data_9DAJ
# 
_entry.id   9DAJ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DAJ         pdb_00009daj 10.2210/pdb9daj/pdb 
WWPDB D_1000287715 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-19 ? 
2 'Structure model' 1 1 2025-03-12 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_citation.journal_volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DAJ 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              vprasad@bcm.edu 
_pdbx_contact_author.name_first         B.V.V 
_pdbx_contact_author.name_last          Prasad 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1172-2071 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Pham, S.H.'     1 0000-0001-6642-8796 
'Neetu, N.'      2 ?                   
'Sankaran, B.'   3 0000-0002-3266-8131 
'Prasad, B.V.V.' 4 0000-0002-1172-2071 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Virol. 
_citation.journal_id_ASTM           JOVIAM 
_citation.journal_id_CSD            0825 
_citation.journal_id_ISSN           1098-5514 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            99 
_citation.language                  ? 
_citation.page_first                e0175724 
_citation.page_last                 e0175724 
_citation.title                     
'Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1128/jvi.01757-24 
_citation.pdbx_database_id_PubMed   39873493 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Pham, S.'       1  ?                   
primary 'Zhao, B.'       2  ?                   
primary 'Neetu, N.'      3  ?                   
primary 'Sankaran, B.'   4  ?                   
primary 'Patil, K.'      5  ?                   
primary 'Ramani, S.'     6  0000-0001-5631-8534 
primary 'Song, Y.'       7  ?                   
primary 'Estes, M.K.'    8  0000-0002-4813-4249 
primary 'Palzkill, T.'   9  ?                   
primary 'Prasad, B.V.V.' 10 0000-0002-1172-2071 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Peptidase C37' 19330.301 1  ? ? ? ? 
2 non-polymer syn 'IODIDE ION' 126.904   8  ? ? ? ? 
3 non-polymer syn 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
600.678   1  ? ? ? ? 
4 water       nat water 18.015    23 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQSAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEATLE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQSAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEATLE
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'IODIDE ION' IOD 
3 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
AG7 
4 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   PRO n 
1 3   PRO n 
1 4   SER n 
1 5   ILE n 
1 6   TRP n 
1 7   SER n 
1 8   ARG n 
1 9   ILE n 
1 10  VAL n 
1 11  ASN n 
1 12  PHE n 
1 13  GLY n 
1 14  SER n 
1 15  GLY n 
1 16  TRP n 
1 17  GLY n 
1 18  PHE n 
1 19  TRP n 
1 20  VAL n 
1 21  SER n 
1 22  PRO n 
1 23  SER n 
1 24  LEU n 
1 25  PHE n 
1 26  ILE n 
1 27  THR n 
1 28  SER n 
1 29  THR n 
1 30  HIS n 
1 31  VAL n 
1 32  ILE n 
1 33  PRO n 
1 34  GLN n 
1 35  SER n 
1 36  ALA n 
1 37  LYS n 
1 38  GLU n 
1 39  PHE n 
1 40  PHE n 
1 41  GLY n 
1 42  VAL n 
1 43  PRO n 
1 44  ILE n 
1 45  LYS n 
1 46  GLN n 
1 47  ILE n 
1 48  GLN n 
1 49  ILE n 
1 50  HIS n 
1 51  LYS n 
1 52  SER n 
1 53  GLY n 
1 54  GLU n 
1 55  PHE n 
1 56  CYS n 
1 57  ARG n 
1 58  LEU n 
1 59  ARG n 
1 60  PHE n 
1 61  PRO n 
1 62  LYS n 
1 63  PRO n 
1 64  ILE n 
1 65  ARG n 
1 66  THR n 
1 67  ASP n 
1 68  VAL n 
1 69  THR n 
1 70  GLY n 
1 71  MET n 
1 72  ILE n 
1 73  LEU n 
1 74  GLU n 
1 75  GLU n 
1 76  GLY n 
1 77  ALA n 
1 78  PRO n 
1 79  GLU n 
1 80  GLY n 
1 81  THR n 
1 82  VAL n 
1 83  ALA n 
1 84  THR n 
1 85  LEU n 
1 86  LEU n 
1 87  ILE n 
1 88  LYS n 
1 89  ARG n 
1 90  PRO n 
1 91  THR n 
1 92  GLY n 
1 93  GLU n 
1 94  LEU n 
1 95  MET n 
1 96  PRO n 
1 97  LEU n 
1 98  ALA n 
1 99  ALA n 
1 100 ARG n 
1 101 MET n 
1 102 GLY n 
1 103 THR n 
1 104 HIS n 
1 105 ALA n 
1 106 THR n 
1 107 MET n 
1 108 LYS n 
1 109 ILE n 
1 110 GLN n 
1 111 GLY n 
1 112 ARG n 
1 113 THR n 
1 114 VAL n 
1 115 GLY n 
1 116 GLY n 
1 117 GLN n 
1 118 MET n 
1 119 GLY n 
1 120 MET n 
1 121 LEU n 
1 122 LEU n 
1 123 THR n 
1 124 GLY n 
1 125 SER n 
1 126 ASN n 
1 127 ALA n 
1 128 LYS n 
1 129 SER n 
1 130 MET n 
1 131 ASP n 
1 132 LEU n 
1 133 GLY n 
1 134 THR n 
1 135 THR n 
1 136 PRO n 
1 137 GLY n 
1 138 ASP n 
1 139 CYS n 
1 140 GLY n 
1 141 CYS n 
1 142 PRO n 
1 143 TYR n 
1 144 ILE n 
1 145 TYR n 
1 146 LYS n 
1 147 ARG n 
1 148 GLY n 
1 149 ASN n 
1 150 ASP n 
1 151 TYR n 
1 152 VAL n 
1 153 VAL n 
1 154 ILE n 
1 155 GLY n 
1 156 VAL n 
1 157 HIS n 
1 158 THR n 
1 159 ALA n 
1 160 ALA n 
1 161 ALA n 
1 162 ARG n 
1 163 GLY n 
1 164 GLY n 
1 165 ASN n 
1 166 THR n 
1 167 VAL n 
1 168 ILE n 
1 169 CYS n 
1 170 ALA n 
1 171 THR n 
1 172 GLN n 
1 173 GLY n 
1 174 SER n 
1 175 GLU n 
1 176 GLY n 
1 177 GLU n 
1 178 ALA n 
1 179 THR n 
1 180 LEU n 
1 181 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   181 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      Norovirus 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     142786 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli B' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     37762 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
AG7 non-polymer         . 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
'RUPINTRIVIR, bound form' 'C31 H41 F N4 O7' 600.678 
ALA 'L-peptide linking' y ALANINE ?                         'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE ?                         'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                         'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                         'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE ?                         'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                         'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                         'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE ?                         'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE ?                         'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER ?                         'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                         'C6 H13 N O2'     131.173 
IOD non-polymer         . 'IODIDE ION' ?                         'I -1'            126.904 
LEU 'L-peptide linking' y LEUCINE ?                         'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE ?                         'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE ?                         'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                         'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE ?                         'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE ?                         'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE ?                         'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                         'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE ?                         'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE ?                         'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   ?   ?   ?   A . n 
A 1 2   PRO 2   2   ?   ?   ?   A . n 
A 1 3   PRO 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   4   SER SER A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   TRP 6   6   6   TRP TRP A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   ARG 8   8   8   ARG ARG A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  VAL 10  10  10  VAL VAL A . n 
A 1 11  ASN 11  11  11  ASN ASN A . n 
A 1 12  PHE 12  12  12  PHE PHE A . n 
A 1 13  GLY 13  13  13  GLY GLY A . n 
A 1 14  SER 14  14  14  SER SER A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  TRP 16  16  16  TRP TRP A . n 
A 1 17  GLY 17  17  17  GLY GLY A . n 
A 1 18  PHE 18  18  18  PHE PHE A . n 
A 1 19  TRP 19  19  19  TRP TRP A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  PRO 22  22  22  PRO PRO A . n 
A 1 23  SER 23  23  23  SER SER A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  ILE 26  26  26  ILE ILE A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  SER 28  28  28  SER SER A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  HIS 30  30  30  HIS HIS A . n 
A 1 31  VAL 31  31  31  VAL VAL A . n 
A 1 32  ILE 32  32  32  ILE ILE A . n 
A 1 33  PRO 33  33  33  PRO PRO A . n 
A 1 34  GLN 34  34  34  GLN GLN A . n 
A 1 35  SER 35  35  35  SER SER A . n 
A 1 36  ALA 36  36  36  ALA ALA A . n 
A 1 37  LYS 37  37  37  LYS LYS A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  PHE 39  39  39  PHE PHE A . n 
A 1 40  PHE 40  40  40  PHE PHE A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  PRO 43  43  43  PRO PRO A . n 
A 1 44  ILE 44  44  44  ILE ILE A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  ILE 47  47  47  ILE ILE A . n 
A 1 48  GLN 48  48  48  GLN GLN A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  HIS 50  50  50  HIS HIS A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  PHE 55  55  55  PHE PHE A . n 
A 1 56  CYS 56  56  56  CYS CYS A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  PHE 60  60  60  PHE PHE A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  ILE 64  64  64  ILE ILE A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  THR 69  69  69  THR THR A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  MET 71  71  71  MET MET A . n 
A 1 72  ILE 72  72  72  ILE ILE A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLU 74  74  74  GLU GLU A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  GLY 76  76  76  GLY GLY A . n 
A 1 77  ALA 77  77  77  ALA ALA A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  GLU 79  79  79  GLU GLU A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  THR 81  81  81  THR THR A . n 
A 1 82  VAL 82  82  82  VAL VAL A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  LEU 85  85  85  LEU LEU A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  ILE 87  87  87  ILE ILE A . n 
A 1 88  LYS 88  88  88  LYS LYS A . n 
A 1 89  ARG 89  89  89  ARG ARG A . n 
A 1 90  PRO 90  90  90  PRO PRO A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  GLU 93  93  93  GLU GLU A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  MET 95  95  95  MET MET A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 ARG 100 100 100 ARG ARG A . n 
A 1 101 MET 101 101 101 MET MET A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 HIS 104 104 104 HIS HIS A . n 
A 1 105 ALA 105 105 105 ALA ALA A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 MET 107 107 107 MET MET A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 ILE 109 109 109 ILE ILE A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 GLY 111 111 111 GLY GLY A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 GLN 117 117 117 GLN GLN A . n 
A 1 118 MET 118 118 118 MET MET A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 MET 120 120 120 MET MET A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 THR 123 123 ?   ?   ?   A . n 
A 1 124 GLY 124 124 ?   ?   ?   A . n 
A 1 125 SER 125 125 ?   ?   ?   A . n 
A 1 126 ASN 126 126 ?   ?   ?   A . n 
A 1 127 ALA 127 127 ?   ?   ?   A . n 
A 1 128 LYS 128 128 ?   ?   ?   A . n 
A 1 129 SER 129 129 ?   ?   ?   A . n 
A 1 130 MET 130 130 ?   ?   ?   A . n 
A 1 131 ASP 131 131 ?   ?   ?   A . n 
A 1 132 LEU 132 132 ?   ?   ?   A . n 
A 1 133 GLY 133 133 133 GLY GLY A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 PRO 136 136 136 PRO PRO A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 CYS 139 139 139 CYS CYS A . n 
A 1 140 GLY 140 140 140 GLY GLY A . n 
A 1 141 CYS 141 141 141 CYS CYS A . n 
A 1 142 PRO 142 142 142 PRO PRO A . n 
A 1 143 TYR 143 143 143 TYR TYR A . n 
A 1 144 ILE 144 144 144 ILE ILE A . n 
A 1 145 TYR 145 145 145 TYR TYR A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 ARG 147 147 147 ARG ARG A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 ASN 149 149 149 ASN ASN A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 TYR 151 151 151 TYR TYR A . n 
A 1 152 VAL 152 152 152 VAL VAL A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 ILE 154 154 154 ILE ILE A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 HIS 157 157 157 HIS HIS A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 ALA 159 159 159 ALA ALA A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 ARG 162 162 162 ARG ARG A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 ASN 165 165 165 ASN ASN A . n 
A 1 166 THR 166 166 166 THR THR A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 CYS 169 169 169 CYS CYS A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 THR 171 171 171 THR THR A . n 
A 1 172 GLN 172 172 172 GLN GLN A . n 
A 1 173 GLY 173 173 ?   ?   ?   A . n 
A 1 174 SER 174 174 ?   ?   ?   A . n 
A 1 175 GLU 175 175 ?   ?   ?   A . n 
A 1 176 GLY 176 176 ?   ?   ?   A . n 
A 1 177 GLU 177 177 ?   ?   ?   A . n 
A 1 178 ALA 178 178 ?   ?   ?   A . n 
A 1 179 THR 179 179 ?   ?   ?   A . n 
A 1 180 LEU 180 180 ?   ?   ?   A . n 
A 1 181 GLU 181 181 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        AG7 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   AG7 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 IOD 1  201 1   IOD IOD A . 
C 2 IOD 1  202 2   IOD IOD A . 
D 2 IOD 1  203 3   IOD IOD A . 
E 2 IOD 1  204 4   IOD IOD A . 
F 2 IOD 1  205 5   IOD IOD A . 
G 2 IOD 1  206 6   IOD IOD A . 
H 2 IOD 1  207 7   IOD IOD A . 
I 2 IOD 1  208 8   IOD IOD A . 
J 3 AG7 1  209 201 AG7 AG7 A . 
K 4 HOH 1  301 26  HOH HOH A . 
K 4 HOH 2  302 8   HOH HOH A . 
K 4 HOH 3  303 24  HOH HOH A . 
K 4 HOH 4  304 1   HOH HOH A . 
K 4 HOH 5  305 10  HOH HOH A . 
K 4 HOH 6  306 17  HOH HOH A . 
K 4 HOH 7  307 16  HOH HOH A . 
K 4 HOH 8  308 11  HOH HOH A . 
K 4 HOH 9  309 2   HOH HOH A . 
K 4 HOH 10 310 29  HOH HOH A . 
K 4 HOH 11 311 14  HOH HOH A . 
K 4 HOH 12 312 19  HOH HOH A . 
K 4 HOH 13 313 22  HOH HOH A . 
K 4 HOH 14 314 20  HOH HOH A . 
K 4 HOH 15 315 21  HOH HOH A . 
K 4 HOH 16 316 25  HOH HOH A . 
K 4 HOH 17 317 6   HOH HOH A . 
K 4 HOH 18 318 18  HOH HOH A . 
K 4 HOH 19 319 5   HOH HOH A . 
K 4 HOH 20 320 12  HOH HOH A . 
K 4 HOH 21 321 13  HOH HOH A . 
K 4 HOH 22 322 4   HOH HOH A . 
K 4 HOH 23 323 15  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.21rc1_5156 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .            2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .            3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .            4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DAJ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     97.722 
_cell.length_a_esd                 ? 
_cell.length_b                     97.722 
_cell.length_b_esd                 ? 
_cell.length_c                     44.620 
_cell.length_c_esd                 ? 
_cell.volume                       369014.230 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DAJ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DAJ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.18 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          61.34 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.3 M Sodium Iodide, 0.1 M Potassium Nitrate:NaOH, 22.5 % (v/v) PurePEGs Cocktail' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-08-30 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97946 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL9-2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97946 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL9-2 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          42.93 
_reflns.entry_id                                       9DAJ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.5 
_reflns.d_resolution_low                               48.96 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     16516 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.53 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.66 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.1238 
_reflns.pdbx_Rpim_I_all                                0.04865 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.93 
_reflns.pdbx_CC_star                                   0.982 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.1122 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.5 
_reflns_shell.d_res_low                                     2.86 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.64 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3074 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               2.6 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.787 
_reflns_shell.pdbx_CC_star                                  0.938 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.98 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               42.98 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9DAJ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.50 
_refine.ls_d_res_low                             48.86 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     8664 
_refine.ls_number_reflns_R_free                  438 
_refine.ls_number_reflns_R_work                  8226 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.53 
_refine.ls_percent_reflns_R_free                 5.06 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2260 
_refine.ls_R_factor_R_free                       0.2705 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2236 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.6783 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3013 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.50 
_refine_hist.d_res_low                        48.86 
_refine_hist.number_atoms_solvent             23 
_refine_hist.number_atoms_total               1277 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1203 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         51 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0031  ? 1276 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.6441  ? 1727 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0486  ? 191  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0066  ? 218  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 18.4873 ? 455  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.50 2.86  . . 135 2678 98.91 . . . . 0.2977 . . . . . . . . . . . 0.3162 
'X-RAY DIFFRACTION' 2.86 3.60  . . 147 2730 99.90 . . . . 0.2400 . . . . . . . . . . . 0.2859 
'X-RAY DIFFRACTION' 3.61 48.86 . . 156 2818 99.77 . . . . 0.1964 . . . . . . . . . . . 0.2506 
# 
_struct.entry_id                     9DAJ 
_struct.title                        'Human norovirus GII.4 Sydney protease in complex with rupintrivir' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DAJ 
_struct_keywords.text            'Viral protease with inhibitor, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 3 ? 
K N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    K4L8Z7_9CALI 
_struct_ref.pdbx_db_accession          K4L8Z7 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQSAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEATLE
;
_struct_ref.pdbx_align_begin           1009 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9DAJ 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 181 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             K4L8Z7 
_struct_ref_seq.db_align_beg                  1009 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1189 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       181 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 SER A 4   ? SER A 7   ? SER A 4   SER A 7   5 ? 4 
HELX_P HELX_P2 AA2 LYS A 45  ? ILE A 47  ? LYS A 45  ILE A 47  5 ? 3 
HELX_P HELX_P3 AA3 THR A 135 ? CYS A 139 ? THR A 135 CYS A 139 5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        none 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            139 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           J 
_struct_conn.ptnr2_label_comp_id           AG7 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C19 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             139 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            AG7 
_struct_conn.ptnr2_auth_seq_id             209 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.769 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      AG7 
_pdbx_modification_feature.label_asym_id                      J 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      139 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       AG7 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        209 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       139 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               C19 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        AG7 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 9   ? PHE A 12  ? ILE A 9   PHE A 12  
AA1 2 GLY A 15  ? TRP A 19  ? GLY A 15  TRP A 19  
AA1 3 LEU A 24  ? SER A 28  ? LEU A 24  SER A 28  
AA1 4 PHE A 55  ? ARG A 59  ? PHE A 55  ARG A 59  
AA1 5 GLN A 48  ? SER A 52  ? GLN A 48  SER A 52  
AA2 1 GLU A 38  ? PHE A 39  ? GLU A 38  PHE A 39  
AA2 2 VAL A 42  ? PRO A 43  ? VAL A 42  PRO A 43  
AA3 1 ILE A 72  ? LEU A 73  ? ILE A 72  LEU A 73  
AA3 2 ASP A 150 ? ALA A 160 ? ASP A 150 ALA A 160 
AA3 3 VAL A 167 ? ALA A 170 ? VAL A 167 ALA A 170 
AA3 4 ARG A 112 ? LEU A 121 ? ARG A 112 LEU A 121 
AA3 5 LEU A 94  ? ILE A 109 ? LEU A 94  ILE A 109 
AA3 6 VAL A 82  ? LYS A 88  ? VAL A 82  LYS A 88  
AA3 7 PRO A 142 ? ARG A 147 ? PRO A 142 ARG A 147 
AA3 8 ASP A 150 ? ALA A 160 ? ASP A 150 ALA A 160 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 12  ? N PHE A 12  O GLY A 15  ? O GLY A 15  
AA1 2 3 N PHE A 18  ? N PHE A 18  O ILE A 26  ? O ILE A 26  
AA1 3 4 N PHE A 25  ? N PHE A 25  O LEU A 58  ? O LEU A 58  
AA1 4 5 O PHE A 55  ? O PHE A 55  N SER A 52  ? N SER A 52  
AA2 1 2 N PHE A 39  ? N PHE A 39  O VAL A 42  ? O VAL A 42  
AA3 1 2 N ILE A 72  ? N ILE A 72  O VAL A 153 ? O VAL A 153 
AA3 2 3 N VAL A 156 ? N VAL A 156 O ALA A 170 ? O ALA A 170 
AA3 3 4 O CYS A 169 ? O CYS A 169 N GLN A 117 ? N GLN A 117 
AA3 4 5 O MET A 118 ? O MET A 118 N GLY A 102 ? N GLY A 102 
AA3 5 6 O ALA A 99  ? O ALA A 99  N ALA A 83  ? N ALA A 83  
AA3 6 7 N THR A 84  ? N THR A 84  O ILE A 144 ? O ILE A 144 
AA3 7 8 N ARG A 147 ? N ARG A 147 O ASP A 150 ? O ASP A 150 
# 
_pdbx_entry_details.entry_id                   9DAJ 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   SG 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   CYS 
_pdbx_validate_close_contact.auth_seq_id_1    139 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   H191 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   AG7 
_pdbx_validate_close_contact.auth_seq_id_2    209 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             1.03 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A IOD 203 ? D IOD . 
2 1 A HOH 316 ? K HOH . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
_pdbx_refine_tls.id               1 
_pdbx_refine_tls.pdbx_refine_id   'X-RAY DIFFRACTION' 
_pdbx_refine_tls.details          ? 
_pdbx_refine_tls.method           refined 
_pdbx_refine_tls.origin_x         -31.7907832286 
_pdbx_refine_tls.origin_y         -26.1145197939 
_pdbx_refine_tls.origin_z         2.46362965439 
_pdbx_refine_tls.T[1][1]          0.164235364862 
_pdbx_refine_tls.T[1][1]_esd      ? 
_pdbx_refine_tls.T[1][2]          0.000498710234582 
_pdbx_refine_tls.T[1][2]_esd      ? 
_pdbx_refine_tls.T[1][3]          0.0430827434365 
_pdbx_refine_tls.T[1][3]_esd      ? 
_pdbx_refine_tls.T[2][2]          0.202407187944 
_pdbx_refine_tls.T[2][2]_esd      ? 
_pdbx_refine_tls.T[2][3]          -0.0324334990257 
_pdbx_refine_tls.T[2][3]_esd      ? 
_pdbx_refine_tls.T[3][3]          0.189236248536 
_pdbx_refine_tls.T[3][3]_esd      ? 
_pdbx_refine_tls.L[1][1]          4.16870522445 
_pdbx_refine_tls.L[1][1]_esd      ? 
_pdbx_refine_tls.L[1][2]          -0.635673241436 
_pdbx_refine_tls.L[1][2]_esd      ? 
_pdbx_refine_tls.L[1][3]          0.980891947303 
_pdbx_refine_tls.L[1][3]_esd      ? 
_pdbx_refine_tls.L[2][2]          2.48197885163 
_pdbx_refine_tls.L[2][2]_esd      ? 
_pdbx_refine_tls.L[2][3]          -0.684798989997 
_pdbx_refine_tls.L[2][3]_esd      ? 
_pdbx_refine_tls.L[3][3]          2.77006987931 
_pdbx_refine_tls.L[3][3]_esd      ? 
_pdbx_refine_tls.S[1][1]          0.0137110141604 
_pdbx_refine_tls.S[1][1]_esd      ? 
_pdbx_refine_tls.S[1][2]          -0.201829723919 
_pdbx_refine_tls.S[1][2]_esd      ? 
_pdbx_refine_tls.S[1][3]          0.126531121106 
_pdbx_refine_tls.S[1][3]_esd      ? 
_pdbx_refine_tls.S[2][1]          0.0495262334219 
_pdbx_refine_tls.S[2][1]_esd      ? 
_pdbx_refine_tls.S[2][2]          -0.0127572887611 
_pdbx_refine_tls.S[2][2]_esd      ? 
_pdbx_refine_tls.S[2][3]          -0.164296130685 
_pdbx_refine_tls.S[2][3]_esd      ? 
_pdbx_refine_tls.S[3][1]          -0.0293810651942 
_pdbx_refine_tls.S[3][1]_esd      ? 
_pdbx_refine_tls.S[3][2]          0.0334049528638 
_pdbx_refine_tls.S[3][2]_esd      ? 
_pdbx_refine_tls.S[3][3]          -0.0192177947811 
_pdbx_refine_tls.S[3][3]_esd      ? 
# 
_pdbx_refine_tls_group.id                  1 
_pdbx_refine_tls_group.pdbx_refine_id      'X-RAY DIFFRACTION' 
_pdbx_refine_tls_group.refine_tls_id       1 
_pdbx_refine_tls_group.beg_label_asym_id   A 
_pdbx_refine_tls_group.beg_label_seq_id    1 
_pdbx_refine_tls_group.beg_auth_asym_id    A 
_pdbx_refine_tls_group.beg_auth_seq_id     4 
_pdbx_refine_tls_group.beg_PDB_ins_code    ? 
_pdbx_refine_tls_group.end_label_asym_id   K 
_pdbx_refine_tls_group.end_label_seq_id    ? 
_pdbx_refine_tls_group.end_auth_asym_id    B 
_pdbx_refine_tls_group.end_auth_seq_id     201 
_pdbx_refine_tls_group.end_PDB_ins_code    ? 
_pdbx_refine_tls_group.selection           ? 
_pdbx_refine_tls_group.selection_details   all 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       323 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.08 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ALA 1   ? A ALA 1   
2  1 Y 1 A PRO 2   ? A PRO 2   
3  1 Y 1 A PRO 3   ? A PRO 3   
4  1 Y 1 A THR 123 ? A THR 123 
5  1 Y 1 A GLY 124 ? A GLY 124 
6  1 Y 1 A SER 125 ? A SER 125 
7  1 Y 1 A ASN 126 ? A ASN 126 
8  1 Y 1 A ALA 127 ? A ALA 127 
9  1 Y 1 A LYS 128 ? A LYS 128 
10 1 Y 1 A SER 129 ? A SER 129 
11 1 Y 1 A MET 130 ? A MET 130 
12 1 Y 1 A ASP 131 ? A ASP 131 
13 1 Y 1 A LEU 132 ? A LEU 132 
14 1 Y 1 A GLY 173 ? A GLY 173 
15 1 Y 1 A SER 174 ? A SER 174 
16 1 Y 1 A GLU 175 ? A GLU 175 
17 1 Y 1 A GLY 176 ? A GLY 176 
18 1 Y 1 A GLU 177 ? A GLU 177 
19 1 Y 1 A ALA 178 ? A ALA 178 
20 1 Y 1 A THR 179 ? A THR 179 
21 1 Y 1 A LEU 180 ? A LEU 180 
22 1 Y 1 A GLU 181 ? A GLU 181 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
AG7 C01  C N N 1   
AG7 C02  C N N 2   
AG7 O03  O N N 3   
AG7 C04  C N R 4   
AG7 C05  C N N 5   
AG7 C06  C Y N 6   
AG7 C07  C Y N 7   
AG7 C08  C Y N 8   
AG7 C09  C Y N 9   
AG7 C10  C Y N 10  
AG7 C11  C Y N 11  
AG7 N12  N N N 12  
AG7 C13  C N R 13  
AG7 C14  C N N 14  
AG7 C15  C N S 15  
AG7 C16  C N N 16  
AG7 N17  N N N 17  
AG7 O18  O N N 18  
AG7 C19  C N N 19  
AG7 C20  C N N 20  
AG7 C21  C N N 21  
AG7 O22  O N N 22  
AG7 O23  O N N 23  
AG7 C47  C N N 24  
AG7 O48  O N N 25  
AG7 C50  C N N 26  
AG7 C53  C N N 27  
AG7 C57  C N S 28  
AG7 N58  N N N 29  
AG7 C59  C N N 30  
AG7 O60  O N N 31  
AG7 C78  C N N 32  
AG7 C81  C N N 33  
AG7 F1   F N N 34  
AG7 C82  C N N 35  
AG7 C83  C N N 36  
AG7 C84  C N N 37  
AG7 C1   C Y N 38  
AG7 C2   C Y N 39  
AG7 C3   C Y N 40  
AG7 O4   O Y N 41  
AG7 N5   N Y N 42  
AG7 C4   C N N 43  
AG7 H2   H N N 44  
AG7 H3   H N N 45  
AG7 H27  H N N 46  
AG7 H28  H N N 47  
AG7 H29  H N N 48  
AG7 H30  H N N 49  
AG7 H31  H N N 50  
AG7 H33  H N N 51  
AG7 H34  H N N 52  
AG7 H49  H N N 53  
AG7 H91  H N N 54  
AG7 H35  H N N 55  
AG7 H36  H N N 56  
AG7 H94  H N N 57  
AG7 H39  H N N 58  
AG7 H191 H N N 59  
AG7 H192 H N N 60  
AG7 H41  H N N 61  
AG7 H42  H N N 62  
AG7 H51  H N N 63  
AG7 H52  H N N 64  
AG7 H53  H N N 65  
AG7 H54  H N N 66  
AG7 H56  H N N 67  
AG7 H77  H N N 68  
AG7 H61  H N N 69  
AG7 H79  H N N 70  
AG7 H82  H N N 71  
AG7 H84  H N N 72  
AG7 H85  H N N 73  
AG7 H86  H N N 74  
AG7 H87  H N N 75  
AG7 H88  H N N 76  
AG7 H89  H N N 77  
AG7 H90  H N N 78  
AG7 H92  H N N 79  
AG7 H93  H N N 80  
AG7 H8   H N N 81  
AG7 H5   H N N 82  
AG7 H6   H N N 83  
AG7 H7   H N N 84  
ALA N    N N N 85  
ALA CA   C N S 86  
ALA C    C N N 87  
ALA O    O N N 88  
ALA CB   C N N 89  
ALA OXT  O N N 90  
ALA H    H N N 91  
ALA H2   H N N 92  
ALA HA   H N N 93  
ALA HB1  H N N 94  
ALA HB2  H N N 95  
ALA HB3  H N N 96  
ALA HXT  H N N 97  
ARG N    N N N 98  
ARG CA   C N S 99  
ARG C    C N N 100 
ARG O    O N N 101 
ARG CB   C N N 102 
ARG CG   C N N 103 
ARG CD   C N N 104 
ARG NE   N N N 105 
ARG CZ   C N N 106 
ARG NH1  N N N 107 
ARG NH2  N N N 108 
ARG OXT  O N N 109 
ARG H    H N N 110 
ARG H2   H N N 111 
ARG HA   H N N 112 
ARG HB2  H N N 113 
ARG HB3  H N N 114 
ARG HG2  H N N 115 
ARG HG3  H N N 116 
ARG HD2  H N N 117 
ARG HD3  H N N 118 
ARG HE   H N N 119 
ARG HH11 H N N 120 
ARG HH12 H N N 121 
ARG HH21 H N N 122 
ARG HH22 H N N 123 
ARG HXT  H N N 124 
ASN N    N N N 125 
ASN CA   C N S 126 
ASN C    C N N 127 
ASN O    O N N 128 
ASN CB   C N N 129 
ASN CG   C N N 130 
ASN OD1  O N N 131 
ASN ND2  N N N 132 
ASN OXT  O N N 133 
ASN H    H N N 134 
ASN H2   H N N 135 
ASN HA   H N N 136 
ASN HB2  H N N 137 
ASN HB3  H N N 138 
ASN HD21 H N N 139 
ASN HD22 H N N 140 
ASN HXT  H N N 141 
ASP N    N N N 142 
ASP CA   C N S 143 
ASP C    C N N 144 
ASP O    O N N 145 
ASP CB   C N N 146 
ASP CG   C N N 147 
ASP OD1  O N N 148 
ASP OD2  O N N 149 
ASP OXT  O N N 150 
ASP H    H N N 151 
ASP H2   H N N 152 
ASP HA   H N N 153 
ASP HB2  H N N 154 
ASP HB3  H N N 155 
ASP HD2  H N N 156 
ASP HXT  H N N 157 
CYS N    N N N 158 
CYS CA   C N R 159 
CYS C    C N N 160 
CYS O    O N N 161 
CYS CB   C N N 162 
CYS SG   S N N 163 
CYS OXT  O N N 164 
CYS H    H N N 165 
CYS H2   H N N 166 
CYS HA   H N N 167 
CYS HB2  H N N 168 
CYS HB3  H N N 169 
CYS HG   H N N 170 
CYS HXT  H N N 171 
GLN N    N N N 172 
GLN CA   C N S 173 
GLN C    C N N 174 
GLN O    O N N 175 
GLN CB   C N N 176 
GLN CG   C N N 177 
GLN CD   C N N 178 
GLN OE1  O N N 179 
GLN NE2  N N N 180 
GLN OXT  O N N 181 
GLN H    H N N 182 
GLN H2   H N N 183 
GLN HA   H N N 184 
GLN HB2  H N N 185 
GLN HB3  H N N 186 
GLN HG2  H N N 187 
GLN HG3  H N N 188 
GLN HE21 H N N 189 
GLN HE22 H N N 190 
GLN HXT  H N N 191 
GLU N    N N N 192 
GLU CA   C N S 193 
GLU C    C N N 194 
GLU O    O N N 195 
GLU CB   C N N 196 
GLU CG   C N N 197 
GLU CD   C N N 198 
GLU OE1  O N N 199 
GLU OE2  O N N 200 
GLU OXT  O N N 201 
GLU H    H N N 202 
GLU H2   H N N 203 
GLU HA   H N N 204 
GLU HB2  H N N 205 
GLU HB3  H N N 206 
GLU HG2  H N N 207 
GLU HG3  H N N 208 
GLU HE2  H N N 209 
GLU HXT  H N N 210 
GLY N    N N N 211 
GLY CA   C N N 212 
GLY C    C N N 213 
GLY O    O N N 214 
GLY OXT  O N N 215 
GLY H    H N N 216 
GLY H2   H N N 217 
GLY HA2  H N N 218 
GLY HA3  H N N 219 
GLY HXT  H N N 220 
HIS N    N N N 221 
HIS CA   C N S 222 
HIS C    C N N 223 
HIS O    O N N 224 
HIS CB   C N N 225 
HIS CG   C Y N 226 
HIS ND1  N Y N 227 
HIS CD2  C Y N 228 
HIS CE1  C Y N 229 
HIS NE2  N Y N 230 
HIS OXT  O N N 231 
HIS H    H N N 232 
HIS H2   H N N 233 
HIS HA   H N N 234 
HIS HB2  H N N 235 
HIS HB3  H N N 236 
HIS HD1  H N N 237 
HIS HD2  H N N 238 
HIS HE1  H N N 239 
HIS HE2  H N N 240 
HIS HXT  H N N 241 
HOH O    O N N 242 
HOH H1   H N N 243 
HOH H2   H N N 244 
ILE N    N N N 245 
ILE CA   C N S 246 
ILE C    C N N 247 
ILE O    O N N 248 
ILE CB   C N S 249 
ILE CG1  C N N 250 
ILE CG2  C N N 251 
ILE CD1  C N N 252 
ILE OXT  O N N 253 
ILE H    H N N 254 
ILE H2   H N N 255 
ILE HA   H N N 256 
ILE HB   H N N 257 
ILE HG12 H N N 258 
ILE HG13 H N N 259 
ILE HG21 H N N 260 
ILE HG22 H N N 261 
ILE HG23 H N N 262 
ILE HD11 H N N 263 
ILE HD12 H N N 264 
ILE HD13 H N N 265 
ILE HXT  H N N 266 
IOD I    I N N 267 
LEU N    N N N 268 
LEU CA   C N S 269 
LEU C    C N N 270 
LEU O    O N N 271 
LEU CB   C N N 272 
LEU CG   C N N 273 
LEU CD1  C N N 274 
LEU CD2  C N N 275 
LEU OXT  O N N 276 
LEU H    H N N 277 
LEU H2   H N N 278 
LEU HA   H N N 279 
LEU HB2  H N N 280 
LEU HB3  H N N 281 
LEU HG   H N N 282 
LEU HD11 H N N 283 
LEU HD12 H N N 284 
LEU HD13 H N N 285 
LEU HD21 H N N 286 
LEU HD22 H N N 287 
LEU HD23 H N N 288 
LEU HXT  H N N 289 
LYS N    N N N 290 
LYS CA   C N S 291 
LYS C    C N N 292 
LYS O    O N N 293 
LYS CB   C N N 294 
LYS CG   C N N 295 
LYS CD   C N N 296 
LYS CE   C N N 297 
LYS NZ   N N N 298 
LYS OXT  O N N 299 
LYS H    H N N 300 
LYS H2   H N N 301 
LYS HA   H N N 302 
LYS HB2  H N N 303 
LYS HB3  H N N 304 
LYS HG2  H N N 305 
LYS HG3  H N N 306 
LYS HD2  H N N 307 
LYS HD3  H N N 308 
LYS HE2  H N N 309 
LYS HE3  H N N 310 
LYS HZ1  H N N 311 
LYS HZ2  H N N 312 
LYS HZ3  H N N 313 
LYS HXT  H N N 314 
MET N    N N N 315 
MET CA   C N S 316 
MET C    C N N 317 
MET O    O N N 318 
MET CB   C N N 319 
MET CG   C N N 320 
MET SD   S N N 321 
MET CE   C N N 322 
MET OXT  O N N 323 
MET H    H N N 324 
MET H2   H N N 325 
MET HA   H N N 326 
MET HB2  H N N 327 
MET HB3  H N N 328 
MET HG2  H N N 329 
MET HG3  H N N 330 
MET HE1  H N N 331 
MET HE2  H N N 332 
MET HE3  H N N 333 
MET HXT  H N N 334 
PHE N    N N N 335 
PHE CA   C N S 336 
PHE C    C N N 337 
PHE O    O N N 338 
PHE CB   C N N 339 
PHE CG   C Y N 340 
PHE CD1  C Y N 341 
PHE CD2  C Y N 342 
PHE CE1  C Y N 343 
PHE CE2  C Y N 344 
PHE CZ   C Y N 345 
PHE OXT  O N N 346 
PHE H    H N N 347 
PHE H2   H N N 348 
PHE HA   H N N 349 
PHE HB2  H N N 350 
PHE HB3  H N N 351 
PHE HD1  H N N 352 
PHE HD2  H N N 353 
PHE HE1  H N N 354 
PHE HE2  H N N 355 
PHE HZ   H N N 356 
PHE HXT  H N N 357 
PRO N    N N N 358 
PRO CA   C N S 359 
PRO C    C N N 360 
PRO O    O N N 361 
PRO CB   C N N 362 
PRO CG   C N N 363 
PRO CD   C N N 364 
PRO OXT  O N N 365 
PRO H    H N N 366 
PRO HA   H N N 367 
PRO HB2  H N N 368 
PRO HB3  H N N 369 
PRO HG2  H N N 370 
PRO HG3  H N N 371 
PRO HD2  H N N 372 
PRO HD3  H N N 373 
PRO HXT  H N N 374 
SER N    N N N 375 
SER CA   C N S 376 
SER C    C N N 377 
SER O    O N N 378 
SER CB   C N N 379 
SER OG   O N N 380 
SER OXT  O N N 381 
SER H    H N N 382 
SER H2   H N N 383 
SER HA   H N N 384 
SER HB2  H N N 385 
SER HB3  H N N 386 
SER HG   H N N 387 
SER HXT  H N N 388 
THR N    N N N 389 
THR CA   C N S 390 
THR C    C N N 391 
THR O    O N N 392 
THR CB   C N R 393 
THR OG1  O N N 394 
THR CG2  C N N 395 
THR OXT  O N N 396 
THR H    H N N 397 
THR H2   H N N 398 
THR HA   H N N 399 
THR HB   H N N 400 
THR HG1  H N N 401 
THR HG21 H N N 402 
THR HG22 H N N 403 
THR HG23 H N N 404 
THR HXT  H N N 405 
TRP N    N N N 406 
TRP CA   C N S 407 
TRP C    C N N 408 
TRP O    O N N 409 
TRP CB   C N N 410 
TRP CG   C Y N 411 
TRP CD1  C Y N 412 
TRP CD2  C Y N 413 
TRP NE1  N Y N 414 
TRP CE2  C Y N 415 
TRP CE3  C Y N 416 
TRP CZ2  C Y N 417 
TRP CZ3  C Y N 418 
TRP CH2  C Y N 419 
TRP OXT  O N N 420 
TRP H    H N N 421 
TRP H2   H N N 422 
TRP HA   H N N 423 
TRP HB2  H N N 424 
TRP HB3  H N N 425 
TRP HD1  H N N 426 
TRP HE1  H N N 427 
TRP HE3  H N N 428 
TRP HZ2  H N N 429 
TRP HZ3  H N N 430 
TRP HH2  H N N 431 
TRP HXT  H N N 432 
TYR N    N N N 433 
TYR CA   C N S 434 
TYR C    C N N 435 
TYR O    O N N 436 
TYR CB   C N N 437 
TYR CG   C Y N 438 
TYR CD1  C Y N 439 
TYR CD2  C Y N 440 
TYR CE1  C Y N 441 
TYR CE2  C Y N 442 
TYR CZ   C Y N 443 
TYR OH   O N N 444 
TYR OXT  O N N 445 
TYR H    H N N 446 
TYR H2   H N N 447 
TYR HA   H N N 448 
TYR HB2  H N N 449 
TYR HB3  H N N 450 
TYR HD1  H N N 451 
TYR HD2  H N N 452 
TYR HE1  H N N 453 
TYR HE2  H N N 454 
TYR HH   H N N 455 
TYR HXT  H N N 456 
VAL N    N N N 457 
VAL CA   C N S 458 
VAL C    C N N 459 
VAL O    O N N 460 
VAL CB   C N N 461 
VAL CG1  C N N 462 
VAL CG2  C N N 463 
VAL OXT  O N N 464 
VAL H    H N N 465 
VAL H2   H N N 466 
VAL HA   H N N 467 
VAL HB   H N N 468 
VAL HG11 H N N 469 
VAL HG12 H N N 470 
VAL HG13 H N N 471 
VAL HG21 H N N 472 
VAL HG22 H N N 473 
VAL HG23 H N N 474 
VAL HXT  H N N 475 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
AG7 C01 C02  sing N N 1   
AG7 C01 O03  doub N N 2   
AG7 C01 C57  sing N N 3   
AG7 C02 C04  sing N N 4   
AG7 C02 H2   sing N N 5   
AG7 C02 H3   sing N N 6   
AG7 C04 C05  sing N N 7   
AG7 C04 C47  sing N N 8   
AG7 C04 H27  sing N N 9   
AG7 C05 C06  sing N N 10  
AG7 C05 H28  sing N N 11  
AG7 C05 H29  sing N N 12  
AG7 C06 C07  doub Y N 13  
AG7 C06 C11  sing Y N 14  
AG7 C07 C08  sing Y N 15  
AG7 C07 H30  sing N N 16  
AG7 C08 C09  doub Y N 17  
AG7 C08 H31  sing N N 18  
AG7 C09 C10  sing Y N 19  
AG7 C09 F1   sing N N 20  
AG7 C10 C11  doub Y N 21  
AG7 C10 H33  sing N N 22  
AG7 C11 H34  sing N N 23  
AG7 N12 C13  sing N N 24  
AG7 N12 C47  sing N N 25  
AG7 N12 H49  sing N N 26  
AG7 C13 C14  sing N N 27  
AG7 C13 C19  sing N N 28  
AG7 C13 H91  sing N N 29  
AG7 C14 C15  sing N N 30  
AG7 C14 H35  sing N N 31  
AG7 C14 H36  sing N N 32  
AG7 C15 C16  sing N N 33  
AG7 C15 C84  sing N N 34  
AG7 C15 H94  sing N N 35  
AG7 C16 N17  sing N N 36  
AG7 C16 O18  doub N N 37  
AG7 N17 C83  sing N N 38  
AG7 N17 H39  sing N N 39  
AG7 C19 C20  sing N N 40  
AG7 C19 H191 sing N N 41  
AG7 C19 H192 sing N N 42  
AG7 C20 C21  sing N N 43  
AG7 C20 H41  sing N N 44  
AG7 C20 H42  sing N N 45  
AG7 C21 O22  sing N N 46  
AG7 C21 O23  doub N N 47  
AG7 O22 C50  sing N N 48  
AG7 C47 O48  doub N N 49  
AG7 C50 C53  sing N N 50  
AG7 C50 H51  sing N N 51  
AG7 C50 H52  sing N N 52  
AG7 C53 H53  sing N N 53  
AG7 C53 H54  sing N N 54  
AG7 C53 H56  sing N N 55  
AG7 C57 N58  sing N N 56  
AG7 C57 C78  sing N N 57  
AG7 C57 H77  sing N N 58  
AG7 N58 C59  sing N N 59  
AG7 N58 H61  sing N N 60  
AG7 C59 O60  doub N N 61  
AG7 C59 C1   sing N N 62  
AG7 C78 C81  sing N N 63  
AG7 C78 C82  sing N N 64  
AG7 C78 H79  sing N N 65  
AG7 C81 H82  sing N N 66  
AG7 C81 H84  sing N N 67  
AG7 C81 H85  sing N N 68  
AG7 C82 H86  sing N N 69  
AG7 C82 H87  sing N N 70  
AG7 C82 H88  sing N N 71  
AG7 C83 C84  sing N N 72  
AG7 C83 H89  sing N N 73  
AG7 C83 H90  sing N N 74  
AG7 C84 H92  sing N N 75  
AG7 C84 H93  sing N N 76  
AG7 C1  C2   sing Y N 77  
AG7 C1  N5   doub Y N 78  
AG7 C2  C3   doub Y N 79  
AG7 C2  H8   sing N N 80  
AG7 C3  O4   sing Y N 81  
AG7 C3  C4   sing N N 82  
AG7 O4  N5   sing Y N 83  
AG7 C4  H5   sing N N 84  
AG7 C4  H6   sing N N 85  
AG7 C4  H7   sing N N 86  
ALA N   CA   sing N N 87  
ALA N   H    sing N N 88  
ALA N   H2   sing N N 89  
ALA CA  C    sing N N 90  
ALA CA  CB   sing N N 91  
ALA CA  HA   sing N N 92  
ALA C   O    doub N N 93  
ALA C   OXT  sing N N 94  
ALA CB  HB1  sing N N 95  
ALA CB  HB2  sing N N 96  
ALA CB  HB3  sing N N 97  
ALA OXT HXT  sing N N 98  
ARG N   CA   sing N N 99  
ARG N   H    sing N N 100 
ARG N   H2   sing N N 101 
ARG CA  C    sing N N 102 
ARG CA  CB   sing N N 103 
ARG CA  HA   sing N N 104 
ARG C   O    doub N N 105 
ARG C   OXT  sing N N 106 
ARG CB  CG   sing N N 107 
ARG CB  HB2  sing N N 108 
ARG CB  HB3  sing N N 109 
ARG CG  CD   sing N N 110 
ARG CG  HG2  sing N N 111 
ARG CG  HG3  sing N N 112 
ARG CD  NE   sing N N 113 
ARG CD  HD2  sing N N 114 
ARG CD  HD3  sing N N 115 
ARG NE  CZ   sing N N 116 
ARG NE  HE   sing N N 117 
ARG CZ  NH1  sing N N 118 
ARG CZ  NH2  doub N N 119 
ARG NH1 HH11 sing N N 120 
ARG NH1 HH12 sing N N 121 
ARG NH2 HH21 sing N N 122 
ARG NH2 HH22 sing N N 123 
ARG OXT HXT  sing N N 124 
ASN N   CA   sing N N 125 
ASN N   H    sing N N 126 
ASN N   H2   sing N N 127 
ASN CA  C    sing N N 128 
ASN CA  CB   sing N N 129 
ASN CA  HA   sing N N 130 
ASN C   O    doub N N 131 
ASN C   OXT  sing N N 132 
ASN CB  CG   sing N N 133 
ASN CB  HB2  sing N N 134 
ASN CB  HB3  sing N N 135 
ASN CG  OD1  doub N N 136 
ASN CG  ND2  sing N N 137 
ASN ND2 HD21 sing N N 138 
ASN ND2 HD22 sing N N 139 
ASN OXT HXT  sing N N 140 
ASP N   CA   sing N N 141 
ASP N   H    sing N N 142 
ASP N   H2   sing N N 143 
ASP CA  C    sing N N 144 
ASP CA  CB   sing N N 145 
ASP CA  HA   sing N N 146 
ASP C   O    doub N N 147 
ASP C   OXT  sing N N 148 
ASP CB  CG   sing N N 149 
ASP CB  HB2  sing N N 150 
ASP CB  HB3  sing N N 151 
ASP CG  OD1  doub N N 152 
ASP CG  OD2  sing N N 153 
ASP OD2 HD2  sing N N 154 
ASP OXT HXT  sing N N 155 
CYS N   CA   sing N N 156 
CYS N   H    sing N N 157 
CYS N   H2   sing N N 158 
CYS CA  C    sing N N 159 
CYS CA  CB   sing N N 160 
CYS CA  HA   sing N N 161 
CYS C   O    doub N N 162 
CYS C   OXT  sing N N 163 
CYS CB  SG   sing N N 164 
CYS CB  HB2  sing N N 165 
CYS CB  HB3  sing N N 166 
CYS SG  HG   sing N N 167 
CYS OXT HXT  sing N N 168 
GLN N   CA   sing N N 169 
GLN N   H    sing N N 170 
GLN N   H2   sing N N 171 
GLN CA  C    sing N N 172 
GLN CA  CB   sing N N 173 
GLN CA  HA   sing N N 174 
GLN C   O    doub N N 175 
GLN C   OXT  sing N N 176 
GLN CB  CG   sing N N 177 
GLN CB  HB2  sing N N 178 
GLN CB  HB3  sing N N 179 
GLN CG  CD   sing N N 180 
GLN CG  HG2  sing N N 181 
GLN CG  HG3  sing N N 182 
GLN CD  OE1  doub N N 183 
GLN CD  NE2  sing N N 184 
GLN NE2 HE21 sing N N 185 
GLN NE2 HE22 sing N N 186 
GLN OXT HXT  sing N N 187 
GLU N   CA   sing N N 188 
GLU N   H    sing N N 189 
GLU N   H2   sing N N 190 
GLU CA  C    sing N N 191 
GLU CA  CB   sing N N 192 
GLU CA  HA   sing N N 193 
GLU C   O    doub N N 194 
GLU C   OXT  sing N N 195 
GLU CB  CG   sing N N 196 
GLU CB  HB2  sing N N 197 
GLU CB  HB3  sing N N 198 
GLU CG  CD   sing N N 199 
GLU CG  HG2  sing N N 200 
GLU CG  HG3  sing N N 201 
GLU CD  OE1  doub N N 202 
GLU CD  OE2  sing N N 203 
GLU OE2 HE2  sing N N 204 
GLU OXT HXT  sing N N 205 
GLY N   CA   sing N N 206 
GLY N   H    sing N N 207 
GLY N   H2   sing N N 208 
GLY CA  C    sing N N 209 
GLY CA  HA2  sing N N 210 
GLY CA  HA3  sing N N 211 
GLY C   O    doub N N 212 
GLY C   OXT  sing N N 213 
GLY OXT HXT  sing N N 214 
HIS N   CA   sing N N 215 
HIS N   H    sing N N 216 
HIS N   H2   sing N N 217 
HIS CA  C    sing N N 218 
HIS CA  CB   sing N N 219 
HIS CA  HA   sing N N 220 
HIS C   O    doub N N 221 
HIS C   OXT  sing N N 222 
HIS CB  CG   sing N N 223 
HIS CB  HB2  sing N N 224 
HIS CB  HB3  sing N N 225 
HIS CG  ND1  sing Y N 226 
HIS CG  CD2  doub Y N 227 
HIS ND1 CE1  doub Y N 228 
HIS ND1 HD1  sing N N 229 
HIS CD2 NE2  sing Y N 230 
HIS CD2 HD2  sing N N 231 
HIS CE1 NE2  sing Y N 232 
HIS CE1 HE1  sing N N 233 
HIS NE2 HE2  sing N N 234 
HIS OXT HXT  sing N N 235 
HOH O   H1   sing N N 236 
HOH O   H2   sing N N 237 
ILE N   CA   sing N N 238 
ILE N   H    sing N N 239 
ILE N   H2   sing N N 240 
ILE CA  C    sing N N 241 
ILE CA  CB   sing N N 242 
ILE CA  HA   sing N N 243 
ILE C   O    doub N N 244 
ILE C   OXT  sing N N 245 
ILE CB  CG1  sing N N 246 
ILE CB  CG2  sing N N 247 
ILE CB  HB   sing N N 248 
ILE CG1 CD1  sing N N 249 
ILE CG1 HG12 sing N N 250 
ILE CG1 HG13 sing N N 251 
ILE CG2 HG21 sing N N 252 
ILE CG2 HG22 sing N N 253 
ILE CG2 HG23 sing N N 254 
ILE CD1 HD11 sing N N 255 
ILE CD1 HD12 sing N N 256 
ILE CD1 HD13 sing N N 257 
ILE OXT HXT  sing N N 258 
LEU N   CA   sing N N 259 
LEU N   H    sing N N 260 
LEU N   H2   sing N N 261 
LEU CA  C    sing N N 262 
LEU CA  CB   sing N N 263 
LEU CA  HA   sing N N 264 
LEU C   O    doub N N 265 
LEU C   OXT  sing N N 266 
LEU CB  CG   sing N N 267 
LEU CB  HB2  sing N N 268 
LEU CB  HB3  sing N N 269 
LEU CG  CD1  sing N N 270 
LEU CG  CD2  sing N N 271 
LEU CG  HG   sing N N 272 
LEU CD1 HD11 sing N N 273 
LEU CD1 HD12 sing N N 274 
LEU CD1 HD13 sing N N 275 
LEU CD2 HD21 sing N N 276 
LEU CD2 HD22 sing N N 277 
LEU CD2 HD23 sing N N 278 
LEU OXT HXT  sing N N 279 
LYS N   CA   sing N N 280 
LYS N   H    sing N N 281 
LYS N   H2   sing N N 282 
LYS CA  C    sing N N 283 
LYS CA  CB   sing N N 284 
LYS CA  HA   sing N N 285 
LYS C   O    doub N N 286 
LYS C   OXT  sing N N 287 
LYS CB  CG   sing N N 288 
LYS CB  HB2  sing N N 289 
LYS CB  HB3  sing N N 290 
LYS CG  CD   sing N N 291 
LYS CG  HG2  sing N N 292 
LYS CG  HG3  sing N N 293 
LYS CD  CE   sing N N 294 
LYS CD  HD2  sing N N 295 
LYS CD  HD3  sing N N 296 
LYS CE  NZ   sing N N 297 
LYS CE  HE2  sing N N 298 
LYS CE  HE3  sing N N 299 
LYS NZ  HZ1  sing N N 300 
LYS NZ  HZ2  sing N N 301 
LYS NZ  HZ3  sing N N 302 
LYS OXT HXT  sing N N 303 
MET N   CA   sing N N 304 
MET N   H    sing N N 305 
MET N   H2   sing N N 306 
MET CA  C    sing N N 307 
MET CA  CB   sing N N 308 
MET CA  HA   sing N N 309 
MET C   O    doub N N 310 
MET C   OXT  sing N N 311 
MET CB  CG   sing N N 312 
MET CB  HB2  sing N N 313 
MET CB  HB3  sing N N 314 
MET CG  SD   sing N N 315 
MET CG  HG2  sing N N 316 
MET CG  HG3  sing N N 317 
MET SD  CE   sing N N 318 
MET CE  HE1  sing N N 319 
MET CE  HE2  sing N N 320 
MET CE  HE3  sing N N 321 
MET OXT HXT  sing N N 322 
PHE N   CA   sing N N 323 
PHE N   H    sing N N 324 
PHE N   H2   sing N N 325 
PHE CA  C    sing N N 326 
PHE CA  CB   sing N N 327 
PHE CA  HA   sing N N 328 
PHE C   O    doub N N 329 
PHE C   OXT  sing N N 330 
PHE CB  CG   sing N N 331 
PHE CB  HB2  sing N N 332 
PHE CB  HB3  sing N N 333 
PHE CG  CD1  doub Y N 334 
PHE CG  CD2  sing Y N 335 
PHE CD1 CE1  sing Y N 336 
PHE CD1 HD1  sing N N 337 
PHE CD2 CE2  doub Y N 338 
PHE CD2 HD2  sing N N 339 
PHE CE1 CZ   doub Y N 340 
PHE CE1 HE1  sing N N 341 
PHE CE2 CZ   sing Y N 342 
PHE CE2 HE2  sing N N 343 
PHE CZ  HZ   sing N N 344 
PHE OXT HXT  sing N N 345 
PRO N   CA   sing N N 346 
PRO N   CD   sing N N 347 
PRO N   H    sing N N 348 
PRO CA  C    sing N N 349 
PRO CA  CB   sing N N 350 
PRO CA  HA   sing N N 351 
PRO C   O    doub N N 352 
PRO C   OXT  sing N N 353 
PRO CB  CG   sing N N 354 
PRO CB  HB2  sing N N 355 
PRO CB  HB3  sing N N 356 
PRO CG  CD   sing N N 357 
PRO CG  HG2  sing N N 358 
PRO CG  HG3  sing N N 359 
PRO CD  HD2  sing N N 360 
PRO CD  HD3  sing N N 361 
PRO OXT HXT  sing N N 362 
SER N   CA   sing N N 363 
SER N   H    sing N N 364 
SER N   H2   sing N N 365 
SER CA  C    sing N N 366 
SER CA  CB   sing N N 367 
SER CA  HA   sing N N 368 
SER C   O    doub N N 369 
SER C   OXT  sing N N 370 
SER CB  OG   sing N N 371 
SER CB  HB2  sing N N 372 
SER CB  HB3  sing N N 373 
SER OG  HG   sing N N 374 
SER OXT HXT  sing N N 375 
THR N   CA   sing N N 376 
THR N   H    sing N N 377 
THR N   H2   sing N N 378 
THR CA  C    sing N N 379 
THR CA  CB   sing N N 380 
THR CA  HA   sing N N 381 
THR C   O    doub N N 382 
THR C   OXT  sing N N 383 
THR CB  OG1  sing N N 384 
THR CB  CG2  sing N N 385 
THR CB  HB   sing N N 386 
THR OG1 HG1  sing N N 387 
THR CG2 HG21 sing N N 388 
THR CG2 HG22 sing N N 389 
THR CG2 HG23 sing N N 390 
THR OXT HXT  sing N N 391 
TRP N   CA   sing N N 392 
TRP N   H    sing N N 393 
TRP N   H2   sing N N 394 
TRP CA  C    sing N N 395 
TRP CA  CB   sing N N 396 
TRP CA  HA   sing N N 397 
TRP C   O    doub N N 398 
TRP C   OXT  sing N N 399 
TRP CB  CG   sing N N 400 
TRP CB  HB2  sing N N 401 
TRP CB  HB3  sing N N 402 
TRP CG  CD1  doub Y N 403 
TRP CG  CD2  sing Y N 404 
TRP CD1 NE1  sing Y N 405 
TRP CD1 HD1  sing N N 406 
TRP CD2 CE2  doub Y N 407 
TRP CD2 CE3  sing Y N 408 
TRP NE1 CE2  sing Y N 409 
TRP NE1 HE1  sing N N 410 
TRP CE2 CZ2  sing Y N 411 
TRP CE3 CZ3  doub Y N 412 
TRP CE3 HE3  sing N N 413 
TRP CZ2 CH2  doub Y N 414 
TRP CZ2 HZ2  sing N N 415 
TRP CZ3 CH2  sing Y N 416 
TRP CZ3 HZ3  sing N N 417 
TRP CH2 HH2  sing N N 418 
TRP OXT HXT  sing N N 419 
TYR N   CA   sing N N 420 
TYR N   H    sing N N 421 
TYR N   H2   sing N N 422 
TYR CA  C    sing N N 423 
TYR CA  CB   sing N N 424 
TYR CA  HA   sing N N 425 
TYR C   O    doub N N 426 
TYR C   OXT  sing N N 427 
TYR CB  CG   sing N N 428 
TYR CB  HB2  sing N N 429 
TYR CB  HB3  sing N N 430 
TYR CG  CD1  doub Y N 431 
TYR CG  CD2  sing Y N 432 
TYR CD1 CE1  sing Y N 433 
TYR CD1 HD1  sing N N 434 
TYR CD2 CE2  doub Y N 435 
TYR CD2 HD2  sing N N 436 
TYR CE1 CZ   doub Y N 437 
TYR CE1 HE1  sing N N 438 
TYR CE2 CZ   sing Y N 439 
TYR CE2 HE2  sing N N 440 
TYR CZ  OH   sing N N 441 
TYR OH  HH   sing N N 442 
TYR OXT HXT  sing N N 443 
VAL N   CA   sing N N 444 
VAL N   H    sing N N 445 
VAL N   H2   sing N N 446 
VAL CA  C    sing N N 447 
VAL CA  CB   sing N N 448 
VAL CA  HA   sing N N 449 
VAL C   O    doub N N 450 
VAL C   OXT  sing N N 451 
VAL CB  CG1  sing N N 452 
VAL CB  CG2  sing N N 453 
VAL CB  HB   sing N N 454 
VAL CG1 HG11 sing N N 455 
VAL CG1 HG12 sing N N 456 
VAL CG1 HG13 sing N N 457 
VAL CG2 HG21 sing N N 458 
VAL CG2 HG22 sing N N 459 
VAL CG2 HG23 sing N N 460 
VAL OXT HXT  sing N N 461 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'P01 AI057788' 1 
'Robert A. Welch Foundation'                                                                      'United States' Q-1279         2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6nir 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9DAJ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010233 
_atom_sites.fract_transf_matrix[1][2]   0.005908 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011816 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.022411 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356  2.42580  ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 8.95735  ?        ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345  0.48472  ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
I ? ? 40.26819 12.56501 ? ? 1.42647  27.02115 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032  2.96436  ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882  3.47563  ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732  6.39887  ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . SER A 1 4   ? -15.52425 -21.61058 2.29886   1.000 36.88429  ? 4   SER A N    1 
ATOM   2    C CA   . SER A 1 4   ? -15.77189 -22.03931 3.67284   1.000 52.16097  ? 4   SER A CA   1 
ATOM   3    C C    . SER A 1 4   ? -17.26850 -22.19125 3.92103   1.000 63.50595  ? 4   SER A C    1 
ATOM   4    O O    . SER A 1 4   ? -17.71923 -23.18983 4.48165   1.000 50.91989  ? 4   SER A O    1 
ATOM   5    C CB   . SER A 1 4   ? -15.17273 -21.04594 4.66537   1.000 43.16209  ? 4   SER A CB   1 
ATOM   6    O OG   . SER A 1 4   ? -15.42500 -21.44599 6.00117   1.000 48.84397  ? 4   SER A OG   1 
ATOM   7    H HA   . SER A 1 4   ? -15.34586 -22.89790 3.82190   1.000 62.75170  ? 4   SER A HA   1 
ATOM   8    H HB2  . SER A 1 4   ? -14.21386 -21.00092 4.52588   1.000 51.95305  ? 4   SER A HB2  1 
ATOM   9    H HB3  . SER A 1 4   ? -15.57082 -20.17388 4.51729   1.000 51.95305  ? 4   SER A HB3  1 
ATOM   10   H HG   . SER A 1 4   ? -15.06493 -20.90694 6.53538   1.000 58.77130  ? 4   SER A HG   1 
ATOM   11   N N    . ILE A 1 5   ? -18.04249 -21.18492 3.51060   1.000 40.34951  ? 5   ILE A N    1 
ATOM   12   C CA   . ILE A 1 5   ? -19.49302 -21.33514 3.53285   1.000 45.08559  ? 5   ILE A CA   1 
ATOM   13   C C    . ILE A 1 5   ? -19.89331 -22.56262 2.72723   1.000 47.71227  ? 5   ILE A C    1 
ATOM   14   O O    . ILE A 1 5   ? -20.91003 -23.20680 3.01545   1.000 37.14171  ? 5   ILE A O    1 
ATOM   15   C CB   . ILE A 1 5   ? -20.17365 -20.05903 3.00207   1.000 37.94500  ? 5   ILE A CB   1 
ATOM   16   C CG1  . ILE A 1 5   ? -21.68769 -20.13408 3.21908   1.000 45.81073  ? 5   ILE A CG1  1 
ATOM   17   C CG2  . ILE A 1 5   ? -19.85115 -19.85908 1.52703   1.000 42.78596  ? 5   ILE A CG2  1 
ATOM   18   C CD1  . ILE A 1 5   ? -22.45974 -19.00119 2.56809   1.000 55.67219  ? 5   ILE A CD1  1 
ATOM   19   H H    . ILE A 1 5   ? -17.75851 -20.42594 3.22267   1.000 48.57796  ? 5   ILE A H    1 
ATOM   20   H HA   . ILE A 1 5   ? -19.78613 -21.45908 4.44916   1.000 54.26124  ? 5   ILE A HA   1 
ATOM   21   H HB   . ILE A 1 5   ? -19.83027 -19.29874 3.49700   1.000 45.69254  ? 5   ILE A HB   1 
ATOM   22   H HG12 . ILE A 1 5   ? -22.01473 -20.96731 2.84536   1.000 55.13141  ? 5   ILE A HG12 1 
ATOM   23   H HG13 . ILE A 1 5   ? -21.86736 -20.10466 4.17184   1.000 55.13141  ? 5   ILE A HG13 1 
ATOM   24   H HG21 . ILE A 1 5   ? -20.09799 -18.95713 1.26924   1.000 51.50170  ? 5   ILE A HG21 1 
ATOM   25   H HG22 . ILE A 1 5   ? -18.90025 -19.99357 1.39063   1.000 51.50170  ? 5   ILE A HG22 1 
ATOM   26   H HG23 . ILE A 1 5   ? -20.35459 -20.50218 1.00370   1.000 51.50170  ? 5   ILE A HG23 1 
ATOM   27   H HD11 . ILE A 1 5   ? -23.37460 -19.01656 2.89010   1.000 66.96517  ? 5   ILE A HD11 1 
ATOM   28   H HD12 . ILE A 1 5   ? -22.04082 -18.15818 2.80209   1.000 66.96517  ? 5   ILE A HD12 1 
ATOM   29   H HD13 . ILE A 1 5   ? -22.44574 -19.12161 1.60569   1.000 66.96517  ? 5   ILE A HD13 1 
ATOM   30   N N    . TRP A 1 6   ? -19.10257 -22.90767 1.70786   1.000 35.39897  ? 6   TRP A N    1 
ATOM   31   C CA   . TRP A 1 6   ? -19.36073 -24.12310 0.94744   1.000 47.10751  ? 6   TRP A CA   1 
ATOM   32   C C    . TRP A 1 6   ? -19.17723 -25.36761 1.80506   1.000 45.44187  ? 6   TRP A C    1 
ATOM   33   O O    . TRP A 1 6   ? -19.83384 -26.38664 1.56292   1.000 41.35630  ? 6   TRP A O    1 
ATOM   34   C CB   . TRP A 1 6   ? -18.44223 -24.18113 -0.27227  1.000 42.75299  ? 6   TRP A CB   1 
ATOM   35   C CG   . TRP A 1 6   ? -18.79125 -23.18337 -1.33758  1.000 43.67771  ? 6   TRP A CG   1 
ATOM   36   C CD1  . TRP A 1 6   ? -18.14095 -22.01506 -1.61903  1.000 38.38793  ? 6   TRP A CD1  1 
ATOM   37   C CD2  . TRP A 1 6   ? -19.88086 -23.26755 -2.26354  1.000 29.70945  ? 6   TRP A CD2  1 
ATOM   38   N NE1  . TRP A 1 6   ? -18.75682 -21.37104 -2.66601  1.000 37.13456  ? 6   TRP A NE1  1 
ATOM   39   C CE2  . TRP A 1 6   ? -19.82801 -22.11915 -3.07826  1.000 44.47749  ? 6   TRP A CE2  1 
ATOM   40   C CE3  . TRP A 1 6   ? -20.89544 -24.20395 -2.48312  1.000 37.72771  ? 6   TRP A CE3  1 
ATOM   41   C CZ2  . TRP A 1 6   ? -20.75115 -21.88374 -4.09525  1.000 52.12609  ? 6   TRP A CZ2  1 
ATOM   42   C CZ3  . TRP A 1 6   ? -21.80776 -23.96918 -3.49301  1.000 38.90568  ? 6   TRP A CZ3  1 
ATOM   43   C CH2  . TRP A 1 6   ? -21.73078 -22.81897 -4.28597  1.000 33.26003  ? 6   TRP A CH2  1 
ATOM   44   H H    . TRP A 1 6   ? -18.41904 -22.45867 1.44182   1.000 42.63731  ? 6   TRP A H    1 
ATOM   45   H HA   . TRP A 1 6   ? -20.27810 -24.10705 0.63266   1.000 56.68755  ? 6   TRP A HA   1 
ATOM   46   H HB2  . TRP A 1 6   ? -17.53236 -24.00366 0.01329   1.000 51.46213  ? 6   TRP A HB2  1 
ATOM   47   H HB3  . TRP A 1 6   ? -18.50006 -25.06624 -0.66488  1.000 51.46213  ? 6   TRP A HB3  1 
ATOM   48   H HD1  . TRP A 1 6   ? -17.39073 -21.70113 -1.16791  1.000 46.22406  ? 6   TRP A HD1  1 
ATOM   49   H HE1  . TRP A 1 6   ? -18.50992 -20.62095 -3.00660  1.000 44.72002  ? 6   TRP A HE1  1 
ATOM   50   H HE3  . TRP A 1 6   ? -20.95486 -24.97010 -1.95931  1.000 45.43179  ? 6   TRP A HE3  1 
ATOM   51   H HZ2  . TRP A 1 6   ? -20.70298 -21.12014 -4.62393  1.000 62.70985  ? 6   TRP A HZ2  1 
ATOM   52   H HZ3  . TRP A 1 6   ? -22.48547 -24.58671 -3.64880  1.000 46.84536  ? 6   TRP A HZ3  1 
ATOM   53   H HH2  . TRP A 1 6   ? -22.36004 -22.68737 -4.95799  1.000 40.07057  ? 6   TRP A HH2  1 
ATOM   54   N N    . SER A 1 7   ? -18.29676 -25.30614 2.80764   1.000 41.57440  ? 7   SER A N    1 
ATOM   55   C CA   . SER A 1 7   ? -18.09940 -26.44857 3.69070   1.000 32.03560  ? 7   SER A CA   1 
ATOM   56   C C    . SER A 1 7   ? -19.34746 -26.76506 4.50048   1.000 31.30158  ? 7   SER A C    1 
ATOM   57   O O    . SER A 1 7   ? -19.46581 -27.87626 5.02891   1.000 30.22697  ? 7   SER A O    1 
ATOM   58   C CB   . SER A 1 7   ? -16.92898 -26.18859 4.64061   1.000 48.92593  ? 7   SER A CB   1 
ATOM   59   O OG   . SER A 1 7   ? -17.33028 -25.38477 5.73733   1.000 48.11396  ? 7   SER A OG   1 
ATOM   60   H H    . SER A 1 7   ? -17.80924 -24.62228 2.99276   1.000 50.04782  ? 7   SER A H    1 
ATOM   61   H HA   . SER A 1 7   ? -17.88118 -27.22232 3.14794   1.000 38.60126  ? 7   SER A HA   1 
ATOM   62   H HB2  . SER A 1 7   ? -16.60135 -27.03773 4.97606   1.000 58.86965  ? 7   SER A HB2  1 
ATOM   63   H HB3  . SER A 1 7   ? -16.22553 -25.73000 4.15508   1.000 58.86965  ? 7   SER A HB3  1 
ATOM   64   H HG   . SER A 1 7   ? -17.64175 -24.65551 5.46025   1.000 57.89530  ? 7   SER A HG   1 
ATOM   65   N N    . ARG A 1 8   ? -20.27296 -25.81362 4.61653   1.000 39.07908  ? 8   ARG A N    1 
ATOM   66   C CA   . ARG A 1 8   ? -21.50761 -26.00081 5.36735   1.000 32.05664  ? 8   ARG A CA   1 
ATOM   67   C C    . ARG A 1 8   ? -22.56622 -26.75959 4.57863   1.000 34.49697  ? 8   ARG A C    1 
ATOM   68   O O    . ARG A 1 8   ? -23.63421 -27.04932 5.12690   1.000 28.13360  ? 8   ARG A O    1 
ATOM   69   C CB   . ARG A 1 8   ? -22.05098 -24.63511 5.80614   1.000 33.62716  ? 8   ARG A CB   1 
ATOM   70   C CG   . ARG A 1 8   ? -21.09220 -23.85027 6.70798   1.000 31.50922  ? 8   ARG A CG   1 
ATOM   71   C CD   . ARG A 1 8   ? -21.50201 -22.38315 6.84815   1.000 35.88650  ? 8   ARG A CD   1 
ATOM   72   N NE   . ARG A 1 8   ? -22.51768 -22.18644 7.87520   1.000 45.15683  ? 8   ARG A NE   1 
ATOM   73   C CZ   . ARG A 1 8   ? -22.43477 -21.30945 8.86867   1.000 38.66638  ? 8   ARG A CZ   1 
ATOM   74   N NH1  . ARG A 1 8   ? -21.40487 -20.48515 8.98447   1.000 35.67511  ? 8   ARG A NH1  1 
ATOM   75   N NH2  . ARG A 1 8   ? -23.41987 -21.24756 9.75986   1.000 35.76874  ? 8   ARG A NH2  1 
ATOM   76   H H    . ARG A 1 8   ? -20.20534 -25.03372 4.26046   1.000 47.05343  ? 8   ARG A H    1 
ATOM   77   H HA   . ARG A 1 8   ? -21.32022 -26.51617 6.16747   1.000 38.62651  ? 8   ARG A HA   1 
ATOM   78   H HB2  . ARG A 1 8   ? -22.22054 -24.09848 5.01608   1.000 40.51113  ? 8   ARG A HB2  1 
ATOM   79   H HB3  . ARG A 1 8   ? -22.87583 -24.77111 6.29811   1.000 40.51113  ? 8   ARG A HB3  1 
ATOM   80   H HG2  . ARG A 1 8   ? -21.08859 -24.24862 7.59240   1.000 37.96960  ? 8   ARG A HG2  1 
ATOM   81   H HG3  . ARG A 1 8   ? -20.20054 -23.87969 6.32722   1.000 37.96960  ? 8   ARG A HG3  1 
ATOM   82   H HD2  . ARG A 1 8   ? -20.72342 -21.85743 7.08964   1.000 43.22234  ? 8   ARG A HD2  1 
ATOM   83   H HD3  . ARG A 1 8   ? -21.86338 -22.07207 6.00343   1.000 43.22234  ? 8   ARG A HD3  1 
ATOM   84   H HE   . ARG A 1 8   ? -23.22398 -22.67541 7.83456   1.000 54.34673  ? 8   ARG A HE   1 
ATOM   85   H HH11 . ARG A 1 8   ? -20.76765 -20.50945 8.40744   1.000 42.96868  ? 8   ARG A HH11 1 
ATOM   86   H HH12 . ARG A 1 8   ? -21.37324 -19.92552 9.63671   1.000 42.96868  ? 8   ARG A HH12 1 
ATOM   87   H HH21 . ARG A 1 8   ? -24.09833 -21.77112 9.68792   1.000 43.08103  ? 8   ARG A HH21 1 
ATOM   88   H HH22 . ARG A 1 8   ? -23.37846 -20.68398 10.40814  1.000 43.08103  ? 8   ARG A HH22 1 
ATOM   89   N N    . ILE A 1 9   ? -22.29364 -27.09314 3.32022   1.000 31.68900  ? 9   ILE A N    1 
ATOM   90   C CA   . ILE A 1 9   ? -23.20273 -27.85843 2.47264   1.000 29.25995  ? 9   ILE A CA   1 
ATOM   91   C C    . ILE A 1 9   ? -22.63852 -29.26797 2.36470   1.000 33.49554  ? 9   ILE A C    1 
ATOM   92   O O    . ILE A 1 9   ? -21.48151 -29.44665 1.95989   1.000 24.68937  ? 9   ILE A O    1 
ATOM   93   C CB   . ILE A 1 9   ? -23.35690 -27.21364 1.08725   1.000 33.15328  ? 9   ILE A CB   1 
ATOM   94   C CG1  . ILE A 1 9   ? -23.87231 -25.77969 1.22323   1.000 33.42083  ? 9   ILE A CG1  1 
ATOM   95   C CG2  . ILE A 1 9   ? -24.29174 -28.04087 0.21737   1.000 37.24600  ? 9   ILE A CG2  1 
ATOM   96   C CD1  . ILE A 1 9   ? -23.59777 -24.92028 0.00799   1.000 38.55104  ? 9   ILE A CD1  1 
ATOM   97   H H    . ILE A 1 9   ? -21.56213 -26.87958 2.92160   1.000 38.18534  ? 9   ILE A H    1 
ATOM   98   H HA   . ILE A 1 9   ? -24.08000 -27.90407 2.88400   1.000 35.27048  ? 9   ILE A HA   1 
ATOM   99   H HB   . ILE A 1 9   ? -22.48571 -27.18723 0.66153   1.000 39.94247  ? 9   ILE A HB   1 
ATOM   100  H HG12 . ILE A 1 9   ? -24.83248 -25.80413 1.35879   1.000 40.26354  ? 9   ILE A HG12 1 
ATOM   101  H HG13 . ILE A 1 9   ? -23.44019 -25.36309 1.98522   1.000 40.26354  ? 9   ILE A HG13 1 
ATOM   102  H HG21 . ILE A 1 9   ? -24.50952 -27.53558 -0.58147  1.000 44.85374  ? 9   ILE A HG21 1 
ATOM   103  H HG22 . ILE A 1 9   ? -23.84758 -28.86831 -0.02545  1.000 44.85374  ? 9   ILE A HG22 1 
ATOM   104  H HG23 . ILE A 1 9   ? -25.10023 -28.23383 0.71738   1.000 44.85374  ? 9   ILE A HG23 1 
ATOM   105  H HD11 . ILE A 1 9   ? -23.93407 -24.02528 0.17163   1.000 46.41979  ? 9   ILE A HD11 1 
ATOM   106  H HD12 . ILE A 1 9   ? -22.64089 -24.89067 -0.14822  1.000 46.41979  ? 9   ILE A HD12 1 
ATOM   107  H HD13 . ILE A 1 9   ? -24.04651 -25.30695 -0.76014  1.000 46.41979  ? 9   ILE A HD13 1 
ATOM   108  N N    . VAL A 1 10  ? -23.44179 -30.26728 2.73042   1.000 29.02588  ? 10  VAL A N    1 
ATOM   109  C CA   . VAL A 1 10  ? -22.95877 -31.64162 2.82707   1.000 42.90657  ? 10  VAL A CA   1 
ATOM   110  C C    . VAL A 1 10  ? -23.99528 -32.61267 2.28139   1.000 35.22159  ? 10  VAL A C    1 
ATOM   111  O O    . VAL A 1 10  ? -25.20572 -32.41286 2.44603   1.000 34.83228  ? 10  VAL A O    1 
ATOM   112  C CB   . VAL A 1 10  ? -22.59684 -32.02108 4.27907   1.000 23.84358  ? 10  VAL A CB   1 
ATOM   113  C CG1  . VAL A 1 10  ? -21.76784 -30.92775 4.92063   1.000 46.76528  ? 10  VAL A CG1  1 
ATOM   114  C CG2  . VAL A 1 10  ? -23.85013 -32.29143 5.09790   1.000 34.18630  ? 10  VAL A CG2  1 
ATOM   115  H H    . VAL A 1 10  ? -24.27335 -30.17189 2.92793   1.000 34.98960  ? 10  VAL A H    1 
ATOM   116  H HA   . VAL A 1 10  ? -22.16905 -31.71120 2.26815   1.000 51.64643  ? 10  VAL A HA   1 
ATOM   117  H HB   . VAL A 1 10  ? -22.06968 -32.83520 4.26380   1.000 28.77083  ? 10  VAL A HB   1 
ATOM   118  H HG11 . VAL A 1 10  ? -21.42844 -31.24684 5.77145   1.000 56.27688  ? 10  VAL A HG11 1 
ATOM   119  H HG12 . VAL A 1 10  ? -21.02936 -30.70505 4.33246   1.000 56.27688  ? 10  VAL A HG12 1 
ATOM   120  H HG13 . VAL A 1 10  ? -22.32719 -30.14749 5.05928   1.000 56.27688  ? 10  VAL A HG13 1 
ATOM   121  H HG21 . VAL A 1 10  ? -23.62867 -32.23918 6.04084   1.000 41.18211  ? 10  VAL A HG21 1 
ATOM   122  H HG22 . VAL A 1 10  ? -24.52059 -31.62576 4.87820   1.000 41.18211  ? 10  VAL A HG22 1 
ATOM   123  H HG23 . VAL A 1 10  ? -24.18163 -33.17772 4.88460   1.000 41.18211  ? 10  VAL A HG23 1 
ATOM   124  N N    . ASN A 1 11  ? -23.50692 -33.67614 1.65252   1.000 33.53993  ? 11  ASN A N    1 
ATOM   125  C CA   . ASN A 1 11  ? -24.35743 -34.74248 1.14700   1.000 41.26122  ? 11  ASN A CA   1 
ATOM   126  C C    . ASN A 1 11  ? -25.28247 -35.25108 2.24183   1.000 31.44480  ? 11  ASN A C    1 
ATOM   127  O O    . ASN A 1 11  ? -24.82860 -35.65216 3.31798   1.000 35.38487  ? 11  ASN A O    1 
ATOM   128  C CB   . ASN A 1 11  ? -23.48069 -35.87930 0.61601   1.000 30.55393  ? 11  ASN A CB   1 
ATOM   129  C CG   . ASN A 1 11  ? -24.03416 -36.50512 -0.64716  1.000 44.07253  ? 11  ASN A CG   1 
ATOM   130  O OD1  . ASN A 1 11  ? -23.75477 -36.04277 -1.75329  1.000 73.34048  ? 11  ASN A OD1  1 
ATOM   131  N ND2  . ASN A 1 11  ? -24.80833 -37.57284 -0.49086  1.000 69.03760  ? 11  ASN A ND2  1 
ATOM   132  H H    . ASN A 1 11  ? -22.66983 -33.80529 1.50357   1.000 40.40646  ? 11  ASN A H    1 
ATOM   133  H HA   . ASN A 1 11  ? -24.90322 -34.40802 0.41820   1.000 49.67200  ? 11  ASN A HA   1 
ATOM   134  H HB2  . ASN A 1 11  ? -22.59788 -35.53065 0.41605   1.000 36.82326  ? 11  ASN A HB2  1 
ATOM   135  H HB3  . ASN A 1 11  ? -23.41841 -36.57246 1.29171   1.000 36.82326  ? 11  ASN A HB3  1 
ATOM   136  H HD21 . ASN A 1 11  ? -24.97170 -37.87376 0.29804   1.000 83.00366  ? 11  ASN A HD21 1 
ATOM   137  H HD22 . ASN A 1 11  ? -25.14628 -37.96333 -1.17854  1.000 83.00366  ? 11  ASN A HD22 1 
ATOM   138  N N    . PHE A 1 12  ? -26.58364 -35.23061 1.95990   1.000 38.78580  ? 12  PHE A N    1 
ATOM   139  C CA   . PHE A 1 12  ? -27.60905 -35.66139 2.90702   1.000 40.36754  ? 12  PHE A CA   1 
ATOM   140  C C    . PHE A 1 12  ? -28.63999 -36.46528 2.12633   1.000 36.61425  ? 12  PHE A C    1 
ATOM   141  O O    . PHE A 1 12  ? -29.34492 -35.90979 1.27947   1.000 31.36822  ? 12  PHE A O    1 
ATOM   142  C CB   . PHE A 1 12  ? -28.25167 -34.45788 3.60105   1.000 44.61111  ? 12  PHE A CB   1 
ATOM   143  C CG   . PHE A 1 12  ? -28.97307 -34.80158 4.87002   1.000 30.63856  ? 12  PHE A CG   1 
ATOM   144  C CD1  . PHE A 1 12  ? -28.26430 -35.12267 6.01266   1.000 23.49001  ? 12  PHE A CD1  1 
ATOM   145  C CD2  . PHE A 1 12  ? -30.35546 -34.78776 4.92622   1.000 28.24355  ? 12  PHE A CD2  1 
ATOM   146  C CE1  . PHE A 1 12  ? -28.91738 -35.43797 7.18298   1.000 29.79688  ? 12  PHE A CE1  1 
ATOM   147  C CE2  . PHE A 1 12  ? -31.01532 -35.10249 6.09655   1.000 40.24482  ? 12  PHE A CE2  1 
ATOM   148  C CZ   . PHE A 1 12  ? -30.29448 -35.42732 7.22626   1.000 27.29642  ? 12  PHE A CZ   1 
ATOM   149  H H    . PHE A 1 12  ? -26.90511 -34.96474 1.20786   1.000 46.70151  ? 12  PHE A H    1 
ATOM   150  H HA   . PHE A 1 12  ? -27.22068 -36.23282 3.58786   1.000 48.59959  ? 12  PHE A HA   1 
ATOM   151  H HB2  . PHE A 1 12  ? -27.55689 -33.81753 3.82042   1.000 53.69188  ? 12  PHE A HB2  1 
ATOM   152  H HB3  . PHE A 1 12  ? -28.89415 -34.05593 2.99562   1.000 53.69188  ? 12  PHE A HB3  1 
ATOM   153  H HD1  . PHE A 1 12  ? -27.33457 -35.12573 5.99055   1.000 28.34655  ? 12  PHE A HD1  1 
ATOM   154  H HD2  . PHE A 1 12  ? -30.84482 -34.56412 4.16766   1.000 34.05080  ? 12  PHE A HD2  1 
ATOM   155  H HE1  . PHE A 1 12  ? -28.42948 -35.65793 7.94355   1.000 35.91480  ? 12  PHE A HE1  1 
ATOM   156  H HE2  . PHE A 1 12  ? -31.94490 -35.09553 6.12334   1.000 48.45232  ? 12  PHE A HE2  1 
ATOM   157  H HZ   . PHE A 1 12  ? -30.73719 -35.63891 8.01628   1.000 32.91425  ? 12  PHE A HZ   1 
ATOM   158  N N    . GLY A 1 13  ? -28.71982 -37.76491 2.39365   1.000 35.30534  ? 13  GLY A N    1 
ATOM   159  C CA   . GLY A 1 13  ? -29.66163 -38.59853 1.66436   1.000 37.15596  ? 13  GLY A CA   1 
ATOM   160  C C    . GLY A 1 13  ? -29.49531 -38.44822 0.16594   1.000 37.10770  ? 13  GLY A C    1 
ATOM   161  O O    . GLY A 1 13  ? -28.37982 -38.47702 -0.36721  1.000 38.65675  ? 13  GLY A O    1 
ATOM   162  H H    . GLY A 1 13  ? -28.24855 -38.17973 2.98138   1.000 42.52495  ? 13  GLY A H    1 
ATOM   163  H HA2  . GLY A 1 13  ? -29.52037 -39.52911 1.89882   1.000 44.74569  ? 13  GLY A HA2  1 
ATOM   164  H HA3  . GLY A 1 13  ? -30.56814 -38.34732 1.90107   1.000 44.74569  ? 13  GLY A HA3  1 
ATOM   165  N N    . SER A 1 14  ? -30.61482 -38.28566 -0.53424  1.000 29.01225  ? 14  SER A N    1 
ATOM   166  C CA   . SER A 1 14  ? -30.60487 -38.08949 -1.97874  1.000 35.10009  ? 14  SER A CA   1 
ATOM   167  C C    . SER A 1 14  ? -30.36825 -36.63478 -2.37565  1.000 36.09393  ? 14  SER A C    1 
ATOM   168  O O    . SER A 1 14  ? -30.43379 -36.30933 -3.56664  1.000 27.26160  ? 14  SER A O    1 
ATOM   169  C CB   . SER A 1 14  ? -31.92270 -38.59196 -2.57687  1.000 29.50422  ? 14  SER A CB   1 
ATOM   170  O OG   . SER A 1 14  ? -33.03842 -38.02471 -1.91069  1.000 41.00535  ? 14  SER A OG   1 
ATOM   171  H H    . SER A 1 14  ? -31.40271 -38.28534 -0.18953  1.000 34.97324  ? 14  SER A H    1 
ATOM   172  H HA   . SER A 1 14  ? -29.88525 -38.61532 -2.36155  1.000 42.27865  ? 14  SER A HA   1 
ATOM   173  H HB2  . SER A 1 14  ? -31.95704 -38.34418 -3.51406  1.000 35.56360  ? 14  SER A HB2  1 
ATOM   174  H HB3  . SER A 1 14  ? -31.96062 -39.55707 -2.48727  1.000 35.56360  ? 14  SER A HB3  1 
ATOM   175  H HG   . SER A 1 14  ? -33.75068 -38.34835 -2.21654  1.000 49.36496  ? 14  SER A HG   1 
ATOM   176  N N    . GLY A 1 15  ? -30.08902 -35.76016 -1.41422  1.000 24.63770  ? 15  GLY A N    1 
ATOM   177  C CA   . GLY A 1 15  ? -29.84730 -34.36430 -1.71134  1.000 37.66543  ? 15  GLY A CA   1 
ATOM   178  C C    . GLY A 1 15  ? -28.75317 -33.76719 -0.85503  1.000 32.45669  ? 15  GLY A C    1 
ATOM   179  O O    . GLY A 1 15  ? -27.65368 -34.32184 -0.77362  1.000 29.31414  ? 15  GLY A O    1 
ATOM   180  H H    . GLY A 1 15  ? -30.03466 -35.95656 -0.57871  1.000 29.72378  ? 15  GLY A H    1 
ATOM   181  H HA2  . GLY A 1 15  ? -29.58847 -34.27562 -2.64195  1.000 45.35705  ? 15  GLY A HA2  1 
ATOM   182  H HA3  . GLY A 1 15  ? -30.66182 -33.85958 -1.56061  1.000 45.35705  ? 15  GLY A HA3  1 
ATOM   183  N N    . TRP A 1 16  ? -29.03638 -32.64013 -0.20477  1.000 33.62622  ? 16  TRP A N    1 
ATOM   184  C CA   . TRP A 1 16  ? -28.02578 -31.90070 0.53534   1.000 23.10090  ? 16  TRP A CA   1 
ATOM   185  C C    . TRP A 1 16  ? -28.65580 -31.28353 1.77443   1.000 35.23937  ? 16  TRP A C    1 
ATOM   186  O O    . TRP A 1 16  ? -29.87712 -31.28899 1.95030   1.000 32.17928  ? 16  TRP A O    1 
ATOM   187  C CB   . TRP A 1 16  ? -27.37774 -30.82265 -0.35151  1.000 23.35971  ? 16  TRP A CB   1 
ATOM   188  C CG   . TRP A 1 16  ? -26.75604 -31.38411 -1.60933  1.000 29.84181  ? 16  TRP A CG   1 
ATOM   189  C CD1  . TRP A 1 16  ? -27.38203 -31.62674 -2.79969  1.000 20.26031  ? 16  TRP A CD1  1 
ATOM   190  C CD2  . TRP A 1 16  ? -25.39212 -31.78224 -1.78833  1.000 37.76860  ? 16  TRP A CD2  1 
ATOM   191  N NE1  . TRP A 1 16  ? -26.48928 -32.14768 -3.70867  1.000 28.13642  ? 16  TRP A NE1  1 
ATOM   192  C CE2  . TRP A 1 16  ? -25.26168 -32.25296 -3.11105  1.000 34.96944  ? 16  TRP A CE2  1 
ATOM   193  C CE3  . TRP A 1 16  ? -24.26769 -31.78416 -0.95904  1.000 21.98613  ? 16  TRP A CE3  1 
ATOM   194  C CZ2  . TRP A 1 16  ? -24.05388 -32.71968 -3.62056  1.000 22.64494  ? 16  TRP A CZ2  1 
ATOM   195  C CZ3  . TRP A 1 16  ? -23.07088 -32.24832 -1.46695  1.000 32.67426  ? 16  TRP A CZ3  1 
ATOM   196  C CH2  . TRP A 1 16  ? -22.97289 -32.71027 -2.78447  1.000 34.03060  ? 16  TRP A CH2  1 
ATOM   197  H H    . TRP A 1 16  ? -29.81775 -32.28179 -0.17917  1.000 40.51000  ? 16  TRP A H    1 
ATOM   198  H HA   . TRP A 1 16  ? -27.33301 -32.50948 0.83594   1.000 27.87962  ? 16  TRP A HA   1 
ATOM   199  H HB2  . TRP A 1 16  ? -28.05679 -30.18177 -0.61431  1.000 28.19019  ? 16  TRP A HB2  1 
ATOM   200  H HB3  . TRP A 1 16  ? -26.67952 -30.37773 0.15390   1.000 28.19019  ? 16  TRP A HB3  1 
ATOM   201  H HD1  . TRP A 1 16  ? -28.28144 -31.46345 -2.97088  1.000 24.47091  ? 16  TRP A HD1  1 
ATOM   202  H HE1  . TRP A 1 16  ? -26.67237 -32.37045 -4.51889  1.000 33.92225  ? 16  TRP A HE1  1 
ATOM   203  H HE3  . TRP A 1 16  ? -24.32435 -31.47885 -0.08242  1.000 26.54189  ? 16  TRP A HE3  1 
ATOM   204  H HZ2  . TRP A 1 16  ? -23.98495 -33.02608 -4.49592  1.000 27.33246  ? 16  TRP A HZ2  1 
ATOM   205  H HZ3  . TRP A 1 16  ? -22.31601 -32.25415 -0.92378  1.000 39.36765  ? 16  TRP A HZ3  1 
ATOM   206  H HH2  . TRP A 1 16  ? -22.15324 -33.01792 -3.09821  1.000 40.99526  ? 16  TRP A HH2  1 
ATOM   207  N N    . GLY A 1 17  ? -27.79835 -30.76377 2.65278   1.000 45.25242  ? 17  GLY A N    1 
ATOM   208  C CA   . GLY A 1 17  ? -28.24253 -30.02826 3.81942   1.000 30.76915  ? 17  GLY A CA   1 
ATOM   209  C C    . GLY A 1 17  ? -27.20457 -28.99033 4.18757   1.000 26.93973  ? 17  GLY A C    1 
ATOM   210  O O    . GLY A 1 17  ? -26.08307 -28.99680 3.67641   1.000 29.17276  ? 17  GLY A O    1 
ATOM   211  H H    . GLY A 1 17  ? -26.94313 -30.82780 2.58881   1.000 54.46144  ? 17  GLY A H    1 
ATOM   212  H HA2  . GLY A 1 17  ? -29.08378 -29.58331 3.63174   1.000 37.08152  ? 17  GLY A HA2  1 
ATOM   213  H HA3  . GLY A 1 17  ? -28.36542 -30.63356 4.56737   1.000 37.08152  ? 17  GLY A HA3  1 
ATOM   214  N N    . PHE A 1 18  ? -27.58493 -28.10120 5.10301   1.000 28.60136  ? 18  PHE A N    1 
ATOM   215  C CA   . PHE A 1 18  ? -26.79245 -26.91252 5.39671   1.000 32.27956  ? 18  PHE A CA   1 
ATOM   216  C C    . PHE A 1 18  ? -26.74278 -26.66231 6.89509   1.000 30.90042  ? 18  PHE A C    1 
ATOM   217  O O    . PHE A 1 18  ? -27.77701 -26.68536 7.56770   1.000 22.80425  ? 18  PHE A O    1 
ATOM   218  C CB   . PHE A 1 18  ? -27.38672 -25.70253 4.65935   1.000 24.19059  ? 18  PHE A CB   1 
ATOM   219  C CG   . PHE A 1 18  ? -26.68196 -24.41046 4.93053   1.000 35.20238  ? 18  PHE A CG   1 
ATOM   220  C CD1  . PHE A 1 18  ? -25.51216 -24.08970 4.26419   1.000 27.78266  ? 18  PHE A CD1  1 
ATOM   221  C CD2  . PHE A 1 18  ? -27.20476 -23.50134 5.83270   1.000 26.00607  ? 18  PHE A CD2  1 
ATOM   222  C CE1  . PHE A 1 18  ? -24.86929 -22.89333 4.50461   1.000 28.03478  ? 18  PHE A CE1  1 
ATOM   223  C CE2  . PHE A 1 18  ? -26.56656 -22.30577 6.07703   1.000 38.98463  ? 18  PHE A CE2  1 
ATOM   224  C CZ   . PHE A 1 18  ? -25.39633 -22.00060 5.41188   1.000 31.40964  ? 18  PHE A CZ   1 
ATOM   225  H H    . PHE A 1 18  ? -28.30406 -28.16617 5.57016   1.000 34.48017  ? 18  PHE A H    1 
ATOM   226  H HA   . PHE A 1 18  ? -25.87506 -27.04774 5.11209   1.000 38.89402  ? 18  PHE A HA   1 
ATOM   227  H HB2  . PHE A 1 18  ? -27.34032 -25.86791 3.70468   1.000 29.18725  ? 18  PHE A HB2  1 
ATOM   228  H HB3  . PHE A 1 18  ? -28.31119 -25.59616 4.93308   1.000 29.18725  ? 18  PHE A HB3  1 
ATOM   229  H HD1  . PHE A 1 18  ? -25.15556 -24.68750 3.64744   1.000 33.49773  ? 18  PHE A HD1  1 
ATOM   230  H HD2  . PHE A 1 18  ? -27.99607 -23.69979 6.27919   1.000 31.36583  ? 18  PHE A HD2  1 
ATOM   231  H HE1  . PHE A 1 18  ? -24.08116 -22.68960 4.05489   1.000 33.80028  ? 18  PHE A HE1  1 
ATOM   232  H HE2  . PHE A 1 18  ? -26.92384 -21.70435 6.68985   1.000 46.94009  ? 18  PHE A HE2  1 
ATOM   233  H HZ   . PHE A 1 18  ? -24.96428 -21.19355 5.57591   1.000 37.85011  ? 18  PHE A HZ   1 
ATOM   234  N N    . TRP A 1 19  ? -25.53556 -26.43121 7.41264   1.000 32.86181  ? 19  TRP A N    1 
ATOM   235  C CA   . TRP A 1 19  ? -25.34501 -26.09860 8.82291   1.000 38.76551  ? 19  TRP A CA   1 
ATOM   236  C C    . TRP A 1 19  ? -25.57248 -24.60309 9.00075   1.000 34.90644  ? 19  TRP A C    1 
ATOM   237  O O    . TRP A 1 19  ? -24.70245 -23.78716 8.68566   1.000 34.77328  ? 19  TRP A O    1 
ATOM   238  C CB   . TRP A 1 19  ? -23.94899 -26.48937 9.29869   1.000 26.60243  ? 19  TRP A CB   1 
ATOM   239  C CG   . TRP A 1 19  ? -23.72939 -27.96382 9.41609   1.000 37.96880  ? 19  TRP A CG   1 
ATOM   240  C CD1  . TRP A 1 19  ? -23.06448 -28.76692 8.53467   1.000 29.37299  ? 19  TRP A CD1  1 
ATOM   241  C CD2  . TRP A 1 19  ? -24.17667 -28.81609 10.47653  1.000 34.22213  ? 19  TRP A CD2  1 
ATOM   242  N NE1  . TRP A 1 19  ? -23.07124 -30.06650 8.98104   1.000 26.69634  ? 19  TRP A NE1  1 
ATOM   243  C CE2  . TRP A 1 19  ? -23.74872 -30.12301 10.17112  1.000 36.88007  ? 19  TRP A CE2  1 
ATOM   244  C CE3  . TRP A 1 19  ? -24.89886 -28.60116 11.65410  1.000 29.91359  ? 19  TRP A CE3  1 
ATOM   245  C CZ2  . TRP A 1 19  ? -24.01802 -31.20864 10.99976  1.000 34.76491  ? 19  TRP A CZ2  1 
ATOM   246  C CZ3  . TRP A 1 19  ? -25.16662 -29.68198 12.47482  1.000 37.39197  ? 19  TRP A CZ3  1 
ATOM   247  C CH2  . TRP A 1 19  ? -24.72753 -30.96803 12.14374  1.000 35.76159  ? 19  TRP A CH2  1 
ATOM   248  H H    . TRP A 1 19  ? -24.80400 -26.46162 6.96154   1.000 39.59272  ? 19  TRP A H    1 
ATOM   249  H HA   . TRP A 1 19  ? -25.99739 -26.58637 9.34957   1.000 46.67715  ? 19  TRP A HA   1 
ATOM   250  H HB2  . TRP A 1 19  ? -23.29857 -26.14495 8.66685   1.000 32.08146  ? 19  TRP A HB2  1 
ATOM   251  H HB3  . TRP A 1 19  ? -23.79962 -26.09955 10.17427  1.000 32.08146  ? 19  TRP A HB3  1 
ATOM   252  H HD1  . TRP A 1 19  ? -22.66500 -28.47659 7.74662   1.000 35.40613  ? 19  TRP A HD1  1 
ATOM   253  H HE1  . TRP A 1 19  ? -22.70941 -30.73525 8.57923   1.000 32.19415  ? 19  TRP A HE1  1 
ATOM   254  H HE3  . TRP A 1 19  ? -25.19333 -27.74872 11.88109  1.000 36.05485  ? 19  TRP A HE3  1 
ATOM   255  H HZ2  . TRP A 1 19  ? -23.72652 -32.06491 10.78360  1.000 41.87644  ? 19  TRP A HZ2  1 
ATOM   256  H HZ3  . TRP A 1 19  ? -25.64693 -29.55126 13.26039  1.000 45.02891  ? 19  TRP A HZ3  1 
ATOM   257  H HH2  . TRP A 1 19  ? -24.92259 -31.67574 12.71470  1.000 43.07244  ? 19  TRP A HH2  1 
ATOM   258  N N    . VAL A 1 20  ? -26.75158 -24.23238 9.50167   1.000 33.71128  ? 20  VAL A N    1 
ATOM   259  C CA   . VAL A 1 20  ? -26.97756 -22.83485 9.84800   1.000 30.17225  ? 20  VAL A CA   1 
ATOM   260  C C    . VAL A 1 20  ? -26.08766 -22.44877 11.02182  1.000 33.46086  ? 20  VAL A C    1 
ATOM   261  O O    . VAL A 1 20  ? -25.60637 -21.31166 11.10524  1.000 30.38020  ? 20  VAL A O    1 
ATOM   262  C CB   . VAL A 1 20  ? -28.46564 -22.58913 10.15995  1.000 39.83813  ? 20  VAL A CB   1 
ATOM   263  C CG1  . VAL A 1 20  ? -28.73237 -21.10091 10.35409  1.000 33.36227  ? 20  VAL A CG1  1 
ATOM   264  C CG2  . VAL A 1 20  ? -29.35825 -23.16109 9.05616   1.000 27.43518  ? 20  VAL A CG2  1 
ATOM   265  H H    . VAL A 1 20  ? -27.41744 -24.75716 9.64599   1.000 40.61208  ? 20  VAL A H    1 
ATOM   266  H HA   . VAL A 1 20  ? -26.74607 -22.27880 9.08766   1.000 36.36524  ? 20  VAL A HA   1 
ATOM   267  H HB   . VAL A 1 20  ? -28.68777 -23.04668 10.98590  1.000 47.96430  ? 20  VAL A HB   1 
ATOM   268  H HG11 . VAL A 1 20  ? -29.68629 -20.96259 10.46272  1.000 40.19327  ? 20  VAL A HG11 1 
ATOM   269  H HG12 . VAL A 1 20  ? -28.26171 -20.79635 11.14568  1.000 40.19327  ? 20  VAL A HG12 1 
ATOM   270  H HG13 . VAL A 1 20  ? -28.41489 -20.61885 9.57452   1.000 40.19327  ? 20  VAL A HG13 1 
ATOM   271  H HG21 . VAL A 1 20  ? -30.26718 -22.85109 9.19270   1.000 33.08075  ? 20  VAL A HG21 1 
ATOM   272  H HG22 . VAL A 1 20  ? -29.03063 -22.85644 8.19549   1.000 33.08075  ? 20  VAL A HG22 1 
ATOM   273  H HG23 . VAL A 1 20  ? -29.32950 -24.12980 9.09701   1.000 33.08075  ? 20  VAL A HG23 1 
ATOM   274  N N    . SER A 1 21  ? -25.83946 -23.38838 11.93109  1.000 34.84743  ? 21  SER A N    1 
ATOM   275  C CA   . SER A 1 21  ? -25.01717 -23.16710 13.11144  1.000 39.35512  ? 21  SER A CA   1 
ATOM   276  C C    . SER A 1 21  ? -24.27856 -24.46030 13.43562  1.000 35.97680  ? 21  SER A C    1 
ATOM   277  O O    . SER A 1 21  ? -24.40470 -25.44673 12.69889  1.000 41.33926  ? 21  SER A O    1 
ATOM   278  C CB   . SER A 1 21  ? -25.87635 -22.73079 14.29694  1.000 31.99929  ? 21  SER A CB   1 
ATOM   279  O OG   . SER A 1 21  ? -26.33813 -23.85406 15.02679  1.000 45.11212  ? 21  SER A OG   1 
ATOM   280  H H    . SER A 1 21  ? -26.14776 -24.18979 11.88331  1.000 41.97546  ? 21  SER A H    1 
ATOM   281  H HA   . SER A 1 21  ? -24.37221 -22.46258 12.94237  1.000 47.38469  ? 21  SER A HA   1 
ATOM   282  H HB2  . SER A 1 21  ? -25.34404 -22.17061 14.88323  1.000 38.55769  ? 21  SER A HB2  1 
ATOM   283  H HB3  . SER A 1 21  ? -26.64064 -22.23320 13.96655  1.000 38.55769  ? 21  SER A HB3  1 
ATOM   284  H HG   . SER A 1 21  ? -26.75971 -23.60071 15.70772  1.000 54.29308  ? 21  SER A HG   1 
ATOM   285  N N    . PRO A 1 22  ? -23.50440 -24.50550 14.52021  1.000 37.23096  ? 22  PRO A N    1 
ATOM   286  C CA   . PRO A 1 22  ? -22.90592 -25.78641 14.92658  1.000 40.57975  ? 22  PRO A CA   1 
ATOM   287  C C    . PRO A 1 22  ? -23.93202 -26.84085 15.29675  1.000 34.75264  ? 22  PRO A C    1 
ATOM   288  O O    . PRO A 1 22  ? -23.60773 -28.03399 15.25949  1.000 39.96970  ? 22  PRO A O    1 
ATOM   289  C CB   . PRO A 1 22  ? -22.03824 -25.40426 16.13503  1.000 43.47896  ? 22  PRO A CB   1 
ATOM   290  C CG   . PRO A 1 22  ? -21.77077 -23.94381 15.96637  1.000 33.08293  ? 22  PRO A CG   1 
ATOM   291  C CD   . PRO A 1 22  ? -23.01227 -23.38162 15.33767  1.000 48.50928  ? 22  PRO A CD   1 
ATOM   292  H HA   . PRO A 1 22  ? -22.33593 -26.12604 14.21900  1.000 48.85424  ? 22  PRO A HA   1 
ATOM   293  H HB2  . PRO A 1 22  ? -22.52237 -25.57650 16.95774  1.000 52.33329  ? 22  PRO A HB2  1 
ATOM   294  H HB3  . PRO A 1 22  ? -21.21230 -25.91278 16.12345  1.000 52.33329  ? 22  PRO A HB3  1 
ATOM   295  H HG2  . PRO A 1 22  ? -21.60742 -23.53710 16.83171  1.000 39.85806  ? 22  PRO A HG2  1 
ATOM   296  H HG3  . PRO A 1 22  ? -21.00233 -23.81457 15.38870  1.000 39.85806  ? 22  PRO A HG3  1 
ATOM   297  H HD2  . PRO A 1 22  ? -23.66200 -23.13414 16.01406  1.000 58.36967  ? 22  PRO A HD2  1 
ATOM   298  H HD3  . PRO A 1 22  ? -22.80289 -22.61440 14.78231  1.000 58.36967  ? 22  PRO A HD3  1 
ATOM   299  N N    . SER A 1 23  ? -25.15745 -26.43950 15.65184  1.000 49.65457  ? 23  SER A N    1 
ATOM   300  C CA   . SER A 1 23  ? -26.18920 -27.35530 16.11338  1.000 33.27444  ? 23  SER A CA   1 
ATOM   301  C C    . SER A 1 23  ? -27.39869 -27.44547 15.19975  1.000 37.14644  ? 23  SER A C    1 
ATOM   302  O O    . SER A 1 23  ? -28.17667 -28.39915 15.33358  1.000 37.21786  ? 23  SER A O    1 
ATOM   303  C CB   . SER A 1 23  ? -26.69258 -26.94375 17.50918  1.000 30.83642  ? 23  SER A CB   1 
ATOM   304  O OG   . SER A 1 23  ? -25.82996 -27.39956 18.53318  1.000 57.81630  ? 23  SER A OG   1 
ATOM   305  H H    . SER A 1 23  ? -25.41585 -25.61950 15.63136  1.000 59.74402  ? 23  SER A H    1 
ATOM   306  H HA   . SER A 1 23  ? -25.79340 -28.23859 16.17693  1.000 40.08787  ? 23  SER A HA   1 
ATOM   307  H HB2  . SER A 1 23  ? -26.74170 -25.97587 17.55035  1.000 37.16224  ? 23  SER A HB2  1 
ATOM   308  H HB3  . SER A 1 23  ? -27.57268 -27.32684 17.64901  1.000 37.16224  ? 23  SER A HB3  1 
ATOM   309  H HG   . SER A 1 23  ? -26.14632 -27.20004 19.28532  1.000 69.53811  ? 23  SER A HG   1 
ATOM   310  N N    . LEU A 1 24  ? -27.59525 -26.48976 14.29784  1.000 39.91643  ? 24  LEU A N    1 
ATOM   311  C CA   . LEU A 1 24  ? -28.77800 -26.44089 13.45035  1.000 26.69278  ? 24  LEU A CA   1 
ATOM   312  C C    . LEU A 1 24  ? -28.41934 -26.87712 12.03604  1.000 24.01173  ? 24  LEU A C    1 
ATOM   313  O O    . LEU A 1 24  ? -27.47899 -26.34718 11.43419  1.000 29.29758  ? 24  LEU A O    1 
ATOM   314  C CB   . LEU A 1 24  ? -29.37679 -25.03434 13.43393  1.000 39.75279  ? 24  LEU A CB   1 
ATOM   315  C CG   . LEU A 1 24  ? -30.78944 -24.92212 12.85691  1.000 49.60005  ? 24  LEU A CG   1 
ATOM   316  C CD1  . LEU A 1 24  ? -31.75679 -25.78496 13.65606  1.000 44.38897  ? 24  LEU A CD1  1 
ATOM   317  C CD2  . LEU A 1 24  ? -31.25534 -23.47397 12.83298  1.000 35.73989  ? 24  LEU A CD2  1 
ATOM   318  H H    . LEU A 1 24  ? -27.04440 -25.84470 14.15617  1.000 48.05826  ? 24  LEU A H    1 
ATOM   319  H HA   . LEU A 1 24  ? -29.44543 -27.05411 13.79589  1.000 32.18987  ? 24  LEU A HA   1 
ATOM   320  H HB2  . LEU A 1 24  ? -29.41115 -24.70821 14.34681  1.000 47.86188  ? 24  LEU A HB2  1 
ATOM   321  H HB3  . LEU A 1 24  ? -28.80079 -24.46527 12.89979  1.000 47.86188  ? 24  LEU A HB3  1 
ATOM   322  H HG   . LEU A 1 24  ? -30.78038 -25.24219 11.94128  1.000 59.67860  ? 24  LEU A HG   1 
ATOM   323  H HD11 . LEU A 1 24  ? -32.66502 -25.50908 13.45632  1.000 53.42530  ? 24  LEU A HD11 1 
ATOM   324  H HD12 . LEU A 1 24  ? -31.63096 -26.71398 13.40708  1.000 53.42530  ? 24  LEU A HD12 1 
ATOM   325  H HD13 . LEU A 1 24  ? -31.57622 -25.66865 14.60198  1.000 53.42530  ? 24  LEU A HD13 1 
ATOM   326  H HD21 . LEU A 1 24  ? -32.15222 -23.43680 12.46537  1.000 43.04641  ? 24  LEU A HD21 1 
ATOM   327  H HD22 . LEU A 1 24  ? -31.25449 -23.12695 13.73878  1.000 43.04641  ? 24  LEU A HD22 1 
ATOM   328  H HD23 . LEU A 1 24  ? -30.64945 -22.95639 12.27990  1.000 43.04641  ? 24  LEU A HD23 1 
ATOM   329  N N    . PHE A 1 25  ? -29.18609 -27.83008 11.50898  1.000 37.95287  ? 25  PHE A N    1 
ATOM   330  C CA   . PHE A 1 25  ? -28.98026 -28.40409 10.18513  1.000 20.97777  ? 25  PHE A CA   1 
ATOM   331  C C    . PHE A 1 25  ? -30.32052 -28.45712 9.46668   1.000 29.49813  ? 25  PHE A C    1 
ATOM   332  O O    . PHE A 1 25  ? -31.28327 -29.01955 9.99708   1.000 37.81805  ? 25  PHE A O    1 
ATOM   333  C CB   . PHE A 1 25  ? -28.37196 -29.80239 10.31356  1.000 27.99270  ? 25  PHE A CB   1 
ATOM   334  C CG   . PHE A 1 25  ? -27.95206 -30.40822 9.01362   1.000 35.82242  ? 25  PHE A CG   1 
ATOM   335  C CD1  . PHE A 1 25  ? -26.75712 -30.04436 8.42116   1.000 35.74984  ? 25  PHE A CD1  1 
ATOM   336  C CD2  . PHE A 1 25  ? -28.74018 -31.35877 8.39403   1.000 26.83875  ? 25  PHE A CD2  1 
ATOM   337  C CE1  . PHE A 1 25  ? -26.36713 -30.60652 7.22882   1.000 31.53921  ? 25  PHE A CE1  1 
ATOM   338  C CE2  . PHE A 1 25  ? -28.35179 -31.92555 7.20224   1.000 36.44991  ? 25  PHE A CE2  1 
ATOM   339  C CZ   . PHE A 1 25  ? -27.16185 -31.55290 6.62280   1.000 33.33412  ? 25  PHE A CZ   1 
ATOM   340  H H    . PHE A 1 25  ? -29.85998 -28.17353 11.91825  1.000 45.70199  ? 25  PHE A H    1 
ATOM   341  H HA   . PHE A 1 25  ? -28.38159 -27.85398 9.65609   1.000 25.33187  ? 25  PHE A HA   1 
ATOM   342  H HB2  . PHE A 1 25  ? -27.58670 -29.74837 10.88044  1.000 33.74978  ? 25  PHE A HB2  1 
ATOM   343  H HB3  . PHE A 1 25  ? -29.03026 -30.39165 10.71395  1.000 33.74978  ? 25  PHE A HB3  1 
ATOM   344  H HD1  . PHE A 1 25  ? -26.21204 -29.41340 8.83308   1.000 43.05835  ? 25  PHE A HD1  1 
ATOM   345  H HD2  . PHE A 1 25  ? -29.54212 -31.61836 8.78697   1.000 32.36504  ? 25  PHE A HD2  1 
ATOM   346  H HE1  . PHE A 1 25  ? -25.56692 -30.34758 6.83195   1.000 38.00559  ? 25  PHE A HE1  1 
ATOM   347  H HE2  . PHE A 1 25  ? -28.89287 -32.55934 6.78939   1.000 43.89844  ? 25  PHE A HE2  1 
ATOM   348  H HZ   . PHE A 1 25  ? -26.89385 -31.94049 5.82102   1.000 40.15949  ? 25  PHE A HZ   1 
ATOM   349  N N    . ILE A 1 26  ? -30.38992 -27.87272 8.26760   1.000 29.00886  ? 26  ILE A N    1 
ATOM   350  C CA   . ILE A 1 26  ? -31.64770 -27.77329 7.53634   1.000 28.23572  ? 26  ILE A CA   1 
ATOM   351  C C    . ILE A 1 26  ? -31.51419 -28.47345 6.19175   1.000 22.04333  ? 26  ILE A C    1 
ATOM   352  O O    . ILE A 1 26  ? -30.43567 -28.50341 5.59012   1.000 35.48746  ? 26  ILE A O    1 
ATOM   353  C CB   . ILE A 1 26  ? -32.09208 -26.30754 7.33567   1.000 22.11426  ? 26  ILE A CB   1 
ATOM   354  C CG1  . ILE A 1 26  ? -31.11963 -25.55709 6.42536   1.000 31.58138  ? 26  ILE A CG1  1 
ATOM   355  C CG2  . ILE A 1 26  ? -32.19371 -25.60108 8.67774   1.000 27.82039  ? 26  ILE A CG2  1 
ATOM   356  C CD1  . ILE A 1 26  ? -31.52245 -24.11857 6.17444   1.000 24.71816  ? 26  ILE A CD1  1 
ATOM   357  H H    . ILE A 1 26  ? -29.71726 -27.52628 7.85881   1.000 34.96917  ? 26  ILE A H    1 
ATOM   358  H HA   . ILE A 1 26  ? -32.33080 -28.23458 8.04772   1.000 34.04141  ? 26  ILE A HA   1 
ATOM   359  H HB   . ILE A 1 26  ? -32.96362 -26.31731 6.90997   1.000 26.69566  ? 26  ILE A HB   1 
ATOM   360  H HG12 . ILE A 1 26  ? -30.24233 -25.55302 6.83916   1.000 38.05619  ? 26  ILE A HG12 1 
ATOM   361  H HG13 . ILE A 1 26  ? -31.08002 -26.00929 5.56814   1.000 38.05619  ? 26  ILE A HG13 1 
ATOM   362  H HG21 . ILE A 1 26  ? -32.66327 -24.76086 8.55758   1.000 33.54300  ? 26  ILE A HG21 1 
ATOM   363  H HG22 . ILE A 1 26  ? -32.68142 -26.16703 9.29640   1.000 33.54300  ? 26  ILE A HG22 1 
ATOM   364  H HG23 . ILE A 1 26  ? -31.29978 -25.43504 9.01571   1.000 33.54300  ? 26  ILE A HG23 1 
ATOM   365  H HD11 . ILE A 1 26  ? -30.96803 -23.75421 5.46679   1.000 29.82033  ? 26  ILE A HD11 1 
ATOM   366  H HD12 . ILE A 1 26  ? -32.45534 -24.09340 5.90991   1.000 29.82033  ? 26  ILE A HD12 1 
ATOM   367  H HD13 . ILE A 1 26  ? -31.39591 -23.60839 6.98967   1.000 29.82033  ? 26  ILE A HD13 1 
ATOM   368  N N    . THR A 1 27  ? -32.62637 -29.03271 5.71736   1.000 25.97698  ? 27  THR A N    1 
ATOM   369  C CA   . THR A 1 27  ? -32.63326 -29.78597 4.47072   1.000 29.81068  ? 27  THR A CA   1 
ATOM   370  C C    . THR A 1 27  ? -34.04699 -29.78058 3.89765   1.000 29.17638  ? 27  THR A C    1 
ATOM   371  O O    . THR A 1 27  ? -34.95084 -29.12217 4.41917   1.000 32.67365  ? 27  THR A O    1 
ATOM   372  C CB   . THR A 1 27  ? -32.13433 -31.21944 4.68428   1.000 30.01718  ? 27  THR A CB   1 
ATOM   373  O OG1  . THR A 1 27  ? -32.14351 -31.92022 3.43408   1.000 31.25740  ? 27  THR A OG1  1 
ATOM   374  C CG2  . THR A 1 27  ? -33.01724 -31.96388 5.67777   1.000 32.00378  ? 27  THR A CG2  1 
ATOM   375  H H    . THR A 1 27  ? -33.39335 -28.98817 6.10383   1.000 31.33091  ? 27  THR A H    1 
ATOM   376  H HA   . THR A 1 27  ? -32.04565 -29.33912 3.84148   1.000 35.93136  ? 27  THR A HA   1 
ATOM   377  H HB   . THR A 1 27  ? -31.23278 -31.19188 5.04115   1.000 36.17915  ? 27  THR A HB   1 
ATOM   378  H HG1  . THR A 1 27  ? -31.58787 -31.57501 2.90713   1.000 37.66742  ? 27  THR A HG1  1 
ATOM   379  H HG21 . THR A 1 27  ? -32.60048 -32.80333 5.92783   1.000 38.56307  ? 27  THR A HG21 1 
ATOM   380  H HG22 . THR A 1 27  ? -33.14575 -31.42645 6.47499   1.000 38.56307  ? 27  THR A HG22 1 
ATOM   381  H HG23 . THR A 1 27  ? -33.88231 -32.14822 5.27957   1.000 38.56307  ? 27  THR A HG23 1 
ATOM   382  N N    . SER A 1 28  ? -34.22337 -30.52126 2.80452   1.000 39.89365  ? 28  SER A N    1 
ATOM   383  C CA   . SER A 1 28  ? -35.52419 -30.70423 2.17703   1.000 26.93101  ? 28  SER A CA   1 
ATOM   384  C C    . SER A 1 28  ? -36.20679 -31.93504 2.75887   1.000 41.99999  ? 28  SER A C    1 
ATOM   385  O O    . SER A 1 28  ? -35.55894 -32.95242 3.02101   1.000 35.14389  ? 28  SER A O    1 
ATOM   386  C CB   . SER A 1 28  ? -35.36948 -30.85775 0.66243   1.000 30.49326  ? 28  SER A CB   1 
ATOM   387  O OG   . SER A 1 28  ? -36.59359 -31.21588 0.04786   1.000 39.03991  ? 28  SER A OG   1 
ATOM   388  H H    . SER A 1 28  ? -33.58814 -30.93668 2.40015   1.000 48.03092  ? 28  SER A H    1 
ATOM   389  H HA   . SER A 1 28  ? -36.08424 -29.93063 2.34674   1.000 32.47576  ? 28  SER A HA   1 
ATOM   390  H HB2  . SER A 1 28  ? -35.06842 -30.01354 0.29153   1.000 36.75046  ? 28  SER A HB2  1 
ATOM   391  H HB3  . SER A 1 28  ? -34.71500 -31.55096 0.48347   1.000 36.75046  ? 28  SER A HB3  1 
ATOM   392  H HG   . SER A 1 28  ? -36.70324 -32.04767 0.08914   1.000 47.00643  ? 28  SER A HG   1 
ATOM   393  N N    . THR A 1 29  ? -37.52365 -31.83310 2.95885   1.000 26.47912  ? 29  THR A N    1 
ATOM   394  C CA   . THR A 1 29  ? -38.27841 -32.95638 3.50954   1.000 30.08722  ? 29  THR A CA   1 
ATOM   395  C C    . THR A 1 29  ? -38.26608 -34.16101 2.57346   1.000 36.58202  ? 29  THR A C    1 
ATOM   396  O O    . THR A 1 29  ? -38.41643 -35.30082 3.02882   1.000 28.98631  ? 29  THR A O    1 
ATOM   397  C CB   . THR A 1 29  ? -39.71250 -32.51830 3.80594   1.000 31.46694  ? 29  THR A CB   1 
ATOM   398  O OG1  . THR A 1 29  ? -39.68879 -31.39316 4.69487   1.000 26.89423  ? 29  THR A OG1  1 
ATOM   399  C CG2  . THR A 1 29  ? -40.50971 -33.64301 4.44793   1.000 34.28702  ? 29  THR A CG2  1 
ATOM   400  H H    . THR A 1 29  ? -37.99541 -31.13504 2.78636   1.000 31.93348  ? 29  THR A H    1 
ATOM   401  H HA   . THR A 1 29  ? -37.86865 -33.23212 4.34438   1.000 36.26320  ? 29  THR A HA   1 
ATOM   402  H HB   . THR A 1 29  ? -40.15049 -32.27732 2.97468   1.000 37.91887  ? 29  THR A HB   1 
ATOM   403  H HG1  . THR A 1 29  ? -40.47073 -31.11829 4.83131   1.000 32.43161  ? 29  THR A HG1  1 
ATOM   404  H HG21 . THR A 1 29  ? -41.25060 -33.27665 4.95562   1.000 41.30296  ? 29  THR A HG21 1 
ATOM   405  H HG22 . THR A 1 29  ? -40.85925 -34.23462 3.76330   1.000 41.30296  ? 29  THR A HG22 1 
ATOM   406  H HG23 . THR A 1 29  ? -39.94101 -34.15386 5.04502   1.000 41.30296  ? 29  THR A HG23 1 
ATOM   407  N N    . HIS A 1 30  ? -38.07872 -33.93857 1.26743   1.000 34.22117  ? 30  HIS A N    1 
ATOM   408  C CA   . HIS A 1 30  ? -38.00730 -35.03542 0.30653   1.000 35.70651  ? 30  HIS A CA   1 
ATOM   409  C C    . HIS A 1 30  ? -36.65687 -35.73954 0.29867   1.000 37.31560  ? 30  HIS A C    1 
ATOM   410  O O    . HIS A 1 30  ? -36.53293 -36.80687 -0.31270  1.000 40.75094  ? 30  HIS A O    1 
ATOM   411  C CB   . HIS A 1 30  ? -38.30689 -34.51529 -1.10187  1.000 32.84474  ? 30  HIS A CB   1 
ATOM   412  C CG   . HIS A 1 30  ? -39.74658 -34.62723 -1.49155  1.000 45.16323  ? 30  HIS A CG   1 
ATOM   413  N ND1  . HIS A 1 30  ? -40.15176 -35.16520 -2.69367  1.000 39.39921  ? 30  HIS A ND1  1 
ATOM   414  C CD2  . HIS A 1 30  ? -40.87789 -34.28158 -0.83291  1.000 35.57559  ? 30  HIS A CD2  1 
ATOM   415  C CE1  . HIS A 1 30  ? -41.47092 -35.14121 -2.76160  1.000 49.78154  ? 30  HIS A CE1  1 
ATOM   416  N NE2  . HIS A 1 30  ? -41.93633 -34.61136 -1.64456  1.000 47.70683  ? 30  HIS A NE2  1 
ATOM   417  H H    . HIS A 1 30  ? -37.99034 -33.15868 0.91590   1.000 41.22394  ? 30  HIS A H    1 
ATOM   418  H HA   . HIS A 1 30  ? -38.68281 -35.69054 0.54189   1.000 43.00636  ? 30  HIS A HA   1 
ATOM   419  H HB2  . HIS A 1 30  ? -38.05973 -33.57842 -1.14754  1.000 39.57223  ? 30  HIS A HB2  1 
ATOM   420  H HB3  . HIS A 1 30  ? -37.78654 -35.02720 -1.74069  1.000 39.57223  ? 30  HIS A HB3  1 
ATOM   421  H HD2  . HIS A 1 30  ? -40.92897 -33.89365 0.01077   1.000 42.84925  ? 30  HIS A HD2  1 
ATOM   422  H HE1  . HIS A 1 30  ? -41.98458 -35.44559 -3.47462  1.000 59.89638  ? 30  HIS A HE1  1 
ATOM   423  H HE2  . HIS A 1 30  ? -42.76691 -34.49220 -1.45601  1.000 57.40674  ? 30  HIS A HE2  1 
ATOM   424  N N    . VAL A 1 31  ? -35.65868 -35.18412 0.97609   1.000 51.11845  ? 31  VAL A N    1 
ATOM   425  C CA   . VAL A 1 31  ? -34.28997 -35.68483 0.91385   1.000 39.83493  ? 31  VAL A CA   1 
ATOM   426  C C    . VAL A 1 31  ? -33.94205 -36.51072 2.14744   1.000 33.89429  ? 31  VAL A C    1 
ATOM   427  O O    . VAL A 1 31  ? -33.20166 -37.49898 2.04822   1.000 35.82418  ? 31  VAL A O    1 
ATOM   428  C CB   . VAL A 1 31  ? -33.32169 -34.49978 0.73295   1.000 32.89961  ? 31  VAL A CB   1 
ATOM   429  C CG1  . VAL A 1 31  ? -31.92808 -34.82262 1.23624   1.000 49.12499  ? 31  VAL A CG1  1 
ATOM   430  C CG2  . VAL A 1 31  ? -33.28720 -34.06609 -0.73543  1.000 36.99111  ? 31  VAL A CG2  1 
ATOM   431  H H    . VAL A 1 31  ? -35.74991 -34.50094 1.49043   1.000 61.50068  ? 31  VAL A H    1 
ATOM   432  H HA   . VAL A 1 31  ? -34.21080 -36.29262 0.16204   1.000 47.96046  ? 31  VAL A HA   1 
ATOM   433  H HB   . VAL A 1 31  ? -33.64668 -33.75902 1.26826   1.000 39.63807  ? 31  VAL A HB   1 
ATOM   434  H HG11 . VAL A 1 31  ? -31.34098 -34.07548 1.04135   1.000 59.10853  ? 31  VAL A HG11 1 
ATOM   435  H HG12 . VAL A 1 31  ? -31.96513 -34.97318 2.19377   1.000 59.10853  ? 31  VAL A HG12 1 
ATOM   436  H HG13 . VAL A 1 31  ? -31.60750 -35.62089 0.78804   1.000 59.10853  ? 31  VAL A HG13 1 
ATOM   437  H HG21 . VAL A 1 31  ? -32.69885 -33.30008 -0.82474  1.000 44.54787  ? 31  VAL A HG21 1 
ATOM   438  H HG22 . VAL A 1 31  ? -32.95656 -34.80174 -1.27431  1.000 44.54787  ? 31  VAL A HG22 1 
ATOM   439  H HG23 . VAL A 1 31  ? -34.18486 -33.82816 -1.01561  1.000 44.54787  ? 31  VAL A HG23 1 
ATOM   440  N N    . ILE A 1 32  ? -34.46920 -36.12527 3.30554   1.000 35.27868  ? 32  ILE A N    1 
ATOM   441  C CA   . ILE A 1 32  ? -33.98135 -36.69251 4.57355   1.000 28.28858  ? 32  ILE A CA   1 
ATOM   442  C C    . ILE A 1 32  ? -34.14081 -38.20788 4.55311   1.000 33.81726  ? 32  ILE A C    1 
ATOM   443  O O    . ILE A 1 32  ? -35.20984 -38.71270 4.15894   1.000 43.86649  ? 32  ILE A O    1 
ATOM   444  C CB   . ILE A 1 32  ? -34.73633 -36.06857 5.76158   1.000 36.87683  ? 32  ILE A CB   1 
ATOM   445  C CG1  . ILE A 1 32  ? -34.14400 -36.53977 7.09001   1.000 54.24986  ? 32  ILE A CG1  1 
ATOM   446  C CG2  . ILE A 1 32  ? -36.21762 -36.41197 5.70658   1.000 41.83841  ? 32  ILE A CG2  1 
ATOM   447  C CD1  . ILE A 1 32  ? -34.36737 -35.56669 8.22898   1.000 45.62678  ? 32  ILE A CD1  1 
ATOM   448  H H    . ILE A 1 32  ? -35.10000 -35.54709 3.39159   1.000 42.49296  ? 32  ILE A H    1 
ATOM   449  H HA   . ILE A 1 32  ? -33.03671 -36.49485 4.67100   1.000 34.10483  ? 32  ILE A HA   1 
ATOM   450  H HB   . ILE A 1 32  ? -34.63566 -35.10597 5.69699   1.000 44.41074  ? 32  ILE A HB   1 
ATOM   451  H HG12 . ILE A 1 32  ? -34.55572 -37.38330 7.33462   1.000 65.25837  ? 32  ILE A HG12 1 
ATOM   452  H HG13 . ILE A 1 32  ? -33.18712 -36.65659 6.98215   1.000 65.25837  ? 32  ILE A HG13 1 
ATOM   453  H HG21 . ILE A 1 32  ? -36.68646 -35.89699 6.38177   1.000 50.36463  ? 32  ILE A HG21 1 
ATOM   454  H HG22 . ILE A 1 32  ? -36.56021 -36.19245 4.82604   1.000 50.36463  ? 32  ILE A HG22 1 
ATOM   455  H HG23 . ILE A 1 32  ? -36.32851 -37.36030 5.87768   1.000 50.36463  ? 32  ILE A HG23 1 
ATOM   456  H HD11 . ILE A 1 32  ? -33.96203 -34.71541 8.00113   1.000 54.91068  ? 32  ILE A HD11 1 
ATOM   457  H HD12 . ILE A 1 32  ? -35.32107 -35.45312 8.36486   1.000 54.91068  ? 32  ILE A HD12 1 
ATOM   458  H HD13 . ILE A 1 32  ? -33.95874 -35.92288 9.03337   1.000 54.91068  ? 32  ILE A HD13 1 
ATOM   459  N N    . PRO A 1 33  ? -33.12321 -38.98038 4.94040   1.000 41.06408  ? 33  PRO A N    1 
ATOM   460  C CA   . PRO A 1 33  ? -33.28012 -40.44537 4.96166   1.000 30.70540  ? 33  PRO A CA   1 
ATOM   461  C C    . PRO A 1 33  ? -34.34517 -40.86182 5.96420   1.000 31.98782  ? 33  PRO A C    1 
ATOM   462  O O    . PRO A 1 33  ? -34.22016 -40.62380 7.16848   1.000 34.07132  ? 33  PRO A O    1 
ATOM   463  C CB   . PRO A 1 33  ? -31.88617 -40.94782 5.36124   1.000 37.40120  ? 33  PRO A CB   1 
ATOM   464  C CG   . PRO A 1 33  ? -30.95603 -39.81139 5.04992   1.000 50.87728  ? 33  PRO A CG   1 
ATOM   465  C CD   . PRO A 1 33  ? -31.75509 -38.56922 5.30829   1.000 39.68851  ? 33  PRO A CD   1 
ATOM   466  H HA   . PRO A 1 33  ? -33.50612 -40.78300 4.08085   1.000 37.00502  ? 33  PRO A HA   1 
ATOM   467  H HB2  . PRO A 1 33  ? -31.87076 -41.15906 6.30784   1.000 45.03998  ? 33  PRO A HB2  1 
ATOM   468  H HB3  . PRO A 1 33  ? -31.65806 -41.73472 4.84196   1.000 45.03998  ? 33  PRO A HB3  1 
ATOM   469  H HG2  . PRO A 1 33  ? -30.18035 -39.85110 5.63100   1.000 61.21127  ? 33  PRO A HG2  1 
ATOM   470  H HG3  . PRO A 1 33  ? -30.67795 -39.85727 4.12177   1.000 61.21127  ? 33  PRO A HG3  1 
ATOM   471  H HD2  . PRO A 1 33  ? -31.70849 -38.31436 6.24305   1.000 47.78476  ? 33  PRO A HD2  1 
ATOM   472  H HD3  . PRO A 1 33  ? -31.45014 -37.83747 4.74932   1.000 47.78476  ? 33  PRO A HD3  1 
ATOM   473  N N    . GLN A 1 34  ? -35.39791 -41.50228 5.45681   1.000 36.68497  ? 34  GLN A N    1 
ATOM   474  C CA   . GLN A 1 34  ? -36.57768 -41.75544 6.27256   1.000 33.92021  ? 34  GLN A CA   1 
ATOM   475  C C    . GLN A 1 34  ? -36.36472 -42.89001 7.26507   1.000 48.33519  ? 34  GLN A C    1 
ATOM   476  O O    . GLN A 1 34  ? -37.02682 -42.92580 8.30852   1.000 45.86132  ? 34  GLN A O    1 
ATOM   477  C CB   . GLN A 1 34  ? -37.77178 -42.07022 5.36888   1.000 36.01216  ? 34  GLN A CB   1 
ATOM   478  C CG   . GLN A 1 34  ? -39.11744 -41.72244 5.97820   1.000 61.46380  ? 34  GLN A CG   1 
ATOM   479  C CD   . GLN A 1 34  ? -39.42759 -40.23939 5.90371   1.000 47.62382  ? 34  GLN A CD   1 
ATOM   480  O OE1  . GLN A 1 34  ? -38.97646 -39.54220 4.99552   1.000 60.05569  ? 34  GLN A OE1  1 
ATOM   481  N NE2  . GLN A 1 34  ? -40.20443 -39.75080 6.86213   1.000 50.37924  ? 34  GLN A NE2  1 
ATOM   482  H H    . GLN A 1 34  ? -35.45164 -41.79682 4.65061   1.000 44.18050  ? 34  GLN A H    1 
ATOM   483  H HA   . GLN A 1 34  ? -36.78061 -40.95499 6.78147   1.000 40.86279  ? 34  GLN A HA   1 
ATOM   484  H HB2  . GLN A 1 34  ? -37.68085 -41.56405 4.54643   1.000 43.37313  ? 34  GLN A HB2  1 
ATOM   485  H HB3  . GLN A 1 34  ? -37.77264 -43.02067 5.17511   1.000 43.37313  ? 34  GLN A HB3  1 
ATOM   486  H HG2  . GLN A 1 34  ? -39.81392 -42.19922 5.50018   1.000 73.91510  ? 34  GLN A HG2  1 
ATOM   487  H HG3  . GLN A 1 34  ? -39.11845 -41.98284 6.91259   1.000 73.91510  ? 34  GLN A HG3  1 
ATOM   488  H HE21 . GLN A 1 34  ? -40.50239 -40.26922 7.48024   1.000 60.61362  ? 34  GLN A HE21 1 
ATOM   489  H HE22 . GLN A 1 34  ? -40.40995 -38.91572 6.86518   1.000 60.61362  ? 34  GLN A HE22 1 
ATOM   490  N N    . SER A 1 35  ? -35.44931 -43.81092 6.97155   1.000 46.48408  ? 35  SER A N    1 
ATOM   491  C CA   . SER A 1 35  ? -35.24382 -44.99612 7.79301   1.000 39.94341  ? 35  SER A CA   1 
ATOM   492  C C    . SER A 1 35  ? -33.90722 -44.96581 8.52970   1.000 34.21914  ? 35  SER A C    1 
ATOM   493  O O    . SER A 1 35  ? -33.32945 -46.01540 8.82074   1.000 55.66277  ? 35  SER A O    1 
ATOM   494  C CB   . SER A 1 35  ? -35.34817 -46.25574 6.93285   1.000 55.81613  ? 35  SER A CB   1 
ATOM   495  O OG   . SER A 1 35  ? -36.64922 -46.39341 6.38549   1.000 65.56721  ? 35  SER A OG   1 
ATOM   496  H H    . SER A 1 35  ? -34.92740 -43.76824 6.28935   1.000 55.93944  ? 35  SER A H    1 
ATOM   497  H HA   . SER A 1 35  ? -35.94159 -45.02613 8.46614   1.000 48.09063  ? 35  SER A HA   1 
ATOM   498  H HB2  . SER A 1 35  ? -34.70639 -46.19598 6.20797   1.000 67.13789  ? 35  SER A HB2  1 
ATOM   499  H HB3  . SER A 1 35  ? -35.15496 -47.03020 7.48401   1.000 67.13789  ? 35  SER A HB3  1 
ATOM   500  H HG   . SER A 1 35  ? -36.70440 -47.11130 5.95283   1.000 78.83919  ? 35  SER A HG   1 
ATOM   501  N N    . ALA A 1 36  ? -33.41362 -43.77462 8.85263   1.000 51.29384  ? 36  ALA A N    1 
ATOM   502  C CA   . ALA A 1 36  ? -32.14621 -43.63201 9.55286   1.000 47.91049  ? 36  ALA A CA   1 
ATOM   503  C C    . ALA A 1 36  ? -32.35261 -43.68937 11.05978  1.000 55.57124  ? 36  ALA A C    1 
ATOM   504  O O    . ALA A 1 36  ? -33.35058 -43.18442 11.58274  1.000 60.60408  ? 36  ALA A O    1 
ATOM   505  C CB   . ALA A 1 36  ? -31.46998 -42.31124 9.18041   1.000 41.08328  ? 36  ALA A CB   1 
ATOM   506  H H    . ALA A 1 36  ? -33.79967 -43.02710 8.67433   1.000 61.71115  ? 36  ALA A H    1 
ATOM   507  H HA   . ALA A 1 36  ? -31.56280 -44.36356 9.29717   1.000 57.65113  ? 36  ALA A HA   1 
ATOM   508  H HB1  . ALA A 1 36  ? -32.06115 -41.57767 9.41126   1.000 49.45848  ? 36  ALA A HB1  1 
ATOM   509  H HB2  . ALA A 1 36  ? -30.63775 -42.23279 9.67248   1.000 49.45848  ? 36  ALA A HB2  1 
ATOM   510  H HB3  . ALA A 1 36  ? -31.29226 -42.30534 8.22685   1.000 49.45848  ? 36  ALA A HB3  1 
ATOM   511  N N    . LYS A 1 37  ? -31.39528 -44.30622 11.75405  1.000 39.02865  ? 37  LYS A N    1 
ATOM   512  C CA   . LYS A 1 37  ? -31.35415 -44.30117 13.20993  1.000 53.18082  ? 37  LYS A CA   1 
ATOM   513  C C    . LYS A 1 37  ? -30.23387 -43.42329 13.75872  1.000 52.60894  ? 37  LYS A C    1 
ATOM   514  O O    . LYS A 1 37  ? -30.00857 -43.40876 14.97327  1.000 52.37928  ? 37  LYS A O    1 
ATOM   515  C CB   . LYS A 1 37  ? -31.19817 -45.72721 13.74346  1.000 59.03809  ? 37  LYS A CB   1 
ATOM   516  C CG   . LYS A 1 37  ? -32.44131 -46.58939 13.60291  1.000 51.57683  ? 37  LYS A CG   1 
ATOM   517  C CD   . LYS A 1 37  ? -32.39369 -47.77346 14.55896  1.000 73.31372  ? 37  LYS A CD   1 
ATOM   518  C CE   . LYS A 1 37  ? -33.60369 -48.68309 14.39174  1.000 75.90671  ? 37  LYS A CE   1 
ATOM   519  N NZ   . LYS A 1 37  ? -34.14679 -48.67390 13.00130  1.000 60.41220  ? 37  LYS A NZ   1 
ATOM   520  H H    . LYS A 1 37  ? -30.74740 -44.74204 11.39363  1.000 46.99292  ? 37  LYS A H    1 
ATOM   521  H HA   . LYS A 1 37  ? -32.19784 -43.94962 13.53473  1.000 63.97553  ? 37  LYS A HA   1 
ATOM   522  H HB2  . LYS A 1 37  ? -30.48199 -46.16330 13.25580  1.000 71.00425  ? 37  LYS A HB2  1 
ATOM   523  H HB3  . LYS A 1 37  ? -30.97756 -45.68206 14.68696  1.000 71.00425  ? 37  LYS A HB3  1 
ATOM   524  H HG2  . LYS A 1 37  ? -33.22728 -46.05961 13.80903  1.000 62.05074  ? 37  LYS A HG2  1 
ATOM   525  H HG3  . LYS A 1 37  ? -32.49854 -46.92893 12.69608  1.000 62.05074  ? 37  LYS A HG3  1 
ATOM   526  H HD2  . LYS A 1 37  ? -31.59496 -48.29507 14.38331  1.000 88.13501  ? 37  LYS A HD2  1 
ATOM   527  H HD3  . LYS A 1 37  ? -32.38275 -47.44736 15.47244  1.000 88.13501  ? 37  LYS A HD3  1 
ATOM   528  H HE2  . LYS A 1 37  ? -33.34699 -49.59340 14.60701  1.000 91.24660  ? 37  LYS A HE2  1 
ATOM   529  H HE3  . LYS A 1 37  ? -34.30723 -48.38648 14.99004  1.000 91.24660  ? 37  LYS A HE3  1 
ATOM   530  H HZ1  . LYS A 1 37  ? -34.76426 -49.30854 12.91149  1.000 72.65318  ? 37  LYS A HZ1  1 
ATOM   531  H HZ2  . LYS A 1 37  ? -34.51659 -47.88399 12.82416  1.000 72.65318  ? 37  LYS A HZ2  1 
ATOM   532  H HZ3  . LYS A 1 37  ? -33.49176 -48.82357 12.41766  1.000 72.65318  ? 37  LYS A HZ3  1 
ATOM   533  N N    . GLU A 1 38  ? -29.53389 -42.68495 12.90024  1.000 37.32303  ? 38  GLU A N    1 
ATOM   534  C CA   . GLU A 1 38  ? -28.38212 -41.90217 13.32890  1.000 48.19848  ? 38  GLU A CA   1 
ATOM   535  C C    . GLU A 1 38  ? -28.07628 -40.85608 12.26814  1.000 42.32684  ? 38  GLU A C    1 
ATOM   536  O O    . GLU A 1 38  ? -28.22753 -41.11467 11.07226  1.000 44.10327  ? 38  GLU A O    1 
ATOM   537  C CB   . GLU A 1 38  ? -27.16564 -42.81207 13.56534  1.000 45.46796  ? 38  GLU A CB   1 
ATOM   538  C CG   . GLU A 1 38  ? -25.83150 -42.09682 13.76315  1.000 68.73102  ? 38  GLU A CG   1 
ATOM   539  C CD   . GLU A 1 38  ? -24.68382 -42.82279 13.08137  1.000 62.07722  ? 38  GLU A CD   1 
ATOM   540  O OE1  . GLU A 1 38  ? -24.62568 -42.79037 11.83337  1.000 63.18467  ? 38  GLU A OE1  1 
ATOM   541  O OE2  . GLU A 1 38  ? -23.85355 -43.43278 13.78914  1.000 60.81510  ? 38  GLU A OE2  1 
ATOM   542  H H    . GLU A 1 38  ? -29.70810 -42.62148 12.06047  1.000 44.94618  ? 38  GLU A H    1 
ATOM   543  H HA   . GLU A 1 38  ? -28.58359 -41.43642 14.15558  1.000 57.99672  ? 38  GLU A HA   1 
ATOM   544  H HB2  . GLU A 1 38  ? -27.33051 -43.33912 14.36279  1.000 54.72010  ? 38  GLU A HB2  1 
ATOM   545  H HB3  . GLU A 1 38  ? -27.06813 -43.39534 12.79645  1.000 54.72010  ? 38  GLU A HB3  1 
ATOM   546  H HG2  . GLU A 1 38  ? -25.89019 -41.20436 13.38767  1.000 82.63577  ? 38  GLU A HG2  1 
ATOM   547  H HG3  . GLU A 1 38  ? -25.63561 -42.04541 14.71177  1.000 82.63577  ? 38  GLU A HG3  1 
ATOM   548  N N    . PHE A 1 39  ? -27.65222 -39.67615 12.71951  1.000 36.48341  ? 39  PHE A N    1 
ATOM   549  C CA   . PHE A 1 39  ? -27.16649 -38.62239 11.83436  1.000 50.85094  ? 39  PHE A CA   1 
ATOM   550  C C    . PHE A 1 39  ? -25.89262 -38.05214 12.43931  1.000 31.52110  ? 39  PHE A C    1 
ATOM   551  O O    . PHE A 1 39  ? -25.90070 -37.60061 13.58891  1.000 43.78856  ? 39  PHE A O    1 
ATOM   552  C CB   . PHE A 1 39  ? -28.20940 -37.51711 11.63996  1.000 39.90679  ? 39  PHE A CB   1 
ATOM   553  C CG   . PHE A 1 39  ? -29.34203 -37.90276 10.72743  1.000 44.70220  ? 39  PHE A CG   1 
ATOM   554  C CD1  . PHE A 1 39  ? -29.09871 -38.57804 9.54235   1.000 42.57399  ? 39  PHE A CD1  1 
ATOM   555  C CD2  . PHE A 1 39  ? -30.65155 -37.59115 11.05543  1.000 37.36292  ? 39  PHE A CD2  1 
ATOM   556  C CE1  . PHE A 1 39  ? -30.13719 -38.93482 8.70281   1.000 50.07149  ? 39  PHE A CE1  1 
ATOM   557  C CE2  . PHE A 1 39  ? -31.69582 -37.94924 10.21910  1.000 31.40100  ? 39  PHE A CE2  1 
ATOM   558  C CZ   . PHE A 1 39  ? -31.43750 -38.62137 9.04213   1.000 37.47538  ? 39  PHE A CZ   1 
ATOM   559  H H    . PHE A 1 39  ? -27.63646 -39.45915 13.55154  1.000 43.93863  ? 39  PHE A H    1 
ATOM   560  H HA   . PHE A 1 39  ? -26.96549 -38.99818 10.96299  1.000 61.17966  ? 39  PHE A HA   1 
ATOM   561  H HB2  . PHE A 1 39  ? -28.58918 -37.29181 12.50361  1.000 48.04669  ? 39  PHE A HB2  1 
ATOM   562  H HB3  . PHE A 1 39  ? -27.77245 -36.74044 11.25688  1.000 48.04669  ? 39  PHE A HB3  1 
ATOM   563  H HD1  . PHE A 1 39  ? -28.22490 -38.79418 9.30860   1.000 51.24733  ? 39  PHE A HD1  1 
ATOM   564  H HD2  . PHE A 1 39  ? -30.83144 -37.13624 11.84638  1.000 44.99404  ? 39  PHE A HD2  1 
ATOM   565  H HE1  . PHE A 1 39  ? -29.95957 -39.38611 7.90928   1.000 60.24433  ? 39  PHE A HE1  1 
ATOM   566  H HE2  . PHE A 1 39  ? -32.57105 -37.73668 10.45079  1.000 37.83974  ? 39  PHE A HE2  1 
ATOM   567  H HZ   . PHE A 1 39  ? -32.13751 -38.86240 8.47929   1.000 45.12900  ? 39  PHE A HZ   1 
ATOM   568  N N    . PHE A 1 40  ? -24.80302 -38.08377 11.67203  1.000 42.10417  ? 40  PHE A N    1 
ATOM   569  C CA   . PHE A 1 40  ? -23.51128 -37.56949 12.12472  1.000 35.79300  ? 40  PHE A CA   1 
ATOM   570  C C    . PHE A 1 40  ? -23.11422 -38.18579 13.46204  1.000 37.57746  ? 40  PHE A C    1 
ATOM   571  O O    . PHE A 1 40  ? -22.54573 -37.52589 14.33471  1.000 43.66909  ? 40  PHE A O    1 
ATOM   572  C CB   . PHE A 1 40  ? -23.54075 -36.04507 12.20707  1.000 35.81012  ? 40  PHE A CB   1 
ATOM   573  C CG   . PHE A 1 40  ? -24.05247 -35.39447 10.96048  1.000 43.88452  ? 40  PHE A CG   1 
ATOM   574  C CD1  . PHE A 1 40  ? -23.40255 -35.58977 9.75284   1.000 34.48967  ? 40  PHE A CD1  1 
ATOM   575  C CD2  . PHE A 1 40  ? -25.18630 -34.60088 10.98805  1.000 40.27999  ? 40  PHE A CD2  1 
ATOM   576  C CE1  . PHE A 1 40  ? -23.86857 -35.00264 8.59778   1.000 36.46173  ? 40  PHE A CE1  1 
ATOM   577  C CE2  . PHE A 1 40  ? -25.65851 -34.00877 9.83478   1.000 31.30380  ? 40  PHE A CE2  1 
ATOM   578  C CZ   . PHE A 1 40  ? -24.99790 -34.20925 8.63730   1.000 34.57471  ? 40  PHE A CZ   1 
ATOM   579  H H    . PHE A 1 40  ? -24.78630 -38.40288 10.87360  1.000 50.68354  ? 40  PHE A H    1 
ATOM   580  H HA   . PHE A 1 40  ? -22.83217 -37.82246 11.47995  1.000 43.11014  ? 40  PHE A HA   1 
ATOM   581  H HB2  . PHE A 1 40  ? -24.11939 -35.78172 12.93968  1.000 43.13068  ? 40  PHE A HB2  1 
ATOM   582  H HB3  . PHE A 1 40  ? -22.63961 -35.72198 12.36342  1.000 43.13068  ? 40  PHE A HB3  1 
ATOM   583  H HD1  . PHE A 1 40  ? -22.64199 -36.12408 9.72182   1.000 41.54614  ? 40  PHE A HD1  1 
ATOM   584  H HD2  . PHE A 1 40  ? -25.63415 -34.46550 11.79180  1.000 48.49453  ? 40  PHE A HD2  1 
ATOM   585  H HE1  . PHE A 1 40  ? -23.42362 -35.14019 7.79280   1.000 43.91261  ? 40  PHE A HE1  1 
ATOM   586  H HE2  . PHE A 1 40  ? -26.42001 -33.47566 9.86307   1.000 37.72310  ? 40  PHE A HE2  1 
ATOM   587  H HZ   . PHE A 1 40  ? -25.31380 -33.81012 7.85897   1.000 41.64820  ? 40  PHE A HZ   1 
ATOM   588  N N    . GLY A 1 41  ? -23.42170 -39.47248 13.62087  1.000 51.30548  ? 41  GLY A N    1 
ATOM   589  C CA   . GLY A 1 41  ? -23.09679 -40.20343 14.82417  1.000 41.17606  ? 41  GLY A CA   1 
ATOM   590  C C    . GLY A 1 41  ? -24.06742 -40.04015 15.97292  1.000 45.19901  ? 41  GLY A C    1 
ATOM   591  O O    . GLY A 1 41  ? -23.92618 -40.74467 16.98124  1.000 43.71784  ? 41  GLY A O    1 
ATOM   592  H H    . GLY A 1 41  ? -23.82702 -39.94647 13.02871  1.000 61.72512  ? 41  GLY A H    1 
ATOM   593  H HA2  . GLY A 1 41  ? -23.05587 -41.14818 14.60814  1.000 49.56981  ? 41  GLY A HA2  1 
ATOM   594  H HA3  . GLY A 1 41  ? -22.22506 -39.91239 15.13448  1.000 49.56981  ? 41  GLY A HA3  1 
ATOM   595  N N    . VAL A 1 42  ? -25.04613 -39.14646 15.86489  1.000 46.20726  ? 42  VAL A N    1 
ATOM   596  C CA   . VAL A 1 42  ? -25.98245 -38.89291 16.95786  1.000 37.43518  ? 42  VAL A CA   1 
ATOM   597  C C    . VAL A 1 42  ? -27.19824 -39.80176 16.81475  1.000 46.80854  ? 42  VAL A C    1 
ATOM   598  O O    . VAL A 1 42  ? -27.78313 -39.87477 15.72464  1.000 36.10364  ? 42  VAL A O    1 
ATOM   599  C CB   . VAL A 1 42  ? -26.42183 -37.41796 16.98616  1.000 46.33043  ? 42  VAL A CB   1 
ATOM   600  C CG1  . VAL A 1 42  ? -27.33127 -37.15913 18.18335  1.000 45.19501  ? 42  VAL A CG1  1 
ATOM   601  C CG2  . VAL A 1 42  ? -25.21763 -36.48879 17.00492  1.000 51.22232  ? 42  VAL A CG2  1 
ATOM   602  H H    . VAL A 1 42  ? -25.19052 -38.67006 15.16361  1.000 55.60725  ? 42  VAL A H    1 
ATOM   603  H HA   . VAL A 1 42  ? -25.53621 -39.10800 17.79183  1.000 45.08076  ? 42  VAL A HA   1 
ATOM   604  H HB   . VAL A 1 42  ? -26.92308 -37.22672 16.17803  1.000 55.75506  ? 42  VAL A HB   1 
ATOM   605  H HG11 . VAL A 1 42  ? -27.43567 -36.20179 18.29949  1.000 54.39255  ? 42  VAL A HG11 1 
ATOM   606  H HG12 . VAL A 1 42  ? -28.19503 -37.56843 18.01811  1.000 54.39255  ? 42  VAL A HG12 1 
ATOM   607  H HG13 . VAL A 1 42  ? -26.92790 -37.54644 18.97593  1.000 54.39255  ? 42  VAL A HG13 1 
ATOM   608  H HG21 . VAL A 1 42  ? -25.52624 -35.57369 17.09571  1.000 61.62533  ? 42  VAL A HG21 1 
ATOM   609  H HG22 . VAL A 1 42  ? -24.65007 -36.72252 17.75601  1.000 61.62533  ? 42  VAL A HG22 1 
ATOM   610  H HG23 . VAL A 1 42  ? -24.72658 -36.59145 16.17472  1.000 61.62533  ? 42  VAL A HG23 1 
ATOM   611  N N    . PRO A 1 43  ? -27.62207 -40.50025 17.86966  1.000 51.89290  ? 43  PRO A N    1 
ATOM   612  C CA   . PRO A 1 43  ? -28.87473 -41.26629 17.78175  1.000 49.81529  ? 43  PRO A CA   1 
ATOM   613  C C    . PRO A 1 43  ? -30.05082 -40.34987 17.47260  1.000 44.45259  ? 43  PRO A C    1 
ATOM   614  O O    . PRO A 1 43  ? -30.20737 -39.28527 18.07507  1.000 48.26386  ? 43  PRO A O    1 
ATOM   615  C CB   . PRO A 1 43  ? -29.00074 -41.91095 19.16817  1.000 41.73950  ? 43  PRO A CB   1 
ATOM   616  C CG   . PRO A 1 43  ? -27.60622 -41.93498 19.70890  1.000 51.43850  ? 43  PRO A CG   1 
ATOM   617  C CD   . PRO A 1 43  ? -26.94483 -40.69818 19.16619  1.000 53.87386  ? 43  PRO A CD   1 
ATOM   618  H HA   . PRO A 1 43  ? -28.81008 -41.96030 17.10716  1.000 59.93689  ? 43  PRO A HA   1 
ATOM   619  H HB2  . PRO A 1 43  ? -29.58225 -41.37536 19.73020  1.000 49.29469  ? 43  PRO A HB2  1 
ATOM   620  H HB3  . PRO A 1 43  ? -29.35636 -42.80947 19.08390  1.000 49.29469  ? 43  PRO A HB3  1 
ATOM   621  H HG2  . PRO A 1 43  ? -27.62914 -41.91681 20.67846  1.000 61.88475  ? 43  PRO A HG2  1 
ATOM   622  H HG3  . PRO A 1 43  ? -27.14857 -42.73357 19.40278  1.000 61.88475  ? 43  PRO A HG3  1 
ATOM   623  H HD2  . PRO A 1 43  ? -27.09283 -39.94040 19.75335  1.000 64.80717  ? 43  PRO A HD2  1 
ATOM   624  H HD3  . PRO A 1 43  ? -25.99346 -40.84057 19.04168  1.000 64.80717  ? 43  PRO A HD3  1 
ATOM   625  N N    . ILE A 1 44  ? -30.88524 -40.77856 16.52200  1.000 55.14226  ? 44  ILE A N    1 
ATOM   626  C CA   . ILE A 1 44  ? -31.96617 -39.92778 16.02959  1.000 46.22185  ? 44  ILE A CA   1 
ATOM   627  C C    . ILE A 1 44  ? -32.93900 -39.56821 17.14490  1.000 38.82599  ? 44  ILE A C    1 
ATOM   628  O O    . ILE A 1 44  ? -33.56184 -38.50004 17.11326  1.000 47.01648  ? 44  ILE A O    1 
ATOM   629  C CB   . ILE A 1 44  ? -32.67775 -40.62642 14.85365  1.000 54.29306  ? 44  ILE A CB   1 
ATOM   630  C CG1  . ILE A 1 44  ? -33.59293 -39.64993 14.11552  1.000 37.26789  ? 44  ILE A CG1  1 
ATOM   631  C CG2  . ILE A 1 44  ? -33.48088 -41.82569 15.34791  1.000 48.41883  ? 44  ILE A CG2  1 
ATOM   632  C CD1  . ILE A 1 44  ? -32.86555 -38.49648 13.48467  1.000 44.95094  ? 44  ILE A CD1  1 
ATOM   633  H H    . ILE A 1 44  ? -30.84636 -41.55250 16.14904  1.000 66.32926  ? 44  ILE A H    1 
ATOM   634  H HA   . ILE A 1 44  ? -31.58419 -39.09654 15.70706  1.000 55.62476  ? 44  ILE A HA   1 
ATOM   635  H HB   . ILE A 1 44  ? -31.99655 -40.93751 14.23715  1.000 65.31021  ? 44  ILE A HB   1 
ATOM   636  H HG12 . ILE A 1 44  ? -34.05604 -40.12892 13.41053  1.000 44.88001  ? 44  ILE A HG12 1 
ATOM   637  H HG13 . ILE A 1 44  ? -34.23406 -39.28623 14.74605  1.000 44.88001  ? 44  ILE A HG13 1 
ATOM   638  H HG21 . ILE A 1 44  ? -33.72738 -42.37561 14.58783  1.000 58.26114  ? 44  ILE A HG21 1 
ATOM   639  H HG22 . ILE A 1 44  ? -32.93526 -42.33877 15.96431  1.000 58.26114  ? 44  ILE A HG22 1 
ATOM   640  H HG23 . ILE A 1 44  ? -34.27872 -41.50742 15.79853  1.000 58.26114  ? 44  ILE A HG23 1 
ATOM   641  H HD11 . ILE A 1 44  ? -33.31208 -38.25571 12.65791  1.000 54.09967  ? 44  ILE A HD11 1 
ATOM   642  H HD12 . ILE A 1 44  ? -32.87507 -37.74423 14.09698  1.000 54.09967  ? 44  ILE A HD12 1 
ATOM   643  H HD13 . ILE A 1 44  ? -31.95084 -38.76221 13.30134  1.000 54.09967  ? 44  ILE A HD13 1 
ATOM   644  N N    . LYS A 1 45  ? -33.09260 -40.43998 18.14369  1.000 47.18263  ? 45  LYS A N    1 
ATOM   645  C CA   . LYS A 1 45  ? -33.94000 -40.09946 19.28277  1.000 49.81607  ? 45  LYS A CA   1 
ATOM   646  C C    . LYS A 1 45  ? -33.45959 -38.82394 19.96610  1.000 56.91991  ? 45  LYS A C    1 
ATOM   647  O O    . LYS A 1 45  ? -34.26605 -38.08691 20.54490  1.000 52.37267  ? 45  LYS A O    1 
ATOM   648  C CB   . LYS A 1 45  ? -33.96991 -41.26184 20.27711  1.000 50.33555  ? 45  LYS A CB   1 
ATOM   649  C CG   . LYS A 1 45  ? -34.93313 -41.07647 21.44551  1.000 77.58075  ? 45  LYS A CG   1 
ATOM   650  C CD   . LYS A 1 45  ? -36.30074 -41.68330 21.15558  1.000 90.02822  ? 45  LYS A CD   1 
ATOM   651  C CE   . LYS A 1 45  ? -37.38628 -41.05569 22.02079  1.000 81.11793  ? 45  LYS A CE   1 
ATOM   652  N NZ   . LYS A 1 45  ? -37.60093 -39.61948 21.67710  1.000 75.16413  ? 45  LYS A NZ   1 
ATOM   653  H H    . LYS A 1 45  ? -32.72544 -41.21661 18.18412  1.000 56.77770  ? 45  LYS A H    1 
ATOM   654  H HA   . LYS A 1 45  ? -34.84669 -39.95102 18.97167  1.000 59.93783  ? 45  LYS A HA   1 
ATOM   655  H HB2  . LYS A 1 45  ? -34.23613 -42.06553 19.80372  1.000 60.56121  ? 45  LYS A HB2  1 
ATOM   656  H HB3  . LYS A 1 45  ? -33.08021 -41.37397 20.64693  1.000 60.56121  ? 45  LYS A HB3  1 
ATOM   657  H HG2  . LYS A 1 45  ? -34.56900 -41.51137 22.23238  1.000 93.25544  ? 45  LYS A HG2  1 
ATOM   658  H HG3  . LYS A 1 45  ? -35.05162 -40.12879 21.61516  1.000 93.25544  ? 45  LYS A HG3  1 
ATOM   659  H HD2  . LYS A 1 45  ? -36.52807 -41.53266 20.22471  1.000 108.19241 ? 45  LYS A HD2  1 
ATOM   660  H HD3  . LYS A 1 45  ? -36.27560 -42.63505 21.34113  1.000 108.19241 ? 45  LYS A HD3  1 
ATOM   661  H HE2  . LYS A 1 45  ? -38.22097 -41.53006 21.88236  1.000 97.50006  ? 45  LYS A HE2  1 
ATOM   662  H HE3  . LYS A 1 45  ? -37.12455 -41.10992 22.95324  1.000 97.50006  ? 45  LYS A HE3  1 
ATOM   663  H HZ1  . LYS A 1 45  ? -36.88492 -39.14194 21.90377  1.000 90.35549  ? 45  LYS A HZ1  1 
ATOM   664  H HZ2  . LYS A 1 45  ? -37.74044 -39.53339 20.80233  1.000 90.35549  ? 45  LYS A HZ2  1 
ATOM   665  H HZ3  . LYS A 1 45  ? -38.30879 -39.30423 22.11488  1.000 90.35549  ? 45  LYS A HZ3  1 
ATOM   666  N N    . GLN A 1 46  ? -32.15610 -38.54535 19.90357  1.000 58.50212  ? 46  GLN A N    1 
ATOM   667  C CA   . GLN A 1 46  ? -31.58383 -37.35432 20.51471  1.000 50.95497  ? 46  GLN A CA   1 
ATOM   668  C C    . GLN A 1 46  ? -31.74597 -36.10309 19.66352  1.000 47.26398  ? 46  GLN A C    1 
ATOM   669  O O    . GLN A 1 46  ? -31.47140 -35.00319 20.15561  1.000 48.88219  ? 46  GLN A O    1 
ATOM   670  C CB   . GLN A 1 46  ? -30.09160 -37.56435 20.77595  1.000 50.10920  ? 46  GLN A CB   1 
ATOM   671  C CG   . GLN A 1 46  ? -29.77097 -38.69486 21.71853  1.000 57.10995  ? 46  GLN A CG   1 
ATOM   672  C CD   . GLN A 1 46  ? -29.27362 -38.19659 23.05505  1.000 82.73484  ? 46  GLN A CD   1 
ATOM   673  O OE1  . GLN A 1 46  ? -29.79602 -37.22405 23.60147  1.000 86.94401  ? 46  GLN A OE1  1 
ATOM   674  N NE2  . GLN A 1 46  ? -28.24904 -38.85225 23.58598  1.000 76.94621  ? 46  GLN A NE2  1 
ATOM   675  H H    . GLN A 1 46  ? -31.57632 -39.04056 19.50581  1.000 70.36109  ? 46  GLN A H    1 
ATOM   676  H HA   . GLN A 1 46  ? -32.03474 -37.20889 21.36113  1.000 61.30450  ? 46  GLN A HA   1 
ATOM   677  H HB2  . GLN A 1 46  ? -29.65474 -37.75541 19.93124  1.000 60.28958  ? 46  GLN A HB2  1 
ATOM   678  H HB3  . GLN A 1 46  ? -29.72865 -36.75126 21.16073  1.000 60.28958  ? 46  GLN A HB3  1 
ATOM   679  H HG2  . GLN A 1 46  ? -30.57219 -39.22013 21.87034  1.000 68.69048  ? 46  GLN A HG2  1 
ATOM   680  H HG3  . GLN A 1 46  ? -29.07942 -39.25047 21.32616  1.000 68.69048  ? 46  GLN A HG3  1 
ATOM   681  H HE21 . GLN A 1 46  ? -27.90511 -39.52191 23.17022  1.000 92.49399  ? 46  GLN A HE21 1 
ATOM   682  H HE22 . GLN A 1 46  ? -27.92907 -38.60742 24.34577  1.000 92.49399  ? 46  GLN A HE22 1 
ATOM   683  N N    . ILE A 1 47  ? -32.16134 -36.24348 18.40818  1.000 46.05132  ? 47  ILE A N    1 
ATOM   684  C CA   . ILE A 1 47  ? -32.24393 -35.13451 17.46402  1.000 31.91502  ? 47  ILE A CA   1 
ATOM   685  C C    . ILE A 1 47  ? -33.68530 -34.64696 17.41589  1.000 41.54654  ? 47  ILE A C    1 
ATOM   686  O O    . ILE A 1 47  ? -34.61609 -35.45012 17.27309  1.000 50.69266  ? 47  ILE A O    1 
ATOM   687  C CB   . ILE A 1 47  ? -31.75998 -35.56451 16.06725  1.000 34.54551  ? 47  ILE A CB   1 
ATOM   688  C CG1  . ILE A 1 47  ? -30.32837 -36.10761 16.13828  1.000 37.33897  ? 47  ILE A CG1  1 
ATOM   689  C CG2  . ILE A 1 47  ? -31.83667 -34.40485 15.08041  1.000 34.33400  ? 47  ILE A CG2  1 
ATOM   690  C CD1  . ILE A 1 47  ? -29.86993 -36.80629 14.86358  1.000 40.14815  ? 47  ILE A CD1  1 
ATOM   691  H H    . ILE A 1 47  ? -32.40814 -36.99485 18.07035  1.000 55.42013  ? 47  ILE A H    1 
ATOM   692  H HA   . ILE A 1 47  ? -31.68540 -34.40390 17.77249  1.000 37.50532  ? 47  ILE A HA   1 
ATOM   693  H HB   . ILE A 1 47  ? -32.34694 -36.27075 15.75485  1.000 41.61315  ? 47  ILE A HB   1 
ATOM   694  H HG12 . ILE A 1 47  ? -29.72269 -35.36837 16.30436  1.000 44.96531  ? 47  ILE A HG12 1 
ATOM   695  H HG13 . ILE A 1 47  ? -30.27452 -36.74991 16.86315  1.000 44.96531  ? 47  ILE A HG13 1 
ATOM   696  H HG21 . ILE A 1 47  ? -31.43776 -34.67869 14.23971  1.000 41.35935  ? 47  ILE A HG21 1 
ATOM   697  H HG22 . ILE A 1 47  ? -32.76723 -34.16786 14.94332  1.000 41.35935  ? 47  ILE A HG22 1 
ATOM   698  H HG23 . ILE A 1 47  ? -31.35268 -33.64740 15.44499  1.000 41.35935  ? 47  ILE A HG23 1 
ATOM   699  H HD11 . ILE A 1 47  ? -29.04612 -37.28525 15.04478  1.000 48.33632  ? 47  ILE A HD11 1 
ATOM   700  H HD12 . ILE A 1 47  ? -30.55818 -37.42780 14.57911  1.000 48.33632  ? 47  ILE A HD12 1 
ATOM   701  H HD13 . ILE A 1 47  ? -29.72054 -36.14009 14.17455  1.000 48.33632  ? 47  ILE A HD13 1 
ATOM   702  N N    . GLN A 1 48  ? -33.87126 -33.33189 17.52832  1.000 49.04604  ? 48  GLN A N    1 
ATOM   703  C CA   . GLN A 1 48  ? -35.19212 -32.71001 17.50279  1.000 34.29477  ? 48  GLN A CA   1 
ATOM   704  C C    . GLN A 1 48  ? -35.47430 -32.23980 16.08071  1.000 41.98861  ? 48  GLN A C    1 
ATOM   705  O O    . GLN A 1 48  ? -34.85020 -31.28901 15.59960  1.000 35.45204  ? 48  GLN A O    1 
ATOM   706  C CB   . GLN A 1 48  ? -35.25934 -31.54935 18.49286  1.000 41.74599  ? 48  GLN A CB   1 
ATOM   707  C CG   . GLN A 1 48  ? -34.65325 -31.86984 19.85200  1.000 64.75757  ? 48  GLN A CG   1 
ATOM   708  C CD   . GLN A 1 48  ? -35.30428 -31.09593 20.98114  1.000 71.29791  ? 48  GLN A CD   1 
ATOM   709  O OE1  . GLN A 1 48  ? -35.19916 -29.87232 21.05466  1.000 84.06647  ? 48  GLN A OE1  1 
ATOM   710  N NE2  . GLN A 1 48  ? -35.98999 -31.81025 21.86712  1.000 75.78306  ? 48  GLN A NE2  1 
ATOM   711  H H    . GLN A 1 48  ? -33.23039 -32.76621 17.62270  1.000 59.01378  ? 48  GLN A H    1 
ATOM   712  H HA   . GLN A 1 48  ? -35.86562 -33.36285 17.74998  1.000 41.31227  ? 48  GLN A HA   1 
ATOM   713  H HB2  . GLN A 1 48  ? -34.77504 -30.79483 18.12267  1.000 50.25373  ? 48  GLN A HB2  1 
ATOM   714  H HB3  . GLN A 1 48  ? -36.18927 -31.31088 18.63164  1.000 50.25373  ? 48  GLN A HB3  1 
ATOM   715  H HG2  . GLN A 1 48  ? -34.76562 -32.81614 20.03308  1.000 77.86762  ? 48  GLN A HG2  1 
ATOM   716  H HG3  . GLN A 1 48  ? -33.70992 -31.64435 19.83861  1.000 77.86762  ? 48  GLN A HG3  1 
ATOM   717  H HE21 . GLN A 1 48  ? -36.04533 -32.66411 21.78073  1.000 91.09821  ? 48  GLN A HE21 1 
ATOM   718  H HE22 . GLN A 1 48  ? -36.37848 -31.41875 22.52697  1.000 91.09821  ? 48  GLN A HE22 1 
ATOM   719  N N    . ILE A 1 49  ? -36.41061 -32.90286 15.40813  1.000 28.49977  ? 49  ILE A N    1 
ATOM   720  C CA   . ILE A 1 49  ? -36.69689 -32.64525 14.00204  1.000 30.05149  ? 49  ILE A CA   1 
ATOM   721  C C    . ILE A 1 49  ? -38.06851 -31.99662 13.89181  1.000 39.79021  ? 49  ILE A C    1 
ATOM   722  O O    . ILE A 1 49  ? -39.05611 -32.51291 14.42856  1.000 28.29083  ? 49  ILE A O    1 
ATOM   723  C CB   . ILE A 1 49  ? -36.61868 -33.93423 13.16320  1.000 34.84979  ? 49  ILE A CB   1 
ATOM   724  C CG1  . ILE A 1 49  ? -35.29081 -34.64883 13.44274  1.000 26.18219  ? 49  ILE A CG1  1 
ATOM   725  C CG2  . ILE A 1 49  ? -36.76689 -33.60667 11.68405  1.000 34.78887  ? 49  ILE A CG2  1 
ATOM   726  C CD1  . ILE A 1 49  ? -34.89992 -35.68894 12.41524  1.000 32.19806  ? 49  ILE A CD1  1 
ATOM   727  H H    . ILE A 1 49  ? -36.90209 -33.51856 15.75305  1.000 33.40702  ? 49  ILE A H    1 
ATOM   728  H HA   . ILE A 1 49  ? -36.04276 -32.01817 13.65594  1.000 36.22032  ? 49  ILE A HA   1 
ATOM   729  H HB   . ILE A 1 49  ? -37.34532 -34.52605 13.41348  1.000 41.97829  ? 49  ILE A HB   1 
ATOM   730  H HG12 . ILE A 1 49  ? -34.58386 -33.98518 13.46909  1.000 30.62592  ? 49  ILE A HG12 1 
ATOM   731  H HG13 . ILE A 1 49  ? -35.35723 -35.09704 14.30040  1.000 30.62592  ? 49  ILE A HG13 1 
ATOM   732  H HG21 . ILE A 1 49  ? -36.86182 -34.43331 11.18551  1.000 41.90518  ? 49  ILE A HG21 1 
ATOM   733  H HG22 . ILE A 1 49  ? -37.55409 -33.05356 11.56042  1.000 41.90518  ? 49  ILE A HG22 1 
ATOM   734  H HG23 . ILE A 1 49  ? -35.97699 -33.12926 11.38563  1.000 41.90518  ? 49  ILE A HG23 1 
ATOM   735  H HD11 . ILE A 1 49  ? -34.13054 -36.18147 12.74137  1.000 38.79621  ? 49  ILE A HD11 1 
ATOM   736  H HD12 . ILE A 1 49  ? -35.64597 -36.29356 12.27832  1.000 38.79621  ? 49  ILE A HD12 1 
ATOM   737  H HD13 . ILE A 1 49  ? -34.67855 -35.24291 11.58280  1.000 38.79621  ? 49  ILE A HD13 1 
ATOM   738  N N    . HIS A 1 50  ? -38.12153 -30.86049 13.20308  1.000 33.42075  ? 50  HIS A N    1 
ATOM   739  C CA   . HIS A 1 50  ? -39.35798 -30.14770 12.91736  1.000 44.18377  ? 50  HIS A CA   1 
ATOM   740  C C    . HIS A 1 50  ? -39.51059 -30.04896 11.40636  1.000 41.63459  ? 50  HIS A C    1 
ATOM   741  O O    . HIS A 1 50  ? -38.53197 -29.81268 10.68983  1.000 40.30178  ? 50  HIS A O    1 
ATOM   742  C CB   . HIS A 1 50  ? -39.35750 -28.75262 13.55599  1.000 41.26611  ? 50  HIS A CB   1 
ATOM   743  C CG   . HIS A 1 50  ? -39.32608 -28.77242 15.05527  1.000 72.03704  ? 50  HIS A CG   1 
ATOM   744  N ND1  . HIS A 1 50  ? -40.16185 -27.99616 15.83031  1.000 69.42777  ? 50  HIS A ND1  1 
ATOM   745  C CD2  . HIS A 1 50  ? -38.56135 -29.47925 15.92099  1.000 72.96092  ? 50  HIS A CD2  1 
ATOM   746  C CE1  . HIS A 1 50  ? -39.91096 -28.22223 17.10767  1.000 78.87017  ? 50  HIS A CE1  1 
ATOM   747  N NE2  . HIS A 1 50  ? -38.94423 -29.11818 17.19010  1.000 69.65009  ? 50  HIS A NE2  1 
ATOM   748  H H    . HIS A 1 50  ? -37.42689 -30.47003 12.87964  1.000 40.26344  ? 50  HIS A H    1 
ATOM   749  H HA   . HIS A 1 50  ? -40.12087 -30.62588 13.27824  1.000 53.17907  ? 50  HIS A HA   1 
ATOM   750  H HB2  . HIS A 1 50  ? -38.57353 -28.27020 13.25012  1.000 49.67787  ? 50  HIS A HB2  1 
ATOM   751  H HB3  . HIS A 1 50  ? -40.16227 -28.28481 13.28323  1.000 49.67787  ? 50  HIS A HB3  1 
ATOM   752  H HD2  . HIS A 1 50  ? -37.90036 -30.09431 15.69805  1.000 87.71164  ? 50  HIS A HD2  1 
ATOM   753  H HE1  . HIS A 1 50  ? -40.34185 -27.81901 17.82646  1.000 94.80274  ? 50  HIS A HE1  1 
ATOM   754  H HE2  . HIS A 1 50  ? -38.60877 -29.42572 17.91981  1.000 83.73865  ? 50  HIS A HE2  1 
ATOM   755  N N    . LYS A 1 51  ? -40.73276 -30.25272 10.92285  1.000 38.13641  ? 51  LYS A N    1 
ATOM   756  C CA   . LYS A 1 51  ? -41.03083 -30.22371 9.49803   1.000 41.81140  ? 51  LYS A CA   1 
ATOM   757  C C    . LYS A 1 51  ? -42.10344 -29.17715 9.24140   1.000 37.67090  ? 51  LYS A C    1 
ATOM   758  O O    . LYS A 1 51  ? -43.15911 -29.19611 9.88199   1.000 41.21349  ? 51  LYS A O    1 
ATOM   759  C CB   . LYS A 1 51  ? -41.51000 -31.59019 8.99559   1.000 27.27002  ? 51  LYS A CB   1 
ATOM   760  C CG   . LYS A 1 51  ? -40.74693 -32.77619 9.56241   1.000 35.03940  ? 51  LYS A CG   1 
ATOM   761  C CD   . LYS A 1 51  ? -39.32003 -32.82613 9.05678   1.000 51.33943  ? 51  LYS A CD   1 
ATOM   762  C CE   . LYS A 1 51  ? -39.28177 -33.19055 7.58830   1.000 44.92576  ? 51  LYS A CE   1 
ATOM   763  N NZ   . LYS A 1 51  ? -38.33687 -34.30993 7.34963   1.000 65.87079  ? 51  LYS A NZ   1 
ATOM   764  H H    . LYS A 1 51  ? -41.42027 -30.41330 11.41391  1.000 45.92223  ? 51  LYS A H    1 
ATOM   765  H HA   . LYS A 1 51  ? -40.22900 -29.98419 9.00752   1.000 50.33222  ? 51  LYS A HA   1 
ATOM   766  H HB2  . LYS A 1 51  ? -42.44255 -31.69883 9.23940   1.000 32.88256  ? 51  LYS A HB2  1 
ATOM   767  H HB3  . LYS A 1 51  ? -41.41431 -31.61495 8.03064   1.000 32.88256  ? 51  LYS A HB3  1 
ATOM   768  H HG2  . LYS A 1 51  ? -40.72324 -32.70810 10.52972  1.000 42.20582  ? 51  LYS A HG2  1 
ATOM   769  H HG3  . LYS A 1 51  ? -41.19069 -33.59733 9.29840   1.000 42.20582  ? 51  LYS A HG3  1 
ATOM   770  H HD2  . LYS A 1 51  ? -38.90614 -31.95604 9.16873   1.000 61.76586  ? 51  LYS A HD2  1 
ATOM   771  H HD3  . LYS A 1 51  ? -38.82387 -33.49584 9.55299   1.000 61.76586  ? 51  LYS A HD3  1 
ATOM   772  H HE2  . LYS A 1 51  ? -40.16580 -33.46641 7.29968   1.000 54.06945  ? 51  LYS A HE2  1 
ATOM   773  H HE3  . LYS A 1 51  ? -38.98832 -32.42385 7.07163   1.000 54.06945  ? 51  LYS A HE3  1 
ATOM   774  H HZ1  . LYS A 1 51  ? -38.31411 -34.50946 6.48259   1.000 79.20349  ? 51  LYS A HZ1  1 
ATOM   775  H HZ2  . LYS A 1 51  ? -37.51902 -34.07966 7.61459   1.000 79.20349  ? 51  LYS A HZ2  1 
ATOM   776  H HZ3  . LYS A 1 51  ? -38.59609 -35.02942 7.80488   1.000 79.20349  ? 51  LYS A HZ3  1 
ATOM   777  N N    . SER A 1 52  ? -41.82781 -28.26359 8.30963   1.000 45.03414  ? 52  SER A N    1 
ATOM   778  C CA   . SER A 1 52  ? -42.79283 -27.25774 7.85852   1.000 34.43525  ? 52  SER A CA   1 
ATOM   779  C C    . SER A 1 52  ? -42.87868 -27.38126 6.34010   1.000 29.33623  ? 52  SER A C    1 
ATOM   780  O O    . SER A 1 52  ? -42.09778 -26.75568 5.61594   1.000 25.59760  ? 52  SER A O    1 
ATOM   781  C CB   . SER A 1 52  ? -42.38151 -25.85800 8.28300   1.000 44.41563  ? 52  SER A CB   1 
ATOM   782  O OG   . SER A 1 52  ? -42.96403 -24.88966 7.42810   1.000 59.17976  ? 52  SER A OG   1 
ATOM   783  H H    . SER A 1 52  ? -41.06704 -28.20475 7.91293   1.000 54.19951  ? 52  SER A H    1 
ATOM   784  H HA   . SER A 1 52  ? -43.66111 -27.44521 8.24819   1.000 41.48084  ? 52  SER A HA   1 
ATOM   785  H HB2  . SER A 1 52  ? -42.68219 -25.70084 9.19173   1.000 53.45730  ? 52  SER A HB2  1 
ATOM   786  H HB3  . SER A 1 52  ? -41.41557 -25.78307 8.23552   1.000 53.45730  ? 52  SER A HB3  1 
ATOM   787  H HG   . SER A 1 52  ? -42.74638 -24.11777 7.67791   1.000 71.17425  ? 52  SER A HG   1 
ATOM   788  N N    . GLY A 1 53  ? -43.82470 -28.17417 5.86194   1.000 25.86301  ? 53  GLY A N    1 
ATOM   789  C CA   . GLY A 1 53  ? -43.88975 -28.43636 4.43531   1.000 24.90451  ? 53  GLY A CA   1 
ATOM   790  C C    . GLY A 1 53  ? -42.61705 -29.12793 3.98664   1.000 32.70092  ? 53  GLY A C    1 
ATOM   791  O O    . GLY A 1 53  ? -42.27912 -30.22276 4.45337   1.000 35.53414  ? 53  GLY A O    1 
ATOM   792  H H    . GLY A 1 53  ? -44.42922 -28.56525 6.33227   1.000 31.19416  ? 53  GLY A H    1 
ATOM   793  H HA2  . GLY A 1 53  ? -44.64796 -29.00783 4.23670   1.000 30.04396  ? 53  GLY A HA2  1 
ATOM   794  H HA3  . GLY A 1 53  ? -43.98627 -27.60303 3.94835   1.000 30.04396  ? 53  GLY A HA3  1 
ATOM   795  N N    . GLU A 1 54  ? -41.88417 -28.48609 3.08239   1.000 29.11913  ? 54  GLU A N    1 
ATOM   796  C CA   . GLU A 1 54  ? -40.64302 -29.04058 2.55868   1.000 30.00605  ? 54  GLU A CA   1 
ATOM   797  C C    . GLU A 1 54  ? -39.41203 -28.54806 3.30664   1.000 28.90377  ? 54  GLU A C    1 
ATOM   798  O O    . GLU A 1 54  ? -38.29448 -28.92919 2.94570   1.000 38.52202  ? 54  GLU A O    1 
ATOM   799  C CB   . GLU A 1 54  ? -40.51529 -28.71113 1.06973   1.000 34.08659  ? 54  GLU A CB   1 
ATOM   800  C CG   . GLU A 1 54  ? -41.51528 -29.46734 0.21052   1.000 40.82987  ? 54  GLU A CG   1 
ATOM   801  C CD   . GLU A 1 54  ? -41.29906 -30.96883 0.26148   1.000 37.59438  ? 54  GLU A CD   1 
ATOM   802  O OE1  . GLU A 1 54  ? -40.12883 -31.40188 0.21482   1.000 37.54332  ? 54  GLU A OE1  1 
ATOM   803  O OE2  . GLU A 1 54  ? -42.29513 -31.71347 0.36039   1.000 43.84371  ? 54  GLU A OE2  1 
ATOM   804  H H    . GLU A 1 54  ? -42.08842 -27.71827 2.75324   1.000 35.10150  ? 54  GLU A H    1 
ATOM   805  H HA   . GLU A 1 54  ? -40.66914 -30.00615 2.64751   1.000 36.16580  ? 54  GLU A HA   1 
ATOM   806  H HB2  . GLU A 1 54  ? -40.66793 -27.76169 0.94258   1.000 41.06245  ? 54  GLU A HB2  1 
ATOM   807  H HB3  . GLU A 1 54  ? -39.62339 -28.94683 0.76996   1.000 41.06245  ? 54  GLU A HB3  1 
ATOM   808  H HG2  . GLU A 1 54  ? -42.41255 -29.28061 0.52823   1.000 49.15439  ? 54  GLU A HG2  1 
ATOM   809  H HG3  . GLU A 1 54  ? -41.42333 -29.18023 -0.71144  1.000 49.15439  ? 54  GLU A HG3  1 
ATOM   810  N N    . PHE A 1 55  ? -39.58890 -27.73084 4.33892   1.000 25.80725  ? 55  PHE A N    1 
ATOM   811  C CA   . PHE A 1 55  ? -38.48369 -27.24763 5.15686   1.000 40.03597  ? 55  PHE A CA   1 
ATOM   812  C C    . PHE A 1 55  ? -38.28417 -28.21660 6.31655   1.000 28.86491  ? 55  PHE A C    1 
ATOM   813  O O    . PHE A 1 55  ? -39.19019 -28.40463 7.13512   1.000 30.69213  ? 55  PHE A O    1 
ATOM   814  C CB   . PHE A 1 55  ? -38.77971 -25.83496 5.65986   1.000 37.05574  ? 55  PHE A CB   1 
ATOM   815  C CG   . PHE A 1 55  ? -37.58839 -25.12535 6.24535   1.000 39.86495  ? 55  PHE A CG   1 
ATOM   816  C CD1  . PHE A 1 55  ? -36.70856 -24.42618 5.43260   1.000 33.07181  ? 55  PHE A CD1  1 
ATOM   817  C CD2  . PHE A 1 55  ? -37.36295 -25.13838 7.61208   1.000 25.27224  ? 55  PHE A CD2  1 
ATOM   818  C CE1  . PHE A 1 55  ? -35.61849 -23.76441 5.97248   1.000 28.31267  ? 55  PHE A CE1  1 
ATOM   819  C CE2  . PHE A 1 55  ? -36.27610 -24.48106 8.15603   1.000 35.84909  ? 55  PHE A CE2  1 
ATOM   820  C CZ   . PHE A 1 55  ? -35.40408 -23.79060 7.33524   1.000 29.85360  ? 55  PHE A CZ   1 
ATOM   821  H H    . PHE A 1 55  ? -40.35649 -27.43589 4.59074   1.000 31.12724  ? 55  PHE A H    1 
ATOM   822  H HA   . PHE A 1 55  ? -37.66449 -27.21516 4.63844   1.000 48.20170  ? 55  PHE A HA   1 
ATOM   823  H HB2  . PHE A 1 55  ? -39.10293 -25.30248 4.91629   1.000 44.62543  ? 55  PHE A HB2  1 
ATOM   824  H HB3  . PHE A 1 55  ? -39.45908 -25.88767 6.35020   1.000 44.62543  ? 55  PHE A HB3  1 
ATOM   825  H HD1  . PHE A 1 55  ? -36.85236 -24.40149 4.51412   1.000 39.84471  ? 55  PHE A HD1  1 
ATOM   826  H HD2  . PHE A 1 55  ? -37.95018 -25.59504 8.17023   1.000 30.48523  ? 55  PHE A HD2  1 
ATOM   827  H HE1  . PHE A 1 55  ? -35.03193 -23.30310 5.41746   1.000 34.13374  ? 55  PHE A HE1  1 
ATOM   828  H HE2  . PHE A 1 55  ? -36.13124 -24.50316 9.07441   1.000 43.17745  ? 55  PHE A HE2  1 
ATOM   829  H HZ   . PHE A 1 55  ? -34.67442 -23.34467 7.70080   1.000 35.98286  ? 55  PHE A HZ   1 
ATOM   830  N N    . CYS A 1 56  ? -37.11051 -28.83997 6.37315   1.000 31.61654  ? 56  CYS A N    1 
ATOM   831  C CA   . CYS A 1 56  ? -36.76640 -29.80845 7.40663   1.000 31.18948  ? 56  CYS A CA   1 
ATOM   832  C C    . CYS A 1 56  ? -35.66090 -29.22211 8.27369   1.000 38.51047  ? 56  CYS A C    1 
ATOM   833  O O    . CYS A 1 56  ? -34.65327 -28.73521 7.75090   1.000 35.10164  ? 56  CYS A O    1 
ATOM   834  C CB   . CYS A 1 56  ? -36.31845 -31.13257 6.78621   1.000 28.62565  ? 56  CYS A CB   1 
ATOM   835  S SG   . CYS A 1 56  ? -36.23485 -32.50537 7.95429   1.000 39.96319  ? 56  CYS A SG   1 
ATOM   836  H H    . CYS A 1 56  ? -36.47772 -28.71326 5.80472   1.000 38.09838  ? 56  CYS A H    1 
ATOM   837  H HA   . CYS A 1 56  ? -37.53744 -29.98839 7.96700   1.000 37.58592  ? 56  CYS A HA   1 
ATOM   838  H HB2  . CYS A 1 56  ? -36.94734 -31.37688 6.08928   1.000 34.50932  ? 56  CYS A HB2  1 
ATOM   839  H HB3  . CYS A 1 56  ? -35.43331 -31.01383 6.40761   1.000 34.50932  ? 56  CYS A HB3  1 
ATOM   840  H HG   . CYS A 1 56  ? -35.60024 -32.16384 8.91378   1.000 48.11437  ? 56  CYS A HG   1 
ATOM   841  N N    . ARG A 1 57  ? -35.84998 -29.27743 9.59254   1.000 36.82347  ? 57  ARG A N    1 
ATOM   842  C CA   . ARG A 1 57  ? -35.02332 -28.55266 10.55356  1.000 30.93668  ? 57  ARG A CA   1 
ATOM   843  C C    . ARG A 1 57  ? -34.55665 -29.52248 11.62702  1.000 32.56735  ? 57  ARG A C    1 
ATOM   844  O O    . ARG A 1 57  ? -35.38099 -30.09625 12.34581  1.000 35.26054  ? 57  ARG A O    1 
ATOM   845  C CB   . ARG A 1 57  ? -35.82234 -27.39936 11.17130  1.000 30.42006  ? 57  ARG A CB   1 
ATOM   846  C CG   . ARG A 1 57  ? -35.01407 -26.37155 11.94134  1.000 38.03966  ? 57  ARG A CG   1 
ATOM   847  C CD   . ARG A 1 57  ? -35.94206 -25.37809 12.64544  1.000 34.19965  ? 57  ARG A CD   1 
ATOM   848  N NE   . ARG A 1 57  ? -35.77719 -25.40641 14.09511  1.000 53.04614  ? 57  ARG A NE   1 
ATOM   849  C CZ   . ARG A 1 57  ? -35.14045 -24.48109 14.80329  1.000 79.53758  ? 57  ARG A CZ   1 
ATOM   850  N NH1  . ARG A 1 57  ? -34.62541 -23.40292 14.23365  1.000 66.30181  ? 57  ARG A NH1  1 
ATOM   851  N NH2  . ARG A 1 57  ? -35.02068 -24.64062 16.11844  1.000 45.66446  ? 57  ARG A NH2  1 
ATOM   852  H H    . ARG A 1 57  ? -36.47027 -29.74279 9.96439   1.000 44.34670  ? 57  ARG A H    1 
ATOM   853  H HA   . ARG A 1 57  ? -34.23631 -28.19276 10.11540  1.000 37.28256  ? 57  ARG A HA   1 
ATOM   854  H HB2  . ARG A 1 57  ? -36.27834 -26.92874 10.45612  1.000 36.66261  ? 57  ARG A HB2  1 
ATOM   855  H HB3  . ARG A 1 57  ? -36.47058 -27.77499 11.78741  1.000 36.66261  ? 57  ARG A HB3  1 
ATOM   856  H HG2  . ARG A 1 57  ? -34.47397 -26.81851 12.61173  1.000 45.80613  ? 57  ARG A HG2  1 
ATOM   857  H HG3  . ARG A 1 57  ? -34.44379 -25.88110 11.32886  1.000 45.80613  ? 57  ARG A HG3  1 
ATOM   858  H HD2  . ARG A 1 57  ? -35.74263 -24.48079 12.33564  1.000 41.19812  ? 57  ARG A HD2  1 
ATOM   859  H HD3  . ARG A 1 57  ? -36.86338 -25.60248 12.44118  1.000 41.19812  ? 57  ARG A HD3  1 
ATOM   860  H HE   . ARG A 1 57  ? -36.11730 -26.07101 14.52200  1.000 63.81391  ? 57  ARG A HE   1 
ATOM   861  H HH11 . ARG A 1 57  ? -34.69903 -23.28847 13.38449  1.000 79.72072  ? 57  ARG A HH11 1 
ATOM   862  H HH12 . ARG A 1 57  ? -34.21717 -22.81689 14.71273  1.000 79.72072  ? 57  ARG A HH12 1 
ATOM   863  H HH21 . ARG A 1 57  ? -35.35348 -25.33617 16.49929  1.000 54.95589  ? 57  ARG A HH21 1 
ATOM   864  H HH22 . ARG A 1 57  ? -34.61046 -24.04819 16.58786  1.000 54.95589  ? 57  ARG A HH22 1 
ATOM   865  N N    . LEU A 1 58  ? -33.24142 -29.70870 11.73600  1.000 28.29650  ? 58  LEU A N    1 
ATOM   866  C CA   . LEU A 1 58  ? -32.66285 -30.67706 12.66272  1.000 25.33101  ? 58  LEU A CA   1 
ATOM   867  C C    . LEU A 1 58  ? -31.84556 -29.94166 13.71479  1.000 33.89669  ? 58  LEU A C    1 
ATOM   868  O O    . LEU A 1 58  ? -30.78643 -29.38206 13.40755  1.000 31.26789  ? 58  LEU A O    1 
ATOM   869  C CB   . LEU A 1 58  ? -31.79396 -31.70037 11.92742  1.000 26.91419  ? 58  LEU A CB   1 
ATOM   870  C CG   . LEU A 1 58  ? -32.54589 -32.80930 11.19096  1.000 39.60238  ? 58  LEU A CG   1 
ATOM   871  C CD1  . LEU A 1 58  ? -33.18842 -32.27374 9.92553   1.000 35.18675  ? 58  LEU A CD1  1 
ATOM   872  C CD2  . LEU A 1 58  ? -31.62986 -33.98060 10.86945  1.000 46.15427  ? 58  LEU A CD2  1 
ATOM   873  H H    . LEU A 1 58  ? -32.65644 -29.27816 11.27553  1.000 34.11434  ? 58  LEU A H    1 
ATOM   874  H HA   . LEU A 1 58  ? -33.38696 -31.14205 13.11032  1.000 30.55575  ? 58  LEU A HA   1 
ATOM   875  H HB2  . LEU A 1 58  ? -31.26139 -31.22766 11.26877  1.000 32.45556  ? 58  LEU A HB2  1 
ATOM   876  H HB3  . LEU A 1 58  ? -31.21474 -32.12827 12.57726  1.000 32.45556  ? 58  LEU A HB3  1 
ATOM   877  H HG   . LEU A 1 58  ? -33.24893 -33.13809 11.77281  1.000 47.68139  ? 58  LEU A HG   1 
ATOM   878  H HD11 . LEU A 1 58  ? -33.65124 -32.99776 9.47555   1.000 42.38264  ? 58  LEU A HD11 1 
ATOM   879  H HD12 . LEU A 1 58  ? -33.81832 -31.57518 10.16246  1.000 42.38264  ? 58  LEU A HD12 1 
ATOM   880  H HD13 . LEU A 1 58  ? -32.49699 -31.91379 9.34824   1.000 42.38264  ? 58  LEU A HD13 1 
ATOM   881  H HD21 . LEU A 1 58  ? -32.14210 -34.66596 10.41253  1.000 55.54367  ? 58  LEU A HD21 1 
ATOM   882  H HD22 . LEU A 1 58  ? -30.90928 -33.67061 10.29885  1.000 55.54367  ? 58  LEU A HD22 1 
ATOM   883  H HD23 . LEU A 1 58  ? -31.26772 -34.33465 11.69674  1.000 55.54367  ? 58  LEU A HD23 1 
ATOM   884  N N    . ARG A 1 59  ? -32.33356 -29.95461 14.95069  1.000 34.65102  ? 59  ARG A N    1 
ATOM   885  C CA   . ARG A 1 59  ? -31.60858 -29.42016 16.09422  1.000 36.64633  ? 59  ARG A CA   1 
ATOM   886  C C    . ARG A 1 59  ? -30.89721 -30.56730 16.80121  1.000 42.72493  ? 59  ARG A C    1 
ATOM   887  O O    . ARG A 1 59  ? -31.54798 -31.48839 17.30631  1.000 34.50224  ? 59  ARG A O    1 
ATOM   888  C CB   . ARG A 1 59  ? -32.55158 -28.70644 17.06202  1.000 36.89609  ? 59  ARG A CB   1 
ATOM   889  C CG   . ARG A 1 59  ? -31.88659 -28.27532 18.36677  1.000 56.33697  ? 59  ARG A CG   1 
ATOM   890  C CD   . ARG A 1 59  ? -30.84217 -27.19103 18.13347  1.000 53.00732  ? 59  ARG A CD   1 
ATOM   891  N NE   . ARG A 1 59  ? -31.46051 -25.91476 17.79327  1.000 65.24345  ? 59  ARG A NE   1 
ATOM   892  C CZ   . ARG A 1 59  ? -30.79461 -24.81878 17.45450  1.000 54.93581  ? 59  ARG A CZ   1 
ATOM   893  N NH1  . ARG A 1 59  ? -29.47323 -24.80318 17.39101  1.000 70.28529  ? 59  ARG A NH1  1 
ATOM   894  N NH2  . ARG A 1 59  ? -31.47255 -23.71040 17.16994  1.000 69.66902  ? 59  ARG A NH2  1 
ATOM   895  H H    . ARG A 1 59  ? -33.10399 -30.27693 15.15597  1.000 41.73976  ? 59  ARG A H    1 
ATOM   896  H HA   . ARG A 1 59  ? -30.94858 -28.77995 15.78530  1.000 44.13413  ? 59  ARG A HA   1 
ATOM   897  H HB2  . ARG A 1 59  ? -32.89772 -27.91028 16.62935  1.000 44.43384  ? 59  ARG A HB2  1 
ATOM   898  H HB3  . ARG A 1 59  ? -33.28055 -29.30603 17.28565  1.000 44.43384  ? 59  ARG A HB3  1 
ATOM   899  H HG2  . ARG A 1 59  ? -32.56053 -27.92398 18.96948  1.000 67.76290  ? 59  ARG A HG2  1 
ATOM   900  H HG3  . ARG A 1 59  ? -31.44661 -29.03977 18.77043  1.000 67.76290  ? 59  ARG A HG3  1 
ATOM   901  H HD2  . ARG A 1 59  ? -30.31903 -27.07042 18.94136  1.000 63.76733  ? 59  ARG A HD2  1 
ATOM   902  H HD3  . ARG A 1 59  ? -30.26433 -27.45469 17.40033  1.000 63.76733  ? 59  ARG A HD3  1 
ATOM   903  H HE   . ARG A 1 59  ? -32.31907 -25.86948 17.81379  1.000 78.45068  ? 59  ARG A HE   1 
ATOM   904  H HH11 . ARG A 1 59  ? -29.02561 -25.51494 17.57166  1.000 84.50089  ? 59  ARG A HH11 1 
ATOM   905  H HH12 . ARG A 1 59  ? -29.06189 -24.08127 17.16908  1.000 84.50089  ? 59  ARG A HH12 1 
ATOM   906  H HH21 . ARG A 1 59  ? -32.33176 -23.71045 17.20685  1.000 83.76137  ? 59  ARG A HH21 1 
ATOM   907  H HH22 . ARG A 1 59  ? -31.05168 -22.99369 16.94903  1.000 83.76137  ? 59  ARG A HH22 1 
ATOM   908  N N    . PHE A 1 60  ? -29.58133 -30.50153 16.85152  1.000 41.42270  ? 60  PHE A N    1 
ATOM   909  C CA   . PHE A 1 60  ? -28.80420 -31.53280 17.51735  1.000 32.31756  ? 60  PHE A CA   1 
ATOM   910  C C    . PHE A 1 60  ? -28.61401 -31.19435 18.98721  1.000 44.52625  ? 60  PHE A C    1 
ATOM   911  O O    . PHE A 1 60  ? -28.67825 -30.02747 19.38647  1.000 41.47544  ? 60  PHE A O    1 
ATOM   912  C CB   . PHE A 1 60  ? -27.45676 -31.69731 16.82228  1.000 29.34565  ? 60  PHE A CB   1 
ATOM   913  C CG   . PHE A 1 60  ? -27.56328 -32.34241 15.47523  1.000 27.42472  ? 60  PHE A CG   1 
ATOM   914  C CD1  . PHE A 1 60  ? -27.86110 -31.58637 14.35398  1.000 31.79137  ? 60  PHE A CD1  1 
ATOM   915  C CD2  . PHE A 1 60  ? -27.39352 -33.70823 15.33261  1.000 34.41335  ? 60  PHE A CD2  1 
ATOM   916  C CE1  . PHE A 1 60  ? -27.97563 -32.17792 13.11448  1.000 30.08823  ? 60  PHE A CE1  1 
ATOM   917  C CE2  . PHE A 1 60  ? -27.50645 -34.30658 14.09380  1.000 41.54395  ? 60  PHE A CE2  1 
ATOM   918  C CZ   . PHE A 1 60  ? -27.80034 -33.54063 12.98401  1.000 38.99821  ? 60  PHE A CZ   1 
ATOM   919  H H    . PHE A 1 60  ? -29.11141 -29.86883 16.50734  1.000 49.86578  ? 60  PHE A H    1 
ATOM   920  H HA   . PHE A 1 60  ? -29.26929 -32.38258 17.46779  1.000 38.93961  ? 60  PHE A HA   1 
ATOM   921  H HB2  . PHE A 1 60  ? -27.05580 -30.82212 16.70325  1.000 34.42208  ? 60  PHE A HB2  1 
ATOM   922  H HB3  . PHE A 1 60  ? -26.88411 -32.25225 17.37456  1.000 34.42208  ? 60  PHE A HB3  1 
ATOM   923  H HD1  . PHE A 1 60  ? -27.98531 -30.66858 14.43835  1.000 38.30819  ? 60  PHE A HD1  1 
ATOM   924  H HD2  . PHE A 1 60  ? -27.20134 -34.22848 16.07913  1.000 41.45456  ? 60  PHE A HD2  1 
ATOM   925  H HE1  . PHE A 1 60  ? -28.17069 -31.65972 12.36728  1.000 36.26441  ? 60  PHE A HE1  1 
ATOM   926  H HE2  . PHE A 1 60  ? -27.38468 -35.22449 14.00716  1.000 50.01128  ? 60  PHE A HE2  1 
ATOM   927  H HZ   . PHE A 1 60  ? -27.88018 -33.94236 12.14906  1.000 46.95639  ? 60  PHE A HZ   1 
ATOM   928  N N    . PRO A 1 61  ? -28.39546 -32.20993 19.82669  1.000 34.71002  ? 61  PRO A N    1 
ATOM   929  C CA   . PRO A 1 61  ? -28.29892 -31.94269 21.27156  1.000 37.59312  ? 61  PRO A CA   1 
ATOM   930  C C    . PRO A 1 61  ? -27.01744 -31.23323 21.66399  1.000 58.68983  ? 61  PRO A C    1 
ATOM   931  O O    . PRO A 1 61  ? -27.03929 -30.36167 22.54258  1.000 47.36519  ? 61  PRO A O    1 
ATOM   932  C CB   . PRO A 1 61  ? -28.38724 -33.34771 21.88378  1.000 39.37141  ? 61  PRO A CB   1 
ATOM   933  C CG   . PRO A 1 61  ? -27.81636 -34.24277 20.81852  1.000 42.24199  ? 61  PRO A CG   1 
ATOM   934  C CD   . PRO A 1 61  ? -28.25846 -33.64461 19.51104  1.000 38.10406  ? 61  PRO A CD   1 
ATOM   935  H HA   . PRO A 1 61  ? -29.05667 -31.41228 21.56374  1.000 44.31904  ? 61  PRO A HA   1 
ATOM   936  H HB2  . PRO A 1 61  ? -27.86171 -33.39153 22.69790  1.000 46.45299  ? 61  PRO A HB2  1 
ATOM   937  H HB3  . PRO A 1 61  ? -29.31161 -33.57265 22.07308  1.000 46.45299  ? 61  PRO A HB3  1 
ATOM   938  H HG2  . PRO A 1 61  ? -26.84856 -34.25404 20.88280  1.000 50.84892  ? 61  PRO A HG2  1 
ATOM   939  H HG3  . PRO A 1 61  ? -28.16623 -35.14150 20.92233  1.000 50.84892  ? 61  PRO A HG3  1 
ATOM   940  H HD2  . PRO A 1 61  ? -27.58929 -33.78479 18.82295  1.000 45.88342  ? 61  PRO A HD2  1 
ATOM   941  H HD3  . PRO A 1 61  ? -29.10768 -34.01914 19.22915  1.000 45.88342  ? 61  PRO A HD3  1 
ATOM   942  N N    . LYS A 1 62  ? -25.89900 -31.59640 21.05332  1.000 51.86505  ? 62  LYS A N    1 
ATOM   943  C CA   . LYS A 1 62  ? -24.61685 -30.94704 21.25969  1.000 56.47033  ? 62  LYS A CA   1 
ATOM   944  C C    . LYS A 1 62  ? -24.18754 -30.25262 19.97256  1.000 41.92551  ? 62  LYS A C    1 
ATOM   945  O O    . LYS A 1 62  ? -24.71030 -30.55210 18.89159  1.000 46.61864  ? 62  LYS A O    1 
ATOM   946  C CB   . LYS A 1 62  ? -23.54701 -31.96410 21.68172  1.000 49.88486  ? 62  LYS A CB   1 
ATOM   947  C CG   . LYS A 1 62  ? -24.01825 -33.01321 22.69132  1.000 62.92641  ? 62  LYS A CG   1 
ATOM   948  C CD   . LYS A 1 62  ? -23.95136 -34.41928 22.08943  1.000 77.44784  ? 62  LYS A CD   1 
ATOM   949  C CE   . LYS A 1 62  ? -24.76303 -35.43257 22.89020  1.000 71.36037  ? 62  LYS A CE   1 
ATOM   950  N NZ   . LYS A 1 62  ? -25.15437 -36.61241 22.05890  1.000 62.79423  ? 62  LYS A NZ   1 
ATOM   951  H H    . LYS A 1 62  ? -25.85778 -32.24522 20.49035  1.000 62.39661  ? 62  LYS A H    1 
ATOM   952  H HA   . LYS A 1 62  ? -24.68490 -30.29029 21.97029  1.000 67.92294  ? 62  LYS A HA   1 
ATOM   953  H HB2  . LYS A 1 62  ? -23.24320 -32.43664 20.89095  1.000 60.02037  ? 62  LYS A HB2  1 
ATOM   954  H HB3  . LYS A 1 62  ? -22.80768 -31.48297 22.08522  1.000 60.02037  ? 62  LYS A HB3  1 
ATOM   955  H HG2  . LYS A 1 62  ? -23.44768 -32.98702 23.47533  1.000 75.67023  ? 62  LYS A HG2  1 
ATOM   956  H HG3  . LYS A 1 62  ? -24.93688 -32.83012 22.94329  1.000 75.67023  ? 62  LYS A HG3  1 
ATOM   957  H HD2  . LYS A 1 62  ? -24.30522 -34.39589 21.18658  1.000 93.09595  ? 62  LYS A HD2  1 
ATOM   958  H HD3  . LYS A 1 62  ? -23.02794 -34.71596 22.07625  1.000 93.09595  ? 62  LYS A HD3  1 
ATOM   959  H HE2  . LYS A 1 62  ? -24.23138 -35.75003 23.63684  1.000 85.79099  ? 62  LYS A HE2  1 
ATOM   960  H HE3  . LYS A 1 62  ? -25.57241 -35.00856 23.21579  1.000 85.79099  ? 62  LYS A HE3  1 
ATOM   961  H HZ1  . LYS A 1 62  ? -24.42686 -37.02952 21.76083  1.000 75.51162  ? 62  LYS A HZ1  1 
ATOM   962  H HZ2  . LYS A 1 62  ? -25.64047 -36.34631 21.36248  1.000 75.51162  ? 62  LYS A HZ2  1 
ATOM   963  H HZ3  . LYS A 1 62  ? -25.63476 -37.18190 22.54573  1.000 75.51162  ? 62  LYS A HZ3  1 
ATOM   964  N N    . PRO A 1 63  ? -23.25905 -29.30206 20.04181  1.000 42.20805  ? 63  PRO A N    1 
ATOM   965  C CA   . PRO A 1 63  ? -22.73478 -28.70784 18.80654  1.000 46.36509  ? 63  PRO A CA   1 
ATOM   966  C C    . PRO A 1 63  ? -21.93077 -29.73073 18.01614  1.000 33.81982  ? 63  PRO A C    1 
ATOM   967  O O    . PRO A 1 63  ? -21.12507 -30.47536 18.57708  1.000 43.06356  ? 63  PRO A O    1 
ATOM   968  C CB   . PRO A 1 63  ? -21.85748 -27.55036 19.30154  1.000 42.65898  ? 63  PRO A CB   1 
ATOM   969  C CG   . PRO A 1 63  ? -21.53792 -27.88477 20.72419  1.000 50.83582  ? 63  PRO A CG   1 
ATOM   970  C CD   . PRO A 1 63  ? -22.72277 -28.64339 21.24986  1.000 39.45439  ? 63  PRO A CD   1 
ATOM   971  H HA   . PRO A 1 63  ? -23.44956 -28.35086 18.25649  1.000 55.79665  ? 63  PRO A HA   1 
ATOM   972  H HB2  . PRO A 1 63  ? -21.04929 -27.49746 18.76775  1.000 51.34932  ? 63  PRO A HB2  1 
ATOM   973  H HB3  . PRO A 1 63  ? -22.34871 -26.71597 19.24333  1.000 51.34932  ? 63  PRO A HB3  1 
ATOM   974  H HG2  . PRO A 1 63  ? -20.73782 -28.43207 20.75879  1.000 61.16152  ? 63  PRO A HG2  1 
ATOM   975  H HG3  . PRO A 1 63  ? -21.40292 -27.06751 21.22894  1.000 61.16152  ? 63  PRO A HG3  1 
ATOM   976  H HD2  . PRO A 1 63  ? -22.44877 -29.29980 21.90937  1.000 46.55256  ? 63  PRO A HD2  1 
ATOM   977  H HD3  . PRO A 1 63  ? -23.37740 -28.03981 21.63463  1.000 46.55256  ? 63  PRO A HD3  1 
ATOM   978  N N    . ILE A 1 64  ? -22.17452 -29.77666 16.71100  1.000 39.82565  ? 64  ILE A N    1 
ATOM   979  C CA   . ILE A 1 64  ? -21.51930 -30.73727 15.82108  1.000 48.36041  ? 64  ILE A CA   1 
ATOM   980  C C    . ILE A 1 64  ? -20.42926 -30.07454 14.98947  1.000 36.46361  ? 64  ILE A C    1 
ATOM   981  O O    . ILE A 1 64  ? -19.31293 -30.58469 14.90115  1.000 34.40374  ? 64  ILE A O    1 
ATOM   982  C CB   . ILE A 1 64  ? -22.56524 -31.43295 14.92137  1.000 38.24750  ? 64  ILE A CB   1 
ATOM   983  C CG1  . ILE A 1 64  ? -23.05773 -32.73355 15.56471  1.000 45.41454  ? 64  ILE A CG1  1 
ATOM   984  C CG2  . ILE A 1 64  ? -21.98544 -31.74889 13.54872  1.000 46.39431  ? 64  ILE A CG2  1 
ATOM   985  C CD1  . ILE A 1 64  ? -23.89499 -32.53837 16.80843  1.000 45.38889  ? 64  ILE A CD1  1 
ATOM   986  H H    . ILE A 1 64  ? -22.72494 -29.25343 16.30744  1.000 47.94932  ? 64  ILE A H    1 
ATOM   987  H HA   . ILE A 1 64  ? -21.09691 -31.41881 16.36695  1.000 58.19104  ? 64  ILE A HA   1 
ATOM   988  H HB   . ILE A 1 64  ? -23.30905 -30.81836 14.82172  1.000 46.05554  ? 64  ILE A HB   1 
ATOM   989  H HG12 . ILE A 1 64  ? -23.60003 -33.21220 14.91841  1.000 54.65599  ? 64  ILE A HG12 1 
ATOM   990  H HG13 . ILE A 1 64  ? -22.28663 -33.26786 15.81132  1.000 54.65599  ? 64  ILE A HG13 1 
ATOM   991  H HG21 . ILE A 1 64  ? -22.57555 -32.36834 13.09161  1.000 55.83171  ? 64  ILE A HG21 1 
ATOM   992  H HG22 . ILE A 1 64  ? -21.91140 -30.92619 13.04020  1.000 55.83171  ? 64  ILE A HG22 1 
ATOM   993  H HG23 . ILE A 1 64  ? -21.10875 -32.14864 13.66060  1.000 55.83171  ? 64  ILE A HG23 1 
ATOM   994  H HD11 . ILE A 1 64  ? -23.34016 -32.15514 17.50571  1.000 54.62521  ? 64  ILE A HD11 1 
ATOM   995  H HD12 . ILE A 1 64  ? -24.62979 -31.93917 16.60365  1.000 54.62521  ? 64  ILE A HD12 1 
ATOM   996  H HD13 . ILE A 1 64  ? -24.23968 -33.39849 17.09528  1.000 54.62521  ? 64  ILE A HD13 1 
ATOM   997  N N    . ARG A 1 65  ? -20.73744 -28.94056 14.35995  1.000 39.93706  ? 65  ARG A N    1 
ATOM   998  C CA   . ARG A 1 65  ? -19.76735 -28.21715 13.53961  1.000 35.03304  ? 65  ARG A CA   1 
ATOM   999  C C    . ARG A 1 65  ? -19.23359 -27.04853 14.36481  1.000 38.40258  ? 65  ARG A C    1 
ATOM   1000 O O    . ARG A 1 65  ? -19.65404 -25.89995 14.22314  1.000 47.71311  ? 65  ARG A O    1 
ATOM   1001 C CB   . ARG A 1 65  ? -20.40118 -27.75269 12.23246  1.000 34.06748  ? 65  ARG A CB   1 
ATOM   1002 C CG   . ARG A 1 65  ? -20.56428 -28.84963 11.19036  1.000 36.97936  ? 65  ARG A CG   1 
ATOM   1003 C CD   . ARG A 1 65  ? -19.21771 -29.37157 10.70609  1.000 45.24121  ? 65  ARG A CD   1 
ATOM   1004 N NE   . ARG A 1 65  ? -18.38907 -28.30053 10.16752  1.000 40.05297  ? 65  ARG A NE   1 
ATOM   1005 C CZ   . ARG A 1 65  ? -18.44746 -27.86425 8.91701   1.000 43.09429  ? 65  ARG A CZ   1 
ATOM   1006 N NH1  . ARG A 1 65  ? -19.26578 -28.40981 8.03159   1.000 31.25068  ? 65  ARG A NH1  1 
ATOM   1007 N NH2  . ARG A 1 65  ? -17.66964 -26.85081 8.54727   1.000 28.97219  ? 65  ARG A NH2  1 
ATOM   1008 H H    . ARG A 1 65  ? -21.51103 -28.56634 14.39335  1.000 48.08302  ? 65  ARG A H    1 
ATOM   1009 H HA   . ARG A 1 65  ? -19.02878 -28.80699 13.32162  1.000 42.19819  ? 65  ARG A HA   1 
ATOM   1010 H HB2  . ARG A 1 65  ? -21.28286 -27.39714 12.42511  1.000 41.03952  ? 65  ARG A HB2  1 
ATOM   1011 H HB3  . ARG A 1 65  ? -19.84176 -27.06102 11.84576  1.000 41.03952  ? 65  ARG A HB3  1 
ATOM   1012 H HG2  . ARG A 1 65  ? -21.05548 -29.59034 11.57891  1.000 44.53377  ? 65  ARG A HG2  1 
ATOM   1013 H HG3  . ARG A 1 65  ? -21.04609 -28.49655 10.42610  1.000 44.53377  ? 65  ARG A HG3  1 
ATOM   1014 H HD2  . ARG A 1 65  ? -18.74515 -29.77787 11.44940  1.000 54.44799  ? 65  ARG A HD2  1 
ATOM   1015 H HD3  . ARG A 1 65  ? -19.36099 -30.02731 10.00582  1.000 54.44799  ? 65  ARG A HD3  1 
ATOM   1016 H HE   . ARG A 1 65  ? -17.82394 -27.92616 10.69674  1.000 48.22211  ? 65  ARG A HE   1 
ATOM   1017 H HH11 . ARG A 1 65  ? -19.77557 -29.06282 8.26243   1.000 37.65936  ? 65  ARG A HH11 1 
ATOM   1018 H HH12 . ARG A 1 65  ? -19.28779 -28.11133 7.22535   1.000 37.65936  ? 65  ARG A HH12 1 
ATOM   1019 H HH21 . ARG A 1 65  ? -17.13755 -26.48715 9.11668   1.000 34.92517  ? 65  ARG A HH21 1 
ATOM   1020 H HH22 . ARG A 1 65  ? -17.69876 -26.55914 7.73876   1.000 34.92517  ? 65  ARG A HH22 1 
ATOM   1021 N N    . THR A 1 66  ? -18.28441 -27.35974 15.24733  1.000 40.59632  ? 66  THR A N    1 
ATOM   1022 C CA   . THR A 1 66  ? -17.70722 -26.34879 16.12143  1.000 41.81565  ? 66  THR A CA   1 
ATOM   1023 C C    . THR A 1 66  ? -16.90562 -25.30071 15.36238  1.000 43.68424  ? 66  THR A C    1 
ATOM   1024 O O    . THR A 1 66  ? -16.58160 -24.25595 15.93826  1.000 48.53016  ? 66  THR A O    1 
ATOM   1025 C CB   . THR A 1 66  ? -16.81248 -27.01660 17.16697  1.000 38.72079  ? 66  THR A CB   1 
ATOM   1026 O OG1  . THR A 1 66  ? -15.85215 -27.85327 16.50952  1.000 48.19227  ? 66  THR A OG1  1 
ATOM   1027 C CG2  . THR A 1 66  ? -17.64321 -27.86131 18.12056  1.000 45.72516  ? 66  THR A CG2  1 
ATOM   1028 H H    . THR A 1 66  ? -17.96001 -28.14862 15.35704  1.000 48.87412  ? 66  THR A H    1 
ATOM   1029 H HA   . THR A 1 66  ? -18.42752 -25.89343 16.58480  1.000 50.33732  ? 66  THR A HA   1 
ATOM   1030 H HB   . THR A 1 66  ? -16.35295 -26.33537 17.68238  1.000 46.62349  ? 66  THR A HB   1 
ATOM   1031 H HG1  . THR A 1 66  ? -16.24042 -28.49807 16.13658  1.000 57.98927  ? 66  THR A HG1  1 
ATOM   1032 H HG21 . THR A 1 66  ? -17.06872 -28.27508 18.78363  1.000 55.02873  ? 66  THR A HG21 1 
ATOM   1033 H HG22 . THR A 1 66  ? -18.29654 -27.30521 18.57312  1.000 55.02873  ? 66  THR A HG22 1 
ATOM   1034 H HG23 . THR A 1 66  ? -18.10802 -28.55645 17.62899  1.000 55.02873  ? 66  THR A HG23 1 
ATOM   1035 N N    . ASP A 1 67  ? -16.58248 -25.54838 14.09387  1.000 47.24782  ? 67  ASP A N    1 
ATOM   1036 C CA   . ASP A 1 67  ? -15.78775 -24.60196 13.32614  1.000 48.83241  ? 67  ASP A CA   1 
ATOM   1037 C C    . ASP A 1 67  ? -16.60671 -23.45057 12.75827  1.000 35.83293  ? 67  ASP A C    1 
ATOM   1038 O O    . ASP A 1 67  ? -16.02400 -22.44161 12.34793  1.000 39.34182  ? 67  ASP A O    1 
ATOM   1039 C CB   . ASP A 1 67  ? -15.08160 -25.32137 12.17382  1.000 35.26452  ? 67  ASP A CB   1 
ATOM   1040 C CG   . ASP A 1 67  ? -16.02807 -26.17555 11.35601  1.000 52.89423  ? 67  ASP A CG   1 
ATOM   1041 O OD1  . ASP A 1 67  ? -16.96765 -26.75374 11.94645  1.000 51.07652  ? 67  ASP A OD1  1 
ATOM   1042 O OD2  . ASP A 1 67  ? -15.83261 -26.27456 10.12685  1.000 53.73449  ? 67  ASP A OD2  1 
ATOM   1043 H H    . ASP A 1 67  ? -16.81149 -26.25453 13.65971  1.000 56.85593  ? 67  ASP A H    1 
ATOM   1044 H HA   . ASP A 1 67  ? -15.11583 -24.22745 13.91704  1.000 58.75743  ? 67  ASP A HA   1 
ATOM   1045 H HB2  . ASP A 1 67  ? -14.68547 -24.66148 11.58345  1.000 42.47596  ? 67  ASP A HB2  1 
ATOM   1046 H HB3  . ASP A 1 67  ? -14.39172 -25.89906 12.53610  1.000 42.47596  ? 67  ASP A HB3  1 
ATOM   1047 N N    . VAL A 1 68  ? -17.92702 -23.56713 12.72365  1.000 42.40437  ? 68  VAL A N    1 
ATOM   1048 C CA   . VAL A 1 68  ? -18.75905 -22.59498 12.04023  1.000 34.52733  ? 68  VAL A CA   1 
ATOM   1049 C C    . VAL A 1 68  ? -19.34654 -21.62101 13.05086  1.000 45.27782  ? 68  VAL A C    1 
ATOM   1050 O O    . VAL A 1 68  ? -19.35451 -21.85714 14.26169  1.000 53.86883  ? 68  VAL A O    1 
ATOM   1051 C CB   . VAL A 1 68  ? -19.88069 -23.28351 11.22750  1.000 32.22504  ? 68  VAL A CB   1 
ATOM   1052 C CG1  . VAL A 1 68  ? -19.30996 -24.42612 10.39511  1.000 40.91590  ? 68  VAL A CG1  1 
ATOM   1053 C CG2  . VAL A 1 68  ? -20.97943 -23.77127 12.15886  1.000 46.12830  ? 68  VAL A CG2  1 
ATOM   1054 H H    . VAL A 1 68  ? -18.36631 -24.20767 13.09288  1.000 51.04378  ? 68  VAL A H    1 
ATOM   1055 H HA   . VAL A 1 68  ? -18.20107 -22.08341 11.43373  1.000 41.59134  ? 68  VAL A HA   1 
ATOM   1056 H HB   . VAL A 1 68  ? -20.27396 -22.64297 10.61436  1.000 38.82859  ? 68  VAL A HB   1 
ATOM   1057 H HG11 . VAL A 1 68  ? -20.00867 -24.77929 9.82243   1.000 49.25762  ? 68  VAL A HG11 1 
ATOM   1058 H HG12 . VAL A 1 68  ? -18.57854 -24.08851 9.85479   1.000 49.25762  ? 68  VAL A HG12 1 
ATOM   1059 H HG13 . VAL A 1 68  ? -18.98798 -25.12063 10.99083  1.000 49.25762  ? 68  VAL A HG13 1 
ATOM   1060 H HG21 . VAL A 1 68  ? -21.46803 -24.48708 11.72322  1.000 55.51250  ? 68  VAL A HG21 1 
ATOM   1061 H HG22 . VAL A 1 68  ? -20.57672 -24.09703 12.97898  1.000 55.51250  ? 68  VAL A HG22 1 
ATOM   1062 H HG23 . VAL A 1 68  ? -21.57807 -23.03356 12.35462  1.000 55.51250  ? 68  VAL A HG23 1 
ATOM   1063 N N    . THR A 1 69  ? -19.83986 -20.50142 12.53715  1.000 41.65305  ? 69  THR A N    1 
ATOM   1064 C CA   . THR A 1 69  ? -20.58492 -19.52060 13.30848  1.000 38.13294  ? 69  THR A CA   1 
ATOM   1065 C C    . THR A 1 69  ? -22.07156 -19.64431 12.99184  1.000 31.74960  ? 69  THR A C    1 
ATOM   1066 O O    . THR A 1 69  ? -22.46285 -20.17059 11.94708  1.000 40.21156  ? 69  THR A O    1 
ATOM   1067 C CB   . THR A 1 69  ? -20.10474 -18.10475 12.98951  1.000 45.01631  ? 69  THR A CB   1 
ATOM   1068 O OG1  . THR A 1 69  ? -20.46081 -17.77332 11.64187  1.000 83.07211  ? 69  THR A OG1  1 
ATOM   1069 C CG2  . THR A 1 69  ? -18.60233 -18.01186 13.13748  1.000 37.52677  ? 69  THR A CG2  1 
ATOM   1070 H H    . THR A 1 69  ? -19.75150 -20.28043 11.71074  1.000 50.14220  ? 69  THR A H    1 
ATOM   1071 H HA   . THR A 1 69  ? -20.44951 -19.67668 14.25621  1.000 45.91807  ? 69  THR A HA   1 
ATOM   1072 H HB   . THR A 1 69  ? -20.51722 -17.47625 13.60249  1.000 54.17811  ? 69  THR A HB   1 
ATOM   1073 H HG1  . THR A 1 69  ? -20.10964 -18.31977 11.10925  1.000 99.84508  ? 69  THR A HG1  1 
ATOM   1074 H HG21 . THR A 1 69  ? -18.31681 -17.08894 13.05029  1.000 44.23942  ? 69  THR A HG21 1 
ATOM   1075 H HG22 . THR A 1 69  ? -18.33361 -18.34355 14.00850  1.000 44.23942  ? 69  THR A HG22 1 
ATOM   1076 H HG23 . THR A 1 69  ? -18.16795 -18.54195 12.45103  1.000 44.23942  ? 69  THR A HG23 1 
ATOM   1077 N N    . GLY A 1 70  ? -22.89701 -19.14909 13.90969  1.000 32.80737  ? 70  GLY A N    1 
ATOM   1078 C CA   . GLY A 1 70  ? -24.32898 -19.13055 13.66935  1.000 32.37127  ? 70  GLY A CA   1 
ATOM   1079 C C    . GLY A 1 70  ? -24.70659 -18.05947 12.66145  1.000 42.14454  ? 70  GLY A C    1 
ATOM   1080 O O    . GLY A 1 70  ? -24.23092 -16.92354 12.71967  1.000 39.90200  ? 70  GLY A O    1 
ATOM   1081 H H    . GLY A 1 70  ? -22.65448 -18.82323 14.66771  1.000 38.57614  ? 70  GLY A H    1 
ATOM   1082 H HA2  . GLY A 1 70  ? -24.61250 -19.99246 13.32637  1.000 39.00406  ? 70  GLY A HA2  1 
ATOM   1083 H HA3  . GLY A 1 70  ? -24.79610 -18.95225 14.50056  1.000 39.00406  ? 70  GLY A HA3  1 
ATOM   1084 N N    . MET A 1 71  ? -25.56996 -18.43049 11.72302  1.000 45.94775  ? 71  MET A N    1 
ATOM   1085 C CA   . MET A 1 71  ? -25.99898 -17.54107 10.65519  1.000 41.85489  ? 71  MET A CA   1 
ATOM   1086 C C    . MET A 1 71  ? -27.43886 -17.10223 10.87477  1.000 48.93725  ? 71  MET A C    1 
ATOM   1087 O O    . MET A 1 71  ? -28.22587 -17.76859 11.54926  1.000 54.24327  ? 71  MET A O    1 
ATOM   1088 C CB   . MET A 1 71  ? -25.86994 -18.22339 9.28847   1.000 49.70140  ? 71  MET A CB   1 
ATOM   1089 C CG   . MET A 1 71  ? -24.51538 -18.02970 8.63322   1.000 62.67518  ? 71  MET A CG   1 
ATOM   1090 S SD   . MET A 1 71  ? -24.39959 -18.82241 7.01894   1.000 72.49668  ? 71  MET A SD   1 
ATOM   1091 C CE   . MET A 1 71  ? -25.45554 -17.75622 6.04211   1.000 41.76779  ? 71  MET A CE   1 
ATOM   1092 H H    . MET A 1 71  ? -25.92837 -19.21130 11.68459  1.000 55.29584  ? 71  MET A H    1 
ATOM   1093 H HA   . MET A 1 71  ? -25.42875 -16.75638 10.65577  1.000 50.38441  ? 71  MET A HA   1 
ATOM   1094 H HB2  . MET A 1 71  ? -26.01055 -19.17647 9.40142   1.000 59.80022  ? 71  MET A HB2  1 
ATOM   1095 H HB3  . MET A 1 71  ? -26.54207 -17.85720 8.69261   1.000 59.80022  ? 71  MET A HB3  1 
ATOM   1096 H HG2  . MET A 1 71  ? -24.35555 -17.08053 8.51309   1.000 75.36876  ? 71  MET A HG2  1 
ATOM   1097 H HG3  . MET A 1 71  ? -23.83078 -18.41173 9.20443   1.000 75.36876  ? 71  MET A HG3  1 
ATOM   1098 H HE1  . MET A 1 71  ? -25.71829 -18.22562 5.23493   1.000 50.27989  ? 71  MET A HE1  1 
ATOM   1099 H HE2  . MET A 1 71  ? -26.24156 -17.52757 6.56250   1.000 50.27989  ? 71  MET A HE2  1 
ATOM   1100 H HE3  . MET A 1 71  ? -24.96552 -16.95134 5.81204   1.000 50.27989  ? 71  MET A HE3  1 
ATOM   1101 N N    . ILE A 1 72  ? -27.77195 -15.95279 10.28698  1.000 42.32762  ? 72  ILE A N    1 
ATOM   1102 C CA   . ILE A 1 72  ? -29.13373 -15.44057 10.34819  1.000 40.10518  ? 72  ILE A CA   1 
ATOM   1103 C C    . ILE A 1 72  ? -30.02582 -16.28248 9.44667   1.000 26.81741  ? 72  ILE A C    1 
ATOM   1104 O O    . ILE A 1 72  ? -29.69986 -16.53241 8.27933   1.000 40.48657  ? 72  ILE A O    1 
ATOM   1105 C CB   . ILE A 1 72  ? -29.16395 -13.95960 9.94292   1.000 43.11379  ? 72  ILE A CB   1 
ATOM   1106 C CG1  . ILE A 1 72  ? -28.51143 -13.10157 11.02932  1.000 45.25660  ? 72  ILE A CG1  1 
ATOM   1107 C CG2  . ILE A 1 72  ? -30.58864 -13.49906 9.68952   1.000 35.76606  ? 72  ILE A CG2  1 
ATOM   1108 C CD1  . ILE A 1 72  ? -27.49540 -12.11427 10.50150  1.000 58.84873  ? 72  ILE A CD1  1 
ATOM   1109 H H    . ILE A 1 72  ? -27.22666 -15.45339 9.84783   1.000 50.95168  ? 72  ILE A H    1 
ATOM   1110 H HA   . ILE A 1 72  ? -29.46460 -15.51287 11.25714  1.000 48.28476  ? 72  ILE A HA   1 
ATOM   1111 H HB   . ILE A 1 72  ? -28.66029 -13.85981 9.11995   1.000 51.89508  ? 72  ILE A HB   1 
ATOM   1112 H HG12 . ILE A 1 72  ? -29.20340 -12.59793 11.48585  1.000 54.46646  ? 72  ILE A HG12 1 
ATOM   1113 H HG13 . ILE A 1 72  ? -28.05758 -13.68572 11.65676  1.000 54.46646  ? 72  ILE A HG13 1 
ATOM   1114 H HG21 . ILE A 1 72  ? -30.61075 -12.52933 9.68368   1.000 43.07781  ? 72  ILE A HG21 1 
ATOM   1115 H HG22 . ILE A 1 72  ? -30.88341 -13.84182 8.83131   1.000 43.07781  ? 72  ILE A HG22 1 
ATOM   1116 H HG23 . ILE A 1 72  ? -31.16061 -13.83871 10.39550  1.000 43.07781  ? 72  ILE A HG23 1 
ATOM   1117 H HD11 . ILE A 1 72  ? -27.13595 -11.60374 11.24382  1.000 70.77701  ? 72  ILE A HD11 1 
ATOM   1118 H HD12 . ILE A 1 72  ? -26.78259 -12.60091 10.05880  1.000 70.77701  ? 72  ILE A HD12 1 
ATOM   1119 H HD13 . ILE A 1 72  ? -27.93096 -11.51947 9.87110   1.000 70.77701  ? 72  ILE A HD13 1 
ATOM   1120 N N    . LEU A 1 73  ? -31.15808 -16.72370 9.98772   1.000 40.31785  ? 73  LEU A N    1 
ATOM   1121 C CA   . LEU A 1 73  ? -32.14886 -17.50190 9.25495   1.000 36.50306  ? 73  LEU A CA   1 
ATOM   1122 C C    . LEU A 1 73  ? -33.48069 -16.76836 9.31159   1.000 35.90459  ? 73  LEU A C    1 
ATOM   1123 O O    . LEU A 1 73  ? -33.95502 -16.41959 10.39803  1.000 45.77566  ? 73  LEU A O    1 
ATOM   1124 C CB   . LEU A 1 73  ? -32.28078 -18.90875 9.84354   1.000 49.95153  ? 73  LEU A CB   1 
ATOM   1125 C CG   . LEU A 1 73  ? -33.35985 -19.82776 9.26571   1.000 36.53403  ? 73  LEU A CG   1 
ATOM   1126 C CD1  . LEU A 1 73  ? -33.07093 -20.17419 7.81370   1.000 33.63252  ? 73  LEU A CD1  1 
ATOM   1127 C CD2  . LEU A 1 73  ? -33.48102 -21.09090 10.11652  1.000 34.69669  ? 73  LEU A CD2  1 
ATOM   1128 H H    . LEU A 1 73  ? -31.38078 -16.57916 10.80571  1.000 48.53996  ? 73  LEU A H    1 
ATOM   1129 H HA   . LEU A 1 73  ? -31.88643 -17.58992 8.32528   1.000 43.96221  ? 73  LEU A HA   1 
ATOM   1130 H HB2  . LEU A 1 73  ? -31.43217 -19.36166 9.71845   1.000 60.10037  ? 73  LEU A HB2  1 
ATOM   1131 H HB3  . LEU A 1 73  ? -32.47088 -18.81588 10.79018  1.000 60.10037  ? 73  LEU A HB3  1 
ATOM   1132 H HG   . LEU A 1 73  ? -34.21159 -19.36392 9.28303   1.000 43.99938  ? 73  LEU A HG   1 
ATOM   1133 H HD11 . LEU A 1 73  ? -33.76593 -20.76619 7.48596   1.000 40.51756  ? 73  LEU A HD11 1 
ATOM   1134 H HD12 . LEU A 1 73  ? -33.05836 -19.35740 7.29064   1.000 40.51756  ? 73  LEU A HD12 1 
ATOM   1135 H HD13 . LEU A 1 73  ? -32.20849 -20.61484 7.75975   1.000 40.51756  ? 73  LEU A HD13 1 
ATOM   1136 H HD21 . LEU A 1 73  ? -34.17053 -21.66009 9.74035   1.000 41.79457  ? 73  LEU A HD21 1 
ATOM   1137 H HD22 . LEU A 1 73  ? -32.62998 -21.55633 10.11380  1.000 41.79457  ? 73  LEU A HD22 1 
ATOM   1138 H HD23 . LEU A 1 73  ? -33.71770 -20.83958 11.02301  1.000 41.79457  ? 73  LEU A HD23 1 
ATOM   1139 N N    . GLU A 1 74  ? -34.08023 -16.53722 8.14463   1.000 44.41106  ? 74  GLU A N    1 
ATOM   1140 C CA   . GLU A 1 74  ? -35.32720 -15.79251 8.04669   1.000 33.72703  ? 74  GLU A CA   1 
ATOM   1141 C C    . GLU A 1 74  ? -36.26884 -16.50372 7.08614   1.000 30.26348  ? 74  GLU A C    1 
ATOM   1142 O O    . GLU A 1 74  ? -35.85173 -17.33490 6.27651   1.000 42.41407  ? 74  GLU A O    1 
ATOM   1143 C CB   . GLU A 1 74  ? -35.08427 -14.35057 7.57695   1.000 43.49638  ? 74  GLU A CB   1 
ATOM   1144 C CG   . GLU A 1 74  ? -34.25670 -13.51511 8.53924   1.000 48.23715  ? 74  GLU A CG   1 
ATOM   1145 C CD   . GLU A 1 74  ? -34.03599 -12.09742 8.04442   1.000 45.67700  ? 74  GLU A CD   1 
ATOM   1146 O OE1  . GLU A 1 74  ? -34.06770 -11.87655 6.81537   1.000 60.32362  ? 74  GLU A OE1  1 
ATOM   1147 O OE2  . GLU A 1 74  ? -33.83482 -11.20185 8.88828   1.000 37.98542  ? 74  GLU A OE2  1 
ATOM   1148 H H    . GLU A 1 74  ? -33.77745 -16.80669 7.38614   1.000 53.45181  ? 74  GLU A H    1 
ATOM   1149 H HA   . GLU A 1 74  ? -35.75264 -15.76501 8.91798   1.000 40.63098  ? 74  GLU A HA   1 
ATOM   1150 H HB2  . GLU A 1 74  ? -34.61398 -14.37546 6.72895   1.000 52.35420  ? 74  GLU A HB2  1 
ATOM   1151 H HB3  . GLU A 1 74  ? -35.94204 -13.91101 7.46783   1.000 52.35420  ? 74  GLU A HB3  1 
ATOM   1152 H HG2  . GLU A 1 74  ? -34.71627 -13.46712 9.39212   1.000 58.04312  ? 74  GLU A HG2  1 
ATOM   1153 H HG3  . GLU A 1 74  ? -33.38820 -13.93173 8.65336   1.000 58.04312  ? 74  GLU A HG3  1 
ATOM   1154 N N    . GLU A 1 75  ? -37.55284 -16.16127 7.18111   1.000 40.97046  ? 75  GLU A N    1 
ATOM   1155 C CA   . GLU A 1 75  ? -38.58551 -16.75267 6.32965   1.000 40.82166  ? 75  GLU A CA   1 
ATOM   1156 C C    . GLU A 1 75  ? -38.59609 -16.01554 4.99544   1.000 34.79872  ? 75  GLU A C    1 
ATOM   1157 O O    . GLU A 1 75  ? -39.33409 -15.05016 4.79263   1.000 39.93409  ? 75  GLU A O    1 
ATOM   1158 C CB   . GLU A 1 75  ? -39.94709 -16.69686 7.01341   1.000 35.12427  ? 75  GLU A CB   1 
ATOM   1159 C CG   . GLU A 1 75  ? -41.12385 -16.93467 6.07558   1.000 53.91689  ? 75  GLU A CG   1 
ATOM   1160 C CD   . GLU A 1 75  ? -42.38974 -17.35171 6.80464   1.000 73.04940  ? 75  GLU A CD   1 
ATOM   1161 O OE1  . GLU A 1 75  ? -43.26974 -17.96244 6.16116   1.000 68.68281  ? 75  GLU A OE1  1 
ATOM   1162 O OE2  . GLU A 1 75  ? -42.50508 -17.07667 8.01803   1.000 46.59000  ? 75  GLU A OE2  1 
ATOM   1163 H H    . GLU A 1 75  ? -37.85554 -15.58061 7.73860   1.000 49.32309  ? 75  GLU A H    1 
ATOM   1164 H HA   . GLU A 1 75  ? -38.36552 -17.68230 6.16144   1.000 49.14454  ? 75  GLU A HA   1 
ATOM   1165 H HB2  . GLU A 1 75  ? -39.97677 -17.37898 7.70242   1.000 42.30766  ? 75  GLU A HB2  1 
ATOM   1166 H HB3  . GLU A 1 75  ? -40.05940 -15.81905 7.41056   1.000 42.30766  ? 75  GLU A HB3  1 
ATOM   1167 H HG2  . GLU A 1 75  ? -41.31315 -16.11460 5.59334   1.000 64.85881  ? 75  GLU A HG2  1 
ATOM   1168 H HG3  . GLU A 1 75  ? -40.89201 -17.64038 5.45179   1.000 64.85881  ? 75  GLU A HG3  1 
ATOM   1169 N N    . GLY A 1 76  ? -37.76719 -16.48308 4.06839   1.000 36.10384  ? 76  GLY A N    1 
ATOM   1170 C CA   . GLY A 1 76  ? -37.68859 -15.87629 2.75905   1.000 34.67949  ? 76  GLY A CA   1 
ATOM   1171 C C    . GLY A 1 76  ? -36.89788 -14.58115 2.76512   1.000 44.78814  ? 76  GLY A C    1 
ATOM   1172 O O    . GLY A 1 76  ? -36.28155 -14.18283 3.75902   1.000 32.92372  ? 76  GLY A O    1 
ATOM   1173 H H    . GLY A 1 76  ? -37.24018 -17.15359 4.17917   1.000 43.48314  ? 76  GLY A H    1 
ATOM   1174 H HA2  . GLY A 1 76  ? -37.25953 -16.49285 2.14532   1.000 41.77393  ? 76  GLY A HA2  1 
ATOM   1175 H HA3  . GLY A 1 76  ? -38.58449 -15.68533 2.44001   1.000 41.77393  ? 76  GLY A HA3  1 
ATOM   1176 N N    . ALA A 1 77  ? -36.92065 -13.91686 1.61602   1.000 41.04698  ? 77  ALA A N    1 
ATOM   1177 C CA   . ALA A 1 77  ? -36.26362 -12.63885 1.40757   1.000 36.20464  ? 77  ALA A CA   1 
ATOM   1178 C C    . ALA A 1 77  ? -37.27870 -11.59511 0.96354   1.000 38.29852  ? 77  ALA A C    1 
ATOM   1179 O O    . ALA A 1 77  ? -38.37418 -11.93765 0.50176   1.000 47.20275  ? 77  ALA A O    1 
ATOM   1180 C CB   . ALA A 1 77  ? -35.15574 -12.75271 0.35018   1.000 38.30278  ? 77  ALA A CB   1 
ATOM   1181 H H    . ALA A 1 77  ? -37.32880 -14.20160 0.91464   1.000 49.41492  ? 77  ALA A H    1 
ATOM   1182 H HA   . ALA A 1 77  ? -35.86056 -12.34658 2.24004   1.000 43.60411  ? 77  ALA A HA   1 
ATOM   1183 H HB1  . ALA A 1 77  ? -34.74066 -11.88389 0.23286   1.000 46.12188  ? 77  ALA A HB1  1 
ATOM   1184 H HB2  . ALA A 1 77  ? -34.49595 -13.39645 0.65213   1.000 46.12188  ? 77  ALA A HB2  1 
ATOM   1185 H HB3  . ALA A 1 77  ? -35.54714 -13.04803 -0.48678  1.000 46.12188  ? 77  ALA A HB3  1 
ATOM   1186 N N    . PRO A 1 78  ? -36.95233 -10.30964 1.09344   1.000 40.44385  ? 78  PRO A N    1 
ATOM   1187 C CA   . PRO A 1 78  ? -37.82813 -9.27744  0.52696   1.000 39.86002  ? 78  PRO A CA   1 
ATOM   1188 C C    . PRO A 1 78  ? -37.98682 -9.47800  -0.97230  1.000 34.10100  ? 78  PRO A C    1 
ATOM   1189 O O    . PRO A 1 78  ? -37.07560 -9.94693  -1.65857  1.000 34.71940  ? 78  PRO A O    1 
ATOM   1190 C CB   . PRO A 1 78  ? -37.09987 -7.96570  0.84652   1.000 48.87028  ? 78  PRO A CB   1 
ATOM   1191 C CG   . PRO A 1 78  ? -36.17436 -8.29198  1.97105   1.000 40.52952  ? 78  PRO A CG   1 
ATOM   1192 C CD   . PRO A 1 78  ? -35.78698 -9.73547  1.79195   1.000 34.82746  ? 78  PRO A CD   1 
ATOM   1193 H HA   . PRO A 1 78  ? -38.69613 -9.27434  0.95994   1.000 47.99056  ? 78  PRO A HA   1 
ATOM   1194 H HB2  . PRO A 1 78  ? -36.60561 -7.66587  0.06761   1.000 58.80288  ? 78  PRO A HB2  1 
ATOM   1195 H HB3  . PRO A 1 78  ? -37.74230 -7.28931  1.11237   1.000 58.80288  ? 78  PRO A HB3  1 
ATOM   1196 H HG2  . PRO A 1 78  ? -35.39245 -7.71974  1.92570   1.000 48.79397  ? 78  PRO A HG2  1 
ATOM   1197 H HG3  . PRO A 1 78  ? -36.63141 -8.16280  2.81682   1.000 48.79397  ? 78  PRO A HG3  1 
ATOM   1198 H HD2  . PRO A 1 78  ? -34.98583 -9.81418  1.25078   1.000 41.95149  ? 78  PRO A HD2  1 
ATOM   1199 H HD3  . PRO A 1 78  ? -35.65118 -10.16638 2.65031   1.000 41.95149  ? 78  PRO A HD3  1 
ATOM   1200 N N    . GLU A 1 79  ? -39.16400 -9.11975  -1.47849  1.000 50.92961  ? 79  GLU A N    1 
ATOM   1201 C CA   . GLU A 1 79  ? -39.44994 -9.31038  -2.89352  1.000 53.43391  ? 79  GLU A CA   1 
ATOM   1202 C C    . GLU A 1 79  ? -38.46727 -8.52008  -3.74880  1.000 48.12222  ? 79  GLU A C    1 
ATOM   1203 O O    . GLU A 1 79  ? -38.12638 -7.37467  -3.43977  1.000 52.23597  ? 79  GLU A O    1 
ATOM   1204 C CB   . GLU A 1 79  ? -40.88349 -8.88523  -3.21057  1.000 60.76994  ? 79  GLU A CB   1 
ATOM   1205 C CG   . GLU A 1 79  ? -41.94408 -9.86881  -2.74131  1.000 51.43724  ? 79  GLU A CG   1 
ATOM   1206 C CD   . GLU A 1 79  ? -42.08783 -9.90490  -1.23143  1.000 58.56611  ? 79  GLU A CD   1 
ATOM   1207 O OE1  . GLU A 1 79  ? -41.50141 -9.03547  -0.55059  1.000 58.44504  ? 79  GLU A OE1  1 
ATOM   1208 O OE2  . GLU A 1 79  ? -42.78824 -10.80491 -0.72300  1.000 52.05781  ? 79  GLU A OE2  1 
ATOM   1209 H H    . GLU A 1 79  ? -39.80641 -8.76803  -1.02770  1.000 61.27407  ? 79  GLU A H    1 
ATOM   1210 H HA   . GLU A 1 79  ? -39.35940 -10.25082 -3.11322  1.000 64.27923  ? 79  GLU A HA   1 
ATOM   1211 H HB2  . GLU A 1 79  ? -41.05793 -8.03535  -2.77676  1.000 73.08246  ? 79  GLU A HB2  1 
ATOM   1212 H HB3  . GLU A 1 79  ? -40.97371 -8.79173  -4.17183  1.000 73.08246  ? 79  GLU A HB3  1 
ATOM   1213 H HG2  . GLU A 1 79  ? -42.80065 -9.61278  -3.11765  1.000 61.88323  ? 79  GLU A HG2  1 
ATOM   1214 H HG3  . GLU A 1 79  ? -41.70312 -10.75947 -3.04057  1.000 61.88323  ? 79  GLU A HG3  1 
ATOM   1215 N N    . GLY A 1 80  ? -38.01208 -9.14346  -4.83497  1.000 49.76285  ? 80  GLY A N    1 
ATOM   1216 C CA   . GLY A 1 80  ? -37.03023 -8.54747  -5.71042  1.000 44.84348  ? 80  GLY A CA   1 
ATOM   1217 C C    . GLY A 1 80  ? -35.58922 -8.79125  -5.31799  1.000 39.94441  ? 80  GLY A C    1 
ATOM   1218 O O    . GLY A 1 80  ? -34.68775 -8.44545  -6.09289  1.000 49.27942  ? 80  GLY A O    1 
ATOM   1219 H H    . GLY A 1 80  ? -38.26691 -9.92653  -5.08290  1.000 59.87396  ? 80  GLY A H    1 
ATOM   1220 H HA2  . GLY A 1 80  ? -37.15647 -8.90212  -6.60439  1.000 53.97072  ? 80  GLY A HA2  1 
ATOM   1221 H HA3  . GLY A 1 80  ? -37.17280 -7.58817  -5.72819  1.000 53.97072  ? 80  GLY A HA3  1 
ATOM   1222 N N    . THR A 1 81  ? -35.34094 -9.37023  -4.14473  1.000 44.49835  ? 81  THR A N    1 
ATOM   1223 C CA   . THR A 1 81  ? -33.97506 -9.64666  -3.71912  1.000 56.39285  ? 81  THR A CA   1 
ATOM   1224 C C    . THR A 1 81  ? -33.32712 -10.66533 -4.64734  1.000 38.31361  ? 81  THR A C    1 
ATOM   1225 O O    . THR A 1 81  ? -33.88880 -11.73348 -4.90366  1.000 37.68182  ? 81  THR A O    1 
ATOM   1226 C CB   . THR A 1 81  ? -33.96173 -10.17130 -2.28106  1.000 63.58853  ? 81  THR A CB   1 
ATOM   1227 O OG1  . THR A 1 81  ? -34.52167 -9.18493  -1.40380  1.000 45.77268  ? 81  THR A OG1  1 
ATOM   1228 C CG2  . THR A 1 81  ? -32.53273 -10.51437 -1.83377  1.000 36.50854  ? 81  THR A CG2  1 
ATOM   1229 H H    . THR A 1 81  ? -35.94373 -9.61104  -3.58059  1.000 53.55657  ? 81  THR A H    1 
ATOM   1230 H HA   . THR A 1 81  ? -33.46091 -8.82470  -3.74956  1.000 67.82996  ? 81  THR A HA   1 
ATOM   1231 H HB   . THR A 1 81  ? -34.49067 -10.98282 -2.23048  1.000 76.46478  ? 81  THR A HB   1 
ATOM   1232 H HG1  . THR A 1 81  ? -35.32145 -9.03552  -1.61269  1.000 55.08576  ? 81  THR A HG1  1 
ATOM   1233 H HG21 . THR A 1 81  ? -32.51113 -10.65988 -0.87499  1.000 43.96879  ? 81  THR A HG21 1 
ATOM   1234 H HG22 . THR A 1 81  ? -32.22935 -11.31970 -2.28131  1.000 43.96879  ? 81  THR A HG22 1 
ATOM   1235 H HG23 . THR A 1 81  ? -31.93187 -9.78579  -2.05521  1.000 43.96879  ? 81  THR A HG23 1 
ATOM   1236 N N    . VAL A 1 82  ? -32.14103 -10.33046 -5.15101  1.000 41.28467  ? 82  VAL A N    1 
ATOM   1237 C CA   . VAL A 1 82  ? -31.35992 -11.27011 -5.95010  1.000 43.07656  ? 82  VAL A CA   1 
ATOM   1238 C C    . VAL A 1 82  ? -30.58217 -12.15018 -4.97589  1.000 41.23007  ? 82  VAL A C    1 
ATOM   1239 O O    . VAL A 1 82  ? -29.65553 -11.68815 -4.30573  1.000 52.16686  ? 82  VAL A O    1 
ATOM   1240 C CB   . VAL A 1 82  ? -30.42161 -10.55200 -6.92569  1.000 43.52270  ? 82  VAL A CB   1 
ATOM   1241 C CG1  . VAL A 1 82  ? -29.66387 -11.57076 -7.77521  1.000 53.84229  ? 82  VAL A CG1  1 
ATOM   1242 C CG2  . VAL A 1 82  ? -31.20238 -9.59018  -7.81913  1.000 33.90025  ? 82  VAL A CG2  1 
ATOM   1243 H H    . VAL A 1 82  ? -31.76695 -9.56358  -5.04347  1.000 49.70015  ? 82  VAL A H    1 
ATOM   1244 H HA   . VAL A 1 82  ? -31.95728 -11.82699 -6.47350  1.000 51.85042  ? 82  VAL A HA   1 
ATOM   1245 H HB   . VAL A 1 82  ? -29.77862 -10.03388 -6.41675  1.000 52.38579  ? 82  VAL A HB   1 
ATOM   1246 H HG11 . VAL A 1 82  ? -29.17897 -11.10219 -8.47250  1.000 64.76929  ? 82  VAL A HG11 1 
ATOM   1247 H HG12 . VAL A 1 82  ? -29.04299 -12.05494 -7.20866  1.000 64.76929  ? 82  VAL A HG12 1 
ATOM   1248 H HG13 . VAL A 1 82  ? -30.29973 -12.18695 -8.17132  1.000 64.76929  ? 82  VAL A HG13 1 
ATOM   1249 H HG21 . VAL A 1 82  ? -30.59589 -9.19762  -8.46641  1.000 40.46750  ? 82  VAL A HG21 1 
ATOM   1250 H HG22 . VAL A 1 82  ? -31.90190 -10.08195 -8.27710  1.000 40.46750  ? 82  VAL A HG22 1 
ATOM   1251 H HG23 . VAL A 1 82  ? -31.59364 -8.89439  -7.26805  1.000 40.46750  ? 82  VAL A HG23 1 
ATOM   1252 N N    . ALA A 1 83  ? -30.97500 -13.41210 -4.88028  1.000 47.22670  ? 83  ALA A N    1 
ATOM   1253 C CA   . ALA A 1 83  ? -30.37946 -14.35068 -3.94581  1.000 30.91724  ? 83  ALA A CA   1 
ATOM   1254 C C    . ALA A 1 83  ? -29.36337 -15.23191 -4.65751  1.000 48.99815  ? 83  ALA A C    1 
ATOM   1255 O O    . ALA A 1 83  ? -29.30572 -15.30058 -5.88704  1.000 39.76852  ? 83  ALA A O    1 
ATOM   1256 C CB   . ALA A 1 83  ? -31.46332 -15.20961 -3.29019  1.000 41.41774  ? 83  ALA A CB   1 
ATOM   1257 H H    . ALA A 1 83  ? -31.60118 -13.75583 -5.35919  1.000 56.83058  ? 83  ALA A H    1 
ATOM   1258 H HA   . ALA A 1 83  ? -29.91924 -13.85851 -3.24806  1.000 37.25923  ? 83  ALA A HA   1 
ATOM   1259 H HB1  . ALA A 1 83  ? -31.04404 -15.83322 -2.67683  1.000 49.85983  ? 83  ALA A HB1  1 
ATOM   1260 H HB2  . ALA A 1 83  ? -32.07519 -14.63193 -2.80770  1.000 49.85983  ? 83  ALA A HB2  1 
ATOM   1261 H HB3  . ALA A 1 83  ? -31.94167 -15.69538 -3.98019  1.000 49.85983  ? 83  ALA A HB3  1 
ATOM   1262 N N    . THR A 1 84  ? -28.54790 -15.91065 -3.85661  1.000 39.52584  ? 84  THR A N    1 
ATOM   1263 C CA   . THR A 1 84  ? -27.58940 -16.88755 -4.34896  1.000 42.18154  ? 84  THR A CA   1 
ATOM   1264 C C    . THR A 1 84  ? -28.06396 -18.27742 -3.95010  1.000 35.49099  ? 84  THR A C    1 
ATOM   1265 O O    . THR A 1 84  ? -28.31979 -18.53661 -2.76902  1.000 29.93177  ? 84  THR A O    1 
ATOM   1266 C CB   . THR A 1 84  ? -26.18907 -16.62857 -3.79259  1.000 40.17102  ? 84  THR A CB   1 
ATOM   1267 O OG1  . THR A 1 84  ? -25.80653 -15.27255 -4.05280  1.000 46.50368  ? 84  THR A OG1  1 
ATOM   1268 C CG2  . THR A 1 84  ? -25.18563 -17.55387 -4.44809  1.000 36.95970  ? 84  THR A CG2  1 
ATOM   1269 H H    . THR A 1 84  ? -28.53293 -15.81814 -3.00173  1.000 47.58955  ? 84  THR A H    1 
ATOM   1270 H HA   . THR A 1 84  ? -27.53724 -16.83459 -5.31611  1.000 50.77639  ? 84  THR A HA   1 
ATOM   1271 H HB   . THR A 1 84  ? -26.18850 -16.78843 -2.83585  1.000 48.36376  ? 84  THR A HB   1 
ATOM   1272 H HG1  . THR A 1 84  ? -25.02781 -15.13437 -3.76979  1.000 55.96296  ? 84  THR A HG1  1 
ATOM   1273 H HG21 . THR A 1 84  ? -24.30522 -17.41251 -4.06625  1.000 44.51018  ? 84  THR A HG21 1 
ATOM   1274 H HG22 . THR A 1 84  ? -25.44512 -18.47787 -4.30738  1.000 44.51018  ? 84  THR A HG22 1 
ATOM   1275 H HG23 . THR A 1 84  ? -25.14697 -17.37944 -5.40149  1.000 44.51018  ? 84  THR A HG23 1 
ATOM   1276 N N    . LEU A 1 85  ? -28.19274 -19.15695 -4.93616  1.000 31.59291  ? 85  LEU A N    1 
ATOM   1277 C CA   . LEU A 1 85  ? -28.55425 -20.55730 -4.72169  1.000 41.26661  ? 85  LEU A CA   1 
ATOM   1278 C C    . LEU A 1 85  ? -27.26372 -21.36863 -4.79300  1.000 36.01996  ? 85  LEU A C    1 
ATOM   1279 O O    . LEU A 1 85  ? -26.71574 -21.59305 -5.87506  1.000 34.35924  ? 85  LEU A O    1 
ATOM   1280 C CB   . LEU A 1 85  ? -29.57972 -20.99845 -5.75729  1.000 48.42736  ? 85  LEU A CB   1 
ATOM   1281 C CG   . LEU A 1 85  ? -30.01800 -22.46097 -5.76500  1.000 42.90843  ? 85  LEU A CG   1 
ATOM   1282 C CD1  . LEU A 1 85  ? -30.49458 -22.88992 -4.39480  1.000 30.65088  ? 85  LEU A CD1  1 
ATOM   1283 C CD2  . LEU A 1 85  ? -31.10980 -22.66819 -6.80500  1.000 37.43234  ? 85  LEU A CD2  1 
ATOM   1284 H H    . LEU A 1 85  ? -28.07241 -18.96228 -5.76515  1.000 38.07003  ? 85  LEU A H    1 
ATOM   1285 H HA   . LEU A 1 85  ? -28.94504 -20.68262 -3.84278  1.000 49.67847  ? 85  LEU A HA   1 
ATOM   1286 H HB2  . LEU A 1 85  ? -30.38124 -20.46964 -5.62009  1.000 58.27137  ? 85  LEU A HB2  1 
ATOM   1287 H HB3  . LEU A 1 85  ? -29.20793 -20.81590 -6.63442  1.000 58.27137  ? 85  LEU A HB3  1 
ATOM   1288 H HG   . LEU A 1 85  ? -29.26026 -23.02026 -5.99723  1.000 51.64866  ? 85  LEU A HG   1 
ATOM   1289 H HD11 . LEU A 1 85  ? -31.20545 -23.54185 -4.49748  1.000 36.93960  ? 85  LEU A HD11 1 
ATOM   1290 H HD12 . LEU A 1 85  ? -29.75179 -23.28389 -3.91111  1.000 36.93960  ? 85  LEU A HD12 1 
ATOM   1291 H HD13 . LEU A 1 85  ? -30.82495 -22.11266 -3.91772  1.000 36.93960  ? 85  LEU A HD13 1 
ATOM   1292 H HD21 . LEU A 1 85  ? -31.34795 -23.60817 -6.82987  1.000 45.07735  ? 85  LEU A HD21 1 
ATOM   1293 H HD22 . LEU A 1 85  ? -31.88383 -22.13721 -6.56038  1.000 45.07735  ? 85  LEU A HD22 1 
ATOM   1294 H HD23 . LEU A 1 85  ? -30.77721 -22.38817 -7.67211  1.000 45.07735  ? 85  LEU A HD23 1 
ATOM   1295 N N    . LEU A 1 86  ? -26.77287 -21.80203 -3.63160  1.000 30.91223  ? 86  LEU A N    1 
ATOM   1296 C CA   . LEU A 1 86  ? -25.47015 -22.46060 -3.53014  1.000 47.76307  ? 86  LEU A CA   1 
ATOM   1297 C C    . LEU A 1 86  ? -25.65111 -23.94496 -3.81488  1.000 36.15045  ? 86  LEU A C    1 
ATOM   1298 O O    . LEU A 1 86  ? -25.96717 -24.73804 -2.92824  1.000 31.45977  ? 86  LEU A O    1 
ATOM   1299 C CB   . LEU A 1 86  ? -24.85482 -22.22795 -2.15573  1.000 30.44133  ? 86  LEU A CB   1 
ATOM   1300 C CG   . LEU A 1 86  ? -24.38535 -20.80783 -1.83685  1.000 44.02787  ? 86  LEU A CG   1 
ATOM   1301 C CD1  . LEU A 1 86  ? -25.56463 -19.86346 -1.67099  1.000 37.67871  ? 86  LEU A CD1  1 
ATOM   1302 C CD2  . LEU A 1 86  ? -23.50958 -20.80382 -0.58869  1.000 37.27818  ? 86  LEU A CD2  1 
ATOM   1303 H H    . LEU A 1 86  ? -27.18095 -21.72519 -2.87850  1.000 37.25321  ? 86  LEU A H    1 
ATOM   1304 H HA   . LEU A 1 86  ? -24.87881 -22.09076 -4.20426  1.000 57.47423  ? 86  LEU A HA   1 
ATOM   1305 H HB2  . LEU A 1 86  ? -25.51795 -22.46333 -1.48807  1.000 36.68813  ? 86  LEU A HB2  1 
ATOM   1306 H HB3  . LEU A 1 86  ? -24.08097 -22.80696 -2.07324  1.000 36.68813  ? 86  LEU A HB3  1 
ATOM   1307 H HG   . LEU A 1 86  ? -23.85469 -20.48207 -2.58060  1.000 52.99199  ? 86  LEU A HG   1 
ATOM   1308 H HD11 . LEU A 1 86  ? -25.25052 -19.03068 -1.28538  1.000 45.37299  ? 86  LEU A HD11 1 
ATOM   1309 H HD12 . LEU A 1 86  ? -25.96044 -19.69673 -2.54073  1.000 45.37299  ? 86  LEU A HD12 1 
ATOM   1310 H HD13 . LEU A 1 86  ? -26.21803 -20.27432 -1.08349  1.000 45.37299  ? 86  LEU A HD13 1 
ATOM   1311 H HD21 . LEU A 1 86  ? -23.18546 -19.90289 -0.43322  1.000 44.89235  ? 86  LEU A HD21 1 
ATOM   1312 H HD22 . LEU A 1 86  ? -24.03789 -21.10060 0.16875   1.000 44.89235  ? 86  LEU A HD22 1 
ATOM   1313 H HD23 . LEU A 1 86  ? -22.76122 -21.40548 -0.72606  1.000 44.89235  ? 86  LEU A HD23 1 
ATOM   1314 N N    . ILE A 1 87  ? -25.42938 -24.33059 -5.06769  1.000 29.16285  ? 87  ILE A N    1 
ATOM   1315 C CA   . ILE A 1 87  ? -25.65108 -25.69851 -5.51996  1.000 38.36935  ? 87  ILE A CA   1 
ATOM   1316 C C    . ILE A 1 87  ? -24.32077 -26.43140 -5.57035  1.000 41.70024  ? 87  ILE A C    1 
ATOM   1317 O O    . ILE A 1 87  ? -23.33603 -25.91944 -6.11640  1.000 46.72509  ? 87  ILE A O    1 
ATOM   1318 C CB   . ILE A 1 87  ? -26.35903 -25.73066 -6.88926  1.000 42.20237  ? 87  ILE A CB   1 
ATOM   1319 C CG1  . ILE A 1 87  ? -27.85139 -25.45108 -6.67383  1.000 38.41585  ? 87  ILE A CG1  1 
ATOM   1320 C CG2  . ILE A 1 87  ? -26.08817 -27.05374 -7.60167  1.000 34.65342  ? 87  ILE A CG2  1 
ATOM   1321 C CD1  . ILE A 1 87  ? -28.74698 -25.79212 -7.83398  1.000 57.55208  ? 87  ILE A CD1  1 
ATOM   1322 H H    . ILE A 1 87  ? -25.14422 -23.80581 -5.68647  1.000 35.15397  ? 87  ILE A H    1 
ATOM   1323 H HA   . ILE A 1 87  ? -26.21516 -26.15305 -4.87490  1.000 46.20177  ? 87  ILE A HA   1 
ATOM   1324 H HB   . ILE A 1 87  ? -26.00769 -25.03895 -7.47149  1.000 50.80138  ? 87  ILE A HB   1 
ATOM   1325 H HG12 . ILE A 1 87  ? -28.15297 -25.97208 -5.91324  1.000 46.25756  ? 87  ILE A HG12 1 
ATOM   1326 H HG13 . ILE A 1 87  ? -27.96164 -24.50461 -6.49232  1.000 46.25756  ? 87  ILE A HG13 1 
ATOM   1327 H HG21 . ILE A 1 87  ? -26.66611 -27.11849 -8.37801  1.000 41.74264  ? 87  ILE A HG21 1 
ATOM   1328 H HG22 . ILE A 1 87  ? -25.15876 -27.07904 -7.87817  1.000 41.74264  ? 87  ILE A HG22 1 
ATOM   1329 H HG23 . ILE A 1 87  ? -26.27158 -27.78462 -6.99088  1.000 41.74264  ? 87  ILE A HG23 1 
ATOM   1330 H HD11 . ILE A 1 87  ? -29.62381 -25.40697 -7.67994  1.000 69.22103  ? 87  ILE A HD11 1 
ATOM   1331 H HD12 . ILE A 1 87  ? -28.36357 -25.42722 -8.64684  1.000 69.22103  ? 87  ILE A HD12 1 
ATOM   1332 H HD13 . ILE A 1 87  ? -28.81743 -26.75691 -7.90559  1.000 69.22103  ? 87  ILE A HD13 1 
ATOM   1333 N N    . LYS A 1 88  ? -24.29804 -27.63370 -5.00573  1.000 38.73739  ? 88  LYS A N    1 
ATOM   1334 C CA   . LYS A 1 88  ? -23.13705 -28.50929 -5.02732  1.000 30.12752  ? 88  LYS A CA   1 
ATOM   1335 C C    . LYS A 1 88  ? -23.50789 -29.76420 -5.79950  1.000 38.34930  ? 88  LYS A C    1 
ATOM   1336 O O    . LYS A 1 88  ? -24.56042 -30.36090 -5.54708  1.000 32.91849  ? 88  LYS A O    1 
ATOM   1337 C CB   . LYS A 1 88  ? -22.69644 -28.86781 -3.61038  1.000 39.72608  ? 88  LYS A CB   1 
ATOM   1338 C CG   . LYS A 1 88  ? -21.19514 -28.88510 -3.41251  1.000 39.76500  ? 88  LYS A CG   1 
ATOM   1339 C CD   . LYS A 1 88  ? -20.84349 -29.28896 -1.98894  1.000 39.81441  ? 88  LYS A CD   1 
ATOM   1340 C CE   . LYS A 1 88  ? -20.15312 -28.16123 -1.23593  1.000 39.25966  ? 88  LYS A CE   1 
ATOM   1341 N NZ   . LYS A 1 88  ? -19.60912 -28.62765 0.07156   1.000 35.20343  ? 88  LYS A NZ   1 
ATOM   1342 H H    . LYS A 1 88  ? -24.96892 -27.97465 -4.58948  1.000 46.64341  ? 88  LYS A H    1 
ATOM   1343 H HA   . LYS A 1 88  ? -22.39232 -28.07314 -5.47010  1.000 36.31156  ? 88  LYS A HA   1 
ATOM   1344 H HB2  . LYS A 1 88  ? -23.06666 -28.21482 -2.99602  1.000 47.82984  ? 88  LYS A HB2  1 
ATOM   1345 H HB3  . LYS A 1 88  ? -23.03166 -29.75243 -3.39596  1.000 47.82984  ? 88  LYS A HB3  1 
ATOM   1346 H HG2  . LYS A 1 88  ? -20.79527 -29.52516 -4.02187  1.000 47.87654  ? 88  LYS A HG2  1 
ATOM   1347 H HG3  . LYS A 1 88  ? -20.83608 -27.99952 -3.57898  1.000 47.87654  ? 88  LYS A HG3  1 
ATOM   1348 H HD2  . LYS A 1 88  ? -21.65578 -29.51998 -1.51175  1.000 47.93583  ? 88  LYS A HD2  1 
ATOM   1349 H HD3  . LYS A 1 88  ? -20.24368 -30.05095 -2.01120  1.000 47.93583  ? 88  LYS A HD3  1 
ATOM   1350 H HE2  . LYS A 1 88  ? -19.41677 -27.82304 -1.76915  1.000 47.27013  ? 88  LYS A HE2  1 
ATOM   1351 H HE3  . LYS A 1 88  ? -20.79192 -27.45169 -1.06454  1.000 47.27013  ? 88  LYS A HE3  1 
ATOM   1352 H HZ1  . LYS A 1 88  ? -20.27057 -28.92347 0.58836   1.000 42.40266  ? 88  LYS A HZ1  1 
ATOM   1353 H HZ2  . LYS A 1 88  ? -19.02716 -29.28822 -0.05910  1.000 42.40266  ? 88  LYS A HZ2  1 
ATOM   1354 H HZ3  . LYS A 1 88  ? -19.19645 -27.95695 0.48624   1.000 42.40266  ? 88  LYS A HZ3  1 
ATOM   1355 N N    . ARG A 1 89  ? -22.66214 -30.16380 -6.72622  1.000 29.69712  ? 89  ARG A N    1 
ATOM   1356 C CA   . ARG A 1 89  ? -22.96589 -31.34407 -7.52223  1.000 43.13996  ? 89  ARG A CA   1 
ATOM   1357 C C    . ARG A 1 89  ? -22.16851 -32.54242 -7.03460  1.000 29.20590  ? 89  ARG A C    1 
ATOM   1358 O O    . ARG A 1 89  ? -21.12139 -32.39283 -6.39791  1.000 35.74644  ? 89  ARG A O    1 
ATOM   1359 C CB   . ARG A 1 89  ? -22.68500 -31.06205 -9.00044  1.000 44.81455  ? 89  ARG A CB   1 
ATOM   1360 C CG   . ARG A 1 89  ? -23.69612 -30.09783 -9.62453  1.000 32.49978  ? 89  ARG A CG   1 
ATOM   1361 C CD   . ARG A 1 89  ? -25.03841 -30.78820 -9.83510  1.000 41.72690  ? 89  ARG A CD   1 
ATOM   1362 N NE   . ARG A 1 89  ? -26.15902 -29.85603 -9.88540  1.000 32.21778  ? 89  ARG A NE   1 
ATOM   1363 C CZ   . ARG A 1 89  ? -26.48616 -29.13083 -10.94611 1.000 45.42672  ? 89  ARG A CZ   1 
ATOM   1364 N NH1  . ARG A 1 89  ? -25.76474 -29.16388 -12.05431 1.000 40.19841  ? 89  ARG A NH1  1 
ATOM   1365 N NH2  . ARG A 1 89  ? -27.56240 -28.35128 -10.89242 1.000 52.36317  ? 89  ARG A NH2  1 
ATOM   1366 H H    . ARG A 1 89  ? -21.91693 -29.77726 -6.91290  1.000 35.79509  ? 89  ARG A H    1 
ATOM   1367 H HA   . ARG A 1 89  ? -23.90532 -31.57151 -7.44077  1.000 51.92650  ? 89  ARG A HA   1 
ATOM   1368 H HB2  . ARG A 1 89  ? -21.80298 -30.66713 -9.08393  1.000 53.93600  ? 89  ARG A HB2  1 
ATOM   1369 H HB3  . ARG A 1 89  ? -22.72282 -31.89666 -9.49329  1.000 53.93600  ? 89  ARG A HB3  1 
ATOM   1370 H HG2  . ARG A 1 89  ? -23.82855 -29.33964 -9.03419  1.000 39.15828  ? 89  ARG A HG2  1 
ATOM   1371 H HG3  . ARG A 1 89  ? -23.36691 -29.79468 -10.48513 1.000 39.15828  ? 89  ARG A HG3  1 
ATOM   1372 H HD2  . ARG A 1 89  ? -25.01524 -31.27255 -10.67520 1.000 50.23082  ? 89  ARG A HD2  1 
ATOM   1373 H HD3  . ARG A 1 89  ? -25.19475 -31.40344 -9.10165  1.000 50.23082  ? 89  ARG A HD3  1 
ATOM   1374 H HE   . ARG A 1 89  ? -26.64090 -29.77087 -9.17820  1.000 38.81987  ? 89  ARG A HE   1 
ATOM   1375 H HH11 . ARG A 1 89  ? -25.06618 -29.66360 -12.09790 1.000 48.39663  ? 89  ARG A HH11 1 
ATOM   1376 H HH12 . ARG A 1 89  ? -25.99425 -28.68565 -12.73122 1.000 48.39663  ? 89  ARG A HH12 1 
ATOM   1377 H HH21 . ARG A 1 89  ? -28.03675 -28.32189 -10.17567 1.000 62.99434  ? 89  ARG A HH21 1 
ATOM   1378 H HH22 . ARG A 1 89  ? -27.78398 -27.87659 -11.57446 1.000 62.99434  ? 89  ARG A HH22 1 
ATOM   1379 N N    . PRO A 1 90  ? -22.65727 -33.75998 -7.29419  1.000 48.15828  ? 90  PRO A N    1 
ATOM   1380 C CA   . PRO A 1 90  ? -21.95057 -34.96289 -6.79901  1.000 45.50284  ? 90  PRO A CA   1 
ATOM   1381 C C    . PRO A 1 90  ? -20.51076 -35.02699 -7.23160  1.000 45.63506  ? 90  PRO A C    1 
ATOM   1382 O O    . PRO A 1 90  ? -19.70464 -35.71608 -6.58088  1.000 57.62575  ? 90  PRO A O    1 
ATOM   1383 C CB   . PRO A 1 90  ? -22.76646 -36.12007 -7.39911  1.000 40.31714  ? 90  PRO A CB   1 
ATOM   1384 C CG   . PRO A 1 90  ? -24.12471 -35.55056 -7.59969  1.000 36.29612  ? 90  PRO A CG   1 
ATOM   1385 C CD   . PRO A 1 90  ? -23.91410 -34.10783 -7.98208  1.000 47.99540  ? 90  PRO A CD   1 
ATOM   1386 H HA   . PRO A 1 90  ? -21.99858 -35.00562 -5.83114  1.000 54.76194  ? 90  PRO A HA   1 
ATOM   1387 H HB2  . PRO A 1 90  ? -22.37684 -36.39928 -8.24239  1.000 48.53910  ? 90  PRO A HB2  1 
ATOM   1388 H HB3  . PRO A 1 90  ? -22.78880 -36.86691 -6.78054  1.000 48.53910  ? 90  PRO A HB3  1 
ATOM   1389 H HG2  . PRO A 1 90  ? -24.57943 -36.03110 -8.30906  1.000 43.71389  ? 90  PRO A HG2  1 
ATOM   1390 H HG3  . PRO A 1 90  ? -24.63223 -35.61698 -6.77573  1.000 43.71389  ? 90  PRO A HG3  1 
ATOM   1391 H HD2  . PRO A 1 90  ? -23.81980 -34.01481 -8.94300  1.000 57.75302  ? 90  PRO A HD2  1 
ATOM   1392 H HD3  . PRO A 1 90  ? -24.64606 -33.55561 -7.66556  1.000 57.75302  ? 90  PRO A HD3  1 
ATOM   1393 N N    . THR A 1 91  ? -20.15322 -34.34919 -8.31775  1.000 41.98747  ? 91  THR A N    1 
ATOM   1394 C CA   . THR A 1 91  ? -18.76641 -34.24867 -8.73175  1.000 46.66327  ? 91  THR A CA   1 
ATOM   1395 C C    . THR A 1 91  ? -17.95961 -33.33515 -7.82239  1.000 45.02481  ? 91  THR A C    1 
ATOM   1396 O O    . THR A 1 91  ? -16.73934 -33.24096 -7.99180  1.000 34.32186  ? 91  THR A O    1 
ATOM   1397 C CB   . THR A 1 91  ? -18.67535 -33.72102 -10.16461 1.000 44.27261  ? 91  THR A CB   1 
ATOM   1398 O OG1  . THR A 1 91  ? -19.13278 -32.36295 -10.20303 1.000 49.82451  ? 91  THR A OG1  1 
ATOM   1399 C CG2  . THR A 1 91  ? -19.52052 -34.55814 -11.11004 1.000 43.70824  ? 91  THR A CG2  1 
ATOM   1400 H H    . THR A 1 91  ? -20.70251 -33.93590 -8.83454  1.000 50.54350  ? 91  THR A H    1 
ATOM   1401 H HA   . THR A 1 91  ? -18.37660 -35.13666 -8.71132  1.000 56.15446  ? 91  THR A HA   1 
ATOM   1402 H HB   . THR A 1 91  ? -17.75347 -33.76750 -10.46273 1.000 53.28567  ? 91  THR A HB   1 
ATOM   1403 H HG1  . THR A 1 91  ? -19.05220 -32.05453 -10.98019 1.000 59.94795  ? 91  THR A HG1  1 
ATOM   1404 H HG21 . THR A 1 91  ? -19.34750 -34.29792 -12.02833 1.000 52.60843  ? 91  THR A HG21 1 
ATOM   1405 H HG22 . THR A 1 91  ? -19.30549 -35.49796 -11.00332 1.000 52.60843  ? 91  THR A HG22 1 
ATOM   1406 H HG23 . THR A 1 91  ? -20.46216 -34.42684 -10.91773 1.000 52.60843  ? 91  THR A HG23 1 
ATOM   1407 N N    . GLY A 1 92  ? -18.61079 -32.65540 -6.87907  1.000 30.00732  ? 92  GLY A N    1 
ATOM   1408 C CA   . GLY A 1 92  ? -17.96268 -31.66551 -6.05442  1.000 31.41665  ? 92  GLY A CA   1 
ATOM   1409 C C    . GLY A 1 92  ? -17.91394 -30.27292 -6.64499  1.000 33.47198  ? 92  GLY A C    1 
ATOM   1410 O O    . GLY A 1 92  ? -17.46899 -29.34498 -5.95761  1.000 39.04052  ? 92  GLY A O    1 
ATOM   1411 H H    . GLY A 1 92  ? -19.44586 -32.75913 -6.70163  1.000 36.14831  ? 92  GLY A H    1 
ATOM   1412 H HA2  . GLY A 1 92  ? -18.43339 -31.61085 -5.20805  1.000 37.85852  ? 92  GLY A HA2  1 
ATOM   1413 H HA3  . GLY A 1 92  ? -17.04955 -31.94858 -5.89023  1.000 37.85852  ? 92  GLY A HA3  1 
ATOM   1414 N N    . GLU A 1 93  ? -18.35349 -30.08939 -7.88922  1.000 33.55137  ? 93  GLU A N    1 
ATOM   1415 C CA   . GLU A 1 93  ? -18.29056 -28.76830 -8.49864  1.000 33.67732  ? 93  GLU A CA   1 
ATOM   1416 C C    . GLU A 1 93  ? -19.17833 -27.79507 -7.73295  1.000 36.79285  ? 93  GLU A C    1 
ATOM   1417 O O    . GLU A 1 93  ? -20.24295 -28.16160 -7.22427  1.000 37.51258  ? 93  GLU A O    1 
ATOM   1418 C CB   . GLU A 1 93  ? -18.71277 -28.82138 -9.96711  1.000 39.94526  ? 93  GLU A CB   1 
ATOM   1419 C CG   . GLU A 1 93  ? -18.05734 -27.73077 -10.81133 1.000 62.44787  ? 93  GLU A CG   1 
ATOM   1420 C CD   . GLU A 1 93  ? -18.68688 -27.56964 -12.17991 1.000 53.23346  ? 93  GLU A CD   1 
ATOM   1421 O OE1  . GLU A 1 93  ? -18.72595 -28.55552 -12.94388 1.000 65.14697  ? 93  GLU A OE1  1 
ATOM   1422 O OE2  . GLU A 1 93  ? -19.14619 -26.45008 -12.49049 1.000 79.31354  ? 93  GLU A OE2  1 
ATOM   1423 H H    . GLU A 1 93  ? -18.68623 -30.70353 -8.39093  1.000 40.42018  ? 93  GLU A H    1 
ATOM   1424 H HA   . GLU A 1 93  ? -17.37528 -28.44848 -8.46898  1.000 40.57132  ? 93  GLU A HA   1 
ATOM   1425 H HB2  . GLU A 1 93  ? -18.45864 -29.68110 -10.33753 1.000 48.09285  ? 93  GLU A HB2  1 
ATOM   1426 H HB3  . GLU A 1 93  ? -19.67438 -28.70716 -10.02319 1.000 48.09285  ? 93  GLU A HB3  1 
ATOM   1427 H HG2  . GLU A 1 93  ? -18.13700 -26.88346 -10.34589 1.000 75.09599  ? 93  GLU A HG2  1 
ATOM   1428 H HG3  . GLU A 1 93  ? -17.12169 -27.95258 -10.93880 1.000 75.09599  ? 93  GLU A HG3  1 
ATOM   1429 N N    . LEU A 1 94  ? -18.72589 -26.54904 -7.64322  1.000 46.43874  ? 94  LEU A N    1 
ATOM   1430 C CA   . LEU A 1 94  ? -19.45184 -25.49171 -6.95350  1.000 49.28971  ? 94  LEU A CA   1 
ATOM   1431 C C    . LEU A 1 94  ? -20.17321 -24.64242 -7.98929  1.000 28.19326  ? 94  LEU A C    1 
ATOM   1432 O O    . LEU A 1 94  ? -19.56043 -24.18124 -8.95890  1.000 43.97430  ? 94  LEU A O    1 
ATOM   1433 C CB   . LEU A 1 94  ? -18.50196 -24.64226 -6.11070  1.000 44.82450  ? 94  LEU A CB   1 
ATOM   1434 C CG   . LEU A 1 94  ? -17.65847 -25.44543 -5.11422  1.000 45.85831  ? 94  LEU A CG   1 
ATOM   1435 C CD1  . LEU A 1 94  ? -16.90948 -24.52435 -4.15981  1.000 46.47788  ? 94  LEU A CD1  1 
ATOM   1436 C CD2  . LEU A 1 94  ? -18.52070 -26.44319 -4.34141  1.000 42.58132  ? 94  LEU A CD2  1 
ATOM   1437 H H    . LEU A 1 94  ? -17.98106 -26.28594 -7.98322  1.000 55.88503  ? 94  LEU A H    1 
ATOM   1438 H HA   . LEU A 1 94  ? -20.11296 -25.87054 -6.35324  1.000 59.30619  ? 94  LEU A HA   1 
ATOM   1439 H HB2  . LEU A 1 94  ? -17.89281 -24.17692 -6.70509  1.000 53.94794  ? 94  LEU A HB2  1 
ATOM   1440 H HB3  . LEU A 1 94  ? -19.02589 -24.00166 -5.60471  1.000 53.94794  ? 94  LEU A HB3  1 
ATOM   1441 H HG   . LEU A 1 94  ? -16.99836 -25.95100 -5.61376  1.000 55.18851  ? 94  LEU A HG   1 
ATOM   1442 H HD11 . LEU A 1 94  ? -16.48814 -25.05998 -3.46954  1.000 55.93200  ? 94  LEU A HD11 1 
ATOM   1443 H HD12 . LEU A 1 94  ? -16.23511 -24.03541 -4.65687  1.000 55.93200  ? 94  LEU A HD12 1 
ATOM   1444 H HD13 . LEU A 1 94  ? -17.53934 -23.90480 -3.75941  1.000 55.93200  ? 94  LEU A HD13 1 
ATOM   1445 H HD21 . LEU A 1 94  ? -18.01390 -26.77976 -3.58592  1.000 51.25613  ? 94  LEU A HD21 1 
ATOM   1446 H HD22 . LEU A 1 94  ? -19.32105 -25.99312 -4.02870  1.000 51.25613  ? 94  LEU A HD22 1 
ATOM   1447 H HD23 . LEU A 1 94  ? -18.76161 -27.17513 -4.93058  1.000 51.25613  ? 94  LEU A HD23 1 
ATOM   1448 N N    . MET A 1 95  ? -21.47534 -24.45417 -7.78956  1.000 39.56522  ? 95  MET A N    1 
ATOM   1449 C CA   . MET A 1 95  ? -22.35621 -23.85100 -8.78428  1.000 48.44601  ? 95  MET A CA   1 
ATOM   1450 C C    . MET A 1 95  ? -23.22652 -22.80446 -8.10491  1.000 37.40474  ? 95  MET A C    1 
ATOM   1451 O O    . MET A 1 95  ? -24.38660 -23.07260 -7.76276  1.000 35.30496  ? 95  MET A O    1 
ATOM   1452 C CB   . MET A 1 95  ? -23.22361 -24.91318 -9.46346  1.000 59.72728  ? 95  MET A CB   1 
ATOM   1453 C CG   . MET A 1 95  ? -22.49637 -25.76648 -10.48469 1.000 60.68810  ? 95  MET A CG   1 
ATOM   1454 S SD   . MET A 1 95  ? -23.06146 -25.42241 -12.16024 1.000 93.11093  ? 95  MET A SD   1 
ATOM   1455 C CE   . MET A 1 95  ? -24.75087 -26.01317 -12.06719 1.000 53.20761  ? 95  MET A CE   1 
ATOM   1456 H H    . MET A 1 95  ? -21.88201 -24.67445 -7.06451  1.000 47.63680  ? 95  MET A H    1 
ATOM   1457 H HA   . MET A 1 95  ? -21.80835 -23.41679 -9.45675  1.000 58.29375  ? 95  MET A HA   1 
ATOM   1458 H HB2  . MET A 1 95  ? -23.57307 -25.50790 -8.78149  1.000 71.83128  ? 95  MET A HB2  1 
ATOM   1459 H HB3  . MET A 1 95  ? -23.95377 -24.46813 -9.92139  1.000 71.83128  ? 95  MET A HB3  1 
ATOM   1460 H HG2  . MET A 1 95  ? -21.54556 -25.57988 -10.43937 1.000 72.98426  ? 95  MET A HG2  1 
ATOM   1461 H HG3  . MET A 1 95  ? -22.66002 -26.70341 -10.29422 1.000 72.98426  ? 95  MET A HG3  1 
ATOM   1462 H HE1  . MET A 1 95  ? -25.17903 -25.88230 -12.92768 1.000 64.00767  ? 95  MET A HE1  1 
ATOM   1463 H HE2  . MET A 1 95  ? -24.74357 -26.95650 -11.84142 1.000 64.00767  ? 95  MET A HE2  1 
ATOM   1464 H HE3  . MET A 1 95  ? -25.22310 -25.51301 -11.38328 1.000 64.00767  ? 95  MET A HE3  1 
ATOM   1465 N N    . PRO A 1 96  ? -22.70396 -21.59720 -7.89991  1.000 44.09902  ? 96  PRO A N    1 
ATOM   1466 C CA   . PRO A 1 96  ? -23.53908 -20.52141 -7.34801  1.000 35.42676  ? 96  PRO A CA   1 
ATOM   1467 C C    . PRO A 1 96  ? -24.43265 -19.94039 -8.43460  1.000 42.12238  ? 96  PRO A C    1 
ATOM   1468 O O    . PRO A 1 96  ? -23.95171 -19.50634 -9.48452  1.000 46.94130  ? 96  PRO A O    1 
ATOM   1469 C CB   . PRO A 1 96  ? -22.52077 -19.49328 -6.84493  1.000 46.04878  ? 96  PRO A CB   1 
ATOM   1470 C CG   . PRO A 1 96  ? -21.24471 -19.77986 -7.61168  1.000 41.36287  ? 96  PRO A CG   1 
ATOM   1471 C CD   . PRO A 1 96  ? -21.38273 -21.10314 -8.33162  1.000 41.62666  ? 96  PRO A CD   1 
ATOM   1472 H HA   . PRO A 1 96  ? -24.07670 -20.83545 -6.60421  1.000 42.67065  ? 96  PRO A HA   1 
ATOM   1473 H HB2  . PRO A 1 96  ? -22.84092 -18.59651 -7.02989  1.000 55.41708  ? 96  PRO A HB2  1 
ATOM   1474 H HB3  . PRO A 1 96  ? -22.38366 -19.60651 -5.89137  1.000 55.41708  ? 96  PRO A HB3  1 
ATOM   1475 H HG2  . PRO A 1 96  ? -21.09825 -19.06749 -8.25353  1.000 49.79399  ? 96  PRO A HG2  1 
ATOM   1476 H HG3  . PRO A 1 96  ? -20.50509 -19.81933 -6.98534  1.000 49.79399  ? 96  PRO A HG3  1 
ATOM   1477 H HD2  . PRO A 1 96  ? -21.36042 -20.97570 -9.29296  1.000 50.11054  ? 96  PRO A HD2  1 
ATOM   1478 H HD3  . PRO A 1 96  ? -20.68121 -21.71633 -8.06187  1.000 50.11054  ? 96  PRO A HD3  1 
ATOM   1479 N N    . LEU A 1 97  ? -25.73634 -19.93378 -8.17833  1.000 49.99311  ? 97  LEU A N    1 
ATOM   1480 C CA   . LEU A 1 97  ? -26.72250 -19.46875 -9.14043  1.000 50.08879  ? 97  LEU A CA   1 
ATOM   1481 C C    . LEU A 1 97  ? -27.44166 -18.24000 -8.60608  1.000 38.16136  ? 97  LEU A C    1 
ATOM   1482 O O    . LEU A 1 97  ? -27.83673 -18.19549 -7.43679  1.000 36.08982  ? 97  LEU A O    1 
ATOM   1483 C CB   . LEU A 1 97  ? -27.74156 -20.56476 -9.45826  1.000 44.85549  ? 97  LEU A CB   1 
ATOM   1484 C CG   . LEU A 1 97  ? -27.23913 -21.72519 -10.31501 1.000 45.56407  ? 97  LEU A CG   1 
ATOM   1485 C CD1  . LEU A 1 97  ? -28.32865 -22.77311 -10.45891 1.000 53.51662  ? 97  LEU A CD1  1 
ATOM   1486 C CD2  . LEU A 1 97  ? -26.78708 -21.24613 -11.68125 1.000 39.06769  ? 97  LEU A CD2  1 
ATOM   1487 H H    . LEU A 1 97  ? -26.07934 -20.20055 -7.43618  1.000 60.15027  ? 97  LEU A H    1 
ATOM   1488 H HA   . LEU A 1 97  ? -26.27066 -19.21809 -9.96135  1.000 60.26508  ? 97  LEU A HA   1 
ATOM   1489 H HB2  . LEU A 1 97  ? -28.05107 -20.94116 -8.61955  1.000 53.98513  ? 97  LEU A HB2  1 
ATOM   1490 H HB3  . LEU A 1 97  ? -28.48325 -20.15835 -9.93327  1.000 53.98513  ? 97  LEU A HB3  1 
ATOM   1491 H HG   . LEU A 1 97  ? -26.47207 -22.12642 -9.87735  1.000 54.83542  ? 97  LEU A HG   1 
ATOM   1492 H HD11 . LEU A 1 97  ? -27.99768 -23.49909 -11.01054 1.000 64.37848  ? 97  LEU A HD11 1 
ATOM   1493 H HD12 . LEU A 1 97  ? -28.56391 -23.10694 -9.57907  1.000 64.37848  ? 97  LEU A HD12 1 
ATOM   1494 H HD13 . LEU A 1 97  ? -29.10411 -22.36708 -10.87689 1.000 64.37848  ? 97  LEU A HD13 1 
ATOM   1495 H HD21 . LEU A 1 97  ? -26.52218 -22.01289 -12.21305 1.000 47.03977  ? 97  LEU A HD21 1 
ATOM   1496 H HD22 . LEU A 1 97  ? -27.52196 -20.78252 -12.11243 1.000 47.03977  ? 97  LEU A HD22 1 
ATOM   1497 H HD23 . LEU A 1 97  ? -26.03473 -20.64375 -11.57169 1.000 47.03977  ? 97  LEU A HD23 1 
ATOM   1498 N N    . ALA A 1 98  ? -27.61000 -17.24747 -9.47438  1.000 44.85791  ? 98  ALA A N    1 
ATOM   1499 C CA   . ALA A 1 98  ? -28.31505 -16.02224 -9.13050  1.000 31.33855  ? 98  ALA A CA   1 
ATOM   1500 C C    . ALA A 1 98  ? -29.80483 -16.22073 -9.37338  1.000 33.82021  ? 98  ALA A C    1 
ATOM   1501 O O    . ALA A 1 98  ? -30.20851 -16.69687 -10.43996 1.000 42.81463  ? 98  ALA A O    1 
ATOM   1502 C CB   . ALA A 1 98  ? -27.78442 -14.84807 -9.95147  1.000 44.38374  ? 98  ALA A CB   1 
ATOM   1503 H H    . ALA A 1 98  ? -27.31883 -17.26217 -10.28345 1.000 53.98803  ? 98  ALA A H    1 
ATOM   1504 H HA   . ALA A 1 98  ? -28.18017 -15.81198 -8.19322  1.000 37.76480  ? 98  ALA A HA   1 
ATOM   1505 H HB1  . ALA A 1 98  ? -28.27248 -14.04607 -9.70758  1.000 53.41903  ? 98  ALA A HB1  1 
ATOM   1506 H HB2  . ALA A 1 98  ? -26.84032 -14.73125 -9.76188  1.000 53.41903  ? 98  ALA A HB2  1 
ATOM   1507 H HB3  . ALA A 1 98  ? -27.91140 -15.03879 -10.89402 1.000 53.41903  ? 98  ALA A HB3  1 
ATOM   1508 N N    . ALA A 1 99  ? -30.61618 -15.87413 -8.37548  1.000 30.43983  ? 99  ALA A N    1 
ATOM   1509 C CA   . ALA A 1 99  ? -32.06329 -16.03778 -8.45472  1.000 39.67679  ? 99  ALA A CA   1 
ATOM   1510 C C    . ALA A 1 99  ? -32.72757 -14.81042 -7.85147  1.000 46.18497  ? 99  ALA A C    1 
ATOM   1511 O O    . ALA A 1 99  ? -32.49384 -14.48876 -6.68232  1.000 53.28788  ? 99  ALA A O    1 
ATOM   1512 C CB   . ALA A 1 99  ? -32.51386 -17.30876 -7.72753  1.000 29.24367  ? 99  ALA A CB   1 
ATOM   1513 H H    . ALA A 1 99  ? -30.34657 -15.53704 -7.63166  1.000 36.68633  ? 99  ALA A H    1 
ATOM   1514 H HA   . ALA A 1 99  ? -32.33221 -16.10313 -9.38441  1.000 47.77069  ? 99  ALA A HA   1 
ATOM   1515 H HB1  . ALA A 1 99  ? -33.47689 -17.39347 -7.80694  1.000 35.25094  ? 99  ALA A HB1  1 
ATOM   1516 H HB2  . ALA A 1 99  ? -32.07979 -18.07547 -8.13328  1.000 35.25094  ? 99  ALA A HB2  1 
ATOM   1517 H HB3  . ALA A 1 99  ? -32.26354 -17.24330 -6.79267  1.000 35.25094  ? 99  ALA A HB3  1 
ATOM   1518 N N    . ARG A 1 100 ? -33.54320 -14.12147 -8.64853  1.000 37.57002  ? 100 ARG A N    1 
ATOM   1519 C CA   . ARG A 1 100 ? -34.32200 -12.98739 -8.16044  1.000 39.55466  ? 100 ARG A CA   1 
ATOM   1520 C C    . ARG A 1 100 ? -35.55460 -13.52722 -7.44396  1.000 38.78528  ? 100 ARG A C    1 
ATOM   1521 O O    . ARG A 1 100 ? -36.43870 -14.11917 -8.07323  1.000 32.64213  ? 100 ARG A O    1 
ATOM   1522 C CB   . ARG A 1 100 ? -34.71021 -12.06112 -9.30878  1.000 34.46966  ? 100 ARG A CB   1 
ATOM   1523 C CG   . ARG A 1 100 ? -35.54721 -10.86830 -8.86987  1.000 51.72375  ? 100 ARG A CG   1 
ATOM   1524 C CD   . ARG A 1 100 ? -35.75067 -9.85287  -9.99099  1.000 44.33975  ? 100 ARG A CD   1 
ATOM   1525 N NE   . ARG A 1 100 ? -34.62431 -8.93582  -10.13503 1.000 56.35882  ? 100 ARG A NE   1 
ATOM   1526 C CZ   . ARG A 1 100 ? -33.80534 -8.89264  -11.17984 1.000 57.10181  ? 100 ARG A CZ   1 
ATOM   1527 N NH1  . ARG A 1 100 ? -33.94855 -9.71168  -12.20980 1.000 65.59324  ? 100 ARG A NH1  1 
ATOM   1528 N NH2  . ARG A 1 100 ? -32.82161 -7.99766  -11.19443 1.000 56.51507  ? 100 ARG A NH2  1 
ATOM   1529 H H    . ARG A 1 100 ? -33.66304 -14.29356 -9.48257  1.000 45.24256  ? 100 ARG A H    1 
ATOM   1530 H HA   . ARG A 1 100 ? -33.79087 -12.47287 -7.53269  1.000 47.62414  ? 100 ARG A HA   1 
ATOM   1531 H HB2  . ARG A 1 100 ? -33.90186 -11.72071 -9.72301  1.000 41.52214  ? 100 ARG A HB2  1 
ATOM   1532 H HB3  . ARG A 1 100 ? -35.22768 -12.56528 -9.95604  1.000 41.52214  ? 100 ARG A HB3  1 
ATOM   1533 H HG2  . ARG A 1 100 ? -36.42030 -11.18070 -8.58522  1.000 62.22704  ? 100 ARG A HG2  1 
ATOM   1534 H HG3  . ARG A 1 100 ? -35.09976 -10.41956 -8.13548  1.000 62.22704  ? 100 ARG A HG3  1 
ATOM   1535 H HD2  . ARG A 1 100 ? -35.86054 -10.32649 -10.83033 1.000 53.36624  ? 100 ARG A HD2  1 
ATOM   1536 H HD3  . ARG A 1 100 ? -36.54299 -9.32658  -9.80084  1.000 53.36624  ? 100 ARG A HD3  1 
ATOM   1537 H HE   . ARG A 1 100 ? -34.47982 -8.38081  -9.49418  1.000 67.78913  ? 100 ARG A HE   1 
ATOM   1538 H HH11 . ARG A 1 100 ? -34.58446 -10.29064 -12.21361 1.000 78.87043  ? 100 ARG A HH11 1 
ATOM   1539 H HH12 . ARG A 1 100 ? -33.40568 -9.66484  -12.87516 1.000 78.87043  ? 100 ARG A HH12 1 
ATOM   1540 H HH21 . ARG A 1 100 ? -32.72241 -7.45690  -10.53311 1.000 67.97662  ? 100 ARG A HH21 1 
ATOM   1541 H HH22 . ARG A 1 100 ? -32.28472 -7.95970  -11.86518 1.000 67.97662  ? 100 ARG A HH22 1 
ATOM   1542 N N    . MET A 1 101 ? -35.61197 -13.33151 -6.12915  1.000 39.60803  ? 101 MET A N    1 
ATOM   1543 C CA   . MET A 1 101 ? -36.66792 -13.92382 -5.32232  1.000 33.13187  ? 101 MET A CA   1 
ATOM   1544 C C    . MET A 1 101 ? -37.97752 -13.17326 -5.52029  1.000 52.80610  ? 101 MET A C    1 
ATOM   1545 O O    . MET A 1 101 ? -37.99839 -11.94357 -5.64164  1.000 32.41866  ? 101 MET A O    1 
ATOM   1546 C CB   . MET A 1 101 ? -36.28870 -13.92346 -3.84111  1.000 31.81270  ? 101 MET A CB   1 
ATOM   1547 C CG   . MET A 1 101 ? -35.11060 -14.82332 -3.48852  1.000 41.35622  ? 101 MET A CG   1 
ATOM   1548 S SD   . MET A 1 101 ? -35.08751 -16.39910 -4.36954  1.000 44.04763  ? 101 MET A SD   1 
ATOM   1549 C CE   . MET A 1 101 ? -36.44533 -17.26329 -3.58265  1.000 38.50588  ? 101 MET A CE   1 
ATOM   1550 H H    . MET A 1 101 ? -35.04952 -12.85882 -5.68216  1.000 47.68818  ? 101 MET A H    1 
ATOM   1551 H HA   . MET A 1 101 ? -36.78537 -14.84698 -5.59598  1.000 39.91678  ? 101 MET A HA   1 
ATOM   1552 H HB2  . MET A 1 101 ? -36.05332 -13.01855 -3.58300  1.000 38.33378  ? 101 MET A HB2  1 
ATOM   1553 H HB3  . MET A 1 101 ? -37.05303 -14.22699 -3.32675  1.000 38.33378  ? 101 MET A HB3  1 
ATOM   1554 H HG2  . MET A 1 101 ? -34.28831 -14.35554 -3.70286  1.000 49.78601  ? 101 MET A HG2  1 
ATOM   1555 H HG3  . MET A 1 101 ? -35.14325 -15.01879 -2.53899  1.000 49.78601  ? 101 MET A HG3  1 
ATOM   1556 H HE1  . MET A 1 101 ? -36.55195 -18.13173 -4.00138  1.000 46.36560  ? 101 MET A HE1  1 
ATOM   1557 H HE2  . MET A 1 101 ? -36.24578 -17.37295 -2.63976  1.000 46.36560  ? 101 MET A HE2  1 
ATOM   1558 H HE3  . MET A 1 101 ? -37.25629 -16.74217 -3.69070  1.000 46.36560  ? 101 MET A HE3  1 
ATOM   1559 N N    . GLY A 1 102 ? -39.07406 -13.92773 -5.53933  1.000 34.97613  ? 102 GLY A N    1 
ATOM   1560 C CA   . GLY A 1 102 ? -40.38013 -13.36695 -5.80599  1.000 25.72126  ? 102 GLY A CA   1 
ATOM   1561 C C    . GLY A 1 102 ? -41.32685 -13.40670 -4.62605  1.000 33.95834  ? 102 GLY A C    1 
ATOM   1562 O O    . GLY A 1 102 ? -40.92430 -13.16320 -3.48446  1.000 38.17131  ? 102 GLY A O    1 
ATOM   1563 H H    . GLY A 1 102 ? -39.08106 -14.77608 -5.39843  1.000 42.12989  ? 102 GLY A H    1 
ATOM   1564 H HA2  . GLY A 1 102 ? -40.27494 -12.44016 -6.07227  1.000 31.02406  ? 102 GLY A HA2  1 
ATOM   1565 H HA3  . GLY A 1 102 ? -40.79037 -13.85999 -6.53366  1.000 31.02406  ? 102 GLY A HA3  1 
ATOM   1566 N N    . THR A 1 103 ? -42.59067 -13.72018 -4.89348  1.000 35.20330  ? 103 THR A N    1 
ATOM   1567 C CA   . THR A 1 103 ? -43.62466 -13.62682 -3.87755  1.000 37.60927  ? 103 THR A CA   1 
ATOM   1568 C C    . THR A 1 103 ? -43.55960 -14.80899 -2.91788  1.000 33.76027  ? 103 THR A C    1 
ATOM   1569 O O    . THR A 1 103 ? -43.17206 -15.92169 -3.28778  1.000 31.95787  ? 103 THR A O    1 
ATOM   1570 C CB   . THR A 1 103 ? -45.01080 -13.57005 -4.52336  1.000 50.24993  ? 103 THR A CB   1 
ATOM   1571 O OG1  . THR A 1 103 ? -45.30591 -14.82814 -5.14181  1.000 52.79302  ? 103 THR A OG1  1 
ATOM   1572 C CG2  . THR A 1 103 ? -45.07197 -12.47453 -5.57797  1.000 55.26395  ? 103 THR A CG2  1 
ATOM   1573 H H    . THR A 1 103 ? -42.87332 -13.99037 -5.65945  1.000 42.40250  ? 103 THR A H    1 
ATOM   1574 H HA   . THR A 1 103 ? -43.48950 -12.81373 -3.36616  1.000 45.28966  ? 103 THR A HA   1 
ATOM   1575 H HB   . THR A 1 103 ? -45.67179 -13.37664 -3.84030  1.000 60.45845  ? 103 THR A HB   1 
ATOM   1576 H HG1  . THR A 1 103 ? -46.08566 -14.81887 -5.45407  1.000 63.51017  ? 103 THR A HG1  1 
ATOM   1577 H HG21 . THR A 1 103 ? -45.96567 -12.42318 -5.95155  1.000 66.47528  ? 103 THR A HG21 1 
ATOM   1578 H HG22 . THR A 1 103 ? -44.84721 -11.61864 -5.18067  1.000 66.47528  ? 103 THR A HG22 1 
ATOM   1579 H HG23 . THR A 1 103 ? -44.44304 -12.66530 -6.29138  1.000 66.47528  ? 103 THR A HG23 1 
ATOM   1580 N N    . HIS A 1 104 ? -43.93302 -14.54695 -1.66752  1.000 43.33543  ? 104 HIS A N    1 
ATOM   1581 C CA   . HIS A 1 104 ? -44.08888 -15.58615 -0.66052  1.000 30.69502  ? 104 HIS A CA   1 
ATOM   1582 C C    . HIS A 1 104 ? -45.50800 -16.13703 -0.74444  1.000 42.39908  ? 104 HIS A C    1 
ATOM   1583 O O    . HIS A 1 104 ? -46.46874 -15.37106 -0.86322  1.000 26.04973  ? 104 HIS A O    1 
ATOM   1584 C CB   . HIS A 1 104 ? -43.84137 -15.03607 0.74632   1.000 36.45321  ? 104 HIS A CB   1 
ATOM   1585 C CG   . HIS A 1 104 ? -42.49624 -14.40284 0.94163   1.000 44.15720  ? 104 HIS A CG   1 
ATOM   1586 N ND1  . HIS A 1 104 ? -41.78354 -14.53546 2.11422   1.000 50.97752  ? 104 HIS A ND1  1 
ATOM   1587 C CD2  . HIS A 1 104 ? -41.74939 -13.60970 0.13682   1.000 61.40751  ? 104 HIS A CD2  1 
ATOM   1588 C CE1  . HIS A 1 104 ? -40.64854 -13.86675 2.01712   1.000 52.92816  ? 104 HIS A CE1  1 
ATOM   1589 N NE2  . HIS A 1 104 ? -40.60235 -13.29686 0.82655   1.000 49.70614  ? 104 HIS A NE2  1 
ATOM   1590 H H    . HIS A 1 104 ? -44.10506 -13.75710 -1.37402  1.000 52.16106  ? 104 HIS A H    1 
ATOM   1591 H HA   . HIS A 1 104 ? -43.44630 -16.29562 -0.81751  1.000 36.99256  ? 104 HIS A HA   1 
ATOM   1592 H HB2  . HIS A 1 104 ? -44.51231 -14.36184 0.93646   1.000 43.90240  ? 104 HIS A HB2  1 
ATOM   1593 H HB3  . HIS A 1 104 ? -43.91569 -15.76619 1.38060   1.000 43.90240  ? 104 HIS A HB3  1 
ATOM   1594 H HD2  . HIS A 1 104 ? -41.97115 -13.32928 -0.72172  1.000 73.84756  ? 104 HIS A HD2  1 
ATOM   1595 H HE1  . HIS A 1 104 ? -39.99372 -13.80737 2.67484   1.000 63.67234  ? 104 HIS A HE1  1 
ATOM   1596 H HE2  . HIS A 1 104 ? -39.95881 -12.80904 0.53076   1.000 59.80591  ? 104 HIS A HE2  1 
ATOM   1597 N N    . ALA A 1 105 ? -45.64672 -17.45935 -0.66975  1.000 32.59396  ? 105 ALA A N    1 
ATOM   1598 C CA   . ALA A 1 105 ? -46.98542 -18.02621 -0.76490  1.000 23.88908  ? 105 ALA A CA   1 
ATOM   1599 C C    . ALA A 1 105 ? -47.00035 -19.49155 -0.36061  1.000 37.05006  ? 105 ALA A C    1 
ATOM   1600 O O    . ALA A 1 105 ? -45.97867 -20.18323 -0.39713  1.000 33.82870  ? 105 ALA A O    1 
ATOM   1601 C CB   . ALA A 1 105 ? -47.54503 -17.88056 -2.18883  1.000 41.88125  ? 105 ALA A CB   1 
ATOM   1602 H H    . ALA A 1 105 ? -45.00611 -18.02408 -0.56829  1.000 39.27129  ? 105 ALA A H    1 
ATOM   1603 H HA   . ALA A 1 105 ? -47.54616 -17.55541 -0.12864  1.000 27.87420  ? 105 ALA A HA   1 
ATOM   1604 H HB1  . ALA A 1 105 ? -48.42799 -18.28066 -2.22359  1.000 50.41604  ? 105 ALA A HB1  1 
ATOM   1605 H HB2  . ALA A 1 105 ? -47.59993 -16.93811 -2.41171  1.000 50.41604  ? 105 ALA A HB2  1 
ATOM   1606 H HB3  . ALA A 1 105 ? -46.95216 -18.33313 -2.80897  1.000 50.41604  ? 105 ALA A HB3  1 
ATOM   1607 N N    . THR A 1 106 ? -48.19168 -19.94274 0.03766   1.000 36.06118  ? 106 THR A N    1 
ATOM   1608 C CA   . THR A 1 106 ? -48.52613 -21.36101 0.12102   1.000 38.16183  ? 106 THR A CA   1 
ATOM   1609 C C    . THR A 1 106 ? -48.81697 -21.85779 -1.29128  1.000 33.80028  ? 106 THR A C    1 
ATOM   1610 O O    . THR A 1 106 ? -49.82953 -21.48024 -1.89016  1.000 48.42183  ? 106 THR A O    1 
ATOM   1611 C CB   . THR A 1 106 ? -49.73976 -21.57229 1.02301   1.000 40.48808  ? 106 THR A CB   1 
ATOM   1612 O OG1  . THR A 1 106 ? -49.46907 -21.05759 2.33175   1.000 38.28245  ? 106 THR A OG1  1 
ATOM   1613 C CG2  . THR A 1 106 ? -50.09179 -23.04771 1.12931   1.000 47.65206  ? 106 THR A CG2  1 
ATOM   1614 H H    . THR A 1 106 ? -48.84116 -19.42981 0.27151   1.000 43.43195  ? 106 THR A H    1 
ATOM   1615 H HA   . THR A 1 106 ? -47.77880 -21.85433 0.49388   1.000 45.95273  ? 106 THR A HA   1 
ATOM   1616 H HB   . THR A 1 106 ? -50.49967 -21.10585 0.64109   1.000 48.74424  ? 106 THR A HB   1 
ATOM   1617 H HG1  . THR A 1 106 ? -50.15486 -21.12048 2.81272   1.000 46.09748  ? 106 THR A HG1  1 
ATOM   1618 H HG21 . THR A 1 106 ? -50.83787 -23.16780 1.73745   1.000 57.34101  ? 106 THR A HG21 1 
ATOM   1619 H HG22 . THR A 1 106 ? -50.33772 -23.39378 0.25715   1.000 57.34101  ? 106 THR A HG22 1 
ATOM   1620 H HG23 . THR A 1 106 ? -49.33019 -23.54730 1.46289   1.000 57.34101  ? 106 THR A HG23 1 
ATOM   1621 N N    . MET A 1 107 ? -47.94094 -22.70087 -1.82658  1.000 38.60907  ? 107 MET A N    1 
ATOM   1622 C CA   . MET A 1 107 ? -48.06815 -23.20872 -3.18410  1.000 33.96224  ? 107 MET A CA   1 
ATOM   1623 C C    . MET A 1 107 ? -48.40414 -24.69464 -3.17219  1.000 42.09877  ? 107 MET A C    1 
ATOM   1624 O O    . MET A 1 107 ? -48.06391 -25.41762 -2.23194  1.000 41.71055  ? 107 MET A O    1 
ATOM   1625 C CB   . MET A 1 107 ? -46.77050 -22.98034 -3.96654  1.000 27.64473  ? 107 MET A CB   1 
ATOM   1626 C CG   . MET A 1 107 ? -46.36691 -21.52004 -4.07686  1.000 42.58333  ? 107 MET A CG   1 
ATOM   1627 S SD   . MET A 1 107 ? -44.65767 -21.28438 -4.59992  1.000 47.29526  ? 107 MET A SD   1 
ATOM   1628 C CE   . MET A 1 107 ? -43.78938 -21.77382 -3.11461  1.000 36.14027  ? 107 MET A CE   1 
ATOM   1629 H H    . MET A 1 107 ? -47.24903 -22.99896 -1.41185  1.000 46.48942  ? 107 MET A H    1 
ATOM   1630 H HA   . MET A 1 107 ? -48.78612 -22.73575 -3.63324  1.000 40.91323  ? 107 MET A HA   1 
ATOM   1631 H HB2  . MET A 1 107 ? -46.05063 -23.45294 -3.52007  1.000 33.33222  ? 107 MET A HB2  1 
ATOM   1632 H HB3  . MET A 1 107 ? -46.88508 -23.32402 -4.86635  1.000 33.33222  ? 107 MET A HB3  1 
ATOM   1633 H HG2  . MET A 1 107 ? -46.93930 -21.08520 -4.72815  1.000 51.25853  ? 107 MET A HG2  1 
ATOM   1634 H HG3  . MET A 1 107 ? -46.47248 -21.09947 -3.20917  1.000 51.25853  ? 107 MET A HG3  1 
ATOM   1635 H HE1  . MET A 1 107 ? -42.85589 -21.52360 -3.19754  1.000 43.52686  ? 107 MET A HE1  1 
ATOM   1636 H HE2  . MET A 1 107 ? -44.18648 -21.32239 -2.35341  1.000 43.52686  ? 107 MET A HE2  1 
ATOM   1637 H HE3  . MET A 1 107 ? -43.86590 -22.73470 -3.00619  1.000 43.52686  ? 107 MET A HE3  1 
ATOM   1638 N N    . LYS A 1 108 ? -49.07961 -25.14557 -4.22936  1.000 40.60477  ? 108 LYS A N    1 
ATOM   1639 C CA   . LYS A 1 108 ? -49.33942 -26.56390 -4.44701  1.000 46.18587  ? 108 LYS A CA   1 
ATOM   1640 C C    . LYS A 1 108 ? -48.30202 -27.09744 -5.43021  1.000 37.58357  ? 108 LYS A C    1 
ATOM   1641 O O    . LYS A 1 108 ? -48.18773 -26.59363 -6.55322  1.000 34.33347  ? 108 LYS A O    1 
ATOM   1642 C CB   . LYS A 1 108 ? -50.74627 -26.81122 -4.99192  1.000 28.90018  ? 108 LYS A CB   1 
ATOM   1643 C CG   . LYS A 1 108 ? -51.80899 -25.83457 -4.52219  1.000 52.36484  ? 108 LYS A CG   1 
ATOM   1644 C CD   . LYS A 1 108 ? -52.17313 -26.00032 -3.05584  1.000 54.43409  ? 108 LYS A CD   1 
ATOM   1645 C CE   . LYS A 1 108 ? -53.08150 -24.85897 -2.59581  1.000 81.35653  ? 108 LYS A CE   1 
ATOM   1646 N NZ   . LYS A 1 108 ? -52.33946 -23.75937 -1.91139  1.000 49.93993  ? 108 LYS A NZ   1 
ATOM   1647 H H    . LYS A 1 108 ? -49.40224 -24.63793 -4.84403  1.000 48.88427  ? 108 LYS A H    1 
ATOM   1648 H HA   . LYS A 1 108 ? -49.26168 -27.03083 -3.60035  1.000 55.58158  ? 108 LYS A HA   1 
ATOM   1649 H HB2  . LYS A 1 108 ? -50.71240 -26.75773 -5.95985  1.000 34.83875  ? 108 LYS A HB2  1 
ATOM   1650 H HB3  . LYS A 1 108 ? -51.02794 -27.69819 -4.71833  1.000 34.83875  ? 108 LYS A HB3  1 
ATOM   1651 H HG2  . LYS A 1 108 ? -51.48152 -24.93002 -4.64655  1.000 62.99635  ? 108 LYS A HG2  1 
ATOM   1652 H HG3  . LYS A 1 108 ? -52.61430 -25.97073 -5.04548  1.000 62.99635  ? 108 LYS A HG3  1 
ATOM   1653 H HD2  . LYS A 1 108 ? -52.64380 -26.83920 -2.93076  1.000 65.47945  ? 108 LYS A HD2  1 
ATOM   1654 H HD3  . LYS A 1 108 ? -51.36634 -25.98909 -2.51744  1.000 65.47945  ? 108 LYS A HD3  1 
ATOM   1655 H HE2  . LYS A 1 108 ? -53.52845 -24.48084 -3.36921  1.000 97.78638  ? 108 LYS A HE2  1 
ATOM   1656 H HE3  . LYS A 1 108 ? -53.73678 -25.20962 -1.97247  1.000 97.78638  ? 108 LYS A HE3  1 
ATOM   1657 H HZ1  . LYS A 1 108 ? -52.90025 -23.10372 -1.69290  1.000 60.08646  ? 108 LYS A HZ1  1 
ATOM   1658 H HZ2  . LYS A 1 108 ? -51.95305 -24.06758 -1.17126  1.000 60.08646  ? 108 LYS A HZ2  1 
ATOM   1659 H HZ3  . LYS A 1 108 ? -51.71114 -23.43411 -2.45131  1.000 60.08646  ? 108 LYS A HZ3  1 
ATOM   1660 N N    . ILE A 1 109 ? -47.55540 -28.11295 -5.01232  1.000 34.12981  ? 109 ILE A N    1 
ATOM   1661 C CA   . ILE A 1 109 ? -46.52457 -28.73064 -5.83835  1.000 37.72065  ? 109 ILE A CA   1 
ATOM   1662 C C    . ILE A 1 109 ? -46.78974 -30.22931 -5.85123  1.000 50.54969  ? 109 ILE A C    1 
ATOM   1663 O O    . ILE A 1 109 ? -46.79905 -30.87191 -4.79382  1.000 37.78032  ? 109 ILE A O    1 
ATOM   1664 C CB   . ILE A 1 109 ? -45.11275 -28.40617 -5.32112  1.000 27.94021  ? 109 ILE A CB   1 
ATOM   1665 C CG1  . ILE A 1 109 ? -44.82111 -26.91167 -5.52336  1.000 35.49356  ? 109 ILE A CG1  1 
ATOM   1666 C CG2  . ILE A 1 109 ? -44.06406 -29.24200 -6.03113  1.000 26.89466  ? 109 ILE A CG2  1 
ATOM   1667 C CD1  . ILE A 1 109 ? -43.73891 -26.35190 -4.61813  1.000 37.41048  ? 109 ILE A CD1  1 
ATOM   1668 H H    . ILE A 1 109 ? -47.62933 -28.47077 -4.23380  1.000 41.11431  ? 109 ILE A H    1 
ATOM   1669 H HA   . ILE A 1 109 ? -46.58520 -28.40963 -6.75168  1.000 45.42332  ? 109 ILE A HA   1 
ATOM   1670 H HB   . ILE A 1 109 ? -45.07858 -28.61946 -4.37548  1.000 33.68679  ? 109 ILE A HB   1 
ATOM   1671 H HG12 . ILE A 1 109 ? -44.53580 -26.77407 -6.44018  1.000 42.75081  ? 109 ILE A HG12 1 
ATOM   1672 H HG13 . ILE A 1 109 ? -45.63447 -26.41221 -5.35050  1.000 42.75081  ? 109 ILE A HG13 1 
ATOM   1673 H HG21 . ILE A 1 109 ? -43.18814 -28.86243 -5.85912  1.000 32.43213  ? 109 ILE A HG21 1 
ATOM   1674 H HG22 . ILE A 1 109 ? -44.10289 -30.15061 -5.69376  1.000 32.43213  ? 109 ILE A HG22 1 
ATOM   1675 H HG23 . ILE A 1 109 ? -44.24640 -29.23482 -6.98381  1.000 32.43213  ? 109 ILE A HG23 1 
ATOM   1676 H HD11 . ILE A 1 109 ? -44.02150 -26.44264 -3.69465  1.000 45.05111  ? 109 ILE A HD11 1 
ATOM   1677 H HD12 . ILE A 1 109 ? -42.91807 -26.84798 -4.76314  1.000 45.05111  ? 109 ILE A HD12 1 
ATOM   1678 H HD13 . ILE A 1 109 ? -43.60169 -25.41568 -4.83159  1.000 45.05111  ? 109 ILE A HD13 1 
ATOM   1679 N N    . GLN A 1 110 ? -47.03774 -30.77325 -7.04025  1.000 35.30848  ? 110 GLN A N    1 
ATOM   1680 C CA   . GLN A 1 110 ? -47.37676 -32.18306 -7.21883  1.000 35.02795  ? 110 GLN A CA   1 
ATOM   1681 C C    . GLN A 1 110 ? -48.38537 -32.63573 -6.16648  1.000 36.01288  ? 110 GLN A C    1 
ATOM   1682 O O    . GLN A 1 110 ? -48.21572 -33.65272 -5.49039  1.000 45.50292  ? 110 GLN A O    1 
ATOM   1683 C CB   . GLN A 1 110 ? -46.11989 -33.04974 -7.19120  1.000 40.28533  ? 110 GLN A CB   1 
ATOM   1684 C CG   . GLN A 1 110 ? -45.02168 -32.54980 -8.11594  1.000 47.40024  ? 110 GLN A CG   1 
ATOM   1685 C CD   . GLN A 1 110 ? -44.45898 -33.63976 -9.00194  1.000 50.46618  ? 110 GLN A CD   1 
ATOM   1686 O OE1  . GLN A 1 110 ? -43.44857 -34.26346 -8.67679  1.000 65.70084  ? 110 GLN A OE1  1 
ATOM   1687 N NE2  . GLN A 1 110 ? -45.10870 -33.87081 -10.13547 1.000 69.14075  ? 110 GLN A NE2  1 
ATOM   1688 H H    . GLN A 1 110 ? -47.01526 -30.33397 -7.77925  1.000 42.52872  ? 110 GLN A H    1 
ATOM   1689 H HA   . GLN A 1 110 ? -47.79397 -32.29202 -8.08771  1.000 42.19208  ? 110 GLN A HA   1 
ATOM   1690 H HB2  . GLN A 1 110 ? -45.76655 -33.06037 -6.28790  1.000 48.50094  ? 110 GLN A HB2  1 
ATOM   1691 H HB3  . GLN A 1 110 ? -46.35402 -33.94991 -7.46647  1.000 48.50094  ? 110 GLN A HB3  1 
ATOM   1692 H HG2  . GLN A 1 110 ? -45.38280 -31.85494 -8.68836  1.000 57.03883  ? 110 GLN A HG2  1 
ATOM   1693 H HG3  . GLN A 1 110 ? -44.29533 -32.19422 -7.58034  1.000 57.03883  ? 110 GLN A HG3  1 
ATOM   1694 H HE21 . GLN A 1 110 ? -45.80881 -33.41130 -10.33116 1.000 83.12744  ? 110 GLN A HE21 1 
ATOM   1695 H HE22 . GLN A 1 110 ? -44.82973 -34.48010 -10.67449 1.000 83.12744  ? 110 GLN A HE22 1 
ATOM   1696 N N    . GLY A 1 111 ? -49.45193 -31.84730 -6.02818  1.000 46.36089  ? 111 GLY A N    1 
ATOM   1697 C CA   . GLY A 1 111 ? -50.54558 -32.16878 -5.13940  1.000 27.95298  ? 111 GLY A CA   1 
ATOM   1698 C C    . GLY A 1 111 ? -50.33966 -31.81611 -3.68259  1.000 45.43007  ? 111 GLY A C    1 
ATOM   1699 O O    . GLY A 1 111 ? -51.31408 -31.83325 -2.91827  1.000 44.98356  ? 111 GLY A O    1 
ATOM   1700 H H    . GLY A 1 111 ? -49.55949 -31.10643 -6.45143  1.000 55.79161  ? 111 GLY A H    1 
ATOM   1701 H HA2  . GLY A 1 111 ? -51.33664 -31.69736 -5.44418  1.000 32.75087  ? 111 GLY A HA2  1 
ATOM   1702 H HA3  . GLY A 1 111 ? -50.70886 -33.12372 -5.18761  1.000 32.75087  ? 111 GLY A HA3  1 
ATOM   1703 N N    . ARG A 1 112 ? -49.11821 -31.50250 -3.26314  1.000 43.90384  ? 112 ARG A N    1 
ATOM   1704 C CA   . ARG A 1 112 ? -48.83193 -31.20930 -1.86643  1.000 31.61552  ? 112 ARG A CA   1 
ATOM   1705 C C    . ARG A 1 112 ? -48.74512 -29.70491 -1.64221  1.000 43.45812  ? 112 ARG A C    1 
ATOM   1706 O O    . ARG A 1 112 ? -48.44968 -28.93540 -2.55903  1.000 42.78501  ? 112 ARG A O    1 
ATOM   1707 C CB   . ARG A 1 112 ? -47.52900 -31.88076 -1.42587  1.000 36.53510  ? 112 ARG A CB   1 
ATOM   1708 C CG   . ARG A 1 112 ? -47.66529 -32.70720 -0.15737  1.000 55.41012  ? 112 ARG A CG   1 
ATOM   1709 C CD   . ARG A 1 112 ? -46.43474 -33.56300 0.11152   1.000 57.82163  ? 112 ARG A CD   1 
ATOM   1710 N NE   . ARG A 1 112 ? -46.48986 -34.82846 -0.61109  1.000 55.21551  ? 112 ARG A NE   1 
ATOM   1711 C CZ   . ARG A 1 112 ? -45.93493 -35.95942 -0.19461  1.000 65.70426  ? 112 ARG A CZ   1 
ATOM   1712 N NH1  . ARG A 1 112 ? -45.27276 -36.02658 0.94922   1.000 69.28458  ? 112 ARG A NH1  1 
ATOM   1713 N NH2  . ARG A 1 112 ? -46.05729 -37.05411 -0.93988  1.000 67.18096  ? 112 ARG A NH2  1 
ATOM   1714 H H    . ARG A 1 112 ? -48.43052 -31.45285 -3.77715  1.000 52.84315  ? 112 ARG A H    1 
ATOM   1715 H HA   . ARG A 1 112 ? -49.55098 -31.55258 -1.31324  1.000 38.09716  ? 112 ARG A HA   1 
ATOM   1716 H HB2  . ARG A 1 112 ? -47.22788 -32.47180 -2.13361  1.000 44.00066  ? 112 ARG A HB2  1 
ATOM   1717 H HB3  . ARG A 1 112 ? -46.86404 -31.19384 -1.26191  1.000 44.00066  ? 112 ARG A HB3  1 
ATOM   1718 H HG2  . ARG A 1 112 ? -47.78910 -32.11180 0.59832   1.000 66.65068  ? 112 ARG A HG2  1 
ATOM   1719 H HG3  . ARG A 1 112 ? -48.43000 -33.29776 -0.24320  1.000 66.65068  ? 112 ARG A HG3  1 
ATOM   1720 H HD2  . ARG A 1 112 ? -45.64196 -33.08320 -0.17520  1.000 69.54449  ? 112 ARG A HD2  1 
ATOM   1721 H HD3  . ARG A 1 112 ? -46.38030 -33.75661 1.06044   1.000 69.54449  ? 112 ARG A HD3  1 
ATOM   1722 H HE   . ARG A 1 112 ? -46.91196 -34.84272 -1.36024  1.000 66.41715  ? 112 ARG A HE   1 
ATOM   1723 H HH11 . ARG A 1 112 ? -45.19411 -35.32638 1.44230   1.000 83.30004  ? 112 ARG A HH11 1 
ATOM   1724 H HH12 . ARG A 1 112 ? -44.92109 -36.77043 1.19945   1.000 83.30004  ? 112 ARG A HH12 1 
ATOM   1725 H HH21 . ARG A 1 112 ? -46.49178 -37.02312 -1.68141  1.000 80.77569  ? 112 ARG A HH21 1 
ATOM   1726 H HH22 . ARG A 1 112 ? -45.70192 -37.79298 -0.68029  1.000 80.77569  ? 112 ARG A HH22 1 
ATOM   1727 N N    . THR A 1 113 ? -49.00624 -29.29510 -0.40424  1.000 51.41683  ? 113 THR A N    1 
ATOM   1728 C CA   . THR A 1 113 ? -49.00349 -27.88706 -0.03337  1.000 52.89077  ? 113 THR A CA   1 
ATOM   1729 C C    . THR A 1 113 ? -47.64109 -27.49054 0.52200   1.000 47.69695  ? 113 THR A C    1 
ATOM   1730 O O    . THR A 1 113 ? -47.12165 -28.14089 1.43580   1.000 33.58793  ? 113 THR A O    1 
ATOM   1731 C CB   . THR A 1 113 ? -50.09769 -27.60460 0.99624   1.000 43.79491  ? 113 THR A CB   1 
ATOM   1732 O OG1  . THR A 1 113 ? -51.37926 -27.62573 0.35473   1.000 68.89647  ? 113 THR A OG1  1 
ATOM   1733 C CG2  . THR A 1 113 ? -49.87468 -26.25356 1.64786   1.000 57.16806  ? 113 THR A CG2  1 
ATOM   1734 H H    . THR A 1 113 ? -49.19084 -29.82375 0.24848   1.000 61.85873  ? 113 THR A H    1 
ATOM   1735 H HA   . THR A 1 113 ? -49.17444 -27.34829 -0.82167  1.000 63.62747  ? 113 THR A HA   1 
ATOM   1736 H HB   . THR A 1 113 ? -50.07698 -28.28322 1.68902   1.000 52.71243  ? 113 THR A HB   1 
ATOM   1737 H HG1  . THR A 1 113 ? -51.98112 -27.43532 0.90891   1.000 82.83431  ? 113 THR A HG1  1 
ATOM   1738 H HG21 . THR A 1 113 ? -50.71071 -25.91552 2.00520   1.000 68.76021  ? 113 THR A HG21 1 
ATOM   1739 H HG22 . THR A 1 113 ? -49.23358 -26.33584 2.37113   1.000 68.76021  ? 113 THR A HG22 1 
ATOM   1740 H HG23 . THR A 1 113 ? -49.53339 -25.62260 0.99494   1.000 68.76021  ? 113 THR A HG23 1 
ATOM   1741 N N    . VAL A 1 114 ? -47.08037 -26.40667 -0.01390  1.000 40.14798  ? 114 VAL A N    1 
ATOM   1742 C CA   . VAL A 1 114 ? -45.71300 -25.99508 0.28297   1.000 37.62197  ? 114 VAL A CA   1 
ATOM   1743 C C    . VAL A 1 114 ? -45.68905 -24.50639 0.58937   1.000 28.56740  ? 114 VAL A C    1 
ATOM   1744 O O    . VAL A 1 114 ? -46.10125 -23.69057 -0.24676  1.000 36.98863  ? 114 VAL A O    1 
ATOM   1745 C CB   . VAL A 1 114 ? -44.75879 -26.29962 -0.88176  1.000 46.11983  ? 114 VAL A CB   1 
ATOM   1746 C CG1  . VAL A 1 114 ? -43.34632 -25.85553 -0.54151  1.000 38.83118  ? 114 VAL A CG1  1 
ATOM   1747 C CG2  . VAL A 1 114 ? -44.78939 -27.76915 -1.24011  1.000 37.28681  ? 114 VAL A CG2  1 
ATOM   1748 H H    . VAL A 1 114 ? -47.48342 -25.88339 -0.56465  1.000 48.33612  ? 114 VAL A H    1 
ATOM   1749 H HA   . VAL A 1 114 ? -45.41926 -26.46869 1.07689   1.000 45.30491  ? 114 VAL A HA   1 
ATOM   1750 H HB   . VAL A 1 114 ? -45.05360 -25.80211 -1.66052  1.000 55.50234  ? 114 VAL A HB   1 
ATOM   1751 H HG11 . VAL A 1 114 ? -42.72997 -26.24568 -1.18088  1.000 46.75595  ? 114 VAL A HG11 1 
ATOM   1752 H HG12 . VAL A 1 114 ? -43.30026 -24.88764 -0.58590  1.000 46.75595  ? 114 VAL A HG12 1 
ATOM   1753 H HG13 . VAL A 1 114 ? -43.12789 -26.15633 0.35443   1.000 46.75595  ? 114 VAL A HG13 1 
ATOM   1754 H HG21 . VAL A 1 114 ? -44.11997 -27.94232 -1.92040  1.000 44.90271  ? 114 VAL A HG21 1 
ATOM   1755 H HG22 . VAL A 1 114 ? -44.59695 -28.29192 -0.44603  1.000 44.90271  ? 114 VAL A HG22 1 
ATOM   1756 H HG23 . VAL A 1 114 ? -45.67042 -27.99345 -1.57832  1.000 44.90271  ? 114 VAL A HG23 1 
ATOM   1757 N N    . GLY A 1 115 ? -45.16298 -24.14380 1.76001   1.000 33.97628  ? 115 GLY A N    1 
ATOM   1758 C CA   . GLY A 1 115 ? -44.85457 -22.75741 2.06333   1.000 31.32435  ? 115 GLY A CA   1 
ATOM   1759 C C    . GLY A 1 115 ? -43.44321 -22.41659 1.64488   1.000 36.03661  ? 115 GLY A C    1 
ATOM   1760 O O    . GLY A 1 115 ? -42.49957 -23.15862 1.93056   1.000 35.33225  ? 115 GLY A O    1 
ATOM   1761 H H    . GLY A 1 115 ? -44.97579 -24.69043 2.39700   1.000 40.93007  ? 115 GLY A H    1 
ATOM   1762 H HA2  . GLY A 1 115 ? -45.46931 -22.17438 1.59102   1.000 37.74776  ? 115 GLY A HA2  1 
ATOM   1763 H HA3  . GLY A 1 115 ? -44.94292 -22.60345 3.01695   1.000 37.74776  ? 115 GLY A HA3  1 
ATOM   1764 N N    . GLY A 1 116 ? -43.29401 -21.28017 0.95967   1.000 32.51761  ? 116 GLY A N    1 
ATOM   1765 C CA   . GLY A 1 116 ? -41.99875 -20.90463 0.44231   1.000 32.86134  ? 116 GLY A CA   1 
ATOM   1766 C C    . GLY A 1 116 ? -42.07055 -19.62819 -0.36085  1.000 25.54565  ? 116 GLY A C    1 
ATOM   1767 O O    . GLY A 1 116 ? -42.97832 -18.81366 -0.18356  1.000 35.08536  ? 116 GLY A O    1 
ATOM   1768 H H    . GLY A 1 116 ? -43.92523 -20.72199 0.78762   1.000 39.17967  ? 116 GLY A H    1 
ATOM   1769 H HA2  . GLY A 1 116 ? -41.38119 -20.77187 1.17845   1.000 39.59215  ? 116 GLY A HA2  1 
ATOM   1770 H HA3  . GLY A 1 116 ? -41.66059 -21.61095 -0.13011  1.000 39.59215  ? 116 GLY A HA3  1 
ATOM   1771 N N    . GLN A 1 117 ? -41.09610 -19.46432 -1.25276  1.000 35.03616  ? 117 GLN A N    1 
ATOM   1772 C CA   . GLN A 1 117 ? -40.96068 -18.25789 -2.05842  1.000 34.21976  ? 117 GLN A CA   1 
ATOM   1773 C C    . GLN A 1 117 ? -40.53241 -18.64440 -3.46314  1.000 37.11384  ? 117 GLN A C    1 
ATOM   1774 O O    . GLN A 1 117 ? -39.56046 -19.38498 -3.63683  1.000 18.09053  ? 117 GLN A O    1 
ATOM   1775 C CB   . GLN A 1 117 ? -39.93714 -17.30100 -1.44038  1.000 41.47090  ? 117 GLN A CB   1 
ATOM   1776 C CG   . GLN A 1 117 ? -39.80254 -15.97128 -2.15602  1.000 35.38173  ? 117 GLN A CG   1 
ATOM   1777 C CD   . GLN A 1 117 ? -38.98949 -14.97242 -1.35327  1.000 48.98601  ? 117 GLN A CD   1 
ATOM   1778 O OE1  . GLN A 1 117 ? -38.21751 -15.35041 -0.47095  1.000 40.02217  ? 117 GLN A OE1  1 
ATOM   1779 N NE2  . GLN A 1 117 ? -39.16598 -13.69000 -1.64839  1.000 26.72599  ? 117 GLN A NE2  1 
ATOM   1780 H H    . GLN A 1 117 ? -40.48855 -20.05192 -1.41158  1.000 42.20193  ? 117 GLN A H    1 
ATOM   1781 H HA   . GLN A 1 117 ? -41.81593 -17.80370 -2.11461  1.000 41.22225  ? 117 GLN A HA   1 
ATOM   1782 H HB2  . GLN A 1 117 ? -40.20158 -17.11535 -0.52577  1.000 49.92362  ? 117 GLN A HB2  1 
ATOM   1783 H HB3  . GLN A 1 117 ? -39.06706 -17.72957 -1.45367  1.000 49.92362  ? 117 GLN A HB3  1 
ATOM   1784 H HG2  . GLN A 1 117 ? -39.35736 -16.11051 -3.00651  1.000 42.61662  ? 117 GLN A HG2  1 
ATOM   1785 H HG3  . GLN A 1 117 ? -40.68535 -15.59644 -2.30111  1.000 42.61662  ? 117 GLN A HG3  1 
ATOM   1786 H HE21 . GLN A 1 117 ? -39.71863 -13.46324 -2.26706  1.000 32.22973  ? 117 GLN A HE21 1 
ATOM   1787 H HE22 . GLN A 1 117 ? -38.72764 -13.08610 -1.22088  1.000 32.22973  ? 117 GLN A HE22 1 
ATOM   1788 N N    . MET A 1 118 ? -41.26164 -18.14903 -4.45750  1.000 28.23473  ? 118 MET A N    1 
ATOM   1789 C CA   . MET A 1 118 ? -40.87435 -18.37223 -5.84001  1.000 29.24412  ? 118 MET A CA   1 
ATOM   1790 C C    . MET A 1 118 ? -39.63473 -17.55059 -6.16817  1.000 38.33412  ? 118 MET A C    1 
ATOM   1791 O O    . MET A 1 118 ? -39.38625 -16.49182 -5.58421  1.000 29.44809  ? 118 MET A O    1 
ATOM   1792 C CB   . MET A 1 118 ? -42.01523 -18.00335 -6.78805  1.000 30.93429  ? 118 MET A CB   1 
ATOM   1793 C CG   . MET A 1 118 ? -43.31308 -18.74785 -6.50813  1.000 47.07104  ? 118 MET A CG   1 
ATOM   1794 S SD   . MET A 1 118 ? -44.73045 -18.09175 -7.41107  1.000 54.70130  ? 118 MET A SD   1 
ATOM   1795 C CE   . MET A 1 118 ? -44.32713 -18.56958 -9.09058  1.000 54.52217  ? 118 MET A CE   1 
ATOM   1796 H H    . MET A 1 118 ? -41.97843 -17.68460 -4.35690  1.000 34.04021  ? 118 MET A H    1 
ATOM   1797 H HA   . MET A 1 118 ? -40.68300 -19.31369 -5.97399  1.000 35.25148  ? 118 MET A HA   1 
ATOM   1798 H HB2  . MET A 1 118 ? -42.19499 -17.05383 -6.70440  1.000 37.27969  ? 118 MET A HB2  1 
ATOM   1799 H HB3  . MET A 1 118 ? -41.74503 -18.21111 -7.69619  1.000 37.27969  ? 118 MET A HB3  1 
ATOM   1800 H HG2  . MET A 1 118 ? -43.20246 -19.67682 -6.76441  1.000 56.64379  ? 118 MET A HG2  1 
ATOM   1801 H HG3  . MET A 1 118 ? -43.51094 -18.68642 -5.56052  1.000 56.64379  ? 118 MET A HG3  1 
ATOM   1802 H HE1  . MET A 1 118 ? -45.01453 -18.23526 -9.68774  1.000 65.58515  ? 118 MET A HE1  1 
ATOM   1803 H HE2  . MET A 1 118 ? -43.46760 -18.18876 -9.32949  1.000 65.58515  ? 118 MET A HE2  1 
ATOM   1804 H HE3  . MET A 1 118 ? -44.28605 -19.53733 -9.14236  1.000 65.58515  ? 118 MET A HE3  1 
ATOM   1805 N N    . GLY A 1 119 ? -38.84325 -18.06476 -7.10576  1.000 25.36730  ? 119 GLY A N    1 
ATOM   1806 C CA   . GLY A 1 119 ? -37.67990 -17.35355 -7.58781  1.000 25.53154  ? 119 GLY A CA   1 
ATOM   1807 C C    . GLY A 1 119 ? -37.51266 -17.58504 -9.07077  1.000 22.05296  ? 119 GLY A C    1 
ATOM   1808 O O    . GLY A 1 119 ? -38.12752 -18.47937 -9.65752  1.000 33.01239  ? 119 GLY A O    1 
ATOM   1809 H H    . GLY A 1 119 ? -38.96502 -18.83060 -7.47761  1.000 30.59930  ? 119 GLY A H    1 
ATOM   1810 H HA2  . GLY A 1 119 ? -37.78298 -16.40264 -7.42641  1.000 30.79639  ? 119 GLY A HA2  1 
ATOM   1811 H HA3  . GLY A 1 119 ? -36.88582 -17.66770 -7.12775  1.000 30.79639  ? 119 GLY A HA3  1 
ATOM   1812 N N    . MET A 1 120 ? -36.67598 -16.75095 -9.68090  1.000 32.70044  ? 120 MET A N    1 
ATOM   1813 C CA   . MET A 1 120 ? -36.38080 -16.83920 -11.10317 1.000 33.69296  ? 120 MET A CA   1 
ATOM   1814 C C    . MET A 1 120 ? -34.87123 -16.88685 -11.26213 1.000 32.54026  ? 120 MET A C    1 
ATOM   1815 O O    . MET A 1 120 ? -34.17044 -15.97814 -10.80564 1.000 41.65658  ? 120 MET A O    1 
ATOM   1816 C CB   . MET A 1 120 ? -36.97038 -15.65127 -11.86781 1.000 44.69011  ? 120 MET A CB   1 
ATOM   1817 C CG   . MET A 1 120 ? -36.73954 -15.70041 -13.36931 1.000 68.60016  ? 120 MET A CG   1 
ATOM   1818 S SD   . MET A 1 120 ? -37.06563 -14.12114 -14.17603 1.000 90.10981  ? 120 MET A SD   1 
ATOM   1819 C CE   . MET A 1 120 ? -36.30087 -14.40257 -15.77102 1.000 68.44661  ? 120 MET A CE   1 
ATOM   1820 H H    . MET A 1 120 ? -36.25954 -16.11307 -9.28179  1.000 39.39906  ? 120 MET A H    1 
ATOM   1821 H HA   . MET A 1 120 ? -36.77257 -17.64727 -11.46980 1.000 40.59010  ? 120 MET A HA   1 
ATOM   1822 H HB2  . MET A 1 120 ? -37.92851 -15.63071 -11.71790 1.000 53.78667  ? 120 MET A HB2  1 
ATOM   1823 H HB3  . MET A 1 120 ? -36.56482 -14.83569 -11.53426 1.000 53.78667  ? 120 MET A HB3  1 
ATOM   1824 H HG2  . MET A 1 120 ? -35.81488 -15.93906 -13.53945 1.000 82.47873  ? 120 MET A HG2  1 
ATOM   1825 H HG3  . MET A 1 120 ? -37.33044 -16.36391 -13.75854 1.000 82.47873  ? 120 MET A HG3  1 
ATOM   1826 H HE1  . MET A 1 120 ? -36.39131 -13.60143 -16.31037 1.000 82.29447  ? 120 MET A HE1  1 
ATOM   1827 H HE2  . MET A 1 120 ? -35.36216 -14.60839 -15.63925 1.000 82.29447  ? 120 MET A HE2  1 
ATOM   1828 H HE3  . MET A 1 120 ? -36.74463 -15.14675 -16.20712 1.000 82.29447  ? 120 MET A HE3  1 
ATOM   1829 N N    . LEU A 1 121 ? -34.37242 -17.94917 -11.88518 1.000 39.69794  ? 121 LEU A N    1 
ATOM   1830 C CA   . LEU A 1 121 ? -32.94805 -18.03606 -12.17109 1.000 36.05785  ? 121 LEU A CA   1 
ATOM   1831 C C    . LEU A 1 121 ? -32.58455 -16.98765 -13.21374 1.000 33.61549  ? 121 LEU A C    1 
ATOM   1832 O O    . LEU A 1 121 ? -33.29015 -16.81881 -14.21335 1.000 46.71931  ? 121 LEU A O    1 
ATOM   1833 C CB   . LEU A 1 121 ? -32.58424 -19.43636 -12.65458 1.000 30.71283  ? 121 LEU A CB   1 
ATOM   1834 C CG   . LEU A 1 121 ? -32.71646 -20.53611 -11.59680 1.000 47.20606  ? 121 LEU A CG   1 
ATOM   1835 C CD1  . LEU A 1 121 ? -32.48506 -21.91306 -12.20829 1.000 30.05939  ? 121 LEU A CD1  1 
ATOM   1836 C CD2  . LEU A 1 121 ? -31.75425 -20.29872 -10.43484 1.000 45.08574  ? 121 LEU A CD2  1 
ATOM   1837 H H    . LEU A 1 121 ? -34.83334 -18.62537 -12.14959 1.000 47.79607  ? 121 LEU A H    1 
ATOM   1838 H HA   . LEU A 1 121 ? -32.43363 -17.86779 -11.36614 1.000 43.42796  ? 121 LEU A HA   1 
ATOM   1839 H HB2  . LEU A 1 121 ? -33.16993 -19.66833 -13.39218 1.000 37.01394  ? 121 LEU A HB2  1 
ATOM   1840 H HB3  . LEU A 1 121 ? -31.66153 -19.42786 -12.95363 1.000 37.01394  ? 121 LEU A HB3  1 
ATOM   1841 H HG   . LEU A 1 121 ? -33.62024 -20.51266 -11.24532 1.000 56.80582  ? 121 LEU A HG   1 
ATOM   1842 H HD11 . LEU A 1 121 ? -32.56262 -22.58461 -11.51265 1.000 36.22980  ? 121 LEU A HD11 1 
ATOM   1843 H HD12 . LEU A 1 121 ? -33.15189 -22.06971 -12.89510 1.000 36.22980  ? 121 LEU A HD12 1 
ATOM   1844 H HD13 . LEU A 1 121 ? -31.59686 -21.94069 -12.59718 1.000 36.22980  ? 121 LEU A HD13 1 
ATOM   1845 H HD21 . LEU A 1 121 ? -31.73203 -21.09141 -9.87623  1.000 54.26143  ? 121 LEU A HD21 1 
ATOM   1846 H HD22 . LEU A 1 121 ? -30.86940 -20.11890 -10.78925 1.000 54.26143  ? 121 LEU A HD22 1 
ATOM   1847 H HD23 . LEU A 1 121 ? -32.06441 -19.53858 -9.91823  1.000 54.26143  ? 121 LEU A HD23 1 
ATOM   1848 N N    . LEU A 1 122 ? -31.49636 -16.26919 -12.96612 1.000 36.05887  ? 122 LEU A N    1 
ATOM   1849 C CA   . LEU A 1 122 ? -31.08929 -15.17037 -13.82936 1.000 43.89473  ? 122 LEU A CA   1 
ATOM   1850 C C    . LEU A 1 122 ? -29.99540 -15.61483 -14.79407 1.000 44.39342  ? 122 LEU A C    1 
ATOM   1851 O O    . LEU A 1 122 ? -28.87803 -15.92284 -14.38194 1.000 52.96552  ? 122 LEU A O    1 
ATOM   1852 C CB   . LEU A 1 122 ? -30.60929 -13.98779 -12.98650 1.000 46.14125  ? 122 LEU A CB   1 
ATOM   1853 C CG   . LEU A 1 122 ? -31.63507 -13.37006 -12.03136 1.000 60.03763  ? 122 LEU A CG   1 
ATOM   1854 C CD1  . LEU A 1 122 ? -31.04721 -12.13776 -11.34855 1.000 58.65503  ? 122 LEU A CD1  1 
ATOM   1855 C CD2  . LEU A 1 122 ? -32.92952 -13.01907 -12.75644 1.000 40.92424  ? 122 LEU A CD2  1 
ATOM   1856 H H    . LEU A 1 122 ? -30.97182 -16.40001 -12.29729 1.000 43.42918  ? 122 LEU A H    1 
ATOM   1857 H HA   . LEU A 1 122 ? -31.84826 -14.87509 -14.35631 1.000 52.83222  ? 122 LEU A HA   1 
ATOM   1858 H HB2  . LEU A 1 122 ? -29.86109 -14.28735 -12.44673 1.000 55.52804  ? 122 LEU A HB2  1 
ATOM   1859 H HB3  . LEU A 1 122 ? -30.32237 -13.28501 -13.59038 1.000 55.52804  ? 122 LEU A HB3  1 
ATOM   1860 H HG   . LEU A 1 122 ? -31.85548 -14.02325 -11.34897 1.000 72.20370  ? 122 LEU A HG   1 
ATOM   1861 H HD11 . LEU A 1 122 ? -31.71419 -11.75650 -10.75637 1.000 70.54458  ? 122 LEU A HD11 1 
ATOM   1862 H HD12 . LEU A 1 122 ? -30.26501 -12.40186 -10.83933 1.000 70.54458  ? 122 LEU A HD12 1 
ATOM   1863 H HD13 . LEU A 1 122 ? -30.79760 -11.49015 -12.02619 1.000 70.54458  ? 122 LEU A HD13 1 
ATOM   1864 H HD21 . LEU A 1 122 ? -33.49379 -12.50030 -12.16199 1.000 49.26763  ? 122 LEU A HD21 1 
ATOM   1865 H HD22 . LEU A 1 122 ? -32.71738 -12.49992 -13.54788 1.000 49.26763  ? 122 LEU A HD22 1 
ATOM   1866 H HD23 . LEU A 1 122 ? -33.38174 -13.83889 -13.01000 1.000 49.26763  ? 122 LEU A HD23 1 
ATOM   1867 N N    . GLY A 1 133 ? -29.07690 -24.25021 -14.49989 1.000 54.93839  ? 133 GLY A N    1 
ATOM   1868 C CA   . GLY A 1 133 ? -30.30611 -24.96624 -14.21494 1.000 38.32024  ? 133 GLY A CA   1 
ATOM   1869 C C    . GLY A 1 133 ? -30.19152 -25.82645 -12.97325 1.000 47.56633  ? 133 GLY A C    1 
ATOM   1870 O O    . GLY A 1 133 ? -29.08749 -26.07816 -12.49205 1.000 47.28379  ? 133 GLY A O    1 
ATOM   1871 H H    . GLY A 1 133 ? -28.38504 -24.75775 -14.55634 1.000 66.08461  ? 133 GLY A H    1 
ATOM   1872 H HA2  . GLY A 1 133 ? -31.02581 -24.32965 -14.08192 1.000 46.14283  ? 133 GLY A HA2  1 
ATOM   1873 H HA3  . GLY A 1 133 ? -30.52614 -25.53927 -14.96602 1.000 46.14283  ? 133 GLY A HA3  1 
ATOM   1874 N N    . THR A 1 134 ? -31.33032 -26.27158 -12.44936 1.000 32.43370  ? 134 THR A N    1 
ATOM   1875 C CA   . THR A 1 134 ? -31.37701 -27.14966 -11.29085 1.000 31.67295  ? 134 THR A CA   1 
ATOM   1876 C C    . THR A 1 134 ? -31.84825 -28.53810 -11.70716 1.000 45.92305  ? 134 THR A C    1 
ATOM   1877 O O    . THR A 1 134 ? -32.48177 -28.71876 -12.75172 1.000 51.59854  ? 134 THR A O    1 
ATOM   1878 C CB   . THR A 1 134 ? -32.29657 -26.58361 -10.20320 1.000 28.53088  ? 134 THR A CB   1 
ATOM   1879 O OG1  . THR A 1 134 ? -33.62147 -26.41948 -10.72204 1.000 48.03926  ? 134 THR A OG1  1 
ATOM   1880 C CG2  . THR A 1 134 ? -31.77655 -25.24122 -9.71866  1.000 42.81973  ? 134 THR A CG2  1 
ATOM   1881 H H    . THR A 1 134 ? -32.10775 -26.07165 -12.75795 1.000 39.07898  ? 134 THR A H    1 
ATOM   1882 H HA   . THR A 1 134 ? -30.48722 -27.23124 -10.91334 1.000 38.16608  ? 134 THR A HA   1 
ATOM   1883 H HB   . THR A 1 134 ? -32.32187 -27.19616 -9.45150  1.000 34.39559  ? 134 THR A HB   1 
ATOM   1884 H HG1  . THR A 1 134 ? -34.12661 -26.10903 -10.12701 1.000 57.80565  ? 134 THR A HG1  1 
ATOM   1885 H HG21 . THR A 1 134 ? -32.23196 -24.98430 -8.90166  1.000 51.54222  ? 134 THR A HG21 1 
ATOM   1886 H HG22 . THR A 1 134 ? -30.82415 -25.29793 -9.54369  1.000 51.54222  ? 134 THR A HG22 1 
ATOM   1887 H HG23 . THR A 1 134 ? -31.93279 -24.56184 -10.39315 1.000 51.54222  ? 134 THR A HG23 1 
ATOM   1888 N N    . THR A 1 135 ? -31.51826 -29.52778 -10.87148 1.000 44.56958  ? 135 THR A N    1 
ATOM   1889 C CA   . THR A 1 135 ? -31.77541 -30.92718 -11.18972 1.000 50.56304  ? 135 THR A CA   1 
ATOM   1890 C C    . THR A 1 135 ? -32.26402 -31.67584 -9.95352  1.000 30.67232  ? 135 THR A C    1 
ATOM   1891 O O    . THR A 1 135 ? -32.23969 -31.12401 -8.84634  1.000 37.10831  ? 135 THR A O    1 
ATOM   1892 C CB   . THR A 1 135 ? -30.51220 -31.59906 -11.73370 1.000 49.06723  ? 135 THR A CB   1 
ATOM   1893 O OG1  . THR A 1 135 ? -29.65704 -31.96346 -10.64243 1.000 59.85725  ? 135 THR A OG1  1 
ATOM   1894 C CG2  . THR A 1 135 ? -29.75235 -30.66264 -12.66069 1.000 43.18693  ? 135 THR A CG2  1 
ATOM   1895 H H    . THR A 1 135 ? -31.14098 -29.40921 -10.10781 1.000 53.64203  ? 135 THR A H    1 
ATOM   1896 H HA   . THR A 1 135 ? -32.46855 -30.96806 -11.86706 1.000 60.83419  ? 135 THR A HA   1 
ATOM   1897 H HB   . THR A 1 135 ? -30.76508 -32.38897 -12.23669 1.000 59.03921  ? 135 THR A HB   1 
ATOM   1898 H HG1  . THR A 1 135 ? -28.98098 -32.37023 -10.93066 1.000 71.98724  ? 135 THR A HG1  1 
ATOM   1899 H HG21 . THR A 1 135 ? -29.06321 -31.15303 -13.13555 1.000 51.98285  ? 135 THR A HG21 1 
ATOM   1900 H HG22 . THR A 1 135 ? -30.36033 -30.26936 -13.30614 1.000 51.98285  ? 135 THR A HG22 1 
ATOM   1901 H HG23 . THR A 1 135 ? -29.33632 -29.95278 -12.14696 1.000 51.98285  ? 135 THR A HG23 1 
ATOM   1902 N N    . PRO A 1 136 ? -32.70229 -32.93178 -10.09476 1.000 44.61818  ? 136 PRO A N    1 
ATOM   1903 C CA   . PRO A 1 136 ? -33.23896 -33.65215 -8.92470  1.000 52.88306  ? 136 PRO A CA   1 
ATOM   1904 C C    . PRO A 1 136 ? -32.31180 -33.68500 -7.71914  1.000 59.67336  ? 136 PRO A C    1 
ATOM   1905 O O    . PRO A 1 136 ? -32.77178 -33.48319 -6.58847  1.000 66.32724  ? 136 PRO A O    1 
ATOM   1906 C CB   . PRO A 1 136 ? -33.48933 -35.06345 -9.48088  1.000 28.88909  ? 136 PRO A CB   1 
ATOM   1907 C CG   . PRO A 1 136 ? -33.77350 -34.83934 -10.93314 1.000 24.93846  ? 136 PRO A CG   1 
ATOM   1908 C CD   . PRO A 1 136 ? -32.87845 -33.69564 -11.34628 1.000 35.61738  ? 136 PRO A CD   1 
ATOM   1909 H HA   . PRO A 1 136 ? -34.07755 -33.24271 -8.66007  1.000 63.61822  ? 136 PRO A HA   1 
ATOM   1910 H HB2  . PRO A 1 136 ? -32.70048 -35.61467 -9.35937  1.000 34.82545  ? 136 PRO A HB2  1 
ATOM   1911 H HB3  . PRO A 1 136 ? -34.24902 -35.46827 -9.03378  1.000 34.82545  ? 136 PRO A HB3  1 
ATOM   1912 H HG2  . PRO A 1 136 ? -33.56338 -35.64122 -11.43685 1.000 29.77358  ? 136 PRO A HG2  1 
ATOM   1913 H HG3  . PRO A 1 136 ? -34.70761 -34.60724 -11.05340 1.000 29.77358  ? 136 PRO A HG3  1 
ATOM   1914 H HD2  . PRO A 1 136 ? -32.02632 -34.02479 -11.67251 1.000 42.89939  ? 136 PRO A HD2  1 
ATOM   1915 H HD3  . PRO A 1 136 ? -33.30585 -33.15103 -12.02571 1.000 42.89939  ? 136 PRO A HD3  1 
ATOM   1916 N N    . GLY A 1 137 ? -31.02195 -33.93582 -7.92159  1.000 44.29941  ? 137 GLY A N    1 
ATOM   1917 C CA   . GLY A 1 137 ? -30.10867 -34.07677 -6.80372  1.000 44.41760  ? 137 GLY A CA   1 
ATOM   1918 C C    . GLY A 1 137 ? -29.74564 -32.79403 -6.08697  1.000 41.06423  ? 137 GLY A C    1 
ATOM   1919 O O    . GLY A 1 137 ? -28.96335 -32.84256 -5.13230  1.000 44.47005  ? 137 GLY A O    1 
ATOM   1920 H H    . GLY A 1 137 ? -30.65689 -34.02762 -8.69483  1.000 53.31784  ? 137 GLY A H    1 
ATOM   1921 H HA2  . GLY A 1 137 ? -30.51061 -34.67207 -6.15182  1.000 53.45966  ? 137 GLY A HA2  1 
ATOM   1922 H HA3  . GLY A 1 137 ? -29.28505 -34.47344 -7.12804  1.000 53.45966  ? 137 GLY A HA3  1 
ATOM   1923 N N    . ASP A 1 138 ? -30.28803 -31.65365 -6.50565  1.000 29.80123  ? 138 ASP A N    1 
ATOM   1924 C CA   . ASP A 1 138 ? -29.92796 -30.36803 -5.92477  1.000 39.22817  ? 138 ASP A CA   1 
ATOM   1925 C C    . ASP A 1 138 ? -30.78410 -29.98172 -4.72714  1.000 38.33538  ? 138 ASP A C    1 
ATOM   1926 O O    . ASP A 1 138 ? -30.53279 -28.93477 -4.11971  1.000 38.18040  ? 138 ASP A O    1 
ATOM   1927 C CB   . ASP A 1 138 ? -30.03728 -29.25882 -6.97738  1.000 24.99185  ? 138 ASP A CB   1 
ATOM   1928 C CG   . ASP A 1 138 ? -29.06299 -29.43823 -8.11599  1.000 36.81640  ? 138 ASP A CG   1 
ATOM   1929 O OD1  . ASP A 1 138 ? -28.01953 -30.09331 -7.91223  1.000 36.69808  ? 138 ASP A OD1  1 
ATOM   1930 O OD2  . ASP A 1 138 ? -29.33975 -28.91331 -9.21491  1.000 39.89404  ? 138 ASP A OD2  1 
ATOM   1931 H H    . ASP A 1 138 ? -30.87404 -31.60022 -7.13281  1.000 35.92001  ? 138 ASP A H    1 
ATOM   1932 H HA   . ASP A 1 138 ? -29.00566 -30.42791 -5.63035  1.000 47.23234  ? 138 ASP A HA   1 
ATOM   1933 H HB2  . ASP A 1 138 ? -30.93421 -29.26052 -7.34671  1.000 30.14876  ? 138 ASP A HB2  1 
ATOM   1934 H HB3  . ASP A 1 138 ? -29.85332 -28.40434 -6.55674  1.000 30.14876  ? 138 ASP A HB3  1 
ATOM   1935 N N    . CYS A 1 139 ? -31.78536 -30.78221 -4.37462  1.000 28.78966  ? 139 CYS A N    1 
ATOM   1936 C CA   . CYS A 1 139 ? -32.69822 -30.38503 -3.31235  1.000 29.25592  ? 139 CYS A CA   1 
ATOM   1937 C C    . CYS A 1 139 ? -32.00315 -30.41587 -1.96048  1.000 33.27523  ? 139 CYS A C    1 
ATOM   1938 O O    . CYS A 1 139 ? -31.16525 -31.28346 -1.69129  1.000 26.58103  ? 139 CYS A O    1 
ATOM   1939 C CB   . CYS A 1 139 ? -33.92682 -31.28845 -3.28875  1.000 38.19559  ? 139 CYS A CB   1 
ATOM   1940 S SG   . CYS A 1 139 ? -35.11715 -30.93203 -4.58978  1.000 34.47470  ? 139 CYS A SG   1 
ATOM   1941 H H    . CYS A 1 139 ? -31.95404 -31.54721 -4.72948  1.000 34.70613  ? 139 CYS A H    1 
ATOM   1942 H HA   . CYS A 1 139 ? -32.99646 -29.47730 -3.47960  1.000 35.26565  ? 139 CYS A HA   1 
ATOM   1943 H HB2  . CYS A 1 139 ? -33.63877 -32.20854 -3.39531  1.000 45.99325  ? 139 CYS A HB2  1 
ATOM   1944 H HB3  . CYS A 1 139 ? -34.37777 -31.17851 -2.43701  1.000 45.99325  ? 139 CYS A HB3  1 
ATOM   1945 N N    . GLY A 1 140 ? -32.37515 -29.46893 -1.10444  1.000 27.77118  ? 140 GLY A N    1 
ATOM   1946 C CA   . GLY A 1 140 ? -31.73726 -29.27261 0.17323   1.000 26.96522  ? 140 GLY A CA   1 
ATOM   1947 C C    . GLY A 1 140 ? -30.68434 -28.18568 0.18545   1.000 31.48193  ? 140 GLY A C    1 
ATOM   1948 O O    . GLY A 1 140 ? -30.26246 -27.76944 1.27201   1.000 25.00809  ? 140 GLY A O    1 
ATOM   1949 H H    . GLY A 1 140 ? -33.01561 -28.91483 -1.25409  1.000 33.48395  ? 140 GLY A H    1 
ATOM   1950 H HA2  . GLY A 1 140 ? -32.41395 -29.03908 0.82779   1.000 32.51680  ? 140 GLY A HA2  1 
ATOM   1951 H HA3  . GLY A 1 140 ? -31.31193 -30.10226 0.44095   1.000 32.51680  ? 140 GLY A HA3  1 
ATOM   1952 N N    . CYS A 1 141 ? -30.25154 -27.70826 -0.98860  1.000 29.28171  ? 141 CYS A N    1 
ATOM   1953 C CA   . CYS A 1 141 ? -29.23341 -26.67104 -1.06300  1.000 28.34066  ? 141 CYS A CA   1 
ATOM   1954 C C    . CYS A 1 141 ? -29.81895 -25.30721 -0.69790  1.000 28.03009  ? 141 CYS A C    1 
ATOM   1955 O O    . CYS A 1 141 ? -30.98291 -25.02187 -0.99367  1.000 31.90940  ? 141 CYS A O    1 
ATOM   1956 C CB   . CYS A 1 141 ? -28.63281 -26.61365 -2.46359  1.000 26.34925  ? 141 CYS A CB   1 
ATOM   1957 S SG   . CYS A 1 141 ? -27.54749 -28.00292 -2.87326  1.000 32.24134  ? 141 CYS A SG   1 
ATOM   1958 H H    . CYS A 1 141 ? -30.53644 -27.97333 -1.75552  1.000 35.29659  ? 141 CYS A H    1 
ATOM   1959 H HA   . CYS A 1 141 ? -28.52288 -26.87278 -0.43423  1.000 34.16733  ? 141 CYS A HA   1 
ATOM   1960 H HB2  . CYS A 1 141 ? -29.35629 -26.60670 -3.10967  1.000 31.77764  ? 141 CYS A HB2  1 
ATOM   1961 H HB3  . CYS A 1 141 ? -28.10999 -25.80040 -2.54220  1.000 31.77764  ? 141 CYS A HB3  1 
ATOM   1962 H HG   . CYS A 1 141 ? -28.18833 -29.01735 -2.85696  1.000 38.84815  ? 141 CYS A HG   1 
ATOM   1963 N N    . PRO A 1 142 ? -29.02077 -24.43942 -0.07862  1.000 36.78685  ? 142 PRO A N    1 
ATOM   1964 C CA   . PRO A 1 142 ? -29.56370 -23.21515 0.51208   1.000 43.59938  ? 142 PRO A CA   1 
ATOM   1965 C C    . PRO A 1 142 ? -29.63564 -22.03918 -0.44542  1.000 40.05802  ? 142 PRO A C    1 
ATOM   1966 O O    . PRO A 1 142 ? -28.87101 -21.92233 -1.40447  1.000 30.03670  ? 142 PRO A O    1 
ATOM   1967 C CB   . PRO A 1 142 ? -28.55608 -22.91602 1.63255   1.000 32.96763  ? 142 PRO A CB   1 
ATOM   1968 C CG   . PRO A 1 142 ? -27.25513 -23.34724 1.02976   1.000 39.28167  ? 142 PRO A CG   1 
ATOM   1969 C CD   . PRO A 1 142 ? -27.56935 -24.55851 0.16253   1.000 30.87397  ? 142 PRO A CD   1 
ATOM   1970 H HA   . PRO A 1 142 ? -30.44979 -23.38520 0.86820   1.000 52.47780  ? 142 PRO A HA   1 
ATOM   1971 H HB2  . PRO A 1 142 ? -28.55375 -21.96910 1.84291   1.000 39.71970  ? 142 PRO A HB2  1 
ATOM   1972 H HB3  . PRO A 1 142 ? -28.76825 -23.43167 2.42627   1.000 39.71970  ? 142 PRO A HB3  1 
ATOM   1973 H HG2  . PRO A 1 142 ? -26.89054 -22.62680 0.49222   1.000 47.29654  ? 142 PRO A HG2  1 
ATOM   1974 H HG3  . PRO A 1 142 ? -26.63196 -23.58338 1.73460   1.000 47.29654  ? 142 PRO A HG3  1 
ATOM   1975 H HD2  . PRO A 1 142 ? -27.07694 -24.52188 -0.67239  1.000 37.20731  ? 142 PRO A HD2  1 
ATOM   1976 H HD3  . PRO A 1 142 ? -27.36434 -25.38177 0.63275   1.000 37.20731  ? 142 PRO A HD3  1 
ATOM   1977 N N    . TYR A 1 143 ? -30.58363 -21.15488 -0.15054  1.000 24.24757  ? 143 TYR A N    1 
ATOM   1978 C CA   . TYR A 1 143 ? -30.64464 -19.82272 -0.73143  1.000 33.82022  ? 143 TYR A CA   1 
ATOM   1979 C C    . TYR A 1 143 ? -30.08021 -18.83712 0.28350   1.000 32.18116  ? 143 TYR A C    1 
ATOM   1980 O O    . TYR A 1 143 ? -30.38799 -18.91913 1.47652   1.000 32.59492  ? 143 TYR A O    1 
ATOM   1981 C CB   . TYR A 1 143 ? -32.07844 -19.44122 -1.09509  1.000 36.35921  ? 143 TYR A CB   1 
ATOM   1982 C CG   . TYR A 1 143 ? -32.66263 -20.22829 -2.24921  1.000 41.79911  ? 143 TYR A CG   1 
ATOM   1983 C CD1  . TYR A 1 143 ? -32.92125 -21.58707 -2.12933  1.000 32.74437  ? 143 TYR A CD1  1 
ATOM   1984 C CD2  . TYR A 1 143 ? -32.97255 -19.60646 -3.45290  1.000 43.12596  ? 143 TYR A CD2  1 
ATOM   1985 C CE1  . TYR A 1 143 ? -33.46275 -22.30702 -3.17735  1.000 28.93264  ? 143 TYR A CE1  1 
ATOM   1986 C CE2  . TYR A 1 143 ? -33.51272 -20.31776 -4.50717  1.000 31.64018  ? 143 TYR A CE2  1 
ATOM   1987 C CZ   . TYR A 1 143 ? -33.75425 -21.66758 -4.36466  1.000 46.33694  ? 143 TYR A CZ   1 
ATOM   1988 O OH   . TYR A 1 143 ? -34.29519 -22.37839 -5.41202  1.000 36.90172  ? 143 TYR A OH   1 
ATOM   1989 H H    . TYR A 1 143 ? -31.22339 -21.31094 0.40259   1.000 29.25562  ? 143 TYR A H    1 
ATOM   1990 H HA   . TYR A 1 143 ? -30.12254 -19.78421 -1.54802  1.000 40.74280  ? 143 TYR A HA   1 
ATOM   1991 H HB2  . TYR A 1 143 ? -32.64408 -19.59165 -0.32157  1.000 43.78959  ? 143 TYR A HB2  1 
ATOM   1992 H HB3  . TYR A 1 143 ? -32.09580 -18.50318 -1.34139  1.000 43.78959  ? 143 TYR A HB3  1 
ATOM   1993 H HD1  . TYR A 1 143 ? -32.72669 -22.02037 -1.32977  1.000 39.45179  ? 143 TYR A HD1  1 
ATOM   1994 H HD2  . TYR A 1 143 ? -32.81354 -18.69537 -3.55050  1.000 51.90970  ? 143 TYR A HD2  1 
ATOM   1995 H HE1  . TYR A 1 143 ? -33.62966 -23.21703 -3.08285  1.000 34.87771  ? 143 TYR A HE1  1 
ATOM   1996 H HE2  . TYR A 1 143 ? -33.71210 -19.88867 -5.30781  1.000 38.12675  ? 143 TYR A HE2  1 
ATOM   1997 H HH   . TYR A 1 143 ? -34.68402 -23.06462 -5.12306  1.000 44.44060  ? 143 TYR A HH   1 
ATOM   1998 N N    . ILE A 1 144 ? -29.24034 -17.91912 -0.18623  1.000 43.91760  ? 144 ILE A N    1 
ATOM   1999 C CA   . ILE A 1 144 ? -28.56367 -16.97604 0.69861   1.000 44.03513  ? 144 ILE A CA   1 
ATOM   2000 C C    . ILE A 1 144 ? -28.40400 -15.64942 -0.02982  1.000 45.28768  ? 144 ILE A C    1 
ATOM   2001 O O    . ILE A 1 144 ? -28.17339 -15.61410 -1.24199  1.000 35.55479  ? 144 ILE A O    1 
ATOM   2002 C CB   . ILE A 1 144 ? -27.19236 -17.52190 1.16563   1.000 35.25306  ? 144 ILE A CB   1 
ATOM   2003 C CG1  . ILE A 1 144 ? -27.37565 -18.86846 1.87545   1.000 22.27171  ? 144 ILE A CG1  1 
ATOM   2004 C CG2  . ILE A 1 144 ? -26.48766 -16.50274 2.06254   1.000 45.19884  ? 144 ILE A CG2  1 
ATOM   2005 C CD1  . ILE A 1 144 ? -26.10891 -19.44516 2.46163   1.000 45.45601  ? 144 ILE A CD1  1 
ATOM   2006 H H    . ILE A 1 144 ? -29.04502 -17.82202 -1.01811  1.000 52.85966  ? 144 ILE A H    1 
ATOM   2007 H HA   . ILE A 1 144 ? -29.11877 -16.82765 1.48011   1.000 53.00069  ? 144 ILE A HA   1 
ATOM   2008 H HB   . ILE A 1 144 ? -26.63024 -17.66768 0.38867   1.000 42.46221  ? 144 ILE A HB   1 
ATOM   2009 H HG12 . ILE A 1 144 ? -28.00763 -18.75128 2.60193   1.000 26.88459  ? 144 ILE A HG12 1 
ATOM   2010 H HG13 . ILE A 1 144 ? -27.72101 -19.51052 1.23561   1.000 26.88459  ? 144 ILE A HG13 1 
ATOM   2011 H HG21 . ILE A 1 144 ? -25.61723 -16.85041 2.31229   1.000 54.39715  ? 144 ILE A HG21 1 
ATOM   2012 H HG22 . ILE A 1 144 ? -26.38398 -15.67092 1.57445   1.000 54.39715  ? 144 ILE A HG22 1 
ATOM   2013 H HG23 . ILE A 1 144 ? -27.02530 -16.35564 2.85639   1.000 54.39715  ? 144 ILE A HG23 1 
ATOM   2014 H HD11 . ILE A 1 144 ? -26.30820 -20.30838 2.85666   1.000 54.70576  ? 144 ILE A HD11 1 
ATOM   2015 H HD12 . ILE A 1 144 ? -25.45242 -19.54837 1.75505   1.000 54.70576  ? 144 ILE A HD12 1 
ATOM   2016 H HD13 . ILE A 1 144 ? -25.77147 -18.84051 3.14092   1.000 54.70576  ? 144 ILE A HD13 1 
ATOM   2017 N N    . TYR A 1 145 ? -28.52895 -14.55522 0.71998   1.000 43.82553  ? 145 TYR A N    1 
ATOM   2018 C CA   . TYR A 1 145 ? -28.23583 -13.22253 0.21114   1.000 43.26620  ? 145 TYR A CA   1 
ATOM   2019 C C    . TYR A 1 145 ? -27.48630 -12.44714 1.28538   1.000 47.36812  ? 145 TYR A C    1 
ATOM   2020 O O    . TYR A 1 145 ? -27.52096 -12.79462 2.46878   1.000 40.59159  ? 145 TYR A O    1 
ATOM   2021 C CB   . TYR A 1 145 ? -29.51401 -12.48327 -0.22833  1.000 27.32567  ? 145 TYR A CB   1 
ATOM   2022 C CG   . TYR A 1 145 ? -30.41556 -11.95883 0.87609   1.000 28.22653  ? 145 TYR A CG   1 
ATOM   2023 C CD1  . TYR A 1 145 ? -31.20132 -12.81602 1.63582   1.000 38.22376  ? 145 TYR A CD1  1 
ATOM   2024 C CD2  . TYR A 1 145 ? -30.51520 -10.59488 1.12288   1.000 39.94902  ? 145 TYR A CD2  1 
ATOM   2025 C CE1  . TYR A 1 145 ? -32.03886 -12.32988 2.63104   1.000 42.75449  ? 145 TYR A CE1  1 
ATOM   2026 C CE2  . TYR A 1 145 ? -31.34865 -10.10158 2.11232   1.000 50.21447  ? 145 TYR A CE2  1 
ATOM   2027 C CZ   . TYR A 1 145 ? -32.10729 -10.97163 2.86277   1.000 42.87512  ? 145 TYR A CZ   1 
ATOM   2028 O OH   . TYR A 1 145 ? -32.93442 -10.47685 3.84559   1.000 48.88999  ? 145 TYR A OH   1 
ATOM   2029 H H    . TYR A 1 145 ? -28.78655 -14.56185 1.54047   1.000 52.74918  ? 145 TYR A H    1 
ATOM   2030 H HA   . TYR A 1 145 ? -27.66056 -13.28256 -0.56755  1.000 52.07798  ? 145 TYR A HA   1 
ATOM   2031 H HB2  . TYR A 1 145 ? -29.24950 -11.71939 -0.76445  1.000 31.99810  ? 145 TYR A HB2  1 
ATOM   2032 H HB3  . TYR A 1 145 ? -30.04588 -13.09460 -0.76152  1.000 31.99810  ? 145 TYR A HB3  1 
ATOM   2033 H HD1  . TYR A 1 145 ? -31.16588 -13.73135 1.47518   1.000 46.02705  ? 145 TYR A HD1  1 
ATOM   2034 H HD2  . TYR A 1 145 ? -30.01202 -10.00160 0.61325   1.000 48.09736  ? 145 TYR A HD2  1 
ATOM   2035 H HE1  . TYR A 1 145 ? -32.55109 -12.91698 3.13881   1.000 51.46393  ? 145 TYR A HE1  1 
ATOM   2036 H HE2  . TYR A 1 145 ? -31.39586 -9.18616  2.26941   1.000 60.41590  ? 145 TYR A HE2  1 
ATOM   2037 H HH   . TYR A 1 145 ? -32.86074 -9.64123  3.88931   1.000 58.82653  ? 145 TYR A HH   1 
ATOM   2038 N N    . LYS A 1 146 ? -26.77758 -11.40673 0.85705   1.000 35.83279  ? 146 LYS A N    1 
ATOM   2039 C CA   . LYS A 1 146 ? -26.03212 -10.55560 1.77226   1.000 46.14607  ? 146 LYS A CA   1 
ATOM   2040 C C    . LYS A 1 146 ? -26.84201 -9.30562  2.08840   1.000 47.97189  ? 146 LYS A C    1 
ATOM   2041 O O    . LYS A 1 146 ? -27.35061 -8.64162  1.17873   1.000 50.95299  ? 146 LYS A O    1 
ATOM   2042 C CB   . LYS A 1 146 ? -24.67513 -10.14915 1.19748   1.000 66.17777  ? 146 LYS A CB   1 
ATOM   2043 C CG   . LYS A 1 146 ? -23.77480 -9.51151  2.24760   1.000 58.62573  ? 146 LYS A CG   1 
ATOM   2044 C CD   . LYS A 1 146 ? -22.46282 -9.00154  1.68143   1.000 78.20329  ? 146 LYS A CD   1 
ATOM   2045 C CE   . LYS A 1 146 ? -21.39575 -8.98414  2.76960   1.000 78.99348  ? 146 LYS A CE   1 
ATOM   2046 N NZ   . LYS A 1 146 ? -20.27299 -8.05464  2.47581   1.000 69.31690  ? 146 LYS A NZ   1 
ATOM   2047 H H    . LYS A 1 146 ? -26.71395 -11.17320 0.03181   1.000 43.15789  ? 146 LYS A H    1 
ATOM   2048 H HA   . LYS A 1 146 ? -25.87761 -11.05146 2.59150   1.000 55.53382  ? 146 LYS A HA   1 
ATOM   2049 H HB2  . LYS A 1 146 ? -24.22703 -10.93714 0.85226   1.000 79.57187  ? 146 LYS A HB2  1 
ATOM   2050 H HB3  . LYS A 1 146 ? -24.81155 -9.50591  0.48436   1.000 79.57187  ? 146 LYS A HB3  1 
ATOM   2051 H HG2  . LYS A 1 146 ? -24.23965 -8.75886  2.64550   1.000 70.50942  ? 146 LYS A HG2  1 
ATOM   2052 H HG3  . LYS A 1 146 ? -23.56868 -10.17145 2.92796   1.000 70.50942  ? 146 LYS A HG3  1 
ATOM   2053 H HD2  . LYS A 1 146 ? -22.16710 -9.58510  0.96526   1.000 94.00249  ? 146 LYS A HD2  1 
ATOM   2054 H HD3  . LYS A 1 146 ? -22.58027 -8.09875  1.34665   1.000 94.00249  ? 146 LYS A HD3  1 
ATOM   2055 H HE2  . LYS A 1 146 ? -21.80271 -8.70476  3.60460   1.000 94.95072  ? 146 LYS A HE2  1 
ATOM   2056 H HE3  . LYS A 1 146 ? -21.02687 -9.87644  2.86254   1.000 94.95072  ? 146 LYS A HE3  1 
ATOM   2057 H HZ1  . LYS A 1 146 ? -19.66829 -8.09206  3.12777   1.000 83.33882  ? 146 LYS A HZ1  1 
ATOM   2058 H HZ2  . LYS A 1 146 ? -19.88401 -8.28030  1.70778   1.000 83.33882  ? 146 LYS A HZ2  1 
ATOM   2059 H HZ3  . LYS A 1 146 ? -20.57711 -7.22069  2.41147   1.000 83.33882  ? 146 LYS A HZ3  1 
ATOM   2060 N N    . ARG A 1 147 ? -26.93859 -8.98222  3.37600   1.000 66.31649  ? 147 ARG A N    1 
ATOM   2061 C CA   . ARG A 1 147 ? -27.63423 -7.79198  3.86465   1.000 64.91745  ? 147 ARG A CA   1 
ATOM   2062 C C    . ARG A 1 147 ? -26.65288 -7.05856  4.77501   1.000 64.39485  ? 147 ARG A C    1 
ATOM   2063 O O    . ARG A 1 147 ? -26.46732 -7.44387  5.93338   1.000 60.54061  ? 147 ARG A O    1 
ATOM   2064 C CB   . ARG A 1 147 ? -28.91646 -8.16997  4.59776   1.000 70.50716  ? 147 ARG A CB   1 
ATOM   2065 C CG   . ARG A 1 147 ? -29.76634 -6.99328  5.06018   1.000 63.83828  ? 147 ARG A CG   1 
ATOM   2066 C CD   . ARG A 1 147 ? -31.04022 -7.48523  5.73683   1.000 61.19352  ? 147 ARG A CD   1 
ATOM   2067 N NE   . ARG A 1 147 ? -30.74222 -8.38505  6.84571   1.000 80.20165  ? 147 ARG A NE   1 
ATOM   2068 C CZ   . ARG A 1 147 ? -31.64715 -9.09467  7.50583   1.000 69.89855  ? 147 ARG A CZ   1 
ATOM   2069 N NH1  . ARG A 1 147 ? -32.93373 -9.02579  7.20552   1.000 55.74376  ? 147 ARG A NH1  1 
ATOM   2070 N NH2  . ARG A 1 147 ? -31.24992 -9.89909  8.48754   1.000 72.87516  ? 147 ARG A NH2  1 
ATOM   2071 H H    . ARG A 1 147 ? -26.59693 -9.45359  4.00900   1.000 79.73833  ? 147 ARG A H    1 
ATOM   2072 H HA   . ARG A 1 147 ? -27.87634 -7.21088  3.12667   1.000 78.05948  ? 147 ARG A HA   1 
ATOM   2073 H HB2  . ARG A 1 147 ? -29.46292 -8.70704  4.00291   1.000 84.76714  ? 147 ARG A HB2  1 
ATOM   2074 H HB3  . ARG A 1 147 ? -28.67929 -8.68429  5.38524   1.000 84.76714  ? 147 ARG A HB3  1 
ATOM   2075 H HG2  . ARG A 1 147 ? -29.26455 -6.46065  5.69690   1.000 76.76447  ? 147 ARG A HG2  1 
ATOM   2076 H HG3  . ARG A 1 147 ? -30.01309 -6.45042  4.29512   1.000 76.76447  ? 147 ARG A HG3  1 
ATOM   2077 H HD2  . ARG A 1 147 ? -31.53338 -6.72561  6.08422   1.000 73.59076  ? 147 ARG A HD2  1 
ATOM   2078 H HD3  . ARG A 1 147 ? -31.58204 -7.96539  5.09125   1.000 73.59076  ? 147 ARG A HD3  1 
ATOM   2079 H HE   . ARG A 1 147 ? -29.92074 -8.46070  7.08870   1.000 96.40052  ? 147 ARG A HE   1 
ATOM   2080 H HH11 . ARG A 1 147 ? -33.19987 -8.51204  6.56925   1.000 67.05105  ? 147 ARG A HH11 1 
ATOM   2081 H HH12 . ARG A 1 147 ? -33.50395 -9.49477  7.64656   1.000 67.05105  ? 147 ARG A HH12 1 
ATOM   2082 H HH21 . ARG A 1 147 ? -30.41523 -9.95416  8.68718   1.000 87.60873  ? 147 ARG A HH21 1 
ATOM   2083 H HH22 . ARG A 1 147 ? -31.82774 -10.36422 8.92273   1.000 87.60873  ? 147 ARG A HH22 1 
ATOM   2084 N N    . GLY A 1 148 ? -26.01688 -6.01466  4.24771   1.000 67.40798  ? 148 GLY A N    1 
ATOM   2085 C CA   . GLY A 1 148 ? -24.99094 -5.30434  4.98507   1.000 62.49986  ? 148 GLY A CA   1 
ATOM   2086 C C    . GLY A 1 148 ? -23.67845 -6.06050  5.01043   1.000 69.79396  ? 148 GLY A C    1 
ATOM   2087 O O    . GLY A 1 148 ? -23.04593 -6.25321  3.96827   1.000 79.66207  ? 148 GLY A O    1 
ATOM   2088 H H    . GLY A 1 148 ? -26.16575 -5.70096  3.46092   1.000 81.04811  ? 148 GLY A H    1 
ATOM   2089 H HA2  . GLY A 1 148 ? -24.83892 -4.43952  4.57290   1.000 75.15837  ? 148 GLY A HA2  1 
ATOM   2090 H HA3  . GLY A 1 148 ? -25.28593 -5.17091  5.89944   1.000 75.15837  ? 148 GLY A HA3  1 
ATOM   2091 N N    . ASN A 1 149 ? -23.25387 -6.48820  6.20050   1.000 60.39494  ? 149 ASN A N    1 
ATOM   2092 C CA   . ASN A 1 149 ? -22.08405 -7.33952  6.35405   1.000 64.48053  ? 149 ASN A CA   1 
ATOM   2093 C C    . ASN A 1 149 ? -22.44103 -8.78337  6.67123   1.000 67.89760  ? 149 ASN A C    1 
ATOM   2094 O O    . ASN A 1 149 ? -21.54942 -9.64198  6.66839   1.000 54.67567  ? 149 ASN A O    1 
ATOM   2095 C CB   . ASN A 1 149 ? -21.16852 -6.79113  7.46140   1.000 63.80150  ? 149 ASN A CB   1 
ATOM   2096 C CG   . ASN A 1 149 ? -20.28773 -5.65104  6.98187   1.000 81.69679  ? 149 ASN A CG   1 
ATOM   2097 O OD1  . ASN A 1 149 ? -20.46511 -5.13473  5.87805   1.000 87.93233  ? 149 ASN A OD1  1 
ATOM   2098 N ND2  . ASN A 1 149 ? -19.33092 -5.25222  7.81386   1.000 78.69099  ? 149 ASN A ND2  1 
ATOM   2099 H H    . ASN A 1 149 ? -23.63687 -6.29269  6.94528   1.000 72.63247  ? 149 ASN A H    1 
ATOM   2100 H HA   . ASN A 1 149 ? -21.57909 -7.33076  5.52589   1.000 77.53518  ? 149 ASN A HA   1 
ATOM   2101 H HB2  . ASN A 1 149 ? -21.71661 -6.46094  8.19042   1.000 76.72034  ? 149 ASN A HB2  1 
ATOM   2102 H HB3  . ASN A 1 149 ? -20.59145 -7.50416  7.77679   1.000 76.72034  ? 149 ASN A HB3  1 
ATOM   2103 H HD21 . ASN A 1 149 ? -19.23733 -5.63661  8.57746   1.000 94.58773  ? 149 ASN A HD21 1 
ATOM   2104 H HD22 . ASN A 1 149 ? -18.80545 -4.60978  7.58857   1.000 94.58773  ? 149 ASN A HD22 1 
ATOM   2105 N N    . ASP A 1 150 ? -23.71178 -9.07493  6.92835   1.000 67.77216  ? 150 ASP A N    1 
ATOM   2106 C CA   . ASP A 1 150 ? -24.15213 -10.39734 7.33866   1.000 52.92670  ? 150 ASP A CA   1 
ATOM   2107 C C    . ASP A 1 150 ? -24.81263 -11.12559 6.17731   1.000 63.70051  ? 150 ASP A C    1 
ATOM   2108 O O    . ASP A 1 150 ? -25.61559 -10.54392 5.44228   1.000 58.11545  ? 150 ASP A O    1 
ATOM   2109 C CB   . ASP A 1 150 ? -25.14255 -10.30543 8.50277   1.000 49.77650  ? 150 ASP A CB   1 
ATOM   2110 C CG   . ASP A 1 150 ? -24.56995 -9.58971  9.70655   1.000 81.13075  ? 150 ASP A CG   1 
ATOM   2111 O OD1  . ASP A 1 150 ? -25.03348 -8.47004  10.01127  1.000 91.67259  ? 150 ASP A OD1  1 
ATOM   2112 O OD2  . ASP A 1 150 ? -23.65537 -10.14898 10.34657  1.000 95.20108  ? 150 ASP A OD2  1 
ATOM   2113 H H    . ASP A 1 150 ? -24.35336 -8.50526  6.86964   1.000 81.48514  ? 150 ASP A H    1 
ATOM   2114 H HA   . ASP A 1 150 ? -23.37903 -10.90984 7.62250   1.000 63.67059  ? 150 ASP A HA   1 
ATOM   2115 H HB2  . ASP A 1 150 ? -25.92878 -9.81820  8.21063   1.000 59.89035  ? 150 ASP A HB2  1 
ATOM   2116 H HB3  . ASP A 1 150 ? -25.39091 -11.20195 8.77750   1.000 59.89035  ? 150 ASP A HB3  1 
ATOM   2117 N N    . TYR A 1 151 ? -24.46829 -12.40001 6.01720   1.000 69.12869  ? 151 TYR A N    1 
ATOM   2118 C CA   . TYR A 1 151 ? -25.19754 -13.27761 5.11410   1.000 55.99653  ? 151 TYR A CA   1 
ATOM   2119 C C    . TYR A 1 151 ? -26.44257 -13.80811 5.81623   1.000 43.83710  ? 151 TYR A C    1 
ATOM   2120 O O    . TYR A 1 151 ? -26.45239 -14.01552 7.03307   1.000 54.34123  ? 151 TYR A O    1 
ATOM   2121 C CB   . TYR A 1 151 ? -24.31353 -14.43442 4.65631   1.000 51.83434  ? 151 TYR A CB   1 
ATOM   2122 C CG   . TYR A 1 151 ? -23.23400 -14.03600 3.67197   1.000 61.97132  ? 151 TYR A CG   1 
ATOM   2123 C CD1  . TYR A 1 151 ? -23.52261 -13.22576 2.58180   1.000 72.79201  ? 151 TYR A CD1  1 
ATOM   2124 C CD2  . TYR A 1 151 ? -21.92501 -14.46764 3.83551   1.000 72.69273  ? 151 TYR A CD2  1 
ATOM   2125 C CE1  . TYR A 1 151 ? -22.54024 -12.86069 1.68242   1.000 82.78632  ? 151 TYR A CE1  1 
ATOM   2126 C CE2  . TYR A 1 151 ? -20.93555 -14.10551 2.94096   1.000 85.22430  ? 151 TYR A CE2  1 
ATOM   2127 C CZ   . TYR A 1 151 ? -21.24822 -13.30218 1.86750   1.000 71.79646  ? 151 TYR A CZ   1 
ATOM   2128 O OH   . TYR A 1 151 ? -20.26215 -12.94237 0.97757   1.000 75.60449  ? 151 TYR A OH   1 
ATOM   2129 H H    . TYR A 1 151 ? -23.81255 -12.78079 6.42293   1.000 83.11297  ? 151 TYR A H    1 
ATOM   2130 H HA   . TYR A 1 151 ? -25.47015 -12.79079 4.32063   1.000 67.35438  ? 151 TYR A HA   1 
ATOM   2131 H HB2  . TYR A 1 151 ? -23.87698 -14.81783 5.43305   1.000 62.35975  ? 151 TYR A HB2  1 
ATOM   2132 H HB3  . TYR A 1 151 ? -24.87221 -15.10106 4.22693   1.000 62.35975  ? 151 TYR A HB3  1 
ATOM   2133 H HD1  . TYR A 1 151 ? -24.39297 -12.92357 2.45508   1.000 87.50896  ? 151 TYR A HD1  1 
ATOM   2134 H HD2  . TYR A 1 151 ? -21.70993 -15.01003 4.55970   1.000 87.38981  ? 151 TYR A HD2  1 
ATOM   2135 H HE1  . TYR A 1 151 ? -22.74969 -12.31965 0.95557   1.000 99.50213  ? 151 TYR A HE1  1 
ATOM   2136 H HE2  . TYR A 1 151 ? -20.06299 -14.40300 3.06358   1.000 102.42770 ? 151 TYR A HE2  1 
ATOM   2137 H HH   . TYR A 1 151 ? -19.53629 -13.30806 1.18972   1.000 90.88393  ? 151 TYR A HH   1 
ATOM   2138 N N    . VAL A 1 152 ? -27.50199 -14.02196 5.03819   1.000 49.09320  ? 152 VAL A N    1 
ATOM   2139 C CA   . VAL A 1 152 ? -28.80055 -14.42243 5.56582   1.000 32.58270  ? 152 VAL A CA   1 
ATOM   2140 C C    . VAL A 1 152 ? -29.29161 -15.63535 4.79045   1.000 33.01496  ? 152 VAL A C    1 
ATOM   2141 O O    . VAL A 1 152 ? -29.37477 -15.59527 3.55860   1.000 36.37586  ? 152 VAL A O    1 
ATOM   2142 C CB   . VAL A 1 152 ? -29.83044 -13.27458 5.47369   1.000 38.34479  ? 152 VAL A CB   1 
ATOM   2143 C CG1  . VAL A 1 152 ? -31.18803 -13.72766 6.00185   1.000 39.60530  ? 152 VAL A CG1  1 
ATOM   2144 C CG2  . VAL A 1 152 ? -29.33564 -12.05301 6.23153   1.000 48.65122  ? 152 VAL A CG2  1 
ATOM   2145 H H    . VAL A 1 152 ? -27.49061 -13.93895 4.18228   1.000 59.07039  ? 152 VAL A H    1 
ATOM   2146 H HA   . VAL A 1 152 ? -28.69965 -14.67818 6.49605   1.000 39.25778  ? 152 VAL A HA   1 
ATOM   2147 H HB   . VAL A 1 152 ? -29.94029 -13.02596 4.54255   1.000 46.17228  ? 152 VAL A HB   1 
ATOM   2148 H HG11 . VAL A 1 152 ? -31.65053 -12.96372 6.38053   1.000 47.68490  ? 152 VAL A HG11 1 
ATOM   2149 H HG12 . VAL A 1 152 ? -31.70478 -14.09714 5.26880   1.000 47.68490  ? 152 VAL A HG12 1 
ATOM   2150 H HG13 . VAL A 1 152 ? -31.05189 -14.40348 6.68421   1.000 47.68490  ? 152 VAL A HG13 1 
ATOM   2151 H HG21 . VAL A 1 152 ? -30.00754 -11.35536 6.17918   1.000 58.54001  ? 152 VAL A HG21 1 
ATOM   2152 H HG22 . VAL A 1 152 ? -29.18312 -12.29652 7.15800   1.000 58.54001  ? 152 VAL A HG22 1 
ATOM   2153 H HG23 . VAL A 1 152 ? -28.50794 -11.74593 5.82966   1.000 58.54001  ? 152 VAL A HG23 1 
ATOM   2154 N N    . VAL A 1 153 ? -29.61307 -16.71122 5.51257   1.000 37.06607  ? 153 VAL A N    1 
ATOM   2155 C CA   . VAL A 1 153 ? -30.20741 -17.90513 4.91978   1.000 27.17603  ? 153 VAL A CA   1 
ATOM   2156 C C    . VAL A 1 153 ? -31.71712 -17.71804 4.89196   1.000 30.66966  ? 153 VAL A C    1 
ATOM   2157 O O    . VAL A 1 153 ? -32.32242 -17.36145 5.91032   1.000 34.90759  ? 153 VAL A O    1 
ATOM   2158 C CB   . VAL A 1 153 ? -29.83395 -19.16866 5.71391   1.000 33.70598  ? 153 VAL A CB   1 
ATOM   2159 C CG1  . VAL A 1 153 ? -30.08188 -20.41898 4.87200   1.000 28.21558  ? 153 VAL A CG1  1 
ATOM   2160 C CG2  . VAL A 1 153 ? -28.39462 -19.10987 6.18568   1.000 41.57923  ? 153 VAL A CG2  1 
ATOM   2161 H H    . VAL A 1 153 ? -29.49344 -16.77210 6.36203   1.000 44.63782  ? 153 VAL A H    1 
ATOM   2162 H HA   . VAL A 1 153 ? -29.88052 -18.00948 4.01250   1.000 32.76978  ? 153 VAL A HA   1 
ATOM   2163 H HB   . VAL A 1 153 ? -30.39718 -19.21769 6.50211   1.000 40.60572  ? 153 VAL A HB   1 
ATOM   2164 H HG11 . VAL A 1 153 ? -29.84866 -21.20256 5.39401   1.000 34.01723  ? 153 VAL A HG11 1 
ATOM   2165 H HG12 . VAL A 1 153 ? -31.01939 -20.45284 4.62536   1.000 34.01723  ? 153 VAL A HG12 1 
ATOM   2166 H HG13 . VAL A 1 153 ? -29.53135 -20.37696 4.07447   1.000 34.01723  ? 153 VAL A HG13 1 
ATOM   2167 H HG21 . VAL A 1 153 ? -28.14252 -19.97722 6.53931   1.000 50.05362  ? 153 VAL A HG21 1 
ATOM   2168 H HG22 . VAL A 1 153 ? -27.82521 -18.88068 5.43458   1.000 50.05362  ? 153 VAL A HG22 1 
ATOM   2169 H HG23 . VAL A 1 153 ? -28.31653 -18.43498 6.87801   1.000 50.05362  ? 153 VAL A HG23 1 
ATOM   2170 N N    . ILE A 1 154 ? -32.33144 -17.95994 3.73570   1.000 33.11524  ? 154 ILE A N    1 
ATOM   2171 C CA   . ILE A 1 154 ? -33.77087 -17.79567 3.59966   1.000 31.59059  ? 154 ILE A CA   1 
ATOM   2172 C C    . ILE A 1 154 ? -34.50549 -19.11214 3.37895   1.000 28.61558  ? 154 ILE A C    1 
ATOM   2173 O O    . ILE A 1 154 ? -35.72077 -19.16839 3.62003   1.000 35.77234  ? 154 ILE A O    1 
ATOM   2174 C CB   . ILE A 1 154 ? -34.12318 -16.79627 2.47705   1.000 47.19205  ? 154 ILE A CB   1 
ATOM   2175 C CG1  . ILE A 1 154 ? -33.77889 -17.35033 1.09499   1.000 30.65504  ? 154 ILE A CG1  1 
ATOM   2176 C CG2  . ILE A 1 154 ? -33.39630 -15.47509 2.71465   1.000 34.95354  ? 154 ILE A CG2  1 
ATOM   2177 C CD1  . ILE A 1 154 ? -34.37683 -16.53031 -0.03482  1.000 29.41000  ? 154 ILE A CD1  1 
ATOM   2178 H H    . ILE A 1 154 ? -31.93474 -18.21969 3.01824   1.000 39.89683  ? 154 ILE A H    1 
ATOM   2179 H HA   . ILE A 1 154 ? -34.10424 -17.42564 4.43203   1.000 38.06725  ? 154 ILE A HA   1 
ATOM   2180 H HB   . ILE A 1 154 ? -35.08179 -16.65001 2.50084   1.000 56.78900  ? 154 ILE A HB   1 
ATOM   2181 H HG12 . ILE A 1 154 ? -32.81493 -17.35174 0.98694   1.000 36.94459  ? 154 ILE A HG12 1 
ATOM   2182 H HG13 . ILE A 1 154 ? -34.12208 -18.25476 1.02333   1.000 36.94459  ? 154 ILE A HG13 1 
ATOM   2183 H HG21 . ILE A 1 154 ? -33.71542 -14.81957 2.07484   1.000 42.10279  ? 154 ILE A HG21 1 
ATOM   2184 H HG22 . ILE A 1 154 ? -33.57911 -15.17205 3.61779   1.000 42.10279  ? 154 ILE A HG22 1 
ATOM   2185 H HG23 . ILE A 1 154 ? -32.44327 -15.61370 2.59880   1.000 42.10279  ? 154 ILE A HG23 1 
ATOM   2186 H HD11 . ILE A 1 154 ? -34.16734 -16.95739 -0.88017  1.000 35.45054  ? 154 ILE A HD11 1 
ATOM   2187 H HD12 . ILE A 1 154 ? -35.33853 -16.48420 0.08311   1.000 35.45054  ? 154 ILE A HD12 1 
ATOM   2188 H HD13 . ILE A 1 154 ? -33.99764 -15.63779 -0.01222  1.000 35.45054  ? 154 ILE A HD13 1 
ATOM   2189 N N    . GLY A 1 155 ? -33.82521 -20.16596 2.93740   1.000 35.41765  ? 155 GLY A N    1 
ATOM   2190 C CA   . GLY A 1 155 ? -34.48895 -21.44681 2.79179   1.000 34.15419  ? 155 GLY A CA   1 
ATOM   2191 C C    . GLY A 1 155 ? -33.63911 -22.42443 2.00657   1.000 28.85663  ? 155 GLY A C    1 
ATOM   2192 O O    . GLY A 1 155 ? -32.43810 -22.22073 1.82654   1.000 30.91192  ? 155 GLY A O    1 
ATOM   2193 H H    . GLY A 1 155 ? -32.99311 -20.16172 2.72016   1.000 42.65973  ? 155 GLY A H    1 
ATOM   2194 H HA2  . GLY A 1 155 ? -34.66415 -21.82388 3.66816   1.000 41.14357  ? 155 GLY A HA2  1 
ATOM   2195 H HA3  . GLY A 1 155 ? -35.33113 -21.32566 2.32601   1.000 41.14357  ? 155 GLY A HA3  1 
ATOM   2196 N N    . VAL A 1 156 ? -34.29140 -23.48744 1.53912   1.000 26.03683  ? 156 VAL A N    1 
ATOM   2197 C CA   . VAL A 1 156 ? -33.62113 -24.57322 0.83784   1.000 45.76719  ? 156 VAL A CA   1 
ATOM   2198 C C    . VAL A 1 156 ? -34.37539 -24.88713 -0.44576  1.000 31.99327  ? 156 VAL A C    1 
ATOM   2199 O O    . VAL A 1 156 ? -35.59644 -24.72312 -0.52873  1.000 29.35606  ? 156 VAL A O    1 
ATOM   2200 C CB   . VAL A 1 156 ? -33.50929 -25.82893 1.73029   1.000 29.28822  ? 156 VAL A CB   1 
ATOM   2201 C CG1  . VAL A 1 156 ? -32.76144 -25.49750 3.01526   1.000 32.64922  ? 156 VAL A CG1  1 
ATOM   2202 C CG2  . VAL A 1 156 ? -34.89246 -26.38873 2.04735   1.000 34.90565  ? 156 VAL A CG2  1 
ATOM   2203 H H    . VAL A 1 156 ? -35.13998 -23.60198 1.61909   1.000 31.40274  ? 156 VAL A H    1 
ATOM   2204 H HA   . VAL A 1 156 ? -32.72820 -24.28922 0.58701   1.000 55.07917  ? 156 VAL A HA   1 
ATOM   2205 H HB   . VAL A 1 156 ? -33.01162 -26.51041 1.25194   1.000 35.30441  ? 156 VAL A HB   1 
ATOM   2206 H HG11 . VAL A 1 156 ? -32.64283 -26.31083 3.53037   1.000 39.33760  ? 156 VAL A HG11 1 
ATOM   2207 H HG12 . VAL A 1 156 ? -31.89694 -25.12013 2.78916   1.000 39.33760  ? 156 VAL A HG12 1 
ATOM   2208 H HG13 . VAL A 1 156 ? -33.27943 -24.85541 3.52547   1.000 39.33760  ? 156 VAL A HG13 1 
ATOM   2209 H HG21 . VAL A 1 156 ? -34.80641 -27.07903 2.72335   1.000 42.04532  ? 156 VAL A HG21 1 
ATOM   2210 H HG22 . VAL A 1 156 ? -35.45557 -25.67109 2.37720   1.000 42.04532  ? 156 VAL A HG22 1 
ATOM   2211 H HG23 . VAL A 1 156 ? -35.27441 -26.76372 1.23841   1.000 42.04532  ? 156 VAL A HG23 1 
ATOM   2212 N N    . HIS A 1 157 ? -33.63490 -25.34492 -1.45468  1.000 30.34633  ? 157 HIS A N    1 
ATOM   2213 C CA   . HIS A 1 157 ? -34.23321 -25.65274 -2.74785  1.000 37.39105  ? 157 HIS A CA   1 
ATOM   2214 C C    . HIS A 1 157 ? -35.10788 -26.89515 -2.63719  1.000 31.85765  ? 157 HIS A C    1 
ATOM   2215 O O    . HIS A 1 157 ? -34.69697 -27.90576 -2.05815  1.000 32.25967  ? 157 HIS A O    1 
ATOM   2216 C CB   . HIS A 1 157 ? -33.14425 -25.86180 -3.80195  1.000 32.77693  ? 157 HIS A CB   1 
ATOM   2217 C CG   . HIS A 1 157 ? -33.67526 -26.16316 -5.17040  1.000 39.93094  ? 157 HIS A CG   1 
ATOM   2218 N ND1  . HIS A 1 157 ? -34.23338 -25.19935 -5.98212  1.000 23.58926  ? 157 HIS A ND1  1 
ATOM   2219 C CD2  . HIS A 1 157 ? -33.73321 -27.32170 -5.86882  1.000 30.82617  ? 157 HIS A CD2  1 
ATOM   2220 C CE1  . HIS A 1 157 ? -34.61593 -25.75151 -7.12011  1.000 38.71090  ? 157 HIS A CE1  1 
ATOM   2221 N NE2  . HIS A 1 157 ? -34.32190 -27.03861 -7.07737  1.000 42.26262  ? 157 HIS A NE2  1 
ATOM   2222 H H    . HIS A 1 157 ? -32.78730 -25.48482 -1.41456  1.000 36.57413  ? 157 HIS A H    1 
ATOM   2223 H HA   . HIS A 1 157 ? -34.78847 -24.90966 -3.03142  1.000 45.02781  ? 157 HIS A HA   1 
ATOM   2224 H HB2  . HIS A 1 157 ? -32.61078 -25.05399 -3.86315  1.000 39.49085  ? 157 HIS A HB2  1 
ATOM   2225 H HB3  . HIS A 1 157 ? -32.58684 -26.60770 -3.53027  1.000 39.49085  ? 157 HIS A HB3  1 
ATOM   2226 H HD2  . HIS A 1 157 ? -33.43095 -28.15370 -5.58365  1.000 37.14994  ? 157 HIS A HD2  1 
ATOM   2227 H HE1  . HIS A 1 157 ? -35.02276 -25.30937 -7.82997  1.000 46.61162  ? 157 HIS A HE1  1 
ATOM   2228 H HE2  . HIS A 1 157 ? -34.47428 -27.60713 -7.70440  1.000 50.87369  ? 157 HIS A HE2  1 
ATOM   2229 N N    . THR A 1 158 ? -36.31809 -26.82128 -3.19647  1.000 39.71438  ? 158 THR A N    1 
ATOM   2230 C CA   . THR A 1 158 ? -37.25295 -27.94146 -3.11747  1.000 28.37320  ? 158 THR A CA   1 
ATOM   2231 C C    . THR A 1 158 ? -37.96708 -28.27525 -4.42081  1.000 23.65923  ? 158 THR A C    1 
ATOM   2232 O O    . THR A 1 158 ? -38.52764 -29.37186 -4.51618  1.000 29.27244  ? 158 THR A O    1 
ATOM   2233 C CB   . THR A 1 158 ? -38.31155 -27.67495 -2.03651  1.000 33.12248  ? 158 THR A CB   1 
ATOM   2234 O OG1  . THR A 1 158 ? -39.09579 -28.85581 -1.82147  1.000 49.76592  ? 158 THR A OG1  1 
ATOM   2235 C CG2  . THR A 1 158 ? -39.22804 -26.53703 -2.45506  1.000 37.23779  ? 158 THR A CG2  1 
ATOM   2236 H H    . THR A 1 158 ? -36.61772 -26.13771 -3.62374  1.000 47.81580  ? 158 THR A H    1 
ATOM   2237 H HA   . THR A 1 158 ? -36.75201 -28.73146 -2.86086  1.000 34.20638  ? 158 THR A HA   1 
ATOM   2238 H HB   . THR A 1 158 ? -37.86836 -27.42681 -1.21012  1.000 39.90551  ? 158 THR A HB   1 
ATOM   2239 H HG1  . THR A 1 158 ? -39.50884 -29.05831 -2.52430  1.000 59.87765  ? 158 THR A HG1  1 
ATOM   2240 H HG21 . THR A 1 158 ? -39.75261 -26.23727 -1.69619  1.000 44.84389  ? 158 THR A HG21 1 
ATOM   2241 H HG22 . THR A 1 158 ? -38.70231 -25.79293 -2.78796  1.000 44.84389  ? 158 THR A HG22 1 
ATOM   2242 H HG23 . THR A 1 158 ? -39.82937 -26.83573 -3.15512  1.000 44.84389  ? 158 THR A HG23 1 
ATOM   2243 N N    . ALA A 1 159 ? -37.98401 -27.40524 -5.42584  1.000 21.19614  ? 159 ALA A N    1 
ATOM   2244 C CA   . ALA A 1 159 ? -38.71480 -27.70821 -6.65029  1.000 36.05166  ? 159 ALA A CA   1 
ATOM   2245 C C    . ALA A 1 159 ? -38.34436 -26.69376 -7.72168  1.000 26.06127  ? 159 ALA A C    1 
ATOM   2246 O O    . ALA A 1 159 ? -37.73823 -25.65624 -7.44334  1.000 32.40806  ? 159 ALA A O    1 
ATOM   2247 C CB   . ALA A 1 159 ? -40.22901 -27.71039 -6.41357  1.000 34.88586  ? 159 ALA A CB   1 
ATOM   2248 H H    . ALA A 1 159 ? -37.58524 -26.64329 -5.42209  1.000 25.59391  ? 159 ALA A H    1 
ATOM   2249 H HA   . ALA A 1 159 ? -38.44022 -28.58432 -6.96326  1.000 43.42053  ? 159 ALA A HA   1 
ATOM   2250 H HB1  . ALA A 1 159 ? -40.67871 -27.91858 -7.24743  1.000 42.02157  ? 159 ALA A HB1  1 
ATOM   2251 H HB2  . ALA A 1 159 ? -40.44330 -28.38061 -5.74589  1.000 42.02157  ? 159 ALA A HB2  1 
ATOM   2252 H HB3  . ALA A 1 159 ? -40.50106 -26.83334 -6.10105  1.000 42.02157  ? 159 ALA A HB3  1 
ATOM   2253 N N    . ALA A 1 160 ? -38.72125 -27.01508 -8.95877  1.000 39.99835  ? 160 ALA A N    1 
ATOM   2254 C CA   . ALA A 1 160 ? -38.48701 -26.13966 -10.10009 1.000 40.21091  ? 160 ALA A CA   1 
ATOM   2255 C C    . ALA A 1 160 ? -39.45180 -26.53925 -11.20490 1.000 26.95704  ? 160 ALA A C    1 
ATOM   2256 O O    . ALA A 1 160 ? -39.57118 -27.72677 -11.52282 1.000 52.20317  ? 160 ALA A O    1 
ATOM   2257 C CB   . ALA A 1 160 ? -37.04078 -26.23606 -10.59222 1.000 37.90897  ? 160 ALA A CB   1 
ATOM   2258 H H    . ALA A 1 160 ? -39.12136 -27.74798 -9.16461  1.000 48.15657  ? 160 ALA A H    1 
ATOM   2259 H HA   . ALA A 1 160 ? -38.65606 -25.21835 -9.84808  1.000 48.41164  ? 160 ALA A HA   1 
ATOM   2260 H HB1  . ALA A 1 160 ? -36.92157 -25.63272 -11.34234 1.000 45.64930  ? 160 ALA A HB1  1 
ATOM   2261 H HB2  . ALA A 1 160 ? -36.44393 -25.98698 -9.86929  1.000 45.64930  ? 160 ALA A HB2  1 
ATOM   2262 H HB3  . ALA A 1 160 ? -36.86172 -27.14813 -10.86963 1.000 45.64930  ? 160 ALA A HB3  1 
ATOM   2263 N N    . ALA A 1 161 ? -40.13734 -25.55747 -11.78133 1.000 40.60070  ? 161 ALA A N    1 
ATOM   2264 C CA   . ALA A 1 161 ? -41.14849 -25.85368 -12.78412 1.000 43.38348  ? 161 ALA A CA   1 
ATOM   2265 C C    . ALA A 1 161 ? -40.49690 -26.37006 -14.06012 1.000 57.66687  ? 161 ALA A C    1 
ATOM   2266 O O    . ALA A 1 161 ? -39.36694 -26.00936 -14.39926 1.000 60.59040  ? 161 ALA A O    1 
ATOM   2267 C CB   . ALA A 1 161 ? -41.98570 -24.61207 -13.08607 1.000 41.67685  ? 161 ALA A CB   1 
ATOM   2268 H H    . ALA A 1 161 ? -40.03597 -24.72078 -11.61021 1.000 48.87938  ? 161 ALA A H    1 
ATOM   2269 H HA   . ALA A 1 161 ? -41.74622 -26.53977 -12.44809 1.000 52.21872  ? 161 ALA A HA   1 
ATOM   2270 H HB1  . ALA A 1 161 ? -42.64251 -24.83158 -13.76528 1.000 50.17076  ? 161 ALA A HB1  1 
ATOM   2271 H HB2  . ALA A 1 161 ? -42.43255 -24.32724 -12.27361 1.000 50.17076  ? 161 ALA A HB2  1 
ATOM   2272 H HB3  . ALA A 1 161 ? -41.40125 -23.90738 -13.40659 1.000 50.17076  ? 161 ALA A HB3  1 
ATOM   2273 N N    . ARG A 1 162 ? -41.21971 -27.23291 -14.76737 1.000 64.00850  ? 162 ARG A N    1 
ATOM   2274 C CA   . ARG A 1 162 ? -40.70033 -27.80277 -16.00364 1.000 68.25744  ? 162 ARG A CA   1 
ATOM   2275 C C    . ARG A 1 162 ? -40.85429 -26.85663 -17.18477 1.000 63.59851  ? 162 ARG A C    1 
ATOM   2276 O O    . ARG A 1 162 ? -40.42055 -27.19700 -18.28938 1.000 62.47142  ? 162 ARG A O    1 
ATOM   2277 C CB   . ARG A 1 162 ? -41.38884 -29.14036 -16.29387 1.000 59.24021  ? 162 ARG A CB   1 
ATOM   2278 C CG   . ARG A 1 162 ? -40.56657 -30.13068 -17.13632 1.000 60.73329  ? 162 ARG A CG   1 
ATOM   2279 C CD   . ARG A 1 162 ? -39.14569 -30.34513 -16.61726 1.000 85.76695  ? 162 ARG A CD   1 
ATOM   2280 N NE   . ARG A 1 162 ? -39.02738 -31.46122 -15.68968 1.000 98.79934  ? 162 ARG A NE   1 
ATOM   2281 C CZ   . ARG A 1 162 ? -37.95216 -31.71299 -14.95789 1.000 80.65373  ? 162 ARG A CZ   1 
ATOM   2282 N NH1  . ARG A 1 162 ? -36.93902 -30.86587 -14.90971 1.000 86.22931  ? 162 ARG A NH1  1 
ATOM   2283 N NH2  . ARG A 1 162 ? -37.88648 -32.84854 -14.26747 1.000 74.84489  ? 162 ARG A NH2  1 
ATOM   2284 H H    . ARG A 1 162 ? -42.00803 -27.50158 -14.55293 1.000 76.96874  ? 162 ARG A H    1 
ATOM   2285 H HA   . ARG A 1 162 ? -39.75390 -27.98741 -15.89838 1.000 82.06746  ? 162 ARG A HA   1 
ATOM   2286 H HB2  . ARG A 1 162 ? -41.58626 -29.57296 -15.44842 1.000 71.24679  ? 162 ARG A HB2  1 
ATOM   2287 H HB3  . ARG A 1 162 ? -42.21169 -28.96299 -16.77589 1.000 71.24679  ? 162 ARG A HB3  1 
ATOM   2288 H HG2  . ARG A 1 162 ? -41.01498 -30.99081 -17.13445 1.000 73.03849  ? 162 ARG A HG2  1 
ATOM   2289 H HG3  . ARG A 1 162 ? -40.50215 -29.79209 -18.04302 1.000 73.03849  ? 162 ARG A HG3  1 
ATOM   2290 H HD2  . ARG A 1 162 ? -38.56053 -30.52233 -17.37032 1.000 103.07888 ? 162 ARG A HD2  1 
ATOM   2291 H HD3  . ARG A 1 162 ? -38.85697 -29.54313 -16.15430 1.000 103.07888 ? 162 ARG A HD3  1 
ATOM   2292 H HE   . ARG A 1 162 ? -39.69967 -31.99184 -15.61176 1.000 118.71775 ? 162 ARG A HE   1 
ATOM   2293 H HH11 . ARG A 1 162 ? -36.96921 -30.13338 -15.35931 1.000 103.63372 ? 162 ARG A HH11 1 
ATOM   2294 H HH12 . ARG A 1 162 ? -36.24950 -31.04708 -14.42874 1.000 103.63372 ? 162 ARG A HH12 1 
ATOM   2295 H HH21 . ARG A 1 162 ? -38.53759 -33.40946 -14.29938 1.000 89.97240  ? 162 ARG A HH21 1 
ATOM   2296 H HH22 . ARG A 1 162 ? -37.19291 -33.02155 -13.78931 1.000 89.97240  ? 162 ARG A HH22 1 
ATOM   2297 N N    . GLY A 1 163 ? -41.45058 -25.68539 -16.98014 1.000 58.79601  ? 163 GLY A N    1 
ATOM   2298 C CA   . GLY A 1 163 ? -41.49602 -24.67592 -18.01603 1.000 53.25359  ? 163 GLY A CA   1 
ATOM   2299 C C    . GLY A 1 163 ? -40.24182 -23.82864 -18.01836 1.000 74.46610  ? 163 GLY A C    1 
ATOM   2300 O O    . GLY A 1 163 ? -39.12963 -24.35046 -18.14646 1.000 84.64893  ? 163 GLY A O    1 
ATOM   2301 H H    . GLY A 1 163 ? -41.83552 -25.45609 -16.24607 1.000 70.71375  ? 163 GLY A H    1 
ATOM   2302 H HA2  . GLY A 1 163 ? -41.58270 -25.10358 -18.88234 1.000 64.06284  ? 163 GLY A HA2  1 
ATOM   2303 H HA3  . GLY A 1 163 ? -42.26082 -24.09700 -17.87170 1.000 64.06284  ? 163 GLY A HA3  1 
ATOM   2304 N N    . GLY A 1 164 ? -40.40873 -22.51950 -17.86400 1.000 75.46541  ? 164 GLY A N    1 
ATOM   2305 C CA   . GLY A 1 164 ? -39.28078 -21.61373 -17.85833 1.000 69.09718  ? 164 GLY A CA   1 
ATOM   2306 C C    . GLY A 1 164 ? -38.52435 -21.59640 -16.54744 1.000 73.46319  ? 164 GLY A C    1 
ATOM   2307 O O    . GLY A 1 164 ? -38.38570 -22.62675 -15.88113 1.000 60.09743  ? 164 GLY A O    1 
ATOM   2308 H H    . GLY A 1 164 ? -41.17079 -22.13455 -17.76062 1.000 90.71703  ? 164 GLY A H    1 
ATOM   2309 H HA2  . GLY A 1 164 ? -38.66251 -21.87437 -18.55884 1.000 83.07516  ? 164 GLY A HA2  1 
ATOM   2310 H HA3  . GLY A 1 164 ? -39.59701 -20.71390 -18.03494 1.000 83.07516  ? 164 GLY A HA3  1 
ATOM   2311 N N    . ASN A 1 165 ? -38.02964 -20.41912 -16.17126 1.000 80.43996  ? 165 ASN A N    1 
ATOM   2312 C CA   . ASN A 1 165 ? -37.16424 -20.26344 -15.00386 1.000 63.03958  ? 165 ASN A CA   1 
ATOM   2313 C C    . ASN A 1 165 ? -38.05767 -19.99148 -13.79905 1.000 60.78824  ? 165 ASN A C    1 
ATOM   2314 O O    . ASN A 1 165 ? -38.53129 -18.86898 -13.60630 1.000 60.42612  ? 165 ASN A O    1 
ATOM   2315 C CB   . ASN A 1 165 ? -36.14897 -19.13513 -15.21227 1.000 40.87508  ? 165 ASN A CB   1 
ATOM   2316 C CG   . ASN A 1 165 ? -35.10362 -19.47006 -16.28631 1.000 78.75264  ? 165 ASN A CG   1 
ATOM   2317 O OD1  . ASN A 1 165 ? -35.30697 -20.34344 -17.11578 1.000 92.55151  ? 165 ASN A OD1  1 
ATOM   2318 N ND2  . ASN A 1 165 ? -33.97363 -18.74876 -16.26031 1.000 94.75242  ? 165 ASN A ND2  1 
ATOM   2319 H H    . ASN A 1 165 ? -38.18392 -19.68077 -16.58435 1.000 96.68649  ? 165 ASN A H    1 
ATOM   2320 H HA   . ASN A 1 165 ? -36.67162 -21.08598 -14.85670 1.000 75.80604  ? 165 ASN A HA   1 
ATOM   2321 H HB2  . ASN A 1 165 ? -36.61928 -18.33373 -15.49059 1.000 49.20863  ? 165 ASN A HB2  1 
ATOM   2322 H HB3  . ASN A 1 165 ? -35.68109 -18.97248 -14.37828 1.000 49.20863  ? 165 ASN A HB3  1 
ATOM   2323 H HD21 . ASN A 1 165 ? -33.86671 -18.13844 -15.66392 1.000 113.86145 ? 165 ASN A HD21 1 
ATOM   2324 H HD22 . ASN A 1 165 ? -33.35579 -18.89643 -16.84002 1.000 113.86145 ? 165 ASN A HD22 1 
ATOM   2325 N N    . THR A 1 166 ? -38.30373 -21.02518 -12.99497 1.000 52.76086  ? 166 THR A N    1 
ATOM   2326 C CA   . THR A 1 166 ? -39.04576 -20.87505 -11.74491 1.000 49.51049  ? 166 THR A CA   1 
ATOM   2327 C C    . THR A 1 166 ? -38.51796 -21.92216 -10.77373 1.000 26.17658  ? 166 THR A C    1 
ATOM   2328 O O    . THR A 1 166 ? -38.73399 -23.12131 -10.97610 1.000 35.06974  ? 166 THR A O    1 
ATOM   2329 C CB   . THR A 1 166 ? -40.55105 -21.03303 -11.95829 1.000 57.06800  ? 166 THR A CB   1 
ATOM   2330 O OG1  . THR A 1 166 ? -41.05132 -19.91365 -12.70056 1.000 62.41980  ? 166 THR A OG1  1 
ATOM   2331 C CG2  . THR A 1 166 ? -41.28893 -21.11302 -10.62236 1.000 29.85333  ? 166 THR A CG2  1 
ATOM   2332 H H    . THR A 1 166 ? -38.04895 -21.83126 -13.15286 1.000 63.47157  ? 166 THR A H    1 
ATOM   2333 H HA   . THR A 1 166 ? -38.88637 -19.99106 -11.37877 1.000 59.57112  ? 166 THR A HA   1 
ATOM   2334 H HB   . THR A 1 166 ? -40.71659 -21.85408 -12.44755 1.000 68.64014  ? 166 THR A HB   1 
ATOM   2335 H HG1  . THR A 1 166 ? -40.94974 -19.20693 -12.25802 1.000 75.06230  ? 166 THR A HG1  1 
ATOM   2336 H HG21 . THR A 1 166 ? -42.23749 -20.96195 -10.75771 1.000 35.98254  ? 166 THR A HG21 1 
ATOM   2337 H HG22 . THR A 1 166 ? -41.16316 -21.98929 -10.22583 1.000 35.98254  ? 166 THR A HG22 1 
ATOM   2338 H HG23 . THR A 1 166 ? -40.94670 -20.43991 -10.01350 1.000 35.98254  ? 166 THR A HG23 1 
ATOM   2339 N N    . VAL A 1 167 ? -37.81938 -21.47010 -9.73691  1.000 38.50106  ? 167 VAL A N    1 
ATOM   2340 C CA   . VAL A 1 167 ? -37.37197 -22.32988 -8.65334  1.000 39.50866  ? 167 VAL A CA   1 
ATOM   2341 C C    . VAL A 1 167 ? -38.22097 -22.02760 -7.42630  1.000 33.07332  ? 167 VAL A C    1 
ATOM   2342 O O    . VAL A 1 167 ? -38.78524 -20.93889 -7.27692  1.000 28.49745  ? 167 VAL A O    1 
ATOM   2343 C CB   . VAL A 1 167 ? -35.87439 -22.14116 -8.33885  1.000 35.76661  ? 167 VAL A CB   1 
ATOM   2344 C CG1  . VAL A 1 167 ? -35.01738 -22.81055 -9.40240  1.000 33.45109  ? 167 VAL A CG1  1 
ATOM   2345 C CG2  . VAL A 1 167 ? -35.53849 -20.66079 -8.23165  1.000 35.18728  ? 167 VAL A CG2  1 
ATOM   2346 H H    . VAL A 1 167 ? -37.58765 -20.64778 -9.63844  1.000 46.35982  ? 167 VAL A H    1 
ATOM   2347 H HA   . VAL A 1 167 ? -37.50740 -23.25693 -8.90460  1.000 47.56893  ? 167 VAL A HA   1 
ATOM   2348 H HB   . VAL A 1 167 ? -35.67636 -22.55960 -7.48644  1.000 43.07847  ? 167 VAL A HB   1 
ATOM   2349 H HG11 . VAL A 1 167 ? -34.08184 -22.66098 -9.19434  1.000 40.29985  ? 167 VAL A HG11 1 
ATOM   2350 H HG12 . VAL A 1 167 ? -35.20698 -23.76182 -9.40812  1.000 40.29985  ? 167 VAL A HG12 1 
ATOM   2351 H HG13 . VAL A 1 167 ? -35.22953 -22.42577 -10.26718 1.000 40.29985  ? 167 VAL A HG13 1 
ATOM   2352 H HG21 . VAL A 1 167 ? -34.63382 -20.56582 -7.89484  1.000 42.38327  ? 167 VAL A HG21 1 
ATOM   2353 H HG22 . VAL A 1 167 ? -35.60832 -20.25666 -9.11068  1.000 42.38327  ? 167 VAL A HG22 1 
ATOM   2354 H HG23 . VAL A 1 167 ? -36.16423 -20.23828 -7.62268  1.000 42.38327  ? 167 VAL A HG23 1 
ATOM   2355 N N    . ILE A 1 168 ? -38.30831 -23.00974 -6.53415  1.000 30.13737  ? 168 ILE A N    1 
ATOM   2356 C CA   . ILE A 1 168 ? -39.05928 -22.87919 -5.29409  1.000 25.00602  ? 168 ILE A CA   1 
ATOM   2357 C C    . ILE A 1 168 ? -38.09334 -23.02205 -4.12652  1.000 34.88124  ? 168 ILE A C    1 
ATOM   2358 O O    . ILE A 1 168 ? -37.35253 -24.00845 -4.04071  1.000 38.08437  ? 168 ILE A O    1 
ATOM   2359 C CB   . ILE A 1 168 ? -40.19043 -23.91778 -5.19515  1.000 37.86134  ? 168 ILE A CB   1 
ATOM   2360 C CG1  . ILE A 1 168 ? -41.13445 -23.80325 -6.39542  1.000 39.78894  ? 168 ILE A CG1  1 
ATOM   2361 C CG2  . ILE A 1 168 ? -40.94607 -23.72925 -3.89415  1.000 26.40661  ? 168 ILE A CG2  1 
ATOM   2362 C CD1  . ILE A 1 168 ? -41.72167 -22.42306 -6.59973  1.000 32.25633  ? 168 ILE A CD1  1 
ATOM   2363 H H    . ILE A 1 168 ? -37.93187 -23.77709 -6.62935  1.000 36.32338  ? 168 ILE A H    1 
ATOM   2364 H HA   . ILE A 1 168 ? -39.45472 -21.99422 -5.25737  1.000 30.16576  ? 168 ILE A HA   1 
ATOM   2365 H HB   . ILE A 1 168 ? -39.80133 -24.80625 -5.20645  1.000 45.59214  ? 168 ILE A HB   1 
ATOM   2366 H HG12 . ILE A 1 168 ? -40.64278 -24.03469 -7.19891  1.000 47.90527  ? 168 ILE A HG12 1 
ATOM   2367 H HG13 . ILE A 1 168 ? -41.87225 -24.42008 -6.26870  1.000 47.90527  ? 168 ILE A HG13 1 
ATOM   2368 H HG21 . ILE A 1 168 ? -41.80059 -24.18400 -3.95651  1.000 31.84648  ? 168 ILE A HG21 1 
ATOM   2369 H HG22 . ILE A 1 168 ? -40.42368 -24.10485 -3.16825  1.000 31.84648  ? 168 ILE A HG22 1 
ATOM   2370 H HG23 . ILE A 1 168 ? -41.08607 -22.78110 -3.74480  1.000 31.84648  ? 168 ILE A HG23 1 
ATOM   2371 H HD11 . ILE A 1 168 ? -42.42026 -22.47327 -7.27082  1.000 38.86614  ? 168 ILE A HD11 1 
ATOM   2372 H HD12 . ILE A 1 168 ? -42.09190 -22.10985 -5.75966  1.000 38.86614  ? 168 ILE A HD12 1 
ATOM   2373 H HD13 . ILE A 1 168 ? -41.02038 -21.82227 -6.89660  1.000 38.86614  ? 168 ILE A HD13 1 
ATOM   2374 N N    . CYS A 1 169 ? -38.10409 -22.03501 -3.23693  1.000 27.44231  ? 169 CYS A N    1 
ATOM   2375 C CA   . CYS A 1 169 ? -37.30038 -22.02403 -2.01851  1.000 35.15171  ? 169 CYS A CA   1 
ATOM   2376 C C    . CYS A 1 169 ? -38.24844 -22.25211 -0.84568  1.000 45.28836  ? 169 CYS A C    1 
ATOM   2377 O O    . CYS A 1 169 ? -39.11580 -21.41595 -0.57065  1.000 32.16062  ? 169 CYS A O    1 
ATOM   2378 C CB   . CYS A 1 169 ? -36.54757 -20.70122 -1.89811  1.000 29.51077  ? 169 CYS A CB   1 
ATOM   2379 S SG   . CYS A 1 169 ? -35.76856 -20.38096 -0.30746  1.000 37.44565  ? 169 CYS A SG   1 
ATOM   2380 H H    . CYS A 1 169 ? -38.58994 -21.33036 -3.32076  1.000 33.08931  ? 169 CYS A H    1 
ATOM   2381 H HA   . CYS A 1 169 ? -36.64793 -22.74176 -2.02682  1.000 42.34059  ? 169 CYS A HA   1 
ATOM   2382 H HB2  . CYS A 1 169 ? -35.84661 -20.68912 -2.56849  1.000 35.57146  ? 169 CYS A HB2  1 
ATOM   2383 H HB3  . CYS A 1 169 ? -37.17481 -19.97944 -2.06090  1.000 35.57146  ? 169 CYS A HB3  1 
ATOM   2384 H HG   . CYS A 1 169 ? -34.96834 -21.24656 -0.08300  1.000 45.09333  ? 169 CYS A HG   1 
ATOM   2385 N N    . ALA A 1 170 ? -38.10469 -23.39284 -0.17309  1.000 40.96027  ? 170 ALA A N    1 
ATOM   2386 C CA   . ALA A 1 170 ? -38.95271 -23.71378 0.96984   1.000 28.00819  ? 170 ALA A CA   1 
ATOM   2387 C C    . ALA A 1 170 ? -38.46565 -22.95539 2.20039   1.000 27.60227  ? 170 ALA A C    1 
ATOM   2388 O O    . ALA A 1 170 ? -37.26476 -22.93479 2.48871   1.000 27.39129  ? 170 ALA A O    1 
ATOM   2389 C CB   . ALA A 1 170 ? -38.94915 -25.21908 1.22762   1.000 43.74529  ? 170 ALA A CB   1 
ATOM   2390 H H    . ALA A 1 170 ? -37.52234 -23.99746 -0.35994  1.000 49.31087  ? 170 ALA A H    1 
ATOM   2391 H HA   . ALA A 1 170 ? -39.86662 -23.44495 0.78712   1.000 33.76837  ? 170 ALA A HA   1 
ATOM   2392 H HB1  . ALA A 1 170 ? -39.51622 -25.41008 1.99107   1.000 52.65288  ? 170 ALA A HB1  1 
ATOM   2393 H HB2  . ALA A 1 170 ? -39.28826 -25.67492 0.44142   1.000 52.65288  ? 170 ALA A HB2  1 
ATOM   2394 H HB3  . ALA A 1 170 ? -38.04076 -25.50605 1.41030   1.000 52.65288  ? 170 ALA A HB3  1 
ATOM   2395 N N    . THR A 1 171 ? -39.39616 -22.34023 2.92894   1.000 33.78739  ? 171 THR A N    1 
ATOM   2396 C CA   . THR A 1 171 ? -39.05758 -21.37546 3.96661   1.000 50.05160  ? 171 THR A CA   1 
ATOM   2397 C C    . THR A 1 171 ? -39.59306 -21.81556 5.33013   1.000 29.20059  ? 171 THR A C    1 
ATOM   2398 O O    . THR A 1 171 ? -40.10879 -22.92413 5.49264   1.000 38.19958  ? 171 THR A O    1 
ATOM   2399 C CB   . THR A 1 171 ? -39.60204 -19.98857 3.60415   1.000 24.80568  ? 171 THR A CB   1 
ATOM   2400 O OG1  . THR A 1 171 ? -41.03425 -20.04358 3.50546   1.000 37.65158  ? 171 THR A OG1  1 
ATOM   2401 C CG2  . THR A 1 171 ? -39.02438 -19.52181 2.28468   1.000 28.39803  ? 171 THR A CG2  1 
ATOM   2402 H H    . THR A 1 171 ? -40.24141 -22.46933 2.83678   1.000 40.70341  ? 171 THR A H    1 
ATOM   2403 H HA   . THR A 1 171 ? -38.08947 -21.34721 4.02014   1.000 60.22046  ? 171 THR A HA   1 
ATOM   2404 H HB   . THR A 1 171 ? -39.35086 -19.35155 4.29118   1.000 29.92535  ? 171 THR A HB   1 
ATOM   2405 H HG1  . THR A 1 171 ? -41.33939 -19.28163 3.32679   1.000 45.34044  ? 171 THR A HG1  1 
ATOM   2406 H HG21 . THR A 1 171 ? -39.38479 -18.65126 2.05414   1.000 34.23617  ? 171 THR A HG21 1 
ATOM   2407 H HG22 . THR A 1 171 ? -38.05887 -19.45551 2.35013   1.000 34.23617  ? 171 THR A HG22 1 
ATOM   2408 H HG23 . THR A 1 171 ? -39.24977 -20.15184 1.58243   1.000 34.23617  ? 171 THR A HG23 1 
ATOM   2409 N N    . GLN A 1 172 ? -39.47597 -20.91445 6.30747   1.000 84.14931  ? 172 GLN A N    1 
ATOM   2410 C CA   . GLN A 1 172 ? -39.89478 -21.16529 7.68499   1.000 64.26465  ? 172 GLN A CA   1 
ATOM   2411 C C    . GLN A 1 172 ? -39.04022 -22.27054 8.28899   1.000 60.21646  ? 172 GLN A C    1 
ATOM   2412 O O    . GLN A 1 172 ? -37.86104 -22.06399 8.56733   1.000 80.06842  ? 172 GLN A O    1 
ATOM   2413 C CB   . GLN A 1 172 ? -41.37579 -21.53200 7.75126   1.000 44.81291  ? 172 GLN A CB   1 
ATOM   2414 C CG   . GLN A 1 172 ? -41.88096 -21.83896 9.15339   1.000 46.11288  ? 172 GLN A CG   1 
ATOM   2415 C CD   . GLN A 1 172 ? -42.86118 -20.80140 9.66841   1.000 61.42024  ? 172 GLN A CD   1 
ATOM   2416 O OE1  . GLN A 1 172 ? -42.72058 -19.60913 9.39901   1.000 90.52772  ? 172 GLN A OE1  1 
ATOM   2417 N NE2  . GLN A 1 172 ? -43.86466 -21.25421 10.41232  1.000 74.37969  ? 172 GLN A NE2  1 
ATOM   2418 H H    . GLN A 1 172 ? -39.14740 -20.12785 6.19383   1.000 101.13771 ? 172 GLN A H    1 
ATOM   2419 H HA   . GLN A 1 172 ? -39.78132 -20.35928 8.21260   1.000 77.27613  ? 172 GLN A HA   1 
ATOM   2420 H HB2  . GLN A 1 172 ? -41.89498 -20.78807 7.40788   1.000 53.93403  ? 172 GLN A HB2  1 
ATOM   2421 H HB3  . GLN A 1 172 ? -41.52466 -22.32021 7.20587   1.000 53.93403  ? 172 GLN A HB3  1 
ATOM   2422 H HG2  . GLN A 1 172 ? -42.33119 -22.69811 9.14549   1.000 55.49400  ? 172 GLN A HG2  1 
ATOM   2423 H HG3  . GLN A 1 172 ? -41.12608 -21.86559 9.76195   1.000 55.49400  ? 172 GLN A HG3  1 
ATOM   2424 H HE21 . GLN A 1 172 ? -43.93162 -22.09544 10.57796  1.000 89.41417  ? 172 GLN A HE21 1 
ATOM   2425 H HE22 . GLN A 1 172 ? -44.44720 -20.70605 10.72818  1.000 89.41417  ? 172 GLN A HE22 1 
HETATM 2426 I I    . IOD B 2 .   ? -50.68713 -31.99732 1.61787   1.000 63.31191  ? 201 IOD A I    1 
HETATM 2427 I I    . IOD C 2 .   ? -19.60613 -38.19882 11.21752  1.000 91.21356  ? 202 IOD A I    1 
HETATM 2428 I I    . IOD D 2 .   ? -16.05067 -27.80057 0.00000   0.50  55.02081  ? 203 IOD A I    1 
HETATM 2429 I I    . IOD E 2 .   ? -20.00156 -33.94235 1.87604   1.000 82.43942  ? 204 IOD A I    1 
HETATM 2430 I I    . IOD F 2 .   ? -28.49022 -45.90773 10.33208  1.000 130.67641 ? 205 IOD A I    1 
HETATM 2431 I I    . IOD G 2 .   ? -39.60026 -24.82701 11.05611  1.000 107.13526 ? 206 IOD A I    1 
HETATM 2432 I I    . IOD H 2 .   ? -30.95763 -42.60379 22.71540  1.000 99.60361  ? 207 IOD A I    1 
HETATM 2433 I I    . IOD I 2 .   ? -24.51014 -24.17497 19.19349  1.000 116.89536 ? 208 IOD A I    1 
HETATM 2434 C C01  . AG7 J 3 .   ? -40.73881 -30.84022 -8.85499  1.000 41.58128  ? 209 AG7 A C01  1 
HETATM 2435 C C02  . AG7 J 3 .   ? -41.19916 -31.74325 -7.73451  1.000 45.64742  ? 209 AG7 A C02  1 
HETATM 2436 O O03  . AG7 J 3 .   ? -39.70204 -30.21006 -8.77589  1.000 23.76878  ? 209 AG7 A O03  1 
HETATM 2437 C C04  . AG7 J 3 .   ? -40.22827 -31.81918 -6.57996  1.000 33.02721  ? 209 AG7 A C04  1 
HETATM 2438 C C05  . AG7 J 3 .   ? -40.75115 -32.76678 -5.47971  1.000 32.59909  ? 209 AG7 A C05  1 
HETATM 2439 C C06  . AG7 J 3 .   ? -41.83171 -32.19091 -4.60606  1.000 36.74928  ? 209 AG7 A C06  1 
HETATM 2440 C C07  . AG7 J 3 .   ? -41.59544 -31.04524 -3.85389  1.000 25.06527  ? 209 AG7 A C07  1 
HETATM 2441 C C08  . AG7 J 3 .   ? -42.57842 -30.50229 -3.04653  1.000 30.75464  ? 209 AG7 A C08  1 
HETATM 2442 C C09  . AG7 J 3 .   ? -43.80815 -31.12596 -2.99532  1.000 32.07310  ? 209 AG7 A C09  1 
HETATM 2443 C C10  . AG7 J 3 .   ? -44.08868 -32.26555 -3.71916  1.000 34.44710  ? 209 AG7 A C10  1 
HETATM 2444 C C11  . AG7 J 3 .   ? -43.08704 -32.79068 -4.52500  1.000 38.90496  ? 209 AG7 A C11  1 
HETATM 2445 N N12  . AG7 J 3 .   ? -37.85077 -31.52005 -6.84403  1.000 46.17256  ? 209 AG7 A N12  1 
HETATM 2446 C C13  . AG7 J 3 .   ? -36.47491 -31.82968 -7.16822  1.000 34.56065  ? 209 AG7 A C13  1 
HETATM 2447 C C14  . AG7 J 3 .   ? -35.82140 -30.74218 -7.98644  1.000 31.26392  ? 209 AG7 A C14  1 
HETATM 2448 C C15  . AG7 J 3 .   ? -36.34076 -30.55565 -9.42239  1.000 39.53903  ? 209 AG7 A C15  1 
HETATM 2449 C C16  . AG7 J 3 .   ? -35.52642 -29.51458 -10.17572 1.000 42.60726  ? 209 AG7 A C16  1 
HETATM 2450 N N17  . AG7 J 3 .   ? -35.37525 -29.95430 -11.43670 1.000 46.30399  ? 209 AG7 A N17  1 
HETATM 2451 O O18  . AG7 J 3 .   ? -35.09680 -28.47527 -9.70091  1.000 25.12155  ? 209 AG7 A O18  1 
HETATM 2452 C C19  . AG7 J 3 .   ? -35.72759 -32.02567 -5.83868  1.000 37.13874  ? 209 AG7 A C19  1 
HETATM 2453 C C20  . AG7 J 3 .   ? -36.26512 -33.19517 -5.02248  1.000 39.32526  ? 209 AG7 A C20  1 
HETATM 2454 C C21  . AG7 J 3 .   ? -36.12245 -34.51255 -5.73179  1.000 51.39977  ? 209 AG7 A C21  1 
HETATM 2455 O O22  . AG7 J 3 .   ? -36.91303 -35.43821 -5.20671  1.000 51.10912  ? 209 AG7 A O22  1 
HETATM 2456 O O23  . AG7 J 3 .   ? -35.37996 -34.72544 -6.66075  1.000 51.21430  ? 209 AG7 A O23  1 
HETATM 2457 C C47  . AG7 J 3 .   ? -38.87700 -32.35742 -7.02835  1.000 40.23566  ? 209 AG7 A C47  1 
HETATM 2458 O O48  . AG7 J 3 .   ? -38.76139 -33.47500 -7.50832  1.000 47.52055  ? 209 AG7 A O48  1 
HETATM 2459 C C50  . AG7 J 3 .   ? -37.71445 -36.22559 -6.10285  1.000 61.22793  ? 209 AG7 A C50  1 
HETATM 2460 C C53  . AG7 J 3 .   ? -39.16382 -36.05165 -5.68866  1.000 65.13714  ? 209 AG7 A C53  1 
HETATM 2461 C C57  . AG7 J 3 .   ? -41.64037 -30.70342 -10.11796 1.000 37.19759  ? 209 AG7 A C57  1 
HETATM 2462 N N58  . AG7 J 3 .   ? -41.90752 -29.27773 -10.05345 1.000 39.28286  ? 209 AG7 A N58  1 
HETATM 2463 C C59  . AG7 J 3 .   ? -43.10790 -28.72076 -9.79292  1.000 31.42714  ? 209 AG7 A C59  1 
HETATM 2464 O O60  . AG7 J 3 .   ? -44.14246 -29.33241 -9.60085  1.000 42.33552  ? 209 AG7 A O60  1 
HETATM 2465 C C78  . AG7 J 3 .   ? -41.00973 -31.26940 -11.37191 1.000 34.63010  ? 209 AG7 A C78  1 
HETATM 2466 C C81  . AG7 J 3 .   ? -41.53988 -30.59561 -12.62335 1.000 35.17116  ? 209 AG7 A C81  1 
HETATM 2467 F F1   . AG7 J 3 .   ? -44.75916 -30.59704 -2.21440  1.000 34.25298  ? 209 AG7 A F1   1 
HETATM 2468 C C82  . AG7 J 3 .   ? -39.47724 -31.19883 -11.34074 1.000 45.63878  ? 209 AG7 A C82  1 
HETATM 2469 C C83  . AG7 J 3 .   ? -35.98840 -31.23456 -11.70704 1.000 61.40998  ? 209 AG7 A C83  1 
HETATM 2470 C C84  . AG7 J 3 .   ? -36.21791 -31.80036 -10.29649 1.000 35.12483  ? 209 AG7 A C84  1 
HETATM 2471 C C1   . AG7 J 3 .   ? -43.11181 -27.22996 -9.72566  1.000 38.94045  ? 209 AG7 A C1   1 
HETATM 2472 C C2   . AG7 J 3 .   ? -44.22539 -26.36229 -9.71836  1.000 34.00832  ? 209 AG7 A C2   1 
HETATM 2473 C C3   . AG7 J 3 .   ? -43.66967 -25.12851 -9.59650  1.000 52.71573  ? 209 AG7 A C3   1 
HETATM 2474 O O4   . AG7 J 3 .   ? -42.33719 -25.26176 -9.50881  1.000 46.22605  ? 209 AG7 A O4   1 
HETATM 2475 N N5   . AG7 J 3 .   ? -41.99906 -26.56670 -9.57326  1.000 42.90644  ? 209 AG7 A N5   1 
HETATM 2476 C C4   . AG7 J 3 .   ? -44.22449 -23.75161 -9.54386  1.000 48.69885  ? 209 AG7 A C4   1 
HETATM 2477 H H2   . AG7 J 3 .   ? -42.06333 -31.43993 -7.41495  1.000 54.93544  ? 209 AG7 A H2   1 
HETATM 2478 H H3   . AG7 J 3 .   ? -41.35787 -32.63303 -8.08666  1.000 54.93544  ? 209 AG7 A H3   1 
HETATM 2479 H H27  . AG7 J 3 .   ? -40.13845 -30.91288 -6.24611  1.000 39.79120  ? 209 AG7 A H27  1 
HETATM 2480 H H28  . AG7 J 3 .   ? -41.08010 -33.57481 -5.90371  1.000 39.27745  ? 209 AG7 A H28  1 
HETATM 2481 H H29  . AG7 J 3 .   ? -40.00131 -33.03441 -4.92562  1.000 39.27745  ? 209 AG7 A H29  1 
HETATM 2482 H H30  . AG7 J 3 .   ? -40.76565 -30.62647 -3.88510  1.000 30.23687  ? 209 AG7 A H30  1 
HETATM 2483 H H31  . AG7 J 3 .   ? -42.41711 -29.73393 -2.54801  1.000 37.06410  ? 209 AG7 A H31  1 
HETATM 2484 H H33  . AG7 J 3 .   ? -44.92448 -32.67027 -3.66878  1.000 41.49506  ? 209 AG7 A H33  1 
HETATM 2485 H H34  . AG7 J 3 .   ? -43.26242 -33.55883 -5.01904  1.000 46.84449  ? 209 AG7 A H34  1 
HETATM 2486 H H49  . AG7 J 3 .   ? -38.01192 -30.74375 -6.51088  1.000 55.56561  ? 209 AG7 A H49  1 
HETATM 2487 H H91  . AG7 J 3 .   ? -36.46161 -32.62810 -7.71891  1.000 41.63132  ? 209 AG7 A H91  1 
HETATM 2488 H H35  . AG7 J 3 .   ? -35.91394 -29.90721 -7.50150  1.000 37.67525  ? 209 AG7 A H35  1 
HETATM 2489 H H36  . AG7 J 3 .   ? -34.86802 -30.91926 -8.01125  1.000 37.67525  ? 209 AG7 A H36  1 
HETATM 2490 H H94  . AG7 J 3 .   ? -37.27774 -30.30815 -9.38106  1.000 47.60538  ? 209 AG7 A H94  1 
HETATM 2491 H H39  . AG7 J 3 .   ? -34.94674 -29.50614 -12.03263 1.000 55.72333  ? 209 AG7 A H39  1 
HETATM 2492 H H191 . AG7 J 3 .   ? -35.79022 -31.20593 -5.32390  1.000 44.72503  ? 209 AG7 A H191 1 
HETATM 2493 H H192 . AG7 J 3 .   ? -34.78592 -32.15962 -6.02899  1.000 44.72503  ? 209 AG7 A H192 1 
HETATM 2494 H H41  . AG7 J 3 .   ? -37.20347 -33.07587 -4.80759  1.000 47.34886  ? 209 AG7 A H41  1 
HETATM 2495 H H42  . AG7 J 3 .   ? -35.81164 -33.26938 -4.16823  1.000 47.34886  ? 209 AG7 A H42  1 
HETATM 2496 H H51  . AG7 J 3 .   ? -37.44621 -37.15626 -6.04998  1.000 73.63205  ? 209 AG7 A H51  1 
HETATM 2497 H H52  . AG7 J 3 .   ? -37.57452 -35.92719 -7.01514  1.000 73.63205  ? 209 AG7 A H52  1 
HETATM 2498 H H53  . AG7 J 3 .   ? -39.33712 -36.44736 -4.82016  1.000 78.32311  ? 209 AG7 A H53  1 
HETATM 2499 H H54  . AG7 J 3 .   ? -39.40924 -35.11491 -5.63209  1.000 78.32311  ? 209 AG7 A H54  1 
HETATM 2500 H H56  . AG7 J 3 .   ? -39.76877 -36.46981 -6.32117  1.000 78.32311  ? 209 AG7 A H56  1 
HETATM 2501 H H77  . AG7 J 3 .   ? -42.50392 -31.14125 -10.05905 1.000 44.79565  ? 209 AG7 A H77  1 
HETATM 2502 H H61  . AG7 J 3 .   ? -41.24360 -28.74930 -10.19336 1.000 47.29797  ? 209 AG7 A H61  1 
HETATM 2503 H H79  . AG7 J 3 .   ? -41.27135 -32.20302 -11.40054 1.000 41.71466  ? 209 AG7 A H79  1 
HETATM 2504 H H82  . AG7 J 3 .   ? -41.30113 -31.10496 -13.41358 1.000 42.36393  ? 209 AG7 A H82  1 
HETATM 2505 H H84  . AG7 J 3 .   ? -41.17078 -29.70318 -12.71406 1.000 42.36393  ? 209 AG7 A H84  1 
HETATM 2506 H H85  . AG7 J 3 .   ? -42.50653 -30.52265 -12.58942 1.000 42.36393  ? 209 AG7 A H85  1 
HETATM 2507 H H86  . AG7 J 3 .   ? -39.09449 -31.78388 -10.66835 1.000 54.92508  ? 209 AG7 A H86  1 
HETATM 2508 H H87  . AG7 J 3 .   ? -39.15287 -30.30600 -11.14442 1.000 54.92508  ? 209 AG7 A H87  1 
HETATM 2509 H H88  . AG7 J 3 .   ? -39.07872 -31.45568 -12.18698 1.000 54.92508  ? 209 AG7 A H88  1 
HETATM 2510 H H89  . AG7 J 3 .   ? -35.40033 -31.79394 -12.23823 1.000 73.85052  ? 209 AG7 A H89  1 
HETATM 2511 H H90  . AG7 J 3 .   ? -36.81650 -31.12380 -12.19986 1.000 73.85052  ? 209 AG7 A H90  1 
HETATM 2512 H H92  . AG7 J 3 .   ? -37.02328 -32.34010 -10.26544 1.000 42.30834  ? 209 AG7 A H92  1 
HETATM 2513 H H93  . AG7 J 3 .   ? -35.47427 -32.35891 -10.02095 1.000 42.30834  ? 209 AG7 A H93  1 
HETATM 2514 H H8   . AG7 J 3 .   ? -45.12751 -26.57922 -9.78172  1.000 40.96853  ? 209 AG7 A H8   1 
HETATM 2515 H H5   . AG7 J 3 .   ? -44.22613 -23.40872 -8.63649  1.000 58.59716  ? 209 AG7 A H5   1 
HETATM 2516 H H6   . AG7 J 3 .   ? -43.70223 -23.14210 -10.08850 1.000 58.59716  ? 209 AG7 A H6   1 
HETATM 2517 H H7   . AG7 J 3 .   ? -45.13798 -23.72901 -9.86931  1.000 58.59716  ? 209 AG7 A H7   1 
HETATM 2518 O O    . HOH K 4 .   ? -26.14516 -31.75209 -6.55989  1.000 39.62199  ? 301 HOH A O    1 
HETATM 2519 O O    . HOH K 4 .   ? -48.89758 -24.44802 -7.22034  1.000 34.53727  ? 302 HOH A O    1 
HETATM 2520 O O    . HOH K 4 .   ? -44.83425 -11.96405 -1.37334  1.000 42.61419  ? 303 HOH A O    1 
HETATM 2521 O O    . HOH K 4 .   ? -43.19064 -23.09420 5.52413   1.000 41.08041  ? 304 HOH A O    1 
HETATM 2522 O O    . HOH K 4 .   ? -37.45490 -38.04962 2.93351   1.000 39.70678  ? 305 HOH A O    1 
HETATM 2523 O O    . HOH K 4 .   ? -35.36972 -33.50962 -14.83092 1.000 65.77531  ? 306 HOH A O    1 
HETATM 2524 O O    . HOH K 4 .   ? -26.63138 -17.47111 -11.98492 1.000 44.48800  ? 307 HOH A O    1 
HETATM 2525 O O    . HOH K 4 .   ? -38.85279 -13.29197 -9.15339  1.000 40.31182  ? 308 HOH A O    1 
HETATM 2526 O O    . HOH K 4 .   ? -42.59870 -25.75232 2.94740   1.000 31.81287  ? 309 HOH A O    1 
HETATM 2527 O O    . HOH K 4 .   ? -22.75815 -36.65540 4.89529   1.000 47.97714  ? 310 HOH A O    1 
HETATM 2528 O O    . HOH K 4 .   ? -34.38657 -24.61364 -12.85303 1.000 40.57725  ? 311 HOH A O    1 
HETATM 2529 O O    . HOH K 4 .   ? -34.09108 -31.56250 -14.77705 1.000 50.69833  ? 312 HOH A O    1 
HETATM 2530 O O    . HOH K 4 .   ? -43.28324 -18.22094 2.87478   1.000 43.95292  ? 313 HOH A O    1 
HETATM 2531 O O    . HOH K 4 .   ? -16.42808 -25.04772 -8.85761  1.000 52.57959  ? 314 HOH A O    1 
HETATM 2532 O O    . HOH K 4 .   ? -24.61537 -13.53185 -1.79669  1.000 40.24910  ? 315 HOH A O    1 
HETATM 2533 O O    . HOH K 4 .   ? -18.10521 -31.35915 0.00000   0.50  40.55340  ? 316 HOH A O    1 
HETATM 2534 O O    . HOH K 4 .   ? -22.79863 -14.46361 -3.74604  1.000 46.22707  ? 317 HOH A O    1 
HETATM 2535 O O    . HOH K 4 .   ? -35.48346 -51.39923 11.99472  1.000 52.38059  ? 318 HOH A O    1 
HETATM 2536 O O    . HOH K 4 .   ? -26.55680 -39.42300 4.09211   1.000 32.86007  ? 319 HOH A O    1 
HETATM 2537 O O    . HOH K 4 .   ? -25.54707 -40.04040 2.11729   1.000 38.28382  ? 320 HOH A O    1 
HETATM 2538 O O    . HOH K 4 .   ? -23.25025 -15.60292 -1.43627  1.000 44.00494  ? 321 HOH A O    1 
HETATM 2539 O O    . HOH K 4 .   ? -21.26313 -17.26720 -2.57982  1.000 52.18234  ? 322 HOH A O    1 
HETATM 2540 O O    . HOH K 4 .   ? -22.08160 -22.54107 20.09386  1.000 50.89344  ? 323 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . SER A 4   ? 0.25683 0.51656 0.62804 -0.07187 0.01147  0.03396  4   SER A N   
2    C CA  . SER A 4   ? 0.46045 0.70918 0.81225 -0.06802 -0.00737 0.01687  4   SER A CA  
3    C C   . SER A 4   ? 0.63331 0.84317 0.93646 -0.06028 -0.00624 0.00318  4   SER A C   
4    O O   . SER A 4   ? 0.48467 0.68950 0.76055 -0.04745 -0.00787 -0.00369 4   SER A O   
5    C CB  . SER A 4   ? 0.33695 0.58833 0.71468 -0.08643 -0.03137 0.00979  4   SER A CB  
6    O OG  . SER A 4   ? 0.41947 0.66330 0.77307 -0.08144 -0.04943 -0.00680 4   SER A OG  
11   N N   . ILE A 5   ? 0.35144 0.53495 0.64672 -0.06835 -0.00382 0.00106  5   ILE A N   
12   C CA  . ILE A 5   ? 0.43570 0.58793 0.68942 -0.05968 0.00059  -0.00902 5   ILE A CA  
13   C C   . ILE A 5   ? 0.47445 0.63082 0.70759 -0.04381 0.01781  -0.00272 5   ILE A C   
14   O O   . ILE A 5   ? 0.35699 0.49646 0.55776 -0.03444 0.01886  -0.01070 5   ILE A O   
15   C CB  . ILE A 5   ? 0.35361 0.47997 0.60816 -0.06887 0.00206  -0.00874 5   ILE A CB  
16   C CG1 . ILE A 5   ? 0.47585 0.57348 0.69126 -0.05963 0.00378  -0.02096 5   ILE A CG1 
17   C CG2 . ILE A 5   ? 0.40555 0.54310 0.67702 -0.07111 0.01937  0.01172  5   ILE A CG2 
18   C CD1 . ILE A 5   ? 0.60929 0.68149 0.82452 -0.06447 0.00669  -0.01894 5   ILE A CD1 
30   N N   . TRP A 6   ? 0.30425 0.48411 0.55664 -0.04048 0.03126  0.01123  6   TRP A N   
31   C CA  . TRP A 6   ? 0.45777 0.64106 0.69104 -0.02375 0.04568  0.01357  6   TRP A CA  
32   C C   . TRP A 6   ? 0.43791 0.62570 0.66298 -0.01238 0.03850  0.00723  6   TRP A C   
33   O O   . TRP A 6   ? 0.39869 0.57362 0.59904 0.00016  0.04401  0.00360  6   TRP A O   
34   C CB  . TRP A 6   ? 0.38548 0.59777 0.64117 -0.02050 0.06202  0.02822  6   TRP A CB  
35   C CG  . TRP A 6   ? 0.39884 0.60590 0.65481 -0.02850 0.07250  0.03867  6   TRP A CG  
36   C CD1 . TRP A 6   ? 0.31673 0.53679 0.60505 -0.04437 0.07272  0.05258  6   TRP A CD1 
37   C CD2 . TRP A 6   ? 0.23918 0.42678 0.46286 -0.02165 0.08275  0.03814  6   TRP A CD2 
38   N NE1 . TRP A 6   ? 0.30826 0.51749 0.58520 -0.04698 0.08338  0.06263  6   TRP A NE1 
39   C CE2 . TRP A 6   ? 0.42107 0.61155 0.65733 -0.03257 0.08933  0.05328  6   TRP A CE2 
40   C CE3 . TRP A 6   ? 0.35924 0.52767 0.54657 -0.00832 0.08548  0.02743  6   TRP A CE3 
41   C CZ2 . TRP A 6   ? 0.53104 0.70756 0.74195 -0.02887 0.09846  0.05806  6   TRP A CZ2 
42   C CZ3 . TRP A 6   ? 0.38635 0.54160 0.55029 -0.00573 0.09367  0.03015  6   TRP A CZ3 
43   C CH2 . TRP A 6   ? 0.30975 0.46988 0.48410 -0.01510 0.10007  0.04535  6   TRP A CH2 
54   N N   . SER A 7   ? 0.37599 0.58116 0.62249 -0.01712 0.02460  0.00673  7   SER A N   
55   C CA  . SER A 7   ? 0.25597 0.46596 0.49527 -0.00637 0.01594  0.00386  7   SER A CA  
56   C C   . SER A 7   ? 0.26838 0.45039 0.47054 -0.00449 0.00898  -0.00542 7   SER A C   
57   O O   . SER A 7   ? 0.25954 0.43946 0.44949 0.00567  0.00520  -0.00454 7   SER A O   
58   C CB  . SER A 7   ? 0.45100 0.68769 0.72027 -0.01304 -0.00023 0.00577  7   SER A CB  
59   O OG  . SER A 7   ? 0.44872 0.67262 0.70677 -0.02484 -0.01723 -0.00468 7   SER A OG  
65   N N   . ARG A 8   ? 0.37889 0.54079 0.56515 -0.01358 0.00741  -0.01279 8   ARG A N   
66   C CA  . ARG A 8   ? 0.30791 0.44896 0.46114 -0.01167 0.00301  -0.02092 8   ARG A CA  
67   C C   . ARG A 8   ? 0.35193 0.47542 0.48338 -0.00342 0.01551  -0.01900 8   ARG A C   
68   O O   . ARG A 8   ? 0.28388 0.39378 0.39128 -0.00184 0.01354  -0.02279 8   ARG A O   
69   C CB  . ARG A 8   ? 0.33388 0.46209 0.48171 -0.02221 -0.00377 -0.03151 8   ARG A CB  
70   C CG  . ARG A 8   ? 0.29626 0.43752 0.46343 -0.03182 -0.02053 -0.03746 8   ARG A CG  
71   C CD  . ARG A 8   ? 0.35722 0.48054 0.52577 -0.04217 -0.02687 -0.04910 8   ARG A CD  
72   N NE  . ARG A 8   ? 0.48982 0.59928 0.62665 -0.03823 -0.03371 -0.06420 8   ARG A NE  
73   C CZ  . ARG A 8   ? 0.41023 0.51524 0.54368 -0.04335 -0.04968 -0.08057 8   ARG A CZ  
74   N NH1 . ARG A 8   ? 0.36112 0.47064 0.52374 -0.05538 -0.06313 -0.08428 8   ARG A NH1 
75   N NH2 . ARG A 8   ? 0.38715 0.48406 0.48784 -0.03620 -0.05246 -0.09410 8   ARG A NH2 
89   N N   . ILE A 9   ? 0.31287 0.43884 0.45233 0.00184  0.02783  -0.01339 9   ILE A N   
90   C CA  . ILE A 9   ? 0.29417 0.40382 0.41376 0.00972  0.03735  -0.01363 9   ILE A CA  
91   C C   . ILE A 9   ? 0.34507 0.45933 0.46829 0.02233  0.03832  -0.01059 9   ILE A C   
92   O O   . ILE A 9   ? 0.21991 0.35369 0.36449 0.02801  0.04221  -0.00668 9   ILE A O   
93   C CB  . ILE A 9   ? 0.34364 0.45174 0.46430 0.00851  0.04951  -0.01139 9   ILE A CB  
94   C CG1 . ILE A 9   ? 0.34951 0.44963 0.47070 -0.00320 0.04680  -0.01294 9   ILE A CG1 
95   C CG2 . ILE A 9   ? 0.40827 0.50039 0.50651 0.01679  0.05635  -0.01396 9   ILE A CG2 
96   C CD1 . ILE A 9   ? 0.40915 0.51438 0.54124 -0.00703 0.05666  -0.00498 9   ILE A CD1 
108  N N   . VAL A 10  ? 0.30015 0.39717 0.40552 0.02699  0.03465  -0.01152 10  VAL A N   
109  C CA  . VAL A 10  ? 0.47502 0.57012 0.58512 0.03897  0.03201  -0.00833 10  VAL A CA  
110  C C   . VAL A 10  ? 0.39250 0.46148 0.48428 0.04378  0.03400  -0.01122 10  VAL A C   
111  O O   . VAL A 10  ? 0.39770 0.45306 0.47271 0.03586  0.03269  -0.01232 10  VAL A O   
112  C CB  . VAL A 10  ? 0.22966 0.33234 0.34394 0.03816  0.01878  -0.00195 10  VAL A CB  
113  C CG1 . VAL A 10  ? 0.50702 0.63341 0.63644 0.03024  0.01295  -0.00205 10  VAL A CG1 
114  C CG2 . VAL A 10  ? 0.37359 0.46023 0.46511 0.03232  0.01325  0.00025  10  VAL A CG2 
124  N N   . ASN A 11  ? 0.37148 0.43421 0.46868 0.05725  0.03619  -0.01319 11  ASN A N   
125  C CA  . ASN A 11  ? 0.48333 0.51783 0.56658 0.06221  0.03456  -0.01777 11  ASN A CA  
126  C C   . ASN A 11  ? 0.36669 0.38598 0.44209 0.05368  0.02392  -0.00964 11  ASN A C   
127  O O   . ASN A 11  ? 0.41195 0.43692 0.49559 0.05459  0.01593  0.00018  11  ASN A O   
128  C CB  . ASN A 11  ? 0.34587 0.37514 0.43991 0.08051  0.03525  -0.02202 11  ASN A CB  
129  C CG  . ASN A 11  ? 0.52952 0.53642 0.60862 0.08859  0.03918  -0.03527 11  ASN A CG  
130  O OD1 . ASN A 11  ? 0.89811 0.91666 0.97183 0.09446  0.05039  -0.04346 11  ASN A OD1 
131  N ND2 . ASN A 11  ? 0.85844 0.83384 0.93083 0.08858  0.02909  -0.03684 11  ASN A ND2 
138  N N   . PHE A 12  ? 0.47000 0.47345 0.53023 0.04540  0.02386  -0.01199 12  PHE A N   
139  C CA  . PHE A 12  ? 0.49531 0.48911 0.54936 0.03579  0.01627  -0.00219 12  PHE A CA  
140  C C   . PHE A 12  ? 0.45859 0.42647 0.50612 0.03388  0.01360  -0.00648 12  PHE A C   
141  O O   . PHE A 12  ? 0.39577 0.36224 0.43385 0.03006  0.01813  -0.01489 12  PHE A O   
142  C CB  . PHE A 12  ? 0.54612 0.55707 0.59183 0.02451  0.01878  0.00024  12  PHE A CB  
143  C CG  . PHE A 12  ? 0.36991 0.38374 0.41047 0.01712  0.01300  0.01301  12  PHE A CG  
144  C CD1 . PHE A 12  ? 0.27458 0.29932 0.31861 0.01938  0.00666  0.02346  12  PHE A CD1 
145  C CD2 . PHE A 12  ? 0.34348 0.35349 0.37616 0.00824  0.01414  0.01612  12  PHE A CD2 
146  C CE1 . PHE A 12  ? 0.35484 0.38633 0.39097 0.01322  0.00256  0.03755  12  PHE A CE1 
147  C CE2 . PHE A 12  ? 0.49398 0.51265 0.52249 0.00176  0.01120  0.03033  12  PHE A CE2 
148  C CZ  . PHE A 12  ? 0.32646 0.35585 0.35483 0.00437  0.00594  0.04141  12  PHE A CZ  
158  N N   . GLY A 13  ? 0.44697 0.39352 0.50095 0.03623  0.00456  -0.00032 13  GLY A N   
159  C CA  . GLY A 13  ? 0.48063 0.39934 0.53178 0.03294  -0.00133 -0.00559 13  GLY A CA  
160  C C   . GLY A 13  ? 0.48540 0.39680 0.52772 0.04205  0.00348  -0.02577 13  GLY A C   
161  O O   . GLY A 13  ? 0.50280 0.41872 0.54726 0.05687  0.00874  -0.03467 13  GLY A O   
165  N N   . SER A 14  ? 0.38877 0.29253 0.42103 0.03383  0.00187  -0.03234 14  SER A N   
166  C CA  . SER A 14  ? 0.47191 0.37141 0.49033 0.04172  0.00553  -0.05068 14  SER A CA  
167  C C   . SER A 14  ? 0.47783 0.40595 0.48762 0.04195  0.01844  -0.05176 14  SER A C   
168  O O   . SER A 14  ? 0.37003 0.29996 0.36584 0.04732  0.02271  -0.06316 14  SER A O   
169  C CB  . SER A 14  ? 0.40992 0.28900 0.42210 0.03235  -0.00509 -0.05687 14  SER A CB  
170  O OG  . SER A 14  ? 0.54990 0.44203 0.56609 0.01570  -0.00604 -0.04353 14  SER A OG  
176  N N   . GLY A 15  ? 0.32314 0.27258 0.34040 0.03636  0.02363  -0.04006 15  GLY A N   
177  C CA  . GLY A 15  ? 0.48191 0.45381 0.49539 0.03513  0.03374  -0.03992 15  GLY A CA  
178  C C   . GLY A 15  ? 0.40521 0.39658 0.43142 0.03637  0.03807  -0.03284 15  GLY A C   
179  O O   . GLY A 15  ? 0.36124 0.35535 0.39721 0.04607  0.03863  -0.03324 15  GLY A O   
183  N N   . TRP A 16  ? 0.41498 0.42013 0.44253 0.02741  0.03989  -0.02746 16  TRP A N   
184  C CA  . TRP A 16  ? 0.27160 0.29515 0.31098 0.02678  0.04175  -0.02333 16  TRP A CA  
185  C C   . TRP A 16  ? 0.42411 0.45337 0.46145 0.01750  0.03737  -0.01895 16  TRP A C   
186  O O   . TRP A 16  ? 0.39041 0.41350 0.41876 0.01218  0.03587  -0.01806 16  TRP A O   
187  C CB  . TRP A 16  ? 0.26896 0.30583 0.31277 0.02790  0.05067  -0.02529 16  TRP A CB  
188  C CG  . TRP A 16  ? 0.35134 0.38891 0.39361 0.03916  0.05765  -0.02976 16  TRP A CG  
189  C CD1 . TRP A 16  ? 0.23873 0.26647 0.26460 0.04326  0.06087  -0.03604 16  TRP A CD1 
190  C CD2 . TRP A 16  ? 0.44219 0.49396 0.49889 0.04946  0.06216  -0.02939 16  TRP A CD2 
191  N NE1 . TRP A 16  ? 0.33636 0.37068 0.36201 0.05647  0.06798  -0.04110 16  TRP A NE1 
192  C CE2 . TRP A 16  ? 0.41079 0.46085 0.45704 0.06096  0.06985  -0.03664 16  TRP A CE2 
193  C CE3 . TRP A 16  ? 0.22967 0.29818 0.30752 0.05096  0.05995  -0.02395 16  TRP A CE3 
194  C CZ2 . TRP A 16  ? 0.24597 0.31167 0.30276 0.07531  0.07758  -0.03884 16  TRP A CZ2 
195  C CZ3 . TRP A 16  ? 0.35497 0.43947 0.44703 0.06390  0.06641  -0.02445 16  TRP A CZ3 
196  C CH2 . TRP A 16  ? 0.37587 0.45946 0.45768 0.07665  0.07624  -0.03195 16  TRP A CH2 
207  N N   . GLY A 17  ? 0.54314 0.58689 0.58936 0.01632  0.03491  -0.01690 17  GLY A N   
208  C CA  . GLY A 17  ? 0.35878 0.41030 0.40001 0.00982  0.03084  -0.01663 17  GLY A CA  
209  C C   . GLY A 17  ? 0.30187 0.36714 0.35458 0.00760  0.02870  -0.01995 17  GLY A C   
210  O O   . GLY A 17  ? 0.32254 0.39533 0.39055 0.01037  0.03033  -0.01880 17  GLY A O   
214  N N   . PHE A 18  ? 0.32343 0.39330 0.36999 0.00280  0.02456  -0.02470 18  PHE A N   
215  C CA  . PHE A 18  ? 0.36364 0.44123 0.42161 -0.00168 0.02016  -0.03092 18  PHE A CA  
216  C C   . PHE A 18  ? 0.34600 0.43316 0.39492 -0.00307 0.00992  -0.03601 18  PHE A C   
217  O O   . PHE A 18  ? 0.25000 0.33625 0.28021 -0.00175 0.01029  -0.03846 18  PHE A O   
218  C CB  . PHE A 18  ? 0.26425 0.33135 0.32353 -0.00536 0.02517  -0.03626 18  PHE A CB  
219  C CG  . PHE A 18  ? 0.39827 0.46718 0.47207 -0.01179 0.01900  -0.04256 18  PHE A CG  
220  C CD1 . PHE A 18  ? 0.29406 0.37024 0.39132 -0.01610 0.01988  -0.03705 18  PHE A CD1 
221  C CD2 . PHE A 18  ? 0.28631 0.34997 0.35184 -0.01344 0.01220  -0.05434 18  PHE A CD2 
222  C CE1 . PHE A 18  ? 0.29110 0.36752 0.40658 -0.02486 0.01237  -0.04129 18  PHE A CE1 
223  C CE2 . PHE A 18  ? 0.44689 0.50693 0.52742 -0.02016 0.00376  -0.06225 18  PHE A CE2 
224  C CZ  . PHE A 18  ? 0.34026 0.40570 0.44746 -0.02736 0.00301  -0.05478 18  PHE A CZ  
234  N N   . TRP A 19  ? 0.36220 0.46197 0.42444 -0.00532 0.00068  -0.03739 19  TRP A N   
235  C CA  . TRP A 19  ? 0.43676 0.54754 0.48862 -0.00653 -0.01175 -0.04457 19  TRP A CA  
236  C C   . TRP A 19  ? 0.39050 0.49337 0.44241 -0.01177 -0.01594 -0.06046 19  TRP A C   
237  O O   . TRP A 19  ? 0.38154 0.48399 0.45570 -0.01866 -0.02150 -0.06443 19  TRP A O   
238  C CB  . TRP A 19  ? 0.27129 0.40014 0.33934 -0.00688 -0.02285 -0.03977 19  TRP A CB  
239  C CG  . TRP A 19  ? 0.41366 0.54875 0.48024 0.00064  -0.02209 -0.02504 19  TRP A CG  
240  C CD1 . TRP A 19  ? 0.29812 0.43378 0.38414 0.00557  -0.01676 -0.01554 19  TRP A CD1 
241  C CD2 . TRP A 19  ? 0.37148 0.51222 0.41659 0.00506  -0.02699 -0.01742 19  TRP A CD2 
242  N NE1 . TRP A 19  ? 0.26598 0.40261 0.34574 0.01307  -0.01961 -0.00384 19  TRP A NE1 
243  C CE2 . TRP A 19  ? 0.40194 0.54196 0.45738 0.01169  -0.02595 -0.00259 19  TRP A CE2 
244  C CE3 . TRP A 19  ? 0.32374 0.47131 0.34153 0.00494  -0.03160 -0.02101 19  TRP A CE3 
245  C CZ2 . TRP A 19  ? 0.37869 0.52154 0.42068 0.01623  -0.03065 0.01140  19  TRP A CZ2 
246  C CZ3 . TRP A 19  ? 0.42091 0.57674 0.42307 0.00940  -0.03436 -0.00601 19  TRP A CZ3 
247  C CH2 . TRP A 19  ? 0.39709 0.54905 0.41264 0.01401  -0.03451 0.01133  19  TRP A CH2 
258  N N   . VAL A 20  ? 0.38488 0.48159 0.41440 -0.00829 -0.01339 -0.06913 20  VAL A N   
259  C CA  . VAL A 20  ? 0.34391 0.43074 0.37176 -0.01023 -0.01948 -0.08739 20  VAL A CA  
260  C C   . VAL A 20  ? 0.38267 0.48072 0.40797 -0.01278 -0.03680 -0.09933 20  VAL A C   
261  O O   . VAL A 20  ? 0.34257 0.43089 0.38085 -0.01882 -0.04734 -0.11336 20  VAL A O   
262  C CB  . VAL A 20  ? 0.47561 0.55763 0.48043 -0.00247 -0.01172 -0.09476 20  VAL A CB  
263  C CG1 . VAL A 20  ? 0.39843 0.46472 0.40447 -0.00173 -0.01752 -0.11526 20  VAL A CG1 
264  C CG2 . VAL A 20  ? 0.31986 0.39514 0.32742 -0.00069 0.00283  -0.08134 20  VAL A CG2 
274  N N   . SER A 21  ? 0.39882 0.51670 0.40852 -0.00889 -0.04171 -0.09317 21  SER A N   
275  C CA  . SER A 21  ? 0.45316 0.58626 0.45590 -0.01017 -0.05992 -0.10322 21  SER A CA  
276  C C   . SER A 21  ? 0.40276 0.55666 0.40754 -0.00833 -0.06369 -0.08447 21  SER A C   
277  O O   . SER A 21  ? 0.46850 0.62047 0.48172 -0.00601 -0.05212 -0.06633 21  SER A O   
278  C CB  . SER A 21  ? 0.37053 0.50832 0.33698 -0.00238 -0.06336 -0.12039 21  SER A CB  
279  O OG  . SER A 21  ? 0.53850 0.69659 0.47897 0.00494  -0.05847 -0.10646 21  SER A OG  
285  N N   . PRO A 22  ? 0.41479 0.58771 0.41211 -0.00841 -0.08109 -0.08869 22  PRO A N   
286  C CA  . PRO A 22  ? 0.45057 0.64347 0.44781 -0.00427 -0.08540 -0.06858 22  PRO A CA  
287  C C   . PRO A 22  ? 0.38491 0.58112 0.35441 0.00385  -0.07411 -0.05311 22  PRO A C   
288  O O   . PRO A 22  ? 0.44663 0.64954 0.42250 0.00729  -0.07341 -0.03206 22  PRO A O   
289  C CB  . PRO A 22  ? 0.48307 0.69671 0.47222 -0.00580 -0.10865 -0.07936 22  PRO A CB  
290  C CG  . PRO A 22  ? 0.35117 0.55192 0.35391 -0.01466 -0.11766 -0.10381 22  PRO A CG  
291  C CD  . PRO A 22  ? 0.55810 0.73382 0.55121 -0.01276 -0.10022 -0.11200 22  PRO A CD  
299  N N   . SER A 23  ? 0.58416 0.77643 0.52606 0.00716  -0.06544 -0.06201 23  SER A N   
300  C CA  . SER A 23  ? 0.38208 0.58291 0.29929 0.01298  -0.05476 -0.04588 23  SER A CA  
301  C C   . SER A 23  ? 0.43536 0.61950 0.35653 0.01275  -0.03590 -0.04200 23  SER A C   
302  O O   . SER A 23  ? 0.43770 0.62704 0.34937 0.01458  -0.02684 -0.02347 23  SER A O   
303  C CB  . SER A 23  ? 0.35729 0.57928 0.23507 0.01909  -0.05958 -0.05654 23  SER A CB  
304  O OG  . SER A 23  ? 0.69574 0.94025 0.56077 0.02108  -0.07580 -0.04937 23  SER A OG  
310  N N   . LEU A 24  ? 0.47178 0.63702 0.40784 0.00986  -0.03097 -0.05716 24  LEU A N   
311  C CA  . LEU A 24  ? 0.30784 0.45958 0.24678 0.01030  -0.01527 -0.05518 24  LEU A CA  
312  C C   . LEU A 24  ? 0.27060 0.40432 0.23742 0.00579  -0.01010 -0.04557 24  LEU A C   
313  O O   . LEU A 24  ? 0.33338 0.45926 0.32054 0.00202  -0.01507 -0.05180 24  LEU A O   
314  C CB  . LEU A 24  ? 0.47790 0.62110 0.41142 0.01268  -0.01339 -0.07815 24  LEU A CB  
315  C CG  . LEU A 24  ? 0.60521 0.74234 0.53702 0.01593  0.00178  -0.07657 24  LEU A CG  
316  C CD1 . LEU A 24  ? 0.53864 0.69853 0.44941 0.02039  0.01001  -0.06306 24  LEU A CD1 
317  C CD2 . LEU A 24  ? 0.43392 0.56000 0.36404 0.02055  0.00168  -0.09989 24  LEU A CD2 
329  N N   . PHE A 25  ? 0.44852 0.57725 0.41627 0.00605  -0.00030 -0.03061 25  PHE A N   
330  C CA  . PHE A 25  ? 0.23230 0.34443 0.22032 0.00399  0.00472  -0.02287 25  PHE A CA  
331  C C   . PHE A 25  ? 0.34414 0.44674 0.32992 0.00323  0.01560  -0.02108 25  PHE A C   
332  O O   . PHE A 25  ? 0.45051 0.56141 0.42499 0.00335  0.01943  -0.01207 25  PHE A O   
333  C CB  . PHE A 25  ? 0.31869 0.43245 0.31246 0.00559  0.00056  -0.00584 25  PHE A CB  
334  C CG  . PHE A 25  ? 0.41685 0.51435 0.42989 0.00657  0.00425  -0.00199 25  PHE A CG  
335  C CD1 . PHE A 25  ? 0.40963 0.50781 0.44089 0.00777  0.00202  -0.00741 25  PHE A CD1 
336  C CD2 . PHE A 25  ? 0.30761 0.39113 0.32101 0.00650  0.00956  0.00672  25  PHE A CD2 
337  C CE1 . PHE A 25  ? 0.35505 0.44244 0.40085 0.01130  0.00724  -0.00498 25  PHE A CE1 
338  C CE2 . PHE A 25  ? 0.42997 0.49807 0.45689 0.00952  0.01213  0.00659  25  PHE A CE2 
339  C CZ  . PHE A 25  ? 0.38467 0.45587 0.42600 0.01319  0.01200  0.00044  25  PHE A CZ  
349  N N   . ILE A 26  ? 0.33877 0.42699 0.33644 0.00198  0.02020  -0.02771 26  ILE A N   
350  C CA  . ILE A 26  ? 0.33175 0.41275 0.32833 0.00157  0.02830  -0.02729 26  ILE A CA  
351  C C   . ILE A 26  ? 0.25459 0.32089 0.26207 0.00041  0.03095  -0.02151 26  ILE A C   
352  O O   . ILE A 26  ? 0.42321 0.48438 0.44077 0.00126  0.02955  -0.02256 26  ILE A O   
353  C CB  . ILE A 26  ? 0.25535 0.33278 0.25210 0.00309  0.03059  -0.04106 26  ILE A CB  
354  C CG1 . ILE A 26  ? 0.37437 0.43949 0.38609 0.00083  0.02868  -0.04612 26  ILE A CG1 
355  C CG2 . ILE A 26  ? 0.32787 0.41800 0.31118 0.00666  0.02698  -0.05164 26  ILE A CG2 
356  C CD1 . ILE A 26  ? 0.28919 0.34545 0.30454 0.00170  0.02923  -0.05703 26  ILE A CD1 
368  N N   . THR A 27  ? 0.30645 0.36837 0.31219 -0.00115 0.03457  -0.01605 27  THR A N   
369  C CA  . THR A 27  ? 0.35797 0.40497 0.36973 -0.00153 0.03515  -0.01335 27  THR A CA  
370  C C   . THR A 27  ? 0.35098 0.39604 0.36155 -0.00435 0.03771  -0.01232 27  THR A C   
371  O O   . THR A 27  ? 0.39221 0.44908 0.40016 -0.00478 0.04056  -0.01322 27  THR A O   
372  C CB  . THR A 27  ? 0.36171 0.40235 0.37646 -0.00113 0.03032  -0.00433 27  THR A CB  
373  O OG1 . THR A 27  ? 0.38185 0.40543 0.40035 0.00046  0.02997  -0.00634 27  THR A OG1 
374  C CG2 . THR A 27  ? 0.38572 0.43346 0.39682 -0.00580 0.02833  0.00792  27  THR A CG2 
382  N N   . SER A 28  ? 0.49046 0.52191 0.50341 -0.00514 0.03596  -0.01166 28  SER A N   
383  C CA  . SER A 28  ? 0.32645 0.35629 0.34051 -0.00905 0.03502  -0.01025 28  SER A CA  
384  C C   . SER A 28  ? 0.51554 0.54551 0.53475 -0.01589 0.03040  0.00069  28  SER A C   
385  O O   . SER A 28  ? 0.43160 0.45088 0.45283 -0.01622 0.02597  0.00555  28  SER A O   
386  C CB  . SER A 28  ? 0.37730 0.39267 0.38864 -0.00656 0.03334  -0.01684 28  SER A CB  
387  O OG  . SER A 28  ? 0.48572 0.49911 0.49851 -0.01123 0.02881  -0.01588 28  SER A OG  
393  N N   . THR A 29  ? 0.31287 0.35600 0.33722 -0.02133 0.03124  0.00623  29  THR A N   
394  C CA  . THR A 29  ? 0.35416 0.40096 0.38806 -0.03063 0.02721  0.02047  29  THR A CA  
395  C C   . THR A 29  ? 0.44291 0.46392 0.48312 -0.03562 0.01680  0.01991  29  THR A C   
396  O O   . THR A 29  ? 0.34619 0.35946 0.39570 -0.04308 0.01076  0.03197  29  THR A O   
397  C CB  . THR A 29  ? 0.36048 0.43233 0.40280 -0.03513 0.03131  0.02675  29  THR A CB  
398  O OG1 . THR A 29  ? 0.29807 0.39144 0.33235 -0.02746 0.04074  0.02344  29  THR A OG1 
399  C CG2 . THR A 29  ? 0.38841 0.46960 0.44474 -0.04704 0.02835  0.04570  29  THR A CG2 
407  N N   . HIS A 30  ? 0.41973 0.42628 0.45424 -0.03117 0.01389  0.00608  30  HIS A N   
408  C CA  . HIS A 30  ? 0.44680 0.42721 0.48268 -0.03306 0.00315  0.00007  30  HIS A CA  
409  C C   . HIS A 30  ? 0.47542 0.43551 0.50689 -0.02498 0.00158  -0.00432 30  HIS A C   
410  O O   . HIS A 30  ? 0.52660 0.46166 0.56008 -0.02472 -0.00803 -0.01002 30  HIS A O   
411  C CB  . HIS A 30  ? 0.41491 0.39157 0.44147 -0.02924 0.00092  -0.01363 30  HIS A CB  
412  C CG  . HIS A 30  ? 0.56518 0.54922 0.60160 -0.03925 -0.00697 -0.01076 30  HIS A CG  
413  N ND1 . HIS A 30  ? 0.49855 0.46713 0.53130 -0.04131 -0.01912 -0.02131 30  HIS A ND1 
414  C CD2 . HIS A 30  ? 0.43080 0.43907 0.48183 -0.04728 -0.00497 0.00116  30  HIS A CD2 
415  C CE1 . HIS A 30  ? 0.62056 0.60336 0.66755 -0.05176 -0.02583 -0.01512 30  HIS A CE1 
416  N NE2 . HIS A 30  ? 0.58151 0.58987 0.64126 -0.05518 -0.01637 -0.00069 30  HIS A NE2 
424  N N   . VAL A 31  ? 0.64822 0.61856 0.67549 -0.01788 0.00951  -0.00264 31  VAL A N   
425  C CA  . VAL A 31  ? 0.51003 0.46758 0.53593 -0.00802 0.00908  -0.00695 31  VAL A CA  
426  C C   . VAL A 31  ? 0.43250 0.38812 0.46721 -0.01020 0.00508  0.00779  31  VAL A C   
427  O O   . VAL A 31  ? 0.46174 0.39782 0.50160 -0.00418 -0.00086 0.00739  31  VAL A O   
428  C CB  . VAL A 31  ? 0.41951 0.39185 0.43867 0.00050  0.01872  -0.01401 31  VAL A CB  
429  C CG1 . VAL A 31  ? 0.62329 0.59595 0.64728 0.00865  0.01939  -0.01232 31  VAL A CG1 
430  C CG2 . VAL A 31  ? 0.47591 0.44380 0.48578 0.00592  0.02160  -0.02687 31  VAL A CG2 
440  N N   . ILE A 32  ? 0.44273 0.41924 0.47845 -0.01722 0.00822  0.02107  32  ILE A N   
441  C CA  . ILE A 32  ? 0.35134 0.33302 0.39048 -0.01758 0.00577  0.03688  32  ILE A CA  
442  C C   . ILE A 32  ? 0.42578 0.38170 0.47742 -0.02187 -0.00499 0.04775  32  ILE A C   
443  O O   . ILE A 32  ? 0.55373 0.49964 0.61335 -0.03215 -0.00994 0.05105  32  ILE A O   
444  C CB  . ILE A 32  ? 0.45187 0.46315 0.48612 -0.02413 0.01160  0.04888  32  ILE A CB  
445  C CG1 . ILE A 32  ? 0.66929 0.69059 0.70137 -0.02305 0.00916  0.06543  32  ILE A CG1 
446  C CG2 . ILE A 32  ? 0.51039 0.52618 0.55310 -0.03614 0.01110  0.05866  32  ILE A CG2 
447  C CD1 . ILE A 32  ? 0.55362 0.60804 0.57195 -0.02263 0.01637  0.06834  32  ILE A CD1 
459  N N   . PRO A 33  ? 0.52014 0.46336 0.57675 -0.01457 -0.01053 0.05374  33  PRO A N   
460  C CA  . PRO A 33  ? 0.39404 0.30739 0.46524 -0.01826 -0.02253 0.06524  33  PRO A CA  
461  C C   . PRO A 33  ? 0.40418 0.32828 0.48293 -0.03418 -0.02461 0.09116  33  PRO A C   
462  O O   . PRO A 33  ? 0.42401 0.37326 0.49729 -0.03544 -0.02042 0.10845  33  PRO A O   
463  C CB  . PRO A 33  ? 0.48021 0.38564 0.55523 -0.00450 -0.02645 0.06846  33  PRO A CB  
464  C CG  . PRO A 33  ? 0.64744 0.57360 0.71206 0.00677  -0.01700 0.05157  33  PRO A CG  
465  C CD  . PRO A 33  ? 0.50042 0.45452 0.55305 -0.00224 -0.00777 0.05000  33  PRO A CD  
473  N N   . GLN A 34  ? 0.46505 0.37216 0.55666 -0.04667 -0.03157 0.09430  34  GLN A N   
474  C CA  . GLN A 34  ? 0.42049 0.34548 0.52284 -0.06405 -0.03110 0.11960  34  GLN A CA  
475  C C   . GLN A 34  ? 0.60233 0.51667 0.71752 -0.06936 -0.03892 0.14894  34  GLN A C   
476  O O   . GLN A 34  ? 0.56080 0.50267 0.67905 -0.08035 -0.03410 0.17552  34  GLN A O   
477  C CB  . GLN A 34  ? 0.44629 0.35872 0.56329 -0.07759 -0.03802 0.11433  34  GLN A CB  
478  C CG  . GLN A 34  ? 0.75349 0.70217 0.87968 -0.09339 -0.03121 0.13329  34  GLN A CG  
479  C CD  . GLN A 34  ? 0.57166 0.55662 0.68121 -0.08671 -0.01664 0.11934  34  GLN A CD  
480  O OE1 . GLN A 34  ? 0.73620 0.71300 0.83264 -0.07570 -0.01507 0.09409  34  GLN A OE1 
481  N NE2 . GLN A 34  ? 0.59269 0.61833 0.70316 -0.09254 -0.00565 0.13653  34  GLN A NE2 
490  N N   . SER A 35  ? 0.58893 0.46557 0.71168 -0.06048 -0.05037 0.14583  35  SER A N   
491  C CA  . SER A 35  ? 0.50680 0.36545 0.64542 -0.06493 -0.06077 0.17491  35  SER A CA  
492  C C   . SER A 35  ? 0.43537 0.30086 0.56395 -0.04826 -0.05996 0.18069  35  SER A C   
493  O O   . SER A 35  ? 0.71161 0.54940 0.85392 -0.04382 -0.07174 0.19550  35  SER A O   
494  C CB  . SER A 35  ? 0.71848 0.52261 0.87966 -0.06817 -0.07852 0.16935  35  SER A CB  
495  O OG  . SER A 35  ? 0.83912 0.63866 1.01347 -0.08694 -0.08278 0.16838  35  SER A OG  
501  N N   . ALA A 36  ? 0.64678 0.54844 0.75372 -0.03915 -0.04783 0.16973  36  ALA A N   
502  C CA  . ALA A 36  ? 0.60277 0.51649 0.70113 -0.02448 -0.04846 0.17362  36  ALA A CA  
503  C C   . ALA A 36  ? 0.69219 0.63694 0.78232 -0.03109 -0.04702 0.20617  36  ALA A C   
504  O O   . ALA A 36  ? 0.74907 0.72377 0.82984 -0.04287 -0.03781 0.21612  36  ALA A O   
505  C CB  . ALA A 36  ? 0.51423 0.45110 0.59564 -0.01316 -0.03846 0.14605  36  ALA A CB  
511  N N   . LYS A 37  ? 0.48319 0.42342 0.57629 -0.02187 -0.05599 0.22300  37  LYS A N   
512  C CA  . LYS A 37  ? 0.65585 0.62946 0.73532 -0.02440 -0.05564 0.25293  37  LYS A CA  
513  C C   . LYS A 37  ? 0.64514 0.64878 0.70499 -0.01007 -0.05442 0.24123  37  LYS A C   
514  O O   . LYS A 37  ? 0.63775 0.66989 0.68253 -0.00909 -0.05666 0.26309  37  LYS A O   
515  C CB  . LYS A 37  ? 0.73223 0.68057 0.83037 -0.02663 -0.06952 0.28810  37  LYS A CB  
516  C CG  . LYS A 37  ? 0.63777 0.56736 0.75456 -0.04555 -0.07083 0.30463  37  LYS A CG  
517  C CD  . LYS A 37  ? 0.91114 0.83733 1.03712 -0.04880 -0.07845 0.33177  37  LYS A CD  
518  C CE  . LYS A 37  ? 0.94188 0.85209 1.09014 -0.06749 -0.08052 0.34269  37  LYS A CE  
519  N NZ  . LYS A 37  ? 0.75138 0.62892 0.91508 -0.07307 -0.08303 0.31773  37  LYS A NZ  
533  N N   . GLU A 38  ? 0.45277 0.45270 0.51263 0.00024  -0.05160 0.20829  38  GLU A N   
534  C CA  . GLU A 38  ? 0.58566 0.61133 0.63433 0.01222  -0.05310 0.19689  38  GLU A CA  
535  C C   . GLU A 38  ? 0.51116 0.53711 0.55996 0.01670  -0.04507 0.16161  38  GLU A C   
536  O O   . GLU A 38  ? 0.53849 0.53644 0.60079 0.01791  -0.04279 0.14685  38  GLU A O   
537  C CB  . GLU A 38  ? 0.55006 0.56254 0.61498 0.02567  -0.06715 0.20966  38  GLU A CB  
538  C CG  . GLU A 38  ? 0.83723 0.87395 0.90028 0.03862  -0.07096 0.19538  38  GLU A CG  
539  C CD  . GLU A 38  ? 0.75135 0.76529 0.84201 0.05497  -0.07913 0.19016  38  GLU A CD  
540  O OE1 . GLU A 38  ? 0.76842 0.76071 0.87160 0.05935  -0.07291 0.16751  38  GLU A OE1 
541  O OE2 . GLU A 38  ? 0.73065 0.75015 0.82990 0.06476  -0.09161 0.20893  38  GLU A OE2 
548  N N   . PHE A 39  ? 0.43191 0.48930 0.46500 0.01886  -0.04178 0.14875  39  PHE A N   
549  C CA  . PHE A 39  ? 0.61197 0.67233 0.64780 0.02284  -0.03573 0.11951  39  PHE A CA  
550  C C   . PHE A 39  ? 0.35909 0.44418 0.39439 0.03065  -0.04299 0.11485  39  PHE A C   
551  O O   . PHE A 39  ? 0.51184 0.62351 0.52841 0.02824  -0.04696 0.12128  39  PHE A O   
552  C CB  . PHE A 39  ? 0.47493 0.54615 0.49520 0.01372  -0.02416 0.10519  39  PHE A CB  
553  C CG  . PHE A 39  ? 0.54121 0.58970 0.56756 0.00655  -0.01768 0.10376  39  PHE A CG  
554  C CD1 . PHE A 39  ? 0.51872 0.53665 0.56225 0.01079  -0.01947 0.09622  39  PHE A CD1 
555  C CD2 . PHE A 39  ? 0.44813 0.50825 0.46325 -0.00354 -0.01041 0.10894  39  PHE A CD2 
556  C CE1 . PHE A 39  ? 0.61907 0.61631 0.66711 0.00362  -0.01652 0.09310  39  PHE A CE1 
557  C CE2 . PHE A 39  ? 0.37560 0.41783 0.39967 -0.01122 -0.00667 0.10822  39  PHE A CE2 
558  C CZ  . PHE A 39  ? 0.45812 0.46779 0.49799 -0.00839 -0.01093 0.09990  39  PHE A CZ  
568  N N   . PHE A 40  ? 0.48827 0.56723 0.54427 0.04028  -0.04509 0.10353  40  PHE A N   
569  C CA  . PHE A 40  ? 0.39735 0.50173 0.46089 0.04682  -0.05318 0.09929  40  PHE A CA  
570  C C   . PHE A 40  ? 0.41679 0.53701 0.47397 0.05023  -0.06718 0.12211  40  PHE A C   
571  O O   . PHE A 40  ? 0.48729 0.63663 0.53530 0.04987  -0.07552 0.12053  40  PHE A O   
572  C CB  . PHE A 40  ? 0.39446 0.51957 0.44659 0.03939  -0.04894 0.07975  40  PHE A CB  
573  C CG  . PHE A 40  ? 0.50043 0.61087 0.55611 0.03531  -0.03554 0.06152  40  PHE A CG  
574  C CD1 . PHE A 40  ? 0.37772 0.47733 0.45540 0.04232  -0.03060 0.05337  40  PHE A CD1 
575  C CD2 . PHE A 40  ? 0.46136 0.57117 0.49792 0.02613  -0.02763 0.05331  40  PHE A CD2 
576  C CE1 . PHE A 40  ? 0.40636 0.49483 0.48419 0.03906  -0.01873 0.03884  40  PHE A CE1 
577  C CE2 . PHE A 40  ? 0.35079 0.44773 0.39088 0.02311  -0.01681 0.03888  40  PHE A CE2 
578  C CZ  . PHE A 40  ? 0.38936 0.47559 0.44873 0.02898  -0.01270 0.03238  40  PHE A CZ  
588  N N   . GLY A 41  ? 0.59580 0.69562 0.65795 0.05327  -0.07130 0.14409  41  GLY A N   
589  C CA  . GLY A 41  ? 0.46522 0.57692 0.52236 0.05704  -0.08477 0.17119  41  GLY A CA  
590  C C   . GLY A 41  ? 0.52073 0.65061 0.54602 0.04653  -0.08386 0.18737  41  GLY A C   
591  O O   . GLY A 41  ? 0.50108 0.64086 0.51914 0.04891  -0.09424 0.21479  41  GLY A O   
595  N N   . VAL A 42  ? 0.53757 0.67442 0.54368 0.03635  -0.07144 0.17277  42  VAL A N   
596  C CA  . VAL A 42  ? 0.42899 0.58969 0.40368 0.02868  -0.06786 0.18552  42  VAL A CA  
597  C C   . VAL A 42  ? 0.55293 0.69489 0.53070 0.01998  -0.06020 0.20732  42  VAL A C   
598  O O   . VAL A 42  ? 0.42093 0.53689 0.41395 0.01532  -0.05185 0.19588  42  VAL A O   
599  C CB  . VAL A 42  ? 0.54208 0.72208 0.49619 0.02436  -0.05878 0.15765  42  VAL A CB  
600  C CG1 . VAL A 42  ? 0.52936 0.73899 0.44885 0.02030  -0.05423 0.16900  42  VAL A CG1 
601  C CG2 . VAL A 42  ? 0.59826 0.79214 0.55582 0.02993  -0.06794 0.13505  42  VAL A CG2 
611  N N   . PRO A 43  ? 0.61711 0.77288 0.58170 0.01658  -0.06335 0.23978  43  PRO A N   
612  C CA  . PRO A 43  ? 0.59321 0.73592 0.56363 0.00481  -0.05545 0.26237  43  PRO A CA  
613  C C   . PRO A 43  ? 0.52498 0.68042 0.48360 -0.00379 -0.03886 0.24441  43  PRO A C   
614  O O   . PRO A 43  ? 0.57121 0.75971 0.50289 -0.00165 -0.03278 0.23042  43  PRO A O   
615  C CB  . PRO A 43  ? 0.48835 0.65641 0.44115 0.00322  -0.06078 0.30141  43  PRO A CB  
616  C CG  . PRO A 43  ? 0.60927 0.78689 0.55827 0.01641  -0.07649 0.30153  43  PRO A CG  
617  C CD  . PRO A 43  ? 0.63876 0.82328 0.58492 0.02279  -0.07557 0.26048  43  PRO A CD  
625  N N   . ILE A 44  ? 0.66237 0.79057 0.64221 -0.01269 -0.03295 0.24389  44  ILE A N   
626  C CA  . ILE A 44  ? 0.54793 0.68537 0.52292 -0.01953 -0.01863 0.22538  44  ILE A CA  
627  C C   . ILE A 44  ? 0.44799 0.62828 0.39894 -0.02465 -0.00778 0.24127  44  ILE A C   
628  O O   . ILE A 44  ? 0.54929 0.75066 0.48647 -0.02389 0.00377  0.22112  44  ILE A O   
629  C CB  . ILE A 44  ? 0.65268 0.75399 0.65622 -0.02888 -0.01788 0.22560  44  ILE A CB  
630  C CG1 . ILE A 44  ? 0.43538 0.54353 0.43711 -0.03311 -0.00565 0.20145  44  ILE A CG1 
631  C CG2 . ILE A 44  ? 0.57523 0.67293 0.59154 -0.04163 -0.02006 0.26391  44  ILE A CG2 
632  C CD1 . ILE A 44  ? 0.53582 0.64205 0.53006 -0.02284 -0.00397 0.16642  44  ILE A CD1 
644  N N   . LYS A 45  ? 0.55063 0.74584 0.49625 -0.02871 -0.01070 0.27825  45  LYS A N   
645  C CA  . LYS A 45  ? 0.57685 0.81385 0.50209 -0.03017 0.00096  0.28328  45  LYS A CA  
646  C C   . LYS A 45  ? 0.66810 0.93710 0.55750 -0.01765 0.00327  0.25883  45  LYS A C   
647  O O   . LYS A 45  ? 0.60605 0.90539 0.47848 -0.01558 0.01563  0.24746  45  LYS A O   
648  C CB  . LYS A 45  ? 0.58004 0.82164 0.51084 -0.03398 -0.00412 0.31459  45  LYS A CB  
649  C CG  . LYS A 45  ? 0.91616 1.20085 0.83071 -0.03559 0.00843  0.32327  45  LYS A CG  
650  C CD  . LYS A 45  ? 1.06481 1.34925 1.00660 -0.04971 0.01713  0.33905  45  LYS A CD  
651  C CE  . LYS A 45  ? 0.94143 1.27326 0.86742 -0.04796 0.03309  0.33721  45  LYS A CE  
652  N NZ  . LYS A 45  ? 0.86739 1.21314 0.77537 -0.03870 0.04250  0.30223  45  LYS A NZ  
666  N N   . GLN A 46  ? 0.69352 0.95544 0.57385 -0.00846 -0.01003 0.24867  46  GLN A N   
667  C CA  . GLN A 46  ? 0.59959 0.88734 0.44912 0.00224  -0.01243 0.22213  46  GLN A CA  
668  C C   . GLN A 46  ? 0.55496 0.83390 0.40695 0.00452  -0.00587 0.18266  46  GLN A C   
669  O O   . GLN A 46  ? 0.57714 0.87533 0.40484 0.01218  -0.00704 0.15765  46  GLN A O   
670  C CB  . GLN A 46  ? 0.59099 0.87324 0.43969 0.01005  -0.03187 0.22283  46  GLN A CB  
671  C CG  . GLN A 46  ? 0.67822 0.96370 0.52800 0.01010  -0.03982 0.25366  46  GLN A CG  
672  C CD  . GLN A 46  ? 1.00283 1.32022 0.82050 0.01786  -0.04575 0.24616  46  GLN A CD  
673  O OE1 . GLN A 46  ? 1.05667 1.39837 0.84843 0.02055  -0.03696 0.22559  46  GLN A OE1 
674  N NE2 . GLN A 46  ? 0.92926 1.24498 0.74936 0.02261  -0.06154 0.26132  46  GLN A NE2 
683  N N   . ILE A 47  ? 0.54012 0.78810 0.42152 -0.00173 -0.00061 0.17534  47  ILE A N   
684  C CA  . ILE A 47  ? 0.36324 0.59753 0.25185 0.00017  0.00433  0.14052  47  ILE A CA  
685  C C   . ILE A 47  ? 0.48140 0.73223 0.36494 -0.00302 0.02066  0.13728  47  ILE A C   
686  O O   . ILE A 47  ? 0.59252 0.84427 0.48930 -0.01182 0.02753  0.16038  47  ILE A O   
687  C CB  . ILE A 47  ? 0.39932 0.59266 0.32059 -0.00271 -0.00042 0.13390  47  ILE A CB  
688  C CG1 . ILE A 47  ? 0.43574 0.61724 0.36573 0.00280  -0.01540 0.13861  47  ILE A CG1 
689  C CG2 . ILE A 47  ? 0.39851 0.57999 0.32604 -0.00110 0.00490  0.10195  47  ILE A CG2 
690  C CD1 . ILE A 47  ? 0.47350 0.61753 0.43442 0.00254  -0.01908 0.13662  47  ILE A CD1 
702  N N   . GLN A 48  ? 0.57743 0.84106 0.44504 0.00414  0.02589  0.10882  48  GLN A N   
703  C CA  . GLN A 48  ? 0.38581 0.66795 0.24929 0.00504  0.04141  0.10187  48  GLN A CA  
704  C C   . GLN A 48  ? 0.48461 0.73700 0.37376 0.00208  0.04381  0.08351  48  GLN A C   
705  O O   . GLN A 48  ? 0.40707 0.64316 0.29678 0.00714  0.03898  0.05693  48  GLN A O   
706  C CB  . GLN A 48  ? 0.48146 0.79320 0.31150 0.01745  0.04487  0.08013  48  GLN A CB  
707  C CG  . GLN A 48  ? 0.77433 1.10691 0.57926 0.02205  0.03682  0.09009  48  GLN A CG  
708  C CD  . GLN A 48  ? 0.85591 1.21313 0.63995 0.03235  0.04347  0.07515  48  GLN A CD  
709  O OE1 . GLN A 48  ? 1.02250 1.37658 0.79505 0.04146  0.04192  0.04274  48  GLN A OE1 
710  N NE2 . GLN A 48  ? 0.90608 1.28690 0.68644 0.03107  0.05048  0.09919  48  GLN A NE2 
719  N N   . ILE A 49  ? 0.30856 0.55474 0.21956 -0.00695 0.05014  0.09893  49  ILE A N   
720  C CA  . ILE A 49  ? 0.32967 0.54815 0.26400 -0.01047 0.05053  0.08533  49  ILE A CA  
721  C C   . ILE A 49  ? 0.44490 0.68462 0.38233 -0.00912 0.06345  0.08026  49  ILE A C   
722  O O   . ILE A 49  ? 0.28920 0.55651 0.22921 -0.01382 0.07203  0.10113  49  ILE A O   
723  C CB  . ILE A 49  ? 0.39169 0.58180 0.35064 -0.02132 0.04368  0.10288  49  ILE A CB  
724  C CG1 . ILE A 49  ? 0.28797 0.46205 0.24479 -0.01965 0.03164  0.11057  49  ILE A CG1 
725  C CG2 . ILE A 49  ? 0.39419 0.55671 0.37092 -0.02291 0.04254  0.08548  49  ILE A CG2 
726  C CD1 . ILE A 49  ? 0.36864 0.50584 0.34890 -0.02488 0.02303  0.11657  49  ILE A CD1 
738  N N   . HIS A 50  ? 0.36716 0.59588 0.30679 -0.00252 0.06482  0.05449  50  HIS A N   
739  C CA  . HIS A 50  ? 0.49575 0.74042 0.44262 0.00121  0.07536  0.04705  50  HIS A CA  
740  C C   . HIS A 50  ? 0.46579 0.68079 0.43535 -0.00364 0.07115  0.03964  50  HIS A C   
741  O O   . HIS A 50  ? 0.45836 0.64361 0.42931 -0.00314 0.06290  0.02734  50  HIS A O   
742  C CB  . HIS A 50  ? 0.46074 0.71979 0.38739 0.01654  0.08002  0.02212  50  HIS A CB  
743  C CG  . HIS A 50  ? 0.84888 1.13939 0.74880 0.02349  0.08379  0.02603  50  HIS A CG  
744  N ND1 . HIS A 50  ? 0.81278 1.12067 0.70448 0.03480  0.08982  0.01503  50  HIS A ND1 
745  C CD2 . HIS A 50  ? 0.86356 1.16213 0.74650 0.02090  0.07823  0.03951  50  HIS A CD2 
746  C CE1 . HIS A 50  ? 0.93342 1.26027 0.80302 0.03866  0.08868  0.02040  50  HIS A CE1 
747  N NE2 . HIS A 50  ? 0.82023 1.14181 0.68434 0.03020  0.08114  0.03573  50  HIS A NE2 
755  N N   . LYS A 51  ? 0.41160 0.63816 0.39925 -0.00846 0.07663  0.04846  51  LYS A N   
756  C CA  . LYS A 51  ? 0.45950 0.66263 0.46651 -0.01315 0.07162  0.04305  51  LYS A CA  
757  C C   . LYS A 51  ? 0.39861 0.61979 0.41293 -0.00494 0.07925  0.03278  51  LYS A C   
758  O O   . LYS A 51  ? 0.42979 0.68656 0.44958 -0.00344 0.08889  0.04248  51  LYS A O   
759  C CB  . LYS A 51  ? 0.27097 0.46734 0.29783 -0.02843 0.06622  0.06375  51  LYS A CB  
760  C CG  . LYS A 51  ? 0.37404 0.56019 0.39710 -0.03576 0.06028  0.08043  51  LYS A CG  
761  C CD  . LYS A 51  ? 0.59472 0.74634 0.60960 -0.03186 0.05107  0.06783  51  LYS A CD  
762  C CE  . LYS A 51  ? 0.51921 0.63981 0.54795 -0.03637 0.04308  0.06066  51  LYS A CE  
763  N NZ  . LYS A 51  ? 0.79288 0.88537 0.82454 -0.03956 0.03331  0.06631  51  LYS A NZ  
777  N N   . SER A 52  ? 0.49881 0.69754 0.51474 0.00110  0.07536  0.01493  52  SER A N   
778  C CA  . SER A 52  ? 0.35765 0.56688 0.38386 0.00988  0.07989  0.00575  52  SER A CA  
779  C C   . SER A 52  ? 0.29649 0.48148 0.33667 0.00369  0.07127  0.00558  52  SER A C   
780  O O   . SER A 52  ? 0.25990 0.41813 0.29455 0.00722  0.06624  -0.00627 52  SER A O   
781  C CB  . SER A 52  ? 0.49009 0.69479 0.50271 0.02524  0.08247  -0.01575 52  SER A CB  
782  O OG  . SER A 52  ? 0.67529 0.87292 0.70034 0.03293  0.08199  -0.02504 52  SER A OG  
788  N N   . GLY A 53  ? 0.24275 0.43897 0.30096 -0.00594 0.06905  0.01926  53  GLY A N   
789  C CA  . GLY A 53  ? 0.23501 0.40908 0.30217 -0.01220 0.05874  0.01826  53  GLY A CA  
790  C C   . GLY A 53  ? 0.34874 0.48967 0.40408 -0.01791 0.05114  0.01581  53  GLY A C   
791  O O   . GLY A 53  ? 0.38599 0.52322 0.44093 -0.02633 0.04872  0.02573  53  GLY A O   
795  N N   . GLU A 54  ? 0.31383 0.43172 0.36085 -0.01249 0.04776  0.00395  54  GLU A N   
796  C CA  . GLU A 54  ? 0.33735 0.42822 0.37453 -0.01506 0.04244  0.00044  54  GLU A CA  
797  C C   . GLU A 54  ? 0.32912 0.41445 0.35464 -0.00935 0.04625  -0.00579 54  GLU A C   
798  O O   . GLU A 54  ? 0.45863 0.52624 0.47879 -0.00990 0.04305  -0.00830 54  GLU A O   
799  C CB  . GLU A 54  ? 0.39545 0.46946 0.43023 -0.01306 0.03732  -0.00631 54  GLU A CB  
800  C CG  . GLU A 54  ? 0.47757 0.55253 0.52125 -0.02036 0.02890  -0.00202 54  GLU A CG  
801  C CD  . GLU A 54  ? 0.44006 0.50234 0.48602 -0.02996 0.02180  0.00259  54  GLU A CD  
802  O OE1 . GLU A 54  ? 0.44905 0.49247 0.48495 -0.02768 0.02136  -0.00161 54  GLU A OE1 
803  O OE2 . GLU A 54  ? 0.51129 0.58258 0.57199 -0.03974 0.01614  0.01113  54  GLU A OE2 
810  N N   . PHE A 55  ? 0.28560 0.38723 0.30773 -0.00324 0.05227  -0.00936 55  PHE A N   
811  C CA  . PHE A 55  ? 0.47053 0.56887 0.48179 0.00120  0.05311  -0.01679 55  PHE A CA  
812  C C   . PHE A 55  ? 0.32684 0.43788 0.33201 -0.00257 0.05343  -0.00687 55  PHE A C   
813  O O   . PHE A 55  ? 0.34215 0.47698 0.34703 -0.00259 0.05860  0.00056  55  PHE A O   
814  C CB  . PHE A 55  ? 0.43113 0.53723 0.43958 0.01100  0.05713  -0.02912 55  PHE A CB  
815  C CG  . PHE A 55  ? 0.47265 0.56958 0.47245 0.01445  0.05426  -0.04067 55  PHE A CG  
816  C CD1 . PHE A 55  ? 0.39200 0.46766 0.39692 0.01392  0.05020  -0.04692 55  PHE A CD1 
817  C CD2 . PHE A 55  ? 0.28701 0.39912 0.27410 0.01762  0.05495  -0.04436 55  PHE A CD2 
818  C CE1 . PHE A 55  ? 0.33501 0.40358 0.33716 0.01471  0.04572  -0.05675 55  PHE A CE1 
819  C CE2 . PHE A 55  ? 0.42590 0.53019 0.40601 0.01978  0.04929  -0.05654 55  PHE A CE2 
820  C CZ  . PHE A 55  ? 0.35413 0.43605 0.34412 0.01748  0.04409  -0.06288 55  PHE A CZ  
830  N N   . CYS A 56  ? 0.36728 0.46517 0.36884 -0.00511 0.04832  -0.00477 56  CYS A N   
831  C CA  . CYS A 56  ? 0.36073 0.46741 0.35692 -0.00818 0.04648  0.00724  56  CYS A CA  
832  C C   . CYS A 56  ? 0.45612 0.56666 0.44045 -0.00270 0.04407  -0.00112 56  CYS A C   
833  O O   . CYS A 56  ? 0.41685 0.51278 0.40407 -0.00085 0.04023  -0.01099 56  CYS A O   
834  C CB  . CYS A 56  ? 0.33191 0.41933 0.33641 -0.01420 0.04005  0.01716  56  CYS A CB  
835  S SG  . CYS A 56  ? 0.47308 0.56873 0.47661 -0.01956 0.03666  0.03893  56  CYS A SG  
841  N N   . ARG A 57  ? 0.43164 0.56450 0.40299 -0.00056 0.04592  0.00364  57  ARG A N   
842  C CA  . ARG A 57  ? 0.35927 0.50047 0.31571 0.00542  0.04223  -0.00773 57  ARG A CA  
843  C C   . ARG A 57  ? 0.37887 0.53400 0.32454 0.00393  0.03810  0.00774  57  ARG A C   
844  O O   . ARG A 57  ? 0.40847 0.58437 0.34691 0.00259  0.04355  0.02283  57  ARG A O   
845  C CB  . ARG A 57  ? 0.35100 0.50901 0.29581 0.01358  0.04840  -0.02202 57  ARG A CB  
846  C CG  . ARG A 57  ? 0.45186 0.61106 0.38242 0.02026  0.04200  -0.04170 57  ARG A CG  
847  C CD  . ARG A 57  ? 0.40220 0.57838 0.31885 0.03121  0.04864  -0.05702 57  ARG A CD  
848  N NE  . ARG A 57  ? 0.64142 0.84283 0.53126 0.03747  0.04726  -0.06044 57  ARG A NE  
849  C CZ  . ARG A 57  ? 0.98272 1.18266 0.85669 0.04431  0.03870  -0.08301 57  ARG A CZ  
850  N NH1 . ARG A 57  ? 0.82012 0.99316 0.70589 0.04474  0.03093  -0.10325 57  ARG A NH1 
851  N NH2 . ARG A 57  ? 0.55445 0.78067 0.39992 0.05032  0.03689  -0.08471 57  ARG A NH2 
865  N N   . LEU A 58  ? 0.32740 0.47386 0.27388 0.00415  0.02850  0.00637  58  LEU A N   
866  C CA  . LEU A 58  ? 0.28884 0.44614 0.22748 0.00363  0.02211  0.02310  58  LEU A CA  
867  C C   . LEU A 58  ? 0.39807 0.57094 0.31891 0.00916  0.01427  0.01105  58  LEU A C   
868  O O   . LEU A 58  ? 0.36542 0.52803 0.29459 0.00982  0.00611  -0.00237 58  LEU A O   
869  C CB  . LEU A 58  ? 0.30977 0.44575 0.26709 0.00092  0.01545  0.03348  58  LEU A CB  
870  C CG  . LEU A 58  ? 0.47096 0.59163 0.44212 -0.00484 0.01885  0.04882  58  LEU A CG  
871  C CD1 . LEU A 58  ? 0.41650 0.52268 0.39775 -0.00668 0.02497  0.03586  58  LEU A CD1 
872  C CD2 . LEU A 58  ? 0.55562 0.65763 0.54040 -0.00417 0.01038  0.06007  58  LEU A CD2 
884  N N   . ARG A 59  ? 0.40668 0.60652 0.30338 0.01277  0.01633  0.01629  59  ARG A N   
885  C CA  . ARG A 59  ? 0.43351 0.65133 0.30756 0.01854  0.00670  0.00571  59  ARG A CA  
886  C C   . ARG A 59  ? 0.50861 0.73716 0.37758 0.01743  -0.00236 0.02934  59  ARG A C   
887  O O   . ARG A 59  ? 0.40233 0.64520 0.26340 0.01583  0.00330  0.05398  59  ARG A O   
888  C CB  . ARG A 59  ? 0.43742 0.68171 0.28275 0.02627  0.01452  -0.00479 59  ARG A CB  
889  C CG  . ARG A 59  ? 0.68654 0.95263 0.50137 0.03331  0.00338  -0.01597 59  ARG A CG  
890  C CD  . ARG A 59  ? 0.64813 0.89591 0.47000 0.03367  -0.01105 -0.04463 59  ARG A CD  
891  N NE  . ARG A 59  ? 0.80679 1.04313 0.62903 0.03844  -0.00556 -0.07175 59  ARG A NE  
892  C CZ  . ARG A 59  ? 0.67953 0.89509 0.51268 0.03742  -0.01626 -0.09686 59  ARG A CZ  
893  N NH1 . ARG A 59  ? 0.87221 1.07983 0.71848 0.03087  -0.03248 -0.09907 59  ARG A NH1 
894  N NH2 . ARG A 59  ? 0.86998 1.07302 0.70410 0.04296  -0.01102 -0.11887 59  ARG A NH2 
908  N N   . PHE A 60  ? 0.49156 0.71488 0.36744 0.01805  -0.01675 0.02382  60  PHE A N   
909  C CA  . PHE A 60  ? 0.37364 0.60723 0.24705 0.01896  -0.02765 0.04592  60  PHE A CA  
910  C C   . PHE A 60  ? 0.52926 0.79487 0.36766 0.02465  -0.03612 0.04333  60  PHE A C   
911  O O   . PHE A 60  ? 0.49366 0.76799 0.31422 0.02832  -0.03817 0.01689  60  PHE A O   
912  C CB  . PHE A 60  ? 0.33207 0.54909 0.23384 0.01830  -0.03906 0.04285  60  PHE A CB  
913  C CG  . PHE A 60  ? 0.30727 0.49621 0.23854 0.01526  -0.03147 0.04975  60  PHE A CG  
914  C CD1 . PHE A 60  ? 0.36398 0.53519 0.30876 0.01251  -0.02300 0.03176  60  PHE A CD1 
915  C CD2 . PHE A 60  ? 0.39477 0.57398 0.33880 0.01597  -0.03369 0.07400  60  PHE A CD2 
916  C CE1 . PHE A 60  ? 0.34292 0.49059 0.30971 0.01087  -0.01668 0.03645  60  PHE A CE1 
917  C CE2 . PHE A 60  ? 0.48623 0.63797 0.45428 0.01465  -0.02802 0.07630  60  PHE A CE2 
918  C CZ  . PHE A 60  ? 0.45554 0.59319 0.43303 0.01226  -0.01934 0.05686  60  PHE A CZ  
928  N N   . PRO A 61  ? 0.40313 0.68602 0.22967 0.02621  -0.04206 0.07059  61  PRO A N   
929  C CA  . PRO A 61  ? 0.44115 0.75923 0.22799 0.03263  -0.04969 0.07022  61  PRO A CA  
930  C C   . PRO A 61  ? 0.70769 1.03153 0.49073 0.03568  -0.07040 0.04869  61  PRO A C   
931  O O   . PRO A 61  ? 0.56822 0.91154 0.31991 0.04085  -0.07623 0.02757  61  PRO A O   
932  C CB  . PRO A 61  ? 0.46107 0.79239 0.24247 0.03204  -0.05067 0.11150  61  PRO A CB  
933  C CG  . PRO A 61  ? 0.49445 0.79250 0.31805 0.02742  -0.05433 0.12545  61  PRO A CG  
934  C CD  . PRO A 61  ? 0.44340 0.71361 0.29077 0.02300  -0.04285 0.10318  61  PRO A CD  
942  N N   . LYS A 62  ? 0.61558 0.92363 0.43142 0.03296  -0.08204 0.05283  62  LYS A N   
943  C CA  . LYS A 62  ? 0.66938 0.98336 0.49287 0.03335  -0.10236 0.03417  62  LYS A CA  
944  C C   . LYS A 62  ? 0.48151 0.76839 0.34308 0.02742  -0.09993 0.01393  62  LYS A C   
945  O O   . LYS A 62  ? 0.54169 0.80526 0.42435 0.02459  -0.08444 0.01950  62  LYS A O   
946  C CB  . LYS A 62  ? 0.57827 0.90469 0.41244 0.03637  -0.11883 0.05927  62  LYS A CB  
947  C CG  . LYS A 62  ? 0.74616 1.09332 0.55143 0.04117  -0.11829 0.09214  62  LYS A CG  
948  C CD  . LYS A 62  ? 0.92653 1.25432 0.76182 0.04098  -0.11389 0.12564  62  LYS A CD  
949  C CE  . LYS A 62  ? 0.85343 1.19161 0.66633 0.04178  -0.10701 0.16004  62  LYS A CE  
950  N NZ  . LYS A 62  ? 0.74437 1.05479 0.58674 0.03871  -0.09841 0.18705  62  LYS A NZ  
964  N N   . PRO A 63  ? 0.48073 0.77093 0.35205 0.02462  -0.11541 -0.00910 63  PRO A N   
965  C CA  . PRO A 63  ? 0.52733 0.79560 0.43874 0.01782  -0.11307 -0.02227 63  PRO A CA  
966  C C   . PRO A 63  ? 0.35786 0.62103 0.30611 0.01850  -0.11248 -0.00066 63  PRO A C   
967  O O   . PRO A 63  ? 0.46763 0.74834 0.42026 0.02281  -0.12577 0.01533  63  PRO A O   
968  C CB  . PRO A 63  ? 0.47637 0.75444 0.39004 0.01328  -0.13357 -0.04788 63  PRO A CB  
969  C CG  . PRO A 63  ? 0.58071 0.88872 0.46210 0.01901  -0.15104 -0.04311 63  PRO A CG  
970  C CD  . PRO A 63  ? 0.44652 0.76108 0.29148 0.02660  -0.13600 -0.02550 63  PRO A CD  
978  N N   . ILE A 64  ? 0.43334 0.67313 0.40673 0.01597  -0.09716 -0.00052 64  ILE A N   
979  C CA  . ILE A 64  ? 0.53288 0.76522 0.53937 0.01930  -0.09354 0.01613  64  ILE A CA  
980  C C   . ILE A 64  ? 0.36914 0.60317 0.41314 0.01503  -0.09696 0.00511  64  ILE A C   
981  O O   . ILE A 64  ? 0.32951 0.57739 0.40028 0.01899  -0.10542 0.01478  64  ILE A O   
982  C CB  . ILE A 64  ? 0.41331 0.62057 0.41935 0.02080  -0.07426 0.02566  64  ILE A CB  
983  C CG1 . ILE A 64  ? 0.50901 0.71718 0.49935 0.02606  -0.07447 0.05035  64  ILE A CG1 
984  C CG2 . ILE A 64  ? 0.50965 0.70254 0.55058 0.02271  -0.06667 0.02677  64  ILE A CG2 
985  C CD1 . ILE A 64  ? 0.51614 0.74064 0.46778 0.02505  -0.07606 0.05308  64  ILE A CD1 
997  N N   . ARG A 65  ? 0.41559 0.63731 0.46453 0.00727  -0.09008 -0.01309 65  ARG A N   
998  C CA  . ARG A 65  ? 0.34014 0.56479 0.42617 0.00079  -0.09183 -0.02062 65  ARG A CA  
999  C C   . ARG A 65  ? 0.37859 0.61606 0.46447 -0.00807 -0.11079 -0.03827 65  ARG A C   
1000 O O   . ARG A 65  ? 0.50250 0.72609 0.58429 -0.01572 -0.11003 -0.05599 65  ARG A O   
1001 C CB  . ARG A 65  ? 0.33284 0.53433 0.42724 -0.00267 -0.07313 -0.02563 65  ARG A CB  
1002 C CG  . ARG A 65  ? 0.37001 0.56105 0.47399 0.00539  -0.05762 -0.01130 65  ARG A CG  
1003 C CD  . ARG A 65  ? 0.45684 0.66545 0.59667 0.01021  -0.06004 -0.00181 65  ARG A CD  
1004 N NE  . ARG A 65  ? 0.37724 0.59758 0.54701 0.00099  -0.06127 -0.00888 65  ARG A NE  
1005 C CZ  . ARG A 65  ? 0.41357 0.62571 0.59811 -0.00188 -0.04637 -0.00994 65  ARG A CZ  
1006 N NH1 . ARG A 65  ? 0.27470 0.46695 0.44573 0.00474  -0.03013 -0.00720 65  ARG A NH1 
1007 N NH2 . ARG A 65  ? 0.22063 0.44572 0.43446 -0.01244 -0.04883 -0.01282 65  ARG A NH2 
1021 N N   . THR A 66  ? 0.39599 0.65920 0.48728 -0.00654 -0.12998 -0.03369 66  THR A N   
1022 C CA  . THR A 66  ? 0.40714 0.68414 0.49752 -0.01507 -0.15245 -0.05166 66  THR A CA  
1023 C C   . THR A 66  ? 0.41687 0.69291 0.55002 -0.02849 -0.15648 -0.06139 66  THR A C   
1024 O O   . THR A 66  ? 0.47694 0.75522 0.61176 -0.03857 -0.17495 -0.08039 66  THR A O   
1025 C CB  . THR A 66  ? 0.35787 0.66623 0.44711 -0.01009 -0.17362 -0.04168 66  THR A CB  
1026 O OG1 . THR A 66  ? 0.45947 0.78227 0.58935 -0.00556 -0.17107 -0.02167 66  THR A OG1 
1027 C CG2 . THR A 66  ? 0.46135 0.77236 0.50363 0.00097  -0.17242 -0.03174 66  THR A CG2 
1035 N N   . ASP A 67  ? 0.45158 0.72468 0.61894 -0.02901 -0.14016 -0.04877 67  ASP A N   
1036 C CA  . ASP A 67  ? 0.45576 0.73285 0.66680 -0.04254 -0.14185 -0.05232 67  ASP A CA  
1037 C C   . ASP A 67  ? 0.30357 0.54960 0.50832 -0.05162 -0.13293 -0.06634 67  ASP A C   
1038 O O   . ASP A 67  ? 0.33709 0.58273 0.57499 -0.06590 -0.13892 -0.07107 67  ASP A O   
1039 C CB  . ASP A 67  ? 0.26646 0.55826 0.51518 -0.03749 -0.12611 -0.03223 67  ASP A CB  
1040 C CG  . ASP A 67  ? 0.50379 0.77442 0.73153 -0.02493 -0.10173 -0.02352 67  ASP A CG  
1041 O OD1 . ASP A 67  ? 0.49858 0.75490 0.68720 -0.01684 -0.10033 -0.02459 67  ASP A OD1 
1042 O OD2 . ASP A 67  ? 0.50704 0.77719 0.75744 -0.02348 -0.08442 -0.01527 67  ASP A OD2 
1047 N N   . VAL A 68  ? 0.40778 0.62894 0.57446 -0.04411 -0.11958 -0.07130 68  VAL A N   
1048 C CA  . VAL A 68  ? 0.31891 0.51091 0.48206 -0.04957 -0.10889 -0.08113 68  VAL A CA  
1049 C C   . VAL A 68  ? 0.46910 0.64610 0.60515 -0.05214 -0.12340 -0.10599 68  VAL A C   
1050 O O   . VAL A 68  ? 0.58277 0.77190 0.69210 -0.04713 -0.13753 -0.11504 68  VAL A O   
1051 C CB  . VAL A 68  ? 0.30198 0.47739 0.44503 -0.03925 -0.08477 -0.07136 68  VAL A CB  
1052 C CG1 . VAL A 68  ? 0.40075 0.59053 0.56334 -0.03280 -0.07270 -0.05071 68  VAL A CG1 
1053 C CG2 . VAL A 68  ? 0.49480 0.66490 0.59297 -0.02914 -0.08404 -0.07707 68  VAL A CG2 
1063 N N   . THR A 69  ? 0.42998 0.58043 0.57222 -0.05873 -0.12007 -0.11727 69  THR A N   
1064 C CA  . THR A 69  ? 0.40110 0.53047 0.51730 -0.05766 -0.13015 -0.14337 69  THR A CA  
1065 C C   . THR A 69  ? 0.33662 0.44723 0.42249 -0.04571 -0.11003 -0.14430 69  THR A C   
1066 O O   . THR A 69  ? 0.44266 0.54947 0.53572 -0.04311 -0.09057 -0.12639 69  THR A O   
1067 C CB  . THR A 69  ? 0.48422 0.59310 0.63309 -0.07302 -0.14317 -0.15591 69  THR A CB  
1068 O OG1 . THR A 69  ? 0.96529 1.05572 1.13535 -0.07666 -0.12484 -0.14209 69  THR A OG1 
1069 C CG2 . THR A 69  ? 0.36862 0.50031 0.55692 -0.08755 -0.16194 -0.15070 69  THR A CG2 
1077 N N   . GLY A 70  ? 0.36442 0.46570 0.41641 -0.03773 -0.11547 -0.16636 70  GLY A N   
1078 C CA  . GLY A 70  ? 0.37179 0.45880 0.39937 -0.02629 -0.09753 -0.16863 70  GLY A CA  
1079 C C   . GLY A 70  ? 0.49841 0.55438 0.54851 -0.03108 -0.09204 -0.17265 70  GLY A C   
1080 O O   . GLY A 70  ? 0.46988 0.50729 0.53893 -0.03974 -0.10712 -0.18793 70  GLY A O   
1084 N N   . MET A 71  ? 0.54904 0.59859 0.59818 -0.02594 -0.07182 -0.15782 71  MET A N   
1085 C CA  . MET A 71  ? 0.49950 0.52229 0.56851 -0.02907 -0.06501 -0.15607 71  MET A CA  
1086 C C   . MET A 71  ? 0.60180 0.61082 0.64678 -0.01525 -0.05730 -0.16954 71  MET A C   
1087 O O   . MET A 71  ? 0.67358 0.69903 0.68839 -0.00361 -0.05011 -0.17218 71  MET A O   
1088 C CB  . MET A 71  ? 0.59115 0.61877 0.67851 -0.03303 -0.04892 -0.12902 71  MET A CB  
1089 C CG  . MET A 71  ? 0.74141 0.77401 0.86595 -0.04752 -0.05422 -0.11645 71  MET A CG  
1090 S SD  . MET A 71  ? 0.85786 0.89930 0.99739 -0.04821 -0.03352 -0.08786 71  MET A SD  
1091 C CE  . MET A 71  ? 0.47785 0.48933 0.61980 -0.04727 -0.02537 -0.08665 71  MET A CE  
1101 N N   . ILE A 72  ? 0.52223 0.50224 0.58379 -0.01651 -0.05876 -0.17615 72  ILE A N   
1102 C CA  . ILE A 72  ? 0.50396 0.47033 0.54952 -0.00185 -0.05119 -0.18788 72  ILE A CA  
1103 C C   . ILE A 72  ? 0.33347 0.31085 0.37462 0.00338  -0.03107 -0.16586 72  ILE A C   
1104 O O   . ILE A 72  ? 0.50091 0.47569 0.56171 -0.00509 -0.02455 -0.14482 72  ILE A O   
1105 C CB  . ILE A 72  ? 0.54690 0.47566 0.61556 -0.00443 -0.06079 -0.19949 72  ILE A CB  
1106 C CG1 . ILE A 72  ? 0.57894 0.49372 0.64689 -0.00708 -0.08330 -0.22850 72  ILE A CG1 
1107 C CG2 . ILE A 72  ? 0.46131 0.37689 0.52075 0.01193  -0.05038 -0.20519 72  ILE A CG2 
1108 C CD1 . ILE A 72  ? 0.74683 0.63474 0.85442 -0.02527 -0.09859 -0.22522 72  ILE A CD1 
1120 N N   . LEU A 73  ? 0.50819 0.50016 0.52355 0.01729  -0.02151 -0.17079 73  LEU A N   
1121 C CA  . LEU A 73  ? 0.45734 0.46063 0.46898 0.02204  -0.00489 -0.15254 73  LEU A CA  
1122 C C   . LEU A 73  ? 0.45397 0.45000 0.46024 0.03670  0.00085  -0.16398 73  LEU A C   
1123 O O   . LEU A 73  ? 0.58290 0.58594 0.57042 0.04875  -0.00094 -0.18420 73  LEU A O   
1124 C CB  . LEU A 73  ? 0.62423 0.65802 0.61567 0.02331  0.00185  -0.14205 73  LEU A CB  
1125 C CG  . LEU A 73  ? 0.45114 0.49823 0.43876 0.02678  0.01658  -0.12459 73  LEU A CG  
1126 C CD1 . LEU A 73  ? 0.41157 0.44775 0.41856 0.01810  0.02043  -0.10640 73  LEU A CD1 
1127 C CD2 . LEU A 73  ? 0.42509 0.49972 0.39351 0.02759  0.02045  -0.11563 73  LEU A CD2 
1139 N N   . GLU A 74  ? 0.56029 0.54485 0.58227 0.03719  0.00769  -0.15122 74  GLU A N   
1140 C CA  . GLU A 74  ? 0.42691 0.40448 0.45009 0.05189  0.01232  -0.15951 74  GLU A CA  
1141 C C   . GLU A 74  ? 0.37711 0.36857 0.40419 0.05310  0.02458  -0.13850 74  GLU A C   
1142 O O   . GLU A 74  ? 0.52792 0.52426 0.55936 0.04183  0.02754  -0.11934 74  GLU A O   
1143 C CB  . GLU A 74  ? 0.55599 0.49622 0.60045 0.05221  0.00209  -0.16828 74  GLU A CB  
1144 C CG  . GLU A 74  ? 0.62251 0.54434 0.66594 0.05097  -0.01343 -0.19306 74  GLU A CG  
1145 C CD  . GLU A 74  ? 0.59540 0.47556 0.66456 0.04947  -0.02521 -0.19986 74  GLU A CD  
1146 O OE1 . GLU A 74  ? 0.77820 0.64536 0.86846 0.04296  -0.02210 -0.17803 74  GLU A OE1 
1147 O OE2 . GLU A 74  ? 0.50491 0.36794 0.57042 0.05346  -0.03733 -0.22081 74  GLU A OE2 
1154 N N   . GLU A 75  ? 0.51054 0.50938 0.53678 0.06787  0.03091  -0.14367 75  GLU A N   
1155 C CA  . GLU A 75  ? 0.50142 0.51590 0.53372 0.06960  0.04020  -0.12560 75  GLU A CA  
1156 C C   . GLU A 75  ? 0.42691 0.41619 0.47909 0.06740  0.03623  -0.11501 75  GLU A C   
1157 O O   . GLU A 75  ? 0.49214 0.46980 0.55538 0.07968  0.03488  -0.12050 75  GLU A O   
1158 C CB  . GLU A 75  ? 0.42268 0.46210 0.44978 0.08646  0.04878  -0.13364 75  GLU A CB  
1159 C CG  . GLU A 75  ? 0.65162 0.70411 0.69287 0.09002  0.05490  -0.11768 75  GLU A CG  
1160 C CD  . GLU A 75  ? 0.88211 0.97333 0.92010 0.10180  0.06589  -0.11878 75  GLU A CD  
1161 O OE1 . GLU A 75  ? 0.81647 0.92748 0.86568 0.09939  0.07041  -0.10221 75  GLU A OE1 
1162 O OE2 . GLU A 75  ? 0.54791 0.65040 0.57189 0.11175  0.06919  -0.13401 75  GLU A OE2 
1169 N N   . GLY A 76  ? 0.44433 0.42666 0.50079 0.05290  0.03466  -0.09865 76  GLY A N   
1170 C CA  . GLY A 76  ? 0.42765 0.39074 0.49928 0.04965  0.03196  -0.08466 76  GLY A CA  
1171 C C   . GLY A 76  ? 0.56137 0.49264 0.64773 0.04733  0.02262  -0.09106 76  GLY A C   
1172 O O   . GLY A 76  ? 0.41456 0.33692 0.49946 0.04662  0.01635  -0.10855 76  GLY A O   
1176 N N   . ALA A 77  ? 0.51482 0.42873 0.61605 0.04535  0.02038  -0.07551 77  ALA A N   
1177 C CA  . ALA A 77  ? 0.45788 0.33874 0.57900 0.04126  0.01092  -0.07517 77  ALA A CA  
1178 C C   . ALA A 77  ? 0.48631 0.34807 0.62079 0.05499  0.00747  -0.07286 77  ALA A C   
1179 O O   . ALA A 77  ? 0.59515 0.47352 0.72481 0.06501  0.01306  -0.06542 77  ALA A O   
1180 C CB  . ALA A 77  ? 0.48234 0.36037 0.61262 0.02429  0.01160  -0.05212 77  ALA A CB  
1186 N N   . PRO A 78  ? 0.51886 0.34500 0.67282 0.05582  -0.00326 -0.07883 78  PRO A N   
1187 C CA  . PRO A 78  ? 0.51343 0.31709 0.68399 0.06899  -0.00786 -0.07234 78  PRO A CA  
1188 C C   . PRO A 78  ? 0.43675 0.24841 0.61052 0.06331  -0.00367 -0.03905 78  PRO A C   
1189 O O   . PRO A 78  ? 0.44272 0.26275 0.61371 0.04662  -0.00024 -0.02066 78  PRO A O   
1190 C CB  . PRO A 78  ? 0.63476 0.39384 0.82825 0.06464  -0.02217 -0.08119 78  PRO A CB  
1191 C CG  . PRO A 78  ? 0.53095 0.29380 0.71519 0.05548  -0.02570 -0.10364 78  PRO A CG  
1192 C CD  . PRO A 78  ? 0.45192 0.25538 0.61598 0.04478  -0.01375 -0.09225 78  PRO A CD  
1200 N N   . GLU A 79  ? 0.64806 0.45998 0.82705 0.07886  -0.00405 -0.03177 79  GLU A N   
1201 C CA  . GLU A 79  ? 0.67657 0.49911 0.85457 0.07581  -0.00175 -0.00122 79  GLU A CA  
1202 C C   . GLU A 79  ? 0.61281 0.40917 0.80645 0.06182  -0.00701 0.02290  79  GLU A C   
1203 O O   . GLU A 79  ? 0.66969 0.42912 0.88591 0.06162  -0.01674 0.01942  79  GLU A O   
1204 C CB  . GLU A 79  ? 0.76588 0.59139 0.95172 0.09619  -0.00447 0.00212  79  GLU A CB  
1205 C CG  . GLU A 79  ? 0.63944 0.50334 0.81160 0.10678  0.00291  -0.01090 79  GLU A CG  
1206 C CD  . GLU A 79  ? 0.72963 0.59655 0.89907 0.11569  0.00587  -0.04256 79  GLU A CD  
1207 O OE1 . GLU A 79  ? 0.73562 0.57102 0.91401 0.11713  -0.00023 -0.05812 79  GLU A OE1 
1208 O OE2 . GLU A 79  ? 0.63941 0.54102 0.79753 0.12083  0.01368  -0.05150 79  GLU A OE2 
1215 N N   . GLY A 80  ? 0.63085 0.44709 0.81282 0.05009  -0.00065 0.04765  80  GLY A N   
1216 C CA  . GLY A 80  ? 0.56907 0.37107 0.76371 0.03548  -0.00204 0.07493  80  GLY A CA  
1217 C C   . GLY A 80  ? 0.50510 0.30835 0.70426 0.01675  0.00093  0.07175  80  GLY A C   
1218 O O   . GLY A 80  ? 0.62044 0.42115 0.83080 0.00266  0.00257  0.09727  80  GLY A O   
1222 N N   . THR A 81  ? 0.56281 0.37317 0.75476 0.01627  0.00170  0.04328  81  THR A N   
1223 C CA  . THR A 81  ? 0.70992 0.52503 0.90772 -0.00061 0.00289  0.03969  81  THR A CA  
1224 C C   . THR A 81  ? 0.47479 0.32340 0.65755 -0.00972 0.01540  0.05932  81  THR A C   
1225 O O   . THR A 81  ? 0.46683 0.34069 0.62422 -0.00232 0.02303  0.05620  81  THR A O   
1226 C CB  . THR A 81  ? 0.80258 0.62310 0.99039 0.00332  0.00078  0.00614  81  THR A CB  
1227 O OG1 . THR A 81  ? 0.58322 0.37342 0.78251 0.01396  -0.01043 -0.01525 81  THR A OG1 
1228 C CG2 . THR A 81  ? 0.45444 0.28357 0.64915 -0.01358 0.00031  0.00312  81  THR A CG2 
1236 N N   . VAL A 82  ? 0.50641 0.35572 0.70649 -0.02558 0.01723  0.07919  82  VAL A N   
1237 C CA  . VAL A 82  ? 0.52190 0.40548 0.70934 -0.03274 0.03039  0.09520  82  VAL A CA  
1238 C C   . VAL A 82  ? 0.49421 0.39376 0.67858 -0.03752 0.03207  0.07407  82  VAL A C   
1239 O O   . VAL A 82  ? 0.62768 0.51872 0.83570 -0.04916 0.02557  0.06910  82  VAL A O   
1240 C CB  . VAL A 82  ? 0.51986 0.40491 0.72889 -0.04683 0.03401  0.12856  82  VAL A CB  
1241 C CG1 . VAL A 82  ? 0.64251 0.56815 0.83511 -0.05010 0.04997  0.14288  82  VAL A CG1 
1242 C CG2 . VAL A 82  ? 0.40286 0.26883 0.61636 -0.04193 0.03015  0.15211  82  VAL A CG2 
1252 N N   . ALA A 83  ? 0.57196 0.49363 0.72881 -0.02886 0.03891  0.06206  83  ALA A N   
1253 C CA  . ALA A 83  ? 0.36227 0.29882 0.51363 -0.03082 0.03988  0.04345  83  ALA A CA  
1254 C C   . ALA A 83  ? 0.58290 0.54864 0.73017 -0.03582 0.05137  0.05634  83  ALA A C   
1255 O O   . ALA A 83  ? 0.46426 0.44229 0.60447 -0.03505 0.06028  0.07644  83  ALA A O   
1256 C CB  . ALA A 83  ? 0.50192 0.44276 0.62900 -0.01833 0.03939  0.02306  83  ALA A CB  
1262 N N   . THR A 84  ? 0.45742 0.43600 0.60838 -0.03937 0.05099  0.04419  84  THR A N   
1263 C CA  . THR A 84  ? 0.48239 0.49001 0.63032 -0.04042 0.06163  0.05160  84  THR A CA  
1264 C C   . THR A 84  ? 0.40331 0.41998 0.52520 -0.02973 0.06362  0.03497  84  THR A C   
1265 O O   . THR A 84  ? 0.33607 0.34587 0.45532 -0.02823 0.05579  0.01739  84  THR A O   
1266 C CB  . THR A 84  ? 0.44344 0.46152 0.62136 -0.05270 0.05862  0.05369  84  THR A CB  
1267 O OG1 . THR A 84  ? 0.51830 0.52332 0.72531 -0.06538 0.05388  0.06912  84  THR A OG1 
1268 C CG2 . THR A 84  ? 0.39131 0.44315 0.56984 -0.05131 0.07166  0.06401  84  THR A CG2 
1276 N N   . LEU A 85  ? 0.35556 0.38705 0.45777 -0.02233 0.07339  0.04085  85  LEU A N   
1277 C CA  . LEU A 85  ? 0.48318 0.52109 0.56368 -0.01334 0.07465  0.02729  85  LEU A CA  
1278 C C   . LEU A 85  ? 0.40723 0.46657 0.49480 -0.01261 0.08149  0.02860  85  LEU A C   
1279 O O   . LEU A 85  ? 0.38169 0.45804 0.46577 -0.00922 0.09217  0.03940  85  LEU A O   
1280 C CB  . LEU A 85  ? 0.58271 0.61968 0.63763 -0.00505 0.07776  0.02948  85  LEU A CB  
1281 C CG  . LEU A 85  ? 0.51881 0.55900 0.55252 0.00297  0.07759  0.01683  85  LEU A CG  
1282 C CD1 . LEU A 85  ? 0.36571 0.39697 0.40192 0.00195  0.06948  0.00303  85  LEU A CD1 
1283 C CD2 . LEU A 85  ? 0.45773 0.49549 0.46904 0.00885  0.07687  0.01862  85  LEU A CD2 
1295 N N   . LEU A 86  ? 0.33876 0.39984 0.43592 -0.01431 0.07547  0.01789  86  LEU A N   
1296 C CA  . LEU A 86  ? 0.54045 0.62306 0.65127 -0.01328 0.07982  0.01962  86  LEU A CA  
1297 C C   . LEU A 86  ? 0.39902 0.48555 0.48898 -0.00065 0.08393  0.01166  86  LEU A C   
1298 O O   . LEU A 86  ? 0.34452 0.42323 0.42758 0.00240  0.07680  0.00080  86  LEU A O   
1299 C CB  . LEU A 86  ? 0.31431 0.39747 0.44486 -0.02049 0.06889  0.01260  86  LEU A CB  
1300 C CG  . LEU A 86  ? 0.47889 0.55796 0.63601 -0.03416 0.06226  0.01822  86  LEU A CG  
1301 C CD1 . LEU A 86  ? 0.41065 0.46238 0.55859 -0.03631 0.05583  0.01348  86  LEU A CD1 
1302 C CD2 . LEU A 86  ? 0.38438 0.47125 0.56077 -0.04031 0.05068  0.01023  86  LEU A CD2 
1314 N N   . ILE A 87  ? 0.30996 0.40852 0.38958 0.00706  0.09514  0.01740  87  ILE A N   
1315 C CA  . ILE A 87  ? 0.43404 0.53159 0.49223 0.02022  0.09789  0.00733  87  ILE A CA  
1316 C C   . ILE A 87  ? 0.46428 0.58374 0.53639 0.02834  0.10493  0.00728  87  ILE A C   
1317 O O   . ILE A 87  ? 0.51408 0.65846 0.60280 0.02751  0.11524  0.01915  87  ILE A O   
1318 C CB  . ILE A 87  ? 0.49179 0.58775 0.52395 0.02651  0.10393  0.00916  87  ILE A CB  
1319 C CG1 . ILE A 87  ? 0.45616 0.52933 0.47414 0.02197  0.09376  0.00491  87  ILE A CG1 
1320 C CG2 . ILE A 87  ? 0.40034 0.50172 0.41461 0.04171  0.10919  -0.00143 87  ILE A CG2 
1321 C CD1 . ILE A 87  ? 0.70925 0.77822 0.69924 0.02876  0.09417  0.00231  87  ILE A CD1 
1333 N N   . LYS A 88  ? 0.43082 0.54237 0.49865 0.03647  0.09944  -0.00431 88  LYS A N   
1334 C CA  . LYS A 88  ? 0.31160 0.44093 0.39218 0.04815  0.10462  -0.00647 88  LYS A CA  
1335 C C   . LYS A 88  ? 0.42779 0.54548 0.48383 0.06421  0.10692  -0.01939 88  LYS A C   
1336 O O   . LYS A 88  ? 0.37386 0.46452 0.41238 0.06355  0.09694  -0.02854 88  LYS A O   
1337 C CB  . LYS A 88  ? 0.42740 0.55509 0.52692 0.04504  0.09342  -0.00822 88  LYS A CB  
1338 C CG  . LYS A 88  ? 0.40731 0.56585 0.53773 0.04870  0.09782  -0.00148 88  LYS A CG  
1339 C CD  . LYS A 88  ? 0.40364 0.56021 0.54892 0.04635  0.08393  -0.00306 88  LYS A CD  
1340 C CE  . LYS A 88  ? 0.38151 0.55603 0.55415 0.03143  0.07791  0.00520  88  LYS A CE  
1341 N NZ  . LYS A 88  ? 0.32364 0.50361 0.51031 0.03164  0.06413  0.00403  88  LYS A NZ  
1355 N N   . ARG A 89  ? 0.31132 0.44991 0.36713 0.07859  0.11954  -0.02067 89  ARG A N   
1356 C CA  . ARG A 89  ? 0.49434 0.61982 0.52496 0.09587  0.12072  -0.03694 89  ARG A CA  
1357 C C   . ARG A 89  ? 0.31355 0.43780 0.35833 0.11067  0.11819  -0.04583 89  ARG A C   
1358 O O   . ARG A 89  ? 0.37909 0.52546 0.45365 0.11086  0.12057  -0.03716 89  ARG A O   
1359 C CB  . ARG A 89  ? 0.51462 0.66015 0.52798 0.10356  0.13457  -0.03577 89  ARG A CB  
1360 C CG  . ARG A 89  ? 0.36704 0.50833 0.35947 0.09328  0.13515  -0.02825 89  ARG A CG  
1361 C CD  . ARG A 89  ? 0.50474 0.61360 0.46709 0.09586  0.12303  -0.04425 89  ARG A CD  
1362 N NE  . ARG A 89  ? 0.39082 0.48933 0.34398 0.08112  0.11652  -0.03571 89  ARG A NE  
1363 C CZ  . ARG A 89  ? 0.56042 0.67067 0.49492 0.08098  0.12275  -0.02760 89  ARG A CZ  
1364 N NH1 . ARG A 89  ? 0.49072 0.62258 0.41405 0.09024  0.13398  -0.02552 89  ARG A NH1 
1365 N NH2 . ARG A 89  ? 0.65399 0.75218 0.58340 0.06903  0.11454  -0.02028 89  ARG A NH2 
1379 N N   . PRO A 90  ? 0.56891 0.66583 0.59506 0.12302  0.11125  -0.06301 90  PRO A N   
1380 C CA  . PRO A 90  ? 0.53273 0.62221 0.57396 0.13848  0.10668  -0.07103 90  PRO A CA  
1381 C C   . PRO A 90  ? 0.51692 0.63949 0.57752 0.15026  0.11910  -0.06821 90  PRO A C   
1382 O O   . PRO A 90  ? 0.65975 0.78594 0.74382 0.16045  0.11576  -0.06832 90  PRO A O   
1383 C CB  . PRO A 90  ? 0.48823 0.54099 0.50265 0.14934  0.09811  -0.09162 90  PRO A CB  
1384 C CG  . PRO A 90  ? 0.45010 0.48636 0.44263 0.13183  0.09132  -0.09039 90  PRO A CG  
1385 C CD  . PRO A 90  ? 0.58707 0.65593 0.58061 0.12231  0.10426  -0.07555 90  PRO A CD  
1393 N N   . THR A 91  ? 0.46550 0.61177 0.51806 0.14758  0.13174  -0.06393 91  THR A N   
1394 C CA  . THR A 91  ? 0.50604 0.68751 0.57944 0.15430  0.14372  -0.05782 91  THR A CA  
1395 C C   . THR A 91  ? 0.46273 0.67467 0.57334 0.14239  0.14520  -0.03868 91  THR A C   
1396 O O   . THR A 91  ? 0.30856 0.55230 0.44322 0.14643  0.15328  -0.03200 91  THR A O   
1397 C CB  . THR A 91  ? 0.47695 0.67596 0.52925 0.15420  0.15666  -0.05592 91  THR A CB  
1398 O OG1 . THR A 91  ? 0.54444 0.75360 0.59507 0.13548  0.15901  -0.03924 91  THR A OG1 
1399 C CG2 . THR A 91  ? 0.49219 0.66279 0.50573 0.16471  0.15314  -0.07557 91  THR A CG2 
1407 N N   . GLY A 92  ? 0.27327 0.47706 0.38981 0.12762  0.13717  -0.03014 92  GLY A N   
1408 C CA  . GLY A 92  ? 0.27109 0.50123 0.42136 0.11319  0.13639  -0.01285 92  GLY A CA  
1409 C C   . GLY A 92  ? 0.29026 0.53851 0.44302 0.09624  0.14441  0.00185  92  GLY A C   
1410 O O   . GLY A 92  ? 0.34545 0.61066 0.52725 0.08097  0.14134  0.01568  92  GLY A O   
1414 N N   . GLU A 93  ? 0.30212 0.54626 0.42642 0.09804  0.15288  -0.00001 93  GLU A N   
1415 C CA  . GLU A 93  ? 0.29736 0.55762 0.42460 0.08301  0.16007  0.01724  93  GLU A CA  
1416 C C   . GLU A 93  ? 0.34073 0.58491 0.47233 0.06537  0.15174  0.02534  93  GLU A C   
1417 O O   . GLU A 93  ? 0.36465 0.58135 0.47931 0.06703  0.14390  0.01541  93  GLU A O   
1418 C CB  . GLU A 93  ? 0.38923 0.64725 0.48126 0.09010  0.16908  0.01436  93  GLU A CB  
1419 C CG  . GLU A 93  ? 0.66149 0.94840 0.76285 0.08096  0.18041  0.03490  93  GLU A CG  
1420 C CD  . GLU A 93  ? 0.55817 0.84216 0.62231 0.08556  0.18716  0.03585  93  GLU A CD  
1421 O OE1 . GLU A 93  ? 0.71858 0.99988 0.75683 0.10272  0.19081  0.02002  93  GLU A OE1 
1422 O OE2 . GLU A 93  ? 0.88951 1.17324 0.95081 0.07227  0.18771  0.05257  93  GLU A OE2 
1429 N N   . LEU A 94  ? 0.44926 0.70960 0.60560 0.04833  0.15314  0.04352  94  LEU A N   
1430 C CA  . LEU A 94  ? 0.48732 0.73215 0.65332 0.03073  0.14527  0.05168  94  LEU A CA  
1431 C C   . LEU A 94  ? 0.22983 0.46661 0.37477 0.02492  0.15077  0.06204  94  LEU A C   
1432 O O   . LEU A 94  ? 0.42285 0.67879 0.56918 0.02326  0.15963  0.07483  94  LEU A O   
1433 C CB  . LEU A 94  ? 0.41020 0.67234 0.62059 0.01412  0.13892  0.06368  94  LEU A CB  
1434 C CG  . LEU A 94  ? 0.41074 0.68701 0.64466 0.02014  0.13202  0.05605  94  LEU A CG  
1435 C CD1 . LEU A 94  ? 0.40022 0.68945 0.67629 0.00094  0.12048  0.06538  94  LEU A CD1 
1436 C CD2 . LEU A 94  ? 0.38915 0.63228 0.59646 0.02918  0.11976  0.03656  94  LEU A CD2 
1448 N N   . MET A 95  ? 0.39138 0.59715 0.51477 0.02186  0.14286  0.05590  95  MET A N   
1449 C CA  . MET A 95  ? 0.51497 0.71185 0.61392 0.02054  0.14694  0.06420  95  MET A CA  
1450 C C   . MET A 95  ? 0.38302 0.55031 0.48788 0.00520  0.13285  0.06673  95  MET A C   
1451 O O   . MET A 95  ? 0.37274 0.51247 0.45622 0.00740  0.12259  0.05329  95  MET A O   
1452 C CB  . MET A 95  ? 0.67588 0.86025 0.73323 0.03681  0.14764  0.04781  95  MET A CB  
1453 C CG  . MET A 95  ? 0.68654 0.89067 0.72866 0.05186  0.15737  0.04195  95  MET A CG  
1454 S SD  . MET A 95  ? 1.10813 1.31641 1.11325 0.05642  0.16346  0.04912  95  MET A SD  
1455 C CE  . MET A 95  ? 0.62525 0.80058 0.59581 0.06201  0.15175  0.03128  95  MET A CE  
1465 N N   . PRO A 96  ? 0.45579 0.62828 0.59149 -0.01019 0.13171  0.08359  96  PRO A N   
1466 C CA  . PRO A 96  ? 0.35444 0.49613 0.49548 -0.02227 0.11838  0.08459  96  PRO A CA  
1467 C C   . PRO A 96  ? 0.44914 0.58216 0.56916 -0.02055 0.12234  0.09724  96  PRO A C   
1468 O O   . PRO A 96  ? 0.50204 0.65632 0.62520 -0.02198 0.13451  0.11899  96  PRO A O   
1469 C CB  . PRO A 96  ? 0.47176 0.62179 0.65610 -0.03924 0.11473  0.09795  96  PRO A CB  
1470 C CG  . PRO A 96  ? 0.39253 0.58521 0.59385 -0.03757 0.13125  0.11446  96  PRO A CG  
1471 C CD  . PRO A 96  ? 0.40214 0.60973 0.56975 -0.01695 0.14336  0.10453  96  PRO A CD  
1479 N N   . LEU A 97  ? 0.56499 0.67014 0.66437 -0.01715 0.11218  0.08537  97  LEU A N   
1480 C CA  . LEU A 97  ? 0.57611 0.67260 0.65443 -0.01374 0.11285  0.09557  97  LEU A CA  
1481 C C   . LEU A 97  ? 0.42947 0.49752 0.52296 -0.02238 0.10069  0.09936  97  LEU A C   
1482 O O   . LEU A 97  ? 0.40719 0.45596 0.50810 -0.02427 0.08959  0.08211  97  LEU A O   
1483 C CB  . LEU A 97  ? 0.52371 0.61486 0.56573 -0.00045 0.11061  0.07868  97  LEU A CB  
1484 C CG  . LEU A 97  ? 0.53242 0.64675 0.55206 0.01164  0.12183  0.07404  97  LEU A CG  
1485 C CD1 . LEU A 97  ? 0.64782 0.74915 0.63641 0.02175  0.11444  0.05450  97  LEU A CD1 
1486 C CD2 . LEU A 97  ? 0.44502 0.58378 0.45560 0.01400  0.13525  0.09634  97  LEU A CD2 
1498 N N   . ALA A 98  ? 0.51371 0.57981 0.61088 -0.02620 0.10298  0.12236  98  ALA A N   
1499 C CA  . ALA A 98  ? 0.34726 0.38371 0.45976 -0.03194 0.09128  0.12773  98  ALA A CA  
1500 C C   . ALA A 98  ? 0.39212 0.41516 0.47774 -0.02036 0.08494  0.11923  98  ALA A C   
1501 O O   . ALA A 98  ? 0.51023 0.54771 0.56882 -0.01223 0.09048  0.12646  98  ALA A O   
1502 C CB  . ALA A 98  ? 0.50474 0.54374 0.63790 -0.04205 0.09545  0.16021  98  ALA A CB  
1508 N N   . ALA A 99  ? 0.35505 0.35342 0.44811 -0.01898 0.07305  0.10297  99  ALA A N   
1509 C CA  . ALA A 99  ? 0.48127 0.47049 0.55578 -0.00829 0.06649  0.09446  99  ALA A CA  
1510 C C   . ALA A 99  ? 0.56624 0.52734 0.66124 -0.00816 0.05567  0.09355  99  ALA A C   
1511 O O   . ALA A 99  ? 0.65530 0.60197 0.76742 -0.01171 0.04994  0.07810  99  ALA A O   
1512 C CB  . ALA A 99  ? 0.35246 0.34799 0.41068 -0.00242 0.06515  0.06964  99  ALA A CB  
1518 N N   . ARG A 100 ? 0.46052 0.41391 0.55306 -0.00270 0.05202  0.10932  100 ARG A N   
1519 C CA  . ARG A 100 ? 0.48864 0.41402 0.60024 0.00166  0.04121  0.10757  100 ARG A CA  
1520 C C   . ARG A 100 ? 0.48204 0.40868 0.58295 0.01361  0.03646  0.08427  100 ARG A C   
1521 O O   . ARG A 100 ? 0.40547 0.34723 0.48755 0.02132  0.03647  0.08649  100 ARG A O   
1522 C CB  . ARG A 100 ? 0.42549 0.34349 0.54070 0.00409  0.03856  0.13641  100 ARG A CB  
1523 C CG  . ARG A 100 ? 0.64723 0.53355 0.78449 0.01146  0.02649  0.13513  100 ARG A CG  
1524 C CD  . ARG A 100 ? 0.55449 0.42997 0.70026 0.01237  0.02273  0.16864  100 ARG A CD  
1525 N NE  . ARG A 100 ? 0.70360 0.56215 0.87563 -0.00255 0.02295  0.18934  100 ARG A NE  
1526 C CZ  . ARG A 100 ? 0.70829 0.58431 0.87701 -0.01283 0.03169  0.22015  100 ARG A CZ  
1527 N NH1 . ARG A 100 ? 0.81557 0.72541 0.95126 -0.00814 0.04088  0.23165  100 ARG A NH1 
1528 N NH2 . ARG A 100 ? 0.69573 0.55611 0.89547 -0.02822 0.03087  0.23983  100 ARG A NH2 
1542 N N   . MET A 101 ? 0.49280 0.40630 0.60583 0.01482  0.03211  0.06230  101 MET A N   
1543 C CA  . MET A 101 ? 0.41122 0.33254 0.51510 0.02512  0.03041  0.04119  101 MET A CA  
1544 C C   . MET A 101 ? 0.66081 0.57337 0.77221 0.03854  0.02396  0.04404  101 MET A C   
1545 O O   . MET A 101 ? 0.40448 0.29246 0.53482 0.04130  0.01787  0.05214  101 MET A O   
1546 C CB  . MET A 101 ? 0.39459 0.30871 0.50544 0.02370  0.02864  0.01757  101 MET A CB  
1547 C CG  . MET A 101 ? 0.51340 0.44063 0.61732 0.01265  0.03371  0.01287  101 MET A CG  
1548 S SD  . MET A 101 ? 0.54618 0.50197 0.62546 0.01121  0.04231  0.02039  101 MET A SD  
1549 C CE  . MET A 101 ? 0.47593 0.44392 0.54320 0.02050  0.04098  0.00350  101 MET A CE  
1559 N N   . GLY A 102 ? 0.43214 0.36498 0.53181 0.04682  0.02440  0.03792  102 GLY A N   
1560 C CA  . GLY A 102 ? 0.31207 0.24499 0.42022 0.06061  0.01848  0.04194  102 GLY A CA  
1561 C C   . GLY A 102 ? 0.41153 0.35133 0.52740 0.07222  0.01827  0.02057  102 GLY A C   
1562 O O   . GLY A 102 ? 0.46669 0.39601 0.58763 0.07269  0.01975  0.00256  102 GLY A O   
1566 N N   . THR A 103 ? 0.41997 0.38089 0.53670 0.08182  0.01629  0.02267  103 THR A N   
1567 C CA  . THR A 103 ? 0.44251 0.41580 0.57068 0.09538  0.01752  0.00623  103 THR A CA  
1568 C C   . THR A 103 ? 0.39026 0.38594 0.50654 0.08892  0.02504  -0.00867 103 THR A C   
1569 O O   . THR A 103 ? 0.36848 0.37633 0.46944 0.07617  0.02704  -0.00386 103 THR A O   
1570 C CB  . THR A 103 ? 0.59232 0.58621 0.73074 0.10712  0.01247  0.01640  103 THR A CB  
1571 O OG1 . THR A 103 ? 0.62015 0.64130 0.74444 0.09719  0.01213  0.02344  103 THR A OG1 
1572 C CG2 . THR A 103 ? 0.65950 0.63245 0.80783 0.11340  0.00380  0.03581  103 THR A CG2 
1580 N N   . HIS A 104 ? 0.50776 0.50818 0.63061 0.09897  0.02903  -0.02680 104 HIS A N   
1581 C CA  . HIS A 104 ? 0.34221 0.36850 0.45556 0.09541  0.03658  -0.03796 104 HIS A CA  
1582 C C   . HIS A 104 ? 0.47534 0.53734 0.59829 0.10193  0.03842  -0.03284 104 HIS A C   
1583 O O   . HIS A 104 ? 0.26035 0.32852 0.40090 0.11764  0.03647  -0.03220 104 HIS A O   
1584 C CB  . HIS A 104 ? 0.41762 0.43730 0.53013 0.10423  0.04047  -0.05959 104 HIS A CB  
1585 C CG  . HIS A 104 ? 0.52805 0.51350 0.63622 0.09738  0.03600  -0.06661 104 HIS A CG  
1586 N ND1 . HIS A 104 ? 0.61879 0.60237 0.71576 0.09475  0.03791  -0.08379 104 HIS A ND1 
1587 C CD2 . HIS A 104 ? 0.75443 0.70861 0.87017 0.09199  0.02893  -0.05746 104 HIS A CD2 
1588 C CE1 . HIS A 104 ? 0.65287 0.60543 0.75273 0.08723  0.03103  -0.08629 104 HIS A CE1 
1589 N NE2 . HIS A 104 ? 0.61390 0.54835 0.72635 0.08484  0.02630  -0.06948 104 HIS A NE2 
1597 N N   . ALA A 105 ? 0.34597 0.43166 0.46079 0.08994  0.04132  -0.02861 105 ALA A N   
1598 C CA  . ALA A 105 ? 0.21914 0.34068 0.34786 0.09275  0.04160  -0.02183 105 ALA A CA  
1599 C C   . ALA A 105 ? 0.38107 0.52412 0.50254 0.07774  0.04508  -0.01907 105 ALA A C   
1600 O O   . ALA A 105 ? 0.35121 0.47874 0.45538 0.06469  0.04471  -0.01940 105 ALA A O   
1601 C CB  . ALA A 105 ? 0.44421 0.56635 0.58074 0.09284  0.03095  -0.00694 105 ALA A CB  
1607 N N   . THR A 106 ? 0.35058 0.53073 0.48884 0.08021  0.04835  -0.01502 106 THR A N   
1608 C CA  . THR A 106 ? 0.36903 0.57166 0.50929 0.06408  0.04784  -0.00625 106 THR A CA  
1609 C C   . THR A 106 ? 0.31404 0.51306 0.45716 0.05426  0.03412  0.00409  106 THR A C   
1610 O O   . THR A 106 ? 0.48708 0.70399 0.64874 0.06086  0.02790  0.01045  106 THR A O   
1611 C CB  . THR A 106 ? 0.37625 0.62396 0.53816 0.06957  0.05645  -0.00280 106 THR A CB  
1612 O OG1 . THR A 106 ? 0.34935 0.60205 0.50316 0.08143  0.06941  -0.01472 106 THR A OG1 
1613 C CG2 . THR A 106 ? 0.45755 0.72685 0.62616 0.05010  0.05474  0.00950  106 THR A CG2 
1621 N N   . MET A 107 ? 0.38838 0.56583 0.51276 0.04003  0.02869  0.00481  107 MET A N   
1622 C CA  . MET A 107 ? 0.33329 0.50422 0.45289 0.03177  0.01511  0.01063  107 MET A CA  
1623 C C   . MET A 107 ? 0.43109 0.61337 0.55510 0.01493  0.00905  0.01415  107 MET A C   
1624 O O   . MET A 107 ? 0.42611 0.60971 0.54899 0.00753  0.01588  0.01334  107 MET A O   
1625 C CB  . MET A 107 ? 0.27343 0.40988 0.36707 0.03083  0.01321  0.00736  107 MET A CB  
1626 C CG  . MET A 107 ? 0.46836 0.58907 0.56054 0.04424  0.01702  0.00683  107 MET A CG  
1627 S SD  . MET A 107 ? 0.54781 0.63404 0.61516 0.04049  0.01958  0.00519  107 MET A SD  
1628 C CE  . MET A 107 ? 0.40920 0.49094 0.47303 0.03547  0.02988  -0.00562 107 MET A CE  
1638 N N   . LYS A 108 ? 0.40797 0.59741 0.53742 0.00863  -0.00555 0.01855  108 LYS A N   
1639 C CA  . LYS A 108 ? 0.47654 0.66842 0.60989 -0.00882 -0.01604 0.01997  108 LYS A CA  
1640 C C   . LYS A 108 ? 0.38895 0.54702 0.49203 -0.01331 -0.02398 0.01169  108 LYS A C   
1641 O O   . LYS A 108 ? 0.35552 0.50541 0.44358 -0.00708 -0.03134 0.01011  108 LYS A O   
1642 C CB  . LYS A 108 ? 0.23887 0.46073 0.39847 -0.01424 -0.03009 0.02752  108 LYS A CB  
1643 C CG  . LYS A 108 ? 0.51462 0.77241 0.70259 -0.00175 -0.02372 0.03521  108 LYS A CG  
1644 C CD  . LYS A 108 ? 0.52520 0.80938 0.73367 -0.00236 -0.00789 0.04014  108 LYS A CD  
1645 C CE  . LYS A 108 ? 0.84706 1.16482 1.07930 0.01617  0.00121  0.04371  108 LYS A CE  
1646 N NZ  . LYS A 108 ? 0.46051 0.76107 0.67591 0.03439  0.01646  0.03400  108 LYS A NZ  
1660 N N   . ILE A 109 ? 0.35408 0.49457 0.44813 -0.02268 -0.02213 0.00733  109 ILE A N   
1661 C CA  . ILE A 109 ? 0.41874 0.52894 0.48553 -0.02479 -0.02782 -0.00238 109 ILE A CA  
1662 C C   . ILE A 109 ? 0.58121 0.68417 0.65527 -0.04005 -0.04001 -0.00489 109 ILE A C   
1663 O O   . ILE A 109 ? 0.41376 0.51926 0.50247 -0.04813 -0.03504 0.00065  109 ILE A O   
1664 C CB  . ILE A 109 ? 0.30723 0.39787 0.35650 -0.01807 -0.01347 -0.00651 109 ILE A CB  
1665 C CG1 . ILE A 109 ? 0.40448 0.49648 0.44764 -0.00488 -0.00523 -0.00439 109 ILE A CG1 
1666 C CG2 . ILE A 109 ? 0.31049 0.37493 0.33646 -0.01969 -0.01765 -0.01622 109 ILE A CG2 
1667 C CD1 . ILE A 109 ? 0.43378 0.51552 0.47213 0.00021  0.00875  -0.00631 109 ILE A CD1 
1679 N N   . GLN A 110 ? 0.39459 0.48843 0.45854 -0.04402 -0.05711 -0.01274 110 GLN A N   
1680 C CA  . GLN A 110 ? 0.39214 0.47426 0.46450 -0.05908 -0.07344 -0.01779 110 GLN A CA  
1681 C C   . GLN A 110 ? 0.38398 0.48930 0.49505 -0.07315 -0.07395 -0.00324 110 GLN A C   
1682 O O   . GLN A 110 ? 0.50435 0.59793 0.62662 -0.08457 -0.07503 0.00014  110 GLN A O   
1683 C CB  . GLN A 110 ? 0.47722 0.52442 0.52902 -0.05831 -0.07128 -0.02893 110 GLN A CB  
1684 C CG  . GLN A 110 ? 0.58471 0.61604 0.60024 -0.04311 -0.06594 -0.04073 110 GLN A CG  
1685 C CD  . GLN A 110 ? 0.64043 0.64298 0.63408 -0.04283 -0.07834 -0.05894 110 GLN A CD  
1686 O OE1 . GLN A 110 ? 0.84327 0.82390 0.82916 -0.03972 -0.07241 -0.06522 110 GLN A OE1 
1687 N NE2 . GLN A 110 ? 0.88032 0.88335 0.86337 -0.04456 -0.09657 -0.06875 110 GLN A NE2 
1696 N N   . GLY A 111 ? 0.49582 0.63671 0.62898 -0.07139 -0.07252 0.00733  111 GLY A N   
1697 C CA  . GLY A 111 ? 0.23872 0.41197 0.41139 -0.08345 -0.07181 0.02306  111 GLY A CA  
1698 C C   . GLY A 111 ? 0.45173 0.64100 0.63340 -0.07906 -0.04947 0.03420  111 GLY A C   
1699 O O   . GLY A 111 ? 0.42322 0.64917 0.63678 -0.08499 -0.04453 0.04902  111 GLY A O   
1703 N N   . ARG A 112 ? 0.44882 0.61540 0.60393 -0.06874 -0.03604 0.02775  112 ARG A N   
1704 C CA  . ARG A 112 ? 0.28764 0.46762 0.44598 -0.06422 -0.01700 0.03578  112 ARG A CA  
1705 C C   . ARG A 112 ? 0.43606 0.62890 0.58625 -0.04503 -0.00344 0.03174  112 ARG A C   
1706 O O   . ARG A 112 ? 0.43706 0.61651 0.57207 -0.03498 -0.00702 0.02290  112 ARG A O   
1707 C CB  . ARG A 112 ? 0.36754 0.51538 0.50524 -0.06599 -0.01313 0.03168  112 ARG A CB  
1708 C CG  . ARG A 112 ? 0.59737 0.75728 0.75068 -0.07680 -0.00699 0.04715  112 ARG A CG  
1709 C CD  . ARG A 112 ? 0.64510 0.77042 0.78144 -0.07948 -0.00819 0.04439  112 ARG A CD  
1710 N NE  . ARG A 112 ? 0.61865 0.71719 0.76210 -0.09314 -0.02639 0.04259  112 ARG A NE  
1711 C CZ  . ARG A 112 ? 0.75875 0.83366 0.90405 -0.10143 -0.03109 0.04803  112 ARG A CZ  
1712 N NH1 . ARG A 112 ? 0.80501 0.88276 0.94473 -0.09820 -0.01903 0.05788  112 ARG A NH1 
1713 N NH2 . ARG A 112 ? 0.78425 0.83108 0.93724 -0.11269 -0.04986 0.04309  112 ARG A NH2 
1727 N N   . THR A 113 ? 0.52501 0.74358 0.68501 -0.03968 0.01183  0.03860  113 THR A N   
1728 C CA  . THR A 113 ? 0.54158 0.77125 0.69677 -0.02067 0.02401  0.03276  113 THR A CA  
1729 C C   . THR A 113 ? 0.49355 0.69715 0.62157 -0.01297 0.03310  0.02301  113 THR A C   
1730 O O   . THR A 113 ? 0.31746 0.51948 0.43925 -0.01866 0.03874  0.02643  113 THR A O   
1731 C CB  . THR A 113 ? 0.40285 0.67846 0.58270 -0.01612 0.03565  0.04237  113 THR A CB  
1732 O OG1 . THR A 113 ? 0.70164 1.00543 0.91068 -0.01938 0.02697  0.05035  113 THR A OG1 
1733 C CG2 . THR A 113 ? 0.57397 0.85427 0.74388 0.00519  0.04931  0.03210  113 THR A CG2 
1741 N N   . VAL A 114 ? 0.40880 0.59367 0.52297 -0.00061 0.03359  0.01276  114 VAL A N   
1742 C CA  . VAL A 114 ? 0.39318 0.55135 0.48493 0.00449  0.03884  0.00348  114 VAL A CA  
1743 C C   . VAL A 114 ? 0.27857 0.43722 0.36964 0.02076  0.04566  -0.00442 114 VAL A C   
1744 O O   . VAL A 114 ? 0.38423 0.54001 0.48116 0.02831  0.04127  -0.00475 114 VAL A O   
1745 C CB  . VAL A 114 ? 0.51676 0.64366 0.59192 0.00008  0.03041  -0.00045 114 VAL A CB  
1746 C CG1 . VAL A 114 ? 0.43733 0.54262 0.49546 0.00446  0.03626  -0.00787 114 VAL A CG1 
1747 C CG2 . VAL A 114 ? 0.40672 0.52773 0.48228 -0.01386 0.02163  0.00346  114 VAL A CG2 
1757 N N   . GLY A 115 ? 0.34942 0.50905 0.43247 0.02649  0.05466  -0.01121 115 GLY A N   
1758 C CA  . GLY A 115 ? 0.32045 0.46983 0.39990 0.04097  0.05847  -0.02288 115 GLY A CA  
1759 C C   . GLY A 115 ? 0.39639 0.51177 0.46107 0.03829  0.05473  -0.02861 115 GLY A C   
1760 O O   . GLY A 115 ? 0.39424 0.50084 0.44738 0.02962  0.05461  -0.02852 115 GLY A O   
1764 N N   . GLY A 116 ? 0.35670 0.45430 0.42452 0.04586  0.05152  -0.03164 116 GLY A N   
1765 C CA  . GLY A 116 ? 0.37351 0.44288 0.43219 0.04185  0.04846  -0.03320 116 GLY A CA  
1766 C C   . GLY A 116 ? 0.28384 0.33641 0.35037 0.04957  0.04466  -0.03140 116 GLY A C   
1767 O O   . GLY A 116 ? 0.39876 0.45692 0.47740 0.06153  0.04468  -0.03410 116 GLY A O   
1771 N N   . GLN A 117 ? 0.41239 0.44562 0.47321 0.04340  0.04182  -0.02531 117 GLN A N   
1772 C CA  . GLN A 117 ? 0.40573 0.42053 0.47394 0.04820  0.03810  -0.01891 117 GLN A CA  
1773 C C   . GLN A 117 ? 0.44659 0.45835 0.50521 0.04123  0.03590  -0.00484 117 GLN A C   
1774 O O   . GLN A 117 ? 0.20981 0.22024 0.25730 0.03255  0.03850  -0.00434 117 GLN A O   
1775 C CB  . GLN A 117 ? 0.50333 0.49584 0.57654 0.04796  0.03796  -0.02661 117 GLN A CB  
1776 C CG  . GLN A 117 ? 0.42966 0.39927 0.51541 0.05181  0.03315  -0.01817 117 GLN A CG  
1777 C CD  . GLN A 117 ? 0.60652 0.55236 0.70236 0.05152  0.03020  -0.02921 117 GLN A CD  
1778 O OE1 . GLN A 117 ? 0.49434 0.44179 0.58453 0.04554  0.03148  -0.04079 117 GLN A OE1 
1779 N NE2 . GLN A 117 ? 0.32703 0.24952 0.43892 0.05794  0.02438  -0.02567 117 GLN A NE2 
1788 N N   . MET A 118 ? 0.33265 0.34541 0.39473 0.04669  0.03105  0.00633  118 MET A N   
1789 C CA  . MET A 118 ? 0.35018 0.36189 0.39907 0.04223  0.02891  0.01999  118 MET A CA  
1790 C C   . MET A 118 ? 0.47108 0.46412 0.52132 0.03841  0.03203  0.02837  118 MET A C   
1791 O O   . MET A 118 ? 0.35885 0.33511 0.42494 0.04083  0.03155  0.02658  118 MET A O   
1792 C CB  . MET A 118 ? 0.36792 0.38812 0.41933 0.04969  0.02118  0.03132  118 MET A CB  
1793 C CG  . MET A 118 ? 0.56295 0.60583 0.61971 0.05215  0.01679  0.02530  118 MET A CG  
1794 S SD  . MET A 118 ? 0.65136 0.70748 0.71956 0.06317  0.00580  0.03821  118 MET A SD  
1795 C CE  . MET A 118 ? 0.65789 0.71526 0.69844 0.05727  -0.00093 0.05110  118 MET A CE  
1805 N N   . GLY A 119 ? 0.31078 0.30775 0.34531 0.03238  0.03505  0.03705  119 GLY A N   
1806 C CA  . GLY A 119 ? 0.31527 0.30193 0.35288 0.02749  0.03936  0.04987  119 GLY A CA  
1807 C C   . GLY A 119 ? 0.27397 0.27161 0.29233 0.02757  0.04088  0.06621  119 GLY A C   
1808 O O   . GLY A 119 ? 0.41447 0.42588 0.41397 0.03050  0.03780  0.06270  119 GLY A O   
1812 N N   . MET A 120 ? 0.40896 0.40119 0.43231 0.02396  0.04504  0.08462  120 MET A N   
1813 C CA  . MET A 120 ? 0.42365 0.42987 0.42667 0.02469  0.04879  0.10332  120 MET A CA  
1814 C C   . MET A 120 ? 0.40617 0.41884 0.41137 0.01684  0.06051  0.11087  120 MET A C   
1815 O O   . MET A 120 ? 0.51738 0.51763 0.54775 0.00961  0.06229  0.11933  120 MET A O   
1816 C CB  . MET A 120 ? 0.56335 0.56255 0.57212 0.02889  0.04284  0.12674  120 MET A CB  
1817 C CG  . MET A 120 ? 0.86856 0.88603 0.85190 0.03070  0.04646  0.14875  120 MET A CG  
1818 S SD  . MET A 120 ? 1.14047 1.14690 1.13640 0.03296  0.04093  0.18430  120 MET A SD  
1819 C CE  . MET A 120 ? 0.86768 0.90385 0.82913 0.03240  0.05148  0.20938  120 MET A CE  
1829 N N   . LEU A 121 ? 0.49825 0.53065 0.47944 0.01861  0.06771  0.10666  121 LEU A N   
1830 C CA  . LEU A 121 ? 0.44678 0.49282 0.43043 0.01365  0.08065  0.11553  121 LEU A CA  
1831 C C   . LEU A 121 ? 0.41279 0.46612 0.39833 0.01118  0.08598  0.14713  121 LEU A C   
1832 O O   . LEU A 121 ? 0.58367 0.64351 0.54794 0.01763  0.08278  0.15966  121 LEU A O   
1833 C CB  . LEU A 121 ? 0.38189 0.44720 0.33786 0.02006  0.08709  0.10170  121 LEU A CB  
1834 C CG  . LEU A 121 ? 0.59264 0.65025 0.55072 0.02070  0.08276  0.07449  121 LEU A CG  
1835 C CD1 . LEU A 121 ? 0.38032 0.45112 0.31068 0.02878  0.08640  0.06056  121 LEU A CD1 
1836 C CD2 . LEU A 121 ? 0.55787 0.61007 0.54511 0.01277  0.08626  0.07099  121 LEU A CD2 
1848 N N   . LEU A 122 ? 0.43479 0.48788 0.44741 0.00095  0.09288  0.16169  122 LEU A N   
1849 C CA  . LEU A 122 ? 0.52911 0.58722 0.55148 -0.00469 0.09778  0.19618  122 LEU A CA  
1850 C C   . LEU A 122 ? 0.52810 0.62268 0.53597 -0.00449 0.11534  0.21147  122 LEU A C   
1851 O O   . LEU A 122 ? 0.62666 0.73449 0.65130 -0.01032 0.12459  0.20762  122 LEU A O   
1852 C CB  . LEU A 122 ? 0.55094 0.58472 0.61750 -0.01808 0.09262  0.20524  122 LEU A CB  
1853 C CG  . LEU A 122 ? 0.73374 0.73130 0.81612 -0.01603 0.07631  0.19033  122 LEU A CG  
1854 C CD1 . LEU A 122 ? 0.71084 0.68244 0.83535 -0.02902 0.07023  0.19934  122 LEU A CD1 
1855 C CD2 . LEU A 122 ? 0.49958 0.49029 0.56506 -0.00525 0.06842  0.20037  122 LEU A CD2 
1867 N N   . GLY A 133 ? 0.68849 0.82957 0.56935 0.05746  0.12869  0.05114  133 GLY A N   
1868 C CA  . GLY A 133 ? 0.49089 0.60741 0.35770 0.05864  0.11160  0.03074  133 GLY A CA  
1869 C C   . GLY A 133 ? 0.60761 0.70642 0.49328 0.05622  0.10544  0.01207  133 GLY A C   
1870 O O   . GLY A 133 ? 0.59538 0.70264 0.49855 0.05750  0.11429  0.01110  133 GLY A O   
1874 N N   . THR A 134 ? 0.42376 0.50090 0.30767 0.05250  0.09015  -0.00047 134 THR A N   
1875 C CA  . THR A 134 ? 0.41461 0.47511 0.31370 0.04968  0.08322  -0.01540 134 THR A CA  
1876 C C   . THR A 134 ? 0.60628 0.65494 0.48364 0.05735  0.07410  -0.03634 134 THR A C   
1877 O O   . THR A 134 ? 0.68655 0.73651 0.53745 0.06236  0.06862  -0.04152 134 THR A O   
1878 C CB  . THR A 134 ? 0.37272 0.41960 0.29172 0.03819  0.07361  -0.01157 134 THR A CB  
1879 O OG1 . THR A 134 ? 0.62571 0.66793 0.53163 0.03707  0.06322  -0.01153 134 THR A OG1 
1880 C CG2 . THR A 134 ? 0.54420 0.59688 0.48587 0.03119  0.08019  0.00494  134 THR A CG2 
1888 N N   . THR A 135 ? 0.58943 0.62531 0.47870 0.05809  0.07086  -0.04826 135 THR A N   
1889 C CA  . THR A 135 ? 0.67594 0.69543 0.54980 0.06544  0.06152  -0.06875 135 THR A CA  
1890 C C   . THR A 135 ? 0.42441 0.42271 0.31829 0.05676  0.05007  -0.07351 135 THR A C   
1891 O O   . THR A 135 ? 0.49763 0.49833 0.41399 0.04762  0.05184  -0.06212 135 THR A O   
1892 C CB  . THR A 135 ? 0.65729 0.68502 0.52202 0.08160  0.07241  -0.07862 135 THR A CB  
1893 O OG1 . THR A 135 ? 0.78599 0.81093 0.67738 0.08140  0.07600  -0.07715 135 THR A OG1 
1894 C CG2 . THR A 135 ? 0.57622 0.63433 0.43036 0.08819  0.08927  -0.06588 135 THR A CG2 
1902 N N   . PRO A 136 ? 0.61058 0.58788 0.49683 0.05923  0.03772  -0.08978 136 PRO A N   
1903 C CA  . PRO A 136 ? 0.71463 0.67309 0.62160 0.04901  0.02672  -0.08953 136 PRO A CA  
1904 C C   . PRO A 136 ? 0.79226 0.75326 0.72180 0.04856  0.03391  -0.08107 136 PRO A C   
1905 O O   . PRO A 136 ? 0.87093 0.83135 0.81785 0.03732  0.03064  -0.07075 136 PRO A O   
1906 C CB  . PRO A 136 ? 0.42302 0.35633 0.31830 0.05461  0.01337  -0.10940 136 PRO A CB  
1907 C CG  . PRO A 136 ? 0.38082 0.32106 0.24567 0.06233  0.01191  -0.12010 136 PRO A CG  
1908 C CD  . PRO A 136 ? 0.50886 0.47795 0.36649 0.06998  0.03116  -0.10860 136 PRO A CD  
1916 N N   . GLY A 137 ? 0.59551 0.56257 0.52510 0.06136  0.04348  -0.08506 137 GLY A N   
1917 C CA  . GLY A 137 ? 0.58839 0.55897 0.54030 0.06179  0.04751  -0.07767 137 GLY A CA  
1918 C C   . GLY A 137 ? 0.53387 0.52588 0.50050 0.05369  0.05580  -0.06195 137 GLY A C   
1919 O O   . GLY A 137 ? 0.56914 0.56683 0.55369 0.05346  0.05748  -0.05613 137 GLY A O   
1923 N N   . ASP A 138 ? 0.38979 0.39239 0.35013 0.04736  0.05922  -0.05530 138 ASP A N   
1924 C CA  . ASP A 138 ? 0.49906 0.51744 0.47400 0.04013  0.06559  -0.04247 138 ASP A CA  
1925 C C   . ASP A 138 ? 0.48631 0.49892 0.47134 0.02868  0.05827  -0.03759 138 ASP A C   
1926 O O   . ASP A 138 ? 0.47744 0.49907 0.47417 0.02320  0.06118  -0.03040 138 ASP A O   
1927 C CB  . ASP A 138 ? 0.31781 0.34862 0.28315 0.04003  0.07280  -0.03564 138 ASP A CB  
1928 C CG  . ASP A 138 ? 0.46604 0.51159 0.42123 0.05178  0.08381  -0.03702 138 ASP A CG  
1929 O OD1 . ASP A 138 ? 0.45954 0.51114 0.42368 0.05968  0.08855  -0.04109 138 ASP A OD1 
1930 O OD2 . ASP A 138 ? 0.50792 0.56173 0.44614 0.05420  0.08814  -0.03304 138 ASP A OD2 
1935 N N   . CYS A 139 ? 0.37110 0.37006 0.35272 0.02500  0.04883  -0.04142 139 CYS A N   
1936 C CA  . CYS A 139 ? 0.37403 0.37384 0.36371 0.01559  0.04434  -0.03583 139 CYS A CA  
1937 C C   . CYS A 139 ? 0.41904 0.42384 0.42142 0.01367  0.04474  -0.03162 139 CYS A C   
1938 O O   . CYS A 139 ? 0.33398 0.33534 0.34064 0.01814  0.04363  -0.03257 139 CYS A O   
1939 C CB  . CYS A 139 ? 0.49183 0.48074 0.47868 0.01068  0.03474  -0.03786 139 CYS A CB  
1940 S SG  . CYS A 139 ? 0.44886 0.43771 0.42331 0.00964  0.03035  -0.04117 139 CYS A SG  
1945 N N   . GLY A 140 ? 0.34483 0.35789 0.35246 0.00835  0.04530  -0.02780 140 GLY A N   
1946 C CA  . GLY A 140 ? 0.32939 0.35002 0.34515 0.00672  0.04454  -0.02545 140 GLY A CA  
1947 C C   . GLY A 140 ? 0.38095 0.41004 0.40518 0.00707  0.04832  -0.02581 140 GLY A C   
1948 O O   . GLY A 140 ? 0.29465 0.33062 0.32492 0.00461  0.04546  -0.02608 140 GLY A O   
1952 N N   . CYS A 141 ? 0.35248 0.38259 0.37749 0.00936  0.05395  -0.02507 141 CYS A N   
1953 C CA  . CYS A 141 ? 0.33315 0.37234 0.37133 0.00722  0.05749  -0.02196 141 CYS A CA  
1954 C C   . CYS A 141 ? 0.32922 0.36472 0.37108 0.00161  0.05533  -0.02215 141 CYS A C   
1955 O O   . CYS A 141 ? 0.38356 0.41210 0.41676 0.00207  0.05488  -0.02274 141 CYS A O   
1956 C CB  . CYS A 141 ? 0.30615 0.35127 0.34374 0.01146  0.06590  -0.01764 141 CYS A CB  
1957 S SG  . CYS A 141 ? 0.37791 0.43075 0.41636 0.02190  0.07001  -0.02017 141 CYS A SG  
1963 N N   . PRO A 142 ? 0.43384 0.47342 0.49048 -0.00319 0.05275  -0.02239 142 PRO A N   
1964 C CA  . PRO A 142 ? 0.52162 0.55305 0.58191 -0.00693 0.04802  -0.02689 142 PRO A CA  
1965 C C   . PRO A 142 ? 0.47643 0.50042 0.54518 -0.00965 0.05085  -0.02006 142 PRO A C   
1966 O O   . PRO A 142 ? 0.34473 0.37501 0.42151 -0.01158 0.05660  -0.00984 142 PRO A O   
1967 C CB  . PRO A 142 ? 0.38080 0.41831 0.45350 -0.01147 0.04082  -0.03203 142 PRO A CB  
1968 C CG  . PRO A 142 ? 0.45179 0.50229 0.53845 -0.01280 0.04476  -0.02374 142 PRO A CG  
1969 C CD  . PRO A 142 ? 0.34926 0.40154 0.42227 -0.00507 0.05237  -0.01986 142 PRO A CD  
1977 N N   . TYR A 143 ? 0.28067 0.29255 0.34808 -0.00875 0.04710  -0.02471 143 TYR A N   
1978 C CA  . TYR A 143 ? 0.40189 0.40148 0.48164 -0.01163 0.04619  -0.01864 143 TYR A CA  
1979 C C   . TYR A 143 ? 0.37889 0.36907 0.47477 -0.01716 0.03719  -0.02770 143 TYR A C   
1980 O O   . TYR A 143 ? 0.38673 0.37617 0.47556 -0.01412 0.03139  -0.04260 143 TYR A O   
1981 C CB  . TYR A 143 ? 0.44012 0.43049 0.51088 -0.00484 0.04616  -0.01874 143 TYR A CB  
1982 C CG  . TYR A 143 ? 0.51131 0.50931 0.56755 -0.00082 0.05184  -0.00988 143 TYR A CG  
1983 C CD1 . TYR A 143 ? 0.39797 0.40595 0.44022 0.00167  0.05343  -0.01433 143 TYR A CD1 
1984 C CD2 . TYR A 143 ? 0.52946 0.52343 0.58570 0.00035  0.05385  0.00300  143 TYR A CD2 
1985 C CE1 . TYR A 143 ? 0.35279 0.36492 0.38160 0.00489  0.05570  -0.00960 143 TYR A CE1 
1986 C CE2 . TYR A 143 ? 0.38686 0.38882 0.42651 0.00448  0.05683  0.00881  143 TYR A CE2 
1987 C CZ  . TYR A 143 ? 0.57480 0.58500 0.60080 0.00659  0.05715  0.00074  143 TYR A CZ  
1988 O OH  . TYR A 143 ? 0.45910 0.47452 0.46847 0.01024  0.05735  0.00334  143 TYR A OH  
1998 N N   . ILE A 144 ? 0.52237 0.50655 0.63975 -0.02572 0.03546  -0.01844 144 ILE A N   
1999 C CA  . ILE A 144 ? 0.52103 0.49427 0.65783 -0.03358 0.02402  -0.02749 144 ILE A CA  
2000 C C   . ILE A 144 ? 0.53558 0.49010 0.69505 -0.04093 0.02130  -0.01534 144 ILE A C   
2001 O O   . ILE A 144 ? 0.40817 0.36939 0.57336 -0.04399 0.03007  0.00559  144 ILE A O   
2002 C CB  . ILE A 144 ? 0.39938 0.39182 0.54826 -0.04137 0.02140  -0.02735 144 ILE A CB  
2003 C CG1 . ILE A 144 ? 0.23696 0.24537 0.36389 -0.03338 0.02323  -0.03621 144 ILE A CG1 
2004 C CG2 . ILE A 144 ? 0.52190 0.50300 0.69245 -0.05133 0.00623  -0.03791 144 ILE A CG2 
2005 C CD1 . ILE A 144 ? 0.52040 0.54807 0.65865 -0.03828 0.01870  -0.03668 144 ILE A CD1 
2017 N N   . TYR A 145 ? 0.52104 0.45149 0.69264 -0.04317 0.00863  -0.02845 145 TYR A N   
2018 C CA  . TYR A 145 ? 0.51249 0.41954 0.71189 -0.05250 0.00222  -0.01738 145 TYR A CA  
2019 C C   . TYR A 145 ? 0.56276 0.45414 0.78287 -0.06226 -0.01490 -0.03421 145 TYR A C   
2020 O O   . TYR A 145 ? 0.48037 0.37553 0.68640 -0.05743 -0.02212 -0.05778 145 TYR A O   
2021 C CB  . TYR A 145 ? 0.32052 0.20334 0.51439 -0.04184 0.00207  -0.01590 145 TYR A CB  
2022 C CG  . TYR A 145 ? 0.34191 0.20321 0.52736 -0.02992 -0.00786 -0.04334 145 TYR A CG  
2023 C CD1 . TYR A 145 ? 0.47253 0.34965 0.63016 -0.01684 -0.00363 -0.06084 145 TYR A CD1 
2024 C CD2 . TYR A 145 ? 0.49547 0.32084 0.70157 -0.03080 -0.02098 -0.05087 145 TYR A CD2 
2025 C CE1 . TYR A 145 ? 0.53744 0.40087 0.68617 -0.00390 -0.01013 -0.08534 145 TYR A CE1 
2026 C CE2 . TYR A 145 ? 0.63480 0.44150 0.83163 -0.01650 -0.02908 -0.07864 145 TYR A CE2 
2027 C CZ  . TYR A 145 ? 0.54444 0.37306 0.71156 -0.00244 -0.02250 -0.09578 145 TYR A CZ  
2028 O OH  . TYR A 145 ? 0.62830 0.44412 0.78517 0.01358  -0.02821 -0.12301 145 TYR A OH  
2038 N N   . LYS A 146 ? 0.41080 0.28586 0.66483 -0.07700 -0.02223 -0.02082 146 LYS A N   
2039 C CA  . LYS A 146 ? 0.53941 0.39549 0.81843 -0.08910 -0.04186 -0.03641 146 LYS A CA  
2040 C C   . LYS A 146 ? 0.57576 0.38653 0.86042 -0.08333 -0.05497 -0.05146 146 LYS A C   
2041 O O   . LYS A 146 ? 0.61655 0.40779 0.91164 -0.08204 -0.05135 -0.03332 146 LYS A O   
2042 C CB  . LYS A 146 ? 0.77619 0.64184 1.09643 -0.11158 -0.04448 -0.01249 146 LYS A CB  
2043 C CG  . LYS A 146 ? 0.67693 0.53299 1.01760 -0.12400 -0.06594 -0.03020 146 LYS A CG  
2044 C CD  . LYS A 146 ? 0.90874 0.78001 1.28261 -0.14279 -0.06718 -0.00455 146 LYS A CD  
2045 C CE  . LYS A 146 ? 0.91118 0.79413 1.29608 -0.15253 -0.08394 -0.02122 146 LYS A CE  
2046 N NZ  . LYS A 146 ? 0.77686 0.66081 1.19606 -0.17057 -0.09169 -0.00383 146 LYS A NZ  
2060 N N   . ARG A 147 ? 0.81597 0.61054 1.09322 -0.07864 -0.07076 -0.08476 147 ARG A N   
2061 C CA  . ARG A 147 ? 0.81198 0.57163 1.08297 -0.06761 -0.08208 -0.10240 147 ARG A CA  
2062 C C   . ARG A 147 ? 0.80470 0.55575 1.08627 -0.07858 -0.10104 -0.11720 147 ARG A C   
2063 O O   . ARG A 147 ? 0.75864 0.52066 1.02097 -0.07438 -0.10867 -0.14268 147 ARG A O   
2064 C CB  . ARG A 147 ? 0.89459 0.65361 1.13076 -0.04370 -0.07782 -0.12892 147 ARG A CB  
2065 C CG  . ARG A 147 ? 0.82288 0.55134 1.05135 -0.02852 -0.08594 -0.14631 147 ARG A CG  
2066 C CD  . ARG A 147 ? 0.79707 0.53665 0.99136 -0.00410 -0.07747 -0.16814 147 ARG A CD  
2067 N NE  . ARG A 147 ? 1.03701 0.80414 1.20614 -0.00207 -0.07789 -0.18799 147 ARG A NE  
2068 C CZ  . ARG A 147 ? 0.90965 0.69899 1.04718 0.01574  -0.06817 -0.20264 147 ARG A CZ  
2069 N NH1 . ARG A 147 ? 0.73332 0.52260 0.86208 0.03351  -0.05715 -0.20151 147 ARG A NH1 
2070 N NH2 . ARG A 147 ? 0.94601 0.76170 1.06122 0.01544  -0.06942 -0.21602 147 ARG A NH2 
2084 N N   . GLY A 148 ? 0.83883 0.57193 1.15044 -0.09275 -0.10878 -0.10009 148 GLY A N   
2085 C CA  . GLY A 148 ? 0.77399 0.49914 1.10158 -0.10604 -0.12723 -0.11090 148 GLY A CA  
2086 C C   . GLY A 148 ? 0.84925 0.61016 1.19244 -0.12379 -0.12726 -0.09922 148 GLY A C   
2087 O O   . GLY A 148 ? 0.95999 0.73932 1.32749 -0.13705 -0.11716 -0.06718 148 GLY A O   
2091 N N   . ASN A 149 ? 0.73067 0.50496 1.05910 -0.12293 -0.13806 -0.12410 149 ASN A N   
2092 C CA  . ASN A 149 ? 0.76564 0.57812 1.10621 -0.13638 -0.13869 -0.11563 149 ASN A CA  
2093 C C   . ASN A 149 ? 0.80769 0.65066 1.12145 -0.12524 -0.12822 -0.12330 149 ASN A C   
2094 O O   . ASN A 149 ? 0.62475 0.50315 0.94953 -0.13403 -0.12613 -0.11317 149 ASN A O   
2095 C CB  . ASN A 149 ? 0.75584 0.56521 1.10311 -0.14588 -0.16114 -0.13499 149 ASN A CB  
2096 C CG  . ASN A 149 ? 0.97397 0.76838 1.36175 -0.16528 -0.17086 -0.11814 149 ASN A CG  
2097 O OD1 . ASN A 149 ? 1.05042 0.83266 1.45795 -0.16975 -0.16152 -0.09320 149 ASN A OD1 
2098 N ND2 . ASN A 149 ? 0.93107 0.72755 1.33128 -0.17712 -0.19021 -0.13086 149 ASN A ND2 
2105 N N   . ASP A 150 ? 0.82064 0.65288 1.10151 -0.10568 -0.12128 -0.13980 150 ASP A N   
2106 C CA  . ASP A 150 ? 0.63295 0.49204 0.88599 -0.09415 -0.11247 -0.14970 150 ASP A CA  
2107 C C   . ASP A 150 ? 0.76698 0.63755 1.01580 -0.08790 -0.08908 -0.12629 150 ASP A C   
2108 O O   . ASP A 150 ? 0.70323 0.55029 0.95460 -0.08252 -0.08220 -0.11836 150 ASP A O   
2109 C CB  . ASP A 150 ? 0.61043 0.45897 0.82188 -0.07381 -0.11704 -0.18179 150 ASP A CB  
2110 C CG  . ASP A 150 ? 1.01267 0.85287 1.21706 -0.07602 -0.13733 -0.20381 150 ASP A CG  
2111 O OD1 . ASP A 150 ? 1.15799 0.96700 1.35815 -0.06952 -0.14467 -0.21783 150 ASP A OD1 
2112 O OD2 . ASP A 150 ? 1.18269 1.04806 1.38645 -0.08381 -0.14645 -0.20712 150 ASP A OD2 
2117 N N   . TYR A 151 ? 0.82695 0.73563 1.06400 -0.08605 -0.07619 -0.11282 151 TYR A N   
2118 C CA  . TYR A 151 ? 0.66204 0.58543 0.88015 -0.07513 -0.05362 -0.09438 151 TYR A CA  
2119 C C   . TYR A 151 ? 0.52142 0.44522 0.69896 -0.05574 -0.04853 -0.11232 151 TYR A C   
2120 O O   . TYR A 151 ? 0.65867 0.58856 0.81749 -0.05043 -0.05790 -0.13373 151 TYR A O   
2121 C CB  . TYR A 151 ? 0.59508 0.55570 0.81868 -0.07969 -0.04301 -0.07482 151 TYR A CB  
2122 C CG  . TYR A 151 ? 0.70733 0.67668 0.97062 -0.09621 -0.04048 -0.05027 151 TYR A CG  
2123 C CD1 . TYR A 151 ? 0.84508 0.79660 1.12409 -0.10098 -0.03400 -0.03241 151 TYR A CD1 
2124 C CD2 . TYR A 151 ? 0.82553 0.82443 1.11203 -0.10663 -0.04423 -0.04273 151 TYR A CD2 
2125 C CE1 . TYR A 151 ? 0.95538 0.91952 1.27061 -0.11654 -0.02988 -0.00646 151 TYR A CE1 
2126 C CE2 . TYR A 151 ? 0.96637 0.97979 1.29198 -0.12161 -0.03991 -0.01830 151 TYR A CE2 
2127 C CZ  . TYR A 151 ? 0.79742 0.79397 1.13656 -0.12698 -0.03204 0.00038  151 TYR A CZ  
2128 O OH  . TYR A 151 ? 0.82636 0.84184 1.20443 -0.14239 -0.02603 0.02810  151 TYR A OH  
2138 N N   . VAL A 152 ? 0.59349 0.51390 0.75793 -0.04542 -0.03380 -0.10217 152 VAL A N   
2139 C CA  . VAL A 152 ? 0.39427 0.31689 0.52684 -0.02802 -0.02758 -0.11540 152 VAL A CA  
2140 C C   . VAL A 152 ? 0.39724 0.34170 0.51548 -0.02295 -0.01046 -0.09693 152 VAL A C   
2141 O O   . VAL A 152 ? 0.43733 0.37913 0.56565 -0.02570 -0.00205 -0.07774 152 VAL A O   
2142 C CB  . VAL A 152 ? 0.47667 0.36909 0.61117 -0.01855 -0.03041 -0.12581 152 VAL A CB  
2143 C CG1 . VAL A 152 ? 0.49900 0.40169 0.60413 0.00011  -0.02192 -0.13752 152 VAL A CG1 
2144 C CG2 . VAL A 152 ? 0.61146 0.47601 0.76105 -0.02318 -0.04978 -0.14728 152 VAL A CG2 
2154 N N   . VAL A 153 ? 0.44951 0.41502 0.54381 -0.01581 -0.00640 -0.10243 153 VAL A N   
2155 C CA  . VAL A 153 ? 0.32332 0.30559 0.40366 -0.01082 0.00708  -0.08840 153 VAL A CA  
2156 C C   . VAL A 153 ? 0.37360 0.35109 0.44062 0.00112  0.01293  -0.09310 153 VAL A C   
2157 O O   . VAL A 153 ? 0.43136 0.40846 0.48652 0.00970  0.00952  -0.11028 153 VAL A O   
2158 C CB  . VAL A 153 ? 0.40329 0.40863 0.46876 -0.01006 0.00742  -0.08872 153 VAL A CB  
2159 C CG1 . VAL A 153 ? 0.33180 0.34882 0.39144 -0.00866 0.01867  -0.07216 153 VAL A CG1 
2160 C CG2 . VAL A 153 ? 0.49626 0.50802 0.57554 -0.01928 -0.00296 -0.09067 153 VAL A CG2 
2170 N N   . ILE A 154 ? 0.40420 0.38119 0.47284 0.00271  0.02155  -0.07838 154 ILE A N   
2171 C CA  . ILE A 154 ? 0.38764 0.36398 0.44868 0.01358  0.02630  -0.08032 154 ILE A CA  
2172 C C   . ILE A 154 ? 0.34770 0.34447 0.39509 0.01602  0.03455  -0.07148 154 ILE A C   
2173 O O   . ILE A 154 ? 0.43763 0.44261 0.47895 0.02457  0.03810  -0.07452 154 ILE A O   
2174 C CB  . ILE A 154 ? 0.58666 0.54392 0.66250 0.01464  0.02603  -0.07128 154 ILE A CB  
2175 C CG1 . ILE A 154 ? 0.37469 0.33714 0.45293 0.00795  0.03192  -0.05037 154 ILE A CG1 
2176 C CG2 . ILE A 154 ? 0.43390 0.36644 0.52774 0.01031  0.01600  -0.07868 154 ILE A CG2 
2177 C CD1 . ILE A 154 ? 0.36036 0.30987 0.44721 0.01101  0.03241  -0.03806 154 ILE A CD1 
2189 N N   . GLY A 155 ? 0.43183 0.43719 0.47669 0.00915  0.03714  -0.06100 155 GLY A N   
2190 C CA  . GLY A 155 ? 0.41468 0.43437 0.44866 0.01030  0.04216  -0.05417 155 GLY A CA  
2191 C C   . GLY A 155 ? 0.34698 0.36848 0.38097 0.00462  0.04398  -0.04415 155 GLY A C   
2192 O O   . GLY A 155 ? 0.37127 0.38986 0.41339 0.00023  0.04263  -0.04247 155 GLY A O   
2196 N N   . VAL A 156 ? 0.31182 0.33899 0.33848 0.00518  0.04660  -0.03818 156 VAL A N   
2197 C CA  . VAL A 156 ? 0.56255 0.58981 0.58659 0.00281  0.04784  -0.03219 156 VAL A CA  
2198 C C   . VAL A 156 ? 0.39084 0.41499 0.40977 0.00413  0.04919  -0.02734 156 VAL A C   
2199 O O   . VAL A 156 ? 0.35704 0.38356 0.37480 0.00560  0.04803  -0.02699 156 VAL A O   
2200 C CB  . VAL A 156 ? 0.35322 0.38723 0.37236 0.00175  0.04591  -0.03168 156 VAL A CB  
2201 C CG1 . VAL A 156 ? 0.39318 0.43332 0.41402 0.00116  0.04285  -0.03634 156 VAL A CG1 
2202 C CG2 . VAL A 156 ? 0.42395 0.46390 0.43841 0.00152  0.04569  -0.02932 156 VAL A CG2 
2212 N N   . HIS A 157 ? 0.37190 0.39350 0.38763 0.00457  0.05135  -0.02416 157 HIS A N   
2213 C CA  . HIS A 157 ? 0.46505 0.48440 0.47125 0.00673  0.05127  -0.02156 157 HIS A CA  
2214 C C   . HIS A 157 ? 0.39723 0.41558 0.39763 0.00552  0.04609  -0.02437 157 HIS A C   
2215 O O   . HIS A 157 ? 0.40281 0.41909 0.40382 0.00437  0.04455  -0.02625 157 HIS A O   
2216 C CB  . HIS A 157 ? 0.40797 0.42825 0.40916 0.00959  0.05623  -0.01912 157 HIS A CB  
2217 C CG  . HIS A 157 ? 0.50395 0.52357 0.48968 0.01334  0.05562  -0.01828 157 HIS A CG  
2218 N ND1 . HIS A 157 ? 0.29764 0.31900 0.27964 0.01420  0.05576  -0.01111 157 HIS A ND1 
2219 C CD2 . HIS A 157 ? 0.39426 0.41087 0.36613 0.01714  0.05324  -0.02460 157 HIS A CD2 
2220 C CE1 . HIS A 157 ? 0.49463 0.51727 0.45893 0.01813  0.05348  -0.01260 157 HIS A CE1 
2221 N NE2 . HIS A 157 ? 0.54318 0.56197 0.50064 0.01999  0.05168  -0.02247 157 HIS A NE2 
2229 N N   . THR A 158 ? 0.49720 0.51708 0.49468 0.00520  0.04208  -0.02319 158 THR A N   
2230 C CA  . THR A 158 ? 0.35366 0.37356 0.35083 0.00124  0.03524  -0.02444 158 THR A CA  
2231 C C   . THR A 158 ? 0.29775 0.31532 0.28587 0.00160  0.02840  -0.02607 158 THR A C   
2232 O O   . THR A 158 ? 0.37016 0.38350 0.35856 -0.00302 0.02039  -0.02888 158 THR A O   
2233 C CB  . THR A 158 ? 0.40584 0.43785 0.41482 -0.00186 0.03483  -0.02103 158 THR A CB  
2234 O OG1 . THR A 158 ? 0.61431 0.64851 0.62805 -0.00854 0.02862  -0.01868 158 THR A OG1 
2235 C CG2 . THR A 158 ? 0.45383 0.49384 0.46720 0.00185  0.03474  -0.01886 158 THR A CG2 
2243 N N   . ALA A 159 ? 0.26843 0.28825 0.24867 0.00623  0.02965  -0.02374 159 ALA A N   
2244 C CA  . ALA A 159 ? 0.46031 0.48080 0.42869 0.00714  0.02121  -0.02548 159 ALA A CA  
2245 C C   . ALA A 159 ? 0.33669 0.36058 0.29294 0.01363  0.02530  -0.01957 159 ALA A C   
2246 O O   . ALA A 159 ? 0.41448 0.43936 0.37752 0.01552  0.03359  -0.01247 159 ALA A O   
2247 C CB  . ALA A 159 ? 0.43793 0.46845 0.41912 0.00236  0.01248  -0.02256 159 ALA A CB  
2253 N N   . ALA A 160 ? 0.51870 0.54427 0.45679 0.01641  0.01821  -0.02197 160 ALA A N   
2254 C CA  . ALA A 160 ? 0.52433 0.55645 0.44705 0.02272  0.02119  -0.01327 160 ALA A CA  
2255 C C   . ALA A 160 ? 0.36053 0.39790 0.26582 0.02431  0.00776  -0.01676 160 ALA A C   
2256 O O   . ALA A 160 ? 0.68620 0.71756 0.57972 0.02322  -0.00053 -0.03080 160 ALA A O   
2257 C CB  . ALA A 160 ? 0.49993 0.53190 0.40854 0.02794  0.03276  -0.01360 160 ALA A CB  
2263 N N   . ALA A 161 ? 0.53031 0.57748 0.43485 0.02708  0.00381  -0.00446 161 ALA A N   
2264 C CA  . ALA A 161 ? 0.56767 0.62328 0.45742 0.02832  -0.01166 -0.00665 161 ALA A CA  
2265 C C   . ALA A 161 ? 0.76047 0.81736 0.61325 0.03499  -0.01214 -0.01358 161 ALA A C   
2266 O O   . ALA A 161 ? 0.80125 0.85975 0.64115 0.04067  0.00193  -0.00788 161 ALA A O   
2267 C CB  . ALA A 161 ? 0.53912 0.60624 0.43818 0.03173  -0.01594 0.01059  161 ALA A CB  
2273 N N   . ARG A 162 ? 0.84590 0.90400 0.68213 0.03441  -0.02878 -0.02662 162 ARG A N   
2274 C CA  . ARG A 162 ? 0.91245 0.97226 0.70876 0.04292  -0.03112 -0.03794 162 ARG A CA  
2275 C C   . ARG A 162 ? 0.85546 0.93407 0.62692 0.05094  -0.03196 -0.02215 162 ARG A C   
2276 O O   . ARG A 162 ? 0.85162 0.93725 0.58476 0.06001  -0.03228 -0.02945 162 ARG A O   
2277 C CB  . ARG A 162 ? 0.80458 0.85446 0.59181 0.03888  -0.05151 -0.06137 162 ARG A CB  
2278 C CG  . ARG A 162 ? 0.83873 0.87972 0.58913 0.04868  -0.05162 -0.08348 162 ARG A CG  
2279 C CD  . ARG A 162 ? 1.15770 1.19026 0.91079 0.05464  -0.03050 -0.08601 162 ARG A CD  
2280 N NE  . ARG A 162 ? 1.32366 1.33275 1.09752 0.04847  -0.03470 -0.10121 162 ARG A NE  
2281 C CZ  . ARG A 162 ? 1.09254 1.09334 0.87859 0.05139  -0.01967 -0.10192 162 ARG A CZ  
2282 N NH1 . ARG A 162 ? 1.15842 1.17360 0.94430 0.05775  0.00068  -0.08769 162 ARG A NH1 
2283 N NH2 . ARG A 162 ? 1.02166 0.99965 0.82245 0.04724  -0.02643 -0.11582 162 ARG A NH2 
2297 N N   . GLY A 163 ? 0.78516 0.87233 0.57650 0.04922  -0.03228 -0.00054 163 GLY A N   
2298 C CA  . GLY A 163 ? 0.71621 0.81946 0.48772 0.05683  -0.03171 0.02013  163 GLY A CA  
2299 C C   . GLY A 163 ? 0.98467 1.08925 0.75546 0.06040  -0.00963 0.03807  163 GLY A C   
2300 O O   . GLY A 163 ? 1.11887 1.22296 0.87444 0.06352  0.00343  0.02960  163 GLY A O   
2304 N N   . GLY A 164 ? 0.99015 1.09639 0.78080 0.05999  -0.00595 0.06313  164 GLY A N   
2305 C CA  . GLY A 164 ? 0.90754 1.01395 0.70389 0.06044  0.01259  0.08335  164 GLY A CA  
2306 C C   . GLY A 164 ? 0.95741 1.04810 0.78576 0.05339  0.02467  0.07690  164 GLY A C   
2307 O O   . GLY A 164 ? 0.78939 0.87251 0.62153 0.05054  0.02436  0.05446  164 GLY A O   
2311 N N   . ASN A 165 ? 1.03990 1.12458 0.89187 0.05025  0.03374  0.09714  165 ASN A N   
2312 C CA  . ASN A 165 ? 0.81432 0.88616 0.69474 0.04341  0.04447  0.09266  165 ASN A CA  
2313 C C   . ASN A 165 ? 0.78106 0.83722 0.69139 0.04023  0.03573  0.08406  165 ASN A C   
2314 O O   . ASN A 165 ? 0.77269 0.82071 0.70252 0.04098  0.03200  0.09791  165 ASN A O   
2315 C CB  . ASN A 165 ? 0.52913 0.60198 0.42195 0.04006  0.05676  0.11773  165 ASN A CB  
2316 C CG  . ASN A 165 ? 1.01041 1.10572 0.87612 0.04345  0.06997  0.12677  165 ASN A CG  
2317 O OD1 . ASN A 165 ? 1.19198 1.30134 1.02322 0.05121  0.06785  0.11642  165 ASN A OD1 
2318 N ND2 . ASN A 165 ? 1.20578 1.30580 1.08858 0.03769  0.08349  0.14593  165 ASN A ND2 
2325 N N   . THR A 166 ? 0.67936 0.73191 0.59341 0.03775  0.03263  0.06179  166 THR A N   
2326 C CA  . THR A 166 ? 0.63234 0.67557 0.57326 0.03515  0.02764  0.05319  166 THR A CA  
2327 C C   . THR A 166 ? 0.33688 0.37586 0.28185 0.03019  0.03198  0.03489  166 THR A C   
2328 O O   . THR A 166 ? 0.45300 0.49550 0.38400 0.02955  0.02729  0.02213  166 THR A O   
2329 C CB  . THR A 166 ? 0.72510 0.77609 0.66713 0.03828  0.01355  0.05102  166 THR A CB  
2330 O OG1 . THR A 166 ? 0.79147 0.84524 0.73496 0.04423  0.00868  0.07025  166 THR A OG1 
2331 C CG2 . THR A 166 ? 0.37248 0.42091 0.34090 0.03626  0.01123  0.04056  166 THR A CG2 
2339 N N   . VAL A 167 ? 0.48951 0.51966 0.45370 0.02669  0.03923  0.03384  167 VAL A N   
2340 C CA  . VAL A 167 ? 0.50122 0.52807 0.47185 0.02253  0.04212  0.01924  167 VAL A CA  
2341 C C   . VAL A 167 ? 0.41421 0.43802 0.40440 0.02175  0.03828  0.01347  167 VAL A C   
2342 O O   . VAL A 167 ? 0.35305 0.37372 0.35601 0.02521  0.03618  0.01962  167 VAL A O   
2343 C CB  . VAL A 167 ? 0.45278 0.47694 0.42924 0.01953  0.05223  0.02118  167 VAL A CB  
2344 C CG1 . VAL A 167 ? 0.42705 0.46038 0.38356 0.02227  0.05835  0.02283  167 VAL A CG1 
2345 C CG2 . VAL A 167 ? 0.44199 0.45925 0.43571 0.01779  0.05475  0.03433  167 VAL A CG2 
2355 N N   . ILE A 168 ? 0.37569 0.40116 0.36823 0.01836  0.03773  0.00209  168 ILE A N   
2356 C CA  . ILE A 168 ? 0.30452 0.33310 0.31249 0.01816  0.03645  -0.00325 168 ILE A CA  
2357 C C   . ILE A 168 ? 0.42944 0.45350 0.44240 0.01507  0.04197  -0.00977 168 ILE A C   
2358 O O   . ILE A 168 ? 0.47264 0.49578 0.47860 0.01156  0.04350  -0.01329 168 ILE A O   
2359 C CB  . ILE A 168 ? 0.46351 0.50309 0.47195 0.01554  0.02989  -0.00688 168 ILE A CB  
2360 C CG1 . ILE A 168 ? 0.48725 0.53361 0.49094 0.01807  0.02144  -0.00120 168 ILE A CG1 
2361 C CG2 . ILE A 168 ? 0.30972 0.35921 0.33440 0.01632  0.03162  -0.00974 168 ILE A CG2 
2362 C CD1 . ILE A 168 ? 0.38754 0.43626 0.40180 0.02569  0.02060  0.00721  168 ILE A CD1 
2374 N N   . CYS A 169 ? 0.33234 0.35314 0.35721 0.01756  0.04362  -0.01233 169 CYS A N   
2375 C CA  . CYS A 169 ? 0.42945 0.44788 0.45828 0.01529  0.04633  -0.01998 169 CYS A CA  
2376 C C   . CYS A 169 ? 0.55294 0.58281 0.58500 0.01798  0.04621  -0.02672 169 CYS A C   
2377 O O   . CYS A 169 ? 0.38314 0.41587 0.42295 0.02485  0.04586  -0.02908 169 CYS A O   
2378 C CB  . CYS A 169 ? 0.35903 0.36451 0.39774 0.01583  0.04659  -0.01986 169 CYS A CB  
2379 S SG  . CYS A 169 ? 0.45862 0.46114 0.50300 0.01416  0.04561  -0.03280 169 CYS A SG  
2385 N N   . ALA A 170 ? 0.49711 0.53512 0.52407 0.01360  0.04697  -0.02843 170 ALA A N   
2386 C CA  . ALA A 170 ? 0.32702 0.38111 0.35606 0.01510  0.04864  -0.03102 170 ALA A CA  
2387 C C   . ALA A 170 ? 0.32218 0.37644 0.35014 0.01939  0.05067  -0.04065 170 ALA A C   
2388 O O   . ALA A 170 ? 0.32358 0.36905 0.34812 0.01618  0.04925  -0.04384 170 ALA A O   
2389 C CB  . ALA A 170 ? 0.52541 0.58627 0.55044 0.00775  0.04767  -0.02587 170 ALA A CB  
2395 N N   . THR A 171 ? 0.39547 0.46166 0.42664 0.02751  0.05336  -0.04638 171 THR A N   
2396 C CA  . THR A 171 ? 0.60344 0.66659 0.63171 0.03467  0.05362  -0.06015 171 THR A CA  
2397 C C   . THR A 171 ? 0.33398 0.42210 0.35341 0.03891  0.05871  -0.06416 171 THR A C   
2398 O O   . THR A 171 ? 0.44210 0.54893 0.46038 0.03382  0.06208  -0.05296 171 THR A O   
2399 C CB  . THR A 171 ? 0.28402 0.33576 0.32272 0.04498  0.05228  -0.06686 171 THR A CB  
2400 O OG1 . THR A 171 ? 0.43778 0.50915 0.48366 0.05268  0.05639  -0.06314 171 THR A OG1 
2401 C CG2 . THR A 171 ? 0.33450 0.36374 0.38076 0.04007  0.04775  -0.05884 171 THR A CG2 
2409 N N   . GLN A 172 ? 1.03198 1.12022 1.04509 0.04835  0.05876  -0.08011 172 GLN A N   
2410 C CA  . GLN A 172 ? 0.77588 0.89055 0.77533 0.05503  0.06442  -0.08597 172 GLN A CA  
2411 C C   . GLN A 172 ? 0.72646 0.84841 0.71308 0.04487  0.06262  -0.07795 172 GLN A C   
2412 O O   . GLN A 172 ? 0.98480 1.09241 0.96502 0.04151  0.05532  -0.08531 172 GLN A O   
2413 C CB  . GLN A 172 ? 0.51712 0.66187 0.52370 0.06059  0.07389  -0.07714 172 GLN A CB  
2414 C CG  . GLN A 172 ? 0.52675 0.70622 0.51911 0.06779  0.08275  -0.07925 172 GLN A CG  
2415 C CD  . GLN A 172 ? 0.71684 0.90611 0.71074 0.08475  0.08779  -0.09151 172 GLN A CD  
2416 O OE1 . GLN A 172 ? 1.09209 1.25749 1.09006 0.09447  0.08289  -0.10806 172 GLN A OE1 
2417 N NE2 . GLN A 172 ? 0.87091 1.09156 0.86362 0.08701  0.09630  -0.08124 172 GLN A NE2 
2426 I I   . IOD B .   ? 0.63459 0.91310 0.85787 -0.08150 0.01376  0.08455  201 IOD A I   
2427 I I   . IOD C .   ? 1.06339 1.19652 1.20579 0.08248  -0.06872 0.09397  202 IOD A I   
2428 I I   . IOD D .   ? 0.60123 0.69409 0.79521 0.08042  0.03978  -0.02297 203 IOD A I   
2429 I I   . IOD E .   ? 0.94906 1.07385 1.10941 0.08005  0.03786  -0.00421 204 IOD A I   
2430 I I   . IOD F .   ? 1.65662 1.52065 1.78784 0.02187  -0.08031 0.19609  205 IOD A I   
2431 I I   . IOD G .   ? 1.30718 1.50409 1.25939 0.03987  0.07572  -0.04889 206 IOD A I   
2432 I I   . IOD H .   ? 1.21036 1.46207 1.11205 -0.01148 -0.04069 0.35209  207 IOD A I   
2433 I I   . IOD I .   ? 1.44748 1.68013 1.31389 0.01447  -0.11313 -0.12423 208 IOD A I   
2434 C C01 . AG7 J .   ? 0.54377 0.54788 0.48825 -0.00295 -0.02036 -0.05083 209 AG7 A C01 
2435 C C02 . AG7 J .   ? 0.58920 0.58806 0.55713 -0.01409 -0.02515 -0.04921 209 AG7 A C02 
2436 O O03 . AG7 J .   ? 0.32034 0.32496 0.25781 0.00446  -0.00681 -0.04775 209 AG7 A O03 
2437 C C04 . AG7 J .   ? 0.42847 0.42208 0.40434 -0.01295 -0.01260 -0.04516 209 AG7 A C04 
2438 C C05 . AG7 J .   ? 0.41679 0.40736 0.41447 -0.02450 -0.01780 -0.03963 209 AG7 A C05 
2439 C C06 . AG7 J .   ? 0.45434 0.46871 0.47325 -0.03132 -0.01527 -0.02652 209 AG7 A C06 
2440 C C07 . AG7 J .   ? 0.30050 0.32981 0.32206 -0.02536 -0.00180 -0.02018 209 AG7 A C07 
2441 C C08 . AG7 J .   ? 0.35885 0.41159 0.39810 -0.02810 0.00184  -0.01082 209 AG7 A C08 
2442 C C09 . AG7 J .   ? 0.36507 0.43071 0.42286 -0.03845 -0.00712 -0.00452 209 AG7 A C09 
2443 C C10 . AG7 J .   ? 0.39941 0.45071 0.45871 -0.04768 -0.02207 -0.00851 209 AG7 A C10 
2444 C C11 . AG7 J .   ? 0.47235 0.49556 0.51029 -0.04329 -0.02659 -0.02119 209 AG7 A C11 
2445 N N12 . AG7 J .   ? 0.60554 0.58885 0.55996 0.00346  0.00568  -0.05145 209 AG7 A N12 
2446 C C13 . AG7 J .   ? 0.46464 0.44070 0.40781 0.01309  0.01317  -0.05806 209 AG7 A C13 
2447 C C14 . AG7 J .   ? 0.42289 0.41195 0.35304 0.02116  0.02385  -0.05449 209 AG7 A C14 
2448 C C15 . AG7 J .   ? 0.53385 0.52716 0.44129 0.02571  0.01874  -0.05863 209 AG7 A C15 
2449 C C16 . AG7 J .   ? 0.57175 0.57981 0.46733 0.03344  0.03156  -0.05032 209 AG7 A C16 
2450 N N17 . AG7 J .   ? 0.62708 0.63675 0.49551 0.04235  0.02978  -0.05958 209 AG7 A N17 
2451 O O18 . AG7 J .   ? 0.34301 0.35961 0.25188 0.03145  0.04096  -0.03758 209 AG7 A O18 
2452 C C19 . AG7 J .   ? 0.49228 0.46679 0.45204 0.01136  0.01927  -0.05255 209 AG7 A C19 
2453 C C20 . AG7 J .   ? 0.51999 0.48166 0.49254 0.00335  0.00943  -0.05204 209 AG7 A C20 
2454 C C21 . AG7 J .   ? 0.68307 0.62214 0.64775 0.00687  -0.00065 -0.06513 209 AG7 A C21 
2455 O O22 . AG7 J .   ? 0.67897 0.60565 0.65729 -0.00363 -0.01237 -0.06239 209 AG7 A O22 
2456 O O23 . AG7 J .   ? 0.68810 0.62114 0.63667 0.01826  0.00157  -0.07688 209 AG7 A O23 
2457 C C47 . AG7 J .   ? 0.53120 0.50791 0.48966 -0.00405 -0.00837 -0.05552 209 AG7 A C47 
2458 O O48 . AG7 J .   ? 0.63186 0.59066 0.58305 -0.00364 -0.01784 -0.06712 209 AG7 A O48 
2459 C C50 . AG7 J .   ? 0.81416 0.72484 0.78738 -0.00765 -0.02800 -0.07372 209 AG7 A C50 
2460 C C53 . AG7 J .   ? 0.85363 0.77704 0.84425 -0.02345 -0.03563 -0.06222 209 AG7 A C53 
2461 C C57 . AG7 J .   ? 0.49026 0.50205 0.42102 -0.00205 -0.03409 -0.05408 209 AG7 A C57 
2462 N N58 . AG7 J .   ? 0.50877 0.53807 0.44573 0.00206  -0.02616 -0.03962 209 AG7 A N58 
2463 C C59 . AG7 J .   ? 0.39720 0.44300 0.35389 -0.00171 -0.03190 -0.03041 209 AG7 A C59 
2464 O O60 . AG7 J .   ? 0.52769 0.58016 0.50071 -0.01056 -0.04404 -0.03145 209 AG7 A O60 
2465 C C78 . AG7 J .   ? 0.47230 0.47312 0.37037 0.00629  -0.03869 -0.06896 209 AG7 A C78 
2466 C C81 . AG7 J .   ? 0.48135 0.49664 0.35836 0.01181  -0.04578 -0.06679 209 AG7 A C81 
2467 F F1  . AG7 J .   ? 0.37701 0.47099 0.45346 -0.03928 -0.00150 0.00509  209 AG7 A F1  
2468 C C82 . AG7 J .   ? 0.61826 0.61255 0.50326 0.01654  -0.02168 -0.07129 209 AG7 A C82 
2469 C C83 . AG7 J .   ? 0.82707 0.82037 0.68586 0.04220  0.01470  -0.07752 209 AG7 A C83 
2470 C C84 . AG7 J .   ? 0.48911 0.46900 0.37647 0.03216  0.01037  -0.07660 209 AG7 A C84 
2471 C C1  . AG7 J .   ? 0.48709 0.54370 0.44877 0.00598  -0.02243 -0.01740 209 AG7 A C1  
2472 C C2  . AG7 J .   ? 0.41318 0.48723 0.39175 0.00809  -0.02707 -0.00721 209 AG7 A C2  
2473 C C3  . AG7 J .   ? 0.65094 0.72246 0.62956 0.01620  -0.01567 0.00157  209 AG7 A C3  
2474 O O4  . AG7 J .   ? 0.57814 0.63518 0.54306 0.01690  -0.00508 -0.00214 209 AG7 A O4  
2475 N N5  . AG7 J .   ? 0.54214 0.59138 0.49672 0.01171  -0.00867 -0.01395 209 AG7 A N5  
2476 C C4  . AG7 J .   ? 0.59243 0.67229 0.58561 0.02413  -0.01406 0.01379  209 AG7 A C4  
2518 O O   . HOH K .   ? 0.48512 0.53882 0.48151 0.07351  0.08844  -0.04908 301 HOH A O   
2519 O O   . HOH K .   ? 0.35007 0.51561 0.44658 0.01561  -0.03094 0.02050  302 HOH A O   
2520 O O   . HOH K .   ? 0.49913 0.46209 0.65793 0.13264  0.02033  -0.03690 303 HOH A O   
2521 O O   . HOH K .   ? 0.45220 0.61402 0.49464 0.04408  0.07398  -0.04034 304 HOH A O   
2522 O O   . HOH K .   ? 0.49564 0.45286 0.56017 -0.04798 -0.00999 0.04193  305 HOH A O   
2523 O O   . HOH K .   ? 0.91616 0.89380 0.68920 0.07552  0.00045  -0.13274 306 HOH A O   
2524 O O   . HOH K .   ? 0.49871 0.62055 0.57108 -0.01948 0.13118  0.16199  307 HOH A O   
2525 O O   . HOH K .   ? 0.50332 0.44415 0.58419 0.04293  0.02236  0.10322  308 HOH A O   
2526 O O   . HOH K .   ? 0.34311 0.47251 0.39313 0.01010  0.05583  -0.01302 309 HOH A O   
2527 O O   . HOH K .   ? 0.55318 0.60132 0.66841 0.07013  0.00062  0.01805  310 HOH A O   
2528 O O   . HOH K .   ? 0.53366 0.59599 0.41211 0.04158  0.06416  0.01730  311 HOH A O   
2529 O O   . HOH K .   ? 0.70897 0.72765 0.48969 0.07959  0.03346  -0.09775 312 HOH A O   
2530 O O   . HOH K .   ? 0.50526 0.58455 0.58020 0.08014  0.05711  -0.06628 313 HOH A O   
2531 O O   . HOH K .   ? 0.49037 0.81404 0.69338 0.03321  0.17053  0.07892  314 HOH A O   
2532 O O   . HOH K .   ? 0.43077 0.40156 0.69695 -0.09086 0.01967  0.04584  315 HOH A O   
2533 O O   . HOH K .   ? 0.42296 0.53363 0.58425 0.09584  0.04915  -0.02838 316 HOH A O   
2534 O O   . HOH K .   ? 0.47609 0.51684 0.76348 -0.09894 0.04991  0.09295  317 HOH A O   
2535 O O   . HOH K .   ? 0.65648 0.45262 0.88112 -0.09751 -0.11005 0.32386  318 HOH A O   
2536 O O   . HOH K .   ? 0.40656 0.35211 0.48986 0.05586  -0.01016 0.02270  319 HOH A O   
2537 O O   . HOH K .   ? 0.47921 0.40570 0.56971 0.08086  -0.00399 -0.00488 320 HOH A O   
2538 O O   . HOH K .   ? 0.46109 0.49084 0.72005 -0.08632 0.03095  0.04146  321 HOH A O   
2539 O O   . HOH K .   ? 0.53352 0.63896 0.81021 -0.08365 0.05667  0.06760  322 HOH A O   
2540 O O   . HOH K .   ? 0.60103 0.84048 0.49221 -0.00068 -0.16762 -0.16507 323 HOH A O   
# 
