data_9DAP
# 
_entry.id   9DAP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DAP         pdb_00009dap 10.2210/pdb9dap/pdb 
WWPDB D_1000287736 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-19 ? 
2 'Structure model' 1 1 2025-03-12 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_citation.journal_volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DAP 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              vprasad@bcm.edu 
_pdbx_contact_author.name_first         B.V.V 
_pdbx_contact_author.name_last          Prasad 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1172-2071 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Pham, S.H.'     1 0000-0001-6642-8796 
'Neetu, N.'      2 ?                   
'Sankaran, B.'   3 0000-0002-3266-8131 
'Prasad, B.V.V.' 4 0000-0002-1172-2071 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Virol. 
_citation.journal_id_ASTM           JOVIAM 
_citation.journal_id_CSD            0825 
_citation.journal_id_ISSN           1098-5514 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            99 
_citation.language                  ? 
_citation.page_first                e0175724 
_citation.page_last                 e0175724 
_citation.title                     
'Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1128/jvi.01757-24 
_citation.pdbx_database_id_PubMed   39873493 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Pham, S.'       1  ?                   
primary 'Zhao, B.'       2  ?                   
primary 'Neetu, N.'      3  ?                   
primary 'Sankaran, B.'   4  ?                   
primary 'Patil, K.'      5  ?                   
primary 'Ramani, S.'     6  0000-0001-5631-8534 
primary 'Song, Y.'       7  ?                   
primary 'Estes, M.K.'    8  0000-0002-4813-4249 
primary 'Palzkill, T.'   9  ?                   
primary 'Prasad, B.V.V.' 10 0000-0002-1172-2071 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Genome polyprotein' 19347.287 1 ? ? ? ? 
2 non-polymer syn 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
600.678   1 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQGTQEFFGVPTKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEAMLE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQGTQEFFGVPTKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEAMLE
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
_pdbx_entity_nonpoly.comp_id     AG7 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   PRO n 
1 3   PRO n 
1 4   SER n 
1 5   ILE n 
1 6   TRP n 
1 7   SER n 
1 8   ARG n 
1 9   ILE n 
1 10  VAL n 
1 11  ASN n 
1 12  PHE n 
1 13  GLY n 
1 14  SER n 
1 15  GLY n 
1 16  TRP n 
1 17  GLY n 
1 18  PHE n 
1 19  TRP n 
1 20  VAL n 
1 21  SER n 
1 22  PRO n 
1 23  SER n 
1 24  LEU n 
1 25  PHE n 
1 26  ILE n 
1 27  THR n 
1 28  SER n 
1 29  THR n 
1 30  HIS n 
1 31  VAL n 
1 32  ILE n 
1 33  PRO n 
1 34  GLN n 
1 35  GLY n 
1 36  THR n 
1 37  GLN n 
1 38  GLU n 
1 39  PHE n 
1 40  PHE n 
1 41  GLY n 
1 42  VAL n 
1 43  PRO n 
1 44  THR n 
1 45  LYS n 
1 46  GLN n 
1 47  ILE n 
1 48  GLN n 
1 49  ILE n 
1 50  HIS n 
1 51  LYS n 
1 52  SER n 
1 53  GLY n 
1 54  GLU n 
1 55  PHE n 
1 56  CYS n 
1 57  ARG n 
1 58  LEU n 
1 59  ARG n 
1 60  PHE n 
1 61  PRO n 
1 62  LYS n 
1 63  PRO n 
1 64  ILE n 
1 65  ARG n 
1 66  THR n 
1 67  ASP n 
1 68  VAL n 
1 69  THR n 
1 70  GLY n 
1 71  MET n 
1 72  ILE n 
1 73  LEU n 
1 74  GLU n 
1 75  GLU n 
1 76  GLY n 
1 77  ALA n 
1 78  PRO n 
1 79  GLU n 
1 80  GLY n 
1 81  THR n 
1 82  VAL n 
1 83  ALA n 
1 84  THR n 
1 85  LEU n 
1 86  LEU n 
1 87  ILE n 
1 88  LYS n 
1 89  ARG n 
1 90  PRO n 
1 91  THR n 
1 92  GLY n 
1 93  GLU n 
1 94  LEU n 
1 95  MET n 
1 96  PRO n 
1 97  LEU n 
1 98  ALA n 
1 99  ALA n 
1 100 ARG n 
1 101 MET n 
1 102 GLY n 
1 103 THR n 
1 104 HIS n 
1 105 ALA n 
1 106 THR n 
1 107 MET n 
1 108 LYS n 
1 109 ILE n 
1 110 GLN n 
1 111 GLY n 
1 112 ARG n 
1 113 THR n 
1 114 VAL n 
1 115 GLY n 
1 116 GLY n 
1 117 GLN n 
1 118 MET n 
1 119 GLY n 
1 120 MET n 
1 121 LEU n 
1 122 LEU n 
1 123 THR n 
1 124 GLY n 
1 125 SER n 
1 126 ASN n 
1 127 ALA n 
1 128 LYS n 
1 129 SER n 
1 130 MET n 
1 131 ASP n 
1 132 LEU n 
1 133 GLY n 
1 134 THR n 
1 135 THR n 
1 136 PRO n 
1 137 GLY n 
1 138 ASP n 
1 139 CYS n 
1 140 GLY n 
1 141 CYS n 
1 142 PRO n 
1 143 TYR n 
1 144 ILE n 
1 145 TYR n 
1 146 LYS n 
1 147 ARG n 
1 148 GLY n 
1 149 ASN n 
1 150 ASP n 
1 151 TYR n 
1 152 VAL n 
1 153 VAL n 
1 154 ILE n 
1 155 GLY n 
1 156 VAL n 
1 157 HIS n 
1 158 THR n 
1 159 ALA n 
1 160 ALA n 
1 161 ALA n 
1 162 ARG n 
1 163 GLY n 
1 164 GLY n 
1 165 ASN n 
1 166 THR n 
1 167 VAL n 
1 168 ILE n 
1 169 CYS n 
1 170 ALA n 
1 171 THR n 
1 172 GLN n 
1 173 GLY n 
1 174 SER n 
1 175 GLU n 
1 176 GLY n 
1 177 GLU n 
1 178 ALA n 
1 179 MET n 
1 180 LEU n 
1 181 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   181 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      Norovirus 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     142786 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli B' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     37762 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
AG7 non-polymer         . 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
'RUPINTRIVIR, bound form' 'C31 H41 F N4 O7' 600.678 
ALA 'L-peptide linking' y ALANINE ?                         'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE ?                         'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                         'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                         'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE ?                         'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                         'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                         'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE ?                         'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE ?                         'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE ?                         'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE ?                         'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE ?                         'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE ?                         'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                         'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE ?                         'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE ?                         'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE ?                         'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                         'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE ?                         'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE ?                         'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   ?   ?   ?   A . n 
A 1 2   PRO 2   2   ?   ?   ?   A . n 
A 1 3   PRO 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   4   SER SER A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   TRP 6   6   6   TRP TRP A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   ARG 8   8   8   ARG ARG A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  VAL 10  10  10  VAL VAL A . n 
A 1 11  ASN 11  11  11  ASN ASN A . n 
A 1 12  PHE 12  12  12  PHE PHE A . n 
A 1 13  GLY 13  13  13  GLY GLY A . n 
A 1 14  SER 14  14  14  SER SER A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  TRP 16  16  16  TRP TRP A . n 
A 1 17  GLY 17  17  17  GLY GLY A . n 
A 1 18  PHE 18  18  18  PHE PHE A . n 
A 1 19  TRP 19  19  19  TRP TRP A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  PRO 22  22  22  PRO PRO A . n 
A 1 23  SER 23  23  23  SER SER A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  ILE 26  26  26  ILE ILE A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  SER 28  28  28  SER SER A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  HIS 30  30  30  HIS HIS A . n 
A 1 31  VAL 31  31  31  VAL VAL A . n 
A 1 32  ILE 32  32  32  ILE ILE A . n 
A 1 33  PRO 33  33  33  PRO PRO A . n 
A 1 34  GLN 34  34  34  GLN GLN A . n 
A 1 35  GLY 35  35  35  GLY GLY A . n 
A 1 36  THR 36  36  36  THR THR A . n 
A 1 37  GLN 37  37  37  GLN GLN A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  PHE 39  39  39  PHE PHE A . n 
A 1 40  PHE 40  40  40  PHE PHE A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  PRO 43  43  43  PRO PRO A . n 
A 1 44  THR 44  44  44  THR THR A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  ILE 47  47  47  ILE ILE A . n 
A 1 48  GLN 48  48  48  GLN GLN A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  HIS 50  50  50  HIS HIS A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  PHE 55  55  55  PHE PHE A . n 
A 1 56  CYS 56  56  56  CYS CYS A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  PHE 60  60  60  PHE PHE A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  ILE 64  64  64  ILE ILE A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  THR 69  69  69  THR THR A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  MET 71  71  71  MET MET A . n 
A 1 72  ILE 72  72  72  ILE ILE A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLU 74  74  74  GLU GLU A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  GLY 76  76  76  GLY GLY A . n 
A 1 77  ALA 77  77  77  ALA ALA A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  GLU 79  79  79  GLU GLU A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  THR 81  81  81  THR THR A . n 
A 1 82  VAL 82  82  82  VAL VAL A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  LEU 85  85  85  LEU LEU A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  ILE 87  87  87  ILE ILE A . n 
A 1 88  LYS 88  88  88  LYS LYS A . n 
A 1 89  ARG 89  89  89  ARG ARG A . n 
A 1 90  PRO 90  90  90  PRO PRO A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  GLU 93  93  93  GLU GLU A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  MET 95  95  95  MET MET A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 ARG 100 100 100 ARG ARG A . n 
A 1 101 MET 101 101 101 MET MET A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 HIS 104 104 104 HIS HIS A . n 
A 1 105 ALA 105 105 105 ALA ALA A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 MET 107 107 107 MET MET A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 ILE 109 109 109 ILE ILE A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 GLY 111 111 111 GLY GLY A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 GLN 117 117 117 GLN GLN A . n 
A 1 118 MET 118 118 118 MET MET A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 MET 120 120 120 MET MET A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 THR 123 123 123 THR THR A . n 
A 1 124 GLY 124 124 ?   ?   ?   A . n 
A 1 125 SER 125 125 ?   ?   ?   A . n 
A 1 126 ASN 126 126 ?   ?   ?   A . n 
A 1 127 ALA 127 127 ?   ?   ?   A . n 
A 1 128 LYS 128 128 ?   ?   ?   A . n 
A 1 129 SER 129 129 ?   ?   ?   A . n 
A 1 130 MET 130 130 ?   ?   ?   A . n 
A 1 131 ASP 131 131 ?   ?   ?   A . n 
A 1 132 LEU 132 132 132 LEU LEU A . n 
A 1 133 GLY 133 133 133 GLY GLY A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 PRO 136 136 136 PRO PRO A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 CYS 139 139 139 CYS CYS A . n 
A 1 140 GLY 140 140 140 GLY GLY A . n 
A 1 141 CYS 141 141 141 CYS CYS A . n 
A 1 142 PRO 142 142 142 PRO PRO A . n 
A 1 143 TYR 143 143 143 TYR TYR A . n 
A 1 144 ILE 144 144 144 ILE ILE A . n 
A 1 145 TYR 145 145 145 TYR TYR A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 ARG 147 147 147 ARG ARG A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 ASN 149 149 149 ASN ASN A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 TYR 151 151 151 TYR TYR A . n 
A 1 152 VAL 152 152 152 VAL VAL A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 ILE 154 154 154 ILE ILE A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 HIS 157 157 157 HIS HIS A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 ALA 159 159 159 ALA ALA A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 ARG 162 162 162 ARG ARG A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 ASN 165 165 165 ASN ASN A . n 
A 1 166 THR 166 166 166 THR THR A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 CYS 169 169 169 CYS CYS A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 THR 171 171 171 THR THR A . n 
A 1 172 GLN 172 172 172 GLN GLN A . n 
A 1 173 GLY 173 173 ?   ?   ?   A . n 
A 1 174 SER 174 174 ?   ?   ?   A . n 
A 1 175 GLU 175 175 ?   ?   ?   A . n 
A 1 176 GLY 176 176 ?   ?   ?   A . n 
A 1 177 GLU 177 177 ?   ?   ?   A . n 
A 1 178 ALA 178 178 ?   ?   ?   A . n 
A 1 179 MET 179 179 ?   ?   ?   A . n 
A 1 180 LEU 180 180 ?   ?   ?   A . n 
A 1 181 GLU 181 181 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        AG7 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   AG7 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          AG7 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     201 
_pdbx_nonpoly_scheme.auth_seq_num    201 
_pdbx_nonpoly_scheme.pdb_mon_id      AG7 
_pdbx_nonpoly_scheme.auth_mon_id     AG7 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? ? 1.21rc1_5156 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? iMOSFLM   ? ? ? .            2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? pointless ? ? ? .            3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP    ? ? ? .            4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DAP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     97.329 
_cell.length_a_esd                 ? 
_cell.length_b                     97.329 
_cell.length_b_esd                 ? 
_cell.length_c                     43.770 
_cell.length_c_esd                 ? 
_cell.volume                       359085.978 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DAP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DAP 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.09 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          60.24 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.3 M Sodium Formate, 0.1 M Sodium Citrate Tribasic:HCl, 22.5 % (v/v) PurePEGs Cocktail' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     298 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 S 2M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-03-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALS BEAMLINE 8.2.2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   8.2.2 
_diffrn_source.pdbx_synchrotron_site       ALS 
# 
_reflns.B_iso_Wilson_estimate                          50.06 
_reflns.entry_id                                       9DAP 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.71 
_reflns.d_resolution_low                               48.66 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     6699 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.78 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                1.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.86 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.06721 
_reflns.pdbx_Rpim_I_all                                0.04753 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.04753 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.71 
_reflns_shell.d_res_low                                     3.41 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           3.85 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             6292 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               1.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.963 
_reflns_shell.pdbx_CC_star                                  0.991 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.67 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               51.27 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9DAP 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.71 
_refine.ls_d_res_low                             48.66 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     6685 
_refine.ls_number_reflns_R_free                  318 
_refine.ls_number_reflns_R_work                  6367 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.79 
_refine.ls_percent_reflns_R_free                 4.76 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1889 
_refine.ls_R_factor_R_free                       0.2403 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1864 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 27.4137 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1818 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.71 
_refine_hist.d_res_low                        48.66 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               1260 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1217 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         43 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0064  ? 1290 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0065  ? 1748 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0531  ? 195  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0076  ? 221  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 15.5643 ? 458  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.71 3.41  . . 165 3117 99.67 . . . . 0.2594 . . . . . . . . . . . 0.2972 
'X-RAY DIFFRACTION' 3.41 48.66 . . 153 3250 99.91 . . . . 0.1579 . . . . . . . . . . . 0.2137 
# 
_struct.entry_id                     9DAP 
_struct.title                        'Human norovirus GII.3 protease in complex with rupintrivir' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DAP 
_struct_keywords.text            'Viral protease with inhibitor, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    B2DD26_9CALI 
_struct_ref.pdbx_db_accession          B2DD26 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQGTQEFFGVPTKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEAMLE
;
_struct_ref.pdbx_align_begin           1009 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9DAP 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 181 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             B2DD26 
_struct_ref_seq.db_align_beg                  1009 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1189 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       181 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ILE A 5   ? SER A 7   ? ILE A 5   SER A 7   5 ? 3 
HELX_P HELX_P2 AA2 HIS A 30  ? ILE A 32  ? HIS A 30  ILE A 32  5 ? 3 
HELX_P HELX_P3 AA3 LYS A 45  ? ILE A 47  ? LYS A 45  ILE A 47  5 ? 3 
HELX_P HELX_P4 AA4 THR A 135 ? CYS A 139 ? THR A 135 CYS A 139 5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        none 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            139 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           AG7 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C19 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             139 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            AG7 
_struct_conn.ptnr2_auth_seq_id             201 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.765 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      AG7 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      139 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       AG7 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        201 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       139 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               C19 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        AG7 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 9   ? PHE A 12  ? ILE A 9   PHE A 12  
AA1 2 GLY A 15  ? TRP A 19  ? GLY A 15  TRP A 19  
AA1 3 LEU A 24  ? SER A 28  ? LEU A 24  SER A 28  
AA1 4 PHE A 55  ? ARG A 59  ? PHE A 55  ARG A 59  
AA1 5 GLN A 48  ? SER A 52  ? GLN A 48  SER A 52  
AA2 1 GLU A 38  ? PHE A 39  ? GLU A 38  PHE A 39  
AA2 2 VAL A 42  ? PRO A 43  ? VAL A 42  PRO A 43  
AA3 1 ILE A 72  ? LEU A 73  ? ILE A 72  LEU A 73  
AA3 2 ASP A 150 ? ALA A 160 ? ASP A 150 ALA A 160 
AA3 3 THR A 166 ? ALA A 170 ? THR A 166 ALA A 170 
AA3 4 ARG A 112 ? LEU A 121 ? ARG A 112 LEU A 121 
AA3 5 LEU A 94  ? ILE A 109 ? LEU A 94  ILE A 109 
AA3 6 VAL A 82  ? LYS A 88  ? VAL A 82  LYS A 88  
AA3 7 PRO A 142 ? ARG A 147 ? PRO A 142 ARG A 147 
AA3 8 ASP A 150 ? ALA A 160 ? ASP A 150 ALA A 160 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 10  ? N VAL A 10  O GLY A 17  ? O GLY A 17  
AA1 2 3 N PHE A 18  ? N PHE A 18  O ILE A 26  ? O ILE A 26  
AA1 3 4 N PHE A 25  ? N PHE A 25  O LEU A 58  ? O LEU A 58  
AA1 4 5 O PHE A 55  ? O PHE A 55  N SER A 52  ? N SER A 52  
AA2 1 2 N PHE A 39  ? N PHE A 39  O VAL A 42  ? O VAL A 42  
AA3 1 2 N ILE A 72  ? N ILE A 72  O VAL A 153 ? O VAL A 153 
AA3 2 3 N ALA A 159 ? N ALA A 159 O ILE A 168 ? O ILE A 168 
AA3 3 4 O VAL A 167 ? O VAL A 167 N GLY A 119 ? N GLY A 119 
AA3 4 5 O VAL A 114 ? O VAL A 114 N MET A 107 ? N MET A 107 
AA3 5 6 O MET A 95  ? O MET A 95  N ILE A 87  ? N ILE A 87  
AA3 6 7 N THR A 84  ? N THR A 84  O ILE A 144 ? O ILE A 144 
AA3 7 8 N ARG A 147 ? N ARG A 147 O ASP A 150 ? O ASP A 150 
# 
_pdbx_entry_details.entry_id                   9DAP 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
_pdbx_refine_tls.id               1 
_pdbx_refine_tls.pdbx_refine_id   'X-RAY DIFFRACTION' 
_pdbx_refine_tls.details          ? 
_pdbx_refine_tls.method           refined 
_pdbx_refine_tls.origin_x         -31.8519824581 
_pdbx_refine_tls.origin_y         -25.4506536934 
_pdbx_refine_tls.origin_z         1.5030171816 
_pdbx_refine_tls.T[1][1]          0.319308307315 
_pdbx_refine_tls.T[1][1]_esd      ? 
_pdbx_refine_tls.T[1][2]          -0.018015792616 
_pdbx_refine_tls.T[1][2]_esd      ? 
_pdbx_refine_tls.T[1][3]          -0.0136716697205 
_pdbx_refine_tls.T[1][3]_esd      ? 
_pdbx_refine_tls.T[2][2]          0.316881438624 
_pdbx_refine_tls.T[2][2]_esd      ? 
_pdbx_refine_tls.T[2][3]          -0.0375812930653 
_pdbx_refine_tls.T[2][3]_esd      ? 
_pdbx_refine_tls.T[3][3]          0.282268825999 
_pdbx_refine_tls.T[3][3]_esd      ? 
_pdbx_refine_tls.L[1][1]          2.83513076851 
_pdbx_refine_tls.L[1][1]_esd      ? 
_pdbx_refine_tls.L[1][2]          -0.739197987823 
_pdbx_refine_tls.L[1][2]_esd      ? 
_pdbx_refine_tls.L[1][3]          -0.00827904385745 
_pdbx_refine_tls.L[1][3]_esd      ? 
_pdbx_refine_tls.L[2][2]          1.96505488844 
_pdbx_refine_tls.L[2][2]_esd      ? 
_pdbx_refine_tls.L[2][3]          -0.444455580858 
_pdbx_refine_tls.L[2][3]_esd      ? 
_pdbx_refine_tls.L[3][3]          0.769385240569 
_pdbx_refine_tls.L[3][3]_esd      ? 
_pdbx_refine_tls.S[1][1]          0.00787835686272 
_pdbx_refine_tls.S[1][1]_esd      ? 
_pdbx_refine_tls.S[1][2]          0.00730320194171 
_pdbx_refine_tls.S[1][2]_esd      ? 
_pdbx_refine_tls.S[1][3]          0.162288522254 
_pdbx_refine_tls.S[1][3]_esd      ? 
_pdbx_refine_tls.S[2][1]          -0.151598019665 
_pdbx_refine_tls.S[2][1]_esd      ? 
_pdbx_refine_tls.S[2][2]          -0.00068094084821 
_pdbx_refine_tls.S[2][2]_esd      ? 
_pdbx_refine_tls.S[2][3]          0.00680907334689 
_pdbx_refine_tls.S[2][3]_esd      ? 
_pdbx_refine_tls.S[3][1]          -0.00834335599332 
_pdbx_refine_tls.S[3][1]_esd      ? 
_pdbx_refine_tls.S[3][2]          0.0474232092636 
_pdbx_refine_tls.S[3][2]_esd      ? 
_pdbx_refine_tls.S[3][3]          -7.93063772178e-09 
_pdbx_refine_tls.S[3][3]_esd      ? 
# 
_pdbx_refine_tls_group.id                  1 
_pdbx_refine_tls_group.pdbx_refine_id      'X-RAY DIFFRACTION' 
_pdbx_refine_tls_group.refine_tls_id       1 
_pdbx_refine_tls_group.beg_label_asym_id   A 
_pdbx_refine_tls_group.beg_label_seq_id    1 
_pdbx_refine_tls_group.beg_auth_asym_id    A 
_pdbx_refine_tls_group.beg_auth_seq_id     4 
_pdbx_refine_tls_group.beg_PDB_ins_code    ? 
_pdbx_refine_tls_group.end_label_asym_id   B 
_pdbx_refine_tls_group.end_label_seq_id    ? 
_pdbx_refine_tls_group.end_auth_asym_id    A 
_pdbx_refine_tls_group.end_auth_seq_id     201 
_pdbx_refine_tls_group.end_PDB_ins_code    ? 
_pdbx_refine_tls_group.selection           ? 
_pdbx_refine_tls_group.selection_details   all 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ALA 1   ? A ALA 1   
2  1 Y 1 A PRO 2   ? A PRO 2   
3  1 Y 1 A PRO 3   ? A PRO 3   
4  1 Y 1 A GLY 124 ? A GLY 124 
5  1 Y 1 A SER 125 ? A SER 125 
6  1 Y 1 A ASN 126 ? A ASN 126 
7  1 Y 1 A ALA 127 ? A ALA 127 
8  1 Y 1 A LYS 128 ? A LYS 128 
9  1 Y 1 A SER 129 ? A SER 129 
10 1 Y 1 A MET 130 ? A MET 130 
11 1 Y 1 A ASP 131 ? A ASP 131 
12 1 Y 1 A GLY 173 ? A GLY 173 
13 1 Y 1 A SER 174 ? A SER 174 
14 1 Y 1 A GLU 175 ? A GLU 175 
15 1 Y 1 A GLY 176 ? A GLY 176 
16 1 Y 1 A GLU 177 ? A GLU 177 
17 1 Y 1 A ALA 178 ? A ALA 178 
18 1 Y 1 A MET 179 ? A MET 179 
19 1 Y 1 A LEU 180 ? A LEU 180 
20 1 Y 1 A GLU 181 ? A GLU 181 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
AG7 C01  C N N 1   
AG7 C02  C N N 2   
AG7 O03  O N N 3   
AG7 C04  C N R 4   
AG7 C05  C N N 5   
AG7 C06  C Y N 6   
AG7 C07  C Y N 7   
AG7 C08  C Y N 8   
AG7 C09  C Y N 9   
AG7 C10  C Y N 10  
AG7 C11  C Y N 11  
AG7 N12  N N N 12  
AG7 C13  C N R 13  
AG7 C14  C N N 14  
AG7 C15  C N S 15  
AG7 C16  C N N 16  
AG7 N17  N N N 17  
AG7 O18  O N N 18  
AG7 C19  C N N 19  
AG7 C20  C N N 20  
AG7 C21  C N N 21  
AG7 O22  O N N 22  
AG7 O23  O N N 23  
AG7 C47  C N N 24  
AG7 O48  O N N 25  
AG7 C50  C N N 26  
AG7 C53  C N N 27  
AG7 C57  C N S 28  
AG7 N58  N N N 29  
AG7 C59  C N N 30  
AG7 O60  O N N 31  
AG7 C78  C N N 32  
AG7 C81  C N N 33  
AG7 F1   F N N 34  
AG7 C82  C N N 35  
AG7 C83  C N N 36  
AG7 C84  C N N 37  
AG7 C1   C Y N 38  
AG7 C2   C Y N 39  
AG7 C3   C Y N 40  
AG7 O4   O Y N 41  
AG7 N5   N Y N 42  
AG7 C4   C N N 43  
AG7 H2   H N N 44  
AG7 H3   H N N 45  
AG7 H27  H N N 46  
AG7 H28  H N N 47  
AG7 H29  H N N 48  
AG7 H30  H N N 49  
AG7 H31  H N N 50  
AG7 H33  H N N 51  
AG7 H34  H N N 52  
AG7 H49  H N N 53  
AG7 H91  H N N 54  
AG7 H35  H N N 55  
AG7 H36  H N N 56  
AG7 H94  H N N 57  
AG7 H39  H N N 58  
AG7 H191 H N N 59  
AG7 H192 H N N 60  
AG7 H41  H N N 61  
AG7 H42  H N N 62  
AG7 H51  H N N 63  
AG7 H52  H N N 64  
AG7 H53  H N N 65  
AG7 H54  H N N 66  
AG7 H56  H N N 67  
AG7 H77  H N N 68  
AG7 H61  H N N 69  
AG7 H79  H N N 70  
AG7 H82  H N N 71  
AG7 H84  H N N 72  
AG7 H85  H N N 73  
AG7 H86  H N N 74  
AG7 H87  H N N 75  
AG7 H88  H N N 76  
AG7 H89  H N N 77  
AG7 H90  H N N 78  
AG7 H92  H N N 79  
AG7 H93  H N N 80  
AG7 H8   H N N 81  
AG7 H5   H N N 82  
AG7 H6   H N N 83  
AG7 H7   H N N 84  
ALA N    N N N 85  
ALA CA   C N S 86  
ALA C    C N N 87  
ALA O    O N N 88  
ALA CB   C N N 89  
ALA OXT  O N N 90  
ALA H    H N N 91  
ALA H2   H N N 92  
ALA HA   H N N 93  
ALA HB1  H N N 94  
ALA HB2  H N N 95  
ALA HB3  H N N 96  
ALA HXT  H N N 97  
ARG N    N N N 98  
ARG CA   C N S 99  
ARG C    C N N 100 
ARG O    O N N 101 
ARG CB   C N N 102 
ARG CG   C N N 103 
ARG CD   C N N 104 
ARG NE   N N N 105 
ARG CZ   C N N 106 
ARG NH1  N N N 107 
ARG NH2  N N N 108 
ARG OXT  O N N 109 
ARG H    H N N 110 
ARG H2   H N N 111 
ARG HA   H N N 112 
ARG HB2  H N N 113 
ARG HB3  H N N 114 
ARG HG2  H N N 115 
ARG HG3  H N N 116 
ARG HD2  H N N 117 
ARG HD3  H N N 118 
ARG HE   H N N 119 
ARG HH11 H N N 120 
ARG HH12 H N N 121 
ARG HH21 H N N 122 
ARG HH22 H N N 123 
ARG HXT  H N N 124 
ASN N    N N N 125 
ASN CA   C N S 126 
ASN C    C N N 127 
ASN O    O N N 128 
ASN CB   C N N 129 
ASN CG   C N N 130 
ASN OD1  O N N 131 
ASN ND2  N N N 132 
ASN OXT  O N N 133 
ASN H    H N N 134 
ASN H2   H N N 135 
ASN HA   H N N 136 
ASN HB2  H N N 137 
ASN HB3  H N N 138 
ASN HD21 H N N 139 
ASN HD22 H N N 140 
ASN HXT  H N N 141 
ASP N    N N N 142 
ASP CA   C N S 143 
ASP C    C N N 144 
ASP O    O N N 145 
ASP CB   C N N 146 
ASP CG   C N N 147 
ASP OD1  O N N 148 
ASP OD2  O N N 149 
ASP OXT  O N N 150 
ASP H    H N N 151 
ASP H2   H N N 152 
ASP HA   H N N 153 
ASP HB2  H N N 154 
ASP HB3  H N N 155 
ASP HD2  H N N 156 
ASP HXT  H N N 157 
CYS N    N N N 158 
CYS CA   C N R 159 
CYS C    C N N 160 
CYS O    O N N 161 
CYS CB   C N N 162 
CYS SG   S N N 163 
CYS OXT  O N N 164 
CYS H    H N N 165 
CYS H2   H N N 166 
CYS HA   H N N 167 
CYS HB2  H N N 168 
CYS HB3  H N N 169 
CYS HG   H N N 170 
CYS HXT  H N N 171 
GLN N    N N N 172 
GLN CA   C N S 173 
GLN C    C N N 174 
GLN O    O N N 175 
GLN CB   C N N 176 
GLN CG   C N N 177 
GLN CD   C N N 178 
GLN OE1  O N N 179 
GLN NE2  N N N 180 
GLN OXT  O N N 181 
GLN H    H N N 182 
GLN H2   H N N 183 
GLN HA   H N N 184 
GLN HB2  H N N 185 
GLN HB3  H N N 186 
GLN HG2  H N N 187 
GLN HG3  H N N 188 
GLN HE21 H N N 189 
GLN HE22 H N N 190 
GLN HXT  H N N 191 
GLU N    N N N 192 
GLU CA   C N S 193 
GLU C    C N N 194 
GLU O    O N N 195 
GLU CB   C N N 196 
GLU CG   C N N 197 
GLU CD   C N N 198 
GLU OE1  O N N 199 
GLU OE2  O N N 200 
GLU OXT  O N N 201 
GLU H    H N N 202 
GLU H2   H N N 203 
GLU HA   H N N 204 
GLU HB2  H N N 205 
GLU HB3  H N N 206 
GLU HG2  H N N 207 
GLU HG3  H N N 208 
GLU HE2  H N N 209 
GLU HXT  H N N 210 
GLY N    N N N 211 
GLY CA   C N N 212 
GLY C    C N N 213 
GLY O    O N N 214 
GLY OXT  O N N 215 
GLY H    H N N 216 
GLY H2   H N N 217 
GLY HA2  H N N 218 
GLY HA3  H N N 219 
GLY HXT  H N N 220 
HIS N    N N N 221 
HIS CA   C N S 222 
HIS C    C N N 223 
HIS O    O N N 224 
HIS CB   C N N 225 
HIS CG   C Y N 226 
HIS ND1  N Y N 227 
HIS CD2  C Y N 228 
HIS CE1  C Y N 229 
HIS NE2  N Y N 230 
HIS OXT  O N N 231 
HIS H    H N N 232 
HIS H2   H N N 233 
HIS HA   H N N 234 
HIS HB2  H N N 235 
HIS HB3  H N N 236 
HIS HD1  H N N 237 
HIS HD2  H N N 238 
HIS HE1  H N N 239 
HIS HE2  H N N 240 
HIS HXT  H N N 241 
ILE N    N N N 242 
ILE CA   C N S 243 
ILE C    C N N 244 
ILE O    O N N 245 
ILE CB   C N S 246 
ILE CG1  C N N 247 
ILE CG2  C N N 248 
ILE CD1  C N N 249 
ILE OXT  O N N 250 
ILE H    H N N 251 
ILE H2   H N N 252 
ILE HA   H N N 253 
ILE HB   H N N 254 
ILE HG12 H N N 255 
ILE HG13 H N N 256 
ILE HG21 H N N 257 
ILE HG22 H N N 258 
ILE HG23 H N N 259 
ILE HD11 H N N 260 
ILE HD12 H N N 261 
ILE HD13 H N N 262 
ILE HXT  H N N 263 
LEU N    N N N 264 
LEU CA   C N S 265 
LEU C    C N N 266 
LEU O    O N N 267 
LEU CB   C N N 268 
LEU CG   C N N 269 
LEU CD1  C N N 270 
LEU CD2  C N N 271 
LEU OXT  O N N 272 
LEU H    H N N 273 
LEU H2   H N N 274 
LEU HA   H N N 275 
LEU HB2  H N N 276 
LEU HB3  H N N 277 
LEU HG   H N N 278 
LEU HD11 H N N 279 
LEU HD12 H N N 280 
LEU HD13 H N N 281 
LEU HD21 H N N 282 
LEU HD22 H N N 283 
LEU HD23 H N N 284 
LEU HXT  H N N 285 
LYS N    N N N 286 
LYS CA   C N S 287 
LYS C    C N N 288 
LYS O    O N N 289 
LYS CB   C N N 290 
LYS CG   C N N 291 
LYS CD   C N N 292 
LYS CE   C N N 293 
LYS NZ   N N N 294 
LYS OXT  O N N 295 
LYS H    H N N 296 
LYS H2   H N N 297 
LYS HA   H N N 298 
LYS HB2  H N N 299 
LYS HB3  H N N 300 
LYS HG2  H N N 301 
LYS HG3  H N N 302 
LYS HD2  H N N 303 
LYS HD3  H N N 304 
LYS HE2  H N N 305 
LYS HE3  H N N 306 
LYS HZ1  H N N 307 
LYS HZ2  H N N 308 
LYS HZ3  H N N 309 
LYS HXT  H N N 310 
MET N    N N N 311 
MET CA   C N S 312 
MET C    C N N 313 
MET O    O N N 314 
MET CB   C N N 315 
MET CG   C N N 316 
MET SD   S N N 317 
MET CE   C N N 318 
MET OXT  O N N 319 
MET H    H N N 320 
MET H2   H N N 321 
MET HA   H N N 322 
MET HB2  H N N 323 
MET HB3  H N N 324 
MET HG2  H N N 325 
MET HG3  H N N 326 
MET HE1  H N N 327 
MET HE2  H N N 328 
MET HE3  H N N 329 
MET HXT  H N N 330 
PHE N    N N N 331 
PHE CA   C N S 332 
PHE C    C N N 333 
PHE O    O N N 334 
PHE CB   C N N 335 
PHE CG   C Y N 336 
PHE CD1  C Y N 337 
PHE CD2  C Y N 338 
PHE CE1  C Y N 339 
PHE CE2  C Y N 340 
PHE CZ   C Y N 341 
PHE OXT  O N N 342 
PHE H    H N N 343 
PHE H2   H N N 344 
PHE HA   H N N 345 
PHE HB2  H N N 346 
PHE HB3  H N N 347 
PHE HD1  H N N 348 
PHE HD2  H N N 349 
PHE HE1  H N N 350 
PHE HE2  H N N 351 
PHE HZ   H N N 352 
PHE HXT  H N N 353 
PRO N    N N N 354 
PRO CA   C N S 355 
PRO C    C N N 356 
PRO O    O N N 357 
PRO CB   C N N 358 
PRO CG   C N N 359 
PRO CD   C N N 360 
PRO OXT  O N N 361 
PRO H    H N N 362 
PRO HA   H N N 363 
PRO HB2  H N N 364 
PRO HB3  H N N 365 
PRO HG2  H N N 366 
PRO HG3  H N N 367 
PRO HD2  H N N 368 
PRO HD3  H N N 369 
PRO HXT  H N N 370 
SER N    N N N 371 
SER CA   C N S 372 
SER C    C N N 373 
SER O    O N N 374 
SER CB   C N N 375 
SER OG   O N N 376 
SER OXT  O N N 377 
SER H    H N N 378 
SER H2   H N N 379 
SER HA   H N N 380 
SER HB2  H N N 381 
SER HB3  H N N 382 
SER HG   H N N 383 
SER HXT  H N N 384 
THR N    N N N 385 
THR CA   C N S 386 
THR C    C N N 387 
THR O    O N N 388 
THR CB   C N R 389 
THR OG1  O N N 390 
THR CG2  C N N 391 
THR OXT  O N N 392 
THR H    H N N 393 
THR H2   H N N 394 
THR HA   H N N 395 
THR HB   H N N 396 
THR HG1  H N N 397 
THR HG21 H N N 398 
THR HG22 H N N 399 
THR HG23 H N N 400 
THR HXT  H N N 401 
TRP N    N N N 402 
TRP CA   C N S 403 
TRP C    C N N 404 
TRP O    O N N 405 
TRP CB   C N N 406 
TRP CG   C Y N 407 
TRP CD1  C Y N 408 
TRP CD2  C Y N 409 
TRP NE1  N Y N 410 
TRP CE2  C Y N 411 
TRP CE3  C Y N 412 
TRP CZ2  C Y N 413 
TRP CZ3  C Y N 414 
TRP CH2  C Y N 415 
TRP OXT  O N N 416 
TRP H    H N N 417 
TRP H2   H N N 418 
TRP HA   H N N 419 
TRP HB2  H N N 420 
TRP HB3  H N N 421 
TRP HD1  H N N 422 
TRP HE1  H N N 423 
TRP HE3  H N N 424 
TRP HZ2  H N N 425 
TRP HZ3  H N N 426 
TRP HH2  H N N 427 
TRP HXT  H N N 428 
TYR N    N N N 429 
TYR CA   C N S 430 
TYR C    C N N 431 
TYR O    O N N 432 
TYR CB   C N N 433 
TYR CG   C Y N 434 
TYR CD1  C Y N 435 
TYR CD2  C Y N 436 
TYR CE1  C Y N 437 
TYR CE2  C Y N 438 
TYR CZ   C Y N 439 
TYR OH   O N N 440 
TYR OXT  O N N 441 
TYR H    H N N 442 
TYR H2   H N N 443 
TYR HA   H N N 444 
TYR HB2  H N N 445 
TYR HB3  H N N 446 
TYR HD1  H N N 447 
TYR HD2  H N N 448 
TYR HE1  H N N 449 
TYR HE2  H N N 450 
TYR HH   H N N 451 
TYR HXT  H N N 452 
VAL N    N N N 453 
VAL CA   C N S 454 
VAL C    C N N 455 
VAL O    O N N 456 
VAL CB   C N N 457 
VAL CG1  C N N 458 
VAL CG2  C N N 459 
VAL OXT  O N N 460 
VAL H    H N N 461 
VAL H2   H N N 462 
VAL HA   H N N 463 
VAL HB   H N N 464 
VAL HG11 H N N 465 
VAL HG12 H N N 466 
VAL HG13 H N N 467 
VAL HG21 H N N 468 
VAL HG22 H N N 469 
VAL HG23 H N N 470 
VAL HXT  H N N 471 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
AG7 C01 C02  sing N N 1   
AG7 C01 O03  doub N N 2   
AG7 C01 C57  sing N N 3   
AG7 C02 C04  sing N N 4   
AG7 C02 H2   sing N N 5   
AG7 C02 H3   sing N N 6   
AG7 C04 C05  sing N N 7   
AG7 C04 C47  sing N N 8   
AG7 C04 H27  sing N N 9   
AG7 C05 C06  sing N N 10  
AG7 C05 H28  sing N N 11  
AG7 C05 H29  sing N N 12  
AG7 C06 C07  doub Y N 13  
AG7 C06 C11  sing Y N 14  
AG7 C07 C08  sing Y N 15  
AG7 C07 H30  sing N N 16  
AG7 C08 C09  doub Y N 17  
AG7 C08 H31  sing N N 18  
AG7 C09 C10  sing Y N 19  
AG7 C09 F1   sing N N 20  
AG7 C10 C11  doub Y N 21  
AG7 C10 H33  sing N N 22  
AG7 C11 H34  sing N N 23  
AG7 N12 C13  sing N N 24  
AG7 N12 C47  sing N N 25  
AG7 N12 H49  sing N N 26  
AG7 C13 C14  sing N N 27  
AG7 C13 C19  sing N N 28  
AG7 C13 H91  sing N N 29  
AG7 C14 C15  sing N N 30  
AG7 C14 H35  sing N N 31  
AG7 C14 H36  sing N N 32  
AG7 C15 C16  sing N N 33  
AG7 C15 C84  sing N N 34  
AG7 C15 H94  sing N N 35  
AG7 C16 N17  sing N N 36  
AG7 C16 O18  doub N N 37  
AG7 N17 C83  sing N N 38  
AG7 N17 H39  sing N N 39  
AG7 C19 C20  sing N N 40  
AG7 C19 H191 sing N N 41  
AG7 C19 H192 sing N N 42  
AG7 C20 C21  sing N N 43  
AG7 C20 H41  sing N N 44  
AG7 C20 H42  sing N N 45  
AG7 C21 O22  sing N N 46  
AG7 C21 O23  doub N N 47  
AG7 O22 C50  sing N N 48  
AG7 C47 O48  doub N N 49  
AG7 C50 C53  sing N N 50  
AG7 C50 H51  sing N N 51  
AG7 C50 H52  sing N N 52  
AG7 C53 H53  sing N N 53  
AG7 C53 H54  sing N N 54  
AG7 C53 H56  sing N N 55  
AG7 C57 N58  sing N N 56  
AG7 C57 C78  sing N N 57  
AG7 C57 H77  sing N N 58  
AG7 N58 C59  sing N N 59  
AG7 N58 H61  sing N N 60  
AG7 C59 O60  doub N N 61  
AG7 C59 C1   sing N N 62  
AG7 C78 C81  sing N N 63  
AG7 C78 C82  sing N N 64  
AG7 C78 H79  sing N N 65  
AG7 C81 H82  sing N N 66  
AG7 C81 H84  sing N N 67  
AG7 C81 H85  sing N N 68  
AG7 C82 H86  sing N N 69  
AG7 C82 H87  sing N N 70  
AG7 C82 H88  sing N N 71  
AG7 C83 C84  sing N N 72  
AG7 C83 H89  sing N N 73  
AG7 C83 H90  sing N N 74  
AG7 C84 H92  sing N N 75  
AG7 C84 H93  sing N N 76  
AG7 C1  C2   sing Y N 77  
AG7 C1  N5   doub Y N 78  
AG7 C2  C3   doub Y N 79  
AG7 C2  H8   sing N N 80  
AG7 C3  O4   sing Y N 81  
AG7 C3  C4   sing N N 82  
AG7 O4  N5   sing Y N 83  
AG7 C4  H5   sing N N 84  
AG7 C4  H6   sing N N 85  
AG7 C4  H7   sing N N 86  
ALA N   CA   sing N N 87  
ALA N   H    sing N N 88  
ALA N   H2   sing N N 89  
ALA CA  C    sing N N 90  
ALA CA  CB   sing N N 91  
ALA CA  HA   sing N N 92  
ALA C   O    doub N N 93  
ALA C   OXT  sing N N 94  
ALA CB  HB1  sing N N 95  
ALA CB  HB2  sing N N 96  
ALA CB  HB3  sing N N 97  
ALA OXT HXT  sing N N 98  
ARG N   CA   sing N N 99  
ARG N   H    sing N N 100 
ARG N   H2   sing N N 101 
ARG CA  C    sing N N 102 
ARG CA  CB   sing N N 103 
ARG CA  HA   sing N N 104 
ARG C   O    doub N N 105 
ARG C   OXT  sing N N 106 
ARG CB  CG   sing N N 107 
ARG CB  HB2  sing N N 108 
ARG CB  HB3  sing N N 109 
ARG CG  CD   sing N N 110 
ARG CG  HG2  sing N N 111 
ARG CG  HG3  sing N N 112 
ARG CD  NE   sing N N 113 
ARG CD  HD2  sing N N 114 
ARG CD  HD3  sing N N 115 
ARG NE  CZ   sing N N 116 
ARG NE  HE   sing N N 117 
ARG CZ  NH1  sing N N 118 
ARG CZ  NH2  doub N N 119 
ARG NH1 HH11 sing N N 120 
ARG NH1 HH12 sing N N 121 
ARG NH2 HH21 sing N N 122 
ARG NH2 HH22 sing N N 123 
ARG OXT HXT  sing N N 124 
ASN N   CA   sing N N 125 
ASN N   H    sing N N 126 
ASN N   H2   sing N N 127 
ASN CA  C    sing N N 128 
ASN CA  CB   sing N N 129 
ASN CA  HA   sing N N 130 
ASN C   O    doub N N 131 
ASN C   OXT  sing N N 132 
ASN CB  CG   sing N N 133 
ASN CB  HB2  sing N N 134 
ASN CB  HB3  sing N N 135 
ASN CG  OD1  doub N N 136 
ASN CG  ND2  sing N N 137 
ASN ND2 HD21 sing N N 138 
ASN ND2 HD22 sing N N 139 
ASN OXT HXT  sing N N 140 
ASP N   CA   sing N N 141 
ASP N   H    sing N N 142 
ASP N   H2   sing N N 143 
ASP CA  C    sing N N 144 
ASP CA  CB   sing N N 145 
ASP CA  HA   sing N N 146 
ASP C   O    doub N N 147 
ASP C   OXT  sing N N 148 
ASP CB  CG   sing N N 149 
ASP CB  HB2  sing N N 150 
ASP CB  HB3  sing N N 151 
ASP CG  OD1  doub N N 152 
ASP CG  OD2  sing N N 153 
ASP OD2 HD2  sing N N 154 
ASP OXT HXT  sing N N 155 
CYS N   CA   sing N N 156 
CYS N   H    sing N N 157 
CYS N   H2   sing N N 158 
CYS CA  C    sing N N 159 
CYS CA  CB   sing N N 160 
CYS CA  HA   sing N N 161 
CYS C   O    doub N N 162 
CYS C   OXT  sing N N 163 
CYS CB  SG   sing N N 164 
CYS CB  HB2  sing N N 165 
CYS CB  HB3  sing N N 166 
CYS SG  HG   sing N N 167 
CYS OXT HXT  sing N N 168 
GLN N   CA   sing N N 169 
GLN N   H    sing N N 170 
GLN N   H2   sing N N 171 
GLN CA  C    sing N N 172 
GLN CA  CB   sing N N 173 
GLN CA  HA   sing N N 174 
GLN C   O    doub N N 175 
GLN C   OXT  sing N N 176 
GLN CB  CG   sing N N 177 
GLN CB  HB2  sing N N 178 
GLN CB  HB3  sing N N 179 
GLN CG  CD   sing N N 180 
GLN CG  HG2  sing N N 181 
GLN CG  HG3  sing N N 182 
GLN CD  OE1  doub N N 183 
GLN CD  NE2  sing N N 184 
GLN NE2 HE21 sing N N 185 
GLN NE2 HE22 sing N N 186 
GLN OXT HXT  sing N N 187 
GLU N   CA   sing N N 188 
GLU N   H    sing N N 189 
GLU N   H2   sing N N 190 
GLU CA  C    sing N N 191 
GLU CA  CB   sing N N 192 
GLU CA  HA   sing N N 193 
GLU C   O    doub N N 194 
GLU C   OXT  sing N N 195 
GLU CB  CG   sing N N 196 
GLU CB  HB2  sing N N 197 
GLU CB  HB3  sing N N 198 
GLU CG  CD   sing N N 199 
GLU CG  HG2  sing N N 200 
GLU CG  HG3  sing N N 201 
GLU CD  OE1  doub N N 202 
GLU CD  OE2  sing N N 203 
GLU OE2 HE2  sing N N 204 
GLU OXT HXT  sing N N 205 
GLY N   CA   sing N N 206 
GLY N   H    sing N N 207 
GLY N   H2   sing N N 208 
GLY CA  C    sing N N 209 
GLY CA  HA2  sing N N 210 
GLY CA  HA3  sing N N 211 
GLY C   O    doub N N 212 
GLY C   OXT  sing N N 213 
GLY OXT HXT  sing N N 214 
HIS N   CA   sing N N 215 
HIS N   H    sing N N 216 
HIS N   H2   sing N N 217 
HIS CA  C    sing N N 218 
HIS CA  CB   sing N N 219 
HIS CA  HA   sing N N 220 
HIS C   O    doub N N 221 
HIS C   OXT  sing N N 222 
HIS CB  CG   sing N N 223 
HIS CB  HB2  sing N N 224 
HIS CB  HB3  sing N N 225 
HIS CG  ND1  sing Y N 226 
HIS CG  CD2  doub Y N 227 
HIS ND1 CE1  doub Y N 228 
HIS ND1 HD1  sing N N 229 
HIS CD2 NE2  sing Y N 230 
HIS CD2 HD2  sing N N 231 
HIS CE1 NE2  sing Y N 232 
HIS CE1 HE1  sing N N 233 
HIS NE2 HE2  sing N N 234 
HIS OXT HXT  sing N N 235 
ILE N   CA   sing N N 236 
ILE N   H    sing N N 237 
ILE N   H2   sing N N 238 
ILE CA  C    sing N N 239 
ILE CA  CB   sing N N 240 
ILE CA  HA   sing N N 241 
ILE C   O    doub N N 242 
ILE C   OXT  sing N N 243 
ILE CB  CG1  sing N N 244 
ILE CB  CG2  sing N N 245 
ILE CB  HB   sing N N 246 
ILE CG1 CD1  sing N N 247 
ILE CG1 HG12 sing N N 248 
ILE CG1 HG13 sing N N 249 
ILE CG2 HG21 sing N N 250 
ILE CG2 HG22 sing N N 251 
ILE CG2 HG23 sing N N 252 
ILE CD1 HD11 sing N N 253 
ILE CD1 HD12 sing N N 254 
ILE CD1 HD13 sing N N 255 
ILE OXT HXT  sing N N 256 
LEU N   CA   sing N N 257 
LEU N   H    sing N N 258 
LEU N   H2   sing N N 259 
LEU CA  C    sing N N 260 
LEU CA  CB   sing N N 261 
LEU CA  HA   sing N N 262 
LEU C   O    doub N N 263 
LEU C   OXT  sing N N 264 
LEU CB  CG   sing N N 265 
LEU CB  HB2  sing N N 266 
LEU CB  HB3  sing N N 267 
LEU CG  CD1  sing N N 268 
LEU CG  CD2  sing N N 269 
LEU CG  HG   sing N N 270 
LEU CD1 HD11 sing N N 271 
LEU CD1 HD12 sing N N 272 
LEU CD1 HD13 sing N N 273 
LEU CD2 HD21 sing N N 274 
LEU CD2 HD22 sing N N 275 
LEU CD2 HD23 sing N N 276 
LEU OXT HXT  sing N N 277 
LYS N   CA   sing N N 278 
LYS N   H    sing N N 279 
LYS N   H2   sing N N 280 
LYS CA  C    sing N N 281 
LYS CA  CB   sing N N 282 
LYS CA  HA   sing N N 283 
LYS C   O    doub N N 284 
LYS C   OXT  sing N N 285 
LYS CB  CG   sing N N 286 
LYS CB  HB2  sing N N 287 
LYS CB  HB3  sing N N 288 
LYS CG  CD   sing N N 289 
LYS CG  HG2  sing N N 290 
LYS CG  HG3  sing N N 291 
LYS CD  CE   sing N N 292 
LYS CD  HD2  sing N N 293 
LYS CD  HD3  sing N N 294 
LYS CE  NZ   sing N N 295 
LYS CE  HE2  sing N N 296 
LYS CE  HE3  sing N N 297 
LYS NZ  HZ1  sing N N 298 
LYS NZ  HZ2  sing N N 299 
LYS NZ  HZ3  sing N N 300 
LYS OXT HXT  sing N N 301 
MET N   CA   sing N N 302 
MET N   H    sing N N 303 
MET N   H2   sing N N 304 
MET CA  C    sing N N 305 
MET CA  CB   sing N N 306 
MET CA  HA   sing N N 307 
MET C   O    doub N N 308 
MET C   OXT  sing N N 309 
MET CB  CG   sing N N 310 
MET CB  HB2  sing N N 311 
MET CB  HB3  sing N N 312 
MET CG  SD   sing N N 313 
MET CG  HG2  sing N N 314 
MET CG  HG3  sing N N 315 
MET SD  CE   sing N N 316 
MET CE  HE1  sing N N 317 
MET CE  HE2  sing N N 318 
MET CE  HE3  sing N N 319 
MET OXT HXT  sing N N 320 
PHE N   CA   sing N N 321 
PHE N   H    sing N N 322 
PHE N   H2   sing N N 323 
PHE CA  C    sing N N 324 
PHE CA  CB   sing N N 325 
PHE CA  HA   sing N N 326 
PHE C   O    doub N N 327 
PHE C   OXT  sing N N 328 
PHE CB  CG   sing N N 329 
PHE CB  HB2  sing N N 330 
PHE CB  HB3  sing N N 331 
PHE CG  CD1  doub Y N 332 
PHE CG  CD2  sing Y N 333 
PHE CD1 CE1  sing Y N 334 
PHE CD1 HD1  sing N N 335 
PHE CD2 CE2  doub Y N 336 
PHE CD2 HD2  sing N N 337 
PHE CE1 CZ   doub Y N 338 
PHE CE1 HE1  sing N N 339 
PHE CE2 CZ   sing Y N 340 
PHE CE2 HE2  sing N N 341 
PHE CZ  HZ   sing N N 342 
PHE OXT HXT  sing N N 343 
PRO N   CA   sing N N 344 
PRO N   CD   sing N N 345 
PRO N   H    sing N N 346 
PRO CA  C    sing N N 347 
PRO CA  CB   sing N N 348 
PRO CA  HA   sing N N 349 
PRO C   O    doub N N 350 
PRO C   OXT  sing N N 351 
PRO CB  CG   sing N N 352 
PRO CB  HB2  sing N N 353 
PRO CB  HB3  sing N N 354 
PRO CG  CD   sing N N 355 
PRO CG  HG2  sing N N 356 
PRO CG  HG3  sing N N 357 
PRO CD  HD2  sing N N 358 
PRO CD  HD3  sing N N 359 
PRO OXT HXT  sing N N 360 
SER N   CA   sing N N 361 
SER N   H    sing N N 362 
SER N   H2   sing N N 363 
SER CA  C    sing N N 364 
SER CA  CB   sing N N 365 
SER CA  HA   sing N N 366 
SER C   O    doub N N 367 
SER C   OXT  sing N N 368 
SER CB  OG   sing N N 369 
SER CB  HB2  sing N N 370 
SER CB  HB3  sing N N 371 
SER OG  HG   sing N N 372 
SER OXT HXT  sing N N 373 
THR N   CA   sing N N 374 
THR N   H    sing N N 375 
THR N   H2   sing N N 376 
THR CA  C    sing N N 377 
THR CA  CB   sing N N 378 
THR CA  HA   sing N N 379 
THR C   O    doub N N 380 
THR C   OXT  sing N N 381 
THR CB  OG1  sing N N 382 
THR CB  CG2  sing N N 383 
THR CB  HB   sing N N 384 
THR OG1 HG1  sing N N 385 
THR CG2 HG21 sing N N 386 
THR CG2 HG22 sing N N 387 
THR CG2 HG23 sing N N 388 
THR OXT HXT  sing N N 389 
TRP N   CA   sing N N 390 
TRP N   H    sing N N 391 
TRP N   H2   sing N N 392 
TRP CA  C    sing N N 393 
TRP CA  CB   sing N N 394 
TRP CA  HA   sing N N 395 
TRP C   O    doub N N 396 
TRP C   OXT  sing N N 397 
TRP CB  CG   sing N N 398 
TRP CB  HB2  sing N N 399 
TRP CB  HB3  sing N N 400 
TRP CG  CD1  doub Y N 401 
TRP CG  CD2  sing Y N 402 
TRP CD1 NE1  sing Y N 403 
TRP CD1 HD1  sing N N 404 
TRP CD2 CE2  doub Y N 405 
TRP CD2 CE3  sing Y N 406 
TRP NE1 CE2  sing Y N 407 
TRP NE1 HE1  sing N N 408 
TRP CE2 CZ2  sing Y N 409 
TRP CE3 CZ3  doub Y N 410 
TRP CE3 HE3  sing N N 411 
TRP CZ2 CH2  doub Y N 412 
TRP CZ2 HZ2  sing N N 413 
TRP CZ3 CH2  sing Y N 414 
TRP CZ3 HZ3  sing N N 415 
TRP CH2 HH2  sing N N 416 
TRP OXT HXT  sing N N 417 
TYR N   CA   sing N N 418 
TYR N   H    sing N N 419 
TYR N   H2   sing N N 420 
TYR CA  C    sing N N 421 
TYR CA  CB   sing N N 422 
TYR CA  HA   sing N N 423 
TYR C   O    doub N N 424 
TYR C   OXT  sing N N 425 
TYR CB  CG   sing N N 426 
TYR CB  HB2  sing N N 427 
TYR CB  HB3  sing N N 428 
TYR CG  CD1  doub Y N 429 
TYR CG  CD2  sing Y N 430 
TYR CD1 CE1  sing Y N 431 
TYR CD1 HD1  sing N N 432 
TYR CD2 CE2  doub Y N 433 
TYR CD2 HD2  sing N N 434 
TYR CE1 CZ   doub Y N 435 
TYR CE1 HE1  sing N N 436 
TYR CE2 CZ   sing Y N 437 
TYR CE2 HE2  sing N N 438 
TYR CZ  OH   sing N N 439 
TYR OH  HH   sing N N 440 
TYR OXT HXT  sing N N 441 
VAL N   CA   sing N N 442 
VAL N   H    sing N N 443 
VAL N   H2   sing N N 444 
VAL CA  C    sing N N 445 
VAL CA  CB   sing N N 446 
VAL CA  HA   sing N N 447 
VAL C   O    doub N N 448 
VAL C   OXT  sing N N 449 
VAL CB  CG1  sing N N 450 
VAL CB  CG2  sing N N 451 
VAL CB  HB   sing N N 452 
VAL CG1 HG11 sing N N 453 
VAL CG1 HG12 sing N N 454 
VAL CG1 HG13 sing N N 455 
VAL CG2 HG21 sing N N 456 
VAL CG2 HG22 sing N N 457 
VAL CG2 HG23 sing N N 458 
VAL OXT HXT  sing N N 459 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'P01 AI057788' 1 
'Robert A. Welch Foundation'                                                                      'United States' Q-1279         2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6nir 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9DAP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010274 
_atom_sites.fract_transf_matrix[1][2]   0.005932 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011864 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.022847 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 8.95735 ?       ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 7.96527 ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . SER A 1 4   ? -15.49300 -21.36900 2.63500   1.000 50.17366  ? 4   SER A N    1 
ATOM   2    C CA   . SER A 1 4   ? -15.79400 -21.73100 4.02300   1.000 57.39593  ? 4   SER A CA   1 
ATOM   3    C C    . SER A 1 4   ? -17.30500 -21.85900 4.22000   1.000 52.17353  ? 4   SER A C    1 
ATOM   4    O O    . SER A 1 4   ? -17.76600 -22.75100 4.93500   1.000 55.21888  ? 4   SER A O    1 
ATOM   5    C CB   . SER A 1 4   ? -15.21600 -20.70000 5.01000   1.000 71.94368  ? 4   SER A CB   1 
ATOM   6    O OG   . SER A 1 4   ? -15.59800 -20.97600 6.35600   1.000 66.07776  ? 4   SER A OG   1 
ATOM   7    H HA   . SER A 1 4   ? -15.39200 -22.59200 4.21900   1.000 62.27819  ? 4   SER A HA   1 
ATOM   8    H HB2  . SER A 1 4   ? -14.24800 -20.71900 4.95000   1.000 78.27819  ? 4   SER A HB2  1 
ATOM   9    H HB3  . SER A 1 4   ? -15.54200 -19.81900 4.76800   1.000 78.27819  ? 4   SER A HB3  1 
ATOM   10   H HG   . SER A 1 4   ? -15.27000 -20.40000 6.87200   1.000 71.48819  ? 4   SER A HG   1 
ATOM   11   N N    . ILE A 1 5   ? -18.06800 -20.95200 3.59800   1.000 47.67095  ? 5   ILE A N    1 
ATOM   12   C CA   . ILE A 1 5   ? -19.51900 -21.08900 3.55900   1.000 43.85783  ? 5   ILE A CA   1 
ATOM   13   C C    . ILE A 1 5   ? -19.94600 -22.28400 2.70700   1.000 38.75627  ? 5   ILE A C    1 
ATOM   14   O O    . ILE A 1 5   ? -21.04000 -22.82500 2.90900   1.000 37.68490  ? 5   ILE A O    1 
ATOM   15   C CB   . ILE A 1 5   ? -20.17100 -19.79000 3.04200   1.000 44.99740  ? 5   ILE A CB   1 
ATOM   16   C CG1  . ILE A 1 5   ? -21.66400 -19.82700 3.36900   1.000 47.15135  ? 5   ILE A CG1  1 
ATOM   17   C CG2  . ILE A 1 5   ? -19.90100 -19.61900 1.55400   1.000 59.52719  ? 5   ILE A CG2  1 
ATOM   18   C CD1  . ILE A 1 5   ? -22.41400 -18.54200 3.13600   1.000 64.12903  ? 5   ILE A CD1  1 
ATOM   19   H H    . ILE A 1 5   ? -17.76700 -20.25400 3.19500   1.000 57.28819  ? 5   ILE A H    1 
ATOM   20   H HA   . ILE A 1 5   ? -19.83900 -21.24200 4.46200   1.000 53.94819  ? 5   ILE A HA   1 
ATOM   21   H HB   . ILE A 1 5   ? -19.77400 -19.04000 3.51200   1.000 54.88819  ? 5   ILE A HB   1 
ATOM   22   H HG12 . ILE A 1 5   ? -22.08200 -20.51000 2.82200   1.000 58.53819  ? 5   ILE A HG12 1 
ATOM   23   H HG13 . ILE A 1 5   ? -21.76700 -20.05300 4.30600   1.000 58.53819  ? 5   ILE A HG13 1 
ATOM   24   H HG21 . ILE A 1 5   ? -20.08300 -18.69900 1.30500   1.000 71.92819  ? 5   ILE A HG21 1 
ATOM   25   H HG22 . ILE A 1 5   ? -18.97200 -19.83200 1.37600   1.000 71.92819  ? 5   ILE A HG22 1 
ATOM   26   H HG23 . ILE A 1 5   ? -20.47900 -20.21700 1.05500   1.000 71.92819  ? 5   ILE A HG23 1 
ATOM   27   H HD11 . ILE A 1 5   ? -23.32100 -18.64300 3.46400   1.000 78.40819  ? 5   ILE A HD11 1 
ATOM   28   H HD12 . ILE A 1 5   ? -21.96700 -17.82600 3.61400   1.000 78.40819  ? 5   ILE A HD12 1 
ATOM   29   H HD13 . ILE A 1 5   ? -22.42300 -18.35000 2.18500   1.000 78.40819  ? 5   ILE A HD13 1 
ATOM   30   N N    . TRP A 1 6   ? -19.10500 -22.71500 1.75800   1.000 44.96298  ? 6   TRP A N    1 
ATOM   31   C CA   . TRP A 1 6   ? -19.38100 -23.93300 1.00100   1.000 42.93651  ? 6   TRP A CA   1 
ATOM   32   C C    . TRP A 1 6   ? -19.22400 -25.17900 1.86000   1.000 38.48269  ? 6   TRP A C    1 
ATOM   33   O O    . TRP A 1 6   ? -19.91200 -26.17900 1.63400   1.000 42.22615  ? 6   TRP A O    1 
ATOM   34   C CB   . TRP A 1 6   ? -18.45400 -24.01400 -0.21300  1.000 36.76750  ? 6   TRP A CB   1 
ATOM   35   C CG   . TRP A 1 6   ? -18.79600 -23.01200 -1.28500  1.000 38.13456  ? 6   TRP A CG   1 
ATOM   36   C CD1  . TRP A 1 6   ? -18.19800 -21.80900 -1.51000  1.000 41.28168  ? 6   TRP A CD1  1 
ATOM   37   C CD2  . TRP A 1 6   ? -19.82100 -23.14000 -2.27200  1.000 38.83555  ? 6   TRP A CD2  1 
ATOM   38   N NE1  . TRP A 1 6   ? -18.79500 -21.17500 -2.57500  1.000 44.72503  ? 6   TRP A NE1  1 
ATOM   39   C CE2  . TRP A 1 6   ? -19.79100 -21.97700 -3.06500  1.000 39.23448  ? 6   TRP A CE2  1 
ATOM   40   C CE3  . TRP A 1 6   ? -20.76000 -24.13000 -2.56200  1.000 36.37335  ? 6   TRP A CE3  1 
ATOM   41   C CZ2  . TRP A 1 6   ? -20.66500 -21.77700 -4.13000  1.000 41.06775  ? 6   TRP A CZ2  1 
ATOM   42   C CZ3  . TRP A 1 6   ? -21.62500 -23.93300 -3.61400  1.000 44.31145  ? 6   TRP A CZ3  1 
ATOM   43   C CH2  . TRP A 1 6   ? -21.57500 -22.76500 -4.38700  1.000 49.90574  ? 6   TRP A CH2  1 
ATOM   44   H H    . TRP A 1 6   ? -18.37400 -22.32000 1.53800   1.000 56.58819  ? 6   TRP A H    1 
ATOM   45   H HA   . TRP A 1 6   ? -20.29500 -23.90400 0.67900   1.000 54.85819  ? 6   TRP A HA   1 
ATOM   46   H HB2  . TRP A 1 6   ? -17.54300 -23.84500 0.07400   1.000 46.47819  ? 6   TRP A HB2  1 
ATOM   47   H HB3  . TRP A 1 6   ? -18.52000 -24.90100 -0.60100  1.000 46.47819  ? 6   TRP A HB3  1 
ATOM   48   H HD1  . TRP A 1 6   ? -17.49500 -21.46200 -1.01000  1.000 50.03819  ? 6   TRP A HD1  1 
ATOM   49   H HE1  . TRP A 1 6   ? -18.57100 -20.40600 -2.88900  1.000 53.75819  ? 6   TRP A HE1  1 
ATOM   50   H HE3  . TRP A 1 6   ? -20.80000 -24.90800 -2.05500  1.000 46.67819  ? 6   TRP A HE3  1 
ATOM   51   H HZ2  . TRP A 1 6   ? -20.63400 -21.00200 -4.64300  1.000 50.18819  ? 6   TRP A HZ2  1 
ATOM   52   H HZ3  . TRP A 1 6   ? -22.25500 -24.58700 -3.81500  1.000 56.05819  ? 6   TRP A HZ3  1 
ATOM   53   H HH2  . TRP A 1 6   ? -22.17300 -22.66000 -5.09200  1.000 61.71819  ? 6   TRP A HH2  1 
ATOM   54   N N    . SER A 1 7   ? -18.34000 -25.13400 2.85200   1.000 49.06881  ? 7   SER A N    1 
ATOM   55   C CA   . SER A 1 7   ? -18.13000 -26.26300 3.75000   1.000 38.86718  ? 7   SER A CA   1 
ATOM   56   C C    . SER A 1 7   ? -19.36400 -26.54100 4.60100   1.000 41.37532  ? 7   SER A C    1 
ATOM   57   O O    . SER A 1 7   ? -19.42600 -27.54700 5.32200   1.000 40.93158  ? 7   SER A O    1 
ATOM   58   C CB   . SER A 1 7   ? -16.93100 -25.98800 4.65500   1.000 40.31328  ? 7   SER A CB   1 
ATOM   59   O OG   . SER A 1 7   ? -17.27500 -25.16000 5.75700   1.000 43.07322  ? 7   SER A OG   1 
ATOM   60   H H    . SER A 1 7   ? -17.84400 -24.45300 3.02700   1.000 59.54819  ? 7   SER A H    1 
ATOM   61   H HA   . SER A 1 7   ? -17.93900 -27.05600 3.22600   1.000 47.56819  ? 7   SER A HA   1 
ATOM   62   H HB2  . SER A 1 7   ? -16.59500 -26.83300 4.99300   1.000 48.19819  ? 7   SER A HB2  1 
ATOM   63   H HB3  . SER A 1 7   ? -16.24300 -25.54500 4.13500   1.000 48.19819  ? 7   SER A HB3  1 
ATOM   64   H HG   . SER A 1 7   ? -17.56800 -24.42300 5.48200   1.000 51.25819  ? 7   SER A HG   1 
ATOM   65   N N    . ARG A 1 8   ? -20.34200 -25.63900 4.53100   1.000 42.32547  ? 8   ARG A N    1 
ATOM   66   C CA   . ARG A 1 8   ? -21.59800 -25.78300 5.24500   1.000 36.45169  ? 8   ARG A CA   1 
ATOM   67   C C    . ARG A 1 8   ? -22.63900 -26.54600 4.43900   1.000 36.35621  ? 8   ARG A C    1 
ATOM   68   O O    . ARG A 1 8   ? -23.62100 -27.01400 5.02300   1.000 35.48751  ? 8   ARG A O    1 
ATOM   69   C CB   . ARG A 1 8   ? -22.14300 -24.40200 5.62800   1.000 38.16894  ? 8   ARG A CB   1 
ATOM   70   C CG   . ARG A 1 8   ? -21.18200 -23.58300 6.48800   1.000 43.35029  ? 8   ARG A CG   1 
ATOM   71   C CD   . ARG A 1 8   ? -21.52600 -22.11500 6.48700   1.000 43.36369  ? 8   ARG A CD   1 
ATOM   72   N NE   . ARG A 1 8   ? -22.57100 -21.83400 7.45800   1.000 45.52815  ? 8   ARG A NE   1 
ATOM   73   C CZ   . ARG A 1 8   ? -22.43100 -21.04100 8.50900   1.000 38.98248  ? 8   ARG A CZ   1 
ATOM   74   N NH1  . ARG A 1 8   ? -21.32400 -20.35600 8.71600   1.000 44.19286  ? 8   ARG A NH1  1 
ATOM   75   N NH2  . ARG A 1 8   ? -23.44000 -20.92300 9.36400   1.000 57.21623  ? 8   ARG A NH2  1 
ATOM   76   H H    . ARG A 1 8   ? -20.29900 -24.91400 4.07300   1.000 53.85819  ? 8   ARG A H    1 
ATOM   77   H HA   . ARG A 1 8   ? -21.43800 -26.27600 6.06500   1.000 47.52819  ? 8   ARG A HA   1 
ATOM   78   H HB2  . ARG A 1 8   ? -22.31900 -23.90200 4.81600   1.000 49.28819  ? 8   ARG A HB2  1 
ATOM   79   H HB3  . ARG A 1 8   ? -22.96600 -24.51700 6.12900   1.000 49.28819  ? 8   ARG A HB3  1 
ATOM   80   H HG2  . ARG A 1 8   ? -21.22600 -23.90200 7.40300   1.000 54.31819  ? 8   ARG A HG2  1 
ATOM   81   H HG3  . ARG A 1 8   ? -20.28000 -23.68000 6.14400   1.000 54.31819  ? 8   ARG A HG3  1 
ATOM   82   H HD2  . ARG A 1 8   ? -20.73000 -21.60500 6.69400   1.000 53.73819  ? 8   ARG A HD2  1 
ATOM   83   H HD3  . ARG A 1 8   ? -21.85800 -21.86800 5.61000   1.000 53.73819  ? 8   ARG A HD3  1 
ATOM   84   H HE   . ARG A 1 8   ? -23.33600 -22.21000 7.34100   1.000 56.43819  ? 8   ARG A HE   1 
ATOM   85   H HH11 . ARG A 1 8   ? -20.66000 -20.41800 8.17600   1.000 52.43819  ? 8   ARG A HH11 1 
ATOM   86   H HH12 . ARG A 1 8   ? -21.26400 -19.84600 9.40600   1.000 52.43819  ? 8   ARG A HH12 1 
ATOM   87   H HH21 . ARG A 1 8   ? -24.16700 -21.36300 9.23400   1.000 69.41819  ? 8   ARG A HH21 1 
ATOM   88   H HH22 . ARG A 1 8   ? -23.36600 -20.40600 10.04800  1.000 69.41819  ? 8   ARG A HH22 1 
ATOM   89   N N    . ILE A 1 9   ? -22.44700 -26.69300 3.12400   1.000 41.99320  ? 9   ILE A N    1 
ATOM   90   C CA   . ILE A 1 9   ? -23.31300 -27.52600 2.29000   1.000 39.42400  ? 9   ILE A CA   1 
ATOM   91   C C    . ILE A 1 9   ? -22.76400 -28.94800 2.29000   1.000 39.07812  ? 9   ILE A C    1 
ATOM   92   O O    . ILE A 1 9   ? -21.58900 -29.17100 1.97600   1.000 39.23353  ? 9   ILE A O    1 
ATOM   93   C CB   . ILE A 1 9   ? -23.41100 -26.96100 0.86200   1.000 32.11019  ? 9   ILE A CB   1 
ATOM   94   C CG1  . ILE A 1 9   ? -24.11700 -25.59800 0.89400   1.000 32.85708  ? 9   ILE A CG1  1 
ATOM   95   C CG2  . ILE A 1 9   ? -24.13100 -27.95900 -0.05200  1.000 45.93993  ? 9   ILE A CG2  1 
ATOM   96   C CD1  . ILE A 1 9   ? -23.42900 -24.52500 0.08000   1.000 38.95621  ? 9   ILE A CD1  1 
ATOM   97   H H    . ILE A 1 9   ? -21.81100 -26.31300 2.68700   1.000 53.56819  ? 9   ILE A H    1 
ATOM   98   H HA   . ILE A 1 9   ? -24.20400 -27.54100 2.67100   1.000 51.01819  ? 9   ILE A HA   1 
ATOM   99   H HB   . ILE A 1 9   ? -22.51200 -26.83100 0.52300   1.000 41.91819  ? 9   ILE A HB   1 
ATOM   100  H HG12 . ILE A 1 9   ? -25.01500 -25.70400 0.54400   1.000 42.82819  ? 9   ILE A HG12 1 
ATOM   101  H HG13 . ILE A 1 9   ? -24.15700 -25.29000 1.81100   1.000 42.82819  ? 9   ILE A HG13 1 
ATOM   102  H HG21 . ILE A 1 9   ? -24.42000 -27.49700 -0.85400  1.000 58.71819  ? 9   ILE A HG21 1 
ATOM   103  H HG22 . ILE A 1 9   ? -23.52000 -28.67500 -0.28700  1.000 58.71819  ? 9   ILE A HG22 1 
ATOM   104  H HG23 . ILE A 1 9   ? -24.90100 -28.31800 0.41700   1.000 58.71819  ? 9   ILE A HG23 1 
ATOM   105  H HD11 . ILE A 1 9   ? -22.53600 -24.38700 0.43100   1.000 49.24819  ? 9   ILE A HD11 1 
ATOM   106  H HD12 . ILE A 1 9   ? -23.38100 -24.81300 -0.84500  1.000 49.24819  ? 9   ILE A HD12 1 
ATOM   107  H HD13 . ILE A 1 9   ? -23.94100 -23.70300 0.14500   1.000 49.24819  ? 9   ILE A HD13 1 
ATOM   108  N N    . VAL A 1 10  ? -23.60300 -29.91400 2.66200   1.000 41.39953  ? 10  VAL A N    1 
ATOM   109  C CA   . VAL A 1 10  ? -23.17200 -31.29400 2.85800   1.000 41.15657  ? 10  VAL A CA   1 
ATOM   110  C C    . VAL A 1 10  ? -24.11900 -32.23000 2.12300   1.000 41.65197  ? 10  VAL A C    1 
ATOM   111  O O    . VAL A 1 10  ? -25.32800 -31.98000 2.04500   1.000 44.86097  ? 10  VAL A O    1 
ATOM   112  C CB   . VAL A 1 10  ? -23.10500 -31.66500 4.35700   1.000 39.27844  ? 10  VAL A CB   1 
ATOM   113  C CG1  . VAL A 1 10  ? -22.44300 -33.02900 4.54500   1.000 42.64341  ? 10  VAL A CG1  1 
ATOM   114  C CG2  . VAL A 1 10  ? -22.36300 -30.59000 5.11900   1.000 52.19851  ? 10  VAL A CG2  1 
ATOM   115  H H    . VAL A 1 10  ? -24.44100 -29.79100 2.80900   1.000 49.62819  ? 10  VAL A H    1 
ATOM   116  H HA   . VAL A 1 10  ? -22.28600 -31.40900 2.48100   1.000 49.11819  ? 10  VAL A HA   1 
ATOM   117  H HB   . VAL A 1 10  ? -24.00700 -31.71700 4.71100   1.000 46.85819  ? 10  VAL A HB   1 
ATOM   118  H HG11 . VAL A 1 10  ? -22.38300 -33.21700 5.49400   1.000 50.41819  ? 10  VAL A HG11 1 
ATOM   119  H HG12 . VAL A 1 10  ? -22.98100 -33.70700 4.10700   1.000 50.41819  ? 10  VAL A HG12 1 
ATOM   120  H HG13 . VAL A 1 10  ? -21.55500 -33.00600 4.15500   1.000 50.41819  ? 10  VAL A HG13 1 
ATOM   121  H HG21 . VAL A 1 10  ? -22.27300 -30.86900 6.04200   1.000 62.01819  ? 10  VAL A HG21 1 
ATOM   122  H HG22 . VAL A 1 10  ? -21.48700 -30.46800 4.72200   1.000 62.01819  ? 10  VAL A HG22 1 
ATOM   123  H HG23 . VAL A 1 10  ? -22.86600 -29.76200 5.07400   1.000 62.01819  ? 10  VAL A HG23 1 
ATOM   124  N N    . ASN A 1 11  ? -23.55400 -33.28100 1.54100   1.000 50.57049  ? 11  ASN A N    1 
ATOM   125  C CA   . ASN A 1 11  ? -24.33500 -34.40800 1.05800   1.000 48.91084  ? 11  ASN A CA   1 
ATOM   126  C C    . ASN A 1 11  ? -25.26100 -34.89500 2.16100   1.000 41.76914  ? 11  ASN A C    1 
ATOM   127  O O    . ASN A 1 11  ? -24.81100 -35.24400 3.25500   1.000 42.54505  ? 11  ASN A O    1 
ATOM   128  C CB   . ASN A 1 11  ? -23.39400 -35.52700 0.61200   1.000 50.69656  ? 11  ASN A CB   1 
ATOM   129  C CG   . ASN A 1 11  ? -24.05600 -36.88800 0.62900   1.000 59.60578  ? 11  ASN A CG   1 
ATOM   130  O OD1  . ASN A 1 11  ? -25.26400 -37.00000 0.47300   1.000 68.27938  ? 11  ASN A OD1  1 
ATOM   131  N ND2  . ASN A 1 11  ? -23.26600 -37.93000 0.83900   1.000 74.29754  ? 11  ASN A ND2  1 
ATOM   132  H H    . ASN A 1 11  ? -22.70800 -33.36500 1.41300   1.000 58.79819  ? 11  ASN A H    1 
ATOM   133  H HA   . ASN A 1 11  ? -24.87300 -34.13200 0.29900   1.000 56.62819  ? 11  ASN A HA   1 
ATOM   134  H HB2  . ASN A 1 11  ? -23.09800 -35.34900 -0.29400  1.000 57.90819  ? 11  ASN A HB2  1 
ATOM   135  H HB3  . ASN A 1 11  ? -22.63200 -35.55700 1.21100   1.000 57.90819  ? 11  ASN A HB3  1 
ATOM   136  H HD21 . ASN A 1 11  ? -22.42100 -37.81400 0.94800   1.000 85.11819  ? 11  ASN A HD21 1 
ATOM   137  H HD22 . ASN A 1 11  ? -23.59700 -38.72300 0.85900   1.000 85.11819  ? 11  ASN A HD22 1 
ATOM   138  N N    . PHE A 1 12  ? -26.55500 -34.90500 1.87400   1.000 43.68497  ? 12  PHE A N    1 
ATOM   139  C CA   . PHE A 1 12  ? -27.57100 -35.43000 2.77300   1.000 41.28415  ? 12  PHE A CA   1 
ATOM   140  C C    . PHE A 1 12  ? -28.57300 -36.18200 1.91200   1.000 39.85074  ? 12  PHE A C    1 
ATOM   141  O O    . PHE A 1 12  ? -29.17700 -35.59200 1.01000   1.000 39.89266  ? 12  PHE A O    1 
ATOM   142  C CB   . PHE A 1 12  ? -28.23700 -34.29600 3.55200   1.000 36.75945  ? 12  PHE A CB   1 
ATOM   143  C CG   . PHE A 1 12  ? -28.87600 -34.73600 4.83100   1.000 32.39353  ? 12  PHE A CG   1 
ATOM   144  C CD1  . PHE A 1 12  ? -28.10400 -35.19900 5.86400   1.000 29.55567  ? 12  PHE A CD1  1 
ATOM   145  C CD2  . PHE A 1 12  ? -30.23900 -34.68300 5.00900   1.000 37.73633  ? 12  PHE A CD2  1 
ATOM   146  C CE1  . PHE A 1 12  ? -28.66600 -35.61200 7.04900   1.000 26.23182  ? 12  PHE A CE1  1 
ATOM   147  C CE2  . PHE A 1 12  ? -30.80200 -35.09400 6.20800   1.000 38.00979  ? 12  PHE A CE2  1 
ATOM   148  C CZ   . PHE A 1 12  ? -30.00300 -35.55700 7.22400   1.000 26.18202  ? 12  PHE A CZ   1 
ATOM   149  H H    . PHE A 1 12  ? -26.87900 -34.60200 1.13800   1.000 57.95819  ? 12  PHE A H    1 
ATOM   150  H HA   . PHE A 1 12  ? -27.16800 -36.05100 3.39900   1.000 55.18819  ? 12  PHE A HA   1 
ATOM   151  H HB2  . PHE A 1 12  ? -27.56600 -33.63000 3.77000   1.000 50.35819  ? 12  PHE A HB2  1 
ATOM   152  H HB3  . PHE A 1 12  ? -28.92700 -33.89900 2.99700   1.000 50.35819  ? 12  PHE A HB3  1 
ATOM   153  H HD1  . PHE A 1 12  ? -27.18100 -35.24200 5.75900   1.000 41.26819  ? 12  PHE A HD1  1 
ATOM   154  H HD2  . PHE A 1 12  ? -30.78400 -34.36900 4.32400   1.000 51.48819  ? 12  PHE A HD2  1 
ATOM   155  H HE1  . PHE A 1 12  ? -28.12200 -35.92300 7.73600   1.000 36.90819  ? 12  PHE A HE1  1 
ATOM   156  H HE2  . PHE A 1 12  ? -31.72400 -35.05800 6.32400   1.000 51.47819  ? 12  PHE A HE2  1 
ATOM   157  H HZ   . PHE A 1 12  ? -30.38100 -35.83500 8.02700   1.000 36.84819  ? 12  PHE A HZ   1 
ATOM   158  N N    . GLY A 1 13  ? -28.71700 -37.48200 2.14900   1.000 36.11695  ? 13  GLY A N    1 
ATOM   159  C CA   . GLY A 1 13  ? -29.65400 -38.26800 1.36300   1.000 29.94408  ? 13  GLY A CA   1 
ATOM   160  C C    . GLY A 1 13  ? -29.45000 -38.10000 -0.12800  1.000 33.01180  ? 13  GLY A C    1 
ATOM   161  O O    . GLY A 1 13  ? -28.31900 -38.04200 -0.62500  1.000 35.38870  ? 13  GLY A O    1 
ATOM   162  H H    . GLY A 1 13  ? -28.29000 -37.92500 2.75000   1.000 50.72819  ? 13  GLY A H    1 
ATOM   163  H HA2  . GLY A 1 13  ? -29.54600 -39.20700 1.57900   1.000 42.63819  ? 13  GLY A HA2  1 
ATOM   164  H HA3  . GLY A 1 13  ? -30.56000 -38.00500 1.58300   1.000 42.63819  ? 13  GLY A HA3  1 
ATOM   165  N N    . SER A 1 14  ? -30.56400 -38.02300 -0.85800  1.000 35.59599  ? 14  SER A N    1 
ATOM   166  C CA   . SER A 1 14  ? -30.55200 -37.83000 -2.30200  1.000 40.53674  ? 14  SER A CA   1 
ATOM   167  C C    . SER A 1 14  ? -30.29600 -36.38300 -2.69400  1.000 46.88252  ? 14  SER A C    1 
ATOM   168  O O    . SER A 1 14  ? -30.40600 -36.03600 -3.87700  1.000 48.43740  ? 14  SER A O    1 
ATOM   169  C CB   . SER A 1 14  ? -31.87900 -38.30300 -2.90300  1.000 39.99199  ? 14  SER A CB   1 
ATOM   170  O OG   . SER A 1 14  ? -32.98900 -37.62200 -2.34100  1.000 45.56306  ? 14  SER A OG   1 
ATOM   171  H H    . SER A 1 14  ? -31.35600 -38.08200 -0.52800  1.000 44.20819  ? 14  SER A H    1 
ATOM   172  H HA   . SER A 1 14  ? -29.84300 -38.37100 -2.68400  1.000 49.44819  ? 14  SER A HA   1 
ATOM   173  H HB2  . SER A 1 14  ? -31.86400 -38.14000 -3.85900  1.000 47.91819  ? 14  SER A HB2  1 
ATOM   174  H HB3  . SER A 1 14  ? -31.97700 -39.25300 -2.73300  1.000 47.91819  ? 14  SER A HB3  1 
ATOM   175  H HG   . SER A 1 14  ? -33.70200 -37.90000 -2.68700  1.000 55.28819  ? 14  SER A HG   1 
ATOM   176  N N    . GLY A 1 15  ? -29.96600 -35.53400 -1.74000  1.000 41.31658  ? 15  GLY A N    1 
ATOM   177  C CA   . GLY A 1 15  ? -29.73300 -34.12500 -2.00900  1.000 42.60347  ? 15  GLY A CA   1 
ATOM   178  C C    . GLY A 1 15  ? -28.74800 -33.56400 -1.03800  1.000 41.41997  ? 15  GLY A C    1 
ATOM   179  O O    . GLY A 1 15  ? -27.71800 -34.19400 -0.75600  1.000 36.30043  ? 15  GLY A O    1 
ATOM   180  H H    . GLY A 1 15  ? -29.86100 -35.74800 -0.91500  1.000 50.95819  ? 15  GLY A H    1 
ATOM   181  H HA2  . GLY A 1 15  ? -29.38300 -34.01500 -2.90700  1.000 52.99819  ? 15  GLY A HA2  1 
ATOM   182  H HA3  . GLY A 1 15  ? -30.56400 -33.63100 -1.93500  1.000 52.99819  ? 15  GLY A HA3  1 
ATOM   183  N N    . TRP A 1 16  ? -29.03900 -32.37800 -0.51500  1.000 39.45474  ? 16  TRP A N    1 
ATOM   184  C CA   . TRP A 1 16  ? -28.03800 -31.63800 0.23500   1.000 35.90639  ? 16  TRP A CA   1 
ATOM   185  C C    . TRP A 1 16  ? -28.67500 -30.98300 1.45200   1.000 38.08450  ? 16  TRP A C    1 
ATOM   186  O O    . TRP A 1 16  ? -29.90000 -30.90300 1.57500   1.000 39.05775  ? 16  TRP A O    1 
ATOM   187  C CB   . TRP A 1 16  ? -27.35400 -30.58100 -0.65500  1.000 41.96235  ? 16  TRP A CB   1 
ATOM   188  C CG   . TRP A 1 16  ? -26.74600 -31.14600 -1.90400  1.000 37.89825  ? 16  TRP A CG   1 
ATOM   189  C CD1  . TRP A 1 16  ? -27.38000 -31.38800 -3.08500  1.000 35.35607  ? 16  TRP A CD1  1 
ATOM   190  C CD2  . TRP A 1 16  ? -25.38400 -31.54000 -2.08900  1.000 39.66858  ? 16  TRP A CD2  1 
ATOM   191  N NE1  . TRP A 1 16  ? -26.50000 -31.91100 -3.99600  1.000 40.89321  ? 16  TRP A NE1  1 
ATOM   192  C CE2  . TRP A 1 16  ? -25.26600 -32.01100 -3.41000  1.000 36.68763  ? 16  TRP A CE2  1 
ATOM   193  C CE3  . TRP A 1 16  ? -24.25000 -31.52800 -1.27100  1.000 37.94230  ? 16  TRP A CE3  1 
ATOM   194  C CZ2  . TRP A 1 16  ? -24.06600 -32.48000 -3.92400  1.000 37.03499  ? 16  TRP A CZ2  1 
ATOM   195  C CZ3  . TRP A 1 16  ? -23.06000 -32.00200 -1.78500  1.000 34.19523  ? 16  TRP A CZ3  1 
ATOM   196  C CH2  . TRP A 1 16  ? -22.97800 -32.46700 -3.09800  1.000 37.09947  ? 16  TRP A CH2  1 
ATOM   197  H H    . TRP A 1 16  ? -29.80100 -31.98500 -0.58000  1.000 49.46819  ? 16  TRP A H    1 
ATOM   198  H HA   . TRP A 1 16  ? -27.35600 -32.25000 0.55000   1.000 45.54819  ? 16  TRP A HA   1 
ATOM   199  H HB2  . TRP A 1 16  ? -28.01300 -29.92000 -0.91900  1.000 52.51819  ? 16  TRP A HB2  1 
ATOM   200  H HB3  . TRP A 1 16  ? -26.64600 -30.15500 -0.14700  1.000 52.51819  ? 16  TRP A HB3  1 
ATOM   201  H HD1  . TRP A 1 16  ? -28.28100 -31.22700 -3.24800  1.000 43.16819  ? 16  TRP A HD1  1 
ATOM   202  H HE1  . TRP A 1 16  ? -26.69100 -32.13800 -4.80300  1.000 48.87819  ? 16  TRP A HE1  1 
ATOM   203  H HE3  . TRP A 1 16  ? -24.30100 -31.22600 -0.39300  1.000 46.40819  ? 16  TRP A HE3  1 
ATOM   204  H HZ2  . TRP A 1 16  ? -24.00400 -32.78900 -4.79900  1.000 43.45819  ? 16  TRP A HZ2  1 
ATOM   205  H HZ3  . TRP A 1 16  ? -22.29900 -32.00300 -1.25100  1.000 41.10819  ? 16  TRP A HZ3  1 
ATOM   206  H HH2  . TRP A 1 16  ? -22.16100 -32.77200 -3.42100  1.000 43.69819  ? 16  TRP A HH2  1 
ATOM   207  N N    . GLY A 1 17  ? -27.81000 -30.51700 2.35900   1.000 36.99517  ? 17  GLY A N    1 
ATOM   208  C CA   . GLY A 1 17  ? -28.22700 -29.77900 3.53800   1.000 29.77931  ? 17  GLY A CA   1 
ATOM   209  C C    . GLY A 1 17  ? -27.18400 -28.73700 3.88600   1.000 33.25187  ? 17  GLY A C    1 
ATOM   210  O O    . GLY A 1 17  ? -26.02900 -28.82200 3.45700   1.000 38.41270  ? 17  GLY A O    1 
ATOM   211  H H    . GLY A 1 17  ? -26.95800 -30.62200 2.30500   1.000 47.71819  ? 17  GLY A H    1 
ATOM   212  H HA2  . GLY A 1 17  ? -29.06300 -29.32400 3.35400   1.000 39.28819  ? 17  GLY A HA2  1 
ATOM   213  H HA3  . GLY A 1 17  ? -28.36500 -30.37900 4.28000   1.000 39.28819  ? 17  GLY A HA3  1 
ATOM   214  N N    . PHE A 1 18  ? -27.60000 -27.74400 4.67100   1.000 35.36380  ? 18  PHE A N    1 
ATOM   215  C CA   . PHE A 1 18  ? -26.78300 -26.56900 4.96200   1.000 31.59444  ? 18  PHE A CA   1 
ATOM   216  C C    . PHE A 1 18  ? -26.72300 -26.36400 6.46900   1.000 34.31677  ? 18  PHE A C    1 
ATOM   217  O O    . PHE A 1 18  ? -27.75600 -26.42800 7.14200   1.000 30.62001  ? 18  PHE A O    1 
ATOM   218  C CB   . PHE A 1 18  ? -27.36800 -25.33200 4.26000   1.000 31.28554  ? 18  PHE A CB   1 
ATOM   219  C CG   . PHE A 1 18  ? -26.63600 -24.05400 4.54500   1.000 38.60526  ? 18  PHE A CG   1 
ATOM   220  C CD1  . PHE A 1 18  ? -25.42300 -23.77700 3.93800   1.000 39.79878  ? 18  PHE A CD1  1 
ATOM   221  C CD2  . PHE A 1 18  ? -27.17800 -23.11100 5.39000   1.000 37.71724  ? 18  PHE A CD2  1 
ATOM   222  C CE1  . PHE A 1 18  ? -24.75400 -22.59100 4.19600   1.000 35.41602  ? 18  PHE A CE1  1 
ATOM   223  C CE2  . PHE A 1 18  ? -26.52000 -21.92600 5.63900   1.000 37.35597  ? 18  PHE A CE2  1 
ATOM   224  C CZ   . PHE A 1 18  ? -25.30300 -21.67100 5.05100   1.000 33.96659  ? 18  PHE A CZ   1 
ATOM   225  H H    . PHE A 1 18  ? -28.37000 -27.72900 5.05500   1.000 47.60819  ? 18  PHE A H    1 
ATOM   226  H HA   . PHE A 1 18  ? -25.88400 -26.70900 4.63200   1.000 42.63819  ? 18  PHE A HA   1 
ATOM   227  H HB2  . PHE A 1 18  ? -27.34300 -25.47800 3.30100   1.000 42.20819  ? 18  PHE A HB2  1 
ATOM   228  H HB3  . PHE A 1 18  ? -28.28700 -25.21600 4.54900   1.000 42.20819  ? 18  PHE A HB3  1 
ATOM   229  H HD1  . PHE A 1 18  ? -25.04500 -24.40200 3.36500   1.000 51.22819  ? 18  PHE A HD1  1 
ATOM   230  H HD2  . PHE A 1 18  ? -27.99700 -23.27600 5.79800   1.000 48.88819  ? 18  PHE A HD2  1 
ATOM   231  H HE1  . PHE A 1 18  ? -23.93500 -22.42000 3.79000   1.000 45.11819  ? 18  PHE A HE1  1 
ATOM   232  H HE2  . PHE A 1 18  ? -26.89200 -21.30300 6.22100   1.000 47.57819  ? 18  PHE A HE2  1 
ATOM   233  H HZ   . PHE A 1 18  ? -24.86100 -20.87100 5.22100   1.000 42.99819  ? 18  PHE A HZ   1 
ATOM   234  N N    . TRP A 1 19  ? -25.51400 -26.13800 6.99700   1.000 37.00053  ? 19  TRP A N    1 
ATOM   235  C CA   . TRP A 1 19  ? -25.29700 -25.94500 8.43400   1.000 35.06809  ? 19  TRP A CA   1 
ATOM   236  C C    . TRP A 1 19  ? -25.51000 -24.46800 8.74700   1.000 37.72484  ? 19  TRP A C    1 
ATOM   237  O O    . TRP A 1 19  ? -24.62700 -23.63600 8.53800   1.000 36.64619  ? 19  TRP A O    1 
ATOM   238  C CB   . TRP A 1 19  ? -23.89700 -26.39100 8.84800   1.000 37.00792  ? 19  TRP A CB   1 
ATOM   239  C CG   . TRP A 1 19  ? -23.72000 -27.86400 9.03100   1.000 37.04300  ? 19  TRP A CG   1 
ATOM   240  C CD1  . TRP A 1 19  ? -23.02800 -28.69900 8.21600   1.000 35.57077  ? 19  TRP A CD1  1 
ATOM   241  C CD2  . TRP A 1 19  ? -24.23700 -28.67700 10.09700  1.000 33.67990  ? 19  TRP A CD2  1 
ATOM   242  N NE1  . TRP A 1 19  ? -23.07400 -29.98100 8.70100   1.000 39.19928  ? 19  TRP A NE1  1 
ATOM   243  C CE2  . TRP A 1 19  ? -23.81700 -29.99700 9.85200   1.000 39.30079  ? 19  TRP A CE2  1 
ATOM   244  C CE3  . TRP A 1 19  ? -25.01300 -28.41600 11.23000  1.000 39.35572  ? 19  TRP A CE3  1 
ATOM   245  C CZ2  . TRP A 1 19  ? -24.15100 -31.05500 10.69500  1.000 37.95891  ? 19  TRP A CZ2  1 
ATOM   246  C CZ3  . TRP A 1 19  ? -25.34600 -29.46700 12.06500  1.000 43.04744  ? 19  TRP A CZ3  1 
ATOM   247  C CH2  . TRP A 1 19  ? -24.91100 -30.77000 11.79600  1.000 35.00713  ? 19  TRP A CH2  1 
ATOM   248  H H    . TRP A 1 19  ? -24.79100 -26.09100 6.53300   1.000 47.46819  ? 19  TRP A H    1 
ATOM   249  H HA   . TRP A 1 19  ? -25.94700 -26.46400 8.93400   1.000 44.44819  ? 19  TRP A HA   1 
ATOM   250  H HB2  . TRP A 1 19  ? -23.27000 -26.10500 8.16600   1.000 46.11819  ? 19  TRP A HB2  1 
ATOM   251  H HB3  . TRP A 1 19  ? -23.67600 -25.96400 9.69100   1.000 46.11819  ? 19  TRP A HB3  1 
ATOM   252  H HD1  . TRP A 1 19  ? -22.58200 -28.43900 7.44300   1.000 44.79819  ? 19  TRP A HD1  1 
ATOM   253  H HE1  . TRP A 1 19  ? -22.70700 -30.66700 8.33400   1.000 49.09819  ? 19  TRP A HE1  1 
ATOM   254  H HE3  . TRP A 1 19  ? -25.30900 -27.55400 11.41300  1.000 48.42819  ? 19  TRP A HE3  1 
ATOM   255  H HZ2  . TRP A 1 19  ? -23.86100 -31.92100 10.52000  1.000 46.99819  ? 19  TRP A HZ2  1 
ATOM   256  H HZ3  . TRP A 1 19  ? -25.86300 -29.30400 12.82100  1.000 52.50819  ? 19  TRP A HZ3  1 
ATOM   257  H HH2  . TRP A 1 19  ? -25.14600 -31.45700 12.37700  1.000 42.97819  ? 19  TRP A HH2  1 
ATOM   258  N N    . VAL A 1 20  ? -26.70000 -24.13200 9.25100   1.000 45.55449  ? 20  VAL A N    1 
ATOM   259  C CA   . VAL A 1 20  ? -26.98300 -22.74000 9.60100   1.000 44.38387  ? 20  VAL A CA   1 
ATOM   260  C C    . VAL A 1 20  ? -26.16200 -22.32500 10.81100  1.000 46.12054  ? 20  VAL A C    1 
ATOM   261  O O    . VAL A 1 20  ? -25.64600 -21.20100 10.87900  1.000 52.65820  ? 20  VAL A O    1 
ATOM   262  C CB   . VAL A 1 20  ? -28.49000 -22.54800 9.85000   1.000 42.48214  ? 20  VAL A CB   1 
ATOM   263  C CG1  . VAL A 1 20  ? -28.77500 -21.12500 10.30400  1.000 48.66552  ? 20  VAL A CG1  1 
ATOM   264  C CG2  . VAL A 1 20  ? -29.27000 -22.89100 8.59100   1.000 49.96744  ? 20  VAL A CG2  1 
ATOM   265  H H    . VAL A 1 20  ? -27.34700 -24.67900 9.39700   1.000 50.40819  ? 20  VAL A H    1 
ATOM   266  H HA   . VAL A 1 20  ? -26.72800 -22.17100 8.85800   1.000 48.25819  ? 20  VAL A HA   1 
ATOM   267  H HB   . VAL A 1 20  ? -28.77400 -23.15100 10.55400  1.000 46.17819  ? 20  VAL A HB   1 
ATOM   268  H HG11 . VAL A 1 20  ? -29.72800 -20.95800 10.23200  1.000 52.58819  ? 20  VAL A HG11 1 
ATOM   269  H HG12 . VAL A 1 20  ? -28.49100 -21.02200 11.22600  1.000 52.58819  ? 20  VAL A HG12 1 
ATOM   270  H HG13 . VAL A 1 20  ? -28.28800 -20.50900 9.73400   1.000 52.58819  ? 20  VAL A HG13 1 
ATOM   271  H HG21 . VAL A 1 20  ? -30.21100 -22.71000 8.74400   1.000 56.21819  ? 20  VAL A HG21 1 
ATOM   272  H HG22 . VAL A 1 20  ? -28.94200 -22.34500 7.85900   1.000 56.21819  ? 20  VAL A HG22 1 
ATOM   273  H HG23 . VAL A 1 20  ? -29.14300 -23.83100 8.38600   1.000 56.21819  ? 20  VAL A HG23 1 
ATOM   274  N N    . SER A 1 21  ? -26.00700 -23.23400 11.77300  1.000 41.57594  ? 21  SER A N    1 
ATOM   275  C CA   . SER A 1 21  ? -25.30800 -23.01300 13.02700  1.000 42.37043  ? 21  SER A CA   1 
ATOM   276  C C    . SER A 1 21  ? -24.48500 -24.25300 13.35200  1.000 43.25039  ? 21  SER A C    1 
ATOM   277  O O    . SER A 1 21  ? -24.56700 -25.26300 12.63800  1.000 50.95948  ? 21  SER A O    1 
ATOM   278  C CB   . SER A 1 21  ? -26.31300 -22.72000 14.14100  1.000 42.11486  ? 21  SER A CB   1 
ATOM   279  O OG   . SER A 1 21  ? -26.90600 -23.90800 14.64000  1.000 53.69460  ? 21  SER A OG   1 
ATOM   280  H H    . SER A 1 21  ? -26.32000 -24.03200 11.71100  1.000 49.29819  ? 21  SER A H    1 
ATOM   281  H HA   . SER A 1 21  ? -24.70900 -22.25500 12.94000  1.000 48.77819  ? 21  SER A HA   1 
ATOM   282  H HB2  . SER A 1 21  ? -25.86200 -22.26300 14.86600  1.000 47.62819  ? 21  SER A HB2  1 
ATOM   283  H HB3  . SER A 1 21  ? -27.01300 -22.15100 13.78400  1.000 47.62819  ? 21  SER A HB3  1 
ATOM   284  H HG   . SER A 1 21  ? -27.45300 -23.72200 15.25000  1.000 61.83819  ? 21  SER A HG   1 
ATOM   285  N N    . PRO A 1 22  ? -23.68400 -24.22700 14.41600  1.000 39.89145  ? 22  PRO A N    1 
ATOM   286  C CA   . PRO A 1 22  ? -23.06400 -25.47600 14.87600  1.000 38.55966  ? 22  PRO A CA   1 
ATOM   287  C C    . PRO A 1 22  ? -24.06400 -26.57800 15.15500  1.000 45.05218  ? 22  PRO A C    1 
ATOM   288  O O    . PRO A 1 22  ? -23.67300 -27.74900 15.13700  1.000 45.17803  ? 22  PRO A O    1 
ATOM   289  C CB   . PRO A 1 22  ? -22.33700 -25.06000 16.15800  1.000 45.62657  ? 22  PRO A CB   1 
ATOM   290  C CG   . PRO A 1 22  ? -22.08900 -23.57200 15.96600  1.000 44.76076  ? 22  PRO A CG   1 
ATOM   291  C CD   . PRO A 1 22  ? -23.28900 -23.06600 15.23100  1.000 42.86660  ? 22  PRO A CD   1 
ATOM   292  H HA   . PRO A 1 22  ? -22.41500 -25.78900 14.22700  1.000 49.24819  ? 22  PRO A HA   1 
ATOM   293  H HB2  . PRO A 1 22  ? -22.90600 -25.22000 16.92700  1.000 55.70819  ? 22  PRO A HB2  1 
ATOM   294  H HB3  . PRO A 1 22  ? -21.50000 -25.54400 16.23700  1.000 55.70819  ? 22  PRO A HB3  1 
ATOM   295  H HG2  . PRO A 1 22  ? -22.00900 -23.14000 16.83100  1.000 53.96819  ? 22  PRO A HG2  1 
ATOM   296  H HG3  . PRO A 1 22  ? -21.28400 -23.44000 15.44100  1.000 53.96819  ? 22  PRO A HG3  1 
ATOM   297  H HD2  . PRO A 1 22  ? -23.99100 -22.83300 15.85800  1.000 52.90819  ? 22  PRO A HD2  1 
ATOM   298  H HD3  . PRO A 1 22  ? -23.05000 -22.31600 14.66400  1.000 52.90819  ? 22  PRO A HD3  1 
ATOM   299  N N    . SER A 1 23  ? -25.33000 -26.26000 15.43800  1.000 53.64815  ? 23  SER A N    1 
ATOM   300  C CA   . SER A 1 23  ? -26.29800 -27.29200 15.77700  1.000 44.73445  ? 23  SER A CA   1 
ATOM   301  C C    . SER A 1 23  ? -27.47800 -27.38200 14.82800  1.000 41.41209  ? 23  SER A C    1 
ATOM   302  O O    . SER A 1 23  ? -28.29200 -28.29800 14.98100  1.000 42.48705  ? 23  SER A O    1 
ATOM   303  C CB   . SER A 1 23  ? -26.84100 -27.07300 17.19800  1.000 47.09289  ? 23  SER A CB   1 
ATOM   304  O OG   . SER A 1 23  ? -25.94500 -26.27300 17.94900  1.000 59.54528  ? 23  SER A OG   1 
ATOM   305  H H    . SER A 1 23  ? -25.64600 -25.46000 15.44000  1.000 65.04819  ? 23  SER A H    1 
ATOM   306  H HA   . SER A 1 23  ? -25.85600 -28.15500 15.76800  1.000 54.61819  ? 23  SER A HA   1 
ATOM   307  H HB2  . SER A 1 23  ? -27.69900 -26.62400 17.14400  1.000 55.84819  ? 23  SER A HB2  1 
ATOM   308  H HB3  . SER A 1 23  ? -26.94200 -27.93300 17.63500  1.000 55.84819  ? 23  SER A HB3  1 
ATOM   309  H HG   . SER A 1 23  ? -26.24500 -26.15600 18.72500  1.000 69.27819  ? 23  SER A HG   1 
ATOM   310  N N    . LEU A 1 24  ? -27.59200 -26.49500 13.84800  1.000 42.21887  ? 24  LEU A N    1 
ATOM   311  C CA   . LEU A 1 24  ? -28.81700 -26.37100 13.06600  1.000 33.63765  ? 24  LEU A CA   1 
ATOM   312  C C    . LEU A 1 24  ? -28.55000 -26.73400 11.61000  1.000 33.42530  ? 24  LEU A C    1 
ATOM   313  O O    . LEU A 1 24  ? -27.87600 -25.99100 10.88900  1.000 36.47126  ? 24  LEU A O    1 
ATOM   314  C CB   . LEU A 1 24  ? -29.38600 -24.96000 13.19500  1.000 35.48143  ? 24  LEU A CB   1 
ATOM   315  C CG   . LEU A 1 24  ? -30.77100 -24.79700 12.57600  1.000 35.05356  ? 24  LEU A CG   1 
ATOM   316  C CD1  . LEU A 1 24  ? -31.73300 -25.85100 13.12700  1.000 49.72517  ? 24  LEU A CD1  1 
ATOM   317  C CD2  . LEU A 1 24  ? -31.34400 -23.40400 12.78000  1.000 46.54099  ? 24  LEU A CD2  1 
ATOM   318  H H    . LEU A 1 24  ? -26.97100 -25.94900 13.61300  1.000 54.90819  ? 24  LEU A H    1 
ATOM   319  H HA   . LEU A 1 24  ? -29.46600 -27.00100 13.41100  1.000 45.57819  ? 24  LEU A HA   1 
ATOM   320  H HB2  . LEU A 1 24  ? -29.45300 -24.73500 14.13600  1.000 47.32819  ? 24  LEU A HB2  1 
ATOM   321  H HB3  . LEU A 1 24  ? -28.78700 -24.34000 12.75000  1.000 47.32819  ? 24  LEU A HB3  1 
ATOM   322  H HG   . LEU A 1 24  ? -30.69800 -24.94300 11.62000  1.000 47.50819  ? 24  LEU A HG   1 
ATOM   323  H HD11 . LEU A 1 24  ? -32.61400 -25.45500 13.20400  1.000 65.02819  ? 24  LEU A HD11 1 
ATOM   324  H HD12 . LEU A 1 24  ? -31.75800 -26.60800 12.52100  1.000 65.02819  ? 24  LEU A HD12 1 
ATOM   325  H HD13 . LEU A 1 24  ? -31.42700 -26.13200 14.00300  1.000 65.02819  ? 24  LEU A HD13 1 
ATOM   326  H HD21 . LEU A 1 24  ? -32.20300 -23.34700 12.33300  1.000 60.63819  ? 24  LEU A HD21 1 
ATOM   327  H HD22 . LEU A 1 24  ? -31.45400 -23.24400 13.73000  1.000 60.63819  ? 24  LEU A HD22 1 
ATOM   328  H HD23 . LEU A 1 24  ? -30.73200 -22.75300 12.40300  1.000 60.63819  ? 24  LEU A HD23 1 
ATOM   329  N N    . PHE A 1 25  ? -29.08000 -27.87700 11.18900  1.000 41.69853  ? 25  PHE A N    1 
ATOM   330  C CA   . PHE A 1 25  ? -28.99700 -28.36100 9.82000   1.000 33.39782  ? 25  PHE A CA   1 
ATOM   331  C C    . PHE A 1 25  ? -30.34500 -28.12000 9.16000   1.000 32.59418  ? 25  PHE A C    1 
ATOM   332  O O    . PHE A 1 25  ? -31.38500 -28.38900 9.76100   1.000 41.18528  ? 25  PHE A O    1 
ATOM   333  C CB   . PHE A 1 25  ? -28.64900 -29.85300 9.82100   1.000 39.70219  ? 25  PHE A CB   1 
ATOM   334  C CG   . PHE A 1 25  ? -28.08700 -30.36900 8.52400   1.000 31.94332  ? 25  PHE A CG   1 
ATOM   335  C CD1  . PHE A 1 25  ? -26.89000 -29.88800 8.03400   1.000 37.07719  ? 25  PHE A CD1  1 
ATOM   336  C CD2  . PHE A 1 25  ? -28.73200 -31.36800 7.82500   1.000 30.93048  ? 25  PHE A CD2  1 
ATOM   337  C CE1  . PHE A 1 25  ? -26.36900 -30.36600 6.85500   1.000 36.65332  ? 25  PHE A CE1  1 
ATOM   338  C CE2  . PHE A 1 25  ? -28.21000 -31.84700 6.65900   1.000 32.57203  ? 25  PHE A CE2  1 
ATOM   339  C CZ   . PHE A 1 25  ? -27.01900 -31.35100 6.18100   1.000 39.66508  ? 25  PHE A CZ   1 
ATOM   340  H H    . PHE A 1 25  ? -29.51200 -28.41200 11.70500  1.000 50.45819  ? 25  PHE A H    1 
ATOM   341  H HA   . PHE A 1 25  ? -28.31400 -27.87400 9.33400   1.000 41.40819  ? 25  PHE A HA   1 
ATOM   342  H HB2  . PHE A 1 25  ? -27.98900 -30.01600 10.51300  1.000 48.98819  ? 25  PHE A HB2  1 
ATOM   343  H HB3  . PHE A 1 25  ? -29.45400 -30.35800 10.01200  1.000 48.98819  ? 25  PHE A HB3  1 
ATOM   344  H HD1  . PHE A 1 25  ? -26.44100 -29.21800 8.49600   1.000 46.33819  ? 25  PHE A HD1  1 
ATOM   345  H HD2  . PHE A 1 25  ? -29.53500 -31.71100 8.14600   1.000 39.29819  ? 25  PHE A HD2  1 
ATOM   346  H HE1  . PHE A 1 25  ? -25.56400 -30.03100 6.53100   1.000 46.07819  ? 25  PHE A HE1  1 
ATOM   347  H HE2  . PHE A 1 25  ? -28.65600 -32.51500 6.19100   1.000 41.47819  ? 25  PHE A HE2  1 
ATOM   348  H HZ   . PHE A 1 25  ? -26.66900 -31.67500 5.38200   1.000 49.94819  ? 25  PHE A HZ   1 
ATOM   349  N N    . ILE A 1 26  ? -30.33900 -27.59900 7.93700   1.000 31.02613  ? 26  ILE A N    1 
ATOM   350  C CA   . ILE A 1 26  ? -31.57400 -27.44600 7.17700   1.000 31.69273  ? 26  ILE A CA   1 
ATOM   351  C C    . ILE A 1 26  ? -31.42400 -28.16300 5.84700   1.000 32.23676  ? 26  ILE A C    1 
ATOM   352  O O    . ILE A 1 26  ? -30.34300 -28.18400 5.25300   1.000 38.45100  ? 26  ILE A O    1 
ATOM   353  C CB   . ILE A 1 26  ? -31.94400 -25.96400 6.95600   1.000 35.40751  ? 26  ILE A CB   1 
ATOM   354  C CG1  . ILE A 1 26  ? -30.94600 -25.28500 6.01600   1.000 39.56599  ? 26  ILE A CG1  1 
ATOM   355  C CG2  . ILE A 1 26  ? -32.04900 -25.26500 8.31200   1.000 32.44700  ? 26  ILE A CG2  1 
ATOM   356  C CD1  . ILE A 1 26  ? -31.34600 -23.83600 5.70100   1.000 31.74138  ? 26  ILE A CD1  1 
ATOM   357  H H    . ILE A 1 26  ? -29.63400 -27.32700 7.52600   1.000 39.37819  ? 26  ILE A H    1 
ATOM   358  H HA   . ILE A 1 26  ? -32.30100 -27.86600 7.66100   1.000 40.50819  ? 26  ILE A HA   1 
ATOM   359  H HB   . ILE A 1 26  ? -32.81800 -25.93300 6.53600   1.000 44.83819  ? 26  ILE A HB   1 
ATOM   360  H HG12 . ILE A 1 26  ? -30.07100 -25.27300 6.43500   1.000 49.87819  ? 26  ILE A HG12 1 
ATOM   361  H HG13 . ILE A 1 26  ? -30.90700 -25.76100 5.17300   1.000 49.87819  ? 26  ILE A HG13 1 
ATOM   362  H HG21 . ILE A 1 26  ? -32.43000 -24.38200 8.18500   1.000 40.59819  ? 26  ILE A HG21 1 
ATOM   363  H HG22 . ILE A 1 26  ? -32.62000 -25.79100 8.89300   1.000 40.59819  ? 26  ILE A HG22 1 
ATOM   364  H HG23 . ILE A 1 26  ? -31.16300 -25.19100 8.69900   1.000 40.59819  ? 26  ILE A HG23 1 
ATOM   365  H HD11 . ILE A 1 26  ? -31.27100 -23.30400 6.50800   1.000 40.16819  ? 26  ILE A HD11 1 
ATOM   366  H HD12 . ILE A 1 26  ? -30.75100 -23.48700 5.01900   1.000 40.16819  ? 26  ILE A HD12 1 
ATOM   367  H HD13 . ILE A 1 26  ? -32.26100 -23.82400 5.37900   1.000 40.16819  ? 26  ILE A HD13 1 
ATOM   368  N N    . THR A 1 27  ? -32.52800 -28.72900 5.36600   1.000 26.49625  ? 27  THR A N    1 
ATOM   369  C CA   . THR A 1 27  ? -32.51400 -29.50000 4.13200   1.000 31.16062  ? 27  THR A CA   1 
ATOM   370  C C    . THR A 1 27  ? -33.92800 -29.54500 3.56300   1.000 35.23105  ? 27  THR A C    1 
ATOM   371  O O    . THR A 1 27  ? -34.84900 -28.91900 4.09800   1.000 34.85614  ? 27  THR A O    1 
ATOM   372  C CB   . THR A 1 27  ? -31.97700 -30.91200 4.37800   1.000 35.59479  ? 27  THR A CB   1 
ATOM   373  O OG1  . THR A 1 27  ? -32.01600 -31.65700 3.15500   1.000 33.56627  ? 27  THR A OG1  1 
ATOM   374  C CG2  . THR A 1 27  ? -32.81300 -31.64000 5.43000   1.000 29.90692  ? 27  THR A CG2  1 
ATOM   375  H H    . THR A 1 27  ? -33.30100 -28.68000 5.74000   1.000 37.09819  ? 27  THR A H    1 
ATOM   376  H HA   . THR A 1 27  ? -31.93800 -29.06200 3.48600   1.000 42.77819  ? 27  THR A HA   1 
ATOM   377  H HB   . THR A 1 27  ? -31.06200 -30.85900 4.69500   1.000 47.93819  ? 27  THR A HB   1 
ATOM   378  H HG1  . THR A 1 27  ? -31.54100 -31.28000 2.57400   1.000 45.32819  ? 27  THR A HG1  1 
ATOM   379  H HG21 . THR A 1 27  ? -32.43100 -32.51400 5.60800   1.000 40.80819  ? 27  THR A HG21 1 
ATOM   380  H HG22 . THR A 1 27  ? -32.82800 -31.13100 6.25500   1.000 40.80819  ? 27  THR A HG22 1 
ATOM   381  H HG23 . THR A 1 27  ? -33.72300 -31.75400 5.11400   1.000 40.80819  ? 27  THR A HG23 1 
ATOM   382  N N    . SER A 1 28  ? -34.10400 -30.32300 2.49300   1.000 40.09858  ? 28  SER A N    1 
ATOM   383  C CA   . SER A 1 28  ? -35.39800 -30.51300 1.85400   1.000 36.25441  ? 28  SER A CA   1 
ATOM   384  C C    . SER A 1 28  ? -36.01500 -31.82800 2.30500   1.000 40.22626  ? 28  SER A C    1 
ATOM   385  O O    . SER A 1 28  ? -35.33900 -32.85700 2.36400   1.000 48.59432  ? 28  SER A O    1 
ATOM   386  C CB   . SER A 1 28  ? -35.27000 -30.51000 0.33000   1.000 39.07778  ? 28  SER A CB   1 
ATOM   387  O OG   . SER A 1 28  ? -36.46900 -30.95100 -0.29500  1.000 46.77717  ? 28  SER A OG   1 
ATOM   388  H H    . SER A 1 28  ? -33.46900 -30.76100 2.11300   1.000 47.84819  ? 28  SER A H    1 
ATOM   389  H HA   . SER A 1 28  ? -35.99100 -29.79100 2.11100   1.000 42.87819  ? 28  SER A HA   1 
ATOM   390  H HB2  . SER A 1 28  ? -35.07500 -29.60700 0.03300   1.000 45.88819  ? 28  SER A HB2  1 
ATOM   391  H HB3  . SER A 1 28  ? -34.54700 -31.10400 0.07500   1.000 45.88819  ? 28  SER A HB3  1 
ATOM   392  H HG   . SER A 1 28  ? -36.37800 -30.94200 -1.13000  1.000 54.50819  ? 28  SER A HG   1 
ATOM   393  N N    . THR A 1 29  ? -37.31600 -31.79200 2.58800   1.000 30.89712  ? 29  THR A N    1 
ATOM   394  C CA   . THR A 1 29  ? -38.01300 -32.98300 3.06000   1.000 33.84296  ? 29  THR A CA   1 
ATOM   395  C C    . THR A 1 29  ? -37.87600 -34.14300 2.08000   1.000 37.46534  ? 29  THR A C    1 
ATOM   396  O O    . THR A 1 29  ? -37.75500 -35.29900 2.49700   1.000 34.21479  ? 29  THR A O    1 
ATOM   397  C CB   . THR A 1 29  ? -39.49800 -32.65300 3.28200   1.000 45.78875  ? 29  THR A CB   1 
ATOM   398  O OG1  . THR A 1 29  ? -39.64100 -31.59600 4.24300   1.000 36.68154  ? 29  THR A OG1  1 
ATOM   399  C CG2  . THR A 1 29  ? -40.27500 -33.86800 3.75300   1.000 56.26897  ? 29  THR A CG2  1 
ATOM   400  H H    . THR A 1 29  ? -37.81400 -31.09400 2.51500   1.000 46.96819  ? 29  THR A H    1 
ATOM   401  H HA   . THR A 1 29  ? -37.63400 -33.25800 3.90900   1.000 49.85819  ? 29  THR A HA   1 
ATOM   402  H HB   . THR A 1 29  ? -39.88300 -32.36400 2.44000   1.000 63.72819  ? 29  THR A HB   1 
ATOM   403  H HG1  . THR A 1 29  ? -40.45400 -31.42100 4.35900   1.000 53.14819  ? 29  THR A HG1  1 
ATOM   404  H HG21 . THR A 1 29  ? -41.09700 -33.58800 4.18600   1.000 75.40819  ? 29  THR A HG21 1 
ATOM   405  H HG22 . THR A 1 29  ? -40.49400 -34.43600 2.99800   1.000 75.40819  ? 29  THR A HG22 1 
ATOM   406  H HG23 . THR A 1 29  ? -39.74300 -34.37500 4.38500   1.000 75.40819  ? 29  THR A HG23 1 
ATOM   407  N N    . HIS A 1 30  ? -37.91300 -33.86700 0.77800   1.000 46.60568  ? 30  HIS A N    1 
ATOM   408  C CA   . HIS A 1 30  ? -37.82200 -34.94400 -0.20100  1.000 44.58778  ? 30  HIS A CA   1 
ATOM   409  C C    . HIS A 1 30  ? -36.47800 -35.65000 -0.18200  1.000 37.42593  ? 30  HIS A C    1 
ATOM   410  O O    . HIS A 1 30  ? -36.34400 -36.70000 -0.81500  1.000 46.14370  ? 30  HIS A O    1 
ATOM   411  C CB   . HIS A 1 30  ? -38.07500 -34.41000 -1.61600  1.000 56.66830  ? 30  HIS A CB   1 
ATOM   412  C CG   . HIS A 1 30  ? -39.49500 -34.55700 -2.06800  1.000 57.72078  ? 30  HIS A CG   1 
ATOM   413  N ND1  . HIS A 1 30  ? -39.84700 -35.16000 -3.25400  1.000 70.22888  ? 30  HIS A ND1  1 
ATOM   414  C CD2  . HIS A 1 30  ? -40.65400 -34.18400 -1.47700  1.000 66.67604  ? 30  HIS A CD2  1 
ATOM   415  C CE1  . HIS A 1 30  ? -41.16300 -35.14900 -3.37800  1.000 66.66812  ? 30  HIS A CE1  1 
ATOM   416  N NE2  . HIS A 1 30  ? -41.67600 -34.56300 -2.31200  1.000 70.66520  ? 30  HIS A NE2  1 
ATOM   417  H H    . HIS A 1 30  ? -37.98900 -33.07900 0.44200   1.000 58.69819  ? 30  HIS A H    1 
ATOM   418  H HA   . HIS A 1 30  ? -38.50600 -35.60300 -0.00500  1.000 55.38819  ? 30  HIS A HA   1 
ATOM   419  H HB2  . HIS A 1 30  ? -37.85100 -33.46600 -1.64100  1.000 69.39819  ? 30  HIS A HB2  1 
ATOM   420  H HB3  . HIS A 1 30  ? -37.51300 -34.89700 -2.23900  1.000 69.39819  ? 30  HIS A HB3  1 
ATOM   421  H HD2  . HIS A 1 30  ? -40.74000 -33.75300 -0.65800  1.000 80.37819  ? 30  HIS A HD2  1 
ATOM   422  H HE1  . HIS A 1 30  ? -41.64500 -35.49500 -4.09400  1.000 78.31819  ? 30  HIS A HE1  1 
ATOM   423  H HE2  . HIS A 1 30  ? -42.51400 -34.43700 -2.16500  1.000 83.87819  ? 30  HIS A HE2  1 
ATOM   424  N N    . VAL A 1 31  ? -35.48200 -35.08700 0.49600   1.000 45.64456  ? 31  VAL A N    1 
ATOM   425  C CA   . VAL A 1 31  ? -34.11200 -35.58700 0.44200   1.000 40.59252  ? 31  VAL A CA   1 
ATOM   426  C C    . VAL A 1 31  ? -33.72700 -36.42900 1.65900   1.000 43.37696  ? 31  VAL A C    1 
ATOM   427  O O    . VAL A 1 31  ? -32.77100 -37.21500 1.57700   1.000 47.03888  ? 31  VAL A O    1 
ATOM   428  C CB   . VAL A 1 31  ? -33.14300 -34.39300 0.28400   1.000 40.49529  ? 31  VAL A CB   1 
ATOM   429  C CG1  . VAL A 1 31  ? -31.71900 -34.78500 0.59300   1.000 49.29851  ? 31  VAL A CG1  1 
ATOM   430  C CG2  . VAL A 1 31  ? -33.25400 -33.82700 -1.12500  1.000 41.39928  ? 31  VAL A CG2  1 
ATOM   431  H H    . VAL A 1 31  ? -35.57400 -34.39900 1.00400   1.000 53.23819  ? 31  VAL A H    1 
ATOM   432  H HA   . VAL A 1 31  ? -34.01600 -36.14800 -0.34400  1.000 47.21819  ? 31  VAL A HA   1 
ATOM   433  H HB   . VAL A 1 31  ? -33.40100 -33.69500 0.90600   1.000 47.83819  ? 31  VAL A HB   1 
ATOM   434  H HG11 . VAL A 1 31  ? -31.54500 -35.66500 0.22600   1.000 58.48819  ? 31  VAL A HG11 1 
ATOM   435  H HG12 . VAL A 1 31  ? -31.12400 -34.13200 0.19800   1.000 58.48819  ? 31  VAL A HG12 1 
ATOM   436  H HG13 . VAL A 1 31  ? -31.59500 -34.79300 1.55500   1.000 58.48819  ? 31  VAL A HG13 1 
ATOM   437  H HG21 . VAL A 1 31  ? -32.68400 -33.04600 -1.19700  1.000 48.55819  ? 31  VAL A HG21 1 
ATOM   438  H HG22 . VAL A 1 31  ? -32.97100 -34.50300 -1.76000  1.000 48.55819  ? 31  VAL A HG22 1 
ATOM   439  H HG23 . VAL A 1 31  ? -34.17700 -33.57900 -1.29400  1.000 48.55819  ? 31  VAL A HG23 1 
ATOM   440  N N    . ILE A 1 32  ? -34.45000 -36.30500 2.77000   1.000 41.41770  ? 32  ILE A N    1 
ATOM   441  C CA   . ILE A 1 32  ? -33.99500 -36.91500 4.02600   1.000 36.17358  ? 32  ILE A CA   1 
ATOM   442  C C    . ILE A 1 32  ? -34.08800 -38.43200 3.90400   1.000 42.58445  ? 32  ILE A C    1 
ATOM   443  O O    . ILE A 1 32  ? -35.10500 -38.94500 3.39800   1.000 42.84720  ? 32  ILE A O    1 
ATOM   444  C CB   . ILE A 1 32  ? -34.83200 -36.39200 5.22000   1.000 42.80294  ? 32  ILE A CB   1 
ATOM   445  C CG1  . ILE A 1 32  ? -34.53700 -34.89800 5.42200   1.000 49.32137  ? 32  ILE A CG1  1 
ATOM   446  C CG2  . ILE A 1 32  ? -34.56300 -37.25800 6.44500   1.000 46.89896  ? 32  ILE A CG2  1 
ATOM   447  C CD1  . ILE A 1 32  ? -34.99200 -34.26900 6.71600   1.000 70.12795  ? 32  ILE A CD1  1 
ATOM   448  H H    . ILE A 1 32  ? -35.19600 -35.88100 2.82800   1.000 52.52819  ? 32  ILE A H    1 
ATOM   449  H HA   . ILE A 1 32  ? -33.07600 -36.65300 4.17400   1.000 46.09819  ? 32  ILE A HA   1 
ATOM   450  H HB   . ILE A 1 32  ? -35.77000 -36.48300 4.99100   1.000 54.14819  ? 32  ILE A HB   1 
ATOM   451  H HG12 . ILE A 1 32  ? -33.57800 -34.77000 5.36600   1.000 62.80819  ? 32  ILE A HG12 1 
ATOM   452  H HG13 . ILE A 1 32  ? -34.96500 -34.40800 4.70300   1.000 62.80819  ? 32  ILE A HG13 1 
ATOM   453  H HG21 . ILE A 1 32  ? -34.94500 -36.83600 7.22900   1.000 58.44819  ? 32  ILE A HG21 1 
ATOM   454  H HG22 . ILE A 1 32  ? -34.97300 -38.12800 6.32000   1.000 58.44819  ? 32  ILE A HG22 1 
ATOM   455  H HG23 . ILE A 1 32  ? -33.60500 -37.35500 6.55800   1.000 58.44819  ? 32  ILE A HG23 1 
ATOM   456  H HD11 . ILE A 1 32  ? -34.78600 -33.32200 6.68600   1.000 87.72819  ? 32  ILE A HD11 1 
ATOM   457  H HD12 . ILE A 1 32  ? -35.94800 -34.40000 6.81400   1.000 87.72819  ? 32  ILE A HD12 1 
ATOM   458  H HD13 . ILE A 1 32  ? -34.52100 -34.68300 7.45600   1.000 87.72819  ? 32  ILE A HD13 1 
ATOM   459  N N    . PRO A 1 33  ? -33.06200 -39.19600 4.29300   1.000 39.99340  ? 33  PRO A N    1 
ATOM   460  C CA   . PRO A 1 33  ? -33.17200 -40.66800 4.25300   1.000 36.41996  ? 33  PRO A CA   1 
ATOM   461  C C    . PRO A 1 33  ? -34.13900 -41.16400 5.32300   1.000 40.00791  ? 33  PRO A C    1 
ATOM   462  O O    . PRO A 1 33  ? -33.98700 -40.84600 6.50400   1.000 52.10379  ? 33  PRO A O    1 
ATOM   463  C CB   . PRO A 1 33  ? -31.73300 -41.14400 4.51300   1.000 40.73792  ? 33  PRO A CB   1 
ATOM   464  C CG   . PRO A 1 33  ? -30.84200 -39.88900 4.40700   1.000 37.57597  ? 33  PRO A CG   1 
ATOM   465  C CD   . PRO A 1 33  ? -31.74700 -38.75300 4.79300   1.000 33.59600  ? 33  PRO A CD   1 
ATOM   466  H HA   . PRO A 1 33  ? -33.46500 -40.96800 3.37800   1.000 45.47819  ? 33  PRO A HA   1 
ATOM   467  H HB2  . PRO A 1 33  ? -31.67400 -41.52900 5.40200   1.000 50.55819  ? 33  PRO A HB2  1 
ATOM   468  H HB3  . PRO A 1 33  ? -31.48100 -41.79700 3.84200   1.000 50.55819  ? 33  PRO A HB3  1 
ATOM   469  H HG2  . PRO A 1 33  ? -30.09700 -39.96200 5.02400   1.000 47.92819  ? 33  PRO A HG2  1 
ATOM   470  H HG3  . PRO A 1 33  ? -30.52800 -39.78600 3.49600   1.000 47.92819  ? 33  PRO A HG3  1 
ATOM   471  H HD2  . PRO A 1 33  ? -31.76700 -38.64600 5.75700   1.000 43.87819  ? 33  PRO A HD2  1 
ATOM   472  H HD3  . PRO A 1 33  ? -31.45600 -37.94300 4.34800   1.000 43.87819  ? 33  PRO A HD3  1 
ATOM   473  N N    . GLN A 1 34  ? -35.13500 -41.95700 4.91400   1.000 44.26295  ? 34  GLN A N    1 
ATOM   474  C CA   . GLN A 1 34  ? -36.22400 -42.35600 5.80600   1.000 44.52791  ? 34  GLN A CA   1 
ATOM   475  C C    . GLN A 1 34  ? -35.97100 -43.68700 6.50200   1.000 46.74361  ? 34  GLN A C    1 
ATOM   476  O O    . GLN A 1 34  ? -36.77600 -44.10300 7.34800   1.000 51.97087  ? 34  GLN A O    1 
ATOM   477  C CB   . GLN A 1 34  ? -37.53500 -42.43700 5.02100   1.000 45.61347  ? 34  GLN A CB   1 
ATOM   478  C CG   . GLN A 1 34  ? -37.98700 -41.13200 4.42600   1.000 44.54128  ? 34  GLN A CG   1 
ATOM   479  C CD   . GLN A 1 34  ? -38.50700 -40.17400 5.47900   1.000 59.57139  ? 34  GLN A CD   1 
ATOM   480  O OE1  . GLN A 1 34  ? -39.63600 -40.30300 5.95400   1.000 58.29528  ? 34  GLN A OE1  1 
ATOM   481  N NE2  . GLN A 1 34  ? -37.67100 -39.23100 5.87700   1.000 55.87167  ? 34  GLN A NE2  1 
ATOM   482  H H    . GLN A 1 34  ? -35.20100 -42.27800 4.11900   1.000 51.96819  ? 34  GLN A H    1 
ATOM   483  H HA   . GLN A 1 34  ? -36.33000 -41.67900 6.49200   1.000 51.42819  ? 34  GLN A HA   1 
ATOM   484  H HB2  . GLN A 1 34  ? -37.42200 -43.06900 4.29400   1.000 52.06819  ? 34  GLN A HB2  1 
ATOM   485  H HB3  . GLN A 1 34  ? -38.23500 -42.74700 5.61700   1.000 52.06819  ? 34  GLN A HB3  1 
ATOM   486  H HG2  . GLN A 1 34  ? -37.23800 -40.71000 3.97700   1.000 51.85819  ? 34  GLN A HG2  1 
ATOM   487  H HG3  . GLN A 1 34  ? -38.70300 -41.30200 3.79400   1.000 51.85819  ? 34  GLN A HG3  1 
ATOM   488  H HE21 . GLN A 1 34  ? -36.88700 -39.17500 5.52700   1.000 67.24819  ? 34  GLN A HE21 1 
ATOM   489  H HE22 . GLN A 1 34  ? -37.91600 -38.66400 6.47500   1.000 67.24819  ? 34  GLN A HE22 1 
ATOM   490  N N    . GLY A 1 35  ? -34.88400 -44.36400 6.15400   1.000 48.47545  ? 35  GLY A N    1 
ATOM   491  C CA   . GLY A 1 35  ? -34.54500 -45.63900 6.74500   1.000 53.69253  ? 35  GLY A CA   1 
ATOM   492  C C    . GLY A 1 35  ? -33.35800 -45.55200 7.67800   1.000 51.38828  ? 35  GLY A C    1 
ATOM   493  O O    . GLY A 1 35  ? -32.85800 -46.57800 8.14000   1.000 54.44006  ? 35  GLY A O    1 
ATOM   494  H H    . GLY A 1 35  ? -34.31800 -44.09700 5.56500   1.000 58.02819  ? 35  GLY A H    1 
ATOM   495  H HA2  . GLY A 1 35  ? -35.30300 -45.98000 7.24500   1.000 62.86819  ? 35  GLY A HA2  1 
ATOM   496  H HA3  . GLY A 1 35  ? -34.33400 -46.27200 6.04100   1.000 62.86819  ? 35  GLY A HA3  1 
ATOM   497  N N    . THR A 1 36  ? -32.91600 -44.33800 7.98700   1.000 58.67781  ? 36  THR A N    1 
ATOM   498  C CA   . THR A 1 36  ? -31.71900 -44.09800 8.78000   1.000 57.30869  ? 36  THR A CA   1 
ATOM   499  C C    . THR A 1 36  ? -32.10600 -43.69200 10.19200  1.000 53.81896  ? 36  THR A C    1 
ATOM   500  O O    . THR A 1 36  ? -33.10500 -42.99400 10.39300  1.000 54.58147  ? 36  THR A O    1 
ATOM   501  C CB   . THR A 1 36  ? -30.87000 -43.00200 8.13000   1.000 57.12750  ? 36  THR A CB   1 
ATOM   502  O OG1  . THR A 1 36  ? -30.36800 -43.47500 6.87300   1.000 63.28523  ? 36  THR A OG1  1 
ATOM   503  C CG2  . THR A 1 36  ? -29.71200 -42.59000 9.00200   1.000 76.94203  ? 36  THR A CG2  1 
ATOM   504  H H    . THR A 1 36  ? -33.30700 -43.61300 7.74200   1.000 63.73819  ? 36  THR A H    1 
ATOM   505  H HA   . THR A 1 36  ? -31.19000 -44.91000 8.82600   1.000 62.40819  ? 36  THR A HA   1 
ATOM   506  H HB   . THR A 1 36  ? -31.42400 -42.22100 7.97600   1.000 63.63819  ? 36  THR A HB   1 
ATOM   507  H HG1  . THR A 1 36  ? -29.90000 -42.88000 6.50800   1.000 70.91819  ? 36  THR A HG1  1 
ATOM   508  H HG21 . THR A 1 36  ? -30.02700 -42.03300 9.73100   1.000 87.64819  ? 36  THR A HG21 1 
ATOM   509  H HG22 . THR A 1 36  ? -29.27700 -43.37500 9.37000   1.000 87.64819  ? 36  THR A HG22 1 
ATOM   510  H HG23 . THR A 1 36  ? -29.06800 -42.08700 8.48000   1.000 87.64819  ? 36  THR A HG23 1 
ATOM   511  N N    . GLN A 1 37  ? -31.30800 -44.13500 11.16600  1.000 48.80561  ? 37  GLN A N    1 
ATOM   512  C CA   . GLN A 1 37  ? -31.59400 -43.91600 12.57400  1.000 50.76055  ? 37  GLN A CA   1 
ATOM   513  C C    . GLN A 1 37  ? -30.51900 -43.09000 13.26700  1.000 45.98118  ? 37  GLN A C    1 
ATOM   514  O O    . GLN A 1 37  ? -30.60500 -42.88000 14.48300  1.000 49.08135  ? 37  GLN A O    1 
ATOM   515  C CB   . GLN A 1 37  ? -31.76900 -45.26700 13.28300  1.000 45.93550  ? 37  GLN A CB   1 
ATOM   516  C CG   . GLN A 1 37  ? -32.55500 -46.29600 12.47000  1.000 51.34808  ? 37  GLN A CG   1 
ATOM   517  C CD   . GLN A 1 37  ? -32.91800 -47.53300 13.27900  1.000 57.19989  ? 37  GLN A CD   1 
ATOM   518  O OE1  . GLN A 1 37  ? -32.34300 -47.78600 14.33800  1.000 67.36723  ? 37  GLN A OE1  1 
ATOM   519  N NE2  . GLN A 1 37  ? -33.88500 -48.30300 12.78700  1.000 70.75965  ? 37  GLN A NE2  1 
ATOM   520  H H    . GLN A 1 37  ? -30.58100 -44.57400 11.02700  1.000 58.50819  ? 37  GLN A H    1 
ATOM   521  H HA   . GLN A 1 37  ? -32.43100 -43.43300 12.65300  1.000 60.14819  ? 37  GLN A HA   1 
ATOM   522  H HB2  . GLN A 1 37  ? -30.89200 -45.64000 13.46500  1.000 52.39819  ? 37  GLN A HB2  1 
ATOM   523  H HB3  . GLN A 1 37  ? -32.24400 -45.12300 14.11700  1.000 52.39819  ? 37  GLN A HB3  1 
ATOM   524  H HG2  . GLN A 1 37  ? -33.37800 -45.89000 12.15700  1.000 58.09819  ? 37  GLN A HG2  1 
ATOM   525  H HG3  . GLN A 1 37  ? -32.01700 -46.58100 11.71500  1.000 58.09819  ? 37  GLN A HG3  1 
ATOM   526  H HE21 . GLN A 1 37  ? -34.26600 -48.09400 12.04500  1.000 78.22819  ? 37  GLN A HE21 1 
ATOM   527  H HE22 . GLN A 1 37  ? -34.12600 -49.01300 13.20900  1.000 78.22819  ? 37  GLN A HE22 1 
ATOM   528  N N    . GLU A 1 38  ? -29.53000 -42.59500 12.52600  1.000 46.55859  ? 38  GLU A N    1 
ATOM   529  C CA   . GLU A 1 38  ? -28.55100 -41.66100 13.05900  1.000 51.36835  ? 38  GLU A CA   1 
ATOM   530  C C    . GLU A 1 38  ? -28.15000 -40.69700 11.95500  1.000 47.85047  ? 38  GLU A C    1 
ATOM   531  O O    . GLU A 1 38  ? -28.01900 -41.09300 10.79500  1.000 43.08408  ? 38  GLU A O    1 
ATOM   532  C CB   . GLU A 1 38  ? -27.31000 -42.37900 13.59800  1.000 53.61595  ? 38  GLU A CB   1 
ATOM   533  C CG   . GLU A 1 38  ? -26.59300 -43.27000 12.59000  1.000 53.84191  ? 38  GLU A CG   1 
ATOM   534  C CD   . GLU A 1 38  ? -25.10400 -43.31000 12.84900  1.000 74.88878  ? 38  GLU A CD   1 
ATOM   535  O OE1  . GLU A 1 38  ? -24.47100 -42.24200 12.69000  1.000 73.06740  ? 38  GLU A OE1  1 
ATOM   536  O OE2  . GLU A 1 38  ? -24.57800 -44.38200 13.23100  1.000 84.12440  ? 38  GLU A OE2  1 
ATOM   537  H H    . GLU A 1 38  ? -29.40400 -42.79000 11.69800  1.000 53.61819  ? 38  GLU A H    1 
ATOM   538  H HA   . GLU A 1 38  ? -28.95100 -41.15200 13.78100  1.000 59.82819  ? 38  GLU A HA   1 
ATOM   539  H HB2  . GLU A 1 38  ? -26.67500 -41.71200 13.90200  1.000 61.50819  ? 38  GLU A HB2  1 
ATOM   540  H HB3  . GLU A 1 38  ? -27.57700 -42.93800 14.34500  1.000 61.50819  ? 38  GLU A HB3  1 
ATOM   541  H HG2  . GLU A 1 38  ? -26.93700 -44.17400 12.66400  1.000 61.72819  ? 38  GLU A HG2  1 
ATOM   542  H HG3  . GLU A 1 38  ? -26.73400 -42.93200 11.69300  1.000 61.72819  ? 38  GLU A HG3  1 
ATOM   543  N N    . PHE A 1 39  ? -27.95200 -39.43500 12.31900  1.000 49.51130  ? 39  PHE A N    1 
ATOM   544  C CA   . PHE A 1 39  ? -27.51400 -38.41400 11.37800  1.000 41.61540  ? 39  PHE A CA   1 
ATOM   545  C C    . PHE A 1 39  ? -26.25900 -37.78900 11.95000  1.000 41.61465  ? 39  PHE A C    1 
ATOM   546  O O    . PHE A 1 39  ? -26.26700 -37.30800 13.09000  1.000 47.10505  ? 39  PHE A O    1 
ATOM   547  C CB   . PHE A 1 39  ? -28.58600 -37.35400 11.14200  1.000 43.89722  ? 39  PHE A CB   1 
ATOM   548  C CG   . PHE A 1 39  ? -29.74300 -37.82300 10.31000  1.000 44.41500  ? 39  PHE A CG   1 
ATOM   549  C CD1  . PHE A 1 39  ? -29.55300 -38.56600 9.14900   1.000 38.27924  ? 39  PHE A CD1  1 
ATOM   550  C CD2  . PHE A 1 39  ? -31.03300 -37.50200 10.70000  1.000 36.13858  ? 39  PHE A CD2  1 
ATOM   551  C CE1  . PHE A 1 39  ? -30.64900 -38.98300 8.39600   1.000 43.43165  ? 39  PHE A CE1  1 
ATOM   552  C CE2  . PHE A 1 39  ? -32.12400 -37.90200 9.96800   1.000 41.25919  ? 39  PHE A CE2  1 
ATOM   553  C CZ   . PHE A 1 39  ? -31.94500 -38.64500 8.81400   1.000 43.41476  ? 39  PHE A CZ   1 
ATOM   554  H H    . PHE A 1 39  ? -28.06700 -39.14100 13.11900  1.000 60.03819  ? 39  PHE A H    1 
ATOM   555  H HA   . PHE A 1 39  ? -27.28500 -38.82500 10.53100  1.000 51.76819  ? 39  PHE A HA   1 
ATOM   556  H HB2  . PHE A 1 39  ? -28.93600 -37.06900 12.00000  1.000 55.28819  ? 39  PHE A HB2  1 
ATOM   557  H HB3  . PHE A 1 39  ? -28.18200 -36.59900 10.68600  1.000 55.28819  ? 39  PHE A HB3  1 
ATOM   558  H HD1  . PHE A 1 39  ? -28.69200 -38.78700 8.87600   1.000 48.89819  ? 39  PHE A HD1  1 
ATOM   559  H HD2  . PHE A 1 39  ? -31.16300 -37.00300 11.47400  1.000 46.12819  ? 39  PHE A HD2  1 
ATOM   560  H HE1  . PHE A 1 39  ? -30.52200 -39.48100 7.62100   1.000 55.05819  ? 39  PHE A HE1  1 
ATOM   561  H HE2  . PHE A 1 39  ? -32.98200 -37.67700 10.24900  1.000 52.29819  ? 39  PHE A HE2  1 
ATOM   562  H HZ   . PHE A 1 39  ? -32.68200 -38.91900 8.31700   1.000 54.94819  ? 39  PHE A HZ   1 
ATOM   563  N N    . PHE A 1 40  ? -25.18200 -37.82000 11.16800  1.000 51.44233  ? 40  PHE A N    1 
ATOM   564  C CA   . PHE A 1 40  ? -23.88000 -37.29700 11.58100  1.000 53.26013  ? 40  PHE A CA   1 
ATOM   565  C C    . PHE A 1 40  ? -23.46200 -37.88300 12.92500  1.000 56.79470  ? 40  PHE A C    1 
ATOM   566  O O    . PHE A 1 40  ? -22.94400 -37.18500 13.80200  1.000 48.42765  ? 40  PHE A O    1 
ATOM   567  C CB   . PHE A 1 40  ? -23.88800 -35.77200 11.63700  1.000 43.37509  ? 40  PHE A CB   1 
ATOM   568  C CG   . PHE A 1 40  ? -24.29500 -35.12500 10.35200  1.000 41.80905  ? 40  PHE A CG   1 
ATOM   569  C CD1  . PHE A 1 40  ? -23.46600 -35.18000 9.25300   1.000 42.22230  ? 40  PHE A CD1  1 
ATOM   570  C CD2  . PHE A 1 40  ? -25.50300 -34.46400 10.23900  1.000 39.08807  ? 40  PHE A CD2  1 
ATOM   571  C CE1  . PHE A 1 40  ? -23.82900 -34.58700 8.06400   1.000 37.52336  ? 40  PHE A CE1  1 
ATOM   572  C CE2  . PHE A 1 40  ? -25.86400 -33.87000 9.06000   1.000 38.65079  ? 40  PHE A CE2  1 
ATOM   573  C CZ   . PHE A 1 40  ? -25.02300 -33.93000 7.96700   1.000 37.01205  ? 40  PHE A CZ   1 
ATOM   574  H H    . PHE A 1 40  ? -25.18000 -38.14800 10.37300  1.000 59.67819  ? 40  PHE A H    1 
ATOM   575  H HA   . PHE A 1 40  ? -23.21700 -37.56400 10.92500  1.000 61.50819  ? 40  PHE A HA   1 
ATOM   576  H HB2  . PHE A 1 40  ? -24.51200 -35.48800 12.32300  1.000 50.18819  ? 40  PHE A HB2  1 
ATOM   577  H HB3  . PHE A 1 40  ? -22.99500 -35.46200 11.85600  1.000 50.18819  ? 40  PHE A HB3  1 
ATOM   578  H HD1  . PHE A 1 40  ? -22.65000 -35.62300 9.31500   1.000 50.19819  ? 40  PHE A HD1  1 
ATOM   579  H HD2  . PHE A 1 40  ? -26.07300 -34.41600 10.97300  1.000 46.75819  ? 40  PHE A HD2  1 
ATOM   580  H HE1  . PHE A 1 40  ? -23.26000 -34.62900 7.33000   1.000 45.34819  ? 40  PHE A HE1  1 
ATOM   581  H HE2  . PHE A 1 40  ? -26.67900 -33.42700 8.99400   1.000 47.07819  ? 40  PHE A HE2  1 
ATOM   582  H HZ   . PHE A 1 40  ? -25.27200 -33.53000 7.16500   1.000 45.29819  ? 40  PHE A HZ   1 
ATOM   583  N N    . GLY A 1 41  ? -23.69100 -39.18400 13.08300  1.000 52.31707  ? 41  GLY A N    1 
ATOM   584  C CA   . GLY A 1 41  ? -23.32300 -39.87800 14.29400  1.000 47.11052  ? 41  GLY A CA   1 
ATOM   585  C C    . GLY A 1 41  ? -24.24000 -39.65200 15.46900  1.000 46.28718  ? 41  GLY A C    1 
ATOM   586  O O    . GLY A 1 41  ? -24.04600 -40.28500 16.51000  1.000 48.58780  ? 41  GLY A O    1 
ATOM   587  H H    . GLY A 1 41  ? -24.06300 -39.68600 12.49200  1.000 63.46819  ? 41  GLY A H    1 
ATOM   588  H HA2  . GLY A 1 41  ? -23.28900 -40.83000 14.11900  1.000 55.71819  ? 41  GLY A HA2  1 
ATOM   589  H HA3  . GLY A 1 41  ? -22.43300 -39.59400 14.55600  1.000 55.71819  ? 41  GLY A HA3  1 
ATOM   590  N N    . VAL A 1 42  ? -25.23200 -38.77900 15.34800  1.000 56.65819  ? 42  VAL A N    1 
ATOM   591  C CA   . VAL A 1 42  ? -26.16500 -38.54500 16.44400  1.000 47.37691  ? 42  VAL A CA   1 
ATOM   592  C C    . VAL A 1 42  ? -27.41300 -39.38200 16.18500  1.000 53.07195  ? 42  VAL A C    1 
ATOM   593  O O    . VAL A 1 42  ? -27.95200 -39.33600 15.07100  1.000 51.86960  ? 42  VAL A O    1 
ATOM   594  C CB   . VAL A 1 42  ? -26.52500 -37.05800 16.56600  1.000 45.63862  ? 42  VAL A CB   1 
ATOM   595  C CG1  . VAL A 1 42  ? -27.40000 -36.82300 17.77800  1.000 44.89267  ? 42  VAL A CG1  1 
ATOM   596  C CG2  . VAL A 1 42  ? -25.27400 -36.20300 16.63500  1.000 51.39707  ? 42  VAL A CG2  1 
ATOM   597  H H    . VAL A 1 42  ? -25.38800 -38.31000 14.64400  1.000 65.62819  ? 42  VAL A H    1 
ATOM   598  H HA   . VAL A 1 42  ? -25.75300 -38.81900 17.27600  1.000 53.63819  ? 42  VAL A HA   1 
ATOM   599  H HB   . VAL A 1 42  ? -27.02600 -36.79000 15.78000  1.000 52.15819  ? 42  VAL A HB   1 
ATOM   600  H HG11 . VAL A 1 42  ? -27.53100 -35.86900 17.89100  1.000 50.06819  ? 42  VAL A HG11 1 
ATOM   601  H HG12 . VAL A 1 42  ? -28.25600 -37.25900 17.64200  1.000 50.06819  ? 42  VAL A HG12 1 
ATOM   602  H HG13 . VAL A 1 42  ? -26.96000 -37.19100 18.56000  1.000 50.06819  ? 42  VAL A HG13 1 
ATOM   603  H HG21 . VAL A 1 42  ? -25.52100 -35.31100 16.92200  1.000 59.06819  ? 42  VAL A HG21 1 
ATOM   604  H HG22 . VAL A 1 42  ? -24.65800 -36.59700 17.27300  1.000 59.06819  ? 42  VAL A HG22 1 
ATOM   605  H HG23 . VAL A 1 42  ? -24.86400 -36.17000 15.75700  1.000 59.06819  ? 42  VAL A HG23 1 
ATOM   606  N N    . PRO A 1 43  ? -27.91800 -40.14300 17.15300  1.000 54.91483  ? 43  PRO A N    1 
ATOM   607  C CA   . PRO A 1 43  ? -29.14600 -40.91300 16.89500  1.000 58.22905  ? 43  PRO A CA   1 
ATOM   608  C C    . PRO A 1 43  ? -30.32900 -39.98300 16.65000  1.000 51.48124  ? 43  PRO A C    1 
ATOM   609  O O    . PRO A 1 43  ? -30.45900 -38.93900 17.29200  1.000 49.14744  ? 43  PRO A O    1 
ATOM   610  C CB   . PRO A 1 43  ? -29.33000 -41.74600 18.17000  1.000 57.82133  ? 43  PRO A CB   1 
ATOM   611  C CG   . PRO A 1 43  ? -28.00500 -41.70300 18.86800  1.000 53.72794  ? 43  PRO A CG   1 
ATOM   612  C CD   . PRO A 1 43  ? -27.35000 -40.41400 18.48600  1.000 53.63651  ? 43  PRO A CD   1 
ATOM   613  H HA   . PRO A 1 43  ? -29.02800 -41.50200 16.13300  1.000 66.43819  ? 43  PRO A HA   1 
ATOM   614  H HB2  . PRO A 1 43  ? -30.02100 -41.34800 18.72300  1.000 63.83819  ? 43  PRO A HB2  1 
ATOM   615  H HB3  . PRO A 1 43  ? -29.56300 -42.65700 17.93300  1.000 63.83819  ? 43  PRO A HB3  1 
ATOM   616  H HG2  . PRO A 1 43  ? -28.14600 -41.73900 19.82700  1.000 58.09819  ? 43  PRO A HG2  1 
ATOM   617  H HG3  . PRO A 1 43  ? -27.46500 -42.45500 18.57800  1.000 58.09819  ? 43  PRO A HG3  1 
ATOM   618  H HD2  . PRO A 1 43  ? -27.59200 -39.71100 19.10900  1.000 59.33819  ? 43  PRO A HD2  1 
ATOM   619  H HD3  . PRO A 1 43  ? -26.38900 -40.53200 18.43300  1.000 59.33819  ? 43  PRO A HD3  1 
ATOM   620  N N    . THR A 1 44  ? -31.19300 -40.37000 15.70100  1.000 55.61615  ? 44  THR A N    1 
ATOM   621  C CA   . THR A 1 44  ? -32.32900 -39.52000 15.33800  1.000 52.36815  ? 44  THR A CA   1 
ATOM   622  C C    . THR A 1 44  ? -33.25200 -39.28500 16.52800  1.000 50.37094  ? 44  THR A C    1 
ATOM   623  O O    . THR A 1 44  ? -33.87600 -38.22100 16.63100  1.000 49.00782  ? 44  THR A O    1 
ATOM   624  C CB   . THR A 1 44  ? -33.12000 -40.14100 14.18000  1.000 49.22521  ? 44  THR A CB   1 
ATOM   625  O OG1  . THR A 1 44  ? -33.42800 -41.50700 14.49000  1.000 50.70310  ? 44  THR A OG1  1 
ATOM   626  C CG2  . THR A 1 44  ? -32.33500 -40.06900 12.86500  1.000 43.21792  ? 44  THR A CG2  1 
ATOM   627  H H    . THR A 1 44  ? -31.14300 -41.10700 15.26100  1.000 66.42819  ? 44  THR A H    1 
ATOM   628  H HA   . THR A 1 44  ? -31.99700 -38.65800 15.04500  1.000 63.29819  ? 44  THR A HA   1 
ATOM   629  H HB   . THR A 1 44  ? -33.94800 -39.64900 14.06300  1.000 60.00819  ? 44  THR A HB   1 
ATOM   630  H HG1  . THR A 1 44  ? -33.70000 -41.90300 13.80100  1.000 60.34819  ? 44  THR A HG1  1 
ATOM   631  H HG21 . THR A 1 44  ? -32.82700 -40.51900 12.16000  1.000 54.07819  ? 44  THR A HG21 1 
ATOM   632  H HG22 . THR A 1 44  ? -32.19900 -39.14300 12.61300  1.000 54.07819  ? 44  THR A HG22 1 
ATOM   633  H HG23 . THR A 1 44  ? -31.47200 -40.49800 12.97000  1.000 54.07819  ? 44  THR A HG23 1 
ATOM   634  N N    . LYS A 1 45  ? -33.34900 -40.25800 17.43700  1.000 57.58703  ? 45  LYS A N    1 
ATOM   635  C CA   . LYS A 1 45  ? -34.17500 -40.07600 18.62700  1.000 49.54380  ? 45  LYS A CA   1 
ATOM   636  C C    . LYS A 1 45  ? -33.77700 -38.82600 19.40000  1.000 49.00710  ? 45  LYS A C    1 
ATOM   637  O O    . LYS A 1 45  ? -34.64100 -38.16200 19.98200  1.000 50.27217  ? 45  LYS A O    1 
ATOM   638  C CB   . LYS A 1 45  ? -34.07100 -41.30000 19.53400  1.000 58.14038  ? 45  LYS A CB   1 
ATOM   639  C CG   . LYS A 1 45  ? -35.21800 -42.28500 19.43100  1.000 82.64429  ? 45  LYS A CG   1 
ATOM   640  C CD   . LYS A 1 45  ? -34.84400 -43.61700 20.06900  1.000 79.85793  ? 45  LYS A CD   1 
ATOM   641  C CE   . LYS A 1 45  ? -36.01000 -44.58100 20.05200  1.000 97.51376  ? 45  LYS A CE   1 
ATOM   642  N NZ   . LYS A 1 45  ? -36.76000 -44.36600 21.32000  1.000 105.52160 ? 45  LYS A NZ   1 
ATOM   643  H H    . LYS A 1 45  ? -32.95300 -41.02000 17.38700  1.000 67.07819  ? 45  LYS A H    1 
ATOM   644  H HA   . LYS A 1 45  ? -35.10200 -39.98000 18.35700  1.000 55.87819  ? 45  LYS A HA   1 
ATOM   645  H HB2  . LYS A 1 45  ? -33.25600 -41.77800 19.31600  1.000 64.11819  ? 45  LYS A HB2  1 
ATOM   646  H HB3  . LYS A 1 45  ? -34.03100 -40.99600 20.45400  1.000 64.11819  ? 45  LYS A HB3  1 
ATOM   647  H HG2  . LYS A 1 45  ? -35.99200 -41.92900 19.89600  1.000 92.44819  ? 45  LYS A HG2  1 
ATOM   648  H HG3  . LYS A 1 45  ? -35.42700 -42.44100 18.49700  1.000 92.44819  ? 45  LYS A HG3  1 
ATOM   649  H HD2  . LYS A 1 45  ? -34.11200 -44.01600 19.57300  1.000 87.15819  ? 45  LYS A HD2  1 
ATOM   650  H HD3  . LYS A 1 45  ? -34.58400 -43.46900 20.99200  1.000 87.15819  ? 45  LYS A HD3  1 
ATOM   651  H HE2  . LYS A 1 45  ? -36.59300 -44.38900 19.30100  1.000 106.93819 ? 45  LYS A HE2  1 
ATOM   652  H HE3  . LYS A 1 45  ? -35.68800 -45.49600 20.02300  1.000 106.93819 ? 45  LYS A HE3  1 
ATOM   653  H HZ1  . LYS A 1 45  ? -37.46200 -44.91200 21.35400  1.000 114.60819 ? 45  LYS A HZ1  1 
ATOM   654  H HZ2  . LYS A 1 45  ? -36.23200 -44.53000 22.01700  1.000 114.60819 ? 45  LYS A HZ2  1 
ATOM   655  H HZ3  . LYS A 1 45  ? -37.04600 -43.52400 21.36500  1.000 114.60819 ? 45  LYS A HZ3  1 
ATOM   656  N N    . GLN A 1 46  ? -32.49000 -38.47800 19.40200  1.000 55.47285  ? 46  GLN A N    1 
ATOM   657  C CA   . GLN A 1 46  ? -32.01800 -37.27400 20.07100  1.000 54.52052  ? 46  GLN A CA   1 
ATOM   658  C C    . GLN A 1 46  ? -32.07700 -36.02500 19.20000  1.000 47.39349  ? 46  GLN A C    1 
ATOM   659  O O    . GLN A 1 46  ? -31.74200 -34.93900 19.68900  1.000 46.87376  ? 46  GLN A O    1 
ATOM   660  C CB   . GLN A 1 46  ? -30.57300 -37.45000 20.53400  1.000 55.44121  ? 46  GLN A CB   1 
ATOM   661  C CG   . GLN A 1 46  ? -30.37000 -38.56100 21.51100  1.000 55.42863  ? 46  GLN A CG   1 
ATOM   662  C CD   . GLN A 1 46  ? -28.92900 -38.66000 21.97300  1.000 65.22262  ? 46  GLN A CD   1 
ATOM   663  O OE1  . GLN A 1 46  ? -28.31400 -39.71800 21.86400  1.000 73.73925  ? 46  GLN A OE1  1 
ATOM   664  N NE2  . GLN A 1 46  ? -28.37700 -37.55300 22.48000  1.000 80.65779  ? 46  GLN A NE2  1 
ATOM   665  H H    . GLN A 1 46  ? -31.86700 -38.93000 19.01800  1.000 62.35819  ? 46  GLN A H    1 
ATOM   666  H HA   . GLN A 1 46  ? -32.56500 -37.11600 20.85600  1.000 60.97819  ? 46  GLN A HA   1 
ATOM   667  H HB2  . GLN A 1 46  ? -30.01900 -37.63300 19.76000  1.000 61.45819  ? 46  GLN A HB2  1 
ATOM   668  H HB3  . GLN A 1 46  ? -30.28200 -36.62700 20.95700  1.000 61.45819  ? 46  GLN A HB3  1 
ATOM   669  H HG2  . GLN A 1 46  ? -30.92700 -38.40500 22.29000  1.000 59.41819  ? 46  GLN A HG2  1 
ATOM   670  H HG3  . GLN A 1 46  ? -30.61100 -39.40200 21.09100  1.000 59.41819  ? 46  GLN A HG3  1 
ATOM   671  H HE21 . GLN A 1 46  ? -28.83900 -36.83000 22.53800  1.000 88.61819  ? 46  GLN A HE21 1 
ATOM   672  H HE22 . GLN A 1 46  ? -27.56200 -37.56600 22.75300  1.000 88.61819  ? 46  GLN A HE22 1 
ATOM   673  N N    . ILE A 1 47  ? -32.46300 -36.14600 17.93100  1.000 45.70813  ? 47  ILE A N    1 
ATOM   674  C CA   . ILE A 1 47  ? -32.50400 -35.01700 17.00900  1.000 43.01667  ? 47  ILE A CA   1 
ATOM   675  C C    . ILE A 1 47  ? -33.94100 -34.52600 16.90900  1.000 45.32607  ? 47  ILE A C    1 
ATOM   676  O O    . ILE A 1 47  ? -34.86400 -35.32500 16.69500  1.000 50.67973  ? 47  ILE A O    1 
ATOM   677  C CB   . ILE A 1 47  ? -31.95300 -35.40300 15.62600  1.000 35.44486  ? 47  ILE A CB   1 
ATOM   678  C CG1  . ILE A 1 47  ? -30.57000 -36.04600 15.76100  1.000 39.70581  ? 47  ILE A CG1  1 
ATOM   679  C CG2  . ILE A 1 47  ? -31.88300 -34.16500 14.75700  1.000 35.15481  ? 47  ILE A CG2  1 
ATOM   680  C CD1  . ILE A 1 47  ? -29.99400 -36.60000 14.46500  1.000 47.45274  ? 47  ILE A CD1  1 
ATOM   681  H H    . ILE A 1 47  ? -32.71100 -36.88800 17.57400  1.000 57.21819  ? 47  ILE A H    1 
ATOM   682  H HA   . ILE A 1 47  ? -31.96000 -34.29500 17.36000  1.000 55.53819  ? 47  ILE A HA   1 
ATOM   683  H HB   . ILE A 1 47  ? -32.55700 -36.04100 15.21500  1.000 47.91819  ? 47  ILE A HB   1 
ATOM   684  H HG12 . ILE A 1 47  ? -29.95100 -35.37800 16.09500  1.000 52.72819  ? 47  ILE A HG12 1 
ATOM   685  H HG13 . ILE A 1 47  ? -30.62500 -36.78000 16.38900  1.000 52.72819  ? 47  ILE A HG13 1 
ATOM   686  H HG21 . ILE A 1 47  ? -31.49300 -34.39900 13.90100  1.000 48.86819  ? 47  ILE A HG21 1 
ATOM   687  H HG22 . ILE A 1 47  ? -32.77800 -33.81800 14.62300  1.000 48.86819  ? 47  ILE A HG22 1 
ATOM   688  H HG23 . ILE A 1 47  ? -31.33300 -33.50000 15.20000  1.000 48.86819  ? 47  ILE A HG23 1 
ATOM   689  H HD11 . ILE A 1 47  ? -29.18600 -37.09700 14.66600  1.000 63.07819  ? 47  ILE A HD11 1 
ATOM   690  H HD12 . ILE A 1 47  ? -30.64800 -37.18500 14.05300  1.000 63.07819  ? 47  ILE A HD12 1 
ATOM   691  H HD13 . ILE A 1 47  ? -29.79000 -35.86300 13.86900  1.000 63.07819  ? 47  ILE A HD13 1 
ATOM   692  N N    . GLN A 1 48  ? -34.14000 -33.21600 17.09100  1.000 53.44104  ? 48  GLN A N    1 
ATOM   693  C CA   . GLN A 1 48  ? -35.45700 -32.59800 16.98400  1.000 53.36652  ? 48  GLN A CA   1 
ATOM   694  C C    . GLN A 1 48  ? -35.62500 -32.13400 15.54600  1.000 48.38431  ? 48  GLN A C    1 
ATOM   695  O O    . GLN A 1 48  ? -34.96000 -31.18200 15.12100  1.000 48.68243  ? 48  GLN A O    1 
ATOM   696  C CB   . GLN A 1 48  ? -35.64400 -31.39700 17.90400  1.000 62.40271  ? 48  GLN A CB   1 
ATOM   697  C CG   . GLN A 1 48  ? -35.67000 -31.70100 19.37900  1.000 80.29950  ? 48  GLN A CG   1 
ATOM   698  C CD   . GLN A 1 48  ? -35.74200 -30.43000 20.19900  1.000 90.41911  ? 48  GLN A CD   1 
ATOM   699  O OE1  . GLN A 1 48  ? -36.28900 -29.41600 19.76300  1.000 87.71425  ? 48  GLN A OE1  1 
ATOM   700  N NE2  . GLN A 1 48  ? -35.16700 -30.47400 21.39200  1.000 88.76302  ? 48  GLN A NE2  1 
ATOM   701  H H    . GLN A 1 48  ? -33.51300 -32.65800 17.28100  1.000 59.25819  ? 48  GLN A H    1 
ATOM   702  H HA   . GLN A 1 48  ? -36.14400 -33.25300 17.18300  1.000 59.15819  ? 48  GLN A HA   1 
ATOM   703  H HB2  . GLN A 1 48  ? -34.91500 -30.77600 17.74900  1.000 69.03819  ? 48  GLN A HB2  1 
ATOM   704  H HB3  . GLN A 1 48  ? -36.48600 -30.96900 17.68100  1.000 69.03819  ? 48  GLN A HB3  1 
ATOM   705  H HG2  . GLN A 1 48  ? -36.45100 -32.24000 19.58200  1.000 88.46819  ? 48  GLN A HG2  1 
ATOM   706  H HG3  . GLN A 1 48  ? -34.86000 -32.17600 19.62300  1.000 88.46819  ? 48  GLN A HG3  1 
ATOM   707  H HE21 . GLN A 1 48  ? -34.79100 -31.19900 21.66200  1.000 95.78819  ? 48  GLN A HE21 1 
ATOM   708  H HE22 . GLN A 1 48  ? -35.17600 -29.78000 21.90000  1.000 95.78819  ? 48  GLN A HE22 1 
ATOM   709  N N    . ILE A 1 49  ? -36.51000 -32.79800 14.80200  1.000 46.58439  ? 49  ILE A N    1 
ATOM   710  C CA   . ILE A 1 49  ? -36.76700 -32.47500 13.40300  1.000 40.58743  ? 49  ILE A CA   1 
ATOM   711  C C    . ILE A 1 49  ? -38.10600 -31.76300 13.29700  1.000 41.56317  ? 49  ILE A C    1 
ATOM   712  O O    . ILE A 1 49  ? -39.14200 -32.28600 13.72800  1.000 48.87004  ? 49  ILE A O    1 
ATOM   713  C CB   . ILE A 1 49  ? -36.73600 -33.73700 12.52400  1.000 38.63140  ? 49  ILE A CB   1 
ATOM   714  C CG1  . ILE A 1 49  ? -35.50600 -34.56400 12.89200  1.000 36.13469  ? 49  ILE A CG1  1 
ATOM   715  C CG2  . ILE A 1 49  ? -36.71100 -33.36400 11.04600  1.000 48.67664  ? 49  ILE A CG2  1 
ATOM   716  C CD1  . ILE A 1 49  ? -35.21400 -35.72400 11.98400  1.000 29.91490  ? 49  ILE A CD1  1 
ATOM   717  H H    . ILE A 1 49  ? -36.98300 -33.45400 15.09400  1.000 57.96819  ? 49  ILE A H    1 
ATOM   718  H HA   . ILE A 1 49  ? -36.07900 -31.87100 13.08400  1.000 52.06819  ? 49  ILE A HA   1 
ATOM   719  H HB   . ILE A 1 49  ? -37.53100 -34.26300 12.70200  1.000 50.05819  ? 49  ILE A HB   1 
ATOM   720  H HG12 . ILE A 1 49  ? -34.73000 -33.98300 12.88200  1.000 46.82819  ? 49  ILE A HG12 1 
ATOM   721  H HG13 . ILE A 1 49  ? -35.63000 -34.92400 13.78400  1.000 46.82819  ? 49  ILE A HG13 1 
ATOM   722  H HG21 . ILE A 1 49  ? -36.85000 -34.16300 10.51400  1.000 63.29819  ? 49  ILE A HG21 1 
ATOM   723  H HG22 . ILE A 1 49  ? -37.41800 -32.72400 10.86800  1.000 63.29819  ? 49  ILE A HG22 1 
ATOM   724  H HG23 . ILE A 1 49  ? -35.85000 -32.97000 10.83500  1.000 63.29819  ? 49  ILE A HG23 1 
ATOM   725  H HD11 . ILE A 1 49  ? -34.52100 -36.27100 12.38600  1.000 39.61819  ? 49  ILE A HD11 1 
ATOM   726  H HD12 . ILE A 1 49  ? -36.02300 -36.24600 11.87100  1.000 39.61819  ? 49  ILE A HD12 1 
ATOM   727  H HD13 . ILE A 1 49  ? -34.91300 -35.38800 11.12500  1.000 39.61819  ? 49  ILE A HD13 1 
ATOM   728  N N    . HIS A 1 50  ? -38.08400 -30.56500 12.72500  1.000 49.72742  ? 50  HIS A N    1 
ATOM   729  C CA   . HIS A 1 50  ? -39.28700 -29.80400 12.44600  1.000 53.05066  ? 50  HIS A CA   1 
ATOM   730  C C    . HIS A 1 50  ? -39.43400 -29.64700 10.94400  1.000 48.94234  ? 50  HIS A C    1 
ATOM   731  O O    . HIS A 1 50  ? -38.47800 -29.27500 10.25700  1.000 46.13036  ? 50  HIS A O    1 
ATOM   732  C CB   . HIS A 1 50  ? -39.26000 -28.42500 13.08800  1.000 57.38078  ? 50  HIS A CB   1 
ATOM   733  C CG   . HIS A 1 50  ? -40.58200 -27.72400 13.03900  1.000 82.39706  ? 50  HIS A CG   1 
ATOM   734  N ND1  . HIS A 1 50  ? -40.91400 -26.82200 12.05100  1.000 78.46167  ? 50  HIS A ND1  1 
ATOM   735  C CD2  . HIS A 1 50  ? -41.66400 -27.80400 13.85200  1.000 83.16881  ? 50  HIS A CD2  1 
ATOM   736  C CE1  . HIS A 1 50  ? -42.13600 -26.36800 12.26200  1.000 79.81297  ? 50  HIS A CE1  1 
ATOM   737  N NE2  . HIS A 1 50  ? -42.61400 -26.94900 13.34900  1.000 82.44300  ? 50  HIS A NE2  1 
ATOM   738  H H    . HIS A 1 50  ? -37.36200 -30.16400 12.48400  1.000 54.73819  ? 50  HIS A H    1 
ATOM   739  H HA   . HIS A 1 50  ? -40.06100 -30.28200 12.78100  1.000 58.59819  ? 50  HIS A HA   1 
ATOM   740  H HB2  . HIS A 1 50  ? -39.00500 -28.51700 14.01900  1.000 63.37819  ? 50  HIS A HB2  1 
ATOM   741  H HB3  . HIS A 1 50  ? -38.61300 -27.87400 12.62100  1.000 63.37819  ? 50  HIS A HB3  1 
ATOM   742  H HD2  . HIS A 1 50  ? -41.74500 -28.33300 14.61200  1.000 92.57819  ? 50  HIS A HD2  1 
ATOM   743  H HE1  . HIS A 1 50  ? -42.58500 -25.74800 11.73400  1.000 89.65819  ? 50  HIS A HE1  1 
ATOM   744  H HE2  . HIS A 1 50  ? -43.39400 -26.81500 13.68600  1.000 91.65819  ? 50  HIS A HE2  1 
ATOM   745  N N    . LYS A 1 51  ? -40.64100 -29.88500 10.44900  1.000 50.31628  ? 51  LYS A N    1 
ATOM   746  C CA   . LYS A 1 51  ? -40.94600 -29.79000 9.03200   1.000 48.17074  ? 51  LYS A CA   1 
ATOM   747  C C    . LYS A 1 51  ? -41.97800 -28.70100 8.78100   1.000 48.08848  ? 51  LYS A C    1 
ATOM   748  O O    . LYS A 1 51  ? -43.02800 -28.66800 9.43400   1.000 53.87636  ? 51  LYS A O    1 
ATOM   749  C CB   . LYS A 1 51  ? -41.46300 -31.12800 8.50100   1.000 52.09053  ? 51  LYS A CB   1 
ATOM   750  C CG   . LYS A 1 51  ? -40.38400 -32.18100 8.29600   1.000 52.90768  ? 51  LYS A CG   1 
ATOM   751  C CD   . LYS A 1 51  ? -41.01300 -33.50200 7.85400   1.000 67.88133  ? 51  LYS A CD   1 
ATOM   752  C CE   . LYS A 1 51  ? -39.96500 -34.54000 7.41300   1.000 73.73405  ? 51  LYS A CE   1 
ATOM   753  N NZ   . LYS A 1 51  ? -38.54900 -34.04800 7.40100   1.000 78.70008  ? 51  LYS A NZ   1 
ATOM   754  H H    . LYS A 1 51  ? -41.31800 -30.11000 10.93000  1.000 61.42819  ? 51  LYS A H    1 
ATOM   755  H HA   . LYS A 1 51  ? -40.14000 -29.56200 8.54300   1.000 59.49819  ? 51  LYS A HA   1 
ATOM   756  H HB2  . LYS A 1 51  ? -42.10700 -31.48500 9.13300   1.000 63.86819  ? 51  LYS A HB2  1 
ATOM   757  H HB3  . LYS A 1 51  ? -41.89400 -30.97700 7.64500   1.000 63.86819  ? 51  LYS A HB3  1 
ATOM   758  H HG2  . LYS A 1 51  ? -39.77500 -31.87900 7.60400   1.000 65.15819  ? 51  LYS A HG2  1 
ATOM   759  H HG3  . LYS A 1 51  ? -39.90900 -32.32700 9.12900   1.000 65.15819  ? 51  LYS A HG3  1 
ATOM   760  H HD2  . LYS A 1 51  ? -41.51400 -33.87700 8.59500   1.000 82.44819  ? 51  LYS A HD2  1 
ATOM   761  H HD3  . LYS A 1 51  ? -41.60500 -33.33500 7.10400   1.000 82.44819  ? 51  LYS A HD3  1 
ATOM   762  H HE2  . LYS A 1 51  ? -40.00600 -35.29500 8.02100   1.000 89.65819  ? 51  LYS A HE2  1 
ATOM   763  H HE3  . LYS A 1 51  ? -40.18200 -34.83600 6.51600   1.000 89.65819  ? 51  LYS A HE3  1 
ATOM   764  H HZ1  . LYS A 1 51  ? -38.00300 -34.70500 7.15300   1.000 96.53819  ? 51  LYS A HZ1  1 
ATOM   765  H HZ2  . LYS A 1 51  ? -38.46600 -33.37200 6.82800   1.000 96.53819  ? 51  LYS A HZ2  1 
ATOM   766  H HZ3  . LYS A 1 51  ? -38.31600 -33.77000 8.21400   1.000 96.53819  ? 51  LYS A HZ3  1 
ATOM   767  N N    . SER A 1 52  ? -41.67000 -27.81800 7.81800   1.000 55.51769  ? 52  SER A N    1 
ATOM   768  C CA   . SER A 1 52  ? -42.59700 -26.81200 7.28400   1.000 49.58799  ? 52  SER A CA   1 
ATOM   769  C C    . SER A 1 52  ? -42.70000 -27.04700 5.77400   1.000 46.10393  ? 52  SER A C    1 
ATOM   770  O O    . SER A 1 52  ? -41.98100 -26.42800 4.98600   1.000 48.01888  ? 52  SER A O    1 
ATOM   771  C CB   . SER A 1 52  ? -42.12200 -25.39700 7.60000   1.000 54.94198  ? 52  SER A CB   1 
ATOM   772  O OG   . SER A 1 52  ? -42.77500 -24.44400 6.77500   1.000 68.15144  ? 52  SER A OG   1 
ATOM   773  H H    . SER A 1 52  ? -40.89600 -27.78400 7.44500   1.000 65.29819  ? 52  SER A H    1 
ATOM   774  H HA   . SER A 1 52  ? -43.47500 -26.93800 7.67700   1.000 57.92819  ? 52  SER A HA   1 
ATOM   775  H HB2  . SER A 1 52  ? -42.32000 -25.19800 8.52900   1.000 64.41819  ? 52  SER A HB2  1 
ATOM   776  H HB3  . SER A 1 52  ? -41.16600 -25.34400 7.44700   1.000 64.41819  ? 52  SER A HB3  1 
ATOM   777  H HG   . SER A 1 52  ? -42.51300 -23.67000 6.96700   1.000 80.10819  ? 52  SER A HG   1 
ATOM   778  N N    . GLY A 1 53  ? -43.59500 -27.94700 5.37500   1.000 39.35993  ? 53  GLY A N    1 
ATOM   779  C CA   . GLY A 1 53  ? -43.69300 -28.34700 3.98500   1.000 34.33842  ? 53  GLY A CA   1 
ATOM   780  C C    . GLY A 1 53  ? -42.46300 -29.07300 3.47600   1.000 39.78940  ? 53  GLY A C    1 
ATOM   781  O O    . GLY A 1 53  ? -42.23500 -30.24000 3.81500   1.000 52.59556  ? 53  GLY A O    1 
ATOM   782  H H    . GLY A 1 53  ? -44.15700 -28.33900 5.89500   1.000 51.55819  ? 53  GLY A H    1 
ATOM   783  H HA2  . GLY A 1 53  ? -44.45800 -28.93200 3.87400   1.000 45.53819  ? 53  GLY A HA2  1 
ATOM   784  H HA3  . GLY A 1 53  ? -43.83000 -27.56000 3.43500   1.000 45.53819  ? 53  GLY A HA3  1 
ATOM   785  N N    . GLU A 1 54  ? -41.67100 -28.39200 2.64100   1.000 52.90658  ? 54  GLU A N    1 
ATOM   786  C CA   . GLU A 1 54  ? -40.41700 -28.93100 2.12800   1.000 45.64372  ? 54  GLU A CA   1 
ATOM   787  C C    . GLU A 1 54  ? -39.19700 -28.37300 2.84500   1.000 42.16560  ? 54  GLU A C    1 
ATOM   788  O O    . GLU A 1 54  ? -38.08800 -28.84700 2.58700   1.000 46.64136  ? 54  GLU A O    1 
ATOM   789  C CB   . GLU A 1 54  ? -40.28300 -28.66200 0.62200   1.000 42.50858  ? 54  GLU A CB   1 
ATOM   790  C CG   . GLU A 1 54  ? -41.22100 -29.52800 -0.22200  1.000 55.64711  ? 54  GLU A CG   1 
ATOM   791  C CD   . GLU A 1 54  ? -40.82800 -30.99600 -0.25700  1.000 58.14819  ? 54  GLU A CD   1 
ATOM   792  O OE1  . GLU A 1 54  ? -39.60900 -31.25600 -0.39800  1.000 47.51422  ? 54  GLU A OE1  1 
ATOM   793  O OE2  . GLU A 1 54  ? -41.73800 -31.86500 -0.16000  1.000 58.44588  ? 54  GLU A OE2  1 
ATOM   794  H H    . GLU A 1 54  ? -41.84600 -27.60000 2.35400   1.000 62.87819  ? 54  GLU A H    1 
ATOM   795  H HA   . GLU A 1 54  ? -40.41600 -29.89200 2.25500   1.000 54.61819  ? 54  GLU A HA   1 
ATOM   796  H HB2  . GLU A 1 54  ? -40.49600 -27.73200 0.44700   1.000 50.62819  ? 54  GLU A HB2  1 
ATOM   797  H HB3  . GLU A 1 54  ? -39.37200 -28.85100 0.34700   1.000 50.62819  ? 54  GLU A HB3  1 
ATOM   798  H HG2  . GLU A 1 54  ? -42.11700 -29.47000 0.14500   1.000 65.49819  ? 54  GLU A HG2  1 
ATOM   799  H HG3  . GLU A 1 54  ? -41.21400 -29.19400 -1.13200  1.000 65.49819  ? 54  GLU A HG3  1 
ATOM   800  N N    . PHE A 1 55  ? -39.36600 -27.37700 3.71400   1.000 37.53239  ? 55  PHE A N    1 
ATOM   801  C CA   . PHE A 1 55  ? -38.27400 -26.85100 4.52500   1.000 35.17119  ? 55  PHE A CA   1 
ATOM   802  C C    . PHE A 1 55  ? -38.16300 -27.72700 5.76800   1.000 36.02087  ? 55  PHE A C    1 
ATOM   803  O O    . PHE A 1 55  ? -39.12200 -27.83500 6.54000   1.000 35.88938  ? 55  PHE A O    1 
ATOM   804  C CB   . PHE A 1 55  ? -38.52100 -25.38400 4.88700   1.000 42.22217  ? 55  PHE A CB   1 
ATOM   805  C CG   . PHE A 1 55  ? -37.35900 -24.72500 5.58500   1.000 37.00982  ? 55  PHE A CG   1 
ATOM   806  C CD1  . PHE A 1 55  ? -37.24400 -24.78800 6.95400   1.000 33.29535  ? 55  PHE A CD1  1 
ATOM   807  C CD2  . PHE A 1 55  ? -36.37800 -24.05600 4.87400   1.000 34.20228  ? 55  PHE A CD2  1 
ATOM   808  C CE1  . PHE A 1 55  ? -36.19400 -24.20000 7.60100   1.000 33.32524  ? 55  PHE A CE1  1 
ATOM   809  C CE2  . PHE A 1 55  ? -35.30500 -23.46800 5.53800   1.000 30.79386  ? 55  PHE A CE2  1 
ATOM   810  C CZ   . PHE A 1 55  ? -35.22600 -23.54000 6.89600   1.000 25.60066  ? 55  PHE A CZ   1 
ATOM   811  H H    . PHE A 1 55  ? -40.11800 -26.98300 3.85300   1.000 53.63819  ? 55  PHE A H    1 
ATOM   812  H HA   . PHE A 1 55  ? -37.44200 -26.91100 4.02900   1.000 51.15819  ? 55  PHE A HA   1 
ATOM   813  H HB2  . PHE A 1 55  ? -38.69800 -24.88700 4.07300   1.000 59.37819  ? 55  PHE A HB2  1 
ATOM   814  H HB3  . PHE A 1 55  ? -39.28900 -25.33300 5.47700   1.000 59.37819  ? 55  PHE A HB3  1 
ATOM   815  H HD1  . PHE A 1 55  ? -37.89500 -25.23300 7.44800   1.000 48.41819  ? 55  PHE A HD1  1 
ATOM   816  H HD2  . PHE A 1 55  ? -36.43100 -24.00600 3.94700   1.000 50.02819  ? 55  PHE A HD2  1 
ATOM   817  H HE1  . PHE A 1 55  ? -36.13600 -24.25200 8.52800   1.000 48.28819  ? 55  PHE A HE1  1 
ATOM   818  H HE2  . PHE A 1 55  ? -34.65000 -23.01600 5.05700   1.000 45.79819  ? 55  PHE A HE2  1 
ATOM   819  H HZ   . PHE A 1 55  ? -34.51300 -23.14300 7.34300   1.000 39.22819  ? 55  PHE A HZ   1 
ATOM   820  N N    . CYS A 1 56  ? -37.02100 -28.39100 5.93700   1.000 41.99444  ? 56  CYS A N    1 
ATOM   821  C CA   . CYS A 1 56  ? -36.82200 -29.28900 7.06500   1.000 41.99814  ? 56  CYS A CA   1 
ATOM   822  C C    . CYS A 1 56  ? -35.65500 -28.82200 7.92400   1.000 42.64803  ? 56  CYS A C    1 
ATOM   823  O O    . CYS A 1 56  ? -34.58500 -28.50000 7.40500   1.000 39.19893  ? 56  CYS A O    1 
ATOM   824  C CB   . CYS A 1 56  ? -36.56900 -30.72400 6.60900   1.000 44.71556  ? 56  CYS A CB   1 
ATOM   825  S SG   . CYS A 1 56  ? -36.67300 -31.84800 8.02000   1.000 55.45599  ? 56  CYS A SG   1 
ATOM   826  H H    . CYS A 1 56  ? -36.34500 -28.33600 5.40800   1.000 53.12819  ? 56  CYS A H    1 
ATOM   827  H HA   . CYS A 1 56  ? -37.61700 -29.28900 7.61900   1.000 52.83819  ? 56  CYS A HA   1 
ATOM   828  H HB2  . CYS A 1 56  ? -37.24100 -30.98200 5.95900   1.000 56.06819  ? 56  CYS A HB2  1 
ATOM   829  H HB3  . CYS A 1 56  ? -35.68100 -30.79100 6.22600   1.000 56.06819  ? 56  CYS A HB3  1 
ATOM   830  H HG   . CYS A 1 56  ? -35.84500 -31.53600 8.83100   1.000 68.22819  ? 56  CYS A HG   1 
ATOM   831  N N    . ARG A 1 57  ? -35.85500 -28.83700 9.24200   1.000 37.87311  ? 57  ARG A N    1 
ATOM   832  C CA   . ARG A 1 57  ? -34.94500 -28.22400 10.20700  1.000 34.42853  ? 57  ARG A CA   1 
ATOM   833  C C    . ARG A 1 57  ? -34.53600 -29.27400 11.23000  1.000 35.40089  ? 57  ARG A C    1 
ATOM   834  O O    . ARG A 1 57  ? -35.38500 -29.81000 11.94500  1.000 37.00836  ? 57  ARG A O    1 
ATOM   835  C CB   . ARG A 1 57  ? -35.63200 -27.04100 10.88700  1.000 42.46088  ? 57  ARG A CB   1 
ATOM   836  C CG   . ARG A 1 57  ? -34.73900 -26.16100 11.73900  1.000 58.46043  ? 57  ARG A CG   1 
ATOM   837  C CD   . ARG A 1 57  ? -35.55900 -25.28000 12.68800  1.000 51.39855  ? 57  ARG A CD   1 
ATOM   838  N NE   . ARG A 1 57  ? -36.33300 -24.24900 12.00000  1.000 75.95670  ? 57  ARG A NE   1 
ATOM   839  C CZ   . ARG A 1 57  ? -36.10800 -22.94100 12.09300  1.000 74.04622  ? 57  ARG A CZ   1 
ATOM   840  N NH1  . ARG A 1 57  ? -35.13500 -22.45200 12.85100  1.000 73.32956  ? 57  ARG A NH1  1 
ATOM   841  N NH2  . ARG A 1 57  ? -36.89200 -22.09900 11.42400  1.000 70.67423  ? 57  ARG A NH2  1 
ATOM   842  H H    . ARG A 1 57  ? -36.53600 -29.21000 9.61200   1.000 50.39819  ? 57  ARG A H    1 
ATOM   843  H HA   . ARG A 1 57  ? -34.15000 -27.90400 9.75300   1.000 45.90819  ? 57  ARG A HA   1 
ATOM   844  H HB2  . ARG A 1 57  ? -36.02300 -26.47800 10.20000  1.000 54.91819  ? 57  ARG A HB2  1 
ATOM   845  H HB3  . ARG A 1 57  ? -36.33400 -27.38500 11.46100  1.000 54.91819  ? 57  ARG A HB3  1 
ATOM   846  H HG2  . ARG A 1 57  ? -34.16100 -26.72600 12.27400  1.000 73.50819  ? 57  ARG A HG2  1 
ATOM   847  H HG3  . ARG A 1 57  ? -34.21100 -25.58400 11.16500  1.000 73.50819  ? 57  ARG A HG3  1 
ATOM   848  H HD2  . ARG A 1 57  ? -36.18800 -25.84500 13.16400  1.000 63.96819  ? 57  ARG A HD2  1 
ATOM   849  H HD3  . ARG A 1 57  ? -34.95900 -24.86300 13.32200  1.000 63.96819  ? 57  ARG A HD3  1 
ATOM   850  H HE   . ARG A 1 57  ? -36.98200 -24.50700 11.49800  1.000 93.60819  ? 57  ARG A HE   1 
ATOM   851  H HH11 . ARG A 1 57  ? -34.61800 -22.97500 13.29300  1.000 89.21819  ? 57  ARG A HH11 1 
ATOM   852  H HH12 . ARG A 1 57  ? -35.01600 -21.60100 12.89300  1.000 89.21819  ? 57  ARG A HH12 1 
ATOM   853  H HH21 . ARG A 1 57  ? -37.52800 -22.40300 10.93100  1.000 86.83819  ? 57  ARG A HH21 1 
ATOM   854  H HH22 . ARG A 1 57  ? -36.75800 -21.25100 11.47800  1.000 86.83819  ? 57  ARG A HH22 1 
ATOM   855  N N    . LEU A 1 58  ? -33.25200 -29.58600 11.30500  1.000 40.22842  ? 58  LEU A N    1 
ATOM   856  C CA   . LEU A 1 58  ? -32.75700 -30.57900 12.24800  1.000 38.41313  ? 58  LEU A CA   1 
ATOM   857  C C    . LEU A 1 58  ? -31.90000 -29.87200 13.29500  1.000 44.21802  ? 58  LEU A C    1 
ATOM   858  O O    . LEU A 1 58  ? -30.84000 -29.32900 12.96500  1.000 37.62505  ? 58  LEU A O    1 
ATOM   859  C CB   . LEU A 1 58  ? -31.94500 -31.66400 11.53600  1.000 36.29725  ? 58  LEU A CB   1 
ATOM   860  C CG   . LEU A 1 58  ? -32.56400 -32.69500 10.58500  1.000 33.56260  ? 58  LEU A CG   1 
ATOM   861  C CD1  . LEU A 1 58  ? -32.74000 -32.07700 9.21200   1.000 54.11798  ? 58  LEU A CD1  1 
ATOM   862  C CD2  . LEU A 1 58  ? -31.70600 -33.95600 10.50000  1.000 36.56221  ? 58  LEU A CD2  1 
ATOM   863  H H    . LEU A 1 58  ? -32.63900 -29.23300 10.81600  1.000 50.97819  ? 58  LEU A H    1 
ATOM   864  H HA   . LEU A 1 58  ? -33.50200 -31.00400 12.70000  1.000 48.07819  ? 58  LEU A HA   1 
ATOM   865  H HB2  . LEU A 1 58  ? -31.26400 -31.20600 11.01900  1.000 45.97819  ? 58  LEU A HB2  1 
ATOM   866  H HB3  . LEU A 1 58  ? -31.50200 -32.17900 12.22900  1.000 45.97819  ? 58  LEU A HB3  1 
ATOM   867  H HG   . LEU A 1 58  ? -33.44000 -32.94800 10.91700  1.000 43.05819  ? 58  LEU A HG   1 
ATOM   868  H HD11 . LEU A 1 58  ? -33.14100 -32.73300 8.62100   1.000 68.58819  ? 58  LEU A HD11 1 
ATOM   869  H HD12 . LEU A 1 58  ? -33.31800 -31.30200 9.28700   1.000 68.58819  ? 58  LEU A HD12 1 
ATOM   870  H HD13 . LEU A 1 58  ? -31.87100 -31.81200 8.87100   1.000 68.58819  ? 58  LEU A HD13 1 
ATOM   871  H HD21 . LEU A 1 58  ? -32.11800 -34.57600 9.87800   1.000 46.41819  ? 58  LEU A HD21 1 
ATOM   872  H HD22 . LEU A 1 58  ? -30.82000 -33.71400 10.18800  1.000 46.41819  ? 58  LEU A HD22 1 
ATOM   873  H HD23 . LEU A 1 58  ? -31.64900 -34.35900 11.38100  1.000 46.41819  ? 58  LEU A HD23 1 
ATOM   874  N N    . ARG A 1 59  ? -32.36800 -29.86300 14.54600  1.000 51.26592  ? 59  ARG A N    1 
ATOM   875  C CA   . ARG A 1 59  ? -31.63700 -29.28900 15.67200  1.000 52.82338  ? 59  ARG A CA   1 
ATOM   876  C C    . ARG A 1 59  ? -30.97400 -30.42300 16.44600  1.000 52.19656  ? 59  ARG A C    1 
ATOM   877  O O    . ARG A 1 59  ? -31.65400 -31.34800 16.90200  1.000 50.60550  ? 59  ARG A O    1 
ATOM   878  C CB   . ARG A 1 59  ? -32.57800 -28.49600 16.57700  1.000 53.97630  ? 59  ARG A CB   1 
ATOM   879  C CG   . ARG A 1 59  ? -31.99600 -28.13700 17.91800  1.000 62.36543  ? 59  ARG A CG   1 
ATOM   880  C CD   . ARG A 1 59  ? -31.13600 -26.89100 17.81600  1.000 79.14332  ? 59  ARG A CD   1 
ATOM   881  N NE   . ARG A 1 59  ? -31.82400 -25.75900 17.20200  1.000 70.91347  ? 59  ARG A NE   1 
ATOM   882  C CZ   . ARG A 1 59  ? -31.24800 -24.59000 16.95700  1.000 75.99362  ? 59  ARG A CZ   1 
ATOM   883  N NH1  . ARG A 1 59  ? -29.97100 -24.37600 17.23800  1.000 71.68881  ? 59  ARG A NH1  1 
ATOM   884  N NH2  . ARG A 1 59  ? -31.97200 -23.60600 16.42900  1.000 86.83104  ? 59  ARG A NH2  1 
ATOM   885  H H    . ARG A 1 59  ? -33.12900 -30.19400 14.77000  1.000 58.33819  ? 59  ARG A H    1 
ATOM   886  H HA   . ARG A 1 59  ? -30.94700 -28.69200 15.34400  1.000 59.03819  ? 59  ARG A HA   1 
ATOM   887  H HB2  . ARG A 1 59  ? -32.83300 -27.68000 16.12000  1.000 59.31819  ? 59  ARG A HB2  1 
ATOM   888  H HB3  . ARG A 1 59  ? -33.36900 -29.03400 16.74000  1.000 59.31819  ? 59  ARG A HB3  1 
ATOM   889  H HG2  . ARG A 1 59  ? -32.72400 -27.94100 18.52800  1.000 67.67819  ? 59  ARG A HG2  1 
ATOM   890  H HG3  . ARG A 1 59  ? -31.45500 -28.85400 18.27800  1.000 67.67819  ? 59  ARG A HG3  1 
ATOM   891  H HD2  . ARG A 1 59  ? -30.86200 -26.62500 18.70800  1.000 87.67819  ? 59  ARG A HD2  1 
ATOM   892  H HD3  . ARG A 1 59  ? -30.35500 -27.09200 17.27700  1.000 87.67819  ? 59  ARG A HD3  1 
ATOM   893  H HE   . ARG A 1 59  ? -32.67900 -25.80600 17.12600  1.000 78.33819  ? 59  ARG A HE   1 
ATOM   894  H HH11 . ARG A 1 59  ? -29.49300 -25.00200 17.58200  1.000 78.52819  ? 59  ARG A HH11 1 
ATOM   895  H HH12 . ARG A 1 59  ? -29.61800 -23.61000 17.07200  1.000 78.52819  ? 59  ARG A HH12 1 
ATOM   896  H HH21 . ARG A 1 59  ? -32.80200 -23.73500 16.24300  1.000 97.60819  ? 59  ARG A HH21 1 
ATOM   897  H HH22 . ARG A 1 59  ? -31.60800 -22.84400 16.26600  1.000 97.60819  ? 59  ARG A HH22 1 
ATOM   898  N N    . PHE A 1 60  ? -29.66800 -30.35600 16.58900  1.000 52.15076  ? 60  PHE A N    1 
ATOM   899  C CA   . PHE A 1 60  ? -28.92300 -31.42400 17.23400  1.000 51.76026  ? 60  PHE A CA   1 
ATOM   900  C C    . PHE A 1 60  ? -28.72800 -31.13000 18.71200  1.000 51.34958  ? 60  PHE A C    1 
ATOM   901  O O    . PHE A 1 60  ? -28.67100 -29.96900 19.12900  1.000 46.64679  ? 60  PHE A O    1 
ATOM   902  C CB   . PHE A 1 60  ? -27.55900 -31.61300 16.55200  1.000 57.57050  ? 60  PHE A CB   1 
ATOM   903  C CG   . PHE A 1 60  ? -27.65400 -32.23100 15.19100  1.000 45.31179  ? 60  PHE A CG   1 
ATOM   904  C CD1  . PHE A 1 60  ? -27.95700 -31.46200 14.08000  1.000 41.68356  ? 60  PHE A CD1  1 
ATOM   905  C CD2  . PHE A 1 60  ? -27.48600 -33.58700 15.03000  1.000 38.67004  ? 60  PHE A CD2  1 
ATOM   906  C CE1  . PHE A 1 60  ? -28.07400 -32.04300 12.83300  1.000 38.27281  ? 60  PHE A CE1  1 
ATOM   907  C CE2  . PHE A 1 60  ? -27.60300 -34.16100 13.79500  1.000 41.88901  ? 60  PHE A CE2  1 
ATOM   908  C CZ   . PHE A 1 60  ? -27.89800 -33.39200 12.69500  1.000 36.51696  ? 60  PHE A CZ   1 
ATOM   909  H H    . PHE A 1 60  ? -29.18200 -29.69900 16.32100  1.000 63.42819  ? 60  PHE A H    1 
ATOM   910  H HA   . PHE A 1 60  ? -29.42300 -32.25000 17.14300  1.000 62.07819  ? 60  PHE A HA   1 
ATOM   911  H HB2  . PHE A 1 60  ? -27.13500 -30.74600 16.45500  1.000 69.65819  ? 60  PHE A HB2  1 
ATOM   912  H HB3  . PHE A 1 60  ? -27.00800 -32.18900 17.10300  1.000 69.65819  ? 60  PHE A HB3  1 
ATOM   913  H HD1  . PHE A 1 60  ? -28.08300 -30.54500 14.17500  1.000 53.26819  ? 60  PHE A HD1  1 
ATOM   914  H HD2  . PHE A 1 60  ? -27.29200 -34.11800 15.76800  1.000 48.36819  ? 60  PHE A HD2  1 
ATOM   915  H HE1  . PHE A 1 60  ? -28.27000 -31.51900 12.09000  1.000 50.22819  ? 60  PHE A HE1  1 
ATOM   916  H HE2  . PHE A 1 60  ? -27.48000 -35.07800 13.69800  1.000 53.27819  ? 60  PHE A HE2  1 
ATOM   917  H HZ   . PHE A 1 60  ? -27.96700 -33.78700 11.85600  1.000 47.97819  ? 60  PHE A HZ   1 
ATOM   918  N N    . PRO A 1 61  ? -28.60300 -32.17300 19.53400  1.000 48.69070  ? 61  PRO A N    1 
ATOM   919  C CA   . PRO A 1 61  ? -28.52600 -31.95200 20.98700  1.000 48.25496  ? 61  PRO A CA   1 
ATOM   920  C C    . PRO A 1 61  ? -27.26500 -31.23300 21.42700  1.000 52.74846  ? 61  PRO A C    1 
ATOM   921  O O    . PRO A 1 61  ? -27.25500 -30.61500 22.49800  1.000 52.66442  ? 61  PRO A O    1 
ATOM   922  C CB   . PRO A 1 61  ? -28.59200 -33.37800 21.56000  1.000 56.62199  ? 61  PRO A CB   1 
ATOM   923  C CG   . PRO A 1 61  ? -28.12300 -34.27000 20.44500  1.000 58.71232  ? 61  PRO A CG   1 
ATOM   924  C CD   . PRO A 1 61  ? -28.55700 -33.60100 19.17000  1.000 49.57014  ? 61  PRO A CD   1 
ATOM   925  H HA   . PRO A 1 61  ? -29.30000 -31.45200 21.29000  1.000 58.76819  ? 61  PRO A HA   1 
ATOM   926  H HB2  . PRO A 1 61  ? -28.00300 -33.45000 22.32700  1.000 67.77819  ? 61  PRO A HB2  1 
ATOM   927  H HB3  . PRO A 1 61  ? -29.50600 -33.58900 21.80700  1.000 67.77819  ? 61  PRO A HB3  1 
ATOM   928  H HG2  . PRO A 1 61  ? -27.15700 -34.34800 20.47700  1.000 71.80819  ? 61  PRO A HG2  1 
ATOM   929  H HG3  . PRO A 1 61  ? -28.53800 -35.14200 20.53000  1.000 71.80819  ? 61  PRO A HG3  1 
ATOM   930  H HD2  . PRO A 1 61  ? -27.90200 -33.74900 18.47100  1.000 62.84819  ? 61  PRO A HD2  1 
ATOM   931  H HD3  . PRO A 1 61  ? -29.43700 -33.91200 18.90700  1.000 62.84819  ? 61  PRO A HD3  1 
ATOM   932  N N    . LYS A 1 62  ? -26.20600 -31.29200 20.62700  1.000 66.52048  ? 62  LYS A N    1 
ATOM   933  C CA   . LYS A 1 62  ? -24.86000 -30.88900 20.99000  1.000 62.72664  ? 62  LYS A CA   1 
ATOM   934  C C    . LYS A 1 62  ? -24.24400 -30.39600 19.69200  1.000 59.90287  ? 62  LYS A C    1 
ATOM   935  O O    . LYS A 1 62  ? -24.47500 -31.00700 18.64100  1.000 57.78352  ? 62  LYS A O    1 
ATOM   936  C CB   . LYS A 1 62  ? -24.03300 -32.04700 21.53300  1.000 74.20947  ? 62  LYS A CB   1 
ATOM   937  C CG   . LYS A 1 62  ? -24.71300 -32.80000 22.61600  1.000 82.43766  ? 62  LYS A CG   1 
ATOM   938  C CD   . LYS A 1 62  ? -24.04400 -34.13600 22.85300  1.000 93.34868  ? 62  LYS A CD   1 
ATOM   939  C CE   . LYS A 1 62  ? -22.57300 -34.00100 23.23000  1.000 99.10408  ? 62  LYS A CE   1 
ATOM   940  N NZ   . LYS A 1 62  ? -21.81300 -35.26400 22.96600  1.000 114.25373 ? 62  LYS A NZ   1 
ATOM   941  H H    . LYS A 1 62  ? -26.25200 -31.58100 19.81900  1.000 71.78819  ? 62  LYS A H    1 
ATOM   942  H HA   . LYS A 1 62  ? -24.88600 -30.17200 21.64200  1.000 66.24819  ? 62  LYS A HA   1 
ATOM   943  H HB2  . LYS A 1 62  ? -23.84000 -32.66500 20.81100  1.000 78.91819  ? 62  LYS A HB2  1 
ATOM   944  H HB3  . LYS A 1 62  ? -23.20800 -31.68300 21.88900  1.000 78.91819  ? 62  LYS A HB3  1 
ATOM   945  H HG2  . LYS A 1 62  ? -24.67500 -32.28800 23.43900  1.000 87.19819  ? 62  LYS A HG2  1 
ATOM   946  H HG3  . LYS A 1 62  ? -25.63200 -32.97900 22.37100  1.000 87.19819  ? 62  LYS A HG3  1 
ATOM   947  H HD2  . LYS A 1 62  ? -24.49900 -34.59300 23.57800  1.000 99.56819  ? 62  LYS A HD2  1 
ATOM   948  H HD3  . LYS A 1 62  ? -24.09800 -34.66500 22.04200  1.000 99.56819  ? 62  LYS A HD3  1 
ATOM   949  H HE2  . LYS A 1 62  ? -22.14900 -33.30000 22.71600  1.000 105.27819 ? 62  LYS A HE2  1 
ATOM   950  H HE3  . LYS A 1 62  ? -22.50700 -33.80400 24.17800  1.000 105.27819 ? 62  LYS A HE3  1 
ATOM   951  H HZ1  . LYS A 1 62  ? -20.95900 -35.15800 23.19400  1.000 123.43819 ? 62  LYS A HZ1  1 
ATOM   952  H HZ2  . LYS A 1 62  ? -22.15900 -35.93200 23.44200  1.000 123.43819 ? 62  LYS A HZ2  1 
ATOM   953  H HZ3  . LYS A 1 62  ? -21.85800 -35.47100 22.10200  1.000 123.43819 ? 62  LYS A HZ3  1 
ATOM   954  N N    . PRO A 1 63  ? -23.46200 -29.32100 19.71200  1.000 51.55373  ? 63  PRO A N    1 
ATOM   955  C CA   . PRO A 1 63  ? -23.05400 -28.71800 18.43200  1.000 51.58053  ? 63  PRO A CA   1 
ATOM   956  C C    . PRO A 1 63  ? -22.19000 -29.67400 17.61700  1.000 54.00924  ? 63  PRO A C    1 
ATOM   957  O O    . PRO A 1 63  ? -21.22000 -30.23600 18.11900  1.000 46.88597  ? 63  PRO A O    1 
ATOM   958  C CB   . PRO A 1 63  ? -22.29400 -27.45700 18.86400  1.000 43.87886  ? 63  PRO A CB   1 
ATOM   959  C CG   . PRO A 1 63  ? -21.89200 -27.69600 20.25300  1.000 42.84848  ? 63  PRO A CG   1 
ATOM   960  C CD   . PRO A 1 63  ? -22.97400 -28.54300 20.86400  1.000 44.47713  ? 63  PRO A CD   1 
ATOM   961  H HA   . PRO A 1 63  ? -23.83300 -28.46400 17.91300  1.000 65.77819  ? 63  PRO A HA   1 
ATOM   962  H HB2  . PRO A 1 63  ? -21.51500 -27.33700 18.29900  1.000 55.19819  ? 63  PRO A HB2  1 
ATOM   963  H HB3  . PRO A 1 63  ? -22.88100 -26.68700 18.80600  1.000 55.19819  ? 63  PRO A HB3  1 
ATOM   964  H HG2  . PRO A 1 63  ? -21.04400 -28.16600 20.26800  1.000 51.39819  ? 63  PRO A HG2  1 
ATOM   965  H HG3  . PRO A 1 63  ? -21.82000 -26.84900 20.71900  1.000 51.39819  ? 63  PRO A HG3  1 
ATOM   966  H HD2  . PRO A 1 63  ? -22.60400 -29.13200 21.54000  1.000 53.58819  ? 63  PRO A HD2  1 
ATOM   967  H HD3  . PRO A 1 63  ? -23.68200 -27.98500 21.22200  1.000 53.58819  ? 63  PRO A HD3  1 
ATOM   968  N N    . ILE A 1 64  ? -22.56300 -29.87600 16.34800  1.000 55.56849  ? 64  ILE A N    1 
ATOM   969  C CA   . ILE A 1 64  ? -21.81100 -30.80100 15.49900  1.000 49.16848  ? 64  ILE A CA   1 
ATOM   970  C C    . ILE A 1 64  ? -20.61100 -30.10800 14.86100  1.000 46.60067  ? 64  ILE A C    1 
ATOM   971  O O    . ILE A 1 64  ? -19.52900 -30.69400 14.74700  1.000 61.82060  ? 64  ILE A O    1 
ATOM   972  C CB   . ILE A 1 64  ? -22.73700 -31.41400 14.43200  1.000 42.71323  ? 64  ILE A CB   1 
ATOM   973  C CG1  . ILE A 1 64  ? -23.97900 -32.01500 15.09200  1.000 44.63891  ? 64  ILE A CG1  1 
ATOM   974  C CG2  . ILE A 1 64  ? -21.98700 -32.42900 13.60500  1.000 43.91397  ? 64  ILE A CG2  1 
ATOM   975  C CD1  . ILE A 1 64  ? -23.69600 -33.06300 16.11000  1.000 47.35155  ? 64  ILE A CD1  1 
ATOM   976  H H    . ILE A 1 64  ? -23.23300 -29.49800 15.96400  1.000 65.84819  ? 64  ILE A H    1 
ATOM   977  H HA   . ILE A 1 64  ? -21.47000 -31.52400 16.04800  1.000 58.85819  ? 64  ILE A HA   1 
ATOM   978  H HB   . ILE A 1 64  ? -23.02600 -30.70100 13.84200  1.000 52.66819  ? 64  ILE A HB   1 
ATOM   979  H HG12 . ILE A 1 64  ? -24.47800 -31.30700 15.52800  1.000 54.80819  ? 64  ILE A HG12 1 
ATOM   980  H HG13 . ILE A 1 64  ? -24.52700 -32.42000 14.40200  1.000 54.80819  ? 64  ILE A HG13 1 
ATOM   981  H HG21 . ILE A 1 64  ? -22.62300 -32.93100 13.07100  1.000 54.50819  ? 64  ILE A HG21 1 
ATOM   982  H HG22 . ILE A 1 64  ? -21.36200 -31.96700 13.02500  1.000 54.50819  ? 64  ILE A HG22 1 
ATOM   983  H HG23 . ILE A 1 64  ? -21.50900 -33.02900 14.19900  1.000 54.50819  ? 64  ILE A HG23 1 
ATOM   984  H HD11 . ILE A 1 64  ? -24.53800 -33.42800 16.42000  1.000 56.79819  ? 64  ILE A HD11 1 
ATOM   985  H HD12 . ILE A 1 64  ? -23.16000 -33.76300 15.70600  1.000 56.79819  ? 64  ILE A HD12 1 
ATOM   986  H HD13 . ILE A 1 64  ? -23.21800 -32.66600 16.85400  1.000 56.79819  ? 64  ILE A HD13 1 
ATOM   987  N N    . ARG A 1 65  ? -20.77700 -28.86100 14.43900  1.000 44.42628  ? 65  ARG A N    1 
ATOM   988  C CA   . ARG A 1 65  ? -19.75100 -28.11500 13.71500  1.000 53.03548  ? 65  ARG A CA   1 
ATOM   989  C C    . ARG A 1 65  ? -19.29000 -26.94900 14.59400  1.000 58.93543  ? 65  ARG A C    1 
ATOM   990  O O    . ARG A 1 65  ? -19.77600 -25.82200 14.46900  1.000 48.71784  ? 65  ARG A O    1 
ATOM   991  C CB   . ARG A 1 65  ? -20.29800 -27.63800 12.36100  1.000 41.76711  ? 65  ARG A CB   1 
ATOM   992  C CG   . ARG A 1 65  ? -20.60200 -28.74000 11.34800  1.000 42.92370  ? 65  ARG A CG   1 
ATOM   993  C CD   . ARG A 1 65  ? -19.32700 -29.22600 10.63200  1.000 45.04433  ? 65  ARG A CD   1 
ATOM   994  N NE   . ARG A 1 65  ? -18.57300 -28.13700 10.01700  1.000 36.46868  ? 65  ARG A NE   1 
ATOM   995  C CZ   . ARG A 1 65  ? -18.70800 -27.74800 8.75500   1.000 38.52574  ? 65  ARG A CZ   1 
ATOM   996  N NH1  . ARG A 1 65  ? -19.53000 -28.36600 7.92200   1.000 39.31107  ? 65  ARG A NH1  1 
ATOM   997  N NH2  . ARG A 1 65  ? -18.01700 -26.69800 8.32400   1.000 41.92808  ? 65  ARG A NH2  1 
ATOM   998  H H    . ARG A 1 65  ? -21.49900 -28.41000 14.56400  1.000 55.64819  ? 65  ARG A H    1 
ATOM   999  H HA   . ARG A 1 65  ? -18.98800 -28.69000 13.54800  1.000 65.86819  ? 65  ARG A HA   1 
ATOM   1000 H HB2  . ARG A 1 65  ? -21.12300 -27.15200 12.51800  1.000 53.72819  ? 65  ARG A HB2  1 
ATOM   1001 H HB3  . ARG A 1 65  ? -19.64400 -27.04500 11.96200  1.000 53.72819  ? 65  ARG A HB3  1 
ATOM   1002 H HG2  . ARG A 1 65  ? -20.99800 -29.49600 11.80800  1.000 56.33819  ? 65  ARG A HG2  1 
ATOM   1003 H HG3  . ARG A 1 65  ? -21.21400 -28.39800 10.67800  1.000 56.33819  ? 65  ARG A HG3  1 
ATOM   1004 H HD2  . ARG A 1 65  ? -18.74900 -29.65100 11.28400  1.000 58.66819  ? 65  ARG A HD2  1 
ATOM   1005 H HD3  . ARG A 1 65  ? -19.57000 -29.86600 9.94600   1.000 58.66819  ? 65  ARG A HD3  1 
ATOM   1006 H HE   . ARG A 1 65  ? -18.00200 -27.71900 10.50600  1.000 47.99819  ? 65  ARG A HE   1 
ATOM   1007 H HH11 . ARG A 1 65  ? -19.98900 -29.04300 8.18500   1.000 53.14819  ? 65  ARG A HH11 1 
ATOM   1008 H HH12 . ARG A 1 65  ? -19.60000 -28.09200 7.11000   1.000 53.14819  ? 65  ARG A HH12 1 
ATOM   1009 H HH21 . ARG A 1 65  ? -17.48000 -26.28800 8.85700   1.000 54.57819  ? 65  ARG A HH21 1 
ATOM   1010 H HH22 . ARG A 1 65  ? -18.09500 -26.43700 7.50800   1.000 54.57819  ? 65  ARG A HH22 1 
ATOM   1011 N N    . THR A 1 66  ? -18.33900 -27.23600 15.48800  1.000 63.27460  ? 66  THR A N    1 
ATOM   1012 C CA   . THR A 1 66  ? -17.69200 -26.22300 16.31200  1.000 55.99346  ? 66  THR A CA   1 
ATOM   1013 C C    . THR A 1 66  ? -17.20800 -25.05400 15.46400  1.000 50.94136  ? 66  THR A C    1 
ATOM   1014 O O    . THR A 1 66  ? -17.22700 -23.90300 15.91200  1.000 50.62701  ? 66  THR A O    1 
ATOM   1015 C CB   . THR A 1 66  ? -16.50400 -26.82900 17.06100  1.000 63.82637  ? 66  THR A CB   1 
ATOM   1016 O OG1  . THR A 1 66  ? -15.58000 -27.38600 16.11300  1.000 77.90381  ? 66  THR A OG1  1 
ATOM   1017 C CG2  . THR A 1 66  ? -16.95400 -27.93700 18.01900  1.000 69.65674  ? 66  THR A CG2  1 
ATOM   1018 H H    . THR A 1 66  ? -18.04800 -28.03200 15.63400  1.000 82.70819  ? 66  THR A H    1 
ATOM   1019 H HA   . THR A 1 66  ? -18.32600 -25.88600 16.96500  1.000 72.11819  ? 66  THR A HA   1 
ATOM   1020 H HB   . THR A 1 66  ? -16.06000 -26.13800 17.57700  1.000 79.91819  ? 66  THR A HB   1 
ATOM   1021 H HG1  . THR A 1 66  ? -15.95500 -27.99100 15.66800  1.000 97.39819  ? 66  THR A HG1  1 
ATOM   1022 H HG21 . THR A 1 66  ? -16.19400 -28.26700 18.52400  1.000 86.48819  ? 66  THR A HG21 1 
ATOM   1023 H HG22 . THR A 1 66  ? -17.61600 -27.59100 18.63700  1.000 86.48819  ? 66  THR A HG22 1 
ATOM   1024 H HG23 . THR A 1 66  ? -17.34300 -28.67100 17.51900  1.000 86.48819  ? 66  THR A HG23 1 
ATOM   1025 N N    . ASP A 1 67  ? -16.80100 -25.34100 14.22300  1.000 63.03334  ? 67  ASP A N    1 
ATOM   1026 C CA   . ASP A 1 67  ? -16.04900 -24.37800 13.42700  1.000 54.08735  ? 67  ASP A CA   1 
ATOM   1027 C C    . ASP A 1 67  ? -16.92100 -23.30200 12.79100  1.000 52.71923  ? 67  ASP A C    1 
ATOM   1028 O O    . ASP A 1 67  ? -16.42700 -22.20600 12.51200  1.000 54.72521  ? 67  ASP A O    1 
ATOM   1029 C CB   . ASP A 1 67  ? -15.26700 -25.10900 12.33200  1.000 58.41863  ? 67  ASP A CB   1 
ATOM   1030 C CG   . ASP A 1 67  ? -16.17000 -25.87700 11.37600  1.000 47.16953  ? 67  ASP A CG   1 
ATOM   1031 O OD1  . ASP A 1 67  ? -17.08900 -26.59000 11.82600  1.000 48.23215  ? 67  ASP A OD1  1 
ATOM   1032 O OD2  . ASP A 1 67  ? -15.96200 -25.76200 10.15500  1.000 50.18371  ? 67  ASP A OD2  1 
ATOM   1033 H H    . ASP A 1 67  ? -16.94900 -26.08800 13.82400  1.000 74.98819  ? 67  ASP A H    1 
ATOM   1034 H HA   . ASP A 1 67  ? -15.40700 -23.93400 14.00300  1.000 63.83819  ? 67  ASP A HA   1 
ATOM   1035 H HB2  . ASP A 1 67  ? -14.76600 -24.46000 11.81500  1.000 69.69819  ? 67  ASP A HB2  1 
ATOM   1036 H HB3  . ASP A 1 67  ? -14.66100 -25.74300 12.74600  1.000 69.69819  ? 67  ASP A HB3  1 
ATOM   1037 N N    . VAL A 1 68  ? -18.17700 -23.57200 12.54900  1.000 59.14604  ? 68  VAL A N    1 
ATOM   1038 C CA   . VAL A 1 68  ? -19.03200 -22.61700 11.85200  1.000 55.55987  ? 68  VAL A CA   1 
ATOM   1039 C C    . VAL A 1 68  ? -19.60000 -21.60600 12.84100  1.000 56.80136  ? 68  VAL A C    1 
ATOM   1040 O O    . VAL A 1 68  ? -19.80400 -21.90100 14.02500  1.000 55.74641  ? 68  VAL A O    1 
ATOM   1041 C CB   . VAL A 1 68  ? -20.16700 -23.33900 11.09500  1.000 51.62552  ? 68  VAL A CB   1 
ATOM   1042 C CG1  . VAL A 1 68  ? -19.64100 -24.09200 9.87600   1.000 61.08192  ? 68  VAL A CG1  1 
ATOM   1043 C CG2  . VAL A 1 68  ? -20.90300 -24.28800 12.03200  1.000 56.46480  ? 68  VAL A CG2  1 
ATOM   1044 H H    . VAL A 1 68  ? -18.56400 -24.30200 12.78000  1.000 66.92819  ? 68  VAL A H    1 
ATOM   1045 H HA   . VAL A 1 68  ? -18.50100 -22.13300 11.20100  1.000 63.26819  ? 68  VAL A HA   1 
ATOM   1046 H HB   . VAL A 1 68  ? -20.80400 -22.67800 10.78300  1.000 60.39819  ? 68  VAL A HB   1 
ATOM   1047 H HG11 . VAL A 1 68  ? -20.37600 -24.56600 9.45700   1.000 72.60819  ? 68  VAL A HG11 1 
ATOM   1048 H HG12 . VAL A 1 68  ? -19.25900 -23.45500 9.25200   1.000 72.60819  ? 68  VAL A HG12 1 
ATOM   1049 H HG13 . VAL A 1 68  ? -18.96200 -24.72300 10.16400  1.000 72.60819  ? 68  VAL A HG13 1 
ATOM   1050 H HG21 . VAL A 1 68  ? -21.68300 -24.63900 11.57300  1.000 66.49819  ? 68  VAL A HG21 1 
ATOM   1051 H HG22 . VAL A 1 68  ? -20.31300 -25.01300 12.27500  1.000 66.49819  ? 68  VAL A HG22 1 
ATOM   1052 H HG23 . VAL A 1 68  ? -21.17900 -23.80300 12.82500  1.000 66.49819  ? 68  VAL A HG23 1 
ATOM   1053 N N    . THR A 1 69  ? -19.84900 -20.39300 12.34500  1.000 54.08775  ? 69  THR A N    1 
ATOM   1054 C CA   . THR A 1 69  ? -20.60100 -19.35900 13.04300  1.000 49.64386  ? 69  THR A CA   1 
ATOM   1055 C C    . THR A 1 69  ? -22.07200 -19.48800 12.65800  1.000 51.24467  ? 69  THR A C    1 
ATOM   1056 O O    . THR A 1 69  ? -22.40400 -19.97500 11.57500  1.000 52.33759  ? 69  THR A O    1 
ATOM   1057 C CB   . THR A 1 69  ? -20.07900 -17.95500 12.68900  1.000 57.82067  ? 69  THR A CB   1 
ATOM   1058 O OG1  . THR A 1 69  ? -20.72000 -17.46700 11.49900  1.000 71.57927  ? 69  THR A OG1  1 
ATOM   1059 C CG2  . THR A 1 69  ? -18.56700 -17.97400 12.47100  1.000 61.96251  ? 69  THR A CG2  1 
ATOM   1060 H H    . THR A 1 69  ? -19.58100 -20.14200 11.56800  1.000 62.65819  ? 69  THR A H    1 
ATOM   1061 H HA   . THR A 1 69  ? -20.51900 -19.48700 14.00100  1.000 56.38819  ? 69  THR A HA   1 
ATOM   1062 H HB   . THR A 1 69  ? -20.27000 -17.35100 13.42300  1.000 64.83819  ? 69  THR A HB   1 
ATOM   1063 H HG1  . THR A 1 69  ? -20.43100 -16.70100 11.31100  1.000 82.39819  ? 69  THR A HG1  1 
ATOM   1064 H HG21 . THR A 1 69  ? -18.22300 -17.06700 12.45900  1.000 68.79819  ? 69  THR A HG21 1 
ATOM   1065 H HG22 . THR A 1 69  ? -18.13600 -18.46500 13.18800  1.000 68.79819  ? 69  THR A HG22 1 
ATOM   1066 H HG23 . THR A 1 69  ? -18.35700 -18.40100 11.62600  1.000 68.79819  ? 69  THR A HG23 1 
ATOM   1067 N N    . GLY A 1 70  ? -22.95700 -19.07800 13.56800  1.000 49.37277  ? 70  GLY A N    1 
ATOM   1068 C CA   . GLY A 1 70  ? -24.37800 -19.08300 13.26000  1.000 45.91503  ? 70  GLY A CA   1 
ATOM   1069 C C    . GLY A 1 70  ? -24.73000 -18.03300 12.22300  1.000 38.22022  ? 70  GLY A C    1 
ATOM   1070 O O    . GLY A 1 70  ? -24.09100 -16.98900 12.11800  1.000 45.31084  ? 70  GLY A O    1 
ATOM   1071 H H    . GLY A 1 70  ? -22.76000 -18.79800 14.35700  1.000 62.20819  ? 70  GLY A H    1 
ATOM   1072 H HA2  . GLY A 1 70  ? -24.63400 -19.95400 12.91800  1.000 59.17819  ? 70  GLY A HA2  1 
ATOM   1073 H HA3  . GLY A 1 70  ? -24.88700 -18.90500 14.06600  1.000 59.17819  ? 70  GLY A HA3  1 
ATOM   1074 N N    . MET A 1 71  ? -25.74200 -18.32900 11.41200  1.000 46.23747  ? 71  MET A N    1 
ATOM   1075 C CA   . MET A 1 71  ? -26.15900 -17.43100 10.34500  1.000 46.68999  ? 71  MET A CA   1 
ATOM   1076 C C    . MET A 1 71  ? -27.61200 -17.02800 10.54900  1.000 44.55287  ? 71  MET A C    1 
ATOM   1077 O O    . MET A 1 71  ? -28.37400 -17.70400 11.24700  1.000 43.78694  ? 71  MET A O    1 
ATOM   1078 C CB   . MET A 1 71  ? -26.00600 -18.06900 8.95100   1.000 44.97593  ? 71  MET A CB   1 
ATOM   1079 C CG   . MET A 1 71  ? -24.60300 -18.03000 8.35200   1.000 50.85901  ? 71  MET A CG   1 
ATOM   1080 S SD   . MET A 1 71  ? -24.60800 -18.62000 6.63900   1.000 52.40681  ? 71  MET A SD   1 
ATOM   1081 C CE   . MET A 1 71  ? -25.79800 -17.53800 5.86200   1.000 57.47126  ? 71  MET A CE   1 
ATOM   1082 H H    . MET A 1 71  ? -26.20600 -19.05100 11.46100  1.000 55.49819  ? 71  MET A H    1 
ATOM   1083 H HA   . MET A 1 71  ? -25.60900 -16.63300 10.36600  1.000 56.24819  ? 71  MET A HA   1 
ATOM   1084 H HB2  . MET A 1 71  ? -26.27000 -19.00100 9.01000   1.000 55.57819  ? 71  MET A HB2  1 
ATOM   1085 H HB3  . MET A 1 71  ? -26.60200 -17.60300 8.34500   1.000 55.57819  ? 71  MET A HB3  1 
ATOM   1086 H HG2  . MET A 1 71  ? -24.28200 -17.11500 8.35500   1.000 62.23819  ? 71  MET A HG2  1 
ATOM   1087 H HG3  . MET A 1 71  ? -24.01100 -18.59100 8.87300   1.000 62.23819  ? 71  MET A HG3  1 
ATOM   1088 H HE1  . MET A 1 71  ? -25.69100 -17.59300 4.90000   1.000 71.36819  ? 71  MET A HE1  1 
ATOM   1089 H HE2  . MET A 1 71  ? -26.69200 -17.81800 6.11100   1.000 71.36819  ? 71  MET A HE2  1 
ATOM   1090 H HE3  . MET A 1 71  ? -25.63900 -16.62900 6.15900   1.000 71.36819  ? 71  MET A HE3  1 
ATOM   1091 N N    . ILE A 1 72  ? -27.98600 -15.90900 9.93100   1.000 55.95404  ? 72  ILE A N    1 
ATOM   1092 C CA   . ILE A 1 72  ? -29.35300 -15.40600 10.01300  1.000 47.22220  ? 72  ILE A CA   1 
ATOM   1093 C C    . ILE A 1 72  ? -30.23900 -16.23600 9.09700   1.000 46.18021  ? 72  ILE A C    1 
ATOM   1094 O O    . ILE A 1 72  ? -29.91600 -16.44400 7.92100   1.000 49.56658  ? 72  ILE A O    1 
ATOM   1095 C CB   . ILE A 1 72  ? -29.40900 -13.91700 9.63900   1.000 52.68679  ? 72  ILE A CB   1 
ATOM   1096 C CG1  . ILE A 1 72  ? -28.58100 -13.09400 10.62900  1.000 56.87307  ? 72  ILE A CG1  1 
ATOM   1097 C CG2  . ILE A 1 72  ? -30.85500 -13.41600 9.62900   1.000 59.40363  ? 72  ILE A CG2  1 
ATOM   1098 C CD1  . ILE A 1 72  ? -27.67500 -12.07300 9.97700   1.000 69.13594  ? 72  ILE A CD1  1 
ATOM   1099 H H    . ILE A 1 72  ? -27.46200 -15.42100 9.45500   1.000 62.80819  ? 72  ILE A H    1 
ATOM   1100 H HA   . ILE A 1 72  ? -29.67700 -15.50400 10.92200  1.000 52.26819  ? 72  ILE A HA   1 
ATOM   1101 H HB   . ILE A 1 72  ? -29.03500 -13.80500 8.75100   1.000 57.53819  ? 72  ILE A HB   1 
ATOM   1102 H HG12 . ILE A 1 72  ? -29.18600 -12.61600 11.21800  1.000 60.61819  ? 72  ILE A HG12 1 
ATOM   1103 H HG13 . ILE A 1 72  ? -28.02400 -13.69300 11.15000  1.000 60.61819  ? 72  ILE A HG13 1 
ATOM   1104 H HG21 . ILE A 1 72  ? -30.85200 -12.44600 9.61100   1.000 65.49819  ? 72  ILE A HG21 1 
ATOM   1105 H HG22 . ILE A 1 72  ? -31.29900 -13.75900 8.84000   1.000 65.49819  ? 72  ILE A HG22 1 
ATOM   1106 H HG23 . ILE A 1 72  ? -31.30500 -13.73100 10.42900  1.000 65.49819  ? 72  ILE A HG23 1 
ATOM   1107 H HD11 . ILE A 1 72  ? -27.18700 -11.59700 10.66800  1.000 74.20819  ? 72  ILE A HD11 1 
ATOM   1108 H HD12 . ILE A 1 72  ? -27.05400 -12.53200 9.38900   1.000 74.20819  ? 72  ILE A HD12 1 
ATOM   1109 H HD13 . ILE A 1 72  ? -28.21700 -11.45100 9.46600   1.000 74.20819  ? 72  ILE A HD13 1 
ATOM   1110 N N    . LEU A 1 73  ? -31.34800 -16.72800 9.64200   1.000 43.30785  ? 73  LEU A N    1 
ATOM   1111 C CA   . LEU A 1 73  ? -32.33600 -17.49900 8.89900   1.000 41.93688  ? 73  LEU A CA   1 
ATOM   1112 C C    . LEU A 1 73  ? -33.64400 -16.72900 8.91400   1.000 45.05201  ? 73  LEU A C    1 
ATOM   1113 O O    . LEU A 1 73  ? -34.17000 -16.41300 9.99100   1.000 38.81538  ? 73  LEU A O    1 
ATOM   1114 C CB   . LEU A 1 73  ? -32.53600 -18.88600 9.50600   1.000 41.63381  ? 73  LEU A CB   1 
ATOM   1115 C CG   . LEU A 1 73  ? -33.54400 -19.81600 8.83300   1.000 37.42542  ? 73  LEU A CG   1 
ATOM   1116 C CD1  . LEU A 1 73  ? -33.25700 -19.98800 7.36300   1.000 39.12931  ? 73  LEU A CD1  1 
ATOM   1117 C CD2  . LEU A 1 73  ? -33.48300 -21.15200 9.56400   1.000 41.44899  ? 73  LEU A CD2  1 
ATOM   1118 H H    . LEU A 1 73  ? -31.55500 -16.62300 10.47000  1.000 53.44819  ? 73  LEU A H    1 
ATOM   1119 H HA   . LEU A 1 73  ? -32.04600 -17.60100 7.98000   1.000 53.05819  ? 73  LEU A HA   1 
ATOM   1120 H HB2  . LEU A 1 73  ? -31.68000 -19.34200 9.49800   1.000 53.40819  ? 73  LEU A HB2  1 
ATOM   1121 H HB3  . LEU A 1 73  ? -32.82600 -18.77200 10.42500  1.000 53.40819  ? 73  LEU A HB3  1 
ATOM   1122 H HG   . LEU A 1 73  ? -34.43700 -19.45200 8.93200   1.000 49.42819  ? 73  LEU A HG   1 
ATOM   1123 H HD11 . LEU A 1 73  ? -33.86800 -20.64800 6.99900   1.000 52.27819  ? 73  LEU A HD11 1 
ATOM   1124 H HD12 . LEU A 1 73  ? -33.38500 -19.13800 6.91400   1.000 52.27819  ? 73  LEU A HD12 1 
ATOM   1125 H HD13 . LEU A 1 73  ? -32.34200 -20.29000 7.25300   1.000 52.27819  ? 73  LEU A HD13 1 
ATOM   1126 H HD21 . LEU A 1 73  ? -32.58700 -21.51400 9.48500   1.000 54.59819  ? 73  LEU A HD21 1 
ATOM   1127 H HD22 . LEU A 1 73  ? -33.70200 -21.01100 10.49800  1.000 54.59819  ? 73  LEU A HD22 1 
ATOM   1128 H HD23 . LEU A 1 73  ? -34.12300 -21.76100 9.16200   1.000 54.59819  ? 73  LEU A HD23 1 
ATOM   1129 N N    . GLU A 1 74  ? -34.17500 -16.44900 7.72400   1.000 43.65140  ? 74  GLU A N    1 
ATOM   1130 C CA   . GLU A 1 74  ? -35.40400 -15.69200 7.57200   1.000 44.12225  ? 74  GLU A CA   1 
ATOM   1131 C C    . GLU A 1 74  ? -36.30300 -16.36900 6.54800   1.000 46.89928  ? 74  GLU A C    1 
ATOM   1132 O O    . GLU A 1 74  ? -35.86300 -17.17700 5.72800   1.000 44.56845  ? 74  GLU A O    1 
ATOM   1133 C CB   . GLU A 1 74  ? -35.10700 -14.23400 7.16900   1.000 45.19752  ? 74  GLU A CB   1 
ATOM   1134 C CG   . GLU A 1 74  ? -34.06900 -13.54500 8.06600   1.000 45.17566  ? 74  GLU A CG   1 
ATOM   1135 C CD   . GLU A 1 74  ? -34.03700 -12.02900 7.92600   1.000 52.61431  ? 74  GLU A CD   1 
ATOM   1136 O OE1  . GLU A 1 74  ? -34.12600 -11.51600 6.78600   1.000 62.97107  ? 74  GLU A OE1  1 
ATOM   1137 O OE2  . GLU A 1 74  ? -33.91900 -11.34900 8.97000   1.000 51.50879  ? 74  GLU A OE2  1 
ATOM   1138 H H    . GLU A 1 74  ? -33.82900 -16.69500 6.97600   1.000 53.45819  ? 74  GLU A H    1 
ATOM   1139 H HA   . GLU A 1 74  ? -35.87500 -15.67800 8.42000   1.000 53.47819  ? 74  GLU A HA   1 
ATOM   1140 H HB2  . GLU A 1 74  ? -34.76800 -14.22300 6.26000   1.000 53.59819  ? 74  GLU A HB2  1 
ATOM   1141 H HB3  . GLU A 1 74  ? -35.92900 -13.72200 7.21900   1.000 53.59819  ? 74  GLU A HB3  1 
ATOM   1142 H HG2  . GLU A 1 74  ? -34.26500 -13.75500 8.99200   1.000 52.38819  ? 74  GLU A HG2  1 
ATOM   1143 H HG3  . GLU A 1 74  ? -33.19200 -13.88200 7.83000   1.000 52.38819  ? 74  GLU A HG3  1 
ATOM   1144 N N    . GLU A 1 75  ? -37.58400 -16.04900 6.64400   1.000 41.78988  ? 75  GLU A N    1 
ATOM   1145 C CA   . GLU A 1 75  ? -38.60800 -16.56200 5.74300   1.000 41.92791  ? 75  GLU A CA   1 
ATOM   1146 C C    . GLU A 1 75  ? -38.51900 -15.82100 4.41600   1.000 39.07954  ? 75  GLU A C    1 
ATOM   1147 O O    . GLU A 1 75  ? -39.19100 -14.80700 4.20500   1.000 46.61912  ? 75  GLU A O    1 
ATOM   1148 C CB   . GLU A 1 75  ? -39.97200 -16.39700 6.39000   1.000 48.07175  ? 75  GLU A CB   1 
ATOM   1149 C CG   . GLU A 1 75  ? -41.12700 -16.83500 5.55200   1.000 62.31873  ? 75  GLU A CG   1 
ATOM   1150 C CD   . GLU A 1 75  ? -42.44000 -16.52200 6.22600   1.000 87.62528  ? 75  GLU A CD   1 
ATOM   1151 O OE1  . GLU A 1 75  ? -42.44200 -16.35200 7.46200   1.000 80.08159  ? 75  GLU A OE1  1 
ATOM   1152 O OE2  . GLU A 1 75  ? -43.46400 -16.43100 5.52500   1.000 99.54087  ? 75  GLU A OE2  1 
ATOM   1153 H H    . GLU A 1 75  ? -37.89600 -15.51800 7.24400   1.000 55.34819  ? 75  GLU A H    1 
ATOM   1154 H HA   . GLU A 1 75  ? -38.45500 -17.50600 5.58100   1.000 56.05819  ? 75  GLU A HA   1 
ATOM   1155 H HB2  . GLU A 1 75  ? -39.99000 -16.91800 7.20800   1.000 62.79819  ? 75  GLU A HB2  1 
ATOM   1156 H HB3  . GLU A 1 75  ? -40.10200 -15.45900 6.60000   1.000 62.79819  ? 75  GLU A HB3  1 
ATOM   1157 H HG2  . GLU A 1 75  ? -41.10800 -16.37000 4.70100   1.000 80.14819  ? 75  GLU A HG2  1 
ATOM   1158 H HG3  . GLU A 1 75  ? -41.07700 -17.79400 5.41300   1.000 80.14819  ? 75  GLU A HG3  1 
ATOM   1159 N N    . GLY A 1 76  ? -37.69400 -16.33400 3.51300   1.000 46.03184  ? 76  GLY A N    1 
ATOM   1160 C CA   . GLY A 1 76  ? -37.51700 -15.71900 2.21100   1.000 42.58643  ? 76  GLY A CA   1 
ATOM   1161 C C    . GLY A 1 76  ? -36.80700 -14.37900 2.25500   1.000 43.53277  ? 76  GLY A C    1 
ATOM   1162 O O    . GLY A 1 76  ? -36.38900 -13.93200 3.32700   1.000 44.11365  ? 76  GLY A O    1 
ATOM   1163 H H    . GLY A 1 76  ? -37.22300 -17.04300 3.63300   1.000 57.40819  ? 76  GLY A H    1 
ATOM   1164 H HA2  . GLY A 1 76  ? -37.01900 -16.31700 1.63400   1.000 52.86819  ? 76  GLY A HA2  1 
ATOM   1165 H HA3  . GLY A 1 76  ? -38.38800 -15.58500 1.81100   1.000 52.86819  ? 76  GLY A HA3  1 
ATOM   1166 N N    . ALA A 1 77  ? -36.65200 -13.73500 1.09300   1.000 43.49991  ? 77  ALA A N    1 
ATOM   1167 C CA   . ALA A 1 77  ? -36.03500 -12.41500 0.99200   1.000 44.63784  ? 77  ALA A CA   1 
ATOM   1168 C C    . ALA A 1 77  ? -37.06300 -11.43800 0.43400   1.000 45.28540  ? 77  ALA A C    1 
ATOM   1169 O O    . ALA A 1 77  ? -38.11000 -11.87500 -0.05600  1.000 47.37877  ? 77  ALA A O    1 
ATOM   1170 C CB   . ALA A 1 77  ? -34.79800 -12.45300 0.09300   1.000 53.00341  ? 77  ALA A CB   1 
ATOM   1171 H H    . ALA A 1 77  ? -36.90300 -14.05300 0.33400   1.000 51.93819  ? 77  ALA A H    1 
ATOM   1172 H HA   . ALA A 1 77  ? -35.76600 -12.11300 1.87300   1.000 52.00819  ? 77  ALA A HA   1 
ATOM   1173 H HB1  . ALA A 1 77  ? -34.15200 -13.07000 0.46700   1.000 61.89819  ? 77  ALA A HB1  1 
ATOM   1174 H HB2  . ALA A 1 77  ? -35.06200 -12.74700 -0.79300  1.000 61.89819  ? 77  ALA A HB2  1 
ATOM   1175 H HB3  . ALA A 1 77  ? -34.41600 -11.56300 0.04600   1.000 61.89819  ? 77  ALA A HB3  1 
ATOM   1176 N N    . PRO A 1 78  ? -36.82700 -10.12300 0.50500   1.000 48.48817  ? 78  PRO A N    1 
ATOM   1177 C CA   . PRO A 1 78  ? -37.78600 -9.18600  -0.10300  1.000 51.09709  ? 78  PRO A CA   1 
ATOM   1178 C C    . PRO A 1 78  ? -37.91400 -9.42300  -1.60200  1.000 47.54334  ? 78  PRO A C    1 
ATOM   1179 O O    . PRO A 1 78  ? -36.93900 -9.73800  -2.28500  1.000 50.00875  ? 78  PRO A O    1 
ATOM   1180 C CB   . PRO A 1 78  ? -37.19100 -7.80400  0.21100   1.000 46.29293  ? 78  PRO A CB   1 
ATOM   1181 C CG   . PRO A 1 78  ? -36.39000 -8.00900  1.48700   1.000 42.12701  ? 78  PRO A CG   1 
ATOM   1182 C CD   . PRO A 1 78  ? -35.83600 -9.43500  1.35800   1.000 55.25891  ? 78  PRO A CD   1 
ATOM   1183 H HA   . PRO A 1 78  ? -38.65700 -9.26900  0.31600   1.000 59.28819  ? 78  PRO A HA   1 
ATOM   1184 H HB2  . PRO A 1 78  ? -36.61400 -7.52200  -0.51600  1.000 51.81819  ? 78  PRO A HB2  1 
ATOM   1185 H HB3  . PRO A 1 78  ? -37.90600 -7.16400  0.35200   1.000 51.81819  ? 78  PRO A HB3  1 
ATOM   1186 H HG2  . PRO A 1 78  ? -35.67000 -7.36100  1.53200   1.000 47.16819  ? 78  PRO A HG2  1 
ATOM   1187 H HG3  . PRO A 1 78  ? -36.97300 -7.93300  2.25800   1.000 47.16819  ? 78  PRO A HG3  1 
ATOM   1188 H HD2  . PRO A 1 78  ? -34.96900 -9.42200  0.92400   1.000 64.72819  ? 78  PRO A HD2  1 
ATOM   1189 H HD3  . PRO A 1 78  ? -35.79000 -9.85700  2.23000   1.000 64.72819  ? 78  PRO A HD3  1 
ATOM   1190 N N    . GLU A 1 79  ? -39.14400 -9.30700  -2.10000  1.000 50.31662  ? 79  GLU A N    1 
ATOM   1191 C CA   . GLU A 1 79  ? -39.41800 -9.40700  -3.52900  1.000 49.25772  ? 79  GLU A CA   1 
ATOM   1192 C C    . GLU A 1 79  ? -38.44700 -8.55300  -4.33200  1.000 46.41301  ? 79  GLU A C    1 
ATOM   1193 O O    . GLU A 1 79  ? -38.29900 -7.35700  -4.07000  1.000 53.20177  ? 79  GLU A O    1 
ATOM   1194 C CB   . GLU A 1 79  ? -40.85900 -8.96000  -3.79700  1.000 46.61554  ? 79  GLU A CB   1 
ATOM   1195 C CG   . GLU A 1 79  ? -41.93900 -9.90000  -3.25100  1.000 51.08596  ? 79  GLU A CG   1 
ATOM   1196 C CD   . GLU A 1 79  ? -42.34100 -9.60800  -1.81500  1.000 46.53735  ? 79  GLU A CD   1 
ATOM   1197 O OE1  . GLU A 1 79  ? -41.78500 -8.67200  -1.19500  1.000 46.97935  ? 79  GLU A OE1  1 
ATOM   1198 O OE2  . GLU A 1 79  ? -43.22900 -10.33200 -1.31100  1.000 41.64803  ? 79  GLU A OE2  1 
ATOM   1199 H H    . GLU A 1 79  ? -39.84400 -9.16700  -1.62200  1.000 60.90819  ? 79  GLU A H    1 
ATOM   1200 H HA   . GLU A 1 79  ? -39.32400 -10.33000 -3.81300  1.000 59.08819  ? 79  GLU A HA   1 
ATOM   1201 H HB2  . GLU A 1 79  ? -40.99300 -8.08800  -3.39400  1.000 55.03819  ? 79  GLU A HB2  1 
ATOM   1202 H HB3  . GLU A 1 79  ? -40.98700 -8.89600  -4.75600  1.000 55.03819  ? 79  GLU A HB3  1 
ATOM   1203 H HG2  . GLU A 1 79  ? -42.73200 -9.81800  -3.80300  1.000 61.47819  ? 79  GLU A HG2  1 
ATOM   1204 H HG3  . GLU A 1 79  ? -41.60700 -10.81100 -3.28600  1.000 61.47819  ? 79  GLU A HG3  1 
ATOM   1205 N N    . GLY A 1 80  ? -37.79400 -9.16600  -5.32000  1.000 44.97071  ? 80  GLY A N    1 
ATOM   1206 C CA   . GLY A 1 80  ? -36.82900 -8.47800  -6.14900  1.000 41.50923  ? 80  GLY A CA   1 
ATOM   1207 C C    . GLY A 1 80  ? -35.38800 -8.65500  -5.72800  1.000 43.14669  ? 80  GLY A C    1 
ATOM   1208 O O    . GLY A 1 80  ? -34.49000 -8.20600  -6.45200  1.000 48.77154  ? 80  GLY A O    1 
ATOM   1209 H H    . GLY A 1 80  ? -37.90000 -9.99400  -5.52700  1.000 54.61819  ? 80  GLY A H    1 
ATOM   1210 H HA2  . GLY A 1 80  ? -36.91400 -8.79800  -7.06100  1.000 49.05819  ? 80  GLY A HA2  1 
ATOM   1211 H HA3  . GLY A 1 80  ? -37.02700 -7.52900  -6.14500  1.000 49.05819  ? 80  GLY A HA3  1 
ATOM   1212 N N    . THR A 1 81  ? -35.13800 -9.29800  -4.58800  1.000 46.92178  ? 81  THR A N    1 
ATOM   1213 C CA   . THR A 1 81  ? -33.77000 -9.52500  -4.13800  1.000 44.40864  ? 81  THR A CA   1 
ATOM   1214 C C    . THR A 1 81  ? -33.08600 -10.57500 -5.01000  1.000 42.07673  ? 81  THR A C    1 
ATOM   1215 O O    . THR A 1 81  ? -33.66100 -11.62500 -5.30800  1.000 45.18553  ? 81  THR A O    1 
ATOM   1216 C CB   . THR A 1 81  ? -33.75500 -9.97100  -2.67400  1.000 43.28833  ? 81  THR A CB   1 
ATOM   1217 O OG1  . THR A 1 81  ? -34.07400 -8.86000  -1.82500  1.000 39.24937  ? 81  THR A OG1  1 
ATOM   1218 C CG2  . THR A 1 81  ? -32.38100 -10.52900 -2.30500  1.000 41.81203  ? 81  THR A CG2  1 
ATOM   1219 H H    . THR A 1 81  ? -35.74100 -9.61100  -4.06000  1.000 54.79819  ? 81  THR A H    1 
ATOM   1220 H HA   . THR A 1 81  ? -33.26900 -8.69800  -4.20900  1.000 52.12819  ? 81  THR A HA   1 
ATOM   1221 H HB   . THR A 1 81  ? -34.41300 -10.67200 -2.54600  1.000 52.04819  ? 81  THR A HB   1 
ATOM   1222 H HG1  . THR A 1 81  ? -34.05800 -9.10000  -1.02000  1.000 46.20819  ? 81  THR A HG1  1 
ATOM   1223 H HG21 . THR A 1 81  ? -32.27200 -10.51800 -1.34200  1.000 50.82819  ? 81  THR A HG21 1 
ATOM   1224 H HG22 . THR A 1 81  ? -32.29400 -11.44300 -2.61900  1.000 50.82819  ? 81  THR A HG22 1 
ATOM   1225 H HG23 . THR A 1 81  ? -31.68300 -9.98600  -2.70400  1.000 50.82819  ? 81  THR A HG23 1 
ATOM   1226 N N    . VAL A 1 82  ? -31.84400 -10.31100 -5.40400  1.000 40.28844  ? 82  VAL A N    1 
ATOM   1227 C CA   . VAL A 1 82  ? -31.07300 -11.27700 -6.17900  1.000 36.75695  ? 82  VAL A CA   1 
ATOM   1228 C C    . VAL A 1 82  ? -30.32500 -12.16000 -5.18300  1.000 43.97911  ? 82  VAL A C    1 
ATOM   1229 O O    . VAL A 1 82  ? -29.24700 -11.80900 -4.70500  1.000 40.17782  ? 82  VAL A O    1 
ATOM   1230 C CB   . VAL A 1 82  ? -30.13000 -10.59100 -7.16900  1.000 36.71345  ? 82  VAL A CB   1 
ATOM   1231 C CG1  . VAL A 1 82  ? -29.20100 -11.60400 -7.83400  1.000 49.25339  ? 82  VAL A CG1  1 
ATOM   1232 C CG2  . VAL A 1 82  ? -30.94000 -9.85200  -8.24000  1.000 39.76943  ? 82  VAL A CG2  1 
ATOM   1233 H H    . VAL A 1 82  ? -31.42500 -9.57900  -5.23500  1.000 53.47819  ? 82  VAL A H    1 
ATOM   1234 H HA   . VAL A 1 82  ? -31.68000 -11.84000 -6.68500  1.000 49.56819  ? 82  VAL A HA   1 
ATOM   1235 H HB   . VAL A 1 82  ? -29.58500 -9.94200  -6.69700  1.000 47.26819  ? 82  VAL A HB   1 
ATOM   1236 H HG11 . VAL A 1 82  ? -28.77100 -11.18300 -8.59500  1.000 62.92819  ? 82  VAL A HG11 1 
ATOM   1237 H HG12 . VAL A 1 82  ? -28.53100 -11.89000 -7.19400  1.000 62.92819  ? 82  VAL A HG12 1 
ATOM   1238 H HG13 . VAL A 1 82  ? -29.72500 -12.36500 -8.13100  1.000 62.92819  ? 82  VAL A HG13 1 
ATOM   1239 H HG21 . VAL A 1 82  ? -30.32800 -9.42500  -8.86000  1.000 49.37819  ? 82  VAL A HG21 1 
ATOM   1240 H HG22 . VAL A 1 82  ? -31.49700 -10.49100 -8.71200  1.000 49.37819  ? 82  VAL A HG22 1 
ATOM   1241 H HG23 . VAL A 1 82  ? -31.49600 -9.18300  -7.81000  1.000 49.37819  ? 82  VAL A HG23 1 
ATOM   1242 N N    . ALA A 1 83  ? -30.89600 -13.32000 -4.86700  1.000 53.63978  ? 83  ALA A N    1 
ATOM   1243 C CA   . ALA A 1 83  ? -30.22000 -14.25900 -3.98500  1.000 43.44367  ? 83  ALA A CA   1 
ATOM   1244 C C    . ALA A 1 83  ? -29.22500 -15.10400 -4.77900  1.000 43.18003  ? 83  ALA A C    1 
ATOM   1245 O O    . ALA A 1 83  ? -29.18700 -15.07100 -6.01000  1.000 41.68672  ? 83  ALA A O    1 
ATOM   1246 C CB   . ALA A 1 83  ? -31.23300 -15.15800 -3.28100  1.000 46.23236  ? 83  ALA A CB   1 
ATOM   1247 H H    . ALA A 1 83  ? -31.66500 -13.58300 -5.14800  1.000 63.70819  ? 83  ALA A H    1 
ATOM   1248 H HA   . ALA A 1 83  ? -29.72900 -13.76800 -3.30800  1.000 52.74819  ? 83  ALA A HA   1 
ATOM   1249 H HB1  . ALA A 1 83  ? -30.75900 -15.77300 -2.70000  1.000 57.55819  ? 83  ALA A HB1  1 
ATOM   1250 H HB2  . ALA A 1 83  ? -31.83500 -14.60600 -2.75800  1.000 57.55819  ? 83  ALA A HB2  1 
ATOM   1251 H HB3  . ALA A 1 83  ? -31.73300 -15.65300 -3.94900  1.000 57.55819  ? 83  ALA A HB3  1 
ATOM   1252 N N    . THR A 1 84  ? -28.40800 -15.87300 -4.05900  1.000 54.61839  ? 84  THR A N    1 
ATOM   1253 C CA   . THR A 1 84  ? -27.48800 -16.83400 -4.66000  1.000 44.72809  ? 84  THR A CA   1 
ATOM   1254 C C    . THR A 1 84  ? -27.91100 -18.23000 -4.22900  1.000 41.56298  ? 84  THR A C    1 
ATOM   1255 O O    . THR A 1 84  ? -28.16900 -18.45400 -3.04400  1.000 41.09849  ? 84  THR A O    1 
ATOM   1256 C CB   . THR A 1 84  ? -26.04000 -16.56100 -4.23400  1.000 41.52960  ? 84  THR A CB   1 
ATOM   1257 O OG1  . THR A 1 84  ? -25.69800 -15.19800 -4.52000  1.000 49.75924  ? 84  THR A OG1  1 
ATOM   1258 C CG2  . THR A 1 84  ? -25.06400 -17.46300 -4.98200  1.000 43.45845  ? 84  THR A CG2  1 
ATOM   1259 H H    . THR A 1 84  ? -28.36900 -15.85400 -3.20000  1.000 63.27819  ? 84  THR A H    1 
ATOM   1260 H HA   . THR A 1 84  ? -27.54100 -16.77700 -5.62600  1.000 51.46819  ? 84  THR A HA   1 
ATOM   1261 H HB   . THR A 1 84  ? -25.94500 -16.72600 -3.28300  1.000 47.05819  ? 84  THR A HB   1 
ATOM   1262 H HG1  . THR A 1 84  ? -24.90500 -15.04600 -4.28800  1.000 55.37819  ? 84  THR A HG1  1 
ATOM   1263 H HG21 . THR A 1 84  ? -24.16900 -17.34900 -4.62600  1.000 49.11819  ? 84  THR A HG21 1 
ATOM   1264 H HG22 . THR A 1 84  ? -25.32500 -18.39200 -4.88600  1.000 49.11819  ? 84  THR A HG22 1 
ATOM   1265 H HG23 . THR A 1 84  ? -25.06000 -17.23500 -5.92500  1.000 49.11819  ? 84  THR A HG23 1 
ATOM   1266 N N    . LEU A 1 85  ? -28.02400 -19.15000 -5.19700  1.000 43.97626  ? 85  LEU A N    1 
ATOM   1267 C CA   . LEU A 1 85  ? -28.36800 -20.55500 -4.95800  1.000 42.83964  ? 85  LEU A CA   1 
ATOM   1268 C C    . LEU A 1 85  ? -27.05800 -21.33600 -4.97000  1.000 46.72430  ? 85  LEU A C    1 
ATOM   1269 O O    . LEU A 1 85  ? -26.50300 -21.63100 -6.03400  1.000 43.02531  ? 85  LEU A O    1 
ATOM   1270 C CB   . LEU A 1 85  ? -29.34200 -21.07200 -6.01100  1.000 41.07528  ? 85  LEU A CB   1 
ATOM   1271 C CG   . LEU A 1 85  ? -29.87900 -22.49900 -5.88300  1.000 38.88284  ? 85  LEU A CG   1 
ATOM   1272 C CD1  . LEU A 1 85  ? -30.40500 -22.83800 -4.50700  1.000 45.38590  ? 85  LEU A CD1  1 
ATOM   1273 C CD2  . LEU A 1 85  ? -30.98600 -22.67300 -6.92300  1.000 43.13025  ? 85  LEU A CD2  1 
ATOM   1274 H H    . LEU A 1 85  ? -27.90100 -18.97400 -6.03000  1.000 50.38819  ? 85  LEU A H    1 
ATOM   1275 H HA   . LEU A 1 85  ? -28.77600 -20.64600 -4.08300  1.000 50.09819  ? 85  LEU A HA   1 
ATOM   1276 H HB2  . LEU A 1 85  ? -30.11200 -20.48300 -6.01400  1.000 47.67819  ? 85  LEU A HB2  1 
ATOM   1277 H HB3  . LEU A 1 85  ? -28.90100 -21.01700 -6.87200  1.000 47.67819  ? 85  LEU A HB3  1 
ATOM   1278 H HG   . LEU A 1 85  ? -29.16900 -23.12100 -6.09500  1.000 45.85819  ? 85  LEU A HG   1 
ATOM   1279 H HD11 . LEU A 1 85  ? -31.23200 -23.32200 -4.61300  1.000 54.92819  ? 85  LEU A HD11 1 
ATOM   1280 H HD12 . LEU A 1 85  ? -29.75300 -23.38600 -4.04300  1.000 54.92819  ? 85  LEU A HD12 1 
ATOM   1281 H HD13 . LEU A 1 85  ? -30.56200 -22.01700 -4.01600  1.000 54.92819  ? 85  LEU A HD13 1 
ATOM   1282 H HD21 . LEU A 1 85  ? -31.34500 -23.57200 -6.85700  1.000 50.26819  ? 85  LEU A HD21 1 
ATOM   1283 H HD22 . LEU A 1 85  ? -31.68500 -22.02400 -6.75300  1.000 50.26819  ? 85  LEU A HD22 1 
ATOM   1284 H HD23 . LEU A 1 85  ? -30.61200 -22.53100 -7.80700  1.000 50.26819  ? 85  LEU A HD23 1 
ATOM   1285 N N    . LEU A 1 86  ? -26.55400 -21.64800 -3.78200  1.000 44.29926  ? 86  LEU A N    1 
ATOM   1286 C CA   . LEU A 1 86  ? -25.26600 -22.31600 -3.64100  1.000 40.76051  ? 86  LEU A CA   1 
ATOM   1287 C C    . LEU A 1 86  ? -25.43900 -23.80000 -3.95000  1.000 38.67942  ? 86  LEU A C    1 
ATOM   1288 O O    . LEU A 1 86  ? -25.64300 -24.62300 -3.05900  1.000 37.98749  ? 86  LEU A O    1 
ATOM   1289 C CB   . LEU A 1 86  ? -24.72500 -22.09500 -2.23600  1.000 42.64924  ? 86  LEU A CB   1 
ATOM   1290 C CG   . LEU A 1 86  ? -24.49900 -20.65300 -1.77600  1.000 42.75613  ? 86  LEU A CG   1 
ATOM   1291 C CD1  . LEU A 1 86  ? -23.80200 -20.68900 -0.41200  1.000 49.37462  ? 86  LEU A CD1  1 
ATOM   1292 C CD2  . LEU A 1 86  ? -23.69500 -19.86200 -2.78000  1.000 57.32195  ? 86  LEU A CD2  1 
ATOM   1293 H H    . LEU A 1 86  ? -26.94300 -21.48100 -3.03300  1.000 53.35819  ? 86  LEU A H    1 
ATOM   1294 H HA   . LEU A 1 86  ? -24.63600 -21.94400 -4.27800  1.000 48.99819  ? 86  LEU A HA   1 
ATOM   1295 H HB2  . LEU A 1 86  ? -25.34700 -22.49700 -1.61000  1.000 51.68819  ? 86  LEU A HB2  1 
ATOM   1296 H HB3  . LEU A 1 86  ? -23.87100 -22.55000 -2.17000  1.000 51.68819  ? 86  LEU A HB3  1 
ATOM   1297 H HG   . LEU A 1 86  ? -25.35800 -20.21600 -1.66500  1.000 51.13819  ? 86  LEU A HG   1 
ATOM   1298 H HD11 . LEU A 1 86  ? -23.59600 -19.78100 -0.14000  1.000 59.24819  ? 86  LEU A HD11 1 
ATOM   1299 H HD12 . LEU A 1 86  ? -24.39500 -21.10300 0.23500   1.000 59.24819  ? 86  LEU A HD12 1 
ATOM   1300 H HD13 . LEU A 1 86  ? -22.98400 -21.20400 -0.48900  1.000 59.24819  ? 86  LEU A HD13 1 
ATOM   1301 H HD21 . LEU A 1 86  ? -23.54400 -18.97000 -2.43000  1.000 67.21819  ? 86  LEU A HD21 1 
ATOM   1302 H HD22 . LEU A 1 86  ? -22.84600 -20.30800 -2.92500  1.000 67.21819  ? 86  LEU A HD22 1 
ATOM   1303 H HD23 . LEU A 1 86  ? -24.18800 -19.81200 -3.61300  1.000 67.21819  ? 86  LEU A HD23 1 
ATOM   1304 N N    . ILE A 1 87  ? -25.36100 -24.16000 -5.22600  1.000 45.99724  ? 87  ILE A N    1 
ATOM   1305 C CA   . ILE A 1 87  ? -25.48900 -25.55800 -5.62400  1.000 46.22950  ? 87  ILE A CA   1 
ATOM   1306 C C    . ILE A 1 87  ? -24.11000 -26.21100 -5.60600  1.000 41.78899  ? 87  ILE A C    1 
ATOM   1307 O O    . ILE A 1 87  ? -23.18700 -25.77400 -6.30000  1.000 46.72417  ? 87  ILE A O    1 
ATOM   1308 C CB   . ILE A 1 87  ? -26.16000 -25.69800 -7.00100  1.000 41.30651  ? 87  ILE A CB   1 
ATOM   1309 C CG1  . ILE A 1 87  ? -27.67900 -25.52800 -6.85300  1.000 43.56302  ? 87  ILE A CG1  1 
ATOM   1310 C CG2  . ILE A 1 87  ? -25.82300 -27.04400 -7.60800  1.000 46.50680  ? 87  ILE A CG2  1 
ATOM   1311 C CD1  . ILE A 1 87  ? -28.42100 -25.22400 -8.15400  1.000 64.68547  ? 87  ILE A CD1  1 
ATOM   1312 H H    . ILE A 1 87  ? -25.23500 -23.61600 -5.88000  1.000 53.31819  ? 87  ILE A H    1 
ATOM   1313 H HA   . ILE A 1 87  ? -26.04500 -26.02000 -4.97800  1.000 53.69819  ? 87  ILE A HA   1 
ATOM   1314 H HB   . ILE A 1 87  ? -25.82300 -25.00000 -7.58400  1.000 46.81819  ? 87  ILE A HB   1 
ATOM   1315 H HG12 . ILE A 1 87  ? -28.04700 -26.35000 -6.49200  1.000 50.08819  ? 87  ILE A HG12 1 
ATOM   1316 H HG13 . ILE A 1 87  ? -27.84600 -24.80000 -6.23700  1.000 50.08819  ? 87  ILE A HG13 1 
ATOM   1317 H HG21 . ILE A 1 87  ? -26.45900 -27.23400 -8.31500  1.000 52.51819  ? 87  ILE A HG21 1 
ATOM   1318 H HG22 . ILE A 1 87  ? -24.92600 -27.01600 -7.97600  1.000 52.51819  ? 87  ILE A HG22 1 
ATOM   1319 H HG23 . ILE A 1 87  ? -25.88400 -27.72800 -6.92200  1.000 52.51819  ? 87  ILE A HG23 1 
ATOM   1320 H HD11 . ILE A 1 87  ? -29.27100 -24.81300 -7.93700  1.000 74.25819  ? 87  ILE A HD11 1 
ATOM   1321 H HD12 . ILE A 1 87  ? -27.88600 -24.61600 -8.68700  1.000 74.25819  ? 87  ILE A HD12 1 
ATOM   1322 H HD13 . ILE A 1 87  ? -28.56300 -26.05200 -8.63900  1.000 74.25819  ? 87  ILE A HD13 1 
ATOM   1323 N N    . LYS A 1 88  ? -23.97000 -27.24400 -4.78400  1.000 38.20056  ? 88  LYS A N    1 
ATOM   1324 C CA   . LYS A 1 88  ? -22.85000 -28.16800 -4.85500  1.000 38.14678  ? 88  LYS A CA   1 
ATOM   1325 C C    . LYS A 1 88  ? -23.26900 -29.36300 -5.70000  1.000 41.06461  ? 88  LYS A C    1 
ATOM   1326 O O    . LYS A 1 88  ? -24.39000 -29.86600 -5.56400  1.000 43.75637  ? 88  LYS A O    1 
ATOM   1327 C CB   . LYS A 1 88  ? -22.43900 -28.64100 -3.45900  1.000 44.19777  ? 88  LYS A CB   1 
ATOM   1328 C CG   . LYS A 1 88  ? -21.00800 -29.14700 -3.34900  1.000 48.56549  ? 88  LYS A CG   1 
ATOM   1329 C CD   . LYS A 1 88  ? -20.59700 -29.36800 -1.90700  1.000 50.09671  ? 88  LYS A CD   1 
ATOM   1330 C CE   . LYS A 1 88  ? -20.33800 -28.03500 -1.24500  1.000 48.77683  ? 88  LYS A CE   1 
ATOM   1331 N NZ   . LYS A 1 88  ? -19.86000 -28.20600 0.14000   1.000 50.29850  ? 88  LYS A NZ   1 
ATOM   1332 H H    . LYS A 1 88  ? -24.52900 -27.43400 -4.15900  1.000 46.64819  ? 88  LYS A H    1 
ATOM   1333 H HA   . LYS A 1 88  ? -22.09000 -27.73600 -5.27600  1.000 46.10819  ? 88  LYS A HA   1 
ATOM   1334 H HB2  . LYS A 1 88  ? -22.54300 -27.89900 -2.84400  1.000 54.20819  ? 88  LYS A HB2  1 
ATOM   1335 H HB3  . LYS A 1 88  ? -23.02600 -29.36600 -3.19500  1.000 54.20819  ? 88  LYS A HB3  1 
ATOM   1336 H HG2  . LYS A 1 88  ? -20.93200 -29.99200 -3.81800  1.000 58.78819  ? 88  LYS A HG2  1 
ATOM   1337 H HG3  . LYS A 1 88  ? -20.40700 -28.49300 -3.73900  1.000 58.78819  ? 88  LYS A HG3  1 
ATOM   1338 H HD2  . LYS A 1 88  ? -21.31100 -29.81700 -1.42900  1.000 61.24819  ? 88  LYS A HD2  1 
ATOM   1339 H HD3  . LYS A 1 88  ? -19.78200 -29.89300 -1.87700  1.000 61.24819  ? 88  LYS A HD3  1 
ATOM   1340 H HE2  . LYS A 1 88  ? -19.65800 -27.55600 -1.74400  1.000 59.70819  ? 88  LYS A HE2  1 
ATOM   1341 H HE3  . LYS A 1 88  ? -21.15900 -27.52100 -1.21700  1.000 59.70819  ? 88  LYS A HE3  1 
ATOM   1342 H HZ1  . LYS A 1 88  ? -19.67400 -27.41300 0.49700   1.000 61.79819  ? 88  LYS A HZ1  1 
ATOM   1343 H HZ2  . LYS A 1 88  ? -20.48600 -28.60400 0.63100   1.000 61.79819  ? 88  LYS A HZ2  1 
ATOM   1344 H HZ3  . LYS A 1 88  ? -19.12400 -28.70600 0.14800   1.000 61.79819  ? 88  LYS A HZ3  1 
ATOM   1345 N N    . ARG A 1 89  ? -22.35300 -29.84300 -6.53900  1.000 39.59805  ? 89  ARG A N    1 
ATOM   1346 C CA   . ARG A 1 89  ? -22.64200 -30.95300 -7.43200  1.000 39.92765  ? 89  ARG A CA   1 
ATOM   1347 C C    . ARG A 1 89  ? -21.95500 -32.23100 -6.95500  1.000 41.89884  ? 89  ARG A C    1 
ATOM   1348 O O    . ARG A 1 89  ? -20.91400 -32.17600 -6.29000  1.000 42.80543  ? 89  ARG A O    1 
ATOM   1349 C CB   . ARG A 1 89  ? -22.19200 -30.61400 -8.85800  1.000 44.07435  ? 89  ARG A CB   1 
ATOM   1350 C CG   . ARG A 1 89  ? -23.21200 -29.76100 -9.60600  1.000 49.85482  ? 89  ARG A CG   1 
ATOM   1351 C CD   . ARG A 1 89  ? -24.46000 -30.56800 -9.95400  1.000 52.41714  ? 89  ARG A CD   1 
ATOM   1352 N NE   . ARG A 1 89  ? -25.60100 -29.72200 -10.28400 1.000 48.14408  ? 89  ARG A NE   1 
ATOM   1353 C CZ   . ARG A 1 89  ? -25.71800 -29.04500 -11.41900 1.000 63.60176  ? 89  ARG A CZ   1 
ATOM   1354 N NH1  . ARG A 1 89  ? -24.75800 -29.05400 -12.32900 1.000 65.99626  ? 89  ARG A NH1  1 
ATOM   1355 N NH2  . ARG A 1 89  ? -26.82600 -28.34400 -11.64600 1.000 67.00953  ? 89  ARG A NH2  1 
ATOM   1356 H H    . ARG A 1 89  ? -21.55200 -29.53800 -6.60800  1.000 49.48819  ? 89  ARG A H    1 
ATOM   1357 H HA   . ARG A 1 89  ? -23.59700 -31.10200 -7.43100  1.000 49.00819  ? 89  ARG A HA   1 
ATOM   1358 H HB2  . ARG A 1 89  ? -21.35800 -30.12000 -8.81800  1.000 52.23819  ? 89  ARG A HB2  1 
ATOM   1359 H HB3  . ARG A 1 89  ? -22.06700 -31.43800 -9.35500  1.000 52.23819  ? 89  ARG A HB3  1 
ATOM   1360 H HG2  . ARG A 1 89  ? -23.47800 -29.01500 -9.04600  1.000 58.82819  ? 89  ARG A HG2  1 
ATOM   1361 H HG3  . ARG A 1 89  ? -22.81700 -29.43900 -10.43100 1.000 58.82819  ? 89  ARG A HG3  1 
ATOM   1362 H HD2  . ARG A 1 89  ? -24.26800 -31.12300 -10.72600 1.000 61.86819  ? 89  ARG A HD2  1 
ATOM   1363 H HD3  . ARG A 1 89  ? -24.71400 -31.12500 -9.20400  1.000 61.86819  ? 89  ARG A HD3  1 
ATOM   1364 H HE   . ARG A 1 89  ? -26.23600 -29.65800 -9.70800  1.000 56.80819  ? 89  ARG A HE   1 
ATOM   1365 H HH11 . ARG A 1 89  ? -24.03900 -29.50500 -12.19500 1.000 75.16819  ? 89  ARG A HH11 1 
ATOM   1366 H HH12 . ARG A 1 89  ? -24.85400 -28.60700 -13.05800 1.000 75.16819  ? 89  ARG A HH12 1 
ATOM   1367 H HH21 . ARG A 1 89  ? -27.45500 -28.33100 -11.05900 1.000 78.07819  ? 89  ARG A HH21 1 
ATOM   1368 H HH22 . ARG A 1 89  ? -26.91100 -27.89900 -12.37700 1.000 78.07819  ? 89  ARG A HH22 1 
ATOM   1369 N N    . PRO A 1 90  ? -22.52300 -33.39800 -7.25300  1.000 43.12062  ? 90  PRO A N    1 
ATOM   1370 C CA   . PRO A 1 90  ? -21.91100 -34.64000 -6.75200  1.000 39.16190  ? 90  PRO A CA   1 
ATOM   1371 C C    . PRO A 1 90  ? -20.46400 -34.79000 -7.18600  1.000 41.10326  ? 90  PRO A C    1 
ATOM   1372 O O    . PRO A 1 90  ? -19.68900 -35.45700 -6.49000  1.000 39.54216  ? 90  PRO A O    1 
ATOM   1373 C CB   . PRO A 1 90  ? -22.80600 -35.74400 -7.33300  1.000 40.04839  ? 90  PRO A CB   1 
ATOM   1374 C CG   . PRO A 1 90  ? -24.06800 -35.04100 -7.79000  1.000 54.16429  ? 90  PRO A CG   1 
ATOM   1375 C CD   . PRO A 1 90  ? -23.66800 -33.64800 -8.15000  1.000 56.57414  ? 90  PRO A CD   1 
ATOM   1376 H HA   . PRO A 1 90  ? -21.95800 -34.66900 -5.78400  1.000 48.71819  ? 90  PRO A HA   1 
ATOM   1377 H HB2  . PRO A 1 90  ? -22.35800 -36.16600 -8.08300  1.000 49.06819  ? 90  PRO A HB2  1 
ATOM   1378 H HB3  . PRO A 1 90  ? -23.00800 -36.39600 -6.64400  1.000 49.06819  ? 90  PRO A HB3  1 
ATOM   1379 H HG2  . PRO A 1 90  ? -24.43200 -35.50000 -8.56300  1.000 66.26819  ? 90  PRO A HG2  1 
ATOM   1380 H HG3  . PRO A 1 90  ? -24.71300 -35.03200 -7.06600  1.000 66.26819  ? 90  PRO A HG3  1 
ATOM   1381 H HD2  . PRO A 1 90  ? -23.39000 -33.60300 -9.07800  1.000 69.16819  ? 90  PRO A HD2  1 
ATOM   1382 H HD3  . PRO A 1 90  ? -24.39500 -33.03500 -7.96300  1.000 69.16819  ? 90  PRO A HD3  1 
ATOM   1383 N N    . THR A 1 91  ? -20.06900 -34.17200 -8.31000  1.000 51.49076  ? 91  THR A N    1 
ATOM   1384 C CA   . THR A 1 91  ? -18.67800 -34.21500 -8.75100  1.000 45.07111  ? 91  THR A CA   1 
ATOM   1385 C C    . THR A 1 91  ? -17.76900 -33.38900 -7.85100  1.000 44.03108  ? 91  THR A C    1 
ATOM   1386 O O    . THR A 1 91  ? -16.54900 -33.57900 -7.88000  1.000 47.02964  ? 91  THR A O    1 
ATOM   1387 C CB   . THR A 1 91  ? -18.53800 -33.71500 -10.20000 1.000 45.67630  ? 91  THR A CB   1 
ATOM   1388 O OG1  . THR A 1 91  ? -18.85300 -32.31700 -10.27100 1.000 44.59872  ? 91  THR A OG1  1 
ATOM   1389 C CG2  . THR A 1 91  ? -19.44300 -34.50800 -11.15500 1.000 47.80919  ? 91  THR A CG2  1 
ATOM   1390 H H    . THR A 1 91  ? -20.58900 -33.72500 -8.82800  1.000 60.96819  ? 91  THR A H    1 
ATOM   1391 H HA   . THR A 1 91  ? -18.36900 -35.13400 -8.72200  1.000 51.92819  ? 91  THR A HA   1 
ATOM   1392 H HB   . THR A 1 91  ? -17.62000 -33.84300 -10.48700 1.000 50.89819  ? 91  THR A HB   1 
ATOM   1393 H HG1  . THR A 1 91  ? -18.77600 -32.04500 -11.06200 1.000 50.05819  ? 91  THR A HG1  1 
ATOM   1394 H HG21 . THR A 1 91  ? -19.30100 -34.21300 -12.06800 1.000 52.41819  ? 91  THR A HG21 1 
ATOM   1395 H HG22 . THR A 1 91  ? -19.23900 -35.45400 -11.09400 1.000 52.41819  ? 91  THR A HG22 1 
ATOM   1396 H HG23 . THR A 1 91  ? -20.37400 -34.37100 -10.92100 1.000 52.41819  ? 91  THR A HG23 1 
ATOM   1397 N N    . GLY A 1 92  ? -18.33600 -32.49200 -7.04400  1.000 37.67029  ? 92  GLY A N    1 
ATOM   1398 C CA   . GLY A 1 92  ? -17.58500 -31.57200 -6.22500  1.000 38.24930  ? 92  GLY A CA   1 
ATOM   1399 C C    . GLY A 1 92  ? -17.65200 -30.14200 -6.71600  1.000 42.50768  ? 92  GLY A C    1 
ATOM   1400 O O    . GLY A 1 92  ? -17.38400 -29.21500 -5.93800  1.000 42.89256  ? 92  GLY A O    1 
ATOM   1401 H H    . GLY A 1 92  ? -19.18700 -32.40100 -6.95800  1.000 46.14819  ? 92  GLY A H    1 
ATOM   1402 H HA2  . GLY A 1 92  ? -17.93000 -31.59800 -5.31900  1.000 47.25819  ? 92  GLY A HA2  1 
ATOM   1403 H HA3  . GLY A 1 92  ? -16.65400 -31.84300 -6.20300  1.000 47.25819  ? 92  GLY A HA3  1 
ATOM   1404 N N    . GLU A 1 93  ? -18.00600 -29.94300 -7.98600  1.000 48.77620  ? 93  GLU A N    1 
ATOM   1405 C CA   . GLU A 1 93  ? -18.00100 -28.60500 -8.55700  1.000 46.95713  ? 93  GLU A CA   1 
ATOM   1406 C C    . GLU A 1 93  ? -19.01300 -27.73900 -7.82400  1.000 46.37107  ? 93  GLU A C    1 
ATOM   1407 O O    . GLU A 1 93  ? -20.02600 -28.22400 -7.31200  1.000 47.48189  ? 93  GLU A O    1 
ATOM   1408 C CB   . GLU A 1 93  ? -18.31100 -28.63900 -10.05800 1.000 52.37875  ? 93  GLU A CB   1 
ATOM   1409 C CG   . GLU A 1 93  ? -18.12400 -27.29400 -10.76600 1.000 54.52413  ? 93  GLU A CG   1 
ATOM   1410 C CD   . GLU A 1 93  ? -18.11300 -27.42100 -12.27400 1.000 66.39554  ? 93  GLU A CD   1 
ATOM   1411 O OE1  . GLU A 1 93  ? -17.89300 -28.54100 -12.78400 1.000 72.90022  ? 93  GLU A OE1  1 
ATOM   1412 O OE2  . GLU A 1 93  ? -18.33400 -26.39600 -12.95000 1.000 75.65514  ? 93  GLU A OE2  1 
ATOM   1413 H H    . GLU A 1 93  ? -18.25000 -30.56200 -8.53100  1.000 54.01819  ? 93  GLU A H    1 
ATOM   1414 H HA   . GLU A 1 93  ? -17.12300 -28.21100 -8.43800  1.000 51.14819  ? 93  GLU A HA   1 
ATOM   1415 H HB2  . GLU A 1 93  ? -17.72100 -29.28200 -10.48100 1.000 56.07819  ? 93  GLU A HB2  1 
ATOM   1416 H HB3  . GLU A 1 93  ? -19.23400 -28.91100 -10.18000 1.000 56.07819  ? 93  GLU A HB3  1 
ATOM   1417 H HG2  . GLU A 1 93  ? -18.85300 -26.70400 -10.52000 1.000 57.45819  ? 93  GLU A HG2  1 
ATOM   1418 H HG3  . GLU A 1 93  ? -17.27800 -26.90800 -10.49200 1.000 57.45819  ? 93  GLU A HG3  1 
ATOM   1419 N N    . LEU A 1 94  ? -18.69800 -26.45300 -7.73400  1.000 53.42253  ? 94  LEU A N    1 
ATOM   1420 C CA   . LEU A 1 94  ? -19.51700 -25.46900 -7.04100  1.000 50.82504  ? 94  LEU A CA   1 
ATOM   1421 C C    . LEU A 1 94  ? -20.19500 -24.58400 -8.07700  1.000 49.51870  ? 94  LEU A C    1 
ATOM   1422 O O    . LEU A 1 94  ? -19.51500 -23.93900 -8.88200  1.000 52.67964  ? 94  LEU A O    1 
ATOM   1423 C CB   . LEU A 1 94  ? -18.66300 -24.61500 -6.10600  1.000 50.70863  ? 94  LEU A CB   1 
ATOM   1424 C CG   . LEU A 1 94  ? -17.65200 -25.32700 -5.20400  1.000 50.63368  ? 94  LEU A CG   1 
ATOM   1425 C CD1  . LEU A 1 94  ? -16.93900 -24.30200 -4.33400  1.000 53.29816  ? 94  LEU A CD1  1 
ATOM   1426 C CD2  . LEU A 1 94  ? -18.34300 -26.38000 -4.36600  1.000 52.40698  ? 94  LEU A CD2  1 
ATOM   1427 H H    . LEU A 1 94  ? -17.98700 -26.11500 -8.08000  1.000 59.34819  ? 94  LEU A H    1 
ATOM   1428 H HA   . LEU A 1 94  ? -20.20000 -25.91700 -6.51800  1.000 57.24819  ? 94  LEU A HA   1 
ATOM   1429 H HB2  . LEU A 1 94  ? -18.16200 -23.98700 -6.65000  1.000 57.06819  ? 94  LEU A HB2  1 
ATOM   1430 H HB3  . LEU A 1 94  ? -19.26100 -24.12100 -5.52400  1.000 57.06819  ? 94  LEU A HB3  1 
ATOM   1431 H HG   . LEU A 1 94  ? -16.98800 -25.76800 -5.75700  1.000 57.19819  ? 94  LEU A HG   1 
ATOM   1432 H HD11 . LEU A 1 94  ? -16.32600 -24.76400 -3.74100  1.000 60.05819  ? 94  LEU A HD11 1 
ATOM   1433 H HD12 . LEU A 1 94  ? -16.45000 -23.69000 -4.90500  1.000 60.05819  ? 94  LEU A HD12 1 
ATOM   1434 H HD13 . LEU A 1 94  ? -17.59800 -23.81600 -3.81500  1.000 60.05819  ? 94  LEU A HD13 1 
ATOM   1435 H HD21 . LEU A 1 94  ? -17.70200 -26.75800 -3.74300  1.000 60.80819  ? 94  LEU A HD21 1 
ATOM   1436 H HD22 . LEU A 1 94  ? -19.07300 -25.96700 -3.88000  1.000 60.80819  ? 94  LEU A HD22 1 
ATOM   1437 H HD23 . LEU A 1 94  ? -18.68600 -27.07400 -4.95000  1.000 60.80819  ? 94  LEU A HD23 1 
ATOM   1438 N N    . MET A 1 95  ? -21.52600 -24.53800 -8.04800  1.000 47.85527  ? 95  MET A N    1 
ATOM   1439 C CA   . MET A 1 95  ? -22.30300 -23.71700 -8.97300  1.000 51.96419  ? 95  MET A CA   1 
ATOM   1440 C C    . MET A 1 95  ? -23.09600 -22.67800 -8.19500  1.000 51.56830  ? 95  MET A C    1 
ATOM   1441 O O    . MET A 1 95  ? -24.25900 -22.91400 -7.83500  1.000 54.29380  ? 95  MET A O    1 
ATOM   1442 C CB   . MET A 1 95  ? -23.26100 -24.55400 -9.81800  1.000 51.27736  ? 95  MET A CB   1 
ATOM   1443 C CG   . MET A 1 95  ? -22.61400 -25.66700 -10.60200 1.000 65.82336  ? 95  MET A CG   1 
ATOM   1444 S SD   . MET A 1 95  ? -23.36400 -25.97000 -12.22900 1.000 74.44111  ? 95  MET A SD   1 
ATOM   1445 C CE   . MET A 1 95  ? -25.03800 -25.33300 -12.03900 1.000 62.32518  ? 95  MET A CE   1 
ATOM   1446 H H    . MET A 1 95  ? -22.00900 -24.98100 -7.49200  1.000 53.85819  ? 95  MET A H    1 
ATOM   1447 H HA   . MET A 1 95  ? -21.69900 -23.26600 -9.58200  1.000 57.96819  ? 95  MET A HA   1 
ATOM   1448 H HB2  . MET A 1 95  ? -23.93000 -24.94900 -9.23700  1.000 56.92819  ? 95  MET A HB2  1 
ATOM   1449 H HB3  . MET A 1 95  ? -23.68300 -23.94800 -10.44300 1.000 56.92819  ? 95  MET A HB3  1 
ATOM   1450 H HG2  . MET A 1 95  ? -21.68100 -25.44500 -10.74400 1.000 73.33819  ? 95  MET A HG2  1 
ATOM   1451 H HG3  . MET A 1 95  ? -22.68100 -26.48800 -10.08900 1.000 73.33819  ? 95  MET A HG3  1 
ATOM   1452 H HE1  . MET A 1 95  ? -25.37900 -25.58800 -11.16800 1.000 68.24819  ? 95  MET A HE1  1 
ATOM   1453 H HE2  . MET A 1 95  ? -25.02000 -24.36800 -12.12200 1.000 68.24819  ? 95  MET A HE2  1 
ATOM   1454 H HE3  . MET A 1 95  ? -25.59700 -25.71000 -12.73600 1.000 68.24819  ? 95  MET A HE3  1 
ATOM   1455 N N    . PRO A 1 96  ? -22.50700 -21.52100 -7.90300  1.000 50.81504  ? 96  PRO A N    1 
ATOM   1456 C CA   . PRO A 1 96  ? -23.31500 -20.38500 -7.44400  1.000 49.45958  ? 96  PRO A CA   1 
ATOM   1457 C C    . PRO A 1 96  ? -24.20500 -19.89500 -8.58000  1.000 47.24027  ? 96  PRO A C    1 
ATOM   1458 O O    . PRO A 1 96  ? -23.72400 -19.61700 -9.67800  1.000 46.00945  ? 96  PRO A O    1 
ATOM   1459 C CB   . PRO A 1 96  ? -22.27200 -19.33700 -7.04300  1.000 42.67865  ? 96  PRO A CB   1 
ATOM   1460 C CG   . PRO A 1 96  ? -21.05400 -19.71000 -7.80500  1.000 52.40637  ? 96  PRO A CG   1 
ATOM   1461 C CD   . PRO A 1 96  ? -21.07100 -21.20000 -7.96600  1.000 50.53596  ? 96  PRO A CD   1 
ATOM   1462 H HA   . PRO A 1 96  ? -23.85500 -20.62900 -6.67600  1.000 62.68819  ? 96  PRO A HA   1 
ATOM   1463 H HB2  . PRO A 1 96  ? -22.58000 -18.45300 -7.29700  1.000 53.63819  ? 96  PRO A HB2  1 
ATOM   1464 H HB3  . PRO A 1 96  ? -22.10900 -19.38500 -6.08800  1.000 53.63819  ? 96  PRO A HB3  1 
ATOM   1465 H HG2  . PRO A 1 96  ? -21.07400 -19.27700 -8.67300  1.000 64.02819  ? 96  PRO A HG2  1 
ATOM   1466 H HG3  . PRO A 1 96  ? -20.26800 -19.43400 -7.30800  1.000 64.02819  ? 96  PRO A HG3  1 
ATOM   1467 H HD2  . PRO A 1 96  ? -20.70100 -21.44800 -8.82700  1.000 62.53819  ? 96  PRO A HD2  1 
ATOM   1468 H HD3  . PRO A 1 96  ? -20.59500 -21.62600 -7.23600  1.000 62.53819  ? 96  PRO A HD3  1 
ATOM   1469 N N    . LEU A 1 97  ? -25.50900 -19.81700 -8.32000  1.000 60.74996  ? 97  LEU A N    1 
ATOM   1470 C CA   . LEU A 1 97  ? -26.47700 -19.37000 -9.31600  1.000 49.17312  ? 97  LEU A CA   1 
ATOM   1471 C C    . LEU A 1 97  ? -27.21000 -18.13900 -8.79800  1.000 50.08590  ? 97  LEU A C    1 
ATOM   1472 O O    . LEU A 1 97  ? -27.58500 -18.08000 -7.62200  1.000 44.18121  ? 97  LEU A O    1 
ATOM   1473 C CB   . LEU A 1 97  ? -27.49400 -20.46000 -9.64700  1.000 44.44068  ? 97  LEU A CB   1 
ATOM   1474 C CG   . LEU A 1 97  ? -27.00300 -21.74100 -10.31500 1.000 50.57158  ? 97  LEU A CG   1 
ATOM   1475 C CD1  . LEU A 1 97  ? -28.24400 -22.55800 -10.69900 1.000 59.42542  ? 97  LEU A CD1  1 
ATOM   1476 C CD2  . LEU A 1 97  ? -26.14400 -21.51800 -11.52000 1.000 49.71255  ? 97  LEU A CD2  1 
ATOM   1477 H H    . LEU A 1 97  ? -25.86100 -20.02100 -7.56200  1.000 70.69819  ? 97  LEU A H    1 
ATOM   1478 H HA   . LEU A 1 97  ? -26.01500 -19.12600 -10.13300 1.000 55.88819  ? 97  LEU A HA   1 
ATOM   1479 H HB2  . LEU A 1 97  ? -27.92400 -20.72400 -8.82000  1.000 50.81819  ? 97  LEU A HB2  1 
ATOM   1480 H HB3  . LEU A 1 97  ? -28.15900 -20.07400 -10.23800 1.000 50.81819  ? 97  LEU A HB3  1 
ATOM   1481 H HG   . LEU A 1 97  ? -26.49100 -22.25700 -9.67200  1.000 57.78819  ? 97  LEU A HG   1 
ATOM   1482 H HD11 . LEU A 1 97  ? -27.95900 -23.39200 -11.10500 1.000 68.62819  ? 97  LEU A HD11 1 
ATOM   1483 H HD12 . LEU A 1 97  ? -28.76200 -22.73900 -9.89900  1.000 68.62819  ? 97  LEU A HD12 1 
ATOM   1484 H HD13 . LEU A 1 97  ? -28.77600 -22.04700 -11.32900 1.000 68.62819  ? 97  LEU A HD13 1 
ATOM   1485 H HD21 . LEU A 1 97  ? -25.99200 -22.36800 -11.96100 1.000 54.77819  ? 97  LEU A HD21 1 
ATOM   1486 H HD22 . LEU A 1 97  ? -26.60000 -20.91000 -12.12300 1.000 54.77819  ? 97  LEU A HD22 1 
ATOM   1487 H HD23 . LEU A 1 97  ? -25.29900 -21.13300 -11.23900 1.000 54.77819  ? 97  LEU A HD23 1 
ATOM   1488 N N    . ALA A 1 98  ? -27.41300 -17.15300 -9.67100  1.000 44.07407  ? 98  ALA A N    1 
ATOM   1489 C CA   . ALA A 1 98  ? -28.15800 -15.95700 -9.30200  1.000 43.81995  ? 98  ALA A CA   1 
ATOM   1490 C C    . ALA A 1 98  ? -29.64000 -16.16100 -9.57200  1.000 52.83460  ? 98  ALA A C    1 
ATOM   1491 O O    . ALA A 1 98  ? -30.03000 -16.53900 -10.68500 1.000 57.74473  ? 98  ALA A O    1 
ATOM   1492 C CB   . ALA A 1 98  ? -27.66600 -14.73700 -10.07500 1.000 50.10747  ? 98  ALA A CB   1 
ATOM   1493 H H    . ALA A 1 98  ? -27.12900 -17.15500 -10.48300 1.000 52.96819  ? 98  ALA A H    1 
ATOM   1494 H HA   . ALA A 1 98  ? -28.04100 -15.78400 -8.35500  1.000 52.44819  ? 98  ALA A HA   1 
ATOM   1495 H HB1  . ALA A 1 98  ? -28.18300 -13.96200 -9.80400  1.000 57.88819  ? 98  ALA A HB1  1 
ATOM   1496 H HB2  . ALA A 1 98  ? -26.72700 -14.59500 -9.87600  1.000 57.88819  ? 98  ALA A HB2  1 
ATOM   1497 H HB3  . ALA A 1 98  ? -27.78200 -14.89700 -11.02500 1.000 57.88819  ? 98  ALA A HB3  1 
ATOM   1498 N N    . ALA A 1 99  ? -30.46500 -15.89000 -8.56200  1.000 57.05441  ? 99  ALA A N    1 
ATOM   1499 C CA   . ALA A 1 99  ? -31.91100 -16.02600 -8.67300  1.000 48.93556  ? 99  ALA A CA   1 
ATOM   1500 C C    . ALA A 1 99  ? -32.56900 -14.78000 -8.11300  1.000 43.13178  ? 99  ALA A C    1 
ATOM   1501 O O    . ALA A 1 99  ? -32.39700 -14.46400 -6.92800  1.000 46.44528  ? 99  ALA A O    1 
ATOM   1502 C CB   . ALA A 1 99  ? -32.40300 -17.27200 -7.93200  1.000 39.13454  ? 99  ALA A CB   1 
ATOM   1503 H H    . ALA A 1 99  ? -30.20300 -15.62100 -7.78800  1.000 67.36819  ? 99  ALA A H    1 
ATOM   1504 H HA   . ALA A 1 99  ? -32.15900 -16.10800 -9.60700  1.000 57.91819  ? 99  ALA A HA   1 
ATOM   1505 H HB1  . ALA A 1 99  ? -33.36200 -17.35300 -8.05300  1.000 47.86819  ? 99  ALA A HB1  1 
ATOM   1506 H HB2  . ALA A 1 99  ? -31.95600 -18.05200 -8.29400  1.000 47.86819  ? 99  ALA A HB2  1 
ATOM   1507 H HB3  . ALA A 1 99  ? -32.19400 -17.18100 -6.98900  1.000 47.86819  ? 99  ALA A HB3  1 
ATOM   1508 N N    . ARG A 1 100 ? -33.29900 -14.05700 -8.96000  1.000 40.53453  ? 100 ARG A N    1 
ATOM   1509 C CA   . ARG A 1 100 ? -34.10100 -12.94000 -8.48500  1.000 40.12507  ? 100 ARG A CA   1 
ATOM   1510 C C    . ARG A 1 100 ? -35.38000 -13.48100 -7.85800  1.000 39.84975  ? 100 ARG A C    1 
ATOM   1511 O O    . ARG A 1 100 ? -36.23800 -14.04500 -8.54900  1.000 40.15484  ? 100 ARG A O    1 
ATOM   1512 C CB   . ARG A 1 100 ? -34.43700 -11.95600 -9.60100  1.000 50.46415  ? 100 ARG A CB   1 
ATOM   1513 C CG   . ARG A 1 100 ? -35.08200 -10.67400 -9.07100  1.000 54.87396  ? 100 ARG A CG   1 
ATOM   1514 C CD   . ARG A 1 100 ? -34.43500 -9.45800  -9.68000  1.000 55.11068  ? 100 ARG A CD   1 
ATOM   1515 N NE   . ARG A 1 100 ? -34.36500 -9.59500  -11.12700 1.000 66.11035  ? 100 ARG A NE   1 
ATOM   1516 C CZ   . ARG A 1 100 ? -33.44300 -9.02300  -11.88600 1.000 78.06666  ? 100 ARG A CZ   1 
ATOM   1517 N NH1  . ARG A 1 100 ? -32.48300 -8.27600  -11.36300 1.000 77.19571  ? 100 ARG A NH1  1 
ATOM   1518 N NH2  . ARG A 1 100 ? -33.48200 -9.20800  -13.20300 1.000 82.01205  ? 100 ARG A NH2  1 
ATOM   1519 H H    . ARG A 1 100 ? -33.34500 -14.19400 -9.80800  1.000 52.16819  ? 100 ARG A H    1 
ATOM   1520 H HA   . ARG A 1 100 ? -33.60700 -12.46300 -7.80000  1.000 51.24819  ? 100 ARG A HA   1 
ATOM   1521 H HB2  . ARG A 1 100 ? -33.61800 -11.71800 -10.06200 1.000 61.57819  ? 100 ARG A HB2  1 
ATOM   1522 H HB3  . ARG A 1 100 ? -35.05800 -12.37400 -10.21700 1.000 61.57819  ? 100 ARG A HB3  1 
ATOM   1523 H HG2  . ARG A 1 100 ? -36.02400 -10.66800 -9.30300  1.000 66.15819  ? 100 ARG A HG2  1 
ATOM   1524 H HG3  . ARG A 1 100 ? -34.97100 -10.63000 -8.10800  1.000 66.15819  ? 100 ARG A HG3  1 
ATOM   1525 H HD2  . ARG A 1 100 ? -34.96100 -8.67100  -9.47000  1.000 64.36819  ? 100 ARG A HD2  1 
ATOM   1526 H HD3  . ARG A 1 100 ? -33.53600 -9.37000  -9.32900  1.000 64.36819  ? 100 ARG A HD3  1 
ATOM   1527 H HE   . ARG A 1 100 ? -34.96300 -10.07700 -11.51500 1.000 76.06819  ? 100 ARG A HE   1 
ATOM   1528 H HH11 . ARG A 1 100 ? -32.44500 -8.14700  -10.51400 1.000 87.13819  ? 100 ARG A HH11 1 
ATOM   1529 H HH12 . ARG A 1 100 ? -31.89500 -7.91500  -11.87600 1.000 87.13819  ? 100 ARG A HH12 1 
ATOM   1530 H HH21 . ARG A 1 100 ? -34.10100 -9.69300  -13.55100 1.000 91.85819  ? 100 ARG A HH21 1 
ATOM   1531 H HH22 . ARG A 1 100 ? -32.88800 -8.84300  -13.70600 1.000 91.85819  ? 100 ARG A HH22 1 
ATOM   1532 N N    . MET A 1 101 ? -35.52200 -13.27800 -6.55700  1.000 48.95752  ? 101 MET A N    1 
ATOM   1533 C CA   . MET A 1 101 ? -36.63800 -13.84700 -5.82300  1.000 47.24621  ? 101 MET A CA   1 
ATOM   1534 C C    . MET A 1 101 ? -37.88900 -13.01000 -6.02000  1.000 47.31874  ? 101 MET A C    1 
ATOM   1535 O O    . MET A 1 101 ? -37.82200 -11.79800 -6.23500  1.000 53.05349  ? 101 MET A O    1 
ATOM   1536 C CB   . MET A 1 101 ? -36.29700 -13.93600 -4.33900  1.000 49.84465  ? 101 MET A CB   1 
ATOM   1537 C CG   . MET A 1 101 ? -34.93000 -14.54400 -4.07600  1.000 46.69030  ? 101 MET A CG   1 
ATOM   1538 S SD   . MET A 1 101 ? -34.70000 -16.17700 -4.81600  1.000 48.43854  ? 101 MET A SD   1 
ATOM   1539 C CE   . MET A 1 101 ? -36.04800 -17.09500 -4.09500  1.000 41.76139  ? 101 MET A CE   1 
ATOM   1540 H H    . MET A 1 101 ? -34.98400 -12.81100 -6.07500  1.000 52.30819  ? 101 MET A H    1 
ATOM   1541 H HA   . MET A 1 101 ? -36.80500 -14.74500 -6.14800  1.000 51.33819  ? 101 MET A HA   1 
ATOM   1542 H HB2  . MET A 1 101 ? -36.31300 -13.04600 -3.95300  1.000 55.55819  ? 101 MET A HB2  1 
ATOM   1543 H HB3  . MET A 1 101 ? -36.95300 -14.50100 -3.90700  1.000 55.55819  ? 101 MET A HB3  1 
ATOM   1544 H HG2  . MET A 1 101 ? -34.24800 -13.95600 -4.43500  1.000 52.44819  ? 101 MET A HG2  1 
ATOM   1545 H HG3  . MET A 1 101 ? -34.81100 -14.63600 -3.11800  1.000 52.44819  ? 101 MET A HG3  1 
ATOM   1546 H HE1  . MET A 1 101 ? -35.96900 -18.02600 -4.35400  1.000 48.43819  ? 101 MET A HE1  1 
ATOM   1547 H HE2  . MET A 1 101 ? -36.00300 -17.01500 -3.12900  1.000 48.43819  ? 101 MET A HE2  1 
ATOM   1548 H HE3  . MET A 1 101 ? -36.88700 -16.73100 -4.41900  1.000 48.43819  ? 101 MET A HE3  1 
ATOM   1549 N N    . GLY A 1 102 ? -39.04000 -13.67100 -5.93400  1.000 40.21526  ? 102 GLY A N    1 
ATOM   1550 C CA   . GLY A 1 102 ? -40.30300 -13.00500 -6.16500  1.000 42.12247  ? 102 GLY A CA   1 
ATOM   1551 C C    . GLY A 1 102 ? -41.36500 -13.29600 -5.12700  1.000 41.15764  ? 102 GLY A C    1 
ATOM   1552 O O    . GLY A 1 102 ? -41.10300 -13.24200 -3.92200  1.000 41.90359  ? 102 GLY A O    1 
ATOM   1553 H H    . GLY A 1 102 ? -39.11000 -14.50700 -5.74300  1.000 48.88819  ? 102 GLY A H    1 
ATOM   1554 H HA2  . GLY A 1 102 ? -40.16200 -12.04600 -6.18500  1.000 50.18819  ? 102 GLY A HA2  1 
ATOM   1555 H HA3  . GLY A 1 102 ? -40.64800 -13.27600 -7.03000  1.000 50.18819  ? 102 GLY A HA3  1 
ATOM   1556 N N    . THR A 1 103 ? -42.57000 -13.61400 -5.59800  1.000 45.60082  ? 103 THR A N    1 
ATOM   1557 C CA   . THR A 1 103 ? -43.72100 -13.76000 -4.71800  1.000 37.94550  ? 103 THR A CA   1 
ATOM   1558 C C    . THR A 1 103 ? -43.47100 -14.82100 -3.65800  1.000 33.76261  ? 103 THR A C    1 
ATOM   1559 O O    . THR A 1 103 ? -43.02900 -15.93100 -3.96600  1.000 32.54167  ? 103 THR A O    1 
ATOM   1560 C CB   . THR A 1 103 ? -44.95900 -14.13300 -5.53700  1.000 42.66754  ? 103 THR A CB   1 
ATOM   1561 O OG1  . THR A 1 103 ? -45.32800 -13.04000 -6.38100  1.000 47.65586  ? 103 THR A OG1  1 
ATOM   1562 C CG2  . THR A 1 103 ? -46.12700 -14.46900 -4.64300  1.000 53.84811  ? 103 THR A CG2  1 
ATOM   1563 H H    . THR A 1 103 ? -42.74500 -13.75100 -6.42900  1.000 57.96819  ? 103 THR A H    1 
ATOM   1564 H HA   . THR A 1 103 ? -43.89300 -12.91600 -4.27100  1.000 49.06819  ? 103 THR A HA   1 
ATOM   1565 H HB   . THR A 1 103 ? -44.76000 -14.90900 -6.08400  1.000 53.87819  ? 103 THR A HB   1 
ATOM   1566 H HG1  . THR A 1 103 ? -45.50100 -12.36300 -5.91500  1.000 58.21819  ? 103 THR A HG1  1 
ATOM   1567 H HG21 . THR A 1 103 ? -46.95600 -14.39000 -5.14000  1.000 67.54819  ? 103 THR A HG21 1 
ATOM   1568 H HG22 . THR A 1 103 ? -46.04500 -15.37700 -4.31300  1.000 67.54819  ? 103 THR A HG22 1 
ATOM   1569 H HG23 . THR A 1 103 ? -46.15300 -13.85800 -3.89000  1.000 67.54819  ? 103 THR A HG23 1 
ATOM   1570 N N    . HIS A 1 104 ? -43.74300 -14.46600 -2.40200  1.000 49.22132  ? 104 HIS A N    1 
ATOM   1571 C CA   . HIS A 1 104 ? -43.88000 -15.44500 -1.33200  1.000 43.35063  ? 104 HIS A CA   1 
ATOM   1572 C C    . HIS A 1 104 ? -45.28800 -16.02300 -1.38700  1.000 43.84272  ? 104 HIS A C    1 
ATOM   1573 O O    . HIS A 1 104 ? -46.26600 -15.26800 -1.37000  1.000 46.37105  ? 104 HIS A O    1 
ATOM   1574 C CB   . HIS A 1 104 ? -43.66300 -14.81800 0.04600   1.000 47.16625  ? 104 HIS A CB   1 
ATOM   1575 C CG   . HIS A 1 104 ? -42.32900 -14.17000 0.23000   1.000 45.60515  ? 104 HIS A CG   1 
ATOM   1576 N ND1  . HIS A 1 104 ? -41.41400 -14.60500 1.16500   1.000 48.54304  ? 104 HIS A ND1  1 
ATOM   1577 C CD2  . HIS A 1 104 ? -41.76600 -13.10300 -0.38100  1.000 54.18090  ? 104 HIS A CD2  1 
ATOM   1578 C CE1  . HIS A 1 104 ? -40.33900 -13.84000 1.11400   1.000 52.71822  ? 104 HIS A CE1  1 
ATOM   1579 N NE2  . HIS A 1 104 ? -40.52500 -12.92300 0.18300   1.000 58.23736  ? 104 HIS A NE2  1 
ATOM   1580 H H    . HIS A 1 104 ? -43.85400 -13.65300 -2.14400  1.000 55.23819  ? 104 HIS A H    1 
ATOM   1581 H HA   . HIS A 1 104 ? -43.24000 -16.16300 -1.45600  1.000 49.26819  ? 104 HIS A HA   1 
ATOM   1582 H HB2  . HIS A 1 104 ? -44.34200 -14.14000 0.18800   1.000 53.88819  ? 104 HIS A HB2  1 
ATOM   1583 H HB3  . HIS A 1 104 ? -43.74800 -15.51100 0.71900   1.000 53.88819  ? 104 HIS A HB3  1 
ATOM   1584 H HD2  . HIS A 1 104 ? -42.14400 -12.59300 -1.06100  1.000 61.48819  ? 104 HIS A HD2  1 
ATOM   1585 H HE1  . HIS A 1 104 ? -39.57900 -13.93200 1.64100   1.000 61.03819  ? 104 HIS A HE1  1 
ATOM   1586 H HE2  . HIS A 1 104 ? -39.96200 -12.31000 -0.03400  1.000 66.64819  ? 104 HIS A HE2  1 
ATOM   1587 N N    . ALA A 1 105 ? -45.41000 -17.34600 -1.43000  1.000 39.08695  ? 105 ALA A N    1 
ATOM   1588 C CA   . ALA A 1 105 ? -46.75300 -17.91000 -1.38000  1.000 35.88834  ? 105 ALA A CA   1 
ATOM   1589 C C    . ALA A 1 105 ? -46.70800 -19.35900 -0.92500  1.000 36.92104  ? 105 ALA A C    1 
ATOM   1590 O O    . ALA A 1 105 ? -45.64700 -19.98400 -0.87900  1.000 45.45322  ? 105 ALA A O    1 
ATOM   1591 C CB   . ALA A 1 105 ? -47.45700 -17.79200 -2.73900  1.000 41.75598  ? 105 ALA A CB   1 
ATOM   1592 H H    . ALA A 1 105 ? -44.76600 -17.91400 -1.48500  1.000 48.27819  ? 105 ALA A H    1 
ATOM   1593 H HA   . ALA A 1 105 ? -47.27600 -17.41400 -0.73100  1.000 43.94819  ? 105 ALA A HA   1 
ATOM   1594 H HB1  . ALA A 1 105 ? -48.33000 -18.21100 -2.68300  1.000 49.87819  ? 105 ALA A HB1  1 
ATOM   1595 H HB2  . ALA A 1 105 ? -47.55200 -16.85400 -2.96600  1.000 49.87819  ? 105 ALA A HB2  1 
ATOM   1596 H HB3  . ALA A 1 105 ? -46.92000 -18.24200 -3.41000  1.000 49.87819  ? 105 ALA A HB3  1 
ATOM   1597 N N    . THR A 1 106 ? -47.88100 -19.87000 -0.55100  1.000 38.01035  ? 106 THR A N    1 
ATOM   1598 C CA   . THR A 1 106 ? -48.10200 -21.29900 -0.37700  1.000 37.48721  ? 106 THR A CA   1 
ATOM   1599 C C    . THR A 1 106 ? -48.46600 -21.85400 -1.74200  1.000 46.49002  ? 106 THR A C    1 
ATOM   1600 O O    . THR A 1 106 ? -49.44200 -21.40600 -2.35300  1.000 58.55964  ? 106 THR A O    1 
ATOM   1601 C CB   . THR A 1 106 ? -49.22000 -21.59200 0.61900   1.000 41.58895  ? 106 THR A CB   1 
ATOM   1602 O OG1  . THR A 1 106 ? -48.81600 -21.17100 1.92000   1.000 47.84953  ? 106 THR A OG1  1 
ATOM   1603 C CG2  . THR A 1 106 ? -49.53200 -23.07700 0.67300   1.000 61.01244  ? 106 THR A CG2  1 
ATOM   1604 H H    . THR A 1 106 ? -48.57900 -19.39400 -0.38900  1.000 50.14819  ? 106 THR A H    1 
ATOM   1605 H HA   . THR A 1 106 ? -47.28700 -21.72600 -0.07000  1.000 49.80819  ? 106 THR A HA   1 
ATOM   1606 H HB   . THR A 1 106 ? -50.02200 -21.11400 0.35700   1.000 54.18819  ? 106 THR A HB   1 
ATOM   1607 H HG1  . THR A 1 106 ? -49.42600 -21.32900 2.47500   1.000 62.13819  ? 106 THR A HG1  1 
ATOM   1608 H HG21 . THR A 1 106 ? -50.11400 -23.26400 1.42600   1.000 77.45819  ? 106 THR A HG21 1 
ATOM   1609 H HG22 . THR A 1 106 ? -49.97500 -23.35900 -0.14200  1.000 77.45819  ? 106 THR A HG22 1 
ATOM   1610 H HG23 . THR A 1 106 ? -48.71100 -23.58300 0.77800   1.000 77.45819  ? 106 THR A HG23 1 
ATOM   1611 N N    . MET A 1 107 ? -47.68800 -22.81000 -2.22300  1.000 51.38518  ? 107 MET A N    1 
ATOM   1612 C CA   . MET A 1 107 ? -47.83000 -23.30600 -3.58000  1.000 51.03558  ? 107 MET A CA   1 
ATOM   1613 C C    . MET A 1 107 ? -48.27800 -24.75800 -3.59200  1.000 54.25106  ? 107 MET A C    1 
ATOM   1614 O O    . MET A 1 107 ? -47.97100 -25.53100 -2.68000  1.000 54.15545  ? 107 MET A O    1 
ATOM   1615 C CB   . MET A 1 107 ? -46.51100 -23.18400 -4.34100  1.000 53.61089  ? 107 MET A CB   1 
ATOM   1616 C CG   . MET A 1 107 ? -46.20000 -21.77800 -4.81500  1.000 62.95645  ? 107 MET A CG   1 
ATOM   1617 S SD   . MET A 1 107 ? -44.42600 -21.48600 -4.87000  1.000 50.40834  ? 107 MET A SD   1 
ATOM   1618 C CE   . MET A 1 107 ? -44.04400 -21.49900 -3.11800  1.000 46.83975  ? 107 MET A CE   1 
ATOM   1619 H H    . MET A 1 107 ? -47.06100 -23.19300 -1.77600  1.000 60.33819  ? 107 MET A H    1 
ATOM   1620 H HA   . MET A 1 107 ? -48.49100 -22.77100 -4.04700  1.000 59.07819  ? 107 MET A HA   1 
ATOM   1621 H HB2  . MET A 1 107 ? -45.79100 -23.48500 -3.76900  1.000 62.62819  ? 107 MET A HB2  1 
ATOM   1622 H HB3  . MET A 1 107 ? -46.55700 -23.75100 -5.12600  1.000 62.62819  ? 107 MET A HB3  1 
ATOM   1623 H HG2  . MET A 1 107 ? -46.55700 -21.65400 -5.70800  1.000 73.51819  ? 107 MET A HG2  1 
ATOM   1624 H HG3  . MET A 1 107 ? -46.59500 -21.13800 -4.20300  1.000 73.51819  ? 107 MET A HG3  1 
ATOM   1625 H HE1  . MET A 1 107 ? -43.08000 -21.50500 -3.00900  1.000 56.50819  ? 107 MET A HE1  1 
ATOM   1626 H HE2  . MET A 1 107 ? -44.41300 -20.69900 -2.71600  1.000 56.50819  ? 107 MET A HE2  1 
ATOM   1627 H HE3  . MET A 1 107 ? -44.42500 -22.28700 -2.70300  1.000 56.50819  ? 107 MET A HE3  1 
ATOM   1628 N N    . LYS A 1 108 ? -49.03500 -25.10700 -4.63200  1.000 53.24858  ? 108 LYS A N    1 
ATOM   1629 C CA   . LYS A 1 108 ? -49.36200 -26.49200 -4.94900  1.000 56.83575  ? 108 LYS A CA   1 
ATOM   1630 C C    . LYS A 1 108 ? -48.30900 -26.97600 -5.94100  1.000 53.90198  ? 108 LYS A C    1 
ATOM   1631 O O    . LYS A 1 108 ? -48.25600 -26.50200 -7.08100  1.000 58.29709  ? 108 LYS A O    1 
ATOM   1632 C CB   . LYS A 1 108 ? -50.77400 -26.61800 -5.52100  1.000 59.98813  ? 108 LYS A CB   1 
ATOM   1633 C CG   . LYS A 1 108 ? -51.89600 -26.44300 -4.48200  1.000 77.83551  ? 108 LYS A CG   1 
ATOM   1634 C CD   . LYS A 1 108 ? -51.99500 -27.62900 -3.49400  1.000 68.79699  ? 108 LYS A CD   1 
ATOM   1635 C CE   . LYS A 1 108 ? -52.35000 -28.91600 -4.24100  1.000 100.30441 ? 108 LYS A CE   1 
ATOM   1636 N NZ   . LYS A 1 108 ? -53.34700 -28.63800 -5.33900  1.000 94.93488  ? 108 LYS A NZ   1 
ATOM   1637 H H    . LYS A 1 108 ? -49.37900 -24.54200 -5.18200  1.000 62.20819  ? 108 LYS A H    1 
ATOM   1638 H HA   . LYS A 1 108 ? -49.30200 -27.03300 -4.14700  1.000 65.78819  ? 108 LYS A HA   1 
ATOM   1639 H HB2  . LYS A 1 108 ? -50.89400 -25.93400 -6.19800  1.000 67.76819  ? 108 LYS A HB2  1 
ATOM   1640 H HB3  . LYS A 1 108 ? -50.86900 -27.49400 -5.92500  1.000 67.76819  ? 108 LYS A HB3  1 
ATOM   1641 H HG2  . LYS A 1 108 ? -51.70900 -25.64600 -3.96100  1.000 88.92819  ? 108 LYS A HG2  1 
ATOM   1642 H HG3  . LYS A 1 108 ? -52.74500 -26.33800 -4.93700  1.000 88.92819  ? 108 LYS A HG3  1 
ATOM   1643 H HD2  . LYS A 1 108 ? -51.14200 -27.75600 -3.05100  1.000 78.36819  ? 108 LYS A HD2  1 
ATOM   1644 H HD3  . LYS A 1 108 ? -52.69200 -27.45000 -2.84300  1.000 78.36819  ? 108 LYS A HD3  1 
ATOM   1645 H HE2  . LYS A 1 108 ? -51.54900 -29.28900 -4.64100  1.000 114.82819 ? 108 LYS A HE2  1 
ATOM   1646 H HE3  . LYS A 1 108 ? -52.74500 -29.54900 -3.62200  1.000 114.82819 ? 108 LYS A HE3  1 
ATOM   1647 H HZ1  . LYS A 1 108 ? -53.68000 -29.40400 -5.64800  1.000 106.53819 ? 108 LYS A HZ1  1 
ATOM   1648 H HZ2  . LYS A 1 108 ? -54.01400 -28.13900 -5.02500  1.000 106.53819 ? 108 LYS A HZ2  1 
ATOM   1649 H HZ3  . LYS A 1 108 ? -52.95200 -28.20400 -6.00800  1.000 106.53819 ? 108 LYS A HZ3  1 
ATOM   1650 N N    . ILE A 1 109 ? -47.44400 -27.88100 -5.48900  1.000 41.44663  ? 109 ILE A N    1 
ATOM   1651 C CA   . ILE A 1 109 ? -46.42600 -28.50700 -6.32600  1.000 45.98102  ? 109 ILE A CA   1 
ATOM   1652 C C    . ILE A 1 109 ? -46.70300 -30.00200 -6.30500  1.000 49.21415  ? 109 ILE A C    1 
ATOM   1653 O O    . ILE A 1 109 ? -46.49500 -30.66700 -5.28300  1.000 51.92870  ? 109 ILE A O    1 
ATOM   1654 C CB   . ILE A 1 109 ? -45.00200 -28.19800 -5.84300  1.000 48.97394  ? 109 ILE A CB   1 
ATOM   1655 C CG1  . ILE A 1 109 ? -44.72200 -26.70100 -5.99900  1.000 49.00385  ? 109 ILE A CG1  1 
ATOM   1656 C CG2  . ILE A 1 109 ? -43.97800 -29.04200 -6.61400  1.000 55.27051  ? 109 ILE A CG2  1 
ATOM   1657 C CD1  . ILE A 1 109 ? -43.76700 -26.12200 -4.96900  1.000 56.22053  ? 109 ILE A CD1  1 
ATOM   1658 H H    . ILE A 1 109 ? -47.42800 -28.15600 -4.67400  1.000 56.35819  ? 109 ILE A H    1 
ATOM   1659 H HA   . ILE A 1 109 ? -46.51500 -28.19100 -7.23900  1.000 61.68819  ? 109 ILE A HA   1 
ATOM   1660 H HB   . ILE A 1 109 ? -44.94100 -28.42500 -4.90200  1.000 66.82819  ? 109 ILE A HB   1 
ATOM   1661 H HG12 . ILE A 1 109 ? -44.33200 -26.55000 -6.87300  1.000 67.21819  ? 109 ILE A HG12 1 
ATOM   1662 H HG13 . ILE A 1 109 ? -45.55900 -26.21600 -5.92800  1.000 67.21819  ? 109 ILE A HG13 1 
ATOM   1663 H HG21 . ILE A 1 109 ? -44.17200 -28.98300 -7.56200  1.000 74.12819  ? 109 ILE A HG21 1 
ATOM   1664 H HG22 . ILE A 1 109 ? -43.08900 -28.69600 -6.43700  1.000 74.12819  ? 109 ILE A HG22 1 
ATOM   1665 H HG23 . ILE A 1 109 ? -44.03800 -29.96400 -6.32200  1.000 74.12819  ? 109 ILE A HG23 1 
ATOM   1666 H HD11 . ILE A 1 109 ? -44.10000 -26.32500 -4.08200  1.000 77.39819  ? 109 ILE A HD11 1 
ATOM   1667 H HD12 . ILE A 1 109 ? -42.89100 -26.52000 -5.09300  1.000 77.39819  ? 109 ILE A HD12 1 
ATOM   1668 H HD13 . ILE A 1 109 ? -43.71400 -25.16100 -5.09200  1.000 77.39819  ? 109 ILE A HD13 1 
ATOM   1669 N N    . GLN A 1 110 ? -47.19800 -30.52800 -7.41900  1.000 51.45495  ? 110 GLN A N    1 
ATOM   1670 C CA   . GLN A 1 110 ? -47.44700 -31.95800 -7.54100  1.000 53.39772  ? 110 GLN A CA   1 
ATOM   1671 C C    . GLN A 1 110 ? -48.37500 -32.44300 -6.42800  1.000 55.92115  ? 110 GLN A C    1 
ATOM   1672 O O    . GLN A 1 110 ? -48.07700 -33.39000 -5.69600  1.000 59.62306  ? 110 GLN A O    1 
ATOM   1673 C CB   . GLN A 1 110 ? -46.12700 -32.73000 -7.53200  1.000 51.82807  ? 110 GLN A CB   1 
ATOM   1674 C CG   . GLN A 1 110 ? -45.16900 -32.33000 -8.62600  1.000 52.32279  ? 110 GLN A CG   1 
ATOM   1675 C CD   . GLN A 1 110 ? -44.16100 -33.41400 -8.95200  1.000 58.33687  ? 110 GLN A CD   1 
ATOM   1676 O OE1  . GLN A 1 110 ? -43.81600 -34.25000 -8.11300  1.000 67.18338  ? 110 GLN A OE1  1 
ATOM   1677 N NE2  . GLN A 1 110 ? -43.68800 -33.40800 -10.18800 1.000 66.33161  ? 110 GLN A NE2  1 
ATOM   1678 H H    . GLN A 1 110 ? -47.39900 -30.07600 -8.12200  1.000 65.37819  ? 110 GLN A H    1 
ATOM   1679 H HA   . GLN A 1 110 ? -47.88600 -32.12900 -8.38900  1.000 66.64819  ? 110 GLN A HA   1 
ATOM   1680 H HB2  . GLN A 1 110 ? -45.68400 -32.58100 -6.68200  1.000 65.42819  ? 110 GLN A HB2  1 
ATOM   1681 H HB3  . GLN A 1 110 ? -46.31900 -33.67500 -7.63900  1.000 65.42819  ? 110 GLN A HB3  1 
ATOM   1682 H HG2  . GLN A 1 110 ? -45.67300 -32.13700 -9.43200  1.000 65.77819  ? 110 GLN A HG2  1 
ATOM   1683 H HG3  . GLN A 1 110 ? -44.68000 -31.54100 -8.34400  1.000 65.77819  ? 110 GLN A HG3  1 
ATOM   1684 H HE21 . GLN A 1 110 ? -43.95300 -32.81000 -10.74700 1.000 81.06819  ? 110 GLN A HE21 1 
ATOM   1685 H HE22 . GLN A 1 110 ? -43.11300 -34.00000 -10.43100 1.000 81.06819  ? 110 GLN A HE22 1 
ATOM   1686 N N    . GLY A 1 111 ? -49.51800 -31.77200 -6.29600  1.000 50.66225  ? 111 GLY A N    1 
ATOM   1687 C CA   . GLY A 1 111 ? -50.49900 -32.14100 -5.29900  1.000 50.59831  ? 111 GLY A CA   1 
ATOM   1688 C C    . GLY A 1 111 ? -50.12300 -31.84900 -3.86300  1.000 60.78477  ? 111 GLY A C    1 
ATOM   1689 O O    . GLY A 1 111 ? -51.01400 -31.81700 -3.00700  1.000 76.86431  ? 111 GLY A O    1 
ATOM   1690 H H    . GLY A 1 111 ? -49.74400 -31.09600 -6.77800  1.000 69.06819  ? 111 GLY A H    1 
ATOM   1691 H HA2  . GLY A 1 111 ? -51.32700 -31.67200 -5.48900  1.000 68.69819  ? 111 GLY A HA2  1 
ATOM   1692 H HA3  . GLY A 1 111 ? -50.67300 -33.09300 -5.37100  1.000 68.69819  ? 111 GLY A HA3  1 
ATOM   1693 N N    . ARG A 1 112 ? -48.84600 -31.64000 -3.56000  1.000 68.67217  ? 112 ARG A N    1 
ATOM   1694 C CA   . ARG A 1 112 ? -48.42300 -31.30700 -2.20800  1.000 63.80096  ? 112 ARG A CA   1 
ATOM   1695 C C    . ARG A 1 112 ? -48.45300 -29.79600 -2.00200  1.000 60.09377  ? 112 ARG A C    1 
ATOM   1696 O O    . ARG A 1 112 ? -48.20200 -29.02200 -2.92700  1.000 58.23676  ? 112 ARG A O    1 
ATOM   1697 C CB   . ARG A 1 112 ? -47.01700 -31.84200 -1.93700  1.000 61.80570  ? 112 ARG A CB   1 
ATOM   1698 C CG   . ARG A 1 112 ? -46.98200 -33.29200 -1.52400  1.000 74.96876  ? 112 ARG A CG   1 
ATOM   1699 C CD   . ARG A 1 112 ? -45.62400 -33.89800 -1.79800  1.000 79.21820  ? 112 ARG A CD   1 
ATOM   1700 N NE   . ARG A 1 112 ? -45.73100 -35.34500 -1.92300  1.000 86.71170  ? 112 ARG A NE   1 
ATOM   1701 C CZ   . ARG A 1 112 ? -45.45600 -36.20600 -0.95400  1.000 89.36571  ? 112 ARG A CZ   1 
ATOM   1702 N NH1  . ARG A 1 112 ? -44.99000 -35.80400 0.21900   1.000 83.52979  ? 112 ARG A NH1  1 
ATOM   1703 N NH2  . ARG A 1 112 ? -45.65100 -37.50400 -1.16700  1.000 90.87940  ? 112 ARG A NH2  1 
ATOM   1704 H H    . ARG A 1 112 ? -48.19900 -31.68300 -4.12200  1.000 76.56819  ? 112 ARG A H    1 
ATOM   1705 H HA   . ARG A 1 112 ? -49.03100 -31.71400 -1.57100  1.000 72.12819  ? 112 ARG A HA   1 
ATOM   1706 H HB2  . ARG A 1 112 ? -46.50500 -31.75900 -2.75400  1.000 70.86819  ? 112 ARG A HB2  1 
ATOM   1707 H HB3  . ARG A 1 112 ? -46.60700 -31.31700 -1.23200  1.000 70.86819  ? 112 ARG A HB3  1 
ATOM   1708 H HG2  . ARG A 1 112 ? -47.16100 -33.36100 -0.57300  1.000 86.11819  ? 112 ARG A HG2  1 
ATOM   1709 H HG3  . ARG A 1 112 ? -47.64600 -33.78700 -2.03000  1.000 86.11819  ? 112 ARG A HG3  1 
ATOM   1710 H HD2  . ARG A 1 112 ? -45.28200 -33.55400 -2.63700  1.000 91.82819  ? 112 ARG A HD2  1 
ATOM   1711 H HD3  . ARG A 1 112 ? -45.01600 -33.67600 -1.07700  1.000 91.82819  ? 112 ARG A HD3  1 
ATOM   1712 H HE   . ARG A 1 112 ? -45.99100 -35.66300 -2.67900  1.000 99.69819  ? 112 ARG A HE   1 
ATOM   1713 H HH11 . ARG A 1 112 ? -44.86000 -34.97000 0.37600   1.000 97.16819  ? 112 ARG A HH11 1 
ATOM   1714 H HH12 . ARG A 1 112 ? -44.81800 -36.38400 0.83000   1.000 97.16819  ? 112 ARG A HH12 1 
ATOM   1715 H HH21 . ARG A 1 112 ? -45.95100 -37.77500 -1.92600  1.000 103.45819 ? 112 ARG A HH21 1 
ATOM   1716 H HH22 . ARG A 1 112 ? -45.47200 -38.07300 -0.54800  1.000 103.45819 ? 112 ARG A HH22 1 
ATOM   1717 N N    . THR A 1 113 ? -48.76500 -29.38100 -0.77500  1.000 62.78254  ? 113 THR A N    1 
ATOM   1718 C CA   . THR A 1 113 ? -48.76000 -27.97000 -0.40000  1.000 53.59865  ? 113 THR A CA   1 
ATOM   1719 C C    . THR A 1 113 ? -47.37900 -27.59400 0.12300   1.000 49.02910  ? 113 THR A C    1 
ATOM   1720 O O    . THR A 1 113 ? -46.78400 -28.33000 0.91400   1.000 47.94451  ? 113 THR A O    1 
ATOM   1721 C CB   . THR A 1 113 ? -49.82700 -27.67400 0.65900   1.000 56.13983  ? 113 THR A CB   1 
ATOM   1722 O OG1  . THR A 1 113 ? -51.12000 -28.01400 0.14100   1.000 74.28530  ? 113 THR A OG1  1 
ATOM   1723 C CG2  . THR A 1 113 ? -49.83000 -26.20300 1.03300   1.000 57.96755  ? 113 THR A CG2  1 
ATOM   1724 H H    . THR A 1 113 ? -48.98700 -29.90800 -0.13200  1.000 73.27819  ? 113 THR A H    1 
ATOM   1725 H HA   . THR A 1 113 ? -48.94800 -27.42800 -1.18200  1.000 62.82819  ? 113 THR A HA   1 
ATOM   1726 H HB   . THR A 1 113 ? -49.64800 -28.19600 1.45700   1.000 65.31819  ? 113 THR A HB   1 
ATOM   1727 H HG1  . THR A 1 113 ? -51.71100 -27.85400 0.71600   1.000 85.59819  ? 113 THR A HG1  1 
ATOM   1728 H HG21 . THR A 1 113 ? -50.59600 -26.00600 1.59400   1.000 67.85819  ? 113 THR A HG21 1 
ATOM   1729 H HG22 . THR A 1 113 ? -49.02000 -25.97600 1.51500   1.000 67.85819  ? 113 THR A HG22 1 
ATOM   1730 H HG23 . THR A 1 113 ? -49.88300 -25.66500 0.22800   1.000 67.85819  ? 113 THR A HG23 1 
ATOM   1731 N N    . VAL A 1 114 ? -46.87600 -26.44000 -0.31800  1.000 50.99102  ? 114 VAL A N    1 
ATOM   1732 C CA   . VAL A 1 114 ? -45.49700 -26.03900 -0.05500  1.000 45.40962  ? 114 VAL A CA   1 
ATOM   1733 C C    . VAL A 1 114 ? -45.46400 -24.53500 0.16200   1.000 44.04667  ? 114 VAL A C    1 
ATOM   1734 O O    . VAL A 1 114 ? -45.89500 -23.76900 -0.70500  1.000 52.03626  ? 114 VAL A O    1 
ATOM   1735 C CB   . VAL A 1 114 ? -44.54900 -26.42800 -1.20700  1.000 50.74757  ? 114 VAL A CB   1 
ATOM   1736 C CG1  . VAL A 1 114 ? -43.23800 -25.62000 -1.14100  1.000 51.56049  ? 114 VAL A CG1  1 
ATOM   1737 C CG2  . VAL A 1 114 ? -44.24800 -27.92800 -1.18900  1.000 59.87687  ? 114 VAL A CG2  1 
ATOM   1738 H H    . VAL A 1 114 ? -47.32100 -25.86600 -0.77800  1.000 57.30819  ? 114 VAL A H    1 
ATOM   1739 H HA   . VAL A 1 114 ? -45.18500 -26.47000 0.75600   1.000 51.72819  ? 114 VAL A HA   1 
ATOM   1740 H HB   . VAL A 1 114 ? -44.98400 -26.22200 -2.04900  1.000 58.29819  ? 114 VAL A HB   1 
ATOM   1741 H HG11 . VAL A 1 114 ? -42.56400 -26.07300 -1.67200  1.000 60.12819  ? 114 VAL A HG11 1 
ATOM   1742 H HG12 . VAL A 1 114 ? -43.39100 -24.73100 -1.49700  1.000 60.12819  ? 114 VAL A HG12 1 
ATOM   1743 H HG13 . VAL A 1 114 ? -42.94600 -25.56500 -0.21800  1.000 60.12819  ? 114 VAL A HG13 1 
ATOM   1744 H HG21 . VAL A 1 114 ? -43.59300 -28.12800 -1.87600  1.000 69.25819  ? 114 VAL A HG21 1 
ATOM   1745 H HG22 . VAL A 1 114 ? -43.89800 -28.16700 -0.31700  1.000 69.25819  ? 114 VAL A HG22 1 
ATOM   1746 H HG23 . VAL A 1 114 ? -45.06900 -28.41600 -1.36100  1.000 69.25819  ? 114 VAL A HG23 1 
ATOM   1747 N N    . GLY A 1 115 ? -44.94700 -24.11200 1.31400   1.000 38.75095  ? 115 GLY A N    1 
ATOM   1748 C CA   . GLY A 1 115 ? -44.64500 -22.71200 1.53900   1.000 39.09570  ? 115 GLY A CA   1 
ATOM   1749 C C    . GLY A 1 115 ? -43.24000 -22.41100 1.05500   1.000 35.98440  ? 115 GLY A C    1 
ATOM   1750 O O    . GLY A 1 115 ? -42.30800 -23.17700 1.29200   1.000 44.02897  ? 115 GLY A O    1 
ATOM   1751 H H    . GLY A 1 115 ? -44.76300 -24.62300 1.98100   1.000 48.07819  ? 115 GLY A H    1 
ATOM   1752 H HA2  . GLY A 1 115 ? -45.27300 -22.15300 1.05600   1.000 48.50819  ? 115 GLY A HA2  1 
ATOM   1753 H HA3  . GLY A 1 115 ? -44.70400 -22.50800 2.48500   1.000 48.50819  ? 115 GLY A HA3  1 
ATOM   1754 N N    . GLY A 1 116 ? -43.09800 -21.29800 0.34900   1.000 41.54405  ? 116 GLY A N    1 
ATOM   1755 C CA   . GLY A 1 116 ? -41.80600 -20.93700 -0.18800  1.000 51.74725  ? 116 GLY A CA   1 
ATOM   1756 C C    . GLY A 1 116 ? -41.89400 -19.65600 -0.98300  1.000 40.54444  ? 116 GLY A C    1 
ATOM   1757 O O    . GLY A 1 116 ? -42.87800 -18.91900 -0.90600  1.000 46.06135  ? 116 GLY A O    1 
ATOM   1758 H H    . GLY A 1 116 ? -43.73000 -20.74300 0.17000   1.000 49.41819  ? 116 GLY A H    1 
ATOM   1759 H HA2  . GLY A 1 116 ? -41.18100 -20.81300 0.54000   1.000 61.96819  ? 116 GLY A HA2  1 
ATOM   1760 H HA3  . GLY A 1 116 ? -41.47900 -21.64400 -0.76600  1.000 61.96819  ? 116 GLY A HA3  1 
ATOM   1761 N N    . GLN A 1 117 ? -40.84800 -19.41200 -1.75800  1.000 33.15442  ? 117 GLN A N    1 
ATOM   1762 C CA   . GLN A 1 117 ? -40.72600 -18.19800 -2.54400  1.000 33.68666  ? 117 GLN A CA   1 
ATOM   1763 C C    . GLN A 1 117 ? -40.24200 -18.57700 -3.92800  1.000 37.84798  ? 117 GLN A C    1 
ATOM   1764 O O    . GLN A 1 117 ? -39.24300 -19.29100 -4.06100  1.000 39.49963  ? 117 GLN A O    1 
ATOM   1765 C CB   . GLN A 1 117 ? -39.75200 -17.21800 -1.88900  1.000 43.57478  ? 117 GLN A CB   1 
ATOM   1766 C CG   . GLN A 1 117 ? -39.50600 -15.95200 -2.67600  1.000 44.59740  ? 117 GLN A CG   1 
ATOM   1767 C CD   . GLN A 1 117 ? -38.71800 -14.91800 -1.88100  1.000 37.50145  ? 117 GLN A CD   1 
ATOM   1768 O OE1  . GLN A 1 117 ? -38.15200 -15.21500 -0.82600  1.000 38.35424  ? 117 GLN A OE1  1 
ATOM   1769 N NE2  . GLN A 1 117 ? -38.68600 -13.69400 -2.38500  1.000 47.66148  ? 117 GLN A NE2  1 
ATOM   1770 H H    . GLN A 1 117 ? -40.18100 -19.94800 -1.84600  1.000 45.09819  ? 117 GLN A H    1 
ATOM   1771 H HA   . GLN A 1 117 ? -41.59200 -17.76900 -2.62500  1.000 44.80819  ? 117 GLN A HA   1 
ATOM   1772 H HB2  . GLN A 1 117 ? -40.10600 -16.96100 -1.02300  1.000 56.68819  ? 117 GLN A HB2  1 
ATOM   1773 H HB3  . GLN A 1 117 ? -38.89700 -17.66200 -1.77300  1.000 56.68819  ? 117 GLN A HB3  1 
ATOM   1774 H HG2  . GLN A 1 117 ? -38.99800 -16.16700 -3.47400  1.000 56.79819  ? 117 GLN A HG2  1 
ATOM   1775 H HG3  . GLN A 1 117 ? -40.35900 -15.55900 -2.91900  1.000 56.79819  ? 117 GLN A HG3  1 
ATOM   1776 H HE21 . GLN A 1 117 ? -39.09300 -13.52200 -3.12300  1.000 58.97819  ? 117 GLN A HE21 1 
ATOM   1777 H HE22 . GLN A 1 117 ? -38.25600 -13.07200 -1.97600  1.000 58.97819  ? 117 GLN A HE22 1 
ATOM   1778 N N    . MET A 1 118 ? -40.94800 -18.11500 -4.95200  1.000 43.35207  ? 118 MET A N    1 
ATOM   1779 C CA   . MET A 1 118 ? -40.51900 -18.36400 -6.31600  1.000 43.85326  ? 118 MET A CA   1 
ATOM   1780 C C    . MET A 1 118 ? -39.41800 -17.38600 -6.67700  1.000 42.37777  ? 118 MET A C    1 
ATOM   1781 O O    . MET A 1 118 ? -39.31300 -16.29500 -6.11400  1.000 44.71261  ? 118 MET A O    1 
ATOM   1782 C CB   . MET A 1 118 ? -41.69300 -18.27600 -7.29700  1.000 50.33505  ? 118 MET A CB   1 
ATOM   1783 C CG   . MET A 1 118 ? -42.03000 -16.93700 -7.93900  1.000 53.58990  ? 118 MET A CG   1 
ATOM   1784 S SD   . MET A 1 118 ? -43.73200 -17.01500 -8.57000  1.000 84.20468  ? 118 MET A SD   1 
ATOM   1785 C CE   . MET A 1 118 ? -43.78200 -18.64800 -9.31500  1.000 73.54980  ? 118 MET A CE   1 
ATOM   1786 H H    . MET A 1 118 ? -41.67300 -17.65800 -4.88300  1.000 52.83819  ? 118 MET A H    1 
ATOM   1787 H HA   . MET A 1 118 ? -40.16200 -19.26400 -6.36900  1.000 52.64819  ? 118 MET A HA   1 
ATOM   1788 H HB2  . MET A 1 118 ? -41.50500 -18.89300 -8.02100  1.000 59.10819  ? 118 MET A HB2  1 
ATOM   1789 H HB3  . MET A 1 118 ? -42.49000 -18.57100 -6.83000  1.000 59.10819  ? 118 MET A HB3  1 
ATOM   1790 H HG2  . MET A 1 118 ? -41.97300 -16.23000 -7.27700  1.000 61.60819  ? 118 MET A HG2  1 
ATOM   1791 H HG3  . MET A 1 118 ? -41.42800 -16.76600 -8.68000  1.000 61.60819  ? 118 MET A HG3  1 
ATOM   1792 H HE1  . MET A 1 118 ? -44.56700 -18.71200 -9.88100  1.000 84.16819  ? 118 MET A HE1  1 
ATOM   1793 H HE2  . MET A 1 118 ? -42.98000 -18.77700 -9.84600  1.000 84.16819  ? 118 MET A HE2  1 
ATOM   1794 H HE3  . MET A 1 118 ? -43.82500 -19.31600 -8.61300  1.000 84.16819  ? 118 MET A HE3  1 
ATOM   1795 N N    . GLY A 1 119 ? -38.56800 -17.82300 -7.60000  1.000 40.53655  ? 119 GLY A N    1 
ATOM   1796 C CA   . GLY A 1 119 ? -37.42300 -17.06300 -8.04800  1.000 39.53493  ? 119 GLY A CA   1 
ATOM   1797 C C    . GLY A 1 119 ? -37.20600 -17.39500 -9.50300  1.000 36.78721  ? 119 GLY A C    1 
ATOM   1798 O O    . GLY A 1 119 ? -37.75600 -18.36400 -10.02700 1.000 49.26350  ? 119 GLY A O    1 
ATOM   1799 H H    . GLY A 1 119 ? -38.64300 -18.58500 -7.99100  1.000 52.46819  ? 119 GLY A H    1 
ATOM   1800 H HA2  . GLY A 1 119 ? -37.58900 -16.11200 -7.95400  1.000 50.57819  ? 119 GLY A HA2  1 
ATOM   1801 H HA3  . GLY A 1 119 ? -36.63400 -17.30600 -7.53900  1.000 50.57819  ? 119 GLY A HA3  1 
ATOM   1802 N N    . MET A 1 120 ? -36.40900 -16.55600 -10.15600 1.000 39.29902  ? 120 MET A N    1 
ATOM   1803 C CA   . MET A 1 120 ? -36.11800 -16.67100 -11.57700 1.000 43.53463  ? 120 MET A CA   1 
ATOM   1804 C C    . MET A 1 120 ? -34.60600 -16.67200 -11.72900 1.000 47.35919  ? 120 MET A C    1 
ATOM   1805 O O    . MET A 1 120 ? -33.94200 -15.71100 -11.33100 1.000 50.69203  ? 120 MET A O    1 
ATOM   1806 C CB   . MET A 1 120 ? -36.74100 -15.51700 -12.36300 1.000 53.58788  ? 120 MET A CB   1 
ATOM   1807 C CG   . MET A 1 120 ? -37.26200 -15.90500 -13.73100 1.000 65.91931  ? 120 MET A CG   1 
ATOM   1808 S SD   . MET A 1 120 ? -37.78000 -14.46600 -14.65800 1.000 107.85666 ? 120 MET A SD   1 
ATOM   1809 C CE   . MET A 1 120 ? -36.23200 -13.59100 -14.70400 1.000 70.80158  ? 120 MET A CE   1 
ATOM   1810 H H    . MET A 1 120 ? -36.01300 -15.89000 -9.78200  1.000 53.48819  ? 120 MET A H    1 
ATOM   1811 H HA   . MET A 1 120 ? -36.47800 -17.50500 -11.91800 1.000 56.89819  ? 120 MET A HA   1 
ATOM   1812 H HB2  . MET A 1 120 ? -37.48700 -15.16200 -11.85400 1.000 67.10819  ? 120 MET A HB2  1 
ATOM   1813 H HB3  . MET A 1 120 ? -36.06500 -14.83200 -12.47200 1.000 67.10819  ? 120 MET A HB3  1 
ATOM   1814 H HG2  . MET A 1 120 ? -36.55000 -16.33500 -14.22600 1.000 80.15819  ? 120 MET A HG2  1 
ATOM   1815 H HG3  . MET A 1 120 ? -38.02000 -16.50200 -13.63500 1.000 80.15819  ? 120 MET A HG3  1 
ATOM   1816 H HE1  . MET A 1 120 ? -36.24500 -12.97000 -15.44900 1.000 82.89819  ? 120 MET A HE1  1 
ATOM   1817 H HE2  . MET A 1 120 ? -36.11700 -13.10500 -13.87300 1.000 82.89819  ? 120 MET A HE2  1 
ATOM   1818 H HE3  . MET A 1 120 ? -35.51100 -14.23000 -14.82100 1.000 82.89819  ? 120 MET A HE3  1 
ATOM   1819 N N    . LEU A 1 121 ? -34.06000 -17.75900 -12.25500 1.000 49.76782  ? 121 LEU A N    1 
ATOM   1820 C CA   . LEU A 1 121 ? -32.62500 -17.81500 -12.48000 1.000 45.97904  ? 121 LEU A CA   1 
ATOM   1821 C C    . LEU A 1 121 ? -32.24300 -16.79800 -13.54000 1.000 59.95298  ? 121 LEU A C    1 
ATOM   1822 O O    . LEU A 1 121 ? -32.87200 -16.71900 -14.59900 1.000 70.49651  ? 121 LEU A O    1 
ATOM   1823 C CB   . LEU A 1 121 ? -32.20300 -19.21500 -12.90400 1.000 44.00280  ? 121 LEU A CB   1 
ATOM   1824 C CG   . LEU A 1 121 ? -32.20100 -20.18500 -11.72100 1.000 44.81583  ? 121 LEU A CG   1 
ATOM   1825 C CD1  . LEU A 1 121 ? -32.03100 -21.60600 -12.21400 1.000 51.41020  ? 121 LEU A CD1  1 
ATOM   1826 C CD2  . LEU A 1 121 ? -31.11000 -19.81400 -10.70700 1.000 43.90575  ? 121 LEU A CD2  1 
ATOM   1827 H H    . LEU A 1 121 ? -34.49000 -18.46700 -12.48700 1.000 65.57819  ? 121 LEU A H    1 
ATOM   1828 H HA   . LEU A 1 121 ? -32.16300 -17.58000 -11.66100 1.000 60.63819  ? 121 LEU A HA   1 
ATOM   1829 H HB2  . LEU A 1 121 ? -32.82500 -19.54900 -13.56900 1.000 58.36819  ? 121 LEU A HB2  1 
ATOM   1830 H HB3  . LEU A 1 121 ? -31.30600 -19.18100 -13.27100 1.000 58.36819  ? 121 LEU A HB3  1 
ATOM   1831 H HG   . LEU A 1 121 ? -33.05700 -20.12800 -11.26900 1.000 61.45819  ? 121 LEU A HG   1 
ATOM   1832 H HD11 . LEU A 1 121 ? -32.02800 -22.20600 -11.45200 1.000 69.21819  ? 121 LEU A HD11 1 
ATOM   1833 H HD12 . LEU A 1 121 ? -32.76800 -21.82500 -12.80500 1.000 69.21819  ? 121 LEU A HD12 1 
ATOM   1834 H HD13 . LEU A 1 121 ? -31.19000 -21.67500 -12.69300 1.000 69.21819  ? 121 LEU A HD13 1 
ATOM   1835 H HD21 . LEU A 1 121 ? -31.38800 -19.02800 -10.21300 1.000 61.36819  ? 121 LEU A HD21 1 
ATOM   1836 H HD22 . LEU A 1 121 ? -30.98200 -20.55800 -10.09800 1.000 61.36819  ? 121 LEU A HD22 1 
ATOM   1837 H HD23 . LEU A 1 121 ? -30.28500 -19.63300 -11.18400 1.000 61.36819  ? 121 LEU A HD23 1 
ATOM   1838 N N    . LEU A 1 122 ? -31.21700 -16.01400 -13.24800 1.000 65.01494  ? 122 LEU A N    1 
ATOM   1839 C CA   . LEU A 1 122 ? -30.73900 -14.99600 -14.16600 1.000 71.63495  ? 122 LEU A CA   1 
ATOM   1840 C C    . LEU A 1 122 ? -29.57000 -15.54600 -14.97100 1.000 80.82097  ? 122 LEU A C    1 
ATOM   1841 O O    . LEU A 1 122 ? -28.61600 -16.08800 -14.39900 1.000 66.33019  ? 122 LEU A O    1 
ATOM   1842 C CB   . LEU A 1 122 ? -30.32300 -13.74600 -13.38900 1.000 60.50243  ? 122 LEU A CB   1 
ATOM   1843 C CG   . LEU A 1 122 ? -31.40900 -13.07900 -12.53900 1.000 57.22222  ? 122 LEU A CG   1 
ATOM   1844 C CD1  . LEU A 1 122 ? -30.83000 -12.23300 -11.42400 1.000 55.82523  ? 122 LEU A CD1  1 
ATOM   1845 C CD2  . LEU A 1 122 ? -32.32300 -12.22500 -13.43100 1.000 62.15260  ? 122 LEU A CD2  1 
ATOM   1846 H H    . LEU A 1 122 ? -30.77400 -16.05300 -12.51200 1.000 78.15819  ? 122 LEU A H    1 
ATOM   1847 H HA   . LEU A 1 122 ? -31.44900 -14.75300 -14.78100 1.000 83.84819  ? 122 LEU A HA   1 
ATOM   1848 H HB2  . LEU A 1 122 ? -29.59800 -13.98700 -12.79200 1.000 70.47819  ? 122 LEU A HB2  1 
ATOM   1849 H HB3  . LEU A 1 122 ? -30.00800 -13.08400 -14.02500 1.000 70.47819  ? 122 LEU A HB3  1 
ATOM   1850 H HG   . LEU A 1 122 ? -31.95500 -13.76900 -12.13200 1.000 67.41819  ? 122 LEU A HG   1 
ATOM   1851 H HD11 . LEU A 1 122 ? -31.55300 -11.78600 -10.95800 1.000 66.23819  ? 122 LEU A HD11 1 
ATOM   1852 H HD12 . LEU A 1 122 ? -30.34600 -12.80800 -10.81100 1.000 66.23819  ? 122 LEU A HD12 1 
ATOM   1853 H HD13 . LEU A 1 122 ? -30.22800 -11.57600 -11.80700 1.000 66.23819  ? 122 LEU A HD13 1 
ATOM   1854 H HD21 . LEU A 1 122 ? -33.01700 -11.82700 -12.88200 1.000 71.46819  ? 122 LEU A HD21 1 
ATOM   1855 H HD22 . LEU A 1 122 ? -31.79300 -11.52900 -13.85100 1.000 71.46819  ? 122 LEU A HD22 1 
ATOM   1856 H HD23 . LEU A 1 122 ? -32.72200 -12.79300 -14.10900 1.000 71.46819  ? 122 LEU A HD23 1 
ATOM   1857 N N    . THR A 1 123 ? -29.65300 -15.39900 -16.29600 1.000 96.26647  ? 123 THR A N    1 
ATOM   1858 C CA   . THR A 1 123 ? -28.59000 -15.78000 -17.22100 1.000 103.37528 ? 123 THR A CA   1 
ATOM   1859 C C    . THR A 1 123 ? -27.93400 -17.09500 -16.80800 1.000 113.38571 ? 123 THR A C    1 
ATOM   1860 O O    . THR A 1 123 ? -28.52200 -18.17000 -16.94700 1.000 99.73678  ? 123 THR A O    1 
ATOM   1861 C CB   . THR A 1 123 ? -27.51400 -14.67900 -17.31800 1.000 106.50487 ? 123 THR A CB   1 
ATOM   1862 O OG1  . THR A 1 123 ? -26.42200 -15.14700 -18.11500 1.000 105.69665 ? 123 THR A OG1  1 
ATOM   1863 C CG2  . THR A 1 123 ? -27.00200 -14.30700 -15.94000 1.000 93.30262  ? 123 THR A CG2  1 
ATOM   1864 H H    . THR A 1 123 ? -30.34100 -15.06900 -16.69200 1.000 104.70819 ? 123 THR A H    1 
ATOM   1865 H HA   . THR A 1 123 ? -28.97200 -15.90200 -18.10400 1.000 111.53819 ? 123 THR A HA   1 
ATOM   1866 H HB   . THR A 1 123 ? -27.89700 -13.88800 -17.72700 1.000 113.82819 ? 123 THR A HB   1 
ATOM   1867 H HG1  . THR A 1 123 ? -25.98500 -15.72800 -17.69500 1.000 111.26819 ? 123 THR A HG1  1 
ATOM   1868 H HG21 . THR A 1 123 ? -27.67900 -13.81400 -15.45200 1.000 99.85819  ? 123 THR A HG21 1 
ATOM   1869 H HG22 . THR A 1 123 ? -26.76100 -15.10300 -15.44200 1.000 99.85819  ? 123 THR A HG22 1 
ATOM   1870 H HG23 . THR A 1 123 ? -26.21600 -13.74500 -16.02700 1.000 99.85819  ? 123 THR A HG23 1 
ATOM   1871 N N    . LEU A 1 132 ? -25.79800 -23.12800 -16.51700 1.000 97.01438  ? 132 LEU A N    1 
ATOM   1872 C CA   . LEU A 1 132 ? -26.74700 -24.06700 -17.09200 1.000 97.11707  ? 132 LEU A CA   1 
ATOM   1873 C C    . LEU A 1 132 ? -28.10900 -23.94500 -16.42100 1.000 93.87820  ? 132 LEU A C    1 
ATOM   1874 O O    . LEU A 1 132 ? -28.99700 -23.25900 -16.91500 1.000 98.48443  ? 132 LEU A O    1 
ATOM   1875 C CB   . LEU A 1 132 ? -26.22000 -25.48900 -16.95900 1.000 99.77442  ? 132 LEU A CB   1 
ATOM   1876 C CG   . LEU A 1 132 ? -27.07600 -26.56600 -17.61600 1.000 106.02839 ? 132 LEU A CG   1 
ATOM   1877 C CD1  . LEU A 1 132 ? -26.21700 -27.46500 -18.45900 1.000 103.58819 ? 132 LEU A CD1  1 
ATOM   1878 C CD2  . LEU A 1 132 ? -27.79200 -27.34900 -16.53700 1.000 97.99418  ? 132 LEU A CD2  1 
ATOM   1879 H HA   . LEU A 1 132 ? -26.85600 -23.87200 -18.03600 1.000 126.37819 ? 132 LEU A HA   1 
ATOM   1880 H HB2  . LEU A 1 132 ? -25.34800 -25.52400 -17.38200 1.000 129.85819 ? 132 LEU A HB2  1 
ATOM   1881 H HB3  . LEU A 1 132 ? -26.12300 -25.70200 -16.01900 1.000 129.85819 ? 132 LEU A HB3  1 
ATOM   1882 H HG   . LEU A 1 132 ? -27.74000 -26.14900 -18.18700 1.000 136.43819 ? 132 LEU A HG   1 
ATOM   1883 H HD11 . LEU A 1 132 ? -26.77300 -28.15700 -18.84900 1.000 131.55819 ? 132 LEU A HD11 1 
ATOM   1884 H HD12 . LEU A 1 132 ? -25.80300 -26.93900 -19.16100 1.000 131.55819 ? 132 LEU A HD12 1 
ATOM   1885 H HD13 . LEU A 1 132 ? -25.53400 -27.86600 -17.89800 1.000 131.55819 ? 132 LEU A HD13 1 
ATOM   1886 H HD21 . LEU A 1 132 ? -28.09400 -28.19000 -16.91500 1.000 129.01819 ? 132 LEU A HD21 1 
ATOM   1887 H HD22 . LEU A 1 132 ? -27.18400 -27.52300 -15.80200 1.000 129.01819 ? 132 LEU A HD22 1 
ATOM   1888 H HD23 . LEU A 1 132 ? -28.55600 -26.84200 -16.22600 1.000 129.01819 ? 132 LEU A HD23 1 
ATOM   1889 N N    . GLY A 1 133 ? -28.27100 -24.60900 -15.28600 1.000 97.36287  ? 133 GLY A N    1 
ATOM   1890 C CA   . GLY A 1 133 ? -29.55200 -24.59900 -14.61100 1.000 76.63218  ? 133 GLY A CA   1 
ATOM   1891 C C    . GLY A 1 133 ? -29.49800 -25.50500 -13.40300 1.000 71.36747  ? 133 GLY A C    1 
ATOM   1892 O O    . GLY A 1 133 ? -28.42200 -25.91800 -12.97200 1.000 74.69831  ? 133 GLY A O    1 
ATOM   1893 H H    . GLY A 1 133 ? -27.66200 -25.06500 -14.88600 1.000 108.10819 ? 133 GLY A H    1 
ATOM   1894 H HA2  . GLY A 1 133 ? -29.76800 -23.69900 -14.32200 1.000 84.64819  ? 133 GLY A HA2  1 
ATOM   1895 H HA3  . GLY A 1 133 ? -30.24600 -24.91300 -15.21100 1.000 84.64819  ? 133 GLY A HA3  1 
ATOM   1896 N N    . THR A 1 134 ? -30.66600 -25.81400 -12.85400 1.000 65.45103  ? 134 THR A N    1 
ATOM   1897 C CA   . THR A 1 134 ? -30.73800 -26.72600 -11.72100 1.000 52.61852  ? 134 THR A CA   1 
ATOM   1898 C C    . THR A 1 134 ? -31.17100 -28.11700 -12.17700 1.000 51.28021  ? 134 THR A C    1 
ATOM   1899 O O    . THR A 1 134 ? -31.84100 -28.28200 -13.19900 1.000 52.14996  ? 134 THR A O    1 
ATOM   1900 C CB   . THR A 1 134 ? -31.71100 -26.21500 -10.65900 1.000 44.08622  ? 134 THR A CB   1 
ATOM   1901 O OG1  . THR A 1 134 ? -32.93600 -25.82600 -11.28500 1.000 52.23259  ? 134 THR A OG1  1 
ATOM   1902 C CG2  . THR A 1 134 ? -31.12700 -25.03700 -9.90800  1.000 42.66496  ? 134 THR A CG2  1 
ATOM   1903 H H    . THR A 1 134 ? -31.42700 -25.51100 -13.11700 1.000 78.73819  ? 134 THR A H    1 
ATOM   1904 H HA   . THR A 1 134 ? -29.86200 -26.80500 -11.31300 1.000 65.02819  ? 134 THR A HA   1 
ATOM   1905 H HB   . THR A 1 134 ? -31.88900 -26.92400 -10.02100 1.000 56.27819  ? 134 THR A HB   1 
ATOM   1906 H HG1  . THR A 1 134 ? -33.47700 -25.54400 -10.70800 1.000 65.20819  ? 134 THR A HG1  1 
ATOM   1907 H HG21 . THR A 1 134 ? -31.20600 -25.18300 -8.95300  1.000 55.38819  ? 134 THR A HG21 1 
ATOM   1908 H HG22 . THR A 1 134 ? -30.19200 -24.92600 -10.13800 1.000 55.38819  ? 134 THR A HG22 1 
ATOM   1909 H HG23 . THR A 1 134 ? -31.60500 -24.22600 -10.14300 1.000 55.38819  ? 134 THR A HG23 1 
ATOM   1910 N N    . THR A 1 135 ? -30.78900 -29.13100 -11.38400 1.000 58.42948  ? 135 THR A N    1 
ATOM   1911 C CA   . THR A 1 135 ? -31.17700 -30.50300 -11.71600 1.000 57.58794  ? 135 THR A CA   1 
ATOM   1912 C C    . THR A 1 135 ? -31.75800 -31.25800 -10.52200 1.000 56.36748  ? 135 THR A C    1 
ATOM   1913 O O    . THR A 1 135 ? -31.90800 -30.67200 -9.44400  1.000 55.78631  ? 135 THR A O    1 
ATOM   1914 C CB   . THR A 1 135 ? -29.97500 -31.27800 -12.26500 1.000 61.07687  ? 135 THR A CB   1 
ATOM   1915 O OG1  . THR A 1 135 ? -29.02600 -31.50900 -11.21200 1.000 59.33892  ? 135 THR A OG1  1 
ATOM   1916 C CG2  . THR A 1 135 ? -29.30100 -30.49800 -13.37800 1.000 66.30312  ? 135 THR A CG2  1 
ATOM   1917 H H    . THR A 1 135 ? -30.31800 -29.05100 -10.66900 1.000 61.54819  ? 135 THR A H    1 
ATOM   1918 H HA   . THR A 1 135 ? -31.85600 -30.48300 -12.40800 1.000 59.77819  ? 135 THR A HA   1 
ATOM   1919 H HB   . THR A 1 135 ? -30.24800 -32.12200 -12.64200 1.000 62.89819  ? 135 THR A HB   1 
ATOM   1920 H HG1  . THR A 1 135 ? -28.36500 -31.93400 -11.50900 1.000 62.18819  ? 135 THR A HG1  1 
ATOM   1921 H HG21 . THR A 1 135 ? -28.63000 -31.05000 -13.80900 1.000 67.60819  ? 135 THR A HG21 1 
ATOM   1922 H HG22 . THR A 1 135 ? -29.95900 -30.22800 -14.03800 1.000 67.60819  ? 135 THR A HG22 1 
ATOM   1923 H HG23 . THR A 1 135 ? -28.87300 -29.70600 -13.01800 1.000 67.60819  ? 135 THR A HG23 1 
ATOM   1924 N N    . PRO A 1 136 ? -32.10300 -32.55000 -10.66700 1.000 44.55094  ? 136 PRO A N    1 
ATOM   1925 C CA   . PRO A 1 136 ? -32.73800 -33.26900 -9.54300  1.000 49.92361  ? 136 PRO A CA   1 
ATOM   1926 C C    . PRO A 1 136 ? -31.85800 -33.57000 -8.33300  1.000 55.86252  ? 136 PRO A C    1 
ATOM   1927 O O    . PRO A 1 136 ? -32.41000 -33.79700 -7.24500  1.000 52.49068  ? 136 PRO A O    1 
ATOM   1928 C CB   . PRO A 1 136 ? -33.21500 -34.58300 -10.18800 1.000 46.32721  ? 136 PRO A CB   1 
ATOM   1929 C CG   . PRO A 1 136 ? -33.43500 -34.23700 -11.60000 1.000 45.84925  ? 136 PRO A CG   1 
ATOM   1930 C CD   . PRO A 1 136 ? -32.34000 -33.24900 -11.94500 1.000 47.59992  ? 136 PRO A CD   1 
ATOM   1931 H HA   . PRO A 1 136 ? -33.51600 -32.77500 -9.24100  1.000 58.71819  ? 136 PRO A HA   1 
ATOM   1932 H HB2  . PRO A 1 136 ? -32.52700 -35.26100 -10.10200 1.000 52.81819  ? 136 PRO A HB2  1 
ATOM   1933 H HB3  . PRO A 1 136 ? -34.04100 -34.87400 -9.77100  1.000 52.81819  ? 136 PRO A HB3  1 
ATOM   1934 H HG2  . PRO A 1 136 ? -33.36100 -35.03500 -12.14700 1.000 50.42819  ? 136 PRO A HG2  1 
ATOM   1935 H HG3  . PRO A 1 136 ? -34.30900 -33.83000 -11.70400 1.000 50.42819  ? 136 PRO A HG3  1 
ATOM   1936 H HD2  . PRO A 1 136 ? -31.54600 -33.73000 -12.22400 1.000 52.66819  ? 136 PRO A HD2  1 
ATOM   1937 H HD3  . PRO A 1 136 ? -32.64400 -32.62900 -12.62600 1.000 52.66819  ? 136 PRO A HD3  1 
ATOM   1938 N N    . GLY A 1 137 ? -30.53500 -33.62200 -8.46900  1.000 53.21770  ? 137 GLY A N    1 
ATOM   1939 C CA   . GLY A 1 137 ? -29.71600 -33.82200 -7.28600  1.000 56.80619  ? 137 GLY A CA   1 
ATOM   1940 C C    . GLY A 1 137 ? -29.65400 -32.62500 -6.36100  1.000 49.77941  ? 137 GLY A C    1 
ATOM   1941 O O    . GLY A 1 137 ? -29.16700 -32.76500 -5.23200  1.000 48.72028  ? 137 GLY A O    1 
ATOM   1942 H H    . GLY A 1 137 ? -30.10300 -33.54700 -9.20900  1.000 56.24819  ? 137 GLY A H    1 
ATOM   1943 H HA2  . GLY A 1 137 ? -30.06500 -34.57400 -6.78200  1.000 61.76819  ? 137 GLY A HA2  1 
ATOM   1944 H HA3  . GLY A 1 137 ? -28.81100 -34.03700 -7.56100  1.000 61.76819  ? 137 GLY A HA3  1 
ATOM   1945 N N    . ASP A 1 138 ? -30.18000 -31.47500 -6.79700  1.000 42.62600  ? 138 ASP A N    1 
ATOM   1946 C CA   . ASP A 1 138 ? -29.87300 -30.18500 -6.19400  1.000 33.41543  ? 138 ASP A CA   1 
ATOM   1947 C C    . ASP A 1 138 ? -30.81400 -29.79700 -5.05900  1.000 35.68083  ? 138 ASP A C    1 
ATOM   1948 O O    . ASP A 1 138 ? -30.49700 -28.86000 -4.31600  1.000 34.33038  ? 138 ASP A O    1 
ATOM   1949 C CB   . ASP A 1 138 ? -29.89200 -29.08200 -7.26300  1.000 35.29626  ? 138 ASP A CB   1 
ATOM   1950 C CG   . ASP A 1 138 ? -28.82700 -29.26800 -8.30900  1.000 41.22972  ? 138 ASP A CG   1 
ATOM   1951 O OD1  . ASP A 1 138 ? -27.82900 -29.97900 -8.03500  1.000 42.53780  ? 138 ASP A OD1  1 
ATOM   1952 O OD2  . ASP A 1 138 ? -29.00700 -28.69900 -9.40400  1.000 41.18852  ? 138 ASP A OD2  1 
ATOM   1953 H H    . ASP A 1 138 ? -30.72900 -31.42000 -7.45600  1.000 55.42819  ? 138 ASP A H    1 
ATOM   1954 H HA   . ASP A 1 138 ? -28.97600 -30.22300 -5.82800  1.000 45.22819  ? 138 ASP A HA   1 
ATOM   1955 H HB2  . ASP A 1 138 ? -30.75400 -29.08800 -7.70800  1.000 46.59819  ? 138 ASP A HB2  1 
ATOM   1956 H HB3  . ASP A 1 138 ? -29.74500 -28.22400 -6.83500  1.000 46.59819  ? 138 ASP A HB3  1 
ATOM   1957 N N    . CYS A 1 139 ? -31.95100 -30.48100 -4.89700  1.000 39.65000  ? 139 CYS A N    1 
ATOM   1958 C CA   . CYS A 1 139 ? -32.82600 -30.20200 -3.76200  1.000 31.49598  ? 139 CYS A CA   1 
ATOM   1959 C C    . CYS A 1 139 ? -32.03200 -30.26600 -2.46500  1.000 27.67571  ? 139 CYS A C    1 
ATOM   1960 O O    . CYS A 1 139 ? -31.24000 -31.18700 -2.25400  1.000 26.12082  ? 139 CYS A O    1 
ATOM   1961 C CB   . CYS A 1 139 ? -33.99000 -31.18600 -3.73900  1.000 30.69052  ? 139 CYS A CB   1 
ATOM   1962 S SG   . CYS A 1 139 ? -35.16900 -30.84600 -5.04700  1.000 43.95175  ? 139 CYS A SG   1 
ATOM   1963 H H    . CYS A 1 139 ? -32.23200 -31.10100 -5.42300  1.000 57.87819  ? 139 CYS A H    1 
ATOM   1964 H HA   . CYS A 1 139 ? -33.18800 -29.30700 -3.85100  1.000 48.95819  ? 139 CYS A HA   1 
ATOM   1965 H HB2  . CYS A 1 139 ? -33.64600 -32.08400 -3.86200  1.000 47.64819  ? 139 CYS A HB2  1 
ATOM   1966 H HB3  . CYS A 1 139 ? -34.45100 -31.11600 -2.88900  1.000 47.64819  ? 139 CYS A HB3  1 
ATOM   1967 N N    . GLY A 1 140 ? -32.21600 -29.25600 -1.61700  1.000 34.42628  ? 140 GLY A N    1 
ATOM   1968 C CA   . GLY A 1 140 ? -31.52000 -29.14800 -0.34900  1.000 34.94053  ? 140 GLY A CA   1 
ATOM   1969 C C    . GLY A 1 140 ? -30.52700 -28.00500 -0.27500  1.000 39.84296  ? 140 GLY A C    1 
ATOM   1970 O O    . GLY A 1 140 ? -30.24200 -27.51700 0.82800   1.000 33.06655  ? 140 GLY A O    1 
ATOM   1971 H H    . GLY A 1 140 ? -32.75700 -28.60400 -1.76400  1.000 42.20819  ? 140 GLY A H    1 
ATOM   1972 H HA2  . GLY A 1 140 ? -32.17000 -29.03000 0.36200   1.000 43.39819  ? 140 GLY A HA2  1 
ATOM   1973 H HA3  . GLY A 1 140 ? -31.04100 -29.97300 -0.18700  1.000 43.39819  ? 140 GLY A HA3  1 
ATOM   1974 N N    . CYS A 1 141 ? -29.98800 -27.55000 -1.41400  1.000 38.43887  ? 141 CYS A N    1 
ATOM   1975 C CA   . CYS A 1 141 ? -29.00400 -26.47700 -1.39400  1.000 34.87003  ? 141 CYS A CA   1 
ATOM   1976 C C    . CYS A 1 141 ? -29.64200 -25.15200 -0.98400  1.000 37.24687  ? 141 CYS A C    1 
ATOM   1977 O O    . CYS A 1 141 ? -30.80400 -24.88600 -1.29800  1.000 39.17215  ? 141 CYS A O    1 
ATOM   1978 C CB   . CYS A 1 141 ? -28.34700 -26.32600 -2.75900  1.000 44.79955  ? 141 CYS A CB   1 
ATOM   1979 S SG   . CYS A 1 141 ? -27.35900 -27.77100 -3.20700  1.000 38.48993  ? 141 CYS A SG   1 
ATOM   1980 H H    . CYS A 1 141 ? -30.17700 -27.84600 -2.19900  1.000 46.20819  ? 141 CYS A H    1 
ATOM   1981 H HA   . CYS A 1 141 ? -28.31800 -26.71600 -0.75500  1.000 41.68819  ? 141 CYS A HA   1 
ATOM   1982 H HB2  . CYS A 1 141 ? -29.03700 -26.21300 -3.43200  1.000 52.74819  ? 141 CYS A HB2  1 
ATOM   1983 H HB3  . CYS A 1 141 ? -27.76600 -25.55100 -2.74600  1.000 52.74819  ? 141 CYS A HB3  1 
ATOM   1984 H HG   . CYS A 1 141 ? -28.08700 -28.72300 -3.26200  1.000 44.82819  ? 141 CYS A HG   1 
ATOM   1985 N N    . PRO A 1 142 ? -28.89300 -24.30200 -0.29000  1.000 38.42318  ? 142 PRO A N    1 
ATOM   1986 C CA   . PRO A 1 142 ? -29.47200 -23.09100 0.29700   1.000 36.74398  ? 142 PRO A CA   1 
ATOM   1987 C C    . PRO A 1 142 ? -29.47100 -21.88500 -0.63700  1.000 40.43596  ? 142 PRO A C    1 
ATOM   1988 O O    . PRO A 1 142 ? -28.63700 -21.75300 -1.53700  1.000 38.02252  ? 142 PRO A O    1 
ATOM   1989 C CB   . PRO A 1 142 ? -28.55200 -22.84100 1.50000   1.000 33.87247  ? 142 PRO A CB   1 
ATOM   1990 C CG   . PRO A 1 142 ? -27.21800 -23.32300 1.00700   1.000 34.47119  ? 142 PRO A CG   1 
ATOM   1991 C CD   . PRO A 1 142 ? -27.46700 -24.45800 0.04900   1.000 40.99557  ? 142 PRO A CD   1 
ATOM   1992 H HA   . PRO A 1 142 ? -30.37500 -23.26100 0.60900   1.000 44.85819  ? 142 PRO A HA   1 
ATOM   1993 H HB2  . PRO A 1 142 ? -28.52600 -21.89400 1.70900   1.000 41.35819  ? 142 PRO A HB2  1 
ATOM   1994 H HB3  . PRO A 1 142 ? -28.85200 -23.36100 2.26200   1.000 41.35819  ? 142 PRO A HB3  1 
ATOM   1995 H HG2  . PRO A 1 142 ? -26.76000 -22.59600 0.55700   1.000 41.79819  ? 142 PRO A HG2  1 
ATOM   1996 H HG3  . PRO A 1 142 ? -26.69500 -23.63700 1.75300   1.000 41.79819  ? 142 PRO A HG3  1 
ATOM   1997 H HD2  . PRO A 1 142 ? -26.91600 -24.36200 -0.74300  1.000 49.85819  ? 142 PRO A HD2  1 
ATOM   1998 H HD3  . PRO A 1 142 ? -27.30900 -25.30500 0.49400   1.000 49.85819  ? 142 PRO A HD3  1 
ATOM   1999 N N    . TYR A 1 143 ? -30.45600 -21.00800 -0.41000  1.000 35.70530  ? 143 TYR A N    1 
ATOM   2000 C CA   . TYR A 1 143 ? -30.52100 -19.68100 -1.01300  1.000 31.58398  ? 143 TYR A CA   1 
ATOM   2001 C C    . TYR A 1 143 ? -29.96400 -18.69900 0.01100   1.000 30.83770  ? 143 TYR A C    1 
ATOM   2002 O O    . TYR A 1 143 ? -30.35800 -18.74000 1.17900   1.000 32.05362  ? 143 TYR A O    1 
ATOM   2003 C CB   . TYR A 1 143 ? -31.95800 -19.31600 -1.38900  1.000 37.11647  ? 143 TYR A CB   1 
ATOM   2004 C CG   . TYR A 1 143 ? -32.51200 -20.04600 -2.59300  1.000 33.13121  ? 143 TYR A CG   1 
ATOM   2005 C CD1  . TYR A 1 143 ? -32.83500 -21.39400 -2.53200  1.000 36.01922  ? 143 TYR A CD1  1 
ATOM   2006 C CD2  . TYR A 1 143 ? -32.73500 -19.37500 -3.78100  1.000 33.25843  ? 143 TYR A CD2  1 
ATOM   2007 C CE1  . TYR A 1 143 ? -33.35600 -22.05500 -3.63400  1.000 40.03164  ? 143 TYR A CE1  1 
ATOM   2008 C CE2  . TYR A 1 143 ? -33.24200 -20.02500 -4.88500  1.000 39.89046  ? 143 TYR A CE2  1 
ATOM   2009 C CZ   . TYR A 1 143 ? -33.55100 -21.36400 -4.80700  1.000 38.40294  ? 143 TYR A CZ   1 
ATOM   2010 O OH   . TYR A 1 143 ? -34.06300 -22.00800 -5.91000  1.000 37.63491  ? 143 TYR A OH   1 
ATOM   2011 H H    . TYR A 1 143 ? -31.12100 -21.17100 0.11100   1.000 48.77819  ? 143 TYR A H    1 
ATOM   2012 H HA   . TYR A 1 143 ? -29.97000 -19.65200 -1.81000  1.000 42.93819  ? 143 TYR A HA   1 
ATOM   2013 H HB2  . TYR A 1 143 ? -32.53400 -19.51700 -0.63500  1.000 49.44819  ? 143 TYR A HB2  1 
ATOM   2014 H HB3  . TYR A 1 143 ? -31.99400 -18.36600 -1.58100  1.000 49.44819  ? 143 TYR A HB3  1 
ATOM   2015 H HD1  . TYR A 1 143 ? -32.70000 -21.86200 -1.74000  1.000 48.73819  ? 143 TYR A HD1  1 
ATOM   2016 H HD2  . TYR A 1 143 ? -32.52500 -18.47100 -3.84100  1.000 43.73819  ? 143 TYR A HD2  1 
ATOM   2017 H HE1  . TYR A 1 143 ? -33.56000 -22.95900 -3.58400  1.000 53.19819  ? 143 TYR A HE1  1 
ATOM   2018 H HE2  . TYR A 1 143 ? -33.38100 -19.55900 -5.67800  1.000 51.32819  ? 143 TYR A HE2  1 
ATOM   2019 H HH   . TYR A 1 143 ? -34.57400 -22.62700 -5.66600  1.000 48.65819  ? 143 TYR A HH   1 
ATOM   2020 N N    . ILE A 1 144 ? -29.03800 -17.84100 -0.41300  1.000 44.59224  ? 144 ILE A N    1 
ATOM   2021 C CA   . ILE A 1 144 ? -28.35700 -16.89700 0.46900   1.000 40.80351  ? 144 ILE A CA   1 
ATOM   2022 C C    . ILE A 1 144 ? -28.22800 -15.56300 -0.25900  1.000 44.67198  ? 144 ILE A C    1 
ATOM   2023 O O    . ILE A 1 144 ? -27.96700 -15.52900 -1.46600  1.000 50.55113  ? 144 ILE A O    1 
ATOM   2024 C CB   . ILE A 1 144 ? -26.96600 -17.42700 0.89700   1.000 42.39330  ? 144 ILE A CB   1 
ATOM   2025 C CG1  . ILE A 1 144 ? -27.10100 -18.76500 1.64500   1.000 43.35241  ? 144 ILE A CG1  1 
ATOM   2026 C CG2  . ILE A 1 144 ? -26.22300 -16.40800 1.75500   1.000 53.10776  ? 144 ILE A CG2  1 
ATOM   2027 C CD1  . ILE A 1 144 ? -25.75700 -19.37100 2.19800   1.000 48.68721  ? 144 ILE A CD1  1 
ATOM   2028 H H    . ILE A 1 144 ? -28.78100 -17.78600 -1.23200  1.000 52.49819  ? 144 ILE A H    1 
ATOM   2029 H HA   . ILE A 1 144 ? -28.89100 -16.76100 1.26600   1.000 47.19819  ? 144 ILE A HA   1 
ATOM   2030 H HB   . ILE A 1 144 ? -26.44400 -17.58200 0.09500   1.000 49.08819  ? 144 ILE A HB   1 
ATOM   2031 H HG12 . ILE A 1 144 ? -27.69500 -18.63600 2.40100   1.000 51.40819  ? 144 ILE A HG12 1 
ATOM   2032 H HG13 . ILE A 1 144 ? -27.48500 -19.41800 1.04000   1.000 51.40819  ? 144 ILE A HG13 1 
ATOM   2033 H HG21 . ILE A 1 144 ? -25.37100 -16.78100 2.03000   1.000 60.84819  ? 144 ILE A HG21 1 
ATOM   2034 H HG22 . ILE A 1 144 ? -26.07100 -15.60300 1.23700   1.000 60.84819  ? 144 ILE A HG22 1 
ATOM   2035 H HG23 . ILE A 1 144 ? -26.76100 -16.20200 2.53500   1.000 60.84819  ? 144 ILE A HG23 1 
ATOM   2036 H HD11 . ILE A 1 144 ? -25.52600 -18.92100 3.02500   1.000 57.71819  ? 144 ILE A HD11 1 
ATOM   2037 H HD12 . ILE A 1 144 ? -25.88200 -20.31900 2.36100   1.000 57.71819  ? 144 ILE A HD12 1 
ATOM   2038 H HD13 . ILE A 1 144 ? -25.05700 -19.23800 1.54000   1.000 57.71819  ? 144 ILE A HD13 1 
ATOM   2039 N N    . TYR A 1 145 ? -28.42700 -14.46500 0.47300   1.000 42.32816  ? 145 TYR A N    1 
ATOM   2040 C CA   . TYR A 1 145 ? -28.17800 -13.11700 -0.03000  1.000 41.22569  ? 145 TYR A CA   1 
ATOM   2041 C C    . TYR A 1 145 ? -27.46900 -12.33000 1.07100   1.000 46.83504  ? 145 TYR A C    1 
ATOM   2042 O O    . TYR A 1 145 ? -27.63500 -12.61600 2.26200   1.000 57.54970  ? 145 TYR A O    1 
ATOM   2043 C CB   . TYR A 1 145 ? -29.49300 -12.45200 -0.52600  1.000 46.00743  ? 145 TYR A CB   1 
ATOM   2044 C CG   . TYR A 1 145 ? -30.41300 -11.84900 0.52000   1.000 42.12227  ? 145 TYR A CG   1 
ATOM   2045 C CD1  . TYR A 1 145 ? -31.27900 -12.63600 1.26400   1.000 36.87268  ? 145 TYR A CD1  1 
ATOM   2046 C CD2  . TYR A 1 145 ? -30.42700 -10.48200 0.74500   1.000 45.50117  ? 145 TYR A CD2  1 
ATOM   2047 C CE1  . TYR A 1 145 ? -32.11900 -12.07400 2.21400   1.000 39.10797  ? 145 TYR A CE1  1 
ATOM   2048 C CE2  . TYR A 1 145 ? -31.26000 -9.91700  1.68800   1.000 45.22907  ? 145 TYR A CE2  1 
ATOM   2049 C CZ   . TYR A 1 145 ? -32.10600 -10.71200 2.41400   1.000 39.24757  ? 145 TYR A CZ   1 
ATOM   2050 O OH   . TYR A 1 145 ? -32.93300 -10.13400 3.34900   1.000 51.68995  ? 145 TYR A OH   1 
ATOM   2051 H H    . TYR A 1 145 ? -28.71300 -14.47900 1.28400   1.000 54.32819  ? 145 TYR A H    1 
ATOM   2052 H HA   . TYR A 1 145 ? -27.57400 -13.17300 -0.78700  1.000 51.40819  ? 145 TYR A HA   1 
ATOM   2053 H HB2  . TYR A 1 145 ? -29.25500 -11.73900 -1.13900  1.000 56.81819  ? 145 TYR A HB2  1 
ATOM   2054 H HB3  . TYR A 1 145 ? -30.00700 -13.12300 -1.00300  1.000 56.81819  ? 145 TYR A HB3  1 
ATOM   2055 H HD1  . TYR A 1 145 ? -31.29100 -13.55600 1.13000   1.000 46.89819  ? 145 TYR A HD1  1 
ATOM   2056 H HD2  . TYR A 1 145 ? -29.85700 -9.93400  0.25500   1.000 54.45819  ? 145 TYR A HD2  1 
ATOM   2057 H HE1  . TYR A 1 145 ? -32.69300 -12.61400 2.70800   1.000 49.19819  ? 145 TYR A HE1  1 
ATOM   2058 H HE2  . TYR A 1 145 ? -31.25200 -8.99700  1.82500   1.000 53.73819  ? 145 TYR A HE2  1 
ATOM   2059 H HH   . TYR A 1 145 ? -32.81700 -9.30200  3.36000   1.000 62.10819  ? 145 TYR A HH   1 
ATOM   2060 N N    . LYS A 1 146 ? -26.61200 -11.38600 0.66500   1.000 45.07885  ? 146 LYS A N    1 
ATOM   2061 C CA   . LYS A 1 146 ? -25.86800 -10.54900 1.60200   1.000 52.44665  ? 146 LYS A CA   1 
ATOM   2062 C C    . LYS A 1 146 ? -26.66900 -9.28800  1.88000   1.000 55.27394  ? 146 LYS A C    1 
ATOM   2063 O O    . LYS A 1 146 ? -27.05200 -8.58100  0.94600   1.000 49.74020  ? 146 LYS A O    1 
ATOM   2064 C CB   . LYS A 1 146 ? -24.48900 -10.15100 1.06900   1.000 53.66599  ? 146 LYS A CB   1 
ATOM   2065 C CG   . LYS A 1 146 ? -23.61000 -9.47100  2.12700   1.000 71.06935  ? 146 LYS A CG   1 
ATOM   2066 C CD   . LYS A 1 146 ? -22.12600 -9.45300  1.75800   1.000 79.56092  ? 146 LYS A CD   1 
ATOM   2067 C CE   . LYS A 1 146 ? -21.68700 -8.13000  1.12600   1.000 82.46138  ? 146 LYS A CE   1 
ATOM   2068 N NZ   . LYS A 1 146 ? -20.26200 -8.19300  0.67800   1.000 73.29567  ? 146 LYS A NZ   1 
ATOM   2069 H H    . LYS A 1 146 ? -26.44500 -11.21200 -0.16000  1.000 61.70819  ? 146 LYS A H    1 
ATOM   2070 H HA   . LYS A 1 146 ? -25.74700 -11.02700 2.43700   1.000 69.16819  ? 146 LYS A HA   1 
ATOM   2071 H HB2  . LYS A 1 146 ? -24.02900 -10.94800 0.76300   1.000 69.21819  ? 146 LYS A HB2  1 
ATOM   2072 H HB3  . LYS A 1 146 ? -24.60300 -9.53100  0.33200   1.000 69.21819  ? 146 LYS A HB3  1 
ATOM   2073 H HG2  . LYS A 1 146 ? -23.90200 -8.55200  2.23500   1.000 88.60819  ? 146 LYS A HG2  1 
ATOM   2074 H HG3  . LYS A 1 146 ? -23.70300 -9.94800  2.96700   1.000 88.60819  ? 146 LYS A HG3  1 
ATOM   2075 H HD2  . LYS A 1 146 ? -21.60000 -9.59000  2.56100   1.000 97.65819  ? 146 LYS A HD2  1 
ATOM   2076 H HD3  . LYS A 1 146 ? -21.94800 -10.16300 1.12100   1.000 97.65819  ? 146 LYS A HD3  1 
ATOM   2077 H HE2  . LYS A 1 146 ? -22.24200 -7.94400  0.35300   1.000 98.79819  ? 146 LYS A HE2  1 
ATOM   2078 H HE3  . LYS A 1 146 ? -21.77000 -7.41800  1.78000   1.000 98.79819  ? 146 LYS A HE3  1 
ATOM   2079 H HZ1  . LYS A 1 146 ? -20.02300 -7.41700  0.31400   1.000 86.63819  ? 146 LYS A HZ1  1 
ATOM   2080 H HZ2  . LYS A 1 146 ? -19.73200 -8.36100  1.37300   1.000 86.63819  ? 146 LYS A HZ2  1 
ATOM   2081 H HZ3  . LYS A 1 146 ? -20.16100 -8.83900  0.07400   1.000 86.63819  ? 146 LYS A HZ3  1 
ATOM   2082 N N    . ARG A 1 147 ? -26.88900 -8.99400  3.15700   1.000 65.36001  ? 147 ARG A N    1 
ATOM   2083 C CA   . ARG A 1 147 ? -27.60000 -7.79000  3.58700   1.000 67.88512  ? 147 ARG A CA   1 
ATOM   2084 C C    . ARG A 1 147 ? -26.65400 -6.96900  4.45800   1.000 72.48072  ? 147 ARG A C    1 
ATOM   2085 O O    . ARG A 1 147 ? -26.42000 -7.30200  5.62400   1.000 79.37113  ? 147 ARG A O    1 
ATOM   2086 C CB   . ARG A 1 147 ? -28.87600 -8.15500  4.33200   1.000 61.48787  ? 147 ARG A CB   1 
ATOM   2087 C CG   . ARG A 1 147 ? -29.61100 -6.97000  4.90200   1.000 63.89034  ? 147 ARG A CG   1 
ATOM   2088 C CD   . ARG A 1 147 ? -30.95500 -7.39100  5.46000   1.000 54.31590  ? 147 ARG A CD   1 
ATOM   2089 N NE   . ARG A 1 147 ? -30.84500 -8.25100  6.63400   1.000 51.05586  ? 147 ARG A NE   1 
ATOM   2090 C CZ   . ARG A 1 147 ? -31.79100 -9.09400  7.02900   1.000 54.56425  ? 147 ARG A CZ   1 
ATOM   2091 N NH1  . ARG A 1 147 ? -32.91200 -9.24800  6.34100   1.000 53.51234  ? 147 ARG A NH1  1 
ATOM   2092 N NH2  . ARG A 1 147 ? -31.60800 -9.80400  8.14000   1.000 65.64173  ? 147 ARG A NH2  1 
ATOM   2093 H H    . ARG A 1 147 ? -26.63000 -9.48800  3.81100   1.000 77.73819  ? 147 ARG A H    1 
ATOM   2094 H HA   . ARG A 1 147 ? -27.84000 -7.25900  2.81200   1.000 79.31819  ? 147 ARG A HA   1 
ATOM   2095 H HB2  . ARG A 1 147 ? -29.47600 -8.60900  3.72000   1.000 72.65819  ? 147 ARG A HB2  1 
ATOM   2096 H HB3  . ARG A 1 147 ? -28.65000 -8.74500  5.06800   1.000 72.65819  ? 147 ARG A HB3  1 
ATOM   2097 H HG2  . ARG A 1 147 ? -29.09100 -6.58200  5.62200   1.000 73.93819  ? 147 ARG A HG2  1 
ATOM   2098 H HG3  . ARG A 1 147 ? -29.76100 -6.31600  4.20200   1.000 73.93819  ? 147 ARG A HG3  1 
ATOM   2099 H HD2  . ARG A 1 147 ? -31.45300 -6.59800  5.71500   1.000 63.42819  ? 147 ARG A HD2  1 
ATOM   2100 H HD3  . ARG A 1 147 ? -31.43600 -7.87700  4.77200   1.000 63.42819  ? 147 ARG A HD3  1 
ATOM   2101 H HE   . ARG A 1 147 ? -30.12300 -8.20900  7.09900   1.000 60.26819  ? 147 ARG A HE   1 
ATOM   2102 H HH11 . ARG A 1 147 ? -33.04700 -8.79600  5.62300   1.000 65.30819  ? 147 ARG A HH11 1 
ATOM   2103 H HH12 . ARG A 1 147 ? -33.51000 -9.80100  6.61600   1.000 65.30819  ? 147 ARG A HH12 1 
ATOM   2104 H HH21 . ARG A 1 147 ? -30.88300 -9.71300  8.59300   1.000 79.39819  ? 147 ARG A HH21 1 
ATOM   2105 H HH22 . ARG A 1 147 ? -32.21300 -10.35500 8.40400   1.000 79.39819  ? 147 ARG A HH22 1 
ATOM   2106 N N    . GLY A 1 148 ? -26.12000 -5.89000  3.89600   1.000 68.08659  ? 148 GLY A N    1 
ATOM   2107 C CA   . GLY A 1 148 ? -25.08900 -5.14500  4.58100   1.000 66.60829  ? 148 GLY A CA   1 
ATOM   2108 C C    . GLY A 1 148 ? -23.82600 -5.97300  4.68500   1.000 79.43516  ? 148 GLY A C    1 
ATOM   2109 O O    . GLY A 1 148 ? -23.17900 -6.24800  3.67100   1.000 74.70011  ? 148 GLY A O    1 
ATOM   2110 H H    . GLY A 1 148 ? -26.33900 -5.57600  3.12600   1.000 82.61819  ? 148 GLY A H    1 
ATOM   2111 H HA2  . GLY A 1 148 ? -24.89100 -4.33000  4.09400   1.000 78.74819  ? 148 GLY A HA2  1 
ATOM   2112 H HA3  . GLY A 1 148 ? -25.38700 -4.91300  5.47400   1.000 78.74819  ? 148 GLY A HA3  1 
ATOM   2113 N N    . ASN A 1 149 ? -23.46500 -6.39100  5.89700   1.000 73.26589  ? 149 ASN A N    1 
ATOM   2114 C CA   . ASN A 1 149 ? -22.27300 -7.19900  6.09900   1.000 73.51184  ? 149 ASN A CA   1 
ATOM   2115 C C    . ASN A 1 149 ? -22.58300 -8.63400  6.49900   1.000 72.28878  ? 149 ASN A C    1 
ATOM   2116 O O    . ASN A 1 149 ? -21.65000 -9.43300  6.64700   1.000 72.11322  ? 149 ASN A O    1 
ATOM   2117 C CB   . ASN A 1 149 ? -21.37300 -6.55900  7.16900   1.000 80.17606  ? 149 ASN A CB   1 
ATOM   2118 C CG   . ASN A 1 149 ? -20.98300 -5.12700  6.83000   1.000 89.59684  ? 149 ASN A CG   1 
ATOM   2119 O OD1  . ASN A 1 149 ? -19.91500 -4.87600  6.26900   1.000 92.41056  ? 149 ASN A OD1  1 
ATOM   2120 N ND2  . ASN A 1 149 ? -21.85100 -4.18100  7.17000   1.000 88.13723  ? 149 ASN A ND2  1 
ATOM   2121 H H    . ASN A 1 149 ? -23.89800 -6.21700  6.62000   1.000 84.62819  ? 149 ASN A H    1 
ATOM   2122 H HA   . ASN A 1 149 ? -21.76700 -7.22900  5.27200   1.000 85.24819  ? 149 ASN A HA   1 
ATOM   2123 H HB2  . ASN A 1 149 ? -21.84700 -6.54900  8.01500   1.000 90.93819  ? 149 ASN A HB2  1 
ATOM   2124 H HB3  . ASN A 1 149 ? -20.55900 -7.08000  7.25000   1.000 90.93819  ? 149 ASN A HB3  1 
ATOM   2125 H HD21 . ASN A 1 149 ? -22.58700 -4.39300  7.56100   1.000 96.67819  ? 149 ASN A HD21 1 
ATOM   2126 H HD22 . ASN A 1 149 ? -21.67700 -3.35600  7.00000   1.000 96.67819  ? 149 ASN A HD22 1 
ATOM   2127 N N    . ASP A 1 150 ? -23.85300 -8.99000  6.66600   1.000 78.00857  ? 150 ASP A N    1 
ATOM   2128 C CA   . ASP A 1 150 ? -24.22700 -10.31000 7.14700   1.000 65.36527  ? 150 ASP A CA   1 
ATOM   2129 C C    . ASP A 1 150 ? -24.86200 -11.09800 6.01900   1.000 63.43877  ? 150 ASP A C    1 
ATOM   2130 O O    . ASP A 1 150 ? -25.68000 -10.56500 5.26300   1.000 61.06138  ? 150 ASP A O    1 
ATOM   2131 C CB   . ASP A 1 150 ? -25.21500 -10.24800 8.31200   1.000 67.18840  ? 150 ASP A CB   1 
ATOM   2132 C CG   . ASP A 1 150 ? -24.84100 -9.22400  9.35000   1.000 72.96226  ? 150 ASP A CG   1 
ATOM   2133 O OD1  . ASP A 1 150 ? -23.68900 -8.74600  9.35400   1.000 81.10634  ? 150 ASP A OD1  1 
ATOM   2134 O OD2  . ASP A 1 150 ? -25.72000 -8.88000  10.16300  1.000 87.07488  ? 150 ASP A OD2  1 
ATOM   2135 H H    . ASP A 1 150 ? -24.52400 -8.47700  6.50500   1.000 91.84819  ? 150 ASP A H    1 
ATOM   2136 H HA   . ASP A 1 150 ? -23.43600 -10.78600 7.44500   1.000 78.61819  ? 150 ASP A HA   1 
ATOM   2137 H HB2  . ASP A 1 150 ? -26.09300 -10.01900 7.96900   1.000 80.72819  ? 150 ASP A HB2  1 
ATOM   2138 H HB3  . ASP A 1 150 ? -25.24600 -11.11500 8.74500   1.000 80.72819  ? 150 ASP A HB3  1 
ATOM   2139 N N    . TYR A 1 151 ? -24.50500 -12.36700 5.92500   1.000 71.88073  ? 151 TYR A N    1 
ATOM   2140 C CA   . TYR A 1 151 ? -25.21800 -13.25100 5.02600   1.000 61.26019  ? 151 TYR A CA   1 
ATOM   2141 C C    . TYR A 1 151 ? -26.51800 -13.70300 5.67100   1.000 54.64964  ? 151 TYR A C    1 
ATOM   2142 O O    . TYR A 1 151 ? -26.60400 -13.88000 6.89000   1.000 56.50283  ? 151 TYR A O    1 
ATOM   2143 C CB   . TYR A 1 151 ? -24.35200 -14.44600 4.67100   1.000 67.17380  ? 151 TYR A CB   1 
ATOM   2144 C CG   . TYR A 1 151 ? -23.25900 -14.10400 3.69500   1.000 73.92140  ? 151 TYR A CG   1 
ATOM   2145 C CD1  . TYR A 1 151 ? -23.55900 -13.79200 2.37900   1.000 76.11654  ? 151 TYR A CD1  1 
ATOM   2146 C CD2  . TYR A 1 151 ? -21.93000 -14.10000 4.08200   1.000 86.42970  ? 151 TYR A CD2  1 
ATOM   2147 C CE1  . TYR A 1 151 ? -22.57000 -13.48800 1.47500   1.000 78.04607  ? 151 TYR A CE1  1 
ATOM   2148 C CE2  . TYR A 1 151 ? -20.93300 -13.79800 3.18400   1.000 101.73763 ? 151 TYR A CE2  1 
ATOM   2149 C CZ   . TYR A 1 151 ? -21.26000 -13.49300 1.88200   1.000 90.46791  ? 151 TYR A CZ   1 
ATOM   2150 O OH   . TYR A 1 151 ? -20.27700 -13.18900 0.97400   1.000 93.75166  ? 151 TYR A OH   1 
ATOM   2151 H H    . TYR A 1 151 ? -23.86400 -12.73600 6.36400   1.000 83.06819  ? 151 TYR A H    1 
ATOM   2152 H HA   . TYR A 1 151 ? -25.43300 -12.77500 4.20900   1.000 72.07819  ? 151 TYR A HA   1 
ATOM   2153 H HB2  . TYR A 1 151 ? -23.93700 -14.78600 5.47900   1.000 80.09819  ? 151 TYR A HB2  1 
ATOM   2154 H HB3  . TYR A 1 151 ? -24.90900 -15.13100 4.27000   1.000 80.09819  ? 151 TYR A HB3  1 
ATOM   2155 H HD1  . TYR A 1 151 ? -24.44700 -13.79200 2.10100   1.000 89.85819  ? 151 TYR A HD1  1 
ATOM   2156 H HD2  . TYR A 1 151 ? -21.70800 -14.31000 4.96000   1.000 101.31819 ? 151 TYR A HD2  1 
ATOM   2157 H HE1  . TYR A 1 151 ? -22.78700 -13.28100 0.59500   1.000 91.12819  ? 151 TYR A HE1  1 
ATOM   2158 H HE2  . TYR A 1 151 ? -20.04300 -13.79900 3.45500   1.000 118.68819 ? 151 TYR A HE2  1 
ATOM   2159 H HH   . TYR A 1 151 ? -19.52300 -13.22600 1.34300   1.000 107.82819 ? 151 TYR A HH   1 
ATOM   2160 N N    . VAL A 1 152 ? -27.53800 -13.86900 4.83600   1.000 60.26674  ? 152 VAL A N    1 
ATOM   2161 C CA   . VAL A 1 152 ? -28.86200 -14.28700 5.26600   1.000 41.44702  ? 152 VAL A CA   1 
ATOM   2162 C C    . VAL A 1 152 ? -29.25300 -15.48200 4.41400   1.000 38.07136  ? 152 VAL A C    1 
ATOM   2163 O O    . VAL A 1 152 ? -29.23800 -15.39800 3.18100   1.000 36.34501  ? 152 VAL A O    1 
ATOM   2164 C CB   . VAL A 1 152 ? -29.89400 -13.15700 5.12900   1.000 39.35817  ? 152 VAL A CB   1 
ATOM   2165 C CG1  . VAL A 1 152 ? -31.24100 -13.62300 5.63900   1.000 43.54275  ? 152 VAL A CG1  1 
ATOM   2166 C CG2  . VAL A 1 152 ? -29.41800 -11.92600 5.88300   1.000 43.76525  ? 152 VAL A CG2  1 
ATOM   2167 H H    . VAL A 1 152 ? -27.48200 -13.74000 3.98700   1.000 77.38819  ? 152 VAL A H    1 
ATOM   2168 H HA   . VAL A 1 152 ? -28.83200 -14.56700 6.19400   1.000 55.67819  ? 152 VAL A HA   1 
ATOM   2169 H HB   . VAL A 1 152 ? -29.98800 -12.92200 4.19300   1.000 52.34819  ? 152 VAL A HB   1 
ATOM   2170 H HG11 . VAL A 1 152 ? -31.83400 -12.85800 5.70400   1.000 58.11819  ? 152 VAL A HG11 1 
ATOM   2171 H HG12 . VAL A 1 152 ? -31.60800 -14.27300 5.02000   1.000 58.11819  ? 152 VAL A HG12 1 
ATOM   2172 H HG13 . VAL A 1 152 ? -31.12500 -14.02600 6.51400   1.000 58.11819  ? 152 VAL A HG13 1 
ATOM   2173 H HG21 . VAL A 1 152 ? -30.11500 -11.25200 5.85800   1.000 55.82819  ? 152 VAL A HG21 1 
ATOM   2174 H HG22 . VAL A 1 152 ? -29.22900 -12.17300 6.80200   1.000 55.82819  ? 152 VAL A HG22 1 
ATOM   2175 H HG23 . VAL A 1 152 ? -28.61400 -11.58600 5.45900   1.000 55.82819  ? 152 VAL A HG23 1 
ATOM   2176 N N    . VAL A 1 153 ? -29.56400 -16.59300 5.05700   1.000 42.44352  ? 153 VAL A N    1 
ATOM   2177 C CA   . VAL A 1 153 ? -30.09000 -17.76100 4.36600   1.000 41.83833  ? 153 VAL A CA   1 
ATOM   2178 C C    . VAL A 1 153 ? -31.60700 -17.71600 4.47200   1.000 43.29847  ? 153 VAL A C    1 
ATOM   2179 O O    . VAL A 1 153 ? -32.16100 -17.54200 5.56500   1.000 44.12429  ? 153 VAL A O    1 
ATOM   2180 C CB   . VAL A 1 153 ? -29.52000 -19.07000 4.94700   1.000 46.77539  ? 153 VAL A CB   1 
ATOM   2181 C CG1  . VAL A 1 153 ? -29.72200 -19.12900 6.45000   1.000 50.84295  ? 153 VAL A CG1  1 
ATOM   2182 C CG2  . VAL A 1 153 ? -30.16300 -20.27400 4.26200   1.000 41.41234  ? 153 VAL A CG2  1 
ATOM   2183 H H    . VAL A 1 153 ? -29.48100 -16.69500 5.90600   1.000 49.51819  ? 153 VAL A H    1 
ATOM   2184 H HA   . VAL A 1 153 ? -29.84900 -17.71700 3.42800   1.000 50.01819  ? 153 VAL A HA   1 
ATOM   2185 H HB   . VAL A 1 153 ? -28.56600 -19.10200 4.77300   1.000 56.64819  ? 153 VAL A HB   1 
ATOM   2186 H HG11 . VAL A 1 153 ? -29.49900 -20.02100 6.75800   1.000 61.22819  ? 153 VAL A HG11 1 
ATOM   2187 H HG12 . VAL A 1 153 ? -29.13700 -18.48200 6.87300   1.000 61.22819  ? 153 VAL A HG12 1 
ATOM   2188 H HG13 . VAL A 1 153 ? -30.64600 -18.93200 6.66300   1.000 61.22819  ? 153 VAL A HG13 1 
ATOM   2189 H HG21 . VAL A 1 153 ? -29.65400 -21.07000 4.48400   1.000 51.25819  ? 153 VAL A HG21 1 
ATOM   2190 H HG22 . VAL A 1 153 ? -31.07600 -20.36900 4.57500   1.000 51.25819  ? 153 VAL A HG22 1 
ATOM   2191 H HG23 . VAL A 1 153 ? -30.15300 -20.13300 3.30200   1.000 51.25819  ? 153 VAL A HG23 1 
ATOM   2192 N N    . ILE A 1 154 ? -32.28400 -17.89500 3.33900   1.000 50.52631  ? 154 ILE A N    1 
ATOM   2193 C CA   . ILE A 1 154 ? -33.72500 -17.69900 3.25800   1.000 46.36777  ? 154 ILE A CA   1 
ATOM   2194 C C    . ILE A 1 154 ? -34.50900 -18.98500 3.00800   1.000 41.53233  ? 154 ILE A C    1 
ATOM   2195 O O    . ILE A 1 154 ? -35.73600 -18.99500 3.19800   1.000 40.95757  ? 154 ILE A O    1 
ATOM   2196 C CB   . ILE A 1 154 ? -34.05500 -16.65900 2.16700   1.000 47.30030  ? 154 ILE A CB   1 
ATOM   2197 C CG1  . ILE A 1 154 ? -33.64100 -17.18800 0.79100   1.000 36.52048  ? 154 ILE A CG1  1 
ATOM   2198 C CG2  . ILE A 1 154 ? -33.35400 -15.34900 2.49500   1.000 44.95266  ? 154 ILE A CG2  1 
ATOM   2199 C CD1  . ILE A 1 154 ? -33.99600 -16.25100 -0.34900  1.000 43.64876  ? 154 ILE A CD1  1 
ATOM   2200 H H    . ILE A 1 154 ? -31.92400 -18.13400 2.59600   1.000 59.71819  ? 154 ILE A H    1 
ATOM   2201 H HA   . ILE A 1 154 ? -34.03300 -17.33500 4.10200   1.000 54.71819  ? 154 ILE A HA   1 
ATOM   2202 H HB   . ILE A 1 154 ? -35.00800 -16.50700 2.16800   1.000 55.09819  ? 154 ILE A HB   1 
ATOM   2203 H HG12 . ILE A 1 154 ? -32.68000 -17.31700 0.78000   1.000 42.38819  ? 154 ILE A HG12 1 
ATOM   2204 H HG13 . ILE A 1 154 ? -34.08800 -18.03100 0.62200   1.000 42.38819  ? 154 ILE A HG13 1 
ATOM   2205 H HG21 . ILE A 1 154 ? -32.40200 -15.45200 2.34000   1.000 51.15819  ? 154 ILE A HG21 1 
ATOM   2206 H HG22 . ILE A 1 154 ? -33.70900 -14.65100 1.92500   1.000 51.15819  ? 154 ILE A HG22 1 
ATOM   2207 H HG23 . ILE A 1 154 ? -33.51700 -15.12900 3.42600   1.000 51.15819  ? 154 ILE A HG23 1 
ATOM   2208 H HD11 . ILE A 1 154 ? -33.79100 -16.68700 -1.19100  1.000 50.00819  ? 154 ILE A HD11 1 
ATOM   2209 H HD12 . ILE A 1 154 ? -34.94300 -16.04600 -0.30500  1.000 50.00819  ? 154 ILE A HD12 1 
ATOM   2210 H HD13 . ILE A 1 154 ? -33.47600 -15.43600 -0.26300  1.000 50.00819  ? 154 ILE A HD13 1 
ATOM   2211 N N    . GLY A 1 155 ? -33.87000 -20.07400 2.59400   1.000 39.82537  ? 155 GLY A N    1 
ATOM   2212 C CA   . GLY A 1 155 ? -34.61000 -21.28400 2.29200   1.000 30.84812  ? 155 GLY A CA   1 
ATOM   2213 C C    . GLY A 1 155 ? -33.69000 -22.30000 1.65100   1.000 35.25383  ? 155 GLY A C    1 
ATOM   2214 O O    . GLY A 1 155 ? -32.47100 -22.12100 1.63800   1.000 34.37110  ? 155 GLY A O    1 
ATOM   2215 H H    . GLY A 1 155 ? -33.02000 -20.13500 2.48200   1.000 51.16819  ? 155 GLY A H    1 
ATOM   2216 H HA2  . GLY A 1 155 ? -34.96400 -21.66200 3.11200   1.000 40.96819  ? 155 GLY A HA2  1 
ATOM   2217 H HA3  . GLY A 1 155 ? -35.34800 -21.09100 1.69700   1.000 40.96819  ? 155 GLY A HA3  1 
ATOM   2218 N N    . VAL A 1 156 ? -34.28800 -23.35800 1.10900   1.000 43.36739  ? 156 VAL A N    1 
ATOM   2219 C CA   . VAL A 1 156 ? -33.53300 -24.42700 0.46500   1.000 38.36151  ? 156 VAL A CA   1 
ATOM   2220 C C    . VAL A 1 156 ? -34.25200 -24.82300 -0.81500  1.000 33.63046  ? 156 VAL A C    1 
ATOM   2221 O O    . VAL A 1 156 ? -35.48500 -24.85100 -0.86000  1.000 39.82953  ? 156 VAL A O    1 
ATOM   2222 C CB   . VAL A 1 156 ? -33.36700 -25.64400 1.39400   1.000 36.16084  ? 156 VAL A CB   1 
ATOM   2223 C CG1  . VAL A 1 156 ? -32.44500 -25.31500 2.57600   1.000 35.93131  ? 156 VAL A CG1  1 
ATOM   2224 C CG2  . VAL A 1 156 ? -34.73600 -26.09600 1.87800   1.000 34.99273  ? 156 VAL A CG2  1 
ATOM   2225 H H    . VAL A 1 156 ? -35.13900 -23.48000 1.10200   1.000 53.02819  ? 156 VAL A H    1 
ATOM   2226 H HA   . VAL A 1 156 ? -32.65000 -24.10200 0.22900   1.000 47.19819  ? 156 VAL A HA   1 
ATOM   2227 H HB   . VAL A 1 156 ? -32.96800 -26.37300 0.89400   1.000 44.99819  ? 156 VAL A HB   1 
ATOM   2228 H HG11 . VAL A 1 156 ? -32.09000 -24.42000 2.46100   1.000 44.82819  ? 156 VAL A HG11 1 
ATOM   2229 H HG12 . VAL A 1 156 ? -32.95700 -25.36600 3.39900   1.000 44.82819  ? 156 VAL A HG12 1 
ATOM   2230 H HG13 . VAL A 1 156 ? -31.71900 -25.95800 2.59700   1.000 44.82819  ? 156 VAL A HG13 1 
ATOM   2231 H HG21 . VAL A 1 156 ? -34.62200 -26.85500 2.47200   1.000 43.62819  ? 156 VAL A HG21 1 
ATOM   2232 H HG22 . VAL A 1 156 ? -35.16300 -25.36800 2.35500   1.000 43.62819  ? 156 VAL A HG22 1 
ATOM   2233 H HG23 . VAL A 1 156 ? -35.27600 -26.35500 1.11600   1.000 43.62819  ? 156 VAL A HG23 1 
ATOM   2234 N N    . HIS A 1 157 ? -33.48400 -25.14900 -1.84700  1.000 34.60907  ? 157 HIS A N    1 
ATOM   2235 C CA   . HIS A 1 157 ? -34.06500 -25.43200 -3.15000  1.000 37.22348  ? 157 HIS A CA   1 
ATOM   2236 C C    . HIS A 1 157 ? -34.99000 -26.63600 -3.06200  1.000 37.35956  ? 157 HIS A C    1 
ATOM   2237 O O    . HIS A 1 157 ? -34.65100 -27.65400 -2.45400  1.000 35.64219  ? 157 HIS A O    1 
ATOM   2238 C CB   . HIS A 1 157 ? -32.95400 -25.68700 -4.16900  1.000 35.10269  ? 157 HIS A CB   1 
ATOM   2239 C CG   . HIS A 1 157 ? -33.45100 -25.84400 -5.57000  1.000 32.52882  ? 157 HIS A CG   1 
ATOM   2240 N ND1  . HIS A 1 157 ? -34.11200 -24.83800 -6.23900  1.000 38.57657  ? 157 HIS A ND1  1 
ATOM   2241 C CD2  . HIS A 1 157 ? -33.38800 -26.88800 -6.42800  1.000 37.57934  ? 157 HIS A CD2  1 
ATOM   2242 C CE1  . HIS A 1 157 ? -34.43400 -25.25500 -7.45000  1.000 52.68096  ? 157 HIS A CE1  1 
ATOM   2243 N NE2  . HIS A 1 157 ? -34.00700 -26.49700 -7.59000  1.000 47.12859  ? 157 HIS A NE2  1 
ATOM   2244 H H    . HIS A 1 157 ? -32.62700 -25.21300 -1.81900  1.000 44.60819  ? 157 HIS A H    1 
ATOM   2245 H HA   . HIS A 1 157 ? -34.58800 -24.67100 -3.44600  1.000 47.04819  ? 157 HIS A HA   1 
ATOM   2246 H HB2  . HIS A 1 157 ? -32.33700 -24.94700 -4.14700  1.000 43.91819  ? 157 HIS A HB2  1 
ATOM   2247 H HB3  . HIS A 1 157 ? -32.49200 -26.50500 -3.92700  1.000 43.91819  ? 157 HIS A HB3  1 
ATOM   2248 H HD2  . HIS A 1 157 ? -32.99900 -27.71600 -6.26200  1.000 45.09819  ? 157 HIS A HD2  1 
ATOM   2249 H HE1  . HIS A 1 157 ? -34.88500 -24.75900 -8.09400  1.000 62.09819  ? 157 HIS A HE1  1 
ATOM   2250 H HE2  . HIS A 1 157 ? -34.09900 -26.98100 -8.29500  1.000 55.38819  ? 157 HIS A HE2  1 
ATOM   2251 N N    . THR A 1 158 ? -36.16600 -26.51900 -3.67000  1.000 39.38834  ? 158 THR A N    1 
ATOM   2252 C CA   . THR A 1 158 ? -37.09600 -27.63200 -3.60200  1.000 38.78325  ? 158 THR A CA   1 
ATOM   2253 C C    . THR A 1 158 ? -37.64100 -28.01300 -4.96900  1.000 38.82632  ? 158 THR A C    1 
ATOM   2254 O O    . THR A 1 158 ? -37.96200 -29.18300 -5.19300  1.000 40.53857  ? 158 THR A O    1 
ATOM   2255 C CB   . THR A 1 158 ? -38.24800 -27.30400 -2.65400  1.000 41.88155  ? 158 THR A CB   1 
ATOM   2256 O OG1  . THR A 1 158 ? -39.04200 -28.47800 -2.44800  1.000 55.49368  ? 158 THR A OG1  1 
ATOM   2257 C CG2  . THR A 1 158 ? -39.12900 -26.23200 -3.23500  1.000 51.51231  ? 158 THR A CG2  1 
ATOM   2258 H H    . THR A 1 158 ? -36.43900 -25.83300 -4.11100  1.000 48.97819  ? 158 THR A H    1 
ATOM   2259 H HA   . THR A 1 158 ? -36.64100 -28.41100 -3.24800  1.000 48.04819  ? 158 THR A HA   1 
ATOM   2260 H HB   . THR A 1 158 ? -37.89600 -26.99300 -1.80500  1.000 52.03819  ? 158 THR A HB   1 
ATOM   2261 H HG1  . THR A 1 158 ? -39.38500 -28.72500 -3.17400  1.000 68.08819  ? 158 THR A HG1  1 
ATOM   2262 H HG21 . THR A 1 158 ? -38.58500 -25.52200 -3.61100  1.000 62.98819  ? 158 THR A HG21 1 
ATOM   2263 H HG22 . THR A 1 158 ? -39.69600 -25.86000 -2.54200  1.000 62.98819  ? 158 THR A HG22 1 
ATOM   2264 H HG23 . THR A 1 158 ? -39.68900 -26.60200 -3.93500  1.000 62.98819  ? 158 THR A HG23 1 
ATOM   2265 N N    . ALA A 1 159 ? -37.74500 -27.06300 -5.89200  1.000 37.12707  ? 159 ALA A N    1 
ATOM   2266 C CA   . ALA A 1 159 ? -38.35000 -27.36900 -7.18200  1.000 39.04930  ? 159 ALA A CA   1 
ATOM   2267 C C    . ALA A 1 159 ? -37.96600 -26.30600 -8.20100  1.000 45.07381  ? 159 ALA A C    1 
ATOM   2268 O O    . ALA A 1 159 ? -37.36900 -25.27800 -7.87100  1.000 48.58930  ? 159 ALA A O    1 
ATOM   2269 C CB   . ALA A 1 159 ? -39.87600 -27.48600 -7.06300  1.000 47.95980  ? 159 ALA A CB   1 
ATOM   2270 H H    . ALA A 1 159 ? -37.47900 -26.25000 -5.80000  1.000 48.23819  ? 159 ALA A H    1 
ATOM   2271 H HA   . ALA A 1 159 ? -38.00900 -28.22100 -7.49600  1.000 49.11819  ? 159 ALA A HA   1 
ATOM   2272 H HB1  . ALA A 1 159 ? -40.23300 -26.64300 -6.74200  1.000 59.34819  ? 159 ALA A HB1  1 
ATOM   2273 H HB2  . ALA A 1 159 ? -40.24600 -27.69100 -7.93600  1.000 59.34819  ? 159 ALA A HB2  1 
ATOM   2274 H HB3  . ALA A 1 159 ? -40.09000 -28.19600 -6.43800  1.000 59.34819  ? 159 ALA A HB3  1 
ATOM   2275 N N    . ALA A 1 160 ? -38.33300 -26.58000 -9.45800  1.000 39.04490  ? 160 ALA A N    1 
ATOM   2276 C CA   . ALA A 1 160 ? -38.04400 -25.72600 -10.60300 1.000 42.81770  ? 160 ALA A CA   1 
ATOM   2277 C C    . ALA A 1 160 ? -38.97600 -26.12000 -11.74500 1.000 53.51331  ? 160 ALA A C    1 
ATOM   2278 O O    . ALA A 1 160 ? -39.29700 -27.29800 -11.92500 1.000 52.66676  ? 160 ALA A O    1 
ATOM   2279 C CB   . ALA A 1 160 ? -36.57900 -25.83500 -11.04800 1.000 48.52377  ? 160 ALA A CB   1 
ATOM   2280 H H    . ALA A 1 160 ? -38.77000 -27.28900 -9.67400  1.000 57.75819  ? 160 ALA A H    1 
ATOM   2281 H HA   . ALA A 1 160 ? -38.22400 -24.80300 -10.36800 1.000 60.98819  ? 160 ALA A HA   1 
ATOM   2282 H HB1  . ALA A 1 160 ? -36.39400 -26.75300 -11.30100 1.000 67.61819  ? 160 ALA A HB1  1 
ATOM   2283 H HB2  . ALA A 1 160 ? -36.43500 -25.24700 -11.80600 1.000 67.61819  ? 160 ALA A HB2  1 
ATOM   2284 H HB3  . ALA A 1 160 ? -36.00500 -25.57200 -10.31100 1.000 67.61819  ? 160 ALA A HB3  1 
ATOM   2285 N N    . ALA A 1 161 ? -39.39000 -25.11800 -12.51900 1.000 63.98253  ? 161 ALA A N    1 
ATOM   2286 C CA   . ALA A 1 161 ? -40.33700 -25.31900 -13.60800 1.000 62.34409  ? 161 ALA A CA   1 
ATOM   2287 C C    . ALA A 1 161 ? -39.70300 -26.07600 -14.76500 1.000 78.40696  ? 161 ALA A C    1 
ATOM   2288 O O    . ALA A 1 161 ? -38.63000 -25.70500 -15.25200 1.000 71.26984  ? 161 ALA A O    1 
ATOM   2289 C CB   . ALA A 1 161 ? -40.85100 -23.97300 -14.12000 1.000 70.24277  ? 161 ALA A CB   1 
ATOM   2290 H H    . ALA A 1 161 ? -39.13200 -24.30200 -12.43000 1.000 84.40819  ? 161 ALA A H    1 
ATOM   2291 H HA   . ALA A 1 161 ? -41.09400 -25.83300 -13.28500 1.000 80.43819  ? 161 ALA A HA   1 
ATOM   2292 H HB1  . ALA A 1 161 ? -41.44200 -24.12800 -14.87300 1.000 88.90819  ? 161 ALA A HB1  1 
ATOM   2293 H HB2  . ALA A 1 161 ? -41.33500 -23.52900 -13.40700 1.000 88.90819  ? 161 ALA A HB2  1 
ATOM   2294 H HB3  . ALA A 1 161 ? -40.09600 -23.43200 -14.39800 1.000 88.90819  ? 161 ALA A HB3  1 
ATOM   2295 N N    . ARG A 1 162 ? -40.39700 -27.12400 -15.22800 1.000 93.91006  ? 162 ARG A N    1 
ATOM   2296 C CA   . ARG A 1 162 ? -39.94300 -27.85600 -16.40900 1.000 97.09886  ? 162 ARG A CA   1 
ATOM   2297 C C    . ARG A 1 162 ? -39.69400 -26.91000 -17.57600 1.000 109.37246 ? 162 ARG A C    1 
ATOM   2298 O O    . ARG A 1 162 ? -38.68500 -27.03400 -18.28000 1.000 109.63809 ? 162 ARG A O    1 
ATOM   2299 C CB   . ARG A 1 162 ? -40.97000 -28.91600 -16.80800 1.000 101.00804 ? 162 ARG A CB   1 
ATOM   2300 C CG   . ARG A 1 162 ? -40.39400 -30.09400 -17.57000 1.000 107.24944 ? 162 ARG A CG   1 
ATOM   2301 C CD   . ARG A 1 162 ? -40.59700 -31.35400 -16.76300 1.000 129.01653 ? 162 ARG A CD   1 
ATOM   2302 N NE   . ARG A 1 162 ? -39.69700 -32.41300 -17.19000 1.000 135.41298 ? 162 ARG A NE   1 
ATOM   2303 C CZ   . ARG A 1 162 ? -39.52300 -33.55400 -16.53900 1.000 141.24551 ? 162 ARG A CZ   1 
ATOM   2304 N NH1  . ARG A 1 162 ? -40.18900 -33.82300 -15.42700 1.000 127.34050 ? 162 ARG A NH1  1 
ATOM   2305 N NH2  . ARG A 1 162 ? -38.65700 -34.44400 -17.01200 1.000 135.32940 ? 162 ARG A NH2  1 
ATOM   2306 H H    . ARG A 1 162 ? -41.12300 -27.42400 -14.87900 1.000 107.27819 ? 162 ARG A H    1 
ATOM   2307 H HA   . ARG A 1 162 ? -39.10900 -28.30500 -16.20100 1.000 109.01819 ? 162 ARG A HA   1 
ATOM   2308 H HB2  . ARG A 1 162 ? -41.39600 -29.25400 -16.00500 1.000 112.17819 ? 162 ARG A HB2  1 
ATOM   2309 H HB3  . ARG A 1 162 ? -41.63600 -28.49900 -17.37700 1.000 112.17819 ? 162 ARG A HB3  1 
ATOM   2310 H HG2  . ARG A 1 162 ? -40.85400 -30.19100 -18.41800 1.000 118.02819 ? 162 ARG A HG2  1 
ATOM   2311 H HG3  . ARG A 1 162 ? -39.44300 -29.96300 -17.70900 1.000 118.02819 ? 162 ARG A HG3  1 
ATOM   2312 H HD2  . ARG A 1 162 ? -40.41500 -31.17300 -15.82900 1.000 145.03819 ? 162 ARG A HD2  1 
ATOM   2313 H HD3  . ARG A 1 162 ? -41.50900 -31.66400 -16.87500 1.000 145.03819 ? 162 ARG A HD3  1 
ATOM   2314 H HE   . ARG A 1 162 ? -39.24800 -32.29100 -17.91300 1.000 151.74819 ? 162 ARG A HE   1 
ATOM   2315 H HH11 . ARG A 1 162 ? -40.75100 -33.25400 -15.11100 1.000 144.28819 ? 162 ARG A HH11 1 
ATOM   2316 H HH12 . ARG A 1 162 ? -40.06000 -34.57000 -15.02000 1.000 144.28819 ? 162 ARG A HH12 1 
ATOM   2317 H HH21 . ARG A 1 162 ? -38.22000 -34.27700 -17.73400 1.000 151.20819 ? 162 ARG A HH21 1 
ATOM   2318 H HH22 . ARG A 1 162 ? -38.53600 -35.18800 -16.59800 1.000 151.20819 ? 162 ARG A HH22 1 
ATOM   2319 N N    . GLY A 1 163 ? -40.60100 -25.96200 -17.80100 1.000 89.88304  ? 163 GLY A N    1 
ATOM   2320 C CA   . GLY A 1 163 ? -40.38400 -24.95500 -18.82100 1.000 101.96609 ? 163 GLY A CA   1 
ATOM   2321 C C    . GLY A 1 163 ? -40.26300 -23.56400 -18.23000 1.000 89.54966  ? 163 GLY A C    1 
ATOM   2322 O O    . GLY A 1 163 ? -41.23600 -23.05500 -17.66800 1.000 90.45375  ? 163 GLY A O    1 
ATOM   2323 H H    . GLY A 1 163 ? -41.34500 -25.88400 -17.37600 1.000 111.84819 ? 163 GLY A H    1 
ATOM   2324 H HA2  . GLY A 1 163 ? -39.57300 -25.15000 -19.31500 1.000 124.48819 ? 163 GLY A HA2  1 
ATOM   2325 H HA3  . GLY A 1 163 ? -41.12900 -24.96000 -19.44200 1.000 124.48819 ? 163 GLY A HA3  1 
ATOM   2326 N N    . GLY A 1 164 ? -39.09300 -22.93800 -18.35000 1.000 85.96679  ? 164 GLY A N    1 
ATOM   2327 C CA   . GLY A 1 164 ? -38.82500 -21.63100 -17.78300 1.000 79.16977  ? 164 GLY A CA   1 
ATOM   2328 C C    . GLY A 1 164 ? -37.68000 -21.66900 -16.79600 1.000 81.46775  ? 164 GLY A C    1 
ATOM   2329 O O    . GLY A 1 164 ? -37.08300 -22.71300 -16.52800 1.000 100.04235 ? 164 GLY A O    1 
ATOM   2330 H H    . GLY A 1 164 ? -38.42000 -23.26800 -18.77200 1.000 102.24819 ? 164 GLY A H    1 
ATOM   2331 H HA2  . GLY A 1 164 ? -38.59900 -21.01000 -18.49300 1.000 95.09819  ? 164 GLY A HA2  1 
ATOM   2332 H HA3  . GLY A 1 164 ? -39.61500 -21.30300 -17.32600 1.000 95.09819  ? 164 GLY A HA3  1 
ATOM   2333 N N    . ASN A 1 165 ? -37.36200 -20.48300 -16.25800 1.000 102.43413 ? 165 ASN A N    1 
ATOM   2334 C CA   . ASN A 1 165 ? -36.28900 -20.30100 -15.28700 1.000 84.74217  ? 165 ASN A CA   1 
ATOM   2335 C C    . ASN A 1 165 ? -36.76700 -20.51800 -13.85900 1.000 78.22947  ? 165 ASN A C    1 
ATOM   2336 O O    . ASN A 1 165 ? -35.93900 -20.73300 -12.96500 1.000 74.42674  ? 165 ASN A O    1 
ATOM   2337 C CB   . ASN A 1 165 ? -35.68500 -18.89100 -15.41200 1.000 88.05070  ? 165 ASN A CB   1 
ATOM   2338 C CG   . ASN A 1 165 ? -35.41900 -18.49100 -16.85400 1.000 106.54847 ? 165 ASN A CG   1 
ATOM   2339 O OD1  . ASN A 1 165 ? -34.45000 -18.93600 -17.47000 1.000 102.05661 ? 165 ASN A OD1  1 
ATOM   2340 N ND2  . ASN A 1 165 ? -36.29500 -17.66100 -17.40500 1.000 109.30144 ? 165 ASN A ND2  1 
ATOM   2341 H H    . ASN A 1 165 ? -37.77100 -19.75100 -16.45100 1.000 107.96819 ? 165 ASN A H    1 
ATOM   2342 H HA   . ASN A 1 165 ? -35.58700 -20.94500 -15.46900 1.000 88.51819  ? 165 ASN A HA   1 
ATOM   2343 H HB2  . ASN A 1 165 ? -36.31100 -18.25600 -15.03700 1.000 91.77819  ? 165 ASN A HB2  1 
ATOM   2344 H HB3  . ASN A 1 165 ? -34.84500 -18.85900 -14.92800 1.000 91.77819  ? 165 ASN A HB3  1 
ATOM   2345 H HD21 . ASN A 1 165 ? -36.96200 -17.37300 -16.94500 1.000 113.12819 ? 165 ASN A HD21 1 
ATOM   2346 H HD22 . ASN A 1 165 ? -36.19100 -17.40500 -18.21900 1.000 113.12819 ? 165 ASN A HD22 1 
ATOM   2347 N N    . THR A 1 166 ? -38.08000 -20.51400 -13.63700 1.000 54.90684  ? 166 THR A N    1 
ATOM   2348 C CA   . THR A 1 166 ? -38.63100 -20.52000 -12.28800 1.000 58.55804  ? 166 THR A CA   1 
ATOM   2349 C C    . THR A 1 166 ? -37.96500 -21.57400 -11.40800 1.000 45.44968  ? 166 THR A C    1 
ATOM   2350 O O    . THR A 1 166 ? -37.83500 -22.73500 -11.79500 1.000 58.71145  ? 166 THR A O    1 
ATOM   2351 C CB   . THR A 1 166 ? -40.14100 -20.77600 -12.33500 1.000 59.54946  ? 166 THR A CB   1 
ATOM   2352 O OG1  . THR A 1 166 ? -40.78600 -19.83600 -13.20500 1.000 70.57798  ? 166 THR A OG1  1 
ATOM   2353 C CG2  . THR A 1 166 ? -40.72000 -20.66300 -10.92700 1.000 45.71770  ? 166 THR A CG2  1 
ATOM   2354 H H    . THR A 1 166 ? -38.67700 -20.50800 -14.25600 1.000 66.26819  ? 166 THR A H    1 
ATOM   2355 H HA   . THR A 1 166 ? -38.48600 -19.65100 -11.88400 1.000 72.51819  ? 166 THR A HA   1 
ATOM   2356 H HB   . THR A 1 166 ? -40.30200 -21.67500 -12.65900 1.000 73.27819  ? 166 THR A HB   1 
ATOM   2357 H HG1  . THR A 1 166 ? -41.61700 -19.95700 -13.19200 1.000 84.74819  ? 166 THR A HG1  1 
ATOM   2358 H HG21 . THR A 1 166 ? -41.68800 -20.61400 -10.97200 1.000 58.34819  ? 166 THR A HG21 1 
ATOM   2359 H HG22 . THR A 1 166 ? -40.47000 -21.43700 -10.39900 1.000 58.34819  ? 166 THR A HG22 1 
ATOM   2360 H HG23 . THR A 1 166 ? -40.38500 -19.86200 -10.49400 1.000 58.34819  ? 166 THR A HG23 1 
ATOM   2361 N N    . VAL A 1 167 ? -37.55200 -21.16000 -10.21100 1.000 42.20185  ? 167 VAL A N    1 
ATOM   2362 C CA   . VAL A 1 167 ? -37.06600 -22.05500 -9.16600  1.000 41.32045  ? 167 VAL A CA   1 
ATOM   2363 C C    . VAL A 1 167 ? -37.88900 -21.78000 -7.91300  1.000 39.56980  ? 167 VAL A C    1 
ATOM   2364 O O    . VAL A 1 167 ? -38.32200 -20.64600 -7.69000  1.000 40.81171  ? 167 VAL A O    1 
ATOM   2365 C CB   . VAL A 1 167 ? -35.55900 -21.85400 -8.89500  1.000 38.41602  ? 167 VAL A CB   1 
ATOM   2366 C CG1  . VAL A 1 167 ? -34.73400 -22.38800 -10.06100 1.000 45.48370  ? 167 VAL A CG1  1 
ATOM   2367 C CG2  . VAL A 1 167 ? -35.25000 -20.39000 -8.66400  1.000 43.69216  ? 167 VAL A CG2  1 
ATOM   2368 H H    . VAL A 1 167 ? -37.54500 -20.33300 -9.97500  1.000 52.76819  ? 167 VAL A H    1 
ATOM   2369 H HA   . VAL A 1 167 ? -37.21000 -22.97600 -9.43300  1.000 53.27819  ? 167 VAL A HA   1 
ATOM   2370 H HB   . VAL A 1 167 ? -35.31000 -22.34600 -8.09700  1.000 50.24819  ? 167 VAL A HB   1 
ATOM   2371 H HG11 . VAL A 1 167 ? -33.79300 -22.25400 -9.86800  1.000 57.59819  ? 167 VAL A HG11 1 
ATOM   2372 H HG12 . VAL A 1 167 ? -34.91900 -23.33400 -10.17100 1.000 57.59819  ? 167 VAL A HG12 1 
ATOM   2373 H HG13 . VAL A 1 167 ? -34.97900 -21.90700 -10.86700 1.000 57.59819  ? 167 VAL A HG13 1 
ATOM   2374 H HG21 . VAL A 1 167 ? -34.31000 -20.30000 -8.44200  1.000 56.33819  ? 167 VAL A HG21 1 
ATOM   2375 H HG22 . VAL A 1 167 ? -35.44600 -19.89200 -9.47300  1.000 56.33819  ? 167 VAL A HG22 1 
ATOM   2376 H HG23 . VAL A 1 167 ? -35.79400 -20.06100 -7.93200  1.000 56.33819  ? 167 VAL A HG23 1 
ATOM   2377 N N    . ILE A 1 168 ? -38.14300 -22.80700 -7.11000  1.000 48.23214  ? 168 ILE A N    1 
ATOM   2378 C CA   . ILE A 1 168 ? -38.88300 -22.64200 -5.86300  1.000 39.39122  ? 168 ILE A CA   1 
ATOM   2379 C C    . ILE A 1 168 ? -37.91800 -22.82100 -4.69800  1.000 41.38997  ? 168 ILE A C    1 
ATOM   2380 O O    . ILE A 1 168 ? -37.09200 -23.74400 -4.69600  1.000 36.26766  ? 168 ILE A O    1 
ATOM   2381 C CB   . ILE A 1 168 ? -40.06600 -23.62500 -5.76500  1.000 42.66746  ? 168 ILE A CB   1 
ATOM   2382 C CG1  . ILE A 1 168 ? -41.03100 -23.43600 -6.94600  1.000 45.12093  ? 168 ILE A CG1  1 
ATOM   2383 C CG2  . ILE A 1 168 ? -40.82000 -23.45500 -4.46600  1.000 41.73186  ? 168 ILE A CG2  1 
ATOM   2384 C CD1  . ILE A 1 168 ? -41.36800 -21.99500 -7.29500  1.000 64.74763  ? 168 ILE A CD1  1 
ATOM   2385 H H    . ILE A 1 168 ? -37.89600 -23.61600 -7.26500  1.000 59.17819  ? 168 ILE A H    1 
ATOM   2386 H HA   . ILE A 1 168 ? -39.23300 -21.74000 -5.81200  1.000 49.43819  ? 168 ILE A HA   1 
ATOM   2387 H HB   . ILE A 1 168 ? -39.71500 -24.52900 -5.79900  1.000 53.24819  ? 168 ILE A HB   1 
ATOM   2388 H HG12 . ILE A 1 168 ? -40.63300 -23.83900 -7.73300  1.000 54.74819  ? 168 ILE A HG12 1 
ATOM   2389 H HG13 . ILE A 1 168 ? -41.86400 -23.88700 -6.73900  1.000 54.74819  ? 168 ILE A HG13 1 
ATOM   2390 H HG21 . ILE A 1 168 ? -41.61700 -24.00700 -4.48900  1.000 52.80819  ? 168 ILE A HG21 1 
ATOM   2391 H HG22 . ILE A 1 168 ? -40.25200 -23.72900 -3.72900  1.000 52.80819  ? 168 ILE A HG22 1 
ATOM   2392 H HG23 . ILE A 1 168 ? -41.06800 -22.52300 -4.36500  1.000 52.80819  ? 168 ILE A HG23 1 
ATOM   2393 H HD11 . ILE A 1 168 ? -42.13700 -21.98600 -7.88600  1.000 77.58819  ? 168 ILE A HD11 1 
ATOM   2394 H HD12 . ILE A 1 168 ? -41.57200 -21.51300 -6.47800  1.000 77.58819  ? 168 ILE A HD12 1 
ATOM   2395 H HD13 . ILE A 1 168 ? -40.60700 -21.58900 -7.73700  1.000 77.58819  ? 168 ILE A HD13 1 
ATOM   2396 N N    . CYS A 1 169 ? -38.03700 -21.94500 -3.69700  1.000 45.08414  ? 169 CYS A N    1 
ATOM   2397 C CA   . CYS A 1 169 ? -37.17600 -21.95200 -2.51200  1.000 36.92787  ? 169 CYS A CA   1 
ATOM   2398 C C    . CYS A 1 169 ? -38.04600 -22.15300 -1.27600  1.000 40.86343  ? 169 CYS A C    1 
ATOM   2399 O O    . CYS A 1 169 ? -38.72300 -21.22000 -0.83100  1.000 47.68112  ? 169 CYS A O    1 
ATOM   2400 C CB   . CYS A 1 169 ? -36.37000 -20.65600 -2.41700  1.000 35.84462  ? 169 CYS A CB   1 
ATOM   2401 S SG   . CYS A 1 169 ? -35.58500 -20.27300 -0.82400  1.000 40.24135  ? 169 CYS A SG   1 
ATOM   2402 H H    . CYS A 1 169 ? -38.62700 -21.31900 -3.68200  1.000 55.02819  ? 169 CYS A H    1 
ATOM   2403 H HA   . CYS A 1 169 ? -36.55300 -22.69300 -2.56900  1.000 46.10819  ? 169 CYS A HA   1 
ATOM   2404 H HB2  . CYS A 1 169 ? -35.66700 -20.68800 -3.08300  1.000 44.48819  ? 169 CYS A HB2  1 
ATOM   2405 H HB3  . CYS A 1 169 ? -36.96600 -19.91900 -2.62200  1.000 44.48819  ? 169 CYS A HB3  1 
ATOM   2406 H HG   . CYS A 1 169 ? -34.81900 -21.15500 -0.55400  1.000 50.33819  ? 169 CYS A HG   1 
ATOM   2407 N N    . ALA A 1 170 ? -37.98400 -23.35700 -0.70200  1.000 37.96804  ? 170 ALA A N    1 
ATOM   2408 C CA   . ALA A 1 170 ? -38.83000 -23.71100 0.43000   1.000 33.85394  ? 170 ALA A CA   1 
ATOM   2409 C C    . ALA A 1 170 ? -38.39900 -22.93100 1.65500   1.000 33.26152  ? 170 ALA A C    1 
ATOM   2410 O O    . ALA A 1 170 ? -37.20400 -22.81800 1.93100   1.000 35.41844  ? 170 ALA A O    1 
ATOM   2411 C CB   . ALA A 1 170 ? -38.73900 -25.20900 0.70900   1.000 39.94412  ? 170 ALA A CB   1 
ATOM   2412 H H    . ALA A 1 170 ? -37.45600 -23.98700 -0.95400  1.000 51.21819  ? 170 ALA A H    1 
ATOM   2413 H HA   . ALA A 1 170 ? -39.75300 -23.48900 0.23000   1.000 46.47819  ? 170 ALA A HA   1 
ATOM   2414 H HB1  . ALA A 1 170 ? -39.03400 -25.69500 -0.07700  1.000 54.11819  ? 170 ALA A HB1  1 
ATOM   2415 H HB2  . ALA A 1 170 ? -37.81800 -25.43600 0.91200   1.000 54.11819  ? 170 ALA A HB2  1 
ATOM   2416 H HB3  . ALA A 1 170 ? -39.30800 -25.42400 1.46400   1.000 54.11819  ? 170 ALA A HB3  1 
ATOM   2417 N N    . THR A 1 171 ? -39.36500 -22.40000 2.39700   1.000 39.14989  ? 171 THR A N    1 
ATOM   2418 C CA   . THR A 1 171 ? -39.05400 -21.49800 3.49200   1.000 43.76658  ? 171 THR A CA   1 
ATOM   2419 C C    . THR A 1 171 ? -39.73100 -21.92900 4.78500   1.000 48.58136  ? 171 THR A C    1 
ATOM   2420 O O    . THR A 1 171 ? -40.64000 -22.76900 4.78800   1.000 45.32720  ? 171 THR A O    1 
ATOM   2421 C CB   . THR A 1 171 ? -39.48800 -20.06000 3.18000   1.000 40.85490  ? 171 THR A CB   1 
ATOM   2422 O OG1  . THR A 1 171 ? -40.92000 -19.97900 3.22900   1.000 45.61555  ? 171 THR A OG1  1 
ATOM   2423 C CG2  . THR A 1 171 ? -38.98300 -19.62200 1.80700   1.000 36.63155  ? 171 THR A CG2  1 
ATOM   2424 H H    . THR A 1 171 ? -40.20500 -22.54700 2.28500   1.000 50.77819  ? 171 THR A H    1 
ATOM   2425 H HA   . THR A 1 171 ? -38.09700 -21.49400 3.64500   1.000 56.11819  ? 171 THR A HA   1 
ATOM   2426 H HB   . THR A 1 171 ? -39.11200 -19.46200 3.84500   1.000 51.90819  ? 171 THR A HB   1 
ATOM   2427 H HG1  . THR A 1 171 ? -41.16900 -19.19500 3.05900   1.000 57.12819  ? 171 THR A HG1  1 
ATOM   2428 H HG21 . THR A 1 171 ? -38.01500 -19.56500 1.81500   1.000 46.70819  ? 171 THR A HG21 1 
ATOM   2429 H HG22 . THR A 1 171 ? -39.25300 -20.25800 1.13400   1.000 46.70819  ? 171 THR A HG22 1 
ATOM   2430 H HG23 . THR A 1 171 ? -39.34700 -18.75100 1.58300   1.000 46.70819  ? 171 THR A HG23 1 
ATOM   2431 N N    . GLN A 1 172 ? -39.25000 -21.31200 5.87600   1.000 53.59902  ? 172 GLN A N    1 
ATOM   2432 C CA   . GLN A 1 172 ? -39.84100 -21.30500 7.22300   1.000 53.52425  ? 172 GLN A CA   1 
ATOM   2433 C C    . GLN A 1 172 ? -39.28800 -22.46400 8.03500   1.000 53.83062  ? 172 GLN A C    1 
ATOM   2434 O O    . GLN A 1 172 ? -38.71600 -22.27900 9.11500   1.000 62.03250  ? 172 GLN A O    1 
ATOM   2435 C CB   . GLN A 1 172 ? -41.36900 -21.36400 7.18100   1.000 60.20491  ? 172 GLN A CB   1 
ATOM   2436 C CG   . GLN A 1 172 ? -42.05500 -20.02300 7.49900   1.000 76.99146  ? 172 GLN A CG   1 
ATOM   2437 C CD   . GLN A 1 172 ? -42.36000 -19.81900 8.98900   1.000 94.37247  ? 172 GLN A CD   1 
ATOM   2438 O OE1  . GLN A 1 172 ? -43.14100 -20.56600 9.58800   1.000 88.45105  ? 172 GLN A OE1  1 
ATOM   2439 N NE2  . GLN A 1 172 ? -41.75500 -18.79200 9.58400   1.000 93.30235  ? 172 GLN A NE2  1 
ATOM   2440 H H    . GLN A 1 172 ? -38.52200 -20.85500 5.85200   1.000 63.19819  ? 172 GLN A H    1 
ATOM   2441 H HA   . GLN A 1 172 ? -39.58700 -20.48300 7.67100   1.000 62.48819  ? 172 GLN A HA   1 
ATOM   2442 H HB2  . GLN A 1 172 ? -41.69300 -21.63700 6.31500   1.000 69.99819  ? 172 GLN A HB2  1 
ATOM   2443 H HB3  . GLN A 1 172 ? -41.66400 -22.00100 7.85000   1.000 69.99819  ? 172 GLN A HB3  1 
ATOM   2444 H HG2  . GLN A 1 172 ? -41.47700 -19.29900 7.21200   1.000 89.15819  ? 172 GLN A HG2  1 
ATOM   2445 H HG3  . GLN A 1 172 ? -42.89600 -19.98100 7.01700   1.000 89.15819  ? 172 GLN A HG3  1 
ATOM   2446 H HE21 . GLN A 1 172 ? -41.21900 -18.29000 9.13600   1.000 107.11819 ? 172 GLN A HE21 1 
ATOM   2447 H HE22 . GLN A 1 172 ? -41.89500 -18.63500 10.41800  1.000 107.11819 ? 172 GLN A HE22 1 
HETATM 2448 C C01  . AG7 B 2 .   ? -40.27600 -30.51100 -9.33000  1.000 44.10349  ? 201 AG7 A C01  1 
HETATM 2449 C C02  . AG7 B 2 .   ? -40.59300 -31.51900 -8.24200  1.000 49.88006  ? 201 AG7 A C02  1 
HETATM 2450 O O03  . AG7 B 2 .   ? -39.30800 -29.78500 -9.28400  1.000 42.42321  ? 201 AG7 A O03  1 
HETATM 2451 C C04  . AG7 B 2 .   ? -39.67200 -31.57800 -7.02200  1.000 40.10330  ? 201 AG7 A C04  1 
HETATM 2452 C C05  . AG7 B 2 .   ? -40.26000 -32.55000 -6.00200  1.000 43.29810  ? 201 AG7 A C05  1 
HETATM 2453 C C06  . AG7 B 2 .   ? -41.36200 -31.96500 -5.15600  1.000 46.84302  ? 201 AG7 A C06  1 
HETATM 2454 C C07  . AG7 B 2 .   ? -41.16100 -30.93600 -4.24900  1.000 41.61182  ? 201 AG7 A C07  1 
HETATM 2455 C C08  . AG7 B 2 .   ? -42.20900 -30.43200 -3.48100  1.000 50.30977  ? 201 AG7 A C08  1 
HETATM 2456 C C09  . AG7 B 2 .   ? -43.47300 -30.97000 -3.62500  1.000 49.08216  ? 201 AG7 A C09  1 
HETATM 2457 C C10  . AG7 B 2 .   ? -43.71300 -31.98400 -4.50500  1.000 53.80441  ? 201 AG7 A C10  1 
HETATM 2458 C C11  . AG7 B 2 .   ? -42.65500 -32.46500 -5.25600  1.000 56.24777  ? 201 AG7 A C11  1 
HETATM 2459 N N12  . AG7 B 2 .   ? -37.23900 -31.48400 -7.07500  1.000 42.78512  ? 201 AG7 A N12  1 
HETATM 2460 C C13  . AG7 B 2 .   ? -35.88700 -31.81800 -7.46800  1.000 45.83264  ? 201 AG7 A C13  1 
HETATM 2461 C C14  . AG7 B 2 .   ? -35.28800 -30.62200 -8.19900  1.000 39.04377  ? 201 AG7 A C14  1 
HETATM 2462 C C15  . AG7 B 2 .   ? -35.89000 -30.14700 -9.54500  1.000 38.64816  ? 201 AG7 A C15  1 
HETATM 2463 C C16  . AG7 B 2 .   ? -35.05500 -29.02700 -10.17100 1.000 38.10118  ? 201 AG7 A C16  1 
HETATM 2464 N N17  . AG7 B 2 .   ? -34.92200 -29.28400 -11.47700 1.000 45.43347  ? 201 AG7 A N17  1 
HETATM 2465 O O18  . AG7 B 2 .   ? -34.56300 -28.06300 -9.60600  1.000 39.96309  ? 201 AG7 A O18  1 
HETATM 2466 C C19  . AG7 B 2 .   ? -35.08600 -32.16800 -6.21400  1.000 48.10777  ? 201 AG7 A C19  1 
HETATM 2467 C C20  . AG7 B 2 .   ? -35.67000 -33.32900 -5.42800  1.000 45.61509  ? 201 AG7 A C20  1 
HETATM 2468 C C21  . AG7 B 2 .   ? -35.76800 -34.62400 -6.19000  1.000 57.03679  ? 201 AG7 A C21  1 
HETATM 2469 O O22  . AG7 B 2 .   ? -36.70800 -35.36800 -5.64800  1.000 73.42568  ? 201 AG7 A O22  1 
HETATM 2470 O O23  . AG7 B 2 .   ? -35.10700 -34.99600 -7.12700  1.000 51.75219  ? 201 AG7 A O23  1 
HETATM 2471 C C47  . AG7 B 2 .   ? -38.33900 -32.08000 -7.53600  1.000 45.00928  ? 201 AG7 A C47  1 
HETATM 2472 O O48  . AG7 B 2 .   ? -38.29600 -32.97400 -8.36100  1.000 53.25216  ? 201 AG7 A O48  1 
HETATM 2473 C C50  . AG7 B 2 .   ? -37.47800 -36.28500 -6.43100  1.000 97.53908  ? 201 AG7 A C50  1 
HETATM 2474 C C53  . AG7 B 2 .   ? -38.83600 -36.18200 -5.77200  1.000 97.93432  ? 201 AG7 A C53  1 
HETATM 2475 C C57  . AG7 B 2 .   ? -41.20800 -30.41800 -10.55700 1.000 58.63446  ? 201 AG7 A C57  1 
HETATM 2476 N N58  . AG7 B 2 .   ? -41.60100 -29.01300 -10.48800 1.000 53.56320  ? 201 AG7 A N58  1 
HETATM 2477 C C59  . AG7 B 2 .   ? -42.85700 -28.54600 -10.27300 1.000 59.64227  ? 201 AG7 A C59  1 
HETATM 2478 O O60  . AG7 B 2 .   ? -43.85500 -29.23800 -10.11000 1.000 62.77711  ? 201 AG7 A O60  1 
HETATM 2479 C C78  . AG7 B 2 .   ? -40.54600 -30.91600 -11.84000 1.000 57.35639  ? 201 AG7 A C78  1 
HETATM 2480 C C81  . AG7 B 2 .   ? -41.12400 -30.05800 -12.95600 1.000 64.29479  ? 201 AG7 A C81  1 
HETATM 2481 F F1   . AG7 B 2 .   ? -44.51200 -30.51700 -2.91000  1.000 52.13911  ? 201 AG7 A F1   1 
HETATM 2482 C C82  . AG7 B 2 .   ? -39.01900 -30.92600 -11.90200 1.000 64.96952  ? 201 AG7 A C82  1 
HETATM 2483 C C83  . AG7 B 2 .   ? -35.56900 -30.48200 -11.94800 1.000 43.81377  ? 201 AG7 A C83  1 
HETATM 2484 C C84  . AG7 B 2 .   ? -35.92600 -31.21300 -10.64700 1.000 41.92630  ? 201 AG7 A C84  1 
HETATM 2485 C C1   . AG7 B 2 .   ? -42.99400 -27.05300 -10.18100 1.000 65.85013  ? 201 AG7 A C1   1 
HETATM 2486 C C2   . AG7 B 2 .   ? -44.07700 -26.34900 -9.58300  1.000 79.05950  ? 201 AG7 A C2   1 
HETATM 2487 C C3   . AG7 B 2 .   ? -43.75100 -25.03400 -9.70000  1.000 78.52106  ? 201 AG7 A C3   1 
HETATM 2488 O O4   . AG7 B 2 .   ? -42.55500 -24.96400 -10.31100 1.000 73.42470  ? 201 AG7 A O4   1 
HETATM 2489 N N5   . AG7 B 2 .   ? -42.09100 -26.20800 -10.59800 1.000 66.76934  ? 201 AG7 A N5   1 
HETATM 2490 C C4   . AG7 B 2 .   ? -44.43000 -23.77000 -9.30000  1.000 56.74011  ? 201 AG7 A C4   1 
HETATM 2491 H H2   . AG7 B 2 .   ? -40.68100 -32.40200 -8.63400  1.000 63.37819  ? 201 AG7 A H2   1 
HETATM 2492 H H3   . AG7 B 2 .   ? -41.49300 -31.29200 -7.95900  1.000 63.37819  ? 201 AG7 A H3   1 
HETATM 2493 H H27  . AG7 B 2 .   ? -39.58600 -30.69400 -6.63300  1.000 53.38819  ? 201 AG7 A H27  1 
HETATM 2494 H H28  . AG7 B 2 .   ? -40.59300 -33.33000 -6.47300  1.000 57.47819  ? 201 AG7 A H28  1 
HETATM 2495 H H29  . AG7 B 2 .   ? -39.55000 -32.86600 -5.42200  1.000 57.47819  ? 201 AG7 A H29  1 
HETATM 2496 H H30  . AG7 B 2 .   ? -40.31500 -30.56600 -4.14100  1.000 57.16819  ? 201 AG7 A H30  1 
HETATM 2497 H H31  . AG7 B 2 .   ? -42.06300 -29.74000 -2.87800  1.000 67.76819  ? 201 AG7 A H31  1 
HETATM 2498 H H33  . AG7 B 2 .   ? -44.56600 -32.34200 -4.59900  1.000 69.62819  ? 201 AG7 A H33  1 
HETATM 2499 H H34  . AG7 B 2 .   ? -42.82100 -33.15800 -5.85300  1.000 72.38819  ? 201 AG7 A H34  1 
HETATM 2500 H H49  . AG7 B 2 .   ? -37.33300 -30.85000 -6.50100  1.000 57.53819  ? 201 AG7 A H49  1 
HETATM 2501 H H91  . AG7 B 2 .   ? -35.92600 -32.58600 -8.05900  1.000 61.04819  ? 201 AG7 A H91  1 
HETATM 2502 H H35  . AG7 B 2 .   ? -35.26000 -29.87200 -7.58500  1.000 52.65819  ? 201 AG7 A H35  1 
HETATM 2503 H H36  . AG7 B 2 .   ? -34.35800 -30.82300 -8.38500  1.000 52.65819  ? 201 AG7 A H36  1 
HETATM 2504 H H94  . AG7 B 2 .   ? -36.77600 -29.79700 -9.36300  1.000 50.61819  ? 201 AG7 A H94  1 
HETATM 2505 H H39  . AG7 B 2 .   ? -34.47900 -28.76400 -11.99900 1.000 56.61819  ? 201 AG7 A H39  1 
HETATM 2506 H H191 . AG7 B 2 .   ? -34.17900 -32.37900 -6.48200  1.000 65.09819  ? 201 AG7 A H191 1 
HETATM 2507 H H41  . AG7 B 2 .   ? -36.56600 -33.11500 -5.12500  1.000 62.17819  ? 201 AG7 A H41  1 
HETATM 2508 H H42  . AG7 B 2 .   ? -35.16200 -33.48700 -4.61800  1.000 62.17819  ? 201 AG7 A H42  1 
HETATM 2509 H H51  . AG7 B 2 .   ? -37.50100 -36.00900 -7.36000  1.000 121.17819 ? 201 AG7 A H51  1 
HETATM 2510 H H52  . AG7 B 2 .   ? -37.11400 -37.18200 -6.37500  1.000 121.17819 ? 201 AG7 A H52  1 
HETATM 2511 H H53  . AG7 B 2 .   ? -38.85300 -36.65500 -4.92600  1.000 121.76819 ? 201 AG7 A H53  1 
HETATM 2512 H H54  . AG7 B 2 .   ? -39.09400 -35.25900 -5.62500  1.000 121.76819 ? 201 AG7 A H54  1 
HETATM 2513 H H56  . AG7 B 2 .   ? -39.50100 -36.58800 -6.34900  1.000 121.76819 ? 201 AG7 A H56  1 
HETATM 2514 H H77  . AG7 B 2 .   ? -42.00400 -30.94600 -10.38700 1.000 71.18819  ? 201 AG7 A H77  1 
HETATM 2515 H H61  . AG7 B 2 .   ? -40.97100 -28.43200 -10.56000 1.000 65.47819  ? 201 AG7 A H61  1 
HETATM 2516 H H79  . AG7 B 2 .   ? -40.84600 -31.82700 -11.98500 1.000 67.98819  ? 201 AG7 A H79  1 
HETATM 2517 H H82  . AG7 B 2 .   ? -42.09000 -30.00400 -12.88200 1.000 74.70819  ? 201 AG7 A H82  1 
HETATM 2518 H H84  . AG7 B 2 .   ? -40.77200 -29.15500 -12.91200 1.000 74.70819  ? 201 AG7 A H84  1 
HETATM 2519 H H85  . AG7 B 2 .   ? -40.91600 -30.40300 -13.83700 1.000 74.70819  ? 201 AG7 A H85  1 
HETATM 2520 H H86  . AG7 B 2 .   ? -38.68700 -31.01700 -12.80900 1.000 77.72819  ? 201 AG7 A H86  1 
HETATM 2521 H H87  . AG7 B 2 .   ? -38.65100 -30.10700 -11.53600 1.000 77.72819  ? 201 AG7 A H87  1 
HETATM 2522 H H88  . AG7 B 2 .   ? -38.67800 -31.66900 -11.38500 1.000 77.72819  ? 201 AG7 A H88  1 
HETATM 2523 H H89  . AG7 B 2 .   ? -34.97100 -30.99900 -12.50900 1.000 53.53819  ? 201 AG7 A H89  1 
HETATM 2524 H H90  . AG7 B 2 .   ? -36.35700 -30.27400 -12.47400 1.000 53.53819  ? 201 AG7 A H90  1 
HETATM 2525 H H92  . AG7 B 2 .   ? -36.76700 -31.68200 -10.69400 1.000 52.76819  ? 201 AG7 A H92  1 
HETATM 2526 H H93  . AG7 B 2 .   ? -35.24400 -31.87900 -10.46900 1.000 52.76819  ? 201 AG7 A H93  1 
HETATM 2527 H H8   . AG7 B 2 .   ? -44.84400 -26.70600 -9.19700  1.000 96.39819  ? 201 AG7 A H8   1 
HETATM 2528 H H5   . AG7 B 2 .   ? -43.91800 -23.29400 -8.62700  1.000 69.88819  ? 201 AG7 A H5   1 
HETATM 2529 H H6   . AG7 B 2 .   ? -45.31100 -23.94500 -8.93400  1.000 69.88819  ? 201 AG7 A H6   1 
HETATM 2530 H H7   . AG7 B 2 .   ? -44.52700 -23.19300 -10.07300 1.000 69.88819  ? 201 AG7 A H7   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . SER A 4   ? 0.54449 0.63166 0.73022 -0.04182 0.00970  -0.01422 4   SER A N   
2    C CA  . SER A 4   ? 0.63746 0.72977 0.81355 -0.04188 -0.00429 -0.02852 4   SER A CA  
3    C C   . SER A 4   ? 0.58585 0.66623 0.73028 -0.03947 -0.00681 -0.03528 4   SER A C   
4    O O   . SER A 4   ? 0.63061 0.71365 0.75381 -0.03564 -0.01144 -0.04068 4   SER A O   
5    C CB  . SER A 4   ? 0.80895 0.90896 1.01563 -0.04859 -0.01731 -0.03906 4   SER A CB  
6    O OG  . SER A 4   ? 0.73757 0.84317 0.92991 -0.04729 -0.03081 -0.05354 4   SER A OG  
11   N N   . ILE A 5   ? 0.53298 0.60116 0.67714 -0.04154 -0.00352 -0.03358 5   ILE A N   
12   C CA  . ILE A 5   ? 0.49756 0.55464 0.61419 -0.03884 -0.00408 -0.03725 5   ILE A CA  
13   C C   . ILE A 5   ? 0.44336 0.49608 0.53312 -0.03301 0.00429  -0.02937 5   ILE A C   
14   O O   . ILE A 5   ? 0.43928 0.48645 0.50613 -0.03025 0.00204  -0.03331 5   ILE A O   
15   C CB  . ILE A 5   ? 0.51242 0.55826 0.63901 -0.04205 -0.00269 -0.03581 5   ILE A CB  
16   C CG1 . ILE A 5   ? 0.55024 0.58753 0.65378 -0.03968 -0.00643 -0.04274 5   ILE A CG1 
17   C CG2 . ILE A 5   ? 0.69683 0.73817 0.82676 -0.04101 0.00971  -0.01957 5   ILE A CG2 
18   C CD1 . ILE A 5   ? 0.76508 0.79191 0.87963 -0.04215 -0.00716 -0.04372 5   ILE A CD1 
30   N N   . TRP A 6   ? 0.51988 0.57521 0.61330 -0.03077 0.01400  -0.01883 6   TRP A N   
31   C CA  . TRP A 6   ? 0.50379 0.55519 0.57241 -0.02454 0.02103  -0.01431 6   TRP A CA  
32   C C   . TRP A 6   ? 0.44811 0.50569 0.50836 -0.02152 0.01667  -0.01951 6   TRP A C   
33   O O   . TRP A 6   ? 0.50473 0.55627 0.54340 -0.01734 0.01801  -0.02035 6   TRP A O   
34   C CB  . TRP A 6   ? 0.42288 0.47649 0.49762 -0.02163 0.03367  -0.00250 6   TRP A CB  
35   C CG  . TRP A 6   ? 0.44224 0.48895 0.51775 -0.02229 0.04021  0.00621  6   TRP A CG  
36   C CD1 . TRP A 6   ? 0.47187 0.52156 0.57508 -0.02658 0.04345  0.01372  6   TRP A CD1 
37   C CD2 . TRP A 6   ? 0.46343 0.49982 0.51233 -0.01825 0.04372  0.00932  6   TRP A CD2 
38   N NE1 . TRP A 6   ? 0.52090 0.56283 0.61561 -0.02493 0.04980  0.02302  6   TRP A NE1 
39   C CE2 . TRP A 6   ? 0.46549 0.49982 0.52542 -0.01959 0.04952  0.02013  6   TRP A CE2 
40   C CE3 . TRP A 6   ? 0.44470 0.47381 0.46351 -0.01371 0.04176  0.00425  6   TRP A CE3 
41   C CZ2 . TRP A 6   ? 0.49837 0.52489 0.53713 -0.01575 0.05308  0.02647  6   TRP A CZ2 
42   C CZ3 . TRP A 6   ? 0.55450 0.57554 0.55359 -0.01063 0.04416  0.00855  6   TRP A CZ3 
43   C CH2 . TRP A 6   ? 0.62278 0.64315 0.63026 -0.01128 0.04960  0.01980  6   TRP A CH2 
54   N N   . SER A 7   ? 0.57195 0.64182 0.65062 -0.02351 0.01074  -0.02266 7   SER A N   
55   C CA  . SER A 7   ? 0.44206 0.51986 0.51486 -0.02010 0.00615  -0.02546 7   SER A CA  
56   C C   . SER A 7   ? 0.48144 0.55553 0.53510 -0.01927 -0.00110 -0.03256 7   SER A C   
57   O O   . SER A 7   ? 0.47665 0.55607 0.52250 -0.01568 -0.00396 -0.03288 7   SER A O   
58   C CB  . SER A 7   ? 0.44681 0.54055 0.54436 -0.02246 -0.00064 -0.02724 7   SER A CB  
59   O OG  . SER A 7   ? 0.47914 0.57674 0.58070 -0.02633 -0.01249 -0.03752 7   SER A OG  
65   N N   . ARG A 8   ? 0.49806 0.56380 0.54631 -0.02213 -0.00335 -0.03690 8   ARG A N   
66   C CA  . ARG A 8   ? 0.43023 0.49258 0.46219 -0.02103 -0.00841 -0.04271 8   ARG A CA  
67   C C   . ARG A 8   ? 0.43913 0.48996 0.45228 -0.01824 -0.00333 -0.03888 8   ARG A C   
68   O O   . ARG A 8   ? 0.43238 0.48199 0.43399 -0.01655 -0.00624 -0.04125 8   ARG A O   
69   C CB  . ARG A 8   ? 0.45076 0.51026 0.48923 -0.02490 -0.01354 -0.05025 8   ARG A CB  
70   C CG  . ARG A 8   ? 0.50612 0.57612 0.56488 -0.02816 -0.02098 -0.05733 8   ARG A CG  
71   C CD  . ARG A 8   ? 0.50411 0.56763 0.57588 -0.03251 -0.02407 -0.06404 8   ARG A CD  
72   N NE  . ARG A 8   ? 0.53582 0.59867 0.59537 -0.03067 -0.02990 -0.07451 8   ARG A NE  
73   C CZ  . ARG A 8   ? 0.44832 0.51671 0.51613 -0.03178 -0.03879 -0.08757 8   ARG A CZ  
74   N NH1 . ARG A 8   ? 0.50447 0.57844 0.59622 -0.03607 -0.04454 -0.09252 8   ARG A NH1 
75   N NH2 . ARG A 8   ? 0.68422 0.75285 0.73689 -0.02822 -0.04199 -0.09637 8   ARG A NH2 
89   N N   . ILE A 9   ? 0.51398 0.55734 0.52424 -0.01733 0.00399  -0.03309 9   ILE A N   
90   C CA  . ILE A 9   ? 0.49085 0.52385 0.48324 -0.01427 0.00722  -0.03123 9   ILE A CA  
91   C C   . ILE A 9   ? 0.48680 0.52183 0.47616 -0.00993 0.01022  -0.02926 9   ILE A C   
92   O O   . ILE A 9   ? 0.48424 0.52427 0.48218 -0.00816 0.01526  -0.02578 9   ILE A O   
93   C CB  . ILE A 9   ? 0.40267 0.42741 0.38995 -0.01409 0.01294  -0.02686 9   ILE A CB  
94   C CG1 . ILE A 9   ? 0.41161 0.43303 0.40378 -0.01794 0.00964  -0.02767 9   ILE A CG1 
95   C CG2 . ILE A 9   ? 0.58747 0.60274 0.55530 -0.01013 0.01486  -0.02692 9   ILE A CG2 
96   C CD1 . ILE A 9   ? 0.48492 0.50626 0.48898 -0.01954 0.01511  -0.02097 9   ILE A CD1 
108  N N   . VAL A 10  ? 0.52037 0.55182 0.50080 -0.00805 0.00759  -0.03075 10  VAL A N   
109  C CA  . VAL A 10  ? 0.51650 0.54931 0.49795 -0.00392 0.00961  -0.02863 10  VAL A CA  
110  C C   . VAL A 10  ? 0.53087 0.55085 0.50086 -0.00189 0.01037  -0.03030 10  VAL A C   
111  O O   . VAL A 10  ? 0.57579 0.58983 0.53889 -0.00406 0.00649  -0.03256 10  VAL A O   
112  C CB  . VAL A 10  ? 0.48669 0.53089 0.47482 -0.00333 0.00468  -0.02726 10  VAL A CB  
113  C CG1 . VAL A 10  ? 0.52654 0.57335 0.52036 0.00141  0.00745  -0.02260 10  VAL A CG1 
114  C CG2 . VAL A 10  ? 0.64292 0.69949 0.64090 -0.00591 0.00083  -0.02892 10  VAL A CG2 
124  N N   . ASN A 11  ? 0.64536 0.66099 0.61509 0.00244  0.01506  -0.02996 11  ASN A N   
125  C CA  . ASN A 11  ? 0.63038 0.63416 0.59385 0.00464  0.01423  -0.03319 11  ASN A CA  
126  C C   . ASN A 11  ? 0.53725 0.54289 0.50690 0.00286  0.00882  -0.03097 11  ASN A C   
127  O O   . ASN A 11  ? 0.54041 0.55598 0.52013 0.00403  0.00865  -0.02567 11  ASN A O   
128  C CB  . ASN A 11  ? 0.65266 0.65340 0.62018 0.01038  0.02023  -0.03346 11  ASN A CB  
129  C CG  . ASN A 11  ? 0.76796 0.75842 0.73836 0.01241  0.01807  -0.03610 11  ASN A CG  
130  O OD1 . ASN A 11  ? 0.88201 0.86460 0.84769 0.00970  0.01262  -0.03956 11  ASN A OD1 
131  N ND2 . ASN A 11  ? 0.95019 0.94089 0.93190 0.01712  0.02213  -0.03389 11  ASN A ND2 
138  N N   . PHE A 12  ? 0.56601 0.56360 0.53022 0.00049  0.00452  -0.03393 12  PHE A N   
139  C CA  . PHE A 12  ? 0.53263 0.53144 0.50454 -0.00090 0.00081  -0.03063 12  PHE A CA  
140  C C   . PHE A 12  ? 0.51946 0.50441 0.49028 -0.00156 -0.00253 -0.03545 12  PHE A C   
141  O O   . PHE A 12  ? 0.52550 0.50424 0.48600 -0.00336 -0.00573 -0.04077 12  PHE A O   
142  C CB  . PHE A 12  ? 0.47300 0.48023 0.44346 -0.00404 -0.00202 -0.02909 12  PHE A CB  
143  C CG  . PHE A 12  ? 0.41227 0.42746 0.39108 -0.00355 -0.00286 -0.02280 12  PHE A CG  
144  C CD1 . PHE A 12  ? 0.37070 0.39694 0.35534 -0.00040 -0.00083 -0.01657 12  PHE A CD1 
145  C CD2 . PHE A 12  ? 0.47971 0.49298 0.46112 -0.00556 -0.00528 -0.02180 12  PHE A CD2 
146  C CE1 . PHE A 12  ? 0.32367 0.35909 0.31393 0.00137  -0.00050 -0.00880 12  PHE A CE1 
147  C CE2 . PHE A 12  ? 0.47743 0.49989 0.46687 -0.00409 -0.00401 -0.01401 12  PHE A CE2 
148  C CZ  . PHE A 12  ? 0.32290 0.35654 0.31535 -0.00031 -0.00128 -0.00722 12  PHE A CZ  
158  N N   . GLY A 13  ? 0.46978 0.44990 0.45260 0.00007  -0.00246 -0.03362 13  GLY A N   
159  C CA  . GLY A 13  ? 0.39515 0.36154 0.38105 -0.00106 -0.00724 -0.03982 13  GLY A CA  
160  C C   . GLY A 13  ? 0.44309 0.39906 0.41215 0.00055  -0.00862 -0.05092 13  GLY A C   
161  O O   . GLY A 13  ? 0.47604 0.43209 0.43648 0.00461  -0.00300 -0.05321 13  GLY A O   
165  N N   . SER A 14  ? 0.47995 0.42819 0.44434 -0.00206 -0.01613 -0.05733 14  SER A N   
166  C CA  . SER A 14  ? 0.55191 0.49162 0.49668 0.00019  -0.01902 -0.06783 14  SER A CA  
167  C C   . SER A 14  ? 0.63557 0.58253 0.56323 0.00015  -0.01675 -0.06505 14  SER A C   
168  O O   . SER A 14  ? 0.66287 0.60527 0.57226 0.00235  -0.01908 -0.07097 14  SER A O   
169  C CB  . SER A 14  ? 0.54720 0.47738 0.49493 -0.00258 -0.03010 -0.07567 14  SER A CB  
170  O OG  . SER A 14  ? 0.61276 0.54948 0.56895 -0.00783 -0.03499 -0.06937 14  SER A OG  
176  N N   . GLY A 15  ? 0.55936 0.51756 0.49292 -0.00189 -0.01259 -0.05623 15  GLY A N   
177  C CA  . GLY A 15  ? 0.57701 0.54133 0.50040 -0.00260 -0.01049 -0.05296 15  GLY A CA  
178  C C   . GLY A 15  ? 0.55567 0.53086 0.48724 -0.00300 -0.00424 -0.04643 15  GLY A C   
179  O O   . GLY A 15  ? 0.48831 0.46594 0.42500 -0.00021 0.00093  -0.04532 15  GLY A O   
183  N N   . TRP A 16  ? 0.52761 0.50956 0.46193 -0.00617 -0.00528 -0.04274 16  TRP A N   
184  C CA  . TRP A 16  ? 0.47703 0.46904 0.41821 -0.00673 -0.00094 -0.03887 16  TRP A CA  
185  C C   . TRP A 16  ? 0.49941 0.49871 0.44892 -0.00975 -0.00424 -0.03730 16  TRP A C   
186  O O   . TRP A 16  ? 0.51245 0.50924 0.46233 -0.01132 -0.00841 -0.03785 16  TRP A O   
187  C CB  . TRP A 16  ? 0.55553 0.54793 0.49092 -0.00636 0.00313  -0.03721 16  TRP A CB  
188  C CG  . TRP A 16  ? 0.50979 0.49655 0.43362 -0.00180 0.00800  -0.03848 16  TRP A CG  
189  C CD1 . TRP A 16  ? 0.48577 0.46389 0.39371 0.00060  0.00588  -0.04198 16  TRP A CD1 
190  C CD2 . TRP A 16  ? 0.53003 0.52048 0.45671 0.00185  0.01582  -0.03681 16  TRP A CD2 
191  N NE1 . TRP A 16  ? 0.55999 0.53578 0.45798 0.00618  0.01254  -0.04353 16  TRP A NE1 
192  C CE2 . TRP A 16  ? 0.50006 0.48329 0.41062 0.00705  0.01951  -0.03982 16  TRP A CE2 
193  C CE3 . TRP A 16  ? 0.49992 0.50013 0.44159 0.00169  0.01969  -0.03323 16  TRP A CE3 
194  C CZ2 . TRP A 16  ? 0.50424 0.48930 0.41363 0.01256  0.02867  -0.03908 16  TRP A CZ2 
195  C CZ3 . TRP A 16  ? 0.45118 0.45360 0.39448 0.00641  0.02784  -0.03159 16  TRP A CZ3 
196  C CH2 . TRP A 16  ? 0.49581 0.49053 0.42327 0.01199  0.03314  -0.03432 16  TRP A CH2 
207  N N   . GLY A 17  ? 0.47988 0.48913 0.43663 -0.01003 -0.00247 -0.03588 17  GLY A N   
208  C CA  . GLY A 17  ? 0.38403 0.40132 0.34613 -0.01163 -0.00524 -0.03654 17  GLY A CA  
209  C C   . GLY A 17  ? 0.42348 0.44800 0.39194 -0.01294 -0.00469 -0.03803 17  GLY A C   
210  O O   . GLY A 17  ? 0.48714 0.51332 0.45905 -0.01243 -0.00156 -0.03644 17  GLY A O   
214  N N   . PHE A 18  ? 0.44755 0.47648 0.41964 -0.01447 -0.00774 -0.04162 18  PHE A N   
215  C CA  . PHE A 18  ? 0.39505 0.42880 0.37660 -0.01669 -0.00900 -0.04521 18  PHE A CA  
216  C C   . PHE A 18  ? 0.42498 0.47018 0.40872 -0.01553 -0.01334 -0.05059 18  PHE A C   
217  O O   . PHE A 18  ? 0.37959 0.42637 0.35746 -0.01366 -0.01446 -0.05230 18  PHE A O   
218  C CB  . PHE A 18  ? 0.39280 0.41834 0.37757 -0.01927 -0.00899 -0.04623 18  PHE A CB  
219  C CG  . PHE A 18  ? 0.47966 0.50808 0.47909 -0.02217 -0.01058 -0.05019 18  PHE A CG  
220  C CD1 . PHE A 18  ? 0.49086 0.52043 0.50087 -0.02402 -0.00767 -0.04647 18  PHE A CD1 
221  C CD2 . PHE A 18  ? 0.46616 0.49584 0.47109 -0.02286 -0.01462 -0.05784 18  PHE A CD2 
222  C CE1 . PHE A 18  ? 0.42829 0.46017 0.45720 -0.02755 -0.00972 -0.04984 18  PHE A CE1 
223  C CE2 . PHE A 18  ? 0.45569 0.48634 0.47732 -0.02590 -0.01714 -0.06321 18  PHE A CE2 
224  C CZ  . PHE A 18  ? 0.40791 0.43962 0.44304 -0.02877 -0.01517 -0.05896 18  PHE A CZ  
234  N N   . TRP A 19  ? 0.45308 0.50752 0.44525 -0.01608 -0.01583 -0.05308 19  TRP A N   
235  C CA  . TRP A 19  ? 0.42435 0.49173 0.41636 -0.01416 -0.02162 -0.05947 19  TRP A CA  
236  C C   . TRP A 19  ? 0.45616 0.52184 0.45537 -0.01672 -0.02572 -0.06976 19  TRP A C   
237  O O   . TRP A 19  ? 0.43740 0.50322 0.45177 -0.02046 -0.02831 -0.07353 19  TRP A O   
238  C CB  . TRP A 19  ? 0.44250 0.52160 0.44203 -0.01349 -0.02440 -0.05802 19  TRP A CB  
239  C CG  . TRP A 19  ? 0.44338 0.52741 0.43668 -0.00921 -0.02178 -0.04923 19  TRP A CG  
240  C CD1 . TRP A 19  ? 0.42416 0.50502 0.42236 -0.00871 -0.01702 -0.04190 19  TRP A CD1 
241  C CD2 . TRP A 19  ? 0.40131 0.49428 0.38409 -0.00414 -0.02293 -0.04608 19  TRP A CD2 
242  N NE1 . TRP A 19  ? 0.47001 0.55581 0.46357 -0.00411 -0.01583 -0.03508 19  TRP A NE1 
243  C CE2 . TRP A 19  ? 0.47169 0.56532 0.45624 -0.00140 -0.01923 -0.03621 19  TRP A CE2 
244  C CE3 . TRP A 19  ? 0.47401 0.57488 0.44645 -0.00089 -0.02576 -0.04997 19  TRP A CE3 
245  C CZ2 . TRP A 19  ? 0.45397 0.55546 0.43283 0.00381  -0.01853 -0.02852 19  TRP A CZ2 
246  C CZ3 . TRP A 19  ? 0.52040 0.63065 0.48455 0.00483  -0.02426 -0.04179 19  TRP A CZ3 
247  C CH2 . TRP A 19  ? 0.41704 0.52742 0.38566 0.00681  -0.02085 -0.03039 19  TRP A CH2 
258  N N   . VAL A 20  ? 0.55860 0.62250 0.54976 -0.01452 -0.02588 -0.07418 20  VAL A N   
259  C CA  . VAL A 20  ? 0.54217 0.60327 0.54095 -0.01590 -0.02943 -0.08539 20  VAL A CA  
260  C C   . VAL A 20  ? 0.55910 0.63271 0.56056 -0.01473 -0.03733 -0.09691 20  VAL A C   
261  O O   . VAL A 20  ? 0.63751 0.70894 0.65433 -0.01820 -0.04235 -0.10667 20  VAL A O   
262  C CB  . VAL A 20  ? 0.52231 0.57937 0.51244 -0.01261 -0.02657 -0.08697 20  VAL A CB  
263  C CG1 . VAL A 20  ? 0.59878 0.65270 0.59759 -0.01280 -0.02988 -0.10004 20  VAL A CG1 
264  C CG2 . VAL A 20  ? 0.62117 0.66649 0.61088 -0.01433 -0.02124 -0.07653 20  VAL A CG2 
274  N N   . SER A 21  ? 0.50150 0.58878 0.48941 -0.00971 -0.03920 -0.09564 21  SER A N   
275  C CA  . SER A 21  ? 0.50753 0.60988 0.49247 -0.00682 -0.04796 -0.10614 21  SER A CA  
276  C C   . SER A 21  ? 0.51607 0.63136 0.49589 -0.00416 -0.04909 -0.09641 21  SER A C   
277  O O   . SER A 21  ? 0.61555 0.72635 0.59433 -0.00428 -0.04224 -0.08281 21  SER A O   
278  C CB  . SER A 21  ? 0.50789 0.61628 0.47600 -0.00012 -0.04850 -0.11511 21  SER A CB  
279  O OG  . SER A 21  ? 0.65751 0.77475 0.60789 0.00625  -0.04310 -0.10400 21  SER A OG  
285  N N   . PRO A 22  ? 0.46899 0.60050 0.44620 -0.00126 -0.05825 -0.10332 22  PRO A N   
286  C CA  . PRO A 22  ? 0.44958 0.59525 0.42026 0.00314  -0.05908 -0.09218 22  PRO A CA  
287  C C   . PRO A 22  ? 0.53705 0.68463 0.49010 0.00941  -0.05073 -0.07969 22  PRO A C   
288  O O   . PRO A 22  ? 0.53681 0.69002 0.48974 0.01190  -0.04815 -0.06637 22  PRO A O   
289  C CB  . PRO A 22  ? 0.53437 0.69865 0.50058 0.00668  -0.07191 -0.10422 22  PRO A CB  
290  C CG  . PRO A 22  ? 0.52071 0.67705 0.50295 0.00046  -0.07874 -0.12182 22  PRO A CG  
291  C CD  . PRO A 22  ? 0.50321 0.64094 0.48459 -0.00164 -0.06924 -0.12200 22  PRO A CD  
299  N N   . SER A 23  ? 0.65123 0.79482 0.59234 0.01231  -0.04612 -0.08285 23  SER A N   
300  C CA  . SER A 23  ? 0.54137 0.68853 0.46980 0.01818  -0.03791 -0.06983 23  SER A CA  
301  C C   . SER A 23  ? 0.50344 0.63386 0.43617 0.01509  -0.02896 -0.06435 23  SER A C   
302  O O   . SER A 23  ? 0.51812 0.65015 0.44604 0.01869  -0.02209 -0.05244 23  SER A O   
303  C CB  . SER A 23  ? 0.57250 0.73574 0.48107 0.02704  -0.03921 -0.07511 23  SER A CB  
304  O OG  . SER A 23  ? 0.72770 0.90199 0.63276 0.02827  -0.05075 -0.09040 23  SER A OG  
310  N N   . LEU A 24  ? 0.51513 0.63039 0.45861 0.00866  -0.02918 -0.07140 24  LEU A N   
311  C CA  . LEU A 24  ? 0.41013 0.51169 0.35625 0.00661  -0.02274 -0.06825 24  LEU A CA  
312  C C   . LEU A 24  ? 0.40866 0.49590 0.36544 0.00056  -0.02055 -0.06157 24  LEU A C   
313  O O   . LEU A 24  ? 0.44650 0.52664 0.41260 -0.00425 -0.02308 -0.06657 24  LEU A O   
314  C CB  . LEU A 24  ? 0.43457 0.53116 0.38240 0.00605  -0.02434 -0.08154 24  LEU A CB  
315  C CG  . LEU A 24  ? 0.43180 0.51752 0.38255 0.00544  -0.01821 -0.07777 24  LEU A CG  
316  C CD1 . LEU A 24  ? 0.61770 0.71118 0.56046 0.01082  -0.01185 -0.06686 24  LEU A CD1 
317  C CD2 . LEU A 24  ? 0.57759 0.65877 0.53199 0.00609  -0.01921 -0.09051 24  LEU A CD2 
329  N N   . PHE A 25  ? 0.51497 0.59841 0.47097 0.00127  -0.01568 -0.05033 25  PHE A N   
330  C CA  . PHE A 25  ? 0.41224 0.48221 0.37451 -0.00290 -0.01351 -0.04515 25  PHE A CA  
331  C C   . PHE A 25  ? 0.40526 0.46466 0.36851 -0.00454 -0.01122 -0.04441 25  PHE A C   
332  O O   . PHE A 25  ? 0.51330 0.57679 0.47476 -0.00167 -0.00886 -0.04128 25  PHE A O   
333  C CB  . PHE A 25  ? 0.49105 0.56335 0.45410 -0.00071 -0.01111 -0.03502 25  PHE A CB  
334  C CG  . PHE A 25  ? 0.39497 0.45577 0.36297 -0.00359 -0.00965 -0.03269 25  PHE A CG  
335  C CD1 . PHE A 25  ? 0.45876 0.51921 0.43079 -0.00559 -0.01078 -0.03609 25  PHE A CD1 
336  C CD2 . PHE A 25  ? 0.38480 0.43600 0.35442 -0.00377 -0.00702 -0.02737 25  PHE A CD2 
337  C CE1 . PHE A 25  ? 0.45559 0.50687 0.43019 -0.00669 -0.00775 -0.03374 25  PHE A CE1 
338  C CE2 . PHE A 25  ? 0.40845 0.44947 0.37967 -0.00504 -0.00566 -0.02731 25  PHE A CE2 
339  C CZ  . PHE A 25  ? 0.49775 0.53931 0.47003 -0.00592 -0.00525 -0.03015 25  PHE A CZ  
349  N N   . ILE A 26  ? 0.38822 0.43554 0.35509 -0.00862 -0.01173 -0.04619 26  ILE A N   
350  C CA  . ILE A 26  ? 0.39933 0.43722 0.36763 -0.01006 -0.01110 -0.04450 26  ILE A CA  
351  C C   . ILE A 26  ? 0.41000 0.43747 0.37738 -0.01218 -0.01102 -0.04050 26  ILE A C   
352  O O   . ILE A 26  ? 0.48986 0.51493 0.45618 -0.01314 -0.01045 -0.04083 26  ILE A O   
353  C CB  . ILE A 26  ? 0.44649 0.48011 0.41872 -0.01163 -0.01248 -0.05055 26  ILE A CB  
354  C CG1 . ILE A 26  ? 0.50016 0.52731 0.47586 -0.01496 -0.01333 -0.05190 26  ILE A CG1 
355  C CG2 . ILE A 26  ? 0.40581 0.44924 0.37778 -0.00853 -0.01281 -0.05761 26  ILE A CG2 
356  C CD1 . ILE A 26  ? 0.40038 0.42176 0.38389 -0.01658 -0.01431 -0.05562 26  ILE A CD1 
368  N N   . THR A 27  ? 0.33881 0.36064 0.30729 -0.01255 -0.01172 -0.03728 27  THR A N   
369  C CA  . THR A 27  ? 0.40210 0.41396 0.36790 -0.01377 -0.01306 -0.03583 27  THR A CA  
370  C C   . THR A 27  ? 0.45446 0.46064 0.42352 -0.01507 -0.01665 -0.03489 27  THR A C   
371  O O   . THR A 27  ? 0.44647 0.45663 0.42127 -0.01494 -0.01690 -0.03432 27  THR A O   
372  C CB  . THR A 27  ? 0.45743 0.47033 0.42468 -0.01212 -0.01136 -0.03277 27  THR A CB  
373  O OG1 . THR A 27  ? 0.43640 0.43831 0.40065 -0.01266 -0.01311 -0.03412 27  THR A OG1 
374  C CG2 . THR A 27  ? 0.38049 0.39994 0.35589 -0.01069 -0.01035 -0.02743 27  THR A CG2 
382  N N   . SER A 28  ? 0.51998 0.51741 0.48617 -0.01584 -0.01980 -0.03542 28  SER A N   
383  C CA  . SER A 28  ? 0.47150 0.46390 0.44210 -0.01737 -0.02556 -0.03535 28  SER A CA  
384  C C   . SER A 28  ? 0.51764 0.51029 0.50049 -0.01786 -0.02661 -0.03274 28  SER A C   
385  O O   . SER A 28  ? 0.62430 0.61450 0.60756 -0.01697 -0.02487 -0.03280 28  SER A O   
386  C CB  . SER A 28  ? 0.51431 0.49731 0.47315 -0.01746 -0.03020 -0.03900 28  SER A CB  
387  O OG  . SER A 28  ? 0.61170 0.59031 0.57531 -0.01890 -0.03811 -0.04025 28  SER A OG  
393  N N   . THR A 29  ? 0.39418 0.38973 0.39004 -0.01917 -0.02916 -0.02961 29  THR A N   
394  C CA  . THR A 29  ? 0.42529 0.42207 0.43852 -0.02012 -0.02953 -0.02494 29  THR A CA  
395  C C   . THR A 29  ? 0.47450 0.45977 0.48924 -0.02174 -0.03552 -0.02974 29  THR A C   
396  O O   . THR A 29  ? 0.42973 0.41372 0.45656 -0.02174 -0.03367 -0.02663 29  THR A O   
397  C CB  . THR A 29  ? 0.56950 0.57126 0.59900 -0.02153 -0.03188 -0.02076 29  THR A CB  
398  O OG1 . THR A 29  ? 0.45122 0.46330 0.47921 -0.01880 -0.02539 -0.01780 29  THR A OG1 
399  C CG2 . THR A 29  ? 0.69381 0.69762 0.74653 -0.02302 -0.03172 -0.01402 29  THR A CG2 
407  N N   . HIS A 30  ? 0.59701 0.57387 0.59992 -0.02251 -0.04274 -0.03733 30  HIS A N   
408  C CA  . HIS A 30  ? 0.57560 0.54114 0.57740 -0.02308 -0.04935 -0.04486 30  HIS A CA  
409  C C   . HIS A 30  ? 0.48911 0.45029 0.48261 -0.02017 -0.04346 -0.04740 30  HIS A C   
410  O O   . HIS A 30  ? 0.60218 0.55340 0.59768 -0.01981 -0.04742 -0.05420 30  HIS A O   
411  C CB  . HIS A 30  ? 0.73613 0.69567 0.72133 -0.02280 -0.05812 -0.05258 30  HIS A CB  
412  C CG  . HIS A 30  ? 0.74519 0.70375 0.74419 -0.02605 -0.06959 -0.05425 30  HIS A CG  
413  N ND1 . HIS A 30  ? 0.90820 0.85798 0.90220 -0.02647 -0.08138 -0.06443 30  HIS A ND1 
414  C CD2 . HIS A 30  ? 0.84938 0.81564 0.86836 -0.02869 -0.07139 -0.04734 30  HIS A CD2 
415  C CE1 . HIS A 30  ? 0.85626 0.80866 0.86816 -0.02998 -0.09129 -0.06354 30  HIS A CE1 
416  N NE2 . HIS A 30  ? 0.89802 0.86056 0.92637 -0.03134 -0.08469 -0.05244 30  HIS A NE2 
424  N N   . VAL A 31  ? 0.59348 0.56177 0.57903 -0.01785 -0.03481 -0.04305 31  VAL A N   
425  C CA  . VAL A 31  ? 0.53284 0.49880 0.51070 -0.01461 -0.02914 -0.04481 31  VAL A CA  
426  C C   . VAL A 31  ? 0.56124 0.53274 0.55414 -0.01345 -0.02343 -0.03724 31  VAL A C   
427  O O   . VAL A 31  ? 0.60879 0.57664 0.60184 -0.01068 -0.02007 -0.03833 31  VAL A O   
428  C CB  . VAL A 31  ? 0.53540 0.50640 0.49684 -0.01286 -0.02434 -0.04469 31  VAL A CB  
429  C CG1 . VAL A 31  ? 0.64675 0.62018 0.60619 -0.00970 -0.01734 -0.04351 31  VAL A CG1 
430  C CG2 . VAL A 31  ? 0.55458 0.51894 0.49947 -0.01224 -0.02847 -0.05065 31  VAL A CG2 
440  N N   . ILE A 32  ? 0.52906 0.50997 0.53465 -0.01461 -0.02171 -0.02880 32  ILE A N   
441  C CA  . ILE A 32  ? 0.45628 0.44612 0.47203 -0.01211 -0.01530 -0.01919 32  ILE A CA  
442  C C   . ILE A 32  ? 0.53437 0.51574 0.56791 -0.01200 -0.01599 -0.01705 32  ILE A C   
443  O O   . ILE A 32  ? 0.53599 0.50930 0.58270 -0.01524 -0.02164 -0.01950 32  ILE A O   
444  C CB  . ILE A 32  ? 0.53350 0.53669 0.55612 -0.01201 -0.01232 -0.01043 32  ILE A CB  
445  C CG1 . ILE A 32  ? 0.61908 0.62952 0.62539 -0.01136 -0.01137 -0.01432 32  ILE A CG1 
446  C CG2 . ILE A 32  ? 0.57842 0.59109 0.61245 -0.00863 -0.00619 0.00155  32  ILE A CG2 
447  C CD1 . ILE A 32  ? 0.87743 0.90229 0.88482 -0.00908 -0.00708 -0.00846 32  ILE A CD1 
459  N N   . PRO A 33  ? 0.50011 0.48223 0.53724 -0.00847 -0.01128 -0.01306 33  PRO A N   
460  C CA  . PRO A 33  ? 0.45067 0.42379 0.50933 -0.00805 -0.01138 -0.01002 33  PRO A CA  
461  C C   . PRO A 33  ? 0.48587 0.46690 0.56735 -0.00905 -0.00890 0.00428  33  PRO A C   
462  O O   . PRO A 33  ? 0.63443 0.63109 0.71419 -0.00614 -0.00290 0.01596  33  PRO A O   
463  C CB  . PRO A 33  ? 0.50561 0.48059 0.56165 -0.00295 -0.00583 -0.00740 33  PRO A CB  
464  C CG  . PRO A 33  ? 0.47088 0.45394 0.50290 -0.00162 -0.00427 -0.01204 33  PRO A CG  
465  C CD  . PRO A 33  ? 0.42003 0.41147 0.44499 -0.00468 -0.00622 -0.01088 33  PRO A CD  
473  N N   . GLN A 34  ? 0.53568 0.50675 0.63936 -0.01281 -0.01356 0.00350  34  GLN A N   
474  C CA  . GLN A 34  ? 0.52794 0.50688 0.65704 -0.01445 -0.01082 0.01803  34  GLN A CA  
475  C C   . GLN A 34  ? 0.54739 0.52588 0.70277 -0.01203 -0.00525 0.03188  34  GLN A C   
476  O O   . GLN A 34  ? 0.60303 0.58990 0.78173 -0.01239 -0.00069 0.04773  34  GLN A O   
477  C CB  . GLN A 34  ? 0.53939 0.50953 0.68418 -0.02063 -0.01968 0.01117  34  GLN A CB  
478  C CG  . GLN A 34  ? 0.53212 0.50461 0.65564 -0.02266 -0.02503 0.00132  34  GLN A CG  
479  C CD  . GLN A 34  ? 0.71773 0.70808 0.83763 -0.02113 -0.01838 0.01230  34  GLN A CD  
480  O OE1 . GLN A 34  ? 0.69210 0.68901 0.83384 -0.02303 -0.01712 0.02161  34  GLN A OE1 
481  N NE2 . GLN A 34  ? 0.67667 0.67535 0.77085 -0.01730 -0.01374 0.01110  34  GLN A NE2 
490  N N   . GLY A 35  ? 0.57287 0.54216 0.72682 -0.00905 -0.00473 0.02742  35  GLY A N   
491  C CA  . GLY A 35  ? 0.63076 0.59820 0.81111 -0.00607 0.00046  0.04072  35  GLY A CA  
492  C C   . GLY A 35  ? 0.60099 0.58253 0.76900 0.00098  0.00823  0.05206  35  GLY A C   
493  O O   . GLY A 35  ? 0.63343 0.61416 0.82088 0.00482  0.01272  0.06373  35  GLY A O   
497  N N   . THR A 36  ? 0.69879 0.69369 0.83702 0.00280  0.00920  0.04919  36  THR A N   
498  C CA  . THR A 36  ? 0.68144 0.69061 0.80542 0.00903  0.01383  0.05640  36  THR A CA  
499  C C   . THR A 36  ? 0.63116 0.66234 0.75137 0.01243  0.01911  0.07289  36  THR A C   
500  O O   . THR A 36  ? 0.64055 0.67729 0.75601 0.00990  0.01904  0.07250  36  THR A O   
501  C CB  . THR A 36  ? 0.68878 0.69767 0.78413 0.00872  0.01050  0.04046  36  THR A CB  
502  O OG1 . THR A 36  ? 0.77238 0.76297 0.86920 0.00781  0.00762  0.02690  36  THR A OG1 
503  C CG2 . THR A 36  ? 0.93844 0.96433 1.02068 0.01415  0.01341  0.04685  36  THR A CG2 
511  N N   . GLN A 37  ? 0.56269 0.60718 0.68452 0.01908  0.02376  0.08741  37  GLN A N   
512  C CA  . GLN A 37  ? 0.58162 0.64872 0.69832 0.02442  0.02930  0.10461  37  GLN A CA  
513  C C   . GLN A 37  ? 0.52425 0.60886 0.61397 0.02971  0.02792  0.10268  37  GLN A C   
514  O O   . GLN A 37  ? 0.55974 0.66499 0.64014 0.03570  0.03155  0.11529  37  GLN A O   
515  C CB  . GLN A 37  ? 0.50975 0.58053 0.65506 0.02870  0.03592  0.12790  37  GLN A CB  
516  C CG  . GLN A 37  ? 0.57396 0.62370 0.75334 0.02297  0.03549  0.12798  37  GLN A CG  
517  C CD  . GLN A 37  ? 0.63543 0.69007 0.84783 0.02672  0.04321  0.15387  37  GLN A CD  
518  O OE1 . GLN A 37  ? 0.75945 0.83176 0.96844 0.03473  0.04877  0.17228  37  GLN A OE1 
519  N NE2 . GLN A 37  ? 0.80095 0.84068 1.04692 0.02105  0.04310  0.15608  37  GLN A NE2 
528  N N   . GLU A 38  ? 0.53796 0.61578 0.61527 0.02789  0.02263  0.08702  38  GLU A N   
529  C CA  . GLU A 38  ? 0.60125 0.69449 0.65603 0.03111  0.01942  0.08205  38  GLU A CA  
530  C C   . GLU A 38  ? 0.56467 0.64649 0.60694 0.02549  0.01430  0.06136  38  GLU A C   
531  O O   . GLU A 38  ? 0.50753 0.57133 0.55814 0.02202  0.01360  0.05332  38  GLU A O   
532  C CB  . GLU A 38  ? 0.62441 0.72751 0.68525 0.03757  0.01968  0.09293  38  GLU A CB  
533  C CG  . GLU A 38  ? 0.62710 0.71284 0.70580 0.03656  0.01994  0.08962  38  GLU A CG  
534  C CD  . GLU A 38  ? 0.89071 0.98709 0.96763 0.04147  0.01775  0.09147  38  GLU A CD  
535  O OE1 . GLU A 38  ? 0.87124 0.97341 0.93158 0.03966  0.01313  0.07908  38  GLU A OE1 
536  O OE2 . GLU A 38  ? 1.00073 1.10034 1.09526 0.04710  0.02046  0.10601  38  GLU A OE2 
543  N N   . PHE A 39  ? 0.58869 0.68117 0.61134 0.02517  0.01094  0.05288  39  PHE A N   
544  C CA  . PHE A 39  ? 0.49489 0.57891 0.50739 0.02027  0.00679  0.03590  39  PHE A CA  
545  C C   . PHE A 39  ? 0.49291 0.59173 0.49653 0.02298  0.00290  0.03319  39  PHE A C   
546  O O   . PHE A 39  ? 0.56009 0.67620 0.55348 0.02659  0.00088  0.03593  39  PHE A O   
547  C CB  . PHE A 39  ? 0.52835 0.60849 0.53106 0.01598  0.00560  0.02677  39  PHE A CB  
548  C CG  . PHE A 39  ? 0.53678 0.60113 0.54967 0.01194  0.00704  0.02625  39  PHE A CG  
549  C CD1 . PHE A 39  ? 0.46156 0.50893 0.48394 0.00947  0.00644  0.02227  39  PHE A CD1 
550  C CD2 . PHE A 39  ? 0.43078 0.49813 0.44419 0.01108  0.00857  0.02888  39  PHE A CD2 
551  C CE1 . PHE A 39  ? 0.52822 0.56175 0.56023 0.00561  0.00548  0.01996  39  PHE A CE1 
552  C CE2 . PHE A 39  ? 0.49580 0.55038 0.52148 0.00698  0.00838  0.02843  39  PHE A CE2 
553  C CZ  . PHE A 39  ? 0.52566 0.56323 0.56066 0.00391  0.00588  0.02350  39  PHE A CZ  
563  N N   . PHE A 40  ? 0.61780 0.71072 0.62606 0.02175  0.00176  0.02767  40  PHE A N   
564  C CA  . PHE A 40  ? 0.63697 0.74361 0.64306 0.02355  -0.00257 0.02531  40  PHE A CA  
565  C C   . PHE A 40  ? 0.67472 0.80112 0.68210 0.03055  -0.00426 0.03838  40  PHE A C   
566  O O   . PHE A 40  ? 0.56594 0.70967 0.56441 0.03265  -0.01031 0.03605  40  PHE A O   
567  C CB  . PHE A 40  ? 0.51445 0.62510 0.50851 0.01958  -0.00747 0.01245  40  PHE A CB  
568  C CG  . PHE A 40  ? 0.50096 0.59416 0.49343 0.01350  -0.00579 0.00205  40  PHE A CG  
569  C CD1 . PHE A 40  ? 0.50696 0.59125 0.50604 0.01170  -0.00376 -0.00151 40  PHE A CD1 
570  C CD2 . PHE A 40  ? 0.47129 0.55823 0.45565 0.01050  -0.00572 -0.00308 40  PHE A CD2 
571  C CE1 . PHE A 40  ? 0.45351 0.52350 0.44870 0.00729  -0.00194 -0.00943 40  PHE A CE1 
572  C CE2 . PHE A 40  ? 0.47116 0.54354 0.45385 0.00566  -0.00490 -0.01100 40  PHE A CE2 
573  C CZ  . PHE A 40  ? 0.45176 0.51588 0.43865 0.00418  -0.00313 -0.01389 40  PHE A CZ  
583  N N   . GLY A 41  ? 0.61485 0.73874 0.63422 0.03450  0.00057  0.05230  41  GLY A N   
584  C CA  . GLY A 41  ? 0.54176 0.68423 0.56400 0.04215  0.00005  0.06835  41  GLY A CA  
585  C C   . GLY A 41  ? 0.53107 0.68797 0.53967 0.04591  0.00056  0.07565  41  GLY A C   
586  O O   . GLY A 41  ? 0.55446 0.72813 0.56353 0.05344  0.00110  0.09156  41  GLY A O   
590  N N   . VAL A 42  ? 0.66807 0.82008 0.66460 0.04188  0.00106  0.06564  42  VAL A N   
591  C CA  . VAL A 42  ? 0.55024 0.71626 0.53361 0.04647  0.00341  0.07218  42  VAL A CA  
592  C C   . VAL A 42  ? 0.62147 0.77638 0.61864 0.04540  0.01206  0.08335  42  VAL A C   
593  O O   . VAL A 42  ? 0.60996 0.74482 0.61603 0.03834  0.01317  0.07476  42  VAL A O   
594  C CB  . VAL A 42  ? 0.53366 0.70226 0.49814 0.04372  -0.00079 0.05460  42  VAL A CB  
595  C CG1 . VAL A 42  ? 0.52385 0.70910 0.47277 0.05048  0.00254  0.06071  42  VAL A CG1 
596  C CG2 . VAL A 42  ? 0.60642 0.78253 0.56391 0.04274  -0.01038 0.04158  42  VAL A CG2 
606  N N   . PRO A 43  ? 0.63940 0.80711 0.64001 0.05217  0.01802  0.10273  43  PRO A N   
607  C CA  . PRO A 43  ? 0.67864 0.83585 0.69794 0.05020  0.02618  0.11380  43  PRO A CA  
608  C C   . PRO A 43  ? 0.59754 0.74973 0.60878 0.04581  0.02762  0.10277  43  PRO A C   
609  O O   . PRO A 43  ? 0.57102 0.73602 0.56034 0.04868  0.02613  0.09510  43  PRO A O   
610  C CB  . PRO A 43  ? 0.66574 0.84282 0.68839 0.05979  0.03292  0.13890  43  PRO A CB  
611  C CG  . PRO A 43  ? 0.61253 0.80691 0.62197 0.06650  0.02699  0.14158  43  PRO A CG  
612  C CD  . PRO A 43  ? 0.61830 0.81114 0.60850 0.06220  0.01746  0.11706  43  PRO A CD  
620  N N   . THR A 44  ? 0.64984 0.78313 0.68019 0.03908  0.02982  0.10114  44  THR A N   
621  C CA  . THR A 44  ? 0.61186 0.73949 0.63840 0.03454  0.03038  0.09110  44  THR A CA  
622  C C   . THR A 44  ? 0.58245 0.72903 0.60239 0.04106  0.03803  0.10272  44  THR A C   
623  O O   . THR A 44  ? 0.56849 0.71818 0.57540 0.04070  0.03815  0.09240  44  THR A O   
624  C CB  . THR A 44  ? 0.57107 0.67741 0.62185 0.02690  0.03019  0.08941  44  THR A CB  
625  O OG1 . THR A 44  ? 0.58127 0.68755 0.65766 0.02891  0.03591  0.10873  44  THR A OG1 
626  C CG2 . THR A 44  ? 0.50152 0.58891 0.55165 0.02103  0.02282  0.07312  44  THR A CG2 
634  N N   . LYS A 45  ? 0.66630 0.82617 0.69557 0.04788  0.04532  0.12495  45  LYS A N   
635  C CA  . LYS A 45  ? 0.56026 0.74096 0.58122 0.05595  0.05451  0.13821  45  LYS A CA  
636  C C   . LYS A 45  ? 0.55981 0.75671 0.54553 0.06202  0.05133  0.12517  45  LYS A C   
637  O O   . LYS A 45  ? 0.57599 0.78353 0.55059 0.06630  0.05715  0.12420  45  LYS A O   
638  C CB  . LYS A 45  ? 0.66025 0.85521 0.69361 0.06383  0.06260  0.16597  45  LYS A CB  
639  C CG  . LYS A 45  ? 0.96064 1.15069 1.02877 0.06175  0.07225  0.18550  45  LYS A CG  
640  C CD  . LYS A 45  ? 0.91629 1.11487 1.00308 0.06793  0.07851  0.21272  45  LYS A CD  
641  C CE  . LYS A 45  ? 1.12811 1.32296 1.25401 0.06582  0.08872  0.23388  45  LYS A CE  
642  N NZ  . LYS A 45  ? 1.22418 1.44584 1.33932 0.07618  0.10168  0.25309  45  LYS A NZ  
656  N N   . GLN A 46  ? 0.64632 0.84510 0.61629 0.06251  0.04198  0.11412  46  GLN A N   
657  C CA  . GLN A 46  ? 0.63985 0.85217 0.57951 0.06716  0.03635  0.09863  46  GLN A CA  
658  C C   . GLN A 46  ? 0.55645 0.75333 0.49096 0.05910  0.02953  0.07348  46  GLN A C   
659  O O   . GLN A 46  ? 0.55415 0.75956 0.46728 0.06199  0.02431  0.05826  46  GLN A O   
660  C CB  . GLN A 46  ? 0.65143 0.87506 0.58002 0.07132  0.02811  0.09884  46  GLN A CB  
661  C CG  . GLN A 46  ? 0.64458 0.88671 0.57474 0.08097  0.03356  0.12412  46  GLN A CG  
662  C CD  . GLN A 46  ? 0.76786 1.02291 0.68739 0.08542  0.02376  0.12372  46  GLN A CD  
663  O OE1 . GLN A 46  ? 0.87031 1.12458 0.80686 0.08640  0.02399  0.13901  46  GLN A OE1 
664  N NE2 . GLN A 46  ? 0.96799 1.23474 0.86190 0.08807  0.01443  0.10564  46  GLN A NE2 
673  N N   . ILE A 47  ? 0.53607 0.71082 0.48981 0.04951  0.02883  0.06863  47  ILE A N   
674  C CA  . ILE A 47  ? 0.50797 0.66784 0.45863 0.04210  0.02277  0.04778  47  ILE A CA  
675  C C   . ILE A 47  ? 0.53684 0.69352 0.49182 0.04121  0.02863  0.04640  47  ILE A C   
676  O O   . ILE A 47  ? 0.59971 0.75253 0.57336 0.03990  0.03495  0.05948  47  ILE A O   
677  C CB  . ILE A 47  ? 0.41397 0.55311 0.37966 0.03335  0.01774  0.04287  47  ILE A CB  
678  C CG1 . ILE A 47  ? 0.46640 0.60995 0.43229 0.03530  0.01382  0.04715  47  ILE A CG1 
679  C CG2 . ILE A 47  ? 0.41619 0.54304 0.37649 0.02706  0.01194  0.02361  47  ILE A CG2 
680  C CD1 . ILE A 47  ? 0.56588 0.69052 0.54659 0.02880  0.01109  0.04398  47  ILE A CD1 
692  N N   . GLN A 48  ? 0.64373 0.80238 0.58440 0.04210  0.02644  0.03077  48  GLN A N   
693  C CA  . GLN A 48  ? 0.64213 0.79806 0.58749 0.04187  0.03171  0.02789  48  GLN A CA  
694  C C   . GLN A 48  ? 0.58216 0.71645 0.53977 0.03187  0.02580  0.01707  48  GLN A C   
695  O O   . GLN A 48  ? 0.59094 0.71827 0.54050 0.02866  0.01880  0.00167  48  GLN A O   
696  C CB  . GLN A 48  ? 0.75927 0.92738 0.68437 0.04896  0.03290  0.01576  48  GLN A CB  
697  C CG  . GLN A 48  ? 0.98371 1.17569 0.89162 0.06093  0.03959  0.02520  48  GLN A CG  
698  C CD  . GLN A 48  ? 1.11604 1.31801 1.00146 0.06813  0.03888  0.00805  48  GLN A CD  
699  O OE1 . GLN A 48  ? 1.08398 1.27583 0.97293 0.06529  0.03817  -0.00591 48  GLN A OE1 
700  N NE2 . GLN A 48  ? 1.09614 1.31809 0.95836 0.07800  0.03837  0.00840  48  GLN A NE2 
709  N N   . ILE A 49  ? 0.55588 0.68032 0.53380 0.02719  0.02824  0.02553  49  ILE A N   
710  C CA  . ILE A 49  ? 0.48282 0.58821 0.47110 0.01866  0.02217  0.01692  49  ILE A CA  
711  C C   . ILE A 49  ? 0.49272 0.59767 0.48882 0.01860  0.02519  0.01502  49  ILE A C   
712  O O   . ILE A 49  ? 0.57833 0.69070 0.58781 0.02113  0.03223  0.02705  49  ILE A O   
713  C CB  . ILE A 49  ? 0.45620 0.54976 0.46185 0.01329  0.02001  0.02482  49  ILE A CB  
714  C CG1 . ILE A 49  ? 0.42488 0.52236 0.42572 0.01566  0.01960  0.03015  49  ILE A CG1 
715  C CG2 . ILE A 49  ? 0.58850 0.66361 0.59738 0.00578  0.01224  0.01369  49  ILE A CG2 
716  C CD1 . ILE A 49  ? 0.34556 0.42936 0.36171 0.01109  0.01690  0.03417  49  ILE A CD1 
728  N N   . HIS A 50  ? 0.60068 0.69749 0.59124 0.01595  0.02036  0.00118  50  HIS A N   
729  C CA  . HIS A 50  ? 0.64041 0.73481 0.64047 0.01555  0.02191  -0.00142 50  HIS A CA  
730  C C   . HIS A 50  ? 0.59103 0.66816 0.60040 0.00756  0.01379  -0.00596 50  HIS A C   
731  O O   . HIS A 50  ? 0.56153 0.62929 0.56193 0.00406  0.00770  -0.01426 50  HIS A O   
732  C CB  . HIS A 50  ? 0.69768 0.79747 0.68506 0.02056  0.02349  -0.01347 50  HIS A CB  
733  C CG  . HIS A 50  ? 1.01040 1.11080 1.00951 0.02243  0.02752  -0.01396 50  HIS A CG  
734  N ND1 . HIS A 50  ? 0.96218 1.05001 0.96900 0.01798  0.02204  -0.02150 50  HIS A ND1 
735  C CD2 . HIS A 50  ? 1.01359 1.12675 1.01969 0.02892  0.03718  -0.00638 50  HIS A CD2 
736  C CE1 . HIS A 50  ? 0.97375 1.06615 0.99263 0.02149  0.02733  -0.01927 50  HIS A CE1 
737  N NE2 . HIS A 50  ? 1.00189 1.10972 1.02085 0.02815  0.03700  -0.01043 50  HIS A NE2 
745  N N   . LYS A 51  ? 0.60327 0.67769 0.63083 0.00523  0.01374  -0.00016 51  LYS A N   
746  C CA  . LYS A 51  ? 0.57813 0.63833 0.61381 -0.00136 0.00507  -0.00370 51  LYS A CA  
747  C C   . LYS A 51  ? 0.57438 0.63442 0.61834 -0.00069 0.00456  -0.00663 51  LYS A C   
748  O O   . LYS A 51  ? 0.64003 0.70997 0.69706 0.00289  0.01081  -0.00037 51  LYS A O   
749  C CB  . LYS A 51  ? 0.62326 0.67932 0.67662 -0.00552 0.00214  0.00479  51  LYS A CB  
750  C CG  . LYS A 51  ? 0.63747 0.68785 0.68493 -0.00732 0.00012  0.00554  51  LYS A CG  
751  C CD  . LYS A 51  ? 0.82143 0.86689 0.89086 -0.01116 -0.00276 0.01288  51  LYS A CD  
752  C CE  . LYS A 51  ? 0.89994 0.93612 0.96549 -0.01298 -0.00581 0.01136  51  LYS A CE  
753  N NZ  . LYS A 51  ? 0.97128 1.00592 1.01304 -0.01099 -0.00550 0.00399  51  LYS A NZ  
767  N N   . SER A 52  ? 0.67405 0.72345 0.71191 -0.00361 -0.00217 -0.01479 52  SER A N   
768  C CA  . SER A 52  ? 0.59658 0.64318 0.64436 -0.00366 -0.00479 -0.01653 52  SER A CA  
769  C C   . SER A 52  ? 0.55546 0.59048 0.60579 -0.00941 -0.01536 -0.01644 52  SER A C   
770  O O   . SER A 52  ? 0.58647 0.61288 0.62515 -0.01106 -0.01977 -0.02167 52  SER A O   
771  C CB  . SER A 52  ? 0.66787 0.71330 0.70637 -0.00050 -0.00262 -0.02558 52  SER A CB  
772  O OG  . SER A 52  ? 0.83414 0.87326 0.88204 -0.00143 -0.00691 -0.02658 52  SER A OG  
778  N N   . GLY A 53  ? 0.46459 0.50018 0.53073 -0.01213 -0.01950 -0.01035 53  GLY A N   
779  C CA  . GLY A 53  ? 0.40427 0.42991 0.47052 -0.01692 -0.03088 -0.01191 53  GLY A CA  
780  C C   . GLY A 53  ? 0.48187 0.49905 0.53090 -0.01905 -0.03350 -0.01639 53  GLY A C   
781  O O   . GLY A 53  ? 0.64257 0.66018 0.69565 -0.02006 -0.03194 -0.01412 53  GLY A O   
785  N N   . GLU A 54  ? 0.65625 0.66591 0.68805 -0.01928 -0.03674 -0.02168 54  GLU A N   
786  C CA  . GLU A 54  ? 0.57225 0.57483 0.58717 -0.02015 -0.03749 -0.02588 54  GLU A CA  
787  C C   . GLU A 54  ? 0.53117 0.53633 0.53460 -0.01801 -0.02982 -0.02806 54  GLU A C   
788  O O   . GLU A 54  ? 0.59283 0.59421 0.58512 -0.01823 -0.02890 -0.03046 54  GLU A O   
789  C CB  . GLU A 54  ? 0.53942 0.53325 0.54246 -0.02118 -0.04565 -0.02910 54  GLU A CB  
790  C CG  . GLU A 54  ? 0.70449 0.69469 0.71516 -0.02351 -0.05613 -0.03007 54  GLU A CG  
791  C CD  . GLU A 54  ? 0.73750 0.72289 0.74897 -0.02499 -0.05741 -0.03349 54  GLU A CD  
792  O OE1 . GLU A 54  ? 0.60944 0.59054 0.60534 -0.02356 -0.05327 -0.03687 54  GLU A OE1 
793  O OE2 . GLU A 54  ? 0.73478 0.72067 0.76523 -0.02751 -0.06244 -0.03241 54  GLU A OE2 
800  N N   . PHE A 55  ? 0.46918 0.48074 0.47615 -0.01569 -0.02484 -0.02821 55  PHE A N   
801  C CA  . PHE A 55  ? 0.44083 0.45608 0.43944 -0.01379 -0.01932 -0.03200 55  PHE A CA  
802  C C   . PHE A 55  ? 0.44794 0.47264 0.44805 -0.01145 -0.01410 -0.02943 55  PHE A C   
803  O O   . PHE A 55  ? 0.44052 0.47297 0.45014 -0.00910 -0.01064 -0.02560 55  PHE A O   
804  C CB  . PHE A 55  ? 0.52836 0.54520 0.53068 -0.01187 -0.01738 -0.03549 55  PHE A CB  
805  C CG  . PHE A 55  ? 0.46374 0.48304 0.45942 -0.01070 -0.01424 -0.04180 55  PHE A CG  
806  C CD1 . PHE A 55  ? 0.41392 0.44329 0.40787 -0.00710 -0.00985 -0.04488 55  PHE A CD1 
807  C CD2 . PHE A 55  ? 0.43164 0.44430 0.42358 -0.01292 -0.01595 -0.04427 55  PHE A CD2 
808  C CE1 . PHE A 55  ? 0.41509 0.44754 0.40358 -0.00612 -0.00924 -0.05226 55  PHE A CE1 
809  C CE2 . PHE A 55  ? 0.38802 0.40358 0.37843 -0.01262 -0.01433 -0.05050 55  PHE A CE2 
810  C CZ  . PHE A 55  ? 0.31963 0.34487 0.30821 -0.00941 -0.01200 -0.05547 55  PHE A CZ  
820  N N   . CYS A 56  ? 0.52621 0.55128 0.51811 -0.01149 -0.01298 -0.02993 56  CYS A N   
821  C CA  . CYS A 56  ? 0.52274 0.55740 0.51560 -0.00865 -0.00836 -0.02530 56  CYS A CA  
822  C C   . CYS A 56  ? 0.53198 0.57397 0.51447 -0.00599 -0.00607 -0.02965 56  CYS A C   
823  O O   . CYS A 56  ? 0.49186 0.52912 0.46841 -0.00786 -0.00840 -0.03421 56  CYS A O   
824  C CB  . CYS A 56  ? 0.55757 0.58737 0.55404 -0.01036 -0.00975 -0.02055 56  CYS A CB  
825  S SG  . CYS A 56  ? 0.68697 0.72949 0.69061 -0.00630 -0.00321 -0.01016 56  CYS A SG  
831  N N   . ARG A 57  ? 0.46780 0.52259 0.44862 -0.00122 -0.00160 -0.02773 57  ARG A N   
832  C CA  . ARG A 57  ? 0.42455 0.48857 0.39502 0.00218  -0.00114 -0.03405 57  ARG A CA  
833  C C   . ARG A 57  ? 0.43416 0.51067 0.40025 0.00661  0.00203  -0.02637 57  ARG A C   
834  O O   . ARG A 57  ? 0.45066 0.53576 0.41972 0.01060  0.00737  -0.01804 57  ARG A O   
835  C CB  . ARG A 57  ? 0.52506 0.59406 0.49421 0.00571  0.00081  -0.04114 57  ARG A CB  
836  C CG  . ARG A 57  ? 0.72859 0.80457 0.68807 0.00859  -0.00123 -0.05228 57  ARG A CG  
837  C CD  . ARG A 57  ? 0.63768 0.72105 0.59418 0.01464  0.00237  -0.05927 57  ARG A CD  
838  N NE  . ARG A 57  ? 0.94875 1.02135 0.91591 0.01248  0.00208  -0.06422 57  ARG A NE  
839  C CZ  . ARG A 57  ? 0.92535 0.99355 0.89452 0.01274  -0.00056 -0.07710 57  ARG A CZ  
840  N NH1 . ARG A 57  ? 0.91711 0.99068 0.87840 0.01455  -0.00423 -0.08848 57  ARG A NH1 
841  N NH2 . ARG A 57  ? 0.88184 0.94021 0.86325 0.01127  -0.00019 -0.07866 57  ARG A NH2 
855  N N   . LEU A 58  ? 0.49630 0.57495 0.45725 0.00638  -0.00070 -0.02737 58  LEU A N   
856  C CA  . LEU A 58  ? 0.47031 0.56149 0.42772 0.01112  0.00153  -0.01869 58  LEU A CA  
857  C C   . LEU A 58  ? 0.54354 0.64811 0.48844 0.01536  -0.00146 -0.02639 58  LEU A C   
858  O O   . LEU A 58  ? 0.46120 0.56294 0.40544 0.01238  -0.00702 -0.03473 58  LEU A O   
859  C CB  . LEU A 58  ? 0.44366 0.52793 0.40753 0.00846  0.00025  -0.01273 58  LEU A CB  
860  C CG  . LEU A 58  ? 0.40905 0.48077 0.38541 0.00513  0.00174  -0.00582 58  LEU A CG  
861  C CD1 . LEU A 58  ? 0.67419 0.73049 0.65156 -0.00050 -0.00193 -0.01441 58  LEU A CD1 
862  C CD2 . LEU A 58  ? 0.44543 0.51627 0.42750 0.00619  0.00234  0.00163  58  LEU A CD2 
874  N N   . ARG A 59  ? 0.63082 0.75065 0.56640 0.02259  0.00208  -0.02378 59  ARG A N   
875  C CA  . ARG A 59  ? 0.65046 0.78538 0.57120 0.02814  -0.00186 -0.03194 59  ARG A CA  
876  C C   . ARG A 59  ? 0.63937 0.78887 0.55499 0.03345  -0.00135 -0.01931 59  ARG A C   
877  O O   . ARG A 59  ? 0.61651 0.77301 0.53326 0.03802  0.00600  -0.00422 59  ARG A O   
878  C CB  . ARG A 59  ? 0.66567 0.80941 0.57577 0.03460  0.00201  -0.03841 59  ARG A CB  
879  C CG  . ARG A 59  ? 0.77212 0.93457 0.66292 0.04279  -0.00150 -0.04579 59  ARG A CG  
880  C CD  . ARG A 59  ? 0.98652 1.14445 0.87611 0.03928  -0.01177 -0.06632 59  ARG A CD  
881  N NE  . ARG A 59  ? 0.88426 1.02766 0.78247 0.03534  -0.01098 -0.07801 59  ARG A NE  
882  C CZ  . ARG A 59  ? 0.94934 1.08516 0.85292 0.03123  -0.01866 -0.09485 59  ARG A CZ  
883  N NH1 . ARG A 59  ? 0.89331 1.03469 0.79584 0.02970  -0.02834 -0.10302 59  ARG A NH1 
884  N NH2 . ARG A 59  ? 1.08775 1.21056 1.00088 0.02864  -0.01682 -0.10298 59  ARG A NH2 
898  N N   . PHE A 60  ? 0.63800 0.79260 0.55089 0.03296  -0.00894 -0.02402 60  PHE A N   
899  C CA  . PHE A 60  ? 0.62930 0.79761 0.53974 0.03797  -0.00959 -0.01125 60  PHE A CA  
900  C C   . PHE A 60  ? 0.62330 0.81434 0.51341 0.04747  -0.01254 -0.01374 60  PHE A C   
901  O O   . PHE A 60  ? 0.56614 0.76085 0.44537 0.04856  -0.01798 -0.03088 60  PHE A O   
902  C CB  . PHE A 60  ? 0.70108 0.86423 0.62210 0.03289  -0.01626 -0.01338 60  PHE A CB  
903  C CG  . PHE A 60  ? 0.54672 0.69060 0.48432 0.02625  -0.01225 -0.00802 60  PHE A CG  
904  C CD1 . PHE A 60  ? 0.50453 0.63138 0.44788 0.01918  -0.01249 -0.01804 60  PHE A CD1 
905  C CD2 . PHE A 60  ? 0.45977 0.60262 0.40689 0.02787  -0.00825 0.00699  60  PHE A CD2 
906  C CE1 . PHE A 60  ? 0.46303 0.57347 0.41769 0.01433  -0.00939 -0.01408 60  PHE A CE1 
907  C CE2 . PHE A 60  ? 0.50205 0.62686 0.46268 0.02263  -0.00521 0.00925  60  PHE A CE2 
908  C CZ  . PHE A 60  ? 0.43858 0.54776 0.40114 0.01611  -0.00604 -0.00175 60  PHE A CZ  
918  N N   . PRO A 61  ? 0.58617 0.79307 0.47078 0.05508  -0.00940 0.00309  61  PRO A N   
919  C CA  . PRO A 61  ? 0.58052 0.81156 0.44140 0.06607  -0.01150 0.00238  61  PRO A CA  
920  C C   . PRO A 61  ? 0.63718 0.87835 0.48868 0.06664  -0.02578 -0.01344 61  PRO A C   
921  O O   . PRO A 61  ? 0.63791 0.89572 0.46738 0.07448  -0.03045 -0.02340 61  PRO A O   
922  C CB  . PRO A 61  ? 0.68169 0.92576 0.54393 0.07326  -0.00443 0.02832  61  PRO A CB  
923  C CG  . PRO A 61  ? 0.70517 0.93261 0.59301 0.06527  -0.00389 0.03755  61  PRO A CG  
924  C CD  . PRO A 61  ? 0.59328 0.79665 0.49351 0.05467  -0.00362 0.02375  61  PRO A CD  
932  N N   . LYS A 62  ? 0.80896 1.04110 0.67741 0.05888  -0.03292 -0.01657 62  LYS A N   
933  C CA  . LYS A 62  ? 0.75752 1.00096 0.62485 0.05880  -0.04676 -0.02671 62  LYS A CA  
934  C C   . LYS A 62  ? 0.72067 0.94446 0.61091 0.04706  -0.05011 -0.03614 62  LYS A C   
935  O O   . LYS A 62  ? 0.69415 0.90166 0.59970 0.04181  -0.04219 -0.02643 62  LYS A O   
936  C CB  . LYS A 62  ? 0.89708 1.15744 0.76510 0.06487  -0.04924 -0.00880 62  LYS A CB  
937  C CG  . LYS A 62  ? 1.00154 1.27962 0.85109 0.07653  -0.04225 0.00797  62  LYS A CG  
938  C CD  . LYS A 62  ? 1.13320 1.42223 0.99139 0.08128  -0.04142 0.03098  62  LYS A CD  
939  C CE  . LYS A 62  ? 1.20061 1.50495 1.05994 0.08253  -0.05671 0.02563  62  LYS A CE  
940  N NZ  . LYS A 62  ? 1.38515 1.69156 1.26441 0.08361  -0.05511 0.04651  62  LYS A NZ  
954  N N   . PRO A 63  ? 0.61324 0.83826 0.50731 0.04301  -0.06147 -0.05453 63  PRO A N   
955  C CA  . PRO A 63  ? 0.61257 0.81825 0.52900 0.03212  -0.06202 -0.06216 63  PRO A CA  
956  C C   . PRO A 63  ? 0.63848 0.84018 0.57345 0.02879  -0.05961 -0.04840 63  PRO A C   
957  O O   . PRO A 63  ? 0.54213 0.75911 0.48021 0.03229  -0.06572 -0.04214 63  PRO A O   
958  C CB  . PRO A 63  ? 0.51193 0.72397 0.43130 0.02964  -0.07572 -0.08296 63  PRO A CB  
959  C CG  . PRO A 63  ? 0.49671 0.73345 0.39789 0.03882  -0.08495 -0.08431 63  PRO A CG  
960  C CD  . PRO A 63  ? 0.52241 0.76576 0.40176 0.04808  -0.07436 -0.07008 63  PRO A CD  
968  N N   . ILE A 64  ? 0.66098 0.84252 0.60785 0.02283  -0.05063 -0.04378 64  ILE A N   
969  C CA  . ILE A 64  ? 0.57634 0.75242 0.53942 0.02072  -0.04676 -0.03224 64  ILE A CA  
970  C C   . ILE A 64  ? 0.53822 0.71247 0.51992 0.01448  -0.05230 -0.04013 64  ILE A C   
971  O O   . ILE A 64  ? 0.72419 0.90566 0.71904 0.01527  -0.05411 -0.03322 64  ILE A O   
972  C CB  . ILE A 64  ? 0.50029 0.65672 0.46590 0.01828  -0.03532 -0.02456 64  ILE A CB  
973  C CG1 . ILE A 64  ? 0.52825 0.68728 0.48054 0.02367  -0.02980 -0.01633 64  ILE A CG1 
974  C CG2 . ILE A 64  ? 0.51257 0.66314 0.49282 0.01768  -0.03097 -0.01447 64  ILE A CG2 
975  C CD1 . ILE A 64  ? 0.55829 0.73443 0.50642 0.03166  -0.03008 -0.00249 64  ILE A CD1 
987  N N   . ARG A 65  ? 0.51231 0.67741 0.49828 0.00851  -0.05441 -0.05337 65  ARG A N   
988  C CA  . ARG A 65  ? 0.61532 0.77694 0.62285 0.00181  -0.05765 -0.05916 65  ARG A CA  
989  C C   . ARG A 65  ? 0.68506 0.85783 0.69639 0.00022  -0.07074 -0.07496 65  ARG A C   
990  O O   . ARG A 65  ? 0.55818 0.72196 0.57092 -0.00368 -0.07231 -0.08707 65  ARG A O   
991  C CB  . ARG A 65  ? 0.47771 0.61822 0.49103 -0.00396 -0.04870 -0.05953 65  ARG A CB  
992  C CG  . ARG A 65  ? 0.49689 0.62577 0.50825 -0.00282 -0.03757 -0.04691 65  ARG A CG  
993  C CD  . ARG A 65  ? 0.51721 0.64802 0.54624 -0.00362 -0.03468 -0.03997 65  ARG A CD  
994  N NE  . ARG A 65  ? 0.40319 0.53202 0.45044 -0.00956 -0.03591 -0.04529 65  ARG A NE  
995  C CZ  . ARG A 65  ? 0.43235 0.54706 0.48439 -0.01306 -0.02784 -0.04352 65  ARG A CZ  
996  N NH1 . ARG A 65  ? 0.45124 0.55237 0.49003 -0.01132 -0.01932 -0.03854 65  ARG A NH1 
997  N NH2 . ARG A 65  ? 0.46899 0.58379 0.54029 -0.01825 -0.02882 -0.04658 65  ARG A NH2 
1011 N N   . THR A 66  ? 0.73245 0.92495 0.74674 0.00358  -0.08095 -0.07516 66  THR A N   
1012 C CA  . THR A 66  ? 0.63381 0.83877 0.65491 0.00193  -0.09611 -0.09140 66  THR A CA  
1013 C C   . THR A 66  ? 0.56457 0.75800 0.61297 -0.00773 -0.09757 -0.10054 66  THR A C   
1014 O O   . THR A 66  ? 0.55887 0.75239 0.61233 -0.01072 -0.10708 -0.11767 66  THR A O   
1015 C CB  . THR A 66  ? 0.72320 0.95088 0.75103 0.00575  -0.10681 -0.08687 66  THR A CB  
1016 O OG1 . THR A 66  ? 0.89405 1.11932 0.94661 0.00236  -0.10106 -0.07425 66  THR A OG1 
1017 C CG2 . THR A 66  ? 0.80130 1.04268 0.80266 0.01630  -0.10595 -0.07617 66  THR A CG2 
1025 N N   . ASP A 67  ? 0.71516 0.89825 0.78157 -0.01208 -0.08744 -0.08896 67  ASP A N   
1026 C CA  . ASP A 67  ? 0.59361 0.77052 0.69095 -0.02049 -0.08813 -0.09272 67  ASP A CA  
1027 C C   . ASP A 67  ? 0.58223 0.73997 0.68088 -0.02536 -0.08294 -0.09977 67  ASP A C   
1028 O O   . ASP A 67  ? 0.60025 0.75446 0.72460 -0.03211 -0.08714 -0.10710 67  ASP A O   
1029 C CB  . ASP A 67  ? 0.64350 0.81840 0.75774 -0.02158 -0.07752 -0.07651 67  ASP A CB  
1030 C CG  . ASP A 67  ? 0.51240 0.67114 0.60869 -0.01886 -0.06194 -0.06530 67  ASP A CG  
1031 O OD1 . ASP A 67  ? 0.53475 0.69206 0.60580 -0.01343 -0.05998 -0.06325 67  ASP A OD1 
1032 O OD2 . ASP A 67  ? 0.55020 0.69816 0.65839 -0.02196 -0.05170 -0.05837 67  ASP A OD2 
1037 N N   . VAL A 68  ? 0.67539 0.82117 0.75072 -0.02226 -0.07424 -0.09687 68  VAL A N   
1038 C CA  . VAL A 68  ? 0.63518 0.76302 0.71282 -0.02621 -0.06869 -0.10103 68  VAL A CA  
1039 C C   . VAL A 68  ? 0.65245 0.78097 0.72477 -0.02569 -0.07820 -0.11932 68  VAL A C   
1040 O O   . VAL A 68  ? 0.64120 0.78210 0.69481 -0.01983 -0.08544 -0.12678 68  VAL A O   
1041 C CB  . VAL A 68  ? 0.59637 0.71141 0.65375 -0.02319 -0.05604 -0.09012 68  VAL A CB  
1042 C CG1 . VAL A 68  ? 0.71541 0.82550 0.77992 -0.02414 -0.04601 -0.07521 68  VAL A CG1 
1043 C CG2 . VAL A 68  ? 0.66386 0.78668 0.69486 -0.01581 -0.05663 -0.08883 68  VAL A CG2 
1053 N N   . THR A 69  ? 0.61688 0.73220 0.70601 -0.03109 -0.07769 -0.12632 69  THR A N   
1054 C CA  . THR A 69  ? 0.56349 0.67393 0.64882 -0.03025 -0.08366 -0.14375 69  THR A CA  
1055 C C   . THR A 69  ? 0.59472 0.69253 0.65982 -0.02663 -0.07299 -0.13874 69  THR A C   
1056 O O   . THR A 69  ? 0.61218 0.70085 0.67556 -0.02773 -0.06234 -0.12359 69  THR A O   
1057 C CB  . THR A 69  ? 0.65839 0.76005 0.77848 -0.03815 -0.08874 -0.15317 69  THR A CB  
1058 O OG1 . THR A 69  ? 0.83571 0.91927 0.96471 -0.04133 -0.07738 -0.14357 69  THR A OG1 
1059 C CG2 . THR A 69  ? 0.69788 0.80918 0.84724 -0.04390 -0.09424 -0.14919 69  THR A CG2 
1067 N N   . GLY A 70  ? 0.57599 0.67453 0.62542 -0.02162 -0.07615 -0.15195 70  GLY A N   
1068 C CA  . GLY A 70  ? 0.54062 0.62833 0.57561 -0.01825 -0.06662 -0.14792 70  GLY A CA  
1069 C C   . GLY A 70  ? 0.44213 0.51163 0.49844 -0.02384 -0.06222 -0.14694 70  GLY A C   
1070 O O   . GLY A 70  ? 0.52507 0.58979 0.60675 -0.02913 -0.06790 -0.15558 70  GLY A O   
1074 N N   . MET A 71  ? 0.54967 0.60928 0.59786 -0.02274 -0.05235 -0.13507 71  MET A N   
1075 C CA  . MET A 71  ? 0.55486 0.59836 0.62079 -0.02689 -0.04757 -0.13055 71  MET A CA  
1076 C C   . MET A 71  ? 0.53310 0.56964 0.59006 -0.02228 -0.04393 -0.13471 71  MET A C   
1077 O O   . MET A 71  ? 0.52823 0.57205 0.56342 -0.01610 -0.04205 -0.13584 71  MET A O   
1078 C CB  . MET A 71  ? 0.53475 0.57264 0.60149 -0.02975 -0.03952 -0.11117 71  MET A CB  
1079 C CG  . MET A 71  ? 0.60211 0.64235 0.68795 -0.03513 -0.04003 -0.10495 71  MET A CG  
1080 S SD  . MET A 71  ? 0.62528 0.65777 0.70817 -0.03627 -0.02885 -0.08378 71  MET A SD  
1081 C CE  . MET A 71  ? 0.69245 0.70944 0.78176 -0.03671 -0.02494 -0.08050 71  MET A CE  
1091 N N   . ILE A 72  ? 0.67550 0.69853 0.75197 -0.02500 -0.04231 -0.13553 72  ILE A N   
1092 C CA  . ILE A 72  ? 0.56840 0.58402 0.64181 -0.02064 -0.03853 -0.13852 72  ILE A CA  
1093 C C   . ILE A 72  ? 0.56041 0.57333 0.62090 -0.01934 -0.03096 -0.12098 72  ILE A C   
1094 O O   . ILE A 72  ? 0.60331 0.61099 0.66901 -0.02335 -0.02803 -0.10709 72  ILE A O   
1095 C CB  . ILE A 72  ? 0.63260 0.63430 0.73495 -0.02376 -0.03971 -0.14421 72  ILE A CB  
1096 C CG1 . ILE A 72  ? 0.67999 0.68376 0.79717 -0.02513 -0.04903 -0.16499 72  ILE A CG1 
1097 C CG2 . ILE A 72  ? 0.72051 0.71451 0.82204 -0.01862 -0.03503 -0.14535 72  ILE A CG2 
1098 C CD1 . ILE A 72  ? 0.82656 0.82049 0.97980 -0.03297 -0.05192 -0.16401 72  ILE A CD1 
1110 N N   . LEU A 73  ? 0.52805 0.54549 0.57196 -0.01337 -0.02792 -0.12179 73  LEU A N   
1111 C CA  . LEU A 73  ? 0.51448 0.52998 0.54895 -0.01208 -0.02240 -0.10740 73  LEU A CA  
1112 C C   . LEU A 73  ? 0.55354 0.56285 0.59538 -0.00842 -0.01953 -0.10961 73  LEU A C   
1113 O O   . LEU A 73  ? 0.47411 0.48831 0.51239 -0.00282 -0.01887 -0.12125 73  LEU A O   
1114 C CB  . LEU A 73  ? 0.51359 0.54116 0.52715 -0.00846 -0.02064 -0.10340 73  LEU A CB  
1115 C CG  . LEU A 73  ? 0.46308 0.48935 0.46956 -0.00762 -0.01630 -0.08990 73  LEU A CG  
1116 C CD1 . LEU A 73  ? 0.48625 0.50329 0.49719 -0.01264 -0.01642 -0.07883 73  LEU A CD1 
1117 C CD2 . LEU A 73  ? 0.51523 0.55352 0.50612 -0.00457 -0.01483 -0.08627 73  LEU A CD2 
1129 N N   . GLU A 74  ? 0.53585 0.53558 0.58712 -0.01063 -0.01763 -0.09812 74  GLU A N   
1130 C CA  . GLU A 74  ? 0.54021 0.53388 0.60235 -0.00730 -0.01528 -0.09762 74  GLU A CA  
1131 C C   . GLU A 74  ? 0.57734 0.56985 0.63477 -0.00751 -0.01365 -0.08194 74  GLU A C   
1132 O O   . GLU A 74  ? 0.55078 0.54349 0.59912 -0.01091 -0.01467 -0.07215 74  GLU A O   
1133 C CB  . GLU A 74  ? 0.54967 0.53133 0.63630 -0.00955 -0.01667 -0.10104 74  GLU A CB  
1134 C CG  . GLU A 74  ? 0.54645 0.52806 0.64196 -0.01087 -0.02058 -0.11787 74  GLU A CG  
1135 C CD  . GLU A 74  ? 0.63524 0.60406 0.75980 -0.01192 -0.02174 -0.12439 74  GLU A CD  
1136 O OE1 . GLU A 74  ? 0.76415 0.72361 0.90486 -0.01486 -0.02000 -0.11060 74  GLU A OE1 
1137 O OE2 . GLU A 74  ? 0.61915 0.58738 0.75057 -0.00929 -0.02457 -0.14351 74  GLU A OE2 
1144 N N   . GLU A 75  ? 0.51056 0.50255 0.57472 -0.00328 -0.01148 -0.08082 75  GLU A N   
1145 C CA  . GLU A 75  ? 0.51251 0.50426 0.57630 -0.00312 -0.01171 -0.06746 75  GLU A CA  
1146 C C   . GLU A 75  ? 0.47604 0.45769 0.55112 -0.00593 -0.01420 -0.05752 75  GLU A C   
1147 O O   . GLU A 75  ? 0.56762 0.54368 0.66001 -0.00360 -0.01371 -0.05593 75  GLU A O   
1148 C CB  . GLU A 75  ? 0.58631 0.58281 0.65738 0.00281  -0.00824 -0.06951 75  GLU A CB  
1149 C CG  . GLU A 75  ? 0.76480 0.76238 0.84065 0.00302  -0.00983 -0.05672 75  GLU A CG  
1150 C CD  . GLU A 75  ? 1.07931 1.08237 1.16768 0.00927  -0.00534 -0.05836 75  GLU A CD  
1151 O OE1 . GLU A 75  ? 0.98275 0.99145 1.06854 0.01409  0.00023  -0.06928 75  GLU A OE1 
1152 O OE2 . GLU A 75  ? 1.22622 1.22896 1.32692 0.01003  -0.00737 -0.04880 75  GLU A OE2 
1159 N N   . GLY A 76  ? 0.56791 0.54785 0.63325 -0.01008 -0.01617 -0.04987 76  GLY A N   
1160 C CA  . GLY A 76  ? 0.52448 0.49698 0.59664 -0.01179 -0.01746 -0.03827 76  GLY A CA  
1161 C C   . GLY A 76  ? 0.53235 0.49719 0.62450 -0.01310 -0.01569 -0.04063 76  GLY A C   
1162 O O   . GLY A 76  ? 0.53705 0.50183 0.63724 -0.01310 -0.01480 -0.05413 76  GLY A O   
1166 N N   . ALA A 77  ? 0.53105 0.48978 0.63197 -0.01399 -0.01547 -0.02741 77  ALA A N   
1167 C CA  . ALA A 77  ? 0.53993 0.49037 0.66573 -0.01555 -0.01334 -0.02622 77  ALA A CA  
1168 C C   . ALA A 77  ? 0.54409 0.48831 0.68824 -0.01204 -0.01348 -0.01663 77  ALA A C   
1169 O O   . ALA A 77  ? 0.57259 0.52041 0.70717 -0.00892 -0.01595 -0.00913 77  ALA A O   
1170 C CB  . ALA A 77  ? 0.64668 0.59644 0.77076 -0.01923 -0.01096 -0.01543 77  ALA A CB  
1176 N N   . PRO A 78  ? 0.57808 0.51309 0.75116 -0.01237 -0.01153 -0.01660 78  PRO A N   
1177 C CA  . PRO A 78  ? 0.60653 0.53551 0.79941 -0.00840 -0.01137 -0.00486 78  PRO A CA  
1178 C C   . PRO A 78  ? 0.56432 0.49609 0.74602 -0.00742 -0.01212 0.01791  78  PRO A C   
1179 O O   . PRO A 78  ? 0.59848 0.53220 0.76942 -0.01021 -0.01014 0.02650  78  PRO A O   
1180 C CB  . PRO A 78  ? 0.53783 0.45527 0.76582 -0.01007 -0.00876 -0.00883 78  PRO A CB  
1181 C CG  . PRO A 78  ? 0.48542 0.40393 0.71129 -0.01325 -0.00959 -0.03158 78  PRO A CG  
1182 C CD  . PRO A 78  ? 0.65926 0.58908 0.85125 -0.01578 -0.01055 -0.03049 78  PRO A CD  
1190 N N   . GLU A 79  ? 0.59843 0.53178 0.78159 -0.00268 -0.01518 0.02733  79  GLU A N   
1191 C CA  . GLU A 79  ? 0.58736 0.52424 0.75997 -0.00024 -0.01759 0.04878  79  GLU A CA  
1192 C C   . GLU A 79  ? 0.54855 0.48009 0.73484 -0.00135 -0.01239 0.06451  79  GLU A C   
1193 O O   . GLU A 79  ? 0.62661 0.54890 0.84591 -0.00150 -0.00881 0.06616  79  GLU A O   
1194 C CB  . GLU A 79  ? 0.54936 0.48715 0.73467 0.00533  -0.02189 0.05665  79  GLU A CB  
1195 C CG  . GLU A 79  ? 0.60751 0.55333 0.78020 0.00684  -0.02705 0.04623  79  GLU A CG  
1196 C CD  . GLU A 79  ? 0.54513 0.48831 0.73477 0.00774  -0.02352 0.02790  79  GLU A CD  
1197 O OE1 . GLU A 79  ? 0.54687 0.48099 0.75714 0.00713  -0.01843 0.02017  79  GLU A OE1 
1198 O OE2 . GLU A 79  ? 0.48303 0.43374 0.66567 0.00942  -0.02585 0.02110  79  GLU A OE2 
1205 N N   . GLY A 80  ? 0.53629 0.47367 0.69872 -0.00166 -0.01140 0.07635  80  GLY A N   
1206 C CA  . GLY A 80  ? 0.48970 0.42472 0.66274 -0.00204 -0.00467 0.09398  80  GLY A CA  
1207 C C   . GLY A 80  ? 0.50988 0.44398 0.68551 -0.00778 0.00133  0.08642  80  GLY A C   
1208 O O   . GLY A 80  ? 0.57826 0.51234 0.76250 -0.00830 0.00818  0.10225  80  GLY A O   
1212 N N   . THR A 81  ? 0.55954 0.49425 0.72902 -0.01166 -0.00082 0.06416  81  THR A N   
1213 C CA  . THR A 81  ? 0.52643 0.46201 0.69889 -0.01699 0.00330  0.05637  81  THR A CA  
1214 C C   . THR A 81  ? 0.50429 0.44869 0.64575 -0.01617 0.00625  0.06502  81  THR A C   
1215 O O   . THR A 81  ? 0.55214 0.50221 0.66249 -0.01330 0.00207  0.06274  81  THR A O   
1216 C CB  . THR A 81  ? 0.51259 0.44833 0.68383 -0.02001 -0.00074 0.03106  81  THR A CB  
1217 O OG1 . THR A 81  ? 0.45384 0.38071 0.65675 -0.02066 -0.00189 0.02099  81  THR A OG1 
1218 C CG2 . THR A 81  ? 0.49394 0.43424 0.66049 -0.02473 0.00162  0.02384  81  THR A CG2 
1226 N N   . VAL A 82  ? 0.47778 0.42341 0.62959 -0.01853 0.01365  0.07423  82  VAL A N   
1227 C CA  . VAL A 82  ? 0.43940 0.39360 0.56360 -0.01693 0.01832  0.08133  82  VAL A CA  
1228 C C   . VAL A 82  ? 0.53194 0.48950 0.64957 -0.02132 0.01689  0.06218  82  VAL A C   
1229 O O   . VAL A 82  ? 0.47635 0.43404 0.61618 -0.02601 0.02048  0.05905  82  VAL A O   
1230 C CB  . VAL A 82  ? 0.43340 0.38951 0.57203 -0.01599 0.02881  0.10367  82  VAL A CB  
1231 C CG1 . VAL A 82  ? 0.59809 0.56369 0.70963 -0.01376 0.03532  0.10842  82  VAL A CG1 
1232 C CG2 . VAL A 82  ? 0.47227 0.42717 0.61162 -0.00998 0.02992  0.12523  82  VAL A CG2 
1242 N N   . ALA A 83  ? 0.66265 0.62356 0.75186 -0.01981 0.01114  0.05010  83  ALA A N   
1243 C CA  . ALA A 83  ? 0.53485 0.50006 0.61576 -0.02283 0.00997  0.03458  83  ALA A CA  
1244 C C   . ALA A 83  ? 0.53549 0.50726 0.59790 -0.02111 0.01636  0.04195  83  ALA A C   
1245 O O   . ALA A 83  ? 0.52007 0.49358 0.57025 -0.01674 0.02129  0.05747  83  ALA A O   
1246 C CB  . ALA A 83  ? 0.57609 0.54224 0.63829 -0.02172 0.00237  0.02044  83  ALA A CB  
1252 N N   . THR A 84  ? 0.67974 0.65602 0.73950 -0.02365 0.01653  0.03084  84  THR A N   
1253 C CA  . THR A 84  ? 0.55818 0.54080 0.60049 -0.02135 0.02256  0.03488  84  THR A CA  
1254 C C   . THR A 84  ? 0.52597 0.51031 0.54292 -0.01982 0.01709  0.02199  84  THR A C   
1255 O O   . THR A 84  ? 0.51824 0.50269 0.54063 -0.02270 0.01120  0.00879  84  THR A O   
1256 C CB  . THR A 84  ? 0.50805 0.49552 0.57436 -0.02542 0.02801  0.03514  84  THR A CB  
1257 O OG1 . THR A 84  ? 0.60295 0.58777 0.69990 -0.02794 0.03241  0.04673  84  THR A OG1 
1258 C CG2 . THR A 84  ? 0.53522 0.52983 0.58617 -0.02179 0.03645  0.04178  84  THR A CG2 
1266 N N   . LEU A 85  ? 0.56520 0.55086 0.55483 -0.01475 0.01901  0.02592  85  LEU A N   
1267 C CA  . LEU A 85  ? 0.55791 0.54403 0.52577 -0.01308 0.01441  0.01493  85  LEU A CA  
1268 C C   . LEU A 85  ? 0.60631 0.59759 0.57141 -0.01207 0.02127  0.01378  85  LEU A C   
1269 O O   . LEU A 85  ? 0.56328 0.55657 0.51491 -0.00730 0.02848  0.02141  85  LEU A O   
1270 C CB  . LEU A 85  ? 0.54509 0.52846 0.48712 -0.00811 0.01049  0.01746  85  LEU A CB  
1271 C CG  . LEU A 85  ? 0.52416 0.50610 0.44711 -0.00670 0.00431  0.00611  85  LEU A CG  
1272 C CD1 . LEU A 85  ? 0.60270 0.58431 0.53744 -0.01103 -0.00162 -0.00460 85  LEU A CD1 
1273 C CD2 . LEU A 85  ? 0.58540 0.56464 0.48872 -0.00271 -0.00232 0.00849  85  LEU A CD2 
1285 N N   . LEU A 86  ? 0.57027 0.56477 0.54813 -0.01574 0.01931  0.00468  86  LEU A N   
1286 C CA  . LEU A 86  ? 0.52233 0.52306 0.50332 -0.01505 0.02511  0.00401  86  LEU A CA  
1287 C C   . LEU A 86  ? 0.50436 0.50374 0.46154 -0.01053 0.02462  -0.00147 86  LEU A C   
1288 O O   . LEU A 86  ? 0.49576 0.49566 0.45193 -0.01160 0.01954  -0.01041 86  LEU A O   
1289 C CB  . LEU A 86  ? 0.53729 0.54309 0.54010 -0.02009 0.02119  -0.00372 86  LEU A CB  
1290 C CG  . LEU A 86  ? 0.52941 0.53551 0.55961 -0.02511 0.01991  -0.00227 86  LEU A CG  
1291 C CD1 . LEU A 86  ? 0.60527 0.61837 0.65237 -0.02889 0.01480  -0.01244 86  LEU A CD1 
1292 C CD2 . LEU A 86  ? 0.70892 0.71624 0.75282 -0.02495 0.02908  0.01177  86  LEU A CD2 
1304 N N   . ILE A 87  ? 0.60400 0.60166 0.54203 -0.00486 0.03001  0.00392  87  ILE A N   
1305 C CA  . ILE A 87  ? 0.61509 0.60985 0.53157 -0.00005 0.02935  -0.00310 87  ILE A CA  
1306 C C   . ILE A 87  ? 0.55538 0.55575 0.47667 0.00275  0.03829  -0.00257 87  ILE A C   
1307 O O   . ILE A 87  ? 0.61514 0.62053 0.53963 0.00567  0.04853  0.00671  87  ILE A O   
1308 C CB  . ILE A 87  ? 0.56303 0.55319 0.45324 0.00579  0.02900  -0.00070 87  ILE A CB  
1309 C CG1 . ILE A 87  ? 0.59497 0.57962 0.48061 0.00321  0.01713  -0.00475 87  ILE A CG1 
1310 C CG2 . ILE A 87  ? 0.63635 0.62419 0.50651 0.01213  0.03170  -0.00789 87  ILE A CG2 
1311 C CD1 . ILE A 87  ? 0.87029 0.85272 0.73475 0.00805  0.01454  0.00035  87  ILE A CD1 
1323 N N   . LYS A 88  ? 0.50889 0.50935 0.43321 0.00215  0.03501  -0.01103 88  LYS A N   
1324 C CA  . LYS A 88  ? 0.50644 0.51069 0.43227 0.00641  0.04238  -0.01194 88  LYS A CA  
1325 C C   . LYS A 88  ? 0.55415 0.55027 0.45585 0.01290  0.04240  -0.01901 88  LYS A C   
1326 O O   . LYS A 88  ? 0.59382 0.58243 0.48629 0.01164  0.03312  -0.02643 88  LYS A O   
1327 C CB  . LYS A 88  ? 0.57521 0.58468 0.51942 0.00286  0.03829  -0.01609 88  LYS A CB  
1328 C CG  . LYS A 88  ? 0.62360 0.64124 0.58043 0.00596  0.04639  -0.01316 88  LYS A CG  
1329 C CD  . LYS A 88  ? 0.63389 0.65942 0.61013 0.00221  0.04065  -0.01533 88  LYS A CD  
1330 C CE  . LYS A 88  ? 0.60827 0.64124 0.60378 -0.00420 0.03717  -0.01242 88  LYS A CE  
1331 N NZ  . LYS A 88  ? 0.61883 0.66151 0.63077 -0.00691 0.03060  -0.01545 88  LYS A NZ  
1345 N N   . ARG A 89  ? 0.53768 0.53556 0.43130 0.02003  0.05282  -0.01743 89  ARG A N   
1346 C CA  . ARG A 89  ? 0.55254 0.54217 0.42236 0.02740  0.05331  -0.02634 89  ARG A CA  
1347 C C   . ARG A 89  ? 0.57501 0.56353 0.45342 0.03044  0.05612  -0.03286 89  ARG A C   
1348 O O   . ARG A 89  ? 0.57658 0.57388 0.47596 0.02945  0.06187  -0.02730 89  ARG A O   
1349 C CB  . ARG A 89  ? 0.61105 0.60301 0.46056 0.03568  0.06398  -0.02090 89  ARG A CB  
1350 C CG  . ARG A 89  ? 0.69099 0.68056 0.52271 0.03534  0.05849  -0.01719 89  ARG A CG  
1351 C CD  . ARG A 89  ? 0.73403 0.71278 0.54481 0.03660  0.04586  -0.03069 89  ARG A CD  
1352 N NE  . ARG A 89  ? 0.68319 0.66068 0.48538 0.03376  0.03677  -0.02698 89  ARG A NE  
1353 C CZ  . ARG A 89  ? 0.88461 0.86536 0.66661 0.03938  0.04008  -0.01925 89  ARG A CZ  
1354 N NH1 . ARG A 89  ? 0.91797 0.90414 0.68545 0.04823  0.05351  -0.01374 89  ARG A NH1 
1355 N NH2 . ARG A 89  ? 0.92991 0.90956 0.70659 0.03680  0.03028  -0.01580 89  ARG A NH2 
1369 N N   . PRO A 90  ? 0.59836 0.57625 0.46378 0.03404  0.05130  -0.04459 90  PRO A N   
1370 C CA  . PRO A 90  ? 0.54501 0.52061 0.42236 0.03705  0.05385  -0.04993 90  PRO A CA  
1371 C C   . PRO A 90  ? 0.56578 0.54865 0.44731 0.04447  0.06855  -0.04543 90  PRO A C   
1372 O O   . PRO A 90  ? 0.53841 0.52476 0.43926 0.04556  0.07184  -0.04445 90  PRO A O   
1373 C CB  . PRO A 90  ? 0.56650 0.52755 0.42760 0.04050  0.04674  -0.06413 90  PRO A CB  
1374 C CG  . PRO A 90  ? 0.75181 0.70929 0.59690 0.03669  0.03687  -0.06566 90  PRO A CG  
1375 C CD  . PRO A 90  ? 0.78034 0.74804 0.62118 0.03622  0.04340  -0.05353 90  PRO A CD  
1383 N N   . THR A 91  ? 0.70150 0.68817 0.56674 0.05016  0.07809  -0.04106 91  THR A N   
1384 C CA  . THR A 91  ? 0.61509 0.61090 0.48651 0.05765  0.09411  -0.03456 91  THR A CA  
1385 C C   . THR A 91  ? 0.58659 0.59680 0.48959 0.05145  0.09782  -0.02103 91  THR A C   
1386 O O   . THR A 91  ? 0.61639 0.63576 0.53476 0.05611  0.10935  -0.01530 91  THR A O   
1387 C CB  . THR A 91  ? 0.63091 0.62885 0.47573 0.06611  0.10455  -0.03117 91  THR A CB  
1388 O OG1 . THR A 91  ? 0.61457 0.61899 0.46099 0.06018  0.10313  -0.01884 91  THR A OG1 
1389 C CG2 . THR A 91  ? 0.67382 0.65831 0.48440 0.07296  0.09890  -0.04681 91  THR A CG2 
1397 N N   . GLY A 92  ? 0.50144 0.51407 0.41579 0.04136  0.08783  -0.01680 92  GLY A N   
1398 C CA  . GLY A 92  ? 0.49485 0.52029 0.43816 0.03485  0.08881  -0.00634 92  GLY A CA  
1399 C C   . GLY A 92  ? 0.54684 0.57686 0.49139 0.03156  0.09194  0.00393  92  GLY A C   
1400 O O   . GLY A 92  ? 0.54114 0.57856 0.51002 0.02384  0.08828  0.00990  92  GLY A O   
1404 N N   . GLU A 93  ? 0.63603 0.66190 0.55535 0.03764  0.09817  0.00603  93  GLU A N   
1405 C CA  . GLU A 93  ? 0.61050 0.64141 0.53224 0.03589  0.10315  0.01899  93  GLU A CA  
1406 C C   . GLU A 93  ? 0.60205 0.62865 0.53119 0.02604  0.08945  0.01801  93  GLU A C   
1407 O O   . GLU A 93  ? 0.62229 0.64027 0.54154 0.02311  0.07720  0.00707  93  GLU A O   
1408 C CB  . GLU A 93  ? 0.69136 0.71929 0.57951 0.04569  0.11122  0.02157  93  GLU A CB  
1409 C CG  . GLU A 93  ? 0.71472 0.75005 0.60690 0.04592  0.11987  0.03935  93  GLU A CG  
1410 C CD  . GLU A 93  ? 0.87581 0.91264 0.73428 0.05831  0.13139  0.04443  93  GLU A CD  
1411 O OE1 . GLU A 93  ? 0.96639 1.00058 0.80291 0.06761  0.13605  0.03417  93  GLU A OE1 
1412 O OE2 . GLU A 93  ? 0.99340 1.03412 0.84703 0.05941  0.13573  0.05866  93  GLU A OE2 
1419 N N   . LEU A 94  ? 0.68221 0.71514 0.63247 0.02101  0.09220  0.02978  94  LEU A N   
1420 C CA  . LEU A 94  ? 0.64659 0.67599 0.60854 0.01224  0.08103  0.02941  94  LEU A CA  
1421 C C   . LEU A 94  ? 0.63587 0.66192 0.58370 0.01444  0.08361  0.03903  94  LEU A C   
1422 O O   . LEU A 94  ? 0.67173 0.70430 0.62556 0.01779  0.09584  0.05359  94  LEU A O   
1423 C CB  . LEU A 94  ? 0.62935 0.66735 0.62999 0.00457  0.08055  0.03419  94  LEU A CB  
1424 C CG  . LEU A 94  ? 0.61937 0.66555 0.63893 0.00343  0.08009  0.02927  94  LEU A CG  
1425 C CD1 . LEU A 94  ? 0.63752 0.69226 0.69531 -0.00481 0.07669  0.03286  94  LEU A CD1 
1426 C CD2 . LEU A 94  ? 0.64834 0.68881 0.65407 0.00308  0.06906  0.01527  94  LEU A CD2 
1438 N N   . MET A 95  ? 0.62331 0.64044 0.55453 0.01286  0.07248  0.03256  95  MET A N   
1439 C CA  . MET A 95  ? 0.68080 0.69508 0.59852 0.01515  0.07254  0.04174  95  MET A CA  
1440 C C   . MET A 95  ? 0.67063 0.68099 0.60774 0.00692  0.06269  0.04191  95  MET A C   
1441 O O   . MET A 95  ? 0.71085 0.71439 0.63767 0.00495  0.05116  0.03251  95  MET A O   
1442 C CB  . MET A 95  ? 0.68682 0.69466 0.56683 0.02193  0.06741  0.03426  95  MET A CB  
1443 C CG  . MET A 95  ? 0.87805 0.88756 0.73538 0.03122  0.07589  0.03011  95  MET A CG  
1444 S SD  . MET A 95  ? 1.00318 1.01007 0.81517 0.04249  0.07578  0.03013  95  MET A SD  
1445 C CE  . MET A 95  ? 0.85296 0.85302 0.66209 0.03652  0.05826  0.02845  95  MET A CE  
1455 N N   . PRO A 96  ? 0.64957 0.66395 0.61723 0.00208  0.06698  0.05194  96  PRO A N   
1456 C CA  . PRO A 96  ? 0.62850 0.63783 0.61291 -0.00377 0.05932  0.05353  96  PRO A CA  
1457 C C   . PRO A 96  ? 0.60779 0.61382 0.57330 0.00129  0.05992  0.06437  96  PRO A C   
1458 O O   . PRO A 96  ? 0.59298 0.60384 0.55133 0.00715  0.07079  0.07953  96  PRO A O   
1459 C CB  . PRO A 96  ? 0.52786 0.54230 0.55143 -0.00926 0.06521  0.06215  96  PRO A CB  
1460 C CG  . PRO A 96  ? 0.64825 0.67167 0.67129 -0.00423 0.07919  0.07270  96  PRO A CG  
1461 C CD  . PRO A 96  ? 0.63485 0.65849 0.62679 0.00168  0.07886  0.06192  96  PRO A CD  
1469 N N   . LEU A 97  ? 0.78397 0.78316 0.74109 -0.00021 0.04843  0.05742  97  LEU A N   
1470 C CA  . LEU A 97  ? 0.64379 0.64064 0.58392 0.00452  0.04615  0.06697  97  LEU A CA  
1471 C C   . LEU A 97  ? 0.64855 0.64059 0.61389 -0.00060 0.04043  0.07065  97  LEU A C   
1472 O O   . LEU A 97  ? 0.56988 0.55803 0.55077 -0.00656 0.03280  0.05796  97  LEU A O   
1473 C CB  . LEU A 97  ? 0.59592 0.58948 0.50314 0.00850  0.03658  0.05566  97  LEU A CB  
1474 C CG  . LEU A 97  ? 0.68243 0.67831 0.56074 0.01508  0.04050  0.04972  97  LEU A CG  
1475 C CD1 . LEU A 97  ? 0.80517 0.79630 0.65643 0.01802  0.02809  0.03907  97  LEU A CD1 
1476 C CD2 . LEU A 97  ? 0.67353 0.67627 0.53905 0.02296  0.05395  0.06448  97  LEU A CD2 
1488 N N   . ALA A 98  ? 0.57084 0.56349 0.54028 0.00257  0.04468  0.08844  98  ALA A N   
1489 C CA  . ALA A 98  ? 0.56113 0.54822 0.55561 -0.00107 0.03979  0.09315  98  ALA A CA  
1490 C C   . ALA A 98  ? 0.68296 0.66687 0.65764 0.00201  0.02858  0.08970  98  ALA A C   
1491 O O   . ALA A 98  ? 0.75364 0.74108 0.69932 0.00909  0.02780  0.09708  98  ALA A O   
1492 C CB  . ALA A 98  ? 0.63339 0.62254 0.64792 0.00078  0.05001  0.11640  98  ALA A CB  
1498 N N   . ALA A 99  ? 0.73292 0.71117 0.72372 -0.00279 0.01978  0.07846  99  ALA A N   
1499 C CA  . ALA A 99  ? 0.63462 0.61069 0.61402 -0.00068 0.00898  0.07514  99  ALA A CA  
1500 C C   . ALA A 99  ? 0.55256 0.52316 0.56309 -0.00337 0.00640  0.07825  99  ALA A C   
1501 O O   . ALA A 99  ? 0.58817 0.55489 0.62165 -0.00875 0.00600  0.06678  99  ALA A O   
1502 C CB  . ALA A 99  ? 0.51543 0.49110 0.48040 -0.00270 0.00094  0.05577  99  ALA A CB  
1508 N N   . ARG A 100 ? 0.51937 0.48996 0.53080 0.00109  0.00459  0.09354  100 ARG A N   
1509 C CA  . ARG A 100 ? 0.50631 0.47111 0.54715 -0.00022 0.00138  0.09617  100 ARG A CA  
1510 C C   . ARG A 100 ? 0.50496 0.46913 0.54002 -0.00057 -0.00943 0.08198  100 ARG A C   
1511 O O   . ARG A 100 ? 0.51459 0.48302 0.52810 0.00348  -0.01694 0.08466  100 ARG A O   
1512 C CB  . ARG A 100 ? 0.63490 0.60062 0.68188 0.00528  0.00346  0.11982  100 ARG A CB  
1513 C CG  . ARG A 100 ? 0.68073 0.63878 0.76544 0.00394  0.00216  0.12340  100 ARG A CG  
1514 C CD  . ARG A 100 ? 0.67602 0.63167 0.78626 0.00518  0.01159  0.14539  100 ARG A CD  
1515 N NE  . ARG A 100 ? 0.82093 0.78533 0.90563 0.01258  0.01447  0.16726  100 ARG A NE  
1516 C CZ  . ARG A 100 ? 0.96879 0.93603 1.06136 0.01478  0.02584  0.18819  100 ARG A CZ  
1517 N NH1 . ARG A 100 ? 0.94754 0.90897 1.07657 0.00905  0.03476  0.19021  100 ARG A NH1 
1518 N NH2 . ARG A 100 ? 1.02513 1.00211 1.08884 0.02323  0.02823  0.20765  100 ARG A NH2 
1532 N N   . MET A 101 ? 0.61500 0.57471 0.67045 -0.00501 -0.01033 0.06723  101 MET A N   
1533 C CA  . MET A 101 ? 0.59418 0.55478 0.64618 -0.00526 -0.01814 0.05395  101 MET A CA  
1534 C C   . MET A 101 ? 0.59024 0.54914 0.65852 -0.00188 -0.02282 0.06173  101 MET A C   
1535 O O   . MET A 101 ? 0.65673 0.61085 0.74821 -0.00069 -0.01915 0.07262  101 MET A O   
1536 C CB  . MET A 101 ? 0.62350 0.58189 0.68848 -0.00969 -0.01623 0.03599  101 MET A CB  
1537 C CG  . MET A 101 ? 0.58588 0.54623 0.64191 -0.01306 -0.01134 0.03001  101 MET A CG  
1538 S SD  . MET A 101 ? 0.61825 0.58487 0.63733 -0.01144 -0.01330 0.02954  101 MET A SD  
1539 C CE  . MET A 101 ? 0.53536 0.50421 0.54718 -0.01127 -0.02185 0.01740  101 MET A CE  
1549 N N   . GLY A 102 ? 0.50188 0.46490 0.56122 -0.00033 -0.03093 0.05663  102 GLY A N   
1550 C CA  . GLY A 102 ? 0.52072 0.48425 0.59549 0.00342  -0.03634 0.06445  102 GLY A CA  
1551 C C   . GLY A 102 ? 0.50417 0.46944 0.59020 0.00296  -0.04001 0.05177  102 GLY A C   
1552 O O   . GLY A 102 ? 0.51104 0.47353 0.60757 0.00051  -0.03504 0.03816  102 GLY A O   
1556 N N   . THR A 103 ? 0.55917 0.53038 0.64308 0.00580  -0.04886 0.05659  103 THR A N   
1557 C CA  . THR A 103 ? 0.45574 0.43023 0.55579 0.00639  -0.05143 0.04849  103 THR A CA  
1558 C C   . THR A 103 ? 0.40516 0.38178 0.49589 0.00261  -0.04877 0.03218  103 THR A C   
1559 O O   . THR A 103 ? 0.39647 0.37559 0.46438 0.00008  -0.05162 0.02878  103 THR A O   
1560 C CB  . THR A 103 ? 0.51348 0.49602 0.61166 0.00921  -0.06310 0.05696  103 THR A CB  
1561 O OG1 . THR A 103 ? 0.57269 0.55460 0.68342 0.01391  -0.06553 0.07345  103 THR A OG1 
1562 C CG2 . THR A 103 ? 0.64740 0.63541 0.76317 0.00943  -0.06507 0.04937  103 THR A CG2 
1570 N N   . HIS A 104 ? 0.59534 0.57112 0.70373 0.00308  -0.04286 0.02229  104 HIS A N   
1571 C CA  . HIS A 104 ? 0.52113 0.50202 0.62398 0.00135  -0.04068 0.00980  104 HIS A CA  
1572 C C   . HIS A 104 ? 0.52189 0.51119 0.63274 0.00295  -0.04682 0.01288  104 HIS A C   
1573 O O   . HIS A 104 ? 0.54617 0.53716 0.67856 0.00681  -0.04754 0.01793  104 HIS A O   
1574 C CB  . HIS A 104 ? 0.56576 0.54438 0.68196 0.00274  -0.03182 -0.00205 104 HIS A CB  
1575 C CG  . HIS A 104 ? 0.54905 0.51987 0.66386 0.00066  -0.02700 -0.00679 104 HIS A CG  
1576 N ND1 . HIS A 104 ? 0.58931 0.56109 0.69401 -0.00165 -0.02293 -0.01908 104 HIS A ND1 
1577 C CD2 . HIS A 104 ? 0.65680 0.61951 0.78232 0.00051  -0.02586 -0.00004 104 HIS A CD2 
1578 C CE1 . HIS A 104 ? 0.64276 0.60751 0.75278 -0.00364 -0.02040 -0.02088 104 HIS A CE1 
1579 N NE2 . HIS A 104 ? 0.71012 0.66888 0.83376 -0.00258 -0.02150 -0.00910 104 HIS A NE2 
1587 N N   . ALA A 105 ? 0.46438 0.45898 0.56176 0.00005  -0.05117 0.01004  105 ALA A N   
1588 C CA  . ALA A 105 ? 0.41654 0.41975 0.52731 0.00079  -0.05692 0.01269  105 ALA A CA  
1589 C C   . ALA A 105 ? 0.43117 0.43893 0.53273 -0.00284 -0.05758 0.00652  105 ALA A C   
1590 O O   . ALA A 105 ? 0.54706 0.55100 0.62896 -0.00564 -0.05547 0.00123  105 ALA A O   
1591 C CB  . ALA A 105 ? 0.48964 0.49501 0.60189 0.00173  -0.06943 0.02361  105 ALA A CB  
1597 N N   . THR A 106 ? 0.43609 0.45246 0.55567 -0.00251 -0.05980 0.00827  106 THR A N   
1598 C CA  . THR A 106 ? 0.42853 0.44958 0.54624 -0.00631 -0.06315 0.00590  106 THR A CA  
1599 C C   . THR A 106 ? 0.54449 0.56505 0.65687 -0.00898 -0.07859 0.00942  106 THR A C   
1600 O O   . THR A 106 ? 0.69090 0.71594 0.81816 -0.00735 -0.08702 0.01612  106 THR A O   
1601 C CB  . THR A 106 ? 0.46839 0.50005 0.61175 -0.00474 -0.05803 0.00789  106 THR A CB  
1602 O OG1 . THR A 106 ? 0.54745 0.58047 0.69015 -0.00114 -0.04367 0.00291  106 THR A OG1 
1603 C CG2 . THR A 106 ? 0.71154 0.74771 0.85895 -0.00927 -0.06257 0.00791  106 THR A CG2 
1611 N N   . MET A 107 ? 0.61519 0.63080 0.70641 -0.01238 -0.08275 0.00438  107 MET A N   
1612 C CA  . MET A 107 ? 0.61537 0.62923 0.69452 -0.01382 -0.09750 0.00468  107 MET A CA  
1613 C C   . MET A 107 ? 0.65322 0.66912 0.73895 -0.01825 -0.10532 -0.00043 107 MET A C   
1614 O O   . MET A 107 ? 0.65075 0.66638 0.74053 -0.02047 -0.09745 -0.00421 107 MET A O   
1615 C CB  . MET A 107 ? 0.66126 0.66670 0.70900 -0.01297 -0.09634 0.00225  107 MET A CB  
1616 C CG  . MET A 107 ? 0.78189 0.78523 0.82494 -0.00890 -0.09329 0.01005  107 MET A CG  
1617 S SD  . MET A 107 ? 0.63409 0.62897 0.65223 -0.00847 -0.08214 0.00771  107 MET A SD  
1618 C CE  . MET A 107 ? 0.58425 0.57928 0.61616 -0.01030 -0.06849 0.00073  107 MET A CE  
1628 N N   . LYS A 108 ? 0.63874 0.65711 0.72736 -0.01929 -0.12160 -0.00013 108 LYS A N   
1629 C CA  . LYS A 108 ? 0.68288 0.70066 0.77595 -0.02385 -0.13265 -0.00722 108 LYS A CA  
1630 C C   . LYS A 108 ? 0.66055 0.66899 0.71848 -0.02327 -0.13778 -0.01561 108 LYS A C   
1631 O O   . LYS A 108 ? 0.72272 0.73081 0.76149 -0.02001 -0.14702 -0.01465 108 LYS A O   
1632 C CB  . LYS A 108 ? 0.71185 0.73818 0.82924 -0.02533 -0.14927 -0.00427 108 LYS A CB  
1633 C CG  . LYS A 108 ? 0.92090 0.95786 1.07864 -0.02623 -0.14352 0.00373  108 LYS A CG  
1634 C CD  . LYS A 108 ? 0.79960 0.83745 0.97692 -0.03085 -0.13677 0.00134  108 LYS A CD  
1635 C CE  . LYS A 108 ? 1.19702 1.23234 1.38175 -0.03651 -0.15405 -0.00642 108 LYS A CE  
1636 N NZ  . LYS A 108 ? 1.12362 1.16523 1.31825 -0.03671 -0.17439 -0.00573 108 LYS A NZ  
1650 N N   . ILE A 109 ? 0.50799 0.50975 0.55704 -0.02536 -0.13060 -0.02272 109 ILE A N   
1651 C CA  . ILE A 109 ? 0.57858 0.57142 0.59707 -0.02434 -0.13366 -0.03185 109 ILE A CA  
1652 C C   . ILE A 109 ? 0.61696 0.60590 0.64705 -0.02882 -0.14160 -0.04147 109 ILE A C   
1653 O O   . ILE A 109 ? 0.64672 0.63439 0.69194 -0.03163 -0.13232 -0.04147 109 ILE A O   
1654 C CB  . ILE A 109 ? 0.62463 0.61232 0.62384 -0.02218 -0.11730 -0.03149 109 ILE A CB  
1655 C CG1 . ILE A 109 ? 0.62700 0.61717 0.61775 -0.01818 -0.11103 -0.02248 109 ILE A CG1 
1656 C CG2 . ILE A 109 ? 0.71629 0.69545 0.68829 -0.02084 -0.11901 -0.04121 109 ILE A CG2 
1657 C CD1 . ILE A 109 ? 0.71888 0.70781 0.70943 -0.01765 -0.09436 -0.01990 109 ILE A CD1 
1669 N N   . GLN A 110 ? 0.64773 0.63512 0.67221 -0.02923 -0.15931 -0.04948 110 GLN A N   
1670 C CA  . GLN A 110 ? 0.67012 0.65175 0.70699 -0.03362 -0.16903 -0.06093 110 GLN A CA  
1671 C C   . GLN A 110 ? 0.68557 0.67272 0.76646 -0.03943 -0.16662 -0.05486 110 GLN A C   
1672 O O   . GLN A 110 ? 0.72935 0.71189 0.82416 -0.04249 -0.15961 -0.05670 110 GLN A O   
1673 C CB  . GLN A 110 ? 0.66133 0.63170 0.67620 -0.03216 -0.16038 -0.06981 110 GLN A CB  
1674 C CG  . GLN A 110 ? 0.68319 0.64918 0.65566 -0.02568 -0.16064 -0.07503 110 GLN A CG  
1675 C CD  . GLN A 110 ? 0.76914 0.72372 0.72368 -0.02406 -0.15847 -0.08820 110 GLN A CD  
1676 O OE1 . GLN A 110 ? 0.87733 0.82681 0.84852 -0.02720 -0.15076 -0.08997 110 GLN A OE1 
1677 N NE2 . GLN A 110 ? 0.88297 0.83411 0.80323 -0.01823 -0.16484 -0.09691 110 GLN A NE2 
1686 N N   . GLY A 111 ? 0.60746 0.60560 0.71187 -0.04030 -0.17160 -0.04592 111 GLY A N   
1687 C CA  . GLY A 111 ? 0.58954 0.59551 0.73745 -0.04485 -0.16853 -0.03815 111 GLY A CA  
1688 C C   . GLY A 111 ? 0.71456 0.72420 0.87079 -0.04353 -0.14648 -0.02795 111 GLY A C   
1689 O O   . GLY A 111 ? 0.90372 0.92332 1.09345 -0.04507 -0.14119 -0.01829 111 GLY A O   
1693 N N   . ARG A 112 ? 0.82619 0.82938 0.95365 -0.04027 -0.13357 -0.02970 112 ARG A N   
1694 C CA  . ARG A 112 ? 0.76176 0.76931 0.89308 -0.03823 -0.11426 -0.02162 112 ARG A CA  
1695 C C   . ARG A 112 ? 0.71571 0.72900 0.83858 -0.03353 -0.10713 -0.01544 112 ARG A C   
1696 O O   . ARG A 112 ? 0.70001 0.71019 0.80253 -0.03113 -0.11319 -0.01756 112 ARG A O   
1697 C CB  . ARG A 112 ? 0.74719 0.74596 0.85518 -0.03717 -0.10508 -0.02677 112 ARG A CB  
1698 C CG  . ARG A 112 ? 0.90927 0.90430 1.03490 -0.04087 -0.10479 -0.02840 112 ARG A CG  
1699 C CD  . ARG A 112 ? 0.97530 0.95920 1.07543 -0.03956 -0.10179 -0.03667 112 ARG A CD  
1700 N NE  . ARG A 112 ? 1.06685 1.04345 1.18436 -0.04336 -0.10785 -0.04181 112 ARG A NE  
1701 C CZ  . ARG A 112 ? 1.09490 1.07159 1.22900 -0.04429 -0.09826 -0.03611 112 ARG A CZ  
1702 N NH1 . ARG A 112 ? 1.01934 1.00397 1.15044 -0.04117 -0.08255 -0.02602 112 ARG A NH1 
1703 N NH2 . ARG A 112 ? 1.10987 1.07860 1.26453 -0.04808 -0.10512 -0.04072 112 ARG A NH2 
1717 N N   . THR A 113 ? 0.74149 0.76331 0.88065 -0.03161 -0.09377 -0.00755 113 THR A N   
1718 C CA  . THR A 113 ? 0.62541 0.65148 0.75962 -0.02672 -0.08539 -0.00338 113 THR A CA  
1719 C C   . THR A 113 ? 0.57801 0.59879 0.68609 -0.02405 -0.07347 -0.00700 113 THR A C   
1720 O O   . THR A 113 ? 0.56522 0.58594 0.67052 -0.02456 -0.06545 -0.00795 113 THR A O   
1721 C CB  . THR A 113 ? 0.64337 0.68191 0.80777 -0.02470 -0.07682 0.00518  113 THR A CB  
1722 O OG1 . THR A 113 ? 0.86156 0.90627 1.05467 -0.02760 -0.08865 0.00936  113 THR A OG1 
1723 C CG2 . THR A 113 ? 0.66694 0.70823 0.82733 -0.01897 -0.06846 0.00722  113 THR A CG2 
1731 N N   . VAL A 114 ? 0.60963 0.62665 0.70116 -0.02118 -0.07269 -0.00803 114 VAL A N   
1732 C CA  . VAL A 114 ? 0.54854 0.55990 0.61692 -0.01952 -0.06413 -0.01208 114 VAL A CA  
1733 C C   . VAL A 114 ? 0.53077 0.54292 0.59988 -0.01573 -0.05857 -0.01005 114 VAL A C   
1734 O O   . VAL A 114 ? 0.63183 0.64255 0.70276 -0.01459 -0.06517 -0.00653 114 VAL A O   
1735 C CB  . VAL A 114 ? 0.62735 0.62951 0.67132 -0.02087 -0.07072 -0.01683 114 VAL A CB  
1736 C CG1 . VAL A 114 ? 0.64547 0.64318 0.67041 -0.01878 -0.06254 -0.01844 114 VAL A CG1 
1737 C CG2 . VAL A 114 ? 0.74470 0.74377 0.78658 -0.02386 -0.07306 -0.02141 114 VAL A CG2 
1747 N N   . GLY A 115 ? 0.46325 0.47766 0.53144 -0.01341 -0.04704 -0.01246 115 GLY A N   
1748 C CA  . GLY A 115 ? 0.46844 0.48079 0.53623 -0.01015 -0.04178 -0.01361 115 GLY A CA  
1749 C C   . GLY A 115 ? 0.43842 0.44267 0.48615 -0.01134 -0.04109 -0.01696 115 GLY A C   
1750 O O   . GLY A 115 ? 0.54505 0.54816 0.57969 -0.01306 -0.03874 -0.02073 115 GLY A O   
1754 N N   . GLY A 116 ? 0.51046 0.50971 0.55832 -0.01014 -0.04280 -0.01405 116 GLY A N   
1755 C CA  . GLY A 116 ? 0.64689 0.63951 0.67977 -0.01114 -0.04124 -0.01475 116 GLY A CA  
1756 C C   . GLY A 116 ? 0.50451 0.49267 0.54332 -0.00929 -0.04275 -0.00804 116 GLY A C   
1757 O O   . GLY A 116 ? 0.56817 0.55788 0.62407 -0.00683 -0.04391 -0.00442 116 GLY A O   
1761 N N   . GLN A 117 ? 0.41677 0.39999 0.44296 -0.01001 -0.04195 -0.00506 117 GLN A N   
1762 C CA  . GLN A 117 ? 0.42298 0.40196 0.45500 -0.00814 -0.04177 0.00390  117 GLN A CA  
1763 C C   . GLN A 117 ? 0.48288 0.46079 0.49438 -0.00759 -0.04565 0.01129  117 GLN A C   
1764 O O   . GLN A 117 ? 0.50950 0.48662 0.50469 -0.00905 -0.04291 0.00765  117 GLN A O   
1765 C CB  . GLN A 117 ? 0.54621 0.52071 0.58873 -0.00890 -0.03359 0.00067  117 GLN A CB  
1766 C CG  . GLN A 117 ? 0.55739 0.52660 0.61050 -0.00740 -0.03206 0.01153  117 GLN A CG  
1767 C CD  . GLN A 117 ? 0.46313 0.42708 0.53467 -0.00876 -0.02528 0.00624  117 GLN A CD  
1768 O OE1 . GLN A 117 ? 0.47372 0.43886 0.54471 -0.01081 -0.02234 -0.00614 117 GLN A OE1 
1769 N NE2 . GLN A 117 ? 0.58778 0.54610 0.67704 -0.00742 -0.02351 0.01573  117 GLN A NE2 
1778 N N   . MET A 118 ? 0.55226 0.53106 0.56386 -0.00461 -0.05189 0.02172  118 MET A N   
1779 C CA  . MET A 118 ? 0.56601 0.54517 0.55505 -0.00233 -0.05531 0.02937  118 MET A CA  
1780 C C   . MET A 118 ? 0.54808 0.52366 0.53842 -0.00121 -0.04631 0.03842  118 MET A C   
1781 O O   . MET A 118 ? 0.57122 0.54335 0.58430 -0.00181 -0.04076 0.04115  118 MET A O   
1782 C CB  . MET A 118 ? 0.64745 0.63101 0.63404 0.00121  -0.06680 0.03770  118 MET A CB  
1783 C CG  . MET A 118 ? 0.68472 0.66858 0.68288 0.00540  -0.06699 0.05343  118 MET A CG  
1784 S SD  . MET A 118 ? 1.06785 1.05947 1.07207 0.00858  -0.08283 0.05918  118 MET A SD  
1785 C CE  . MET A 118 ? 0.94212 0.93758 0.91486 0.00779  -0.09431 0.04925  118 MET A CE  
1795 N N   . GLY A 119 ? 0.53223 0.50862 0.49935 0.00057  -0.04439 0.04237  119 GLY A N   
1796 C CA  . GLY A 119 ? 0.51990 0.49463 0.48761 0.00177  -0.03465 0.05270  119 GLY A CA  
1797 C C   . GLY A 119 ? 0.49318 0.47203 0.43253 0.00737  -0.03633 0.06252  119 GLY A C   
1798 O O   . GLY A 119 ? 0.65747 0.63924 0.57508 0.00943  -0.04536 0.05672  119 GLY A O   
1802 N N   . MET A 120 ? 0.52432 0.50373 0.46513 0.01020  -0.02754 0.07761  120 MET A N   
1803 C CA  . MET A 120 ? 0.58532 0.57032 0.49848 0.01733  -0.02648 0.09024  120 MET A CA  
1804 C C   . MET A 120 ? 0.63477 0.62034 0.54433 0.01755  -0.01241 0.09453  120 MET A C   
1805 O O   . MET A 120 ? 0.66891 0.65197 0.60518 0.01469  -0.00308 0.10281  120 MET A O   
1806 C CB  . MET A 120 ? 0.70914 0.69696 0.63000 0.02239  -0.02838 0.11057  120 MET A CB  
1807 C CG  . MET A 120 ? 0.87391 0.86982 0.76090 0.03072  -0.03665 0.11852  120 MET A CG  
1808 S SD  . MET A 120 ? 1.39997 1.40087 1.29722 0.03772  -0.03664 0.14693  120 MET A SD  
1809 C CE  . MET A 120 ? 0.92599 0.92478 0.83937 0.03742  -0.01589 0.16308  120 MET A CE  
1819 N N   . LEU A 121 ? 0.67415 0.66278 0.55401 0.02075  -0.01103 0.08787  121 LEU A N   
1820 C CA  . LEU A 121 ? 0.62655 0.61745 0.50299 0.02208  0.00315  0.09296  121 LEU A CA  
1821 C C   . LEU A 121 ? 0.80205 0.79843 0.67746 0.02841  0.01222  0.11729  121 LEU A C   
1822 O O   . LEU A 121 ? 0.94156 0.94305 0.79394 0.03591  0.00724  0.12715  121 LEU A O   
1823 C CB  . LEU A 121 ? 0.61169 0.60458 0.45564 0.02582  0.00292  0.08053  121 LEU A CB  
1824 C CG  . LEU A 121 ? 0.62098 0.60860 0.47322 0.01901  -0.00155 0.05971  121 LEU A CG  
1825 C CD1 . LEU A 121 ? 0.71461 0.70239 0.53635 0.02321  -0.00423 0.04678  121 LEU A CD1 
1826 C CD2 . LEU A 121 ? 0.60057 0.58702 0.48063 0.01302  0.00876  0.05918  121 LEU A CD2 
1838 N N   . LEU A 122 ? 0.85742 0.85354 0.75930 0.02550  0.02510  0.12770  122 LEU A N   
1839 C CA  . LEU A 122 ? 0.93741 0.93887 0.84552 0.03084  0.03619  0.15355  122 LEU A CA  
1840 C C   . LEU A 122 ? 1.05865 1.06830 0.94388 0.03723  0.04945  0.16011  122 LEU A C   
1841 O O   . LEU A 122 ? 0.87293 0.88202 0.76530 0.03332  0.05591  0.14980  122 LEU A O   
1842 C CB  . LEU A 122 ? 0.78201 0.77800 0.73881 0.02356  0.04248  0.16185  122 LEU A CB  
1843 C CG  . LEU A 122 ? 0.73461 0.72203 0.71755 0.01817  0.03157  0.15516  122 LEU A CG  
1844 C CD1 . LEU A 122 ? 0.70426 0.68436 0.73248 0.00951  0.03597  0.15125  122 LEU A CD1 
1845 C CD2 . LEU A 122 ? 0.79654 0.78594 0.77903 0.02456  0.02834  0.17550  122 LEU A CD2 
1857 N N   . THR A 123 ? 1.26063 1.27893 1.11813 0.04791  0.05365  0.17779  123 THR A N   
1858 C CA  . THR A 123 ? 1.35535 1.38342 1.18902 0.05658  0.06858  0.18781  123 THR A CA  
1859 C C   . THR A 123 ? 1.48765 1.51422 1.30627 0.05516  0.06986  0.16519  123 THR A C   
1860 O O   . THR A 123 ? 1.32596 1.35045 1.11314 0.05785  0.05874  0.14651  123 THR A O   
1861 C CB  . THR A 123 ? 1.38197 1.41437 1.25036 0.05563  0.08689  0.21251  123 THR A CB  
1862 O OG1 . THR A 123 ? 1.37526 1.41824 1.22249 0.06408  0.10305  0.22109  123 THR A OG1 
1863 C CG2 . THR A 123 ? 1.20162 1.22538 1.11808 0.04245  0.08742  0.20266  123 THR A CG2 
1871 N N   . LEU A 132 ? 1.31284 1.33316 1.04011 0.06657  0.07365  0.07871  132 LEU A N   
1872 C CA  . LEU A 132 ? 1.32783 1.34358 1.01859 0.07199  0.05965  0.06179  132 LEU A CA  
1873 C C   . LEU A 132 ? 1.28545 1.29338 0.98811 0.06304  0.03998  0.05325  132 LEU A C   
1874 O O   . LEU A 132 ? 1.34551 1.35576 1.04070 0.06464  0.03200  0.06233  132 LEU A O   
1875 C CB  . LEU A 132 ? 1.36720 1.37818 1.04559 0.07483  0.06114  0.04116  132 LEU A CB  
1876 C CG  . LEU A 132 ? 1.46042 1.46563 1.10254 0.08093  0.04698  0.02113  132 LEU A CG  
1877 C CD1 . LEU A 132 ? 1.43870 1.44629 1.05089 0.09333  0.05816  0.01299  132 LEU A CD1 
1878 C CD2 . LEU A 132 ? 1.35627 1.34988 1.01718 0.07058  0.03161  0.00198  132 LEU A CD2 
1889 N N   . GLY A 133 ? 1.32574 1.32550 1.04811 0.05421  0.03279  0.03714  133 GLY A N   
1890 C CA  . GLY A 133 ? 1.06126 1.05465 0.79577 0.04641  0.01573  0.02882  133 GLY A CA  
1891 C C   . GLY A 133 ? 0.99072 0.97692 0.74399 0.03872  0.01161  0.01232  133 GLY A C   
1892 O O   . GLY A 133 ? 1.02977 1.01641 0.79201 0.03829  0.02197  0.00990  133 GLY A O   
1896 N N   . THR A 134 ? 0.91513 0.89589 0.67582 0.03306  -0.00326 0.00242  134 THR A N   
1897 C CA  . THR A 134 ? 0.74891 0.72371 0.52665 0.02651  -0.00741 -0.01149 134 THR A CA  
1898 C C   . THR A 134 ? 0.74054 0.70923 0.49865 0.02987  -0.01657 -0.02859 134 THR A C   
1899 O O   . THR A 134 ? 0.75955 0.72805 0.49386 0.03512  -0.02539 -0.03221 134 THR A O   
1900 C CB  . THR A 134 ? 0.63267 0.60599 0.43641 0.01795  -0.01600 -0.01089 134 THR A CB  
1901 O OG1 . THR A 134 ? 0.73848 0.71232 0.53380 0.01920  -0.02759 -0.00839 134 THR A OG1 
1902 C CG2 . THR A 134 ? 0.60518 0.58219 0.43370 0.01362  -0.00703 0.00072  134 THR A CG2 
1910 N N   . THR A 135 ? 0.82881 0.79250 0.59873 0.02685  -0.01527 -0.03938 135 THR A N   
1911 C CA  . THR A 135 ? 0.82479 0.78068 0.58261 0.02923  -0.02396 -0.05646 135 THR A CA  
1912 C C   . THR A 135 ? 0.80258 0.75294 0.58619 0.02124  -0.03127 -0.06432 135 THR A C   
1913 O O   . THR A 135 ? 0.78627 0.74003 0.59333 0.01464  -0.02970 -0.05674 135 THR A O   
1914 C CB  . THR A 135 ? 0.87489 0.82917 0.61659 0.03713  -0.01291 -0.06251 135 THR A CB  
1915 O OG1 . THR A 135 ? 0.84486 0.79991 0.60984 0.03357  -0.00273 -0.05997 135 THR A OG1 
1916 C CG2 . THR A 135 ? 0.94649 0.90852 0.66421 0.04584  -0.00240 -0.05177 135 THR A CG2 
1924 N N   . PRO A 136 ? 0.65658 0.59859 0.43756 0.02202  -0.03905 -0.07929 136 PRO A N   
1925 C CA  . PRO A 136 ? 0.71697 0.65458 0.52531 0.01454  -0.04547 -0.08389 136 PRO A CA  
1926 C C   . PRO A 136 ? 0.78477 0.72373 0.61402 0.01174  -0.03485 -0.07974 136 PRO A C   
1927 O O   . PRO A 136 ? 0.73421 0.67351 0.58669 0.00558  -0.03820 -0.07793 136 PRO A O   
1928 C CB  . PRO A 136 ? 0.67734 0.60472 0.47816 0.01692  -0.05612 -0.10105 136 PRO A CB  
1929 C CG  . PRO A 136 ? 0.68148 0.60992 0.45066 0.02375  -0.06176 -0.10520 136 PRO A CG  
1930 C CD  . PRO A 136 ? 0.70614 0.64281 0.45962 0.02920  -0.04652 -0.09245 136 PRO A CD  
1938 N N   . GLY A 137 ? 0.75285 0.69374 0.57544 0.01653  -0.02238 -0.07768 137 GLY A N   
1939 C CA  . GLY A 137 ? 0.79014 0.73452 0.63371 0.01386  -0.01400 -0.07265 137 GLY A CA  
1940 C C   . GLY A 137 ? 0.69315 0.64694 0.55130 0.00860  -0.01077 -0.06061 137 GLY A C   
1941 O O   . GLY A 137 ? 0.67239 0.63035 0.54841 0.00579  -0.00677 -0.05719 137 GLY A O   
1945 N N   . ASP A 138 ? 0.60368 0.56077 0.45515 0.00759  -0.01332 -0.05468 138 ASP A N   
1946 C CA  . ASP A 138 ? 0.48051 0.44539 0.34373 0.00427  -0.00836 -0.04410 138 ASP A CA  
1947 C C   . ASP A 138 ? 0.50236 0.46935 0.38400 -0.00199 -0.01454 -0.04261 138 ASP A C   
1948 O O   . ASP A 138 ? 0.47914 0.45191 0.37335 -0.00480 -0.01077 -0.03679 138 ASP A O   
1949 C CB  . ASP A 138 ? 0.50818 0.47537 0.35755 0.00723  -0.00637 -0.03652 138 ASP A CB  
1950 C CG  . ASP A 138 ? 0.58895 0.55717 0.42043 0.01448  0.00309  -0.03502 138 ASP A CG  
1951 O OD1 . ASP A 138 ? 0.60403 0.57275 0.43946 0.01641  0.01041  -0.03802 138 ASP A OD1 
1952 O OD2 . ASP A 138 ? 0.59395 0.56345 0.40758 0.01895  0.00358  -0.02992 138 ASP A OD2 
1957 N N   . CYS A 139 ? 0.55289 0.51574 0.43789 -0.00394 -0.02365 -0.04803 139 CYS A N   
1958 C CA  . CYS A 139 ? 0.44235 0.40871 0.34564 -0.00875 -0.02740 -0.04581 139 CYS A CA  
1959 C C   . CYS A 139 ? 0.38758 0.35985 0.30412 -0.01021 -0.02068 -0.04360 139 CYS A C   
1960 O O   . CYS A 139 ? 0.36790 0.33950 0.28507 -0.00854 -0.01693 -0.04578 139 CYS A O   
1961 C CB  . CYS A 139 ? 0.43165 0.39352 0.34093 -0.01045 -0.03652 -0.05112 139 CYS A CB  
1962 S SG  . CYS A 139 ? 0.60461 0.56294 0.50242 -0.00965 -0.04796 -0.05331 139 CYS A SG  
1967 N N   . GLY A 140 ? 0.46760 0.44597 0.39446 -0.01266 -0.01951 -0.03968 140 GLY A N   
1968 C CA  . GLY A 140 ? 0.46814 0.45388 0.40556 -0.01360 -0.01496 -0.03860 140 GLY A CA  
1969 C C   . GLY A 140 ? 0.52793 0.51797 0.46795 -0.01402 -0.01019 -0.03617 140 GLY A C   
1970 O O   . GLY A 140 ? 0.43653 0.43332 0.38653 -0.01541 -0.00924 -0.03672 140 GLY A O   
1974 N N   . CYS A 141 ? 0.51381 0.50074 0.44595 -0.01256 -0.00722 -0.03338 141 CYS A N   
1975 C CA  . CYS A 141 ? 0.46469 0.45571 0.40450 -0.01346 -0.00208 -0.02943 141 CYS A CA  
1976 C C   . CYS A 141 ? 0.49100 0.48256 0.44166 -0.01623 -0.00467 -0.02821 141 CYS A C   
1977 O O   . CYS A 141 ? 0.51762 0.50533 0.46540 -0.01619 -0.00905 -0.02752 141 CYS A O   
1978 C CB  . CYS A 141 ? 0.59472 0.58331 0.52416 -0.01034 0.00338  -0.02421 141 CYS A CB  
1979 S SG  . CYS A 141 ? 0.51839 0.50663 0.43742 -0.00577 0.00868  -0.02696 141 CYS A SG  
1985 N N   . PRO A 142 ? 0.49950 0.49573 0.46468 -0.01848 -0.00257 -0.02854 142 PRO A N   
1986 C CA  . PRO A 142 ? 0.47406 0.46997 0.45207 -0.02073 -0.00528 -0.03028 142 PRO A CA  
1987 C C   . PRO A 142 ? 0.52010 0.51140 0.50488 -0.02124 -0.00304 -0.02285 142 PRO A C   
1988 O O   . PRO A 142 ? 0.48996 0.48113 0.47360 -0.02044 0.00225  -0.01559 142 PRO A O   
1989 C CB  . PRO A 142 ? 0.43097 0.43419 0.42184 -0.02267 -0.00540 -0.03615 142 PRO A CB  
1990 C CG  . PRO A 142 ? 0.43745 0.44389 0.42840 -0.02232 -0.00062 -0.03212 142 PRO A CG  
1991 C CD  . PRO A 142 ? 0.52749 0.52990 0.50026 -0.01894 0.00157  -0.02856 142 PRO A CD  
1999 N N   . TYR A 143 ? 0.45858 0.44662 0.45144 -0.02186 -0.00631 -0.02357 143 TYR A N   
2000 C CA  . TYR A 143 ? 0.40349 0.38712 0.40943 -0.02249 -0.00461 -0.01636 143 TYR A CA  
2001 C C   . TYR A 143 ? 0.38606 0.37073 0.41491 -0.02574 -0.00473 -0.02292 143 TYR A C   
2002 O O   . TYR A 143 ? 0.39973 0.38677 0.43139 -0.02599 -0.00846 -0.03371 143 TYR A O   
2003 C CB  . TYR A 143 ? 0.47572 0.45497 0.47956 -0.02061 -0.00869 -0.01334 143 TYR A CB  
2004 C CG  . TYR A 143 ? 0.43246 0.41045 0.41593 -0.01748 -0.01056 -0.00664 143 TYR A CG  
2005 C CD1 . TYR A 143 ? 0.47384 0.45342 0.44131 -0.01652 -0.01379 -0.01214 143 TYR A CD1 
2006 C CD2 . TYR A 143 ? 0.43573 0.41110 0.41684 -0.01513 -0.00978 0.00505  143 TYR A CD2 
2007 C CE1 . TYR A 143 ? 0.53120 0.50900 0.48082 -0.01370 -0.01734 -0.00878 143 TYR A CE1 
2008 C CE2 . TYR A 143 ? 0.52682 0.50213 0.48670 -0.01151 -0.01310 0.00958  143 TYR A CE2 
2009 C CZ  . TYR A 143 ? 0.51293 0.48907 0.45713 -0.01100 -0.01747 0.00127  143 TYR A CZ  
2010 O OH  . TYR A 143 ? 0.51024 0.48574 0.43397 -0.00743 -0.02250 0.00314  143 TYR A OH  
2020 N N   . ILE A 144 ? 0.55505 0.53859 0.60066 -0.02786 -0.00069 -0.01668 144 ILE A N   
2021 C CA  . ILE A 144 ? 0.49837 0.48241 0.56957 -0.03170 -0.00200 -0.02393 144 ILE A CA  
2022 C C   . ILE A 144 ? 0.54185 0.51934 0.63614 -0.03325 0.00145  -0.01357 144 ILE A C   
2023 O O   . ILE A 144 ? 0.61772 0.59460 0.70840 -0.03176 0.00743  0.00164  144 ILE A O   
2024 C CB  . ILE A 144 ? 0.51444 0.50662 0.58970 -0.03397 -0.00098 -0.02740 144 ILE A CB  
2025 C CG1 . ILE A 144 ? 0.53141 0.53019 0.58560 -0.03180 -0.00413 -0.03567 144 ILE A CG1 
2026 C CG2 . ILE A 144 ? 0.64014 0.63334 0.74438 -0.03847 -0.00442 -0.03591 144 ILE A CG2 
2027 C CD1 . ILE A 144 ? 0.59428 0.60272 0.65289 -0.03320 -0.00427 -0.03913 144 ILE A CD1 
2039 N N   . TYR A 145 ? 0.50585 0.47850 0.62392 -0.03553 -0.00197 -0.02159 145 TYR A N   
2040 C CA  . TYR A 145 ? 0.48422 0.44978 0.63239 -0.03781 0.00099  -0.01277 145 TYR A CA  
2041 C C   . TYR A 145 ? 0.54589 0.51045 0.72318 -0.04261 -0.00362 -0.02741 145 TYR A C   
2042 O O   . TYR A 145 ? 0.68275 0.65048 0.85339 -0.04238 -0.01007 -0.04544 145 TYR A O   
2043 C CB  . TYR A 145 ? 0.54701 0.50440 0.69667 -0.03436 0.00083  -0.00591 145 TYR A CB  
2044 C CG  . TYR A 145 ? 0.49613 0.44817 0.65615 -0.03348 -0.00473 -0.02113 145 TYR A CG  
2045 C CD1 . TYR A 145 ? 0.43564 0.39166 0.57369 -0.03035 -0.00862 -0.03263 145 TYR A CD1 
2046 C CD2 . TYR A 145 ? 0.53077 0.47371 0.72436 -0.03519 -0.00517 -0.02342 145 TYR A CD2 
2047 C CE1 . TYR A 145 ? 0.46222 0.41467 0.60904 -0.02820 -0.01187 -0.04601 145 TYR A CE1 
2048 C CE2 . TYR A 145 ? 0.52604 0.46376 0.72870 -0.03316 -0.00935 -0.03867 145 TYR A CE2 
2049 C CZ  . TYR A 145 ? 0.45671 0.39985 0.63467 -0.02925 -0.01219 -0.04978 145 TYR A CZ  
2050 O OH  . TYR A 145 ? 0.61279 0.55194 0.79925 -0.02596 -0.01462 -0.06450 145 TYR A OH  
2060 N N   . LYS A 146 ? 0.51390 0.47526 0.72363 -0.04679 -0.00040 -0.01931 146 LYS A N   
2061 C CA  . LYS A 146 ? 0.59669 0.55629 0.83975 -0.05222 -0.00611 -0.03343 146 LYS A CA  
2062 C C   . LYS A 146 ? 0.62877 0.57558 0.89580 -0.05209 -0.00888 -0.03945 146 LYS A C   
2063 O O   . LYS A 146 ? 0.55652 0.49564 0.83774 -0.05112 -0.00313 -0.02277 146 LYS A O   
2064 C CB  . LYS A 146 ? 0.60099 0.56379 0.87429 -0.05760 -0.00147 -0.02173 146 LYS A CB  
2065 C CG  . LYS A 146 ? 0.80973 0.77294 1.11763 -0.06404 -0.01010 -0.03915 146 LYS A CG  
2066 C CD  . LYS A 146 ? 0.90566 0.87707 1.24022 -0.06951 -0.00652 -0.02904 146 LYS A CD  
2067 C CE  . LYS A 146 ? 0.92893 0.89207 1.31216 -0.07447 -0.00158 -0.01541 146 LYS A CE  
2068 N NZ  . LYS A 146 ? 0.80058 0.77382 1.21050 -0.07926 0.00404  -0.00223 146 LYS A NZ  
2082 N N   . ARG A 147 ? 0.75549 0.70051 1.02739 -0.05231 -0.01743 -0.06296 147 ARG A N   
2083 C CA  . ARG A 147 ? 0.78359 0.71592 1.07981 -0.05148 -0.02050 -0.07324 147 ARG A CA  
2084 C C   . ARG A 147 ? 0.83111 0.76067 1.16215 -0.05728 -0.02834 -0.09139 147 ARG A C   
2085 O O   . ARG A 147 ? 0.91991 0.85602 1.23981 -0.05694 -0.03679 -0.11344 147 ARG A O   
2086 C CB  . ARG A 147 ? 0.71161 0.64420 0.98045 -0.04471 -0.02318 -0.08681 147 ARG A CB  
2087 C CG  . ARG A 147 ? 0.73831 0.65855 1.03068 -0.04244 -0.02593 -0.10050 147 ARG A CG  
2088 C CD  . ARG A 147 ? 0.62548 0.54778 0.89050 -0.03462 -0.02566 -0.10904 147 ARG A CD  
2089 N NE  . ARG A 147 ? 0.58953 0.52362 0.82674 -0.03222 -0.03044 -0.12732 147 ARG A NE  
2090 C CZ  . ARG A 147 ? 0.64180 0.58346 0.84793 -0.02602 -0.02856 -0.12929 147 ARG A CZ  
2091 N NH1 . ARG A 147 ? 0.63176 0.57092 0.83054 -0.02220 -0.02323 -0.11545 147 ARG A NH1 
2092 N NH2 . ARG A 147 ? 0.78587 0.73892 0.96930 -0.02345 -0.03237 -0.14446 147 ARG A NH2 
2106 N N   . GLY A 148 ? 0.76414 0.68450 1.13834 -0.06236 -0.02604 -0.08187 148 GLY A N   
2107 C CA  . GLY A 148 ? 0.73328 0.65141 1.14612 -0.06929 -0.03416 -0.09730 148 GLY A CA  
2108 C C   . GLY A 148 ? 0.89245 0.82587 1.29985 -0.07375 -0.03638 -0.09597 148 GLY A C   
2109 O O   . GLY A 148 ? 0.82873 0.76726 1.24227 -0.07612 -0.02766 -0.07268 148 GLY A O   
2113 N N   . ASN A 149 ? 0.81556 0.75757 1.21065 -0.07399 -0.04759 -0.12006 149 ASN A N   
2114 C CA  . ASN A 149 ? 0.81477 0.77257 1.20578 -0.07759 -0.05105 -0.11974 149 ASN A CA  
2115 C C   . ASN A 149 ? 0.81202 0.78316 1.15147 -0.07142 -0.05116 -0.12239 149 ASN A C   
2116 O O   . ASN A 149 ? 0.80734 0.79227 1.14036 -0.07318 -0.05330 -0.12057 149 ASN A O   
2117 C CB  . ASN A 149 ? 0.88774 0.84761 1.31097 -0.08350 -0.06585 -0.14386 149 ASN A CB  
2118 C CG  . ASN A 149 ? 0.99228 0.93813 1.47386 -0.09071 -0.06683 -0.14242 149 ASN A CG  
2119 O OD1 . ASN A 149 ? 1.01462 0.96391 1.53265 -0.09789 -0.06443 -0.12864 149 ASN A OD1 
2120 N ND2 . ASN A 149 ? 0.97514 0.90519 1.46849 -0.08852 -0.06967 -0.15591 149 ASN A ND2 
2127 N N   . ASP A 150 ? 0.89674 0.86452 1.20271 -0.06424 -0.04856 -0.12538 150 ASP A N   
2128 C CA  . ASP A 150 ? 0.74758 0.72721 1.00879 -0.05843 -0.04890 -0.12842 150 ASP A CA  
2129 C C   . ASP A 150 ? 0.73162 0.71052 0.96824 -0.05495 -0.03742 -0.10606 150 ASP A C   
2130 O O   . ASP A 150 ? 0.70353 0.67163 0.94490 -0.05343 -0.03135 -0.09567 150 ASP A O   
2131 C CB  . ASP A 150 ? 0.77774 0.75681 1.01831 -0.05217 -0.05474 -0.14955 150 ASP A CB  
2132 C CG  . ASP A 150 ? 0.84377 0.81967 1.10879 -0.05421 -0.06626 -0.17452 150 ASP A CG  
2133 O OD1 . ASP A 150 ? 0.93591 0.91304 1.23272 -0.06129 -0.07240 -0.17763 150 ASP A OD1 
2134 O OD2 . ASP A 150 ? 1.02750 0.99976 1.28118 -0.04840 -0.06922 -0.19175 150 ASP A OD2 
2139 N N   . TYR A 151 ? 0.84329 0.83370 1.05416 -0.05325 -0.03532 -0.09949 151 TYR A N   
2140 C CA  . TYR A 151 ? 0.71823 0.70818 0.90119 -0.04905 -0.02674 -0.08339 151 TYR A CA  
2141 C C   . TYR A 151 ? 0.64379 0.63355 0.79910 -0.04305 -0.02844 -0.09210 151 TYR A C   
2142 O O   . TYR A 151 ? 0.66819 0.66425 0.81441 -0.04084 -0.03494 -0.10858 151 TYR A O   
2143 C CB  . TYR A 151 ? 0.79425 0.79513 0.96292 -0.04908 -0.02350 -0.07406 151 TYR A CB  
2144 C CG  . TYR A 151 ? 0.87146 0.87276 1.06446 -0.05337 -0.01744 -0.05929 151 TYR A CG  
2145 C CD1 . TYR A 151 ? 0.90091 0.89497 1.09620 -0.05250 -0.00795 -0.04091 151 TYR A CD1 
2146 C CD2 . TYR A 151 ? 1.01978 1.03031 1.23384 -0.05768 -0.02096 -0.06257 151 TYR A CD2 
2147 C CE1 . TYR A 151 ? 0.91758 0.91363 1.13418 -0.05525 -0.00041 -0.02530 151 TYR A CE1 
2148 C CE2 . TYR A 151 ? 1.20473 1.21711 1.44372 -0.06122 -0.01380 -0.04733 151 TYR A CE2 
2149 C CZ  . TYR A 151 ? 1.06422 1.06937 1.30378 -0.05972 -0.00267 -0.02828 151 TYR A CZ  
2150 O OH  . TYR A 151 ? 1.09669 1.10515 1.36030 -0.06213 0.00641  -0.01107 151 TYR A OH  
2160 N N   . VAL A 152 ? 0.72116 0.70478 0.86392 -0.03998 -0.02254 -0.08022 152 VAL A N   
2161 C CA  . VAL A 152 ? 0.49005 0.47359 0.61116 -0.03452 -0.02277 -0.08484 152 VAL A CA  
2162 C C   . VAL A 152 ? 0.45452 0.44087 0.55115 -0.03234 -0.01815 -0.07077 152 VAL A C   
2163 O O   . VAL A 152 ? 0.43363 0.41518 0.53213 -0.03313 -0.01364 -0.05605 152 VAL A O   
2164 C CB  . VAL A 152 ? 0.46232 0.43475 0.59836 -0.03277 -0.02199 -0.08615 152 VAL A CB  
2165 C CG1 . VAL A 152 ? 0.52119 0.49576 0.63747 -0.02682 -0.02160 -0.09064 152 VAL A CG1 
2166 C CG2 . VAL A 152 ? 0.51045 0.47779 0.67464 -0.03521 -0.02687 -0.10138 152 VAL A CG2 
2176 N N   . VAL A 153 ? 0.51464 0.50902 0.58900 -0.02930 -0.01937 -0.07514 153 VAL A N   
2177 C CA  . VAL A 153 ? 0.51352 0.50930 0.56684 -0.02713 -0.01631 -0.06467 153 VAL A CA  
2178 C C   . VAL A 153 ? 0.53504 0.52784 0.58226 -0.02351 -0.01635 -0.06503 153 VAL A C   
2179 O O   . VAL A 153 ? 0.54450 0.54075 0.59127 -0.02075 -0.01792 -0.07549 153 VAL A O   
2180 C CB  . VAL A 153 ? 0.57797 0.58386 0.61542 -0.02611 -0.01708 -0.06688 153 VAL A CB  
2181 C CG1 . VAL A 153 ? 0.62815 0.64209 0.66156 -0.02345 -0.02086 -0.07983 153 VAL A CG1 
2182 C CG2 . VAL A 153 ? 0.51637 0.52169 0.53543 -0.02396 -0.01463 -0.05795 153 VAL A CG2 
2192 N N   . ILE A 154 ? 0.62997 0.61767 0.67214 -0.02288 -0.01467 -0.05354 154 ILE A N   
2193 C CA  . ILE A 154 ? 0.57822 0.56313 0.62041 -0.01991 -0.01536 -0.05185 154 ILE A CA  
2194 C C   . ILE A 154 ? 0.52142 0.51009 0.54653 -0.01815 -0.01619 -0.04722 154 ILE A C   
2195 O O   . ILE A 154 ? 0.51335 0.50268 0.54017 -0.01566 -0.01707 -0.04698 154 ILE A O   
2196 C CB  . ILE A 154 ? 0.58857 0.56483 0.64379 -0.02025 -0.01473 -0.04210 154 ILE A CB  
2197 C CG1 . ILE A 154 ? 0.45633 0.43143 0.49986 -0.02107 -0.01358 -0.02904 154 ILE A CG1 
2198 C CG2 . ILE A 154 ? 0.55281 0.52410 0.63109 -0.02235 -0.01392 -0.04691 154 ILE A CG2 
2199 C CD1 . ILE A 154 ? 0.54562 0.51442 0.59841 -0.02014 -0.01280 -0.01643 154 ILE A CD1 
2211 N N   . GLY A 155 ? 0.50353 0.49458 0.51507 -0.01924 -0.01593 -0.04375 155 GLY A N   
2212 C CA  . GLY A 155 ? 0.39337 0.38612 0.39260 -0.01806 -0.01762 -0.04026 155 GLY A CA  
2213 C C   . GLY A 155 ? 0.45338 0.44609 0.44002 -0.01898 -0.01682 -0.03726 155 GLY A C   
2214 O O   . GLY A 155 ? 0.44148 0.43512 0.42934 -0.02020 -0.01416 -0.03778 155 GLY A O   
2218 N N   . VAL A 156 ? 0.55978 0.55136 0.53662 -0.01823 -0.01930 -0.03461 156 VAL A N   
2219 C CA  . VAL A 156 ? 0.50090 0.49117 0.46549 -0.01805 -0.01854 -0.03341 156 VAL A CA  
2220 C C   . VAL A 156 ? 0.44604 0.43089 0.40087 -0.01703 -0.02293 -0.02988 156 VAL A C   
2221 O O   . VAL A 156 ? 0.52340 0.50780 0.48213 -0.01702 -0.02793 -0.02932 156 VAL A O   
2222 C CB  . VAL A 156 ? 0.47188 0.46698 0.43510 -0.01771 -0.01789 -0.03687 156 VAL A CB  
2223 C CG1 . VAL A 156 ? 0.46465 0.46695 0.43362 -0.01784 -0.01472 -0.04047 156 VAL A CG1 
2224 C CG2 . VAL A 156 ? 0.45484 0.45166 0.42306 -0.01738 -0.02098 -0.03682 156 VAL A CG2 
2234 N N   . HIS A 157 ? 0.46366 0.44545 0.40588 -0.01562 -0.02129 -0.02786 157 HIS A N   
2235 C CA  . HIS A 157 ? 0.50265 0.48008 0.43159 -0.01352 -0.02621 -0.02573 157 HIS A CA  
2236 C C   . HIS A 157 ? 0.50532 0.48116 0.43301 -0.01403 -0.03312 -0.03102 157 HIS A C   
2237 O O   . HIS A 157 ? 0.48280 0.45900 0.41244 -0.01463 -0.03154 -0.03531 157 HIS A O   
2238 C CB  . HIS A 157 ? 0.48161 0.45733 0.39481 -0.01048 -0.02140 -0.02382 157 HIS A CB  
2239 C CG  . HIS A 157 ? 0.45613 0.42867 0.35114 -0.00682 -0.02633 -0.02202 157 HIS A CG  
2240 N ND1 . HIS A 157 ? 0.53294 0.50596 0.42683 -0.00557 -0.02963 -0.01447 157 HIS A ND1 
2241 C CD2 . HIS A 157 ? 0.52734 0.49656 0.40394 -0.00345 -0.02921 -0.02740 157 HIS A CD2 
2242 C CE1 . HIS A 157 ? 0.71886 0.69039 0.59239 -0.00142 -0.03489 -0.01469 157 HIS A CE1 
2243 N NE2 . HIS A 157 ? 0.65325 0.62203 0.51540 -0.00007 -0.03490 -0.02372 157 HIS A NE2 
2251 N N   . THR A 158 ? 0.53160 0.50609 0.45889 -0.01382 -0.04121 -0.02986 158 THR A N   
2252 C CA  . THR A 158 ? 0.52298 0.49616 0.45445 -0.01515 -0.04880 -0.03475 158 THR A CA  
2253 C C   . THR A 158 ? 0.52945 0.49870 0.44707 -0.01324 -0.05859 -0.03718 158 THR A C   
2254 O O   . THR A 158 ? 0.55265 0.51828 0.46935 -0.01389 -0.06479 -0.04420 158 THR A O   
2255 C CB  . THR A 158 ? 0.55374 0.53174 0.50582 -0.01744 -0.05082 -0.03245 158 THR A CB  
2256 O OG1 . THR A 158 ? 0.72314 0.70080 0.68456 -0.01934 -0.05658 -0.03574 158 THR A OG1 
2257 C CG2 . THR A 158 ? 0.67411 0.65339 0.62973 -0.01656 -0.05593 -0.02724 158 THR A CG2 
2265 N N   . ALA A 159 ? 0.51110 0.48116 0.41840 -0.01056 -0.06062 -0.03160 159 ALA A N   
2266 C CA  . ALA A 159 ? 0.54116 0.50959 0.43294 -0.00780 -0.07161 -0.03390 159 ALA A CA  
2267 C C   . ALA A 159 ? 0.62238 0.59280 0.49742 -0.00304 -0.06932 -0.02499 159 ALA A C   
2268 O O   . ALA A 159 ? 0.66421 0.63650 0.54546 -0.00294 -0.05980 -0.01650 159 ALA A O   
2269 C CB  . ALA A 159 ? 0.64762 0.61855 0.55608 -0.01054 -0.08373 -0.03452 159 ALA A CB  
2275 N N   . ALA A 160 ? 0.55292 0.52328 0.40732 0.00119  -0.07872 -0.02696 160 ALA A N   
2276 C CA  . ALA A 160 ? 0.60638 0.58009 0.44041 0.00737  -0.07742 -0.01719 160 ALA A CA  
2277 C C   . ALA A 160 ? 0.74711 0.72274 0.56341 0.01116  -0.09341 -0.02138 160 ALA A C   
2278 O O   . ALA A 160 ? 0.73952 0.71144 0.55014 0.01038  -0.10273 -0.03540 160 ALA A O   
2279 C CB  . ALA A 160 ? 0.68560 0.65819 0.49989 0.01187  -0.06462 -0.01605 160 ALA A CB  
2285 N N   . ALA A 161 ? 0.88020 0.86177 0.68907 0.01546  -0.09708 -0.00904 161 ALA A N   
2286 C CA  . ALA A 161 ? 0.86355 0.84951 0.65573 0.01969  -0.11403 -0.01120 161 ALA A CA  
2287 C C   . ALA A 161 ? 1.08011 1.06532 0.83368 0.02720  -0.11595 -0.01990 161 ALA A C   
2288 O O   . ALA A 161 ? 0.99589 0.98250 0.72955 0.03311  -0.10284 -0.01242 161 ALA A O   
2289 C CB  . ALA A 161 ? 0.96029 0.95396 0.75466 0.02351  -0.11610 0.00716  161 ALA A CB  
2295 N N   . ARG A 162 ? 1.28016 1.26360 1.02439 0.02737  -0.13252 -0.03595 162 ARG A N   
2296 C CA  . ARG A 162 ? 1.33384 1.31659 1.03889 0.03578  -0.13691 -0.04726 162 ARG A CA  
2297 C C   . ARG A 162 ? 1.49641 1.48894 1.17031 0.04614  -0.13445 -0.03227 162 ARG A C   
2298 O O   . ARG A 162 ? 1.50978 1.50315 1.15282 0.05445  -0.12395 -0.03217 162 ARG A O   
2299 C CB  . ARG A 162 ? 1.38470 1.36516 1.08798 0.03424  -0.15936 -0.06634 162 ARG A CB  
2300 C CG  . ARG A 162 ? 1.47616 1.45019 1.14864 0.04026  -0.16254 -0.08657 162 ARG A CG  
2301 C CD  . ARG A 162 ? 1.74691 1.70952 1.44561 0.03200  -0.16733 -0.10447 162 ARG A CD  
2302 N NE  . ARG A 162 ? 1.83847 1.79211 1.51450 0.03738  -0.16284 -0.12185 162 ARG A NE  
2303 C CZ  . ARG A 162 ? 1.90956 1.85170 1.60542 0.03213  -0.16226 -0.13626 162 ARG A CZ  
2304 N NH1 . ARG A 162 ? 1.72057 1.65966 1.45813 0.02137  -0.16562 -0.13471 162 ARG A NH1 
2305 N NH2 . ARG A 162 ? 1.84459 1.77856 1.51875 0.03855  -0.15724 -0.15157 162 ARG A NH2 
2319 N N   . GLY A 163 ? 1.24397 1.24480 0.92637 0.04654  -0.14317 -0.01818 163 GLY A N   
2320 C CA  . GLY A 163 ? 1.40194 1.41296 1.05934 0.05640  -0.13949 0.00054  163 GLY A CA  
2321 C C   . GLY A 163 ? 1.23460 1.24817 0.91971 0.05362  -0.12659 0.02391  163 GLY A C   
2322 O O   . GLY A 163 ? 1.23558 1.25041 0.95084 0.04802  -0.13444 0.02923  163 GLY A O   
2326 N N   . GLY A 164 ? 1.19137 1.20573 0.86924 0.05760  -0.10687 0.03765  164 GLY A N   
2327 C CA  . GLY A 164 ? 1.09548 1.11044 0.80216 0.05469  -0.09368 0.05831  164 GLY A CA  
2328 C C   . GLY A 164 ? 1.12086 1.12815 0.84640 0.04874  -0.07551 0.05580  164 GLY A C   
2329 O O   . GLY A 164 ? 1.36076 1.36273 1.07766 0.04709  -0.07232 0.03957  164 GLY A O   
2333 N N   . ASN A 165 ? 1.37725 1.38412 1.13066 0.04575  -0.06400 0.07233  165 ASN A N   
2334 C CA  . ASN A 165 ? 1.14769 1.14875 0.92338 0.03984  -0.04802 0.07176  165 ASN A CA  
2335 C C   . ASN A 165 ? 1.05696 1.05099 0.86441 0.02970  -0.05199 0.05889  165 ASN A C   
2336 O O   . ASN A 165 ? 1.00571 0.99523 0.82694 0.02466  -0.04232 0.05241  165 ASN A O   
2337 C CB  . ASN A 165 ? 1.18297 1.18665 0.97591 0.04146  -0.03441 0.09488  165 ASN A CB  
2338 C CG  . ASN A 165 ? 1.42382 1.43686 1.18768 0.05264  -0.03040 0.11308  165 ASN A CG  
2339 O OD1 . ASN A 165 ? 1.37394 1.39051 1.11324 0.05847  -0.02036 0.11389  165 ASN A OD1 
2340 N ND2 . ASN A 165 ? 1.45622 1.47440 1.22233 0.05662  -0.03791 0.12852  165 ASN A ND2 
2347 N N   . THR A 166 ? 0.75774 0.75215 0.57632 0.02731  -0.06604 0.05529  166 THR A N   
2348 C CA  . THR A 166 ? 0.79490 0.78472 0.64531 0.01912  -0.06801 0.04686  166 THR A CA  
2349 C C   . THR A 166 ? 0.63012 0.61479 0.48197 0.01412  -0.06309 0.03075  166 THR A C   
2350 O O   . THR A 166 ? 0.80529 0.78890 0.63657 0.01554  -0.06764 0.01927  166 THR A O   
2351 C CB  . THR A 166 ? 0.80428 0.79690 0.66143 0.01822  -0.08481 0.04259  166 THR A CB  
2352 O OG1 . THR A 166 ? 0.94253 0.94127 0.79785 0.02372  -0.09077 0.05847  166 THR A OG1 
2353 C CG2 . THR A 166 ? 0.61882 0.60839 0.50985 0.01114  -0.08413 0.03657  166 THR A CG2 
2361 N N   . VAL A 167 ? 0.58170 0.56320 0.45858 0.00873  -0.05431 0.02963  167 VAL A N   
2362 C CA  . VAL A 167 ? 0.56954 0.54769 0.45276 0.00387  -0.05056 0.01615  167 VAL A CA  
2363 C C   . VAL A 167 ? 0.53832 0.51593 0.44922 -0.00122 -0.05301 0.01228  167 VAL A C   
2364 O O   . VAL A 167 ? 0.54794 0.52616 0.47656 -0.00130 -0.05201 0.02030  167 VAL A O   
2365 C CB  . VAL A 167 ? 0.53285 0.51003 0.41676 0.00345  -0.03658 0.01826  167 VAL A CB  
2366 C CG1 . VAL A 167 ? 0.63140 0.61002 0.48675 0.00935  -0.03262 0.02012  167 VAL A CG1 
2367 C CG2 . VAL A 167 ? 0.59271 0.57018 0.49721 0.00257  -0.02924 0.03051  167 VAL A CG2 
2377 N N   . ILE A 168 ? 0.64680 0.62355 0.56225 -0.00468 -0.05568 0.00073  168 ILE A N   
2378 C CA  . ILE A 168 ? 0.52639 0.50438 0.46592 -0.00833 -0.05606 -0.00261 168 ILE A CA  
2379 C C   . ILE A 168 ? 0.54966 0.52699 0.49597 -0.01104 -0.04643 -0.00836 168 ILE A C   
2380 O O   . ILE A 168 ? 0.48906 0.46521 0.42374 -0.01136 -0.04367 -0.01365 168 ILE A O   
2381 C CB  . ILE A 168 ? 0.56581 0.54558 0.50978 -0.00989 -0.06650 -0.00864 168 ILE A CB  
2382 C CG1 . ILE A 168 ? 0.59821 0.58017 0.53601 -0.00713 -0.07851 -0.00366 168 ILE A CG1 
2383 C CG2 . ILE A 168 ? 0.54466 0.52759 0.51337 -0.01247 -0.06451 -0.01023 168 ILE A CG2 
2384 C CD1 . ILE A 168 ? 0.84333 0.82742 0.78937 -0.00430 -0.07777 0.00861  168 ILE A CD1 
2396 N N   . CYS A 169 ? 0.58972 0.56819 0.55509 -0.01238 -0.04191 -0.00797 169 CYS A N   
2397 C CA  . CYS A 169 ? 0.48380 0.46328 0.45602 -0.01440 -0.03439 -0.01395 169 CYS A CA  
2398 C C   . CYS A 169 ? 0.52776 0.51118 0.51368 -0.01521 -0.03497 -0.01930 169 CYS A C   
2399 O O   . CYS A 169 ? 0.60885 0.59313 0.60968 -0.01428 -0.03441 -0.01827 169 CYS A O   
2400 C CB  . CYS A 169 ? 0.46749 0.44509 0.44936 -0.01455 -0.02821 -0.01029 169 CYS A CB  
2401 S SG  . CYS A 169 ? 0.51774 0.49763 0.51362 -0.01681 -0.02227 -0.01952 169 CYS A SG  
2407 N N   . ALA A 170 ? 0.49156 0.47766 0.47339 -0.01624 -0.03491 -0.02431 170 ALA A N   
2408 C CA  . ALA A 170 ? 0.43365 0.42531 0.42734 -0.01618 -0.03421 -0.02698 170 ALA A CA  
2409 C C   . ALA A 170 ? 0.42253 0.41775 0.42350 -0.01517 -0.02755 -0.03121 170 ALA A C   
2410 O O   . ALA A 170 ? 0.45181 0.44673 0.44720 -0.01583 -0.02405 -0.03439 170 ALA A O   
2411 C CB  . ALA A 170 ? 0.51173 0.50518 0.50078 -0.01730 -0.03493 -0.02916 170 ALA A CB  
2417 N N   . THR A 171 ? 0.49143 0.49067 0.50541 -0.01313 -0.02611 -0.03201 171 THR A N   
2418 C CA  . THR A 171 ? 0.54702 0.54888 0.56702 -0.01105 -0.02075 -0.03836 171 THR A CA  
2419 C C   . THR A 171 ? 0.60353 0.61480 0.62754 -0.00787 -0.01654 -0.04122 171 THR A C   
2420 O O   . THR A 171 ? 0.55952 0.57505 0.58766 -0.00761 -0.01732 -0.03614 171 THR A O   
2421 C CB  . THR A 171 ? 0.50742 0.50432 0.54056 -0.00962 -0.02098 -0.03770 171 THR A CB  
2422 O OG1 . THR A 171 ? 0.56269 0.56277 0.60772 -0.00709 -0.02198 -0.03412 171 THR A OG1 
2423 C CG2 . THR A 171 ? 0.45753 0.44662 0.48768 -0.01180 -0.02436 -0.03094 171 THR A CG2 
2431 N N   . GLN A 172 ? 0.66602 0.68098 0.68952 -0.00520 -0.01216 -0.04946 172 GLN A N   
2432 C CA  . GLN A 172 ? 0.66109 0.68599 0.68659 0.00012  -0.00650 -0.05381 172 GLN A CA  
2433 C C   . GLN A 172 ? 0.66605 0.69999 0.67928 0.00096  -0.00407 -0.05323 172 GLN A C   
2434 O O   . GLN A 172 ? 0.77022 0.81109 0.77564 0.00438  -0.00128 -0.06061 172 GLN A O   
2435 C CB  . GLN A 172 ? 0.74004 0.76857 0.77890 0.00277  -0.00467 -0.04757 172 GLN A CB  
2436 C CG  . GLN A 172 ? 0.94875 0.97596 1.00061 0.00736  -0.00166 -0.05281 172 GLN A CG  
2437 C CD  . GLN A 172 ? 1.16607 1.20380 1.21585 0.01477  0.00658  -0.06047 172 GLN A CD  
2438 O OE1 . GLN A 172 ? 1.08693 1.13556 1.13825 0.01828  0.01197  -0.05474 172 GLN A OE1 
2439 N NE2 . GLN A 172 ? 1.15436 1.18923 1.20147 0.01757  0.00766  -0.07350 172 GLN A NE2 
2448 C C01 . AG7 B .   ? 0.61490 0.57279 0.48804 -0.00704 -0.11126 -0.06498 201 AG7 A C01 
2449 C C02 . AG7 B .   ? 0.67992 0.63457 0.58072 -0.01299 -0.11095 -0.06980 201 AG7 A C02 
2450 O O03 . AG7 B .   ? 0.59694 0.55631 0.45864 -0.00411 -0.09882 -0.05778 201 AG7 A O03 
2451 C C04 . AG7 B .   ? 0.55278 0.50724 0.46372 -0.01455 -0.09505 -0.06529 201 AG7 A C04 
2452 C C05 . AG7 B .   ? 0.58392 0.53742 0.52379 -0.01978 -0.09640 -0.06708 201 AG7 A C05 
2453 C C06 . AG7 B .   ? 0.61754 0.57931 0.58297 -0.02346 -0.09729 -0.05810 201 AG7 A C06 
2454 C C07 . AG7 B .   ? 0.54727 0.51581 0.51798 -0.02311 -0.08642 -0.04863 201 AG7 A C07 
2455 C C08 . AG7 B .   ? 0.64719 0.62341 0.64094 -0.02519 -0.08639 -0.04159 201 AG7 A C08 
2456 C C09 . AG7 B .   ? 0.62408 0.60232 0.63850 -0.02824 -0.09713 -0.04218 201 AG7 A C09 
2457 C C10 . AG7 B .   ? 0.68662 0.65847 0.69923 -0.02976 -0.10937 -0.05114 201 AG7 A C10 
2458 C C11 . AG7 B .   ? 0.72906 0.69221 0.71589 -0.02711 -0.10942 -0.05988 201 AG7 A C11 
2459 N N12 . AG7 B .   ? 0.59705 0.54825 0.48033 -0.00839 -0.07416 -0.06470 201 AG7 A N12 
2460 C C13 . AG7 B .   ? 0.64270 0.59062 0.50812 -0.00376 -0.06500 -0.06787 201 AG7 A C13 
2461 C C14 . AG7 B .   ? 0.56144 0.51399 0.40805 0.00061  -0.05887 -0.05965 201 AG7 A C14 
2462 C C15 . AG7 B .   ? 0.56313 0.51691 0.38841 0.00498  -0.06780 -0.05912 201 AG7 A C15 
2463 C C16 . AG7 B .   ? 0.55985 0.51877 0.36904 0.00999  -0.05778 -0.04772 201 AG7 A C16 
2464 N N17 . AG7 B .   ? 0.66254 0.62092 0.44281 0.01720  -0.06096 -0.05165 201 AG7 A N17 
2465 O O18 . AG7 B .   ? 0.57815 0.54117 0.39909 0.00818  -0.04836 -0.03701 201 AG7 A O18 
2466 C C19 . AG7 B .   ? 0.66576 0.61481 0.54731 -0.00602 -0.05435 -0.06524 201 AG7 A C19 
2467 C C20 . AG7 B .   ? 0.62831 0.57390 0.53095 -0.00986 -0.05872 -0.06974 201 AG7 A C20 
2468 C C21 . AG7 B .   ? 0.77795 0.71357 0.67562 -0.00805 -0.06594 -0.08226 201 AG7 A C21 
2469 O O22 . AG7 B .   ? 0.97853 0.91193 0.89939 -0.01268 -0.07301 -0.08403 201 AG7 A O22 
2470 O O23 . AG7 B .   ? 0.71953 0.64973 0.59708 -0.00287 -0.06516 -0.09010 201 AG7 A O23 
2471 C C47 . AG7 B .   ? 0.62450 0.57302 0.51262 -0.01001 -0.08796 -0.07145 201 AG7 A C47 
2472 O O48 . AG7 B .   ? 0.73520 0.67710 0.61104 -0.00762 -0.09505 -0.08277 201 AG7 A O48 
2473 C C50 . AG7 B .   ? 1.28588 1.21088 1.20928 -0.01342 -0.08638 -0.09601 201 AG7 A C50 
2474 C C53 . AG7 B .   ? 1.27998 1.21006 1.23103 -0.01975 -0.09369 -0.09000 201 AG7 A C53 
2475 C C57 . AG7 B .   ? 0.80239 0.76281 0.66264 -0.00431 -0.12843 -0.06840 201 AG7 A C57 
2476 N N58 . AG7 B .   ? 0.73370 0.70220 0.59926 -0.00355 -0.12609 -0.05340 201 AG7 A N58 
2477 C C59 . AG7 B .   ? 0.80130 0.77592 0.68891 -0.00649 -0.13537 -0.04772 201 AG7 A C59 
2478 O O60 . AG7 B .   ? 0.83429 0.80955 0.74140 -0.01067 -0.14727 -0.05379 201 AG7 A O60 
2479 C C78 . AG7 B .   ? 0.79960 0.75591 0.62377 0.00283  -0.13192 -0.07848 201 AG7 A C78 
2480 C C81 . AG7 B .   ? 0.89139 0.85535 0.69616 0.00805  -0.14212 -0.07235 201 AG7 A C81 
2481 F F1  . AG7 B .   ? 0.65186 0.63866 0.69052 -0.02959 -0.09612 -0.03464 201 AG7 A F1  
2482 C C82 . AG7 B .   ? 0.90379 0.85682 0.70794 0.00764  -0.11494 -0.07766 201 AG7 A C82 
2483 C C83 . AG7 B .   ? 0.64693 0.59925 0.41855 0.01812  -0.07406 -0.06758 201 AG7 A C83 
2484 C C84 . AG7 B .   ? 0.61414 0.56198 0.41689 0.01002  -0.07590 -0.07286 201 AG7 A C84 
2485 C C1  . AG7 B .   ? 0.87622 0.85722 0.76857 -0.00444 -0.12952 -0.03214 201 AG7 A C1  
2486 C C2  . AG7 B .   ? 1.03191 1.01906 0.95293 -0.00711 -0.13242 -0.02382 201 AG7 A C2  
2487 C C3  . AG7 B .   ? 1.02542 1.01509 0.94293 -0.00357 -0.12445 -0.01125 201 AG7 A C3  
2488 O O4  . AG7 B .   ? 0.97121 0.95740 0.86120 0.00045  -0.11696 -0.01082 201 AG7 A O4  
2489 N N5  . AG7 B .   ? 0.89396 0.87525 0.76772 0.00027  -0.11968 -0.02388 201 AG7 A N5  
2490 C C4  . AG7 B .   ? 0.74041 0.73521 0.68024 -0.00308 -0.12217 0.00122  201 AG7 A C4  
# 
