data_9DA0
# 
_entry.id   9DA0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9DA0         pdb_00009da0 10.2210/pdb9da0/pdb 
WWPDB D_1000287673 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-19 ? 
2 'Structure model' 1 1 2025-03-12 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_citation.journal_volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9DA0 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              vprasad@bcm.edu 
_pdbx_contact_author.name_first         B.V.V 
_pdbx_contact_author.name_last          Prasad 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1172-2071 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhao, B.'       1 ?                   
'Pham, S.H.'     2 0000-0001-6642-8796 
'Neetu, N.'      3 ?                   
'Sankaran, B.'   4 0000-0002-3266-8131 
'Prasad, B.V.V.' 5 0000-0002-1172-2071 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Virol. 
_citation.journal_id_ASTM           JOVIAM 
_citation.journal_id_CSD            0825 
_citation.journal_id_ISSN           1098-5514 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            99 
_citation.language                  ? 
_citation.page_first                e0175724 
_citation.page_last                 e0175724 
_citation.title                     
'Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1128/jvi.01757-24 
_citation.pdbx_database_id_PubMed   39873493 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Pham, S.'       1  ?                   
primary 'Zhao, B.'       2  ?                   
primary 'Neetu, N.'      3  ?                   
primary 'Sankaran, B.'   4  ?                   
primary 'Patil, K.'      5  ?                   
primary 'Ramani, S.'     6  0000-0001-5631-8534 
primary 'Song, Y.'       7  ?                   
primary 'Estes, M.K.'    8  0000-0002-4813-4249 
primary 'Palzkill, T.'   9  ?                   
primary 'Prasad, B.V.V.' 10 0000-0002-1172-2071 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Peptidase C37' 19218.146 1  ? R112A ? ? 
2 non-polymer syn 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
600.678   1  ? ?     ? ? 
3 water       nat water 18.015    38 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGATVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEATLE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGATVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEATLE
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
AG7 
3 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   PRO n 
1 3   PRO n 
1 4   SER n 
1 5   ILE n 
1 6   TRP n 
1 7   SER n 
1 8   ARG n 
1 9   ILE n 
1 10  VAL n 
1 11  ASN n 
1 12  PHE n 
1 13  GLY n 
1 14  SER n 
1 15  GLY n 
1 16  TRP n 
1 17  GLY n 
1 18  PHE n 
1 19  TRP n 
1 20  VAL n 
1 21  SER n 
1 22  PRO n 
1 23  SER n 
1 24  LEU n 
1 25  PHE n 
1 26  ILE n 
1 27  THR n 
1 28  SER n 
1 29  THR n 
1 30  HIS n 
1 31  VAL n 
1 32  ILE n 
1 33  PRO n 
1 34  GLN n 
1 35  GLY n 
1 36  ALA n 
1 37  LYS n 
1 38  GLU n 
1 39  PHE n 
1 40  PHE n 
1 41  GLY n 
1 42  VAL n 
1 43  PRO n 
1 44  ILE n 
1 45  LYS n 
1 46  GLN n 
1 47  ILE n 
1 48  GLN n 
1 49  VAL n 
1 50  HIS n 
1 51  LYS n 
1 52  SER n 
1 53  GLY n 
1 54  GLU n 
1 55  PHE n 
1 56  CYS n 
1 57  ARG n 
1 58  LEU n 
1 59  ARG n 
1 60  PHE n 
1 61  PRO n 
1 62  LYS n 
1 63  PRO n 
1 64  ILE n 
1 65  ARG n 
1 66  THR n 
1 67  ASP n 
1 68  VAL n 
1 69  THR n 
1 70  GLY n 
1 71  MET n 
1 72  ILE n 
1 73  LEU n 
1 74  GLU n 
1 75  GLU n 
1 76  GLY n 
1 77  ALA n 
1 78  PRO n 
1 79  GLU n 
1 80  GLY n 
1 81  THR n 
1 82  VAL n 
1 83  VAL n 
1 84  THR n 
1 85  LEU n 
1 86  LEU n 
1 87  ILE n 
1 88  LYS n 
1 89  ARG n 
1 90  SER n 
1 91  THR n 
1 92  GLY n 
1 93  GLU n 
1 94  LEU n 
1 95  MET n 
1 96  PRO n 
1 97  LEU n 
1 98  ALA n 
1 99  ALA n 
1 100 ARG n 
1 101 MET n 
1 102 GLY n 
1 103 THR n 
1 104 HIS n 
1 105 ALA n 
1 106 THR n 
1 107 MET n 
1 108 LYS n 
1 109 ILE n 
1 110 GLN n 
1 111 GLY n 
1 112 ALA n 
1 113 THR n 
1 114 VAL n 
1 115 GLY n 
1 116 GLY n 
1 117 GLN n 
1 118 MET n 
1 119 GLY n 
1 120 MET n 
1 121 LEU n 
1 122 LEU n 
1 123 THR n 
1 124 GLY n 
1 125 SER n 
1 126 ASN n 
1 127 ALA n 
1 128 LYS n 
1 129 SER n 
1 130 MET n 
1 131 ASP n 
1 132 LEU n 
1 133 GLY n 
1 134 THR n 
1 135 THR n 
1 136 PRO n 
1 137 GLY n 
1 138 ASP n 
1 139 CYS n 
1 140 GLY n 
1 141 CYS n 
1 142 PRO n 
1 143 TYR n 
1 144 ILE n 
1 145 TYR n 
1 146 LYS n 
1 147 ARG n 
1 148 GLY n 
1 149 ASN n 
1 150 ASP n 
1 151 TYR n 
1 152 VAL n 
1 153 VAL n 
1 154 ILE n 
1 155 GLY n 
1 156 VAL n 
1 157 HIS n 
1 158 THR n 
1 159 ALA n 
1 160 ALA n 
1 161 ALA n 
1 162 ARG n 
1 163 GLY n 
1 164 GLY n 
1 165 ASN n 
1 166 THR n 
1 167 VAL n 
1 168 ILE n 
1 169 CYS n 
1 170 ALA n 
1 171 THR n 
1 172 GLN n 
1 173 GLY n 
1 174 SER n 
1 175 GLU n 
1 176 GLY n 
1 177 GLU n 
1 178 ALA n 
1 179 THR n 
1 180 LEU n 
1 181 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   181 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ORF1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      Norovirus 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     142786 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli B' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     37762 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
AG7 non-polymer         . 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
'RUPINTRIVIR, bound form' 'C31 H41 F N4 O7' 600.678 
ALA 'L-peptide linking' y ALANINE ?                         'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE ?                         'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                         'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                         'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE ?                         'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                         'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                         'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE ?                         'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE ?                         'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER ?                         'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                         'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE ?                         'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE ?                         'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE ?                         'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                         'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE ?                         'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE ?                         'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE ?                         'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                         'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE ?                         'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE ?                         'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA A . n 
A 1 2   PRO 2   2   2   PRO PRO A . n 
A 1 3   PRO 3   3   3   PRO PRO A . n 
A 1 4   SER 4   4   4   SER SER A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   TRP 6   6   6   TRP TRP A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   ARG 8   8   8   ARG ARG A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  VAL 10  10  10  VAL VAL A . n 
A 1 11  ASN 11  11  11  ASN ASN A . n 
A 1 12  PHE 12  12  12  PHE PHE A . n 
A 1 13  GLY 13  13  13  GLY GLY A . n 
A 1 14  SER 14  14  14  SER SER A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  TRP 16  16  16  TRP TRP A . n 
A 1 17  GLY 17  17  17  GLY GLY A . n 
A 1 18  PHE 18  18  18  PHE PHE A . n 
A 1 19  TRP 19  19  19  TRP TRP A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  PRO 22  22  22  PRO PRO A . n 
A 1 23  SER 23  23  23  SER SER A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  ILE 26  26  26  ILE ILE A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  SER 28  28  28  SER SER A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  HIS 30  30  30  HIS HIS A . n 
A 1 31  VAL 31  31  31  VAL VAL A . n 
A 1 32  ILE 32  32  32  ILE ILE A . n 
A 1 33  PRO 33  33  33  PRO PRO A . n 
A 1 34  GLN 34  34  34  GLN GLN A . n 
A 1 35  GLY 35  35  35  GLY GLY A . n 
A 1 36  ALA 36  36  36  ALA ALA A . n 
A 1 37  LYS 37  37  37  LYS LYS A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  PHE 39  39  39  PHE PHE A . n 
A 1 40  PHE 40  40  40  PHE PHE A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  PRO 43  43  43  PRO PRO A . n 
A 1 44  ILE 44  44  44  ILE ILE A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  ILE 47  47  47  ILE ILE A . n 
A 1 48  GLN 48  48  48  GLN GLN A . n 
A 1 49  VAL 49  49  49  VAL VAL A . n 
A 1 50  HIS 50  50  50  HIS HIS A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  PHE 55  55  55  PHE PHE A . n 
A 1 56  CYS 56  56  56  CYS CYS A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  PHE 60  60  60  PHE PHE A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  ILE 64  64  64  ILE ILE A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  THR 69  69  69  THR THR A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  MET 71  71  71  MET MET A . n 
A 1 72  ILE 72  72  72  ILE ILE A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLU 74  74  74  GLU GLU A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  GLY 76  76  76  GLY GLY A . n 
A 1 77  ALA 77  77  77  ALA ALA A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  GLU 79  79  79  GLU GLU A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  THR 81  81  81  THR THR A . n 
A 1 82  VAL 82  82  82  VAL VAL A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  LEU 85  85  85  LEU LEU A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  ILE 87  87  87  ILE ILE A . n 
A 1 88  LYS 88  88  88  LYS LYS A . n 
A 1 89  ARG 89  89  89  ARG ARG A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  GLU 93  93  93  GLU GLU A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  MET 95  95  95  MET MET A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 ARG 100 100 100 ARG ARG A . n 
A 1 101 MET 101 101 101 MET MET A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 HIS 104 104 104 HIS HIS A . n 
A 1 105 ALA 105 105 105 ALA ALA A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 MET 107 107 107 MET MET A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 ILE 109 109 109 ILE ILE A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 GLY 111 111 111 GLY GLY A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 GLN 117 117 117 GLN GLN A . n 
A 1 118 MET 118 118 118 MET MET A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 MET 120 120 120 MET MET A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 THR 123 123 ?   ?   ?   A . n 
A 1 124 GLY 124 124 ?   ?   ?   A . n 
A 1 125 SER 125 125 ?   ?   ?   A . n 
A 1 126 ASN 126 126 ?   ?   ?   A . n 
A 1 127 ALA 127 127 ?   ?   ?   A . n 
A 1 128 LYS 128 128 ?   ?   ?   A . n 
A 1 129 SER 129 129 ?   ?   ?   A . n 
A 1 130 MET 130 130 ?   ?   ?   A . n 
A 1 131 ASP 131 131 ?   ?   ?   A . n 
A 1 132 LEU 132 132 132 LEU LEU A . n 
A 1 133 GLY 133 133 133 GLY GLY A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 PRO 136 136 136 PRO PRO A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 CYS 139 139 139 CYS CYS A . n 
A 1 140 GLY 140 140 140 GLY GLY A . n 
A 1 141 CYS 141 141 141 CYS CYS A . n 
A 1 142 PRO 142 142 142 PRO PRO A . n 
A 1 143 TYR 143 143 143 TYR TYR A . n 
A 1 144 ILE 144 144 144 ILE ILE A . n 
A 1 145 TYR 145 145 145 TYR TYR A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 ARG 147 147 147 ARG ARG A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 ASN 149 149 149 ASN ASN A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 TYR 151 151 151 TYR TYR A . n 
A 1 152 VAL 152 152 152 VAL VAL A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 ILE 154 154 154 ILE ILE A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 HIS 157 157 157 HIS HIS A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 ALA 159 159 159 ALA ALA A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 ARG 162 162 162 ARG ARG A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 ASN 165 165 165 ASN ASN A . n 
A 1 166 THR 166 166 166 THR THR A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 CYS 169 169 169 CYS CYS A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 THR 171 171 171 THR THR A . n 
A 1 172 GLN 172 172 172 GLN GLN A . n 
A 1 173 GLY 173 173 173 GLY GLY A . n 
A 1 174 SER 174 174 174 SER SER A . n 
A 1 175 GLU 175 175 ?   ?   ?   A . n 
A 1 176 GLY 176 176 ?   ?   ?   A . n 
A 1 177 GLU 177 177 ?   ?   ?   A . n 
A 1 178 ALA 178 178 ?   ?   ?   A . n 
A 1 179 THR 179 179 ?   ?   ?   A . n 
A 1 180 LEU 180 180 ?   ?   ?   A . n 
A 1 181 GLU 181 181 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        AG7 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   AG7 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 AG7 1  201 201 AG7 AG7 A . 
C 3 HOH 1  301 54  HOH HOH A . 
C 3 HOH 2  302 473 HOH HOH A . 
C 3 HOH 3  303 6   HOH HOH A . 
C 3 HOH 4  304 1   HOH HOH A . 
C 3 HOH 5  305 36  HOH HOH A . 
C 3 HOH 6  306 2   HOH HOH A . 
C 3 HOH 7  307 112 HOH HOH A . 
C 3 HOH 8  308 361 HOH HOH A . 
C 3 HOH 9  309 71  HOH HOH A . 
C 3 HOH 10 310 69  HOH HOH A . 
C 3 HOH 11 311 26  HOH HOH A . 
C 3 HOH 12 312 56  HOH HOH A . 
C 3 HOH 13 313 395 HOH HOH A . 
C 3 HOH 14 314 57  HOH HOH A . 
C 3 HOH 15 315 16  HOH HOH A . 
C 3 HOH 16 316 3   HOH HOH A . 
C 3 HOH 17 317 28  HOH HOH A . 
C 3 HOH 18 318 31  HOH HOH A . 
C 3 HOH 19 319 367 HOH HOH A . 
C 3 HOH 20 320 4   HOH HOH A . 
C 3 HOH 21 321 234 HOH HOH A . 
C 3 HOH 22 322 35  HOH HOH A . 
C 3 HOH 23 323 125 HOH HOH A . 
C 3 HOH 24 324 12  HOH HOH A . 
C 3 HOH 25 325 39  HOH HOH A . 
C 3 HOH 26 326 41  HOH HOH A . 
C 3 HOH 27 327 38  HOH HOH A . 
C 3 HOH 28 328 11  HOH HOH A . 
C 3 HOH 29 329 10  HOH HOH A . 
C 3 HOH 30 330 536 HOH HOH A . 
C 3 HOH 31 331 55  HOH HOH A . 
C 3 HOH 32 332 7   HOH HOH A . 
C 3 HOH 33 333 18  HOH HOH A . 
C 3 HOH 34 334 80  HOH HOH A . 
C 3 HOH 35 335 681 HOH HOH A . 
C 3 HOH 36 336 96  HOH HOH A . 
C 3 HOH 37 337 184 HOH HOH A . 
C 3 HOH 38 338 663 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.21rc1_5156 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .            2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .            3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .            4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9DA0 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     93.100 
_cell.length_a_esd                 ? 
_cell.length_b                     93.100 
_cell.length_b_esd                 ? 
_cell.length_c                     44.660 
_cell.length_c_esd                 ? 
_cell.volume                       335234.504 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9DA0 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9DA0 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.91 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          57.69 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.9 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M Lithium acetate dihydrate, 20% w/v Polyethylene glycol 3,350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 2M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-07-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9774 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALS BEAMLINE 5.0.1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9774 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   5.0.1 
_diffrn_source.pdbx_synchrotron_site       ALS 
# 
_reflns.B_iso_Wilson_estimate                          41.62 
_reflns.entry_id                                       9DA0 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.28 
_reflns.d_resolution_low                               46.55 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     13538 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           92.03 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.47 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.1105 
_reflns.pdbx_Rpim_I_all                                0.03333 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   1 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.1053 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.28 
_reflns_shell.d_res_low                                     2.61 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.27 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4067 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               10.8 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.647 
_reflns_shell.pdbx_CC_star                                  0.886 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               46.19 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9DA0 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.28 
_refine.ls_d_res_low                             46.55 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     9589 
_refine.ls_number_reflns_R_free                  480 
_refine.ls_number_reflns_R_work                  9109 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    92.03 
_refine.ls_percent_reflns_R_free                 5.01 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2002 
_refine.ls_R_factor_R_free                       0.2330 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1985 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.2119 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3071 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.28 
_refine_hist.d_res_low                        46.55 
_refine_hist.number_atoms_solvent             38 
_refine_hist.number_atoms_total               1313 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1232 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         43 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0030  ? 1318 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7145  ? 1788 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0490  ? 198  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0059  ? 227  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.0256 ? 466  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.28 2.61  . . 170 3240 100.00 . . . . 0.2614 . . . . . . . . . . . 0.2628 
'X-RAY DIFFRACTION' 2.61 3.29  . . 150 2869 87.51  . . . . 0.2394 . . . . . . . . . . . 0.2935 
'X-RAY DIFFRACTION' 3.29 46.55 . . 160 3000 88.79  . . . . 0.1665 . . . . . . . . . . . 0.2002 
# 
_struct.entry_id                     9DA0 
_struct.title                        'Human norovirus GII.4 Houston R112A mutant protease in complex with rupintrivir' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9DA0 
_struct_keywords.text            'Viral protease with inhibitor, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A7S9NT71_9CALI 
_struct_ref.pdbx_db_accession          A0A7S9NT71 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEATLE
;
_struct_ref.pdbx_align_begin           950 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9DA0 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 181 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A7S9NT71 
_struct_ref_seq.db_align_beg                  950 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1130 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       181 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9DA0 
_struct_ref_seq_dif.mon_id                       ALA 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      112 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   A0A7S9NT71 
_struct_ref_seq_dif.db_mon_id                    ARG 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          1061 
_struct_ref_seq_dif.details                      'engineered mutation' 
_struct_ref_seq_dif.pdbx_auth_seq_num            112 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 PRO A 2   ? SER A 7   ? PRO A 2   SER A 7   1 ? 6 
HELX_P HELX_P2 AA2 LYS A 45  ? ILE A 47  ? LYS A 45  ILE A 47  5 ? 3 
HELX_P HELX_P3 AA3 THR A 135 ? CYS A 139 ? THR A 135 CYS A 139 5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 9   ? PHE A 12  ? ILE A 9   PHE A 12  
AA1 2 GLY A 15  ? TRP A 19  ? GLY A 15  TRP A 19  
AA1 3 LEU A 24  ? SER A 28  ? LEU A 24  SER A 28  
AA1 4 PHE A 55  ? ARG A 59  ? PHE A 55  ARG A 59  
AA1 5 GLN A 48  ? SER A 52  ? GLN A 48  SER A 52  
AA2 1 GLU A 38  ? PHE A 39  ? GLU A 38  PHE A 39  
AA2 2 VAL A 42  ? PRO A 43  ? VAL A 42  PRO A 43  
AA3 1 ILE A 72  ? LEU A 73  ? ILE A 72  LEU A 73  
AA3 2 ASP A 150 ? ALA A 160 ? ASP A 150 ALA A 160 
AA3 3 THR A 166 ? ALA A 170 ? THR A 166 ALA A 170 
AA3 4 ALA A 112 ? LEU A 121 ? ALA A 112 LEU A 121 
AA3 5 LEU A 94  ? ILE A 109 ? LEU A 94  ILE A 109 
AA3 6 VAL A 82  ? LYS A 88  ? VAL A 82  LYS A 88  
AA3 7 PRO A 142 ? ARG A 147 ? PRO A 142 ARG A 147 
AA3 8 ASP A 150 ? ALA A 160 ? ASP A 150 ALA A 160 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 10  ? N VAL A 10  O GLY A 17  ? O GLY A 17  
AA1 2 3 N PHE A 18  ? N PHE A 18  O ILE A 26  ? O ILE A 26  
AA1 3 4 N THR A 27  ? N THR A 27  O CYS A 56  ? O CYS A 56  
AA1 4 5 O ARG A 57  ? O ARG A 57  N HIS A 50  ? N HIS A 50  
AA2 1 2 N PHE A 39  ? N PHE A 39  O VAL A 42  ? O VAL A 42  
AA3 1 2 N ILE A 72  ? N ILE A 72  O VAL A 153 ? O VAL A 153 
AA3 2 3 N ALA A 159 ? N ALA A 159 O ILE A 168 ? O ILE A 168 
AA3 3 4 O VAL A 167 ? O VAL A 167 N GLY A 119 ? N GLY A 119 
AA3 4 5 O MET A 118 ? O MET A 118 N GLY A 102 ? N GLY A 102 
AA3 5 6 O LEU A 97  ? O LEU A 97  N LEU A 85  ? N LEU A 85  
AA3 6 7 N THR A 84  ? N THR A 84  O ILE A 144 ? O ILE A 144 
AA3 7 8 N TYR A 145 ? N TYR A 145 O VAL A 152 ? O VAL A 152 
# 
_pdbx_entry_details.entry_id                   9DA0 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined 24.9785699686 27.8369069763 6.13906699771  0.251190284434 ? 0.0064158580049  ? -0.0334620984784  ? 
0.32037959897  ? 0.0455091457691   ? 0.345235504303 ? 5.65234571384 ? -0.443653964894 ? -1.15536914355  ? 6.80830240783 ? 
0.918508911815  ? 5.8556567116   ? -0.197601182205 ? -0.174897085227  ? 0.0187791947247 ? -0.196810812344  ? 0.17075845059   ? 
0.603275507182  ? -0.014047586123  ? -0.0970080234488 ? 0.0859988997476  ? 
2 'X-RAY DIFFRACTION' ? refined 33.8936512873 28.7435458183 12.5797345033  0.336056302118 ? 0.0218534731406  ? -0.00668295533628 ? 
0.445140621911 ? 0.0333884846082   ? 0.342545060435 ? 4.2049652255  ? -5.09246945239  ? -6.11275476913  ? 7.51870791365 ? 
6.8151277452    ? 9.49268343836  ? 0.312260196437  ? -0.222936602509  ? 0.0973127328083 ? -0.0276255907952 ? 0.0261133875997 ? 
-0.291469491915 ? -0.0848654299116 ? -0.184037419061  ? -0.46900303817   ? 
3 'X-RAY DIFFRACTION' ? refined 19.933224187  23.9322396543 15.5262002131  0.317292108777 ? 0.034297541315   ? 0.121108290168    ? 
0.553445158014 ? -0.0179166273089  ? 0.358843511606 ? 6.07931831866 ? 3.38518595147   ? 1.43357738567   ? 7.92914875567 ? 
1.97862254073   ? 7.42286274568  ? 0.17290692584   ? -0.613678492976  ? 0.100802426428  ? 0.5784056209     ? -0.36725039724  ? 
1.00078110908   ? 0.128165574735   ? -1.50253878631   ? 0.298879221447   ? 
4 'X-RAY DIFFRACTION' ? refined 27.9046122327 16.5582820398 -1.35269153743 0.320360338533 ? -0.0701063889001 ? -0.0515027068702  ? 
0.258991527855 ? -0.0180807541967  ? 0.366679744376 ? 6.18540455008 ? -4.35974602584  ? -0.702768973728 ? 5.0419945582  ? 
-0.610458569955 ? 1.09256416751  ? 0.278783318502  ? 0.40601209677    ? -0.414454907228 ? -0.22267042508   ? -0.300918891821 ? 
0.18282075423   ? 0.0826275305174  ? 0.121902647102   ? -0.0345076383558 ? 
5 'X-RAY DIFFRACTION' ? refined 37.8126684351 18.7582258502 -5.5970703418  0.355313242623 ? 0.0199091575184  ? 0.0556894437832   ? 
0.34420193873  ? -0.0479873131828  ? 0.222208534439 ? 6.72104475139 ? -1.85618251927  ? 0.686881899695  ? 2.54654884834 ? 
-0.74879866693  ? 0.750677187001 ? 0.273408267485  ? 0.288437931544   ? -0.541462320312 ? -0.328307183264  ? -0.163953282749 ? 
-0.118154920026 ? -0.230919870725  ? 0.157974689835   ? -0.0709062822641 ? 
6 'X-RAY DIFFRACTION' ? refined 28.7748546358 17.22152453   -2.07146102922 0.180578163537 ? 0.00139247742319 ? -0.0399031227838  ? 
0.288063000452 ? -0.0245554773862  ? 0.359740323177 ? 6.0530447934  ? 0.821451154056  ? -0.103901655395 ? 7.89054923201 ? 
-0.258018068748 ? 5.41403834485  ? 0.0808650774093 ? -0.0335406007778 ? -0.325409310139 ? 0.227339941539   ? -0.159184850525 ? 
0.469891889752  ? 0.113132777583   ? -0.215424079223  ? 0.0230544811929  ? 
7 'X-RAY DIFFRACTION' ? refined 37.8640621127 20.5898033467 -5.26155540922 0.430662508183 ? 0.0419908489688  ? 0.0570613648204   ? 
0.273199539948 ? -0.00746423909305 ? 0.391221930092 ? 8.62335523271 ? 1.49281176087   ? -1.90526674625  ? 7.84818473528 ? 
0.0618556848391 ? 2.10809809945  ? -0.4423210074   ? 0.207509061664   ? -0.400695817118 ? -0.567313672126  ? -0.124633023537 ? 
-0.632164800402 ? -0.0765719658862 ? 0.160199449007   ? 0.713330611642   ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 A 1   A 1   ? A 43  A 43  ? ? 
;chain 'A' and (resid 1 through 43 )
;
2 'X-RAY DIFFRACTION' 2 A 44  A 44  ? A 59  A 59  ? ? 
;chain 'A' and (resid 44 through 59 )
;
3 'X-RAY DIFFRACTION' 3 A 60  A 60  ? A 69  A 69  ? ? 
;chain 'A' and (resid 60 through 69 )
;
4 'X-RAY DIFFRACTION' 4 A 70  A 70  ? A 93  A 93  ? ? 
;chain 'A' and (resid 70 through 93 )
;
5 'X-RAY DIFFRACTION' 5 A 94  A 94  ? A 121 A 121 ? ? 
;chain 'A' and (resid 94 through 121 )
;
6 'X-RAY DIFFRACTION' 6 A 122 A 122 ? A 151 A 160 ? ? 
;chain 'A' and (resid 122 through 160 )
;
7 'X-RAY DIFFRACTION' 7 A 152 A 161 ? A 165 A 174 ? ? 
;chain 'A' and (resid 161 through 174 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A THR 123 ? A THR 123 
2  1 Y 1 A GLY 124 ? A GLY 124 
3  1 Y 1 A SER 125 ? A SER 125 
4  1 Y 1 A ASN 126 ? A ASN 126 
5  1 Y 1 A ALA 127 ? A ALA 127 
6  1 Y 1 A LYS 128 ? A LYS 128 
7  1 Y 1 A SER 129 ? A SER 129 
8  1 Y 1 A MET 130 ? A MET 130 
9  1 Y 1 A ASP 131 ? A ASP 131 
10 1 Y 1 A GLU 175 ? A GLU 175 
11 1 Y 1 A GLY 176 ? A GLY 176 
12 1 Y 1 A GLU 177 ? A GLU 177 
13 1 Y 1 A ALA 178 ? A ALA 178 
14 1 Y 1 A THR 179 ? A THR 179 
15 1 Y 1 A LEU 180 ? A LEU 180 
16 1 Y 1 A GLU 181 ? A GLU 181 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
AG7 C01  C N N 1   
AG7 C02  C N N 2   
AG7 O03  O N N 3   
AG7 C04  C N R 4   
AG7 C05  C N N 5   
AG7 C06  C Y N 6   
AG7 C07  C Y N 7   
AG7 C08  C Y N 8   
AG7 C09  C Y N 9   
AG7 C10  C Y N 10  
AG7 C11  C Y N 11  
AG7 N12  N N N 12  
AG7 C13  C N R 13  
AG7 C14  C N N 14  
AG7 C15  C N S 15  
AG7 C16  C N N 16  
AG7 N17  N N N 17  
AG7 O18  O N N 18  
AG7 C19  C N N 19  
AG7 C20  C N N 20  
AG7 C21  C N N 21  
AG7 O22  O N N 22  
AG7 O23  O N N 23  
AG7 C47  C N N 24  
AG7 O48  O N N 25  
AG7 C50  C N N 26  
AG7 C53  C N N 27  
AG7 C57  C N S 28  
AG7 N58  N N N 29  
AG7 C59  C N N 30  
AG7 O60  O N N 31  
AG7 C78  C N N 32  
AG7 C81  C N N 33  
AG7 F1   F N N 34  
AG7 C82  C N N 35  
AG7 C83  C N N 36  
AG7 C84  C N N 37  
AG7 C1   C Y N 38  
AG7 C2   C Y N 39  
AG7 C3   C Y N 40  
AG7 O4   O Y N 41  
AG7 N5   N Y N 42  
AG7 C4   C N N 43  
AG7 H2   H N N 44  
AG7 H3   H N N 45  
AG7 H27  H N N 46  
AG7 H28  H N N 47  
AG7 H29  H N N 48  
AG7 H30  H N N 49  
AG7 H31  H N N 50  
AG7 H33  H N N 51  
AG7 H34  H N N 52  
AG7 H49  H N N 53  
AG7 H91  H N N 54  
AG7 H35  H N N 55  
AG7 H36  H N N 56  
AG7 H94  H N N 57  
AG7 H39  H N N 58  
AG7 H191 H N N 59  
AG7 H192 H N N 60  
AG7 H41  H N N 61  
AG7 H42  H N N 62  
AG7 H51  H N N 63  
AG7 H52  H N N 64  
AG7 H53  H N N 65  
AG7 H54  H N N 66  
AG7 H56  H N N 67  
AG7 H77  H N N 68  
AG7 H61  H N N 69  
AG7 H79  H N N 70  
AG7 H82  H N N 71  
AG7 H84  H N N 72  
AG7 H85  H N N 73  
AG7 H86  H N N 74  
AG7 H87  H N N 75  
AG7 H88  H N N 76  
AG7 H89  H N N 77  
AG7 H90  H N N 78  
AG7 H92  H N N 79  
AG7 H93  H N N 80  
AG7 H8   H N N 81  
AG7 H5   H N N 82  
AG7 H6   H N N 83  
AG7 H7   H N N 84  
ALA N    N N N 85  
ALA CA   C N S 86  
ALA C    C N N 87  
ALA O    O N N 88  
ALA CB   C N N 89  
ALA OXT  O N N 90  
ALA H    H N N 91  
ALA H2   H N N 92  
ALA HA   H N N 93  
ALA HB1  H N N 94  
ALA HB2  H N N 95  
ALA HB3  H N N 96  
ALA HXT  H N N 97  
ARG N    N N N 98  
ARG CA   C N S 99  
ARG C    C N N 100 
ARG O    O N N 101 
ARG CB   C N N 102 
ARG CG   C N N 103 
ARG CD   C N N 104 
ARG NE   N N N 105 
ARG CZ   C N N 106 
ARG NH1  N N N 107 
ARG NH2  N N N 108 
ARG OXT  O N N 109 
ARG H    H N N 110 
ARG H2   H N N 111 
ARG HA   H N N 112 
ARG HB2  H N N 113 
ARG HB3  H N N 114 
ARG HG2  H N N 115 
ARG HG3  H N N 116 
ARG HD2  H N N 117 
ARG HD3  H N N 118 
ARG HE   H N N 119 
ARG HH11 H N N 120 
ARG HH12 H N N 121 
ARG HH21 H N N 122 
ARG HH22 H N N 123 
ARG HXT  H N N 124 
ASN N    N N N 125 
ASN CA   C N S 126 
ASN C    C N N 127 
ASN O    O N N 128 
ASN CB   C N N 129 
ASN CG   C N N 130 
ASN OD1  O N N 131 
ASN ND2  N N N 132 
ASN OXT  O N N 133 
ASN H    H N N 134 
ASN H2   H N N 135 
ASN HA   H N N 136 
ASN HB2  H N N 137 
ASN HB3  H N N 138 
ASN HD21 H N N 139 
ASN HD22 H N N 140 
ASN HXT  H N N 141 
ASP N    N N N 142 
ASP CA   C N S 143 
ASP C    C N N 144 
ASP O    O N N 145 
ASP CB   C N N 146 
ASP CG   C N N 147 
ASP OD1  O N N 148 
ASP OD2  O N N 149 
ASP OXT  O N N 150 
ASP H    H N N 151 
ASP H2   H N N 152 
ASP HA   H N N 153 
ASP HB2  H N N 154 
ASP HB3  H N N 155 
ASP HD2  H N N 156 
ASP HXT  H N N 157 
CYS N    N N N 158 
CYS CA   C N R 159 
CYS C    C N N 160 
CYS O    O N N 161 
CYS CB   C N N 162 
CYS SG   S N N 163 
CYS OXT  O N N 164 
CYS H    H N N 165 
CYS H2   H N N 166 
CYS HA   H N N 167 
CYS HB2  H N N 168 
CYS HB3  H N N 169 
CYS HG   H N N 170 
CYS HXT  H N N 171 
GLN N    N N N 172 
GLN CA   C N S 173 
GLN C    C N N 174 
GLN O    O N N 175 
GLN CB   C N N 176 
GLN CG   C N N 177 
GLN CD   C N N 178 
GLN OE1  O N N 179 
GLN NE2  N N N 180 
GLN OXT  O N N 181 
GLN H    H N N 182 
GLN H2   H N N 183 
GLN HA   H N N 184 
GLN HB2  H N N 185 
GLN HB3  H N N 186 
GLN HG2  H N N 187 
GLN HG3  H N N 188 
GLN HE21 H N N 189 
GLN HE22 H N N 190 
GLN HXT  H N N 191 
GLU N    N N N 192 
GLU CA   C N S 193 
GLU C    C N N 194 
GLU O    O N N 195 
GLU CB   C N N 196 
GLU CG   C N N 197 
GLU CD   C N N 198 
GLU OE1  O N N 199 
GLU OE2  O N N 200 
GLU OXT  O N N 201 
GLU H    H N N 202 
GLU H2   H N N 203 
GLU HA   H N N 204 
GLU HB2  H N N 205 
GLU HB3  H N N 206 
GLU HG2  H N N 207 
GLU HG3  H N N 208 
GLU HE2  H N N 209 
GLU HXT  H N N 210 
GLY N    N N N 211 
GLY CA   C N N 212 
GLY C    C N N 213 
GLY O    O N N 214 
GLY OXT  O N N 215 
GLY H    H N N 216 
GLY H2   H N N 217 
GLY HA2  H N N 218 
GLY HA3  H N N 219 
GLY HXT  H N N 220 
HIS N    N N N 221 
HIS CA   C N S 222 
HIS C    C N N 223 
HIS O    O N N 224 
HIS CB   C N N 225 
HIS CG   C Y N 226 
HIS ND1  N Y N 227 
HIS CD2  C Y N 228 
HIS CE1  C Y N 229 
HIS NE2  N Y N 230 
HIS OXT  O N N 231 
HIS H    H N N 232 
HIS H2   H N N 233 
HIS HA   H N N 234 
HIS HB2  H N N 235 
HIS HB3  H N N 236 
HIS HD1  H N N 237 
HIS HD2  H N N 238 
HIS HE1  H N N 239 
HIS HE2  H N N 240 
HIS HXT  H N N 241 
HOH O    O N N 242 
HOH H1   H N N 243 
HOH H2   H N N 244 
ILE N    N N N 245 
ILE CA   C N S 246 
ILE C    C N N 247 
ILE O    O N N 248 
ILE CB   C N S 249 
ILE CG1  C N N 250 
ILE CG2  C N N 251 
ILE CD1  C N N 252 
ILE OXT  O N N 253 
ILE H    H N N 254 
ILE H2   H N N 255 
ILE HA   H N N 256 
ILE HB   H N N 257 
ILE HG12 H N N 258 
ILE HG13 H N N 259 
ILE HG21 H N N 260 
ILE HG22 H N N 261 
ILE HG23 H N N 262 
ILE HD11 H N N 263 
ILE HD12 H N N 264 
ILE HD13 H N N 265 
ILE HXT  H N N 266 
LEU N    N N N 267 
LEU CA   C N S 268 
LEU C    C N N 269 
LEU O    O N N 270 
LEU CB   C N N 271 
LEU CG   C N N 272 
LEU CD1  C N N 273 
LEU CD2  C N N 274 
LEU OXT  O N N 275 
LEU H    H N N 276 
LEU H2   H N N 277 
LEU HA   H N N 278 
LEU HB2  H N N 279 
LEU HB3  H N N 280 
LEU HG   H N N 281 
LEU HD11 H N N 282 
LEU HD12 H N N 283 
LEU HD13 H N N 284 
LEU HD21 H N N 285 
LEU HD22 H N N 286 
LEU HD23 H N N 287 
LEU HXT  H N N 288 
LYS N    N N N 289 
LYS CA   C N S 290 
LYS C    C N N 291 
LYS O    O N N 292 
LYS CB   C N N 293 
LYS CG   C N N 294 
LYS CD   C N N 295 
LYS CE   C N N 296 
LYS NZ   N N N 297 
LYS OXT  O N N 298 
LYS H    H N N 299 
LYS H2   H N N 300 
LYS HA   H N N 301 
LYS HB2  H N N 302 
LYS HB3  H N N 303 
LYS HG2  H N N 304 
LYS HG3  H N N 305 
LYS HD2  H N N 306 
LYS HD3  H N N 307 
LYS HE2  H N N 308 
LYS HE3  H N N 309 
LYS HZ1  H N N 310 
LYS HZ2  H N N 311 
LYS HZ3  H N N 312 
LYS HXT  H N N 313 
MET N    N N N 314 
MET CA   C N S 315 
MET C    C N N 316 
MET O    O N N 317 
MET CB   C N N 318 
MET CG   C N N 319 
MET SD   S N N 320 
MET CE   C N N 321 
MET OXT  O N N 322 
MET H    H N N 323 
MET H2   H N N 324 
MET HA   H N N 325 
MET HB2  H N N 326 
MET HB3  H N N 327 
MET HG2  H N N 328 
MET HG3  H N N 329 
MET HE1  H N N 330 
MET HE2  H N N 331 
MET HE3  H N N 332 
MET HXT  H N N 333 
PHE N    N N N 334 
PHE CA   C N S 335 
PHE C    C N N 336 
PHE O    O N N 337 
PHE CB   C N N 338 
PHE CG   C Y N 339 
PHE CD1  C Y N 340 
PHE CD2  C Y N 341 
PHE CE1  C Y N 342 
PHE CE2  C Y N 343 
PHE CZ   C Y N 344 
PHE OXT  O N N 345 
PHE H    H N N 346 
PHE H2   H N N 347 
PHE HA   H N N 348 
PHE HB2  H N N 349 
PHE HB3  H N N 350 
PHE HD1  H N N 351 
PHE HD2  H N N 352 
PHE HE1  H N N 353 
PHE HE2  H N N 354 
PHE HZ   H N N 355 
PHE HXT  H N N 356 
PRO N    N N N 357 
PRO CA   C N S 358 
PRO C    C N N 359 
PRO O    O N N 360 
PRO CB   C N N 361 
PRO CG   C N N 362 
PRO CD   C N N 363 
PRO OXT  O N N 364 
PRO H    H N N 365 
PRO HA   H N N 366 
PRO HB2  H N N 367 
PRO HB3  H N N 368 
PRO HG2  H N N 369 
PRO HG3  H N N 370 
PRO HD2  H N N 371 
PRO HD3  H N N 372 
PRO HXT  H N N 373 
SER N    N N N 374 
SER CA   C N S 375 
SER C    C N N 376 
SER O    O N N 377 
SER CB   C N N 378 
SER OG   O N N 379 
SER OXT  O N N 380 
SER H    H N N 381 
SER H2   H N N 382 
SER HA   H N N 383 
SER HB2  H N N 384 
SER HB3  H N N 385 
SER HG   H N N 386 
SER HXT  H N N 387 
THR N    N N N 388 
THR CA   C N S 389 
THR C    C N N 390 
THR O    O N N 391 
THR CB   C N R 392 
THR OG1  O N N 393 
THR CG2  C N N 394 
THR OXT  O N N 395 
THR H    H N N 396 
THR H2   H N N 397 
THR HA   H N N 398 
THR HB   H N N 399 
THR HG1  H N N 400 
THR HG21 H N N 401 
THR HG22 H N N 402 
THR HG23 H N N 403 
THR HXT  H N N 404 
TRP N    N N N 405 
TRP CA   C N S 406 
TRP C    C N N 407 
TRP O    O N N 408 
TRP CB   C N N 409 
TRP CG   C Y N 410 
TRP CD1  C Y N 411 
TRP CD2  C Y N 412 
TRP NE1  N Y N 413 
TRP CE2  C Y N 414 
TRP CE3  C Y N 415 
TRP CZ2  C Y N 416 
TRP CZ3  C Y N 417 
TRP CH2  C Y N 418 
TRP OXT  O N N 419 
TRP H    H N N 420 
TRP H2   H N N 421 
TRP HA   H N N 422 
TRP HB2  H N N 423 
TRP HB3  H N N 424 
TRP HD1  H N N 425 
TRP HE1  H N N 426 
TRP HE3  H N N 427 
TRP HZ2  H N N 428 
TRP HZ3  H N N 429 
TRP HH2  H N N 430 
TRP HXT  H N N 431 
TYR N    N N N 432 
TYR CA   C N S 433 
TYR C    C N N 434 
TYR O    O N N 435 
TYR CB   C N N 436 
TYR CG   C Y N 437 
TYR CD1  C Y N 438 
TYR CD2  C Y N 439 
TYR CE1  C Y N 440 
TYR CE2  C Y N 441 
TYR CZ   C Y N 442 
TYR OH   O N N 443 
TYR OXT  O N N 444 
TYR H    H N N 445 
TYR H2   H N N 446 
TYR HA   H N N 447 
TYR HB2  H N N 448 
TYR HB3  H N N 449 
TYR HD1  H N N 450 
TYR HD2  H N N 451 
TYR HE1  H N N 452 
TYR HE2  H N N 453 
TYR HH   H N N 454 
TYR HXT  H N N 455 
VAL N    N N N 456 
VAL CA   C N S 457 
VAL C    C N N 458 
VAL O    O N N 459 
VAL CB   C N N 460 
VAL CG1  C N N 461 
VAL CG2  C N N 462 
VAL OXT  O N N 463 
VAL H    H N N 464 
VAL H2   H N N 465 
VAL HA   H N N 466 
VAL HB   H N N 467 
VAL HG11 H N N 468 
VAL HG12 H N N 469 
VAL HG13 H N N 470 
VAL HG21 H N N 471 
VAL HG22 H N N 472 
VAL HG23 H N N 473 
VAL HXT  H N N 474 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
AG7 C01 C02  sing N N 1   
AG7 C01 O03  doub N N 2   
AG7 C01 C57  sing N N 3   
AG7 C02 C04  sing N N 4   
AG7 C02 H2   sing N N 5   
AG7 C02 H3   sing N N 6   
AG7 C04 C05  sing N N 7   
AG7 C04 C47  sing N N 8   
AG7 C04 H27  sing N N 9   
AG7 C05 C06  sing N N 10  
AG7 C05 H28  sing N N 11  
AG7 C05 H29  sing N N 12  
AG7 C06 C07  doub Y N 13  
AG7 C06 C11  sing Y N 14  
AG7 C07 C08  sing Y N 15  
AG7 C07 H30  sing N N 16  
AG7 C08 C09  doub Y N 17  
AG7 C08 H31  sing N N 18  
AG7 C09 C10  sing Y N 19  
AG7 C09 F1   sing N N 20  
AG7 C10 C11  doub Y N 21  
AG7 C10 H33  sing N N 22  
AG7 C11 H34  sing N N 23  
AG7 N12 C13  sing N N 24  
AG7 N12 C47  sing N N 25  
AG7 N12 H49  sing N N 26  
AG7 C13 C14  sing N N 27  
AG7 C13 C19  sing N N 28  
AG7 C13 H91  sing N N 29  
AG7 C14 C15  sing N N 30  
AG7 C14 H35  sing N N 31  
AG7 C14 H36  sing N N 32  
AG7 C15 C16  sing N N 33  
AG7 C15 C84  sing N N 34  
AG7 C15 H94  sing N N 35  
AG7 C16 N17  sing N N 36  
AG7 C16 O18  doub N N 37  
AG7 N17 C83  sing N N 38  
AG7 N17 H39  sing N N 39  
AG7 C19 C20  sing N N 40  
AG7 C19 H191 sing N N 41  
AG7 C19 H192 sing N N 42  
AG7 C20 C21  sing N N 43  
AG7 C20 H41  sing N N 44  
AG7 C20 H42  sing N N 45  
AG7 C21 O22  sing N N 46  
AG7 C21 O23  doub N N 47  
AG7 O22 C50  sing N N 48  
AG7 C47 O48  doub N N 49  
AG7 C50 C53  sing N N 50  
AG7 C50 H51  sing N N 51  
AG7 C50 H52  sing N N 52  
AG7 C53 H53  sing N N 53  
AG7 C53 H54  sing N N 54  
AG7 C53 H56  sing N N 55  
AG7 C57 N58  sing N N 56  
AG7 C57 C78  sing N N 57  
AG7 C57 H77  sing N N 58  
AG7 N58 C59  sing N N 59  
AG7 N58 H61  sing N N 60  
AG7 C59 O60  doub N N 61  
AG7 C59 C1   sing N N 62  
AG7 C78 C81  sing N N 63  
AG7 C78 C82  sing N N 64  
AG7 C78 H79  sing N N 65  
AG7 C81 H82  sing N N 66  
AG7 C81 H84  sing N N 67  
AG7 C81 H85  sing N N 68  
AG7 C82 H86  sing N N 69  
AG7 C82 H87  sing N N 70  
AG7 C82 H88  sing N N 71  
AG7 C83 C84  sing N N 72  
AG7 C83 H89  sing N N 73  
AG7 C83 H90  sing N N 74  
AG7 C84 H92  sing N N 75  
AG7 C84 H93  sing N N 76  
AG7 C1  C2   sing Y N 77  
AG7 C1  N5   doub Y N 78  
AG7 C2  C3   doub Y N 79  
AG7 C2  H8   sing N N 80  
AG7 C3  O4   sing Y N 81  
AG7 C3  C4   sing N N 82  
AG7 O4  N5   sing Y N 83  
AG7 C4  H5   sing N N 84  
AG7 C4  H6   sing N N 85  
AG7 C4  H7   sing N N 86  
ALA N   CA   sing N N 87  
ALA N   H    sing N N 88  
ALA N   H2   sing N N 89  
ALA CA  C    sing N N 90  
ALA CA  CB   sing N N 91  
ALA CA  HA   sing N N 92  
ALA C   O    doub N N 93  
ALA C   OXT  sing N N 94  
ALA CB  HB1  sing N N 95  
ALA CB  HB2  sing N N 96  
ALA CB  HB3  sing N N 97  
ALA OXT HXT  sing N N 98  
ARG N   CA   sing N N 99  
ARG N   H    sing N N 100 
ARG N   H2   sing N N 101 
ARG CA  C    sing N N 102 
ARG CA  CB   sing N N 103 
ARG CA  HA   sing N N 104 
ARG C   O    doub N N 105 
ARG C   OXT  sing N N 106 
ARG CB  CG   sing N N 107 
ARG CB  HB2  sing N N 108 
ARG CB  HB3  sing N N 109 
ARG CG  CD   sing N N 110 
ARG CG  HG2  sing N N 111 
ARG CG  HG3  sing N N 112 
ARG CD  NE   sing N N 113 
ARG CD  HD2  sing N N 114 
ARG CD  HD3  sing N N 115 
ARG NE  CZ   sing N N 116 
ARG NE  HE   sing N N 117 
ARG CZ  NH1  sing N N 118 
ARG CZ  NH2  doub N N 119 
ARG NH1 HH11 sing N N 120 
ARG NH1 HH12 sing N N 121 
ARG NH2 HH21 sing N N 122 
ARG NH2 HH22 sing N N 123 
ARG OXT HXT  sing N N 124 
ASN N   CA   sing N N 125 
ASN N   H    sing N N 126 
ASN N   H2   sing N N 127 
ASN CA  C    sing N N 128 
ASN CA  CB   sing N N 129 
ASN CA  HA   sing N N 130 
ASN C   O    doub N N 131 
ASN C   OXT  sing N N 132 
ASN CB  CG   sing N N 133 
ASN CB  HB2  sing N N 134 
ASN CB  HB3  sing N N 135 
ASN CG  OD1  doub N N 136 
ASN CG  ND2  sing N N 137 
ASN ND2 HD21 sing N N 138 
ASN ND2 HD22 sing N N 139 
ASN OXT HXT  sing N N 140 
ASP N   CA   sing N N 141 
ASP N   H    sing N N 142 
ASP N   H2   sing N N 143 
ASP CA  C    sing N N 144 
ASP CA  CB   sing N N 145 
ASP CA  HA   sing N N 146 
ASP C   O    doub N N 147 
ASP C   OXT  sing N N 148 
ASP CB  CG   sing N N 149 
ASP CB  HB2  sing N N 150 
ASP CB  HB3  sing N N 151 
ASP CG  OD1  doub N N 152 
ASP CG  OD2  sing N N 153 
ASP OD2 HD2  sing N N 154 
ASP OXT HXT  sing N N 155 
CYS N   CA   sing N N 156 
CYS N   H    sing N N 157 
CYS N   H2   sing N N 158 
CYS CA  C    sing N N 159 
CYS CA  CB   sing N N 160 
CYS CA  HA   sing N N 161 
CYS C   O    doub N N 162 
CYS C   OXT  sing N N 163 
CYS CB  SG   sing N N 164 
CYS CB  HB2  sing N N 165 
CYS CB  HB3  sing N N 166 
CYS SG  HG   sing N N 167 
CYS OXT HXT  sing N N 168 
GLN N   CA   sing N N 169 
GLN N   H    sing N N 170 
GLN N   H2   sing N N 171 
GLN CA  C    sing N N 172 
GLN CA  CB   sing N N 173 
GLN CA  HA   sing N N 174 
GLN C   O    doub N N 175 
GLN C   OXT  sing N N 176 
GLN CB  CG   sing N N 177 
GLN CB  HB2  sing N N 178 
GLN CB  HB3  sing N N 179 
GLN CG  CD   sing N N 180 
GLN CG  HG2  sing N N 181 
GLN CG  HG3  sing N N 182 
GLN CD  OE1  doub N N 183 
GLN CD  NE2  sing N N 184 
GLN NE2 HE21 sing N N 185 
GLN NE2 HE22 sing N N 186 
GLN OXT HXT  sing N N 187 
GLU N   CA   sing N N 188 
GLU N   H    sing N N 189 
GLU N   H2   sing N N 190 
GLU CA  C    sing N N 191 
GLU CA  CB   sing N N 192 
GLU CA  HA   sing N N 193 
GLU C   O    doub N N 194 
GLU C   OXT  sing N N 195 
GLU CB  CG   sing N N 196 
GLU CB  HB2  sing N N 197 
GLU CB  HB3  sing N N 198 
GLU CG  CD   sing N N 199 
GLU CG  HG2  sing N N 200 
GLU CG  HG3  sing N N 201 
GLU CD  OE1  doub N N 202 
GLU CD  OE2  sing N N 203 
GLU OE2 HE2  sing N N 204 
GLU OXT HXT  sing N N 205 
GLY N   CA   sing N N 206 
GLY N   H    sing N N 207 
GLY N   H2   sing N N 208 
GLY CA  C    sing N N 209 
GLY CA  HA2  sing N N 210 
GLY CA  HA3  sing N N 211 
GLY C   O    doub N N 212 
GLY C   OXT  sing N N 213 
GLY OXT HXT  sing N N 214 
HIS N   CA   sing N N 215 
HIS N   H    sing N N 216 
HIS N   H2   sing N N 217 
HIS CA  C    sing N N 218 
HIS CA  CB   sing N N 219 
HIS CA  HA   sing N N 220 
HIS C   O    doub N N 221 
HIS C   OXT  sing N N 222 
HIS CB  CG   sing N N 223 
HIS CB  HB2  sing N N 224 
HIS CB  HB3  sing N N 225 
HIS CG  ND1  sing Y N 226 
HIS CG  CD2  doub Y N 227 
HIS ND1 CE1  doub Y N 228 
HIS ND1 HD1  sing N N 229 
HIS CD2 NE2  sing Y N 230 
HIS CD2 HD2  sing N N 231 
HIS CE1 NE2  sing Y N 232 
HIS CE1 HE1  sing N N 233 
HIS NE2 HE2  sing N N 234 
HIS OXT HXT  sing N N 235 
HOH O   H1   sing N N 236 
HOH O   H2   sing N N 237 
ILE N   CA   sing N N 238 
ILE N   H    sing N N 239 
ILE N   H2   sing N N 240 
ILE CA  C    sing N N 241 
ILE CA  CB   sing N N 242 
ILE CA  HA   sing N N 243 
ILE C   O    doub N N 244 
ILE C   OXT  sing N N 245 
ILE CB  CG1  sing N N 246 
ILE CB  CG2  sing N N 247 
ILE CB  HB   sing N N 248 
ILE CG1 CD1  sing N N 249 
ILE CG1 HG12 sing N N 250 
ILE CG1 HG13 sing N N 251 
ILE CG2 HG21 sing N N 252 
ILE CG2 HG22 sing N N 253 
ILE CG2 HG23 sing N N 254 
ILE CD1 HD11 sing N N 255 
ILE CD1 HD12 sing N N 256 
ILE CD1 HD13 sing N N 257 
ILE OXT HXT  sing N N 258 
LEU N   CA   sing N N 259 
LEU N   H    sing N N 260 
LEU N   H2   sing N N 261 
LEU CA  C    sing N N 262 
LEU CA  CB   sing N N 263 
LEU CA  HA   sing N N 264 
LEU C   O    doub N N 265 
LEU C   OXT  sing N N 266 
LEU CB  CG   sing N N 267 
LEU CB  HB2  sing N N 268 
LEU CB  HB3  sing N N 269 
LEU CG  CD1  sing N N 270 
LEU CG  CD2  sing N N 271 
LEU CG  HG   sing N N 272 
LEU CD1 HD11 sing N N 273 
LEU CD1 HD12 sing N N 274 
LEU CD1 HD13 sing N N 275 
LEU CD2 HD21 sing N N 276 
LEU CD2 HD22 sing N N 277 
LEU CD2 HD23 sing N N 278 
LEU OXT HXT  sing N N 279 
LYS N   CA   sing N N 280 
LYS N   H    sing N N 281 
LYS N   H2   sing N N 282 
LYS CA  C    sing N N 283 
LYS CA  CB   sing N N 284 
LYS CA  HA   sing N N 285 
LYS C   O    doub N N 286 
LYS C   OXT  sing N N 287 
LYS CB  CG   sing N N 288 
LYS CB  HB2  sing N N 289 
LYS CB  HB3  sing N N 290 
LYS CG  CD   sing N N 291 
LYS CG  HG2  sing N N 292 
LYS CG  HG3  sing N N 293 
LYS CD  CE   sing N N 294 
LYS CD  HD2  sing N N 295 
LYS CD  HD3  sing N N 296 
LYS CE  NZ   sing N N 297 
LYS CE  HE2  sing N N 298 
LYS CE  HE3  sing N N 299 
LYS NZ  HZ1  sing N N 300 
LYS NZ  HZ2  sing N N 301 
LYS NZ  HZ3  sing N N 302 
LYS OXT HXT  sing N N 303 
MET N   CA   sing N N 304 
MET N   H    sing N N 305 
MET N   H2   sing N N 306 
MET CA  C    sing N N 307 
MET CA  CB   sing N N 308 
MET CA  HA   sing N N 309 
MET C   O    doub N N 310 
MET C   OXT  sing N N 311 
MET CB  CG   sing N N 312 
MET CB  HB2  sing N N 313 
MET CB  HB3  sing N N 314 
MET CG  SD   sing N N 315 
MET CG  HG2  sing N N 316 
MET CG  HG3  sing N N 317 
MET SD  CE   sing N N 318 
MET CE  HE1  sing N N 319 
MET CE  HE2  sing N N 320 
MET CE  HE3  sing N N 321 
MET OXT HXT  sing N N 322 
PHE N   CA   sing N N 323 
PHE N   H    sing N N 324 
PHE N   H2   sing N N 325 
PHE CA  C    sing N N 326 
PHE CA  CB   sing N N 327 
PHE CA  HA   sing N N 328 
PHE C   O    doub N N 329 
PHE C   OXT  sing N N 330 
PHE CB  CG   sing N N 331 
PHE CB  HB2  sing N N 332 
PHE CB  HB3  sing N N 333 
PHE CG  CD1  doub Y N 334 
PHE CG  CD2  sing Y N 335 
PHE CD1 CE1  sing Y N 336 
PHE CD1 HD1  sing N N 337 
PHE CD2 CE2  doub Y N 338 
PHE CD2 HD2  sing N N 339 
PHE CE1 CZ   doub Y N 340 
PHE CE1 HE1  sing N N 341 
PHE CE2 CZ   sing Y N 342 
PHE CE2 HE2  sing N N 343 
PHE CZ  HZ   sing N N 344 
PHE OXT HXT  sing N N 345 
PRO N   CA   sing N N 346 
PRO N   CD   sing N N 347 
PRO N   H    sing N N 348 
PRO CA  C    sing N N 349 
PRO CA  CB   sing N N 350 
PRO CA  HA   sing N N 351 
PRO C   O    doub N N 352 
PRO C   OXT  sing N N 353 
PRO CB  CG   sing N N 354 
PRO CB  HB2  sing N N 355 
PRO CB  HB3  sing N N 356 
PRO CG  CD   sing N N 357 
PRO CG  HG2  sing N N 358 
PRO CG  HG3  sing N N 359 
PRO CD  HD2  sing N N 360 
PRO CD  HD3  sing N N 361 
PRO OXT HXT  sing N N 362 
SER N   CA   sing N N 363 
SER N   H    sing N N 364 
SER N   H2   sing N N 365 
SER CA  C    sing N N 366 
SER CA  CB   sing N N 367 
SER CA  HA   sing N N 368 
SER C   O    doub N N 369 
SER C   OXT  sing N N 370 
SER CB  OG   sing N N 371 
SER CB  HB2  sing N N 372 
SER CB  HB3  sing N N 373 
SER OG  HG   sing N N 374 
SER OXT HXT  sing N N 375 
THR N   CA   sing N N 376 
THR N   H    sing N N 377 
THR N   H2   sing N N 378 
THR CA  C    sing N N 379 
THR CA  CB   sing N N 380 
THR CA  HA   sing N N 381 
THR C   O    doub N N 382 
THR C   OXT  sing N N 383 
THR CB  OG1  sing N N 384 
THR CB  CG2  sing N N 385 
THR CB  HB   sing N N 386 
THR OG1 HG1  sing N N 387 
THR CG2 HG21 sing N N 388 
THR CG2 HG22 sing N N 389 
THR CG2 HG23 sing N N 390 
THR OXT HXT  sing N N 391 
TRP N   CA   sing N N 392 
TRP N   H    sing N N 393 
TRP N   H2   sing N N 394 
TRP CA  C    sing N N 395 
TRP CA  CB   sing N N 396 
TRP CA  HA   sing N N 397 
TRP C   O    doub N N 398 
TRP C   OXT  sing N N 399 
TRP CB  CG   sing N N 400 
TRP CB  HB2  sing N N 401 
TRP CB  HB3  sing N N 402 
TRP CG  CD1  doub Y N 403 
TRP CG  CD2  sing Y N 404 
TRP CD1 NE1  sing Y N 405 
TRP CD1 HD1  sing N N 406 
TRP CD2 CE2  doub Y N 407 
TRP CD2 CE3  sing Y N 408 
TRP NE1 CE2  sing Y N 409 
TRP NE1 HE1  sing N N 410 
TRP CE2 CZ2  sing Y N 411 
TRP CE3 CZ3  doub Y N 412 
TRP CE3 HE3  sing N N 413 
TRP CZ2 CH2  doub Y N 414 
TRP CZ2 HZ2  sing N N 415 
TRP CZ3 CH2  sing Y N 416 
TRP CZ3 HZ3  sing N N 417 
TRP CH2 HH2  sing N N 418 
TRP OXT HXT  sing N N 419 
TYR N   CA   sing N N 420 
TYR N   H    sing N N 421 
TYR N   H2   sing N N 422 
TYR CA  C    sing N N 423 
TYR CA  CB   sing N N 424 
TYR CA  HA   sing N N 425 
TYR C   O    doub N N 426 
TYR C   OXT  sing N N 427 
TYR CB  CG   sing N N 428 
TYR CB  HB2  sing N N 429 
TYR CB  HB3  sing N N 430 
TYR CG  CD1  doub Y N 431 
TYR CG  CD2  sing Y N 432 
TYR CD1 CE1  sing Y N 433 
TYR CD1 HD1  sing N N 434 
TYR CD2 CE2  doub Y N 435 
TYR CD2 HD2  sing N N 436 
TYR CE1 CZ   doub Y N 437 
TYR CE1 HE1  sing N N 438 
TYR CE2 CZ   sing Y N 439 
TYR CE2 HE2  sing N N 440 
TYR CZ  OH   sing N N 441 
TYR OH  HH   sing N N 442 
TYR OXT HXT  sing N N 443 
VAL N   CA   sing N N 444 
VAL N   H    sing N N 445 
VAL N   H2   sing N N 446 
VAL CA  C    sing N N 447 
VAL CA  CB   sing N N 448 
VAL CA  HA   sing N N 449 
VAL C   O    doub N N 450 
VAL C   OXT  sing N N 451 
VAL CB  CG1  sing N N 452 
VAL CB  CG2  sing N N 453 
VAL CB  HB   sing N N 454 
VAL CG1 HG11 sing N N 455 
VAL CG1 HG12 sing N N 456 
VAL CG1 HG13 sing N N 457 
VAL CG2 HG21 sing N N 458 
VAL CG2 HG22 sing N N 459 
VAL CG2 HG23 sing N N 460 
VAL OXT HXT  sing N N 461 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'P01 AI057788' 1 
'Robert A. Welch Foundation'                                                                      'United States' Q-1279         2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6nir 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9DA0 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010741 
_atom_sites.fract_transf_matrix[1][2]   0.006201 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012403 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.022391 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 8.95735 ?       ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . ALA A 1 1   ? 19.00893 12.85141 -3.61591  1.000 76.70983  ? 1   ALA A N    1 
ATOM   2    C CA   . ALA A 1 1   ? 19.08411 12.84014 -2.12454  1.000 83.04286  ? 1   ALA A CA   1 
ATOM   3    C C    . ALA A 1 1   ? 17.71788 13.13160 -1.50063  1.000 80.21442  ? 1   ALA A C    1 
ATOM   4    O O    . ALA A 1 1   ? 16.84260 13.69878 -2.15498  1.000 83.64463  ? 1   ALA A O    1 
ATOM   5    C CB   . ALA A 1 1   ? 20.11326 13.85127 -1.64629  1.000 68.23851  ? 1   ALA A CB   1 
ATOM   6    H H1   . ALA A 1 1   ? 19.01305 12.01479 -3.91947  1.000 92.05180  ? 1   ALA A H1   1 
ATOM   7    H H2   . ALA A 1 1   ? 18.25889 13.25628 -3.87208  1.000 92.05180  ? 1   ALA A H2   1 
ATOM   8    H H3   . ALA A 1 1   ? 19.71005 13.28987 -3.94497  1.000 92.05180  ? 1   ALA A H3   1 
ATOM   9    H HA   . ALA A 1 1   ? 19.36284 11.95935 -1.82889  1.000 99.65143  ? 1   ALA A HA   1 
ATOM   10   H HB1  . ALA A 1 1   ? 20.15027 13.82997 -0.67723  1.000 81.88621  ? 1   ALA A HB1  1 
ATOM   11   H HB2  . ALA A 1 1   ? 20.97959 13.61888 -2.01558  1.000 81.88621  ? 1   ALA A HB2  1 
ATOM   12   H HB3  . ALA A 1 1   ? 19.85141 14.73520 -1.94796  1.000 81.88621  ? 1   ALA A HB3  1 
ATOM   13   N N    . PRO A 1 2   ? 17.53065 12.73855 -0.24231  1.000 82.43245  ? 2   PRO A N    1 
ATOM   14   C CA   . PRO A 1 2   ? 16.22990 12.94342 0.41606   1.000 73.85320  ? 2   PRO A CA   1 
ATOM   15   C C    . PRO A 1 2   ? 15.98403 14.41238 0.70807   1.000 73.72252  ? 2   PRO A C    1 
ATOM   16   O O    . PRO A 1 2   ? 16.93265 15.20776 0.78587   1.000 67.49289  ? 2   PRO A O    1 
ATOM   17   C CB   . PRO A 1 2   ? 16.35270 12.13171 1.71701   1.000 73.33049  ? 2   PRO A CB   1 
ATOM   18   C CG   . PRO A 1 2   ? 17.50785 11.20778 1.50337   1.000 82.09909  ? 2   PRO A CG   1 
ATOM   19   C CD   . PRO A 1 2   ? 18.44615 11.93722 0.59001   1.000 79.00269  ? 2   PRO A CD   1 
ATOM   20   H HA   . PRO A 1 2   ? 15.50977 12.59003 -0.12931  1.000 88.62384  ? 2   PRO A HA   1 
ATOM   21   H HB2  . PRO A 1 2   ? 16.52174 12.72944 2.46203   1.000 87.99659  ? 2   PRO A HB2  1 
ATOM   22   H HB3  . PRO A 1 2   ? 15.53523 11.63274 1.87088   1.000 87.99659  ? 2   PRO A HB3  1 
ATOM   23   H HG2  . PRO A 1 2   ? 17.93479 11.01478 2.35271   1.000 98.51891  ? 2   PRO A HG2  1 
ATOM   24   H HG3  . PRO A 1 2   ? 17.19823 10.38512 1.09318   1.000 98.51891  ? 2   PRO A HG3  1 
ATOM   25   H HD2  . PRO A 1 2   ? 19.04758 12.50797 1.09342   1.000 94.80322  ? 2   PRO A HD2  1 
ATOM   26   H HD3  . PRO A 1 2   ? 18.95558 11.31572 0.04676   1.000 94.80322  ? 2   PRO A HD3  1 
ATOM   27   N N    . PRO A 1 3   ? 14.72023 14.81261 0.88224   1.000 66.03386  ? 3   PRO A N    1 
ATOM   28   C CA   . PRO A 1 3   ? 14.44539 16.22738 1.18632   1.000 59.19740  ? 3   PRO A CA   1 
ATOM   29   C C    . PRO A 1 3   ? 15.05262 16.69966 2.49634   1.000 62.12777  ? 3   PRO A C    1 
ATOM   30   O O    . PRO A 1 3   ? 15.46325 17.86384 2.59014   1.000 51.42053  ? 3   PRO A O    1 
ATOM   31   C CB   . PRO A 1 3   ? 12.90972 16.28867 1.22531   1.000 64.20889  ? 3   PRO A CB   1 
ATOM   32   C CG   . PRO A 1 3   ? 12.45331 15.10664 0.43019   1.000 67.81444  ? 3   PRO A CG   1 
ATOM   33   C CD   . PRO A 1 3   ? 13.48169 14.03895 0.67800   1.000 70.84082  ? 3   PRO A CD   1 
ATOM   34   H HA   . PRO A 1 3   ? 14.77313 16.78445 0.46302   1.000 71.03688  ? 3   PRO A HA   1 
ATOM   35   H HB2  . PRO A 1 3   ? 12.60040 16.22997 2.14280   1.000 77.05067  ? 3   PRO A HB2  1 
ATOM   36   H HB3  . PRO A 1 3   ? 12.60229 17.11646 0.82388   1.000 77.05067  ? 3   PRO A HB3  1 
ATOM   37   H HG2  . PRO A 1 3   ? 11.57849 14.82140 0.73714   1.000 81.37733  ? 3   PRO A HG2  1 
ATOM   38   H HG3  . PRO A 1 3   ? 12.41550 15.33787 -0.51109  1.000 81.37733  ? 3   PRO A HG3  1 
ATOM   39   H HD2  . PRO A 1 3   ? 13.26132 13.52273 1.46911   1.000 85.00899  ? 3   PRO A HD2  1 
ATOM   40   H HD3  . PRO A 1 3   ? 13.56288 13.45142 -0.08954  1.000 85.00899  ? 3   PRO A HD3  1 
ATOM   41   N N    . SER A 1 4   ? 15.11791 15.83724 3.51526   1.000 71.10284  ? 4   SER A N    1 
ATOM   42   C CA   . SER A 1 4   ? 15.68766 16.25046 4.79315   1.000 66.92764  ? 4   SER A CA   1 
ATOM   43   C C    . SER A 1 4   ? 17.09168 16.81516 4.62456   1.000 56.39461  ? 4   SER A C    1 
ATOM   44   O O    . SER A 1 4   ? 17.48335 17.73310 5.35506   1.000 58.58606  ? 4   SER A O    1 
ATOM   45   C CB   . SER A 1 4   ? 15.71094 15.06512 5.76275   1.000 73.00881  ? 4   SER A CB   1 
ATOM   46   O OG   . SER A 1 4   ? 16.53841 14.02476 5.27239   1.000 72.21209  ? 4   SER A OG   1 
ATOM   47   H H    . SER A 1 4   ? 14.84355 15.02256 3.49036   1.000 85.32340  ? 4   SER A H    1 
ATOM   48   H HA   . SER A 1 4   ? 15.12760 16.94368 5.17614   1.000 80.31317  ? 4   SER A HA   1 
ATOM   49   H HB2  . SER A 1 4   ? 16.05517 15.36476 6.61868   1.000 87.61057  ? 4   SER A HB2  1 
ATOM   50   H HB3  . SER A 1 4   ? 14.80811 14.72653 5.86839   1.000 87.61057  ? 4   SER A HB3  1 
ATOM   51   H HG   . SER A 1 4   ? 16.50892 13.36524 5.79178   1.000 86.65451  ? 4   SER A HG   1 
ATOM   52   N N    . ILE A 1 5   ? 17.85807 16.29063 3.67009   1.000 58.68392  ? 5   ILE A N    1 
ATOM   53   C CA   . ILE A 1 5   ? 19.22157 16.76882 3.47257   1.000 48.42027  ? 5   ILE A CA   1 
ATOM   54   C C    . ILE A 1 5   ? 19.22518 18.07778 2.69406   1.000 43.69694  ? 5   ILE A C    1 
ATOM   55   O O    . ILE A 1 5   ? 19.96881 19.00653 3.02902   1.000 45.59414  ? 5   ILE A O    1 
ATOM   56   C CB   . ILE A 1 5   ? 20.06831 15.68888 2.77328   1.000 45.62195  ? 5   ILE A CB   1 
ATOM   57   C CG1  . ILE A 1 5   ? 20.10585 14.41644 3.62289   1.000 50.11515  ? 5   ILE A CG1  1 
ATOM   58   C CG2  . ILE A 1 5   ? 21.48344 16.19796 2.51657   1.000 46.13253  ? 5   ILE A CG2  1 
ATOM   59   C CD1  . ILE A 1 5   ? 20.92901 13.29994 3.02185   1.000 62.84901  ? 5   ILE A CD1  1 
ATOM   60   H H    . ILE A 1 5   ? 17.61529 15.66575 3.13141   1.000 70.42071  ? 5   ILE A H    1 
ATOM   61   H HA   . ILE A 1 5   ? 19.61636 16.93949 4.34201   1.000 58.10432  ? 5   ILE A HA   1 
ATOM   62   H HB   . ILE A 1 5   ? 19.65664 15.48330 1.91937   1.000 54.74634  ? 5   ILE A HB   1 
ATOM   63   H HG12 . ILE A 1 5   ? 20.48761 14.63151 4.48828   1.000 60.13818  ? 5   ILE A HG12 1 
ATOM   64   H HG13 . ILE A 1 5   ? 19.19946 14.08875 3.73231   1.000 60.13818  ? 5   ILE A HG13 1 
ATOM   65   H HG21 . ILE A 1 5   ? 22.00284 15.49145 2.10188   1.000 55.35904  ? 5   ILE A HG21 1 
ATOM   66   H HG22 . ILE A 1 5   ? 21.44034 16.96670 1.92660   1.000 55.35904  ? 5   ILE A HG22 1 
ATOM   67   H HG23 . ILE A 1 5   ? 21.88591 16.45184 3.36183   1.000 55.35904  ? 5   ILE A HG23 1 
ATOM   68   H HD11 . ILE A 1 5   ? 20.57863 12.44897 3.32842   1.000 75.41881  ? 5   ILE A HD11 1 
ATOM   69   H HD12 . ILE A 1 5   ? 20.87306 13.35165 2.05485   1.000 75.41881  ? 5   ILE A HD12 1 
ATOM   70   H HD13 . ILE A 1 5   ? 21.85122 13.39950 3.30562   1.000 75.41881  ? 5   ILE A HD13 1 
ATOM   71   N N    . TRP A 1 6   ? 18.40334 18.17469 1.64360   1.000 48.95440  ? 6   TRP A N    1 
ATOM   72   C CA   . TRP A 1 6   ? 18.34789 19.40721 0.86528   1.000 49.49698  ? 6   TRP A CA   1 
ATOM   73   C C    . TRP A 1 6   ? 17.95028 20.59580 1.73264   1.000 43.20473  ? 6   TRP A C    1 
ATOM   74   O O    . TRP A 1 6   ? 18.42210 21.71705 1.50552   1.000 44.17307  ? 6   TRP A O    1 
ATOM   75   C CB   . TRP A 1 6   ? 17.36453 19.25165 -0.29978  1.000 46.62450  ? 6   TRP A CB   1 
ATOM   76   C CG   . TRP A 1 6   ? 17.91460 18.53694 -1.51736  1.000 49.67717  ? 6   TRP A CG   1 
ATOM   77   C CD1  . TRP A 1 6   ? 17.61865 17.26785 -1.92899  1.000 51.48903  ? 6   TRP A CD1  1 
ATOM   78   C CD2  . TRP A 1 6   ? 18.83826 19.06340 -2.48188  1.000 47.20638  ? 6   TRP A CD2  1 
ATOM   79   N NE1  . TRP A 1 6   ? 18.30188 16.97171 -3.08454  1.000 52.38060  ? 6   TRP A NE1  1 
ATOM   80   C CE2  . TRP A 1 6   ? 19.05848 18.05556 -3.44408  1.000 49.47847  ? 6   TRP A CE2  1 
ATOM   81   C CE3  . TRP A 1 6   ? 19.50250 20.28621 -2.62290  1.000 47.52589  ? 6   TRP A CE3  1 
ATOM   82   C CZ2  . TRP A 1 6   ? 19.91388 18.23388 -4.53146  1.000 49.63821  ? 6   TRP A CZ2  1 
ATOM   83   C CZ3  . TRP A 1 6   ? 20.35361 20.46005 -3.70298  1.000 46.19583  ? 6   TRP A CZ3  1 
ATOM   84   C CH2  . TRP A 1 6   ? 20.55060 19.43940 -4.64224  1.000 50.26479  ? 6   TRP A CH2  1 
ATOM   85   H H    . TRP A 1 6   ? 17.87862 17.55141 1.36830   1.000 58.74528  ? 6   TRP A H    1 
ATOM   86   H HA   . TRP A 1 6   ? 19.22723 19.58200 0.49498   1.000 59.39638  ? 6   TRP A HA   1 
ATOM   87   H HB2  . TRP A 1 6   ? 16.59808 18.74532 0.01181   1.000 55.94941  ? 6   TRP A HB2  1 
ATOM   88   H HB3  . TRP A 1 6   ? 17.08465 20.13567 -0.58451  1.000 55.94941  ? 6   TRP A HB3  1 
ATOM   89   H HD1  . TRP A 1 6   ? 17.03858 16.68805 -1.49052  1.000 61.78683  ? 6   TRP A HD1  1 
ATOM   90   H HE1  . TRP A 1 6   ? 18.26095 16.22679 -3.51234  1.000 62.85672  ? 6   TRP A HE1  1 
ATOM   91   H HE3  . TRP A 1 6   ? 19.37563 20.96898 -2.00432  1.000 57.03107  ? 6   TRP A HE3  1 
ATOM   92   H HZ2  . TRP A 1 6   ? 20.04622 17.55880 -5.15727  1.000 59.56585  ? 6   TRP A HZ2  1 
ATOM   93   H HZ3  . TRP A 1 6   ? 20.80177 21.26841 -3.80598  1.000 55.43499  ? 6   TRP A HZ3  1 
ATOM   94   H HH2  . TRP A 1 6   ? 21.12729 19.58480 -5.35720  1.000 60.31775  ? 6   TRP A HH2  1 
ATOM   95   N N    . SER A 1 7   ? 17.09736 20.37136 2.73284   1.000 46.52977  ? 7   SER A N    1 
ATOM   96   C CA   . SER A 1 7   ? 16.64997 21.46410 3.58607   1.000 51.48285  ? 7   SER A CA   1 
ATOM   97   C C    . SER A 1 7   ? 17.77383 22.01240 4.45458   1.000 44.13615  ? 7   SER A C    1 
ATOM   98   O O    . SER A 1 7   ? 17.64632 23.12341 4.98035   1.000 42.51713  ? 7   SER A O    1 
ATOM   99   C CB   . SER A 1 7   ? 15.48785 21.00419 4.46923   1.000 50.39505  ? 7   SER A CB   1 
ATOM   100  O OG   . SER A 1 7   ? 15.95051 20.45153 5.68926   1.000 49.53018  ? 7   SER A OG   1 
ATOM   101  H H    . SER A 1 7   ? 16.76783 19.60295 2.93421   1.000 55.83572  ? 7   SER A H    1 
ATOM   102  H HA   . SER A 1 7   ? 16.32749 22.18470 3.02248   1.000 61.77942  ? 7   SER A HA   1 
ATOM   103  H HB2  . SER A 1 7   ? 14.92252 21.76756 4.66561   1.000 60.47406  ? 7   SER A HB2  1 
ATOM   104  H HB3  . SER A 1 7   ? 14.98003 20.32925 3.99228   1.000 60.47406  ? 7   SER A HB3  1 
ATOM   105  H HG   . SER A 1 7   ? 15.30826 20.35208 6.22145   1.000 59.43621  ? 7   SER A HG   1 
ATOM   106  N N    . ARG A 1 8   ? 18.86548 21.25923 4.61802   1.000 47.99590  ? 8   ARG A N    1 
ATOM   107  C CA   . ARG A 1 8   ? 20.01659 21.75777 5.35960   1.000 41.17216  ? 8   ARG A CA   1 
ATOM   108  C C    . ARG A 1 8   ? 20.81775 22.78232 4.56611   1.000 40.65701  ? 8   ARG A C    1 
ATOM   109  O O    . ARG A 1 8   ? 21.58839 23.54370 5.16025   1.000 36.93615  ? 8   ARG A O    1 
ATOM   110  C CB   . ARG A 1 8   ? 20.93695 20.60057 5.74948   1.000 44.41583  ? 8   ARG A CB   1 
ATOM   111  C CG   . ARG A 1 8   ? 20.28955 19.51410 6.59106   1.000 42.74620  ? 8   ARG A CG   1 
ATOM   112  C CD   . ARG A 1 8   ? 21.11300 18.23692 6.50474   1.000 45.55575  ? 8   ARG A CD   1 
ATOM   113  N NE   . ARG A 1 8   ? 20.58239 17.16745 7.33909   1.000 44.93673  ? 8   ARG A NE   1 
ATOM   114  C CZ   . ARG A 1 8   ? 20.90588 16.97830 8.61109   1.000 43.88545  ? 8   ARG A CZ   1 
ATOM   115  N NH1  . ARG A 1 8   ? 21.74090 17.78877 9.24102   1.000 41.65682  ? 8   ARG A NH1  1 
ATOM   116  N NH2  . ARG A 1 8   ? 20.37960 15.94880 9.26663   1.000 46.86572  ? 8   ARG A NH2  1 
ATOM   117  H H    . ARG A 1 8   ? 18.96060 20.46191 4.31007   1.000 57.59509  ? 8   ARG A H    1 
ATOM   118  H HA   . ARG A 1 8   ? 19.69362 22.18064 6.17064   1.000 49.40659  ? 8   ARG A HA   1 
ATOM   119  H HB2  . ARG A 1 8   ? 21.26364 20.18233 4.93755   1.000 53.29899  ? 8   ARG A HB2  1 
ATOM   120  H HB3  . ARG A 1 8   ? 21.67975 20.95886 6.26014   1.000 53.29899  ? 8   ARG A HB3  1 
ATOM   121  H HG2  . ARG A 1 8   ? 20.24932 19.79750 7.51787   1.000 51.29544  ? 8   ARG A HG2  1 
ATOM   122  H HG3  . ARG A 1 8   ? 19.39587 19.33222 6.26067   1.000 51.29544  ? 8   ARG A HG3  1 
ATOM   123  H HD2  . ARG A 1 8   ? 21.11871 17.92569 5.58604   1.000 54.66690  ? 8   ARG A HD2  1 
ATOM   124  H HD3  . ARG A 1 8   ? 22.01871 18.42409 6.79725   1.000 54.66690  ? 8   ARG A HD3  1 
ATOM   125  H HE   . ARG A 1 8   ? 20.02134 16.62174 6.98268   1.000 53.92407  ? 8   ARG A HE   1 
ATOM   126  H HH11 . ARG A 1 8   ? 21.93689 17.64740 10.06637  1.000 49.98819  ? 8   ARG A HH11 1 
ATOM   127  H HH12 . ARG A 1 8   ? 22.08761 18.45689 8.82508   1.000 49.98819  ? 8   ARG A HH12 1 
ATOM   128  H HH21 . ARG A 1 8   ? 19.83687 15.41571 8.86555   1.000 56.23886  ? 8   ARG A HH21 1 
ATOM   129  H HH22 . ARG A 1 8   ? 20.58180 15.81576 10.09187  1.000 56.23886  ? 8   ARG A HH22 1 
ATOM   130  N N    . ILE A 1 9   ? 20.67276 22.80717 3.24474   1.000 39.63186  ? 9   ILE A N    1 
ATOM   131  C CA   . ILE A 1 9   ? 21.40541 23.74456 2.40103   1.000 39.81111  ? 9   ILE A CA   1 
ATOM   132  C C    . ILE A 1 9   ? 20.62591 25.05209 2.36649   1.000 42.08111  ? 9   ILE A C    1 
ATOM   133  O O    . ILE A 1 9   ? 19.46106 25.07893 1.95448   1.000 44.15140  ? 9   ILE A O    1 
ATOM   134  C CB   . ILE A 1 9   ? 21.60271 23.19002 0.98310   1.000 37.55177  ? 9   ILE A CB   1 
ATOM   135  C CG1  . ILE A 1 9   ? 22.34115 21.85250 1.00919   1.000 37.34990  ? 9   ILE A CG1  1 
ATOM   136  C CG2  . ILE A 1 9   ? 22.37927 24.18988 0.13042   1.000 42.55791  ? 9   ILE A CG2  1 
ATOM   137  C CD1  . ILE A 1 9   ? 22.16120 21.04674 -0.26585  1.000 35.37231  ? 9   ILE A CD1  1 
ATOM   138  H H    . ILE A 1 9   ? 20.14866 22.28365 2.80788   1.000 47.55824  ? 9   ILE A H    1 
ATOM   139  H HA   . ILE A 1 9   ? 22.28014 23.90767 2.78721   1.000 47.77333  ? 9   ILE A HA   1 
ATOM   140  H HB   . ILE A 1 9   ? 20.72411 23.04685 0.59777   1.000 45.06213  ? 9   ILE A HB   1 
ATOM   141  H HG12 . ILE A 1 9   ? 23.28955 22.01929 1.12583   1.000 44.81988  ? 9   ILE A HG12 1 
ATOM   142  H HG13 . ILE A 1 9   ? 22.00429 21.32184 1.74798   1.000 44.81988  ? 9   ILE A HG13 1 
ATOM   143  H HG21 . ILE A 1 9   ? 23.15693 24.49068 0.62607   1.000 51.06949  ? 9   ILE A HG21 1 
ATOM   144  H HG22 . ILE A 1 9   ? 22.65814 23.75518 -0.69065  1.000 51.06949  ? 9   ILE A HG22 1 
ATOM   145  H HG23 . ILE A 1 9   ? 21.80474 24.94439 -0.07339  1.000 51.06949  ? 9   ILE A HG23 1 
ATOM   146  H HD11 . ILE A 1 9   ? 22.52655 21.54891 -1.01099  1.000 42.44677  ? 9   ILE A HD11 1 
ATOM   147  H HD12 . ILE A 1 9   ? 22.62977 20.20234 -0.17458  1.000 42.44677  ? 9   ILE A HD12 1 
ATOM   148  H HD13 . ILE A 1 9   ? 21.21505 20.88640 -0.40722  1.000 42.44677  ? 9   ILE A HD13 1 
ATOM   149  N N    . VAL A 1 10  ? 21.26360 26.13549 2.80029   1.000 38.29877  ? 10  VAL A N    1 
ATOM   150  C CA   . VAL A 1 10  ? 20.64787 27.45444 2.80203   1.000 45.23865  ? 10  VAL A CA   1 
ATOM   151  C C    . VAL A 1 10  ? 21.60683 28.44131 2.15418   1.000 40.54301  ? 10  VAL A C    1 
ATOM   152  O O    . VAL A 1 10  ? 22.82936 28.27077 2.19869   1.000 34.21167  ? 10  VAL A O    1 
ATOM   153  C CB   . VAL A 1 10  ? 20.28044 27.91817 4.23031   1.000 44.81346  ? 10  VAL A CB   1 
ATOM   154  C CG1  . VAL A 1 10  ? 19.47173 26.84361 4.94157   1.000 49.51201  ? 10  VAL A CG1  1 
ATOM   155  C CG2  . VAL A 1 10  ? 21.53551 28.27656 5.01826   1.000 44.74388  ? 10  VAL A CG2  1 
ATOM   156  H H    . VAL A 1 10  ? 22.06835 26.12952 3.10352   1.000 45.95853  ? 10  VAL A H    1 
ATOM   157  H HA   . VAL A 1 10  ? 19.83493 27.42526 2.27365   1.000 54.28638  ? 10  VAL A HA   1 
ATOM   158  H HB   . VAL A 1 10  ? 19.73232 28.71650 4.17441   1.000 53.77616  ? 10  VAL A HB   1 
ATOM   159  H HG11 . VAL A 1 10  ? 19.13409 26.21542 4.28409   1.000 59.41441  ? 10  VAL A HG11 1 
ATOM   160  H HG12 . VAL A 1 10  ? 20.04524 26.38376 5.57443   1.000 59.41441  ? 10  VAL A HG12 1 
ATOM   161  H HG13 . VAL A 1 10  ? 18.73224 27.26250 5.40910   1.000 59.41441  ? 10  VAL A HG13 1 
ATOM   162  H HG21 . VAL A 1 10  ? 21.32497 28.27548 5.96514   1.000 53.69266  ? 10  VAL A HG21 1 
ATOM   163  H HG22 . VAL A 1 10  ? 22.22396 27.61918 4.83173   1.000 53.69266  ? 10  VAL A HG22 1 
ATOM   164  H HG23 . VAL A 1 10  ? 21.83748 29.15771 4.74755   1.000 53.69266  ? 10  VAL A HG23 1 
ATOM   165  N N    . ASN A 1 11  ? 21.04227 29.48083 1.54491   1.000 39.38141  ? 11  ASN A N    1 
ATOM   166  C CA   . ASN A 1 11  ? 21.86598 30.54172 0.98367   1.000 39.88008  ? 11  ASN A CA   1 
ATOM   167  C C    . ASN A 1 11  ? 22.64995 31.22290 2.09797   1.000 41.70161  ? 11  ASN A C    1 
ATOM   168  O O    . ASN A 1 11  ? 22.12482 31.47946 3.18506   1.000 39.72352  ? 11  ASN A O    1 
ATOM   169  C CB   . ASN A 1 11  ? 21.00037 31.55750 0.23770   1.000 44.20573  ? 11  ASN A CB   1 
ATOM   170  C CG   . ASN A 1 11  ? 20.13035 32.37683 1.16608   1.000 57.32232  ? 11  ASN A CG   1 
ATOM   171  O OD1  . ASN A 1 11  ? 20.47422 33.50539 1.52043   1.000 60.07894  ? 11  ASN A OD1  1 
ATOM   172  N ND2  . ASN A 1 11  ? 18.99572 31.81532 1.56564   1.000 61.06493  ? 11  ASN A ND2  1 
ATOM   173  H H    . ASN A 1 11  ? 20.19542 29.59274 1.44531   1.000 47.25769  ? 11  ASN A H    1 
ATOM   174  H HA   . ASN A 1 11  ? 22.49191 30.16946 0.34295   1.000 47.85610  ? 11  ASN A HA   1 
ATOM   175  H HB2  . ASN A 1 11  ? 21.57668 32.16698 -0.24944  1.000 53.04687  ? 11  ASN A HB2  1 
ATOM   176  H HB3  . ASN A 1 11  ? 20.41956 31.08550 -0.37937  1.000 53.04687  ? 11  ASN A HB3  1 
ATOM   177  H HD21 . ASN A 1 11  ? 18.78876 31.02524 1.29630   1.000 73.27792  ? 11  ASN A HD21 1 
ATOM   178  H HD22 . ASN A 1 11  ? 18.46763 32.24164 2.09382   1.000 73.27792  ? 11  ASN A HD22 1 
ATOM   179  N N    . PHE A 1 12  ? 23.92099 31.50546 1.82602   1.000 40.65353  ? 12  PHE A N    1 
ATOM   180  C CA   . PHE A 1 12  ? 24.80954 32.07702 2.83512   1.000 39.48445  ? 12  PHE A CA   1 
ATOM   181  C C    . PHE A 1 12  ? 25.80323 32.97598 2.11375   1.000 35.29730  ? 12  PHE A C    1 
ATOM   182  O O    . PHE A 1 12  ? 26.68384 32.48474 1.40041   1.000 34.74697  ? 12  PHE A O    1 
ATOM   183  C CB   . PHE A 1 12  ? 25.51516 30.97446 3.62455   1.000 33.75394  ? 12  PHE A CB   1 
ATOM   184  C CG   . PHE A 1 12  ? 26.17781 31.45695 4.88475   1.000 38.48824  ? 12  PHE A CG   1 
ATOM   185  C CD1  . PHE A 1 12  ? 25.42094 31.89922 5.95855   1.000 38.72644  ? 12  PHE A CD1  1 
ATOM   186  C CD2  . PHE A 1 12  ? 27.55799 31.45952 4.99874   1.000 36.16208  ? 12  PHE A CD2  1 
ATOM   187  C CE1  . PHE A 1 12  ? 26.02980 32.34355 7.11855   1.000 36.98620  ? 12  PHE A CE1  1 
ATOM   188  C CE2  . PHE A 1 12  ? 28.17182 31.90072 6.15609   1.000 41.48913  ? 12  PHE A CE2  1 
ATOM   189  C CZ   . PHE A 1 12  ? 27.40699 32.34347 7.21715   1.000 39.21095  ? 12  PHE A CZ   1 
ATOM   190  H H    . PHE A 1 12  ? 24.29448 31.37523 1.06238   1.000 48.78424  ? 12  PHE A H    1 
ATOM   191  H HA   . PHE A 1 12  ? 24.30280 32.61990 3.45913   1.000 47.38134  ? 12  PHE A HA   1 
ATOM   192  H HB2  . PHE A 1 12  ? 24.86144 30.30233 3.87312   1.000 40.50472  ? 12  PHE A HB2  1 
ATOM   193  H HB3  . PHE A 1 12  ? 26.20032 30.57921 3.06309   1.000 40.50472  ? 12  PHE A HB3  1 
ATOM   194  H HD1  . PHE A 1 12  ? 24.49289 31.89721 5.89843   1.000 46.47173  ? 12  PHE A HD1  1 
ATOM   195  H HD2  . PHE A 1 12  ? 28.07817 31.16080 4.28805   1.000 43.39450  ? 12  PHE A HD2  1 
ATOM   196  H HE1  . PHE A 1 12  ? 25.51207 32.64197 7.83116   1.000 44.38344  ? 12  PHE A HE1  1 
ATOM   197  H HE2  . PHE A 1 12  ? 29.09962 31.89935 6.22010   1.000 49.78695  ? 12  PHE A HE2  1 
ATOM   198  H HZ   . PHE A 1 12  ? 27.81852 32.64090 7.99630   1.000 47.05314  ? 12  PHE A HZ   1 
ATOM   199  N N    . GLY A 1 13  ? 25.65060 34.28545 2.28477   1.000 37.38134  ? 13  GLY A N    1 
ATOM   200  C CA   . GLY A 1 13  ? 26.53576 35.21711 1.60402   1.000 32.84644  ? 13  GLY A CA   1 
ATOM   201  C C    . GLY A 1 13  ? 26.44782 35.05632 0.09875   1.000 34.42119  ? 13  GLY A C    1 
ATOM   202  O O    . GLY A 1 13  ? 25.35887 35.02848 -0.48485  1.000 41.83286  ? 13  GLY A O    1 
ATOM   203  H H    . GLY A 1 13  ? 25.05237 34.65322 2.78123   1.000 44.85761  ? 13  GLY A H    1 
ATOM   204  H HA2  . GLY A 1 13  ? 26.29055 36.12704 1.83379   1.000 39.41573  ? 13  GLY A HA2  1 
ATOM   205  H HA3  . GLY A 1 13  ? 27.45184 35.05759 1.88017   1.000 39.41573  ? 13  GLY A HA3  1 
ATOM   206  N N    . SER A 1 14  ? 27.60865 34.94915 -0.54642  1.000 42.08167  ? 14  SER A N    1 
ATOM   207  C CA   . SER A 1 14  ? 27.69549 34.78961 -1.99214  1.000 42.58224  ? 14  SER A CA   1 
ATOM   208  C C    . SER A 1 14  ? 27.58749 33.33501 -2.42930  1.000 41.60079  ? 14  SER A C    1 
ATOM   209  O O    . SER A 1 14  ? 27.82535 33.03078 -3.60360  1.000 38.14159  ? 14  SER A O    1 
ATOM   210  C CB   . SER A 1 14  ? 29.01184 35.37804 -2.50589  1.000 46.49883  ? 14  SER A CB   1 
ATOM   211  O OG   . SER A 1 14  ? 30.11853 34.71781 -1.91422  1.000 45.90196  ? 14  SER A OG   1 
ATOM   212  H H    . SER A 1 14  ? 28.37545 34.96675 -0.15743  1.000 50.49801  ? 14  SER A H    1 
ATOM   213  H HA   . SER A 1 14  ? 26.96464 35.28097 -2.39874  1.000 51.09868  ? 14  SER A HA   1 
ATOM   214  H HB2  . SER A 1 14  ? 29.05422 35.26650 -3.46852  1.000 55.79860  ? 14  SER A HB2  1 
ATOM   215  H HB3  . SER A 1 14  ? 29.04721 36.32052 -2.27924  1.000 55.79860  ? 14  SER A HB3  1 
ATOM   216  H HG   . SER A 1 14  ? 30.83478 35.08220 -2.15877  1.000 55.08235  ? 14  SER A HG   1 
ATOM   217  N N    . GLY A 1 15  ? 27.25085 32.43477 -1.51188  1.000 37.92604  ? 15  GLY A N    1 
ATOM   218  C CA   . GLY A 1 15  ? 27.14408 31.02816 -1.82984  1.000 39.02786  ? 15  GLY A CA   1 
ATOM   219  C C    . GLY A 1 15  ? 26.12305 30.32027 -0.96488  1.000 37.78555  ? 15  GLY A C    1 
ATOM   220  O O    . GLY A 1 15  ? 24.98389 30.77936 -0.83784  1.000 39.47150  ? 15  GLY A O    1 
ATOM   221  H H    . GLY A 1 15  ? 27.07838 32.62102 -0.69020  1.000 45.51125  ? 15  GLY A H    1 
ATOM   222  H HA2  . GLY A 1 15  ? 26.88155 30.92763 -2.75821  1.000 46.83343  ? 15  GLY A HA2  1 
ATOM   223  H HA3  . GLY A 1 15  ? 28.00559 30.60252 -1.69741  1.000 46.83343  ? 15  GLY A HA3  1 
ATOM   224  N N    . TRP A 1 16  ? 26.51956 29.20799 -0.35430  1.000 32.31803  ? 16  TRP A N    1 
ATOM   225  C CA   . TRP A 1 16  ? 25.59015 28.35011 0.36025   1.000 33.17705  ? 16  TRP A CA   1 
ATOM   226  C C    . TRP A 1 16  ? 26.28109 27.77921 1.58743   1.000 33.24472  ? 16  TRP A C    1 
ATOM   227  O O    . TRP A 1 16  ? 27.50382 27.83753 1.71853   1.000 33.65759  ? 16  TRP A O    1 
ATOM   228  C CB   . TRP A 1 16  ? 25.07929 27.22448 -0.55024  1.000 32.88219  ? 16  TRP A CB   1 
ATOM   229  C CG   . TRP A 1 16  ? 24.42655 27.75661 -1.78340  1.000 33.32148  ? 16  TRP A CG   1 
ATOM   230  C CD1  . TRP A 1 16  ? 25.04288 28.15541 -2.93395  1.000 37.19206  ? 16  TRP A CD1  1 
ATOM   231  C CD2  . TRP A 1 16  ? 23.02708 27.96941 -1.98402  1.000 39.88900  ? 16  TRP A CD2  1 
ATOM   232  N NE1  . TRP A 1 16  ? 24.11172 28.60159 -3.84001  1.000 38.30623  ? 16  TRP A NE1  1 
ATOM   233  C CE2  . TRP A 1 16  ? 22.86540 28.49534 -3.28081  1.000 41.05978  ? 16  TRP A CE2  1 
ATOM   234  C CE3  . TRP A 1 16  ? 21.89371 27.76331 -1.19373  1.000 41.27555  ? 16  TRP A CE3  1 
ATOM   235  C CZ2  . TRP A 1 16  ? 21.61607 28.81712 -3.80475  1.000 38.37660  ? 16  TRP A CZ2  1 
ATOM   236  C CZ3  . TRP A 1 16  ? 20.65379 28.08186 -1.71631  1.000 39.08739  ? 16  TRP A CZ3  1 
ATOM   237  C CH2  . TRP A 1 16  ? 20.52504 28.60297 -3.00807  1.000 38.92676  ? 16  TRP A CH2  1 
ATOM   238  H H    . TRP A 1 16  ? 27.33261 28.92802 -0.34128  1.000 38.78164  ? 16  TRP A H    1 
ATOM   239  H HA   . TRP A 1 16  ? 24.82800 28.86537 0.66770   1.000 39.81246  ? 16  TRP A HA   1 
ATOM   240  H HB2  . TRP A 1 16  ? 25.82667 26.66742 -0.81857  1.000 39.45862  ? 16  TRP A HB2  1 
ATOM   241  H HB3  . TRP A 1 16  ? 24.42713 26.69407 -0.06625  1.000 39.45862  ? 16  TRP A HB3  1 
ATOM   242  H HD1  . TRP A 1 16  ? 25.96048 28.12893 -3.08299  1.000 44.63048  ? 16  TRP A HD1  1 
ATOM   243  H HE1  . TRP A 1 16  ? 24.28292 28.89878 -4.62866  1.000 45.96747  ? 16  TRP A HE1  1 
ATOM   244  H HE3  . TRP A 1 16  ? 21.97159 27.41877 -0.33343  1.000 49.53067  ? 16  TRP A HE3  1 
ATOM   245  H HZ2  . TRP A 1 16  ? 21.52693 29.16413 -4.66297  1.000 46.05192  ? 16  TRP A HZ2  1 
ATOM   246  H HZ3  . TRP A 1 16  ? 19.89211 27.94731 -1.19994  1.000 46.90486  ? 16  TRP A HZ3  1 
ATOM   247  H HH2  . TRP A 1 16  ? 19.67813 28.80855 -3.33267  1.000 46.71211  ? 16  TRP A HH2  1 
ATOM   248  N N    . GLY A 1 17  ? 25.47588 27.23687 2.50154   1.000 34.25435  ? 17  GLY A N    1 
ATOM   249  C CA   . GLY A 1 17  ? 25.99694 26.56022 3.66392   1.000 29.86646  ? 17  GLY A CA   1 
ATOM   250  C C    . GLY A 1 17  ? 25.11074 25.37827 4.01646   1.000 34.50608  ? 17  GLY A C    1 
ATOM   251  O O    . GLY A 1 17  ? 23.99448 25.25280 3.51295   1.000 34.45410  ? 17  GLY A O    1 
ATOM   252  H H    . GLY A 1 17  ? 24.61694 27.25284 2.46195   1.000 41.10522  ? 17  GLY A H    1 
ATOM   253  H HA2  . GLY A 1 17  ? 26.89469 26.23929 3.48519   1.000 35.83975  ? 17  GLY A HA2  1 
ATOM   254  H HA3  . GLY A 1 17  ? 26.02386 27.17032 4.41754   1.000 35.83975  ? 17  GLY A HA3  1 
ATOM   255  N N    . PHE A 1 18  ? 25.62403 24.52842 4.89683   1.000 31.71944  ? 18  PHE A N    1 
ATOM   256  C CA   . PHE A 1 18  ? 25.02138 23.22907 5.16366   1.000 35.88409  ? 18  PHE A CA   1 
ATOM   257  C C    . PHE A 1 18  ? 24.94405 23.00361 6.66234   1.000 34.72861  ? 18  PHE A C    1 
ATOM   258  O O    . PHE A 1 18  ? 25.96624 23.05959 7.35331   1.000 31.44414  ? 18  PHE A O    1 
ATOM   259  C CB   . PHE A 1 18  ? 25.83238 22.11478 4.49674   1.000 34.80700  ? 18  PHE A CB   1 
ATOM   260  C CG   . PHE A 1 18  ? 25.22772 20.75553 4.64293   1.000 31.08513  ? 18  PHE A CG   1 
ATOM   261  C CD1  . PHE A 1 18  ? 24.09284 20.41366 3.93172   1.000 36.50461  ? 18  PHE A CD1  1 
ATOM   262  C CD2  . PHE A 1 18  ? 25.79373 19.81604 5.48516   1.000 34.28647  ? 18  PHE A CD2  1 
ATOM   263  C CE1  . PHE A 1 18  ? 23.53346 19.15996 4.05670   1.000 38.50688  ? 18  PHE A CE1  1 
ATOM   264  C CE2  . PHE A 1 18  ? 25.23547 18.55932 5.61589   1.000 35.50002  ? 18  PHE A CE2  1 
ATOM   265  C CZ   . PHE A 1 18  ? 24.10364 18.23263 4.90132   1.000 35.00140  ? 18  PHE A CZ   1 
ATOM   266  H H    . PHE A 1 18  ? 26.33212 24.68439 5.35930   1.000 38.06333  ? 18  PHE A H    1 
ATOM   267  H HA   . PHE A 1 18  ? 24.11583 23.21751 4.81616   1.000 43.06091  ? 18  PHE A HA   1 
ATOM   268  H HB2  . PHE A 1 18  ? 25.90340 22.30618 3.54846   1.000 41.76840  ? 18  PHE A HB2  1 
ATOM   269  H HB3  . PHE A 1 18  ? 26.71550 22.08998 4.89723   1.000 41.76840  ? 18  PHE A HB3  1 
ATOM   270  H HD1  . PHE A 1 18  ? 23.70216 21.03662 3.36234   1.000 43.80553  ? 18  PHE A HD1  1 
ATOM   271  H HD2  . PHE A 1 18  ? 26.55815 20.03257 5.96857   1.000 41.14376  ? 18  PHE A HD2  1 
ATOM   272  H HE1  . PHE A 1 18  ? 22.77142 18.94014 3.57103   1.000 46.20826  ? 18  PHE A HE1  1 
ATOM   273  H HE2  . PHE A 1 18  ? 25.62305 17.93459 6.18544   1.000 42.60002  ? 18  PHE A HE2  1 
ATOM   274  H HZ   . PHE A 1 18  ? 23.72518 17.38765 4.98895   1.000 42.00167  ? 18  PHE A HZ   1 
ATOM   275  N N    . TRP A 1 19  ? 23.73858 22.74397 7.16082   1.000 34.15254  ? 19  TRP A N    1 
ATOM   276  C CA   . TRP A 1 19  ? 23.53897 22.44724 8.57667   1.000 33.93553  ? 19  TRP A CA   1 
ATOM   277  C C    . TRP A 1 19  ? 23.91595 20.99027 8.81377   1.000 39.62830  ? 19  TRP A C    1 
ATOM   278  O O    . TRP A 1 19  ? 23.14836 20.07660 8.50113   1.000 42.41164  ? 19  TRP A O    1 
ATOM   279  C CB   . TRP A 1 19  ? 22.09917 22.72389 8.99295   1.000 35.16109  ? 19  TRP A CB   1 
ATOM   280  C CG   . TRP A 1 19  ? 21.77342 24.18331 9.12279   1.000 35.76326  ? 19  TRP A CG   1 
ATOM   281  C CD1  . TRP A 1 19  ? 21.05909 24.94405 8.24571   1.000 36.53169  ? 19  TRP A CD1  1 
ATOM   282  C CD2  . TRP A 1 19  ? 22.15430 25.05772 10.19342  1.000 36.85508  ? 19  TRP A CD2  1 
ATOM   283  N NE1  . TRP A 1 19  ? 20.96764 26.23607 8.70338   1.000 36.72903  ? 19  TRP A NE1  1 
ATOM   284  C CE2  . TRP A 1 19  ? 21.63393 26.33290 9.89602   1.000 31.37401  ? 19  TRP A CE2  1 
ATOM   285  C CE3  . TRP A 1 19  ? 22.88721 24.88657 11.37180  1.000 35.12301  ? 19  TRP A CE3  1 
ATOM   286  C CZ2  . TRP A 1 19  ? 21.82019 27.43052 10.73512  1.000 37.68292  ? 19  TRP A CZ2  1 
ATOM   287  C CZ3  . TRP A 1 19  ? 23.07146 25.97722 12.20399  1.000 40.56190  ? 19  TRP A CZ3  1 
ATOM   288  C CH2  . TRP A 1 19  ? 22.53961 27.23287 11.88113  1.000 41.83906  ? 19  TRP A CH2  1 
ATOM   289  H H    . TRP A 1 19  ? 23.01510 22.73353 6.69599   1.000 40.98305  ? 19  TRP A H    1 
ATOM   290  H HA   . TRP A 1 19  ? 24.11989 23.01165 9.11041   1.000 40.72264  ? 19  TRP A HA   1 
ATOM   291  H HB2  . TRP A 1 19  ? 21.50426 22.34664 8.32610   1.000 42.19331  ? 19  TRP A HB2  1 
ATOM   292  H HB3  . TRP A 1 19  ? 21.93859 22.30763 9.85426   1.000 42.19331  ? 19  TRP A HB3  1 
ATOM   293  H HD1  . TRP A 1 19  ? 20.68729 24.63319 7.45197   1.000 43.83802  ? 19  TRP A HD1  1 
ATOM   294  H HE1  . TRP A 1 19  ? 20.55850 26.87951 8.30565   1.000 44.07484  ? 19  TRP A HE1  1 
ATOM   295  H HE3  . TRP A 1 19  ? 23.24383 24.05640 11.59210  1.000 42.14761  ? 19  TRP A HE3  1 
ATOM   296  H HZ2  . TRP A 1 19  ? 21.46866 28.26514 10.52360  1.000 45.21951  ? 19  TRP A HZ2  1 
ATOM   297  H HZ3  . TRP A 1 19  ? 23.55652 25.87494 12.99085  1.000 48.67427  ? 19  TRP A HZ3  1 
ATOM   298  H HH2  . TRP A 1 19  ? 22.67905 27.94786 12.45927  1.000 50.20687  ? 19  TRP A HH2  1 
ATOM   299  N N    . VAL A 1 20  ? 25.11379 20.76746 9.35723   1.000 34.97933  ? 20  VAL A N    1 
ATOM   300  C CA   . VAL A 1 20  ? 25.52461 19.41259 9.70892   1.000 35.97353  ? 20  VAL A CA   1 
ATOM   301  C C    . VAL A 1 20  ? 24.69622 18.90378 10.87965  1.000 42.58154  ? 20  VAL A C    1 
ATOM   302  O O    . VAL A 1 20  ? 24.29121 17.73538 10.91744  1.000 40.94142  ? 20  VAL A O    1 
ATOM   303  C CB   . VAL A 1 20  ? 27.03097 19.37860 10.03007  1.000 34.14827  ? 20  VAL A CB   1 
ATOM   304  C CG1  . VAL A 1 20  ? 27.46950 17.96651 10.39675  1.000 36.39057  ? 20  VAL A CG1  1 
ATOM   305  C CG2  . VAL A 1 20  ? 27.84029 19.91237 8.85771   1.000 37.37904  ? 20  VAL A CG2  1 
ATOM   306  H H    . VAL A 1 20  ? 25.69736 21.37525 9.52937   1.000 41.97520  ? 20  VAL A H    1 
ATOM   307  H HA   . VAL A 1 20  ? 25.36713 18.83203 8.94797   1.000 43.16824  ? 20  VAL A HA   1 
ATOM   308  H HB   . VAL A 1 20  ? 27.20107 19.95091 10.79455  1.000 40.97792  ? 20  VAL A HB   1 
ATOM   309  H HG11 . VAL A 1 20  ? 26.74085 17.35244 10.21541  1.000 43.66868  ? 20  VAL A HG11 1 
ATOM   310  H HG12 . VAL A 1 20  ? 28.24377 17.72778 9.86344   1.000 43.66868  ? 20  VAL A HG12 1 
ATOM   311  H HG13 . VAL A 1 20  ? 27.69660 17.94114 11.33945  1.000 43.66868  ? 20  VAL A HG13 1 
ATOM   312  H HG21 . VAL A 1 20  ? 28.78449 19.84776 9.07031   1.000 44.85484  ? 20  VAL A HG21 1 
ATOM   313  H HG22 . VAL A 1 20  ? 27.64167 19.38279 8.06969   1.000 44.85484  ? 20  VAL A HG22 1 
ATOM   314  H HG23 . VAL A 1 20  ? 27.59871 20.83899 8.70304   1.000 44.85484  ? 20  VAL A HG23 1 
ATOM   315  N N    . SER A 1 21  ? 24.43973 19.77017 11.85325  1.000 42.01413  ? 21  SER A N    1 
ATOM   316  C CA   . SER A 1 21  ? 23.61447 19.46120 13.01089  1.000 45.31449  ? 21  SER A CA   1 
ATOM   317  C C    . SER A 1 21  ? 22.79730 20.70404 13.34217  1.000 40.44234  ? 21  SER A C    1 
ATOM   318  O O    . SER A 1 21  ? 22.93240 21.73271 12.66705  1.000 38.05379  ? 21  SER A O    1 
ATOM   319  C CB   . SER A 1 21  ? 24.47123 19.04818 14.20411  1.000 42.82429  ? 21  SER A CB   1 
ATOM   320  O OG   . SER A 1 21  ? 24.84577 20.18051 14.96786  1.000 42.68492  ? 21  SER A OG   1 
ATOM   321  H H    . SER A 1 21  ? 24.74444 20.57428 11.86591  1.000 50.41696  ? 21  SER A H    1 
ATOM   322  H HA   . SER A 1 21  ? 23.02216 18.71792 12.81699  1.000 54.37739  ? 21  SER A HA   1 
ATOM   323  H HB2  . SER A 1 21  ? 23.96145 18.44290 14.76506  1.000 51.38915  ? 21  SER A HB2  1 
ATOM   324  H HB3  . SER A 1 21  ? 25.27171 18.60598 13.88072  1.000 51.38915  ? 21  SER A HB3  1 
ATOM   325  H HG   . SER A 1 21  ? 25.31114 19.94241 15.62538  1.000 51.22191  ? 21  SER A HG   1 
ATOM   326  N N    . PRO A 1 22  ? 21.93996 20.65586 14.36218  1.000 38.71455  ? 22  PRO A N    1 
ATOM   327  C CA   . PRO A 1 22  ? 21.24355 21.88685 14.77179  1.000 40.39054  ? 22  PRO A CA   1 
ATOM   328  C C    . PRO A 1 22  ? 22.18238 23.02764 15.13094  1.000 43.73807  ? 22  PRO A C    1 
ATOM   329  O O    . PRO A 1 22  ? 21.80120 24.19595 14.98498  1.000 45.40272  ? 22  PRO A O    1 
ATOM   330  C CB   . PRO A 1 22  ? 20.41276 21.42989 15.98082  1.000 45.68161  ? 22  PRO A CB   1 
ATOM   331  C CG   . PRO A 1 22  ? 20.15620 19.98004 15.72869  1.000 44.56769  ? 22  PRO A CG   1 
ATOM   332  C CD   . PRO A 1 22  ? 21.38503 19.45438 15.01451  1.000 47.81805  ? 22  PRO A CD   1 
ATOM   333  H HA   . PRO A 1 22  ? 20.64765 22.17957 14.06460  1.000 48.46864  ? 22  PRO A HA   1 
ATOM   334  H HB2  . PRO A 1 22  ? 20.91780 21.55814 16.79898  1.000 54.81793  ? 22  PRO A HB2  1 
ATOM   335  H HB3  . PRO A 1 22  ? 19.58239 21.92960 16.02173  1.000 54.81793  ? 22  PRO A HB3  1 
ATOM   336  H HG2  . PRO A 1 22  ? 20.02736 19.51992 16.57284  1.000 53.48123  ? 22  PRO A HG2  1 
ATOM   337  H HG3  . PRO A 1 22  ? 19.36769 19.88014 15.17266  1.000 53.48123  ? 22  PRO A HG3  1 
ATOM   338  H HD2  . PRO A 1 22  ? 22.01872 19.08151 15.64721  1.000 57.38166  ? 22  PRO A HD2  1 
ATOM   339  H HD3  . PRO A 1 22  ? 21.14144 18.78546 14.35564  1.000 57.38166  ? 22  PRO A HD3  1 
ATOM   340  N N    . SER A 1 23  ? 23.40390 22.72844 15.57841  1.000 45.20381  ? 23  SER A N    1 
ATOM   341  C CA   . SER A 1 23  ? 24.32617 23.74867 16.05283  1.000 44.49760  ? 23  SER A CA   1 
ATOM   342  C C    . SER A 1 23  ? 25.52728 23.96719 15.14282  1.000 45.32321  ? 23  SER A C    1 
ATOM   343  O O    . SER A 1 23  ? 26.21362 24.98473 15.29424  1.000 41.23194  ? 23  SER A O    1 
ATOM   344  C CB   . SER A 1 23  ? 24.83080 23.39181 17.46267  1.000 43.11123  ? 23  SER A CB   1 
ATOM   345  O OG   . SER A 1 23  ? 23.78037 23.42687 18.41330  1.000 61.64578  ? 23  SER A OG   1 
ATOM   346  H H    . SER A 1 23  ? 23.72104 21.92992 15.61559  1.000 54.24457  ? 23  SER A H    1 
ATOM   347  H HA   . SER A 1 23  ? 23.84456 24.58902 16.10544  1.000 53.39712  ? 23  SER A HA   1 
ATOM   348  H HB2  . SER A 1 23  ? 25.20676 22.49783 17.44394  1.000 51.73348  ? 23  SER A HB2  1 
ATOM   349  H HB3  . SER A 1 23  ? 25.51095 24.03234 17.72348  1.000 51.73348  ? 23  SER A HB3  1 
ATOM   350  H HG   . SER A 1 23  ? 24.08485 23.28527 19.18326  1.000 73.97493  ? 23  SER A HG   1 
ATOM   351  N N    . LEU A 1 24  ? 25.79873 23.06178 14.20599  1.000 46.16310  ? 24  LEU A N    1 
ATOM   352  C CA   . LEU A 1 24  ? 26.98281 23.14303 13.36059  1.000 41.50801  ? 24  LEU A CA   1 
ATOM   353  C C    . LEU A 1 24  ? 26.58236 23.45876 11.92512  1.000 34.21605  ? 24  LEU A C    1 
ATOM   354  O O    . LEU A 1 24  ? 25.66373 22.84061 11.37718  1.000 39.59018  ? 24  LEU A O    1 
ATOM   355  C CB   . LEU A 1 24  ? 27.78316 21.84001 13.40540  1.000 45.11615  ? 24  LEU A CB   1 
ATOM   356  C CG   . LEU A 1 24  ? 29.23044 21.97947 12.92813  1.000 51.73655  ? 24  LEU A CG   1 
ATOM   357  C CD1  . LEU A 1 24  ? 30.03224 22.79465 13.93437  1.000 55.00174  ? 24  LEU A CD1  1 
ATOM   358  C CD2  . LEU A 1 24  ? 29.86226 20.61878 12.70352  1.000 51.24047  ? 24  LEU A CD2  1 
ATOM   359  H H    . LEU A 1 24  ? 25.30165 22.37990 14.04000  1.000 55.39572  ? 24  LEU A H    1 
ATOM   360  H HA   . LEU A 1 24  ? 27.54674 23.86421 13.68118  1.000 49.80962  ? 24  LEU A HA   1 
ATOM   361  H HB2  . LEU A 1 24  ? 27.80353 21.52015 14.32092  1.000 54.13938  ? 24  LEU A HB2  1 
ATOM   362  H HB3  . LEU A 1 24  ? 27.34580 21.18794 12.83582  1.000 54.13938  ? 24  LEU A HB3  1 
ATOM   363  H HG   . LEU A 1 24  ? 29.24323 22.44584 12.07770  1.000 62.08386  ? 24  LEU A HG   1 
ATOM   364  H HD11 . LEU A 1 24  ? 29.48061 22.96517 14.71381  1.000 66.00209  ? 24  LEU A HD11 1 
ATOM   365  H HD12 . LEU A 1 24  ? 30.82113 22.29196 14.19102  1.000 66.00209  ? 24  LEU A HD12 1 
ATOM   366  H HD13 . LEU A 1 24  ? 30.29372 23.63386 13.52418  1.000 66.00209  ? 24  LEU A HD13 1 
ATOM   367  H HD21 . LEU A 1 24  ? 29.28916 20.09685 12.12038  1.000 61.48857  ? 24  LEU A HD21 1 
ATOM   368  H HD22 . LEU A 1 24  ? 30.73218 20.73866 12.29148  1.000 61.48857  ? 24  LEU A HD22 1 
ATOM   369  H HD23 . LEU A 1 24  ? 29.96006 20.17100 13.55840  1.000 61.48857  ? 24  LEU A HD23 1 
ATOM   370  N N    . PHE A 1 25  ? 27.29286 24.40548 11.31799  1.000 36.86051  ? 25  PHE A N    1 
ATOM   371  C CA   . PHE A 1 25  ? 26.97525 24.93324 9.99437   1.000 32.68495  ? 25  PHE A CA   1 
ATOM   372  C C    . PHE A 1 25  ? 28.28598 25.10435 9.24457   1.000 32.35101  ? 25  PHE A C    1 
ATOM   373  O O    . PHE A 1 25  ? 29.16154 25.84606 9.69853   1.000 33.98420  ? 25  PHE A O    1 
ATOM   374  C CB   . PHE A 1 25  ? 26.22520 26.26306 10.13232  1.000 31.47842  ? 25  PHE A CB   1 
ATOM   375  C CG   . PHE A 1 25  ? 25.70879 26.83511 8.84095   1.000 31.92229  ? 25  PHE A CG   1 
ATOM   376  C CD1  . PHE A 1 25  ? 24.60679 26.28367 8.20536   1.000 34.85266  ? 25  PHE A CD1  1 
ATOM   377  C CD2  . PHE A 1 25  ? 26.29377 27.96554 8.29269   1.000 34.90149  ? 25  PHE A CD2  1 
ATOM   378  C CE1  . PHE A 1 25  ? 24.12030 26.82935 7.03057   1.000 33.95996  ? 25  PHE A CE1  1 
ATOM   379  C CE2  . PHE A 1 25  ? 25.81165 28.51619 7.11944   1.000 36.25772  ? 25  PHE A CE2  1 
ATOM   380  C CZ   . PHE A 1 25  ? 24.71960 27.95012 6.49141   1.000 32.11693  ? 25  PHE A CZ   1 
ATOM   381  H H    . PHE A 1 25  ? 27.98925 24.77154 11.66531  1.000 44.23262  ? 25  PHE A H    1 
ATOM   382  H HA   . PHE A 1 25  ? 26.41803 24.31990 9.49017   1.000 39.22194  ? 25  PHE A HA   1 
ATOM   383  H HB2  . PHE A 1 25  ? 25.46261 26.12688 10.71612  1.000 37.77411  ? 25  PHE A HB2  1 
ATOM   384  H HB3  . PHE A 1 25  ? 26.82746 26.91699 10.52033  1.000 37.77411  ? 25  PHE A HB3  1 
ATOM   385  H HD1  . PHE A 1 25  ? 24.18966 25.53819 8.57301   1.000 41.82319  ? 25  PHE A HD1  1 
ATOM   386  H HD2  . PHE A 1 25  ? 27.02029 28.35906 8.71955   1.000 41.88179  ? 25  PHE A HD2  1 
ATOM   387  H HE1  . PHE A 1 25  ? 23.39027 26.44148 6.60454   1.000 40.75196  ? 25  PHE A HE1  1 
ATOM   388  H HE2  . PHE A 1 25  ? 26.22206 29.26642 6.75390   1.000 43.50926  ? 25  PHE A HE2  1 
ATOM   389  H HZ   . PHE A 1 25  ? 24.38848 28.32333 5.70657   1.000 38.54032  ? 25  PHE A HZ   1 
ATOM   390  N N    . ILE A 1 26  ? 28.43282 24.40829 8.11704   1.000 30.87254  ? 26  ILE A N    1 
ATOM   391  C CA   . ILE A 1 26  ? 29.66800 24.43581 7.34351   1.000 28.41037  ? 26  ILE A CA   1 
ATOM   392  C C    . ILE A 1 26  ? 29.42771 25.20265 6.04956   1.000 33.01700  ? 26  ILE A C    1 
ATOM   393  O O    . ILE A 1 26  ? 28.33089 25.17734 5.47842   1.000 32.21083  ? 26  ILE A O    1 
ATOM   394  C CB   . ILE A 1 26  ? 30.21012 23.01942 7.04992   1.000 28.22025  ? 26  ILE A CB   1 
ATOM   395  C CG1  . ILE A 1 26  ? 29.21013 22.18077 6.24725   1.000 31.05405  ? 26  ILE A CG1  1 
ATOM   396  C CG2  . ILE A 1 26  ? 30.55641 22.30774 8.35543   1.000 32.28616  ? 26  ILE A CG2  1 
ATOM   397  C CD1  . ILE A 1 26  ? 29.75260 20.80516 5.84707   1.000 31.56255  ? 26  ILE A CD1  1 
ATOM   398  H H    . ILE A 1 26  ? 27.82166 23.90721 7.77794   1.000 37.04705  ? 26  ILE A H    1 
ATOM   399  H HA   . ILE A 1 26  ? 30.34069 24.91017 7.85671   1.000 34.09245  ? 26  ILE A HA   1 
ATOM   400  H HB   . ILE A 1 26  ? 31.01040 23.12198 6.51147   1.000 33.86431  ? 26  ILE A HB   1 
ATOM   401  H HG12 . ILE A 1 26  ? 28.41486 22.04206 6.78503   1.000 37.26486  ? 26  ILE A HG12 1 
ATOM   402  H HG13 . ILE A 1 26  ? 28.98187 22.65854 5.43452   1.000 37.26486  ? 26  ILE A HG13 1 
ATOM   403  H HG21 . ILE A 1 26  ? 31.16854 22.86189 8.86445   1.000 38.74339  ? 26  ILE A HG21 1 
ATOM   404  H HG22 . ILE A 1 26  ? 29.74191 22.16316 8.86196   1.000 38.74339  ? 26  ILE A HG22 1 
ATOM   405  H HG23 . ILE A 1 26  ? 30.97368 21.45651 8.15001   1.000 38.74339  ? 26  ILE A HG23 1 
ATOM   406  H HD11 . ILE A 1 26  ? 29.12162 20.37962 5.24567   1.000 37.87506  ? 26  ILE A HD11 1 
ATOM   407  H HD12 . ILE A 1 26  ? 30.60724 20.91975 5.40283   1.000 37.87506  ? 26  ILE A HD12 1 
ATOM   408  H HD13 . ILE A 1 26  ? 29.86441 20.26538 6.64521   1.000 37.87506  ? 26  ILE A HD13 1 
ATOM   409  N N    . THR A 1 27  ? 30.46521 25.89763 5.59147   1.000 34.32367  ? 27  THR A N    1 
ATOM   410  C CA   . THR A 1 27  ? 30.38630 26.68151 4.36568   1.000 34.78394  ? 27  THR A CA   1 
ATOM   411  C C    . THR A 1 27  ? 31.79610 26.87524 3.81959   1.000 31.62585  ? 27  THR A C    1 
ATOM   412  O O    . THR A 1 27  ? 32.77249 26.34348 4.35574   1.000 33.61646  ? 27  THR A O    1 
ATOM   413  C CB   . THR A 1 27  ? 29.69701 28.02934 4.61051   1.000 33.22285  ? 27  THR A CB   1 
ATOM   414  O OG1  . THR A 1 27  ? 29.48407 28.69846 3.36161   1.000 28.74927  ? 27  THR A OG1  1 
ATOM   415  C CG2  . THR A 1 27  ? 30.54819 28.91262 5.51301   1.000 31.44602  ? 27  THR A CG2  1 
ATOM   416  H H    . THR A 1 27  ? 31.23295 25.93063 5.97760   1.000 41.18841  ? 27  THR A H    1 
ATOM   417  H HA   . THR A 1 27  ? 29.87016 26.18315 3.71289   1.000 41.74072  ? 27  THR A HA   1 
ATOM   418  H HB   . THR A 1 27  ? 28.84374 27.87717 5.04602   1.000 39.86742  ? 27  THR A HB   1 
ATOM   419  H HG1  . THR A 1 27  ? 28.92534 28.27397 2.89985   1.000 34.49913  ? 27  THR A HG1  1 
ATOM   420  H HG21 . THR A 1 27  ? 31.31533 29.24671 5.02232   1.000 37.73523  ? 27  THR A HG21 1 
ATOM   421  H HG22 . THR A 1 27  ? 30.02483 29.66543 5.82965   1.000 37.73523  ? 27  THR A HG22 1 
ATOM   422  H HG23 . THR A 1 27  ? 30.86070 28.40296 6.27687   1.000 37.73523  ? 27  THR A HG23 1 
ATOM   423  N N    . SER A 1 28  ? 31.88981 27.64367 2.73814   1.000 30.16460  ? 28  SER A N    1 
ATOM   424  C CA   . SER A 1 28  ? 33.16662 27.98086 2.12808   1.000 33.11621  ? 28  SER A CA   1 
ATOM   425  C C    . SER A 1 28  ? 33.67303 29.30609 2.67957   1.000 32.78816  ? 28  SER A C    1 
ATOM   426  O O    . SER A 1 28  ? 32.89618 30.23650 2.90930   1.000 29.92182  ? 28  SER A O    1 
ATOM   427  C CB   . SER A 1 28  ? 33.02834 28.06496 0.60751   1.000 31.50530  ? 28  SER A CB   1 
ATOM   428  O OG   . SER A 1 28  ? 33.95676 28.98262 0.05463   1.000 39.35420  ? 28  SER A OG   1 
ATOM   429  H H    . SER A 1 28  ? 31.21355 27.98747 2.33307   1.000 36.19752  ? 28  SER A H    1 
ATOM   430  H HA   . SER A 1 28  ? 33.81876 27.29327 2.33502   1.000 39.73945  ? 28  SER A HA   1 
ATOM   431  H HB2  . SER A 1 28  ? 33.19148 27.18704 0.22865   1.000 37.80636  ? 28  SER A HB2  1 
ATOM   432  H HB3  . SER A 1 28  ? 32.12975 28.35841 0.38999   1.000 37.80636  ? 28  SER A HB3  1 
ATOM   433  H HG   . SER A 1 28  ? 33.68779 29.76961 0.17254   1.000 47.22504  ? 28  SER A HG   1 
ATOM   434  N N    . THR A 1 29  ? 34.98620 29.38258 2.89710   1.000 32.58689  ? 29  THR A N    1 
ATOM   435  C CA   . THR A 1 29  ? 35.58248 30.63219 3.35295   1.000 37.43237  ? 29  THR A CA   1 
ATOM   436  C C    . THR A 1 29  ? 35.31499 31.76803 2.37293   1.000 34.11725  ? 29  THR A C    1 
ATOM   437  O O    . THR A 1 29  ? 35.14098 32.91873 2.78868   1.000 36.10706  ? 29  THR A O    1 
ATOM   438  C CB   . THR A 1 29  ? 37.08646 30.44429 3.55156   1.000 32.63818  ? 29  THR A CB   1 
ATOM   439  O OG1  . THR A 1 29  ? 37.31738 29.37290 4.47563   1.000 36.97718  ? 29  THR A OG1  1 
ATOM   440  C CG2  . THR A 1 29  ? 37.72089 31.71590 4.08366   1.000 37.94393  ? 29  THR A CG2  1 
ATOM   441  H H    . THR A 1 29  ? 35.54296 28.73599 2.78975   1.000 39.10427  ? 29  THR A H    1 
ATOM   442  H HA   . THR A 1 29  ? 35.19236 30.87638 4.20681   1.000 44.91885  ? 29  THR A HA   1 
ATOM   443  H HB   . THR A 1 29  ? 37.50055 30.23293 2.70023   1.000 39.16582  ? 29  THR A HB   1 
ATOM   444  H HG1  . THR A 1 29  ? 38.14059 29.21627 4.53402   1.000 44.37262  ? 29  THR A HG1  1 
ATOM   445  H HG21 . THR A 1 29  ? 37.21519 32.04657 4.84249   1.000 45.53272  ? 29  THR A HG21 1 
ATOM   446  H HG22 . THR A 1 29  ? 38.63208 31.53925 4.36548   1.000 45.53272  ? 29  THR A HG22 1 
ATOM   447  H HG23 . THR A 1 29  ? 37.73152 32.39591 3.39202   1.000 45.53272  ? 29  THR A HG23 1 
ATOM   448  N N    . HIS A 1 30  ? 35.26448 31.46535 1.07395   1.000 34.84351  ? 30  HIS A N    1 
ATOM   449  C CA   . HIS A 1 30  ? 35.07541 32.50295 0.06996   1.000 35.95735  ? 30  HIS A CA   1 
ATOM   450  C C    . HIS A 1 30  ? 33.70765 33.16911 0.15004   1.000 40.44058  ? 30  HIS A C    1 
ATOM   451  O O    . HIS A 1 30  ? 33.55032 34.28215 -0.36398  1.000 38.88686  ? 30  HIS A O    1 
ATOM   452  C CB   . HIS A 1 30  ? 35.26652 31.91777 -1.33293  1.000 34.96782  ? 30  HIS A CB   1 
ATOM   453  C CG   . HIS A 1 30  ? 36.59781 32.22747 -1.94016  1.000 40.89636  ? 30  HIS A CG   1 
ATOM   454  N ND1  . HIS A 1 30  ? 37.76728 31.63970 -1.50925  1.000 42.31821  ? 30  HIS A ND1  1 
ATOM   455  C CD2  . HIS A 1 30  ? 36.94674 33.07301 -2.93848  1.000 41.20775  ? 30  HIS A CD2  1 
ATOM   456  C CE1  . HIS A 1 30  ? 38.77923 32.10721 -2.21857  1.000 46.45181  ? 30  HIS A CE1  1 
ATOM   457  N NE2  . HIS A 1 30  ? 38.30862 32.97803 -3.09311  1.000 43.79524  ? 30  HIS A NE2  1 
ATOM   458  H H    . HIS A 1 30  ? 35.33697 30.67067 0.75328   1.000 41.81221  ? 30  HIS A H    1 
ATOM   459  H HA   . HIS A 1 30  ? 35.74802 33.18598 0.21815   1.000 43.14882  ? 30  HIS A HA   1 
ATOM   460  H HB2  . HIS A 1 30  ? 35.18174 30.95281 -1.28232  1.000 41.96138  ? 30  HIS A HB2  1 
ATOM   461  H HB3  . HIS A 1 30  ? 34.58301 32.28064 -1.91776  1.000 41.96138  ? 30  HIS A HB3  1 
ATOM   462  H HD1  . HIS A 1 30  ? 37.82885 31.05941 -0.87753  1.000 50.78185  ? 30  HIS A HD1  1 
ATOM   463  H HD2  . HIS A 1 30  ? 36.37214 33.61635 -3.42789  1.000 49.44930  ? 30  HIS A HD2  1 
ATOM   464  H HE1  . HIS A 1 30  ? 39.67142 31.86436 -2.11898  1.000 55.74217  ? 30  HIS A HE1  1 
ATOM   465  N N    . VAL A 1 31  ? 32.72144 32.52983 0.77619   1.000 35.64753  ? 31  VAL A N    1 
ATOM   466  C CA   . VAL A 1 31  ? 31.35216 33.02464 0.73746   1.000 37.52511  ? 31  VAL A CA   1 
ATOM   467  C C    . VAL A 1 31  ? 30.88087 33.61305 2.06407   1.000 37.79014  ? 31  VAL A C    1 
ATOM   468  O O    . VAL A 1 31  ? 29.91952 34.39778 2.06054   1.000 39.20204  ? 31  VAL A O    1 
ATOM   469  C CB   . VAL A 1 31  ? 30.37245 31.92275 0.27494   1.000 37.01488  ? 31  VAL A CB   1 
ATOM   470  C CG1  . VAL A 1 31  ? 30.90260 31.22601 -0.97113  1.000 41.43107  ? 31  VAL A CG1  1 
ATOM   471  C CG2  . VAL A 1 31  ? 30.10913 30.91625 1.39145   1.000 30.72037  ? 31  VAL A CG2  1 
ATOM   472  H H    . VAL A 1 31  ? 32.82234 31.80647 1.23026   1.000 42.77704  ? 31  VAL A H    1 
ATOM   473  H HA   . VAL A 1 31  ? 31.32026 33.74452 0.08810   1.000 45.03013  ? 31  VAL A HA   1 
ATOM   474  H HB   . VAL A 1 31  ? 29.52498 32.33831 0.05134   1.000 44.41786  ? 31  VAL A HB   1 
ATOM   475  H HG11 . VAL A 1 31  ? 30.22188 30.62375 -1.30996  1.000 49.71728  ? 31  VAL A HG11 1 
ATOM   476  H HG12 . VAL A 1 31  ? 31.11535 31.89493 -1.64060  1.000 49.71728  ? 31  VAL A HG12 1 
ATOM   477  H HG13 . VAL A 1 31  ? 31.70038 30.72590 -0.73803  1.000 49.71728  ? 31  VAL A HG13 1 
ATOM   478  H HG21 . VAL A 1 31  ? 30.82524 30.97313 2.04326   1.000 36.86445  ? 31  VAL A HG21 1 
ATOM   479  H HG22 . VAL A 1 31  ? 29.26101 31.12652 1.81262   1.000 36.86445  ? 31  VAL A HG22 1 
ATOM   480  H HG23 . VAL A 1 31  ? 30.07768 30.02428 1.01160   1.000 36.86445  ? 31  VAL A HG23 1 
ATOM   481  N N    . ILE A 1 32  ? 31.50917 33.27362 3.18633   1.000 34.52734  ? 32  ILE A N    1 
ATOM   482  C CA   . ILE A 1 32  ? 30.99201 33.76076 4.47359   1.000 37.88431  ? 32  ILE A CA   1 
ATOM   483  C C    . ILE A 1 32  ? 31.03033 35.28673 4.49070   1.000 38.94741  ? 32  ILE A C    1 
ATOM   484  O O    . ILE A 1 32  ? 32.08517 35.88411 4.19809   1.000 38.18486  ? 32  ILE A O    1 
ATOM   485  C CB   . ILE A 1 32  ? 31.80153 33.17102 5.64774   1.000 36.73425  ? 32  ILE A CB   1 
ATOM   486  C CG1  . ILE A 1 32  ? 31.25714 33.71233 6.97571   1.000 39.07358  ? 32  ILE A CG1  1 
ATOM   487  C CG2  . ILE A 1 32  ? 33.28552 33.48183 5.50587   1.000 40.99718  ? 32  ILE A CG2  1 
ATOM   488  C CD1  . ILE A 1 32  ? 31.97415 33.19884 8.20785   1.000 36.75111  ? 32  ILE A CD1  1 
ATOM   489  H H    . ILE A 1 32  ? 32.21207 32.78049 3.23495   1.000 41.43281  ? 32  ILE A H    1 
ATOM   490  H HA   . ILE A 1 32  ? 30.06921 33.47852 4.57199   1.000 45.46117  ? 32  ILE A HA   1 
ATOM   491  H HB   . ILE A 1 32  ? 31.70128 32.20631 5.63387   1.000 44.08111  ? 32  ILE A HB   1 
ATOM   492  H HG12 . ILE A 1 32  ? 31.33862 34.67889 6.97152   1.000 46.88829  ? 32  ILE A HG12 1 
ATOM   493  H HG13 . ILE A 1 32  ? 30.32419 33.45837 7.05319   1.000 46.88829  ? 32  ILE A HG13 1 
ATOM   494  H HG21 . ILE A 1 32  ? 33.77511 33.00611 6.19500   1.000 49.19662  ? 32  ILE A HG21 1 
ATOM   495  H HG22 . ILE A 1 32  ? 33.58578 33.19529 4.62915   1.000 49.19662  ? 32  ILE A HG22 1 
ATOM   496  H HG23 . ILE A 1 32  ? 33.41893 34.43747 5.60519   1.000 49.19662  ? 32  ILE A HG23 1 
ATOM   497  H HD11 . ILE A 1 32  ? 31.51850 33.52782 8.99846   1.000 44.10133  ? 32  ILE A HD11 1 
ATOM   498  H HD12 . ILE A 1 32  ? 31.96243 32.22896 8.19884   1.000 44.10133  ? 32  ILE A HD12 1 
ATOM   499  H HD13 . ILE A 1 32  ? 32.88983 33.51870 8.19665   1.000 44.10133  ? 32  ILE A HD13 1 
ATOM   500  N N    . PRO A 1 33  ? 29.92826 35.96549 4.81706   1.000 38.44860  ? 33  PRO A N    1 
ATOM   501  C CA   . PRO A 1 33  ? 29.95113 37.43635 4.85927   1.000 41.36315  ? 33  PRO A CA   1 
ATOM   502  C C    . PRO A 1 33  ? 30.89588 37.95114 5.93614   1.000 37.54353  ? 33  PRO A C    1 
ATOM   503  O O    . PRO A 1 33  ? 30.80404 37.56801 7.10395   1.000 39.22366  ? 33  PRO A O    1 
ATOM   504  C CB   . PRO A 1 33  ? 28.49134 37.80777 5.15991   1.000 41.83242  ? 33  PRO A CB   1 
ATOM   505  C CG   . PRO A 1 33  ? 27.69078 36.60509 4.75786   1.000 42.03773  ? 33  PRO A CG   1 
ATOM   506  C CD   . PRO A 1 33  ? 28.57291 35.42494 5.03632   1.000 37.75989  ? 33  PRO A CD   1 
ATOM   507  H HA   . PRO A 1 33  ? 30.21322 37.79648 3.99758   1.000 49.63578  ? 33  PRO A HA   1 
ATOM   508  H HB2  . PRO A 1 33  ? 28.38662 37.99342 6.10621   1.000 50.19890  ? 33  PRO A HB2  1 
ATOM   509  H HB3  . PRO A 1 33  ? 28.23494 38.58485 4.63903   1.000 50.19890  ? 33  PRO A HB3  1 
ATOM   510  H HG2  . PRO A 1 33  ? 26.87798 36.56010 5.28534   1.000 50.44528  ? 33  PRO A HG2  1 
ATOM   511  H HG3  . PRO A 1 33  ? 27.47156 36.65671 3.81437   1.000 50.44528  ? 33  PRO A HG3  1 
ATOM   512  H HD2  . PRO A 1 33  ? 28.46526 35.12006 5.95084   1.000 45.31187  ? 33  PRO A HD2  1 
ATOM   513  H HD3  . PRO A 1 33  ? 28.38549 34.69934 4.42047   1.000 45.31187  ? 33  PRO A HD3  1 
ATOM   514  N N    . GLN A 1 34  ? 31.80411 38.84483 5.53063   1.000 38.31951  ? 34  GLN A N    1 
ATOM   515  C CA   . GLN A 1 34  ? 32.84010 39.35823 6.41783   1.000 44.00609  ? 34  GLN A CA   1 
ATOM   516  C C    . GLN A 1 34  ? 32.41755 40.59131 7.20570   1.000 44.43141  ? 34  GLN A C    1 
ATOM   517  O O    . GLN A 1 34  ? 33.09060 40.94149 8.18315   1.000 42.90640  ? 34  GLN A O    1 
ATOM   518  C CB   . GLN A 1 34  ? 34.09707 39.70121 5.60789   1.000 48.63984  ? 34  GLN A CB   1 
ATOM   519  C CG   . GLN A 1 34  ? 34.69428 38.51808 4.87327   1.000 49.09816  ? 34  GLN A CG   1 
ATOM   520  C CD   . GLN A 1 34  ? 35.23237 37.47250 5.82115   1.000 43.31739  ? 34  GLN A CD   1 
ATOM   521  O OE1  . GLN A 1 34  ? 34.63539 36.41096 5.99565   1.000 45.53904  ? 34  GLN A OE1  1 
ATOM   522  N NE2  . GLN A 1 34  ? 36.36336 37.76939 6.44660   1.000 40.19371  ? 34  GLN A NE2  1 
ATOM   523  H H    . GLN A 1 34  ? 31.83808 39.17065 4.73547   1.000 45.98341  ? 34  GLN A H    1 
ATOM   524  H HA   . GLN A 1 34  ? 33.06074 38.66339 7.05768   1.000 52.80731  ? 34  GLN A HA   1 
ATOM   525  H HB2  . GLN A 1 34  ? 33.86830 40.37429 4.94794   1.000 58.36780  ? 34  GLN A HB2  1 
ATOM   526  H HB3  . GLN A 1 34  ? 34.77282 40.04565 6.21255   1.000 58.36780  ? 34  GLN A HB3  1 
ATOM   527  H HG2  . GLN A 1 34  ? 34.00930 38.10515 4.32445   1.000 58.91779  ? 34  GLN A HG2  1 
ATOM   528  H HG3  . GLN A 1 34  ? 35.42566 38.82576 4.31531   1.000 58.91779  ? 34  GLN A HG3  1 
ATOM   529  H HE21 . GLN A 1 34  ? 36.74936 38.52417 6.30200   1.000 48.23246  ? 34  GLN A HE21 1 
ATOM   530  H HE22 . GLN A 1 34  ? 36.71085 37.20715 6.99681   1.000 48.23246  ? 34  GLN A HE22 1 
ATOM   531  N N    . GLY A 1 35  ? 31.34154 41.26126 6.81085   1.000 42.21909  ? 35  GLY A N    1 
ATOM   532  C CA   . GLY A 1 35  ? 30.86244 42.43548 7.50416   1.000 48.52967  ? 35  GLY A CA   1 
ATOM   533  C C    . GLY A 1 35  ? 29.64014 42.21629 8.37322   1.000 45.58498  ? 35  GLY A C    1 
ATOM   534  O O    . GLY A 1 35  ? 29.07221 43.18844 8.87120   1.000 50.04089  ? 35  GLY A O    1 
ATOM   535  H H    . GLY A 1 35  ? 30.86577 41.04510 6.12784   1.000 50.66291  ? 35  GLY A H    1 
ATOM   536  H HA2  . GLY A 1 35  ? 31.57285 42.76985 8.07373   1.000 58.23561  ? 35  GLY A HA2  1 
ATOM   537  H HA3  . GLY A 1 35  ? 30.63912 43.11315 6.84705   1.000 58.23561  ? 35  GLY A HA3  1 
ATOM   538  N N    . ALA A 1 36  ? 29.23241 40.96600 8.57260   1.000 44.41673  ? 36  ALA A N    1 
ATOM   539  C CA   . ALA A 1 36  ? 28.00226 40.67813 9.29378   1.000 43.07768  ? 36  ALA A CA   1 
ATOM   540  C C    . ALA A 1 36  ? 28.20687 40.78418 10.79828  1.000 46.23259  ? 36  ALA A C    1 
ATOM   541  O O    . ALA A 1 36  ? 29.22672 40.34520 11.33742  1.000 49.69168  ? 36  ALA A O    1 
ATOM   542  C CB   . ALA A 1 36  ? 27.49660 39.27879 8.93852   1.000 39.08533  ? 36  ALA A CB   1 
ATOM   543  H H    . ALA A 1 36  ? 29.65256 40.26730 8.29893   1.000 53.30008  ? 36  ALA A H    1 
ATOM   544  H HA   . ALA A 1 36  ? 27.32866 41.32790 9.03889   1.000 51.69322  ? 36  ALA A HA   1 
ATOM   545  H HB1  . ALA A 1 36  ? 26.67810 39.10478 9.42910   1.000 46.90240  ? 36  ALA A HB1  1 
ATOM   546  H HB2  . ALA A 1 36  ? 27.32563 39.23752 7.98459   1.000 46.90240  ? 36  ALA A HB2  1 
ATOM   547  H HB3  . ALA A 1 36  ? 28.17291 38.62740 9.18183   1.000 46.90240  ? 36  ALA A HB3  1 
ATOM   548  N N    . LYS A 1 37  ? 27.22217 41.37592 11.47272  1.000 52.29691  ? 37  LYS A N    1 
ATOM   549  C CA   . LYS A 1 37  ? 27.18256 41.42768 12.92575  1.000 56.69442  ? 37  LYS A CA   1 
ATOM   550  C C    . LYS A 1 37  ? 26.52978 40.19530 13.53543  1.000 49.06498  ? 37  LYS A C    1 
ATOM   551  O O    . LYS A 1 37  ? 26.58104 40.02343 14.75849  1.000 48.99326  ? 37  LYS A O    1 
ATOM   552  C CB   . LYS A 1 37  ? 26.41983 42.67483 13.38852  1.000 57.80745  ? 37  LYS A CB   1 
ATOM   553  C CG   . LYS A 1 37  ? 26.99342 43.99077 12.88264  1.000 70.31515  ? 37  LYS A CG   1 
ATOM   554  C CD   . LYS A 1 37  ? 28.05379 44.54575 13.82278  1.000 76.99318  ? 37  LYS A CD   1 
ATOM   555  C CE   . LYS A 1 37  ? 29.25760 45.06320 13.05040  1.000 67.73162  ? 37  LYS A CE   1 
ATOM   556  N NZ   . LYS A 1 37  ? 29.98693 43.95114 12.37635  1.000 61.87315  ? 37  LYS A NZ   1 
ATOM   557  H H    . LYS A 1 37  ? 26.55110 41.76285 11.09915  1.000 62.75629  ? 37  LYS A H    1 
ATOM   558  H HA   . LYS A 1 37  ? 28.09062 41.49041 13.26099  1.000 68.03330  ? 37  LYS A HA   1 
ATOM   559  H HB2  . LYS A 1 37  ? 25.50530 42.61286 13.07121  1.000 69.36894  ? 37  LYS A HB2  1 
ATOM   560  H HB3  . LYS A 1 37  ? 26.43342 42.70299 14.35802  1.000 69.36894  ? 37  LYS A HB3  1 
ATOM   561  H HG2  . LYS A 1 37  ? 27.40214 43.84887 12.01448  1.000 84.37818  ? 37  LYS A HG2  1 
ATOM   562  H HG3  . LYS A 1 37  ? 26.28002 44.64406 12.81068  1.000 84.37818  ? 37  LYS A HG3  1 
ATOM   563  H HD2  . LYS A 1 37  ? 27.67913 45.28027 14.33367  1.000 92.39182  ? 37  LYS A HD2  1 
ATOM   564  H HD3  . LYS A 1 37  ? 28.35302 43.84376 14.42160  1.000 92.39182  ? 37  LYS A HD3  1 
ATOM   565  H HE2  . LYS A 1 37  ? 28.95996 45.68938 12.37201  1.000 81.27794  ? 37  LYS A HE2  1 
ATOM   566  H HE3  . LYS A 1 37  ? 29.86823 45.50278 13.66261  1.000 81.27794  ? 37  LYS A HE3  1 
ATOM   567  H HZ1  . LYS A 1 37  ? 30.71943 44.26407 11.97934  1.000 74.24778  ? 37  LYS A HZ1  1 
ATOM   568  H HZ2  . LYS A 1 37  ? 30.22300 43.33550 12.97415  1.000 74.24778  ? 37  LYS A HZ2  1 
ATOM   569  H HZ3  . LYS A 1 37  ? 29.46507 43.57272 11.76271  1.000 74.24778  ? 37  LYS A HZ3  1 
ATOM   570  N N    . GLU A 1 38  ? 25.91283 39.34589 12.71942  1.000 48.35261  ? 38  GLU A N    1 
ATOM   571  C CA   . GLU A 1 38  ? 25.18689 38.18791 13.21911  1.000 42.33319  ? 38  GLU A CA   1 
ATOM   572  C C    . GLU A 1 38  ? 24.89770 37.25405 12.05615  1.000 40.63032  ? 38  GLU A C    1 
ATOM   573  O O    . GLU A 1 38  ? 24.87682 37.66594 10.89266  1.000 40.94206  ? 38  GLU A O    1 
ATOM   574  C CB   . GLU A 1 38  ? 23.88082 38.59484 13.92105  1.000 44.05440  ? 38  GLU A CB   1 
ATOM   575  C CG   . GLU A 1 38  ? 22.96134 39.51638 13.11567  1.000 54.17399  ? 38  GLU A CG   1 
ATOM   576  C CD   . GLU A 1 38  ? 22.18852 38.79506 12.02345  1.000 59.97747  ? 38  GLU A CD   1 
ATOM   577  O OE1  . GLU A 1 38  ? 21.90895 37.58716 12.17909  1.000 51.04332  ? 38  GLU A OE1  1 
ATOM   578  O OE2  . GLU A 1 38  ? 21.86114 39.44058 11.00480  1.000 65.94618  ? 38  GLU A OE2  1 
ATOM   579  H H    . GLU A 1 38  ? 25.90107 39.42104 11.86279  1.000 58.02313  ? 38  GLU A H    1 
ATOM   580  H HA   . GLU A 1 38  ? 25.74323 37.71461 13.85736  1.000 50.79983  ? 38  GLU A HA   1 
ATOM   581  H HB2  . GLU A 1 38  ? 23.37870 37.78968 14.12230  1.000 52.86528  ? 38  GLU A HB2  1 
ATOM   582  H HB3  . GLU A 1 38  ? 24.10730 39.05857 14.74237  1.000 52.86528  ? 38  GLU A HB3  1 
ATOM   583  H HG2  . GLU A 1 38  ? 22.31722 39.92067 13.71781  1.000 65.00879  ? 38  GLU A HG2  1 
ATOM   584  H HG3  . GLU A 1 38  ? 23.49890 40.20492 12.69397  1.000 65.00879  ? 38  GLU A HG3  1 
ATOM   585  N N    . PHE A 1 39  ? 24.68815 35.98534 12.39050  1.000 38.05809  ? 39  PHE A N    1 
ATOM   586  C CA   . PHE A 1 39  ? 24.19190 34.99086 11.45137  1.000 41.50341  ? 39  PHE A CA   1 
ATOM   587  C C    . PHE A 1 39  ? 23.02195 34.27706 12.11037  1.000 43.54957  ? 39  PHE A C    1 
ATOM   588  O O    . PHE A 1 39  ? 23.14565 33.79474 13.24142  1.000 42.42815  ? 39  PHE A O    1 
ATOM   589  C CB   . PHE A 1 39  ? 25.27188 33.97764 11.05820  1.000 43.30621  ? 39  PHE A CB   1 
ATOM   590  C CG   . PHE A 1 39  ? 26.45460 34.58211 10.35120  1.000 38.71348  ? 39  PHE A CG   1 
ATOM   591  C CD1  . PHE A 1 39  ? 26.29255 35.30065 9.17728   1.000 37.19512  ? 39  PHE A CD1  1 
ATOM   592  C CD2  . PHE A 1 39  ? 27.73421 34.40498 10.85104  1.000 37.92218  ? 39  PHE A CD2  1 
ATOM   593  C CE1  . PHE A 1 39  ? 27.38609 35.84649 8.52480   1.000 39.57972  ? 39  PHE A CE1  1 
ATOM   594  C CE2  . PHE A 1 39  ? 28.83129 34.94589 10.20245  1.000 40.93146  ? 39  PHE A CE2  1 
ATOM   595  C CZ   . PHE A 1 39  ? 28.65740 35.66708 9.03840   1.000 35.50210  ? 39  PHE A CZ   1 
ATOM   596  H H    . PHE A 1 39  ? 24.83057 35.66962 13.17767  1.000 45.66971  ? 39  PHE A H    1 
ATOM   597  H HA   . PHE A 1 39  ? 23.89501 35.42706 10.63744  1.000 49.80409  ? 39  PHE A HA   1 
ATOM   598  H HB2  . PHE A 1 39  ? 25.59913 33.54502 11.86235  1.000 51.96745  ? 39  PHE A HB2  1 
ATOM   599  H HB3  . PHE A 1 39  ? 24.87850 33.31951 10.46405  1.000 51.96745  ? 39  PHE A HB3  1 
ATOM   600  H HD1  . PHE A 1 39  ? 25.44042 35.41771 8.82362   1.000 44.63414  ? 39  PHE A HD1  1 
ATOM   601  H HD2  . PHE A 1 39  ? 27.85804 33.91631 11.63256  1.000 45.50661  ? 39  PHE A HD2  1 
ATOM   602  H HE1  . PHE A 1 39  ? 27.26517 36.33336 7.74170   1.000 47.49567  ? 39  PHE A HE1  1 
ATOM   603  H HE2  . PHE A 1 39  ? 29.68483 34.82341 10.55082  1.000 49.11775  ? 39  PHE A HE2  1 
ATOM   604  H HZ   . PHE A 1 39  ? 29.39291 36.03116 8.60093   1.000 42.60251  ? 39  PHE A HZ   1 
ATOM   605  N N    . PHE A 1 40  ? 21.88764 34.22429 11.41599  1.000 45.13689  ? 40  PHE A N    1 
ATOM   606  C CA   . PHE A 1 40  ? 20.70505 33.53097 11.91949  1.000 46.08006  ? 40  PHE A CA   1 
ATOM   607  C C    . PHE A 1 40  ? 20.25889 34.08576 13.26871  1.000 46.89863  ? 40  PHE A C    1 
ATOM   608  O O    . PHE A 1 40  ? 19.76535 33.34733 14.12455  1.000 46.68622  ? 40  PHE A O    1 
ATOM   609  C CB   . PHE A 1 40  ? 20.96390 32.02491 12.01434  1.000 40.15139  ? 40  PHE A CB   1 
ATOM   610  C CG   . PHE A 1 40  ? 21.58402 31.44701 10.77631  1.000 40.87311  ? 40  PHE A CG   1 
ATOM   611  C CD1  . PHE A 1 40  ? 20.94178 31.56070 9.55484   1.000 40.43920  ? 40  PHE A CD1  1 
ATOM   612  C CD2  . PHE A 1 40  ? 22.80839 30.80130 10.82767  1.000 36.80391  ? 40  PHE A CD2  1 
ATOM   613  C CE1  . PHE A 1 40  ? 21.50580 31.03853 8.40878   1.000 39.35061  ? 40  PHE A CE1  1 
ATOM   614  C CE2  . PHE A 1 40  ? 23.37803 30.27530 9.68248   1.000 33.41927  ? 40  PHE A CE2  1 
ATOM   615  C CZ   . PHE A 1 40  ? 22.72604 30.39376 8.47262   1.000 39.75324  ? 40  PHE A CZ   1 
ATOM   616  H H    . PHE A 1 40  ? 21.77751 34.58582 10.64348  1.000 54.16427  ? 40  PHE A H    1 
ATOM   617  H HA   . PHE A 1 40  ? 19.97362 33.67409 11.29866  1.000 55.29607  ? 40  PHE A HA   1 
ATOM   618  H HB2  . PHE A 1 40  ? 21.56692 31.85687 12.75531  1.000 48.18167  ? 40  PHE A HB2  1 
ATOM   619  H HB3  . PHE A 1 40  ? 20.11987 31.57092 12.16398  1.000 48.18167  ? 40  PHE A HB3  1 
ATOM   620  H HD1  . PHE A 1 40  ? 20.12043 31.99420 9.50626   1.000 48.52704  ? 40  PHE A HD1  1 
ATOM   621  H HD2  . PHE A 1 40  ? 23.25214 30.72061 11.64098  1.000 44.16469  ? 40  PHE A HD2  1 
ATOM   622  H HE1  . PHE A 1 40  ? 21.06487 31.12057 7.59407   1.000 47.22074  ? 40  PHE A HE1  1 
ATOM   623  H HE2  . PHE A 1 40  ? 24.19976 29.84219 9.72800   1.000 40.10313  ? 40  PHE A HE2  1 
ATOM   624  H HZ   . PHE A 1 40  ? 23.10713 30.04029 7.70144   1.000 47.70389  ? 40  PHE A HZ   1 
ATOM   625  N N    . GLY A 1 41  ? 20.43278 35.39165 13.46700  1.000 46.14797  ? 41  GLY A N    1 
ATOM   626  C CA   . GLY A 1 41  ? 20.00819 36.04878 14.68338  1.000 49.00763  ? 41  GLY A CA   1 
ATOM   627  C C    . GLY A 1 41  ? 20.96524 35.95350 15.85017  1.000 52.02149  ? 41  GLY A C    1 
ATOM   628  O O    . GLY A 1 41  ? 20.69326 36.54787 16.90097  1.000 50.87617  ? 41  GLY A O    1 
ATOM   629  H H    . GLY A 1 41  ? 20.80111 35.92085 12.89790  1.000 55.37757  ? 41  GLY A H    1 
ATOM   630  H HA2  . GLY A 1 41  ? 19.87316 36.99020 14.49264  1.000 58.80915  ? 41  GLY A HA2  1 
ATOM   631  H HA3  . GLY A 1 41  ? 19.16540 35.65946 14.96450  1.000 58.80915  ? 41  GLY A HA3  1 
ATOM   632  N N    . VAL A 1 42  ? 22.07467 35.23645 15.70887  1.000 46.00144  ? 42  VAL A N    1 
ATOM   633  C CA   . VAL A 1 42  ? 23.03134 35.03809 16.79149  1.000 46.38049  ? 42  VAL A CA   1 
ATOM   634  C C    . VAL A 1 42  ? 24.16560 36.04638 16.61237  1.000 45.75550  ? 42  VAL A C    1 
ATOM   635  O O    . VAL A 1 42  ? 24.80532 36.05064 15.55095  1.000 42.95322  ? 42  VAL A O    1 
ATOM   636  C CB   . VAL A 1 42  ? 23.57933 33.60307 16.80653  1.000 50.01268  ? 42  VAL A CB   1 
ATOM   637  C CG1  . VAL A 1 42  ? 24.51952 33.41768 17.99067  1.000 43.95582  ? 42  VAL A CG1  1 
ATOM   638  C CG2  . VAL A 1 42  ? 22.43840 32.59368 16.84808  1.000 45.46375  ? 42  VAL A CG2  1 
ATOM   639  H H    . VAL A 1 42  ? 22.30028 34.84543 14.97689  1.000 55.20172  ? 42  VAL A H    1 
ATOM   640  H HA   . VAL A 1 42  ? 22.59289 35.21083 17.63933  1.000 55.65659  ? 42  VAL A HA   1 
ATOM   641  H HB   . VAL A 1 42  ? 24.08189 33.44280 15.99249  1.000 60.01522  ? 42  VAL A HB   1 
ATOM   642  H HG11 . VAL A 1 42  ? 24.17492 33.91555 18.74848  1.000 52.74699  ? 42  VAL A HG11 1 
ATOM   643  H HG12 . VAL A 1 42  ? 24.56916 32.47406 18.20979  1.000 52.74699  ? 42  VAL A HG12 1 
ATOM   644  H HG13 . VAL A 1 42  ? 25.39922 33.74814 17.75020  1.000 52.74699  ? 42  VAL A HG13 1 
ATOM   645  H HG21 . VAL A 1 42  ? 21.59666 33.07108 16.91492  1.000 54.55650  ? 42  VAL A HG21 1 
ATOM   646  H HG22 . VAL A 1 42  ? 22.45500 32.06467 16.03520  1.000 54.55650  ? 42  VAL A HG22 1 
ATOM   647  H HG23 . VAL A 1 42  ? 22.55423 32.01775 17.61996  1.000 54.55650  ? 42  VAL A HG23 1 
ATOM   648  N N    . PRO A 1 43  ? 24.44254 36.89866 17.60041  1.000 44.77093  ? 43  PRO A N    1 
ATOM   649  C CA   . PRO A 1 43  ? 25.58897 37.80967 17.47131  1.000 45.90218  ? 43  PRO A CA   1 
ATOM   650  C C    . PRO A 1 43  ? 26.87520 37.04690 17.18792  1.000 42.58191  ? 43  PRO A C    1 
ATOM   651  O O    . PRO A 1 43  ? 27.16766 36.02318 17.81025  1.000 48.34489  ? 43  PRO A O    1 
ATOM   652  C CB   . PRO A 1 43  ? 25.63278 38.52225 18.82858  1.000 50.74795  ? 43  PRO A CB   1 
ATOM   653  C CG   . PRO A 1 43  ? 24.22106 38.47899 19.31526  1.000 50.21612  ? 43  PRO A CG   1 
ATOM   654  C CD   . PRO A 1 43  ? 23.66412 37.16276 18.82602  1.000 49.28324  ? 43  PRO A CD   1 
ATOM   655  H HA   . PRO A 1 43  ? 25.43613 38.45970 16.76775  1.000 55.08261  ? 43  PRO A HA   1 
ATOM   656  H HB2  . PRO A 1 43  ? 26.22566 38.04960 19.43357  1.000 60.89754  ? 43  PRO A HB2  1 
ATOM   657  H HB3  . PRO A 1 43  ? 25.93532 39.43679 18.71467  1.000 60.89754  ? 43  PRO A HB3  1 
ATOM   658  H HG2  . PRO A 1 43  ? 24.20635 38.52058 20.28425  1.000 60.25934  ? 43  PRO A HG2  1 
ATOM   659  H HG3  . PRO A 1 43  ? 23.72265 39.22356 18.94363  1.000 60.25934  ? 43  PRO A HG3  1 
ATOM   660  H HD2  . PRO A 1 43  ? 23.80578 36.46275 19.48239  1.000 59.13989  ? 43  PRO A HD2  1 
ATOM   661  H HD3  . PRO A 1 43  ? 22.71867 37.24178 18.62407  1.000 59.13989  ? 43  PRO A HD3  1 
ATOM   662  N N    . ILE A 1 44  ? 27.64999 37.57116 16.23389  1.000 43.44299  ? 44  ILE A N    1 
ATOM   663  C CA   . ILE A 1 44  ? 28.82168 36.86323 15.72346  1.000 43.85369  ? 44  ILE A CA   1 
ATOM   664  C C    . ILE A 1 44  ? 29.80235 36.51352 16.83723  1.000 45.27651  ? 44  ILE A C    1 
ATOM   665  O O    . ILE A 1 44  ? 30.51001 35.50197 16.74921  1.000 43.00415  ? 44  ILE A O    1 
ATOM   666  C CB   . ILE A 1 44  ? 29.48525 37.71013 14.61101  1.000 51.41150  ? 44  ILE A CB   1 
ATOM   667  C CG1  . ILE A 1 44  ? 30.78136 37.06040 14.12113  1.000 50.86372  ? 44  ILE A CG1  1 
ATOM   668  C CG2  . ILE A 1 44  ? 29.73887 39.14247 15.08682  1.000 54.56682  ? 44  ILE A CG2  1 
ATOM   669  C CD1  . ILE A 1 44  ? 30.56479 35.74987 13.40142  1.000 53.20290  ? 44  ILE A CD1  1 
ATOM   670  H H    . ILE A 1 44  ? 27.51751 38.33693 15.86560  1.000 52.13159  ? 44  ILE A H    1 
ATOM   671  H HA   . ILE A 1 44  ? 28.53119 36.02064 15.34062  1.000 52.62443  ? 44  ILE A HA   1 
ATOM   672  H HB   . ILE A 1 44  ? 28.86785 37.74543 13.86370  1.000 61.69380  ? 44  ILE A HB   1 
ATOM   673  H HG12 . ILE A 1 44  ? 31.22257 37.66738 13.50648  1.000 61.03646  ? 44  ILE A HG12 1 
ATOM   674  H HG13 . ILE A 1 44  ? 31.35331 36.88847 14.88547  1.000 61.03646  ? 44  ILE A HG13 1 
ATOM   675  H HG21 . ILE A 1 44  ? 30.16043 39.64309 14.37088  1.000 65.48019  ? 44  ILE A HG21 1 
ATOM   676  H HG22 . ILE A 1 44  ? 28.89153 39.55174 15.32223  1.000 65.48019  ? 44  ILE A HG22 1 
ATOM   677  H HG23 . ILE A 1 44  ? 30.32165 39.11925 15.86189  1.000 65.48019  ? 44  ILE A HG23 1 
ATOM   678  H HD11 . ILE A 1 44  ? 31.42435 35.39599 13.12425  1.000 63.84348  ? 44  ILE A HD11 1 
ATOM   679  H HD12 . ILE A 1 44  ? 30.12933 35.12685 14.00402  1.000 63.84348  ? 44  ILE A HD12 1 
ATOM   680  H HD13 . ILE A 1 44  ? 30.00487 35.90493 12.62467  1.000 63.84348  ? 44  ILE A HD13 1 
ATOM   681  N N    . LYS A 1 45  ? 29.86637 37.32313 17.89774  1.000 44.00355  ? 45  LYS A N    1 
ATOM   682  C CA   . LYS A 1 45  ? 30.81180 37.03649 18.97492  1.000 47.18393  ? 45  LYS A CA   1 
ATOM   683  C C    . LYS A 1 45  ? 30.45108 35.75221 19.71456  1.000 47.08549  ? 45  LYS A C    1 
ATOM   684  O O    . LYS A 1 45  ? 31.33114 35.10561 20.29481  1.000 41.12694  ? 45  LYS A O    1 
ATOM   685  C CB   . LYS A 1 45  ? 30.87046 38.21282 19.95252  1.000 54.15163  ? 45  LYS A CB   1 
ATOM   686  C CG   . LYS A 1 45  ? 32.14763 38.29624 20.79823  1.000 64.53162  ? 45  LYS A CG   1 
ATOM   687  C CD   . LYS A 1 45  ? 33.39377 38.50555 19.93925  1.000 66.08355  ? 45  LYS A CD   1 
ATOM   688  C CE   . LYS A 1 45  ? 34.58615 38.99133 20.76199  1.000 80.43957  ? 45  LYS A CE   1 
ATOM   689  N NZ   . LYS A 1 45  ? 34.91400 38.10674 21.91530  1.000 82.52569  ? 45  LYS A NZ   1 
ATOM   690  H H    . LYS A 1 45  ? 29.38544 38.02653 18.01403  1.000 52.80426  ? 45  LYS A H    1 
ATOM   691  H HA   . LYS A 1 45  ? 31.69478 36.92272 18.58981  1.000 56.62071  ? 45  LYS A HA   1 
ATOM   692  H HB2  . LYS A 1 45  ? 30.80469 39.03659 19.44462  1.000 64.98195  ? 45  LYS A HB2  1 
ATOM   693  H HB3  . LYS A 1 45  ? 30.12158 38.13981 20.56469  1.000 64.98195  ? 45  LYS A HB3  1 
ATOM   694  H HG2  . LYS A 1 45  ? 32.07509 39.04333 21.41264  1.000 77.43795  ? 45  LYS A HG2  1 
ATOM   695  H HG3  . LYS A 1 45  ? 32.25708 37.46916 21.29307  1.000 77.43795  ? 45  LYS A HG3  1 
ATOM   696  H HD2  . LYS A 1 45  ? 33.63765 37.66492 19.52121  1.000 79.30026  ? 45  LYS A HD2  1 
ATOM   697  H HD3  . LYS A 1 45  ? 33.20436 39.17134 19.25972  1.000 79.30026  ? 45  LYS A HD3  1 
ATOM   698  H HE2  . LYS A 1 45  ? 35.36712 39.03159 20.18808  1.000 96.52748  ? 45  LYS A HE2  1 
ATOM   699  H HE3  . LYS A 1 45  ? 34.38626 39.87340 21.11258  1.000 96.52748  ? 45  LYS A HE3  1 
ATOM   700  H HZ1  . LYS A 1 45  ? 35.61366 38.43184 22.35903  1.000 99.03083  ? 45  LYS A HZ1  1 
ATOM   701  H HZ2  . LYS A 1 45  ? 34.21858 38.05756 22.46853  1.000 99.03083  ? 45  LYS A HZ2  1 
ATOM   702  H HZ3  . LYS A 1 45  ? 35.11071 37.28867 21.62519  1.000 99.03083  ? 45  LYS A HZ3  1 
ATOM   703  N N    . GLN A 1 46  ? 29.17381 35.36778 19.71126  1.000 44.42507  ? 46  GLN A N    1 
ATOM   704  C CA   . GLN A 1 46  ? 28.75706 34.13081 20.35890  1.000 42.12730  ? 46  GLN A CA   1 
ATOM   705  C C    . GLN A 1 46  ? 28.97189 32.90396 19.48263  1.000 39.95352  ? 46  GLN A C    1 
ATOM   706  O O    . GLN A 1 46  ? 28.85772 31.77919 19.98181  1.000 41.57252  ? 46  GLN A O    1 
ATOM   707  C CB   . GLN A 1 46  ? 27.28202 34.21674 20.75999  1.000 44.16827  ? 46  GLN A CB   1 
ATOM   708  C CG   . GLN A 1 46  ? 26.93147 35.47102 21.54198  1.000 46.26796  ? 46  GLN A CG   1 
ATOM   709  C CD   . GLN A 1 46  ? 25.51363 35.45276 22.07970  1.000 53.92057  ? 46  GLN A CD   1 
ATOM   710  O OE1  . GLN A 1 46  ? 24.99093 34.40276 22.45366  1.000 53.41790  ? 46  GLN A OE1  1 
ATOM   711  N NE2  . GLN A 1 46  ? 24.88285 36.62054 22.12023  1.000 53.77918  ? 46  GLN A NE2  1 
ATOM   712  H H    . GLN A 1 46  ? 28.53363 35.80672 19.34099  1.000 53.31009  ? 46  GLN A H    1 
ATOM   713  H HA   . GLN A 1 46  ? 29.27942 34.01544 21.16805  1.000 50.55276  ? 46  GLN A HA   1 
ATOM   714  H HB2  . GLN A 1 46  ? 26.73943 34.20791 19.95599  1.000 53.00193  ? 46  GLN A HB2  1 
ATOM   715  H HB3  . GLN A 1 46  ? 27.06495 33.45151 21.31515  1.000 53.00193  ? 46  GLN A HB3  1 
ATOM   716  H HG2  . GLN A 1 46  ? 27.53663 35.55266 22.29565  1.000 55.52155  ? 46  GLN A HG2  1 
ATOM   717  H HG3  . GLN A 1 46  ? 27.02106 36.24154 20.95960  1.000 55.52155  ? 46  GLN A HG3  1 
ATOM   718  H HE21 . GLN A 1 46  ? 25.28039 37.33360 21.84984  1.000 64.53502  ? 46  GLN A HE21 1 
ATOM   719  H HE22 . GLN A 1 46  ? 24.07679 36.66379 22.41686  1.000 64.53502  ? 46  GLN A HE22 1 
ATOM   720  N N    . ILE A 1 47  ? 29.28024 33.08850 18.20359  1.000 41.11559  ? 47  ILE A N    1 
ATOM   721  C CA   . ILE A 1 47  ? 29.49268 31.97674 17.28463  1.000 39.98206  ? 47  ILE A CA   1 
ATOM   722  C C    . ILE A 1 47  ? 30.97382 31.62895 17.27651  1.000 42.48978  ? 47  ILE A C    1 
ATOM   723  O O    . ILE A 1 47  ? 31.83040 32.51427 17.16414  1.000 41.19866  ? 47  ILE A O    1 
ATOM   724  C CB   . ILE A 1 47  ? 29.00348 32.32964 15.87059  1.000 41.61493  ? 47  ILE A CB   1 
ATOM   725  C CG1  . ILE A 1 47  ? 27.51409 32.67888 15.89141  1.000 45.67610  ? 47  ILE A CG1  1 
ATOM   726  C CG2  . ILE A 1 47  ? 29.25375 31.16964 14.92002  1.000 40.39431  ? 47  ILE A CG2  1 
ATOM   727  C CD1  . ILE A 1 47  ? 27.03567 33.40137 14.64796  1.000 46.51097  ? 47  ILE A CD1  1 
ATOM   728  H H    . ILE A 1 47  ? 29.37357 33.86146 17.83831  1.000 49.33871  ? 47  ILE A H    1 
ATOM   729  H HA   . ILE A 1 47  ? 28.99552 31.20415 17.59582  1.000 47.97847  ? 47  ILE A HA   1 
ATOM   730  H HB   . ILE A 1 47  ? 29.50055 33.10322 15.56174  1.000 49.93792  ? 47  ILE A HB   1 
ATOM   731  H HG12 . ILE A 1 47  ? 27.00296 31.85838 15.97149  1.000 54.81132  ? 47  ILE A HG12 1 
ATOM   732  H HG13 . ILE A 1 47  ? 27.33975 33.25400 16.65282  1.000 54.81132  ? 47  ILE A HG13 1 
ATOM   733  H HG21 . ILE A 1 47  ? 30.20977 31.06664 14.79228  1.000 48.47317  ? 47  ILE A HG21 1 
ATOM   734  H HG22 . ILE A 1 47  ? 28.88233 30.36034 15.30470  1.000 48.47317  ? 47  ILE A HG22 1 
ATOM   735  H HG23 . ILE A 1 47  ? 28.82508 31.35915 14.07076  1.000 48.47317  ? 47  ILE A HG23 1 
ATOM   736  H HD11 . ILE A 1 47  ? 27.06492 32.78921 13.89610  1.000 55.81316  ? 47  ILE A HD11 1 
ATOM   737  H HD12 . ILE A 1 47  ? 26.12616 33.70694 14.79053  1.000 55.81316  ? 47  ILE A HD12 1 
ATOM   738  H HD13 . ILE A 1 47  ? 27.61686 34.15959 14.47998  1.000 55.81316  ? 47  ILE A HD13 1 
ATOM   739  N N    . GLN A 1 48  ? 31.27748 30.33975 17.39991  1.000 43.51639  ? 48  GLN A N    1 
ATOM   740  C CA   . GLN A 1 48  ? 32.65348 29.85105 17.34446  1.000 45.02626  ? 48  GLN A CA   1 
ATOM   741  C C    . GLN A 1 48  ? 32.96153 29.49631 15.89622  1.000 42.12662  ? 48  GLN A C    1 
ATOM   742  O O    . GLN A 1 48  ? 32.52220 28.45942 15.39175  1.000 39.85262  ? 48  GLN A O    1 
ATOM   743  C CB   . GLN A 1 48  ? 32.84122 28.65644 18.27104  1.000 49.21742  ? 48  GLN A CB   1 
ATOM   744  C CG   . GLN A 1 48  ? 32.90071 29.02036 19.74349  1.000 66.80043  ? 48  GLN A CG   1 
ATOM   745  C CD   . GLN A 1 48  ? 33.29602 27.84446 20.61362  1.000 89.61098  ? 48  GLN A CD   1 
ATOM   746  O OE1  . GLN A 1 48  ? 32.55765 26.86643 20.73012  1.000 89.58984  ? 48  GLN A OE1  1 
ATOM   747  N NE2  . GLN A 1 48  ? 34.47234 27.93004 21.22382  1.000 102.99244 ? 48  GLN A NE2  1 
ATOM   748  H H    . GLN A 1 48  ? 30.69500 29.71826 17.51849  1.000 52.21967  ? 48  GLN A H    1 
ATOM   749  H HA   . GLN A 1 48  ? 33.26153 30.55081 17.62997  1.000 54.03152  ? 48  GLN A HA   1 
ATOM   750  H HB2  . GLN A 1 48  ? 32.09658 28.04721 18.14750  1.000 59.06090  ? 48  GLN A HB2  1 
ATOM   751  H HB3  . GLN A 1 48  ? 33.67351 28.21369 18.04264  1.000 59.06090  ? 48  GLN A HB3  1 
ATOM   752  H HG2  . GLN A 1 48  ? 33.55690 29.72334 19.87048  1.000 80.16052  ? 48  GLN A HG2  1 
ATOM   753  H HG3  . GLN A 1 48  ? 32.02628 29.32701 20.03027  1.000 80.16052  ? 48  GLN A HG3  1 
ATOM   754  H HE21 . GLN A 1 48  ? 34.96408 28.62697 21.11389  1.000 123.59093 ? 48  GLN A HE21 1 
ATOM   755  H HE22 . GLN A 1 48  ? 34.74241 27.28854 21.72892  1.000 123.59093 ? 48  GLN A HE22 1 
ATOM   756  N N    . VAL A 1 49  ? 33.71088 30.36563 15.22163  1.000 36.08416  ? 49  VAL A N    1 
ATOM   757  C CA   . VAL A 1 49  ? 34.04313 30.18873 13.81410  1.000 36.05459  ? 49  VAL A CA   1 
ATOM   758  C C    . VAL A 1 49  ? 35.42490 29.55807 13.71212  1.000 39.59711  ? 49  VAL A C    1 
ATOM   759  O O    . VAL A 1 49  ? 36.39979 30.07293 14.27823  1.000 34.76235  ? 49  VAL A O    1 
ATOM   760  C CB   . VAL A 1 49  ? 33.99608 31.52436 13.05162  1.000 35.43407  ? 49  VAL A CB   1 
ATOM   761  C CG1  . VAL A 1 49  ? 34.22015 31.28584 11.56525  1.000 38.89239  ? 49  VAL A CG1  1 
ATOM   762  C CG2  . VAL A 1 49  ? 32.66933 32.23437 13.28188  1.000 37.89618  ? 49  VAL A CG2  1 
ATOM   763  H H    . VAL A 1 49  ? 34.04401 31.07938 15.56685  1.000 43.30100  ? 49  VAL A H    1 
ATOM   764  H HA   . VAL A 1 49  ? 33.39882 29.58436 13.41348  1.000 43.26551  ? 49  VAL A HA   1 
ATOM   765  H HB   . VAL A 1 49  ? 34.70286 32.09942 13.38428  1.000 42.52089  ? 49  VAL A HB   1 
ATOM   766  H HG11 . VAL A 1 49  ? 34.06181 32.11370 11.08517  1.000 46.67087  ? 49  VAL A HG11 1 
ATOM   767  H HG12 . VAL A 1 49  ? 35.13439 30.99280 11.42673  1.000 46.67087  ? 49  VAL A HG12 1 
ATOM   768  H HG13 . VAL A 1 49  ? 33.60372 30.60255 11.25860  1.000 46.67087  ? 49  VAL A HG13 1 
ATOM   769  H HG21 . VAL A 1 49  ? 32.07194 31.63956 13.76170  1.000 45.47541  ? 49  VAL A HG21 1 
ATOM   770  H HG22 . VAL A 1 49  ? 32.82689 33.03662 13.80386  1.000 45.47541  ? 49  VAL A HG22 1 
ATOM   771  H HG23 . VAL A 1 49  ? 32.28345 32.46880 12.42337  1.000 45.47541  ? 49  VAL A HG23 1 
ATOM   772  N N    A HIS A 1 50  ? 35.50323 28.43506 13.00625  0.512 37.48314  ? 50  HIS A N    1 
ATOM   773  N N    B HIS A 1 50  ? 35.50856 28.44299 12.99501  0.488 38.09348  ? 50  HIS A N    1 
ATOM   774  C CA   A HIS A 1 50  ? 36.75990 27.76577 12.70586  0.512 38.80402  ? 50  HIS A CA   1 
ATOM   775  C CA   B HIS A 1 50  ? 36.77207 27.78122 12.71149  0.488 38.83594  ? 50  HIS A CA   1 
ATOM   776  C C    A HIS A 1 50  ? 37.01738 27.84829 11.20728  0.512 38.41796  ? 50  HIS A C    1 
ATOM   777  C C    B HIS A 1 50  ? 37.01846 27.80500 11.21044  0.488 38.59188  ? 50  HIS A C    1 
ATOM   778  O O    A HIS A 1 50  ? 36.08248 27.96244 10.40505  0.512 38.01957  ? 50  HIS A O    1 
ATOM   779  O O    B HIS A 1 50  ? 36.07617 27.82891 10.40866  0.488 38.20339  ? 50  HIS A O    1 
ATOM   780  C CB   A HIS A 1 50  ? 36.74192 26.30307 13.15771  0.512 40.14041  ? 50  HIS A CB   1 
ATOM   781  C CB   B HIS A 1 50  ? 36.78210 26.33869 13.22951  0.488 38.72457  ? 50  HIS A CB   1 
ATOM   782  C CG   A HIS A 1 50  ? 38.03671 25.58286 12.92540  0.512 41.21807  ? 50  HIS A CG   1 
ATOM   783  C CG   B HIS A 1 50  ? 36.70079 26.23233 14.72089  0.488 38.48587  ? 50  HIS A CG   1 
ATOM   784  N ND1  A HIS A 1 50  ? 39.20500 25.92030 13.57568  0.512 40.92558  ? 50  HIS A ND1  1 
ATOM   785  N ND1  B HIS A 1 50  ? 35.56740 26.56896 15.42858  0.488 43.84929  ? 50  HIS A ND1  1 
ATOM   786  C CD2  A HIS A 1 50  ? 38.34761 24.54819 12.10847  0.512 41.34453  ? 50  HIS A CD2  1 
ATOM   787  C CD2  B HIS A 1 50  ? 37.61123 25.82910 15.63875  0.488 41.37718  ? 50  HIS A CD2  1 
ATOM   788  C CE1  A HIS A 1 50  ? 40.17813 25.12306 13.17188  0.512 38.68536  ? 50  HIS A CE1  1 
ATOM   789  C CE1  B HIS A 1 50  ? 35.78174 26.37606 16.71765  0.488 44.70849  ? 50  HIS A CE1  1 
ATOM   790  N NE2  A HIS A 1 50  ? 39.68426 24.28130 12.28197  0.512 38.12832  ? 50  HIS A NE2  1 
ATOM   791  N NE2  B HIS A 1 50  ? 37.01412 25.92697 16.87199  0.488 36.60998  ? 50  HIS A NE2  1 
ATOM   792  H H    A HIS A 1 50  ? 34.81817 28.02978 12.68059  0.512 44.97977  ? 50  HIS A H    1 
ATOM   793  H H    B HIS A 1 50  ? 34.82836 28.04213 12.65409  0.488 45.71218  ? 50  HIS A H    1 
ATOM   794  H HA   A HIS A 1 50  ? 37.48793 28.20145 13.17602  0.512 46.56482  ? 50  HIS A HA   1 
ATOM   795  H HA   B HIS A 1 50  ? 37.49840 28.25053 13.15091  0.488 46.60313  ? 50  HIS A HA   1 
ATOM   796  H HB2  A HIS A 1 50  ? 36.55277 26.27272 14.10861  0.512 48.16849  ? 50  HIS A HB2  1 
ATOM   797  H HB2  B HIS A 1 50  ? 36.01979 25.86838 12.85724  0.488 46.46948  ? 50  HIS A HB2  1 
ATOM   798  H HB3  A HIS A 1 50  ? 36.04970 25.83344 12.66661  0.512 48.16849  ? 50  HIS A HB3  1 
ATOM   799  H HB3  B HIS A 1 50  ? 37.60583 25.91156 12.94679  0.488 46.46948  ? 50  HIS A HB3  1 
ATOM   800  H HD2  A HIS A 1 50  ? 37.76528 24.10188 11.53698  0.512 49.61344  ? 50  HIS A HD2  1 
ATOM   801  H HD2  B HIS A 1 50  ? 38.47823 25.54010 15.46645  0.488 49.65261  ? 50  HIS A HD2  1 
ATOM   802  H HE1  A HIS A 1 50  ? 41.06051 25.15001 13.46443  0.512 46.42243  ? 50  HIS A HE1  1 
ATOM   803  H HE1  B HIS A 1 50  ? 35.16920 26.53021 17.40024  0.488 53.65018  ? 50  HIS A HE1  1 
ATOM   804  H HE2  A HIS A 1 50  ? 40.12753 23.66578 11.87671  0.512 45.75398  ? 50  HIS A HE2  1 
ATOM   805  H HE2  B HIS A 1 50  ? 37.38303 25.72804 17.62294  0.488 43.93197  ? 50  HIS A HE2  1 
ATOM   806  N N    . LYS A 1 51  ? 38.29412 27.79214 10.83332  1.000 38.15871  ? 51  LYS A N    1 
ATOM   807  C CA   . LYS A 1 51  ? 38.67309 27.93590 9.44063   1.000 36.59789  ? 51  LYS A CA   1 
ATOM   808  C C    . LYS A 1 51  ? 39.87355 27.05601 9.15602   1.000 36.51352  ? 51  LYS A C    1 
ATOM   809  O O    . LYS A 1 51  ? 40.89704 27.15792 9.83681   1.000 34.41562  ? 51  LYS A O    1 
ATOM   810  C CB   . LYS A 1 51  ? 38.98123 29.39789 9.11187   1.000 33.06316  ? 51  LYS A CB   1 
ATOM   811  C CG   . LYS A 1 51  ? 38.62724 29.79206 7.69856   1.000 48.29541  ? 51  LYS A CG   1 
ATOM   812  C CD   . LYS A 1 51  ? 38.54221 31.30340 7.54753   1.000 59.16939  ? 51  LYS A CD   1 
ATOM   813  C CE   . LYS A 1 51  ? 37.39921 31.89991 8.36378   1.000 50.64758  ? 51  LYS A CE   1 
ATOM   814  N NZ   . LYS A 1 51  ? 36.15385 31.08500 8.29303   1.000 50.87518  ? 51  LYS A NZ   1 
ATOM   815  H H    . LYS A 1 51  ? 38.95629 27.67173 11.36869  1.000 45.79045  ? 51  LYS A H    1 
ATOM   816  H HA   . LYS A 1 51  ? 37.94839 27.63896 8.86833   1.000 43.91746  ? 51  LYS A HA   1 
ATOM   817  H HB2  . LYS A 1 51  ? 38.47471 29.96597 9.71323   1.000 39.67580  ? 51  LYS A HB2  1 
ATOM   818  H HB3  . LYS A 1 51  ? 39.93145 29.55086 9.23260   1.000 39.67580  ? 51  LYS A HB3  1 
ATOM   819  H HG2  . LYS A 1 51  ? 39.30927 29.46276 7.09252   1.000 57.95449  ? 51  LYS A HG2  1 
ATOM   820  H HG3  . LYS A 1 51  ? 37.76528 29.41316 7.46540   1.000 57.95449  ? 51  LYS A HG3  1 
ATOM   821  H HD2  . LYS A 1 51  ? 39.37201 31.70158 7.85378   1.000 71.00327  ? 51  LYS A HD2  1 
ATOM   822  H HD3  . LYS A 1 51  ? 38.39357 31.52268 6.61440   1.000 71.00327  ? 51  LYS A HD3  1 
ATOM   823  H HE2  . LYS A 1 51  ? 37.66942 31.95420 9.29380   1.000 60.77710  ? 51  LYS A HE2  1 
ATOM   824  H HE3  . LYS A 1 51  ? 37.19723 32.78599 8.02472   1.000 60.77710  ? 51  LYS A HE3  1 
ATOM   825  H HZ1  . LYS A 1 51  ? 35.90959 30.97542 7.44425   1.000 61.05021  ? 51  LYS A HZ1  1 
ATOM   826  H HZ2  . LYS A 1 51  ? 35.49682 31.49441 8.73212   1.000 61.05021  ? 51  LYS A HZ2  1 
ATOM   827  H HZ3  . LYS A 1 51  ? 36.29186 30.28572 8.65937   1.000 61.05021  ? 51  LYS A HZ3  1 
ATOM   828  N N    . SER A 1 52  ? 39.73518 26.19473 8.15048   1.000 35.69628  ? 52  SER A N    1 
ATOM   829  C CA   . SER A 1 52  ? 40.80426 25.30702 7.68953   1.000 40.13384  ? 52  SER A CA   1 
ATOM   830  C C    . SER A 1 52  ? 40.88802 25.50881 6.17876   1.000 31.75013  ? 52  SER A C    1 
ATOM   831  O O    . SER A 1 52  ? 40.28033 24.76412 5.40673   1.000 30.70643  ? 52  SER A O    1 
ATOM   832  C CB   . SER A 1 52  ? 40.52495 23.85635 8.06512   1.000 35.54355  ? 52  SER A CB   1 
ATOM   833  O OG   . SER A 1 52  ? 41.66351 23.04459 7.84483   1.000 43.62081  ? 52  SER A OG   1 
ATOM   834  H H    . SER A 1 52  ? 39.00620 26.10249 7.70362   1.000 42.83553  ? 52  SER A H    1 
ATOM   835  H HA   . SER A 1 52  ? 41.64787 25.55327 8.10012   1.000 48.16061  ? 52  SER A HA   1 
ATOM   836  H HB2  . SER A 1 52  ? 40.28578 23.81485 9.00425   1.000 42.65226  ? 52  SER A HB2  1 
ATOM   837  H HB3  . SER A 1 52  ? 39.79281 23.52584 7.52139   1.000 42.65226  ? 52  SER A HB3  1 
ATOM   838  H HG   . SER A 1 52  ? 41.53511 22.27743 8.16197   1.000 52.34497  ? 52  SER A HG   1 
ATOM   839  N N    . GLY A 1 53  ? 41.63336 26.53140 5.76440   1.000 33.60384  ? 53  GLY A N    1 
ATOM   840  C CA   . GLY A 1 53  ? 41.68244 26.90858 4.36782   1.000 34.46303  ? 53  GLY A CA   1 
ATOM   841  C C    . GLY A 1 53  ? 40.34339 27.41618 3.87532   1.000 37.46749  ? 53  GLY A C    1 
ATOM   842  O O    . GLY A 1 53  ? 39.91797 28.51781 4.23232   1.000 38.61190  ? 53  GLY A O    1 
ATOM   843  H H    . GLY A 1 53  ? 42.11899 27.02014 6.27909   1.000 40.32461  ? 53  GLY A H    1 
ATOM   844  H HA2  . GLY A 1 53  ? 42.34194 27.60926 4.24526   1.000 41.35564  ? 53  GLY A HA2  1 
ATOM   845  H HA3  . GLY A 1 53  ? 41.93600 26.13938 3.83402   1.000 41.35564  ? 53  GLY A HA3  1 
ATOM   846  N N    . GLU A 1 54  ? 39.66330 26.61138 3.06312   1.000 33.41756  ? 54  GLU A N    1 
ATOM   847  C CA   . GLU A 1 54  ? 38.37019 26.97155 2.50009   1.000 34.74449  ? 54  GLU A CA   1 
ATOM   848  C C    . GLU A 1 54  ? 37.20374 26.34311 3.24827   1.000 32.01382  ? 54  GLU A C    1 
ATOM   849  O O    . GLU A 1 54  ? 36.04780 26.61732 2.91106   1.000 32.95169  ? 54  GLU A O    1 
ATOM   850  C CB   . GLU A 1 54  ? 38.31947 26.56989 1.02410   1.000 34.77346  ? 54  GLU A CB   1 
ATOM   851  C CG   . GLU A 1 54  ? 39.16568 27.45783 0.13060   1.000 40.21373  ? 54  GLU A CG   1 
ATOM   852  C CD   . GLU A 1 54  ? 38.66039 28.88637 0.10606   1.000 45.88104  ? 54  GLU A CD   1 
ATOM   853  O OE1  . GLU A 1 54  ? 37.43259 29.08432 -0.03030  1.000 42.40486  ? 54  GLU A OE1  1 
ATOM   854  O OE2  . GLU A 1 54  ? 39.48606 29.81199 0.24007   1.000 50.44971  ? 54  GLU A OE2  1 
ATOM   855  H H    . GLU A 1 54  ? 39.93852 25.83398 2.81921   1.000 40.10107  ? 54  GLU A H    1 
ATOM   856  H HA   . GLU A 1 54  ? 38.26278 27.93423 2.55121   1.000 41.69339  ? 54  GLU A HA   1 
ATOM   857  H HB2  . GLU A 1 54  ? 38.64535 25.66060 0.93526   1.000 41.72815  ? 54  GLU A HB2  1 
ATOM   858  H HB3  . GLU A 1 54  ? 37.40149 26.62495 0.71558   1.000 41.72815  ? 54  GLU A HB3  1 
ATOM   859  H HG2  . GLU A 1 54  ? 40.07802 27.46476 0.45998   1.000 48.25647  ? 54  GLU A HG2  1 
ATOM   860  H HG3  . GLU A 1 54  ? 39.14275 27.11272 -0.77564  1.000 48.25647  ? 54  GLU A HG3  1 
ATOM   861  N N    . PHE A 1 55  ? 37.47733 25.51302 4.25016   1.000 30.50147  ? 55  PHE A N    1 
ATOM   862  C CA   . PHE A 1 55  ? 36.44157 24.92397 5.09116   1.000 33.34424  ? 55  PHE A CA   1 
ATOM   863  C C    . PHE A 1 55  ? 36.18959 25.86182 6.26724   1.000 33.88485  ? 55  PHE A C    1 
ATOM   864  O O    . PHE A 1 55  ? 37.05655 26.02997 7.13160   1.000 35.21406  ? 55  PHE A O    1 
ATOM   865  C CB   . PHE A 1 55  ? 36.86549 23.53900 5.57570   1.000 36.16612  ? 55  PHE A CB   1 
ATOM   866  C CG   . PHE A 1 55  ? 35.73759 22.71797 6.13644   1.000 37.03786  ? 55  PHE A CG   1 
ATOM   867  C CD1  . PHE A 1 55  ? 35.23118 22.97490 7.40086   1.000 38.91409  ? 55  PHE A CD1  1 
ATOM   868  C CD2  . PHE A 1 55  ? 35.18971 21.68020 5.40027   1.000 35.63747  ? 55  PHE A CD2  1 
ATOM   869  C CE1  . PHE A 1 55  ? 34.19291 22.21695 7.91649   1.000 37.57935  ? 55  PHE A CE1  1 
ATOM   870  C CE2  . PHE A 1 55  ? 34.15365 20.91776 5.91155   1.000 36.85033  ? 55  PHE A CE2  1 
ATOM   871  C CZ   . PHE A 1 55  ? 33.65547 21.18662 7.17121   1.000 35.62663  ? 55  PHE A CZ   1 
ATOM   872  H H    . PHE A 1 55  ? 38.27341 25.27055 4.46710   1.000 36.60177  ? 55  PHE A H    1 
ATOM   873  H HA   . PHE A 1 55  ? 35.62102 24.83133 4.58222   1.000 40.01309  ? 55  PHE A HA   1 
ATOM   874  H HB2  . PHE A 1 55  ? 37.24365 23.04996 4.82822   1.000 43.39935  ? 55  PHE A HB2  1 
ATOM   875  H HB3  . PHE A 1 55  ? 37.53039 23.64360 6.27418   1.000 43.39935  ? 55  PHE A HB3  1 
ATOM   876  H HD1  . PHE A 1 55  ? 35.59293 23.66457 7.90917   1.000 46.69691  ? 55  PHE A HD1  1 
ATOM   877  H HD2  . PHE A 1 55  ? 35.52209 21.49345 4.55201   1.000 42.76496  ? 55  PHE A HD2  1 
ATOM   878  H HE1  . PHE A 1 55  ? 33.85805 22.40197 8.76415   1.000 45.09522  ? 55  PHE A HE1  1 
ATOM   879  H HE2  . PHE A 1 55  ? 33.79319 20.22469 5.40694   1.000 44.22039  ? 55  PHE A HE2  1 
ATOM   880  H HZ   . PHE A 1 55  ? 32.95984 20.67498 7.51649   1.000 42.75196  ? 55  PHE A HZ   1 
ATOM   881  N N    . CYS A 1 56  ? 35.00643 26.47048 6.29967   1.000 32.82688  ? 56  CYS A N    1 
ATOM   882  C CA   . CYS A 1 56  ? 34.60322 27.38178 7.36441   1.000 31.44166  ? 56  CYS A CA   1 
ATOM   883  C C    . CYS A 1 56  ? 33.52172 26.69971 8.19004   1.000 33.12228  ? 56  CYS A C    1 
ATOM   884  O O    . CYS A 1 56  ? 32.48458 26.30041 7.64831   1.000 32.67161  ? 56  CYS A O    1 
ATOM   885  C CB   . CYS A 1 56  ? 34.09542 28.70327 6.78871   1.000 31.56699  ? 56  CYS A CB   1 
ATOM   886  S SG   . CYS A 1 56  ? 33.84428 30.01342 8.00674   1.000 37.27327  ? 56  CYS A SG   1 
ATOM   887  H H    . CYS A 1 56  ? 34.40246 26.36702 5.69624   1.000 39.39225  ? 56  CYS A H    1 
ATOM   888  H HA   . CYS A 1 56  ? 35.35949 27.57537 7.94016   1.000 37.72999  ? 56  CYS A HA   1 
ATOM   889  H HB2  . CYS A 1 56  ? 34.74246 29.02606 6.14215   1.000 37.88039  ? 56  CYS A HB2  1 
ATOM   890  H HB3  . CYS A 1 56  ? 33.24360 28.54220 6.35356   1.000 37.88039  ? 56  CYS A HB3  1 
ATOM   891  H HG   . CYS A 1 56  ? 34.25738 29.64229 9.07052   1.000 44.72792  ? 56  CYS A HG   1 
ATOM   892  N N    . ARG A 1 57  ? 33.76315 26.56270 9.49068   1.000 34.98243  ? 57  ARG A N    1 
ATOM   893  C CA   . ARG A 1 57  ? 32.84921 25.87729 10.39370  1.000 34.45859  ? 57  ARG A CA   1 
ATOM   894  C C    . ARG A 1 57  ? 32.32514 26.86447 11.42441  1.000 35.69745  ? 57  ARG A C    1 
ATOM   895  O O    . ARG A 1 57  ? 33.10619 27.59487 12.04250  1.000 35.50674  ? 57  ARG A O    1 
ATOM   896  C CB   . ARG A 1 57  ? 33.54258 24.70593 11.09017  1.000 43.76217  ? 57  ARG A CB   1 
ATOM   897  C CG   . ARG A 1 57  ? 32.58195 23.70075 11.68954  1.000 50.63992  ? 57  ARG A CG   1 
ATOM   898  C CD   . ARG A 1 57  ? 33.30873 22.44725 12.14204  1.000 69.89231  ? 57  ARG A CD   1 
ATOM   899  N NE   . ARG A 1 57  ? 34.49520 22.75268 12.93266  1.000 64.85503  ? 57  ARG A NE   1 
ATOM   900  C CZ   . ARG A 1 57  ? 34.50577 22.90977 14.25018  1.000 68.64426  ? 57  ARG A CZ   1 
ATOM   901  N NH1  . ARG A 1 57  ? 33.39751 22.81998 14.96801  1.000 78.94889  ? 57  ARG A NH1  1 
ATOM   902  N NH2  . ARG A 1 57  ? 35.65926 23.16224 14.86254  1.000 62.84036  ? 57  ARG A NH2  1 
ATOM   903  H H    . ARG A 1 57  ? 34.46703 26.86629 9.88053   1.000 41.97892  ? 57  ARG A H    1 
ATOM   904  H HA   . ARG A 1 57  ? 32.09494 25.53250 9.89061   1.000 41.35031  ? 57  ARG A HA   1 
ATOM   905  H HB2  . ARG A 1 57  ? 34.09385 24.23960 10.44244  1.000 52.51460  ? 57  ARG A HB2  1 
ATOM   906  H HB3  . ARG A 1 57  ? 34.09536 25.05243 11.80799  1.000 52.51460  ? 57  ARG A HB3  1 
ATOM   907  H HG2  . ARG A 1 57  ? 32.14257 24.09439 12.45954  1.000 60.76790  ? 57  ARG A HG2  1 
ATOM   908  H HG3  . ARG A 1 57  ? 31.92262 23.44873 11.02421  1.000 60.76790  ? 57  ARG A HG3  1 
ATOM   909  H HD2  . ARG A 1 57  ? 32.71138 21.91254 12.68807  1.000 83.87077  ? 57  ARG A HD2  1 
ATOM   910  H HD3  . ARG A 1 57  ? 33.58723 21.94180 11.36239  1.000 83.87077  ? 57  ARG A HD3  1 
ATOM   911  H HE   . ARG A 1 57  ? 35.24213 22.83711 12.51484  1.000 77.82604  ? 57  ARG A HE   1 
ATOM   912  H HH11 . ARG A 1 57  ? 32.64693 22.65622 14.58148  1.000 94.73867  ? 57  ARG A HH11 1 
ATOM   913  H HH12 . ARG A 1 57  ? 33.42795 22.92540 15.82098  1.000 94.73867  ? 57  ARG A HH12 1 
ATOM   914  H HH21 . ARG A 1 57  ? 36.38501 23.22165 14.40499  1.000 75.40843  ? 57  ARG A HH21 1 
ATOM   915  H HH22 . ARG A 1 57  ? 35.67930 23.26606 15.71602  1.000 75.40843  ? 57  ARG A HH22 1 
ATOM   916  N N    . LEU A 1 58  ? 31.00598 26.88494 11.60593  1.000 34.50561  ? 58  LEU A N    1 
ATOM   917  C CA   . LEU A 1 58  ? 30.34951 27.78146 12.55071  1.000 35.78570  ? 58  LEU A CA   1 
ATOM   918  C C    . LEU A 1 58  ? 29.61390 26.94647 13.59145  1.000 35.79668  ? 58  LEU A C    1 
ATOM   919  O O    . LEU A 1 58  ? 28.60820 26.29862 13.27882  1.000 34.23283  ? 58  LEU A O    1 
ATOM   920  C CB   . LEU A 1 58  ? 29.38565 28.72736 11.83610  1.000 34.35200  ? 58  LEU A CB   1 
ATOM   921  C CG   . LEU A 1 58  ? 30.01257 29.79996 10.94485  1.000 37.02563  ? 58  LEU A CG   1 
ATOM   922  C CD1  . LEU A 1 58  ? 30.54210 29.20275 9.64928   1.000 36.27222  ? 58  LEU A CD1  1 
ATOM   923  C CD2  . LEU A 1 58  ? 29.00800 30.91480 10.66021  1.000 40.77436  ? 58  LEU A CD2  1 
ATOM   924  H H    . LEU A 1 58  ? 30.45835 26.37527 11.18174  1.000 41.40673  ? 58  LEU A H    1 
ATOM   925  H HA   . LEU A 1 58  ? 31.02543 28.30963 13.00354  1.000 42.94284  ? 58  LEU A HA   1 
ATOM   926  H HB2  . LEU A 1 58  ? 28.80413 28.19343 11.27249  1.000 41.22240  ? 58  LEU A HB2  1 
ATOM   927  H HB3  . LEU A 1 58  ? 28.86238 29.18808 12.51051  1.000 41.22240  ? 58  LEU A HB3  1 
ATOM   928  H HG   . LEU A 1 58  ? 30.76827 30.18750 11.41348  1.000 44.43075  ? 58  LEU A HG   1 
ATOM   929  H HD11 . LEU A 1 58  ? 31.38392 28.75547 9.82862   1.000 43.52666  ? 58  LEU A HD11 1 
ATOM   930  H HD12 . LEU A 1 58  ? 29.89528 28.56574 9.30763   1.000 43.52666  ? 58  LEU A HD12 1 
ATOM   931  H HD13 . LEU A 1 58  ? 30.67678 29.91524 9.00499   1.000 43.52666  ? 58  LEU A HD13 1 
ATOM   932  H HD21 . LEU A 1 58  ? 28.74122 31.32137 11.49952  1.000 48.92923  ? 58  LEU A HD21 1 
ATOM   933  H HD22 . LEU A 1 58  ? 29.42597 31.57835 10.08935  1.000 48.92923  ? 58  LEU A HD22 1 
ATOM   934  H HD23 . LEU A 1 58  ? 28.23371 30.53616 10.21523  1.000 48.92923  ? 58  LEU A HD23 1 
ATOM   935  N N    . ARG A 1 59  ? 30.11407 26.96675 14.82361  1.000 35.39889  ? 59  ARG A N    1 
ATOM   936  C CA   . ARG A 1 59  ? 29.46265 26.30650 15.94749  1.000 40.91884  ? 59  ARG A CA   1 
ATOM   937  C C    . ARG A 1 59  ? 28.58829 27.32644 16.66684  1.000 41.76111  ? 59  ARG A C    1 
ATOM   938  O O    . ARG A 1 59  ? 29.08098 28.36914 17.11080  1.000 38.81915  ? 59  ARG A O    1 
ATOM   939  C CB   . ARG A 1 59  ? 30.50165 25.71203 16.89752  1.000 42.43861  ? 59  ARG A CB   1 
ATOM   940  C CG   . ARG A 1 59  ? 29.93088 25.16773 18.20168  1.000 57.06637  ? 59  ARG A CG   1 
ATOM   941  C CD   . ARG A 1 59  ? 29.02344 23.97460 17.96078  1.000 59.45221  ? 59  ARG A CD   1 
ATOM   942  N NE   . ARG A 1 59  ? 29.78603 22.78513 17.60097  1.000 77.94720  ? 59  ARG A NE   1 
ATOM   943  C CZ   . ARG A 1 59  ? 29.25431 21.65987 17.14417  1.000 77.37262  ? 59  ARG A CZ   1 
ATOM   944  N NH1  . ARG A 1 59  ? 27.94959 21.53491 16.96424  1.000 68.33410  ? 59  ARG A NH1  1 
ATOM   945  N NH2  . ARG A 1 59  ? 30.05327 20.63651 16.85543  1.000 65.23834  ? 59  ARG A NH2  1 
ATOM   946  H H    . ARG A 1 59  ? 30.84554 27.36534 15.03734  1.000 42.47867  ? 59  ARG A H    1 
ATOM   947  H HA   . ARG A 1 59  ? 28.90113 25.58266 15.62867  1.000 49.10261  ? 59  ARG A HA   1 
ATOM   948  H HB2  . ARG A 1 59  ? 30.94934 24.97958 16.44587  1.000 50.92633  ? 59  ARG A HB2  1 
ATOM   949  H HB3  . ARG A 1 59  ? 31.14307 26.40326 17.12485  1.000 50.92633  ? 59  ARG A HB3  1 
ATOM   950  H HG2  . ARG A 1 59  ? 30.65877 24.88511 18.77717  1.000 68.47965  ? 59  ARG A HG2  1 
ATOM   951  H HG3  . ARG A 1 59  ? 29.41225 25.86107 18.63895  1.000 68.47965  ? 59  ARG A HG3  1 
ATOM   952  H HD2  . ARG A 1 59  ? 28.52372 23.78307 18.76980  1.000 71.34265  ? 59  ARG A HD2  1 
ATOM   953  H HD3  . ARG A 1 59  ? 28.41352 24.17694 17.23417  1.000 71.34265  ? 59  ARG A HD3  1 
ATOM   954  H HE   . ARG A 1 59  ? 30.64072 22.81563 17.69142  1.000 93.53664  ? 59  ARG A HE   1 
ATOM   955  H HH11 . ARG A 1 59  ? 27.42569 22.19261 17.14467  1.000 82.00092  ? 59  ARG A HH11 1 
ATOM   956  H HH12 . ARG A 1 59  ? 27.62535 20.79597 16.66685  1.000 82.00092  ? 59  ARG A HH12 1 
ATOM   957  H HH21 . ARG A 1 59  ? 30.90299 20.70993 16.96575  1.000 78.28600  ? 59  ARG A HH21 1 
ATOM   958  H HH22 . ARG A 1 59  ? 29.72014 19.90139 16.55841  1.000 78.28600  ? 59  ARG A HH22 1 
ATOM   959  N N    . PHE A 1 60  ? 27.30405 27.02984 16.78233  1.000 39.22990  ? 60  PHE A N    1 
ATOM   960  C CA   . PHE A 1 60  ? 26.42504 27.99549 17.42337  1.000 42.00628  ? 60  PHE A CA   1 
ATOM   961  C C    . PHE A 1 60  ? 26.19258 27.63125 18.88423  1.000 40.82791  ? 60  PHE A C    1 
ATOM   962  O O    . PHE A 1 60  ? 26.20874 26.45301 19.25178  1.000 42.41922  ? 60  PHE A O    1 
ATOM   963  C CB   . PHE A 1 60  ? 25.09008 28.07613 16.68097  1.000 38.89825  ? 60  PHE A CB   1 
ATOM   964  C CG   . PHE A 1 60  ? 25.19500 28.75259 15.34567  1.000 36.28723  ? 60  PHE A CG   1 
ATOM   965  C CD1  . PHE A 1 60  ? 25.68499 28.06987 14.24590  1.000 34.56923  ? 60  PHE A CD1  1 
ATOM   966  C CD2  . PHE A 1 60  ? 24.82747 30.07748 15.19616  1.000 37.36266  ? 60  PHE A CD2  1 
ATOM   967  C CE1  . PHE A 1 60  ? 25.79357 28.69328 13.01847  1.000 36.85259  ? 60  PHE A CE1  1 
ATOM   968  C CE2  . PHE A 1 60  ? 24.93361 30.70573 13.97158  1.000 40.32338  ? 60  PHE A CE2  1 
ATOM   969  C CZ   . PHE A 1 60  ? 25.41817 30.01271 12.88194  1.000 36.80505  ? 60  PHE A CZ   1 
ATOM   970  H H    . PHE A 1 60  ? 26.93066 26.30501 16.50883  1.000 47.07588  ? 60  PHE A H    1 
ATOM   971  H HA   . PHE A 1 60  ? 26.82959 28.87684 17.40172  1.000 50.40754  ? 60  PHE A HA   1 
ATOM   972  H HB2  . PHE A 1 60  ? 24.75765 27.17675 16.53437  1.000 46.67790  ? 60  PHE A HB2  1 
ATOM   973  H HB3  . PHE A 1 60  ? 24.46037 28.57864 17.22120  1.000 46.67790  ? 60  PHE A HB3  1 
ATOM   974  H HD1  . PHE A 1 60  ? 25.94408 27.18110 14.33458  1.000 41.48308  ? 60  PHE A HD1  1 
ATOM   975  H HD2  . PHE A 1 60  ? 24.50512 30.55058 15.92908  1.000 44.83519  ? 60  PHE A HD2  1 
ATOM   976  H HE1  . PHE A 1 60  ? 26.11951 28.22362 12.28492  1.000 44.22311  ? 60  PHE A HE1  1 
ATOM   977  H HE2  . PHE A 1 60  ? 24.67861 31.59553 13.88136  1.000 48.38805  ? 60  PHE A HE2  1 
ATOM   978  H HZ   . PHE A 1 60  ? 25.49153 30.43482 12.05650  1.000 44.16606  ? 60  PHE A HZ   1 
ATOM   979  N N    . PRO A 1 61  ? 25.98720 28.63843 19.73879  1.000 38.47270  ? 61  PRO A N    1 
ATOM   980  C CA   . PRO A 1 61  ? 25.89629 28.36643 21.18260  1.000 45.33179  ? 61  PRO A CA   1 
ATOM   981  C C    . PRO A 1 61  ? 24.63147 27.63089 21.59171  1.000 48.34997  ? 61  PRO A C    1 
ATOM   982  O O    . PRO A 1 61  ? 24.61463 27.02690 22.67233  1.000 49.34503  ? 61  PRO A O    1 
ATOM   983  C CB   . PRO A 1 61  ? 25.95407 29.76858 21.80692  1.000 44.35810  ? 61  PRO A CB   1 
ATOM   984  C CG   . PRO A 1 61  ? 25.38752 30.66613 20.74588  1.000 42.91308  ? 61  PRO A CG   1 
ATOM   985  C CD   . PRO A 1 61  ? 25.83234 30.07365 19.43026  1.000 41.91600  ? 61  PRO A CD   1 
ATOM   986  H HA   . PRO A 1 61  ? 26.66684 27.85318 21.47196  1.000 54.39815  ? 61  PRO A HA   1 
ATOM   987  H HB2  . PRO A 1 61  ? 25.41613 29.79700 22.61359  1.000 53.22972  ? 61  PRO A HB2  1 
ATOM   988  H HB3  . PRO A 1 61  ? 26.87223 30.00488 22.01195  1.000 53.22972  ? 61  PRO A HB3  1 
ATOM   989  H HG2  . PRO A 1 61  ? 24.41962 30.67750 20.80853  1.000 51.49569  ? 61  PRO A HG2  1 
ATOM   990  H HG3  . PRO A 1 61  ? 25.73760 31.56417 20.85484  1.000 51.49569  ? 61  PRO A HG3  1 
ATOM   991  H HD2  . PRO A 1 61  ? 25.15869 30.20876 18.74554  1.000 50.29920  ? 61  PRO A HD2  1 
ATOM   992  H HD3  . PRO A 1 61  ? 26.67611 30.45859 19.14607  1.000 50.29920  ? 61  PRO A HD3  1 
ATOM   993  N N    . LYS A 1 62  ? 23.58144 27.66876 20.78715  1.000 44.39355  ? 62  LYS A N    1 
ATOM   994  C CA   . LYS A 1 62  ? 22.34707 26.94240 21.04543  1.000 48.03576  ? 62  LYS A CA   1 
ATOM   995  C C    . LYS A 1 62  ? 21.90702 26.28432 19.74609  1.000 44.43247  ? 62  LYS A C    1 
ATOM   996  O O    . LYS A 1 62  ? 22.26296 26.74519 18.66040  1.000 47.18445  ? 62  LYS A O    1 
ATOM   997  C CB   . LYS A 1 62  ? 21.23338 27.86018 21.56087  1.000 45.68385  ? 62  LYS A CB   1 
ATOM   998  C CG   . LYS A 1 62  ? 21.56705 28.60075 22.84534  1.000 60.61706  ? 62  LYS A CG   1 
ATOM   999  C CD   . LYS A 1 62  ? 20.82822 28.02088 24.03911  1.000 67.93571  ? 62  LYS A CD   1 
ATOM   1000 C CE   . LYS A 1 62  ? 21.45271 28.48420 25.34260  1.000 77.74465  ? 62  LYS A CE   1 
ATOM   1001 N NZ   . LYS A 1 62  ? 22.74536 27.79290 25.60114  1.000 80.45435  ? 62  LYS A NZ   1 
ATOM   1002 H H    . LYS A 1 62  ? 23.55847 28.12485 20.05842  1.000 53.27226  ? 62  LYS A H    1 
ATOM   1003 H HA   . LYS A 1 62  ? 22.50370 26.25895 21.71571  1.000 57.64291  ? 62  LYS A HA   1 
ATOM   1004 H HB2  . LYS A 1 62  ? 21.04235 28.52520 20.88104  1.000 54.82062  ? 62  LYS A HB2  1 
ATOM   1005 H HB3  . LYS A 1 62  ? 20.44402 27.32239 21.72996  1.000 54.82062  ? 62  LYS A HB3  1 
ATOM   1006 H HG2  . LYS A 1 62  ? 22.51957 28.53305 23.01572  1.000 72.74048  ? 62  LYS A HG2  1 
ATOM   1007 H HG3  . LYS A 1 62  ? 21.31182 29.53205 22.75349  1.000 72.74048  ? 62  LYS A HG3  1 
ATOM   1008 H HD2  . LYS A 1 62  ? 19.90370 28.31381 24.02047  1.000 81.52285  ? 62  LYS A HD2  1 
ATOM   1009 H HD3  . LYS A 1 62  ? 20.87011 27.05236 24.00585  1.000 81.52285  ? 62  LYS A HD3  1 
ATOM   1010 H HE2  . LYS A 1 62  ? 21.62032 29.43855 25.29750  1.000 93.29357  ? 62  LYS A HE2  1 
ATOM   1011 H HE3  . LYS A 1 62  ? 20.84912 28.28767 26.07605  1.000 93.29357  ? 62  LYS A HE3  1 
ATOM   1012 H HZ1  . LYS A 1 62  ? 23.10310 28.09016 26.35993  1.000 96.54522  ? 62  LYS A HZ1  1 
ATOM   1013 H HZ2  . LYS A 1 62  ? 22.61311 26.91536 25.66848  1.000 96.54522  ? 62  LYS A HZ2  1 
ATOM   1014 H HZ3  . LYS A 1 62  ? 23.31291 27.94908 24.93361  1.000 96.54522  ? 62  LYS A HZ3  1 
ATOM   1015 N N    . PRO A 1 63  ? 21.13497 25.20172 19.83343  1.000 46.18948  ? 63  PRO A N    1 
ATOM   1016 C CA   . PRO A 1 63  ? 20.55633 24.62372 18.61172  1.000 44.15731  ? 63  PRO A CA   1 
ATOM   1017 C C    . PRO A 1 63  ? 19.78961 25.67468 17.82566  1.000 44.71414  ? 63  PRO A C    1 
ATOM   1018 O O    . PRO A 1 63  ? 18.95979 26.40272 18.37363  1.000 46.75484  ? 63  PRO A O    1 
ATOM   1019 C CB   . PRO A 1 63  ? 19.62926 23.52428 19.14736  1.000 46.30039  ? 63  PRO A CB   1 
ATOM   1020 C CG   . PRO A 1 63  ? 20.22172 23.14492 20.46758  1.000 50.03023  ? 63  PRO A CG   1 
ATOM   1021 C CD   . PRO A 1 63  ? 20.76943 24.43185 21.03652  1.000 46.94520  ? 63  PRO A CD   1 
ATOM   1022 H HA   . PRO A 1 63  ? 21.24274 24.22656 18.05315  1.000 52.98878  ? 63  PRO A HA   1 
ATOM   1023 H HB2  . PRO A 1 63  ? 18.73000 23.87152 19.25531  1.000 55.56047  ? 63  PRO A HB2  1 
ATOM   1024 H HB3  . PRO A 1 63  ? 19.62253 22.76951 18.53812  1.000 55.56047  ? 63  PRO A HB3  1 
ATOM   1025 H HG2  . PRO A 1 63  ? 19.53451 22.77603 21.04426  1.000 60.03627  ? 63  PRO A HG2  1 
ATOM   1026 H HG3  . PRO A 1 63  ? 20.92970 22.49477 20.33734  1.000 60.03627  ? 63  PRO A HG3  1 
ATOM   1027 H HD2  . PRO A 1 63  ? 20.09276 24.89738 21.55256  1.000 56.33424  ? 63  PRO A HD2  1 
ATOM   1028 H HD3  . PRO A 1 63  ? 21.54887 24.26186 21.58831  1.000 56.33424  ? 63  PRO A HD3  1 
ATOM   1029 N N    . ILE A 1 64  ? 20.07945 25.76346 16.53182  1.000 43.22672  ? 64  ILE A N    1 
ATOM   1030 C CA   . ILE A 1 64  ? 19.35636 26.65578 15.63252  1.000 42.65441  ? 64  ILE A CA   1 
ATOM   1031 C C    . ILE A 1 64  ? 18.35763 25.88546 14.77753  1.000 40.80127  ? 64  ILE A C    1 
ATOM   1032 O O    . ILE A 1 64  ? 17.17302 26.21727 14.74362  1.000 46.12669  ? 64  ILE A O    1 
ATOM   1033 C CB   . ILE A 1 64  ? 20.34219 27.45539 14.75107  1.000 49.59869  ? 64  ILE A CB   1 
ATOM   1034 C CG1  . ILE A 1 64  ? 21.40951 28.14717 15.60593  1.000 46.34571  ? 64  ILE A CG1  1 
ATOM   1035 C CG2  . ILE A 1 64  ? 19.58866 28.49155 13.92509  1.000 47.98810  ? 64  ILE A CG2  1 
ATOM   1036 C CD1  . ILE A 1 64  ? 20.86672 29.20086 16.56511  1.000 50.35694  ? 64  ILE A CD1  1 
ATOM   1037 H H    . ILE A 1 64  ? 20.70000 25.31013 16.14579  1.000 51.87207  ? 64  ILE A H    1 
ATOM   1038 H HA   . ILE A 1 64  ? 18.86145 27.29292 16.17105  1.000 51.18529  ? 64  ILE A HA   1 
ATOM   1039 H HB   . ILE A 1 64  ? 20.78440 26.82912 14.15682  1.000 59.51843  ? 64  ILE A HB   1 
ATOM   1040 H HG12 . ILE A 1 64  ? 21.86402 27.47442 16.13670  1.000 55.61486  ? 64  ILE A HG12 1 
ATOM   1041 H HG13 . ILE A 1 64  ? 22.04133 28.58648 15.01540  1.000 55.61486  ? 64  ILE A HG13 1 
ATOM   1042 H HG21 . ILE A 1 64  ? 19.06912 28.03576 13.24447  1.000 57.58572  ? 64  ILE A HG21 1 
ATOM   1043 H HG22 . ILE A 1 64  ? 18.99974 28.99387 14.50967  1.000 57.58572  ? 64  ILE A HG22 1 
ATOM   1044 H HG23 . ILE A 1 64  ? 20.22881 29.08900 13.50776  1.000 57.58572  ? 64  ILE A HG23 1 
ATOM   1045 H HD11 . ILE A 1 64  ? 21.60156 29.56461 17.08336  1.000 60.42832  ? 64  ILE A HD11 1 
ATOM   1046 H HD12 . ILE A 1 64  ? 20.44266 29.90644 16.05205  1.000 60.42832  ? 64  ILE A HD12 1 
ATOM   1047 H HD13 . ILE A 1 64  ? 20.21868 28.78622 17.15589  1.000 60.42832  ? 64  ILE A HD13 1 
ATOM   1048 N N    . ARG A 1 65  ? 18.82045 24.84698 14.07790  1.000 43.06398  ? 65  ARG A N    1 
ATOM   1049 C CA   . ARG A 1 65  ? 17.95675 24.02540 13.22847  1.000 42.49721  ? 65  ARG A CA   1 
ATOM   1050 C C    . ARG A 1 65  ? 17.56965 22.77422 14.01151  1.000 45.17615  ? 65  ARG A C    1 
ATOM   1051 O O    . ARG A 1 65  ? 18.11982 21.68882 13.82653  1.000 46.90508  ? 65  ARG A O    1 
ATOM   1052 C CB   . ARG A 1 65  ? 18.65381 23.67360 11.91791  1.000 45.71069  ? 65  ARG A CB   1 
ATOM   1053 C CG   . ARG A 1 65  ? 18.56275 24.74874 10.84897  1.000 45.87983  ? 65  ARG A CG   1 
ATOM   1054 C CD   . ARG A 1 65  ? 17.13361 24.94691 10.35672  1.000 47.60060  ? 65  ARG A CD   1 
ATOM   1055 N NE   . ARG A 1 65  ? 16.62408 23.79781 9.61655   1.000 46.08947  ? 65  ARG A NE   1 
ATOM   1056 C CZ   . ARG A 1 65  ? 16.87682 23.55882 8.33652   1.000 45.82484  ? 65  ARG A CZ   1 
ATOM   1057 N NH1  . ARG A 1 65  ? 17.67905 24.34073 7.63302   1.000 48.35185  ? 65  ARG A NH1  1 
ATOM   1058 N NH2  . ARG A 1 65  ? 16.31076 22.50895 7.74785   1.000 50.09907  ? 65  ARG A NH2  1 
ATOM   1059 H H    . ARG A 1 65  ? 19.64281 24.59533 14.07926  1.000 51.67677  ? 65  ARG A H    1 
ATOM   1060 H HA   . ARG A 1 65  ? 17.15303 24.52727 13.02097  1.000 50.99665  ? 65  ARG A HA   1 
ATOM   1061 H HB2  . ARG A 1 65  ? 19.59414 23.51972 12.09958  1.000 54.85283  ? 65  ARG A HB2  1 
ATOM   1062 H HB3  . ARG A 1 65  ? 18.24914 22.86839 11.55904  1.000 54.85283  ? 65  ARG A HB3  1 
ATOM   1063 H HG2  . ARG A 1 65  ? 18.87595 25.59049 11.21539  1.000 55.05580  ? 65  ARG A HG2  1 
ATOM   1064 H HG3  . ARG A 1 65  ? 19.11100 24.49242 10.09093  1.000 55.05580  ? 65  ARG A HG3  1 
ATOM   1065 H HD2  . ARG A 1 65  ? 16.55371 25.09179 11.12067  1.000 57.12071  ? 65  ARG A HD2  1 
ATOM   1066 H HD3  . ARG A 1 65  ? 17.10624 25.71774 9.76852   1.000 57.12071  ? 65  ARG A HD3  1 
ATOM   1067 H HE   . ARG A 1 65  ? 16.12633 23.23761 10.03848  1.000 55.30736  ? 65  ARG A HE   1 
ATOM   1068 H HH11 . ARG A 1 65  ? 18.05003 25.02186 8.00456   1.000 58.02223  ? 65  ARG A HH11 1 
ATOM   1069 H HH12 . ARG A 1 65  ? 17.82962 24.16794 6.80412   1.000 58.02223  ? 65  ARG A HH12 1 
ATOM   1070 H HH21 . ARG A 1 65  ? 15.78784 21.99445 8.19669   1.000 60.11888  ? 65  ARG A HH21 1 
ATOM   1071 H HH22 . ARG A 1 65  ? 16.46767 22.34465 6.91841   1.000 60.11888  ? 65  ARG A HH22 1 
ATOM   1072 N N    . THR A 1 66  ? 16.59236 22.94067 14.90083  1.000 47.02779  ? 66  THR A N    1 
ATOM   1073 C CA   . THR A 1 66  ? 16.14387 21.84143 15.74327  1.000 45.30487  ? 66  THR A CA   1 
ATOM   1074 C C    . THR A 1 66  ? 15.43143 20.74657 14.96047  1.000 49.03921  ? 66  THR A C    1 
ATOM   1075 O O    . THR A 1 66  ? 15.24803 19.64832 15.49700  1.000 51.91427  ? 66  THR A O    1 
ATOM   1076 C CB   . THR A 1 66  ? 15.21954 22.38044 16.83811  1.000 47.67607  ? 66  THR A CB   1 
ATOM   1077 O OG1  . THR A 1 66  ? 14.06583 22.98650 16.24140  1.000 55.73704  ? 66  THR A OG1  1 
ATOM   1078 C CG2  . THR A 1 66  ? 15.94740 23.41719 17.68001  1.000 49.96683  ? 66  THR A CG2  1 
ATOM   1079 H H    . THR A 1 66  ? 16.17472 23.68060 15.03377  1.000 56.43335  ? 66  THR A H    1 
ATOM   1080 H HA   . THR A 1 66  ? 16.91674 21.43821 16.16870  1.000 54.36584  ? 66  THR A HA   1 
ATOM   1081 H HB   . THR A 1 66  ? 14.94044 21.65134 17.41379  1.000 57.21128  ? 66  THR A HB   1 
ATOM   1082 H HG1  . THR A 1 66  ? 14.29722 23.64159 15.76926  1.000 66.88445  ? 66  THR A HG1  1 
ATOM   1083 H HG21 . THR A 1 66  ? 16.76936 23.04108 18.03191  1.000 59.96020  ? 66  THR A HG21 1 
ATOM   1084 H HG22 . THR A 1 66  ? 16.16259 24.19263 17.13845  1.000 59.96020  ? 66  THR A HG22 1 
ATOM   1085 H HG23 . THR A 1 66  ? 15.38655 23.69627 18.42059  1.000 59.96020  ? 66  THR A HG23 1 
ATOM   1086 N N    . ASP A 1 67  ? 15.03580 21.00935 13.71470  1.000 48.02862  ? 67  ASP A N    1 
ATOM   1087 C CA   . ASP A 1 67  ? 14.32230 20.02090 12.91799  1.000 49.74764  ? 67  ASP A CA   1 
ATOM   1088 C C    . ASP A 1 67  ? 15.24424 19.00488 12.25680  1.000 47.55896  ? 67  ASP A C    1 
ATOM   1089 O O    . ASP A 1 67  ? 14.74687 18.02599 11.68919  1.000 51.31119  ? 67  ASP A O    1 
ATOM   1090 C CB   . ASP A 1 67  ? 13.49099 20.71889 11.83727  1.000 53.35917  ? 67  ASP A CB   1 
ATOM   1091 C CG   . ASP A 1 67  ? 14.33302 21.60694 10.94076  1.000 51.03293  ? 67  ASP A CG   1 
ATOM   1092 O OD1  . ASP A 1 67  ? 15.25000 22.27430 11.46313  1.000 48.14912  ? 67  ASP A OD1  1 
ATOM   1093 O OD2  . ASP A 1 67  ? 14.08531 21.63498 9.71792   1.000 49.10581  ? 67  ASP A OD2  1 
ATOM   1094 H H    . ASP A 1 67  ? 15.17043 21.75596 13.30967  1.000 57.63434  ? 67  ASP A H    1 
ATOM   1095 H HA   . ASP A 1 67  ? 13.71805 19.53821 13.50348  1.000 59.69717  ? 67  ASP A HA   1 
ATOM   1096 H HB2  . ASP A 1 67  ? 13.06516 20.04742 11.28167  1.000 64.03100  ? 67  ASP A HB2  1 
ATOM   1097 H HB3  . ASP A 1 67  ? 12.81797 21.27260 12.26311  1.000 64.03100  ? 67  ASP A HB3  1 
ATOM   1098 N N    . VAL A 1 68  ? 16.55887 19.20595 12.31128  1.000 45.52867  ? 68  VAL A N    1 
ATOM   1099 C CA   . VAL A 1 68  ? 17.50698 18.30995 11.66597  1.000 46.03292  ? 68  VAL A CA   1 
ATOM   1100 C C    . VAL A 1 68  ? 18.25320 17.51116 12.72625  1.000 48.86439  ? 68  VAL A C    1 
ATOM   1101 O O    . VAL A 1 68  ? 18.32831 17.88808 13.90037  1.000 48.27901  ? 68  VAL A O    1 
ATOM   1102 C CB   . VAL A 1 68  ? 18.50708 19.06734 10.76535  1.000 45.90048  ? 68  VAL A CB   1 
ATOM   1103 C CG1  . VAL A 1 68  ? 17.76970 19.99897 9.81783   1.000 47.49905  ? 68  VAL A CG1  1 
ATOM   1104 C CG2  . VAL A 1 68  ? 19.52283 19.82587 11.61662  1.000 49.32695  ? 68  VAL A CG2  1 
ATOM   1105 H H    . VAL A 1 68  ? 16.92850 19.86460 12.72257  1.000 54.63440  ? 68  VAL A H    1 
ATOM   1106 H HA   . VAL A 1 68  ? 17.00764 17.68654 11.11559  1.000 55.23950  ? 68  VAL A HA   1 
ATOM   1107 H HB   . VAL A 1 68  ? 18.99690 18.42815 10.22460  1.000 55.08058  ? 68  VAL A HB   1 
ATOM   1108 H HG11 . VAL A 1 68  ? 16.83780 19.73317 9.77522   1.000 56.99886  ? 68  VAL A HG11 1 
ATOM   1109 H HG12 . VAL A 1 68  ? 17.83966 20.90755 10.15023  1.000 56.99886  ? 68  VAL A HG12 1 
ATOM   1110 H HG13 . VAL A 1 68  ? 18.17194 19.93698 8.93734   1.000 56.99886  ? 68  VAL A HG13 1 
ATOM   1111 H HG21 . VAL A 1 68  ? 20.30247 19.26501 11.75259  1.000 59.19234  ? 68  VAL A HG21 1 
ATOM   1112 H HG22 . VAL A 1 68  ? 19.77738 20.63968 11.15422  1.000 59.19234  ? 68  VAL A HG22 1 
ATOM   1113 H HG23 . VAL A 1 68  ? 19.11883 20.04354 12.47120  1.000 59.19234  ? 68  VAL A HG23 1 
ATOM   1114 N N    . THR A 1 69  ? 18.82119 16.39287 12.28935  1.000 49.81201  ? 69  THR A N    1 
ATOM   1115 C CA   . THR A 1 69  ? 19.62219 15.51971 13.13010  1.000 53.11861  ? 69  THR A CA   1 
ATOM   1116 C C    . THR A 1 69  ? 21.10619 15.74153 12.85171  1.000 47.43640  ? 69  THR A C    1 
ATOM   1117 O O    . THR A 1 69  ? 21.49261 16.31800 11.83170  1.000 48.25700  ? 69  THR A O    1 
ATOM   1118 C CB   . THR A 1 69  ? 19.25871 14.05271 12.88523  1.000 48.09215  ? 69  THR A CB   1 
ATOM   1119 O OG1  . THR A 1 69  ? 19.58809 13.69575 11.53628  1.000 51.70097  ? 69  THR A OG1  1 
ATOM   1120 C CG2  . THR A 1 69  ? 17.76702 13.82373 13.11936  1.000 45.99850  ? 69  THR A CG2  1 
ATOM   1121 H H    . THR A 1 69  ? 18.75293 16.11079 11.47981  1.000 59.77441  ? 69  THR A H    1 
ATOM   1122 H HA   . THR A 1 69  ? 19.45031 15.72078 14.06334  1.000 63.74233  ? 69  THR A HA   1 
ATOM   1123 H HB   . THR A 1 69  ? 19.75459 13.48926 13.49967  1.000 57.71058  ? 69  THR A HB   1 
ATOM   1124 H HG1  . THR A 1 69  ? 19.41421 12.88482 11.40306  1.000 62.04117  ? 69  THR A HG1  1 
ATOM   1125 H HG21 . THR A 1 69  ? 17.52310 14.11319 14.01245  1.000 55.19820  ? 69  THR A HG21 1 
ATOM   1126 H HG22 . THR A 1 69  ? 17.24852 14.32746 12.47258  1.000 55.19820  ? 69  THR A HG22 1 
ATOM   1127 H HG23 . THR A 1 69  ? 17.55731 12.88132 13.02562  1.000 55.19820  ? 69  THR A HG23 1 
ATOM   1128 N N    . GLY A 1 70  ? 21.93706 15.27724 13.77856  1.000 46.89116  ? 70  GLY A N    1 
ATOM   1129 C CA   . GLY A 1 70  ? 23.37242 15.36560 13.60480  1.000 44.93440  ? 70  GLY A CA   1 
ATOM   1130 C C    . GLY A 1 70  ? 23.85096 14.36302 12.56774  1.000 45.45603  ? 70  GLY A C    1 
ATOM   1131 O O    . GLY A 1 70  ? 23.72985 13.14533 12.77356  1.000 52.62666  ? 70  GLY A O    1 
ATOM   1132 H H    . GLY A 1 70  ? 21.69098 14.90757 14.51503  1.000 56.26939  ? 70  GLY A H    1 
ATOM   1133 H HA2  . GLY A 1 70  ? 23.61288 16.25811 13.31068  1.000 53.92128  ? 70  GLY A HA2  1 
ATOM   1134 H HA3  . GLY A 1 70  ? 23.81677 15.18016 14.44686  1.000 53.92128  ? 70  GLY A HA3  1 
ATOM   1135 N N    . MET A 1 71  ? 24.38811 14.85802 11.45742  1.000 47.93429  ? 71  MET A N    1 
ATOM   1136 C CA   . MET A 1 71  ? 24.94871 13.99899 10.42809  1.000 41.17256  ? 71  MET A CA   1 
ATOM   1137 C C    . MET A 1 71  ? 26.40661 13.66921 10.73395  1.000 43.89583  ? 71  MET A C    1 
ATOM   1138 O O    . MET A 1 71  ? 27.05772 14.29702 11.57244  1.000 45.53715  ? 71  MET A O    1 
ATOM   1139 C CB   . MET A 1 71  ? 24.86113 14.66838 9.05645   1.000 44.33540  ? 71  MET A CB   1 
ATOM   1140 C CG   . MET A 1 71  ? 23.54622 14.47946 8.33023   1.000 57.33873  ? 71  MET A CG   1 
ATOM   1141 S SD   . MET A 1 71  ? 23.57154 15.22210 6.68138   1.000 53.68780  ? 71  MET A SD   1 
ATOM   1142 C CE   . MET A 1 71  ? 25.16210 14.67456 6.05908   1.000 36.01399  ? 71  MET A CE   1 
ATOM   1143 H H    . MET A 1 71  ? 24.43905 15.69745 11.27752  1.000 57.52114  ? 71  MET A H    1 
ATOM   1144 H HA   . MET A 1 71  ? 24.42783 13.18103 10.40543  1.000 49.40707  ? 71  MET A HA   1 
ATOM   1145 H HB2  . MET A 1 71  ? 24.99416 15.62223 9.17211   1.000 53.20248  ? 71  MET A HB2  1 
ATOM   1146 H HB3  . MET A 1 71  ? 25.55959 14.30207 8.49175   1.000 53.20248  ? 71  MET A HB3  1 
ATOM   1147 H HG2  . MET A 1 71  ? 23.36879 13.53080 8.23296   1.000 68.80648  ? 71  MET A HG2  1 
ATOM   1148 H HG3  . MET A 1 71  ? 22.83636 14.89907 8.84105   1.000 68.80648  ? 71  MET A HG3  1 
ATOM   1149 H HE1  . MET A 1 71  ? 25.28367 15.01588 5.15929   1.000 43.21679  ? 71  MET A HE1  1 
ATOM   1150 H HE2  . MET A 1 71  ? 25.86184 15.01379 6.63889   1.000 43.21679  ? 71  MET A HE2  1 
ATOM   1151 H HE3  . MET A 1 71  ? 25.18095 13.70478 6.05035   1.000 43.21679  ? 71  MET A HE3  1 
ATOM   1152 N N    . ILE A 1 72  ? 26.91929 12.66972 10.02416  1.000 46.26239  ? 72  ILE A N    1 
ATOM   1153 C CA   . ILE A 1 72  ? 28.34092 12.35448 10.06314  1.000 42.94882  ? 72  ILE A CA   1 
ATOM   1154 C C    . ILE A 1 72  ? 29.07642 13.33168 9.15723   1.000 42.12850  ? 72  ILE A C    1 
ATOM   1155 O O    . ILE A 1 72  ? 28.67662 13.55843 8.00902   1.000 40.91982  ? 72  ILE A O    1 
ATOM   1156 C CB   . ILE A 1 72  ? 28.59279 10.89902 9.63510   1.000 48.44421  ? 72  ILE A CB   1 
ATOM   1157 C CG1  . ILE A 1 72  ? 27.90241 9.93934  10.60902  1.000 48.78263  ? 72  ILE A CG1  1 
ATOM   1158 C CG2  . ILE A 1 72  ? 30.09386 10.60696 9.55115   1.000 50.78796  ? 72  ILE A CG2  1 
ATOM   1159 C CD1  . ILE A 1 72  ? 28.40506 8.51412  10.52897  1.000 50.48573  ? 72  ILE A CD1  1 
ATOM   1160 H H    . ILE A 1 72  ? 26.46091 12.15604 9.50878   1.000 55.51487  ? 72  ILE A H    1 
ATOM   1161 H HA   . ILE A 1 72  ? 28.67049 12.46044 10.96926  1.000 51.53859  ? 72  ILE A HA   1 
ATOM   1162 H HB   . ILE A 1 72  ? 28.21484 10.76866 8.75133   1.000 58.13305  ? 72  ILE A HB   1 
ATOM   1163 H HG12 . ILE A 1 72  ? 28.05158 10.25438 11.51423  1.000 58.53915  ? 72  ILE A HG12 1 
ATOM   1164 H HG13 . ILE A 1 72  ? 26.95230 9.92849  10.41386  1.000 58.53915  ? 72  ILE A HG13 1 
ATOM   1165 H HG21 . ILE A 1 72  ? 30.22417 9.74000  9.13605   1.000 60.94556  ? 72  ILE A HG21 1 
ATOM   1166 H HG22 . ILE A 1 72  ? 30.52038 11.29625 9.01837   1.000 60.94556  ? 72  ILE A HG22 1 
ATOM   1167 H HG23 . ILE A 1 72  ? 30.46559 10.60396 10.44709  1.000 60.94556  ? 72  ILE A HG23 1 
ATOM   1168 H HD11 . ILE A 1 72  ? 27.77420 7.93099  10.97938  1.000 60.58287  ? 72  ILE A HD11 1 
ATOM   1169 H HD12 . ILE A 1 72  ? 28.48377 8.25892  9.59645   1.000 60.58287  ? 72  ILE A HD12 1 
ATOM   1170 H HD13 . ILE A 1 72  ? 29.27189 8.46024  10.96095  1.000 60.58287  ? 72  ILE A HD13 1 
ATOM   1171 N N    . LEU A 1 73  ? 30.14665 13.92121 9.67909   1.000 43.11659  ? 73  LEU A N    1 
ATOM   1172 C CA   . LEU A 1 73  ? 31.06384 14.74353 8.90551   1.000 43.45474  ? 73  LEU A CA   1 
ATOM   1173 C C    . LEU A 1 73  ? 32.42551 14.06734 8.90279   1.000 38.76970  ? 73  LEU A C    1 
ATOM   1174 O O    . LEU A 1 73  ? 32.96995 13.75964 9.96822   1.000 43.32780  ? 73  LEU A O    1 
ATOM   1175 C CB   . LEU A 1 73  ? 31.17224 16.15167 9.48660   1.000 44.67478  ? 73  LEU A CB   1 
ATOM   1176 C CG   . LEU A 1 73  ? 32.25944 17.04721 8.89174   1.000 40.78865  ? 73  LEU A CG   1 
ATOM   1177 C CD1  . LEU A 1 73  ? 32.01179 17.29188 7.41224   1.000 42.89412  ? 73  LEU A CD1  1 
ATOM   1178 C CD2  . LEU A 1 73  ? 32.32394 18.35996 9.65794   1.000 37.01114  ? 73  LEU A CD2  1 
ATOM   1179 H H    . LEU A 1 73  ? 30.36803 13.85602 10.50755  1.000 51.73991  ? 73  LEU A H    1 
ATOM   1180 H HA   . LEU A 1 73  ? 30.74806 14.82322 7.99182   1.000 52.14568  ? 73  LEU A HA   1 
ATOM   1181 H HB2  . LEU A 1 73  ? 30.32388 16.60106 9.34789   1.000 53.60973  ? 73  LEU A HB2  1 
ATOM   1182 H HB3  . LEU A 1 73  ? 31.35448 16.07268 10.43605  1.000 53.60973  ? 73  LEU A HB3  1 
ATOM   1183 H HG   . LEU A 1 73  ? 33.11888 16.60441 8.97040   1.000 48.94639  ? 73  LEU A HG   1 
ATOM   1184 H HD11 . LEU A 1 73  ? 31.12587 17.67022 7.29867   1.000 51.47294  ? 73  LEU A HD11 1 
ATOM   1185 H HD12 . LEU A 1 73  ? 32.68069 17.90977 7.07803   1.000 51.47294  ? 73  LEU A HD12 1 
ATOM   1186 H HD13 . LEU A 1 73  ? 32.07446 16.44815 6.93779   1.000 51.47294  ? 73  LEU A HD13 1 
ATOM   1187 H HD21 . LEU A 1 73  ? 32.51909 18.17266 10.58946  1.000 44.41336  ? 73  LEU A HD21 1 
ATOM   1188 H HD22 . LEU A 1 73  ? 33.02424 18.91327 9.27804   1.000 44.41336  ? 73  LEU A HD22 1 
ATOM   1189 H HD23 . LEU A 1 73  ? 31.46865 18.81144 9.58346   1.000 44.41336  ? 73  LEU A HD23 1 
ATOM   1190 N N    . GLU A 1 74  ? 32.97261 13.84293 7.71151   1.000 43.91752  ? 74  GLU A N    1 
ATOM   1191 C CA   . GLU A 1 74  ? 34.26291 13.19003 7.55312   1.000 43.28090  ? 74  GLU A CA   1 
ATOM   1192 C C    . GLU A 1 74  ? 35.11940 13.99073 6.58427   1.000 39.96754  ? 74  GLU A C    1 
ATOM   1193 O O    . GLU A 1 74  ? 34.61822 14.80316 5.80291   1.000 39.96814  ? 74  GLU A O    1 
ATOM   1194 C CB   . GLU A 1 74  ? 34.09086 11.74800 7.06063   1.000 44.60685  ? 74  GLU A CB   1 
ATOM   1195 C CG   . GLU A 1 74  ? 33.13484 10.94629 7.92808   1.000 49.71483  ? 74  GLU A CG   1 
ATOM   1196 C CD   . GLU A 1 74  ? 33.18018 9.46276  7.64694   1.000 47.77387  ? 74  GLU A CD   1 
ATOM   1197 O OE1  . GLU A 1 74  ? 33.39497 9.07804  6.47862   1.000 53.39622  ? 74  GLU A OE1  1 
ATOM   1198 O OE2  . GLU A 1 74  ? 33.00299 8.67503  8.59951   1.000 47.70760  ? 74  GLU A OE2  1 
ATOM   1199 H H    . GLU A 1 74  ? 32.60586 14.06537 6.96612   1.000 52.70103  ? 74  GLU A H    1 
ATOM   1200 H HA   . GLU A 1 74  ? 34.72962 13.16421 8.40306   1.000 51.93709  ? 74  GLU A HA   1 
ATOM   1201 H HB2  . GLU A 1 74  ? 33.73816 11.76209 6.15714   1.000 53.52822  ? 74  GLU A HB2  1 
ATOM   1202 H HB3  . GLU A 1 74  ? 34.95331 11.30425 7.07322   1.000 53.52822  ? 74  GLU A HB3  1 
ATOM   1203 H HG2  . GLU A 1 74  ? 33.36781 11.08054 8.86007   1.000 59.65779  ? 74  GLU A HG2  1 
ATOM   1204 H HG3  . GLU A 1 74  ? 32.22928 11.25328 7.76493   1.000 59.65779  ? 74  GLU A HG3  1 
ATOM   1205 N N    . GLU A 1 75  ? 36.42812 13.75837 6.65456   1.000 42.91604  ? 75  GLU A N    1 
ATOM   1206 C CA   . GLU A 1 75  ? 37.38821 14.46217 5.80833   1.000 44.38167  ? 75  GLU A CA   1 
ATOM   1207 C C    . GLU A 1 75  ? 37.44782 13.75503 4.46195   1.000 47.13058  ? 75  GLU A C    1 
ATOM   1208 O O    . GLU A 1 75  ? 38.22535 12.82232 4.25343   1.000 46.58350  ? 75  GLU A O    1 
ATOM   1209 C CB   . GLU A 1 75  ? 38.76067 14.51397 6.46549   1.000 52.07646  ? 75  GLU A CB   1 
ATOM   1210 C CG   . GLU A 1 75  ? 39.79007 15.26531 5.63735   1.000 58.56444  ? 75  GLU A CG   1 
ATOM   1211 C CD   . GLU A 1 75  ? 41.13136 15.37913 6.32771   1.000 77.46036  ? 75  GLU A CD   1 
ATOM   1212 O OE1  . GLU A 1 75  ? 41.31441 14.74447 7.38700   1.000 70.89730  ? 75  GLU A OE1  1 
ATOM   1213 O OE2  . GLU A 1 75  ? 42.00443 16.10634 5.81055   1.000 86.50475  ? 75  GLU A OE2  1 
ATOM   1214 H H    . GLU A 1 75  ? 36.78858 13.19093 7.19092   1.000 51.49925  ? 75  GLU A H    1 
ATOM   1215 H HA   . GLU A 1 75  ? 37.08068 15.37172 5.67037   1.000 53.25801  ? 75  GLU A HA   1 
ATOM   1216 H HB2  . GLU A 1 75  ? 38.68216 14.96139 7.32254   1.000 62.49175  ? 75  GLU A HB2  1 
ATOM   1217 H HB3  . GLU A 1 75  ? 39.08279 13.60788 6.59253   1.000 62.49175  ? 75  GLU A HB3  1 
ATOM   1218 H HG2  . GLU A 1 75  ? 39.92379 14.79628 4.79889   1.000 70.27733  ? 75  GLU A HG2  1 
ATOM   1219 H HG3  . GLU A 1 75  ? 39.46392 16.16283 5.46708   1.000 70.27733  ? 75  GLU A HG3  1 
ATOM   1220 N N    . GLY A 1 76  ? 36.62033 14.21110 3.53148   1.000 38.07405  ? 76  GLY A N    1 
ATOM   1221 C CA   . GLY A 1 76  ? 36.56980 13.60891 2.21599   1.000 38.93042  ? 76  GLY A CA   1 
ATOM   1222 C C    . GLY A 1 76  ? 35.96401 12.21747 2.26488   1.000 38.49496  ? 76  GLY A C    1 
ATOM   1223 O O    . GLY A 1 76  ? 35.49387 11.73672 3.29478   1.000 36.68991  ? 76  GLY A O    1 
ATOM   1224 H H    . GLY A 1 76  ? 36.07828 14.86974 3.64091   1.000 45.68886  ? 76  GLY A H    1 
ATOM   1225 H HA2  . GLY A 1 76  ? 36.03151 14.16034 1.62688   1.000 46.71651  ? 76  GLY A HA2  1 
ATOM   1226 H HA3  . GLY A 1 76  ? 37.46742 13.54317 1.85425   1.000 46.71651  ? 76  GLY A HA3  1 
ATOM   1227 N N    . ALA A 1 77  ? 35.97313 11.56935 1.10832   1.000 32.13991  ? 77  ALA A N    1 
ATOM   1228 C CA   . ALA A 1 77  ? 35.50459 10.20469 0.94758   1.000 37.76008  ? 77  ALA A CA   1 
ATOM   1229 C C    . ALA A 1 77  ? 36.65996 9.31604  0.50795   1.000 40.47129  ? 77  ALA A C    1 
ATOM   1230 O O    . ALA A 1 77  ? 37.67645 9.80896  0.00404   1.000 38.88091  ? 77  ALA A O    1 
ATOM   1231 C CB   . ALA A 1 77  ? 34.37356 10.12448 -0.08774  1.000 39.27068  ? 77  ALA A CB   1 
ATOM   1232 H H    . ALA A 1 77  ? 36.25817 11.91576 0.37460   1.000 38.56789  ? 77  ALA A H    1 
ATOM   1233 H HA   . ALA A 1 77  ? 35.15929 9.87771  1.79301   1.000 45.31209  ? 77  ALA A HA   1 
ATOM   1234 H HB1  . ALA A 1 77  ? 33.63344 10.67643 0.20970   1.000 47.12481  ? 77  ALA A HB1  1 
ATOM   1235 H HB2  . ALA A 1 77  ? 34.70354 10.44570 -0.94145  1.000 47.12481  ? 77  ALA A HB2  1 
ATOM   1236 H HB3  . ALA A 1 77  ? 34.08583 9.20182  -0.17028  1.000 47.12481  ? 77  ALA A HB3  1 
ATOM   1237 N N    . PRO A 1 78  ? 36.54299 8.00166  0.68875   1.000 39.30903  ? 78  PRO A N    1 
ATOM   1238 C CA   . PRO A 1 78  ? 37.57053 7.09952  0.15608   1.000 40.64217  ? 78  PRO A CA   1 
ATOM   1239 C C    . PRO A 1 78  ? 37.75967 7.33504  -1.33350  1.000 41.52691  ? 78  PRO A C    1 
ATOM   1240 O O    . PRO A 1 78  ? 36.80678 7.62306  -2.06164  1.000 36.68226  ? 78  PRO A O    1 
ATOM   1241 C CB   . PRO A 1 78  ? 37.00924 5.70392  0.44745   1.000 38.59677  ? 78  PRO A CB   1 
ATOM   1242 C CG   . PRO A 1 78  ? 36.06662 5.90680  1.58803   1.000 39.28616  ? 78  PRO A CG   1 
ATOM   1243 C CD   . PRO A 1 78  ? 35.46468 7.26917  1.37698   1.000 41.45689  ? 78  PRO A CD   1 
ATOM   1244 H HA   . PRO A 1 78  ? 38.41369 7.20801  0.62321   1.000 48.77060  ? 78  PRO A HA   1 
ATOM   1245 H HB2  . PRO A 1 78  ? 36.54398 5.36406  -0.33289  1.000 46.31613  ? 78  PRO A HB2  1 
ATOM   1246 H HB3  . PRO A 1 78  ? 37.72890 5.10170  0.69304   1.000 46.31613  ? 78  PRO A HB3  1 
ATOM   1247 H HG2  . PRO A 1 78  ? 35.38079 5.22100  1.57312   1.000 47.14340  ? 78  PRO A HG2  1 
ATOM   1248 H HG3  . PRO A 1 78  ? 36.55321 5.87121  2.42640   1.000 47.14340  ? 78  PRO A HG3  1 
ATOM   1249 H HD2  . PRO A 1 78  ? 34.67186 7.21565  0.82067   1.000 49.74827  ? 78  PRO A HD2  1 
ATOM   1250 H HD3  . PRO A 1 78  ? 35.24748 7.68749  2.22475   1.000 49.74827  ? 78  PRO A HD3  1 
ATOM   1251 N N    . GLU A 1 79  ? 39.00518 7.22102  -1.78485  1.000 35.99514  ? 79  GLU A N    1 
ATOM   1252 C CA   . GLU A 1 79  ? 39.31212 7.50032  -3.18105  1.000 47.74574  ? 79  GLU A CA   1 
ATOM   1253 C C    . GLU A 1 79  ? 38.50894 6.58064  -4.09360  1.000 45.22901  ? 79  GLU A C    1 
ATOM   1254 O O    . GLU A 1 79  ? 38.42471 5.37060  -3.86076  1.000 44.15499  ? 79  GLU A O    1 
ATOM   1255 C CB   . GLU A 1 79  ? 40.81016 7.34128  -3.43500  1.000 44.73784  ? 79  GLU A CB   1 
ATOM   1256 C CG   . GLU A 1 79  ? 41.67169 8.42314  -2.78822  1.000 45.26361  ? 79  GLU A CG   1 
ATOM   1257 C CD   . GLU A 1 79  ? 41.88738 8.20318  -1.30030  1.000 51.22014  ? 79  GLU A CD   1 
ATOM   1258 O OE1  . GLU A 1 79  ? 41.36431 7.20796  -0.75693  1.000 49.16501  ? 79  GLU A OE1  1 
ATOM   1259 O OE2  . GLU A 1 79  ? 42.58697 9.02490  -0.67202  1.000 52.60782  ? 79  GLU A OE2  1 
ATOM   1260 H H    . GLU A 1 79  ? 39.68164 6.98648  -1.30841  1.000 43.19417  ? 79  GLU A H    1 
ATOM   1261 H HA   . GLU A 1 79  ? 39.07185 8.41699  -3.38813  1.000 57.29489  ? 79  GLU A HA   1 
ATOM   1262 H HB2  . GLU A 1 79  ? 41.09601 6.48536  -3.07919  1.000 53.68541  ? 79  GLU A HB2  1 
ATOM   1263 H HB3  . GLU A 1 79  ? 40.96768 7.37219  -4.39163  1.000 53.68541  ? 79  GLU A HB3  1 
ATOM   1264 H HG2  . GLU A 1 79  ? 42.54132 8.43167  -3.21782  1.000 54.31633  ? 79  GLU A HG2  1 
ATOM   1265 H HG3  . GLU A 1 79  ? 41.23655 9.28244  -2.90291  1.000 54.31633  ? 79  GLU A HG3  1 
ATOM   1266 N N    . GLY A 1 80  ? 37.91305 7.16175  -5.13004  1.000 45.03376  ? 80  GLY A N    1 
ATOM   1267 C CA   . GLY A 1 80  ? 37.05044 6.43098  -6.02925  1.000 46.34049  ? 80  GLY A CA   1 
ATOM   1268 C C    . GLY A 1 80  ? 35.59960 6.35323  -5.60680  1.000 42.78125  ? 80  GLY A C    1 
ATOM   1269 O O    . GLY A 1 80  ? 34.80918 5.68788  -6.28752  1.000 44.79794  ? 80  GLY A O    1 
ATOM   1270 H H    . GLY A 1 80  ? 37.99864 7.99351  -5.33115  1.000 54.04052  ? 80  GLY A H    1 
ATOM   1271 H HA2  . GLY A 1 80  ? 37.08119 6.85554  -6.90087  1.000 55.60859  ? 80  GLY A HA2  1 
ATOM   1272 H HA3  . GLY A 1 80  ? 37.38341 5.52335  -6.10816  1.000 55.60859  ? 80  GLY A HA3  1 
ATOM   1273 N N    . THR A 1 81  ? 35.22248 7.00677  -4.51175  1.000 39.44654  ? 81  THR A N    1 
ATOM   1274 C CA   . THR A 1 81  ? 33.84149 6.98919  -4.04889  1.000 41.83341  ? 81  THR A CA   1 
ATOM   1275 C C    . THR A 1 81  ? 32.99934 7.94888  -4.88034  1.000 44.77450  ? 81  THR A C    1 
ATOM   1276 O O    . THR A 1 81  ? 33.35216 9.12198  -5.03458  1.000 41.50882  ? 81  THR A O    1 
ATOM   1277 C CB   . THR A 1 81  ? 33.77170 7.37727  -2.57156  1.000 36.98311  ? 81  THR A CB   1 
ATOM   1278 O OG1  . THR A 1 81  ? 34.60063 6.49653  -1.80290  1.000 47.41198  ? 81  THR A OG1  1 
ATOM   1279 C CG2  . THR A 1 81  ? 32.33954 7.30675  -2.05717  1.000 42.91243  ? 81  THR A CG2  1 
ATOM   1280 H H    . THR A 1 81  ? 35.75157 7.47029  -4.01697  1.000 47.33585  ? 81  THR A H    1 
ATOM   1281 H HA   . THR A 1 81  ? 33.48003 6.09469  -4.14944  1.000 50.20009  ? 81  THR A HA   1 
ATOM   1282 H HB   . THR A 1 81  ? 34.08374 8.28955  -2.46544  1.000 44.37973  ? 81  THR A HB   1 
ATOM   1283 H HG1  . THR A 1 81  ? 35.38398 6.50172  -2.10612  1.000 56.89437  ? 81  THR A HG1  1 
ATOM   1284 H HG21 . THR A 1 81  ? 32.33060 7.37788  -1.08982  1.000 51.49492  ? 81  THR A HG21 1 
ATOM   1285 H HG22 . THR A 1 81  ? 31.81659 8.03312  -2.43108  1.000 51.49492  ? 81  THR A HG22 1 
ATOM   1286 H HG23 . THR A 1 81  ? 31.93575 6.46318  -2.31454  1.000 51.49492  ? 81  THR A HG23 1 
ATOM   1287 N N    . VAL A 1 82  ? 31.88857 7.45342  -5.41710  1.000 46.02921  ? 82  VAL A N    1 
ATOM   1288 C CA   . VAL A 1 82  ? 30.97430 8.30099  -6.17514  1.000 44.40797  ? 82  VAL A CA   1 
ATOM   1289 C C    . VAL A 1 82  ? 30.05575 9.00866  -5.18911  1.000 41.97686  ? 82  VAL A C    1 
ATOM   1290 O O    . VAL A 1 82  ? 29.27620 8.36646  -4.47764  1.000 47.89469  ? 82  VAL A O    1 
ATOM   1291 C CB   . VAL A 1 82  ? 30.16917 7.49098  -7.19901  1.000 48.83002  ? 82  VAL A CB   1 
ATOM   1292 C CG1  . VAL A 1 82  ? 29.03448 8.33994  -7.76525  1.000 49.51775  ? 82  VAL A CG1  1 
ATOM   1293 C CG2  . VAL A 1 82  ? 31.07410 7.00731  -8.32376  1.000 49.40777  ? 82  VAL A CG2  1 
ATOM   1294 H H    . VAL A 1 82  ? 31.64261 6.63157  -5.35655  1.000 55.23505  ? 82  VAL A H    1 
ATOM   1295 H HA   . VAL A 1 82  ? 31.48552 8.96696  -6.66097  1.000 53.28956  ? 82  VAL A HA   1 
ATOM   1296 H HB   . VAL A 1 82  ? 29.78738 6.71571  -6.75846  1.000 58.59602  ? 82  VAL A HB   1 
ATOM   1297 H HG11 . VAL A 1 82  ? 29.28653 9.27547  -7.71882  1.000 59.42130  ? 82  VAL A HG11 1 
ATOM   1298 H HG12 . VAL A 1 82  ? 28.87923 8.08461  -8.68807  1.000 59.42130  ? 82  VAL A HG12 1 
ATOM   1299 H HG13 . VAL A 1 82  ? 28.23325 8.18679  -7.24039  1.000 59.42130  ? 82  VAL A HG13 1 
ATOM   1300 H HG21 . VAL A 1 82  ? 30.55115 6.47401  -8.94264  1.000 59.28933  ? 82  VAL A HG21 1 
ATOM   1301 H HG22 . VAL A 1 82  ? 31.44620 7.77663  -8.78267  1.000 59.28933  ? 82  VAL A HG22 1 
ATOM   1302 H HG23 . VAL A 1 82  ? 31.78807 6.47033  -7.94588  1.000 59.28933  ? 82  VAL A HG23 1 
ATOM   1303 N N    . VAL A 1 83  ? 30.15793 10.33153 -5.13929  1.000 39.80301  ? 83  VAL A N    1 
ATOM   1304 C CA   . VAL A 1 83  ? 29.36528 11.14436 -4.23461  1.000 41.72063  ? 83  VAL A CA   1 
ATOM   1305 C C    . VAL A 1 83  ? 28.41675 12.00067 -5.06519  1.000 45.22333  ? 83  VAL A C    1 
ATOM   1306 O O    . VAL A 1 83  ? 28.47171 12.01908 -6.29498  1.000 47.72712  ? 83  VAL A O    1 
ATOM   1307 C CB   . VAL A 1 83  ? 30.24738 12.02181 -3.32708  1.000 41.84968  ? 83  VAL A CB   1 
ATOM   1308 C CG1  . VAL A 1 83  ? 31.23380 11.16141 -2.55540  1.000 39.70155  ? 83  VAL A CG1  1 
ATOM   1309 C CG2  . VAL A 1 83  ? 30.97257 13.07368 -4.15750  1.000 47.48933  ? 83  VAL A CG2  1 
ATOM   1310 H H    . VAL A 1 83  ? 30.69305 10.78959 -5.63267  1.000 47.76361  ? 83  VAL A H    1 
ATOM   1311 H HA   . VAL A 1 83  ? 28.83749 10.56213 -3.66597  1.000 50.06476  ? 83  VAL A HA   1 
ATOM   1312 H HB   . VAL A 1 83  ? 29.68676 12.48143 -2.68260  1.000 50.21961  ? 83  VAL A HB   1 
ATOM   1313 H HG11 . VAL A 1 83  ? 30.91127 10.24672 -2.54115  1.000 47.64186  ? 83  VAL A HG11 1 
ATOM   1314 H HG12 . VAL A 1 83  ? 32.09790 11.20066 -2.99437  1.000 47.64186  ? 83  VAL A HG12 1 
ATOM   1315 H HG13 . VAL A 1 83  ? 31.30728 11.50040 -1.64954  1.000 47.64186  ? 83  VAL A HG13 1 
ATOM   1316 H HG21 . VAL A 1 83  ? 31.09272 12.73658 -5.05906  1.000 56.98720  ? 83  VAL A HG21 1 
ATOM   1317 H HG22 . VAL A 1 83  ? 30.43986 13.88411 -4.17564  1.000 56.98720  ? 83  VAL A HG22 1 
ATOM   1318 H HG23 . VAL A 1 83  ? 31.83600 13.25436 -3.75409  1.000 56.98720  ? 83  VAL A HG23 1 
ATOM   1319 N N    . THR A 1 84  ? 27.53959 12.72291 -4.37571  1.000 42.69595  ? 84  THR A N    1 
ATOM   1320 C CA   . THR A 1 84  ? 26.61981 13.65530 -5.01393  1.000 45.89234  ? 84  THR A CA   1 
ATOM   1321 C C    . THR A 1 84  ? 26.86716 15.05042 -4.46257  1.000 44.60185  ? 84  THR A C    1 
ATOM   1322 O O    . THR A 1 84  ? 26.78636 15.26977 -3.24858  1.000 38.66615  ? 84  THR A O    1 
ATOM   1323 C CB   . THR A 1 84  ? 25.16075 13.24534 -4.79586  1.000 49.96254  ? 84  THR A CB   1 
ATOM   1324 O OG1  . THR A 1 84  ? 24.95822 12.89337 -3.42218  1.000 60.83162  ? 84  THR A OG1  1 
ATOM   1325 C CG2  . THR A 1 84  ? 24.80327 12.07308 -5.69857  1.000 45.67030  ? 84  THR A CG2  1 
ATOM   1326 H H    . THR A 1 84  ? 27.45781 12.68850 -3.52030  1.000 51.23514  ? 84  THR A H    1 
ATOM   1327 H HA   . THR A 1 84  ? 26.79332 13.66483 -5.96824  1.000 55.07081  ? 84  THR A HA   1 
ATOM   1328 H HB   . THR A 1 84  ? 24.57287 13.98456 -5.01688  1.000 59.95505  ? 84  THR A HB   1 
ATOM   1329 H HG1  . THR A 1 84  ? 25.15032 13.54447 -2.92744  1.000 72.99794  ? 84  THR A HG1  1 
ATOM   1330 H HG21 . THR A 1 84  ? 23.88521 11.80180 -5.54212  1.000 54.80436  ? 84  THR A HG21 1 
ATOM   1331 H HG22 . THR A 1 84  ? 24.90174 12.32881 -6.62906  1.000 54.80436  ? 84  THR A HG22 1 
ATOM   1332 H HG23 . THR A 1 84  ? 25.38910 11.32214 -5.51479  1.000 54.80436  ? 84  THR A HG23 1 
ATOM   1333 N N    . LEU A 1 85  ? 27.16746 15.98546 -5.35585  1.000 42.51665  ? 85  LEU A N    1 
ATOM   1334 C CA   . LEU A 1 85  ? 27.34938 17.38773 -5.00063  1.000 44.04556  ? 85  LEU A CA   1 
ATOM   1335 C C    . LEU A 1 85  ? 25.99033 18.07505 -5.07876  1.000 40.88890  ? 85  LEU A C    1 
ATOM   1336 O O    . LEU A 1 85  ? 25.45688 18.29237 -6.17159  1.000 37.65857  ? 85  LEU A O    1 
ATOM   1337 C CB   . LEU A 1 85  ? 28.37083 18.03143 -5.93223  1.000 40.54018  ? 85  LEU A CB   1 
ATOM   1338 C CG   . LEU A 1 85  ? 28.53932 19.54845 -5.89966  1.000 43.91010  ? 85  LEU A CG   1 
ATOM   1339 C CD1  . LEU A 1 85  ? 28.77025 20.04158 -4.48569  1.000 44.67595  ? 85  LEU A CD1  1 
ATOM   1340 C CD2  . LEU A 1 85  ? 29.69299 19.95793 -6.81461  1.000 46.61577  ? 85  LEU A CD2  1 
ATOM   1341 H H    . LEU A 1 85  ? 27.27375 15.82894 -6.19478  1.000 51.01998  ? 85  LEU A H    1 
ATOM   1342 H HA   . LEU A 1 85  ? 27.67735 17.47090 -4.09155  1.000 52.85468  ? 85  LEU A HA   1 
ATOM   1343 H HB2  . LEU A 1 85  ? 29.23845 17.65331 -5.71970  1.000 48.64822  ? 85  LEU A HB2  1 
ATOM   1344 H HB3  . LEU A 1 85  ? 28.12231 17.80136 -6.84118  1.000 48.64822  ? 85  LEU A HB3  1 
ATOM   1345 H HG   . LEU A 1 85  ? 27.72550 19.96816 -6.21973  1.000 52.69212  ? 85  LEU A HG   1 
ATOM   1346 H HD11 . LEU A 1 85  ? 28.87902 21.00534 -4.50116  1.000 53.61114  ? 85  LEU A HD11 1 
ATOM   1347 H HD12 . LEU A 1 85  ? 28.00483 19.80381 -3.93935  1.000 53.61114  ? 85  LEU A HD12 1 
ATOM   1348 H HD13 . LEU A 1 85  ? 29.57130 19.62392 -4.13246  1.000 53.61114  ? 85  LEU A HD13 1 
ATOM   1349 H HD21 . LEU A 1 85  ? 29.78163 20.92374 -6.79812  1.000 55.93892  ? 85  LEU A HD21 1 
ATOM   1350 H HD22 . LEU A 1 85  ? 30.51081 19.54522 -6.49565  1.000 55.93892  ? 85  LEU A HD22 1 
ATOM   1351 H HD23 . LEU A 1 85  ? 29.50169 19.65869 -7.71725  1.000 55.93892  ? 85  LEU A HD23 1 
ATOM   1352 N N    . LEU A 1 86  ? 25.42821 18.41123 -3.91813  1.000 33.81435  ? 86  LEU A N    1 
ATOM   1353 C CA   . LEU A 1 86  ? 24.07037 18.94722 -3.83311  1.000 40.89985  ? 86  LEU A CA   1 
ATOM   1354 C C    . LEU A 1 86  ? 24.10524 20.44482 -4.10275  1.000 37.19127  ? 86  LEU A C    1 
ATOM   1355 O O    . LEU A 1 86  ? 24.23022 21.26547 -3.19254  1.000 34.69655  ? 86  LEU A O    1 
ATOM   1356 C CB   . LEU A 1 86  ? 23.46077 18.65262 -2.46910  1.000 40.35039  ? 86  LEU A CB   1 
ATOM   1357 C CG   . LEU A 1 86  ? 23.37511 17.18643 -2.04894  1.000 45.48841  ? 86  LEU A CG   1 
ATOM   1358 C CD1  . LEU A 1 86  ? 22.81954 17.08990 -0.63647  1.000 42.63170  ? 86  LEU A CD1  1 
ATOM   1359 C CD2  . LEU A 1 86  ? 22.51873 16.39030 -3.01479  1.000 47.73473  ? 86  LEU A CD2  1 
ATOM   1360 H H    . LEU A 1 86  ? 25.81870 18.33701 -3.15550  1.000 40.57722  ? 86  LEU A H    1 
ATOM   1361 H HA   . LEU A 1 86  ? 23.52900 18.52761 -4.51995  1.000 49.07982  ? 86  LEU A HA   1 
ATOM   1362 H HB2  . LEU A 1 86  ? 23.99441 19.10798 -1.79920  1.000 48.42046  ? 86  LEU A HB2  1 
ATOM   1363 H HB3  . LEU A 1 86  ? 22.55556 19.00116 -2.46532  1.000 48.42046  ? 86  LEU A HB3  1 
ATOM   1364 H HG   . LEU A 1 86  ? 24.26403 16.79846 -2.06322  1.000 54.58609  ? 86  LEU A HG   1 
ATOM   1365 H HD11 . LEU A 1 86  ? 22.86633 16.16715 -0.34109  1.000 51.15804  ? 86  LEU A HD11 1 
ATOM   1366 H HD12 . LEU A 1 86  ? 23.34904 17.65228 -0.04973  1.000 51.15804  ? 86  LEU A HD12 1 
ATOM   1367 H HD13 . LEU A 1 86  ? 21.89718 17.39014 -0.63871  1.000 51.15804  ? 86  LEU A HD13 1 
ATOM   1368 H HD21 . LEU A 1 86  ? 22.52763 15.45732 -2.74952  1.000 57.28168  ? 86  LEU A HD21 1 
ATOM   1369 H HD22 . LEU A 1 86  ? 21.61163 16.73294 -2.98880  1.000 57.28168  ? 86  LEU A HD22 1 
ATOM   1370 H HD23 . LEU A 1 86  ? 22.88196 16.48332 -3.90939  1.000 57.28168  ? 86  LEU A HD23 1 
ATOM   1371 N N    . ILE A 1 87  ? 23.97185 20.80583 -5.37280  1.000 36.06232  ? 87  ILE A N    1 
ATOM   1372 C CA   . ILE A 1 87  ? 23.98413 22.20070 -5.78991  1.000 40.75541  ? 87  ILE A CA   1 
ATOM   1373 C C    . ILE A 1 87  ? 22.56424 22.74680 -5.71319  1.000 43.20827  ? 87  ILE A C    1 
ATOM   1374 O O    . ILE A 1 87  ? 21.64556 22.20136 -6.33419  1.000 41.47884  ? 87  ILE A O    1 
ATOM   1375 C CB   . ILE A 1 87  ? 24.54444 22.35434 -7.20906  1.000 39.15110  ? 87  ILE A CB   1 
ATOM   1376 C CG1  . ILE A 1 87  ? 25.96186 21.78677 -7.29791  1.000 44.31691  ? 87  ILE A CG1  1 
ATOM   1377 C CG2  . ILE A 1 87  ? 24.52557 23.81916 -7.62732  1.000 43.82409  ? 87  ILE A CG2  1 
ATOM   1378 C CD1  . ILE A 1 87  ? 27.03175 22.69306 -6.72825  1.000 42.14635  ? 87  ILE A CD1  1 
ATOM   1379 H H    . ILE A 1 87  ? 23.87114 20.25131 -6.02239  1.000 43.27479  ? 87  ILE A H    1 
ATOM   1380 H HA   . ILE A 1 87  ? 24.54290 22.70496 -5.17803  1.000 48.90650  ? 87  ILE A HA   1 
ATOM   1381 H HB   . ILE A 1 87  ? 23.97983 21.84956 -7.81512  1.000 46.98132  ? 87  ILE A HB   1 
ATOM   1382 H HG12 . ILE A 1 87  ? 25.99240 20.95106 -6.80642  1.000 53.18029  ? 87  ILE A HG12 1 
ATOM   1383 H HG13 . ILE A 1 87  ? 26.17526 21.63076 -8.23120  1.000 53.18029  ? 87  ILE A HG13 1 
ATOM   1384 H HG21 . ILE A 1 87  ? 23.61788 24.06931 -7.86060  1.000 52.58890  ? 87  ILE A HG21 1 
ATOM   1385 H HG22 . ILE A 1 87  ? 24.83879 24.36286 -6.88761  1.000 52.58890  ? 87  ILE A HG22 1 
ATOM   1386 H HG23 . ILE A 1 87  ? 25.10832 23.93623 -8.39387  1.000 52.58890  ? 87  ILE A HG23 1 
ATOM   1387 H HD11 . ILE A 1 87  ? 26.70093 23.09716 -5.91083  1.000 50.57562  ? 87  ILE A HD11 1 
ATOM   1388 H HD12 . ILE A 1 87  ? 27.82421 22.16641 -6.53970  1.000 50.57562  ? 87  ILE A HD12 1 
ATOM   1389 H HD13 . ILE A 1 87  ? 27.23984 23.38294 -7.37760  1.000 50.57562  ? 87  ILE A HD13 1 
ATOM   1390 N N    . LYS A 1 88  ? 22.38638 23.82416 -4.95460  1.000 40.21100  ? 88  LYS A N    1 
ATOM   1391 C CA   . LYS A 1 88  ? 21.18533 24.64352 -5.03310  1.000 37.29949  ? 88  LYS A CA   1 
ATOM   1392 C C    . LYS A 1 88  ? 21.49287 25.87262 -5.87687  1.000 39.78928  ? 88  LYS A C    1 
ATOM   1393 O O    . LYS A 1 88  ? 22.53411 26.51537 -5.68984  1.000 39.24446  ? 88  LYS A O    1 
ATOM   1394 C CB   . LYS A 1 88  ? 20.69193 25.07441 -3.65490  1.000 41.05935  ? 88  LYS A CB   1 
ATOM   1395 C CG   . LYS A 1 88  ? 19.83878 24.04235 -2.94662  1.000 46.69436  ? 88  LYS A CG   1 
ATOM   1396 C CD   . LYS A 1 88  ? 19.06493 24.66681 -1.79361  1.000 47.19468  ? 88  LYS A CD   1 
ATOM   1397 C CE   . LYS A 1 88  ? 18.16851 23.64144 -1.11853  1.000 43.94869  ? 88  LYS A CE   1 
ATOM   1398 N NZ   . LYS A 1 88  ? 17.58627 24.14435 0.15679   1.000 46.58148  ? 88  LYS A NZ   1 
ATOM   1399 H H    . LYS A 1 88  ? 22.95867 24.10425 -4.37699  1.000 48.25320  ? 88  LYS A H    1 
ATOM   1400 H HA   . LYS A 1 88  ? 20.47541 24.12818 -5.44702  1.000 44.75939  ? 88  LYS A HA   1 
ATOM   1401 H HB2  . LYS A 1 88  ? 21.46172 25.25478 -3.09296  1.000 49.27122  ? 88  LYS A HB2  1 
ATOM   1402 H HB3  . LYS A 1 88  ? 20.15826 25.87826 -3.75453  1.000 49.27122  ? 88  LYS A HB3  1 
ATOM   1403 H HG2  . LYS A 1 88  ? 19.20236 23.66460 -3.57365  1.000 56.03323  ? 88  LYS A HG2  1 
ATOM   1404 H HG3  . LYS A 1 88  ? 20.40829 23.34279 -2.58999  1.000 56.03323  ? 88  LYS A HG3  1 
ATOM   1405 H HD2  . LYS A 1 88  ? 19.68842 25.01024 -1.13466  1.000 56.63362  ? 88  LYS A HD2  1 
ATOM   1406 H HD3  . LYS A 1 88  ? 18.50836 25.38635 -2.13037  1.000 56.63362  ? 88  LYS A HD3  1 
ATOM   1407 H HE2  . LYS A 1 88  ? 17.43730 23.41754 -1.71527  1.000 52.73843  ? 88  LYS A HE2  1 
ATOM   1408 H HE3  . LYS A 1 88  ? 18.68892 22.84753 -0.91906  1.000 52.73843  ? 88  LYS A HE3  1 
ATOM   1409 H HZ1  . LYS A 1 88  ? 17.09301 24.86870 0.00145   1.000 55.89778  ? 88  LYS A HZ1  1 
ATOM   1410 H HZ2  . LYS A 1 88  ? 18.23695 24.35471 0.72640   1.000 55.89778  ? 88  LYS A HZ2  1 
ATOM   1411 H HZ3  . LYS A 1 88  ? 17.07185 23.51800 0.52443   1.000 55.89778  ? 88  LYS A HZ3  1 
ATOM   1412 N N    . ARG A 1 89  ? 20.59893 26.19145 -6.79630  1.000 39.14324  ? 89  ARG A N    1 
ATOM   1413 C CA   . ARG A 1 89  ? 20.71632 27.38868 -7.61004  1.000 36.48780  ? 89  ARG A CA   1 
ATOM   1414 C C    . ARG A 1 89  ? 19.83807 28.49445 -7.03656  1.000 38.54348  ? 89  ARG A C    1 
ATOM   1415 O O    . ARG A 1 89  ? 18.86945 28.24356 -6.31454  1.000 35.30101  ? 89  ARG A O    1 
ATOM   1416 C CB   . ARG A 1 89  ? 20.33948 27.09047 -9.06142  1.000 34.95571  ? 89  ARG A CB   1 
ATOM   1417 C CG   . ARG A 1 89  ? 21.40030 26.28093 -9.80367  1.000 46.50268  ? 89  ARG A CG   1 
ATOM   1418 C CD   . ARG A 1 89  ? 22.63866 27.12222 -10.10572 1.000 48.55869  ? 89  ARG A CD   1 
ATOM   1419 N NE   . ARG A 1 89  ? 23.86382 26.32996 -10.11577 1.000 47.87026  ? 89  ARG A NE   1 
ATOM   1420 C CZ   . ARG A 1 89  ? 24.29546 25.61807 -11.14886 1.000 51.52091  ? 89  ARG A CZ   1 
ATOM   1421 N NH1  . ARG A 1 89  ? 23.60557 25.54290 -12.27455 1.000 48.57535  ? 89  ARG A NH1  1 
ATOM   1422 N NH2  . ARG A 1 89  ? 25.44978 24.96391 -11.04903 1.000 51.06240  ? 89  ARG A NH2  1 
ATOM   1423 H H    . ARG A 1 89  ? 19.90090 25.72058 -6.97138  1.000 46.97189  ? 89  ARG A H    1 
ATOM   1424 H HA   . ARG A 1 89  ? 21.63365 27.70394 -7.60715  1.000 43.78536  ? 89  ARG A HA   1 
ATOM   1425 H HB2  . ARG A 1 89  ? 19.51344 26.58212 -9.07329  1.000 41.94686  ? 89  ARG A HB2  1 
ATOM   1426 H HB3  . ARG A 1 89  ? 20.21958 27.92935 -9.53344  1.000 41.94686  ? 89  ARG A HB3  1 
ATOM   1427 H HG2  . ARG A 1 89  ? 21.67028 25.52709 -9.25619  1.000 55.80321  ? 89  ARG A HG2  1 
ATOM   1428 H HG3  . ARG A 1 89  ? 21.03361 25.96578 -10.64457 1.000 55.80321  ? 89  ARG A HG3  1 
ATOM   1429 H HD2  . ARG A 1 89  ? 22.53837 27.53204 -10.97916 1.000 58.27043  ? 89  ARG A HD2  1 
ATOM   1430 H HD3  . ARG A 1 89  ? 22.72965 27.80813 -9.42590  1.000 58.27043  ? 89  ARG A HD3  1 
ATOM   1431 H HE   . ARG A 1 89  ? 24.34078 26.32398 -9.40018  1.000 57.44431  ? 89  ARG A HE   1 
ATOM   1432 H HH11 . ARG A 1 89  ? 22.85806 25.96148 -12.34953 1.000 58.29042  ? 89  ARG A HH11 1 
ATOM   1433 H HH12 . ARG A 1 89  ? 23.90442 25.07543 -12.93163 1.000 58.29042  ? 89  ARG A HH12 1 
ATOM   1434 H HH21 . ARG A 1 89  ? 25.90618 25.00570 -10.32133 1.000 61.27488  ? 89  ARG A HH21 1 
ATOM   1435 H HH22 . ARG A 1 89  ? 25.73948 24.49929 -11.71221 1.000 61.27488  ? 89  ARG A HH22 1 
ATOM   1436 N N    . SER A 1 90  ? 20.21036 29.73678 -7.35576  1.000 37.33805  ? 90  SER A N    1 
ATOM   1437 C CA   . SER A 1 90  ? 19.48919 30.89022 -6.82783  1.000 39.34245  ? 90  SER A CA   1 
ATOM   1438 C C    . SER A 1 90  ? 18.01215 30.83891 -7.18894  1.000 40.72188  ? 90  SER A C    1 
ATOM   1439 O O    . SER A 1 90  ? 17.16494 31.29569 -6.41217  1.000 46.86370  ? 90  SER A O    1 
ATOM   1440 C CB   . SER A 1 90  ? 20.12455 32.17810 -7.35267  1.000 36.10138  ? 90  SER A CB   1 
ATOM   1441 O OG   . SER A 1 90  ? 20.27481 32.13083 -8.76261  1.000 44.32214  ? 90  SER A OG   1 
ATOM   1442 H H    . SER A 1 90  ? 20.87015 29.93486 -7.87058  1.000 44.80566  ? 90  SER A H    1 
ATOM   1443 H HA   . SER A 1 90  ? 19.55705 30.89178 -5.86021  1.000 47.21094  ? 90  SER A HA   1 
ATOM   1444 H HB2  . SER A 1 90  ? 19.55465 32.92811 -7.12114  1.000 43.32166  ? 90  SER A HB2  1 
ATOM   1445 H HB3  . SER A 1 90  ? 20.99829 32.28735 -6.94581  1.000 43.32166  ? 90  SER A HB3  1 
ATOM   1446 H HG   . SER A 1 90  ? 20.81012 31.51903 -8.97413  1.000 53.18657  ? 90  SER A HG   1 
ATOM   1447 N N    . THR A 1 91  ? 17.68719 30.28070 -8.35623  1.000 39.01646  ? 91  THR A N    1 
ATOM   1448 C CA   . THR A 1 91  ? 16.29910 30.13573 -8.76985  1.000 41.22226  ? 91  THR A CA   1 
ATOM   1449 C C    . THR A 1 91  ? 15.48019 29.30120 -7.79739  1.000 39.36368  ? 91  THR A C    1 
ATOM   1450 O O    . THR A 1 91  ? 14.25189 29.44057 -7.76044  1.000 35.57713  ? 91  THR A O    1 
ATOM   1451 C CB   . THR A 1 91  ? 16.24065 29.47809 -10.14938 1.000 39.56971  ? 91  THR A CB   1 
ATOM   1452 O OG1  . THR A 1 91  ? 17.03444 28.28150 -10.13135 1.000 41.88995  ? 91  THR A OG1  1 
ATOM   1453 C CG2  . THR A 1 91  ? 16.76290 30.42043 -11.21947 1.000 40.07431  ? 91  THR A CG2  1 
ATOM   1454 H H    . THR A 1 91  ? 18.25551 29.97794 -8.92627  1.000 46.81975  ? 91  THR A H    1 
ATOM   1455 H HA   . THR A 1 91  ? 15.90392 31.02027 -8.81789  1.000 49.46671  ? 91  THR A HA   1 
ATOM   1456 H HB   . THR A 1 91  ? 15.32172 29.25909 -10.36963 1.000 47.48365  ? 91  THR A HB   1 
ATOM   1457 H HG1  . THR A 1 91  ? 17.02053 27.91608 -10.88758 1.000 50.26794  ? 91  THR A HG1  1 
ATOM   1458 H HG21 . THR A 1 91  ? 17.66883 30.69431 -11.00693 1.000 48.08917  ? 91  THR A HG21 1 
ATOM   1459 H HG22 . THR A 1 91  ? 16.76245 29.97612 -12.08173 1.000 48.08917  ? 91  THR A HG22 1 
ATOM   1460 H HG23 . THR A 1 91  ? 16.19971 31.20850 -11.27112 1.000 48.08917  ? 91  THR A HG23 1 
ATOM   1461 N N    . GLY A 1 92  ? 16.12919 28.44335 -7.01440  1.000 40.05511  ? 92  GLY A N    1 
ATOM   1462 C CA   . GLY A 1 92  ? 15.45687 27.40288 -6.27078  1.000 37.44413  ? 92  GLY A CA   1 
ATOM   1463 C C    . GLY A 1 92  ? 15.56813 26.03061 -6.89835  1.000 38.65885  ? 92  GLY A C    1 
ATOM   1464 O O    . GLY A 1 92  ? 15.24190 25.03539 -6.23939  1.000 41.27691  ? 92  GLY A O    1 
ATOM   1465 H H    . GLY A 1 92  ? 16.98148 28.45039 -6.89976  1.000 48.06613  ? 92  GLY A H    1 
ATOM   1466 H HA2  . GLY A 1 92  ? 15.83781 27.35691 -5.37990  1.000 44.93295  ? 92  GLY A HA2  1 
ATOM   1467 H HA3  . GLY A 1 92  ? 14.51526 27.62498 -6.20054  1.000 44.93295  ? 92  GLY A HA3  1 
ATOM   1468 N N    . GLU A 1 93  ? 16.02264 25.94953 -8.14726  1.000 43.11180  ? 93  GLU A N    1 
ATOM   1469 C CA   . GLU A 1 93  ? 16.21418 24.65967 -8.79582  1.000 41.18909  ? 93  GLU A CA   1 
ATOM   1470 C C    . GLU A 1 93  ? 17.24678 23.83731 -8.03686  1.000 43.54289  ? 93  GLU A C    1 
ATOM   1471 O O    . GLU A 1 93  ? 18.30174 24.34979 -7.64709  1.000 40.79965  ? 93  GLU A O    1 
ATOM   1472 C CB   . GLU A 1 93  ? 16.65963 24.85793 -10.24698 1.000 39.05859  ? 93  GLU A CB   1 
ATOM   1473 C CG   . GLU A 1 93  ? 16.68331 23.58181 -11.08864 1.000 53.41783  ? 93  GLU A CG   1 
ATOM   1474 C CD   . GLU A 1 93  ? 15.50624 23.48249 -12.04801 1.000 61.79213  ? 93  GLU A CD   1 
ATOM   1475 O OE1  . GLU A 1 93  ? 15.02762 24.53314 -12.52695 1.000 65.32728  ? 93  GLU A OE1  1 
ATOM   1476 O OE2  . GLU A 1 93  ? 15.05774 22.34994 -12.32577 1.000 69.56447  ? 93  GLU A OE2  1 
ATOM   1477 H H    . GLU A 1 93  ? 16.22648 26.62570 -8.63801  1.000 51.73416  ? 93  GLU A H    1 
ATOM   1478 H HA   . GLU A 1 93  ? 15.37441 24.17422 -8.80061  1.000 49.42691  ? 93  GLU A HA   1 
ATOM   1479 H HB2  . GLU A 1 93  ? 16.04894 25.47848 -10.67461 1.000 46.87031  ? 93  GLU A HB2  1 
ATOM   1480 H HB3  . GLU A 1 93  ? 17.55793 25.22392 -10.24619 1.000 46.87031  ? 93  GLU A HB3  1 
ATOM   1481 H HG2  . GLU A 1 93  ? 17.49909 23.56498 -11.61317 1.000 64.10140  ? 93  GLU A HG2  1 
ATOM   1482 H HG3  . GLU A 1 93  ? 16.65312 22.81340 -10.49743 1.000 64.10140  ? 93  GLU A HG3  1 
ATOM   1483 N N    . LEU A 1 94  ? 16.93617 22.56254 -7.82108  1.000 44.65681  ? 94  LEU A N    1 
ATOM   1484 C CA   . LEU A 1 94  ? 17.89871 21.61079 -7.28628  1.000 46.56988  ? 94  LEU A CA   1 
ATOM   1485 C C    . LEU A 1 94  ? 18.66615 20.99730 -8.45077  1.000 44.77832  ? 94  LEU A C    1 
ATOM   1486 O O    . LEU A 1 94  ? 18.06008 20.54805 -9.42947  1.000 49.49155  ? 94  LEU A O    1 
ATOM   1487 C CB   . LEU A 1 94  ? 17.20327 20.51561 -6.48200  1.000 47.09768  ? 94  LEU A CB   1 
ATOM   1488 C CG   . LEU A 1 94  ? 16.12023 20.94913 -5.49442  1.000 54.95568  ? 94  LEU A CG   1 
ATOM   1489 C CD1  . LEU A 1 94  ? 15.51448 19.72502 -4.81043  1.000 49.84469  ? 94  LEU A CD1  1 
ATOM   1490 C CD2  . LEU A 1 94  ? 16.66143 21.92575 -4.46330  1.000 52.82688  ? 94  LEU A CD2  1 
ATOM   1491 H H    . LEU A 1 94  ? 16.16265 22.22165 -7.97938  1.000 53.58817  ? 94  LEU A H    1 
ATOM   1492 H HA   . LEU A 1 94  ? 18.51570 22.06420 -6.69076  1.000 55.88386  ? 94  LEU A HA   1 
ATOM   1493 H HB2  . LEU A 1 94  ? 16.78387 19.90682 -7.11000  1.000 56.51722  ? 94  LEU A HB2  1 
ATOM   1494 H HB3  . LEU A 1 94  ? 17.88090 20.04815 -5.96897  1.000 56.51722  ? 94  LEU A HB3  1 
ATOM   1495 H HG   . LEU A 1 94  ? 15.42138 21.40998 -5.98444  1.000 65.94681  ? 94  LEU A HG   1 
ATOM   1496 H HD11 . LEU A 1 94  ? 14.82586 20.01685 -4.19275  1.000 59.81363  ? 94  LEU A HD11 1 
ATOM   1497 H HD12 . LEU A 1 94  ? 15.12909 19.14457 -5.48531  1.000 59.81363  ? 94  LEU A HD12 1 
ATOM   1498 H HD13 . LEU A 1 94  ? 16.21280 19.25439 -4.32901  1.000 59.81363  ? 94  LEU A HD13 1 
ATOM   1499 H HD21 . LEU A 1 94  ? 15.94309 22.18288 -3.86433  1.000 63.39226  ? 94  LEU A HD21 1 
ATOM   1500 H HD22 . LEU A 1 94  ? 17.37153 21.49481 -3.96237  1.000 63.39226  ? 94  LEU A HD22 1 
ATOM   1501 H HD23 . LEU A 1 94  ? 17.00703 22.70836 -4.92046  1.000 63.39226  ? 94  LEU A HD23 1 
ATOM   1502 N N    . MET A 1 95  ? 19.99282 20.98169 -8.34871  1.000 49.23258  ? 95  MET A N    1 
ATOM   1503 C CA   . MET A 1 95  ? 20.85987 20.46944 -9.40920  1.000 46.25682  ? 95  MET A CA   1 
ATOM   1504 C C    . MET A 1 95  ? 21.88250 19.51685 -8.80286  1.000 45.29312  ? 95  MET A C    1 
ATOM   1505 O O    . MET A 1 95  ? 23.07105 19.83918 -8.69103  1.000 47.23034  ? 95  MET A O    1 
ATOM   1506 C CB   . MET A 1 95  ? 21.54749 21.61222 -10.15762 1.000 50.02039  ? 95  MET A CB   1 
ATOM   1507 C CG   . MET A 1 95  ? 21.79456 21.30446 -11.62516 1.000 62.12418  ? 95  MET A CG   1 
ATOM   1508 S SD   . MET A 1 95  ? 23.00714 22.38440 -12.40206 1.000 71.69868  ? 95  MET A SD   1 
ATOM   1509 C CE   . MET A 1 95  ? 23.28633 21.50326 -13.93554 1.000 73.42070  ? 95  MET A CE   1 
ATOM   1510 H H    . MET A 1 95  ? 20.42279 21.26812 -7.66120  1.000 59.07910  ? 95  MET A H    1 
ATOM   1511 H HA   . MET A 1 95  ? 20.31562 19.97958 -10.04539 1.000 55.50818  ? 95  MET A HA   1 
ATOM   1512 H HB2  . MET A 1 95  ? 20.98635 22.40191 -10.10870 1.000 60.02446  ? 95  MET A HB2  1 
ATOM   1513 H HB3  . MET A 1 95  ? 22.40558 21.78865 -9.74115  1.000 60.02446  ? 95  MET A HB3  1 
ATOM   1514 H HG2  . MET A 1 95  ? 22.11832 20.39335 -11.70240 1.000 74.54902  ? 95  MET A HG2  1 
ATOM   1515 H HG3  . MET A 1 95  ? 20.95953 21.40196 -12.10900 1.000 74.54902  ? 95  MET A HG3  1 
ATOM   1516 H HE1  . MET A 1 95  ? 23.93555 21.99087 -14.46626 1.000 88.10484  ? 95  MET A HE1  1 
ATOM   1517 H HE2  . MET A 1 95  ? 23.62343 20.61648 -13.73335 1.000 88.10484  ? 95  MET A HE2  1 
ATOM   1518 H HE3  . MET A 1 95  ? 22.44774 21.43620 -14.41842 1.000 88.10484  ? 95  MET A HE3  1 
ATOM   1519 N N    . PRO A 1 96  ? 21.44772 18.32401 -8.39841  1.000 43.33206  ? 96  PRO A N    1 
ATOM   1520 C CA   . PRO A 1 96  ? 22.39816 17.32161 -7.88739  1.000 41.08550  ? 96  PRO A CA   1 
ATOM   1521 C C    . PRO A 1 96  ? 23.33183 16.85280 -8.99404  1.000 42.45640  ? 96  PRO A C    1 
ATOM   1522 O O    . PRO A 1 96  ? 22.88603 16.37742 -10.04030 1.000 44.64205  ? 96  PRO A O    1 
ATOM   1523 C CB   . PRO A 1 96  ? 21.48993 16.19017 -7.38748  1.000 43.41201  ? 96  PRO A CB   1 
ATOM   1524 C CG   . PRO A 1 96  ? 20.20757 16.36355 -8.15032  1.000 41.78532  ? 96  PRO A CG   1 
ATOM   1525 C CD   . PRO A 1 96  ? 20.05292 17.84601 -8.35918  1.000 43.58371  ? 96  PRO A CD   1 
ATOM   1526 H HA   . PRO A 1 96  ? 22.91623 17.67796 -7.14880  1.000 49.30259  ? 96  PRO A HA   1 
ATOM   1527 H HB2  . PRO A 1 96  ? 21.89573 15.33037 -7.57976  1.000 52.09442  ? 96  PRO A HB2  1 
ATOM   1528 H HB3  . PRO A 1 96  ? 21.34221 16.28131 -6.43314  1.000 52.09442  ? 96  PRO A HB3  1 
ATOM   1529 H HG2  . PRO A 1 96  ? 20.26734 15.90091 -9.00079  1.000 50.14239  ? 96  PRO A HG2  1 
ATOM   1530 H HG3  . PRO A 1 96  ? 19.46777 16.01037 -7.63180  1.000 50.14239  ? 96  PRO A HG3  1 
ATOM   1531 H HD2  . PRO A 1 96  ? 19.59949 18.03224 -9.19621  1.000 52.30045  ? 96  PRO A HD2  1 
ATOM   1532 H HD3  . PRO A 1 96  ? 19.56887 18.25076 -7.62245  1.000 52.30045  ? 96  PRO A HD3  1 
ATOM   1533 N N    . LEU A 1 97  ? 24.63288 16.99838 -8.76121  1.000 40.73857  ? 97  LEU A N    1 
ATOM   1534 C CA   . LEU A 1 97  ? 25.65946 16.56045 -9.69527  1.000 36.44838  ? 97  LEU A CA   1 
ATOM   1535 C C    . LEU A 1 97  ? 26.42162 15.38984 -9.08871  1.000 38.08795  ? 97  LEU A C    1 
ATOM   1536 O O    . LEU A 1 97  ? 26.84798 15.45461 -7.93062  1.000 43.38766  ? 97  LEU A O    1 
ATOM   1537 C CB   . LEU A 1 97  ? 26.62653 17.69740 -10.02477 1.000 40.74780  ? 97  LEU A CB   1 
ATOM   1538 C CG   . LEU A 1 97  ? 26.03324 18.99784 -10.56746 1.000 45.53480  ? 97  LEU A CG   1 
ATOM   1539 C CD1  . LEU A 1 97  ? 27.13640 20.03837 -10.69456 1.000 44.58386  ? 97  LEU A CD1  1 
ATOM   1540 C CD2  . LEU A 1 97  ? 25.33779 18.78366 -11.90247 1.000 48.55346  ? 97  LEU A CD2  1 
ATOM   1541 H H    . LEU A 1 97  ? 24.95199 17.35840 -8.04836  1.000 48.88628  ? 97  LEU A H    1 
ATOM   1542 H HA   . LEU A 1 97  ? 25.24131 16.26724 -10.51994 1.000 43.73806  ? 97  LEU A HA   1 
ATOM   1543 H HB2  . LEU A 1 97  ? 27.10375 17.92510 -9.21156  1.000 48.89735  ? 97  LEU A HB2  1 
ATOM   1544 H HB3  . LEU A 1 97  ? 27.24843 17.37229 -10.69442 1.000 48.89735  ? 97  LEU A HB3  1 
ATOM   1545 H HG   . LEU A 1 97  ? 25.35839 19.32151 -9.95044  1.000 54.64176  ? 97  LEU A HG   1 
ATOM   1546 H HD11 . LEU A 1 97  ? 27.53053 20.18907 -9.82114  1.000 53.50063  ? 97  LEU A HD11 1 
ATOM   1547 H HD12 . LEU A 1 97  ? 27.81082 19.71010 -11.30961 1.000 53.50063  ? 97  LEU A HD12 1 
ATOM   1548 H HD13 . LEU A 1 97  ? 26.75463 20.86376 -11.03204 1.000 53.50063  ? 97  LEU A HD13 1 
ATOM   1549 H HD21 . LEU A 1 97  ? 24.60847 18.15568 -11.78146 1.000 58.26415  ? 97  LEU A HD21 1 
ATOM   1550 H HD22 . LEU A 1 97  ? 24.99350 19.63343 -12.21911 1.000 58.26415  ? 97  LEU A HD22 1 
ATOM   1551 H HD23 . LEU A 1 97  ? 25.97805 18.42842 -12.53868 1.000 58.26415  ? 97  LEU A HD23 1 
ATOM   1552 N N    . ALA A 1 98  ? 26.58739 14.32498 -9.86757  1.000 37.82048  ? 98  ALA A N    1 
ATOM   1553 C CA   . ALA A 1 98  ? 27.37165 13.17989 -9.42807  1.000 40.46926  ? 98  ALA A CA   1 
ATOM   1554 C C    . ALA A 1 98  ? 28.85086 13.43351 -9.68404  1.000 44.59556  ? 98  ALA A C    1 
ATOM   1555 O O    . ALA A 1 98  ? 29.22850 14.01913 -10.70273 1.000 46.68473  ? 98  ALA A O    1 
ATOM   1556 C CB   . ALA A 1 98  ? 26.92335 11.91163 -10.15276 1.000 39.50296  ? 98  ALA A CB   1 
ATOM   1557 H H    . ALA A 1 98  ? 26.25467 14.24231 -10.65628 1.000 45.38458  ? 98  ALA A H    1 
ATOM   1558 H HA   . ALA A 1 98  ? 27.24121 13.04067 -8.47702  1.000 48.56311  ? 98  ALA A HA   1 
ATOM   1559 H HB1  . ALA A 1 98  ? 27.46539 11.16645 -9.84978  1.000 47.40355  ? 98  ALA A HB1  1 
ATOM   1560 H HB2  . ALA A 1 98  ? 25.98948 11.74538 -9.94995  1.000 47.40355  ? 98  ALA A HB2  1 
ATOM   1561 H HB3  . ALA A 1 98  ? 27.03723 12.03668 -11.10790 1.000 47.40355  ? 98  ALA A HB3  1 
ATOM   1562 N N    . ALA A 1 99  ? 29.68926 12.99477 -8.75026  1.000 46.08285  ? 99  ALA A N    1 
ATOM   1563 C CA   . ALA A 1 99  ? 31.13052 13.14061 -8.88393  1.000 45.32872  ? 99  ALA A CA   1 
ATOM   1564 C C    . ALA A 1 99  ? 31.81758 11.92649 -8.28284  1.000 48.08067  ? 99  ALA A C    1 
ATOM   1565 O O    . ALA A 1 99  ? 31.34705 11.36726 -7.28807  1.000 47.12789  ? 99  ALA A O    1 
ATOM   1566 C CB   . ALA A 1 99  ? 31.63383 14.41718 -8.19601  1.000 37.02213  ? 99  ALA A CB   1 
ATOM   1567 H H    . ALA A 1 99  ? 29.44291 12.60572 -8.02394  1.000 55.29942  ? 99  ALA A H    1 
ATOM   1568 H HA   . ALA A 1 99  ? 31.36389 13.18947 -9.82417  1.000 54.39447  ? 99  ALA A HA   1 
ATOM   1569 H HB1  . ALA A 1 99  ? 32.59390 14.48381 -8.31742  1.000 44.42656  ? 99  ALA A HB1  1 
ATOM   1570 H HB2  . ALA A 1 99  ? 31.19582 15.18491 -8.59556  1.000 44.42656  ? 99  ALA A HB2  1 
ATOM   1571 H HB3  . ALA A 1 99  ? 31.42243 14.37073 -7.25047  1.000 44.42656  ? 99  ALA A HB3  1 
ATOM   1572 N N    . ARG A 1 100 ? 32.92357 11.51587 -8.89853  1.000 46.02138  ? 100 ARG A N    1 
ATOM   1573 C CA   . ARG A 1 100 ? 33.79402 10.49286 -8.33696  1.000 45.86758  ? 100 ARG A CA   1 
ATOM   1574 C C    . ARG A 1 100 ? 34.97677 11.18602 -7.67386  1.000 39.46456  ? 100 ARG A C    1 
ATOM   1575 O O    . ARG A 1 100 ? 35.76789 11.85556 -8.34719  1.000 41.49099  ? 100 ARG A O    1 
ATOM   1576 C CB   . ARG A 1 100 ? 34.29027 9.51271  -9.39658  1.000 44.51446  ? 100 ARG A CB   1 
ATOM   1577 C CG   . ARG A 1 100 ? 35.08710 8.35374  -8.80070  1.000 49.88887  ? 100 ARG A CG   1 
ATOM   1578 C CD   . ARG A 1 100 ? 35.69441 7.48242  -9.88142  1.000 49.45110  ? 100 ARG A CD   1 
ATOM   1579 N NE   . ARG A 1 100 ? 34.72677 7.23598  -10.94200 1.000 60.15789  ? 100 ARG A NE   1 
ATOM   1580 C CZ   . ARG A 1 100 ? 33.80471 6.28432  -10.91191 1.000 71.59069  ? 100 ARG A CZ   1 
ATOM   1581 N NH1  . ARG A 1 100 ? 33.73542 5.41918  -9.91342  1.000 69.06142  ? 100 ARG A NH1  1 
ATOM   1582 N NH2  . ARG A 1 100 ? 32.92693 6.20212  -11.90722 1.000 68.74318  ? 100 ARG A NH2  1 
ATOM   1583 H H    . ARG A 1 100 ? 33.19321 11.82186 -9.65567  1.000 55.22566  ? 100 ARG A H    1 
ATOM   1584 H HA   . ARG A 1 100 ? 33.29659 9.98423  -7.67760  1.000 55.04109  ? 100 ARG A HA   1 
ATOM   1585 H HB2  . ARG A 1 100 ? 33.52680 9.14237  -9.86654  1.000 53.41736  ? 100 ARG A HB2  1 
ATOM   1586 H HB3  . ARG A 1 100 ? 34.86573 9.98471  -10.01865 1.000 53.41736  ? 100 ARG A HB3  1 
ATOM   1587 H HG2  . ARG A 1 100 ? 35.80632 8.70626  -8.25357  1.000 59.86665  ? 100 ARG A HG2  1 
ATOM   1588 H HG3  . ARG A 1 100 ? 34.49852 7.80348  -8.26063  1.000 59.86665  ? 100 ARG A HG3  1 
ATOM   1589 H HD2  . ARG A 1 100 ? 36.46548 7.92954  -10.26409 1.000 59.34132  ? 100 ARG A HD2  1 
ATOM   1590 H HD3  . ARG A 1 100 ? 35.95985 6.63056  -9.50094  1.000 59.34132  ? 100 ARG A HD3  1 
ATOM   1591 H HE   . ARG A 1 100 ? 34.75578 7.74321  -11.63589 1.000 72.18947  ? 100 ARG A HE   1 
ATOM   1592 H HH11 . ARG A 1 100 ? 34.29689 5.46651  -9.26371  1.000 82.87370  ? 100 ARG A HH11 1 
ATOM   1593 H HH12 . ARG A 1 100 ? 33.12891 4.80948  -9.91405  1.000 82.87370  ? 100 ARG A HH12 1 
ATOM   1594 H HH21 . ARG A 1 100 ? 32.96225 6.76201  -12.55904 1.000 82.49182  ? 100 ARG A HH21 1 
ATOM   1595 H HH22 . ARG A 1 100 ? 32.32387 5.58905  -11.89917 1.000 82.49182  ? 100 ARG A HH22 1 
ATOM   1596 N N    . MET A 1 101 ? 35.09765 11.01777 -6.36509  1.000 39.41181  ? 101 MET A N    1 
ATOM   1597 C CA   . MET A 1 101 ? 36.14844 11.67746 -5.61060  1.000 37.52606  ? 101 MET A CA   1 
ATOM   1598 C C    . MET A 1 101 ? 37.47362 10.95799 -5.81056  1.000 35.81620  ? 101 MET A C    1 
ATOM   1599 O O    . MET A 1 101 ? 37.51877 9.75768  -6.09796  1.000 36.82757  ? 101 MET A O    1 
ATOM   1600 C CB   . MET A 1 101 ? 35.77262 11.72495 -4.13461  1.000 38.58113  ? 101 MET A CB   1 
ATOM   1601 C CG   . MET A 1 101 ? 34.42827 12.39018 -3.90128  1.000 33.16536  ? 101 MET A CG   1 
ATOM   1602 S SD   . MET A 1 101 ? 34.33175 14.02244 -4.67079  1.000 36.42631  ? 101 MET A SD   1 
ATOM   1603 C CE   . MET A 1 101 ? 35.72528 14.82881 -3.88420  1.000 38.15882  ? 101 MET A CE   1 
ATOM   1604 H H    . MET A 1 101 ? 34.58002 10.52333 -5.88846  1.000 47.29417  ? 101 MET A H    1 
ATOM   1605 H HA   . MET A 1 101 ? 36.25291 12.59274 -5.91432  1.000 45.03127  ? 101 MET A HA   1 
ATOM   1606 H HB2  . MET A 1 101 ? 35.72522 10.81939 -3.79021  1.000 46.29735  ? 101 MET A HB2  1 
ATOM   1607 H HB3  . MET A 1 101 ? 36.44656 12.22863 -3.65189  1.000 46.29735  ? 101 MET A HB3  1 
ATOM   1608 H HG2  . MET A 1 101 ? 33.72863 11.83539 -4.28024  1.000 39.79843  ? 101 MET A HG2  1 
ATOM   1609 H HG3  . MET A 1 101 ? 34.28717 12.49670 -2.94753  1.000 39.79843  ? 101 MET A HG3  1 
ATOM   1610 H HE1  . MET A 1 101 ? 35.73889 15.76265 -4.14622  1.000 45.79058  ? 101 MET A HE1  1 
ATOM   1611 H HE2  . MET A 1 101 ? 35.62975 14.75670 -2.92162  1.000 45.79058  ? 101 MET A HE2  1 
ATOM   1612 H HE3  . MET A 1 101 ? 36.54399 14.39342 -4.16890  1.000 45.79058  ? 101 MET A HE3  1 
ATOM   1613 N N    . GLY A 1 102 ? 38.55882 11.71392 -5.66707  1.000 40.29246  ? 102 GLY A N    1 
ATOM   1614 C CA   . GLY A 1 102 ? 39.88143 11.19891 -5.94736  1.000 37.26622  ? 102 GLY A CA   1 
ATOM   1615 C C    . GLY A 1 102 ? 40.90469 11.59804 -4.90810  1.000 36.56723  ? 102 GLY A C    1 
ATOM   1616 O O    . GLY A 1 102 ? 40.67026 11.46307 -3.70380  1.000 39.95550  ? 102 GLY A O    1 
ATOM   1617 H H    . GLY A 1 102 ? 38.54922 12.53344 -5.40651  1.000 48.35096  ? 102 GLY A H    1 
ATOM   1618 H HA2  . GLY A 1 102 ? 39.84530 10.23015 -5.98063  1.000 44.71946  ? 102 GLY A HA2  1 
ATOM   1619 H HA3  . GLY A 1 102 ? 40.17747 11.53364 -6.80829  1.000 44.71946  ? 102 GLY A HA3  1 
ATOM   1620 N N    . THR A 1 103 ? 42.03913 12.11272 -5.37056  1.000 42.09334  ? 103 THR A N    1 
ATOM   1621 C CA   . THR A 1 103 ? 43.16157 12.38992 -4.48884  1.000 35.98215  ? 103 THR A CA   1 
ATOM   1622 C C    . THR A 1 103 ? 42.79220 13.40248 -3.41173  1.000 38.08451  ? 103 THR A C    1 
ATOM   1623 O O    . THR A 1 103 ? 42.31108 14.49892 -3.71049  1.000 36.71205  ? 103 THR A O    1 
ATOM   1624 C CB   . THR A 1 103 ? 44.33842 12.91424 -5.31621  1.000 37.33660  ? 103 THR A CB   1 
ATOM   1625 O OG1  . THR A 1 103 ? 44.76509 11.90358 -6.23876  1.000 44.41548  ? 103 THR A OG1  1 
ATOM   1626 C CG2  . THR A 1 103 ? 45.50449 13.32344 -4.42142  1.000 37.49984  ? 103 THR A CG2  1 
ATOM   1627 H H    . THR A 1 103 ? 42.18361 12.31087 -6.19485  1.000 50.51201  ? 103 THR A H    1 
ATOM   1628 H HA   . THR A 1 103 ? 43.42091 11.56913 -4.04169  1.000 43.17858  ? 103 THR A HA   1 
ATOM   1629 H HB   . THR A 1 103 ? 44.05656 13.70133 -5.80808  1.000 44.80392  ? 103 THR A HB   1 
ATOM   1630 H HG1  . THR A 1 103 ? 45.35815 12.21125 -6.74790  1.000 53.29858  ? 103 THR A HG1  1 
ATOM   1631 H HG21 . THR A 1 103 ? 45.68891 12.62331 -3.77589  1.000 44.99981  ? 103 THR A HG21 1 
ATOM   1632 H HG22 . THR A 1 103 ? 46.29815 13.47336 -4.95857  1.000 44.99981  ? 103 THR A HG22 1 
ATOM   1633 H HG23 . THR A 1 103 ? 45.28709 14.14057 -3.94610  1.000 44.99981  ? 103 THR A HG23 1 
ATOM   1634 N N    . HIS A 1 104 ? 43.01168 13.02469 -2.15315  1.000 38.28485  ? 104 HIS A N    1 
ATOM   1635 C CA   . HIS A 1 104 ? 43.09336 13.99302 -1.06854  1.000 35.50810  ? 104 HIS A CA   1 
ATOM   1636 C C    . HIS A 1 104 ? 44.43028 14.71279 -1.17344  1.000 32.93898  ? 104 HIS A C    1 
ATOM   1637 O O    . HIS A 1 104 ? 45.44782 14.09282 -1.49476  1.000 34.85886  ? 104 HIS A O    1 
ATOM   1638 C CB   . HIS A 1 104 ? 42.99793 13.31454 0.29777   1.000 33.58940  ? 104 HIS A CB   1 
ATOM   1639 C CG   . HIS A 1 104 ? 41.72529 12.55956 0.52377   1.000 45.42125  ? 104 HIS A CG   1 
ATOM   1640 N ND1  . HIS A 1 104 ? 40.86142 12.85301 1.55727   1.000 39.41456  ? 104 HIS A ND1  1 
ATOM   1641 C CD2  . HIS A 1 104 ? 41.18247 11.50766 -0.13343  1.000 43.73883  ? 104 HIS A CD2  1 
ATOM   1642 C CE1  . HIS A 1 104 ? 39.83565 12.02128 1.52031   1.000 43.38393  ? 104 HIS A CE1  1 
ATOM   1643 N NE2  . HIS A 1 104 ? 40.00581 11.19455 0.50373   1.000 44.60797  ? 104 HIS A NE2  1 
ATOM   1644 H H    . HIS A 1 104 ? 43.11689 12.20875 -1.90261  1.000 45.94183  ? 104 HIS A H    1 
ATOM   1645 H HA   . HIS A 1 104 ? 42.35688 14.62113 -1.13163  1.000 42.60972  ? 104 HIS A HA   1 
ATOM   1646 H HB2  . HIS A 1 104 ? 43.73152 12.68568 0.38317   1.000 40.30728  ? 104 HIS A HB2  1 
ATOM   1647 H HB3  . HIS A 1 104 ? 43.06211 13.99465 0.98641   1.000 40.30728  ? 104 HIS A HB3  1 
ATOM   1648 H HD2  . HIS A 1 104 ? 41.53911 11.07753 -0.87686  1.000 52.48660  ? 104 HIS A HD2  1 
ATOM   1649 H HE1  . HIS A 1 104 ? 39.11616 12.01820 2.10957   1.000 52.06072  ? 104 HIS A HE1  1 
ATOM   1650 H HE2  . HIS A 1 104 ? 39.46762 10.56306 0.27754   1.000 53.52956  ? 104 HIS A HE2  1 
ATOM   1651 N N    . ALA A 1 105 ? 44.44259 16.01206 -0.89065  1.000 33.97786  ? 105 ALA A N    1 
ATOM   1652 C CA   . ALA A 1 105 ? 45.71300 16.72056 -0.96520  1.000 36.74456  ? 105 ALA A CA   1 
ATOM   1653 C C    . ALA A 1 105 ? 45.58707 18.13512 -0.42861  1.000 37.46692  ? 105 ALA A C    1 
ATOM   1654 O O    . ALA A 1 105 ? 44.49765 18.71117 -0.37383  1.000 37.08982  ? 105 ALA A O    1 
ATOM   1655 C CB   . ALA A 1 105 ? 46.23726 16.76795 -2.40870  1.000 35.48114  ? 105 ALA A CB   1 
ATOM   1656 H H    . ALA A 1 105 ? 43.75940 16.48255 -0.66376  1.000 40.77343  ? 105 ALA A H    1 
ATOM   1657 H HA   . ALA A 1 105 ? 46.34037 16.25338 -0.39158  1.000 44.09347  ? 105 ALA A HA   1 
ATOM   1658 H HB1  . ALA A 1 105 ? 46.42004 15.86362 -2.70815  1.000 42.57737  ? 105 ALA A HB1  1 
ATOM   1659 H HB2  . ALA A 1 105 ? 45.56372 17.17450 -2.97612  1.000 42.57737  ? 105 ALA A HB2  1 
ATOM   1660 H HB3  . ALA A 1 105 ? 47.05128 17.29496 -2.43190  1.000 42.57737  ? 105 ALA A HB3  1 
ATOM   1661 N N    . THR A 1 106 ? 46.73338 18.67803 -0.02526  1.000 36.03990  ? 106 THR A N    1 
ATOM   1662 C CA   . THR A 1 106 ? 46.90159 20.11495 0.12660   1.000 37.59605  ? 106 THR A CA   1 
ATOM   1663 C C    . THR A 1 106 ? 47.20125 20.68797 -1.25189  1.000 39.22667  ? 106 THR A C    1 
ATOM   1664 O O    . THR A 1 106 ? 48.23033 20.35972 -1.85292  1.000 39.79793  ? 106 THR A O    1 
ATOM   1665 C CB   . THR A 1 106 ? 48.02914 20.42769 1.10222   1.000 44.63170  ? 106 THR A CB   1 
ATOM   1666 O OG1  . THR A 1 106 ? 47.84345 19.66644 2.30128   1.000 55.63480  ? 106 THR A OG1  1 
ATOM   1667 C CG2  . THR A 1 106 ? 48.04339 21.90815 1.44226   1.000 47.53078  ? 106 THR A CG2  1 
ATOM   1668 H H    . THR A 1 106 ? 47.43852 18.22573 0.16917   1.000 43.24788  ? 106 THR A H    1 
ATOM   1669 H HA   . THR A 1 106 ? 46.09421 20.51703 0.48348   1.000 45.11526  ? 106 THR A HA   1 
ATOM   1670 H HB   . THR A 1 106 ? 48.88180 20.19916 0.70017   1.000 53.55804  ? 106 THR A HB   1 
ATOM   1671 H HG1  . THR A 1 106 ? 48.40095 19.90526 2.88244   1.000 66.76175  ? 106 THR A HG1  1 
ATOM   1672 H HG21 . THR A 1 106 ? 47.19266 22.16789 1.82917   1.000 57.03694  ? 106 THR A HG21 1 
ATOM   1673 H HG22 . THR A 1 106 ? 48.74962 22.09521 2.08034   1.000 57.03694  ? 106 THR A HG22 1 
ATOM   1674 H HG23 . THR A 1 106 ? 48.19721 22.43134 0.64007   1.000 57.03694  ? 106 THR A HG23 1 
ATOM   1675 N N    . MET A 1 107 ? 46.30077 21.51843 -1.76198  1.000 34.41619  ? 107 MET A N    1 
ATOM   1676 C CA   . MET A 1 107 ? 46.37088 21.99122 -3.13421  1.000 37.84498  ? 107 MET A CA   1 
ATOM   1677 C C    . MET A 1 107 ? 46.61824 23.49102 -3.17192  1.000 36.48768  ? 107 MET A C    1 
ATOM   1678 O O    . MET A 1 107 ? 46.19533 24.23208 -2.28096  1.000 39.36560  ? 107 MET A O    1 
ATOM   1679 C CB   . MET A 1 107 ? 45.07505 21.67263 -3.88367  1.000 39.08426  ? 107 MET A CB   1 
ATOM   1680 C CG   . MET A 1 107 ? 44.72576 20.19817 -3.91998  1.000 47.07554  ? 107 MET A CG   1 
ATOM   1681 S SD   . MET A 1 107 ? 43.02784 19.92824 -4.45058  1.000 43.91127  ? 107 MET A SD   1 
ATOM   1682 C CE   . MET A 1 107 ? 42.16480 20.10644 -2.89576  1.000 40.48115  ? 107 MET A CE   1 
ATOM   1683 H H    . MET A 1 107 ? 45.62843 21.82644 -1.32303  1.000 41.29942  ? 107 MET A H    1 
ATOM   1684 H HA   . MET A 1 107 ? 47.10532 21.54321 -3.58230  1.000 45.41398  ? 107 MET A HA   1 
ATOM   1685 H HB2  . MET A 1 107 ? 44.34309 22.13798 -3.44940  1.000 46.90111  ? 107 MET A HB2  1 
ATOM   1686 H HB3  . MET A 1 107 ? 45.16412 21.97675 -4.80045  1.000 46.90111  ? 107 MET A HB3  1 
ATOM   1687 H HG2  . MET A 1 107 ? 45.31496 19.74504 -4.54321  1.000 56.49065  ? 107 MET A HG2  1 
ATOM   1688 H HG3  . MET A 1 107 ? 44.83029 19.82263 -3.03175  1.000 56.49065  ? 107 MET A HG3  1 
ATOM   1689 H HE1  . MET A 1 107 ? 41.21560 19.97288 -3.04433  1.000 48.57738  ? 107 MET A HE1  1 
ATOM   1690 H HE2  . MET A 1 107 ? 42.49845 19.44316 -2.27154  1.000 48.57738  ? 107 MET A HE2  1 
ATOM   1691 H HE3  . MET A 1 107 ? 42.32286 20.99774 -2.54718  1.000 48.57738  ? 107 MET A HE3  1 
ATOM   1692 N N    . LYS A 1 108 ? 47.30896 23.92981 -4.21643  1.000 37.55896  ? 108 LYS A N    1 
ATOM   1693 C CA   . LYS A 1 108 ? 47.48087 25.34691 -4.50265  1.000 40.60532  ? 108 LYS A CA   1 
ATOM   1694 C C    . LYS A 1 108 ? 46.44971 25.74920 -5.54847  1.000 36.67751  ? 108 LYS A C    1 
ATOM   1695 O O    . LYS A 1 108 ? 46.47382 25.24756 -6.67714  1.000 38.72266  ? 108 LYS A O    1 
ATOM   1696 C CB   . LYS A 1 108 ? 48.89764 25.64425 -4.98563  1.000 39.90854  ? 108 LYS A CB   1 
ATOM   1697 C CG   . LYS A 1 108 ? 49.93412 25.54083 -3.87920  1.000 54.12506  ? 108 LYS A CG   1 
ATOM   1698 C CD   . LYS A 1 108 ? 50.56211 26.88935 -3.54549  1.000 67.23941  ? 108 LYS A CD   1 
ATOM   1699 C CE   . LYS A 1 108 ? 51.64529 27.26030 -4.54979  1.000 79.44819  ? 108 LYS A CE   1 
ATOM   1700 N NZ   . LYS A 1 108 ? 52.85735 27.83232 -3.89336  1.000 87.65172  ? 108 LYS A NZ   1 
ATOM   1701 H H    . LYS A 1 108 ? 47.69562 23.41422 -4.78587  1.000 45.07075  ? 108 LYS A H    1 
ATOM   1702 H HA   . LYS A 1 108 ? 47.33117 25.86805 -3.69835  1.000 48.72638  ? 108 LYS A HA   1 
ATOM   1703 H HB2  . LYS A 1 108 ? 49.13433 25.00792 -5.67842  1.000 47.89024  ? 108 LYS A HB2  1 
ATOM   1704 H HB3  . LYS A 1 108 ? 48.92671 26.54670 -5.34010  1.000 47.89024  ? 108 LYS A HB3  1 
ATOM   1705 H HG2  . LYS A 1 108 ? 49.50968 25.19927 -3.07665  1.000 64.95007  ? 108 LYS A HG2  1 
ATOM   1706 H HG3  . LYS A 1 108 ? 50.64182 24.94048 -4.16141  1.000 64.95007  ? 108 LYS A HG3  1 
ATOM   1707 H HD2  . LYS A 1 108 ? 49.87813 27.57684 -3.56602  1.000 80.68729  ? 108 LYS A HD2  1 
ATOM   1708 H HD3  . LYS A 1 108 ? 50.96433 26.84775 -2.66380  1.000 80.68729  ? 108 LYS A HD3  1 
ATOM   1709 H HE2  . LYS A 1 108 ? 51.91317 26.46508 -5.03638  1.000 95.33783  ? 108 LYS A HE2  1 
ATOM   1710 H HE3  . LYS A 1 108 ? 51.29461 27.92326 -5.16493  1.000 95.33783  ? 108 LYS A HE3  1 
ATOM   1711 H HZ1  . LYS A 1 108 ? 53.46690 28.03993 -4.50773  1.000 105.18206 ? 108 LYS A HZ1  1 
ATOM   1712 H HZ2  . LYS A 1 108 ? 52.64039 28.56784 -3.44165  1.000 105.18206 ? 108 LYS A HZ2  1 
ATOM   1713 H HZ3  . LYS A 1 108 ? 53.20643 27.23922 -3.32903  1.000 105.18206 ? 108 LYS A HZ3  1 
ATOM   1714 N N    . ILE A 1 109 ? 45.53874 26.63678 -5.16491  1.000 38.30436  ? 109 ILE A N    1 
ATOM   1715 C CA   . ILE A 1 109 ? 44.48802 27.13175 -6.04557  1.000 42.73916  ? 109 ILE A CA   1 
ATOM   1716 C C    . ILE A 1 109 ? 44.60614 28.64834 -6.07112  1.000 36.56662  ? 109 ILE A C    1 
ATOM   1717 O O    . ILE A 1 109 ? 44.32908 29.31715 -5.06694  1.000 37.70734  ? 109 ILE A O    1 
ATOM   1718 C CB   . ILE A 1 109 ? 43.09313 26.68668 -5.58600  1.000 38.14501  ? 109 ILE A CB   1 
ATOM   1719 C CG1  . ILE A 1 109 ? 42.98655 25.15975 -5.64505  1.000 44.07344  ? 109 ILE A CG1  1 
ATOM   1720 C CG2  . ILE A 1 109 ? 42.01258 27.32552 -6.45157  1.000 43.66117  ? 109 ILE A CG2  1 
ATOM   1721 C CD1  . ILE A 1 109 ? 41.73278 24.59854 -5.01277  1.000 48.37468  ? 109 ILE A CD1  1 
ATOM   1722 H H    . ILE A 1 109 ? 45.50859 26.97661 -4.37547  1.000 45.96523  ? 109 ILE A H    1 
ATOM   1723 H HA   . ILE A 1 109 ? 44.62986 26.79670 -6.94475  1.000 51.28699  ? 109 ILE A HA   1 
ATOM   1724 H HB   . ILE A 1 109 ? 42.96399 26.97804 -4.66985  1.000 45.77402  ? 109 ILE A HB   1 
ATOM   1725 H HG12 . ILE A 1 109 ? 42.99506 24.88436 -6.57510  1.000 52.88812  ? 109 ILE A HG12 1 
ATOM   1726 H HG13 . ILE A 1 109 ? 43.74676 24.77791 -5.17903  1.000 52.88812  ? 109 ILE A HG13 1 
ATOM   1727 H HG21 . ILE A 1 109 ? 41.14294 27.02674 -6.14277  1.000 52.39341  ? 109 ILE A HG21 1 
ATOM   1728 H HG22 . ILE A 1 109 ? 42.07687 28.29043 -6.37597  1.000 52.39341  ? 109 ILE A HG22 1 
ATOM   1729 H HG23 . ILE A 1 109 ? 42.14655 27.05633 -7.37379  1.000 52.39341  ? 109 ILE A HG23 1 
ATOM   1730 H HD11 . ILE A 1 109 ? 41.75095 23.63106 -5.08021  1.000 58.04961  ? 109 ILE A HD11 1 
ATOM   1731 H HD12 . ILE A 1 109 ? 41.70296 24.86463 -4.08046  1.000 58.04961  ? 109 ILE A HD12 1 
ATOM   1732 H HD13 . ILE A 1 109 ? 40.95894 24.94833 -5.48150  1.000 58.04961  ? 109 ILE A HD13 1 
ATOM   1733 N N    . GLN A 1 110 ? 45.01894 29.19231 -7.21342  1.000 44.67392  ? 110 GLN A N    1 
ATOM   1734 C CA   . GLN A 1 110 ? 45.17614 30.63497 -7.37855  1.000 43.40182  ? 110 GLN A CA   1 
ATOM   1735 C C    . GLN A 1 110 ? 46.04018 31.21562 -6.26023  1.000 45.38341  ? 110 GLN A C    1 
ATOM   1736 O O    . GLN A 1 110 ? 45.66741 32.17330 -5.57850  1.000 50.36321  ? 110 GLN A O    1 
ATOM   1737 C CB   . GLN A 1 110 ? 43.80982 31.32287 -7.44332  1.000 43.35452  ? 110 GLN A CB   1 
ATOM   1738 C CG   . GLN A 1 110 ? 43.02363 30.97369 -8.71063  1.000 44.32350  ? 110 GLN A CG   1 
ATOM   1739 C CD   . GLN A 1 110 ? 41.71870 31.74535 -8.83923  1.000 51.45729  ? 110 GLN A CD   1 
ATOM   1740 O OE1  . GLN A 1 110 ? 41.22658 32.32072 -7.87298  1.000 57.93150  ? 110 GLN A OE1  1 
ATOM   1741 N NE2  . GLN A 1 110 ? 41.15287 31.75518 -10.04726 1.000 60.19706  ? 110 GLN A NE2  1 
ATOM   1742 H H    . GLN A 1 110 ? 45.21707 28.73996 -7.91750  1.000 53.60870  ? 110 GLN A H    1 
ATOM   1743 H HA   . GLN A 1 110 ? 45.63364 30.80602 -8.21661  1.000 52.08219  ? 110 GLN A HA   1 
ATOM   1744 H HB2  . GLN A 1 110 ? 43.28184 31.04678 -6.67787  1.000 52.02543  ? 110 GLN A HB2  1 
ATOM   1745 H HB3  . GLN A 1 110 ? 43.94021 32.28393 -7.42715  1.000 52.02543  ? 110 GLN A HB3  1 
ATOM   1746 H HG2  . GLN A 1 110 ? 43.56923 31.17983 -9.48570  1.000 53.18820  ? 110 GLN A HG2  1 
ATOM   1747 H HG3  . GLN A 1 110 ? 42.81016 30.02757 -8.69734  1.000 53.18820  ? 110 GLN A HG3  1 
ATOM   1748 H HE21 . GLN A 1 110 ? 41.52685 31.33948 -10.70066 1.000 72.23648  ? 110 GLN A HE21 1 
ATOM   1749 H HE22 . GLN A 1 110 ? 40.41411 32.17722 -10.17264 1.000 72.23648  ? 110 GLN A HE22 1 
ATOM   1750 N N    . GLY A 1 111 ? 47.20932 30.60602 -6.06612  1.000 44.82265  ? 111 GLY A N    1 
ATOM   1751 C CA   . GLY A 1 111 ? 48.17681 31.08516 -5.10026  1.000 48.27914  ? 111 GLY A CA   1 
ATOM   1752 C C    . GLY A 1 111 ? 47.91222 30.65697 -3.67170  1.000 50.19294  ? 111 GLY A C    1 
ATOM   1753 O O    . GLY A 1 111 ? 48.84670 30.54848 -2.87194  1.000 54.54519  ? 111 GLY A O    1 
ATOM   1754 H H    . GLY A 1 111 ? 47.46375 29.90287 -6.49091  1.000 53.78717  ? 111 GLY A H    1 
ATOM   1755 H HA2  . GLY A 1 111 ? 49.05483 30.75680 -5.34957  1.000 57.93497  ? 111 GLY A HA2  1 
ATOM   1756 H HA3  . GLY A 1 111 ? 48.18449 32.05489 -5.12169  1.000 57.93497  ? 111 GLY A HA3  1 
ATOM   1757 N N    . ALA A 1 112 ? 46.65035 30.41969 -3.33218  1.000 44.32835  ? 112 ALA A N    1 
ATOM   1758 C CA   . ALA A 1 112 ? 46.27713 30.04111 -1.97778  1.000 46.41079  ? 112 ALA A CA   1 
ATOM   1759 C C    . ALA A 1 112 ? 46.35977 28.52769 -1.80015  1.000 42.02251  ? 112 ALA A C    1 
ATOM   1760 O O    . ALA A 1 112 ? 46.28019 27.75874 -2.76095  1.000 40.10919  ? 112 ALA A O    1 
ATOM   1761 C CB   . ALA A 1 112 ? 44.86634 30.53399 -1.64991  1.000 36.95670  ? 112 ALA A CB   1 
ATOM   1762 H H    . ALA A 1 112 ? 45.98568 30.47228 -3.87536  1.000 53.19403  ? 112 ALA A H    1 
ATOM   1763 H HA   . ALA A 1 112 ? 46.89227 30.45196 -1.35032  1.000 55.69295  ? 112 ALA A HA   1 
ATOM   1764 H HB1  . ALA A 1 112 ? 44.25346 30.21192 -2.32929  1.000 44.34804  ? 112 ALA A HB1  1 
ATOM   1765 H HB2  . ALA A 1 112 ? 44.60620 30.19135 -0.78053  1.000 44.34804  ? 112 ALA A HB2  1 
ATOM   1766 H HB3  . ALA A 1 112 ? 44.86575 31.50390 -1.63690  1.000 44.34804  ? 112 ALA A HB3  1 
ATOM   1767 N N    . THR A 1 113 ? 46.52920 28.10732 -0.54781  1.000 42.55709  ? 113 THR A N    1 
ATOM   1768 C CA   . THR A 1 113 ? 46.60590 26.69562 -0.19374  1.000 40.46820  ? 113 THR A CA   1 
ATOM   1769 C C    . THR A 1 113 ? 45.24877 26.24078 0.32640   1.000 40.99275  ? 113 THR A C    1 
ATOM   1770 O O    . THR A 1 113 ? 44.64107 26.91702 1.16393   1.000 47.92205  ? 113 THR A O    1 
ATOM   1771 C CB   . THR A 1 113 ? 47.68834 26.44164 0.85730   1.000 43.80298  ? 113 THR A CB   1 
ATOM   1772 O OG1  . THR A 1 113 ? 47.24546 26.90407 2.13871   1.000 59.27243  ? 113 THR A OG1  1 
ATOM   1773 C CG2  . THR A 1 113 ? 48.97300 27.16156 0.47695   1.000 38.91542  ? 113 THR A CG2  1 
ATOM   1774 H H    . THR A 1 113 ? 46.60379 28.63446 0.12758   1.000 51.06850  ? 113 THR A H    1 
ATOM   1775 H HA   . THR A 1 113 ? 46.83179 26.17627 -0.98124  1.000 48.56184  ? 113 THR A HA   1 
ATOM   1776 H HB   . THR A 1 113 ? 47.86952 25.49011 0.90890   1.000 52.56358  ? 113 THR A HB   1 
ATOM   1777 H HG1  . THR A 1 113 ? 47.81844 26.71942 2.72454   1.000 71.12692  ? 113 THR A HG1  1 
ATOM   1778 H HG21 . THR A 1 113 ? 49.69583 26.88038 1.05949   1.000 46.69851  ? 113 THR A HG21 1 
ATOM   1779 H HG22 . THR A 1 113 ? 49.20982 26.95504 -0.44075  1.000 46.69851  ? 113 THR A HG22 1 
ATOM   1780 H HG23 . THR A 1 113 ? 48.85402 28.12037 0.56321   1.000 46.69851  ? 113 THR A HG23 1 
ATOM   1781 N N    . VAL A 1 114 ? 44.77852 25.09966 -0.17339  1.000 38.65610  ? 114 VAL A N    1 
ATOM   1782 C CA   . VAL A 1 114 ? 43.43918 24.59797 0.11180   1.000 32.48283  ? 114 VAL A CA   1 
ATOM   1783 C C    . VAL A 1 114 ? 43.55537 23.13588 0.51703   1.000 31.78182  ? 114 VAL A C    1 
ATOM   1784 O O    . VAL A 1 114 ? 44.11502 22.32309 -0.22915  1.000 32.67913  ? 114 VAL A O    1 
ATOM   1785 C CB   . VAL A 1 114 ? 42.50189 24.74450 -1.10181  1.000 40.41998  ? 114 VAL A CB   1 
ATOM   1786 C CG1  . VAL A 1 114 ? 41.11841 24.17338 -0.79351  1.000 39.86691  ? 114 VAL A CG1  1 
ATOM   1787 C CG2  . VAL A 1 114 ? 42.40380 26.20308 -1.53243  1.000 44.34693  ? 114 VAL A CG2  1 
ATOM   1788 H H    . VAL A 1 114 ? 45.23049 24.58587 -0.69431  1.000 46.38732  ? 114 VAL A H    1 
ATOM   1789 H HA   . VAL A 1 114 ? 43.06449 25.09263 0.85734   1.000 38.97940  ? 114 VAL A HA   1 
ATOM   1790 H HB   . VAL A 1 114 ? 42.87264 24.23825 -1.84150  1.000 48.50397  ? 114 VAL A HB   1 
ATOM   1791 H HG11 . VAL A 1 114 ? 40.50805 24.42289 -1.50491  1.000 47.84029  ? 114 VAL A HG11 1 
ATOM   1792 H HG12 . VAL A 1 114 ? 41.18139 23.20717 -0.73541  1.000 47.84029  ? 114 VAL A HG12 1 
ATOM   1793 H HG13 . VAL A 1 114 ? 40.80807 24.53600 0.05095   1.000 47.84029  ? 114 VAL A HG13 1 
ATOM   1794 H HG21 . VAL A 1 114 ? 41.73299 26.28239 -2.22859  1.000 53.21632  ? 114 VAL A HG21 1 
ATOM   1795 H HG22 . VAL A 1 114 ? 42.15110 26.74214 -0.76663  1.000 53.21632  ? 114 VAL A HG22 1 
ATOM   1796 H HG23 . VAL A 1 114 ? 43.26631 26.49145 -1.86979  1.000 53.21632  ? 114 VAL A HG23 1 
ATOM   1797 N N    . GLY A 1 115 ? 43.03113 22.80244 1.69176   1.000 27.48981  ? 115 GLY A N    1 
ATOM   1798 C CA   . GLY A 1 115 ? 42.93609 21.41613 2.10071   1.000 30.85643  ? 115 GLY A CA   1 
ATOM   1799 C C    . GLY A 1 115 ? 41.64328 20.80062 1.60996   1.000 34.94081  ? 115 GLY A C    1 
ATOM   1800 O O    . GLY A 1 115 ? 40.56137 21.31568 1.90677   1.000 32.69526  ? 115 GLY A O    1 
ATOM   1801 H H    . GLY A 1 115 ? 42.72469 23.36382 2.26668   1.000 32.98778  ? 115 GLY A H    1 
ATOM   1802 H HA2  . GLY A 1 115 ? 43.68072 20.91466 1.73335   1.000 37.02772  ? 115 GLY A HA2  1 
ATOM   1803 H HA3  . GLY A 1 115 ? 42.96290 21.35776 3.06858   1.000 37.02772  ? 115 GLY A HA3  1 
ATOM   1804 N N    . GLY A 1 116 ? 41.72851 19.71637 0.85132   1.000 30.81446  ? 116 GLY A N    1 
ATOM   1805 C CA   . GLY A 1 116 ? 40.52234 19.12058 0.31538   1.000 40.29515  ? 116 GLY A CA   1 
ATOM   1806 C C    . GLY A 1 116 ? 40.80162 17.90310 -0.53111  1.000 35.44454  ? 116 GLY A C    1 
ATOM   1807 O O    . GLY A 1 116 ? 41.84404 17.25682 -0.40539  1.000 35.45060  ? 116 GLY A O    1 
ATOM   1808 H H    . GLY A 1 116 ? 42.45924 19.31630 0.63785   1.000 36.97735  ? 116 GLY A H    1 
ATOM   1809 H HA2  . GLY A 1 116 ? 39.94335 18.85577 1.04718   1.000 48.35418  ? 116 GLY A HA2  1 
ATOM   1810 H HA3  . GLY A 1 116 ? 40.05942 19.77279 -0.23346  1.000 48.35418  ? 116 GLY A HA3  1 
ATOM   1811 N N    . GLN A 1 117 ? 39.83957 17.60148 -1.40086  1.000 36.52521  ? 117 GLN A N    1 
ATOM   1812 C CA   . GLN A 1 117 ? 39.85954 16.39535 -2.21412  1.000 35.17813  ? 117 GLN A CA   1 
ATOM   1813 C C    . GLN A 1 117 ? 39.43449 16.74448 -3.62818  1.000 35.33962  ? 117 GLN A C    1 
ATOM   1814 O O    . GLN A 1 117 ? 38.38211 17.35838 -3.82947  1.000 38.80705  ? 117 GLN A O    1 
ATOM   1815 C CB   . GLN A 1 117 ? 38.92324 15.32703 -1.63673  1.000 37.16641  ? 117 GLN A CB   1 
ATOM   1816 C CG   . GLN A 1 117 ? 39.06867 13.95835 -2.27805  1.000 39.85981  ? 117 GLN A CG   1 
ATOM   1817 C CD   . GLN A 1 117 ? 38.18899 12.90896 -1.62167  1.000 40.29324  ? 117 GLN A CD   1 
ATOM   1818 O OE1  . GLN A 1 117 ? 37.32220 13.22651 -0.80630  1.000 38.25405  ? 117 GLN A OE1  1 
ATOM   1819 N NE2  . GLN A 1 117 ? 38.40938 11.64938 -1.97740  1.000 37.31611  ? 117 GLN A NE2  1 
ATOM   1820 H H    . GLN A 1 117 ? 39.14850 18.09433 -1.53912  1.000 43.83025  ? 117 GLN A H    1 
ATOM   1821 H HA   . GLN A 1 117 ? 40.76049 16.03701 -2.24236  1.000 42.21375  ? 117 GLN A HA   1 
ATOM   1822 H HB2  . GLN A 1 117 ? 39.11061 15.22962 -0.68999  1.000 44.59970  ? 117 GLN A HB2  1 
ATOM   1823 H HB3  . GLN A 1 117 ? 38.00633 15.61620 -1.76542  1.000 44.59970  ? 117 GLN A HB3  1 
ATOM   1824 H HG2  . GLN A 1 117 ? 38.81775 14.01861 -3.21309  1.000 47.83177  ? 117 GLN A HG2  1 
ATOM   1825 H HG3  . GLN A 1 117 ? 39.99110 13.66862 -2.20010  1.000 47.83177  ? 117 GLN A HG3  1 
ATOM   1826 H HE21 . GLN A 1 117 ? 39.02349 11.46565 -2.55074  1.000 44.77933  ? 117 GLN A HE21 1 
ATOM   1827 H HE22 . GLN A 1 117 ? 37.93809 11.01698 -1.63456  1.000 44.77933  ? 117 GLN A HE22 1 
ATOM   1828 N N    . MET A 1 118 ? 40.25201 16.35679 -4.59951  1.000 37.33522  ? 118 MET A N    1 
ATOM   1829 C CA   . MET A 1 118 ? 39.85830 16.49507 -5.99199  1.000 37.83266  ? 118 MET A CA   1 
ATOM   1830 C C    . MET A 1 118 ? 38.71675 15.54063 -6.31475  1.000 41.96388  ? 118 MET A C    1 
ATOM   1831 O O    . MET A 1 118 ? 38.64568 14.42355 -5.79047  1.000 40.38671  ? 118 MET A O    1 
ATOM   1832 C CB   . MET A 1 118 ? 41.04235 16.21679 -6.91411  1.000 40.68294  ? 118 MET A CB   1 
ATOM   1833 C CG   . MET A 1 118 ? 41.90330 17.43001 -7.22129  1.000 46.23879  ? 118 MET A CG   1 
ATOM   1834 S SD   . MET A 1 118 ? 43.55785 16.98280 -7.79073  1.000 49.52207  ? 118 MET A SD   1 
ATOM   1835 C CE   . MET A 1 118 ? 43.17977 15.68192 -8.95998  1.000 47.77887  ? 118 MET A CE   1 
ATOM   1836 H H    . MET A 1 118 ? 41.03163 16.01434 -4.47899  1.000 44.80226  ? 118 MET A H    1 
ATOM   1837 H HA   . MET A 1 118 ? 39.56897 17.40758 -6.14859  1.000 45.39919  ? 118 MET A HA   1 
ATOM   1838 H HB2  . MET A 1 118 ? 41.61137 15.55309 -6.49385  1.000 48.81953  ? 118 MET A HB2  1 
ATOM   1839 H HB3  . MET A 1 118 ? 40.70364 15.87736 -7.75729  1.000 48.81953  ? 118 MET A HB3  1 
ATOM   1840 H HG2  . MET A 1 118 ? 41.47670 17.95246 -7.91840  1.000 55.48654  ? 118 MET A HG2  1 
ATOM   1841 H HG3  . MET A 1 118 ? 41.99658 17.96375 -6.41673  1.000 55.48654  ? 118 MET A HG3  1 
ATOM   1842 H HE1  . MET A 1 118 ? 44.00669 15.35715 -9.34937  1.000 57.33465  ? 118 MET A HE1  1 
ATOM   1843 H HE2  . MET A 1 118 ? 42.72760 14.96078 -8.49478  1.000 57.33465  ? 118 MET A HE2  1 
ATOM   1844 H HE3  . MET A 1 118 ? 42.60485 16.03910 -9.65480  1.000 57.33465  ? 118 MET A HE3  1 
ATOM   1845 N N    . GLY A 1 119 ? 37.81835 15.99157 -7.18319  1.000 42.30393  ? 119 GLY A N    1 
ATOM   1846 C CA   . GLY A 1 119 ? 36.75956 15.14812 -7.68572  1.000 40.56434  ? 119 GLY A CA   1 
ATOM   1847 C C    . GLY A 1 119 ? 36.59337 15.36202 -9.17373  1.000 40.10387  ? 119 GLY A C    1 
ATOM   1848 O O    . GLY A 1 119 ? 37.18427 16.27035 -9.76164  1.000 43.46716  ? 119 GLY A O    1 
ATOM   1849 H H    . GLY A 1 119 ? 37.80586 16.79244 -7.49633  1.000 50.76472  ? 119 GLY A H    1 
ATOM   1850 H HA2  . GLY A 1 119 ? 36.97307 14.21609 -7.52254  1.000 48.67721  ? 119 GLY A HA2  1 
ATOM   1851 H HA3  . GLY A 1 119 ? 35.92512 15.36358 -7.24054  1.000 48.67721  ? 119 GLY A HA3  1 
ATOM   1852 N N    . MET A 1 120 ? 35.77872 14.50409 -9.78008  1.000 43.74670  ? 120 MET A N    1 
ATOM   1853 C CA   . MET A 1 120 ? 35.47863 14.59120 -11.20248 1.000 47.19367  ? 120 MET A CA   1 
ATOM   1854 C C    . MET A 1 120 ? 33.97639 14.46570 -11.39258 1.000 46.69050  ? 120 MET A C    1 
ATOM   1855 O O    . MET A 1 120 ? 33.37981 13.46140 -10.99101 1.000 46.66400  ? 120 MET A O    1 
ATOM   1856 C CB   . MET A 1 120 ? 36.21500 13.50343 -11.98909 1.000 52.12072  ? 120 MET A CB   1 
ATOM   1857 C CG   . MET A 1 120 ? 35.83079 13.43301 -13.45725 1.000 57.00530  ? 120 MET A CG   1 
ATOM   1858 S SD   . MET A 1 120 ? 36.88719 12.31986 -14.40508 1.000 83.08801  ? 120 MET A SD   1 
ATOM   1859 C CE   . MET A 1 120 ? 36.22145 10.73035 -13.92000 1.000 54.72326  ? 120 MET A CE   1 
ATOM   1860 H H    . MET A 1 120 ? 35.38247 13.85345 -9.38101  1.000 52.49604  ? 120 MET A H    1 
ATOM   1861 H HA   . MET A 1 120 ? 35.76885 15.45401 -11.53751 1.000 56.63240  ? 120 MET A HA   1 
ATOM   1862 H HB2  . MET A 1 120 ? 37.16813 13.67726 -11.94177 1.000 62.54486  ? 120 MET A HB2  1 
ATOM   1863 H HB3  . MET A 1 120 ? 36.01464 12.64221 -11.59027 1.000 62.54486  ? 120 MET A HB3  1 
ATOM   1864 H HG2  . MET A 1 120 ? 34.91775 13.11364 -13.52969 1.000 68.40636  ? 120 MET A HG2  1 
ATOM   1865 H HG3  . MET A 1 120 ? 35.90421 14.31883 -13.84564 1.000 68.40636  ? 120 MET A HG3  1 
ATOM   1866 H HE1  . MET A 1 120 ? 36.73156 10.02860 -14.35388 1.000 65.66791  ? 120 MET A HE1  1 
ATOM   1867 H HE2  . MET A 1 120 ? 36.28852 10.64061 -12.95649 1.000 65.66791  ? 120 MET A HE2  1 
ATOM   1868 H HE3  . MET A 1 120 ? 35.29197 10.68067 -14.19293 1.000 65.66791  ? 120 MET A HE3  1 
ATOM   1869 N N    . LEU A 1 121 ? 33.37062 15.48197 -11.99955 1.000 47.06507  ? 121 LEU A N    1 
ATOM   1870 C CA   . LEU A 1 121 ? 31.95014 15.42582 -12.31444 1.000 42.93586  ? 121 LEU A CA   1 
ATOM   1871 C C    . LEU A 1 121 ? 31.68831 14.34484 -13.35507 1.000 44.97380  ? 121 LEU A C    1 
ATOM   1872 O O    . LEU A 1 121 ? 32.44574 14.18778 -14.31726 1.000 48.20931  ? 121 LEU A O    1 
ATOM   1873 C CB   . LEU A 1 121 ? 31.46344 16.78177 -12.82298 1.000 45.47638  ? 121 LEU A CB   1 
ATOM   1874 C CG   . LEU A 1 121 ? 31.37380 17.89427 -11.77565 1.000 42.68295  ? 121 LEU A CG   1 
ATOM   1875 C CD1  . LEU A 1 121 ? 31.06318 19.23673 -12.42361 1.000 50.70988  ? 121 LEU A CD1  1 
ATOM   1876 C CD2  . LEU A 1 121 ? 30.32463 17.55807 -10.72477 1.000 42.39431  ? 121 LEU A CD2  1 
ATOM   1877 H H    . LEU A 1 121 ? 33.75869 16.21144 -12.23803 1.000 56.47808  ? 121 LEU A H    1 
ATOM   1878 H HA   . LEU A 1 121 ? 31.44547 15.21093 -11.51442 1.000 51.52304  ? 121 LEU A HA   1 
ATOM   1879 H HB2  . LEU A 1 121 ? 32.07510 17.08412 -13.51243 1.000 54.57165  ? 121 LEU A HB2  1 
ATOM   1880 H HB3  . LEU A 1 121 ? 30.57544 16.66476 -13.19534 1.000 54.57165  ? 121 LEU A HB3  1 
ATOM   1881 H HG   . LEU A 1 121 ? 32.23473 17.97008 -11.33526 1.000 51.21954  ? 121 LEU A HG   1 
ATOM   1882 H HD11 . LEU A 1 121 ? 31.76241 19.44878 -13.06159 1.000 60.85186  ? 121 LEU A HD11 1 
ATOM   1883 H HD12 . LEU A 1 121 ? 30.20797 19.17795 -12.87755 1.000 60.85186  ? 121 LEU A HD12 1 
ATOM   1884 H HD13 . LEU A 1 121 ? 31.02590 19.91873 -11.73486 1.000 60.85186  ? 121 LEU A HD13 1 
ATOM   1885 H HD21 . LEU A 1 121 ? 30.66201 16.84690 -10.15792 1.000 50.87317  ? 121 LEU A HD21 1 
ATOM   1886 H HD22 . LEU A 1 121 ? 30.14622 18.34899 -10.19232 1.000 50.87317  ? 121 LEU A HD22 1 
ATOM   1887 H HD23 . LEU A 1 121 ? 29.51283 17.26910 -11.17015 1.000 50.87317  ? 121 LEU A HD23 1 
ATOM   1888 N N    . LEU A 1 122 ? 30.61112 13.59333 -13.15191 1.000 52.38653  ? 122 LEU A N    1 
ATOM   1889 C CA   . LEU A 1 122 ? 30.25778 12.49289 -14.04162 1.000 51.54768  ? 122 LEU A CA   1 
ATOM   1890 C C    . LEU A 1 122 ? 29.02007 12.85593 -14.85484 1.000 48.35185  ? 122 LEU A C    1 
ATOM   1891 O O    . LEU A 1 122 ? 28.99171 12.67829 -16.07148 1.000 62.31921  ? 122 LEU A O    1 
ATOM   1892 C CB   . LEU A 1 122 ? 30.01049 11.21384 -13.24160 1.000 47.51420  ? 122 LEU A CB   1 
ATOM   1893 C CG   . LEU A 1 122 ? 31.12824 10.80546 -12.27962 1.000 51.79789  ? 122 LEU A CG   1 
ATOM   1894 C CD1  . LEU A 1 122 ? 30.62515 9.77238  -11.27979 1.000 55.14821  ? 122 LEU A CD1  1 
ATOM   1895 C CD2  . LEU A 1 122 ? 32.33848 10.26964 -13.03247 1.000 52.59843  ? 122 LEU A CD2  1 
ATOM   1896 H H    . LEU A 1 122 ? 30.06255 13.70168 -12.49851 1.000 62.86383  ? 122 LEU A H    1 
ATOM   1897 H HA   . LEU A 1 122 ? 30.99031 12.31849 -14.65308 1.000 61.85721  ? 122 LEU A HA   1 
ATOM   1898 H HB2  . LEU A 1 122 ? 29.20620 11.33693 -12.71352 1.000 57.01704  ? 122 LEU A HB2  1 
ATOM   1899 H HB3  . LEU A 1 122 ? 29.88767 10.48324 -13.86774 1.000 57.01704  ? 122 LEU A HB3  1 
ATOM   1900 H HG   . LEU A 1 122 ? 31.41141 11.59324 -11.78962 1.000 62.15746  ? 122 LEU A HG   1 
ATOM   1901 H HD11 . LEU A 1 122 ? 31.35451 9.52043  -10.69204 1.000 66.17785  ? 122 LEU A HD11 1 
ATOM   1902 H HD12 . LEU A 1 122 ? 29.90201 10.15982 -10.76224 1.000 66.17785  ? 122 LEU A HD12 1 
ATOM   1903 H HD13 . LEU A 1 122 ? 30.30601 8.99433  -11.76320 1.000 66.17785  ? 122 LEU A HD13 1 
ATOM   1904 H HD21 . LEU A 1 122 ? 33.01843 10.00813 -12.39202 1.000 63.11812  ? 122 LEU A HD21 1 
ATOM   1905 H HD22 . LEU A 1 122 ? 32.06786 9.50173  -13.55970 1.000 63.11812  ? 122 LEU A HD22 1 
ATOM   1906 H HD23 . LEU A 1 122 ? 32.68215 10.96569 -13.61411 1.000 63.11812  ? 122 LEU A HD23 1 
ATOM   1907 N N    . LEU A 1 132 ? 25.87722 22.25320 -17.40644 1.000 78.52667  ? 132 LEU A N    1 
ATOM   1908 C CA   . LEU A 1 132 ? 25.58847 21.01422 -16.69078 1.000 79.06269  ? 132 LEU A CA   1 
ATOM   1909 C C    . LEU A 1 132 ? 26.65511 20.76535 -15.62008 1.000 81.84200  ? 132 LEU A C    1 
ATOM   1910 O O    . LEU A 1 132 ? 26.80249 19.64347 -15.13319 1.000 83.95638  ? 132 LEU A O    1 
ATOM   1911 C CB   . LEU A 1 132 ? 25.51495 19.84029 -17.67180 1.000 93.07938  ? 132 LEU A CB   1 
ATOM   1912 C CG   . LEU A 1 132 ? 24.66035 18.63014 -17.28379 1.000 97.80500  ? 132 LEU A CG   1 
ATOM   1913 C CD1  . LEU A 1 132 ? 23.18353 18.99047 -17.18504 1.000 93.85437  ? 132 LEU A CD1  1 
ATOM   1914 C CD2  . LEU A 1 132 ? 24.85884 17.49258 -18.28268 1.000 86.57617  ? 132 LEU A CD2  1 
ATOM   1915 H HA   . LEU A 1 132 ? 24.72710 21.07712 -16.24921 1.000 94.87523  ? 132 LEU A HA   1 
ATOM   1916 H HB2  . LEU A 1 132 ? 25.15679 20.17738 -18.50785 1.000 111.69526 ? 132 LEU A HB2  1 
ATOM   1917 H HB3  . LEU A 1 132 ? 26.41775 19.51192 -17.80604 1.000 111.69526 ? 132 LEU A HB3  1 
ATOM   1918 H HG   . LEU A 1 132 ? 24.94635 18.32962 -16.40699 1.000 117.36600 ? 132 LEU A HG   1 
ATOM   1919 H HD11 . LEU A 1 132 ? 22.91285 19.43978 -18.00098 1.000 112.62524 ? 132 LEU A HD11 1 
ATOM   1920 H HD12 . LEU A 1 132 ? 22.66727 18.17763 -17.06815 1.000 112.62524 ? 132 LEU A HD12 1 
ATOM   1921 H HD13 . LEU A 1 132 ? 23.05200 19.57810 -16.42459 1.000 112.62524 ? 132 LEU A HD13 1 
ATOM   1922 H HD21 . LEU A 1 132 ? 25.79471 17.23762 -18.28907 1.000 103.89140 ? 132 LEU A HD21 1 
ATOM   1923 H HD22 . LEU A 1 132 ? 24.31215 16.73761 -18.01424 1.000 103.89140 ? 132 LEU A HD22 1 
ATOM   1924 H HD23 . LEU A 1 132 ? 24.59281 17.79665 -19.16454 1.000 103.89140 ? 132 LEU A HD23 1 
ATOM   1925 N N    . GLY A 1 133 ? 27.38649 21.82209 -15.25459 1.000 71.39425  ? 133 GLY A N    1 
ATOM   1926 C CA   . GLY A 1 133 ? 28.45548 21.72725 -14.27316 1.000 57.94719  ? 133 GLY A CA   1 
ATOM   1927 C C    . GLY A 1 133 ? 28.32456 22.72432 -13.13622 1.000 55.57088  ? 133 GLY A C    1 
ATOM   1928 O O    . GLY A 1 133 ? 27.22027 23.19583 -12.85599 1.000 60.01489  ? 133 GLY A O    1 
ATOM   1929 H H    . GLY A 1 133 ? 27.27738 22.61528 -15.56851 1.000 85.67310  ? 133 GLY A H    1 
ATOM   1930 H HA2  . GLY A 1 133 ? 28.45716 20.83511 -13.89239 1.000 69.53662  ? 133 GLY A HA2  1 
ATOM   1931 H HA3  . GLY A 1 133 ? 29.30496 21.88385 -14.71448 1.000 69.53662  ? 133 GLY A HA3  1 
ATOM   1932 N N    . THR A 1 134 ? 29.43278 23.05558 -12.46991 1.000 47.01220  ? 134 THR A N    1 
ATOM   1933 C CA   . THR A 1 134 ? 29.40446 23.98684 -11.34937 1.000 48.60370  ? 134 THR A CA   1 
ATOM   1934 C C    . THR A 1 134 ? 29.68860 25.40918 -11.82074 1.000 47.23555  ? 134 THR A C    1 
ATOM   1935 O O    . THR A 1 134 ? 30.35156 25.63032 -12.83625 1.000 43.48320  ? 134 THR A O    1 
ATOM   1936 C CB   . THR A 1 134 ? 30.41939 23.59852 -10.27057 1.000 42.77930  ? 134 THR A CB   1 
ATOM   1937 O OG1  . THR A 1 134 ? 31.73539 23.53910 -10.83667 1.000 43.36876  ? 134 THR A OG1  1 
ATOM   1938 C CG2  . THR A 1 134 ? 30.07126 22.25218 -9.66081  1.000 44.23960  ? 134 THR A CG2  1 
ATOM   1939 H H    . THR A 1 134 ? 30.21606 22.75056 -12.65164 1.000 56.41464  ? 134 THR A H    1 
ATOM   1940 H HA   . THR A 1 134 ? 28.51971 23.96116 -10.95258 1.000 58.32444  ? 134 THR A HA   1 
ATOM   1941 H HB   . THR A 1 134 ? 30.40318 24.26460 -9.56560  1.000 51.33516  ? 134 THR A HB   1 
ATOM   1942 H HG1  . THR A 1 134 ? 32.27925 23.24320 -10.26899 1.000 52.04251  ? 134 THR A HG1  1 
ATOM   1943 H HG21 . THR A 1 134 ? 29.21853 22.30645 -9.20167  1.000 53.08752  ? 134 THR A HG21 1 
ATOM   1944 H HG22 . THR A 1 134 ? 30.01210 21.57841 -10.35611 1.000 53.08752  ? 134 THR A HG22 1 
ATOM   1945 H HG23 . THR A 1 134 ? 30.75497 21.98920 -9.02498  1.000 53.08752  ? 134 THR A HG23 1 
ATOM   1946 N N    . THR A 1 135 ? 29.18872 26.37473 -11.04243 1.000 49.47727  ? 135 THR A N    1 
ATOM   1947 C CA   . THR A 1 135 ? 29.20309 27.78360 -11.41847 1.000 45.60345  ? 135 THR A CA   1 
ATOM   1948 C C    . THR A 1 135 ? 29.65688 28.65108 -10.25219 1.000 41.61329  ? 135 THR A C    1 
ATOM   1949 O O    . THR A 1 135 ? 29.76872 28.16162 -9.11113  1.000 39.93181  ? 135 THR A O    1 
ATOM   1950 C CB   . THR A 1 135 ? 27.81660 28.22536 -11.88487 1.000 47.25384  ? 135 THR A CB   1 
ATOM   1951 O OG1  . THR A 1 135 ? 26.90835 28.21458 -10.77282 1.000 47.73862  ? 135 THR A OG1  1 
ATOM   1952 C CG2  . THR A 1 135 ? 27.28818 27.29264 -12.96796 1.000 55.24138  ? 135 THR A CG2  1 
ATOM   1953 H H    . THR A 1 135 ? 28.82833 26.23187 -10.27476 1.000 59.37272  ? 135 THR A H    1 
ATOM   1954 H HA   . THR A 1 135 ? 29.83435 27.90367 -12.14510 1.000 54.72414  ? 135 THR A HA   1 
ATOM   1955 H HB   . THR A 1 135 ? 27.87370 29.12115 -12.25258 1.000 56.70460  ? 135 THR A HB   1 
ATOM   1956 H HG1  . THR A 1 135 ? 26.16118 28.51703 -11.00918 1.000 57.28634  ? 135 THR A HG1  1 
ATOM   1957 H HG21 . THR A 1 135 ? 26.42351 27.60253 -13.27975 1.000 66.28965  ? 135 THR A HG21 1 
ATOM   1958 H HG22 . THR A 1 135 ? 27.90397 27.27170 -13.71714 1.000 66.28965  ? 135 THR A HG22 1 
ATOM   1959 H HG23 . THR A 1 135 ? 27.19195 26.39452 -12.61437 1.000 66.28965  ? 135 THR A HG23 1 
ATOM   1960 N N    . PRO A 1 136 ? 29.90688 29.93654 -10.48319 1.000 47.17074  ? 136 PRO A N    1 
ATOM   1961 C CA   . PRO A 1 136 ? 30.43134 30.80691 -9.42142  1.000 51.90569  ? 136 PRO A CA   1 
ATOM   1962 C C    . PRO A 1 136 ? 29.60630 30.84494 -8.14622  1.000 52.91864  ? 136 PRO A C    1 
ATOM   1963 O O    . PRO A 1 136 ? 30.18508 30.97516 -7.06191  1.000 56.41797  ? 136 PRO A O    1 
ATOM   1964 C CB   . PRO A 1 136 ? 30.47009 32.18139 -10.10649 1.000 45.46988  ? 136 PRO A CB   1 
ATOM   1965 C CG   . PRO A 1 136 ? 30.72364 31.85329 -11.54115 1.000 50.50804  ? 136 PRO A CG   1 
ATOM   1966 C CD   . PRO A 1 136 ? 29.93588 30.59563 -11.80677 1.000 48.14552  ? 136 PRO A CD   1 
ATOM   1967 H HA   . PRO A 1 136 ? 31.32819 30.51770 -9.19136  1.000 62.28683  ? 136 PRO A HA   1 
ATOM   1968 H HB2  . PRO A 1 136 ? 29.62078 32.63634 -9.99422  1.000 54.56386  ? 136 PRO A HB2  1 
ATOM   1969 H HB3  . PRO A 1 136 ? 31.18667 32.72054 -9.73673  1.000 54.56386  ? 136 PRO A HB3  1 
ATOM   1970 H HG2  . PRO A 1 136 ? 30.41499 32.57991 -12.10477 1.000 60.60964  ? 136 PRO A HG2  1 
ATOM   1971 H HG3  . PRO A 1 136 ? 31.67157 31.70360 -11.68228 1.000 60.60964  ? 136 PRO A HG3  1 
ATOM   1972 H HD2  . PRO A 1 136 ? 29.03844 30.80619 -12.10872 1.000 57.77462  ? 136 PRO A HD2  1 
ATOM   1973 H HD3  . PRO A 1 136 ? 30.38400 30.03794 -12.46180 1.000 57.77462  ? 136 PRO A HD3  1 
ATOM   1974 N N    . GLY A 1 137 ? 28.28478 30.74186 -8.23067  1.000 44.13916  ? 137 GLY A N    1 
ATOM   1975 C CA   . GLY A 1 137 ? 27.46254 30.84426 -7.04586  1.000 39.38605  ? 137 GLY A CA   1 
ATOM   1976 C C    . GLY A 1 137 ? 27.31281 29.58381 -6.23019  1.000 38.77043  ? 137 GLY A C    1 
ATOM   1977 O O    . GLY A 1 137 ? 26.56162 29.58119 -5.25256  1.000 37.76397  ? 137 GLY A O    1 
ATOM   1978 H H    . GLY A 1 137 ? 27.84969 30.61332 -8.96126  1.000 52.96699  ? 137 GLY A H    1 
ATOM   1979 H HA2  . GLY A 1 137 ? 27.84496 31.52159 -6.46630  1.000 47.26326  ? 137 GLY A HA2  1 
ATOM   1980 H HA3  . GLY A 1 137 ? 26.57336 31.12382 -7.31440  1.000 47.26326  ? 137 GLY A HA3  1 
ATOM   1981 N N    . ASP A 1 138 ? 28.02232 28.51215 -6.57987  1.000 32.94965  ? 138 ASP A N    1 
ATOM   1982 C CA   . ASP A 1 138 ? 27.79420 27.20924 -5.97179  1.000 38.71963  ? 138 ASP A CA   1 
ATOM   1983 C C    . ASP A 1 138 ? 28.66938 26.91987 -4.75943  1.000 38.75271  ? 138 ASP A C    1 
ATOM   1984 O O    . ASP A 1 138 ? 28.50462 25.86297 -4.14244  1.000 34.32938  ? 138 ASP A O    1 
ATOM   1985 C CB   . ASP A 1 138 ? 28.02482 26.09231 -6.99716  1.000 38.06000  ? 138 ASP A CB   1 
ATOM   1986 C CG   . ASP A 1 138 ? 27.08525 26.17518 -8.17429  1.000 42.89235  ? 138 ASP A CG   1 
ATOM   1987 O OD1  . ASP A 1 138 ? 26.04643 26.86015 -8.06709  1.000 40.21368  ? 138 ASP A OD1  1 
ATOM   1988 O OD2  . ASP A 1 138 ? 27.38347 25.54507 -9.21072  1.000 41.51505  ? 138 ASP A OD2  1 
ATOM   1989 H H    . ASP A 1 138 ? 28.64585 28.51758 -7.17214  1.000 39.53958  ? 138 ASP A H    1 
ATOM   1990 H HA   . ASP A 1 138 ? 26.86828 27.19439 -5.68307  1.000 46.46356  ? 138 ASP A HA   1 
ATOM   1991 H HB2  . ASP A 1 138 ? 28.93254 26.15476 -7.33338  1.000 45.67200  ? 138 ASP A HB2  1 
ATOM   1992 H HB3  . ASP A 1 138 ? 27.88924 25.23434 -6.56542  1.000 45.67200  ? 138 ASP A HB3  1 
ATOM   1993 N N    . CYS A 1 139 ? 29.60041 27.79369 -4.40126  1.000 30.66366  ? 139 CYS A N    1 
ATOM   1994 C CA   . CYS A 1 139 ? 30.51966 27.43627 -3.33171  1.000 31.10475  ? 139 CYS A CA   1 
ATOM   1995 C C    . CYS A 1 139 ? 29.79762 27.38982 -1.99472  1.000 35.28737  ? 139 CYS A C    1 
ATOM   1996 O O    . CYS A 1 139 ? 28.91300 28.20479 -1.70871  1.000 29.97456  ? 139 CYS A O    1 
ATOM   1997 C CB   . CYS A 1 139 ? 31.69957 28.39702 -3.27941  1.000 37.50134  ? 139 CYS A CB   1 
ATOM   1998 S SG   . CYS A 1 139 ? 33.03679 27.72059 -4.27400  1.000 44.22832  ? 139 CYS A SG   1 
ATOM   1999 H H    . CYS A 1 139 ? 29.71674 28.57165 -4.74889  1.000 36.79639  ? 139 CYS A H    1 
ATOM   2000 H HA   . CYS A 1 139 ? 30.87912 26.55234 -3.50594  1.000 37.32570  ? 139 CYS A HA   1 
ATOM   2001 H HB2  . CYS A 1 139 ? 31.44063 29.25954 -3.63984  1.000 45.00161  ? 139 CYS A HB2  1 
ATOM   2002 H HB3  . CYS A 1 139 ? 32.00425 28.49790 -2.36405  1.000 45.00161  ? 139 CYS A HB3  1 
ATOM   2003 H HG   . CYS A 1 139 ? 33.04425 26.52621 -4.15817  1.000 53.07398  ? 139 CYS A HG   1 
ATOM   2004 N N    . GLY A 1 140 ? 30.17445 26.40441 -1.18320  1.000 34.80863  ? 140 GLY A N    1 
ATOM   2005 C CA   . GLY A 1 140 ? 29.51548 26.12239 0.06945   1.000 37.76264  ? 140 GLY A CA   1 
ATOM   2006 C C    . GLY A 1 140 ? 28.52399 24.98051 0.01483   1.000 35.50949  ? 140 GLY A C    1 
ATOM   2007 O O    . GLY A 1 140 ? 28.11354 24.49066 1.07366   1.000 30.04885  ? 140 GLY A O    1 
ATOM   2008 H H    . GLY A 1 140 ? 30.83057 25.87386 -1.34940  1.000 41.77036  ? 140 GLY A H    1 
ATOM   2009 H HA2  . GLY A 1 140 ? 30.18778 25.90068 0.73259   1.000 45.31517  ? 140 GLY A HA2  1 
ATOM   2010 H HA3  . GLY A 1 140 ? 29.03844 26.91664 0.35669   1.000 45.31517  ? 140 GLY A HA3  1 
ATOM   2011 N N    . CYS A 1 141 ? 28.12443 24.54502 -1.17693  1.000 31.02054  ? 141 CYS A N    1 
ATOM   2012 C CA   . CYS A 1 141 ? 27.21348 23.41709 -1.28227  1.000 36.41402  ? 141 CYS A CA   1 
ATOM   2013 C C    . CYS A 1 141 ? 27.93864 22.13063 -0.88861  1.000 35.73469  ? 141 CYS A C    1 
ATOM   2014 O O    . CYS A 1 141 ? 29.14649 21.99682 -1.10192  1.000 34.89473  ? 141 CYS A O    1 
ATOM   2015 C CB   . CYS A 1 141 ? 26.65882 23.30596 -2.69823  1.000 35.77188  ? 141 CYS A CB   1 
ATOM   2016 S SG   . CYS A 1 141 ? 25.55360 24.66325 -3.15888  1.000 35.67931  ? 141 CYS A SG   1 
ATOM   2017 H H    . CYS A 1 141 ? 28.36489 24.88315 -1.93022  1.000 37.22465  ? 141 CYS A H    1 
ATOM   2018 H HA   . CYS A 1 141 ? 26.46026 23.53886 -0.68332  1.000 43.69682  ? 141 CYS A HA   1 
ATOM   2019 H HB2  . CYS A 1 141 ? 27.40016 23.30264 -3.32378  1.000 42.92626  ? 141 CYS A HB2  1 
ATOM   2020 H HB3  . CYS A 1 141 ? 26.15826 22.47843 -2.77262  1.000 42.92626  ? 141 CYS A HB3  1 
ATOM   2021 H HG   . CYS A 1 141 ? 25.17639 24.49471 -4.28552  1.000 42.81518  ? 141 CYS A HG   1 
ATOM   2022 N N    . PRO A 1 142 ? 27.22838 21.17399 -0.29864  1.000 36.36050  ? 142 PRO A N    1 
ATOM   2023 C CA   . PRO A 1 142 ? 27.89339 19.99246 0.25776   1.000 37.61250  ? 142 PRO A CA   1 
ATOM   2024 C C    . PRO A 1 142 ? 28.09120 18.85482 -0.73182  1.000 37.88801  ? 142 PRO A C    1 
ATOM   2025 O O    . PRO A 1 142 ? 27.31628 18.65228 -1.66746  1.000 40.03009  ? 142 PRO A O    1 
ATOM   2026 C CB   . PRO A 1 142 ? 26.92235 19.56488 1.36997   1.000 39.94913  ? 142 PRO A CB   1 
ATOM   2027 C CG   . PRO A 1 142 ? 25.58341 19.89712 0.77770   1.000 35.37891  ? 142 PRO A CG   1 
ATOM   2028 C CD   . PRO A 1 142 ? 25.80115 21.22261 0.07814   1.000 36.33015  ? 142 PRO A CD   1 
ATOM   2029 H HA   . PRO A 1 142 ? 28.75854 20.24065 0.61945   1.000 45.13500  ? 142 PRO A HA   1 
ATOM   2030 H HB2  . PRO A 1 142 ? 27.00692 18.61529 1.54893   1.000 47.93896  ? 142 PRO A HB2  1 
ATOM   2031 H HB3  . PRO A 1 142 ? 27.08894 20.07133 2.18031   1.000 47.93896  ? 142 PRO A HB3  1 
ATOM   2032 H HG2  . PRO A 1 142 ? 25.31781 19.20927 0.14745   1.000 42.45469  ? 142 PRO A HG2  1 
ATOM   2033 H HG3  . PRO A 1 142 ? 24.91916 19.97801 1.47993   1.000 42.45469  ? 142 PRO A HG3  1 
ATOM   2034 H HD2  . PRO A 1 142 ? 25.23823 21.29488 -0.70850  1.000 43.59618  ? 142 PRO A HD2  1 
ATOM   2035 H HD3  . PRO A 1 142 ? 25.62745 21.96354 0.67959   1.000 43.59618  ? 142 PRO A HD3  1 
ATOM   2036 N N    . TYR A 1 143 ? 29.16997 18.10706 -0.50317  1.000 36.34421  ? 143 TYR A N    1 
ATOM   2037 C CA   . TYR A 1 143 ? 29.39914 16.81422 -1.13715  1.000 36.59410  ? 143 TYR A CA   1 
ATOM   2038 C C    . TYR A 1 143 ? 28.89811 15.74336 -0.17267  1.000 38.91136  ? 143 TYR A C    1 
ATOM   2039 O O    . TYR A 1 143 ? 29.34209 15.69188 0.97961   1.000 37.43917  ? 143 TYR A O    1 
ATOM   2040 C CB   . TYR A 1 143 ? 30.87885 16.59652 -1.45124  1.000 38.17907  ? 143 TYR A CB   1 
ATOM   2041 C CG   . TYR A 1 143 ? 31.43429 17.44849 -2.57236  1.000 40.44687  ? 143 TYR A CG   1 
ATOM   2042 C CD1  . TYR A 1 143 ? 31.64625 18.80901 -2.39992  1.000 38.44417  ? 143 TYR A CD1  1 
ATOM   2043 C CD2  . TYR A 1 143 ? 31.77325 16.88368 -3.79503  1.000 44.19851  ? 143 TYR A CD2  1 
ATOM   2044 C CE1  . TYR A 1 143 ? 32.16556 19.58620 -3.41830  1.000 39.61988  ? 143 TYR A CE1  1 
ATOM   2045 C CE2  . TYR A 1 143 ? 32.29094 17.65156 -4.81771  1.000 46.07535  ? 143 TYR A CE2  1 
ATOM   2046 C CZ   . TYR A 1 143 ? 32.48492 19.00177 -4.62430  1.000 43.65307  ? 143 TYR A CZ   1 
ATOM   2047 O OH   . TYR A 1 143 ? 33.00141 19.76870 -5.64396  1.000 42.00987  ? 143 TYR A OH   1 
ATOM   2048 H H    . TYR A 1 143 ? 29.80214 18.33667 0.03279   1.000 43.61305  ? 143 TYR A H    1 
ATOM   2049 H HA   . TYR A 1 143 ? 28.91343 16.76289 -1.97521  1.000 43.91292  ? 143 TYR A HA   1 
ATOM   2050 H HB2  . TYR A 1 143 ? 31.39344 16.79631 -0.65363  1.000 45.81489  ? 143 TYR A HB2  1 
ATOM   2051 H HB3  . TYR A 1 143 ? 31.00467 15.66836 -1.70339  1.000 45.81489  ? 143 TYR A HB3  1 
ATOM   2052 H HD1  . TYR A 1 143 ? 31.43529 19.20474 -1.58518  1.000 46.13300  ? 143 TYR A HD1  1 
ATOM   2053 H HD2  . TYR A 1 143 ? 31.64904 15.97148 -3.92678  1.000 53.03821  ? 143 TYR A HD2  1 
ATOM   2054 H HE1  . TYR A 1 143 ? 32.29849 20.49769 -3.29017  1.000 47.54385  ? 143 TYR A HE1  1 
ATOM   2055 H HE2  . TYR A 1 143 ? 32.50770 17.25999 -5.63293  1.000 55.29041  ? 143 TYR A HE2  1 
ATOM   2056 H HH   . TYR A 1 143 ? 33.19654 19.28122 -6.29961  1.000 50.41185  ? 143 TYR A HH   1 
ATOM   2057 N N    . ILE A 1 144 ? 27.98204 14.89667 -0.63667  1.000 39.59364  ? 144 ILE A N    1 
ATOM   2058 C CA   . ILE A 1 144 ? 27.26557 13.95605 0.21755   1.000 38.73421  ? 144 ILE A CA   1 
ATOM   2059 C C    . ILE A 1 144 ? 27.30996 12.57308 -0.41709  1.000 40.63269  ? 144 ILE A C    1 
ATOM   2060 O O    . ILE A 1 144 ? 27.25673 12.44371 -1.64480  1.000 39.10967  ? 144 ILE A O    1 
ATOM   2061 C CB   . ILE A 1 144 ? 25.79820 14.40201 0.42991   1.000 42.30918  ? 144 ILE A CB   1 
ATOM   2062 C CG1  . ILE A 1 144 ? 25.73270 15.72493 1.20206   1.000 44.53996  ? 144 ILE A CG1  1 
ATOM   2063 C CG2  . ILE A 1 144 ? 24.99208 13.30468 1.12330   1.000 53.59927  ? 144 ILE A CG2  1 
ATOM   2064 C CD1  . ILE A 1 144 ? 25.67099 15.57461 2.70257   1.000 50.16050  ? 144 ILE A CD1  1 
ATOM   2065 H H    . ILE A 1 144 ? 27.75338 14.84814 -1.46429  1.000 47.51236  ? 144 ILE A H    1 
ATOM   2066 H HA   . ILE A 1 144 ? 27.70944 13.90624 1.07860   1.000 46.48106  ? 144 ILE A HA   1 
ATOM   2067 H HB   . ILE A 1 144 ? 25.40067 14.55432 -0.44168  1.000 50.77102  ? 144 ILE A HB   1 
ATOM   2068 H HG12 . ILE A 1 144 ? 26.52487 16.24403 0.99254   1.000 53.44795  ? 144 ILE A HG12 1 
ATOM   2069 H HG13 . ILE A 1 144 ? 24.93768 16.20578 0.92344   1.000 53.44795  ? 144 ILE A HG13 1 
ATOM   2070 H HG21 . ILE A 1 144 ? 24.10885 13.64637 1.33315   1.000 64.31912  ? 144 ILE A HG21 1 
ATOM   2071 H HG22 . ILE A 1 144 ? 24.91899 12.54241 0.52790   1.000 64.31912  ? 144 ILE A HG22 1 
ATOM   2072 H HG23 . ILE A 1 144 ? 25.44860 13.04486 1.93877   1.000 64.31912  ? 144 ILE A HG23 1 
ATOM   2073 H HD11 . ILE A 1 144 ? 25.71400 16.45382 3.11006   1.000 60.19259  ? 144 ILE A HD11 1 
ATOM   2074 H HD12 . ILE A 1 144 ? 24.83799 15.13929 2.94235   1.000 60.19259  ? 144 ILE A HD12 1 
ATOM   2075 H HD13 . ILE A 1 144 ? 26.42226 15.03637 2.99719   1.000 60.19259  ? 144 ILE A HD13 1 
ATOM   2076 N N    . TYR A 1 145 ? 27.39582 11.53780 0.41798   1.000 44.35015  ? 145 TYR A N    1 
ATOM   2077 C CA   . TYR A 1 145 ? 27.23727 10.16635 -0.05078  1.000 47.12981  ? 145 TYR A CA   1 
ATOM   2078 C C    . TYR A 1 145 ? 26.67719 9.32905  1.08959   1.000 47.79066  ? 145 TYR A C    1 
ATOM   2079 O O    . TYR A 1 145 ? 26.76339 9.70625  2.26070   1.000 48.53932  ? 145 TYR A O    1 
ATOM   2080 C CB   . TYR A 1 145 ? 28.55898 9.58845  -0.59332  1.000 42.14680  ? 145 TYR A CB   1 
ATOM   2081 C CG   . TYR A 1 145 ? 29.55938 9.06674  0.42490   1.000 41.69957  ? 145 TYR A CG   1 
ATOM   2082 C CD1  . TYR A 1 145 ? 30.44098 9.92356  1.07498   1.000 40.48626  ? 145 TYR A CD1  1 
ATOM   2083 C CD2  . TYR A 1 145 ? 29.65501 7.70633  0.69719   1.000 49.11311  ? 145 TYR A CD2  1 
ATOM   2084 C CE1  . TYR A 1 145 ? 31.37119 9.44239  1.99118   1.000 38.26921  ? 145 TYR A CE1  1 
ATOM   2085 C CE2  . TYR A 1 145 ? 30.58088 7.21693  1.60962   1.000 49.78780  ? 145 TYR A CE2  1 
ATOM   2086 C CZ   . TYR A 1 145 ? 31.43549 8.08945  2.25202   1.000 40.23012  ? 145 TYR A CZ   1 
ATOM   2087 O OH   . TYR A 1 145 ? 32.35314 7.60527  3.15703   1.000 56.60860  ? 145 TYR A OH   1 
ATOM   2088 H H    . TYR A 1 145 ? 27.54560 11.60585 1.26210   1.000 53.22018  ? 145 TYR A H    1 
ATOM   2089 H HA   . TYR A 1 145 ? 26.59759 10.13725 -0.77939  1.000 56.55577  ? 145 TYR A HA   1 
ATOM   2090 H HB2  . TYR A 1 145 ? 28.34192 8.84685  -1.17968  1.000 50.57616  ? 145 TYR A HB2  1 
ATOM   2091 H HB3  . TYR A 1 145 ? 29.00681 10.28772 -1.09468  1.000 50.57616  ? 145 TYR A HB3  1 
ATOM   2092 H HD1  . TYR A 1 145 ? 30.40823 10.83519 0.89398   1.000 48.58351  ? 145 TYR A HD1  1 
ATOM   2093 H HD2  . TYR A 1 145 ? 29.08809 7.11279  0.25990   1.000 58.93573  ? 145 TYR A HD2  1 
ATOM   2094 H HE1  . TYR A 1 145 ? 31.94659 10.02998 2.42543   1.000 45.92306  ? 145 TYR A HE1  1 
ATOM   2095 H HE2  . TYR A 1 145 ? 30.62467 6.30502  1.78688   1.000 59.74536  ? 145 TYR A HE2  1 
ATOM   2096 H HH   . TYR A 1 145 ? 32.31274 6.76676  3.18646   1.000 67.93032  ? 145 TYR A HH   1 
ATOM   2097 N N    . LYS A 1 146 ? 26.07537 8.19620  0.73392   1.000 49.97382  ? 146 LYS A N    1 
ATOM   2098 C CA   . LYS A 1 146 ? 25.45639 7.31237  1.71183   1.000 57.04831  ? 146 LYS A CA   1 
ATOM   2099 C C    . LYS A 1 146 ? 26.35324 6.11039  1.97172   1.000 52.25889  ? 146 LYS A C    1 
ATOM   2100 O O    . LYS A 1 146 ? 26.89160 5.50834  1.03760   1.000 48.63134  ? 146 LYS A O    1 
ATOM   2101 C CB   . LYS A 1 146 ? 24.08201 6.82451  1.24705   1.000 53.85172  ? 146 LYS A CB   1 
ATOM   2102 C CG   . LYS A 1 146 ? 23.09941 6.56667  2.39578   1.000 61.13763  ? 146 LYS A CG   1 
ATOM   2103 C CD   . LYS A 1 146 ? 22.04644 5.52732  2.01847   1.000 68.46792  ? 146 LYS A CD   1 
ATOM   2104 C CE   . LYS A 1 146 ? 20.67744 5.85460  2.60214   1.000 74.16066  ? 146 LYS A CE   1 
ATOM   2105 N NZ   . LYS A 1 146 ? 19.58510 5.48677  1.65458   1.000 76.88303  ? 146 LYS A NZ   1 
ATOM   2106 H H    . LYS A 1 146 ? 26.01334 7.91726  -0.07722  1.000 59.96858  ? 146 LYS A H    1 
ATOM   2107 H HA   . LYS A 1 146 ? 25.33749 7.80403  2.53950   1.000 68.45798  ? 146 LYS A HA   1 
ATOM   2108 H HB2  . LYS A 1 146 ? 23.69127 7.49757  0.66806   1.000 64.62207  ? 146 LYS A HB2  1 
ATOM   2109 H HB3  . LYS A 1 146 ? 24.19413 5.99290  0.76047   1.000 64.62207  ? 146 LYS A HB3  1 
ATOM   2110 H HG2  . LYS A 1 146 ? 23.58751 6.23824  3.16701   1.000 73.36516  ? 146 LYS A HG2  1 
ATOM   2111 H HG3  . LYS A 1 146 ? 22.64370 7.39336  2.61898   1.000 73.36516  ? 146 LYS A HG3  1 
ATOM   2112 H HD2  . LYS A 1 146 ? 21.96270 5.49499  1.05263   1.000 82.16150  ? 146 LYS A HD2  1 
ATOM   2113 H HD3  . LYS A 1 146 ? 22.31927 4.66023  2.35702   1.000 82.16150  ? 146 LYS A HD3  1 
ATOM   2114 H HE2  . LYS A 1 146 ? 20.55022 5.35630  3.42459   1.000 88.99279  ? 146 LYS A HE2  1 
ATOM   2115 H HE3  . LYS A 1 146 ? 20.62176 6.80669  2.77910   1.000 88.99279  ? 146 LYS A HE3  1 
ATOM   2116 H HZ1  . LYS A 1 146 ? 18.79373 5.68327  2.01126   1.000 92.25964  ? 146 LYS A HZ1  1 
ATOM   2117 H HZ2  . LYS A 1 146 ? 19.67845 5.93733  0.89275   1.000 92.25964  ? 146 LYS A HZ2  1 
ATOM   2118 H HZ3  . LYS A 1 146 ? 19.61460 4.61460  1.47981   1.000 92.25964  ? 146 LYS A HZ3  1 
ATOM   2119 N N    . ARG A 1 147 ? 26.50130 5.76122  3.24317   1.000 61.41300  ? 147 ARG A N    1 
ATOM   2120 C CA   . ARG A 1 147 ? 27.28110 4.60256  3.67051   1.000 58.33053  ? 147 ARG A CA   1 
ATOM   2121 C C    . ARG A 1 147 ? 26.34944 3.72159  4.49333   1.000 62.25983  ? 147 ARG A C    1 
ATOM   2122 O O    . ARG A 1 147 ? 26.11628 3.98760  5.67678   1.000 62.09466  ? 147 ARG A O    1 
ATOM   2123 C CB   . ARG A 1 147 ? 28.50740 5.03183  4.46556   1.000 56.74105  ? 147 ARG A CB   1 
ATOM   2124 C CG   . ARG A 1 147 ? 29.44865 3.89578  4.82990   1.000 63.56759  ? 147 ARG A CG   1 
ATOM   2125 C CD   . ARG A 1 147 ? 30.72699 4.45014  5.43667   1.000 59.27055  ? 147 ARG A CD   1 
ATOM   2126 N NE   . ARG A 1 147 ? 30.44555 5.26785  6.61038   1.000 55.57038  ? 147 ARG A NE   1 
ATOM   2127 C CZ   . ARG A 1 147 ? 31.17125 6.30967  6.99333   1.000 57.96031  ? 147 ARG A CZ   1 
ATOM   2128 N NH1  . ARG A 1 147 ? 32.22842 6.70794  6.30433   1.000 60.20847  ? 147 ARG A NH1  1 
ATOM   2129 N NH2  . ARG A 1 147 ? 30.82086 6.97560  8.08991   1.000 58.86854  ? 147 ARG A NH2  1 
ATOM   2130 H H    . ARG A 1 147 ? 26.14895 6.19269  3.89837   1.000 73.69560  ? 147 ARG A H    1 
ATOM   2131 H HA   . ARG A 1 147 ? 27.58874 4.10126  2.89918   1.000 69.99664  ? 147 ARG A HA   1 
ATOM   2132 H HB2  . ARG A 1 147 ? 29.01016 5.67144  3.93732   1.000 68.08926  ? 147 ARG A HB2  1 
ATOM   2133 H HB3  . ARG A 1 147 ? 28.21134 5.44410  5.29217   1.000 68.08926  ? 147 ARG A HB3  1 
ATOM   2134 H HG2  . ARG A 1 147 ? 29.02301 3.31467  5.47954   1.000 76.28111  ? 147 ARG A HG2  1 
ATOM   2135 H HG3  . ARG A 1 147 ? 29.67618 3.39190  4.03289   1.000 76.28111  ? 147 ARG A HG3  1 
ATOM   2136 H HD2  . ARG A 1 147 ? 31.30022 3.71549  5.70610   1.000 71.12466  ? 147 ARG A HD2  1 
ATOM   2137 H HD3  . ARG A 1 147 ? 31.18126 5.00222  4.78112   1.000 71.12466  ? 147 ARG A HD3  1 
ATOM   2138 H HE   . ARG A 1 147 ? 29.76107 5.06008  7.08778   1.000 66.68445  ? 147 ARG A HE   1 
ATOM   2139 H HH11 . ARG A 1 147 ? 32.45908 6.28842  5.58991   1.000 72.25017  ? 147 ARG A HH11 1 
ATOM   2140 H HH12 . ARG A 1 147 ? 32.68485 7.38632  6.57095   1.000 72.25017  ? 147 ARG A HH12 1 
ATOM   2141 H HH21 . ARG A 1 147 ? 30.13134 6.72900  8.54085   1.000 70.64225  ? 147 ARG A HH21 1 
ATOM   2142 H HH22 . ARG A 1 147 ? 31.28379 7.65284  8.34806   1.000 70.64225  ? 147 ARG A HH22 1 
ATOM   2143 N N    . GLY A 1 148 ? 25.81134 2.67891  3.86611   1.000 62.84526  ? 148 GLY A N    1 
ATOM   2144 C CA   . GLY A 1 148 ? 24.82663 1.83915  4.51852   1.000 64.29488  ? 148 GLY A CA   1 
ATOM   2145 C C    . GLY A 1 148 ? 23.48256 2.52790  4.62243   1.000 72.10979  ? 148 GLY A C    1 
ATOM   2146 O O    . GLY A 1 148 ? 22.76713 2.65850  3.62523   1.000 75.90205  ? 148 GLY A O    1 
ATOM   2147 H H    . GLY A 1 148 ? 26.00317 2.44089  3.06228   1.000 75.41431  ? 148 GLY A H    1 
ATOM   2148 H HA2  . GLY A 1 148 ? 24.71487 1.01911  4.01262   1.000 77.15385  ? 148 GLY A HA2  1 
ATOM   2149 H HA3  . GLY A 1 148 ? 25.13075 1.61942  5.41302   1.000 77.15385  ? 148 GLY A HA3  1 
ATOM   2150 N N    . ASN A 1 149 ? 23.12793 2.97010  5.82875   1.000 72.39091  ? 149 ASN A N    1 
ATOM   2151 C CA   . ASN A 1 149 ? 21.92930 3.76505  6.05023   1.000 73.79087  ? 149 ASN A CA   1 
ATOM   2152 C C    . ASN A 1 149 ? 22.24211 5.17169  6.53809   1.000 75.03347  ? 149 ASN A C    1 
ATOM   2153 O O    . ASN A 1 149 ? 21.31149 5.93824  6.81473   1.000 72.36157  ? 149 ASN A O    1 
ATOM   2154 C CB   . ASN A 1 149 ? 21.00881 3.07316  7.06279   1.000 73.44626  ? 149 ASN A CB   1 
ATOM   2155 C CG   . ASN A 1 149 ? 19.74243 2.54116  6.42869   1.000 86.78973  ? 149 ASN A CG   1 
ATOM   2156 O OD1  . ASN A 1 149 ? 19.08305 3.23243  5.65056   1.000 83.21964  ? 149 ASN A OD1  1 
ATOM   2157 N ND2  . ASN A 1 149 ? 19.39584 1.30336  6.75382   1.000 76.84584  ? 149 ASN A ND2  1 
ATOM   2158 H H    . ASN A 1 149 ? 23.57660 2.81780  6.54646   1.000 86.86909  ? 149 ASN A H    1 
ATOM   2159 H HA   . ASN A 1 149 ? 21.44461 3.83540  5.21296   1.000 88.54904  ? 149 ASN A HA   1 
ATOM   2160 H HB2  . ASN A 1 149 ? 21.48179 2.32626  7.46196   1.000 88.13551  ? 149 ASN A HB2  1 
ATOM   2161 H HB3  . ASN A 1 149 ? 20.75652 3.71087  7.74876   1.000 88.13551  ? 149 ASN A HB3  1 
ATOM   2162 H HD21 . ASN A 1 149 ? 19.88278 0.84943  7.29829   1.000 92.21500  ? 149 ASN A HD21 1 
ATOM   2163 H HD22 . ASN A 1 149 ? 18.68411 0.95442  6.42025   1.000 92.21500  ? 149 ASN A HD22 1 
ATOM   2164 N N    . ASP A 1 150 ? 23.51759 5.53148  6.64809   1.000 70.90311  ? 150 ASP A N    1 
ATOM   2165 C CA   . ASP A 1 150 ? 23.94166 6.81522  7.18825   1.000 66.84507  ? 150 ASP A CA   1 
ATOM   2166 C C    . ASP A 1 150 ? 24.46891 7.68299  6.05604   1.000 62.48213  ? 150 ASP A C    1 
ATOM   2167 O O    . ASP A 1 150 ? 25.44781 7.31813  5.39593   1.000 58.84117  ? 150 ASP A O    1 
ATOM   2168 C CB   . ASP A 1 150 ? 25.02509 6.62602  8.25083   1.000 67.01999  ? 150 ASP A CB   1 
ATOM   2169 C CG   . ASP A 1 150 ? 24.64600 5.59746  9.29319   1.000 77.90866  ? 150 ASP A CG   1 
ATOM   2170 O OD1  . ASP A 1 150 ? 23.58802 5.76136  9.93608   1.000 87.64459  ? 150 ASP A OD1  1 
ATOM   2171 O OD2  . ASP A 1 150 ? 25.40198 4.61786  9.46303   1.000 78.73620  ? 150 ASP A OD2  1 
ATOM   2172 H H    . ASP A 1 150 ? 24.17474 5.03129  6.40819   1.000 85.08373  ? 150 ASP A H    1 
ATOM   2173 H HA   . ASP A 1 150 ? 23.17905 7.25993  7.59020   1.000 80.21409  ? 150 ASP A HA   1 
ATOM   2174 H HB2  . ASP A 1 150 ? 25.84237 6.33011  7.82026   1.000 80.42398  ? 150 ASP A HB2  1 
ATOM   2175 H HB3  . ASP A 1 150 ? 25.17554 7.47074  8.70328   1.000 80.42398  ? 150 ASP A HB3  1 
ATOM   2176 N N    . TYR A 1 151 ? 23.82666 8.82407  5.83310   1.000 62.14086  ? 151 TYR A N    1 
ATOM   2177 C CA   . TYR A 1 151 ? 24.38372 9.80638  4.91722   1.000 55.59140  ? 151 TYR A CA   1 
ATOM   2178 C C    . TYR A 1 151 ? 25.60382 10.46237 5.54908   1.000 45.33938  ? 151 TYR A C    1 
ATOM   2179 O O    . TYR A 1 151 ? 25.68328 10.63751 6.76839   1.000 48.56065  ? 151 TYR A O    1 
ATOM   2180 C CB   . TYR A 1 151 ? 23.34036 10.85515 4.54922   1.000 53.71807  ? 151 TYR A CB   1 
ATOM   2181 C CG   . TYR A 1 151 ? 22.38527 10.38097 3.47940   1.000 65.52673  ? 151 TYR A CG   1 
ATOM   2182 C CD1  . TYR A 1 151 ? 22.66762 10.57855 2.13510   1.000 66.87156  ? 151 TYR A CD1  1 
ATOM   2183 C CD2  . TYR A 1 151 ? 21.20747 9.72661  3.81218   1.000 66.13261  ? 151 TYR A CD2  1 
ATOM   2184 C CE1  . TYR A 1 151 ? 21.80234 10.14418 1.15223   1.000 70.53664  ? 151 TYR A CE1  1 
ATOM   2185 C CE2  . TYR A 1 151 ? 20.33348 9.29397  2.83573   1.000 68.13873  ? 151 TYR A CE2  1 
ATOM   2186 C CZ   . TYR A 1 151 ? 20.63755 9.49927  1.50716   1.000 70.71227  ? 151 TYR A CZ   1 
ATOM   2187 O OH   . TYR A 1 151 ? 19.77000 9.06281  0.53112   1.000 73.00640  ? 151 TYR A OH   1 
ATOM   2188 H H    . TYR A 1 151 ? 23.07920 9.04858  6.19435   1.000 74.56903  ? 151 TYR A H    1 
ATOM   2189 H HA   . TYR A 1 151 ? 24.65711 9.37482  4.09265   1.000 66.70968  ? 151 TYR A HA   1 
ATOM   2190 H HB2  . TYR A 1 151 ? 22.82150 11.07462 5.33885   1.000 64.46169  ? 151 TYR A HB2  1 
ATOM   2191 H HB3  . TYR A 1 151 ? 23.79221 11.64719 4.21846   1.000 64.46169  ? 151 TYR A HB3  1 
ATOM   2192 H HD1  . TYR A 1 151 ? 23.45413 11.01148 1.89244   1.000 80.24587  ? 151 TYR A HD1  1 
ATOM   2193 H HD2  . TYR A 1 151 ? 21.00400 9.57733  4.70729   1.000 79.35913  ? 151 TYR A HD2  1 
ATOM   2194 H HE1  . TYR A 1 151 ? 22.00402 10.28580 0.25548   1.000 84.64397  ? 151 TYR A HE1  1 
ATOM   2195 H HE2  . TYR A 1 151 ? 19.54280 8.86576  3.07311   1.000 81.76647  ? 151 TYR A HE2  1 
ATOM   2196 H HH   . TYR A 1 151 ? 19.11666 8.66893  0.88270   1.000 87.60768  ? 151 TYR A HH   1 
ATOM   2197 N N    . VAL A 1 152 ? 26.56901 10.80952 4.70301   1.000 44.48035  ? 152 VAL A N    1 
ATOM   2198 C CA   . VAL A 1 152 ? 27.83581 11.37958 5.13870   1.000 41.70693  ? 152 VAL A CA   1 
ATOM   2199 C C    . VAL A 1 152 ? 28.13281 12.60237 4.28606   1.000 42.46112  ? 152 VAL A C    1 
ATOM   2200 O O    . VAL A 1 152 ? 28.10830 12.52432 3.05257   1.000 43.99650  ? 152 VAL A O    1 
ATOM   2201 C CB   . VAL A 1 152 ? 28.99084 10.36458 5.02802   1.000 42.10802  ? 152 VAL A CB   1 
ATOM   2202 C CG1  . VAL A 1 152 ? 30.32211 11.05077 5.30475   1.000 44.61591  ? 152 VAL A CG1  1 
ATOM   2203 C CG2  . VAL A 1 152 ? 28.77562 9.19461  5.97673   1.000 51.29049  ? 152 VAL A CG2  1 
ATOM   2204 H H    . VAL A 1 152 ? 26.50975 10.72120 3.84961   1.000 53.37642  ? 152 VAL A H    1 
ATOM   2205 H HA   . VAL A 1 152 ? 27.75507 11.65857 6.06419   1.000 50.04832  ? 152 VAL A HA   1 
ATOM   2206 H HB   . VAL A 1 152 ? 29.01319 10.01018 4.12535   1.000 50.52962  ? 152 VAL A HB   1 
ATOM   2207 H HG11 . VAL A 1 152 ? 30.63343 11.47613 4.49047   1.000 53.53909  ? 152 VAL A HG11 1 
ATOM   2208 H HG12 . VAL A 1 152 ? 30.19586 11.71689 5.99848   1.000 53.53909  ? 152 VAL A HG12 1 
ATOM   2209 H HG13 . VAL A 1 152 ? 30.96514 10.38614 5.59745   1.000 53.53909  ? 152 VAL A HG13 1 
ATOM   2210 H HG21 . VAL A 1 152 ? 29.50290 8.56202  5.86809   1.000 61.54859  ? 152 VAL A HG21 1 
ATOM   2211 H HG22 . VAL A 1 152 ? 28.75890 9.52607  6.88819   1.000 61.54859  ? 152 VAL A HG22 1 
ATOM   2212 H HG23 . VAL A 1 152 ? 27.93106 8.76726  5.76462   1.000 61.54859  ? 152 VAL A HG23 1 
ATOM   2213 N N    . VAL A 1 153 ? 28.40767 13.72390 4.93803   1.000 40.72234  ? 153 VAL A N    1 
ATOM   2214 C CA   . VAL A 1 153 ? 28.93122 14.90426 4.26432   1.000 38.07715  ? 153 VAL A CA   1 
ATOM   2215 C C    . VAL A 1 153 ? 30.44755 14.87574 4.38189   1.000 38.17549  ? 153 VAL A C    1 
ATOM   2216 O O    . VAL A 1 153 ? 30.99661 14.59480 5.45420   1.000 36.10178  ? 153 VAL A O    1 
ATOM   2217 C CB   . VAL A 1 153 ? 28.34286 16.19813 4.85651   1.000 35.80817  ? 153 VAL A CB   1 
ATOM   2218 C CG1  . VAL A 1 153 ? 28.51547 16.24070 6.36586   1.000 35.78202  ? 153 VAL A CG1  1 
ATOM   2219 C CG2  . VAL A 1 153 ? 28.99499 17.41872 4.20528   1.000 35.42195  ? 153 VAL A CG2  1 
ATOM   2220 H H    . VAL A 1 153 ? 28.29766 13.82774 5.78462   1.000 48.86681  ? 153 VAL A H    1 
ATOM   2221 H HA   . VAL A 1 153 ? 28.68408 14.87872 3.32668   1.000 45.69258  ? 153 VAL A HA   1 
ATOM   2222 H HB   . VAL A 1 153 ? 27.39096 16.21867 4.67109   1.000 42.96980  ? 153 VAL A HB   1 
ATOM   2223 H HG11 . VAL A 1 153 ? 28.00943 15.51425 6.76221   1.000 42.93842  ? 153 VAL A HG11 1 
ATOM   2224 H HG12 . VAL A 1 153 ? 29.45671 16.14299 6.57896   1.000 42.93842  ? 153 VAL A HG12 1 
ATOM   2225 H HG13 . VAL A 1 153 ? 28.18786 17.09142 6.69731   1.000 42.93842  ? 153 VAL A HG13 1 
ATOM   2226 H HG21 . VAL A 1 153 ? 28.46553 18.20568 4.40840   1.000 42.50634  ? 153 VAL A HG21 1 
ATOM   2227 H HG22 . VAL A 1 153 ? 29.89228 17.52351 4.55854   1.000 42.50634  ? 153 VAL A HG22 1 
ATOM   2228 H HG23 . VAL A 1 153 ? 29.03112 17.28304 3.24549   1.000 42.50634  ? 153 VAL A HG23 1 
ATOM   2229 N N    . ILE A 1 154 ? 31.12866 15.16338 3.27346   1.000 34.54182  ? 154 ILE A N    1 
ATOM   2230 C CA   . ILE A 1 154 ? 32.58422 15.05600 3.21298   1.000 33.20821  ? 154 ILE A CA   1 
ATOM   2231 C C    . ILE A 1 154 ? 33.27408 16.40223 3.03730   1.000 32.67372  ? 154 ILE A C    1 
ATOM   2232 O O    . ILE A 1 154 ? 34.50909 16.46280 3.16351   1.000 33.84228  ? 154 ILE A O    1 
ATOM   2233 C CB   . ILE A 1 154 ? 33.03096 14.08891 2.09588   1.000 32.99093  ? 154 ILE A CB   1 
ATOM   2234 C CG1  . ILE A 1 154 ? 32.67843 14.63392 0.70932   1.000 35.45696  ? 154 ILE A CG1  1 
ATOM   2235 C CG2  . ILE A 1 154 ? 32.38449 12.71827 2.29117   1.000 34.88501  ? 154 ILE A CG2  1 
ATOM   2236 C CD1  . ILE A 1 154 ? 33.37023 13.88878 -0.42465  1.000 36.61729  ? 154 ILE A CD1  1 
ATOM   2237 H H    . ILE A 1 154 ? 30.76707 15.42474 2.53824   1.000 41.45019  ? 154 ILE A H    1 
ATOM   2238 H HA   . ILE A 1 154 ? 32.88800 14.68833 4.05763   1.000 39.84985  ? 154 ILE A HA   1 
ATOM   2239 H HB   . ILE A 1 154 ? 33.99555 14.00411 2.15296   1.000 39.58911  ? 154 ILE A HB   1 
ATOM   2240 H HG12 . ILE A 1 154 ? 31.72074 14.55660 0.57611   1.000 42.54835  ? 154 ILE A HG12 1 
ATOM   2241 H HG13 . ILE A 1 154 ? 32.94601 15.56503 0.66097   1.000 42.54835  ? 154 ILE A HG13 1 
ATOM   2242 H HG21 . ILE A 1 154 ? 32.56981 12.40702 3.19100   1.000 41.86201  ? 154 ILE A HG21 1 
ATOM   2243 H HG22 . ILE A 1 154 ? 31.42684 12.79918 2.15982   1.000 41.86201  ? 154 ILE A HG22 1 
ATOM   2244 H HG23 . ILE A 1 154 ? 32.75599 12.09876 1.64380   1.000 41.86201  ? 154 ILE A HG23 1 
ATOM   2245 H HD11 . ILE A 1 154 ? 33.05514 12.97149 -0.43827  1.000 43.94074  ? 154 ILE A HD11 1 
ATOM   2246 H HD12 . ILE A 1 154 ? 33.15726 14.32421 -1.26485  1.000 43.94074  ? 154 ILE A HD12 1 
ATOM   2247 H HD13 . ILE A 1 154 ? 34.32863 13.90715 -0.27618  1.000 43.94074  ? 154 ILE A HD13 1 
ATOM   2248 N N    . GLY A 1 155 ? 32.53754 17.46534 2.75859   1.000 32.81851  ? 155 GLY A N    1 
ATOM   2249 C CA   . GLY A 1 155 ? 33.14247 18.76366 2.54867   1.000 33.49826  ? 155 GLY A CA   1 
ATOM   2250 C C    . GLY A 1 155 ? 32.19088 19.66411 1.78606   1.000 38.53473  ? 155 GLY A C    1 
ATOM   2251 O O    . GLY A 1 155 ? 31.01598 19.34632 1.60572   1.000 33.05291  ? 155 GLY A O    1 
ATOM   2252 H H    . GLY A 1 155 ? 31.68067 17.45922 2.68552   1.000 39.38221  ? 155 GLY A H    1 
ATOM   2253 H HA2  . GLY A 1 155 ? 33.34819 19.17444 3.40298   1.000 40.19791  ? 155 GLY A HA2  1 
ATOM   2254 H HA3  . GLY A 1 155 ? 33.96208 18.66785 2.03881   1.000 40.19791  ? 155 GLY A HA3  1 
ATOM   2255 N N    . VAL A 1 156 ? 32.73316 20.79225 1.33165   1.000 34.55945  ? 156 VAL A N    1 
ATOM   2256 C CA   . VAL A 1 156 ? 31.94067 21.82910 0.68371   1.000 35.71419  ? 156 VAL A CA   1 
ATOM   2257 C C    . VAL A 1 156 ? 32.63832 22.27934 -0.59009  1.000 35.08583  ? 156 VAL A C    1 
ATOM   2258 O O    . VAL A 1 156 ? 33.87026 22.28353 -0.68004  1.000 32.76185  ? 156 VAL A O    1 
ATOM   2259 C CB   . VAL A 1 156 ? 31.70067 23.02809 1.62979   1.000 34.72530  ? 156 VAL A CB   1 
ATOM   2260 C CG1  . VAL A 1 156 ? 30.85195 22.59841 2.81280   1.000 37.27923  ? 156 VAL A CG1  1 
ATOM   2261 C CG2  . VAL A 1 156 ? 33.02294 23.60850 2.11271   1.000 36.27179  ? 156 VAL A CG2  1 
ATOM   2262 H H    . VAL A 1 156 ? 33.57034 20.98047 1.38906   1.000 41.47134  ? 156 VAL A H    1 
ATOM   2263 H HA   . VAL A 1 156 ? 31.08162 21.45783 0.42856   1.000 42.85702  ? 156 VAL A HA   1 
ATOM   2264 H HB   . VAL A 1 156 ? 31.22815 23.72091 1.14232   1.000 41.67036  ? 156 VAL A HB   1 
ATOM   2265 H HG11 . VAL A 1 156 ? 30.69823 23.36543 3.38634   1.000 44.73507  ? 156 VAL A HG11 1 
ATOM   2266 H HG12 . VAL A 1 156 ? 30.00573 22.25478 2.48613   1.000 44.73507  ? 156 VAL A HG12 1 
ATOM   2267 H HG13 . VAL A 1 156 ? 31.32222 21.90687 3.30424   1.000 44.73507  ? 156 VAL A HG13 1 
ATOM   2268 H HG21 . VAL A 1 156 ? 33.75135 23.08698 1.74078   1.000 43.52614  ? 156 VAL A HG21 1 
ATOM   2269 H HG22 . VAL A 1 156 ? 33.09056 24.52961 1.81624   1.000 43.52614  ? 156 VAL A HG22 1 
ATOM   2270 H HG23 . VAL A 1 156 ? 33.04963 23.57005 3.08158   1.000 43.52614  ? 156 VAL A HG23 1 
ATOM   2271 N N    . HIS A 1 157 ? 31.83748 22.66988 -1.57975  1.000 35.86241  ? 157 HIS A N    1 
ATOM   2272 C CA   . HIS A 1 157 ? 32.38791 23.05474 -2.87096  1.000 33.68507  ? 157 HIS A CA   1 
ATOM   2273 C C    . HIS A 1 157 ? 33.18564 24.34620 -2.74831  1.000 38.55300  ? 157 HIS A C    1 
ATOM   2274 O O    . HIS A 1 157 ? 32.70708 25.33346 -2.17745  1.000 33.86026  ? 157 HIS A O    1 
ATOM   2275 C CB   . HIS A 1 157 ? 31.27902 23.23292 -3.90271  1.000 35.09204  ? 157 HIS A CB   1 
ATOM   2276 C CG   . HIS A 1 157 ? 31.78896 23.31882 -5.30545  1.000 38.67683  ? 157 HIS A CG   1 
ATOM   2277 N ND1  . HIS A 1 157 ? 32.49275 22.29224 -5.89677  1.000 37.24196  ? 157 HIS A ND1  1 
ATOM   2278 C CD2  . HIS A 1 157 ? 31.72722 24.31152 -6.22365  1.000 36.86078  ? 157 HIS A CD2  1 
ATOM   2279 C CE1  . HIS A 1 157 ? 32.82917 22.64215 -7.12450  1.000 42.85226  ? 157 HIS A CE1  1 
ATOM   2280 N NE2  . HIS A 1 157 ? 32.37705 23.86341 -7.34798  1.000 37.45908  ? 157 HIS A NE2  1 
ATOM   2281 H H    . HIS A 1 157 ? 30.98052 22.71944 -1.52721  1.000 43.03489  ? 157 HIS A H    1 
ATOM   2282 H HA   . HIS A 1 157 ? 32.97948 22.34940 -3.17665  1.000 40.42208  ? 157 HIS A HA   1 
ATOM   2283 H HB2  . HIS A 1 157 ? 30.67619 22.47481 -3.85010  1.000 42.11045  ? 157 HIS A HB2  1 
ATOM   2284 H HB3  . HIS A 1 157 ? 30.79848 24.05296 -3.70899  1.000 42.11045  ? 157 HIS A HB3  1 
ATOM   2285 H HD2  . HIS A 1 157 ? 31.32119 25.14098 -6.11396  1.000 44.23294  ? 157 HIS A HD2  1 
ATOM   2286 H HE1  . HIS A 1 157 ? 33.30355 22.11833 -7.72905  1.000 51.42271  ? 157 HIS A HE1  1 
ATOM   2287 H HE2  . HIS A 1 157 ? 32.47389 24.30607 -8.07891  1.000 44.95090  ? 157 HIS A HE2  1 
ATOM   2288 N N    . THR A 1 158 ? 34.39465 24.34626 -3.31068  1.000 36.85549  ? 158 THR A N    1 
ATOM   2289 C CA   . THR A 1 158 ? 35.26796 25.50578 -3.20842  1.000 36.25296  ? 158 THR A CA   1 
ATOM   2290 C C    . THR A 1 158 ? 35.83466 25.92930 -4.55992  1.000 39.31608  ? 158 THR A C    1 
ATOM   2291 O O    . THR A 1 158 ? 36.11356 27.11629 -4.76561  1.000 36.58806  ? 158 THR A O    1 
ATOM   2292 C CB   . THR A 1 158 ? 36.41159 25.21938 -2.22624  1.000 37.36584  ? 158 THR A CB   1 
ATOM   2293 O OG1  . THR A 1 158 ? 37.28894 26.35005 -2.16490  1.000 41.99134  ? 158 THR A OG1  1 
ATOM   2294 C CG2  . THR A 1 158 ? 37.19689 23.99229 -2.65857  1.000 41.37998  ? 158 THR A CG2  1 
ATOM   2295 H H    . THR A 1 158 ? 34.72724 23.68853 -3.75384  1.000 44.22659  ? 158 THR A H    1 
ATOM   2296 H HA   . THR A 1 158 ? 34.74076 26.24911 -2.87612  1.000 43.50355  ? 158 THR A HA   1 
ATOM   2297 H HB   . THR A 1 158 ? 36.04336 25.04895 -1.34518  1.000 44.83901  ? 158 THR A HB   1 
ATOM   2298 H HG1  . THR A 1 158 ? 37.80252 26.35157 -2.82960  1.000 50.38960  ? 158 THR A HG1  1 
ATOM   2299 H HG21 . THR A 1 158 ? 37.95926 23.86298 -2.07292  1.000 49.65598  ? 158 THR A HG21 1 
ATOM   2300 H HG22 . THR A 1 158 ? 36.63148 23.20518 -2.61772  1.000 49.65598  ? 158 THR A HG22 1 
ATOM   2301 H HG23 . THR A 1 158 ? 37.51428 24.10503 -3.56822  1.000 49.65598  ? 158 THR A HG23 1 
ATOM   2302 N N    . ALA A 1 159 ? 36.00511 24.99450 -5.49242  1.000 37.59489  ? 159 ALA A N    1 
ATOM   2303 C CA   . ALA A 1 159 ? 36.61060 25.34966 -6.76890  1.000 39.80956  ? 159 ALA A CA   1 
ATOM   2304 C C    . ALA A 1 159 ? 36.29111 24.29719 -7.81900  1.000 38.35094  ? 159 ALA A C    1 
ATOM   2305 O O    . ALA A 1 159 ? 35.82643 23.19727 -7.51568  1.000 38.47458  ? 159 ALA A O    1 
ATOM   2306 C CB   . ALA A 1 159 ? 38.12787 25.52204 -6.63384  1.000 37.71687  ? 159 ALA A CB   1 
ATOM   2307 H H    . ALA A 1 159 ? 35.78298 24.16780 -5.40989  1.000 45.11387  ? 159 ALA A H    1 
ATOM   2308 H HA   . ALA A 1 159 ? 36.21301 26.18408 -7.06311  1.000 47.77147  ? 159 ALA A HA   1 
ATOM   2309 H HB1  . ALA A 1 159 ? 38.31019 26.20666 -5.97131  1.000 45.26024  ? 159 ALA A HB1  1 
ATOM   2310 H HB2  . ALA A 1 159 ? 38.51784 24.67902 -6.35431  1.000 45.26024  ? 159 ALA A HB2  1 
ATOM   2311 H HB3  . ALA A 1 159 ? 38.49327 25.78697 -7.49244  1.000 45.26024  ? 159 ALA A HB3  1 
ATOM   2312 N N    . ALA A 1 160 ? 36.55624 24.66325 -9.07328  1.000 42.63144  ? 160 ALA A N    1 
ATOM   2313 C CA   . ALA A 1 160 ? 36.38002 23.78308 -10.22032 1.000 43.63065  ? 160 ALA A CA   1 
ATOM   2314 C C    . ALA A 1 160 ? 37.37890 24.20841 -11.28608 1.000 48.17308  ? 160 ALA A C    1 
ATOM   2315 O O    . ALA A 1 160 ? 37.50561 25.40258 -11.56787 1.000 47.47338  ? 160 ALA A O    1 
ATOM   2316 C CB   . ALA A 1 160 ? 34.95084 23.85200 -10.76238 1.000 44.42134  ? 160 ALA A CB   1 
ATOM   2317 H H    . ALA A 1 160 ? 36.84877 25.44240 -9.28995  1.000 51.15773  ? 160 ALA A H    1 
ATOM   2318 H HA   . ALA A 1 160 ? 36.55512 22.86276 -9.96882  1.000 52.35678  ? 160 ALA A HA   1 
ATOM   2319 H HB1  . ALA A 1 160 ? 34.76746 24.75843 -11.05504 1.000 53.30561  ? 160 ALA A HB1  1 
ATOM   2320 H HB2  . ALA A 1 160 ? 34.86676 23.23965 -11.50995 1.000 53.30561  ? 160 ALA A HB2  1 
ATOM   2321 H HB3  . ALA A 1 160 ? 34.33338 23.60059 -10.05780 1.000 53.30561  ? 160 ALA A HB3  1 
ATOM   2322 N N    . ALA A 1 161 ? 38.08288 23.24239 -11.87008 1.000 58.22505  ? 161 ALA A N    1 
ATOM   2323 C CA   . ALA A 1 161 ? 39.13804 23.54561 -12.82993 1.000 64.03745  ? 161 ALA A CA   1 
ATOM   2324 C C    . ALA A 1 161 ? 38.53158 23.88863 -14.18564 1.000 69.04991  ? 161 ALA A C    1 
ATOM   2325 O O    . ALA A 1 161 ? 37.77769 23.09199 -14.75412 1.000 69.00378  ? 161 ALA A O    1 
ATOM   2326 C CB   . ALA A 1 161 ? 40.09530 22.36314 -12.96170 1.000 62.76261  ? 161 ALA A CB   1 
ATOM   2327 H H    . ALA A 1 161 ? 37.96787 22.40230 -11.72650 1.000 69.87006  ? 161 ALA A H    1 
ATOM   2328 H HA   . ALA A 1 161 ? 39.63633 24.31558 -12.51409 1.000 76.84494  ? 161 ALA A HA   1 
ATOM   2329 H HB1  . ALA A 1 161 ? 39.62102 21.61552 -13.35796 1.000 75.31513  ? 161 ALA A HB1  1 
ATOM   2330 H HB2  . ALA A 1 161 ? 40.83924 22.62071 -13.52837 1.000 75.31513  ? 161 ALA A HB2  1 
ATOM   2331 H HB3  . ALA A 1 161 ? 40.41952 22.11958 -12.08053 1.000 75.31513  ? 161 ALA A HB3  1 
ATOM   2332 N N    . ARG A 1 162 ? 38.86439 25.06914 -14.70369 1.000 73.60286  ? 162 ARG A N    1 
ATOM   2333 C CA   . ARG A 1 162 ? 38.45390 25.43593 -16.05313 1.000 81.36581  ? 162 ARG A CA   1 
ATOM   2334 C C    . ARG A 1 162 ? 39.10543 24.50109 -17.06551 1.000 79.84620  ? 162 ARG A C    1 
ATOM   2335 O O    . ARG A 1 162 ? 40.28422 24.15611 -16.94861 1.000 71.25347  ? 162 ARG A O    1 
ATOM   2336 C CB   . ARG A 1 162 ? 38.83505 26.89112 -16.33824 1.000 86.36490  ? 162 ARG A CB   1 
ATOM   2337 C CG   . ARG A 1 162 ? 38.47503 27.38953 -17.73170 1.000 92.62929  ? 162 ARG A CG   1 
ATOM   2338 C CD   . ARG A 1 162 ? 38.63844 28.90888 -17.85042 1.000 103.98912 ? 162 ARG A CD   1 
ATOM   2339 N NE   . ARG A 1 162 ? 37.76429 29.64098 -16.93895 1.000 118.83488 ? 162 ARG A NE   1 
ATOM   2340 C CZ   . ARG A 1 162 ? 38.17896 30.48126 -15.99806 1.000 114.76528 ? 162 ARG A CZ   1 
ATOM   2341 N NH1  . ARG A 1 162 ? 39.46135 30.76585 -15.83727 1.000 109.90127 ? 162 ARG A NH1  1 
ATOM   2342 N NH2  . ARG A 1 162 ? 37.28212 31.05691 -15.20229 1.000 109.90954 ? 162 ARG A NH2  1 
ATOM   2343 H H    . ARG A 1 162 ? 39.32435 25.67088 -14.29633 1.000 88.32344  ? 162 ARG A H    1 
ATOM   2344 H HA   . ARG A 1 162 ? 37.49109 25.35831 -16.14193 1.000 97.63897  ? 162 ARG A HA   1 
ATOM   2345 H HB2  . ARG A 1 162 ? 38.37743 27.45923 -15.69891 1.000 103.63788 ? 162 ARG A HB2  1 
ATOM   2346 H HB3  . ARG A 1 162 ? 39.79526 26.98270 -16.23567 1.000 103.63788 ? 162 ARG A HB3  1 
ATOM   2347 H HG2  . ARG A 1 162 ? 39.05828 26.96931 -18.38297 1.000 111.15514 ? 162 ARG A HG2  1 
ATOM   2348 H HG3  . ARG A 1 162 ? 37.55027 27.16748 -17.92248 1.000 111.15514 ? 162 ARG A HG3  1 
ATOM   2349 H HD2  . ARG A 1 162 ? 39.55564 29.14603 -17.64210 1.000 124.78694 ? 162 ARG A HD2  1 
ATOM   2350 H HD3  . ARG A 1 162 ? 38.42301 29.18079 -18.75627 1.000 124.78694 ? 162 ARG A HD3  1 
ATOM   2351 H HE   . ARG A 1 162 ? 36.91662 29.51884 -17.01724 1.000 142.60186 ? 162 ARG A HE   1 
ATOM   2352 H HH11 . ARG A 1 162 ? 40.04972 30.40341 -16.34918 1.000 131.88153 ? 162 ARG A HH11 1 
ATOM   2353 H HH12 . ARG A 1 162 ? 39.70633 31.31324 -15.22087 1.000 131.88153 ? 162 ARG A HH12 1 
ATOM   2354 H HH21 . ARG A 1 162 ? 36.44562 30.88320 -15.30069 1.000 131.89145 ? 162 ARG A HH21 1 
ATOM   2355 H HH22 . ARG A 1 162 ? 37.53872 31.60286 -14.58935 1.000 131.89145 ? 162 ARG A HH22 1 
ATOM   2356 N N    . GLY A 1 163 ? 38.32631 24.07792 -18.05754 1.000 80.96930  ? 163 GLY A N    1 
ATOM   2357 C CA   . GLY A 1 163 ? 38.84389 23.18805 -19.07838 1.000 83.63541  ? 163 GLY A CA   1 
ATOM   2358 C C    . GLY A 1 163 ? 38.86411 21.72712 -18.69411 1.000 81.83336  ? 163 GLY A C    1 
ATOM   2359 O O    . GLY A 1 163 ? 39.70538 20.97244 -19.19414 1.000 87.26424  ? 163 GLY A O    1 
ATOM   2360 H H    . GLY A 1 163 ? 37.49964 24.29288 -18.15763 1.000 97.16316  ? 163 GLY A H    1 
ATOM   2361 H HA2  . GLY A 1 163 ? 38.29734 23.27712 -19.87478 1.000 100.36250 ? 163 GLY A HA2  1 
ATOM   2362 H HA3  . GLY A 1 163 ? 39.75348 23.45149 -19.28850 1.000 100.36250 ? 163 GLY A HA3  1 
ATOM   2363 N N    . GLY A 1 164 ? 37.95911 21.30417 -17.82164 1.000 68.94009  ? 164 GLY A N    1 
ATOM   2364 C CA   . GLY A 1 164 ? 37.92033 19.92134 -17.38202 1.000 61.73896  ? 164 GLY A CA   1 
ATOM   2365 C C    . GLY A 1 164 ? 36.80543 19.73987 -16.37700 1.000 66.86698  ? 164 GLY A C    1 
ATOM   2366 O O    . GLY A 1 164 ? 36.17213 20.70381 -15.93274 1.000 67.87668  ? 164 GLY A O    1 
ATOM   2367 H H    . GLY A 1 164 ? 37.35363 21.80218 -17.46810 1.000 82.72811  ? 164 GLY A H    1 
ATOM   2368 H HA2  . GLY A 1 164 ? 37.76266 19.33600 -18.13927 1.000 74.08675  ? 164 GLY A HA2  1 
ATOM   2369 H HA3  . GLY A 1 164 ? 38.76335 19.68063 -16.96696 1.000 74.08675  ? 164 GLY A HA3  1 
ATOM   2370 N N    . ASN A 1 165 ? 36.57541 18.47832 -16.02053 1.000 65.00012  ? 165 ASN A N    1 
ATOM   2371 C CA   . ASN A 1 165 ? 35.51681 18.11205 -15.09107 1.000 62.95536  ? 165 ASN A CA   1 
ATOM   2372 C C    . ASN A 1 165 ? 35.97117 18.11934 -13.63678 1.000 57.28144  ? 165 ASN A C    1 
ATOM   2373 O O    . ASN A 1 165 ? 35.20467 17.70582 -12.75995 1.000 59.51822  ? 165 ASN A O    1 
ATOM   2374 C CB   . ASN A 1 165 ? 34.95995 16.73032 -15.44853 1.000 66.38198  ? 165 ASN A CB   1 
ATOM   2375 C CG   . ASN A 1 165 ? 34.10924 16.75405 -16.70194 1.000 81.14381  ? 165 ASN A CG   1 
ATOM   2376 O OD1  . ASN A 1 165 ? 32.99317 17.27468 -16.69520 1.000 97.98688  ? 165 ASN A OD1  1 
ATOM   2377 N ND2  . ASN A 1 165 ? 34.62837 16.18708 -17.78437 1.000 89.21755  ? 165 ASN A ND2  1 
ATOM   2378 H H    . ASN A 1 165 ? 37.02850 17.80717 -16.31013 1.000 78.00014  ? 165 ASN A H    1 
ATOM   2379 H HA   . ASN A 1 165 ? 34.79967 18.75933 -15.17836 1.000 75.54643  ? 165 ASN A HA   1 
ATOM   2380 H HB2  . ASN A 1 165 ? 35.69872 16.11970 -15.59776 1.000 79.65838  ? 165 ASN A HB2  1 
ATOM   2381 H HB3  . ASN A 1 165 ? 34.40878 16.41164 -14.71672 1.000 79.65838  ? 165 ASN A HB3  1 
ATOM   2382 H HD21 . ASN A 1 165 ? 35.41040 15.83090 -17.75015 1.000 107.06107 ? 165 ASN A HD21 1 
ATOM   2383 H HD22 . ASN A 1 165 ? 34.18262 16.17600 -18.51975 1.000 107.06107 ? 165 ASN A HD22 1 
ATOM   2384 N N    . THR A 1 166 ? 37.18556 18.58536 -13.35785 1.000 48.19368  ? 166 THR A N    1 
ATOM   2385 C CA   . THR A 1 166 ? 37.69369 18.55400 -11.99390 1.000 45.09790  ? 166 THR A CA   1 
ATOM   2386 C C    . THR A 1 166 ? 36.97202 19.58193 -11.13120 1.000 45.77763  ? 166 THR A C    1 
ATOM   2387 O O    . THR A 1 166 ? 36.83659 20.74849 -11.51242 1.000 41.17885  ? 166 THR A O    1 
ATOM   2388 C CB   . THR A 1 166 ? 39.19852 18.82280 -11.96636 1.000 41.24151  ? 166 THR A CB   1 
ATOM   2389 O OG1  . THR A 1 166 ? 39.89149 17.77734 -12.65764 1.000 52.44021  ? 166 THR A OG1  1 
ATOM   2390 C CG2  . THR A 1 166 ? 39.69587 18.89288 -10.52533 1.000 41.23619  ? 166 THR A CG2  1 
ATOM   2391 H H    . THR A 1 166 ? 37.72779 18.92079 -13.93498 1.000 57.83241  ? 166 THR A H    1 
ATOM   2392 H HA   . THR A 1 166 ? 37.53536 17.67064 -11.62580 1.000 54.11748  ? 166 THR A HA   1 
ATOM   2393 H HB   . THR A 1 166 ? 39.38458 19.67000 -12.40057 1.000 49.48981  ? 166 THR A HB   1 
ATOM   2394 H HG1  . THR A 1 166 ? 39.71812 17.03524 -12.30432 1.000 62.92825  ? 166 THR A HG1  1 
ATOM   2395 H HG21 . THR A 1 166 ? 39.28141 18.19295 -9.99691  1.000 49.48343  ? 166 THR A HG21 1 
ATOM   2396 H HG22 . THR A 1 166 ? 40.65868 18.77762 -10.50069 1.000 49.48343  ? 166 THR A HG22 1 
ATOM   2397 H HG23 . THR A 1 166 ? 39.47188 19.75377 -10.13856 1.000 49.48343  ? 166 THR A HG23 1 
ATOM   2398 N N    . VAL A 1 167 ? 36.50918 19.14064 -9.96575  1.000 40.05314  ? 167 VAL A N    1 
ATOM   2399 C CA   . VAL A 1 167 ? 35.93644 20.01289 -8.95038  1.000 40.12082  ? 167 VAL A CA   1 
ATOM   2400 C C    . VAL A 1 167 ? 36.69620 19.77204 -7.65418  1.000 36.35550  ? 167 VAL A C    1 
ATOM   2401 O O    . VAL A 1 167 ? 37.25835 18.69412 -7.43574  1.000 38.80990  ? 167 VAL A O    1 
ATOM   2402 C CB   . VAL A 1 167 ? 34.42459 19.76565 -8.76870  1.000 38.36087  ? 167 VAL A CB   1 
ATOM   2403 C CG1  . VAL A 1 167 ? 33.66679 20.24880 -9.99794  1.000 41.89865  ? 167 VAL A CG1  1 
ATOM   2404 C CG2  . VAL A 1 167 ? 34.14821 18.28978 -8.51786  1.000 41.21146  ? 167 VAL A CG2  1 
ATOM   2405 H H    . VAL A 1 167 ? 36.51701 18.31248 -9.73403  1.000 48.06376  ? 167 VAL A H    1 
ATOM   2406 H HA   . VAL A 1 167 ? 36.04907 20.94206 -9.20504  1.000 48.14498  ? 167 VAL A HA   1 
ATOM   2407 H HB   . VAL A 1 167 ? 34.11270 20.26347 -7.99682  1.000 46.03305  ? 167 VAL A HB   1 
ATOM   2408 H HG11 . VAL A 1 167 ? 32.71902 20.08845 -9.86788  1.000 50.27838  ? 167 VAL A HG11 1 
ATOM   2409 H HG12 . VAL A 1 167 ? 33.82858 21.19792 -10.11583 1.000 50.27838  ? 167 VAL A HG12 1 
ATOM   2410 H HG13 . VAL A 1 167 ? 33.98130 19.76062 -10.77490 1.000 50.27838  ? 167 VAL A HG13 1 
ATOM   2411 H HG21 . VAL A 1 167 ? 33.19620 18.16589 -8.37916  1.000 49.45375  ? 167 VAL A HG21 1 
ATOM   2412 H HG22 . VAL A 1 167 ? 34.43944 17.77844 -9.28897  1.000 49.45375  ? 167 VAL A HG22 1 
ATOM   2413 H HG23 . VAL A 1 167 ? 34.63698 18.00653 -7.72933  1.000 49.45375  ? 167 VAL A HG23 1 
ATOM   2414 N N    . ILE A 1 168 ? 36.72474 20.78583 -6.79463  1.000 33.67200  ? 168 ILE A N    1 
ATOM   2415 C CA   . ILE A 1 168 ? 37.49615 20.74499 -5.55797  1.000 32.77404  ? 168 ILE A CA   1 
ATOM   2416 C C    . ILE A 1 168 ? 36.53469 20.77220 -4.38036  1.000 33.85180  ? 168 ILE A C    1 
ATOM   2417 O O    . ILE A 1 168 ? 35.69536 21.67570 -4.27173  1.000 36.57395  ? 168 ILE A O    1 
ATOM   2418 C CB   . ILE A 1 168 ? 38.49624 21.90975 -5.47331  1.000 32.23672  ? 168 ILE A CB   1 
ATOM   2419 C CG1  . ILE A 1 168 ? 39.38957 21.95627 -6.71616  1.000 39.19612  ? 168 ILE A CG1  1 
ATOM   2420 C CG2  . ILE A 1 168 ? 39.35343 21.77195 -4.22258  1.000 34.35912  ? 168 ILE A CG2  1 
ATOM   2421 C CD1  . ILE A 1 168 ? 40.13655 20.65644 -7.00421  1.000 38.15724  ? 168 ILE A CD1  1 
ATOM   2422 H H    . ILE A 1 168 ? 36.29615 21.52255 -6.90939  1.000 40.40640  ? 168 ILE A H    1 
ATOM   2423 H HA   . ILE A 1 168 ? 37.99190 19.91184 -5.52662  1.000 39.32884  ? 168 ILE A HA   1 
ATOM   2424 H HB   . ILE A 1 168 ? 37.99129 22.73675 -5.42863  1.000 38.68407  ? 168 ILE A HB   1 
ATOM   2425 H HG12 . ILE A 1 168 ? 38.83612 22.15382 -7.48788  1.000 47.03534  ? 168 ILE A HG12 1 
ATOM   2426 H HG13 . ILE A 1 168 ? 40.05181 22.65465 -6.59532  1.000 47.03534  ? 168 ILE A HG13 1 
ATOM   2427 H HG21 . ILE A 1 168 ? 39.76999 20.89595 -4.22016  1.000 41.23094  ? 168 ILE A HG21 1 
ATOM   2428 H HG22 . ILE A 1 168 ? 40.03487 22.46225 -4.22912  1.000 41.23094  ? 168 ILE A HG22 1 
ATOM   2429 H HG23 . ILE A 1 168 ? 38.78884 21.87191 -3.44019  1.000 41.23094  ? 168 ILE A HG23 1 
ATOM   2430 H HD11 . ILE A 1 168 ? 40.63667 20.39790 -6.21430  1.000 45.78869  ? 168 ILE A HD11 1 
ATOM   2431 H HD12 . ILE A 1 168 ? 39.49358 19.96593 -7.22932  1.000 45.78869  ? 168 ILE A HD12 1 
ATOM   2432 H HD13 . ILE A 1 168 ? 40.74299 20.79881 -7.74775  1.000 45.78869  ? 168 ILE A HD13 1 
ATOM   2433 N N    . CYS A 1 169 ? 36.66766 19.79071 -3.49234  1.000 36.38092  ? 169 CYS A N    1 
ATOM   2434 C CA   . CYS A 1 169 ? 35.86132 19.69036 -2.28079  1.000 37.01182  ? 169 CYS A CA   1 
ATOM   2435 C C    . CYS A 1 169 ? 36.73250 20.06526 -1.08785  1.000 35.39021  ? 169 CYS A C    1 
ATOM   2436 O O    . CYS A 1 169 ? 37.67392 19.33990 -0.74719  1.000 32.85628  ? 169 CYS A O    1 
ATOM   2437 C CB   . CYS A 1 169 ? 35.29596 18.28039 -2.12015  1.000 39.60906  ? 169 CYS A CB   1 
ATOM   2438 S SG   . CYS A 1 169 ? 34.45649 17.98973 -0.54626  1.000 39.07136  ? 169 CYS A SG   1 
ATOM   2439 H H    . CYS A 1 169 ? 37.23691 19.15119 -3.57343  1.000 43.65711  ? 169 CYS A H    1 
ATOM   2440 H HA   . CYS A 1 169 ? 35.12347 20.31779 -2.33377  1.000 44.41419  ? 169 CYS A HA   1 
ATOM   2441 H HB2  . CYS A 1 169 ? 34.65356 18.12187 -2.82944  1.000 47.53087  ? 169 CYS A HB2  1 
ATOM   2442 H HB3  . CYS A 1 169 ? 36.02591 17.64494 -2.18554  1.000 47.53087  ? 169 CYS A HB3  1 
ATOM   2443 H HG   . CYS A 1 169 ? 33.56567 18.78469 -0.42597  1.000 46.88564  ? 169 CYS A HG   1 
ATOM   2444 N N    . ALA A 1 170 ? 36.41611 21.19077 -0.45221  1.000 33.95482  ? 170 ALA A N    1 
ATOM   2445 C CA   . ALA A 1 170 ? 37.14870 21.60363 0.73752   1.000 34.60716  ? 170 ALA A CA   1 
ATOM   2446 C C    . ALA A 1 170 ? 36.78872 20.69712 1.90704   1.000 32.31094  ? 170 ALA A C    1 
ATOM   2447 O O    . ALA A 1 170 ? 35.60926 20.51088 2.22171   1.000 32.86133  ? 170 ALA A O    1 
ATOM   2448 C CB   . ALA A 1 170 ? 36.83660 23.05815 1.08115   1.000 34.31928  ? 170 ALA A CB   1 
ATOM   2449 H H    . ALA A 1 170 ? 35.78689 21.72735 -0.68838  1.000 40.74579  ? 170 ALA A H    1 
ATOM   2450 H HA   . ALA A 1 170 ? 38.10157 21.53386 0.57003   1.000 41.52859  ? 170 ALA A HA   1 
ATOM   2451 H HB1  . ALA A 1 170 ? 37.10184 23.62215 0.33788   1.000 41.18313  ? 170 ALA A HB1  1 
ATOM   2452 H HB2  . ALA A 1 170 ? 35.88400 23.14754 1.24071   1.000 41.18313  ? 170 ALA A HB2  1 
ATOM   2453 H HB3  . ALA A 1 170 ? 37.33029 23.30730 1.87807   1.000 41.18313  ? 170 ALA A HB3  1 
ATOM   2454 N N    . THR A 1 171 ? 37.80524 20.13046 2.54798   1.000 33.78479  ? 171 THR A N    1 
ATOM   2455 C CA   . THR A 1 171 ? 37.61732 19.25976 3.69483   1.000 36.94229  ? 171 THR A CA   1 
ATOM   2456 C C    . THR A 1 171 ? 38.24493 19.89032 4.93072   1.000 41.75309  ? 171 THR A C    1 
ATOM   2457 O O    . THR A 1 171 ? 39.04983 20.82204 4.84238   1.000 41.33750  ? 171 THR A O    1 
ATOM   2458 C CB   . THR A 1 171 ? 38.23324 17.87324 3.45965   1.000 37.53491  ? 171 THR A CB   1 
ATOM   2459 O OG1  . THR A 1 171 ? 39.65885 17.98977 3.37118   1.000 42.89568  ? 171 THR A OG1  1 
ATOM   2460 C CG2  . THR A 1 171 ? 37.69992 17.25730 2.17606   1.000 35.58155  ? 171 THR A CG2  1 
ATOM   2461 H H    . THR A 1 171 ? 38.62991 20.23975 2.32986   1.000 40.54175  ? 171 THR A H    1 
ATOM   2462 H HA   . THR A 1 171 ? 36.66695 19.14650 3.85254   1.000 44.33075  ? 171 THR A HA   1 
ATOM   2463 H HB   . THR A 1 171 ? 37.99943 17.28903 4.19785   1.000 45.04189  ? 171 THR A HB   1 
ATOM   2464 H HG1  . THR A 1 171 ? 39.99943 17.23793 3.21518   1.000 51.47482  ? 171 THR A HG1  1 
ATOM   2465 H HG21 . THR A 1 171 ? 36.73465 17.17451 2.22390   1.000 42.69786  ? 171 THR A HG21 1 
ATOM   2466 H HG22 . THR A 1 171 ? 37.93068 17.81739 1.41847   1.000 42.69786  ? 171 THR A HG22 1 
ATOM   2467 H HG23 . THR A 1 171 ? 38.08531 16.37677 2.04552   1.000 42.69786  ? 171 THR A HG23 1 
ATOM   2468 N N    . GLN A 1 172 ? 37.86856 19.36144 6.08928   1.000 43.56301  ? 172 GLN A N    1 
ATOM   2469 C CA   . GLN A 1 172 ? 38.39320 19.80813 7.37102   1.000 54.04877  ? 172 GLN A CA   1 
ATOM   2470 C C    . GLN A 1 172 ? 39.46688 18.83892 7.84525   1.000 61.49321  ? 172 GLN A C    1 
ATOM   2471 O O    . GLN A 1 172 ? 39.28977 17.61944 7.77506   1.000 65.80498  ? 172 GLN A O    1 
ATOM   2472 C CB   . GLN A 1 172 ? 37.27341 19.89982 8.41002   1.000 57.34776  ? 172 GLN A CB   1 
ATOM   2473 C CG   . GLN A 1 172 ? 37.46226 21.00113 9.44424   1.000 65.49823  ? 172 GLN A CG   1 
ATOM   2474 C CD   . GLN A 1 172 ? 36.49095 20.90914 10.61893  1.000 69.88762  ? 172 GLN A CD   1 
ATOM   2475 O OE1  . GLN A 1 172 ? 36.40035 21.83377 11.42635  1.000 74.77299  ? 172 GLN A OE1  1 
ATOM   2476 N NE2  . GLN A 1 172 ? 35.77306 19.79264 10.72258  1.000 69.10295  ? 172 GLN A NE2  1 
ATOM   2477 H H    . GLN A 1 172 ? 37.29447 18.72494 6.15925   1.000 52.27561  ? 172 GLN A H    1 
ATOM   2478 H HA   . GLN A 1 172 ? 38.79105 20.68787 7.27787   1.000 64.85853  ? 172 GLN A HA   1 
ATOM   2479 H HB2  . GLN A 1 172 ? 36.43722 20.07073 7.94905   1.000 68.81731  ? 172 GLN A HB2  1 
ATOM   2480 H HB3  . GLN A 1 172 ? 37.22344 19.05608 8.88595   1.000 68.81731  ? 172 GLN A HB3  1 
ATOM   2481 H HG2  . GLN A 1 172 ? 38.36316 20.94564 9.79949   1.000 78.59788  ? 172 GLN A HG2  1 
ATOM   2482 H HG3  . GLN A 1 172 ? 37.32737 21.86029 9.01466   1.000 78.59788  ? 172 GLN A HG3  1 
ATOM   2483 H HE21 . GLN A 1 172 ? 35.86845 19.16471 10.14275  1.000 82.92354  ? 172 GLN A HE21 1 
ATOM   2484 H HE22 . GLN A 1 172 ? 35.21397 19.69939 11.36936  1.000 82.92354  ? 172 GLN A HE22 1 
ATOM   2485 N N    . GLY A 1 173 ? 40.57720 19.38391 8.32718   1.000 69.78297  ? 173 GLY A N    1 
ATOM   2486 C CA   . GLY A 1 173 ? 41.67348 18.56386 8.78831   1.000 75.98546  ? 173 GLY A CA   1 
ATOM   2487 C C    . GLY A 1 173 ? 41.34596 17.85098 10.08968  1.000 83.94443  ? 173 GLY A C    1 
ATOM   2488 O O    . GLY A 1 173 ? 40.20111 17.77305 10.53820  1.000 74.26279  ? 173 GLY A O    1 
ATOM   2489 H H    . GLY A 1 173 ? 40.71509 20.23003 8.39546   1.000 83.73957  ? 173 GLY A H    1 
ATOM   2490 H HA2  . GLY A 1 173 ? 41.88114 17.89579 8.11641   1.000 91.18256  ? 173 GLY A HA2  1 
ATOM   2491 H HA3  . GLY A 1 173 ? 42.45454 19.12086 8.93180   1.000 91.18256  ? 173 GLY A HA3  1 
ATOM   2492 N N    . SER A 1 174 ? 42.39690 17.31529 10.70362  1.000 99.14612  ? 174 SER A N    1 
ATOM   2493 C CA   . SER A 1 174 ? 42.27359 16.63306 11.98641  1.000 107.72816 ? 174 SER A CA   1 
ATOM   2494 C C    . SER A 1 174 ? 42.24578 17.64778 13.12589  1.000 113.62302 ? 174 SER A C    1 
ATOM   2495 O O    . SER A 1 174 ? 41.20985 17.86425 13.75443  1.000 116.31187 ? 174 SER A O    1 
ATOM   2496 C CB   . SER A 1 174 ? 43.42606 15.64831 12.18644  1.000 112.07176 ? 174 SER A CB   1 
ATOM   2497 O OG   . SER A 1 174 ? 44.66752 16.32530 12.27331  1.000 119.30908 ? 174 SER A OG   1 
ATOM   2498 H H    . SER A 1 174 ? 43.19924 17.33403 10.39459  1.000 118.97534 ? 174 SER A H    1 
ATOM   2499 H HA   . SER A 1 174 ? 41.44648 16.12661 12.00353  1.000 129.27379 ? 174 SER A HA   1 
ATOM   2500 H HB2  . SER A 1 174 ? 43.27885 15.15457 13.00830  1.000 134.48612 ? 174 SER A HB2  1 
ATOM   2501 H HB3  . SER A 1 174 ? 43.45266 15.03799 11.43298  1.000 134.48612 ? 174 SER A HB3  1 
ATOM   2502 H HG   . SER A 1 174 ? 45.29048 15.77107 12.37506  1.000 143.17090 ? 174 SER A HG   1 
HETATM 2503 C C01  . AG7 B 2 .   ? 38.05168 28.61004 -9.03832  1.000 39.13730  ? 201 AG7 A C01  1 
HETATM 2504 C C02  . AG7 B 2 .   ? 38.45577 29.50187 -7.89241  1.000 39.62782  ? 201 AG7 A C02  1 
HETATM 2505 O O03  . AG7 B 2 .   ? 37.06098 27.90352 -9.02568  1.000 35.74677  ? 201 AG7 A O03  1 
HETATM 2506 C C04  . AG7 B 2 .   ? 37.46906 29.52443 -6.75999  1.000 40.29362  ? 201 AG7 A C04  1 
HETATM 2507 C C05  . AG7 B 2 .   ? 37.87394 30.51336 -5.65810  1.000 40.95720  ? 201 AG7 A C05  1 
HETATM 2508 C C06  . AG7 B 2 .   ? 39.06847 30.07655 -4.86952  1.000 38.92611  ? 201 AG7 A C06  1 
HETATM 2509 C C07  . AG7 B 2 .   ? 39.01064 28.94933 -4.05458  1.000 37.14742  ? 201 AG7 A C07  1 
HETATM 2510 C C08  . AG7 B 2 .   ? 40.11235 28.53746 -3.32699  1.000 38.44551  ? 201 AG7 A C08  1 
HETATM 2511 C C09  . AG7 B 2 .   ? 41.27389 29.27640 -3.42303  1.000 37.33960  ? 201 AG7 A C09  1 
HETATM 2512 C C10  . AG7 B 2 .   ? 41.37471 30.39924 -4.21563  1.000 40.57747  ? 201 AG7 A C10  1 
HETATM 2513 C C11  . AG7 B 2 .   ? 40.25818 30.79240 -4.93832  1.000 41.05851  ? 201 AG7 A C11  1 
HETATM 2514 N N12  . AG7 B 2 .   ? 35.08435 29.42284 -6.76303  1.000 38.85759  ? 201 AG7 A N12  1 
HETATM 2515 C C13  . AG7 B 2 .   ? 33.69551 29.73142 -7.05535  1.000 46.11614  ? 201 AG7 A C13  1 
HETATM 2516 C C14  . AG7 B 2 .   ? 33.07388 28.45264 -7.59726  1.000 43.05655  ? 201 AG7 A C14  1 
HETATM 2517 C C15  . AG7 B 2 .   ? 33.74291 27.89247 -8.88092  1.000 42.00225  ? 201 AG7 A C15  1 
HETATM 2518 C C16  . AG7 B 2 .   ? 33.06168 26.72056 -9.58306  1.000 44.19933  ? 201 AG7 A C16  1 
HETATM 2519 N N17  . AG7 B 2 .   ? 33.06908 26.96270 -10.90731 1.000 42.53961  ? 201 AG7 A N17  1 
HETATM 2520 O O18  . AG7 B 2 .   ? 32.62046 25.71570 -9.05029  1.000 47.39797  ? 201 AG7 A O18  1 
HETATM 2521 C C19  . AG7 B 2 .   ? 33.14318 30.31882 -5.74966  1.000 45.35123  ? 201 AG7 A C19  1 
HETATM 2522 C C20  . AG7 B 2 .   ? 33.54077 31.74434 -5.36331  1.000 48.76865  ? 201 AG7 A C20  1 
HETATM 2523 C C21  . AG7 B 2 .   ? 33.11990 32.83110 -6.30832  1.000 46.25556  ? 201 AG7 A C21  1 
HETATM 2524 O O22  . AG7 B 2 .   ? 33.97578 33.84617 -6.22937  1.000 63.04256  ? 201 AG7 A O22  1 
HETATM 2525 O O23  . AG7 B 2 .   ? 32.15755 32.79661 -7.03219  1.000 51.61296  ? 201 AG7 A O23  1 
HETATM 2526 C C47  . AG7 B 2 .   ? 36.13816 30.03490 -7.26910  1.000 42.15960  ? 201 AG7 A C47  1 
HETATM 2527 O O48  . AG7 B 2 .   ? 36.07009 30.95496 -8.06598  1.000 44.91086  ? 201 AG7 A O48  1 
HETATM 2528 C C50  . AG7 B 2 .   ? 33.66593 34.95724 -5.36424  1.000 71.76104  ? 201 AG7 A C50  1 
HETATM 2529 C C53  . AG7 B 2 .   ? 34.00292 34.60460 -3.92549  1.000 53.07509  ? 201 AG7 A C53  1 
HETATM 2530 C C57  . AG7 B 2 .   ? 39.02387 28.62115 -10.23590 1.000 42.22445  ? 201 AG7 A C57  1 
HETATM 2531 N N58  . AG7 B 2 .   ? 39.48253 27.24625 -10.18566 1.000 40.22859  ? 201 AG7 A N58  1 
HETATM 2532 C C59  . AG7 B 2 .   ? 40.75268 26.93011 -9.89864  1.000 36.62949  ? 201 AG7 A C59  1 
HETATM 2533 O O60  . AG7 B 2 .   ? 41.62456 27.74839 -9.67404  1.000 36.17154  ? 201 AG7 A O60  1 
HETATM 2534 C C78  . AG7 B 2 .   ? 38.45655 29.14557 -11.53795 1.000 52.35438  ? 201 AG7 A C78  1 
HETATM 2535 C C81  . AG7 B 2 .   ? 37.77635 28.07761 -12.36250 1.000 57.21035  ? 201 AG7 A C81  1 
HETATM 2536 F F1   . AG7 B 2 .   ? 42.34071 28.87795 -2.71709  1.000 42.47436  ? 201 AG7 A F1   1 
HETATM 2537 C C82  . AG7 B 2 .   ? 37.48155 30.30980 -11.26411 1.000 44.97966  ? 201 AG7 A C82  1 
HETATM 2538 C C83  . AG7 B 2 .   ? 33.66290 28.21947 -11.30432 1.000 43.63438  ? 201 AG7 A C83  1 
HETATM 2539 C C84  . AG7 B 2 .   ? 33.71206 28.98245 -9.97558  1.000 40.36473  ? 201 AG7 A C84  1 
HETATM 2540 C C1   . AG7 B 2 .   ? 41.09811 25.48863 -9.84030  1.000 44.03649  ? 201 AG7 A C1   1 
HETATM 2541 C C2   . AG7 B 2 .   ? 42.40799 24.98457 -9.72879  1.000 49.38531  ? 201 AG7 A C2   1 
HETATM 2542 C C3   . AG7 B 2 .   ? 42.22950 23.64563 -9.68238  1.000 51.55256  ? 201 AG7 A C3   1 
HETATM 2543 O O4   . AG7 B 2 .   ? 40.91125 23.38448 -9.74262  1.000 47.88724  ? 201 AG7 A O4   1 
HETATM 2544 N N5   . AG7 B 2 .   ? 40.20861 24.53608 -9.83115  1.000 46.57232  ? 201 AG7 A N5   1 
HETATM 2545 C C4   . AG7 B 2 .   ? 43.18411 22.51464 -9.57541  1.000 47.45193  ? 201 AG7 A C4   1 
HETATM 2546 H H2   . AG7 B 2 .   ? 39.32351 29.22112 -7.56208  1.000 47.55338  ? 201 AG7 A H2   1 
HETATM 2547 H H3   . AG7 B 2 .   ? 38.59099 30.40339 -8.22390  1.000 47.55338  ? 201 AG7 A H3   1 
HETATM 2548 H H27  . AG7 B 2 .   ? 37.43314 28.61737 -6.41813  1.000 48.35235  ? 201 AG7 A H27  1 
HETATM 2549 H H28  . AG7 B 2 .   ? 37.11971 30.64071 -5.06159  1.000 49.14864  ? 201 AG7 A H28  1 
HETATM 2550 H H29  . AG7 B 2 .   ? 38.05050 31.37650 -6.06396  1.000 49.14864  ? 201 AG7 A H29  1 
HETATM 2551 H H30  . AG7 B 2 .   ? 38.22483 28.45624 -3.98922  1.000 44.57690  ? 201 AG7 A H30  1 
HETATM 2552 H H31  . AG7 B 2 .   ? 40.07444 27.78208 -2.78583  1.000 46.13462  ? 201 AG7 A H31  1 
HETATM 2553 H H33  . AG7 B 2 .   ? 42.16957 30.87960 -4.26418  1.000 48.69296  ? 201 AG7 A H33  1 
HETATM 2554 H H34  . AG7 B 2 .   ? 40.31120 31.54872 -5.47689  1.000 49.27021  ? 201 AG7 A H34  1 
HETATM 2555 H H49  . AG7 B 2 .   ? 35.22536 28.78102 -6.20824  1.000 46.62911  ? 201 AG7 A H49  1 
HETATM 2556 H H91  . AG7 B 2 .   ? 33.52686 30.38674 -7.75033  1.000 55.33937  ? 201 AG7 A H91  1 
HETATM 2557 H H35  . AG7 B 2 .   ? 32.13261 28.61690 -7.76440  1.000 51.66786  ? 201 AG7 A H35  1 
HETATM 2558 H H36  . AG7 B 2 .   ? 33.09607 27.78120 -6.89757  1.000 51.66786  ? 201 AG7 A H36  1 
HETATM 2559 H H94  . AG7 B 2 .   ? 34.62839 27.58148 -8.63576  1.000 50.40269  ? 201 AG7 A H94  1 
HETATM 2560 H H39  . AG7 B 2 .   ? 32.74198 26.40541 -11.47480 1.000 51.04753  ? 201 AG7 A H39  1 
HETATM 2561 H H191 . AG7 B 2 .   ? 32.17581 30.27212 -5.80366  1.000 54.42147  ? 201 AG7 A H191 1 
HETATM 2562 H H192 . AG7 B 2 .   ? 33.40790 29.71990 -5.03403  1.000 54.42147  ? 201 AG7 A H192 1 
HETATM 2563 H H41  . AG7 B 2 .   ? 33.17749 31.97689 -4.49449  1.000 58.52238  ? 201 AG7 A H41  1 
HETATM 2564 H H42  . AG7 B 2 .   ? 34.50343 31.81697 -5.26891  1.000 58.52238  ? 201 AG7 A H42  1 
HETATM 2565 H H51  . AG7 B 2 .   ? 32.72356 35.17092 -5.44893  1.000 86.11324  ? 201 AG7 A H51  1 
HETATM 2566 H H52  . AG7 B 2 .   ? 34.17353 35.73253 -5.65090  1.000 86.11324  ? 201 AG7 A H52  1 
HETATM 2567 H H53  . AG7 B 2 .   ? 34.66277 35.21094 -3.55422  1.000 63.69010  ? 201 AG7 A H53  1 
HETATM 2568 H H54  . AG7 B 2 .   ? 34.36379 33.70717 -3.85277  1.000 63.69010  ? 201 AG7 A H54  1 
HETATM 2569 H H56  . AG7 B 2 .   ? 33.21991 34.64692 -3.35452  1.000 63.69010  ? 201 AG7 A H56  1 
HETATM 2570 H H77  . AG7 B 2 .   ? 39.80402 29.17920 -10.09152 1.000 50.66934  ? 201 AG7 A H77  1 
HETATM 2571 H H61  . AG7 B 2 .   ? 38.91827 26.61730 -10.34575 1.000 48.27431  ? 201 AG7 A H61  1 
HETATM 2572 H H79  . AG7 B 2 .   ? 39.21154 29.45375 -12.06322 1.000 62.82526  ? 201 AG7 A H79  1 
HETATM 2573 H H82  . AG7 B 2 .   ? 37.02603 27.69797 -11.87898 1.000 68.65242  ? 201 AG7 A H82  1 
HETATM 2574 H H84  . AG7 B 2 .   ? 38.39579 27.36149 -12.57314 1.000 68.65242  ? 201 AG7 A H84  1 
HETATM 2575 H H85  . AG7 B 2 .   ? 37.44503 28.44769 -13.19567 1.000 68.65242  ? 201 AG7 A H85  1 
HETATM 2576 H H86  . AG7 B 2 .   ? 37.24799 30.79330 -12.07193 1.000 53.97559  ? 201 AG7 A H86  1 
HETATM 2577 H H87  . AG7 B 2 .   ? 37.85074 30.96361 -10.65000 1.000 53.97559  ? 201 AG7 A H87  1 
HETATM 2578 H H88  . AG7 B 2 .   ? 36.64643 30.00773 -10.87393 1.000 53.97559  ? 201 AG7 A H88  1 
HETATM 2579 H H89  . AG7 B 2 .   ? 33.11738 28.66717 -11.96981 1.000 52.36126  ? 201 AG7 A H89  1 
HETATM 2580 H H90  . AG7 B 2 .   ? 34.54370 28.08260 -11.68691 1.000 52.36126  ? 201 AG7 A H90  1 
HETATM 2581 H H92  . AG7 B 2 .   ? 32.93384 29.55375 -9.88127  1.000 48.43768  ? 201 AG7 A H92  1 
HETATM 2582 H H93  . AG7 B 2 .   ? 34.50122 29.54495 -9.93420  1.000 48.43768  ? 201 AG7 A H93  1 
HETATM 2583 H H8   . AG7 B 2 .   ? 43.20855 25.45664 -9.69478  1.000 59.26237  ? 201 AG7 A H8   1 
HETATM 2584 H H5   . AG7 B 2 .   ? 43.03814 22.00846 -8.76093  1.000 56.94232  ? 201 AG7 A H5   1 
HETATM 2585 H H6   . AG7 B 2 .   ? 44.10145 22.82977 -9.56637  1.000 56.94232  ? 201 AG7 A H6   1 
HETATM 2586 H H7   . AG7 B 2 .   ? 43.08942 21.90399 -10.32310 1.000 56.94232  ? 201 AG7 A H7   1 
HETATM 2587 O O    . HOH C 3 .   ? 30.36318 36.44820 0.92407   1.000 49.43587  ? 301 HOH A O    1 
HETATM 2588 O O    . HOH C 3 .   ? 35.65983 24.35280 -14.67385 1.000 60.38782  ? 302 HOH A O    1 
HETATM 2589 O O    . HOH C 3 .   ? 33.81451 9.60935  4.08777   1.000 39.11004  ? 303 HOH A O    1 
HETATM 2590 O O    . HOH C 3 .   ? 24.16116 28.18138 -6.69927  1.000 33.60738  ? 304 HOH A O    1 
HETATM 2591 O O    . HOH C 3 .   ? 45.37368 9.93651  -4.69294  1.000 43.96652  ? 305 HOH A O    1 
HETATM 2592 O O    . HOH C 3 .   ? 40.59642 23.71479 3.02893   1.000 31.95975  ? 306 HOH A O    1 
HETATM 2593 O O    . HOH C 3 .   ? 46.98542 22.79834 -7.46266  1.000 30.94032  ? 307 HOH A O    1 
HETATM 2594 O O    . HOH C 3 .   ? 17.53894 26.04272 20.57133  1.000 56.45839  ? 308 HOH A O    1 
HETATM 2595 O O    . HOH C 3 .   ? 27.19417 41.94369 16.47803  1.000 46.21110  ? 309 HOH A O    1 
HETATM 2596 O O    . HOH C 3 .   ? 32.96111 9.22552  11.19674  1.000 47.46514  ? 310 HOH A O    1 
HETATM 2597 O O    . HOH C 3 .   ? 38.08499 11.17624 -9.45434  1.000 39.80779  ? 311 HOH A O    1 
HETATM 2598 O O    . HOH C 3 .   ? 17.67939 15.23714 10.18450  1.000 50.76939  ? 312 HOH A O    1 
HETATM 2599 O O    . HOH C 3 .   ? 26.62097 15.68901 13.83324  1.000 47.60810  ? 313 HOH A O    1 
HETATM 2600 O O    . HOH C 3 .   ? 14.10970 19.90519 1.44664   1.000 41.78447  ? 314 HOH A O    1 
HETATM 2601 O O    . HOH C 3 .   ? 41.51311 21.81492 5.43458   1.000 39.67761  ? 315 HOH A O    1 
HETATM 2602 O O    . HOH C 3 .   ? 29.70602 30.92951 -4.38670  1.000 38.98924  ? 316 HOH A O    1 
HETATM 2603 O O    . HOH C 3 .   ? 30.94044 33.46223 -4.19563  1.000 42.99668  ? 317 HOH A O    1 
HETATM 2604 O O    . HOH C 3 .   ? 33.02658 35.00568 15.80890  1.000 37.72326  ? 318 HOH A O    1 
HETATM 2605 O O    . HOH C 3 .   ? 23.68281 32.44466 -2.57150  1.000 40.82449  ? 319 HOH A O    1 
HETATM 2606 O O    . HOH C 3 .   ? 35.56891 17.37680 5.79621   1.000 32.29686  ? 320 HOH A O    1 
HETATM 2607 O O    . HOH C 3 .   ? 34.23610 6.21815  8.95829   1.000 51.96484  ? 321 HOH A O    1 
HETATM 2608 O O    . HOH C 3 .   ? 24.55651 31.50551 -4.99894  1.000 42.20161  ? 322 HOH A O    1 
HETATM 2609 O O    . HOH C 3 .   ? 18.73339 14.44858 6.98772   1.000 58.46430  ? 323 HOH A O    1 
HETATM 2610 O O    . HOH C 3 .   ? 34.64787 35.68979 2.60915   1.000 38.86861  ? 324 HOH A O    1 
HETATM 2611 O O    . HOH C 3 .   ? 41.55331 30.36403 5.62020   1.000 46.00879  ? 325 HOH A O    1 
HETATM 2612 O O    . HOH C 3 .   ? 29.31404 41.20560 4.81673   1.000 41.75993  ? 326 HOH A O    1 
HETATM 2613 O O    . HOH C 3 .   ? 42.27662 16.36701 2.26496   1.000 45.87046  ? 327 HOH A O    1 
HETATM 2614 O O    . HOH C 3 .   ? 38.29399 39.70409 5.58365   1.000 35.10350  ? 328 HOH A O    1 
HETATM 2615 O O    . HOH C 3 .   ? 23.52518 35.48155 3.88072   1.000 37.83177  ? 329 HOH A O    1 
HETATM 2616 O O    . HOH C 3 .   ? 18.14388 10.42633 -5.03515  1.000 72.17525  ? 330 HOH A O    1 
HETATM 2617 O O    . HOH C 3 .   ? 23.12849 30.08268 -7.94604  1.000 40.02705  ? 331 HOH A O    1 
HETATM 2618 O O    . HOH C 3 .   ? 34.76206 32.98639 16.24574  1.000 33.11166  ? 332 HOH A O    1 
HETATM 2619 O O    . HOH C 3 .   ? 38.45595 8.42927  -8.66245  1.000 43.80127  ? 333 HOH A O    1 
HETATM 2620 O O    . HOH C 3 .   ? 32.42926 39.09112 2.56770   1.000 49.86367  ? 334 HOH A O    1 
HETATM 2621 O O    . HOH C 3 .   ? 22.21499 34.78779 8.43793   1.000 46.78640  ? 335 HOH A O    1 
HETATM 2622 O O    . HOH C 3 .   ? 33.63599 37.03411 0.96129   1.000 44.66048  ? 336 HOH A O    1 
HETATM 2623 O O    . HOH C 3 .   ? 45.675   15.392   2.621     1.000 47.18268  ? 337 HOH A O    1 
HETATM 2624 O O    . HOH C 3 .   ? 23.79418 30.80059 -10.14275 1.000 53.29735  ? 338 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . ALA A 1   ? 1.02442 0.74689 1.14331 -0.26207 -0.13444 -0.19158 1   ALA A N   
2    C CA  . ALA A 1   ? 1.08563 0.81531 1.25431 -0.24909 -0.09585 -0.15199 1   ALA A CA  
3    C C   . ALA A 1   ? 0.99920 0.79073 1.25785 -0.27240 -0.10548 -0.14212 1   ALA A C   
4    O O   . ALA A 1   ? 1.01554 0.86202 1.30055 -0.28712 -0.14662 -0.15821 1   ALA A O   
5    C CB  . ALA A 1   ? 0.90346 0.65454 1.03476 -0.20703 -0.08275 -0.12019 1   ALA A CB  
13   N N   . PRO A 2   ? 1.01412 0.79849 1.31945 -0.27404 -0.06699 -0.11502 2   PRO A N   
14   C CA  . PRO A 2   ? 0.85516 0.69929 1.25164 -0.29743 -0.06626 -0.10598 2   PRO A CA  
15   C C   . PRO A 2   ? 0.82163 0.74504 1.23445 -0.27241 -0.08291 -0.08641 2   PRO A C   
16   O O   . PRO A 2   ? 0.76245 0.68466 1.11731 -0.23653 -0.08189 -0.07008 2   PRO A O   
17   C CB  . PRO A 2   ? 0.85641 0.65672 1.27309 -0.29926 -0.01191 -0.07666 2   PRO A CB  
18   C CG  . PRO A 2   ? 1.02104 0.72978 1.36858 -0.28584 0.00705  -0.08019 2   PRO A CG  
19   C CD  . PRO A 2   ? 1.00271 0.71904 1.27999 -0.25659 -0.02111 -0.09303 2   PRO A CD  
27   N N   . PRO A 3   ? 0.67285 0.66663 1.16951 -0.29051 -0.09704 -0.08888 3   PRO A N   
28   C CA  . PRO A 3   ? 0.55639 0.62043 1.07241 -0.26295 -0.11063 -0.07110 3   PRO A CA  
29   C C   . PRO A 3   ? 0.60123 0.66020 1.09915 -0.23298 -0.06817 -0.03558 3   PRO A C   
30   O O   . PRO A 3   ? 0.46697 0.55045 0.93632 -0.20153 -0.07771 -0.02322 3   PRO A O   
31   C CB  . PRO A 3   ? 0.56586 0.70199 1.17179 -0.28449 -0.12239 -0.08063 3   PRO A CB  
32   C CG  . PRO A 3   ? 0.62147 0.73081 1.22436 -0.32030 -0.13435 -0.11003 3   PRO A CG  
33   C CD  . PRO A 3   ? 0.70784 0.72333 1.26045 -0.32745 -0.10110 -0.10779 3   PRO A CD  
41   N N   . SER A 4   ? 0.72247 0.74689 1.23222 -0.24232 -0.02208 -0.01879 4   SER A N   
42   C CA  . SER A 4   ? 0.67979 0.70006 1.16310 -0.21334 0.01516  0.01408  4   SER A CA  
43   C C   . SER A 4   ? 0.58414 0.57700 0.98160 -0.17733 0.00672  0.02111  4   SER A C   
44   O O   . SER A 4   ? 0.61052 0.62633 0.98916 -0.15004 0.01598  0.03863  4   SER A O   
45   C CB  . SER A 4   ? 0.77260 0.74189 1.25952 -0.22718 0.06342  0.03346  4   SER A CB  
46   O OG  . SER A 4   ? 0.80532 0.69697 1.24144 -0.23048 0.06550  0.02660  4   SER A OG  
52   N N   . ILE A 5   ? 0.64548 0.59122 0.99302 -0.17820 -0.00908 0.00487  5   ILE A N   
53   C CA  . ILE A 5   ? 0.54651 0.47145 0.82179 -0.14684 -0.01284 0.01004  5   ILE A CA  
54   C C   . ILE A 5   ? 0.47724 0.44375 0.73929 -0.13568 -0.04769 0.00129  5   ILE A C   
55   O O   . ILE A 5   ? 0.50748 0.48621 0.73868 -0.11021 -0.04503 0.01408  5   ILE A O   
56   C CB  . ILE A 5   ? 0.54878 0.40718 0.77747 -0.14922 -0.00935 -0.00435 5   ILE A CB  
57   C CG1 . ILE A 5   ? 0.61982 0.42582 0.85850 -0.15553 0.02757  0.01008  5   ILE A CG1 
58   C CG2 . ILE A 5   ? 0.57997 0.42774 0.74512 -0.11781 -0.01091 -0.00104 5   ILE A CG2 
59   C CD1 . ILE A 5   ? 0.81924 0.55195 1.01678 -0.15335 0.03529  -0.00396 5   ILE A CD1 
71   N N   . TRP A 6   ? 0.53004 0.51649 0.81352 -0.15484 -0.08207 -0.02025 6   TRP A N   
72   C CA  . TRP A 6   ? 0.53227 0.55099 0.79741 -0.14194 -0.11663 -0.02362 6   TRP A CA  
73   C C   . TRP A 6   ? 0.42457 0.49133 0.72569 -0.12317 -0.11148 -0.00415 6   TRP A C   
74   O O   . TRP A 6   ? 0.44542 0.51925 0.71371 -0.10228 -0.12323 0.00310  6   TRP A O   
75   C CB  . TRP A 6   ? 0.48203 0.52045 0.76905 -0.16438 -0.15870 -0.04808 6   TRP A CB  
76   C CG  . TRP A 6   ? 0.55812 0.54845 0.78094 -0.17601 -0.17488 -0.07284 6   TRP A CG  
77   C CD1 . TRP A 6   ? 0.58892 0.54749 0.81994 -0.20490 -0.17589 -0.09848 6   TRP A CD1 
78   C CD2 . TRP A 6   ? 0.56299 0.52879 0.70185 -0.16022 -0.18880 -0.07635 6   TRP A CD2 
79   N NE1 . TRP A 6   ? 0.64016 0.55602 0.79404 -0.20558 -0.19037 -0.12041 6   TRP A NE1 
80   C CE2 . TRP A 6   ? 0.62090 0.54250 0.71656 -0.17830 -0.19684 -0.10587 6   TRP A CE2 
81   C CE3 . TRP A 6   ? 0.57897 0.55227 0.67453 -0.13460 -0.19177 -0.05816 6   TRP A CE3 
82   C CZ2 . TRP A 6   ? 0.66308 0.55223 0.67072 -0.16951 -0.20546 -0.11699 6   TRP A CZ2 
83   C CZ3 . TRP A 6   ? 0.60075 0.54117 0.61331 -0.12880 -0.19960 -0.06628 6   TRP A CZ3 
84   C CH2 . TRP A 6   ? 0.68037 0.58131 0.64815 -0.14515 -0.20532 -0.09511 6   TRP A CH2 
95   N N   . SER A 7   ? 0.43511 0.53088 0.80193 -0.13101 -0.09019 0.00371  7   SER A N   
96   C CA  . SER A 7   ? 0.47118 0.61164 0.87330 -0.11232 -0.08114 0.01774  7   SER A CA  
97   C C   . SER A 7   ? 0.40251 0.52221 0.75225 -0.08704 -0.05595 0.03411  7   SER A C   
98   O O   . SER A 7   ? 0.36996 0.51609 0.72941 -0.06823 -0.05325 0.04094  7   SER A O   
99   C CB  . SER A 7   ? 0.41816 0.59512 0.90151 -0.12844 -0.05671 0.02094  7   SER A CB  
100  O OG  . SER A 7   ? 0.42222 0.57251 0.88719 -0.12570 -0.01130 0.03834  7   SER A OG  
106  N N   . ARG A 8   ? 0.48390 0.55809 0.78163 -0.08533 -0.03887 0.03835  8   ARG A N   
107  C CA  . ARG A 8   ? 0.41728 0.47930 0.66778 -0.06198 -0.02212 0.05060  8   ARG A CA  
108  C C   . ARG A 8   ? 0.42553 0.48437 0.63488 -0.04938 -0.04429 0.04509  8   ARG A C   
109  O O   . ARG A 8   ? 0.38545 0.44750 0.57045 -0.03270 -0.03549 0.05143  8   ARG A O   
110  C CB  . ARG A 8   ? 0.48426 0.50399 0.69935 -0.06005 -0.00013 0.05795  8   ARG A CB  
111  C CG  . ARG A 8   ? 0.45777 0.46477 0.70162 -0.07247 0.02800  0.06942  8   ARG A CG  
112  C CD  . ARG A 8   ? 0.52349 0.47448 0.73294 -0.07187 0.04094  0.07340  8   ARG A CD  
113  N NE  . ARG A 8   ? 0.51794 0.44285 0.74660 -0.08330 0.07173  0.08957  8   ARG A NE  
114  C CZ  . ARG A 8   ? 0.51523 0.43062 0.72159 -0.06650 0.09949  0.11545  8   ARG A CZ  
115  N NH1 . ARG A 8   ? 0.49266 0.42869 0.66142 -0.03843 0.09712  0.12394  8   ARG A NH1 
116  N NH2 . ARG A 8   ? 0.55968 0.44211 0.77889 -0.07962 0.13013  0.13313  8   ARG A NH2 
130  N N   . ILE A 9   ? 0.41924 0.46984 0.61675 -0.05879 -0.07187 0.03307  9   ILE A N   
131  C CA  . ILE A 9   ? 0.44000 0.48074 0.59191 -0.04951 -0.08885 0.03134  9   ILE A CA  
132  C C   . ILE A 9   ? 0.45079 0.51953 0.62857 -0.04029 -0.10658 0.03630  9   ILE A C   
133  O O   . ILE A 9   ? 0.45580 0.54801 0.67375 -0.04618 -0.12818 0.03229  9   ILE A O   
134  C CB  . ILE A 9   ? 0.43298 0.44709 0.54673 -0.06172 -0.10849 0.01755  9   ILE A CB  
135  C CG1 . ILE A 9   ? 0.44875 0.42920 0.54118 -0.06767 -0.08828 0.00990  9   ILE A CG1 
136  C CG2 . ILE A 9   ? 0.51876 0.51945 0.57880 -0.05312 -0.11939 0.02007  9   ILE A CG2 
137  C CD1 . ILE A 9   ? 0.44141 0.39488 0.50770 -0.08440 -0.10570 -0.01086 9   ILE A CD1 
149  N N   . VAL A 10  ? 0.40973 0.47645 0.56900 -0.02532 -0.09842 0.04359  10  VAL A N   
150  C CA  . VAL A 10  ? 0.48625 0.56715 0.66546 -0.01248 -0.11161 0.04867  10  VAL A CA  
151  C C   . VAL A 10  ? 0.45440 0.50515 0.58090 -0.00697 -0.11735 0.05331  10  VAL A C   
152  O O   . VAL A 10  ? 0.39295 0.42552 0.48142 -0.01092 -0.10156 0.05171  10  VAL A O   
153  C CB  . VAL A 10  ? 0.46007 0.56466 0.67798 -0.00083 -0.08870 0.05070  10  VAL A CB  
154  C CG1 . VAL A 10  ? 0.49590 0.62582 0.75952 -0.00975 -0.07306 0.04942  10  VAL A CG1 
155  C CG2 . VAL A 10  ? 0.47699 0.56588 0.65720 0.00492  -0.06710 0.05073  10  VAL A CG2 
165  N N   . ASN A 11  ? 0.44082 0.48681 0.56868 0.00274  -0.13914 0.06039  11  ASN A N   
166  C CA  . ASN A 11  ? 0.47544 0.48532 0.55450 0.00662  -0.14021 0.06885  11  ASN A CA  
167  C C   . ASN A 11  ? 0.49876 0.50418 0.58152 0.01046  -0.11311 0.06589  11  ASN A C   
168  O O   . ASN A 11  ? 0.45310 0.47953 0.57668 0.02016  -0.10290 0.06129  11  ASN A O   
169  C CB  . ASN A 11  ? 0.53283 0.53261 0.61417 0.02115  -0.16883 0.08149  11  ASN A CB  
170  C CG  . ASN A 11  ? 0.67267 0.69232 0.81300 0.04061  -0.16612 0.08224  11  ASN A CG  
171  O OD1 . ASN A 11  ? 0.71908 0.71217 0.85148 0.05089  -0.15521 0.08661  11  ASN A OD1 
172  N ND2 . ASN A 11  ? 0.68406 0.74954 0.88659 0.04456  -0.17313 0.07588  11  ASN A ND2 
179  N N   . PHE A 12  ? 0.50785 0.48865 0.54814 0.00144  -0.10055 0.06606  12  PHE A N   
180  C CA  . PHE A 12  ? 0.49161 0.47312 0.53549 0.00024  -0.07858 0.05836  12  PHE A CA  
181  C C   . PHE A 12  ? 0.46313 0.40926 0.46874 -0.00998 -0.07298 0.06345  12  PHE A C   
182  O O   . PHE A 12  ? 0.46852 0.40890 0.44281 -0.02221 -0.06615 0.06400  12  PHE A O   
183  C CB  . PHE A 12  ? 0.40834 0.41691 0.45724 -0.00432 -0.06259 0.04850  12  PHE A CB  
184  C CG  . PHE A 12  ? 0.46065 0.48276 0.51896 -0.00217 -0.04717 0.03795  12  PHE A CG  
185  C CD1 . PHE A 12  ? 0.45136 0.48515 0.53491 0.00906  -0.04318 0.03264  12  PHE A CD1 
186  C CD2 . PHE A 12  ? 0.43450 0.46200 0.47749 -0.01128 -0.03691 0.03071  12  PHE A CD2 
187  C CE1 . PHE A 12  ? 0.42613 0.47086 0.50831 0.01050  -0.03145 0.01907  12  PHE A CE1 
188  C CE2 . PHE A 12  ? 0.49324 0.53865 0.54450 -0.01053 -0.02891 0.01753  12  PHE A CE2 
189  C CZ  . PHE A 12  ? 0.45778 0.50897 0.52308 0.00004  -0.02730 0.01108  12  PHE A CZ  
199  N N   . GLY A 13  ? 0.49721 0.41662 0.50650 -0.00531 -0.07242 0.06689  13  GLY A N   
200  C CA  . GLY A 13  ? 0.46521 0.34290 0.43991 -0.01854 -0.06322 0.07442  13  GLY A CA  
201  C C   . GLY A 13  ? 0.51044 0.36012 0.43728 -0.02168 -0.07469 0.09371  13  GLY A C   
202  O O   . GLY A 13  ? 0.60833 0.45089 0.53024 -0.00698 -0.09944 0.10613  13  GLY A O   
206  N N   . SER A 14  ? 0.62353 0.46097 0.51441 -0.04068 -0.05675 0.09511  14  SER A N   
207  C CA  . SER A 14  ? 0.65987 0.46742 0.49065 -0.04580 -0.06122 0.11174  14  SER A CA  
208  C C   . SER A 14  ? 0.64175 0.47850 0.46039 -0.04534 -0.06888 0.10216  14  SER A C   
209  O O   . SER A 14  ? 0.62385 0.43952 0.38584 -0.05162 -0.06862 0.10910  14  SER A O   
210  C CB  . SER A 14  ? 0.72964 0.50954 0.52756 -0.06835 -0.03052 0.11690  14  SER A CB  
211  O OG  . SER A 14  ? 0.69765 0.52125 0.52517 -0.08137 -0.00766 0.09540  14  SER A OG  
217  N N   . GLY A 15  ? 0.56552 0.44445 0.43105 -0.03875 -0.07305 0.08607  15  GLY A N   
218  C CA  . GLY A 15  ? 0.57509 0.47345 0.43434 -0.03957 -0.07769 0.07531  15  GLY A CA  
219  C C   . GLY A 15  ? 0.53189 0.46178 0.44201 -0.02965 -0.09185 0.06749  15  GLY A C   
220  O O   . GLY A 15  ? 0.54437 0.47748 0.47789 -0.01969 -0.11253 0.07415  15  GLY A O   
224  N N   . TRP A 16  ? 0.44824 0.40130 0.37840 -0.03112 -0.07870 0.05485  16  TRP A N   
225  C CA  . TRP A 16  ? 0.43764 0.41382 0.40912 -0.02601 -0.08631 0.04967  16  TRP A CA  
226  C C   . TRP A 16  ? 0.42323 0.42068 0.41924 -0.02208 -0.06445 0.04381  16  TRP A C   
227  O O   . TRP A 16  ? 0.43191 0.43182 0.41510 -0.02311 -0.04818 0.04034  16  TRP A O   
228  C CB  . TRP A 16  ? 0.44209 0.40985 0.39743 -0.03312 -0.10019 0.04237  16  TRP A CB  
229  C CG  . TRP A 16  ? 0.46461 0.41478 0.38667 -0.03512 -0.12760 0.04795  16  TRP A CG  
230  C CD1 . TRP A 16  ? 0.54505 0.46495 0.40313 -0.03945 -0.12838 0.05240  16  TRP A CD1 
231  C CD2 . TRP A 16  ? 0.53382 0.49823 0.48355 -0.03091 -0.15901 0.05141  16  TRP A CD2 
232  N NE1 . TRP A 16  ? 0.57057 0.47990 0.40499 -0.03649 -0.16139 0.06062  16  TRP A NE1 
233  C CE2 . TRP A 16  ? 0.57483 0.51512 0.47013 -0.03029 -0.18317 0.05912  16  TRP A CE2 
234  C CE3 . TRP A 16  ? 0.51743 0.51622 0.53463 -0.02709 -0.16790 0.04916  16  TRP A CE3 
235  C CZ2 . TRP A 16  ? 0.53222 0.48501 0.44090 -0.02300 -0.22216 0.06448  16  TRP A CZ2 
236  C CZ3 . TRP A 16  ? 0.47612 0.49227 0.51676 -0.02220 -0.20246 0.05206  16  TRP A CZ3 
237  C CH2 . TRP A 16  ? 0.49879 0.49362 0.48663 -0.01875 -0.23236 0.05957  16  TRP A CH2 
248  N N   . GLY A 17  ? 0.41772 0.43341 0.45039 -0.01706 -0.06420 0.04381  17  GLY A N   
249  C CA  . GLY A 17  ? 0.35254 0.38357 0.39868 -0.01058 -0.04601 0.04273  17  GLY A CA  
250  C C   . GLY A 17  ? 0.40295 0.43574 0.47238 -0.01215 -0.04381 0.04454  17  GLY A C   
251  O O   . GLY A 17  ? 0.39610 0.42882 0.48418 -0.01987 -0.05759 0.04353  17  GLY A O   
255  N N   . PHE A 18  ? 0.36673 0.40165 0.43681 -0.00498 -0.02700 0.04806  18  PHE A N   
256  C CA  . PHE A 18  ? 0.41855 0.44148 0.50341 -0.00878 -0.01864 0.05212  18  PHE A CA  
257  C C   . PHE A 18  ? 0.39669 0.43196 0.49088 0.00223  -0.00049 0.06448  18  PHE A C   
258  O O   . PHE A 18  ? 0.35962 0.40167 0.43345 0.01688  0.00644  0.06843  18  PHE A O   
259  C CB  . PHE A 18  ? 0.42228 0.41629 0.48394 -0.00866 -0.01361 0.04689  18  PHE A CB  
260  C CG  . PHE A 18  ? 0.37932 0.34727 0.45450 -0.01564 -0.00412 0.04940  18  PHE A CG  
261  C CD1 . PHE A 18  ? 0.44417 0.40330 0.53954 -0.03642 -0.01570 0.04011  18  PHE A CD1 
262  C CD2 . PHE A 18  ? 0.42776 0.37848 0.49650 -0.00184 0.01508  0.06132  18  PHE A CD2 
263  C CE1 . PHE A 18  ? 0.47291 0.40436 0.58582 -0.04861 -0.00504 0.03979  18  PHE A CE1 
264  C CE2 . PHE A 18  ? 0.45128 0.36647 0.53110 -0.01018 0.02750  0.06584  18  PHE A CE2 
265  C CZ  . PHE A 18  ? 0.44046 0.34497 0.54446 -0.03625 0.01909  0.05364  18  PHE A CZ  
275  N N   . TRP A 19  ? 0.37722 0.41866 0.50176 -0.00498 0.00721  0.07031  19  TRP A N   
276  C CA  . TRP A 19  ? 0.37198 0.42029 0.49712 0.00392  0.02982  0.08456  19  TRP A CA  
277  C C   . TRP A 19  ? 0.46041 0.47489 0.57040 0.00592  0.04477  0.09724  19  TRP A C   
278  O O   . TRP A 19  ? 0.49519 0.48832 0.62795 -0.01043 0.05213  0.09923  19  TRP A O   
279  C CB  . TRP A 19  ? 0.36607 0.43588 0.53401 -0.00551 0.03906  0.08615  19  TRP A CB  
280  C CG  . TRP A 19  ? 0.35974 0.45884 0.54026 0.00167  0.03054  0.07680  19  TRP A CG  
281  C CD1 . TRP A 19  ? 0.35425 0.46716 0.56662 -0.00377 0.01065  0.06681  19  TRP A CD1 
282  C CD2 . TRP A 19  ? 0.37620 0.48922 0.53490 0.01745  0.04060  0.07571  19  TRP A CD2 
283  N NE1 . TRP A 19  ? 0.35052 0.47962 0.56539 0.00918  0.01062  0.06133  19  TRP A NE1 
284  C CE2 . TRP A 19  ? 0.29370 0.42264 0.47573 0.02025  0.02953  0.06380  19  TRP A CE2 
285  C CE3 . TRP A 19  ? 0.36810 0.48000 0.48642 0.03064  0.05558  0.08272  19  TRP A CE3 
286  C CZ2 . TRP A 19  ? 0.37501 0.51353 0.54324 0.03321  0.03645  0.05511  19  TRP A CZ2 
287  C CZ3 . TRP A 19  ? 0.43725 0.56541 0.53850 0.04210  0.05885  0.07271  19  TRP A CZ3 
288  C CH2 . TRP A 19  ? 0.44125 0.58005 0.56840 0.04204  0.05104  0.05728  19  TRP A CH2 
299  N N   . VAL A 20  ? 0.41522 0.42399 0.48984 0.02634  0.04807  0.10514  20  VAL A N   
300  C CA  . VAL A 20  ? 0.44588 0.41767 0.50328 0.03603  0.06271  0.12174  20  VAL A CA  
301  C C   . VAL A 20  ? 0.53331 0.49459 0.59000 0.03491  0.08777  0.14412  20  VAL A C   
302  O O   . VAL A 20  ? 0.52460 0.44454 0.58645 0.02697  0.10525  0.15748  20  VAL A O   
303  C CB  . VAL A 20  ? 0.43096 0.40960 0.45692 0.06344  0.05590  0.12542  20  VAL A CB  
304  C CG1 . VAL A 20  ? 0.47957 0.41526 0.48785 0.08053  0.06968  0.14583  20  VAL A CG1 
305  C CG2 . VAL A 20  ? 0.46581 0.45788 0.49654 0.06098  0.03857  0.10335  20  VAL A CG2 
315  N N   . SER A 21  ? 0.51823 0.51233 0.56578 0.04165  0.09319  0.14778  21  SER A N   
316  C CA  . SER A 21  ? 0.56362 0.55345 0.60468 0.04038  0.12212  0.16808  21  SER A CA  
317  C C   . SER A 21  ? 0.48019 0.51338 0.54305 0.03413  0.12462  0.15418  21  SER A C   
318  O O   . SER A 21  ? 0.43590 0.49401 0.51595 0.03232  0.10185  0.13199  21  SER A O   
319  C CB  . SER A 21  ? 0.55632 0.53341 0.53740 0.06815  0.13064  0.19192  21  SER A CB  
320  O OG  . SER A 21  ? 0.55036 0.56768 0.50379 0.08243  0.12152  0.18250  21  SER A OG  
326  N N   . PRO A 22  ? 0.45644 0.49618 0.51835 0.03188  0.15487  0.16715  22  PRO A N   
327  C CA  . PRO A 22  ? 0.45779 0.53861 0.53826 0.03224  0.16040  0.15130  22  PRO A CA  
328  C C   . PRO A 22  ? 0.50713 0.60714 0.54757 0.05189  0.14034  0.13520  22  PRO A C   
329  O O   . PRO A 22  ? 0.51184 0.63735 0.57590 0.05131  0.13357  0.11406  22  PRO A O   
330  C CB  . PRO A 22  ? 0.52936 0.60779 0.59854 0.03049  0.20392  0.17182  22  PRO A CB  
331  C CG  . PRO A 22  ? 0.52445 0.56252 0.60639 0.01437  0.22014  0.19460  22  PRO A CG  
332  C CD  . PRO A 22  ? 0.58516 0.59167 0.64004 0.02434  0.18984  0.19541  22  PRO A CD  
340  N N   . SER A 23  ? 0.54795 0.63650 0.53309 0.06934  0.12931  0.14347  23  SER A N   
341  C CA  . SER A 23  ? 0.54343 0.65457 0.49270 0.08437  0.11021  0.12598  23  SER A CA  
342  C C   . SER A 23  ? 0.55052 0.66583 0.50572 0.08600  0.07752  0.11298  23  SER A C   
343  O O   . SER A 23  ? 0.49522 0.63246 0.43895 0.09011  0.06031  0.09236  23  SER A O   
344  C CB  . SER A 23  ? 0.54994 0.65903 0.42906 0.10513  0.12008  0.14239  23  SER A CB  
345  O OG  . SER A 23  ? 0.79003 0.89887 0.65336 0.10403  0.15507  0.15088  23  SER A OG  
351  N N   . LEU A 24  ? 0.56201 0.65615 0.53583 0.08118  0.07141  0.12200  24  LEU A N   
352  C CA  . LEU A 24  ? 0.50001 0.59913 0.47798 0.08421  0.04753  0.11103  24  LEU A CA  
353  C C   . LEU A 24  ? 0.39672 0.48867 0.41466 0.06437  0.03908  0.09706  24  LEU A C   
354  O O   . LEU A 24  ? 0.46357 0.53538 0.50530 0.05149  0.04754  0.10297  24  LEU A O   
355  C CB  . LEU A 24  ? 0.55883 0.63699 0.51839 0.10046  0.04775  0.13038  24  LEU A CB  
356  C CG  . LEU A 24  ? 0.63538 0.73402 0.59636 0.11183  0.02619  0.11876  24  LEU A CG  
357  C CD1 . LEU A 24  ? 0.67092 0.81115 0.60775 0.12528  0.01116  0.10983  24  LEU A CD1 
358  C CD2 . LEU A 24  ? 0.63971 0.71156 0.59564 0.12955  0.02910  0.13611  24  LEU A CD2 
370  N N   . PHE A 25  ? 0.42324 0.53107 0.44622 0.06073  0.02193  0.07875  25  PHE A N   
371  C CA  . PHE A 25  ? 0.36497 0.46484 0.41207 0.04424  0.01226  0.06725  25  PHE A CA  
372  C C   . PHE A 25  ? 0.36133 0.46623 0.40164 0.04423  0.00125  0.05787  25  PHE A C   
373  O O   . PHE A 25  ? 0.37641 0.50479 0.41004 0.04813  -0.00467 0.04814  25  PHE A O   
374  C CB  . PHE A 25  ? 0.34161 0.45189 0.40253 0.03838  0.00988  0.05628  25  PHE A CB  
375  C CG  . PHE A 25  ? 0.34431 0.44303 0.42556 0.02571  -0.00216 0.05035  25  PHE A CG  
376  C CD1 . PHE A 25  ? 0.37622 0.46634 0.48168 0.01762  -0.00386 0.05589  25  PHE A CD1 
377  C CD2 . PHE A 25  ? 0.38486 0.48105 0.46019 0.02118  -0.01263 0.03970  25  PHE A CD2 
378  C CE1 . PHE A 25  ? 0.36345 0.44579 0.48108 0.00932  -0.02077 0.05159  25  PHE A CE1 
379  C CE2 . PHE A 25  ? 0.40485 0.48463 0.48814 0.01278  -0.02440 0.03937  25  PHE A CE2 
380  C CZ  . PHE A 25  ? 0.34796 0.42255 0.44979 0.00897  -0.03091 0.04563  25  PHE A CZ  
390  N N   . ILE A 26  ? 0.34833 0.43312 0.39157 0.03843  0.00023  0.05823  26  ILE A N   
391  C CA  . ILE A 26  ? 0.31694 0.40731 0.35522 0.03892  -0.00290 0.04947  26  ILE A CA  
392  C C   . ILE A 26  ? 0.38020 0.45723 0.41707 0.02100  -0.00885 0.04064  26  ILE A C   
393  O O   . ILE A 26  ? 0.37586 0.43313 0.41487 0.01157  -0.01413 0.04269  26  ILE A O   
394  C CB  . ILE A 26  ? 0.32163 0.39531 0.35530 0.05078  0.00480  0.05490  26  ILE A CB  
395  C CG1 . ILE A 26  ? 0.37099 0.40487 0.40405 0.03953  0.00807  0.05652  26  ILE A CG1 
396  C CG2 . ILE A 26  ? 0.37191 0.45476 0.40006 0.07338  0.00884  0.06923  26  ILE A CG2 
397  C CD1 . ILE A 26  ? 0.38917 0.39445 0.41562 0.05024  0.01803  0.05717  26  ILE A CD1 
409  N N   . THR A 27  ? 0.39354 0.48335 0.42725 0.01607  -0.00835 0.03173  27  THR A N   
410  C CA  . THR A 27  ? 0.40961 0.48112 0.43091 -0.00010 -0.01070 0.02782  27  THR A CA  
411  C C   . THR A 27  ? 0.36555 0.45151 0.38459 -0.00458 0.00029  0.01968  27  THR A C   
412  O O   . THR A 27  ? 0.37564 0.49099 0.41065 0.00688  0.00638  0.01547  27  THR A O   
413  C CB  . THR A 27  ? 0.38994 0.45681 0.41556 -0.00746 -0.01884 0.02850  27  THR A CB  
414  O OG1 . THR A 27  ? 0.34895 0.38845 0.35494 -0.01963 -0.02298 0.03124  27  THR A OG1 
415  C CG2 . THR A 27  ? 0.35517 0.44714 0.39249 -0.00853 -0.01573 0.01928  27  THR A CG2 
423  N N   . SER A 28  ? 0.35976 0.42640 0.35995 -0.02033 0.00352  0.01900  28  SER A N   
424  C CA  . SER A 28  ? 0.39290 0.47270 0.39266 -0.03005 0.02040  0.01208  28  SER A CA  
425  C C   . SER A 28  ? 0.37635 0.47325 0.39621 -0.04326 0.02162  0.00749  28  SER A C   
426  O O   . SER A 28  ? 0.34924 0.42407 0.36358 -0.04913 0.01175  0.01193  28  SER A O   
427  C CB  . SER A 28  ? 0.39902 0.44173 0.35630 -0.04189 0.02810  0.01582  28  SER A CB  
428  O OG  . SER A 28  ? 0.49913 0.54446 0.45169 -0.05914 0.04640  0.01467  28  SER A OG  
434  N N   . THR A 29  ? 0.35074 0.48826 0.39916 -0.04775 0.03386  -0.00374 29  THR A N   
435  C CA  . THR A 29  ? 0.39847 0.55298 0.47081 -0.06671 0.03604  -0.01324 29  THR A CA  
436  C C   . THR A 29  ? 0.38184 0.48756 0.42690 -0.08992 0.04653  -0.00466 29  THR A C   
437  O O   . THR A 29  ? 0.41026 0.49978 0.46186 -0.10315 0.04271  -0.00759 29  THR A O   
438  C CB  . THR A 29  ? 0.30312 0.51764 0.41934 -0.07057 0.04778  -0.02829 29  THR A CB  
439  O OG1 . THR A 29  ? 0.33760 0.59318 0.47419 -0.04298 0.03444  -0.03172 29  THR A OG1 
440  C CG2 . THR A 29  ? 0.35255 0.58842 0.50073 -0.09547 0.04799  -0.04322 29  THR A CG2 
448  N N   . HIS A 30  ? 0.41311 0.48922 0.42156 -0.09374 0.05994  0.00620  30  HIS A N   
449  C CA  . HIS A 30  ? 0.45671 0.48173 0.42778 -0.11342 0.07080  0.01983  30  HIS A CA  
450  C C   . HIS A 30  ? 0.53760 0.51481 0.48415 -0.10677 0.04834  0.03362  30  HIS A C   
451  O O   . HIS A 30  ? 0.54067 0.47267 0.46418 -0.12026 0.05361  0.04613  30  HIS A O   
452  C CB  . HIS A 30  ? 0.46708 0.47074 0.39080 -0.11535 0.08837  0.02816  30  HIS A CB  
453  C CG  . HIS A 30  ? 0.53385 0.55423 0.46580 -0.13690 0.12472  0.02360  30  HIS A CG  
454  N ND1 . HIS A 30  ? 0.51208 0.59707 0.49875 -0.13543 0.14052  0.00471  30  HIS A ND1 
455  C CD2 . HIS A 30  ? 0.56252 0.54534 0.45785 -0.16033 0.15048  0.03683  30  HIS A CD2 
456  C CE1 . HIS A 30  ? 0.55997 0.65334 0.55165 -0.15886 0.17616  0.00356  30  HIS A CE1 
457  N NE2 . HIS A 30  ? 0.56761 0.59596 0.50045 -0.17595 0.18510  0.02388  30  HIS A NE2 
465  N N   . VAL A 31  ? 0.47172 0.45702 0.42571 -0.08570 0.02572  0.03288  31  VAL A N   
466  C CA  . VAL A 31  ? 0.51255 0.46179 0.45145 -0.07590 0.00515  0.04533  31  VAL A CA  
467  C C   . VAL A 31  ? 0.50039 0.46057 0.47489 -0.06846 -0.00438 0.03642  31  VAL A C   
468  O O   . VAL A 31  ? 0.53037 0.45844 0.50069 -0.06170 -0.01550 0.04496  31  VAL A O   
469  C CB  . VAL A 31  ? 0.51261 0.45978 0.43400 -0.06077 -0.01180 0.05104  31  VAL A CB  
470  C CG1 . VAL A 31  ? 0.58588 0.52226 0.46605 -0.06729 -0.00098 0.05291  31  VAL A CG1 
471  C CG2 . VAL A 31  ? 0.40817 0.39365 0.36541 -0.04696 -0.01764 0.04032  31  VAL A CG2 
481  N N   . ILE A 32  ? 0.43392 0.43775 0.44021 -0.06686 -0.00092 0.01930  32  ILE A N   
482  C CA  . ILE A 32  ? 0.46621 0.47888 0.49434 -0.05823 -0.00913 0.00855  32  ILE A CA  
483  C C   . ILE A 32  ? 0.49199 0.46713 0.52070 -0.07157 -0.00472 0.00449  32  ILE A C   
484  O O   . ILE A 32  ? 0.48268 0.45347 0.51470 -0.09404 0.00850  -0.00177 32  ILE A O   
485  C CB  . ILE A 32  ? 0.42658 0.49205 0.47711 -0.05429 -0.00859 -0.00862 32  ILE A CB  
486  C CG1 . ILE A 32  ? 0.45145 0.52229 0.51088 -0.04576 -0.01519 -0.02166 32  ILE A CG1 
487  C CG2 . ILE A 32  ? 0.46685 0.55733 0.53353 -0.07394 0.00202  -0.02133 32  ILE A CG2 
488  C CD1 . ILE A 32  ? 0.40225 0.52286 0.47126 -0.03910 -0.01955 -0.03706 32  ILE A CD1 
500  N N   . PRO A 33  ? 0.49498 0.44088 0.52501 -0.05911 -0.01269 0.00707  33  PRO A N   
501  C CA  . PRO A 33  ? 0.54748 0.44632 0.57781 -0.06916 -0.00681 0.00243  33  PRO A CA  
502  C C   . PRO A 33  ? 0.48534 0.40487 0.53627 -0.08558 0.00062  -0.02733 33  PRO A C   
503  O O   . PRO A 33  ? 0.48994 0.44766 0.55271 -0.07506 -0.00515 -0.04552 33  PRO A O   
504  C CB  . PRO A 33  ? 0.55895 0.43510 0.59539 -0.04373 -0.01752 0.00807  33  PRO A CB  
505  C CG  . PRO A 33  ? 0.55283 0.45651 0.58791 -0.02723 -0.02992 0.02331  33  PRO A CG  
506  C CD  . PRO A 33  ? 0.48262 0.43404 0.51804 -0.03536 -0.02520 0.01541  33  PRO A CD  
514  N N   . GLN A 34  ? 0.50339 0.39633 0.55625 -0.11331 0.01364  -0.03242 34  GLN A N   
515  C CA  . GLN A 34  ? 0.55878 0.47609 0.63716 -0.13628 0.01843  -0.06449 34  GLN A CA  
516  C C   . GLN A 34  ? 0.57762 0.45054 0.66004 -0.13861 0.01886  -0.08583 34  GLN A C   
517  O O   . GLN A 34  ? 0.54395 0.44202 0.64428 -0.15409 0.01676  -0.11973 34  GLN A O   
518  C CB  . GLN A 34  ? 0.61437 0.53017 0.70356 -0.17122 0.03650  -0.06327 34  GLN A CB  
519  C CG  . GLN A 34  ? 0.60480 0.56752 0.69318 -0.16959 0.04126  -0.04908 34  GLN A CG  
520  C CD  . GLN A 34  ? 0.49592 0.53942 0.61053 -0.15788 0.02816  -0.06803 34  GLN A CD  
521  O OE1 . GLN A 34  ? 0.52156 0.58553 0.62318 -0.13000 0.01669  -0.05780 34  GLN A OE1 
522  N NE2 . GLN A 34  ? 0.42841 0.51753 0.58124 -0.17937 0.02866  -0.09530 34  GLN A NE2 
531  N N   . GLY A 35  ? 0.57627 0.38471 0.64316 -0.12238 0.02012  -0.06917 35  GLY A N   
532  C CA  . GLY A 35  ? 0.67177 0.42934 0.74280 -0.11926 0.02362  -0.08960 35  GLY A CA  
533  C C   . GLY A 35  ? 0.63053 0.39936 0.70213 -0.08330 0.01533  -0.09722 35  GLY A C   
534  O O   . GLY A 35  ? 0.70185 0.42334 0.77613 -0.07375 0.02089  -0.11306 35  GLY A O   
538  N N   . ALA A 36  ? 0.59631 0.42412 0.66721 -0.06392 0.00585  -0.08718 36  ALA A N   
539  C CA  . ALA A 36  ? 0.57323 0.41487 0.64866 -0.03180 0.00348  -0.08958 36  ALA A CA  
540  C C   . ALA A 36  ? 0.60550 0.47415 0.67698 -0.03114 0.00731  -0.12717 36  ALA A C   
541  O O   . ALA A 36  ? 0.63720 0.54885 0.70201 -0.04786 0.00221  -0.14374 36  ALA A O   
542  C CB  . ALA A 36  ? 0.50638 0.39567 0.58302 -0.01646 -0.00497 -0.06468 36  ALA A CB  
548  N N   . LYS A 37  ? 0.68922 0.53421 0.76361 -0.00933 0.01580  -0.14125 37  LYS A N   
549  C CA  . LYS A 37  ? 0.74219 0.61043 0.80151 -0.00296 0.02223  -0.17647 37  LYS A CA  
550  C C   . LYS A 37  ? 0.62865 0.55432 0.68129 0.01875  0.02430  -0.16489 37  LYS A C   
551  O O   . LYS A 37  ? 0.62742 0.57906 0.65505 0.02417  0.02995  -0.18886 37  LYS A O   
552  C CB  . LYS A 37  ? 0.77390 0.58502 0.83750 0.01181  0.03696  -0.20051 37  LYS A CB  
553  C CG  . LYS A 37  ? 0.95504 0.69327 1.02335 -0.00982 0.03923  -0.21306 37  LYS A CG  
554  C CD  . LYS A 37  ? 1.04603 0.78288 1.09648 -0.03890 0.03883  -0.26072 37  LYS A CD  
555  C CE  . LYS A 37  ? 0.93409 0.64398 0.99543 -0.07969 0.03416  -0.26014 37  LYS A CE  
556  N NZ  . LYS A 37  ? 0.83738 0.60873 0.90478 -0.09276 0.02189  -0.23101 37  LYS A NZ  
570  N N   . GLU A 38  ? 0.60803 0.55054 0.67860 0.02972  0.02059  -0.12938 38  GLU A N   
571  C CA  . GLU A 38  ? 0.51625 0.50488 0.58734 0.04696  0.02660  -0.11609 38  GLU A CA  
572  C C   . GLU A 38  ? 0.48366 0.48562 0.57449 0.04677  0.01613  -0.08058 38  GLU A C   
573  O O   . GLU A 38  ? 0.49339 0.46532 0.59691 0.04190  0.00615  -0.06583 38  GLU A O   
574  C CB  . GLU A 38  ? 0.53475 0.51857 0.62054 0.07233  0.04639  -0.12630 38  GLU A CB  
575  C CG  . GLU A 38  ? 0.66347 0.60677 0.78813 0.08753  0.04691  -0.11860 38  GLU A CG  
576  C CD  . GLU A 38  ? 0.71916 0.68080 0.87891 0.09541  0.03503  -0.08309 38  GLU A CD  
577  O OE1 . GLU A 38  ? 0.58910 0.59656 0.75375 0.09491  0.03697  -0.06952 38  GLU A OE1 
578  O OE2 . GLU A 38  ? 0.79972 0.72665 0.97929 0.10172  0.02270  -0.06883 38  GLU A OE2 
585  N N   . PHE A 39  ? 0.43874 0.48121 0.52608 0.05154  0.01903  -0.06734 39  PHE A N   
586  C CA  . PHE A 39  ? 0.47128 0.52676 0.57890 0.05218  0.01171  -0.03916 39  PHE A CA  
587  C C   . PHE A 39  ? 0.48136 0.56509 0.60823 0.06668  0.02757  -0.03246 39  PHE A C   
588  O O   . PHE A 39  ? 0.46824 0.57230 0.57154 0.07038  0.04240  -0.03860 39  PHE A O   
589  C CB  . PHE A 39  ? 0.49547 0.56677 0.58320 0.03820  0.00199  -0.02845 39  PHE A CB  
590  C CG  . PHE A 39  ? 0.44738 0.49967 0.52389 0.02093  -0.00840 -0.03404 39  PHE A CG  
591  C CD1 . PHE A 39  ? 0.43733 0.45379 0.52213 0.01515  -0.01519 -0.02509 39  PHE A CD1 
592  C CD2 . PHE A 39  ? 0.43638 0.50939 0.49509 0.01061  -0.01098 -0.04654 39  PHE A CD2 
593  C CE1 . PHE A 39  ? 0.47798 0.47468 0.55119 -0.00402 -0.01797 -0.02786 39  PHE A CE1 
594  C CE2 . PHE A 39  ? 0.47772 0.54080 0.53670 -0.00878 -0.01621 -0.05285 39  PHE A CE2 
595  C CZ  . PHE A 39  ? 0.42042 0.44296 0.48554 -0.01784 -0.01652 -0.04304 39  PHE A CZ  
605  N N   . PHE A 40  ? 0.48622 0.57305 0.65572 0.07447  0.02457  -0.01951 40  PHE A N   
606  C CA  . PHE A 40  ? 0.47595 0.59583 0.67905 0.08369  0.04180  -0.01291 40  PHE A CA  
607  C C   . PHE A 40  ? 0.48504 0.61309 0.68381 0.09837  0.07017  -0.03206 40  PHE A C   
608  O O   . PHE A 40  ? 0.47341 0.62835 0.67210 0.10109  0.09417  -0.02847 40  PHE A O   
609  C CB  . PHE A 40  ? 0.39884 0.53828 0.58846 0.07166  0.04527  0.00311  40  PHE A CB  
610  C CG  . PHE A 40  ? 0.41445 0.54156 0.59698 0.05764  0.02110  0.01589  40  PHE A CG  
611  C CD1 . PHE A 40  ? 0.39953 0.52252 0.61446 0.05573  0.00160  0.02386  40  PHE A CD1 
612  C CD2 . PHE A 40  ? 0.37825 0.49977 0.52036 0.04882  0.01735  0.01877  40  PHE A CD2 
613  C CE1 . PHE A 40  ? 0.39611 0.50487 0.59416 0.04305  -0.01817 0.03281  40  PHE A CE1 
614  C CE2 . PHE A 40  ? 0.34161 0.45138 0.47679 0.03775  0.00039  0.02747  40  PHE A CE2 
615  C CZ  . PHE A 40  ? 0.41698 0.51794 0.57552 0.03374  -0.01586 0.03364  40  PHE A CZ  
625  N N   . GLY A 41  ? 0.48759 0.58722 0.67860 0.10714  0.07057  -0.05305 41  GLY A N   
626  C CA  . GLY A 41  ? 0.52637 0.62667 0.70902 0.12257  0.09817  -0.07749 41  GLY A CA  
627  C C   . GLY A 41  ? 0.58714 0.68663 0.70280 0.11578  0.10746  -0.09586 41  GLY A C   
628  O O   . GLY A 41  ? 0.58072 0.67641 0.67594 0.12774  0.13025  -0.12103 41  GLY A O   
632  N N   . VAL A 42  ? 0.52098 0.62574 0.60113 0.09919  0.08966  -0.08589 42  VAL A N   
633  C CA  . VAL A 42  ? 0.54376 0.65686 0.56163 0.09512  0.09078  -0.10048 42  VAL A CA  
634  C C   . VAL A 42  ? 0.54991 0.63818 0.55040 0.08193  0.06975  -0.12567 42  VAL A C   
635  O O   . VAL A 42  ? 0.51159 0.59009 0.53034 0.06772  0.04915  -0.11461 42  VAL A O   
636  C CB  . VAL A 42  ? 0.58891 0.72645 0.58490 0.08905  0.08355  -0.07367 42  VAL A CB  
637  C CG1 . VAL A 42  ? 0.53007 0.68040 0.45965 0.09092  0.08048  -0.08656 42  VAL A CG1 
638  C CG2 . VAL A 42  ? 0.51720 0.67174 0.53847 0.09545  0.10605  -0.04773 42  VAL A CG2 
648  N N   . PRO A 43  ? 0.55293 0.62978 0.51838 0.08372  0.07612  -0.16093 43  PRO A N   
649  C CA  . PRO A 43  ? 0.57827 0.63369 0.53212 0.06466  0.05597  -0.18795 43  PRO A CA  
650  C C   . PRO A 43  ? 0.53009 0.61552 0.47231 0.04797  0.03084  -0.17619 43  PRO A C   
651  O O   . PRO A 43  ? 0.60137 0.72306 0.51245 0.05474  0.02758  -0.16441 43  PRO A O   
652  C CB  . PRO A 43  ? 0.65762 0.70612 0.56446 0.06982  0.06714  -0.23007 43  PRO A CB  
653  C CG  . PRO A 43  ? 0.64950 0.69631 0.56218 0.09503  0.10034  -0.22680 43  PRO A CG  
654  C CD  . PRO A 43  ? 0.61847 0.69789 0.55617 0.10140  0.10485  -0.18145 43  PRO A CD  
662  N N   . ILE A 44  ? 0.57544 0.65332 0.42188 0.11387  0.10486  0.04833  44  ILE A N   
663  C CA  . ILE A 44  ? 0.57700 0.64248 0.44675 0.09353  0.10127  0.04404  44  ILE A CA  
664  C C   . ILE A 44  ? 0.57735 0.65495 0.48800 0.05389  0.09292  0.03104  44  ILE A C   
665  O O   . ILE A 44  ? 0.53362 0.62882 0.47152 0.03909  0.07340  0.02614  44  ILE A O   
666  C CB  . ILE A 44  ? 0.71231 0.70274 0.53835 0.11524  0.14258  0.04691  44  ILE A CB  
667  C CG1 . ILE A 44  ? 0.69851 0.67739 0.55669 0.09018  0.14458  0.03732  44  ILE A CG1 
668  C CG2 . ILE A 44  ? 0.78325 0.71048 0.57956 0.11340  0.19172  0.04248  44  ILE A CG2 
669  C CD1 . ILE A 44  ? 0.70956 0.72959 0.58232 0.09728  0.10741  0.04320  44  ILE A CD1 
681  N N   . LYS A 45  ? 0.56343 0.63466 0.47385 0.04318  0.10536  0.02204  45  LYS A N   
682  C CA  . LYS A 45  ? 0.58510 0.67946 0.52822 0.01879  0.09134  0.00038  45  LYS A CA  
683  C C   . LYS A 45  ? 0.57120 0.70104 0.51679 0.01846  0.05501  0.01027  45  LYS A C   
684  O O   . LYS A 45  ? 0.48636 0.63257 0.44371 0.01459  0.03574  -0.00365 45  LYS A O   
685  C CB  . LYS A 45  ? 0.67781 0.76188 0.61782 0.01076  0.11217  -0.01726 45  LYS A CB  
686  C CG  . LYS A 45  ? 0.78614 0.89931 0.76646 -0.00889 0.10552  -0.06021 45  LYS A CG  
687  C CD  . LYS A 45  ? 0.79638 0.89920 0.81530 -0.02609 0.13079  -0.09166 45  LYS A CD  
688  C CE  . LYS A 45  ? 0.94549 1.09071 1.02014 -0.04815 0.13563  -0.15519 45  LYS A CE  
689  N NZ  . LYS A 45  ? 0.94505 1.16143 1.02913 -0.03162 0.07831  -0.17208 45  LYS A NZ  
703  N N   . GLN A 46  ? 0.53919 0.67834 0.47042 0.02597  0.05060  0.02920  46  GLN A N   
704  C CA  . GLN A 46  ? 0.50757 0.65821 0.43487 0.02082  0.03554  0.03695  46  GLN A CA  
705  C C   . GLN A 46  ? 0.47521 0.62858 0.41427 0.01715  0.02606  0.04054  46  GLN A C   
706  O O   . GLN A 46  ? 0.50307 0.64610 0.43039 0.01207  0.02365  0.04590  46  GLN A O   
707  C CB  . GLN A 46  ? 0.53096 0.69456 0.45268 0.02117  0.04574  0.04344  46  GLN A CB  
708  C CG  . GLN A 46  ? 0.56438 0.72282 0.47077 0.02725  0.05718  0.04243  46  GLN A CG  
709  C CD  . GLN A 46  ? 0.65583 0.83193 0.56097 0.02700  0.06769  0.04522  46  GLN A CD  
710  O OE1 . GLN A 46  ? 0.64691 0.82559 0.55714 0.01429  0.07275  0.04529  46  GLN A OE1 
711  N NE2 . GLN A 46  ? 0.65471 0.83715 0.55151 0.04089  0.07839  0.04456  46  GLN A NE2 
720  N N   . ILE A 47  ? 0.48509 0.63999 0.43712 0.02222  0.02688  0.03837  47  ILE A N   
721  C CA  . ILE A 47  ? 0.46574 0.62416 0.42924 0.01943  0.01773  0.03974  47  ILE A CA  
722  C C   . ILE A 47  ? 0.50075 0.64463 0.46904 0.01687  0.00918  0.03466  47  ILE A C   
723  O O   . ILE A 47  ? 0.48322 0.62101 0.46113 0.01740  0.01699  0.02224  47  ILE A O   
724  C CB  . ILE A 47  ? 0.48237 0.65113 0.44768 0.03631  0.02103  0.03781  47  ILE A CB  
725  C CG1 . ILE A 47  ? 0.52166 0.72630 0.48752 0.04889  0.02297  0.03137  47  ILE A CG1 
726  C CG2 . ILE A 47  ? 0.46042 0.63543 0.43895 0.03276  0.01038  0.03533  47  ILE A CG2 
727  C CD1 . ILE A 47  ? 0.53635 0.74990 0.48095 0.08826  0.02401  0.02688  47  ILE A CD1 
739  N N   . GLN A 48  ? 0.51786 0.65514 0.48042 0.01439  -0.00132 0.03891  48  GLN A N   
740  C CA  . GLN A 48  ? 0.53710 0.67044 0.50325 0.02055  -0.01416 0.03065  48  GLN A CA  
741  C C   . GLN A 48  ? 0.49518 0.62565 0.47979 0.01711  -0.01265 0.03186  48  GLN A C   
742  O O   . GLN A 48  ? 0.47075 0.59363 0.44984 0.01355  -0.01384 0.04082  48  GLN A O   
743  C CB  . GLN A 48  ? 0.61008 0.72208 0.53788 0.03318  -0.02244 0.03821  48  GLN A CB  
744  C CG  . GLN A 48  ? 0.84428 0.95415 0.73968 0.05038  -0.02767 0.03342  48  GLN A CG  
745  C CD  . GLN A 48  ? 1.16738 1.23891 0.99852 0.08178  -0.03323 0.04200  48  GLN A CD  
746  O OE1 . GLN A 48  ? 1.19839 1.21675 0.98886 0.07878  -0.00967 0.06346  48  GLN A OE1 
747  N NE2 . GLN A 48  ? 1.33284 1.42929 1.15111 0.11596  -0.05991 0.01962  48  GLN A NE2 
756  N N   . VAL A 49  ? 0.41214 0.54214 0.41675 0.01684  -0.00305 0.01950  49  VAL A N   
757  C CA  . VAL A 49  ? 0.41453 0.52975 0.42563 0.01891  0.00467  0.02170  49  VAL A CA  
758  C C   . VAL A 49  ? 0.45045 0.57104 0.48302 0.01681  -0.00403 0.00749  49  VAL A C   
759  O O   . VAL A 49  ? 0.37423 0.51350 0.43308 0.01340  -0.00206 -0.01935 49  VAL A O   
760  C CB  . VAL A 49  ? 0.41879 0.50618 0.42137 0.02546  0.03539  0.01881  49  VAL A CB  
761  C CG1 . VAL A 49  ? 0.47641 0.53563 0.46569 0.03791  0.04602  0.02519  49  VAL A CG1 
762  C CG2 . VAL A 49  ? 0.45858 0.54690 0.43440 0.03815  0.04078  0.02944  49  VAL A CG2 
772  N N   A HIS A 50  ? 0.42845 0.54088 0.45487 0.01974  -0.01380 0.01827  50  HIS A N   
773  N N   B HIS A 50  ? 0.43615 0.54847 0.46275 0.01972  -0.01361 0.01819  50  HIS A N   
774  C CA  A HIS A 50  ? 0.43817 0.55465 0.48155 0.02295  -0.02172 0.00651  50  HIS A CA  
775  C CA  B HIS A 50  ? 0.43835 0.55509 0.48215 0.02290  -0.02159 0.00613  50  HIS A CA  
776  C C   A HIS A 50  ? 0.43906 0.53186 0.48879 0.02103  -0.00476 0.00936  50  HIS A C   
777  C C   B HIS A 50  ? 0.44129 0.53430 0.49073 0.02116  -0.00551 0.00967  50  HIS A C   
778  O O   A HIS A 50  ? 0.44746 0.52242 0.47469 0.02620  0.00242  0.02464  50  HIS A O   
779  O O   B HIS A 50  ? 0.44952 0.52550 0.47654 0.02608  0.00021  0.02539  50  HIS A O   
780  C CB  A HIS A 50  ? 0.46671 0.57596 0.48248 0.03357  -0.04089 0.01914  50  HIS A CB  
781  C CB  B HIS A 50  ? 0.44810 0.55891 0.46434 0.03415  -0.04143 0.01797  50  HIS A CB  
782  C CG  A HIS A 50  ? 0.47481 0.59109 0.50020 0.04690  -0.05250 0.00667  50  HIS A CG  
783  C CG  B HIS A 50  ? 0.45196 0.56916 0.44117 0.04892  -0.05306 0.01600  50  HIS A CG  
784  N ND1 A HIS A 50  ? 0.44861 0.60620 0.50018 0.06106  -0.06529 -0.02635 50  HIS A ND1 
785  N ND1 B HIS A 50  ? 0.52987 0.63783 0.49838 0.04271  -0.04512 0.02786  50  HIS A ND1 
786  C CD2 A HIS A 50  ? 0.48638 0.58180 0.50272 0.05047  -0.05406 0.01651  50  HIS A CD2 
787  C CD2 B HIS A 50  ? 0.48945 0.62133 0.46136 0.07776  -0.07244 0.00115  50  HIS A CD2 
788  C CE1 A HIS A 50  ? 0.41529 0.58081 0.47376 0.07601  -0.07580 -0.03616 50  HIS A CE1 
789  C CE1 B HIS A 50  ? 0.55309 0.65849 0.48713 0.06473  -0.05525 0.02491  50  HIS A CE1 
790  N NE2 A HIS A 50  ? 0.43159 0.55248 0.46464 0.06923  -0.06773 -0.00610 50  HIS A NE2 
791  N NE2 B HIS A 50  ? 0.44626 0.56748 0.37727 0.09106  -0.07439 0.00807  50  HIS A NE2 
806  N N   . LYS A 51  ? 0.42465 0.52158 0.50363 0.01879  0.00154  -0.01055 51  LYS A N   
807  C CA  . LYS A 51  ? 0.41646 0.47865 0.49545 0.01844  0.02605  -0.00875 51  LYS A CA  
808  C C   . LYS A 51  ? 0.40137 0.47817 0.50781 0.01878  0.01674  -0.02336 51  LYS A C   
809  O O   . LYS A 51  ? 0.34676 0.46504 0.49583 0.01589  0.01152  -0.05725 51  LYS A O   
810  C CB  . LYS A 51  ? 0.37954 0.41002 0.46669 0.01037  0.07248  -0.02529 51  LYS A CB  
811  C CG  . LYS A 51  ? 0.61078 0.57392 0.65030 0.02676  0.10555  -0.00587 51  LYS A CG  
812  C CD  . LYS A 51  ? 0.77625 0.68125 0.79067 0.02862  0.16069  -0.01183 51  LYS A CD  
813  C CE  . LYS A 51  ? 0.67187 0.59071 0.66180 0.03753  0.14831  -0.00018 51  LYS A CE  
814  N NZ  . LYS A 51  ? 0.67279 0.62554 0.63469 0.05921  0.10176  0.02461  51  LYS A NZ  
828  N N   . SER A 52  ? 0.40711 0.45809 0.49110 0.02589  0.01266  -0.00377 52  SER A N   
829  C CA  . SER A 52  ? 0.45560 0.51143 0.55787 0.02932  0.00652  -0.01292 52  SER A CA  
830  C C   . SER A 52  ? 0.37078 0.37761 0.45797 0.03055  0.03545  -0.00415 52  SER A C   
831  O O   . SER A 52  ? 0.37630 0.36154 0.42886 0.04049  0.02507  0.01757  52  SER A O   
832  C CB  . SER A 52  ? 0.40576 0.46487 0.47986 0.04098  -0.02448 0.00512  52  SER A CB  
833  O OG  . SER A 52  ? 0.50064 0.56834 0.58841 0.05189  -0.03261 -0.00620 52  SER A OG  
839  N N   . GLY A 53  ? 0.39401 0.37866 0.50412 0.02130  0.07759  -0.02563 53  GLY A N   
840  C CA  . GLY A 53  ? 0.44016 0.35480 0.51447 0.03053  0.11773  -0.01448 53  GLY A CA  
841  C C   . GLY A 53  ? 0.51569 0.38875 0.51915 0.05573  0.12180  0.01418  53  GLY A C   
842  O O   . GLY A 53  ? 0.54244 0.39550 0.52913 0.05801  0.14565  0.01290  53  GLY A O   
846  N N   . GLU A 54  ? 0.48016 0.34673 0.44283 0.07828  0.09751  0.03413  54  GLU A N   
847  C CA  . GLU A 54  ? 0.52368 0.37353 0.42292 0.11348  0.09165  0.04921  54  GLU A CA  
848  C C   . GLU A 54  ? 0.46104 0.37945 0.37589 0.10806  0.04535  0.04879  54  GLU A C   
849  O O   . GLU A 54  ? 0.48091 0.41166 0.35945 0.13686  0.03412  0.04925  54  GLU A O   
850  C CB  . GLU A 54  ? 0.55597 0.36401 0.40126 0.14804  0.09655  0.05773  54  GLU A CB  
851  C CG  . GLU A 54  ? 0.67253 0.38385 0.47156 0.16605  0.15908  0.06223  54  GLU A CG  
852  C CD  . GLU A 54  ? 0.78706 0.43576 0.52045 0.19682  0.20109  0.06977  54  GLU A CD  
853  O OE1 . GLU A 54  ? 0.75471 0.42109 0.43539 0.23922  0.17464  0.07745  54  GLU A OE1 
854  O OE2 . GLU A 54  ? 0.86543 0.44920 0.60223 0.17884  0.26395  0.06250  54  GLU A OE2 
861  N N   . PHE A 55  ? 0.41188 0.37214 0.37490 0.07680  0.02276  0.04404  55  PHE A N   
862  C CA  . PHE A 55  ? 0.42856 0.43478 0.40359 0.06547  -0.00444 0.04237  55  PHE A CA  
863  C C   . PHE A 55  ? 0.42743 0.44766 0.41238 0.05771  0.00052  0.04128  55  PHE A C   
864  O O   . PHE A 55  ? 0.43463 0.45866 0.44469 0.04322  0.00417  0.03609  55  PHE A O   
865  C CB  . PHE A 55  ? 0.45438 0.47006 0.44970 0.04545  -0.01927 0.04269  55  PHE A CB  
866  C CG  . PHE A 55  ? 0.45709 0.49572 0.45446 0.03152  -0.02992 0.03838  55  PHE A CG  
867  C CD1 . PHE A 55  ? 0.47480 0.52720 0.47656 0.02112  -0.02973 0.03925  55  PHE A CD1 
868  C CD2 . PHE A 55  ? 0.43782 0.48117 0.43508 0.02579  -0.03320 0.02786  55  PHE A CD2 
869  C CE1 . PHE A 55  ? 0.45384 0.51586 0.45814 0.00355  -0.02568 0.03143  55  PHE A CE1 
870  C CE2 . PHE A 55  ? 0.44337 0.50408 0.45270 0.00373  -0.02867 0.01301  55  PHE A CE2 
871  C CZ  . PHE A 55  ? 0.42532 0.49101 0.43732 -0.00831 -0.02138 0.01567  55  PHE A CZ  
881  N N   . CYS A 56  ? 0.41503 0.45084 0.38140 0.07167  -0.00178 0.04052  56  CYS A N   
882  C CA  . CYS A 56  ? 0.39230 0.43959 0.36275 0.06656  0.00363  0.04043  56  CYS A CA  
883  C C   . CYS A 56  ? 0.39350 0.48484 0.38015 0.05214  -0.01604 0.03544  56  CYS A C   
884  O O   . CYS A 56  ? 0.37767 0.49975 0.36395 0.06048  -0.02636 0.02349  56  CYS A O   
885  C CB  . CYS A 56  ? 0.41737 0.43750 0.34453 0.09953  0.02472  0.04354  56  CYS A CB  
886  S SG  . CYS A 56  ? 0.49076 0.50736 0.41809 0.09275  0.04234  0.04373  56  CYS A SG  
892  N N   . ARG A 57  ? 0.41102 0.50652 0.41163 0.03274  -0.01772 0.03813  57  ARG A N   
893  C CA  . ARG A 57  ? 0.39629 0.51055 0.40243 0.01694  -0.02205 0.03549  57  ARG A CA  
894  C C   . ARG A 57  ? 0.40892 0.53486 0.41257 0.01718  -0.01772 0.03645  57  ARG A C   
895  O O   . ARG A 57  ? 0.41099 0.52566 0.41245 0.01957  -0.01497 0.03936  57  ARG A O   
896  C CB  . ARG A 57  ? 0.52552 0.61369 0.52356 0.00607  -0.02235 0.04245  57  ARG A CB  
897  C CG  . ARG A 57  ? 0.61846 0.69675 0.60888 -0.01179 -0.00861 0.03942  57  ARG A CG  
898  C CD  . ARG A 57  ? 0.89088 0.91710 0.84761 -0.01027 0.00036  0.05086  57  ARG A CD  
899  N NE  . ARG A 57  ? 0.83862 0.85383 0.77174 0.01495  -0.01408 0.06061  57  ARG A NE  
900  C CZ  . ARG A 57  ? 0.90267 0.90292 0.80258 0.02879  -0.01240 0.06612  57  ARG A CZ  
901  N NH1 . ARG A 57  ? 1.04537 1.02642 0.92790 0.01587  0.00976  0.06951  57  ARG A NH1 
902  N NH2 . ARG A 57  ? 0.83061 0.84064 0.71640 0.05858  -0.03274 0.06194  57  ARG A NH2 
916  N N   . LEU A 58  ? 0.38146 0.53724 0.39235 0.01344  -0.01590 0.02666  58  LEU A N   
917  C CA  . LEU A 58  ? 0.39438 0.56297 0.40234 0.01446  -0.01065 0.02711  58  LEU A CA  
918  C C   . LEU A 58  ? 0.39219 0.56186 0.40605 -0.00889 0.00042  0.02259  58  LEU A C   
919  O O   . LEU A 58  ? 0.35453 0.55307 0.39309 -0.02276 0.00852  0.00120  58  LEU A O   
920  C CB  . LEU A 58  ? 0.36581 0.56814 0.37127 0.03978  -0.01280 0.01585  58  LEU A CB  
921  C CG  . LEU A 58  ? 0.42118 0.59186 0.39376 0.07155  -0.00653 0.02548  58  LEU A CG  
922  C CD1 . LEU A 58  ? 0.41841 0.57623 0.38353 0.08360  -0.01139 0.02393  58  LEU A CD1 
923  C CD2 . LEU A 58  ? 0.47280 0.65934 0.41710 0.10927  -0.00288 0.02027  58  LEU A CD2 
935  N N   . ARG A 59  ? 0.40599 0.54320 0.39580 -0.01125 0.00533  0.03664  59  ARG A N   
936  C CA  . ARG A 59  ? 0.48985 0.60258 0.46230 -0.02556 0.02676  0.03813  59  ARG A CA  
937  C C   . ARG A 59  ? 0.49054 0.62757 0.46862 -0.02531 0.03187  0.03433  59  ARG A C   
938  O O   . ARG A 59  ? 0.45685 0.59518 0.42292 -0.01032 0.02027  0.04233  59  ARG A O   
939  C CB  . ARG A 59  ? 0.54488 0.60149 0.46611 -0.01127 0.02760  0.05588  59  ARG A CB  
940  C CG  . ARG A 59  ? 0.76345 0.76785 0.63696 -0.01260 0.05764  0.06429  59  ARG A CG  
941  C CD  . ARG A 59  ? 0.80365 0.77467 0.68059 -0.04199 0.09984  0.05482  59  ARG A CD  
942  N NE  . ARG A 59  ? 1.06753 0.98421 0.90990 -0.03505 0.10870  0.06389  59  ARG A NE  
943  C CZ  . ARG A 59  ? 1.06931 0.95211 0.91839 -0.06329 0.14774  0.05110  59  ARG A CZ  
944  N NH1 . ARG A 59  ? 0.92773 0.83892 0.82974 -0.10373 0.18072  0.01958  59  ARG A NH1 
945  N NH2 . ARG A 59  ? 0.94926 0.77350 0.75600 -0.05107 0.15605  0.06338  59  ARG A NH2 
959  N N   . PHE A 60  ? 0.55473 0.51656 0.41927 0.07420  0.05870  -0.00149 60  PHE A N   
960  C CA  . PHE A 60  ? 0.59174 0.56239 0.44191 0.08492  0.07408  -0.01660 60  PHE A CA  
961  C C   . PHE A 60  ? 0.58705 0.56350 0.40072 0.06776  0.08521  -0.01692 60  PHE A C   
962  O O   . PHE A 60  ? 0.60872 0.58936 0.41366 0.04743  0.08186  -0.00007 60  PHE A O   
963  C CB  . PHE A 60  ? 0.52810 0.53487 0.41499 0.09960  0.08360  -0.02320 60  PHE A CB  
964  C CG  . PHE A 60  ? 0.49452 0.48587 0.39836 0.11584  0.06957  -0.02263 60  PHE A CG  
965  C CD1 . PHE A 60  ? 0.47128 0.45791 0.38429 0.10549  0.05832  -0.01093 60  PHE A CD1 
966  C CD2 . PHE A 60  ? 0.51379 0.48801 0.41781 0.13953  0.06708  -0.03440 60  PHE A CD2 
967  C CE1 . PHE A 60  ? 0.50662 0.47492 0.41868 0.11226  0.04647  -0.00862 60  PHE A CE1 
968  C CE2 . PHE A 60  ? 0.55956 0.50737 0.46518 0.14941  0.04924  -0.02751 60  PHE A CE2 
969  C CZ  . PHE A 60  ? 0.51594 0.46214 0.42035 0.13257  0.03968  -0.01338 60  PHE A CZ  
979  N N   . PRO A 61  ? 0.56938 0.53867 0.35374 0.07285  0.09816  -0.03646 61  PRO A N   
980  C CA  . PRO A 61  ? 0.67426 0.64315 0.40499 0.04910  0.10980  -0.03846 61  PRO A CA  
981  C C   . PRO A 61  ? 0.69611 0.71027 0.43070 0.03436  0.13704  -0.04003 61  PRO A C   
982  O O   . PRO A 61  ? 0.72805 0.73788 0.40896 0.00296  0.14406  -0.03109 61  PRO A O   
983  C CB  . PRO A 61  ? 0.67873 0.62683 0.37985 0.06027  0.12062  -0.06786 61  PRO A CB  
984  C CG  . PRO A 61  ? 0.64114 0.59466 0.39470 0.09525  0.12451  -0.08339 61  PRO A CG  
985  C CD  . PRO A 61  ? 0.61609 0.56872 0.40781 0.09846  0.10191  -0.05855 61  PRO A CD  
993  N N   . LYS A 62  ? 0.61199 0.66986 0.40491 0.05164  0.15081  -0.05012 62  LYS A N   
994  C CA  . LYS A 62  ? 0.63324 0.74697 0.44493 0.03405  0.17739  -0.05358 62  LYS A CA  
995  C C   . LYS A 62  ? 0.55873 0.69804 0.43146 0.04111  0.16451  -0.04130 62  LYS A C   
996  O O   . LYS A 62  ? 0.58889 0.71239 0.49151 0.06703  0.14323  -0.03993 62  LYS A O   
997  C CB  . LYS A 62  ? 0.57971 0.74282 0.41325 0.04930  0.21375  -0.09246 62  LYS A CB  
998  C CG  . LYS A 62  ? 0.80023 0.93172 0.57122 0.04274  0.22711  -0.10943 62  LYS A CG  
999  C CD  . LYS A 62  ? 0.89389 1.05193 0.63543 0.00891  0.25183  -0.10865 62  LYS A CD  
1000 C CE  . LYS A 62  ? 1.05744 1.17618 0.72032 -0.00717 0.25194  -0.11510 62  LYS A CE  
1001 N NZ  . LYS A 62  ? 1.13189 1.19685 0.72816 -0.03557 0.21930  -0.08158 62  LYS A NZ  
1015 N N   . PRO A 63  ? 0.56514 0.74049 0.44936 0.01260  0.17709  -0.03230 63  PRO A N   
1016 C CA  . PRO A 63  ? 0.50988 0.71557 0.45232 0.01603  0.16606  -0.02666 63  PRO A CA  
1017 C C   . PRO A 63  ? 0.48128 0.73092 0.48673 0.05466  0.16552  -0.04991 63  PRO A C   
1018 O O   . PRO A 63  ? 0.48286 0.77930 0.51432 0.06854  0.18958  -0.07643 63  PRO A O   
1019 C CB  . PRO A 63  ? 0.52354 0.76989 0.46578 -0.02633 0.18872  -0.02130 63  PRO A CB  
1020 C CG  . PRO A 63  ? 0.61203 0.81470 0.47419 -0.05779 0.19694  -0.00682 63  PRO A CG  
1021 C CD  . PRO A 63  ? 0.58780 0.77232 0.42358 -0.03095 0.20058  -0.02535 63  PRO A CD  
1029 N N   . ILE A 64  ? 0.46061 0.69251 0.48929 0.07241  0.13675  -0.04102 64  ILE A N   
1030 C CA  . ILE A 64  ? 0.42497 0.68807 0.50763 0.10706  0.12403  -0.05442 64  ILE A CA  
1031 C C   . ILE A 64  ? 0.36493 0.68542 0.49992 0.09551  0.11533  -0.05188 64  ILE A C   
1032 O O   . ILE A 64  ? 0.38790 0.77912 0.58558 0.10958  0.12131  -0.06988 64  ILE A O   
1033 C CB  . ILE A 64  ? 0.54246 0.74093 0.60114 0.12965  0.09552  -0.04502 64  ILE A CB  
1034 C CG1 . ILE A 64  ? 0.53686 0.67960 0.54447 0.13352  0.10208  -0.04783 64  ILE A CG1 
1035 C CG2 . ILE A 64  ? 0.50192 0.71711 0.60430 0.16624  0.07603  -0.05398 64  ILE A CG2 
1036 C CD1 . ILE A 64  ? 0.58076 0.73715 0.59543 0.15550  0.12200  -0.07454 64  ILE A CD1 
1048 N N   . ARG A 65  ? 0.40921 0.70276 0.52427 0.06998  0.10046  -0.03315 65  ARG A N   
1049 C CA  . ARG A 65  ? 0.37372 0.71273 0.52825 0.05160  0.08959  -0.03160 65  ARG A CA  
1050 C C   . ARG A 65  ? 0.40227 0.76263 0.55159 0.00729  0.11317  -0.02774 65  ARG A C   
1051 O O   . ARG A 65  ? 0.45011 0.76557 0.56650 -0.02122 0.10731  -0.01276 65  ARG A O   
1052 C CB  . ARG A 65  ? 0.43863 0.72959 0.56858 0.04769  0.06108  -0.01915 65  ARG A CB  
1053 C CG  . ARG A 65  ? 0.43919 0.72533 0.57871 0.07891  0.03255  -0.01980 65  ARG A CG  
1054 C CD  . ARG A 65  ? 0.41358 0.77611 0.61891 0.08868  0.01617  -0.02846 65  ARG A CD  
1055 N NE  . ARG A 65  ? 0.38097 0.77172 0.59849 0.05420  0.00519  -0.02623 65  ARG A NE  
1056 C CZ  . ARG A 65  ? 0.39681 0.75847 0.58585 0.04398  -0.02316 -0.01867 65  ARG A CZ  
1057 N NH1 . ARG A 65  ? 0.46381 0.76688 0.60647 0.06153  -0.04109 -0.00965 65  ARG A NH1 
1058 N NH2 . ARG A 65  ? 0.43746 0.82740 0.63867 0.00997  -0.03207 -0.02160 65  ARG A NH2 
1072 N N   . THR A 66  ? 0.39216 0.82004 0.57464 0.00035  0.14144  -0.04322 66  THR A N   
1073 C CA  . THR A 66  ? 0.36804 0.81658 0.53676 -0.04971 0.16832  -0.03825 66  THR A CA  
1074 C C   . THR A 66  ? 0.39397 0.87393 0.59537 -0.08442 0.15778  -0.03359 66  THR A C   
1075 O O   . THR A 66  ? 0.44194 0.91279 0.61778 -0.13350 0.17338  -0.02246 66  THR A O   
1076 C CB  . THR A 66  ? 0.36278 0.88760 0.56109 -0.05224 0.20838  -0.06261 66  THR A CB  
1077 O OG1 . THR A 66  ? 0.41031 1.01065 0.69680 -0.02507 0.20051  -0.08456 66  THR A OG1 
1078 C CG2 . THR A 66  ? 0.42079 0.90284 0.57488 -0.02331 0.21906  -0.07027 66  THR A CG2 
1086 N N   . ASP A 67  ? 0.35541 0.86482 0.60463 -0.06432 0.12893  -0.04029 67  ASP A N   
1087 C CA  . ASP A 67  ? 0.35628 0.89828 0.63562 -0.09960 0.11538  -0.03962 67  ASP A CA  
1088 C C   . ASP A 67  ? 0.37836 0.82920 0.59946 -0.12157 0.09609  -0.02254 67  ASP A C   
1089 O O   . ASP A 67  ? 0.41890 0.87951 0.65118 -0.15857 0.08719  -0.02302 67  ASP A O   
1090 C CB  . ASP A 67  ? 0.35526 0.96674 0.70540 -0.07094 0.08570  -0.05357 67  ASP A CB  
1091 C CG  . ASP A 67  ? 0.35600 0.90709 0.67593 -0.02697 0.05288  -0.04632 67  ASP A CG  
1092 O OD1 . ASP A 67  ? 0.35216 0.84710 0.63018 -0.00152 0.06250  -0.04160 67  ASP A OD1 
1093 O OD2 . ASP A 67  ? 0.32516 0.88340 0.65724 -0.02314 0.01706  -0.04484 67  ASP A OD2 
1098 N N   . VAL A 68  ? 0.39940 0.76569 0.56479 -0.10043 0.09011  -0.01156 68  VAL A N   
1099 C CA  . VAL A 68  ? 0.44716 0.73208 0.56979 -0.11327 0.07445  -0.00281 68  VAL A CA  
1100 C C   . VAL A 68  ? 0.52078 0.73918 0.59667 -0.13324 0.08724  0.01388  68  VAL A C   
1101 O O   . VAL A 68  ? 0.51765 0.74023 0.57651 -0.13126 0.10490  0.02113  68  VAL A O   
1102 C CB  . VAL A 68  ? 0.46589 0.70952 0.56860 -0.07644 0.05550  -0.00550 68  VAL A CB  
1103 C CG1 . VAL A 68  ? 0.45650 0.75502 0.59323 -0.05547 0.03641  -0.01490 68  VAL A CG1 
1104 C CG2 . VAL A 68  ? 0.53122 0.73730 0.60568 -0.04904 0.06483  0.00148  68  VAL A CG2 
1114 N N   . THR A 69  ? 0.56306 0.71446 0.61510 -0.15232 0.07532  0.01907  69  THR A N   
1115 C CA  . THR A 69  ? 0.64530 0.71779 0.65517 -0.16701 0.07520  0.03788  69  THR A CA  
1116 C C   . THR A 69  ? 0.59907 0.61030 0.59299 -0.13064 0.06070  0.03719  69  THR A C   
1117 O O   . THR A 69  ? 0.60125 0.62266 0.60964 -0.10548 0.05413  0.02074  69  THR A O   
1118 C CB  . THR A 69  ? 0.59847 0.62885 0.59996 -0.21119 0.06948  0.04209  69  THR A CB  
1119 O OG1 . THR A 69  ? 0.64840 0.65435 0.66165 -0.20304 0.05389  0.02262  69  THR A OG1 
1120 C CG2 . THR A 69  ? 0.54012 0.64277 0.56484 -0.25466 0.08579  0.04041  69  THR A CG2 
1128 N N   . GLY A 70  ? 0.65313 0.52543 0.60309 0.09338  0.13121  0.21007  70  GLY A N   
1129 C CA  . GLY A 70  ? 0.63626 0.51834 0.55271 0.08631  0.10038  0.18241  70  GLY A CA  
1130 C C   . GLY A 70  ? 0.62223 0.50675 0.59814 0.05930  0.09396  0.17787  70  GLY A C   
1131 O O   . GLY A 70  ? 0.69948 0.58420 0.71590 0.06977  0.11651  0.20573  70  GLY A O   
1135 N N   . MET A 71  ? 0.65064 0.53655 0.63409 0.02781  0.06571  0.14459  71  MET A N   
1136 C CA  . MET A 71  ? 0.54920 0.43785 0.57732 0.00661  0.05666  0.13540  71  MET A CA  
1137 C C   . MET A 71  ? 0.58913 0.48979 0.58892 0.01500  0.04347  0.12976  71  MET A C   
1138 O O   . MET A 71  ? 0.62491 0.53360 0.57169 0.03223  0.03268  0.12395  71  MET A O   
1139 C CB  . MET A 71  ? 0.58435 0.47135 0.62884 -0.02371 0.03589  0.10629  71  MET A CB  
1140 C CG  . MET A 71  ? 0.73421 0.61329 0.83111 -0.03628 0.04393  0.10822  71  MET A CG  
1141 S SD  . MET A 71  ? 0.68467 0.56682 0.78841 -0.06223 0.01834  0.07485  71  MET A SD  
1142 C CE  . MET A 71  ? 0.46083 0.35187 0.55567 -0.06704 0.00261  0.06032  71  MET A CE  
1152 N N   . ILE A 72  ? 0.60549 0.50793 0.64435 0.00381  0.04205  0.12871  72  ILE A N   
1153 C CA  . ILE A 72  ? 0.56517 0.48003 0.58666 0.00700  0.02800  0.12140  72  ILE A CA  
1154 C C   . ILE A 72  ? 0.55707 0.47747 0.56615 -0.01497 0.00119  0.09029  72  ILE A C   
1155 O O   . ILE A 72  ? 0.53556 0.45018 0.56903 -0.03550 -0.00351 0.07666  72  ILE A O   
1156 C CB  . ILE A 72  ? 0.61906 0.53189 0.68971 0.00530  0.03943  0.13322  72  ILE A CB  
1157 C CG1 . ILE A 72  ? 0.61739 0.52506 0.71106 0.02992  0.07157  0.17074  72  ILE A CG1 
1158 C CG2 . ILE A 72  ? 0.64929 0.57586 0.70456 0.00708  0.02466  0.12521  72  ILE A CG2 
1159 C CD1 . ILE A 72  ? 0.62448 0.53181 0.76193 0.03570  0.08472  0.18678  72  ILE A CD1 
1171 N N   . LEU A 73  ? 0.57670 0.50982 0.55171 -0.00766 -0.01617 0.07984  73  LEU A N   
1172 C CA  . LEU A 73  ? 0.57760 0.51846 0.55502 -0.02586 -0.03790 0.05620  73  LEU A CA  
1173 C C   . LEU A 73  ? 0.51073 0.46650 0.49584 -0.02178 -0.04623 0.05671  73  LEU A C   
1174 O O   . LEU A 73  ? 0.57215 0.53872 0.53540 -0.00034 -0.04991 0.06389  73  LEU A O   
1175 C CB  . LEU A 73  ? 0.60183 0.54504 0.55057 -0.02336 -0.05430 0.03941  73  LEU A CB  
1176 C CG  . LEU A 73  ? 0.54405 0.49709 0.50865 -0.03922 -0.07522 0.01843  73  LEU A CG  
1177 C CD1 . LEU A 73  ? 0.56278 0.51012 0.55688 -0.06147 -0.06856 0.01625  73  LEU A CD1 
1178 C CD2 . LEU A 73  ? 0.50252 0.45579 0.44795 -0.03391 -0.09299 -0.00082 73  LEU A CD2 
1190 N N   . GLU A 74  ? 0.56586 0.52375 0.57905 -0.03831 -0.04878 0.04991  74  GLU A N   
1191 C CA  . GLU A 74  ? 0.54889 0.52057 0.57502 -0.03553 -0.05418 0.05174  74  GLU A CA  
1192 C C   . GLU A 74  ? 0.49826 0.47856 0.54177 -0.05100 -0.06567 0.03781  74  GLU A C   
1193 O O   . GLU A 74  ? 0.49902 0.47241 0.54718 -0.06341 -0.06469 0.02986  74  GLU A O   
1194 C CB  . GLU A 74  ? 0.56022 0.52449 0.61015 -0.03318 -0.03787 0.06419  74  GLU A CB  
1195 C CG  . GLU A 74  ? 0.62826 0.58234 0.67834 -0.01824 -0.01988 0.08382  74  GLU A CG  
1196 C CD  . GLU A 74  ? 0.59394 0.54175 0.67951 -0.01359 -0.00444 0.09694  74  GLU A CD  
1197 O OE1 . GLU A 74  ? 0.65838 0.60165 0.76879 -0.02585 -0.00731 0.08419  74  GLU A OE1 
1198 O OE2 . GLU A 74  ? 0.59211 0.53937 0.68119 0.00560  0.01180  0.12067  74  GLU A OE2 
1205 N N   . GLU A 75  ? 0.52559 0.52263 0.58240 -0.04767 -0.07430 0.03828  75  GLU A N   
1206 C CA  . GLU A 75  ? 0.53116 0.53926 0.61587 -0.05912 -0.08092 0.03141  75  GLU A CA  
1207 C C   . GLU A 75  ? 0.56310 0.56633 0.66132 -0.06223 -0.06534 0.03760  75  GLU A C   
1208 O O   . GLU A 75  ? 0.55003 0.56024 0.65969 -0.05570 -0.06113 0.04487  75  GLU A O   
1209 C CB  . GLU A 75  ? 0.61542 0.64572 0.71752 -0.05300 -0.09763 0.02926  75  GLU A CB  
1210 C CG  . GLU A 75  ? 0.67840 0.72155 0.82523 -0.06445 -0.10118 0.02659  75  GLU A CG  
1211 C CD  . GLU A 75  ? 0.89938 0.96691 1.07685 -0.05965 -0.12167 0.02172  75  GLU A CD  
1212 O OE1 . GLU A 75  ? 0.82096 0.89691 0.97591 -0.04420 -0.13335 0.02076  75  GLU A OE1 
1213 O OE2 . GLU A 75  ? 0.99284 1.07274 1.22121 -0.06911 -0.12547 0.02033  75  GLU A OE2 
1220 N N   . GLY A 76  ? 0.45345 0.44539 0.54780 -0.06893 -0.05773 0.03333  76  GLY A N   
1221 C CA  . GLY A 76  ? 0.46437 0.45222 0.56259 -0.06552 -0.04655 0.03389  76  GLY A CA  
1222 C C   . GLY A 76  ? 0.46402 0.43950 0.55911 -0.05889 -0.04147 0.03320  76  GLY A C   
1223 O O   . GLY A 76  ? 0.44401 0.41368 0.53636 -0.05682 -0.04141 0.03808  76  GLY A O   
1227 N N   . ALA A 77  ? 0.38370 0.35508 0.48239 -0.05238 -0.03602 0.02735  77  ALA A N   
1228 C CA  . ALA A 77  ? 0.45552 0.41399 0.56520 -0.04593 -0.03291 0.02178  77  ALA A CA  
1229 C C   . ALA A 77  ? 0.48474 0.44908 0.60391 -0.03534 -0.02809 0.02501  77  ALA A C   
1230 O O   . ALA A 77  ? 0.46116 0.43957 0.57657 -0.03149 -0.02561 0.03053  77  ALA A O   
1231 C CB  . ALA A 77  ? 0.47915 0.42590 0.58706 -0.04369 -0.03630 0.00311  77  ALA A CB  
1237 N N   . PRO A 78  ? 0.46727 0.42088 0.60541 -0.02950 -0.02421 0.02395  78  PRO A N   
1238 C CA  . PRO A 78  ? 0.48018 0.43667 0.62737 -0.01751 -0.01878 0.02477  78  PRO A CA  
1239 C C   . PRO A 78  ? 0.49655 0.45455 0.62674 -0.00621 -0.01940 0.00987  78  PRO A C   
1240 O O   . PRO A 78  ? 0.44163 0.39183 0.56030 -0.00413 -0.02603 -0.00812 78  PRO A O   
1241 C CB  . PRO A 78  ? 0.45011 0.38845 0.62794 -0.01377 -0.01462 0.02098  78  PRO A CB  
1242 C CG  . PRO A 78  ? 0.45776 0.39093 0.64400 -0.02277 -0.01292 0.03187  78  PRO A CG  
1243 C CD  . PRO A 78  ? 0.49249 0.43020 0.65248 -0.03220 -0.02151 0.02450  78  PRO A CD  
1251 N N   . GLU A 79  ? 0.42325 0.39346 0.55094 0.00491  -0.01162 0.01909  79  GLU A N   
1252 C CA  . GLU A 79  ? 0.57789 0.55271 0.68352 0.02328  -0.00676 0.01164  79  GLU A CA  
1253 C C   . GLU A 79  ? 0.55479 0.51160 0.65211 0.03889  -0.01442 -0.01819 79  GLU A C   
1254 O O   . GLU A 79  ? 0.53805 0.48087 0.65877 0.04067  -0.01679 -0.02824 79  GLU A O   
1255 C CB  . GLU A 79  ? 0.53238 0.52269 0.64477 0.03542  0.00681  0.03027  79  GLU A CB  
1256 C CG  . GLU A 79  ? 0.52586 0.53777 0.65618 0.02277  0.01082  0.05497  79  GLU A CG  
1257 C CD  . GLU A 79  ? 0.59247 0.60848 0.74518 0.00615  0.00171  0.06315  79  GLU A CD  
1258 O OE1 . GLU A 79  ? 0.57054 0.57249 0.72502 0.00523  -0.00197 0.05634  79  GLU A OE1 
1259 O OE2 . GLU A 79  ? 0.59764 0.63187 0.76935 -0.00313 -0.00184 0.07640  79  GLU A OE2 
1266 N N   . GLY A 80  ? 0.56180 0.51963 0.62965 0.05222  -0.01943 -0.03347 80  GLY A N   
1267 C CA  . GLY A 80  ? 0.58593 0.52959 0.64520 0.06963  -0.03427 -0.06916 80  GLY A CA  
1268 C C   . GLY A 80  ? 0.53760 0.46795 0.61994 0.05271  -0.05136 -0.08828 80  GLY A C   
1269 O O   . GLY A 80  ? 0.56458 0.48331 0.65423 0.06508  -0.06876 -0.12277 80  GLY A O   
1273 N N   . THR A 81  ? 0.48975 0.42201 0.58703 0.02709  -0.04797 -0.06859 81  THR A N   
1274 C CA  . THR A 81  ? 0.51525 0.43614 0.63810 0.01211  -0.05941 -0.08056 81  THR A CA  
1275 C C   . THR A 81  ? 0.55993 0.48730 0.65399 0.01922  -0.07023 -0.09502 81  THR A C   
1276 O O   . THR A 81  ? 0.52465 0.46600 0.58649 0.02018  -0.06157 -0.07745 81  THR A O   
1277 C CB  . THR A 81  ? 0.44790 0.36952 0.58777 -0.01095 -0.04953 -0.05253 81  THR A CB  
1278 O OG1 . THR A 81  ? 0.57351 0.49282 0.73512 -0.01220 -0.03917 -0.03665 81  THR A OG1 
1279 C CG2 . THR A 81  ? 0.51672 0.42652 0.68724 -0.02340 -0.05586 -0.05942 81  THR A CG2 
1287 N N   . VAL A 82  ? 0.57285 0.49093 0.68512 0.02523  -0.08956 -0.12704 82  VAL A N   
1288 C CA  . VAL A 82  ? 0.55796 0.48410 0.64525 0.03423  -0.10279 -0.14236 82  VAL A CA  
1289 C C   . VAL A 82  ? 0.52058 0.44453 0.62982 0.00816  -0.09977 -0.12648 82  VAL A C   
1290 O O   . VAL A 82  ? 0.58260 0.49378 0.74340 -0.00706 -0.10380 -0.13079 82  VAL A O   
1291 C CB  . VAL A 82  ? 0.61160 0.53199 0.71173 0.05494  -0.13062 -0.18880 82  VAL A CB  
1292 C CG1 . VAL A 82  ? 0.62244 0.55278 0.70622 0.06166  -0.14706 -0.20378 82  VAL A CG1 
1293 C CG2 . VAL A 82  ? 0.63091 0.55578 0.69059 0.08978  -0.13354 -0.20607 82  VAL A CG2 
1303 N N   . VAL A 83  ? 0.50065 0.43650 0.57518 0.00495  -0.09002 -0.10604 83  VAL A N   
1304 C CA  . VAL A 83  ? 0.52159 0.45551 0.60809 -0.01622 -0.08578 -0.09077 83  VAL A CA  
1305 C C   . VAL A 83  ? 0.57001 0.51230 0.63596 -0.00630 -0.09644 -0.10315 83  VAL A C   
1306 O O   . VAL A 83  ? 0.60833 0.56013 0.64496 0.01939  -0.10600 -0.12074 83  VAL A O   
1307 C CB  . VAL A 83  ? 0.52651 0.46569 0.59789 -0.02944 -0.06743 -0.05874 83  VAL A CB  
1308 C CG1 . VAL A 83  ? 0.49503 0.43033 0.58312 -0.03440 -0.05947 -0.04726 83  VAL A CG1 
1309 C CG2 . VAL A 83  ? 0.60527 0.55936 0.63975 -0.01638 -0.05931 -0.04871 83  VAL A CG2 
1319 N N   . THR A 84  ? 0.53481 0.47466 0.61278 -0.02290 -0.09395 -0.09277 84  THR A N   
1320 C CA  . THR A 84  ? 0.57811 0.52681 0.63877 -0.01533 -0.10141 -0.09914 84  THR A CA  
1321 C C   . THR A 84  ? 0.56777 0.52015 0.60674 -0.02621 -0.08320 -0.07037 84  THR A C   
1322 O O   . THR A 84  ? 0.49006 0.43347 0.54560 -0.04642 -0.07408 -0.05472 84  THR A O   
1323 C CB  . THR A 84  ? 0.61680 0.55902 0.72253 -0.02366 -0.11699 -0.11652 84  THR A CB  
1324 O OG1 . THR A 84  ? 0.74597 0.67444 0.89091 -0.04628 -0.10454 -0.09872 84  THR A OG1 
1325 C CG2 . THR A 84  ? 0.55413 0.49605 0.68509 -0.00729 -0.14238 -0.15460 84  THR A CG2 
1333 N N   . LEU A 85  ? 0.54879 0.51432 0.55233 -0.00935 -0.07729 -0.06348 85  LEU A N   
1334 C CA  . LEU A 85  ? 0.57071 0.53921 0.56361 -0.01767 -0.06044 -0.03855 85  LEU A CA  
1335 C C   . LEU A 85  ? 0.53006 0.49921 0.52433 -0.01911 -0.06645 -0.04260 85  LEU A C   
1336 O O   . LEU A 85  ? 0.49171 0.47300 0.46614 0.00328  -0.07421 -0.05235 85  LEU A O   
1337 C CB  . LEU A 85  ? 0.53047 0.51289 0.49698 0.00323  -0.04513 -0.02270 85  LEU A CB  
1338 C CG  . LEU A 85  ? 0.57201 0.55924 0.53713 0.00072  -0.02610 0.00292  85  LEU A CG  
1339 C CD1 . LEU A 85  ? 0.57649 0.55143 0.56956 -0.02970 -0.02184 0.01248  85  LEU A CD1 
1340 C CD2 . LEU A 85  ? 0.60557 0.60690 0.55872 0.02389  -0.00575 0.02384  85  LEU A CD2 
1352 N N   . LEU A 86  ? 0.43744 0.39497 0.45238 -0.04156 -0.06287 -0.03483 86  LEU A N   
1353 C CA  . LEU A 86  ? 0.52461 0.48110 0.54830 -0.04490 -0.06743 -0.03748 86  LEU A CA  
1354 C C   . LEU A 86  ? 0.48268 0.44482 0.48560 -0.04073 -0.05351 -0.01975 86  LEU A C   
1355 O O   . LEU A 86  ? 0.45247 0.40523 0.46061 -0.05596 -0.04149 -0.00520 86  LEU A O   
1356 C CB  . LEU A 86  ? 0.51286 0.45430 0.56597 -0.06534 -0.06480 -0.03289 86  LEU A CB  
1357 C CG  . LEU A 86  ? 0.56928 0.50328 0.65580 -0.06983 -0.07216 -0.04314 86  LEU A CG  
1358 C CD1 . LEU A 86  ? 0.52955 0.45048 0.63977 -0.08364 -0.06095 -0.02830 86  LEU A CD1 
1359 C CD2 . LEU A 86  ? 0.58704 0.52725 0.69941 -0.05906 -0.09277 -0.06888 86  LEU A CD2 
1371 N N   . ILE A 87  ? 0.47085 0.44862 0.45073 -0.01640 -0.05522 -0.02161 87  ILE A N   
1372 C CA  . ILE A 87  ? 0.53299 0.51774 0.49779 -0.00724 -0.03816 -0.00063 87  ILE A CA  
1373 C C   . ILE A 87  ? 0.56186 0.54690 0.53296 -0.00916 -0.04403 -0.00358 87  ILE A C   
1374 O O   . ILE A 87  ? 0.53690 0.53194 0.50717 0.00419  -0.06362 -0.02301 87  ILE A O   
1375 C CB  . ILE A 87  ? 0.51689 0.52099 0.44968 0.02761  -0.03162 0.00577  87  ILE A CB  
1376 C CG1 . ILE A 87  ? 0.58298 0.58744 0.51342 0.03095  -0.02332 0.01112  87  ILE A CG1 
1377 C CG2 . ILE A 87  ? 0.57604 0.58738 0.50169 0.03932  -0.00834 0.03399  87  ILE A CG2 
1378 C CD1 . ILE A 87  ? 0.55001 0.54909 0.50227 0.01632  0.00107  0.03878  87  ILE A CD1 
1390 N N   . LYS A 88  ? 0.52400 0.49848 0.50536 -0.02460 -0.02891 0.01340  88  LYS A N   
1391 C CA  . LYS A 88  ? 0.48566 0.46222 0.46933 -0.02192 -0.02751 0.01796  88  LYS A CA  
1392 C C   . LYS A 88  ? 0.51903 0.50623 0.48656 -0.00271 -0.00805 0.04035  88  LYS A C   
1393 O O   . LYS A 88  ? 0.51163 0.49307 0.48642 -0.00746 0.01113  0.05807  88  LYS A O   
1394 C CB  . LYS A 88  ? 0.53306 0.48972 0.53729 -0.04674 -0.02125 0.02266  88  LYS A CB  
1395 C CG  . LYS A 88  ? 0.59950 0.54944 0.62523 -0.05791 -0.03510 0.00837  88  LYS A CG  
1396 C CD  . LYS A 88  ? 0.60691 0.54132 0.64495 -0.07149 -0.02478 0.01778  88  LYS A CD  
1397 C CE  . LYS A 88  ? 0.55755 0.48696 0.62533 -0.07849 -0.03200 0.01120  88  LYS A CE  
1398 N NZ  . LYS A 88  ? 0.59454 0.50763 0.66771 -0.08688 -0.01722 0.02408  88  LYS A NZ  
1412 N N   . ARG A 89  ? 0.51044 0.51434 0.46249 0.02055  -0.01260 0.04059  89  ARG A N   
1413 C CA  . ARG A 89  ? 0.47769 0.49327 0.41541 0.04385  0.00961  0.06710  89  ARG A CA  
1414 C C   . ARG A 89  ? 0.50094 0.50640 0.45714 0.03132  0.02056  0.07956  89  ARG A C   
1415 O O   . ARG A 89  ? 0.45799 0.45469 0.42859 0.01412  0.00690  0.06538  89  ARG A O   
1416 C CB  . ARG A 89  ? 0.46135 0.50549 0.36132 0.08654  -0.00150 0.06136  89  ARG A CB  
1417 C CG  . ARG A 89  ? 0.61272 0.66739 0.48677 0.10860  -0.00350 0.05623  89  ARG A CG  
1418 C CD  . ARG A 89  ? 0.63840 0.69401 0.51261 0.11987  0.03366  0.09385  89  ARG A CD  
1419 N NE  . ARG A 89  ? 0.63090 0.68401 0.50394 0.11881  0.03572  0.09080  89  ARG A NE  
1420 C CZ  . ARG A 89  ? 0.68416 0.75485 0.51854 0.15528  0.03101  0.08460  89  ARG A CZ  
1421 N NH1 . ARG A 89  ? 0.65432 0.74790 0.44342 0.19863  0.01985  0.07658  89  ARG A NH1 
1422 N NH2 . ARG A 89  ? 0.67823 0.74445 0.51746 0.15133  0.03632  0.08500  89  ARG A NH2 
1436 N N   . SER A 90  ? 0.48383 0.48980 0.44505 0.04145  0.04863  0.10893  90  SER A N   
1437 C CA  . SER A 90  ? 0.50647 0.50022 0.48814 0.03084  0.06236  0.12207  90  SER A CA  
1438 C C   . SER A 90  ? 0.52369 0.53105 0.49250 0.04365  0.04734  0.11392  90  SER A C   
1439 O O   . SER A 90  ? 0.59994 0.59378 0.58689 0.02677  0.04813  0.11286  90  SER A O   
1440 C CB  . SER A 90  ? 0.45991 0.45521 0.45657 0.04578  0.09668  0.15720  90  SER A CB  
1441 O OG  . SER A 90  ? 0.56499 0.58840 0.53065 0.08738  0.10538  0.17425  90  SER A OG  
1447 N N   . THR A 91  ? 0.50291 0.53801 0.44153 0.07589  0.03202  0.10636  91  THR A N   
1448 C CA  . THR A 91  ? 0.52690 0.57972 0.45964 0.09037  0.01085  0.09325  91  THR A CA  
1449 C C   . THR A 91  ? 0.49737 0.53776 0.46051 0.06061  -0.01298 0.06654  91  THR A C   
1450 O O   . THR A 91  ? 0.44172 0.48968 0.42037 0.06209  -0.02381 0.06154  91  THR A O   
1451 C CB  . THR A 91  ? 0.50808 0.59351 0.40187 0.13276  -0.00992 0.07951  91  THR A CB  
1452 O OG1 . THR A 91  ? 0.54063 0.62256 0.42843 0.12714  -0.02601 0.05663  91  THR A OG1 
1453 C CG2 . THR A 91  ? 0.51968 0.62323 0.37973 0.17369  0.01847  0.11382  91  THR A CG2 
1461 N N   . GLY A 92  ? 0.50768 0.53059 0.48364 0.03607  -0.01886 0.05278  92  GLY A N   
1462 C CA  . GLY A 92  ? 0.46697 0.48229 0.47345 0.01571  -0.03991 0.02991  92  GLY A CA  
1463 C C   . GLY A 92  ? 0.47750 0.50678 0.48458 0.02632  -0.06909 0.00081  92  GLY A C   
1464 O O   . GLY A 92  ? 0.50196 0.52210 0.54428 0.00784  -0.08301 -0.01608 92  GLY A O   
1468 N N   . GLU A 93  ? 0.53891 0.58957 0.50957 0.05862  -0.07692 -0.00452 93  GLU A N   
1469 C CA  . GLU A 93  ? 0.51192 0.57442 0.47866 0.07293  -0.10630 -0.03668 93  GLU A CA  
1470 C C   . GLU A 93  ? 0.54497 0.58635 0.52311 0.04899  -0.10067 -0.04015 93  GLU A C   
1471 O O   . GLU A 93  ? 0.51946 0.54839 0.48235 0.03993  -0.07480 -0.01725 93  GLU A O   
1472 C CB  . GLU A 93  ? 0.49449 0.58312 0.40644 0.11933  -0.10988 -0.03725 93  GLU A CB  
1473 C CG  . GLU A 93  ? 0.67471 0.77887 0.57605 0.14371  -0.14648 -0.07797 93  GLU A CG  
1474 C CD  . GLU A 93  ? 0.77258 0.90624 0.66900 0.17718  -0.18188 -0.10589 93  GLU A CD  
1475 O OE1 . GLU A 93  ? 0.82010 0.97072 0.69132 0.19974  -0.17142 -0.08538 93  GLU A OE1 
1476 O OE2 . GLU A 93  ? 0.86000 1.00060 0.78253 0.18213  -0.22160 -0.14970 93  GLU A OE2 
1483 N N   . LEU A 94  ? 0.61411 0.54119 0.54146 0.11913  -0.05007 0.00415  94  LEU A N   
1484 C CA  . LEU A 94  ? 0.62949 0.56379 0.57616 0.11112  -0.04799 0.00088  94  LEU A CA  
1485 C C   . LEU A 94  ? 0.61018 0.54455 0.54664 0.11329  -0.06322 -0.02506 94  LEU A C   
1486 O O   . LEU A 94  ? 0.66271 0.60153 0.61621 0.12152  -0.08508 -0.04114 94  LEU A O   
1487 C CB  . LEU A 94  ? 0.60685 0.55718 0.62547 0.10912  -0.05449 0.01507  94  LEU A CB  
1488 C CG  . LEU A 94  ? 0.69651 0.65561 0.73594 0.11194  -0.04274 0.04157  94  LEU A CG  
1489 C CD1 . LEU A 94  ? 0.59777 0.57826 0.71784 0.11055  -0.04934 0.06037  94  LEU A CD1 
1490 C CD2 . LEU A 94  ? 0.68490 0.64324 0.67904 0.11004  -0.01693 0.05279  94  LEU A CD2 
1502 N N   . MET A 95  ? 0.67634 0.60859 0.58569 0.10748  -0.05246 -0.03081 95  MET A N   
1503 C CA  . MET A 95  ? 0.64249 0.57826 0.53680 0.11136  -0.06259 -0.05522 95  MET A CA  
1504 C C   . MET A 95  ? 0.61946 0.56063 0.54084 0.10291  -0.05951 -0.05816 95  MET A C   
1505 O O   . MET A 95  ? 0.65588 0.59450 0.54416 0.09791  -0.04528 -0.05851 95  MET A O   
1506 C CB  . MET A 95  ? 0.71426 0.64408 0.54220 0.11514  -0.05033 -0.05685 95  MET A CB  
1507 C CG  . MET A 95  ? 0.87073 0.81237 0.67734 0.12810  -0.06493 -0.08055 95  MET A CG  
1508 S SD  . MET A 95  ? 1.01397 0.95762 0.75263 0.13184  -0.04559 -0.07580 95  MET A SD  
1509 C CE  . MET A 95  ? 1.03123 1.00098 0.75745 0.15055  -0.06551 -0.10862 95  MET A CE  
1519 N N   . PRO A 96  ? 0.56942 0.51910 0.55790 0.10106  -0.07312 -0.05805 96  PRO A N   
1520 C CA  . PRO A 96  ? 0.52706 0.48360 0.55041 0.09402  -0.07224 -0.05939 96  PRO A CA  
1521 C C   . PRO A 96  ? 0.54902 0.50694 0.55720 0.09980  -0.08189 -0.09092 96  PRO A C   
1522 O O   . PRO A 96  ? 0.57088 0.53264 0.59267 0.11067  -0.10331 -0.11706 96  PRO A O   
1523 C CB  . PRO A 96  ? 0.52447 0.49073 0.63426 0.09297  -0.08752 -0.04976 96  PRO A CB  
1524 C CG  . PRO A 96  ? 0.50119 0.46500 0.62146 0.10203  -0.10507 -0.05933 96  PRO A CG  
1525 C CD  . PRO A 96  ? 0.55251 0.50693 0.59654 0.10503  -0.08982 -0.05314 96  PRO A CD  
1533 N N   . LEU A 97  ? 0.53670 0.49445 0.51673 0.09404  -0.06650 -0.08979 97  LEU A N   
1534 C CA  . LEU A 97  ? 0.48548 0.44843 0.45096 0.10015  -0.07102 -0.11666 97  LEU A CA  
1535 C C   . LEU A 97  ? 0.48589 0.45482 0.50646 0.09327  -0.07352 -0.11772 97  LEU A C   
1536 O O   . LEU A 97  ? 0.54957 0.51907 0.57990 0.08159  -0.05916 -0.09235 97  LEU A O   
1537 C CB  . LEU A 97  ? 0.56481 0.52482 0.45861 0.09977  -0.05038 -0.11241 97  LEU A CB  
1538 C CG  . LEU A 97  ? 0.64501 0.59927 0.48583 0.10567  -0.04407 -0.10456 97  LEU A CG  
1539 C CD1 . LEU A 97  ? 0.65125 0.60279 0.43994 0.10236  -0.02217 -0.09414 97  LEU A CD1 
1540 C CD2 . LEU A 97  ? 0.68277 0.64718 0.51486 0.12283  -0.06347 -0.12803 97  LEU A CD2 
1552 N N   . ALA A 98  ? 0.46775 0.44334 0.52591 0.10193  -0.09280 -0.14805 98  ALA A N   
1553 C CA  . ALA A 98  ? 0.48017 0.46110 0.59638 0.09694  -0.09642 -0.15152 98  ALA A CA  
1554 C C   . ALA A 98  ? 0.54609 0.53066 0.61769 0.09664  -0.08035 -0.15890 98  ALA A C   
1555 O O   . ALA A 98  ? 0.59072 0.57886 0.60423 0.10705  -0.07630 -0.17726 98  ALA A O   
1556 C CB  . ALA A 98  ? 0.44329 0.42877 0.62887 0.10735  -0.12599 -0.18513 98  ALA A CB  
1562 N N   . ALA A 99  ? 0.55415 0.54144 0.65534 0.08549  -0.07064 -0.14137 99  ALA A N   
1563 C CA  . ALA A 99  ? 0.55321 0.54507 0.62401 0.08380  -0.05600 -0.14587 99  ALA A CA  
1564 C C   . ALA A 99  ? 0.56246 0.56123 0.70316 0.07829  -0.06075 -0.14337 99  ALA A C   
1565 O O   . ALA A 99  ? 0.53058 0.53147 0.72860 0.07006  -0.06514 -0.11956 99  ALA A O   
1566 C CB  . ALA A 99  ? 0.46895 0.45628 0.48145 0.07300  -0.03226 -0.11814 99  ALA A CB  
1572 N N   . ARG A 100 ? 0.53482 0.54020 0.67359 0.08417  -0.05900 -0.16552 100 ARG A N   
1573 C CA  . ARG A 100 ? 0.51020 0.52242 0.71014 0.07869  -0.06014 -0.16127 100 ARG A CA  
1574 C C   . ARG A 100 ? 0.44122 0.45719 0.60106 0.06754  -0.03723 -0.13763 100 ARG A C   
1575 O O   . ARG A 100 ? 0.48467 0.50276 0.58905 0.07191  -0.02477 -0.14881 100 ARG A O   
1576 C CB  . ARG A 100 ? 0.47995 0.49867 0.71273 0.09361  -0.07400 -0.20363 100 ARG A CB  
1577 C CG  . ARG A 100 ? 0.52005 0.54445 0.83105 0.08834  -0.07759 -0.19878 100 ARG A CG  
1578 C CD  . ARG A 100 ? 0.50294 0.53453 0.84145 0.10519  -0.08937 -0.24527 100 ARG A CD  
1579 N NE  . ARG A 100 ? 0.63764 0.66810 0.98000 0.12206  -0.11147 -0.28524 100 ARG A NE  
1580 C CZ  . ARG A 100 ? 0.75711 0.78526 1.17775 0.12115  -0.13691 -0.29324 100 ARG A CZ  
1581 N NH1 . ARG A 100 ? 0.69646 0.72076 1.20680 0.10806  -0.14291 -0.26777 100 ARG A NH1 
1582 N NH2 . ARG A 100 ? 0.72234 0.75911 1.13048 0.13070  -0.15620 -0.31950 100 ARG A NH2 
1596 N N   . MET A 101 ? 0.42874 0.44913 0.61960 0.05435  -0.03232 -0.10407 101 MET A N   
1597 C CA  . MET A 101 ? 0.41418 0.44006 0.57158 0.04356  -0.01438 -0.08246 101 MET A CA  
1598 C C   . MET A 101 ? 0.37986 0.41484 0.56615 0.04416  -0.01227 -0.09247 101 MET A C   
1599 O O   . MET A 101 ? 0.36991 0.40872 0.62065 0.05018  -0.02532 -0.10705 101 MET A O   
1600 C CB  . MET A 101 ? 0.41797 0.45264 0.59529 0.03282  -0.01151 -0.04482 101 MET A CB  
1601 C CG  . MET A 101 ? 0.35937 0.38762 0.51314 0.03391  -0.01260 -0.03476 101 MET A CG  
1602 S SD  . MET A 101 ? 0.43726 0.44850 0.49827 0.03646  -0.00128 -0.04937 101 MET A SD  
1603 C CE  . MET A 101 ? 0.46909 0.48629 0.49448 0.02527  0.01542  -0.03506 101 MET A CE  
1613 N N   . GLY A 102 ? 0.44969 0.48796 0.59329 0.03818  0.00362  -0.08535 102 GLY A N   
1614 C CA  . GLY A 102 ? 0.40152 0.44943 0.56500 0.03945  0.00843  -0.09469 102 GLY A CA  
1615 C C   . GLY A 102 ? 0.39142 0.44846 0.54951 0.02574  0.01960  -0.06814 102 GLY A C   
1616 O O   . GLY A 102 ? 0.42454 0.48892 0.60467 0.01672  0.01664  -0.04138 102 GLY A O   
1620 N N   . THR A 103 ? 0.46993 0.53034 0.59908 0.02539  0.03231  -0.07454 103 THR A N   
1621 C CA  . THR A 103 ? 0.38776 0.45859 0.52081 0.01311  0.04018  -0.05399 103 THR A CA  
1622 C C   . THR A 103 ? 0.42625 0.49478 0.52600 0.00179  0.04219  -0.03168 103 THR A C   
1623 O O   . THR A 103 ? 0.42976 0.48553 0.47960 0.00190  0.04765  -0.03506 103 THR A O   
1624 C CB  . THR A 103 ? 0.41231 0.48670 0.51961 0.01558  0.05451  -0.06449 103 THR A CB  
1625 O OG1 . THR A 103 ? 0.48852 0.57080 0.62827 0.02875  0.05306  -0.08738 103 THR A OG1 
1626 C CG2 . THR A 103 ? 0.40920 0.49361 0.52201 0.00186  0.06098  -0.04420 103 THR A CG2 
1634 N N   . HIS A 104 ? 0.41386 0.49769 0.54310 -0.00622 0.03726  -0.00913 104 HIS A N   
1635 C CA  . HIS A 104 ? 0.38729 0.47711 0.48475 -0.01542 0.03941  0.00760  104 HIS A CA  
1636 C C   . HIS A 104 ? 0.35997 0.45119 0.44037 -0.02261 0.04755  0.00422  104 HIS A C   
1637 O O   . HIS A 104 ? 0.37114 0.47082 0.48252 -0.02280 0.04990  0.00187  104 HIS A O   
1638 C CB  . HIS A 104 ? 0.34272 0.45769 0.47584 -0.01856 0.03154  0.03389  104 HIS A CB  
1639 C CG  . HIS A 104 ? 0.48144 0.60003 0.64432 -0.01216 0.02443  0.04493  104 HIS A CG  
1640 N ND1 . HIS A 104 ? 0.40481 0.53745 0.55532 -0.01147 0.02272  0.06531  104 HIS A ND1 
1641 C CD2 . HIS A 104 ? 0.44629 0.55871 0.65688 -0.00541 0.01797  0.03852  104 HIS A CD2 
1642 C CE1 . HIS A 104 ? 0.44066 0.57574 0.63199 -0.00556 0.01714  0.07539  104 HIS A CE1 
1643 N NE2 . HIS A 104 ? 0.44756 0.56880 0.67854 -0.00251 0.01266  0.05821  104 HIS A NE2 
1651 N N   . ALA A 105 ? 0.38979 0.47326 0.42795 -0.02830 0.05130  0.00401  105 ALA A N   
1652 C CA  . ALA A 105 ? 0.42609 0.51101 0.45902 -0.03618 0.05754  0.00254  105 ALA A CA  
1653 C C   . ALA A 105 ? 0.44980 0.52613 0.44765 -0.04279 0.05709  0.00176  105 ALA A C   
1654 O O   . ALA A 105 ? 0.45886 0.52267 0.42772 -0.03929 0.05603  -0.00162 105 ALA A O   
1655 C CB  . ALA A 105 ? 0.41408 0.48981 0.44423 -0.03077 0.06984  -0.00938 105 ALA A CB  
1661 N N   . THR A 106 ? 0.42634 0.50990 0.43310 -0.05207 0.05664  0.00356  106 THR A N   
1662 C CA  . THR A 106 ? 0.45727 0.52812 0.44308 -0.05869 0.05709  -0.00231 106 THR A CA  
1663 C C   . THR A 106 ? 0.48544 0.53901 0.46599 -0.05744 0.07212  -0.00462 106 THR A C   
1664 O O   . THR A 106 ? 0.48227 0.54390 0.48597 -0.05860 0.08037  -0.00072 106 THR A O   
1665 C CB  . THR A 106 ? 0.53398 0.62163 0.54019 -0.06880 0.04768  -0.00078 106 THR A CB  
1666 O OG1 . THR A 106 ? 0.66260 0.77619 0.67508 -0.06669 0.03518  0.00614  106 THR A OG1 
1667 C CG2 . THR A 106 ? 0.57995 0.65409 0.57191 -0.07488 0.04301  -0.01137 106 THR A CG2 
1675 N N   . MET A 107 ? 0.44082 0.47459 0.39225 -0.05344 0.07669  -0.00852 107 MET A N   
1676 C CA  . MET A 107 ? 0.49095 0.51401 0.43298 -0.04834 0.09190  -0.00602 107 MET A CA  
1677 C C   . MET A 107 ? 0.47872 0.48731 0.42034 -0.05582 0.09552  -0.00203 107 MET A C   
1678 O O   . MET A 107 ? 0.52028 0.51918 0.45625 -0.06110 0.08490  -0.00837 107 MET A O   
1679 C CB  . MET A 107 ? 0.51906 0.53326 0.43271 -0.03545 0.09416  -0.01102 107 MET A CB  
1680 C CG  . MET A 107 ? 0.61274 0.63855 0.53736 -0.02755 0.08840  -0.01683 107 MET A CG  
1681 S SD  . MET A 107 ? 0.58510 0.59937 0.48395 -0.01482 0.08395  -0.02495 107 MET A SD  
1682 C CE  . MET A 107 ? 0.54298 0.55537 0.43975 -0.02110 0.07117  -0.02009 107 MET A CE  
1692 N N   . LYS A 108 ? 0.48852 0.49819 0.44036 -0.05481 0.11081  0.00894  108 LYS A N   
1693 C CA  . LYS A 108 ? 0.52867 0.52454 0.48962 -0.06037 0.11696  0.01862  108 LYS A CA  
1694 C C   . LYS A 108 ? 0.49277 0.47856 0.42224 -0.04838 0.12728  0.02460  108 LYS A C   
1695 O O   . LYS A 108 ? 0.51881 0.51776 0.43472 -0.03617 0.14050  0.03122  108 LYS A O   
1696 C CB  . LYS A 108 ? 0.50279 0.51113 0.50242 -0.06633 0.12899  0.03455  108 LYS A CB  
1697 C CG  . LYS A 108 ? 0.66784 0.68410 0.70456 -0.08020 0.11581  0.02901  108 LYS A CG  
1698 C CD  . LYS A 108 ? 0.82433 0.82968 0.90078 -0.09336 0.11165  0.03429  108 LYS A CD  
1699 C CE  . LYS A 108 ? 0.96246 0.97905 1.07716 -0.09499 0.13138  0.05970  108 LYS A CE  
1700 N NZ  . LYS A 108 ? 1.04541 1.06533 1.21963 -0.11094 0.12203  0.06215  108 LYS A NZ  
1714 N N   . ILE A 109 ? 0.52414 0.48948 0.44177 -0.05011 0.12033  0.02060  109 ILE A N   
1715 C CA  . ILE A 109 ? 0.59285 0.54781 0.48323 -0.03943 0.12784  0.02752  109 ILE A CA  
1716 C C   . ILE A 109 ? 0.51232 0.45025 0.42679 -0.04660 0.13104  0.03979  109 ILE A C   
1717 O O   . ILE A 109 ? 0.52859 0.44961 0.45450 -0.05471 0.11763  0.02705  109 ILE A O   
1718 C CB  . ILE A 109 ? 0.54833 0.49438 0.40663 -0.03289 0.11611  0.01196  109 ILE A CB  
1719 C CG1 . ILE A 109 ? 0.62129 0.58404 0.46927 -0.02581 0.11245  0.00251  109 ILE A CG1 
1720 C CG2 . ILE A 109 ? 0.63001 0.56483 0.46408 -0.02264 0.12212  0.01963  109 ILE A CG2 
1721 C CD1 . ILE A 109 ? 0.68327 0.64115 0.51359 -0.02130 0.09991  -0.00932 109 ILE A CD1 
1733 N N   . GLN A 110 ? 0.60884 0.55398 0.53459 -0.04215 0.14868  0.06481  110 GLN A N   
1734 C CA  . GLN A 110 ? 0.58572 0.51632 0.54704 -0.04855 0.15360  0.08337  110 GLN A CA  
1735 C C   . GLN A 110 ? 0.59780 0.51732 0.60924 -0.06621 0.14050  0.07317  110 GLN A C   
1736 O O   . GLN A 110 ? 0.66156 0.55843 0.69358 -0.07295 0.12836  0.06272  110 GLN A O   
1737 C CB  . GLN A 110 ? 0.59920 0.50899 0.53908 -0.04244 0.14931  0.08125  110 GLN A CB  
1738 C CG  . GLN A 110 ? 0.62103 0.54441 0.51865 -0.02434 0.16195  0.09559  110 GLN A CG  
1739 C CD  . GLN A 110 ? 0.72280 0.62683 0.60551 -0.01847 0.15831  0.09793  110 GLN A CD  
1740 O OE1 . GLN A 110 ? 0.80872 0.68847 0.70395 -0.02622 0.14500  0.08196  110 GLN A OE1 
1741 N NE2 . GLN A 110 ? 0.83797 0.75603 0.69321 -0.00286 0.16984  0.11701  110 GLN A NE2 
1750 N N   . GLY A 111 ? 0.57762 0.51493 0.61051 -0.07254 0.14147  0.07347  111 GLY A N   
1751 C CA  . GLY A 111 ? 0.60589 0.53844 0.69005 -0.08861 0.12803  0.06441  111 GLY A CA  
1752 C C   . GLY A 111 ? 0.63656 0.56499 0.70555 -0.09332 0.10403  0.03023  111 GLY A C   
1753 O O   . GLY A 111 ? 0.67867 0.61542 0.77838 -0.10356 0.09183  0.01982  111 GLY A O   
1757 N N   . ALA A 112 ? 0.58044 0.50008 0.60376 -0.08486 0.09716  0.01452  112 ALA A N   
1758 C CA  . ALA A 112 ? 0.61196 0.53409 0.61735 -0.08582 0.07685  -0.01353 112 ALA A CA  
1759 C C   . ALA A 112 ? 0.55752 0.50279 0.53635 -0.08104 0.07695  -0.01495 112 ALA A C   
1760 O O   . ALA A 112 ? 0.53589 0.48928 0.49880 -0.07370 0.09111  -0.00136 112 ALA A O   
1761 C CB  . ALA A 112 ? 0.50801 0.41300 0.48318 -0.07793 0.07082  -0.02687 112 ALA A CB  
1767 N N   . THR A 113 ? 0.56037 0.51885 0.53776 -0.08392 0.05999  -0.03207 113 THR A N   
1768 C CA  . THR A 113 ? 0.53113 0.51300 0.49348 -0.07998 0.05776  -0.03103 113 THR A CA  
1769 C C   . THR A 113 ? 0.55000 0.53363 0.47391 -0.06956 0.05245  -0.03866 113 THR A C   
1770 O O   . THR A 113 ? 0.64312 0.62239 0.55530 -0.06760 0.04175  -0.05327 113 THR A O   
1771 C CB  . THR A 113 ? 0.55770 0.56058 0.54603 -0.08831 0.04316  -0.03837 113 THR A CB  
1772 O OG1 . THR A 113 ? 0.75594 0.76394 0.73220 -0.08681 0.02457  -0.05880 113 THR A OG1 
1773 C CG2 . THR A 113 ? 0.48157 0.48031 0.51673 -0.09997 0.04565  -0.03246 113 THR A CG2 
1781 N N   . VAL A 114 ? 0.52273 0.51427 0.43176 -0.06194 0.05955  -0.02965 114 VAL A N   
1782 C CA  . VAL A 114 ? 0.45328 0.44631 0.33461 -0.05188 0.05678  -0.03161 114 VAL A CA  
1783 C C   . VAL A 114 ? 0.43324 0.45081 0.32352 -0.04900 0.05312  -0.02458 114 VAL A C   
1784 O O   . VAL A 114 ? 0.43760 0.45991 0.34414 -0.04885 0.05971  -0.01786 114 VAL A O   
1785 C CB  . VAL A 114 ? 0.56641 0.54059 0.42878 -0.04398 0.06782  -0.02703 114 VAL A CB  
1786 C CG1 . VAL A 114 ? 0.56537 0.54215 0.40724 -0.03424 0.06367  -0.02818 114 VAL A CG1 
1787 C CG2 . VAL A 114 ? 0.62424 0.57563 0.48511 -0.04655 0.07238  -0.02828 114 VAL A CG2 
1797 N N   . GLY A 115 ? 0.37520 0.41109 0.25819 -0.04521 0.04318  -0.02501 115 GLY A N   
1798 C CA  . GLY A 115 ? 0.40473 0.46506 0.30262 -0.04115 0.04019  -0.01234 115 GLY A CA  
1799 C C   . GLY A 115 ? 0.46093 0.51470 0.35196 -0.03181 0.04403  -0.00672 115 GLY A C   
1800 O O   . GLY A 115 ? 0.44180 0.49012 0.31035 -0.02596 0.04323  -0.00934 115 GLY A O   
1804 N N   . GLY A 116 ? 0.40081 0.45534 0.31466 -0.02955 0.04710  -0.00114 116 GLY A N   
1805 C CA  . GLY A 116 ? 0.52282 0.57038 0.43783 -0.02081 0.04755  0.00072  116 GLY A CA  
1806 C C   . GLY A 116 ? 0.44983 0.49930 0.39760 -0.01771 0.04779  0.00024  116 GLY A C   
1807 O O   . GLY A 116 ? 0.43608 0.49880 0.41209 -0.02161 0.04713  0.00392  116 GLY A O   
1811 N N   . GLN A 117 ? 0.46828 0.50518 0.41433 -0.00957 0.04732  -0.00665 117 GLN A N   
1812 C CA  . GLN A 117 ? 0.43906 0.47797 0.41958 -0.00332 0.04374  -0.01357 117 GLN A CA  
1813 C C   . GLN A 117 ? 0.45530 0.47718 0.41026 0.00528  0.04713  -0.03175 117 GLN A C   
1814 O O   . GLN A 117 ? 0.51185 0.52193 0.44071 0.00918  0.04634  -0.03338 117 GLN A O   
1815 C CB  . GLN A 117 ? 0.44687 0.49695 0.46833 0.00056  0.03364  -0.00196 117 GLN A CB  
1816 C CG  . GLN A 117 ? 0.46206 0.51581 0.53662 0.00607  0.02630  -0.01023 117 GLN A CG  
1817 C CD  . GLN A 117 ? 0.44504 0.51097 0.57494 0.00841  0.01589  0.00683  117 GLN A CD  
1818 O OE1 . GLN A 117 ? 0.41954 0.49229 0.54165 0.00792  0.01582  0.02518  117 GLN A OE1 
1819 N NE2 . GLN A 117 ? 0.38528 0.45582 0.57674 0.01198  0.00741  0.00165  117 GLN A NE2 
1828 N N   . MET A 118 ? 0.47739 0.50186 0.43932 0.00993  0.05116  -0.04467 118 MET A N   
1829 C CA  . MET A 118 ? 0.49369 0.51147 0.43231 0.02244  0.05321  -0.06255 118 MET A CA  
1830 C C   . MET A 118 ? 0.53802 0.55452 0.50189 0.03220  0.03854  -0.07489 118 MET A C   
1831 O O   . MET A 118 ? 0.49852 0.52227 0.51372 0.03104  0.02844  -0.07307 118 MET A O   
1832 C CB  . MET A 118 ? 0.52524 0.55396 0.46657 0.02848  0.06186  -0.07394 118 MET A CB  
1833 C CG  . MET A 118 ? 0.60681 0.63527 0.51478 0.02418  0.07841  -0.06411 118 MET A CG  
1834 S SD  . MET A 118 ? 0.63524 0.68351 0.56285 0.02714  0.09051  -0.06764 118 MET A SD  
1835 C CE  . MET A 118 ? 0.60477 0.66501 0.54560 0.04888  0.08276  -0.09801 118 MET A CE  
1845 N N   . GLY A 119 ? 0.55520 0.56367 0.48849 0.04197  0.03643  -0.08588 119 GLY A N   
1846 C CA  . GLY A 119 ? 0.52518 0.53291 0.48317 0.05272  0.02027  -0.10253 119 GLY A CA  
1847 C C   . GLY A 119 ? 0.52960 0.54077 0.45339 0.06932  0.01978  -0.12617 119 GLY A C   
1848 O O   . GLY A 119 ? 0.58605 0.60064 0.46486 0.07211  0.03451  -0.12274 119 GLY A O   
1852 N N   . MET A 120 ? 0.56639 0.57991 0.51587 0.08146  0.00181  -0.14936 120 MET A N   
1853 C CA  . MET A 120 ? 0.61770 0.64060 0.53485 0.10104  -0.00318 -0.17610 120 MET A CA  
1854 C C   . MET A 120 ? 0.61067 0.62615 0.53720 0.10681  -0.02195 -0.18472 120 MET A C   
1855 O O   . MET A 120 ? 0.59151 0.60318 0.57833 0.10516  -0.03991 -0.19246 120 MET A O   
1856 C CB  . MET A 120 ? 0.66559 0.70576 0.60900 0.11551  -0.01000 -0.20857 120 MET A CB  
1857 C CG  . MET A 120 ? 0.73209 0.78919 0.64466 0.13931  -0.01910 -0.24055 120 MET A CG  
1858 S SD  . MET A 120 ? 1.04578 1.12713 0.98405 0.15233  -0.02294 -0.26744 120 MET A SD  
1859 C CE  . MET A 120 ? 0.65835 0.73016 0.69072 0.15218  -0.05380 -0.29531 120 MET A CE  
1869 N N   . LEU A 121 ? 0.63340 0.64801 0.50685 0.11347  -0.01794 -0.18069 121 LEU A N   
1870 C CA  . LEU A 121 ? 0.58066 0.59074 0.45997 0.12075  -0.03630 -0.18999 121 LEU A CA  
1871 C C   . LEU A 121 ? 0.59308 0.61813 0.49758 0.14016  -0.05935 -0.23210 121 LEU A C   
1872 O O   . LEU A 121 ? 0.63358 0.67857 0.51959 0.14982  -0.05513 -0.24361 121 LEU A O   
1873 C CB  . LEU A 121 ? 0.63413 0.64289 0.45087 0.12528  -0.02634 -0.17562 121 LEU A CB  
1874 C CG  . LEU A 121 ? 0.61022 0.60074 0.41080 0.10776  -0.00954 -0.13965 121 LEU A CG  
1875 C CD1 . LEU A 121 ? 0.73041 0.72056 0.47578 0.11380  0.00108  -0.12616 121 LEU A CD1 
1876 C CD2 . LEU A 121 ? 0.59697 0.57416 0.43965 0.09788  -0.02028 -0.12925 121 LEU A CD2 
1888 N N   . LEU A 122 ? 0.65073 0.71256 0.62716 0.01839  -0.07832 -0.15649 122 LEU A N   
1889 C CA  . LEU A 122 ? 0.65956 0.69473 0.60428 0.01201  -0.08608 -0.19204 122 LEU A CA  
1890 C C   . LEU A 122 ? 0.62743 0.67053 0.53919 -0.00162 -0.12372 -0.19723 122 LEU A C   
1891 O O   . LEU A 122 ? 0.83173 0.86049 0.67562 -0.00580 -0.13184 -0.21851 122 LEU A O   
1892 C CB  . LEU A 122 ? 0.59918 0.61095 0.59519 0.00803  -0.08499 -0.20619 122 LEU A CB  
1893 C CG  . LEU A 122 ? 0.64208 0.64669 0.67931 0.02333  -0.05662 -0.19489 122 LEU A CG  
1894 C CD1 . LEU A 122 ? 0.67523 0.65649 0.76366 0.01630  -0.06214 -0.19486 122 LEU A CD1 
1895 C CD2 . LEU A 122 ? 0.66693 0.65386 0.67771 0.03967  -0.02781 -0.21646 122 LEU A CD2 
1907 N N   . LEU A 132 ? 1.02832 1.13661 0.81872 0.04299  -0.27811 0.02791  132 LEU A N   
1908 C CA  . LEU A 132 ? 1.00868 1.13906 0.85628 0.03516  -0.27142 -0.00794 132 LEU A CA  
1909 C C   . LEU A 132 ? 1.03624 1.15863 0.91476 0.03301  -0.22251 -0.01606 132 LEU A C   
1910 O O   . LEU A 132 ? 1.05229 1.18038 0.95729 0.02549  -0.20837 -0.04310 132 LEU A O   
1911 C CB  . LEU A 132 ? 1.20648 1.33399 0.99612 0.02064  -0.28636 -0.03904 132 LEU A CB  
1912 C CG  . LEU A 132 ? 1.23947 1.38873 1.08794 0.00945  -0.30260 -0.07179 132 LEU A CG  
1913 C CD1 . LEU A 132 ? 1.15416 1.33951 1.07237 0.00929  -0.32952 -0.05543 132 LEU A CD1 
1914 C CD2 . LEU A 132 ? 1.12660 1.25681 0.90609 -0.00766 -0.30595 -0.10548 132 LEU A CD2 
1925 N N   . GLY A 133 ? 0.90983 1.01679 0.78604 0.03871  -0.20030 0.00889  133 GLY A N   
1926 C CA  . GLY A 133 ? 0.73190 0.83437 0.63546 0.03538  -0.16087 0.00458  133 GLY A CA  
1927 C C   . GLY A 133 ? 0.68524 0.78445 0.64175 0.04254  -0.15467 0.02112  133 GLY A C   
1928 O O   . GLY A 133 ? 0.72647 0.83340 0.72042 0.05290  -0.17647 0.02773  133 GLY A O   
1932 N N   . THR A 134 ? 0.57804 0.66712 0.54109 0.03726  -0.12549 0.02576  134 THR A N   
1933 C CA  . THR A 134 ? 0.58833 0.66704 0.59135 0.04082  -0.11874 0.03557  134 THR A CA  
1934 C C   . THR A 134 ? 0.58999 0.63849 0.56626 0.04193  -0.12015 0.06385  134 THR A C   
1935 O O   . THR A 134 ? 0.56317 0.60061 0.48839 0.03456  -0.11473 0.07835  134 THR A O   
1936 C CB  . THR A 134 ? 0.50557 0.58847 0.53138 0.03157  -0.09360 0.02488  134 THR A CB  
1937 O OG1 . THR A 134 ? 0.52293 0.60509 0.51979 0.02144  -0.07494 0.02994  134 THR A OG1 
1938 C CG2 . THR A 134 ? 0.50789 0.61101 0.56200 0.03148  -0.09268 0.00263  134 THR A CG2 
1946 N N   . THR A 135 ? 0.61298 0.64392 0.62301 0.05072  -0.12398 0.07122  135 THR A N   
1947 C CA  . THR A 135 ? 0.58246 0.57435 0.57592 0.05523  -0.12970 0.09885  135 THR A CA  
1948 C C   . THR A 135 ? 0.53205 0.49600 0.55306 0.05054  -0.11270 0.09629  135 THR A C   
1949 O O   . THR A 135 ? 0.49578 0.47478 0.54666 0.04664  -0.10062 0.07317  135 THR A O   
1950 C CB  . THR A 135 ? 0.59921 0.58923 0.60699 0.07796  -0.16106 0.11116  135 THR A CB  
1951 O OG1 . THR A 135 ? 0.57911 0.58304 0.65170 0.09214  -0.16091 0.09321  135 THR A OG1 
1952 C CG2 . THR A 135 ? 0.69959 0.71993 0.67940 0.07916  -0.18493 0.10855  135 THR A CG2 
1960 N N   . PRO A 136 ? 0.62229 0.54047 0.62951 0.04937  -0.11271 0.11939  136 PRO A N   
1961 C CA  . PRO A 136 ? 0.68740 0.57063 0.71416 0.04002  -0.09780 0.11318  136 PRO A CA  
1962 C C   . PRO A 136 ? 0.68608 0.56929 0.75529 0.05481  -0.09600 0.08744  136 PRO A C   
1963 O O   . PRO A 136 ? 0.73147 0.60414 0.80802 0.04130  -0.08161 0.06923  136 PRO A O   
1964 C CB  . PRO A 136 ? 0.63206 0.45777 0.63782 0.04155  -0.10411 0.14573  136 PRO A CB  
1965 C CG  . PRO A 136 ? 0.70803 0.54631 0.66473 0.03630  -0.11043 0.17144  136 PRO A CG  
1966 C CD  . PRO A 136 ? 0.65891 0.55027 0.62013 0.05044  -0.12473 0.15400  136 PRO A CD  
1974 N N   . GLY A 137 ? 0.56087 0.45807 0.65815 0.08090  -0.10966 0.08505  137 GLY A N   
1975 C CA  . GLY A 137 ? 0.48603 0.38483 0.62563 0.09579  -0.10026 0.06106  137 GLY A CA  
1976 C C   . GLY A 137 ? 0.45747 0.40317 0.61246 0.08904  -0.08888 0.03558  137 GLY A C   
1977 O O   . GLY A 137 ? 0.43237 0.38393 0.61855 0.10009  -0.07644 0.01648  137 GLY A O   
1981 N N   . ASP A 138 ? 0.38099 0.35676 0.51419 0.07152  -0.08958 0.03513  138 ASP A N   
1982 C CA  . ASP A 138 ? 0.43573 0.45133 0.58411 0.06663  -0.08257 0.01655  138 ASP A CA  
1983 C C   . ASP A 138 ? 0.44225 0.45198 0.57819 0.04959  -0.06525 0.00224  138 ASP A C   
1984 O O   . ASP A 138 ? 0.37497 0.41004 0.51935 0.04533  -0.05871 -0.00928 138 ASP A O   
1985 C CB  . ASP A 138 ? 0.42219 0.46834 0.55557 0.05990  -0.09373 0.02091  138 ASP A CB  
1986 C CG  . ASP A 138 ? 0.47797 0.53570 0.61604 0.07384  -0.11758 0.03258  138 ASP A CG  
1987 O OD1 . ASP A 138 ? 0.43345 0.48914 0.60535 0.09228  -0.12659 0.03651  138 ASP A OD1 
1988 O OD2 . ASP A 138 ? 0.46672 0.53621 0.57445 0.06730  -0.12821 0.03683  138 ASP A OD2 
1993 N N   . CYS A 139 ? 0.35772 0.33401 0.47335 0.03771  -0.06050 0.00416  139 CYS A N   
1994 C CA  . CYS A 139 ? 0.36764 0.34480 0.46940 0.01931  -0.05274 -0.00760 139 CYS A CA  
1995 C C   . CYS A 139 ? 0.42217 0.39269 0.52590 0.02414  -0.04042 -0.02750 139 CYS A C   
1996 O O   . CYS A 139 ? 0.35890 0.30665 0.47335 0.03878  -0.03241 -0.03573 139 CYS A O   
1997 C CB  . CYS A 139 ? 0.46426 0.41127 0.54935 0.00068  -0.05442 -0.00219 139 CYS A CB  
1998 S SG  . CYS A 139 ? 0.53885 0.51914 0.62249 -0.01503 -0.05766 0.01476  139 CYS A SG  
2004 N N   . GLY A 140 ? 0.41340 0.40314 0.50603 0.01321  -0.03705 -0.03407 140 GLY A N   
2005 C CA  . GLY A 140 ? 0.45465 0.44201 0.53815 0.01460  -0.02194 -0.04944 140 GLY A CA  
2006 C C   . GLY A 140 ? 0.40614 0.42785 0.51521 0.02298  -0.01409 -0.04820 140 GLY A C   
2007 O O   . GLY A 140 ? 0.33999 0.36419 0.43755 0.01913  0.00161  -0.05618 140 GLY A O   
2011 N N   . CYS A 141 ? 0.33110 0.37708 0.47046 0.03139  -0.02455 -0.03850 141 CYS A N   
2012 C CA  . CYS A 141 ? 0.37906 0.45694 0.54757 0.03404  -0.02080 -0.03900 141 CYS A CA  
2013 C C   . CYS A 141 ? 0.37389 0.45870 0.52516 0.01956  -0.02175 -0.03495 141 CYS A C   
2014 O O   . CYS A 141 ? 0.37219 0.45057 0.50308 0.01268  -0.03234 -0.02880 141 CYS A O   
2015 C CB  . CYS A 141 ? 0.35429 0.45275 0.55212 0.04387  -0.03834 -0.03233 141 CYS A CB  
2016 S SG  . CYS A 141 ? 0.34298 0.43805 0.57462 0.06679  -0.04252 -0.03107 141 CYS A SG  
2022 N N   . PRO A 142 ? 0.37310 0.47097 0.53746 0.01506  -0.00973 -0.03644 142 PRO A N   
2023 C CA  . PRO A 142 ? 0.39674 0.49048 0.54188 0.00294  -0.01020 -0.02888 142 PRO A CA  
2024 C C   . PRO A 142 ? 0.38980 0.49478 0.55499 0.00197  -0.02321 -0.02493 142 PRO A C   
2025 O O   . PRO A 142 ? 0.40144 0.52273 0.59679 0.00563  -0.02895 -0.03012 142 PRO A O   
2026 C CB  . PRO A 142 ? 0.42519 0.52088 0.57182 -0.00343 0.01363  -0.03012 142 PRO A CB  
2027 C CG  . PRO A 142 ? 0.34143 0.46287 0.53994 0.00574  0.02091  -0.03843 142 PRO A CG  
2028 C CD  . PRO A 142 ? 0.35545 0.47039 0.55454 0.02025  0.00866  -0.04340 142 PRO A CD  
2036 N N   . TYR A 143 ? 0.37940 0.47421 0.52730 -0.00235 -0.02971 -0.01693 143 TYR A N   
2037 C CA  . TYR A 143 ? 0.37733 0.47217 0.54091 -0.00265 -0.03621 -0.01554 143 TYR A CA  
2038 C C   . TYR A 143 ? 0.41012 0.49286 0.57548 -0.01241 -0.02607 -0.00715 143 TYR A C   
2039 O O   . TYR A 143 ? 0.40556 0.47440 0.54256 -0.01691 -0.02238 0.00511  143 TYR A O   
2040 C CB  . TYR A 143 ? 0.40139 0.49298 0.55626 0.00258  -0.04631 -0.01051 143 TYR A CB  
2041 C CG  . TYR A 143 ? 0.42657 0.52971 0.58052 0.00865  -0.05143 -0.01610 143 TYR A CG  
2042 C CD1 . TYR A 143 ? 0.40539 0.50917 0.54614 0.00695  -0.05206 -0.01422 143 TYR A CD1 
2043 C CD2 . TYR A 143 ? 0.47015 0.57797 0.63122 0.01458  -0.05330 -0.02335 143 TYR A CD2 
2044 C CE1 . TYR A 143 ? 0.41948 0.52885 0.55704 0.00940  -0.05457 -0.01415 143 TYR A CE1 
2045 C CE2 . TYR A 143 ? 0.49425 0.61101 0.64540 0.01787  -0.05356 -0.02514 143 TYR A CE2 
2046 C CZ  . TYR A 143 ? 0.46666 0.58448 0.60748 0.01447  -0.05427 -0.01783 143 TYR A CZ  
2047 O OH  . TYR A 143 ? 0.44843 0.57045 0.57731 0.01481  -0.05248 -0.01475 143 TYR A OH  
2057 N N   . ILE A 144 ? 0.40772 0.49371 0.60295 -0.01829 -0.02317 -0.01248 144 ILE A N   
2058 C CA  . ILE A 144 ? 0.39782 0.47247 0.60144 -0.03239 -0.00890 -0.00296 144 ILE A CA  
2059 C C   . ILE A 144 ? 0.42080 0.47717 0.64589 -0.03739 -0.01668 -0.00498 144 ILE A C   
2060 O O   . ILE A 144 ? 0.39340 0.45688 0.63571 -0.03325 -0.02939 -0.02208 144 ILE A O   
2061 C CB  . ILE A 144 ? 0.42445 0.52490 0.65820 -0.04016 0.00802  -0.00947 144 ILE A CB  
2062 C CG1 . ILE A 144 ? 0.45824 0.56625 0.66782 -0.03321 0.02137  -0.01057 144 ILE A CG1 
2063 C CG2 . ILE A 144 ? 0.56387 0.65651 0.81615 -0.05983 0.02637  0.00091  144 ILE A CG2 
2064 C CD1 . ILE A 144 ? 0.54764 0.63862 0.71961 -0.04365 0.04482  0.00204  144 ILE A CD1 
2076 N N   . TYR A 145 ? 0.47991 0.50688 0.69832 -0.04689 -0.00915 0.01233  145 TYR A N   
2077 C CA  . TYR A 145 ? 0.51621 0.51530 0.75921 -0.05485 -0.01292 0.01003  145 TYR A CA  
2078 C C   . TYR A 145 ? 0.53380 0.50694 0.77509 -0.07416 0.00436  0.03349  145 TYR A C   
2079 O O   . TYR A 145 ? 0.55548 0.52669 0.76210 -0.07690 0.01667  0.05380  145 TYR A O   
2080 C CB  . TYR A 145 ? 0.46441 0.43789 0.69909 -0.03681 -0.02760 0.00809  145 TYR A CB  
2081 C CG  . TYR A 145 ? 0.47599 0.41966 0.68874 -0.02870 -0.03010 0.03593  145 TYR A CG  
2082 C CD1 . TYR A 145 ? 0.46481 0.42480 0.64869 -0.01805 -0.03674 0.04875  145 TYR A CD1 
2083 C CD2 . TYR A 145 ? 0.58230 0.47882 0.80495 -0.03171 -0.03004 0.04990  145 TYR A CD2 
2084 C CE1 . TYR A 145 ? 0.45041 0.38788 0.61577 -0.01040 -0.04699 0.07592  145 TYR A CE1 
2085 C CE2 . TYR A 145 ? 0.60641 0.47484 0.81046 -0.02103 -0.03793 0.08009  145 TYR A CE2 
2086 C CZ  . TYR A 145 ? 0.48674 0.37952 0.66230 -0.01006 -0.04839 0.09338  145 TYR A CZ  
2087 O OH  . TYR A 145 ? 0.70760 0.57723 0.86603 0.00043  -0.06357 0.12509  145 TYR A OH  
2097 N N   . LYS A 146 ? 0.55818 0.50812 0.83248 -0.09038 0.00594  0.03006  146 LYS A N   
2098 C CA  . LYS A 146 ? 0.65631 0.57734 0.93392 -0.11391 0.02517  0.05478  146 LYS A CA  
2099 C C   . LYS A 146 ? 0.62207 0.47989 0.88363 -0.10838 0.01646  0.07487  146 LYS A C   
2100 O O   . LYS A 146 ? 0.57834 0.41223 0.85720 -0.09658 0.00012  0.05742  146 LYS A O   
2101 C CB  . LYS A 146 ? 0.59173 0.52731 0.92708 -0.14178 0.03386  0.04083  146 LYS A CB  
2102 C CG  . LYS A 146 ? 0.67999 0.61845 1.02451 -0.16981 0.06665  0.06556  146 LYS A CG  
2103 C CD  . LYS A 146 ? 0.75487 0.68464 1.16196 -0.20327 0.07214  0.06000  146 LYS A CD  
2104 C CE  . LYS A 146 ? 0.79516 0.77580 1.24681 -0.22952 0.10457  0.06580  146 LYS A CE  
2105 N NZ  . LYS A 146 ? 0.79554 0.80952 1.31614 -0.24826 0.09103  0.03981  146 LYS A NZ  
2119 N N   . ARG A 147 ? 0.75976 0.58805 0.98560 -0.11561 0.02811  0.11178  147 ARG A N   
2120 C CA  . ARG A 147 ? 0.74738 0.51087 0.95805 -0.10943 0.01860  0.14029  147 ARG A CA  
2121 C C   . ARG A 147 ? 0.80973 0.53567 1.02019 -0.14239 0.04225  0.16943  147 ARG A C   
2122 O O   . ARG A 147 ? 0.82262 0.54945 0.98725 -0.15426 0.06023  0.19953  147 ARG A O   
2123 C CB  . ARG A 147 ? 0.74531 0.50601 0.90458 -0.08577 0.00294  0.16499  147 ARG A CB  
2124 C CG  . ARG A 147 ? 0.85466 0.55375 1.00687 -0.07086 -0.01443 0.19629  147 ARG A CG  
2125 C CD  . ARG A 147 ? 0.80785 0.52116 0.92301 -0.04533 -0.03874 0.21522  147 ARG A CD  
2126 N NE  . ARG A 147 ? 0.77578 0.50876 0.82688 -0.06041 -0.03060 0.23451  147 ARG A NE  
2127 C CZ  . ARG A 147 ? 0.80542 0.57450 0.82231 -0.04889 -0.04669 0.23235  147 ARG A CZ  
2128 N NH1 . ARG A 147 ? 0.81433 0.61145 0.86186 -0.02357 -0.07059 0.21518  147 ARG A NH1 
2129 N NH2 . ARG A 147 ? 0.83671 0.61326 0.78677 -0.06527 -0.03619 0.24580  147 ARG A NH2 
2143 N N   . GLY A 148 ? 0.81309 0.50369 1.07105 -0.15980 0.04390  0.15953  148 GLY A N   
2144 C CA  . GLY A 148 ? 0.83844 0.49574 1.10873 -0.19762 0.06901  0.18521  148 GLY A CA  
2145 C C   . GLY A 148 ? 0.90590 0.62813 1.20581 -0.22591 0.09660  0.17236  148 GLY A C   
2146 O O   . GLY A 148 ? 0.92172 0.68080 1.28141 -0.23619 0.09135  0.13589  148 GLY A O   
2150 N N   . ASN A 149 ? 0.91815 0.65594 1.17643 -0.23771 0.12582  0.20164  149 ASN A N   
2151 C CA  . ASN A 149 ? 0.90344 0.70971 1.19056 -0.25734 0.15805  0.18944  149 ASN A CA  
2152 C C   . ASN A 149 ? 0.92037 0.77333 1.15724 -0.23355 0.16373  0.18239  149 ASN A C   
2153 O O   . ASN A 149 ? 0.86135 0.76955 1.11851 -0.24325 0.19382  0.17157  149 ASN A O   
2154 C CB  . ASN A 149 ? 0.90846 0.70041 1.18175 -0.29232 0.19349  0.21870  149 ASN A CB  
2155 C CG  . ASN A 149 ? 1.04154 0.86589 1.39019 -0.31942 0.19699  0.19518  149 ASN A CG  
2156 O OD1 . ASN A 149 ? 0.95371 0.84559 1.36267 -0.31603 0.19214  0.16041  149 ASN A OD1 
2157 N ND2 . ASN A 149 ? 0.93347 0.70865 1.27767 -0.34638 0.20202  0.21586  149 ASN A ND2 
2164 N N   . ASP A 150 ? 0.89433 0.72697 1.07270 -0.20303 0.13612  0.18672  150 ASP A N   
2165 C CA  . ASP A 150 ? 0.85076 0.71511 0.97394 -0.18391 0.13769  0.18081  150 ASP A CA  
2166 C C   . ASP A 150 ? 0.77406 0.67480 0.92517 -0.15609 0.10778  0.14368  150 ASP A C   
2167 O O   . ASP A 150 ? 0.73427 0.61249 0.88893 -0.13770 0.07582  0.13983  150 ASP A O   
2168 C CB  . ASP A 150 ? 0.89839 0.71555 0.93251 -0.17478 0.12526  0.21655  150 ASP A CB  
2169 C CG  . ASP A 150 ? 1.06574 0.83227 1.06216 -0.20168 0.14940  0.26134  150 ASP A CG  
2170 O OD1 . ASP A 150 ? 1.18530 0.97006 1.17473 -0.22711 0.19339  0.26723  150 ASP A OD1 
2171 O OD2 . ASP A 150 ? 1.10249 0.81024 1.07889 -0.19672 0.12634  0.29222  150 ASP A OD2 
2176 N N   . TYR A 151 ? 0.74470 0.69982 0.91655 -0.15206 0.12055  0.11796  151 TYR A N   
2177 C CA  . TYR A 151 ? 0.64870 0.63263 0.83088 -0.12631 0.09448  0.08963  151 TYR A CA  
2178 C C   . TYR A 151 ? 0.54756 0.51594 0.65919 -0.10856 0.07983  0.09858  151 TYR A C   
2179 O O   . TYR A 151 ? 0.61372 0.56660 0.66477 -0.11564 0.09546  0.11727  151 TYR A O   
2180 C CB  . TYR A 151 ? 0.59173 0.63182 0.81749 -0.12488 0.11017  0.06419  151 TYR A CB  
2181 C CG  . TYR A 151 ? 0.70474 0.77235 1.01262 -0.13600 0.10446  0.04745  151 TYR A CG  
2182 C CD1 . TYR A 151 ? 0.70851 0.78882 1.04348 -0.12170 0.07150  0.02465  151 TYR A CD1 
2183 C CD2 . TYR A 151 ? 0.69172 0.77325 1.04777 -0.16369 0.13135  0.05475  151 TYR A CD2 
2184 C CE1 . TYR A 151 ? 0.72503 0.82911 1.12593 -0.13399 0.05991  0.00770  151 TYR A CE1 
2185 C CE2 . TYR A 151 ? 0.68098 0.79133 1.11665 -0.17754 0.12004  0.03781  151 TYR A CE2 
2186 C CZ  . TYR A 151 ? 0.70408 0.82424 1.15842 -0.16238 0.08142  0.01344  151 TYR A CZ  
2187 O OH  . TYR A 151 ? 0.70057 0.84796 1.22538 -0.17831 0.06416  -0.00499 151 TYR A OH  
2197 N N   . VAL A 152 ? 0.53283 0.50616 0.65106 -0.08771 0.04936  0.08482  152 VAL A N   
2198 C CA  . VAL A 152 ? 0.51713 0.48209 0.58545 -0.07283 0.02908  0.09179  152 VAL A CA  
2199 C C   . VAL A 152 ? 0.51015 0.50844 0.59474 -0.05763 0.01748  0.06466  152 VAL A C   
2200 O O   . VAL A 152 ? 0.51015 0.52265 0.63886 -0.04976 0.00719  0.04799  152 VAL A O   
2201 C CB  . VAL A 152 ? 0.53350 0.46632 0.60009 -0.06246 0.00290  0.11087  152 VAL A CB  
2202 C CG1 . VAL A 152 ? 0.57325 0.51340 0.60855 -0.04698 -0.02269 0.11464  152 VAL A CG1 
2203 C CG2 . VAL A 152 ? 0.67269 0.56166 0.71446 -0.07666 0.01160  0.14498  152 VAL A CG2 
2213 N N   . VAL A 153 ? 0.49957 0.50482 0.54287 -0.05528 0.01922  0.06031  153 VAL A N   
2214 C CA  . VAL A 153 ? 0.45693 0.48231 0.50752 -0.04262 0.00548  0.04077  153 VAL A CA  
2215 C C   . VAL A 153 ? 0.46776 0.48504 0.49770 -0.03548 -0.02297 0.05136  153 VAL A C   
2216 O O   . VAL A 153 ? 0.46247 0.46119 0.44804 -0.04086 -0.03157 0.07014  153 VAL A O   
2217 C CB  . VAL A 153 ? 0.43435 0.46681 0.45938 -0.04461 0.02400  0.02592  153 VAL A CB  
2218 C CG1 . VAL A 153 ? 0.46570 0.47402 0.41984 -0.05596 0.03348  0.03757  153 VAL A CG1 
2219 C CG2 . VAL A 153 ? 0.42479 0.46680 0.45428 -0.03381 0.00770  0.00996  153 VAL A CG2 
2229 N N   . ILE A 154 ? 0.40508 0.43926 0.46809 -0.02389 -0.03798 0.04078  154 ILE A N   
2230 C CA  . ILE A 154 ? 0.38606 0.42424 0.45145 -0.01597 -0.06223 0.05005  154 ILE A CA  
2231 C C   . ILE A 154 ? 0.37545 0.43109 0.43491 -0.01633 -0.07188 0.03877  154 ILE A C   
2232 O O   . ILE A 154 ? 0.38472 0.45114 0.44999 -0.01399 -0.09254 0.04695  154 ILE A O   
2233 C CB  . ILE A 154 ? 0.36651 0.40857 0.47843 -0.00278 -0.06729 0.04894  154 ILE A CB  
2234 C CG1 . ILE A 154 ? 0.38292 0.44360 0.52069 0.00182  -0.05959 0.02644  154 ILE A CG1 
2235 C CG2 . ILE A 154 ? 0.39717 0.41169 0.51661 -0.00526 -0.05949 0.05952  154 ILE A CG2 
2236 C CD1 . ILE A 154 ? 0.38533 0.45029 0.55567 0.01519  -0.06279 0.01996  154 ILE A CD1 
2248 N N   . GLY A 155 ? 0.37790 0.43653 0.43253 -0.01931 -0.05867 0.02179  155 GLY A N   
2249 C CA  . GLY A 155 ? 0.38587 0.45109 0.43582 -0.02180 -0.06645 0.01208  155 GLY A CA  
2250 C C   . GLY A 155 ? 0.44539 0.51116 0.50759 -0.01766 -0.05150 -0.00334 155 GLY A C   
2251 O O   . GLY A 155 ? 0.37161 0.43832 0.44593 -0.01373 -0.03663 -0.00773 155 GLY A O   
2255 N N   . VAL A 156 ? 0.39431 0.46038 0.45841 -0.01928 -0.05759 -0.00916 156 VAL A N   
2256 C CA  . VAL A 156 ? 0.40867 0.46773 0.48058 -0.01362 -0.04793 -0.01938 156 VAL A CA  
2257 C C   . VAL A 156 ? 0.39105 0.45982 0.48223 -0.01163 -0.05547 -0.01492 156 VAL A C   
2258 O O   . VAL A 156 ? 0.35683 0.43539 0.45259 -0.01915 -0.06498 -0.00848 156 VAL A O   
2259 C CB  . VAL A 156 ? 0.41559 0.44712 0.45670 -0.01948 -0.04182 -0.03159 156 VAL A CB  
2260 C CG1 . VAL A 156 ? 0.45945 0.48211 0.47488 -0.02077 -0.02563 -0.03725 156 VAL A CG1 
2261 C CG2 . VAL A 156 ? 0.44523 0.46730 0.46564 -0.03511 -0.05904 -0.03119 156 VAL A CG2 
2271 N N   . HIS A 157 ? 0.39676 0.46546 0.50039 -0.00192 -0.05110 -0.01661 157 HIS A N   
2272 C CA  . HIS A 157 ? 0.36528 0.43965 0.47495 -0.00074 -0.05534 -0.00930 157 HIS A CA  
2273 C C   . HIS A 157 ? 0.43639 0.49210 0.53635 -0.01183 -0.05753 -0.00561 157 HIS A C   
2274 O O   . HIS A 157 ? 0.38976 0.41750 0.47927 -0.01245 -0.05565 -0.01192 157 HIS A O   
2275 C CB  . HIS A 157 ? 0.38064 0.45573 0.49696 0.01165  -0.05636 -0.00893 157 HIS A CB  
2276 C CG  . HIS A 157 ? 0.42681 0.50788 0.53485 0.01228  -0.05989 0.00005  157 HIS A CG  
2277 N ND1 . HIS A 157 ? 0.40254 0.50232 0.51017 0.01080  -0.05714 -0.00114 157 HIS A ND1 
2278 C CD2 . HIS A 157 ? 0.41297 0.48001 0.50756 0.01434  -0.06331 0.01119  157 HIS A CD2 
2279 C CE1 . HIS A 157 ? 0.47949 0.57945 0.56925 0.01079  -0.05560 0.00635  157 HIS A CE1 
2280 N NE2 . HIS A 157 ? 0.42149 0.50118 0.50061 0.01176  -0.06074 0.01665  157 HIS A NE2 
2288 N N   . THR A 158 ? 0.40755 0.47776 0.51503 -0.02112 -0.05906 0.00328  158 THR A N   
2289 C CA  . THR A 158 ? 0.40510 0.46080 0.51155 -0.03803 -0.06129 0.00818  158 THR A CA  
2290 C C   . THR A 158 ? 0.44045 0.50204 0.55135 -0.04237 -0.05356 0.02301  158 THR A C   
2291 O O   . THR A 158 ? 0.41620 0.45203 0.52196 -0.05480 -0.05243 0.03091  158 THR A O   
2292 C CB  . THR A 158 ? 0.40939 0.48288 0.52746 -0.05341 -0.07136 0.00618  158 THR A CB  
2293 O OG1 . THR A 158 ? 0.46962 0.53196 0.59390 -0.07517 -0.07582 0.00947  158 THR A OG1 
2294 C CG2 . THR A 158 ? 0.43657 0.55293 0.58275 -0.04768 -0.06998 0.01292  158 THR A CG2 
2302 N N   . ALA A 159 ? 0.40780 0.49738 0.52325 -0.03360 -0.04601 0.02661  159 ALA A N   
2303 C CA  . ALA A 159 ? 0.43577 0.53183 0.54498 -0.03935 -0.03315 0.04049  159 ALA A CA  
2304 C C   . ALA A 159 ? 0.41621 0.52977 0.51118 -0.02438 -0.02548 0.03675  159 ALA A C   
2305 O O   . ALA A 159 ? 0.41203 0.53612 0.51371 -0.01227 -0.03031 0.02321  159 ALA A O   
2306 C CB  . ALA A 159 ? 0.38961 0.51265 0.53081 -0.05851 -0.02489 0.04701  159 ALA A CB  
2312 N N   . ALA A 160 ? 0.47953 0.59109 0.54918 -0.02776 -0.01275 0.04895  160 ALA A N   
2313 C CA  . ALA A 160 ? 0.49768 0.62071 0.53937 -0.01713 -0.00360 0.04290  160 ALA A CA  
2314 C C   . ALA A 160 ? 0.55857 0.69044 0.58135 -0.02886 0.02197  0.05747  160 ALA A C   
2315 O O   . ALA A 160 ? 0.56231 0.67251 0.56896 -0.04221 0.02428  0.07915  160 ALA A O   
2316 C CB  . ALA A 160 ? 0.52768 0.62749 0.53264 -0.00546 -0.02262 0.04233  160 ALA A CB  
2322 N N   . ALA A 161 ? 0.91877 0.67593 0.61758 -0.01245 0.08500  0.00362  161 ALA A N   
2323 C CA  . ALA A 161 ? 1.00665 0.75027 0.67621 -0.02560 0.11913  0.01785  161 ALA A CA  
2324 C C   . ALA A 161 ? 1.10712 0.83657 0.67989 -0.03826 0.11124  0.02347  161 ALA A C   
2325 O O   . ALA A 161 ? 1.12102 0.85448 0.64633 -0.04456 0.10773  -0.00294 161 ALA A O   
2326 C CB  . ALA A 161 ? 0.97879 0.72707 0.67883 -0.03055 0.16964  -0.00229 161 ALA A CB  
2332 N N   . ARG A 162 ? 1.17944 0.89326 0.72387 -0.04327 0.10732  0.05899  162 ARG A N   
2333 C CA  . ARG A 162 ? 1.31577 1.01640 0.75936 -0.05674 0.10172  0.07455  162 ARG A CA  
2334 C C   . ARG A 162 ? 1.31796 1.01405 0.70178 -0.07601 0.15370  0.05090  162 ARG A C   
2335 O O   . ARG A 162 ? 1.19590 0.88910 0.62230 -0.08001 0.20336  0.04443  162 ARG A O   
2336 C CB  . ARG A 162 ? 1.38777 1.06874 0.82497 -0.05776 0.09502  0.12450  162 ARG A CB  
2337 C CG  . ARG A 162 ? 1.50846 1.17485 0.83619 -0.07129 0.08749  0.15418  162 ARG A CG  
2338 C CD  . ARG A 162 ? 1.65554 1.30017 0.99540 -0.06771 0.07305  0.21089  162 ARG A CD  
2339 N NE  . ARG A 162 ? 1.81911 1.46720 1.22888 -0.04799 0.02216  0.22114  162 ARG A NE  
2340 C CZ  . ARG A 162 ? 1.73964 1.37918 1.24174 -0.03846 0.02103  0.23270  162 ARG A CZ  
2341 N NH1 . ARG A 162 ? 1.66806 1.29739 1.21029 -0.04639 0.06216  0.24024  162 ARG A NH1 
2342 N NH2 . ARG A 162 ? 1.65784 1.30028 1.21794 -0.02214 -0.02108 0.23338  162 ARG A NH2 
2356 N N   . GLY A 163 ? 1.36321 1.06073 0.65252 -0.08903 0.14231  0.03488  163 GLY A N   
2357 C CA  . GLY A 163 ? 1.42167 1.11351 0.64259 -0.11106 0.19345  0.00380  163 GLY A CA  
2358 C C   . GLY A 163 ? 1.37900 1.08163 0.64866 -0.11117 0.22108  -0.05187 163 GLY A C   
2359 O O   . GLY A 163 ? 1.45283 1.14759 0.71522 -0.12491 0.28128  -0.07942 163 GLY A O   
2363 N N   . GLY A 164 ? 1.19176 0.91037 0.51728 -0.09637 0.18307  -0.06858 164 GLY A N   
2364 C CA  . GLY A 164 ? 1.07884 0.80517 0.46179 -0.09491 0.20870  -0.11554 164 GLY A CA  
2365 C C   . GLY A 164 ? 1.11947 0.86220 0.55898 -0.07787 0.16079  -0.12106 164 GLY A C   
2366 O O   . GLY A 164 ? 1.12862 0.87700 0.57339 -0.06585 0.11233  -0.09064 164 GLY A O   
2370 N N   . ASN A 165 ? 1.07756 0.82589 0.56626 -0.07735 0.18003  -0.16089 165 ASN A N   
2371 C CA  . ASN A 165 ? 1.02798 0.79067 0.57337 -0.06382 0.14551  -0.17048 165 ASN A CA  
2372 C C   . ASN A 165 ? 0.92178 0.68927 0.56538 -0.04162 0.14938  -0.14775 165 ASN A C   
2373 O O   . ASN A 165 ? 0.92984 0.70748 0.62411 -0.03064 0.13140  -0.15477 165 ASN A O   
2374 C CB  . ASN A 165 ? 1.06847 0.83331 0.62043 -0.07647 0.16470  -0.22423 165 ASN A CB  
2375 C CG  . ASN A 165 ? 1.28645 1.05658 0.74006 -0.09912 0.13975  -0.25105 165 ASN A CG  
2376 O OD1 . ASN A 165 ? 1.50092 1.28659 0.93554 -0.09639 0.08416  -0.24229 165 ASN A OD1 
2377 N ND2 . ASN A 165 ? 1.39918 1.17086 0.81982 -0.11498 0.17113  -0.27185 165 ASN A ND2 
2384 N N   . THR A 166 ? 0.79938 0.56198 0.46977 -0.03639 0.17159  -0.12046 166 THR A N   
2385 C CA  . THR A 166 ? 0.72787 0.50025 0.48540 -0.01818 0.17142  -0.09966 166 THR A CA  
2386 C C   . THR A 166 ? 0.73205 0.51286 0.49443 -0.00612 0.12152  -0.07663 166 THR A C   
2387 O O   . THR A 166 ? 0.68957 0.46474 0.41030 -0.00871 0.09727  -0.05741 166 THR A O   
2388 C CB  . THR A 166 ? 0.66814 0.43847 0.46038 -0.01800 0.20392  -0.07850 166 THR A CB  
2389 O OG1 . THR A 166 ? 0.80791 0.57026 0.61432 -0.02743 0.25807  -0.10313 166 THR A OG1 
2390 C CG2 . THR A 166 ? 0.63464 0.42184 0.51031 -0.00087 0.19189  -0.05442 166 THR A CG2 
2398 N N   . VAL A 167 ? 0.63787 0.43033 0.45364 0.00661  0.11019  -0.07815 167 VAL A N   
2399 C CA  . VAL A 167 ? 0.63102 0.43171 0.46168 0.01772  0.07302  -0.06169 167 VAL A CA  
2400 C C   . VAL A 167 ? 0.55898 0.37224 0.45012 0.02827  0.08092  -0.04570 167 VAL A C   
2401 O O   . VAL A 167 ? 0.57514 0.39278 0.50668 0.03079  0.10928  -0.04775 167 VAL A O   
2402 C CB  . VAL A 167 ? 0.60840 0.41404 0.43510 0.02058  0.04914  -0.08047 167 VAL A CB  
2403 C CG1 . VAL A 167 ? 0.67483 0.47499 0.44213 0.01061  0.02707  -0.08885 167 VAL A CG1 
2404 C CG2 . VAL A 167 ? 0.63116 0.44047 0.49422 0.02090  0.07442  -0.10281 167 VAL A CG2 
2414 N N   . ILE A 168 ? 0.52002 0.33979 0.41957 0.03375  0.05495  -0.02954 168 ILE A N   
2415 C CA  . ILE A 168 ? 0.48817 0.32473 0.43237 0.04043  0.05369  -0.01321 168 ILE A CA  
2416 C C   . ILE A 168 ? 0.49743 0.34306 0.44573 0.04783  0.03385  -0.01753 168 ILE A C   
2417 O O   . ILE A 168 ? 0.54067 0.38066 0.46831 0.04774  0.01180  -0.02531 168 ILE A O   
2418 C CB  . ILE A 168 ? 0.47804 0.31691 0.42990 0.03588  0.04363  0.00365  168 ILE A CB  
2419 C CG1 . ILE A 168 ? 0.57236 0.39965 0.51726 0.02688  0.06967  0.00868  168 ILE A CG1 
2420 C CG2 . ILE A 168 ? 0.48129 0.34467 0.47953 0.04015  0.03722  0.01847  168 ILE A CG2 
2421 C CD1 . ILE A 168 ? 0.54572 0.37833 0.52576 0.02762  0.10704  0.00634  168 ILE A CD1 
2433 N N   . CYS A 169 ? 0.51486 0.37380 0.49365 0.05438  0.04458  -0.01026 169 CYS A N   
2434 C CA  . CYS A 169 ? 0.51980 0.38810 0.49839 0.05996  0.03374  -0.01084 169 CYS A CA  
2435 C C   . CYS A 169 ? 0.48904 0.37827 0.47736 0.06099  0.01951  0.00940  169 CYS A C   
2436 O O   . CYS A 169 ? 0.44121 0.34535 0.46183 0.06461  0.02778  0.03158  169 CYS A O   
2437 C CB  . CYS A 169 ? 0.54533 0.41264 0.54700 0.06506  0.05685  -0.01304 169 CYS A CB  
2438 S SG  . CYS A 169 ? 0.53469 0.41359 0.53625 0.07097  0.05402  -0.00550 169 CYS A SG  
2444 N N   . ALA A 170 ? 0.47771 0.36955 0.44288 0.05714  -0.00277 0.00058  170 ALA A N   
2445 C CA  . ALA A 170 ? 0.47851 0.39310 0.44331 0.05386  -0.02046 0.01201  170 ALA A CA  
2446 C C   . ALA A 170 ? 0.44679 0.37701 0.40386 0.05899  -0.01579 0.02460  170 ALA A C   
2447 O O   . ALA A 170 ? 0.46305 0.38406 0.40147 0.06116  -0.00636 0.01105  170 ALA A O   
2448 C CB  . ALA A 170 ? 0.48371 0.39285 0.42741 0.04576  -0.04039 -0.00921 170 ALA A CB  
2454 N N   . THR A 171 ? 0.45084 0.40596 0.42687 0.06098  -0.02201 0.05398  171 THR A N   
2455 C CA  . THR A 171 ? 0.48861 0.46064 0.45438 0.06588  -0.01987 0.07747  171 THR A CA  
2456 C C   . THR A 171 ? 0.54931 0.55241 0.48471 0.05709  -0.05154 0.08652  171 THR A C   
2457 O O   . THR A 171 ? 0.53801 0.55243 0.48020 0.04804  -0.07431 0.07745  171 THR A O   
2458 C CB  . THR A 171 ? 0.47626 0.45381 0.49609 0.07732  -0.00186 0.11242  171 THR A CB  
2459 O OG1 . THR A 171 ? 0.52288 0.52329 0.58367 0.07715  -0.01803 0.13381  171 THR A OG1 
2460 C CG2 . THR A 171 ? 0.45208 0.39961 0.50025 0.08162  0.03018  0.09473  171 THR A CG2 
2468 N N   . GLN A 172 ? 0.57915 0.59654 0.47951 0.05786  -0.05208 0.10418  172 GLN A N   
2469 C CA  . GLN A 172 ? 0.71557 0.76667 0.57137 0.04707  -0.08343 0.11365  172 GLN A CA  
2470 C C   . GLN A 172 ? 0.78801 0.87257 0.67588 0.05482  -0.09977 0.16862  172 GLN A C   
2471 O O   . GLN A 172 ? 0.83470 0.91277 0.75282 0.06893  -0.07734 0.20275  172 GLN A O   
2472 C CB  . GLN A 172 ? 0.78263 0.82974 0.56659 0.04058  -0.07218 0.09938  172 GLN A CB  
2473 C CG  . GLN A 172 ? 0.90006 0.96838 0.62020 0.02106  -0.09945 0.07354  172 GLN A CG  
2474 C CD  . GLN A 172 ? 0.98152 1.05055 0.62333 0.01323  -0.08289 0.06516  172 GLN A CD  
2475 O OE1 . GLN A 172 ? 1.05966 1.13885 0.64252 -0.00498 -0.09477 0.03146  172 GLN A OE1 
2476 N NE2 . GLN A 172 ? 0.97509 1.03227 0.61824 0.02515  -0.05145 0.09342  172 GLN A NE2 
2485 N N   . GLY A 173 ? 0.87975 1.00092 0.77076 0.04542  -0.13957 0.17752  173 GLY A N   
2486 C CA  . GLY A 173 ? 0.93119 1.09125 0.86466 0.05319  -0.16321 0.23275  173 GLY A CA  
2487 C C   . GLY A 173 ? 1.04457 1.22578 0.91916 0.05448  -0.17232 0.27206  173 GLY A C   
2488 O O   . GLY A 173 ? 0.95109 1.11121 0.75935 0.05158  -0.14854 0.25845  173 GLY A O   
2492 N N   . SER A 174 ? 1.21252 1.43820 1.11639 0.05894  -0.20736 0.32550  174 SER A N   
2493 C CA  . SER A 174 ? 1.33208 1.58372 1.17738 0.05965  -0.22326 0.37428  174 SER A CA  
2494 C C   . SER A 174 ? 1.43417 1.71056 1.17243 0.03400  -0.25842 0.34187  174 SER A C   
2495 O O   . SER A 174 ? 1.50482 1.76682 1.14767 0.02362  -0.24043 0.32170  174 SER A O   
2496 C CB  . SER A 174 ? 1.35221 1.62467 1.28134 0.07303  -0.23749 0.42367  174 SER A CB  
2497 O OG  . SER A 174 ? 1.41938 1.73071 1.38311 0.06356  -0.28244 0.41521  174 SER A OG  
# 
