  ? 6.528   10.216  -19.551  1.00 87.80  ? 82  VAL C C   1 
ATOM   4523  O O   . VAL C 1 77  ? 5.536   10.828  -19.121  1.00 83.73  ? 82  VAL C O   1 
ATOM   4524  C CB  . VAL C 1 77  ? 5.614   7.875   -19.363  1.00 90.24  ? 82  VAL C CB  1 
ATOM   4525  C CG1 . VAL C 1 77  ? 5.310   7.884   -20.856  1.00 71.75  ? 82  VAL C CG1 1 
ATOM   4526  C CG2 . VAL C 1 77  ? 5.902   6.459   -18.882  1.00 88.34  ? 82  VAL C CG2 1 
ATOM   4527  N N   . PRO C 1 78  ? 7.364   10.769  -20.442  1.00 76.45  ? 83  PRO C N   1 
ATOM   4528  C CA  . PRO C 1 78  ? 7.155   12.151  -20.901  1.00 81.60  ? 83  PRO C CA  1 
ATOM   4529  C C   . PRO C 1 78  ? 6.024   12.303  -21.906  1.00 81.58  ? 83  PRO C C   1 
ATOM   4530  O O   . PRO C 1 78  ? 5.307   13.309  -21.896  1.00 69.17  ? 83  PRO C O   1 
ATOM   4531  C CB  . PRO C 1 78  ? 8.503   12.512  -21.537  1.00 83.21  ? 83  PRO C CB  1 
ATOM   4532  C CG  . PRO C 1 78  ? 9.072   11.204  -21.971  1.00 92.58  ? 83  PRO C CG  1 
ATOM   4533  C CD  . PRO C 1 78  ? 8.613   10.189  -20.961  1.00 73.53  ? 83  PRO C CD  1 
ATOM   4534  N N   . GLU C 1 79  A 5.859   11.317  -22.785  1.00 62.06  ? 83  GLU C N   1 
ATOM   4535  C CA  . GLU C 1 79  A 4.905   11.418  -23.879  1.00 61.09  ? 83  GLU C CA  1 
ATOM   4536  C C   . GLU C 1 79  A 4.448   10.020  -24.268  1.00 61.59  ? 83  GLU C C   1 
ATOM   4537  O O   . GLU C 1 79  A 5.208   9.053   -24.165  1.00 71.13  ? 83  GLU C O   1 
ATOM   4538  C CB  . GLU C 1 79  A 5.526   12.158  -25.075  1.00 57.32  ? 83  GLU C CB  1 
ATOM   4539  C CG  . GLU C 1 79  A 5.161   11.611  -26.448  1.00 81.30  ? 83  GLU C CG  1 
ATOM   4540  C CD  . GLU C 1 79  A 5.679   12.479  -27.582  1.00 88.98  ? 83  GLU C CD  1 
ATOM   4541  O OE1 . GLU C 1 79  A 4.904   12.756  -28.524  1.00 88.76  ? 83  GLU C OE1 1 
ATOM   4542  O OE2 . GLU C 1 79  A 6.857   12.891  -27.528  1.00 95.21  ? 83  GLU C OE2 1 
ATOM   4543  N N   . TRP C 1 80  ? 3.192   9.918   -24.699  1.00 52.80  ? 84  TRP C N   1 
ATOM   4544  C CA  . TRP C 1 80  ? 2.649   8.644   -25.143  1.00 52.06  ? 84  TRP C CA  1 
ATOM   4545  C C   . TRP C 1 80  ? 1.614   8.888   -26.231  1.00 60.27  ? 84  TRP C C   1 
ATOM   4546  O O   . TRP C 1 80  ? 1.061   9.984   -26.359  1.00 54.91  ? 84  TRP C O   1 
ATOM   4547  C CB  . TRP C 1 80  ? 2.044   7.850   -23.980  1.00 51.43  ? 84  TRP C CB  1 
ATOM   4548  C CG  . TRP C 1 80  ? 0.944   8.556   -23.244  1.00 53.02  ? 84  TRP C CG  1 
ATOM   4549  C CD1 . TRP C 1 80  ? -0.389  8.521   -23.533  1.00 52.10  ? 84  TRP C CD1 1 
ATOM   4550  C CD2 . TRP C 1 80  ? 1.080   9.382   -22.079  1.00 57.37  ? 84  TRP C CD2 1 
ATOM   4551  N NE1 . TRP C 1 80  ? -1.090  9.282   -22.629  1.00 49.86  ? 84  TRP C NE1 1 
ATOM   4552  C CE2 . TRP C 1 80  ? -0.212  9.820   -21.725  1.00 55.29  ? 84  TRP C CE2 1 
ATOM   4553  C CE3 . TRP C 1 80  ? 2.168   9.797   -21.305  1.00 49.92  ? 84  TRP C CE3 1 
ATOM   4554  C CZ2 . TRP C 1 80  ? -0.445  10.649  -20.631  1.00 53.10  ? 84  TRP C CZ2 1 
ATOM   4555  C CZ3 . TRP C 1 80  ? 1.935   10.623  -20.220  1.00 53.93  ? 84  TRP C CZ3 1 
ATOM   4556  C CH2 . TRP C 1 80  ? 0.640   11.042  -19.895  1.00 55.96  ? 84  TRP C CH2 1 
ATOM   4557  N N   . SER C 1 81  ? 1.367   7.845   -27.025  1.00 56.43  ? 85  SER C N   1 
ATOM   4558  C CA  . SER C 1 81  ? 0.446   7.922   -28.153  1.00 53.11  ? 85  SER C CA  1 
ATOM   4559  C C   . SER C 1 81  ? -0.917  7.318   -27.858  1.00 48.66  ? 85  SER C C   1 
ATOM   4560  O O   . SER C 1 81  ? -1.919  7.778   -28.416  1.00 53.23  ? 85  SER C O   1 
ATOM   4561  C CB  . SER C 1 81  ? 1.047   7.219   -29.375  1.00 60.22  ? 85  SER C CB  1 
ATOM   4562  O OG  . SER C 1 81  ? 1.356   5.869   -29.076  1.00 53.78  ? 85  SER C OG  1 
ATOM   4563  N N   . TYR C 1 82  ? -0.976  6.294   -27.011  1.00 49.01  ? 86  TYR C N   1 
ATOM   4564  C CA  . TYR C 1 82  ? -2.239  5.744   -26.542  1.00 40.30  ? 86  TYR C CA  1 
ATOM   4565  C C   . TYR C 1 82  ? -1.977  5.045   -25.217  1.00 47.30  ? 86  TYR C C   1 
ATOM   4566  O O   . TYR C 1 82  ? -0.830  4.795   -24.842  1.00 55.28  ? 86  TYR C O   1 
ATOM   4567  C CB  . TYR C 1 82  ? -2.873  4.801   -27.575  1.00 56.10  ? 86  TYR C CB  1 
ATOM   4568  C CG  . TYR C 1 82  ? -2.088  3.542   -27.876  1.00 52.56  ? 86  TYR C CG  1 
ATOM   4569  C CD1 . TYR C 1 82  ? -0.953  3.579   -28.676  1.00 56.58  ? 86  TYR C CD1 1 
ATOM   4570  C CD2 . TYR C 1 82  ? -2.501  2.311   -27.386  1.00 52.76  ? 86  TYR C CD2 1 
ATOM   4571  C CE1 . TYR C 1 82  ? -0.241  2.427   -28.963  1.00 49.28  ? 86  TYR C CE1 1 
ATOM   4572  C CE2 . TYR C 1 82  ? -1.798  1.156   -27.670  1.00 50.31  ? 86  TYR C CE2 1 
ATOM   4573  C CZ  . TYR C 1 82  ? -0.667  1.220   -28.455  1.00 51.50  ? 86  TYR C CZ  1 
ATOM   4574  O OH  . TYR C 1 82  ? 0.036   0.071   -28.735  1.00 56.73  ? 86  TYR C OH  1 
ATOM   4575  N N   . ILE C 1 83  ? -3.058  4.757   -24.497  1.00 44.42  ? 87  ILE C N   1 
ATOM   4576  C CA  . ILE C 1 83  ? -2.994  4.162   -23.168  1.00 46.48  ? 87  ILE C CA  1 
ATOM   4577  C C   . ILE C 1 83  ? -3.487  2.725   -23.257  1.00 56.01  ? 87  ILE C C   1 
ATOM   4578  O O   . ILE C 1 83  ? -4.518  2.453   -23.885  1.00 56.86  ? 87  ILE C O   1 
ATOM   4579  C CB  . ILE C 1 83  ? -3.823  4.966   -22.151  1.00 47.05  ? 87  ILE C CB  1 
ATOM   4580  C CG1 . ILE C 1 83  ? -3.208  6.351   -21.939  1.00 52.56  ? 87  ILE C CG1 1 
ATOM   4581  C CG2 . ILE C 1 83  ? -3.928  4.218   -20.829  1.00 43.38  ? 87  ILE C CG2 1 
ATOM   4582  C CD1 . ILE C 1 83  ? -3.947  7.193   -20.922  1.00 49.97  ? 87  ILE C CD1 1 
ATOM   4583  N N   . VAL C 1 84  ? -2.745  1.807   -22.642  1.00 52.51  ? 88  VAL C N   1 
ATOM   4584  C CA  . VAL C 1 84  ? -3.130  0.403   -22.566  1.00 53.26  ? 88  VAL C CA  1 
ATOM   4585  C C   . VAL C 1 84  ? -3.486  0.103   -21.119  1.00 56.81  ? 88  VAL C C   1 
ATOM   4586  O O   . VAL C 1 84  ? -2.624  0.143   -20.232  1.00 54.80  ? 88  VAL C O   1 
ATOM   4587  C CB  . VAL C 1 84  ? -2.019  -0.531  -23.065  1.00 60.94  ? 88  VAL C CB  1 
ATOM   4588  C CG1 . VAL C 1 84  ? -2.488  -1.975  -23.015  1.00 51.23  ? 88  VAL C CG1 1 
ATOM   4589  C CG2 . VAL C 1 84  ? -1.601  -0.158  -24.472  1.00 43.36  ? 88  VAL C CG2 1 
ATOM   4590  N N   . GLU C 1 85  ? -4.758  -0.192  -20.878  1.00 67.41  ? 89  GLU C N   1 
ATOM   4591  C CA  . GLU C 1 85  ? -5.235  -0.677  -19.594  1.00 58.31  ? 89  GLU C CA  1 
ATOM   4592  C C   . GLU C 1 85  ? -5.582  -2.153  -19.713  1.00 63.96  ? 89  GLU C C   1 
ATOM   4593  O O   . GLU C 1 85  ? -5.982  -2.627  -20.781  1.00 58.04  ? 89  GLU C O   1 
ATOM   4594  C CB  . GLU C 1 85  ? -6.473  0.095   -19.125  1.00 61.89  ? 89  GLU C CB  1 
ATOM   4595  C CG  . GLU C 1 85  ? -6.195  1.317   -18.269  1.00 71.15  ? 89  GLU C CG  1 
ATOM   4596  C CD  . GLU C 1 85  ? -7.473  1.944   -17.738  1.00 79.85  ? 89  GLU C CD  1 
ATOM   4597  O OE1 . GLU C 1 85  ? -8.543  1.722   -18.348  1.00 69.10  ? 89  GLU C OE1 1 
ATOM   4598  O OE2 . GLU C 1 85  ? -7.412  2.649   -16.707  1.00 72.33  ? 89  GLU C OE2 1 
ATOM   4599  N N   . ARG C 1 86  ? -5.417  -2.881  -18.614  1.00 57.94  ? 90  ARG C N   1 
ATOM   4600  C CA  . ARG C 1 86  ? -5.959  -4.227  -18.563  1.00 64.43  ? 90  ARG C CA  1 
ATOM   4601  C C   . ARG C 1 86  ? -7.480  -4.164  -18.453  1.00 64.99  ? 90  ARG C C   1 
ATOM   4602  O O   . ARG C 1 86  ? -8.063  -3.126  -18.123  1.00 64.01  ? 90  ARG C O   1 
ATOM   4603  C CB  . ARG C 1 86  ? -5.361  -5.011  -17.395  1.00 67.64  ? 90  ARG C CB  1 
ATOM   4604  C CG  . ARG C 1 86  ? -3.983  -5.576  -17.693  1.00 69.69  ? 90  ARG C CG  1 
ATOM   4605  C CD  . ARG C 1 86  ? -3.550  -6.592  -16.650  1.00 78.43  ? 90  ARG C CD  1 
ATOM   4606  N NE  . ARG C 1 86  ? -2.734  -7.646  -17.239  1.00 102.03 ? 90  ARG C NE  1 
ATOM   4607  C CZ  . ARG C 1 86  ? -3.188  -8.848  -17.570  1.00 85.44  ? 90  ARG C CZ  1 
ATOM   4608  N NH1 . ARG C 1 86  ? -4.444  -9.198  -17.344  1.00 92.13  ? 90  ARG C NH1 1 
ATOM   4609  N NH2 . ARG C 1 86  ? -2.361  -9.721  -18.139  1.00 77.83  ? 90  ARG C NH2 1 
ATOM   4610  N N   . ALA C 1 87  ? -8.126  -5.294  -18.754  1.00 70.30  ? 91  ALA C N   1 
ATOM   4611  C CA  . ALA C 1 87  ? -9.585  -5.332  -18.780  1.00 68.06  ? 91  ALA C CA  1 
ATOM   4612  C C   . ALA C 1 87  ? -10.171 -4.907  -17.440  1.00 68.95  ? 91  ALA C C   1 
ATOM   4613  O O   . ALA C 1 87  ? -11.076 -4.067  -17.381  1.00 73.36  ? 91  ALA C O   1 
ATOM   4614  C CB  . ALA C 1 87  ? -10.066 -6.732  -19.162  1.00 60.02  ? 91  ALA C CB  1 
ATOM   4615  N N   . ASN C 1 88  ? -9.657  -5.470  -16.348  1.00 74.86  ? 92  ASN C N   1 
ATOM   4616  C CA  . ASN C 1 88  ? -10.079 -5.112  -14.996  1.00 70.80  ? 92  ASN C CA  1 
ATOM   4617  C C   . ASN C 1 88  ? -8.831  -4.838  -14.170  1.00 71.14  ? 92  ASN C C   1 
ATOM   4618  O O   . ASN C 1 88  ? -8.285  -5.750  -13.534  1.00 88.07  ? 92  ASN C O   1 
ATOM   4619  C CB  . ASN C 1 88  ? -10.929 -6.216  -14.370  1.00 74.28  ? 92  ASN C CB  1 
ATOM   4620  C CG  . ASN C 1 88  ? -12.117 -6.595  -15.231  1.00 81.95  ? 92  ASN C CG  1 
ATOM   4621  O OD1 . ASN C 1 88  ? -12.221 -7.728  -15.701  1.00 82.38  ? 92  ASN C OD1 1 
ATOM   4622  N ND2 . ASN C 1 88  ? -13.022 -5.645  -15.444  1.00 84.70  ? 92  ASN C ND2 1 
ATOM   4623  N N   . PRO C 1 89  ? -8.337  -3.599  -14.173  1.00 83.19  ? 93  PRO C N   1 
ATOM   4624  C CA  . PRO C 1 89  ? -7.160  -3.278  -13.355  1.00 71.23  ? 93  PRO C CA  1 
ATOM   4625  C C   . PRO C 1 89  ? -7.425  -3.555  -11.883  1.00 69.79  ? 93  PRO C C   1 
ATOM   4626  O O   . PRO C 1 89  ? -8.501  -3.260  -11.358  1.00 73.20  ? 93  PRO C O   1 
ATOM   4627  C CB  . PRO C 1 89  ? -6.939  -1.784  -13.620  1.00 62.60  ? 93  PRO C CB  1 
ATOM   4628  C CG  . PRO C 1 89  ? -7.619  -1.524  -14.932  1.00 76.93  ? 93  PRO C CG  1 
ATOM   4629  C CD  . PRO C 1 89  ? -8.803  -2.443  -14.957  1.00 66.18  ? 93  PRO C CD  1 
ATOM   4630  N N   . ALA C 1 90  ? -6.424  -4.134  -11.216  1.00 62.16  ? 94  ALA C N   1 
ATOM   4631  C CA  . ALA C 1 90  ? -6.607  -4.552  -9.830   1.00 64.23  ? 94  ALA C CA  1 
ATOM   4632  C C   . ALA C 1 90  ? -6.602  -3.362  -8.878   1.00 69.12  ? 94  ALA C C   1 
ATOM   4633  O O   . ALA C 1 90  ? -7.427  -3.293  -7.959   1.00 80.64  ? 94  ALA C O   1 
ATOM   4634  C CB  . ALA C 1 90  ? -5.524  -5.556  -9.441   1.00 56.62  ? 94  ALA C CB  1 
ATOM   4635  N N   . ASN C 1 91  ? -5.686  -2.419  -9.079   1.00 61.50  ? 95  ASN C N   1 
ATOM   4636  C CA  . ASN C 1 91  ? -5.490  -1.294  -8.166   1.00 68.38  ? 95  ASN C CA  1 
ATOM   4637  C C   . ASN C 1 91  ? -6.055  -0.039  -8.820   1.00 66.41  ? 95  ASN C C   1 
ATOM   4638  O O   . ASN C 1 91  ? -5.430  0.543   -9.711   1.00 65.03  ? 95  ASN C O   1 
ATOM   4639  C CB  . ASN C 1 91  ? -4.011  -1.123  -7.831   1.00 67.97  ? 95  ASN C CB  1 
ATOM   4640  C CG  . ASN C 1 91  ? -3.335  -2.433  -7.485   1.00 53.87  ? 95  ASN C CG  1 
ATOM   4641  O OD1 . ASN C 1 91  ? -2.479  -2.918  -8.225   1.00 66.88  ? 95  ASN C OD1 1 
ATOM   4642  N ND2 . ASN C 1 91  ? -3.711  -3.009  -6.352   1.00 62.86  ? 95  ASN C ND2 1 
ATOM   4643  N N   . ASP C 1 92  ? -7.240  0.379   -8.377   1.00 65.88  ? 96  ASP C N   1 
ATOM   4644  C CA  . ASP C 1 92  ? -7.884  1.565   -8.926   1.00 57.02  ? 96  ASP C CA  1 
ATOM   4645  C C   . ASP C 1 92  ? -8.017  2.686   -7.904   1.00 58.35  ? 96  ASP C C   1 
ATOM   4646  O O   . ASP C 1 92  ? -7.429  3.757   -8.075   1.00 76.69  ? 96  ASP C O   1 
ATOM   4647  C CB  . ASP C 1 92  ? -9.262  1.177   -9.480   1.00 49.37  ? 96  ASP C CB  1 
ATOM   4648  C CG  . ASP C 1 92  ? -10.145 2.378   -9.737   1.00 64.93  ? 96  ASP C CG  1 
ATOM   4649  O OD1 . ASP C 1 92  ? -9.690  3.312   -10.433  1.00 65.50  ? 96  ASP C OD1 1 
ATOM   4650  O OD2 . ASP C 1 92  ? -11.298 2.381   -9.253   1.00 63.84  ? 96  ASP C OD2 1 
ATOM   4651  N N   . LEU C 1 93  A -8.736  2.452   -6.812   1.00 57.87  ? 96  LEU C N   1 
ATOM   4652  C CA  . LEU C 1 93  A -8.916  3.449   -5.758   1.00 62.45  ? 96  LEU C CA  1 
ATOM   4653  C C   . LEU C 1 93  A -8.843  2.690   -4.439   1.00 56.17  ? 96  LEU C C   1 
ATOM   4654  O O   . LEU C 1 93  A -9.835  2.096   -4.006   1.00 60.94  ? 96  LEU C O   1 
ATOM   4655  C CB  . LEU C 1 93  A -10.235 4.203   -5.896   1.00 64.65  ? 96  LEU C CB  1 
ATOM   4656  C CG  . LEU C 1 93  A -10.366 5.261   -6.995   1.00 70.84  ? 96  LEU C CG  1 
ATOM   4657  C CD1 . LEU C 1 93  A -11.772 5.849   -7.001   1.00 58.59  ? 96  LEU C CD1 1 
ATOM   4658  C CD2 . LEU C 1 93  A -9.328  6.361   -6.830   1.00 53.06  ? 96  LEU C CD2 1 
ATOM   4659  N N   . CYS C 1 94  ? -7.662  2.703   -3.818   1.00 51.38  ? 97  CYS C N   1 
ATOM   4660  C CA  . CYS C 1 94  ? -7.459  1.936   -2.594   1.00 60.98  ? 97  CYS C CA  1 
ATOM   4661  C C   . CYS C 1 94  ? -8.451  2.358   -1.517   1.00 55.08  ? 97  CYS C C   1 
ATOM   4662  O O   . CYS C 1 94  ? -9.082  1.513   -0.873   1.00 55.53  ? 97  CYS C O   1 
ATOM   4663  C CB  . CYS C 1 94  ? -6.017  2.097   -2.116   1.00 55.22  ? 97  CYS C CB  1 
ATOM   4664  S SG  . CYS C 1 94  ? -5.520  3.800   -1.776   1.00 80.36  ? 97  CYS C SG  1 
ATOM   4665  N N   . TYR C 1 95  ? -8.619  3.663   -1.319   1.00 46.14  ? 98  TYR C N   1 
ATOM   4666  C CA  . TYR C 1 95  ? -9.698  4.150   -0.474   1.00 57.05  ? 98  TYR C CA  1 
ATOM   4667  C C   . TYR C 1 95  ? -10.952 4.305   -1.322   1.00 50.54  ? 98  TYR C C   1 
ATOM   4668  O O   . TYR C 1 95  ? -10.907 4.994   -2.349   1.00 50.20  ? 98  TYR C O   1 
ATOM   4669  C CB  . TYR C 1 95  ? -9.334  5.470   0.183    1.00 48.41  ? 98  TYR C CB  1 
ATOM   4670  C CG  . TYR C 1 95  ? -10.180 5.762   1.401    1.00 42.99  ? 98  TYR C CG  1 
ATOM   4671  C CD1 . TYR C 1 95  ? -11.431 6.352   1.274    1.00 45.62  ? 98  TYR C CD1 1 
ATOM   4672  C CD2 . TYR C 1 95  ? -9.741  5.425   2.675    1.00 42.44  ? 98  TYR C CD2 1 
ATOM   4673  C CE1 . TYR C 1 95  ? -12.215 6.610   2.380    1.00 46.00  ? 98  TYR C CE1 1 
ATOM   4674  C CE2 . TYR C 1 95  ? -10.520 5.680   3.791    1.00 40.47  ? 98  TYR C CE2 1 
ATOM   4675  C CZ  . TYR C 1 95  ? -11.756 6.275   3.634    1.00 46.58  ? 98  TYR C CZ  1 
ATOM   4676  O OH  . TYR C 1 95  ? -12.540 6.536   4.731    1.00 43.92  ? 98  TYR C OH  1 
ATOM   4677  N N   . PRO C 1 96  ? -12.071 3.685   -0.947   1.00 52.40  ? 99  PRO C N   1 
ATOM   4678  C CA  . PRO C 1 96  ? -13.240 3.669   -1.834   1.00 46.83  ? 99  PRO C CA  1 
ATOM   4679  C C   . PRO C 1 96  ? -13.793 5.063   -2.086   1.00 47.58  ? 99  PRO C C   1 
ATOM   4680  O O   . PRO C 1 96  ? -13.693 5.961   -1.249   1.00 43.00  ? 99  PRO C O   1 
ATOM   4681  C CB  . PRO C 1 96  ? -14.247 2.796   -1.077   1.00 38.20  ? 99  PRO C CB  1 
ATOM   4682  C CG  . PRO C 1 96  ? -13.828 2.895   0.354    1.00 47.66  ? 99  PRO C CG  1 
ATOM   4683  C CD  . PRO C 1 96  ? -12.331 2.995   0.327    1.00 45.58  ? 99  PRO C CD  1 
ATOM   4684  N N   . GLY C 1 97  ? -14.381 5.232   -3.268   1.00 43.22  ? 100 GLY C N   1 
ATOM   4685  C CA  . GLY C 1 97  ? -14.938 6.507   -3.671   1.00 46.16  ? 100 GLY C CA  1 
ATOM   4686  C C   . GLY C 1 97  ? -15.074 6.615   -5.173   1.00 51.38  ? 100 GLY C C   1 
ATOM   4687  O O   . GLY C 1 97  ? -15.391 5.627   -5.841   1.00 52.45  ? 100 GLY C O   1 
ATOM   4688  N N   . SER C 1 98  ? -14.830 7.802   -5.723   1.00 50.00  ? 101 SER C N   1 
ATOM   4689  C CA  . SER C 1 98  ? -14.960 7.998   -7.159   1.00 50.65  ? 101 SER C CA  1 
ATOM   4690  C C   . SER C 1 98  ? -14.071 9.148   -7.606   1.00 54.65  ? 101 SER C C   1 
ATOM   4691  O O   . SER C 1 98  ? -13.600 9.953   -6.798   1.00 46.84  ? 101 SER C O   1 
ATOM   4692  C CB  . SER C 1 98  ? -16.413 8.275   -7.561   1.00 54.52  ? 101 SER C CB  1 
ATOM   4693  O OG  . SER C 1 98  ? -16.860 9.511   -7.025   1.00 51.68  ? 101 SER C OG  1 
ATOM   4694  N N   . LEU C 1 99  ? -13.844 9.206   -8.915   1.00 45.07  ? 102 LEU C N   1 
ATOM   4695  C CA  . LEU C 1 99  ? -13.189 10.332  -9.565   1.00 47.47  ? 102 LEU C CA  1 
ATOM   4696  C C   . LEU C 1 99  ? -14.171 10.913  -10.571  1.00 52.26  ? 102 LEU C C   1 
ATOM   4697  O O   . LEU C 1 99  ? -14.613 10.209  -11.486  1.00 45.26  ? 102 LEU C O   1 
ATOM   4698  C CB  . LEU C 1 99  ? -11.887 9.897   -10.241  1.00 38.23  ? 102 LEU C CB  1 
ATOM   4699  C CG  . LEU C 1 99  ? -11.103 10.928  -11.057  1.00 50.84  ? 102 LEU C CG  1 
ATOM   4700  C CD1 . LEU C 1 99  ? -10.838 12.188  -10.249  1.00 50.36  ? 102 LEU C CD1 1 
ATOM   4701  C CD2 . LEU C 1 99  ? -9.794  10.320  -11.533  1.00 41.02  ? 102 LEU C CD2 1 
ATOM   4702  N N   . ASN C 1 100 ? -14.517 12.186  -10.395  1.00 43.04  ? 103 ASN C N   1 
ATOM   4703  C CA  . ASN C 1 100 ? -15.556 12.811  -11.199  1.00 44.15  ? 103 ASN C CA  1 
ATOM   4704  C C   . ASN C 1 100 ? -15.100 12.991  -12.645  1.00 47.42  ? 103 ASN C C   1 
ATOM   4705  O O   . ASN C 1 100 ? -13.926 13.253  -12.922  1.00 47.01  ? 103 ASN C O   1 
ATOM   4706  C CB  . ASN C 1 100 ? -15.945 14.159  -10.588  1.00 55.13  ? 103 ASN C CB  1 
ATOM   4707  C CG  . ASN C 1 100 ? -17.128 14.802  -11.286  1.00 50.70  ? 103 ASN C CG  1 
ATOM   4708  O OD1 . ASN C 1 100 ? -16.980 15.804  -11.984  1.00 54.05  ? 103 ASN C OD1 1 
ATOM   4709  N ND2 . ASN C 1 100 ? -18.311 14.228  -11.098  1.00 47.58  ? 103 ASN C ND2 1 
ATOM   4710  N N   . ASP C 1 101 ? -16.051 12.845  -13.573  1.00 40.10  ? 104 ASP C N   1 
ATOM   4711  C CA  . ASP C 1 101 ? -15.787 12.990  -15.010  1.00 37.70  ? 104 ASP C CA  1 
ATOM   4712  C C   . ASP C 1 101 ? -14.624 12.104  -15.446  1.00 45.06  ? 104 ASP C C   1 
ATOM   4713  O O   . ASP C 1 101 ? -13.747 12.518  -16.209  1.00 44.70  ? 104 ASP C O   1 
ATOM   4714  C CB  . ASP C 1 101 ? -15.525 14.452  -15.382  1.00 49.09  ? 104 ASP C CB  1 
ATOM   4715  C CG  . ASP C 1 101 ? -16.769 15.315  -15.280  1.00 59.72  ? 104 ASP C CG  1 
ATOM   4716  O OD1 . ASP C 1 101 ? -17.863 14.828  -15.635  1.00 63.83  ? 104 ASP C OD1 1 
ATOM   4717  O OD2 . ASP C 1 101 ? -16.652 16.482  -14.846  1.00 79.05  ? 104 ASP C OD2 1 
ATOM   4718  N N   . TYR C 1 102 ? -14.624 10.864  -14.951  1.00 45.50  ? 105 TYR C N   1 
ATOM   4719  C CA  . TYR C 1 102 ? -13.498 9.964   -15.173  1.00 39.73  ? 105 TYR C CA  1 
ATOM   4720  C C   . TYR C 1 102 ? -13.298 9.668   -16.656  1.00 34.02  ? 105 TYR C C   1 
ATOM   4721  O O   . TYR C 1 102 ? -12.162 9.641   -17.144  1.00 44.61  ? 105 TYR C O   1 
ATOM   4722  C CB  . TYR C 1 102 ? -13.718 8.668   -14.391  1.00 43.26  ? 105 TYR C CB  1 
ATOM   4723  C CG  . TYR C 1 102 ? -12.510 7.765   -14.317  1.00 57.03  ? 105 TYR C CG  1 
ATOM   4724  C CD1 . TYR C 1 102 ? -11.223 8.283   -14.388  1.00 40.59  ? 105 TYR C CD1 1 
ATOM   4725  C CD2 . TYR C 1 102 ? -12.657 6.389   -14.181  1.00 53.46  ? 105 TYR C CD2 1 
ATOM   4726  C CE1 . TYR C 1 102 ? -10.117 7.459   -14.318  1.00 46.26  ? 105 TYR C CE1 1 
ATOM   4727  C CE2 . TYR C 1 102 ? -11.558 5.556   -14.111  1.00 43.35  ? 105 TYR C CE2 1 
ATOM   4728  C CZ  . TYR C 1 102 ? -10.291 6.096   -14.180  1.00 47.53  ? 105 TYR C CZ  1 
ATOM   4729  O OH  . TYR C 1 102 ? -9.197  5.268   -14.111  1.00 56.45  ? 105 TYR C OH  1 
ATOM   4730  N N   . GLU C 1 103 ? -14.391 9.440   -17.388  1.00 39.64  ? 106 GLU C N   1 
ATOM   4731  C CA  . GLU C 1 103 ? -14.277 9.016   -18.782  1.00 42.92  ? 106 GLU C CA  1 
ATOM   4732  C C   . GLU C 1 103 ? -13.768 10.145  -19.671  1.00 43.52  ? 106 GLU C C   1 
ATOM   4733  O O   . GLU C 1 103 ? -12.985 9.904   -20.597  1.00 43.00  ? 106 GLU C O   1 
ATOM   4734  C CB  . GLU C 1 103 ? -15.622 8.494   -19.287  1.00 45.04  ? 106 GLU C CB  1 
ATOM   4735  C CG  . GLU C 1 103 ? -16.136 7.254   -18.557  1.00 46.96  ? 106 GLU C CG  1 
ATOM   4736  C CD  . GLU C 1 103 ? -16.668 7.566   -17.169  1.00 59.79  ? 106 GLU C CD  1 
ATOM   4737  O OE1 . GLU C 1 103 ? -16.637 6.671   -16.298  1.00 67.97  ? 106 GLU C OE1 1 
ATOM   4738  O OE2 . GLU C 1 103 ? -17.109 8.714   -16.948  1.00 63.00  ? 106 GLU C OE2 1 
ATOM   4739  N N   . GLU C 1 104 ? -14.205 11.381  -19.417  1.00 42.43  ? 107 GLU C N   1 
ATOM   4740  C CA  . GLU C 1 104 ? -13.642 12.511  -20.150  1.00 41.12  ? 107 GLU C CA  1 
ATOM   4741  C C   . GLU C 1 104 ? -12.177 12.729  -19.795  1.00 32.79  ? 107 GLU C C   1 
ATOM   4742  O O   . GLU C 1 104 ? -11.386 13.134  -20.653  1.00 42.79  ? 107 GLU C O   1 
ATOM   4743  C CB  . GLU C 1 104 ? -14.453 13.782  -19.881  1.00 41.70  ? 107 GLU C CB  1 
ATOM   4744  C CG  . GLU C 1 104 ? -15.816 13.813  -20.563  1.00 41.00  ? 107 GLU C CG  1 
ATOM   4745  C CD  . GLU C 1 104 ? -15.720 13.952  -22.076  1.00 50.48  ? 107 GLU C CD  1 
ATOM   4746  O OE1 . GLU C 1 104 ? -14.992 14.850  -22.554  1.00 52.62  ? 107 GLU C OE1 1 
ATOM   4747  O OE2 . GLU C 1 104 ? -16.375 13.161  -22.789  1.00 48.55  ? 107 GLU C OE2 1 
ATOM   4748  N N   . LEU C 1 105 ? -11.802 12.468  -18.540  1.00 44.05  ? 108 LEU C N   1 
ATOM   4749  C CA  . LEU C 1 105 ? -10.403 12.583  -18.137  1.00 40.52  ? 108 LEU C CA  1 
ATOM   4750  C C   . LEU C 1 105 ? -9.537  11.548  -18.847  1.00 38.16  ? 108 LEU C C   1 
ATOM   4751  O O   . LEU C 1 105 ? -8.449  11.866  -19.341  1.00 47.29  ? 108 LEU C O   1 
ATOM   4752  C CB  . LEU C 1 105 ? -10.286 12.435  -16.621  1.00 44.78  ? 108 LEU C CB  1 
ATOM   4753  C CG  . LEU C 1 105 ? -8.877  12.510  -16.036  1.00 43.54  ? 108 LEU C CG  1 
ATOM   4754  C CD1 . LEU C 1 105 ? -8.216  13.824  -16.415  1.00 45.72  ? 108 LEU C CD1 1 
ATOM   4755  C CD2 . LEU C 1 105 ? -8.927  12.350  -14.526  1.00 43.82  ? 108 LEU C CD2 1 
ATOM   4756  N N   . LYS C 1 106 ? -10.004 10.297  -18.902  1.00 47.30  ? 109 LYS C N   1 
ATOM   4757  C CA  . LYS C 1 106 ? -9.254  9.259   -19.600  1.00 42.23  ? 109 LYS C CA  1 
ATOM   4758  C C   . LYS C 1 106 ? -9.144  9.569   -21.086  1.00 44.90  ? 109 LYS C C   1 
ATOM   4759  O O   . LYS C 1 106 ? -8.083  9.373   -21.691  1.00 51.40  ? 109 LYS C O   1 
ATOM   4760  C CB  . LYS C 1 106 ? -9.913  7.897   -19.376  1.00 42.07  ? 109 LYS C CB  1 
ATOM   4761  C CG  . LYS C 1 106 ? -9.799  7.392   -17.948  1.00 47.26  ? 109 LYS C CG  1 
ATOM   4762  C CD  . LYS C 1 106 ? -10.877 6.370   -17.605  1.00 50.74  ? 109 LYS C CD  1 
ATOM   4763  C CE  . LYS C 1 106 ? -10.544 4.978   -18.113  1.00 59.83  ? 109 LYS C CE  1 
ATOM   4764  N NZ  . LYS C 1 106 ? -10.865 4.791   -19.556  1.00 84.32  ? 109 LYS C NZ  1 
ATOM   4765  N N   . HIS C 1 107 ? -10.227 10.066  -21.690  1.00 38.47  ? 110 HIS C N   1 
ATOM   4766  C CA  . HIS C 1 107 ? -10.187 10.410  -23.107  1.00 49.54  ? 110 HIS C CA  1 
ATOM   4767  C C   . HIS C 1 107 ? -9.186  11.526  -23.377  1.00 48.48  ? 110 HIS C C   1 
ATOM   4768  O O   . HIS C 1 107 ? -8.460  11.486  -24.376  1.00 45.51  ? 110 HIS C O   1 
ATOM   4769  C CB  . HIS C 1 107 ? -11.577 10.813  -23.597  1.00 37.73  ? 110 HIS C CB  1 
ATOM   4770  C CG  . HIS C 1 107 ? -11.623 11.136  -25.056  1.00 53.33  ? 110 HIS C CG  1 
ATOM   4771  N ND1 . HIS C 1 107 ? -11.663 10.164  -26.032  1.00 52.21  ? 110 HIS C ND1 1 
ATOM   4772  C CD2 . HIS C 1 107 ? -11.615 12.323  -25.709  1.00 54.75  ? 110 HIS C CD2 1 
ATOM   4773  C CE1 . HIS C 1 107 ? -11.687 10.737  -27.221  1.00 53.96  ? 110 HIS C CE1 1 
ATOM   4774  N NE2 . HIS C 1 107 ? -11.658 12.046  -27.053  1.00 51.60  ? 110 HIS C NE2 1 
ATOM   4775  N N   . MET C 1 108 ? -9.138  12.535  -22.503  1.00 45.78  ? 111 MET C N   1 
ATOM   4776  C CA  . MET C 1 108 ? -8.163  13.608  -22.677  1.00 41.55  ? 111 MET C CA  1 
ATOM   4777  C C   . MET C 1 108 ? -6.738  13.097  -22.499  1.00 54.05  ? 111 MET C C   1 
ATOM   4778  O O   . MET C 1 108 ? -5.834  13.488  -23.246  1.00 47.66  ? 111 MET C O   1 
ATOM   4779  C CB  . MET C 1 108 ? -8.443  14.751  -21.700  1.00 37.01  ? 111 MET C CB  1 
ATOM   4780  C CG  . MET C 1 108 ? -7.375  15.845  -21.742  1.00 49.95  ? 111 MET C CG  1 
ATOM   4781  S SD  . MET C 1 108 ? -7.023  16.602  -20.146  1.00 70.59  ? 111 MET C SD  1 
ATOM   4782  C CE  . MET C 1 108 ? -8.429  17.695  -19.980  1.00 54.99  ? 111 MET C CE  1 
ATOM   4783  N N   . LEU C 1 109 ? -6.516  12.220  -21.521  1.00 51.18  ? 112 LEU C N   1 
ATOM   4784  C CA  . LEU C 1 109 ? -5.181  11.716  -21.229  1.00 47.59  ? 112 LEU C CA  1 
ATOM   4785  C C   . LEU C 1 109 ? -4.732  10.619  -22.186  1.00 55.40  ? 112 LEU C C   1 
ATOM   4786  O O   . LEU C 1 109 ? -3.599  10.142  -22.061  1.00 47.53  ? 112 LEU C O   1 
ATOM   4787  C CB  . LEU C 1 109 ? -5.116  11.195  -19.791  1.00 43.37  ? 112 LEU C CB  1 
ATOM   4788  C CG  . LEU C 1 109 ? -5.203  12.237  -18.676  1.00 46.99  ? 112 LEU C CG  1 
ATOM   4789  C CD1 . LEU C 1 109 ? -4.974  11.588  -17.324  1.00 39.41  ? 112 LEU C CD1 1 
ATOM   4790  C CD2 . LEU C 1 109 ? -4.203  13.351  -18.907  1.00 44.31  ? 112 LEU C CD2 1 
ATOM   4791  N N   . SER C 1 110 ? -5.583  10.213  -23.131  1.00 47.41  ? 113 SER C N   1 
ATOM   4792  C CA  . SER C 1 110 ? -5.253  9.096   -24.012  1.00 50.37  ? 113 SER C CA  1 
ATOM   4793  C C   . SER C 1 110 ? -4.006  9.369   -24.844  1.00 55.27  ? 113 SER C C   1 
ATOM   4794  O O   . SER C 1 110 ? -3.288  8.433   -25.211  1.00 50.15  ? 113 SER C O   1 
ATOM   4795  C CB  . SER C 1 110 ? -6.439  8.791   -24.926  1.00 46.31  ? 113 SER C CB  1 
ATOM   4796  O OG  . SER C 1 110 ? -6.752  9.914   -25.732  1.00 48.08  ? 113 SER C OG  1 
ATOM   4797  N N   . ARG C 1 111 ? -3.731  10.632  -25.156  1.00 52.33  ? 114 ARG C N   1 
ATOM   4798  C CA  . ARG C 1 111 ? -2.571  10.983  -25.971  1.00 48.57  ? 114 ARG C CA  1 
ATOM   4799  C C   . ARG C 1 111 ? -2.071  12.340  -25.505  1.00 53.49  ? 114 ARG C C   1 
ATOM   4800  O O   . ARG C 1 111 ? -2.757  13.350  -25.688  1.00 57.40  ? 114 ARG C O   1 
ATOM   4801  C CB  . ARG C 1 111 ? -2.933  11.006  -27.450  1.00 50.73  ? 114 ARG C CB  1 
ATOM   4802  C CG  . ARG C 1 111 ? -1.824  11.462  -28.376  1.00 46.41  ? 114 ARG C CG  1 
ATOM   4803  C CD  . ARG C 1 111 ? -2.289  11.332  -29.815  1.00 62.44  ? 114 ARG C CD  1 
ATOM   4804  N NE  . ARG C 1 111 ? -1.311  11.814  -30.780  1.00 79.71  ? 114 ARG C NE  1 
ATOM   4805  C CZ  . ARG C 1 111 ? -1.501  11.810  -32.092  1.00 81.42  ? 114 ARG C CZ  1 
ATOM   4806  N NH1 . ARG C 1 111 ? -2.622  11.352  -32.626  1.00 76.18  ? 114 ARG C NH1 1 
ATOM   4807  N NH2 . ARG C 1 111 ? -0.543  12.277  -32.889  1.00 74.77  ? 114 ARG C NH2 1 
ATOM   4808  N N   . ILE C 1 112 ? -0.881  12.363  -24.911  1.00 51.35  ? 115 ILE C N   1 
ATOM   4809  C CA  . ILE C 1 112 ? -0.325  13.563  -24.302  1.00 55.12  ? 115 ILE C CA  1 
ATOM   4810  C C   . ILE C 1 112 ? 1.071   13.793  -24.863  1.00 61.57  ? 115 ILE C C   1 
ATOM   4811  O O   . ILE C 1 112 ? 1.876   12.859  -24.943  1.00 55.71  ? 115 ILE C O   1 
ATOM   4812  C CB  . ILE C 1 112 ? -0.294  13.451  -22.766  1.00 52.41  ? 115 ILE C CB  1 
ATOM   4813  C CG1 . ILE C 1 112 ? -1.722  13.447  -22.216  1.00 64.12  ? 115 ILE C CG1 1 
ATOM   4814  C CG2 . ILE C 1 112 ? 0.506   14.584  -22.157  1.00 53.76  ? 115 ILE C CG2 1 
ATOM   4815  C CD1 . ILE C 1 112 ? -2.544  14.647  -22.646  1.00 51.20  ? 115 ILE C CD1 1 
ATOM   4816  N N   . ASN C 1 113 ? 1.350   15.037  -25.260  1.00 57.83  ? 116 ASN C N   1 
ATOM   4817  C CA  . ASN C 1 113 ? 2.635   15.374  -25.859  1.00 58.44  ? 116 ASN C CA  1 
ATOM   4818  C C   . ASN C 1 113 ? 3.707   15.661  -24.813  1.00 62.39  ? 116 ASN C C   1 
ATOM   4819  O O   . ASN C 1 113 ? 4.885   15.368  -25.048  1.00 63.35  ? 116 ASN C O   1 
ATOM   4820  C CB  . ASN C 1 113 ? 2.465   16.570  -26.797  1.00 56.91  ? 116 ASN C CB  1 
ATOM   4821  C CG  . ASN C 1 113 ? 3.765   16.992  -27.450  1.00 79.25  ? 116 ASN C CG  1 
ATOM   4822  O OD1 . ASN C 1 113 ? 4.251   18.102  -27.231  1.00 86.04  ? 116 ASN C OD1 1 
ATOM   4823  N ND2 . ASN C 1 113 ? 4.341   16.103  -28.251  1.00 79.31  ? 116 ASN C ND2 1 
ATOM   4824  N N   . HIS C 1 114 ? 3.332   16.228  -23.666  1.00 52.29  ? 117 HIS C N   1 
ATOM   4825  C CA  . HIS C 1 114 ? 4.273   16.438  -22.573  1.00 58.96  ? 117 HIS C CA  1 
ATOM   4826  C C   . HIS C 1 114 ? 3.537   16.307  -21.246  1.00 56.11  ? 117 HIS C C   1 
ATOM   4827  O O   . HIS C 1 114 ? 2.437   16.839  -21.081  1.00 53.11  ? 117 HIS C O   1 
ATOM   4828  C CB  . HIS C 1 114 ? 4.961   17.805  -22.667  1.00 65.36  ? 117 HIS C CB  1 
ATOM   4829  C CG  . HIS C 1 114 ? 6.008   18.026  -21.618  1.00 73.21  ? 117 HIS C CG  1 
ATOM   4830  N ND1 . HIS C 1 114 ? 5.883   18.978  -20.630  1.00 84.91  ? 117 HIS C ND1 1 
ATOM   4831  C CD2 . HIS C 1 114 ? 7.194   17.411  -21.399  1.00 73.48  ? 117 HIS C CD2 1 
ATOM   4832  C CE1 . HIS C 1 114 ? 6.949   18.944  -19.850  1.00 81.04  ? 117 HIS C CE1 1 
ATOM   4833  N NE2 . HIS C 1 114 ? 7.760   18.002  -20.295  1.00 85.10  ? 117 HIS C NE2 1 
ATOM   4834  N N   . PHE C 1 115 ? 4.163   15.608  -20.303  1.00 54.37  ? 118 PHE C N   1 
ATOM   4835  C CA  . PHE C 1 115 ? 3.536   15.272  -19.029  1.00 49.38  ? 118 PHE C CA  1 
ATOM   4836  C C   . PHE C 1 115 ? 4.622   15.244  -17.967  1.00 55.48  ? 118 PHE C C   1 
ATOM   4837  O O   . PHE C 1 115 ? 5.615   14.527  -18.123  1.00 70.10  ? 118 PHE C O   1 
ATOM   4838  C CB  . PHE C 1 115 ? 2.829   13.917  -19.128  1.00 58.47  ? 118 PHE C CB  1 
ATOM   4839  C CG  . PHE C 1 115 ? 1.829   13.657  -18.036  1.00 50.76  ? 118 PHE C CG  1 
ATOM   4840  C CD1 . PHE C 1 115 ? 0.612   14.320  -18.019  1.00 54.42  ? 118 PHE C CD1 1 
ATOM   4841  C CD2 . PHE C 1 115 ? 2.088   12.718  -17.050  1.00 55.81  ? 118 PHE C CD2 1 
ATOM   4842  C CE1 . PHE C 1 115 ? -0.317  14.071  -17.026  1.00 45.40  ? 118 PHE C CE1 1 
ATOM   4843  C CE2 . PHE C 1 115 ? 1.161   12.462  -16.055  1.00 51.73  ? 118 PHE C CE2 1 
ATOM   4844  C CZ  . PHE C 1 115 ? -0.045  13.138  -16.046  1.00 56.18  ? 118 PHE C CZ  1 
ATOM   4845  N N   . GLU C 1 116 ? 4.447   16.018  -16.897  1.00 50.33  ? 119 GLU C N   1 
ATOM   4846  C CA  . GLU C 1 116 ? 5.463   16.081  -15.852  1.00 48.26  ? 119 GLU C CA  1 
ATOM   4847  C C   . GLU C 1 116 ? 4.820   16.422  -14.518  1.00 51.69  ? 119 GLU C C   1 
ATOM   4848  O O   . GLU C 1 116 ? 4.106   17.424  -14.409  1.00 50.58  ? 119 GLU C O   1 
ATOM   4849  C CB  . GLU C 1 116 ? 6.540   17.116  -16.192  1.00 60.14  ? 119 GLU C CB  1 
ATOM   4850  C CG  . GLU C 1 116 ? 7.681   17.156  -15.189  1.00 71.61  ? 119 GLU C CG  1 
ATOM   4851  C CD  . GLU C 1 116 ? 8.596   18.348  -15.388  1.00 85.28  ? 119 GLU C CD  1 
ATOM   4852  O OE1 . GLU C 1 116 ? 8.256   19.231  -16.205  1.00 86.46  ? 119 GLU C OE1 1 
ATOM   4853  O OE2 . GLU C 1 116 ? 9.654   18.402  -14.727  1.00 84.09  ? 119 GLU C OE2 1 
ATOM   4854  N N   . LYS C 1 117 ? 5.090   15.601  -13.507  1.00 56.57  ? 120 LYS C N   1 
ATOM   4855  C CA  . LYS C 1 117 ? 4.595   15.864  -12.165  1.00 44.82  ? 120 LYS C CA  1 
ATOM   4856  C C   . LYS C 1 117 ? 5.438   16.943  -11.496  1.00 61.11  ? 120 LYS C C   1 
ATOM   4857  O O   . LYS C 1 117 ? 6.672   16.895  -11.538  1.00 63.71  ? 120 LYS C O   1 
ATOM   4858  C CB  . LYS C 1 117 ? 4.607   14.587  -11.325  1.00 54.12  ? 120 LYS C CB  1 
ATOM   4859  C CG  . LYS C 1 117 ? 3.987   14.764  -9.951   1.00 52.56  ? 120 LYS C CG  1 
ATOM   4860  C CD  . LYS C 1 117 ? 3.579   13.436  -9.330   1.00 53.01  ? 120 LYS C CD  1 
ATOM   4861  C CE  . LYS C 1 117 ? 4.755   12.721  -8.697   1.00 53.54  ? 120 LYS C CE  1 
ATOM   4862  N NZ  . LYS C 1 117 ? 4.329   11.445  -8.063   1.00 63.85  ? 120 LYS C NZ  1 
ATOM   4863  N N   . ILE C 1 118 ? 4.771   17.923  -10.888  1.00 48.59  ? 121 ILE C N   1 
ATOM   4864  C CA  . ILE C 1 118 ? 5.436   18.984  -10.147  1.00 49.99  ? 121 ILE C CA  1 
ATOM   4865  C C   . ILE C 1 118 ? 4.718   19.182  -8.822   1.00 47.19  ? 121 ILE C C   1 
ATOM   4866  O O   . ILE C 1 118 ? 3.517   18.926  -8.699   1.00 54.89  ? 121 ILE C O   1 
ATOM   4867  C CB  . ILE C 1 118 ? 5.480   20.317  -10.928  1.00 55.07  ? 121 ILE C CB  1 
ATOM   4868  C CG1 . ILE C 1 118 ? 4.067   20.754  -11.315  1.00 49.50  ? 121 ILE C CG1 1 
ATOM   4869  C CG2 . ILE C 1 118 ? 6.379   20.197  -12.148  1.00 51.00  ? 121 ILE C CG2 1 
ATOM   4870  C CD1 . ILE C 1 118 ? 3.979   22.192  -11.774  1.00 60.91  ? 121 ILE C CD1 1 
ATOM   4871  N N   . GLN C 1 119 ? 5.463   19.653  -7.828   1.00 58.20  ? 122 GLN C N   1 
ATOM   4872  C CA  . GLN C 1 119 ? 4.893   20.001  -6.536   1.00 49.78  ? 122 GLN C CA  1 
ATOM   4873  C C   . GLN C 1 119 ? 4.393   21.439  -6.579   1.00 48.68  ? 122 GLN C C   1 
ATOM   4874  O O   . GLN C 1 119 ? 5.133   22.347  -6.971   1.00 57.20  ? 122 GLN C O   1 
ATOM   4875  C CB  . GLN C 1 119 ? 5.927   19.829  -5.423   1.00 45.34  ? 122 GLN C CB  1 
ATOM   4876  C CG  . GLN C 1 119 ? 5.386   20.134  -4.032   1.00 60.01  ? 122 GLN C CG  1 
ATOM   4877  C CD  . GLN C 1 119 ? 6.413   19.904  -2.941   1.00 65.10  ? 122 GLN C CD  1 
ATOM   4878  O OE1 . GLN C 1 119 ? 7.383   20.652  -2.818   1.00 62.17  ? 122 GLN C OE1 1 
ATOM   4879  N NE2 . GLN C 1 119 ? 6.204   18.865  -2.141   1.00 57.82  ? 122 GLN C NE2 1 
ATOM   4880  N N   . ILE C 1 120 ? 3.139   21.642  -6.180   1.00 47.67  ? 123 ILE C N   1 
ATOM   4881  C CA  . ILE C 1 120 ? 2.527   22.961  -6.166   1.00 46.41  ? 123 ILE C CA  1 
ATOM   4882  C C   . ILE C 1 120 ? 2.251   23.438  -4.746   1.00 53.03  ? 123 ILE C C   1 
ATOM   4883  O O   . ILE C 1 120 ? 2.405   24.626  -4.451   1.00 68.34  ? 123 ILE C O   1 
ATOM   4884  C CB  . ILE C 1 120 ? 1.237   22.984  -7.017   1.00 55.47  ? 123 ILE C CB  1 
ATOM   4885  C CG1 . ILE C 1 120 ? 0.234   21.940  -6.520   1.00 49.42  ? 123 ILE C CG1 1 
ATOM   4886  C CG2 . ILE C 1 120 ? 1.565   22.755  -8.488   1.00 47.16  ? 123 ILE C CG2 1 
ATOM   4887  C CD1 . ILE C 1 120 ? -1.144  22.081  -7.129   1.00 47.92  ? 123 ILE C CD1 1 
ATOM   4888  N N   . ILE C 1 121 ? 1.841   22.540  -3.855   1.00 44.07  ? 124 ILE C N   1 
ATOM   4889  C CA  . ILE C 1 121 ? 1.573   22.906  -2.466   1.00 47.63  ? 124 ILE C CA  1 
ATOM   4890  C C   . ILE C 1 121 ? 2.393   22.006  -1.549   1.00 53.68  ? 124 ILE C C   1 
ATOM   4891  O O   . ILE C 1 121 ? 1.985   20.868  -1.274   1.00 57.41  ? 124 ILE C O   1 
ATOM   4892  C CB  . ILE C 1 121 ? 0.075   22.808  -2.131   1.00 45.07  ? 124 ILE C CB  1 
ATOM   4893  C CG1 . ILE C 1 121 ? -0.757  23.621  -3.122   1.00 55.49  ? 124 ILE C CG1 1 
ATOM   4894  C CG2 . ILE C 1 121 ? -0.178  23.288  -0.715   1.00 47.40  ? 124 ILE C CG2 1 
ATOM   4895  C CD1 . ILE C 1 121 ? -2.247  23.531  -2.868   1.00 43.96  ? 124 ILE C CD1 1 
ATOM   4896  N N   . PRO C 1 122 ? 3.551   22.457  -1.069   1.00 62.75  ? 125 PRO C N   1 
ATOM   4897  C CA  . PRO C 1 122 ? 4.347   21.620  -0.168   1.00 63.22  ? 125 PRO C CA  1 
ATOM   4898  C C   . PRO C 1 122 ? 3.631   21.379  1.153    1.00 59.03  ? 125 PRO C C   1 
ATOM   4899  O O   . PRO C 1 122 ? 2.762   22.144  1.578    1.00 62.72  ? 125 PRO C O   1 
ATOM   4900  C CB  . PRO C 1 122 ? 5.632   22.430  0.031    1.00 62.16  ? 125 PRO C CB  1 
ATOM   4901  C CG  . PRO C 1 122 ? 5.251   23.838  -0.298   1.00 55.00  ? 125 PRO C CG  1 
ATOM   4902  C CD  . PRO C 1 122 ? 4.214   23.735  -1.373   1.00 56.91  ? 125 PRO C CD  1 
ATOM   4903  N N   . LYS C 1 123 A 4.011   20.277  1.806    1.00 54.04  ? 125 LYS C N   1 
ATOM   4904  C CA  . LYS C 1 123 A 3.405   19.921  3.085    1.00 70.67  ? 125 LYS C CA  1 
ATOM   4905  C C   . LYS C 1 123 A 3.693   20.947  4.172    1.00 65.04  ? 125 LYS C C   1 
ATOM   4906  O O   . LYS C 1 123 A 2.987   20.972  5.186    1.00 71.00  ? 125 LYS C O   1 
ATOM   4907  C CB  . LYS C 1 123 A 3.887   18.540  3.529    1.00 71.12  ? 125 LYS C CB  1 
ATOM   4908  C CG  . LYS C 1 123 A 3.097   17.387  2.930    1.00 72.20  ? 125 LYS C CG  1 
ATOM   4909  C CD  . LYS C 1 123 A 3.787   16.060  3.188    1.00 71.76  ? 125 LYS C CD  1 
ATOM   4910  C CE  . LYS C 1 123 A 2.794   14.912  3.190    1.00 61.32  ? 125 LYS C CE  1 
ATOM   4911  N NZ  . LYS C 1 123 A 1.870   14.994  4.354    1.00 57.04  ? 125 LYS C NZ  1 
ATOM   4912  N N   . SER C 1 124 B 4.706   21.796  3.986    1.00 69.93  ? 125 SER C N   1 
ATOM   4913  C CA  . SER C 1 124 B 4.967   22.872  4.933    1.00 70.93  ? 125 SER C CA  1 
ATOM   4914  C C   . SER C 1 124 B 3.912   23.969  4.880    1.00 63.97  ? 125 SER C C   1 
ATOM   4915  O O   . SER C 1 124 B 3.904   24.839  5.757    1.00 72.19  ? 125 SER C O   1 
ATOM   4916  C CB  . SER C 1 124 B 6.354   23.469  4.679    1.00 71.67  ? 125 SER C CB  1 
ATOM   4917  O OG  . SER C 1 124 B 6.505   23.863  3.327    1.00 74.91  ? 125 SER C OG  1 
ATOM   4918  N N   . SER C 1 125 ? 3.028   23.947  3.884    1.00 64.16  ? 126 SER C N   1 
ATOM   4919  C CA  . SER C 1 125 ? 1.972   24.942  3.752    1.00 51.91  ? 126 SER C CA  1 
ATOM   4920  C C   . SER C 1 125 ? 0.788   24.684  4.677    1.00 55.60  ? 126 SER C C   1 
ATOM   4921  O O   . SER C 1 125 ? -0.198  25.426  4.608    1.00 61.17  ? 126 SER C O   1 
ATOM   4922  C CB  . SER C 1 125 ? 1.478   24.999  2.303    1.00 56.42  ? 126 SER C CB  1 
ATOM   4923  O OG  . SER C 1 125 ? 2.559   25.129  1.397    1.00 74.20  ? 126 SER C OG  1 
ATOM   4924  N N   . TRP C 1 126 ? 0.856   23.670  5.539    1.00 57.11  ? 127 TRP C N   1 
ATOM   4925  C CA  . TRP C 1 126 ? -0.237  23.329  6.451    1.00 59.50  ? 127 TRP C CA  1 
ATOM   4926  C C   . TRP C 1 126 ? 0.287   23.305  7.884    1.00 64.10  ? 127 TRP C C   1 
ATOM   4927  O O   . TRP C 1 126 ? 0.318   22.251  8.531    1.00 61.47  ? 127 TRP C O   1 
ATOM   4928  C CB  . TRP C 1 126 ? -0.857  21.980  6.082    1.00 57.99  ? 127 TRP C CB  1 
ATOM   4929  C CG  . TRP C 1 126 ? -1.071  21.776  4.608    1.00 51.67  ? 127 TRP C CG  1 
ATOM   4930  C CD1 . TRP C 1 126 ? -0.337  20.981  3.776    1.00 40.15  ? 127 TRP C CD1 1 
ATOM   4931  C CD2 . TRP C 1 126 ? -2.090  22.370  3.798    1.00 51.78  ? 127 TRP C CD2 1 
ATOM   4932  N NE1 . TRP C 1 126 ? -0.835  21.046  2.496    1.00 60.24  ? 127 TRP C NE1 1 
ATOM   4933  C CE2 . TRP C 1 126 ? -1.913  21.892  2.484    1.00 55.56  ? 127 TRP C CE2 1 
ATOM   4934  C CE3 . TRP C 1 126 ? -3.135  23.263  4.056    1.00 53.81  ? 127 TRP C CE3 1 
ATOM   4935  C CZ2 . TRP C 1 126 ? -2.741  22.275  1.433    1.00 46.37  ? 127 TRP C CZ2 1 
ATOM   4936  C CZ3 . TRP C 1 126 ? -3.955  23.641  3.010    1.00 46.62  ? 127 TRP C CZ3 1 
ATOM   4937  C CH2 . TRP C 1 126 ? -3.754  23.148  1.716    1.00 54.08  ? 127 TRP C CH2 1 
ATOM   4938  N N   . PRO C 1 127 ? 0.686   24.464  8.422    1.00 59.77  ? 128 PRO C N   1 
ATOM   4939  C CA  . PRO C 1 127 ? 1.288   24.465  9.766    1.00 54.26  ? 128 PRO C CA  1 
ATOM   4940  C C   . PRO C 1 127 ? 0.288   24.213  10.880   1.00 55.74  ? 128 PRO C C   1 
ATOM   4941  O O   . PRO C 1 127 ? 0.653   23.607  11.895   1.00 66.03  ? 128 PRO C O   1 
ATOM   4942  C CB  . PRO C 1 127 ? 1.902   25.867  9.868    1.00 47.44  ? 128 PRO C CB  1 
ATOM   4943  C CG  . PRO C 1 127 ? 1.020   26.708  9.005    1.00 64.80  ? 128 PRO C CG  1 
ATOM   4944  C CD  . PRO C 1 127 ? 0.575   25.824  7.865    1.00 59.87  ? 128 PRO C CD  1 
ATOM   4945  N N   . ASN C 1 128 ? -0.957  24.654  10.728   1.00 55.49  ? 129 ASN C N   1 
ATOM   4946  C CA  . ASN C 1 128 ? -1.971  24.510  11.763   1.00 50.42  ? 129 ASN C CA  1 
ATOM   4947  C C   . ASN C 1 128 ? -2.835  23.272  11.574   1.00 57.36  ? 129 ASN C C   1 
ATOM   4948  O O   . ASN C 1 128 ? -3.891  23.166  12.205   1.00 60.19  ? 129 ASN C O   1 
ATOM   4949  C CB  . ASN C 1 128 ? -2.853  25.760  11.805   1.00 55.21  ? 129 ASN C CB  1 
ATOM   4950  C CG  . ASN C 1 128 ? -2.043  27.035  11.916   1.00 66.80  ? 129 ASN C CG  1 
ATOM   4951  O OD1 . ASN C 1 128 ? -1.163  27.153  12.769   1.00 71.57  ? 129 ASN C OD1 1 
ATOM   4952  N ND2 . ASN C 1 128 ? -2.325  27.993  11.042   1.00 63.47  ? 129 ASN C ND2 1 
ATOM   4953  N N   . HIS C 1 129 ? -2.415  22.343  10.721   1.00 49.97  ? 130 HIS C N   1 
ATOM   4954  C CA  . HIS C 1 129 ? -3.145  21.111  10.476   1.00 58.23  ? 130 HIS C CA  1 
ATOM   4955  C C   . HIS C 1 129 ? -2.180  19.936  10.517   1.00 57.29  ? 130 HIS C C   1 
ATOM   4956  O O   . HIS C 1 129 ? -0.984  20.084  10.250   1.00 50.24  ? 130 HIS C O   1 
ATOM   4957  C CB  . HIS C 1 129 ? -3.873  21.148  9.124    1.00 51.02  ? 130 HIS C CB  1 
ATOM   4958  C CG  . HIS C 1 129 ? -4.901  22.230  9.024    1.00 48.68  ? 130 HIS C CG  1 
ATOM   4959  N ND1 . HIS C 1 129 ? -4.579  23.540  8.742    1.00 45.76  ? 130 HIS C ND1 1 
ATOM   4960  C CD2 . HIS C 1 129 ? -6.246  22.199  9.180    1.00 49.99  ? 130 HIS C CD2 1 
ATOM   4961  C CE1 . HIS C 1 129 ? -5.681  24.268  8.722    1.00 54.51  ? 130 HIS C CE1 1 
ATOM   4962  N NE2 . HIS C 1 129 ? -6.707  23.478  8.984    1.00 54.08  ? 130 HIS C NE2 1 
ATOM   4963  N N   . GLU C 1 130 ? -2.708  18.765  10.856   1.00 58.58  ? 131 GLU C N   1 
ATOM   4964  C CA  . GLU C 1 130 ? -1.894  17.560  10.888   1.00 49.78  ? 131 GLU C CA  1 
ATOM   4965  C C   . GLU C 1 130 ? -1.775  16.970  9.487    1.00 56.48  ? 131 GLU C C   1 
ATOM   4966  O O   . GLU C 1 130 ? -2.784  16.744  8.810    1.00 56.60  ? 131 GLU C O   1 
ATOM   4967  C CB  . GLU C 1 130 ? -2.492  16.534  11.846   1.00 57.19  ? 131 GLU C CB  1 
ATOM   4968  C CG  . GLU C 1 130 ? -1.680  15.267  11.928   1.00 75.16  ? 131 GLU C CG  1 
ATOM   4969  C CD  . GLU C 1 130 ? -0.289  15.501  12.480   1.00 79.01  ? 131 GLU C CD  1 
ATOM   4970  O OE1 . GLU C 1 130 ? -0.161  16.228  13.488   1.00 72.92  ? 131 GLU C OE1 1 
ATOM   4971  O OE2 . GLU C 1 130 ? 0.677   14.965  11.898   1.00 74.46  ? 131 GLU C OE2 1 
ATOM   4972  N N   . THR C 1 131 ? -0.539  16.721  9.054    1.00 56.90  ? 132 THR C N   1 
ATOM   4973  C CA  . THR C 1 131 ? -0.266  16.230  7.711    1.00 49.03  ? 132 THR C CA  1 
ATOM   4974  C C   . THR C 1 131 ? 0.242   14.795  7.687    1.00 59.00  ? 132 THR C C   1 
ATOM   4975  O O   . THR C 1 131 ? 0.600   14.298  6.613    1.00 52.13  ? 132 THR C O   1 
ATOM   4976  C CB  . THR C 1 131 ? 0.752   17.138  7.013    1.00 52.59  ? 132 THR C CB  1 
ATOM   4977  O OG1 . THR C 1 131 ? 2.010   17.054  7.693    1.00 62.52  ? 132 THR C OG1 1 
ATOM   4978  C CG2 . THR C 1 131 ? 0.274   18.581  7.021    1.00 59.20  ? 132 THR C CG2 1 
ATOM   4979  N N   . SER C 1 132 ? 0.285   14.115  8.831    1.00 47.66  ? 133 SER C N   1 
ATOM   4980  C CA  . SER C 1 132 ? 0.879   12.788  8.912    1.00 60.61  ? 133 SER C CA  1 
ATOM   4981  C C   . SER C 1 132 ? -0.080  11.717  9.415    1.00 59.29  ? 133 SER C C   1 
ATOM   4982  O O   . SER C 1 132 ? 0.320   10.552  9.519    1.00 68.07  ? 133 SER C O   1 
ATOM   4983  C CB  . SER C 1 132 ? 2.123   12.819  9.812    1.00 64.09  ? 133 SER C CB  1 
ATOM   4984  O OG  . SER C 1 132 ? 1.784   13.197  11.135   1.00 67.72  ? 133 SER C OG  1 
ATOM   4985  N N   . LEU C 1 133 A -1.323  12.070  9.737    1.00 48.61  ? 133 LEU C N   1 
ATOM   4986  C CA  . LEU C 1 133 A -2.300  11.099  10.210   1.00 60.13  ? 133 LEU C CA  1 
ATOM   4987  C C   . LEU C 1 133 A -3.236  10.604  9.115    1.00 57.26  ? 133 LEU C C   1 
ATOM   4988  O O   . LEU C 1 133 A -3.982  9.648   9.347    1.00 53.77  ? 133 LEU C O   1 
ATOM   4989  C CB  . LEU C 1 133 A -3.133  11.697  11.352   1.00 54.61  ? 133 LEU C CB  1 
ATOM   4990  C CG  . LEU C 1 133 A -2.438  11.917  12.697   1.00 76.05  ? 133 LEU C CG  1 
ATOM   4991  C CD1 . LEU C 1 133 A -3.359  12.662  13.655   1.00 62.33  ? 133 LEU C CD1 1 
ATOM   4992  C CD2 . LEU C 1 133 A -1.992  10.595  13.302   1.00 62.10  ? 133 LEU C CD2 1 
ATOM   4993  N N   . GLY C 1 134 ? -3.206  11.214  7.933    1.00 51.71  ? 134 GLY C N   1 
ATOM   4994  C CA  . GLY C 1 134 ? -4.135  10.860  6.879    1.00 49.06  ? 134 GLY C CA  1 
ATOM   4995  C C   . GLY C 1 134 ? -3.781  9.570   6.170    1.00 50.99  ? 134 GLY C C   1 
ATOM   4996  O O   . GLY C 1 134 ? -3.383  9.584   5.002    1.00 48.10  ? 134 GLY C O   1 
ATOM   4997  N N   . VAL C 1 135 ? -3.926  8.444   6.868    1.00 48.39  ? 135 VAL C N   1 
ATOM   4998  C CA  . VAL C 1 135 ? -3.614  7.137   6.313    1.00 48.53  ? 135 VAL C CA  1 
ATOM   4999  C C   . VAL C 1 135 ? -4.802  6.214   6.533    1.00 53.42  ? 135 VAL C C   1 
ATOM   5000  O O   . VAL C 1 135 ? -5.708  6.498   7.320    1.00 53.13  ? 135 VAL C O   1 
ATOM   5001  C CB  . VAL C 1 135 ? -2.336  6.524   6.926    1.00 61.81  ? 135 VAL C CB  1 
ATOM   5002  C CG1 . VAL C 1 135 ? -1.112  7.314   6.496    1.00 37.22  ? 135 VAL C CG1 1 
ATOM   5003  C CG2 . VAL C 1 135 ? -2.443  6.479   8.443    1.00 45.52  ? 135 VAL C CG2 1 
ATOM   5004  N N   . SER C 1 136 ? -4.790  5.096   5.811    1.00 60.95  ? 136 SER C N   1 
ATOM   5005  C CA  . SER C 1 136 ? -5.848  4.105   5.912    1.00 59.35  ? 136 SER C CA  1 
ATOM   5006  C C   . SER C 1 136 ? -5.275  2.733   5.600    1.00 59.14  ? 136 SER C C   1 
ATOM   5007  O O   . SER C 1 136 ? -4.386  2.594   4.755    1.00 49.70  ? 136 SER C O   1 
ATOM   5008  C CB  . SER C 1 136 ? -7.005  4.419   4.958    1.00 61.99  ? 136 SER C CB  1 
ATOM   5009  O OG  . SER C 1 136 ? -7.953  3.366   4.947    1.00 58.29  ? 136 SER C OG  1 
ATOM   5010  N N   . ALA C 1 137 ? -5.792  1.717   6.294    1.00 56.45  ? 137 ALA C N   1 
ATOM   5011  C CA  . ALA C 1 137 ? -5.422  0.343   5.984    1.00 64.40  ? 137 ALA C CA  1 
ATOM   5012  C C   . ALA C 1 137 ? -5.943  -0.104  4.626    1.00 55.31  ? 137 ALA C C   1 
ATOM   5013  O O   . ALA C 1 137 ? -5.475  -1.122  4.106    1.00 56.35  ? 137 ALA C O   1 
ATOM   5014  C CB  . ALA C 1 137 ? -5.927  -0.602  7.078    1.00 51.02  ? 137 ALA C CB  1 
ATOM   5015  N N   . ALA C 1 138 ? -6.896  0.626   4.042    1.00 56.49  ? 138 ALA C N   1 
ATOM   5016  C CA  . ALA C 1 138 ? -7.319  0.364   2.674    1.00 54.16  ? 138 ALA C CA  1 
ATOM   5017  C C   . ALA C 1 138 ? -6.247  0.720   1.656    1.00 56.82  ? 138 ALA C C   1 
ATOM   5018  O O   . ALA C 1 138 ? -6.347  0.287   0.503    1.00 58.26  ? 138 ALA C O   1 
ATOM   5019  C CB  . ALA C 1 138 ? -8.602  1.134   2.359    1.00 55.20  ? 138 ALA C CB  1 
ATOM   5020  N N   . CYS C 1 139 ? -5.226  1.475   2.054    1.00 52.35  ? 139 CYS C N   1 
ATOM   5021  C CA  . CYS C 1 139 ? -4.132  1.878   1.172    1.00 55.82  ? 139 CYS C CA  1 
ATOM   5022  C C   . CYS C 1 139 ? -2.810  1.504   1.828    1.00 54.94  ? 139 CYS C C   1 
ATOM   5023  O O   . CYS C 1 139 ? -2.043  2.378   2.246    1.00 58.86  ? 139 CYS C O   1 
ATOM   5024  C CB  . CYS C 1 139 ? -4.184  3.380   0.890    1.00 58.47  ? 139 CYS C CB  1 
ATOM   5025  S SG  . CYS C 1 139 ? -5.750  3.976   0.239    1.00 73.55  ? 139 CYS C SG  1 
ATOM   5026  N N   . PRO C 1 140 ? -2.506  0.214   1.929    1.00 51.67  ? 140 PRO C N   1 
ATOM   5027  C CA  . PRO C 1 140 ? -1.293  -0.198  2.639    1.00 56.06  ? 140 PRO C CA  1 
ATOM   5028  C C   . PRO C 1 140 ? -0.042  -0.016  1.797    1.00 49.87  ? 140 PRO C C   1 
ATOM   5029  O O   . PRO C 1 140 ? -0.064  -0.105  0.567    1.00 52.86  ? 140 PRO C O   1 
ATOM   5030  C CB  . PRO C 1 140 ? -1.547  -1.681  2.931    1.00 46.66  ? 140 PRO C CB  1 
ATOM   5031  C CG  . PRO C 1 140 ? -2.394  -2.127  1.789    1.00 59.05  ? 140 PRO C CG  1 
ATOM   5032  C CD  . PRO C 1 140 ? -3.256  -0.944  1.405    1.00 53.50  ? 140 PRO C CD  1 
ATOM   5033  N N   . TYR C 1 141 ? 1.062   0.252   2.490    1.00 49.41  ? 141 TYR C N   1 
ATOM   5034  C CA  . TYR C 1 141 ? 2.387   0.258   1.880    1.00 51.44  ? 141 TYR C CA  1 
ATOM   5035  C C   . TYR C 1 141 ? 3.359   -0.372  2.863    1.00 57.49  ? 141 TYR C C   1 
ATOM   5036  O O   . TYR C 1 141 ? 3.547   0.150   3.966    1.00 51.88  ? 141 TYR C O   1 
ATOM   5037  C CB  . TYR C 1 141 ? 2.837   1.673   1.512    1.00 49.28  ? 141 TYR C CB  1 
ATOM   5038  C CG  . TYR C 1 141 ? 4.182   1.705   0.824    1.00 62.40  ? 141 TYR C CG  1 
ATOM   5039  C CD1 . TYR C 1 141 ? 4.364   1.098   -0.413   1.00 58.96  ? 141 TYR C CD1 1 
ATOM   5040  C CD2 . TYR C 1 141 ? 5.270   2.341   1.408    1.00 61.60  ? 141 TYR C CD2 1 
ATOM   5041  C CE1 . TYR C 1 141 ? 5.591   1.122   -1.048   1.00 68.09  ? 141 TYR C CE1 1 
ATOM   5042  C CE2 . TYR C 1 141 ? 6.503   2.371   0.778    1.00 51.47  ? 141 TYR C CE2 1 
ATOM   5043  C CZ  . TYR C 1 141 ? 6.657   1.760   -0.449   1.00 71.07  ? 141 TYR C CZ  1 
ATOM   5044  O OH  . TYR C 1 141 ? 7.881   1.787   -1.079   1.00 78.57  ? 141 TYR C OH  1 
ATOM   5045  N N   . GLN C 1 142 ? 3.967   -1.490  2.460    1.00 66.79  ? 142 GLN C N   1 
ATOM   5046  C CA  . GLN C 1 142 ? 4.886   -2.244  3.315    1.00 53.10  ? 142 GLN C CA  1 
ATOM   5047  C C   . GLN C 1 142 ? 4.226   -2.621  4.640    1.00 50.03  ? 142 GLN C C   1 
ATOM   5048  O O   . GLN C 1 142 ? 4.844   -2.556  5.705    1.00 56.55  ? 142 GLN C O   1 
ATOM   5049  C CB  . GLN C 1 142 ? 6.182   -1.466  3.555    1.00 58.49  ? 142 GLN C CB  1 
ATOM   5050  C CG  . GLN C 1 142 ? 7.007   -1.225  2.300    1.00 61.18  ? 142 GLN C CG  1 
ATOM   5051  C CD  . GLN C 1 142 ? 8.204   -0.330  2.557    1.00 69.19  ? 142 GLN C CD  1 
ATOM   5052  O OE1 . GLN C 1 142 ? 8.203   0.469   3.494    1.00 69.49  ? 142 GLN C OE1 1 
ATOM   5053  N NE2 . GLN C 1 142 ? 9.236   -0.465  1.731    1.00 61.35  ? 142 GLN C NE2 1 
ATOM   5054  N N   . GLY C 1 143 ? 2.952   -3.013  4.573    1.00 48.67  ? 143 GLY C N   1 
ATOM   5055  C CA  . GLY C 1 143 ? 2.204   -3.427  5.741    1.00 52.92  ? 143 GLY C CA  1 
ATOM   5056  C C   . GLY C 1 143 ? 1.603   -2.310  6.564    1.00 57.32  ? 143 GLY C C   1 
ATOM   5057  O O   . GLY C 1 143 ? 0.623   -2.548  7.280    1.00 51.27  ? 143 GLY C O   1 
ATOM   5058  N N   . ALA C 1 144 ? 2.152   -1.097  6.491    1.00 59.98  ? 144 ALA C N   1 
ATOM   5059  C CA  . ALA C 1 144 ? 1.600   -0.006  7.278    1.00 56.24  ? 144 ALA C CA  1 
ATOM   5060  C C   . ALA C 1 144 ? 0.501   0.718   6.507    1.00 53.93  ? 144 ALA C C   1 
ATOM   5061  O O   . ALA C 1 144 ? 0.531   0.772   5.273    1.00 55.64  ? 144 ALA C O   1 
ATOM   5062  C CB  . ALA C 1 144 ? 2.696   0.987   7.652    1.00 49.20  ? 144 ALA C CB  1 
ATOM   5063  N N   . PRO C 1 145 ? -0.486  1.273   7.210    1.00 53.96  ? 145 PRO C N   1 
ATOM   5064  C CA  . PRO C 1 145 ? -1.477  2.118   6.537    1.00 53.85  ? 145 PRO C CA  1 
ATOM   5065  C C   . PRO C 1 145 ? -0.813  3.313   5.867    1.00 55.51  ? 145 PRO C C   1 
ATOM   5066  O O   . PRO C 1 145 ? 0.141   3.894   6.389    1.00 46.95  ? 145 PRO C O   1 
ATOM   5067  C CB  . PRO C 1 145 ? -2.405  2.552   7.677    1.00 48.11  ? 145 PRO C CB  1 
ATOM   5068  C CG  . PRO C 1 145 ? -2.263  1.472   8.699    1.00 52.18  ? 145 PRO C CG  1 
ATOM   5069  C CD  . PRO C 1 145 ? -0.827  1.040   8.624    1.00 46.93  ? 145 PRO C CD  1 
ATOM   5070  N N   . SER C 1 146 ? -1.330  3.673   4.699    1.00 53.24  ? 146 SER C N   1 
ATOM   5071  C CA  . SER C 1 146 ? -0.764  4.743   3.886    1.00 51.55  ? 146 SER C CA  1 
ATOM   5072  C C   . SER C 1 146 ? -1.912  5.405   3.129    1.00 52.31  ? 146 SER C C   1 
ATOM   5073  O O   . SER C 1 146 ? -3.081  5.263   3.504    1.00 54.71  ? 146 SER C O   1 
ATOM   5074  C CB  . SER C 1 146 ? 0.342   4.188   2.971    1.00 40.34  ? 146 SER C CB  1 
ATOM   5075  O OG  . SER C 1 146 ? 0.930   5.215   2.190    1.00 60.11  ? 146 SER C OG  1 
ATOM   5076  N N   . PHE C 1 147 ? -1.586  6.146   2.074    1.00 47.55  ? 147 PHE C N   1 
ATOM   5077  C CA  . PHE C 1 147 ? -2.589  6.918   1.354    1.00 44.62  ? 147 PHE C CA  1 
ATOM   5078  C C   . PHE C 1 147 ? -2.066  7.210   -0.045   1.00 42.73  ? 147 PHE C C   1 
ATOM   5079  O O   . PHE C 1 147 ? -0.908  6.931   -0.367   1.00 45.82  ? 147 PHE C O   1 
ATOM   5080  C CB  . PHE C 1 147 ? -2.922  8.210   2.112    1.00 46.88  ? 147 PHE C CB  1 
ATOM   5081  C CG  . PHE C 1 147 ? -4.173  8.894   1.641    1.00 41.76  ? 147 PHE C CG  1 
ATOM   5082  C CD1 . PHE C 1 147 ? -5.402  8.259   1.724    1.00 39.33  ? 147 PHE C CD1 1 
ATOM   5083  C CD2 . PHE C 1 147 ? -4.122  10.182  1.133    1.00 42.68  ? 147 PHE C CD2 1 
ATOM   5084  C CE1 . PHE C 1 147 ? -6.555  8.890   1.297    1.00 40.45  ? 147 PHE C CE1 1 
ATOM   5085  C CE2 . PHE C 1 147 ? -5.272  10.820  0.707    1.00 47.98  ? 147 PHE C CE2 1 
ATOM   5086  C CZ  . PHE C 1 147 ? -6.489  10.173  0.789    1.00 44.43  ? 147 PHE C CZ  1 
ATOM   5087  N N   . PHE C 1 148 ? -2.944  7.769   -0.880   1.00 50.25  ? 148 PHE C N   1 
ATOM   5088  C CA  . PHE C 1 148 ? -2.528  8.283   -2.178   1.00 37.61  ? 148 PHE C CA  1 
ATOM   5089  C C   . PHE C 1 148 ? -1.354  9.237   -1.998   1.00 47.61  ? 148 PHE C C   1 
ATOM   5090  O O   . PHE C 1 148 ? -1.363  10.088  -1.104   1.00 51.28  ? 148 PHE C O   1 
ATOM   5091  C CB  . PHE C 1 148 ? -3.687  9.008   -2.868   1.00 38.96  ? 148 PHE C CB  1 
ATOM   5092  C CG  . PHE C 1 148 ? -4.907  8.157   -3.088   1.00 46.05  ? 148 PHE C CG  1 
ATOM   5093  C CD1 . PHE C 1 148 ? -4.988  7.306   -4.179   1.00 57.12  ? 148 PHE C CD1 1 
ATOM   5094  C CD2 . PHE C 1 148 ? -5.984  8.229   -2.221   1.00 51.97  ? 148 PHE C CD2 1 
ATOM   5095  C CE1 . PHE C 1 148 ? -6.117  6.532   -4.392   1.00 47.43  ? 148 PHE C CE1 1 
ATOM   5096  C CE2 . PHE C 1 148 ? -7.113  7.457   -2.428   1.00 55.19  ? 148 PHE C CE2 1 
ATOM   5097  C CZ  . PHE C 1 148 ? -7.179  6.609   -3.515   1.00 46.67  ? 148 PHE C CZ  1 
ATOM   5098  N N   . ARG C 1 149 ? -0.334  9.079   -2.842   1.00 41.70  ? 149 ARG C N   1 
ATOM   5099  C CA  . ARG C 1 149 ? 0.911   9.812   -2.642   1.00 50.78  ? 149 ARG C CA  1 
ATOM   5100  C C   . ARG C 1 149 ? 0.829   11.261  -3.108   1.00 48.35  ? 149 ARG C C   1 
ATOM   5101  O O   . ARG C 1 149 ? 1.563   12.111  -2.594   1.00 52.84  ? 149 ARG C O   1 
ATOM   5102  C CB  . ARG C 1 149 ? 2.062   9.100   -3.357   1.00 54.54  ? 149 ARG C CB  1 
ATOM   5103  C CG  . ARG C 1 149 ? 2.362   7.701   -2.825   1.00 54.66  ? 149 ARG C CG  1 
ATOM   5104  C CD  . ARG C 1 149 ? 3.669   7.167   -3.394   1.00 56.22  ? 149 ARG C CD  1 
ATOM   5105  N NE  . ARG C 1 149 ? 4.022   5.861   -2.848   1.00 73.37  ? 149 ARG C NE  1 
ATOM   5106  C CZ  . ARG C 1 149 ? 3.997   4.725   -3.532   1.00 83.92  ? 149 ARG C CZ  1 
ATOM   5107  N NH1 . ARG C 1 149 ? 3.649   4.692   -4.809   1.00 62.48  ? 149 ARG C NH1 1 
ATOM   5108  N NH2 . ARG C 1 149 ? 4.338   3.593   -2.922   1.00 73.70  ? 149 ARG C NH2 1 
ATOM   5109  N N   . ASN C 1 150 ? -0.036  11.567  -4.072   1.00 51.94  ? 150 ASN C N   1 
ATOM   5110  C CA  . ASN C 1 150 ? -0.057  12.888  -4.688   1.00 51.41  ? 150 ASN C CA  1 
ATOM   5111  C C   . ASN C 1 150 ? -1.035  13.852  -4.026   1.00 52.26  ? 150 ASN C C   1 
ATOM   5112  O O   . ASN C 1 150 ? -1.091  15.023  -4.419   1.00 44.26  ? 150 ASN C O   1 
ATOM   5113  C CB  . ASN C 1 150 ? -0.378  12.759  -6.178   1.00 40.81  ? 150 ASN C CB  1 
ATOM   5114  C CG  . ASN C 1 150 ? 0.635   11.905  -6.911   1.00 53.33  ? 150 ASN C CG  1 
ATOM   5115  O OD1 . ASN C 1 150 ? 1.754   11.705  -6.434   1.00 42.54  ? 150 ASN C OD1 1 
ATOM   5116  N ND2 . ASN C 1 150 ? 0.252   11.397  -8.075   1.00 48.54  ? 150 ASN C ND2 1 
ATOM   5117  N N   . VAL C 1 151 ? -1.797  13.398  -3.033   1.00 48.49  ? 151 VAL C N   1 
ATOM   5118  C CA  . VAL C 1 151 ? -2.688  14.254  -2.265   1.00 43.94  ? 151 VAL C CA  1 
ATOM   5119  C C   . VAL C 1 151 ? -2.471  13.955  -0.788   1.00 52.28  ? 151 VAL C C   1 
ATOM   5120  O O   . VAL C 1 151 ? -1.959  12.898  -0.414   1.00 50.60  ? 151 VAL C O   1 
ATOM   5121  C CB  . VAL C 1 151 ? -4.170  14.056  -2.654   1.00 54.06  ? 151 VAL C CB  1 
ATOM   5122  C CG1 . VAL C 1 151 ? -4.392  14.434  -4.114   1.00 41.22  ? 151 VAL C CG1 1 
ATOM   5123  C CG2 . VAL C 1 151 ? -4.591  12.619  -2.410   1.00 47.20  ? 151 VAL C CG2 1 
ATOM   5124  N N   . VAL C 1 152 ? -2.854  14.907  0.058    1.00 46.79  ? 152 VAL C N   1 
ATOM   5125  C CA  . VAL C 1 152 ? -2.653  14.792  1.497    1.00 50.49  ? 152 VAL C CA  1 
ATOM   5126  C C   . VAL C 1 152 ? -4.004  14.888  2.195    1.00 36.87  ? 152 VAL C C   1 
ATOM   5127  O O   . VAL C 1 152 ? -4.789  15.806  1.930    1.00 51.21  ? 152 VAL C O   1 
ATOM   5128  C CB  . VAL C 1 152 ? -1.666  15.853  2.024    1.00 51.31  ? 152 VAL C CB  1 
ATOM   5129  C CG1 . VAL C 1 152 ? -2.102  17.259  1.633    1.00 60.48  ? 152 VAL C CG1 1 
ATOM   5130  C CG2 . VAL C 1 152 ? -1.506  15.728  3.531    1.00 47.04  ? 152 VAL C CG2 1 
ATOM   5131  N N   . TRP C 1 153 ? -4.274  13.926  3.072    1.00 44.10  ? 153 TRP C N   1 
ATOM   5132  C CA  . TRP C 1 153 ? -5.521  13.860  3.831    1.00 44.02  ? 153 TRP C CA  1 
ATOM   5133  C C   . TRP C 1 153 ? -5.308  14.618  5.136    1.00 48.66  ? 153 TRP C C   1 
ATOM   5134  O O   . TRP C 1 153 ? -4.719  14.094  6.083    1.00 50.29  ? 153 TRP C O   1 
ATOM   5135  C CB  . TRP C 1 153 ? -5.909  12.403  4.066    1.00 40.24  ? 153 TRP C CB  1 
ATOM   5136  C CG  . TRP C 1 153 ? -7.200  12.179  4.791    1.00 44.69  ? 153 TRP C CG  1 
ATOM   5137  C CD1 . TRP C 1 153 ? -8.065  13.127  5.256    1.00 51.39  ? 153 TRP C CD1 1 
ATOM   5138  C CD2 . TRP C 1 153 ? -7.772  10.911  5.133    1.00 48.83  ? 153 TRP C CD2 1 
ATOM   5139  N NE1 . TRP C 1 153 ? -9.141  12.526  5.867    1.00 40.27  ? 153 TRP C NE1 1 
ATOM   5140  C CE2 . TRP C 1 153 ? -8.985  11.167  5.803    1.00 46.93  ? 153 TRP C CE2 1 
ATOM   5141  C CE3 . TRP C 1 153 ? -7.376  9.583   4.937    1.00 55.44  ? 153 TRP C CE3 1 
ATOM   5142  C CZ2 . TRP C 1 153 ? -9.805  10.145  6.280    1.00 46.14  ? 153 TRP C CZ2 1 
ATOM   5143  C CZ3 . TRP C 1 153 ? -8.194  8.569   5.407    1.00 50.23  ? 153 TRP C CZ3 1 
ATOM   5144  C CH2 . TRP C 1 153 ? -9.393  8.856   6.072    1.00 50.77  ? 153 TRP C CH2 1 
ATOM   5145  N N   . LEU C 1 154 ? -5.796  15.856  5.186    1.00 42.47  ? 154 LEU C N   1 
ATOM   5146  C CA  . LEU C 1 154 ? -5.545  16.741  6.316    1.00 41.15  ? 154 LEU C CA  1 
ATOM   5147  C C   . LEU C 1 154 ? -6.465  16.419  7.488    1.00 35.90  ? 154 LEU C C   1 
ATOM   5148  O O   . LEU C 1 154 ? -7.658  16.158  7.311    1.00 43.11  ? 154 LEU C O   1 
ATOM   5149  C CB  . LEU C 1 154 ? -5.730  18.197  5.891    1.00 45.59  ? 154 LEU C CB  1 
ATOM   5150  C CG  . LEU C 1 154 ? -4.734  18.705  4.851    1.00 56.52  ? 154 LEU C CG  1 
ATOM   5151  C CD1 . LEU C 1 154 ? -5.275  19.944  4.155    1.00 44.10  ? 154 LEU C CD1 1 
ATOM   5152  C CD2 . LEU C 1 154 ? -3.393  18.996  5.508    1.00 41.11  ? 154 LEU C CD2 1 
ATOM   5153  N N   . ILE C 1 155 ? -5.900  16.464  8.696    1.00 43.16  ? 155 ILE C N   1 
ATOM   5154  C CA  . ILE C 1 155 ? -6.601  16.105  9.921    1.00 47.78  ? 155 ILE C CA  1 
ATOM   5155  C C   . ILE C 1 155 ? -6.425  17.235  10.929   1.00 49.61  ? 155 ILE C C   1 
ATOM   5156  O O   . ILE C 1 155 ? -5.481  18.025  10.856   1.00 49.10  ? 155 ILE C O   1 
ATOM   5157  C CB  . ILE C 1 155 ? -6.093  14.754  10.488   1.00 51.37  ? 155 ILE C CB  1 
ATOM   5158  C CG1 . ILE C 1 155 ? -6.309  13.642  9.465    1.00 49.84  ? 155 ILE C CG1 1 
ATOM   5159  C CG2 . ILE C 1 155 ? -6.811  14.359  11.769   1.00 58.47  ? 155 ILE C CG2 1 
ATOM   5160  C CD1 . ILE C 1 155 ? -7.765  13.422  9.127    1.00 49.29  ? 155 ILE C CD1 1 
ATOM   5161  N N   . LYS C 1 156 ? -7.370  17.318  11.865   1.00 52.42  ? 156 LYS C N   1 
ATOM   5162  C CA  . LYS C 1 156 ? -7.325  18.341  12.900   1.00 49.73  ? 156 LYS C CA  1 
ATOM   5163  C C   . LYS C 1 156 ? -6.050  18.223  13.728   1.00 57.53  ? 156 LYS C C   1 
ATOM   5164  O O   . LYS C 1 156 ? -5.441  17.155  13.835   1.00 54.14  ? 156 LYS C O   1 
ATOM   5165  C CB  . LYS C 1 156 ? -8.546  18.226  13.812   1.00 48.38  ? 156 LYS C CB  1 
ATOM   5166  C CG  . LYS C 1 156 ? -8.450  17.098  14.829   1.00 54.18  ? 156 LYS C CG  1 
ATOM   5167  C CD  . LYS C 1 156 ? -9.676  17.048  15.720   1.00 56.20  ? 156 LYS C CD  1 
ATOM   5168  C CE  . LYS C 1 156 ? -9.539  15.974  16.787   1.00 54.27  ? 156 LYS C CE  1 
ATOM   5169  N NZ  . LYS C 1 156 ? -10.829 15.745  17.497   1.00 62.13  ? 156 LYS C NZ  1 
ATOM   5170  N N   . LYS C 1 157 ? -5.646  19.348  14.313   1.00 55.71  ? 157 LYS C N   1 
ATOM   5171  C CA  . LYS C 1 157 ? -4.445  19.443  15.129   1.00 51.45  ? 157 LYS C CA  1 
ATOM   5172  C C   . LYS C 1 157 ? -4.781  20.224  16.390   1.00 60.22  ? 157 LYS C C   1 
ATOM   5173  O O   . LYS C 1 157 ? -5.415  21.282  16.313   1.00 64.13  ? 157 LYS C O   1 
ATOM   5174  C CB  . LYS C 1 157 ? -3.318  20.128  14.353   1.00 56.09  ? 157 LYS C CB  1 
ATOM   5175  C CG  . LYS C 1 157 ? -2.003  20.255  15.089   1.00 59.31  ? 157 LYS C CG  1 
ATOM   5176  C CD  . LYS C 1 157 ? -1.029  21.069  14.254   1.00 60.26  ? 157 LYS C CD  1 
ATOM   5177  C CE  . LYS C 1 157 ? 0.414   20.808  14.641   1.00 55.71  ? 157 LYS C CE  1 
ATOM   5178  N NZ  . LYS C 1 157 ? 1.347   21.380  13.630   1.00 70.33  ? 157 LYS C NZ  1 
ATOM   5179  N N   . ASN C 1 158 ? -4.356  19.703  17.544   1.00 62.80  ? 158 ASN C N   1 
ATOM   5180  C CA  . ASN C 1 158 ? -4.673  20.302  18.844   1.00 51.79  ? 158 ASN C CA  1 
ATOM   5181  C C   . ASN C 1 158 ? -6.181  20.463  19.015   1.00 56.91  ? 158 ASN C C   1 
ATOM   5182  O O   . ASN C 1 158 ? -6.668  21.471  19.533   1.00 62.39  ? 158 ASN C O   1 
ATOM   5183  C CB  . ASN C 1 158 ? -3.961  21.645  19.026   1.00 52.36  ? 158 ASN C CB  1 
ATOM   5184  C CG  . ASN C 1 158 ? -2.452  21.519  18.962   1.00 69.49  ? 158 ASN C CG  1 
ATOM   5185  O OD1 . ASN C 1 158 ? -1.878  20.541  19.440   1.00 72.36  ? 158 ASN C OD1 1 
ATOM   5186  N ND2 . ASN C 1 158 ? -1.801  22.510  18.362   1.00 74.15  ? 158 ASN C ND2 1 
ATOM   5187  N N   . ASP C 1 159 ? -6.926  19.455  18.559   1.00 68.48  ? 159 ASP C N   1 
ATOM   5188  C CA  . ASP C 1 159 ? -8.390  19.456  18.595   1.00 64.20  ? 159 ASP C CA  1 
ATOM   5189  C C   . ASP C 1 159 ? -8.972  20.681  17.893   1.00 57.78  ? 159 ASP C C   1 
ATOM   5190  O O   . ASP C 1 159 ? -10.014 21.203  18.296   1.00 64.53  ? 159 ASP C O   1 
ATOM   5191  C CB  . ASP C 1 159 ? -8.914  19.364  20.032   1.00 65.03  ? 159 ASP C CB  1 
ATOM   5192  C CG  . ASP C 1 159 ? -10.289 18.730  20.108   1.00 85.91  ? 159 ASP C CG  1 
ATOM   5193  O OD1 . ASP C 1 159 ? -10.632 17.956  19.190   1.00 74.81  ? 159 ASP C OD1 1 
ATOM   5194  O OD2 . ASP C 1 159 ? -11.027 19.010  21.077   1.00 84.32  ? 159 ASP C OD2 1 
ATOM   5195  N N   . ALA C 1 160 ? -8.305  21.148  16.839   1.00 54.09  ? 160 ALA C N   1 
ATOM   5196  C CA  . ALA C 1 160 ? -8.738  22.326  16.100   1.00 61.69  ? 160 ALA C CA  1 
ATOM   5197  C C   . ALA C 1 160 ? -8.421  22.154  14.622   1.00 50.03  ? 160 ALA C C   1 
ATOM   5198  O O   . ALA C 1 160 ? -7.374  21.611  14.262   1.00 50.26  ? 160 ALA C O   1 
ATOM   5199  C CB  . ALA C 1 160 ? -8.065  23.599  16.631   1.00 51.90  ? 160 ALA C CB  1 
ATOM   5200  N N   . TYR C 1 161 ? -9.334  22.623  13.773   1.00 50.78  ? 161 TYR C N   1 
ATOM   5201  C CA  . TYR C 1 161 ? -9.164  22.602  12.321   1.00 56.21  ? 161 TYR C CA  1 
ATOM   5202  C C   . TYR C 1 161 ? -9.436  24.011  11.814   1.00 49.96  ? 161 TYR C C   1 
ATOM   5203  O O   . TYR C 1 161 ? -10.571 24.343  11.444   1.00 45.63  ? 161 TYR C O   1 
ATOM   5204  C CB  . TYR C 1 161 ? -10.092 21.580  11.668   1.00 47.47  ? 161 TYR C CB  1 
ATOM   5205  C CG  . TYR C 1 161 ? -9.786  21.256  10.219   1.00 48.42  ? 161 TYR C CG  1 
ATOM   5206  C CD1 . TYR C 1 161 ? -10.024 22.183  9.211    1.00 46.35  ? 161 TYR C CD1 1 
ATOM   5207  C CD2 . TYR C 1 161 ? -9.289  20.010  9.855    1.00 50.44  ? 161 TYR C CD2 1 
ATOM   5208  C CE1 . TYR C 1 161 ? -9.755  21.888  7.887    1.00 44.09  ? 161 TYR C CE1 1 
ATOM   5209  C CE2 . TYR C 1 161 ? -9.020  19.705  8.531    1.00 44.49  ? 161 TYR C CE2 1 
ATOM   5210  C CZ  . TYR C 1 161 ? -9.257  20.649  7.553    1.00 48.15  ? 161 TYR C CZ  1 
ATOM   5211  O OH  . TYR C 1 161 ? -8.995  20.357  6.236    1.00 40.87  ? 161 TYR C OH  1 
ATOM   5212  N N   . PRO C 1 162 ? -8.420  24.874  11.799   1.00 51.04  ? 162 PRO C N   1 
ATOM   5213  C CA  . PRO C 1 162 ? -8.621  26.239  11.298   1.00 57.57  ? 162 PRO C CA  1 
ATOM   5214  C C   . PRO C 1 162 ? -9.023  26.229  9.831    1.00 56.65  ? 162 PRO C C   1 
ATOM   5215  O O   . PRO C 1 162 ? -8.635  25.345  9.064    1.00 52.00  ? 162 PRO C O   1 
ATOM   5216  C CB  . PRO C 1 162 ? -7.251  26.900  11.497   1.00 44.59  ? 162 PRO C CB  1 
ATOM   5217  C CG  . PRO C 1 162 ? -6.524  26.021  12.472   1.00 56.24  ? 162 PRO C CG  1 
ATOM   5218  C CD  . PRO C 1 162 ? -7.033  24.637  12.229   1.00 59.93  ? 162 PRO C CD  1 
ATOM   5219  N N   . THR C 1 163 ? -9.820  27.225  9.450    1.00 48.42  ? 163 THR C N   1 
ATOM   5220  C CA  . THR C 1 163 ? -10.272 27.328  8.069    1.00 51.29  ? 163 THR C CA  1 
ATOM   5221  C C   . THR C 1 163 ? -9.084  27.531  7.136    1.00 47.57  ? 163 THR C C   1 
ATOM   5222  O O   . THR C 1 163 ? -8.201  28.351  7.401    1.00 53.05  ? 163 THR C O   1 
ATOM   5223  C CB  . THR C 1 163 ? -11.270 28.476  7.919    1.00 45.92  ? 163 THR C CB  1 
ATOM   5224  O OG1 . THR C 1 163 ? -12.406 28.233  8.758    1.00 59.74  ? 163 THR C OG1 1 
ATOM   5225  C CG2 . THR C 1 163 ? -11.740 28.590  6.475    1.00 47.36  ? 163 THR C CG2 1 
ATOM   5226  N N   . ILE C 1 164 ? -9.067  26.772  6.046    1.00 53.57  ? 164 ILE C N   1 
ATOM   5227  C CA  . ILE C 1 164 ? -7.988  26.817  5.067    1.00 47.97  ? 164 ILE C CA  1 
ATOM   5228  C C   . ILE C 1 164 ? -8.335  27.844  3.998    1.00 48.68  ? 164 ILE C C   1 
ATOM   5229  O O   . ILE C 1 164 ? -9.453  27.852  3.476    1.00 53.26  ? 164 ILE C O   1 
ATOM   5230  C CB  . ILE C 1 164 ? -7.765  25.431  4.440    1.00 56.38  ? 164 ILE C CB  1 
ATOM   5231  C CG1 . ILE C 1 164 ? -7.236  24.446  5.482    1.00 56.51  ? 164 ILE C CG1 1 
ATOM   5232  C CG2 . ILE C 1 164 ? -6.830  25.526  3.243    1.00 40.65  ? 164 ILE C CG2 1 
ATOM   5233  C CD1 . ILE C 1 164 ? -7.130  23.027  4.966    1.00 54.56  ? 164 ILE C CD1 1 
ATOM   5234  N N   . LYS C 1 165 ? -7.382  28.720  3.683    1.00 50.91  ? 165 LYS C N   1 
ATOM   5235  C CA  . LYS C 1 165 ? -7.508  29.657  2.564    1.00 58.42  ? 165 LYS C CA  1 
ATOM   5236  C C   . LYS C 1 165 ? -6.149  29.705  1.874    1.00 46.47  ? 165 LYS C C   1 
ATOM   5237  O O   . LYS C 1 165 ? -5.219  30.342  2.376    1.00 60.78  ? 165 LYS C O   1 
ATOM   5238  C CB  . LYS C 1 165 ? -7.935  31.045  3.028    1.00 50.98  ? 165 LYS C CB  1 
ATOM   5239  C CG  . LYS C 1 165 ? -9.323  31.123  3.626    1.00 59.49  ? 165 LYS C CG  1 
ATOM   5240  C CD  . LYS C 1 165 ? -9.603  32.526  4.132    1.00 62.56  ? 165 LYS C CD  1 
ATOM   5241  C CE  . LYS C 1 165 ? -10.938 32.602  4.851    1.00 72.91  ? 165 LYS C CE  1 
ATOM   5242  N NZ  . LYS C 1 165 ? -11.128 33.917  5.523    1.00 86.93  ? 165 LYS C NZ  1 
ATOM   5243  N N   . ILE C 1 166 ? -6.029  29.031  0.735    1.00 45.84  ? 166 ILE C N   1 
ATOM   5244  C CA  . ILE C 1 166 ? -4.759  28.957  0.024    1.00 42.10  ? 166 ILE C CA  1 
ATOM   5245  C C   . ILE C 1 166 ? -5.016  29.054  -1.473   1.00 41.58  ? 166 ILE C C   1 
ATOM   5246  O O   . ILE C 1 166 ? -5.977  28.478  -1.996   1.00 46.91  ? 166 ILE C O   1 
ATOM   5247  C CB  . ILE C 1 166 ? -3.980  27.672  0.385    1.00 43.49  ? 166 ILE C CB  1 
ATOM   5248  C CG1 . ILE C 1 166 ? -2.592  27.690  -0.256   1.00 43.30  ? 166 ILE C CG1 1 
ATOM   5249  C CG2 . ILE C 1 166 ? -4.760  26.424  -0.011   1.00 44.09  ? 166 ILE C CG2 1 
ATOM   5250  C CD1 . ILE C 1 166 ? -1.585  26.802  0.447    1.00 49.98  ? 166 ILE C CD1 1 
ATOM   5251  N N   . SER C 1 167 ? -4.162  29.804  -2.158   1.00 45.61  ? 167 SER C N   1 
ATOM   5252  C CA  . SER C 1 167 ? -4.222  29.951  -3.600   1.00 45.70  ? 167 SER C CA  1 
ATOM   5253  C C   . SER C 1 167 ? -2.890  29.531  -4.200   1.00 47.83  ? 167 SER C C   1 
ATOM   5254  O O   . SER C 1 167 ? -1.836  29.672  -3.573   1.00 54.95  ? 167 SER C O   1 
ATOM   5255  C CB  . SER C 1 167 ? -4.542  31.396  -4.005   1.00 44.95  ? 167 SER C CB  1 
ATOM   5256  O OG  . SER C 1 167 ? -5.771  31.829  -3.448   1.00 53.39  ? 167 SER C OG  1 
ATOM   5257  N N   . TYR C 1 168 ? -2.946  28.995  -5.414   1.00 43.97  ? 168 TYR C N   1 
ATOM   5258  C CA  . TYR C 1 168 ? -1.749  28.679  -6.177   1.00 49.38  ? 168 TYR C CA  1 
ATOM   5259  C C   . TYR C 1 168 ? -1.887  29.276  -7.566   1.00 45.22  ? 168 TYR C C   1 
ATOM   5260  O O   . TYR C 1 168 ? -2.874  29.017  -8.260   1.00 46.79  ? 168 TYR C O   1 
ATOM   5261  C CB  . TYR C 1 168 ? -1.509  27.169  -6.277   1.00 45.68  ? 168 TYR C CB  1 
ATOM   5262  C CG  . TYR C 1 168 ? -0.450  26.817  -7.299   1.00 53.49  ? 168 TYR C CG  1 
ATOM   5263  C CD1 . TYR C 1 168 ? 0.899   26.830  -6.966   1.00 39.18  ? 168 TYR C CD1 1 
ATOM   5264  C CD2 . TYR C 1 168 ? -0.799  26.488  -8.604   1.00 43.64  ? 168 TYR C CD2 1 
ATOM   5265  C CE1 . TYR C 1 168 ? 1.869   26.521  -7.901   1.00 50.42  ? 168 TYR C CE1 1 
ATOM   5266  C CE2 . TYR C 1 168 ? 0.162   26.186  -9.545   1.00 43.79  ? 168 TYR C CE2 1 
ATOM   5267  C CZ  . TYR C 1 168 ? 1.493   26.199  -9.191   1.00 54.19  ? 168 TYR C CZ  1 
ATOM   5268  O OH  . TYR C 1 168 ? 2.448   25.889  -10.131  1.00 59.96  ? 168 TYR C OH  1 
ATOM   5269  N N   . ASN C 1 169 ? -0.889  30.055  -7.969   1.00 52.34  ? 169 ASN C N   1 
ATOM   5270  C CA  . ASN C 1 169 ? -0.848  30.700  -9.274   1.00 51.15  ? 169 ASN C CA  1 
ATOM   5271  C C   . ASN C 1 169 ? 0.003   29.850  -10.208  1.00 48.28  ? 169 ASN C C   1 
ATOM   5272  O O   . ASN C 1 169 ? 1.115   29.450  -9.848   1.00 54.29  ? 169 ASN C O   1 
ATOM   5273  C CB  . ASN C 1 169 ? -0.283  32.118  -9.137   1.00 43.75  ? 169 ASN C CB  1 
ATOM   5274  C CG  . ASN C 1 169 ? -0.297  32.904  -10.438  1.00 38.22  ? 169 ASN C CG  1 
ATOM   5275  O OD1 . ASN C 1 169 ? -0.023  32.371  -11.514  1.00 50.40  ? 169 ASN C OD1 1 
ATOM   5276  N ND2 . ASN C 1 169 ? -0.610  34.195  -10.339  1.00 51.67  ? 169 ASN C ND2 1 
ATOM   5277  N N   . ASN C 1 170 ? -0.520  29.570  -11.401  1.00 44.86  ? 170 ASN C N   1 
ATOM   5278  C CA  . ASN C 1 170 ? 0.179   28.724  -12.370  1.00 52.40  ? 170 ASN C CA  1 
ATOM   5279  C C   . ASN C 1 170 ? 1.184   29.579  -13.130  1.00 51.83  ? 170 ASN C C   1 
ATOM   5280  O O   . ASN C 1 170 ? 0.883   30.157  -14.176  1.00 51.39  ? 170 ASN C O   1 
ATOM   5281  C CB  . ASN C 1 170 ? -0.806  28.052  -13.318  1.00 45.57  ? 170 ASN C CB  1 
ATOM   5282  C CG  . ASN C 1 170 ? -0.121  27.125  -14.306  1.00 50.87  ? 170 ASN C CG  1 
ATOM   5283  O OD1 . ASN C 1 170 ? 1.026   26.729  -14.106  1.00 46.89  ? 170 ASN C OD1 1 
ATOM   5284  N ND2 . ASN C 1 170 ? -0.824  26.773  -15.377  1.00 52.40  ? 170 ASN C ND2 1 
ATOM   5285  N N   . THR C 1 171 ? 2.404   29.646  -12.603  1.00 54.07  ? 171 THR C N   1 
ATOM   5286  C CA  . THR C 1 171 ? 3.475   30.406  -13.234  1.00 52.28  ? 171 THR C CA  1 
ATOM   5287  C C   . THR C 1 171 ? 4.201   29.621  -14.318  1.00 58.23  ? 171 THR C C   1 
ATOM   5288  O O   . THR C 1 171 ? 5.104   30.172  -14.957  1.00 67.19  ? 171 THR C O   1 
ATOM   5289  C CB  . THR C 1 171 ? 4.477   30.878  -12.178  1.00 56.00  ? 171 THR C CB  1 
ATOM   5290  O OG1 . THR C 1 171 ? 4.790   29.793  -11.295  1.00 69.40  ? 171 THR C OG1 1 
ATOM   5291  C CG2 . THR C 1 171 ? 3.895   32.032  -11.373  1.00 57.41  ? 171 THR C CG2 1 
ATOM   5292  N N   . ASN C 1 172 ? 3.843   28.359  -14.536  1.00 56.85  ? 172 ASN C N   1 
ATOM   5293  C CA  . ASN C 1 172 ? 4.394   27.597  -15.643  1.00 59.26  ? 172 ASN C CA  1 
ATOM   5294  C C   . ASN C 1 172 ? 3.746   28.034  -16.955  1.00 54.82  ? 172 ASN C C   1 
ATOM   5295  O O   . ASN C 1 172 ? 2.719   28.718  -16.978  1.00 62.98  ? 172 ASN C O   1 
ATOM   5296  C CB  . ASN C 1 172 ? 4.191   26.099  -15.420  1.00 52.84  ? 172 ASN C CB  1 
ATOM   5297  C CG  . ASN C 1 172 ? 4.600   25.655  -14.030  1.00 46.89  ? 172 ASN C CG  1 
ATOM   5298  O OD1 . ASN C 1 172 ? 3.770   25.572  -13.125  1.00 67.09  ? 172 ASN C OD1 1 
ATOM   5299  N ND2 . ASN C 1 172 ? 5.884   25.370  -13.852  1.00 61.47  ? 172 ASN C ND2 1 
ATOM   5300  N N   . ARG C 1 173 ? 4.363   27.634  -18.064  1.00 62.67  ? 173 ARG C N   1 
ATOM   5301  C CA  . ARG C 1 173 ? 3.870   27.982  -19.390  1.00 69.78  ? 173 ARG C CA  1 
ATOM   5302  C C   . ARG C 1 173 ? 3.010   26.880  -19.999  1.00 62.09  ? 173 ARG C C   1 
ATOM   5303  O O   . ARG C 1 173 ? 2.601   26.990  -21.159  1.00 67.47  ? 173 ARG C O   1 
ATOM   5304  C CB  . ARG C 1 173 ? 5.050   28.333  -20.306  1.00 78.34  ? 173 ARG C CB  1 
ATOM   5305  C CG  . ARG C 1 173 ? 4.734   29.206  -21.538  1.00 92.82  ? 173 ARG C CG  1 
ATOM   5306  C CD  . ARG C 1 173 ? 3.790   30.394  -21.268  1.00 88.84  ? 173 ARG C CD  1 
ATOM   5307  N NE  . ARG C 1 173 ? 3.881   30.946  -19.920  1.00 100.20 ? 173 ARG C NE  1 
ATOM   5308  C CZ  . ARG C 1 173 ? 3.047   31.849  -19.422  1.00 101.12 ? 173 ARG C CZ  1 
ATOM   5309  N NH1 . ARG C 1 173 ? 2.098   32.396  -20.164  1.00 91.32  ? 173 ARG C NH1 1 
ATOM   5310  N NH2 . ARG C 1 173 ? 3.163   32.207  -18.146  1.00 90.05  ? 173 ARG C NH2 1 
ATOM   5311  N N   . GLU C 1 174 ? 2.713   25.834  -19.235  1.00 56.65  ? 174 GLU C N   1 
ATOM   5312  C CA  . GLU C 1 174 ? 1.833   24.761  -19.666  1.00 61.56  ? 174 GLU C CA  1 
ATOM   5313  C C   . GLU C 1 174 ? 0.641   24.663  -18.722  1.00 58.90  ? 174 GLU C C   1 
ATOM   5314  O O   . GLU C 1 174 ? 0.683   25.138  -17.583  1.00 52.37  ? 174 GLU C O   1 
ATOM   5315  C CB  . GLU C 1 174 ? 2.579   23.421  -19.716  1.00 57.75  ? 174 GLU C CB  1 
ATOM   5316  C CG  . GLU C 1 174 ? 3.653   23.354  -20.789  1.00 62.76  ? 174 GLU C CG  1 
ATOM   5317  C CD  . GLU C 1 174 ? 5.016   22.995  -20.232  1.00 84.63  ? 174 GLU C CD  1 
ATOM   5318  O OE1 . GLU C 1 174 ? 5.355   23.479  -19.132  1.00 81.93  ? 174 GLU C OE1 1 
ATOM   5319  O OE2 . GLU C 1 174 ? 5.747   22.227  -20.894  1.00 86.91  ? 174 GLU C OE2 1 
ATOM   5320  N N   . ASP C 1 175 ? -0.432  24.051  -19.216  1.00 49.96  ? 175 ASP C N   1 
ATOM   5321  C CA  . ASP C 1 175 ? -1.594  23.786  -18.379  1.00 48.38  ? 175 ASP C CA  1 
ATOM   5322  C C   . ASP C 1 175 ? -1.222  22.843  -17.242  1.00 50.28  ? 175 ASP C C   1 
ATOM   5323  O O   . ASP C 1 175 ? -0.360  21.972  -17.383  1.00 52.21  ? 175 ASP C O   1 
ATOM   5324  C CB  . ASP C 1 175 ? -2.726  23.166  -19.202  1.00 52.86  ? 175 ASP C CB  1 
ATOM   5325  C CG  . ASP C 1 175 ? -3.398  24.161  -20.127  1.00 58.57  ? 175 ASP C CG  1 
ATOM   5326  O OD1 . ASP C 1 175 ? -3.525  25.344  -19.749  1.00 67.39  ? 175 ASP C OD1 1 
ATOM   5327  O OD2 . ASP C 1 175 ? -3.812  23.752  -21.233  1.00 67.30  ? 175 ASP C OD2 1 
ATOM   5328  N N   . LEU C 1 176 ? -1.880  23.026  -16.102  1.00 40.85  ? 176 LEU C N   1 
ATOM   5329  C CA  . LEU C 1 176 ? -1.762  22.118  -14.970  1.00 41.05  ? 176 LEU C CA  1 
ATOM   5330  C C   . LEU C 1 176 ? -3.040  21.304  -14.844  1.00 48.41  ? 176 LEU C C   1 
ATOM   5331  O O   . LEU C 1 176 ? -4.142  21.859  -14.908  1.00 40.62  ? 176 LEU C O   1 
ATOM   5332  C CB  . LEU C 1 176 ? -1.507  22.872  -13.664  1.00 49.50  ? 176 LEU C CB  1 
ATOM   5333  C CG  . LEU C 1 176 ? -0.141  23.515  -13.443  1.00 52.50  ? 176 LEU C CG  1 
ATOM   5334  C CD1 . LEU C 1 176 ? 0.069   23.788  -11.968  1.00 51.07  ? 176 LEU C CD1 1 
ATOM   5335  C CD2 . LEU C 1 176 ? 0.957   22.626  -13.976  1.00 57.51  ? 176 LEU C CD2 1 
ATOM   5336  N N   . LEU C 1 177 ? -2.887  19.994  -14.683  1.00 48.45  ? 177 LEU C N   1 
ATOM   5337  C CA  . LEU C 1 177 ? -3.979  19.130  -14.259  1.00 46.36  ? 177 LEU C CA  1 
ATOM   5338  C C   . LEU C 1 177 ? -3.883  18.969  -12.747  1.00 44.00  ? 177 LEU C C   1 
ATOM   5339  O O   . LEU C 1 177 ? -2.861  18.498  -12.235  1.00 47.31  ? 177 LEU C O   1 
ATOM   5340  C CB  . LEU C 1 177 ? -3.908  17.775  -14.961  1.00 42.47  ? 177 LEU C CB  1 
ATOM   5341  C CG  . LEU C 1 177 ? -4.812  16.652  -14.442  1.00 43.19  ? 177 LEU C CG  1 
ATOM   5342  C CD1 . LEU C 1 177 ? -6.280  16.966  -14.687  1.00 40.50  ? 177 LEU C CD1 1 
ATOM   5343  C CD2 . LEU C 1 177 ? -4.435  15.322  -15.075  1.00 41.91  ? 177 LEU C CD2 1 
ATOM   5344  N N   . ILE C 1 178 ? -4.928  19.383  -12.033  1.00 44.34  ? 178 ILE C N   1 
ATOM   5345  C CA  . ILE C 1 178 ? -4.930  19.406  -10.575  1.00 41.54  ? 178 ILE C CA  1 
ATOM   5346  C C   . ILE C 1 178 ? -6.088  18.559  -10.072  1.00 40.04  ? 178 ILE C C   1 
ATOM   5347  O O   . ILE C 1 178 ? -7.202  18.640  -10.600  1.00 47.60  ? 178 ILE C O   1 
ATOM   5348  C CB  . ILE C 1 178 ? -5.035  20.842  -10.024  1.00 44.95  ? 178 ILE C CB  1 
ATOM   5349  C CG1 . ILE C 1 178 ? -3.967  21.738  -10.648  1.00 41.58  ? 178 ILE C CG1 1 
ATOM   5350  C CG2 . ILE C 1 178 ? -4.906  20.838  -8.511   1.00 32.31  ? 178 ILE C CG2 1 
ATOM   5351  C CD1 . ILE C 1 178 ? -3.992  23.158  -10.127  1.00 40.05  ? 178 ILE C CD1 1 
ATOM   5352  N N   . LEU C 1 179 ? -5.828  17.756  -9.042   1.00 40.85  ? 179 LEU C N   1 
ATOM   5353  C CA  . LEU C 1 179 ? -6.843  16.895  -8.454   1.00 33.61  ? 179 LEU C CA  1 
ATOM   5354  C C   . LEU C 1 179 ? -6.937  17.143  -6.957   1.00 41.59  ? 179 LEU C C   1 
ATOM   5355  O O   . LEU C 1 179 ? -5.926  17.379  -6.289   1.00 49.22  ? 179 LEU C O   1 
ATOM   5356  C CB  . LEU C 1 179 ? -6.549  15.411  -8.720   1.00 42.68  ? 179 LEU C CB  1 
ATOM   5357  C CG  . LEU C 1 179 ? -6.632  14.953  -10.182  1.00 53.63  ? 179 LEU C CG  1 
ATOM   5358  C CD1 . LEU C 1 179 ? -5.304  15.149  -10.900  1.00 47.84  ? 179 LEU C CD1 1 
ATOM   5359  C CD2 . LEU C 1 179 ? -7.090  13.505  -10.277  1.00 51.56  ? 179 LEU C CD2 1 
ATOM   5360  N N   . TRP C 1 180 ? -8.162  17.089  -6.440   1.00 42.47  ? 180 TRP C N   1 
ATOM   5361  C CA  . TRP C 1 180 ? -8.428  17.245  -5.017   1.00 42.00  ? 180 TRP C CA  1 
ATOM   5362  C C   . TRP C 1 180 ? -9.642  16.394  -4.679   1.00 42.49  ? 180 TRP C C   1 
ATOM   5363  O O   . TRP C 1 180 ? -10.360 15.926  -5.565   1.00 37.42  ? 180 TRP C O   1 
ATOM   5364  C CB  . TRP C 1 180 ? -8.663  18.710  -4.640   1.00 37.08  ? 180 TRP C CB  1 
ATOM   5365  C CG  . TRP C 1 180 ? -9.893  19.278  -5.278   1.00 39.31  ? 180 TRP C CG  1 
ATOM   5366  C CD1 . TRP C 1 180 ? -11.136 19.370  -4.723   1.00 39.75  ? 180 TRP C CD1 1 
ATOM   5367  C CD2 . TRP C 1 180 ? -10.002 19.815  -6.599   1.00 40.53  ? 180 TRP C CD2 1 
ATOM   5368  N NE1 . TRP C 1 180 ? -12.012 19.937  -5.617   1.00 39.83  ? 180 TRP C NE1 1 
ATOM   5369  C CE2 . TRP C 1 180 ? -11.341 20.220  -6.777   1.00 42.87  ? 180 TRP C CE2 1 
ATOM   5370  C CE3 . TRP C 1 180 ? -9.097  19.997  -7.649   1.00 34.16  ? 180 TRP C CE3 1 
ATOM   5371  C CZ2 . TRP C 1 180 ? -11.796 20.796  -7.961   1.00 38.16  ? 180 TRP C CZ2 1 
ATOM   5372  C CZ3 . TRP C 1 180 ? -9.551  20.569  -8.825   1.00 40.13  ? 180 TRP C CZ3 1 
ATOM   5373  C CH2 . TRP C 1 180 ? -10.888 20.961  -8.971   1.00 37.75  ? 180 TRP C CH2 1 
ATOM   5374  N N   . GLY C 1 181 ? -9.874  16.198  -3.380   1.00 45.05  ? 181 GLY C N   1 
ATOM   5375  C CA  . GLY C 1 181 ? -10.927 15.310  -2.942   1.00 41.91  ? 181 GLY C CA  1 
ATOM   5376  C C   . GLY C 1 181 ? -11.644 15.825  -1.711   1.00 42.71  ? 181 GLY C C   1 
ATOM   5377  O O   . GLY C 1 181 ? -11.200 16.760  -1.039   1.00 44.34  ? 181 GLY C O   1 
ATOM   5378  N N   . ILE C 1 182 ? -12.782 15.192  -1.439   1.00 42.82  ? 182 ILE C N   1 
ATOM   5379  C CA  . ILE C 1 182 ? -13.562 15.411  -0.229   1.00 40.94  ? 182 ILE C CA  1 
ATOM   5380  C C   . ILE C 1 182 ? -13.810 14.053  0.410    1.00 42.69  ? 182 ILE C C   1 
ATOM   5381  O O   . ILE C 1 182 ? -14.090 13.071  -0.288   1.00 42.86  ? 182 ILE C O   1 
ATOM   5382  C CB  . ILE C 1 182 ? -14.892 16.141  -0.521   1.00 42.33  ? 182 ILE C CB  1 
ATOM   5383  C CG1 . ILE C 1 182 ? -15.683 16.362  0.770    1.00 49.47  ? 182 ILE C CG1 1 
ATOM   5384  C CG2 . ILE C 1 182 ? -15.723 15.379  -1.549   1.00 47.17  ? 182 ILE C CG2 1 
ATOM   5385  C CD1 . ILE C 1 182 ? -16.805 17.368  0.632    1.00 44.10  ? 182 ILE C CD1 1 
ATOM   5386  N N   . HIS C 1 183 ? -13.676 13.984  1.729    1.00 43.01  ? 183 HIS C N   1 
ATOM   5387  C CA  . HIS C 1 183 ? -13.891 12.743  2.459    1.00 44.45  ? 183 HIS C CA  1 
ATOM   5388  C C   . HIS C 1 183 ? -15.250 12.779  3.142    1.00 46.09  ? 183 HIS C C   1 
ATOM   5389  O O   . HIS C 1 183 ? -15.553 13.719  3.885    1.00 46.11  ? 183 HIS C O   1 
ATOM   5390  C CB  . HIS C 1 183 ? -12.789 12.510  3.493    1.00 37.53  ? 183 HIS C CB  1 
ATOM   5391  C CG  . HIS C 1 183 ? -13.094 11.399  4.445    1.00 46.37  ? 183 HIS C CG  1 
ATOM   5392  N ND1 . HIS C 1 183 ? -13.378 11.616  5.775    1.00 48.08  ? 183 HIS C ND1 1 
ATOM   5393  C CD2 . HIS C 1 183 ? -13.186 10.062  4.253    1.00 46.67  ? 183 HIS C CD2 1 
ATOM   5394  C CE1 . HIS C 1 183 ? -13.620 10.460  6.366    1.00 50.97  ? 183 HIS C CE1 1 
ATOM   5395  N NE2 . HIS C 1 183 ? -13.509 9.501   5.465    1.00 51.35  ? 183 HIS C NE2 1 
ATOM   5396  N N   . HIS C 1 184 ? -16.061 11.754  2.892    1.00 51.57  ? 184 HIS C N   1 
ATOM   5397  C CA  . HIS C 1 184 ? -17.379 11.637  3.501    1.00 48.81  ? 184 HIS C CA  1 
ATOM   5398  C C   . HIS C 1 184 ? -17.270 10.798  4.770    1.00 52.75  ? 184 HIS C C   1 
ATOM   5399  O O   . HIS C 1 184 ? -16.889 9.623   4.714    1.00 56.46  ? 184 HIS C O   1 
ATOM   5400  C CB  . HIS C 1 184 ? -18.371 11.013  2.522    1.00 50.79  ? 184 HIS C CB  1 
ATOM   5401  C CG  . HIS C 1 184 ? -18.489 11.752  1.225    1.00 46.53  ? 184 HIS C CG  1 
ATOM   5402  N ND1 . HIS C 1 184 ? -18.979 13.037  1.142    1.00 47.69  ? 184 HIS C ND1 1 
ATOM   5403  C CD2 . HIS C 1 184 ? -18.188 11.383  -0.042   1.00 47.97  ? 184 HIS C CD2 1 
ATOM   5404  C CE1 . HIS C 1 184 ? -18.971 13.430  -0.119   1.00 46.24  ? 184 HIS C CE1 1 
ATOM   5405  N NE2 . HIS C 1 184 ? -18.497 12.444  -0.859   1.00 49.31  ? 184 HIS C NE2 1 
ATOM   5406  N N   . SER C 1 185 ? -17.610 11.400  5.907    1.00 58.82  ? 185 SER C N   1 
ATOM   5407  C CA  . SER C 1 185 ? -17.502 10.725  7.191    1.00 55.53  ? 185 SER C CA  1 
ATOM   5408  C C   . SER C 1 185 ? -18.591 9.668   7.350    1.00 51.69  ? 185 SER C C   1 
ATOM   5409  O O   . SER C 1 185 ? -19.586 9.639   6.619    1.00 53.34  ? 185 SER C O   1 
ATOM   5410  C CB  . SER C 1 185 ? -17.591 11.734  8.337    1.00 48.24  ? 185 SER C CB  1 
ATOM   5411  O OG  . SER C 1 185 ? -16.472 12.600  8.343    1.00 70.57  ? 185 SER C OG  1 
ATOM   5412  N N   . ASN C 1 186 ? -18.386 8.785   8.330    1.00 56.17  ? 186 ASN C N   1 
ATOM   5413  C CA  . ASN C 1 186 ? -19.339 7.724   8.639    1.00 56.26  ? 186 ASN C CA  1 
ATOM   5414  C C   . ASN C 1 186 ? -20.440 8.181   9.590    1.00 55.01  ? 186 ASN C C   1 
ATOM   5415  O O   . ASN C 1 186 ? -21.598 7.779   9.430    1.00 55.78  ? 186 ASN C O   1 
ATOM   5416  C CB  . ASN C 1 186 ? -18.605 6.519   9.234    1.00 50.08  ? 186 ASN C CB  1 
ATOM   5417  C CG  . ASN C 1 186 ? -17.778 5.778   8.205    1.00 54.36  ? 186 ASN C CG  1 
ATOM   5418  O OD1 . ASN C 1 186 ? -18.224 5.559   7.079    1.00 71.13  ? 186 ASN C OD1 1 
ATOM   5419  N ND2 . ASN C 1 186 ? -16.564 5.393   8.582    1.00 47.11  ? 186 ASN C ND2 1 
ATOM   5420  N N   . ASN C 1 187 ? -20.107 9.008   10.577   1.00 56.17  ? 187 ASN C N   1 
ATOM   5421  C CA  . ASN C 1 187 ? -21.083 9.464   11.559   1.00 61.03  ? 187 ASN C CA  1 
ATOM   5422  C C   . ASN C 1 187 ? -20.600 10.784  12.149   1.00 58.02  ? 187 ASN C C   1 
ATOM   5423  O O   . ASN C 1 187 ? -19.500 11.257  11.848   1.00 59.78  ? 187 ASN C O   1 
ATOM   5424  C CB  . ASN C 1 187 ? -21.320 8.403   12.640   1.00 52.66  ? 187 ASN C CB  1 
ATOM   5425  C CG  . ASN C 1 187 ? -20.045 7.997   13.360   1.00 56.68  ? 187 ASN C CG  1 
ATOM   5426  O OD1 . ASN C 1 187 ? -19.232 8.838   13.743   1.00 58.97  ? 187 ASN C OD1 1 
ATOM   5427  N ND2 . ASN C 1 187 ? -19.867 6.695   13.548   1.00 75.17  ? 187 ASN C ND2 1 
ATOM   5428  N N   . ALA C 1 188 ? -21.440 11.375  13.005   1.00 51.16  ? 188 ALA C N   1 
ATOM   5429  C CA  . ALA C 1 188 ? -21.113 12.669  13.597   1.00 59.48  ? 188 ALA C CA  1 
ATOM   5430  C C   . ALA C 1 188 ? -19.853 12.593  14.452   1.00 53.64  ? 188 ALA C C   1 
ATOM   5431  O O   . ALA C 1 188 ? -19.002 13.489  14.395   1.00 62.95  ? 188 ALA C O   1 
ATOM   5432  C CB  . ALA C 1 188 ? -22.291 13.180  14.426   1.00 52.63  ? 188 ALA C CB  1 
ATOM   5433  N N   . GLU C 1 189 ? -19.718 11.535  15.256   1.00 61.37  ? 189 GLU C N   1 
ATOM   5434  C CA  . GLU C 1 189 ? -18.554 11.414  16.128   1.00 63.13  ? 189 GLU C CA  1 
ATOM   5435  C C   . GLU C 1 189 ? -17.267 11.271  15.326   1.00 57.27  ? 189 GLU C C   1 
ATOM   5436  O O   . GLU C 1 189 ? -16.251 11.893  15.658   1.00 59.27  ? 189 GLU C O   1 
ATOM   5437  C CB  . GLU C 1 189 ? -18.727 10.230  17.078   1.00 63.80  ? 189 GLU C CB  1 
ATOM   5438  C CG  . GLU C 1 189 ? -17.528 9.990   17.980   1.00 68.73  ? 189 GLU C CG  1 
ATOM   5439  C CD  . GLU C 1 189 ? -17.746 8.842   18.942   1.00 101.01 ? 189 GLU C CD  1 
ATOM   5440  O OE1 . GLU C 1 189 ? -18.884 8.329   19.004   1.00 103.82 ? 189 GLU C OE1 1 
ATOM   5441  O OE2 . GLU C 1 189 ? -16.781 8.453   19.635   1.00 106.78 ? 189 GLU C OE2 1 
ATOM   5442  N N   . GLU C 1 190 ? -17.287 10.456  14.269   1.00 51.26  ? 190 GLU C N   1 
ATOM   5443  C CA  . GLU C 1 190 ? -16.112 10.328  13.415   1.00 49.13  ? 190 GLU C CA  1 
ATOM   5444  C C   . GLU C 1 190 ? -15.770 11.649  12.737   1.00 48.99  ? 190 GLU C C   1 
ATOM   5445  O O   . GLU C 1 190 ? -14.589 11.960  12.548   1.00 55.55  ? 190 GLU C O   1 
ATOM   5446  C CB  . GLU C 1 190 ? -16.341 9.231   12.377   1.00 43.14  ? 190 GLU C CB  1 
ATOM   5447  C CG  . GLU C 1 190 ? -15.184 9.011   11.418   1.00 55.58  ? 190 GLU C CG  1 
ATOM   5448  C CD  . GLU C 1 190 ? -15.455 7.889   10.436   1.00 67.37  ? 190 GLU C CD  1 
ATOM   5449  O OE1 . GLU C 1 190 ? -15.546 6.721   10.873   1.00 61.86  ? 190 GLU C OE1 1 
ATOM   5450  O OE2 . GLU C 1 190 ? -15.600 8.180   9.230    1.00 68.18  ? 190 GLU C OE2 1 
ATOM   5451  N N   . GLN C 1 191 ? -16.786 12.436  12.376   1.00 47.36  ? 191 GLN C N   1 
ATOM   5452  C CA  . GLN C 1 191 ? -16.548 13.749  11.786   1.00 45.28  ? 191 GLN C CA  1 
ATOM   5453  C C   . GLN C 1 191 ? -15.797 14.661  12.752   1.00 62.05  ? 191 GLN C C   1 
ATOM   5454  O O   . GLN C 1 191 ? -14.797 15.287  12.382   1.00 49.88  ? 191 GLN C O   1 
ATOM   5455  C CB  . GLN C 1 191 ? -17.880 14.375  11.371   1.00 42.61  ? 191 GLN C CB  1 
ATOM   5456  C CG  . GLN C 1 191 ? -17.788 15.829  10.925   1.00 47.96  ? 191 GLN C CG  1 
ATOM   5457  C CD  . GLN C 1 191 ? -17.137 15.994  9.567    1.00 51.36  ? 191 GLN C CD  1 
ATOM   5458  O OE1 . GLN C 1 191 ? -17.137 15.076  8.748    1.00 51.74  ? 191 GLN C OE1 1 
ATOM   5459  N NE2 . GLN C 1 191 ? -16.576 17.173  9.323    1.00 40.62  ? 191 GLN C NE2 1 
ATOM   5460  N N   . THR C 1 192 ? -16.262 14.745  14.003   1.00 56.17  ? 192 THR C N   1 
ATOM   5461  C CA  . THR C 1 192 ? -15.592 15.608  14.972   1.00 55.22  ? 192 THR C CA  1 
ATOM   5462  C C   . THR C 1 192 ? -14.273 15.010  15.446   1.00 51.17  ? 192 THR C C   1 
ATOM   5463  O O   . THR C 1 192 ? -13.367 15.752  15.843   1.00 53.67  ? 192 THR C O   1 
ATOM   5464  C CB  . THR C 1 192 ? -16.505 15.886  16.167   1.00 52.30  ? 192 THR C CB  1 
ATOM   5465  O OG1 . THR C 1 192 ? -16.818 14.656  16.832   1.00 59.65  ? 192 THR C OG1 1 
ATOM   5466  C CG2 . THR C 1 192 ? -17.792 16.553  15.709   1.00 56.78  ? 192 THR C CG2 1 
ATOM   5467  N N   . ASN C 1 193 ? -14.144 13.680  15.419   1.00 49.60  ? 193 ASN C N   1 
ATOM   5468  C CA  . ASN C 1 193 ? -12.873 13.058  15.777   1.00 48.17  ? 193 ASN C CA  1 
ATOM   5469  C C   . ASN C 1 193 ? -11.779 13.391  14.771   1.00 50.13  ? 193 ASN C C   1 
ATOM   5470  O O   . ASN C 1 193 ? -10.608 13.502  15.147   1.00 62.02  ? 193 ASN C O   1 
ATOM   5471  C CB  . ASN C 1 193 ? -13.030 11.542  15.890   1.00 57.46  ? 193 ASN C CB  1 
ATOM   5472  C CG  . ASN C 1 193 ? -13.560 11.109  17.242   1.00 65.61  ? 193 ASN C CG  1 
ATOM   5473  O OD1 . ASN C 1 193 ? -13.525 11.869  18.210   1.00 68.60  ? 193 ASN C OD1 1 
ATOM   5474  N ND2 . ASN C 1 193 ? -14.045 9.875   17.319   1.00 77.10  ? 193 ASN C ND2 1 
ATOM   5475  N N   . LEU C 1 194 ? -12.134 13.546  13.497   1.00 50.39  ? 194 LEU C N   1 
ATOM   5476  C CA  . LEU C 1 194 ? -11.139 13.816  12.467   1.00 44.31  ? 194 LEU C CA  1 
ATOM   5477  C C   . LEU C 1 194 ? -10.959 15.305  12.198   1.00 54.86  ? 194 LEU C C   1 
ATOM   5478  O O   . LEU C 1 194 ? -9.836  15.752  11.941   1.00 50.24  ? 194 LEU C O   1 
ATOM   5479  C CB  . LEU C 1 194 ? -11.520 13.101  11.166   1.00 51.24  ? 194 LEU C CB  1 
ATOM   5480  C CG  . LEU C 1 194 ? -11.020 11.667  10.957   1.00 50.83  ? 194 LEU C CG  1 
ATOM   5481  C CD1 . LEU C 1 194 ? -11.521 10.734  12.049   1.00 56.48  ? 194 LEU C CD1 1 
ATOM   5482  C CD2 . LEU C 1 194 ? -11.435 11.153  9.586    1.00 41.46  ? 194 LEU C CD2 1 
ATOM   5483  N N   . TYR C 1 195 ? -12.038 16.087  12.260   1.00 48.34  ? 195 TYR C N   1 
ATOM   5484  C CA  . TYR C 1 195 ? -12.000 17.480  11.829   1.00 53.35  ? 195 TYR C CA  1 
ATOM   5485  C C   . TYR C 1 195 ? -12.507 18.483  12.855   1.00 49.60  ? 195 TYR C C   1 
ATOM   5486  O O   . TYR C 1 195 ? -12.301 19.685  12.651   1.00 56.24  ? 195 TYR C O   1 
ATOM   5487  C CB  . TYR C 1 195 ? -12.810 17.654  10.536   1.00 45.47  ? 195 TYR C CB  1 
ATOM   5488  C CG  . TYR C 1 195 ? -12.542 16.578  9.508    1.00 42.59  ? 195 TYR C CG  1 
ATOM   5489  C CD1 . TYR C 1 195 ? -11.318 16.504  8.853    1.00 47.23  ? 195 TYR C CD1 1 
ATOM   5490  C CD2 . TYR C 1 195 ? -13.514 15.638  9.189    1.00 47.82  ? 195 TYR C CD2 1 
ATOM   5491  C CE1 . TYR C 1 195 ? -11.068 15.520  7.910    1.00 41.71  ? 195 TYR C CE1 1 
ATOM   5492  C CE2 . TYR C 1 195 ? -13.274 14.651  8.247    1.00 43.80  ? 195 TYR C CE2 1 
ATOM   5493  C CZ  . TYR C 1 195 ? -12.050 14.598  7.611    1.00 48.06  ? 195 TYR C CZ  1 
ATOM   5494  O OH  . TYR C 1 195 ? -11.807 13.623  6.672    1.00 47.88  ? 195 TYR C OH  1 
ATOM   5495  N N   . LYS C 1 196 ? -13.217 18.049  13.899   1.00 55.60  ? 196 LYS C N   1 
ATOM   5496  C CA  . LYS C 1 196 ? -13.615 18.882  15.034   1.00 43.90  ? 196 LYS C CA  1 
ATOM   5497  C C   . LYS C 1 196 ? -14.695 19.894  14.655   1.00 48.64  ? 196 LYS C C   1 
ATOM   5498  O O   . LYS C 1 196 ? -15.344 20.477  15.529   1.00 78.94  ? 196 LYS C O   1 
ATOM   5499  C CB  . LYS C 1 196 ? -12.386 19.597  15.618   1.00 56.75  ? 196 LYS C CB  1 
ATOM   5500  C CG  . LYS C 1 196 ? -12.662 20.528  16.791   1.00 66.16  ? 196 LYS C CG  1 
ATOM   5501  C CD  . LYS C 1 196 ? -13.039 19.753  18.041   1.00 70.13  ? 196 LYS C CD  1 
ATOM   5502  C CE  . LYS C 1 196 ? -13.502 20.684  19.147   1.00 71.06  ? 196 LYS C CE  1 
ATOM   5503  N NZ  . LYS C 1 196 ? -14.794 21.338  18.803   1.00 77.86  ? 196 LYS C NZ  1 
ATOM   5504  N N   . ASN C 1 197 ? -14.953 20.055  13.359   1.00 58.43  ? 197 ASN C N   1 
ATOM   5505  C CA  . ASN C 1 197 ? -16.001 20.950  12.895   1.00 48.76  ? 197 ASN C CA  1 
ATOM   5506  C C   . ASN C 1 197 ? -17.183 20.112  12.446   1.00 54.15  ? 197 ASN C C   1 
ATOM   5507  O O   . ASN C 1 197 ? -17.019 19.271  11.548   1.00 46.53  ? 197 ASN C O   1 
ATOM   5508  C CB  . ASN C 1 197 ? -15.504 21.827  11.750   1.00 51.17  ? 197 ASN C CB  1 
ATOM   5509  C CG  . ASN C 1 197 ? -14.360 22.742  12.160   1.00 56.14  ? 197 ASN C CG  1 
ATOM   5510  O OD1 . ASN C 1 197 ? -14.314 23.237  13.286   1.00 47.45  ? 197 ASN C OD1 1 
ATOM   5511  N ND2 . ASN C 1 197 ? -13.431 22.975  11.241   1.00 46.19  ? 197 ASN C ND2 1 
ATOM   5512  N N   . PRO C 1 198 ? -18.369 20.274  13.040   1.00 57.96  ? 198 PRO C N   1 
ATOM   5513  C CA  . PRO C 1 198 ? -19.482 19.376  12.683   1.00 53.16  ? 198 PRO C CA  1 
ATOM   5514  C C   . PRO C 1 198 ? -20.005 19.582  11.272   1.00 57.85  ? 198 PRO C C   1 
ATOM   5515  O O   . PRO C 1 198 ? -20.269 18.598  10.569   1.00 61.59  ? 198 PRO C O   1 
ATOM   5516  C CB  . PRO C 1 198 ? -20.545 19.702  13.744   1.00 56.21  ? 198 PRO C CB  1 
ATOM   5517  C CG  . PRO C 1 198 ? -20.223 21.094  14.190   1.00 62.46  ? 198 PRO C CG  1 
ATOM   5518  C CD  . PRO C 1 198 ? -18.728 21.212  14.118   1.00 57.74  ? 198 PRO C CD  1 
ATOM   5519  N N   . ILE C 1 199 ? -20.170 20.828  10.835   1.00 50.95  ? 199 ILE C N   1 
ATOM   5520  C CA  . ILE C 1 199 ? -20.645 21.143  9.491    1.00 51.42  ? 199 ILE C CA  1 
ATOM   5521  C C   . ILE C 1 199 ? -19.490 21.773  8.726    1.00 48.99  ? 199 ILE C C   1 
ATOM   5522  O O   . ILE C 1 199 ? -18.929 22.786  9.161    1.00 55.01  ? 199 ILE C O   1 
ATOM   5523  C CB  . ILE C 1 199 ? -21.867 22.074  9.525    1.00 66.78  ? 199 ILE C CB  1 
ATOM   5524  C CG1 . ILE C 1 199 ? -23.019 21.413  10.283   1.00 64.07  ? 199 ILE C CG1 1 
ATOM   5525  C CG2 . ILE C 1 199 ? -22.300 22.443  8.114    1.00 47.25  ? 199 ILE C CG2 1 
ATOM   5526  C CD1 . ILE C 1 199 ? -23.420 22.143  11.543   1.00 69.85  ? 199 ILE C CD1 1 
ATOM   5527  N N   . THR C 1 200 ? -19.133 21.177  7.590    1.00 46.47  ? 200 THR C N   1 
ATOM   5528  C CA  . THR C 1 200 ? -17.951 21.577  6.842    1.00 43.60  ? 200 THR C CA  1 
ATOM   5529  C C   . THR C 1 200 ? -18.284 21.744  5.365    1.00 49.31  ? 200 THR C C   1 
ATOM   5530  O O   . THR C 1 200 ? -19.362 21.372  4.895    1.00 48.37  ? 200 THR C O   1 
ATOM   5531  C CB  . THR C 1 200 ? -16.810 20.561  7.000    1.00 45.80  ? 200 THR C CB  1 
ATOM   5532  O OG1 . THR C 1 200 ? -17.258 19.268  6.582    1.00 54.18  ? 200 THR C OG1 1 
ATOM   5533  C CG2 . THR C 1 200 ? -16.347 20.488  8.444    1.00 48.22  ? 200 THR C CG2 1 
ATOM   5534  N N   . TYR C 1 201 ? -17.324 22.307  4.634    1.00 43.41  ? 201 TYR C N   1 
ATOM   5535  C CA  . TYR C 1 201 ? -17.485 22.593  3.217    1.00 49.74  ? 201 TYR C CA  1 
ATOM   5536  C C   . TYR C 1 201 ? -16.108 22.638  2.569    1.00 40.66  ? 201 TYR C C   1 
ATOM   5537  O O   . TYR C 1 201 ? -15.084 22.750  3.248    1.00 44.34  ? 201 TYR C O   1 
ATOM   5538  C CB  . TYR C 1 201 ? -18.215 23.922  2.989    1.00 54.37  ? 201 TYR C CB  1 
ATOM   5539  C CG  . TYR C 1 201 ? -17.411 25.112  3.461    1.00 50.23  ? 201 TYR C CG  1 
ATOM   5540  C CD1 . TYR C 1 201 ? -17.422 25.495  4.796    1.00 48.89  ? 201 TYR C CD1 1 
ATOM   5541  C CD2 . TYR C 1 201 ? -16.624 25.841  2.576    1.00 47.54  ? 201 TYR C CD2 1 
ATOM   5542  C CE1 . TYR C 1 201 ? -16.680 26.572  5.237    1.00 55.61  ? 201 TYR C CE1 1 
ATOM   5543  C CE2 . TYR C 1 201 ? -15.879 26.922  3.006    1.00 48.85  ? 201 TYR C CE2 1 
ATOM   5544  C CZ  . TYR C 1 201 ? -15.910 27.282  4.338    1.00 56.96  ? 201 TYR C CZ  1 
ATOM   5545  O OH  . TYR C 1 201 ? -15.170 28.355  4.773    1.00 52.77  ? 201 TYR C OH  1 
ATOM   5546  N N   . ILE C 1 202 ? -16.102 22.545  1.241    1.00 38.51  ? 202 ILE C N   1 
ATOM   5547  C CA  . ILE C 1 202 ? -14.916 22.786  0.428    1.00 39.21  ? 202 ILE C CA  1 
ATOM   5548  C C   . ILE C 1 202 ? -15.309 23.724  -0.703   1.00 45.18  ? 202 ILE C C   1 
ATOM   5549  O O   . ILE C 1 202 ? -16.313 23.490  -1.385   1.00 48.97  ? 202 ILE C O   1 
ATOM   5550  C CB  . ILE C 1 202 ? -14.321 21.484  -0.142   1.00 41.11  ? 202 ILE C CB  1 
ATOM   5551  C CG1 . ILE C 1 202 ? -13.957 20.514  0.979    1.00 43.48  ? 202 ILE C CG1 1 
ATOM   5552  C CG2 . ILE C 1 202 ? -13.093 21.788  -0.987   1.00 42.01  ? 202 ILE C CG2 1 
ATOM   5553  C CD1 . ILE C 1 202 ? -13.374 19.217  0.480    1.00 45.86  ? 202 ILE C CD1 1 
ATOM   5554  N N   . SER C 1 203 ? -14.520 24.779  -0.902   1.00 45.00  ? 203 SER C N   1 
ATOM   5555  C CA  . SER C 1 203 ? -14.721 25.727  -1.991   1.00 43.25  ? 203 SER C CA  1 
ATOM   5556  C C   . SER C 1 203 ? -13.477 25.753  -2.866   1.00 41.77  ? 203 SER C C   1 
ATOM   5557  O O   . SER C 1 203 ? -12.357 25.883  -2.358   1.00 40.00  ? 203 SER C O   1 
ATOM   5558  C CB  . SER C 1 203 ? -15.025 27.130  -1.455   1.00 42.22  ? 203 SER C CB  1 
ATOM   5559  O OG  . SER C 1 203 ? -16.154 27.116  -0.595   1.00 54.23  ? 203 SER C OG  1 
ATOM   5560  N N   . VAL C 1 204 ? -13.670 25.607  -4.175   1.00 38.75  ? 204 VAL C N   1 
ATOM   5561  C CA  . VAL C 1 204 ? -12.580 25.620  -5.144   1.00 34.97  ? 204 VAL C CA  1 
ATOM   5562  C C   . VAL C 1 204 ? -12.967 26.586  -6.257   1.00 46.20  ? 204 VAL C C   1 
ATOM   5563  O O   . VAL C 1 204 ? -14.038 26.452  -6.854   1.00 40.34  ? 204 VAL C O   1 
ATOM   5564  C CB  . VAL C 1 204 ? -12.292 24.222  -5.721   1.00 41.07  ? 204 VAL C CB  1 
ATOM   5565  C CG1 . VAL C 1 204 ? -11.006 24.251  -6.540   1.00 41.61  ? 204 VAL C CG1 1 
ATOM   5566  C CG2 . VAL C 1 204 ? -12.195 23.190  -4.606   1.00 45.01  ? 204 VAL C CG2 1 
ATOM   5567  N N   . GLY C 1 205 ? -12.098 27.549  -6.531   1.00 40.95  ? 205 GLY C N   1 
ATOM   5568  C CA  . GLY C 1 205 ? -12.388 28.571  -7.520   1.00 36.29  ? 205 GLY C CA  1 
ATOM   5569  C C   . GLY C 1 205 ? -11.197 28.820  -8.419   1.00 40.89  ? 205 GLY C C   1 
ATOM   5570  O O   . GLY C 1 205 ? -10.050 28.815  -7.970   1.00 43.01  ? 205 GLY C O   1 
ATOM   5571  N N   . THR C 1 206 ? -11.487 29.071  -9.689   1.00 39.35  ? 206 THR C N   1 
ATOM   5572  C CA  . THR C 1 206 ? -10.516 29.502  -10.689  1.00 48.13  ? 206 THR C CA  1 
ATOM   5573  C C   . THR C 1 206 ? -11.216 30.565  -11.526  1.00 44.89  ? 206 THR C C   1 
ATOM   5574  O O   . THR C 1 206 ? -12.230 31.137  -11.112  1.00 53.42  ? 206 THR C O   1 
ATOM   5575  C CB  . THR C 1 206 ? -9.992  28.341  -11.556  1.00 45.03  ? 206 THR C CB  1 
ATOM   5576  O OG1 . THR C 1 206 ? -11.038 27.858  -12.409  1.00 44.00  ? 206 THR C OG1 1 
ATOM   5577  C CG2 . THR C 1 206 ? -9.449  27.192  -10.706  1.00 50.87  ? 206 THR C CG2 1 
ATOM   5578  N N   . SER C 1 207 ? -10.658 30.876  -12.697  1.00 44.27  ? 207 SER C N   1 
ATOM   5579  C CA  . SER C 1 207 ? -11.343 31.788  -13.607  1.00 46.48  ? 207 SER C CA  1 
ATOM   5580  C C   . SER C 1 207 ? -12.625 31.189  -14.174  1.00 47.05  ? 207 SER C C   1 
ATOM   5581  O O   . SER C 1 207 ? -13.518 31.940  -14.579  1.00 60.95  ? 207 SER C O   1 
ATOM   5582  C CB  . SER C 1 207 ? -10.411 32.194  -14.750  1.00 44.92  ? 207 SER C CB  1 
ATOM   5583  O OG  . SER C 1 207 ? -10.096 31.084  -15.572  1.00 60.79  ? 207 SER C OG  1 
ATOM   5584  N N   . THR C 1 208 ? -12.741 29.859  -14.206  1.00 52.10  ? 208 THR C N   1 
ATOM   5585  C CA  . THR C 1 208 ? -13.930 29.191  -14.715  1.00 44.11  ? 208 THR C CA  1 
ATOM   5586  C C   . THR C 1 208 ? -14.585 28.243  -13.720  1.00 56.71  ? 208 THR C C   1 
ATOM   5587  O O   . THR C 1 208 ? -15.782 27.969  -13.858  1.00 52.20  ? 208 THR C O   1 
ATOM   5588  C CB  . THR C 1 208 ? -13.602 28.402  -15.994  1.00 62.06  ? 208 THR C CB  1 
ATOM   5589  O OG1 . THR C 1 208 ? -12.497 27.523  -15.747  1.00 53.38  ? 208 THR C OG1 1 
ATOM   5590  C CG2 . THR C 1 208 ? -13.250 29.349  -17.141  1.00 37.64  ? 208 THR C CG2 1 
ATOM   5591  N N   . LEU C 1 209 ? -13.853 27.742  -12.731  1.00 48.86  ? 209 LEU C N   1 
ATOM   5592  C CA  . LEU C 1 209 ? -14.400 26.796  -11.769  1.00 44.70  ? 209 LEU C CA  1 
ATOM   5593  C C   . LEU C 1 209 ? -14.972 27.543  -10.571  1.00 51.96  ? 209 LEU C C   1 
ATOM   5594  O O   . LEU C 1 209 ? -14.324 28.438  -10.018  1.00 48.53  ? 209 LEU C O   1 
ATOM   5595  C CB  . LEU C 1 209 ? -13.325 25.808  -11.314  1.00 48.10  ? 209 LEU C CB  1 
ATOM   5596  C CG  . LEU C 1 209 ? -13.779 24.669  -10.402  1.00 52.28  ? 209 LEU C CG  1 
ATOM   5597  C CD1 . LEU C 1 209 ? -14.710 23.728  -11.144  1.00 42.38  ? 209 LEU C CD1 1 
ATOM   5598  C CD2 . LEU C 1 209 ? -12.580 23.915  -9.856   1.00 58.26  ? 209 LEU C CD2 1 
ATOM   5599  N N   . ASN C 1 210 ? -16.197 27.185  -10.189  1.00 54.00  ? 210 ASN C N   1 
ATOM   5600  C CA  . ASN C 1 210 ? -16.871 27.748  -9.015   1.00 50.31  ? 210 ASN C CA  1 
ATOM   5601  C C   . ASN C 1 210 ? -17.593 26.582  -8.340   1.00 52.79  ? 210 ASN C C   1 
ATOM   5602  O O   . ASN C 1 210 ? -18.766 26.320  -8.614   1.00 52.68  ? 210 ASN C O   1 
ATOM   5603  C CB  . ASN C 1 210 ? -17.825 28.865  -9.423   1.00 47.72  ? 210 ASN C CB  1 
ATOM   5604  C CG  . ASN C 1 210 ? -18.529 29.501  -8.243   1.00 48.72  ? 210 ASN C CG  1 
ATOM   5605  O OD1 . ASN C 1 210 ? -18.052 29.445  -7.110   1.00 43.46  ? 210 ASN C OD1 1 
ATOM   5606  N ND2 . ASN C 1 210 ? -19.673 30.122  -8.509   1.00 52.57  ? 210 ASN C ND2 1 
ATOM   5607  N N   . GLN C 1 211 ? -16.890 25.897  -7.443   1.00 41.86  ? 211 GLN C N   1 
ATOM   5608  C CA  . GLN C 1 211 ? -17.352 24.636  -6.880   1.00 42.95  ? 211 GLN C CA  1 
ATOM   5609  C C   . GLN C 1 211 ? -17.485 24.748  -5.369   1.00 45.81  ? 211 GLN C C   1 
ATOM   5610  O O   . GLN C 1 211 ? -16.594 25.280  -4.700   1.00 47.55  ? 211 GLN C O   1 
ATOM   5611  C CB  . GLN C 1 211 ? -16.391 23.502  -7.241   1.00 43.41  ? 211 GLN C CB  1 
ATOM   5612  C CG  . GLN C 1 211 ? -16.626 22.211  -6.481   1.00 51.58  ? 211 GLN C CG  1 
ATOM   5613  C CD  . GLN C 1 211 ? -15.594 21.154  -6.817   1.00 64.89  ? 211 GLN C CD  1 
ATOM   5614  O OE1 . GLN C 1 211 ? -14.724 20.837  -6.003   1.00 46.47  ? 211 GLN C OE1 1 
ATOM   5615  N NE2 . GLN C 1 211 ? -15.680 20.606  -8.025   1.00 61.56  ? 211 GLN C NE2 1 
ATOM   5616  N N   . ARG C 1 212 ? -18.598 24.243  -4.839   1.00 47.80  ? 212 ARG C N   1 
ATOM   5617  C CA  . ARG C 1 212 ? -18.786 24.092  -3.404   1.00 50.70  ? 212 ARG C CA  1 
ATOM   5618  C C   . ARG C 1 212 ? -19.208 22.660  -3.112   1.00 50.09  ? 212 ARG C C   1 
ATOM   5619  O O   . ARG C 1 212 ? -20.093 22.121  -3.783   1.00 54.64  ? 212 ARG C O   1 
ATOM   5620  C CB  . ARG C 1 212 ? -19.825 25.076  -2.867   1.00 48.30  ? 212 ARG C CB  1 
ATOM   5621  C CG  . ARG C 1 212 ? -19.700 25.324  -1.377   1.00 51.49  ? 212 ARG C CG  1 
ATOM   5622  C CD  . ARG C 1 212 ? -20.035 26.764  -1.042   1.00 73.03  ? 212 ARG C CD  1 
ATOM   5623  N NE  . ARG C 1 212 ? -19.692 27.098  0.334    1.00 71.66  ? 212 ARG C NE  1 
ATOM   5624  C CZ  . ARG C 1 212 ? -20.440 26.793  1.385    1.00 77.52  ? 212 ARG C CZ  1 
ATOM   5625  N NH1 . ARG C 1 212 ? -21.574 26.123  1.255    1.00 75.76  ? 212 ARG C NH1 1 
ATOM   5626  N NH2 . ARG C 1 212 ? -20.041 27.168  2.597    1.00 75.54  ? 212 ARG C NH2 1 
ATOM   5627  N N   . LEU C 1 213 ? -18.570 22.049  -2.117   1.00 53.07  ? 213 LEU C N   1 
ATOM   5628  C CA  . LEU C 1 213 ? -18.835 20.669  -1.740   1.00 45.85  ? 213 LEU C CA  1 
ATOM   5629  C C   . LEU C 1 213 ? -19.125 20.591  -0.251   1.00 52.04  ? 213 LEU C C   1 
ATOM   5630  O O   . LEU C 1 213 ? -18.576 21.358  0.544    1.00 60.91  ? 213 LEU C O   1 
ATOM   5631  C CB  . LEU C 1 213 ? -17.648 19.754  -2.066   1.00 50.57  ? 213 LEU C CB  1 
ATOM   5632  C CG  . LEU C 1 213 ? -17.133 19.740  -3.503   1.00 57.60  ? 213 LEU C CG  1 
ATOM   5633  C CD1 . LEU C 1 213 ? -15.811 18.996  -3.565   1.00 53.49  ? 213 LEU C CD1 1 
ATOM   5634  C CD2 . LEU C 1 213 ? -18.158 19.104  -4.423   1.00 46.51  ? 213 LEU C CD2 1 
ATOM   5635  N N   . ALA C 1 214 ? -19.990 19.650  0.121    1.00 43.97  ? 214 ALA C N   1 
ATOM   5636  C CA  . ALA C 1 214 ? -20.242 19.340  1.517    1.00 51.08  ? 214 ALA C CA  1 
ATOM   5637  C C   . ALA C 1 214 ? -20.206 17.831  1.713    1.00 46.77  ? 214 ALA C C   1 
ATOM   5638  O O   . ALA C 1 214 ? -20.618 17.078  0.823    1.00 46.63  ? 214 ALA C O   1 
ATOM   5639  C CB  . ALA C 1 214 ? -21.598 19.895  1.978    1.00 51.79  ? 214 ALA C CB  1 
ATOM   5640  N N   . PRO C 1 215 ? -19.709 17.361  2.853    1.00 43.98  ? 215 PRO C N   1 
ATOM   5641  C CA  . PRO C 1 215 ? -19.686 15.917  3.103    1.00 50.96  ? 215 PRO C CA  1 
ATOM   5642  C C   . PRO C 1 215 ? -21.089 15.348  3.211    1.00 57.97  ? 215 PRO C C   1 
ATOM   5643  O O   . PRO C 1 215 ? -22.023 16.011  3.667    1.00 52.03  ? 215 PRO C O   1 
ATOM   5644  C CB  . PRO C 1 215 ? -18.938 15.796  4.437    1.00 51.23  ? 215 PRO C CB  1 
ATOM   5645  C CG  . PRO C 1 215 ? -18.181 17.072  4.565    1.00 57.49  ? 215 PRO C CG  1 
ATOM   5646  C CD  . PRO C 1 215 ? -19.030 18.116  3.918    1.00 42.31  ? 215 PRO C CD  1 
ATOM   5647  N N   . LYS C 1 216 ? -21.225 14.097  2.786    1.00 48.87  ? 216 LYS C N   1 
ATOM   5648  C CA  . LYS C 1 216 ? -22.477 13.352  2.877    1.00 45.67  ? 216 LYS C CA  1 
ATOM   5649  C C   . LYS C 1 216 ? -22.268 12.246  3.907    1.00 56.81  ? 216 LYS C C   1 
ATOM   5650  O O   . LYS C 1 216 ? -21.808 11.151  3.582    1.00 53.26  ? 216 LYS C O   1 
ATOM   5651  C CB  . LYS C 1 216 ? -22.887 12.802  1.511    1.00 47.27  ? 216 LYS C CB  1 
ATOM   5652  C CG  . LYS C 1 216 ? -23.293 13.885  0.520    1.00 50.88  ? 216 LYS C CG  1 
ATOM   5653  C CD  . LYS C 1 216 ? -23.702 13.306  -0.824   1.00 48.45  ? 216 LYS C CD  1 
ATOM   5654  C CE  . LYS C 1 216 ? -22.504 12.773  -1.590   1.00 61.68  ? 216 LYS C CE  1 
ATOM   5655  N NZ  . LYS C 1 216 ? -22.877 12.343  -2.968   1.00 56.73  ? 216 LYS C NZ  1 
ATOM   5656  N N   . ILE C 1 217 ? -22.606 12.545  5.157    1.00 57.98  ? 217 ILE C N   1 
ATOM   5657  C CA  . ILE C 1 217 ? -22.421 11.606  6.259    1.00 64.80  ? 217 ILE C CA  1 
ATOM   5658  C C   . ILE C 1 217 ? -23.587 10.623  6.240    1.00 77.78  ? 217 ILE C C   1 
ATOM   5659  O O   . ILE C 1 217 ? -24.738 11.006  6.459    1.00 76.41  ? 217 ILE C O   1 
ATOM   5660  C CB  . ILE C 1 217 ? -22.326 12.335  7.603    1.00 63.56  ? 217 ILE C CB  1 
ATOM   5661  C CG1 . ILE C 1 217 ? -21.066 13.205  7.642    1.00 65.58  ? 217 ILE C CG1 1 
ATOM   5662  C CG2 . ILE C 1 217 ? -22.341 11.342  8.751    1.00 75.09  ? 217 ILE C CG2 1 
ATOM   5663  C CD1 . ILE C 1 217 ? -20.984 14.120  8.843    1.00 67.64  ? 217 ILE C CD1 1 
ATOM   5664  N N   . ALA C 1 218 ? -23.291 9.352   5.976    1.00 73.30  ? 218 ALA C N   1 
ATOM   5665  C CA  . ALA C 1 218 ? -24.331 8.341   5.835    1.00 71.43  ? 218 ALA C CA  1 
ATOM   5666  C C   . ALA C 1 218 ? -23.737 6.966   6.107    1.00 71.36  ? 218 ALA C C   1 
ATOM   5667  O O   . ALA C 1 218 ? -22.517 6.783   6.130    1.00 62.37  ? 218 ALA C O   1 
ATOM   5668  C CB  . ALA C 1 218 ? -24.971 8.391   4.446    1.00 46.08  ? 218 ALA C CB  1 
ATOM   5669  N N   . THR C 1 219 ? -24.626 5.997   6.311    1.00 77.48  ? 219 THR C N   1 
ATOM   5670  C CA  . THR C 1 219 ? -24.237 4.613   6.547    1.00 54.28  ? 219 THR C CA  1 
ATOM   5671  C C   . THR C 1 219 ? -24.067 3.909   5.206    1.00 48.50  ? 219 THR C C   1 
ATOM   5672  O O   . THR C 1 219 ? -24.993 3.891   4.389    1.00 57.68  ? 219 THR C O   1 
ATOM   5673  C CB  . THR C 1 219 ? -25.284 3.896   7.398    1.00 53.70  ? 219 THR C CB  1 
ATOM   5674  O OG1 . THR C 1 219 ? -25.437 4.579   8.649    1.00 60.03  ? 219 THR C OG1 1 
ATOM   5675  C CG2 . THR C 1 219 ? -24.864 2.457   7.658    1.00 58.75  ? 219 THR C CG2 1 
ATOM   5676  N N   . ARG C 1 220 ? -22.888 3.331   4.984    1.00 46.12  ? 220 ARG C N   1 
ATOM   5677  C CA  . ARG C 1 220 ? -22.556 2.679   3.727    1.00 47.62  ? 220 ARG C CA  1 
ATOM   5678  C C   . ARG C 1 220 ? -21.959 1.308   4.005    1.00 55.97  ? 220 ARG C C   1 
ATOM   5679  O O   . ARG C 1 220 ? -21.526 1.010   5.120    1.00 60.38  ? 220 ARG C O   1 
ATOM   5680  C CB  . ARG C 1 220 ? -21.568 3.514   2.902    1.00 46.73  ? 220 ARG C CB  1 
ATOM   5681  C CG  . ARG C 1 220 ? -21.950 4.975   2.778    1.00 54.96  ? 220 ARG C CG  1 
ATOM   5682  C CD  . ARG C 1 220 ? -20.767 5.826   2.355    1.00 44.85  ? 220 ARG C CD  1 
ATOM   5683  N NE  . ARG C 1 220 ? -20.996 7.235   2.648    1.00 58.44  ? 220 ARG C NE  1 
ATOM   5684  C CZ  . ARG C 1 220 ? -20.492 7.874   3.694    1.00 56.56  ? 220 ARG C CZ  1 
ATOM   5685  N NH1 . ARG C 1 220 ? -19.680 7.272   4.549    1.00 52.99  ? 220 ARG C NH1 1 
ATOM   5686  N NH2 . ARG C 1 220 ? -20.807 9.151   3.887    1.00 65.73  ? 220 ARG C NH2 1 
ATOM   5687  N N   . SER C 1 221 ? -21.946 0.472   2.969    1.00 50.29  ? 221 SER C N   1 
ATOM   5688  C CA  . SER C 1 221 ? -21.325 -0.841  3.053    1.00 53.50  ? 221 SER C CA  1 
ATOM   5689  C C   . SER C 1 221 ? -19.804 -0.723  2.992    1.00 57.90  ? 221 SER C C   1 
ATOM   5690  O O   . SER C 1 221 ? -19.246 0.235   2.451    1.00 61.51  ? 221 SER C O   1 
ATOM   5691  C CB  . SER C 1 221 ? -21.824 -1.745  1.926    1.00 46.74  ? 221 SER C CB  1 
ATOM   5692  O OG  . SER C 1 221 ? -23.230 -1.909  1.994    1.00 61.49  ? 221 SER C OG  1 
ATOM   5693  N N   . GLN C 1 222 ? -19.132 -1.723  3.556    1.00 65.34  ? 222 GLN C N   1 
ATOM   5694  C CA  . GLN C 1 222 ? -17.676 -1.723  3.587    1.00 45.80  ? 222 GLN C CA  1 
ATOM   5695  C C   . GLN C 1 222 ? -17.106 -2.052  2.214    1.00 53.23  ? 222 GLN C C   1 
ATOM   5696  O O   . GLN C 1 222 ? -17.532 -3.011  1.563    1.00 57.94  ? 222 GLN C O   1 
ATOM   5697  C CB  . GLN C 1 222 ? -17.163 -2.730  4.615    1.00 50.76  ? 222 GLN C CB  1 
ATOM   5698  C CG  . GLN C 1 222 ? -17.395 -2.329  6.056    1.00 62.84  ? 222 GLN C CG  1 
ATOM   5699  C CD  . GLN C 1 222 ? -16.923 -3.388  7.032    1.00 78.69  ? 222 GLN C CD  1 
ATOM   5700  O OE1 . GLN C 1 222 ? -15.817 -3.308  7.569    1.00 65.24  ? 222 GLN C OE1 1 
ATOM   5701  N NE2 . GLN C 1 222 ? -17.761 -4.393  7.266    1.00 75.89  ? 222 GLN C NE2 1 
ATOM   5702  N N   . VAL C 1 223 ? -16.146 -1.244  1.773    1.00 55.33  ? 223 VAL C N   1 
ATOM   5703  C CA  . VAL C 1 223 ? -15.349 -1.518  0.583    1.00 49.87  ? 223 VAL C CA  1 
ATOM   5704  C C   . VAL C 1 223 ? -13.889 -1.344  0.973    1.00 52.32  ? 223 VAL C C   1 
ATOM   5705  O O   . VAL C 1 223 ? -13.505 -0.284  1.483    1.00 60.21  ? 223 VAL C O   1 
ATOM   5706  C CB  . VAL C 1 223 ? -15.711 -0.593  -0.593   1.00 52.20  ? 223 VAL C CB  1 
ATOM   5707  C CG1 . VAL C 1 223 ? -14.851 -0.919  -1.808   1.00 39.69  ? 223 VAL C CG1 1 
ATOM   5708  C CG2 . VAL C 1 223 ? -17.189 -0.715  -0.936   1.00 44.57  ? 223 VAL C CG2 1 
ATOM   5709  N N   . ASN C 1 224 ? -13.084 -2.383  0.746    1.00 52.65  ? 224 ASN C N   1 
ATOM   5710  C CA  . ASN C 1 224 ? -11.682 -2.404  1.172    1.00 54.04  ? 224 ASN C CA  1 
ATOM   5711  C C   . ASN C 1 224 ? -11.553 -2.121  2.667    1.00 49.48  ? 224 ASN C C   1 
ATOM   5712  O O   . ASN C 1 224 ? -10.588 -1.498  3.117    1.00 56.51  ? 224 ASN C O   1 
ATOM   5713  C CB  . ASN C 1 224 ? -10.834 -1.423  0.357    1.00 51.61  ? 224 ASN C CB  1 
ATOM   5714  C CG  . ASN C 1 224 ? -10.841 -1.741  -1.125   1.00 58.28  ? 224 ASN C CG  1 
ATOM   5715  O OD1 . ASN C 1 224 ? -11.181 -2.852  -1.530   1.00 73.31  ? 224 ASN C OD1 1 
ATOM   5716  N ND2 . ASN C 1 224 ? -10.459 -0.766  -1.944   1.00 60.95  ? 224 ASN C ND2 1 
ATOM   5717  N N   . GLY C 1 225 ? -12.532 -2.581  3.445    1.00 57.19  ? 225 GLY C N   1 
ATOM   5718  C CA  . GLY C 1 225 ? -12.517 -2.435  4.883    1.00 40.11  ? 225 GLY C CA  1 
ATOM   5719  C C   . GLY C 1 225 ? -13.046 -1.122  5.420    1.00 55.86  ? 225 GLY C C   1 
ATOM   5720  O O   . GLY C 1 225 ? -13.088 -0.950  6.645    1.00 60.61  ? 225 GLY C O   1 
ATOM   5721  N N   . GLN C 1 226 ? -13.462 -0.196  4.560    1.00 56.71  ? 226 GLN C N   1 
ATOM   5722  C CA  . GLN C 1 226 ? -13.862 1.139   4.986    1.00 48.05  ? 226 GLN C CA  1 
ATOM   5723  C C   . GLN C 1 226 ? -15.282 1.451   4.537    1.00 44.50  ? 226 GLN C C   1 
ATOM   5724  O O   . GLN C 1 226 ? -15.667 1.156   3.401    1.00 48.36  ? 226 GLN C O   1 
ATOM   5725  C CB  . GLN C 1 226 ? -12.905 2.200   4.434    1.00 55.79  ? 226 GLN C CB  1 
ATOM   5726  C CG  . GLN C 1 226 ? -11.477 2.032   4.907    1.00 48.30  ? 226 GLN C CG  1 
ATOM   5727  C CD  . GLN C 1 226 ? -11.376 1.988   6.418    1.00 61.02  ? 226 GLN C CD  1 
ATOM   5728  O OE1 . GLN C 1 226 ? -12.015 2.775   7.118    1.00 60.94  ? 226 GLN C OE1 1 
ATOM   5729  N NE2 . GLN C 1 226 ? -10.567 1.067   6.930    1.00 65.36  ? 226 GLN C NE2 1 
ATOM   5730  N N   . ARG C 1 227 ? -16.055 2.055   5.440    1.00 53.31  ? 227 ARG C N   1 
ATOM   5731  C CA  . ARG C 1 227 ? -17.379 2.563   5.113    1.00 56.42  ? 227 ARG C CA  1 
ATOM   5732  C C   . ARG C 1 227 ? -17.358 4.015   4.656    1.00 52.74  ? 227 ARG C C   1 
ATOM   5733  O O   . ARG C 1 227 ? -18.370 4.497   4.134    1.00 49.93  ? 227 ARG C O   1 
ATOM   5734  C CB  . ARG C 1 227 ? -18.320 2.425   6.315    1.00 49.97  ? 227 ARG C CB  1 
ATOM   5735  C CG  . ARG C 1 227 ? -18.608 0.989   6.710    1.00 59.39  ? 227 ARG C CG  1 
ATOM   5736  C CD  . ARG C 1 227 ? -19.663 0.909   7.805    1.00 57.86  ? 227 ARG C CD  1 
ATOM   5737  N NE  . ARG C 1 227 ? -19.849 -0.460  8.274    1.00 71.35  ? 227 ARG C NE  1 
ATOM   5738  C CZ  . ARG C 1 227 ? -20.744 -1.308  7.783    1.00 72.57  ? 227 ARG C CZ  1 
ATOM   5739  N NH1 . ARG C 1 227 ? -21.576 -0.953  6.817    1.00 60.80  ? 227 ARG C NH1 1 
ATOM   5740  N NH2 . ARG C 1 227 ? -20.805 -2.542  8.275    1.00 76.93  ? 227 ARG C NH2 1 
ATOM   5741  N N   . GLY C 1 228 ? -16.246 4.719   4.844    1.00 45.92  ? 228 GLY C N   1 
ATOM   5742  C CA  . GLY C 1 228 ? -16.117 6.063   4.326    1.00 49.16  ? 228 GLY C CA  1 
ATOM   5743  C C   . GLY C 1 228 ? -15.902 6.068   2.824    1.00 54.33  ? 228 GLY C C   1 
ATOM   5744  O O   . GLY C 1 228 ? -15.673 5.038   2.189    1.00 49.26  ? 228 GLY C O   1 
ATOM   5745  N N   . ARG C 1 229 ? -15.991 7.264   2.244    1.00 47.76  ? 229 ARG C N   1 
ATOM   5746  C CA  . ARG C 1 229 ? -15.821 7.445   0.809    1.00 41.42  ? 229 ARG C CA  1 
ATOM   5747  C C   . ARG C 1 229 ? -15.039 8.723   0.546    1.00 42.62  ? 229 ARG C C   1 
ATOM   5748  O O   . ARG C 1 229 ? -15.074 9.666   1.340    1.00 42.94  ? 229 ARG C O   1 
ATOM   5749  C CB  . ARG C 1 229 ? -17.169 7.514   0.077    1.00 42.45  ? 229 ARG C CB  1 
ATOM   5750  C CG  . ARG C 1 229 ? -18.026 6.264   0.196    1.00 45.87  ? 229 ARG C CG  1 
ATOM   5751  C CD  . ARG C 1 229 ? -17.394 5.076   -0.503   1.00 37.48  ? 229 ARG C CD  1 
ATOM   5752  N NE  . ARG C 1 229 ? -18.229 3.885   -0.396   1.00 52.15  ? 229 ARG C NE  1 
ATOM   5753  C CZ  . ARG C 1 229 ? -18.083 2.946   0.530    1.00 55.51  ? 229 ARG C CZ  1 
ATOM   5754  N NH1 . ARG C 1 229 ? -17.128 3.017   1.444    1.00 49.00  ? 229 ARG C NH1 1 
ATOM   5755  N NH2 . ARG C 1 229 ? -18.913 1.907   0.536    1.00 55.88  ? 229 ARG C NH2 1 
ATOM   5756  N N   . MET C 1 230 ? -14.340 8.751   -0.587   1.00 54.95  ? 230 MET C N   1 
ATOM   5757  C CA  . MET C 1 230 ? -13.635 9.945   -1.034   1.00 46.26  ? 230 MET C CA  1 
ATOM   5758  C C   . MET C 1 230 ? -13.975 10.212  -2.490   1.00 45.85  ? 230 MET C C   1 
ATOM   5759  O O   . MET C 1 230 ? -13.712 9.371   -3.356   1.00 47.76  ? 230 MET C O   1 
ATOM   5760  C CB  . MET C 1 230 ? -12.126 9.800   -0.855   1.00 46.88  ? 230 MET C CB  1 
ATOM   5761  C CG  . MET C 1 230 ? -11.697 9.945   0.578    1.00 48.65  ? 230 MET C CG  1 
ATOM   5762  S SD  . MET C 1 230 ? -9.918  9.928   0.754    1.00 56.99  ? 230 MET C SD  1 
ATOM   5763  C CE  . MET C 1 230 ? -9.798  9.967   2.530    1.00 54.40  ? 230 MET C CE  1 
ATOM   5764  N N   . ASP C 1 231 ? -14.543 11.383  -2.755   1.00 42.07  ? 231 ASP C N   1 
ATOM   5765  C CA  . ASP C 1 231 ? -14.857 11.820  -4.108   1.00 46.79  ? 231 ASP C CA  1 
ATOM   5766  C C   . ASP C 1 231 ? -13.774 12.782  -4.570   1.00 45.56  ? 231 ASP C C   1 
ATOM   5767  O O   . ASP C 1 231 ? -13.514 13.794  -3.910   1.00 44.29  ? 231 ASP C O   1 
ATOM   5768  C CB  . ASP C 1 231 ? -16.230 12.489  -4.161   1.00 40.32  ? 231 ASP C CB  1 
ATOM   5769  C CG  . ASP C 1 231 ? -17.363 11.513  -3.909   1.00 55.79  ? 231 ASP C CG  1 
ATOM   5770  O OD1 . ASP C 1 231 ? -17.240 10.342  -4.328   1.00 59.50  ? 231 ASP C OD1 1 
ATOM   5771  O OD2 . ASP C 1 231 ? -18.374 11.916  -3.293   1.00 67.65  ? 231 ASP C OD2 1 
ATOM   5772  N N   . PHE C 1 232 ? -13.147 12.470  -5.697   1.00 38.94  ? 232 PHE C N   1 
ATOM   5773  C CA  . PHE C 1 232 ? -12.076 13.284  -6.245   1.00 42.44  ? 232 PHE C CA  1 
ATOM   5774  C C   . PHE C 1 232 ? -12.564 14.037  -7.476   1.00 40.35  ? 232 PHE C C   1 
ATOM   5775  O O   . PHE C 1 232 ? -13.450 13.575  -8.200   1.00 45.28  ? 232 PHE C O   1 
ATOM   5776  C CB  . PHE C 1 232 ? -10.852 12.428  -6.596   1.00 39.00  ? 232 PHE C CB  1 
ATOM   5777  C CG  . PHE C 1 232 ? -10.109 11.918  -5.392   1.00 47.41  ? 232 PHE C CG  1 
ATOM   5778  C CD1 . PHE C 1 232 ? -9.191  12.722  -4.739   1.00 42.08  ? 232 PHE C CD1 1 
ATOM   5779  C CD2 . PHE C 1 232 ? -10.334 10.641  -4.911   1.00 47.56  ? 232 PHE C CD2 1 
ATOM   5780  C CE1 . PHE C 1 232 ? -8.508  12.260  -3.626   1.00 51.57  ? 232 PHE C CE1 1 
ATOM   5781  C CE2 . PHE C 1 232 ? -9.655  10.172  -3.801   1.00 40.34  ? 232 PHE C CE2 1 
ATOM   5782  C CZ  . PHE C 1 232 ? -8.741  10.984  -3.158   1.00 40.28  ? 232 PHE C CZ  1 
ATOM   5783  N N   . PHE C 1 233 ? -11.978 15.213  -7.692   1.00 35.44  ? 233 PHE C N   1 
ATOM   5784  C CA  . PHE C 1 233 ? -12.348 16.093  -8.790   1.00 39.27  ? 233 PHE C CA  1 
ATOM   5785  C C   . PHE C 1 233 ? -11.076 16.627  -9.428   1.00 40.94  ? 233 PHE C C   1 
ATOM   5786  O O   . PHE C 1 233 ? -10.000 16.598  -8.825   1.00 42.96  ? 233 PHE C O   1 
ATOM   5787  C CB  . PHE C 1 233 ? -13.240 17.247  -8.308   1.00 34.31  ? 233 PHE C CB  1 
ATOM   5788  C CG  . PHE C 1 233 ? -14.465 16.796  -7.558   1.00 35.04  ? 233 PHE C CG  1 
ATOM   5789  C CD1 . PHE C 1 233 ? -14.397 16.493  -6.206   1.00 40.51  ? 233 PHE C CD1 1 
ATOM   5790  C CD2 . PHE C 1 233 ? -15.685 16.681  -8.204   1.00 37.02  ? 233 PHE C CD2 1 
ATOM   5791  C CE1 . PHE C 1 233 ? -15.520 16.074  -5.515   1.00 40.65  ? 233 PHE C CE1 1 
ATOM   5792  C CE2 . PHE C 1 233 ? -16.812 16.262  -7.520   1.00 33.34  ? 233 PHE C CE2 1 
ATOM   5793  C CZ  . PHE C 1 233 ? -16.729 15.961  -6.172   1.00 34.09  ? 233 PHE C CZ  1 
ATOM   5794  N N   . TRP C 1 234 ? -11.201 17.111  -10.663  1.00 37.68  ? 234 TRP C N   1 
ATOM   5795  C CA  . TRP C 1 234 ? -10.048 17.601  -11.403  1.00 40.22  ? 234 TRP C CA  1 
ATOM   5796  C C   . TRP C 1 234 ? -10.428 18.823  -12.226  1.00 50.07  ? 234 TRP C C   1 
ATOM   5797  O O   . TRP C 1 234 ? -11.583 18.992  -12.624  1.00 44.35  ? 234 TRP C O   1 
ATOM   5798  C CB  . TRP C 1 234 ? -9.463  16.519  -12.322  1.00 37.11  ? 234 TRP C CB  1 
ATOM   5799  C CG  . TRP C 1 234 ? -10.421 16.025  -13.368  1.00 41.79  ? 234 TRP C CG  1 
ATOM   5800  C CD1 . TRP C 1 234 ? -11.376 15.064  -13.213  1.00 39.99  ? 234 TRP C CD1 1 
ATOM   5801  C CD2 . TRP C 1 234 ? -10.513 16.464  -14.732  1.00 39.99  ? 234 TRP C CD2 1 
ATOM   5802  N NE1 . TRP C 1 234 ? -12.057 14.877  -14.394  1.00 47.40  ? 234 TRP C NE1 1 
ATOM   5803  C CE2 . TRP C 1 234 ? -11.546 15.725  -15.340  1.00 40.12  ? 234 TRP C CE2 1 
ATOM   5804  C CE3 . TRP C 1 234 ? -9.822  17.410  -15.495  1.00 45.56  ? 234 TRP C CE3 1 
ATOM   5805  C CZ2 . TRP C 1 234 ? -11.905 15.904  -16.676  1.00 47.93  ? 234 TRP C CZ2 1 
ATOM   5806  C CZ3 . TRP C 1 234 ? -10.179 17.584  -16.823  1.00 45.24  ? 234 TRP C CZ3 1 
ATOM   5807  C CH2 . TRP C 1 234 ? -11.211 16.835  -17.399  1.00 45.88  ? 234 TRP C CH2 1 
ATOM   5808  N N   . THR C 1 235 ? -9.433  19.672  -12.482  1.00 43.91  ? 235 THR C N   1 
ATOM   5809  C CA  . THR C 1 235 ? -9.602  20.822  -13.358  1.00 44.61  ? 235 THR C CA  1 
ATOM   5810  C C   . THR C 1 235 ? -8.295  21.070  -14.096  1.00 44.38  ? 235 THR C C   1 
ATOM   5811  O O   . THR C 1 235 ? -7.233  20.582  -13.700  1.00 45.94  ? 235 THR C O   1 
ATOM   5812  C CB  . THR C 1 235 ? -10.028 22.079  -12.585  1.00 49.34  ? 235 THR C CB  1 
ATOM   5813  O OG1 . THR C 1 235 ? -10.643 23.007  -13.487  1.00 46.12  ? 235 THR C OG1 1 
ATOM   5814  C CG2 . THR C 1 235 ? -8.823  22.751  -11.934  1.00 37.81  ? 235 THR C CG2 1 
ATOM   5815  N N   . ILE C 1 236 ? -8.389  21.821  -15.187  1.00 43.25  ? 236 ILE C N   1 
ATOM   5816  C CA  . ILE C 1 236 ? -7.227  22.241  -15.962  1.00 42.83  ? 236 ILE C CA  1 
ATOM   5817  C C   . ILE C 1 236 ? -6.989  23.715  -15.661  1.00 49.16  ? 236 ILE C C   1 
ATOM   5818  O O   . ILE C 1 236 ? -7.807  24.571  -16.021  1.00 53.40  ? 236 ILE C O   1 
ATOM   5819  C CB  . ILE C 1 236 ? -7.425  22.004  -17.466  1.00 46.63  ? 236 ILE C CB  1 
ATOM   5820  C CG1 . ILE C 1 236 ? -7.574  20.508  -17.755  1.00 52.14  ? 236 ILE C CG1 1 
ATOM   5821  C CG2 . ILE C 1 236 ? -6.268  22.598  -18.254  1.00 44.06  ? 236 ILE C CG2 1 
ATOM   5822  C CD1 . ILE C 1 236 ? -6.382  19.679  -17.320  1.00 48.39  ? 236 ILE C CD1 1 
ATOM   5823  N N   . LEU C 1 237 ? -5.874  24.016  -15.001  1.00 47.05  ? 237 LEU C N   1 
ATOM   5824  C CA  . LEU C 1 237 ? -5.532  25.388  -14.638  1.00 41.86  ? 237 LEU C CA  1 
ATOM   5825  C C   . LEU C 1 237 ? -4.657  25.977  -15.739  1.00 42.00  ? 237 LEU C C   1 
ATOM   5826  O O   . LEU C 1 237 ? -3.536  25.512  -15.970  1.00 42.81  ? 237 LEU C O   1 
ATOM   5827  C CB  . LEU C 1 237 ? -4.827  25.433  -13.284  1.00 41.08  ? 237 LEU C CB  1 
ATOM   5828  C CG  . LEU C 1 237 ? -4.577  26.821  -12.692  1.00 45.35  ? 237 LEU C CG  1 
ATOM   5829  C CD1 . LEU C 1 237 ? -5.893  27.524  -12.388  1.00 47.84  ? 237 LEU C CD1 1 
ATOM   5830  C CD2 . LEU C 1 237 ? -3.716  26.727  -11.440  1.00 43.67  ? 237 LEU C CD2 1 
ATOM   5831  N N   . LYS C 1 238 ? -5.178  26.989  -16.427  1.00 41.22  ? 238 LYS C N   1 
ATOM   5832  C CA  . LYS C 1 238 ? -4.453  27.617  -17.518  1.00 59.85  ? 238 LYS C CA  1 
ATOM   5833  C C   . LYS C 1 238 ? -3.293  28.447  -16.975  1.00 56.58  ? 238 LYS C C   1 
ATOM   5834  O O   . LYS C 1 238 ? -3.307  28.866  -15.814  1.00 44.49  ? 238 LYS C O   1 
ATOM   5835  C CB  . LYS C 1 238 ? -5.396  28.492  -18.340  1.00 46.46  ? 238 LYS C CB  1 
ATOM   5836  C CG  . LYS C 1 238 ? -6.300  27.700  -19.271  1.00 57.34  ? 238 LYS C CG  1 
ATOM   5837  C CD  . LYS C 1 238 ? -7.620  28.413  -19.503  1.00 77.14  ? 238 LYS C CD  1 
ATOM   5838  C CE  . LYS C 1 238 ? -7.895  28.614  -20.985  1.00 84.61  ? 238 LYS C CE  1 
ATOM   5839  N NZ  . LYS C 1 238 ? -9.296  29.058  -21.235  1.00 85.16  ? 238 LYS C NZ  1 
ATOM   5840  N N   . PRO C 1 239 ? -2.263  28.678  -17.790  1.00 58.36  ? 239 PRO C N   1 
ATOM   5841  C CA  . PRO C 1 239 ? -1.147  29.516  -17.338  1.00 52.16  ? 239 PRO C CA  1 
ATOM   5842  C C   . PRO C 1 239 ? -1.620  30.901  -16.925  1.00 53.54  ? 239 PRO C C   1 
ATOM   5843  O O   . PRO C 1 239 ? -2.503  31.489  -17.554  1.00 51.10  ? 239 PRO C O   1 
ATOM   5844  C CB  . PRO C 1 239 ? -0.229  29.572  -18.564  1.00 51.42  ? 239 PRO C CB  1 
ATOM   5845  C CG  . PRO C 1 239 ? -0.542  28.331  -19.325  1.00 47.23  ? 239 PRO C CG  1 
ATOM   5846  C CD  . PRO C 1 239 ? -2.006  28.081  -19.114  1.00 49.81  ? 239 PRO C CD  1 
ATOM   5847  N N   . ASN C 1 240 ? -1.020  31.410  -15.848  1.00 48.86  ? 240 ASN C N   1 
ATOM   5848  C CA  . ASN C 1 240 ? -1.289  32.709  -15.233  1.00 54.10  ? 240 ASN C CA  1 
ATOM   5849  C C   . ASN C 1 240 ? -2.653  32.781  -14.560  1.00 50.33  ? 240 ASN C C   1 
ATOM   5850  O O   . ASN C 1 240 ? -3.031  33.855  -14.076  1.00 58.37  ? 240 ASN C O   1 
ATOM   5851  C CB  . ASN C 1 240 ? -1.151  33.872  -16.224  1.00 57.41  ? 240 ASN C CB  1 
ATOM   5852  C CG  . ASN C 1 240 ? 0.293   34.197  -16.533  1.00 73.60  ? 240 ASN C CG  1 
ATOM   5853  O OD1 . ASN C 1 240 ? 1.119   34.340  -15.631  1.00 73.31  ? 240 ASN C OD1 1 
ATOM   5854  N ND2 . ASN C 1 240 ? 0.611   34.298  -17.820  1.00 76.87  ? 240 ASN C ND2 1 
ATOM   5855  N N   . ASP C 1 241 ? -3.406  31.689  -14.518  1.00 50.30  ? 241 ASP C N   1 
ATOM   5856  C CA  . ASP C 1 241 ? -4.589  31.599  -13.678  1.00 45.49  ? 241 ASP C CA  1 
ATOM   5857  C C   . ASP C 1 241 ? -4.199  31.021  -12.322  1.00 51.01  ? 241 ASP C C   1 
ATOM   5858  O O   . ASP C 1 241 ? -3.151  30.388  -12.170  1.00 49.24  ? 241 ASP C O   1 
ATOM   5859  C CB  . ASP C 1 241 ? -5.666  30.729  -14.334  1.00 52.00  ? 241 ASP C CB  1 
ATOM   5860  C CG  . ASP C 1 241 ? -7.028  30.892  -13.679  1.00 60.04  ? 241 ASP C CG  1 
ATOM   5861  O OD1 . ASP C 1 241 ? -7.206  31.862  -12.911  1.00 57.27  ? 241 ASP C OD1 1 
ATOM   5862  O OD2 . ASP C 1 241 ? -7.917  30.048  -13.928  1.00 59.75  ? 241 ASP C OD2 1 
ATOM   5863  N N   . ALA C 1 242 ? -5.052  31.252  -11.329  1.00 38.79  ? 242 ALA C N   1 
ATOM   5864  C CA  . ALA C 1 242 ? -4.834  30.724  -9.992   1.00 46.07  ? 242 ALA C CA  1 
ATOM   5865  C C   . ALA C 1 242 ? -6.048  29.926  -9.541   1.00 48.92  ? 242 ALA C C   1 
ATOM   5866  O O   . ALA C 1 242 ? -7.183  30.210  -9.936   1.00 46.58  ? 242 ALA C O   1 
ATOM   5867  C CB  . ALA C 1 242 ? -4.549  31.842  -8.978   1.00 43.22  ? 242 ALA C CB  1 
ATOM   5868  N N   . ILE C 1 243 ? -5.794  28.920  -8.710   1.00 45.53  ? 243 ILE C N   1 
ATOM   5869  C CA  . ILE C 1 243 ? -6.839  28.105  -8.105   1.00 44.03  ? 243 ILE C CA  1 
ATOM   5870  C C   . ILE C 1 243 ? -6.901  28.446  -6.622   1.00 47.44  ? 243 ILE C C   1 
ATOM   5871  O O   . ILE C 1 243 ? -5.865  28.603  -5.968   1.00 46.06  ? 243 ILE C O   1 
ATOM   5872  C CB  . ILE C 1 243 ? -6.588  26.600  -8.335   1.00 47.86  ? 243 ILE C CB  1 
ATOM   5873  C CG1 . ILE C 1 243 ? -7.689  25.761  -7.681   1.00 40.03  ? 243 ILE C CG1 1 
ATOM   5874  C CG2 . ILE C 1 243 ? -5.207  26.189  -7.832   1.00 34.98  ? 243 ILE C CG2 1 
ATOM   5875  C CD1 . ILE C 1 243 ? -7.788  24.359  -8.243   1.00 42.72  ? 243 ILE C CD1 1 
ATOM   5876  N N   . HIS C 1 244 ? -8.118  28.591  -6.100   1.00 41.52  ? 244 HIS C N   1 
ATOM   5877  C CA  . HIS C 1 244 ? -8.336  29.050  -4.733   1.00 41.55  ? 244 HIS C CA  1 
ATOM   5878  C C   . HIS C 1 244 ? -9.105  27.988  -3.960   1.00 49.97  ? 244 HIS C C   1 
ATOM   5879  O O   . HIS C 1 244 ? -10.220 27.622  -4.345   1.00 50.59  ? 244 HIS C O   1 
ATOM   5880  C CB  . HIS C 1 244 ? -9.089  30.381  -4.731   1.00 40.63  ? 244 HIS C CB  1 
ATOM   5881  C CG  . HIS C 1 244 ? -8.550  31.374  -5.713   1.00 45.41  ? 244 HIS C CG  1 
ATOM   5882  N ND1 . HIS C 1 244 ? -7.534  32.252  -5.404   1.00 46.81  ? 244 HIS C ND1 1 
ATOM   5883  C CD2 . HIS C 1 244 ? -8.876  31.615  -7.005   1.00 45.70  ? 244 HIS C CD2 1 
ATOM   5884  C CE1 . HIS C 1 244 ? -7.263  32.997  -6.461   1.00 41.64  ? 244 HIS C CE1 1 
ATOM   5885  N NE2 . HIS C 1 244 ? -8.063  32.631  -7.446   1.00 45.37  ? 244 HIS C NE2 1 
ATOM   5886  N N   . PHE C 1 245 ? -8.513  27.506  -2.870   1.00 38.74  ? 245 PHE C N   1 
ATOM   5887  C CA  . PHE C 1 245 ? -9.113  26.485  -2.023   1.00 39.10  ? 245 PHE C CA  1 
ATOM   5888  C C   . PHE C 1 245 ? -9.549  27.093  -0.698   1.00 39.97  ? 245 PHE C C   1 
ATOM   5889  O O   . PHE C 1 245 ? -8.820  27.891  -0.101   1.00 44.26  ? 245 PHE C O   1 
ATOM   5890  C CB  . PHE C 1 245 ? -8.131  25.342  -1.743   1.00 41.62  ? 245 PHE C CB  1 
ATOM   5891  C CG  . PHE C 1 245 ? -7.825  24.483  -2.934   1.00 42.30  ? 245 PHE C CG  1 
ATOM   5892  C CD1 . PHE C 1 245 ? -8.715  23.508  -3.351   1.00 50.15  ? 245 PHE C CD1 1 
ATOM   5893  C CD2 . PHE C 1 245 ? -6.631  24.631  -3.620   1.00 39.20  ? 245 PHE C CD2 1 
ATOM   5894  C CE1 . PHE C 1 245 ? -8.424  22.706  -4.439   1.00 48.62  ? 245 PHE C CE1 1 
ATOM   5895  C CE2 . PHE C 1 245 ? -6.337  23.835  -4.707   1.00 38.29  ? 245 PHE C CE2 1 
ATOM   5896  C CZ  . PHE C 1 245 ? -7.235  22.870  -5.116   1.00 42.50  ? 245 PHE C CZ  1 
ATOM   5897  N N   . GLU C 1 246 ? -10.737 26.708  -0.236   1.00 44.23  ? 246 GLU C N   1 
ATOM   5898  C CA  . GLU C 1 246 ? -11.183 27.040  1.109    1.00 49.71  ? 246 GLU C CA  1 
ATOM   5899  C C   . GLU C 1 246 ? -11.927 25.850  1.694    1.00 37.48  ? 246 GLU C C   1 
ATOM   5900  O O   . GLU C 1 246 ? -12.761 25.242  1.016    1.00 49.72  ? 246 GLU C O   1 
ATOM   5901  C CB  . GLU C 1 246 ? -12.074 28.287  1.122    1.00 47.30  ? 246 GLU C CB  1 
ATOM   5902  C CG  . GLU C 1 246 ? -12.451 28.752  2.522    1.00 48.12  ? 246 GLU C CG  1 
ATOM   5903  C CD  . GLU C 1 246 ? -13.108 30.119  2.529    1.00 65.83  ? 246 GLU C CD  1 
ATOM   5904  O OE1 . GLU C 1 246 ? -12.826 30.919  1.611    1.00 68.67  ? 246 GLU C OE1 1 
ATOM   5905  O OE2 . GLU C 1 246 ? -13.910 30.390  3.448    1.00 59.62  ? 246 GLU C OE2 1 
ATOM   5906  N N   . SER C 1 247 ? -11.622 25.517  2.946    1.00 43.58  ? 247 SER C N   1 
ATOM   5907  C CA  . SER C 1 247 ? -12.262 24.383  3.597    1.00 44.21  ? 247 SER C CA  1 
ATOM   5908  C C   . SER C 1 247 ? -12.058 24.472  5.101    1.00 48.69  ? 247 SER C C   1 
ATOM   5909  O O   . SER C 1 247 ? -11.026 24.956  5.574    1.00 44.98  ? 247 SER C O   1 
ATOM   5910  C CB  . SER C 1 247 ? -11.711 23.050  3.081    1.00 43.63  ? 247 SER C CB  1 
ATOM   5911  O OG  . SER C 1 247 ? -12.209 21.971  3.856    1.00 44.55  ? 247 SER C OG  1 
ATOM   5912  N N   . ASN C 1 248 ? -13.055 23.991  5.846    1.00 43.18  ? 248 ASN C N   1 
ATOM   5913  C CA  . ASN C 1 248 ? -12.933 23.800  7.286    1.00 49.70  ? 248 ASN C CA  1 
ATOM   5914  C C   . ASN C 1 248 ? -13.079 22.332  7.670    1.00 46.58  ? 248 ASN C C   1 
ATOM   5915  O O   . ASN C 1 248 ? -13.450 22.025  8.808    1.00 48.98  ? 248 ASN C O   1 
ATOM   5916  C CB  . ASN C 1 248 ? -13.954 24.656  8.039    1.00 43.80  ? 248 ASN C CB  1 
ATOM   5917  C CG  . ASN C 1 248 ? -15.381 24.239  7.763    1.00 52.89  ? 248 ASN C CG  1 
ATOM   5918  O OD1 . ASN C 1 248 ? -15.696 23.741  6.683    1.00 48.11  ? 248 ASN C OD1 1 
ATOM   5919  N ND2 . ASN C 1 248 ? -16.257 24.441  8.743    1.00 51.31  ? 248 ASN C ND2 1 
ATOM   5920  N N   . GLY C 1 249 ? -12.801 21.422  6.749    1.00 39.48  ? 249 GLY C N   1 
ATOM   5921  C CA  . GLY C 1 249 ? -12.824 20.009  7.068    1.00 45.44  ? 249 GLY C CA  1 
ATOM   5922  C C   . GLY C 1 249 ? -13.052 19.159  5.842    1.00 44.69  ? 249 GLY C C   1 
ATOM   5923  O O   . GLY C 1 249 ? -13.542 19.617  4.810    1.00 43.17  ? 249 GLY C O   1 
ATOM   5924  N N   . ASN C 1 250 ? -12.677 17.884  5.973    1.00 43.46  ? 250 ASN C N   1 
ATOM   5925  C CA  . ASN C 1 250 ? -12.924 16.844  4.976    1.00 46.81  ? 250 ASN C CA  1 
ATOM   5926  C C   . ASN C 1 250 ? -12.212 17.109  3.656    1.00 51.65  ? 250 ASN C C   1 
ATOM   5927  O O   . ASN C 1 250 ? -12.642 16.614  2.609    1.00 45.76  ? 250 ASN C O   1 
ATOM   5928  C CB  . ASN C 1 250 ? -14.426 16.662  4.731    1.00 40.96  ? 250 ASN C CB  1 
ATOM   5929  C CG  . ASN C 1 250 ? -15.200 16.444  6.011    1.00 41.85  ? 250 ASN C CG  1 
ATOM   5930  O OD1 . ASN C 1 250 ? -15.288 17.339  6.852    1.00 44.12  ? 250 ASN C OD1 1 
ATOM   5931  N ND2 . ASN C 1 250 ? -15.778 15.260  6.162    1.00 55.86  ? 250 ASN C ND2 1 
ATOM   5932  N N   . PHE C 1 251 ? -11.121 17.866  3.680    1.00 48.58  ? 251 PHE C N   1 
ATOM   5933  C CA  . PHE C 1 251 ? -10.453 18.312  2.465    1.00 48.19  ? 251 PHE C CA  1 
ATOM   5934  C C   . PHE C 1 251 ? -9.246  17.424  2.178    1.00 43.99  ? 251 PHE C C   1 
ATOM   5935  O O   . PHE C 1 251 ? -8.351  17.291  3.019    1.00 41.25  ? 251 PHE C O   1 
ATOM   5936  C CB  . PHE C 1 251 ? -10.032 19.776  2.600    1.00 38.01  ? 251 PHE C CB  1 
ATOM   5937  C CG  . PHE C 1 251 ? -9.356  20.329  1.381    1.00 43.43  ? 251 PHE C CG  1 
ATOM   5938  C CD1 . PHE C 1 251 ? -9.810  20.007  0.113    1.00 41.63  ? 251 PHE C CD1 1 
ATOM   5939  C CD2 . PHE C 1 251 ? -8.275  21.185  1.503    1.00 41.80  ? 251 PHE C CD2 1 
ATOM   5940  C CE1 . PHE C 1 251 ? -9.191  20.520  -1.009   1.00 48.72  ? 251 PHE C CE1 1 
ATOM   5941  C CE2 . PHE C 1 251 ? -7.654  21.701  0.383    1.00 45.90  ? 251 PHE C CE2 1 
ATOM   5942  C CZ  . PHE C 1 251 ? -8.112  21.367  -0.872   1.00 45.47  ? 251 PHE C CZ  1 
ATOM   5943  N N   . ILE C 1 252 ? -9.225  16.822  0.993    1.00 45.34  ? 252 ILE C N   1 
ATOM   5944  C CA  . ILE C 1 252 ? -8.067  16.082  0.503    1.00 37.38  ? 252 ILE C CA  1 
ATOM   5945  C C   . ILE C 1 252 ? -7.325  17.029  -0.433   1.00 42.07  ? 252 ILE C C   1 
ATOM   5946  O O   . ILE C 1 252 ? -7.700  17.199  -1.597   1.00 45.14  ? 252 ILE C O   1 
ATOM   5947  C CB  . ILE C 1 252 ? -8.468  14.780  -0.194   1.00 44.36  ? 252 ILE C CB  1 
ATOM   5948  C CG1 . ILE C 1 252 ? -9.568  14.067  0.593    1.00 45.62  ? 252 ILE C CG1 1 
ATOM   5949  C CG2 . ILE C 1 252 ? -7.263  13.867  -0.328   1.00 39.44  ? 252 ILE C CG2 1 
ATOM   5950  C CD1 . ILE C 1 252 ? -9.116  13.538  1.932    1.00 44.46  ? 252 ILE C CD1 1 
ATOM   5951  N N   . ALA C 1 253 ? -6.274  17.657  0.083    1.00 45.82  ? 253 ALA C N   1 
ATOM   5952  C CA  . ALA C 1 253 ? -5.604  18.744  -0.606   1.00 49.88  ? 253 ALA C CA  1 
ATOM   5953  C C   . ALA C 1 253 ? -4.648  18.223  -1.676   1.00 41.44  ? 253 ALA C C   1 
ATOM   5954  O O   . ALA C 1 253 ? -4.095  17.129  -1.548   1.00 48.13  ? 253 ALA C O   1 
ATOM   5955  C CB  . ALA C 1 253 ? -4.832  19.602  0.391    1.00 44.46  ? 253 ALA C CB  1 
ATOM   5956  N N   . PRO C 1 254 ? -4.439  18.992  -2.741   1.00 49.48  ? 254 PRO C N   1 
ATOM   5957  C CA  . PRO C 1 254 ? -3.384  18.642  -3.697   1.00 51.57  ? 254 PRO C CA  1 
ATOM   5958  C C   . PRO C 1 254 ? -2.009  18.947  -3.128   1.00 54.98  ? 254 PRO C C   1 
ATOM   5959  O O   . PRO C 1 254 ? -1.817  19.926  -2.403   1.00 58.03  ? 254 PRO C O   1 
ATOM   5960  C CB  . PRO C 1 254 ? -3.688  19.531  -4.912   1.00 44.87  ? 254 PRO C CB  1 
ATOM   5961  C CG  . PRO C 1 254 ? -5.063  20.090  -4.675   1.00 53.95  ? 254 PRO C CG  1 
ATOM   5962  C CD  . PRO C 1 254 ? -5.234  20.143  -3.192   1.00 49.46  ? 254 PRO C CD  1 
ATOM   5963  N N   . GLU C 1 255 ? -1.052  18.091  -3.452   1.00 54.59  ? 255 GLU C N   1 
ATOM   5964  C CA  . GLU C 1 255 ? 0.358   18.402  -3.265   1.00 47.50  ? 255 GLU C CA  1 
ATOM   5965  C C   . GLU C 1 255 ? 1.115   18.442  -4.577   1.00 54.37  ? 255 GLU C C   1 
ATOM   5966  O O   . GLU C 1 255 ? 1.921   19.350  -4.795   1.00 50.01  ? 255 GLU C O   1 
ATOM   5967  C CB  . GLU C 1 255 ? 1.027   17.386  -2.326   1.00 51.99  ? 255 GLU C CB  1 
ATOM   5968  C CG  . GLU C 1 255 ? 2.529   17.612  -2.183   1.00 69.61  ? 255 GLU C CG  1 
ATOM   5969  C CD  . GLU C 1 255 ? 3.180   16.693  -1.171   1.00 80.72  ? 255 GLU C CD  1 
ATOM   5970  O OE1 . GLU C 1 255 ? 2.474   15.834  -0.600   1.00 86.64  ? 255 GLU C OE1 1 
ATOM   5971  O OE2 . GLU C 1 255 ? 4.403   16.833  -0.946   1.00 68.00  ? 255 GLU C OE2 1 
ATOM   5972  N N   . TYR C 1 256 ? 0.862   17.486  -5.464   1.00 52.88  ? 256 TYR C N   1 
ATOM   5973  C CA  . TYR C 1 256 ? 1.456   17.454  -6.787   1.00 46.49  ? 256 TYR C CA  1 
ATOM   5974  C C   . TYR C 1 256 ? 0.387   17.705  -7.842   1.00 56.93  ? 256 TYR C C   1 
ATOM   5975  O O   . TYR C 1 256 ? -0.777  17.327  -7.677   1.00 69.16  ? 256 TYR C O   1 
ATOM   5976  C CB  . TYR C 1 256 ? 2.141   16.110  -7.057   1.00 42.29  ? 256 TYR C CB  1 
ATOM   5977  C CG  . TYR C 1 256 ? 3.273   15.793  -6.108   1.00 54.62  ? 256 TYR C CG  1 
ATOM   5978  C CD1 . TYR C 1 256 ? 4.572   16.201  -6.385   1.00 48.30  ? 256 TYR C CD1 1 
ATOM   5979  C CD2 . TYR C 1 256 ? 3.044   15.083  -4.935   1.00 57.13  ? 256 TYR C CD2 1 
ATOM   5980  C CE1 . TYR C 1 256 ? 5.611   15.912  -5.520   1.00 62.51  ? 256 TYR C CE1 1 
ATOM   5981  C CE2 . TYR C 1 256 ? 4.078   14.789  -4.063   1.00 46.94  ? 256 TYR C CE2 1 
ATOM   5982  C CZ  . TYR C 1 256 ? 5.359   15.205  -4.361   1.00 57.31  ? 256 TYR C CZ  1 
ATOM   5983  O OH  . TYR C 1 256 ? 6.392   14.916  -3.499   1.00 72.88  ? 256 TYR C OH  1 
ATOM   5984  N N   . ALA C 1 257 ? 0.794   18.365  -8.920   1.00 57.55  ? 257 ALA C N   1 
ATOM   5985  C CA  . ALA C 1 257 ? -0.019  18.539  -10.113  1.00 54.18  ? 257 ALA C CA  1 
ATOM   5986  C C   . ALA C 1 257 ? 0.788   18.050  -11.307  1.00 44.92  ? 257 ALA C C   1 
ATOM   5987  O O   . ALA C 1 257 ? 1.908   17.553  -11.161  1.00 46.52  ? 257 ALA C O   1 
ATOM   5988  C CB  . ALA C 1 257 ? -0.454  19.999  -10.289  1.00 47.12  ? 257 ALA C CB  1 
ATOM   5989  N N   . TYR C 1 258 ? 0.221   18.189  -12.502  1.00 48.75  ? 258 TYR C N   1 
ATOM   5990  C CA  . TYR C 1 258 ? 0.852   17.691  -13.717  1.00 51.25  ? 258 TYR C CA  1 
ATOM   5991  C C   . TYR C 1 258 ? 0.837   18.775  -14.780  1.00 46.28  ? 258 TYR C C   1 
ATOM   5992  O O   . TYR C 1 258 ? -0.238  19.206  -15.211  1.00 54.58  ? 258 TYR C O   1 
ATOM   5993  C CB  . TYR C 1 258 ? 0.142   16.439  -14.239  1.00 38.15  ? 258 TYR C CB  1 
ATOM   5994  C CG  . TYR C 1 258 ? 0.134   15.270  -13.279  1.00 57.43  ? 258 TYR C CG  1 
ATOM   5995  C CD1 . TYR C 1 258 ? 1.185   14.358  -13.255  1.00 51.11  ? 258 TYR C CD1 1 
ATOM   5996  C CD2 . TYR C 1 258 ? -0.928  15.069  -12.406  1.00 52.34  ? 258 TYR C CD2 1 
ATOM   5997  C CE1 . TYR C 1 258 ? 1.178   13.281  -12.389  1.00 60.64  ? 258 TYR C CE1 1 
ATOM   5998  C CE2 . TYR C 1 258 ? -0.943  13.996  -11.534  1.00 53.91  ? 258 TYR C CE2 1 
ATOM   5999  C CZ  . TYR C 1 258 ? 0.112   13.106  -11.530  1.00 59.31  ? 258 TYR C CZ  1 
ATOM   6000  O OH  . TYR C 1 258 ? 0.100   12.037  -10.667  1.00 53.76  ? 258 TYR C OH  1 
ATOM   6001  N N   . LYS C 1 259 ? 2.021   19.214  -15.200  1.00 50.60  ? 259 LYS C N   1 
ATOM   6002  C CA  . LYS C 1 259 ? 2.129   19.984  -16.431  1.00 52.56  ? 259 LYS C CA  1 
ATOM   6003  C C   . LYS C 1 259 ? 1.755   19.086  -17.601  1.00 53.36  ? 259 LYS C C   1 
ATOM   6004  O O   . LYS C 1 259 ? 2.248   17.959  -17.712  1.00 52.68  ? 259 LYS C O   1 
ATOM   6005  C CB  . LYS C 1 259 ? 3.547   20.533  -16.599  1.00 52.21  ? 259 LYS C CB  1 
ATOM   6006  C CG  . LYS C 1 259 ? 3.874   21.675  -15.651  1.00 58.14  ? 259 LYS C CG  1 
ATOM   6007  C CD  . LYS C 1 259 ? 5.336   21.693  -15.246  1.00 64.35  ? 259 LYS C CD  1 
ATOM   6008  C CE  . LYS C 1 259 ? 6.234   22.138  -16.381  1.00 71.43  ? 259 LYS C CE  1 
ATOM   6009  N NZ  . LYS C 1 259 ? 7.642   22.300  -15.921  1.00 76.11  ? 259 LYS C NZ  1 
ATOM   6010  N N   . ILE C 1 260 ? 0.868   19.568  -18.464  1.00 46.68  ? 260 ILE C N   1 
ATOM   6011  C CA  . ILE C 1 260 ? 0.274   18.727  -19.496  1.00 51.26  ? 260 ILE C CA  1 
ATOM   6012  C C   . ILE C 1 260 ? 0.138   19.526  -20.786  1.00 49.78  ? 260 ILE C C   1 
ATOM   6013  O O   . ILE C 1 260 ? -0.378  20.650  -20.780  1.00 58.56  ? 260 ILE C O   1 
ATOM   6014  C CB  . ILE C 1 260 ? -1.086  18.164  -19.032  1.00 53.96  ? 260 ILE C CB  1 
ATOM   6015  C CG1 . ILE C 1 260 ? -1.760  17.355  -20.139  1.00 54.13  ? 260 ILE C CG1 1 
ATOM   6016  C CG2 . ILE C 1 260 ? -1.995  19.277  -18.517  1.00 48.69  ? 260 ILE C CG2 1 
ATOM   6017  C CD1 . ILE C 1 260 ? -3.048  16.703  -19.690  1.00 67.66  ? 260 ILE C CD1 1 
ATOM   6018  N N   . VAL C 1 261 A 0.622   18.957  -21.888  1.00 57.84  ? 260 VAL C N   1 
ATOM   6019  C CA  . VAL C 1 261 A 0.449   19.519  -23.222  1.00 48.99  ? 260 VAL C CA  1 
ATOM   6020  C C   . VAL C 1 261 A -0.199  18.455  -24.093  1.00 53.74  ? 260 VAL C C   1 
ATOM   6021  O O   . VAL C 1 261 A 0.306   17.330  -24.188  1.00 56.21  ? 260 VAL C O   1 
ATOM   6022  C CB  . VAL C 1 261 A 1.785   19.979  -23.835  1.00 54.11  ? 260 VAL C CB  1 
ATOM   6023  C CG1 . VAL C 1 261 A 1.534   20.975  -24.957  1.00 48.00  ? 260 VAL C CG1 1 
ATOM   6024  C CG2 . VAL C 1 261 A 2.689   20.576  -22.773  1.00 65.40  ? 260 VAL C CG2 1 
ATOM   6025  N N   . LYS C 1 262 ? -1.313  18.808  -24.727  1.00 53.34  ? 261 LYS C N   1 
ATOM   6026  C CA  . LYS C 1 262 ? -2.053  17.889  -25.579  1.00 52.83  ? 261 LYS C CA  1 
ATOM   6027  C C   . LYS C 1 262 ? -2.104  18.453  -26.992  1.00 50.81  ? 261 LYS C C   1 
ATOM   6028  O O   . LYS C 1 262 ? -2.528  19.595  -27.193  1.00 48.86  ? 261 LYS C O   1 
ATOM   6029  C CB  . LYS C 1 262 ? -3.467  17.657  -25.039  1.00 57.08  ? 261 LYS C CB  1 
ATOM   6030  C CG  . LYS C 1 262 ? -4.229  16.550  -25.746  1.00 60.99  ? 261 LYS C CG  1 
ATOM   6031  C CD  . LYS C 1 262 ? -5.584  16.315  -25.102  1.00 64.73  ? 261 LYS C CD  1 
ATOM   6032  C CE  . LYS C 1 262 ? -6.383  15.267  -25.861  1.00 63.75  ? 261 LYS C CE  1 
ATOM   6033  N NZ  . LYS C 1 262 ? -5.686  13.950  -25.893  1.00 56.15  ? 261 LYS C NZ  1 
ATOM   6034  N N   . LYS C 1 263 ? -1.669  17.650  -27.963  1.00 55.96  ? 262 LYS C N   1 
ATOM   6035  C CA  . LYS C 1 263 ? -1.662  18.043  -29.366  1.00 64.48  ? 262 LYS C CA  1 
ATOM   6036  C C   . LYS C 1 263 ? -2.609  17.228  -30.231  1.00 68.65  ? 262 LYS C C   1 
ATOM   6037  O O   . LYS C 1 263 ? -3.081  17.734  -31.251  1.00 80.08  ? 262 LYS C O   1 
ATOM   6038  C CB  . LYS C 1 263 ? -0.246  17.919  -29.949  1.00 69.90  ? 262 LYS C CB  1 
ATOM   6039  C CG  . LYS C 1 263 ? 0.819   18.727  -29.226  1.00 72.09  ? 262 LYS C CG  1 
ATOM   6040  C CD  . LYS C 1 263 ? 0.742   20.203  -29.574  1.00 75.25  ? 262 LYS C CD  1 
ATOM   6041  C CE  . LYS C 1 263 ? 1.982   20.944  -29.091  1.00 74.02  ? 262 LYS C CE  1 
ATOM   6042  N NZ  . LYS C 1 263 ? 3.226   20.395  -29.706  1.00 85.50  ? 262 LYS C NZ  1 
ATOM   6043  N N   . GLY C 1 264 ? -2.895  15.981  -29.852  1.00 61.85  ? 263 GLY C N   1 
ATOM   6044  C CA  . GLY C 1 264 ? -3.751  15.115  -30.634  1.00 55.38  ? 263 GLY C CA  1 
ATOM   6045  C C   . GLY C 1 264 ? -4.633  14.269  -29.738  1.00 55.57  ? 263 GLY C C   1 
ATOM   6046  O O   . GLY C 1 264 ? -4.608  14.394  -28.512  1.00 58.28  ? 263 GLY C O   1 
ATOM   6047  N N   . ASP C 1 265 ? -5.406  13.393  -30.374  1.00 58.89  ? 264 ASP C N   1 
ATOM   6048  C CA  . ASP C 1 265 ? -6.396  12.581  -29.684  1.00 56.71  ? 264 ASP C CA  1 
ATOM   6049  C C   . ASP C 1 265 ? -6.166  11.105  -29.976  1.00 60.70  ? 264 ASP C C   1 
ATOM   6050  O O   . ASP C 1 265 ? -5.572  10.729  -30.989  1.00 56.86  ? 264 ASP C O   1 
ATOM   6051  C CB  . ASP C 1 265 ? -7.820  12.989  -30.082  1.00 60.29  ? 264 ASP C CB  1 
ATOM   6052  C CG  . ASP C 1 265 ? -8.235  14.316  -29.471  1.00 69.80  ? 264 ASP C CG  1 
ATOM   6053  O OD1 . ASP C 1 265 ? -8.423  14.371  -28.236  1.00 76.39  ? 264 ASP C OD1 1 
ATOM   6054  O OD2 . ASP C 1 265 ? -8.352  15.307  -30.221  1.00 82.24  ? 264 ASP C OD2 1 
ATOM   6055  N N   . SER C 1 266 ? -6.652  10.274  -29.061  1.00 50.86  ? 265 SER C N   1 
ATOM   6056  C CA  . SER C 1 266 ? -6.476  8.828   -29.104  1.00 54.28  ? 265 SER C CA  1 
ATOM   6057  C C   . SER C 1 266 ? -7.596  8.210   -28.270  1.00 45.98  ? 265 SER C C   1 
ATOM   6058  O O   . SER C 1 266 ? -8.619  8.856   -28.018  1.00 52.59  ? 265 SER C O   1 
ATOM   6059  C CB  . SER C 1 266 ? -5.073  8.438   -28.614  1.00 46.20  ? 265 SER C CB  1 
ATOM   6060  O OG  . SER C 1 266 ? -4.838  7.055   -28.793  1.00 51.53  ? 265 SER C OG  1 
ATOM   6061  N N   . THR C 1 267 ? -7.424  6.950   -27.875  1.00 46.42  ? 266 THR C N   1 
ATOM   6062  C CA  . THR C 1 267 ? -8.372  6.302   -26.980  1.00 55.30  ? 266 THR C CA  1 
ATOM   6063  C C   . THR C 1 267 ? -7.613  5.336   -26.080  1.00 47.16  ? 266 THR C C   1 
ATOM   6064  O O   . THR C 1 267 ? -6.393  5.180   -26.187  1.00 52.72  ? 266 THR C O   1 
ATOM   6065  C CB  . THR C 1 267 ? -9.481  5.588   -27.761  1.00 58.04  ? 266 THR C CB  1 
ATOM   6066  O OG1 . THR C 1 267 ? -10.574 5.298   -26.882  1.00 55.68  ? 266 THR C OG1 1 
ATOM   6067  C CG2 . THR C 1 267 ? -8.967  4.289   -28.355  1.00 48.38  ? 266 THR C CG2 1 
ATOM   6068  N N   . ILE C 1 268 ? -8.346  4.698   -25.172  1.00 52.95  ? 267 ILE C N   1 
ATOM   6069  C CA  . ILE C 1 268 ? -7.790  3.677   -24.293  1.00 52.02  ? 267 ILE C CA  1 
ATOM   6070  C C   . ILE C 1 268 ? -7.978  2.316   -24.950  1.00 66.41  ? 267 ILE C C   1 
ATOM   6071  O O   . ILE C 1 268 ? -9.082  1.973   -25.389  1.00 59.28  ? 267 ILE C O   1 
ATOM   6072  C CB  . ILE C 1 268 ? -8.454  3.716   -22.905  1.00 57.60  ? 267 ILE C CB  1 
ATOM   6073  C CG1 . ILE C 1 268 ? -7.887  4.858   -22.057  1.00 61.94  ? 267 ILE C CG1 1 
ATOM   6074  C CG2 . ILE C 1 268 ? -8.272  2.390   -22.184  1.00 59.87  ? 267 ILE C CG2 1 
ATOM   6075  C CD1 . ILE C 1 268 ? -8.504  6.207   -22.339  1.00 64.50  ? 267 ILE C CD1 1 
ATOM   6076  N N   . MET C 1 269 ? -6.899  1.544   -25.030  1.00 63.22  ? 268 MET C N   1 
ATOM   6077  C CA  . MET C 1 269 ? -6.948  0.185   -25.552  1.00 56.49  ? 268 MET C CA  1 
ATOM   6078  C C   . MET C 1 269 ? -6.927  -0.800  -24.392  1.00 58.41  ? 268 MET C C   1 
ATOM   6079  O O   . MET C 1 269 ? -6.099  -0.680  -23.483  1.00 56.81  ? 268 MET C O   1 
ATOM   6080  C CB  . MET C 1 269 ? -5.778  -0.085  -26.501  1.00 46.27  ? 268 MET C CB  1 
ATOM   6081  C CG  . MET C 1 269 ? -5.708  -1.521  -26.998  1.00 56.76  ? 268 MET C CG  1 
ATOM   6082  S SD  . MET C 1 269 ? -4.450  -1.782  -28.266  1.00 63.76  ? 268 MET C SD  1 
ATOM   6083  C CE  . MET C 1 269 ? -5.239  -1.043  -29.693  1.00 55.73  ? 268 MET C CE  1 
ATOM   6084  N N   . LYS C 1 270 ? -7.846  -1.761  -24.420  1.00 54.15  ? 269 LYS C N   1 
ATOM   6085  C CA  . LYS C 1 270 ? -7.937  -2.800  -23.401  1.00 59.93  ? 269 LYS C CA  1 
ATOM   6086  C C   . LYS C 1 270 ? -7.292  -4.066  -23.953  1.00 66.11  ? 269 LYS C C   1 
ATOM   6087  O O   . LYS C 1 270 ? -7.846  -4.713  -24.848  1.00 66.54  ? 269 LYS C O   1 
ATOM   6088  C CB  . LYS C 1 270 ? -9.391  -3.048  -23.005  1.00 62.92  ? 269 LYS C CB  1 
ATOM   6089  C CG  . LYS C 1 270 ? -10.058 -1.889  -22.278  1.00 58.11  ? 269 LYS C CG  1 
ATOM   6090  C CD  . LYS C 1 270 ? -9.455  -1.683  -20.896  1.00 68.92  ? 269 LYS C CD  1 
ATOM   6091  C CE  . LYS C 1 270 ? -10.311 -0.755  -20.045  1.00 61.41  ? 269 LYS C CE  1 
ATOM   6092  N NZ  . LYS C 1 270 ? -9.834  -0.708  -18.631  1.00 72.46  ? 269 LYS C NZ  1 
ATOM   6093  N N   . SER C 1 271 ? -6.123  -4.418  -23.422  1.00 61.58  ? 270 SER C N   1 
ATOM   6094  C CA  . SER C 1 271 ? -5.394  -5.581  -23.909  1.00 64.28  ? 270 SER C CA  1 
ATOM   6095  C C   . SER C 1 271 ? -4.437  -6.067  -22.831  1.00 67.40  ? 270 SER C C   1 
ATOM   6096  O O   . SER C 1 271 ? -4.077  -5.327  -21.911  1.00 63.23  ? 270 SER C O   1 
ATOM   6097  C CB  . SER C 1 271 ? -4.631  -5.260  -25.200  1.00 62.47  ? 270 SER C CB  1 
ATOM   6098  O OG  . SER C 1 271 ? -3.835  -6.357  -25.611  1.00 52.26  ? 270 SER C OG  1 
ATOM   6099  N N   . GLY C 1 272 ? -4.035  -7.329  -22.959  1.00 77.53  ? 271 GLY C N   1 
ATOM   6100  C CA  . GLY C 1 272 ? -3.037  -7.910  -22.082  1.00 68.09  ? 271 GLY C CA  1 
ATOM   6101  C C   . GLY C 1 272 ? -1.796  -8.327  -22.842  1.00 65.58  ? 271 GLY C C   1 
ATOM   6102  O O   . GLY C 1 272 ? -0.912  -8.993  -22.296  1.00 76.05  ? 271 GLY C O   1 
ATOM   6103  N N   . VAL C 1 273 ? -1.725  -7.934  -24.115  1.00 65.15  ? 272 VAL C N   1 
ATOM   6104  C CA  . VAL C 1 273 ? -0.607  -8.314  -24.969  1.00 74.83  ? 272 VAL C CA  1 
ATOM   6105  C C   . VAL C 1 273 ? 0.626   -7.496  -24.603  1.00 66.46  ? 272 VAL C C   1 
ATOM   6106  O O   . VAL C 1 273 ? 0.532   -6.310  -24.261  1.00 76.47  ? 272 VAL C O   1 
ATOM   6107  C CB  . VAL C 1 273 ? -0.993  -8.136  -26.448  1.00 59.81  ? 272 VAL C CB  1 
ATOM   6108  C CG1 . VAL C 1 273 ? 0.183   -8.439  -27.359  1.00 65.04  ? 272 VAL C CG1 1 
ATOM   6109  C CG2 . VAL C 1 273 ? -2.171  -9.034  -26.791  1.00 63.29  ? 272 VAL C CG2 1 
ATOM   6110  N N   . GLU C 1 274 ? 1.792   -8.135  -24.667  1.00 80.32  ? 273 GLU C N   1 
ATOM   6111  C CA  . GLU C 1 274 ? 3.042   -7.522  -24.242  1.00 74.49  ? 273 GLU C CA  1 
ATOM   6112  C C   . GLU C 1 274 ? 3.590   -6.563  -25.298  1.00 74.04  ? 273 GLU C C   1 
ATOM   6113  O O   . GLU C 1 274 ? 3.411   -6.756  -26.504  1.00 68.82  ? 273 GLU C O   1 
ATOM   6114  C CB  . GLU C 1 274 ? 4.076   -8.607  -23.923  1.00 88.38  ? 273 GLU C CB  1 
ATOM   6115  C CG  . GLU C 1 274 ? 5.502   -8.101  -23.756  1.00 102.18 ? 273 GLU C CG  1 
ATOM   6116  C CD  . GLU C 1 274 ? 6.276   -8.845  -22.690  1.00 108.14 ? 273 GLU C CD  1 
ATOM   6117  O OE1 . GLU C 1 274 ? 7.519   -8.911  -22.797  1.00 100.46 ? 273 GLU C OE1 1 
ATOM   6118  O OE2 . GLU C 1 274 ? 5.644   -9.357  -21.744  1.00 103.94 ? 273 GLU C OE2 1 
ATOM   6119  N N   . TYR C 1 275 ? 4.259   -5.513  -24.820  1.00 79.08  ? 274 TYR C N   1 
ATOM   6120  C CA  . TYR C 1 275 ? 4.950   -4.572  -25.693  1.00 78.06  ? 274 TYR C CA  1 
ATOM   6121  C C   . TYR C 1 275 ? 6.041   -5.280  -26.491  1.00 77.03  ? 274 TYR C C   1 
ATOM   6122  O O   . TYR C 1 275 ? 6.697   -6.198  -25.994  1.00 74.16  ? 274 TYR C O   1 
ATOM   6123  C CB  . TYR C 1 275 ? 5.548   -3.445  -24.849  1.00 68.93  ? 274 TYR C CB  1 
ATOM   6124  C CG  . TYR C 1 275 ? 6.265   -2.376  -25.635  1.00 68.70  ? 274 TYR C CG  1 
ATOM   6125  C CD1 . TYR C 1 275 ? 5.558   -1.468  -26.409  1.00 67.37  ? 274 TYR C CD1 1 
ATOM   6126  C CD2 . TYR C 1 275 ? 7.647   -2.261  -25.586  1.00 71.17  ? 274 TYR C CD2 1 
ATOM   6127  C CE1 . TYR C 1 275 ? 6.207   -0.484  -27.125  1.00 72.16  ? 274 TYR C CE1 1 
ATOM   6128  C CE2 . TYR C 1 275 ? 8.308   -1.278  -26.298  1.00 72.50  ? 274 TYR C CE2 1 
ATOM   6129  C CZ  . TYR C 1 275 ? 7.583   -0.392  -27.066  1.00 81.00  ? 274 TYR C CZ  1 
ATOM   6130  O OH  . TYR C 1 275 ? 8.234   0.589   -27.778  1.00 70.24  ? 274 TYR C OH  1 
ATOM   6131  N N   . GLY C 1 276 ? 6.239   -4.848  -27.738  1.00 72.53  ? 275 GLY C N   1 
ATOM   6132  C CA  . GLY C 1 276 ? 7.090   -5.599  -28.642  1.00 75.21  ? 275 GLY C CA  1 
ATOM   6133  C C   . GLY C 1 276 ? 8.268   -4.883  -29.275  1.00 79.58  ? 275 GLY C C   1 
ATOM   6134  O O   . GLY C 1 276 ? 8.957   -5.470  -30.115  1.00 85.62  ? 275 GLY C O   1 
ATOM   6135  N N   . HIS C 1 277 ? 8.519   -3.632  -28.890  1.00 79.62  ? 276 HIS C N   1 
ATOM   6136  C CA  . HIS C 1 277 ? 9.637   -2.847  -29.425  1.00 88.80  ? 276 HIS C CA  1 
ATOM   6137  C C   . HIS C 1 277 ? 9.571   -2.771  -30.951  1.00 79.08  ? 276 HIS C C   1 
ATOM   6138  O O   . HIS C 1 277 ? 10.557  -2.990  -31.662  1.00 89.44  ? 276 HIS C O   1 
ATOM   6139  C CB  . HIS C 1 277 ? 10.980  -3.407  -28.958  1.00 81.77  ? 276 HIS C CB  1 
ATOM   6140  C CG  . HIS C 1 277 ? 11.137  -3.449  -27.468  1.00 92.06  ? 276 HIS C CG  1 
ATOM   6141  N ND1 . HIS C 1 277 ? 11.551  -2.360  -26.730  1.00 96.59  ? 276 HIS C ND1 1 
ATOM   6142  C CD2 . HIS C 1 277 ? 10.949  -4.454  -26.579  1.00 84.54  ? 276 HIS C CD2 1 
ATOM   6143  C CE1 . HIS C 1 277 ? 11.606  -2.691  -25.452  1.00 95.67  ? 276 HIS C CE1 1 
ATOM   6144  N NE2 . HIS C 1 277 ? 11.245  -3.957  -25.333  1.00 96.81  ? 276 HIS C NE2 1 
ATOM   6145  N N   . CYS C 1 278 ? 8.384   -2.439  -31.450  1.00 86.49  ? 277 CYS C N   1 
ATOM   6146  C CA  . CYS C 1 278 ? 8.107   -2.343  -32.876  1.00 74.71  ? 277 CYS C CA  1 
ATOM   6147  C C   . CYS C 1 278 ? 7.546   -0.956  -33.171  1.00 74.62  ? 277 CYS C C   1 
ATOM   6148  O O   . CYS C 1 278 ? 7.423   -0.106  -32.282  1.00 81.99  ? 277 CYS C O   1 
ATOM   6149  C CB  . CYS C 1 278 ? 7.139   -3.450  -33.322  1.00 71.85  ? 277 CYS C CB  1 
ATOM   6150  S SG  . CYS C 1 278 ? 5.938   -3.928  -32.067  1.00 112.68 ? 277 CYS C SG  1 
ATOM   6151  N N   . ASN C 1 279 ? 7.219   -0.723  -34.438  1.00 58.89  ? 278 ASN C N   1 
ATOM   6152  C CA  . ASN C 1 279 ? 6.557   0.500   -34.863  1.00 66.53  ? 278 ASN C CA  1 
ATOM   6153  C C   . ASN C 1 279 ? 5.455   0.141   -35.848  1.00 77.97  ? 278 ASN C C   1 
ATOM   6154  O O   . ASN C 1 279 ? 5.593   -0.796  -36.638  1.00 84.24  ? 278 ASN C O   1 
ATOM   6155  C CB  . ASN C 1 279 ? 7.539   1.489   -35.506  1.00 69.33  ? 278 ASN C CB  1 
ATOM   6156  C CG  . ASN C 1 279 ? 6.944   2.870   -35.667  1.00 76.21  ? 278 ASN C CG  1 
ATOM   6157  O OD1 . ASN C 1 279 ? 6.010   3.239   -34.957  1.00 76.41  ? 278 ASN C OD1 1 
ATOM   6158  N ND2 . ASN C 1 279 ? 7.483   3.644   -36.602  1.00 81.87  ? 278 ASN C ND2 1 
ATOM   6159  N N   . THR C 1 280 ? 4.357   0.893   -35.794  1.00 72.18  ? 279 THR C N   1 
ATOM   6160  C CA  . THR C 1 280 ? 3.214   0.616   -36.653  1.00 65.88  ? 279 THR C CA  1 
ATOM   6161  C C   . THR C 1 280 ? 2.415   1.890   -36.871  1.00 68.09  ? 279 THR C C   1 
ATOM   6162  O O   . THR C 1 280 ? 2.550   2.871   -36.135  1.00 72.05  ? 279 THR C O   1 
ATOM   6163  C CB  . THR C 1 280 ? 2.303   -0.469  -36.062  1.00 71.03  ? 279 THR C CB  1 
ATOM   6164  O OG1 . THR C 1 280 ? 1.271   -0.792  -37.002  1.00 69.02  ? 279 THR C OG1 1 
ATOM   6165  C CG2 . THR C 1 280 ? 1.660   0.019   -34.772  1.00 71.08  ? 279 THR C CG2 1 
ATOM   6166  N N   . LYS C 1 281 ? 1.586   1.863   -37.912  1.00 67.17  ? 280 LYS C N   1 
ATOM   6167  C CA  . LYS C 1 281 ? 0.591   2.895   -38.154  1.00 67.87  ? 280 LYS C CA  1 
ATOM   6168  C C   . LYS C 1 281 ? -0.810  2.456   -37.751  1.00 63.61  ? 280 LYS C C   1 
ATOM   6169  O O   . LYS C 1 281 ? -1.730  3.281   -37.767  1.00 56.77  ? 280 LYS C O   1 
ATOM   6170  C CB  . LYS C 1 281 ? 0.593   3.297   -39.635  1.00 70.00  ? 280 LYS C CB  1 
ATOM   6171  C CG  . LYS C 1 281 ? 0.202   2.164   -40.570  1.00 72.53  ? 280 LYS C CG  1 
ATOM   6172  C CD  . LYS C 1 281 ? 0.231   2.597   -42.028  1.00 86.62  ? 280 LYS C CD  1 
ATOM   6173  C CE  . LYS C 1 281 ? -0.047  1.421   -42.953  1.00 82.13  ? 280 LYS C CE  1 
ATOM   6174  N NZ  . LYS C 1 281 ? 0.067   1.795   -44.389  1.00 89.23  ? 280 LYS C NZ  1 
ATOM   6175  N N   . CYS C 1 282 ? -0.988  1.187   -37.387  1.00 54.23  ? 281 CYS C N   1 
ATOM   6176  C CA  . CYS C 1 282 ? -2.302  0.642   -37.061  1.00 57.64  ? 281 CYS C CA  1 
ATOM   6177  C C   . CYS C 1 282 ? -2.138  -0.410  -35.975  1.00 66.91  ? 281 CYS C C   1 
ATOM   6178  O O   . CYS C 1 282 ? -1.399  -1.381  -36.164  1.00 70.58  ? 281 CYS C O   1 
ATOM   6179  C CB  . CYS C 1 282 ? -2.964  0.041   -38.303  1.00 69.11  ? 281 CYS C CB  1 
ATOM   6180  S SG  . CYS C 1 282 ? -4.527  -0.789  -37.973  1.00 68.93  ? 281 CYS C SG  1 
ATOM   6181  N N   . GLN C 1 283 ? -2.830  -0.227  -34.851  1.00 64.81  ? 282 GLN C N   1 
ATOM   6182  C CA  . GLN C 1 283 ? -2.709  -1.104  -33.694  1.00 49.53  ? 282 GLN C CA  1 
ATOM   6183  C C   . GLN C 1 283 ? -4.074  -1.655  -33.300  1.00 64.37  ? 282 GLN C C   1 
ATOM   6184  O O   . GLN C 1 283 ? -5.077  -0.936  -33.329  1.00 56.55  ? 282 GLN C O   1 
ATOM   6185  C CB  . GLN C 1 283 ? -2.089  -0.361  -32.504  1.00 49.97  ? 282 GLN C CB  1 
ATOM   6186  C CG  . GLN C 1 283 ? -1.878  -1.222  -31.269  1.00 46.98  ? 282 GLN C CG  1 
ATOM   6187  C CD  . GLN C 1 283 ? -0.809  -2.280  -31.468  1.00 61.37  ? 282 GLN C CD  1 
ATOM   6188  O OE1 . GLN C 1 283 ? 0.338   -1.967  -31.787  1.00 61.46  ? 282 GLN C OE1 1 
ATOM   6189  N NE2 . GLN C 1 283 ? -1.182  -3.541  -31.285  1.00 54.86  ? 282 GLN C NE2 1 
ATOM   6190  N N   . THR C 1 284 ? -4.103  -2.932  -32.935  1.00 61.00  ? 283 THR C N   1 
ATOM   6191  C CA  . THR C 1 284 ? -5.280  -3.633  -32.446  1.00 59.93  ? 283 THR C CA  1 
ATOM   6192  C C   . THR C 1 284 ? -4.938  -4.277  -31.112  1.00 56.92  ? 283 THR C C   1 
ATOM   6193  O O   . THR C 1 284 ? -3.760  -4.455  -30.787  1.00 62.12  ? 283 THR C O   1 
ATOM   6194  C CB  . THR C 1 284 ? -5.759  -4.711  -33.434  1.00 58.28  ? 283 THR C CB  1 
ATOM   6195  O OG1 . THR C 1 284 ? -5.008  -5.915  -33.236  1.00 69.78  ? 283 THR C OG1 1 
ATOM   6196  C CG2 . THR C 1 284 ? -5.592  -4.248  -34.871  1.00 55.45  ? 283 THR C CG2 1 
ATOM   6197  N N   . PRO C 1 285 ? -5.946  -4.629  -30.305  1.00 60.52  ? 284 PRO C N   1 
ATOM   6198  C CA  . PRO C 1 285 ? -5.654  -5.273  -29.013  1.00 56.94  ? 284 PRO C CA  1 
ATOM   6199  C C   . PRO C 1 285 ? -4.930  -6.606  -29.131  1.00 58.65  ? 284 PRO C C   1 
ATOM   6200  O O   . PRO C 1 285 ? -4.376  -7.079  -28.129  1.00 59.73  ? 284 PRO C O   1 
ATOM   6201  C CB  . PRO C 1 285 ? -7.044  -5.452  -28.387  1.00 57.48  ? 284 PRO C CB  1 
ATOM   6202  C CG  . PRO C 1 285 ? -7.879  -4.406  -29.027  1.00 55.47  ? 284 PRO C CG  1 
ATOM   6203  C CD  . PRO C 1 285 ? -7.377  -4.302  -30.436  1.00 61.17  ? 284 PRO C CD  1 
ATOM   6204  N N   . VAL C 1 286 ? -4.926  -7.240  -30.306  1.00 53.36  ? 285 VAL C N   1 
ATOM   6205  C CA  . VAL C 1 286 ? -4.233  -8.515  -30.483  1.00 61.26  ? 285 VAL C CA  1 
ATOM   6206  C C   . VAL C 1 286 ? -2.928  -8.382  -31.260  1.00 59.75  ? 285 VAL C C   1 
ATOM   6207  O O   . VAL C 1 286 ? -2.162  -9.358  -31.330  1.00 69.19  ? 285 VAL C O   1 
ATOM   6208  C CB  . VAL C 1 286 ? -5.137  -9.556  -31.174  1.00 63.45  ? 285 VAL C CB  1 
ATOM   6209  C CG1 . VAL C 1 286 ? -6.328  -9.892  -30.292  1.00 56.48  ? 285 VAL C CG1 1 
ATOM   6210  C CG2 . VAL C 1 286 ? -5.594  -9.044  -32.531  1.00 57.17  ? 285 VAL C CG2 1 
ATOM   6211  N N   . GLY C 1 287 ? -2.648  -7.225  -31.842  1.00 62.11  ? 286 GLY C N   1 
ATOM   6212  C CA  . GLY C 1 287 ? -1.400  -7.033  -32.556  1.00 55.97  ? 286 GLY C CA  1 
ATOM   6213  C C   . GLY C 1 287 ? -1.508  -5.923  -33.573  1.00 55.85  ? 286 GLY C C   1 
ATOM   6214  O O   . GLY C 1 287 ? -2.592  -5.446  -33.906  1.00 54.85  ? 286 GLY C O   1 
ATOM   6215  N N   . ALA C 1 288 ? -0.344  -5.520  -34.075  1.00 56.33  ? 287 ALA C N   1 
ATOM   6216  C CA  . ALA C 1 288 ? -0.233  -4.434  -35.037  1.00 61.80  ? 287 ALA C CA  1 
ATOM   6217  C C   . ALA C 1 288 ? -0.397  -4.948  -36.464  1.00 67.57  ? 287 ALA C C   1 
ATOM   6218  O O   . ALA C 1 288 ? -0.171  -6.122  -36.760  1.00 58.16  ? 287 ALA C O   1 
ATOM   6219  C CB  . ALA C 1 288 ? 1.113   -3.725  -34.889  1.00 51.42  ? 287 ALA C CB  1 
ATOM   6220  N N   . ILE C 1 289 ? -0.781  -4.038  -37.357  1.00 63.67  ? 288 ILE C N   1 
ATOM   6221  C CA  . ILE C 1 289 ? -1.035  -4.352  -38.758  1.00 61.95  ? 288 ILE C CA  1 
ATOM   6222  C C   . ILE C 1 289 ? -0.095  -3.519  -39.620  1.00 70.76  ? 288 ILE C C   1 
ATOM   6223  O O   . ILE C 1 289 ? -0.036  -2.292  -39.478  1.00 69.42  ? 288 ILE C O   1 
ATOM   6224  C CB  . ILE C 1 289 ? -2.503  -4.088  -39.139  1.00 70.81  ? 288 ILE C CB  1 
ATOM   6225  C CG1 . ILE C 1 289 ? -3.427  -5.061  -38.407  1.00 72.21  ? 288 ILE C CG1 1 
ATOM   6226  C CG2 . ILE C 1 289 ? -2.693  -4.191  -40.644  1.00 71.03  ? 288 ILE C CG2 1 
ATOM   6227  C CD1 . ILE C 1 289 ? -4.897  -4.788  -38.636  1.00 72.73  ? 288 ILE C CD1 1 
ATOM   6228  N N   . ASN C 1 290 ? 0.631   -4.187  -40.513  1.00 62.45  ? 289 ASN C N   1 
ATOM   6229  C CA  . ASN C 1 290 ? 1.566   -3.550  -41.439  1.00 67.28  ? 289 ASN C CA  1 
ATOM   6230  C C   . ASN C 1 290 ? 1.122   -3.920  -42.852  1.00 80.43  ? 289 ASN C C   1 
ATOM   6231  O O   . ASN C 1 290 ? 1.569   -4.924  -43.412  1.00 82.32  ? 289 ASN C O   1 
ATOM   6232  C CB  . ASN C 1 290 ? 3.006   -3.997  -41.159  1.00 61.16  ? 289 ASN C CB  1 
ATOM   6233  C CG  . ASN C 1 290 ? 4.001   -3.430  -42.156  1.00 82.93  ? 289 ASN C CG  1 
ATOM   6234  O OD1 . ASN C 1 290 ? 3.775   -2.373  -42.745  1.00 81.71  ? 289 ASN C OD1 1 
ATOM   6235  N ND2 . ASN C 1 290 ? 5.111   -4.135  -42.350  1.00 85.08  ? 289 ASN C ND2 1 
ATOM   6236  N N   . SER C 1 291 ? 0.239   -3.108  -43.430  1.00 75.38  ? 290 SER C N   1 
ATOM   6237  C CA  . SER C 1 291 ? -0.351  -3.461  -44.713  1.00 76.33  ? 290 SER C CA  1 
ATOM   6238  C C   . SER C 1 291 ? -0.806  -2.206  -45.441  1.00 81.54  ? 290 SER C C   1 
ATOM   6239  O O   . SER C 1 291 ? -0.992  -1.145  -44.839  1.00 84.88  ? 290 SER C O   1 
ATOM   6240  C CB  . SER C 1 291 ? -1.529  -4.423  -44.533  1.00 85.04  ? 290 SER C CB  1 
ATOM   6241  O OG  . SER C 1 291 ? -2.197  -4.648  -45.760  1.00 78.20  ? 290 SER C OG  1 
ATOM   6242  N N   . SER C 1 292 ? -0.983  -2.352  -46.753  1.00 78.58  ? 291 SER C N   1 
ATOM   6243  C CA  . SER C 1 292 ? -1.582  -1.326  -47.594  1.00 62.88  ? 291 SER C CA  1 
ATOM   6244  C C   . SER C 1 292 ? -2.939  -1.744  -48.141  1.00 73.96  ? 291 SER C C   1 
ATOM   6245  O O   . SER C 1 292 ? -3.516  -1.015  -48.955  1.00 75.00  ? 291 SER C O   1 
ATOM   6246  C CB  . SER C 1 292 ? -0.643  -0.977  -48.755  1.00 68.28  ? 291 SER C CB  1 
ATOM   6247  O OG  . SER C 1 292 ? 0.618   -0.544  -48.278  1.00 89.42  ? 291 SER C OG  1 
ATOM   6248  N N   . MET C 1 293 ? -3.458  -2.895  -47.720  1.00 77.71  ? 292 MET C N   1 
ATOM   6249  C CA  . MET C 1 293 ? -4.734  -3.378  -48.219  1.00 72.71  ? 292 MET C CA  1 
ATOM   6250  C C   . MET C 1 293 ? -5.878  -2.501  -47.711  1.00 81.48  ? 292 MET C C   1 
ATOM   6251  O O   . MET C 1 293 ? -5.782  -1.896  -46.640  1.00 81.10  ? 292 MET C O   1 
ATOM   6252  C CB  . MET C 1 293 ? -4.959  -4.824  -47.786  1.00 69.61  ? 292 MET C CB  1 
ATOM   6253  C CG  . MET C 1 293 ? -3.885  -5.805  -48.244  1.00 79.57  ? 292 MET C CG  1 
ATOM   6254  S SD  . MET C 1 293 ? -3.912  -6.156  -50.016  1.00 87.50  ? 292 MET C SD  1 
ATOM   6255  C CE  . MET C 1 293 ? -2.711  -4.980  -50.638  1.00 68.82  ? 292 MET C CE  1 
ATOM   6256  N N   . PRO C 1 294 ? -6.974  -2.408  -48.471  1.00 76.42  ? 293 PRO C N   1 
ATOM   6257  C CA  . PRO C 1 294 ? -8.110  -1.588  -48.030  1.00 69.42  ? 293 PRO C CA  1 
ATOM   6258  C C   . PRO C 1 294 ? -9.030  -2.269  -47.028  1.00 67.34  ? 293 PRO C C   1 
ATOM   6259  O O   . PRO C 1 294 ? -9.874  -1.583  -46.434  1.00 69.90  ? 293 PRO C O   1 
ATOM   6260  C CB  . PRO C 1 294 ? -8.851  -1.296  -49.340  1.00 66.66  ? 293 PRO C CB  1 
ATOM   6261  C CG  . PRO C 1 294 ? -8.559  -2.480  -50.193  1.00 68.41  ? 293 PRO C CG  1 
ATOM   6262  C CD  . PRO C 1 294 ? -7.162  -2.926  -49.838  1.00 71.47  ? 293 PRO C CD  1 
ATOM   6263  N N   . PHE C 1 295 ? -8.906  -3.578  -46.815  1.00 60.58  ? 294 PHE C N   1 
ATOM   6264  C CA  . PHE C 1 295 ? -9.822  -4.295  -45.940  1.00 52.86  ? 294 PHE C CA  1 
ATOM   6265  C C   . PHE C 1 295 ? -9.051  -5.241  -45.030  1.00 60.54  ? 294 PHE C C   1 
ATOM   6266  O O   . PHE C 1 295 ? -7.957  -5.700  -45.366  1.00 69.74  ? 294 PHE C O   1 
ATOM   6267  C CB  . PHE C 1 295 ? -10.869 -5.077  -46.747  1.00 60.12  ? 294 PHE C CB  1 
ATOM   6268  C CG  . PHE C 1 295 ? -11.608 -4.238  -47.751  1.00 71.58  ? 294 PHE C CG  1 
ATOM   6269  C CD1 . PHE C 1 295 ? -12.586 -3.345  -47.344  1.00 66.57  ? 294 PHE C CD1 1 
ATOM   6270  C CD2 . PHE C 1 295 ? -11.324 -4.341  -49.103  1.00 67.17  ? 294 PHE C CD2 1 
ATOM   6271  C CE1 . PHE C 1 295 ? -13.265 -2.570  -48.266  1.00 63.51  ? 294 PHE C CE1 1 
ATOM   6272  C CE2 . PHE C 1 295 ? -11.999 -3.569  -50.029  1.00 70.59  ? 294 PHE C CE2 1 
ATOM   6273  C CZ  . PHE C 1 295 ? -12.971 -2.682  -49.610  1.00 70.91  ? 294 PHE C CZ  1 
ATOM   6274  N N   . HIS C 1 296 ? -9.638  -5.524  -43.867  1.00 55.46  ? 295 HIS C N   1 
ATOM   6275  C CA  . HIS C 1 296 ? -9.073  -6.472  -42.917  1.00 55.58  ? 295 HIS C CA  1 
ATOM   6276  C C   . HIS C 1 296 ? -10.201 -7.022  -42.057  1.00 54.20  ? 295 HIS C C   1 
ATOM   6277  O O   . HIS C 1 296 ? -11.298 -6.459  -42.007  1.00 66.48  ? 295 HIS C O   1 
ATOM   6278  C CB  . HIS C 1 296 ? -7.985  -5.830  -42.047  1.00 61.44  ? 295 HIS C CB  1 
ATOM   6279  C CG  . HIS C 1 296 ? -8.519  -5.012  -40.913  1.00 63.51  ? 295 HIS C CG  1 
ATOM   6280  N ND1 . HIS C 1 296 ? -8.786  -5.546  -39.670  1.00 68.94  ? 295 HIS C ND1 1 
ATOM   6281  C CD2 . HIS C 1 296 ? -8.834  -3.697  -40.833  1.00 61.82  ? 295 HIS C CD2 1 
ATOM   6282  C CE1 . HIS C 1 296 ? -9.243  -4.596  -38.874  1.00 56.97  ? 295 HIS C CE1 1 
ATOM   6283  N NE2 . HIS C 1 296 ? -9.283  -3.465  -39.555  1.00 54.14  ? 295 HIS C NE2 1 
ATOM   6284  N N   . ASN C 1 297 ? -9.918  -8.137  -41.381  1.00 54.69  ? 296 ASN C N   1 
ATOM   6285  C CA  . ASN C 1 297 ? -10.900 -8.812  -40.539  1.00 66.14  ? 296 ASN C CA  1 
ATOM   6286  C C   . ASN C 1 297 ? -10.311 -9.171  -39.180  1.00 67.42  ? 296 ASN C C   1 
ATOM   6287  O O   . ASN C 1 297 ? -10.759 -10.123 -38.535  1.00 63.33  ? 296 ASN C O   1 
ATOM   6288  C CB  . ASN C 1 297 ? -11.438 -10.065 -41.231  1.00 59.84  ? 296 ASN C CB  1 
ATOM   6289  C CG  . ASN C 1 297 ? -10.367 -11.123 -41.442  1.00 73.97  ? 296 ASN C CG  1 
ATOM   6290  O OD1 . ASN C 1 297 ? -9.171  -10.830 -41.402  1.00 77.39  ? 296 ASN C OD1 1 
ATOM   6291  N ND2 . ASN C 1 297 ? -10.795 -12.360 -41.674  1.00 72.92  ? 296 ASN C ND2 1 
ATOM   6292  N N   . ILE C 1 298 ? -9.315  -8.413  -38.726  1.00 67.71  ? 297 ILE C N   1 
ATOM   6293  C CA  . ILE C 1 298 ? -8.559  -8.807  -37.540  1.00 69.68  ? 297 ILE C CA  1 
ATOM   6294  C C   . ILE C 1 298 ? -9.286  -8.397  -36.264  1.00 67.91  ? 297 ILE C C   1 
ATOM   6295  O O   . ILE C 1 298 ? -9.560  -9.232  -35.393  1.00 69.48  ? 297 ILE C O   1 
ATOM   6296  C CB  . ILE C 1 298 ? -7.136  -8.223  -37.597  1.00 68.00  ? 297 ILE C CB  1 
ATOM   6297  C CG1 . ILE C 1 298 ? -6.368  -8.839  -38.769  1.00 59.69  ? 297 ILE C CG1 1 
ATOM   6298  C CG2 . ILE C 1 298 ? -6.410  -8.466  -36.285  1.00 60.51  ? 297 ILE C CG2 1 
ATOM   6299  C CD1 . ILE C 1 298 ? -4.926  -8.416  -38.849  1.00 61.56  ? 297 ILE C CD1 1 
ATOM   6300  N N   . HIS C 1 299 ? -9.605  -7.110  -36.129  1.00 62.48  ? 298 HIS C N   1 
ATOM   6301  C CA  . HIS C 1 299 ? -10.225 -6.610  -34.909  1.00 58.57  ? 298 HIS C CA  1 
ATOM   6302  C C   . HIS C 1 299 ? -10.886 -5.275  -35.210  1.00 56.11  ? 298 HIS C C   1 
ATOM   6303  O O   . HIS C 1 299 ? -10.377 -4.510  -36.037  1.00 54.57  ? 298 HIS C O   1 
ATOM   6304  C CB  . HIS C 1 299 ? -9.187  -6.453  -33.787  1.00 61.89  ? 298 HIS C CB  1 
ATOM   6305  C CG  . HIS C 1 299 ? -9.762  -6.567  -32.410  1.00 58.14  ? 298 HIS C CG  1 
ATOM   6306  N ND1 . HIS C 1 299 ? -10.425 -5.530  -31.790  1.00 56.73  ? 298 HIS C ND1 1 
ATOM   6307  C CD2 . HIS C 1 299 ? -9.766  -7.596  -31.529  1.00 57.55  ? 298 HIS C CD2 1 
ATOM   6308  C CE1 . HIS C 1 299 ? -10.819 -5.916  -30.589  1.00 54.21  ? 298 HIS C CE1 1 
ATOM   6309  N NE2 . HIS C 1 299 ? -10.432 -7.166  -30.406  1.00 46.63  ? 298 HIS C NE2 1 
ATOM   6310  N N   . PRO C 1 300 ? -12.020 -4.971  -34.576  1.00 54.69  ? 299 PRO C N   1 
ATOM   6311  C CA  . PRO C 1 300 ? -12.657 -3.664  -34.790  1.00 54.84  ? 299 PRO C CA  1 
ATOM   6312  C C   . PRO C 1 300 ? -12.025 -2.528  -33.996  1.00 55.77  ? 299 PRO C C   1 
ATOM   6313  O O   . PRO C 1 300 ? -12.056 -1.373  -34.433  1.00 65.55  ? 299 PRO C O   1 
ATOM   6314  C CB  . PRO C 1 300 ? -14.104 -3.910  -34.345  1.00 48.31  ? 299 PRO C CB  1 
ATOM   6315  C CG  . PRO C 1 300 ? -14.004 -5.020  -33.358  1.00 54.02  ? 299 PRO C CG  1 
ATOM   6316  C CD  . PRO C 1 300 ? -12.899 -5.906  -33.852  1.00 49.83  ? 299 PRO C CD  1 
ATOM   6317  N N   . LEU C 1 301 ? -11.448 -2.834  -32.833  1.00 58.22  ? 300 LEU C N   1 
ATOM   6318  C CA  . LEU C 1 301 ? -10.955 -1.801  -31.917  1.00 57.31  ? 300 LEU C CA  1 
ATOM   6319  C C   . LEU C 1 301 ? -9.533  -1.388  -32.303  1.00 62.75  ? 300 LEU C C   1 
ATOM   6320  O O   . LEU C 1 301 ? -8.549  -1.687  -31.627  1.00 65.65  ? 300 LEU C O   1 
ATOM   6321  C CB  . LEU C 1 301 ? -11.027 -2.298  -30.478  1.00 46.46  ? 300 LEU C CB  1 
ATOM   6322  C CG  . LEU C 1 301 ? -12.405 -2.791  -30.027  1.00 62.19  ? 300 LEU C CG  1 
ATOM   6323  C CD1 . LEU C 1 301 ? -12.406 -3.151  -28.547  1.00 37.72  ? 300 LEU C CD1 1 
ATOM   6324  C CD2 . LEU C 1 301 ? -13.474 -1.754  -30.333  1.00 54.19  ? 300 LEU C CD2 1 
ATOM   6325  N N   . THR C 1 302 ? -9.446  -0.657  -33.409  1.00 60.73  ? 301 THR C N   1 
ATOM   6326  C CA  . THR C 1 302 ? -8.170  -0.251  -33.981  1.00 59.56  ? 301 THR C CA  1 
ATOM   6327  C C   . THR C 1 302 ? -7.844  1.198   -33.634  1.00 59.00  ? 301 THR C C   1 
ATOM   6328  O O   . THR C 1 302 ? -8.736  2.030   -33.451  1.00 62.26  ? 301 THR C O   1 
ATOM   6329  C CB  . THR C 1 302 ? -8.183  -0.416  -35.502  1.00 53.13  ? 301 THR C CB  1 
ATOM   6330  O OG1 . THR C 1 302 ? -9.187  0.438   -36.066  1.00 64.77  ? 301 THR C OG1 1 
ATOM   6331  C CG2 . THR C 1 302 ? -8.475  -1.859  -35.884  1.00 62.76  ? 301 THR C CG2 1 
ATOM   6332  N N   . ILE C 1 303 ? -6.546  1.492   -33.549  1.00 60.15  ? 302 ILE C N   1 
ATOM   6333  C CA  . ILE C 1 303 ? -6.053  2.850   -33.343  1.00 64.08  ? 302 ILE C CA  1 
ATOM   6334  C C   . ILE C 1 303 ? -5.006  3.142   -34.408  1.00 63.58  ? 302 ILE C C   1 
ATOM   6335  O O   . ILE C 1 303 ? -3.976  2.459   -34.472  1.00 64.94  ? 302 ILE C O   1 
ATOM   6336  C CB  . ILE C 1 303 ? -5.457  3.051   -31.939  1.00 53.88  ? 302 ILE C CB  1 
ATOM   6337  C CG1 . ILE C 1 303 ? -6.448  2.613   -30.861  1.00 54.88  ? 302 ILE C CG1 1 
ATOM   6338  C CG2 . ILE C 1 303 ? -5.074  4.510   -31.735  1.00 46.05  ? 302 ILE C CG2 1 
ATOM   6339  C CD1 . ILE C 1 303 ? -5.885  2.687   -29.457  1.00 55.99  ? 302 ILE C CD1 1 
ATOM   6340  N N   . GLY C 1 304 ? -5.263  4.157   -35.237  1.00 59.07  ? 303 GLY C N   1 
ATOM   6341  C CA  . GLY C 1 304 ? -4.334  4.612   -36.246  1.00 58.75  ? 303 GLY C CA  1 
ATOM   6342  C C   . GLY C 1 304 ? -4.990  4.641   -37.607  1.00 60.68  ? 303 GLY C C   1 
ATOM   6343  O O   . GLY C 1 304 ? -6.220  4.658   -37.727  1.00 56.21  ? 303 GLY C O   1 
ATOM   6344  N N   . GLU C 1 305 ? -4.153  4.659   -38.644  1.00 63.78  ? 304 GLU C N   1 
ATOM   6345  C CA  . GLU C 1 305 ? -4.610  4.565   -40.027  1.00 60.61  ? 304 GLU C CA  1 
ATOM   6346  C C   . GLU C 1 305 ? -4.690  3.088   -40.398  1.00 65.62  ? 304 GLU C C   1 
ATOM   6347  O O   . GLU C 1 305 ? -3.662  2.437   -40.612  1.00 70.80  ? 304 GLU C O   1 
ATOM   6348  C CB  . GLU C 1 305 ? -3.672  5.323   -40.962  1.00 58.98  ? 304 GLU C CB  1 
ATOM   6349  C CG  . GLU C 1 305 ? -3.815  6.836   -40.896  1.00 77.18  ? 304 GLU C CG  1 
ATOM   6350  C CD  . GLU C 1 305 ? -2.805  7.557   -41.770  1.00 87.67  ? 304 GLU C CD  1 
ATOM   6351  O OE1 . GLU C 1 305 ? -1.592  7.463   -41.482  1.00 92.99  ? 304 GLU C OE1 1 
ATOM   6352  O OE2 . GLU C 1 305 ? -3.222  8.210   -42.749  1.00 87.53  ? 304 GLU C OE2 1 
ATOM   6353  N N   . CYS C 1 306 ? -5.904  2.565   -40.479  1.00 63.47  ? 305 CYS C N   1 
ATOM   6354  C CA  . CYS C 1 306 ? -6.155  1.137   -40.580  1.00 62.05  ? 305 CYS C CA  1 
ATOM   6355  C C   . CYS C 1 306 ? -7.016  0.827   -41.792  1.00 64.28  ? 305 CYS C C   1 
ATOM   6356  O O   . CYS C 1 306 ? -7.738  1.696   -42.294  1.00 63.38  ? 305 CYS C O   1 
ATOM   6357  C CB  . CYS C 1 306 ? -6.850  0.618   -39.312  1.00 75.24  ? 305 CYS C CB  1 
ATOM   6358  S SG  . CYS C 1 306 ? -5.859  0.736   -37.805  1.00 83.04  ? 305 CYS C SG  1 
ATOM   6359  N N   . PRO C 1 307 ? -6.954  -0.404  -42.296  1.00 58.82  ? 306 PRO C N   1 
ATOM   6360  C CA  . PRO C 1 307 ? -7.876  -0.818  -43.358  1.00 66.37  ? 306 PRO C CA  1 
ATOM   6361  C C   . PRO C 1 307 ? -9.303  -0.891  -42.837  1.00 61.53  ? 306 PRO C C   1 
ATOM   6362  O O   . PRO C 1 307 ? -9.565  -0.888  -41.633  1.00 61.62  ? 306 PRO C O   1 
ATOM   6363  C CB  . PRO C 1 307 ? -7.363  -2.203  -43.766  1.00 62.00  ? 306 PRO C CB  1 
ATOM   6364  C CG  . PRO C 1 307 ? -5.958  -2.270  -43.245  1.00 60.23  ? 306 PRO C CG  1 
ATOM   6365  C CD  . PRO C 1 307 ? -5.953  -1.444  -42.000  1.00 61.13  ? 306 PRO C CD  1 
ATOM   6366  N N   . LYS C 1 308 ? -10.241 -0.952  -43.777  1.00 57.41  ? 307 LYS C N   1 
ATOM   6367  C CA  . LYS C 1 308 ? -11.649 -1.018  -43.413  1.00 59.24  ? 307 LYS C CA  1 
ATOM   6368  C C   . LYS C 1 308 ? -11.999 -2.406  -42.889  1.00 56.48  ? 307 LYS C C   1 
ATOM   6369  O O   . LYS C 1 308 ? -11.709 -3.419  -43.532  1.00 57.38  ? 307 LYS C O   1 
ATOM   6370  C CB  . LYS C 1 308 ? -12.521 -0.655  -44.612  1.00 56.91  ? 307 LYS C CB  1 
ATOM   6371  C CG  . LYS C 1 308 ? -12.424 0.810   -44.999  1.00 55.58  ? 307 LYS C CG  1 
ATOM   6372  C CD  . LYS C 1 308 ? -12.656 1.699   -43.785  1.00 50.63  ? 307 LYS C CD  1 
ATOM   6373  C CE  . LYS C 1 308 ? -12.536 3.173   -44.137  1.00 55.40  ? 307 LYS C CE  1 
ATOM   6374  N NZ  . LYS C 1 308 ? -11.211 3.498   -44.730  1.00 70.53  ? 307 LYS C NZ  1 
ATOM   6375  N N   . TYR C 1 309 ? -12.631 -2.447  -41.719  1.00 56.77  ? 308 TYR C N   1 
ATOM   6376  C CA  . TYR C 1 309 ? -12.966 -3.705  -41.062  1.00 57.19  ? 308 TYR C CA  1 
ATOM   6377  C C   . TYR C 1 309 ? -14.191 -4.322  -41.729  1.00 59.43  ? 308 TYR C C   1 
ATOM   6378  O O   . TYR C 1 309 ? -15.240 -3.678  -41.832  1.00 59.76  ? 308 TYR C O   1 
ATOM   6379  C CB  . TYR C 1 309 ? -13.212 -3.462  -39.574  1.00 57.79  ? 308 TYR C CB  1 
ATOM   6380  C CG  . TYR C 1 309 ? -13.465 -4.709  -38.755  1.00 62.04  ? 308 TYR C CG  1 
ATOM   6381  C CD1 . TYR C 1 309 ? -12.491 -5.690  -38.628  1.00 55.11  ? 308 TYR C CD1 1 
ATOM   6382  C CD2 . TYR C 1 309 ? -14.666 -4.888  -38.082  1.00 53.95  ? 308 TYR C CD2 1 
ATOM   6383  C CE1 . TYR C 1 309 ? -12.716 -6.827  -37.873  1.00 51.49  ? 308 TYR C CE1 1 
ATOM   6384  C CE2 . TYR C 1 309 ? -14.900 -6.020  -37.323  1.00 54.86  ? 308 TYR C CE2 1 
ATOM   6385  C CZ  . TYR C 1 309 ? -13.922 -6.986  -37.222  1.00 59.36  ? 308 TYR C CZ  1 
ATOM   6386  O OH  . TYR C 1 309 ? -14.151 -8.113  -36.467  1.00 57.88  ? 308 TYR C OH  1 
ATOM   6387  N N   . VAL C 1 310 ? -14.056 -5.569  -42.184  1.00 62.47  ? 309 VAL C N   1 
ATOM   6388  C CA  . VAL C 1 310 ? -15.134 -6.294  -42.841  1.00 55.49  ? 309 VAL C CA  1 
ATOM   6389  C C   . VAL C 1 310 ? -15.272 -7.661  -42.186  1.00 57.90  ? 309 VAL C C   1 
ATOM   6390  O O   . VAL C 1 310 ? -14.377 -8.133  -41.481  1.00 66.87  ? 309 VAL C O   1 
ATOM   6391  C CB  . VAL C 1 310 ? -14.901 -6.457  -44.359  1.00 56.10  ? 309 VAL C CB  1 
ATOM   6392  C CG1 . VAL C 1 310 ? -14.726 -5.100  -45.030  1.00 54.52  ? 309 VAL C CG1 1 
ATOM   6393  C CG2 . VAL C 1 310 ? -13.695 -7.349  -44.617  1.00 60.88  ? 309 VAL C CG2 1 
ATOM   6394  N N   . LYS C 1 311 ? -16.419 -8.295  -42.418  1.00 60.62  ? 310 LYS C N   1 
ATOM   6395  C CA  . LYS C 1 311 ? -16.622 -9.694  -42.048  1.00 73.73  ? 310 LYS C CA  1 
ATOM   6396  C C   . LYS C 1 311 ? -16.411 -10.532 -43.304  1.00 76.54  ? 310 LYS C C   1 
ATOM   6397  O O   . LYS C 1 311 ? -17.320 -10.686 -44.123  1.00 82.66  ? 310 LYS C O   1 
ATOM   6398  C CB  . LYS C 1 311 ? -18.002 -9.936  -41.446  1.00 67.28  ? 310 LYS C CB  1 
ATOM   6399  C CG  . LYS C 1 311 ? -18.237 -11.410 -41.133  1.00 79.27  ? 310 LYS C CG  1 
ATOM   6400  C CD  . LYS C 1 311 ? -19.363 -11.631 -40.143  1.00 79.24  ? 310 LYS C CD  1 
ATOM   6401  C CE  . LYS C 1 311 ? -19.264 -13.016 -39.514  1.00 77.00  ? 310 LYS C CE  1 
ATOM   6402  N NZ  . LYS C 1 311 ? -18.087 -13.131 -38.604  1.00 84.75  ? 310 LYS C NZ  1 
ATOM   6403  N N   . SER C 1 312 ? -15.202 -11.060 -43.455  1.00 78.46  ? 311 SER C N   1 
ATOM   6404  C CA  . SER C 1 312 ? -14.872 -11.920 -44.581  1.00 76.58  ? 311 SER C CA  1 
ATOM   6405  C C   . SER C 1 312 ? -13.667 -12.760 -44.197  1.00 82.13  ? 311 SER C C   1 
ATOM   6406  O O   . SER C 1 312 ? -12.884 -12.390 -43.318  1.00 78.59  ? 311 SER C O   1 
ATOM   6407  C CB  . SER C 1 312 ? -14.579 -11.112 -45.851  1.00 71.44  ? 311 SER C CB  1 
ATOM   6408  O OG  . SER C 1 312 ? -15.665 -10.270 -46.193  1.00 84.38  ? 311 SER C OG  1 
ATOM   6409  N N   . ASN C 1 313 ? -13.529 -13.901 -44.868  1.00 90.08  ? 312 ASN C N   1 
ATOM   6410  C CA  . ASN C 1 313 ? -12.356 -14.745 -44.711  1.00 82.53  ? 312 ASN C CA  1 
ATOM   6411  C C   . ASN C 1 313 ? -11.416 -14.677 -45.903  1.00 79.44  ? 312 ASN C C   1 
ATOM   6412  O O   . ASN C 1 313 ? -10.269 -15.124 -45.788  1.00 86.39  ? 312 ASN C O   1 
ATOM   6413  C CB  . ASN C 1 313 ? -12.772 -16.203 -44.467  1.00 85.76  ? 312 ASN C CB  1 
ATOM   6414  C CG  . ASN C 1 313 ? -13.435 -16.400 -43.116  1.00 86.65  ? 312 ASN C CG  1 
ATOM   6415  O OD1 . ASN C 1 313 ? -14.508 -16.996 -43.018  1.00 102.16 ? 312 ASN C OD1 1 
ATOM   6416  N ND2 . ASN C 1 313 ? -12.797 -15.896 -42.066  1.00 85.68  ? 312 ASN C ND2 1 
ATOM   6417  N N   . LYS C 1 314 ? -11.863 -14.127 -47.031  1.00 68.39  ? 313 LYS C N   1 
ATOM   6418  C CA  . LYS C 1 314 ? -11.015 -13.943 -48.200  1.00 78.29  ? 313 LYS C CA  1 
ATOM   6419  C C   . LYS C 1 314 ? -11.726 -13.037 -49.192  1.00 79.44  ? 313 LYS C C   1 
ATOM   6420  O O   . LYS C 1 314 ? -12.945 -13.129 -49.363  1.00 82.51  ? 313 LYS C O   1 
ATOM   6421  C CB  . LYS C 1 314 ? -10.666 -15.286 -48.857  1.00 80.09  ? 313 LYS C CB  1 
ATOM   6422  C CG  . LYS C 1 314 ? -11.856 -16.070 -49.390  1.00 81.88  ? 313 LYS C CG  1 
ATOM   6423  C CD  . LYS C 1 314 ? -11.513 -17.546 -49.486  1.00 89.00  ? 313 LYS C CD  1 
ATOM   6424  C CE  . LYS C 1 314 ? -12.320 -18.249 -50.560  1.00 84.29  ? 313 LYS C CE  1 
ATOM   6425  N NZ  . LYS C 1 314 ? -11.769 -19.606 -50.831  1.00 97.91  ? 313 LYS C NZ  1 
ATOM   6426  N N   . LEU C 1 315 ? -10.957 -12.150 -49.828  1.00 62.47  ? 314 LEU C N   1 
ATOM   6427  C CA  . LEU C 1 315 ? -11.426 -11.319 -50.939  1.00 69.24  ? 314 LEU C CA  1 
ATOM   6428  C C   . LEU C 1 315 ? -10.424 -11.531 -52.070  1.00 81.91  ? 314 LEU C C   1 
ATOM   6429  O O   . LEU C 1 315 ? -9.488  -10.747 -52.246  1.00 76.63  ? 314 LEU C O   1 
ATOM   6430  C CB  . LEU C 1 315 ? -11.538 -9.850  -50.531  1.00 77.24  ? 314 LEU C CB  1 
ATOM   6431  C CG  . LEU C 1 315 ? -12.525 -9.519  -49.410  1.00 72.71  ? 314 LEU C CG  1 
ATOM   6432  C CD1 . LEU C 1 315 ? -12.130 -8.223  -48.724  1.00 77.60  ? 314 LEU C CD1 1 
ATOM   6433  C CD2 . LEU C 1 315 ? -13.943 -9.425  -49.952  1.00 61.07  ? 314 LEU C CD2 1 
ATOM   6434  N N   . VAL C 1 316 ? -10.632 -12.592 -52.843  1.00 78.96  ? 315 VAL C N   1 
ATOM   6435  C CA  . VAL C 1 316 ? -9.647  -13.055 -53.813  1.00 77.41  ? 315 VAL C CA  1 
ATOM   6436  C C   . VAL C 1 316 ? -9.970  -12.434 -55.167  1.00 74.94  ? 315 VAL C C   1 
ATOM   6437  O O   . VAL C 1 316 ? -10.995 -12.748 -55.778  1.00 76.56  ? 315 VAL C O   1 
ATOM   6438  C CB  . VAL C 1 316 ? -9.622  -14.585 -53.897  1.00 80.71  ? 315 VAL C CB  1 
ATOM   6439  C CG1 . VAL C 1 316 ? -8.331  -15.059 -54.544  1.00 81.73  ? 315 VAL C CG1 1 
ATOM   6440  C CG2 . VAL C 1 316 ? -9.793  -15.196 -52.512  1.00 81.75  ? 315 VAL C CG2 1 
ATOM   6441  N N   . LEU C 1 317 ? -9.092  -11.552 -55.637  1.00 71.23  ? 316 LEU C N   1 
ATOM   6442  C CA  . LEU C 1 317 ? -9.211  -10.967 -56.964  1.00 80.15  ? 316 LEU C CA  1 
ATOM   6443  C C   . LEU C 1 317 ? -8.470  -11.833 -57.972  1.00 91.39  ? 316 LEU C C   1 
ATOM   6444  O O   . LEU C 1 317 ? -7.288  -12.139 -57.787  1.00 93.11  ? 316 LEU C O   1 
ATOM   6445  C CB  . LEU C 1 317 ? -8.649  -9.546  -56.986  1.00 73.37  ? 316 LEU C CB  1 
ATOM   6446  C CG  . LEU C 1 317 ? -9.578  -8.407  -56.570  1.00 81.73  ? 316 LEU C CG  1 
ATOM   6447  C CD1 . LEU C 1 317 ? -8.789  -7.115  -56.477  1.00 69.09  ? 316 LEU C CD1 1 
ATOM   6448  C CD2 . LEU C 1 317 ? -10.725 -8.268  -57.558  1.00 71.51  ? 316 LEU C CD2 1 
ATOM   6449  N N   . ALA C 1 318 ? -9.165  -12.225 -59.035  1.00 91.11  ? 317 ALA C N   1 
ATOM   6450  C CA  . ALA C 1 318 ? -8.548  -13.006 -60.097  1.00 93.66  ? 317 ALA C CA  1 
ATOM   6451  C C   . ALA C 1 318 ? -7.780  -12.072 -61.023  1.00 86.38  ? 317 ALA C C   1 
ATOM   6452  O O   . ALA C 1 318 ? -8.357  -11.137 -61.589  1.00 71.75  ? 317 ALA C O   1 
ATOM   6453  C CB  . ALA C 1 318 ? -9.605  -13.792 -60.870  1.00 86.62  ? 317 ALA C CB  1 
ATOM   6454  N N   . THR C 1 319 ? -6.477  -12.315 -61.167  1.00 88.44  ? 318 THR C N   1 
ATOM   6455  C CA  . THR C 1 319 ? -5.644  -11.536 -62.071  1.00 94.91  ? 318 THR C CA  1 
ATOM   6456  C C   . THR C 1 319 ? -5.175  -12.315 -63.289  1.00 112.59 ? 318 THR C C   1 
ATOM   6457  O O   . THR C 1 319 ? -4.821  -11.695 -64.297  1.00 99.89  ? 318 THR C O   1 
ATOM   6458  C CB  . THR C 1 319 ? -4.418  -10.982 -61.328  1.00 101.70 ? 318 THR C CB  1 
ATOM   6459  O OG1 . THR C 1 319 ? -3.448  -10.518 -62.277  1.00 112.11 ? 318 THR C OG1 1 
ATOM   6460  C CG2 . THR C 1 319 ? -3.797  -12.050 -60.445  1.00 97.96  ? 318 THR C CG2 1 
ATOM   6461  N N   . GLY C 1 320 ? -5.171  -13.648 -63.227  1.00 110.64 ? 319 GLY C N   1 
ATOM   6462  C CA  . GLY C 1 320 ? -4.802  -14.474 -64.354  1.00 115.79 ? 319 GLY C CA  1 
ATOM   6463  C C   . GLY C 1 320 ? -6.014  -14.997 -65.115  1.00 118.91 ? 319 GLY C C   1 
ATOM   6464  O O   . GLY C 1 320 ? -7.163  -14.666 -64.834  1.00 112.75 ? 319 GLY C O   1 
ATOM   6465  N N   . LEU C 1 321 ? -5.727  -15.842 -66.102  1.00 118.23 ? 320 LEU C N   1 
ATOM   6466  C CA  . LEU C 1 321 ? -6.771  -16.395 -66.948  1.00 106.98 ? 320 LEU C CA  1 
ATOM   6467  C C   . LEU C 1 321 ? -7.418  -17.611 -66.292  1.00 105.68 ? 320 LEU C C   1 
ATOM   6468  O O   . LEU C 1 321 ? -6.968  -18.117 -65.260  1.00 112.96 ? 320 LEU C O   1 
ATOM   6469  C CB  . LEU C 1 321 ? -6.217  -16.775 -68.320  1.00 109.41 ? 320 LEU C CB  1 
ATOM   6470  C CG  . LEU C 1 321 ? -5.745  -15.632 -69.218  1.00 111.44 ? 320 LEU C CG  1 
ATOM   6471  C CD1 . LEU C 1 321 ? -4.275  -15.348 -68.990  1.00 114.60 ? 320 LEU C CD1 1 
ATOM   6472  C CD2 . LEU C 1 321 ? -6.017  -15.948 -70.679  1.00 117.76 ? 320 LEU C CD2 1 
ATOM   6473  N N   . ARG C 1 322 ? -8.498  -18.078 -66.915  1.00 109.25 ? 321 ARG C N   1 
ATOM   6474  C CA  . ARG C 1 322 ? -9.196  -19.268 -66.449  1.00 105.38 ? 321 ARG C CA  1 
ATOM   6475  C C   . ARG C 1 322 ? -8.322  -20.494 -66.692  1.00 105.13 ? 321 ARG C C   1 
ATOM   6476  O O   . ARG C 1 322 ? -7.943  -20.778 -67.833  1.00 106.03 ? 321 ARG C O   1 
ATOM   6477  C CB  . ARG C 1 322 ? -10.534 -19.397 -67.172  1.00 102.87 ? 321 ARG C CB  1 
ATOM   6478  C CG  . ARG C 1 322 ? -11.557 -20.280 -66.478  1.00 104.13 ? 321 ARG C CG  1 
ATOM   6479  C CD  . ARG C 1 322 ? -12.844 -20.351 -67.290  1.00 101.75 ? 321 ARG C CD  1 
ATOM   6480  N NE  . ARG C 1 322 ? -13.516 -19.060 -67.389  1.00 92.73  ? 321 ARG C NE  1 
ATOM   6481  C CZ  . ARG C 1 322 ? -14.658 -18.761 -66.785  1.00 97.65  ? 321 ARG C CZ  1 
ATOM   6482  N NH1 . ARG C 1 322 ? -15.297 -19.646 -66.037  1.00 70.55  ? 321 ARG C NH1 1 
ATOM   6483  N NH2 . ARG C 1 322 ? -15.178 -17.547 -66.944  1.00 93.35  ? 321 ARG C NH2 1 
ATOM   6484  N N   . ASN C 1 323 ? -7.999  -21.217 -65.623  1.00 112.18 ? 322 ASN C N   1 
ATOM   6485  C CA  . ASN C 1 323 ? -7.066  -22.332 -65.701  1.00 123.78 ? 322 ASN C CA  1 
ATOM   6486  C C   . ASN C 1 323 ? -7.791  -23.633 -66.016  1.00 125.51 ? 322 ASN C C   1 
ATOM   6487  O O   . ASN C 1 323 ? -8.853  -23.922 -65.457  1.00 114.49 ? 322 ASN C O   1 
ATOM   6488  C CB  . ASN C 1 323 ? -6.289  -22.481 -64.391  1.00 117.91 ? 322 ASN C CB  1 
ATOM   6489  C CG  . ASN C 1 323 ? -5.291  -23.623 -64.433  1.00 122.21 ? 322 ASN C CG  1 
ATOM   6490  O OD1 . ASN C 1 323 ? -4.760  -23.961 -65.492  1.00 128.53 ? 322 ASN C OD1 1 
ATOM   6491  N ND2 . ASN C 1 323 ? -5.035  -24.229 -63.279  1.00 116.24 ? 322 ASN C ND2 1 
ATOM   6492  N N   . SER C 1 324 ? -7.203  -24.418 -66.916  1.00 136.63 ? 323 SER C N   1 
ATOM   6493  C CA  . SER C 1 324 ? -7.703  -25.742 -67.262  1.00 136.74 ? 323 SER C CA  1 
ATOM   6494  C C   . SER C 1 324 ? -6.593  -26.759 -67.038  1.00 141.83 ? 323 SER C C   1 
ATOM   6495  O O   . SER C 1 324 ? -5.508  -26.623 -67.631  1.00 137.63 ? 323 SER C O   1 
ATOM   6496  C CB  . SER C 1 324 ? -8.187  -25.785 -68.713  1.00 133.15 ? 323 SER C CB  1 
ATOM   6497  O OG  . SER C 1 324 ? -8.746  -27.050 -69.027  1.00 132.86 ? 323 SER C OG  1 
ATOM   6498  N N   . PRO C 1 325 ? -6.801  -27.786 -66.200  1.00 145.07 ? 324 PRO C N   1 
ATOM   6499  C CA  . PRO C 1 325 ? -5.774  -28.795 -65.915  1.00 140.13 ? 324 PRO C CA  1 
ATOM   6500  C C   . PRO C 1 325 ? -5.475  -29.689 -67.115  1.00 137.85 ? 324 PRO C C   1 
ATOM   6501  O O   . PRO C 1 325 ? -5.760  -30.885 -67.057  1.00 135.81 ? 324 PRO C O   1 
ATOM   6502  C CB  . PRO C 1 325 ? -6.390  -29.606 -64.771  1.00 132.28 ? 324 PRO C CB  1 
ATOM   6503  C CG  . PRO C 1 325 ? -7.860  -29.445 -64.952  1.00 129.32 ? 324 PRO C CG  1 
ATOM   6504  C CD  . PRO C 1 325 ? -8.052  -28.048 -65.466  1.00 134.33 ? 324 PRO C CD  1 
ATOM   6505  N N   . GLY D 2 1   ? -17.248 -17.458 -71.465  1.00 126.81 ? 1   GLY D N   1 
ATOM   6506  C CA  . GLY D 2 1   ? -17.515 -16.079 -71.098  1.00 137.76 ? 1   GLY D CA  1 
ATOM   6507  C C   . GLY D 2 1   ? -18.538 -15.408 -71.993  1.00 145.17 ? 1   GLY D C   1 
ATOM   6508  O O   . GLY D 2 1   ? -19.518 -16.029 -72.406  1.00 141.82 ? 1   GLY D O   1 
ATOM   6509  N N   . LEU D 2 2   ? -18.311 -14.129 -72.293  1.00 142.56 ? 2   LEU D N   1 
ATOM   6510  C CA  . LEU D 2 2   ? -19.200 -13.376 -73.173  1.00 145.09 ? 2   LEU D CA  1 
ATOM   6511  C C   . LEU D 2 2   ? -18.784 -13.509 -74.636  1.00 144.97 ? 2   LEU D C   1 
ATOM   6512  O O   . LEU D 2 2   ? -19.554 -13.996 -75.469  1.00 136.83 ? 2   LEU D O   1 
ATOM   6513  C CB  . LEU D 2 2   ? -19.224 -11.897 -72.768  1.00 134.60 ? 2   LEU D CB  1 
ATOM   6514  C CG  . LEU D 2 2   ? -19.883 -11.500 -71.447  1.00 134.14 ? 2   LEU D CG  1 
ATOM   6515  C CD1 . LEU D 2 2   ? -19.846 -9.987  -71.271  1.00 125.87 ? 2   LEU D CD1 1 
ATOM   6516  C CD2 . LEU D 2 2   ? -21.309 -12.009 -71.387  1.00 115.60 ? 2   LEU D CD2 1 
ATOM   6517  N N   . PHE D 2 3   ? -17.558 -13.088 -74.954  1.00 152.35 ? 3   PHE D N   1 
ATOM   6518  C CA  . PHE D 2 3   ? -17.114 -13.031 -76.341  1.00 152.27 ? 3   PHE D CA  1 
ATOM   6519  C C   . PHE D 2 3   ? -16.855 -14.413 -76.928  1.00 152.13 ? 3   PHE D C   1 
ATOM   6520  O O   . PHE D 2 3   ? -16.856 -14.561 -78.155  1.00 146.70 ? 3   PHE D O   1 
ATOM   6521  C CB  . PHE D 2 3   ? -15.863 -12.155 -76.443  1.00 145.22 ? 3   PHE D CB  1 
ATOM   6522  C CG  . PHE D 2 3   ? -16.067 -10.749 -75.938  1.00 140.02 ? 3   PHE D CG  1 
ATOM   6523  C CD1 . PHE D 2 3   ? -15.965 -10.460 -74.585  1.00 136.11 ? 3   PHE D CD1 1 
ATOM   6524  C CD2 . PHE D 2 3   ? -16.364 -9.719  -76.816  1.00 138.31 ? 3   PHE D CD2 1 
ATOM   6525  C CE1 . PHE D 2 3   ? -16.156 -9.172  -74.118  1.00 135.56 ? 3   PHE D CE1 1 
ATOM   6526  C CE2 . PHE D 2 3   ? -16.553 -8.428  -76.354  1.00 139.43 ? 3   PHE D CE2 1 
ATOM   6527  C CZ  . PHE D 2 3   ? -16.449 -8.155  -75.004  1.00 138.28 ? 3   PHE D CZ  1 
ATOM   6528  N N   . GLY D 2 4   ? -16.631 -15.422 -76.088  1.00 157.82 ? 4   GLY D N   1 
ATOM   6529  C CA  . GLY D 2 4   ? -16.535 -16.794 -76.549  1.00 160.51 ? 4   GLY D CA  1 
ATOM   6530  C C   . GLY D 2 4   ? -15.173 -17.211 -77.065  1.00 166.86 ? 4   GLY D C   1 
ATOM   6531  O O   . GLY D 2 4   ? -15.057 -17.691 -78.197  1.00 165.51 ? 4   GLY D O   1 
ATOM   6532  N N   . ALA D 2 5   ? -14.131 -17.037 -76.252  1.00 164.29 ? 5   ALA D N   1 
ATOM   6533  C CA  . ALA D 2 5   ? -12.792 -17.483 -76.616  1.00 158.64 ? 5   ALA D CA  1 
ATOM   6534  C C   . ALA D 2 5   ? -12.215 -18.486 -75.630  1.00 156.39 ? 5   ALA D C   1 
ATOM   6535  O O   . ALA D 2 5   ? -11.707 -19.533 -76.049  1.00 156.47 ? 5   ALA D O   1 
ATOM   6536  C CB  . ALA D 2 5   ? -11.848 -16.280 -76.751  1.00 148.65 ? 5   ALA D CB  1 
ATOM   6537  N N   . ILE D 2 6   ? -12.267 -18.196 -74.327  1.00 152.81 ? 6   ILE D N   1 
ATOM   6538  C CA  . ILE D 2 6   ? -11.733 -19.130 -73.340  1.00 158.46 ? 6   ILE D CA  1 
ATOM   6539  C C   . ILE D 2 6   ? -12.542 -20.422 -73.334  1.00 164.28 ? 6   ILE D C   1 
ATOM   6540  O O   . ILE D 2 6   ? -11.980 -21.523 -73.298  1.00 158.72 ? 6   ILE D O   1 
ATOM   6541  C CB  . ILE D 2 6   ? -11.695 -18.481 -71.944  1.00 153.64 ? 6   ILE D CB  1 
ATOM   6542  C CG1 . ILE D 2 6   ? -10.937 -17.154 -71.986  1.00 137.64 ? 6   ILE D CG1 1 
ATOM   6543  C CG2 . ILE D 2 6   ? -11.049 -19.421 -70.938  1.00 143.63 ? 6   ILE D CG2 1 
ATOM   6544  C CD1 . ILE D 2 6   ? -9.495  -17.282 -72.410  1.00 129.95 ? 6   ILE D CD1 1 
ATOM   6545  N N   . ALA D 2 7   ? -13.871 -20.310 -73.374  1.00 171.06 ? 7   ALA D N   1 
ATOM   6546  C CA  . ALA D 2 7   ? -14.757 -21.468 -73.411  1.00 169.03 ? 7   ALA D CA  1 
ATOM   6547  C C   . ALA D 2 7   ? -15.561 -21.530 -74.705  1.00 172.16 ? 7   ALA D C   1 
ATOM   6548  O O   . ALA D 2 7   ? -16.621 -22.162 -74.744  1.00 170.21 ? 7   ALA D O   1 
ATOM   6549  C CB  . ALA D 2 7   ? -15.696 -21.465 -72.202  1.00 159.31 ? 7   ALA D CB  1 
ATOM   6550  N N   . GLY D 2 8   ? -15.076 -20.888 -75.766  1.00 169.73 ? 8   GLY D N   1 
ATOM   6551  C CA  . GLY D 2 8   ? -15.778 -20.880 -77.034  1.00 165.84 ? 8   GLY D CA  1 
ATOM   6552  C C   . GLY D 2 8   ? -15.261 -21.919 -78.006  1.00 166.57 ? 8   GLY D C   1 
ATOM   6553  O O   . GLY D 2 8   ? -15.487 -23.119 -77.820  1.00 164.12 ? 8   GLY D O   1 
ATOM   6554  N N   . PHE D 2 9   ? -14.565 -21.472 -79.052  1.00 163.01 ? 9   PHE D N   1 
ATOM   6555  C CA  . PHE D 2 9   ? -14.021 -22.388 -80.045  1.00 161.26 ? 9   PHE D CA  1 
ATOM   6556  C C   . PHE D 2 9   ? -12.567 -22.762 -79.793  1.00 157.10 ? 9   PHE D C   1 
ATOM   6557  O O   . PHE D 2 9   ? -12.132 -23.823 -80.252  1.00 157.79 ? 9   PHE D O   1 
ATOM   6558  C CB  . PHE D 2 9   ? -14.173 -21.811 -81.465  1.00 156.13 ? 9   PHE D CB  1 
ATOM   6559  C CG  . PHE D 2 9   ? -13.647 -20.401 -81.643  1.00 153.34 ? 9   PHE D CG  1 
ATOM   6560  C CD1 . PHE D 2 9   ? -14.343 -19.308 -81.144  1.00 157.73 ? 9   PHE D CD1 1 
ATOM   6561  C CD2 . PHE D 2 9   ? -12.488 -20.167 -82.369  1.00 155.54 ? 9   PHE D CD2 1 
ATOM   6562  C CE1 . PHE D 2 9   ? -13.869 -18.018 -81.328  1.00 158.19 ? 9   PHE D CE1 1 
ATOM   6563  C CE2 . PHE D 2 9   ? -12.014 -18.877 -82.559  1.00 157.67 ? 9   PHE D CE2 1 
ATOM   6564  C CZ  . PHE D 2 9   ? -12.705 -17.804 -82.037  1.00 156.83 ? 9   PHE D CZ  1 
ATOM   6565  N N   . ILE D 2 10  ? -11.811 -21.929 -79.077  1.00 151.84 ? 10  ILE D N   1 
ATOM   6566  C CA  . ILE D 2 10  ? -10.448 -22.294 -78.702  1.00 142.40 ? 10  ILE D CA  1 
ATOM   6567  C C   . ILE D 2 10  ? -10.471 -23.434 -77.689  1.00 142.32 ? 10  ILE D C   1 
ATOM   6568  O O   . ILE D 2 10  ? -9.780  -24.446 -77.852  1.00 133.76 ? 10  ILE D O   1 
ATOM   6569  C CB  . ILE D 2 10  ? -9.695  -21.063 -78.158  1.00 129.98 ? 10  ILE D CB  1 
ATOM   6570  C CG1 . ILE D 2 10  ? -9.585  -19.967 -79.225  1.00 126.17 ? 10  ILE D CG1 1 
ATOM   6571  C CG2 . ILE D 2 10  ? -8.306  -21.446 -77.696  1.00 131.72 ? 10  ILE D CG2 1 
ATOM   6572  C CD1 . ILE D 2 10  ? -10.765 -18.968 -79.254  1.00 125.58 ? 10  ILE D CD1 1 
ATOM   6573  N N   . GLU D 2 11  ? -11.275 -23.274 -76.634  1.00 149.41 ? 11  GLU D N   1 
ATOM   6574  C CA  . GLU D 2 11  ? -11.566 -24.285 -75.605  1.00 146.15 ? 11  GLU D CA  1 
ATOM   6575  C C   . GLU D 2 11  ? -10.347 -25.142 -75.254  1.00 136.53 ? 11  GLU D C   1 
ATOM   6576  O O   . GLU D 2 11  ? -10.420 -26.364 -75.098  1.00 130.05 ? 11  GLU D O   1 
ATOM   6577  C CB  . GLU D 2 11  ? -12.776 -25.146 -76.004  1.00 144.28 ? 11  GLU D CB  1 
ATOM   6578  C CG  . GLU D 2 11  ? -12.590 -26.231 -77.069  1.00 146.36 ? 11  GLU D CG  1 
ATOM   6579  C CD  . GLU D 2 11  ? -13.430 -27.467 -76.756  1.00 141.65 ? 11  GLU D CD  1 
ATOM   6580  O OE1 . GLU D 2 11  ? -13.990 -28.081 -77.688  1.00 130.34 ? 11  GLU D OE1 1 
ATOM   6581  O OE2 . GLU D 2 11  ? -13.541 -27.814 -75.560  1.00 133.76 ? 11  GLU D OE2 1 
ATOM   6582  N N   . GLY D 2 12  ? -9.214  -24.476 -75.074  1.00 136.56 ? 12  GLY D N   1 
ATOM   6583  C CA  . GLY D 2 12  ? -8.012  -25.202 -74.724  1.00 131.75 ? 12  GLY D CA  1 
ATOM   6584  C C   . GLY D 2 12  ? -7.090  -24.460 -73.782  1.00 127.93 ? 12  GLY D C   1 
ATOM   6585  O O   . GLY D 2 12  ? -6.650  -23.344 -74.076  1.00 132.64 ? 12  GLY D O   1 
ATOM   6586  N N   . GLY D 2 13  ? -6.785  -25.077 -72.645  1.00 119.42 ? 13  GLY D N   1 
ATOM   6587  C CA  . GLY D 2 13  ? -5.787  -24.538 -71.747  1.00 125.39 ? 13  GLY D CA  1 
ATOM   6588  C C   . GLY D 2 13  ? -4.412  -25.069 -72.089  1.00 128.69 ? 13  GLY D C   1 
ATOM   6589  O O   . GLY D 2 13  ? -4.100  -26.227 -71.795  1.00 119.62 ? 13  GLY D O   1 
ATOM   6590  N N   . TRP D 2 14  ? -3.580  -24.240 -72.717  1.00 136.28 ? 14  TRP D N   1 
ATOM   6591  C CA  . TRP D 2 14  ? -2.270  -24.686 -73.174  1.00 129.39 ? 14  TRP D CA  1 
ATOM   6592  C C   . TRP D 2 14  ? -1.318  -24.852 -71.998  1.00 128.88 ? 14  TRP D C   1 
ATOM   6593  O O   . TRP D 2 14  ? -0.646  -23.899 -71.589  1.00 131.78 ? 14  TRP D O   1 
ATOM   6594  C CB  . TRP D 2 14  ? -1.700  -23.708 -74.203  1.00 132.66 ? 14  TRP D CB  1 
ATOM   6595  C CG  . TRP D 2 14  ? -2.346  -23.816 -75.551  1.00 126.36 ? 14  TRP D CG  1 
ATOM   6596  C CD1 . TRP D 2 14  ? -3.279  -24.733 -75.941  1.00 117.29 ? 14  TRP D CD1 1 
ATOM   6597  C CD2 . TRP D 2 14  ? -2.107  -22.978 -76.689  1.00 133.14 ? 14  TRP D CD2 1 
ATOM   6598  N NE1 . TRP D 2 14  ? -3.636  -24.517 -77.250  1.00 122.67 ? 14  TRP D NE1 1 
ATOM   6599  C CE2 . TRP D 2 14  ? -2.931  -23.446 -77.732  1.00 128.28 ? 14  TRP D CE2 1 
ATOM   6600  C CE3 . TRP D 2 14  ? -1.277  -21.878 -76.927  1.00 136.07 ? 14  TRP D CE3 1 
ATOM   6601  C CZ2 . TRP D 2 14  ? -2.949  -22.852 -78.993  1.00 134.68 ? 14  TRP D CZ2 1 
ATOM   6602  C CZ3 . TRP D 2 14  ? -1.297  -21.291 -78.179  1.00 137.90 ? 14  TRP D CZ3 1 
ATOM   6603  C CH2 . TRP D 2 14  ? -2.128  -21.778 -79.195  1.00 139.15 ? 14  TRP D CH2 1 
ATOM   6604  N N   . GLN D 2 15  ? -1.258  -26.070 -71.453  1.00 126.46 ? 15  GLN D N   1 
ATOM   6605  C CA  . GLN D 2 15  ? -0.314  -26.362 -70.378  1.00 122.23 ? 15  GLN D CA  1 
ATOM   6606  C C   . GLN D 2 15  ? 1.123   -26.217 -70.858  1.00 132.00 ? 15  GLN D C   1 
ATOM   6607  O O   . GLN D 2 15  ? 1.976   -25.682 -70.139  1.00 134.86 ? 15  GLN D O   1 
ATOM   6608  C CB  . GLN D 2 15  ? -0.559  -27.769 -69.836  1.00 110.68 ? 15  GLN D CB  1 
ATOM   6609  C CG  . GLN D 2 15  ? -1.828  -27.913 -69.012  1.00 120.03 ? 15  GLN D CG  1 
ATOM   6610  C CD  . GLN D 2 15  ? -1.673  -27.364 -67.606  1.00 133.24 ? 15  GLN D CD  1 
ATOM   6611  O OE1 . GLN D 2 15  ? -0.577  -27.364 -67.045  1.00 127.99 ? 15  GLN D OE1 1 
ATOM   6612  N NE2 . GLN D 2 15  ? -2.773  -26.890 -67.031  1.00 134.05 ? 15  GLN D NE2 1 
ATOM   6613  N N   . GLY D 2 16  ? 1.409   -26.689 -72.074  1.00 135.30 ? 16  GLY D N   1 
ATOM   6614  C CA  . GLY D 2 16  ? 2.750   -26.601 -72.620  1.00 131.27 ? 16  GLY D CA  1 
ATOM   6615  C C   . GLY D 2 16  ? 3.220   -25.188 -72.881  1.00 134.81 ? 16  GLY D C   1 
ATOM   6616  O O   . GLY D 2 16  ? 4.429   -24.960 -72.993  1.00 138.81 ? 16  GLY D O   1 
ATOM   6617  N N   . MET D 2 17  ? 2.298   -24.235 -72.984  1.00 131.24 ? 17  MET D N   1 
ATOM   6618  C CA  . MET D 2 17  ? 2.659   -22.831 -73.151  1.00 136.58 ? 17  MET D CA  1 
ATOM   6619  C C   . MET D 2 17  ? 2.897   -22.230 -71.773  1.00 142.05 ? 17  MET D C   1 
ATOM   6620  O O   . MET D 2 17  ? 1.952   -21.855 -71.072  1.00 138.73 ? 17  MET D O   1 
ATOM   6621  C CB  . MET D 2 17  ? 1.578   -22.067 -73.908  1.00 132.08 ? 17  MET D CB  1 
ATOM   6622  C CG  . MET D 2 17  ? 1.780   -20.558 -73.859  1.00 134.85 ? 17  MET D CG  1 
ATOM   6623  S SD  . MET D 2 17  ? 1.274   -19.676 -75.341  1.00 153.52 ? 17  MET D SD  1 
ATOM   6624  C CE  . MET D 2 17  ? 2.293   -18.213 -75.185  1.00 137.02 ? 17  MET D CE  1 
ATOM   6625  N N   . VAL D 2 18  ? 4.162   -22.161 -71.365  1.00 145.92 ? 18  VAL D N   1 
ATOM   6626  C CA  . VAL D 2 18  ? 4.512   -21.310 -70.237  1.00 145.00 ? 18  VAL D CA  1 
ATOM   6627  C C   . VAL D 2 18  ? 5.551   -20.299 -70.706  1.00 145.60 ? 18  VAL D C   1 
ATOM   6628  O O   . VAL D 2 18  ? 6.756   -20.476 -70.498  1.00 145.15 ? 18  VAL D O   1 
ATOM   6629  C CB  . VAL D 2 18  ? 5.023   -22.149 -69.049  1.00 143.34 ? 18  VAL D CB  1 
ATOM   6630  C CG1 . VAL D 2 18  ? 3.851   -22.725 -68.272  1.00 139.36 ? 18  VAL D CG1 1 
ATOM   6631  C CG2 . VAL D 2 18  ? 5.922   -23.278 -69.541  1.00 131.91 ? 18  VAL D CG2 1 
ATOM   6632  N N   . ASP D 2 19  ? 5.080   -19.229 -71.336  1.00 145.58 ? 19  ASP D N   1 
ATOM   6633  C CA  . ASP D 2 19  ? 5.921   -18.075 -71.622  1.00 150.14 ? 19  ASP D CA  1 
ATOM   6634  C C   . ASP D 2 19  ? 5.150   -16.765 -71.572  1.00 146.84 ? 19  ASP D C   1 
ATOM   6635  O O   . ASP D 2 19  ? 5.740   -15.716 -71.843  1.00 147.44 ? 19  ASP D O   1 
ATOM   6636  C CB  . ASP D 2 19  ? 6.597   -18.238 -72.993  1.00 161.13 ? 19  ASP D CB  1 
ATOM   6637  C CG  . ASP D 2 19  ? 7.927   -17.514 -73.077  1.00 172.84 ? 19  ASP D CG  1 
ATOM   6638  O OD1 . ASP D 2 19  ? 8.362   -16.945 -72.053  1.00 175.54 ? 19  ASP D OD1 1 
ATOM   6639  O OD2 . ASP D 2 19  ? 8.539   -17.515 -74.166  1.00 177.21 ? 19  ASP D OD2 1 
ATOM   6640  N N   . GLY D 2 20  ? 3.868   -16.785 -71.239  1.00 142.76 ? 20  GLY D N   1 
ATOM   6641  C CA  . GLY D 2 20  ? 3.031   -15.610 -71.351  1.00 139.75 ? 20  GLY D CA  1 
ATOM   6642  C C   . GLY D 2 20  ? 1.570   -16.016 -71.334  1.00 129.29 ? 20  GLY D C   1 
ATOM   6643  O O   . GLY D 2 20  ? 1.230   -17.165 -71.058  1.00 122.04 ? 20  GLY D O   1 
ATOM   6644  N N   . TRP D 2 21  ? 0.715   -15.044 -71.652  1.00 123.44 ? 21  TRP D N   1 
ATOM   6645  C CA  . TRP D 2 21  ? -0.730  -15.230 -71.563  1.00 128.49 ? 21  TRP D CA  1 
ATOM   6646  C C   . TRP D 2 21  ? -1.370  -15.533 -72.916  1.00 134.23 ? 21  TRP D C   1 
ATOM   6647  O O   . TRP D 2 21  ? -2.022  -16.568 -73.076  1.00 124.93 ? 21  TRP D O   1 
ATOM   6648  C CB  . TRP D 2 21  ? -1.372  -13.990 -70.927  1.00 128.53 ? 21  TRP D CB  1 
ATOM   6649  C CG  . TRP D 2 21  ? -1.258  -13.976 -69.434  1.00 127.12 ? 21  TRP D CG  1 
ATOM   6650  C CD1 . TRP D 2 21  ? -0.680  -14.931 -68.649  1.00 128.78 ? 21  TRP D CD1 1 
ATOM   6651  C CD2 . TRP D 2 21  ? -1.748  -12.967 -68.543  1.00 122.97 ? 21  TRP D CD2 1 
ATOM   6652  N NE1 . TRP D 2 21  ? -0.774  -14.576 -67.325  1.00 126.75 ? 21  TRP D NE1 1 
ATOM   6653  C CE2 . TRP D 2 21  ? -1.426  -13.375 -67.233  1.00 124.11 ? 21  TRP D CE2 1 
ATOM   6654  C CE3 . TRP D 2 21  ? -2.426  -11.757 -68.726  1.00 117.57 ? 21  TRP D CE3 1 
ATOM   6655  C CZ2 . TRP D 2 21  ? -1.757  -12.616 -66.113  1.00 114.59 ? 21  TRP D CZ2 1 
ATOM   6656  C CZ3 . TRP D 2 21  ? -2.753  -11.006 -67.612  1.00 113.09 ? 21  TRP D CZ3 1 
ATOM   6657  C CH2 . TRP D 2 21  ? -2.418  -11.438 -66.323  1.00 115.10 ? 21  TRP D CH2 1 
ATOM   6658  N N   . TYR D 2 22  ? -1.194  -14.651 -73.893  1.00 138.54 ? 22  TYR D N   1 
ATOM   6659  C CA  . TYR D 2 22  ? -1.802  -14.796 -75.209  1.00 134.81 ? 22  TYR D CA  1 
ATOM   6660  C C   . TYR D 2 22  ? -0.724  -15.150 -76.223  1.00 145.38 ? 22  TYR D C   1 
ATOM   6661  O O   . TYR D 2 22  ? 0.297   -14.459 -76.316  1.00 144.33 ? 22  TYR D O   1 
ATOM   6662  C CB  . TYR D 2 22  ? -2.518  -13.509 -75.628  1.00 130.17 ? 22  TYR D CB  1 
ATOM   6663  C CG  . TYR D 2 22  ? -3.402  -12.918 -74.552  1.00 132.27 ? 22  TYR D CG  1 
ATOM   6664  C CD1 . TYR D 2 22  ? -4.206  -13.729 -73.760  1.00 130.01 ? 22  TYR D CD1 1 
ATOM   6665  C CD2 . TYR D 2 22  ? -3.423  -11.549 -74.322  1.00 128.60 ? 22  TYR D CD2 1 
ATOM   6666  C CE1 . TYR D 2 22  ? -5.012  -13.190 -72.774  1.00 122.79 ? 22  TYR D CE1 1 
ATOM   6667  C CE2 . TYR D 2 22  ? -4.223  -11.002 -73.338  1.00 123.54 ? 22  TYR D CE2 1 
ATOM   6668  C CZ  . TYR D 2 22  ? -5.016  -11.827 -72.567  1.00 120.19 ? 22  TYR D CZ  1 
ATOM   6669  O OH  . TYR D 2 22  ? -5.816  -11.287 -71.587  1.00 118.32 ? 22  TYR D OH  1 
ATOM   6670  N N   . GLY D 2 23  ? -0.954  -16.217 -76.984  1.00 142.05 ? 23  GLY D N   1 
ATOM   6671  C CA  . GLY D 2 23  ? 0.045   -16.674 -77.927  1.00 146.65 ? 23  GLY D CA  1 
ATOM   6672  C C   . GLY D 2 23  ? -0.501  -17.430 -79.120  1.00 149.15 ? 23  GLY D C   1 
ATOM   6673  O O   . GLY D 2 23  ? -1.690  -17.336 -79.441  1.00 142.98 ? 23  GLY D O   1 
ATOM   6674  N N   . TYR D 2 24  ? 0.372   -18.183 -79.787  1.00 152.03 ? 24  TYR D N   1 
ATOM   6675  C CA  . TYR D 2 24  ? 0.011   -18.941 -80.975  1.00 142.51 ? 24  TYR D CA  1 
ATOM   6676  C C   . TYR D 2 24  ? 0.632   -20.328 -80.893  1.00 147.11 ? 24  TYR D C   1 
ATOM   6677  O O   . TYR D 2 24  ? 1.614   -20.550 -80.181  1.00 151.58 ? 24  TYR D O   1 
ATOM   6678  C CB  . TYR D 2 24  ? 0.480   -18.248 -82.264  1.00 137.47 ? 24  TYR D CB  1 
ATOM   6679  C CG  . TYR D 2 24  ? 0.292   -16.746 -82.292  1.00 134.83 ? 24  TYR D CG  1 
ATOM   6680  C CD1 . TYR D 2 24  ? 1.276   -15.894 -81.807  1.00 134.64 ? 24  TYR D CD1 1 
ATOM   6681  C CD2 . TYR D 2 24  ? -0.859  -16.180 -82.822  1.00 128.62 ? 24  TYR D CD2 1 
ATOM   6682  C CE1 . TYR D 2 24  ? 1.113   -14.522 -81.836  1.00 136.30 ? 24  TYR D CE1 1 
ATOM   6683  C CE2 . TYR D 2 24  ? -1.032  -14.808 -82.856  1.00 123.09 ? 24  TYR D CE2 1 
ATOM   6684  C CZ  . TYR D 2 24  ? -0.043  -13.984 -82.362  1.00 128.42 ? 24  TYR D CZ  1 
ATOM   6685  O OH  . TYR D 2 24  ? -0.209  -12.619 -82.395  1.00 124.91 ? 24  TYR D OH  1 
ATOM   6686  N N   . HIS D 2 25  ? 0.039   -21.264 -81.630  1.00 155.75 ? 25  HIS D N   1 
ATOM   6687  C CA  . HIS D 2 25  ? 0.618   -22.583 -81.859  1.00 160.48 ? 25  HIS D CA  1 
ATOM   6688  C C   . HIS D 2 25  ? 0.749   -22.785 -83.360  1.00 170.69 ? 25  HIS D C   1 
ATOM   6689  O O   . HIS D 2 25  ? -0.240  -22.669 -84.092  1.00 172.63 ? 25  HIS D O   1 
ATOM   6690  C CB  . HIS D 2 25  ? -0.238  -23.691 -81.241  1.00 155.45 ? 25  HIS D CB  1 
ATOM   6691  C CG  . HIS D 2 25  ? 0.215   -25.074 -81.595  1.00 159.00 ? 25  HIS D CG  1 
ATOM   6692  N ND1 . HIS D 2 25  ? 1.304   -25.676 -81.001  1.00 159.55 ? 25  HIS D ND1 1 
ATOM   6693  C CD2 . HIS D 2 25  ? -0.274  -25.973 -82.481  1.00 156.99 ? 25  HIS D CD2 1 
ATOM   6694  C CE1 . HIS D 2 25  ? 1.466   -26.886 -81.506  1.00 157.11 ? 25  HIS D CE1 1 
ATOM   6695  N NE2 . HIS D 2 25  ? 0.521   -27.091 -82.407  1.00 157.22 ? 25  HIS D NE2 1 
ATOM   6696  N N   . HIS D 2 26  ? 1.961   -23.087 -83.815  1.00 173.16 ? 26  HIS D N   1 
ATOM   6697  C CA  . HIS D 2 26  ? 2.248   -23.228 -85.234  1.00 172.89 ? 26  HIS D CA  1 
ATOM   6698  C C   . HIS D 2 26  ? 2.683   -24.654 -85.534  1.00 172.33 ? 26  HIS D C   1 
ATOM   6699  O O   . HIS D 2 26  ? 3.354   -25.295 -84.718  1.00 168.66 ? 26  HIS D O   1 
ATOM   6700  C CB  . HIS D 2 26  ? 3.336   -22.244 -85.681  1.00 165.16 ? 26  HIS D CB  1 
ATOM   6701  C CG  . HIS D 2 26  ? 4.715   -22.617 -85.231  1.00 167.53 ? 26  HIS D CG  1 
ATOM   6702  N ND1 . HIS D 2 26  ? 5.501   -23.522 -85.913  1.00 172.15 ? 26  HIS D ND1 1 
ATOM   6703  C CD2 . HIS D 2 26  ? 5.453   -22.199 -84.175  1.00 164.55 ? 26  HIS D CD2 1 
ATOM   6704  C CE1 . HIS D 2 26  ? 6.661   -23.650 -85.293  1.00 166.30 ? 26  HIS D CE1 1 
ATOM   6705  N NE2 . HIS D 2 26  ? 6.657   -22.858 -84.235  1.00 160.04 ? 26  HIS D NE2 1 
ATOM   6706  N N   . SER D 2 27  ? 2.290   -25.148 -86.708  1.00 182.11 ? 27  SER D N   1 
ATOM   6707  C CA  . SER D 2 27  ? 2.714   -26.466 -87.186  1.00 183.17 ? 27  SER D CA  1 
ATOM   6708  C C   . SER D 2 27  ? 3.019   -26.337 -88.678  1.00 189.14 ? 27  SER D C   1 
ATOM   6709  O O   . SER D 2 27  ? 2.140   -26.526 -89.522  1.00 195.67 ? 27  SER D O   1 
ATOM   6710  C CB  . SER D 2 27  ? 1.653   -27.525 -86.914  1.00 173.26 ? 27  SER D CB  1 
ATOM   6711  O OG  . SER D 2 27  ? 2.104   -28.808 -87.310  1.00 166.41 ? 27  SER D OG  1 
ATOM   6712  N N   . ASN D 2 28  ? 4.269   -26.013 -88.992  1.00 186.43 ? 28  ASN D N   1 
ATOM   6713  C CA  . ASN D 2 28  ? 4.759   -26.007 -90.359  1.00 179.20 ? 28  ASN D CA  1 
ATOM   6714  C C   . ASN D 2 28  ? 5.802   -27.112 -90.511  1.00 176.51 ? 28  ASN D C   1 
ATOM   6715  O O   . ASN D 2 28  ? 6.014   -27.926 -89.604  1.00 169.97 ? 28  ASN D O   1 
ATOM   6716  C CB  . ASN D 2 28  ? 5.303   -24.623 -90.736  1.00 172.69 ? 28  ASN D CB  1 
ATOM   6717  C CG  . ASN D 2 28  ? 6.618   -24.295 -90.053  1.00 169.85 ? 28  ASN D CG  1 
ATOM   6718  O OD1 . ASN D 2 28  ? 6.919   -24.802 -88.973  1.00 172.55 ? 28  ASN D OD1 1 
ATOM   6719  N ND2 . ASN D 2 28  ? 7.407   -23.430 -90.683  1.00 155.98 ? 28  ASN D ND2 1 
ATOM   6720  N N   . GLU D 2 29  ? 6.448   -27.151 -91.676  1.00 176.31 ? 29  GLU D N   1 
ATOM   6721  C CA  . GLU D 2 29  ? 7.370   -28.242 -91.973  1.00 160.07 ? 29  GLU D CA  1 
ATOM   6722  C C   . GLU D 2 29  ? 8.585   -28.225 -91.051  1.00 158.33 ? 29  GLU D C   1 
ATOM   6723  O O   . GLU D 2 29  ? 9.084   -29.285 -90.655  1.00 144.76 ? 29  GLU D O   1 
ATOM   6724  C CB  . GLU D 2 29  ? 7.802   -28.174 -93.437  1.00 147.62 ? 29  GLU D CB  1 
ATOM   6725  C CG  . GLU D 2 29  ? 8.541   -26.900 -93.840  1.00 157.46 ? 29  GLU D CG  1 
ATOM   6726  C CD  . GLU D 2 29  ? 7.609   -25.755 -94.195  1.00 172.57 ? 29  GLU D CD  1 
ATOM   6727  O OE1 . GLU D 2 29  ? 6.395   -25.861 -93.920  1.00 173.15 ? 29  GLU D OE1 1 
ATOM   6728  O OE2 . GLU D 2 29  ? 8.093   -24.749 -94.756  1.00 176.81 ? 29  GLU D OE2 1 
ATOM   6729  N N   . GLN D 2 30  ? 9.073   -27.035 -90.696  1.00 169.07 ? 30  GLN D N   1 
ATOM   6730  C CA  . GLN D 2 30  ? 10.324  -26.912 -89.957  1.00 167.00 ? 30  GLN D CA  1 
ATOM   6731  C C   . GLN D 2 30  ? 10.206  -27.331 -88.496  1.00 172.27 ? 30  GLN D C   1 
ATOM   6732  O O   . GLN D 2 30  ? 11.236  -27.457 -87.825  1.00 171.72 ? 30  GLN D O   1 
ATOM   6733  C CB  . GLN D 2 30  ? 10.835  -25.474 -90.049  1.00 163.87 ? 30  GLN D CB  1 
ATOM   6734  C CG  . GLN D 2 30  ? 10.862  -24.931 -91.470  1.00 159.41 ? 30  GLN D CG  1 
ATOM   6735  C CD  . GLN D 2 30  ? 11.347  -23.497 -91.541  1.00 164.81 ? 30  GLN D CD  1 
ATOM   6736  O OE1 . GLN D 2 30  ? 10.804  -22.683 -92.288  1.00 169.03 ? 30  GLN D OE1 1 
ATOM   6737  N NE2 . GLN D 2 30  ? 12.377  -23.181 -90.765  1.00 162.17 ? 30  GLN D NE2 1 
ATOM   6738  N N   . GLY D 2 31  ? 8.999   -27.544 -87.990  1.00 169.21 ? 31  GLY D N   1 
ATOM   6739  C CA  . GLY D 2 31  ? 8.839   -27.973 -86.608  1.00 159.35 ? 31  GLY D CA  1 
ATOM   6740  C C   . GLY D 2 31  ? 7.443   -27.646 -86.100  1.00 165.68 ? 31  GLY D C   1 
ATOM   6741  O O   . GLY D 2 31  ? 6.492   -27.555 -86.877  1.00 168.45 ? 31  GLY D O   1 
ATOM   6742  N N   . SER D 2 32  ? 7.351   -27.479 -84.782  1.00 165.73 ? 32  SER D N   1 
ATOM   6743  C CA  . SER D 2 32  ? 6.086   -27.145 -84.130  1.00 165.15 ? 32  SER D CA  1 
ATOM   6744  C C   . SER D 2 32  ? 6.397   -26.547 -82.769  1.00 161.72 ? 32  SER D C   1 
ATOM   6745  O O   . SER D 2 32  ? 7.075   -27.185 -81.956  1.00 150.00 ? 32  SER D O   1 
ATOM   6746  C CB  . SER D 2 32  ? 5.194   -28.381 -83.989  1.00 158.00 ? 32  SER D CB  1 
ATOM   6747  O OG  . SER D 2 32  ? 4.811   -28.889 -85.255  1.00 159.68 ? 32  SER D OG  1 
ATOM   6748  N N   . GLY D 2 33  ? 5.908   -25.335 -82.516  1.00 165.40 ? 33  GLY D N   1 
ATOM   6749  C CA  . GLY D 2 33  ? 6.198   -24.667 -81.263  1.00 163.43 ? 33  GLY D CA  1 
ATOM   6750  C C   . GLY D 2 33  ? 5.166   -23.607 -80.945  1.00 163.32 ? 33  GLY D C   1 
ATOM   6751  O O   . GLY D 2 33  ? 4.179   -23.428 -81.662  1.00 159.22 ? 33  GLY D O   1 
ATOM   6752  N N   . TYR D 2 34  ? 5.412   -22.902 -79.842  1.00 162.48 ? 34  TYR D N   1 
ATOM   6753  C CA  . TYR D 2 34  ? 4.542   -21.839 -79.363  1.00 149.98 ? 34  TYR D CA  1 
ATOM   6754  C C   . TYR D 2 34  ? 5.283   -20.508 -79.380  1.00 142.21 ? 34  TYR D C   1 
ATOM   6755  O O   . TYR D 2 34  ? 6.516   -20.459 -79.411  1.00 152.72 ? 34  TYR D O   1 
ATOM   6756  C CB  . TYR D 2 34  ? 4.040   -22.124 -77.940  1.00 143.67 ? 34  TYR D CB  1 
ATOM   6757  C CG  . TYR D 2 34  ? 3.338   -23.453 -77.769  1.00 148.69 ? 34  TYR D CG  1 
ATOM   6758  C CD1 . TYR D 2 34  ? 1.975   -23.576 -78.005  1.00 150.63 ? 34  TYR D CD1 1 
ATOM   6759  C CD2 . TYR D 2 34  ? 4.036   -24.581 -77.357  1.00 143.86 ? 34  TYR D CD2 1 
ATOM   6760  C CE1 . TYR D 2 34  ? 1.328   -24.788 -77.844  1.00 146.75 ? 34  TYR D CE1 1 
ATOM   6761  C CE2 . TYR D 2 34  ? 3.398   -25.796 -77.193  1.00 141.35 ? 34  TYR D CE2 1 
ATOM   6762  C CZ  . TYR D 2 34  ? 2.045   -25.894 -77.438  1.00 144.56 ? 34  TYR D CZ  1 
ATOM   6763  O OH  . TYR D 2 34  ? 1.406   -27.102 -77.277  1.00 144.58 ? 34  TYR D OH  1 
ATOM   6764  N N   . ALA D 2 35  ? 4.511   -19.423 -79.357  1.00 138.98 ? 35  ALA D N   1 
ATOM   6765  C CA  . ALA D 2 35  ? 5.064   -18.078 -79.297  1.00 146.93 ? 35  ALA D CA  1 
ATOM   6766  C C   . ALA D 2 35  ? 3.968   -17.116 -78.863  1.00 152.87 ? 35  ALA D C   1 
ATOM   6767  O O   . ALA D 2 35  ? 2.838   -17.200 -79.349  1.00 156.70 ? 35  ALA D O   1 
ATOM   6768  C CB  . ALA D 2 35  ? 5.649   -17.647 -80.647  1.00 140.80 ? 35  ALA D CB  1 
ATOM   6769  N N   . ALA D 2 36  ? 4.311   -16.204 -77.959  1.00 143.87 ? 36  ALA D N   1 
ATOM   6770  C CA  . ALA D 2 36  ? 3.364   -15.246 -77.408  1.00 135.47 ? 36  ALA D CA  1 
ATOM   6771  C C   . ALA D 2 36  ? 3.422   -13.922 -78.161  1.00 139.40 ? 36  ALA D C   1 
ATOM   6772  O O   . ALA D 2 36  ? 4.411   -13.594 -78.823  1.00 138.61 ? 36  ALA D O   1 
ATOM   6773  C CB  . ALA D 2 36  ? 3.640   -15.005 -75.922  1.00 131.57 ? 36  ALA D CB  1 
ATOM   6774  N N   . ASP D 2 37  ? 2.337   -13.160 -78.051  1.00 136.89 ? 37  ASP D N   1 
ATOM   6775  C CA  . ASP D 2 37  ? 2.278   -11.805 -78.581  1.00 137.28 ? 37  ASP D CA  1 
ATOM   6776  C C   . ASP D 2 37  ? 2.662   -10.834 -77.471  1.00 136.81 ? 37  ASP D C   1 
ATOM   6777  O O   . ASP D 2 37  ? 1.971   -10.747 -76.451  1.00 131.63 ? 37  ASP D O   1 
ATOM   6778  C CB  . ASP D 2 37  ? 0.882   -11.491 -79.120  1.00 133.73 ? 37  ASP D CB  1 
ATOM   6779  C CG  . ASP D 2 37  ? 0.802   -10.126 -79.779  1.00 136.14 ? 37  ASP D CG  1 
ATOM   6780  O OD1 . ASP D 2 37  ? 1.864   -9.549  -80.094  1.00 134.97 ? 37  ASP D OD1 1 
ATOM   6781  O OD2 . ASP D 2 37  ? -0.325  -9.626  -79.978  1.00 132.56 ? 37  ASP D OD2 1 
ATOM   6782  N N   . LYS D 2 38  ? 3.765   -10.109 -77.670  1.00 138.75 ? 38  LYS D N   1 
ATOM   6783  C CA  . LYS D 2 38  ? 4.268   -9.229  -76.620  1.00 138.86 ? 38  LYS D CA  1 
ATOM   6784  C C   . LYS D 2 38  ? 3.283   -8.105  -76.317  1.00 135.46 ? 38  LYS D C   1 
ATOM   6785  O O   . LYS D 2 38  ? 3.060   -7.763  -75.150  1.00 136.29 ? 38  LYS D O   1 
ATOM   6786  C CB  . LYS D 2 38  ? 5.632   -8.663  -77.022  1.00 137.81 ? 38  LYS D CB  1 
ATOM   6787  C CG  . LYS D 2 38  ? 6.514   -8.228  -75.851  1.00 140.84 ? 38  LYS D CG  1 
ATOM   6788  C CD  . LYS D 2 38  ? 6.160   -6.835  -75.350  1.00 138.80 ? 38  LYS D CD  1 
ATOM   6789  C CE  . LYS D 2 38  ? 6.832   -6.533  -74.021  1.00 122.74 ? 38  LYS D CE  1 
ATOM   6790  N NZ  . LYS D 2 38  ? 6.414   -5.209  -73.484  1.00 121.91 ? 38  LYS D NZ  1 
ATOM   6791  N N   . GLU D 2 39  ? 2.681   -7.519  -77.354  1.00 136.00 ? 39  GLU D N   1 
ATOM   6792  C CA  . GLU D 2 39  ? 1.821   -6.358  -77.144  1.00 136.97 ? 39  GLU D CA  1 
ATOM   6793  C C   . GLU D 2 39  ? 0.503   -6.744  -76.482  1.00 137.42 ? 39  GLU D C   1 
ATOM   6794  O O   . GLU D 2 39  ? 0.013   -6.026  -75.602  1.00 133.75 ? 39  GLU D O   1 
ATOM   6795  C CB  . GLU D 2 39  ? 1.571   -5.645  -78.473  1.00 131.88 ? 39  GLU D CB  1 
ATOM   6796  C CG  . GLU D 2 39  ? 0.701   -4.404  -78.357  1.00 132.36 ? 39  GLU D CG  1 
ATOM   6797  C CD  . GLU D 2 39  ? 0.825   -3.492  -79.560  1.00 136.15 ? 39  GLU D CD  1 
ATOM   6798  O OE1 . GLU D 2 39  ? 1.856   -3.569  -80.261  1.00 149.86 ? 39  GLU D OE1 1 
ATOM   6799  O OE2 . GLU D 2 39  ? -0.107  -2.697  -79.807  1.00 119.14 ? 39  GLU D OE2 1 
ATOM   6800  N N   . SER D 2 40  ? -0.091  -7.869  -76.892  1.00 138.13 ? 40  SER D N   1 
ATOM   6801  C CA  . SER D 2 40  ? -1.392  -8.253  -76.351  1.00 135.65 ? 40  SER D CA  1 
ATOM   6802  C C   . SER D 2 40  ? -1.301  -8.618  -74.873  1.00 132.88 ? 40  SER D C   1 
ATOM   6803  O O   . SER D 2 40  ? -2.173  -8.240  -74.082  1.00 133.31 ? 40  SER D O   1 
ATOM   6804  C CB  . SER D 2 40  ? -1.978  -9.415  -77.154  1.00 131.86 ? 40  SER D CB  1 
ATOM   6805  O OG  . SER D 2 40  ? -1.277  -10.618 -76.897  1.00 137.62 ? 40  SER D OG  1 
ATOM   6806  N N   . THR D 2 41  ? -0.259  -9.356  -74.482  1.00 128.23 ? 41  THR D N   1 
ATOM   6807  C CA  . THR D 2 41  ? -0.131  -9.763  -73.085  1.00 123.95 ? 41  THR D CA  1 
ATOM   6808  C C   . THR D 2 41  ? 0.245   -8.586  -72.195  1.00 116.77 ? 41  THR D C   1 
ATOM   6809  O O   . THR D 2 41  ? -0.326  -8.414  -71.112  1.00 117.04 ? 41  THR D O   1 
ATOM   6810  C CB  . THR D 2 41  ? 0.905   -10.877 -72.947  1.00 121.08 ? 41  THR D CB  1 
ATOM   6811  O OG1 . THR D 2 41  ? 2.204   -10.365 -73.269  1.00 131.01 ? 41  THR D OG1 1 
ATOM   6812  C CG2 . THR D 2 41  ? 0.577   -12.022 -73.879  1.00 124.47 ? 41  THR D CG2 1 
ATOM   6813  N N   . GLN D 2 42  ? 1.204   -7.766  -72.634  1.00 115.86 ? 42  GLN D N   1 
ATOM   6814  C CA  . GLN D 2 42  ? 1.641   -6.640  -71.816  1.00 117.42 ? 42  GLN D CA  1 
ATOM   6815  C C   . GLN D 2 42  ? 0.512   -5.645  -71.588  1.00 117.42 ? 42  GLN D C   1 
ATOM   6816  O O   . GLN D 2 42  ? 0.482   -4.966  -70.556  1.00 114.19 ? 42  GLN D O   1 
ATOM   6817  C CB  . GLN D 2 42  ? 2.840   -5.950  -72.467  1.00 127.08 ? 42  GLN D CB  1 
ATOM   6818  C CG  . GLN D 2 42  ? 3.628   -5.057  -71.522  1.00 125.30 ? 42  GLN D CG  1 
ATOM   6819  C CD  . GLN D 2 42  ? 4.300   -5.838  -70.408  1.00 118.66 ? 42  GLN D CD  1 
ATOM   6820  O OE1 . GLN D 2 42  ? 4.644   -7.009  -70.575  1.00 115.72 ? 42  GLN D OE1 1 
ATOM   6821  N NE2 . GLN D 2 42  ? 4.485   -5.193  -69.263  1.00 120.27 ? 42  GLN D NE2 1 
ATOM   6822  N N   . LYS D 2 43  ? -0.423  -5.544  -72.535  1.00 118.33 ? 43  LYS D N   1 
ATOM   6823  C CA  . LYS D 2 43  ? -1.598  -4.708  -72.325  1.00 117.03 ? 43  LYS D CA  1 
ATOM   6824  C C   . LYS D 2 43  ? -2.573  -5.336  -71.338  1.00 113.19 ? 43  LYS D C   1 
ATOM   6825  O O   . LYS D 2 43  ? -3.382  -4.617  -70.740  1.00 110.43 ? 43  LYS D O   1 
ATOM   6826  C CB  . LYS D 2 43  ? -2.292  -4.435  -73.662  1.00 118.48 ? 43  LYS D CB  1 
ATOM   6827  C CG  . LYS D 2 43  ? -3.279  -3.278  -73.631  1.00 112.40 ? 43  LYS D CG  1 
ATOM   6828  C CD  . LYS D 2 43  ? -2.629  -2.016  -73.082  1.00 119.79 ? 43  LYS D CD  1 
ATOM   6829  C CE  . LYS D 2 43  ? -1.471  -1.553  -73.954  1.00 113.12 ? 43  LYS D CE  1 
ATOM   6830  N NZ  . LYS D 2 43  ? -0.687  -0.470  -73.298  1.00 120.98 ? 43  LYS D NZ  1 
ATOM   6831  N N   . ALA D 2 44  ? -2.511  -6.654  -71.151  1.00 107.19 ? 44  ALA D N   1 
ATOM   6832  C CA  . ALA D 2 44  ? -3.335  -7.333  -70.160  1.00 100.12 ? 44  ALA D CA  1 
ATOM   6833  C C   . ALA D 2 44  ? -2.685  -7.341  -68.783  1.00 105.86 ? 44  ALA D C   1 
ATOM   6834  O O   . ALA D 2 44  ? -3.381  -7.200  -67.772  1.00 108.56 ? 44  ALA D O   1 
ATOM   6835  C CB  . ALA D 2 44  ? -3.627  -8.767  -70.607  1.00 99.74  ? 44  ALA D CB  1 
ATOM   6836  N N   . ILE D 2 45  ? -1.362  -7.513  -68.723  1.00 110.52 ? 45  ILE D N   1 
ATOM   6837  C CA  . ILE D 2 45  ? -0.659  -7.419  -67.445  1.00 101.60 ? 45  ILE D CA  1 
ATOM   6838  C C   . ILE D 2 45  ? -0.806  -6.016  -66.871  1.00 99.41  ? 45  ILE D C   1 
ATOM   6839  O O   . ILE D 2 45  ? -1.101  -5.838  -65.684  1.00 102.10 ? 45  ILE D O   1 
ATOM   6840  C CB  . ILE D 2 45  ? 0.823   -7.803  -67.612  1.00 107.79 ? 45  ILE D CB  1 
ATOM   6841  C CG1 . ILE D 2 45  ? 0.962   -9.170  -68.290  1.00 110.00 ? 45  ILE D CG1 1 
ATOM   6842  C CG2 . ILE D 2 45  ? 1.528   -7.796  -66.260  1.00 94.84  ? 45  ILE D CG2 1 
ATOM   6843  C CD1 . ILE D 2 45  ? 0.949   -10.348 -67.337  1.00 92.99  ? 45  ILE D CD1 1 
ATOM   6844  N N   . ASP D 2 46  ? -0.610  -4.996  -67.711  1.00 103.40 ? 46  ASP D N   1 
ATOM   6845  C CA  . ASP D 2 46  ? -0.789  -3.618  -67.271  1.00 108.01 ? 46  ASP D CA  1 
ATOM   6846  C C   . ASP D 2 46  ? -2.243  -3.296  -66.956  1.00 106.51 ? 46  ASP D C   1 
ATOM   6847  O O   . ASP D 2 46  ? -2.506  -2.361  -66.192  1.00 100.98 ? 46  ASP D O   1 
ATOM   6848  C CB  . ASP D 2 46  ? -0.263  -2.648  -68.331  1.00 110.54 ? 46  ASP D CB  1 
ATOM   6849  C CG  . ASP D 2 46  ? 1.234   -2.768  -68.542  1.00 121.68 ? 46  ASP D CG  1 
ATOM   6850  O OD1 . ASP D 2 46  ? 1.855   -3.658  -67.924  1.00 112.95 ? 46  ASP D OD1 1 
ATOM   6851  O OD2 . ASP D 2 46  ? 1.790   -1.970  -69.327  1.00 129.69 ? 46  ASP D OD2 1 
ATOM   6852  N N   . GLY D 2 47  ? -3.188  -4.039  -67.527  1.00 97.52  ? 47  GLY D N   1 
ATOM   6853  C CA  . GLY D 2 47  ? -4.593  -3.822  -67.247  1.00 91.04  ? 47  GLY D CA  1 
ATOM   6854  C C   . GLY D 2 47  ? -5.020  -4.396  -65.912  1.00 93.45  ? 47  GLY D C   1 
ATOM   6855  O O   . GLY D 2 47  ? -5.635  -3.701  -65.098  1.00 79.36  ? 47  GLY D O   1 
ATOM   6856  N N   . VAL D 2 48  ? -4.697  -5.670  -65.675  1.00 86.06  ? 48  VAL D N   1 
ATOM   6857  C CA  . VAL D 2 48  ? -5.069  -6.300  -64.412  1.00 99.06  ? 48  VAL D CA  1 
ATOM   6858  C C   . VAL D 2 48  ? -4.271  -5.710  -63.254  1.00 101.96 ? 48  VAL D C   1 
ATOM   6859  O O   . VAL D 2 48  ? -4.766  -5.649  -62.122  1.00 100.45 ? 48  VAL D O   1 
ATOM   6860  C CB  . VAL D 2 48  ? -4.906  -7.830  -64.499  1.00 97.79  ? 48  VAL D CB  1 
ATOM   6861  C CG1 . VAL D 2 48  ? -5.714  -8.380  -65.666  1.00 92.28  ? 48  VAL D CG1 1 
ATOM   6862  C CG2 . VAL D 2 48  ? -3.441  -8.219  -64.625  1.00 107.71 ? 48  VAL D CG2 1 
ATOM   6863  N N   . THR D 2 49  ? -3.031  -5.278  -63.502  1.00 97.50  ? 49  THR D N   1 
ATOM   6864  C CA  . THR D 2 49  ? -2.256  -4.635  -62.446  1.00 99.89  ? 49  THR D CA  1 
ATOM   6865  C C   . THR D 2 49  ? -2.816  -3.256  -62.119  1.00 95.17  ? 49  THR D C   1 
ATOM   6866  O O   . THR D 2 49  ? -2.841  -2.851  -60.951  1.00 94.88  ? 49  THR D O   1 
ATOM   6867  C CB  . THR D 2 49  ? -0.782  -4.541  -62.848  1.00 94.68  ? 49  THR D CB  1 
ATOM   6868  O OG1 . THR D 2 49  ? -0.279  -5.854  -63.124  1.00 89.46  ? 49  THR D OG1 1 
ATOM   6869  C CG2 . THR D 2 49  ? 0.043   -3.917  -61.732  1.00 81.22  ? 49  THR D CG2 1 
ATOM   6870  N N   . ASN D 2 50  ? -3.278  -2.523  -63.135  1.00 86.69  ? 50  ASN D N   1 
ATOM   6871  C CA  . ASN D 2 50  ? -3.899  -1.228  -62.879  1.00 86.21  ? 50  ASN D CA  1 
ATOM   6872  C C   . ASN D 2 50  ? -5.268  -1.382  -62.229  1.00 90.39  ? 50  ASN D C   1 
ATOM   6873  O O   . ASN D 2 50  ? -5.668  -0.534  -61.423  1.00 97.52  ? 50  ASN D O   1 
ATOM   6874  C CB  . ASN D 2 50  ? -4.014  -0.428  -64.176  1.00 88.81  ? 50  ASN D CB  1 
ATOM   6875  C CG  . ASN D 2 50  ? -4.436  1.009   -63.940  1.00 85.77  ? 50  ASN D CG  1 
ATOM   6876  O OD1 . ASN D 2 50  ? -5.626  1.323   -63.913  1.00 90.40  ? 50  ASN D OD1 1 
ATOM   6877  N ND2 . ASN D 2 50  ? -3.459  1.891   -63.768  1.00 98.32  ? 50  ASN D ND2 1 
ATOM   6878  N N   . LYS D 2 51  ? -6.004  -2.444  -62.569  1.00 87.45  ? 51  LYS D N   1 
ATOM   6879  C CA  . LYS D 2 51  ? -7.281  -2.694  -61.909  1.00 87.61  ? 51  LYS D CA  1 
ATOM   6880  C C   . LYS D 2 51  ? -7.085  -3.025  -60.435  1.00 89.47  ? 51  LYS D C   1 
ATOM   6881  O O   . LYS D 2 51  ? -7.807  -2.505  -59.576  1.00 85.53  ? 51  LYS D O   1 
ATOM   6882  C CB  . LYS D 2 51  ? -8.032  -3.826  -62.609  1.00 84.87  ? 51  LYS D CB  1 
ATOM   6883  C CG  . LYS D 2 51  ? -9.323  -4.213  -61.904  1.00 84.60  ? 51  LYS D CG  1 
ATOM   6884  C CD  . LYS D 2 51  ? -9.865  -5.550  -62.380  1.00 89.17  ? 51  LYS D CD  1 
ATOM   6885  C CE  . LYS D 2 51  ? -10.252 -5.508  -63.846  1.00 96.40  ? 51  LYS D CE  1 
ATOM   6886  N NZ  . LYS D 2 51  ? -11.259 -6.557  -64.167  1.00 89.06  ? 51  LYS D NZ  1 
ATOM   6887  N N   . VAL D 2 52  ? -6.115  -3.887  -60.123  1.00 84.24  ? 52  VAL D N   1 
ATOM   6888  C CA  . VAL D 2 52  ? -5.856  -4.247  -58.732  1.00 84.66  ? 52  VAL D CA  1 
ATOM   6889  C C   . VAL D 2 52  ? -5.379  -3.032  -57.945  1.00 86.81  ? 52  VAL D C   1 
ATOM   6890  O O   . VAL D 2 52  ? -5.804  -2.806  -56.805  1.00 89.94  ? 52  VAL D O   1 
ATOM   6891  C CB  . VAL D 2 52  ? -4.847  -5.409  -58.660  1.00 87.08  ? 52  VAL D CB  1 
ATOM   6892  C CG1 . VAL D 2 52  ? -4.355  -5.607  -57.235  1.00 90.34  ? 52  VAL D CG1 1 
ATOM   6893  C CG2 . VAL D 2 52  ? -5.480  -6.689  -59.181  1.00 78.22  ? 52  VAL D CG2 1 
ATOM   6894  N N   . ASN D 2 53  ? -4.495  -2.229  -58.541  1.00 82.67  ? 53  ASN D N   1 
ATOM   6895  C CA  . ASN D 2 53  ? -3.988  -1.045  -57.852  1.00 82.72  ? 53  ASN D CA  1 
ATOM   6896  C C   . ASN D 2 53  ? -5.087  -0.012  -57.628  1.00 81.26  ? 53  ASN D C   1 
ATOM   6897  O O   . ASN D 2 53  ? -5.119  0.646   -56.581  1.00 88.29  ? 53  ASN D O   1 
ATOM   6898  C CB  . ASN D 2 53  ? -2.828  -0.434  -58.638  1.00 90.60  ? 53  ASN D CB  1 
ATOM   6899  C CG  . ASN D 2 53  ? -1.598  -1.322  -58.646  1.00 97.01  ? 53  ASN D CG  1 
ATOM   6900  O OD1 . ASN D 2 53  ? -1.458  -2.213  -57.808  1.00 72.19  ? 53  ASN D OD1 1 
ATOM   6901  N ND2 . ASN D 2 53  ? -0.699  -1.081  -59.595  1.00 100.49 ? 53  ASN D ND2 1 
ATOM   6902  N N   . SER D 2 54  ? -5.988  0.157   -58.600  1.00 73.40  ? 54  SER D N   1 
ATOM   6903  C CA  . SER D 2 54  ? -7.062  1.135   -58.446  1.00 77.34  ? 54  SER D CA  1 
ATOM   6904  C C   . SER D 2 54  ? -8.006  0.746   -57.314  1.00 75.62  ? 54  SER D C   1 
ATOM   6905  O O   . SER D 2 54  ? -8.512  1.613   -56.593  1.00 80.46  ? 54  SER D O   1 
ATOM   6906  C CB  . SER D 2 54  ? -7.831  1.289   -59.758  1.00 82.19  ? 54  SER D CB  1 
ATOM   6907  O OG  . SER D 2 54  ? -6.997  1.785   -60.789  1.00 89.29  ? 54  SER D OG  1 
ATOM   6908  N N   . ILE D 2 55  ? -8.258  -0.553  -57.146  1.00 72.49  ? 55  ILE D N   1 
ATOM   6909  C CA  . ILE D 2 55  ? -9.081  -1.014  -56.032  1.00 74.13  ? 55  ILE D CA  1 
ATOM   6910  C C   . ILE D 2 55  ? -8.399  -0.714  -54.703  1.00 84.05  ? 55  ILE D C   1 
ATOM   6911  O O   . ILE D 2 55  ? -9.065  -0.399  -53.708  1.00 84.28  ? 55  ILE D O   1 
ATOM   6912  C CB  . ILE D 2 55  ? -9.391  -2.515  -56.191  1.00 77.49  ? 55  ILE D CB  1 
ATOM   6913  C CG1 . ILE D 2 55  ? -10.161 -2.757  -57.491  1.00 77.55  ? 55  ILE D CG1 1 
ATOM   6914  C CG2 . ILE D 2 55  ? -10.190 -3.035  -55.005  1.00 71.99  ? 55  ILE D CG2 1 
ATOM   6915  C CD1 . ILE D 2 55  ? -10.426 -4.213  -57.788  1.00 79.49  ? 55  ILE D CD1 1 
ATOM   6916  N N   . ILE D 2 56  ? -7.069  -0.792  -54.665  1.00 84.11  ? 56  ILE D N   1 
ATOM   6917  C CA  . ILE D 2 56  ? -6.331  -0.576  -53.425  1.00 69.46  ? 56  ILE D CA  1 
ATOM   6918  C C   . ILE D 2 56  ? -6.116  0.911   -53.167  1.00 79.06  ? 56  ILE D C   1 
ATOM   6919  O O   . ILE D 2 56  ? -6.410  1.415   -52.077  1.00 86.80  ? 56  ILE D O   1 
ATOM   6920  C CB  . ILE D 2 56  ? -4.995  -1.341  -53.472  1.00 82.64  ? 56  ILE D CB  1 
ATOM   6921  C CG1 . ILE D 2 56  ? -5.232  -2.835  -53.249  1.00 74.27  ? 56  ILE D CG1 1 
ATOM   6922  C CG2 . ILE D 2 56  ? -4.008  -0.777  -52.456  1.00 71.11  ? 56  ILE D CG2 1 
ATOM   6923  C CD1 . ILE D 2 56  ? -4.102  -3.709  -53.742  1.00 60.69  ? 56  ILE D CD1 1 
ATOM   6924  N N   . ASP D 2 57  ? -5.607  1.639   -54.163  1.00 79.41  ? 57  ASP D N   1 
ATOM   6925  C CA  . ASP D 2 57  ? -5.165  3.011   -53.938  1.00 77.57  ? 57  ASP D CA  1 
ATOM   6926  C C   . ASP D 2 57  ? -6.317  3.993   -53.756  1.00 79.69  ? 57  ASP D C   1 
ATOM   6927  O O   . ASP D 2 57  ? -6.113  5.057   -53.163  1.00 82.98  ? 57  ASP D O   1 
ATOM   6928  C CB  . ASP D 2 57  ? -4.272  3.471   -55.093  1.00 89.26  ? 57  ASP D CB  1 
ATOM   6929  C CG  . ASP D 2 57  ? -2.981  2.676   -55.183  1.00 102.66 ? 57  ASP D CG  1 
ATOM   6930  O OD1 . ASP D 2 57  ? -2.846  1.672   -54.451  1.00 97.16  ? 57  ASP D OD1 1 
ATOM   6931  O OD2 . ASP D 2 57  ? -2.098  3.058   -55.981  1.00 100.12 ? 57  ASP D OD2 1 
ATOM   6932  N N   . LYS D 2 58  ? -7.515  3.673   -54.248  1.00 71.66  ? 58  LYS D N   1 
ATOM   6933  C CA  . LYS D 2 58  ? -8.630  4.606   -54.125  1.00 80.44  ? 58  LYS D CA  1 
ATOM   6934  C C   . LYS D 2 58  ? -9.185  4.693   -52.708  1.00 76.42  ? 58  LYS D C   1 
ATOM   6935  O O   . LYS D 2 58  ? -9.986  5.593   -52.431  1.00 58.75  ? 58  LYS D O   1 
ATOM   6936  C CB  . LYS D 2 58  ? -9.754  4.223   -55.092  1.00 71.48  ? 58  LYS D CB  1 
ATOM   6937  C CG  . LYS D 2 58  ? -9.503  4.634   -56.532  1.00 78.95  ? 58  LYS D CG  1 
ATOM   6938  C CD  . LYS D 2 58  ? -9.359  6.141   -56.660  1.00 68.37  ? 58  LYS D CD  1 
ATOM   6939  C CE  . LYS D 2 58  ? -9.104  6.545   -58.102  1.00 66.69  ? 58  LYS D CE  1 
ATOM   6940  N NZ  . LYS D 2 58  ? -9.044  8.025   -58.268  1.00 62.42  ? 58  LYS D NZ  1 
ATOM   6941  N N   . MET D 2 59  ? -8.783  3.795   -51.811  1.00 70.13  ? 59  MET D N   1 
ATOM   6942  C CA  . MET D 2 59  ? -9.338  3.758   -50.463  1.00 74.33  ? 59  MET D CA  1 
ATOM   6943  C C   . MET D 2 59  ? -8.752  4.899   -49.641  1.00 70.78  ? 59  MET D C   1 
ATOM   6944  O O   . MET D 2 59  ? -7.547  4.925   -49.369  1.00 78.33  ? 59  MET D O   1 
ATOM   6945  C CB  . MET D 2 59  ? -9.058  2.411   -49.803  1.00 73.91  ? 59  MET D CB  1 
ATOM   6946  C CG  . MET D 2 59  ? -9.617  2.276   -48.391  1.00 69.74  ? 59  MET D CG  1 
ATOM   6947  S SD  . MET D 2 59  ? -11.415 2.101   -48.338  1.00 76.77  ? 59  MET D SD  1 
ATOM   6948  C CE  . MET D 2 59  ? -11.957 3.804   -48.180  1.00 78.33  ? 59  MET D CE  1 
ATOM   6949  N N   . ASN D 2 60  ? -9.603  5.835   -49.232  1.00 70.52  ? 60  ASN D N   1 
ATOM   6950  C CA  . ASN D 2 60  ? -9.190  6.882   -48.311  1.00 75.04  ? 60  ASN D CA  1 
ATOM   6951  C C   . ASN D 2 60  ? -9.124  6.317   -46.898  1.00 67.94  ? 60  ASN D C   1 
ATOM   6952  O O   . ASN D 2 60  ? -10.096 5.736   -46.406  1.00 67.15  ? 60  ASN D O   1 
ATOM   6953  C CB  . ASN D 2 60  ? -10.163 8.060   -48.365  1.00 76.54  ? 60  ASN D CB  1 
ATOM   6954  C CG  . ASN D 2 60  ? -9.711  9.227   -47.510  1.00 73.83  ? 60  ASN D CG  1 
ATOM   6955  O OD1 . ASN D 2 60  ? -8.531  9.576   -47.490  1.00 80.77  ? 60  ASN D OD1 1 
ATOM   6956  N ND2 . ASN D 2 60  ? -10.647 9.829   -46.787  1.00 75.05  ? 60  ASN D ND2 1 
ATOM   6957  N N   . THR D 2 61  ? -7.977  6.484   -46.249  1.00 71.32  ? 61  THR D N   1 
ATOM   6958  C CA  . THR D 2 61  ? -7.769  6.011   -44.888  1.00 72.01  ? 61  THR D CA  1 
ATOM   6959  C C   . THR D 2 61  ? -7.385  7.188   -44.005  1.00 68.03  ? 61  THR D C   1 
ATOM   6960  O O   . THR D 2 61  ? -6.506  7.978   -44.363  1.00 78.87  ? 61  THR D O   1 
ATOM   6961  C CB  . THR D 2 61  ? -6.690  4.926   -44.833  1.00 75.69  ? 61  THR D CB  1 
ATOM   6962  O OG1 . THR D 2 61  ? -5.625  5.259   -45.732  1.00 96.30  ? 61  THR D OG1 1 
ATOM   6963  C CG2 . THR D 2 61  ? -7.273  3.573   -45.217  1.00 73.82  ? 61  THR D CG2 1 
ATOM   6964  N N   . GLN D 2 62  ? -8.047  7.301   -42.858  1.00 73.48  ? 62  GLN D N   1 
ATOM   6965  C CA  . GLN D 2 62  ? -7.808  8.375   -41.910  1.00 62.51  ? 62  GLN D CA  1 
ATOM   6966  C C   . GLN D 2 62  ? -7.476  7.789   -40.546  1.00 56.93  ? 62  GLN D C   1 
ATOM   6967  O O   . GLN D 2 62  ? -7.841  6.653   -40.228  1.00 56.80  ? 62  GLN D O   1 
ATOM   6968  C CB  . GLN D 2 62  ? -9.027  9.299   -41.784  1.00 66.40  ? 62  GLN D CB  1 
ATOM   6969  C CG  . GLN D 2 62  ? -9.795  9.515   -43.075  1.00 71.76  ? 62  GLN D CG  1 
ATOM   6970  C CD  . GLN D 2 62  ? -10.966 10.460  -42.899  1.00 65.09  ? 62  GLN D CD  1 
ATOM   6971  O OE1 . GLN D 2 62  ? -10.865 11.469  -42.199  1.00 67.30  ? 62  GLN D OE1 1 
ATOM   6972  N NE2 . GLN D 2 62  ? -12.089 10.136  -43.531  1.00 63.84  ? 62  GLN D NE2 1 
ATOM   6973  N N   . PHE D 2 63  ? -6.774  8.581   -39.741  1.00 54.79  ? 63  PHE D N   1 
ATOM   6974  C CA  . PHE D 2 63  ? -6.497  8.186   -38.368  1.00 57.06  ? 63  PHE D CA  1 
ATOM   6975  C C   . PHE D 2 63  ? -7.797  8.108   -37.579  1.00 61.58  ? 63  PHE D C   1 
ATOM   6976  O O   . PHE D 2 63  ? -8.589  9.055   -37.570  1.00 58.48  ? 63  PHE D O   1 
ATOM   6977  C CB  . PHE D 2 63  ? -5.537  9.185   -37.717  1.00 52.37  ? 63  PHE D CB  1 
ATOM   6978  C CG  . PHE D 2 63  ? -5.148  8.829   -36.306  1.00 57.62  ? 63  PHE D CG  1 
ATOM   6979  C CD1 . PHE D 2 63  ? -5.947  9.199   -35.234  1.00 54.42  ? 63  PHE D CD1 1 
ATOM   6980  C CD2 . PHE D 2 63  ? -3.975  8.136   -36.052  1.00 55.28  ? 63  PHE D CD2 1 
ATOM   6981  C CE1 . PHE D 2 63  ? -5.589  8.871   -33.937  1.00 64.74  ? 63  PHE D CE1 1 
ATOM   6982  C CE2 . PHE D 2 63  ? -3.611  7.809   -34.759  1.00 61.66  ? 63  PHE D CE2 1 
ATOM   6983  C CZ  . PHE D 2 63  ? -4.420  8.176   -33.700  1.00 57.43  ? 63  PHE D CZ  1 
ATOM   6984  N N   . GLU D 2 64  ? -8.018  6.973   -36.919  1.00 55.77  ? 64  GLU D N   1 
ATOM   6985  C CA  . GLU D 2 64  ? -9.173  6.787   -36.053  1.00 60.20  ? 64  GLU D CA  1 
ATOM   6986  C C   . GLU D 2 64  ? -8.740  6.043   -34.801  1.00 56.85  ? 64  GLU D C   1 
ATOM   6987  O O   . GLU D 2 64  ? -7.898  5.143   -34.866  1.00 53.16  ? 64  GLU D O   1 
ATOM   6988  C CB  . GLU D 2 64  ? -10.300 6.009   -36.752  1.00 62.39  ? 64  GLU D CB  1 
ATOM   6989  C CG  . GLU D 2 64  ? -10.848 6.652   -38.022  1.00 64.29  ? 64  GLU D CG  1 
ATOM   6990  C CD  . GLU D 2 64  ? -11.439 8.032   -37.788  1.00 72.71  ? 64  GLU D CD  1 
ATOM   6991  O OE1 . GLU D 2 64  ? -11.297 8.895   -38.680  1.00 69.78  ? 64  GLU D OE1 1 
ATOM   6992  O OE2 . GLU D 2 64  ? -12.044 8.256   -36.718  1.00 86.88  ? 64  GLU D OE2 1 
ATOM   6993  N N   . ALA D 2 65  ? -9.318  6.418   -33.665  1.00 53.82  ? 65  ALA D N   1 
ATOM   6994  C CA  . ALA D 2 65  ? -9.057  5.762   -32.385  1.00 60.37  ? 65  ALA D CA  1 
ATOM   6995  C C   . ALA D 2 65  ? -10.369 5.154   -31.901  1.00 48.35  ? 65  ALA D C   1 
ATOM   6996  O O   . ALA D 2 65  ? -11.244 5.867   -31.400  1.00 53.13  ? 65  ALA D O   1 
ATOM   6997  C CB  . ALA D 2 65  ? -8.484  6.746   -31.370  1.00 47.52  ? 65  ALA D CB  1 
ATOM   6998  N N   . VAL D 2 66  ? -10.502 3.838   -32.042  1.00 52.30  ? 66  VAL D N   1 
ATOM   6999  C CA  . VAL D 2 66  ? -11.744 3.135   -31.740  1.00 50.43  ? 66  VAL D CA  1 
ATOM   7000  C C   . VAL D 2 66  ? -11.606 2.463   -30.383  1.00 50.45  ? 66  VAL D C   1 
ATOM   7001  O O   . VAL D 2 66  ? -10.780 1.559   -30.207  1.00 55.74  ? 66  VAL D O   1 
ATOM   7002  C CB  . VAL D 2 66  ? -12.087 2.109   -32.832  1.00 53.27  ? 66  VAL D CB  1 
ATOM   7003  C CG1 . VAL D 2 66  ? -13.297 1.291   -32.419  1.00 48.59  ? 66  VAL D CG1 1 
ATOM   7004  C CG2 . VAL D 2 66  ? -12.343 2.812   -34.155  1.00 46.23  ? 66  VAL D CG2 1 
ATOM   7005  N N   . GLY D 2 67  ? -12.419 2.898   -29.425  1.00 59.92  ? 67  GLY D N   1 
ATOM   7006  C CA  . GLY D 2 67  ? -12.414 2.314   -28.099  1.00 46.41  ? 67  GLY D CA  1 
ATOM   7007  C C   . GLY D 2 67  ? -13.806 2.158   -27.525  1.00 52.36  ? 67  GLY D C   1 
ATOM   7008  O O   . GLY D 2 67  ? -14.801 2.284   -28.246  1.00 57.15  ? 67  GLY D O   1 
ATOM   7009  N N   . ARG D 2 68  ? -13.888 1.874   -26.226  1.00 52.72  ? 68  ARG D N   1 
ATOM   7010  C CA  . ARG D 2 68  ? -15.154 1.750   -25.500  1.00 46.58  ? 68  ARG D CA  1 
ATOM   7011  C C   . ARG D 2 68  ? -15.052 2.678   -24.293  1.00 48.25  ? 68  ARG D C   1 
ATOM   7012  O O   . ARG D 2 68  ? -14.642 2.254   -23.209  1.00 50.49  ? 68  ARG D O   1 
ATOM   7013  C CB  . ARG D 2 68  ? -15.417 0.302   -25.091  1.00 53.26  ? 68  ARG D CB  1 
ATOM   7014  C CG  . ARG D 2 68  ? -15.622 -0.651  -26.262  1.00 55.72  ? 68  ARG D CG  1 
ATOM   7015  C CD  . ARG D 2 68  ? -16.946 -0.380  -26.961  1.00 67.29  ? 68  ARG D CD  1 
ATOM   7016  N NE  . ARG D 2 68  ? -17.184 -1.289  -28.076  1.00 69.39  ? 68  ARG D NE  1 
ATOM   7017  C CZ  . ARG D 2 68  ? -16.929 -1.002  -29.345  1.00 60.79  ? 68  ARG D CZ  1 
ATOM   7018  N NH1 . ARG D 2 68  ? -16.420 0.167   -29.701  1.00 51.78  ? 68  ARG D NH1 1 
ATOM   7019  N NH2 . ARG D 2 68  ? -17.196 -1.908  -30.281  1.00 51.35  ? 68  ARG D NH2 1 
ATOM   7020  N N   . GLU D 2 69  ? -15.431 3.942   -24.482  1.00 56.39  ? 69  GLU D N   1 
ATOM   7021  C CA  . GLU D 2 69  ? -15.158 4.990   -23.507  1.00 51.94  ? 69  GLU D CA  1 
ATOM   7022  C C   . GLU D 2 69  ? -16.394 5.452   -22.741  1.00 57.06  ? 69  GLU D C   1 
ATOM   7023  O O   . GLU D 2 69  ? -16.320 6.457   -22.025  1.00 45.52  ? 69  GLU D O   1 
ATOM   7024  C CB  . GLU D 2 69  ? -14.492 6.184   -24.198  1.00 43.97  ? 69  GLU D CB  1 
ATOM   7025  C CG  . GLU D 2 69  ? -13.168 5.835   -24.864  1.00 65.69  ? 69  GLU D CG  1 
ATOM   7026  C CD  . GLU D 2 69  ? -12.227 7.023   -24.969  1.00 73.39  ? 69  GLU D CD  1 
ATOM   7027  O OE1 . GLU D 2 69  ? -12.261 7.729   -25.999  1.00 81.64  ? 69  GLU D OE1 1 
ATOM   7028  O OE2 . GLU D 2 69  ? -11.451 7.252   -24.016  1.00 74.26  ? 69  GLU D OE2 1 
ATOM   7029  N N   . PHE D 2 70  ? -17.520 4.751   -22.862  1.00 43.83  ? 70  PHE D N   1 
ATOM   7030  C CA  . PHE D 2 70  ? -18.751 5.117   -22.173  1.00 56.79  ? 70  PHE D CA  1 
ATOM   7031  C C   . PHE D 2 70  ? -19.031 4.139   -21.038  1.00 53.60  ? 70  PHE D C   1 
ATOM   7032  O O   . PHE D 2 70  ? -18.791 2.935   -21.173  1.00 52.91  ? 70  PHE D O   1 
ATOM   7033  C CB  . PHE D 2 70  ? -19.929 5.152   -23.149  1.00 46.45  ? 70  PHE D CB  1 
ATOM   7034  C CG  . PHE D 2 70  ? -19.721 6.085   -24.304  1.00 53.02  ? 70  PHE D CG  1 
ATOM   7035  C CD1 . PHE D 2 70  ? -19.845 7.454   -24.135  1.00 44.27  ? 70  PHE D CD1 1 
ATOM   7036  C CD2 . PHE D 2 70  ? -19.393 5.595   -25.557  1.00 45.52  ? 70  PHE D CD2 1 
ATOM   7037  C CE1 . PHE D 2 70  ? -19.647 8.318   -25.193  1.00 43.87  ? 70  PHE D CE1 1 
ATOM   7038  C CE2 . PHE D 2 70  ? -19.194 6.455   -26.621  1.00 38.07  ? 70  PHE D CE2 1 
ATOM   7039  C CZ  . PHE D 2 70  ? -19.320 7.819   -26.438  1.00 43.81  ? 70  PHE D CZ  1 
ATOM   7040  N N   . ASN D 2 71  ? -19.535 4.659   -19.917  1.00 55.42  ? 71  ASN D N   1 
ATOM   7041  C CA  . ASN D 2 71  ? -19.744 3.849   -18.724  1.00 59.99  ? 71  ASN D CA  1 
ATOM   7042  C C   . ASN D 2 71  ? -21.150 3.244   -18.731  1.00 58.29  ? 71  ASN D C   1 
ATOM   7043  O O   . ASN D 2 71  ? -21.900 3.359   -19.704  1.00 50.53  ? 71  ASN D O   1 
ATOM   7044  C CB  . ASN D 2 71  ? -19.469 4.672   -17.461  1.00 56.66  ? 71  ASN D CB  1 
ATOM   7045  C CG  . ASN D 2 71  ? -20.406 5.866   -17.302  1.00 60.98  ? 71  ASN D CG  1 
ATOM   7046  O OD1 . ASN D 2 71  ? -21.588 5.807   -17.638  1.00 58.51  ? 71  ASN D OD1 1 
ATOM   7047  N ND2 . ASN D 2 71  ? -19.870 6.958   -16.770  1.00 48.64  ? 71  ASN D ND2 1 
ATOM   7048  N N   . ASN D 2 72  ? -21.525 2.602   -17.623  1.00 59.64  ? 72  ASN D N   1 
ATOM   7049  C CA  . ASN D 2 72  ? -22.760 1.828   -17.558  1.00 71.40  ? 72  ASN D CA  1 
ATOM   7050  C C   . ASN D 2 72  ? -24.013 2.685   -17.426  1.00 56.06  ? 72  ASN D C   1 
ATOM   7051  O O   . ASN D 2 72  ? -25.120 2.148   -17.539  1.00 65.83  ? 72  ASN D O   1 
ATOM   7052  C CB  . ASN D 2 72  ? -22.692 0.828   -16.399  1.00 67.28  ? 72  ASN D CB  1 
ATOM   7053  C CG  . ASN D 2 72  ? -22.108 1.432   -15.139  1.00 81.07  ? 72  ASN D CG  1 
ATOM   7054  O OD1 . ASN D 2 72  ? -21.314 2.372   -15.195  1.00 89.47  ? 72  ASN D OD1 1 
ATOM   7055  N ND2 . ASN D 2 72  ? -22.491 0.886   -13.990  1.00 84.56  ? 72  ASN D ND2 1 
ATOM   7056  N N   . LEU D 2 73  ? -23.880 3.988   -17.188  1.00 51.66  ? 73  LEU D N   1 
ATOM   7057  C CA  . LEU D 2 73  ? -25.013 4.900   -17.254  1.00 44.35  ? 73  LEU D CA  1 
ATOM   7058  C C   . LEU D 2 73  ? -25.052 5.683   -18.562  1.00 44.45  ? 73  LEU D C   1 
ATOM   7059  O O   . LEU D 2 73  ? -25.803 6.657   -18.671  1.00 47.54  ? 73  LEU D O   1 
ATOM   7060  C CB  . LEU D 2 73  ? -25.002 5.856   -16.060  1.00 47.76  ? 73  LEU D CB  1 
ATOM   7061  C CG  . LEU D 2 73  ? -25.433 5.232   -14.729  1.00 60.68  ? 73  LEU D CG  1 
ATOM   7062  C CD1 . LEU D 2 73  ? -25.517 6.284   -13.636  1.00 59.51  ? 73  LEU D CD1 1 
ATOM   7063  C CD2 . LEU D 2 73  ? -26.762 4.502   -14.880  1.00 59.82  ? 73  LEU D CD2 1 
ATOM   7064  N N   . GLU D 2 74  ? -24.254 5.286   -19.550  1.00 41.89  ? 74  GLU D N   1 
ATOM   7065  C CA  . GLU D 2 74  ? -24.266 5.870   -20.886  1.00 47.15  ? 74  GLU D CA  1 
ATOM   7066  C C   . GLU D 2 74  ? -24.427 4.774   -21.930  1.00 49.06  ? 74  GLU D C   1 
ATOM   7067  O O   . GLU D 2 74  ? -23.768 4.775   -22.974  1.00 46.30  ? 74  GLU D O   1 
ATOM   7068  C CB  . GLU D 2 74  ? -23.001 6.689   -21.139  1.00 41.91  ? 74  GLU D CB  1 
ATOM   7069  C CG  . GLU D 2 74  ? -22.730 7.763   -20.085  1.00 41.79  ? 74  GLU D CG  1 
ATOM   7070  C CD  . GLU D 2 74  ? -21.379 8.437   -20.262  1.00 56.51  ? 74  GLU D CD  1 
ATOM   7071  O OE1 . GLU D 2 74  ? -21.349 9.656   -20.542  1.00 64.31  ? 74  GLU D OE1 1 
ATOM   7072  O OE2 . GLU D 2 74  ? -20.347 7.746   -20.129  1.00 58.46  ? 74  GLU D OE2 1 
ATOM   7073  N N   . ARG D 2 75  ? -25.311 3.811   -21.651  1.00 44.49  ? 75  ARG D N   1 
ATOM   7074  C CA  . ARG D 2 75  ? -25.458 2.655   -22.529  1.00 50.45  ? 75  ARG D CA  1 
ATOM   7075  C C   . ARG D 2 75  ? -26.201 3.006   -23.814  1.00 50.66  ? 75  ARG D C   1 
ATOM   7076  O O   . ARG D 2 75  ? -26.028 2.326   -24.832  1.00 49.93  ? 75  ARG D O   1 
ATOM   7077  C CB  . ARG D 2 75  ? -26.168 1.526   -21.784  1.00 50.75  ? 75  ARG D CB  1 
ATOM   7078  C CG  . ARG D 2 75  ? -25.295 0.857   -20.736  1.00 51.63  ? 75  ARG D CG  1 
ATOM   7079  C CD  . ARG D 2 75  ? -24.433 -0.221  -21.363  1.00 71.32  ? 75  ARG D CD  1 
ATOM   7080  N NE  . ARG D 2 75  ? -25.202 -1.436  -21.602  1.00 92.87  ? 75  ARG D NE  1 
ATOM   7081  C CZ  . ARG D 2 75  ? -24.926 -2.330  -22.541  1.00 96.56  ? 75  ARG D CZ  1 
ATOM   7082  N NH1 . ARG D 2 75  ? -23.921 -2.160  -23.384  1.00 96.75  ? 75  ARG D NH1 1 
ATOM   7083  N NH2 . ARG D 2 75  ? -25.683 -3.418  -22.642  1.00 97.30  ? 75  ARG D NH2 1 
ATOM   7084  N N   . ARG D 2 76  ? -27.044 4.041   -23.786  1.00 39.66  ? 76  ARG D N   1 
ATOM   7085  C CA  . ARG D 2 76  ? -27.711 4.476   -25.009  1.00 39.58  ? 76  ARG D CA  1 
ATOM   7086  C C   . ARG D 2 76  ? -26.707 5.009   -26.025  1.00 40.79  ? 76  ARG D C   1 
ATOM   7087  O O   . ARG D 2 76  ? -26.788 4.684   -27.215  1.00 48.13  ? 76  ARG D O   1 
ATOM   7088  C CB  . ARG D 2 76  ? -28.764 5.534   -24.682  1.00 34.40  ? 76  ARG D CB  1 
ATOM   7089  C CG  . ARG D 2 76  ? -29.891 5.025   -23.796  1.00 49.40  ? 76  ARG D CG  1 
ATOM   7090  C CD  . ARG D 2 76  ? -30.707 6.185   -23.258  1.00 42.39  ? 76  ARG D CD  1 
ATOM   7091  N NE  . ARG D 2 76  ? -29.883 7.091   -22.464  1.00 47.66  ? 76  ARG D NE  1 
ATOM   7092  C CZ  . ARG D 2 76  ? -30.109 8.392   -22.339  1.00 47.84  ? 76  ARG D CZ  1 
ATOM   7093  N NH1 . ARG D 2 76  ? -31.115 8.982   -22.964  1.00 41.48  ? 76  ARG D NH1 1 
ATOM   7094  N NH2 . ARG D 2 76  ? -29.296 9.122   -21.579  1.00 40.15  ? 76  ARG D NH2 1 
ATOM   7095  N N   . ILE D 2 77  ? -25.748 5.819   -25.572  1.00 51.41  ? 77  ILE D N   1 
ATOM   7096  C CA  . ILE D 2 77  ? -24.717 6.328   -26.470  1.00 48.57  ? 77  ILE D CA  1 
ATOM   7097  C C   . ILE D 2 77  ? -23.827 5.191   -26.954  1.00 47.29  ? 77  ILE D C   1 
ATOM   7098  O O   . ILE D 2 77  ? -23.416 5.156   -28.121  1.00 54.82  ? 77  ILE D O   1 
ATOM   7099  C CB  . ILE D 2 77  ? -23.900 7.431   -25.773  1.00 45.58  ? 77  ILE D CB  1 
ATOM   7100  C CG1 . ILE D 2 77  ? -24.825 8.536   -25.263  1.00 50.00  ? 77  ILE D CG1 1 
ATOM   7101  C CG2 . ILE D 2 77  ? -22.865 8.010   -26.726  1.00 47.54  ? 77  ILE D CG2 1 
ATOM   7102  C CD1 . ILE D 2 77  ? -24.105 9.617   -24.484  1.00 49.23  ? 77  ILE D CD1 1 
ATOM   7103  N N   . GLU D 2 78  ? -23.516 4.246   -26.065  1.00 50.86  ? 78  GLU D N   1 
ATOM   7104  C CA  . GLU D 2 78  ? -22.754 3.067   -26.462  1.00 55.88  ? 78  GLU D CA  1 
ATOM   7105  C C   . GLU D 2 78  ? -23.500 2.263   -27.520  1.00 61.70  ? 78  GLU D C   1 
ATOM   7106  O O   . GLU D 2 78  ? -22.887 1.734   -28.455  1.00 58.21  ? 78  GLU D O   1 
ATOM   7107  C CB  . GLU D 2 78  ? -22.453 2.211   -25.231  1.00 51.80  ? 78  GLU D CB  1 
ATOM   7108  C CG  . GLU D 2 78  ? -21.923 0.820   -25.533  1.00 70.92  ? 78  GLU D CG  1 
ATOM   7109  C CD  . GLU D 2 78  ? -21.514 0.076   -24.275  1.00 100.29 ? 78  GLU D CD  1 
ATOM   7110  O OE1 . GLU D 2 78  ? -20.613 0.564   -23.561  1.00 104.25 ? 78  GLU D OE1 1 
ATOM   7111  O OE2 . GLU D 2 78  ? -22.101 -0.990  -23.993  1.00 94.69  ? 78  GLU D OE2 1 
ATOM   7112  N N   . ASN D 2 79  ? -24.827 2.160   -27.388  1.00 48.33  ? 79  ASN D N   1 
ATOM   7113  C CA  . ASN D 2 79  ? -25.623 1.509   -28.425  1.00 54.12  ? 79  ASN D CA  1 
ATOM   7114  C C   . ASN D 2 79  ? -25.576 2.295   -29.729  1.00 53.27  ? 79  ASN D C   1 
ATOM   7115  O O   . ASN D 2 79  ? -25.526 1.707   -30.816  1.00 53.60  ? 79  ASN D O   1 
ATOM   7116  C CB  . ASN D 2 79  ? -27.068 1.343   -27.959  1.00 47.77  ? 79  ASN D CB  1 
ATOM   7117  C CG  . ASN D 2 79  ? -27.934 0.652   -28.994  1.00 55.97  ? 79  ASN D CG  1 
ATOM   7118  O OD1 . ASN D 2 79  ? -27.576 -0.406  -29.514  1.00 47.45  ? 79  ASN D OD1 1 
ATOM   7119  N ND2 . ASN D 2 79  ? -29.074 1.255   -29.311  1.00 59.23  ? 79  ASN D ND2 1 
ATOM   7120  N N   . LEU D 2 80  ? -25.606 3.628   -29.640  1.00 48.22  ? 80  LEU D N   1 
ATOM   7121  C CA  . LEU D 2 80  ? -25.498 4.451   -30.841  1.00 49.14  ? 80  LEU D CA  1 
ATOM   7122  C C   . LEU D 2 80  ? -24.168 4.214   -31.548  1.00 50.02  ? 80  LEU D C   1 
ATOM   7123  O O   . LEU D 2 80  ? -24.117 4.127   -32.780  1.00 50.15  ? 80  LEU D O   1 
ATOM   7124  C CB  . LEU D 2 80  ? -25.670 5.927   -30.476  1.00 43.65  ? 80  LEU D CB  1 
ATOM   7125  C CG  . LEU D 2 80  ? -25.463 7.003   -31.547  1.00 57.87  ? 80  LEU D CG  1 
ATOM   7126  C CD1 . LEU D 2 80  ? -26.219 6.672   -32.822  1.00 58.27  ? 80  LEU D CD1 1 
ATOM   7127  C CD2 . LEU D 2 80  ? -25.896 8.365   -31.012  1.00 42.61  ? 80  LEU D CD2 1 
ATOM   7128  N N   . ASN D 2 81  ? -23.082 4.097   -30.782  1.00 59.18  ? 81  ASN D N   1 
ATOM   7129  C CA  . ASN D 2 81  ? -21.790 3.770   -31.377  1.00 54.62  ? 81  ASN D CA  1 
ATOM   7130  C C   . ASN D 2 81  ? -21.802 2.375   -31.991  1.00 58.44  ? 81  ASN D C   1 
ATOM   7131  O O   . ASN D 2 81  ? -21.211 2.152   -33.054  1.00 58.69  ? 81  ASN D O   1 
ATOM   7132  C CB  . ASN D 2 81  ? -20.687 3.886   -30.326  1.00 50.47  ? 81  ASN D CB  1 
ATOM   7133  C CG  . ASN D 2 81  ? -19.322 3.524   -30.875  1.00 41.54  ? 81  ASN D CG  1 
ATOM   7134  O OD1 . ASN D 2 81  ? -18.663 4.342   -31.513  1.00 54.96  ? 81  ASN D OD1 1 
ATOM   7135  N ND2 . ASN D 2 81  ? -18.889 2.294   -30.626  1.00 54.37  ? 81  ASN D ND2 1 
ATOM   7136  N N   . LYS D 2 82  ? -22.463 1.421   -31.330  1.00 50.71  ? 82  LYS D N   1 
ATOM   7137  C CA  . LYS D 2 82  ? -22.524 0.059   -31.851  1.00 54.49  ? 82  LYS D CA  1 
ATOM   7138  C C   . LYS D 2 82  ? -23.245 0.013   -33.192  1.00 56.13  ? 82  LYS D C   1 
ATOM   7139  O O   . LYS D 2 82  ? -22.775 -0.623  -34.142  1.00 55.09  ? 82  LYS D O   1 
ATOM   7140  C CB  . LYS D 2 82  ? -23.214 -0.859  -30.842  1.00 46.04  ? 82  LYS D CB  1 
ATOM   7141  C CG  . LYS D 2 82  ? -23.555 -2.229  -31.402  1.00 56.05  ? 82  LYS D CG  1 
ATOM   7142  C CD  . LYS D 2 82  ? -24.283 -3.085  -30.383  1.00 61.41  ? 82  LYS D CD  1 
ATOM   7143  C CE  . LYS D 2 82  ? -24.848 -4.339  -31.028  1.00 73.29  ? 82  LYS D CE  1 
ATOM   7144  N NZ  . LYS D 2 82  ? -23.800 -5.101  -31.762  1.00 70.69  ? 82  LYS D NZ  1 
ATOM   7145  N N   . LYS D 2 83  ? -24.395 0.685   -33.288  1.00 50.36  ? 83  LYS D N   1 
ATOM   7146  C CA  . LYS D 2 83  ? -25.107 0.742   -34.559  1.00 58.29  ? 83  LYS D CA  1 
ATOM   7147  C C   . LYS D 2 83  ? -24.272 1.421   -35.634  1.00 54.38  ? 83  LYS D C   1 
ATOM   7148  O O   . LYS D 2 83  ? -24.390 1.086   -36.818  1.00 57.59  ? 83  LYS D O   1 
ATOM   7149  C CB  . LYS D 2 83  ? -26.443 1.463   -34.378  1.00 45.76  ? 83  LYS D CB  1 
ATOM   7150  C CG  . LYS D 2 83  ? -27.579 0.558   -33.919  1.00 56.45  ? 83  LYS D CG  1 
ATOM   7151  C CD  . LYS D 2 83  ? -28.577 1.299   -33.038  1.00 55.77  ? 83  LYS D CD  1 
ATOM   7152  C CE  . LYS D 2 83  ? -28.702 2.762   -33.432  1.00 65.38  ? 83  LYS D CE  1 
ATOM   7153  N NZ  . LYS D 2 83  ? -29.782 3.453   -32.676  1.00 66.28  ? 83  LYS D NZ  1 
ATOM   7154  N N   . MET D 2 84  ? -23.419 2.369   -35.244  1.00 51.75  ? 84  MET D N   1 
ATOM   7155  C CA  . MET D 2 84  ? -22.558 3.035   -36.214  1.00 53.43  ? 84  MET D CA  1 
ATOM   7156  C C   . MET D 2 84  ? -21.471 2.094   -36.727  1.00 56.34  ? 84  MET D C   1 
ATOM   7157  O O   . MET D 2 84  ? -21.232 2.008   -37.937  1.00 54.81  ? 84  MET D O   1 
ATOM   7158  C CB  . MET D 2 84  ? -21.942 4.285   -35.587  1.00 55.84  ? 84  MET D CB  1 
ATOM   7159  C CG  . MET D 2 84  ? -21.524 5.335   -36.595  1.00 65.66  ? 84  MET D CG  1 
ATOM   7160  S SD  . MET D 2 84  ? -19.983 6.130   -36.122  1.00 66.64  ? 84  MET D SD  1 
ATOM   7161  C CE  . MET D 2 84  ? -18.840 4.763   -36.306  1.00 60.07  ? 84  MET D CE  1 
ATOM   7162  N N   . GLU D 2 85  ? -20.797 1.383   -35.817  1.00 51.96  ? 85  GLU D N   1 
ATOM   7163  C CA  . GLU D 2 85  ? -19.748 0.452   -36.227  1.00 55.28  ? 85  GLU D CA  1 
ATOM   7164  C C   . GLU D 2 85  ? -20.317 -0.696  -37.051  1.00 63.98  ? 85  GLU D C   1 
ATOM   7165  O O   . GLU D 2 85  ? -19.754 -1.069  -38.087  1.00 55.60  ? 85  GLU D O   1 
ATOM   7166  C CB  . GLU D 2 85  ? -19.016 -0.095  -35.002  1.00 53.55  ? 85  GLU D CB  1 
ATOM   7167  C CG  . GLU D 2 85  ? -18.132 0.907   -34.285  1.00 62.27  ? 85  GLU D CG  1 
ATOM   7168  C CD  . GLU D 2 85  ? -17.344 0.267   -33.160  1.00 65.63  ? 85  GLU D CD  1 
ATOM   7169  O OE1 . GLU D 2 85  ? -17.377 -0.977  -33.047  1.00 65.98  ? 85  GLU D OE1 1 
ATOM   7170  O OE2 . GLU D 2 85  ? -16.694 1.003   -32.390  1.00 66.79  ? 85  GLU D OE2 1 
ATOM   7171  N N   . ASP D 2 86  ? -21.431 -1.275  -36.598  1.00 56.30  ? 86  ASP D N   1 
ATOM   7172  C CA  . ASP D 2 86  ? -22.026 -2.394  -37.319  1.00 58.77  ? 86  ASP D CA  1 
ATOM   7173  C C   . ASP D 2 86  ? -22.587 -1.958  -38.665  1.00 53.33  ? 86  ASP D C   1 
ATOM   7174  O O   . ASP D 2 86  ? -22.566 -2.737  -39.624  1.00 65.08  ? 86  ASP D O   1 
ATOM   7175  C CB  . ASP D 2 86  ? -23.113 -3.047  -36.467  1.00 58.26  ? 86  ASP D CB  1 
ATOM   7176  C CG  . ASP D 2 86  ? -22.557 -3.680  -35.205  1.00 61.78  ? 86  ASP D CG  1 
ATOM   7177  O OD1 . ASP D 2 86  ? -21.339 -3.958  -35.167  1.00 72.22  ? 86  ASP D OD1 1 
ATOM   7178  O OD2 . ASP D 2 86  ? -23.334 -3.907  -34.253  1.00 62.36  ? 86  ASP D OD2 1 
ATOM   7179  N N   . GLY D 2 87  ? -23.091 -0.727  -38.757  1.00 49.48  ? 87  GLY D N   1 
ATOM   7180  C CA  . GLY D 2 87  ? -23.547 -0.224  -40.042  1.00 47.44  ? 87  GLY D CA  1 
ATOM   7181  C C   . GLY D 2 87  ? -22.420 -0.111  -41.051  1.00 58.61  ? 87  GLY D C   1 
ATOM   7182  O O   . GLY D 2 87  ? -22.561 -0.515  -42.207  1.00 57.93  ? 87  GLY D O   1 
ATOM   7183  N N   . PHE D 2 88  ? -21.277 0.432   -40.622  1.00 56.23  ? 88  PHE D N   1 
ATOM   7184  C CA  . PHE D 2 88  ? -20.138 0.551   -41.527  1.00 53.64  ? 88  PHE D CA  1 
ATOM   7185  C C   . PHE D 2 88  ? -19.527 -0.807  -41.844  1.00 56.28  ? 88  PHE D C   1 
ATOM   7186  O O   . PHE D 2 88  ? -19.017 -1.010  -42.951  1.00 58.84  ? 88  PHE D O   1 
ATOM   7187  C CB  . PHE D 2 88  ? -19.090 1.491   -40.933  1.00 43.92  ? 88  PHE D CB  1 
ATOM   7188  C CG  . PHE D 2 88  ? -19.432 2.944   -41.087  1.00 52.90  ? 88  PHE D CG  1 
ATOM   7189  C CD1 . PHE D 2 88  ? -19.794 3.454   -42.324  1.00 52.47  ? 88  PHE D CD1 1 
ATOM   7190  C CD2 . PHE D 2 88  ? -19.411 3.796   -39.997  1.00 43.29  ? 88  PHE D CD2 1 
ATOM   7191  C CE1 . PHE D 2 88  ? -20.117 4.788   -42.473  1.00 57.36  ? 88  PHE D CE1 1 
ATOM   7192  C CE2 . PHE D 2 88  ? -19.733 5.132   -40.138  1.00 44.37  ? 88  PHE D CE2 1 
ATOM   7193  C CZ  . PHE D 2 88  ? -20.088 5.629   -41.377  1.00 55.04  ? 88  PHE D CZ  1 
ATOM   7194  N N   . LEU D 2 89  ? -19.566 -1.743  -40.892  1.00 61.04  ? 89  LEU D N   1 
ATOM   7195  C CA  . LEU D 2 89  ? -19.121 -3.103  -41.176  1.00 62.00  ? 89  LEU D CA  1 
ATOM   7196  C C   . LEU D 2 89  ? -19.961 -3.726  -42.283  1.00 64.65  ? 89  LEU D C   1 
ATOM   7197  O O   . LEU D 2 89  ? -19.429 -4.340  -43.214  1.00 63.03  ? 89  LEU D O   1 
ATOM   7198  C CB  . LEU D 2 89  ? -19.195 -3.954  -39.907  1.00 55.96  ? 89  LEU D CB  1 
ATOM   7199  C CG  . LEU D 2 89  ? -18.881 -5.442  -40.078  1.00 62.22  ? 89  LEU D CG  1 
ATOM   7200  C CD1 . LEU D 2 89  ? -17.383 -5.661  -40.138  1.00 65.29  ? 89  LEU D CD1 1 
ATOM   7201  C CD2 . LEU D 2 89  ? -19.500 -6.273  -38.964  1.00 66.18  ? 89  LEU D CD2 1 
ATOM   7202  N N   . ASP D 2 90  ? -21.282 -3.566  -42.201  1.00 59.57  ? 90  ASP D N   1 
ATOM   7203  C CA  . ASP D 2 90  ? -22.163 -4.112  -43.226  1.00 59.51  ? 90  ASP D CA  1 
ATOM   7204  C C   . ASP D 2 90  ? -21.950 -3.421  -44.568  1.00 66.68  ? 90  ASP D C   1 
ATOM   7205  O O   . ASP D 2 90  ? -21.990 -4.072  -45.619  1.00 65.98  ? 90  ASP D O   1 
ATOM   7206  C CB  . ASP D 2 90  ? -23.620 -3.993  -42.779  1.00 59.19  ? 90  ASP D CB  1 
ATOM   7207  C CG  . ASP D 2 90  ? -23.923 -4.832  -41.551  1.00 60.21  ? 90  ASP D CG  1 
ATOM   7208  O OD1 . ASP D 2 90  ? -23.046 -5.617  -41.137  1.00 71.24  ? 90  ASP D OD1 1 
ATOM   7209  O OD2 . ASP D 2 90  ? -25.036 -4.707  -40.997  1.00 70.61  ? 90  ASP D OD2 1 
ATOM   7210  N N   . VAL D 2 91  ? -21.726 -2.105  -44.555  1.00 50.42  ? 91  VAL D N   1 
ATOM   7211  C CA  . VAL D 2 91  ? -21.552 -1.366  -45.803  1.00 60.36  ? 91  VAL D CA  1 
ATOM   7212  C C   . VAL D 2 91  ? -20.285 -1.816  -46.522  1.00 66.82  ? 91  VAL D C   1 
ATOM   7213  O O   . VAL D 2 91  ? -20.306 -2.111  -47.723  1.00 67.43  ? 91  VAL D O   1 
ATOM   7214  C CB  . VAL D 2 91  ? -21.535 0.149   -45.533  1.00 49.34  ? 91  VAL D CB  1 
ATOM   7215  C CG1 . VAL D 2 91  ? -21.058 0.900   -46.768  1.00 44.92  ? 91  VAL D CG1 1 
ATOM   7216  C CG2 . VAL D 2 91  ? -22.914 0.627   -45.122  1.00 43.79  ? 91  VAL D CG2 1 
ATOM   7217  N N   . TRP D 2 92  ? -19.164 -1.876  -45.801  1.00 65.08  ? 92  TRP D N   1 
ATOM   7218  C CA  . TRP D 2 92  ? -17.904 -2.250  -46.436  1.00 59.25  ? 92  TRP D CA  1 
ATOM   7219  C C   . TRP D 2 92  ? -17.896 -3.719  -46.841  1.00 67.11  ? 92  TRP D C   1 
ATOM   7220  O O   . TRP D 2 92  ? -17.354 -4.071  -47.895  1.00 73.68  ? 92  TRP D O   1 
ATOM   7221  C CB  . TRP D 2 92  ? -16.729 -1.942  -45.508  1.00 53.71  ? 92  TRP D CB  1 
ATOM   7222  C CG  . TRP D 2 92  ? -16.433 -0.480  -45.372  1.00 52.70  ? 92  TRP D CG  1 
ATOM   7223  C CD1 . TRP D 2 92  ? -16.509 0.271   -44.235  1.00 52.87  ? 92  TRP D CD1 1 
ATOM   7224  C CD2 . TRP D 2 92  ? -16.021 0.413   -46.415  1.00 58.94  ? 92  TRP D CD2 1 
ATOM   7225  N NE1 . TRP D 2 92  ? -16.163 1.573   -44.503  1.00 58.30  ? 92  TRP D NE1 1 
ATOM   7226  C CE2 . TRP D 2 92  ? -15.860 1.687   -45.834  1.00 56.38  ? 92  TRP D CE2 1 
ATOM   7227  C CE3 . TRP D 2 92  ? -15.768 0.258   -47.781  1.00 57.70  ? 92  TRP D CE3 1 
ATOM   7228  C CZ2 . TRP D 2 92  ? -15.456 2.798   -46.572  1.00 59.53  ? 92  TRP D CZ2 1 
ATOM   7229  C CZ3 . TRP D 2 92  ? -15.371 1.363   -48.513  1.00 56.91  ? 92  TRP D CZ3 1 
ATOM   7230  C CH2 . TRP D 2 92  ? -15.222 2.616   -47.908  1.00 58.91  ? 92  TRP D CH2 1 
ATOM   7231  N N   . THR D 2 93  ? -18.485 -4.591  -46.018  1.00 57.89  ? 93  THR D N   1 
ATOM   7232  C CA  . THR D 2 93  ? -18.502 -6.015  -46.340  1.00 58.96  ? 93  THR D CA  1 
ATOM   7233  C C   . THR D 2 93  ? -19.260 -6.277  -47.636  1.00 76.28  ? 93  THR D C   1 
ATOM   7234  O O   . THR D 2 93  ? -18.773 -6.989  -48.522  1.00 75.44  ? 93  THR D O   1 
ATOM   7235  C CB  . THR D 2 93  ? -19.119 -6.808  -45.187  1.00 57.26  ? 93  THR D CB  1 
ATOM   7236  O OG1 . THR D 2 93  ? -18.281 -6.703  -44.028  1.00 62.31  ? 93  THR D OG1 1 
ATOM   7237  C CG2 . THR D 2 93  ? -19.271 -8.274  -45.566  1.00 62.21  ? 93  THR D CG2 1 
ATOM   7238  N N   . TYR D 2 94  ? -20.456 -5.698  -47.766  1.00 67.90  ? 94  TYR D N   1 
ATOM   7239  C CA  . TYR D 2 94  ? -21.255 -5.898  -48.971  1.00 67.25  ? 94  TYR D CA  1 
ATOM   7240  C C   . TYR D 2 94  ? -20.559 -5.322  -50.197  1.00 67.46  ? 94  TYR D C   1 
ATOM   7241  O O   . TYR D 2 94  ? -20.522 -5.959  -51.256  1.00 71.60  ? 94  TYR D O   1 
ATOM   7242  C CB  . TYR D 2 94  ? -22.633 -5.265  -48.783  1.00 65.88  ? 94  TYR D CB  1 
ATOM   7243  C CG  . TYR D 2 94  ? -23.658 -5.645  -49.828  1.00 66.51  ? 94  TYR D CG  1 
ATOM   7244  C CD1 . TYR D 2 94  ? -24.076 -6.961  -49.973  1.00 69.12  ? 94  TYR D CD1 1 
ATOM   7245  C CD2 . TYR D 2 94  ? -24.232 -4.681  -50.648  1.00 75.49  ? 94  TYR D CD2 1 
ATOM   7246  C CE1 . TYR D 2 94  ? -25.022 -7.310  -50.919  1.00 70.50  ? 94  TYR D CE1 1 
ATOM   7247  C CE2 . TYR D 2 94  ? -25.180 -5.019  -51.595  1.00 62.46  ? 94  TYR D CE2 1 
ATOM   7248  C CZ  . TYR D 2 94  ? -25.573 -6.335  -51.724  1.00 67.27  ? 94  TYR D CZ  1 
ATOM   7249  O OH  . TYR D 2 94  ? -26.515 -6.679  -52.668  1.00 75.91  ? 94  TYR D OH  1 
ATOM   7250  N N   . ASN D 2 95  ? -19.996 -4.120  -50.070  1.00 63.18  ? 95  ASN D N   1 
ATOM   7251  C CA  . ASN D 2 95  ? -19.305 -3.502  -51.197  1.00 67.92  ? 95  ASN D CA  1 
ATOM   7252  C C   . ASN D 2 95  ? -18.044 -4.273  -51.569  1.00 65.39  ? 95  ASN D C   1 
ATOM   7253  O O   . ASN D 2 95  ? -17.746 -4.441  -52.756  1.00 73.68  ? 95  ASN D O   1 
ATOM   7254  C CB  . ASN D 2 95  ? -18.980 -2.046  -50.873  1.00 59.54  ? 95  ASN D CB  1 
ATOM   7255  C CG  . ASN D 2 95  ? -20.212 -1.166  -50.879  1.00 76.34  ? 95  ASN D CG  1 
ATOM   7256  O OD1 . ASN D 2 95  ? -21.332 -1.654  -51.028  1.00 80.51  ? 95  ASN D OD1 1 
ATOM   7257  N ND2 . ASN D 2 95  ? -20.014 0.136   -50.713  1.00 82.71  ? 95  ASN D ND2 1 
ATOM   7258  N N   . ALA D 2 96  ? -17.289 -4.744  -50.574  1.00 69.50  ? 96  ALA D N   1 
ATOM   7259  C CA  . ALA D 2 96  ? -16.081 -5.509  -50.871  1.00 70.22  ? 96  ALA D CA  1 
ATOM   7260  C C   . ALA D 2 96  ? -16.411 -6.834  -51.549  1.00 68.90  ? 96  ALA D C   1 
ATOM   7261  O O   . ALA D 2 96  ? -15.754 -7.219  -52.522  1.00 61.39  ? 96  ALA D O   1 
ATOM   7262  C CB  . ALA D 2 96  ? -15.278 -5.749  -49.593  1.00 63.57  ? 96  ALA D CB  1 
ATOM   7263  N N   . GLU D 2 97  ? -17.423 -7.546  -51.048  1.00 74.86  ? 97  GLU D N   1 
ATOM   7264  C CA  . GLU D 2 97  ? -17.756 -8.855  -51.602  1.00 65.48  ? 97  GLU D CA  1 
ATOM   7265  C C   . GLU D 2 97  ? -18.298 -8.736  -53.022  1.00 76.17  ? 97  GLU D C   1 
ATOM   7266  O O   . GLU D 2 97  ? -17.894 -9.490  -53.915  1.00 77.58  ? 97  GLU D O   1 
ATOM   7267  C CB  . GLU D 2 97  ? -18.764 -9.566  -50.697  1.00 56.80  ? 97  GLU D CB  1 
ATOM   7268  C CG  . GLU D 2 97  ? -18.185 -10.053 -49.377  1.00 61.83  ? 97  GLU D CG  1 
ATOM   7269  C CD  . GLU D 2 97  ? -17.333 -11.298 -49.532  1.00 76.27  ? 97  GLU D CD  1 
ATOM   7270  O OE1 . GLU D 2 97  ? -17.453 -11.980 -50.573  1.00 84.15  ? 97  GLU D OE1 1 
ATOM   7271  O OE2 . GLU D 2 97  ? -16.542 -11.596 -48.612  1.00 68.28  ? 97  GLU D OE2 1 
ATOM   7272  N N   . LEU D 2 98  ? -19.216 -7.794  -53.252  1.00 70.23  ? 98  LEU D N   1 
ATOM   7273  C CA  . LEU D 2 98  ? -19.797 -7.651  -54.583  1.00 68.23  ? 98  LEU D CA  1 
ATOM   7274  C C   . LEU D 2 98  ? -18.779 -7.114  -55.580  1.00 76.05  ? 98  LEU D C   1 
ATOM   7275  O O   . LEU D 2 98  ? -18.793 -7.501  -56.754  1.00 78.29  ? 98  LEU D O   1 
ATOM   7276  C CB  . LEU D 2 98  ? -21.026 -6.746  -54.535  1.00 66.20  ? 98  LEU D CB  1 
ATOM   7277  C CG  . LEU D 2 98  ? -22.265 -7.282  -53.815  1.00 72.18  ? 98  LEU D CG  1 
ATOM   7278  C CD1 . LEU D 2 98  ? -23.511 -6.615  -54.370  1.00 67.78  ? 98  LEU D CD1 1 
ATOM   7279  C CD2 . LEU D 2 98  ? -22.365 -8.796  -53.925  1.00 63.38  ? 98  LEU D CD2 1 
ATOM   7280  N N   . LEU D 2 99  ? -17.894 -6.218  -55.137  1.00 71.45  ? 99  LEU D N   1 
ATOM   7281  C CA  . LEU D 2 99  ? -16.881 -5.679  -56.040  1.00 78.05  ? 99  LEU D CA  1 
ATOM   7282  C C   . LEU D 2 99  ? -15.928 -6.770  -56.508  1.00 80.10  ? 99  LEU D C   1 
ATOM   7283  O O   . LEU D 2 99  ? -15.486 -6.768  -57.663  1.00 78.59  ? 99  LEU D O   1 
ATOM   7284  C CB  . LEU D 2 99  ? -16.108 -4.555  -55.357  1.00 63.37  ? 99  LEU D CB  1 
ATOM   7285  C CG  . LEU D 2 99  ? -15.434 -3.561  -56.301  1.00 76.42  ? 99  LEU D CG  1 
ATOM   7286  C CD1 . LEU D 2 99  ? -16.403 -2.451  -56.690  1.00 82.04  ? 99  LEU D CD1 1 
ATOM   7287  C CD2 . LEU D 2 99  ? -14.175 -2.999  -55.667  1.00 83.23  ? 99  LEU D CD2 1 
ATOM   7288  N N   . VAL D 2 100 ? -15.584 -7.703  -55.617  1.00 75.26  ? 100 VAL D N   1 
ATOM   7289  C CA  . VAL D 2 100 ? -14.782 -8.856  -56.018  1.00 81.29  ? 100 VAL D CA  1 
ATOM   7290  C C   . VAL D 2 100 ? -15.557 -9.721  -57.006  1.00 83.65  ? 100 VAL D C   1 
ATOM   7291  O O   . VAL D 2 100 ? -15.022 -10.149 -58.036  1.00 81.19  ? 100 VAL D O   1 
ATOM   7292  C CB  . VAL D 2 100 ? -14.342 -9.657  -54.778  1.00 68.54  ? 100 VAL D CB  1 
ATOM   7293  C CG1 . VAL D 2 100 ? -14.097 -11.118 -55.135  1.00 78.37  ? 100 VAL D CG1 1 
ATOM   7294  C CG2 . VAL D 2 100 ? -13.090 -9.040  -54.171  1.00 74.62  ? 100 VAL D CG2 1 
ATOM   7295  N N   . LEU D 2 101 ? -16.834 -9.983  -56.712  1.00 77.02  ? 101 LEU D N   1 
ATOM   7296  C CA  . LEU D 2 101 ? -17.649 -10.799 -57.608  1.00 70.51  ? 101 LEU D CA  1 
ATOM   7297  C C   . LEU D 2 101 ? -17.847 -10.118 -58.957  1.00 78.65  ? 101 LEU D C   1 
ATOM   7298  O O   . LEU D 2 101 ? -17.742 -10.762 -60.007  1.00 84.10  ? 101 LEU D O   1 
ATOM   7299  C CB  . LEU D 2 101 ? -19.003 -11.099 -56.964  1.00 63.57  ? 101 LEU D CB  1 
ATOM   7300  C CG  . LEU D 2 101 ? -19.066 -12.090 -55.800  1.00 75.38  ? 101 LEU D CG  1 
ATOM   7301  C CD1 . LEU D 2 101 ? -20.484 -12.173 -55.257  1.00 74.67  ? 101 LEU D CD1 1 
ATOM   7302  C CD2 . LEU D 2 101 ? -18.585 -13.463 -56.226  1.00 81.40  ? 101 LEU D CD2 1 
ATOM   7303  N N   . MET D 2 102 ? -18.133 -8.814  -58.948  1.00 76.37  ? 102 MET D N   1 
ATOM   7304  C CA  . MET D 2 102 ? -18.428 -8.111  -60.193  1.00 72.71  ? 102 MET D CA  1 
ATOM   7305  C C   . MET D 2 102 ? -17.193 -7.983  -61.076  1.00 86.73  ? 102 MET D C   1 
ATOM   7306  O O   . MET D 2 102 ? -17.272 -8.189  -62.293  1.00 78.17  ? 102 MET D O   1 
ATOM   7307  C CB  . MET D 2 102 ? -19.011 -6.731  -59.889  1.00 77.95  ? 102 MET D CB  1 
ATOM   7308  C CG  . MET D 2 102 ? -20.531 -6.690  -59.855  1.00 91.24  ? 102 MET D CG  1 
ATOM   7309  S SD  . MET D 2 102 ? -21.174 -5.534  -58.629  1.00 91.95  ? 102 MET D SD  1 
ATOM   7310  C CE  . MET D 2 102 ? -20.080 -4.136  -58.867  1.00 69.24  ? 102 MET D CE  1 
ATOM   7311  N N   . GLU D 2 103 ? -16.048 -7.642  -60.493  1.00 78.89  ? 103 GLU D N   1 
ATOM   7312  C CA  . GLU D 2 103 ? -14.863 -7.369  -61.291  1.00 73.49  ? 103 GLU D CA  1 
ATOM   7313  C C   . GLU D 2 103 ? -14.055 -8.615  -61.629  1.00 82.29  ? 103 GLU D C   1 
ATOM   7314  O O   . GLU D 2 103 ? -13.161 -8.541  -62.479  1.00 81.77  ? 103 GLU D O   1 
ATOM   7315  C CB  . GLU D 2 103 ? -13.984 -6.343  -60.572  1.00 71.64  ? 103 GLU D CB  1 
ATOM   7316  C CG  . GLU D 2 103 ? -13.422 -5.257  -61.490  1.00 91.22  ? 103 GLU D CG  1 
ATOM   7317  C CD  . GLU D 2 103 ? -14.492 -4.373  -62.142  1.00 99.96  ? 103 GLU D CD  1 
ATOM   7318  O OE1 . GLU D 2 103 ? -14.098 -3.475  -62.923  1.00 102.71 ? 103 GLU D OE1 1 
ATOM   7319  O OE2 . GLU D 2 103 ? -15.702 -4.550  -61.888  1.00 108.65 ? 103 GLU D OE2 1 
ATOM   7320  N N   . ASN D 2 104 ? -14.339 -9.753  -60.994  1.00 79.50  ? 104 ASN D N   1 
ATOM   7321  C CA  . ASN D 2 104 ? -13.756 -11.004 -61.463  1.00 82.02  ? 104 ASN D CA  1 
ATOM   7322  C C   . ASN D 2 104 ? -14.373 -11.426 -62.790  1.00 89.01  ? 104 ASN D C   1 
ATOM   7323  O O   . ASN D 2 104 ? -13.683 -11.977 -63.655  1.00 88.05  ? 104 ASN D O   1 
ATOM   7324  C CB  . ASN D 2 104 ? -13.923 -12.100 -60.412  1.00 72.76  ? 104 ASN D CB  1 
ATOM   7325  C CG  . ASN D 2 104 ? -12.883 -12.013 -59.311  1.00 75.08  ? 104 ASN D CG  1 
ATOM   7326  O OD1 . ASN D 2 104 ? -11.920 -11.252 -59.412  1.00 76.08  ? 104 ASN D OD1 1 
ATOM   7327  N ND2 . ASN D 2 104 ? -13.066 -12.802 -58.259  1.00 73.11  ? 104 ASN D ND2 1 
ATOM   7328  N N   . GLU D 2 105 ? -15.674 -11.180 -62.969  1.00 84.53  ? 105 GLU D N   1 
ATOM   7329  C CA  . GLU D 2 105 ? -16.301 -11.461 -64.257  1.00 94.64  ? 105 GLU D CA  1 
ATOM   7330  C C   . GLU D 2 105 ? -15.794 -10.514 -65.335  1.00 92.46  ? 105 GLU D C   1 
ATOM   7331  O O   . GLU D 2 105 ? -15.525 -10.939 -66.464  1.00 102.53 ? 105 GLU D O   1 
ATOM   7332  C CB  . GLU D 2 105 ? -17.819 -11.372 -64.139  1.00 92.79  ? 105 GLU D CB  1 
ATOM   7333  C CG  . GLU D 2 105 ? -18.521 -12.643 -64.563  1.00 101.65 ? 105 GLU D CG  1 
ATOM   7334  C CD  . GLU D 2 105 ? -20.010 -12.588 -64.327  1.00 106.97 ? 105 GLU D CD  1 
ATOM   7335  O OE1 . GLU D 2 105 ? -20.647 -11.596 -64.737  1.00 105.41 ? 105 GLU D OE1 1 
ATOM   7336  O OE2 . GLU D 2 105 ? -20.542 -13.534 -63.714  1.00 110.68 ? 105 GLU D OE2 1 
ATOM   7337  N N   . ARG D 2 106 ? -15.662 -9.226  -65.009  1.00 79.38  ? 106 ARG D N   1 
ATOM   7338  C CA  . ARG D 2 106 ? -15.087 -8.287  -65.965  1.00 88.62  ? 106 ARG D CA  1 
ATOM   7339  C C   . ARG D 2 106 ? -13.635 -8.632  -66.273  1.00 94.05  ? 106 ARG D C   1 
ATOM   7340  O O   . ARG D 2 106 ? -13.159 -8.383  -67.387  1.00 93.86  ? 106 ARG D O   1 
ATOM   7341  C CB  . ARG D 2 106 ? -15.218 -6.856  -65.437  1.00 84.98  ? 106 ARG D CB  1 
ATOM   7342  C CG  . ARG D 2 106 ? -14.502 -5.813  -66.282  1.00 103.64 ? 106 ARG D CG  1 
ATOM   7343  C CD  . ARG D 2 106 ? -15.157 -4.439  -66.205  1.00 115.39 ? 106 ARG D CD  1 
ATOM   7344  N NE  . ARG D 2 106 ? -16.083 -4.205  -67.309  1.00 120.75 ? 106 ARG D NE  1 
ATOM   7345  C CZ  . ARG D 2 106 ? -15.713 -3.989  -68.565  1.00 125.17 ? 106 ARG D CZ  1 
ATOM   7346  N NH1 . ARG D 2 106 ? -14.439 -4.010  -68.925  1.00 120.47 ? 106 ARG D NH1 1 
ATOM   7347  N NH2 . ARG D 2 106 ? -16.644 -3.756  -69.486  1.00 117.23 ? 106 ARG D NH2 1 
ATOM   7348  N N   . THR D 2 107 ? -12.921 -9.218  -65.309  1.00 97.79  ? 107 THR D N   1 
ATOM   7349  C CA  . THR D 2 107 ? -11.558 -9.677  -65.565  1.00 94.45  ? 107 THR D CA  1 
ATOM   7350  C C   . THR D 2 107 ? -11.544 -10.864 -66.521  1.00 98.31  ? 107 THR D C   1 
ATOM   7351  O O   . THR D 2 107 ? -10.781 -10.882 -67.494  1.00 95.01  ? 107 THR D O   1 
ATOM   7352  C CB  . THR D 2 107 ? -10.868 -10.040 -64.247  1.00 79.42  ? 107 THR D CB  1 
ATOM   7353  O OG1 . THR D 2 107 ? -10.396 -8.848  -63.608  1.00 91.29  ? 107 THR D OG1 1 
ATOM   7354  C CG2 . THR D 2 107 ? -9.697  -10.985 -64.491  1.00 82.39  ? 107 THR D CG2 1 
ATOM   7355  N N   . LEU D 2 108 ? -12.383 -11.870 -66.263  1.00 91.83  ? 108 LEU D N   1 
ATOM   7356  C CA  . LEU D 2 108 ? -12.373 -13.059 -67.108  1.00 90.95  ? 108 LEU D CA  1 
ATOM   7357  C C   . LEU D 2 108 ? -12.932 -12.769 -68.495  1.00 104.02 ? 108 LEU D C   1 
ATOM   7358  O O   . LEU D 2 108 ? -12.470 -13.357 -69.480  1.00 107.50 ? 108 LEU D O   1 
ATOM   7359  C CB  . LEU D 2 108 ? -13.144 -14.195 -66.437  1.00 74.93  ? 108 LEU D CB  1 
ATOM   7360  C CG  . LEU D 2 108 ? -12.548 -14.700 -65.118  1.00 89.15  ? 108 LEU D CG  1 
ATOM   7361  C CD1 . LEU D 2 108 ? -13.096 -16.075 -64.761  1.00 74.96  ? 108 LEU D CD1 1 
ATOM   7362  C CD2 . LEU D 2 108 ? -11.025 -14.722 -65.170  1.00 93.58  ? 108 LEU D CD2 1 
ATOM   7363  N N   . ASP D 2 109 ? -13.915 -11.872 -68.599  1.00 98.09  ? 109 ASP D N   1 
ATOM   7364  C CA  . ASP D 2 109 ? -14.371 -11.434 -69.913  1.00 103.03 ? 109 ASP D CA  1 
ATOM   7365  C C   . ASP D 2 109 ? -13.374 -10.503 -70.590  1.00 105.46 ? 109 ASP D C   1 
ATOM   7366  O O   . ASP D 2 109 ? -13.545 -10.194 -71.774  1.00 113.88 ? 109 ASP D O   1 
ATOM   7367  C CB  . ASP D 2 109 ? -15.736 -10.748 -69.807  1.00 107.02 ? 109 ASP D CB  1 
ATOM   7368  C CG  . ASP D 2 109 ? -16.767 -11.608 -69.100  1.00 118.74 ? 109 ASP D CG  1 
ATOM   7369  O OD1 . ASP D 2 109 ? -17.906 -11.134 -68.905  1.00 119.97 ? 109 ASP D OD1 1 
ATOM   7370  O OD2 . ASP D 2 109 ? -16.430 -12.749 -68.716  1.00 117.52 ? 109 ASP D OD2 1 
ATOM   7371  N N   . PHE D 2 110 ? -12.353 -10.040 -69.866  1.00 108.93 ? 110 PHE D N   1 
ATOM   7372  C CA  . PHE D 2 110 ? -11.257 -9.303  -70.485  1.00 110.20 ? 110 PHE D CA  1 
ATOM   7373  C C   . PHE D 2 110 ? -10.266 -10.259 -71.137  1.00 110.36 ? 110 PHE D C   1 
ATOM   7374  O O   . PHE D 2 110 ? -9.846  -10.050 -72.280  1.00 113.41 ? 110 PHE D O   1 
ATOM   7375  C CB  . PHE D 2 110 ? -10.567 -8.424  -69.439  1.00 95.17  ? 110 PHE D CB  1 
ATOM   7376  C CG  . PHE D 2 110 ? -9.471  -7.557  -69.989  1.00 99.51  ? 110 PHE D CG  1 
ATOM   7377  C CD1 . PHE D 2 110 ? -9.767  -6.472  -70.796  1.00 102.37 ? 110 PHE D CD1 1 
ATOM   7378  C CD2 . PHE D 2 110 ? -8.146  -7.811  -69.677  1.00 97.25  ? 110 PHE D CD2 1 
ATOM   7379  C CE1 . PHE D 2 110 ? -8.762  -5.666  -71.297  1.00 96.61  ? 110 PHE D CE1 1 
ATOM   7380  C CE2 . PHE D 2 110 ? -7.136  -7.007  -70.172  1.00 96.66  ? 110 PHE D CE2 1 
ATOM   7381  C CZ  . PHE D 2 110 ? -7.445  -5.933  -70.984  1.00 96.83  ? 110 PHE D CZ  1 
ATOM   7382  N N   . HIS D 2 111 ? -9.887  -11.322 -70.420  1.00 108.59 ? 111 HIS D N   1 
ATOM   7383  C CA  . HIS D 2 111 ? -9.083  -12.378 -71.027  1.00 112.08 ? 111 HIS D CA  1 
ATOM   7384  C C   . HIS D 2 111 ? -9.859  -13.087 -72.127  1.00 117.82 ? 111 HIS D C   1 
ATOM   7385  O O   . HIS D 2 111 ? -9.290  -13.460 -73.160  1.00 114.27 ? 111 HIS D O   1 
ATOM   7386  C CB  . HIS D 2 111 ? -8.634  -13.376 -69.960  1.00 103.90 ? 111 HIS D CB  1 
ATOM   7387  C CG  . HIS D 2 111 ? -7.825  -12.762 -68.860  1.00 108.04 ? 111 HIS D CG  1 
ATOM   7388  N ND1 . HIS D 2 111 ? -7.114  -11.592 -69.023  1.00 105.32 ? 111 HIS D ND1 1 
ATOM   7389  C CD2 . HIS D 2 111 ? -7.620  -13.151 -67.580  1.00 103.94 ? 111 HIS D CD2 1 
ATOM   7390  C CE1 . HIS D 2 111 ? -6.502  -11.291 -67.892  1.00 106.53 ? 111 HIS D CE1 1 
ATOM   7391  N NE2 . HIS D 2 111 ? -6.792  -12.222 -67.001  1.00 105.15 ? 111 HIS D NE2 1 
ATOM   7392  N N   . ASP D 2 112 ? -11.162 -13.291 -71.918  1.00 119.46 ? 112 ASP D N   1 
ATOM   7393  C CA  . ASP D 2 112 ? -11.993 -13.906 -72.947  1.00 122.01 ? 112 ASP D CA  1 
ATOM   7394  C C   . ASP D 2 112 ? -12.040 -13.044 -74.201  1.00 121.19 ? 112 ASP D C   1 
ATOM   7395  O O   . ASP D 2 112 ? -11.999 -13.562 -75.322  1.00 123.08 ? 112 ASP D O   1 
ATOM   7396  C CB  . ASP D 2 112 ? -13.402 -14.148 -72.406  1.00 129.25 ? 112 ASP D CB  1 
ATOM   7397  C CG  . ASP D 2 112 ? -14.187 -15.137 -73.243  1.00 148.95 ? 112 ASP D CG  1 
ATOM   7398  O OD1 . ASP D 2 112 ? -13.961 -16.356 -73.091  1.00 153.97 ? 112 ASP D OD1 1 
ATOM   7399  O OD2 . ASP D 2 112 ? -15.030 -14.696 -74.051  1.00 156.95 ? 112 ASP D OD2 1 
ATOM   7400  N N   . SER D 2 113 ? -12.132 -11.725 -74.034  1.00 120.24 ? 113 SER D N   1 
ATOM   7401  C CA  . SER D 2 113 ? -12.126 -10.839 -75.193  1.00 118.91 ? 113 SER D CA  1 
ATOM   7402  C C   . SER D 2 113 ? -10.785 -10.883 -75.915  1.00 118.13 ? 113 SER D C   1 
ATOM   7403  O O   . SER D 2 113 ? -10.734 -11.108 -77.129  1.00 126.78 ? 113 SER D O   1 
ATOM   7404  C CB  . SER D 2 113 ? -12.457 -9.411  -74.762  1.00 121.25 ? 113 SER D CB  1 
ATOM   7405  O OG  . SER D 2 113 ? -12.299 -8.505  -75.839  1.00 114.68 ? 113 SER D OG  1 
ATOM   7406  N N   . ASN D 2 114 ? -9.686  -10.707 -75.174  1.00 119.61 ? 114 ASN D N   1 
ATOM   7407  C CA  . ASN D 2 114 ? -8.379  -10.526 -75.803  1.00 118.19 ? 114 ASN D CA  1 
ATOM   7408  C C   . ASN D 2 114 ? -7.983  -11.734 -76.643  1.00 115.07 ? 114 ASN D C   1 
ATOM   7409  O O   . ASN D 2 114 ? -7.382  -11.582 -77.713  1.00 116.00 ? 114 ASN D O   1 
ATOM   7410  C CB  . ASN D 2 114 ? -7.318  -10.248 -74.739  1.00 114.29 ? 114 ASN D CB  1 
ATOM   7411  C CG  . ASN D 2 114 ? -7.580  -8.967  -73.974  1.00 112.41 ? 114 ASN D CG  1 
ATOM   7412  O OD1 . ASN D 2 114 ? -8.306  -8.089  -74.441  1.00 112.37 ? 114 ASN D OD1 1 
ATOM   7413  N ND2 . ASN D 2 114 ? -6.987  -8.853  -72.792  1.00 107.31 ? 114 ASN D ND2 1 
ATOM   7414  N N   . VAL D 2 115 ? -8.301  -12.942 -76.172  1.00 114.65 ? 115 VAL D N   1 
ATOM   7415  C CA  . VAL D 2 115 ? -7.987  -14.143 -76.943  1.00 112.08 ? 115 VAL D CA  1 
ATOM   7416  C C   . VAL D 2 115 ? -8.734  -14.133 -78.271  1.00 119.79 ? 115 VAL D C   1 
ATOM   7417  O O   . VAL D 2 115 ? -8.171  -14.472 -79.319  1.00 126.74 ? 115 VAL D O   1 
ATOM   7418  C CB  . VAL D 2 115 ? -8.301  -15.405 -76.118  1.00 114.06 ? 115 VAL D CB  1 
ATOM   7419  C CG1 . VAL D 2 115 ? -8.136  -16.653 -76.970  1.00 128.90 ? 115 VAL D CG1 1 
ATOM   7420  C CG2 . VAL D 2 115 ? -7.400  -15.473 -74.896  1.00 114.52 ? 115 VAL D CG2 1 
ATOM   7421  N N   . LYS D 2 116 ? -10.011 -13.742 -78.251  1.00 124.10 ? 116 LYS D N   1 
ATOM   7422  C CA  . LYS D 2 116 ? -10.770 -13.648 -79.493  1.00 123.33 ? 116 LYS D CA  1 
ATOM   7423  C C   . LYS D 2 116 ? -10.247 -12.533 -80.391  1.00 123.46 ? 116 LYS D C   1 
ATOM   7424  O O   . LYS D 2 116 ? -10.318 -12.647 -81.620  1.00 137.82 ? 116 LYS D O   1 
ATOM   7425  C CB  . LYS D 2 116 ? -12.255 -13.434 -79.195  1.00 124.72 ? 116 LYS D CB  1 
ATOM   7426  C CG  . LYS D 2 116 ? -13.155 -13.636 -80.405  1.00 136.49 ? 116 LYS D CG  1 
ATOM   7427  C CD  . LYS D 2 116 ? -14.593 -13.245 -80.110  1.00 138.50 ? 116 LYS D CD  1 
ATOM   7428  C CE  . LYS D 2 116 ? -14.731 -11.743 -79.921  1.00 134.33 ? 116 LYS D CE  1 
ATOM   7429  N NZ  . LYS D 2 116 ? -16.150 -11.340 -79.721  1.00 133.86 ? 116 LYS D NZ  1 
ATOM   7430  N N   . ASN D 2 117 ? -9.732  -11.449 -79.803  1.00 122.30 ? 117 ASN D N   1 
ATOM   7431  C CA  . ASN D 2 117 ? -9.162  -10.371 -80.607  1.00 123.57 ? 117 ASN D CA  1 
ATOM   7432  C C   . ASN D 2 117 ? -7.954  -10.856 -81.397  1.00 130.68 ? 117 ASN D C   1 
ATOM   7433  O O   . ASN D 2 117 ? -7.774  -10.484 -82.563  1.00 134.55 ? 117 ASN D O   1 
ATOM   7434  C CB  . ASN D 2 117 ? -8.769  -9.194  -79.714  1.00 126.00 ? 117 ASN D CB  1 
ATOM   7435  C CG  . ASN D 2 117 ? -9.878  -8.779  -78.771  1.00 133.78 ? 117 ASN D CG  1 
ATOM   7436  O OD1 . ASN D 2 117 ? -11.046 -9.104  -78.985  1.00 134.14 ? 117 ASN D OD1 1 
ATOM   7437  N ND2 . ASN D 2 117 ? -9.517  -8.055  -77.718  1.00 131.20 ? 117 ASN D ND2 1 
ATOM   7438  N N   . LEU D 2 118 ? -7.108  -11.679 -80.772  1.00 124.48 ? 118 LEU D N   1 
ATOM   7439  C CA  . LEU D 2 118 ? -5.933  -12.202 -81.460  1.00 127.26 ? 118 LEU D CA  1 
ATOM   7440  C C   . LEU D 2 118 ? -6.331  -13.105 -82.620  1.00 138.13 ? 118 LEU D C   1 
ATOM   7441  O O   . LEU D 2 118 ? -5.698  -13.079 -83.682  1.00 144.31 ? 118 LEU D O   1 
ATOM   7442  C CB  . LEU D 2 118 ? -5.043  -12.952 -80.469  1.00 118.53 ? 118 LEU D CB  1 
ATOM   7443  C CG  . LEU D 2 118 ? -3.534  -12.809 -80.666  1.00 119.12 ? 118 LEU D CG  1 
ATOM   7444  C CD1 . LEU D 2 118 ? -3.132  -11.343 -80.632  1.00 117.58 ? 118 LEU D CD1 1 
ATOM   7445  C CD2 . LEU D 2 118 ? -2.783  -13.596 -79.605  1.00 116.90 ? 118 LEU D CD2 1 
ATOM   7446  N N   . TYR D 2 119 ? -7.376  -13.917 -82.434  1.00 136.73 ? 119 TYR D N   1 
ATOM   7447  C CA  . TYR D 2 119 ? -7.869  -14.755 -83.523  1.00 136.90 ? 119 TYR D CA  1 
ATOM   7448  C C   . TYR D 2 119 ? -8.386  -13.908 -84.680  1.00 142.00 ? 119 TYR D C   1 
ATOM   7449  O O   . TYR D 2 119 ? -8.147  -14.231 -85.850  1.00 156.57 ? 119 TYR D O   1 
ATOM   7450  C CB  . TYR D 2 119 ? -8.964  -15.691 -83.008  1.00 141.74 ? 119 TYR D CB  1 
ATOM   7451  C CG  . TYR D 2 119 ? -9.651  -16.503 -84.084  1.00 149.99 ? 119 TYR D CG  1 
ATOM   7452  C CD1 . TYR D 2 119 ? -9.114  -17.705 -84.525  1.00 155.13 ? 119 TYR D CD1 1 
ATOM   7453  C CD2 . TYR D 2 119 ? -10.845 -16.072 -84.653  1.00 148.99 ? 119 TYR D CD2 1 
ATOM   7454  C CE1 . TYR D 2 119 ? -9.741  -18.451 -85.507  1.00 159.15 ? 119 TYR D CE1 1 
ATOM   7455  C CE2 . TYR D 2 119 ? -11.477 -16.811 -85.635  1.00 155.13 ? 119 TYR D CE2 1 
ATOM   7456  C CZ  . TYR D 2 119 ? -10.922 -17.999 -86.057  1.00 159.45 ? 119 TYR D CZ  1 
ATOM   7457  O OH  . TYR D 2 119 ? -11.549 -18.739 -87.034  1.00 157.01 ? 119 TYR D OH  1 
ATOM   7458  N N   . ASP D 2 120 ? -9.102  -12.823 -84.374  1.00 139.63 ? 120 ASP D N   1 
ATOM   7459  C CA  . ASP D 2 120 ? -9.614  -11.954 -85.428  1.00 144.96 ? 120 ASP D CA  1 
ATOM   7460  C C   . ASP D 2 120 ? -8.493  -11.206 -86.138  1.00 146.51 ? 120 ASP D C   1 
ATOM   7461  O O   . ASP D 2 120 ? -8.621  -10.889 -87.327  1.00 151.44 ? 120 ASP D O   1 
ATOM   7462  C CB  . ASP D 2 120 ? -10.632 -10.969 -84.851  1.00 145.13 ? 120 ASP D CB  1 
ATOM   7463  C CG  . ASP D 2 120 ? -11.917 -11.648 -84.413  1.00 148.50 ? 120 ASP D CG  1 
ATOM   7464  O OD1 . ASP D 2 120 ? -12.294 -12.665 -85.034  1.00 148.96 ? 120 ASP D OD1 1 
ATOM   7465  O OD2 . ASP D 2 120 ? -12.549 -11.166 -83.450  1.00 144.73 ? 120 ASP D OD2 1 
ATOM   7466  N N   . LYS D 2 121 ? -7.401  -10.902 -85.433  1.00 138.72 ? 121 LYS D N   1 
ATOM   7467  C CA  . LYS D 2 121 ? -6.255  -10.276 -86.085  1.00 144.32 ? 121 LYS D CA  1 
ATOM   7468  C C   . LYS D 2 121 ? -5.632  -11.206 -87.119  1.00 151.52 ? 121 LYS D C   1 
ATOM   7469  O O   . LYS D 2 121 ? -5.272  -10.772 -88.219  1.00 148.09 ? 121 LYS D O   1 
ATOM   7470  C CB  . LYS D 2 121 ? -5.215  -9.859  -85.045  1.00 137.24 ? 121 LYS D CB  1 
ATOM   7471  C CG  . LYS D 2 121 ? -5.621  -8.665  -84.196  1.00 137.22 ? 121 LYS D CG  1 
ATOM   7472  C CD  . LYS D 2 121 ? -4.516  -8.279  -83.225  1.00 134.96 ? 121 LYS D CD  1 
ATOM   7473  C CE  . LYS D 2 121 ? -3.232  -7.923  -83.959  1.00 121.41 ? 121 LYS D CE  1 
ATOM   7474  N NZ  . LYS D 2 121 ? -2.137  -7.550  -83.021  1.00 102.24 ? 121 LYS D NZ  1 
ATOM   7475  N N   . VAL D 2 122 ? -5.494  -12.491 -86.781  1.00 151.05 ? 122 VAL D N   1 
ATOM   7476  C CA  . VAL D 2 122 ? -4.932  -13.454 -87.724  1.00 148.94 ? 122 VAL D CA  1 
ATOM   7477  C C   . VAL D 2 122 ? -5.887  -13.685 -88.888  1.00 156.80 ? 122 VAL D C   1 
ATOM   7478  O O   . VAL D 2 122 ? -5.458  -13.852 -90.036  1.00 164.84 ? 122 VAL D O   1 
ATOM   7479  C CB  . VAL D 2 122 ? -4.585  -14.769 -87.002  1.00 140.39 ? 122 VAL D CB  1 
ATOM   7480  C CG1 . VAL D 2 122 ? -3.916  -15.743 -87.959  1.00 153.29 ? 122 VAL D CG1 1 
ATOM   7481  C CG2 . VAL D 2 122 ? -3.688  -14.495 -85.806  1.00 139.09 ? 122 VAL D CG2 1 
ATOM   7482  N N   . ARG D 2 123 ? -7.195  -13.701 -88.614  1.00 157.85 ? 123 ARG D N   1 
ATOM   7483  C CA  . ARG D 2 123 ? -8.175  -13.893 -89.679  1.00 153.76 ? 123 ARG D CA  1 
ATOM   7484  C C   . ARG D 2 123 ? -8.094  -12.771 -90.708  1.00 154.81 ? 123 ARG D C   1 
ATOM   7485  O O   . ARG D 2 123 ? -8.179  -13.019 -91.917  1.00 158.71 ? 123 ARG D O   1 
ATOM   7486  C CB  . ARG D 2 123 ? -9.580  -13.990 -89.081  1.00 150.09 ? 123 ARG D CB  1 
ATOM   7487  C CG  . ARG D 2 123 ? -10.669 -14.419 -90.056  1.00 146.58 ? 123 ARG D CG  1 
ATOM   7488  C CD  . ARG D 2 123 ? -11.390 -13.221 -90.655  1.00 148.63 ? 123 ARG D CD  1 
ATOM   7489  N NE  . ARG D 2 123 ? -11.827 -12.284 -89.626  1.00 155.71 ? 123 ARG D NE  1 
ATOM   7490  C CZ  . ARG D 2 123 ? -12.429 -11.129 -89.871  1.00 155.03 ? 123 ARG D CZ  1 
ATOM   7491  N NH1 . ARG D 2 123 ? -12.690 -10.734 -91.107  1.00 147.36 ? 123 ARG D NH1 1 
ATOM   7492  N NH2 . ARG D 2 123 ? -12.777 -10.349 -88.851  1.00 153.67 ? 123 ARG D NH2 1 
ATOM   7493  N N   . LEU D 2 124 ? -7.932  -11.528 -90.248  1.00 149.95 ? 124 LEU D N   1 
ATOM   7494  C CA  . LEU D 2 124 ? -7.709  -10.418 -91.167  1.00 151.27 ? 124 LEU D CA  1 
ATOM   7495  C C   . LEU D 2 124 ? -6.303  -10.427 -91.750  1.00 160.86 ? 124 LEU D C   1 
ATOM   7496  O O   . LEU D 2 124 ? -6.057  -9.752  -92.755  1.00 160.73 ? 124 LEU D O   1 
ATOM   7497  C CB  . LEU D 2 124 ? -7.969  -9.086  -90.460  1.00 146.39 ? 124 LEU D CB  1 
ATOM   7498  C CG  . LEU D 2 124 ? -9.429  -8.703  -90.212  1.00 144.70 ? 124 LEU D CG  1 
ATOM   7499  C CD1 . LEU D 2 124 ? -9.515  -7.481  -89.312  1.00 145.88 ? 124 LEU D CD1 1 
ATOM   7500  C CD2 . LEU D 2 124 ? -10.142 -8.448  -91.530  1.00 142.05 ? 124 LEU D CD2 1 
ATOM   7501  N N   . GLN D 2 125 ? -5.378  -11.171 -91.143  1.00 163.39 ? 125 GLN D N   1 
ATOM   7502  C CA  . GLN D 2 125 ? -4.004  -11.239 -91.622  1.00 165.78 ? 125 GLN D CA  1 
ATOM   7503  C C   . GLN D 2 125 ? -3.795  -12.307 -92.688  1.00 163.28 ? 125 GLN D C   1 
ATOM   7504  O O   . GLN D 2 125 ? -2.825  -12.219 -93.449  1.00 163.09 ? 125 GLN D O   1 
ATOM   7505  C CB  . GLN D 2 125 ? -3.052  -11.497 -90.448  1.00 166.68 ? 125 GLN D CB  1 
ATOM   7506  C CG  . GLN D 2 125 ? -1.586  -11.208 -90.742  1.00 167.50 ? 125 GLN D CG  1 
ATOM   7507  C CD  . GLN D 2 125 ? -1.303  -9.727  -90.909  1.00 171.48 ? 125 GLN D CD  1 
ATOM   7508  O OE1 . GLN D 2 125 ? -0.447  -9.333  -91.700  1.00 180.89 ? 125 GLN D OE1 1 
ATOM   7509  N NE2 . GLN D 2 125 ? -2.018  -8.899  -90.156  1.00 162.72 ? 125 GLN D NE2 1 
ATOM   7510  N N   . LEU D 2 126 ? -4.675  -13.303 -92.769  1.00 164.72 ? 126 LEU D N   1 
ATOM   7511  C CA  . LEU D 2 126 ? -4.540  -14.392 -93.729  1.00 166.61 ? 126 LEU D CA  1 
ATOM   7512  C C   . LEU D 2 126 ? -5.591  -14.339 -94.827  1.00 171.83 ? 126 LEU D C   1 
ATOM   7513  O O   . LEU D 2 126 ? -5.248  -14.374 -96.013  1.00 181.37 ? 126 LEU D O   1 
ATOM   7514  C CB  . LEU D 2 126 ? -4.610  -15.745 -93.005  1.00 167.09 ? 126 LEU D CB  1 
ATOM   7515  C CG  . LEU D 2 126 ? -3.699  -15.924 -91.787  1.00 169.03 ? 126 LEU D CG  1 
ATOM   7516  C CD1 . LEU D 2 126 ? -3.707  -17.371 -91.316  1.00 167.54 ? 126 LEU D CD1 1 
ATOM   7517  C CD2 . LEU D 2 126 ? -2.281  -15.454 -92.082  1.00 177.60 ? 126 LEU D CD2 1 
ATOM   7518  N N   . ARG D 2 127 ? -6.868  -14.267 -94.454  1.00 173.14 ? 127 ARG D N   1 
ATOM   7519  C CA  . ARG D 2 127 ? -7.994  -14.078 -95.382  1.00 176.24 ? 127 ARG D CA  1 
ATOM   7520  C C   . ARG D 2 127 ? -8.081  -15.301 -96.295  1.00 182.67 ? 127 ARG D C   1 
ATOM   7521  O O   . ARG D 2 127 ? -7.989  -16.434 -95.797  1.00 176.73 ? 127 ARG D O   1 
ATOM   7522  C CB  . ARG D 2 127 ? -7.835  -12.739 -96.089  1.00 168.54 ? 127 ARG D CB  1 
ATOM   7523  C CG  . ARG D 2 127 ? -7.820  -11.538 -95.163  1.00 164.51 ? 127 ARG D CG  1 
ATOM   7524  C CD  . ARG D 2 127 ? -7.952  -10.270 -95.974  1.00 163.42 ? 127 ARG D CD  1 
ATOM   7525  N NE  . ARG D 2 127 ? -9.018  -10.401 -96.960  1.00 171.92 ? 127 ARG D NE  1 
ATOM   7526  C CZ  . ARG D 2 127 ? -9.282  -9.512  -97.906  1.00 170.99 ? 127 ARG D CZ  1 
ATOM   7527  N NH1 . ARG D 2 127 ? -8.571  -8.404  -98.032  1.00 169.30 ? 127 ARG D NH1 1 
ATOM   7528  N NH2 . ARG D 2 127 ? -10.286 -9.740  -98.748  1.00 165.70 ? 127 ARG D NH2 1 
ATOM   7529  N N   . ASP D 2 128 ? -8.253  -15.131 -97.610  1.00 189.88 ? 128 ASP D N   1 
ATOM   7530  C CA  . ASP D 2 128 ? -8.461  -16.255 -98.517  1.00 194.37 ? 128 ASP D CA  1 
ATOM   7531  C C   . ASP D 2 128 ? -7.220  -17.118 -98.694  1.00 197.40 ? 128 ASP D C   1 
ATOM   7532  O O   . ASP D 2 128 ? -7.317  -18.192 -99.297  1.00 194.26 ? 128 ASP D O   1 
ATOM   7533  C CB  . ASP D 2 128 ? -8.939  -15.752 -99.883  1.00 190.76 ? 128 ASP D CB  1 
ATOM   7534  C CG  . ASP D 2 128 ? -7.999  -14.730 -100.497 1.00 188.32 ? 128 ASP D CG  1 
ATOM   7535  O OD1 . ASP D 2 128 ? -7.031  -14.322 -99.822  1.00 187.95 ? 128 ASP D OD1 1 
ATOM   7536  O OD2 . ASP D 2 128 ? -8.232  -14.334 -101.658 1.00 184.59 ? 128 ASP D OD2 1 
ATOM   7537  N N   . ASN D 2 129 ? -6.065  -16.679 -98.197  1.00 198.90 ? 129 ASN D N   1 
ATOM   7538  C CA  . ASN D 2 129 ? -4.860  -17.496 -98.226  1.00 194.74 ? 129 ASN D CA  1 
ATOM   7539  C C   . ASN D 2 129 ? -4.883  -18.609 -97.185  1.00 195.34 ? 129 ASN D C   1 
ATOM   7540  O O   . ASN D 2 129 ? -3.941  -19.407 -97.135  1.00 197.22 ? 129 ASN D O   1 
ATOM   7541  C CB  . ASN D 2 129 ? -3.622  -16.618 -98.019  1.00 187.01 ? 129 ASN D CB  1 
ATOM   7542  C CG  . ASN D 2 129 ? -3.596  -15.415 -98.945  1.00 182.07 ? 129 ASN D CG  1 
ATOM   7543  O OD1 . ASN D 2 129 ? -3.273  -14.303 -98.528  1.00 171.34 ? 129 ASN D OD1 1 
ATOM   7544  N ND2 . ASN D 2 129 ? -3.946  -15.632 -100.208 1.00 185.74 ? 129 ASN D ND2 1 
ATOM   7545  N N   . ALA D 2 130 ? -5.922  -18.676 -96.355  1.00 192.22 ? 130 ALA D N   1 
ATOM   7546  C CA  . ALA D 2 130 ? -6.028  -19.706 -95.334  1.00 190.17 ? 130 ALA D CA  1 
ATOM   7547  C C   . ALA D 2 130 ? -7.496  -20.024 -95.086  1.00 181.53 ? 130 ALA D C   1 
ATOM   7548  O O   . ALA D 2 130 ? -8.390  -19.245 -95.426  1.00 170.12 ? 130 ALA D O   1 
ATOM   7549  C CB  . ALA D 2 130 ? -5.344  -19.280 -94.030  1.00 187.89 ? 130 ALA D CB  1 
ATOM   7550  N N   . LYS D 2 131 ? -7.732  -21.189 -94.487  1.00 180.64 ? 131 LYS D N   1 
ATOM   7551  C CA  . LYS D 2 131 ? -9.065  -21.652 -94.140  1.00 176.34 ? 131 LYS D CA  1 
ATOM   7552  C C   . LYS D 2 131 ? -9.317  -21.416 -92.651  1.00 177.10 ? 131 LYS D C   1 
ATOM   7553  O O   . LYS D 2 131 ? -8.474  -20.879 -91.929  1.00 181.26 ? 131 LYS D O   1 
ATOM   7554  C CB  . LYS D 2 131 ? -9.219  -23.131 -94.509  1.00 174.89 ? 131 LYS D CB  1 
ATOM   7555  C CG  . LYS D 2 131 ? -10.631 -23.558 -94.892  1.00 168.25 ? 131 LYS D CG  1 
ATOM   7556  C CD  . LYS D 2 131 ? -10.675 -25.039 -95.247  1.00 159.79 ? 131 LYS D CD  1 
ATOM   7557  C CE  . LYS D 2 131 ? -12.032 -25.448 -95.800  1.00 145.19 ? 131 LYS D CE  1 
ATOM   7558  N NZ  . LYS D 2 131 ? -12.316 -24.805 -97.113  1.00 145.18 ? 131 LYS D NZ  1 
ATOM   7559  N N   . GLU D 2 132 ? -10.500 -21.818 -92.187  1.00 169.76 ? 132 GLU D N   1 
ATOM   7560  C CA  . GLU D 2 132 ? -10.864 -21.736 -90.774  1.00 158.78 ? 132 GLU D CA  1 
ATOM   7561  C C   . GLU D 2 132 ? -11.271 -23.127 -90.310  1.00 155.51 ? 132 GLU D C   1 
ATOM   7562  O O   . GLU D 2 132 ? -12.349 -23.612 -90.668  1.00 152.05 ? 132 GLU D O   1 
ATOM   7563  C CB  . GLU D 2 132 ? -11.994 -20.730 -90.546  1.00 155.49 ? 132 GLU D CB  1 
ATOM   7564  C CG  . GLU D 2 132 ? -11.734 -19.354 -91.139  1.00 157.90 ? 132 GLU D CG  1 
ATOM   7565  C CD  . GLU D 2 132 ? -12.734 -18.315 -90.666  1.00 153.01 ? 132 GLU D CD  1 
ATOM   7566  O OE1 . GLU D 2 132 ? -12.874 -18.138 -89.438  1.00 147.85 ? 132 GLU D OE1 1 
ATOM   7567  O OE2 . GLU D 2 132 ? -13.383 -17.679 -91.523  1.00 148.62 ? 132 GLU D OE2 1 
ATOM   7568  N N   . LEU D 2 133 ? -10.411 -23.769 -89.515  1.00 163.29 ? 133 LEU D N   1 
ATOM   7569  C CA  . LEU D 2 133 ? -10.685 -25.134 -89.074  1.00 167.00 ? 133 LEU D CA  1 
ATOM   7570  C C   . LEU D 2 133 ? -11.895 -25.188 -88.149  1.00 161.67 ? 133 LEU D C   1 
ATOM   7571  O O   . LEU D 2 133 ? -12.805 -26.001 -88.348  1.00 155.75 ? 133 LEU D O   1 
ATOM   7572  C CB  . LEU D 2 133 ? -9.454  -25.721 -88.382  1.00 168.66 ? 133 LEU D CB  1 
ATOM   7573  C CG  . LEU D 2 133 ? -8.237  -25.991 -89.267  1.00 173.44 ? 133 LEU D CG  1 
ATOM   7574  C CD1 . LEU D 2 133 ? -7.110  -26.599 -88.449  1.00 171.23 ? 133 LEU D CD1 1 
ATOM   7575  C CD2 . LEU D 2 133 ? -8.612  -26.898 -90.428  1.00 173.47 ? 133 LEU D CD2 1 
ATOM   7576  N N   . GLY D 2 134 ? -11.923 -24.332 -87.130  1.00 161.30 ? 134 GLY D N   1 
ATOM   7577  C CA  . GLY D 2 134 ? -13.033 -24.319 -86.200  1.00 152.70 ? 134 GLY D CA  1 
ATOM   7578  C C   . GLY D 2 134 ? -12.619 -24.198 -84.748  1.00 157.46 ? 134 GLY D C   1 
ATOM   7579  O O   . GLY D 2 134 ? -13.373 -23.668 -83.928  1.00 151.23 ? 134 GLY D O   1 
ATOM   7580  N N   . ASN D 2 135 ? -11.424 -24.688 -84.413  1.00 165.70 ? 135 ASN D N   1 
ATOM   7581  C CA  . ASN D 2 135 ? -10.906 -24.625 -83.052  1.00 159.87 ? 135 ASN D CA  1 
ATOM   7582  C C   . ASN D 2 135 ? -9.885  -23.506 -82.872  1.00 155.64 ? 135 ASN D C   1 
ATOM   7583  O O   . ASN D 2 135 ? -8.946  -23.640 -82.080  1.00 148.92 ? 135 ASN D O   1 
ATOM   7584  C CB  . ASN D 2 135 ? -10.300 -25.970 -82.648  1.00 157.24 ? 135 ASN D CB  1 
ATOM   7585  C CG  . ASN D 2 135 ? -9.109  -26.356 -83.502  1.00 155.72 ? 135 ASN D CG  1 
ATOM   7586  O OD1 . ASN D 2 135 ? -9.067  -26.066 -84.697  1.00 157.52 ? 135 ASN D OD1 1 
ATOM   7587  N ND2 . ASN D 2 135 ? -8.130  -27.012 -82.889  1.00 147.24 ? 135 ASN D ND2 1 
ATOM   7588  N N   . GLY D 2 136 ? -10.056 -22.397 -83.589  1.00 152.73 ? 136 GLY D N   1 
ATOM   7589  C CA  . GLY D 2 136 ? -9.149  -21.275 -83.489  1.00 150.04 ? 136 GLY D CA  1 
ATOM   7590  C C   . GLY D 2 136 ? -7.906  -21.369 -84.346  1.00 159.87 ? 136 GLY D C   1 
ATOM   7591  O O   . GLY D 2 136 ? -7.068  -20.460 -84.290  1.00 162.51 ? 136 GLY D O   1 
ATOM   7592  N N   . CYS D 2 137 ? -7.758  -22.427 -85.137  1.00 165.45 ? 137 CYS D N   1 
ATOM   7593  C CA  . CYS D 2 137 ? -6.587  -22.630 -85.974  1.00 171.02 ? 137 CYS D CA  1 
ATOM   7594  C C   . CYS D 2 137 ? -6.940  -22.406 -87.439  1.00 172.34 ? 137 CYS D C   1 
ATOM   7595  O O   . CYS D 2 137 ? -8.085  -22.598 -87.856  1.00 171.79 ? 137 CYS D O   1 
ATOM   7596  C CB  . CYS D 2 137 ? -6.016  -24.040 -85.787  1.00 170.61 ? 137 CYS D CB  1 
ATOM   7597  S SG  . CYS D 2 137 ? -5.590  -24.479 -84.081  1.00 169.62 ? 137 CYS D SG  1 
ATOM   7598  N N   . PHE D 2 138 ? -5.940  -22.000 -88.218  1.00 175.86 ? 138 PHE D N   1 
ATOM   7599  C CA  . PHE D 2 138 ? -6.103  -21.718 -89.637  1.00 181.97 ? 138 PHE D CA  1 
ATOM   7600  C C   . PHE D 2 138 ? -5.328  -22.736 -90.463  1.00 192.39 ? 138 PHE D C   1 
ATOM   7601  O O   . PHE D 2 138 ? -4.235  -23.161 -90.076  1.00 195.47 ? 138 PHE D O   1 
ATOM   7602  C CB  . PHE D 2 138 ? -5.620  -20.305 -89.978  1.00 179.55 ? 138 PHE D CB  1 
ATOM   7603  C CG  . PHE D 2 138 ? -6.404  -19.213 -89.308  1.00 173.56 ? 138 PHE D CG  1 
ATOM   7604  C CD1 . PHE D 2 138 ? -6.064  -18.775 -88.038  1.00 171.03 ? 138 PHE D CD1 1 
ATOM   7605  C CD2 . PHE D 2 138 ? -7.476  -18.616 -89.952  1.00 173.42 ? 138 PHE D CD2 1 
ATOM   7606  C CE1 . PHE D 2 138 ? -6.783  -17.768 -87.421  1.00 167.88 ? 138 PHE D CE1 1 
ATOM   7607  C CE2 . PHE D 2 138 ? -8.198  -17.608 -89.341  1.00 164.85 ? 138 PHE D CE2 1 
ATOM   7608  C CZ  . PHE D 2 138 ? -7.850  -17.183 -88.074  1.00 164.26 ? 138 PHE D CZ  1 
ATOM   7609  N N   . GLU D 2 139 ? -5.898  -23.124 -91.603  1.00 193.71 ? 139 GLU D N   1 
ATOM   7610  C CA  . GLU D 2 139 ? -5.252  -24.043 -92.536  1.00 194.67 ? 139 GLU D CA  1 
ATOM   7611  C C   . GLU D 2 139 ? -4.750  -23.238 -93.730  1.00 195.79 ? 139 GLU D C   1 
ATOM   7612  O O   . GLU D 2 139 ? -5.547  -22.765 -94.546  1.00 196.13 ? 139 GLU D O   1 
ATOM   7613  C CB  . GLU D 2 139 ? -6.219  -25.137 -92.981  1.00 193.48 ? 139 GLU D CB  1 
ATOM   7614  C CG  . GLU D 2 139 ? -5.609  -26.161 -93.927  1.00 195.76 ? 139 GLU D CG  1 
ATOM   7615  C CD  . GLU D 2 139 ? -4.885  -27.277 -93.197  1.00 196.03 ? 139 GLU D CD  1 
ATOM   7616  O OE1 . GLU D 2 139 ? -5.524  -27.959 -92.368  1.00 189.13 ? 139 GLU D OE1 1 
ATOM   7617  O OE2 . GLU D 2 139 ? -3.677  -27.470 -93.449  1.00 198.00 ? 139 GLU D OE2 1 
ATOM   7618  N N   . PHE D 2 140 ? -3.432  -23.087 -93.833  1.00 197.99 ? 140 PHE D N   1 
ATOM   7619  C CA  . PHE D 2 140 ? -2.848  -22.289 -94.903  1.00 203.74 ? 140 PHE D CA  1 
ATOM   7620  C C   . PHE D 2 140 ? -3.045  -22.953 -96.261  1.00 205.61 ? 140 PHE D C   1 
ATOM   7621  O O   . PHE D 2 140 ? -3.094  -24.180 -96.382  1.00 202.48 ? 140 PHE D O   1 
ATOM   7622  C CB  . PHE D 2 140 ? -1.356  -22.064 -94.656  1.00 206.35 ? 140 PHE D CB  1 
ATOM   7623  C CG  . PHE D 2 140 ? -1.035  -20.739 -94.027  1.00 203.27 ? 140 PHE D CG  1 
ATOM   7624  C CD1 . PHE D 2 140 ? -1.089  -19.573 -94.773  1.00 197.73 ? 140 PHE D CD1 1 
ATOM   7625  C CD2 . PHE D 2 140 ? -0.668  -20.660 -92.695  1.00 200.55 ? 140 PHE D CD2 1 
ATOM   7626  C CE1 . PHE D 2 140 ? -0.791  -18.352 -94.200  1.00 189.58 ? 140 PHE D CE1 1 
ATOM   7627  C CE2 . PHE D 2 140 ? -0.368  -19.442 -92.116  1.00 202.57 ? 140 PHE D CE2 1 
ATOM   7628  C CZ  . PHE D 2 140 ? -0.428  -18.288 -92.870  1.00 193.57 ? 140 PHE D CZ  1 
ATOM   7629  N N   . TYR D 2 141 ? -3.157  -22.117 -97.293  1.00 206.25 ? 141 TYR D N   1 
ATOM   7630  C CA  . TYR D 2 141 ? -3.246  -22.564 -98.676  1.00 203.57 ? 141 TYR D CA  1 
ATOM   7631  C C   . TYR D 2 141 ? -1.917  -22.436 -99.411  1.00 199.17 ? 141 TYR D C   1 
ATOM   7632  O O   . TYR D 2 141 ? -1.893  -22.456 -100.646 1.00 194.46 ? 141 TYR D O   1 
ATOM   7633  C CB  . TYR D 2 141 ? -4.334  -21.784 -99.417  1.00 202.12 ? 141 TYR D CB  1 
ATOM   7634  C CG  . TYR D 2 141 ? -5.746  -22.144 -99.011  1.00 199.44 ? 141 TYR D CG  1 
ATOM   7635  C CD1 . TYR D 2 141 ? -6.043  -23.393 -98.479  1.00 195.97 ? 141 TYR D CD1 1 
ATOM   7636  C CD2 . TYR D 2 141 ? -6.783  -21.234 -99.164  1.00 194.14 ? 141 TYR D CD2 1 
ATOM   7637  C CE1 . TYR D 2 141 ? -7.334  -23.723 -98.110  1.00 186.85 ? 141 TYR D CE1 1 
ATOM   7638  C CE2 . TYR D 2 141 ? -8.076  -21.555 -98.798  1.00 190.10 ? 141 TYR D CE2 1 
ATOM   7639  C CZ  . TYR D 2 141 ? -8.346  -22.800 -98.272  1.00 185.25 ? 141 TYR D CZ  1 
ATOM   7640  O OH  . TYR D 2 141 ? -9.633  -23.121 -97.908  1.00 174.90 ? 141 TYR D OH  1 
ATOM   7641  N N   . HIS D 2 142 ? -0.816  -22.287 -98.679  1.00 196.51 ? 142 HIS D N   1 
ATOM   7642  C CA  . HIS D 2 142 ? 0.503   -22.162 -99.284  1.00 197.97 ? 142 HIS D CA  1 
ATOM   7643  C C   . HIS D 2 142 ? 1.548   -22.518 -98.236  1.00 198.20 ? 142 HIS D C   1 
ATOM   7644  O O   . HIS D 2 142 ? 1.240   -22.682 -97.053  1.00 194.65 ? 142 HIS D O   1 
ATOM   7645  C CB  . HIS D 2 142 ? 0.734   -20.752 -99.838  1.00 192.79 ? 142 HIS D CB  1 
ATOM   7646  C CG  . HIS D 2 142 ? 0.612   -19.670 -98.810  1.00 194.88 ? 142 HIS D CG  1 
ATOM   7647  N ND1 . HIS D 2 142 ? 1.620   -19.371 -97.919  1.00 196.43 ? 142 HIS D ND1 1 
ATOM   7648  C CD2 . HIS D 2 142 ? -0.402  -18.817 -98.530  1.00 195.64 ? 142 HIS D CD2 1 
ATOM   7649  C CE1 . HIS D 2 142 ? 1.234   -18.380 -97.136  1.00 199.87 ? 142 HIS D CE1 1 
ATOM   7650  N NE2 . HIS D 2 142 ? 0.011   -18.025 -97.486  1.00 197.61 ? 142 HIS D NE2 1 
ATOM   7651  N N   . LYS D 2 143 ? 2.792   -22.640 -98.690  1.00 201.96 ? 143 LYS D N   1 
ATOM   7652  C CA  . LYS D 2 143 ? 3.890   -22.944 -97.783  1.00 197.27 ? 143 LYS D CA  1 
ATOM   7653  C C   . LYS D 2 143 ? 4.241   -21.714 -96.955  1.00 197.65 ? 143 LYS D C   1 
ATOM   7654  O O   . LYS D 2 143 ? 4.455   -20.626 -97.498  1.00 193.92 ? 143 LYS D O   1 
ATOM   7655  C CB  . LYS D 2 143 ? 5.110   -23.424 -98.568  1.00 186.13 ? 143 LYS D CB  1 
ATOM   7656  C CG  . LYS D 2 143 ? 4.863   -24.675 -99.398  1.00 171.85 ? 143 LYS D CG  1 
ATOM   7657  C CD  . LYS D 2 143 ? 4.606   -25.886 -98.516  1.00 164.70 ? 143 LYS D CD  1 
ATOM   7658  C CE  . LYS D 2 143 ? 4.150   -27.081 -99.340  1.00 144.59 ? 143 LYS D CE  1 
ATOM   7659  N NZ  . LYS D 2 143 ? 5.109   -27.414 -100.430 1.00 98.43  ? 143 LYS D NZ  1 
ATOM   7660  N N   . CYS D 2 144 ? 4.297   -21.891 -95.637  1.00 199.74 ? 144 CYS D N   1 
ATOM   7661  C CA  . CYS D 2 144 ? 4.611   -20.816 -94.703  1.00 202.44 ? 144 CYS D CA  1 
ATOM   7662  C C   . CYS D 2 144 ? 5.869   -21.184 -93.933  1.00 201.19 ? 144 CYS D C   1 
ATOM   7663  O O   . CYS D 2 144 ? 5.868   -22.149 -93.160  1.00 195.02 ? 144 CYS D O   1 
ATOM   7664  C CB  . CYS D 2 144 ? 3.444   -20.566 -93.743  1.00 197.94 ? 144 CYS D CB  1 
ATOM   7665  S SG  . CYS D 2 144 ? 3.671   -19.160 -92.629  1.00 183.18 ? 144 CYS D SG  1 
ATOM   7666  N N   . ASP D 2 145 ? 6.936   -20.420 -94.142  1.00 201.27 ? 145 ASP D N   1 
ATOM   7667  C CA  . ASP D 2 145 ? 8.209   -20.683 -93.486  1.00 194.94 ? 145 ASP D CA  1 
ATOM   7668  C C   . ASP D 2 145 ? 8.157   -20.183 -92.043  1.00 181.97 ? 145 ASP D C   1 
ATOM   7669  O O   . ASP D 2 145 ? 7.107   -19.793 -91.527  1.00 175.92 ? 145 ASP D O   1 
ATOM   7670  C CB  . ASP D 2 145 ? 9.351   -20.036 -94.265  1.00 191.98 ? 145 ASP D CB  1 
ATOM   7671  C CG  . ASP D 2 145 ? 9.467   -20.564 -95.681  1.00 194.06 ? 145 ASP D CG  1 
ATOM   7672  O OD1 . ASP D 2 145 ? 8.652   -21.429 -96.066  1.00 198.00 ? 145 ASP D OD1 1 
ATOM   7673  O OD2 . ASP D 2 145 ? 10.376  -20.114 -96.409  1.00 187.97 ? 145 ASP D OD2 1 
ATOM   7674  N N   . ASN D 2 146 ? 9.306   -20.196 -91.371  1.00 177.29 ? 146 ASN D N   1 
ATOM   7675  C CA  . ASN D 2 146 ? 9.436   -19.598 -90.051  1.00 173.73 ? 146 ASN D CA  1 
ATOM   7676  C C   . ASN D 2 146 ? 9.730   -18.106 -90.119  1.00 175.16 ? 146 ASN D C   1 
ATOM   7677  O O   . ASN D 2 146 ? 9.877   -17.466 -89.072  1.00 168.25 ? 146 ASN D O   1 
ATOM   7678  C CB  . ASN D 2 146 ? 10.528  -20.316 -89.251  1.00 166.98 ? 146 ASN D CB  1 
ATOM   7679  C CG  . ASN D 2 146 ? 10.155  -21.748 -88.918  1.00 171.49 ? 146 ASN D CG  1 
ATOM   7680  O OD1 . ASN D 2 146 ? 9.313   -22.353 -89.583  1.00 167.29 ? 146 ASN D OD1 1 
ATOM   7681  N ND2 . ASN D 2 146 ? 10.778  -22.296 -87.881  1.00 167.40 ? 146 ASN D ND2 1 
ATOM   7682  N N   . GLU D 2 147 ? 9.831   -17.547 -91.324  1.00 181.90 ? 147 GLU D N   1 
ATOM   7683  C CA  . GLU D 2 147 ? 9.934   -16.109 -91.525  1.00 179.40 ? 147 GLU D CA  1 
ATOM   7684  C C   . GLU D 2 147 ? 8.628   -15.484 -91.990  1.00 181.71 ? 147 GLU D C   1 
ATOM   7685  O O   . GLU D 2 147 ? 8.394   -14.298 -91.735  1.00 177.21 ? 147 GLU D O   1 
ATOM   7686  C CB  . GLU D 2 147 ? 11.035  -15.796 -92.544  1.00 180.29 ? 147 GLU D CB  1 
ATOM   7687  C CG  . GLU D 2 147 ? 12.419  -16.254 -92.113  1.00 176.74 ? 147 GLU D CG  1 
ATOM   7688  C CD  . GLU D 2 147 ? 13.376  -16.390 -93.280  1.00 174.86 ? 147 GLU D CD  1 
ATOM   7689  O OE1 . GLU D 2 147 ? 12.902  -16.567 -94.422  1.00 182.91 ? 147 GLU D OE1 1 
ATOM   7690  O OE2 . GLU D 2 147 ? 14.603  -16.320 -93.056  1.00 164.89 ? 147 GLU D OE2 1 
ATOM   7691  N N   . CYS D 2 148 ? 7.776   -16.255 -92.671  1.00 186.64 ? 148 CYS D N   1 
ATOM   7692  C CA  . CYS D 2 148 ? 6.457   -15.757 -93.044  1.00 186.87 ? 148 CYS D CA  1 
ATOM   7693  C C   . CYS D 2 148 ? 5.519   -15.713 -91.845  1.00 180.26 ? 148 CYS D C   1 
ATOM   7694  O O   . CYS D 2 148 ? 4.612   -14.874 -91.800  1.00 174.22 ? 148 CYS D O   1 
ATOM   7695  C CB  . CYS D 2 148 ? 5.864   -16.623 -94.155  1.00 190.92 ? 148 CYS D CB  1 
ATOM   7696  S SG  . CYS D 2 148 ? 4.216   -16.122 -94.711  1.00 193.78 ? 148 CYS D SG  1 
ATOM   7697  N N   . MET D 2 149 ? 5.717   -16.604 -90.869  1.00 181.00 ? 149 MET D N   1 
ATOM   7698  C CA  . MET D 2 149 ? 4.867   -16.591 -89.685  1.00 170.27 ? 149 MET D CA  1 
ATOM   7699  C C   . MET D 2 149 ? 5.217   -15.432 -88.760  1.00 169.94 ? 149 MET D C   1 
ATOM   7700  O O   . MET D 2 149 ? 4.336   -14.903 -88.072  1.00 169.88 ? 149 MET D O   1 
ATOM   7701  C CB  . MET D 2 149 ? 4.967   -17.925 -88.940  1.00 168.28 ? 149 MET D CB  1 
ATOM   7702  C CG  . MET D 2 149 ? 5.794   -17.880 -87.664  1.00 164.55 ? 149 MET D CG  1 
ATOM   7703  S SD  . MET D 2 149 ? 5.472   -19.274 -86.570  1.00 163.10 ? 149 MET D SD  1 
ATOM   7704  C CE  . MET D 2 149 ? 6.116   -20.620 -87.554  1.00 160.01 ? 149 MET D CE  1 
ATOM   7705  N N   . GLU D 2 150 ? 6.490   -15.028 -88.717  1.00 173.20 ? 150 GLU D N   1 
ATOM   7706  C CA  . GLU D 2 150 ? 6.853   -13.862 -87.921  1.00 169.74 ? 150 GLU D CA  1 
ATOM   7707  C C   . GLU D 2 150 ? 6.292   -12.588 -88.538  1.00 163.26 ? 150 GLU D C   1 
ATOM   7708  O O   . GLU D 2 150 ? 6.067   -11.598 -87.833  1.00 157.19 ? 150 GLU D O   1 
ATOM   7709  C CB  . GLU D 2 150 ? 8.371   -13.768 -87.771  1.00 167.79 ? 150 GLU D CB  1 
ATOM   7710  C CG  . GLU D 2 150 ? 8.817   -12.775 -86.713  1.00 163.78 ? 150 GLU D CG  1 
ATOM   7711  C CD  . GLU D 2 150 ? 8.228   -13.079 -85.349  1.00 165.49 ? 150 GLU D CD  1 
ATOM   7712  O OE1 . GLU D 2 150 ? 8.431   -14.205 -84.848  1.00 157.37 ? 150 GLU D OE1 1 
ATOM   7713  O OE2 . GLU D 2 150 ? 7.552   -12.195 -84.782  1.00 166.06 ? 150 GLU D OE2 1 
ATOM   7714  N N   . SER D 2 151 ? 6.066   -12.597 -89.853  1.00 167.27 ? 151 SER D N   1 
ATOM   7715  C CA  . SER D 2 151 ? 5.337   -11.509 -90.492  1.00 164.35 ? 151 SER D CA  1 
ATOM   7716  C C   . SER D 2 151 ? 3.871   -11.498 -90.074  1.00 167.96 ? 151 SER D C   1 
ATOM   7717  O O   . SER D 2 151 ? 3.224   -10.444 -90.103  1.00 163.97 ? 151 SER D O   1 
ATOM   7718  C CB  . SER D 2 151 ? 5.457   -11.626 -92.009  1.00 165.78 ? 151 SER D CB  1 
ATOM   7719  O OG  . SER D 2 151 ? 4.450   -10.871 -92.652  1.00 162.84 ? 151 SER D OG  1 
ATOM   7720  N N   . VAL D 2 152 ? 3.332   -12.656 -89.692  1.00 174.78 ? 152 VAL D N   1 
ATOM   7721  C CA  . VAL D 2 152 ? 1.961   -12.718 -89.200  1.00 170.78 ? 152 VAL D CA  1 
ATOM   7722  C C   . VAL D 2 152 ? 1.896   -12.316 -87.731  1.00 165.83 ? 152 VAL D C   1 
ATOM   7723  O O   . VAL D 2 152 ? 0.972   -11.611 -87.311  1.00 162.02 ? 152 VAL D O   1 
ATOM   7724  C CB  . VAL D 2 152 ? 1.379   -14.125 -89.433  1.00 172.43 ? 152 VAL D CB  1 
ATOM   7725  C CG1 . VAL D 2 152 ? -0.016  -14.235 -88.836  1.00 160.24 ? 152 VAL D CG1 1 
ATOM   7726  C CG2 . VAL D 2 152 ? 1.351   -14.446 -90.921  1.00 176.52 ? 152 VAL D CG2 1 
ATOM   7727  N N   . ARG D 2 153 ? 2.873   -12.752 -86.930  1.00 165.50 ? 153 ARG D N   1 
ATOM   7728  C CA  . ARG D 2 153 ? 2.858   -12.443 -85.502  1.00 154.85 ? 153 ARG D CA  1 
ATOM   7729  C C   . ARG D 2 153 ? 2.962   -10.942 -85.258  1.00 158.83 ? 153 ARG D C   1 
ATOM   7730  O O   . ARG D 2 153 ? 2.200   -10.378 -84.464  1.00 150.94 ? 153 ARG D O   1 
ATOM   7731  C CB  . ARG D 2 153 ? 3.989   -13.182 -84.787  1.00 147.61 ? 153 ARG D CB  1 
ATOM   7732  C CG  . ARG D 2 153 ? 3.856   -14.693 -84.792  1.00 146.60 ? 153 ARG D CG  1 
ATOM   7733  C CD  . ARG D 2 153 ? 4.469   -15.284 -83.534  1.00 149.01 ? 153 ARG D CD  1 
ATOM   7734  N NE  . ARG D 2 153 ? 4.913   -16.659 -83.727  1.00 155.41 ? 153 ARG D NE  1 
ATOM   7735  C CZ  . ARG D 2 153 ? 6.146   -17.001 -84.074  1.00 166.16 ? 153 ARG D CZ  1 
ATOM   7736  N NH1 . ARG D 2 153 ? 7.082   -16.090 -84.286  1.00 167.19 ? 153 ARG D NH1 1 
ATOM   7737  N NH2 . ARG D 2 153 ? 6.449   -18.289 -84.211  1.00 161.32 ? 153 ARG D NH2 1 
ATOM   7738  N N   . ASN D 2 154 ? 3.900   -10.274 -85.931  1.00 155.41 ? 154 ASN D N   1 
ATOM   7739  C CA  . ASN D 2 154 ? 3.997   -8.826  -85.803  1.00 154.53 ? 154 ASN D CA  1 
ATOM   7740  C C   . ASN D 2 154 ? 2.961   -8.094  -86.647  1.00 156.95 ? 154 ASN D C   1 
ATOM   7741  O O   . ASN D 2 154 ? 2.802   -6.879  -86.489  1.00 152.62 ? 154 ASN D O   1 
ATOM   7742  C CB  . ASN D 2 154 ? 5.409   -8.340  -86.162  1.00 154.24 ? 154 ASN D CB  1 
ATOM   7743  C CG  . ASN D 2 154 ? 5.782   -8.603  -87.613  1.00 158.49 ? 154 ASN D CG  1 
ATOM   7744  O OD1 . ASN D 2 154 ? 4.975   -9.091  -88.401  1.00 163.23 ? 154 ASN D OD1 1 
ATOM   7745  N ND2 . ASN D 2 154 ? 7.016   -8.268  -87.972  1.00 148.45 ? 154 ASN D ND2 1 
ATOM   7746  N N   . GLY D 2 155 ? 2.261   -8.802  -87.532  1.00 157.41 ? 155 GLY D N   1 
ATOM   7747  C CA  . GLY D 2 155 ? 1.211   -8.208  -88.335  1.00 159.21 ? 155 GLY D CA  1 
ATOM   7748  C C   . GLY D 2 155 ? 1.713   -7.325  -89.457  1.00 160.86 ? 155 GLY D C   1 
ATOM   7749  O O   . GLY D 2 155 ? 1.458   -6.117  -89.462  1.00 152.57 ? 155 GLY D O   1 
ATOM   7750  N N   . THR D 2 156 ? 2.432   -7.913  -90.419  1.00 167.69 ? 156 THR D N   1 
ATOM   7751  C CA  . THR D 2 156 ? 2.926   -7.145  -91.555  1.00 170.50 ? 156 THR D CA  1 
ATOM   7752  C C   . THR D 2 156 ? 2.815   -7.896  -92.879  1.00 173.52 ? 156 THR D C   1 
ATOM   7753  O O   . THR D 2 156 ? 3.390   -7.441  -93.877  1.00 173.91 ? 156 THR D O   1 
ATOM   7754  C CB  . THR D 2 156 ? 4.383   -6.716  -91.327  1.00 162.70 ? 156 THR D CB  1 
ATOM   7755  O OG1 . THR D 2 156 ? 4.769   -5.773  -92.335  1.00 154.05 ? 156 THR D OG1 1 
ATOM   7756  C CG2 . THR D 2 156 ? 5.315   -7.919  -91.384  1.00 156.42 ? 156 THR D CG2 1 
ATOM   7757  N N   . TYR D 2 157 ? 2.098   -9.018  -92.928  1.00 173.79 ? 157 TYR D N   1 
ATOM   7758  C CA  . TYR D 2 157 ? 1.968   -9.768  -94.171  1.00 174.22 ? 157 TYR D CA  1 
ATOM   7759  C C   . TYR D 2 157 ? 1.225   -8.950  -95.220  1.00 180.46 ? 157 TYR D C   1 
ATOM   7760  O O   . TYR D 2 157 ? 0.259   -8.246  -94.917  1.00 182.15 ? 157 TYR D O   1 
ATOM   7761  C CB  . TYR D 2 157 ? 1.243   -11.093 -93.923  1.00 172.92 ? 157 TYR D CB  1 
ATOM   7762  C CG  . TYR D 2 157 ? 0.687   -11.732 -95.178  1.00 178.52 ? 157 TYR D CG  1 
ATOM   7763  C CD1 . TYR D 2 157 ? 1.501   -12.465 -96.031  1.00 179.93 ? 157 TYR D CD1 1 
ATOM   7764  C CD2 . TYR D 2 157 ? -0.656  -11.600 -95.509  1.00 181.26 ? 157 TYR D CD2 1 
ATOM   7765  C CE1 . TYR D 2 157 ? 0.992   -13.047 -97.179  1.00 180.22 ? 157 TYR D CE1 1 
ATOM   7766  C CE2 . TYR D 2 157 ? -1.172  -12.177 -96.651  1.00 181.22 ? 157 TYR D CE2 1 
ATOM   7767  C CZ  . TYR D 2 157 ? -0.346  -12.899 -97.482  1.00 180.56 ? 157 TYR D CZ  1 
ATOM   7768  O OH  . TYR D 2 157 ? -0.866  -13.472 -98.619  1.00 179.58 ? 157 TYR D OH  1 
ATOM   7769  N N   . ASP D 2 158 ? 1.684   -9.053  -96.465  1.00 185.00 ? 158 ASP D N   1 
ATOM   7770  C CA  . ASP D 2 158 ? 1.107   -8.315  -97.576  1.00 187.67 ? 158 ASP D CA  1 
ATOM   7771  C C   . ASP D 2 158 ? 0.774   -9.276  -98.709  1.00 188.03 ? 158 ASP D C   1 
ATOM   7772  O O   . ASP D 2 158 ? 1.394   -10.333 -98.853  1.00 189.92 ? 158 ASP D O   1 
ATOM   7773  C CB  . ASP D 2 158 ? 2.062   -7.218  -98.071  1.00 187.96 ? 158 ASP D CB  1 
ATOM   7774  C CG  . ASP D 2 158 ? 1.338   -6.088  -98.777  1.00 189.45 ? 158 ASP D CG  1 
ATOM   7775  O OD1 . ASP D 2 158 ? 0.090   -6.106  -98.808  1.00 187.07 ? 158 ASP D OD1 1 
ATOM   7776  O OD2 . ASP D 2 158 ? 2.019   -5.184  -99.305  1.00 190.85 ? 158 ASP D OD2 1 
ATOM   7777  N N   . TYR D 2 159 ? -0.225  -8.896  -99.506  1.00 187.77 ? 159 TYR D N   1 
ATOM   7778  C CA  . TYR D 2 159 ? -0.634  -9.721  -100.641 1.00 186.74 ? 159 TYR D CA  1 
ATOM   7779  C C   . TYR D 2 159 ? 0.490   -10.005 -101.635 1.00 185.07 ? 159 TYR D C   1 
ATOM   7780  O O   . TYR D 2 159 ? 0.511   -11.121 -102.185 1.00 180.39 ? 159 TYR D O   1 
ATOM   7781  C CB  . TYR D 2 159 ? -1.831  -9.070  -101.345 1.00 182.32 ? 159 TYR D CB  1 
ATOM   7782  C CG  . TYR D 2 159 ? -3.030  -8.880  -100.445 1.00 179.36 ? 159 TYR D CG  1 
ATOM   7783  C CD1 . TYR D 2 159 ? -3.241  -9.712  -99.352  1.00 177.57 ? 159 TYR D CD1 1 
ATOM   7784  C CD2 . TYR D 2 159 ? -3.946  -7.865  -100.683 1.00 176.22 ? 159 TYR D CD2 1 
ATOM   7785  C CE1 . TYR D 2 159 ? -4.330  -9.539  -98.524  1.00 178.36 ? 159 TYR D CE1 1 
ATOM   7786  C CE2 . TYR D 2 159 ? -5.039  -7.685  -99.860  1.00 175.11 ? 159 TYR D CE2 1 
ATOM   7787  C CZ  . TYR D 2 159 ? -5.226  -8.525  -98.783  1.00 182.12 ? 159 TYR D CZ  1 
ATOM   7788  O OH  . TYR D 2 159 ? -6.313  -8.348  -97.961  1.00 182.38 ? 159 TYR D OH  1 
ATOM   7789  N N   . PRO D 2 160 ? 1.402   -9.069  -101.949 1.00 185.09 ? 160 PRO D N   1 
ATOM   7790  C CA  . PRO D 2 160 ? 2.538   -9.418  -102.821 1.00 179.08 ? 160 PRO D CA  1 
ATOM   7791  C C   . PRO D 2 160 ? 3.251   -10.708 -102.449 1.00 183.91 ? 160 PRO D C   1 
ATOM   7792  O O   . PRO D 2 160 ? 3.713   -11.431 -103.342 1.00 183.27 ? 160 PRO D O   1 
ATOM   7793  C CB  . PRO D 2 160 ? 3.462   -8.207  -102.658 1.00 172.67 ? 160 PRO D CB  1 
ATOM   7794  C CG  . PRO D 2 160 ? 2.527   -7.076  -102.462 1.00 172.43 ? 160 PRO D CG  1 
ATOM   7795  C CD  . PRO D 2 160 ? 1.316   -7.610  -101.746 1.00 182.77 ? 160 PRO D CD  1 
ATOM   7796  N N   . GLN D 2 161 ? 3.363   -11.016 -101.155 1.00 187.12 ? 161 GLN D N   1 
ATOM   7797  C CA  . GLN D 2 161 ? 3.999   -12.264 -100.747 1.00 184.50 ? 161 GLN D CA  1 
ATOM   7798  C C   . GLN D 2 161 ? 3.200   -13.476 -101.215 1.00 186.89 ? 161 GLN D C   1 
ATOM   7799  O O   . GLN D 2 161 ? 3.774   -14.446 -101.726 1.00 187.42 ? 161 GLN D O   1 
ATOM   7800  C CB  . GLN D 2 161 ? 4.181   -12.293 -99.229  1.00 181.86 ? 161 GLN D CB  1 
ATOM   7801  C CG  . GLN D 2 161 ? 5.398   -11.528 -98.724  1.00 183.40 ? 161 GLN D CG  1 
ATOM   7802  C CD  . GLN D 2 161 ? 5.234   -10.021 -98.808  1.00 190.76 ? 161 GLN D CD  1 
ATOM   7803  O OE1 . GLN D 2 161 ? 4.163   -9.517  -99.146  1.00 192.83 ? 161 GLN D OE1 1 
ATOM   7804  N NE2 . GLN D 2 161 ? 6.300   -9.293  -98.495  1.00 191.20 ? 161 GLN D NE2 1 
ATOM   7805  N N   . TYR D 2 162 ? 1.875   -13.442 -101.056 1.00 185.01 ? 162 TYR D N   1 
ATOM   7806  C CA  . TYR D 2 162 ? 1.029   -14.569 -101.450 1.00 187.48 ? 162 TYR D CA  1 
ATOM   7807  C C   . TYR D 2 162 ? -0.309  -14.015 -101.935 1.00 185.22 ? 162 TYR D C   1 
ATOM   7808  O O   . TYR D 2 162 ? -1.200  -13.744 -101.125 1.00 189.37 ? 162 TYR D O   1 
ATOM   7809  C CB  . TYR D 2 162 ? 0.832   -15.545 -100.296 1.00 190.82 ? 162 TYR D CB  1 
ATOM   7810  C CG  . TYR D 2 162 ? 2.100   -16.185 -99.778  1.00 194.09 ? 162 TYR D CG  1 
ATOM   7811  C CD1 . TYR D 2 162 ? 2.600   -17.345 -100.355 1.00 193.20 ? 162 TYR D CD1 1 
ATOM   7812  C CD2 . TYR D 2 162 ? 2.789   -15.638 -98.703  1.00 193.19 ? 162 TYR D CD2 1 
ATOM   7813  C CE1 . TYR D 2 162 ? 3.756   -17.936 -99.881  1.00 194.97 ? 162 TYR D CE1 1 
ATOM   7814  C CE2 . TYR D 2 162 ? 3.946   -16.222 -98.224  1.00 195.06 ? 162 TYR D CE2 1 
ATOM   7815  C CZ  . TYR D 2 162 ? 4.424   -17.371 -98.816  1.00 193.14 ? 162 TYR D CZ  1 
ATOM   7816  O OH  . TYR D 2 162 ? 5.575   -17.956 -98.341  1.00 185.74 ? 162 TYR D OH  1 
ATOM   7817  N N   . SER D 2 163 ? -0.440  -13.847 -103.251 1.00 185.12 ? 163 SER D N   1 
ATOM   7818  C CA  . SER D 2 163 ? -1.714  -13.476 -103.860 1.00 183.28 ? 163 SER D CA  1 
ATOM   7819  C C   . SER D 2 163 ? -2.241  -14.573 -104.775 1.00 182.05 ? 163 SER D C   1 
ATOM   7820  O O   . SER D 2 163 ? -3.361  -15.053 -104.574 1.00 180.89 ? 163 SER D O   1 
ATOM   7821  C CB  . SER D 2 163 ? -1.573  -12.155 -104.628 1.00 174.74 ? 163 SER D CB  1 
ATOM   7822  O OG  . SER D 2 163 ? -2.770  -11.843 -105.320 1.00 163.92 ? 163 SER D OG  1 
ATOM   7823  N N   . GLU D 2 164 ? -1.463  -14.986 -105.774 1.00 180.95 ? 164 GLU D N   1 
ATOM   7824  C CA  . GLU D 2 164 ? -1.826  -16.096 -106.647 1.00 180.68 ? 164 GLU D CA  1 
ATOM   7825  C C   . GLU D 2 164 ? -1.235  -17.421 -106.193 1.00 184.32 ? 164 GLU D C   1 
ATOM   7826  O O   . GLU D 2 164 ? -1.814  -18.475 -106.477 1.00 184.89 ? 164 GLU D O   1 
ATOM   7827  C CB  . GLU D 2 164 ? -1.375  -15.805 -108.084 1.00 176.30 ? 164 GLU D CB  1 
ATOM   7828  C CG  . GLU D 2 164 ? -2.019  -16.684 -109.152 1.00 179.31 ? 164 GLU D CG  1 
ATOM   7829  C CD  . GLU D 2 164 ? -1.285  -17.993 -109.369 1.00 182.26 ? 164 GLU D CD  1 
ATOM   7830  O OE1 . GLU D 2 164 ? -0.108  -18.093 -108.962 1.00 185.51 ? 164 GLU D OE1 1 
ATOM   7831  O OE2 . GLU D 2 164 ? -1.888  -18.924 -109.944 1.00 178.04 ? 164 GLU D OE2 1 
ATOM   7832  N N   . GLU D 2 165 ? -0.109  -17.383 -105.477 1.00 179.94 ? 165 GLU D N   1 
ATOM   7833  C CA  . GLU D 2 165 ? 0.527   -18.611 -105.013 1.00 180.67 ? 165 GLU D CA  1 
ATOM   7834  C C   . GLU D 2 165 ? -0.391  -19.393 -104.083 1.00 182.30 ? 165 GLU D C   1 
ATOM   7835  O O   . GLU D 2 165 ? -0.482  -20.622 -104.178 1.00 179.31 ? 165 GLU D O   1 
ATOM   7836  C CB  . GLU D 2 165 ? 1.844   -18.276 -104.313 1.00 179.11 ? 165 GLU D CB  1 
ATOM   7837  C CG  . GLU D 2 165 ? 2.572   -19.471 -103.730 1.00 177.06 ? 165 GLU D CG  1 
ATOM   7838  C CD  . GLU D 2 165 ? 3.867   -19.078 -103.050 1.00 180.45 ? 165 GLU D CD  1 
ATOM   7839  O OE1 . GLU D 2 165 ? 4.211   -17.877 -103.076 1.00 179.42 ? 165 GLU D OE1 1 
ATOM   7840  O OE2 . GLU D 2 165 ? 4.540   -19.967 -102.489 1.00 186.72 ? 165 GLU D OE2 1 
ATOM   7841  N N   . ALA D 2 166 ? -1.077  -18.697 -103.175 1.00 181.11 ? 166 ALA D N   1 
ATOM   7842  C CA  . ALA D 2 166 ? -2.042  -19.366 -102.311 1.00 185.32 ? 166 ALA D CA  1 
ATOM   7843  C C   . ALA D 2 166 ? -3.234  -19.891 -103.101 1.00 189.56 ? 166 ALA D C   1 
ATOM   7844  O O   . ALA D 2 166 ? -3.786  -20.942 -102.759 1.00 191.16 ? 166 ALA D O   1 
ATOM   7845  C CB  . ALA D 2 166 ? -2.513  -18.417 -101.211 1.00 186.48 ? 166 ALA D CB  1 
ATOM   7846  N N   . ARG D 2 167 ? -3.643  -19.176 -104.153 1.00 188.27 ? 167 ARG D N   1 
ATOM   7847  C CA  . ARG D 2 167 ? -4.788  -19.614 -104.946 1.00 189.16 ? 167 ARG D CA  1 
ATOM   7848  C C   . ARG D 2 167 ? -4.515  -20.935 -105.653 1.00 183.41 ? 167 ARG D C   1 
ATOM   7849  O O   . ARG D 2 167 ? -5.451  -21.696 -105.923 1.00 178.00 ? 167 ARG D O   1 
ATOM   7850  C CB  . ARG D 2 167 ? -5.171  -18.536 -105.963 1.00 186.37 ? 167 ARG D CB  1 
ATOM   7851  C CG  . ARG D 2 167 ? -5.730  -17.268 -105.336 1.00 190.06 ? 167 ARG D CG  1 
ATOM   7852  C CD  . ARG D 2 167 ? -6.559  -16.455 -106.324 1.00 185.83 ? 167 ARG D CD  1 
ATOM   7853  N NE  . ARG D 2 167 ? -5.750  -15.591 -107.175 1.00 179.59 ? 167 ARG D NE  1 
ATOM   7854  C CZ  . ARG D 2 167 ? -5.463  -15.839 -108.446 1.00 170.62 ? 167 ARG D CZ  1 
ATOM   7855  N NH1 . ARG D 2 167 ? -5.889  -16.936 -109.049 1.00 166.01 ? 167 ARG D NH1 1 
ATOM   7856  N NH2 . ARG D 2 167 ? -4.738  -14.959 -109.130 1.00 165.29 ? 167 ARG D NH2 1 
ATOM   7857  N N   . LEU D 2 168 ? -3.251  -21.222 -105.966 1.00 183.42 ? 168 LEU D N   1 
ATOM   7858  C CA  . LEU D 2 168 ? -2.899  -22.475 -106.622 1.00 185.65 ? 168 LEU D CA  1 
ATOM   7859  C C   . LEU D 2 168 ? -3.240  -23.672 -105.744 1.00 184.24 ? 168 LEU D C   1 
ATOM   7860  O O   . LEU D 2 168 ? -4.142  -24.448 -106.074 1.00 185.87 ? 168 LEU D O   1 
ATOM   7861  C CB  . LEU D 2 168 ? -1.411  -22.493 -106.980 1.00 186.90 ? 168 LEU D CB  1 
ATOM   7862  C CG  . LEU D 2 168 ? -0.979  -21.621 -108.160 1.00 182.63 ? 168 LEU D CG  1 
ATOM   7863  C CD1 . LEU D 2 168 ? 0.537   -21.586 -108.272 1.00 175.52 ? 168 LEU D CD1 1 
ATOM   7864  C CD2 . LEU D 2 168 ? -1.600  -22.134 -109.450 1.00 172.21 ? 168 LEU D CD2 1 
ATOM   7865  N N   . LYS D 2 169 ? -2.551  -23.805 -104.606 1.00 181.19 ? 169 LYS D N   1 
ATOM   7866  C CA  . LYS D 2 169 ? -2.770  -24.950 -103.727 1.00 179.84 ? 169 LYS D CA  1 
ATOM   7867  C C   . LYS D 2 169 ? -4.202  -24.993 -103.209 1.00 184.54 ? 169 LYS D C   1 
ATOM   7868  O O   . LYS D 2 169 ? -4.719  -26.072 -102.897 1.00 182.14 ? 169 LYS D O   1 
ATOM   7869  C CB  . LYS D 2 169 ? -1.774  -24.909 -102.566 1.00 172.19 ? 169 LYS D CB  1 
ATOM   7870  C CG  . LYS D 2 169 ? -1.823  -26.100 -101.618 1.00 167.06 ? 169 LYS D CG  1 
ATOM   7871  C CD  . LYS D 2 169 ? -1.331  -27.373 -102.287 1.00 152.93 ? 169 LYS D CD  1 
ATOM   7872  C CE  . LYS D 2 169 ? -1.065  -28.464 -101.260 1.00 142.23 ? 169 LYS D CE  1 
ATOM   7873  N NZ  . LYS D 2 169 ? -2.263  -28.754 -100.425 1.00 142.45 ? 169 LYS D NZ  1 
ATOM   7874  N N   . ARG D 2 170 ? -4.856  -23.833 -103.113 1.00 185.15 ? 170 ARG D N   1 
ATOM   7875  C CA  . ARG D 2 170 ? -6.267  -23.797 -102.745 1.00 183.22 ? 170 ARG D CA  1 
ATOM   7876  C C   . ARG D 2 170 ? -7.123  -24.511 -103.784 1.00 177.54 ? 170 ARG D C   1 
ATOM   7877  O O   . ARG D 2 170 ? -7.976  -25.339 -103.442 1.00 169.53 ? 170 ARG D O   1 
ATOM   7878  C CB  . ARG D 2 170 ? -6.718  -22.346 -102.582 1.00 188.52 ? 170 ARG D CB  1 
ATOM   7879  C CG  . ARG D 2 170 ? -8.214  -22.157 -102.408 1.00 185.80 ? 170 ARG D CG  1 
ATOM   7880  C CD  . ARG D 2 170 ? -8.595  -20.725 -102.735 1.00 179.72 ? 170 ARG D CD  1 
ATOM   7881  N NE  . ARG D 2 170 ? -7.614  -19.783 -102.211 1.00 190.14 ? 170 ARG D NE  1 
ATOM   7882  C CZ  . ARG D 2 170 ? -7.565  -18.496 -102.526 1.00 192.45 ? 170 ARG D CZ  1 
ATOM   7883  N NH1 . ARG D 2 170 ? -8.433  -17.957 -103.367 1.00 188.34 ? 170 ARG D NH1 1 
ATOM   7884  N NH2 . ARG D 2 170 ? -6.619  -17.732 -101.988 1.00 195.29 ? 170 ARG D NH2 1 
ATOM   7885  N N   . GLU D 2 171 ? -6.908  -24.201 -105.064 1.00 177.54 ? 171 GLU D N   1 
ATOM   7886  C CA  . GLU D 2 171 ? -7.679  -24.825 -106.131 1.00 170.87 ? 171 GLU D CA  1 
ATOM   7887  C C   . GLU D 2 171 ? -7.130  -26.190 -106.531 1.00 172.10 ? 171 GLU D C   1 
ATOM   7888  O O   . GLU D 2 171 ? -7.857  -26.981 -107.142 1.00 170.54 ? 171 GLU D O   1 
ATOM   7889  C CB  . GLU D 2 171 ? -7.739  -23.887 -107.344 1.00 163.53 ? 171 GLU D CB  1 
ATOM   7890  C CG  . GLU D 2 171 ? -8.550  -24.395 -108.537 1.00 153.43 ? 171 GLU D CG  1 
ATOM   7891  C CD  . GLU D 2 171 ? -9.942  -24.883 -108.162 1.00 155.09 ? 171 GLU D CD  1 
ATOM   7892  O OE1 . GLU D 2 171 ? -10.547 -24.334 -107.217 1.00 153.49 ? 171 GLU D OE1 1 
ATOM   7893  O OE2 . GLU D 2 171 ? -10.433 -25.823 -108.822 1.00 157.09 ? 171 GLU D OE2 1 
ATOM   7894  N N   . GLU D 2 172 ? -5.877  -26.497 -106.183 1.00 176.42 ? 172 GLU D N   1 
ATOM   7895  C CA  . GLU D 2 172 ? -5.382  -27.856 -106.380 1.00 179.90 ? 172 GLU D CA  1 
ATOM   7896  C C   . GLU D 2 172 ? -6.174  -28.845 -105.534 1.00 178.78 ? 172 GLU D C   1 
ATOM   7897  O O   . GLU D 2 172 ? -6.429  -29.977 -105.961 1.00 173.23 ? 172 GLU D O   1 
ATOM   7898  C CB  . GLU D 2 172 ? -3.890  -27.942 -106.047 1.00 180.19 ? 172 GLU D CB  1 
ATOM   7899  C CG  . GLU D 2 172 ? -2.980  -27.111 -106.943 1.00 183.63 ? 172 GLU D CG  1 
ATOM   7900  C CD  . GLU D 2 172 ? -3.157  -27.411 -108.420 1.00 185.54 ? 172 GLU D CD  1 
ATOM   7901  O OE1 . GLU D 2 172 ? -3.366  -28.590 -108.773 1.00 193.71 ? 172 GLU D OE1 1 
ATOM   7902  O OE2 . GLU D 2 172 ? -3.087  -26.461 -109.229 1.00 182.06 ? 172 GLU D OE2 1 
ATOM   7903  N N   . ILE D 2 173 ? -6.572  -28.432 -104.332 1.00 182.10 ? 173 ILE D N   1 
ATOM   7904  C CA  . ILE D 2 173 ? -7.406  -29.256 -103.456 1.00 174.84 ? 173 ILE D CA  1 
ATOM   7905  C C   . ILE D 2 173 ? -8.853  -28.970 -103.850 1.00 165.08 ? 173 ILE D C   1 
ATOM   7906  O O   . ILE D 2 173 ? -9.508  -28.081 -103.304 1.00 155.99 ? 173 ILE D O   1 
ATOM   7907  C CB  . ILE D 2 173 ? -7.138  -28.976 -101.980 1.00 168.83 ? 173 ILE D CB  1 
ATOM   7908  C CG1 . ILE D 2 173 ? -5.637  -29.048 -101.685 1.00 162.36 ? 173 ILE D CG1 1 
ATOM   7909  C CG2 . ILE D 2 173 ? -7.902  -29.958 -101.104 1.00 161.57 ? 173 ILE D CG2 1 
ATOM   7910  C CD1 . ILE D 2 173 ? -5.022  -30.401 -101.959 1.00 160.68 ? 173 ILE D CD1 1 
ATOM   7911  N N   . SER D 2 174 ? -9.354  -29.732 -104.816 1.00 157.93 ? 174 SER D N   1 
ATOM   7912  C CA  . SER D 2 174 ? -10.730 -29.580 -105.278 1.00 149.67 ? 174 SER D CA  1 
ATOM   7913  C C   . SER D 2 174 ? -11.351 -30.933 -105.606 1.00 140.05 ? 174 SER D C   1 
ATOM   7914  O O   . SER D 2 174 ? -12.522 -31.176 -105.314 1.00 134.52 ? 174 SER D O   1 
ATOM   7915  C CB  . SER D 2 174 ? -10.790 -28.663 -106.503 1.00 151.61 ? 174 SER D CB  1 
ATOM   7916  O OG  . SER D 2 174 ? -10.438 -27.333 -106.165 1.00 154.37 ? 174 SER D OG  1 
ATOM   7917  N N   . GLY E 1 4   ? -11.342 -0.122  -107.398 1.00 147.37 ? 10  GLY I N   1 
ATOM   7918  C CA  . GLY E 1 4   ? -12.756 0.193   -107.481 1.00 149.39 ? 10  GLY I CA  1 
ATOM   7919  C C   . GLY E 1 4   ? -13.186 1.271   -106.505 1.00 154.92 ? 10  GLY I C   1 
ATOM   7920  O O   . GLY E 1 4   ? -12.396 2.145   -106.146 1.00 152.48 ? 10  GLY I O   1 
ATOM   7921  N N   . ASP E 1 5   ? -14.443 1.210   -106.076 1.00 158.82 ? 11  ASP I N   1 
ATOM   7922  C CA  . ASP E 1 5   ? -14.976 2.162   -105.114 1.00 159.43 ? 11  ASP I CA  1 
ATOM   7923  C C   . ASP E 1 5   ? -14.719 1.684   -103.691 1.00 160.89 ? 11  ASP I C   1 
ATOM   7924  O O   . ASP E 1 5   ? -14.594 0.484   -103.429 1.00 158.40 ? 11  ASP I O   1 
ATOM   7925  C CB  . ASP E 1 5   ? -16.473 2.380   -105.335 1.00 157.42 ? 11  ASP I CB  1 
ATOM   7926  C CG  . ASP E 1 5   ? -16.759 3.309   -106.497 1.00 157.65 ? 11  ASP I CG  1 
ATOM   7927  O OD1 . ASP E 1 5   ? -15.793 3.853   -107.074 1.00 153.81 ? 11  ASP I OD1 1 
ATOM   7928  O OD2 . ASP E 1 5   ? -17.946 3.498   -106.834 1.00 160.09 ? 11  ASP I OD2 1 
ATOM   7929  N N   . GLN E 1 6   ? -14.642 2.641   -102.770 1.00 162.97 ? 12  GLN I N   1 
ATOM   7930  C CA  . GLN E 1 6   ? -14.216 2.380   -101.405 1.00 159.05 ? 12  GLN I CA  1 
ATOM   7931  C C   . GLN E 1 6   ? -15.195 3.004   -100.421 1.00 157.28 ? 12  GLN I C   1 
ATOM   7932  O O   . GLN E 1 6   ? -15.641 4.140   -100.610 1.00 152.09 ? 12  GLN I O   1 
ATOM   7933  C CB  . GLN E 1 6   ? -12.801 2.930   -101.174 1.00 156.95 ? 12  GLN I CB  1 
ATOM   7934  C CG  . GLN E 1 6   ? -12.127 2.465   -99.899  1.00 156.05 ? 12  GLN I CG  1 
ATOM   7935  C CD  . GLN E 1 6   ? -10.639 2.764   -99.898  1.00 146.80 ? 12  GLN I CD  1 
ATOM   7936  O OE1 . GLN E 1 6   ? -9.943  2.503   -100.880 1.00 143.26 ? 12  GLN I OE1 1 
ATOM   7937  N NE2 . GLN E 1 6   ? -10.146 3.322   -98.799  1.00 138.48 ? 12  GLN I NE2 1 
ATOM   7938  N N   . ILE E 1 7   ? -15.529 2.252   -99.373  1.00 158.34 ? 13  ILE I N   1 
ATOM   7939  C CA  . ILE E 1 7   ? -16.367 2.731   -98.281  1.00 155.78 ? 13  ILE I CA  1 
ATOM   7940  C C   . ILE E 1 7   ? -15.647 2.437   -96.972  1.00 152.37 ? 13  ILE I C   1 
ATOM   7941  O O   . ILE E 1 7   ? -14.979 1.406   -96.838  1.00 146.47 ? 13  ILE I O   1 
ATOM   7942  C CB  . ILE E 1 7   ? -17.774 2.090   -98.303  1.00 153.77 ? 13  ILE I CB  1 
ATOM   7943  C CG1 . ILE E 1 7   ? -18.680 2.732   -97.250  1.00 146.65 ? 13  ILE I CG1 1 
ATOM   7944  C CG2 . ILE E 1 7   ? -17.696 0.589   -98.088  1.00 146.43 ? 13  ILE I CG2 1 
ATOM   7945  C CD1 . ILE E 1 7   ? -18.904 4.212   -97.455  1.00 141.38 ? 13  ILE I CD1 1 
ATOM   7946  N N   . CYS E 1 8   ? -15.764 3.354   -96.013  1.00 149.03 ? 14  CYS I N   1 
ATOM   7947  C CA  . CYS E 1 8   ? -15.017 3.272   -94.767  1.00 141.60 ? 14  CYS I CA  1 
ATOM   7948  C C   . CYS E 1 8   ? -15.945 3.474   -93.578  1.00 139.50 ? 14  CYS I C   1 
ATOM   7949  O O   . CYS E 1 8   ? -16.990 4.121   -93.685  1.00 133.46 ? 14  CYS I O   1 
ATOM   7950  C CB  . CYS E 1 8   ? -13.891 4.314   -94.725  1.00 142.08 ? 14  CYS I CB  1 
ATOM   7951  S SG  . CYS E 1 8   ? -12.859 4.356   -96.208  1.00 139.35 ? 14  CYS I SG  1 
ATOM   7952  N N   . ILE E 1 9   ? -15.547 2.907   -92.441  1.00 139.84 ? 15  ILE I N   1 
ATOM   7953  C CA  . ILE E 1 9   ? -16.256 3.059   -91.176  1.00 137.01 ? 15  ILE I CA  1 
ATOM   7954  C C   . ILE E 1 9   ? -15.321 3.760   -90.201  1.00 137.31 ? 15  ILE I C   1 
ATOM   7955  O O   . ILE E 1 9   ? -14.154 3.375   -90.068  1.00 140.51 ? 15  ILE I O   1 
ATOM   7956  C CB  . ILE E 1 9   ? -16.716 1.703   -90.611  1.00 128.83 ? 15  ILE I CB  1 
ATOM   7957  C CG1 . ILE E 1 9   ? -17.372 0.859   -91.705  1.00 130.37 ? 15  ILE I CG1 1 
ATOM   7958  C CG2 . ILE E 1 9   ? -17.681 1.910   -89.454  1.00 125.10 ? 15  ILE I CG2 1 
ATOM   7959  C CD1 . ILE E 1 9   ? -18.629 1.469   -92.277  1.00 127.50 ? 15  ILE I CD1 1 
ATOM   7960  N N   . GLY E 1 10  ? -15.827 4.793   -89.530  1.00 134.88 ? 16  GLY I N   1 
ATOM   7961  C CA  . GLY E 1 10  ? -15.004 5.538   -88.594  1.00 135.55 ? 16  GLY I CA  1 
ATOM   7962  C C   . GLY E 1 10  ? -15.852 6.253   -87.567  1.00 134.79 ? 16  GLY I C   1 
ATOM   7963  O O   . GLY E 1 10  ? -17.081 6.295   -87.659  1.00 133.56 ? 16  GLY I O   1 
ATOM   7964  N N   . TYR E 1 11  ? -15.170 6.825   -86.582  1.00 129.63 ? 17  TYR I N   1 
ATOM   7965  C CA  . TYR E 1 11  ? -15.813 7.511   -85.470  1.00 118.64 ? 17  TYR I CA  1 
ATOM   7966  C C   . TYR E 1 11  ? -15.356 8.967   -85.410  1.00 121.72 ? 17  TYR I C   1 
ATOM   7967  O O   . TYR E 1 11  ? -14.539 9.426   -86.212  1.00 124.65 ? 17  TYR I O   1 
ATOM   7968  C CB  . TYR E 1 11  ? -15.535 6.789   -84.148  1.00 120.96 ? 17  TYR I CB  1 
ATOM   7969  C CG  . TYR E 1 11  ? -14.075 6.491   -83.888  1.00 124.09 ? 17  TYR I CG  1 
ATOM   7970  C CD1 . TYR E 1 11  ? -13.242 7.444   -83.315  1.00 121.32 ? 17  TYR I CD1 1 
ATOM   7971  C CD2 . TYR E 1 11  ? -13.534 5.251   -84.201  1.00 128.79 ? 17  TYR I CD2 1 
ATOM   7972  C CE1 . TYR E 1 11  ? -11.910 7.173   -83.071  1.00 123.87 ? 17  TYR I CE1 1 
ATOM   7973  C CE2 . TYR E 1 11  ? -12.203 4.971   -83.960  1.00 129.42 ? 17  TYR I CE2 1 
ATOM   7974  C CZ  . TYR E 1 11  ? -11.396 5.936   -83.396  1.00 125.26 ? 17  TYR I CZ  1 
ATOM   7975  O OH  . TYR E 1 11  ? -10.070 5.661   -83.154  1.00 133.63 ? 17  TYR I OH  1 
ATOM   7976  N N   . HIS E 1 12  ? -15.899 9.689   -84.433  1.00 120.62 ? 18  HIS I N   1 
ATOM   7977  C CA  . HIS E 1 12  ? -15.688 11.124  -84.309  1.00 106.35 ? 18  HIS I CA  1 
ATOM   7978  C C   . HIS E 1 12  ? -14.378 11.432  -83.592  1.00 105.92 ? 18  HIS I C   1 
ATOM   7979  O O   . HIS E 1 12  ? -13.866 10.629  -82.806  1.00 111.00 ? 18  HIS I O   1 
ATOM   7980  C CB  . HIS E 1 12  ? -16.860 11.759  -83.556  1.00 109.77 ? 18  HIS I CB  1 
ATOM   7981  C CG  . HIS E 1 12  ? -16.747 13.242  -83.380  1.00 112.79 ? 18  HIS I CG  1 
ATOM   7982  N ND1 . HIS E 1 12  ? -17.236 14.141  -84.302  1.00 117.24 ? 18  HIS I ND1 1 
ATOM   7983  C CD2 . HIS E 1 12  ? -16.211 13.982  -82.380  1.00 114.32 ? 18  HIS I CD2 1 
ATOM   7984  C CE1 . HIS E 1 12  ? -17.002 15.372  -83.881  1.00 119.83 ? 18  HIS I CE1 1 
ATOM   7985  N NE2 . HIS E 1 12  ? -16.380 15.303  -82.718  1.00 116.90 ? 18  HIS I NE2 1 
ATOM   7986  N N   . ALA E 1 13  ? -13.832 12.612  -83.884  1.00 111.25 ? 19  ALA I N   1 
ATOM   7987  C CA  . ALA E 1 13  ? -12.689 13.154  -83.165  1.00 104.46 ? 19  ALA I CA  1 
ATOM   7988  C C   . ALA E 1 13  ? -12.758 14.673  -83.241  1.00 108.99 ? 19  ALA I C   1 
ATOM   7989  O O   . ALA E 1 13  ? -13.402 15.237  -84.129  1.00 114.27 ? 19  ALA I O   1 
ATOM   7990  C CB  . ALA E 1 13  ? -11.362 12.638  -83.732  1.00 98.55  ? 19  ALA I CB  1 
ATOM   7991  N N   . ASN E 1 14  ? -12.091 15.333  -82.298  1.00 103.50 ? 20  ASN I N   1 
ATOM   7992  C CA  . ASN E 1 14  ? -12.113 16.789  -82.243  1.00 105.99 ? 20  ASN I CA  1 
ATOM   7993  C C   . ASN E 1 14  ? -10.904 17.276  -81.458  1.00 112.38 ? 20  ASN I C   1 
ATOM   7994  O O   . ASN E 1 14  ? -10.219 16.501  -80.786  1.00 115.46 ? 20  ASN I O   1 
ATOM   7995  C CB  . ASN E 1 14  ? -13.420 17.306  -81.626  1.00 106.73 ? 20  ASN I CB  1 
ATOM   7996  C CG  . ASN E 1 14  ? -13.564 16.941  -80.156  1.00 115.59 ? 20  ASN I CG  1 
ATOM   7997  O OD1 . ASN E 1 14  ? -12.849 16.082  -79.639  1.00 105.14 ? 20  ASN I OD1 1 
ATOM   7998  N ND2 . ASN E 1 14  ? -14.502 17.592  -79.477  1.00 103.80 ? 20  ASN I ND2 1 
ATOM   7999  N N   . ASN E 1 15  ? -10.647 18.579  -81.554  1.00 112.72 ? 21  ASN I N   1 
ATOM   8000  C CA  . ASN E 1 15  ? -9.572  19.189  -80.783  1.00 119.45 ? 21  ASN I CA  1 
ATOM   8001  C C   . ASN E 1 15  ? -9.984  19.289  -79.320  1.00 118.82 ? 21  ASN I C   1 
ATOM   8002  O O   . ASN E 1 15  ? -10.621 20.265  -78.914  1.00 124.25 ? 21  ASN I O   1 
ATOM   8003  C CB  . ASN E 1 15  ? -9.220  20.570  -81.340  1.00 132.95 ? 21  ASN I CB  1 
ATOM   8004  C CG  . ASN E 1 15  ? -8.795  20.520  -82.796  1.00 138.71 ? 21  ASN I CG  1 
ATOM   8005  O OD1 . ASN E 1 15  ? -7.666  20.145  -83.114  1.00 132.89 ? 21  ASN I OD1 1 
ATOM   8006  N ND2 . ASN E 1 15  ? -9.700  20.904  -83.690  1.00 131.77 ? 21  ASN I ND2 1 
ATOM   8007  N N   . SER E 1 16  ? -9.626  18.282  -78.525  1.00 120.98 ? 22  SER I N   1 
ATOM   8008  C CA  . SER E 1 16  ? -10.053 18.215  -77.131  1.00 119.57 ? 22  SER I CA  1 
ATOM   8009  C C   . SER E 1 16  ? -8.996  17.482  -76.321  1.00 119.78 ? 22  SER I C   1 
ATOM   8010  O O   . SER E 1 16  ? -8.646  16.343  -76.644  1.00 114.46 ? 22  SER I O   1 
ATOM   8011  C CB  . SER E 1 16  ? -11.408 17.513  -77.006  1.00 119.55 ? 22  SER I CB  1 
ATOM   8012  O OG  . SER E 1 16  ? -11.732 17.267  -75.649  1.00 111.99 ? 22  SER I OG  1 
ATOM   8013  N N   . THR E 1 17  ? -8.498  18.134  -75.272  1.00 123.54 ? 23  THR I N   1 
ATOM   8014  C CA  . THR E 1 17  ? -7.531  17.543  -74.359  1.00 119.75 ? 23  THR I CA  1 
ATOM   8015  C C   . THR E 1 17  ? -8.177  17.025  -73.080  1.00 118.76 ? 23  THR I C   1 
ATOM   8016  O O   . THR E 1 17  ? -7.464  16.716  -72.120  1.00 109.92 ? 23  THR I O   1 
ATOM   8017  C CB  . THR E 1 17  ? -6.438  18.558  -74.016  1.00 117.18 ? 23  THR I CB  1 
ATOM   8018  O OG1 . THR E 1 17  ? -7.039  19.816  -73.682  1.00 117.87 ? 23  THR I OG1 1 
ATOM   8019  C CG2 . THR E 1 17  ? -5.493  18.746  -75.194  1.00 112.90 ? 23  THR I CG2 1 
ATOM   8020  N N   . GLU E 1 18  ? -9.506  16.929  -73.047  1.00 118.24 ? 24  GLU I N   1 
ATOM   8021  C CA  . GLU E 1 18  ? -10.203 16.473  -71.852  1.00 108.32 ? 24  GLU I CA  1 
ATOM   8022  C C   . GLU E 1 18  ? -9.789  15.049  -71.502  1.00 105.42 ? 24  GLU I C   1 
ATOM   8023  O O   . GLU E 1 18  ? -9.625  14.198  -72.380  1.00 104.71 ? 24  GLU I O   1 
ATOM   8024  C CB  . GLU E 1 18  ? -11.716 16.547  -72.068  1.00 107.90 ? 24  GLU I CB  1 
ATOM   8025  C CG  . GLU E 1 18  ? -12.524 16.720  -70.793  1.00 118.55 ? 24  GLU I CG  1 
ATOM   8026  C CD  . GLU E 1 18  ? -12.412 18.119  -70.215  1.00 128.26 ? 24  GLU I CD  1 
ATOM   8027  O OE1 . GLU E 1 18  ? -11.980 19.036  -70.947  1.00 124.62 ? 24  GLU I OE1 1 
ATOM   8028  O OE2 . GLU E 1 18  ? -12.758 18.303  -69.029  1.00 128.21 ? 24  GLU I OE2 1 
ATOM   8029  N N   . GLN E 1 19  ? -9.624  14.790  -70.206  1.00 101.32 ? 25  GLN I N   1 
ATOM   8030  C CA  . GLN E 1 19  ? -9.095  13.525  -69.716  1.00 99.94  ? 25  GLN I CA  1 
ATOM   8031  C C   . GLN E 1 19  ? -10.088 12.843  -68.786  1.00 96.89  ? 25  GLN I C   1 
ATOM   8032  O O   . GLN E 1 19  ? -10.794 13.504  -68.018  1.00 99.31  ? 25  GLN I O   1 
ATOM   8033  C CB  . GLN E 1 19  ? -7.773  13.727  -68.970  1.00 98.54  ? 25  GLN I CB  1 
ATOM   8034  C CG  . GLN E 1 19  ? -6.548  13.813  -69.857  1.00 91.78  ? 25  GLN I CG  1 
ATOM   8035  C CD  . GLN E 1 19  ? -5.291  13.369  -69.135  1.00 103.04 ? 25  GLN I CD  1 
ATOM   8036  O OE1 . GLN E 1 19  ? -4.926  12.196  -69.173  1.00 106.18 ? 25  GLN I OE1 1 
ATOM   8037  N NE2 . GLN E 1 19  ? -4.627  14.304  -68.465  1.00 97.74  ? 25  GLN I NE2 1 
ATOM   8038  N N   . VAL E 1 20  ? -10.135 11.511  -68.865  1.00 79.08  ? 26  VAL I N   1 
ATOM   8039  C CA  . VAL E 1 20  ? -10.847 10.676  -67.908  1.00 83.88  ? 26  VAL I CA  1 
ATOM   8040  C C   . VAL E 1 20  ? -9.945  9.507   -67.537  1.00 89.08  ? 26  VAL I C   1 
ATOM   8041  O O   . VAL E 1 20  ? -8.931  9.242   -68.185  1.00 89.92  ? 26  VAL I O   1 
ATOM   8042  C CB  . VAL E 1 20  ? -12.197 10.153  -68.445  1.00 84.14  ? 26  VAL I CB  1 
ATOM   8043  C CG1 . VAL E 1 20  ? -13.045 11.288  -69.006  1.00 92.86  ? 26  VAL I CG1 1 
ATOM   8044  C CG2 . VAL E 1 20  ? -11.967 9.060   -69.480  1.00 86.62  ? 26  VAL I CG2 1 
ATOM   8045  N N   . ASP E 1 21  ? -10.330 8.804   -66.477  1.00 87.80  ? 27  ASP I N   1 
ATOM   8046  C CA  . ASP E 1 21  ? -9.643  7.601   -66.037  1.00 85.05  ? 27  ASP I CA  1 
ATOM   8047  C C   . ASP E 1 21  ? -10.619 6.433   -66.017  1.00 81.43  ? 27  ASP I C   1 
ATOM   8048  O O   . ASP E 1 21  ? -11.824 6.612   -65.816  1.00 83.54  ? 27  ASP I O   1 
ATOM   8049  C CB  . ASP E 1 21  ? -9.021  7.785   -64.646  1.00 83.10  ? 27  ASP I CB  1 
ATOM   8050  C CG  . ASP E 1 21  ? -7.778  8.654   -64.672  1.00 104.97 ? 27  ASP I CG  1 
ATOM   8051  O OD1 . ASP E 1 21  ? -7.867  9.813   -65.130  1.00 106.85 ? 27  ASP I OD1 1 
ATOM   8052  O OD2 . ASP E 1 21  ? -6.712  8.178   -64.228  1.00 112.52 ? 27  ASP I OD2 1 
ATOM   8053  N N   . THR E 1 22  ? -10.090 5.233   -66.244  1.00 70.01  ? 28  THR I N   1 
ATOM   8054  C CA  . THR E 1 22  ? -10.868 4.006   -66.177  1.00 86.79  ? 28  THR I CA  1 
ATOM   8055  C C   . THR E 1 22  ? -10.202 3.052   -65.197  1.00 82.09  ? 28  THR I C   1 
ATOM   8056  O O   . THR E 1 22  ? -9.088  3.290   -64.721  1.00 80.27  ? 28  THR I O   1 
ATOM   8057  C CB  . THR E 1 22  ? -11.012 3.333   -67.553  1.00 87.22  ? 28  THR I CB  1 
ATOM   8058  O OG1 . THR E 1 22  ? -9.900  2.459   -67.782  1.00 81.50  ? 28  THR I OG1 1 
ATOM   8059  C CG2 . THR E 1 22  ? -11.068 4.372   -68.663  1.00 82.37  ? 28  THR I CG2 1 
ATOM   8060  N N   . ILE E 1 23  ? -10.902 1.954   -64.901  1.00 72.73  ? 29  ILE I N   1 
ATOM   8061  C CA  . ILE E 1 23  ? -10.396 0.984   -63.935  1.00 81.43  ? 29  ILE I CA  1 
ATOM   8062  C C   . ILE E 1 23  ? -9.111  0.333   -64.435  1.00 85.90  ? 29  ILE I C   1 
ATOM   8063  O O   . ILE E 1 23  ? -8.225  -0.002  -63.638  1.00 79.81  ? 29  ILE I O   1 
ATOM   8064  C CB  . ILE E 1 23  ? -11.488 -0.060  -63.610  1.00 86.83  ? 29  ILE I CB  1 
ATOM   8065  C CG1 . ILE E 1 23  ? -10.990 -1.064  -62.570  1.00 81.22  ? 29  ILE I CG1 1 
ATOM   8066  C CG2 . ILE E 1 23  ? -11.944 -0.780  -64.865  1.00 93.93  ? 29  ILE I CG2 1 
ATOM   8067  C CD1 . ILE E 1 23  ? -10.466 -0.420  -61.311  1.00 84.30  ? 29  ILE I CD1 1 
ATOM   8068  N N   . MET E 1 24  ? -8.977  0.150   -65.750  1.00 99.69  ? 30  MET I N   1 
ATOM   8069  C CA  . MET E 1 24  ? -7.808  -0.512  -66.312  1.00 94.85  ? 30  MET I CA  1 
ATOM   8070  C C   . MET E 1 24  ? -6.819  0.426   -66.984  1.00 88.75  ? 30  MET I C   1 
ATOM   8071  O O   . MET E 1 24  ? -5.645  0.064   -67.108  1.00 90.46  ? 30  MET I O   1 
ATOM   8072  C CB  . MET E 1 24  ? -8.238  -1.585  -67.323  1.00 82.75  ? 30  MET I CB  1 
ATOM   8073  C CG  . MET E 1 24  ? -8.268  -2.983  -66.738  1.00 88.56  ? 30  MET I CG  1 
ATOM   8074  S SD  . MET E 1 24  ? -9.398  -4.077  -67.608  1.00 118.18 ? 30  MET I SD  1 
ATOM   8075  C CE  . MET E 1 24  ? -10.927 -3.166  -67.427  1.00 110.31 ? 30  MET I CE  1 
ATOM   8076  N N   . GLU E 1 25  ? -7.247  1.610   -67.415  1.00 87.43  ? 31  GLU I N   1 
ATOM   8077  C CA  . GLU E 1 25  ? -6.375  2.531   -68.132  1.00 92.69  ? 31  GLU I CA  1 
ATOM   8078  C C   . GLU E 1 25  ? -6.368  3.886   -67.443  1.00 96.90  ? 31  GLU I C   1 
ATOM   8079  O O   . GLU E 1 25  ? -7.430  4.426   -67.116  1.00 98.50  ? 31  GLU I O   1 
ATOM   8080  C CB  . GLU E 1 25  ? -6.816  2.693   -69.589  1.00 96.52  ? 31  GLU I CB  1 
ATOM   8081  C CG  . GLU E 1 25  ? -6.931  1.392   -70.356  1.00 97.15  ? 31  GLU I CG  1 
ATOM   8082  C CD  . GLU E 1 25  ? -7.278  1.613   -71.812  1.00 107.03 ? 31  GLU I CD  1 
ATOM   8083  O OE1 . GLU E 1 25  ? -6.783  2.599   -72.398  1.00 97.82  ? 31  GLU I OE1 1 
ATOM   8084  O OE2 . GLU E 1 25  ? -8.054  0.807   -72.369  1.00 102.36 ? 31  GLU I OE2 1 
ATOM   8085  N N   . LYS E 1 26  ? -5.174  4.427   -67.228  1.00 95.82  ? 32  LYS I N   1 
ATOM   8086  C CA  . LYS E 1 26  ? -5.006  5.775   -66.713  1.00 99.61  ? 32  LYS I CA  1 
ATOM   8087  C C   . LYS E 1 26  ? -4.921  6.767   -67.869  1.00 99.83  ? 32  LYS I C   1 
ATOM   8088  O O   . LYS E 1 26  ? -4.659  6.395   -69.015  1.00 99.71  ? 32  LYS I O   1 
ATOM   8089  C CB  . LYS E 1 26  ? -3.748  5.866   -65.841  1.00 97.30  ? 32  LYS I CB  1 
ATOM   8090  C CG  . LYS E 1 26  ? -2.468  6.291   -66.571  1.00 106.19 ? 32  LYS I CG  1 
ATOM   8091  C CD  . LYS E 1 26  ? -1.980  5.281   -67.616  1.00 97.55  ? 32  LYS I CD  1 
ATOM   8092  C CE  . LYS E 1 26  ? -0.690  5.768   -68.273  1.00 95.72  ? 32  LYS I CE  1 
ATOM   8093  N NZ  . LYS E 1 26  ? -0.459  5.158   -69.617  1.00 106.43 ? 32  LYS I NZ  1 
ATOM   8094  N N   . ASN E 1 27  ? -5.172  8.038   -67.553  1.00 99.70  ? 33  ASN I N   1 
ATOM   8095  C CA  . ASN E 1 27  ? -4.840  9.171   -68.420  1.00 95.05  ? 33  ASN I CA  1 
ATOM   8096  C C   . ASN E 1 27  ? -5.300  8.941   -69.864  1.00 93.08  ? 33  ASN I C   1 
ATOM   8097  O O   . ASN E 1 27  ? -4.503  8.831   -70.794  1.00 104.27 ? 33  ASN I O   1 
ATOM   8098  C CB  . ASN E 1 27  ? -3.336  9.456   -68.366  1.00 91.32  ? 33  ASN I CB  1 
ATOM   8099  C CG  . ASN E 1 27  ? -2.944  10.311  -67.177  1.00 101.95 ? 33  ASN I CG  1 
ATOM   8100  O OD1 . ASN E 1 27  ? -3.785  10.681  -66.359  1.00 104.81 ? 33  ASN I OD1 1 
ATOM   8101  N ND2 . ASN E 1 27  ? -1.657  10.628  -67.075  1.00 108.76 ? 33  ASN I ND2 1 
ATOM   8102  N N   . VAL E 1 28  ? -6.618  8.862   -70.025  1.00 90.02  ? 34  VAL I N   1 
ATOM   8103  C CA  . VAL E 1 28  ? -7.245  8.626   -71.321  1.00 84.30  ? 34  VAL I CA  1 
ATOM   8104  C C   . VAL E 1 28  ? -7.916  9.913   -71.783  1.00 85.71  ? 34  VAL I C   1 
ATOM   8105  O O   . VAL E 1 28  ? -8.729  10.494  -71.055  1.00 96.91  ? 34  VAL I O   1 
ATOM   8106  C CB  . VAL E 1 28  ? -8.258  7.470   -71.256  1.00 86.67  ? 34  VAL I CB  1 
ATOM   8107  C CG1 . VAL E 1 28  ? -9.170  7.495   -72.472  1.00 79.13  ? 34  VAL I CG1 1 
ATOM   8108  C CG2 . VAL E 1 28  ? -7.531  6.137   -71.163  1.00 85.06  ? 34  VAL I CG2 1 
ATOM   8109  N N   . THR E 1 29  ? -7.576  10.352  -72.994  1.00 94.79  ? 35  THR I N   1 
ATOM   8110  C CA  . THR E 1 29  ? -8.168  11.543  -73.587  1.00 88.20  ? 35  THR I CA  1 
ATOM   8111  C C   . THR E 1 29  ? -9.430  11.169  -74.354  1.00 89.08  ? 35  THR I C   1 
ATOM   8112  O O   . THR E 1 29  ? -9.448  10.186  -75.101  1.00 80.83  ? 35  THR I O   1 
ATOM   8113  C CB  . THR E 1 29  ? -7.172  12.233  -74.523  1.00 90.61  ? 35  THR I CB  1 
ATOM   8114  O OG1 . THR E 1 29  ? -5.977  12.559  -73.800  1.00 90.23  ? 35  THR I OG1 1 
ATOM   8115  C CG2 . THR E 1 29  ? -7.771  13.508  -75.102  1.00 89.28  ? 35  THR I CG2 1 
ATOM   8116  N N   . VAL E 1 30  ? -10.489 11.957  -74.162  1.00 88.73  ? 36  VAL I N   1 
ATOM   8117  C CA  . VAL E 1 30  ? -11.781 11.701  -74.781  1.00 93.38  ? 36  VAL I CA  1 
ATOM   8118  C C   . VAL E 1 30  ? -12.251 12.962  -75.496  1.00 93.93  ? 36  VAL I C   1 
ATOM   8119  O O   . VAL E 1 30  ? -11.691 14.047  -75.336  1.00 89.63  ? 36  VAL I O   1 
ATOM   8120  C CB  . VAL E 1 30  ? -12.846 11.239  -73.764  1.00 91.52  ? 36  VAL I CB  1 
ATOM   8121  C CG1 . VAL E 1 30  ? -12.274 10.193  -72.830  1.00 90.93  ? 36  VAL I CG1 1 
ATOM   8122  C CG2 . VAL E 1 30  ? -13.397 12.426  -72.984  1.00 95.07  ? 36  VAL I CG2 1 
ATOM   8123  N N   . THR E 1 31  ? -13.305 12.795  -76.297  1.00 93.11  ? 37  THR I N   1 
ATOM   8124  C CA  . THR E 1 31  ? -13.899 13.916  -77.017  1.00 99.33  ? 37  THR I CA  1 
ATOM   8125  C C   . THR E 1 31  ? -14.748 14.781  -76.090  1.00 107.44 ? 37  THR I C   1 
ATOM   8126  O O   . THR E 1 31  ? -14.520 15.989  -75.968  1.00 110.81 ? 37  THR I O   1 
ATOM   8127  C CB  . THR E 1 31  ? -14.738 13.397  -78.190  1.00 103.24 ? 37  THR I CB  1 
ATOM   8128  O OG1 . THR E 1 31  ? -15.415 12.196  -77.800  1.00 97.06  ? 37  THR I OG1 1 
ATOM   8129  C CG2 . THR E 1 31  ? -13.859 13.105  -79.395  1.00 99.75  ? 37  THR I CG2 1 
ATOM   8130  N N   . HIS E 1 32  ? -15.733 14.176  -75.428  1.00 101.20 ? 38  HIS I N   1 
ATOM   8131  C CA  . HIS E 1 32  ? -16.630 14.885  -74.527  1.00 97.18  ? 38  HIS I CA  1 
ATOM   8132  C C   . HIS E 1 32  ? -16.668 14.173  -73.182  1.00 104.10 ? 38  HIS I C   1 
ATOM   8133  O O   . HIS E 1 32  ? -16.727 12.941  -73.125  1.00 99.07  ? 38  HIS I O   1 
ATOM   8134  C CB  . HIS E 1 32  ? -18.050 14.981  -75.110  1.00 98.36  ? 38  HIS I CB  1 
ATOM   8135  C CG  . HIS E 1 32  ? -18.098 15.521  -76.506  1.00 111.09 ? 38  HIS I CG  1 
ATOM   8136  N ND1 . HIS E 1 32  ? -17.639 14.810  -77.595  1.00 113.96 ? 38  HIS I ND1 1 
ATOM   8137  C CD2 . HIS E 1 32  ? -18.561 16.696  -76.994  1.00 107.25 ? 38  HIS I CD2 1 
ATOM   8138  C CE1 . HIS E 1 32  ? -17.809 15.527  -78.691  1.00 110.52 ? 38  HIS I CE1 1 
ATOM   8139  N NE2 . HIS E 1 32  ? -18.368 16.676  -78.354  1.00 109.50 ? 38  HIS I NE2 1 
ATOM   8140  N N   . ALA E 1 33  ? -16.641 14.953  -72.102  1.00 100.03 ? 39  ALA I N   1 
ATOM   8141  C CA  . ALA E 1 33  ? -16.665 14.397  -70.757  1.00 92.51  ? 39  ALA I CA  1 
ATOM   8142  C C   . ALA E 1 33  ? -17.421 15.343  -69.836  1.00 95.53  ? 39  ALA I C   1 
ATOM   8143  O O   . ALA E 1 33  ? -17.569 16.535  -70.121  1.00 75.84  ? 39  ALA I O   1 
ATOM   8144  C CB  . ALA E 1 33  ? -15.250 14.145  -70.223  1.00 72.51  ? 39  ALA I CB  1 
ATOM   8145  N N   . GLN E 1 34  ? -17.900 14.794  -68.720  1.00 92.72  ? 40  GLN I N   1 
ATOM   8146  C CA  . GLN E 1 34  ? -18.681 15.554  -67.755  1.00 99.18  ? 40  GLN I CA  1 
ATOM   8147  C C   . GLN E 1 34  ? -18.204 15.238  -66.345  1.00 91.77  ? 40  GLN I C   1 
ATOM   8148  O O   . GLN E 1 34  ? -17.944 14.077  -66.013  1.00 85.99  ? 40  GLN I O   1 
ATOM   8149  C CB  . GLN E 1 34  ? -20.178 15.245  -67.893  1.00 93.16  ? 40  GLN I CB  1 
ATOM   8150  C CG  . GLN E 1 34  ? -21.095 16.309  -67.312  1.00 83.69  ? 40  GLN I CG  1 
ATOM   8151  C CD  . GLN E 1 34  ? -22.552 16.068  -67.659  1.00 105.81 ? 40  GLN I CD  1 
ATOM   8152  O OE1 . GLN E 1 34  ? -23.435 16.816  -67.239  1.00 102.98 ? 40  GLN I OE1 1 
ATOM   8153  N NE2 . GLN E 1 34  ? -22.809 15.019  -68.434  1.00 98.79  ? 40  GLN I NE2 1 
ATOM   8154  N N   . ASP E 1 35  ? -18.095 16.276  -65.520  1.00 86.24  ? 41  ASP I N   1 
ATOM   8155  C CA  . ASP E 1 35  ? -17.644 16.150  -64.141  1.00 91.40  ? 41  ASP I CA  1 
ATOM   8156  C C   . ASP E 1 35  ? -18.852 16.183  -63.213  1.00 83.95  ? 41  ASP I C   1 
ATOM   8157  O O   . ASP E 1 35  ? -19.702 17.073  -63.324  1.00 84.00  ? 41  ASP I O   1 
ATOM   8158  C CB  . ASP E 1 35  ? -16.666 17.275  -63.786  1.00 99.55  ? 41  ASP I CB  1 
ATOM   8159  C CG  . ASP E 1 35  ? -15.947 17.040  -62.467  1.00 94.70  ? 41  ASP I CG  1 
ATOM   8160  O OD1 . ASP E 1 35  ? -16.147 15.974  -61.850  1.00 94.86  ? 41  ASP I OD1 1 
ATOM   8161  O OD2 . ASP E 1 35  ? -15.174 17.927  -62.045  1.00 89.13  ? 41  ASP I OD2 1 
ATOM   8162  N N   . ILE E 1 36  ? -18.927 15.213  -62.306  1.00 91.51  ? 42  ILE I N   1 
ATOM   8163  C CA  . ILE E 1 36  ? -20.037 15.104  -61.369  1.00 87.15  ? 42  ILE I CA  1 
ATOM   8164  C C   . ILE E 1 36  ? -19.623 15.538  -59.963  1.00 90.00  ? 42  ILE I C   1 
ATOM   8165  O O   . ILE E 1 36  ? -20.273 15.174  -58.984  1.00 88.80  ? 42  ILE I O   1 
ATOM   8166  C CB  . ILE E 1 36  ? -20.628 13.685  -61.363  1.00 70.74  ? 42  ILE I CB  1 
ATOM   8167  C CG1 . ILE E 1 36  ? -19.579 12.668  -60.908  1.00 75.01  ? 42  ILE I CG1 1 
ATOM   8168  C CG2 . ILE E 1 36  ? -21.157 13.326  -62.741  1.00 73.78  ? 42  ILE I CG2 1 
ATOM   8169  C CD1 . ILE E 1 36  ? -20.074 11.237  -60.914  1.00 78.35  ? 42  ILE I CD1 1 
ATOM   8170  N N   . LEU E 1 37  ? -18.548 16.313  -59.850  1.00 83.36  ? 43  LEU I N   1 
ATOM   8171  C CA  . LEU E 1 37  ? -18.058 16.811  -58.570  1.00 75.79  ? 43  LEU I CA  1 
ATOM   8172  C C   . LEU E 1 37  ? -18.241 18.323  -58.539  1.00 76.93  ? 43  LEU I C   1 
ATOM   8173  O O   . LEU E 1 37  ? -17.605 19.047  -59.313  1.00 79.54  ? 43  LEU I O   1 
ATOM   8174  C CB  . LEU E 1 37  ? -16.593 16.433  -58.362  1.00 65.62  ? 43  LEU I CB  1 
ATOM   8175  C CG  . LEU E 1 37  ? -15.997 16.858  -57.021  1.00 74.80  ? 43  LEU I CG  1 
ATOM   8176  C CD1 . LEU E 1 37  ? -16.626 16.064  -55.891  1.00 76.88  ? 43  LEU I CD1 1 
ATOM   8177  C CD2 . LEU E 1 37  ? -14.493 16.688  -57.023  1.00 75.69  ? 43  LEU I CD2 1 
ATOM   8178  N N   . GLU E 1 38  ? -19.106 18.799  -57.647  1.00 69.31  ? 44  GLU I N   1 
ATOM   8179  C CA  . GLU E 1 38  ? -19.322 20.231  -57.496  1.00 78.36  ? 44  GLU I CA  1 
ATOM   8180  C C   . GLU E 1 38  ? -18.202 20.838  -56.660  1.00 73.90  ? 44  GLU I C   1 
ATOM   8181  O O   . GLU E 1 38  ? -17.871 20.330  -55.585  1.00 65.74  ? 44  GLU I O   1 
ATOM   8182  C CB  . GLU E 1 38  ? -20.680 20.506  -56.852  1.00 77.54  ? 44  GLU I CB  1 
ATOM   8183  C CG  . GLU E 1 38  ? -20.980 21.985  -56.624  1.00 80.52  ? 44  GLU I CG  1 
ATOM   8184  C CD  . GLU E 1 38  ? -20.861 22.820  -57.890  1.00 88.41  ? 44  GLU I CD  1 
ATOM   8185  O OE1 . GLU E 1 38  ? -19.735 23.244  -58.229  1.00 90.50  ? 44  GLU I OE1 1 
ATOM   8186  O OE2 . GLU E 1 38  ? -21.895 23.054  -58.549  1.00 90.60  ? 44  GLU I OE2 1 
ATOM   8187  N N   . LYS E 1 39  ? -17.614 21.927  -57.162  1.00 72.16  ? 45  LYS I N   1 
ATOM   8188  C CA  . LYS E 1 39  ? -16.485 22.568  -56.501  1.00 67.88  ? 45  LYS I CA  1 
ATOM   8189  C C   . LYS E 1 39  ? -16.651 24.079  -56.389  1.00 62.08  ? 45  LYS I C   1 
ATOM   8190  O O   . LYS E 1 39  ? -15.718 24.759  -55.947  1.00 69.40  ? 45  LYS I O   1 
ATOM   8191  C CB  . LYS E 1 39  ? -15.178 22.247  -57.241  1.00 69.81  ? 45  LYS I CB  1 
ATOM   8192  C CG  . LYS E 1 39  ? -14.981 20.767  -57.555  1.00 75.33  ? 45  LYS I CG  1 
ATOM   8193  C CD  . LYS E 1 39  ? -13.572 20.467  -58.054  1.00 89.08  ? 45  LYS I CD  1 
ATOM   8194  C CE  . LYS E 1 39  ? -13.498 20.425  -59.573  1.00 74.91  ? 45  LYS I CE  1 
ATOM   8195  N NZ  . LYS E 1 39  ? -12.147 20.000  -60.036  1.00 92.16  ? 45  LYS I NZ  1 
ATOM   8196  N N   . THR E 1 40  ? -17.809 24.621  -56.762  1.00 62.31  ? 46  THR I N   1 
ATOM   8197  C CA  . THR E 1 40  ? -18.009 26.060  -56.858  1.00 73.50  ? 46  THR I CA  1 
ATOM   8198  C C   . THR E 1 40  ? -19.105 26.517  -55.905  1.00 78.02  ? 46  THR I C   1 
ATOM   8199  O O   . THR E 1 40  ? -20.133 25.847  -55.754  1.00 66.06  ? 46  THR I O   1 
ATOM   8200  C CB  . THR E 1 40  ? -18.371 26.474  -58.291  1.00 79.54  ? 46  THR I CB  1 
ATOM   8201  O OG1 . THR E 1 40  ? -19.711 26.062  -58.586  1.00 85.97  ? 46  THR I OG1 1 
ATOM   8202  C CG2 . THR E 1 40  ? -17.421 25.827  -59.290  1.00 67.85  ? 46  THR I CG2 1 
ATOM   8203  N N   . HIS E 1 41  ? -18.877 27.666  -55.269  1.00 79.97  ? 47  HIS I N   1 
ATOM   8204  C CA  . HIS E 1 41  ? -19.841 28.293  -54.377  1.00 71.43  ? 47  HIS I CA  1 
ATOM   8205  C C   . HIS E 1 41  ? -19.850 29.791  -54.654  1.00 66.79  ? 47  HIS I C   1 
ATOM   8206  O O   . HIS E 1 41  ? -18.966 30.321  -55.331  1.00 77.17  ? 47  HIS I O   1 
ATOM   8207  C CB  . HIS E 1 41  ? -19.511 28.005  -52.906  1.00 64.16  ? 47  HIS I CB  1 
ATOM   8208  C CG  . HIS E 1 41  ? -18.127 28.413  -52.507  1.00 52.69  ? 47  HIS I CG  1 
ATOM   8209  N ND1 . HIS E 1 41  ? -17.825 29.682  -52.062  1.00 58.98  ? 47  HIS I ND1 1 
ATOM   8210  C CD2 . HIS E 1 41  ? -16.963 27.721  -52.491  1.00 52.05  ? 47  HIS I CD2 1 
ATOM   8211  C CE1 . HIS E 1 41  ? -16.535 29.753  -51.786  1.00 64.51  ? 47  HIS I CE1 1 
ATOM   8212  N NE2 . HIS E 1 41  ? -15.989 28.577  -52.038  1.00 67.93  ? 47  HIS I NE2 1 
ATOM   8213  N N   . ASN E 1 42  ? -20.863 30.482  -54.125  1.00 70.48  ? 48  ASN I N   1 
ATOM   8214  C CA  . ASN E 1 42  ? -21.019 31.908  -54.392  1.00 64.36  ? 48  ASN I CA  1 
ATOM   8215  C C   . ASN E 1 42  ? -20.252 32.799  -53.421  1.00 72.98  ? 48  ASN I C   1 
ATOM   8216  O O   . ASN E 1 42  ? -20.214 34.017  -53.625  1.00 77.70  ? 48  ASN I O   1 
ATOM   8217  C CB  . ASN E 1 42  ? -22.507 32.301  -54.387  1.00 68.70  ? 48  ASN I CB  1 
ATOM   8218  C CG  . ASN E 1 42  ? -23.170 32.149  -53.020  1.00 75.89  ? 48  ASN I CG  1 
ATOM   8219  O OD1 . ASN E 1 42  ? -22.510 32.067  -51.984  1.00 83.61  ? 48  ASN I OD1 1 
ATOM   8220  N ND2 . ASN E 1 42  ? -24.498 32.124  -53.022  1.00 72.64  ? 48  ASN I ND2 1 
ATOM   8221  N N   . GLY E 1 43  ? -19.662 32.233  -52.370  1.00 76.22  ? 49  GLY I N   1 
ATOM   8222  C CA  . GLY E 1 43  ? -18.916 33.034  -51.419  1.00 71.15  ? 49  GLY I CA  1 
ATOM   8223  C C   . GLY E 1 43  ? -19.750 33.964  -50.567  1.00 73.77  ? 49  GLY I C   1 
ATOM   8224  O O   . GLY E 1 43  ? -19.226 34.964  -50.069  1.00 72.77  ? 49  GLY I O   1 
ATOM   8225  N N   . LYS E 1 44  ? -21.037 33.671  -50.388  1.00 66.84  ? 50  LYS I N   1 
ATOM   8226  C CA  . LYS E 1 44  ? -21.926 34.511  -49.598  1.00 74.52  ? 50  LYS I CA  1 
ATOM   8227  C C   . LYS E 1 44  ? -22.856 33.632  -48.771  1.00 79.52  ? 50  LYS I C   1 
ATOM   8228  O O   . LYS E 1 44  ? -23.130 32.483  -49.129  1.00 63.78  ? 50  LYS I O   1 
ATOM   8229  C CB  . LYS E 1 44  ? -22.751 35.459  -50.488  1.00 76.95  ? 50  LYS I CB  1 
ATOM   8230  C CG  . LYS E 1 44  ? -21.922 36.460  -51.291  1.00 84.68  ? 50  LYS I CG  1 
ATOM   8231  C CD  . LYS E 1 44  ? -22.803 37.454  -52.041  1.00 96.63  ? 50  LYS I CD  1 
ATOM   8232  C CE  . LYS E 1 44  ? -23.270 36.905  -53.383  1.00 95.40  ? 50  LYS I CE  1 
ATOM   8233  N NZ  . LYS E 1 44  ? -24.522 37.570  -53.850  1.00 87.65  ? 50  LYS I NZ  1 
ATOM   8234  N N   . LEU E 1 45  ? -23.336 34.182  -47.656  1.00 74.02  ? 51  LEU I N   1 
ATOM   8235  C CA  . LEU E 1 45  ? -24.343 33.521  -46.834  1.00 72.22  ? 51  LEU I CA  1 
ATOM   8236  C C   . LEU E 1 45  ? -25.723 33.915  -47.344  1.00 65.62  ? 51  LEU I C   1 
ATOM   8237  O O   . LEU E 1 45  ? -26.040 35.106  -47.430  1.00 73.41  ? 51  LEU I O   1 
ATOM   8238  C CB  . LEU E 1 45  ? -24.191 33.898  -45.360  1.00 60.89  ? 51  LEU I CB  1 
ATOM   8239  C CG  . LEU E 1 45  ? -22.889 33.535  -44.647  1.00 69.97  ? 51  LEU I CG  1 
ATOM   8240  C CD1 . LEU E 1 45  ? -23.011 33.815  -43.155  1.00 75.42  ? 51  LEU I CD1 1 
ATOM   8241  C CD2 . LEU E 1 45  ? -22.513 32.084  -44.894  1.00 61.43  ? 51  LEU I CD2 1 
ATOM   8242  N N   . CYS E 1 46  ? -26.542 32.923  -47.676  1.00 65.27  ? 52  CYS I N   1 
ATOM   8243  C CA  . CYS E 1 46  ? -27.814 33.158  -48.342  1.00 76.21  ? 52  CYS I CA  1 
ATOM   8244  C C   . CYS E 1 46  ? -28.971 32.668  -47.481  1.00 76.34  ? 52  CYS I C   1 
ATOM   8245  O O   . CYS E 1 46  ? -28.794 31.921  -46.514  1.00 74.55  ? 52  CYS I O   1 
ATOM   8246  C CB  . CYS E 1 46  ? -27.856 32.467  -49.711  1.00 67.73  ? 52  CYS I CB  1 
ATOM   8247  S SG  . CYS E 1 46  ? -26.531 32.935  -50.844  1.00 97.91  ? 52  CYS I SG  1 
ATOM   8248  N N   . ASP E 1 47  ? -30.171 33.110  -47.853  1.00 59.47  ? 53  ASP I N   1 
ATOM   8249  C CA  . ASP E 1 47  ? -31.385 32.584  -47.250  1.00 67.22  ? 53  ASP I CA  1 
ATOM   8250  C C   . ASP E 1 47  ? -31.522 31.100  -47.567  1.00 73.02  ? 53  ASP I C   1 
ATOM   8251  O O   . ASP E 1 47  ? -31.146 30.642  -48.649  1.00 74.45  ? 53  ASP I O   1 
ATOM   8252  C CB  . ASP E 1 47  ? -32.608 33.345  -47.766  1.00 69.89  ? 53  ASP I CB  1 
ATOM   8253  C CG  . ASP E 1 47  ? -32.549 34.826  -47.452  1.00 77.91  ? 53  ASP I CG  1 
ATOM   8254  O OD1 . ASP E 1 47  ? -31.631 35.238  -46.716  1.00 76.65  ? 53  ASP I OD1 1 
ATOM   8255  O OD2 . ASP E 1 47  ? -33.418 35.577  -47.943  1.00 82.83  ? 53  ASP I OD2 1 
ATOM   8256  N N   . LEU E 1 48  ? -32.059 30.347  -46.613  1.00 68.21  ? 54  LEU I N   1 
ATOM   8257  C CA  . LEU E 1 48  ? -32.279 28.915  -46.776  1.00 62.29  ? 54  LEU I CA  1 
ATOM   8258  C C   . LEU E 1 48  ? -33.765 28.691  -47.022  1.00 68.73  ? 54  LEU I C   1 
ATOM   8259  O O   . LEU E 1 48  ? -34.582 28.849  -46.109  1.00 64.36  ? 54  LEU I O   1 
ATOM   8260  C CB  . LEU E 1 48  ? -31.798 28.144  -45.550  1.00 63.70  ? 54  LEU I CB  1 
ATOM   8261  C CG  . LEU E 1 48  ? -31.801 26.620  -45.677  1.00 68.54  ? 54  LEU I CG  1 
ATOM   8262  C CD1 . LEU E 1 48  ? -30.751 26.166  -46.682  1.00 54.34  ? 54  LEU I CD1 1 
ATOM   8263  C CD2 . LEU E 1 48  ? -31.573 25.972  -44.320  1.00 68.34  ? 54  LEU I CD2 1 
ATOM   8264  N N   . ASN E 1 49  ? -34.107 28.324  -48.258  1.00 67.81  ? 55  ASN I N   1 
ATOM   8265  C CA  . ASN E 1 49  ? -35.495 28.099  -48.661  1.00 58.03  ? 55  ASN I CA  1 
ATOM   8266  C C   . ASN E 1 49  ? -36.363 29.320  -48.362  1.00 65.46  ? 55  ASN I C   1 
ATOM   8267  O O   . ASN E 1 49  ? -37.503 29.204  -47.906  1.00 72.77  ? 55  ASN I O   1 
ATOM   8268  C CB  . ASN E 1 49  ? -36.063 26.843  -47.997  1.00 53.80  ? 55  ASN I CB  1 
ATOM   8269  C CG  . ASN E 1 49  ? -35.189 25.624  -48.220  1.00 70.02  ? 55  ASN I CG  1 
ATOM   8270  O OD1 . ASN E 1 49  ? -34.706 25.010  -47.270  1.00 79.34  ? 55  ASN I OD1 1 
ATOM   8271  N ND2 . ASN E 1 49  ? -34.979 25.269  -49.482  1.00 69.94  ? 55  ASN I ND2 1 
ATOM   8272  N N   . GLY E 1 50  A -35.811 30.505  -48.615  1.00 60.73  ? 55  GLY I N   1 
ATOM   8273  C CA  . GLY E 1 50  A -36.559 31.739  -48.487  1.00 75.45  ? 55  GLY I CA  1 
ATOM   8274  C C   . GLY E 1 50  A -36.622 32.339  -47.101  1.00 77.89  ? 55  GLY I C   1 
ATOM   8275  O O   . GLY E 1 50  A -37.384 33.290  -46.893  1.00 66.90  ? 55  GLY I O   1 
ATOM   8276  N N   . VAL E 1 51  ? -35.852 31.824  -46.144  1.00 73.11  ? 56  VAL I N   1 
ATOM   8277  C CA  . VAL E 1 51  ? -35.838 32.341  -44.779  1.00 65.00  ? 56  VAL I CA  1 
ATOM   8278  C C   . VAL E 1 51  ? -34.433 32.850  -44.481  1.00 66.83  ? 56  VAL I C   1 
ATOM   8279  O O   . VAL E 1 51  ? -33.455 32.103  -44.612  1.00 68.06  ? 56  VAL I O   1 
ATOM   8280  C CB  . VAL E 1 51  ? -36.266 31.276  -43.757  1.00 70.46  ? 56  VAL I CB  1 
ATOM   8281  C CG1 . VAL E 1 51  ? -36.693 31.932  -42.453  1.00 70.54  ? 56  VAL I CG1 1 
ATOM   8282  C CG2 . VAL E 1 51  ? -37.387 30.416  -44.320  1.00 70.46  ? 56  VAL I CG2 1 
ATOM   8283  N N   . LYS E 1 52  ? -34.335 34.117  -44.084  1.00 59.44  ? 57  LYS I N   1 
ATOM   8284  C CA  . LYS E 1 52  ? -33.047 34.720  -43.791  1.00 60.93  ? 57  LYS I CA  1 
ATOM   8285  C C   . LYS E 1 52  ? -32.458 34.141  -42.505  1.00 74.52  ? 57  LYS I C   1 
ATOM   8286  O O   . LYS E 1 52  ? -33.190 33.829  -41.560  1.00 73.75  ? 57  LYS I O   1 
ATOM   8287  C CB  . LYS E 1 52  ? -33.187 36.234  -43.650  1.00 67.23  ? 57  LYS I CB  1 
ATOM   8288  C CG  . LYS E 1 52  ? -31.894 37.006  -43.874  1.00 80.45  ? 57  LYS I CG  1 
ATOM   8289  C CD  . LYS E 1 52  ? -31.740 38.168  -42.908  1.00 81.64  ? 57  LYS I CD  1 
ATOM   8290  C CE  . LYS E 1 52  ? -30.338 38.758  -42.990  1.00 75.30  ? 57  LYS I CE  1 
ATOM   8291  N NZ  . LYS E 1 52  ? -30.091 39.785  -41.940  1.00 79.82  ? 57  LYS I NZ  1 
ATOM   8292  N N   . PRO E 1 53  ? -31.141 33.975  -42.446  1.00 69.79  ? 58  PRO I N   1 
ATOM   8293  C CA  . PRO E 1 53  ? -30.502 33.552  -41.198  1.00 71.01  ? 58  PRO I CA  1 
ATOM   8294  C C   . PRO E 1 53  ? -30.415 34.684  -40.185  1.00 67.56  ? 58  PRO I C   1 
ATOM   8295  O O   . PRO E 1 53  ? -30.436 35.869  -40.521  1.00 71.77  ? 58  PRO I O   1 
ATOM   8296  C CB  . PRO E 1 53  ? -29.102 33.119  -41.647  1.00 58.43  ? 58  PRO I CB  1 
ATOM   8297  C CG  . PRO E 1 53  ? -28.851 33.925  -42.874  1.00 72.31  ? 58  PRO I CG  1 
ATOM   8298  C CD  . PRO E 1 53  ? -30.181 34.022  -43.566  1.00 70.83  ? 58  PRO I CD  1 
ATOM   8299  N N   . LEU E 1 54  ? -30.314 34.288  -38.919  1.00 59.97  ? 59  LEU I N   1 
ATOM   8300  C CA  . LEU E 1 54  ? -30.060 35.219  -37.826  1.00 59.90  ? 59  LEU I CA  1 
ATOM   8301  C C   . LEU E 1 54  ? -28.552 35.390  -37.697  1.00 65.74  ? 59  LEU I C   1 
ATOM   8302  O O   . LEU E 1 54  ? -27.845 34.458  -37.300  1.00 74.61  ? 59  LEU I O   1 
ATOM   8303  C CB  . LEU E 1 54  ? -30.674 34.712  -36.524  1.00 66.62  ? 59  LEU I CB  1 
ATOM   8304  C CG  . LEU E 1 54  ? -30.259 35.419  -35.233  1.00 69.49  ? 59  LEU I CG  1 
ATOM   8305  C CD1 . LEU E 1 54  ? -30.457 36.924  -35.338  1.00 64.40  ? 59  LEU I CD1 1 
ATOM   8306  C CD2 . LEU E 1 54  ? -31.037 34.858  -34.052  1.00 62.45  ? 59  LEU I CD2 1 
ATOM   8307  N N   . ILE E 1 55  ? -28.059 36.576  -38.034  1.00 61.93  ? 60  ILE I N   1 
ATOM   8308  C CA  . ILE E 1 55  ? -26.630 36.852  -38.059  1.00 64.12  ? 60  ILE I CA  1 
ATOM   8309  C C   . ILE E 1 55  ? -26.297 37.662  -36.811  1.00 68.71  ? 60  ILE I C   1 
ATOM   8310  O O   . ILE E 1 55  ? -26.481 38.881  -36.774  1.00 68.82  ? 60  ILE I O   1 
ATOM   8311  C CB  . ILE E 1 55  ? -26.215 37.578  -39.341  1.00 70.70  ? 60  ILE I CB  1 
ATOM   8312  C CG1 . ILE E 1 55  ? -26.565 36.723  -40.561  1.00 62.61  ? 60  ILE I CG1 1 
ATOM   8313  C CG2 . ILE E 1 55  ? -24.725 37.893  -39.318  1.00 54.69  ? 60  ILE I CG2 1 
ATOM   8314  C CD1 . ILE E 1 55  ? -26.051 37.280  -41.862  1.00 66.54  ? 60  ILE I CD1 1 
ATOM   8315  N N   . LEU E 1 56  ? -25.819 36.975  -35.778  1.00 75.41  ? 61  LEU I N   1 
ATOM   8316  C CA  . LEU E 1 56  ? -25.229 37.643  -34.625  1.00 65.39  ? 61  LEU I CA  1 
ATOM   8317  C C   . LEU E 1 56  ? -23.843 38.134  -35.023  1.00 80.10  ? 61  LEU I C   1 
ATOM   8318  O O   . LEU E 1 56  ? -22.950 37.327  -35.303  1.00 88.58  ? 61  LEU I O   1 
ATOM   8319  C CB  . LEU E 1 56  ? -25.159 36.685  -33.440  1.00 69.39  ? 61  LEU I CB  1 
ATOM   8320  C CG  . LEU E 1 56  ? -26.460 35.975  -33.055  1.00 70.00  ? 61  LEU I CG  1 
ATOM   8321  C CD1 . LEU E 1 56  ? -26.191 34.883  -32.033  1.00 58.43  ? 61  LEU I CD1 1 
ATOM   8322  C CD2 . LEU E 1 56  ? -27.481 36.967  -32.520  1.00 61.12  ? 61  LEU I CD2 1 
ATOM   8323  N N   . LYS E 1 57  ? -23.662 39.454  -35.066  1.00 80.30  ? 62  LYS I N   1 
ATOM   8324  C CA  . LYS E 1 57  ? -22.450 40.038  -35.630  1.00 72.96  ? 62  LYS I CA  1 
ATOM   8325  C C   . LYS E 1 57  ? -21.204 39.592  -34.876  1.00 81.33  ? 62  LYS I C   1 
ATOM   8326  O O   . LYS E 1 57  ? -20.365 38.873  -35.427  1.00 90.83  ? 62  LYS I O   1 
ATOM   8327  C CB  . LYS E 1 57  ? -22.548 41.565  -35.628  1.00 81.58  ? 62  LYS I CB  1 
ATOM   8328  C CG  . LYS E 1 57  ? -23.644 42.119  -36.524  1.00 83.08  ? 62  LYS I CG  1 
ATOM   8329  C CD  . LYS E 1 57  ? -23.405 41.744  -37.978  1.00 96.01  ? 62  LYS I CD  1 
ATOM   8330  C CE  . LYS E 1 57  ? -22.080 42.297  -38.483  1.00 91.27  ? 62  LYS I CE  1 
ATOM   8331  N NZ  . LYS E 1 57  ? -21.803 41.884  -39.887  1.00 95.10  ? 62  LYS I NZ  1 
ATOM   8332  N N   . ASP E 1 58  ? -21.080 39.999  -33.611  1.00 69.35  ? 63  ASP I N   1 
ATOM   8333  C CA  . ASP E 1 58  ? -19.979 39.560  -32.760  1.00 66.40  ? 63  ASP I CA  1 
ATOM   8334  C C   . ASP E 1 58  ? -20.488 39.104  -31.398  1.00 70.31  ? 63  ASP I C   1 
ATOM   8335  O O   . ASP E 1 58  ? -19.701 38.975  -30.454  1.00 68.45  ? 63  ASP I O   1 
ATOM   8336  C CB  . ASP E 1 58  ? -18.939 40.667  -32.586  1.00 70.09  ? 63  ASP I CB  1 
ATOM   8337  C CG  . ASP E 1 58  ? -17.521 40.133  -32.556  1.00 72.67  ? 63  ASP I CG  1 
ATOM   8338  O OD1 . ASP E 1 58  ? -16.579 40.951  -32.562  1.00 94.31  ? 63  ASP I OD1 1 
ATOM   8339  O OD2 . ASP E 1 58  ? -17.348 38.895  -32.554  1.00 81.85  ? 63  ASP I OD2 1 
ATOM   8340  N N   . CYS E 1 59  ? -21.789 38.868  -31.283  1.00 67.23  ? 64  CYS I N   1 
ATOM   8341  C CA  . CYS E 1 59  ? -22.431 38.486  -30.038  1.00 63.59  ? 64  CYS I CA  1 
ATOM   8342  C C   . CYS E 1 59  ? -22.679 36.983  -30.026  1.00 69.10  ? 64  CYS I C   1 
ATOM   8343  O O   . CYS E 1 59  ? -22.941 36.371  -31.064  1.00 55.25  ? 64  CYS I O   1 
ATOM   8344  C CB  . CYS E 1 59  ? -23.753 39.239  -29.873  1.00 62.17  ? 64  CYS I CB  1 
ATOM   8345  S SG  . CYS E 1 59  ? -24.399 39.361  -28.186  1.00 107.17 ? 64  CYS I SG  1 
ATOM   8346  N N   . SER E 1 60  ? -22.570 36.389  -28.842  1.00 60.09  ? 65  SER I N   1 
ATOM   8347  C CA  . SER E 1 60  ? -22.975 35.004  -28.679  1.00 57.19  ? 65  SER I CA  1 
ATOM   8348  C C   . SER E 1 60  ? -24.483 34.931  -28.452  1.00 52.82  ? 65  SER I C   1 
ATOM   8349  O O   . SER E 1 60  ? -25.155 35.940  -28.225  1.00 48.79  ? 65  SER I O   1 
ATOM   8350  C CB  . SER E 1 60  ? -22.231 34.356  -27.514  1.00 56.34  ? 65  SER I CB  1 
ATOM   8351  O OG  . SER E 1 60  ? -22.784 34.771  -26.278  1.00 63.81  ? 65  SER I OG  1 
ATOM   8352  N N   . VAL E 1 61  ? -25.018 33.711  -28.520  1.00 51.25  ? 66  VAL I N   1 
ATOM   8353  C CA  . VAL E 1 61  ? -26.445 33.521  -28.272  1.00 52.32  ? 66  VAL I CA  1 
ATOM   8354  C C   . VAL E 1 61  ? -26.799 33.959  -26.856  1.00 48.49  ? 66  VAL I C   1 
ATOM   8355  O O   . VAL E 1 61  ? -27.845 34.579  -26.626  1.00 63.38  ? 66  VAL I O   1 
ATOM   8356  C CB  . VAL E 1 61  ? -26.845 32.056  -28.536  1.00 47.21  ? 66  VAL I CB  1 
ATOM   8357  C CG1 . VAL E 1 61  ? -28.307 31.829  -28.181  1.00 44.89  ? 66  VAL I CG1 1 
ATOM   8358  C CG2 . VAL E 1 61  ? -26.594 31.694  -29.995  1.00 45.06  ? 66  VAL I CG2 1 
ATOM   8359  N N   . ALA E 1 62  ? -25.929 33.656  -25.888  1.00 46.61  ? 67  ALA I N   1 
ATOM   8360  C CA  . ALA E 1 62  ? -26.198 34.037  -24.506  1.00 55.37  ? 67  ALA I CA  1 
ATOM   8361  C C   . ALA E 1 62  ? -26.237 35.551  -24.344  1.00 52.25  ? 67  ALA I C   1 
ATOM   8362  O O   . ALA E 1 62  ? -27.116 36.086  -23.658  1.00 51.56  ? 67  ALA I O   1 
ATOM   8363  C CB  . ALA E 1 62  ? -25.149 33.428  -23.577  1.00 51.59  ? 67  ALA I CB  1 
ATOM   8364  N N   . GLY E 1 63  ? -25.289 36.259  -24.963  1.00 51.12  ? 68  GLY I N   1 
ATOM   8365  C CA  . GLY E 1 63  ? -25.300 37.711  -24.887  1.00 50.09  ? 68  GLY I CA  1 
ATOM   8366  C C   . GLY E 1 63  ? -26.496 38.318  -25.592  1.00 53.48  ? 68  GLY I C   1 
ATOM   8367  O O   . GLY E 1 63  ? -27.072 39.304  -25.124  1.00 60.97  ? 68  GLY I O   1 
ATOM   8368  N N   . TRP E 1 64  ? -26.880 37.744  -26.733  1.00 56.45  ? 69  TRP I N   1 
ATOM   8369  C CA  . TRP E 1 64  ? -28.073 38.201  -27.436  1.00 52.63  ? 69  TRP I CA  1 
ATOM   8370  C C   . TRP E 1 64  ? -29.327 37.973  -26.599  1.00 64.08  ? 69  TRP I C   1 
ATOM   8371  O O   . TRP E 1 64  ? -30.174 38.867  -26.482  1.00 62.41  ? 69  TRP I O   1 
ATOM   8372  C CB  . TRP E 1 64  ? -28.163 37.486  -28.785  1.00 47.39  ? 69  TRP I CB  1 
ATOM   8373  C CG  . TRP E 1 64  ? -29.474 37.603  -29.493  1.00 66.26  ? 69  TRP I CG  1 
ATOM   8374  C CD1 . TRP E 1 64  ? -30.048 38.740  -29.981  1.00 63.97  ? 69  TRP I CD1 1 
ATOM   8375  C CD2 . TRP E 1 64  ? -30.359 36.529  -29.829  1.00 61.08  ? 69  TRP I CD2 1 
ATOM   8376  N NE1 . TRP E 1 64  ? -31.247 38.442  -30.585  1.00 69.59  ? 69  TRP I NE1 1 
ATOM   8377  C CE2 . TRP E 1 64  ? -31.460 37.090  -30.504  1.00 67.39  ? 69  TRP I CE2 1 
ATOM   8378  C CE3 . TRP E 1 64  ? -30.331 35.147  -29.614  1.00 62.09  ? 69  TRP I CE3 1 
ATOM   8379  C CZ2 . TRP E 1 64  ? -32.523 36.318  -30.968  1.00 62.35  ? 69  TRP I CZ2 1 
ATOM   8380  C CZ3 . TRP E 1 64  ? -31.388 34.382  -30.076  1.00 62.89  ? 69  TRP I CZ3 1 
ATOM   8381  C CH2 . TRP E 1 64  ? -32.468 34.969  -30.745  1.00 63.97  ? 69  TRP I CH2 1 
ATOM   8382  N N   . LEU E 1 65  ? -29.453 36.791  -25.989  1.00 60.95  ? 70  LEU I N   1 
ATOM   8383  C CA  . LEU E 1 65  ? -30.649 36.476  -25.211  1.00 55.05  ? 70  LEU I CA  1 
ATOM   8384  C C   . LEU E 1 65  ? -30.733 37.306  -23.936  1.00 51.05  ? 70  LEU I C   1 
ATOM   8385  O O   . LEU E 1 65  ? -31.814 37.783  -23.572  1.00 58.34  ? 70  LEU I O   1 
ATOM   8386  C CB  . LEU E 1 65  ? -30.682 34.988  -24.868  1.00 51.08  ? 70  LEU I CB  1 
ATOM   8387  C CG  . LEU E 1 65  ? -31.051 34.007  -25.976  1.00 58.91  ? 70  LEU I CG  1 
ATOM   8388  C CD1 . LEU E 1 65  ? -31.086 32.603  -25.408  1.00 60.49  ? 70  LEU I CD1 1 
ATOM   8389  C CD2 . LEU E 1 65  ? -32.388 34.369  -26.603  1.00 48.07  ? 70  LEU I CD2 1 
ATOM   8390  N N   . LEU E 1 66  ? -29.614 37.473  -23.232  1.00 56.50  ? 71  LEU I N   1 
ATOM   8391  C CA  . LEU E 1 66  ? -29.629 38.197  -21.966  1.00 56.32  ? 71  LEU I CA  1 
ATOM   8392  C C   . LEU E 1 66  ? -29.571 39.709  -22.138  1.00 63.28  ? 71  LEU I C   1 
ATOM   8393  O O   . LEU E 1 66  ? -29.853 40.435  -21.178  1.00 51.48  ? 71  LEU I O   1 
ATOM   8394  C CB  . LEU E 1 66  ? -28.467 37.731  -21.084  1.00 43.77  ? 71  LEU I CB  1 
ATOM   8395  C CG  . LEU E 1 66  ? -28.633 36.336  -20.477  1.00 62.19  ? 71  LEU I CG  1 
ATOM   8396  C CD1 . LEU E 1 66  ? -27.341 35.871  -19.831  1.00 55.75  ? 71  LEU I CD1 1 
ATOM   8397  C CD2 . LEU E 1 66  ? -29.773 36.329  -19.465  1.00 47.01  ? 71  LEU I CD2 1 
ATOM   8398  N N   . GLY E 1 67  ? -29.226 40.198  -23.324  1.00 55.28  ? 72  GLY I N   1 
ATOM   8399  C CA  . GLY E 1 67  ? -29.124 41.625  -23.545  1.00 53.80  ? 72  GLY I CA  1 
ATOM   8400  C C   . GLY E 1 67  ? -27.804 42.207  -23.086  1.00 59.59  ? 72  GLY I C   1 
ATOM   8401  O O   . GLY E 1 67  ? -27.780 43.194  -22.344  1.00 61.01  ? 72  GLY I O   1 
ATOM   8402  N N   . ASN E 1 68  ? -26.702 41.598  -23.515  1.00 56.37  ? 73  ASN I N   1 
ATOM   8403  C CA  . ASN E 1 68  ? -25.379 42.142  -23.249  1.00 58.85  ? 73  ASN I CA  1 
ATOM   8404  C C   . ASN E 1 68  ? -25.322 43.566  -23.789  1.00 61.31  ? 73  ASN I C   1 
ATOM   8405  O O   . ASN E 1 68  ? -25.595 43.778  -24.980  1.00 60.57  ? 73  ASN I O   1 
ATOM   8406  C CB  . ASN E 1 68  ? -24.310 41.264  -23.907  1.00 53.19  ? 73  ASN I CB  1 
ATOM   8407  C CG  . ASN E 1 68  ? -22.889 41.656  -23.519  1.00 65.28  ? 73  ASN I CG  1 
ATOM   8408  O OD1 . ASN E 1 68  ? -22.581 42.829  -23.311  1.00 70.42  ? 73  ASN I OD1 1 
ATOM   8409  N ND2 . ASN E 1 68  ? -22.010 40.664  -23.434  1.00 60.14  ? 73  ASN I ND2 1 
ATOM   8410  N N   . PRO E 1 69  ? -24.997 44.563  -22.960  1.00 69.39  ? 74  PRO I N   1 
ATOM   8411  C CA  . PRO E 1 69  ? -25.072 45.959  -23.426  1.00 73.74  ? 74  PRO I CA  1 
ATOM   8412  C C   . PRO E 1 69  ? -24.168 46.270  -24.606  1.00 72.57  ? 74  PRO I C   1 
ATOM   8413  O O   . PRO E 1 69  ? -24.501 47.152  -25.408  1.00 81.70  ? 74  PRO I O   1 
ATOM   8414  C CB  . PRO E 1 69  ? -24.677 46.768  -22.180  1.00 73.28  ? 74  PRO I CB  1 
ATOM   8415  C CG  . PRO E 1 69  ? -23.977 45.795  -21.283  1.00 78.26  ? 74  PRO I CG  1 
ATOM   8416  C CD  . PRO E 1 69  ? -24.621 44.472  -21.540  1.00 62.35  ? 74  PRO I CD  1 
ATOM   8417  N N   . MET E 1 70  ? -23.032 45.581  -24.743  1.00 77.86  ? 75  MET I N   1 
ATOM   8418  C CA  . MET E 1 70  ? -22.157 45.830  -25.884  1.00 80.38  ? 75  MET I CA  1 
ATOM   8419  C C   . MET E 1 70  ? -22.709 45.247  -27.178  1.00 79.14  ? 75  MET I C   1 
ATOM   8420  O O   . MET E 1 70  ? -22.305 45.683  -28.261  1.00 88.99  ? 75  MET I O   1 
ATOM   8421  C CB  . MET E 1 70  ? -20.756 45.276  -25.615  1.00 73.29  ? 75  MET I CB  1 
ATOM   8422  C CG  . MET E 1 70  ? -19.967 46.074  -24.587  1.00 80.64  ? 75  MET I CG  1 
ATOM   8423  S SD  . MET E 1 70  ? -20.145 45.453  -22.903  1.00 112.17 ? 75  MET I SD  1 
ATOM   8424  C CE  . MET E 1 70  ? -18.702 44.396  -22.775  1.00 58.39  ? 75  MET I CE  1 
ATOM   8425  N N   . CYS E 1 71  ? -23.610 44.273  -27.095  1.00 81.12  ? 76  CYS I N   1 
ATOM   8426  C CA  . CYS E 1 71  ? -24.270 43.757  -28.284  1.00 87.94  ? 76  CYS I CA  1 
ATOM   8427  C C   . CYS E 1 71  ? -25.349 44.728  -28.747  1.00 101.59 ? 76  CYS I C   1 
ATOM   8428  O O   . CYS E 1 71  ? -25.949 45.452  -27.946  1.00 100.52 ? 76  CYS I O   1 
ATOM   8429  C CB  . CYS E 1 71  ? -24.877 42.377  -28.015  1.00 84.50  ? 76  CYS I CB  1 
ATOM   8430  S SG  . CYS E 1 71  ? -23.664 41.129  -27.508  1.00 89.48  ? 76  CYS I SG  1 
ATOM   8431  N N   . ASP E 1 72  ? -25.592 44.735  -30.056  1.00 113.94 ? 77  ASP I N   1 
ATOM   8432  C CA  . ASP E 1 72  ? -26.534 45.681  -30.640  1.00 117.85 ? 77  ASP I CA  1 
ATOM   8433  C C   . ASP E 1 72  ? -27.930 45.476  -30.064  1.00 112.68 ? 77  ASP I C   1 
ATOM   8434  O O   . ASP E 1 72  ? -28.314 44.366  -29.683  1.00 108.75 ? 77  ASP I O   1 
ATOM   8435  C CB  . ASP E 1 72  ? -26.570 45.529  -32.162  1.00 107.81 ? 77  ASP I CB  1 
ATOM   8436  C CG  . ASP E 1 72  ? -25.201 45.677  -32.796  1.00 107.64 ? 77  ASP I CG  1 
ATOM   8437  O OD1 . ASP E 1 72  ? -24.323 46.322  -32.184  1.00 115.84 ? 77  ASP I OD1 1 
ATOM   8438  O OD2 . ASP E 1 72  ? -25.003 45.150  -33.911  1.00 115.01 ? 77  ASP I OD2 1 
ATOM   8439  N N   . GLU E 1 73  ? -28.685 46.571  -29.989  1.00 112.76 ? 78  GLU I N   1 
ATOM   8440  C CA  . GLU E 1 73  ? -30.033 46.512  -29.440  1.00 112.36 ? 78  GLU I CA  1 
ATOM   8441  C C   . GLU E 1 73  ? -30.894 45.559  -30.258  1.00 108.21 ? 78  GLU I C   1 
ATOM   8442  O O   . GLU E 1 73  ? -30.758 45.466  -31.482  1.00 97.52  ? 78  GLU I O   1 
ATOM   8443  C CB  . GLU E 1 73  ? -30.659 47.909  -29.411  1.00 113.23 ? 78  GLU I CB  1 
ATOM   8444  C CG  . GLU E 1 73  ? -32.050 47.952  -28.792  1.00 114.22 ? 78  GLU I CG  1 
ATOM   8445  C CD  . GLU E 1 73  ? -32.089 47.342  -27.402  1.00 115.99 ? 78  GLU I CD  1 
ATOM   8446  O OE1 . GLU E 1 73  ? -31.446 47.898  -26.487  1.00 116.48 ? 78  GLU I OE1 1 
ATOM   8447  O OE2 . GLU E 1 73  ? -32.754 46.299  -27.228  1.00 111.18 ? 78  GLU I OE2 1 
ATOM   8448  N N   . PHE E 1 74  ? -31.770 44.835  -29.565  1.00 111.74 ? 79  PHE I N   1 
ATOM   8449  C CA  . PHE E 1 74  ? -32.576 43.786  -30.178  1.00 108.06 ? 79  PHE I CA  1 
ATOM   8450  C C   . PHE E 1 74  ? -33.354 44.314  -31.373  1.00 108.69 ? 79  PHE I C   1 
ATOM   8451  O O   . PHE E 1 74  ? -34.175 45.226  -31.242  1.00 108.29 ? 79  PHE I O   1 
ATOM   8452  C CB  . PHE E 1 74  ? -33.533 43.201  -29.135  1.00 94.96  ? 79  PHE I CB  1 
ATOM   8453  C CG  . PHE E 1 74  ? -34.447 42.133  -29.675  1.00 106.07 ? 79  PHE I CG  1 
ATOM   8454  C CD1 . PHE E 1 74  ? -34.023 40.816  -29.758  1.00 89.74  ? 79  PHE I CD1 1 
ATOM   8455  C CD2 . PHE E 1 74  ? -35.733 42.445  -30.090  1.00 103.02 ? 79  PHE I CD2 1 
ATOM   8456  C CE1 . PHE E 1 74  ? -34.862 39.832  -30.250  1.00 75.53  ? 79  PHE I CE1 1 
ATOM   8457  C CE2 . PHE E 1 74  ? -36.574 41.466  -30.583  1.00 97.73  ? 79  PHE I CE2 1 
ATOM   8458  C CZ  . PHE E 1 74  ? -36.139 40.158  -30.664  1.00 94.99  ? 79  PHE I CZ  1 
ATOM   8459  N N   . ILE E 1 75  ? -33.084 43.738  -32.541  1.00 104.87 ? 80  ILE I N   1 
ATOM   8460  C CA  . ILE E 1 75  ? -33.824 44.031  -33.762  1.00 109.29 ? 80  ILE I CA  1 
ATOM   8461  C C   . ILE E 1 75  ? -34.792 42.885  -34.002  1.00 108.93 ? 80  ILE I C   1 
ATOM   8462  O O   . ILE E 1 75  ? -34.411 41.712  -33.895  1.00 100.76 ? 80  ILE I O   1 
ATOM   8463  C CB  . ILE E 1 75  ? -32.883 44.217  -34.964  1.00 96.17  ? 80  ILE I CB  1 
ATOM   8464  C CG1 . ILE E 1 75  ? -31.782 45.225  -34.635  1.00 92.35  ? 80  ILE I CG1 1 
ATOM   8465  C CG2 . ILE E 1 75  ? -33.670 44.660  -36.185  1.00 68.20  ? 80  ILE I CG2 1 
ATOM   8466  C CD1 . ILE E 1 75  ? -32.299 46.615  -34.347  1.00 90.66  ? 80  ILE I CD1 1 
ATOM   8467  N N   . ARG E 1 76  ? -36.042 43.216  -34.319  1.00 99.97  ? 81  ARG I N   1 
ATOM   8468  C CA  . ARG E 1 76  ? -37.045 42.171  -34.485  1.00 105.72 ? 81  ARG I CA  1 
ATOM   8469  C C   . ARG E 1 76  ? -36.711 41.283  -35.676  1.00 106.99 ? 81  ARG I C   1 
ATOM   8470  O O   . ARG E 1 76  ? -36.864 41.694  -36.831  1.00 103.06 ? 81  ARG I O   1 
ATOM   8471  C CB  . ARG E 1 76  ? -38.446 42.761  -34.665  1.00 111.05 ? 81  ARG I CB  1 
ATOM   8472  C CG  . ARG E 1 76  ? -38.749 43.994  -33.826  1.00 119.20 ? 81  ARG I CG  1 
ATOM   8473  C CD  . ARG E 1 76  ? -38.644 43.733  -32.333  1.00 120.54 ? 81  ARG I CD  1 
ATOM   8474  N NE  . ARG E 1 76  ? -39.249 42.468  -31.933  1.00 129.03 ? 81  ARG I NE  1 
ATOM   8475  C CZ  . ARG E 1 76  ? -40.553 42.252  -31.837  1.00 124.99 ? 81  ARG I CZ  1 
ATOM   8476  N NH1 . ARG E 1 76  ? -41.436 43.184  -32.155  1.00 128.55 ? 81  ARG I NH1 1 
ATOM   8477  N NH2 . ARG E 1 76  ? -40.981 41.067  -31.415  1.00 105.95 ? 81  ARG I NH2 1 
ATOM   8478  N N   . VAL E 1 77  ? -36.240 40.072  -35.401  1.00 103.47 ? 82  VAL I N   1 
ATOM   8479  C CA  . VAL E 1 77  ? -36.100 39.039  -36.422  1.00 90.77  ? 82  VAL I CA  1 
ATOM   8480  C C   . VAL E 1 77  ? -37.108 37.959  -36.056  1.00 78.29  ? 82  VAL I C   1 
ATOM   8481  O O   . VAL E 1 77  ? -36.775 37.023  -35.314  1.00 87.36  ? 82  VAL I O   1 
ATOM   8482  C CB  . VAL E 1 77  ? -34.666 38.490  -36.493  1.00 90.54  ? 82  VAL I CB  1 
ATOM   8483  C CG1 . VAL E 1 77  ? -34.478 37.650  -37.749  1.00 82.97  ? 82  VAL I CG1 1 
ATOM   8484  C CG2 . VAL E 1 77  ? -33.657 39.629  -36.448  1.00 90.80  ? 82  VAL I CG2 1 
ATOM   8485  N N   . PRO E 1 78  ? -38.351 38.056  -36.537  1.00 76.56  ? 83  PRO I N   1 
ATOM   8486  C CA  . PRO E 1 78  ? -39.398 37.133  -36.072  1.00 68.79  ? 83  PRO I CA  1 
ATOM   8487  C C   . PRO E 1 78  ? -39.172 35.688  -36.478  1.00 63.30  ? 83  PRO I C   1 
ATOM   8488  O O   . PRO E 1 78  ? -39.854 34.807  -35.942  1.00 74.41  ? 83  PRO I O   1 
ATOM   8489  C CB  . PRO E 1 78  ? -40.672 37.698  -36.714  1.00 78.93  ? 83  PRO I CB  1 
ATOM   8490  C CG  . PRO E 1 78  ? -40.187 38.428  -37.923  1.00 80.46  ? 83  PRO I CG  1 
ATOM   8491  C CD  . PRO E 1 78  ? -38.852 39.006  -37.544  1.00 81.44  ? 83  PRO I CD  1 
ATOM   8492  N N   . GLU E 1 79  A -38.254 35.414  -37.400  1.00 68.32  ? 83  GLU I N   1 
ATOM   8493  C CA  . GLU E 1 79  A -37.966 34.043  -37.796  1.00 68.09  ? 83  GLU I CA  1 
ATOM   8494  C C   . GLU E 1 79  A -36.568 33.986  -38.391  1.00 60.77  ? 83  GLU I C   1 
ATOM   8495  O O   . GLU E 1 79  A -36.022 34.998  -38.837  1.00 70.94  ? 83  GLU I O   1 
ATOM   8496  C CB  . GLU E 1 79  A -38.997 33.519  -38.800  1.00 71.66  ? 83  GLU I CB  1 
ATOM   8497  C CG  . GLU E 1 79  A -39.036 34.300  -40.104  1.00 79.06  ? 83  GLU I CG  1 
ATOM   8498  C CD  . GLU E 1 79  A -39.939 33.658  -41.140  1.00 97.93  ? 83  GLU I CD  1 
ATOM   8499  O OE1 . GLU E 1 79  A -40.166 34.281  -42.199  1.00 105.58 ? 83  GLU I OE1 1 
ATOM   8500  O OE2 . GLU E 1 79  A -40.418 32.531  -40.897  1.00 96.95  ? 83  GLU I OE2 1 
ATOM   8501  N N   . TRP E 1 80  ? -35.997 32.784  -38.387  1.00 66.48  ? 84  TRP I N   1 
ATOM   8502  C CA  . TRP E 1 80  ? -34.723 32.539  -39.048  1.00 57.91  ? 84  TRP I CA  1 
ATOM   8503  C C   . TRP E 1 80  ? -34.593 31.049  -39.329  1.00 62.76  ? 84  TRP I C   1 
ATOM   8504  O O   . TRP E 1 80  ? -35.292 30.222  -38.738  1.00 53.58  ? 84  TRP I O   1 
ATOM   8505  C CB  . TRP E 1 80  ? -33.537 33.046  -38.217  1.00 51.63  ? 84  TRP I CB  1 
ATOM   8506  C CG  . TRP E 1 80  ? -33.466 32.496  -36.826  1.00 66.40  ? 84  TRP I CG  1 
ATOM   8507  C CD1 . TRP E 1 80  ? -32.846 31.346  -36.428  1.00 59.60  ? 84  TRP I CD1 1 
ATOM   8508  C CD2 . TRP E 1 80  ? -34.017 33.084  -35.642  1.00 61.97  ? 84  TRP I CD2 1 
ATOM   8509  N NE1 . TRP E 1 80  ? -32.987 31.177  -35.073  1.00 62.53  ? 84  TRP I NE1 1 
ATOM   8510  C CE2 . TRP E 1 80  ? -33.701 32.231  -34.566  1.00 58.46  ? 84  TRP I CE2 1 
ATOM   8511  C CE3 . TRP E 1 80  ? -34.752 34.246  -35.387  1.00 61.97  ? 84  TRP I CE3 1 
ATOM   8512  C CZ2 . TRP E 1 80  ? -34.091 32.504  -33.258  1.00 59.72  ? 84  TRP I CZ2 1 
ATOM   8513  C CZ3 . TRP E 1 80  ? -35.140 34.514  -34.088  1.00 52.55  ? 84  TRP I CZ3 1 
ATOM   8514  C CH2 . TRP E 1 80  ? -34.810 33.647  -33.040  1.00 64.16  ? 84  TRP I CH2 1 
ATOM   8515  N N   . SER E 1 81  ? -33.691 30.722  -40.253  1.00 57.93  ? 85  SER I N   1 
ATOM   8516  C CA  . SER E 1 81  ? -33.452 29.339  -40.647  1.00 61.45  ? 85  SER I CA  1 
ATOM   8517  C C   . SER E 1 81  ? -32.187 28.754  -40.037  1.00 57.20  ? 85  SER I C   1 
ATOM   8518  O O   . SER E 1 81  ? -32.107 27.535  -39.860  1.00 47.30  ? 85  SER I O   1 
ATOM   8519  C CB  . SER E 1 81  ? -33.375 29.231  -42.173  1.00 57.74  ? 85  SER I CB  1 
ATOM   8520  O OG  . SER E 1 81  ? -32.462 30.176  -42.705  1.00 64.93  ? 85  SER I OG  1 
ATOM   8521  N N   . TYR E 1 82  ? -31.199 29.588  -39.725  1.00 52.76  ? 86  TYR I N   1 
ATOM   8522  C CA  . TYR E 1 82  ? -30.009 29.147  -39.012  1.00 54.45  ? 86  TYR I CA  1 
ATOM   8523  C C   . TYR E 1 82  ? -29.356 30.367  -38.380  1.00 56.04  ? 86  TYR I C   1 
ATOM   8524  O O   . TYR E 1 82  ? -29.648 31.508  -38.746  1.00 66.85  ? 86  TYR I O   1 
ATOM   8525  C CB  . TYR E 1 82  ? -29.031 28.393  -39.928  1.00 57.32  ? 86  TYR I CB  1 
ATOM   8526  C CG  . TYR E 1 82  ? -28.504 29.167  -41.122  1.00 64.77  ? 86  TYR I CG  1 
ATOM   8527  C CD1 . TYR E 1 82  ? -29.291 29.374  -42.249  1.00 63.32  ? 86  TYR I CD1 1 
ATOM   8528  C CD2 . TYR E 1 82  ? -27.204 29.659  -41.135  1.00 58.61  ? 86  TYR I CD2 1 
ATOM   8529  C CE1 . TYR E 1 82  ? -28.806 30.070  -43.343  1.00 65.12  ? 86  TYR I CE1 1 
ATOM   8530  C CE2 . TYR E 1 82  ? -26.711 30.354  -42.222  1.00 68.52  ? 86  TYR I CE2 1 
ATOM   8531  C CZ  . TYR E 1 82  ? -27.515 30.557  -43.323  1.00 67.93  ? 86  TYR I CZ  1 
ATOM   8532  O OH  . TYR E 1 82  ? -27.022 31.250  -44.405  1.00 62.34  ? 86  TYR I OH  1 
ATOM   8533  N N   . ILE E 1 83  ? -28.482 30.109  -37.412  1.00 58.29  ? 87  ILE I N   1 
ATOM   8534  C CA  . ILE E 1 83  ? -27.788 31.153  -36.665  1.00 59.50  ? 87  ILE I CA  1 
ATOM   8535  C C   . ILE E 1 83  ? -26.340 31.193  -37.128  1.00 54.80  ? 87  ILE I C   1 
ATOM   8536  O O   . ILE E 1 83  ? -25.713 30.146  -37.330  1.00 59.72  ? 87  ILE I O   1 
ATOM   8537  C CB  . ILE E 1 83  ? -27.872 30.919  -35.143  1.00 59.75  ? 87  ILE I CB  1 
ATOM   8538  C CG1 . ILE E 1 83  ? -29.323 31.001  -34.663  1.00 48.87  ? 87  ILE I CG1 1 
ATOM   8539  C CG2 . ILE E 1 83  ? -27.010 31.924  -34.389  1.00 46.29  ? 87  ILE I CG2 1 
ATOM   8540  C CD1 . ILE E 1 83  ? -29.474 30.872  -33.166  1.00 47.74  ? 87  ILE I CD1 1 
ATOM   8541  N N   . VAL E 1 84  ? -25.815 32.400  -37.314  1.00 54.53  ? 88  VAL I N   1 
ATOM   8542  C CA  . VAL E 1 84  ? -24.424 32.604  -37.698  1.00 57.77  ? 88  VAL I CA  1 
ATOM   8543  C C   . VAL E 1 84  ? -23.711 33.305  -36.550  1.00 49.85  ? 88  VAL I C   1 
ATOM   8544  O O   . VAL E 1 84  ? -24.055 34.438  -36.189  1.00 62.93  ? 88  VAL I O   1 
ATOM   8545  C CB  . VAL E 1 84  ? -24.304 33.409  -39.000  1.00 65.68  ? 88  VAL I CB  1 
ATOM   8546  C CG1 . VAL E 1 84  ? -22.843 33.633  -39.349  1.00 54.33  ? 88  VAL I CG1 1 
ATOM   8547  C CG2 . VAL E 1 84  ? -25.018 32.688  -40.133  1.00 54.45  ? 88  VAL I CG2 1 
ATOM   8548  N N   . GLU E 1 85  ? -22.724 32.626  -35.977  1.00 53.06  ? 89  GLU I N   1 
ATOM   8549  C CA  . GLU E 1 85  ? -21.824 33.198  -34.991  1.00 56.65  ? 89  GLU I CA  1 
ATOM   8550  C C   . GLU E 1 85  ? -20.416 33.224  -35.564  1.00 60.78  ? 89  GLU I C   1 
ATOM   8551  O O   . GLU E 1 85  ? -20.066 32.415  -36.427  1.00 53.78  ? 89  GLU I O   1 
ATOM   8552  C CB  . GLU E 1 85  ? -21.814 32.392  -33.678  1.00 65.38  ? 89  GLU I CB  1 
ATOM   8553  C CG  . GLU E 1 85  ? -22.973 32.657  -32.730  1.00 59.35  ? 89  GLU I CG  1 
ATOM   8554  C CD  . GLU E 1 85  ? -22.849 31.855  -31.441  1.00 80.95  ? 89  GLU I CD  1 
ATOM   8555  O OE1 . GLU E 1 85  ? -22.112 30.845  -31.436  1.00 67.00  ? 89  GLU I OE1 1 
ATOM   8556  O OE2 . GLU E 1 85  ? -23.479 32.234  -30.430  1.00 73.74  ? 89  GLU I OE2 1 
ATOM   8557  N N   . ARG E 1 86  ? -19.610 34.164  -35.084  1.00 59.27  ? 90  ARG I N   1 
ATOM   8558  C CA  . ARG E 1 86  ? -18.185 34.106  -35.356  1.00 51.83  ? 90  ARG I CA  1 
ATOM   8559  C C   . ARG E 1 86  ? -17.562 32.960  -34.567  1.00 65.33  ? 90  ARG I C   1 
ATOM   8560  O O   . ARG E 1 86  ? -18.168 32.413  -33.640  1.00 73.31  ? 90  ARG I O   1 
ATOM   8561  C CB  . ARG E 1 86  ? -17.518 35.432  -34.996  1.00 67.45  ? 90  ARG I CB  1 
ATOM   8562  C CG  . ARG E 1 86  ? -18.190 36.637  -35.634  1.00 59.33  ? 90  ARG I CG  1 
ATOM   8563  C CD  . ARG E 1 86  ? -17.435 37.110  -36.858  1.00 87.97  ? 90  ARG I CD  1 
ATOM   8564  N NE  . ARG E 1 86  ? -16.266 37.898  -36.487  1.00 86.48  ? 90  ARG I NE  1 
ATOM   8565  C CZ  . ARG E 1 86  ? -15.290 38.230  -37.320  1.00 74.98  ? 90  ARG I CZ  1 
ATOM   8566  N NH1 . ARG E 1 86  ? -15.297 37.841  -38.584  1.00 81.46  ? 90  ARG I NH1 1 
ATOM   8567  N NH2 . ARG E 1 86  ? -14.277 38.965  -36.871  1.00 84.01  ? 90  ARG I NH2 1 
ATOM   8568  N N   . ALA E 1 87  ? -16.339 32.587  -34.951  1.00 64.70  ? 91  ALA I N   1 
ATOM   8569  C CA  . ALA E 1 87  ? -15.688 31.442  -34.322  1.00 60.14  ? 91  ALA I CA  1 
ATOM   8570  C C   . ALA E 1 87  ? -15.568 31.638  -32.815  1.00 62.15  ? 91  ALA I C   1 
ATOM   8571  O O   . ALA E 1 87  ? -15.861 30.727  -32.032  1.00 67.75  ? 91  ALA I O   1 
ATOM   8572  C CB  . ALA E 1 87  ? -14.314 31.209  -34.950  1.00 53.97  ? 91  ALA I CB  1 
ATOM   8573  N N   . ASN E 1 88  ? -15.148 32.828  -32.390  1.00 57.49  ? 92  ASN I N   1 
ATOM   8574  C CA  . ASN E 1 88  ? -15.055 33.183  -30.975  1.00 56.91  ? 92  ASN I CA  1 
ATOM   8575  C C   . ASN E 1 88  ? -15.754 34.519  -30.771  1.00 65.06  ? 92  ASN I C   1 
ATOM   8576  O O   . ASN E 1 88  ? -15.127 35.582  -30.881  1.00 65.62  ? 92  ASN I O   1 
ATOM   8577  C CB  . ASN E 1 88  ? -13.601 33.241  -30.514  1.00 52.25  ? 92  ASN I CB  1 
ATOM   8578  C CG  . ASN E 1 88  ? -12.847 31.958  -30.805  1.00 67.47  ? 92  ASN I CG  1 
ATOM   8579  O OD1 . ASN E 1 88  ? -11.817 31.969  -31.479  1.00 83.22  ? 92  ASN I OD1 1 
ATOM   8580  N ND2 . ASN E 1 88  ? -13.360 30.842  -30.299  1.00 68.42  ? 92  ASN I ND2 1 
ATOM   8581  N N   . PRO E 1 89  ? -17.060 34.508  -30.495  1.00 72.42  ? 93  PRO I N   1 
ATOM   8582  C CA  . PRO E 1 89  ? -17.777 35.771  -30.278  1.00 60.11  ? 93  PRO I CA  1 
ATOM   8583  C C   . PRO E 1 89  ? -17.169 36.566  -29.132  1.00 65.79  ? 93  PRO I C   1 
ATOM   8584  O O   . PRO E 1 89  ? -16.822 36.017  -28.084  1.00 70.55  ? 93  PRO I O   1 
ATOM   8585  C CB  . PRO E 1 89  ? -19.205 35.316  -29.954  1.00 63.39  ? 93  PRO I CB  1 
ATOM   8586  C CG  . PRO E 1 89  ? -19.321 33.961  -30.576  1.00 57.10  ? 93  PRO I CG  1 
ATOM   8587  C CD  . PRO E 1 89  ? -17.958 33.342  -30.443  1.00 64.64  ? 93  PRO I CD  1 
ATOM   8588  N N   . ALA E 1 90  ? -17.047 37.878  -29.343  1.00 64.83  ? 94  ALA I N   1 
ATOM   8589  C CA  . ALA E 1 90  ? -16.381 38.728  -28.362  1.00 65.83  ? 94  ALA I CA  1 
ATOM   8590  C C   . ALA E 1 90  ? -17.288 39.055  -27.181  1.00 65.16  ? 94  ALA I C   1 
ATOM   8591  O O   . ALA E 1 90  ? -16.853 38.987  -26.026  1.00 77.67  ? 94  ALA I O   1 
ATOM   8592  C CB  . ALA E 1 90  ? -15.895 40.014  -29.028  1.00 64.57  ? 94  ALA I CB  1 
ATOM   8593  N N   . ASN E 1 91  ? -18.542 39.409  -27.446  1.00 61.64  ? 95  ASN I N   1 
ATOM   8594  C CA  . ASN E 1 91  ? -19.486 39.804  -26.402  1.00 69.22  ? 95  ASN I CA  1 
ATOM   8595  C C   . ASN E 1 91  ? -20.407 38.623  -26.118  1.00 68.39  ? 95  ASN I C   1 
ATOM   8596  O O   . ASN E 1 91  ? -21.391 38.404  -26.830  1.00 65.55  ? 95  ASN I O   1 
ATOM   8597  C CB  . ASN E 1 91  ? -20.276 41.038  -26.824  1.00 57.67  ? 95  ASN I CB  1 
ATOM   8598  C CG  . ASN E 1 91  ? -19.388 42.161  -27.323  1.00 63.52  ? 95  ASN I CG  1 
ATOM   8599  O OD1 . ASN E 1 91  ? -19.567 42.660  -28.434  1.00 70.80  ? 95  ASN I OD1 1 
ATOM   8600  N ND2 . ASN E 1 91  ? -18.425 42.564  -26.504  1.00 69.53  ? 95  ASN I ND2 1 
ATOM   8601  N N   . ASP E 1 92  ? -20.086 37.854  -25.078  1.00 70.29  ? 96  ASP I N   1 
ATOM   8602  C CA  . ASP E 1 92  ? -20.898 36.709  -24.689  1.00 69.97  ? 96  ASP I CA  1 
ATOM   8603  C C   . ASP E 1 92  ? -21.543 36.890  -23.321  1.00 73.36  ? 96  ASP I C   1 
ATOM   8604  O O   . ASP E 1 92  ? -22.771 36.897  -23.209  1.00 84.21  ? 96  ASP I O   1 
ATOM   8605  C CB  . ASP E 1 92  ? -20.033 35.440  -24.716  1.00 60.04  ? 96  ASP I CB  1 
ATOM   8606  C CG  . ASP E 1 92  ? -20.650 34.293  -23.936  1.00 73.10  ? 96  ASP I CG  1 
ATOM   8607  O OD1 . ASP E 1 92  ? -21.822 33.946  -24.201  1.00 71.23  ? 96  ASP I OD1 1 
ATOM   8608  O OD2 . ASP E 1 92  ? -19.957 33.732  -23.061  1.00 73.69  ? 96  ASP I OD2 1 
ATOM   8609  N N   . LEU E 1 93  A -20.743 37.077  -22.275  1.00 64.11  ? 96  LEU I N   1 
ATOM   8610  C CA  . LEU E 1 93  A -21.253 37.276  -20.919  1.00 65.42  ? 96  LEU I CA  1 
ATOM   8611  C C   . LEU E 1 93  A -20.359 38.331  -20.280  1.00 59.21  ? 96  LEU I C   1 
ATOM   8612  O O   . LEU E 1 93  A -19.280 38.009  -19.774  1.00 63.11  ? 96  LEU I O   1 
ATOM   8613  C CB  . LEU E 1 93  A -21.257 35.981  -20.113  1.00 54.10  ? 96  LEU I CB  1 
ATOM   8614  C CG  . LEU E 1 93  A -22.328 34.931  -20.426  1.00 64.98  ? 96  LEU I CG  1 
ATOM   8615  C CD1 . LEU E 1 93  A -22.061 33.642  -19.664  1.00 44.56  ? 96  LEU I CD1 1 
ATOM   8616  C CD2 . LEU E 1 93  A -23.717 35.456  -20.104  1.00 55.96  ? 96  LEU I CD2 1 
ATOM   8617  N N   . CYS E 1 94  ? -20.804 39.589  -20.323  1.00 55.26  ? 97  CYS I N   1 
ATOM   8618  C CA  . CYS E 1 94  ? -20.000 40.669  -19.765  1.00 54.74  ? 97  CYS I CA  1 
ATOM   8619  C C   . CYS E 1 94  ? -19.765 40.460  -18.275  1.00 57.07  ? 97  CYS I C   1 
ATOM   8620  O O   . CYS E 1 94  ? -18.638 40.614  -17.788  1.00 56.98  ? 97  CYS I O   1 
ATOM   8621  C CB  . CYS E 1 94  ? -20.670 42.016  -20.039  1.00 51.78  ? 97  CYS I CB  1 
ATOM   8622  S SG  . CYS E 1 94  ? -22.385 42.163  -19.482  1.00 71.73  ? 97  CYS I SG  1 
ATOM   8623  N N   . TYR E 1 95  ? -20.805 40.092  -17.539  1.00 46.96  ? 98  TYR I N   1 
ATOM   8624  C CA  . TYR E 1 95  ? -20.535 39.649  -16.178  1.00 58.55  ? 98  TYR I CA  1 
ATOM   8625  C C   . TYR E 1 95  ? -20.186 38.164  -16.191  1.00 55.94  ? 98  TYR I C   1 
ATOM   8626  O O   . TYR E 1 95  ? -20.951 37.362  -16.737  1.00 49.98  ? 98  TYR I O   1 
ATOM   8627  C CB  . TYR E 1 95  ? -21.726 39.898  -15.264  1.00 50.97  ? 98  TYR I CB  1 
ATOM   8628  C CG  . TYR E 1 95  ? -21.335 39.951  -13.807  1.00 54.76  ? 98  TYR I CG  1 
ATOM   8629  C CD1 . TYR E 1 95  ? -21.192 38.786  -13.066  1.00 47.53  ? 98  TYR I CD1 1 
ATOM   8630  C CD2 . TYR E 1 95  ? -21.085 41.165  -13.177  1.00 41.77  ? 98  TYR I CD2 1 
ATOM   8631  C CE1 . TYR E 1 95  ? -20.823 38.825  -11.735  1.00 44.63  ? 98  TYR I CE1 1 
ATOM   8632  C CE2 . TYR E 1 95  ? -20.715 41.215  -11.843  1.00 46.00  ? 98  TYR I CE2 1 
ATOM   8633  C CZ  . TYR E 1 95  ? -20.587 40.040  -11.128  1.00 50.12  ? 98  TYR I CZ  1 
ATOM   8634  O OH  . TYR E 1 95  ? -20.220 40.076  -9.804   1.00 44.54  ? 98  TYR I OH  1 
ATOM   8635  N N   . PRO E 1 96  ? -19.050 37.768  -15.618  1.00 50.49  ? 99  PRO I N   1 
ATOM   8636  C CA  . PRO E 1 96  ? -18.608 36.374  -15.744  1.00 38.61  ? 99  PRO I CA  1 
ATOM   8637  C C   . PRO E 1 96  ? -19.556 35.401  -15.056  1.00 35.80  ? 99  PRO I C   1 
ATOM   8638  O O   . PRO E 1 96  ? -20.244 35.738  -14.088  1.00 42.86  ? 99  PRO I O   1 
ATOM   8639  C CB  . PRO E 1 96  ? -17.227 36.379  -15.078  1.00 44.38  ? 99  PRO I CB  1 
ATOM   8640  C CG  . PRO E 1 96  ? -17.271 37.536  -14.130  1.00 45.20  ? 99  PRO I CG  1 
ATOM   8641  C CD  . PRO E 1 96  ? -18.127 38.574  -14.799  1.00 48.94  ? 99  PRO I CD  1 
ATOM   8642  N N   . GLY E 1 97  ? -19.592 34.180  -15.581  1.00 42.03  ? 100 GLY I N   1 
ATOM   8643  C CA  . GLY E 1 97  ? -20.456 33.143  -15.057  1.00 37.00  ? 100 GLY I CA  1 
ATOM   8644  C C   . GLY E 1 97  ? -20.760 32.080  -16.092  1.00 42.46  ? 100 GLY I C   1 
ATOM   8645  O O   . GLY E 1 97  ? -19.859 31.636  -16.810  1.00 53.85  ? 100 GLY I O   1 
ATOM   8646  N N   . SER E 1 98  ? -22.021 31.664  -16.187  1.00 48.07  ? 101 SER I N   1 
ATOM   8647  C CA  . SER E 1 98  ? -22.394 30.616  -17.126  1.00 43.61  ? 101 SER I CA  1 
ATOM   8648  C C   . SER E 1 98  ? -23.886 30.688  -17.398  1.00 50.82  ? 101 SER I C   1 
ATOM   8649  O O   . SER E 1 98  ? -24.649 31.295  -16.641  1.00 45.72  ? 101 SER I O   1 
ATOM   8650  C CB  . SER E 1 98  ? -22.029 29.226  -16.595  1.00 52.75  ? 101 SER I CB  1 
ATOM   8651  O OG  . SER E 1 98  ? -22.898 28.850  -15.538  1.00 51.45  ? 101 SER I OG  1 
ATOM   8652  N N   . LEU E 1 99  ? -24.287 30.055  -18.498  1.00 53.02  ? 102 LEU I N   1 
ATOM   8653  C CA  . LEU E 1 99  ? -25.687 29.828  -18.833  1.00 40.27  ? 102 LEU I CA  1 
ATOM   8654  C C   . LEU E 1 99  ? -25.908 28.323  -18.896  1.00 51.15  ? 102 LEU I C   1 
ATOM   8655  O O   . LEU E 1 99  ? -25.254 27.630  -19.682  1.00 49.69  ? 102 LEU I O   1 
ATOM   8656  C CB  . LEU E 1 99  ? -26.052 30.497  -20.162  1.00 43.65  ? 102 LEU I CB  1 
ATOM   8657  C CG  . LEU E 1 99  ? -27.465 30.274  -20.707  1.00 48.58  ? 102 LEU I CG  1 
ATOM   8658  C CD1 . LEU E 1 99  ? -28.515 30.608  -19.658  1.00 48.79  ? 102 LEU I CD1 1 
ATOM   8659  C CD2 . LEU E 1 99  ? -27.684 31.107  -21.959  1.00 45.80  ? 102 LEU I CD2 1 
ATOM   8660  N N   . ASN E 1 100 ? -26.820 27.824  -18.065  1.00 40.31  ? 103 ASN I N   1 
ATOM   8661  C CA  . ASN E 1 100 ? -27.025 26.387  -17.932  1.00 47.91  ? 103 ASN I CA  1 
ATOM   8662  C C   . ASN E 1 100 ? -27.642 25.795  -19.197  1.00 44.88  ? 103 ASN I C   1 
ATOM   8663  O O   . ASN E 1 100 ? -28.466 26.431  -19.860  1.00 45.24  ? 103 ASN I O   1 
ATOM   8664  C CB  . ASN E 1 100 ? -27.916 26.102  -16.723  1.00 45.34  ? 103 ASN I CB  1 
ATOM   8665  C CG  . ASN E 1 100 ? -28.076 24.622  -16.446  1.00 52.01  ? 103 ASN I CG  1 
ATOM   8666  O OD1 . ASN E 1 100 ? -29.169 24.069  -16.573  1.00 59.24  ? 103 ASN I OD1 1 
ATOM   8667  N ND2 . ASN E 1 100 ? -26.983 23.969  -16.068  1.00 47.78  ? 103 ASN I ND2 1 
ATOM   8668  N N   . ASP E 1 101 ? -27.231 24.567  -19.527  1.00 43.50  ? 104 ASP I N   1 
ATOM   8669  C CA  . ASP E 1 101 ? -27.734 23.847  -20.703  1.00 54.82  ? 104 ASP I CA  1 
ATOM   8670  C C   . ASP E 1 101 ? -27.601 24.694  -21.966  1.00 42.49  ? 104 ASP I C   1 
ATOM   8671  O O   . ASP E 1 101 ? -28.510 24.762  -22.796  1.00 50.27  ? 104 ASP I O   1 
ATOM   8672  C CB  . ASP E 1 101 ? -29.183 23.398  -20.500  1.00 62.41  ? 104 ASP I CB  1 
ATOM   8673  C CG  . ASP E 1 101 ? -29.289 22.089  -19.741  1.00 73.48  ? 104 ASP I CG  1 
ATOM   8674  O OD1 . ASP E 1 101 ? -28.423 21.212  -19.944  1.00 76.70  ? 104 ASP I OD1 1 
ATOM   8675  O OD2 . ASP E 1 101 ? -30.240 21.935  -18.945  1.00 74.25  ? 104 ASP I OD2 1 
ATOM   8676  N N   . TYR E 1 102 ? -26.445 25.347  -22.105  1.00 51.21  ? 105 TYR I N   1 
ATOM   8677  C CA  . TYR E 1 102 ? -26.256 26.333  -23.164  1.00 40.13  ? 105 TYR I CA  1 
ATOM   8678  C C   . TYR E 1 102 ? -26.342 25.702  -24.549  1.00 48.60  ? 105 TYR I C   1 
ATOM   8679  O O   . TYR E 1 102 ? -26.979 26.256  -25.452  1.00 50.99  ? 105 TYR I O   1 
ATOM   8680  C CB  . TYR E 1 102 ? -24.912 27.034  -22.968  1.00 47.51  ? 105 TYR I CB  1 
ATOM   8681  C CG  . TYR E 1 102 ? -24.663 28.205  -23.887  1.00 56.40  ? 105 TYR I CG  1 
ATOM   8682  C CD1 . TYR E 1 102 ? -25.672 29.114  -24.180  1.00 53.19  ? 105 TYR I CD1 1 
ATOM   8683  C CD2 . TYR E 1 102 ? -23.407 28.418  -24.441  1.00 47.00  ? 105 TYR I CD2 1 
ATOM   8684  C CE1 . TYR E 1 102 ? -25.440 30.192  -25.013  1.00 51.49  ? 105 TYR I CE1 1 
ATOM   8685  C CE2 . TYR E 1 102 ? -23.165 29.494  -25.271  1.00 48.53  ? 105 TYR I CE2 1 
ATOM   8686  C CZ  . TYR E 1 102 ? -24.184 30.378  -25.554  1.00 56.49  ? 105 TYR I CZ  1 
ATOM   8687  O OH  . TYR E 1 102 ? -23.943 31.449  -26.382  1.00 64.14  ? 105 TYR I OH  1 
ATOM   8688  N N   . GLU E 1 103 ? -25.712 24.540  -24.736  1.00 42.97  ? 106 GLU I N   1 
ATOM   8689  C CA  . GLU E 1 103 ? -25.647 23.946  -26.068  1.00 48.66  ? 106 GLU I CA  1 
ATOM   8690  C C   . GLU E 1 103 ? -27.006 23.416  -26.511  1.00 53.25  ? 106 GLU I C   1 
ATOM   8691  O O   . GLU E 1 103 ? -27.370 23.539  -27.687  1.00 43.55  ? 106 GLU I O   1 
ATOM   8692  C CB  . GLU E 1 103 ? -24.594 22.840  -26.101  1.00 48.59  ? 106 GLU I CB  1 
ATOM   8693  C CG  . GLU E 1 103 ? -23.165 23.335  -25.899  1.00 48.13  ? 106 GLU I CG  1 
ATOM   8694  C CD  . GLU E 1 103 ? -22.850 23.643  -24.445  1.00 69.66  ? 106 GLU I CD  1 
ATOM   8695  O OE1 . GLU E 1 103 ? -23.632 23.222  -23.563  1.00 60.03  ? 106 GLU I OE1 1 
ATOM   8696  O OE2 . GLU E 1 103 ? -21.825 24.310  -24.186  1.00 81.31  ? 106 GLU I OE2 1 
ATOM   8697  N N   . GLU E 1 104 ? -27.767 22.818  -25.589  1.00 47.12  ? 107 GLU I N   1 
ATOM   8698  C CA  . GLU E 1 104 ? -29.135 22.424  -25.910  1.00 45.36  ? 107 GLU I CA  1 
ATOM   8699  C C   . GLU E 1 104 ? -29.987 23.641  -26.243  1.00 41.66  ? 107 GLU I C   1 
ATOM   8700  O O   . GLU E 1 104 ? -30.816 23.596  -27.160  1.00 49.85  ? 107 GLU I O   1 
ATOM   8701  C CB  . GLU E 1 104 ? -29.753 21.641  -24.749  1.00 38.36  ? 107 GLU I CB  1 
ATOM   8702  C CG  . GLU E 1 104 ? -29.269 20.200  -24.627  1.00 45.89  ? 107 GLU I CG  1 
ATOM   8703  C CD  . GLU E 1 104 ? -29.665 19.336  -25.816  1.00 47.98  ? 107 GLU I CD  1 
ATOM   8704  O OE1 . GLU E 1 104 ? -28.760 18.788  -26.480  1.00 46.57  ? 107 GLU I OE1 1 
ATOM   8705  O OE2 . GLU E 1 104 ? -30.880 19.199  -26.084  1.00 51.08  ? 107 GLU I OE2 1 
ATOM   8706  N N   . LEU E 1 105 ? -29.804 24.737  -25.500  1.00 44.12  ? 108 LEU I N   1 
ATOM   8707  C CA  . LEU E 1 105 ? -30.526 25.969  -25.801  1.00 47.48  ? 108 LEU I CA  1 
ATOM   8708  C C   . LEU E 1 105 ? -30.146 26.513  -27.174  1.00 46.72  ? 108 LEU I C   1 
ATOM   8709  O O   . LEU E 1 105 ? -31.015 26.958  -27.933  1.00 50.74  ? 108 LEU I O   1 
ATOM   8710  C CB  . LEU E 1 105 ? -30.257 27.011  -24.715  1.00 45.22  ? 108 LEU I CB  1 
ATOM   8711  C CG  . LEU E 1 105 ? -30.888 28.393  -24.896  1.00 58.15  ? 108 LEU I CG  1 
ATOM   8712  C CD1 . LEU E 1 105 ? -32.402 28.286  -25.029  1.00 42.69  ? 108 LEU I CD1 1 
ATOM   8713  C CD2 . LEU E 1 105 ? -30.513 29.300  -23.734  1.00 44.62  ? 108 LEU I CD2 1 
ATOM   8714  N N   . LYS E 1 106 ? -28.852 26.491  -27.508  1.00 48.02  ? 109 LYS I N   1 
ATOM   8715  C CA  . LYS E 1 106 ? -28.414 26.956  -28.822  1.00 36.66  ? 109 LYS I CA  1 
ATOM   8716  C C   . LYS E 1 106 ? -28.991 26.090  -29.934  1.00 56.96  ? 109 LYS I C   1 
ATOM   8717  O O   . LYS E 1 106 ? -29.425 26.605  -30.971  1.00 43.60  ? 109 LYS I O   1 
ATOM   8718  C CB  . LYS E 1 106 ? -26.887 26.965  -28.895  1.00 50.36  ? 109 LYS I CB  1 
ATOM   8719  C CG  . LYS E 1 106 ? -26.227 28.046  -28.061  1.00 57.84  ? 109 LYS I CG  1 
ATOM   8720  C CD  . LYS E 1 106 ? -24.836 27.619  -27.618  1.00 56.48  ? 109 LYS I CD  1 
ATOM   8721  C CE  . LYS E 1 106 ? -23.884 27.487  -28.791  1.00 57.60  ? 109 LYS I CE  1 
ATOM   8722  N NZ  . LYS E 1 106 ? -23.632 28.800  -29.443  1.00 75.15  ? 109 LYS I NZ  1 
ATOM   8723  N N   . HIS E 1 107 ? -28.995 24.770  -29.738  1.00 49.19  ? 110 HIS I N   1 
ATOM   8724  C CA  . HIS E 1 107 ? -29.552 23.874  -30.744  1.00 52.32  ? 110 HIS I CA  1 
ATOM   8725  C C   . HIS E 1 107 ? -31.040 24.132  -30.943  1.00 54.31  ? 110 HIS I C   1 
ATOM   8726  O O   . HIS E 1 107 ? -31.541 24.090  -32.072  1.00 53.85  ? 110 HIS I O   1 
ATOM   8727  C CB  . HIS E 1 107 ? -29.306 22.419  -30.340  1.00 49.85  ? 110 HIS I CB  1 
ATOM   8728  C CG  . HIS E 1 107 ? -29.778 21.419  -31.350  1.00 47.29  ? 110 HIS I CG  1 
ATOM   8729  N ND1 . HIS E 1 107 ? -29.121 21.197  -32.541  1.00 60.95  ? 110 HIS I ND1 1 
ATOM   8730  C CD2 . HIS E 1 107 ? -30.842 20.580  -31.345  1.00 48.70  ? 110 HIS I CD2 1 
ATOM   8731  C CE1 . HIS E 1 107 ? -29.759 20.264  -33.226  1.00 58.64  ? 110 HIS I CE1 1 
ATOM   8732  N NE2 . HIS E 1 107 ? -30.807 19.873  -32.522  1.00 53.76  ? 110 HIS I NE2 1 
ATOM   8733  N N   . MET E 1 108 ? -31.760 24.404  -29.853  1.00 49.57  ? 111 MET I N   1 
ATOM   8734  C CA  . MET E 1 108 ? -33.200 24.613  -29.948  1.00 53.31  ? 111 MET I CA  1 
ATOM   8735  C C   . MET E 1 108 ? -33.537 25.925  -30.646  1.00 59.24  ? 111 MET I C   1 
ATOM   8736  O O   . MET E 1 108 ? -34.575 26.023  -31.311  1.00 61.81  ? 111 MET I O   1 
ATOM   8737  C CB  . MET E 1 108 ? -33.822 24.568  -28.553  1.00 53.09  ? 111 MET I CB  1 
ATOM   8738  C CG  . MET E 1 108 ? -35.336 24.520  -28.557  1.00 60.72  ? 111 MET I CG  1 
ATOM   8739  S SD  . MET E 1 108 ? -36.063 26.046  -27.944  1.00 86.37  ? 111 MET I SD  1 
ATOM   8740  C CE  . MET E 1 108 ? -35.677 25.915  -26.201  1.00 54.81  ? 111 MET I CE  1 
ATOM   8741  N N   . LEU E 1 109 ? -32.681 26.935  -30.518  1.00 55.43  ? 112 LEU I N   1 
ATOM   8742  C CA  . LEU E 1 109 ? -32.905 28.234  -31.137  1.00 50.83  ? 112 LEU I CA  1 
ATOM   8743  C C   . LEU E 1 109 ? -32.325 28.336  -32.541  1.00 55.35  ? 112 LEU I C   1 
ATOM   8744  O O   . LEU E 1 109 ? -32.403 29.409  -33.148  1.00 59.30  ? 112 LEU I O   1 
ATOM   8745  C CB  . LEU E 1 109 ? -32.310 29.342  -30.265  1.00 50.17  ? 112 LEU I CB  1 
ATOM   8746  C CG  . LEU E 1 109 ? -32.934 29.529  -28.883  1.00 52.78  ? 112 LEU I CG  1 
ATOM   8747  C CD1 . LEU E 1 109 ? -32.075 30.455  -28.051  1.00 50.46  ? 112 LEU I CD1 1 
ATOM   8748  C CD2 . LEU E 1 109 ? -34.349 30.071  -29.005  1.00 49.28  ? 112 LEU I CD2 1 
ATOM   8749  N N   . SER E 1 110 ? -31.748 27.253  -33.070  1.00 50.10  ? 113 SER I N   1 
ATOM   8750  C CA  . SER E 1 110 ? -31.076 27.328  -34.364  1.00 55.24  ? 113 SER I CA  1 
ATOM   8751  C C   . SER E 1 110 ? -32.050 27.700  -35.478  1.00 56.11  ? 113 SER I C   1 
ATOM   8752  O O   . SER E 1 110 ? -31.715 28.498  -36.361  1.00 59.39  ? 113 SER I O   1 
ATOM   8753  C CB  . SER E 1 110 ? -30.378 26.003  -34.671  1.00 49.77  ? 113 SER I CB  1 
ATOM   8754  O OG  . SER E 1 110 ? -31.291 24.919  -34.641  1.00 55.94  ? 113 SER I OG  1 
ATOM   8755  N N   . ARG E 1 111 ? -33.256 27.138  -35.456  1.00 53.50  ? 114 ARG I N   1 
ATOM   8756  C CA  . ARG E 1 111 ? -34.296 27.468  -36.425  1.00 61.08  ? 114 ARG I CA  1 
ATOM   8757  C C   . ARG E 1 111 ? -35.593 27.726  -35.675  1.00 64.94  ? 114 ARG I C   1 
ATOM   8758  O O   . ARG E 1 111 ? -36.091 26.840  -34.972  1.00 65.43  ? 114 ARG I O   1 
ATOM   8759  C CB  . ARG E 1 111 ? -34.482 26.345  -37.448  1.00 57.15  ? 114 ARG I CB  1 
ATOM   8760  C CG  . ARG E 1 111 ? -35.588 26.612  -38.452  1.00 63.50  ? 114 ARG I CG  1 
ATOM   8761  C CD  . ARG E 1 111 ? -35.937 25.363  -39.242  1.00 66.24  ? 114 ARG I CD  1 
ATOM   8762  N NE  . ARG E 1 111 ? -35.246 25.298  -40.524  1.00 87.71  ? 114 ARG I NE  1 
ATOM   8763  C CZ  . ARG E 1 111 ? -35.395 24.315  -41.403  1.00 96.38  ? 114 ARG I CZ  1 
ATOM   8764  N NH1 . ARG E 1 111 ? -36.191 23.286  -41.161  1.00 78.44  ? 114 ARG I NH1 1 
ATOM   8765  N NH2 . ARG E 1 111 ? -34.730 24.368  -42.555  1.00 95.67  ? 114 ARG I NH2 1 
ATOM   8766  N N   . ILE E 1 112 ? -36.143 28.928  -35.833  1.00 58.34  ? 115 ILE I N   1 
ATOM   8767  C CA  . ILE E 1 112 ? -37.316 29.365  -35.086  1.00 65.06  ? 115 ILE I CA  1 
ATOM   8768  C C   . ILE E 1 112 ? -38.336 29.943  -36.058  1.00 65.65  ? 115 ILE I C   1 
ATOM   8769  O O   . ILE E 1 112 ? -37.984 30.746  -36.930  1.00 66.45  ? 115 ILE I O   1 
ATOM   8770  C CB  . ILE E 1 112 ? -36.943 30.394  -34.002  1.00 56.93  ? 115 ILE I CB  1 
ATOM   8771  C CG1 . ILE E 1 112 ? -36.102 29.725  -32.914  1.00 56.58  ? 115 ILE I CG1 1 
ATOM   8772  C CG2 . ILE E 1 112 ? -38.185 31.031  -33.403  1.00 67.93  ? 115 ILE I CG2 1 
ATOM   8773  C CD1 . ILE E 1 112 ? -36.759 28.512  -32.299  1.00 59.23  ? 115 ILE I CD1 1 
ATOM   8774  N N   . ASN E 1 113 ? -39.598 29.530  -35.909  1.00 68.48  ? 116 ASN I N   1 
ATOM   8775  C CA  . ASN E 1 113 ? -40.657 30.005  -36.793  1.00 65.51  ? 116 ASN I CA  1 
ATOM   8776  C C   . ASN E 1 113 ? -41.207 31.356  -36.344  1.00 70.10  ? 116 ASN I C   1 
ATOM   8777  O O   . ASN E 1 113 ? -41.499 32.215  -37.183  1.00 74.05  ? 116 ASN I O   1 
ATOM   8778  C CB  . ASN E 1 113 ? -41.775 28.962  -36.872  1.00 67.12  ? 116 ASN I CB  1 
ATOM   8779  C CG  . ASN E 1 113 ? -42.913 29.389  -37.780  1.00 75.06  ? 116 ASN I CG  1 
ATOM   8780  O OD1 . ASN E 1 113 ? -44.071 29.043  -37.546  1.00 75.75  ? 116 ASN I OD1 1 
ATOM   8781  N ND2 . ASN E 1 113 ? -42.588 30.147  -38.822  1.00 82.70  ? 116 ASN I ND2 1 
ATOM   8782  N N   . HIS E 1 114 ? -41.359 31.565  -35.037  1.00 62.89  ? 117 HIS I N   1 
ATOM   8783  C CA  . HIS E 1 114 ? -41.797 32.853  -34.513  1.00 64.70  ? 117 HIS I CA  1 
ATOM   8784  C C   . HIS E 1 114 ? -41.052 33.155  -33.222  1.00 67.68  ? 117 HIS I C   1 
ATOM   8785  O O   . HIS E 1 114 ? -41.004 32.315  -32.320  1.00 58.40  ? 117 HIS I O   1 
ATOM   8786  C CB  . HIS E 1 114 ? -43.309 32.882  -34.268  1.00 75.63  ? 117 HIS I CB  1 
ATOM   8787  C CG  . HIS E 1 114 ? -43.819 34.220  -33.832  1.00 74.43  ? 117 HIS I CG  1 
ATOM   8788  N ND1 . HIS E 1 114 ? -44.589 34.392  -32.702  1.00 87.91  ? 117 HIS I ND1 1 
ATOM   8789  C CD2 . HIS E 1 114 ? -43.656 35.453  -34.368  1.00 73.70  ? 117 HIS I CD2 1 
ATOM   8790  C CE1 . HIS E 1 114 ? -44.886 35.673  -32.566  1.00 85.60  ? 117 HIS I CE1 1 
ATOM   8791  N NE2 . HIS E 1 114 ? -44.331 36.337  -33.563  1.00 75.99  ? 117 HIS I NE2 1 
ATOM   8792  N N   . PHE E 1 115 ? -40.488 34.358  -33.136  1.00 69.56  ? 118 PHE I N   1 
ATOM   8793  C CA  . PHE E 1 115 ? -39.692 34.778  -31.987  1.00 70.57  ? 118 PHE I CA  1 
ATOM   8794  C C   . PHE E 1 115 ? -40.060 36.215  -31.655  1.00 65.62  ? 118 PHE I C   1 
ATOM   8795  O O   . PHE E 1 115 ? -39.833 37.115  -32.469  1.00 76.68  ? 118 PHE I O   1 
ATOM   8796  C CB  . PHE E 1 115 ? -38.196 34.654  -32.287  1.00 62.35  ? 118 PHE I CB  1 
ATOM   8797  C CG  . PHE E 1 115 ? -37.318 34.718  -31.071  1.00 58.71  ? 118 PHE I CG  1 
ATOM   8798  C CD1 . PHE E 1 115 ? -37.177 33.615  -30.244  1.00 65.86  ? 118 PHE I CD1 1 
ATOM   8799  C CD2 . PHE E 1 115 ? -36.614 35.872  -30.767  1.00 66.44  ? 118 PHE I CD2 1 
ATOM   8800  C CE1 . PHE E 1 115 ? -36.361 33.665  -29.128  1.00 56.93  ? 118 PHE I CE1 1 
ATOM   8801  C CE2 . PHE E 1 115 ? -35.795 35.929  -29.654  1.00 58.19  ? 118 PHE I CE2 1 
ATOM   8802  C CZ  . PHE E 1 115 ? -35.667 34.823  -28.834  1.00 57.83  ? 118 PHE I CZ  1 
ATOM   8803  N N   . GLU E 1 116 ? -40.624 36.431  -30.468  1.00 62.16  ? 119 GLU I N   1 
ATOM   8804  C CA  . GLU E 1 116 ? -41.145 37.739  -30.084  1.00 65.25  ? 119 GLU I CA  1 
ATOM   8805  C C   . GLU E 1 116 ? -40.763 38.029  -28.641  1.00 64.50  ? 119 GLU I C   1 
ATOM   8806  O O   . GLU E 1 116 ? -41.097 37.250  -27.744  1.00 64.06  ? 119 GLU I O   1 
ATOM   8807  C CB  . GLU E 1 116 ? -42.667 37.791  -30.251  1.00 66.00  ? 119 GLU I CB  1 
ATOM   8808  C CG  . GLU E 1 116 ? -43.221 39.198  -30.362  1.00 76.99  ? 119 GLU I CG  1 
ATOM   8809  C CD  . GLU E 1 116 ? -44.648 39.321  -29.879  1.00 94.76  ? 119 GLU I CD  1 
ATOM   8810  O OE1 . GLU E 1 116 ? -45.395 38.326  -29.963  1.00 100.36 ? 119 GLU I OE1 1 
ATOM   8811  O OE2 . GLU E 1 116 ? -45.017 40.418  -29.407  1.00 85.81  ? 119 GLU I OE2 1 
ATOM   8812  N N   . LYS E 1 117 ? -40.079 39.148  -28.411  1.00 56.93  ? 120 LYS I N   1 
ATOM   8813  C CA  . LYS E 1 117 ? -39.737 39.564  -27.058  1.00 56.55  ? 120 LYS I CA  1 
ATOM   8814  C C   . LYS E 1 117 ? -40.888 40.359  -26.455  1.00 70.44  ? 120 LYS I C   1 
ATOM   8815  O O   . LYS E 1 117 ? -41.431 41.263  -27.097  1.00 79.02  ? 120 LYS I O   1 
ATOM   8816  C CB  . LYS E 1 117 ? -38.456 40.399  -27.039  1.00 56.66  ? 120 LYS I CB  1 
ATOM   8817  C CG  . LYS E 1 117 ? -38.040 40.823  -25.631  1.00 64.77  ? 120 LYS I CG  1 
ATOM   8818  C CD  . LYS E 1 117 ? -36.598 41.309  -25.566  1.00 70.23  ? 120 LYS I CD  1 
ATOM   8819  C CE  . LYS E 1 117 ? -36.492 42.806  -25.791  1.00 72.90  ? 120 LYS I CE  1 
ATOM   8820  N NZ  . LYS E 1 117 ? -35.113 43.297  -25.518  1.00 81.19  ? 120 LYS I NZ  1 
ATOM   8821  N N   . ILE E 1 118 ? -41.259 40.013  -25.221  1.00 58.05  ? 121 ILE I N   1 
ATOM   8822  C CA  . ILE E 1 118 ? -42.310 40.704  -24.488  1.00 60.44  ? 121 ILE I CA  1 
ATOM   8823  C C   . ILE E 1 118 ? -41.829 40.960  -23.067  1.00 67.41  ? 121 ILE I C   1 
ATOM   8824  O O   . ILE E 1 118 ? -40.940 40.280  -22.552  1.00 71.23  ? 121 ILE I O   1 
ATOM   8825  C CB  . ILE E 1 118 ? -43.634 39.912  -24.457  1.00 68.30  ? 121 ILE I CB  1 
ATOM   8826  C CG1 . ILE E 1 118 ? -43.441 38.584  -23.720  1.00 67.02  ? 121 ILE I CG1 1 
ATOM   8827  C CG2 . ILE E 1 118 ? -44.154 39.686  -25.865  1.00 63.50  ? 121 ILE I CG2 1 
ATOM   8828  C CD1 . ILE E 1 118 ? -44.725 37.822  -23.473  1.00 74.47  ? 121 ILE I CD1 1 
ATOM   8829  N N   . GLN E 1 119 ? -42.440 41.955  -22.432  1.00 68.38  ? 122 GLN I N   1 
ATOM   8830  C CA  . GLN E 1 119 ? -42.168 42.268  -21.037  1.00 70.55  ? 122 GLN I CA  1 
ATOM   8831  C C   . GLN E 1 119 ? -43.154 41.505  -20.162  1.00 73.80  ? 122 GLN I C   1 
ATOM   8832  O O   . GLN E 1 119 ? -44.370 41.628  -20.339  1.00 73.69  ? 122 GLN I O   1 
ATOM   8833  C CB  . GLN E 1 119 ? -42.275 43.772  -20.792  1.00 76.10  ? 122 GLN I CB  1 
ATOM   8834  C CG  . GLN E 1 119 ? -42.104 44.179  -19.339  1.00 74.20  ? 122 GLN I CG  1 
ATOM   8835  C CD  . GLN E 1 119 ? -42.293 45.668  -19.128  1.00 70.10  ? 122 GLN I CD  1 
ATOM   8836  O OE1 . GLN E 1 119 ? -43.406 46.136  -18.888  1.00 89.88  ? 122 GLN I OE1 1 
ATOM   8837  N NE2 . GLN E 1 119 ? -41.204 46.422  -19.218  1.00 64.97  ? 122 GLN I NE2 1 
ATOM   8838  N N   . ILE E 1 120 ? -42.632 40.714  -19.224  1.00 73.31  ? 123 ILE I N   1 
ATOM   8839  C CA  . ILE E 1 120 ? -43.473 39.926  -18.341  1.00 64.80  ? 123 ILE I CA  1 
ATOM   8840  C C   . ILE E 1 120 ? -43.442 40.427  -16.901  1.00 61.36  ? 123 ILE I C   1 
ATOM   8841  O O   . ILE E 1 120 ? -44.431 40.253  -16.179  1.00 73.80  ? 123 ILE I O   1 
ATOM   8842  C CB  . ILE E 1 120 ? -43.093 38.431  -18.404  1.00 66.99  ? 123 ILE I CB  1 
ATOM   8843  C CG1 . ILE E 1 120 ? -41.673 38.208  -17.875  1.00 55.27  ? 123 ILE I CG1 1 
ATOM   8844  C CG2 . ILE E 1 120 ? -43.224 37.910  -19.825  1.00 65.09  ? 123 ILE I CG2 1 
ATOM   8845  C CD1 . ILE E 1 120 ? -41.289 36.751  -17.755  1.00 56.11  ? 123 ILE I CD1 1 
ATOM   8846  N N   . ILE E 1 121 ? -42.343 41.031  -16.458  1.00 68.70  ? 124 ILE I N   1 
ATOM   8847  C CA  . ILE E 1 121 ? -42.243 41.592  -15.112  1.00 62.86  ? 124 ILE I CA  1 
ATOM   8848  C C   . ILE E 1 121 ? -41.576 42.958  -15.215  1.00 66.93  ? 124 ILE I C   1 
ATOM   8849  O O   . ILE E 1 121 ? -40.338 43.040  -15.232  1.00 77.67  ? 124 ILE I O   1 
ATOM   8850  C CB  . ILE E 1 121 ? -41.460 40.669  -14.163  1.00 62.24  ? 124 ILE I CB  1 
ATOM   8851  C CG1 . ILE E 1 121 ? -42.057 39.260  -14.149  1.00 67.23  ? 124 ILE I CG1 1 
ATOM   8852  C CG2 . ILE E 1 121 ? -41.458 41.240  -12.750  1.00 61.48  ? 124 ILE I CG2 1 
ATOM   8853  C CD1 . ILE E 1 121 ? -41.272 38.275  -13.311  1.00 59.94  ? 124 ILE I CD1 1 
ATOM   8854  N N   . PRO E 1 122 ? -42.339 44.046  -15.296  1.00 77.63  ? 125 PRO I N   1 
ATOM   8855  C CA  . PRO E 1 122 ? -41.719 45.371  -15.386  1.00 77.83  ? 125 PRO I CA  1 
ATOM   8856  C C   . PRO E 1 122 ? -40.989 45.731  -14.103  1.00 72.87  ? 125 PRO I C   1 
ATOM   8857  O O   . PRO E 1 122 ? -41.309 45.238  -13.018  1.00 78.96  ? 125 PRO I O   1 
ATOM   8858  C CB  . PRO E 1 122 ? -42.910 46.305  -15.630  1.00 77.88  ? 125 PRO I CB  1 
ATOM   8859  C CG  . PRO E 1 122 ? -44.077 45.579  -15.051  1.00 72.77  ? 125 PRO I CG  1 
ATOM   8860  C CD  . PRO E 1 122 ? -43.810 44.119  -15.297  1.00 72.64  ? 125 PRO I CD  1 
ATOM   8861  N N   . LYS E 1 123 A -39.998 46.615  -14.240  1.00 77.42  ? 125 LYS I N   1 
ATOM   8862  C CA  . LYS E 1 123 A -39.208 47.055  -13.095  1.00 79.15  ? 125 LYS I CA  1 
ATOM   8863  C C   . LYS E 1 123 A -40.054 47.730  -12.023  1.00 74.45  ? 125 LYS I C   1 
ATOM   8864  O O   . LYS E 1 123 A -39.575 47.900  -10.896  1.00 77.36  ? 125 LYS I O   1 
ATOM   8865  C CB  . LYS E 1 123 A -38.095 47.999  -13.560  1.00 82.93  ? 125 LYS I CB  1 
ATOM   8866  C CG  . LYS E 1 123 A -36.870 47.279  -14.107  1.00 85.93  ? 125 LYS I CG  1 
ATOM   8867  C CD  . LYS E 1 123 A -36.030 48.180  -15.002  1.00 84.80  ? 125 LYS I CD  1 
ATOM   8868  C CE  . LYS E 1 123 A -36.809 48.603  -16.240  1.00 90.99  ? 125 LYS I CE  1 
ATOM   8869  N NZ  . LYS E 1 123 A -35.921 48.823  -17.416  1.00 72.37  ? 125 LYS I NZ  1 
ATOM   8870  N N   . SER E 1 124 B -41.289 48.123  -12.345  1.00 81.97  ? 125 SER I N   1 
ATOM   8871  C CA  . SER E 1 124 B -42.193 48.673  -11.343  1.00 77.83  ? 125 SER I CA  1 
ATOM   8872  C C   . SER E 1 124 B -42.707 47.613  -10.377  1.00 74.78  ? 125 SER I C   1 
ATOM   8873  O O   . SER E 1 124 B -43.216 47.964  -9.308   1.00 83.18  ? 125 SER I O   1 
ATOM   8874  C CB  . SER E 1 124 B -43.378 49.359  -12.026  1.00 90.37  ? 125 SER I CB  1 
ATOM   8875  O OG  . SER E 1 124 B -44.197 48.413  -12.693  1.00 89.80  ? 125 SER I OG  1 
ATOM   8876  N N   . SER E 1 125 ? -42.585 46.331  -10.724  1.00 73.38  ? 126 SER I N   1 
ATOM   8877  C CA  . SER E 1 125 ? -43.130 45.244  -9.921   1.00 67.75  ? 126 SER I CA  1 
ATOM   8878  C C   . SER E 1 125 ? -42.218 44.829  -8.771   1.00 66.59  ? 126 SER I C   1 
ATOM   8879  O O   . SER E 1 125 ? -42.391 43.729  -8.231   1.00 70.16  ? 126 SER I O   1 
ATOM   8880  C CB  . SER E 1 125 ? -43.425 44.033  -10.810  1.00 71.68  ? 126 SER I CB  1 
ATOM   8881  O OG  . SER E 1 125 ? -44.193 44.405  -11.941  1.00 85.04  ? 126 SER I OG  1 
ATOM   8882  N N   . TRP E 1 126 ? -41.261 45.669  -8.383   1.00 61.96  ? 127 TRP I N   1 
ATOM   8883  C CA  . TRP E 1 126 ? -40.352 45.385  -7.272   1.00 74.22  ? 127 TRP I CA  1 
ATOM   8884  C C   . TRP E 1 126 ? -40.362 46.571  -6.315   1.00 67.66  ? 127 TRP I C   1 
ATOM   8885  O O   . TRP E 1 126 ? -39.356 47.274  -6.159   1.00 69.49  ? 127 TRP I O   1 
ATOM   8886  C CB  . TRP E 1 126 ? -38.937 45.098  -7.777   1.00 58.19  ? 127 TRP I CB  1 
ATOM   8887  C CG  . TRP E 1 126 ? -38.875 44.073  -8.869   1.00 55.36  ? 127 TRP I CG  1 
ATOM   8888  C CD1 . TRP E 1 126 ? -38.697 44.304  -10.203  1.00 58.67  ? 127 TRP I CD1 1 
ATOM   8889  C CD2 . TRP E 1 126 ? -38.992 42.654  -8.720   1.00 59.40  ? 127 TRP I CD2 1 
ATOM   8890  N NE1 . TRP E 1 126 ? -38.695 43.115  -10.893  1.00 61.86  ? 127 TRP I NE1 1 
ATOM   8891  C CE2 . TRP E 1 126 ? -38.875 42.087  -10.005  1.00 58.14  ? 127 TRP I CE2 1 
ATOM   8892  C CE3 . TRP E 1 126 ? -39.184 41.807  -7.625   1.00 59.56  ? 127 TRP I CE3 1 
ATOM   8893  C CZ2 . TRP E 1 126 ? -38.945 40.714  -10.224  1.00 56.82  ? 127 TRP I CZ2 1 
ATOM   8894  C CZ3 . TRP E 1 126 ? -39.253 40.443  -7.844   1.00 62.18  ? 127 TRP I CZ3 1 
ATOM   8895  C CH2 . TRP E 1 126 ? -39.134 39.910  -9.133   1.00 53.71  ? 127 TRP I CH2 1 
ATOM   8896  N N   . PRO E 1 127 ? -41.492 46.815  -5.643   1.00 71.03  ? 128 PRO I N   1 
ATOM   8897  C CA  . PRO E 1 127 ? -41.599 48.020  -4.806   1.00 63.96  ? 128 PRO I CA  1 
ATOM   8898  C C   . PRO E 1 127 ? -40.763 47.967  -3.541   1.00 60.21  ? 128 PRO I C   1 
ATOM   8899  O O   . PRO E 1 127 ? -40.438 49.028  -2.993   1.00 68.86  ? 128 PRO I O   1 
ATOM   8900  C CB  . PRO E 1 127 ? -43.096 48.084  -4.482   1.00 53.19  ? 128 PRO I CB  1 
ATOM   8901  C CG  . PRO E 1 127 ? -43.528 46.654  -4.499   1.00 62.91  ? 128 PRO I CG  1 
ATOM   8902  C CD  . PRO E 1 127 ? -42.700 45.973  -5.559   1.00 65.54  ? 128 PRO I CD  1 
ATOM   8903  N N   . ASN E 1 128 ? -40.407 46.779  -3.056   1.00 58.85  ? 129 ASN I N   1 
ATOM   8904  C CA  . ASN E 1 128 ? -39.655 46.636  -1.818   1.00 60.13  ? 129 ASN I CA  1 
ATOM   8905  C C   . ASN E 1 128 ? -38.173 46.378  -2.050   1.00 66.37  ? 129 ASN I C   1 
ATOM   8906  O O   . ASN E 1 128 ? -37.451 46.076  -1.094   1.00 64.23  ? 129 ASN I O   1 
ATOM   8907  C CB  . ASN E 1 128 ? -40.250 45.511  -0.970   1.00 63.36  ? 129 ASN I CB  1 
ATOM   8908  C CG  . ASN E 1 128 ? -41.736 45.681  -0.744   1.00 66.19  ? 129 ASN I CG  1 
ATOM   8909  O OD1 . ASN E 1 128 ? -42.524 44.769  -1.000   1.00 67.38  ? 129 ASN I OD1 1 
ATOM   8910  N ND2 . ASN E 1 128 ? -42.130 46.857  -0.270   1.00 57.48  ? 129 ASN I ND2 1 
ATOM   8911  N N   . HIS E 1 129 ? -37.700 46.486  -3.290   1.00 61.12  ? 130 HIS I N   1 
ATOM   8912  C CA  . HIS E 1 129 ? -36.310 46.196  -3.602   1.00 68.15  ? 130 HIS I CA  1 
ATOM   8913  C C   . HIS E 1 129 ? -35.759 47.249  -4.550   1.00 60.02  ? 130 HIS I C   1 
ATOM   8914  O O   . HIS E 1 129 ? -36.493 47.841  -5.346   1.00 57.47  ? 130 HIS I O   1 
ATOM   8915  C CB  . HIS E 1 129 ? -36.152 44.798  -4.217   1.00 51.07  ? 130 HIS I CB  1 
ATOM   8916  C CG  . HIS E 1 129 ? -36.568 43.689  -3.302   1.00 56.53  ? 130 HIS I CG  1 
ATOM   8917  N ND1 . HIS E 1 129 ? -37.877 43.275  -3.182   1.00 52.36  ? 130 HIS I ND1 1 
ATOM   8918  C CD2 . HIS E 1 129 ? -35.849 42.917  -2.453   1.00 55.59  ? 130 HIS I CD2 1 
ATOM   8919  C CE1 . HIS E 1 129 ? -37.947 42.293  -2.301   1.00 50.58  ? 130 HIS I CE1 1 
ATOM   8920  N NE2 . HIS E 1 129 ? -36.730 42.055  -1.845   1.00 59.70  ? 130 HIS I NE2 1 
ATOM   8921  N N   . GLU E 1 130 ? -34.451 47.472  -4.453   1.00 60.83  ? 131 GLU I N   1 
ATOM   8922  C CA  . GLU E 1 130 ? -33.759 48.389  -5.346   1.00 57.87  ? 131 GLU I CA  1 
ATOM   8923  C C   . GLU E 1 130 ? -33.577 47.736  -6.712   1.00 59.79  ? 131 GLU I C   1 
ATOM   8924  O O   . GLU E 1 130 ? -33.111 46.597  -6.807   1.00 66.50  ? 131 GLU I O   1 
ATOM   8925  C CB  . GLU E 1 130 ? -32.407 48.779  -4.751   1.00 52.44  ? 131 GLU I CB  1 
ATOM   8926  C CG  . GLU E 1 130 ? -31.636 49.822  -5.547   1.00 80.37  ? 131 GLU I CG  1 
ATOM   8927  C CD  . GLU E 1 130 ? -32.249 51.207  -5.449   1.00 84.22  ? 131 GLU I CD  1 
ATOM   8928  O OE1 . GLU E 1 130 ? -32.657 51.753  -6.497   1.00 79.65  ? 131 GLU I OE1 1 
ATOM   8929  O OE2 . GLU E 1 130 ? -32.324 51.747  -4.324   1.00 78.08  ? 131 GLU I OE2 1 
ATOM   8930  N N   . THR E 1 131 ? -33.948 48.459  -7.770   1.00 54.10  ? 132 THR I N   1 
ATOM   8931  C CA  . THR E 1 131 ? -33.869 47.942  -9.132   1.00 57.18  ? 132 THR I CA  1 
ATOM   8932  C C   . THR E 1 131 ? -32.946 48.761  -10.026  1.00 50.86  ? 132 THR I C   1 
ATOM   8933  O O   . THR E 1 131 ? -32.915 48.529  -11.240  1.00 60.98  ? 132 THR I O   1 
ATOM   8934  C CB  . THR E 1 131 ? -35.262 47.880  -9.767   1.00 66.38  ? 132 THR I CB  1 
ATOM   8935  O OG1 . THR E 1 131 ? -35.769 49.209  -9.941   1.00 64.48  ? 132 THR I OG1 1 
ATOM   8936  C CG2 . THR E 1 131 ? -36.214 47.092  -8.888   1.00 61.47  ? 132 THR I CG2 1 
ATOM   8937  N N   . SER E 1 132 ? -32.195 49.708  -9.466   1.00 61.40  ? 133 SER I N   1 
ATOM   8938  C CA  . SER E 1 132 ? -31.371 50.604  -10.262  1.00 61.12  ? 133 SER I CA  1 
ATOM   8939  C C   . SER E 1 132 ? -29.888 50.543  -9.930   1.00 57.58  ? 133 SER I C   1 
ATOM   8940  O O   . SER E 1 132 ? -29.090 51.162  -10.645  1.00 79.68  ? 133 SER I O   1 
ATOM   8941  C CB  . SER E 1 132 ? -31.857 52.053  -10.103  1.00 62.01  ? 133 SER I CB  1 
ATOM   8942  O OG  . SER E 1 132 ? -33.251 52.146  -10.337  1.00 71.87  ? 133 SER I OG  1 
ATOM   8943  N N   . LEU E 1 133 A -29.492 49.836  -8.875   1.00 57.99  ? 133 LEU I N   1 
ATOM   8944  C CA  . LEU E 1 133 A -28.085 49.699  -8.526   1.00 53.84  ? 133 LEU I CA  1 
ATOM   8945  C C   . LEU E 1 133 A -27.447 48.445  -9.107   1.00 69.91  ? 133 LEU I C   1 
ATOM   8946  O O   . LEU E 1 133 A -26.245 48.236  -8.916   1.00 64.06  ? 133 LEU I O   1 
ATOM   8947  C CB  . LEU E 1 133 A -27.913 49.700  -7.004   1.00 57.56  ? 133 LEU I CB  1 
ATOM   8948  C CG  . LEU E 1 133 A -28.240 51.009  -6.284   1.00 74.56  ? 133 LEU I CG  1 
ATOM   8949  C CD1 . LEU E 1 133 A -27.982 50.870  -4.793   1.00 61.18  ? 133 LEU I CD1 1 
ATOM   8950  C CD2 . LEU E 1 133 A -27.434 52.161  -6.868   1.00 58.12  ? 133 LEU I CD2 1 
ATOM   8951  N N   . GLY E 1 134 ? -28.209 47.616  -9.814   1.00 62.12  ? 134 GLY I N   1 
ATOM   8952  C CA  . GLY E 1 134 ? -27.671 46.385  -10.355  1.00 56.40  ? 134 GLY I CA  1 
ATOM   8953  C C   . GLY E 1 134 ? -26.829 46.604  -11.593  1.00 48.77  ? 134 GLY I C   1 
ATOM   8954  O O   . GLY E 1 134 ? -27.232 46.230  -12.697  1.00 60.58  ? 134 GLY I O   1 
ATOM   8955  N N   . VAL E 1 135 ? -25.656 47.212  -11.423  1.00 53.54  ? 135 VAL I N   1 
ATOM   8956  C CA  . VAL E 1 135 ? -24.777 47.548  -12.534  1.00 55.26  ? 135 VAL I CA  1 
ATOM   8957  C C   . VAL E 1 135 ? -23.364 47.095  -12.195  1.00 54.86  ? 135 VAL I C   1 
ATOM   8958  O O   . VAL E 1 135 ? -23.024 46.848  -11.035  1.00 55.64  ? 135 VAL I O   1 
ATOM   8959  C CB  . VAL E 1 135 ? -24.792 49.057  -12.861  1.00 66.28  ? 135 VAL I CB  1 
ATOM   8960  C CG1 . VAL E 1 135 ? -26.181 49.493  -13.307  1.00 42.51  ? 135 VAL I CG1 1 
ATOM   8961  C CG2 . VAL E 1 135 ? -24.335 49.867  -11.657  1.00 47.97  ? 135 VAL I CG2 1 
ATOM   8962  N N   . SER E 1 136 ? -22.537 46.990  -13.232  1.00 50.18  ? 136 SER I N   1 
ATOM   8963  C CA  . SER E 1 136 ? -21.169 46.521  -13.068  1.00 59.64  ? 136 SER I CA  1 
ATOM   8964  C C   . SER E 1 136 ? -20.288 47.122  -14.152  1.00 57.96  ? 136 SER I C   1 
ATOM   8965  O O   . SER E 1 136 ? -20.723 47.287  -15.294  1.00 53.24  ? 136 SER I O   1 
ATOM   8966  C CB  . SER E 1 136 ? -21.095 44.991  -13.127  1.00 62.49  ? 136 SER I CB  1 
ATOM   8967  O OG  . SER E 1 136 ? -19.749 44.549  -13.113  1.00 54.50  ? 136 SER I OG  1 
ATOM   8968  N N   . ALA E 1 137 ? -19.043 47.437  -13.783  1.00 58.30  ? 137 ALA I N   1 
ATOM   8969  C CA  . ALA E 1 137 ? -18.064 47.900  -14.760  1.00 61.16  ? 137 ALA I CA  1 
ATOM   8970  C C   . ALA E 1 137 ? -17.692 46.814  -15.759  1.00 56.01  ? 137 ALA I C   1 
ATOM   8971  O O   . ALA E 1 137 ? -17.137 47.125  -16.818  1.00 69.86  ? 137 ALA I O   1 
ATOM   8972  C CB  . ALA E 1 137 ? -16.808 48.406  -14.051  1.00 54.71  ? 137 ALA I CB  1 
ATOM   8973  N N   . ALA E 1 138 ? -17.977 45.549  -15.443  1.00 59.27  ? 138 ALA I N   1 
ATOM   8974  C CA  . ALA E 1 138 ? -17.777 44.462  -16.393  1.00 64.95  ? 138 ALA I CA  1 
ATOM   8975  C C   . ALA E 1 138 ? -18.778 44.494  -17.540  1.00 64.69  ? 138 ALA I C   1 
ATOM   8976  O O   . ALA E 1 138 ? -18.550 43.824  -18.554  1.00 65.42  ? 138 ALA I O   1 
ATOM   8977  C CB  . ALA E 1 138 ? -17.855 43.114  -15.673  1.00 53.02  ? 138 ALA I CB  1 
ATOM   8978  N N   . CYS E 1 139 ? -19.862 45.264  -17.415  1.00 60.34  ? 139 CYS I N   1 
ATOM   8979  C CA  . CYS E 1 139 ? -20.872 45.418  -18.461  1.00 64.82  ? 139 CYS I CA  1 
ATOM   8980  C C   . CYS E 1 139 ? -21.018 46.903  -18.776  1.00 76.89  ? 139 CYS I C   1 
ATOM   8981  O O   . CYS E 1 139 ? -22.024 47.528  -18.414  1.00 75.64  ? 139 CYS I O   1 
ATOM   8982  C CB  . CYS E 1 139 ? -22.220 44.832  -18.039  1.00 60.98  ? 139 CYS I CB  1 
ATOM   8983  S SG  . CYS E 1 139 ? -22.233 43.063  -17.660  1.00 78.40  ? 139 CYS I SG  1 
ATOM   8984  N N   . PRO E 1 140 ? -20.034 47.501  -19.448  1.00 76.30  ? 140 PRO I N   1 
ATOM   8985  C CA  . PRO E 1 140 ? -20.089 48.945  -19.695  1.00 74.53  ? 140 PRO I CA  1 
ATOM   8986  C C   . PRO E 1 140 ? -20.979 49.294  -20.879  1.00 72.54  ? 140 PRO I C   1 
ATOM   8987  O O   . PRO E 1 140 ? -20.955 48.632  -21.920  1.00 80.65  ? 140 PRO I O   1 
ATOM   8988  C CB  . PRO E 1 140 ? -18.626 49.304  -19.980  1.00 71.05  ? 140 PRO I CB  1 
ATOM   8989  C CG  . PRO E 1 140 ? -18.074 48.071  -20.607  1.00 75.28  ? 140 PRO I CG  1 
ATOM   8990  C CD  . PRO E 1 140 ? -18.786 46.903  -19.958  1.00 78.21  ? 140 PRO I CD  1 
ATOM   8991  N N   . TYR E 1 141 ? -21.774 50.347  -20.704  1.00 86.64  ? 141 TYR I N   1 
ATOM   8992  C CA  . TYR E 1 141 ? -22.538 50.946  -21.792  1.00 92.21  ? 141 TYR I CA  1 
ATOM   8993  C C   . TYR E 1 141 ? -22.233 52.435  -21.827  1.00 92.90  ? 141 TYR I C   1 
ATOM   8994  O O   . TYR E 1 141 ? -22.411 53.129  -20.820  1.00 77.77  ? 141 TYR I O   1 
ATOM   8995  C CB  . TYR E 1 141 ? -24.041 50.707  -21.628  1.00 81.41  ? 141 TYR I CB  1 
ATOM   8996  C CG  . TYR E 1 141 ? -24.855 51.240  -22.785  1.00 94.31  ? 141 TYR I CG  1 
ATOM   8997  C CD1 . TYR E 1 141 ? -24.602 50.820  -24.086  1.00 87.59  ? 141 TYR I CD1 1 
ATOM   8998  C CD2 . TYR E 1 141 ? -25.876 52.161  -22.580  1.00 99.67  ? 141 TYR I CD2 1 
ATOM   8999  C CE1 . TYR E 1 141 ? -25.338 51.304  -25.150  1.00 86.76  ? 141 TYR I CE1 1 
ATOM   9000  C CE2 . TYR E 1 141 ? -26.619 52.650  -23.639  1.00 97.89  ? 141 TYR I CE2 1 
ATOM   9001  C CZ  . TYR E 1 141 ? -26.345 52.218  -24.922  1.00 97.70  ? 141 TYR I CZ  1 
ATOM   9002  O OH  . TYR E 1 141 ? -27.082 52.698  -25.980  1.00 98.82  ? 141 TYR I OH  1 
ATOM   9003  N N   . GLN E 1 142 ? -21.782 52.920  -22.987  1.00 101.25 ? 142 GLN I N   1 
ATOM   9004  C CA  . GLN E 1 142 ? -21.336 54.304  -23.145  1.00 95.82  ? 142 GLN I CA  1 
ATOM   9005  C C   . GLN E 1 142 ? -20.278 54.654  -22.098  1.00 91.58  ? 142 GLN I C   1 
ATOM   9006  O O   . GLN E 1 142 ? -20.277 55.747  -21.530  1.00 84.37  ? 142 GLN I O   1 
ATOM   9007  C CB  . GLN E 1 142 ? -22.518 55.275  -23.085  1.00 88.20  ? 142 GLN I CB  1 
ATOM   9008  C CG  . GLN E 1 142 ? -23.378 55.265  -24.336  1.00 96.92  ? 142 GLN I CG  1 
ATOM   9009  C CD  . GLN E 1 142 ? -24.788 55.767  -24.090  1.00 107.12 ? 142 GLN I CD  1 
ATOM   9010  O OE1 . GLN E 1 142 ? -25.561 55.959  -25.029  1.00 103.59 ? 142 GLN I OE1 1 
ATOM   9011  N NE2 . GLN E 1 142 ? -25.133 55.974  -22.824  1.00 100.47 ? 142 GLN I NE2 1 
ATOM   9012  N N   . GLY E 1 143 ? -19.375 53.704  -21.832  1.00 94.63  ? 143 GLY I N   1 
ATOM   9013  C CA  . GLY E 1 143 ? -18.368 53.852  -20.811  1.00 88.84  ? 143 GLY I CA  1 
ATOM   9014  C C   . GLY E 1 143 ? -18.858 53.724  -19.390  1.00 84.16  ? 143 GLY I C   1 
ATOM   9015  O O   . GLY E 1 143 ? -18.052 53.442  -18.501  1.00 81.03  ? 143 GLY I O   1 
ATOM   9016  N N   . ALA E 1 144 ? -20.170 53.907  -19.141  1.00 77.83  ? 144 ALA I N   1 
ATOM   9017  C CA  . ALA E 1 144 ? -20.751 53.839  -17.811  1.00 81.84  ? 144 ALA I CA  1 
ATOM   9018  C C   . ALA E 1 144 ? -21.064 52.396  -17.427  1.00 74.14  ? 144 ALA I C   1 
ATOM   9019  O O   . ALA E 1 144 ? -21.437 51.584  -18.281  1.00 77.47  ? 144 ALA I O   1 
ATOM   9020  C CB  . ALA E 1 144 ? -22.030 54.669  -17.748  1.00 74.89  ? 144 ALA I CB  1 
ATOM   9021  N N   . PRO E 1 145 ? -20.916 52.063  -16.146  1.00 67.52  ? 145 PRO I N   1 
ATOM   9022  C CA  . PRO E 1 145 ? -21.295 50.719  -15.691  1.00 61.27  ? 145 PRO I CA  1 
ATOM   9023  C C   . PRO E 1 145 ? -22.771 50.452  -15.944  1.00 70.41  ? 145 PRO I C   1 
ATOM   9024  O O   . PRO E 1 145 ? -23.624 51.320  -15.744  1.00 73.92  ? 145 PRO I O   1 
ATOM   9025  C CB  . PRO E 1 145 ? -20.973 50.744  -14.192  1.00 59.76  ? 145 PRO I CB  1 
ATOM   9026  C CG  . PRO E 1 145 ? -19.957 51.845  -14.042  1.00 69.64  ? 145 PRO I CG  1 
ATOM   9027  C CD  . PRO E 1 145 ? -20.331 52.875  -15.064  1.00 62.93  ? 145 PRO I CD  1 
ATOM   9028  N N   . SER E 1 146 ? -23.066 49.237  -16.388  1.00 63.80  ? 146 SER I N   1 
ATOM   9029  C CA  . SER E 1 146 ? -24.421 48.855  -16.765  1.00 68.18  ? 146 SER I CA  1 
ATOM   9030  C C   . SER E 1 146 ? -24.581 47.366  -16.476  1.00 65.90  ? 146 SER I C   1 
ATOM   9031  O O   . SER E 1 146 ? -23.816 46.787  -15.698  1.00 62.80  ? 146 SER I O   1 
ATOM   9032  C CB  . SER E 1 146 ? -24.695 49.227  -18.234  1.00 64.44  ? 146 SER I CB  1 
ATOM   9033  O OG  . SER E 1 146 ? -26.045 48.978  -18.581  1.00 68.31  ? 146 SER I OG  1 
ATOM   9034  N N   . PHE E 1 147 ? -25.589 46.747  -17.084  1.00 55.36  ? 147 PHE I N   1 
ATOM   9035  C CA  . PHE E 1 147 ? -25.892 45.344  -16.846  1.00 57.56  ? 147 PHE I CA  1 
ATOM   9036  C C   . PHE E 1 147 ? -26.672 44.816  -18.042  1.00 57.10  ? 147 PHE I C   1 
ATOM   9037  O O   . PHE E 1 147 ? -27.006 45.563  -18.967  1.00 56.95  ? 147 PHE I O   1 
ATOM   9038  C CB  . PHE E 1 147 ? -26.667 45.174  -15.536  1.00 57.98  ? 147 PHE I CB  1 
ATOM   9039  C CG  . PHE E 1 147 ? -26.765 43.753  -15.061  1.00 53.24  ? 147 PHE I CG  1 
ATOM   9040  C CD1 . PHE E 1 147 ? -25.633 43.060  -14.667  1.00 56.57  ? 147 PHE I CD1 1 
ATOM   9041  C CD2 . PHE E 1 147 ? -27.991 43.114  -14.999  1.00 47.09  ? 147 PHE I CD2 1 
ATOM   9042  C CE1 . PHE E 1 147 ? -25.722 41.754  -14.228  1.00 57.29  ? 147 PHE I CE1 1 
ATOM   9043  C CE2 . PHE E 1 147 ? -28.087 41.808  -14.560  1.00 54.27  ? 147 PHE I CE2 1 
ATOM   9044  C CZ  . PHE E 1 147 ? -26.951 41.128  -14.174  1.00 53.48  ? 147 PHE I CZ  1 
ATOM   9045  N N   . PHE E 1 148 ? -26.952 43.514  -18.020  1.00 56.43  ? 148 PHE I N   1 
ATOM   9046  C CA  . PHE E 1 148 ? -27.792 42.903  -19.042  1.00 60.87  ? 148 PHE I CA  1 
ATOM   9047  C C   . PHE E 1 148 ? -29.137 43.618  -19.114  1.00 56.12  ? 148 PHE I C   1 
ATOM   9048  O O   . PHE E 1 148 ? -29.718 43.991  -18.091  1.00 57.81  ? 148 PHE I O   1 
ATOM   9049  C CB  . PHE E 1 148 ? -28.012 41.418  -18.739  1.00 53.74  ? 148 PHE I CB  1 
ATOM   9050  C CG  . PHE E 1 148 ? -26.757 40.587  -18.769  1.00 52.43  ? 148 PHE I CG  1 
ATOM   9051  C CD1 . PHE E 1 148 ? -26.130 40.295  -19.970  1.00 58.10  ? 148 PHE I CD1 1 
ATOM   9052  C CD2 . PHE E 1 148 ? -26.225 40.069  -17.600  1.00 53.84  ? 148 PHE I CD2 1 
ATOM   9053  C CE1 . PHE E 1 148 ? -24.983 39.520  -20.001  1.00 43.10  ? 148 PHE I CE1 1 
ATOM   9054  C CE2 . PHE E 1 148 ? -25.079 39.291  -17.625  1.00 51.15  ? 148 PHE I CE2 1 
ATOM   9055  C CZ  . PHE E 1 148 ? -24.458 39.018  -18.827  1.00 50.77  ? 148 PHE I CZ  1 
ATOM   9056  N N   . ARG E 1 149 ? -29.627 43.820  -20.340  1.00 64.65  ? 149 ARG I N   1 
ATOM   9057  C CA  . ARG E 1 149 ? -30.862 44.578  -20.529  1.00 62.87  ? 149 ARG I CA  1 
ATOM   9058  C C   . ARG E 1 149 ? -32.081 43.807  -20.037  1.00 62.82  ? 149 ARG I C   1 
ATOM   9059  O O   . ARG E 1 149 ? -32.964 44.379  -19.388  1.00 68.99  ? 149 ARG I O   1 
ATOM   9060  C CB  . ARG E 1 149 ? -31.043 44.936  -22.005  1.00 63.60  ? 149 ARG I CB  1 
ATOM   9061  C CG  . ARG E 1 149 ? -29.869 45.646  -22.646  1.00 82.31  ? 149 ARG I CG  1 
ATOM   9062  C CD  . ARG E 1 149 ? -29.771 47.094  -22.209  1.00 80.91  ? 149 ARG I CD  1 
ATOM   9063  N NE  . ARG E 1 149 ? -28.965 47.865  -23.148  1.00 91.66  ? 149 ARG I NE  1 
ATOM   9064  C CZ  . ARG E 1 149 ? -28.525 49.095  -22.929  1.00 97.25  ? 149 ARG I CZ  1 
ATOM   9065  N NH1 . ARG E 1 149 ? -28.777 49.729  -21.795  1.00 104.53 ? 149 ARG I NH1 1 
ATOM   9066  N NH2 . ARG E 1 149 ? -27.809 49.703  -23.869  1.00 97.81  ? 149 ARG I NH2 1 
ATOM   9067  N N   . ASN E 1 150 ? -32.149 42.512  -20.336  1.00 54.37  ? 150 ASN I N   1 
ATOM   9068  C CA  . ASN E 1 150 ? -33.381 41.746  -20.201  1.00 54.86  ? 150 ASN I CA  1 
ATOM   9069  C C   . ASN E 1 150 ? -33.576 41.136  -18.820  1.00 56.19  ? 150 ASN I C   1 
ATOM   9070  O O   . ASN E 1 150 ? -34.595 40.472  -18.595  1.00 59.14  ? 150 ASN I O   1 
ATOM   9071  C CB  . ASN E 1 150 ? -33.424 40.647  -21.266  1.00 50.96  ? 150 ASN I CB  1 
ATOM   9072  C CG  . ASN E 1 150 ? -33.325 41.205  -22.673  1.00 64.35  ? 150 ASN I CG  1 
ATOM   9073  O OD1 . ASN E 1 150 ? -33.910 42.245  -22.981  1.00 62.18  ? 150 ASN I OD1 1 
ATOM   9074  N ND2 . ASN E 1 150 ? -32.572 40.526  -23.530  1.00 55.79  ? 150 ASN I ND2 1 
ATOM   9075  N N   . VAL E 1 151 ? -32.638 41.335  -17.894  1.00 51.30  ? 151 VAL I N   1 
ATOM   9076  C CA  . VAL E 1 151 ? -32.788 40.882  -16.518  1.00 52.43  ? 151 VAL I CA  1 
ATOM   9077  C C   . VAL E 1 151 ? -32.402 42.026  -15.591  1.00 50.20  ? 151 VAL I C   1 
ATOM   9078  O O   . VAL E 1 151 ? -31.702 42.963  -15.978  1.00 54.47  ? 151 VAL I O   1 
ATOM   9079  C CB  . VAL E 1 151 ? -31.946 39.622  -16.213  1.00 56.73  ? 151 VAL I CB  1 
ATOM   9080  C CG1 . VAL E 1 151 ? -32.498 38.423  -16.961  1.00 44.03  ? 151 VAL I CG1 1 
ATOM   9081  C CG2 . VAL E 1 151 ? -30.488 39.850  -16.580  1.00 48.92  ? 151 VAL I CG2 1 
ATOM   9082  N N   . VAL E 1 152 ? -32.878 41.944  -14.351  1.00 48.74  ? 152 VAL I N   1 
ATOM   9083  C CA  . VAL E 1 152 ? -32.682 42.998  -13.364  1.00 52.31  ? 152 VAL I CA  1 
ATOM   9084  C C   . VAL E 1 152 ? -31.982 42.408  -12.147  1.00 49.62  ? 152 VAL I C   1 
ATOM   9085  O O   . VAL E 1 152 ? -32.370 41.343  -11.651  1.00 58.51  ? 152 VAL I O   1 
ATOM   9086  C CB  . VAL E 1 152 ? -34.013 43.671  -12.974  1.00 61.18  ? 152 VAL I CB  1 
ATOM   9087  C CG1 . VAL E 1 152 ? -35.026 42.645  -12.492  1.00 61.31  ? 152 VAL I CG1 1 
ATOM   9088  C CG2 . VAL E 1 152 ? -33.781 44.741  -11.919  1.00 52.75  ? 152 VAL I CG2 1 
ATOM   9089  N N   . TRP E 1 153 ? -30.946 43.097  -11.681  1.00 50.96  ? 153 TRP I N   1 
ATOM   9090  C CA  . TRP E 1 153 ? -30.123 42.660  -10.555  1.00 48.72  ? 153 TRP I CA  1 
ATOM   9091  C C   . TRP E 1 153 ? -30.638 43.372  -9.306   1.00 52.92  ? 153 TRP I C   1 
ATOM   9092  O O   . TRP E 1 153 ? -30.231 44.491  -8.992   1.00 53.84  ? 153 TRP I O   1 
ATOM   9093  C CB  . TRP E 1 153 ? -28.656 42.964  -10.841  1.00 46.89  ? 153 TRP I CB  1 
ATOM   9094  C CG  . TRP E 1 153 ? -27.678 42.521  -9.800   1.00 46.18  ? 153 TRP I CG  1 
ATOM   9095  C CD1 . TRP E 1 153 ? -27.946 41.876  -8.628   1.00 39.47  ? 153 TRP I CD1 1 
ATOM   9096  C CD2 . TRP E 1 153 ? -26.257 42.693  -9.848   1.00 49.86  ? 153 TRP I CD2 1 
ATOM   9097  N NE1 . TRP E 1 153 ? -26.778 41.637  -7.941   1.00 46.20  ? 153 TRP I NE1 1 
ATOM   9098  C CE2 . TRP E 1 153 ? -25.727 42.130  -8.669   1.00 40.61  ? 153 TRP I CE2 1 
ATOM   9099  C CE3 . TRP E 1 153 ? -25.382 43.271  -10.773  1.00 40.07  ? 153 TRP I CE3 1 
ATOM   9100  C CZ2 . TRP E 1 153 ? -24.361 42.129  -8.391   1.00 52.07  ? 153 TRP I CZ2 1 
ATOM   9101  C CZ3 . TRP E 1 153 ? -24.025 43.268  -10.497  1.00 44.19  ? 153 TRP I CZ3 1 
ATOM   9102  C CH2 . TRP E 1 153 ? -23.528 42.700  -9.315   1.00 49.80  ? 153 TRP I CH2 1 
ATOM   9103  N N   . LEU E 1 154 ? -31.538 42.704  -8.587   1.00 49.87  ? 154 LEU I N   1 
ATOM   9104  C CA  . LEU E 1 154 ? -32.188 43.307  -7.431   1.00 51.11  ? 154 LEU I CA  1 
ATOM   9105  C C   . LEU E 1 154 ? -31.225 43.427  -6.257   1.00 48.02  ? 154 LEU I C   1 
ATOM   9106  O O   . LEU E 1 154 ? -30.445 42.514  -5.972   1.00 61.27  ? 154 LEU I O   1 
ATOM   9107  C CB  . LEU E 1 154 ? -33.406 42.480  -7.024   1.00 43.97  ? 154 LEU I CB  1 
ATOM   9108  C CG  . LEU E 1 154 ? -34.397 42.159  -8.145   1.00 54.78  ? 154 LEU I CG  1 
ATOM   9109  C CD1 . LEU E 1 154 ? -35.424 41.147  -7.671   1.00 55.68  ? 154 LEU I CD1 1 
ATOM   9110  C CD2 . LEU E 1 154 ? -35.079 43.424  -8.642   1.00 53.15  ? 154 LEU I CD2 1 
ATOM   9111  N N   . ILE E 1 155 ? -31.299 44.561  -5.564   1.00 55.03  ? 155 ILE I N   1 
ATOM   9112  C CA  . ILE E 1 155 ? -30.427 44.879  -4.442   1.00 61.91  ? 155 ILE I CA  1 
ATOM   9113  C C   . ILE E 1 155 ? -31.306 45.258  -3.257   1.00 57.07  ? 155 ILE I C   1 
ATOM   9114  O O   . ILE E 1 155 ? -32.454 45.682  -3.427   1.00 64.74  ? 155 ILE I O   1 
ATOM   9115  C CB  . ILE E 1 155 ? -29.435 46.013  -4.813   1.00 48.65  ? 155 ILE I CB  1 
ATOM   9116  C CG1 . ILE E 1 155 ? -28.504 45.546  -5.932   1.00 60.51  ? 155 ILE I CG1 1 
ATOM   9117  C CG2 . ILE E 1 155 ? -28.593 46.458  -3.628   1.00 52.35  ? 155 ILE I CG2 1 
ATOM   9118  C CD1 . ILE E 1 155 ? -27.623 44.376  -5.535   1.00 51.67  ? 155 ILE I CD1 1 
ATOM   9119  N N   . LYS E 1 156 ? -30.774 45.075  -2.049   1.00 63.11  ? 156 LYS I N   1 
ATOM   9120  C CA  . LYS E 1 156 ? -31.507 45.436  -0.843   1.00 63.96  ? 156 LYS I CA  1 
ATOM   9121  C C   . LYS E 1 156 ? -31.880 46.915  -0.862   1.00 61.24  ? 156 LYS I C   1 
ATOM   9122  O O   . LYS E 1 156 ? -31.157 47.758  -1.401   1.00 59.73  ? 156 LYS I O   1 
ATOM   9123  C CB  . LYS E 1 156 ? -30.670 45.131  0.401    1.00 52.52  ? 156 LYS I CB  1 
ATOM   9124  C CG  . LYS E 1 156 ? -29.473 46.055  0.582    1.00 59.00  ? 156 LYS I CG  1 
ATOM   9125  C CD  . LYS E 1 156 ? -28.757 45.821  1.904    1.00 48.87  ? 156 LYS I CD  1 
ATOM   9126  C CE  . LYS E 1 156 ? -27.637 46.834  2.096    1.00 59.61  ? 156 LYS I CE  1 
ATOM   9127  N NZ  . LYS E 1 156 ? -26.837 46.569  3.323    1.00 62.81  ? 156 LYS I NZ  1 
ATOM   9128  N N   . LYS E 1 157 ? -33.039 47.224  -0.287   1.00 62.89  ? 157 LYS I N   1 
ATOM   9129  C CA  . LYS E 1 157 ? -33.495 48.597  -0.126   1.00 69.76  ? 157 LYS I CA  1 
ATOM   9130  C C   . LYS E 1 157 ? -33.764 48.868  1.347    1.00 62.08  ? 157 LYS I C   1 
ATOM   9131  O O   . LYS E 1 157 ? -34.372 48.043  2.037    1.00 70.30  ? 157 LYS I O   1 
ATOM   9132  C CB  . LYS E 1 157 ? -34.758 48.880  -0.946   1.00 68.46  ? 157 LYS I CB  1 
ATOM   9133  C CG  . LYS E 1 157 ? -35.016 50.367  -1.139   1.00 72.84  ? 157 LYS I CG  1 
ATOM   9134  C CD  . LYS E 1 157 ? -36.499 50.693  -1.224   1.00 83.64  ? 157 LYS I CD  1 
ATOM   9135  C CE  . LYS E 1 157 ? -37.118 50.196  -2.518   1.00 71.03  ? 157 LYS I CE  1 
ATOM   9136  N NZ  . LYS E 1 157 ? -38.494 50.741  -2.700   1.00 73.61  ? 157 LYS I NZ  1 
ATOM   9137  N N   . ASN E 1 158 ? -33.310 50.033  1.817    1.00 71.50  ? 158 ASN I N   1 
ATOM   9138  C CA  . ASN E 1 158 ? -33.421 50.416  3.226    1.00 62.95  ? 158 ASN I CA  1 
ATOM   9139  C C   . ASN E 1 158 ? -32.755 49.380  4.128    1.00 61.13  ? 158 ASN I C   1 
ATOM   9140  O O   . ASN E 1 158 ? -33.249 49.067  5.213    1.00 74.87  ? 158 ASN I O   1 
ATOM   9141  C CB  . ASN E 1 158 ? -34.881 50.635  3.629    1.00 72.81  ? 158 ASN I CB  1 
ATOM   9142  C CG  . ASN E 1 158 ? -35.607 51.583  2.694    1.00 84.13  ? 158 ASN I CG  1 
ATOM   9143  O OD1 . ASN E 1 158 ? -35.054 52.597  2.264    1.00 74.83  ? 158 ASN I OD1 1 
ATOM   9144  N ND2 . ASN E 1 158 ? -36.852 51.254  2.369    1.00 74.43  ? 158 ASN I ND2 1 
ATOM   9145  N N   . ASP E 1 159 ? -31.621 48.847  3.666    1.00 77.81  ? 159 ASP I N   1 
ATOM   9146  C CA  . ASP E 1 159 ? -30.856 47.837  4.399    1.00 68.54  ? 159 ASP I CA  1 
ATOM   9147  C C   . ASP E 1 159 ? -31.720 46.621  4.733    1.00 60.69  ? 159 ASP I C   1 
ATOM   9148  O O   . ASP E 1 159 ? -31.645 46.062  5.829    1.00 69.15  ? 159 ASP I O   1 
ATOM   9149  C CB  . ASP E 1 159 ? -30.229 48.435  5.661    1.00 69.61  ? 159 ASP I CB  1 
ATOM   9150  C CG  . ASP E 1 159 ? -28.913 47.777  6.031    1.00 90.27  ? 159 ASP I CG  1 
ATOM   9151  O OD1 . ASP E 1 159 ? -28.923 46.586  6.402    1.00 95.22  ? 159 ASP I OD1 1 
ATOM   9152  O OD2 . ASP E 1 159 ? -27.864 48.449  5.939    1.00 101.51 ? 159 ASP I OD2 1 
ATOM   9153  N N   . ALA E 1 160 ? -32.552 46.209  3.777    1.00 65.24  ? 160 ALA I N   1 
ATOM   9154  C CA  . ALA E 1 160 ? -33.410 45.047  3.955    1.00 61.12  ? 160 ALA I CA  1 
ATOM   9155  C C   . ALA E 1 160 ? -33.737 44.445  2.596    1.00 63.12  ? 160 ALA I C   1 
ATOM   9156  O O   . ALA E 1 160 ? -33.856 45.157  1.596    1.00 54.41  ? 160 ALA I O   1 
ATOM   9157  C CB  . ALA E 1 160 ? -34.701 45.406  4.699    1.00 65.05  ? 160 ALA I CB  1 
ATOM   9158  N N   . TYR E 1 161 ? -33.882 43.120  2.575    1.00 55.05  ? 161 TYR I N   1 
ATOM   9159  C CA  . TYR E 1 161 ? -34.218 42.365  1.368    1.00 58.52  ? 161 TYR I CA  1 
ATOM   9160  C C   . TYR E 1 161 ? -35.380 41.445  1.711    1.00 57.02  ? 161 TYR I C   1 
ATOM   9161  O O   . TYR E 1 161 ? -35.179 40.269  2.047    1.00 59.26  ? 161 TYR I O   1 
ATOM   9162  C CB  . TYR E 1 161 ? -33.012 41.577  0.852    1.00 57.02  ? 161 TYR I CB  1 
ATOM   9163  C CG  . TYR E 1 161 ? -33.134 41.068  -0.573   1.00 54.03  ? 161 TYR I CG  1 
ATOM   9164  C CD1 . TYR E 1 161 ? -34.012 40.041  -0.897   1.00 42.33  ? 161 TYR I CD1 1 
ATOM   9165  C CD2 . TYR E 1 161 ? -32.349 41.600  -1.589   1.00 47.22  ? 161 TYR I CD2 1 
ATOM   9166  C CE1 . TYR E 1 161 ? -34.119 39.571  -2.194   1.00 56.13  ? 161 TYR I CE1 1 
ATOM   9167  C CE2 . TYR E 1 161 ? -32.447 41.134  -2.888   1.00 53.43  ? 161 TYR I CE2 1 
ATOM   9168  C CZ  . TYR E 1 161 ? -33.331 40.119  -3.184   1.00 51.07  ? 161 TYR I CZ  1 
ATOM   9169  O OH  . TYR E 1 161 ? -33.432 39.653  -4.474   1.00 53.26  ? 161 TYR I OH  1 
ATOM   9170  N N   . PRO E 1 162 ? -36.611 41.950  1.655    1.00 61.04  ? 162 PRO I N   1 
ATOM   9171  C CA  . PRO E 1 162 ? -37.767 41.110  1.989    1.00 60.53  ? 162 PRO I CA  1 
ATOM   9172  C C   . PRO E 1 162 ? -37.894 39.940  1.027    1.00 53.74  ? 162 PRO I C   1 
ATOM   9173  O O   . PRO E 1 162 ? -37.533 40.031  -0.149   1.00 54.61  ? 162 PRO I O   1 
ATOM   9174  C CB  . PRO E 1 162 ? -38.958 42.070  1.861    1.00 63.04  ? 162 PRO I CB  1 
ATOM   9175  C CG  . PRO E 1 162 ? -38.362 43.444  1.892    1.00 57.10  ? 162 PRO I CG  1 
ATOM   9176  C CD  . PRO E 1 162 ? -37.008 43.317  1.281    1.00 55.66  ? 162 PRO I CD  1 
ATOM   9177  N N   . THR E 1 163 ? -38.411 38.827  1.543    1.00 65.55  ? 163 THR I N   1 
ATOM   9178  C CA  . THR E 1 163 ? -38.563 37.632  0.725    1.00 52.14  ? 163 THR I CA  1 
ATOM   9179  C C   . THR E 1 163 ? -39.521 37.896  -0.429   1.00 51.13  ? 163 THR I C   1 
ATOM   9180  O O   . THR E 1 163 ? -40.615 38.434  -0.237   1.00 72.12  ? 163 THR I O   1 
ATOM   9181  C CB  . THR E 1 163 ? -39.061 36.464  1.576    1.00 50.54  ? 163 THR I CB  1 
ATOM   9182  O OG1 . THR E 1 163 ? -38.162 36.257  2.672    1.00 58.74  ? 163 THR I OG1 1 
ATOM   9183  C CG2 . THR E 1 163 ? -39.135 35.192  0.746    1.00 58.64  ? 163 THR I CG2 1 
ATOM   9184  N N   . ILE E 1 164 ? -39.101 37.512  -1.629   1.00 50.37  ? 164 ILE I N   1 
ATOM   9185  C CA  . ILE E 1 164 ? -39.874 37.735  -2.845   1.00 54.23  ? 164 ILE I CA  1 
ATOM   9186  C C   . ILE E 1 164 ? -40.765 36.524  -3.089   1.00 66.93  ? 164 ILE I C   1 
ATOM   9187  O O   . ILE E 1 164 ? -40.318 35.378  -2.962   1.00 54.88  ? 164 ILE I O   1 
ATOM   9188  C CB  . ILE E 1 164 ? -38.946 37.980  -4.045   1.00 51.61  ? 164 ILE I CB  1 
ATOM   9189  C CG1 . ILE E 1 164 ? -38.084 39.222  -3.809   1.00 54.24  ? 164 ILE I CG1 1 
ATOM   9190  C CG2 . ILE E 1 164 ? -39.746 38.106  -5.325   1.00 58.54  ? 164 ILE I CG2 1 
ATOM   9191  C CD1 . ILE E 1 164 ? -37.062 39.461  -4.896   1.00 52.98  ? 164 ILE I CD1 1 
ATOM   9192  N N   . LYS E 1 165 ? -42.033 36.772  -3.429   1.00 66.12  ? 165 LYS I N   1 
ATOM   9193  C CA  . LYS E 1 165 ? -42.971 35.716  -3.823   1.00 54.07  ? 165 LYS I CA  1 
ATOM   9194  C C   . LYS E 1 165 ? -43.802 36.268  -4.979   1.00 60.22  ? 165 LYS I C   1 
ATOM   9195  O O   . LYS E 1 165 ? -44.811 36.946  -4.766   1.00 76.72  ? 165 LYS I O   1 
ATOM   9196  C CB  . LYS E 1 165 ? -43.843 35.265  -2.657   1.00 59.49  ? 165 LYS I CB  1 
ATOM   9197  C CG  . LYS E 1 165 ? -43.101 34.489  -1.580   1.00 62.96  ? 165 LYS I CG  1 
ATOM   9198  C CD  . LYS E 1 165 ? -44.047 33.982  -0.502   1.00 61.67  ? 165 LYS I CD  1 
ATOM   9199  C CE  . LYS E 1 165 ? -43.295 33.207  0.570    1.00 71.69  ? 165 LYS I CE  1 
ATOM   9200  N NZ  . LYS E 1 165 ? -44.195 32.733  1.658    1.00 79.99  ? 165 LYS I NZ  1 
ATOM   9201  N N   . ILE E 1 166 ? -43.375 35.971  -6.204   1.00 50.56  ? 166 ILE I N   1 
ATOM   9202  C CA  . ILE E 1 166 ? -44.031 36.472  -7.402   1.00 57.41  ? 166 ILE I CA  1 
ATOM   9203  C C   . ILE E 1 166 ? -44.302 35.305  -8.341   1.00 63.57  ? 166 ILE I C   1 
ATOM   9204  O O   . ILE E 1 166 ? -43.581 34.302  -8.342   1.00 64.27  ? 166 ILE I O   1 
ATOM   9205  C CB  . ILE E 1 166 ? -43.187 37.568  -8.098   1.00 62.35  ? 166 ILE I CB  1 
ATOM   9206  C CG1 . ILE E 1 166 ? -43.989 38.248  -9.212   1.00 76.36  ? 166 ILE I CG1 1 
ATOM   9207  C CG2 . ILE E 1 166 ? -41.886 36.989  -8.640   1.00 57.98  ? 166 ILE I CG2 1 
ATOM   9208  C CD1 . ILE E 1 166 ? -43.815 39.751  -9.263   1.00 63.93  ? 166 ILE I CD1 1 
ATOM   9209  N N   . SER E 1 167 ? -45.367 35.434  -9.131   1.00 68.42  ? 167 SER I N   1 
ATOM   9210  C CA  . SER E 1 167 ? -45.739 34.444  -10.129  1.00 69.14  ? 167 SER I CA  1 
ATOM   9211  C C   . SER E 1 167 ? -46.093 35.143  -11.433  1.00 58.11  ? 167 SER I C   1 
ATOM   9212  O O   . SER E 1 167 ? -46.507 36.306  -11.443  1.00 64.26  ? 167 SER I O   1 
ATOM   9213  C CB  . SER E 1 167 ? -46.926 33.583  -9.670   1.00 59.72  ? 167 SER I CB  1 
ATOM   9214  O OG  . SER E 1 167 ? -46.542 32.676  -8.653   1.00 83.09  ? 167 SER I OG  1 
ATOM   9215  N N   . TYR E 1 168 ? -45.918 34.421  -12.537  1.00 55.74  ? 168 TYR I N   1 
ATOM   9216  C CA  . TYR E 1 168 ? -46.329 34.900  -13.850  1.00 58.24  ? 168 TYR I CA  1 
ATOM   9217  C C   . TYR E 1 168 ? -46.993 33.756  -14.599  1.00 63.93  ? 168 TYR I C   1 
ATOM   9218  O O   . TYR E 1 168 ? -46.369 32.714  -14.820  1.00 62.14  ? 168 TYR I O   1 
ATOM   9219  C CB  . TYR E 1 168 ? -45.145 35.447  -14.652  1.00 56.58  ? 168 TYR I CB  1 
ATOM   9220  C CG  . TYR E 1 168 ? -45.513 35.766  -16.080  1.00 65.10  ? 168 TYR I CG  1 
ATOM   9221  C CD1 . TYR E 1 168 ? -46.182 36.941  -16.398  1.00 61.13  ? 168 TYR I CD1 1 
ATOM   9222  C CD2 . TYR E 1 168 ? -45.208 34.886  -17.110  1.00 62.02  ? 168 TYR I CD2 1 
ATOM   9223  C CE1 . TYR E 1 168 ? -46.532 37.232  -17.701  1.00 55.32  ? 168 TYR I CE1 1 
ATOM   9224  C CE2 . TYR E 1 168 ? -45.554 35.169  -18.414  1.00 56.66  ? 168 TYR I CE2 1 
ATOM   9225  C CZ  . TYR E 1 168 ? -46.214 36.344  -18.705  1.00 65.42  ? 168 TYR I CZ  1 
ATOM   9226  O OH  . TYR E 1 168 ? -46.560 36.631  -20.006  1.00 73.34  ? 168 TYR I OH  1 
ATOM   9227  N N   . ASN E 1 169 ? -48.246 33.959  -14.996  1.00 59.31  ? 169 ASN I N   1 
ATOM   9228  C CA  . ASN E 1 169 ? -49.015 32.977  -15.748  1.00 60.39  ? 169 ASN I CA  1 
ATOM   9229  C C   . ASN E 1 169 ? -48.917 33.312  -17.231  1.00 54.62  ? 169 ASN I C   1 
ATOM   9230  O O   . ASN E 1 169 ? -49.157 34.456  -17.631  1.00 63.87  ? 169 ASN I O   1 
ATOM   9231  C CB  . ASN E 1 169 ? -50.474 32.974  -15.275  1.00 60.85  ? 169 ASN I CB  1 
ATOM   9232  C CG  . ASN E 1 169 ? -51.324 31.892  -15.934  1.00 63.99  ? 169 ASN I CG  1 
ATOM   9233  O OD1 . ASN E 1 169 ? -51.282 31.696  -17.149  1.00 59.93  ? 169 ASN I OD1 1 
ATOM   9234  N ND2 . ASN E 1 169 ? -52.112 31.188  -15.121  1.00 77.21  ? 169 ASN I ND2 1 
ATOM   9235  N N   . ASN E 1 170 ? -48.556 32.317  -18.039  1.00 57.36  ? 170 ASN I N   1 
ATOM   9236  C CA  . ASN E 1 170 ? -48.355 32.515  -19.475  1.00 58.88  ? 170 ASN I CA  1 
ATOM   9237  C C   . ASN E 1 170 ? -49.716 32.532  -20.160  1.00 60.87  ? 170 ASN I C   1 
ATOM   9238  O O   . ASN E 1 170 ? -50.273 31.493  -20.518  1.00 60.66  ? 170 ASN I O   1 
ATOM   9239  C CB  . ASN E 1 170 ? -47.457 31.427  -20.051  1.00 61.81  ? 170 ASN I CB  1 
ATOM   9240  C CG  . ASN E 1 170 ? -47.220 31.593  -21.541  1.00 58.90  ? 170 ASN I CG  1 
ATOM   9241  O OD1 . ASN E 1 170 ? -47.373 32.685  -22.089  1.00 56.62  ? 170 ASN I OD1 1 
ATOM   9242  N ND2 . ASN E 1 170 ? -46.842 30.508  -22.204  1.00 60.34  ? 170 ASN I ND2 1 
ATOM   9243  N N   . THR E 1 171 ? -50.254 33.737  -20.353  1.00 62.86  ? 171 THR I N   1 
ATOM   9244  C CA  . THR E 1 171 ? -51.548 33.902  -21.002  1.00 66.19  ? 171 THR I CA  1 
ATOM   9245  C C   . THR E 1 171 ? -51.454 33.921  -22.522  1.00 72.95  ? 171 THR I C   1 
ATOM   9246  O O   . THR E 1 171 ? -52.494 33.909  -23.189  1.00 81.41  ? 171 THR I O   1 
ATOM   9247  C CB  . THR E 1 171 ? -52.220 35.191  -20.518  1.00 64.26  ? 171 THR I CB  1 
ATOM   9248  O OG1 . THR E 1 171 ? -51.366 36.309  -20.796  1.00 79.36  ? 171 THR I OG1 1 
ATOM   9249  C CG2 . THR E 1 171 ? -52.489 35.124  -19.021  1.00 47.01  ? 171 THR I CG2 1 
ATOM   9250  N N   . ASN E 1 172 ? -50.247 33.950  -23.080  1.00 63.25  ? 172 ASN I N   1 
ATOM   9251  C CA  . ASN E 1 172 ? -50.075 33.984  -24.522  1.00 66.24  ? 172 ASN I CA  1 
ATOM   9252  C C   . ASN E 1 172 ? -50.393 32.618  -25.130  1.00 70.95  ? 172 ASN I C   1 
ATOM   9253  O O   . ASN E 1 172 ? -50.486 31.600  -24.439  1.00 70.85  ? 172 ASN I O   1 
ATOM   9254  C CB  . ASN E 1 172 ? -48.650 34.408  -24.879  1.00 64.50  ? 172 ASN I CB  1 
ATOM   9255  C CG  . ASN E 1 172 ? -48.174 35.599  -24.065  1.00 68.25  ? 172 ASN I CG  1 
ATOM   9256  O OD1 . ASN E 1 172 ? -48.291 36.747  -24.494  1.00 75.03  ? 172 ASN I OD1 1 
ATOM   9257  N ND2 . ASN E 1 172 ? -47.633 35.328  -22.884  1.00 64.87  ? 172 ASN I ND2 1 
ATOM   9258  N N   . ARG E 1 173 ? -50.567 32.605  -26.452  1.00 70.01  ? 173 ARG I N   1 
ATOM   9259  C CA  . ARG E 1 173 ? -50.861 31.370  -27.167  1.00 75.48  ? 173 ARG I CA  1 
ATOM   9260  C C   . ARG E 1 173 ? -49.621 30.532  -27.447  1.00 77.10  ? 173 ARG I C   1 
ATOM   9261  O O   . ARG E 1 173 ? -49.758 29.388  -27.895  1.00 76.40  ? 173 ARG I O   1 
ATOM   9262  C CB  . ARG E 1 173 ? -51.558 31.677  -28.496  1.00 92.34  ? 173 ARG I CB  1 
ATOM   9263  C CG  . ARG E 1 173 ? -52.740 32.626  -28.398  1.00 105.79 ? 173 ARG I CG  1 
ATOM   9264  C CD  . ARG E 1 173 ? -53.875 32.033  -27.584  1.00 112.27 ? 173 ARG I CD  1 
ATOM   9265  N NE  . ARG E 1 173 ? -55.087 32.836  -27.691  1.00 128.91 ? 173 ARG I NE  1 
ATOM   9266  C CZ  . ARG E 1 173 ? -55.327 33.929  -26.980  1.00 129.37 ? 173 ARG I CZ  1 
ATOM   9267  N NH1 . ARG E 1 173 ? -54.454 34.385  -26.096  1.00 117.88 ? 173 ARG I NH1 1 
ATOM   9268  N NH2 . ARG E 1 173 ? -56.471 34.584  -27.163  1.00 133.08 ? 173 ARG I NH2 1 
ATOM   9269  N N   . GLU E 1 174 ? -48.426 31.061  -27.198  1.00 77.45  ? 174 GLU I N   1 
ATOM   9270  C CA  . GLU E 1 174 ? -47.186 30.412  -27.592  1.00 81.68  ? 174 GLU I CA  1 
ATOM   9271  C C   . GLU E 1 174 ? -46.308 30.139  -26.377  1.00 72.13  ? 174 GLU I C   1 
ATOM   9272  O O   . GLU E 1 174 ? -46.489 30.725  -25.306  1.00 67.69  ? 174 GLU I O   1 
ATOM   9273  C CB  . GLU E 1 174 ? -46.414 31.268  -28.607  1.00 76.15  ? 174 GLU I CB  1 
ATOM   9274  C CG  . GLU E 1 174 ? -47.183 31.567  -29.886  1.00 87.23  ? 174 GLU I CG  1 
ATOM   9275  C CD  . GLU E 1 174 ? -47.632 33.012  -29.982  1.00 99.62  ? 174 GLU I CD  1 
ATOM   9276  O OE1 . GLU E 1 174 ? -48.153 33.543  -28.978  1.00 90.41  ? 174 GLU I OE1 1 
ATOM   9277  O OE2 . GLU E 1 174 ? -47.458 33.616  -31.062  1.00 90.21  ? 174 GLU I OE2 1 
ATOM   9278  N N   . ASP E 1 175 ? -45.351 29.231  -26.563  1.00 75.85  ? 175 ASP I N   1 
ATOM   9279  C CA  . ASP E 1 175 ? -44.384 28.925  -25.518  1.00 62.94  ? 175 ASP I CA  1 
ATOM   9280  C C   . ASP E 1 175 ? -43.528 30.147  -25.206  1.00 65.51  ? 175 ASP I C   1 
ATOM   9281  O O   . ASP E 1 175 ? -43.280 30.997  -26.065  1.00 64.02  ? 175 ASP I O   1 
ATOM   9282  C CB  . ASP E 1 175 ? -43.485 27.762  -25.943  1.00 58.94  ? 175 ASP I CB  1 
ATOM   9283  C CG  . ASP E 1 175 ? -44.194 26.423  -25.894  1.00 83.66  ? 175 ASP I CG  1 
ATOM   9284  O OD1 . ASP E 1 175 ? -45.144 26.282  -25.098  1.00 89.61  ? 175 ASP I OD1 1 
ATOM   9285  O OD2 . ASP E 1 175 ? -43.796 25.507  -26.645  1.00 88.88  ? 175 ASP I OD2 1 
ATOM   9286  N N   . LEU E 1 176 ? -43.073 30.229  -23.959  1.00 57.89  ? 176 LEU I N   1 
ATOM   9287  C CA  . LEU E 1 176 ? -42.248 31.334  -23.490  1.00 66.94  ? 176 LEU I CA  1 
ATOM   9288  C C   . LEU E 1 176 ? -40.876 30.821  -23.078  1.00 59.80  ? 176 LEU I C   1 
ATOM   9289  O O   . LEU E 1 176 ? -40.771 29.827  -22.352  1.00 57.01  ? 176 LEU I O   1 
ATOM   9290  C CB  . LEU E 1 176 ? -42.908 32.055  -22.311  1.00 61.96  ? 176 LEU I CB  1 
ATOM   9291  C CG  . LEU E 1 176 ? -43.763 33.276  -22.642  1.00 74.00  ? 176 LEU I CG  1 
ATOM   9292  C CD1 . LEU E 1 176 ? -44.350 33.854  -21.371  1.00 59.53  ? 176 LEU I CD1 1 
ATOM   9293  C CD2 . LEU E 1 176 ? -42.937 34.321  -23.371  1.00 72.41  ? 176 LEU I CD2 1 
ATOM   9294  N N   . LEU E 1 177 ? -39.831 31.503  -23.540  1.00 60.08  ? 177 LEU I N   1 
ATOM   9295  C CA  . LEU E 1 177 ? -38.468 31.263  -23.085  1.00 50.98  ? 177 LEU I CA  1 
ATOM   9296  C C   . LEU E 1 177 ? -38.145 32.285  -22.003  1.00 53.47  ? 177 LEU I C   1 
ATOM   9297  O O   . LEU E 1 177 ? -38.149 33.492  -22.265  1.00 54.47  ? 177 LEU I O   1 
ATOM   9298  C CB  . LEU E 1 177 ? -37.476 31.364  -24.243  1.00 53.97  ? 177 LEU I CB  1 
ATOM   9299  C CG  . LEU E 1 177 ? -35.989 31.247  -23.898  1.00 54.45  ? 177 LEU I CG  1 
ATOM   9300  C CD1 . LEU E 1 177 ? -35.682 29.905  -23.249  1.00 49.97  ? 177 LEU I CD1 1 
ATOM   9301  C CD2 . LEU E 1 177 ? -35.133 31.453  -25.142  1.00 55.40  ? 177 LEU I CD2 1 
ATOM   9302  N N   . ILE E 1 178 ? -37.877 31.803  -20.793  1.00 52.72  ? 178 ILE I N   1 
ATOM   9303  C CA  . ILE E 1 178 ? -37.671 32.653  -19.627  1.00 48.86  ? 178 ILE I CA  1 
ATOM   9304  C C   . ILE E 1 178 ? -36.278 32.385  -19.077  1.00 54.14  ? 178 ILE I C   1 
ATOM   9305  O O   . ILE E 1 178 ? -35.889 31.225  -18.902  1.00 52.33  ? 178 ILE I O   1 
ATOM   9306  C CB  . ILE E 1 178 ? -38.742 32.401  -18.548  1.00 52.47  ? 178 ILE I CB  1 
ATOM   9307  C CG1 . ILE E 1 178 ? -40.142 32.601  -19.133  1.00 51.10  ? 178 ILE I CG1 1 
ATOM   9308  C CG2 . ILE E 1 178 ? -38.524 33.316  -17.354  1.00 41.09  ? 178 ILE I CG2 1 
ATOM   9309  C CD1 . ILE E 1 178 ? -41.258 32.383  -18.136  1.00 59.45  ? 178 ILE I CD1 1 
ATOM   9310  N N   . LEU E 1 179 ? -35.531 33.453  -18.808  1.00 53.33  ? 179 LEU I N   1 
ATOM   9311  C CA  . LEU E 1 179 ? -34.184 33.350  -18.267  1.00 44.62  ? 179 LEU I CA  1 
ATOM   9312  C C   . LEU E 1 179 ? -34.088 34.106  -16.949  1.00 55.15  ? 179 LEU I C   1 
ATOM   9313  O O   . LEU E 1 179 ? -34.589 35.228  -16.827  1.00 58.83  ? 179 LEU I O   1 
ATOM   9314  C CB  . LEU E 1 179 ? -33.143 33.895  -19.249  1.00 39.57  ? 179 LEU I CB  1 
ATOM   9315  C CG  . LEU E 1 179 ? -33.123 33.279  -20.650  1.00 55.22  ? 179 LEU I CG  1 
ATOM   9316  C CD1 . LEU E 1 179 ? -33.675 34.261  -21.674  1.00 49.18  ? 179 LEU I CD1 1 
ATOM   9317  C CD2 . LEU E 1 179 ? -31.718 32.846  -21.024  1.00 51.82  ? 179 LEU I CD2 1 
ATOM   9318  N N   . TRP E 1 180 ? -33.436 33.484  -15.968  1.00 51.15  ? 180 TRP I N   1 
ATOM   9319  C CA  . TRP E 1 180 ? -33.186 34.091  -14.669  1.00 42.92  ? 180 TRP I CA  1 
ATOM   9320  C C   . TRP E 1 180 ? -31.795 33.666  -14.215  1.00 43.57  ? 180 TRP I C   1 
ATOM   9321  O O   . TRP E 1 180 ? -31.116 32.887  -14.888  1.00 51.89  ? 180 TRP I O   1 
ATOM   9322  C CB  . TRP E 1 180 ? -34.261 33.690  -13.652  1.00 37.55  ? 180 TRP I CB  1 
ATOM   9323  C CG  . TRP E 1 180 ? -34.205 32.243  -13.280  1.00 42.32  ? 180 TRP I CG  1 
ATOM   9324  C CD1 . TRP E 1 180 ? -33.577 31.697  -12.198  1.00 39.90  ? 180 TRP I CD1 1 
ATOM   9325  C CD2 . TRP E 1 180 ? -34.791 31.151  -13.997  1.00 39.61  ? 180 TRP I CD2 1 
ATOM   9326  N NE1 . TRP E 1 180 ? -33.738 30.333  -12.195  1.00 42.93  ? 180 TRP I NE1 1 
ATOM   9327  C CE2 . TRP E 1 180 ? -34.479 29.973  -13.290  1.00 44.23  ? 180 TRP I CE2 1 
ATOM   9328  C CE3 . TRP E 1 180 ? -35.551 31.056  -15.167  1.00 41.06  ? 180 TRP I CE3 1 
ATOM   9329  C CZ2 . TRP E 1 180 ? -34.902 28.715  -13.713  1.00 39.89  ? 180 TRP I CZ2 1 
ATOM   9330  C CZ3 . TRP E 1 180 ? -35.968 29.807  -15.587  1.00 46.22  ? 180 TRP I CZ3 1 
ATOM   9331  C CH2 . TRP E 1 180 ? -35.643 28.654  -14.862  1.00 44.09  ? 180 TRP I CH2 1 
ATOM   9332  N N   . GLY E 1 181 ? -31.367 34.172  -13.061  1.00 41.14  ? 181 GLY I N   1 
ATOM   9333  C CA  . GLY E 1 181 ? -30.017 33.881  -12.617  1.00 34.37  ? 181 GLY I CA  1 
ATOM   9334  C C   . GLY E 1 181 ? -29.846 34.031  -11.122  1.00 48.61  ? 181 GLY I C   1 
ATOM   9335  O O   . GLY E 1 181 ? -30.745 34.478  -10.405  1.00 44.40  ? 181 GLY I O   1 
ATOM   9336  N N   . ILE E 1 182 ? -28.661 33.632  -10.661  1.00 41.73  ? 182 ILE I N   1 
ATOM   9337  C CA  . ILE E 1 182 ? -28.249 33.782  -9.271   1.00 41.42  ? 182 ILE I CA  1 
ATOM   9338  C C   . ILE E 1 182 ? -26.849 34.378  -9.252   1.00 38.47  ? 182 ILE I C   1 
ATOM   9339  O O   . ILE E 1 182 ? -26.007 34.037  -10.090  1.00 42.59  ? 182 ILE I O   1 
ATOM   9340  C CB  . ILE E 1 182 ? -28.288 32.441  -8.507   1.00 44.14  ? 182 ILE I CB  1 
ATOM   9341  C CG1 . ILE E 1 182 ? -27.898 32.645  -7.041   1.00 42.02  ? 182 ILE I CG1 1 
ATOM   9342  C CG2 . ILE E 1 182 ? -27.385 31.406  -9.170   1.00 43.85  ? 182 ILE I CG2 1 
ATOM   9343  C CD1 . ILE E 1 182 ? -28.018 31.399  -6.196   1.00 43.50  ? 182 ILE I CD1 1 
ATOM   9344  N N   . HIS E 1 183 ? -26.604 35.284  -8.314   1.00 45.64  ? 183 HIS I N   1 
ATOM   9345  C CA  . HIS E 1 183 ? -25.309 35.936  -8.192   1.00 44.54  ? 183 HIS I CA  1 
ATOM   9346  C C   . HIS E 1 183 ? -24.527 35.333  -7.034   1.00 45.77  ? 183 HIS I C   1 
ATOM   9347  O O   . HIS E 1 183 ? -25.016 35.297  -5.899   1.00 41.32  ? 183 HIS I O   1 
ATOM   9348  C CB  . HIS E 1 183 ? -25.464 37.440  -7.982   1.00 42.82  ? 183 HIS I CB  1 
ATOM   9349  C CG  . HIS E 1 183 ? -24.196 38.111  -7.559   1.00 46.98  ? 183 HIS I CG  1 
ATOM   9350  N ND1 . HIS E 1 183 ? -24.016 38.639  -6.299   1.00 44.22  ? 183 HIS I ND1 1 
ATOM   9351  C CD2 . HIS E 1 183 ? -23.033 38.313  -8.222   1.00 46.66  ? 183 HIS I CD2 1 
ATOM   9352  C CE1 . HIS E 1 183 ? -22.802 39.150  -6.208   1.00 48.45  ? 183 HIS I CE1 1 
ATOM   9353  N NE2 . HIS E 1 183 ? -22.185 38.965  -7.361   1.00 57.81  ? 183 HIS I NE2 1 
ATOM   9354  N N   . HIS E 1 184 ? -23.313 34.869  -7.323   1.00 48.05  ? 184 HIS I N   1 
ATOM   9355  C CA  . HIS E 1 184 ? -22.412 34.345  -6.302   1.00 50.05  ? 184 HIS I CA  1 
ATOM   9356  C C   . HIS E 1 184 ? -21.519 35.485  -5.822   1.00 51.13  ? 184 HIS I C   1 
ATOM   9357  O O   . HIS E 1 184 ? -20.693 36.000  -6.583   1.00 46.31  ? 184 HIS I O   1 
ATOM   9358  C CB  . HIS E 1 184 ? -21.581 33.188  -6.851   1.00 43.91  ? 184 HIS I CB  1 
ATOM   9359  C CG  . HIS E 1 184 ? -22.398 32.102  -7.479   1.00 45.93  ? 184 HIS I CG  1 
ATOM   9360  N ND1 . HIS E 1 184 ? -23.247 31.294  -6.753   1.00 49.30  ? 184 HIS I ND1 1 
ATOM   9361  C CD2 . HIS E 1 184 ? -22.495 31.688  -8.764   1.00 48.25  ? 184 HIS I CD2 1 
ATOM   9362  C CE1 . HIS E 1 184 ? -23.833 30.432  -7.563   1.00 48.16  ? 184 HIS I CE1 1 
ATOM   9363  N NE2 . HIS E 1 184 ? -23.394 30.649  -8.790   1.00 43.24  ? 184 HIS I NE2 1 
ATOM   9364  N N   . SER E 1 185 ? -21.688 35.879  -4.563   1.00 50.70  ? 185 SER I N   1 
ATOM   9365  C CA  . SER E 1 185 ? -20.911 36.968  -3.995   1.00 52.73  ? 185 SER I CA  1 
ATOM   9366  C C   . SER E 1 185 ? -19.529 36.475  -3.567   1.00 57.67  ? 185 SER I C   1 
ATOM   9367  O O   . SER E 1 185 ? -19.249 35.274  -3.525   1.00 53.46  ? 185 SER I O   1 
ATOM   9368  C CB  . SER E 1 185 ? -21.658 37.597  -2.820   1.00 40.84  ? 185 SER I CB  1 
ATOM   9369  O OG  . SER E 1 185 ? -22.145 36.605  -1.935   1.00 52.52  ? 185 SER I OG  1 
ATOM   9370  N N   . ASN E 1 186 ? -18.659 37.430  -3.236   1.00 49.20  ? 186 ASN I N   1 
ATOM   9371  C CA  . ASN E 1 186 ? -17.244 37.148  -3.025   1.00 50.12  ? 186 ASN I CA  1 
ATOM   9372  C C   . ASN E 1 186 ? -16.895 36.796  -1.584   1.00 63.04  ? 186 ASN I C   1 
ATOM   9373  O O   . ASN E 1 186 ? -15.942 36.040  -1.359   1.00 59.09  ? 186 ASN I O   1 
ATOM   9374  C CB  . ASN E 1 186 ? -16.407 38.349  -3.472   1.00 47.21  ? 186 ASN I CB  1 
ATOM   9375  C CG  . ASN E 1 186 ? -16.518 38.610  -4.959   1.00 57.36  ? 186 ASN I CG  1 
ATOM   9376  O OD1 . ASN E 1 186 ? -16.537 37.677  -5.763   1.00 57.43  ? 186 ASN I OD1 1 
ATOM   9377  N ND2 . ASN E 1 186 ? -16.601 39.880  -5.334   1.00 57.54  ? 186 ASN I ND2 1 
ATOM   9378  N N   . ASN E 1 187 ? -17.623 37.329  -0.606   1.00 45.41  ? 187 ASN I N   1 
ATOM   9379  C CA  . ASN E 1 187 ? -17.347 37.049  0.797    1.00 57.02  ? 187 ASN I CA  1 
ATOM   9380  C C   . ASN E 1 187 ? -18.575 37.423  1.618    1.00 51.43  ? 187 ASN I C   1 
ATOM   9381  O O   . ASN E 1 187 ? -19.580 37.905  1.087    1.00 49.92  ? 187 ASN I O   1 
ATOM   9382  C CB  . ASN E 1 187 ? -16.097 37.791  1.280    1.00 41.15  ? 187 ASN I CB  1 
ATOM   9383  C CG  . ASN E 1 187 ? -16.057 39.227  0.807    1.00 57.75  ? 187 ASN I CG  1 
ATOM   9384  O OD1 . ASN E 1 187 ? -16.892 40.044  1.195    1.00 57.86  ? 187 ASN I OD1 1 
ATOM   9385  N ND2 . ASN E 1 187 ? -15.081 39.543  -0.038   1.00 58.71  ? 187 ASN I ND2 1 
ATOM   9386  N N   . ALA E 1 188 ? -18.482 37.191  2.930    1.00 56.55  ? 188 ALA I N   1 
ATOM   9387  C CA  . ALA E 1 188 ? -19.610 37.453  3.819    1.00 55.50  ? 188 ALA I CA  1 
ATOM   9388  C C   . ALA E 1 188 ? -19.969 38.933  3.848    1.00 53.66  ? 188 ALA I C   1 
ATOM   9389  O O   . ALA E 1 188 ? -21.154 39.290  3.863    1.00 56.55  ? 188 ALA I O   1 
ATOM   9390  C CB  . ALA E 1 188 ? -19.296 36.951  5.228    1.00 49.87  ? 188 ALA I CB  1 
ATOM   9391  N N   . GLU E 1 189 ? -18.962 39.812  3.870    1.00 62.25  ? 189 GLU I N   1 
ATOM   9392  C CA  . GLU E 1 189 ? -19.238 41.245  3.918    1.00 61.53  ? 189 GLU I CA  1 
ATOM   9393  C C   . GLU E 1 189 ? -19.945 41.725  2.656    1.00 57.77  ? 189 GLU I C   1 
ATOM   9394  O O   . GLU E 1 189 ? -20.913 42.490  2.736    1.00 57.05  ? 189 GLU I O   1 
ATOM   9395  C CB  . GLU E 1 189 ? -17.945 42.029  4.137    1.00 72.53  ? 189 GLU I CB  1 
ATOM   9396  C CG  . GLU E 1 189 ? -18.126 43.534  4.006    1.00 87.71  ? 189 GLU I CG  1 
ATOM   9397  C CD  . GLU E 1 189 ? -17.354 44.317  5.049    1.00 101.12 ? 189 GLU I CD  1 
ATOM   9398  O OE1 . GLU E 1 189 ? -16.106 44.323  4.992    1.00 101.98 ? 189 GLU I OE1 1 
ATOM   9399  O OE2 . GLU E 1 189 ? -18.000 44.921  5.931    1.00 108.26 ? 189 GLU I OE2 1 
ATOM   9400  N N   . GLU E 1 190 ? -19.481 41.286  1.481    1.00 50.95  ? 190 GLU I N   1 
ATOM   9401  C CA  . GLU E 1 190 ? -20.139 41.679  0.239    1.00 42.99  ? 190 GLU I CA  1 
ATOM   9402  C C   . GLU E 1 190 ? -21.551 41.115  0.151    1.00 50.03  ? 190 GLU I C   1 
ATOM   9403  O O   . GLU E 1 190 ? -22.437 41.754  -0.429   1.00 60.27  ? 190 GLU I O   1 
ATOM   9404  C CB  . GLU E 1 190 ? -19.308 41.233  -0.966   1.00 46.11  ? 190 GLU I CB  1 
ATOM   9405  C CG  . GLU E 1 190 ? -19.935 41.577  -2.309   1.00 50.27  ? 190 GLU I CG  1 
ATOM   9406  C CD  . GLU E 1 190 ? -19.144 41.036  -3.488   1.00 74.98  ? 190 GLU I CD  1 
ATOM   9407  O OE1 . GLU E 1 190 ? -18.045 41.564  -3.771   1.00 57.73  ? 190 GLU I OE1 1 
ATOM   9408  O OE2 . GLU E 1 190 ? -19.624 40.076  -4.130   1.00 53.11  ? 190 GLU I OE2 1 
ATOM   9409  N N   . GLN E 1 191 ? -21.781 39.927  0.715    1.00 44.39  ? 191 GLN I N   1 
ATOM   9410  C CA  . GLN E 1 191 ? -23.123 39.352  0.714    1.00 48.87  ? 191 GLN I CA  1 
ATOM   9411  C C   . GLN E 1 191 ? -24.102 40.219  1.502    1.00 46.47  ? 191 GLN I C   1 
ATOM   9412  O O   . GLN E 1 191 ? -25.231 40.452  1.058    1.00 53.06  ? 191 GLN I O   1 
ATOM   9413  C CB  . GLN E 1 191 ? -23.081 37.930  1.277    1.00 40.81  ? 191 GLN I CB  1 
ATOM   9414  C CG  . GLN E 1 191 ? -24.448 37.310  1.547    1.00 43.04  ? 191 GLN I CG  1 
ATOM   9415  C CD  . GLN E 1 191 ? -25.231 37.017  0.282    1.00 49.95  ? 191 GLN I CD  1 
ATOM   9416  O OE1 . GLN E 1 191 ? -24.663 36.893  -0.805   1.00 52.29  ? 191 GLN I OE1 1 
ATOM   9417  N NE2 . GLN E 1 191 ? -26.547 36.901  0.418    1.00 52.86  ? 191 GLN I NE2 1 
ATOM   9418  N N   . THR E 1 192 ? -23.689 40.706  2.677    1.00 52.41  ? 192 THR I N   1 
ATOM   9419  C CA  . THR E 1 192 ? -24.576 41.557  3.466    1.00 54.72  ? 192 THR I CA  1 
ATOM   9420  C C   . THR E 1 192 ? -24.701 42.948  2.853    1.00 49.68  ? 192 THR I C   1 
ATOM   9421  O O   . THR E 1 192 ? -25.780 43.549  2.888    1.00 48.83  ? 192 THR I O   1 
ATOM   9422  C CB  . THR E 1 192 ? -24.086 41.655  4.913    1.00 60.13  ? 192 THR I CB  1 
ATOM   9423  O OG1 . THR E 1 192 ? -22.740 42.149  4.939    1.00 70.83  ? 192 THR I OG1 1 
ATOM   9424  C CG2 . THR E 1 192 ? -24.143 40.294  5.594    1.00 47.98  ? 192 THR I CG2 1 
ATOM   9425  N N   . ASN E 1 193 ? -23.609 43.475  2.288    1.00 48.22  ? 193 ASN I N   1 
ATOM   9426  C CA  . ASN E 1 193 ? -23.648 44.815  1.707    1.00 52.15  ? 193 ASN I CA  1 
ATOM   9427  C C   . ASN E 1 193 ? -24.637 44.907  0.554    1.00 50.04  ? 193 ASN I C   1 
ATOM   9428  O O   . ASN E 1 193 ? -25.164 45.990  0.275    1.00 62.17  ? 193 ASN I O   1 
ATOM   9429  C CB  . ASN E 1 193 ? -22.255 45.234  1.228    1.00 46.76  ? 193 ASN I CB  1 
ATOM   9430  C CG  . ASN E 1 193 ? -21.319 45.576  2.371    1.00 63.30  ? 193 ASN I CG  1 
ATOM   9431  O OD1 . ASN E 1 193 ? -21.757 45.849  3.489    1.00 70.43  ? 193 ASN I OD1 1 
ATOM   9432  N ND2 . ASN E 1 193 ? -20.021 45.572  2.092    1.00 66.76  ? 193 ASN I ND2 1 
ATOM   9433  N N   . LEU E 1 194 ? -24.895 43.796  -0.134   1.00 58.14  ? 194 LEU I N   1 
ATOM   9434  C CA  . LEU E 1 194 ? -25.797 43.796  -1.278   1.00 44.55  ? 194 LEU I CA  1 
ATOM   9435  C C   . LEU E 1 194 ? -27.182 43.254  -0.959   1.00 51.85  ? 194 LEU I C   1 
ATOM   9436  O O   . LEU E 1 194 ? -28.163 43.713  -1.553   1.00 57.14  ? 194 LEU I O   1 
ATOM   9437  C CB  . LEU E 1 194 ? -25.199 42.978  -2.430   1.00 56.45  ? 194 LEU I CB  1 
ATOM   9438  C CG  . LEU E 1 194 ? -24.281 43.692  -3.426   1.00 53.74  ? 194 LEU I CG  1 
ATOM   9439  C CD1 . LEU E 1 194 ? -23.018 44.213  -2.754   1.00 54.95  ? 194 LEU I CD1 1 
ATOM   9440  C CD2 . LEU E 1 194 ? -23.933 42.765  -4.580   1.00 48.80  ? 194 LEU I CD2 1 
ATOM   9441  N N   . TYR E 1 195 ? -27.291 42.292  -0.039   1.00 46.20  ? 195 TYR I N   1 
ATOM   9442  C CA  . TYR E 1 195 ? -28.553 41.603  0.197    1.00 57.07  ? 195 TYR I CA  1 
ATOM   9443  C C   . TYR E 1 195 ? -28.976 41.536  1.658    1.00 54.10  ? 195 TYR I C   1 
ATOM   9444  O O   . TYR E 1 195 ? -30.120 41.153  1.923    1.00 63.60  ? 195 TYR I O   1 
ATOM   9445  C CB  . TYR E 1 195 ? -28.490 40.173  -0.366   1.00 51.49  ? 195 TYR I CB  1 
ATOM   9446  C CG  . TYR E 1 195 ? -27.900 40.096  -1.757   1.00 52.15  ? 195 TYR I CG  1 
ATOM   9447  C CD1 . TYR E 1 195 ? -28.618 40.540  -2.862   1.00 40.62  ? 195 TYR I CD1 1 
ATOM   9448  C CD2 . TYR E 1 195 ? -26.624 39.582  -1.966   1.00 51.05  ? 195 TYR I CD2 1 
ATOM   9449  C CE1 . TYR E 1 195 ? -28.083 40.473  -4.136   1.00 43.30  ? 195 TYR I CE1 1 
ATOM   9450  C CE2 . TYR E 1 195 ? -26.081 39.510  -3.236   1.00 46.48  ? 195 TYR I CE2 1 
ATOM   9451  C CZ  . TYR E 1 195 ? -26.814 39.957  -4.317   1.00 50.93  ? 195 TYR I CZ  1 
ATOM   9452  O OH  . TYR E 1 195 ? -26.277 39.890  -5.580   1.00 48.61  ? 195 TYR I OH  1 
ATOM   9453  N N   . LYS E 1 196 ? -28.081 41.823  2.607    1.00 57.10  ? 196 LYS I N   1 
ATOM   9454  C CA  . LYS E 1 196 ? -28.392 41.969  4.029    1.00 56.06  ? 196 LYS I CA  1 
ATOM   9455  C C   . LYS E 1 196 ? -28.722 40.630  4.686    1.00 57.67  ? 196 LYS I C   1 
ATOM   9456  O O   . LYS E 1 196 ? -28.700 40.508  5.915    1.00 79.96  ? 196 LYS I O   1 
ATOM   9457  C CB  . LYS E 1 196 ? -29.546 42.971  4.206    1.00 55.15  ? 196 LYS I CB  1 
ATOM   9458  C CG  . LYS E 1 196 ? -30.151 43.072  5.604    1.00 67.18  ? 196 LYS I CG  1 
ATOM   9459  C CD  . LYS E 1 196 ? -29.126 43.515  6.634    1.00 69.90  ? 196 LYS I CD  1 
ATOM   9460  C CE  . LYS E 1 196 ? -29.776 43.759  7.984    1.00 73.51  ? 196 LYS I CE  1 
ATOM   9461  N NZ  . LYS E 1 196 ? -28.828 44.375  8.954    1.00 84.88  ? 196 LYS I NZ  1 
ATOM   9462  N N   . ASN E 1 197 ? -28.930 39.592  3.885    1.00 58.62  ? 197 ASN I N   1 
ATOM   9463  C CA  . ASN E 1 197 ? -29.250 38.275  4.415    1.00 55.33  ? 197 ASN I CA  1 
ATOM   9464  C C   . ASN E 1 197 ? -28.040 37.375  4.243    1.00 51.46  ? 197 ASN I C   1 
ATOM   9465  O O   . ASN E 1 197 ? -27.624 37.130  3.101    1.00 55.18  ? 197 ASN I O   1 
ATOM   9466  C CB  . ASN E 1 197 ? -30.465 37.682  3.706    1.00 62.82  ? 197 ASN I CB  1 
ATOM   9467  C CG  . ASN E 1 197 ? -31.738 38.462  3.979    1.00 68.06  ? 197 ASN I CG  1 
ATOM   9468  O OD1 . ASN E 1 197 ? -31.973 38.919  5.098    1.00 69.01  ? 197 ASN I OD1 1 
ATOM   9469  N ND2 . ASN E 1 197 ? -32.568 38.619  2.953    1.00 52.65  ? 197 ASN I ND2 1 
ATOM   9470  N N   . PRO E 1 198 ? -27.427 36.892  5.327    1.00 59.21  ? 198 PRO I N   1 
ATOM   9471  C CA  . PRO E 1 198 ? -26.215 36.072  5.164    1.00 58.74  ? 198 PRO I CA  1 
ATOM   9472  C C   . PRO E 1 198 ? -26.450 34.791  4.381    1.00 46.57  ? 198 PRO I C   1 
ATOM   9473  O O   . PRO E 1 198 ? -25.624 34.429  3.535    1.00 59.45  ? 198 PRO I O   1 
ATOM   9474  C CB  . PRO E 1 198 ? -25.791 35.788  6.612    1.00 45.75  ? 198 PRO I CB  1 
ATOM   9475  C CG  . PRO E 1 198 ? -27.052 35.919  7.409    1.00 69.23  ? 198 PRO I CG  1 
ATOM   9476  C CD  . PRO E 1 198 ? -27.851 36.995  6.734    1.00 58.96  ? 198 PRO I CD  1 
ATOM   9477  N N   . ILE E 1 199 ? -27.566 34.108  4.622    1.00 55.28  ? 199 ILE I N   1 
ATOM   9478  C CA  . ILE E 1 199 ? -27.853 32.806  4.029    1.00 58.13  ? 199 ILE I CA  1 
ATOM   9479  C C   . ILE E 1 199 ? -29.126 32.938  3.207    1.00 44.25  ? 199 ILE I C   1 
ATOM   9480  O O   . ILE E 1 199 ? -30.194 33.241  3.754    1.00 67.01  ? 199 ILE I O   1 
ATOM   9481  C CB  . ILE E 1 199 ? -27.999 31.720  5.105    1.00 58.02  ? 199 ILE I CB  1 
ATOM   9482  C CG1 . ILE E 1 199 ? -26.688 31.573  5.882    1.00 61.78  ? 199 ILE I CG1 1 
ATOM   9483  C CG2 . ILE E 1 199 ? -28.417 30.400  4.479    1.00 55.39  ? 199 ILE I CG2 1 
ATOM   9484  C CD1 . ILE E 1 199 ? -26.853 30.970  7.258    1.00 78.04  ? 199 ILE I CD1 1 
ATOM   9485  N N   . THR E 1 200 ? -29.018 32.709  1.899    1.00 50.81  ? 200 THR I N   1 
ATOM   9486  C CA  . THR E 1 200 ? -30.102 32.989  0.966    1.00 55.81  ? 200 THR I CA  1 
ATOM   9487  C C   . THR E 1 200 ? -30.310 31.813  0.020    1.00 50.20  ? 200 THR I C   1 
ATOM   9488  O O   . THR E 1 200 ? -29.474 30.912  -0.091   1.00 50.36  ? 200 THR I O   1 
ATOM   9489  C CB  . THR E 1 200 ? -29.830 34.256  0.146    1.00 51.42  ? 200 THR I CB  1 
ATOM   9490  O OG1 . THR E 1 200 ? -28.699 34.039  -0.705   1.00 42.81  ? 200 THR I OG1 1 
ATOM   9491  C CG2 . THR E 1 200 ? -29.551 35.441  1.057    1.00 47.81  ? 200 THR I CG2 1 
ATOM   9492  N N   . TYR E 1 201 ? -31.440 31.850  -0.684   1.00 50.93  ? 201 TYR I N   1 
ATOM   9493  C CA  . TYR E 1 201 ? -31.818 30.795  -1.611   1.00 50.07  ? 201 TYR I CA  1 
ATOM   9494  C C   . TYR E 1 201 ? -32.641 31.395  -2.743   1.00 52.45  ? 201 TYR I C   1 
ATOM   9495  O O   . TYR E 1 201 ? -33.078 32.548  -2.682   1.00 55.14  ? 201 TYR I O   1 
ATOM   9496  C CB  . TYR E 1 201 ? -32.616 29.693  -0.909   1.00 64.18  ? 201 TYR I CB  1 
ATOM   9497  C CG  . TYR E 1 201 ? -33.989 30.149  -0.466   1.00 57.46  ? 201 TYR I CG  1 
ATOM   9498  C CD1 . TYR E 1 201 ? -34.162 30.827  0.732    1.00 62.32  ? 201 TYR I CD1 1 
ATOM   9499  C CD2 . TYR E 1 201 ? -35.109 29.912  -1.252   1.00 54.33  ? 201 TYR I CD2 1 
ATOM   9500  C CE1 . TYR E 1 201 ? -35.413 31.251  1.139    1.00 68.53  ? 201 TYR I CE1 1 
ATOM   9501  C CE2 . TYR E 1 201 ? -36.362 30.333  -0.855   1.00 62.58  ? 201 TYR I CE2 1 
ATOM   9502  C CZ  . TYR E 1 201 ? -36.508 31.002  0.342    1.00 61.40  ? 201 TYR I CZ  1 
ATOM   9503  O OH  . TYR E 1 201 ? -37.753 31.425  0.746    1.00 75.35  ? 201 TYR I OH  1 
ATOM   9504  N N   . ILE E 1 202 ? -32.846 30.592  -3.785   1.00 48.79  ? 202 ILE I N   1 
ATOM   9505  C CA  . ILE E 1 202 ? -33.766 30.908  -4.873   1.00 47.08  ? 202 ILE I CA  1 
ATOM   9506  C C   . ILE E 1 202 ? -34.562 29.650  -5.191   1.00 49.92  ? 202 ILE I C   1 
ATOM   9507  O O   . ILE E 1 202 ? -33.980 28.576  -5.373   1.00 53.81  ? 202 ILE I O   1 
ATOM   9508  C CB  . ILE E 1 202 ? -33.033 31.407  -6.134   1.00 46.21  ? 202 ILE I CB  1 
ATOM   9509  C CG1 . ILE E 1 202 ? -32.331 32.736  -5.864   1.00 45.43  ? 202 ILE I CG1 1 
ATOM   9510  C CG2 . ILE E 1 202 ? -34.004 31.554  -7.293   1.00 39.58  ? 202 ILE I CG2 1 
ATOM   9511  C CD1 . ILE E 1 202 ? -31.514 33.228  -7.028   1.00 46.95  ? 202 ILE I CD1 1 
ATOM   9512  N N   . SER E 1 203 ? -35.886 29.777  -5.254   1.00 51.68  ? 203 SER I N   1 
ATOM   9513  C CA  . SER E 1 203 ? -36.767 28.676  -5.626   1.00 46.85  ? 203 SER I CA  1 
ATOM   9514  C C   . SER E 1 203 ? -37.544 29.056  -6.878   1.00 53.23  ? 203 SER I C   1 
ATOM   9515  O O   . SER E 1 203 ? -38.127 30.142  -6.946   1.00 49.53  ? 203 SER I O   1 
ATOM   9516  C CB  . SER E 1 203 ? -37.730 28.324  -4.488   1.00 51.00  ? 203 SER I CB  1 
ATOM   9517  O OG  . SER E 1 203 ? -37.029 27.847  -3.353   1.00 59.64  ? 203 SER I OG  1 
ATOM   9518  N N   . VAL E 1 204 ? -37.543 28.167  -7.868   1.00 48.30  ? 204 VAL I N   1 
ATOM   9519  C CA  . VAL E 1 204 ? -38.260 28.381  -9.118   1.00 47.52  ? 204 VAL I CA  1 
ATOM   9520  C C   . VAL E 1 204 ? -39.132 27.162  -9.379   1.00 51.25  ? 204 VAL I C   1 
ATOM   9521  O O   . VAL E 1 204 ? -38.637 26.030  -9.374   1.00 51.29  ? 204 VAL I O   1 
ATOM   9522  C CB  . VAL E 1 204 ? -37.300 28.625  -10.299  1.00 50.18  ? 204 VAL I CB  1 
ATOM   9523  C CG1 . VAL E 1 204 ? -38.075 29.093  -11.520  1.00 46.91  ? 204 VAL I CG1 1 
ATOM   9524  C CG2 . VAL E 1 204 ? -36.231 29.641  -9.922   1.00 48.50  ? 204 VAL I CG2 1 
ATOM   9525  N N   . GLY E 1 205 ? -40.414 27.391  -9.609   1.00 61.53  ? 205 GLY I N   1 
ATOM   9526  C CA  . GLY E 1 205 ? -41.359 26.302  -9.800   1.00 49.53  ? 205 GLY I CA  1 
ATOM   9527  C C   . GLY E 1 205 ? -42.277 26.535  -10.978  1.00 45.78  ? 205 GLY I C   1 
ATOM   9528  O O   . GLY E 1 205 ? -42.769 27.643  -11.190  1.00 47.86  ? 205 GLY I O   1 
ATOM   9529  N N   . THR E 1 206 ? -42.495 25.475  -11.748  1.00 41.20  ? 206 THR I N   1 
ATOM   9530  C CA  . THR E 1 206 ? -43.469 25.454  -12.836  1.00 51.43  ? 206 THR I CA  1 
ATOM   9531  C C   . THR E 1 206 ? -44.179 24.108  -12.750  1.00 47.73  ? 206 THR I C   1 
ATOM   9532  O O   . THR E 1 206 ? -44.121 23.417  -11.727  1.00 60.44  ? 206 THR I O   1 
ATOM   9533  C CB  . THR E 1 206 ? -42.816 25.669  -14.214  1.00 46.41  ? 206 THR I CB  1 
ATOM   9534  O OG1 . THR E 1 206 ? -42.025 24.524  -14.561  1.00 49.75  ? 206 THR I OG1 1 
ATOM   9535  C CG2 . THR E 1 206 ? -41.940 26.912  -14.231  1.00 50.04  ? 206 THR I CG2 1 
ATOM   9536  N N   . SER E 1 207 ? -44.868 23.717  -13.822  1.00 52.43  ? 207 SER I N   1 
ATOM   9537  C CA  . SER E 1 207 ? -45.457 22.385  -13.847  1.00 59.26  ? 207 SER I CA  1 
ATOM   9538  C C   . SER E 1 207 ? -44.398 21.288  -13.913  1.00 55.20  ? 207 SER I C   1 
ATOM   9539  O O   . SER E 1 207 ? -44.696 20.139  -13.567  1.00 60.11  ? 207 SER I O   1 
ATOM   9540  C CB  . SER E 1 207 ? -46.426 22.254  -15.024  1.00 50.81  ? 207 SER I CB  1 
ATOM   9541  O OG  . SER E 1 207 ? -45.740 22.200  -16.263  1.00 61.46  ? 207 SER I OG  1 
ATOM   9542  N N   . THR E 1 208 ? -43.174 21.608  -14.340  1.00 61.23  ? 208 THR I N   1 
ATOM   9543  C CA  . THR E 1 208 ? -42.140 20.587  -14.474  1.00 64.76  ? 208 THR I CA  1 
ATOM   9544  C C   . THR E 1 208 ? -40.869 20.953  -13.711  1.00 59.32  ? 208 THR I C   1 
ATOM   9545  O O   . THR E 1 208 ? -40.137 20.069  -13.249  1.00 63.05  ? 208 THR I O   1 
ATOM   9546  C CB  . THR E 1 208 ? -41.806 20.343  -15.948  1.00 57.67  ? 208 THR I CB  1 
ATOM   9547  O OG1 . THR E 1 208 ? -41.387 21.571  -16.554  1.00 55.67  ? 208 THR I OG1 1 
ATOM   9548  C CG2 . THR E 1 208 ? -43.016 19.795  -16.692  1.00 47.23  ? 208 THR I CG2 1 
ATOM   9549  N N   . LEU E 1 209 ? -40.591 22.246  -13.572  1.00 51.66  ? 209 LEU I N   1 
ATOM   9550  C CA  . LEU E 1 209 ? -39.354 22.705  -12.955  1.00 48.04  ? 209 LEU I CA  1 
ATOM   9551  C C   . LEU E 1 209 ? -39.518 22.796  -11.441  1.00 53.11  ? 209 LEU I C   1 
ATOM   9552  O O   . LEU E 1 209 ? -40.503 23.355  -10.948  1.00 53.07  ? 209 LEU I O   1 
ATOM   9553  C CB  . LEU E 1 209 ? -38.942 24.062  -13.526  1.00 55.09  ? 209 LEU I CB  1 
ATOM   9554  C CG  . LEU E 1 209 ? -37.604 24.638  -13.051  1.00 53.54  ? 209 LEU I CG  1 
ATOM   9555  C CD1 . LEU E 1 209 ? -36.433 23.843  -13.608  1.00 38.57  ? 209 LEU I CD1 1 
ATOM   9556  C CD2 . LEU E 1 209 ? -37.492 26.096  -13.431  1.00 47.85  ? 209 LEU I CD2 1 
ATOM   9557  N N   . ASN E 1 210 ? -38.557 22.223  -10.709  1.00 45.70  ? 210 ASN I N   1 
ATOM   9558  C CA  . ASN E 1 210 ? -38.502 22.300  -9.245   1.00 54.43  ? 210 ASN I CA  1 
ATOM   9559  C C   . ASN E 1 210 ? -37.048 22.588  -8.869   1.00 54.21  ? 210 ASN I C   1 
ATOM   9560  O O   . ASN E 1 210 ? -36.280 21.670  -8.568   1.00 62.47  ? 210 ASN I O   1 
ATOM   9561  C CB  . ASN E 1 210 ? -39.014 21.009  -8.614   1.00 51.18  ? 210 ASN I CB  1 
ATOM   9562  C CG  . ASN E 1 210 ? -39.126 21.095  -7.105   1.00 55.62  ? 210 ASN I CG  1 
ATOM   9563  O OD1 . ASN E 1 210 ? -39.211 22.184  -6.535   1.00 52.23  ? 210 ASN I OD1 1 
ATOM   9564  N ND2 . ASN E 1 210 ? -39.134 19.941  -6.448   1.00 54.91  ? 210 ASN I ND2 1 
ATOM   9565  N N   . GLN E 1 211 ? -36.684 23.869  -8.853   1.00 45.49  ? 211 GLN I N   1 
ATOM   9566  C CA  . GLN E 1 211 ? -35.294 24.290  -8.725   1.00 41.50  ? 211 GLN I CA  1 
ATOM   9567  C C   . GLN E 1 211 ? -35.069 25.011  -7.404   1.00 44.43  ? 211 GLN I C   1 
ATOM   9568  O O   . GLN E 1 211 ? -35.866 25.872  -7.017   1.00 53.52  ? 211 GLN I O   1 
ATOM   9569  C CB  . GLN E 1 211 ? -34.891 25.202  -9.885   1.00 35.28  ? 211 GLN I CB  1 
ATOM   9570  C CG  . GLN E 1 211 ? -33.469 25.734  -9.780   1.00 41.32  ? 211 GLN I CG  1 
ATOM   9571  C CD  . GLN E 1 211 ? -33.089 26.642  -10.937  1.00 64.74  ? 211 GLN I CD  1 
ATOM   9572  O OE1 . GLN E 1 211 ? -33.307 27.854  -10.890  1.00 57.31  ? 211 GLN I OE1 1 
ATOM   9573  N NE2 . GLN E 1 211 ? -32.511 26.058  -11.981  1.00 51.24  ? 211 GLN I NE2 1 
ATOM   9574  N N   . ARG E 1 212 ? -33.984 24.659  -6.717   1.00 43.39  ? 212 ARG I N   1 
ATOM   9575  C CA  . ARG E 1 212 ? -33.527 25.385  -5.540   1.00 40.35  ? 212 ARG I CA  1 
ATOM   9576  C C   . ARG E 1 212 ? -32.046 25.685  -5.707   1.00 55.14  ? 212 ARG I C   1 
ATOM   9577  O O   . ARG E 1 212 ? -31.246 24.767  -5.915   1.00 47.56  ? 212 ARG I O   1 
ATOM   9578  C CB  . ARG E 1 212 ? -33.776 24.591  -4.256   1.00 53.43  ? 212 ARG I CB  1 
ATOM   9579  C CG  . ARG E 1 212 ? -33.526 25.409  -3.001   1.00 61.03  ? 212 ARG I CG  1 
ATOM   9580  C CD  . ARG E 1 212 ? -33.945 24.668  -1.749   1.00 76.67  ? 212 ARG I CD  1 
ATOM   9581  N NE  . ARG E 1 212 ? -34.221 25.590  -0.655   1.00 82.20  ? 212 ARG I NE  1 
ATOM   9582  C CZ  . ARG E 1 212 ? -33.292 26.135  0.120    1.00 82.43  ? 212 ARG I CZ  1 
ATOM   9583  N NH1 . ARG E 1 212 ? -32.006 25.877  -0.056   1.00 79.27  ? 212 ARG I NH1 1 
ATOM   9584  N NH2 . ARG E 1 212 ? -33.663 26.961  1.094    1.00 72.97  ? 212 ARG I NH2 1 
ATOM   9585  N N   . LEU E 1 213 ? -31.681 26.962  -5.599   1.00 48.64  ? 213 LEU I N   1 
ATOM   9586  C CA  . LEU E 1 213 ? -30.308 27.412  -5.773   1.00 46.72  ? 213 LEU I CA  1 
ATOM   9587  C C   . LEU E 1 213 ? -29.841 28.148  -4.526   1.00 50.42  ? 213 LEU I C   1 
ATOM   9588  O O   . LEU E 1 213 ? -30.611 28.888  -3.908   1.00 51.00  ? 213 LEU I O   1 
ATOM   9589  C CB  . LEU E 1 213 ? -30.172 28.342  -6.984   1.00 43.42  ? 213 LEU I CB  1 
ATOM   9590  C CG  . LEU E 1 213 ? -30.692 27.884  -8.345   1.00 55.98  ? 213 LEU I CG  1 
ATOM   9591  C CD1 . LEU E 1 213 ? -30.736 29.070  -9.294   1.00 53.72  ? 213 LEU I CD1 1 
ATOM   9592  C CD2 . LEU E 1 213 ? -29.823 26.774  -8.914   1.00 51.83  ? 213 LEU I CD2 1 
ATOM   9593  N N   . ALA E 1 214 ? -28.575 27.950  -4.168   1.00 45.88  ? 214 ALA I N   1 
ATOM   9594  C CA  . ALA E 1 214 ? -27.951 28.707  -3.099   1.00 43.37  ? 214 ALA I CA  1 
ATOM   9595  C C   . ALA E 1 214 ? -26.657 29.323  -3.611   1.00 47.90  ? 214 ALA I C   1 
ATOM   9596  O O   . ALA E 1 214 ? -25.955 28.708  -4.424   1.00 46.78  ? 214 ALA I O   1 
ATOM   9597  C CB  . ALA E 1 214 ? -27.657 27.822  -1.878   1.00 42.23  ? 214 ALA I CB  1 
ATOM   9598  N N   . PRO E 1 215 ? -26.320 30.531  -3.164   1.00 51.76  ? 215 PRO I N   1 
ATOM   9599  C CA  . PRO E 1 215 ? -25.084 31.165  -3.630   1.00 47.91  ? 215 PRO I CA  1 
ATOM   9600  C C   . PRO E 1 215 ? -23.856 30.416  -3.144   1.00 46.91  ? 215 PRO I C   1 
ATOM   9601  O O   . PRO E 1 215 ? -23.830 29.854  -2.047   1.00 54.74  ? 215 PRO I O   1 
ATOM   9602  C CB  . PRO E 1 215 ? -25.149 32.572  -3.021   1.00 47.92  ? 215 PRO I CB  1 
ATOM   9603  C CG  . PRO E 1 215 ? -26.575 32.757  -2.612   1.00 49.36  ? 215 PRO I CG  1 
ATOM   9604  C CD  . PRO E 1 215 ? -27.069 31.399  -2.243   1.00 48.03  ? 215 PRO I CD  1 
ATOM   9605  N N   . LYS E 1 216 ? -22.825 30.422  -3.980   1.00 50.57  ? 216 LYS I N   1 
ATOM   9606  C CA  . LYS E 1 216 ? -21.533 29.835  -3.645   1.00 50.03  ? 216 LYS I CA  1 
ATOM   9607  C C   . LYS E 1 216 ? -20.584 30.989  -3.345   1.00 47.87  ? 216 LYS I C   1 
ATOM   9608  O O   . LYS E 1 216 ? -20.008 31.592  -4.253   1.00 48.24  ? 216 LYS I O   1 
ATOM   9609  C CB  . LYS E 1 216 ? -21.032 28.941  -4.776   1.00 47.45  ? 216 LYS I CB  1 
ATOM   9610  C CG  . LYS E 1 216 ? -21.800 27.625  -4.873   1.00 52.76  ? 216 LYS I CG  1 
ATOM   9611  C CD  . LYS E 1 216 ? -21.321 26.748  -6.018   1.00 48.29  ? 216 LYS I CD  1 
ATOM   9612  C CE  . LYS E 1 216 ? -21.969 27.145  -7.334   1.00 61.48  ? 216 LYS I CE  1 
ATOM   9613  N NZ  . LYS E 1 216 ? -21.733 26.121  -8.393   1.00 55.56  ? 216 LYS I NZ  1 
ATOM   9614  N N   . ILE E 1 217 ? -20.439 31.302  -2.062   1.00 50.46  ? 217 ILE I N   1 
ATOM   9615  C CA  . ILE E 1 217 ? -19.638 32.434  -1.614   1.00 55.49  ? 217 ILE I CA  1 
ATOM   9616  C C   . ILE E 1 217 ? -18.212 31.939  -1.404   1.00 61.29  ? 217 ILE I C   1 
ATOM   9617  O O   . ILE E 1 217 ? -17.923 31.245  -0.426   1.00 61.15  ? 217 ILE I O   1 
ATOM   9618  C CB  . ILE E 1 217 ? -20.214 33.052  -0.336   1.00 49.79  ? 217 ILE I CB  1 
ATOM   9619  C CG1 . ILE E 1 217 ? -21.667 33.477  -0.569   1.00 51.95  ? 217 ILE I CG1 1 
ATOM   9620  C CG2 . ILE E 1 217 ? -19.378 34.234  0.106    1.00 48.85  ? 217 ILE I CG2 1 
ATOM   9621  C CD1 . ILE E 1 217 ? -22.314 34.136  0.629    1.00 52.26  ? 217 ILE I CD1 1 
ATOM   9622  N N   . ALA E 1 218 ? -17.319 32.300  -2.322   1.00 53.56  ? 218 ALA I N   1 
ATOM   9623  C CA  . ALA E 1 218 ? -15.968 31.758  -2.322   1.00 62.47  ? 218 ALA I CA  1 
ATOM   9624  C C   . ALA E 1 218 ? -15.043 32.718  -3.056   1.00 51.88  ? 218 ALA I C   1 
ATOM   9625  O O   . ALA E 1 218 ? -15.486 33.645  -3.738   1.00 49.15  ? 218 ALA I O   1 
ATOM   9626  C CB  . ALA E 1 218 ? -15.930 30.368  -2.964   1.00 49.06  ? 218 ALA I CB  1 
ATOM   9627  N N   . THR E 1 219 ? -13.744 32.477  -2.901   1.00 61.09  ? 219 THR I N   1 
ATOM   9628  C CA  . THR E 1 219 ? -12.729 33.230  -3.624   1.00 47.42  ? 219 THR I CA  1 
ATOM   9629  C C   . THR E 1 219 ? -12.573 32.666  -5.030   1.00 52.56  ? 219 THR I C   1 
ATOM   9630  O O   . THR E 1 219 ? -12.412 31.455  -5.207   1.00 49.36  ? 219 THR I O   1 
ATOM   9631  C CB  . THR E 1 219 ? -11.394 33.173  -2.882   1.00 40.50  ? 219 THR I CB  1 
ATOM   9632  O OG1 . THR E 1 219 ? -11.561 33.693  -1.556   1.00 57.47  ? 219 THR I OG1 1 
ATOM   9633  C CG2 . THR E 1 219 ? -10.338 33.987  -3.617   1.00 47.66  ? 219 THR I CG2 1 
ATOM   9634  N N   . ARG E 1 220 ? -12.622 33.545  -6.028   1.00 49.56  ? 220 ARG I N   1 
ATOM   9635  C CA  . ARG E 1 220 ? -12.467 33.159  -7.421   1.00 43.94  ? 220 ARG I CA  1 
ATOM   9636  C C   . ARG E 1 220 ? -11.518 34.129  -8.112   1.00 42.46  ? 220 ARG I C   1 
ATOM   9637  O O   . ARG E 1 220 ? -11.222 35.212  -7.602   1.00 56.84  ? 220 ARG I O   1 
ATOM   9638  C CB  . ARG E 1 220 ? -13.816 33.128  -8.153   1.00 46.37  ? 220 ARG I CB  1 
ATOM   9639  C CG  . ARG E 1 220 ? -14.734 31.991  -7.730   1.00 53.80  ? 220 ARG I CG  1 
ATOM   9640  C CD  . ARG E 1 220 ? -16.158 32.251  -8.180   1.00 43.01  ? 220 ARG I CD  1 
ATOM   9641  N NE  . ARG E 1 220 ? -16.696 33.453  -7.556   1.00 54.14  ? 220 ARG I NE  1 
ATOM   9642  C CZ  . ARG E 1 220 ? -17.526 33.454  -6.522   1.00 54.03  ? 220 ARG I CZ  1 
ATOM   9643  N NH1 . ARG E 1 220 ? -17.982 32.328  -6.000   1.00 45.79  ? 220 ARG I NH1 1 
ATOM   9644  N NH2 . ARG E 1 220 ? -17.911 34.616  -6.001   1.00 45.96  ? 220 ARG I NH2 1 
ATOM   9645  N N   . SER E 1 221 ? -11.031 33.718  -9.278   1.00 44.48  ? 221 SER I N   1 
ATOM   9646  C CA  . SER E 1 221 ? -10.170 34.568  -10.082  1.00 48.57  ? 221 SER I CA  1 
ATOM   9647  C C   . SER E 1 221 ? -10.987 35.653  -10.779  1.00 52.93  ? 221 SER I C   1 
ATOM   9648  O O   . SER E 1 221 ? -12.195 35.522  -10.993  1.00 57.92  ? 221 SER I O   1 
ATOM   9649  C CB  . SER E 1 221 ? -9.404  33.742  -11.116  1.00 40.98  ? 221 SER I CB  1 
ATOM   9650  O OG  . SER E 1 221 ? -8.582  32.774  -10.488  1.00 52.41  ? 221 SER I OG  1 
ATOM   9651  N N   . GLN E 1 222 ? -10.304 36.735  -11.139  1.00 42.59  ? 222 GLN I N   1 
ATOM   9652  C CA  . GLN E 1 222 ? -10.954 37.867  -11.785  1.00 56.93  ? 222 GLN I CA  1 
ATOM   9653  C C   . GLN E 1 222 ? -11.157 37.595  -13.270  1.00 62.22  ? 222 GLN I C   1 
ATOM   9654  O O   . GLN E 1 222 ? -10.219 37.217  -13.979  1.00 54.95  ? 222 GLN I O   1 
ATOM   9655  C CB  . GLN E 1 222 ? -10.127 39.138  -11.592  1.00 42.39  ? 222 GLN I CB  1 
ATOM   9656  C CG  . GLN E 1 222 ? -10.671 40.075  -10.527  1.00 64.96  ? 222 GLN I CG  1 
ATOM   9657  C CD  . GLN E 1 222 ? -9.728  41.223  -10.221  1.00 68.09  ? 222 GLN I CD  1 
ATOM   9658  O OE1 . GLN E 1 222 ? -8.509  41.079  -10.307  1.00 65.31  ? 222 GLN I OE1 1 
ATOM   9659  N NE2 . GLN E 1 222 ? -10.290 42.373  -9.861   1.00 64.30  ? 222 GLN I NE2 1 
ATOM   9660  N N   . VAL E 1 223 ? -12.390 37.779  -13.732  1.00 50.96  ? 223 VAL I N   1 
ATOM   9661  C CA  . VAL E 1 223 ? -12.731 37.754  -15.147  1.00 44.75  ? 223 VAL I CA  1 
ATOM   9662  C C   . VAL E 1 223 ? -13.491 39.036  -15.450  1.00 56.82  ? 223 VAL I C   1 
ATOM   9663  O O   . VAL E 1 223 ? -14.468 39.356  -14.763  1.00 48.72  ? 223 VAL I O   1 
ATOM   9664  C CB  . VAL E 1 223 ? -13.572 36.517  -15.518  1.00 51.23  ? 223 VAL I CB  1 
ATOM   9665  C CG1 . VAL E 1 223 ? -13.857 36.494  -17.012  1.00 39.44  ? 223 VAL I CG1 1 
ATOM   9666  C CG2 . VAL E 1 223 ? -12.863 35.240  -15.079  1.00 43.74  ? 223 VAL I CG2 1 
ATOM   9667  N N   . ASN E 1 224 ? -13.030 39.776  -16.459  1.00 64.04  ? 224 ASN I N   1 
ATOM   9668  C CA  . ASN E 1 224 ? -13.558 41.110  -16.760  1.00 50.35  ? 224 ASN I CA  1 
ATOM   9669  C C   . ASN E 1 224 ? -13.526 41.996  -15.516  1.00 44.34  ? 224 ASN I C   1 
ATOM   9670  O O   . ASN E 1 224 ? -14.406 42.832  -15.291  1.00 55.71  ? 224 ASN I O   1 
ATOM   9671  C CB  . ASN E 1 224 ? -14.967 41.029  -17.349  1.00 49.19  ? 224 ASN I CB  1 
ATOM   9672  C CG  . ASN E 1 224 ? -14.996 40.339  -18.701  1.00 49.00  ? 224 ASN I CG  1 
ATOM   9673  O OD1 . ASN E 1 224 ? -14.070 40.476  -19.498  1.00 57.85  ? 224 ASN I OD1 1 
ATOM   9674  N ND2 . ASN E 1 224 ? -16.059 39.586  -18.961  1.00 53.74  ? 224 ASN I ND2 1 
ATOM   9675  N N   . GLY E 1 225 ? -12.499 41.797  -14.692  1.00 53.29  ? 225 GLY I N   1 
ATOM   9676  C CA  . GLY E 1 225 ? -12.295 42.589  -13.497  1.00 46.78  ? 225 GLY I CA  1 
ATOM   9677  C C   . GLY E 1 225 ? -13.151 42.220  -12.306  1.00 63.22  ? 225 GLY I C   1 
ATOM   9678  O O   . GLY E 1 225 ? -13.119 42.939  -11.301  1.00 56.66  ? 225 GLY I O   1 
ATOM   9679  N N   . GLN E 1 226 ? -13.912 41.128  -12.376  1.00 54.41  ? 226 GLN I N   1 
ATOM   9680  C CA  . GLN E 1 226 ? -14.843 40.761  -11.315  1.00 47.89  ? 226 GLN I CA  1 
ATOM   9681  C C   . GLN E 1 226 ? -14.576 39.342  -10.834  1.00 49.30  ? 226 GLN I C   1 
ATOM   9682  O O   . GLN E 1 226 ? -14.457 38.418  -11.644  1.00 44.04  ? 226 GLN I O   1 
ATOM   9683  C CB  . GLN E 1 226 ? -16.295 40.889  -11.791  1.00 43.46  ? 226 GLN I CB  1 
ATOM   9684  C CG  . GLN E 1 226 ? -16.699 42.312  -12.113  1.00 42.22  ? 226 GLN I CG  1 
ATOM   9685  C CD  . GLN E 1 226 ? -16.470 43.249  -10.944  1.00 56.01  ? 226 GLN I CD  1 
ATOM   9686  O OE1 . GLN E 1 226 ? -16.792 42.921  -9.801   1.00 54.63  ? 226 GLN I OE1 1 
ATOM   9687  N NE2 . GLN E 1 226 ? -15.906 44.419  -11.222  1.00 60.76  ? 226 GLN I NE2 1 
ATOM   9688  N N   . ARG E 1 227 ? -14.488 39.174  -9.515   1.00 46.79  ? 227 ARG I N   1 
ATOM   9689  C CA  . ARG E 1 227 ? -14.393 37.855  -8.909   1.00 48.15  ? 227 ARG I CA  1 
ATOM   9690  C C   . ARG E 1 227 ? -15.754 37.214  -8.672   1.00 53.12  ? 227 ARG I C   1 
ATOM   9691  O O   . ARG E 1 227 ? -15.818 36.007  -8.406   1.00 45.02  ? 227 ARG I O   1 
ATOM   9692  C CB  . ARG E 1 227 ? -13.622 37.936  -7.585   1.00 45.99  ? 227 ARG I CB  1 
ATOM   9693  C CG  . ARG E 1 227 ? -12.176 38.376  -7.756   1.00 44.68  ? 227 ARG I CG  1 
ATOM   9694  C CD  . ARG E 1 227 ? -11.433 38.449  -6.432   1.00 42.02  ? 227 ARG I CD  1 
ATOM   9695  N NE  . ARG E 1 227 ? -10.076 38.948  -6.615   1.00 56.38  ? 227 ARG I NE  1 
ATOM   9696  C CZ  . ARG E 1 227 ? -9.041  38.195  -6.965   1.00 55.49  ? 227 ARG I CZ  1 
ATOM   9697  N NH1 . ARG E 1 227 ? -9.170  36.894  -7.165   1.00 59.50  ? 227 ARG I NH1 1 
ATOM   9698  N NH2 . ARG E 1 227 ? -7.849  38.763  -7.122   1.00 57.77  ? 227 ARG I NH2 1 
ATOM   9699  N N   . GLY E 1 228 ? -16.839 37.984  -8.763   1.00 42.36  ? 228 GLY I N   1 
ATOM   9700  C CA  . GLY E 1 228 ? -18.164 37.418  -8.644   1.00 43.55  ? 228 GLY I CA  1 
ATOM   9701  C C   . GLY E 1 228 ? -18.574 36.664  -9.889   1.00 50.85  ? 228 GLY I C   1 
ATOM   9702  O O   . GLY E 1 228 ? -17.952 36.767  -10.945  1.00 48.78  ? 228 GLY I O   1 
ATOM   9703  N N   . ARG E 1 229 ? -19.644 35.883  -9.753   1.00 45.21  ? 229 ARG I N   1 
ATOM   9704  C CA  . ARG E 1 229 ? -20.159 35.089  -10.858  1.00 43.98  ? 229 ARG I CA  1 
ATOM   9705  C C   . ARG E 1 229 ? -21.677 35.140  -10.852  1.00 43.49  ? 229 ARG I C   1 
ATOM   9706  O O   . ARG E 1 229 ? -22.303 35.326  -9.806   1.00 42.30  ? 229 ARG I O   1 
ATOM   9707  C CB  . ARG E 1 229 ? -19.701 33.624  -10.782  1.00 38.44  ? 229 ARG I CB  1 
ATOM   9708  C CG  . ARG E 1 229 ? -18.195 33.418  -10.860  1.00 37.54  ? 229 ARG I CG  1 
ATOM   9709  C CD  . ARG E 1 229 ? -17.637 33.799  -12.216  1.00 38.72  ? 229 ARG I CD  1 
ATOM   9710  N NE  . ARG E 1 229 ? -16.209 33.519  -12.301  1.00 49.05  ? 229 ARG I NE  1 
ATOM   9711  C CZ  . ARG E 1 229 ? -15.253 34.398  -12.032  1.00 51.22  ? 229 ARG I CZ  1 
ATOM   9712  N NH1 . ARG E 1 229 ? -15.536 35.642  -11.681  1.00 46.67  ? 229 ARG I NH1 1 
ATOM   9713  N NH2 . ARG E 1 229 ? -13.981 34.018  -12.115  1.00 53.10  ? 229 ARG I NH2 1 
ATOM   9714  N N   . MET E 1 230 ? -22.263 34.967  -12.033  1.00 45.20  ? 230 MET I N   1 
ATOM   9715  C CA  . MET E 1 230 ? -23.705 34.817  -12.167  1.00 50.64  ? 230 MET I CA  1 
ATOM   9716  C C   . MET E 1 230 ? -23.995 33.581  -13.001  1.00 45.11  ? 230 MET I C   1 
ATOM   9717  O O   . MET E 1 230 ? -23.506 33.460  -14.129  1.00 49.64  ? 230 MET I O   1 
ATOM   9718  C CB  . MET E 1 230 ? -24.338 36.062  -12.791  1.00 41.87  ? 230 MET I CB  1 
ATOM   9719  C CG  . MET E 1 230 ? -24.508 37.187  -11.792  1.00 51.42  ? 230 MET I CG  1 
ATOM   9720  S SD  . MET E 1 230 ? -25.049 38.729  -12.534  1.00 54.07  ? 230 MET I SD  1 
ATOM   9721  C CE  . MET E 1 230 ? -24.687 39.858  -11.195  1.00 49.69  ? 230 MET I CE  1 
ATOM   9722  N N   . ASP E 1 231 ? -24.780 32.666  -12.443  1.00 40.06  ? 231 ASP I N   1 
ATOM   9723  C CA  . ASP E 1 231 ? -25.228 31.474  -13.147  1.00 44.37  ? 231 ASP I CA  1 
ATOM   9724  C C   . ASP E 1 231 ? -26.657 31.705  -13.612  1.00 43.71  ? 231 ASP I C   1 
ATOM   9725  O O   . ASP E 1 231 ? -27.539 31.991  -12.795  1.00 42.90  ? 231 ASP I O   1 
ATOM   9726  C CB  . ASP E 1 231 ? -25.147 30.240  -12.248  1.00 51.51  ? 231 ASP I CB  1 
ATOM   9727  C CG  . ASP E 1 231 ? -23.722 29.882  -11.878  1.00 49.76  ? 231 ASP I CG  1 
ATOM   9728  O OD1 . ASP E 1 231 ? -22.805 30.201  -12.663  1.00 51.02  ? 231 ASP I OD1 1 
ATOM   9729  O OD2 . ASP E 1 231 ? -23.520 29.278  -10.804  1.00 58.75  ? 231 ASP I OD2 1 
ATOM   9730  N N   . PHE E 1 232 ? -26.881 31.589  -14.915  1.00 39.68  ? 232 PHE I N   1 
ATOM   9731  C CA  . PHE E 1 232 ? -28.185 31.828  -15.509  1.00 40.45  ? 232 PHE I CA  1 
ATOM   9732  C C   . PHE E 1 232 ? -28.834 30.510  -15.905  1.00 42.28  ? 232 PHE I C   1 
ATOM   9733  O O   . PHE E 1 232 ? -28.154 29.538  -16.248  1.00 45.57  ? 232 PHE I O   1 
ATOM   9734  C CB  . PHE E 1 232 ? -28.077 32.750  -16.727  1.00 43.11  ? 232 PHE I CB  1 
ATOM   9735  C CG  . PHE E 1 232 ? -27.761 34.176  -16.377  1.00 44.11  ? 232 PHE I CG  1 
ATOM   9736  C CD1 . PHE E 1 232 ? -28.763 35.044  -15.981  1.00 51.85  ? 232 PHE I CD1 1 
ATOM   9737  C CD2 . PHE E 1 232 ? -26.460 34.648  -16.443  1.00 47.80  ? 232 PHE I CD2 1 
ATOM   9738  C CE1 . PHE E 1 232 ? -28.475 36.357  -15.657  1.00 62.51  ? 232 PHE I CE1 1 
ATOM   9739  C CE2 . PHE E 1 232 ? -26.166 35.961  -16.121  1.00 43.67  ? 232 PHE I CE2 1 
ATOM   9740  C CZ  . PHE E 1 232 ? -27.174 36.815  -15.727  1.00 46.85  ? 232 PHE I CZ  1 
ATOM   9741  N N   . PHE E 1 233 ? -30.164 30.491  -15.850  1.00 47.68  ? 233 PHE I N   1 
ATOM   9742  C CA  . PHE E 1 233 ? -30.944 29.296  -16.131  1.00 47.39  ? 233 PHE I CA  1 
ATOM   9743  C C   . PHE E 1 233 ? -32.116 29.674  -17.022  1.00 48.70  ? 233 PHE I C   1 
ATOM   9744  O O   . PHE E 1 233 ? -32.525 30.836  -17.082  1.00 53.45  ? 233 PHE I O   1 
ATOM   9745  C CB  . PHE E 1 233 ? -31.433 28.635  -14.835  1.00 42.53  ? 233 PHE I CB  1 
ATOM   9746  C CG  . PHE E 1 233 ? -30.322 28.229  -13.911  1.00 44.60  ? 233 PHE I CG  1 
ATOM   9747  C CD1 . PHE E 1 233 ? -29.758 29.145  -13.036  1.00 36.63  ? 233 PHE I CD1 1 
ATOM   9748  C CD2 . PHE E 1 233 ? -29.833 26.934  -13.925  1.00 37.90  ? 233 PHE I CD2 1 
ATOM   9749  C CE1 . PHE E 1 233 ? -28.727 28.778  -12.193  1.00 39.59  ? 233 PHE I CE1 1 
ATOM   9750  C CE2 . PHE E 1 233 ? -28.805 26.558  -13.082  1.00 50.76  ? 233 PHE I CE2 1 
ATOM   9751  C CZ  . PHE E 1 233 ? -28.252 27.481  -12.213  1.00 46.31  ? 233 PHE I CZ  1 
ATOM   9752  N N   . TRP E 1 234 ? -32.653 28.680  -17.727  1.00 53.13  ? 234 TRP I N   1 
ATOM   9753  C CA  . TRP E 1 234 ? -33.759 28.919  -18.641  1.00 47.18  ? 234 TRP I CA  1 
ATOM   9754  C C   . TRP E 1 234 ? -34.766 27.783  -18.553  1.00 51.01  ? 234 TRP I C   1 
ATOM   9755  O O   . TRP E 1 234 ? -34.458 26.676  -18.105  1.00 49.39  ? 234 TRP I O   1 
ATOM   9756  C CB  . TRP E 1 234 ? -33.278 29.086  -20.088  1.00 41.17  ? 234 TRP I CB  1 
ATOM   9757  C CG  . TRP E 1 234 ? -32.600 27.878  -20.659  1.00 49.83  ? 234 TRP I CG  1 
ATOM   9758  C CD1 . TRP E 1 234 ? -31.289 27.529  -20.513  1.00 43.35  ? 234 TRP I CD1 1 
ATOM   9759  C CD2 . TRP E 1 234 ? -33.194 26.866  -21.483  1.00 45.51  ? 234 TRP I CD2 1 
ATOM   9760  N NE1 . TRP E 1 234 ? -31.031 26.359  -21.188  1.00 42.93  ? 234 TRP I NE1 1 
ATOM   9761  C CE2 . TRP E 1 234 ? -32.184 25.934  -21.793  1.00 48.01  ? 234 TRP I CE2 1 
ATOM   9762  C CE3 . TRP E 1 234 ? -34.482 26.658  -21.987  1.00 51.37  ? 234 TRP I CE3 1 
ATOM   9763  C CZ2 . TRP E 1 234 ? -32.422 24.810  -22.583  1.00 40.25  ? 234 TRP I CZ2 1 
ATOM   9764  C CZ3 . TRP E 1 234 ? -34.716 25.542  -22.773  1.00 48.54  ? 234 TRP I CZ3 1 
ATOM   9765  C CH2 . TRP E 1 234 ? -33.691 24.632  -23.062  1.00 54.05  ? 234 TRP I CH2 1 
ATOM   9766  N N   . THR E 1 235 ? -35.989 28.085  -18.982  1.00 50.41  ? 235 THR I N   1 
ATOM   9767  C CA  . THR E 1 235 ? -37.050 27.096  -19.077  1.00 54.59  ? 235 THR I CA  1 
ATOM   9768  C C   . THR E 1 235 ? -38.013 27.530  -20.170  1.00 52.26  ? 235 THR I C   1 
ATOM   9769  O O   . THR E 1 235 ? -38.018 28.688  -20.597  1.00 48.97  ? 235 THR I O   1 
ATOM   9770  C CB  . THR E 1 235 ? -37.800 26.923  -17.749  1.00 56.39  ? 235 THR I CB  1 
ATOM   9771  O OG1 . THR E 1 235 ? -38.708 25.821  -17.855  1.00 50.89  ? 235 THR I OG1 1 
ATOM   9772  C CG2 . THR E 1 235 ? -38.588 28.182  -17.411  1.00 50.27  ? 235 THR I CG2 1 
ATOM   9773  N N   . ILE E 1 236 ? -38.820 26.582  -20.630  1.00 49.41  ? 236 ILE I N   1 
ATOM   9774  C CA  . ILE E 1 236 ? -39.900 26.853  -21.570  1.00 49.81  ? 236 ILE I CA  1 
ATOM   9775  C C   . ILE E 1 236 ? -41.201 26.752  -20.789  1.00 52.81  ? 236 ILE I C   1 
ATOM   9776  O O   . ILE E 1 236 ? -41.566 25.669  -20.314  1.00 56.23  ? 236 ILE I O   1 
ATOM   9777  C CB  . ILE E 1 236 ? -39.891 25.886  -22.760  1.00 49.18  ? 236 ILE I CB  1 
ATOM   9778  C CG1 . ILE E 1 236 ? -38.604 26.036  -23.573  1.00 47.74  ? 236 ILE I CG1 1 
ATOM   9779  C CG2 . ILE E 1 236 ? -41.112 26.122  -23.635  1.00 51.26  ? 236 ILE I CG2 1 
ATOM   9780  C CD1 . ILE E 1 236 ? -38.452 27.384  -24.241  1.00 49.35  ? 236 ILE I CD1 1 
ATOM   9781  N N   . LEU E 1 237 ? -41.898 27.875  -20.645  1.00 57.52  ? 237 LEU I N   1 
ATOM   9782  C CA  . LEU E 1 237 ? -43.177 27.913  -19.946  1.00 59.32  ? 237 LEU I CA  1 
ATOM   9783  C C   . LEU E 1 237 ? -44.290 27.722  -20.971  1.00 55.42  ? 237 LEU I C   1 
ATOM   9784  O O   . LEU E 1 237 ? -44.540 28.604  -21.797  1.00 58.03  ? 237 LEU I O   1 
ATOM   9785  C CB  . LEU E 1 237 ? -43.337 29.226  -19.184  1.00 53.56  ? 237 LEU I CB  1 
ATOM   9786  C CG  . LEU E 1 237 ? -44.469 29.300  -18.158  1.00 57.43  ? 237 LEU I CG  1 
ATOM   9787  C CD1 . LEU E 1 237 ? -44.271 28.268  -17.054  1.00 56.75  ? 237 LEU I CD1 1 
ATOM   9788  C CD2 . LEU E 1 237 ? -44.575 30.702  -17.573  1.00 50.75  ? 237 LEU I CD2 1 
ATOM   9789  N N   . LYS E 1 238 ? -44.949 26.566  -20.923  1.00 63.46  ? 238 LYS I N   1 
ATOM   9790  C CA  . LYS E 1 238 ? -46.009 26.264  -21.872  1.00 65.17  ? 238 LYS I CA  1 
ATOM   9791  C C   . LYS E 1 238 ? -47.238 27.124  -21.583  1.00 60.04  ? 238 LYS I C   1 
ATOM   9792  O O   . LYS E 1 238 ? -47.412 27.617  -20.464  1.00 61.30  ? 238 LYS I O   1 
ATOM   9793  C CB  . LYS E 1 238 ? -46.357 24.778  -21.812  1.00 63.76  ? 238 LYS I CB  1 
ATOM   9794  C CG  . LYS E 1 238 ? -45.224 23.882  -22.290  1.00 73.34  ? 238 LYS I CG  1 
ATOM   9795  C CD  . LYS E 1 238 ? -45.602 22.408  -22.308  1.00 83.22  ? 238 LYS I CD  1 
ATOM   9796  C CE  . LYS E 1 238 ? -46.027 21.964  -23.700  1.00 102.60 ? 238 LYS I CE  1 
ATOM   9797  N NZ  . LYS E 1 238 ? -45.124 22.509  -24.756  1.00 90.79  ? 238 LYS I NZ  1 
ATOM   9798  N N   . PRO E 1 239 ? -48.096 27.336  -22.583  1.00 63.87  ? 239 PRO I N   1 
ATOM   9799  C CA  . PRO E 1 239 ? -49.273 28.187  -22.371  1.00 71.17  ? 239 PRO I CA  1 
ATOM   9800  C C   . PRO E 1 239 ? -50.153 27.665  -21.247  1.00 61.08  ? 239 PRO I C   1 
ATOM   9801  O O   . PRO E 1 239 ? -50.288 26.456  -21.050  1.00 70.12  ? 239 PRO I O   1 
ATOM   9802  C CB  . PRO E 1 239 ? -49.995 28.138  -23.722  1.00 67.61  ? 239 PRO I CB  1 
ATOM   9803  C CG  . PRO E 1 239 ? -48.929 27.814  -24.704  1.00 65.32  ? 239 PRO I CG  1 
ATOM   9804  C CD  . PRO E 1 239 ? -47.984 26.898  -23.985  1.00 57.16  ? 239 PRO I CD  1 
ATOM   9805  N N   . ASN E 1 240 ? -50.733 28.603  -20.498  1.00 51.85  ? 240 ASN I N   1 
ATOM   9806  C CA  . ASN E 1 240 ? -51.602 28.384  -19.345  1.00 71.18  ? 240 ASN I CA  1 
ATOM   9807  C C   . ASN E 1 240 ? -50.859 27.806  -18.147  1.00 69.47  ? 240 ASN I C   1 
ATOM   9808  O O   . ASN E 1 240 ? -51.499 27.474  -17.142  1.00 58.65  ? 240 ASN I O   1 
ATOM   9809  C CB  . ASN E 1 240 ? -52.805 27.490  -19.674  1.00 70.19  ? 240 ASN I CB  1 
ATOM   9810  C CG  . ASN E 1 240 ? -53.712 28.102  -20.717  1.00 78.32  ? 240 ASN I CG  1 
ATOM   9811  O OD1 . ASN E 1 240 ? -54.097 29.268  -20.616  1.00 90.45  ? 240 ASN I OD1 1 
ATOM   9812  N ND2 . ASN E 1 240 ? -54.046 27.322  -21.740  1.00 84.95  ? 240 ASN I ND2 1 
ATOM   9813  N N   . ASP E 1 241 ? -49.539 27.662  -18.219  1.00 63.49  ? 241 ASP I N   1 
ATOM   9814  C CA  . ASP E 1 241 ? -48.719 27.309  -17.070  1.00 55.97  ? 241 ASP I CA  1 
ATOM   9815  C C   . ASP E 1 241 ? -48.139 28.577  -16.457  1.00 52.59  ? 241 ASP I C   1 
ATOM   9816  O O   . ASP E 1 241 ? -48.031 29.618  -17.110  1.00 54.10  ? 241 ASP I O   1 
ATOM   9817  C CB  . ASP E 1 241 ? -47.591 26.350  -17.473  1.00 59.28  ? 241 ASP I CB  1 
ATOM   9818  C CG  . ASP E 1 241 ? -46.898 25.724  -16.272  1.00 73.07  ? 241 ASP I CG  1 
ATOM   9819  O OD1 . ASP E 1 241 ? -47.413 25.868  -15.141  1.00 59.92  ? 241 ASP I OD1 1 
ATOM   9820  O OD2 . ASP E 1 241 ? -45.835 25.091  -16.459  1.00 58.00  ? 241 ASP I OD2 1 
ATOM   9821  N N   . ALA E 1 242 ? -47.770 28.482  -15.184  1.00 56.23  ? 242 ALA I N   1 
ATOM   9822  C CA  . ALA E 1 242 ? -47.211 29.611  -14.460  1.00 65.05  ? 242 ALA I CA  1 
ATOM   9823  C C   . ALA E 1 242 ? -45.861 29.238  -13.862  1.00 55.86  ? 242 ALA I C   1 
ATOM   9824  O O   . ALA E 1 242 ? -45.598 28.073  -13.550  1.00 56.38  ? 242 ALA I O   1 
ATOM   9825  C CB  . ALA E 1 242 ? -48.153 30.093  -13.347  1.00 58.35  ? 242 ALA I CB  1 
ATOM   9826  N N   . ILE E 1 243 ? -45.005 30.243  -13.714  1.00 54.80  ? 243 ILE I N   1 
ATOM   9827  C CA  . ILE E 1 243 ? -43.695 30.091  -13.097  1.00 55.36  ? 243 ILE I CA  1 
ATOM   9828  C C   . ILE E 1 243 ? -43.701 30.883  -11.797  1.00 59.77  ? 243 ILE I C   1 
ATOM   9829  O O   . ILE E 1 243 ? -44.192 32.018  -11.755  1.00 61.31  ? 243 ILE I O   1 
ATOM   9830  C CB  . ILE E 1 243 ? -42.569 30.549  -14.043  1.00 63.31  ? 243 ILE I CB  1 
ATOM   9831  C CG1 . ILE E 1 243 ? -41.200 30.403  -13.373  1.00 56.86  ? 243 ILE I CG1 1 
ATOM   9832  C CG2 . ILE E 1 243 ? -42.802 31.977  -14.526  1.00 50.60  ? 243 ILE I CG2 1 
ATOM   9833  C CD1 . ILE E 1 243 ? -40.048 30.450  -14.354  1.00 42.08  ? 243 ILE I CD1 1 
ATOM   9834  N N   . HIS E 1 244 ? -43.192 30.274  -10.730  1.00 49.31  ? 244 HIS I N   1 
ATOM   9835  C CA  . HIS E 1 244 ? -43.237 30.863  -9.399   1.00 53.93  ? 244 HIS I CA  1 
ATOM   9836  C C   . HIS E 1 244 ? -41.815 31.089  -8.908   1.00 53.86  ? 244 HIS I C   1 
ATOM   9837  O O   . HIS E 1 244 ? -41.049 30.131  -8.761   1.00 58.05  ? 244 HIS I O   1 
ATOM   9838  C CB  . HIS E 1 244 ? -44.011 29.962  -8.436   1.00 39.83  ? 244 HIS I CB  1 
ATOM   9839  C CG  . HIS E 1 244 ? -45.333 29.507  -8.973   1.00 71.04  ? 244 HIS I CG  1 
ATOM   9840  N ND1 . HIS E 1 244 ? -46.532 30.039  -8.550   1.00 63.31  ? 244 HIS I ND1 1 
ATOM   9841  C CD2 . HIS E 1 244 ? -45.644 28.578  -9.908   1.00 57.27  ? 244 HIS I CD2 1 
ATOM   9842  C CE1 . HIS E 1 244 ? -47.524 29.453  -9.196   1.00 62.85  ? 244 HIS I CE1 1 
ATOM   9843  N NE2 . HIS E 1 244 ? -47.012 28.563  -10.027  1.00 68.31  ? 244 HIS I NE2 1 
ATOM   9844  N N   . PHE E 1 245 ? -41.472 32.348  -8.653   1.00 51.77  ? 245 PHE I N   1 
ATOM   9845  C CA  . PHE E 1 245 ? -40.165 32.726  -8.135   1.00 52.47  ? 245 PHE I CA  1 
ATOM   9846  C C   . PHE E 1 245 ? -40.260 33.030  -6.646   1.00 53.08  ? 245 PHE I C   1 
ATOM   9847  O O   . PHE E 1 245 ? -41.253 33.596  -6.178   1.00 55.38  ? 245 PHE I O   1 
ATOM   9848  C CB  . PHE E 1 245 ? -39.610 33.950  -8.867   1.00 49.12  ? 245 PHE I CB  1 
ATOM   9849  C CG  . PHE E 1 245 ? -39.271 33.702  -10.308  1.00 52.98  ? 245 PHE I CG  1 
ATOM   9850  C CD1 . PHE E 1 245 ? -38.112 33.025  -10.654  1.00 47.53  ? 245 PHE I CD1 1 
ATOM   9851  C CD2 . PHE E 1 245 ? -40.096 34.169  -11.318  1.00 51.86  ? 245 PHE I CD2 1 
ATOM   9852  C CE1 . PHE E 1 245 ? -37.791 32.806  -11.980  1.00 59.22  ? 245 PHE I CE1 1 
ATOM   9853  C CE2 . PHE E 1 245 ? -39.780 33.954  -12.647  1.00 57.17  ? 245 PHE I CE2 1 
ATOM   9854  C CZ  . PHE E 1 245 ? -38.625 33.272  -12.979  1.00 52.21  ? 245 PHE I CZ  1 
ATOM   9855  N N   . GLU E 1 246 ? -39.219 32.657  -5.907   1.00 52.52  ? 246 GLU I N   1 
ATOM   9856  C CA  . GLU E 1 246 ? -39.141 32.971  -4.484   1.00 51.50  ? 246 GLU I CA  1 
ATOM   9857  C C   . GLU E 1 246 ? -37.678 33.051  -4.084   1.00 49.92  ? 246 GLU I C   1 
ATOM   9858  O O   . GLU E 1 246 ? -36.925 32.098  -4.305   1.00 51.69  ? 246 GLU I O   1 
ATOM   9859  C CB  . GLU E 1 246 ? -39.880 31.924  -3.645   1.00 57.72  ? 246 GLU I CB  1 
ATOM   9860  C CG  . GLU E 1 246 ? -39.806 32.165  -2.143   1.00 53.10  ? 246 GLU I CG  1 
ATOM   9861  C CD  . GLU E 1 246 ? -40.700 31.226  -1.359   1.00 66.78  ? 246 GLU I CD  1 
ATOM   9862  O OE1 . GLU E 1 246 ? -41.786 30.876  -1.867   1.00 76.12  ? 246 GLU I OE1 1 
ATOM   9863  O OE2 . GLU E 1 246 ? -40.314 30.834  -0.237   1.00 76.36  ? 246 GLU I OE2 1 
ATOM   9864  N N   . SER E 1 247 ? -37.277 34.179  -3.501   1.00 51.00  ? 247 SER I N   1 
ATOM   9865  C CA  . SER E 1 247 ? -35.886 34.370  -3.115   1.00 47.22  ? 247 SER I CA  1 
ATOM   9866  C C   . SER E 1 247 ? -35.787 35.439  -2.039   1.00 52.96  ? 247 SER I C   1 
ATOM   9867  O O   . SER E 1 247 ? -36.613 36.352  -1.971   1.00 54.74  ? 247 SER I O   1 
ATOM   9868  C CB  . SER E 1 247 ? -35.019 34.763  -4.315   1.00 52.87  ? 247 SER I CB  1 
ATOM   9869  O OG  . SER E 1 247 ? -33.745 35.213  -3.884   1.00 51.86  ? 247 SER I OG  1 
ATOM   9870  N N   . ASN E 1 248 ? -34.752 35.315  -1.205   1.00 47.60  ? 248 ASN I N   1 
ATOM   9871  C CA  . ASN E 1 248 ? -34.415 36.330  -0.214   1.00 49.28  ? 248 ASN I CA  1 
ATOM   9872  C C   . ASN E 1 248 ? -33.024 36.907  -0.450   1.00 54.61  ? 248 ASN I C   1 
ATOM   9873  O O   . ASN E 1 248 ? -32.406 37.431  0.482    1.00 50.74  ? 248 ASN I O   1 
ATOM   9874  C CB  . ASN E 1 248 ? -34.528 35.764  1.205    1.00 48.16  ? 248 ASN I CB  1 
ATOM   9875  C CG  . ASN E 1 248 ? -33.566 34.617  1.457    1.00 62.39  ? 248 ASN I CG  1 
ATOM   9876  O OD1 . ASN E 1 248 ? -33.148 33.929  0.527    1.00 53.89  ? 248 ASN I OD1 1 
ATOM   9877  N ND2 . ASN E 1 248 ? -33.214 34.404  2.721    1.00 46.82  ? 248 ASN I ND2 1 
ATOM   9878  N N   . GLY E 1 249 ? -32.521 36.823  -1.672   1.00 46.39  ? 249 GLY I N   1 
ATOM   9879  C CA  . GLY E 1 249 ? -31.230 37.391  -1.998   1.00 52.18  ? 249 GLY I CA  1 
ATOM   9880  C C   . GLY E 1 249 ? -30.616 36.727  -3.206   1.00 53.72  ? 249 GLY I C   1 
ATOM   9881  O O   . GLY E 1 249 ? -30.961 35.604  -3.581   1.00 52.11  ? 249 GLY I O   1 
ATOM   9882  N N   . ASN E 1 250 ? -29.694 37.460  -3.835   1.00 51.91  ? 250 ASN I N   1 
ATOM   9883  C CA  . ASN E 1 250 ? -28.850 36.982  -4.928   1.00 49.52  ? 250 ASN I CA  1 
ATOM   9884  C C   . ASN E 1 250 ? -29.632 36.666  -6.198   1.00 43.34  ? 250 ASN I C   1 
ATOM   9885  O O   . ASN E 1 250 ? -29.136 35.943  -7.066   1.00 50.85  ? 250 ASN I O   1 
ATOM   9886  C CB  . ASN E 1 250 ? -28.038 35.753  -4.498   1.00 41.10  ? 250 ASN I CB  1 
ATOM   9887  C CG  . ASN E 1 250 ? -27.135 36.037  -3.313   1.00 50.93  ? 250 ASN I CG  1 
ATOM   9888  O OD1 . ASN E 1 250 ? -27.596 36.145  -2.173   1.00 42.25  ? 250 ASN I OD1 1 
ATOM   9889  N ND2 . ASN E 1 250 ? -25.838 36.151  -3.575   1.00 44.33  ? 250 ASN I ND2 1 
ATOM   9890  N N   . PHE E 1 251 ? -30.838 37.207  -6.343   1.00 59.40  ? 251 PHE I N   1 
ATOM   9891  C CA  . PHE E 1 251 ? -31.728 36.841  -7.437   1.00 43.83  ? 251 PHE I CA  1 
ATOM   9892  C C   . PHE E 1 251 ? -31.581 37.816  -8.599   1.00 45.88  ? 251 PHE I C   1 
ATOM   9893  O O   . PHE E 1 251 ? -31.693 39.032  -8.418   1.00 54.72  ? 251 PHE I O   1 
ATOM   9894  C CB  . PHE E 1 251 ? -33.174 36.811  -6.937   1.00 47.57  ? 251 PHE I CB  1 
ATOM   9895  C CG  . PHE E 1 251 ? -34.175 36.396  -7.975   1.00 56.25  ? 251 PHE I CG  1 
ATOM   9896  C CD1 . PHE E 1 251 ? -33.908 35.346  -8.840   1.00 43.14  ? 251 PHE I CD1 1 
ATOM   9897  C CD2 . PHE E 1 251 ? -35.400 37.038  -8.065   1.00 45.92  ? 251 PHE I CD2 1 
ATOM   9898  C CE1 . PHE E 1 251 ? -34.838 34.961  -9.789   1.00 47.68  ? 251 PHE I CE1 1 
ATOM   9899  C CE2 . PHE E 1 251 ? -36.333 36.654  -9.006   1.00 46.59  ? 251 PHE I CE2 1 
ATOM   9900  C CZ  . PHE E 1 251 ? -36.051 35.617  -9.872   1.00 49.91  ? 251 PHE I CZ  1 
ATOM   9901  N N   . ILE E 1 252 ? -31.328 37.278  -9.789   1.00 51.76  ? 252 ILE I N   1 
ATOM   9902  C CA  . ILE E 1 252 ? -31.268 38.070  -11.017  1.00 47.98  ? 252 ILE I CA  1 
ATOM   9903  C C   . ILE E 1 252 ? -32.585 37.809  -11.742  1.00 49.02  ? 252 ILE I C   1 
ATOM   9904  O O   . ILE E 1 252 ? -32.720 36.861  -12.516  1.00 53.13  ? 252 ILE I O   1 
ATOM   9905  C CB  . ILE E 1 252 ? -30.054 37.717  -11.874  1.00 49.87  ? 252 ILE I CB  1 
ATOM   9906  C CG1 . ILE E 1 252 ? -28.779 37.707  -11.028  1.00 50.80  ? 252 ILE I CG1 1 
ATOM   9907  C CG2 . ILE E 1 252 ? -29.914 38.707  -13.026  1.00 43.14  ? 252 ILE I CG2 1 
ATOM   9908  C CD1 . ILE E 1 252 ? -28.342 39.073  -10.563  1.00 45.60  ? 252 ILE I CD1 1 
ATOM   9909  N N   . ALA E 1 253 ? -33.565 38.669  -11.489  1.00 52.41  ? 253 ALA I N   1 
ATOM   9910  C CA  . ALA E 1 253 ? -34.925 38.436  -11.941  1.00 48.82  ? 253 ALA I CA  1 
ATOM   9911  C C   . ALA E 1 253 ? -35.067 38.687  -13.440  1.00 47.65  ? 253 ALA I C   1 
ATOM   9912  O O   . ALA E 1 253 ? -34.382 39.543  -14.004  1.00 58.76  ? 253 ALA I O   1 
ATOM   9913  C CB  . ALA E 1 253 ? -35.895 39.334  -11.183  1.00 52.77  ? 253 ALA I CB  1 
ATOM   9914  N N   . PRO E 1 254 ? -35.946 37.944  -14.106  1.00 44.83  ? 254 PRO I N   1 
ATOM   9915  C CA  . PRO E 1 254 ? -36.274 38.272  -15.494  1.00 52.19  ? 254 PRO I CA  1 
ATOM   9916  C C   . PRO E 1 254 ? -37.130 39.524  -15.576  1.00 63.77  ? 254 PRO I C   1 
ATOM   9917  O O   . PRO E 1 254 ? -37.915 39.834  -14.676  1.00 62.49  ? 254 PRO I O   1 
ATOM   9918  C CB  . PRO E 1 254 ? -37.050 37.042  -15.975  1.00 46.41  ? 254 PRO I CB  1 
ATOM   9919  C CG  . PRO E 1 254 ? -37.664 36.489  -14.735  1.00 45.12  ? 254 PRO I CG  1 
ATOM   9920  C CD  . PRO E 1 254 ? -36.685 36.763  -13.624  1.00 37.10  ? 254 PRO I CD  1 
ATOM   9921  N N   . GLU E 1 255 ? -36.959 40.253  -16.674  1.00 56.42  ? 255 GLU I N   1 
ATOM   9922  C CA  . GLU E 1 255 ? -37.871 41.326  -17.046  1.00 59.73  ? 255 GLU I CA  1 
ATOM   9923  C C   . GLU E 1 255 ? -38.556 41.048  -18.372  1.00 58.25  ? 255 GLU I C   1 
ATOM   9924  O O   . GLU E 1 255 ? -39.784 41.158  -18.467  1.00 63.24  ? 255 GLU I O   1 
ATOM   9925  C CB  . GLU E 1 255 ? -37.133 42.673  -17.123  1.00 60.79  ? 255 GLU I CB  1 
ATOM   9926  C CG  . GLU E 1 255 ? -37.840 43.690  -18.023  1.00 81.21  ? 255 GLU I CG  1 
ATOM   9927  C CD  . GLU E 1 255 ? -37.424 45.123  -17.766  1.00 92.69  ? 255 GLU I CD  1 
ATOM   9928  O OE1 . GLU E 1 255 ? -36.631 45.665  -18.564  1.00 91.40  ? 255 GLU I OE1 1 
ATOM   9929  O OE2 . GLU E 1 255 ? -37.896 45.702  -16.763  1.00 83.98  ? 255 GLU I OE2 1 
ATOM   9930  N N   . TYR E 1 256 ? -37.792 40.686  -19.396  1.00 65.71  ? 256 TYR I N   1 
ATOM   9931  C CA  . TYR E 1 256 ? -38.332 40.280  -20.683  1.00 65.82  ? 256 TYR I CA  1 
ATOM   9932  C C   . TYR E 1 256 ? -38.304 38.762  -20.809  1.00 68.41  ? 256 TYR I C   1 
ATOM   9933  O O   . TYR E 1 256 ? -37.499 38.079  -20.171  1.00 69.75  ? 256 TYR I O   1 
ATOM   9934  C CB  . TYR E 1 256 ? -37.543 40.903  -21.838  1.00 62.75  ? 256 TYR I CB  1 
ATOM   9935  C CG  . TYR E 1 256 ? -37.694 42.405  -21.965  1.00 76.81  ? 256 TYR I CG  1 
ATOM   9936  C CD1 . TYR E 1 256 ? -38.650 42.970  -22.817  1.00 71.86  ? 256 TYR I CD1 1 
ATOM   9937  C CD2 . TYR E 1 256 ? -36.864 43.259  -21.253  1.00 75.76  ? 256 TYR I CD2 1 
ATOM   9938  C CE1 . TYR E 1 256 ? -38.775 44.349  -22.931  1.00 70.47  ? 256 TYR I CE1 1 
ATOM   9939  C CE2 . TYR E 1 256 ? -36.980 44.626  -21.360  1.00 78.65  ? 256 TYR I CE2 1 
ATOM   9940  C CZ  . TYR E 1 256 ? -37.932 45.170  -22.190  1.00 82.35  ? 256 TYR I CZ  1 
ATOM   9941  O OH  . TYR E 1 256 ? -37.997 46.543  -22.251  1.00 100.57 ? 256 TYR I OH  1 
ATOM   9942  N N   . ALA E 1 257 ? -39.208 38.242  -21.633  1.00 64.00  ? 257 ALA I N   1 
ATOM   9943  C CA  . ALA E 1 257 ? -39.223 36.844  -22.031  1.00 56.18  ? 257 ALA I CA  1 
ATOM   9944  C C   . ALA E 1 257 ? -39.438 36.791  -23.538  1.00 54.87  ? 257 ALA I C   1 
ATOM   9945  O O   . ALA E 1 257 ? -39.616 37.821  -24.194  1.00 63.98  ? 257 ALA I O   1 
ATOM   9946  C CB  . ALA E 1 257 ? -40.302 36.056  -21.279  1.00 50.90  ? 257 ALA I CB  1 
ATOM   9947  N N   . TYR E 1 258 ? -39.419 35.585  -24.100  1.00 53.65  ? 258 TYR I N   1 
ATOM   9948  C CA  . TYR E 1 258 ? -39.490 35.414  -25.546  1.00 56.26  ? 258 TYR I CA  1 
ATOM   9949  C C   . TYR E 1 258 ? -40.581 34.417  -25.902  1.00 65.27  ? 258 TYR I C   1 
ATOM   9950  O O   . TYR E 1 258 ? -40.491 33.239  -25.541  1.00 63.64  ? 258 TYR I O   1 
ATOM   9951  C CB  . TYR E 1 258 ? -38.147 34.947  -26.111  1.00 57.40  ? 258 TYR I CB  1 
ATOM   9952  C CG  . TYR E 1 258 ? -37.018 35.932  -25.920  1.00 61.45  ? 258 TYR I CG  1 
ATOM   9953  C CD1 . TYR E 1 258 ? -36.935 37.079  -26.697  1.00 56.70  ? 258 TYR I CD1 1 
ATOM   9954  C CD2 . TYR E 1 258 ? -36.029 35.709  -24.972  1.00 52.92  ? 258 TYR I CD2 1 
ATOM   9955  C CE1 . TYR E 1 258 ? -35.899 37.978  -26.535  1.00 67.93  ? 258 TYR I CE1 1 
ATOM   9956  C CE2 . TYR E 1 258 ? -34.990 36.604  -24.801  1.00 64.32  ? 258 TYR I CE2 1 
ATOM   9957  C CZ  . TYR E 1 258 ? -34.930 37.737  -25.585  1.00 74.21  ? 258 TYR I CZ  1 
ATOM   9958  O OH  . TYR E 1 258 ? -33.898 38.632  -25.419  1.00 73.04  ? 258 TYR I OH  1 
ATOM   9959  N N   . LYS E 1 259 ? -41.602 34.887  -26.616  1.00 52.40  ? 259 LYS I N   1 
ATOM   9960  C CA  . LYS E 1 259 ? -42.567 33.980  -27.220  1.00 59.77  ? 259 LYS I CA  1 
ATOM   9961  C C   . LYS E 1 259 ? -41.908 33.265  -28.391  1.00 63.94  ? 259 LYS I C   1 
ATOM   9962  O O   . LYS E 1 259 ? -41.363 33.906  -29.295  1.00 66.72  ? 259 LYS I O   1 
ATOM   9963  C CB  . LYS E 1 259 ? -43.801 34.749  -27.686  1.00 68.27  ? 259 LYS I CB  1 
ATOM   9964  C CG  . LYS E 1 259 ? -44.499 35.524  -26.582  1.00 83.19  ? 259 LYS I CG  1 
ATOM   9965  C CD  . LYS E 1 259 ? -45.377 36.619  -27.159  1.00 78.74  ? 259 LYS I CD  1 
ATOM   9966  C CE  . LYS E 1 259 ? -46.493 36.050  -28.013  1.00 80.85  ? 259 LYS I CE  1 
ATOM   9967  N NZ  . LYS E 1 259 ? -47.061 37.089  -28.917  1.00 81.51  ? 259 LYS I NZ  1 
ATOM   9968  N N   . ILE E 1 260 ? -41.947 31.936  -28.375  1.00 58.61  ? 260 ILE I N   1 
ATOM   9969  C CA  . ILE E 1 260 ? -41.165 31.135  -29.309  1.00 56.46  ? 260 ILE I CA  1 
ATOM   9970  C C   . ILE E 1 260 ? -42.036 30.025  -29.876  1.00 61.48  ? 260 ILE I C   1 
ATOM   9971  O O   . ILE E 1 260 ? -42.701 29.302  -29.127  1.00 68.40  ? 260 ILE I O   1 
ATOM   9972  C CB  . ILE E 1 260 ? -39.904 30.557  -28.634  1.00 61.75  ? 260 ILE I CB  1 
ATOM   9973  C CG1 . ILE E 1 260 ? -39.290 29.444  -29.484  1.00 67.56  ? 260 ILE I CG1 1 
ATOM   9974  C CG2 . ILE E 1 260 ? -40.222 30.067  -27.226  1.00 62.47  ? 260 ILE I CG2 1 
ATOM   9975  C CD1 . ILE E 1 260 ? -38.006 28.889  -28.911  1.00 77.71  ? 260 ILE I CD1 1 
ATOM   9976  N N   . VAL E 1 261 A -42.039 29.900  -31.201  1.00 69.00  ? 260 VAL I N   1 
ATOM   9977  C CA  . VAL E 1 261 A -42.658 28.784  -31.904  1.00 61.28  ? 260 VAL I CA  1 
ATOM   9978  C C   . VAL E 1 261 A -41.578 28.105  -32.732  1.00 71.19  ? 260 VAL I C   1 
ATOM   9979  O O   . VAL E 1 261 A -40.872 28.768  -33.500  1.00 65.26  ? 260 VAL I O   1 
ATOM   9980  C CB  . VAL E 1 261 A -43.823 29.242  -32.801  1.00 69.00  ? 260 VAL I CB  1 
ATOM   9981  C CG1 . VAL E 1 261 A -44.468 28.047  -33.483  1.00 60.03  ? 260 VAL I CG1 1 
ATOM   9982  C CG2 . VAL E 1 261 A -44.843 30.012  -31.991  1.00 63.90  ? 260 VAL I CG2 1 
ATOM   9983  N N   . LYS E 1 262 ? -41.448 26.791  -32.572  1.00 64.37  ? 261 LYS I N   1 
ATOM   9984  C CA  . LYS E 1 262 ? -40.436 26.012  -33.269  1.00 55.10  ? 261 LYS I CA  1 
ATOM   9985  C C   . LYS E 1 262 ? -41.117 24.949  -34.117  1.00 56.90  ? 261 LYS I C   1 
ATOM   9986  O O   . LYS E 1 262 ? -41.991 24.225  -33.629  1.00 55.58  ? 261 LYS I O   1 
ATOM   9987  C CB  . LYS E 1 262 ? -39.462 25.365  -32.279  1.00 63.48  ? 261 LYS I CB  1 
ATOM   9988  C CG  . LYS E 1 262 ? -38.307 24.624  -32.931  1.00 61.01  ? 261 LYS I CG  1 
ATOM   9989  C CD  . LYS E 1 262 ? -37.380 24.022  -31.888  1.00 66.92  ? 261 LYS I CD  1 
ATOM   9990  C CE  . LYS E 1 262 ? -36.225 23.277  -32.537  1.00 59.89  ? 261 LYS I CE  1 
ATOM   9991  N NZ  . LYS E 1 262 ? -35.396 24.172  -33.395  1.00 61.40  ? 261 LYS I NZ  1 
ATOM   9992  N N   . LYS E 1 263 ? -40.715 24.860  -35.384  1.00 69.34  ? 262 LYS I N   1 
ATOM   9993  C CA  . LYS E 1 263 ? -41.252 23.883  -36.322  1.00 72.16  ? 262 LYS I CA  1 
ATOM   9994  C C   . LYS E 1 263 ? -40.210 22.875  -36.783  1.00 77.84  ? 262 LYS I C   1 
ATOM   9995  O O   . LYS E 1 263 ? -40.477 21.670  -36.793  1.00 90.24  ? 262 LYS I O   1 
ATOM   9996  C CB  . LYS E 1 263 ? -41.849 24.598  -37.542  1.00 69.98  ? 262 LYS I CB  1 
ATOM   9997  C CG  . LYS E 1 263 ? -43.034 25.486  -37.222  1.00 68.16  ? 262 LYS I CG  1 
ATOM   9998  C CD  . LYS E 1 263 ? -44.255 24.664  -36.847  1.00 79.03  ? 262 LYS I CD  1 
ATOM   9999  C CE  . LYS E 1 263 ? -45.470 25.561  -36.692  1.00 78.96  ? 262 LYS I CE  1 
ATOM   10000 N NZ  . LYS E 1 263 ? -45.532 26.551  -37.805  1.00 74.27  ? 262 LYS I NZ  1 
ATOM   10001 N N   . GLY E 1 264 ? -39.021 23.342  -37.167  1.00 71.07  ? 263 GLY I N   1 
ATOM   10002 C CA  . GLY E 1 264 ? -37.985 22.475  -37.687  1.00 69.05  ? 263 GLY I CA  1 
ATOM   10003 C C   . GLY E 1 264 ? -36.682 22.642  -36.925  1.00 69.43  ? 263 GLY I C   1 
ATOM   10004 O O   . GLY E 1 264 ? -36.604 23.376  -35.937  1.00 70.36  ? 263 GLY I O   1 
ATOM   10005 N N   . ASP E 1 265 ? -35.661 21.947  -37.418  1.00 69.37  ? 264 ASP I N   1 
ATOM   10006 C CA  . ASP E 1 265 ? -34.361 21.893  -36.768  1.00 69.00  ? 264 ASP I CA  1 
ATOM   10007 C C   . ASP E 1 265 ? -33.265 22.380  -37.707  1.00 61.86  ? 264 ASP I C   1 
ATOM   10008 O O   . ASP E 1 265 ? -33.363 22.258  -38.932  1.00 56.38  ? 264 ASP I O   1 
ATOM   10009 C CB  . ASP E 1 265 ? -34.039 20.472  -36.291  1.00 60.31  ? 264 ASP I CB  1 
ATOM   10010 C CG  . ASP E 1 265 ? -34.580 20.188  -34.906  1.00 79.02  ? 264 ASP I CG  1 
ATOM   10011 O OD1 . ASP E 1 265 ? -34.301 20.985  -33.985  1.00 89.84  ? 264 ASP I OD1 1 
ATOM   10012 O OD2 . ASP E 1 265 ? -35.291 19.174  -34.741  1.00 81.75  ? 264 ASP I OD2 1 
ATOM   10013 N N   . SER E 1 266 ? -32.217 22.928  -37.107  1.00 58.28  ? 265 SER I N   1 
ATOM   10014 C CA  . SER E 1 266 ? -31.058 23.442  -37.823  1.00 56.72  ? 265 SER I CA  1 
ATOM   10015 C C   . SER E 1 266 ? -29.845 23.259  -36.918  1.00 52.51  ? 265 SER I C   1 
ATOM   10016 O O   . SER E 1 266 ? -29.871 22.451  -35.983  1.00 58.02  ? 265 SER I O   1 
ATOM   10017 C CB  . SER E 1 266 ? -31.290 24.906  -38.236  1.00 54.82  ? 265 SER I CB  1 
ATOM   10018 O OG  . SER E 1 266 ? -30.192 25.414  -38.969  1.00 63.95  ? 265 SER I OG  1 
ATOM   10019 N N   . THR E 1 267 ? -28.769 23.985  -37.207  1.00 50.43  ? 266 THR I N   1 
ATOM   10020 C CA  . THR E 1 267 ? -27.622 24.042  -36.316  1.00 54.80  ? 266 THR I CA  1 
ATOM   10021 C C   . THR E 1 267 ? -27.039 25.446  -36.372  1.00 59.27  ? 266 THR I C   1 
ATOM   10022 O O   . THR E 1 267 ? -27.541 26.322  -37.084  1.00 56.61  ? 266 THR I O   1 
ATOM   10023 C CB  . THR E 1 267 ? -26.568 22.988  -36.676  1.00 60.28  ? 266 THR I CB  1 
ATOM   10024 O OG1 . THR E 1 267 ? -25.575 22.935  -35.643  1.00 61.82  ? 266 THR I OG1 1 
ATOM   10025 C CG2 . THR E 1 267 ? -25.893 23.335  -37.990  1.00 57.25  ? 266 THR I CG2 1 
ATOM   10026 N N   . ILE E 1 268 ? -25.977 25.663  -35.605  1.00 50.29  ? 267 ILE I N   1 
ATOM   10027 C CA  . ILE E 1 268 ? -25.279 26.941  -35.563  1.00 50.95  ? 267 ILE I CA  1 
ATOM   10028 C C   . ILE E 1 268 ? -24.087 26.871  -36.506  1.00 56.16  ? 267 ILE I C   1 
ATOM   10029 O O   . ILE E 1 268 ? -23.326 25.896  -36.487  1.00 55.99  ? 267 ILE I O   1 
ATOM   10030 C CB  . ILE E 1 268 ? -24.838 27.290  -34.131  1.00 68.40  ? 267 ILE I CB  1 
ATOM   10031 C CG1 . ILE E 1 268 ? -26.055 27.674  -33.287  1.00 51.99  ? 267 ILE I CG1 1 
ATOM   10032 C CG2 . ILE E 1 268 ? -23.803 28.406  -34.142  1.00 58.95  ? 267 ILE I CG2 1 
ATOM   10033 C CD1 . ILE E 1 268 ? -25.706 28.342  -31.985  1.00 69.73  ? 267 ILE I CD1 1 
ATOM   10034 N N   . MET E 1 269 ? -23.934 27.894  -37.339  1.00 54.75  ? 268 MET I N   1 
ATOM   10035 C CA  . MET E 1 269 ? -22.856 27.965  -38.313  1.00 56.54  ? 268 MET I CA  1 
ATOM   10036 C C   . MET E 1 269 ? -21.825 28.990  -37.865  1.00 60.95  ? 268 MET I C   1 
ATOM   10037 O O   . MET E 1 269 ? -22.175 30.128  -37.531  1.00 60.19  ? 268 MET I O   1 
ATOM   10038 C CB  . MET E 1 269 ? -23.392 28.327  -39.698  1.00 59.38  ? 268 MET I CB  1 
ATOM   10039 C CG  . MET E 1 269 ? -22.307 28.534  -40.738  1.00 60.46  ? 268 MET I CG  1 
ATOM   10040 S SD  . MET E 1 269 ? -22.974 28.785  -42.390  1.00 65.50  ? 268 MET I SD  1 
ATOM   10041 C CE  . MET E 1 269 ? -23.527 27.127  -42.787  1.00 55.99  ? 268 MET I CE  1 
ATOM   10042 N N   . LYS E 1 270 ? -20.559 28.582  -37.853  1.00 48.85  ? 269 LYS I N   1 
ATOM   10043 C CA  . LYS E 1 270 ? -19.450 29.475  -37.543  1.00 61.56  ? 269 LYS I CA  1 
ATOM   10044 C C   . LYS E 1 270 ? -18.884 30.001  -38.860  1.00 60.04  ? 269 LYS I C   1 
ATOM   10045 O O   . LYS E 1 270 ? -18.347 29.229  -39.663  1.00 59.41  ? 269 LYS I O   1 
ATOM   10046 C CB  . LYS E 1 270 ? -18.384 28.741  -36.734  1.00 48.45  ? 269 LYS I CB  1 
ATOM   10047 C CG  . LYS E 1 270 ? -18.849 28.263  -35.372  1.00 57.79  ? 269 LYS I CG  1 
ATOM   10048 C CD  . LYS E 1 270 ? -19.214 29.437  -34.479  1.00 72.74  ? 269 LYS I CD  1 
ATOM   10049 C CE  . LYS E 1 270 ? -18.853 29.165  -33.028  1.00 70.18  ? 269 LYS I CE  1 
ATOM   10050 N NZ  . LYS E 1 270 ? -18.951 30.398  -32.198  1.00 68.08  ? 269 LYS I NZ  1 
ATOM   10051 N N   . SER E 1 271 ? -19.007 31.306  -39.088  1.00 60.42  ? 270 SER I N   1 
ATOM   10052 C CA  . SER E 1 271 ? -18.505 31.893  -40.324  1.00 75.57  ? 270 SER I CA  1 
ATOM   10053 C C   . SER E 1 271 ? -18.394 33.402  -40.170  1.00 65.84  ? 270 SER I C   1 
ATOM   10054 O O   . SER E 1 271 ? -19.105 34.013  -39.369  1.00 70.22  ? 270 SER I O   1 
ATOM   10055 C CB  . SER E 1 271 ? -19.408 31.552  -41.516  1.00 74.64  ? 270 SER I CB  1 
ATOM   10056 O OG  . SER E 1 271 ? -18.873 32.070  -42.721  1.00 67.54  ? 270 SER I OG  1 
ATOM   10057 N N   . GLY E 1 272 ? -17.492 33.990  -40.954  1.00 76.78  ? 271 GLY I N   1 
ATOM   10058 C CA  . GLY E 1 272 ? -17.358 35.431  -41.028  1.00 63.44  ? 271 GLY I CA  1 
ATOM   10059 C C   . GLY E 1 272 ? -17.796 35.974  -42.374  1.00 82.14  ? 271 GLY I C   1 
ATOM   10060 O O   . GLY E 1 272 ? -17.759 37.185  -42.611  1.00 80.45  ? 271 GLY I O   1 
ATOM   10061 N N   . VAL E 1 273 ? -18.208 35.072  -43.268  1.00 74.81  ? 272 VAL I N   1 
ATOM   10062 C CA  . VAL E 1 273 ? -18.659 35.479  -44.591  1.00 67.59  ? 272 VAL I CA  1 
ATOM   10063 C C   . VAL E 1 273 ? -19.921 36.333  -44.469  1.00 78.38  ? 272 VAL I C   1 
ATOM   10064 O O   . VAL E 1 273 ? -20.762 36.125  -43.587  1.00 86.26  ? 272 VAL I O   1 
ATOM   10065 C CB  . VAL E 1 273 ? -18.895 34.242  -45.476  1.00 69.76  ? 272 VAL I CB  1 
ATOM   10066 C CG1 . VAL E 1 273 ? -19.362 34.642  -46.865  1.00 67.22  ? 272 VAL I CG1 1 
ATOM   10067 C CG2 . VAL E 1 273 ? -17.623 33.410  -45.565  1.00 67.51  ? 272 VAL I CG2 1 
ATOM   10068 N N   . GLU E 1 274 ? -20.043 37.312  -45.362  1.00 82.94  ? 273 GLU I N   1 
ATOM   10069 C CA  . GLU E 1 274 ? -21.098 38.313  -45.305  1.00 74.35  ? 273 GLU I CA  1 
ATOM   10070 C C   . GLU E 1 274 ? -22.381 37.825  -45.970  1.00 78.73  ? 273 GLU I C   1 
ATOM   10071 O O   . GLU E 1 274 ? -22.361 36.977  -46.867  1.00 75.52  ? 273 GLU I O   1 
ATOM   10072 C CB  . GLU E 1 274 ? -20.626 39.603  -45.976  1.00 86.59  ? 273 GLU I CB  1 
ATOM   10073 C CG  . GLU E 1 274 ? -19.947 39.366  -47.317  1.00 103.03 ? 273 GLU I CG  1 
ATOM   10074 C CD  . GLU E 1 274 ? -18.777 40.301  -47.553  1.00 127.18 ? 273 GLU I CD  1 
ATOM   10075 O OE1 . GLU E 1 274 ? -19.010 41.504  -47.795  1.00 116.22 ? 273 GLU I OE1 1 
ATOM   10076 O OE2 . GLU E 1 274 ? -17.620 39.830  -47.487  1.00 128.34 ? 273 GLU I OE2 1 
ATOM   10077 N N   . TYR E 1 275 ? -23.503 38.379  -45.513  1.00 62.56  ? 274 TYR I N   1 
ATOM   10078 C CA  . TYR E 1 275 ? -24.800 38.092  -46.111  1.00 75.88  ? 274 TYR I CA  1 
ATOM   10079 C C   . TYR E 1 275 ? -24.899 38.718  -47.499  1.00 80.57  ? 274 TYR I C   1 
ATOM   10080 O O   . TYR E 1 275 ? -24.447 39.845  -47.722  1.00 81.95  ? 274 TYR I O   1 
ATOM   10081 C CB  . TYR E 1 275 ? -25.914 38.618  -45.204  1.00 67.61  ? 274 TYR I CB  1 
ATOM   10082 C CG  . TYR E 1 275 ? -27.317 38.373  -45.709  1.00 81.50  ? 274 TYR I CG  1 
ATOM   10083 C CD1 . TYR E 1 275 ? -27.821 37.085  -45.820  1.00 78.89  ? 274 TYR I CD1 1 
ATOM   10084 C CD2 . TYR E 1 275 ? -28.147 39.433  -46.053  1.00 79.78  ? 274 TYR I CD2 1 
ATOM   10085 C CE1 . TYR E 1 275 ? -29.104 36.857  -46.275  1.00 72.61  ? 274 TYR I CE1 1 
ATOM   10086 C CE2 . TYR E 1 275 ? -29.434 39.215  -46.508  1.00 77.01  ? 274 TYR I CE2 1 
ATOM   10087 C CZ  . TYR E 1 275 ? -29.908 37.925  -46.617  1.00 80.26  ? 274 TYR I CZ  1 
ATOM   10088 O OH  . TYR E 1 275 ? -31.189 37.700  -47.068  1.00 80.96  ? 274 TYR I OH  1 
ATOM   10089 N N   . GLY E 1 276 ? -25.504 37.987  -48.434  1.00 69.89  ? 275 GLY I N   1 
ATOM   10090 C CA  . GLY E 1 276 ? -25.491 38.407  -49.823  1.00 74.47  ? 275 GLY I CA  1 
ATOM   10091 C C   . GLY E 1 276 ? -26.838 38.557  -50.503  1.00 82.35  ? 275 GLY I C   1 
ATOM   10092 O O   . GLY E 1 276 ? -26.900 38.642  -51.733  1.00 95.76  ? 275 GLY I O   1 
ATOM   10093 N N   . HIS E 1 277 ? -27.918 38.591  -49.720  1.00 79.42  ? 276 HIS I N   1 
ATOM   10094 C CA  . HIS E 1 277 ? -29.270 38.820  -50.240  1.00 85.63  ? 276 HIS I CA  1 
ATOM   10095 C C   . HIS E 1 277 ? -29.624 37.825  -51.344  1.00 87.58  ? 276 HIS I C   1 
ATOM   10096 O O   . HIS E 1 277 ? -30.218 38.177  -52.365  1.00 91.25  ? 276 HIS I O   1 
ATOM   10097 C CB  . HIS E 1 277 ? -29.429 40.259  -50.736  1.00 83.76  ? 276 HIS I CB  1 
ATOM   10098 C CG  . HIS E 1 277 ? -28.932 41.289  -49.770  1.00 86.24  ? 276 HIS I CG  1 
ATOM   10099 N ND1 . HIS E 1 277 ? -27.597 41.605  -49.640  1.00 91.21  ? 276 HIS I ND1 1 
ATOM   10100 C CD2 . HIS E 1 277 ? -29.592 42.075  -48.885  1.00 79.55  ? 276 HIS I CD2 1 
ATOM   10101 C CE1 . HIS E 1 277 ? -27.455 42.541  -48.718  1.00 81.07  ? 276 HIS I CE1 1 
ATOM   10102 N NE2 . HIS E 1 277 ? -28.650 42.844  -48.245  1.00 73.71  ? 276 HIS I NE2 1 
ATOM   10103 N N   . CYS E 1 278 ? -29.257 36.568  -51.133  1.00 83.79  ? 277 CYS I N   1 
ATOM   10104 C CA  . CYS E 1 278 ? -29.493 35.494  -52.086  1.00 81.30  ? 277 CYS I CA  1 
ATOM   10105 C C   . CYS E 1 278 ? -30.411 34.448  -51.453  1.00 77.51  ? 277 CYS I C   1 
ATOM   10106 O O   . CYS E 1 278 ? -30.939 34.635  -50.354  1.00 91.92  ? 277 CYS I O   1 
ATOM   10107 C CB  . CYS E 1 278 ? -28.160 34.896  -52.543  1.00 78.60  ? 277 CYS I CB  1 
ATOM   10108 S SG  . CYS E 1 278 ? -26.873 34.896  -51.260  1.00 110.86 ? 277 CYS I SG  1 
ATOM   10109 N N   . ASN E 1 279 ? -30.615 33.346  -52.170  1.00 81.36  ? 278 ASN I N   1 
ATOM   10110 C CA  . ASN E 1 279 ? -31.389 32.222  -51.667  1.00 75.70  ? 278 ASN I CA  1 
ATOM   10111 C C   . ASN E 1 279 ? -30.710 30.934  -52.102  1.00 79.82  ? 278 ASN I C   1 
ATOM   10112 O O   . ASN E 1 279 ? -30.057 30.885  -53.148  1.00 79.14  ? 278 ASN I O   1 
ATOM   10113 C CB  . ASN E 1 279 ? -32.840 32.259  -52.170  1.00 78.73  ? 278 ASN I CB  1 
ATOM   10114 C CG  . ASN E 1 279 ? -33.734 31.269  -51.449  1.00 70.00  ? 278 ASN I CG  1 
ATOM   10115 O OD1 . ASN E 1 279 ? -33.573 31.027  -50.253  1.00 77.61  ? 278 ASN I OD1 1 
ATOM   10116 N ND2 . ASN E 1 279 ? -34.680 30.688  -52.176  1.00 77.63  ? 278 ASN I ND2 1 
ATOM   10117 N N   . THR E 1 280 ? -30.866 29.891  -51.292  1.00 76.43  ? 279 THR I N   1 
ATOM   10118 C CA  . THR E 1 280 ? -30.213 28.619  -51.569  1.00 65.63  ? 279 THR I CA  1 
ATOM   10119 C C   . THR E 1 280 ? -30.963 27.507  -50.853  1.00 67.84  ? 279 THR I C   1 
ATOM   10120 O O   . THR E 1 280 ? -31.809 27.750  -49.989  1.00 73.94  ? 279 THR I O   1 
ATOM   10121 C CB  . THR E 1 280 ? -28.741 28.636  -51.138  1.00 69.56  ? 279 THR I CB  1 
ATOM   10122 O OG1 . THR E 1 280 ? -28.123 27.393  -51.492  1.00 77.94  ? 279 THR I OG1 1 
ATOM   10123 C CG2 . THR E 1 280 ? -28.630 28.832  -49.634  1.00 68.64  ? 279 THR I CG2 1 
ATOM   10124 N N   . LYS E 1 281 ? -30.644 26.273  -51.240  1.00 72.50  ? 280 LYS I N   1 
ATOM   10125 C CA  . LYS E 1 281 ? -31.087 25.092  -50.520  1.00 76.47  ? 280 LYS I CA  1 
ATOM   10126 C C   . LYS E 1 281 ? -29.940 24.348  -49.849  1.00 69.12  ? 280 LYS I C   1 
ATOM   10127 O O   . LYS E 1 281 ? -30.191 23.374  -49.131  1.00 74.19  ? 280 LYS I O   1 
ATOM   10128 C CB  . LYS E 1 281 ? -31.835 24.138  -51.463  1.00 70.36  ? 280 LYS I CB  1 
ATOM   10129 C CG  . LYS E 1 281 ? -30.971 23.527  -52.550  1.00 68.87  ? 280 LYS I CG  1 
ATOM   10130 C CD  . LYS E 1 281 ? -31.736 22.454  -53.304  1.00 72.57  ? 280 LYS I CD  1 
ATOM   10131 C CE  . LYS E 1 281 ? -30.809 21.354  -53.789  1.00 79.28  ? 280 LYS I CE  1 
ATOM   10132 N NZ  . LYS E 1 281 ? -31.519 20.047  -53.879  1.00 80.24  ? 280 LYS I NZ  1 
ATOM   10133 N N   . CYS E 1 282 ? -28.697 24.780  -50.064  1.00 70.54  ? 281 CYS I N   1 
ATOM   10134 C CA  . CYS E 1 282 ? -27.525 24.190  -49.425  1.00 62.99  ? 281 CYS I CA  1 
ATOM   10135 C C   . CYS E 1 282 ? -26.540 25.305  -49.110  1.00 65.09  ? 281 CYS I C   1 
ATOM   10136 O O   . CYS E 1 282 ? -26.128 26.042  -50.011  1.00 69.77  ? 281 CYS I O   1 
ATOM   10137 C CB  . CYS E 1 282 ? -26.875 23.131  -50.323  1.00 58.37  ? 281 CYS I CB  1 
ATOM   10138 S SG  . CYS E 1 282 ? -25.311 22.496  -49.686  1.00 78.65  ? 281 CYS I SG  1 
ATOM   10139 N N   . GLN E 1 283 ? -26.163 25.427  -47.839  1.00 64.74  ? 282 GLN I N   1 
ATOM   10140 C CA  . GLN E 1 283 ? -25.303 26.502  -47.362  1.00 58.87  ? 282 GLN I CA  1 
ATOM   10141 C C   . GLN E 1 283 ? -24.082 25.925  -46.658  1.00 66.96  ? 282 GLN I C   1 
ATOM   10142 O O   . GLN E 1 283 ? -24.187 24.941  -45.919  1.00 66.06  ? 282 GLN I O   1 
ATOM   10143 C CB  . GLN E 1 283 ? -26.066 27.430  -46.408  1.00 50.36  ? 282 GLN I CB  1 
ATOM   10144 C CG  . GLN E 1 283 ? -25.238 28.576  -45.851  1.00 62.42  ? 282 GLN I CG  1 
ATOM   10145 C CD  . GLN E 1 283 ? -24.952 29.647  -46.887  1.00 69.25  ? 282 GLN I CD  1 
ATOM   10146 O OE1 . GLN E 1 283 ? -25.868 30.276  -47.415  1.00 60.60  ? 282 GLN I OE1 1 
ATOM   10147 N NE2 . GLN E 1 283 ? -23.675 29.856  -47.184  1.00 62.77  ? 282 GLN I NE2 1 
ATOM   10148 N N   . THR E 1 284 ? -22.929 26.538  -46.892  1.00 60.24  ? 283 THR I N   1 
ATOM   10149 C CA  . THR E 1 284 ? -21.666 26.174  -46.276  1.00 59.06  ? 283 THR I CA  1 
ATOM   10150 C C   . THR E 1 284 ? -21.070 27.403  -45.609  1.00 67.02  ? 283 THR I C   1 
ATOM   10151 O O   . THR E 1 284 ? -21.453 28.536  -45.926  1.00 64.41  ? 283 THR I O   1 
ATOM   10152 C CB  . THR E 1 284 ? -20.671 25.612  -47.305  1.00 56.88  ? 283 THR I CB  1 
ATOM   10153 O OG1 . THR E 1 284 ? -20.125 26.685  -48.080  1.00 71.59  ? 283 THR I OG1 1 
ATOM   10154 C CG2 . THR E 1 284 ? -21.359 24.626  -48.233  1.00 52.14  ? 283 THR I CG2 1 
ATOM   10155 N N   . PRO E 1 285 ? -20.138 27.218  -44.669  1.00 60.12  ? 284 PRO I N   1 
ATOM   10156 C CA  . PRO E 1 285 ? -19.499 28.382  -44.032  1.00 62.99  ? 284 PRO I CA  1 
ATOM   10157 C C   . PRO E 1 285 ? -18.670 29.235  -44.983  1.00 76.05  ? 284 PRO I C   1 
ATOM   10158 O O   . PRO E 1 285 ? -18.270 30.340  -44.595  1.00 74.11  ? 284 PRO I O   1 
ATOM   10159 C CB  . PRO E 1 285 ? -18.617 27.751  -42.945  1.00 66.62  ? 284 PRO I CB  1 
ATOM   10160 C CG  . PRO E 1 285 ? -19.238 26.422  -42.681  1.00 62.45  ? 284 PRO I CG  1 
ATOM   10161 C CD  . PRO E 1 285 ? -19.757 25.958  -44.006  1.00 56.19  ? 284 PRO I CD  1 
ATOM   10162 N N   . VAL E 1 286 ? -18.389 28.764  -46.197  1.00 75.30  ? 285 VAL I N   1 
ATOM   10163 C CA  . VAL E 1 286 ? -17.645 29.549  -47.179  1.00 76.62  ? 285 VAL I CA  1 
ATOM   10164 C C   . VAL E 1 286 ? -18.514 30.045  -48.324  1.00 72.81  ? 285 VAL I C   1 
ATOM   10165 O O   . VAL E 1 286 ? -18.053 30.897  -49.102  1.00 75.51  ? 285 VAL I O   1 
ATOM   10166 C CB  . VAL E 1 286 ? -16.440 28.763  -47.739  1.00 73.06  ? 285 VAL I CB  1 
ATOM   10167 C CG1 . VAL E 1 286 ? -15.420 28.501  -46.645  1.00 60.38  ? 285 VAL I CG1 1 
ATOM   10168 C CG2 . VAL E 1 286 ? -16.902 27.460  -48.368  1.00 67.07  ? 285 VAL I CG2 1 
ATOM   10169 N N   . GLY E 1 287 ? -19.736 29.555  -48.459  1.00 73.47  ? 286 GLY I N   1 
ATOM   10170 C CA  . GLY E 1 287 ? -20.626 30.022  -49.502  1.00 56.51  ? 286 GLY I CA  1 
ATOM   10171 C C   . GLY E 1 287 ? -21.712 29.016  -49.796  1.00 68.03  ? 286 GLY I C   1 
ATOM   10172 O O   . GLY E 1 287 ? -21.619 27.832  -49.467  1.00 61.98  ? 286 GLY I O   1 
ATOM   10173 N N   . ALA E 1 288 ? -22.771 29.506  -50.436  1.00 67.31  ? 287 ALA I N   1 
ATOM   10174 C CA  . ALA E 1 288 ? -23.898 28.661  -50.793  1.00 64.48  ? 287 ALA I CA  1 
ATOM   10175 C C   . ALA E 1 288 ? -23.589 27.852  -52.050  1.00 68.76  ? 287 ALA I C   1 
ATOM   10176 O O   . ALA E 1 288 ? -22.706 28.191  -52.840  1.00 73.89  ? 287 ALA I O   1 
ATOM   10177 C CB  . ALA E 1 288 ? -25.156 29.503  -51.006  1.00 59.14  ? 287 ALA I CB  1 
ATOM   10178 N N   . ILE E 1 289 ? -24.342 26.770  -52.230  1.00 68.67  ? 288 ILE I N   1 
ATOM   10179 C CA  . ILE E 1 289 ? -24.164 25.855  -53.352  1.00 61.49  ? 288 ILE I CA  1 
ATOM   10180 C C   . ILE E 1 289 ? -25.460 25.796  -54.145  1.00 72.18  ? 288 ILE I C   1 
ATOM   10181 O O   . ILE E 1 289 ? -26.525 25.510  -53.584  1.00 69.99  ? 288 ILE I O   1 
ATOM   10182 C CB  . ILE E 1 289 ? -23.756 24.449  -52.878  1.00 73.51  ? 288 ILE I CB  1 
ATOM   10183 C CG1 . ILE E 1 289 ? -22.443 24.503  -52.098  1.00 70.99  ? 288 ILE I CG1 1 
ATOM   10184 C CG2 . ILE E 1 289 ? -23.636 23.502  -54.063  1.00 59.14  ? 288 ILE I CG2 1 
ATOM   10185 C CD1 . ILE E 1 289 ? -22.043 23.172  -51.498  1.00 74.25  ? 288 ILE I CD1 1 
ATOM   10186 N N   . ASN E 1 290 ? -25.367 26.063  -55.445  1.00 79.55  ? 289 ASN I N   1 
ATOM   10187 C CA  . ASN E 1 290 ? -26.476 25.899  -56.383  1.00 74.22  ? 289 ASN I CA  1 
ATOM   10188 C C   . ASN E 1 290 ? -26.063 24.803  -57.360  1.00 76.61  ? 289 ASN I C   1 
ATOM   10189 O O   . ASN E 1 290 ? -25.331 25.064  -58.319  1.00 80.40  ? 289 ASN I O   1 
ATOM   10190 C CB  . ASN E 1 290 ? -26.794 27.210  -57.102  1.00 72.28  ? 289 ASN I CB  1 
ATOM   10191 C CG  . ASN E 1 290 ? -27.995 27.096  -58.023  1.00 86.06  ? 289 ASN I CG  1 
ATOM   10192 O OD1 . ASN E 1 290 ? -28.755 26.130  -57.954  1.00 87.44  ? 289 ASN I OD1 1 
ATOM   10193 N ND2 . ASN E 1 290 ? -28.174 28.088  -58.890  1.00 88.67  ? 289 ASN I ND2 1 
ATOM   10194 N N   . SER E 1 291 ? -26.521 23.577  -57.114  1.00 73.02  ? 290 SER I N   1 
ATOM   10195 C CA  . SER E 1 291 ? -26.065 22.443  -57.904  1.00 67.39  ? 290 SER I CA  1 
ATOM   10196 C C   . SER E 1 291 ? -27.047 21.289  -57.776  1.00 72.65  ? 290 SER I C   1 
ATOM   10197 O O   . SER E 1 291 ? -27.862 21.235  -56.851  1.00 77.36  ? 290 SER I O   1 
ATOM   10198 C CB  . SER E 1 291 ? -24.667 21.991  -57.472  1.00 69.60  ? 290 SER I CB  1 
ATOM   10199 O OG  . SER E 1 291 ? -24.304 20.778  -58.109  1.00 66.84  ? 290 SER I OG  1 
ATOM   10200 N N   . SER E 1 292 ? -26.951 20.365  -58.730  1.00 71.15  ? 291 SER I N   1 
ATOM   10201 C CA  . SER E 1 292 ? -27.662 19.097  -58.679  1.00 70.69  ? 291 SER I CA  1 
ATOM   10202 C C   . SER E 1 292 ? -26.715 17.909  -58.614  1.00 72.79  ? 291 SER I C   1 
ATOM   10203 O O   . SER E 1 292 ? -27.177 16.763  -58.656  1.00 68.41  ? 291 SER I O   1 
ATOM   10204 C CB  . SER E 1 292 ? -28.587 18.949  -59.895  1.00 76.27  ? 291 SER I CB  1 
ATOM   10205 O OG  . SER E 1 292 ? -29.553 19.984  -59.935  1.00 85.45  ? 291 SER I OG  1 
ATOM   10206 N N   . MET E 1 293 ? -25.409 18.150  -58.515  1.00 63.78  ? 292 MET I N   1 
ATOM   10207 C CA  . MET E 1 293 ? -24.444 17.065  -58.512  1.00 64.20  ? 292 MET I CA  1 
ATOM   10208 C C   . MET E 1 293 ? -24.579 16.226  -57.242  1.00 77.81  ? 292 MET I C   1 
ATOM   10209 O O   . MET E 1 293 ? -24.970 16.734  -56.188  1.00 70.97  ? 292 MET I O   1 
ATOM   10210 C CB  . MET E 1 293 ? -23.023 17.609  -58.625  1.00 71.58  ? 292 MET I CB  1 
ATOM   10211 C CG  . MET E 1 293 ? -22.696 18.225  -59.977  1.00 91.35  ? 292 MET I CG  1 
ATOM   10212 S SD  . MET E 1 293 ? -23.246 17.211  -61.365  1.00 81.39  ? 292 MET I SD  1 
ATOM   10213 C CE  . MET E 1 293 ? -24.663 18.158  -61.920  1.00 77.35  ? 292 MET I CE  1 
ATOM   10214 N N   . PRO E 1 294 ? -24.273 14.928  -57.323  1.00 65.10  ? 293 PRO I N   1 
ATOM   10215 C CA  . PRO E 1 294 ? -24.360 14.073  -56.132  1.00 67.16  ? 293 PRO I CA  1 
ATOM   10216 C C   . PRO E 1 294 ? -23.178 14.198  -55.185  1.00 64.66  ? 293 PRO I C   1 
ATOM   10217 O O   . PRO E 1 294 ? -23.271 13.707  -54.051  1.00 72.81  ? 293 PRO I O   1 
ATOM   10218 C CB  . PRO E 1 294 ? -24.434 12.662  -56.729  1.00 76.31  ? 293 PRO I CB  1 
ATOM   10219 C CG  . PRO E 1 294 ? -23.673 12.773  -58.006  1.00 67.72  ? 293 PRO I CG  1 
ATOM   10220 C CD  . PRO E 1 294 ? -23.944 14.158  -58.536  1.00 66.59  ? 293 PRO I CD  1 
ATOM   10221 N N   . PHE E 1 295 ? -22.079 14.829  -55.597  1.00 61.26  ? 294 PHE I N   1 
ATOM   10222 C CA  . PHE E 1 295 ? -20.888 14.904  -54.765  1.00 59.57  ? 294 PHE I CA  1 
ATOM   10223 C C   . PHE E 1 295 ? -20.293 16.304  -54.824  1.00 69.75  ? 294 PHE I C   1 
ATOM   10224 O O   . PHE E 1 295 ? -20.488 17.041  -55.794  1.00 72.01  ? 294 PHE I O   1 
ATOM   10225 C CB  . PHE E 1 295 ? -19.843 13.863  -55.190  1.00 56.51  ? 294 PHE I CB  1 
ATOM   10226 C CG  . PHE E 1 295 ? -20.361 12.454  -55.189  1.00 68.49  ? 294 PHE I CG  1 
ATOM   10227 C CD1 . PHE E 1 295 ? -20.577 11.782  -53.995  1.00 62.68  ? 294 PHE I CD1 1 
ATOM   10228 C CD2 . PHE E 1 295 ? -20.635 11.801  -56.380  1.00 58.05  ? 294 PHE I CD2 1 
ATOM   10229 C CE1 . PHE E 1 295 ? -21.057 10.485  -53.989  1.00 54.98  ? 294 PHE I CE1 1 
ATOM   10230 C CE2 . PHE E 1 295 ? -21.114 10.503  -56.382  1.00 57.30  ? 294 PHE I CE2 1 
ATOM   10231 C CZ  . PHE E 1 295 ? -21.326 9.844   -55.184  1.00 75.75  ? 294 PHE I CZ  1 
ATOM   10232 N N   . HIS E 1 296 ? -19.565 16.661  -53.766  1.00 68.01  ? 295 HIS I N   1 
ATOM   10233 C CA  . HIS E 1 296 ? -18.906 17.957  -53.672  1.00 62.73  ? 295 HIS I CA  1 
ATOM   10234 C C   . HIS E 1 296 ? -17.742 17.839  -52.698  1.00 61.57  ? 295 HIS I C   1 
ATOM   10235 O O   . HIS E 1 296 ? -17.643 16.874  -51.936  1.00 60.58  ? 295 HIS I O   1 
ATOM   10236 C CB  . HIS E 1 296 ? -19.878 19.057  -53.230  1.00 66.02  ? 295 HIS I CB  1 
ATOM   10237 C CG  . HIS E 1 296 ? -20.079 19.130  -51.748  1.00 71.08  ? 295 HIS I CG  1 
ATOM   10238 N ND1 . HIS E 1 296 ? -19.657 20.203  -50.993  1.00 71.05  ? 295 HIS I ND1 1 
ATOM   10239 C CD2 . HIS E 1 296 ? -20.652 18.263  -50.881  1.00 61.03  ? 295 HIS I CD2 1 
ATOM   10240 C CE1 . HIS E 1 296 ? -19.964 19.995  -49.725  1.00 68.59  ? 295 HIS I CE1 1 
ATOM   10241 N NE2 . HIS E 1 296 ? -20.569 18.824  -49.630  1.00 74.53  ? 295 HIS I NE2 1 
ATOM   10242 N N   . ASN E 1 297 ? -16.854 18.839  -52.738  1.00 59.45  ? 296 ASN I N   1 
ATOM   10243 C CA  . ASN E 1 297 ? -15.658 18.833  -51.903  1.00 62.71  ? 296 ASN I CA  1 
ATOM   10244 C C   . ASN E 1 297 ? -15.403 20.202  -51.282  1.00 57.68  ? 296 ASN I C   1 
ATOM   10245 O O   . ASN E 1 297 ? -14.258 20.540  -50.961  1.00 55.82  ? 296 ASN I O   1 
ATOM   10246 C CB  . ASN E 1 297 ? -14.430 18.390  -52.705  1.00 68.30  ? 296 ASN I CB  1 
ATOM   10247 C CG  . ASN E 1 297 ? -14.031 19.397  -53.772  1.00 69.69  ? 296 ASN I CG  1 
ATOM   10248 O OD1 . ASN E 1 297 ? -14.845 20.205  -54.220  1.00 66.18  ? 296 ASN I OD1 1 
ATOM   10249 N ND2 . ASN E 1 297 ? -12.769 19.351  -54.184  1.00 79.31  ? 296 ASN I ND2 1 
ATOM   10250 N N   . ILE E 1 298 ? -16.456 20.993  -51.092  1.00 60.17  ? 297 ILE I N   1 
ATOM   10251 C CA  . ILE E 1 298 ? -16.284 22.385  -50.687  1.00 57.53  ? 297 ILE I CA  1 
ATOM   10252 C C   . ILE E 1 298 ? -16.053 22.492  -49.183  1.00 68.86  ? 297 ILE I C   1 
ATOM   10253 O O   . ILE E 1 298 ? -15.031 23.022  -48.733  1.00 71.32  ? 297 ILE I O   1 
ATOM   10254 C CB  . ILE E 1 298 ? -17.495 23.220  -51.140  1.00 63.12  ? 297 ILE I CB  1 
ATOM   10255 C CG1 . ILE E 1 298 ? -17.641 23.133  -52.662  1.00 57.78  ? 297 ILE I CG1 1 
ATOM   10256 C CG2 . ILE E 1 298 ? -17.348 24.663  -50.692  1.00 63.55  ? 297 ILE I CG2 1 
ATOM   10257 C CD1 . ILE E 1 298 ? -18.914 23.743  -53.199  1.00 62.65  ? 297 ILE I CD1 1 
ATOM   10258 N N   . HIS E 1 299 ? -16.994 21.988  -48.385  1.00 70.26  ? 298 HIS I N   1 
ATOM   10259 C CA  . HIS E 1 299 ? -16.900 22.087  -46.934  1.00 62.67  ? 298 HIS I CA  1 
ATOM   10260 C C   . HIS E 1 299 ? -17.788 21.016  -46.319  1.00 64.13  ? 298 HIS I C   1 
ATOM   10261 O O   . HIS E 1 299 ? -18.827 20.678  -46.897  1.00 66.39  ? 298 HIS I O   1 
ATOM   10262 C CB  . HIS E 1 299 ? -17.322 23.482  -46.449  1.00 66.27  ? 298 HIS I CB  1 
ATOM   10263 C CG  . HIS E 1 299 ? -16.745 23.863  -45.120  1.00 70.64  ? 298 HIS I CG  1 
ATOM   10264 N ND1 . HIS E 1 299 ? -17.347 23.534  -43.924  1.00 70.67  ? 298 HIS I ND1 1 
ATOM   10265 C CD2 . HIS E 1 299 ? -15.623 24.549  -44.800  1.00 69.68  ? 298 HIS I CD2 1 
ATOM   10266 C CE1 . HIS E 1 299 ? -16.618 23.998  -42.925  1.00 61.38  ? 298 HIS I CE1 1 
ATOM   10267 N NE2 . HIS E 1 299 ? -15.566 24.618  -43.429  1.00 68.95  ? 298 HIS I NE2 1 
ATOM   10268 N N   . PRO E 1 300 ? -17.408 20.455  -45.161  1.00 73.22  ? 299 PRO I N   1 
ATOM   10269 C CA  . PRO E 1 300 ? -18.240 19.414  -44.539  1.00 66.17  ? 299 PRO I CA  1 
ATOM   10270 C C   . PRO E 1 300 ? -19.368 19.952  -43.668  1.00 60.10  ? 299 PRO I C   1 
ATOM   10271 O O   . PRO E 1 300 ? -20.367 19.258  -43.450  1.00 59.86  ? 299 PRO I O   1 
ATOM   10272 C CB  . PRO E 1 300 ? -17.227 18.625  -43.700  1.00 65.09  ? 299 PRO I CB  1 
ATOM   10273 C CG  . PRO E 1 300 ? -16.206 19.639  -43.325  1.00 56.98  ? 299 PRO I CG  1 
ATOM   10274 C CD  . PRO E 1 300 ? -16.091 20.570  -44.509  1.00 70.70  ? 299 PRO I CD  1 
ATOM   10275 N N   . LEU E 1 301 ? -19.226 21.174  -43.157  1.00 55.97  ? 300 LEU I N   1 
ATOM   10276 C CA  . LEU E 1 301 ? -20.188 21.731  -42.203  1.00 58.82  ? 300 LEU I CA  1 
ATOM   10277 C C   . LEU E 1 301 ? -21.339 22.426  -42.932  1.00 56.91  ? 300 LEU I C   1 
ATOM   10278 O O   . LEU E 1 301 ? -21.595 23.621  -42.772  1.00 68.01  ? 300 LEU I O   1 
ATOM   10279 C CB  . LEU E 1 301 ? -19.486 22.685  -41.243  1.00 54.33  ? 300 LEU I CB  1 
ATOM   10280 C CG  . LEU E 1 301 ? -18.283 22.114  -40.492  1.00 59.34  ? 300 LEU I CG  1 
ATOM   10281 C CD1 . LEU E 1 301 ? -17.710 23.148  -39.531  1.00 44.02  ? 300 LEU I CD1 1 
ATOM   10282 C CD2 . LEU E 1 301 ? -18.664 20.838  -39.759  1.00 55.22  ? 300 LEU I CD2 1 
ATOM   10283 N N   . THR E 1 302 ? -22.054 21.638  -43.727  1.00 55.07  ? 301 THR I N   1 
ATOM   10284 C CA  . THR E 1 302 ? -23.132 22.152  -44.558  1.00 59.86  ? 301 THR I CA  1 
ATOM   10285 C C   . THR E 1 302 ? -24.474 22.081  -43.837  1.00 61.54  ? 301 THR I C   1 
ATOM   10286 O O   . THR E 1 302 ? -24.675 21.271  -42.928  1.00 63.00  ? 301 THR I O   1 
ATOM   10287 C CB  . THR E 1 302 ? -23.216 21.376  -45.874  1.00 63.86  ? 301 THR I CB  1 
ATOM   10288 O OG1 . THR E 1 302 ? -23.539 20.007  -45.602  1.00 60.62  ? 301 THR I OG1 1 
ATOM   10289 C CG2 . THR E 1 302 ? -21.892 21.438  -46.604  1.00 64.30  ? 301 THR I CG2 1 
ATOM   10290 N N   . ILE E 1 303 ? -25.387 22.958  -44.252  1.00 58.02  ? 302 ILE I N   1 
ATOM   10291 C CA  . ILE E 1 303 ? -26.756 22.994  -43.753  1.00 53.81  ? 302 ILE I CA  1 
ATOM   10292 C C   . ILE E 1 303 ? -27.691 22.973  -44.953  1.00 61.96  ? 302 ILE I C   1 
ATOM   10293 O O   . ILE E 1 303 ? -27.628 23.865  -45.810  1.00 59.66  ? 302 ILE I O   1 
ATOM   10294 C CB  . ILE E 1 303 ? -27.034 24.238  -42.894  1.00 55.66  ? 302 ILE I CB  1 
ATOM   10295 C CG1 . ILE E 1 303 ? -26.089 24.296  -41.691  1.00 58.01  ? 302 ILE I CG1 1 
ATOM   10296 C CG2 . ILE E 1 303 ? -28.492 24.245  -42.426  1.00 45.84  ? 302 ILE I CG2 1 
ATOM   10297 C CD1 . ILE E 1 303 ? -26.307 25.518  -40.815  1.00 54.70  ? 302 ILE I CD1 1 
ATOM   10298 N N   . GLY E 1 304 ? -28.560 21.970  -45.010  1.00 56.81  ? 303 GLY I N   1 
ATOM   10299 C CA  . GLY E 1 304 ? -29.587 21.877  -46.021  1.00 62.53  ? 303 GLY I CA  1 
ATOM   10300 C C   . GLY E 1 304 ? -29.454 20.605  -46.834  1.00 63.39  ? 303 GLY I C   1 
ATOM   10301 O O   . GLY E 1 304 ? -28.759 19.647  -46.455  1.00 74.08  ? 303 GLY I O   1 
ATOM   10302 N N   . GLU E 1 305 ? -30.147 20.601  -47.968  1.00 76.97  ? 304 GLU I N   1 
ATOM   10303 C CA  . GLU E 1 305 ? -30.111 19.494  -48.917  1.00 70.91  ? 304 GLU I CA  1 
ATOM   10304 C C   . GLU E 1 305 ? -28.883 19.673  -49.798  1.00 70.83  ? 304 GLU I C   1 
ATOM   10305 O O   . GLU E 1 305 ? -28.882 20.479  -50.731  1.00 75.99  ? 304 GLU I O   1 
ATOM   10306 C CB  . GLU E 1 305 ? -31.388 19.442  -49.748  1.00 74.24  ? 304 GLU I CB  1 
ATOM   10307 C CG  . GLU E 1 305 ? -32.665 19.500  -48.920  1.00 68.84  ? 304 GLU I CG  1 
ATOM   10308 C CD  . GLU E 1 305 ? -33.276 20.889  -48.885  1.00 87.18  ? 304 GLU I CD  1 
ATOM   10309 O OE1 . GLU E 1 305 ? -34.394 21.063  -49.417  1.00 80.23  ? 304 GLU I OE1 1 
ATOM   10310 O OE2 . GLU E 1 305 ? -32.637 21.809  -48.329  1.00 85.12  ? 304 GLU I OE2 1 
ATOM   10311 N N   . CYS E 1 306 ? -27.835 18.912  -49.513  1.00 69.27  ? 305 CYS I N   1 
ATOM   10312 C CA  . CYS E 1 306 ? -26.515 19.124  -50.077  1.00 61.79  ? 305 CYS I CA  1 
ATOM   10313 C C   . CYS E 1 306 ? -26.001 17.862  -50.752  1.00 63.71  ? 305 CYS I C   1 
ATOM   10314 O O   . CYS E 1 306 ? -26.423 16.749  -50.419  1.00 67.12  ? 305 CYS I O   1 
ATOM   10315 C CB  . CYS E 1 306 ? -25.524 19.554  -48.985  1.00 68.06  ? 305 CYS I CB  1 
ATOM   10316 S SG  . CYS E 1 306 ? -25.861 21.167  -48.246  1.00 83.96  ? 305 CYS I SG  1 
ATOM   10317 N N   . PRO E 1 307 ? -25.092 18.001  -51.713  1.00 67.28  ? 306 PRO I N   1 
ATOM   10318 C CA  . PRO E 1 307 ? -24.424 16.824  -52.275  1.00 64.58  ? 306 PRO I CA  1 
ATOM   10319 C C   . PRO E 1 307 ? -23.569 16.134  -51.226  1.00 68.36  ? 306 PRO I C   1 
ATOM   10320 O O   . PRO E 1 307 ? -23.150 16.730  -50.230  1.00 60.38  ? 306 PRO I O   1 
ATOM   10321 C CB  . PRO E 1 307 ? -23.556 17.405  -53.396  1.00 70.18  ? 306 PRO I CB  1 
ATOM   10322 C CG  . PRO E 1 307 ? -24.150 18.749  -53.693  1.00 73.77  ? 306 PRO I CG  1 
ATOM   10323 C CD  . PRO E 1 307 ? -24.692 19.243  -52.392  1.00 56.46  ? 306 PRO I CD  1 
ATOM   10324 N N   . LYS E 1 308 ? -23.327 14.848  -51.457  1.00 63.26  ? 307 LYS I N   1 
ATOM   10325 C CA  . LYS E 1 308 ? -22.523 14.064  -50.531  1.00 64.71  ? 307 LYS I CA  1 
ATOM   10326 C C   . LYS E 1 308 ? -21.079 14.555  -50.536  1.00 69.27  ? 307 LYS I C   1 
ATOM   10327 O O   . LYS E 1 308 ? -20.471 14.726  -51.596  1.00 67.50  ? 307 LYS I O   1 
ATOM   10328 C CB  . LYS E 1 308 ? -22.591 12.583  -50.899  1.00 51.41  ? 307 LYS I CB  1 
ATOM   10329 C CG  . LYS E 1 308 ? -23.986 11.993  -50.764  1.00 64.05  ? 307 LYS I CG  1 
ATOM   10330 C CD  . LYS E 1 308 ? -24.525 12.173  -49.349  1.00 59.86  ? 307 LYS I CD  1 
ATOM   10331 C CE  . LYS E 1 308 ? -25.988 11.768  -49.253  1.00 64.54  ? 307 LYS I CE  1 
ATOM   10332 N NZ  . LYS E 1 308 ? -26.860 12.633  -50.099  1.00 79.45  ? 307 LYS I NZ  1 
ATOM   10333 N N   . TYR E 1 309 ? -20.533 14.783  -49.345  1.00 56.44  ? 308 TYR I N   1 
ATOM   10334 C CA  . TYR E 1 309 ? -19.182 15.310  -49.211  1.00 62.72  ? 308 TYR I CA  1 
ATOM   10335 C C   . TYR E 1 309 ? -18.165 14.190  -49.397  1.00 57.36  ? 308 TYR I C   1 
ATOM   10336 O O   . TYR E 1 309 ? -18.269 13.134  -48.766  1.00 64.89  ? 308 TYR I O   1 
ATOM   10337 C CB  . TYR E 1 309 ? -19.014 15.977  -47.844  1.00 60.20  ? 308 TYR I CB  1 
ATOM   10338 C CG  . TYR E 1 309 ? -17.699 16.698  -47.648  1.00 62.89  ? 308 TYR I CG  1 
ATOM   10339 C CD1 . TYR E 1 309 ? -17.282 17.684  -48.533  1.00 69.38  ? 308 TYR I CD1 1 
ATOM   10340 C CD2 . TYR E 1 309 ? -16.887 16.411  -46.562  1.00 62.66  ? 308 TYR I CD2 1 
ATOM   10341 C CE1 . TYR E 1 309 ? -16.081 18.347  -48.352  1.00 58.34  ? 308 TYR I CE1 1 
ATOM   10342 C CE2 . TYR E 1 309 ? -15.684 17.065  -46.374  1.00 64.92  ? 308 TYR I CE2 1 
ATOM   10343 C CZ  . TYR E 1 309 ? -15.287 18.033  -47.269  1.00 58.23  ? 308 TYR I CZ  1 
ATOM   10344 O OH  . TYR E 1 309 ? -14.092 18.688  -47.076  1.00 68.28  ? 308 TYR I OH  1 
ATOM   10345 N N   . VAL E 1 310 ? -17.187 14.419  -50.275  1.00 61.26  ? 309 VAL I N   1 
ATOM   10346 C CA  . VAL E 1 310 ? -16.162 13.433  -50.587  1.00 68.45  ? 309 VAL I CA  1 
ATOM   10347 C C   . VAL E 1 310 ? -14.799 14.107  -50.572  1.00 61.17  ? 309 VAL I C   1 
ATOM   10348 O O   . VAL E 1 310 ? -14.681 15.334  -50.614  1.00 54.48  ? 309 VAL I O   1 
ATOM   10349 C CB  . VAL E 1 310 ? -16.390 12.750  -51.955  1.00 63.65  ? 309 VAL I CB  1 
ATOM   10350 C CG1 . VAL E 1 310 ? -17.659 11.918  -51.938  1.00 61.87  ? 309 VAL I CG1 1 
ATOM   10351 C CG2 . VAL E 1 310 ? -16.437 13.790  -53.064  1.00 63.53  ? 309 VAL I CG2 1 
ATOM   10352 N N   . LYS E 1 311 ? -13.759 13.278  -50.506  1.00 59.68  ? 310 LYS I N   1 
ATOM   10353 C CA  . LYS E 1 311 ? -12.379 13.728  -50.673  1.00 78.62  ? 310 LYS I CA  1 
ATOM   10354 C C   . LYS E 1 311 ? -11.980 13.408  -52.111  1.00 77.55  ? 310 LYS I C   1 
ATOM   10355 O O   . LYS E 1 311 ? -11.476 12.324  -52.410  1.00 94.70  ? 310 LYS I O   1 
ATOM   10356 C CB  . LYS E 1 311 ? -11.454 13.059  -49.663  1.00 74.07  ? 310 LYS I CB  1 
ATOM   10357 C CG  . LYS E 1 311 ? -10.243 13.901  -49.288  1.00 91.17  ? 310 LYS I CG  1 
ATOM   10358 C CD  . LYS E 1 311 ? -9.239  13.109  -48.465  1.00 97.21  ? 310 LYS I CD  1 
ATOM   10359 C CE  . LYS E 1 311 ? -8.328  12.284  -49.358  1.00 84.82  ? 310 LYS I CE  1 
ATOM   10360 N NZ  . LYS E 1 311 ? -7.501  13.153  -50.242  1.00 94.33  ? 310 LYS I NZ  1 
ATOM   10361 N N   . SER E 1 312 ? -12.227 14.357  -53.012  1.00 62.83  ? 311 SER I N   1 
ATOM   10362 C CA  . SER E 1 312 ? -11.913 14.182  -54.422  1.00 74.94  ? 311 SER I CA  1 
ATOM   10363 C C   . SER E 1 312 ? -11.646 15.540  -55.050  1.00 71.01  ? 311 SER I C   1 
ATOM   10364 O O   . SER E 1 312 ? -12.236 16.551  -54.657  1.00 73.42  ? 311 SER I O   1 
ATOM   10365 C CB  . SER E 1 312 ? -13.044 13.477  -55.181  1.00 61.02  ? 311 SER I CB  1 
ATOM   10366 O OG  . SER E 1 312 ? -13.186 12.133  -54.760  1.00 72.28  ? 311 SER I OG  1 
ATOM   10367 N N   . ASN E 1 313 ? -10.744 15.552  -56.030  1.00 78.96  ? 312 ASN I N   1 
ATOM   10368 C CA  . ASN E 1 313 ? -10.496 16.753  -56.815  1.00 81.28  ? 312 ASN I CA  1 
ATOM   10369 C C   . ASN E 1 313 ? -11.295 16.763  -58.109  1.00 83.04  ? 312 ASN I C   1 
ATOM   10370 O O   . ASN E 1 313 ? -11.616 17.840  -58.627  1.00 86.66  ? 312 ASN I O   1 
ATOM   10371 C CB  . ASN E 1 313 ? -9.003  16.887  -57.127  1.00 78.68  ? 312 ASN I CB  1 
ATOM   10372 C CG  . ASN E 1 313 ? -8.174  17.167  -55.890  1.00 94.30  ? 312 ASN I CG  1 
ATOM   10373 O OD1 . ASN E 1 313 ? -8.593  17.909  -55.001  1.00 82.62  ? 312 ASN I OD1 1 
ATOM   10374 N ND2 . ASN E 1 313 ? -6.988  16.571  -55.826  1.00 95.47  ? 312 ASN I ND2 1 
ATOM   10375 N N   . LYS E 1 314 ? -11.630 15.586  -58.637  1.00 86.32  ? 313 LYS I N   1 
ATOM   10376 C CA  . LYS E 1 314 ? -12.405 15.484  -59.864  1.00 90.80  ? 313 LYS I CA  1 
ATOM   10377 C C   . LYS E 1 314 ? -13.031 14.099  -59.940  1.00 75.07  ? 313 LYS I C   1 
ATOM   10378 O O   . LYS E 1 314 ? -12.404 13.105  -59.564  1.00 75.05  ? 313 LYS I O   1 
ATOM   10379 C CB  . LYS E 1 314 ? -11.533 15.743  -61.099  1.00 84.37  ? 313 LYS I CB  1 
ATOM   10380 C CG  . LYS E 1 314 ? -10.277 14.885  -61.160  1.00 92.09  ? 313 LYS I CG  1 
ATOM   10381 C CD  . LYS E 1 314 ? -9.470  15.162  -62.418  1.00 91.00  ? 313 LYS I CD  1 
ATOM   10382 C CE  . LYS E 1 314 ? -8.105  14.494  -62.351  1.00 95.11  ? 313 LYS I CE  1 
ATOM   10383 N NZ  . LYS E 1 314 ? -8.207  13.026  -62.124  1.00 91.62  ? 313 LYS I NZ  1 
ATOM   10384 N N   . LEU E 1 315 ? -14.275 14.050  -60.414  1.00 77.07  ? 314 LEU I N   1 
ATOM   10385 C CA  . LEU E 1 315 ? -14.964 12.803  -60.750  1.00 79.33  ? 314 LEU I CA  1 
ATOM   10386 C C   . LEU E 1 315 ? -15.517 12.986  -62.158  1.00 90.80  ? 314 LEU I C   1 
ATOM   10387 O O   . LEU E 1 315 ? -16.686 13.341  -62.334  1.00 81.58  ? 314 LEU I O   1 
ATOM   10388 C CB  . LEU E 1 315 ? -16.065 12.479  -59.753  1.00 76.69  ? 314 LEU I CB  1 
ATOM   10389 C CG  . LEU E 1 315 ? -15.658 11.849  -58.425  1.00 71.85  ? 314 LEU I CG  1 
ATOM   10390 C CD1 . LEU E 1 315 ? -16.897 11.332  -57.739  1.00 89.42  ? 314 LEU I CD1 1 
ATOM   10391 C CD2 . LEU E 1 315 ? -14.649 10.733  -58.635  1.00 72.32  ? 314 LEU I CD2 1 
ATOM   10392 N N   . VAL E 1 316 ? -14.683 12.722  -63.159  1.00 85.85  ? 315 VAL I N   1 
ATOM   10393 C CA  . VAL E 1 316 ? -15.009 13.015  -64.549  1.00 89.64  ? 315 VAL I CA  1 
ATOM   10394 C C   . VAL E 1 316 ? -15.515 11.747  -65.220  1.00 79.14  ? 315 VAL I C   1 
ATOM   10395 O O   . VAL E 1 316 ? -14.885 10.685  -65.130  1.00 78.91  ? 315 VAL I O   1 
ATOM   10396 C CB  . VAL E 1 316 ? -13.796 13.602  -65.292  1.00 97.32  ? 315 VAL I CB  1 
ATOM   10397 C CG1 . VAL E 1 316 ? -13.408 14.935  -64.674  1.00 85.33  ? 315 VAL I CG1 1 
ATOM   10398 C CG2 . VAL E 1 316 ? -12.615 12.642  -65.247  1.00 88.26  ? 315 VAL I CG2 1 
ATOM   10399 N N   . LEU E 1 317 ? -16.658 11.855  -65.887  1.00 79.67  ? 316 LEU I N   1 
ATOM   10400 C CA  . LEU E 1 317 ? -17.304 10.727  -66.539  1.00 93.79  ? 316 LEU I CA  1 
ATOM   10401 C C   . LEU E 1 317 ? -17.179 10.877  -68.049  1.00 89.75  ? 316 LEU I C   1 
ATOM   10402 O O   . LEU E 1 317 ? -17.448 11.953  -68.595  1.00 71.77  ? 316 LEU I O   1 
ATOM   10403 C CB  . LEU E 1 317 ? -18.775 10.633  -66.126  1.00 89.01  ? 316 LEU I CB  1 
ATOM   10404 C CG  . LEU E 1 317 ? -19.561 9.399   -66.568  1.00 105.56 ? 316 LEU I CG  1 
ATOM   10405 C CD1 . LEU E 1 317 ? -18.857 8.128   -66.133  1.00 97.31  ? 316 LEU I CD1 1 
ATOM   10406 C CD2 . LEU E 1 317 ? -20.969 9.443   -66.000  1.00 99.54  ? 316 LEU I CD2 1 
ATOM   10407 N N   . ALA E 1 318 ? -16.760 9.804   -68.715  1.00 91.43  ? 317 ALA I N   1 
ATOM   10408 C CA  . ALA E 1 318 ? -16.602 9.826   -70.162  1.00 88.64  ? 317 ALA I CA  1 
ATOM   10409 C C   . ALA E 1 318 ? -17.963 9.730   -70.838  1.00 91.03  ? 317 ALA I C   1 
ATOM   10410 O O   . ALA E 1 318 ? -18.752 8.827   -70.545  1.00 84.51  ? 317 ALA I O   1 
ATOM   10411 C CB  . ALA E 1 318 ? -15.702 8.678   -70.620  1.00 80.46  ? 317 ALA I CB  1 
ATOM   10412 N N   . THR E 1 319 ? -18.238 10.671  -71.736  1.00 96.16  ? 318 THR I N   1 
ATOM   10413 C CA  . THR E 1 319 ? -19.444 10.650  -72.549  1.00 99.17  ? 318 THR I CA  1 
ATOM   10414 C C   . THR E 1 319 ? -19.167 10.488  -74.035  1.00 102.82 ? 318 THR I C   1 
ATOM   10415 O O   . THR E 1 319 ? -19.952 9.833   -74.724  1.00 105.79 ? 318 THR I O   1 
ATOM   10416 C CB  . THR E 1 319 ? -20.265 11.934  -72.337  1.00 98.94  ? 318 THR I CB  1 
ATOM   10417 O OG1 . THR E 1 319 ? -19.484 13.074  -72.716  1.00 89.19  ? 318 THR I OG1 1 
ATOM   10418 C CG2 . THR E 1 319 ? -20.677 12.068  -70.877  1.00 94.87  ? 318 THR I CG2 1 
ATOM   10419 N N   . GLY E 1 320 ? -18.079 11.058  -74.542  1.00 102.58 ? 319 GLY I N   1 
ATOM   10420 C CA  . GLY E 1 320 ? -17.705 10.925  -75.935  1.00 104.86 ? 319 GLY I CA  1 
ATOM   10421 C C   . GLY E 1 320 ? -16.754 9.771   -76.172  1.00 99.51  ? 319 GLY I C   1 
ATOM   10422 O O   . GLY E 1 320 ? -16.624 8.855   -75.356  1.00 94.42  ? 319 GLY I O   1 
ATOM   10423 N N   . LEU E 1 321 ? -16.072 9.827   -77.310  1.00 104.84 ? 320 LEU I N   1 
ATOM   10424 C CA  . LEU E 1 321 ? -15.178 8.763   -77.740  1.00 103.06 ? 320 LEU I CA  1 
ATOM   10425 C C   . LEU E 1 321 ? -13.725 9.117   -77.444  1.00 91.90  ? 320 LEU I C   1 
ATOM   10426 O O   . LEU E 1 321 ? -13.377 10.274  -77.196  1.00 90.88  ? 320 LEU I O   1 
ATOM   10427 C CB  . LEU E 1 321 ? -15.350 8.479   -79.235  1.00 103.31 ? 320 LEU I CB  1 
ATOM   10428 C CG  . LEU E 1 321 ? -16.781 8.300   -79.750  1.00 110.23 ? 320 LEU I CG  1 
ATOM   10429 C CD1 . LEU E 1 321 ? -17.309 9.596   -80.352  1.00 105.68 ? 320 LEU I CD1 1 
ATOM   10430 C CD2 . LEU E 1 321 ? -16.859 7.161   -80.754  1.00 110.90 ? 320 LEU I CD2 1 
ATOM   10431 N N   . ARG E 1 322 ? -12.877 8.092   -77.475  1.00 88.61  ? 321 ARG I N   1 
ATOM   10432 C CA  . ARG E 1 322 ? -11.448 8.258   -77.240  1.00 89.75  ? 321 ARG I CA  1 
ATOM   10433 C C   . ARG E 1 322 ? -10.849 9.081   -78.374  1.00 99.93  ? 321 ARG I C   1 
ATOM   10434 O O   . ARG E 1 322 ? -10.808 8.630   -79.525  1.00 112.30 ? 321 ARG I O   1 
ATOM   10435 C CB  . ARG E 1 322 ? -10.783 6.887   -77.137  1.00 86.13  ? 321 ARG I CB  1 
ATOM   10436 C CG  . ARG E 1 322 ? -11.722 5.809   -76.620  1.00 84.72  ? 321 ARG I CG  1 
ATOM   10437 C CD  . ARG E 1 322 ? -11.054 4.449   -76.522  1.00 79.82  ? 321 ARG I CD  1 
ATOM   10438 N NE  . ARG E 1 322 ? -9.995  4.427   -75.522  1.00 90.86  ? 321 ARG I NE  1 
ATOM   10439 C CZ  . ARG E 1 322 ? -9.655  3.357   -74.817  1.00 94.87  ? 321 ARG I CZ  1 
ATOM   10440 N NH1 . ARG E 1 322 ? -10.291 2.205   -74.959  1.00 92.34  ? 321 ARG I NH1 1 
ATOM   10441 N NH2 . ARG E 1 322 ? -8.659  3.446   -73.941  1.00 97.74  ? 321 ARG I NH2 1 
ATOM   10442 N N   . ASN E 1 323 ? -10.382 10.284  -78.057  1.00 106.13 ? 322 ASN I N   1 
ATOM   10443 C CA  . ASN E 1 323 ? -9.901  11.228  -79.057  1.00 99.11  ? 322 ASN I CA  1 
ATOM   10444 C C   . ASN E 1 323 ? -8.386  11.126  -79.176  1.00 111.40 ? 322 ASN I C   1 
ATOM   10445 O O   . ASN E 1 323 ? -7.667  11.290  -78.184  1.00 113.35 ? 322 ASN I O   1 
ATOM   10446 C CB  . ASN E 1 323 ? -10.312 12.656  -78.704  1.00 104.94 ? 322 ASN I CB  1 
ATOM   10447 C CG  . ASN E 1 323 ? -9.783  13.673  -79.697  1.00 116.23 ? 322 ASN I CG  1 
ATOM   10448 O OD1 . ASN E 1 323 ? -10.236 13.732  -80.841  1.00 108.97 ? 322 ASN I OD1 1 
ATOM   10449 N ND2 . ASN E 1 323 ? -8.824  14.483  -79.263  1.00 114.67 ? 322 ASN I ND2 1 
ATOM   10450 N N   . SER E 1 324 ? -7.907  10.863  -80.394  1.00 120.52 ? 323 SER I N   1 
ATOM   10451 C CA  . SER E 1 324 ? -6.492  10.799  -80.712  1.00 122.68 ? 323 SER I CA  1 
ATOM   10452 C C   . SER E 1 324 ? -6.076  12.019  -81.526  1.00 126.46 ? 323 SER I C   1 
ATOM   10453 O O   . SER E 1 324 ? -6.857  12.507  -82.350  1.00 119.86 ? 323 SER I O   1 
ATOM   10454 C CB  . SER E 1 324 ? -6.165  9.526   -81.504  1.00 115.48 ? 323 SER I CB  1 
ATOM   10455 O OG  . SER E 1 324 ? -4.795  9.478   -81.859  1.00 125.77 ? 323 SER I OG  1 
ATOM   10456 N N   . PRO E 1 325 ? -4.858  12.542  -81.314  1.00 139.49 ? 324 PRO I N   1 
ATOM   10457 C CA  . PRO E 1 325 ? -4.373  13.697  -82.077  1.00 133.07 ? 324 PRO I CA  1 
ATOM   10458 C C   . PRO E 1 325 ? -3.821  13.305  -83.445  1.00 126.58 ? 324 PRO I C   1 
ATOM   10459 O O   . PRO E 1 325 ? -4.000  14.060  -84.401  1.00 124.59 ? 324 PRO I O   1 
ATOM   10460 C CB  . PRO E 1 325 ? -3.268  14.258  -81.183  1.00 128.94 ? 324 PRO I CB  1 
ATOM   10461 C CG  . PRO E 1 325 ? -2.732  13.059  -80.480  1.00 129.32 ? 324 PRO I CG  1 
ATOM   10462 C CD  . PRO E 1 325 ? -3.911  12.142  -80.258  1.00 131.55 ? 324 PRO I CD  1 
ATOM   10463 N N   . GLY F 2 1   ? -10.441 -1.118  -77.118  1.00 139.06 ? 1   GLY J N   1 
ATOM   10464 C CA  . GLY F 2 1   ? -11.371 -1.655  -76.142  1.00 137.22 ? 1   GLY J CA  1 
ATOM   10465 C C   . GLY F 2 1   ? -11.528 -3.160  -76.231  1.00 144.31 ? 1   GLY J C   1 
ATOM   10466 O O   . GLY F 2 1   ? -10.654 -3.853  -76.750  1.00 151.30 ? 1   GLY J O   1 
ATOM   10467 N N   . LEU F 2 2   ? -12.651 -3.670  -75.716  1.00 141.53 ? 2   LEU J N   1 
ATOM   10468 C CA  . LEU F 2 2   ? -12.887 -5.111  -75.744  1.00 150.11 ? 2   LEU J CA  1 
ATOM   10469 C C   . LEU F 2 2   ? -13.228 -5.597  -77.148  1.00 148.23 ? 2   LEU J C   1 
ATOM   10470 O O   . LEU F 2 2   ? -12.753 -6.656  -77.576  1.00 141.91 ? 2   LEU J O   1 
ATOM   10471 C CB  . LEU F 2 2   ? -14.005 -5.485  -74.770  1.00 145.43 ? 2   LEU J CB  1 
ATOM   10472 C CG  . LEU F 2 2   ? -13.680 -5.498  -73.276  1.00 133.66 ? 2   LEU J CG  1 
ATOM   10473 C CD1 . LEU F 2 2   ? -14.860 -6.034  -72.475  1.00 124.75 ? 2   LEU J CD1 1 
ATOM   10474 C CD2 . LEU F 2 2   ? -12.428 -6.307  -73.000  1.00 127.75 ? 2   LEU J CD2 1 
ATOM   10475 N N   . PHE F 2 3   ? -14.047 -4.842  -77.877  1.00 145.29 ? 3   PHE J N   1 
ATOM   10476 C CA  . PHE F 2 3   ? -14.559 -5.290  -79.166  1.00 146.62 ? 3   PHE J CA  1 
ATOM   10477 C C   . PHE F 2 3   ? -13.588 -5.046  -80.314  1.00 155.71 ? 3   PHE J C   1 
ATOM   10478 O O   . PHE F 2 3   ? -13.881 -5.451  -81.444  1.00 154.70 ? 3   PHE J O   1 
ATOM   10479 C CB  . PHE F 2 3   ? -15.900 -4.609  -79.458  1.00 138.27 ? 3   PHE J CB  1 
ATOM   10480 C CG  . PHE F 2 3   ? -16.953 -4.870  -78.414  1.00 144.33 ? 3   PHE J CG  1 
ATOM   10481 C CD1 . PHE F 2 3   ? -17.013 -4.102  -77.261  1.00 141.87 ? 3   PHE J CD1 1 
ATOM   10482 C CD2 . PHE F 2 3   ? -17.882 -5.884  -78.585  1.00 145.98 ? 3   PHE J CD2 1 
ATOM   10483 C CE1 . PHE F 2 3   ? -17.977 -4.342  -76.298  1.00 138.58 ? 3   PHE J CE1 1 
ATOM   10484 C CE2 . PHE F 2 3   ? -18.851 -6.127  -77.627  1.00 142.79 ? 3   PHE J CE2 1 
ATOM   10485 C CZ  . PHE F 2 3   ? -18.898 -5.354  -76.482  1.00 138.60 ? 3   PHE J CZ  1 
ATOM   10486 N N   . GLY F 2 4   ? -12.450 -4.404  -80.056  1.00 157.07 ? 4   GLY J N   1 
ATOM   10487 C CA  . GLY F 2 4   ? -11.418 -4.233  -81.060  1.00 154.61 ? 4   GLY J CA  1 
ATOM   10488 C C   . GLY F 2 4   ? -11.814 -3.390  -82.255  1.00 162.73 ? 4   GLY J C   1 
ATOM   10489 O O   . GLY F 2 4   ? -11.553 -3.771  -83.400  1.00 165.10 ? 4   GLY J O   1 
ATOM   10490 N N   . ALA F 2 5   ? -12.444 -2.243  -82.008  1.00 162.76 ? 5   ALA J N   1 
ATOM   10491 C CA  . ALA F 2 5   ? -12.835 -1.333  -83.076  1.00 161.70 ? 5   ALA J CA  1 
ATOM   10492 C C   . ALA F 2 5   ? -12.226 0.056   -82.957  1.00 166.40 ? 5   ALA J C   1 
ATOM   10493 O O   . ALA F 2 5   ? -11.986 0.693   -83.985  1.00 168.53 ? 5   ALA J O   1 
ATOM   10494 C CB  . ALA F 2 5   ? -14.365 -1.200  -83.138  1.00 146.92 ? 5   ALA J CB  1 
ATOM   10495 N N   . ILE F 2 6   ? -11.976 0.545   -81.741  1.00 164.58 ? 6   ILE J N   1 
ATOM   10496 C CA  . ILE F 2 6   ? -11.332 1.845   -81.588  1.00 163.83 ? 6   ILE J CA  1 
ATOM   10497 C C   . ILE F 2 6   ? -9.823  1.722   -81.758  1.00 164.54 ? 6   ILE J C   1 
ATOM   10498 O O   . ILE F 2 6   ? -9.184  2.578   -82.379  1.00 158.76 ? 6   ILE J O   1 
ATOM   10499 C CB  . ILE F 2 6   ? -11.703 2.469   -80.230  1.00 152.88 ? 6   ILE J CB  1 
ATOM   10500 C CG1 . ILE F 2 6   ? -13.222 2.528   -80.062  1.00 144.86 ? 6   ILE J CG1 1 
ATOM   10501 C CG2 . ILE F 2 6   ? -11.108 3.864   -80.108  1.00 135.88 ? 6   ILE J CG2 1 
ATOM   10502 C CD1 . ILE F 2 6   ? -13.916 3.429   -81.061  1.00 138.15 ? 6   ILE J CD1 1 
ATOM   10503 N N   . ALA F 2 7   ? -9.229  0.661   -81.210  1.00 167.86 ? 7   ALA J N   1 
ATOM   10504 C CA  . ALA F 2 7   ? -7.798  0.407   -81.324  1.00 163.59 ? 7   ALA J CA  1 
ATOM   10505 C C   . ALA F 2 7   ? -7.523  -0.929  -82.007  1.00 168.78 ? 7   ALA J C   1 
ATOM   10506 O O   . ALA F 2 7   ? -6.536  -1.601  -81.701  1.00 169.15 ? 7   ALA J O   1 
ATOM   10507 C CB  . ALA F 2 7   ? -7.128  0.455   -79.952  1.00 159.34 ? 7   ALA J CB  1 
ATOM   10508 N N   . GLY F 2 8   ? -8.391  -1.324  -82.936  1.00 169.93 ? 8   GLY J N   1 
ATOM   10509 C CA  . GLY F 2 8   ? -8.229  -2.581  -83.640  1.00 169.72 ? 8   GLY J CA  1 
ATOM   10510 C C   . GLY F 2 8   ? -7.909  -2.407  -85.110  1.00 173.10 ? 8   GLY J C   1 
ATOM   10511 O O   . GLY F 2 8   ? -6.817  -1.952  -85.464  1.00 171.51 ? 8   GLY J O   1 
ATOM   10512 N N   . PHE F 2 9   ? -8.855  -2.771  -85.980  1.00 172.67 ? 9   PHE J N   1 
ATOM   10513 C CA  . PHE F 2 9   ? -8.632  -2.619  -87.414  1.00 169.41 ? 9   PHE J CA  1 
ATOM   10514 C C   . PHE F 2 9   ? -8.687  -1.158  -87.843  1.00 165.53 ? 9   PHE J C   1 
ATOM   10515 O O   . PHE F 2 9   ? -7.948  -0.752  -88.747  1.00 160.76 ? 9   PHE J O   1 
ATOM   10516 C CB  . PHE F 2 9   ? -9.646  -3.453  -88.201  1.00 165.93 ? 9   PHE J CB  1 
ATOM   10517 C CG  . PHE F 2 9   ? -11.023 -3.475  -87.595  1.00 167.11 ? 9   PHE J CG  1 
ATOM   10518 C CD1 . PHE F 2 9   ? -11.920 -2.450  -87.840  1.00 159.88 ? 9   PHE J CD1 1 
ATOM   10519 C CD2 . PHE F 2 9   ? -11.424 -4.532  -86.793  1.00 160.04 ? 9   PHE J CD2 1 
ATOM   10520 C CE1 . PHE F 2 9   ? -13.188 -2.470  -87.288  1.00 151.54 ? 9   PHE J CE1 1 
ATOM   10521 C CE2 . PHE F 2 9   ? -12.691 -4.558  -86.239  1.00 151.62 ? 9   PHE J CE2 1 
ATOM   10522 C CZ  . PHE F 2 9   ? -13.573 -3.526  -86.487  1.00 149.33 ? 9   PHE J CZ  1 
ATOM   10523 N N   . ILE F 2 10  ? -9.543  -0.357  -87.215  1.00 164.02 ? 10  ILE J N   1 
ATOM   10524 C CA  . ILE F 2 10  ? -9.626  1.071   -87.501  1.00 158.79 ? 10  ILE J CA  1 
ATOM   10525 C C   . ILE F 2 10  ? -8.579  1.777   -86.648  1.00 163.97 ? 10  ILE J C   1 
ATOM   10526 O O   . ILE F 2 10  ? -8.689  1.820   -85.420  1.00 169.63 ? 10  ILE J O   1 
ATOM   10527 C CB  . ILE F 2 10  ? -11.030 1.623   -87.227  1.00 149.16 ? 10  ILE J CB  1 
ATOM   10528 C CG1 . ILE F 2 10  ? -12.051 0.967   -88.156  1.00 152.02 ? 10  ILE J CG1 1 
ATOM   10529 C CG2 . ILE F 2 10  ? -11.050 3.135   -87.400  1.00 139.26 ? 10  ILE J CG2 1 
ATOM   10530 C CD1 . ILE F 2 10  ? -13.483 1.273   -87.798  1.00 133.34 ? 10  ILE J CD1 1 
ATOM   10531 N N   . GLU F 2 11  ? -7.562  2.335   -87.299  1.00 157.52 ? 11  GLU J N   1 
ATOM   10532 C CA  . GLU F 2 11  ? -6.491  3.064   -86.630  1.00 153.63 ? 11  GLU J CA  1 
ATOM   10533 C C   . GLU F 2 11  ? -6.579  4.556   -86.932  1.00 143.16 ? 11  GLU J C   1 
ATOM   10534 O O   . GLU F 2 11  ? -5.568  5.227   -87.147  1.00 140.37 ? 11  GLU J O   1 
ATOM   10535 C CB  . GLU F 2 11  ? -5.125  2.512   -87.031  1.00 153.26 ? 11  GLU J CB  1 
ATOM   10536 C CG  . GLU F 2 11  ? -4.985  1.009   -86.839  1.00 150.97 ? 11  GLU J CG  1 
ATOM   10537 C CD  . GLU F 2 11  ? -3.546  0.539   -86.930  1.00 142.79 ? 11  GLU J CD  1 
ATOM   10538 O OE1 . GLU F 2 11  ? -2.638  1.332   -86.604  1.00 138.13 ? 11  GLU J OE1 1 
ATOM   10539 O OE2 . GLU F 2 11  ? -3.323  -0.624  -87.329  1.00 133.17 ? 11  GLU J OE2 1 
ATOM   10540 N N   . GLY F 2 12  ? -7.798  5.088   -86.952  1.00 140.92 ? 12  GLY J N   1 
ATOM   10541 C CA  . GLY F 2 12  ? -8.011  6.467   -87.339  1.00 139.08 ? 12  GLY J CA  1 
ATOM   10542 C C   . GLY F 2 12  ? -8.784  7.305   -86.341  1.00 128.41 ? 12  GLY J C   1 
ATOM   10543 O O   . GLY F 2 12  ? -8.385  7.442   -85.181  1.00 126.48 ? 12  GLY J O   1 
ATOM   10544 N N   . GLY F 2 13  ? -9.903  7.862   -86.791  1.00 120.09 ? 13  GLY J N   1 
ATOM   10545 C CA  . GLY F 2 13  ? -10.609 8.893   -86.057  1.00 111.25 ? 13  GLY J CA  1 
ATOM   10546 C C   . GLY F 2 13  ? -10.619 10.165  -86.877  1.00 120.79 ? 13  GLY J C   1 
ATOM   10547 O O   . GLY F 2 13  ? -9.592  10.839  -87.005  1.00 121.20 ? 13  GLY J O   1 
ATOM   10548 N N   . TRP F 2 14  ? -11.775 10.505  -87.439  1.00 117.19 ? 14  TRP J N   1 
ATOM   10549 C CA  . TRP F 2 14  ? -11.869 11.504  -88.498  1.00 117.68 ? 14  TRP J CA  1 
ATOM   10550 C C   . TRP F 2 14  ? -12.226 12.855  -87.890  1.00 110.34 ? 14  TRP J C   1 
ATOM   10551 O O   . TRP F 2 14  ? -13.339 13.046  -87.390  1.00 104.65 ? 14  TRP J O   1 
ATOM   10552 C CB  . TRP F 2 14  ? -12.898 11.073  -89.542  1.00 127.53 ? 14  TRP J CB  1 
ATOM   10553 C CG  . TRP F 2 14  ? -12.658 9.683   -90.071  1.00 129.08 ? 14  TRP J CG  1 
ATOM   10554 C CD1 . TRP F 2 14  ? -11.486 8.980   -90.033  1.00 129.16 ? 14  TRP J CD1 1 
ATOM   10555 C CD2 . TRP F 2 14  ? -13.618 8.824   -90.700  1.00 131.08 ? 14  TRP J CD2 1 
ATOM   10556 N NE1 . TRP F 2 14  ? -11.656 7.743   -90.604  1.00 123.62 ? 14  TRP J NE1 1 
ATOM   10557 C CE2 . TRP F 2 14  ? -12.956 7.622   -91.021  1.00 128.76 ? 14  TRP J CE2 1 
ATOM   10558 C CE3 . TRP F 2 14  ? -14.971 8.957   -91.025  1.00 136.63 ? 14  TRP J CE3 1 
ATOM   10559 C CZ2 . TRP F 2 14  ? -13.600 6.560   -91.653  1.00 133.68 ? 14  TRP J CZ2 1 
ATOM   10560 C CZ3 . TRP F 2 14  ? -15.610 7.901   -91.651  1.00 134.05 ? 14  TRP J CZ3 1 
ATOM   10561 C CH2 . TRP F 2 14  ? -14.924 6.719   -91.957  1.00 137.57 ? 14  TRP J CH2 1 
ATOM   10562 N N   . GLN F 2 15  ? -11.276 13.792  -87.941  1.00 118.17 ? 15  GLN J N   1 
ATOM   10563 C CA  . GLN F 2 15  ? -11.532 15.145  -87.458  1.00 118.62 ? 15  GLN J CA  1 
ATOM   10564 C C   . GLN F 2 15  ? -12.566 15.851  -88.323  1.00 112.94 ? 15  GLN J C   1 
ATOM   10565 O O   . GLN F 2 15  ? -13.385 16.627  -87.816  1.00 111.29 ? 15  GLN J O   1 
ATOM   10566 C CB  . GLN F 2 15  ? -10.230 15.945  -87.426  1.00 120.45 ? 15  GLN J CB  1 
ATOM   10567 C CG  . GLN F 2 15  ? -9.142  15.335  -86.557  1.00 114.70 ? 15  GLN J CG  1 
ATOM   10568 C CD  . GLN F 2 15  ? -8.876  16.144  -85.301  1.00 112.07 ? 15  GLN J CD  1 
ATOM   10569 O OE1 . GLN F 2 15  ? -9.554  17.136  -85.032  1.00 111.91 ? 15  GLN J OE1 1 
ATOM   10570 N NE2 . GLN F 2 15  ? -7.881  15.724  -84.527  1.00 107.67 ? 15  GLN J NE2 1 
ATOM   10571 N N   . GLY F 2 16  ? -12.543 15.596  -89.632  1.00 124.48 ? 16  GLY J N   1 
ATOM   10572 C CA  . GLY F 2 16  ? -13.514 16.184  -90.537  1.00 127.94 ? 16  GLY J CA  1 
ATOM   10573 C C   . GLY F 2 16  ? -14.945 15.763  -90.276  1.00 129.61 ? 16  GLY J C   1 
ATOM   10574 O O   . GLY F 2 16  ? -15.865 16.381  -90.824  1.00 128.82 ? 16  GLY J O   1 
ATOM   10575 N N   . MET F 2 17  ? -15.158 14.728  -89.466  1.00 131.27 ? 17  MET J N   1 
ATOM   10576 C CA  . MET F 2 17  ? -16.503 14.328  -89.065  1.00 130.74 ? 17  MET J CA  1 
ATOM   10577 C C   . MET F 2 17  ? -16.967 15.233  -87.931  1.00 133.16 ? 17  MET J C   1 
ATOM   10578 O O   . MET F 2 17  ? -16.438 15.165  -86.817  1.00 136.71 ? 17  MET J O   1 
ATOM   10579 C CB  . MET F 2 17  ? -16.524 12.867  -88.640  1.00 129.46 ? 17  MET J CB  1 
ATOM   10580 C CG  . MET F 2 17  ? -17.826 12.422  -87.989  1.00 129.64 ? 17  MET J CG  1 
ATOM   10581 S SD  . MET F 2 17  ? -19.186 12.022  -89.117  1.00 128.61 ? 17  MET J SD  1 
ATOM   10582 C CE  . MET F 2 17  ? -19.884 13.633  -89.446  1.00 119.95 ? 17  MET J CE  1 
ATOM   10583 N N   . VAL F 2 18  ? -17.957 16.080  -88.218  1.00 132.19 ? 18  VAL J N   1 
ATOM   10584 C CA  . VAL F 2 18  ? -18.397 17.107  -87.278  1.00 132.27 ? 18  VAL J CA  1 
ATOM   10585 C C   . VAL F 2 18  ? -19.908 17.139  -87.083  1.00 126.55 ? 18  VAL J C   1 
ATOM   10586 O O   . VAL F 2 18  ? -20.399 18.012  -86.370  1.00 131.52 ? 18  VAL J O   1 
ATOM   10587 C CB  . VAL F 2 18  ? -17.895 18.503  -87.701  1.00 135.73 ? 18  VAL J CB  1 
ATOM   10588 C CG1 . VAL F 2 18  ? -16.381 18.609  -87.515  1.00 129.71 ? 18  VAL J CG1 1 
ATOM   10589 C CG2 . VAL F 2 18  ? -18.257 18.781  -89.153  1.00 127.03 ? 18  VAL J CG2 1 
ATOM   10590 N N   . ASP F 2 19  ? -20.663 16.233  -87.700  1.00 133.22 ? 19  ASP J N   1 
ATOM   10591 C CA  . ASP F 2 19  ? -22.105 16.143  -87.500  1.00 137.19 ? 19  ASP J CA  1 
ATOM   10592 C C   . ASP F 2 19  ? -22.520 14.746  -87.049  1.00 133.59 ? 19  ASP J C   1 
ATOM   10593 O O   . ASP F 2 19  ? -23.578 14.241  -87.432  1.00 140.73 ? 19  ASP J O   1 
ATOM   10594 C CB  . ASP F 2 19  ? -22.874 16.554  -88.757  1.00 136.74 ? 19  ASP J CB  1 
ATOM   10595 C CG  . ASP F 2 19  ? -22.629 15.631  -89.944  1.00 144.13 ? 19  ASP J CG  1 
ATOM   10596 O OD1 . ASP F 2 19  ? -21.641 15.853  -90.673  1.00 141.24 ? 19  ASP J OD1 1 
ATOM   10597 O OD2 . ASP F 2 19  ? -23.432 14.696  -90.159  1.00 141.39 ? 19  ASP J OD2 1 
ATOM   10598 N N   . GLY F 2 20  ? -21.721 14.124  -86.190  1.00 125.27 ? 20  GLY J N   1 
ATOM   10599 C CA  . GLY F 2 20  ? -22.076 12.827  -85.650  1.00 120.25 ? 20  GLY J CA  1 
ATOM   10600 C C   . GLY F 2 20  ? -20.919 12.218  -84.890  1.00 117.66 ? 20  GLY J C   1 
ATOM   10601 O O   . GLY F 2 20  ? -19.804 12.750  -84.863  1.00 125.87 ? 20  GLY J O   1 
ATOM   10602 N N   . TRP F 2 21  ? -21.215 11.080  -84.262  1.00 112.56 ? 21  TRP J N   1 
ATOM   10603 C CA  . TRP F 2 21  ? -20.213 10.292  -83.551  1.00 119.44 ? 21  TRP J CA  1 
ATOM   10604 C C   . TRP F 2 21  ? -19.647 9.183   -84.432  1.00 120.88 ? 21  TRP J C   1 
ATOM   10605 O O   . TRP F 2 21  ? -18.432 9.101   -84.630  1.00 123.06 ? 21  TRP J O   1 
ATOM   10606 C CB  . TRP F 2 21  ? -20.808 9.704   -82.264  1.00 121.85 ? 21  TRP J CB  1 
ATOM   10607 C CG  . TRP F 2 21  ? -20.755 10.640  -81.092  1.00 120.28 ? 21  TRP J CG  1 
ATOM   10608 C CD1 . TRP F 2 21  ? -20.193 11.883  -81.060  1.00 119.65 ? 21  TRP J CD1 1 
ATOM   10609 C CD2 . TRP F 2 21  ? -21.283 10.405  -79.780  1.00 122.51 ? 21  TRP J CD2 1 
ATOM   10610 N NE1 . TRP F 2 21  ? -20.340 12.438  -79.812  1.00 126.29 ? 21  TRP J NE1 1 
ATOM   10611 C CE2 . TRP F 2 21  ? -21.006 11.551  -79.008  1.00 122.16 ? 21  TRP J CE2 1 
ATOM   10612 C CE3 . TRP F 2 21  ? -21.964 9.339   -79.184  1.00 115.81 ? 21  TRP J CE3 1 
ATOM   10613 C CZ2 . TRP F 2 21  ? -21.386 11.661  -77.672  1.00 104.35 ? 21  TRP J CZ2 1 
ATOM   10614 C CZ3 . TRP F 2 21  ? -22.340 9.450   -77.858  1.00 110.24 ? 21  TRP J CZ3 1 
ATOM   10615 C CH2 . TRP F 2 21  ? -22.050 10.602  -77.117  1.00 110.17 ? 21  TRP J CH2 1 
ATOM   10616 N N   . TYR F 2 22  ? -20.512 8.324   -84.962  1.00 121.25 ? 22  TYR J N   1 
ATOM   10617 C CA  . TYR F 2 22  ? -20.127 7.290   -85.909  1.00 127.96 ? 22  TYR J CA  1 
ATOM   10618 C C   . TYR F 2 22  ? -20.627 7.669   -87.297  1.00 129.04 ? 22  TYR J C   1 
ATOM   10619 O O   . TYR F 2 22  ? -21.626 8.379   -87.441  1.00 118.62 ? 22  TYR J O   1 
ATOM   10620 C CB  . TYR F 2 22  ? -20.696 5.927   -85.504  1.00 126.19 ? 22  TYR J CB  1 
ATOM   10621 C CG  . TYR F 2 22  ? -20.753 5.701   -84.010  1.00 127.01 ? 22  TYR J CG  1 
ATOM   10622 C CD1 . TYR F 2 22  ? -19.634 5.275   -83.308  1.00 118.09 ? 22  TYR J CD1 1 
ATOM   10623 C CD2 . TYR F 2 22  ? -21.931 5.909   -83.303  1.00 118.17 ? 22  TYR J CD2 1 
ATOM   10624 C CE1 . TYR F 2 22  ? -19.684 5.066   -81.942  1.00 116.45 ? 22  TYR J CE1 1 
ATOM   10625 C CE2 . TYR F 2 22  ? -21.991 5.702   -81.939  1.00 115.28 ? 22  TYR J CE2 1 
ATOM   10626 C CZ  . TYR F 2 22  ? -20.865 5.282   -81.263  1.00 116.02 ? 22  TYR J CZ  1 
ATOM   10627 O OH  . TYR F 2 22  ? -20.923 5.074   -79.904  1.00 108.35 ? 22  TYR J OH  1 
ATOM   10628 N N   . GLY F 2 23  ? -19.928 7.193   -88.319  1.00 132.03 ? 23  GLY J N   1 
ATOM   10629 C CA  . GLY F 2 23  ? -20.316 7.545   -89.667  1.00 132.61 ? 23  GLY J CA  1 
ATOM   10630 C C   . GLY F 2 23  ? -19.552 6.758   -90.706  1.00 133.02 ? 23  GLY J C   1 
ATOM   10631 O O   . GLY F 2 23  ? -18.882 5.769   -90.401  1.00 124.86 ? 23  GLY J O   1 
ATOM   10632 N N   . TYR F 2 24  ? -19.667 7.220   -91.951  1.00 135.92 ? 24  TYR J N   1 
ATOM   10633 C CA  . TYR F 2 24  ? -19.054 6.568   -93.098  1.00 133.43 ? 24  TYR J CA  1 
ATOM   10634 C C   . TYR F 2 24  ? -18.248 7.574   -93.905  1.00 129.52 ? 24  TYR J C   1 
ATOM   10635 O O   . TYR F 2 24  ? -18.535 8.775   -93.902  1.00 114.75 ? 24  TYR J O   1 
ATOM   10636 C CB  . TYR F 2 24  ? -20.099 5.929   -94.027  1.00 130.41 ? 24  TYR J CB  1 
ATOM   10637 C CG  . TYR F 2 24  ? -21.214 5.179   -93.335  1.00 122.25 ? 24  TYR J CG  1 
ATOM   10638 C CD1 . TYR F 2 24  ? -22.362 5.838   -92.915  1.00 119.78 ? 24  TYR J CD1 1 
ATOM   10639 C CD2 . TYR F 2 24  ? -21.133 3.808   -93.131  1.00 118.99 ? 24  TYR J CD2 1 
ATOM   10640 C CE1 . TYR F 2 24  ? -23.388 5.157   -92.293  1.00 123.14 ? 24  TYR J CE1 1 
ATOM   10641 C CE2 . TYR F 2 24  ? -22.156 3.117   -92.510  1.00 119.50 ? 24  TYR J CE2 1 
ATOM   10642 C CZ  . TYR F 2 24  ? -23.282 3.797   -92.094  1.00 125.15 ? 24  TYR J CZ  1 
ATOM   10643 O OH  . TYR F 2 24  ? -24.307 3.119   -91.477  1.00 122.18 ? 24  TYR J OH  1 
ATOM   10644 N N   . HIS F 2 25  ? -17.236 7.066   -94.605  1.00 139.81 ? 25  HIS J N   1 
ATOM   10645 C CA  . HIS F 2 25  ? -16.494 7.823   -95.605  1.00 144.81 ? 25  HIS J CA  1 
ATOM   10646 C C   . HIS F 2 25  ? -16.538 7.043   -96.911  1.00 143.65 ? 25  HIS J C   1 
ATOM   10647 O O   . HIS F 2 25  ? -16.135 5.875   -96.952  1.00 138.16 ? 25  HIS J O   1 
ATOM   10648 C CB  . HIS F 2 25  ? -15.048 8.063   -95.166  1.00 144.64 ? 25  HIS J CB  1 
ATOM   10649 C CG  . HIS F 2 25  ? -14.203 8.732   -96.205  1.00 145.11 ? 25  HIS J CG  1 
ATOM   10650 N ND1 . HIS F 2 25  ? -14.533 9.947   -96.765  1.00 139.97 ? 25  HIS J ND1 1 
ATOM   10651 C CD2 . HIS F 2 25  ? -13.040 8.354   -96.787  1.00 143.08 ? 25  HIS J CD2 1 
ATOM   10652 C CE1 . HIS F 2 25  ? -13.611 10.289  -97.647  1.00 142.53 ? 25  HIS J CE1 1 
ATOM   10653 N NE2 . HIS F 2 25  ? -12.693 9.339   -97.679  1.00 148.97 ? 25  HIS J NE2 1 
ATOM   10654 N N   . HIS F 2 26  ? -17.020 7.685   -97.970  1.00 145.56 ? 26  HIS J N   1 
ATOM   10655 C CA  . HIS F 2 26  ? -17.216 7.036   -99.257  1.00 149.17 ? 26  HIS J CA  1 
ATOM   10656 C C   . HIS F 2 26  ? -16.248 7.598   -100.290 1.00 154.66 ? 26  HIS J C   1 
ATOM   10657 O O   . HIS F 2 26  ? -15.867 8.771   -100.238 1.00 150.92 ? 26  HIS J O   1 
ATOM   10658 C CB  . HIS F 2 26  ? -18.657 7.207   -99.748  1.00 146.21 ? 26  HIS J CB  1 
ATOM   10659 C CG  . HIS F 2 26  ? -19.029 8.624   -100.052 1.00 148.35 ? 26  HIS J CG  1 
ATOM   10660 N ND1 . HIS F 2 26  ? -19.526 9.485   -99.097  1.00 144.78 ? 26  HIS J ND1 1 
ATOM   10661 C CD2 . HIS F 2 26  ? -18.980 9.331   -101.206 1.00 152.54 ? 26  HIS J CD2 1 
ATOM   10662 C CE1 . HIS F 2 26  ? -19.766 10.661  -99.650  1.00 145.95 ? 26  HIS J CE1 1 
ATOM   10663 N NE2 . HIS F 2 26  ? -19.442 10.594  -100.929 1.00 150.78 ? 26  HIS J NE2 1 
ATOM   10664 N N   . SER F 2 27  ? -15.854 6.742   -101.233 1.00 160.65 ? 27  SER J N   1 
ATOM   10665 C CA  . SER F 2 27  ? -14.903 7.111   -102.282 1.00 160.07 ? 27  SER J CA  1 
ATOM   10666 C C   . SER F 2 27  ? -15.366 6.475   -103.589 1.00 167.18 ? 27  SER J C   1 
ATOM   10667 O O   . SER F 2 27  ? -15.146 5.281   -103.817 1.00 165.42 ? 27  SER J O   1 
ATOM   10668 C CB  . SER F 2 27  ? -13.489 6.670   -101.919 1.00 155.47 ? 27  SER J CB  1 
ATOM   10669 O OG  . SER F 2 27  ? -12.569 7.009   -102.942 1.00 164.17 ? 27  SER J OG  1 
ATOM   10670 N N   . ASN F 2 28  ? -16.010 7.273   -104.440 1.00 168.09 ? 28  ASN J N   1 
ATOM   10671 C CA  . ASN F 2 28  ? -16.431 6.809   -105.757 1.00 167.62 ? 28  ASN J CA  1 
ATOM   10672 C C   . ASN F 2 28  ? -15.974 7.792   -106.828 1.00 168.81 ? 28  ASN J C   1 
ATOM   10673 O O   . ASN F 2 28  ? -15.207 8.716   -106.538 1.00 168.27 ? 28  ASN J O   1 
ATOM   10674 C CB  . ASN F 2 28  ? -17.950 6.617   -105.807 1.00 162.96 ? 28  ASN J CB  1 
ATOM   10675 C CG  . ASN F 2 28  ? -18.713 7.923   -105.675 1.00 155.67 ? 28  ASN J CG  1 
ATOM   10676 O OD1 . ASN F 2 28  ? -18.221 8.890   -105.094 1.00 149.88 ? 28  ASN J OD1 1 
ATOM   10677 N ND2 . ASN F 2 28  ? -19.927 7.953   -106.211 1.00 151.61 ? 28  ASN J ND2 1 
ATOM   10678 N N   . GLU F 2 29  ? -16.433 7.605   -108.066 1.00 166.72 ? 29  GLU J N   1 
ATOM   10679 C CA  . GLU F 2 29  ? -16.054 8.512   -109.142 1.00 170.67 ? 29  GLU J CA  1 
ATOM   10680 C C   . GLU F 2 29  ? -16.802 9.837   -109.093 1.00 170.48 ? 29  GLU J C   1 
ATOM   10681 O O   . GLU F 2 29  ? -16.470 10.744  -109.864 1.00 173.95 ? 29  GLU J O   1 
ATOM   10682 C CB  . GLU F 2 29  ? -16.276 7.850   -110.507 1.00 171.30 ? 29  GLU J CB  1 
ATOM   10683 C CG  . GLU F 2 29  ? -17.730 7.558   -110.846 1.00 171.10 ? 29  GLU J CG  1 
ATOM   10684 C CD  . GLU F 2 29  ? -17.926 7.203   -112.309 1.00 149.93 ? 29  GLU J CD  1 
ATOM   10685 O OE1 . GLU F 2 29  ? -17.190 7.750   -113.159 1.00 138.12 ? 29  GLU J OE1 1 
ATOM   10686 O OE2 . GLU F 2 29  ? -18.811 6.375   -112.611 1.00 128.96 ? 29  GLU J OE2 1 
ATOM   10687 N N   . GLN F 2 30  ? -17.798 9.973   -108.217 1.00 160.34 ? 30  GLN J N   1 
ATOM   10688 C CA  . GLN F 2 30  ? -18.545 11.216  -108.084 1.00 153.72 ? 30  GLN J CA  1 
ATOM   10689 C C   . GLN F 2 30  ? -17.985 12.142  -107.011 1.00 158.57 ? 30  GLN J C   1 
ATOM   10690 O O   . GLN F 2 30  ? -18.431 13.291  -106.916 1.00 147.04 ? 30  GLN J O   1 
ATOM   10691 C CB  . GLN F 2 30  ? -20.017 10.915  -107.781 1.00 148.74 ? 30  GLN J CB  1 
ATOM   10692 C CG  . GLN F 2 30  ? -20.688 10.023  -108.813 1.00 149.70 ? 30  GLN J CG  1 
ATOM   10693 C CD  . GLN F 2 30  ? -22.118 9.677   -108.445 1.00 150.54 ? 30  GLN J CD  1 
ATOM   10694 O OE1 . GLN F 2 30  ? -22.465 8.506   -108.292 1.00 150.67 ? 30  GLN J OE1 1 
ATOM   10695 N NE2 . GLN F 2 30  ? -22.957 10.697  -108.307 1.00 147.10 ? 30  GLN J NE2 1 
ATOM   10696 N N   . GLY F 2 31  ? -17.030 11.683  -106.210 1.00 162.94 ? 31  GLY J N   1 
ATOM   10697 C CA  . GLY F 2 31  ? -16.402 12.515  -105.209 1.00 160.09 ? 31  GLY J CA  1 
ATOM   10698 C C   . GLY F 2 31  ? -16.254 11.769  -103.901 1.00 157.42 ? 31  GLY J C   1 
ATOM   10699 O O   . GLY F 2 31  ? -16.379 10.547  -103.847 1.00 150.35 ? 31  GLY J O   1 
ATOM   10700 N N   . SER F 2 32  ? -15.980 12.530  -102.842 1.00 149.71 ? 32  SER J N   1 
ATOM   10701 C CA  . SER F 2 32  ? -15.812 11.981  -101.505 1.00 145.85 ? 32  SER J CA  1 
ATOM   10702 C C   . SER F 2 32  ? -16.535 12.874  -100.507 1.00 146.76 ? 32  SER J C   1 
ATOM   10703 O O   . SER F 2 32  ? -16.826 14.041  -100.783 1.00 134.15 ? 32  SER J O   1 
ATOM   10704 C CB  . SER F 2 32  ? -14.331 11.853  -101.125 1.00 141.26 ? 32  SER J CB  1 
ATOM   10705 O OG  . SER F 2 32  ? -13.644 10.995  -102.019 1.00 148.09 ? 32  SER J OG  1 
ATOM   10706 N N   . GLY F 2 33  ? -16.824 12.310  -99.341  1.00 149.50 ? 33  GLY J N   1 
ATOM   10707 C CA  . GLY F 2 33  ? -17.497 13.067  -98.301  1.00 140.93 ? 33  GLY J CA  1 
ATOM   10708 C C   . GLY F 2 33  ? -17.655 12.231  -97.051  1.00 131.85 ? 33  GLY J C   1 
ATOM   10709 O O   . GLY F 2 33  ? -17.317 11.043  -97.017  1.00 129.16 ? 33  GLY J O   1 
ATOM   10710 N N   . TYR F 2 34  ? -18.178 12.878  -96.013  1.00 132.86 ? 34  TYR J N   1 
ATOM   10711 C CA  . TYR F 2 34  ? -18.437 12.241  -94.730  1.00 131.14 ? 34  TYR J CA  1 
ATOM   10712 C C   . TYR F 2 34  ? -19.939 12.168  -94.495  1.00 128.64 ? 34  TYR J C   1 
ATOM   10713 O O   . TYR F 2 34  ? -20.648 13.166  -94.663  1.00 120.11 ? 34  TYR J O   1 
ATOM   10714 C CB  . TYR F 2 34  ? -17.765 13.005  -93.585  1.00 121.20 ? 34  TYR J CB  1 
ATOM   10715 C CG  . TYR F 2 34  ? -16.258 13.076  -93.684  1.00 125.99 ? 34  TYR J CG  1 
ATOM   10716 C CD1 . TYR F 2 34  ? -15.480 11.929  -93.580  1.00 125.55 ? 34  TYR J CD1 1 
ATOM   10717 C CD2 . TYR F 2 34  ? -15.611 14.292  -93.866  1.00 118.91 ? 34  TYR J CD2 1 
ATOM   10718 C CE1 . TYR F 2 34  ? -14.101 11.991  -93.666  1.00 126.16 ? 34  TYR J CE1 1 
ATOM   10719 C CE2 . TYR F 2 34  ? -14.233 14.363  -93.952  1.00 111.14 ? 34  TYR J CE2 1 
ATOM   10720 C CZ  . TYR F 2 34  ? -13.483 13.210  -93.851  1.00 121.36 ? 34  TYR J CZ  1 
ATOM   10721 O OH  . TYR F 2 34  ? -12.111 13.276  -93.936  1.00 108.43 ? 34  TYR J OH  1 
ATOM   10722 N N   . ALA F 2 35  ? -20.417 10.988  -94.110  1.00 127.35 ? 35  ALA J N   1 
ATOM   10723 C CA  . ALA F 2 35  ? -21.821 10.764  -93.803  1.00 133.00 ? 35  ALA J CA  1 
ATOM   10724 C C   . ALA F 2 35  ? -21.948 10.213  -92.390  1.00 136.87 ? 35  ALA J C   1 
ATOM   10725 O O   . ALA F 2 35  ? -21.095 9.452   -91.928  1.00 133.67 ? 35  ALA J O   1 
ATOM   10726 C CB  . ALA F 2 35  ? -22.464 9.797   -94.799  1.00 134.04 ? 35  ALA J CB  1 
ATOM   10727 N N   . ALA F 2 36  ? -23.022 10.602  -91.709  1.00 139.12 ? 36  ALA J N   1 
ATOM   10728 C CA  . ALA F 2 36  ? -23.242 10.246  -90.314  1.00 134.59 ? 36  ALA J CA  1 
ATOM   10729 C C   . ALA F 2 36  ? -24.369 9.229   -90.205  1.00 128.99 ? 36  ALA J C   1 
ATOM   10730 O O   . ALA F 2 36  ? -25.439 9.414   -90.795  1.00 132.11 ? 36  ALA J O   1 
ATOM   10731 C CB  . ALA F 2 36  ? -23.572 11.486  -89.479  1.00 123.68 ? 36  ALA J CB  1 
ATOM   10732 N N   . ASP F 2 37  ? -24.124 8.157   -89.452  1.00 122.57 ? 37  ASP J N   1 
ATOM   10733 C CA  . ASP F 2 37  ? -25.166 7.187   -89.123  1.00 117.60 ? 37  ASP J CA  1 
ATOM   10734 C C   . ASP F 2 37  ? -25.993 7.789   -87.996  1.00 113.24 ? 37  ASP J C   1 
ATOM   10735 O O   . ASP F 2 37  ? -25.694 7.618   -86.813  1.00 115.62 ? 37  ASP J O   1 
ATOM   10736 C CB  . ASP F 2 37  ? -24.562 5.843   -88.733  1.00 117.24 ? 37  ASP J CB  1 
ATOM   10737 C CG  . ASP F 2 37  ? -25.606 4.742   -88.608  1.00 112.74 ? 37  ASP J CG  1 
ATOM   10738 O OD1 . ASP F 2 37  ? -26.695 4.993   -88.050  1.00 112.94 ? 37  ASP J OD1 1 
ATOM   10739 O OD2 . ASP F 2 37  ? -25.334 3.615   -89.068  1.00 109.14 ? 37  ASP J OD2 1 
ATOM   10740 N N   . LYS F 2 38  ? -27.048 8.513   -88.378  1.00 119.36 ? 38  LYS J N   1 
ATOM   10741 C CA  . LYS F 2 38  ? -27.896 9.179   -87.396  1.00 111.46 ? 38  LYS J CA  1 
ATOM   10742 C C   . LYS F 2 38  ? -28.548 8.185   -86.447  1.00 115.59 ? 38  LYS J C   1 
ATOM   10743 O O   . LYS F 2 38  ? -28.731 8.488   -85.263  1.00 109.61 ? 38  LYS J O   1 
ATOM   10744 C CB  . LYS F 2 38  ? -28.965 10.020  -88.096  1.00 107.34 ? 38  LYS J CB  1 
ATOM   10745 C CG  . LYS F 2 38  ? -29.790 9.271   -89.143  1.00 110.64 ? 38  LYS J CG  1 
ATOM   10746 C CD  . LYS F 2 38  ? -29.151 9.339   -90.527  1.00 107.56 ? 38  LYS J CD  1 
ATOM   10747 C CE  . LYS F 2 38  ? -29.977 8.595   -91.564  1.00 107.42 ? 38  LYS J CE  1 
ATOM   10748 N NZ  . LYS F 2 38  ? -29.248 8.447   -92.855  1.00 102.37 ? 38  LYS J NZ  1 
ATOM   10749 N N   . GLU F 2 39  ? -28.910 7.000   -86.940  1.00 114.57 ? 39  GLU J N   1 
ATOM   10750 C CA  . GLU F 2 39  ? -29.456 5.990   -86.044  1.00 107.79 ? 39  GLU J CA  1 
ATOM   10751 C C   . GLU F 2 39  ? -28.416 5.537   -85.031  1.00 107.99 ? 39  GLU J C   1 
ATOM   10752 O O   . GLU F 2 39  ? -28.713 5.450   -83.837  1.00 110.39 ? 39  GLU J O   1 
ATOM   10753 C CB  . GLU F 2 39  ? -29.982 4.800   -86.844  1.00 107.78 ? 39  GLU J CB  1 
ATOM   10754 C CG  . GLU F 2 39  ? -30.836 3.836   -86.031  1.00 112.18 ? 39  GLU J CG  1 
ATOM   10755 C CD  . GLU F 2 39  ? -30.507 2.380   -86.306  1.00 116.35 ? 39  GLU J CD  1 
ATOM   10756 O OE1 . GLU F 2 39  ? -29.305 2.054   -86.394  1.00 116.45 ? 39  GLU J OE1 1 
ATOM   10757 O OE2 . GLU F 2 39  ? -31.446 1.565   -86.437  1.00 103.40 ? 39  GLU J OE2 1 
ATOM   10758 N N   . SER F 2 40  ? -27.183 5.280   -85.475  1.00 110.77 ? 40  SER J N   1 
ATOM   10759 C CA  . SER F 2 40  ? -26.189 4.715   -84.562  1.00 105.41 ? 40  SER J CA  1 
ATOM   10760 C C   . SER F 2 40  ? -25.785 5.704   -83.475  1.00 106.13 ? 40  SER J C   1 
ATOM   10761 O O   . SER F 2 40  ? -25.634 5.322   -82.308  1.00 98.84  ? 40  SER J O   1 
ATOM   10762 C CB  . SER F 2 40  ? -24.958 4.241   -85.331  1.00 107.68 ? 40  SER J CB  1 
ATOM   10763 O OG  . SER F 2 40  ? -24.046 3.608   -84.451  1.00 112.96 ? 40  SER J OG  1 
ATOM   10764 N N   . THR F 2 41  ? -25.600 6.972   -83.835  1.00 103.01 ? 41  THR J N   1 
ATOM   10765 C CA  . THR F 2 41  ? -25.184 7.965   -82.852  1.00 102.41 ? 41  THR J CA  1 
ATOM   10766 C C   . THR F 2 41  ? -26.307 8.308   -81.883  1.00 105.73 ? 41  THR J C   1 
ATOM   10767 O O   . THR F 2 41  ? -26.042 8.607   -80.713  1.00 107.90 ? 41  THR J O   1 
ATOM   10768 C CB  . THR F 2 41  ? -24.696 9.226   -83.559  1.00 106.37 ? 41  THR J CB  1 
ATOM   10769 O OG1 . THR F 2 41  ? -25.809 9.883   -84.177  1.00 107.53 ? 41  THR J OG1 1 
ATOM   10770 C CG2 . THR F 2 41  ? -23.685 8.863   -84.626  1.00 108.25 ? 41  THR J CG2 1 
ATOM   10771 N N   . GLN F 2 42  ? -27.558 8.282   -82.348  1.00 101.75 ? 42  GLN J N   1 
ATOM   10772 C CA  . GLN F 2 42  ? -28.676 8.614   -81.471  1.00 105.43 ? 42  GLN J CA  1 
ATOM   10773 C C   . GLN F 2 42  ? -28.830 7.592   -80.347  1.00 103.93 ? 42  GLN J C   1 
ATOM   10774 O O   . GLN F 2 42  ? -29.117 7.964   -79.204  1.00 108.65 ? 42  GLN J O   1 
ATOM   10775 C CB  . GLN F 2 42  ? -29.966 8.733   -82.282  1.00 107.95 ? 42  GLN J CB  1 
ATOM   10776 C CG  . GLN F 2 42  ? -31.112 9.395   -81.529  1.00 104.74 ? 42  GLN J CG  1 
ATOM   10777 C CD  . GLN F 2 42  ? -30.828 10.846  -81.177  1.00 107.12 ? 42  GLN J CD  1 
ATOM   10778 O OE1 . GLN F 2 42  ? -29.982 11.494  -81.794  1.00 107.90 ? 42  GLN J OE1 1 
ATOM   10779 N NE2 . GLN F 2 42  ? -31.538 11.361  -80.180  1.00 112.05 ? 42  GLN J NE2 1 
ATOM   10780 N N   . LYS F 2 43  ? -28.645 6.303   -80.647  1.00 101.82 ? 43  LYS J N   1 
ATOM   10781 C CA  . LYS F 2 43  ? -28.674 5.291   -79.593  1.00 105.93 ? 43  LYS J CA  1 
ATOM   10782 C C   . LYS F 2 43  ? -27.546 5.515   -78.595  1.00 101.20 ? 43  LYS J C   1 
ATOM   10783 O O   . LYS F 2 43  ? -27.725 5.336   -77.384  1.00 102.81 ? 43  LYS J O   1 
ATOM   10784 C CB  . LYS F 2 43  ? -28.572 3.889   -80.200  1.00 105.21 ? 43  LYS J CB  1 
ATOM   10785 C CG  . LYS F 2 43  ? -29.384 3.712   -81.466  1.00 109.54 ? 43  LYS J CG  1 
ATOM   10786 C CD  . LYS F 2 43  ? -29.266 2.327   -82.126  1.00 114.19 ? 43  LYS J CD  1 
ATOM   10787 C CE  . LYS F 2 43  ? -27.878 1.671   -81.960  1.00 117.70 ? 43  LYS J CE  1 
ATOM   10788 N NZ  . LYS F 2 43  ? -26.728 2.489   -82.436  1.00 116.05 ? 43  LYS J NZ  1 
ATOM   10789 N N   . ALA F 2 44  ? -26.369 5.894   -79.091  1.00 95.00  ? 44  ALA J N   1 
ATOM   10790 C CA  . ALA F 2 44  ? -25.240 6.139   -78.204  1.00 96.40  ? 44  ALA J CA  1 
ATOM   10791 C C   . ALA F 2 44  ? -25.426 7.426   -77.412  1.00 102.16 ? 44  ALA J C   1 
ATOM   10792 O O   . ALA F 2 44  ? -25.078 7.486   -76.228  1.00 98.02  ? 44  ALA J O   1 
ATOM   10793 C CB  . ALA F 2 44  ? -23.942 6.179   -79.008  1.00 100.16 ? 44  ALA J CB  1 
ATOM   10794 N N   . ILE F 2 45  ? -25.972 8.467   -78.048  1.00 104.08 ? 45  ILE J N   1 
ATOM   10795 C CA  . ILE F 2 45  ? -26.169 9.741   -77.357  1.00 99.51  ? 45  ILE J CA  1 
ATOM   10796 C C   . ILE F 2 45  ? -27.143 9.572   -76.199  1.00 104.71 ? 45  ILE J C   1 
ATOM   10797 O O   . ILE F 2 45  ? -26.893 10.035  -75.079  1.00 102.61 ? 45  ILE J O   1 
ATOM   10798 C CB  . ILE F 2 45  ? -26.642 10.825  -78.344  1.00 102.29 ? 45  ILE J CB  1 
ATOM   10799 C CG1 . ILE F 2 45  ? -25.443 11.478  -79.036  1.00 103.71 ? 45  ILE J CG1 1 
ATOM   10800 C CG2 . ILE F 2 45  ? -27.492 11.874  -77.634  1.00 91.10  ? 45  ILE J CG2 1 
ATOM   10801 C CD1 . ILE F 2 45  ? -25.801 12.701  -79.853  1.00 94.44  ? 45  ILE J CD1 1 
ATOM   10802 N N   . ASP F 2 46  ? -28.267 8.897   -76.447  1.00 104.93 ? 46  ASP J N   1 
ATOM   10803 C CA  . ASP F 2 46  ? -29.235 8.671   -75.381  1.00 105.10 ? 46  ASP J CA  1 
ATOM   10804 C C   . ASP F 2 46  ? -28.700 7.705   -74.332  1.00 102.80 ? 46  ASP J C   1 
ATOM   10805 O O   . ASP F 2 46  ? -29.076 7.797   -73.159  1.00 92.87  ? 46  ASP J O   1 
ATOM   10806 C CB  . ASP F 2 46  ? -30.550 8.156   -75.966  1.00 103.31 ? 46  ASP J CB  1 
ATOM   10807 C CG  . ASP F 2 46  ? -31.291 9.218   -76.758  1.00 110.52 ? 46  ASP J CG  1 
ATOM   10808 O OD1 . ASP F 2 46  ? -30.716 9.748   -77.732  1.00 105.87 ? 46  ASP J OD1 1 
ATOM   10809 O OD2 . ASP F 2 46  ? -32.451 9.523   -76.406  1.00 115.77 ? 46  ASP J OD2 1 
ATOM   10810 N N   . GLY F 2 47  ? -27.827 6.777   -74.732  1.00 105.76 ? 47  GLY J N   1 
ATOM   10811 C CA  . GLY F 2 47  ? -27.288 5.821   -73.778  1.00 96.77  ? 47  GLY J CA  1 
ATOM   10812 C C   . GLY F 2 47  ? -26.398 6.462   -72.729  1.00 101.04 ? 47  GLY J C   1 
ATOM   10813 O O   . GLY F 2 47  ? -26.511 6.157   -71.538  1.00 102.36 ? 47  GLY J O   1 
ATOM   10814 N N   . VAL F 2 48  ? -25.502 7.357   -73.150  1.00 94.60  ? 48  VAL J N   1 
ATOM   10815 C CA  . VAL F 2 48  ? -24.602 7.990   -72.190  1.00 97.31  ? 48  VAL J CA  1 
ATOM   10816 C C   . VAL F 2 48  ? -25.292 9.139   -71.464  1.00 93.99  ? 48  VAL J C   1 
ATOM   10817 O O   . VAL F 2 48  ? -24.959 9.435   -70.310  1.00 92.09  ? 48  VAL J O   1 
ATOM   10818 C CB  . VAL F 2 48  ? -23.308 8.456   -72.880  1.00 90.26  ? 48  VAL J CB  1 
ATOM   10819 C CG1 . VAL F 2 48  ? -22.482 7.256   -73.322  1.00 79.81  ? 48  VAL J CG1 1 
ATOM   10820 C CG2 . VAL F 2 48  ? -23.623 9.357   -74.063  1.00 97.75  ? 48  VAL J CG2 1 
ATOM   10821 N N   . THR F 2 49  ? -26.247 9.810   -72.113  1.00 94.67  ? 49  THR J N   1 
ATOM   10822 C CA  . THR F 2 49  ? -27.044 10.812  -71.412  1.00 88.96  ? 49  THR J CA  1 
ATOM   10823 C C   . THR F 2 49  ? -27.864 10.170  -70.300  1.00 96.86  ? 49  THR J C   1 
ATOM   10824 O O   . THR F 2 49  ? -27.960 10.714  -69.193  1.00 93.26  ? 49  THR J O   1 
ATOM   10825 C CB  . THR F 2 49  ? -27.952 11.549  -72.399  1.00 94.38  ? 49  THR J CB  1 
ATOM   10826 O OG1 . THR F 2 49  ? -27.163 12.423  -73.217  1.00 99.29  ? 49  THR J OG1 1 
ATOM   10827 C CG2 . THR F 2 49  ? -29.006 12.364  -71.662  1.00 70.58  ? 49  THR J CG2 1 
ATOM   10828 N N   . ASN F 2 50  ? -28.453 9.004   -70.573  1.00 98.57  ? 50  ASN J N   1 
ATOM   10829 C CA  . ASN F 2 50  ? -29.214 8.300   -69.547  1.00 83.51  ? 50  ASN J CA  1 
ATOM   10830 C C   . ASN F 2 50  ? -28.304 7.804   -68.429  1.00 83.90  ? 50  ASN J C   1 
ATOM   10831 O O   . ASN F 2 50  ? -28.687 7.833   -67.253  1.00 82.71  ? 50  ASN J O   1 
ATOM   10832 C CB  . ASN F 2 50  ? -29.988 7.141   -70.174  1.00 77.44  ? 50  ASN J CB  1 
ATOM   10833 C CG  . ASN F 2 50  ? -31.349 6.941   -69.541  1.00 100.08 ? 50  ASN J CG  1 
ATOM   10834 O OD1 . ASN F 2 50  ? -31.597 5.935   -68.877  1.00 97.92  ? 50  ASN J OD1 1 
ATOM   10835 N ND2 . ASN F 2 50  ? -32.240 7.908   -69.738  1.00 102.71 ? 50  ASN J ND2 1 
ATOM   10836 N N   . LYS F 2 51  ? -27.099 7.338   -68.774  1.00 83.15  ? 51  LYS J N   1 
ATOM   10837 C CA  . LYS F 2 51  ? -26.157 6.898   -67.748  1.00 75.52  ? 51  LYS J CA  1 
ATOM   10838 C C   . LYS F 2 51  ? -25.751 8.049   -66.838  1.00 80.02  ? 51  LYS J C   1 
ATOM   10839 O O   . LYS F 2 51  ? -25.702 7.893   -65.612  1.00 80.85  ? 51  LYS J O   1 
ATOM   10840 C CB  . LYS F 2 51  ? -24.920 6.272   -68.394  1.00 85.29  ? 51  LYS J CB  1 
ATOM   10841 C CG  . LYS F 2 51  ? -23.778 6.054   -67.413  1.00 79.34  ? 51  LYS J CG  1 
ATOM   10842 C CD  . LYS F 2 51  ? -22.480 5.697   -68.116  1.00 83.99  ? 51  LYS J CD  1 
ATOM   10843 C CE  . LYS F 2 51  ? -22.534 4.297   -68.700  1.00 91.65  ? 51  LYS J CE  1 
ATOM   10844 N NZ  . LYS F 2 51  ? -21.191 3.838   -69.165  1.00 91.95  ? 51  LYS J NZ  1 
ATOM   10845 N N   . VAL F 2 52  ? -25.458 9.214   -67.419  1.00 80.64  ? 52  VAL J N   1 
ATOM   10846 C CA  . VAL F 2 52  ? -25.103 10.382  -66.618  1.00 67.62  ? 52  VAL J CA  1 
ATOM   10847 C C   . VAL F 2 52  ? -26.252 10.765  -65.696  1.00 80.13  ? 52  VAL J C   1 
ATOM   10848 O O   . VAL F 2 52  ? -26.049 11.037  -64.506  1.00 79.62  ? 52  VAL J O   1 
ATOM   10849 C CB  . VAL F 2 52  ? -24.695 11.551  -67.534  1.00 83.16  ? 52  VAL J CB  1 
ATOM   10850 C CG1 . VAL F 2 52  ? -24.909 12.884  -66.834  1.00 84.05  ? 52  VAL J CG1 1 
ATOM   10851 C CG2 . VAL F 2 52  ? -23.247 11.405  -67.971  1.00 88.32  ? 52  VAL J CG2 1 
ATOM   10852 N N   . ASN F 2 53  ? -27.477 10.781  -66.225  1.00 76.34  ? 53  ASN J N   1 
ATOM   10853 C CA  . ASN F 2 53  ? -28.618 11.206  -65.423  1.00 80.23  ? 53  ASN J CA  1 
ATOM   10854 C C   . ASN F 2 53  ? -28.980 10.180  -64.357  1.00 82.63  ? 53  ASN J C   1 
ATOM   10855 O O   . ASN F 2 53  ? -29.525 10.548  -63.312  1.00 85.66  ? 53  ASN J O   1 
ATOM   10856 C CB  . ASN F 2 53  ? -29.815 11.487  -66.329  1.00 73.53  ? 53  ASN J CB  1 
ATOM   10857 C CG  . ASN F 2 53  ? -29.594 12.694  -67.221  1.00 84.70  ? 53  ASN J CG  1 
ATOM   10858 O OD1 . ASN F 2 53  ? -28.960 13.670  -66.817  1.00 81.18  ? 53  ASN J OD1 1 
ATOM   10859 N ND2 . ASN F 2 53  ? -30.112 12.632  -68.441  1.00 88.76  ? 53  ASN J ND2 1 
ATOM   10860 N N   . SER F 2 54  ? -28.694 8.898   -64.595  1.00 79.09  ? 54  SER J N   1 
ATOM   10861 C CA  . SER F 2 54  ? -28.979 7.886   -63.581  1.00 75.79  ? 54  SER J CA  1 
ATOM   10862 C C   . SER F 2 54  ? -28.032 8.011   -62.392  1.00 88.70  ? 54  SER J C   1 
ATOM   10863 O O   . SER F 2 54  ? -28.449 7.852   -61.239  1.00 88.52  ? 54  SER J O   1 
ATOM   10864 C CB  . SER F 2 54  ? -28.897 6.489   -64.193  1.00 67.20  ? 54  SER J CB  1 
ATOM   10865 O OG  . SER F 2 54  ? -29.910 6.303   -65.165  1.00 86.63  ? 54  SER J OG  1 
ATOM   10866 N N   . ILE F 2 55  ? -26.755 8.293   -62.654  1.00 82.09  ? 55  ILE J N   1 
ATOM   10867 C CA  . ILE F 2 55  ? -25.801 8.506   -61.571  1.00 73.68  ? 55  ILE J CA  1 
ATOM   10868 C C   . ILE F 2 55  ? -26.162 9.758   -60.779  1.00 77.74  ? 55  ILE J C   1 
ATOM   10869 O O   . ILE F 2 55  ? -26.034 9.792   -59.549  1.00 81.46  ? 55  ILE J O   1 
ATOM   10870 C CB  . ILE F 2 55  ? -24.370 8.567   -62.141  1.00 62.77  ? 55  ILE J CB  1 
ATOM   10871 C CG1 . ILE F 2 55  ? -23.877 7.154   -62.464  1.00 61.11  ? 55  ILE J CG1 1 
ATOM   10872 C CG2 . ILE F 2 55  ? -23.420 9.275   -61.181  1.00 74.81  ? 55  ILE J CG2 1 
ATOM   10873 C CD1 . ILE F 2 55  ? -22.667 7.115   -63.371  1.00 82.69  ? 55  ILE J CD1 1 
ATOM   10874 N N   . ILE F 2 56  ? -26.632 10.800  -61.466  1.00 75.42  ? 56  ILE J N   1 
ATOM   10875 C CA  . ILE F 2 56  ? -27.017 12.034  -60.787  1.00 75.91  ? 56  ILE J CA  1 
ATOM   10876 C C   . ILE F 2 56  ? -28.303 11.839  -59.989  1.00 82.48  ? 56  ILE J C   1 
ATOM   10877 O O   . ILE F 2 56  ? -28.380 12.202  -58.809  1.00 77.52  ? 56  ILE J O   1 
ATOM   10878 C CB  . ILE F 2 56  ? -27.158 13.180  -61.806  1.00 82.76  ? 56  ILE J CB  1 
ATOM   10879 C CG1 . ILE F 2 56  ? -25.803 13.825  -62.085  1.00 74.62  ? 56  ILE J CG1 1 
ATOM   10880 C CG2 . ILE F 2 56  ? -28.160 14.223  -61.319  1.00 71.53  ? 56  ILE J CG2 1 
ATOM   10881 C CD1 . ILE F 2 56  ? -25.887 14.986  -63.042  1.00 69.00  ? 56  ILE J CD1 1 
ATOM   10882 N N   . ASP F 2 57  ? -29.326 11.259  -60.615  1.00 70.66  ? 57  ASP J N   1 
ATOM   10883 C CA  . ASP F 2 57  ? -30.679 11.322  -60.071  1.00 82.69  ? 57  ASP J CA  1 
ATOM   10884 C C   . ASP F 2 57  ? -30.976 10.261  -59.021  1.00 87.52  ? 57  ASP J C   1 
ATOM   10885 O O   . ASP F 2 57  ? -31.817 10.498  -58.146  1.00 77.34  ? 57  ASP J O   1 
ATOM   10886 C CB  . ASP F 2 57  ? -31.706 11.214  -61.202  1.00 90.00  ? 57  ASP J CB  1 
ATOM   10887 C CG  . ASP F 2 57  ? -31.688 12.421  -62.122  1.00 91.80  ? 57  ASP J CG  1 
ATOM   10888 O OD1 . ASP F 2 57  ? -31.501 13.549  -61.616  1.00 96.15  ? 57  ASP J OD1 1 
ATOM   10889 O OD2 . ASP F 2 57  ? -31.856 12.244  -63.348  1.00 96.80  ? 57  ASP J OD2 1 
ATOM   10890 N N   . LYS F 2 58  ? -30.311 9.105   -59.072  1.00 75.18  ? 58  LYS J N   1 
ATOM   10891 C CA  . LYS F 2 58  ? -30.560 8.079   -58.067  1.00 66.29  ? 58  LYS J CA  1 
ATOM   10892 C C   . LYS F 2 58  ? -30.034 8.460   -56.689  1.00 80.12  ? 58  LYS J C   1 
ATOM   10893 O O   . LYS F 2 58  ? -30.356 7.775   -55.713  1.00 81.97  ? 58  LYS J O   1 
ATOM   10894 C CB  . LYS F 2 58  ? -29.953 6.743   -58.507  1.00 61.90  ? 58  LYS J CB  1 
ATOM   10895 C CG  . LYS F 2 58  ? -30.746 6.037   -59.595  1.00 71.63  ? 58  LYS J CG  1 
ATOM   10896 C CD  . LYS F 2 58  ? -32.225 5.986   -59.238  1.00 80.99  ? 58  LYS J CD  1 
ATOM   10897 C CE  . LYS F 2 58  ? -33.043 5.266   -60.299  1.00 72.19  ? 58  LYS J CE  1 
ATOM   10898 N NZ  . LYS F 2 58  ? -32.796 3.798   -60.298  1.00 88.65  ? 58  LYS J NZ  1 
ATOM   10899 N N   . MET F 2 59  ? -29.245 9.528   -56.585  1.00 78.37  ? 59  MET J N   1 
ATOM   10900 C CA  . MET F 2 59  ? -28.724 9.964   -55.296  1.00 60.70  ? 59  MET J CA  1 
ATOM   10901 C C   . MET F 2 59  ? -29.836 10.595  -54.469  1.00 69.08  ? 59  MET J C   1 
ATOM   10902 O O   . MET F 2 59  ? -30.453 11.578  -54.890  1.00 74.52  ? 59  MET J O   1 
ATOM   10903 C CB  . MET F 2 59  ? -27.581 10.955  -55.496  1.00 70.57  ? 59  MET J CB  1 
ATOM   10904 C CG  . MET F 2 59  ? -27.125 11.634  -54.215  1.00 65.88  ? 59  MET J CG  1 
ATOM   10905 S SD  . MET F 2 59  ? -26.432 10.476  -53.020  1.00 67.48  ? 59  MET J SD  1 
ATOM   10906 C CE  . MET F 2 59  ? -24.940 9.969   -53.872  1.00 71.65  ? 59  MET J CE  1 
ATOM   10907 N N   . ASN F 2 60  ? -30.083 10.034  -53.289  1.00 74.49  ? 60  ASN J N   1 
ATOM   10908 C CA  . ASN F 2 60  ? -31.092 10.553  -52.378  1.00 74.50  ? 60  ASN J CA  1 
ATOM   10909 C C   . ASN F 2 60  ? -30.455 11.561  -51.430  1.00 75.09  ? 60  ASN J C   1 
ATOM   10910 O O   . ASN F 2 60  ? -29.468 11.250  -50.755  1.00 79.62  ? 60  ASN J O   1 
ATOM   10911 C CB  . ASN F 2 60  ? -31.745 9.415   -51.592  1.00 70.07  ? 60  ASN J CB  1 
ATOM   10912 C CG  . ASN F 2 60  ? -32.825 9.903   -50.647  1.00 77.98  ? 60  ASN J CG  1 
ATOM   10913 O OD1 . ASN F 2 60  ? -33.924 10.261  -51.072  1.00 83.10  ? 60  ASN J OD1 1 
ATOM   10914 N ND2 . ASN F 2 60  ? -32.519 9.912   -49.354  1.00 67.65  ? 60  ASN J ND2 1 
ATOM   10915 N N   . THR F 2 61  ? -31.016 12.766  -51.390  1.00 59.34  ? 61  THR J N   1 
ATOM   10916 C CA  . THR F 2 61  ? -30.522 13.840  -50.542  1.00 71.01  ? 61  THR J CA  1 
ATOM   10917 C C   . THR F 2 61  ? -31.606 14.248  -49.556  1.00 69.73  ? 61  THR J C   1 
ATOM   10918 O O   . THR F 2 61  ? -32.785 14.339  -49.916  1.00 66.76  ? 61  THR J O   1 
ATOM   10919 C CB  . THR F 2 61  ? -30.093 15.060  -51.367  1.00 72.97  ? 61  THR J CB  1 
ATOM   10920 O OG1 . THR F 2 61  ? -31.223 15.913  -51.582  1.00 82.14  ? 61  THR J OG1 1 
ATOM   10921 C CG2 . THR F 2 61  ? -29.535 14.627  -52.715  1.00 62.30  ? 61  THR J CG2 1 
ATOM   10922 N N   . GLN F 2 62  ? -31.204 14.492  -48.313  1.00 67.24  ? 62  GLN J N   1 
ATOM   10923 C CA  . GLN F 2 62  ? -32.114 14.934  -47.270  1.00 66.03  ? 62  GLN J CA  1 
ATOM   10924 C C   . GLN F 2 62  ? -31.567 16.198  -46.629  1.00 60.19  ? 62  GLN J C   1 
ATOM   10925 O O   . GLN F 2 62  ? -30.369 16.485  -46.694  1.00 67.01  ? 62  GLN J O   1 
ATOM   10926 C CB  . GLN F 2 62  ? -32.317 13.865  -46.189  1.00 66.49  ? 62  GLN J CB  1 
ATOM   10927 C CG  . GLN F 2 62  ? -32.361 12.442  -46.706  1.00 80.65  ? 62  GLN J CG  1 
ATOM   10928 C CD  . GLN F 2 62  ? -32.943 11.486  -45.689  1.00 68.34  ? 62  GLN J CD  1 
ATOM   10929 O OE1 . GLN F 2 62  ? -32.529 10.332  -45.597  1.00 66.28  ? 62  GLN J OE1 1 
ATOM   10930 N NE2 . GLN F 2 62  ? -33.914 11.964  -44.919  1.00 68.80  ? 62  GLN J NE2 1 
ATOM   10931 N N   . PHE F 2 63  ? -32.464 16.960  -46.012  1.00 50.48  ? 63  PHE J N   1 
ATOM   10932 C CA  . PHE F 2 63  ? -32.034 18.100  -45.218  1.00 62.75  ? 63  PHE J CA  1 
ATOM   10933 C C   . PHE F 2 63  ? -31.230 17.615  -44.019  1.00 66.05  ? 63  PHE J C   1 
ATOM   10934 O O   . PHE F 2 63  ? -31.688 16.761  -43.254  1.00 63.83  ? 63  PHE J O   1 
ATOM   10935 C CB  . PHE F 2 63  ? -33.238 18.918  -44.750  1.00 49.98  ? 63  PHE J CB  1 
ATOM   10936 C CG  . PHE F 2 63  ? -32.868 20.127  -43.931  1.00 67.87  ? 63  PHE J CG  1 
ATOM   10937 C CD1 . PHE F 2 63  ? -32.700 20.031  -42.557  1.00 63.11  ? 63  PHE J CD1 1 
ATOM   10938 C CD2 . PHE F 2 63  ? -32.688 21.358  -44.536  1.00 56.06  ? 63  PHE J CD2 1 
ATOM   10939 C CE1 . PHE F 2 63  ? -32.356 21.139  -41.805  1.00 62.96  ? 63  PHE J CE1 1 
ATOM   10940 C CE2 . PHE F 2 63  ? -32.344 22.471  -43.790  1.00 73.88  ? 63  PHE J CE2 1 
ATOM   10941 C CZ  . PHE F 2 63  ? -32.179 22.361  -42.422  1.00 68.53  ? 63  PHE J CZ  1 
ATOM   10942 N N   . GLU F 2 64  ? -30.024 18.154  -43.866  1.00 58.61  ? 64  GLU J N   1 
ATOM   10943 C CA  . GLU F 2 64  ? -29.197 17.905  -42.696  1.00 62.82  ? 64  GLU J CA  1 
ATOM   10944 C C   . GLU F 2 64  ? -28.545 19.214  -42.283  1.00 57.87  ? 64  GLU J C   1 
ATOM   10945 O O   . GLU F 2 64  ? -28.302 20.091  -43.114  1.00 64.56  ? 64  GLU J O   1 
ATOM   10946 C CB  . GLU F 2 64  ? -28.108 16.847  -42.954  1.00 54.61  ? 64  GLU J CB  1 
ATOM   10947 C CG  . GLU F 2 64  ? -28.595 15.541  -43.571  1.00 63.47  ? 64  GLU J CG  1 
ATOM   10948 C CD  . GLU F 2 64  ? -29.493 14.735  -42.647  1.00 65.37  ? 64  GLU J CD  1 
ATOM   10949 O OE1 . GLU F 2 64  ? -29.554 15.038  -41.436  1.00 64.67  ? 64  GLU J OE1 1 
ATOM   10950 O OE2 . GLU F 2 64  ? -30.143 13.790  -43.137  1.00 69.61  ? 64  GLU J OE2 1 
ATOM   10951 N N   . ALA F 2 65  ? -28.270 19.340  -40.989  1.00 56.53  ? 65  ALA J N   1 
ATOM   10952 C CA  . ALA F 2 65  ? -27.550 20.486  -40.444  1.00 54.39  ? 65  ALA J CA  1 
ATOM   10953 C C   . ALA F 2 65  ? -26.331 19.953  -39.704  1.00 60.90  ? 65  ALA J C   1 
ATOM   10954 O O   . ALA F 2 65  ? -26.468 19.285  -38.673  1.00 63.82  ? 65  ALA J O   1 
ATOM   10955 C CB  . ALA F 2 65  ? -28.446 21.313  -39.525  1.00 48.47  ? 65  ALA J CB  1 
ATOM   10956 N N   . VAL F 2 66  ? -25.144 20.239  -40.230  1.00 54.49  ? 66  VAL J N   1 
ATOM   10957 C CA  . VAL F 2 66  ? -23.898 19.695  -39.703  1.00 54.62  ? 66  VAL J CA  1 
ATOM   10958 C C   . VAL F 2 66  ? -23.139 20.830  -39.031  1.00 64.96  ? 66  VAL J C   1 
ATOM   10959 O O   . VAL F 2 66  ? -22.712 21.786  -39.693  1.00 61.06  ? 66  VAL J O   1 
ATOM   10960 C CB  . VAL F 2 66  ? -23.056 19.035  -40.802  1.00 53.91  ? 66  VAL J CB  1 
ATOM   10961 C CG1 . VAL F 2 66  ? -21.925 18.232  -40.187  1.00 53.69  ? 66  VAL J CG1 1 
ATOM   10962 C CG2 . VAL F 2 66  ? -23.930 18.155  -41.680  1.00 57.26  ? 66  VAL J CG2 1 
ATOM   10963 N N   . GLY F 2 67  ? -22.965 20.722  -37.716  1.00 54.09  ? 67  GLY J N   1 
ATOM   10964 C CA  . GLY F 2 67  ? -22.226 21.706  -36.952  1.00 47.93  ? 67  GLY J CA  1 
ATOM   10965 C C   . GLY F 2 67  ? -21.346 21.064  -35.899  1.00 52.18  ? 67  GLY J C   1 
ATOM   10966 O O   . GLY F 2 67  ? -21.038 19.872  -35.989  1.00 65.61  ? 67  GLY J O   1 
ATOM   10967 N N   . ARG F 2 68  ? -20.927 21.843  -34.901  1.00 49.86  ? 68  ARG J N   1 
ATOM   10968 C CA  . ARG F 2 68  ? -20.090 21.362  -33.799  1.00 52.06  ? 68  ARG J CA  1 
ATOM   10969 C C   . ARG F 2 68  ? -20.721 21.842  -32.493  1.00 53.56  ? 68  ARG J C   1 
ATOM   10970 O O   . ARG F 2 68  ? -20.351 22.892  -31.961  1.00 54.47  ? 68  ARG J O   1 
ATOM   10971 C CB  . ARG F 2 68  ? -18.656 21.856  -33.957  1.00 58.81  ? 68  ARG J CB  1 
ATOM   10972 C CG  . ARG F 2 68  ? -17.935 21.282  -35.165  1.00 58.25  ? 68  ARG J CG  1 
ATOM   10973 C CD  . ARG F 2 68  ? -17.763 19.777  -35.028  1.00 51.45  ? 68  ARG J CD  1 
ATOM   10974 N NE  . ARG F 2 68  ? -16.921 19.216  -36.079  1.00 65.61  ? 68  ARG J NE  1 
ATOM   10975 C CZ  . ARG F 2 68  ? -17.374 18.538  -37.124  1.00 55.46  ? 68  ARG J CZ  1 
ATOM   10976 N NH1 . ARG F 2 68  ? -18.667 18.314  -37.296  1.00 50.62  ? 68  ARG J NH1 1 
ATOM   10977 N NH2 . ARG F 2 68  ? -16.508 18.064  -38.015  1.00 62.17  ? 68  ARG J NH2 1 
ATOM   10978 N N   . GLU F 2 69  ? -21.660 21.057  -31.963  1.00 52.79  ? 69  GLU J N   1 
ATOM   10979 C CA  . GLU F 2 69  ? -22.533 21.506  -30.886  1.00 61.40  ? 69  GLU J CA  1 
ATOM   10980 C C   . GLU F 2 69  ? -22.233 20.839  -29.545  1.00 49.93  ? 69  GLU J C   1 
ATOM   10981 O O   . GLU F 2 69  ? -23.072 20.882  -28.640  1.00 56.04  ? 69  GLU J O   1 
ATOM   10982 C CB  . GLU F 2 69  ? -23.994 21.284  -31.281  1.00 64.62  ? 69  GLU J CB  1 
ATOM   10983 C CG  . GLU F 2 69  ? -24.205 20.125  -32.250  1.00 73.73  ? 69  GLU J CG  1 
ATOM   10984 C CD  . GLU F 2 69  ? -25.562 20.167  -32.935  1.00 92.06  ? 69  GLU J CD  1 
ATOM   10985 O OE1 . GLU F 2 69  ? -26.109 19.085  -33.244  1.00 87.78  ? 69  GLU J OE1 1 
ATOM   10986 O OE2 . GLU F 2 69  ? -26.081 21.281  -33.164  1.00 76.73  ? 69  GLU J OE2 1 
ATOM   10987 N N   . PHE F 2 70  ? -21.056 20.236  -29.388  1.00 52.48  ? 70  PHE J N   1 
ATOM   10988 C CA  . PHE F 2 70  ? -20.653 19.621  -28.129  1.00 52.80  ? 70  PHE J CA  1 
ATOM   10989 C C   . PHE F 2 70  ? -19.479 20.385  -27.528  1.00 57.15  ? 70  PHE J C   1 
ATOM   10990 O O   . PHE F 2 70  ? -18.558 20.789  -28.244  1.00 61.51  ? 70  PHE J O   1 
ATOM   10991 C CB  . PHE F 2 70  ? -20.285 18.147  -28.328  1.00 53.60  ? 70  PHE J CB  1 
ATOM   10992 C CG  . PHE F 2 70  ? -21.389 17.328  -28.934  1.00 49.32  ? 70  PHE J CG  1 
ATOM   10993 C CD1 . PHE F 2 70  ? -22.492 16.959  -28.178  1.00 39.53  ? 70  PHE J CD1 1 
ATOM   10994 C CD2 . PHE F 2 70  ? -21.330 16.934  -30.262  1.00 46.91  ? 70  PHE J CD2 1 
ATOM   10995 C CE1 . PHE F 2 70  ? -23.516 16.212  -28.736  1.00 47.32  ? 70  PHE J CE1 1 
ATOM   10996 C CE2 . PHE F 2 70  ? -22.350 16.185  -30.826  1.00 42.27  ? 70  PHE J CE2 1 
ATOM   10997 C CZ  . PHE F 2 70  ? -23.444 15.824  -30.062  1.00 55.58  ? 70  PHE J CZ  1 
ATOM   10998 N N   . ASN F 2 71  ? -19.518 20.580  -26.209  1.00 60.18  ? 71  ASN J N   1 
ATOM   10999 C CA  . ASN F 2 71  ? -18.547 21.422  -25.525  1.00 59.72  ? 71  ASN J CA  1 
ATOM   11000 C C   . ASN F 2 71  ? -17.292 20.616  -25.184  1.00 53.59  ? 71  ASN J C   1 
ATOM   11001 O O   . ASN F 2 71  ? -17.120 19.475  -25.618  1.00 54.56  ? 71  ASN J O   1 
ATOM   11002 C CB  . ASN F 2 71  ? -19.183 22.067  -24.290  1.00 51.90  ? 71  ASN J CB  1 
ATOM   11003 C CG  . ASN F 2 71  ? -19.624 21.052  -23.240  1.00 60.19  ? 71  ASN J CG  1 
ATOM   11004 O OD1 . ASN F 2 71  ? -18.921 20.084  -22.944  1.00 53.69  ? 71  ASN J OD1 1 
ATOM   11005 N ND2 . ASN F 2 71  ? -20.795 21.285  -22.661  1.00 57.54  ? 71  ASN J ND2 1 
ATOM   11006 N N   . ASN F 2 72  ? -16.402 21.205  -24.383  1.00 51.69  ? 72  ASN J N   1 
ATOM   11007 C CA  . ASN F 2 72  ? -15.111 20.587  -24.104  1.00 68.08  ? 72  ASN J CA  1 
ATOM   11008 C C   . ASN F 2 72  ? -15.189 19.442  -23.100  1.00 63.18  ? 72  ASN J C   1 
ATOM   11009 O O   . ASN F 2 72  ? -14.190 18.740  -22.915  1.00 60.19  ? 72  ASN J O   1 
ATOM   11010 C CB  . ASN F 2 72  ? -14.114 21.641  -23.610  1.00 72.46  ? 72  ASN J CB  1 
ATOM   11011 C CG  . ASN F 2 72  ? -14.690 22.529  -22.526  1.00 91.02  ? 72  ASN J CG  1 
ATOM   11012 O OD1 . ASN F 2 72  ? -15.872 22.875  -22.551  1.00 91.51  ? 72  ASN J OD1 1 
ATOM   11013 N ND2 . ASN F 2 72  ? -13.853 22.907  -21.565  1.00 93.59  ? 72  ASN J ND2 1 
ATOM   11014 N N   . LEU F 2 73  ? -16.334 19.233  -22.449  1.00 56.25  ? 73  LEU J N   1 
ATOM   11015 C CA  . LEU F 2 73  ? -16.530 18.076  -21.585  1.00 50.10  ? 73  LEU J CA  1 
ATOM   11016 C C   . LEU F 2 73  ? -17.432 17.025  -22.227  1.00 51.72  ? 73  LEU J C   1 
ATOM   11017 O O   . LEU F 2 73  ? -17.985 16.170  -21.528  1.00 51.91  ? 73  LEU J O   1 
ATOM   11018 C CB  . LEU F 2 73  ? -17.077 18.511  -20.225  1.00 51.96  ? 73  LEU J CB  1 
ATOM   11019 C CG  . LEU F 2 73  ? -15.982 18.963  -19.252  1.00 68.50  ? 73  LEU J CG  1 
ATOM   11020 C CD1 . LEU F 2 73  ? -16.568 19.509  -17.961  1.00 46.48  ? 73  LEU J CD1 1 
ATOM   11021 C CD2 . LEU F 2 73  ? -15.024 17.814  -18.960  1.00 58.54  ? 73  LEU J CD2 1 
ATOM   11022 N N   . GLU F 2 74  ? -17.588 17.076  -23.546  1.00 54.10  ? 74  GLU J N   1 
ATOM   11023 C CA  . GLU F 2 74  ? -18.320 16.080  -24.319  1.00 46.27  ? 74  GLU J CA  1 
ATOM   11024 C C   . GLU F 2 74  ? -17.475 15.603  -25.494  1.00 44.91  ? 74  GLU J C   1 
ATOM   11025 O O   . GLU F 2 74  ? -17.986 15.336  -26.585  1.00 47.71  ? 74  GLU J O   1 
ATOM   11026 C CB  . GLU F 2 74  ? -19.660 16.638  -24.797  1.00 45.15  ? 74  GLU J CB  1 
ATOM   11027 C CG  . GLU F 2 74  ? -20.624 16.992  -23.668  1.00 53.99  ? 74  GLU J CG  1 
ATOM   11028 C CD  . GLU F 2 74  ? -21.786 17.861  -24.125  1.00 58.01  ? 74  GLU J CD  1 
ATOM   11029 O OE1 . GLU F 2 74  ? -21.588 18.703  -25.026  1.00 59.62  ? 74  GLU J OE1 1 
ATOM   11030 O OE2 . GLU F 2 74  ? -22.899 17.705  -23.580  1.00 64.43  ? 74  GLU J OE2 1 
ATOM   11031 N N   . ARG F 2 75  ? -16.158 15.487  -25.279  1.00 42.81  ? 75  ARG J N   1 
ATOM   11032 C CA  . ARG F 2 75  ? -15.245 15.122  -26.361  1.00 42.24  ? 75  ARG J CA  1 
ATOM   11033 C C   . ARG F 2 75  ? -15.501 13.713  -26.877  1.00 45.21  ? 75  ARG J C   1 
ATOM   11034 O O   . ARG F 2 75  ? -15.324 13.454  -28.073  1.00 51.70  ? 75  ARG J O   1 
ATOM   11035 C CB  . ARG F 2 75  ? -13.792 15.239  -25.897  1.00 50.33  ? 75  ARG J CB  1 
ATOM   11036 C CG  . ARG F 2 75  ? -13.356 16.631  -25.462  1.00 53.11  ? 75  ARG J CG  1 
ATOM   11037 C CD  . ARG F 2 75  ? -13.464 17.645  -26.588  1.00 66.93  ? 75  ARG J CD  1 
ATOM   11038 N NE  . ARG F 2 75  ? -12.479 18.711  -26.439  1.00 85.93  ? 75  ARG J NE  1 
ATOM   11039 C CZ  . ARG F 2 75  ? -12.671 19.970  -26.808  1.00 89.36  ? 75  ARG J CZ  1 
ATOM   11040 N NH1 . ARG F 2 75  ? -13.822 20.372  -27.324  1.00 72.18  ? 75  ARG J NH1 1 
ATOM   11041 N NH2 . ARG F 2 75  ? -11.688 20.851  -26.644  1.00 87.49  ? 75  ARG J NH2 1 
ATOM   11042 N N   . ARG F 2 76  ? -15.887 12.785  -25.997  1.00 49.78  ? 76  ARG J N   1 
ATOM   11043 C CA  . ARG F 2 76  ? -16.158 11.421  -26.439  1.00 42.75  ? 76  ARG J CA  1 
ATOM   11044 C C   . ARG F 2 76  ? -17.299 11.391  -27.448  1.00 44.53  ? 76  ARG J C   1 
ATOM   11045 O O   . ARG F 2 76  ? -17.216 10.701  -28.471  1.00 49.40  ? 76  ARG J O   1 
ATOM   11046 C CB  . ARG F 2 76  ? -16.472 10.533  -25.234  1.00 32.66  ? 76  ARG J CB  1 
ATOM   11047 C CG  . ARG F 2 76  ? -15.280 10.308  -24.315  1.00 46.84  ? 76  ARG J CG  1 
ATOM   11048 C CD  . ARG F 2 76  ? -15.685 9.709   -22.971  1.00 41.28  ? 76  ARG J CD  1 
ATOM   11049 N NE  . ARG F 2 76  ? -16.683 10.526  -22.291  1.00 47.48  ? 76  ARG J NE  1 
ATOM   11050 C CZ  . ARG F 2 76  ? -17.792 10.053  -21.736  1.00 44.10  ? 76  ARG J CZ  1 
ATOM   11051 N NH1 . ARG F 2 76  ? -18.051 8.756   -21.704  1.00 37.45  ? 76  ARG J NH1 1 
ATOM   11052 N NH2 . ARG F 2 76  ? -18.658 10.904  -21.194  1.00 39.41  ? 76  ARG J NH2 1 
ATOM   11053 N N   . ILE F 2 77  ? -18.366 12.146  -27.183  1.00 45.53  ? 77  ILE J N   1 
ATOM   11054 C CA  . ILE F 2 77  ? -19.462 12.256  -28.139  1.00 52.31  ? 77  ILE J CA  1 
ATOM   11055 C C   . ILE F 2 77  ? -19.000 12.985  -29.395  1.00 45.41  ? 77  ILE J C   1 
ATOM   11056 O O   . ILE F 2 77  ? -19.350 12.603  -30.518  1.00 45.79  ? 77  ILE J O   1 
ATOM   11057 C CB  . ILE F 2 77  ? -20.664 12.953  -27.480  1.00 48.44  ? 77  ILE J CB  1 
ATOM   11058 C CG1 . ILE F 2 77  ? -21.224 12.071  -26.366  1.00 49.65  ? 77  ILE J CG1 1 
ATOM   11059 C CG2 . ILE F 2 77  ? -21.735 13.248  -28.509  1.00 54.25  ? 77  ILE J CG2 1 
ATOM   11060 C CD1 . ILE F 2 77  ? -22.043 12.821  -25.341  1.00 62.63  ? 77  ILE J CD1 1 
ATOM   11061 N N   . GLU F 2 78  ? -18.200 14.039  -29.223  1.00 54.64  ? 78  GLU J N   1 
ATOM   11062 C CA  . GLU F 2 78  ? -17.627 14.738  -30.368  1.00 49.22  ? 78  GLU J CA  1 
ATOM   11063 C C   . GLU F 2 78  ? -16.778 13.798  -31.214  1.00 49.80  ? 78  GLU J C   1 
ATOM   11064 O O   . GLU F 2 78  ? -16.845 13.831  -32.449  1.00 43.95  ? 78  GLU J O   1 
ATOM   11065 C CB  . GLU F 2 78  ? -16.804 15.928  -29.879  1.00 46.32  ? 78  GLU J CB  1 
ATOM   11066 C CG  . GLU F 2 78  ? -16.167 16.773  -30.967  1.00 55.32  ? 78  GLU J CG  1 
ATOM   11067 C CD  . GLU F 2 78  ? -15.522 18.028  -30.402  1.00 97.23  ? 78  GLU J CD  1 
ATOM   11068 O OE1 . GLU F 2 78  ? -16.255 18.875  -29.847  1.00 95.93  ? 78  GLU J OE1 1 
ATOM   11069 O OE2 . GLU F 2 78  ? -14.282 18.156  -30.490  1.00 88.49  ? 78  GLU J OE2 1 
ATOM   11070 N N   . ASN F 2 79  ? -15.978 12.946  -30.568  1.00 45.63  ? 79  ASN J N   1 
ATOM   11071 C CA  . ASN F 2 79  ? -15.214 11.949  -31.312  1.00 49.74  ? 79  ASN J CA  1 
ATOM   11072 C C   . ASN F 2 79  ? -16.129 10.962  -32.024  1.00 45.45  ? 79  ASN J C   1 
ATOM   11073 O O   . ASN F 2 79  ? -15.801 10.492  -33.120  1.00 53.18  ? 79  ASN J O   1 
ATOM   11074 C CB  . ASN F 2 79  ? -14.259 11.209  -30.378  1.00 40.37  ? 79  ASN J CB  1 
ATOM   11075 C CG  . ASN F 2 79  ? -13.512 10.094  -31.079  1.00 54.67  ? 79  ASN J CG  1 
ATOM   11076 O OD1 . ASN F 2 79  ? -13.703 8.915   -30.779  1.00 62.54  ? 79  ASN J OD1 1 
ATOM   11077 N ND2 . ASN F 2 79  ? -12.665 10.462  -32.033  1.00 48.86  ? 79  ASN J ND2 1 
ATOM   11078 N N   . LEU F 2 80  ? -17.273 10.631  -31.420  1.00 46.88  ? 80  LEU J N   1 
ATOM   11079 C CA  . LEU F 2 80  ? -18.229 9.748   -32.079  1.00 55.61  ? 80  LEU J CA  1 
ATOM   11080 C C   . LEU F 2 80  ? -18.759 10.373  -33.366  1.00 50.38  ? 80  LEU J C   1 
ATOM   11081 O O   . LEU F 2 80  ? -18.904 9.688   -34.384  1.00 46.02  ? 80  LEU J O   1 
ATOM   11082 C CB  . LEU F 2 80  ? -19.376 9.414   -31.126  1.00 43.73  ? 80  LEU J CB  1 
ATOM   11083 C CG  . LEU F 2 80  ? -20.496 8.530   -31.673  1.00 49.66  ? 80  LEU J CG  1 
ATOM   11084 C CD1 . LEU F 2 80  ? -19.932 7.257   -32.284  1.00 49.25  ? 80  LEU J CD1 1 
ATOM   11085 C CD2 . LEU F 2 80  ? -21.495 8.201   -30.575  1.00 47.04  ? 80  LEU J CD2 1 
ATOM   11086 N N   . ASN F 2 81  ? -19.051 11.675  -33.340  1.00 54.38  ? 81  ASN J N   1 
ATOM   11087 C CA  . ASN F 2 81  ? -19.486 12.349  -34.559  1.00 50.30  ? 81  ASN J CA  1 
ATOM   11088 C C   . ASN F 2 81  ? -18.365 12.405  -35.590  1.00 46.43  ? 81  ASN J C   1 
ATOM   11089 O O   . ASN F 2 81  ? -18.614 12.267  -36.793  1.00 54.82  ? 81  ASN J O   1 
ATOM   11090 C CB  . ASN F 2 81  ? -19.991 13.756  -34.237  1.00 49.50  ? 81  ASN J CB  1 
ATOM   11091 C CG  . ASN F 2 81  ? -20.490 14.490  -35.471  1.00 59.70  ? 81  ASN J CG  1 
ATOM   11092 O OD1 . ASN F 2 81  ? -21.577 14.208  -35.978  1.00 56.70  ? 81  ASN J OD1 1 
ATOM   11093 N ND2 . ASN F 2 81  ? -19.696 15.434  -35.961  1.00 50.67  ? 81  ASN J ND2 1 
ATOM   11094 N N   . LYS F 2 82  ? -17.124 12.611  -35.139  1.00 50.80  ? 82  LYS J N   1 
ATOM   11095 C CA  . LYS F 2 82  ? -15.992 12.633  -36.060  1.00 58.88  ? 82  LYS J CA  1 
ATOM   11096 C C   . LYS F 2 82  ? -15.836 11.294  -36.772  1.00 59.22  ? 82  LYS J C   1 
ATOM   11097 O O   . LYS F 2 82  ? -15.639 11.246  -37.991  1.00 54.31  ? 82  LYS J O   1 
ATOM   11098 C CB  . LYS F 2 82  ? -14.708 12.991  -35.312  1.00 58.01  ? 82  LYS J CB  1 
ATOM   11099 C CG  . LYS F 2 82  ? -13.442 12.683  -36.095  1.00 54.12  ? 82  LYS J CG  1 
ATOM   11100 C CD  . LYS F 2 82  ? -12.193 12.894  -35.255  1.00 55.91  ? 82  LYS J CD  1 
ATOM   11101 C CE  . LYS F 2 82  ? -10.963 12.323  -35.946  1.00 64.62  ? 82  LYS J CE  1 
ATOM   11102 N NZ  . LYS F 2 82  ? -10.802 12.863  -37.328  1.00 59.18  ? 82  LYS J NZ  1 
ATOM   11103 N N   . LYS F 2 83  ? -15.925 10.192  -36.023  1.00 55.13  ? 83  LYS J N   1 
ATOM   11104 C CA  . LYS F 2 83  ? -15.825 8.875   -36.643  1.00 58.28  ? 83  LYS J CA  1 
ATOM   11105 C C   . LYS F 2 83  ? -16.954 8.642   -37.636  1.00 55.79  ? 83  LYS J C   1 
ATOM   11106 O O   . LYS F 2 83  ? -16.752 7.981   -38.662  1.00 54.78  ? 83  LYS J O   1 
ATOM   11107 C CB  . LYS F 2 83  ? -15.823 7.781   -35.573  1.00 56.69  ? 83  LYS J CB  1 
ATOM   11108 C CG  . LYS F 2 83  ? -14.524 7.674   -34.785  1.00 51.42  ? 83  LYS J CG  1 
ATOM   11109 C CD  . LYS F 2 83  ? -14.574 6.516   -33.799  1.00 53.85  ? 83  LYS J CD  1 
ATOM   11110 C CE  . LYS F 2 83  ? -15.646 6.742   -32.746  1.00 50.42  ? 83  LYS J CE  1 
ATOM   11111 N NZ  . LYS F 2 83  ? -15.958 5.500   -31.987  1.00 68.49  ? 83  LYS J NZ  1 
ATOM   11112 N N   . MET F 2 84  ? -18.143 9.176   -37.354  1.00 50.78  ? 84  MET J N   1 
ATOM   11113 C CA  . MET F 2 84  ? -19.263 9.012   -38.272  1.00 58.65  ? 84  MET J CA  1 
ATOM   11114 C C   . MET F 2 84  ? -19.034 9.785   -39.567  1.00 52.41  ? 84  MET J C   1 
ATOM   11115 O O   . MET F 2 84  ? -19.205 9.241   -40.664  1.00 50.54  ? 84  MET J O   1 
ATOM   11116 C CB  . MET F 2 84  ? -20.558 9.460   -37.598  1.00 52.13  ? 84  MET J CB  1 
ATOM   11117 C CG  . MET F 2 84  ? -21.810 8.946   -38.284  1.00 58.62  ? 84  MET J CG  1 
ATOM   11118 S SD  . MET F 2 84  ? -23.229 10.013  -37.992  1.00 66.81  ? 84  MET J SD  1 
ATOM   11119 C CE  . MET F 2 84  ? -22.576 11.579  -38.566  1.00 62.13  ? 84  MET J CE  1 
ATOM   11120 N N   . GLU F 2 85  ? -18.645 11.059  -39.458  1.00 53.88  ? 85  GLU J N   1 
ATOM   11121 C CA  . GLU F 2 85  ? -18.430 11.873  -40.651  1.00 53.71  ? 85  GLU J CA  1 
ATOM   11122 C C   . GLU F 2 85  ? -17.293 11.318  -41.500  1.00 56.75  ? 85  GLU J C   1 
ATOM   11123 O O   . GLU F 2 85  ? -17.394 11.272  -42.731  1.00 53.73  ? 85  GLU J O   1 
ATOM   11124 C CB  . GLU F 2 85  ? -18.148 13.324  -40.259  1.00 51.94  ? 85  GLU J CB  1 
ATOM   11125 C CG  . GLU F 2 85  ? -19.289 13.999  -39.515  1.00 61.39  ? 85  GLU J CG  1 
ATOM   11126 C CD  . GLU F 2 85  ? -19.035 15.474  -39.263  1.00 66.13  ? 85  GLU J CD  1 
ATOM   11127 O OE1 . GLU F 2 85  ? -17.971 15.979  -39.680  1.00 70.19  ? 85  GLU J OE1 1 
ATOM   11128 O OE2 . GLU F 2 85  ? -19.904 16.130  -38.648  1.00 75.15  ? 85  GLU J OE2 1 
ATOM   11129 N N   . ASP F 2 86  ? -16.204 10.890  -40.856  1.00 47.86  ? 86  ASP J N   1 
ATOM   11130 C CA  . ASP F 2 86  ? -15.092 10.292  -41.590  1.00 62.80  ? 86  ASP J CA  1 
ATOM   11131 C C   . ASP F 2 86  ? -15.506 8.983   -42.251  1.00 62.28  ? 86  ASP J C   1 
ATOM   11132 O O   . ASP F 2 86  ? -15.070 8.681   -43.367  1.00 66.84  ? 86  ASP J O   1 
ATOM   11133 C CB  . ASP F 2 86  ? -13.904 10.072  -40.653  1.00 49.35  ? 86  ASP J CB  1 
ATOM   11134 C CG  . ASP F 2 86  ? -13.312 11.375  -40.151  1.00 59.77  ? 86  ASP J CG  1 
ATOM   11135 O OD1 . ASP F 2 86  ? -13.684 12.442  -40.682  1.00 67.46  ? 86  ASP J OD1 1 
ATOM   11136 O OD2 . ASP F 2 86  ? -12.479 11.334  -39.222  1.00 69.89  ? 86  ASP J OD2 1 
ATOM   11137 N N   . GLY F 2 87  ? -16.336 8.188   -41.572  1.00 56.14  ? 87  GLY J N   1 
ATOM   11138 C CA  . GLY F 2 87  ? -16.788 6.936   -42.158  1.00 48.46  ? 87  GLY J CA  1 
ATOM   11139 C C   . GLY F 2 87  ? -17.615 7.139   -43.413  1.00 59.06  ? 87  GLY J C   1 
ATOM   11140 O O   . GLY F 2 87  ? -17.423 6.444   -44.414  1.00 54.31  ? 87  GLY J O   1 
ATOM   11141 N N   . PHE F 2 88  ? -18.548 8.093   -43.379  1.00 53.05  ? 88  PHE J N   1 
ATOM   11142 C CA  . PHE F 2 88  ? -19.371 8.352   -44.556  1.00 63.42  ? 88  PHE J CA  1 
ATOM   11143 C C   . PHE F 2 88  ? -18.548 8.956   -45.687  1.00 60.54  ? 88  PHE J C   1 
ATOM   11144 O O   . PHE F 2 88  ? -18.782 8.647   -46.861  1.00 56.63  ? 88  PHE J O   1 
ATOM   11145 C CB  . PHE F 2 88  ? -20.545 9.261   -44.197  1.00 48.88  ? 88  PHE J CB  1 
ATOM   11146 C CG  . PHE F 2 88  ? -21.649 8.553   -43.471  1.00 52.25  ? 88  PHE J CG  1 
ATOM   11147 C CD1 . PHE F 2 88  ? -22.291 7.473   -44.054  1.00 54.04  ? 88  PHE J CD1 1 
ATOM   11148 C CD2 . PHE F 2 88  ? -22.045 8.962   -42.209  1.00 51.40  ? 88  PHE J CD2 1 
ATOM   11149 C CE1 . PHE F 2 88  ? -23.306 6.812   -43.391  1.00 54.92  ? 88  PHE J CE1 1 
ATOM   11150 C CE2 . PHE F 2 88  ? -23.059 8.305   -41.541  1.00 48.40  ? 88  PHE J CE2 1 
ATOM   11151 C CZ  . PHE F 2 88  ? -23.692 7.229   -42.132  1.00 57.86  ? 88  PHE J CZ  1 
ATOM   11152 N N   . LEU F 2 89  ? -17.588 9.823   -45.357  1.00 60.12  ? 89  LEU J N   1 
ATOM   11153 C CA  . LEU F 2 89  ? -16.721 10.376  -46.392  1.00 65.76  ? 89  LEU J CA  1 
ATOM   11154 C C   . LEU F 2 89  ? -15.900 9.281   -47.059  1.00 64.30  ? 89  LEU J C   1 
ATOM   11155 O O   . LEU F 2 89  ? -15.728 9.284   -48.282  1.00 69.51  ? 89  LEU J O   1 
ATOM   11156 C CB  . LEU F 2 89  ? -15.807 11.450  -45.806  1.00 50.85  ? 89  LEU J CB  1 
ATOM   11157 C CG  . LEU F 2 89  ? -14.907 12.139  -46.835  1.00 65.01  ? 89  LEU J CG  1 
ATOM   11158 C CD1 . LEU F 2 89  ? -15.001 13.633  -46.692  1.00 63.30  ? 89  LEU J CD1 1 
ATOM   11159 C CD2 . LEU F 2 89  ? -13.464 11.694  -46.690  1.00 70.70  ? 89  LEU J CD2 1 
ATOM   11160 N N   . ASP F 2 90  ? -15.383 8.336   -46.270  1.00 62.18  ? 90  ASP J N   1 
ATOM   11161 C CA  . ASP F 2 90  ? -14.637 7.221   -46.846  1.00 65.38  ? 90  ASP J CA  1 
ATOM   11162 C C   . ASP F 2 90  ? -15.533 6.347   -47.716  1.00 63.69  ? 90  ASP J C   1 
ATOM   11163 O O   . ASP F 2 90  ? -15.118 5.898   -48.792  1.00 68.56  ? 90  ASP J O   1 
ATOM   11164 C CB  . ASP F 2 90  ? -13.988 6.395   -45.736  1.00 59.05  ? 90  ASP J CB  1 
ATOM   11165 C CG  . ASP F 2 90  ? -12.925 7.171   -44.978  1.00 78.19  ? 90  ASP J CG  1 
ATOM   11166 O OD1 . ASP F 2 90  ? -12.596 8.301   -45.401  1.00 73.93  ? 90  ASP J OD1 1 
ATOM   11167 O OD2 . ASP F 2 90  ? -12.420 6.654   -43.958  1.00 64.79  ? 90  ASP J OD2 1 
ATOM   11168 N N   . VAL F 2 91  ? -16.763 6.090   -47.266  1.00 53.23  ? 91  VAL J N   1 
ATOM   11169 C CA  . VAL F 2 91  ? -17.694 5.284   -48.055  1.00 58.67  ? 91  VAL J CA  1 
ATOM   11170 C C   . VAL F 2 91  ? -18.045 5.996   -49.354  1.00 71.84  ? 91  VAL J C   1 
ATOM   11171 O O   . VAL F 2 91  ? -18.009 5.403   -50.439  1.00 65.73  ? 91  VAL J O   1 
ATOM   11172 C CB  . VAL F 2 91  ? -18.957 4.963   -47.236  1.00 62.86  ? 91  VAL J CB  1 
ATOM   11173 C CG1 . VAL F 2 91  ? -20.071 4.472   -48.149  1.00 49.03  ? 91  VAL J CG1 1 
ATOM   11174 C CG2 . VAL F 2 91  ? -18.653 3.929   -46.165  1.00 49.06  ? 91  VAL J CG2 1 
ATOM   11175 N N   . TRP F 2 92  ? -18.390 7.283   -49.263  1.00 60.06  ? 92  TRP J N   1 
ATOM   11176 C CA  . TRP F 2 92  ? -18.809 8.011   -50.455  1.00 59.75  ? 92  TRP J CA  1 
ATOM   11177 C C   . TRP F 2 92  ? -17.645 8.229   -51.413  1.00 68.71  ? 92  TRP J C   1 
ATOM   11178 O O   . TRP F 2 92  ? -17.812 8.106   -52.630  1.00 62.78  ? 92  TRP J O   1 
ATOM   11179 C CB  . TRP F 2 92  ? -19.448 9.344   -50.070  1.00 57.91  ? 92  TRP J CB  1 
ATOM   11180 C CG  . TRP F 2 92  ? -20.853 9.212   -49.562  1.00 69.76  ? 92  TRP J CG  1 
ATOM   11181 C CD1 . TRP F 2 92  ? -21.331 9.631   -48.354  1.00 55.25  ? 92  TRP J CD1 1 
ATOM   11182 C CD2 . TRP F 2 92  ? -21.962 8.612   -50.247  1.00 66.51  ? 92  TRP J CD2 1 
ATOM   11183 N NE1 . TRP F 2 92  ? -22.669 9.337   -48.247  1.00 54.74  ? 92  TRP J NE1 1 
ATOM   11184 C CE2 . TRP F 2 92  ? -23.080 8.709   -49.394  1.00 60.34  ? 92  TRP J CE2 1 
ATOM   11185 C CE3 . TRP F 2 92  ? -22.119 8.006   -51.498  1.00 67.23  ? 92  TRP J CE3 1 
ATOM   11186 C CZ2 . TRP F 2 92  ? -24.337 8.223   -49.752  1.00 64.08  ? 92  TRP J CZ2 1 
ATOM   11187 C CZ3 . TRP F 2 92  ? -23.367 7.521   -51.850  1.00 65.74  ? 92  TRP J CZ3 1 
ATOM   11188 C CH2 . TRP F 2 92  ? -24.459 7.633   -50.981  1.00 64.31  ? 92  TRP J CH2 1 
ATOM   11189 N N   . THR F 2 93  ? -16.461 8.552   -50.889  1.00 72.52  ? 93  THR J N   1 
ATOM   11190 C CA  . THR F 2 93  ? -15.306 8.756   -51.758  1.00 54.31  ? 93  THR J CA  1 
ATOM   11191 C C   . THR F 2 93  ? -14.958 7.478   -52.513  1.00 66.80  ? 93  THR J C   1 
ATOM   11192 O O   . THR F 2 93  ? -14.838 7.483   -53.743  1.00 68.82  ? 93  THR J O   1 
ATOM   11193 C CB  . THR F 2 93  ? -14.106 9.239   -50.940  1.00 58.49  ? 93  THR J CB  1 
ATOM   11194 O OG1 . THR F 2 93  ? -14.338 10.581  -50.491  1.00 61.79  ? 93  THR J OG1 1 
ATOM   11195 C CG2 . THR F 2 93  ? -12.835 9.199   -51.773  1.00 62.70  ? 93  THR J CG2 1 
ATOM   11196 N N   . TYR F 2 94  ? -14.826 6.365   -51.791  1.00 61.02  ? 94  TYR J N   1 
ATOM   11197 C CA  . TYR F 2 94  ? -14.400 5.114   -52.412  1.00 65.50  ? 94  TYR J CA  1 
ATOM   11198 C C   . TYR F 2 94  ? -15.401 4.646   -53.462  1.00 78.57  ? 94  TYR J C   1 
ATOM   11199 O O   . TYR F 2 94  ? -15.018 4.249   -54.568  1.00 80.57  ? 94  TYR J O   1 
ATOM   11200 C CB  . TYR F 2 94  ? -14.205 4.049   -51.334  1.00 61.50  ? 94  TYR J CB  1 
ATOM   11201 C CG  . TYR F 2 94  ? -13.636 2.741   -51.831  1.00 66.14  ? 94  TYR J CG  1 
ATOM   11202 C CD1 . TYR F 2 94  ? -12.287 2.622   -52.143  1.00 75.71  ? 94  TYR J CD1 1 
ATOM   11203 C CD2 . TYR F 2 94  ? -14.441 1.617   -51.965  1.00 70.89  ? 94  TYR J CD2 1 
ATOM   11204 C CE1 . TYR F 2 94  ? -11.758 1.425   -52.589  1.00 56.22  ? 94  TYR J CE1 1 
ATOM   11205 C CE2 . TYR F 2 94  ? -13.921 0.414   -52.409  1.00 67.81  ? 94  TYR J CE2 1 
ATOM   11206 C CZ  . TYR F 2 94  ? -12.577 0.325   -52.718  1.00 77.15  ? 94  TYR J CZ  1 
ATOM   11207 O OH  . TYR F 2 94  ? -12.052 -0.867  -53.162  1.00 76.86  ? 94  TYR J OH  1 
ATOM   11208 N N   . ASN F 2 95  ? -16.694 4.696   -53.136  1.00 78.84  ? 95  ASN J N   1 
ATOM   11209 C CA  . ASN F 2 95  ? -17.707 4.241   -54.083  1.00 68.28  ? 95  ASN J CA  1 
ATOM   11210 C C   . ASN F 2 95  ? -17.843 5.198   -55.262  1.00 72.64  ? 95  ASN J C   1 
ATOM   11211 O O   . ASN F 2 95  ? -18.092 4.764   -56.391  1.00 64.47  ? 95  ASN J O   1 
ATOM   11212 C CB  . ASN F 2 95  ? -19.050 4.066   -53.377  1.00 68.21  ? 95  ASN J CB  1 
ATOM   11213 C CG  . ASN F 2 95  ? -19.095 2.822   -52.515  1.00 71.46  ? 95  ASN J CG  1 
ATOM   11214 O OD1 . ASN F 2 95  ? -19.437 2.881   -51.335  1.00 76.67  ? 95  ASN J OD1 1 
ATOM   11215 N ND2 . ASN F 2 95  ? -18.746 1.683   -53.103  1.00 80.32  ? 95  ASN J ND2 1 
ATOM   11216 N N   . ALA F 2 96  ? -17.691 6.501   -55.022  1.00 64.53  ? 96  ALA J N   1 
ATOM   11217 C CA  . ALA F 2 96  ? -17.805 7.461   -56.115  1.00 60.20  ? 96  ALA J CA  1 
ATOM   11218 C C   . ALA F 2 96  ? -16.614 7.372   -57.062  1.00 79.35  ? 96  ALA J C   1 
ATOM   11219 O O   . ALA F 2 96  ? -16.778 7.473   -58.284  1.00 81.68  ? 96  ALA J O   1 
ATOM   11220 C CB  . ALA F 2 96  ? -17.950 8.875   -55.563  1.00 57.91  ? 96  ALA J CB  1 
ATOM   11221 N N   . GLU F 2 97  ? -15.405 7.198   -56.521  1.00 79.11  ? 97  GLU J N   1 
ATOM   11222 C CA  . GLU F 2 97  ? -14.230 7.046   -57.374  1.00 74.03  ? 97  GLU J CA  1 
ATOM   11223 C C   . GLU F 2 97  ? -14.311 5.764   -58.196  1.00 76.21  ? 97  GLU J C   1 
ATOM   11224 O O   . GLU F 2 97  ? -14.038 5.768   -59.402  1.00 77.71  ? 97  GLU J O   1 
ATOM   11225 C CB  . GLU F 2 97  ? -12.953 7.060   -56.529  1.00 75.55  ? 97  GLU J CB  1 
ATOM   11226 C CG  . GLU F 2 97  ? -12.709 8.344   -55.740  1.00 73.78  ? 97  GLU J CG  1 
ATOM   11227 C CD  . GLU F 2 97  ? -12.066 9.449   -56.559  1.00 85.55  ? 97  GLU J CD  1 
ATOM   11228 O OE1 . GLU F 2 97  ? -11.852 9.255   -57.774  1.00 91.81  ? 97  GLU J OE1 1 
ATOM   11229 O OE2 . GLU F 2 97  ? -11.768 10.516  -55.979  1.00 87.38  ? 97  GLU J OE2 1 
ATOM   11230 N N   . LEU F 2 98  ? -14.695 4.654   -57.559  1.00 64.83  ? 98  LEU J N   1 
ATOM   11231 C CA  . LEU F 2 98  ? -14.748 3.380   -58.269  1.00 69.30  ? 98  LEU J CA  1 
ATOM   11232 C C   . LEU F 2 98  ? -15.925 3.314   -59.231  1.00 78.76  ? 98  LEU J C   1 
ATOM   11233 O O   . LEU F 2 98  ? -15.852 2.609   -60.245  1.00 77.01  ? 98  LEU J O   1 
ATOM   11234 C CB  . LEU F 2 98  ? -14.813 2.221   -57.278  1.00 60.13  ? 98  LEU J CB  1 
ATOM   11235 C CG  . LEU F 2 98  ? -13.476 1.816   -56.660  1.00 73.90  ? 98  LEU J CG  1 
ATOM   11236 C CD1 . LEU F 2 98  ? -13.631 0.510   -55.921  1.00 71.82  ? 98  LEU J CD1 1 
ATOM   11237 C CD2 . LEU F 2 98  ? -12.404 1.701   -57.731  1.00 83.52  ? 98  LEU J CD2 1 
ATOM   11238 N N   . LEU F 2 99  ? -17.018 4.017   -58.928  1.00 67.50  ? 99  LEU J N   1 
ATOM   11239 C CA  . LEU F 2 99  ? -18.120 4.103   -59.879  1.00 75.42  ? 99  LEU J CA  1 
ATOM   11240 C C   . LEU F 2 99  ? -17.668 4.762   -61.174  1.00 82.76  ? 99  LEU J C   1 
ATOM   11241 O O   . LEU F 2 99  ? -17.999 4.294   -62.270  1.00 78.95  ? 99  LEU J O   1 
ATOM   11242 C CB  . LEU F 2 99  ? -19.282 4.884   -59.269  1.00 72.44  ? 99  LEU J CB  1 
ATOM   11243 C CG  . LEU F 2 99  ? -20.473 5.132   -60.192  1.00 75.69  ? 99  LEU J CG  1 
ATOM   11244 C CD1 . LEU F 2 99  ? -21.297 3.863   -60.342  1.00 77.11  ? 99  LEU J CD1 1 
ATOM   11245 C CD2 . LEU F 2 99  ? -21.321 6.286   -59.679  1.00 83.20  ? 99  LEU J CD2 1 
ATOM   11246 N N   . VAL F 2 100 ? -16.903 5.849   -61.063  1.00 78.25  ? 100 VAL J N   1 
ATOM   11247 C CA  . VAL F 2 100 ? -16.418 6.551   -62.245  1.00 80.95  ? 100 VAL J CA  1 
ATOM   11248 C C   . VAL F 2 100 ? -15.480 5.662   -63.051  1.00 85.25  ? 100 VAL J C   1 
ATOM   11249 O O   . VAL F 2 100 ? -15.574 5.591   -64.281  1.00 83.02  ? 100 VAL J O   1 
ATOM   11250 C CB  . VAL F 2 100 ? -15.740 7.870   -61.829  1.00 78.93  ? 100 VAL J CB  1 
ATOM   11251 C CG1 . VAL F 2 100 ? -14.916 8.427   -62.970  1.00 78.42  ? 100 VAL J CG1 1 
ATOM   11252 C CG2 . VAL F 2 100 ? -16.786 8.877   -61.377  1.00 68.39  ? 100 VAL J CG2 1 
ATOM   11253 N N   . LEU F 2 101 ? -14.566 4.965   -62.372  1.00 82.30  ? 101 LEU J N   1 
ATOM   11254 C CA  . LEU F 2 101 ? -13.610 4.113   -63.074  1.00 73.97  ? 101 LEU J CA  1 
ATOM   11255 C C   . LEU F 2 101 ? -14.313 2.971   -63.798  1.00 78.33  ? 101 LEU J C   1 
ATOM   11256 O O   . LEU F 2 101 ? -14.030 2.696   -64.970  1.00 83.64  ? 101 LEU J O   1 
ATOM   11257 C CB  . LEU F 2 101 ? -12.573 3.568   -62.091  1.00 72.13  ? 101 LEU J CB  1 
ATOM   11258 C CG  . LEU F 2 101 ? -11.700 4.603   -61.380  1.00 78.85  ? 101 LEU J CG  1 
ATOM   11259 C CD1 . LEU F 2 101 ? -10.688 3.918   -60.476  1.00 76.34  ? 101 LEU J CD1 1 
ATOM   11260 C CD2 . LEU F 2 101 ? -11.003 5.504   -62.390  1.00 70.34  ? 101 LEU J CD2 1 
ATOM   11261 N N   . MET F 2 102 ? -15.238 2.292   -63.115  1.00 74.84  ? 102 MET J N   1 
ATOM   11262 C CA  . MET F 2 102 ? -15.899 1.138   -63.716  1.00 85.25  ? 102 MET J CA  1 
ATOM   11263 C C   . MET F 2 102 ? -16.794 1.543   -64.883  1.00 95.84  ? 102 MET J C   1 
ATOM   11264 O O   . MET F 2 102 ? -16.813 0.866   -65.917  1.00 94.01  ? 102 MET J O   1 
ATOM   11265 C CB  . MET F 2 102 ? -16.705 0.381   -62.661  1.00 77.51  ? 102 MET J CB  1 
ATOM   11266 C CG  . MET F 2 102 ? -15.900 -0.646  -61.880  1.00 89.34  ? 102 MET J CG  1 
ATOM   11267 S SD  . MET F 2 102 ? -16.936 -1.637  -60.785  1.00 108.05 ? 102 MET J SD  1 
ATOM   11268 C CE  . MET F 2 102 ? -17.659 -0.358  -59.762  1.00 88.60  ? 102 MET J CE  1 
ATOM   11269 N N   . GLU F 2 103 ? -17.544 2.639   -64.741  1.00 85.86  ? 103 GLU J N   1 
ATOM   11270 C CA  . GLU F 2 103 ? -18.468 3.024   -65.802  1.00 84.67  ? 103 GLU J CA  1 
ATOM   11271 C C   . GLU F 2 103 ? -17.772 3.741   -66.952  1.00 90.36  ? 103 GLU J C   1 
ATOM   11272 O O   . GLU F 2 103 ? -18.273 3.711   -68.082  1.00 94.07  ? 103 GLU J O   1 
ATOM   11273 C CB  . GLU F 2 103 ? -19.599 3.887   -65.243  1.00 90.36  ? 103 GLU J CB  1 
ATOM   11274 C CG  . GLU F 2 103 ? -20.750 3.059   -64.690  1.00 92.54  ? 103 GLU J CG  1 
ATOM   11275 C CD  . GLU F 2 103 ? -21.110 1.884   -65.585  1.00 98.26  ? 103 GLU J CD  1 
ATOM   11276 O OE1 . GLU F 2 103 ? -21.421 2.109   -66.773  1.00 101.21 ? 103 GLU J OE1 1 
ATOM   11277 O OE2 . GLU F 2 103 ? -21.068 0.733   -65.096  1.00 94.31  ? 103 GLU J OE2 1 
ATOM   11278 N N   . ASN F 2 104 ? -16.634 4.391   -66.696  1.00 91.64  ? 104 ASN J N   1 
ATOM   11279 C CA  . ASN F 2 104 ? -15.841 4.916   -67.803  1.00 85.84  ? 104 ASN J CA  1 
ATOM   11280 C C   . ASN F 2 104 ? -15.347 3.786   -68.694  1.00 95.64  ? 104 ASN J C   1 
ATOM   11281 O O   . ASN F 2 104 ? -15.285 3.930   -69.920  1.00 87.77  ? 104 ASN J O   1 
ATOM   11282 C CB  . ASN F 2 104 ? -14.664 5.738   -67.278  1.00 77.22  ? 104 ASN J CB  1 
ATOM   11283 C CG  . ASN F 2 104 ? -15.036 7.182   -67.013  1.00 77.89  ? 104 ASN J CG  1 
ATOM   11284 O OD1 . ASN F 2 104 ? -16.051 7.672   -67.505  1.00 80.29  ? 104 ASN J OD1 1 
ATOM   11285 N ND2 . ASN F 2 104 ? -14.206 7.876   -66.242  1.00 73.61  ? 104 ASN J ND2 1 
ATOM   11286 N N   . GLU F 2 105 ? -14.988 2.652   -68.090  1.00 94.01  ? 105 GLU J N   1 
ATOM   11287 C CA  . GLU F 2 105 ? -14.590 1.489   -68.873  1.00 87.54  ? 105 GLU J CA  1 
ATOM   11288 C C   . GLU F 2 105 ? -15.748 0.964   -69.713  1.00 104.26 ? 105 GLU J C   1 
ATOM   11289 O O   . GLU F 2 105 ? -15.559 0.583   -70.875  1.00 109.55 ? 105 GLU J O   1 
ATOM   11290 C CB  . GLU F 2 105 ? -14.051 0.399   -67.946  1.00 92.41  ? 105 GLU J CB  1 
ATOM   11291 C CG  . GLU F 2 105 ? -13.698 -0.907  -68.638  1.00 107.76 ? 105 GLU J CG  1 
ATOM   11292 C CD  . GLU F 2 105 ? -12.463 -0.810  -69.521  1.00 128.44 ? 105 GLU J CD  1 
ATOM   11293 O OE1 . GLU F 2 105 ? -11.841 0.272   -69.584  1.00 126.68 ? 105 GLU J OE1 1 
ATOM   11294 O OE2 . GLU F 2 105 ? -12.109 -1.830  -70.152  1.00 135.39 ? 105 GLU J OE2 1 
ATOM   11295 N N   . ARG F 2 106 ? -16.957 0.934   -69.144  1.00 100.37 ? 106 ARG J N   1 
ATOM   11296 C CA  . ARG F 2 106 ? -18.120 0.497   -69.911  1.00 96.71  ? 106 ARG J CA  1 
ATOM   11297 C C   . ARG F 2 106 ? -18.413 1.453   -71.061  1.00 84.87  ? 106 ARG J C   1 
ATOM   11298 O O   . ARG F 2 106 ? -18.771 1.020   -72.162  1.00 89.49  ? 106 ARG J O   1 
ATOM   11299 C CB  . ARG F 2 106 ? -19.342 0.372   -68.998  1.00 95.26  ? 106 ARG J CB  1 
ATOM   11300 C CG  . ARG F 2 106 ? -19.127 -0.491  -67.764  1.00 98.86  ? 106 ARG J CG  1 
ATOM   11301 C CD  . ARG F 2 106 ? -18.948 -1.963  -68.104  1.00 98.57  ? 106 ARG J CD  1 
ATOM   11302 N NE  . ARG F 2 106 ? -20.208 -2.627  -68.421  1.00 109.76 ? 106 ARG J NE  1 
ATOM   11303 C CZ  . ARG F 2 106 ? -20.526 -3.109  -69.615  1.00 112.98 ? 106 ARG J CZ  1 
ATOM   11304 N NH1 . ARG F 2 106 ? -19.692 -3.025  -70.639  1.00 111.45 ? 106 ARG J NH1 1 
ATOM   11305 N NH2 . ARG F 2 106 ? -21.707 -3.697  -69.783  1.00 110.72 ? 106 ARG J NH2 1 
ATOM   11306 N N   . THR F 2 107 ? -18.276 2.760   -70.820  1.00 85.67  ? 107 THR J N   1 
ATOM   11307 C CA  . THR F 2 107 ? -18.549 3.742   -71.865  1.00 83.98  ? 107 THR J CA  1 
ATOM   11308 C C   . THR F 2 107 ? -17.567 3.610   -73.023  1.00 99.98  ? 107 THR J C   1 
ATOM   11309 O O   . THR F 2 107 ? -17.966 3.632   -74.193  1.00 101.17 ? 107 THR J O   1 
ATOM   11310 C CB  . THR F 2 107 ? -18.502 5.156   -71.284  1.00 87.74  ? 107 THR J CB  1 
ATOM   11311 O OG1 . THR F 2 107 ? -19.582 5.333   -70.359  1.00 87.22  ? 107 THR J OG1 1 
ATOM   11312 C CG2 . THR F 2 107 ? -18.609 6.192   -72.392  1.00 81.27  ? 107 THR J CG2 1 
ATOM   11313 N N   . LEU F 2 108 ? -16.274 3.463   -72.719  1.00 96.08  ? 108 LEU J N   1 
ATOM   11314 C CA  . LEU F 2 108 ? -15.273 3.373   -73.775  1.00 98.52  ? 108 LEU J CA  1 
ATOM   11315 C C   . LEU F 2 108 ? -15.386 2.083   -74.575  1.00 106.13 ? 108 LEU J C   1 
ATOM   11316 O O   . LEU F 2 108 ? -14.889 2.026   -75.704  1.00 111.96 ? 108 LEU J O   1 
ATOM   11317 C CB  . LEU F 2 108 ? -13.868 3.506   -73.185  1.00 92.25  ? 108 LEU J CB  1 
ATOM   11318 C CG  . LEU F 2 108 ? -13.534 4.878   -72.596  1.00 87.64  ? 108 LEU J CG  1 
ATOM   11319 C CD1 . LEU F 2 108 ? -12.051 4.986   -72.275  1.00 90.96  ? 108 LEU J CD1 1 
ATOM   11320 C CD2 . LEU F 2 108 ? -13.968 5.991   -73.540  1.00 79.53  ? 108 LEU J CD2 1 
ATOM   11321 N N   . ASP F 2 109 ? -16.017 1.050   -74.019  1.00 98.01  ? 109 ASP J N   1 
ATOM   11322 C CA  . ASP F 2 109 ? -16.315 -0.157  -74.776  1.00 101.77 ? 109 ASP J CA  1 
ATOM   11323 C C   . ASP F 2 109 ? -17.710 -0.138  -75.384  1.00 107.94 ? 109 ASP J C   1 
ATOM   11324 O O   . ASP F 2 109 ? -18.002 -0.965  -76.255  1.00 110.98 ? 109 ASP J O   1 
ATOM   11325 C CB  . ASP F 2 109 ? -16.153 -1.395  -73.889  1.00 100.93 ? 109 ASP J CB  1 
ATOM   11326 C CG  . ASP F 2 109 ? -14.775 -1.486  -73.269  1.00 118.53 ? 109 ASP J CG  1 
ATOM   11327 O OD1 . ASP F 2 109 ? -14.456 -2.541  -72.684  1.00 121.67 ? 109 ASP J OD1 1 
ATOM   11328 O OD2 . ASP F 2 109 ? -14.018 -0.496  -73.352  1.00 118.02 ? 109 ASP J OD2 1 
ATOM   11329 N N   . PHE F 2 110 ? -18.575 0.775   -74.940  1.00 97.92  ? 110 PHE J N   1 
ATOM   11330 C CA  . PHE F 2 110 ? -19.854 0.978   -75.611  1.00 93.53  ? 110 PHE J CA  1 
ATOM   11331 C C   . PHE F 2 110 ? -19.646 1.580   -76.996  1.00 106.21 ? 110 PHE J C   1 
ATOM   11332 O O   . PHE F 2 110 ? -20.235 1.120   -77.981  1.00 94.75  ? 110 PHE J O   1 
ATOM   11333 C CB  . PHE F 2 110 ? -20.752 1.869   -74.751  1.00 88.01  ? 110 PHE J CB  1 
ATOM   11334 C CG  . PHE F 2 110 ? -22.082 2.183   -75.373  1.00 80.97  ? 110 PHE J CG  1 
ATOM   11335 C CD1 . PHE F 2 110 ? -22.925 1.168   -75.795  1.00 86.72  ? 110 PHE J CD1 1 
ATOM   11336 C CD2 . PHE F 2 110 ? -22.501 3.497   -75.511  1.00 82.20  ? 110 PHE J CD2 1 
ATOM   11337 C CE1 . PHE F 2 110 ? -24.154 1.458   -76.359  1.00 78.16  ? 110 PHE J CE1 1 
ATOM   11338 C CE2 . PHE F 2 110 ? -23.728 3.792   -76.071  1.00 76.31  ? 110 PHE J CE2 1 
ATOM   11339 C CZ  . PHE F 2 110 ? -24.555 2.773   -76.497  1.00 78.67  ? 110 PHE J CZ  1 
ATOM   11340 N N   . HIS F 2 111 ? -18.800 2.610   -77.088  1.00 105.60 ? 111 HIS J N   1 
ATOM   11341 C CA  . HIS F 2 111 ? -18.456 3.180   -78.386  1.00 105.53 ? 111 HIS J CA  1 
ATOM   11342 C C   . HIS F 2 111 ? -17.683 2.183   -79.239  1.00 110.68 ? 111 HIS J C   1 
ATOM   11343 O O   . HIS F 2 111 ? -17.867 2.128   -80.461  1.00 115.33 ? 111 HIS J O   1 
ATOM   11344 C CB  . HIS F 2 111 ? -17.646 4.461   -78.197  1.00 104.16 ? 111 HIS J CB  1 
ATOM   11345 C CG  . HIS F 2 111 ? -18.383 5.540   -77.469  1.00 102.98 ? 111 HIS J CG  1 
ATOM   11346 N ND1 . HIS F 2 111 ? -19.713 5.818   -77.700  1.00 100.48 ? 111 HIS J ND1 1 
ATOM   11347 C CD2 . HIS F 2 111 ? -17.979 6.406   -76.510  1.00 97.46  ? 111 HIS J CD2 1 
ATOM   11348 C CE1 . HIS F 2 111 ? -20.095 6.812   -76.918  1.00 102.40 ? 111 HIS J CE1 1 
ATOM   11349 N NE2 . HIS F 2 111 ? -19.061 7.187   -76.186  1.00 101.93 ? 111 HIS J NE2 1 
ATOM   11350 N N   . ASP F 2 112 ? -16.805 1.396   -78.613  1.00 111.72 ? 112 ASP J N   1 
ATOM   11351 C CA  . ASP F 2 112 ? -16.069 0.372   -79.346  1.00 113.06 ? 112 ASP J CA  1 
ATOM   11352 C C   . ASP F 2 112 ? -17.019 -0.653  -79.952  1.00 114.54 ? 112 ASP J C   1 
ATOM   11353 O O   . ASP F 2 112 ? -16.847 -1.069  -81.104  1.00 122.66 ? 112 ASP J O   1 
ATOM   11354 C CB  . ASP F 2 112 ? -15.059 -0.302  -78.415  1.00 125.54 ? 112 ASP J CB  1 
ATOM   11355 C CG  . ASP F 2 112 ? -13.984 -1.066  -79.164  1.00 141.56 ? 112 ASP J CG  1 
ATOM   11356 O OD1 . ASP F 2 112 ? -14.326 -1.906  -80.020  1.00 149.55 ? 112 ASP J OD1 1 
ATOM   11357 O OD2 . ASP F 2 112 ? -12.789 -0.821  -78.897  1.00 146.15 ? 112 ASP J OD2 1 
ATOM   11358 N N   . SER F 2 113 ? -18.031 -1.069  -79.190  1.00 116.10 ? 113 SER J N   1 
ATOM   11359 C CA  . SER F 2 113 ? -19.015 -2.012  -79.711  1.00 115.21 ? 113 SER J CA  1 
ATOM   11360 C C   . SER F 2 113 ? -19.850 -1.395  -80.826  1.00 108.28 ? 113 SER J C   1 
ATOM   11361 O O   . SER F 2 113 ? -20.171 -2.069  -81.812  1.00 107.15 ? 113 SER J O   1 
ATOM   11362 C CB  . SER F 2 113 ? -19.918 -2.500  -78.583  1.00 117.06 ? 113 SER J CB  1 
ATOM   11363 O OG  . SER F 2 113 ? -21.145 -2.972  -79.102  1.00 122.00 ? 113 SER J OG  1 
ATOM   11364 N N   . ASN F 2 114 ? -20.227 -0.122  -80.680  1.00 103.78 ? 114 ASN J N   1 
ATOM   11365 C CA  . ASN F 2 114 ? -21.073 0.518   -81.683  1.00 108.95 ? 114 ASN J CA  1 
ATOM   11366 C C   . ASN F 2 114 ? -20.370 0.602   -83.032  1.00 114.79 ? 114 ASN J C   1 
ATOM   11367 O O   . ASN F 2 114 ? -20.993 0.383   -84.079  1.00 111.29 ? 114 ASN J O   1 
ATOM   11368 C CB  . ASN F 2 114 ? -21.493 1.910   -81.211  1.00 102.34 ? 114 ASN J CB  1 
ATOM   11369 C CG  . ASN F 2 114 ? -22.406 1.866   -80.001  1.00 101.00 ? 114 ASN J CG  1 
ATOM   11370 O OD1 . ASN F 2 114 ? -22.892 0.804   -79.614  1.00 99.15  ? 114 ASN J OD1 1 
ATOM   11371 N ND2 . ASN F 2 114 ? -22.653 3.027   -79.404  1.00 93.74  ? 114 ASN J ND2 1 
ATOM   11372 N N   . VAL F 2 115 ? -19.075 0.926   -83.029  1.00 117.02 ? 115 VAL J N   1 
ATOM   11373 C CA  . VAL F 2 115 ? -18.317 0.970   -84.277  1.00 112.10 ? 115 VAL J CA  1 
ATOM   11374 C C   . VAL F 2 115 ? -18.259 -0.411  -84.914  1.00 118.69 ? 115 VAL J C   1 
ATOM   11375 O O   . VAL F 2 115 ? -18.458 -0.561  -86.127  1.00 120.23 ? 115 VAL J O   1 
ATOM   11376 C CB  . VAL F 2 115 ? -16.907 1.535   -84.027  1.00 120.54 ? 115 VAL J CB  1 
ATOM   11377 C CG1 . VAL F 2 115 ? -16.033 1.331   -85.253  1.00 130.57 ? 115 VAL J CG1 1 
ATOM   11378 C CG2 . VAL F 2 115 ? -16.985 3.007   -83.672  1.00 121.31 ? 115 VAL J CG2 1 
ATOM   11379 N N   . LYS F 2 116 ? -17.980 -1.442  -84.111  1.00 108.06 ? 116 LYS J N   1 
ATOM   11380 C CA  . LYS F 2 116 ? -17.968 -2.800  -84.643  1.00 106.41 ? 116 LYS J CA  1 
ATOM   11381 C C   . LYS F 2 116 ? -19.351 -3.196  -85.154  1.00 120.20 ? 116 LYS J C   1 
ATOM   11382 O O   . LYS F 2 116 ? -19.477 -3.743  -86.255  1.00 127.45 ? 116 LYS J O   1 
ATOM   11383 C CB  . LYS F 2 116 ? -17.441 -3.775  -83.577  1.00 111.59 ? 116 LYS J CB  1 
ATOM   11384 C CG  . LYS F 2 116 ? -18.011 -5.196  -83.604  1.00 120.17 ? 116 LYS J CG  1 
ATOM   11385 C CD  . LYS F 2 116 ? -17.706 -5.962  -84.883  1.00 113.71 ? 116 LYS J CD  1 
ATOM   11386 C CE  . LYS F 2 116 ? -18.805 -6.984  -85.133  1.00 124.90 ? 116 LYS J CE  1 
ATOM   11387 N NZ  . LYS F 2 116 ? -20.183 -6.380  -85.116  1.00 127.47 ? 116 LYS J NZ  1 
ATOM   11388 N N   . ASN F 2 117 ? -20.407 -2.889  -84.392  1.00 121.47 ? 117 ASN J N   1 
ATOM   11389 C CA  . ASN F 2 117 ? -21.752 -3.230  -84.848  1.00 120.86 ? 117 ASN J CA  1 
ATOM   11390 C C   . ASN F 2 117 ? -22.117 -2.520  -86.144  1.00 127.98 ? 117 ASN J C   1 
ATOM   11391 O O   . ASN F 2 117 ? -22.961 -3.022  -86.895  1.00 133.46 ? 117 ASN J O   1 
ATOM   11392 C CB  . ASN F 2 117 ? -22.785 -2.914  -83.764  1.00 110.48 ? 117 ASN J CB  1 
ATOM   11393 C CG  . ASN F 2 117 ? -22.663 -3.830  -82.568  1.00 117.83 ? 117 ASN J CG  1 
ATOM   11394 O OD1 . ASN F 2 117 ? -22.203 -4.965  -82.689  1.00 124.57 ? 117 ASN J OD1 1 
ATOM   11395 N ND2 . ASN F 2 117 ? -23.064 -3.340  -81.404  1.00 125.44 ? 117 ASN J ND2 1 
ATOM   11396 N N   . LEU F 2 118 ? -21.494 -1.378  -86.433  1.00 123.33 ? 118 LEU J N   1 
ATOM   11397 C CA  . LEU F 2 118 ? -21.710 -0.697  -87.702  1.00 116.59 ? 118 LEU J CA  1 
ATOM   11398 C C   . LEU F 2 118 ? -20.815 -1.229  -88.814  1.00 125.26 ? 118 LEU J C   1 
ATOM   11399 O O   . LEU F 2 118 ? -21.222 -1.226  -89.982  1.00 121.98 ? 118 LEU J O   1 
ATOM   11400 C CB  . LEU F 2 118 ? -21.488 0.808   -87.534  1.00 108.88 ? 118 LEU J CB  1 
ATOM   11401 C CG  . LEU F 2 118 ? -21.942 1.662   -88.715  1.00 108.88 ? 118 LEU J CG  1 
ATOM   11402 C CD1 . LEU F 2 118 ? -23.311 1.199   -89.177  1.00 105.67 ? 118 LEU J CD1 1 
ATOM   11403 C CD2 . LEU F 2 118 ? -21.967 3.135   -88.339  1.00 112.90 ? 118 LEU J CD2 1 
ATOM   11404 N N   . TYR F 2 119 ? -19.605 -1.680  -88.478  1.00 123.58 ? 119 TYR J N   1 
ATOM   11405 C CA  . TYR F 2 119 ? -18.744 -2.312  -89.472  1.00 123.99 ? 119 TYR J CA  1 
ATOM   11406 C C   . TYR F 2 119 ? -19.350 -3.618  -89.974  1.00 127.45 ? 119 TYR J C   1 
ATOM   11407 O O   . TYR F 2 119 ? -19.264 -3.928  -91.167  1.00 132.19 ? 119 TYR J O   1 
ATOM   11408 C CB  . TYR F 2 119 ? -17.353 -2.547  -88.881  1.00 130.80 ? 119 TYR J CB  1 
ATOM   11409 C CG  . TYR F 2 119 ? -16.385 -3.266  -89.797  1.00 134.08 ? 119 TYR J CG  1 
ATOM   11410 C CD1 . TYR F 2 119 ? -15.624 -2.566  -90.725  1.00 139.78 ? 119 TYR J CD1 1 
ATOM   11411 C CD2 . TYR F 2 119 ? -16.218 -4.643  -89.720  1.00 131.56 ? 119 TYR J CD2 1 
ATOM   11412 C CE1 . TYR F 2 119 ? -14.732 -3.219  -91.556  1.00 142.41 ? 119 TYR J CE1 1 
ATOM   11413 C CE2 . TYR F 2 119 ? -15.332 -5.304  -90.548  1.00 133.86 ? 119 TYR J CE2 1 
ATOM   11414 C CZ  . TYR F 2 119 ? -14.592 -4.588  -91.464  1.00 140.46 ? 119 TYR J CZ  1 
ATOM   11415 O OH  . TYR F 2 119 ? -13.708 -5.245  -92.288  1.00 142.19 ? 119 TYR J OH  1 
ATOM   11416 N N   . ASP F 2 120 ? -19.962 -4.398  -89.077  1.00 124.66 ? 120 ASP J N   1 
ATOM   11417 C CA  . ASP F 2 120 ? -20.604 -5.639  -89.496  1.00 121.80 ? 120 ASP J CA  1 
ATOM   11418 C C   . ASP F 2 120 ? -21.914 -5.381  -90.227  1.00 124.37 ? 120 ASP J C   1 
ATOM   11419 O O   . ASP F 2 120 ? -22.305 -6.177  -91.088  1.00 125.12 ? 120 ASP J O   1 
ATOM   11420 C CB  . ASP F 2 120 ? -20.846 -6.547  -88.290  1.00 128.51 ? 120 ASP J CB  1 
ATOM   11421 C CG  . ASP F 2 120 ? -19.924 -7.749  -88.274  1.00 129.23 ? 120 ASP J CG  1 
ATOM   11422 O OD1 . ASP F 2 120 ? -18.952 -7.761  -89.058  1.00 126.70 ? 120 ASP J OD1 1 
ATOM   11423 O OD2 . ASP F 2 120 ? -20.171 -8.681  -87.479  1.00 127.75 ? 120 ASP J OD2 1 
ATOM   11424 N N   . LYS F 2 121 ? -22.609 -4.290  -89.894  1.00 120.98 ? 121 LYS J N   1 
ATOM   11425 C CA  . LYS F 2 121 ? -23.822 -3.941  -90.626  1.00 115.28 ? 121 LYS J CA  1 
ATOM   11426 C C   . LYS F 2 121 ? -23.514 -3.690  -92.096  1.00 125.51 ? 121 LYS J C   1 
ATOM   11427 O O   . LYS F 2 121 ? -24.265 -4.120  -92.980  1.00 126.10 ? 121 LYS J O   1 
ATOM   11428 C CB  . LYS F 2 121 ? -24.485 -2.716  -89.995  1.00 108.85 ? 121 LYS J CB  1 
ATOM   11429 C CG  . LYS F 2 121 ? -25.501 -2.030  -90.893  1.00 107.46 ? 121 LYS J CG  1 
ATOM   11430 C CD  . LYS F 2 121 ? -26.337 -1.028  -90.119  1.00 100.67 ? 121 LYS J CD  1 
ATOM   11431 C CE  . LYS F 2 121 ? -27.168 -0.169  -91.055  1.00 113.11 ? 121 LYS J CE  1 
ATOM   11432 N NZ  . LYS F 2 121 ? -26.969 1.279   -90.773  1.00 113.75 ? 121 LYS J NZ  1 
ATOM   11433 N N   . VAL F 2 122 ? -22.409 -2.998  -92.375  1.00 126.97 ? 122 VAL J N   1 
ATOM   11434 C CA  . VAL F 2 122 ? -21.985 -2.793  -93.756  1.00 117.30 ? 122 VAL J CA  1 
ATOM   11435 C C   . VAL F 2 122 ? -21.524 -4.107  -94.378  1.00 120.76 ? 122 VAL J C   1 
ATOM   11436 O O   . VAL F 2 122 ? -21.872 -4.420  -95.523  1.00 123.14 ? 122 VAL J O   1 
ATOM   11437 C CB  . VAL F 2 122 ? -20.890 -1.713  -93.816  1.00 116.41 ? 122 VAL J CB  1 
ATOM   11438 C CG1 . VAL F 2 122 ? -20.009 -1.905  -95.039  1.00 130.35 ? 122 VAL J CG1 1 
ATOM   11439 C CG2 . VAL F 2 122 ? -21.518 -0.327  -93.825  1.00 104.41 ? 122 VAL J CG2 1 
ATOM   11440 N N   . ARG F 2 123 ? -20.747 -4.901  -93.634  1.00 118.68 ? 123 ARG J N   1 
ATOM   11441 C CA  . ARG F 2 123 ? -20.162 -6.118  -94.195  1.00 122.17 ? 123 ARG J CA  1 
ATOM   11442 C C   . ARG F 2 123 ? -21.236 -7.106  -94.636  1.00 130.51 ? 123 ARG J C   1 
ATOM   11443 O O   . ARG F 2 123 ? -21.188 -7.632  -95.754  1.00 127.69 ? 123 ARG J O   1 
ATOM   11444 C CB  . ARG F 2 123 ? -19.221 -6.763  -93.173  1.00 112.02 ? 123 ARG J CB  1 
ATOM   11445 C CG  . ARG F 2 123 ? -18.837 -8.215  -93.473  1.00 114.55 ? 123 ARG J CG  1 
ATOM   11446 C CD  . ARG F 2 123 ? -19.727 -9.199  -92.714  1.00 122.18 ? 123 ARG J CD  1 
ATOM   11447 N NE  . ARG F 2 123 ? -19.300 -10.583 -92.877  1.00 128.95 ? 123 ARG J NE  1 
ATOM   11448 C CZ  . ARG F 2 123 ? -18.359 -11.161 -92.143  1.00 127.16 ? 123 ARG J CZ  1 
ATOM   11449 N NH1 . ARG F 2 123 ? -17.707 -10.494 -91.206  1.00 126.02 ? 123 ARG J NH1 1 
ATOM   11450 N NH2 . ARG F 2 123 ? -18.064 -12.441 -92.356  1.00 116.07 ? 123 ARG J NH2 1 
ATOM   11451 N N   . LEU F 2 124 ? -22.217 -7.371  -93.769  1.00 131.94 ? 124 LEU J N   1 
ATOM   11452 C CA  . LEU F 2 124 ? -23.206 -8.405  -94.058  1.00 128.83 ? 124 LEU J CA  1 
ATOM   11453 C C   . LEU F 2 124 ? -24.069 -8.069  -95.266  1.00 130.04 ? 124 LEU J C   1 
ATOM   11454 O O   . LEU F 2 124 ? -24.664 -8.977  -95.856  1.00 124.32 ? 124 LEU J O   1 
ATOM   11455 C CB  . LEU F 2 124 ? -24.090 -8.649  -92.833  1.00 119.86 ? 124 LEU J CB  1 
ATOM   11456 C CG  . LEU F 2 124 ? -23.547 -9.665  -91.826  1.00 119.50 ? 124 LEU J CG  1 
ATOM   11457 C CD1 . LEU F 2 124 ? -24.428 -9.727  -90.588  1.00 123.63 ? 124 LEU J CD1 1 
ATOM   11458 C CD2 . LEU F 2 124 ? -23.429 -11.039 -92.470  1.00 109.24 ? 124 LEU J CD2 1 
ATOM   11459 N N   . GLN F 2 125 ? -24.163 -6.793  -95.640  1.00 129.46 ? 125 GLN J N   1 
ATOM   11460 C CA  . GLN F 2 125 ? -24.854 -6.440  -96.873  1.00 130.61 ? 125 GLN J CA  1 
ATOM   11461 C C   . GLN F 2 125 ? -23.991 -6.718  -98.098  1.00 137.26 ? 125 GLN J C   1 
ATOM   11462 O O   . GLN F 2 125 ? -24.506 -7.129  -99.144  1.00 137.81 ? 125 GLN J O   1 
ATOM   11463 C CB  . GLN F 2 125 ? -25.269 -4.969  -96.844  1.00 120.16 ? 125 GLN J CB  1 
ATOM   11464 C CG  . GLN F 2 125 ? -26.182 -4.601  -95.688  1.00 119.85 ? 125 GLN J CG  1 
ATOM   11465 C CD  . GLN F 2 125 ? -26.762 -3.207  -95.826  1.00 126.49 ? 125 GLN J CD  1 
ATOM   11466 O OE1 . GLN F 2 125 ? -27.858 -3.031  -96.355  1.00 127.11 ? 125 GLN J OE1 1 
ATOM   11467 N NE2 . GLN F 2 125 ? -26.027 -2.207  -95.349  1.00 117.65 ? 125 GLN J NE2 1 
ATOM   11468 N N   . LEU F 2 126 ? -22.679 -6.501  -97.989  1.00 135.90 ? 126 LEU J N   1 
ATOM   11469 C CA  . LEU F 2 126 ? -21.818 -6.585  -99.164  1.00 132.05 ? 126 LEU J CA  1 
ATOM   11470 C C   . LEU F 2 126 ? -21.373 -8.018  -99.435  1.00 133.37 ? 126 LEU J C   1 
ATOM   11471 O O   . LEU F 2 126 ? -21.374 -8.462  -100.587 1.00 136.13 ? 126 LEU J O   1 
ATOM   11472 C CB  . LEU F 2 126 ? -20.612 -5.662  -98.992  1.00 136.22 ? 126 LEU J CB  1 
ATOM   11473 C CG  . LEU F 2 126 ? -20.950 -4.222  -98.588  1.00 138.28 ? 126 LEU J CG  1 
ATOM   11474 C CD1 . LEU F 2 126 ? -19.699 -3.354  -98.567  1.00 144.00 ? 126 LEU J CD1 1 
ATOM   11475 C CD2 . LEU F 2 126 ? -22.010 -3.628  -99.504  1.00 128.98 ? 126 LEU J CD2 1 
ATOM   11476 N N   . ARG F 2 127 ? -20.997 -8.753  -98.389  1.00 139.36 ? 127 ARG J N   1 
ATOM   11477 C CA  . ARG F 2 127 ? -20.640 -10.180 -98.472  1.00 138.34 ? 127 ARG J CA  1 
ATOM   11478 C C   . ARG F 2 127 ? -19.453 -10.312 -99.426  1.00 137.07 ? 127 ARG J C   1 
ATOM   11479 O O   . ARG F 2 127 ? -18.464 -9.580  -99.261  1.00 132.22 ? 127 ARG J O   1 
ATOM   11480 C CB  . ARG F 2 127 ? -21.881 -10.988 -98.840  1.00 128.91 ? 127 ARG J CB  1 
ATOM   11481 C CG  . ARG F 2 127 ? -23.156 -10.450 -98.212  1.00 128.13 ? 127 ARG J CG  1 
ATOM   11482 C CD  . ARG F 2 127 ? -24.186 -11.536 -97.990  1.00 125.66 ? 127 ARG J CD  1 
ATOM   11483 N NE  . ARG F 2 127 ? -25.183 -11.646 -99.048  1.00 127.06 ? 127 ARG J NE  1 
ATOM   11484 C CZ  . ARG F 2 127 ? -26.248 -10.863 -99.163  1.00 134.65 ? 127 ARG J CZ  1 
ATOM   11485 N NH1 . ARG F 2 127 ? -26.408 -9.793  -98.401  1.00 131.42 ? 127 ARG J NH1 1 
ATOM   11486 N NH2 . ARG F 2 127 ? -27.184 -11.171 -100.054 1.00 134.62 ? 127 ARG J NH2 1 
ATOM   11487 N N   . ASP F 2 128 ? -19.497 -11.206 -100.413 1.00 148.74 ? 128 ASP J N   1 
ATOM   11488 C CA  . ASP F 2 128 ? -18.424 -11.347 -101.389 1.00 153.17 ? 128 ASP J CA  1 
ATOM   11489 C C   . ASP F 2 128 ? -18.568 -10.392 -102.566 1.00 148.05 ? 128 ASP J C   1 
ATOM   11490 O O   . ASP F 2 128 ? -17.709 -10.391 -103.454 1.00 143.50 ? 128 ASP J O   1 
ATOM   11491 C CB  . ASP F 2 128 ? -18.355 -12.793 -101.897 1.00 152.44 ? 128 ASP J CB  1 
ATOM   11492 C CG  . ASP F 2 128 ? -19.671 -13.275 -102.483 1.00 152.68 ? 128 ASP J CG  1 
ATOM   11493 O OD1 . ASP F 2 128 ? -20.664 -12.518 -102.441 1.00 151.48 ? 128 ASP J OD1 1 
ATOM   11494 O OD2 . ASP F 2 128 ? -19.712 -14.419 -102.987 1.00 146.33 ? 128 ASP J OD2 1 
ATOM   11495 N N   . ASN F 2 129 ? -19.635 -9.591  -102.598 1.00 147.47 ? 129 ASN J N   1 
ATOM   11496 C CA  . ASN F 2 129 ? -19.781 -8.562  -103.619 1.00 146.26 ? 129 ASN J CA  1 
ATOM   11497 C C   . ASN F 2 129 ? -18.743 -7.455  -103.466 1.00 150.52 ? 129 ASN J C   1 
ATOM   11498 O O   . ASN F 2 129 ? -18.500 -6.710  -104.421 1.00 147.75 ? 129 ASN J O   1 
ATOM   11499 C CB  . ASN F 2 129 ? -21.206 -7.997  -103.567 1.00 142.66 ? 129 ASN J CB  1 
ATOM   11500 C CG  . ASN F 2 129 ? -21.408 -6.813  -104.482 1.00 146.68 ? 129 ASN J CG  1 
ATOM   11501 O OD1 . ASN F 2 129 ? -21.259 -5.665  -104.068 1.00 147.20 ? 129 ASN J OD1 1 
ATOM   11502 N ND2 . ASN F 2 129 ? -21.762 -7.084  -105.732 1.00 149.92 ? 129 ASN J ND2 1 
ATOM   11503 N N   . ALA F 2 130 ? -18.116 -7.343  -102.296 1.00 155.42 ? 130 ALA J N   1 
ATOM   11504 C CA  . ALA F 2 130 ? -17.041 -6.393  -102.044 1.00 146.93 ? 130 ALA J CA  1 
ATOM   11505 C C   . ALA F 2 130 ? -15.876 -7.124  -101.385 1.00 142.38 ? 130 ALA J C   1 
ATOM   11506 O O   . ALA F 2 130 ? -15.961 -8.313  -101.063 1.00 132.12 ? 130 ALA J O   1 
ATOM   11507 C CB  . ALA F 2 130 ? -17.524 -5.224  -101.176 1.00 140.03 ? 130 ALA J CB  1 
ATOM   11508 N N   . LYS F 2 131 ? -14.774 -6.403  -101.182 1.00 147.64 ? 131 LYS J N   1 
ATOM   11509 C CA  . LYS F 2 131 ? -13.563 -6.968  -100.605 1.00 147.49 ? 131 LYS J CA  1 
ATOM   11510 C C   . LYS F 2 131 ? -13.123 -6.134  -99.411  1.00 148.02 ? 131 LYS J C   1 
ATOM   11511 O O   . LYS F 2 131 ? -13.137 -4.900  -99.466  1.00 143.78 ? 131 LYS J O   1 
ATOM   11512 C CB  . LYS F 2 131 ? -12.432 -7.032  -101.643 1.00 146.46 ? 131 LYS J CB  1 
ATOM   11513 C CG  . LYS F 2 131 ? -11.252 -7.896  -101.231 1.00 146.38 ? 131 LYS J CG  1 
ATOM   11514 C CD  . LYS F 2 131 ? -10.129 -7.835  -102.255 1.00 145.64 ? 131 LYS J CD  1 
ATOM   11515 C CE  . LYS F 2 131 ? -9.059  -8.877  -101.970 1.00 147.31 ? 131 LYS J CE  1 
ATOM   11516 N NZ  . LYS F 2 131 ? -9.590  -10.265 -102.084 1.00 150.04 ? 131 LYS J NZ  1 
ATOM   11517 N N   . GLU F 2 132 ? -12.733 -6.812  -98.334  1.00 151.03 ? 132 GLU J N   1 
ATOM   11518 C CA  . GLU F 2 132 ? -12.239 -6.131  -97.145  1.00 152.74 ? 132 GLU J CA  1 
ATOM   11519 C C   . GLU F 2 132 ? -10.765 -5.782  -97.306  1.00 156.72 ? 132 GLU J C   1 
ATOM   11520 O O   . GLU F 2 132 ? -9.977  -6.574  -97.829  1.00 160.63 ? 132 GLU J O   1 
ATOM   11521 C CB  . GLU F 2 132 ? -12.433 -7.001  -95.903  1.00 149.76 ? 132 GLU J CB  1 
ATOM   11522 C CG  . GLU F 2 132 ? -13.883 -7.268  -95.539  1.00 144.54 ? 132 GLU J CG  1 
ATOM   11523 C CD  . GLU F 2 132 ? -14.023 -8.012  -94.224  1.00 147.65 ? 132 GLU J CD  1 
ATOM   11524 O OE1 . GLU F 2 132 ? -13.021 -8.109  -93.485  1.00 147.97 ? 132 GLU J OE1 1 
ATOM   11525 O OE2 . GLU F 2 132 ? -15.134 -8.500  -93.930  1.00 145.81 ? 132 GLU J OE2 1 
ATOM   11526 N N   . LEU F 2 133 ? -10.395 -4.586  -96.853  1.00 154.99 ? 133 LEU J N   1 
ATOM   11527 C CA  . LEU F 2 133 ? -9.006  -4.151  -96.924  1.00 151.22 ? 133 LEU J CA  1 
ATOM   11528 C C   . LEU F 2 133 ? -8.201  -4.538  -95.691  1.00 149.52 ? 133 LEU J C   1 
ATOM   11529 O O   . LEU F 2 133 ? -7.004  -4.824  -95.807  1.00 148.10 ? 133 LEU J O   1 
ATOM   11530 C CB  . LEU F 2 133 ? -8.936  -2.635  -97.122  1.00 150.68 ? 133 LEU J CB  1 
ATOM   11531 C CG  . LEU F 2 133 ? -9.631  -2.085  -98.368  1.00 153.36 ? 133 LEU J CG  1 
ATOM   11532 C CD1 . LEU F 2 133 ? -9.345  -0.601  -98.539  1.00 148.30 ? 133 LEU J CD1 1 
ATOM   11533 C CD2 . LEU F 2 133 ? -9.201  -2.862  -99.600  1.00 147.32 ? 133 LEU J CD2 1 
ATOM   11534 N N   . GLY F 2 134 ? -8.831  -4.564  -94.518  1.00 156.48 ? 134 GLY J N   1 
ATOM   11535 C CA  . GLY F 2 134 ? -8.145  -4.844  -93.272  1.00 162.96 ? 134 GLY J CA  1 
ATOM   11536 C C   . GLY F 2 134 ? -7.938  -3.640  -92.381  1.00 158.34 ? 134 GLY J C   1 
ATOM   11537 O O   . GLY F 2 134 ? -7.374  -3.790  -91.290  1.00 141.70 ? 134 GLY J O   1 
ATOM   11538 N N   . ASN F 2 135 ? -8.374  -2.453  -92.803  1.00 158.53 ? 135 ASN J N   1 
ATOM   11539 C CA  . ASN F 2 135 ? -8.248  -1.234  -92.014  1.00 157.99 ? 135 ASN J CA  1 
ATOM   11540 C C   . ASN F 2 135 ? -9.602  -0.561  -91.815  1.00 155.06 ? 135 ASN J C   1 
ATOM   11541 O O   . ASN F 2 135 ? -9.694  0.668   -91.772  1.00 156.74 ? 135 ASN J O   1 
ATOM   11542 C CB  . ASN F 2 135 ? -7.259  -0.268  -92.667  1.00 157.37 ? 135 ASN J CB  1 
ATOM   11543 C CG  . ASN F 2 135 ? -7.705  0.179   -94.047  1.00 152.62 ? 135 ASN J CG  1 
ATOM   11544 O OD1 . ASN F 2 135 ? -8.468  -0.515  -94.720  1.00 148.33 ? 135 ASN J OD1 1 
ATOM   11545 N ND2 . ASN F 2 135 ? -7.230  1.343   -94.474  1.00 152.36 ? 135 ASN J ND2 1 
ATOM   11546 N N   . GLY F 2 136 ? -10.662 -1.357  -91.689  1.00 152.80 ? 136 GLY J N   1 
ATOM   11547 C CA  . GLY F 2 136 ? -11.992 -0.800  -91.545  1.00 149.61 ? 136 GLY J CA  1 
ATOM   11548 C C   . GLY F 2 136 ? -12.581 -0.236  -92.815  1.00 147.95 ? 136 GLY J C   1 
ATOM   11549 O O   . GLY F 2 136 ? -13.496 0.589   -92.749  1.00 135.97 ? 136 GLY J O   1 
ATOM   11550 N N   . CYS F 2 137 ? -12.081 -0.656  -93.976  1.00 154.78 ? 137 CYS J N   1 
ATOM   11551 C CA  . CYS F 2 137 ? -12.551 -0.161  -95.260  1.00 152.04 ? 137 CYS J CA  1 
ATOM   11552 C C   . CYS F 2 137 ? -12.889 -1.336  -96.166  1.00 150.67 ? 137 CYS J C   1 
ATOM   11553 O O   . CYS F 2 137 ? -12.324 -2.426  -96.034  1.00 146.88 ? 137 CYS J O   1 
ATOM   11554 C CB  . CYS F 2 137 ? -11.502 0.732   -95.935  1.00 150.33 ? 137 CYS J CB  1 
ATOM   11555 S SG  . CYS F 2 137 ? -10.725 1.939   -94.836  1.00 150.67 ? 137 CYS J SG  1 
ATOM   11556 N N   . PHE F 2 138 ? -13.817 -1.104  -97.091  1.00 152.50 ? 138 PHE J N   1 
ATOM   11557 C CA  . PHE F 2 138 ? -14.262 -2.118  -98.039  1.00 156.46 ? 138 PHE J CA  1 
ATOM   11558 C C   . PHE F 2 138 ? -13.966 -1.653  -99.456  1.00 156.87 ? 138 PHE J C   1 
ATOM   11559 O O   . PHE F 2 138 ? -14.232 -0.497  -99.803  1.00 151.23 ? 138 PHE J O   1 
ATOM   11560 C CB  . PHE F 2 138 ? -15.759 -2.405  -97.890  1.00 153.30 ? 138 PHE J CB  1 
ATOM   11561 C CG  . PHE F 2 138 ? -16.137 -3.019  -96.573  1.00 146.09 ? 138 PHE J CG  1 
ATOM   11562 C CD1 . PHE F 2 138 ? -16.355 -2.225  -95.461  1.00 146.31 ? 138 PHE J CD1 1 
ATOM   11563 C CD2 . PHE F 2 138 ? -16.290 -4.390  -96.452  1.00 139.34 ? 138 PHE J CD2 1 
ATOM   11564 C CE1 . PHE F 2 138 ? -16.707 -2.786  -94.250  1.00 140.66 ? 138 PHE J CE1 1 
ATOM   11565 C CE2 . PHE F 2 138 ? -16.644 -4.958  -95.244  1.00 136.50 ? 138 PHE J CE2 1 
ATOM   11566 C CZ  . PHE F 2 138 ? -16.852 -4.155  -94.141  1.00 138.94 ? 138 PHE J CZ  1 
ATOM   11567 N N   . GLU F 2 139 ? -13.419 -2.552  -100.270 1.00 155.85 ? 139 GLU J N   1 
ATOM   11568 C CA  . GLU F 2 139 ? -13.197 -2.306  -101.689 1.00 156.28 ? 139 GLU J CA  1 
ATOM   11569 C C   . GLU F 2 139 ? -14.229 -3.097  -102.481 1.00 152.90 ? 139 GLU J C   1 
ATOM   11570 O O   . GLU F 2 139 ? -14.227 -4.332  -102.449 1.00 146.28 ? 139 GLU J O   1 
ATOM   11571 C CB  . GLU F 2 139 ? -11.779 -2.699  -102.104 1.00 157.85 ? 139 GLU J CB  1 
ATOM   11572 C CG  . GLU F 2 139 ? -11.472 -2.502  -103.586 1.00 156.85 ? 139 GLU J CG  1 
ATOM   11573 C CD  . GLU F 2 139 ? -11.114 -1.066  -103.942 1.00 152.52 ? 139 GLU J CD  1 
ATOM   11574 O OE1 . GLU F 2 139 ? -11.672 -0.130  -103.332 1.00 151.32 ? 139 GLU J OE1 1 
ATOM   11575 O OE2 . GLU F 2 139 ? -10.263 -0.874  -104.836 1.00 147.61 ? 139 GLU J OE2 1 
ATOM   11576 N N   . PHE F 2 140 ? -15.106 -2.386  -103.184 1.00 156.76 ? 140 PHE J N   1 
ATOM   11577 C CA  . PHE F 2 140 ? -16.167 -3.037  -103.933 1.00 163.02 ? 140 PHE J CA  1 
ATOM   11578 C C   . PHE F 2 140 ? -15.621 -3.724  -105.181 1.00 165.90 ? 140 PHE J C   1 
ATOM   11579 O O   . PHE F 2 140 ? -14.562 -3.375  -105.711 1.00 159.92 ? 140 PHE J O   1 
ATOM   11580 C CB  . PHE F 2 140 ? -17.240 -2.028  -104.339 1.00 164.04 ? 140 PHE J CB  1 
ATOM   11581 C CG  . PHE F 2 140 ? -18.131 -1.604  -103.212 1.00 166.62 ? 140 PHE J CG  1 
ATOM   11582 C CD1 . PHE F 2 140 ? -17.801 -0.516  -102.425 1.00 168.37 ? 140 PHE J CD1 1 
ATOM   11583 C CD2 . PHE F 2 140 ? -19.302 -2.291  -102.944 1.00 162.54 ? 140 PHE J CD2 1 
ATOM   11584 C CE1 . PHE F 2 140 ? -18.621 -0.123  -101.388 1.00 169.59 ? 140 PHE J CE1 1 
ATOM   11585 C CE2 . PHE F 2 140 ? -20.128 -1.901  -101.910 1.00 164.28 ? 140 PHE J CE2 1 
ATOM   11586 C CZ  . PHE F 2 140 ? -19.787 -0.815  -101.130 1.00 170.45 ? 140 PHE J CZ  1 
ATOM   11587 N N   . TYR F 2 141 ? -16.370 -4.723  -105.645 1.00 160.87 ? 141 TYR J N   1 
ATOM   11588 C CA  . TYR F 2 141 ? -16.154 -5.340  -106.949 1.00 148.66 ? 141 TYR J CA  1 
ATOM   11589 C C   . TYR F 2 141 ? -17.125 -4.809  -107.998 1.00 152.88 ? 141 TYR J C   1 
ATOM   11590 O O   . TYR F 2 141 ? -17.574 -5.572  -108.860 1.00 161.82 ? 141 TYR J O   1 
ATOM   11591 C CB  . TYR F 2 141 ? -16.276 -6.861  -106.854 1.00 149.54 ? 141 TYR J CB  1 
ATOM   11592 C CG  . TYR F 2 141 ? -15.149 -7.562  -106.124 1.00 146.89 ? 141 TYR J CG  1 
ATOM   11593 C CD1 . TYR F 2 141 ? -13.927 -6.935  -105.913 1.00 132.72 ? 141 TYR J CD1 1 
ATOM   11594 C CD2 . TYR F 2 141 ? -15.310 -8.859  -105.656 1.00 150.13 ? 141 TYR J CD2 1 
ATOM   11595 C CE1 . TYR F 2 141 ? -12.900 -7.584  -105.247 1.00 130.20 ? 141 TYR J CE1 1 
ATOM   11596 C CE2 . TYR F 2 141 ? -14.294 -9.512  -104.993 1.00 143.59 ? 141 TYR J CE2 1 
ATOM   11597 C CZ  . TYR F 2 141 ? -13.091 -8.873  -104.790 1.00 140.59 ? 141 TYR J CZ  1 
ATOM   11598 O OH  . TYR F 2 141 ? -12.080 -9.530  -104.128 1.00 143.22 ? 141 TYR J OH  1 
ATOM   11599 N N   . HIS F 2 142 ? -17.485 -3.530  -107.921 1.00 147.10 ? 142 HIS J N   1 
ATOM   11600 C CA  . HIS F 2 142 ? -18.411 -2.924  -108.872 1.00 143.20 ? 142 HIS J CA  1 
ATOM   11601 C C   . HIS F 2 142 ? -18.462 -1.424  -108.618 1.00 141.97 ? 142 HIS J C   1 
ATOM   11602 O O   . HIS F 2 142 ? -17.918 -0.920  -107.631 1.00 142.81 ? 142 HIS J O   1 
ATOM   11603 C CB  . HIS F 2 142 ? -19.815 -3.530  -108.771 1.00 146.42 ? 142 HIS J CB  1 
ATOM   11604 C CG  . HIS F 2 142 ? -20.495 -3.270  -107.464 1.00 153.61 ? 142 HIS J CG  1 
ATOM   11605 N ND1 . HIS F 2 142 ? -21.424 -2.266  -107.292 1.00 149.75 ? 142 HIS J ND1 1 
ATOM   11606 C CD2 . HIS F 2 142 ? -20.376 -3.881  -106.262 1.00 156.77 ? 142 HIS J CD2 1 
ATOM   11607 C CE1 . HIS F 2 142 ? -21.851 -2.273  -106.042 1.00 145.97 ? 142 HIS J CE1 1 
ATOM   11608 N NE2 . HIS F 2 142 ? -21.231 -3.244  -105.396 1.00 154.15 ? 142 HIS J NE2 1 
ATOM   11609 N N   . LYS F 2 143 ? -19.130 -0.718  -109.527 1.00 142.68 ? 143 LYS J N   1 
ATOM   11610 C CA  . LYS F 2 143 ? -19.353 0.713   -109.376 1.00 145.97 ? 143 LYS J CA  1 
ATOM   11611 C C   . LYS F 2 143 ? -20.459 0.968   -108.360 1.00 146.95 ? 143 LYS J C   1 
ATOM   11612 O O   . LYS F 2 143 ? -21.434 0.215   -108.280 1.00 144.98 ? 143 LYS J O   1 
ATOM   11613 C CB  . LYS F 2 143 ? -19.725 1.341   -110.720 1.00 138.71 ? 143 LYS J CB  1 
ATOM   11614 C CG  . LYS F 2 143 ? -18.788 0.978   -111.862 1.00 138.19 ? 143 LYS J CG  1 
ATOM   11615 C CD  . LYS F 2 143 ? -17.381 1.495   -111.614 1.00 134.92 ? 143 LYS J CD  1 
ATOM   11616 C CE  . LYS F 2 143 ? -16.450 1.123   -112.758 1.00 132.02 ? 143 LYS J CE  1 
ATOM   11617 N NZ  . LYS F 2 143 ? -16.928 1.663   -114.061 1.00 142.57 ? 143 LYS J NZ  1 
ATOM   11618 N N   . CYS F 2 144 ? -20.303 2.035   -107.580 1.00 152.79 ? 144 CYS J N   1 
ATOM   11619 C CA  . CYS F 2 144 ? -21.286 2.430   -106.578 1.00 157.59 ? 144 CYS J CA  1 
ATOM   11620 C C   . CYS F 2 144 ? -21.716 3.865   -106.842 1.00 155.82 ? 144 CYS J C   1 
ATOM   11621 O O   . CYS F 2 144 ? -20.875 4.769   -106.899 1.00 158.51 ? 144 CYS J O   1 
ATOM   11622 C CB  . CYS F 2 144 ? -20.720 2.295   -105.162 1.00 159.02 ? 144 CYS J CB  1 
ATOM   11623 S SG  . CYS F 2 144 ? -20.690 0.609   -104.510 1.00 156.13 ? 144 CYS J SG  1 
ATOM   11624 N N   . ASP F 2 145 ? -23.020 4.071   -106.995 1.00 153.28 ? 145 ASP J N   1 
ATOM   11625 C CA  . ASP F 2 145 ? -23.570 5.406   -107.153 1.00 152.59 ? 145 ASP J CA  1 
ATOM   11626 C C   . ASP F 2 145 ? -23.579 6.135   -105.813 1.00 148.64 ? 145 ASP J C   1 
ATOM   11627 O O   . ASP F 2 145 ? -23.293 5.563   -104.757 1.00 141.75 ? 145 ASP J O   1 
ATOM   11628 C CB  . ASP F 2 145 ? -24.990 5.343   -107.715 1.00 153.78 ? 145 ASP J CB  1 
ATOM   11629 C CG  . ASP F 2 145 ? -25.059 4.656   -109.064 1.00 148.59 ? 145 ASP J CG  1 
ATOM   11630 O OD1 . ASP F 2 145 ? -24.234 4.980   -109.943 1.00 158.11 ? 145 ASP J OD1 1 
ATOM   11631 O OD2 . ASP F 2 145 ? -25.943 3.791   -109.244 1.00 134.90 ? 145 ASP J OD2 1 
ATOM   11632 N N   . ASN F 2 146 ? -23.912 7.427   -105.863 1.00 149.93 ? 146 ASN J N   1 
ATOM   11633 C CA  . ASN F 2 146 ? -24.244 8.139   -104.636 1.00 152.49 ? 146 ASN J CA  1 
ATOM   11634 C C   . ASN F 2 146 ? -25.567 7.661   -104.053 1.00 156.74 ? 146 ASN J C   1 
ATOM   11635 O O   . ASN F 2 146 ? -25.839 7.911   -102.874 1.00 152.76 ? 146 ASN J O   1 
ATOM   11636 C CB  . ASN F 2 146 ? -24.287 9.647   -104.887 1.00 148.35 ? 146 ASN J CB  1 
ATOM   11637 C CG  . ASN F 2 146 ? -22.908 10.280  -104.864 1.00 148.51 ? 146 ASN J CG  1 
ATOM   11638 O OD1 . ASN F 2 146 ? -21.895 9.597   -105.014 1.00 140.79 ? 146 ASN J OD1 1 
ATOM   11639 N ND2 . ASN F 2 146 ? -22.863 11.594  -104.669 1.00 139.81 ? 146 ASN J ND2 1 
ATOM   11640 N N   . GLU F 2 147 ? -26.393 6.987   -104.858 1.00 160.75 ? 147 GLU J N   1 
ATOM   11641 C CA  . GLU F 2 147 ? -27.578 6.316   -104.337 1.00 156.46 ? 147 GLU J CA  1 
ATOM   11642 C C   . GLU F 2 147 ? -27.222 4.974   -103.709 1.00 155.71 ? 147 GLU J C   1 
ATOM   11643 O O   . GLU F 2 147 ? -27.759 4.618   -102.653 1.00 155.64 ? 147 GLU J O   1 
ATOM   11644 C CB  . GLU F 2 147 ? -28.607 6.129   -105.453 1.00 148.52 ? 147 GLU J CB  1 
ATOM   11645 C CG  . GLU F 2 147 ? -29.764 7.110   -105.398 1.00 140.91 ? 147 GLU J CG  1 
ATOM   11646 C CD  . GLU F 2 147 ? -30.837 6.685   -104.416 1.00 146.46 ? 147 GLU J CD  1 
ATOM   11647 O OE1 . GLU F 2 147 ? -31.755 5.941   -104.821 1.00 147.73 ? 147 GLU J OE1 1 
ATOM   11648 O OE2 . GLU F 2 147 ? -30.757 7.086   -103.236 1.00 154.53 ? 147 GLU J OE2 1 
ATOM   11649 N N   . CYS F 2 148 ? -26.323 4.216   -104.344 1.00 154.28 ? 148 CYS J N   1 
ATOM   11650 C CA  . CYS F 2 148 ? -25.857 2.971   -103.743 1.00 154.50 ? 148 CYS J CA  1 
ATOM   11651 C C   . CYS F 2 148 ? -25.030 3.234   -102.492 1.00 163.51 ? 148 CYS J C   1 
ATOM   11652 O O   . CYS F 2 148 ? -25.066 2.435   -101.549 1.00 162.28 ? 148 CYS J O   1 
ATOM   11653 C CB  . CYS F 2 148 ? -25.047 2.162   -104.756 1.00 148.31 ? 148 CYS J CB  1 
ATOM   11654 S SG  . CYS F 2 148 ? -24.518 0.538   -104.155 1.00 159.93 ? 148 CYS J SG  1 
ATOM   11655 N N   . MET F 2 149 ? -24.273 4.334   -102.467 1.00 163.17 ? 149 MET J N   1 
ATOM   11656 C CA  . MET F 2 149 ? -23.570 4.713   -101.246 1.00 160.80 ? 149 MET J CA  1 
ATOM   11657 C C   . MET F 2 149 ? -24.549 5.038   -100.127 1.00 157.34 ? 149 MET J C   1 
ATOM   11658 O O   . MET F 2 149 ? -24.342 4.637   -98.976  1.00 151.90 ? 149 MET J O   1 
ATOM   11659 C CB  . MET F 2 149 ? -22.643 5.898   -101.511 1.00 154.10 ? 149 MET J CB  1 
ATOM   11660 C CG  . MET F 2 149 ? -21.221 5.476   -101.800 1.00 153.38 ? 149 MET J CG  1 
ATOM   11661 S SD  . MET F 2 149 ? -20.694 4.208   -100.634 1.00 165.25 ? 149 MET J SD  1 
ATOM   11662 C CE  . MET F 2 149 ? -19.874 3.070   -101.741 1.00 146.54 ? 149 MET J CE  1 
ATOM   11663 N N   . GLU F 2 150 ? -25.622 5.765   -100.444 1.00 153.20 ? 150 GLU J N   1 
ATOM   11664 C CA  . GLU F 2 150 ? -26.659 6.018   -99.453  1.00 150.14 ? 150 GLU J CA  1 
ATOM   11665 C C   . GLU F 2 150 ? -27.440 4.756   -99.112  1.00 150.49 ? 150 GLU J C   1 
ATOM   11666 O O   . GLU F 2 150 ? -28.064 4.696   -98.047  1.00 147.13 ? 150 GLU J O   1 
ATOM   11667 C CB  . GLU F 2 150 ? -27.612 7.105   -99.952  1.00 148.37 ? 150 GLU J CB  1 
ATOM   11668 C CG  . GLU F 2 150 ? -28.348 7.837   -98.842  1.00 152.45 ? 150 GLU J CG  1 
ATOM   11669 C CD  . GLU F 2 150 ? -27.432 8.740   -98.037  1.00 156.35 ? 150 GLU J CD  1 
ATOM   11670 O OE1 . GLU F 2 150 ? -26.807 9.641   -98.635  1.00 154.72 ? 150 GLU J OE1 1 
ATOM   11671 O OE2 . GLU F 2 150 ? -27.328 8.543   -96.808  1.00 149.87 ? 150 GLU J OE2 1 
ATOM   11672 N N   . SER F 2 151 ? -27.419 3.750   -99.990  1.00 156.44 ? 151 SER J N   1 
ATOM   11673 C CA  . SER F 2 151 ? -28.122 2.502   -99.712  1.00 150.14 ? 151 SER J CA  1 
ATOM   11674 C C   . SER F 2 151 ? -27.401 1.684   -98.646  1.00 145.27 ? 151 SER J C   1 
ATOM   11675 O O   . SER F 2 151 ? -28.046 1.044   -97.807  1.00 143.43 ? 151 SER J O   1 
ATOM   11676 C CB  . SER F 2 151 ? -28.275 1.692   -100.999 1.00 144.15 ? 151 SER J CB  1 
ATOM   11677 O OG  . SER F 2 151 ? -28.882 0.438   -100.745 1.00 134.24 ? 151 SER J OG  1 
ATOM   11678 N N   . VAL F 2 152 ? -26.066 1.683   -98.669  1.00 143.35 ? 152 VAL J N   1 
ATOM   11679 C CA  . VAL F 2 152 ? -25.307 0.925   -97.679  1.00 142.88 ? 152 VAL J CA  1 
ATOM   11680 C C   . VAL F 2 152 ? -25.484 1.531   -96.291  1.00 140.24 ? 152 VAL J C   1 
ATOM   11681 O O   . VAL F 2 152 ? -25.623 0.807   -95.297  1.00 131.27 ? 152 VAL J O   1 
ATOM   11682 C CB  . VAL F 2 152 ? -23.825 0.848   -98.086  1.00 142.37 ? 152 VAL J CB  1 
ATOM   11683 C CG1 . VAL F 2 152 ? -23.053 -0.027  -97.114  1.00 137.43 ? 152 VAL J CG1 1 
ATOM   11684 C CG2 . VAL F 2 152 ? -23.694 0.312   -99.503  1.00 143.41 ? 152 VAL J CG2 1 
ATOM   11685 N N   . ARG F 2 153 ? -25.474 2.864   -96.197  1.00 140.89 ? 153 ARG J N   1 
ATOM   11686 C CA  . ARG F 2 153 ? -25.771 3.518   -94.926  1.00 140.00 ? 153 ARG J CA  1 
ATOM   11687 C C   . ARG F 2 153 ? -27.196 3.221   -94.481  1.00 143.15 ? 153 ARG J C   1 
ATOM   11688 O O   . ARG F 2 153 ? -27.452 2.990   -93.292  1.00 136.97 ? 153 ARG J O   1 
ATOM   11689 C CB  . ARG F 2 153 ? -25.569 5.029   -95.046  1.00 135.53 ? 153 ARG J CB  1 
ATOM   11690 C CG  . ARG F 2 153 ? -24.391 5.463   -95.899  1.00 139.16 ? 153 ARG J CG  1 
ATOM   11691 C CD  . ARG F 2 153 ? -24.477 6.955   -96.194  1.00 140.87 ? 153 ARG J CD  1 
ATOM   11692 N NE  . ARG F 2 153 ? -23.575 7.369   -97.262  1.00 151.25 ? 153 ARG J NE  1 
ATOM   11693 C CZ  . ARG F 2 153 ? -23.585 8.570   -97.826  1.00 151.23 ? 153 ARG J CZ  1 
ATOM   11694 N NH1 . ARG F 2 153 ? -24.443 9.504   -97.448  1.00 143.54 ? 153 ARG J NH1 1 
ATOM   11695 N NH2 . ARG F 2 153 ? -22.714 8.840   -98.794  1.00 148.40 ? 153 ARG J NH2 1 
ATOM   11696 N N   . ASN F 2 154 ? -28.138 3.230   -95.427  1.00 148.16 ? 154 ASN J N   1 
ATOM   11697 C CA  . ASN F 2 154 ? -29.547 3.030   -95.101  1.00 143.85 ? 154 ASN J CA  1 
ATOM   11698 C C   . ASN F 2 154 ? -29.798 1.633   -94.546  1.00 135.07 ? 154 ASN J C   1 
ATOM   11699 O O   . ASN F 2 154 ? -30.599 1.460   -93.620  1.00 130.27 ? 154 ASN J O   1 
ATOM   11700 C CB  . ASN F 2 154 ? -30.399 3.274   -96.349  1.00 141.41 ? 154 ASN J CB  1 
ATOM   11701 C CG  . ASN F 2 154 ? -31.860 3.528   -96.029  1.00 137.19 ? 154 ASN J CG  1 
ATOM   11702 O OD1 . ASN F 2 154 ? -32.383 3.057   -95.020  1.00 138.85 ? 154 ASN J OD1 1 
ATOM   11703 N ND2 . ASN F 2 154 ? -32.530 4.279   -96.897  1.00 120.94 ? 154 ASN J ND2 1 
ATOM   11704 N N   . GLY F 2 155 ? -29.118 0.630   -95.088  1.00 132.49 ? 155 GLY J N   1 
ATOM   11705 C CA  . GLY F 2 155 ? -29.442 -0.751  -94.807  1.00 134.81 ? 155 GLY J CA  1 
ATOM   11706 C C   . GLY F 2 155 ? -30.337 -1.407  -95.832  1.00 137.73 ? 155 GLY J C   1 
ATOM   11707 O O   . GLY F 2 155 ? -30.874 -2.487  -95.560  1.00 132.13 ? 155 GLY J O   1 
ATOM   11708 N N   . THR F 2 156 ? -30.516 -0.789  -96.997  1.00 142.64 ? 156 THR J N   1 
ATOM   11709 C CA  . THR F 2 156 ? -31.365 -1.301  -98.067  1.00 139.08 ? 156 THR J CA  1 
ATOM   11710 C C   . THR F 2 156 ? -30.539 -1.722  -99.279  1.00 133.54 ? 156 THR J C   1 
ATOM   11711 O O   . THR F 2 156 ? -30.930 -1.497  -100.426 1.00 133.56 ? 156 THR J O   1 
ATOM   11712 C CB  . THR F 2 156 ? -32.407 -0.261  -98.471  1.00 132.42 ? 156 THR J CB  1 
ATOM   11713 O OG1 . THR F 2 156 ? -31.749 0.957   -98.842  1.00 128.62 ? 156 THR J OG1 1 
ATOM   11714 C CG2 . THR F 2 156 ? -33.359 0.017   -97.317  1.00 128.10 ? 156 THR J CG2 1 
ATOM   11715 N N   . TYR F 2 157 ? -29.382 -2.333  -99.037  1.00 132.72 ? 157 TYR J N   1 
ATOM   11716 C CA  . TYR F 2 157 ? -28.505 -2.736  -100.126 1.00 134.86 ? 157 TYR J CA  1 
ATOM   11717 C C   . TYR F 2 157 ? -29.110 -3.896  -100.911 1.00 133.98 ? 157 TYR J C   1 
ATOM   11718 O O   . TYR F 2 157 ? -29.841 -4.731  -100.371 1.00 126.80 ? 157 TYR J O   1 
ATOM   11719 C CB  . TYR F 2 157 ? -27.127 -3.124  -99.587  1.00 137.72 ? 157 TYR J CB  1 
ATOM   11720 C CG  . TYR F 2 157 ? -26.122 -3.461  -100.665 1.00 134.53 ? 157 TYR J CG  1 
ATOM   11721 C CD1 . TYR F 2 157 ? -25.560 -2.465  -101.453 1.00 136.17 ? 157 TYR J CD1 1 
ATOM   11722 C CD2 . TYR F 2 157 ? -25.733 -4.774  -100.892 1.00 133.71 ? 157 TYR J CD2 1 
ATOM   11723 C CE1 . TYR F 2 157 ? -24.640 -2.768  -102.440 1.00 141.65 ? 157 TYR J CE1 1 
ATOM   11724 C CE2 . TYR F 2 157 ? -24.813 -5.088  -101.875 1.00 141.54 ? 157 TYR J CE2 1 
ATOM   11725 C CZ  . TYR F 2 157 ? -24.271 -4.081  -102.646 1.00 144.42 ? 157 TYR J CZ  1 
ATOM   11726 O OH  . TYR F 2 157 ? -23.355 -4.389  -103.626 1.00 139.06 ? 157 TYR J OH  1 
ATOM   11727 N N   . ASP F 2 158 ? -28.796 -3.938  -102.205 1.00 137.47 ? 158 ASP J N   1 
ATOM   11728 C CA  . ASP F 2 158 ? -29.337 -4.928  -103.135 1.00 133.61 ? 158 ASP J CA  1 
ATOM   11729 C C   . ASP F 2 158 ? -28.187 -5.805  -103.622 1.00 136.76 ? 158 ASP J C   1 
ATOM   11730 O O   . ASP F 2 158 ? -27.458 -5.432  -104.546 1.00 142.05 ? 158 ASP J O   1 
ATOM   11731 C CB  . ASP F 2 158 ? -30.048 -4.236  -104.294 1.00 132.31 ? 158 ASP J CB  1 
ATOM   11732 C CG  . ASP F 2 158 ? -30.871 -5.193  -105.136 1.00 135.06 ? 158 ASP J CG  1 
ATOM   11733 O OD1 . ASP F 2 158 ? -30.319 -6.206  -105.616 1.00 136.63 ? 158 ASP J OD1 1 
ATOM   11734 O OD2 . ASP F 2 158 ? -32.080 -4.933  -105.311 1.00 128.31 ? 158 ASP J OD2 1 
ATOM   11735 N N   . TYR F 2 159 ? -28.026 -6.967  -102.992 1.00 134.05 ? 159 TYR J N   1 
ATOM   11736 C CA  . TYR F 2 159 ? -26.959 -7.887  -103.384 1.00 136.90 ? 159 TYR J CA  1 
ATOM   11737 C C   . TYR F 2 159 ? -27.113 -8.454  -104.790 1.00 147.01 ? 159 TYR J C   1 
ATOM   11738 O O   . TYR F 2 159 ? -26.115 -8.473  -105.531 1.00 151.37 ? 159 TYR J O   1 
ATOM   11739 C CB  . TYR F 2 159 ? -26.856 -9.012  -102.350 1.00 138.70 ? 159 TYR J CB  1 
ATOM   11740 C CG  . TYR F 2 159 ? -25.895 -10.120 -102.721 1.00 145.53 ? 159 TYR J CG  1 
ATOM   11741 C CD1 . TYR F 2 159 ? -24.522 -9.924  -102.657 1.00 142.36 ? 159 TYR J CD1 1 
ATOM   11742 C CD2 . TYR F 2 159 ? -26.361 -11.369 -103.112 1.00 142.29 ? 159 TYR J CD2 1 
ATOM   11743 C CE1 . TYR F 2 159 ? -23.639 -10.937 -102.985 1.00 140.10 ? 159 TYR J CE1 1 
ATOM   11744 C CE2 . TYR F 2 159 ? -25.488 -12.387 -103.439 1.00 142.08 ? 159 TYR J CE2 1 
ATOM   11745 C CZ  . TYR F 2 159 ? -24.128 -12.166 -103.374 1.00 141.56 ? 159 TYR J CZ  1 
ATOM   11746 O OH  . TYR F 2 159 ? -23.251 -13.176 -103.699 1.00 137.81 ? 159 TYR J OH  1 
ATOM   11747 N N   . PRO F 2 160 ? -28.283 -8.952  -105.218 1.00 148.68 ? 160 PRO J N   1 
ATOM   11748 C CA  . PRO F 2 160 ? -28.343 -9.614  -106.534 1.00 148.21 ? 160 PRO J CA  1 
ATOM   11749 C C   . PRO F 2 160 ? -27.962 -8.725  -107.706 1.00 148.11 ? 160 PRO J C   1 
ATOM   11750 O O   . PRO F 2 160 ? -27.415 -9.234  -108.692 1.00 146.22 ? 160 PRO J O   1 
ATOM   11751 C CB  . PRO F 2 160 ? -29.806 -10.070 -106.629 1.00 144.01 ? 160 PRO J CB  1 
ATOM   11752 C CG  . PRO F 2 160 ? -30.250 -10.199 -105.225 1.00 140.40 ? 160 PRO J CG  1 
ATOM   11753 C CD  . PRO F 2 160 ? -29.560 -9.091  -104.493 1.00 136.64 ? 160 PRO J CD  1 
ATOM   11754 N N   . GLN F 2 161 ? -28.237 -7.419  -107.635 1.00 145.94 ? 161 GLN J N   1 
ATOM   11755 C CA  . GLN F 2 161 ? -28.004 -6.547  -108.785 1.00 137.82 ? 161 GLN J CA  1 
ATOM   11756 C C   . GLN F 2 161 ? -26.541 -6.559  -109.209 1.00 140.60 ? 161 GLN J C   1 
ATOM   11757 O O   . GLN F 2 161 ? -26.223 -6.788  -110.382 1.00 149.02 ? 161 GLN J O   1 
ATOM   11758 C CB  . GLN F 2 161 ? -28.448 -5.119  -108.467 1.00 125.50 ? 161 GLN J CB  1 
ATOM   11759 C CG  . GLN F 2 161 ? -29.941 -4.882  -108.564 1.00 122.61 ? 161 GLN J CG  1 
ATOM   11760 C CD  . GLN F 2 161 ? -30.283 -3.406  -108.598 1.00 129.25 ? 161 GLN J CD  1 
ATOM   11761 O OE1 . GLN F 2 161 ? -29.456 -2.575  -108.976 1.00 121.99 ? 161 GLN J OE1 1 
ATOM   11762 N NE2 . GLN F 2 161 ? -31.504 -3.070  -108.198 1.00 138.09 ? 161 GLN J NE2 1 
ATOM   11763 N N   . TYR F 2 162 ? -25.636 -6.316  -108.268 1.00 134.14 ? 162 TYR J N   1 
ATOM   11764 C CA  . TYR F 2 162 ? -24.215 -6.231  -108.567 1.00 141.08 ? 162 TYR J CA  1 
ATOM   11765 C C   . TYR F 2 162 ? -23.484 -7.546  -108.339 1.00 153.85 ? 162 TYR J C   1 
ATOM   11766 O O   . TYR F 2 162 ? -22.258 -7.590  -108.485 1.00 155.52 ? 162 TYR J O   1 
ATOM   11767 C CB  . TYR F 2 162 ? -23.575 -5.121  -107.726 1.00 145.67 ? 162 TYR J CB  1 
ATOM   11768 C CG  . TYR F 2 162 ? -24.414 -3.863  -107.656 1.00 144.31 ? 162 TYR J CG  1 
ATOM   11769 C CD1 . TYR F 2 162 ? -24.349 -2.904  -108.659 1.00 145.86 ? 162 TYR J CD1 1 
ATOM   11770 C CD2 . TYR F 2 162 ? -25.276 -3.637  -106.590 1.00 139.48 ? 162 TYR J CD2 1 
ATOM   11771 C CE1 . TYR F 2 162 ? -25.117 -1.754  -108.600 1.00 141.21 ? 162 TYR J CE1 1 
ATOM   11772 C CE2 . TYR F 2 162 ? -26.048 -2.492  -106.523 1.00 132.60 ? 162 TYR J CE2 1 
ATOM   11773 C CZ  . TYR F 2 162 ? -25.964 -1.553  -107.530 1.00 131.77 ? 162 TYR J CZ  1 
ATOM   11774 O OH  . TYR F 2 162 ? -26.731 -0.412  -107.466 1.00 104.62 ? 162 TYR J OH  1 
ATOM   11775 N N   . SER F 2 163 ? -24.203 -8.614  -107.985 1.00 156.36 ? 163 SER J N   1 
ATOM   11776 C CA  . SER F 2 163 ? -23.558 -9.900  -107.740 1.00 160.54 ? 163 SER J CA  1 
ATOM   11777 C C   . SER F 2 163 ? -23.002 -10.492 -109.030 1.00 168.97 ? 163 SER J C   1 
ATOM   11778 O O   . SER F 2 163 ? -21.848 -10.935 -109.075 1.00 170.65 ? 163 SER J O   1 
ATOM   11779 C CB  . SER F 2 163 ? -24.547 -10.864 -107.083 1.00 158.78 ? 163 SER J CB  1 
ATOM   11780 O OG  . SER F 2 163 ? -23.910 -12.072 -106.706 1.00 166.66 ? 163 SER J OG  1 
ATOM   11781 N N   . GLU F 2 164 ? -23.813 -10.513 -110.091 1.00 167.54 ? 164 GLU J N   1 
ATOM   11782 C CA  . GLU F 2 164 ? -23.333 -11.008 -111.377 1.00 169.80 ? 164 GLU J CA  1 
ATOM   11783 C C   . GLU F 2 164 ? -22.269 -10.088 -111.961 1.00 172.54 ? 164 GLU J C   1 
ATOM   11784 O O   . GLU F 2 164 ? -21.367 -10.553 -112.669 1.00 171.08 ? 164 GLU J O   1 
ATOM   11785 C CB  . GLU F 2 164 ? -24.507 -11.169 -112.345 1.00 159.58 ? 164 GLU J CB  1 
ATOM   11786 C CG  . GLU F 2 164 ? -24.208 -12.025 -113.569 1.00 153.03 ? 164 GLU J CG  1 
ATOM   11787 C CD  . GLU F 2 164 ? -25.471 -12.513 -114.259 1.00 148.23 ? 164 GLU J CD  1 
ATOM   11788 O OE1 . GLU F 2 164 ? -26.556 -12.420 -113.649 1.00 143.69 ? 164 GLU J OE1 1 
ATOM   11789 O OE2 . GLU F 2 164 ? -25.378 -12.992 -115.410 1.00 134.98 ? 164 GLU J OE2 1 
ATOM   11790 N N   . GLU F 2 165 ? -22.359 -8.788  -111.678 1.00 169.72 ? 165 GLU J N   1 
ATOM   11791 C CA  . GLU F 2 165 ? -21.319 -7.857  -112.101 1.00 158.62 ? 165 GLU J CA  1 
ATOM   11792 C C   . GLU F 2 165 ? -20.025 -8.085  -111.328 1.00 156.95 ? 165 GLU J C   1 
ATOM   11793 O O   . GLU F 2 165 ? -18.930 -7.960  -111.889 1.00 149.99 ? 165 GLU J O   1 
ATOM   11794 C CB  . GLU F 2 165 ? -21.812 -6.420  -111.925 1.00 147.13 ? 165 GLU J CB  1 
ATOM   11795 C CG  . GLU F 2 165 ? -20.826 -5.345  -112.346 1.00 136.30 ? 165 GLU J CG  1 
ATOM   11796 C CD  . GLU F 2 165 ? -21.453 -3.964  -112.355 1.00 129.31 ? 165 GLU J CD  1 
ATOM   11797 O OE1 . GLU F 2 165 ? -22.699 -3.879  -112.380 1.00 113.71 ? 165 GLU J OE1 1 
ATOM   11798 O OE2 . GLU F 2 165 ? -20.704 -2.965  -112.334 1.00 138.49 ? 165 GLU J OE2 1 
ATOM   11799 N N   . ALA F 2 166 ? -20.132 -8.428  -110.040 1.00 159.93 ? 166 ALA J N   1 
ATOM   11800 C CA  . ALA F 2 166 ? -18.945 -8.591  -109.205 1.00 160.57 ? 166 ALA J CA  1 
ATOM   11801 C C   . ALA F 2 166 ? -18.064 -9.739  -109.681 1.00 166.31 ? 166 ALA J C   1 
ATOM   11802 O O   . ALA F 2 166 ? -16.844 -9.708  -109.476 1.00 164.72 ? 166 ALA J O   1 
ATOM   11803 C CB  . ALA F 2 166 ? -19.353 -8.809  -107.748 1.00 152.60 ? 166 ALA J CB  1 
ATOM   11804 N N   . ARG F 2 167 ? -18.653 -10.761 -110.306 1.00 167.68 ? 167 ARG J N   1 
ATOM   11805 C CA  . ARG F 2 167 ? -17.860 -11.886 -110.788 1.00 166.00 ? 167 ARG J CA  1 
ATOM   11806 C C   . ARG F 2 167 ? -16.966 -11.505 -111.960 1.00 166.19 ? 167 ARG J C   1 
ATOM   11807 O O   . ARG F 2 167 ? -15.978 -12.201 -112.220 1.00 166.92 ? 167 ARG J O   1 
ATOM   11808 C CB  . ARG F 2 167 ? -18.770 -13.047 -111.190 1.00 162.50 ? 167 ARG J CB  1 
ATOM   11809 C CG  . ARG F 2 167 ? -19.790 -13.438 -110.135 1.00 158.91 ? 167 ARG J CG  1 
ATOM   11810 C CD  . ARG F 2 167 ? -20.087 -14.928 -110.190 1.00 156.10 ? 167 ARG J CD  1 
ATOM   11811 N NE  . ARG F 2 167 ? -20.011 -15.453 -111.548 1.00 161.56 ? 167 ARG J NE  1 
ATOM   11812 C CZ  . ARG F 2 167 ? -21.027 -15.487 -112.399 1.00 161.22 ? 167 ARG J CZ  1 
ATOM   11813 N NH1 . ARG F 2 167 ? -22.221 -15.026 -112.069 1.00 162.15 ? 167 ARG J NH1 1 
ATOM   11814 N NH2 . ARG F 2 167 ? -20.839 -15.997 -113.613 1.00 158.19 ? 167 ARG J NH2 1 
ATOM   11815 N N   . LEU F 2 168 ? -17.285 -10.420 -112.669 1.00 168.15 ? 168 LEU J N   1 
ATOM   11816 C CA  . LEU F 2 168 ? -16.465 -9.972  -113.788 1.00 172.20 ? 168 LEU J CA  1 
ATOM   11817 C C   . LEU F 2 168 ? -15.112 -9.432  -113.347 1.00 169.22 ? 168 LEU J C   1 
ATOM   11818 O O   . LEU F 2 168 ? -14.250 -9.196  -114.201 1.00 165.76 ? 168 LEU J O   1 
ATOM   11819 C CB  . LEU F 2 168 ? -17.208 -8.900  -114.588 1.00 168.23 ? 168 LEU J CB  1 
ATOM   11820 C CG  . LEU F 2 168 ? -18.651 -9.202  -115.000 1.00 165.37 ? 168 LEU J CG  1 
ATOM   11821 C CD1 . LEU F 2 168 ? -19.238 -8.034  -115.780 1.00 147.91 ? 168 LEU J CD1 1 
ATOM   11822 C CD2 . LEU F 2 168 ? -18.730 -10.488 -115.808 1.00 164.06 ? 168 LEU J CD2 1 
ATOM   11823 N N   . LYS F 2 169 ? -14.912 -9.213  -112.047 1.00 164.39 ? 169 LYS J N   1 
ATOM   11824 C CA  . LYS F 2 169 ? -13.641 -8.736  -111.524 1.00 162.18 ? 169 LYS J CA  1 
ATOM   11825 C C   . LYS F 2 169 ? -13.072 -9.623  -110.428 1.00 166.84 ? 169 LYS J C   1 
ATOM   11826 O O   . LYS F 2 169 ? -11.926 -9.406  -110.019 1.00 164.49 ? 169 LYS J O   1 
ATOM   11827 C CB  . LYS F 2 169 ? -13.780 -7.304  -110.979 1.00 153.86 ? 169 LYS J CB  1 
ATOM   11828 C CG  . LYS F 2 169 ? -14.655 -6.379  -111.820 1.00 144.09 ? 169 LYS J CG  1 
ATOM   11829 C CD  . LYS F 2 169 ? -16.100 -6.416  -111.348 1.00 141.82 ? 169 LYS J CD  1 
ATOM   11830 C CE  . LYS F 2 169 ? -16.971 -5.393  -112.058 1.00 135.15 ? 169 LYS J CE  1 
ATOM   11831 N NZ  . LYS F 2 169 ? -17.431 -5.871  -113.389 1.00 143.46 ? 169 LYS J NZ  1 
ATOM   11832 N N   . ARG F 2 170 ? -13.828 -10.608 -109.941 1.00 168.19 ? 170 ARG J N   1 
ATOM   11833 C CA  . ARG F 2 170 ? -13.348 -11.491 -108.884 1.00 173.68 ? 170 ARG J CA  1 
ATOM   11834 C C   . ARG F 2 170 ? -12.448 -12.585 -109.447 1.00 180.09 ? 170 ARG J C   1 
ATOM   11835 O O   . ARG F 2 170 ? -11.268 -12.679 -109.095 1.00 175.47 ? 170 ARG J O   1 
ATOM   11836 C CB  . ARG F 2 170 ? -14.542 -12.100 -108.144 1.00 166.53 ? 170 ARG J CB  1 
ATOM   11837 C CG  . ARG F 2 170 ? -14.185 -13.045 -107.012 1.00 159.32 ? 170 ARG J CG  1 
ATOM   11838 C CD  . ARG F 2 170 ? -15.400 -13.867 -106.622 1.00 157.09 ? 170 ARG J CD  1 
ATOM   11839 N NE  . ARG F 2 170 ? -16.609 -13.051 -106.599 1.00 157.41 ? 170 ARG J NE  1 
ATOM   11840 C CZ  . ARG F 2 170 ? -17.842 -13.537 -106.550 1.00 152.28 ? 170 ARG J CZ  1 
ATOM   11841 N NH1 . ARG F 2 170 ? -18.071 -14.840 -106.516 1.00 146.90 ? 170 ARG J NH1 1 
ATOM   11842 N NH2 . ARG F 2 170 ? -18.871 -12.694 -106.540 1.00 147.31 ? 170 ARG J NH2 1 
ATOM   11843 N N   . GLU F 2 171 ? -12.994 -13.421 -110.331 1.00 180.61 ? 171 GLU J N   1 
ATOM   11844 C CA  . GLU F 2 171 ? -12.227 -14.494 -110.947 1.00 177.51 ? 171 GLU J CA  1 
ATOM   11845 C C   . GLU F 2 171 ? -11.521 -14.066 -112.226 1.00 175.73 ? 171 GLU J C   1 
ATOM   11846 O O   . GLU F 2 171 ? -10.521 -14.688 -112.602 1.00 169.26 ? 171 GLU J O   1 
ATOM   11847 C CB  . GLU F 2 171 ? -13.140 -15.690 -111.242 1.00 171.81 ? 171 GLU J CB  1 
ATOM   11848 C CG  . GLU F 2 171 ? -14.413 -15.329 -111.993 1.00 169.80 ? 171 GLU J CG  1 
ATOM   11849 C CD  . GLU F 2 171 ? -15.340 -16.515 -112.173 1.00 162.04 ? 171 GLU J CD  1 
ATOM   11850 O OE1 . GLU F 2 171 ? -14.916 -17.654 -111.882 1.00 157.06 ? 171 GLU J OE1 1 
ATOM   11851 O OE2 . GLU F 2 171 ? -16.495 -16.309 -112.601 1.00 161.37 ? 171 GLU J OE2 1 
ATOM   11852 N N   . GLU F 2 172 ? -12.016 -13.026 -112.901 1.00 176.49 ? 172 GLU J N   1 
ATOM   11853 C CA  . GLU F 2 172 ? -11.357 -12.547 -114.113 1.00 177.65 ? 172 GLU J CA  1 
ATOM   11854 C C   . GLU F 2 172 ? -10.018 -11.895 -113.791 1.00 175.97 ? 172 GLU J C   1 
ATOM   11855 O O   . GLU F 2 172 ? -9.007  -12.172 -114.447 1.00 172.19 ? 172 GLU J O   1 
ATOM   11856 C CB  . GLU F 2 172 ? -12.266 -11.565 -114.852 1.00 174.49 ? 172 GLU J CB  1 
ATOM   11857 C CG  . GLU F 2 172 ? -13.573 -12.159 -115.358 1.00 175.23 ? 172 GLU J CG  1 
ATOM   11858 C CD  . GLU F 2 172 ? -13.381 -13.073 -116.553 1.00 184.77 ? 172 GLU J CD  1 
ATOM   11859 O OE1 . GLU F 2 172 ? -12.944 -14.227 -116.362 1.00 189.03 ? 172 GLU J OE1 1 
ATOM   11860 O OE2 . GLU F 2 172 ? -13.662 -12.632 -117.688 1.00 183.76 ? 172 GLU J OE2 1 
ATOM   11861 N N   . ILE F 2 173 ? -9.991  -11.027 -112.782 1.00 173.84 ? 173 ILE J N   1 
ATOM   11862 C CA  . ILE F 2 173 ? -8.778  -10.302 -112.406 1.00 171.79 ? 173 ILE J CA  1 
ATOM   11863 C C   . ILE F 2 173 ? -7.940  -11.235 -111.537 1.00 169.62 ? 173 ILE J C   1 
ATOM   11864 O O   . ILE F 2 173 ? -8.172  -11.359 -110.333 1.00 163.91 ? 173 ILE J O   1 
ATOM   11865 C CB  . ILE F 2 173 ? -9.096  -8.990  -111.686 1.00 165.94 ? 173 ILE J CB  1 
ATOM   11866 C CG1 . ILE F 2 173 ? -10.073 -8.150  -112.512 1.00 160.00 ? 173 ILE J CG1 1 
ATOM   11867 C CG2 . ILE F 2 173 ? -7.818  -8.210  -111.416 1.00 162.68 ? 173 ILE J CG2 1 
ATOM   11868 C CD1 . ILE F 2 173 ? -9.551  -7.770  -113.881 1.00 156.00 ? 173 ILE J CD1 1 
ATOM   11869 N N   . SER F 2 174 ? -6.960  -11.896 -112.146 1.00 165.42 ? 174 SER J N   1 
ATOM   11870 C CA  . SER F 2 174 ? -6.089  -12.814 -111.423 1.00 157.27 ? 174 SER J CA  1 
ATOM   11871 C C   . SER F 2 174 ? -4.667  -12.269 -111.341 1.00 149.03 ? 174 SER J C   1 
ATOM   11872 O O   . SER F 2 174 ? -3.697  -13.025 -111.402 1.00 146.78 ? 174 SER J O   1 
ATOM   11873 C CB  . SER F 2 174 ? -6.087  -14.191 -112.090 1.00 149.44 ? 174 SER J CB  1 
ATOM   11874 O OG  . SER F 2 174 ? -7.383  -14.765 -112.080 1.00 148.24 ? 174 SER J OG  1 
HETATM 11875 C C1  . GAL G 3 .   ? -64.895 21.030  2.179    1.00 137.68 ? 1   GAL E C1  1 
HETATM 11876 C C2  . GAL G 3 .   ? -63.491 21.625  2.154    1.00 135.40 ? 1   GAL E C2  1 
HETATM 11877 C C3  . GAL G 3 .   ? -62.425 20.522  2.196    1.00 129.27 ? 1   GAL E C3  1 
HETATM 11878 C C4  . GAL G 3 .   ? -62.750 19.407  3.201    1.00 126.58 ? 1   GAL E C4  1 
HETATM 11879 C C5  . GAL G 3 .   ? -64.249 19.069  3.266    1.00 135.09 ? 1   GAL E C5  1 
HETATM 11880 C C6  . GAL G 3 .   ? -64.585 18.221  4.475    1.00 126.90 ? 1   GAL E C6  1 
HETATM 11881 O O1  . GAL G 3 .   ? -65.826 22.046  2.234    1.00 126.18 ? 1   GAL E O1  1 
HETATM 11882 O O2  . GAL G 3 .   ? -63.392 22.389  0.978    1.00 130.40 ? 1   GAL E O2  1 
HETATM 11883 O O3  . GAL G 3 .   ? -61.197 21.117  2.560    1.00 128.94 ? 1   GAL E O3  1 
HETATM 11884 O O4  . GAL G 3 .   ? -62.254 19.805  4.459    1.00 120.70 ? 1   GAL E O4  1 
HETATM 11885 O O5  . GAL G 3 .   ? -65.038 20.235  3.325    1.00 135.07 ? 1   GAL E O5  1 
HETATM 11886 O O6  . GAL G 3 .   ? -65.982 18.112  4.603    1.00 119.57 ? 1   GAL E O6  1 
HETATM 11887 C C1  . NAG G 3 .   ? -60.331 21.615  1.492    1.00 120.40 ? 2   NAG E C1  1 
HETATM 11888 C C2  . NAG G 3 .   ? -59.522 20.470  0.854    1.00 115.87 ? 2   NAG E C2  1 
HETATM 11889 C C3  . NAG G 3 .   ? -58.448 21.106  -0.040   1.00 107.45 ? 2   NAG E C3  1 
HETATM 11890 C C4  . NAG G 3 .   ? -59.052 22.140  -0.997   1.00 116.44 ? 2   NAG E C4  1 
HETATM 11891 C C5  . NAG G 3 .   ? -60.153 23.002  -0.356   1.00 122.91 ? 2   NAG E C5  1 
HETATM 11892 C C6  . NAG G 3 .   ? -60.969 23.786  -1.362   1.00 115.04 ? 2   NAG E C6  1 
HETATM 11893 C C7  . NAG G 3 .   ? -59.034 18.264  1.836    1.00 109.42 ? 2   NAG E C7  1 
HETATM 11894 C C8  . NAG G 3 .   ? -58.370 17.562  2.995    1.00 110.49 ? 2   NAG E C8  1 
HETATM 11895 N N2  . NAG G 3 .   ? -58.959 19.608  1.861    1.00 115.86 ? 2   NAG E N2  1 
HETATM 11896 O O3  . NAG G 3 .   ? -57.813 20.109  -0.800   1.00 106.07 ? 2   NAG E O3  1 
HETATM 11897 O O4  . NAG G 3 .   ? -57.985 22.942  -1.453   1.00 109.47 ? 2   NAG E O4  1 
HETATM 11898 O O5  . NAG G 3 .   ? -61.029 22.199  0.411    1.00 126.65 ? 2   NAG E O5  1 
HETATM 11899 O O6  . NAG G 3 .   ? -60.116 24.595  -2.137   1.00 114.24 ? 2   NAG E O6  1 
HETATM 11900 O O7  . NAG G 3 .   ? -59.595 17.639  0.948    1.00 107.39 ? 2   NAG E O7  1 
HETATM 11901 C C1  . GAL G 3 .   ? -56.572 19.647  -0.221   1.00 90.70  ? 3   GAL E C1  1 
HETATM 11902 C C2  . GAL G 3 .   ? -56.154 18.440  -1.061   1.00 74.68  ? 3   GAL E C2  1 
HETATM 11903 C C3  . GAL G 3 .   ? -54.798 17.900  -0.617   1.00 79.67  ? 3   GAL E C3  1 
HETATM 11904 C C4  . GAL G 3 .   ? -53.760 19.018  -0.574   1.00 76.83  ? 3   GAL E C4  1 
HETATM 11905 C C5  . GAL G 3 .   ? -54.335 20.125  0.316    1.00 79.52  ? 3   GAL E C5  1 
HETATM 11906 C C6  . GAL G 3 .   ? -53.365 21.264  0.556    1.00 73.19  ? 3   GAL E C6  1 
HETATM 11907 O O2  . GAL G 3 .   ? -57.151 17.459  -0.940   1.00 77.68  ? 3   GAL E O2  1 
HETATM 11908 O O3  . GAL G 3 .   ? -54.500 16.897  -1.553   1.00 70.44  ? 3   GAL E O3  1 
HETATM 11909 O O4  . GAL G 3 .   ? -53.518 19.448  -1.892   1.00 68.62  ? 3   GAL E O4  1 
HETATM 11910 O O5  . GAL G 3 .   ? -55.540 20.613  -0.246   1.00 87.32  ? 3   GAL E O5  1 
HETATM 11911 O O6  . GAL G 3 .   ? -53.320 22.096  -0.577   1.00 78.71  ? 3   GAL E O6  1 
HETATM 11912 C C1  . SIA G 3 .   ? -53.965 14.654  -2.138   1.00 82.72  ? 4   SIA E C1  1 
HETATM 11913 C C2  . SIA G 3 .   ? -53.982 15.699  -0.942   1.00 71.12  ? 4   SIA E C2  1 
HETATM 11914 C C3  . SIA G 3 .   ? -54.692 15.117  0.288    1.00 72.88  ? 4   SIA E C3  1 
HETATM 11915 C C4  . SIA G 3 .   ? -54.008 13.835  0.770    1.00 62.36  ? 4   SIA E C4  1 
HETATM 11916 C C5  . SIA G 3 .   ? -52.592 14.178  1.238    1.00 67.98  ? 4   SIA E C5  1 
HETATM 11917 C C6  . SIA G 3 .   ? -51.830 14.940  0.123    1.00 62.58  ? 4   SIA E C6  1 
HETATM 11918 C C7  . SIA G 3 .   ? -50.589 15.685  0.673    1.00 71.82  ? 4   SIA E C7  1 
HETATM 11919 C C8  . SIA G 3 .   ? -49.921 16.508  -0.446   1.00 61.84  ? 4   SIA E C8  1 
HETATM 11920 C C9  . SIA G 3 .   ? -48.459 16.759  -0.116   1.00 58.64  ? 4   SIA E C9  1 
HETATM 11921 C C10 . SIA G 3 .   ? -50.888 12.919  2.561    1.00 53.53  ? 4   SIA E C10 1 
HETATM 11922 C C11 . SIA G 3 .   ? -50.180 11.575  2.709    1.00 49.35  ? 4   SIA E C11 1 
HETATM 11923 N N5  . SIA G 3 .   ? -51.810 12.986  1.562    1.00 58.90  ? 4   SIA E N5  1 
HETATM 11924 O O1A . SIA G 3 .   ? -55.108 14.154  -2.336   1.00 83.22  ? 4   SIA E O1A 1 
HETATM 11925 O O1B . SIA G 3 .   ? -52.889 14.453  -2.750   1.00 74.12  ? 4   SIA E O1B 1 
HETATM 11926 O O4  . SIA G 3 .   ? -54.699 13.197  1.858    1.00 70.65  ? 4   SIA E O4  1 
HETATM 11927 O O6  . SIA G 3 .   ? -52.600 15.962  -0.506   1.00 68.07  ? 4   SIA E O6  1 
HETATM 11928 O O7  . SIA G 3 .   ? -50.938 16.477  1.804    1.00 64.41  ? 4   SIA E O7  1 
HETATM 11929 O O8  . SIA G 3 .   ? -50.074 15.829  -1.692   1.00 59.66  ? 4   SIA E O8  1 
HETATM 11930 O O9  . SIA G 3 .   ? -47.953 17.794  -0.959   1.00 59.84  ? 4   SIA E O9  1 
HETATM 11931 O O10 . SIA G 3 .   ? -50.615 13.854  3.311    1.00 65.99  ? 4   SIA E O10 1 
HETATM 11932 C C1  . GLC H 4 .   ? -9.080  -4.457  25.592   1.00 162.25 ? 1   GLC F C1  1 
HETATM 11933 C C2  . GLC H 4 .   ? -10.345 -5.198  25.192   1.00 166.35 ? 1   GLC F C2  1 
HETATM 11934 C C3  . GLC H 4 .   ? -10.903 -4.728  23.855   1.00 154.57 ? 1   GLC F C3  1 
HETATM 11935 C C4  . GLC H 4 .   ? -10.687 -3.249  23.526   1.00 153.02 ? 1   GLC F C4  1 
HETATM 11936 C C5  . GLC H 4 .   ? -9.494  -2.614  24.244   1.00 152.45 ? 1   GLC F C5  1 
HETATM 11937 C C6  . GLC H 4 .   ? -9.617  -1.095  24.267   1.00 150.75 ? 1   GLC F C6  1 
HETATM 11938 O O1  . GLC H 4 .   ? -8.697  -4.845  26.892   1.00 162.16 ? 1   GLC F O1  1 
HETATM 11939 O O2  . GLC H 4 .   ? -10.054 -6.573  25.084   1.00 171.08 ? 1   GLC F O2  1 
HETATM 11940 O O3  . GLC H 4 .   ? -12.291 -4.992  23.846   1.00 144.59 ? 1   GLC F O3  1 
HETATM 11941 O O4  . GLC H 4 .   ? -10.424 -3.145  22.142   1.00 151.01 ? 1   GLC F O4  1 
HETATM 11942 O O5  . GLC H 4 .   ? -9.360  -3.080  25.568   1.00 154.68 ? 1   GLC F O5  1 
HETATM 11943 O O6  . GLC H 4 .   ? -9.482  -0.594  22.956   1.00 145.32 ? 1   GLC F O6  1 
HETATM 11944 C C1  . GAL H 4 .   ? -11.619 -3.080  21.334   1.00 133.32 ? 2   GAL F C1  1 
HETATM 11945 C C2  . GAL H 4 .   ? -11.202 -2.416  20.019   1.00 121.72 ? 2   GAL F C2  1 
HETATM 11946 C C3  . GAL H 4 .   ? -12.244 -2.580  18.910   1.00 122.09 ? 2   GAL F C3  1 
HETATM 11947 C C4  . GAL H 4 .   ? -12.774 -4.011  18.832   1.00 128.66 ? 2   GAL F C4  1 
HETATM 11948 C C5  . GAL H 4 .   ? -13.247 -4.423  20.223   1.00 128.90 ? 2   GAL F C5  1 
HETATM 11949 C C6  . GAL H 4 .   ? -13.796 -5.833  20.234   1.00 128.06 ? 2   GAL F C6  1 
HETATM 11950 O O2  . GAL H 4 .   ? -10.963 -1.056  20.286   1.00 120.60 ? 2   GAL F O2  1 
HETATM 11951 O O3  . GAL H 4 .   ? -11.597 -2.179  17.724   1.00 114.61 ? 2   GAL F O3  1 
HETATM 11952 O O4  . GAL H 4 .   ? -11.747 -4.842  18.345   1.00 127.69 ? 2   GAL F O4  1 
HETATM 11953 O O5  . GAL H 4 .   ? -12.152 -4.366  21.105   1.00 139.08 ? 2   GAL F O5  1 
HETATM 11954 O O6  . GAL H 4 .   ? -14.775 -5.950  21.237   1.00 128.73 ? 2   GAL F O6  1 
HETATM 11955 C C1  . NAG H 4 .   ? -12.500 -1.552  16.789   1.00 98.41  ? 3   NAG F C1  1 
HETATM 11956 C C2  . NAG H 4 .   ? -11.645 -1.020  15.628   1.00 96.32  ? 3   NAG F C2  1 
HETATM 11957 C C3  . NAG H 4 .   ? -12.502 -0.512  14.468   1.00 90.18  ? 3   NAG F C3  1 
HETATM 11958 C C4  . NAG H 4 .   ? -13.584 -1.522  14.104   1.00 94.11  ? 3   NAG F C4  1 
HETATM 11959 C C5  . NAG H 4 .   ? -14.363 -1.906  15.363   1.00 109.94 ? 3   NAG F C5  1 
HETATM 11960 C C6  . NAG H 4 .   ? -15.465 -2.913  15.116   1.00 112.95 ? 3   NAG F C6  1 
HETATM 11961 C C7  . NAG H 4 .   ? -9.475  -0.212  16.463   1.00 96.76  ? 3   NAG F C7  1 
HETATM 11962 C C8  . NAG H 4 .   ? -8.712  1.011   16.909   1.00 79.47  ? 3   NAG F C8  1 
HETATM 11963 N N2  . NAG H 4 .   ? -10.748 0.009   16.086   1.00 93.07  ? 3   NAG F N2  1 
HETATM 11964 O O3  . NAG H 4 .   ? -11.635 -0.298  13.387   1.00 83.10  ? 3   NAG F O3  1 
HETATM 11965 O O4  . NAG H 4 .   ? -14.415 -0.927  13.134   1.00 96.13  ? 3   NAG F O4  1 
HETATM 11966 O O5  . NAG H 4 .   ? -13.456 -2.457  16.293   1.00 101.21 ? 3   NAG F O5  1 
HETATM 11967 O O6  . NAG H 4 .   ? -14.902 -4.169  14.820   1.00 119.67 ? 3   NAG F O6  1 
HETATM 11968 O O7  . NAG H 4 .   ? -8.956  -1.318  16.454   1.00 112.50 ? 3   NAG F O7  1 
HETATM 11969 C C1  . GAL H 4 .   ? -11.705 1.070   12.939   1.00 65.60  ? 4   GAL F C1  1 
HETATM 11970 C C2  . GAL H 4 .   ? -10.743 1.189   11.757   1.00 71.06  ? 4   GAL F C2  1 
HETATM 11971 C C3  . GAL H 4 .   ? -10.844 2.552   11.071   1.00 55.35  ? 4   GAL F C3  1 
HETATM 11972 C C4  . GAL H 4 .   ? -12.298 2.957   10.807   1.00 59.33  ? 4   GAL F C4  1 
HETATM 11973 C C5  . GAL H 4 .   ? -13.135 2.742   12.076   1.00 64.77  ? 4   GAL F C5  1 
HETATM 11974 C C6  . GAL H 4 .   ? -14.604 3.025   11.847   1.00 63.44  ? 4   GAL F C6  1 
HETATM 11975 O O2  . GAL H 4 .   ? -9.441  0.961   12.235   1.00 66.29  ? 4   GAL F O2  1 
HETATM 11976 O O3  . GAL H 4 .   ? -10.093 2.395   9.892    1.00 64.10  ? 4   GAL F O3  1 
HETATM 11977 O O4  . GAL H 4 .   ? -12.781 2.214   9.714    1.00 59.91  ? 4   GAL F O4  1 
HETATM 11978 O O5  . GAL H 4 .   ? -13.009 1.412   12.533   1.00 67.49  ? 4   GAL F O5  1 
HETATM 11979 O O6  . GAL H 4 .   ? -15.294 2.925   13.070   1.00 80.15  ? 4   GAL F O6  1 
HETATM 11980 C C1  . SIA H 4 .   ? -8.648  3.179   8.140    1.00 74.14  ? 5   SIA F C1  1 
HETATM 11981 C C2  . SIA H 4 .   ? -9.273  3.534   9.557    1.00 54.74  ? 5   SIA F C2  1 
HETATM 11982 C C3  . SIA H 4 .   ? -8.182  3.907   10.571   1.00 56.45  ? 5   SIA F C3  1 
HETATM 11983 C C4  . SIA H 4 .   ? -7.362  5.115   10.106   1.00 59.75  ? 5   SIA F C4  1 
HETATM 11984 C C5  . SIA H 4 .   ? -8.294  6.322   9.983    1.00 53.40  ? 5   SIA F C5  1 
HETATM 11985 C C6  . SIA H 4 .   ? -9.481  5.966   9.058    1.00 59.15  ? 5   SIA F C6  1 
HETATM 11986 C C7  . SIA H 4 .   ? -10.612 7.017   9.114    1.00 57.69  ? 5   SIA F C7  1 
HETATM 11987 C C8  . SIA H 4 .   ? -11.826 6.526   8.302    1.00 60.45  ? 5   SIA F C8  1 
HETATM 11988 C C9  . SIA H 4 .   ? -12.783 7.677   8.047    1.00 48.53  ? 5   SIA F C9  1 
HETATM 11989 C C10 . SIA H 4 .   ? -7.835  8.762   9.811    1.00 52.06  ? 5   SIA F C10 1 
HETATM 11990 C C11 . SIA H 4 .   ? -7.068  9.823   9.029    1.00 45.41  ? 5   SIA F C11 1 
HETATM 11991 N N5  . SIA H 4 .   ? -7.642  7.486   9.389    1.00 65.18  ? 5   SIA F N5  1 
HETATM 11992 O O1A . SIA H 4 .   ? -7.677  2.377   8.242    1.00 62.78  ? 5   SIA F O1A 1 
HETATM 11993 O O1B . SIA H 4 .   ? -9.150  3.685   7.107    1.00 65.16  ? 5   SIA F O1B 1 
HETATM 11994 O O4  . SIA H 4 .   ? -6.296  5.459   11.009   1.00 56.16  ? 5   SIA F O4  1 
HETATM 11995 O O6  . SIA H 4 .   ? -10.108 4.737   9.411    1.00 64.60  ? 5   SIA F O6  1 
HETATM 11996 O O7  . SIA H 4 .   ? -10.930 7.332   10.465   1.00 57.35  ? 5   SIA F O7  1 
HETATM 11997 O O8  . SIA H 4 .   ? -11.380 5.940   7.079    1.00 56.30  ? 5   SIA F O8  1 
HETATM 11998 O O9  . SIA H 4 .   ? -13.942 7.190   7.373    1.00 46.74  ? 5   SIA F O9  1 
HETATM 11999 O O10 . SIA H 4 .   ? -8.572  9.070   10.748   1.00 57.12  ? 5   SIA F O10 1 
HETATM 12000 C C1  . NAG I 5 .   ? -0.635  35.062  -11.493  1.00 52.80  ? 1   NAG G C1  1 
HETATM 12001 C C2  . NAG I 5 .   ? -1.827  36.027  -11.502  1.00 51.76  ? 1   NAG G C2  1 
HETATM 12002 C C3  . NAG I 5 .   ? -1.737  36.932  -12.728  1.00 54.50  ? 1   NAG G C3  1 
HETATM 12003 C C4  . NAG I 5 .   ? -0.393  37.640  -12.817  1.00 57.11  ? 1   NAG G C4  1 
HETATM 12004 C C5  . NAG I 5 .   ? 0.747   36.628  -12.670  1.00 55.79  ? 1   NAG G C5  1 
HETATM 12005 C C6  . NAG I 5 .   ? 2.104   37.294  -12.583  1.00 53.99  ? 1   NAG G C6  1 
HETATM 12006 C C7  . NAG I 5 .   ? -4.065  35.491  -10.619  1.00 56.28  ? 1   NAG G C7  1 
HETATM 12007 C C8  . NAG I 5 .   ? -5.325  34.711  -10.898  1.00 50.94  ? 1   NAG G C8  1 
HETATM 12008 N N2  . NAG I 5 .   ? -3.101  35.363  -11.549  1.00 55.65  ? 1   NAG G N2  1 
HETATM 12009 O O3  . NAG I 5 .   ? -2.806  37.840  -12.675  1.00 73.70  ? 1   NAG G O3  1 
HETATM 12010 O O4  . NAG I 5 .   ? -0.356  38.236  -14.093  1.00 73.45  ? 1   NAG G O4  1 
HETATM 12011 O O5  . NAG I 5 .   ? 0.554   35.824  -11.520  1.00 48.18  ? 1   NAG G O5  1 
HETATM 12012 O O6  . NAG I 5 .   ? 3.043   36.436  -11.981  1.00 64.87  ? 1   NAG G O6  1 
HETATM 12013 O O7  . NAG I 5 .   ? -3.948  36.174  -9.611   1.00 58.29  ? 1   NAG G O7  1 
HETATM 12014 C C1  . NAG I 5 .   ? -0.408  39.672  -13.994  1.00 72.33  ? 2   NAG G C1  1 
HETATM 12015 C C2  . NAG I 5 .   ? 0.015   40.237  -15.358  1.00 77.82  ? 2   NAG G C2  1 
HETATM 12016 C C3  . NAG I 5 .   ? -0.168  41.753  -15.409  1.00 88.50  ? 2   NAG G C3  1 
HETATM 12017 C C4  . NAG I 5 .   ? -1.560  42.152  -14.930  1.00 102.38 ? 2   NAG G C4  1 
HETATM 12018 C C5  . NAG I 5 .   ? -1.810  41.524  -13.555  1.00 97.72  ? 2   NAG G C5  1 
HETATM 12019 C C6  . NAG I 5 .   ? -3.152  41.874  -12.945  1.00 76.87  ? 2   NAG G C6  1 
HETATM 12020 C C7  . NAG I 5 .   ? 1.772   38.715  -16.176  1.00 88.96  ? 2   NAG G C7  1 
HETATM 12021 C C8  . NAG I 5 .   ? 3.259   38.571  -16.384  1.00 82.22  ? 2   NAG G C8  1 
HETATM 12022 N N2  . NAG I 5 .   ? 1.382   39.886  -15.641  1.00 79.73  ? 2   NAG G N2  1 
HETATM 12023 O O3  . NAG I 5 .   ? 0.073   42.168  -16.729  1.00 95.11  ? 2   NAG G O3  1 
HETATM 12024 O O4  . NAG I 5 .   ? -1.605  43.560  -14.880  1.00 106.13 ? 2   NAG G O4  1 
HETATM 12025 O O5  . NAG I 5 .   ? -1.707  40.118  -13.674  1.00 88.15  ? 2   NAG G O5  1 
HETATM 12026 O O6  . NAG I 5 .   ? -4.149  41.879  -13.940  1.00 90.79  ? 2   NAG G O6  1 
HETATM 12027 O O7  . NAG I 5 .   ? 0.993   37.821  -16.477  1.00 96.56  ? 2   NAG G O7  1 
HETATM 12028 C C1  . GLC J 4 .   ? -11.739 58.863  1.009    1.00 108.63 ? 1   GLC H C1  1 
HETATM 12029 C C2  . GLC J 4 .   ? -10.299 58.402  0.839    1.00 105.17 ? 1   GLC H C2  1 
HETATM 12030 C C3  . GLC J 4 .   ? -10.207 57.303  -0.213   1.00 110.19 ? 1   GLC H C3  1 
HETATM 12031 C C4  . GLC J 4 .   ? -11.275 56.222  -0.037   1.00 113.53 ? 1   GLC H C4  1 
HETATM 12032 C C5  . GLC J 4 .   ? -12.635 56.791  0.370    1.00 110.07 ? 1   GLC H C5  1 
HETATM 12033 C C6  . GLC J 4 .   ? -13.565 55.680  0.845    1.00 104.14 ? 1   GLC H C6  1 
HETATM 12034 O O1  . GLC J 4 .   ? -11.808 59.861  2.002    1.00 112.17 ? 1   GLC H O1  1 
HETATM 12035 O O2  . GLC J 4 .   ? -9.494  59.495  0.453    1.00 98.99  ? 1   GLC H O2  1 
HETATM 12036 O O3  . GLC J 4 .   ? -8.927  56.713  -0.143   1.00 98.58  ? 1   GLC H O3  1 
HETATM 12037 O O4  . GLC J 4 .   ? -11.433 55.541  -1.264   1.00 109.41 ? 1   GLC H O4  1 
HETATM 12038 O O5  . GLC J 4 .   ? -12.517 57.754  1.397    1.00 107.26 ? 1   GLC H O5  1 
HETATM 12039 O O6  . GLC J 4 .   ? -14.723 56.246  1.417    1.00 103.50 ? 1   GLC H O6  1 
HETATM 12040 C C1  . GAL J 4 .   ? -10.900 54.201  -1.190   1.00 98.13  ? 2   GAL H C1  1 
HETATM 12041 C C2  . GAL J 4 .   ? -11.448 53.429  -2.395   1.00 98.12  ? 2   GAL H C2  1 
HETATM 12042 C C3  . GAL J 4 .   ? -10.754 52.076  -2.579   1.00 102.64 ? 2   GAL H C3  1 
HETATM 12043 C C4  . GAL J 4 .   ? -9.234  52.177  -2.455   1.00 107.46 ? 2   GAL H C4  1 
HETATM 12044 C C5  . GAL J 4 .   ? -8.900  52.939  -1.171   1.00 107.59 ? 2   GAL H C5  1 
HETATM 12045 C C6  . GAL J 4 .   ? -7.408  53.105  -0.978   1.00 99.90  ? 2   GAL H C6  1 
HETATM 12046 O O2  . GAL J 4 .   ? -12.830 53.257  -2.201   1.00 85.20  ? 2   GAL H O2  1 
HETATM 12047 O O3  . GAL J 4 .   ? -11.157 51.605  -3.844   1.00 105.09 ? 2   GAL H O3  1 
HETATM 12048 O O4  . GAL J 4 .   ? -8.735  52.820  -3.603   1.00 110.21 ? 2   GAL H O4  1 
HETATM 12049 O O5  . GAL J 4 .   ? -9.491  54.219  -1.218   1.00 98.94  ? 2   GAL H O5  1 
HETATM 12050 O O6  . GAL J 4 .   ? -7.129  53.246  0.393    1.00 84.45  ? 2   GAL H O6  1 
HETATM 12051 C C1  . NAG J 4 .   ? -11.302 50.171  -3.868   1.00 95.66  ? 3   NAG H C1  1 
HETATM 12052 C C2  . NAG J 4 .   ? -12.320 49.838  -4.967   1.00 91.14  ? 3   NAG H C2  1 
HETATM 12053 C C3  . NAG J 4 .   ? -12.428 48.334  -5.220   1.00 89.40  ? 3   NAG H C3  1 
HETATM 12054 C C4  . NAG J 4 .   ? -11.042 47.727  -5.396   1.00 82.13  ? 3   NAG H C4  1 
HETATM 12055 C C5  . NAG J 4 .   ? -10.150 48.118  -4.214   1.00 88.98  ? 3   NAG H C5  1 
HETATM 12056 C C6  . NAG J 4 .   ? -8.744  47.571  -4.320   1.00 86.63  ? 3   NAG H C6  1 
HETATM 12057 C C7  . NAG J 4 .   ? -14.309 51.186  -5.498   1.00 85.36  ? 3   NAG H C7  1 
HETATM 12058 C C8  . NAG J 4 .   ? -15.634 51.676  -4.968   1.00 70.14  ? 3   NAG H C8  1 
HETATM 12059 N N2  . NAG J 4 .   ? -13.608 50.403  -4.656   1.00 87.07  ? 3   NAG H N2  1 
HETATM 12060 O O3  . NAG J 4 .   ? -13.185 48.173  -6.388   1.00 84.36  ? 3   NAG H O3  1 
HETATM 12061 O O4  . NAG J 4 .   ? -11.195 46.330  -5.504   1.00 90.07  ? 3   NAG H O4  1 
HETATM 12062 O O5  . NAG J 4 .   ? -10.078 49.529  -4.138   1.00 96.34  ? 3   NAG H O5  1 
HETATM 12063 O O6  . NAG J 4 .   ? -8.220  47.862  -5.594   1.00 92.71  ? 3   NAG H O6  1 
HETATM 12064 O O7  . NAG J 4 .   ? -13.914 51.489  -6.615   1.00 80.82  ? 3   NAG H O7  1 
HETATM 12065 C C1  . GAL J 4 .   ? -14.388 47.421  -6.136   1.00 73.06  ? 4   GAL H C1  1 
HETATM 12066 C C2  . GAL J 4 .   ? -15.095 47.281  -7.482   1.00 79.01  ? 4   GAL H C2  1 
HETATM 12067 C C3  . GAL J 4 .   ? -16.358 46.432  -7.348   1.00 64.54  ? 4   GAL H C3  1 
HETATM 12068 C C4  . GAL J 4 .   ? -16.057 45.101  -6.652   1.00 63.46  ? 4   GAL H C4  1 
HETATM 12069 C C5  . GAL J 4 .   ? -15.246 45.343  -5.369   1.00 58.43  ? 4   GAL H C5  1 
HETATM 12070 C C6  . GAL J 4 .   ? -14.757 44.046  -4.759   1.00 66.69  ? 4   GAL H C6  1 
HETATM 12071 O O2  . GAL J 4 .   ? -15.390 48.570  -7.963   1.00 66.11  ? 4   GAL H O2  1 
HETATM 12072 O O3  . GAL J 4 .   ? -16.801 46.274  -8.674   1.00 61.35  ? 4   GAL H O3  1 
HETATM 12073 O O4  . GAL J 4 .   ? -15.378 44.270  -7.566   1.00 59.10  ? 4   GAL H O4  1 
HETATM 12074 O O5  . GAL J 4 .   ? -14.107 46.141  -5.621   1.00 75.18  ? 4   GAL H O5  1 
HETATM 12075 O O6  . GAL J 4 .   ? -15.444 43.792  -3.558   1.00 71.17  ? 4   GAL H O6  1 
HETATM 12076 C C1  . SIA J 4 .   ? -18.456 46.187  -10.394  1.00 63.77  ? 5   SIA H C1  1 
HETATM 12077 C C2  . SIA J 4 .   ? -18.231 46.385  -8.836   1.00 61.90  ? 5   SIA H C2  1 
HETATM 12078 C C3  . SIA J 4 .   ? -18.904 47.670  -8.334   1.00 63.91  ? 5   SIA H C3  1 
HETATM 12079 C C4  . SIA J 4 .   ? -20.415 47.650  -8.576   1.00 53.68  ? 5   SIA H C4  1 
HETATM 12080 C C5  . SIA J 4 .   ? -21.019 46.503  -7.761   1.00 57.90  ? 5   SIA H C5  1 
HETATM 12081 C C6  . SIA J 4 .   ? -20.311 45.172  -8.121   1.00 52.14  ? 5   SIA H C6  1 
HETATM 12082 C C7  . SIA J 4 .   ? -20.592 44.069  -7.072   1.00 54.63  ? 5   SIA H C7  1 
HETATM 12083 C C8  . SIA J 4 .   ? -19.769 42.794  -7.361   1.00 57.00  ? 5   SIA H C8  1 
HETATM 12084 C C9  . SIA J 4 .   ? -20.483 41.578  -6.794   1.00 56.33  ? 5   SIA H C9  1 
HETATM 12085 C C10 . SIA J 4 .   ? -23.349 46.020  -7.023   1.00 56.71  ? 5   SIA H C10 1 
HETATM 12086 C C11 . SIA J 4 .   ? -24.797 45.872  -7.483   1.00 49.09  ? 5   SIA H C11 1 
HETATM 12087 N N5  . SIA J 4 .   ? -22.453 46.329  -7.998   1.00 49.08  ? 5   SIA H N5  1 
HETATM 12088 O O1A . SIA J 4 .   ? -18.208 47.244  -11.039  1.00 76.98  ? 5   SIA H O1A 1 
HETATM 12089 O O1B . SIA J 4 .   ? -18.827 45.068  -10.819  1.00 66.86  ? 5   SIA H O1B 1 
HETATM 12090 O O4  . SIA J 4 .   ? -21.068 48.874  -8.190   1.00 66.64  ? 5   SIA H O4  1 
HETATM 12091 O O6  . SIA J 4 .   ? -18.892 45.282  -8.123   1.00 63.28  ? 5   SIA H O6  1 
HETATM 12092 O O7  . SIA J 4 .   ? -20.356 44.570  -5.762   1.00 57.12  ? 5   SIA H O7  1 
HETATM 12093 O O8  . SIA J 4 .   ? -19.527 42.662  -8.762   1.00 52.48  ? 5   SIA H O8  1 
HETATM 12094 O O9  . SIA J 4 .   ? -19.538 40.544  -6.519   1.00 58.85  ? 5   SIA H O9  1 
HETATM 12095 O O10 . SIA J 4 .   ? -23.048 45.859  -5.842   1.00 61.67  ? 5   SIA H O10 1 
HETATM 12096 C C1  . NAG K 6 .   ? -24.778 -9.435  3.734    1.00 73.64  ? 401 NAG A C1  1 
HETATM 12097 C C2  . NAG K 6 .   ? -23.614 -8.527  4.171    1.00 71.69  ? 401 NAG A C2  1 
HETATM 12098 C C3  . NAG K 6 .   ? -22.274 -9.239  3.982    1.00 78.54  ? 401 NAG A C3  1 
HETATM 12099 C C4  . NAG K 6 .   ? -22.286 -10.595 4.666    1.00 78.95  ? 401 NAG A C4  1 
HETATM 12100 C C5  . NAG K 6 .   ? -23.466 -11.394 4.113    1.00 83.41  ? 401 NAG A C5  1 
HETATM 12101 C C6  . NAG K 6 .   ? -23.564 -12.786 4.698    1.00 74.11  ? 401 NAG A C6  1 
HETATM 12102 C C7  . NAG K 6 .   ? -23.396 -6.069  3.971    1.00 74.52  ? 401 NAG A C7  1 
HETATM 12103 C C8  . NAG K 6 .   ? -23.239 -6.024  5.473    1.00 75.51  ? 401 NAG A C8  1 
HETATM 12104 N N2  . NAG K 6 .   ? -23.578 -7.292  3.434    1.00 71.06  ? 401 NAG A N2  1 
HETATM 12105 O O3  . NAG K 6 .   ? -21.254 -8.414  4.481    1.00 91.58  ? 401 NAG A O3  1 
HETATM 12106 O O4  . NAG K 6 .   ? -21.051 -11.217 4.392    1.00 91.45  ? 401 NAG A O4  1 
HETATM 12107 O O5  . NAG K 6 .   ? -24.663 -10.687 4.379    1.00 74.89  ? 401 NAG A O5  1 
HETATM 12108 O O6  . NAG K 6 .   ? -22.299 -13.407 4.641    1.00 85.17  ? 401 NAG A O6  1 
HETATM 12109 O O7  . NAG K 6 .   ? -23.360 -5.048  3.302    1.00 81.84  ? 401 NAG A O7  1 
HETATM 12110 C C1  . NAG L 6 .   ? -52.986 30.155  -15.625  1.00 71.03  ? 401 NAG I C1  1 
HETATM 12111 C C2  . NAG L 6 .   ? -53.212 29.006  -14.629  1.00 67.14  ? 401 NAG I C2  1 
HETATM 12112 C C3  . NAG L 6 .   ? -54.263 28.040  -15.174  1.00 79.55  ? 401 NAG I C3  1 
HETATM 12113 C C4  . NAG L 6 .   ? -55.543 28.780  -15.525  1.00 84.58  ? 401 NAG I C4  1 
HETATM 12114 C C5  . NAG L 6 .   ? -55.205 29.903  -16.507  1.00 85.37  ? 401 NAG I C5  1 
HETATM 12115 C C6  . NAG L 6 .   ? -56.400 30.754  -16.868  1.00 69.26  ? 401 NAG I C6  1 
HETATM 12116 C C7  . NAG L 6 .   ? -51.501 28.076  -13.129  1.00 66.98  ? 401 NAG I C7  1 
HETATM 12117 C C8  . NAG L 6 .   ? -50.251 27.233  -13.081  1.00 66.05  ? 401 NAG I C8  1 
HETATM 12118 N N2  . NAG L 6 .   ? -52.018 28.254  -14.358  1.00 63.47  ? 401 NAG I N2  1 
HETATM 12119 O O3  . NAG L 6 .   ? -54.484 27.038  -14.217  1.00 71.62  ? 401 NAG I O3  1 
HETATM 12120 O O4  . NAG L 6 .   ? -56.425 27.838  -16.089  1.00 90.05  ? 401 NAG I O4  1 
HETATM 12121 O O5  . NAG L 6 .   ? -54.229 30.749  -15.933  1.00 79.81  ? 401 NAG I O5  1 
HETATM 12122 O O6  . NAG L 6 .   ? -56.560 31.762  -15.898  1.00 81.07  ? 401 NAG I O6  1 
HETATM 12123 O O7  . NAG L 6 .   ? -51.990 28.559  -12.118  1.00 61.57  ? 401 NAG I O7  1 
HETATM 12124 O O   . HOH M 7 .   ? -37.501 -11.447 -42.786  1.00 86.86  ? 501 HOH A O   1 
HETATM 12125 O O   . HOH M 7 .   ? -49.511 -3.888  -28.368  1.00 60.07  ? 502 HOH A O   1 
HETATM 12126 O O   . HOH M 7 .   ? -42.471 3.558   -33.643  1.00 54.25  ? 503 HOH A O   1 
HETATM 12127 O O   . HOH M 7 .   ? -41.747 5.876   -20.858  1.00 60.17  ? 504 HOH A O   1 
HETATM 12128 O O   . HOH M 7 .   ? -44.737 3.790   18.028   1.00 67.74  ? 505 HOH A O   1 
HETATM 12129 O O   . HOH M 7 .   ? -54.748 3.611   2.751    1.00 64.62  ? 506 HOH A O   1 
HETATM 12130 O O   . HOH M 7 .   ? -31.410 18.568  5.018    1.00 66.86  ? 507 HOH A O   1 
HETATM 12131 O O   . HOH M 7 .   ? -43.980 7.699   16.425   1.00 66.46  ? 508 HOH A O   1 
HETATM 12132 O O   . HOH M 7 .   ? -36.567 23.403  1.006    1.00 61.61  ? 509 HOH A O   1 
HETATM 12133 O O   . HOH M 7 .   ? -40.415 2.361   -32.025  1.00 54.37  ? 510 HOH A O   1 
HETATM 12134 O O   . HOH M 7 .   ? -35.059 -1.794  -62.564  1.00 73.31  ? 511 HOH A O   1 
HETATM 12135 O O   . HOH M 7 .   ? -29.463 5.818   -11.561  1.00 62.52  ? 512 HOH A O   1 
HETATM 12136 O O   . HOH M 7 .   ? -44.731 14.839  -13.306  1.00 67.29  ? 513 HOH A O   1 
HETATM 12137 O O   . HOH M 7 .   ? -26.794 0.707   -9.655   1.00 56.57  ? 514 HOH A O   1 
HETATM 12138 O O   . HOH M 7 .   ? -34.505 15.362  -5.377   1.00 55.67  ? 515 HOH A O   1 
HETATM 12139 O O   . HOH M 7 .   ? -39.744 10.739  -15.015  1.00 66.47  ? 516 HOH A O   1 
HETATM 12140 O O   . HOH M 7 .   ? -27.829 -8.147  -27.163  1.00 61.78  ? 517 HOH A O   1 
HETATM 12141 O O   . HOH M 7 .   ? -32.384 -2.587  9.741    1.00 66.08  ? 518 HOH A O   1 
HETATM 12142 O O   . HOH M 7 .   ? -33.750 17.054  -3.521   1.00 59.86  ? 519 HOH A O   1 
HETATM 12143 O O   . HOH M 7 .   ? -24.063 8.294   -5.267   1.00 58.93  ? 520 HOH A O   1 
HETATM 12144 O O   . HOH M 7 .   ? -31.470 -7.484  5.729    1.00 67.48  ? 521 HOH A O   1 
HETATM 12145 O O   . HOH M 7 .   ? -56.386 0.685   -16.625  1.00 72.96  ? 522 HOH A O   1 
HETATM 12146 O O   . HOH M 7 .   ? -23.053 -1.846  -6.905   1.00 60.23  ? 523 HOH A O   1 
HETATM 12147 O O   . HOH M 7 .   ? -31.079 8.420   -18.518  1.00 47.16  ? 524 HOH A O   1 
HETATM 12148 O O   . HOH M 7 .   ? -31.218 6.825   -9.672   1.00 54.70  ? 525 HOH A O   1 
HETATM 12149 O O   . HOH M 7 .   ? -26.488 12.811  -3.152   1.00 51.69  ? 526 HOH A O   1 
HETATM 12150 O O   . HOH M 7 .   ? -28.852 11.531  -6.379   1.00 76.46  ? 527 HOH A O   1 
HETATM 12151 O O   . HOH M 7 .   ? -46.825 -8.817  -22.374  1.00 67.37  ? 528 HOH A O   1 
HETATM 12152 O O   . HOH M 7 .   ? -25.723 10.523  -5.190   1.00 60.56  ? 529 HOH A O   1 
HETATM 12153 O O   . HOH M 7 .   ? -35.900 -1.258  -60.051  1.00 69.37  ? 530 HOH A O   1 
HETATM 12154 O O   . HOH M 7 .   ? -29.350 6.757   -7.760   1.00 55.95  ? 531 HOH A O   1 
HETATM 12155 O O   . HOH M 7 .   ? -33.947 13.558  -10.052  1.00 63.29  ? 532 HOH A O   1 
HETATM 12156 O O   . HOH M 7 .   ? -31.605 18.301  -3.334   1.00 64.93  ? 533 HOH A O   1 
HETATM 12157 O O   . HOH M 7 .   ? -30.747 -1.526  -38.398  1.00 53.16  ? 534 HOH A O   1 
HETATM 12158 O O   . HOH M 7 .   ? -29.204 -3.277  -39.627  1.00 61.46  ? 535 HOH A O   1 
HETATM 12159 O O   . HOH M 7 .   ? -30.158 14.000  -6.610   1.00 54.81  ? 536 HOH A O   1 
HETATM 12160 O O   . HOH N 7 .   ? -28.838 -2.067  -31.596  1.00 52.74  ? 201 HOH B O   1 
HETATM 12161 O O   . HOH N 7 .   ? -31.080 4.048   -41.943  1.00 54.82  ? 202 HOH B O   1 
HETATM 12162 O O   . HOH N 7 .   ? -32.745 10.129  -33.646  1.00 56.26  ? 203 HOH B O   1 
HETATM 12163 O O   . HOH N 7 .   ? -30.138 -21.342 -56.418  1.00 67.76  ? 204 HOH B O   1 
HETATM 12164 O O   . HOH N 7 .   ? -33.522 9.133   -39.103  1.00 64.04  ? 205 HOH B O   1 
HETATM 12165 O O   . HOH N 7 .   ? -34.550 9.812   -29.300  1.00 56.42  ? 206 HOH B O   1 
HETATM 12166 O O   . HOH N 7 .   ? -38.813 0.333   -32.421  1.00 55.09  ? 207 HOH B O   1 
HETATM 12167 O O   . HOH N 7 .   ? -34.774 11.802  -34.946  1.00 67.98  ? 208 HOH B O   1 
HETATM 12168 O O   . HOH N 7 .   ? -32.794 9.054   -31.110  1.00 59.36  ? 209 HOH B O   1 
HETATM 12169 O O   . HOH O 7 .   ? -10.011 35.896  5.013    1.00 66.63  ? 401 HOH C O   1 
HETATM 12170 O O   . HOH O 7 .   ? -9.560  3.047   -15.728  1.00 60.14  ? 402 HOH C O   1 
HETATM 12171 O O   . HOH O 7 .   ? -13.124 30.631  -0.979   1.00 54.40  ? 403 HOH C O   1 
HETATM 12172 O O   . HOH O 7 .   ? -0.599  11.483  1.328    1.00 44.87  ? 404 HOH C O   1 
HETATM 12173 O O   . HOH O 7 .   ? 0.650   -4.734  -22.127  1.00 67.37  ? 405 HOH C O   1 
HETATM 12174 O O   . HOH O 7 .   ? -7.709  27.854  -15.491  1.00 48.74  ? 406 HOH C O   1 
HETATM 12175 O O   . HOH O 7 .   ? -0.382  23.378  -21.845  1.00 46.79  ? 407 HOH C O   1 
HETATM 12176 O O   . HOH O 7 .   ? -4.775  23.580  14.740   1.00 54.32  ? 408 HOH C O   1 
HETATM 12177 O O   . HOH O 7 .   ? -15.992 -1.255  -40.857  1.00 54.25  ? 409 HOH C O   1 
HETATM 12178 O O   . HOH O 7 .   ? 3.215   30.060  -8.215   1.00 60.69  ? 410 HOH C O   1 
HETATM 12179 O O   . HOH O 7 .   ? -2.265  24.001  16.064   1.00 61.06  ? 411 HOH C O   1 
HETATM 12180 O O   . HOH O 7 .   ? -9.695  24.999  -18.014  1.00 60.36  ? 412 HOH C O   1 
HETATM 12181 O O   . HOH O 7 .   ? 1.156   30.467  -6.102   1.00 50.31  ? 413 HOH C O   1 
HETATM 12182 O O   . HOH O 7 .   ? 6.075   23.838  -23.179  1.00 75.57  ? 414 HOH C O   1 
HETATM 12183 O O   . HOH O 7 .   ? -15.170 30.709  -11.552  1.00 55.59  ? 415 HOH C O   1 
HETATM 12184 O O   . HOH O 7 .   ? -16.297 12.241  -7.720   1.00 48.91  ? 416 HOH C O   1 
HETATM 12185 O O   . HOH O 7 .   ? -9.147  30.678  -0.739   1.00 52.10  ? 417 HOH C O   1 
HETATM 12186 O O   . HOH O 7 .   ? 2.140   12.101  -28.061  1.00 53.38  ? 418 HOH C O   1 
HETATM 12187 O O   . HOH O 7 .   ? -4.262  -2.029  -16.109  1.00 63.40  ? 419 HOH C O   1 
HETATM 12188 O O   . HOH O 7 .   ? -24.149 14.881  5.885    1.00 50.16  ? 420 HOH C O   1 
HETATM 12189 O O   . HOH O 7 .   ? -16.708 11.540  -17.974  1.00 48.20  ? 421 HOH C O   1 
HETATM 12190 O O   . HOH O 7 .   ? -10.078 27.440  -17.364  1.00 57.90  ? 422 HOH C O   1 
HETATM 12191 O O   . HOH O 7 .   ? -1.446  -4.733  -20.792  1.00 59.01  ? 423 HOH C O   1 
HETATM 12192 O O   . HOH O 7 .   ? -11.881 24.109  14.722   1.00 61.98  ? 424 HOH C O   1 
HETATM 12193 O O   . HOH O 7 .   ? -17.856 24.983  -11.278  1.00 62.67  ? 425 HOH C O   1 
HETATM 12194 O O   . HOH O 7 .   ? -13.729 -5.024  -0.569   1.00 62.30  ? 426 HOH C O   1 
HETATM 12195 O O   . HOH O 7 .   ? -13.992 17.139  -11.842  1.00 53.04  ? 427 HOH C O   1 
HETATM 12196 O O   . HOH O 7 .   ? -2.891  31.969  -0.453   1.00 53.04  ? 428 HOH C O   1 
HETATM 12197 O O   . HOH O 7 .   ? -12.649 29.018  -3.155   1.00 48.92  ? 429 HOH C O   1 
HETATM 12198 O O   . HOH O 7 .   ? -10.338 29.511  11.422   1.00 61.09  ? 430 HOH C O   1 
HETATM 12199 O O   . HOH O 7 .   ? -6.711  -7.695  -20.114  1.00 74.67  ? 431 HOH C O   1 
HETATM 12200 O O   . HOH O 7 .   ? -20.449 18.097  7.512    1.00 57.27  ? 432 HOH C O   1 
HETATM 12201 O O   . HOH O 7 .   ? -20.561 22.686  -6.806   1.00 52.27  ? 433 HOH C O   1 
HETATM 12202 O O   . HOH O 7 .   ? -18.075 0.612   10.624   1.00 73.53  ? 434 HOH C O   1 
HETATM 12203 O O   . HOH O 7 .   ? -20.878 10.348  -4.359   1.00 66.27  ? 435 HOH C O   1 
HETATM 12204 O O   . HOH O 7 .   ? -9.541  14.325  -32.992  1.00 56.22  ? 436 HOH C O   1 
HETATM 12205 O O   . HOH O 7 .   ? -13.641 0.371   -40.582  1.00 49.46  ? 437 HOH C O   1 
HETATM 12206 O O   . HOH O 7 .   ? -14.500 19.973  -10.945  1.00 58.05  ? 438 HOH C O   1 
HETATM 12207 O O   . HOH O 7 .   ? -5.924  -9.551  -26.757  1.00 64.41  ? 439 HOH C O   1 
HETATM 12208 O O   . HOH O 7 .   ? -27.543 5.835   4.947    1.00 57.69  ? 440 HOH C O   1 
HETATM 12209 O O   . HOH O 7 .   ? -11.038 22.277  -16.975  1.00 56.17  ? 441 HOH C O   1 
HETATM 12210 O O   . HOH O 7 .   ? -19.103 22.875  -9.966   1.00 70.72  ? 442 HOH C O   1 
HETATM 12211 O O   . HOH O 7 .   ? -22.796 23.044  -6.282   1.00 62.48  ? 443 HOH C O   1 
HETATM 12212 O O   . HOH O 7 .   ? -6.505  13.192  15.703   1.00 63.10  ? 444 HOH C O   1 
HETATM 12213 O O   . HOH O 7 .   ? -1.413  4.277   11.307   1.00 63.27  ? 445 HOH C O   1 
HETATM 12214 O O   . HOH P 7 .   ? -26.902 8.887   -20.384  1.00 50.82  ? 201 HOH D O   1 
HETATM 12215 O O   . HOH P 7 .   ? -17.016 -0.785  -38.398  1.00 54.98  ? 202 HOH D O   1 
HETATM 12216 O O   . HOH P 7 .   ? -20.219 0.877   -28.600  1.00 57.46  ? 203 HOH D O   1 
HETATM 12217 O O   . HOH P 7 .   ? -18.267 2.116   -24.335  1.00 55.16  ? 204 HOH D O   1 
HETATM 12218 O O   . HOH Q 7 .   ? -14.571 35.527  -5.281   1.00 47.33  ? 501 HOH I O   1 
HETATM 12219 O O   . HOH Q 7 .   ? -37.135 46.672  1.461    1.00 62.02  ? 502 HOH I O   1 
HETATM 12220 O O   . HOH Q 7 .   ? -30.727 46.953  -8.157   1.00 55.62  ? 503 HOH I O   1 
HETATM 12221 O O   . HOH Q 7 .   ? -11.377 34.020  -33.178  1.00 61.67  ? 504 HOH I O   1 
HETATM 12222 O O   . HOH Q 7 .   ? -36.387 38.052  3.700    1.00 58.84  ? 505 HOH I O   1 
HETATM 12223 O O   . HOH Q 7 .   ? -31.922 21.237  -27.972  1.00 57.84  ? 506 HOH I O   1 
HETATM 12224 O O   . HOH Q 7 .   ? -25.461 28.123  -14.922  1.00 46.17  ? 507 HOH I O   1 
HETATM 12225 O O   . HOH Q 7 .   ? -17.771 26.556  -39.732  1.00 57.96  ? 508 HOH I O   1 
HETATM 12226 O O   . HOH Q 7 .   ? -40.723 18.362  -11.169  1.00 58.13  ? 509 HOH I O   1 
HETATM 12227 O O   . HOH Q 7 .   ? -17.129 40.675  -8.207   1.00 47.39  ? 510 HOH I O   1 
HETATM 12228 O O   . HOH Q 7 .   ? -21.824 29.621  -0.110   1.00 57.56  ? 511 HOH I O   1 
HETATM 12229 O O   . HOH Q 7 .   ? -29.516 28.313  1.015    1.00 62.57  ? 512 HOH I O   1 
HETATM 12230 O O   . HOH Q 7 .   ? -26.053 33.097  1.038    1.00 52.75  ? 513 HOH I O   1 
HETATM 12231 O O   . HOH Q 7 .   ? -16.694 35.075  3.664    1.00 65.46  ? 514 HOH I O   1 
HETATM 12232 O O   . HOH Q 7 .   ? -25.529 23.813  -29.881  1.00 50.86  ? 515 HOH I O   1 
HETATM 12233 O O   . HOH Q 7 .   ? -19.188 41.349  -23.553  1.00 66.68  ? 516 HOH I O   1 
HETATM 12234 O O   . HOH Q 7 .   ? -13.865 34.677  -34.259  1.00 66.79  ? 517 HOH I O   1 
HETATM 12235 O O   . HOH Q 7 .   ? -42.342 21.057  -10.744  1.00 59.68  ? 518 HOH I O   1 
HETATM 12236 O O   . HOH Q 7 .   ? -26.431 21.677  -23.195  1.00 47.96  ? 519 HOH I O   1 
HETATM 12237 O O   . HOH Q 7 .   ? -40.768 28.576  -6.241   1.00 60.48  ? 520 HOH I O   1 
HETATM 12238 O O   . HOH Q 7 .   ? -14.343 41.396  -7.518   1.00 51.05  ? 521 HOH I O   1 
HETATM 12239 O O   . HOH Q 7 .   ? -15.657 31.190  -43.381  1.00 78.71  ? 522 HOH I O   1 
HETATM 12240 O O   . HOH Q 7 .   ? -36.104 20.642  -11.479  1.00 60.83  ? 523 HOH I O   1 
HETATM 12241 O O   . HOH Q 7 .   ? -30.071 34.351  6.569    1.00 68.02  ? 524 HOH I O   1 
HETATM 12242 O O   . HOH Q 7 .   ? -29.319 18.515  -55.316  1.00 68.20  ? 525 HOH I O   1 
HETATM 12243 O O   . HOH Q 7 .   ? -22.249 13.969  -46.953  1.00 57.31  ? 526 HOH I O   1 
HETATM 12244 O O   . HOH Q 7 .   ? -37.835 23.670  -20.871  1.00 59.45  ? 527 HOH I O   1 
HETATM 12245 O O   . HOH Q 7 .   ? -10.670 38.825  -18.262  1.00 58.57  ? 528 HOH I O   1 
HETATM 12246 O O   . HOH Q 7 .   ? -25.310 25.808  -14.118  1.00 50.07  ? 529 HOH I O   1 
HETATM 12247 O O   . HOH Q 7 .   ? -25.839 26.701  -6.866   1.00 59.45  ? 530 HOH I O   1 
HETATM 12248 O O   . HOH Q 7 .   ? -24.490 48.452  4.306    1.00 76.23  ? 531 HOH I O   1 
HETATM 12249 O O   . HOH Q 7 .   ? -10.879 42.028  -6.245   1.00 63.05  ? 532 HOH I O   1 
HETATM 12250 O O   . HOH Q 7 .   ? -34.595 36.089  5.129    1.00 59.87  ? 533 HOH I O   1 
HETATM 12251 O O   . HOH Q 7 .   ? -33.377 25.131  -15.352  1.00 64.38  ? 534 HOH I O   1 
HETATM 12252 O O   . HOH Q 7 .   ? -33.437 21.326  -10.596  1.00 57.38  ? 535 HOH I O   1 
HETATM 12253 O O   . HOH Q 7 .   ? -24.993 16.010  -44.583  1.00 61.92  ? 536 HOH I O   1 
HETATM 12254 O O   . HOH Q 7 .   ? -19.453 31.648  -27.213  1.00 61.96  ? 537 HOH I O   1 
HETATM 12255 O O   . HOH Q 7 .   ? -15.644 25.826  -38.234  1.00 64.78  ? 538 HOH I O   1 
HETATM 12256 O O   . HOH Q 7 .   ? -23.873 49.368  -4.879   1.00 61.87  ? 539 HOH I O   1 
HETATM 12257 O O   . HOH R 7 .   ? -18.622 19.605  -31.278  1.00 60.99  ? 201 HOH J O   1 
HETATM 12258 O O   . HOH R 7 .   ? -24.956 18.943  -36.176  1.00 62.86  ? 202 HOH J O   1 
HETATM 12259 O O   . HOH R 7 .   ? -11.626 13.268  -32.077  1.00 56.16  ? 203 HOH J O   1 
HETATM 12260 O O   . HOH R 7 .   ? -32.551 13.398  -58.055  1.00 69.13  ? 204 HOH J O   1 
HETATM 12261 O O   . HOH R 7 .   ? -22.308 24.744  -40.015  1.00 59.40  ? 205 HOH J O   1 
HETATM 12262 O O   . HOH R 7 .   ? -25.492 14.992  -23.377  1.00 58.53  ? 206 HOH J O   1 
HETATM 12263 O O   . HOH R 7 .   ? -11.755 20.499  -19.220  1.00 67.56  ? 207 HOH J O   1 
HETATM 12264 O O   . HOH R 7 .   ? -25.136 14.507  -42.065  1.00 62.82  ? 208 HOH J O   1 
# 
