data_9D9T
# 
_entry.id   9D9T 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9D9T         pdb_00009d9t 10.2210/pdb9d9t/pdb 
WWPDB D_1000287586 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-19 ? 
2 'Structure model' 1 1 2025-03-12 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_citation.journal_volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9D9T 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              vprasad@bcm.edu 
_pdbx_contact_author.name_first         B.V.V 
_pdbx_contact_author.name_last          Prasad 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1172-2071 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Pham, S.H.'     1 0000-0001-6642-8796 
'Neetu, N.'      2 ?                   
'Sankaran, B.'   3 0000-0002-3266-8131 
'Prasad, B.V.V.' 4 0000-0002-1172-2071 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Virol. 
_citation.journal_id_ASTM           JOVIAM 
_citation.journal_id_CSD            0825 
_citation.journal_id_ISSN           1098-5514 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            99 
_citation.language                  ? 
_citation.page_first                e0175724 
_citation.page_last                 e0175724 
_citation.title                     
'Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1128/jvi.01757-24 
_citation.pdbx_database_id_PubMed   39873493 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Pham, S.'       1  ?                   
primary 'Zhao, B.'       2  ?                   
primary 'Neetu, N.'      3  ?                   
primary 'Sankaran, B.'   4  ?                   
primary 'Patil, K.'      5  ?                   
primary 'Ramani, S.'     6  0000-0001-5631-8534 
primary 'Song, Y.'       7  ?                   
primary 'Estes, M.K.'    8  0000-0002-4813-4249 
primary 'Palzkill, T.'   9  ?                   
primary 'Prasad, B.V.V.' 10 0000-0002-1172-2071 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Peptidase C37' 19398.352 1  ? R112A ? ? 
2 non-polymer syn 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
600.678   1  ? ?     ? ? 
3 non-polymer syn 'IODIDE ION' 126.904   5  ? ?     ? ? 
4 water       nat water 18.015    52 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GPAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQSAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAP
EGTVATLLIKRPTGELMPLAARMGTHATMKIQGATVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHT
AAARGGNTVICATQGSEGEATLE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GPAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQSAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAP
EGTVATLLIKRPTGELMPLAARMGTHATMKIQGATVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHT
AAARGGNTVICATQGSEGEATLE
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
AG7 
3 'IODIDE ION' IOD 
4 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   ALA n 
1 4   PRO n 
1 5   PRO n 
1 6   SER n 
1 7   ILE n 
1 8   TRP n 
1 9   SER n 
1 10  ARG n 
1 11  ILE n 
1 12  VAL n 
1 13  ASN n 
1 14  PHE n 
1 15  GLY n 
1 16  SER n 
1 17  GLY n 
1 18  TRP n 
1 19  GLY n 
1 20  PHE n 
1 21  TRP n 
1 22  VAL n 
1 23  SER n 
1 24  PRO n 
1 25  SER n 
1 26  LEU n 
1 27  PHE n 
1 28  ILE n 
1 29  THR n 
1 30  SER n 
1 31  THR n 
1 32  HIS n 
1 33  VAL n 
1 34  ILE n 
1 35  PRO n 
1 36  GLN n 
1 37  SER n 
1 38  ALA n 
1 39  LYS n 
1 40  GLU n 
1 41  PHE n 
1 42  PHE n 
1 43  GLY n 
1 44  VAL n 
1 45  PRO n 
1 46  ILE n 
1 47  LYS n 
1 48  GLN n 
1 49  ILE n 
1 50  GLN n 
1 51  ILE n 
1 52  HIS n 
1 53  LYS n 
1 54  SER n 
1 55  GLY n 
1 56  GLU n 
1 57  PHE n 
1 58  CYS n 
1 59  ARG n 
1 60  LEU n 
1 61  ARG n 
1 62  PHE n 
1 63  PRO n 
1 64  LYS n 
1 65  PRO n 
1 66  ILE n 
1 67  ARG n 
1 68  THR n 
1 69  ASP n 
1 70  VAL n 
1 71  THR n 
1 72  GLY n 
1 73  MET n 
1 74  ILE n 
1 75  LEU n 
1 76  GLU n 
1 77  GLU n 
1 78  GLY n 
1 79  ALA n 
1 80  PRO n 
1 81  GLU n 
1 82  GLY n 
1 83  THR n 
1 84  VAL n 
1 85  ALA n 
1 86  THR n 
1 87  LEU n 
1 88  LEU n 
1 89  ILE n 
1 90  LYS n 
1 91  ARG n 
1 92  PRO n 
1 93  THR n 
1 94  GLY n 
1 95  GLU n 
1 96  LEU n 
1 97  MET n 
1 98  PRO n 
1 99  LEU n 
1 100 ALA n 
1 101 ALA n 
1 102 ARG n 
1 103 MET n 
1 104 GLY n 
1 105 THR n 
1 106 HIS n 
1 107 ALA n 
1 108 THR n 
1 109 MET n 
1 110 LYS n 
1 111 ILE n 
1 112 GLN n 
1 113 GLY n 
1 114 ALA n 
1 115 THR n 
1 116 VAL n 
1 117 GLY n 
1 118 GLY n 
1 119 GLN n 
1 120 MET n 
1 121 GLY n 
1 122 MET n 
1 123 LEU n 
1 124 LEU n 
1 125 THR n 
1 126 GLY n 
1 127 SER n 
1 128 ASN n 
1 129 ALA n 
1 130 LYS n 
1 131 SER n 
1 132 MET n 
1 133 ASP n 
1 134 LEU n 
1 135 GLY n 
1 136 THR n 
1 137 THR n 
1 138 PRO n 
1 139 GLY n 
1 140 ASP n 
1 141 CYS n 
1 142 GLY n 
1 143 CYS n 
1 144 PRO n 
1 145 TYR n 
1 146 ILE n 
1 147 TYR n 
1 148 LYS n 
1 149 ARG n 
1 150 GLY n 
1 151 ASN n 
1 152 ASP n 
1 153 TYR n 
1 154 VAL n 
1 155 VAL n 
1 156 ILE n 
1 157 GLY n 
1 158 VAL n 
1 159 HIS n 
1 160 THR n 
1 161 ALA n 
1 162 ALA n 
1 163 ALA n 
1 164 ARG n 
1 165 GLY n 
1 166 GLY n 
1 167 ASN n 
1 168 THR n 
1 169 VAL n 
1 170 ILE n 
1 171 CYS n 
1 172 ALA n 
1 173 THR n 
1 174 GLN n 
1 175 GLY n 
1 176 SER n 
1 177 GLU n 
1 178 GLY n 
1 179 GLU n 
1 180 ALA n 
1 181 THR n 
1 182 LEU n 
1 183 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   183 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      Norovirus 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     142786 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
AG7 non-polymer         . 
;4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
;
'RUPINTRIVIR, bound form' 'C31 H41 F N4 O7' 600.678 
ALA 'L-peptide linking' y ALANINE ?                         'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE ?                         'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                         'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                         'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE ?                         'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                         'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                         'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE ?                         'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE ?                         'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER ?                         'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                         'C6 H13 N O2'     131.173 
IOD non-polymer         . 'IODIDE ION' ?                         'I -1'            126.904 
LEU 'L-peptide linking' y LEUCINE ?                         'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE ?                         'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE ?                         'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                         'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE ?                         'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE ?                         'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE ?                         'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                         'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE ?                         'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE ?                         'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -1  ?   ?   ?   A . n 
A 1 2   PRO 2   0   ?   ?   ?   A . n 
A 1 3   ALA 3   1   ?   ?   ?   A . n 
A 1 4   PRO 4   2   ?   ?   ?   A . n 
A 1 5   PRO 5   3   ?   ?   ?   A . n 
A 1 6   SER 6   4   4   SER SER A . n 
A 1 7   ILE 7   5   5   ILE ILE A . n 
A 1 8   TRP 8   6   6   TRP TRP A . n 
A 1 9   SER 9   7   7   SER SER A . n 
A 1 10  ARG 10  8   8   ARG ARG A . n 
A 1 11  ILE 11  9   9   ILE ILE A . n 
A 1 12  VAL 12  10  10  VAL VAL A . n 
A 1 13  ASN 13  11  11  ASN ASN A . n 
A 1 14  PHE 14  12  12  PHE PHE A . n 
A 1 15  GLY 15  13  13  GLY GLY A . n 
A 1 16  SER 16  14  14  SER SER A . n 
A 1 17  GLY 17  15  15  GLY GLY A . n 
A 1 18  TRP 18  16  16  TRP TRP A . n 
A 1 19  GLY 19  17  17  GLY GLY A . n 
A 1 20  PHE 20  18  18  PHE PHE A . n 
A 1 21  TRP 21  19  19  TRP TRP A . n 
A 1 22  VAL 22  20  20  VAL VAL A . n 
A 1 23  SER 23  21  21  SER SER A . n 
A 1 24  PRO 24  22  22  PRO PRO A . n 
A 1 25  SER 25  23  23  SER SER A . n 
A 1 26  LEU 26  24  24  LEU LEU A . n 
A 1 27  PHE 27  25  25  PHE PHE A . n 
A 1 28  ILE 28  26  26  ILE ILE A . n 
A 1 29  THR 29  27  27  THR THR A . n 
A 1 30  SER 30  28  28  SER SER A . n 
A 1 31  THR 31  29  29  THR THR A . n 
A 1 32  HIS 32  30  30  HIS HIS A . n 
A 1 33  VAL 33  31  31  VAL VAL A . n 
A 1 34  ILE 34  32  32  ILE ILE A . n 
A 1 35  PRO 35  33  33  PRO PRO A . n 
A 1 36  GLN 36  34  34  GLN GLN A . n 
A 1 37  SER 37  35  35  SER SER A . n 
A 1 38  ALA 38  36  36  ALA ALA A . n 
A 1 39  LYS 39  37  37  LYS LYS A . n 
A 1 40  GLU 40  38  38  GLU GLU A . n 
A 1 41  PHE 41  39  39  PHE PHE A . n 
A 1 42  PHE 42  40  40  PHE PHE A . n 
A 1 43  GLY 43  41  41  GLY GLY A . n 
A 1 44  VAL 44  42  42  VAL VAL A . n 
A 1 45  PRO 45  43  43  PRO PRO A . n 
A 1 46  ILE 46  44  44  ILE ILE A . n 
A 1 47  LYS 47  45  45  LYS LYS A . n 
A 1 48  GLN 48  46  46  GLN GLN A . n 
A 1 49  ILE 49  47  47  ILE ILE A . n 
A 1 50  GLN 50  48  48  GLN GLN A . n 
A 1 51  ILE 51  49  49  ILE ILE A . n 
A 1 52  HIS 52  50  50  HIS HIS A . n 
A 1 53  LYS 53  51  51  LYS LYS A . n 
A 1 54  SER 54  52  52  SER SER A . n 
A 1 55  GLY 55  53  53  GLY GLY A . n 
A 1 56  GLU 56  54  54  GLU GLU A . n 
A 1 57  PHE 57  55  55  PHE PHE A . n 
A 1 58  CYS 58  56  56  CYS CYS A . n 
A 1 59  ARG 59  57  57  ARG ARG A . n 
A 1 60  LEU 60  58  58  LEU LEU A . n 
A 1 61  ARG 61  59  59  ARG ARG A . n 
A 1 62  PHE 62  60  60  PHE PHE A . n 
A 1 63  PRO 63  61  61  PRO PRO A . n 
A 1 64  LYS 64  62  62  LYS LYS A . n 
A 1 65  PRO 65  63  63  PRO PRO A . n 
A 1 66  ILE 66  64  64  ILE ILE A . n 
A 1 67  ARG 67  65  65  ARG ARG A . n 
A 1 68  THR 68  66  66  THR THR A . n 
A 1 69  ASP 69  67  67  ASP ASP A . n 
A 1 70  VAL 70  68  68  VAL VAL A . n 
A 1 71  THR 71  69  69  THR THR A . n 
A 1 72  GLY 72  70  70  GLY GLY A . n 
A 1 73  MET 73  71  71  MET MET A . n 
A 1 74  ILE 74  72  72  ILE ILE A . n 
A 1 75  LEU 75  73  73  LEU LEU A . n 
A 1 76  GLU 76  74  74  GLU GLU A . n 
A 1 77  GLU 77  75  75  GLU GLU A . n 
A 1 78  GLY 78  76  76  GLY GLY A . n 
A 1 79  ALA 79  77  77  ALA ALA A . n 
A 1 80  PRO 80  78  78  PRO PRO A . n 
A 1 81  GLU 81  79  79  GLU GLU A . n 
A 1 82  GLY 82  80  80  GLY GLY A . n 
A 1 83  THR 83  81  81  THR THR A . n 
A 1 84  VAL 84  82  82  VAL VAL A . n 
A 1 85  ALA 85  83  83  ALA ALA A . n 
A 1 86  THR 86  84  84  THR THR A . n 
A 1 87  LEU 87  85  85  LEU LEU A . n 
A 1 88  LEU 88  86  86  LEU LEU A . n 
A 1 89  ILE 89  87  87  ILE ILE A . n 
A 1 90  LYS 90  88  88  LYS LYS A . n 
A 1 91  ARG 91  89  89  ARG ARG A . n 
A 1 92  PRO 92  90  90  PRO PRO A . n 
A 1 93  THR 93  91  91  THR THR A . n 
A 1 94  GLY 94  92  92  GLY GLY A . n 
A 1 95  GLU 95  93  93  GLU GLU A . n 
A 1 96  LEU 96  94  94  LEU LEU A . n 
A 1 97  MET 97  95  95  MET MET A . n 
A 1 98  PRO 98  96  96  PRO PRO A . n 
A 1 99  LEU 99  97  97  LEU LEU A . n 
A 1 100 ALA 100 98  98  ALA ALA A . n 
A 1 101 ALA 101 99  99  ALA ALA A . n 
A 1 102 ARG 102 100 100 ARG ARG A . n 
A 1 103 MET 103 101 101 MET MET A . n 
A 1 104 GLY 104 102 102 GLY GLY A . n 
A 1 105 THR 105 103 103 THR THR A . n 
A 1 106 HIS 106 104 104 HIS HIS A . n 
A 1 107 ALA 107 105 105 ALA ALA A . n 
A 1 108 THR 108 106 106 THR THR A . n 
A 1 109 MET 109 107 107 MET MET A . n 
A 1 110 LYS 110 108 108 LYS LYS A . n 
A 1 111 ILE 111 109 109 ILE ILE A . n 
A 1 112 GLN 112 110 110 GLN GLN A . n 
A 1 113 GLY 113 111 111 GLY GLY A . n 
A 1 114 ALA 114 112 112 ALA ALA A . n 
A 1 115 THR 115 113 113 THR THR A . n 
A 1 116 VAL 116 114 114 VAL VAL A . n 
A 1 117 GLY 117 115 115 GLY GLY A . n 
A 1 118 GLY 118 116 116 GLY GLY A . n 
A 1 119 GLN 119 117 117 GLN GLN A . n 
A 1 120 MET 120 118 118 MET MET A . n 
A 1 121 GLY 121 119 119 GLY GLY A . n 
A 1 122 MET 122 120 120 MET MET A . n 
A 1 123 LEU 123 121 121 LEU LEU A . n 
A 1 124 LEU 124 122 122 LEU LEU A . n 
A 1 125 THR 125 123 123 THR THR A . n 
A 1 126 GLY 126 124 ?   ?   ?   A . n 
A 1 127 SER 127 125 ?   ?   ?   A . n 
A 1 128 ASN 128 126 ?   ?   ?   A . n 
A 1 129 ALA 129 127 ?   ?   ?   A . n 
A 1 130 LYS 130 128 ?   ?   ?   A . n 
A 1 131 SER 131 129 ?   ?   ?   A . n 
A 1 132 MET 132 130 ?   ?   ?   A . n 
A 1 133 ASP 133 131 ?   ?   ?   A . n 
A 1 134 LEU 134 132 ?   ?   ?   A . n 
A 1 135 GLY 135 133 133 GLY GLY A . n 
A 1 136 THR 136 134 134 THR THR A . n 
A 1 137 THR 137 135 135 THR THR A . n 
A 1 138 PRO 138 136 136 PRO PRO A . n 
A 1 139 GLY 139 137 137 GLY GLY A . n 
A 1 140 ASP 140 138 138 ASP ASP A . n 
A 1 141 CYS 141 139 139 CYS CYS A . n 
A 1 142 GLY 142 140 140 GLY GLY A . n 
A 1 143 CYS 143 141 141 CYS CYS A . n 
A 1 144 PRO 144 142 142 PRO PRO A . n 
A 1 145 TYR 145 143 143 TYR TYR A . n 
A 1 146 ILE 146 144 144 ILE ILE A . n 
A 1 147 TYR 147 145 145 TYR TYR A . n 
A 1 148 LYS 148 146 146 LYS LYS A . n 
A 1 149 ARG 149 147 147 ARG ARG A . n 
A 1 150 GLY 150 148 148 GLY GLY A . n 
A 1 151 ASN 151 149 149 ASN ASN A . n 
A 1 152 ASP 152 150 150 ASP ASP A . n 
A 1 153 TYR 153 151 151 TYR TYR A . n 
A 1 154 VAL 154 152 152 VAL VAL A . n 
A 1 155 VAL 155 153 153 VAL VAL A . n 
A 1 156 ILE 156 154 154 ILE ILE A . n 
A 1 157 GLY 157 155 155 GLY GLY A . n 
A 1 158 VAL 158 156 156 VAL VAL A . n 
A 1 159 HIS 159 157 157 HIS HIS A . n 
A 1 160 THR 160 158 158 THR THR A . n 
A 1 161 ALA 161 159 159 ALA ALA A . n 
A 1 162 ALA 162 160 160 ALA ALA A . n 
A 1 163 ALA 163 161 161 ALA ALA A . n 
A 1 164 ARG 164 162 162 ARG ARG A . n 
A 1 165 GLY 165 163 163 GLY GLY A . n 
A 1 166 GLY 166 164 164 GLY GLY A . n 
A 1 167 ASN 167 165 165 ASN ASN A . n 
A 1 168 THR 168 166 166 THR THR A . n 
A 1 169 VAL 169 167 167 VAL VAL A . n 
A 1 170 ILE 170 168 168 ILE ILE A . n 
A 1 171 CYS 171 169 169 CYS CYS A . n 
A 1 172 ALA 172 170 170 ALA ALA A . n 
A 1 173 THR 173 171 171 THR THR A . n 
A 1 174 GLN 174 172 172 GLN GLN A . n 
A 1 175 GLY 175 173 ?   ?   ?   A . n 
A 1 176 SER 176 174 ?   ?   ?   A . n 
A 1 177 GLU 177 175 ?   ?   ?   A . n 
A 1 178 GLY 178 176 ?   ?   ?   A . n 
A 1 179 GLU 179 177 ?   ?   ?   A . n 
A 1 180 ALA 180 178 ?   ?   ?   A . n 
A 1 181 THR 181 179 ?   ?   ?   A . n 
A 1 182 LEU 182 180 ?   ?   ?   A . n 
A 1 183 GLU 183 181 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        AG7 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   AG7 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 AG7 1  201 201 AG7 AG7 A . 
C 3 IOD 1  202 1   IOD IOD A . 
D 3 IOD 1  203 3   IOD IOD A . 
E 3 IOD 1  204 5   IOD IOD A . 
F 3 IOD 1  205 6   IOD IOD A . 
G 3 IOD 1  206 7   IOD IOD A . 
H 4 HOH 1  301 3   HOH HOH A . 
H 4 HOH 2  302 276 HOH HOH A . 
H 4 HOH 3  303 236 HOH HOH A . 
H 4 HOH 4  304 618 HOH HOH A . 
H 4 HOH 5  305 109 HOH HOH A . 
H 4 HOH 6  306 86  HOH HOH A . 
H 4 HOH 7  307 30  HOH HOH A . 
H 4 HOH 8  308 40  HOH HOH A . 
H 4 HOH 9  309 51  HOH HOH A . 
H 4 HOH 10 310 5   HOH HOH A . 
H 4 HOH 11 311 161 HOH HOH A . 
H 4 HOH 12 312 157 HOH HOH A . 
H 4 HOH 13 313 83  HOH HOH A . 
H 4 HOH 14 314 90  HOH HOH A . 
H 4 HOH 15 315 278 HOH HOH A . 
H 4 HOH 16 316 23  HOH HOH A . 
H 4 HOH 17 317 29  HOH HOH A . 
H 4 HOH 18 318 9   HOH HOH A . 
H 4 HOH 19 319 390 HOH HOH A . 
H 4 HOH 20 320 504 HOH HOH A . 
H 4 HOH 21 321 229 HOH HOH A . 
H 4 HOH 22 322 339 HOH HOH A . 
H 4 HOH 23 323 7   HOH HOH A . 
H 4 HOH 24 324 12  HOH HOH A . 
H 4 HOH 25 325 406 HOH HOH A . 
H 4 HOH 26 326 263 HOH HOH A . 
H 4 HOH 27 327 17  HOH HOH A . 
H 4 HOH 28 328 380 HOH HOH A . 
H 4 HOH 29 329 167 HOH HOH A . 
H 4 HOH 30 330 470 HOH HOH A . 
H 4 HOH 31 331 279 HOH HOH A . 
H 4 HOH 32 332 1   HOH HOH A . 
H 4 HOH 33 333 19  HOH HOH A . 
H 4 HOH 34 334 398 HOH HOH A . 
H 4 HOH 35 335 21  HOH HOH A . 
H 4 HOH 36 336 519 HOH HOH A . 
H 4 HOH 37 337 543 HOH HOH A . 
H 4 HOH 38 338 69  HOH HOH A . 
H 4 HOH 39 339 87  HOH HOH A . 
H 4 HOH 40 340 10  HOH HOH A . 
H 4 HOH 41 341 551 HOH HOH A . 
H 4 HOH 42 342 343 HOH HOH A . 
H 4 HOH 43 343 561 HOH HOH A . 
H 4 HOH 44 344 394 HOH HOH A . 
H 4 HOH 45 345 180 HOH HOH A . 
H 4 HOH 46 346 549 HOH HOH A . 
H 4 HOH 47 347 447 HOH HOH A . 
H 4 HOH 48 348 555 HOH HOH A . 
H 4 HOH 49 349 619 HOH HOH A . 
H 4 HOH 50 350 332 HOH HOH A . 
H 4 HOH 51 351 598 HOH HOH A . 
H 4 HOH 52 352 20  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.21rc1_5156 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .            2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .            3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .            4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9D9T 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     98.350 
_cell.length_a_esd                 ? 
_cell.length_b                     98.350 
_cell.length_b_esd                 ? 
_cell.length_c                     46.280 
_cell.length_c_esd                 ? 
_cell.volume                       387679.387 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9D9T 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9D9T 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.33 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          63.07 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'0.02 M Magnesium chloride hexahydrate,  0.1M HEPES pH 7.5, 22 % w/v Poly(acrylic acid sodium salt) 5100, 0.2M potassium iodide' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-02-12 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.98 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL9-2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.98 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL9-2 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          41.27 
_reflns.entry_id                                       9D9T 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.0 
_reflns.d_resolution_low                               42.59 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     15510 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           87.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                21.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          22.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.076 
_reflns.pdbx_Rpim_I_all                                0.016 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   1 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.074 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.00 
_reflns_shell.d_res_low                                     2.03 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           3.6 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             871 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.231 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.929 
_reflns_shell.pdbx_CC_star                                  0.981 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               45.54 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9D9T 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.00 
_refine.ls_d_res_low                             42.59 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     15508 
_refine.ls_number_reflns_R_free                  782 
_refine.ls_number_reflns_R_work                  14726 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    87.69 
_refine.ls_percent_reflns_R_free                 5.04 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2144 
_refine.ls_R_factor_R_free                       0.2363 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2132 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 36.8508 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3019 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.00 
_refine_hist.d_res_low                        42.59 
_refine_hist.number_atoms_solvent             52 
_refine_hist.number_atoms_total               1304 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1204 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         48 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0049 ? 1277 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7066 ? 1730 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0500 ? 193  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0056 ? 218  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 9.6104 ? 177  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.00 2.13  . . 147 2747 99.69 . . . . 0.2583 . . . . . . . . . . . 0.3181 
'X-RAY DIFFRACTION' 2.13 2.29  . . 91  1654 59.80 . . . . 0.2949 . . . . . . . . . . . 0.3760 
'X-RAY DIFFRACTION' 2.29 2.52  . . 138 2732 98.22 . . . . 0.2935 . . . . . . . . . . . 0.3159 
'X-RAY DIFFRACTION' 2.52 2.88  . . 122 2312 82.90 . . . . 0.2631 . . . . . . . . . . . 0.3152 
'X-RAY DIFFRACTION' 2.88 3.63  . . 136 2625 93.43 . . . . 0.2236 . . . . . . . . . . . 0.2457 
'X-RAY DIFFRACTION' 3.64 42.59 . . 148 2656 91.87 . . . . 0.1721 . . . . . . . . . . . 0.1844 
# 
_struct.entry_id                     9D9T 
_struct.title                        'Human norovirus GII.4 Sydney protease R112A mutant in complex with rupintrivir' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9D9T 
_struct_keywords.text            'Viral protease with inhibitor, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    K4L8Z7_9CALI 
_struct_ref.pdbx_db_accession          K4L8Z7 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;APPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQSAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAA
ARGGNTVICATQGSEGEATLE
;
_struct_ref.pdbx_align_begin           1009 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9D9T 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 3 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 183 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             K4L8Z7 
_struct_ref_seq.db_align_beg                  1009 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1189 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       181 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9D9T GLY A 1   ? UNP K4L8Z7 ?   ?    'expression tag'      -1  1 
1 9D9T PRO A 2   ? UNP K4L8Z7 ?   ?    'expression tag'      0   2 
1 9D9T ALA A 114 ? UNP K4L8Z7 ARG 1120 'engineered mutation' 112 3 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                'HuNoV GII.4 Sydney protease R112A mutant in complex with Rupintrivir' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ILE A 7   ? SER A 9   ? ILE A 5   SER A 7   5 ? 3 
HELX_P HELX_P2 AA2 LYS A 47  ? ILE A 49  ? LYS A 45  ILE A 47  5 ? 3 
HELX_P HELX_P3 AA3 THR A 137 ? CYS A 141 ? THR A 135 CYS A 139 5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        none 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            141 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           AG7 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C19 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             139 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            AG7 
_struct_conn.ptnr2_auth_seq_id             201 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.773 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      AG7 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      141 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       AG7 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        201 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       139 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               C19 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        AG7 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 11  ? PHE A 14  ? ILE A 9   PHE A 12  
AA1 2 GLY A 17  ? TRP A 21  ? GLY A 15  TRP A 19  
AA1 3 LEU A 26  ? SER A 30  ? LEU A 24  SER A 28  
AA1 4 PHE A 57  ? ARG A 61  ? PHE A 55  ARG A 59  
AA1 5 GLN A 50  ? SER A 54  ? GLN A 48  SER A 52  
AA2 1 GLU A 40  ? PHE A 41  ? GLU A 38  PHE A 39  
AA2 2 VAL A 44  ? PRO A 45  ? VAL A 42  PRO A 43  
AA3 1 ILE A 74  ? LEU A 75  ? ILE A 72  LEU A 73  
AA3 2 ASP A 152 ? ALA A 162 ? ASP A 150 ALA A 160 
AA3 3 THR A 168 ? ALA A 172 ? THR A 166 ALA A 170 
AA3 4 ALA A 114 ? LEU A 123 ? ALA A 112 LEU A 121 
AA3 5 LEU A 96  ? ILE A 111 ? LEU A 94  ILE A 109 
AA3 6 VAL A 84  ? LYS A 90  ? VAL A 82  LYS A 88  
AA3 7 PRO A 144 ? ARG A 149 ? PRO A 142 ARG A 147 
AA3 8 ASP A 152 ? ALA A 162 ? ASP A 150 ALA A 160 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 14  ? N PHE A 12  O GLY A 17  ? O GLY A 15  
AA1 2 3 N PHE A 20  ? N PHE A 18  O ILE A 28  ? O ILE A 26  
AA1 3 4 N PHE A 27  ? N PHE A 25  O LEU A 60  ? O LEU A 58  
AA1 4 5 O ARG A 61  ? O ARG A 59  N GLN A 50  ? N GLN A 48  
AA2 1 2 N PHE A 41  ? N PHE A 39  O VAL A 44  ? O VAL A 42  
AA3 1 2 N ILE A 74  ? N ILE A 72  O VAL A 155 ? O VAL A 153 
AA3 2 3 N ALA A 161 ? N ALA A 159 O ILE A 170 ? O ILE A 168 
AA3 3 4 O CYS A 171 ? O CYS A 169 N GLN A 119 ? N GLN A 117 
AA3 4 5 O MET A 120 ? O MET A 118 N GLY A 104 ? N GLY A 102 
AA3 5 6 O MET A 97  ? O MET A 95  N ILE A 89  ? N ILE A 87  
AA3 6 7 N THR A 86  ? N THR A 84  O ILE A 146 ? O ILE A 144 
AA3 7 8 N ARG A 149 ? N ARG A 147 O ASP A 152 ? O ASP A 150 
# 
_pdbx_entry_details.entry_id                   9D9T 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    ARG 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     65 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             -114.33 
_pdbx_validate_torsion.psi             77.40 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    IOD 
_pdbx_struct_special_symmetry.auth_seq_id     205 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   F 
_pdbx_struct_special_symmetry.label_comp_id   IOD 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY -1  ? A GLY 1   
2  1 Y 1 A PRO 0   ? A PRO 2   
3  1 Y 1 A ALA 1   ? A ALA 3   
4  1 Y 1 A PRO 2   ? A PRO 4   
5  1 Y 1 A PRO 3   ? A PRO 5   
6  1 Y 1 A GLY 124 ? A GLY 126 
7  1 Y 1 A SER 125 ? A SER 127 
8  1 Y 1 A ASN 126 ? A ASN 128 
9  1 Y 1 A ALA 127 ? A ALA 129 
10 1 Y 1 A LYS 128 ? A LYS 130 
11 1 Y 1 A SER 129 ? A SER 131 
12 1 Y 1 A MET 130 ? A MET 132 
13 1 Y 1 A ASP 131 ? A ASP 133 
14 1 Y 1 A LEU 132 ? A LEU 134 
15 1 Y 1 A GLY 173 ? A GLY 175 
16 1 Y 1 A SER 174 ? A SER 176 
17 1 Y 1 A GLU 175 ? A GLU 177 
18 1 Y 1 A GLY 176 ? A GLY 178 
19 1 Y 1 A GLU 177 ? A GLU 179 
20 1 Y 1 A ALA 178 ? A ALA 180 
21 1 Y 1 A THR 179 ? A THR 181 
22 1 Y 1 A LEU 180 ? A LEU 182 
23 1 Y 1 A GLU 181 ? A GLU 183 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
AG7 C01  C N N 1   
AG7 C02  C N N 2   
AG7 O03  O N N 3   
AG7 C04  C N R 4   
AG7 C05  C N N 5   
AG7 C06  C Y N 6   
AG7 C07  C Y N 7   
AG7 C08  C Y N 8   
AG7 C09  C Y N 9   
AG7 C10  C Y N 10  
AG7 C11  C Y N 11  
AG7 N12  N N N 12  
AG7 C13  C N R 13  
AG7 C14  C N N 14  
AG7 C15  C N S 15  
AG7 C16  C N N 16  
AG7 N17  N N N 17  
AG7 O18  O N N 18  
AG7 C19  C N N 19  
AG7 C20  C N N 20  
AG7 C21  C N N 21  
AG7 O22  O N N 22  
AG7 O23  O N N 23  
AG7 C47  C N N 24  
AG7 O48  O N N 25  
AG7 C50  C N N 26  
AG7 C53  C N N 27  
AG7 C57  C N S 28  
AG7 N58  N N N 29  
AG7 C59  C N N 30  
AG7 O60  O N N 31  
AG7 C78  C N N 32  
AG7 C81  C N N 33  
AG7 F1   F N N 34  
AG7 C82  C N N 35  
AG7 C83  C N N 36  
AG7 C84  C N N 37  
AG7 C1   C Y N 38  
AG7 C2   C Y N 39  
AG7 C3   C Y N 40  
AG7 O4   O Y N 41  
AG7 N5   N Y N 42  
AG7 C4   C N N 43  
AG7 H2   H N N 44  
AG7 H3   H N N 45  
AG7 H27  H N N 46  
AG7 H28  H N N 47  
AG7 H29  H N N 48  
AG7 H30  H N N 49  
AG7 H31  H N N 50  
AG7 H33  H N N 51  
AG7 H34  H N N 52  
AG7 H49  H N N 53  
AG7 H91  H N N 54  
AG7 H35  H N N 55  
AG7 H36  H N N 56  
AG7 H94  H N N 57  
AG7 H39  H N N 58  
AG7 H191 H N N 59  
AG7 H192 H N N 60  
AG7 H41  H N N 61  
AG7 H42  H N N 62  
AG7 H51  H N N 63  
AG7 H52  H N N 64  
AG7 H53  H N N 65  
AG7 H54  H N N 66  
AG7 H56  H N N 67  
AG7 H77  H N N 68  
AG7 H61  H N N 69  
AG7 H79  H N N 70  
AG7 H82  H N N 71  
AG7 H84  H N N 72  
AG7 H85  H N N 73  
AG7 H86  H N N 74  
AG7 H87  H N N 75  
AG7 H88  H N N 76  
AG7 H89  H N N 77  
AG7 H90  H N N 78  
AG7 H92  H N N 79  
AG7 H93  H N N 80  
AG7 H8   H N N 81  
AG7 H5   H N N 82  
AG7 H6   H N N 83  
AG7 H7   H N N 84  
ALA N    N N N 85  
ALA CA   C N S 86  
ALA C    C N N 87  
ALA O    O N N 88  
ALA CB   C N N 89  
ALA OXT  O N N 90  
ALA H    H N N 91  
ALA H2   H N N 92  
ALA HA   H N N 93  
ALA HB1  H N N 94  
ALA HB2  H N N 95  
ALA HB3  H N N 96  
ALA HXT  H N N 97  
ARG N    N N N 98  
ARG CA   C N S 99  
ARG C    C N N 100 
ARG O    O N N 101 
ARG CB   C N N 102 
ARG CG   C N N 103 
ARG CD   C N N 104 
ARG NE   N N N 105 
ARG CZ   C N N 106 
ARG NH1  N N N 107 
ARG NH2  N N N 108 
ARG OXT  O N N 109 
ARG H    H N N 110 
ARG H2   H N N 111 
ARG HA   H N N 112 
ARG HB2  H N N 113 
ARG HB3  H N N 114 
ARG HG2  H N N 115 
ARG HG3  H N N 116 
ARG HD2  H N N 117 
ARG HD3  H N N 118 
ARG HE   H N N 119 
ARG HH11 H N N 120 
ARG HH12 H N N 121 
ARG HH21 H N N 122 
ARG HH22 H N N 123 
ARG HXT  H N N 124 
ASN N    N N N 125 
ASN CA   C N S 126 
ASN C    C N N 127 
ASN O    O N N 128 
ASN CB   C N N 129 
ASN CG   C N N 130 
ASN OD1  O N N 131 
ASN ND2  N N N 132 
ASN OXT  O N N 133 
ASN H    H N N 134 
ASN H2   H N N 135 
ASN HA   H N N 136 
ASN HB2  H N N 137 
ASN HB3  H N N 138 
ASN HD21 H N N 139 
ASN HD22 H N N 140 
ASN HXT  H N N 141 
ASP N    N N N 142 
ASP CA   C N S 143 
ASP C    C N N 144 
ASP O    O N N 145 
ASP CB   C N N 146 
ASP CG   C N N 147 
ASP OD1  O N N 148 
ASP OD2  O N N 149 
ASP OXT  O N N 150 
ASP H    H N N 151 
ASP H2   H N N 152 
ASP HA   H N N 153 
ASP HB2  H N N 154 
ASP HB3  H N N 155 
ASP HD2  H N N 156 
ASP HXT  H N N 157 
CYS N    N N N 158 
CYS CA   C N R 159 
CYS C    C N N 160 
CYS O    O N N 161 
CYS CB   C N N 162 
CYS SG   S N N 163 
CYS OXT  O N N 164 
CYS H    H N N 165 
CYS H2   H N N 166 
CYS HA   H N N 167 
CYS HB2  H N N 168 
CYS HB3  H N N 169 
CYS HG   H N N 170 
CYS HXT  H N N 171 
GLN N    N N N 172 
GLN CA   C N S 173 
GLN C    C N N 174 
GLN O    O N N 175 
GLN CB   C N N 176 
GLN CG   C N N 177 
GLN CD   C N N 178 
GLN OE1  O N N 179 
GLN NE2  N N N 180 
GLN OXT  O N N 181 
GLN H    H N N 182 
GLN H2   H N N 183 
GLN HA   H N N 184 
GLN HB2  H N N 185 
GLN HB3  H N N 186 
GLN HG2  H N N 187 
GLN HG3  H N N 188 
GLN HE21 H N N 189 
GLN HE22 H N N 190 
GLN HXT  H N N 191 
GLU N    N N N 192 
GLU CA   C N S 193 
GLU C    C N N 194 
GLU O    O N N 195 
GLU CB   C N N 196 
GLU CG   C N N 197 
GLU CD   C N N 198 
GLU OE1  O N N 199 
GLU OE2  O N N 200 
GLU OXT  O N N 201 
GLU H    H N N 202 
GLU H2   H N N 203 
GLU HA   H N N 204 
GLU HB2  H N N 205 
GLU HB3  H N N 206 
GLU HG2  H N N 207 
GLU HG3  H N N 208 
GLU HE2  H N N 209 
GLU HXT  H N N 210 
GLY N    N N N 211 
GLY CA   C N N 212 
GLY C    C N N 213 
GLY O    O N N 214 
GLY OXT  O N N 215 
GLY H    H N N 216 
GLY H2   H N N 217 
GLY HA2  H N N 218 
GLY HA3  H N N 219 
GLY HXT  H N N 220 
HIS N    N N N 221 
HIS CA   C N S 222 
HIS C    C N N 223 
HIS O    O N N 224 
HIS CB   C N N 225 
HIS CG   C Y N 226 
HIS ND1  N Y N 227 
HIS CD2  C Y N 228 
HIS CE1  C Y N 229 
HIS NE2  N Y N 230 
HIS OXT  O N N 231 
HIS H    H N N 232 
HIS H2   H N N 233 
HIS HA   H N N 234 
HIS HB2  H N N 235 
HIS HB3  H N N 236 
HIS HD1  H N N 237 
HIS HD2  H N N 238 
HIS HE1  H N N 239 
HIS HE2  H N N 240 
HIS HXT  H N N 241 
HOH O    O N N 242 
HOH H1   H N N 243 
HOH H2   H N N 244 
ILE N    N N N 245 
ILE CA   C N S 246 
ILE C    C N N 247 
ILE O    O N N 248 
ILE CB   C N S 249 
ILE CG1  C N N 250 
ILE CG2  C N N 251 
ILE CD1  C N N 252 
ILE OXT  O N N 253 
ILE H    H N N 254 
ILE H2   H N N 255 
ILE HA   H N N 256 
ILE HB   H N N 257 
ILE HG12 H N N 258 
ILE HG13 H N N 259 
ILE HG21 H N N 260 
ILE HG22 H N N 261 
ILE HG23 H N N 262 
ILE HD11 H N N 263 
ILE HD12 H N N 264 
ILE HD13 H N N 265 
ILE HXT  H N N 266 
IOD I    I N N 267 
LEU N    N N N 268 
LEU CA   C N S 269 
LEU C    C N N 270 
LEU O    O N N 271 
LEU CB   C N N 272 
LEU CG   C N N 273 
LEU CD1  C N N 274 
LEU CD2  C N N 275 
LEU OXT  O N N 276 
LEU H    H N N 277 
LEU H2   H N N 278 
LEU HA   H N N 279 
LEU HB2  H N N 280 
LEU HB3  H N N 281 
LEU HG   H N N 282 
LEU HD11 H N N 283 
LEU HD12 H N N 284 
LEU HD13 H N N 285 
LEU HD21 H N N 286 
LEU HD22 H N N 287 
LEU HD23 H N N 288 
LEU HXT  H N N 289 
LYS N    N N N 290 
LYS CA   C N S 291 
LYS C    C N N 292 
LYS O    O N N 293 
LYS CB   C N N 294 
LYS CG   C N N 295 
LYS CD   C N N 296 
LYS CE   C N N 297 
LYS NZ   N N N 298 
LYS OXT  O N N 299 
LYS H    H N N 300 
LYS H2   H N N 301 
LYS HA   H N N 302 
LYS HB2  H N N 303 
LYS HB3  H N N 304 
LYS HG2  H N N 305 
LYS HG3  H N N 306 
LYS HD2  H N N 307 
LYS HD3  H N N 308 
LYS HE2  H N N 309 
LYS HE3  H N N 310 
LYS HZ1  H N N 311 
LYS HZ2  H N N 312 
LYS HZ3  H N N 313 
LYS HXT  H N N 314 
MET N    N N N 315 
MET CA   C N S 316 
MET C    C N N 317 
MET O    O N N 318 
MET CB   C N N 319 
MET CG   C N N 320 
MET SD   S N N 321 
MET CE   C N N 322 
MET OXT  O N N 323 
MET H    H N N 324 
MET H2   H N N 325 
MET HA   H N N 326 
MET HB2  H N N 327 
MET HB3  H N N 328 
MET HG2  H N N 329 
MET HG3  H N N 330 
MET HE1  H N N 331 
MET HE2  H N N 332 
MET HE3  H N N 333 
MET HXT  H N N 334 
PHE N    N N N 335 
PHE CA   C N S 336 
PHE C    C N N 337 
PHE O    O N N 338 
PHE CB   C N N 339 
PHE CG   C Y N 340 
PHE CD1  C Y N 341 
PHE CD2  C Y N 342 
PHE CE1  C Y N 343 
PHE CE2  C Y N 344 
PHE CZ   C Y N 345 
PHE OXT  O N N 346 
PHE H    H N N 347 
PHE H2   H N N 348 
PHE HA   H N N 349 
PHE HB2  H N N 350 
PHE HB3  H N N 351 
PHE HD1  H N N 352 
PHE HD2  H N N 353 
PHE HE1  H N N 354 
PHE HE2  H N N 355 
PHE HZ   H N N 356 
PHE HXT  H N N 357 
PRO N    N N N 358 
PRO CA   C N S 359 
PRO C    C N N 360 
PRO O    O N N 361 
PRO CB   C N N 362 
PRO CG   C N N 363 
PRO CD   C N N 364 
PRO OXT  O N N 365 
PRO H    H N N 366 
PRO HA   H N N 367 
PRO HB2  H N N 368 
PRO HB3  H N N 369 
PRO HG2  H N N 370 
PRO HG3  H N N 371 
PRO HD2  H N N 372 
PRO HD3  H N N 373 
PRO HXT  H N N 374 
SER N    N N N 375 
SER CA   C N S 376 
SER C    C N N 377 
SER O    O N N 378 
SER CB   C N N 379 
SER OG   O N N 380 
SER OXT  O N N 381 
SER H    H N N 382 
SER H2   H N N 383 
SER HA   H N N 384 
SER HB2  H N N 385 
SER HB3  H N N 386 
SER HG   H N N 387 
SER HXT  H N N 388 
THR N    N N N 389 
THR CA   C N S 390 
THR C    C N N 391 
THR O    O N N 392 
THR CB   C N R 393 
THR OG1  O N N 394 
THR CG2  C N N 395 
THR OXT  O N N 396 
THR H    H N N 397 
THR H2   H N N 398 
THR HA   H N N 399 
THR HB   H N N 400 
THR HG1  H N N 401 
THR HG21 H N N 402 
THR HG22 H N N 403 
THR HG23 H N N 404 
THR HXT  H N N 405 
TRP N    N N N 406 
TRP CA   C N S 407 
TRP C    C N N 408 
TRP O    O N N 409 
TRP CB   C N N 410 
TRP CG   C Y N 411 
TRP CD1  C Y N 412 
TRP CD2  C Y N 413 
TRP NE1  N Y N 414 
TRP CE2  C Y N 415 
TRP CE3  C Y N 416 
TRP CZ2  C Y N 417 
TRP CZ3  C Y N 418 
TRP CH2  C Y N 419 
TRP OXT  O N N 420 
TRP H    H N N 421 
TRP H2   H N N 422 
TRP HA   H N N 423 
TRP HB2  H N N 424 
TRP HB3  H N N 425 
TRP HD1  H N N 426 
TRP HE1  H N N 427 
TRP HE3  H N N 428 
TRP HZ2  H N N 429 
TRP HZ3  H N N 430 
TRP HH2  H N N 431 
TRP HXT  H N N 432 
TYR N    N N N 433 
TYR CA   C N S 434 
TYR C    C N N 435 
TYR O    O N N 436 
TYR CB   C N N 437 
TYR CG   C Y N 438 
TYR CD1  C Y N 439 
TYR CD2  C Y N 440 
TYR CE1  C Y N 441 
TYR CE2  C Y N 442 
TYR CZ   C Y N 443 
TYR OH   O N N 444 
TYR OXT  O N N 445 
TYR H    H N N 446 
TYR H2   H N N 447 
TYR HA   H N N 448 
TYR HB2  H N N 449 
TYR HB3  H N N 450 
TYR HD1  H N N 451 
TYR HD2  H N N 452 
TYR HE1  H N N 453 
TYR HE2  H N N 454 
TYR HH   H N N 455 
TYR HXT  H N N 456 
VAL N    N N N 457 
VAL CA   C N S 458 
VAL C    C N N 459 
VAL O    O N N 460 
VAL CB   C N N 461 
VAL CG1  C N N 462 
VAL CG2  C N N 463 
VAL OXT  O N N 464 
VAL H    H N N 465 
VAL H2   H N N 466 
VAL HA   H N N 467 
VAL HB   H N N 468 
VAL HG11 H N N 469 
VAL HG12 H N N 470 
VAL HG13 H N N 471 
VAL HG21 H N N 472 
VAL HG22 H N N 473 
VAL HG23 H N N 474 
VAL HXT  H N N 475 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
AG7 C01 C02  sing N N 1   
AG7 C01 O03  doub N N 2   
AG7 C01 C57  sing N N 3   
AG7 C02 C04  sing N N 4   
AG7 C02 H2   sing N N 5   
AG7 C02 H3   sing N N 6   
AG7 C04 C05  sing N N 7   
AG7 C04 C47  sing N N 8   
AG7 C04 H27  sing N N 9   
AG7 C05 C06  sing N N 10  
AG7 C05 H28  sing N N 11  
AG7 C05 H29  sing N N 12  
AG7 C06 C07  doub Y N 13  
AG7 C06 C11  sing Y N 14  
AG7 C07 C08  sing Y N 15  
AG7 C07 H30  sing N N 16  
AG7 C08 C09  doub Y N 17  
AG7 C08 H31  sing N N 18  
AG7 C09 C10  sing Y N 19  
AG7 C09 F1   sing N N 20  
AG7 C10 C11  doub Y N 21  
AG7 C10 H33  sing N N 22  
AG7 C11 H34  sing N N 23  
AG7 N12 C13  sing N N 24  
AG7 N12 C47  sing N N 25  
AG7 N12 H49  sing N N 26  
AG7 C13 C14  sing N N 27  
AG7 C13 C19  sing N N 28  
AG7 C13 H91  sing N N 29  
AG7 C14 C15  sing N N 30  
AG7 C14 H35  sing N N 31  
AG7 C14 H36  sing N N 32  
AG7 C15 C16  sing N N 33  
AG7 C15 C84  sing N N 34  
AG7 C15 H94  sing N N 35  
AG7 C16 N17  sing N N 36  
AG7 C16 O18  doub N N 37  
AG7 N17 C83  sing N N 38  
AG7 N17 H39  sing N N 39  
AG7 C19 C20  sing N N 40  
AG7 C19 H191 sing N N 41  
AG7 C19 H192 sing N N 42  
AG7 C20 C21  sing N N 43  
AG7 C20 H41  sing N N 44  
AG7 C20 H42  sing N N 45  
AG7 C21 O22  sing N N 46  
AG7 C21 O23  doub N N 47  
AG7 O22 C50  sing N N 48  
AG7 C47 O48  doub N N 49  
AG7 C50 C53  sing N N 50  
AG7 C50 H51  sing N N 51  
AG7 C50 H52  sing N N 52  
AG7 C53 H53  sing N N 53  
AG7 C53 H54  sing N N 54  
AG7 C53 H56  sing N N 55  
AG7 C57 N58  sing N N 56  
AG7 C57 C78  sing N N 57  
AG7 C57 H77  sing N N 58  
AG7 N58 C59  sing N N 59  
AG7 N58 H61  sing N N 60  
AG7 C59 O60  doub N N 61  
AG7 C59 C1   sing N N 62  
AG7 C78 C81  sing N N 63  
AG7 C78 C82  sing N N 64  
AG7 C78 H79  sing N N 65  
AG7 C81 H82  sing N N 66  
AG7 C81 H84  sing N N 67  
AG7 C81 H85  sing N N 68  
AG7 C82 H86  sing N N 69  
AG7 C82 H87  sing N N 70  
AG7 C82 H88  sing N N 71  
AG7 C83 C84  sing N N 72  
AG7 C83 H89  sing N N 73  
AG7 C83 H90  sing N N 74  
AG7 C84 H92  sing N N 75  
AG7 C84 H93  sing N N 76  
AG7 C1  C2   sing Y N 77  
AG7 C1  N5   doub Y N 78  
AG7 C2  C3   doub Y N 79  
AG7 C2  H8   sing N N 80  
AG7 C3  O4   sing Y N 81  
AG7 C3  C4   sing N N 82  
AG7 O4  N5   sing Y N 83  
AG7 C4  H5   sing N N 84  
AG7 C4  H6   sing N N 85  
AG7 C4  H7   sing N N 86  
ALA N   CA   sing N N 87  
ALA N   H    sing N N 88  
ALA N   H2   sing N N 89  
ALA CA  C    sing N N 90  
ALA CA  CB   sing N N 91  
ALA CA  HA   sing N N 92  
ALA C   O    doub N N 93  
ALA C   OXT  sing N N 94  
ALA CB  HB1  sing N N 95  
ALA CB  HB2  sing N N 96  
ALA CB  HB3  sing N N 97  
ALA OXT HXT  sing N N 98  
ARG N   CA   sing N N 99  
ARG N   H    sing N N 100 
ARG N   H2   sing N N 101 
ARG CA  C    sing N N 102 
ARG CA  CB   sing N N 103 
ARG CA  HA   sing N N 104 
ARG C   O    doub N N 105 
ARG C   OXT  sing N N 106 
ARG CB  CG   sing N N 107 
ARG CB  HB2  sing N N 108 
ARG CB  HB3  sing N N 109 
ARG CG  CD   sing N N 110 
ARG CG  HG2  sing N N 111 
ARG CG  HG3  sing N N 112 
ARG CD  NE   sing N N 113 
ARG CD  HD2  sing N N 114 
ARG CD  HD3  sing N N 115 
ARG NE  CZ   sing N N 116 
ARG NE  HE   sing N N 117 
ARG CZ  NH1  sing N N 118 
ARG CZ  NH2  doub N N 119 
ARG NH1 HH11 sing N N 120 
ARG NH1 HH12 sing N N 121 
ARG NH2 HH21 sing N N 122 
ARG NH2 HH22 sing N N 123 
ARG OXT HXT  sing N N 124 
ASN N   CA   sing N N 125 
ASN N   H    sing N N 126 
ASN N   H2   sing N N 127 
ASN CA  C    sing N N 128 
ASN CA  CB   sing N N 129 
ASN CA  HA   sing N N 130 
ASN C   O    doub N N 131 
ASN C   OXT  sing N N 132 
ASN CB  CG   sing N N 133 
ASN CB  HB2  sing N N 134 
ASN CB  HB3  sing N N 135 
ASN CG  OD1  doub N N 136 
ASN CG  ND2  sing N N 137 
ASN ND2 HD21 sing N N 138 
ASN ND2 HD22 sing N N 139 
ASN OXT HXT  sing N N 140 
ASP N   CA   sing N N 141 
ASP N   H    sing N N 142 
ASP N   H2   sing N N 143 
ASP CA  C    sing N N 144 
ASP CA  CB   sing N N 145 
ASP CA  HA   sing N N 146 
ASP C   O    doub N N 147 
ASP C   OXT  sing N N 148 
ASP CB  CG   sing N N 149 
ASP CB  HB2  sing N N 150 
ASP CB  HB3  sing N N 151 
ASP CG  OD1  doub N N 152 
ASP CG  OD2  sing N N 153 
ASP OD2 HD2  sing N N 154 
ASP OXT HXT  sing N N 155 
CYS N   CA   sing N N 156 
CYS N   H    sing N N 157 
CYS N   H2   sing N N 158 
CYS CA  C    sing N N 159 
CYS CA  CB   sing N N 160 
CYS CA  HA   sing N N 161 
CYS C   O    doub N N 162 
CYS C   OXT  sing N N 163 
CYS CB  SG   sing N N 164 
CYS CB  HB2  sing N N 165 
CYS CB  HB3  sing N N 166 
CYS SG  HG   sing N N 167 
CYS OXT HXT  sing N N 168 
GLN N   CA   sing N N 169 
GLN N   H    sing N N 170 
GLN N   H2   sing N N 171 
GLN CA  C    sing N N 172 
GLN CA  CB   sing N N 173 
GLN CA  HA   sing N N 174 
GLN C   O    doub N N 175 
GLN C   OXT  sing N N 176 
GLN CB  CG   sing N N 177 
GLN CB  HB2  sing N N 178 
GLN CB  HB3  sing N N 179 
GLN CG  CD   sing N N 180 
GLN CG  HG2  sing N N 181 
GLN CG  HG3  sing N N 182 
GLN CD  OE1  doub N N 183 
GLN CD  NE2  sing N N 184 
GLN NE2 HE21 sing N N 185 
GLN NE2 HE22 sing N N 186 
GLN OXT HXT  sing N N 187 
GLU N   CA   sing N N 188 
GLU N   H    sing N N 189 
GLU N   H2   sing N N 190 
GLU CA  C    sing N N 191 
GLU CA  CB   sing N N 192 
GLU CA  HA   sing N N 193 
GLU C   O    doub N N 194 
GLU C   OXT  sing N N 195 
GLU CB  CG   sing N N 196 
GLU CB  HB2  sing N N 197 
GLU CB  HB3  sing N N 198 
GLU CG  CD   sing N N 199 
GLU CG  HG2  sing N N 200 
GLU CG  HG3  sing N N 201 
GLU CD  OE1  doub N N 202 
GLU CD  OE2  sing N N 203 
GLU OE2 HE2  sing N N 204 
GLU OXT HXT  sing N N 205 
GLY N   CA   sing N N 206 
GLY N   H    sing N N 207 
GLY N   H2   sing N N 208 
GLY CA  C    sing N N 209 
GLY CA  HA2  sing N N 210 
GLY CA  HA3  sing N N 211 
GLY C   O    doub N N 212 
GLY C   OXT  sing N N 213 
GLY OXT HXT  sing N N 214 
HIS N   CA   sing N N 215 
HIS N   H    sing N N 216 
HIS N   H2   sing N N 217 
HIS CA  C    sing N N 218 
HIS CA  CB   sing N N 219 
HIS CA  HA   sing N N 220 
HIS C   O    doub N N 221 
HIS C   OXT  sing N N 222 
HIS CB  CG   sing N N 223 
HIS CB  HB2  sing N N 224 
HIS CB  HB3  sing N N 225 
HIS CG  ND1  sing Y N 226 
HIS CG  CD2  doub Y N 227 
HIS ND1 CE1  doub Y N 228 
HIS ND1 HD1  sing N N 229 
HIS CD2 NE2  sing Y N 230 
HIS CD2 HD2  sing N N 231 
HIS CE1 NE2  sing Y N 232 
HIS CE1 HE1  sing N N 233 
HIS NE2 HE2  sing N N 234 
HIS OXT HXT  sing N N 235 
HOH O   H1   sing N N 236 
HOH O   H2   sing N N 237 
ILE N   CA   sing N N 238 
ILE N   H    sing N N 239 
ILE N   H2   sing N N 240 
ILE CA  C    sing N N 241 
ILE CA  CB   sing N N 242 
ILE CA  HA   sing N N 243 
ILE C   O    doub N N 244 
ILE C   OXT  sing N N 245 
ILE CB  CG1  sing N N 246 
ILE CB  CG2  sing N N 247 
ILE CB  HB   sing N N 248 
ILE CG1 CD1  sing N N 249 
ILE CG1 HG12 sing N N 250 
ILE CG1 HG13 sing N N 251 
ILE CG2 HG21 sing N N 252 
ILE CG2 HG22 sing N N 253 
ILE CG2 HG23 sing N N 254 
ILE CD1 HD11 sing N N 255 
ILE CD1 HD12 sing N N 256 
ILE CD1 HD13 sing N N 257 
ILE OXT HXT  sing N N 258 
LEU N   CA   sing N N 259 
LEU N   H    sing N N 260 
LEU N   H2   sing N N 261 
LEU CA  C    sing N N 262 
LEU CA  CB   sing N N 263 
LEU CA  HA   sing N N 264 
LEU C   O    doub N N 265 
LEU C   OXT  sing N N 266 
LEU CB  CG   sing N N 267 
LEU CB  HB2  sing N N 268 
LEU CB  HB3  sing N N 269 
LEU CG  CD1  sing N N 270 
LEU CG  CD2  sing N N 271 
LEU CG  HG   sing N N 272 
LEU CD1 HD11 sing N N 273 
LEU CD1 HD12 sing N N 274 
LEU CD1 HD13 sing N N 275 
LEU CD2 HD21 sing N N 276 
LEU CD2 HD22 sing N N 277 
LEU CD2 HD23 sing N N 278 
LEU OXT HXT  sing N N 279 
LYS N   CA   sing N N 280 
LYS N   H    sing N N 281 
LYS N   H2   sing N N 282 
LYS CA  C    sing N N 283 
LYS CA  CB   sing N N 284 
LYS CA  HA   sing N N 285 
LYS C   O    doub N N 286 
LYS C   OXT  sing N N 287 
LYS CB  CG   sing N N 288 
LYS CB  HB2  sing N N 289 
LYS CB  HB3  sing N N 290 
LYS CG  CD   sing N N 291 
LYS CG  HG2  sing N N 292 
LYS CG  HG3  sing N N 293 
LYS CD  CE   sing N N 294 
LYS CD  HD2  sing N N 295 
LYS CD  HD3  sing N N 296 
LYS CE  NZ   sing N N 297 
LYS CE  HE2  sing N N 298 
LYS CE  HE3  sing N N 299 
LYS NZ  HZ1  sing N N 300 
LYS NZ  HZ2  sing N N 301 
LYS NZ  HZ3  sing N N 302 
LYS OXT HXT  sing N N 303 
MET N   CA   sing N N 304 
MET N   H    sing N N 305 
MET N   H2   sing N N 306 
MET CA  C    sing N N 307 
MET CA  CB   sing N N 308 
MET CA  HA   sing N N 309 
MET C   O    doub N N 310 
MET C   OXT  sing N N 311 
MET CB  CG   sing N N 312 
MET CB  HB2  sing N N 313 
MET CB  HB3  sing N N 314 
MET CG  SD   sing N N 315 
MET CG  HG2  sing N N 316 
MET CG  HG3  sing N N 317 
MET SD  CE   sing N N 318 
MET CE  HE1  sing N N 319 
MET CE  HE2  sing N N 320 
MET CE  HE3  sing N N 321 
MET OXT HXT  sing N N 322 
PHE N   CA   sing N N 323 
PHE N   H    sing N N 324 
PHE N   H2   sing N N 325 
PHE CA  C    sing N N 326 
PHE CA  CB   sing N N 327 
PHE CA  HA   sing N N 328 
PHE C   O    doub N N 329 
PHE C   OXT  sing N N 330 
PHE CB  CG   sing N N 331 
PHE CB  HB2  sing N N 332 
PHE CB  HB3  sing N N 333 
PHE CG  CD1  doub Y N 334 
PHE CG  CD2  sing Y N 335 
PHE CD1 CE1  sing Y N 336 
PHE CD1 HD1  sing N N 337 
PHE CD2 CE2  doub Y N 338 
PHE CD2 HD2  sing N N 339 
PHE CE1 CZ   doub Y N 340 
PHE CE1 HE1  sing N N 341 
PHE CE2 CZ   sing Y N 342 
PHE CE2 HE2  sing N N 343 
PHE CZ  HZ   sing N N 344 
PHE OXT HXT  sing N N 345 
PRO N   CA   sing N N 346 
PRO N   CD   sing N N 347 
PRO N   H    sing N N 348 
PRO CA  C    sing N N 349 
PRO CA  CB   sing N N 350 
PRO CA  HA   sing N N 351 
PRO C   O    doub N N 352 
PRO C   OXT  sing N N 353 
PRO CB  CG   sing N N 354 
PRO CB  HB2  sing N N 355 
PRO CB  HB3  sing N N 356 
PRO CG  CD   sing N N 357 
PRO CG  HG2  sing N N 358 
PRO CG  HG3  sing N N 359 
PRO CD  HD2  sing N N 360 
PRO CD  HD3  sing N N 361 
PRO OXT HXT  sing N N 362 
SER N   CA   sing N N 363 
SER N   H    sing N N 364 
SER N   H2   sing N N 365 
SER CA  C    sing N N 366 
SER CA  CB   sing N N 367 
SER CA  HA   sing N N 368 
SER C   O    doub N N 369 
SER C   OXT  sing N N 370 
SER CB  OG   sing N N 371 
SER CB  HB2  sing N N 372 
SER CB  HB3  sing N N 373 
SER OG  HG   sing N N 374 
SER OXT HXT  sing N N 375 
THR N   CA   sing N N 376 
THR N   H    sing N N 377 
THR N   H2   sing N N 378 
THR CA  C    sing N N 379 
THR CA  CB   sing N N 380 
THR CA  HA   sing N N 381 
THR C   O    doub N N 382 
THR C   OXT  sing N N 383 
THR CB  OG1  sing N N 384 
THR CB  CG2  sing N N 385 
THR CB  HB   sing N N 386 
THR OG1 HG1  sing N N 387 
THR CG2 HG21 sing N N 388 
THR CG2 HG22 sing N N 389 
THR CG2 HG23 sing N N 390 
THR OXT HXT  sing N N 391 
TRP N   CA   sing N N 392 
TRP N   H    sing N N 393 
TRP N   H2   sing N N 394 
TRP CA  C    sing N N 395 
TRP CA  CB   sing N N 396 
TRP CA  HA   sing N N 397 
TRP C   O    doub N N 398 
TRP C   OXT  sing N N 399 
TRP CB  CG   sing N N 400 
TRP CB  HB2  sing N N 401 
TRP CB  HB3  sing N N 402 
TRP CG  CD1  doub Y N 403 
TRP CG  CD2  sing Y N 404 
TRP CD1 NE1  sing Y N 405 
TRP CD1 HD1  sing N N 406 
TRP CD2 CE2  doub Y N 407 
TRP CD2 CE3  sing Y N 408 
TRP NE1 CE2  sing Y N 409 
TRP NE1 HE1  sing N N 410 
TRP CE2 CZ2  sing Y N 411 
TRP CE3 CZ3  doub Y N 412 
TRP CE3 HE3  sing N N 413 
TRP CZ2 CH2  doub Y N 414 
TRP CZ2 HZ2  sing N N 415 
TRP CZ3 CH2  sing Y N 416 
TRP CZ3 HZ3  sing N N 417 
TRP CH2 HH2  sing N N 418 
TRP OXT HXT  sing N N 419 
TYR N   CA   sing N N 420 
TYR N   H    sing N N 421 
TYR N   H2   sing N N 422 
TYR CA  C    sing N N 423 
TYR CA  CB   sing N N 424 
TYR CA  HA   sing N N 425 
TYR C   O    doub N N 426 
TYR C   OXT  sing N N 427 
TYR CB  CG   sing N N 428 
TYR CB  HB2  sing N N 429 
TYR CB  HB3  sing N N 430 
TYR CG  CD1  doub Y N 431 
TYR CG  CD2  sing Y N 432 
TYR CD1 CE1  sing Y N 433 
TYR CD1 HD1  sing N N 434 
TYR CD2 CE2  doub Y N 435 
TYR CD2 HD2  sing N N 436 
TYR CE1 CZ   doub Y N 437 
TYR CE1 HE1  sing N N 438 
TYR CE2 CZ   sing Y N 439 
TYR CE2 HE2  sing N N 440 
TYR CZ  OH   sing N N 441 
TYR OH  HH   sing N N 442 
TYR OXT HXT  sing N N 443 
VAL N   CA   sing N N 444 
VAL N   H    sing N N 445 
VAL N   H2   sing N N 446 
VAL CA  C    sing N N 447 
VAL CA  CB   sing N N 448 
VAL CA  HA   sing N N 449 
VAL C   O    doub N N 450 
VAL C   OXT  sing N N 451 
VAL CB  CG1  sing N N 452 
VAL CB  CG2  sing N N 453 
VAL CB  HB   sing N N 454 
VAL CG1 HG11 sing N N 455 
VAL CG1 HG12 sing N N 456 
VAL CG1 HG13 sing N N 457 
VAL CG2 HG21 sing N N 458 
VAL CG2 HG22 sing N N 459 
VAL CG2 HG23 sing N N 460 
VAL OXT HXT  sing N N 461 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'P01 AI057788' 1 
'Robert A. Welch Foundation'                                                                      'United States' Q-1279         2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6NIR 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9D9T 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010168 
_atom_sites.fract_transf_matrix[1][2]   0.005870 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011741 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.021608 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356  2.42580  ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 8.95735  ?        ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345  0.48472  ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
I ? ? 40.26819 12.56501 ? ? 1.42647  27.02115 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032  2.96436  ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882  3.47563  ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732  6.39887  ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . SER A 1 6   ? 15.94500 22.81300 2.43100   1.000 56.11000  ? 4   SER A N    1 
ATOM   2    C CA   . SER A 1 6   ? 16.42600 22.02400 3.56600   1.000 56.22000  ? 4   SER A CA   1 
ATOM   3    C C    . SER A 1 6   ? 17.88600 22.36000 3.84600   1.000 56.58000  ? 4   SER A C    1 
ATOM   4    O O    . SER A 1 6   ? 18.19200 23.16600 4.72800   1.000 54.29000  ? 4   SER A O    1 
ATOM   5    C CB   . SER A 1 6   ? 16.26300 20.52600 3.29400   1.000 80.65000  ? 4   SER A CB   1 
ATOM   6    O OG   . SER A 1 6   ? 16.85300 20.14000 2.06100   1.000 74.37000  ? 4   SER A OG   1 
ATOM   7    H HA   . SER A 1 6   ? 15.90700 22.24800 4.35300   1.000 67.32000  ? 4   SER A HA   1 
ATOM   8    H HB2  . SER A 1 6   ? 16.68800 20.03100 4.01200   1.000 96.63000  ? 4   SER A HB2  1 
ATOM   9    H HB3  . SER A 1 6   ? 15.31700 20.31500 3.26600   1.000 96.63000  ? 4   SER A HB3  1 
ATOM   10   H HG   . SER A 1 6   ? 16.49100 20.55400 1.42700   1.000 89.09000  ? 4   SER A HG   1 
ATOM   11   N N    . ILE A 1 7   ? 18.78600 21.72800 3.08800   1.000 53.39000  ? 5   ILE A N    1 
ATOM   12   C CA   . ILE A 1 7   ? 20.20000 22.06800 3.17500   1.000 41.25000  ? 5   ILE A CA   1 
ATOM   13   C C    . ILE A 1 7   ? 20.44500 23.43300 2.54800   1.000 43.82000  ? 5   ILE A C    1 
ATOM   14   O O    . ILE A 1 7   ? 21.34900 24.16900 2.95900   1.000 39.50000  ? 5   ILE A O    1 
ATOM   15   C CB   . ILE A 1 7   ? 21.05400 20.98700 2.49000   1.000 51.59000  ? 5   ILE A CB   1 
ATOM   16   C CG1  . ILE A 1 7   ? 20.66100 19.57900 2.96100   1.000 69.09000  ? 5   ILE A CG1  1 
ATOM   17   C CG2  . ILE A 1 7   ? 22.53300 21.22600 2.75100   1.000 54.26000  ? 5   ILE A CG2  1 
ATOM   18   C CD1  . ILE A 1 7   ? 20.29200 19.46500 4.44300   1.000 71.96000  ? 5   ILE A CD1  1 
ATOM   19   H H    . ILE A 1 7   ? 18.60400 21.10700 2.52200   1.000 63.92000  ? 5   ILE A H    1 
ATOM   20   H HA   . ILE A 1 7   ? 20.46100 22.11800 4.10800   1.000 49.35000  ? 5   ILE A HA   1 
ATOM   21   H HB   . ILE A 1 7   ? 20.90300 21.04100 1.53400   1.000 61.76000  ? 5   ILE A HB   1 
ATOM   22   H HG12 . ILE A 1 7   ? 19.89300 19.28700 2.44600   1.000 82.76000  ? 5   ILE A HG12 1 
ATOM   23   H HG13 . ILE A 1 7   ? 21.40600 18.98000 2.79900   1.000 82.76000  ? 5   ILE A HG13 1 
ATOM   24   H HG21 . ILE A 1 7   ? 23.04400 20.50400 2.35300   1.000 64.96000  ? 5   ILE A HG21 1 
ATOM   25   H HG22 . ILE A 1 7   ? 22.79400 22.07200 2.35500   1.000 64.96000  ? 5   ILE A HG22 1 
ATOM   26   H HG23 . ILE A 1 7   ? 22.68400 21.24900 3.70900   1.000 64.96000  ? 5   ILE A HG23 1 
ATOM   27   H HD11 . ILE A 1 7   ? 20.33400 18.53200 4.70400   1.000 86.21000  ? 5   ILE A HD11 1 
ATOM   28   H HD12 . ILE A 1 7   ? 20.92200 19.98400 4.96600   1.000 86.21000  ? 5   ILE A HD12 1 
ATOM   29   H HD13 . ILE A 1 7   ? 19.39400 19.80300 4.57700   1.000 86.21000  ? 5   ILE A HD13 1 
ATOM   30   N N    . TRP A 1 8   ? 19.64400 23.79100 1.54800   1.000 37.71000  ? 6   TRP A N    1 
ATOM   31   C CA   . TRP A 1 8   ? 19.87800 25.03600 0.82700   1.000 37.47000  ? 6   TRP A CA   1 
ATOM   32   C C    . TRP A 1 8   ? 19.69400 26.24800 1.72400   1.000 40.13000  ? 6   TRP A C    1 
ATOM   33   O O    . TRP A 1 8   ? 20.36400 27.26800 1.52300   1.000 35.39000  ? 6   TRP A O    1 
ATOM   34   C CB   . TRP A 1 8   ? 18.95600 25.09500 -0.39000  1.000 43.58000  ? 6   TRP A CB   1 
ATOM   35   C CG   . TRP A 1 8   ? 19.34500 24.10200 -1.45300  1.000 39.79000  ? 6   TRP A CG   1 
ATOM   36   C CD1  . TRP A 1 8   ? 18.75200 22.90100 -1.71400  1.000 39.92000  ? 6   TRP A CD1  1 
ATOM   37   C CD2  . TRP A 1 8   ? 20.42200 24.23200 -2.38600  1.000 40.23000  ? 6   TRP A CD2  1 
ATOM   38   N NE1  . TRP A 1 8   ? 19.39200 22.27500 -2.75900  1.000 41.45000  ? 6   TRP A NE1  1 
ATOM   39   C CE2  . TRP A 1 8   ? 20.42200 23.07200 -3.18800  1.000 43.13000  ? 6   TRP A CE2  1 
ATOM   40   C CE3  . TRP A 1 8   ? 21.38600 25.21900 -2.62200  1.000 39.01000  ? 6   TRP A CE3  1 
ATOM   41   C CZ2  . TRP A 1 8   ? 21.34600 22.87400 -4.20800  1.000 46.03000  ? 6   TRP A CZ2  1 
ATOM   42   C CZ3  . TRP A 1 8   ? 22.30100 25.02000 -3.63500  1.000 48.67000  ? 6   TRP A CZ3  1 
ATOM   43   C CH2  . TRP A 1 8   ? 22.27600 23.85700 -4.41700  1.000 44.90000  ? 6   TRP A CH2  1 
ATOM   44   H H    . TRP A 1 8   ? 18.96800 23.33700 1.27100   1.000 45.10000  ? 6   TRP A H    1 
ATOM   45   H HA   . TRP A 1 8   ? 20.79300 25.04300 0.50500   1.000 44.82000  ? 6   TRP A HA   1 
ATOM   46   H HB2  . TRP A 1 8   ? 18.04900 24.89600 -0.11000  1.000 52.14000  ? 6   TRP A HB2  1 
ATOM   47   H HB3  . TRP A 1 8   ? 18.99800 25.98300 -0.77700  1.000 52.14000  ? 6   TRP A HB3  1 
ATOM   48   H HD1  . TRP A 1 8   ? 18.02100 22.55700 -1.25500  1.000 47.75000  ? 6   TRP A HD1  1 
ATOM   49   H HE1  . TRP A 1 8   ? 19.18200 21.51000 -3.08900  1.000 49.60000  ? 6   TRP A HE1  1 
ATOM   50   H HE3  . TRP A 1 8   ? 21.40800 25.99400 -2.10700  1.000 46.66000  ? 6   TRP A HE3  1 
ATOM   51   H HZ2  . TRP A 1 8   ? 21.33200 22.10300 -4.72900  1.000 55.09000  ? 6   TRP A HZ2  1 
ATOM   52   H HZ3  . TRP A 1 8   ? 22.94600 25.66800 -3.80200  1.000 58.25000  ? 6   TRP A HZ3  1 
ATOM   53   H HH2  . TRP A 1 8   ? 22.90600 23.75000 -5.09300  1.000 53.73000  ? 6   TRP A HH2  1 
ATOM   54   N N    . SER A 1 9   ? 18.82000 26.15400 2.72700   1.000 32.93000  ? 7   SER A N    1 
ATOM   55   C CA   . SER A 1 9   ? 18.59600 27.28400 3.61600   1.000 35.63000  ? 7   SER A CA   1 
ATOM   56   C C    . SER A 1 9   ? 19.83600 27.62100 4.42500   1.000 44.08000  ? 7   SER A C    1 
ATOM   57   O O    . SER A 1 9   ? 19.92200 28.72900 4.97200   1.000 39.07000  ? 7   SER A O    1 
ATOM   58   C CB   . SER A 1 9   ? 17.43000 26.99400 4.55900   1.000 37.21000  ? 7   SER A CB   1 
ATOM   59   O OG   . SER A 1 9   ? 17.72100 25.89300 5.39700   1.000 45.05000  ? 7   SER A OG   1 
ATOM   60   H H    . SER A 1 9   ? 18.35200 25.45600 2.90800   1.000 39.36000  ? 7   SER A H    1 
ATOM   61   H HA   . SER A 1 9   ? 18.36500 28.06300 3.08400   1.000 42.61000  ? 7   SER A HA   1 
ATOM   62   H HB2  . SER A 1 9   ? 17.26700 27.77600 5.11100   1.000 44.51000  ? 7   SER A HB2  1 
ATOM   63   H HB3  . SER A 1 9   ? 16.64100 26.79100 4.03300   1.000 44.51000  ? 7   SER A HB3  1 
ATOM   64   H HG   . SER A 1 9   ? 17.86400 25.20800 4.93200   1.000 53.91000  ? 7   SER A HG   1 
ATOM   65   N N    . ARG A 1 10  ? 20.79000 26.68800 4.50700   1.000 34.55000  ? 8   ARG A N    1 
ATOM   66   C CA   . ARG A 1 10  ? 22.02100 26.87900 5.25600   1.000 42.25000  ? 8   ARG A CA   1 
ATOM   67   C C    . ARG A 1 10  ? 23.08000 27.64000 4.47300   1.000 40.43000  ? 8   ARG A C    1 
ATOM   68   O O    . ARG A 1 10  ? 24.09500 28.03200 5.06200   1.000 36.51000  ? 8   ARG A O    1 
ATOM   69   C CB   . ARG A 1 10  ? 22.57700 25.51500 5.69000   1.000 35.05000  ? 8   ARG A CB   1 
ATOM   70   C CG   . ARG A 1 10  ? 21.62800 24.73300 6.60500   1.000 49.54000  ? 8   ARG A CG   1 
ATOM   71   C CD   . ARG A 1 10  ? 21.92700 23.23000 6.63800   1.000 49.84000  ? 8   ARG A CD   1 
ATOM   72   N NE   . ARG A 1 10  ? 22.91100 22.91400 7.66500   1.000 52.38000  ? 8   ARG A NE   1 
ATOM   73   C CZ   . ARG A 1 10  ? 22.78900 21.95400 8.57300   1.000 47.74000  ? 8   ARG A CZ   1 
ATOM   74   N NH1  . ARG A 1 10  ? 21.73600 21.15300 8.60300   1.000 48.22000  ? 8   ARG A NH1  1 
ATOM   75   N NH2  . ARG A 1 10  ? 23.75400 21.79700 9.47500   1.000 52.03000  ? 8   ARG A NH2  1 
ATOM   76   H H    . ARG A 1 10  ? 20.74000 25.91800 4.12600   1.000 41.31000  ? 8   ARG A H    1 
ATOM   77   H HA   . ARG A 1 10  ? 21.82300 27.38800 6.05800   1.000 50.55000  ? 8   ARG A HA   1 
ATOM   78   H HB2  . ARG A 1 10  ? 22.74000 24.97800 4.89900   1.000 41.91000  ? 8   ARG A HB2  1 
ATOM   79   H HB3  . ARG A 1 10  ? 23.40800 25.65400 6.17100   1.000 41.91000  ? 8   ARG A HB3  1 
ATOM   80   H HG2  . ARG A 1 10  ? 21.71200 25.07400 7.50900   1.000 59.30000  ? 8   ARG A HG2  1 
ATOM   81   H HG3  . ARG A 1 10  ? 20.71700 24.84800 6.29200   1.000 59.30000  ? 8   ARG A HG3  1 
ATOM   82   H HD2  . ARG A 1 10  ? 21.10400 22.75500 6.82100   1.000 59.66000  ? 8   ARG A HD2  1 
ATOM   83   H HD3  . ARG A 1 10  ? 22.28700 22.95500 5.78000   1.000 59.66000  ? 8   ARG A HD3  1 
ATOM   84   H HE   . ARG A 1 10  ? 23.62800 23.38700 7.68500   1.000 62.71000  ? 8   ARG A HE   1 
ATOM   85   H HH11 . ARG A 1 10  ? 21.10400 21.24000 8.03000   1.000 57.72000  ? 8   ARG A HH11 1 
ATOM   86   H HH12 . ARG A 1 10  ? 21.68600 20.53900 9.20300   1.000 57.72000  ? 8   ARG A HH12 1 
ATOM   87   H HH21 . ARG A 1 10  ? 24.44200 22.31200 9.46100   1.000 62.29000  ? 8   ARG A HH21 1 
ATOM   88   H HH22 . ARG A 1 10  ? 23.69100 21.17900 10.06900  1.000 62.29000  ? 8   ARG A HH22 1 
ATOM   89   N N    . ILE A 1 11  ? 22.87400 27.85100 3.17500   1.000 36.31000  ? 9   ILE A N    1 
ATOM   90   C CA   . ILE A 1 11  ? 23.78400 28.62800 2.34100   1.000 34.65000  ? 9   ILE A CA   1 
ATOM   91   C C    . ILE A 1 11  ? 23.23300 30.04100 2.27100   1.000 39.14000  ? 9   ILE A C    1 
ATOM   92   O O    . ILE A 1 11  ? 22.08200 30.24500 1.86100   1.000 39.64000  ? 9   ILE A O    1 
ATOM   93   C CB   . ILE A 1 11  ? 23.92300 28.02200 0.94000   1.000 32.73000  ? 9   ILE A CB   1 
ATOM   94   C CG1  . ILE A 1 11  ? 24.52000 26.61500 1.02600   1.000 42.58000  ? 9   ILE A CG1  1 
ATOM   95   C CG2  . ILE A 1 11  ? 24.81100 28.90400 0.06000   1.000 40.17000  ? 9   ILE A CG2  1 
ATOM   96   C CD1  . ILE A 1 11  ? 24.04000 25.68500 -0.06700  1.000 44.69000  ? 9   ILE A CD1  1 
ATOM   97   H H    . ILE A 1 11  ? 22.19600 27.54500 2.74300   1.000 43.42000  ? 9   ILE A H    1 
ATOM   98   H HA   . ILE A 1 11  ? 24.66000 28.65700 2.75400   1.000 41.43000  ? 9   ILE A HA   1 
ATOM   99   H HB   . ILE A 1 11  ? 23.04300 27.96200 0.53800   1.000 39.12000  ? 9   ILE A HB   1 
ATOM   100  H HG12 . ILE A 1 11  ? 25.48500 26.68200 0.95400   1.000 50.95000  ? 9   ILE A HG12 1 
ATOM   101  H HG13 . ILE A 1 11  ? 24.28000 26.21900 1.87800   1.000 50.95000  ? 9   ILE A HG13 1 
ATOM   102  H HG21 . ILE A 1 11  ? 25.05600 28.40700 -0.73700  1.000 48.06000  ? 9   ILE A HG21 1 
ATOM   103  H HG22 . ILE A 1 11  ? 24.32200 29.70300 -0.18800  1.000 48.06000  ? 9   ILE A HG22 1 
ATOM   104  H HG23 . ILE A 1 11  ? 25.60900 29.14200 0.55600   1.000 48.06000  ? 9   ILE A HG23 1 
ATOM   105  H HD11 . ILE A 1 11  ? 24.45800 24.81800 0.05200   1.000 53.49000  ? 9   ILE A HD11 1 
ATOM   106  H HD12 . ILE A 1 11  ? 23.07600 25.59900 -0.00700  1.000 53.49000  ? 9   ILE A HD12 1 
ATOM   107  H HD13 . ILE A 1 11  ? 24.28600 26.05600 -0.92800  1.000 53.49000  ? 9   ILE A HD13 1 
ATOM   108  N N    . VAL A 1 12  ? 24.04300 31.02200 2.66700   1.000 32.04000  ? 10  VAL A N    1 
ATOM   109  C CA   . VAL A 1 12  ? 23.56000 32.38700 2.81100   1.000 38.13000  ? 10  VAL A CA   1 
ATOM   110  C C    . VAL A 1 12  ? 24.56800 33.36600 2.22800   1.000 37.21000  ? 10  VAL A C    1 
ATOM   111  O O    . VAL A 1 12  ? 25.77800 33.11900 2.22400   1.000 38.66000  ? 10  VAL A O    1 
ATOM   112  C CB   . VAL A 1 12  ? 23.25700 32.73200 4.29100   1.000 47.18000  ? 10  VAL A CB   1 
ATOM   113  C CG1  . VAL A 1 12  ? 22.53300 31.56900 4.98300   1.000 47.79000  ? 10  VAL A CG1  1 
ATOM   114  C CG2  . VAL A 1 12  ? 24.53600 33.07500 5.03600   1.000 48.81000  ? 10  VAL A CG2  1 
ATOM   115  H H    . VAL A 1 12  ? 24.87500 30.92000 2.85800   1.000 38.31000  ? 10  VAL A H    1 
ATOM   116  H HA   . VAL A 1 12  ? 22.73400 32.48400 2.31200   1.000 45.61000  ? 10  VAL A HA   1 
ATOM   117  H HB   . VAL A 1 12  ? 22.67600 33.50800 4.32200   1.000 56.47000  ? 10  VAL A HB   1 
ATOM   118  H HG11 . VAL A 1 12  ? 22.23600 31.86100 5.85800   1.000 57.20000  ? 10  VAL A HG11 1 
ATOM   119  H HG12 . VAL A 1 12  ? 21.76900 31.30900 4.44400   1.000 57.20000  ? 10  VAL A HG12 1 
ATOM   120  H HG13 . VAL A 1 12  ? 23.14500 30.82200 5.07300   1.000 57.20000  ? 10  VAL A HG13 1 
ATOM   121  H HG21 . VAL A 1 12  ? 24.37600 32.99400 5.98900   1.000 58.42000  ? 10  VAL A HG21 1 
ATOM   122  H HG22 . VAL A 1 12  ? 25.23400 32.45900 4.76500   1.000 58.42000  ? 10  VAL A HG22 1 
ATOM   123  H HG23 . VAL A 1 12  ? 24.79500 33.98500 4.82100   1.000 58.42000  ? 10  VAL A HG23 1 
ATOM   124  N N    . ASN A 1 13  ? 24.04700 34.48500 1.72900   1.000 35.82000  ? 11  ASN A N    1 
ATOM   125  C CA   . ASN A 1 13  ? 24.88100 35.57600 1.24200   1.000 37.48000  ? 11  ASN A CA   1 
ATOM   126  C C    . ASN A 1 13  ? 25.85100 36.02200 2.32500   1.000 40.52000  ? 11  ASN A C    1 
ATOM   127  O O    . ASN A 1 13  ? 25.44500 36.30700 3.45200   1.000 45.63000  ? 11  ASN A O    1 
ATOM   128  C CB   . ASN A 1 13  ? 23.99100 36.74800 0.81800   1.000 48.57000  ? 11  ASN A CB   1 
ATOM   129  C CG   . ASN A 1 13  ? 24.36100 37.29900 -0.53900  1.000 58.56000  ? 11  ASN A CG   1 
ATOM   130  O OD1  . ASN A 1 13  ? 25.41900 37.90700 -0.70600  1.000 62.83000  ? 11  ASN A OD1  1 
ATOM   131  N ND2  . ASN A 1 13  ? 23.48600 37.09600 -1.52100  1.000 64.24000  ? 11  ASN A ND2  1 
ATOM   132  H H    . ASN A 1 13  ? 23.20500 34.63400 1.66300   1.000 42.84000  ? 11  ASN A H    1 
ATOM   133  H HA   . ASN A 1 13  ? 25.39000 35.27800 0.47200   1.000 44.83000  ? 11  ASN A HA   1 
ATOM   134  H HB2  . ASN A 1 13  ? 23.06800 36.45200 0.77900   1.000 58.14000  ? 11  ASN A HB2  1 
ATOM   135  H HB3  . ASN A 1 13  ? 24.08200 37.46300 1.46600   1.000 58.14000  ? 11  ASN A HB3  1 
ATOM   136  H HD21 . ASN A 1 13  ? 22.75700 36.66800 -1.36700  1.000 76.95000  ? 11  ASN A HD21 1 
ATOM   137  H HD22 . ASN A 1 13  ? 23.65100 37.39200 -2.31200  1.000 76.95000  ? 11  ASN A HD22 1 
ATOM   138  N N    . PHE A 1 14  ? 27.13700 36.07900 1.97900   1.000 36.37000  ? 12  PHE A N    1 
ATOM   139  C CA   . PHE A 1 14  ? 28.16900 36.46300 2.94000   1.000 40.32000  ? 12  PHE A CA   1 
ATOM   140  C C    . PHE A 1 14  ? 29.27700 37.19900 2.19900   1.000 43.54000  ? 12  PHE A C    1 
ATOM   141  O O    . PHE A 1 14  ? 30.02600 36.58600 1.43500   1.000 37.46000  ? 12  PHE A O    1 
ATOM   142  C CB   . PHE A 1 14  ? 28.71500 35.23600 3.67000   1.000 45.29000  ? 12  PHE A CB   1 
ATOM   143  C CG   . PHE A 1 14  ? 29.42700 35.55500 4.95000   1.000 42.62000  ? 12  PHE A CG   1 
ATOM   144  C CD1  . PHE A 1 14  ? 28.74800 36.13600 6.00700   1.000 37.97000  ? 12  PHE A CD1  1 
ATOM   145  C CD2  . PHE A 1 14  ? 30.77200 35.27300 5.10100   1.000 36.96000  ? 12  PHE A CD2  1 
ATOM   146  C CE1  . PHE A 1 14  ? 29.39900 36.43500 7.18600   1.000 34.12000  ? 12  PHE A CE1  1 
ATOM   147  C CE2  . PHE A 1 14  ? 31.42800 35.56400 6.27600   1.000 38.88000  ? 12  PHE A CE2  1 
ATOM   148  C CZ   . PHE A 1 14  ? 30.73700 36.15100 7.32000   1.000 41.35000  ? 12  PHE A CZ   1 
ATOM   149  H H    . PHE A 1 14  ? 27.43700 35.89900 1.19300   1.000 43.50000  ? 12  PHE A H    1 
ATOM   150  H HA   . PHE A 1 14  ? 27.78800 37.06800 3.59500   1.000 48.24000  ? 12  PHE A HA   1 
ATOM   151  H HB2  . PHE A 1 14  ? 27.97600 34.64500 3.88200   1.000 54.20000  ? 12  PHE A HB2  1 
ATOM   152  H HB3  . PHE A 1 14  ? 29.34300 34.78000 3.08800   1.000 54.20000  ? 12  PHE A HB3  1 
ATOM   153  H HD1  . PHE A 1 14  ? 27.84300 36.33300 5.92000   1.000 45.42000  ? 12  PHE A HD1  1 
ATOM   154  H HD2  . PHE A 1 14  ? 31.23900 34.88100 4.39900   1.000 44.20000  ? 12  PHE A HD2  1 
ATOM   155  H HE1  . PHE A 1 14  ? 28.93300 36.82700 7.88900   1.000 40.80000  ? 12  PHE A HE1  1 
ATOM   156  H HE2  . PHE A 1 14  ? 32.33400 35.37200 6.36500   1.000 46.50000  ? 12  PHE A HE2  1 
ATOM   157  H HZ   . PHE A 1 14  ? 31.17700 36.34800 8.11500   1.000 49.47000  ? 12  PHE A HZ   1 
ATOM   158  N N    . GLY A 1 15  ? 29.38300 38.50600 2.42800   1.000 39.58000  ? 13  GLY A N    1 
ATOM   159  C CA   . GLY A 1 15  ? 30.41400 39.27300 1.74600   1.000 43.58000  ? 13  GLY A CA   1 
ATOM   160  C C    . GLY A 1 15  ? 30.27900 39.13600 0.24500   1.000 40.73000  ? 13  GLY A C    1 
ATOM   161  O O    . GLY A 1 15  ? 29.17700 39.18100 -0.30800  1.000 39.48000  ? 13  GLY A O    1 
ATOM   162  H H    . GLY A 1 15  ? 28.88300 38.96000 2.96000   1.000 47.35000  ? 13  GLY A H    1 
ATOM   163  H HA2  . GLY A 1 15  ? 30.33700 40.21100 1.98200   1.000 52.15000  ? 13  GLY A HA2  1 
ATOM   164  H HA3  . GLY A 1 15  ? 31.29100 38.95400 2.01100   1.000 52.15000  ? 13  GLY A HA3  1 
ATOM   165  N N    . SER A 1 16  ? 31.41400 38.94300 -0.42500  1.000 40.22000  ? 14  SER A N    1 
ATOM   166  C CA   . SER A 1 16  ? 31.44900 38.79900 -1.87700  1.000 41.68000  ? 14  SER A CA   1 
ATOM   167  C C    . SER A 1 16  ? 31.12300 37.38300 -2.33900  1.000 44.03000  ? 14  SER A C    1 
ATOM   168  O O    . SER A 1 16  ? 31.28200 37.06800 -3.52500  1.000 34.70000  ? 14  SER A O    1 
ATOM   169  C CB   . SER A 1 16  ? 32.82600 39.20800 -2.41300  1.000 38.42000  ? 14  SER A CB   1 
ATOM   170  O OG   . SER A 1 16  ? 33.86000 38.48300 -1.77100  1.000 43.46000  ? 14  SER A OG   1 
ATOM   171  H H    . SER A 1 16  ? 32.18800 38.89100 -0.05300  1.000 48.12000  ? 14  SER A H    1 
ATOM   172  H HA   . SER A 1 16  ? 30.79000 39.39700 -2.26500  1.000 49.87000  ? 14  SER A HA   1 
ATOM   173  H HB2  . SER A 1 16  ? 32.85900 39.02900 -3.36500  1.000 45.96000  ? 14  SER A HB2  1 
ATOM   174  H HB3  . SER A 1 16  ? 32.95800 40.15500 -2.25100  1.000 45.96000  ? 14  SER A HB3  1 
ATOM   175  H HG   . SER A 1 16  ? 34.60800 38.71800 -2.07500  1.000 52.01000  ? 14  SER A HG   1 
ATOM   176  N N    . GLY A 1 17  ? 30.67200 36.52500 -1.43500  1.000 39.63000  ? 15  GLY A N    1 
ATOM   177  C CA   . GLY A 1 17  ? 30.38800 35.15000 -1.78100  1.000 36.63000  ? 15  GLY A CA   1 
ATOM   178  C C    . GLY A 1 17  ? 29.34000 34.54700 -0.87600  1.000 39.22000  ? 15  GLY A C    1 
ATOM   179  O O    . GLY A 1 17  ? 28.27400 35.13600 -0.67300  1.000 36.29000  ? 15  GLY A O    1 
ATOM   180  H H    . GLY A 1 17  ? 30.52200 36.71800 -0.61100  1.000 47.40000  ? 15  GLY A H    1 
ATOM   181  H HA2  . GLY A 1 17  ? 30.06800 35.10300 -2.69500  1.000 43.81000  ? 15  GLY A HA2  1 
ATOM   182  H HA3  . GLY A 1 17  ? 31.19900 34.62100 -1.71000  1.000 43.81000  ? 15  GLY A HA3  1 
ATOM   183  N N    . TRP A 1 18  ? 29.63600 33.38400 -0.30600  1.000 35.69000  ? 16  TRP A N    1 
ATOM   184  C CA   . TRP A 1 18  ? 28.64600 32.60600 0.42500   1.000 36.62000  ? 16  TRP A CA   1 
ATOM   185  C C    . TRP A 1 18  ? 29.29800 31.98800 1.64800   1.000 37.20000  ? 16  TRP A C    1 
ATOM   186  O O    . TRP A 1 18  ? 30.52200 32.00900 1.80300   1.000 29.09000  ? 16  TRP A O    1 
ATOM   187  C CB   . TRP A 1 18  ? 28.03500 31.53400 -0.49000  1.000 33.70000  ? 16  TRP A CB   1 
ATOM   188  C CG   . TRP A 1 18  ? 27.44900 32.13500 -1.72700  1.000 33.00000  ? 16  TRP A CG   1 
ATOM   189  C CD1  . TRP A 1 18  ? 28.09300 32.41700 -2.89800  1.000 39.73000  ? 16  TRP A CD1  1 
ATOM   190  C CD2  . TRP A 1 18  ? 26.09500 32.57000 -1.90000  1.000 38.15000  ? 16  TRP A CD2  1 
ATOM   191  N NE1  . TRP A 1 18  ? 27.21700 32.98800 -3.79600  1.000 39.89000  ? 16  TRP A NE1  1 
ATOM   192  C CE2  . TRP A 1 18  ? 25.98500 33.09400 -3.20300  1.000 36.83000  ? 16  TRP A CE2  1 
ATOM   193  C CE3  . TRP A 1 18  ? 24.96400 32.56400 -1.07500  1.000 45.40000  ? 16  TRP A CE3  1 
ATOM   194  C CZ2  . TRP A 1 18  ? 24.78800 33.59900 -3.70300  1.000 41.93000  ? 16  TRP A CZ2  1 
ATOM   195  C CZ3  . TRP A 1 18  ? 23.77800 33.06600 -1.57300  1.000 38.70000  ? 16  TRP A CZ3  1 
ATOM   196  C CH2  . TRP A 1 18  ? 23.69900 33.57600 -2.87500  1.000 41.45000  ? 16  TRP A CH2  1 
ATOM   197  H H    . TRP A 1 18  ? 30.41500 33.02000 -0.33000  1.000 42.68000  ? 16  TRP A H    1 
ATOM   198  H HA   . TRP A 1 18  ? 27.93300 33.19100 0.72600   1.000 43.79000  ? 16  TRP A HA   1 
ATOM   199  H HB2  . TRP A 1 18  ? 28.72700 30.90800 -0.75500  1.000 40.30000  ? 16  TRP A HB2  1 
ATOM   200  H HB3  . TRP A 1 18  ? 27.32900 31.07100 -0.01400  1.000 40.30000  ? 16  TRP A HB3  1 
ATOM   201  H HD1  . TRP A 1 18  ? 28.99100 32.24400 -3.06700  1.000 47.53000  ? 16  TRP A HD1  1 
ATOM   202  H HE1  . TRP A 1 18  ? 27.41200 33.23800 -4.59600  1.000 47.72000  ? 16  TRP A HE1  1 
ATOM   203  H HE3  . TRP A 1 18  ? 25.01000 32.22500 -0.21000  1.000 54.33000  ? 16  TRP A HE3  1 
ATOM   204  H HZ2  . TRP A 1 18  ? 24.73100 33.93800 -4.56700  1.000 50.17000  ? 16  TRP A HZ2  1 
ATOM   205  H HZ3  . TRP A 1 18  ? 23.01800 33.06500 -1.03600  1.000 46.29000  ? 16  TRP A HZ3  1 
ATOM   206  H HH2  . TRP A 1 18  ? 22.88700 33.90800 -3.18400  1.000 49.59000  ? 16  TRP A HH2  1 
ATOM   207  N N    . GLY A 1 19  ? 28.45000 31.47100 2.54400   1.000 37.65000  ? 17  GLY A N    1 
ATOM   208  C CA   . GLY A 1 19  ? 28.88900 30.69000 3.68200   1.000 37.58000  ? 17  GLY A CA   1 
ATOM   209  C C    . GLY A 1 19  ? 27.82000 29.68100 4.03800   1.000 37.81000  ? 17  GLY A C    1 
ATOM   210  O O    . GLY A 1 19  ? 26.68800 29.75400 3.55300   1.000 34.04000  ? 17  GLY A O    1 
ATOM   211  H H    . GLY A 1 19  ? 27.59600 31.56800 2.50500   1.000 45.03000  ? 17  GLY A H    1 
ATOM   212  H HA2  . GLY A 1 19  ? 29.70400 30.21400 3.45700   1.000 44.94000  ? 17  GLY A HA2  1 
ATOM   213  H HA3  . GLY A 1 19  ? 29.06500 31.26700 4.43800   1.000 44.94000  ? 17  GLY A HA3  1 
ATOM   214  N N    . PHE A 1 20  ? 28.18300 28.74900 4.92400   1.000 34.45000  ? 18  PHE A N    1 
ATOM   215  C CA   . PHE A 1 20  ? 27.35700 27.57800 5.19400   1.000 33.03000  ? 18  PHE A CA   1 
ATOM   216  C C    . PHE A 1 20  ? 27.26400 27.30500 6.68200   1.000 35.47000  ? 18  PHE A C    1 
ATOM   217  O O    . PHE A 1 20  ? 28.28900 27.22100 7.36400   1.000 29.93000  ? 18  PHE A O    1 
ATOM   218  C CB   . PHE A 1 20  ? 27.95300 26.34700 4.49000   1.000 36.83000  ? 18  PHE A CB   1 
ATOM   219  C CG   . PHE A 1 20  ? 27.17800 25.07600 4.68800   1.000 36.73000  ? 18  PHE A CG   1 
ATOM   220  C CD1  . PHE A 1 20  ? 25.94600 24.90200 4.08400   1.000 31.19000  ? 18  PHE A CD1  1 
ATOM   221  C CD2  . PHE A 1 20  ? 27.69700 24.04100 5.44900   1.000 35.93000  ? 18  PHE A CD2  1 
ATOM   222  C CE1  . PHE A 1 20  ? 25.23900 23.71600 4.24400   1.000 35.00000  ? 18  PHE A CE1  1 
ATOM   223  C CE2  . PHE A 1 20  ? 26.98800 22.85700 5.61600   1.000 38.25000  ? 18  PHE A CE2  1 
ATOM   224  C CZ   . PHE A 1 20  ? 25.76100 22.69800 5.00900   1.000 35.61000  ? 18  PHE A CZ   1 
ATOM   225  H H    . PHE A 1 20  ? 28.91000 28.77500 5.38300   1.000 41.19000  ? 18  PHE A H    1 
ATOM   226  H HA   . PHE A 1 20  ? 26.46300 27.72400 4.85100   1.000 39.48000  ? 18  PHE A HA   1 
ATOM   227  H HB2  . PHE A 1 20  ? 27.99000 26.52300 3.53700   1.000 44.05000  ? 18  PHE A HB2  1 
ATOM   228  H HB3  . PHE A 1 20  ? 28.85000 26.20000 4.82900   1.000 44.05000  ? 18  PHE A HB3  1 
ATOM   229  H HD1  . PHE A 1 20  ? 25.59000 25.58400 3.56200   1.000 37.28000  ? 18  PHE A HD1  1 
ATOM   230  H HD2  . PHE A 1 20  ? 28.52700 24.14000 5.85700   1.000 42.97000  ? 18  PHE A HD2  1 
ATOM   231  H HE1  . PHE A 1 20  ? 24.40800 23.61300 3.83900   1.000 41.85000  ? 18  PHE A HE1  1 
ATOM   232  H HE2  . PHE A 1 20  ? 27.34300 22.17000 6.13200   1.000 45.75000  ? 18  PHE A HE2  1 
ATOM   233  H HZ   . PHE A 1 20  ? 25.28400 21.90800 5.12300   1.000 42.58000  ? 18  PHE A HZ   1 
ATOM   234  N N    . TRP A 1 21  ? 26.03300 27.15300 7.17700   1.000 36.38000  ? 19  TRP A N    1 
ATOM   235  C CA   . TRP A 1 21  ? 25.80300 26.80300 8.57200   1.000 39.50000  ? 19  TRP A CA   1 
ATOM   236  C C    . TRP A 1 21  ? 26.00800 25.30100 8.76100   1.000 39.60000  ? 19  TRP A C    1 
ATOM   237  O O    . TRP A 1 21  ? 25.15200 24.50100 8.35200   1.000 39.25000  ? 19  TRP A O    1 
ATOM   238  C CB   . TRP A 1 21  ? 24.38900 27.21400 9.00600   1.000 36.42000  ? 19  TRP A CB   1 
ATOM   239  C CG   . TRP A 1 21  ? 24.19600 28.69600 9.17400   1.000 32.08000  ? 19  TRP A CG   1 
ATOM   240  C CD1  . TRP A 1 21  ? 23.52000 29.53300 8.33600   1.000 35.12000  ? 19  TRP A CD1  1 
ATOM   241  C CD2  . TRP A 1 21  ? 24.67700 29.50900 10.25100  1.000 28.15000  ? 19  TRP A CD2  1 
ATOM   242  N NE1  . TRP A 1 21  ? 23.55800 30.82400 8.82300   1.000 37.51000  ? 19  TRP A NE1  1 
ATOM   243  C CE2  . TRP A 1 21  ? 24.26000 30.83100 9.99800   1.000 35.32000  ? 19  TRP A CE2  1 
ATOM   244  C CE3  . TRP A 1 21  ? 25.41900 29.24800 11.40700  1.000 32.42000  ? 19  TRP A CE3  1 
ATOM   245  C CZ2  . TRP A 1 21  ? 24.56700 31.88600 10.85500  1.000 34.99000  ? 19  TRP A CZ2  1 
ATOM   246  C CZ3  . TRP A 1 21  ? 25.72000 30.29700 12.25000  1.000 36.14000  ? 19  TRP A CZ3  1 
ATOM   247  C CH2  . TRP A 1 21  ? 25.29200 31.60000 11.97100  1.000 33.16000  ? 19  TRP A CH2  1 
ATOM   248  H H    . TRP A 1 21  ? 25.31200 27.25000 6.71700   1.000 43.51000  ? 19  TRP A H    1 
ATOM   249  H HA   . TRP A 1 21  ? 26.44300 27.27200 9.13200   1.000 47.25000  ? 19  TRP A HA   1 
ATOM   250  H HB2  . TRP A 1 21  ? 23.75800 26.90900 8.33600   1.000 43.56000  ? 19  TRP A HB2  1 
ATOM   251  H HB3  . TRP A 1 21  ? 24.19100 26.79300 9.85700   1.000 43.56000  ? 19  TRP A HB3  1 
ATOM   252  H HD1  . TRP A 1 21  ? 23.10100 29.27400 7.54800   1.000 42.00000  ? 19  TRP A HD1  1 
ATOM   253  H HE1  . TRP A 1 21  ? 23.19700 31.51000 8.45100   1.000 44.87000  ? 19  TRP A HE1  1 
ATOM   254  H HE3  . TRP A 1 21  ? 25.71000 28.38600 11.60000  1.000 38.76000  ? 19  TRP A HE3  1 
ATOM   255  H HZ2  . TRP A 1 21  ? 24.28300 32.75300 10.67300  1.000 41.84000  ? 19  TRP A HZ2  1 
ATOM   256  H HZ3  . TRP A 1 21  ? 26.21500 30.13400 13.02200  1.000 43.23000  ? 19  TRP A HZ3  1 
ATOM   257  H HH2  . TRP A 1 21  ? 25.50800 32.28600 12.56000  1.000 39.65000  ? 19  TRP A HH2  1 
ATOM   258  N N    . VAL A 1 22  ? 27.13000 24.91400 9.37200   1.000 38.16000  ? 20  VAL A N    1 
ATOM   259  C CA   . VAL A 1 22  ? 27.33000 23.50100 9.68500   1.000 32.42000  ? 20  VAL A CA   1 
ATOM   260  C C    . VAL A 1 22  ? 26.43400 23.08600 10.84300  1.000 39.48000  ? 20  VAL A C    1 
ATOM   261  O O    . VAL A 1 22  ? 26.00000 21.93100 10.92700  1.000 43.78000  ? 20  VAL A O    1 
ATOM   262  C CB   . VAL A 1 22  ? 28.80900 23.23400 10.00700  1.000 37.99000  ? 20  VAL A CB   1 
ATOM   263  C CG1  . VAL A 1 22  ? 29.03600 21.76500 10.33800  1.000 39.78000  ? 20  VAL A CG1  1 
ATOM   264  C CG2  . VAL A 1 22  ? 29.68600 23.65500 8.84400   1.000 37.99000  ? 20  VAL A CG2  1 
ATOM   265  H H    . VAL A 1 22  ? 27.77200 25.43500 9.61000   1.000 45.64000  ? 20  VAL A H    1 
ATOM   266  H HA   . VAL A 1 22  ? 27.08900 22.96800 8.91200   1.000 38.75000  ? 20  VAL A HA   1 
ATOM   267  H HB   . VAL A 1 22  ? 29.06500 23.76000 10.78200  1.000 45.44000  ? 20  VAL A HB   1 
ATOM   268  H HG11 . VAL A 1 22  ? 29.99000 21.59100 10.35800  1.000 47.59000  ? 20  VAL A HG11 1 
ATOM   269  H HG12 . VAL A 1 22  ? 28.64700 21.57000 11.20500  1.000 47.59000  ? 20  VAL A HG12 1 
ATOM   270  H HG13 . VAL A 1 22  ? 28.61500 21.21900 9.65500   1.000 47.59000  ? 20  VAL A HG13 1 
ATOM   271  H HG21 . VAL A 1 22  ? 30.60300 23.40300 9.03300   1.000 45.44000  ? 20  VAL A HG21 1 
ATOM   272  H HG22 . VAL A 1 22  ? 29.37800 23.20800 8.03900   1.000 45.44000  ? 20  VAL A HG22 1 
ATOM   273  H HG23 . VAL A 1 22  ? 29.62400 24.61600 8.73200   1.000 45.44000  ? 20  VAL A HG23 1 
ATOM   274  N N    . SER A 1 23  ? 26.14500 24.00900 11.74900  1.000 43.12000  ? 21  SER A N    1 
ATOM   275  C CA   . SER A 1 23  ? 25.37200 23.73700 12.95300  1.000 41.00000  ? 21  SER A CA   1 
ATOM   276  C C    . SER A 1 23  ? 24.73700 25.05000 13.39000  1.000 43.87000  ? 21  SER A C    1 
ATOM   277  O O    . SER A 1 23  ? 24.98700 26.09900 12.77900  1.000 39.19000  ? 21  SER A O    1 
ATOM   278  C CB   . SER A 1 23  ? 26.26000 23.15400 14.04800  1.000 39.06000  ? 21  SER A CB   1 
ATOM   279  O OG   . SER A 1 23  ? 26.94700 24.17200 14.75000  1.000 45.19000  ? 21  SER A OG   1 
ATOM   280  H H    . SER A 1 23  ? 26.39400 24.83000 11.68600  1.000 51.60000  ? 21  SER A H    1 
ATOM   281  H HA   . SER A 1 23  ? 24.66700 23.10300 12.75300  1.000 49.05000  ? 21  SER A HA   1 
ATOM   282  H HB2  . SER A 1 23  ? 25.71400 22.65000 14.67000  1.000 46.73000  ? 21  SER A HB2  1 
ATOM   283  H HB3  . SER A 1 23  ? 26.91300 22.56600 13.63700  1.000 46.73000  ? 21  SER A HB3  1 
ATOM   284  H HG   . SER A 1 23  ? 27.42900 23.83200 15.34800  1.000 54.08000  ? 21  SER A HG   1 
ATOM   285  N N    . PRO A 1 24  ? 23.89900 25.03900 14.43200  1.000 40.73000  ? 22  PRO A N    1 
ATOM   286  C CA   . PRO A 1 24  ? 23.30500 26.31000 14.89000  1.000 43.04000  ? 22  PRO A CA   1 
ATOM   287  C C    . PRO A 1 24  ? 24.34000 27.36200 15.19900  1.000 46.66000  ? 22  PRO A C    1 
ATOM   288  O O    . PRO A 1 24  ? 24.02200 28.56900 15.10900  1.000 41.68000  ? 22  PRO A O    1 
ATOM   289  C CB   . PRO A 1 24  ? 22.52300 25.89500 16.14400  1.000 43.67000  ? 22  PRO A CB   1 
ATOM   290  C CG   . PRO A 1 24  ? 22.19300 24.44400 15.91200  1.000 47.24000  ? 22  PRO A CG   1 
ATOM   291  C CD   . PRO A 1 24  ? 23.36600 23.86800 15.15100  1.000 45.45000  ? 22  PRO A CD   1 
ATOM   292  H HA   . PRO A 1 24  ? 22.68700 26.65200 14.22500  1.000 51.51000  ? 22  PRO A HA   1 
ATOM   293  H HB2  . PRO A 1 24  ? 23.08100 26.00100 16.93000  1.000 52.26000  ? 22  PRO A HB2  1 
ATOM   294  H HB3  . PRO A 1 24  ? 21.71400 26.42600 16.21900  1.000 52.26000  ? 22  PRO A HB3  1 
ATOM   295  H HG2  . PRO A 1 24  ? 22.08800 23.99500 16.76500  1.000 56.54000  ? 22  PRO A HG2  1 
ATOM   296  H HG3  . PRO A 1 24  ? 21.38000 24.37600 15.38800  1.000 56.54000  ? 22  PRO A HG3  1 
ATOM   297  H HD2  . PRO A 1 24  ? 24.02600 23.51900 15.76900  1.000 54.40000  ? 22  PRO A HD2  1 
ATOM   298  H HD3  . PRO A 1 24  ? 23.06600 23.19000 14.52400  1.000 54.40000  ? 22  PRO A HD3  1 
ATOM   299  N N    . SER A 1 25  ? 25.57400 26.97200 15.52100  1.000 41.77000  ? 23  SER A N    1 
ATOM   300  C CA   . SER A 1 25  ? 26.58500 27.87700 16.02300  1.000 43.81000  ? 23  SER A CA   1 
ATOM   301  C C    . SER A 1 25  ? 27.81900 28.00000 15.14000  1.000 40.76000  ? 23  SER A C    1 
ATOM   302  O O    . SER A 1 25  ? 28.63300 28.89700 15.38500  1.000 38.67000  ? 23  SER A O    1 
ATOM   303  C CB   . SER A 1 25  ? 27.03500 27.43000 17.42700  1.000 44.75000  ? 23  SER A CB   1 
ATOM   304  O OG   . SER A 1 25  ? 26.01500 27.64600 18.38800  1.000 62.63000  ? 23  SER A OG   1 
ATOM   305  H H    . SER A 1 25  ? 25.85000 26.16000 15.45400  1.000 49.97000  ? 23  SER A H    1 
ATOM   306  H HA   . SER A 1 25  ? 26.19700 28.76200 16.10800  1.000 52.43000  ? 23  SER A HA   1 
ATOM   307  H HB2  . SER A 1 25  ? 27.24800 26.48400 17.40200  1.000 53.55000  ? 23  SER A HB2  1 
ATOM   308  H HB3  . SER A 1 25  ? 27.82000 27.93900 17.68200  1.000 53.55000  ? 23  SER A HB3  1 
ATOM   309  H HG   . SER A 1 25  ? 26.27600 27.39600 19.14600  1.000 75.02000  ? 23  SER A HG   1 
ATOM   310  N N    . LEU A 1 26  ? 27.97500 27.15700 14.12100  1.000 38.02000  ? 24  LEU A N    1 
ATOM   311  C CA   . LEU A 1 26  ? 29.20300 27.07400 13.33800  1.000 34.89000  ? 24  LEU A CA   1 
ATOM   312  C C    . LEU A 1 26  ? 28.92400 27.42700 11.88500  1.000 33.64000  ? 24  LEU A C    1 
ATOM   313  O O    . LEU A 1 26  ? 28.12200 26.76000 11.22600  1.000 38.29000  ? 24  LEU A O    1 
ATOM   314  C CB   . LEU A 1 26  ? 29.80200 25.66800 13.43300  1.000 40.30000  ? 24  LEU A CB   1 
ATOM   315  C CG   . LEU A 1 26  ? 31.18700 25.48100 12.81900  1.000 38.43000  ? 24  LEU A CG   1 
ATOM   316  C CD1  . LEU A 1 26  ? 32.21300 26.37900 13.48200  1.000 40.81000  ? 24  LEU A CD1  1 
ATOM   317  C CD2  . LEU A 1 26  ? 31.59200 24.02400 12.92900  1.000 46.69000  ? 24  LEU A CD2  1 
ATOM   318  H H    . LEU A 1 26  ? 27.36700 26.60900 13.85900  1.000 45.47000  ? 24  LEU A H    1 
ATOM   319  H HA   . LEU A 1 26  ? 29.84900 27.70800 13.68600  1.000 41.72000  ? 24  LEU A HA   1 
ATOM   320  H HB2  . LEU A 1 26  ? 29.86800 25.42800 14.37100  1.000 48.22000  ? 24  LEU A HB2  1 
ATOM   321  H HB3  . LEU A 1 26  ? 29.20200 25.05100 12.98600  1.000 48.22000  ? 24  LEU A HB3  1 
ATOM   322  H HG   . LEU A 1 26  ? 31.15000 25.71100 11.87800  1.000 45.96000  ? 24  LEU A HG   1 
ATOM   323  H HD11 . LEU A 1 26  ? 33.09600 26.12900 13.17000  1.000 48.83000  ? 24  LEU A HD11 1 
ATOM   324  H HD12 . LEU A 1 26  ? 32.02900 27.30100 13.24400  1.000 48.83000  ? 24  LEU A HD12 1 
ATOM   325  H HD13 . LEU A 1 26  ? 32.15800 26.26600 14.44300  1.000 48.83000  ? 24  LEU A HD13 1 
ATOM   326  H HD21 . LEU A 1 26  ? 32.47200 23.91100 12.53600  1.000 55.88000  ? 24  LEU A HD21 1 
ATOM   327  H HD22 . LEU A 1 26  ? 31.61300 23.77100 13.86500  1.000 55.88000  ? 24  LEU A HD22 1 
ATOM   328  H HD23 . LEU A 1 26  ? 30.94400 23.48000 12.45300  1.000 55.88000  ? 24  LEU A HD23 1 
ATOM   329  N N    . PHE A 1 27  ? 29.60900 28.45200 11.38500  1.000 31.61000  ? 25  PHE A N    1 
ATOM   330  C CA   . PHE A 1 27  ? 29.44000 28.99800 10.04400  1.000 29.86000  ? 25  PHE A CA   1 
ATOM   331  C C    . PHE A 1 27  ? 30.79100 28.97500 9.34800   1.000 34.17000  ? 25  PHE A C    1 
ATOM   332  O O    . PHE A 1 27  ? 31.77300 29.49500 9.88900   1.000 35.47000  ? 25  PHE A O    1 
ATOM   333  C CB   . PHE A 1 27  ? 28.89800 30.43000 10.14500  1.000 34.15000  ? 25  PHE A CB   1 
ATOM   334  C CG   . PHE A 1 27  ? 28.47800 31.03600 8.83400   1.000 34.73000  ? 25  PHE A CG   1 
ATOM   335  C CD1  . PHE A 1 27  ? 27.27600 30.68600 8.24400   1.000 36.80000  ? 25  PHE A CD1  1 
ATOM   336  C CD2  . PHE A 1 27  ? 29.27300 31.98400 8.21000   1.000 34.60000  ? 25  PHE A CD2  1 
ATOM   337  C CE1  . PHE A 1 27  ? 26.88000 31.25600 7.05000   1.000 35.68000  ? 25  PHE A CE1  1 
ATOM   338  C CE2  . PHE A 1 27  ? 28.88600 32.55300 7.01700   1.000 37.55000  ? 25  PHE A CE2  1 
ATOM   339  C CZ   . PHE A 1 27  ? 27.68400 32.19100 6.43900   1.000 36.81000  ? 25  PHE A CZ   1 
ATOM   340  H H    . PHE A 1 27  ? 30.21200 28.87000 11.83500  1.000 37.79000  ? 25  PHE A H    1 
ATOM   341  H HA   . PHE A 1 27  ? 28.81300 28.45600 9.54000   1.000 35.68000  ? 25  PHE A HA   1 
ATOM   342  H HB2  . PHE A 1 27  ? 28.12400 30.42800 10.72800  1.000 40.84000  ? 25  PHE A HB2  1 
ATOM   343  H HB3  . PHE A 1 27  ? 29.58900 30.99700 10.52200  1.000 40.84000  ? 25  PHE A HB3  1 
ATOM   344  H HD1  . PHE A 1 27  ? 26.72900 30.05700 8.65600   1.000 44.01000  ? 25  PHE A HD1  1 
ATOM   345  H HD2  . PHE A 1 27  ? 30.08100 32.23300 8.59800   1.000 41.37000  ? 25  PHE A HD2  1 
ATOM   346  H HE1  . PHE A 1 27  ? 26.07300 31.00800 6.66000   1.000 42.67000  ? 25  PHE A HE1  1 
ATOM   347  H HE2  . PHE A 1 27  ? 29.43000 33.18500 6.60500   1.000 44.92000  ? 25  PHE A HE2  1 
ATOM   348  H HZ   . PHE A 1 27  ? 27.42200 32.57300 5.63200   1.000 44.02000  ? 25  PHE A HZ   1 
ATOM   349  N N    . ILE A 1 28  ? 30.85800 28.35800 8.16800   1.000 32.73000  ? 26  ILE A N    1 
ATOM   350  C CA   . ILE A 1 28  ? 32.12600 28.27500 7.44700   1.000 29.00000  ? 26  ILE A CA   1 
ATOM   351  C C    . ILE A 1 28  ? 32.00400 29.03300 6.12900   1.000 37.30000  ? 26  ILE A C    1 
ATOM   352  O O    . ILE A 1 28  ? 30.91800 29.15600 5.54800   1.000 30.96000  ? 26  ILE A O    1 
ATOM   353  C CB   . ILE A 1 28  ? 32.58800 26.82500 7.18600   1.000 31.41000  ? 26  ILE A CB   1 
ATOM   354  C CG1  . ILE A 1 28  ? 31.56700 26.07400 6.33300   1.000 34.79000  ? 26  ILE A CG1  1 
ATOM   355  C CG2  . ILE A 1 28  ? 32.82000 26.09300 8.50000   1.000 33.31000  ? 26  ILE A CG2  1 
ATOM   356  C CD1  . ILE A 1 28  ? 32.00200 24.67400 5.98100   1.000 39.79000  ? 26  ILE A CD1  1 
ATOM   357  H H    . ILE A 1 28  ? 30.19500 27.98500 7.76800   1.000 39.13000  ? 26  ILE A H    1 
ATOM   358  H HA   . ILE A 1 28  ? 32.81600 28.70900 7.97000   1.000 34.65000  ? 26  ILE A HA   1 
ATOM   359  H HB   . ILE A 1 28  ? 33.42700 26.85500 6.70100   1.000 37.54000  ? 26  ILE A HB   1 
ATOM   360  H HG12 . ILE A 1 28  ? 30.73300 26.01200 6.82400   1.000 41.60000  ? 26  ILE A HG12 1 
ATOM   361  H HG13 . ILE A 1 28  ? 31.42600 26.55300 5.50200   1.000 41.60000  ? 26  ILE A HG13 1 
ATOM   362  H HG21 . ILE A 1 28  ? 33.28400 25.26000 8.32200   1.000 39.83000  ? 26  ILE A HG21 1 
ATOM   363  H HG22 . ILE A 1 28  ? 33.35900 26.65300 9.08000   1.000 39.83000  ? 26  ILE A HG22 1 
ATOM   364  H HG23 . ILE A 1 28  ? 31.96300 25.91400 8.91700   1.000 39.83000  ? 26  ILE A HG23 1 
ATOM   365  H HD11 . ILE A 1 28  ? 31.39300 24.31200 5.31800   1.000 47.60000  ? 26  ILE A HD11 1 
ATOM   366  H HD12 . ILE A 1 28  ? 32.90200 24.70500 5.62100   1.000 47.60000  ? 26  ILE A HD12 1 
ATOM   367  H HD13 . ILE A 1 28  ? 31.98300 24.12600 6.78100   1.000 47.60000  ? 26  ILE A HD13 1 
ATOM   368  N N    . THR A 1 29  ? 33.13700 29.54600 5.65700   1.000 37.94000  ? 27  THR A N    1 
ATOM   369  C CA   . THR A 1 29  ? 33.16700 30.28400 4.40100   1.000 28.82000  ? 27  THR A CA   1 
ATOM   370  C C    . THR A 1 29  ? 34.60700 30.30300 3.90400   1.000 29.92000  ? 27  THR A C    1 
ATOM   371  O O    . THR A 1 29  ? 35.48200 29.63100 4.45700   1.000 31.96000  ? 27  THR A O    1 
ATOM   372  C CB   . THR A 1 29  ? 32.60800 31.69800 4.58400   1.000 30.44000  ? 27  THR A CB   1 
ATOM   373  O OG1  . THR A 1 29  ? 32.71600 32.42800 3.34900   1.000 36.44000  ? 27  THR A OG1  1 
ATOM   374  C CG2  . THR A 1 29  ? 33.36700 32.43200 5.66000   1.000 38.48000  ? 27  THR A CG2  1 
ATOM   375  H H    . THR A 1 29  ? 33.90000 29.47900 6.04500   1.000 45.38000  ? 27  THR A H    1 
ATOM   376  H HA   . THR A 1 29  ? 32.62200 29.82300 3.74400   1.000 34.44000  ? 27  THR A HA   1 
ATOM   377  H HB   . THR A 1 29  ? 31.67600 31.64500 4.84800   1.000 36.39000  ? 27  THR A HB   1 
ATOM   378  H HG1  . THR A 1 29  ? 32.27800 32.03900 2.74600   1.000 43.58000  ? 27  THR A HG1  1 
ATOM   379  H HG21 . THR A 1 29  ? 33.00600 33.32500 5.76600   1.000 46.03000  ? 27  THR A HG21 1 
ATOM   380  H HG22 . THR A 1 29  ? 33.29000 31.96000 6.50400   1.000 46.03000  ? 27  THR A HG22 1 
ATOM   381  H HG23 . THR A 1 29  ? 34.30400 32.50000 5.42100   1.000 46.03000  ? 27  THR A HG23 1 
ATOM   382  N N    . SER A 1 30  ? 34.85000 31.09000 2.86500   1.000 31.23000  ? 28  SER A N    1 
ATOM   383  C CA   . SER A 1 30  ? 36.16800 31.23400 2.26700   1.000 34.07000  ? 28  SER A CA   1 
ATOM   384  C C    . SER A 1 30  ? 36.84400 32.50000 2.77600   1.000 32.97000  ? 28  SER A C    1 
ATOM   385  O O    . SER A 1 30  ? 36.20500 33.54800 2.92000   1.000 35.75000  ? 28  SER A O    1 
ATOM   386  C CB   . SER A 1 30  ? 36.06800 31.29200 0.74000   1.000 35.90000  ? 28  SER A CB   1 
ATOM   387  O OG   . SER A 1 30  ? 37.18200 31.97600 0.20200   1.000 40.68000  ? 28  SER A OG   1 
ATOM   388  H H    . SER A 1 30  ? 34.24700 31.56600 2.47700   1.000 37.33000  ? 28  SER A H    1 
ATOM   389  H HA   . SER A 1 30  ? 36.71700 30.47300 2.50900   1.000 40.74000  ? 28  SER A HA   1 
ATOM   390  H HB2  . SER A 1 30  ? 36.05000 30.38800 0.38900   1.000 42.93000  ? 28  SER A HB2  1 
ATOM   391  H HB3  . SER A 1 30  ? 35.25600 31.76200 0.49300   1.000 42.93000  ? 28  SER A HB3  1 
ATOM   392  H HG   . SER A 1 30  ? 37.12300 32.00500 -0.63500  1.000 48.67000  ? 28  SER A HG   1 
ATOM   393  N N    . THR A 1 31  ? 38.14900 32.40200 3.02700   1.000 34.95000  ? 29  THR A N    1 
ATOM   394  C CA   . THR A 1 31  ? 38.89400 33.56600 3.48900   1.000 34.72000  ? 29  THR A CA   1 
ATOM   395  C C    . THR A 1 31  ? 38.76000 34.73700 2.52700   1.000 35.97000  ? 29  THR A C    1 
ATOM   396  O O    . THR A 1 31  ? 38.74000 35.89400 2.96300   1.000 40.40000  ? 29  THR A O    1 
ATOM   397  C CB   . THR A 1 31  ? 40.36100 33.18700 3.67900   1.000 40.65000  ? 29  THR A CB   1 
ATOM   398  O OG1  . THR A 1 31  ? 40.44800 32.05900 4.56200   1.000 35.13000  ? 29  THR A OG1  1 
ATOM   399  C CG2  . THR A 1 31  ? 41.13700 34.34400 4.26400   1.000 36.83000  ? 29  THR A CG2  1 
ATOM   400  H H    . THR A 1 31  ? 38.61700 31.68600 2.93700   1.000 41.79000  ? 29  THR A H    1 
ATOM   401  H HA   . THR A 1 31  ? 38.54300 33.84300 4.34900   1.000 41.52000  ? 29  THR A HA   1 
ATOM   402  H HB   . THR A 1 31  ? 40.75000 32.95900 2.82100   1.000 48.64000  ? 29  THR A HB   1 
ATOM   403  H HG1  . THR A 1 31  ? 41.25200 31.84300 4.67300   1.000 42.01000  ? 29  THR A HG1  1 
ATOM   404  H HG21 . THR A 1 31  ? 42.01900 34.04600 4.53600   1.000 44.05000  ? 29  THR A HG21 1 
ATOM   405  H HG22 . THR A 1 31  ? 41.23400 35.04900 3.60500   1.000 44.05000  ? 29  THR A HG22 1 
ATOM   406  H HG23 . THR A 1 31  ? 40.67100 34.69600 5.03900   1.000 44.05000  ? 29  THR A HG23 1 
ATOM   407  N N    . HIS A 1 32  ? 38.64700 34.47000 1.22400   1.000 37.89000  ? 30  HIS A N    1 
ATOM   408  C CA   . HIS A 1 32  ? 38.53400 35.54300 0.24200   1.000 34.35000  ? 30  HIS A CA   1 
ATOM   409  C C    . HIS A 1 32  ? 37.19700 36.26800 0.29500   1.000 40.99000  ? 30  HIS A C    1 
ATOM   410  O O    . HIS A 1 32  ? 37.06400 37.33600 -0.31100  1.000 40.23000  ? 30  HIS A O    1 
ATOM   411  C CB   . HIS A 1 32  ? 38.73300 34.98300 -1.17000  1.000 45.92000  ? 30  HIS A CB   1 
ATOM   412  C CG   . HIS A 1 32  ? 40.11500 35.17300 -1.70700  1.000 45.40000  ? 30  HIS A CG   1 
ATOM   413  N ND1  . HIS A 1 32  ? 41.20600 34.50200 -1.19700  1.000 42.73000  ? 30  HIS A ND1  1 
ATOM   414  C CD2  . HIS A 1 32  ? 40.58600 35.96200 -2.70000  1.000 46.64000  ? 30  HIS A CD2  1 
ATOM   415  C CE1  . HIS A 1 32  ? 42.29200 34.87100 -1.85300  1.000 49.30000  ? 30  HIS A CE1  1 
ATOM   416  N NE2  . HIS A 1 32  ? 41.94300 35.75500 -2.77100  1.000 49.28000  ? 30  HIS A NE2  1 
ATOM   417  H H    . HIS A 1 32  ? 38.63300 33.67800 0.88900   1.000 45.32000  ? 30  HIS A H    1 
ATOM   418  H HA   . HIS A 1 32  ? 39.23400 36.19500 0.40600   1.000 41.08000  ? 30  HIS A HA   1 
ATOM   419  H HB2  . HIS A 1 32  ? 38.54700 34.03100 -1.16100  1.000 54.95000  ? 30  HIS A HB2  1 
ATOM   420  H HB3  . HIS A 1 32  ? 38.11800 35.43100 -1.77300  1.000 54.95000  ? 30  HIS A HB3  1 
ATOM   421  H HD2  . HIS A 1 32  ? 40.08700 36.53700 -3.23200  1.000 55.82000  ? 30  HIS A HD2  1 
ATOM   422  H HE1  . HIS A 1 32  ? 43.15400 34.55800 -1.69800  1.000 59.01000  ? 30  HIS A HE1  1 
ATOM   423  H HE2  . HIS A 1 32  ? 42.47900 36.13700 -3.32500  1.000 58.99000  ? 30  HIS A HE2  1 
ATOM   424  N N    . VAL A 1 33  ? 36.21200 35.72200 1.00500   1.000 34.25000  ? 31  VAL A N    1 
ATOM   425  C CA   . VAL A 1 33  ? 34.86000 36.24700 0.98100   1.000 37.24000  ? 31  VAL A CA   1 
ATOM   426  C C    . VAL A 1 33  ? 34.47200 36.97200 2.26400   1.000 39.74000  ? 31  VAL A C    1 
ATOM   427  O O    . VAL A 1 33  ? 33.65300 37.89900 2.21000   1.000 35.59000  ? 31  VAL A O    1 
ATOM   428  C CB   . VAL A 1 33  ? 33.88300 35.09000 0.68100   1.000 37.61000  ? 31  VAL A CB   1 
ATOM   429  C CG1  . VAL A 1 33  ? 32.50000 35.41000 1.17300   1.000 52.24000  ? 31  VAL A CG1  1 
ATOM   430  C CG2  . VAL A 1 33  ? 33.87500 34.79500 -0.80600  1.000 41.95000  ? 31  VAL A CG2  1 
ATOM   431  H H    . VAL A 1 33  ? 36.30700 35.03600 1.51500   1.000 40.95000  ? 31  VAL A H    1 
ATOM   432  H HA   . VAL A 1 33  ? 34.78600 36.88400 0.25400   1.000 44.54000  ? 31  VAL A HA   1 
ATOM   433  H HB   . VAL A 1 33  ? 34.18800 34.29300 1.14300   1.000 44.98000  ? 31  VAL A HB   1 
ATOM   434  H HG11 . VAL A 1 33  ? 31.87300 34.79700 0.75800   1.000 62.54000  ? 31  VAL A HG11 1 
ATOM   435  H HG12 . VAL A 1 33  ? 32.46600 35.30700 2.13700   1.000 62.54000  ? 31  VAL A HG12 1 
ATOM   436  H HG13 . VAL A 1 33  ? 32.28200 36.32000 0.92200   1.000 62.54000  ? 31  VAL A HG13 1 
ATOM   437  H HG21 . VAL A 1 33  ? 33.30900 34.02400 -0.97100  1.000 50.19000  ? 31  VAL A HG21 1 
ATOM   438  H HG22 . VAL A 1 33  ? 33.52900 35.56800 -1.28000  1.000 50.19000  ? 31  VAL A HG22 1 
ATOM   439  H HG23 . VAL A 1 33  ? 34.78200 34.60700 -1.09500  1.000 50.19000  ? 31  VAL A HG23 1 
ATOM   440  N N    . ILE A 1 34  ? 35.03100 36.59500 3.40900   1.000 38.44000  ? 32  ILE A N    1 
ATOM   441  C CA   . ILE A 1 34  ? 34.59600 37.19400 4.68000   1.000 43.39000  ? 32  ILE A CA   1 
ATOM   442  C C    . ILE A 1 34  ? 34.85300 38.69600 4.65200   1.000 40.96000  ? 32  ILE A C    1 
ATOM   443  O O    . ILE A 1 34  ? 35.94800 39.13100 4.24700   1.000 39.83000  ? 32  ILE A O    1 
ATOM   444  C CB   . ILE A 1 34  ? 35.32500 36.52100 5.85900   1.000 39.12000  ? 32  ILE A CB   1 
ATOM   445  C CG1  . ILE A 1 34  ? 34.98700 37.20500 7.18100   1.000 44.76000  ? 32  ILE A CG1  1 
ATOM   446  C CG2  . ILE A 1 34  ? 36.83500 36.54100 5.64500   1.000 43.49000  ? 32  ILE A CG2  1 
ATOM   447  C CD1  . ILE A 1 34  ? 35.36500 36.37900 8.39800   1.000 36.59000  ? 32  ILE A CD1  1 
ATOM   448  H H    . ILE A 1 34  ? 35.65200 36.00500 3.48200   1.000 45.98000  ? 32  ILE A H    1 
ATOM   449  H HA   . ILE A 1 34  ? 33.65000 37.02500 4.78700   1.000 51.92000  ? 32  ILE A HA   1 
ATOM   450  H HB   . ILE A 1 34  ? 35.03600 35.59700 5.90900   1.000 46.79000  ? 32  ILE A HB   1 
ATOM   451  H HG12 . ILE A 1 34  ? 35.46500 38.04700 7.23400   1.000 53.57000  ? 32  ILE A HG12 1 
ATOM   452  H HG13 . ILE A 1 34  ? 34.03100 37.36600 7.21600   1.000 53.57000  ? 32  ILE A HG13 1 
ATOM   453  H HG21 . ILE A 1 34  ? 37.26000 36.91200 6.43400   1.000 52.04000  ? 32  ILE A HG21 1 
ATOM   454  H HG22 . ILE A 1 34  ? 37.14200 35.63300 5.50000   1.000 52.04000  ? 32  ILE A HG22 1 
ATOM   455  H HG23 . ILE A 1 34  ? 37.04500 37.08700 4.87300   1.000 52.04000  ? 32  ILE A HG23 1 
ATOM   456  H HD11 . ILE A 1 34  ? 35.09200 36.85400 9.19800   1.000 43.76000  ? 32  ILE A HD11 1 
ATOM   457  H HD12 . ILE A 1 34  ? 34.91000 35.52300 8.35000   1.000 43.76000  ? 32  ILE A HD12 1 
ATOM   458  H HD13 . ILE A 1 34  ? 36.32500 36.24300 8.40400   1.000 43.76000  ? 32  ILE A HD13 1 
ATOM   459  N N    . PRO A 1 35  ? 33.89200 39.53400 5.04500   1.000 41.95000  ? 33  PRO A N    1 
ATOM   460  C CA   . PRO A 1 35  ? 34.14500 40.98500 5.06300   1.000 40.29000  ? 33  PRO A CA   1 
ATOM   461  C C    . PRO A 1 35  ? 35.11500 41.34700 6.17700   1.000 40.38000  ? 33  PRO A C    1 
ATOM   462  O O    . PRO A 1 35  ? 34.86900 41.05500 7.34900   1.000 46.04000  ? 33  PRO A O    1 
ATOM   463  C CB   . PRO A 1 35  ? 32.75500 41.59700 5.29800   1.000 46.51000  ? 33  PRO A CB   1 
ATOM   464  C CG   . PRO A 1 35  ? 31.77500 40.48000 5.05600   1.000 44.01000  ? 33  PRO A CG   1 
ATOM   465  C CD   . PRO A 1 35  ? 32.49500 39.21500 5.40000   1.000 41.19000  ? 33  PRO A CD   1 
ATOM   466  H HA   . PRO A 1 35  ? 34.49700 41.28400 4.20900   1.000 48.21000  ? 33  PRO A HA   1 
ATOM   467  H HB2  . PRO A 1 35  ? 32.69000 41.91700 6.21100   1.000 55.67000  ? 33  PRO A HB2  1 
ATOM   468  H HB3  . PRO A 1 35  ? 32.60900 42.32200 4.67000   1.000 55.67000  ? 33  PRO A HB3  1 
ATOM   469  H HG2  . PRO A 1 35  ? 31.00200 40.59800 5.63000   1.000 52.67000  ? 33  PRO A HG2  1 
ATOM   470  H HG3  . PRO A 1 35  ? 31.51100 40.47700 4.12300   1.000 52.67000  ? 33  PRO A HG3  1 
ATOM   471  H HD2  . PRO A 1 35  ? 32.41800 39.02500 6.34800   1.000 49.28000  ? 33  PRO A HD2  1 
ATOM   472  H HD3  . PRO A 1 35  ? 32.15300 38.48800 4.85700   1.000 49.28000  ? 33  PRO A HD3  1 
ATOM   473  N N    . GLN A 1 36  ? 36.21900 41.99700 5.80400   1.000 41.18000  ? 34  GLN A N    1 
ATOM   474  C CA   . GLN A 1 36  ? 37.27600 42.33400 6.74800   1.000 42.68000  ? 34  GLN A CA   1 
ATOM   475  C C    . GLN A 1 36  ? 36.95400 43.54600 7.62100   1.000 46.87000  ? 34  GLN A C    1 
ATOM   476  O O    . GLN A 1 36  ? 37.68100 43.80300 8.58800   1.000 42.31000  ? 34  GLN A O    1 
ATOM   477  C CB   . GLN A 1 36  ? 38.58700 42.62300 6.00000   1.000 48.11000  ? 34  GLN A CB   1 
ATOM   478  C CG   . GLN A 1 36  ? 39.22800 41.43500 5.29500   1.000 54.03000  ? 34  GLN A CG   1 
ATOM   479  C CD   . GLN A 1 36  ? 39.40100 40.25000 6.20700   1.000 46.40000  ? 34  GLN A CD   1 
ATOM   480  O OE1  . GLN A 1 36  ? 38.46400 39.48400 6.41100   1.000 53.91000  ? 34  GLN A OE1  1 
ATOM   481  N NE2  . GLN A 1 36  ? 40.60300 40.09300 6.76600   1.000 40.30000  ? 34  GLN A NE2  1 
ATOM   482  H H    . GLN A 1 36  ? 36.37800 42.25500 4.99900   1.000 49.27000  ? 34  GLN A H    1 
ATOM   483  H HA   . GLN A 1 36  ? 37.42100 41.57900 7.33900   1.000 51.07000  ? 34  GLN A HA   1 
ATOM   484  H HB2  . GLN A 1 36  ? 38.41200 43.29800 5.32600   1.000 57.59000  ? 34  GLN A HB2  1 
ATOM   485  H HB3  . GLN A 1 36  ? 39.23400 42.96400 6.63700   1.000 57.59000  ? 34  GLN A HB3  1 
ATOM   486  H HG2  . GLN A 1 36  ? 38.66500 41.16400 4.55400   1.000 64.69000  ? 34  GLN A HG2  1 
ATOM   487  H HG3  . GLN A 1 36  ? 40.10400 41.69400 4.96900   1.000 64.69000  ? 34  GLN A HG3  1 
ATOM   488  H HE21 . GLN A 1 36  ? 41.23200 40.65400 6.59600   1.000 48.22000  ? 34  GLN A HE21 1 
ATOM   489  H HE22 . GLN A 1 36  ? 40.74800 39.43100 7.29500   1.000 48.22000  ? 34  GLN A HE22 1 
ATOM   490  N N    . SER A 1 37  ? 35.90600 44.30700 7.30300   1.000 46.14000  ? 35  SER A N    1 
ATOM   491  C CA   . SER A 1 37  ? 35.61900 45.55100 8.00900   1.000 44.35000  ? 35  SER A CA   1 
ATOM   492  C C    . SER A 1 37  ? 34.28900 45.52400 8.74800   1.000 51.44000  ? 35  SER A C    1 
ATOM   493  O O    . SER A 1 37  ? 33.87600 46.55400 9.29500   1.000 49.81000  ? 35  SER A O    1 
ATOM   494  C CB   . SER A 1 37  ? 35.64300 46.72600 7.02500   1.000 49.60000  ? 35  SER A CB   1 
ATOM   495  O OG   . SER A 1 37  ? 36.96100 46.95600 6.55300   1.000 55.32000  ? 35  SER A OG   1 
ATOM   496  H H    . SER A 1 37  ? 35.34400 44.12200 6.67800   1.000 55.22000  ? 35  SER A H    1 
ATOM   497  H HA   . SER A 1 37  ? 36.31400 45.70700 8.66600   1.000 53.07000  ? 35  SER A HA   1 
ATOM   498  H HB2  . SER A 1 37  ? 35.06900 46.51900 6.27200   1.000 59.37000  ? 35  SER A HB2  1 
ATOM   499  H HB3  . SER A 1 37  ? 35.32600 47.52400 7.47700   1.000 59.37000  ? 35  SER A HB3  1 
ATOM   500  H HG   . SER A 1 37  ? 36.96400 47.60100 6.01500   1.000 66.24000  ? 35  SER A HG   1 
ATOM   501  N N    . ALA A 1 38  ? 33.61900 44.37800 8.79600   1.000 47.87000  ? 36  ALA A N    1 
ATOM   502  C CA   . ALA A 1 38  ? 32.32100 44.29900 9.44800   1.000 48.56000  ? 36  ALA A CA   1 
ATOM   503  C C    . ALA A 1 38  ? 32.46800 44.37700 10.96100  1.000 46.83000  ? 36  ALA A C    1 
ATOM   504  O O    . ALA A 1 38  ? 33.39500 43.80800 11.54600  1.000 49.99000  ? 36  ALA A O    1 
ATOM   505  C CB   . ALA A 1 38  ? 31.61700 42.99800 9.06300   1.000 40.83000  ? 36  ALA A CB   1 
ATOM   506  H H    . ALA A 1 38  ? 33.89200 43.63500 8.46000   1.000 57.30000  ? 36  ALA A H    1 
ATOM   507  H HA   . ALA A 1 38  ? 31.77000 45.04200 9.15600   1.000 58.13000  ? 36  ALA A HA   1 
ATOM   508  H HB1  . ALA A 1 38  ? 30.75500 42.96200 9.50600   1.000 48.85000  ? 36  ALA A HB1  1 
ATOM   509  H HB2  . ALA A 1 38  ? 31.49600 42.97800 8.10100   1.000 48.85000  ? 36  ALA A HB2  1 
ATOM   510  H HB3  . ALA A 1 38  ? 32.16500 42.24800 9.34300   1.000 48.85000  ? 36  ALA A HB3  1 
ATOM   511  N N    . LYS A 1 39  ? 31.53100 45.08100 11.59500  1.000 52.48000  ? 37  LYS A N    1 
ATOM   512  C CA   . LYS A 1 39  ? 31.50000 45.20400 13.04800  1.000 51.62000  ? 37  LYS A CA   1 
ATOM   513  C C    . LYS A 1 39  ? 30.66300 44.12400 13.71400  1.000 48.22000  ? 37  LYS A C    1 
ATOM   514  O O    . LYS A 1 39  ? 30.78900 43.91400 14.92400  1.000 42.99000  ? 37  LYS A O    1 
ATOM   515  C CB   . LYS A 1 39  ? 30.96800 46.58500 13.43700  1.000 60.35000  ? 37  LYS A CB   1 
ATOM   516  C CG   . LYS A 1 39  ? 32.04600 47.66400 13.63600  1.000 69.87000  ? 37  LYS A CG   1 
ATOM   517  C CD   . LYS A 1 39  ? 33.18100 47.59700 12.61100  1.000 64.84000  ? 37  LYS A CD   1 
ATOM   518  C CE   . LYS A 1 39  ? 34.49700 48.14000 13.19300  1.000 63.27000  ? 37  LYS A CE   1 
ATOM   519  N NZ   . LYS A 1 39  ? 34.32600 49.44900 13.90200  1.000 76.34000  ? 37  LYS A NZ   1 
ATOM   520  H H    . LYS A 1 39  ? 30.89400 45.50100 11.19800  1.000 62.83000  ? 37  LYS A H    1 
ATOM   521  H HA   . LYS A 1 39  ? 32.40200 45.11700 13.39500  1.000 61.79000  ? 37  LYS A HA   1 
ATOM   522  H HB2  . LYS A 1 39  ? 30.37000 46.89400 12.73700  1.000 72.27000  ? 37  LYS A HB2  1 
ATOM   523  H HB3  . LYS A 1 39  ? 30.47900 46.50300 14.27000  1.000 72.27000  ? 37  LYS A HB3  1 
ATOM   524  H HG2  . LYS A 1 39  ? 31.63100 48.53800 13.56300  1.000 83.70000  ? 37  LYS A HG2  1 
ATOM   525  H HG3  . LYS A 1 39  ? 32.43700 47.55800 14.51800  1.000 83.70000  ? 37  LYS A HG3  1 
ATOM   526  H HD2  . LYS A 1 39  ? 33.35100 46.69200 12.32200  1.000 77.66000  ? 37  LYS A HD2  1 
ATOM   527  H HD3  . LYS A 1 39  ? 32.94500 48.14700 11.84700  1.000 77.66000  ? 37  LYS A HD3  1 
ATOM   528  H HE2  . LYS A 1 39  ? 34.86200 47.49700 13.82000  1.000 75.78000  ? 37  LYS A HE2  1 
ATOM   529  H HE3  . LYS A 1 39  ? 35.11100 48.28700 12.46400  1.000 75.78000  ? 37  LYS A HE3  1 
ATOM   530  H HZ1  . LYS A 1 39  ? 35.11600 49.74700 14.18300  1.000 91.46000  ? 37  LYS A HZ1  1 
ATOM   531  H HZ2  . LYS A 1 39  ? 33.97100 50.04900 13.35000  1.000 91.46000  ? 37  LYS A HZ2  1 
ATOM   532  H HZ3  . LYS A 1 39  ? 33.78900 49.34800 14.60300  1.000 91.46000  ? 37  LYS A HZ3  1 
ATOM   533  N N    . GLU A 1 40  ? 29.82000 43.43800 12.95600  1.000 47.51000  ? 38  GLU A N    1 
ATOM   534  C CA   . GLU A 1 40  ? 29.04200 42.33600 13.49800  1.000 47.75000  ? 38  GLU A CA   1 
ATOM   535  C C    . GLU A 1 40  ? 28.67700 41.41200 12.34800  1.000 41.34000  ? 38  GLU A C    1 
ATOM   536  O O    . GLU A 1 40  ? 28.68100 41.81000 11.18100  1.000 39.18000  ? 38  GLU A O    1 
ATOM   537  C CB   . GLU A 1 40  ? 27.78500 42.83100 14.22700  1.000 55.42000  ? 38  GLU A CB   1 
ATOM   538  C CG   . GLU A 1 40  ? 27.17800 44.11800 13.68300  1.000 59.90000  ? 38  GLU A CG   1 
ATOM   539  C CD   . GLU A 1 40  ? 25.91800 44.53000 14.43800  1.000 72.21000  ? 38  GLU A CD   1 
ATOM   540  O OE1  . GLU A 1 40  ? 26.03800 45.16800 15.50900  1.000 72.70000  ? 38  GLU A OE1  1 
ATOM   541  O OE2  . GLU A 1 40  ? 24.80800 44.20800 13.96100  1.000 75.68000  ? 38  GLU A OE2  1 
ATOM   542  H H    . GLU A 1 40  ? 29.67900 43.59100 12.12200  1.000 56.86000  ? 38  GLU A H    1 
ATOM   543  H HA   . GLU A 1 40  ? 29.58400 41.83900 14.12900  1.000 57.16000  ? 38  GLU A HA   1 
ATOM   544  H HB2  . GLU A 1 40  ? 27.10500 42.14100 14.17100  1.000 66.36000  ? 38  GLU A HB2  1 
ATOM   545  H HB3  . GLU A 1 40  ? 28.01200 42.98600 15.15700  1.000 66.36000  ? 38  GLU A HB3  1 
ATOM   546  H HG2  . GLU A 1 40  ? 27.82400 44.83600 13.76800  1.000 71.73000  ? 38  GLU A HG2  1 
ATOM   547  H HG3  . GLU A 1 40  ? 26.94200 43.98900 12.75100  1.000 71.73000  ? 38  GLU A HG3  1 
ATOM   548  N N    . PHE A 1 41  ? 28.39000 40.16300 12.69700  1.000 38.77000  ? 39  PHE A N    1 
ATOM   549  C CA   . PHE A 1 41  ? 27.85200 39.18100 11.76400  1.000 39.31000  ? 39  PHE A CA   1 
ATOM   550  C C    . PHE A 1 41  ? 26.57300 38.62800 12.37200  1.000 43.14000  ? 39  PHE A C    1 
ATOM   551  O O    . PHE A 1 41  ? 26.59000 38.13100 13.50500  1.000 44.35000  ? 39  PHE A O    1 
ATOM   552  C CB   . PHE A 1 41  ? 28.84500 38.05300 11.49600  1.000 37.54000  ? 39  PHE A CB   1 
ATOM   553  C CG   . PHE A 1 41  ? 30.04700 38.48600 10.71200  1.000 39.78000  ? 39  PHE A CG   1 
ATOM   554  C CD1  . PHE A 1 41  ? 29.90600 39.26000 9.57200   1.000 40.33000  ? 39  PHE A CD1  1 
ATOM   555  C CD2  . PHE A 1 41  ? 31.32100 38.11200 11.11000  1.000 43.59000  ? 39  PHE A CD2  1 
ATOM   556  C CE1  . PHE A 1 41  ? 31.01700 39.65800 8.84400   1.000 37.16000  ? 39  PHE A CE1  1 
ATOM   557  C CE2  . PHE A 1 41  ? 32.43000 38.50500 10.38500  1.000 42.24000  ? 39  PHE A CE2  1 
ATOM   558  C CZ   . PHE A 1 41  ? 32.27400 39.28200 9.25500   1.000 42.03000  ? 39  PHE A CZ   1 
ATOM   559  H H    . PHE A 1 41  ? 28.50100 39.85300 13.49100  1.000 46.38000  ? 39  PHE A H    1 
ATOM   560  H HA   . PHE A 1 41  ? 27.62600 39.61200 10.92500  1.000 47.02000  ? 39  PHE A HA   1 
ATOM   561  H HB2  . PHE A 1 41  ? 29.15400 37.70100 12.34500  1.000 44.90000  ? 39  PHE A HB2  1 
ATOM   562  H HB3  . PHE A 1 41  ? 28.39700 37.35500 10.99400  1.000 44.90000  ? 39  PHE A HB3  1 
ATOM   563  H HD1  . PHE A 1 41  ? 29.05700 39.51700 9.29300   1.000 48.24000  ? 39  PHE A HD1  1 
ATOM   564  H HD2  . PHE A 1 41  ? 31.43000 37.59100 11.87200  1.000 52.16000  ? 39  PHE A HD2  1 
ATOM   565  H HE1  . PHE A 1 41  ? 30.91200 40.17900 8.08100   1.000 44.44000  ? 39  PHE A HE1  1 
ATOM   566  H HE2  . PHE A 1 41  ? 33.28100 38.25200 10.66300  1.000 50.54000  ? 39  PHE A HE2  1 
ATOM   567  H HZ   . PHE A 1 41  ? 33.02000 39.54700 8.76700   1.000 50.29000  ? 39  PHE A HZ   1 
ATOM   568  N N    . PHE A 1 42  ? 25.46800 38.72000 11.63100  1.000 41.63000  ? 40  PHE A N    1 
ATOM   569  C CA   . PHE A 1 42  ? 24.19000 38.18000 12.09000  1.000 43.28000  ? 40  PHE A CA   1 
ATOM   570  C C    . PHE A 1 42  ? 23.80600 38.75200 13.45400  1.000 42.26000  ? 40  PHE A C    1 
ATOM   571  O O    . PHE A 1 42  ? 23.31700 38.03700 14.33300  1.000 45.60000  ? 40  PHE A O    1 
ATOM   572  C CB   . PHE A 1 42  ? 24.23900 36.65200 12.14000  1.000 39.03000  ? 40  PHE A CB   1 
ATOM   573  C CG   . PHE A 1 42  ? 24.68100 36.01400 10.84900  1.000 41.61000  ? 40  PHE A CG   1 
ATOM   574  C CD1  . PHE A 1 42  ? 23.96800 36.22000 9.67900   1.000 42.00000  ? 40  PHE A CD1  1 
ATOM   575  C CD2  . PHE A 1 42  ? 25.80800 35.21200 10.80900  1.000 36.77000  ? 40  PHE A CD2  1 
ATOM   576  C CE1  . PHE A 1 42  ? 24.36600 35.63200 8.49300   1.000 45.28000  ? 40  PHE A CE1  1 
ATOM   577  C CE2  . PHE A 1 42  ? 26.21200 34.63100 9.63000   1.000 38.06000  ? 40  PHE A CE2  1 
ATOM   578  C CZ   . PHE A 1 42  ? 25.48900 34.83600 8.46900   1.000 41.93000  ? 40  PHE A CZ   1 
ATOM   579  H H    . PHE A 1 42  ? 25.43300 39.09200 10.85600  1.000 49.81000  ? 40  PHE A H    1 
ATOM   580  H HA   . PHE A 1 42  ? 23.50000 38.43300 11.45800  1.000 51.79000  ? 40  PHE A HA   1 
ATOM   581  H HB2  . PHE A 1 42  ? 24.86200 36.38200 12.83200  1.000 46.69000  ? 40  PHE A HB2  1 
ATOM   582  H HB3  . PHE A 1 42  ? 23.35200 36.31800 12.34800  1.000 46.69000  ? 40  PHE A HB3  1 
ATOM   583  H HD1  . PHE A 1 42  ? 23.20700 36.75400 9.69300   1.000 50.25000  ? 40  PHE A HD1  1 
ATOM   584  H HD2  . PHE A 1 42  ? 26.29700 35.06700 11.58600  1.000 43.98000  ? 40  PHE A HD2  1 
ATOM   585  H HE1  . PHE A 1 42  ? 23.88000 35.77600 7.71400   1.000 54.19000  ? 40  PHE A HE1  1 
ATOM   586  H HE2  . PHE A 1 42  ? 26.97000 34.09200 9.61500   1.000 45.53000  ? 40  PHE A HE2  1 
ATOM   587  H HZ   . PHE A 1 42  ? 25.76500 34.44200 7.67300   1.000 50.17000  ? 40  PHE A HZ   1 
ATOM   588  N N    . GLY A 1 43  ? 24.03700 40.05400 13.63000  1.000 47.55000  ? 41  GLY A N    1 
ATOM   589  C CA   . GLY A 1 43  ? 23.67900 40.74900 14.84600  1.000 48.56000  ? 41  GLY A CA   1 
ATOM   590  C C    . GLY A 1 43  ? 24.63800 40.58600 16.00000  1.000 50.12000  ? 41  GLY A C    1 
ATOM   591  O O    . GLY A 1 43  ? 24.52700 41.33000 16.98400  1.000 59.10000  ? 41  GLY A O    1 
ATOM   592  H H    . GLY A 1 43  ? 24.40800 40.56000 13.04100  1.000 56.92000  ? 41  GLY A H    1 
ATOM   593  H HA2  . GLY A 1 43  ? 23.60600 41.69700 14.65300  1.000 58.13000  ? 41  GLY A HA2  1 
ATOM   594  H HA3  . GLY A 1 43  ? 22.80900 40.43700 15.13900  1.000 58.13000  ? 41  GLY A HA3  1 
ATOM   595  N N    . VAL A 1 44  ? 25.57800 39.65300 15.91900  1.000 47.61000  ? 42  VAL A N    1 
ATOM   596  C CA   . VAL A 1 44  ? 26.50900 39.38900 17.01500  1.000 38.56000  ? 42  VAL A CA   1 
ATOM   597  C C    . VAL A 1 44  ? 27.74300 40.26200 16.82900  1.000 51.04000  ? 42  VAL A C    1 
ATOM   598  O O    . VAL A 1 44  ? 28.32100 40.28900 15.73300  1.000 49.09000  ? 42  VAL A O    1 
ATOM   599  C CB   . VAL A 1 44  ? 26.88300 37.90000 17.07200  1.000 44.81000  ? 42  VAL A CB   1 
ATOM   600  C CG1  . VAL A 1 44  ? 27.97500 37.66500 18.10600  1.000 46.37000  ? 42  VAL A CG1  1 
ATOM   601  C CG2  . VAL A 1 44  ? 25.65400 37.05500 17.37600  1.000 47.06000  ? 42  VAL A CG2  1 
ATOM   602  H H    . VAL A 1 44  ? 25.70200 39.15100 15.23200  1.000 56.99000  ? 42  VAL A H    1 
ATOM   603  H HA   . VAL A 1 44  ? 26.07500 39.61400 17.85000  1.000 46.12000  ? 42  VAL A HA   1 
ATOM   604  H HB   . VAL A 1 44  ? 27.22600 37.62800 16.20700  1.000 53.62000  ? 42  VAL A HB   1 
ATOM   605  H HG11 . VAL A 1 44  ? 28.02500 36.71600 18.29900  1.000 55.49000  ? 42  VAL A HG11 1 
ATOM   606  H HG12 . VAL A 1 44  ? 28.82300 37.97300 17.74900  1.000 55.49000  ? 42  VAL A HG12 1 
ATOM   607  H HG13 . VAL A 1 44  ? 27.75600 38.15500 18.91400  1.000 55.49000  ? 42  VAL A HG13 1 
ATOM   608  H HG21 . VAL A 1 44  ? 25.92900 36.13500 17.51600  1.000 56.32000  ? 42  VAL A HG21 1 
ATOM   609  H HG22 . VAL A 1 44  ? 25.22700 37.40100 18.17500  1.000 56.32000  ? 42  VAL A HG22 1 
ATOM   610  H HG23 . VAL A 1 44  ? 25.04200 37.10700 16.62500  1.000 56.32000  ? 42  VAL A HG23 1 
ATOM   611  N N    . PRO A 1 45  ? 28.18000 41.00000 17.85200  1.000 48.68000  ? 43  PRO A N    1 
ATOM   612  C CA   . PRO A 1 45  ? 29.41000 41.79100 17.70100  1.000 46.57000  ? 43  PRO A CA   1 
ATOM   613  C C    . PRO A 1 45  ? 30.60200 40.89500 17.40000  1.000 43.51000  ? 43  PRO A C    1 
ATOM   614  O O    . PRO A 1 45  ? 30.74500 39.80200 17.95300  1.000 44.65000  ? 43  PRO A O    1 
ATOM   615  C CB   . PRO A 1 45  ? 29.55600 42.49700 19.05600  1.000 48.82000  ? 43  PRO A CB   1 
ATOM   616  C CG   . PRO A 1 45  ? 28.16900 42.52200 19.62700  1.000 48.45000  ? 43  PRO A CG   1 
ATOM   617  C CD   . PRO A 1 45  ? 27.51500 41.24700 19.14800  1.000 56.20000  ? 43  PRO A CD   1 
ATOM   618  H HA   . PRO A 1 45  ? 29.30900 42.45200 16.99800  1.000 55.74000  ? 43  PRO A HA   1 
ATOM   619  H HB2  . PRO A 1 45  ? 30.15400 41.99000 19.62700  1.000 58.44000  ? 43  PRO A HB2  1 
ATOM   620  H HB3  . PRO A 1 45  ? 29.88900 43.39800 18.92200  1.000 58.44000  ? 43  PRO A HB3  1 
ATOM   621  H HG2  . PRO A 1 45  ? 28.21600 42.54000 20.59600  1.000 58.00000  ? 43  PRO A HG2  1 
ATOM   622  H HG3  . PRO A 1 45  ? 27.69300 43.29800 19.29300  1.000 58.00000  ? 43  PRO A HG3  1 
ATOM   623  H HD2  . PRO A 1 45  ? 27.69300 40.52100 19.76500  1.000 67.29000  ? 43  PRO A HD2  1 
ATOM   624  H HD3  . PRO A 1 45  ? 26.56300 41.38700 19.02300  1.000 67.29000  ? 43  PRO A HD3  1 
ATOM   625  N N    . ILE A 1 46  ? 31.47100 41.38300 16.51400  1.000 46.02000  ? 44  ILE A N    1 
ATOM   626  C CA   . ILE A 1 46  ? 32.55100 40.55600 15.98100  1.000 47.82000  ? 44  ILE A CA   1 
ATOM   627  C C    . ILE A 1 46  ? 33.47100 40.05600 17.08700  1.000 49.41000  ? 44  ILE A C    1 
ATOM   628  O O    . ILE A 1 46  ? 33.99900 38.93900 17.00700  1.000 42.93000  ? 44  ILE A O    1 
ATOM   629  C CB   . ILE A 1 46  ? 33.32600 41.35600 14.91000  1.000 45.84000  ? 44  ILE A CB   1 
ATOM   630  C CG1  . ILE A 1 46  ? 34.33600 40.46300 14.19700  1.000 47.61000  ? 44  ILE A CG1  1 
ATOM   631  C CG2  . ILE A 1 46  ? 34.00900 42.56800 15.53700  1.000 49.13000  ? 44  ILE A CG2  1 
ATOM   632  C CD1  . ILE A 1 46  ? 33.69600 39.48400 13.24600  1.000 48.84000  ? 44  ILE A CD1  1 
ATOM   633  H H    . ILE A 1 46  ? 31.45600 42.18700 16.20700  1.000 55.08000  ? 44  ILE A H    1 
ATOM   634  H HA   . ILE A 1 46  ? 32.16200 39.78000 15.54900  1.000 57.24000  ? 44  ILE A HA   1 
ATOM   635  H HB   . ILE A 1 46  ? 32.68800 41.67500 14.25300  1.000 54.86000  ? 44  ILE A HB   1 
ATOM   636  H HG12 . ILE A 1 46  ? 34.93700 41.02400 13.68200  1.000 56.99000  ? 44  ILE A HG12 1 
ATOM   637  H HG13 . ILE A 1 46  ? 34.84200 39.95800 14.85200  1.000 56.99000  ? 44  ILE A HG13 1 
ATOM   638  H HG21 . ILE A 1 46  ? 34.38600 43.11600 14.83100  1.000 58.80000  ? 44  ILE A HG21 1 
ATOM   639  H HG22 . ILE A 1 46  ? 33.35400 43.08000 16.03600  1.000 58.80000  ? 44  ILE A HG22 1 
ATOM   640  H HG23 . ILE A 1 46  ? 34.71400 42.26500 16.13000  1.000 58.80000  ? 44  ILE A HG23 1 
ATOM   641  H HD11 . ILE A 1 46  ? 34.39100 39.04500 12.73000  1.000 58.46000  ? 44  ILE A HD11 1 
ATOM   642  H HD12 . ILE A 1 46  ? 33.19800 38.82700 13.75600  1.000 58.46000  ? 44  ILE A HD12 1 
ATOM   643  H HD13 . ILE A 1 46  ? 33.10000 39.96700 12.65400  1.000 58.46000  ? 44  ILE A HD13 1 
ATOM   644  N N    . LYS A 1 47  ? 33.67400 40.86000 18.13700  1.000 45.87000  ? 45  LYS A N    1 
ATOM   645  C CA   . LYS A 1 47  ? 34.58700 40.45900 19.20200  1.000 47.51000  ? 45  LYS A CA   1 
ATOM   646  C C    . LYS A 1 47  ? 34.12800 39.17900 19.88700  1.000 50.12000  ? 45  LYS A C    1 
ATOM   647  O O    . LYS A 1 47  ? 34.95800 38.41200 20.38800  1.000 44.24000  ? 45  LYS A O    1 
ATOM   648  C CB   . LYS A 1 47  ? 34.72200 41.58500 20.22700  1.000 52.76000  ? 45  LYS A CB   1 
ATOM   649  C CG   . LYS A 1 47  ? 36.15900 41.98700 20.53500  1.000 64.14000  ? 45  LYS A CG   1 
ATOM   650  C CD   . LYS A 1 47  ? 36.93700 40.86000 21.21700  1.000 70.88000  ? 45  LYS A CD   1 
ATOM   651  C CE   . LYS A 1 47  ? 38.36600 41.28800 21.55400  1.000 70.50000  ? 45  LYS A CE   1 
ATOM   652  N NZ   . LYS A 1 47  ? 39.29400 40.12600 21.69900  1.000 76.64000  ? 45  LYS A NZ   1 
ATOM   653  H H    . LYS A 1 47  ? 33.30000 41.62600 18.25000  1.000 54.90000  ? 45  LYS A H    1 
ATOM   654  H HA   . LYS A 1 47  ? 35.46300 40.29600 18.82000  1.000 56.86000  ? 45  LYS A HA   1 
ATOM   655  H HB2  . LYS A 1 47  ? 34.26300 42.37100 19.89300  1.000 63.16000  ? 45  LYS A HB2  1 
ATOM   656  H HB3  . LYS A 1 47  ? 34.31300 41.29800 21.05800  1.000 63.16000  ? 45  LYS A HB3  1 
ATOM   657  H HG2  . LYS A 1 47  ? 36.61200 42.20800 19.70600  1.000 76.82000  ? 45  LYS A HG2  1 
ATOM   658  H HG3  . LYS A 1 47  ? 36.15500 42.75300 21.12900  1.000 76.82000  ? 45  LYS A HG3  1 
ATOM   659  H HD2  . LYS A 1 47  ? 36.48900 40.61700 22.04300  1.000 84.90000  ? 45  LYS A HD2  1 
ATOM   660  H HD3  . LYS A 1 47  ? 36.98200 40.09500 20.62200  1.000 84.90000  ? 45  LYS A HD3  1 
ATOM   661  H HE2  . LYS A 1 47  ? 38.70300 41.85500 20.84400  1.000 84.45000  ? 45  LYS A HE2  1 
ATOM   662  H HE3  . LYS A 1 47  ? 38.36000 41.77500 22.39400  1.000 84.45000  ? 45  LYS A HE3  1 
ATOM   663  H HZ1  . LYS A 1 47  ? 40.11300 40.41400 21.89500  1.000 91.82000  ? 45  LYS A HZ1  1 
ATOM   664  H HZ2  . LYS A 1 47  ? 39.01200 39.59100 22.35200  1.000 91.82000  ? 45  LYS A HZ2  1 
ATOM   665  H HZ3  . LYS A 1 47  ? 39.32500 39.66400 20.93900  1.000 91.82000  ? 45  LYS A HZ3  1 
ATOM   666  N N    . GLN A 1 48  ? 32.81500 38.93700 19.92900  1.000 44.64000  ? 46  GLN A N    1 
ATOM   667  C CA   . GLN A 1 48  ? 32.29200 37.73800 20.56300  1.000 42.08000  ? 46  GLN A CA   1 
ATOM   668  C C    . GLN A 1 48  ? 32.36500 36.51300 19.65800  1.000 46.05000  ? 46  GLN A C    1 
ATOM   669  O O    . GLN A 1 48  ? 32.04300 35.40600 20.10900  1.000 44.68000  ? 46  GLN A O    1 
ATOM   670  C CB   . GLN A 1 48  ? 30.83800 37.96100 20.99400  1.000 53.03000  ? 46  GLN A CB   1 
ATOM   671  C CG   . GLN A 1 48  ? 30.67400 38.76900 22.27700  1.000 56.42000  ? 46  GLN A CG   1 
ATOM   672  C CD   . GLN A 1 48  ? 29.22600 39.15800 22.54400  1.000 63.26000  ? 46  GLN A CD   1 
ATOM   673  O OE1  . GLN A 1 48  ? 28.33800 38.30000 22.63200  1.000 58.60000  ? 46  GLN A OE1  1 
ATOM   674  N NE2  . GLN A 1 48  ? 28.98200 40.45700 22.67200  1.000 68.73000  ? 46  GLN A NE2  1 
ATOM   675  H H    . GLN A 1 48  ? 32.21200 39.45300 19.59700  1.000 53.42000  ? 46  GLN A H    1 
ATOM   676  H HA   . GLN A 1 48  ? 32.81400 37.55100 21.35900  1.000 50.35000  ? 46  GLN A HA   1 
ATOM   677  H HB2  . GLN A 1 48  ? 30.37300 38.43300 20.28600  1.000 63.49000  ? 46  GLN A HB2  1 
ATOM   678  H HB3  . GLN A 1 48  ? 30.42500 37.09700 21.13700  1.000 63.49000  ? 46  GLN A HB3  1 
ATOM   679  H HG2  . GLN A 1 48  ? 30.98500 38.23700 23.02700  1.000 67.55000  ? 46  GLN A HG2  1 
ATOM   680  H HG3  . GLN A 1 48  ? 31.19600 39.58300 22.20700  1.000 67.55000  ? 46  GLN A HG3  1 
ATOM   681  H HE21 . GLN A 1 48  ? 29.62500 41.02400 22.60400  1.000 82.33000  ? 46  GLN A HE21 1 
ATOM   682  H HE22 . GLN A 1 48  ? 28.18100 40.73100 22.82400  1.000 82.33000  ? 46  GLN A HE22 1 
ATOM   683  N N    . ILE A 1 49  ? 32.77500 36.67700 18.40200  1.000 42.93000  ? 47  ILE A N    1 
ATOM   684  C CA   . ILE A 1 49  ? 32.82200 35.58100 17.44100  1.000 43.11000  ? 47  ILE A CA   1 
ATOM   685  C C    . ILE A 1 49  ? 34.24000 35.03400 17.39800  1.000 41.70000  ? 47  ILE A C    1 
ATOM   686  O O    . ILE A 1 49  ? 35.20200 35.79500 17.22700  1.000 40.92000  ? 47  ILE A O    1 
ATOM   687  C CB   . ILE A 1 49  ? 32.36300 36.04100 16.04700  1.000 44.77000  ? 47  ILE A CB   1 
ATOM   688  C CG1  . ILE A 1 49  ? 30.92800 36.56900 16.12000  1.000 46.02000  ? 47  ILE A CG1  1 
ATOM   689  C CG2  . ILE A 1 49  ? 32.47000 34.88700 15.04900  1.000 36.54000  ? 47  ILE A CG2  1 
ATOM   690  C CD1  . ILE A 1 49  ? 30.46400 37.28600 14.87500  1.000 45.37000  ? 47  ILE A CD1  1 
ATOM   691  H H    . ILE A 1 49  ? 33.03600 37.42900 18.07600  1.000 51.36000  ? 47  ILE A H    1 
ATOM   692  H HA   . ILE A 1 49  ? 32.23100 34.87000 17.73400  1.000 51.59000  ? 47  ILE A HA   1 
ATOM   693  H HB   . ILE A 1 49  ? 32.94300 36.76000 15.75100  1.000 53.57000  ? 47  ILE A HB   1 
ATOM   694  H HG12 . ILE A 1 49  ? 30.32900 35.82100 16.26900  1.000 55.08000  ? 47  ILE A HG12 1 
ATOM   695  H HG13 . ILE A 1 49  ? 30.86000 37.19300 16.85800  1.000 55.08000  ? 47  ILE A HG13 1 
ATOM   696  H HG21 . ILE A 1 49  ? 32.02800 35.13900 14.22300  1.000 43.71000  ? 47  ILE A HG21 1 
ATOM   697  H HG22 . ILE A 1 49  ? 33.40600 34.70100 14.87700  1.000 43.71000  ? 47  ILE A HG22 1 
ATOM   698  H HG23 . ILE A 1 49  ? 32.04000 34.10400 15.42700  1.000 43.71000  ? 47  ILE A HG23 1 
ATOM   699  H HD11 . ILE A 1 49  ? 29.62400 37.73300 15.06300  1.000 54.29000  ? 47  ILE A HD11 1 
ATOM   700  H HD12 . ILE A 1 49  ? 31.13600 37.93800 14.61900  1.000 54.29000  ? 47  ILE A HD12 1 
ATOM   701  H HD13 . ILE A 1 49  ? 30.34400 36.63900 14.16300  1.000 54.29000  ? 47  ILE A HD13 1 
ATOM   702  N N    . GLN A 1 50  ? 34.36900 33.71800 17.55900  1.000 38.75000  ? 48  GLN A N    1 
ATOM   703  C CA   . GLN A 1 50  ? 35.66000 33.04000 17.59400  1.000 36.34000  ? 48  GLN A CA   1 
ATOM   704  C C    . GLN A 1 50  ? 35.95200 32.49700 16.20100  1.000 40.09000  ? 48  GLN A C    1 
ATOM   705  O O    . GLN A 1 50  ? 35.33200 31.52400 15.76400  1.000 38.82000  ? 48  GLN A O    1 
ATOM   706  C CB   . GLN A 1 50  ? 35.62100 31.94900 18.66100  1.000 48.41000  ? 48  GLN A CB   1 
ATOM   707  C CG   . GLN A 1 50  ? 36.93000 31.19700 18.86400  1.000 70.68000  ? 48  GLN A CG   1 
ATOM   708  C CD   . GLN A 1 50  ? 36.75600 29.95000 19.72300  1.000 73.77000  ? 48  GLN A CD   1 
ATOM   709  O OE1  . GLN A 1 50  ? 36.04400 29.96700 20.73000  1.000 70.63000  ? 48  GLN A OE1  1 
ATOM   710  N NE2  . GLN A 1 50  ? 37.40300 28.85600 19.32100  1.000 75.58000  ? 48  GLN A NE2  1 
ATOM   711  H H    . GLN A 1 50  ? 33.70200 33.18300 17.65200  1.000 46.36000  ? 48  GLN A H    1 
ATOM   712  H HA   . GLN A 1 50  ? 36.35400 33.67400 17.82800  1.000 43.46000  ? 48  GLN A HA   1 
ATOM   713  H HB2  . GLN A 1 50  ? 35.38500 32.35700 19.51000  1.000 57.95000  ? 48  GLN A HB2  1 
ATOM   714  H HB3  . GLN A 1 50  ? 34.94500 31.29900 18.41400  1.000 57.95000  ? 48  GLN A HB3  1 
ATOM   715  H HG2  . GLN A 1 50  ? 37.27600 30.92000 18.00100  1.000 84.67000  ? 48  GLN A HG2  1 
ATOM   716  H HG3  . GLN A 1 50  ? 37.56600 31.78100 19.30600  1.000 84.67000  ? 48  GLN A HG3  1 
ATOM   717  H HE21 . GLN A 1 50  ? 37.88200 28.88200 18.61900  1.000 90.55000  ? 48  GLN A HE21 1 
ATOM   718  H HE22 . GLN A 1 50  ? 37.33600 28.12600 19.77100  1.000 90.55000  ? 48  GLN A HE22 1 
ATOM   719  N N    . ILE A 1 51  ? 36.91100 33.11500 15.51400  1.000 40.89000  ? 49  ILE A N    1 
ATOM   720  C CA   . ILE A 1 51  ? 37.19600 32.82300 14.11300  1.000 39.32000  ? 49  ILE A CA   1 
ATOM   721  C C    . ILE A 1 51  ? 38.51600 32.07300 14.01200  1.000 41.22000  ? 49  ILE A C    1 
ATOM   722  O O    . ILE A 1 51  ? 39.48400 32.38500 14.71600  1.000 37.47000  ? 49  ILE A O    1 
ATOM   723  C CB   . ILE A 1 51  ? 37.21300 34.12100 13.27600  1.000 34.59000  ? 49  ILE A CB   1 
ATOM   724  C CG1  . ILE A 1 51  ? 35.88300 34.86300 13.45300  1.000 37.45000  ? 49  ILE A CG1  1 
ATOM   725  C CG2  . ILE A 1 51  ? 37.46600 33.81500 11.80900  1.000 34.03000  ? 49  ILE A CG2  1 
ATOM   726  C CD1  . ILE A 1 51  ? 35.74900 36.11700 12.62900  1.000 41.84000  ? 49  ILE A CD1  1 
ATOM   727  H H    . ILE A 1 51  ? 37.42100 33.72200 15.84800  1.000 48.93000  ? 49  ILE A H    1 
ATOM   728  H HA   . ILE A 1 51  ? 36.49800 32.25000 13.76000  1.000 47.03000  ? 49  ILE A HA   1 
ATOM   729  H HB   . ILE A 1 51  ? 37.92900 34.68900 13.60000  1.000 41.36000  ? 49  ILE A HB   1 
ATOM   730  H HG12 . ILE A 1 51  ? 35.16000 34.26700 13.20700  1.000 44.79000  ? 49  ILE A HG12 1 
ATOM   731  H HG13 . ILE A 1 51  ? 35.79100 35.11800 14.38400  1.000 44.79000  ? 49  ILE A HG13 1 
ATOM   732  H HG21 . ILE A 1 51  ? 37.51800 34.64700 11.31300  1.000 40.69000  ? 49  ILE A HG21 1 
ATOM   733  H HG22 . ILE A 1 51  ? 38.30300 33.33300 11.72000  1.000 40.69000  ? 49  ILE A HG22 1 
ATOM   734  H HG23 . ILE A 1 51  ? 36.73600 33.27300 11.47000  1.000 40.69000  ? 49  ILE A HG23 1 
ATOM   735  H HD11 . ILE A 1 51  ? 34.97900 36.61800 12.94100  1.000 50.06000  ? 49  ILE A HD11 1 
ATOM   736  H HD12 . ILE A 1 51  ? 36.55300 36.64900 12.73200  1.000 50.06000  ? 49  ILE A HD12 1 
ATOM   737  H HD13 . ILE A 1 51  ? 35.63100 35.87400 11.69800  1.000 50.06000  ? 49  ILE A HD13 1 
ATOM   738  N N    . HIS A 1 52  ? 38.55800 31.07400 13.13400  1.000 36.67000  ? 50  HIS A N    1 
ATOM   739  C CA   . HIS A 1 52  ? 39.78300 30.28700 12.86200  1.000 36.73000  ? 50  HIS A CA   1 
ATOM   740  C C    . HIS A 1 52  ? 40.01700 30.33400 11.35500  1.000 40.09000  ? 50  HIS A C    1 
ATOM   741  O O    . HIS A 1 52  ? 39.03600 30.42700 10.62300  1.000 34.30000  ? 50  HIS A O    1 
ATOM   742  C CB   . HIS A 1 52  ? 39.64300 28.85500 13.37000  1.000 47.86000  ? 50  HIS A CB   1 
ATOM   743  C CG   . HIS A 1 52  ? 39.63400 28.73400 14.85200  1.000 59.59000  ? 50  HIS A CG   1 
ATOM   744  N ND1  . HIS A 1 52  ? 40.64600 28.11400 15.55100  1.000 59.05000  ? 50  HIS A ND1  1 
ATOM   745  C CD2  . HIS A 1 52  ? 38.75000 29.14600 15.76100  1.000 62.61000  ? 50  HIS A CD2  1 
ATOM   746  C CE1  . HIS A 1 52  ? 40.36600 28.15900 16.84400  1.000 60.17000  ? 50  HIS A CE1  1 
ATOM   747  N NE2  . HIS A 1 52  ? 39.22100 28.78100 16.99200  1.000 62.83000  ? 50  HIS A NE2  1 
ATOM   748  H H    . HIS A 1 52  ? 37.88000 30.81900 12.67000  1.000 43.86000  ? 50  HIS A H    1 
ATOM   749  H HA   . HIS A 1 52  ? 40.54100 30.69900 13.30600  1.000 43.93000  ? 50  HIS A HA   1 
ATOM   750  H HB2  . HIS A 1 52  ? 38.80900 28.49000 13.04200  1.000 57.28000  ? 50  HIS A HB2  1 
ATOM   751  H HB3  . HIS A 1 52  ? 40.38600 28.33000 13.03400  1.000 57.28000  ? 50  HIS A HB3  1 
ATOM   752  H HD1  . HIS A 1 52  ? 41.34600 27.75700 15.20300  1.000 70.72000  ? 50  HIS A HD1  1 
ATOM   753  H HD2  . HIS A 1 52  ? 37.95700 29.60000 15.58900  1.000 74.99000  ? 50  HIS A HD2  1 
ATOM   754  H HE1  . HIS A 1 52  ? 40.89100 27.81100 17.52800  1.000 72.06000  ? 50  HIS A HE1  1 
ATOM   755  N N    . LYS A 1 53  ? 41.27200 30.29500 10.92800  1.000 31.20000  ? 51  LYS A N    1 
ATOM   756  C CA   . LYS A 1 53  ? 41.62600 30.36000 9.49400   1.000 31.05000  ? 51  LYS A CA   1 
ATOM   757  C C    . LYS A 1 53  ? 42.70000 29.31400 9.17500   1.000 36.97000  ? 51  LYS A C    1 
ATOM   758  O O    . LYS A 1 53  ? 43.68300 29.24600 9.92600   1.000 37.20000  ? 51  LYS A O    1 
ATOM   759  C CB   . LYS A 1 53  ? 42.07400 31.78300 9.16100   1.000 32.02000  ? 51  LYS A CB   1 
ATOM   760  C CG   . LYS A 1 53  ? 40.97200 32.82300 9.11900   1.000 35.81000  ? 51  LYS A CG   1 
ATOM   761  C CD   . LYS A 1 53  ? 40.80900 33.47400 7.75600   1.000 52.41000  ? 51  LYS A CD   1 
ATOM   762  C CE   . LYS A 1 53  ? 39.52300 34.21000 7.66300   1.000 54.35000  ? 51  LYS A CE   1 
ATOM   763  N NZ   . LYS A 1 53  ? 39.68300 35.65800 7.53300   1.000 75.48000  ? 51  LYS A NZ   1 
ATOM   764  H H    . LYS A 1 53  ? 41.95400 30.23000 11.44800  1.000 37.30000  ? 51  LYS A H    1 
ATOM   765  H HA   . LYS A 1 53  ? 40.84100 30.15800 8.96200   1.000 37.12000  ? 51  LYS A HA   1 
ATOM   766  H HB2  . LYS A 1 53  ? 42.71400 32.06600 9.83100   1.000 38.28000  ? 51  LYS A HB2  1 
ATOM   767  H HB3  . LYS A 1 53  ? 42.50000 31.77500 8.29000   1.000 38.28000  ? 51  LYS A HB3  1 
ATOM   768  H HG2  . LYS A 1 53  ? 40.13400 32.39300 9.34900   1.000 42.83000  ? 51  LYS A HG2  1 
ATOM   769  H HG3  . LYS A 1 53  ? 41.17300 33.52000 9.76100   1.000 42.83000  ? 51  LYS A HG3  1 
ATOM   770  H HD2  . LYS A 1 53  ? 41.50100 34.09400 7.56100   1.000 62.75000  ? 51  LYS A HD2  1 
ATOM   771  H HD3  . LYS A 1 53  ? 40.79700 32.77800 7.08100   1.000 62.75000  ? 51  LYS A HD3  1 
ATOM   772  H HE2  . LYS A 1 53  ? 39.03300 33.89100 6.88900   1.000 65.07000  ? 51  LYS A HE2  1 
ATOM   773  H HE3  . LYS A 1 53  ? 39.01600 34.05100 8.47200   1.000 65.07000  ? 51  LYS A HE3  1 
ATOM   774  H HZ1  . LYS A 1 53  ? 40.14500 35.97600 8.22400   1.000 90.43000  ? 51  LYS A HZ1  1 
ATOM   775  H HZ2  . LYS A 1 53  ? 40.11800 35.85000 6.78100   1.000 90.43000  ? 51  LYS A HZ2  1 
ATOM   776  H HZ3  . LYS A 1 53  ? 38.88500 36.05100 7.51300   1.000 90.43000  ? 51  LYS A HZ3  1 
ATOM   777  N N    . SER A 1 54  ? 42.48000 28.49000 8.16000   1.000 39.17000  ? 52  SER A N    1 
ATOM   778  C CA   . SER A 1 54  ? 43.48700 27.52000 7.66600   1.000 39.59000  ? 52  SER A CA   1 
ATOM   779  C C    . SER A 1 54  ? 43.57800 27.76600 6.16400   1.000 45.39000  ? 52  SER A C    1 
ATOM   780  O O    . SER A 1 54  ? 42.86700 27.08800 5.43700   1.000 41.60000  ? 52  SER A O    1 
ATOM   781  C CB   . SER A 1 54  ? 43.15300 26.10800 7.98800   1.000 44.44000  ? 52  SER A CB   1 
ATOM   782  O OG   . SER A 1 54  ? 44.24300 25.25700 7.67400   1.000 44.72000  ? 52  SER A OG   1 
ATOM   783  H H    . SER A 1 54  ? 41.74100 28.46300 7.72200   1.000 46.85000  ? 52  SER A H    1 
ATOM   784  H HA   . SER A 1 54  ? 44.34800 27.72400 8.06000   1.000 47.36000  ? 52  SER A HA   1 
ATOM   785  H HB2  . SER A 1 54  ? 42.96000 26.03700 8.93600   1.000 53.18000  ? 52  SER A HB2  1 
ATOM   786  H HB3  . SER A 1 54  ? 42.37900 25.83600 7.47100   1.000 53.18000  ? 52  SER A HB3  1 
ATOM   787  H HG   . SER A 1 54  ? 44.04900 24.46000 7.85900   1.000 53.51000  ? 52  SER A HG   1 
ATOM   788  N N    . GLY A 1 55  ? 44.39800 28.72000 5.73900   1.000 38.66000  ? 53  GLY A N    1 
ATOM   789  C CA   . GLY A 1 55  ? 44.49000 29.10200 4.34600   1.000 38.20000  ? 53  GLY A CA   1 
ATOM   790  C C    . GLY A 1 55  ? 43.22600 29.79100 3.88000   1.000 34.98000  ? 53  GLY A C    1 
ATOM   791  O O    . GLY A 1 55  ? 42.89100 30.88100 4.35700   1.000 32.83000  ? 53  GLY A O    1 
ATOM   792  H H    . GLY A 1 55  ? 44.92100 29.16800 6.25400   1.000 46.24000  ? 53  GLY A H    1 
ATOM   793  H HA2  . GLY A 1 55  ? 45.23800 29.70600 4.22100   1.000 45.69000  ? 53  GLY A HA2  1 
ATOM   794  H HA3  . GLY A 1 55  ? 44.63300 28.31300 3.80000   1.000 45.69000  ? 53  GLY A HA3  1 
ATOM   795  N N    . GLU A 1 56  ? 42.50400 29.15700 2.95900   1.000 34.50000  ? 54  GLU A N    1 
ATOM   796  C CA   . GLU A 1 56  ? 41.26500 29.70900 2.43300   1.000 33.57000  ? 54  GLU A CA   1 
ATOM   797  C C    . GLU A 1 56  ? 40.03300 29.18000 3.14800   1.000 33.81000  ? 54  GLU A C    1 
ATOM   798  O O    . GLU A 1 56  ? 38.91800 29.53700 2.76900   1.000 35.60000  ? 54  GLU A O    1 
ATOM   799  C CB   . GLU A 1 56  ? 41.15100 29.40800 0.93800   1.000 39.15000  ? 54  GLU A CB   1 
ATOM   800  C CG   . GLU A 1 56  ? 42.09100 30.23000 0.07900   1.000 42.98000  ? 54  GLU A CG   1 
ATOM   801  C CD   . GLU A 1 56  ? 41.77600 31.70900 0.13700   1.000 46.86000  ? 54  GLU A CD   1 
ATOM   802  O OE1  . GLU A 1 56  ? 40.57500 32.06600 0.10200   1.000 47.04000  ? 54  GLU A OE1  1 
ATOM   803  O OE2  . GLU A 1 56  ? 42.72700 32.51100 0.22000   1.000 48.00000  ? 54  GLU A OE2  1 
ATOM   804  H H    . GLU A 1 56  ? 42.71700 28.39600 2.62000   1.000 41.26000  ? 54  GLU A H    1 
ATOM   805  H HA   . GLU A 1 56  ? 41.27800 30.67200 2.54500   1.000 40.13000  ? 54  GLU A HA   1 
ATOM   806  H HB2  . GLU A 1 56  ? 41.34300 28.47000 0.78400   1.000 46.83000  ? 54  GLU A HB2  1 
ATOM   807  H HB3  . GLU A 1 56  ? 40.24800 29.61500 0.65500   1.000 46.83000  ? 54  GLU A HB3  1 
ATOM   808  H HG2  . GLU A 1 56  ? 42.99900 30.10300 0.39300   1.000 51.42000  ? 54  GLU A HG2  1 
ATOM   809  H HG3  . GLU A 1 56  ? 42.01300 29.94200 -0.84300  1.000 51.42000  ? 54  GLU A HG3  1 
ATOM   810  N N    . PHE A 1 57  ? 40.20900 28.32900 4.15900   1.000 33.62000  ? 55  PHE A N    1 
ATOM   811  C CA   . PHE A 1 57  ? 39.10300 27.81700 4.95900   1.000 29.65000  ? 55  PHE A CA   1 
ATOM   812  C C    . PHE A 1 57  ? 38.90400 28.71500 6.17400   1.000 32.73000  ? 55  PHE A C    1 
ATOM   813  O O    . PHE A 1 57  ? 39.83800 28.93900 6.94800   1.000 33.09000  ? 55  PHE A O    1 
ATOM   814  C CB   . PHE A 1 57  ? 39.37900 26.38000 5.40300   1.000 35.65000  ? 55  PHE A CB   1 
ATOM   815  C CG   . PHE A 1 57  ? 38.20000 25.71000 6.05500   1.000 41.54000  ? 55  PHE A CG   1 
ATOM   816  C CD1  . PHE A 1 57  ? 37.96500 25.85000 7.41600   1.000 37.68000  ? 55  PHE A CD1  1 
ATOM   817  C CD2  . PHE A 1 57  ? 37.32800 24.93000 5.30600   1.000 34.87000  ? 55  PHE A CD2  1 
ATOM   818  C CE1  . PHE A 1 57  ? 36.87900 25.23300 8.01400   1.000 41.93000  ? 55  PHE A CE1  1 
ATOM   819  C CE2  . PHE A 1 57  ? 36.24100 24.30800 5.90200   1.000 39.46000  ? 55  PHE A CE2  1 
ATOM   820  C CZ   . PHE A 1 57  ? 36.01900 24.45700 7.25200   1.000 39.89000  ? 55  PHE A CZ   1 
ATOM   821  H H    . PHE A 1 57  ? 40.97600 28.02800 4.40500   1.000 40.20000  ? 55  PHE A H    1 
ATOM   822  H HA   . PHE A 1 57  ? 38.28800 27.82500 4.43300   1.000 35.43000  ? 55  PHE A HA   1 
ATOM   823  H HB2  . PHE A 1 57  ? 39.62600 25.85500 4.62600   1.000 42.63000  ? 55  PHE A HB2  1 
ATOM   824  H HB3  . PHE A 1 57  ? 40.10900 26.38500 6.04200   1.000 42.63000  ? 55  PHE A HB3  1 
ATOM   825  H HD1  . PHE A 1 57  ? 38.54000 26.36900 7.93100   1.000 45.07000  ? 55  PHE A HD1  1 
ATOM   826  H HD2  . PHE A 1 57  ? 37.47400 24.82600 4.39400   1.000 41.70000  ? 55  PHE A HD2  1 
ATOM   827  H HE1  . PHE A 1 57  ? 36.73100 25.33400 8.92700   1.000 50.17000  ? 55  PHE A HE1  1 
ATOM   828  H HE2  . PHE A 1 57  ? 35.66300 23.78900 5.39000   1.000 47.21000  ? 55  PHE A HE2  1 
ATOM   829  H HZ   . PHE A 1 57  ? 35.29000 24.04200 7.65300   1.000 47.73000  ? 55  PHE A HZ   1 
ATOM   830  N N    . CYS A 1 58  ? 37.68300 29.21300 6.34100   1.000 32.99000  ? 56  CYS A N    1 
ATOM   831  C CA   . CYS A 1 58  ? 37.34500 30.16300 7.39700   1.000 31.33000  ? 56  CYS A CA   1 
ATOM   832  C C    . CYS A 1 58  ? 36.13200 29.63000 8.14000   1.000 37.24000  ? 56  CYS A C    1 
ATOM   833  O O    . CYS A 1 58  ? 35.08800 29.39700 7.52600   1.000 36.13000  ? 56  CYS A O    1 
ATOM   834  C CB   . CYS A 1 58  ? 37.06900 31.54600 6.79800   1.000 36.48000  ? 56  CYS A CB   1 
ATOM   835  S SG   . CYS A 1 58  ? 36.66400 32.85200 7.97500   1.000 37.90000  ? 56  CYS A SG   1 
ATOM   836  H H    . CYS A 1 58  ? 37.01400 29.00900 5.84100   1.000 39.44000  ? 56  CYS A H    1 
ATOM   837  H HA   . CYS A 1 58  ? 38.08300 30.23600 8.02200   1.000 37.45000  ? 56  CYS A HA   1 
ATOM   838  H HB2  . CYS A 1 58  ? 37.85900 31.83000 6.31100   1.000 43.63000  ? 56  CYS A HB2  1 
ATOM   839  H HB3  . CYS A 1 58  ? 36.32300 31.46900 6.18400   1.000 43.63000  ? 56  CYS A HB3  1 
ATOM   840  H HG   . CYS A 1 58  ? 36.47400 33.87400 7.37400   1.000 45.33000  ? 56  CYS A HG   1 
ATOM   841  N N    . ARG A 1 59  ? 36.26600 29.42000 9.45100   1.000 35.30000  ? 57  ARG A N    1 
ATOM   842  C CA   . ARG A 1 59  ? 35.16100 28.94900 10.28000  1.000 37.14000  ? 57  ARG A CA   1 
ATOM   843  C C    . ARG A 1 59  ? 34.88500 29.94900 11.39600  1.000 39.09000  ? 57  ARG A C    1 
ATOM   844  O O    . ARG A 1 59  ? 35.80900 30.47100 12.02600  1.000 36.22000  ? 57  ARG A O    1 
ATOM   845  C CB   . ARG A 1 59  ? 35.44100 27.54500 10.85500  1.000 46.49000  ? 57  ARG A CB   1 
ATOM   846  C CG   . ARG A 1 59  ? 36.28600 27.48900 12.11100  1.000 47.71000  ? 57  ARG A CG   1 
ATOM   847  C CD   . ARG A 1 59  ? 36.20300 26.10600 12.77600  1.000 53.72000  ? 57  ARG A CD   1 
ATOM   848  N NE   . ARG A 1 59  ? 37.04200 25.12200 12.09800  1.000 71.43000  ? 57  ARG A NE   1 
ATOM   849  C CZ   . ARG A 1 59  ? 36.78500 23.82000 12.03700  1.000 69.08000  ? 57  ARG A CZ   1 
ATOM   850  N NH1  . ARG A 1 59  ? 35.72100 23.29500 12.63100  1.000 66.07000  ? 57  ARG A NH1  1 
ATOM   851  N NH2  . ARG A 1 59  ? 37.61800 23.02500 11.36500  1.000 56.65000  ? 57  ARG A NH2  1 
ATOM   852  H H    . ARG A 1 59  ? 36.99700 29.54600 9.88600   1.000 42.22000  ? 57  ARG A H    1 
ATOM   853  H HA   . ARG A 1 59  ? 34.36100 28.88800 9.73600   1.000 44.43000  ? 57  ARG A HA   1 
ATOM   854  H HB2  . ARG A 1 59  ? 34.59000 27.12700 11.06000  1.000 55.64000  ? 57  ARG A HB2  1 
ATOM   855  H HB3  . ARG A 1 59  ? 35.90100 27.02500 10.17700  1.000 55.64000  ? 57  ARG A HB3  1 
ATOM   856  H HG2  . ARG A 1 59  ? 37.21000 27.65500 11.87500  1.000 57.10000  ? 57  ARG A HG2  1 
ATOM   857  H HG3  . ARG A 1 59  ? 35.98000 28.14000 12.75900  1.000 57.10000  ? 57  ARG A HG3  1 
ATOM   858  H HD2  . ARG A 1 59  ? 36.50200 26.17700 13.69600  1.000 64.32000  ? 57  ARG A HD2  1 
ATOM   859  H HD3  . ARG A 1 59  ? 35.28400 25.79900 12.74600  1.000 64.32000  ? 57  ARG A HD3  1 
ATOM   860  H HE   . ARG A 1 59  ? 37.67000 25.42300 11.59500  1.000 85.57000  ? 57  ARG A HE   1 
ATOM   861  H HH11 . ARG A 1 59  ? 35.17600 23.79600 13.06800  1.000 79.13000  ? 57  ARG A HH11 1 
ATOM   862  H HH12 . ARG A 1 59  ? 35.57600 22.44900 12.57800  1.000 79.13000  ? 57  ARG A HH12 1 
ATOM   863  H HH21 . ARG A 1 59  ? 38.31000 23.35700 10.97800  1.000 67.84000  ? 57  ARG A HH21 1 
ATOM   864  H HH22 . ARG A 1 59  ? 37.46200 22.18000 11.32000  1.000 67.84000  ? 57  ARG A HH22 1 
ATOM   865  N N    . LEU A 1 60  ? 33.60500 30.21200 11.62800  1.000 40.10000  ? 58  LEU A N    1 
ATOM   866  C CA   . LEU A 1 60  ? 33.15300 31.19300 12.60500  1.000 31.58000  ? 58  LEU A CA   1 
ATOM   867  C C    . LEU A 1 60  ? 32.31600 30.47100 13.65300  1.000 39.51000  ? 58  LEU A C    1 
ATOM   868  O O    . LEU A 1 60  ? 31.33200 29.80600 13.31200  1.000 35.29000  ? 58  LEU A O    1 
ATOM   869  C CB   . LEU A 1 60  ? 32.33800 32.30100 11.92600  1.000 40.61000  ? 58  LEU A CB   1 
ATOM   870  C CG   . LEU A 1 60  ? 33.09100 33.32700 11.07800  1.000 36.67000  ? 58  LEU A CG   1 
ATOM   871  C CD1  . LEU A 1 60  ? 33.67700 32.70500 9.81700   1.000 40.53000  ? 58  LEU A CD1  1 
ATOM   872  C CD2  . LEU A 1 60  ? 32.17600 34.48000 10.69500  1.000 41.37000  ? 58  LEU A CD2  1 
ATOM   873  H H    . LEU A 1 60  ? 32.95800 29.82100 11.21800  1.000 47.98000  ? 58  LEU A H    1 
ATOM   874  H HA   . LEU A 1 60  ? 33.91800 31.59600 13.04500  1.000 37.75000  ? 58  LEU A HA   1 
ATOM   875  H HB2  . LEU A 1 60  ? 31.68600 31.87800 11.34600  1.000 48.58000  ? 58  LEU A HB2  1 
ATOM   876  H HB3  . LEU A 1 60  ? 31.87200 32.79500 12.61900  1.000 48.58000  ? 58  LEU A HB3  1 
ATOM   877  H HG   . LEU A 1 60  ? 33.82400 33.68900 11.59700  1.000 43.86000  ? 58  LEU A HG   1 
ATOM   878  H HD11 . LEU A 1 60  ? 33.86400 33.40900 9.17700   1.000 48.49000  ? 58  LEU A HD11 1 
ATOM   879  H HD12 . LEU A 1 60  ? 34.49600 32.24100 10.04400  1.000 48.49000  ? 58  LEU A HD12 1 
ATOM   880  H HD13 . LEU A 1 60  ? 33.03400 32.08400 9.44400   1.000 48.49000  ? 58  LEU A HD13 1 
ATOM   881  H HD21 . LEU A 1 60  ? 32.68500 35.13000 10.18500  1.000 49.49000  ? 58  LEU A HD21 1 
ATOM   882  H HD22 . LEU A 1 60  ? 31.44500 34.13800 10.15900  1.000 49.49000  ? 58  LEU A HD22 1 
ATOM   883  H HD23 . LEU A 1 60  ? 31.83100 34.89100 11.50300  1.000 49.49000  ? 58  LEU A HD23 1 
ATOM   884  N N    . ARG A 1 61  ? 32.70700 30.60000 14.91700  1.000 41.91000  ? 59  ARG A N    1 
ATOM   885  C CA   . ARG A 1 61  ? 31.99100 30.00300 16.04000  1.000 38.57000  ? 59  ARG A CA   1 
ATOM   886  C C    . ARG A 1 61  ? 31.28000 31.11200 16.80300  1.000 46.05000  ? 59  ARG A C    1 
ATOM   887  O O    . ARG A 1 61  ? 31.93100 31.99000 17.38100  1.000 44.40000  ? 59  ARG A O    1 
ATOM   888  C CB   . ARG A 1 61  ? 32.94400 29.23400 16.95900  1.000 47.52000  ? 59  ARG A CB   1 
ATOM   889  C CG   . ARG A 1 61  ? 32.32700 28.75500 18.27200  1.000 43.37000  ? 59  ARG A CG   1 
ATOM   890  C CD   . ARG A 1 61  ? 31.30100 27.64300 18.05600  1.000 50.09000  ? 59  ARG A CD   1 
ATOM   891  N NE   . ARG A 1 61  ? 31.91900 26.38600 17.63900  1.000 52.88000  ? 59  ARG A NE   1 
ATOM   892  C CZ   . ARG A 1 61  ? 31.24800 25.28300 17.33800  1.000 43.03000  ? 59  ARG A CZ   1 
ATOM   893  N NH1  . ARG A 1 61  ? 29.93000 25.23700 17.40800  1.000 49.74000  ? 59  ARG A NH1  1 
ATOM   894  N NH2  . ARG A 1 61  ? 31.91700 24.19900 16.95500  1.000 53.19000  ? 59  ARG A NH2  1 
ATOM   895  H H    . ARG A 1 61  ? 33.40500 31.04200 15.15600  1.000 50.14000  ? 59  ARG A H    1 
ATOM   896  H HA   . ARG A 1 61  ? 31.32300 29.38400 15.70600  1.000 46.13000  ? 59  ARG A HA   1 
ATOM   897  H HB2  . ARG A 1 61  ? 33.26700 28.45200 16.48500  1.000 56.88000  ? 59  ARG A HB2  1 
ATOM   898  H HB3  . ARG A 1 61  ? 33.69200 29.81100 17.18000  1.000 56.88000  ? 59  ARG A HB3  1 
ATOM   899  H HG2  . ARG A 1 61  ? 33.03200 28.40100 18.83700  1.000 51.89000  ? 59  ARG A HG2  1 
ATOM   900  H HG3  . ARG A 1 61  ? 31.88700 29.49300 18.72100  1.000 51.89000  ? 59  ARG A HG3  1 
ATOM   901  H HD2  . ARG A 1 61  ? 30.82700 27.48400 18.88600  1.000 59.96000  ? 59  ARG A HD2  1 
ATOM   902  H HD3  . ARG A 1 61  ? 30.67700 27.91500 17.36400  1.000 59.96000  ? 59  ARG A HD3  1 
ATOM   903  H HE   . ARG A 1 61  ? 32.77700 26.36000 17.58700  1.000 63.30000  ? 59  ARG A HE   1 
ATOM   904  H HH11 . ARG A 1 61  ? 29.48600 25.93100 17.65300  1.000 59.54000  ? 59  ARG A HH11 1 
ATOM   905  H HH12 . ARG A 1 61  ? 29.51500 24.51200 17.20800  1.000 59.54000  ? 59  ARG A HH12 1 
ATOM   906  H HH21 . ARG A 1 61  ? 32.77500 24.21800 16.90600  1.000 63.68000  ? 59  ARG A HH21 1 
ATOM   907  H HH22 . ARG A 1 61  ? 31.49100 23.47800 16.75700  1.000 63.68000  ? 59  ARG A HH22 1 
ATOM   908  N N    . PHE A 1 62  ? 29.94300 31.07200 16.80300  1.000 47.38000  ? 60  PHE A N    1 
ATOM   909  C CA   . PHE A 1 62  ? 29.17300 32.11100 17.47900  1.000 43.20000  ? 60  PHE A CA   1 
ATOM   910  C C    . PHE A 1 62  ? 28.92200 31.73200 18.93400  1.000 40.42000  ? 60  PHE A C    1 
ATOM   911  O O    . PHE A 1 62  ? 28.83100 30.54600 19.27000  1.000 45.18000  ? 60  PHE A O    1 
ATOM   912  C CB   . PHE A 1 62  ? 27.85100 32.33400 16.75600  1.000 45.16000  ? 60  PHE A CB   1 
ATOM   913  C CG   . PHE A 1 62  ? 28.02100 32.96000 15.40800  1.000 44.63000  ? 60  PHE A CG   1 
ATOM   914  C CD1  . PHE A 1 62  ? 28.53100 32.22300 14.35300  1.000 41.32000  ? 60  PHE A CD1  1 
ATOM   915  C CD2  . PHE A 1 62  ? 27.72100 34.29600 15.20300  1.000 40.13000  ? 60  PHE A CD2  1 
ATOM   916  C CE1  . PHE A 1 62  ? 28.71200 32.80100 13.11900  1.000 39.78000  ? 60  PHE A CE1  1 
ATOM   917  C CE2  . PHE A 1 62  ? 27.90000 34.87700 13.96800  1.000 42.97000  ? 60  PHE A CE2  1 
ATOM   918  C CZ   . PHE A 1 62  ? 28.39700 34.13000 12.92400  1.000 38.38000  ? 60  PHE A CZ   1 
ATOM   919  H H    . PHE A 1 62  ? 29.46800 30.46200 16.42500  1.000 56.71000  ? 60  PHE A H    1 
ATOM   920  H HA   . PHE A 1 62  ? 29.67600 32.93800 17.45300  1.000 51.69000  ? 60  PHE A HA   1 
ATOM   921  H HB2  . PHE A 1 62  ? 27.41000 31.47900 16.63400  1.000 54.05000  ? 60  PHE A HB2  1 
ATOM   922  H HB3  . PHE A 1 62  ? 27.29400 32.92100 17.29100  1.000 54.05000  ? 60  PHE A HB3  1 
ATOM   923  H HD1  . PHE A 1 62  ? 28.74600 31.32700 14.47900  1.000 49.44000  ? 60  PHE A HD1  1 
ATOM   924  H HD2  . PHE A 1 62  ? 27.38600 34.80500 15.90600  1.000 48.00000  ? 60  PHE A HD2  1 
ATOM   925  H HE1  . PHE A 1 62  ? 29.04700 32.29500 12.41400  1.000 47.59000  ? 60  PHE A HE1  1 
ATOM   926  H HE2  . PHE A 1 62  ? 27.68700 35.77300 13.83900  1.000 51.42000  ? 60  PHE A HE2  1 
ATOM   927  H HZ   . PHE A 1 62  ? 28.51600 34.51900 12.08800  1.000 45.91000  ? 60  PHE A HZ   1 
ATOM   928  N N    . PRO A 1 63  ? 28.82900 32.72900 19.81900  1.000 45.33000  ? 61  PRO A N    1 
ATOM   929  C CA   . PRO A 1 63  ? 28.69300 32.41100 21.25200  1.000 46.15000  ? 61  PRO A CA   1 
ATOM   930  C C    . PRO A 1 63  ? 27.37000 31.75500 21.60800  1.000 49.57000  ? 61  PRO A C    1 
ATOM   931  O O    . PRO A 1 63  ? 27.30400 31.02500 22.60400  1.000 51.51000  ? 61  PRO A O    1 
ATOM   932  C CB   . PRO A 1 63  ? 28.84300 33.78100 21.93100  1.000 51.34000  ? 61  PRO A CB   1 
ATOM   933  C CG   . PRO A 1 63  ? 28.40000 34.76700 20.88800  1.000 56.89000  ? 61  PRO A CG   1 
ATOM   934  C CD   . PRO A 1 63  ? 28.83000 34.18300 19.56300  1.000 50.89000  ? 61  PRO A CD   1 
ATOM   935  H HA   . PRO A 1 63  ? 29.42000 31.83500 21.53600  1.000 55.23000  ? 61  PRO A HA   1 
ATOM   936  H HB2  . PRO A 1 63  ? 28.27100 33.82500 22.71300  1.000 61.46000  ? 61  PRO A HB2  1 
ATOM   937  H HB3  . PRO A 1 63  ? 29.77100 33.92900 22.17200  1.000 61.46000  ? 61  PRO A HB3  1 
ATOM   938  H HG2  . PRO A 1 63  ? 27.43500 34.86100 20.92100  1.000 68.12000  ? 61  PRO A HG2  1 
ATOM   939  H HG3  . PRO A 1 63  ? 28.83000 35.62000 21.04200  1.000 68.12000  ? 61  PRO A HG3  1 
ATOM   940  H HD2  . PRO A 1 63  ? 28.18900 34.40500 18.87100  1.000 60.92000  ? 61  PRO A HD2  1 
ATOM   941  H HD3  . PRO A 1 63  ? 29.72200 34.48600 19.33300  1.000 60.92000  ? 61  PRO A HD3  1 
ATOM   942  N N    . LYS A 1 64  ? 26.31900 31.99200 20.83100  1.000 48.11000  ? 62  LYS A N    1 
ATOM   943  C CA   . LYS A 1 64  ? 25.00000 31.43000 21.07100  1.000 52.63000  ? 62  LYS A CA   1 
ATOM   944  C C    . LYS A 1 64  ? 24.43600 30.89200 19.76500  1.000 56.76000  ? 62  LYS A C    1 
ATOM   945  O O    . LYS A 1 64  ? 24.79100 31.37800 18.68500  1.000 58.72000  ? 62  LYS A O    1 
ATOM   946  C CB   . LYS A 1 64  ? 24.05200 32.49100 21.64900  1.000 55.35000  ? 62  LYS A CB   1 
ATOM   947  C CG   . LYS A 1 64  ? 23.68600 33.60900 20.67000  1.000 64.99000  ? 62  LYS A CG   1 
ATOM   948  C CD   . LYS A 1 64  ? 23.89200 35.00000 21.27700  1.000 66.49000  ? 62  LYS A CD   1 
ATOM   949  C CE   . LYS A 1 64  ? 23.70600 36.10500 20.23900  1.000 59.07000  ? 62  LYS A CE   1 
ATOM   950  N NZ   . LYS A 1 64  ? 22.27200 36.28800 19.86800  1.000 69.20000  ? 62  LYS A NZ   1 
ATOM   951  H H    . LYS A 1 64  ? 26.34900 32.49400 20.13400  1.000 57.59000  ? 62  LYS A H    1 
ATOM   952  H HA   . LYS A 1 64  ? 25.07700 30.70600 21.70900  1.000 63.01000  ? 62  LYS A HA   1 
ATOM   953  H HB2  . LYS A 1 64  ? 23.22900 32.05600 21.92100  1.000 66.28000  ? 62  LYS A HB2  1 
ATOM   954  H HB3  . LYS A 1 64  ? 24.47600 32.90000 22.41900  1.000 66.28000  ? 62  LYS A HB3  1 
ATOM   955  H HG2  . LYS A 1 64  ? 24.24700 33.54400 19.88200  1.000 77.84000  ? 62  LYS A HG2  1 
ATOM   956  H HG3  . LYS A 1 64  ? 22.75200 33.52200 20.42200  1.000 77.84000  ? 62  LYS A HG3  1 
ATOM   957  H HD2  . LYS A 1 64  ? 23.24400 35.13800 21.98600  1.000 79.65000  ? 62  LYS A HD2  1 
ATOM   958  H HD3  . LYS A 1 64  ? 24.79300 35.06500 21.63000  1.000 79.65000  ? 62  LYS A HD3  1 
ATOM   959  H HE2  . LYS A 1 64  ? 24.03400 36.94000 20.60300  1.000 70.74000  ? 62  LYS A HE2  1 
ATOM   960  H HE3  . LYS A 1 64  ? 24.19900 35.87200 19.43700  1.000 70.74000  ? 62  LYS A HE3  1 
ATOM   961  H HZ1  . LYS A 1 64  ? 22.19500 36.93600 19.26300  1.000 82.90000  ? 62  LYS A HZ1  1 
ATOM   962  H HZ2  . LYS A 1 64  ? 21.94800 35.53300 19.52600  1.000 82.90000  ? 62  LYS A HZ2  1 
ATOM   963  H HZ3  . LYS A 1 64  ? 21.79800 36.50600 20.58900  1.000 82.90000  ? 62  LYS A HZ3  1 
ATOM   964  N N    . PRO A 1 65  ? 23.57100 29.88200 19.82900  1.000 50.69000  ? 63  PRO A N    1 
ATOM   965  C CA   . PRO A 1 65  ? 22.93600 29.38400 18.59900  1.000 42.91000  ? 63  PRO A CA   1 
ATOM   966  C C    . PRO A 1 65  ? 22.30600 30.51400 17.79800  1.000 49.27000  ? 63  PRO A C    1 
ATOM   967  O O    . PRO A 1 65  ? 21.62300 31.38600 18.34600  1.000 50.04000  ? 63  PRO A O    1 
ATOM   968  C CB   . PRO A 1 65  ? 21.88200 28.39800 19.12000  1.000 52.68000  ? 63  PRO A CB   1 
ATOM   969  C CG   . PRO A 1 65  ? 22.45700 27.89500 20.40400  1.000 58.90000  ? 63  PRO A CG   1 
ATOM   970  C CD   . PRO A 1 65  ? 23.21700 29.06200 21.00500  1.000 55.67000  ? 63  PRO A CD   1 
ATOM   971  H HA   . PRO A 1 65  ? 23.58000 28.91200 18.04800  1.000 51.34000  ? 63  PRO A HA   1 
ATOM   972  H HB2  . PRO A 1 65  ? 21.04400 28.86200 19.27400  1.000 63.07000  ? 63  PRO A HB2  1 
ATOM   973  H HB3  . PRO A 1 65  ? 21.76600 27.67400 18.48500  1.000 63.07000  ? 63  PRO A HB3  1 
ATOM   974  H HG2  . PRO A 1 65  ? 21.74000 27.61400 20.99300  1.000 70.54000  ? 63  PRO A HG2  1 
ATOM   975  H HG3  . PRO A 1 65  ? 23.05700 27.15400 20.22300  1.000 70.54000  ? 63  PRO A HG3  1 
ATOM   976  H HD2  . PRO A 1 65  ? 22.64600 29.56300 21.60800  1.000 66.66000  ? 63  PRO A HD2  1 
ATOM   977  H HD3  . PRO A 1 65  ? 24.01800 28.74700 21.45200  1.000 66.66000  ? 63  PRO A HD3  1 
ATOM   978  N N    . ILE A 1 66  ? 22.55400 30.50100 16.48800  1.000 41.56000  ? 64  ILE A N    1 
ATOM   979  C CA   . ILE A 1 66  ? 22.00000 31.48300 15.57500  1.000 39.55000  ? 64  ILE A CA   1 
ATOM   980  C C    . ILE A 1 66  ? 20.93900 30.86900 14.67200  1.000 41.90000  ? 64  ILE A C    1 
ATOM   981  O O    . ILE A 1 66  ? 19.92500 31.50500 14.38200  1.000 47.40000  ? 64  ILE A O    1 
ATOM   982  C CB   . ILE A 1 66  ? 23.11400 32.14100 14.73000  1.000 39.56000  ? 64  ILE A CB   1 
ATOM   983  C CG1  . ILE A 1 66  ? 24.19500 32.74800 15.62900  1.000 44.21000  ? 64  ILE A CG1  1 
ATOM   984  C CG2  . ILE A 1 66  ? 22.51900 33.19700 13.79500  1.000 48.23000  ? 64  ILE A CG2  1 
ATOM   985  C CD1  . ILE A 1 66  ? 23.71500 33.88100 16.50700  1.000 50.63000  ? 64  ILE A CD1  1 
ATOM   986  H H    . ILE A 1 66  ? 23.05200 29.91600 16.10200  1.000 49.73000  ? 64  ILE A H    1 
ATOM   987  H HA   . ILE A 1 66  ? 21.57000 32.18300 16.09000  1.000 47.32000  ? 64  ILE A HA   1 
ATOM   988  H HB   . ILE A 1 66  ? 23.52600 31.45200 14.18500  1.000 47.33000  ? 64  ILE A HB   1 
ATOM   989  H HG12 . ILE A 1 66  ? 24.54900 32.05500 16.20800  1.000 52.90000  ? 64  ILE A HG12 1 
ATOM   990  H HG13 . ILE A 1 66  ? 24.90500 33.09500 15.06600  1.000 52.90000  ? 64  ILE A HG13 1 
ATOM   991  H HG21 . ILE A 1 66  ? 23.23800 33.74400 13.44200  1.000 57.73000  ? 64  ILE A HG21 1 
ATOM   992  H HG22 . ILE A 1 66  ? 22.05500 32.75300 13.06800  1.000 57.73000  ? 64  ILE A HG22 1 
ATOM   993  H HG23 . ILE A 1 66  ? 21.90000 33.75000 14.29700  1.000 57.73000  ? 64  ILE A HG23 1 
ATOM   994  H HD11 . ILE A 1 66  ? 24.46600 34.21700 17.02100  1.000 60.61000  ? 64  ILE A HD11 1 
ATOM   995  H HD12 . ILE A 1 66  ? 23.35600 34.58700 15.94800  1.000 60.61000  ? 64  ILE A HD12 1 
ATOM   996  H HD13 . ILE A 1 66  ? 23.02900 33.54900 17.10700  1.000 60.61000  ? 64  ILE A HD13 1 
ATOM   997  N N    . ARG A 1 67  ? 21.16200 29.64400 14.21000  1.000 40.61000  ? 65  ARG A N    1 
ATOM   998  C CA   . ARG A 1 67  ? 20.20000 28.91300 13.39100  1.000 42.83000  ? 65  ARG A CA   1 
ATOM   999  C C    . ARG A 1 67  ? 19.73500 27.70700 14.20500  1.000 50.58000  ? 65  ARG A C    1 
ATOM   1000 O O    . ARG A 1 67  ? 20.16600 26.57300 13.98100  1.000 45.25000  ? 65  ARG A O    1 
ATOM   1001 C CB   . ARG A 1 67  ? 20.81700 28.50000 12.05500  1.000 34.71000  ? 65  ARG A CB   1 
ATOM   1002 C CG   . ARG A 1 67  ? 21.07800 29.66600 11.11000  1.000 37.76000  ? 65  ARG A CG   1 
ATOM   1003 C CD   . ARG A 1 67  ? 19.79300 30.19800 10.50400  1.000 38.88000  ? 65  ARG A CD   1 
ATOM   1004 N NE   . ARG A 1 67  ? 18.98900 29.13000 9.92300   1.000 39.89000  ? 65  ARG A NE   1 
ATOM   1005 C CZ   . ARG A 1 67  ? 19.11300 28.68600 8.67800   1.000 45.82000  ? 65  ARG A CZ   1 
ATOM   1006 N NH1  . ARG A 1 67  ? 19.97100 29.23700 7.82800   1.000 40.12000  ? 65  ARG A NH1  1 
ATOM   1007 N NH2  . ARG A 1 67  ? 18.36300 27.66300 8.27400   1.000 36.85000  ? 65  ARG A NH2  1 
ATOM   1008 H H    . ARG A 1 67  ? 21.88300 29.20300 14.36100  1.000 48.58000  ? 65  ARG A H    1 
ATOM   1009 H HA   . ARG A 1 67  ? 19.43000 29.47500 13.21200  1.000 51.25000  ? 65  ARG A HA   1 
ATOM   1010 H HB2  . ARG A 1 67  ? 21.67000 28.07200 12.23000  1.000 41.50000  ? 65  ARG A HB2  1 
ATOM   1011 H HB3  . ARG A 1 67  ? 20.22400 27.87200 11.61600  1.000 41.50000  ? 65  ARG A HB3  1 
ATOM   1012 H HG2  . ARG A 1 67  ? 21.50400 30.38600 11.60000  1.000 45.17000  ? 65  ARG A HG2  1 
ATOM   1013 H HG3  . ARG A 1 67  ? 21.65100 29.36700 10.38800  1.000 45.17000  ? 65  ARG A HG3  1 
ATOM   1014 H HD2  . ARG A 1 67  ? 19.26800 30.62200 11.20100  1.000 46.51000  ? 65  ARG A HD2  1 
ATOM   1015 H HD3  . ARG A 1 67  ? 20.00400 30.84200 9.81300   1.000 46.51000  ? 65  ARG A HD3  1 
ATOM   1016 H HE   . ARG A 1 67  ? 18.39200 28.76200 10.42000  1.000 47.72000  ? 65  ARG A HE   1 
ATOM   1017 H HH11 . ARG A 1 67  ? 20.46400 29.89600 8.07400   1.000 47.99000  ? 65  ARG A HH11 1 
ATOM   1018 H HH12 . ARG A 1 67  ? 20.03400 28.93200 7.02600   1.000 47.99000  ? 65  ARG A HH12 1 
ATOM   1019 H HH21 . ARG A 1 67  ? 17.80300 27.30000 8.81700   1.000 44.07000  ? 65  ARG A HH21 1 
ATOM   1020 H HH22 . ARG A 1 67  ? 18.43400 27.36900 7.46900   1.000 44.07000  ? 65  ARG A HH22 1 
ATOM   1021 N N    . THR A 1 68  ? 18.84200 27.96000 15.16500  1.000 43.48000  ? 66  THR A N    1 
ATOM   1022 C CA   . THR A 1 68  ? 18.35000 26.88000 16.01300  1.000 46.00000  ? 66  THR A CA   1 
ATOM   1023 C C    . THR A 1 68  ? 17.54100 25.84400 15.24400  1.000 48.11000  ? 66  THR A C    1 
ATOM   1024 O O    . THR A 1 68  ? 17.28900 24.75700 15.77800  1.000 46.48000  ? 66  THR A O    1 
ATOM   1025 C CB   . THR A 1 68  ? 17.49600 27.46100 17.14000  1.000 54.80000  ? 66  THR A CB   1 
ATOM   1026 O OG1  . THR A 1 68  ? 16.48400 28.31700 16.58100  1.000 51.20000  ? 66  THR A OG1  1 
ATOM   1027 C CG2  . THR A 1 68  ? 18.36200 28.27000 18.08900  1.000 48.20000  ? 66  THR A CG2  1 
ATOM   1028 H H    . THR A 1 68  ? 18.51400 28.73500 15.34100  1.000 52.03000  ? 66  THR A H    1 
ATOM   1029 H HA   . THR A 1 68  ? 19.10800 26.42600 16.41500  1.000 55.05000  ? 66  THR A HA   1 
ATOM   1030 H HB   . THR A 1 68  ? 17.07700 26.74100 17.63700  1.000 65.61000  ? 66  THR A HB   1 
ATOM   1031 H HG1  . THR A 1 68  ? 16.83900 28.99500 16.23500  1.000 61.29000  ? 66  THR A HG1  1 
ATOM   1032 H HG21 . THR A 1 68  ? 17.82000 28.62400 18.81100  1.000 57.69000  ? 66  THR A HG21 1 
ATOM   1033 H HG22 . THR A 1 68  ? 19.05800 27.70700 18.46400  1.000 57.69000  ? 66  THR A HG22 1 
ATOM   1034 H HG23 . THR A 1 68  ? 18.77500 29.00800 17.61500  1.000 57.69000  ? 66  THR A HG23 1 
ATOM   1035 N N    . ASP A 1 69  ? 17.14300 26.14300 14.00800  1.000 46.26000  ? 67  ASP A N    1 
ATOM   1036 C CA   . ASP A 1 69  ? 16.29500 25.24800 13.23700  1.000 45.52000  ? 67  ASP A CA   1 
ATOM   1037 C C    . ASP A 1 69  ? 17.06300 24.14000 12.53100  1.000 52.16000  ? 67  ASP A C    1 
ATOM   1038 O O    . ASP A 1 69  ? 16.43200 23.20700 12.02000  1.000 54.34000  ? 67  ASP A O    1 
ATOM   1039 C CB   . ASP A 1 69  ? 15.51300 26.04900 12.19000  1.000 46.71000  ? 67  ASP A CB   1 
ATOM   1040 C CG   . ASP A 1 69  ? 16.42100 26.86100 11.27400  1.000 46.45000  ? 67  ASP A CG   1 
ATOM   1041 O OD1  . ASP A 1 69  ? 17.38800 27.48000 11.77100  1.000 48.83000  ? 67  ASP A OD1  1 
ATOM   1042 O OD2  . ASP A 1 69  ? 16.16500 26.88800 10.05300  1.000 51.34000  ? 67  ASP A OD2  1 
ATOM   1043 H H    . ASP A 1 69  ? 17.35400 26.86700 13.59500  1.000 55.37000  ? 67  ASP A H    1 
ATOM   1044 H HA   . ASP A 1 69  ? 15.65400 24.83200 13.83300  1.000 54.48000  ? 67  ASP A HA   1 
ATOM   1045 H HB2  . ASP A 1 69  ? 15.00200 25.43500 11.63800  1.000 55.90000  ? 67  ASP A HB2  1 
ATOM   1046 H HB3  . ASP A 1 69  ? 14.91600 26.66400 12.64300  1.000 55.90000  ? 67  ASP A HB3  1 
ATOM   1047 N N    . VAL A 1 70  ? 18.39200 24.21200 12.48300  1.000 42.90000  ? 68  VAL A N    1 
ATOM   1048 C CA   . VAL A 1 70  ? 19.18700 23.24300 11.74100  1.000 44.11000  ? 68  VAL A CA   1 
ATOM   1049 C C    . VAL A 1 70  ? 19.87600 22.29800 12.71400  1.000 45.85000  ? 68  VAL A C    1 
ATOM   1050 O O    . VAL A 1 70  ? 20.14700 22.64300 13.86900  1.000 50.06000  ? 68  VAL A O    1 
ATOM   1051 C CB   . VAL A 1 70  ? 20.23600 23.92000 10.82700  1.000 51.40000  ? 68  VAL A CB   1 
ATOM   1052 C CG1  . VAL A 1 70  ? 19.55900 24.88100 9.86900   1.000 49.66000  ? 68  VAL A CG1  1 
ATOM   1053 C CG2  . VAL A 1 70  ? 21.29500 24.63500 11.66700  1.000 46.74000  ? 68  VAL A CG2  1 
ATOM   1054 H H    . VAL A 1 70  ? 18.85800 24.81700 12.87600  1.000 51.33000  ? 68  VAL A H    1 
ATOM   1055 H HA   . VAL A 1 70  ? 18.60200 22.71400 11.17700  1.000 52.79000  ? 68  VAL A HA   1 
ATOM   1056 H HB   . VAL A 1 70  ? 20.68200 23.23800 10.30100  1.000 61.54000  ? 68  VAL A HB   1 
ATOM   1057 H HG11 . VAL A 1 70  ? 20.23000 25.26300 9.28000   1.000 59.44000  ? 68  VAL A HG11 1 
ATOM   1058 H HG12 . VAL A 1 70  ? 18.90000 24.39600 9.34800   1.000 59.44000  ? 68  VAL A HG12 1 
ATOM   1059 H HG13 . VAL A 1 70  ? 19.12700 25.58400 10.37800  1.000 59.44000  ? 68  VAL A HG13 1 
ATOM   1060 H HG21 . VAL A 1 70  ? 21.71500 25.32300 11.12700  1.000 55.94000  ? 68  VAL A HG21 1 
ATOM   1061 H HG22 . VAL A 1 70  ? 20.86800 25.03400 12.43800  1.000 55.94000  ? 68  VAL A HG22 1 
ATOM   1062 H HG23 . VAL A 1 70  ? 21.95800 23.98800 11.95600  1.000 55.94000  ? 68  VAL A HG23 1 
ATOM   1063 N N    . THR A 1 71  ? 20.17200 21.10100 12.22600  1.000 44.80000  ? 69  THR A N    1 
ATOM   1064 C CA   . THR A 1 71  ? 20.88200 20.08600 12.98300  1.000 44.25000  ? 69  THR A CA   1 
ATOM   1065 C C    . THR A 1 71  ? 22.36900 20.15800 12.66500  1.000 48.87000  ? 69  THR A C    1 
ATOM   1066 O O    . THR A 1 71  ? 22.77100 20.59000 11.58100  1.000 49.54000  ? 69  THR A O    1 
ATOM   1067 C CB   . THR A 1 71  ? 20.34700 18.69300 12.65600  1.000 49.44000  ? 69  THR A CB   1 
ATOM   1068 O OG1  . THR A 1 71  ? 20.76900 18.31300 11.33900  1.000 59.41000  ? 69  THR A OG1  1 
ATOM   1069 C CG2  . THR A 1 71  ? 18.82500 18.68100 12.71800  1.000 56.53000  ? 69  THR A CG2  1 
ATOM   1070 H H    . THR A 1 71  ? 19.96400 20.84800 11.43000  1.000 53.61000  ? 69  THR A H    1 
ATOM   1071 H HA   . THR A 1 71  ? 20.76100 20.24600 13.93200  1.000 52.95000  ? 69  THR A HA   1 
ATOM   1072 H HB   . THR A 1 71  ? 20.68600 18.05500 13.30300  1.000 59.18000  ? 69  THR A HB   1 
ATOM   1073 H HG1  . THR A 1 71  ? 20.47500 18.86000 10.77400  1.000 71.15000  ? 69  THR A HG1  1 
ATOM   1074 H HG21 . THR A 1 71  ? 18.49900 17.77000 12.66400  1.000 67.68000  ? 69  THR A HG21 1 
ATOM   1075 H HG22 . THR A 1 71  ? 18.52500 19.07400 13.55300  1.000 67.68000  ? 69  THR A HG22 1 
ATOM   1076 H HG23 . THR A 1 71  ? 18.45800 19.19200 11.98000  1.000 67.68000  ? 69  THR A HG23 1 
ATOM   1077 N N    . GLY A 1 72  ? 23.18300 19.73600 13.62500  1.000 44.33000  ? 70  GLY A N    1 
ATOM   1078 C CA   . GLY A 1 72  ? 24.61400 19.68500 13.39000  1.000 50.33000  ? 70  GLY A CA   1 
ATOM   1079 C C    . GLY A 1 72  ? 24.95400 18.68800 12.29700  1.000 54.30000  ? 70  GLY A C    1 
ATOM   1080 O O    . GLY A 1 72  ? 24.39100 17.59400 12.22700  1.000 51.55000  ? 70  GLY A O    1 
ATOM   1081 H H    . GLY A 1 72  ? 22.93600 19.47700 14.40700  1.000 53.05000  ? 70  GLY A H    1 
ATOM   1082 H HA2  . GLY A 1 72  ? 24.93300 20.56200 13.12100  1.000 60.25000  ? 70  GLY A HA2  1 
ATOM   1083 H HA3  . GLY A 1 72  ? 25.07100 19.42300 14.20400  1.000 60.25000  ? 70  GLY A HA3  1 
ATOM   1084 N N    . MET A 1 73  ? 25.88100 19.07700 11.43300  1.000 49.19000  ? 71  MET A N    1 
ATOM   1085 C CA   . MET A 1 73  ? 26.30000 18.25200 10.31000  1.000 46.23000  ? 71  MET A CA   1 
ATOM   1086 C C    . MET A 1 73  ? 27.76500 17.87900 10.48700  1.000 43.74000  ? 71  MET A C    1 
ATOM   1087 O O    . MET A 1 73  ? 28.54000 18.61400 11.11000  1.000 43.41000  ? 71  MET A O    1 
ATOM   1088 C CB   . MET A 1 73  ? 26.07800 18.99400 8.97600   1.000 45.06000  ? 71  MET A CB   1 
ATOM   1089 C CG   . MET A 1 73  ? 26.37400 18.16200 7.74200   1.000 52.83000  ? 71  MET A CG   1 
ATOM   1090 S SD   . MET A 1 73  ? 25.64500 18.74700 6.18100   1.000 65.44000  ? 71  MET A SD   1 
ATOM   1091 C CE   . MET A 1 73  ? 24.39300 19.91600 6.71800   1.000 47.86000  ? 71  MET A CE   1 
ATOM   1092 H H    . MET A 1 73  ? 26.29100 19.83200 11.47700  1.000 58.88000  ? 71  MET A H    1 
ATOM   1093 H HA   . MET A 1 73  ? 25.76900 17.44100 10.29100  1.000 55.33000  ? 71  MET A HA   1 
ATOM   1094 H HB2  . MET A 1 73  ? 25.14900 19.25900 8.96200   1.000 53.93000  ? 71  MET A HB2  1 
ATOM   1095 H HB3  . MET A 1 73  ? 26.64700 19.77900 8.95200   1.000 53.93000  ? 71  MET A HB3  1 
ATOM   1096 H HG2  . MET A 1 73  ? 27.33600 18.13400 7.61800   1.000 63.24000  ? 71  MET A HG2  1 
ATOM   1097 H HG3  . MET A 1 73  ? 26.04400 17.26300 7.89400   1.000 63.24000  ? 71  MET A HG3  1 
ATOM   1098 H HE1  . MET A 1 73  ? 23.94600 20.27600 5.93600   1.000 57.29000  ? 71  MET A HE1  1 
ATOM   1099 H HE2  . MET A 1 73  ? 23.75000 19.45700 7.28000   1.000 57.29000  ? 71  MET A HE2  1 
ATOM   1100 H HE3  . MET A 1 73  ? 24.81900 20.63300 7.21100   1.000 57.29000  ? 71  MET A HE3  1 
ATOM   1101 N N    . ILE A 1 74  ? 28.13100 16.71600 9.94500   1.000 44.05000  ? 72  ILE A N    1 
ATOM   1102 C CA   . ILE A 1 74  ? 29.49500 16.21800 10.06800  1.000 45.28000  ? 72  ILE A CA   1 
ATOM   1103 C C    . ILE A 1 74  ? 30.41700 17.04900 9.18500   1.000 41.17000  ? 72  ILE A C    1 
ATOM   1104 O O    . ILE A 1 74  ? 30.17900 17.19800 7.98100   1.000 49.01000  ? 72  ILE A O    1 
ATOM   1105 C CB   . ILE A 1 74  ? 29.56200 14.72700 9.68900   1.000 54.99000  ? 72  ILE A CB   1 
ATOM   1106 C CG1  . ILE A 1 74  ? 28.61300 13.89300 10.55800  1.000 55.94000  ? 72  ILE A CG1  1 
ATOM   1107 C CG2  . ILE A 1 74  ? 31.01000 14.22500 9.77100   1.000 51.96000  ? 72  ILE A CG2  1 
ATOM   1108 C CD1  . ILE A 1 74  ? 29.25800 13.20900 11.75800  1.000 63.24000  ? 72  ILE A CD1  1 
ATOM   1109 H H    . ILE A 1 74  ? 27.60600 16.19900 9.50200   1.000 52.71000  ? 72  ILE A H    1 
ATOM   1110 H HA   . ILE A 1 74  ? 29.78900 16.31100 10.98800  1.000 54.19000  ? 72  ILE A HA   1 
ATOM   1111 H HB   . ILE A 1 74  ? 29.27100 14.64200 8.76800   1.000 65.84000  ? 72  ILE A HB   1 
ATOM   1112 H HG12 . ILE A 1 74  ? 27.90800 14.46500 10.89800  1.000 66.99000  ? 72  ILE A HG12 1 
ATOM   1113 H HG13 . ILE A 1 74  ? 28.22400 13.19800 10.00500  1.000 66.99000  ? 72  ILE A HG13 1 
ATOM   1114 H HG21 . ILE A 1 74  ? 31.01700 13.25900 9.68000   1.000 62.20000  ? 72  ILE A HG21 1 
ATOM   1115 H HG22 . ILE A 1 74  ? 31.51900 14.62500 9.05100   1.000 62.20000  ? 72  ILE A HG22 1 
ATOM   1116 H HG23 . ILE A 1 74  ? 31.38800 14.48000 10.62700  1.000 62.20000  ? 72  ILE A HG23 1 
ATOM   1117 H HD11 . ILE A 1 74  ? 28.55900 12.87900 12.34400  1.000 75.74000  ? 72  ILE A HD11 1 
ATOM   1118 H HD12 . ILE A 1 74  ? 29.80400 12.46900 11.44900  1.000 75.74000  ? 72  ILE A HD12 1 
ATOM   1119 H HD13 . ILE A 1 74  ? 29.80700 13.85300 12.23300  1.000 75.74000  ? 72  ILE A HD13 1 
ATOM   1120 N N    . LEU A 1 75  ? 31.48000 17.58400 9.77400   1.000 43.57000  ? 73  LEU A N    1 
ATOM   1121 C CA   . LEU A 1 75  ? 32.49800 18.34600 9.05600   1.000 41.25000  ? 73  LEU A CA   1 
ATOM   1122 C C    . LEU A 1 75  ? 33.80900 17.56900 9.09800   1.000 44.89000  ? 73  LEU A C    1 
ATOM   1123 O O    . LEU A 1 75  ? 34.35200 17.31900 10.17900  1.000 43.97000  ? 73  LEU A O    1 
ATOM   1124 C CB   . LEU A 1 75  ? 32.66800 19.73800 9.66800   1.000 43.05000  ? 73  LEU A CB   1 
ATOM   1125 C CG   . LEU A 1 75  ? 33.74800 20.64300 9.08500   1.000 41.21000  ? 73  LEU A CG   1 
ATOM   1126 C CD1  . LEU A 1 75  ? 33.46400 20.98000 7.63800   1.000 42.88000  ? 73  LEU A CD1  1 
ATOM   1127 C CD2  . LEU A 1 75  ? 33.86000 21.91600 9.90400   1.000 36.25000  ? 73  LEU A CD2  1 
ATOM   1128 H H    . LEU A 1 75  ? 31.64000 17.51600 10.61600  1.000 52.14000  ? 73  LEU A H    1 
ATOM   1129 H HA   . LEU A 1 75  ? 32.23300 18.44800 8.12900   1.000 49.35000  ? 73  LEU A HA   1 
ATOM   1130 H HB2  . LEU A 1 75  ? 31.82500 20.20900 9.57600   1.000 51.52000  ? 73  LEU A HB2  1 
ATOM   1131 H HB3  . LEU A 1 75  ? 32.86900 19.62700 10.61000  1.000 51.52000  ? 73  LEU A HB3  1 
ATOM   1132 H HG   . LEU A 1 75  ? 34.60100 20.18400 9.12500   1.000 49.30000  ? 73  LEU A HG   1 
ATOM   1133 H HD11 . LEU A 1 75  ? 34.16900 21.55700 7.30600   1.000 51.31000  ? 73  LEU A HD11 1 
ATOM   1134 H HD12 . LEU A 1 75  ? 33.43700 20.15900 7.12200   1.000 51.31000  ? 73  LEU A HD12 1 
ATOM   1135 H HD13 . LEU A 1 75  ? 32.61000 21.43600 7.58300   1.000 51.31000  ? 73  LEU A HD13 1 
ATOM   1136 H HD21 . LEU A 1 75  ? 34.55000 22.47900 9.51900   1.000 43.36000  ? 73  LEU A HD21 1 
ATOM   1137 H HD22 . LEU A 1 75  ? 33.00700 22.37800 9.88500   1.000 43.36000  ? 73  LEU A HD22 1 
ATOM   1138 H HD23 . LEU A 1 75  ? 34.09300 21.68500 10.81700  1.000 43.36000  ? 73  LEU A HD23 1 
ATOM   1139 N N    . GLU A 1 76  ? 34.31400 17.19100 7.92600   1.000 46.57000  ? 74  GLU A N    1 
ATOM   1140 C CA   . GLU A 1 76  ? 35.55600 16.43700 7.80600   1.000 46.27000  ? 74  GLU A CA   1 
ATOM   1141 C C    . GLU A 1 76  ? 36.48900 17.15000 6.83600   1.000 42.20000  ? 74  GLU A C    1 
ATOM   1142 O O    . GLU A 1 76  ? 36.09400 18.06500 6.10800   1.000 42.18000  ? 74  GLU A O    1 
ATOM   1143 C CB   . GLU A 1 76  ? 35.28200 14.99700 7.35100   1.000 46.41000  ? 74  GLU A CB   1 
ATOM   1144 C CG   . GLU A 1 76  ? 34.26000 14.27500 8.23600   1.000 50.65000  ? 74  GLU A CG   1 
ATOM   1145 C CD   . GLU A 1 76  ? 34.26100 12.76800 8.05400   1.000 55.85000  ? 74  GLU A CD   1 
ATOM   1146 O OE1  . GLU A 1 76  ? 34.64000 12.29000 6.96400   1.000 53.07000  ? 74  GLU A OE1  1 
ATOM   1147 O OE2  . GLU A 1 76  ? 33.86500 12.05900 9.00400   1.000 57.59000  ? 74  GLU A OE2  1 
ATOM   1148 H H    . GLU A 1 76  ? 33.94500 17.36500 7.16900   1.000 55.73000  ? 74  GLU A H    1 
ATOM   1149 H HA   . GLU A 1 76  ? 35.99400 16.40000 8.67200   1.000 55.37000  ? 74  GLU A HA   1 
ATOM   1150 H HB2  . GLU A 1 76  ? 34.93400 15.01300 6.44600   1.000 55.55000  ? 74  GLU A HB2  1 
ATOM   1151 H HB3  . GLU A 1 76  ? 36.11100 14.49400 7.37900   1.000 55.55000  ? 74  GLU A HB3  1 
ATOM   1152 H HG2  . GLU A 1 76  ? 34.45600 14.46500 9.16700   1.000 60.64000  ? 74  GLU A HG2  1 
ATOM   1153 H HG3  . GLU A 1 76  ? 33.37700 14.60000 8.00900   1.000 60.64000  ? 74  GLU A HG3  1 
ATOM   1154 N N    . GLU A 1 77  ? 37.74900 16.72400 6.83700   1.000 34.36000  ? 75  GLU A N    1 
ATOM   1155 C CA   . GLU A 1 77  ? 38.78200 17.33700 6.00300   1.000 38.30000  ? 75  GLU A CA   1 
ATOM   1156 C C    . GLU A 1 77  ? 38.77700 16.63300 4.65200   1.000 44.20000  ? 75  GLU A C    1 
ATOM   1157 O O    . GLU A 1 77  ? 39.47400 15.64000 4.43600   1.000 38.58000  ? 75  GLU A O    1 
ATOM   1158 C CB   . GLU A 1 77  ? 40.13900 17.24800 6.68600   1.000 38.85000  ? 75  GLU A CB   1 
ATOM   1159 C CG   . GLU A 1 77  ? 41.26700 17.89100 5.90600   1.000 48.11000  ? 75  GLU A CG   1 
ATOM   1160 C CD   . GLU A 1 77  ? 42.61300 17.73300 6.59200   1.000 65.07000  ? 75  GLU A CD   1 
ATOM   1161 O OE1  . GLU A 1 77  ? 42.66400 17.81900 7.84200   1.000 71.88000  ? 75  GLU A OE1  1 
ATOM   1162 O OE2  . GLU A 1 77  ? 43.61800 17.52300 5.87900   1.000 54.18000  ? 75  GLU A OE2  1 
ATOM   1163 H H    . GLU A 1 77  ? 38.03600 16.07200 7.31900   1.000 41.08000  ? 75  GLU A H    1 
ATOM   1164 H HA   . GLU A 1 77  ? 38.57000 18.27300 5.86200   1.000 45.81000  ? 75  GLU A HA   1 
ATOM   1165 H HB2  . GLU A 1 77  ? 40.08400 17.69200 7.54600   1.000 46.47000  ? 75  GLU A HB2  1 
ATOM   1166 H HB3  . GLU A 1 77  ? 40.36400 16.31300 6.81400   1.000 46.47000  ? 75  GLU A HB3  1 
ATOM   1167 H HG2  . GLU A 1 77  ? 41.32700 17.47700 5.03200   1.000 57.58000  ? 75  GLU A HG2  1 
ATOM   1168 H HG3  . GLU A 1 77  ? 41.08700 18.84000 5.81200   1.000 57.58000  ? 75  GLU A HG3  1 
ATOM   1169 N N    . GLY A 1 78  ? 37.98600 17.16000 3.72500   1.000 40.84000  ? 76  GLY A N    1 
ATOM   1170 C CA   . GLY A 1 78  ? 37.91000 16.56000 2.40900   1.000 41.61000  ? 76  GLY A CA   1 
ATOM   1171 C C    . GLY A 1 78  ? 37.16000 15.23900 2.43400   1.000 40.05000  ? 76  GLY A C    1 
ATOM   1172 O O    . GLY A 1 78  ? 36.57400 14.82600 3.43500   1.000 37.67000  ? 76  GLY A O    1 
ATOM   1173 H H    . GLY A 1 78  ? 37.49200 17.85500 3.83400   1.000 48.86000  ? 76  GLY A H    1 
ATOM   1174 H HA2  . GLY A 1 78  ? 37.45600 17.16400 1.80100   1.000 49.79000  ? 76  GLY A HA2  1 
ATOM   1175 H HA3  . GLY A 1 78  ? 38.80500 16.40100 2.07400   1.000 49.79000  ? 76  GLY A HA3  1 
ATOM   1176 N N    . ALA A 1 79  ? 37.18800 14.57400 1.27600   1.000 38.57000  ? 77  ALA A N    1 
ATOM   1177 C CA   . ALA A 1 79  ? 36.48600 13.31900 1.08600   1.000 41.04000  ? 77  ALA A CA   1 
ATOM   1178 C C    . ALA A 1 79  ? 37.43300 12.25900 0.55400   1.000 44.62000  ? 77  ALA A C    1 
ATOM   1179 O O    . ALA A 1 79  ? 38.44000 12.59200 -0.09000  1.000 40.08000  ? 77  ALA A O    1 
ATOM   1180 C CB   . ALA A 1 79  ? 35.31700 13.47800 0.09600   1.000 44.62000  ? 77  ALA A CB   1 
ATOM   1181 H H    . ALA A 1 79  ? 37.61600 14.83900 0.58000   1.000 46.14000  ? 77  ALA A H    1 
ATOM   1182 H HA   . ALA A 1 79  ? 36.12800 13.02300 1.93700   1.000 49.10000  ? 77  ALA A HA   1 
ATOM   1183 H HB1  . ALA A 1 79  ? 34.87000 12.62300 -0.00400  1.000 53.40000  ? 77  ALA A HB1  1 
ATOM   1184 H HB2  . ALA A 1 79  ? 34.69600 14.13700 0.44300   1.000 53.40000  ? 77  ALA A HB2  1 
ATOM   1185 H HB3  . ALA A 1 79  ? 35.66700 13.77100 -0.75900  1.000 53.40000  ? 77  ALA A HB3  1 
ATOM   1186 N N    . PRO A 1 80  ? 37.13700 10.98100 0.78500   1.000 46.21000  ? 78  PRO A N    1 
ATOM   1187 C CA   . PRO A 1 80  ? 37.94000 9.92000  0.17500   1.000 44.00000  ? 78  PRO A CA   1 
ATOM   1188 C C    . PRO A 1 80  ? 38.10500 10.15600 -1.31900  1.000 43.84000  ? 78  PRO A C    1 
ATOM   1189 O O    . PRO A 1 80  ? 37.17400 10.57100 -2.00900  1.000 39.00000  ? 78  PRO A O    1 
ATOM   1190 C CB   . PRO A 1 80  ? 37.13600 8.64800  0.46400   1.000 48.43000  ? 78  PRO A CB   1 
ATOM   1191 C CG   . PRO A 1 80  ? 36.36000 8.97000  1.69300   1.000 50.93000  ? 78  PRO A CG   1 
ATOM   1192 C CD   . PRO A 1 80  ? 36.05300 10.44800 1.63900   1.000 44.18000  ? 78  PRO A CD   1 
ATOM   1193 H HA   . PRO A 1 80  ? 38.81100 9.86200  0.59900   1.000 52.65000  ? 78  PRO A HA   1 
ATOM   1194 H HB2  . PRO A 1 80  ? 36.54300 8.45800  -0.28000  1.000 57.97000  ? 78  PRO A HB2  1 
ATOM   1195 H HB3  . PRO A 1 80  ? 37.74100 7.90600  0.62200   1.000 57.97000  ? 78  PRO A HB3  1 
ATOM   1196 H HG2  . PRO A 1 80  ? 35.53900 8.45400  1.70000   1.000 60.96000  ? 78  PRO A HG2  1 
ATOM   1197 H HG3  . PRO A 1 80  ? 36.89600 8.76400  2.47600   1.000 60.96000  ? 78  PRO A HG3  1 
ATOM   1198 H HD2  . PRO A 1 80  ? 35.18900 10.60000 1.22500   1.000 52.87000  ? 78  PRO A HD2  1 
ATOM   1199 H HD3  . PRO A 1 80  ? 36.09800 10.83400 2.52700   1.000 52.87000  ? 78  PRO A HD3  1 
ATOM   1200 N N    . GLU A 1 81  ? 39.31800 9.89900  -1.80600  1.000 46.65000  ? 79  GLU A N    1 
ATOM   1201 C CA   . GLU A 1 81  ? 39.63800 10.12200 -3.20900  1.000 41.01000  ? 79  GLU A CA   1 
ATOM   1202 C C    . GLU A 1 81  ? 38.67100 9.35400  -4.09800  1.000 50.21000  ? 79  GLU A C    1 
ATOM   1203 O O    . GLU A 1 81  ? 38.36000 8.18900  -3.84500  1.000 50.03000  ? 79  GLU A O    1 
ATOM   1204 C CB   . GLU A 1 81  ? 41.08100 9.69600  -3.49300  1.000 44.47000  ? 79  GLU A CB   1 
ATOM   1205 C CG   . GLU A 1 81  ? 42.14300 10.64000 -2.92400  1.000 41.29000  ? 79  GLU A CG   1 
ATOM   1206 C CD   . GLU A 1 81  ? 42.30300 10.52400 -1.41400  1.000 46.93000  ? 79  GLU A CD   1 
ATOM   1207 O OE1  . GLU A 1 81  ? 41.64000 9.66100  -0.80100  1.000 45.44000  ? 79  GLU A OE1  1 
ATOM   1208 O OE2  . GLU A 1 81  ? 43.09800 11.30200 -0.83800  1.000 49.03000  ? 79  GLU A OE2  1 
ATOM   1209 H H    . GLU A 1 81  ? 39.97100 9.59000  -1.34100  1.000 55.83000  ? 79  GLU A H    1 
ATOM   1210 H HA   . GLU A 1 81  ? 39.55300 11.06700 -3.41200  1.000 49.07000  ? 79  GLU A HA   1 
ATOM   1211 H HB2  . GLU A 1 81  ? 41.22800 8.81800  -3.10500  1.000 53.22000  ? 79  GLU A HB2  1 
ATOM   1212 H HB3  . GLU A 1 81  ? 41.20800 9.65400  -4.45400  1.000 53.22000  ? 79  GLU A HB3  1 
ATOM   1213 H HG2  . GLU A 1 81  ? 42.99800 10.43300 -3.33200  1.000 49.40000  ? 79  GLU A HG2  1 
ATOM   1214 H HG3  . GLU A 1 81  ? 41.89200 11.55400 -3.12800  1.000 49.40000  ? 79  GLU A HG3  1 
ATOM   1215 N N    . GLY A 1 82  ? 38.18400 10.01800 -5.14200  1.000 46.94000  ? 80  GLY A N    1 
ATOM   1216 C CA   . GLY A 1 82  ? 37.21200 9.43000  -6.03400  1.000 43.57000  ? 80  GLY A CA   1 
ATOM   1217 C C    . GLY A 1 82  ? 35.76600 9.64200  -5.64300  1.000 46.81000  ? 80  GLY A C    1 
ATOM   1218 O O    . GLY A 1 82  ? 34.87400 9.31900  -6.43900  1.000 47.22000  ? 80  GLY A O    1 
ATOM   1219 H H    . GLY A 1 82  ? 38.40800 10.82300 -5.35100  1.000 56.18000  ? 80  GLY A H    1 
ATOM   1220 H HA2  . GLY A 1 82  ? 37.33700 9.80100  -6.92200  1.000 52.14000  ? 80  GLY A HA2  1 
ATOM   1221 H HA3  . GLY A 1 82  ? 37.37000 8.47400  -6.08500  1.000 52.14000  ? 80  GLY A HA3  1 
ATOM   1222 N N    . THR A 1 83  ? 35.50100 10.17400 -4.44900  1.000 43.87000  ? 81  THR A N    1 
ATOM   1223 C CA   . THR A 1 83  ? 34.12900 10.43600 -4.03600  1.000 38.81000  ? 81  THR A CA   1 
ATOM   1224 C C    . THR A 1 83  ? 33.50000 11.48800 -4.94200  1.000 45.84000  ? 81  THR A C    1 
ATOM   1225 O O    . THR A 1 83  ? 34.09000 12.54600 -5.20000  1.000 40.90000  ? 81  THR A O    1 
ATOM   1226 C CB   . THR A 1 83  ? 34.09100 10.91400 -2.58700  1.000 40.93000  ? 81  THR A CB   1 
ATOM   1227 O OG1  . THR A 1 83  ? 34.87100 10.03900 -1.76400  1.000 39.87000  ? 81  THR A OG1  1 
ATOM   1228 C CG2  . THR A 1 83  ? 32.65800 10.94800 -2.07000  1.000 44.26000  ? 81  THR A CG2  1 
ATOM   1229 H H    . THR A 1 83  ? 36.09500 10.38900 -3.86500  1.000 52.50000  ? 81  THR A H    1 
ATOM   1230 H HA   . THR A 1 83  ? 33.60900 9.62000  -4.10400  1.000 46.42000  ? 81  THR A HA   1 
ATOM   1231 H HB   . THR A 1 83  ? 34.45500 11.81200 -2.53500  1.000 48.97000  ? 81  THR A HB   1 
ATOM   1232 H HG1  . THR A 1 83  ? 34.85100 10.30100 -0.96600  1.000 47.70000  ? 81  THR A HG1  1 
ATOM   1233 H HG21 . THR A 1 83  ? 32.65300 11.17700 -1.12800  1.000 52.96000  ? 81  THR A HG21 1 
ATOM   1234 H HG22 . THR A 1 83  ? 32.14300 11.61100 -2.55700  1.000 52.96000  ? 81  THR A HG22 1 
ATOM   1235 H HG23 . THR A 1 83  ? 32.24400 10.07800 -2.18500  1.000 52.96000  ? 81  THR A HG23 1 
ATOM   1236 N N    . VAL A 1 84  ? 32.30800 11.19000 -5.44000  1.000 45.50000  ? 82  VAL A N    1 
ATOM   1237 C CA   . VAL A 1 84  ? 31.52500 12.15900 -6.19500  1.000 44.33000  ? 82  VAL A CA   1 
ATOM   1238 C C    . VAL A 1 84  ? 30.74600 12.99000 -5.18500  1.000 49.63000  ? 82  VAL A C    1 
ATOM   1239 O O    . VAL A 1 84  ? 29.78200 12.50500 -4.57700  1.000 46.64000  ? 82  VAL A O    1 
ATOM   1240 C CB   . VAL A 1 84  ? 30.58700 11.47800 -7.20700  1.000 44.68000  ? 82  VAL A CB   1 
ATOM   1241 C CG1  . VAL A 1 84  ? 29.75100 12.52800 -7.92000  1.000 48.87000  ? 82  VAL A CG1  1 
ATOM   1242 C CG2  . VAL A 1 84  ? 31.39900 10.67200 -8.21600  1.000 42.76000  ? 82  VAL A CG2  1 
ATOM   1243 H H    . VAL A 1 84  ? 31.92600 10.42500 -5.35400  1.000 54.46000  ? 82  VAL A H    1 
ATOM   1244 H HA   . VAL A 1 84  ? 32.12200 12.74900 -6.68200  1.000 53.05000  ? 82  VAL A HA   1 
ATOM   1245 H HB   . VAL A 1 84  ? 29.99000 10.87400 -6.73900  1.000 53.47000  ? 82  VAL A HB   1 
ATOM   1246 H HG11 . VAL A 1 84  ? 29.32400 12.11900 -8.68900  1.000 58.49000  ? 82  VAL A HG11 1 
ATOM   1247 H HG12 . VAL A 1 84  ? 29.07700 12.86500 -7.31000  1.000 58.49000  ? 82  VAL A HG12 1 
ATOM   1248 H HG13 . VAL A 1 84  ? 30.33000 13.25000 -8.20900  1.000 58.49000  ? 82  VAL A HG13 1 
ATOM   1249 H HG21 . VAL A 1 84  ? 30.79400 10.27500 -8.86100  1.000 51.16000  ? 82  VAL A HG21 1 
ATOM   1250 H HG22 . VAL A 1 84  ? 32.02000 11.26500 -8.66600  1.000 51.16000  ? 82  VAL A HG22 1 
ATOM   1251 H HG23 . VAL A 1 84  ? 31.88500 9.97700  -7.74700  1.000 51.16000  ? 82  VAL A HG23 1 
ATOM   1252 N N    . ALA A 1 85  ? 31.19300 14.21600 -4.96400  1.000 46.55000  ? 83  ALA A N    1 
ATOM   1253 C CA   . ALA A 1 85  ? 30.53200 15.12000 -4.04200  1.000 40.20000  ? 83  ALA A CA   1 
ATOM   1254 C C    . ALA A 1 85  ? 29.65400 16.08400 -4.83200  1.000 42.91000  ? 83  ALA A C    1 
ATOM   1255 O O    . ALA A 1 85  ? 29.57800 16.03400 -6.06200  1.000 38.14000  ? 83  ALA A O    1 
ATOM   1256 C CB   . ALA A 1 85  ? 31.56300 15.86100 -3.18900  1.000 38.99000  ? 83  ALA A CB   1 
ATOM   1257 H H    . ALA A 1 85  ? 31.88800 14.55200 -5.34200  1.000 55.71000  ? 83  ALA A H    1 
ATOM   1258 H HA   . ALA A 1 85  ? 29.96100 14.61100 -3.44600  1.000 48.09000  ? 83  ALA A HA   1 
ATOM   1259 H HB1  . ALA A 1 85  ? 31.09900 16.45500 -2.57800  1.000 46.64000  ? 83  ALA A HB1  1 
ATOM   1260 H HB2  . ALA A 1 85  ? 32.08200 15.21300 -2.68900  1.000 46.64000  ? 83  ALA A HB2  1 
ATOM   1261 H HB3  . ALA A 1 85  ? 32.14400 16.37300 -3.77200  1.000 46.64000  ? 83  ALA A HB3  1 
ATOM   1262 N N    . THR A 1 86  ? 28.97100 16.96300 -4.10700  1.000 40.74000  ? 84  THR A N    1 
ATOM   1263 C CA   . THR A 1 86  ? 28.13400 17.99200 -4.70300  1.000 33.26000  ? 84  THR A CA   1 
ATOM   1264 C C    . THR A 1 86  ? 28.59300 19.35300 -4.21000  1.000 37.01000  ? 84  THR A C    1 
ATOM   1265 O O    . THR A 1 86  ? 28.69800 19.57900 -3.00300  1.000 35.33000  ? 84  THR A O    1 
ATOM   1266 C CB   . THR A 1 86  ? 26.66000 17.78100 -4.35400  1.000 42.28000  ? 84  THR A CB   1 
ATOM   1267 O OG1  . THR A 1 86  ? 26.29100 16.42600 -4.64300  1.000 41.49000  ? 84  THR A OG1  1 
ATOM   1268 C CG2  . THR A 1 86  ? 25.79400 18.72900 -5.16100  1.000 39.37000  ? 84  THR A CG2  1 
ATOM   1269 H H    . THR A 1 86  ? 28.97900 16.98300 -3.24700  1.000 48.75000  ? 84  THR A H    1 
ATOM   1270 H HA   . THR A 1 86  ? 28.22600 17.96900 -5.66800  1.000 39.77000  ? 84  THR A HA   1 
ATOM   1271 H HB   . THR A 1 86  ? 26.52100 17.96200 -3.41100  1.000 50.59000  ? 84  THR A HB   1 
ATOM   1272 H HG1  . THR A 1 86  ? 25.48200 16.30200 -4.45400  1.000 49.65000  ? 84  THR A HG1  1 
ATOM   1273 H HG21 . THR A 1 86  ? 24.85800 18.57200 -4.96200  1.000 47.09000  ? 84  THR A HG21 1 
ATOM   1274 H HG22 . THR A 1 86  ? 26.01200 19.64800 -4.94300  1.000 47.09000  ? 84  THR A HG22 1 
ATOM   1275 H HG23 . THR A 1 86  ? 25.94200 18.58700 -6.10900  1.000 47.09000  ? 84  THR A HG23 1 
ATOM   1276 N N    . LEU A 1 87  ? 28.88500 20.24200 -5.14800  1.000 36.25000  ? 85  LEU A N    1 
ATOM   1277 C CA   . LEU A 1 87  ? 29.15400 21.64700 -4.85500  1.000 36.95000  ? 85  LEU A CA   1 
ATOM   1278 C C    . LEU A 1 87  ? 27.81200 22.36700 -4.92200  1.000 36.47000  ? 85  LEU A C    1 
ATOM   1279 O O    . LEU A 1 87  ? 27.18500 22.43000 -5.98600  1.000 35.81000  ? 85  LEU A O    1 
ATOM   1280 C CB   . LEU A 1 87  ? 30.16800 22.19800 -5.84800  1.000 36.85000  ? 85  LEU A CB   1 
ATOM   1281 C CG   . LEU A 1 87  ? 30.46500 23.69100 -5.80500  1.000 36.13000  ? 85  LEU A CG   1 
ATOM   1282 C CD1  . LEU A 1 87  ? 30.82400 24.14100 -4.40300  1.000 35.93000  ? 85  LEU A CD1  1 
ATOM   1283 C CD2  . LEU A 1 87  ? 31.58900 23.98800 -6.79900  1.000 37.29000  ? 85  LEU A CD2  1 
ATOM   1284 H H    . LEU A 1 87  ? 28.93500 20.05200 -5.98500  1.000 43.36000  ? 85  LEU A H    1 
ATOM   1285 H HA   . LEU A 1 87  ? 29.51300 21.73400 -3.95800  1.000 44.19000  ? 85  LEU A HA   1 
ATOM   1286 H HB2  . LEU A 1 87  ? 31.00800 21.73800 -5.70100  1.000 44.07000  ? 85  LEU A HB2  1 
ATOM   1287 H HB3  . LEU A 1 87  ? 29.84900 21.99800 -6.74200  1.000 44.07000  ? 85  LEU A HB3  1 
ATOM   1288 H HG   . LEU A 1 87  ? 29.67600 24.17900 -6.08500  1.000 43.21000  ? 85  LEU A HG   1 
ATOM   1289 H HD11 . LEU A 1 87  ? 31.13200 25.05900 -4.43700  1.000 42.97000  ? 85  LEU A HD11 1 
ATOM   1290 H HD12 . LEU A 1 87  ? 30.03700 24.07800 -3.84000  1.000 42.97000  ? 85  LEU A HD12 1 
ATOM   1291 H HD13 . LEU A 1 87  ? 31.52400 23.56700 -4.05800  1.000 42.97000  ? 85  LEU A HD13 1 
ATOM   1292 H HD21 . LEU A 1 87  ? 31.79200 24.93600 -6.77200  1.000 44.60000  ? 85  LEU A HD21 1 
ATOM   1293 H HD22 . LEU A 1 87  ? 32.37300 23.47400 -6.55200  1.000 44.60000  ? 85  LEU A HD22 1 
ATOM   1294 H HD23 . LEU A 1 87  ? 31.29600 23.73700 -7.69000  1.000 44.60000  ? 85  LEU A HD23 1 
ATOM   1295 N N    . LEU A 1 88  ? 27.34900 22.86800 -3.78000  1.000 36.37000  ? 86  LEU A N    1 
ATOM   1296 C CA   . LEU A 1 88  ? 26.01900 23.46700 -3.68700  1.000 37.58000  ? 86  LEU A CA   1 
ATOM   1297 C C    . LEU A 1 88  ? 26.13200 24.95700 -3.97400  1.000 35.27000  ? 86  LEU A C    1 
ATOM   1298 O O    . LEU A 1 88  ? 26.31300 25.78000 -3.07500  1.000 40.17000  ? 86  LEU A O    1 
ATOM   1299 C CB   . LEU A 1 88  ? 25.41000 23.19500 -2.31900  1.000 37.06000  ? 86  LEU A CB   1 
ATOM   1300 C CG   . LEU A 1 88  ? 25.33100 21.72300 -1.92400  1.000 40.19000  ? 86  LEU A CG   1 
ATOM   1301 C CD1  . LEU A 1 88  ? 24.92900 21.58000 -0.47400  1.000 48.94000  ? 86  LEU A CD1  1 
ATOM   1302 C CD2  . LEU A 1 88  ? 24.35200 21.00100 -2.83000  1.000 46.04000  ? 86  LEU A CD2  1 
ATOM   1303 H H    . LEU A 1 88  ? 27.78800 22.87300 -3.04000  1.000 43.49000  ? 86  LEU A H    1 
ATOM   1304 H HA   . LEU A 1 88  ? 25.44200 23.07300 -4.35900  1.000 44.95000  ? 86  LEU A HA   1 
ATOM   1305 H HB2  . LEU A 1 88  ? 25.94500 23.64900 -1.64900  1.000 44.32000  ? 86  LEU A HB2  1 
ATOM   1306 H HB3  . LEU A 1 88  ? 24.50700 23.55000 -2.30800  1.000 44.32000  ? 86  LEU A HB3  1 
ATOM   1307 H HG   . LEU A 1 88  ? 26.20400 21.31500 -2.03600  1.000 48.08000  ? 86  LEU A HG   1 
ATOM   1308 H HD11 . LEU A 1 88  ? 24.86800 20.63700 -0.25500  1.000 58.58000  ? 86  LEU A HD11 1 
ATOM   1309 H HD12 . LEU A 1 88  ? 25.59800 22.00700 0.08400   1.000 58.58000  ? 86  LEU A HD12 1 
ATOM   1310 H HD13 . LEU A 1 88  ? 24.06800 22.00600 -0.34200  1.000 58.58000  ? 86  LEU A HD13 1 
ATOM   1311 H HD21 . LEU A 1 88  ? 24.27900 20.07800 -2.54100  1.000 55.10000  ? 86  LEU A HD21 1 
ATOM   1312 H HD22 . LEU A 1 88  ? 23.48700 21.43600 -2.77000  1.000 55.10000  ? 86  LEU A HD22 1 
ATOM   1313 H HD23 . LEU A 1 88  ? 24.67800 21.03700 -3.74300  1.000 55.10000  ? 86  LEU A HD23 1 
ATOM   1314 N N    . ILE A 1 89  ? 26.00500 25.30600 -5.24700  1.000 35.43000  ? 87  ILE A N    1 
ATOM   1315 C CA   . ILE A 1 89  ? 26.10900 26.68700 -5.69800  1.000 37.45000  ? 87  ILE A CA   1 
ATOM   1316 C C    . ILE A 1 89  ? 24.75000 27.36000 -5.56500  1.000 43.01000  ? 87  ILE A C    1 
ATOM   1317 O O    . ILE A 1 89  ? 23.74600 26.86900 -6.09400  1.000 41.23000  ? 87  ILE A O    1 
ATOM   1318 C CB   . ILE A 1 89  ? 26.60200 26.75900 -7.15400  1.000 38.13000  ? 87  ILE A CB   1 
ATOM   1319 C CG1  . ILE A 1 89  ? 27.99100 26.13400 -7.29500  1.000 42.93000  ? 87  ILE A CG1  1 
ATOM   1320 C CG2  . ILE A 1 89  ? 26.58700 28.20200 -7.65100  1.000 39.13000  ? 87  ILE A CG2  1 
ATOM   1321 C CD1  . ILE A 1 89  ? 29.05800 26.82800 -6.51400  1.000 38.35000  ? 87  ILE A CD1  1 
ATOM   1322 H H    . ILE A 1 89  ? 25.85400 24.74800 -5.88300  1.000 42.37000  ? 87  ILE A H    1 
ATOM   1323 H HA   . ILE A 1 89  ? 26.73900 27.16400 -5.13500  1.000 44.79000  ? 87  ILE A HA   1 
ATOM   1324 H HB   . ILE A 1 89  ? 25.98800 26.24800 -7.70300  1.000 45.61000  ? 87  ILE A HB   1 
ATOM   1325 H HG12 . ILE A 1 89  ? 27.94800 25.21500 -6.99000  1.000 51.37000  ? 87  ILE A HG12 1 
ATOM   1326 H HG13 . ILE A 1 89  ? 28.24800 26.15600 -8.23000  1.000 51.37000  ? 87  ILE A HG13 1 
ATOM   1327 H HG21 . ILE A 1 89  ? 27.14400 28.26700 -8.44300  1.000 46.80000  ? 87  ILE A HG21 1 
ATOM   1328 H HG22 . ILE A 1 89  ? 25.67600 28.45500 -7.86700  1.000 46.80000  ? 87  ILE A HG22 1 
ATOM   1329 H HG23 . ILE A 1 89  ? 26.93600 28.78000 -6.95400  1.000 46.80000  ? 87  ILE A HG23 1 
ATOM   1330 H HD11 . ILE A 1 89  ? 29.92200 26.47600 -6.78000  1.000 45.88000  ? 87  ILE A HD11 1 
ATOM   1331 H HD12 . ILE A 1 89  ? 29.01800 27.77700 -6.70000  1.000 45.88000  ? 87  ILE A HD12 1 
ATOM   1332 H HD13 . ILE A 1 89  ? 28.91300 26.67000 -5.56900  1.000 45.88000  ? 87  ILE A HD13 1 
ATOM   1333 N N    . LYS A 1 90  ? 24.71800 28.48700 -4.86300  1.000 40.77000  ? 88  LYS A N    1 
ATOM   1334 C CA   . LYS A 1 90  ? 23.58100 29.39500 -4.88400  1.000 43.52000  ? 88  LYS A CA   1 
ATOM   1335 C C    . LYS A 1 90  ? 23.98700 30.62700 -5.67900  1.000 41.88000  ? 88  LYS A C    1 
ATOM   1336 O O    . LYS A 1 90  ? 25.07200 31.17700 -5.46500  1.000 36.38000  ? 88  LYS A O    1 
ATOM   1337 C CB   . LYS A 1 90  ? 23.15200 29.77700 -3.47100  1.000 44.32000  ? 88  LYS A CB   1 
ATOM   1338 C CG   . LYS A 1 90  ? 21.66400 30.05000 -3.35300  1.000 46.33000  ? 88  LYS A CG   1 
ATOM   1339 C CD   . LYS A 1 90  ? 21.29000 30.48700 -1.94300  1.000 36.34000  ? 88  LYS A CD   1 
ATOM   1340 C CE   . LYS A 1 90  ? 20.73200 29.32800 -1.13200  1.000 40.55000  ? 88  LYS A CE   1 
ATOM   1341 N NZ   . LYS A 1 90  ? 19.91300 29.81100 0.02000   1.000 35.61000  ? 88  LYS A NZ   1 
ATOM   1342 H H    . LYS A 1 90  ? 25.36000 28.75300 -4.35600  1.000 48.77000  ? 88  LYS A H    1 
ATOM   1343 H HA   . LYS A 1 90  ? 22.83100 28.97300 -5.33000  1.000 52.07000  ? 88  LYS A HA   1 
ATOM   1344 H HB2  . LYS A 1 90  ? 23.37000 29.04900 -2.86800  1.000 53.04000  ? 88  LYS A HB2  1 
ATOM   1345 H HB3  . LYS A 1 90  ? 23.62600 30.58100 -3.20400  1.000 53.04000  ? 88  LYS A HB3  1 
ATOM   1346 H HG2  . LYS A 1 90  ? 21.42100 30.76300 -3.96500  1.000 55.44000  ? 88  LYS A HG2  1 
ATOM   1347 H HG3  . LYS A 1 90  ? 21.17300 29.24200 -3.56900  1.000 55.44000  ? 88  LYS A HG3  1 
ATOM   1348 H HD2  . LYS A 1 90  ? 22.08000 30.82100 -1.49100  1.000 43.46000  ? 88  LYS A HD2  1 
ATOM   1349 H HD3  . LYS A 1 90  ? 20.61200 31.17900 -1.99100  1.000 43.46000  ? 88  LYS A HD3  1 
ATOM   1350 H HE2  . LYS A 1 90  ? 20.16200 28.78200 -1.69500  1.000 48.51000  ? 88  LYS A HE2  1 
ATOM   1351 H HE3  . LYS A 1 90  ? 21.46500 28.79800 -0.78400  1.000 48.51000  ? 88  LYS A HE3  1 
ATOM   1352 H HZ1  . LYS A 1 90  ? 19.59600 29.11800 0.48100   1.000 42.58000  ? 88  LYS A HZ1  1 
ATOM   1353 H HZ2  . LYS A 1 90  ? 20.41200 30.31300 0.56000   1.000 42.58000  ? 88  LYS A HZ2  1 
ATOM   1354 H HZ3  . LYS A 1 90  ? 19.22900 30.29900 -0.27600  1.000 42.58000  ? 88  LYS A HZ3  1 
ATOM   1355 N N    . ARG A 1 91  ? 23.13900 31.03000 -6.60500  1.000 39.54000  ? 89  ARG A N    1 
ATOM   1356 C CA   . ARG A 1 91  ? 23.43100 32.21200 -7.40800  1.000 45.73000  ? 89  ARG A CA   1 
ATOM   1357 C C    . ARG A 1 91  ? 22.64200 33.40400 -6.88700  1.000 39.80000  ? 89  ARG A C    1 
ATOM   1358 O O    . ARG A 1 91  ? 21.59700 33.23500 -6.25300  1.000 41.34000  ? 89  ARG A O    1 
ATOM   1359 C CB   . ARG A 1 91  ? 23.08100 31.96400 -8.87700  1.000 41.12000  ? 89  ARG A CB   1 
ATOM   1360 C CG   . ARG A 1 91  ? 24.10500 31.10300 -9.61400  1.000 49.07000  ? 89  ARG A CG   1 
ATOM   1361 C CD   . ARG A 1 91  ? 25.39000 31.87900 -9.89800  1.000 50.62000  ? 89  ARG A CD   1 
ATOM   1362 N NE   . ARG A 1 91  ? 26.56400 31.00900 -9.92200  1.000 50.24000  ? 89  ARG A NE   1 
ATOM   1363 C CZ   . ARG A 1 91  ? 26.86400 30.18100 -10.91500 1.000 59.43000  ? 89  ARG A CZ   1 
ATOM   1364 N NH1  . ARG A 1 91  ? 26.10900 30.09900 -11.99900 1.000 58.18000  ? 89  ARG A NH1  1 
ATOM   1365 N NH2  . ARG A 1 91  ? 27.95200 29.41700 -10.81800 1.000 50.16000  ? 89  ARG A NH2  1 
ATOM   1366 H H    . ARG A 1 91  ? 22.39300 30.64500 -6.79200  1.000 47.31000  ? 89  ARG A H    1 
ATOM   1367 H HA   . ARG A 1 91  ? 24.37700 32.40700 -7.34500  1.000 54.73000  ? 89  ARG A HA   1 
ATOM   1368 H HB2  . ARG A 1 91  ? 22.22500 31.51100 -8.92200  1.000 49.20000  ? 89  ARG A HB2  1 
ATOM   1369 H HB3  . ARG A 1 91  ? 23.02600 32.81700 -9.33500  1.000 49.20000  ? 89  ARG A HB3  1 
ATOM   1370 H HG2  . ARG A 1 91  ? 24.32900 30.33400 -9.06700  1.000 58.74000  ? 89  ARG A HG2  1 
ATOM   1371 H HG3  . ARG A 1 91  ? 23.73000 30.81500 -10.46100 1.000 58.74000  ? 89  ARG A HG3  1 
ATOM   1372 H HD2  . ARG A 1 91  ? 25.31600 32.30800 -10.76500 1.000 60.60000  ? 89  ARG A HD2  1 
ATOM   1373 H HD3  . ARG A 1 91  ? 25.52400 32.54700 -9.20900  1.000 60.60000  ? 89  ARG A HD3  1 
ATOM   1374 H HE   . ARG A 1 91  ? 27.09600 31.03400 -9.24700  1.000 60.15000  ? 89  ARG A HE   1 
ATOM   1375 H HH11 . ARG A 1 91  ? 25.40500 30.58800 -12.07400 1.000 69.67000  ? 89  ARG A HH11 1 
ATOM   1376 H HH12 . ARG A 1 91  ? 26.32300 29.55900 -12.63300 1.000 69.67000  ? 89  ARG A HH12 1 
ATOM   1377 H HH21 . ARG A 1 91  ? 28.44800 29.46100 -10.11900 1.000 60.05000  ? 89  ARG A HH21 1 
ATOM   1378 H HH22 . ARG A 1 91  ? 28.15700 28.87800 -11.45600 1.000 60.05000  ? 89  ARG A HH22 1 
ATOM   1379 N N    . PRO A 1 92  ? 23.12400 34.62800 -7.11300  1.000 43.88000  ? 90  PRO A N    1 
ATOM   1380 C CA   . PRO A 1 92  ? 22.39000 35.80700 -6.61100  1.000 38.12000  ? 90  PRO A CA   1 
ATOM   1381 C C    . PRO A 1 92  ? 20.95900 35.89600 -7.11500  1.000 40.11000  ? 90  PRO A C    1 
ATOM   1382 O O    . PRO A 1 92  ? 20.13100 36.56100 -6.47500  1.000 46.08000  ? 90  PRO A O    1 
ATOM   1383 C CB   . PRO A 1 92  ? 23.23600 36.99000 -7.10800  1.000 46.32000  ? 90  PRO A CB   1 
ATOM   1384 C CG   . PRO A 1 92  ? 24.62100 36.41600 -7.26700  1.000 45.14000  ? 90  PRO A CG   1 
ATOM   1385 C CD   . PRO A 1 92  ? 24.41600 34.99300 -7.72800  1.000 51.14000  ? 90  PRO A CD   1 
ATOM   1386 H HA   . PRO A 1 92  ? 22.38400 35.80700 -5.64100  1.000 45.60000  ? 90  PRO A HA   1 
ATOM   1387 H HB2  . PRO A 1 92  ? 22.89300 37.30600 -7.95900  1.000 55.43000  ? 90  PRO A HB2  1 
ATOM   1388 H HB3  . PRO A 1 92  ? 23.23000 37.70000 -6.44700  1.000 55.43000  ? 90  PRO A HB3  1 
ATOM   1389 H HG2  . PRO A 1 92  ? 25.11000 36.92400 -7.93300  1.000 54.03000  ? 90  PRO A HG2  1 
ATOM   1390 H HG3  . PRO A 1 92  ? 25.08200 36.43600 -6.41400  1.000 54.03000  ? 90  PRO A HG3  1 
ATOM   1391 H HD2  . PRO A 1 92  ? 24.35500 34.95600 -8.69600  1.000 61.22000  ? 90  PRO A HD2  1 
ATOM   1392 H HD3  . PRO A 1 92  ? 25.13000 34.43000 -7.39200  1.000 61.22000  ? 90  PRO A HD3  1 
ATOM   1393 N N    . THR A 1 93  ? 20.64100 35.25300 -8.24100  1.000 36.50000  ? 91  THR A N    1 
ATOM   1394 C CA   . THR A 1 93  ? 19.26500 35.15600 -8.69500  1.000 39.07000  ? 91  THR A CA   1 
ATOM   1395 C C    . THR A 1 93  ? 18.41500 34.28000 -7.78700  1.000 42.97000  ? 91  THR A C    1 
ATOM   1396 O O    . THR A 1 93  ? 17.19100 34.22800 -7.96300  1.000 37.57000  ? 91  THR A O    1 
ATOM   1397 C CB   . THR A 1 93  ? 19.21500 34.57900 -10.10900 1.000 41.34000  ? 91  THR A CB   1 
ATOM   1398 O OG1  . THR A 1 93  ? 19.66900 33.21700 -10.07500 1.000 43.96000  ? 91  THR A OG1  1 
ATOM   1399 C CG2  . THR A 1 93  ? 20.09200 35.38200 -11.06000 1.000 41.14000  ? 91  THR A CG2  1 
ATOM   1400 H H    . THR A 1 93  ? 21.21000 34.86400 -8.75500  1.000 43.65000  ? 91  THR A H    1 
ATOM   1401 H HA   . THR A 1 93  ? 18.87300 36.04300 -8.71500  1.000 46.74000  ? 91  THR A HA   1 
ATOM   1402 H HB   . THR A 1 93  ? 18.30200 34.60700 -10.43700 1.000 49.46000  ? 91  THR A HB   1 
ATOM   1403 H HG1  . THR A 1 93  ? 19.64600 32.88700 -10.84700 1.000 52.61000  ? 91  THR A HG1  1 
ATOM   1404 H HG21 . THR A 1 93  ? 19.95000 35.08500 -11.97200 1.000 49.22000  ? 91  THR A HG21 1 
ATOM   1405 H HG22 . THR A 1 93  ? 19.87200 36.32500 -10.99700 1.000 49.22000  ? 91  THR A HG22 1 
ATOM   1406 H HG23 . THR A 1 93  ? 21.02700 35.26100 -10.83300 1.000 49.22000  ? 91  THR A HG23 1 
ATOM   1407 N N    . GLY A 1 94  ? 19.03700 33.57900 -6.83800  1.000 45.08000  ? 92  GLY A N    1 
ATOM   1408 C CA   . GLY A 1 94  ? 18.34900 32.61700 -6.01200  1.000 45.38000  ? 92  GLY A CA   1 
ATOM   1409 C C    . GLY A 1 94  ? 18.34600 31.20700 -6.55100  1.000 44.34000  ? 92  GLY A C    1 
ATOM   1410 O O    . GLY A 1 94  ? 17.93100 30.28700 -5.83100  1.000 43.85000  ? 92  GLY A O    1 
ATOM   1411 H H    . GLY A 1 94  ? 19.87300 33.64800 -6.65700  1.000 53.95000  ? 92  GLY A H    1 
ATOM   1412 H HA2  . GLY A 1 94  ? 18.76500 32.60000 -5.13600  1.000 54.31000  ? 92  GLY A HA2  1 
ATOM   1413 H HA3  . GLY A 1 94  ? 17.42700 32.89700 -5.90200  1.000 54.31000  ? 92  GLY A HA3  1 
ATOM   1414 N N    . GLU A 1 95  ? 18.79700 31.00100 -7.78400  1.000 38.14000  ? 93  GLU A N    1 
ATOM   1415 C CA   . GLU A 1 95  ? 18.75000 29.67000 -8.37000  1.000 35.19000  ? 93  GLU A CA   1 
ATOM   1416 C C    . GLU A 1 95  ? 19.67500 28.72600 -7.61500  1.000 43.54000  ? 93  GLU A C    1 
ATOM   1417 O O    . GLU A 1 95  ? 20.77600 29.10100 -7.20300  1.000 38.66000  ? 93  GLU A O    1 
ATOM   1418 C CB   . GLU A 1 95  ? 19.14300 29.71000 -9.84800  1.000 46.64000  ? 93  GLU A CB   1 
ATOM   1419 C CG   . GLU A 1 95  ? 18.53700 28.57300 -10.66900 1.000 54.72000  ? 93  GLU A CG   1 
ATOM   1420 C CD   . GLU A 1 95  ? 19.11500 28.48000 -12.06700 1.000 61.60000  ? 93  GLU A CD   1 
ATOM   1421 O OE1  . GLU A 1 95  ? 20.33700 28.69100 -12.22600 1.000 72.96000  ? 93  GLU A OE1  1 
ATOM   1422 O OE2  . GLU A 1 95  ? 18.34400 28.19300 -13.00900 1.000 72.63000  ? 93  GLU A OE2  1 
ATOM   1423 H H    . GLU A 1 95  ? 19.13100 31.60700 -8.29400  1.000 45.62000  ? 93  GLU A H    1 
ATOM   1424 H HA   . GLU A 1 95  ? 17.84600 29.32500 -8.30600  1.000 42.08000  ? 93  GLU A HA   1 
ATOM   1425 H HB2  . GLU A 1 95  ? 18.83900 30.54800 -10.23100 1.000 55.82000  ? 93  GLU A HB2  1 
ATOM   1426 H HB3  . GLU A 1 95  ? 20.10800 29.64600 -9.91800  1.000 55.82000  ? 93  GLU A HB3  1 
ATOM   1427 H HG2  . GLU A 1 95  ? 18.70900 27.73200 -10.21800 1.000 65.52000  ? 93  GLU A HG2  1 
ATOM   1428 H HG3  . GLU A 1 95  ? 17.58100 28.71700 -10.74900 1.000 65.52000  ? 93  GLU A HG3  1 
ATOM   1429 N N    . LEU A 1 96  ? 19.21100 27.49500 -7.43400  1.000 41.99000  ? 94  LEU A N    1 
ATOM   1430 C CA   . LEU A 1 96  ? 19.97700 26.44000 -6.78900  1.000 38.87000  ? 94  LEU A CA   1 
ATOM   1431 C C    . LEU A 1 96  ? 20.64200 25.60600 -7.87400  1.000 44.14000  ? 94  LEU A C    1 
ATOM   1432 O O    . LEU A 1 96  ? 19.95200 25.01900 -8.71400  1.000 44.02000  ? 94  LEU A O    1 
ATOM   1433 C CB   . LEU A 1 96  ? 19.07000 25.56700 -5.92500  1.000 43.73000  ? 94  LEU A CB   1 
ATOM   1434 C CG   . LEU A 1 96  ? 18.04200 26.32900 -5.09100  1.000 44.56000  ? 94  LEU A CG   1 
ATOM   1435 C CD1  . LEU A 1 96  ? 17.22500 25.38000 -4.23000  1.000 38.89000  ? 94  LEU A CD1  1 
ATOM   1436 C CD2  . LEU A 1 96  ? 18.74000 27.38300 -4.22600  1.000 44.07000  ? 94  LEU A CD2  1 
ATOM   1437 H H    . LEU A 1 96  ? 18.42900 27.24100 -7.68500  1.000 50.24000  ? 94  LEU A H    1 
ATOM   1438 H HA   . LEU A 1 96  ? 20.66600 26.82700 -6.22600  1.000 46.50000  ? 94  LEU A HA   1 
ATOM   1439 H HB2  . LEU A 1 96  ? 18.58400 24.96100 -6.50500  1.000 52.33000  ? 94  LEU A HB2  1 
ATOM   1440 H HB3  . LEU A 1 96  ? 19.62400 25.05800 -5.31300  1.000 52.33000  ? 94  LEU A HB3  1 
ATOM   1441 H HG   . LEU A 1 96  ? 17.43000 26.79000 -5.68700  1.000 53.32000  ? 94  LEU A HG   1 
ATOM   1442 H HD11 . LEU A 1 96  ? 16.62100 25.89800 -3.67500  1.000 46.52000  ? 94  LEU A HD11 1 
ATOM   1443 H HD12 . LEU A 1 96  ? 16.72000 24.78700 -4.80700  1.000 46.52000  ? 94  LEU A HD12 1 
ATOM   1444 H HD13 . LEU A 1 96  ? 17.82700 24.86400 -3.67200  1.000 46.52000  ? 94  LEU A HD13 1 
ATOM   1445 H HD21 . LEU A 1 96  ? 18.09700 27.75600 -3.60300  1.000 52.74000  ? 94  LEU A HD21 1 
ATOM   1446 H HD22 . LEU A 1 96  ? 19.46500 26.96200 -3.74000  1.000 52.74000  ? 94  LEU A HD22 1 
ATOM   1447 H HD23 . LEU A 1 96  ? 19.08900 28.08300 -4.79900  1.000 52.74000  ? 94  LEU A HD23 1 
ATOM   1448 N N    . MET A 1 97  ? 21.97600 25.54900 -7.85000  1.000 43.57000  ? 95  MET A N    1 
ATOM   1449 C CA   . MET A 1 97  ? 22.75200 24.82600 -8.85900  1.000 48.13000  ? 95  MET A CA   1 
ATOM   1450 C C    . MET A 1 97  ? 23.65700 23.80900 -8.19400  1.000 45.61000  ? 95  MET A C    1 
ATOM   1451 O O    . MET A 1 97  ? 24.82900 24.09100 -7.90500  1.000 41.30000  ? 95  MET A O    1 
ATOM   1452 C CB   . MET A 1 97  ? 23.58000 25.80000 -9.71000  1.000 47.65000  ? 95  MET A CB   1 
ATOM   1453 C CG   . MET A 1 97  ? 22.78100 26.91500 -10.36500 1.000 56.91000  ? 95  MET A CG   1 
ATOM   1454 S SD   . MET A 1 97  ? 23.61800 27.70500 -11.76800 1.000 89.70000  ? 95  MET A SD   1 
ATOM   1455 C CE   . MET A 1 97  ? 25.32200 27.16500 -11.57000 1.000 49.81000  ? 95  MET A CE   1 
ATOM   1456 H H    . MET A 1 97  ? 22.46100 25.92700 -7.25000  1.000 52.14000  ? 95  MET A H    1 
ATOM   1457 H HA   . MET A 1 97  ? 22.14300 24.36900 -9.45900  1.000 57.61000  ? 95  MET A HA   1 
ATOM   1458 H HB2  . MET A 1 97  ? 24.26000 26.20800 -9.15100  1.000 57.03000  ? 95  MET A HB2  1 
ATOM   1459 H HB3  . MET A 1 97  ? 23.99600 25.27800 -10.41200 1.000 57.03000  ? 95  MET A HB3  1 
ATOM   1460 H HG2  . MET A 1 97  ? 21.94300 26.54900 -10.68900 1.000 68.14000  ? 95  MET A HG2  1 
ATOM   1461 H HG3  . MET A 1 97  ? 22.60400 27.60200 -9.70200  1.000 68.14000  ? 95  MET A HG3  1 
ATOM   1462 H HE1  . MET A 1 97  ? 25.87500 27.62100 -12.22100 1.000 59.62000  ? 95  MET A HE1  1 
ATOM   1463 H HE2  . MET A 1 97  ? 25.62200 27.38000 -10.67300 1.000 59.62000  ? 95  MET A HE2  1 
ATOM   1464 H HE3  . MET A 1 97  ? 25.37600 26.20900 -11.72000 1.000 59.62000  ? 95  MET A HE3  1 
ATOM   1465 N N    . PRO A 1 98  ? 23.16500 22.58800 -7.94000  1.000 41.62000  ? 96  PRO A N    1 
ATOM   1466 C CA   . PRO A 1 98  ? 24.04900 21.52000 -7.45400  1.000 45.85000  ? 96  PRO A CA   1 
ATOM   1467 C C    . PRO A 1 98  ? 24.92800 21.01200 -8.59300  1.000 50.56000  ? 96  PRO A C    1 
ATOM   1468 O O    . PRO A 1 98  ? 24.42100 20.57700 -9.62300  1.000 46.31000  ? 96  PRO A O    1 
ATOM   1469 C CB   . PRO A 1 98  ? 23.07200 20.44500 -6.96600  1.000 48.18000  ? 96  PRO A CB   1 
ATOM   1470 C CG   . PRO A 1 98  ? 21.87200 20.62700 -7.83800  1.000 45.16000  ? 96  PRO A CG   1 
ATOM   1471 C CD   . PRO A 1 98  ? 21.79200 22.10600 -8.18600  1.000 43.24000  ? 96  PRO A CD   1 
ATOM   1472 H HA   . PRO A 1 98  ? 24.60000 21.83000 -6.71800  1.000 54.87000  ? 96  PRO A HA   1 
ATOM   1473 H HB2  . PRO A 1 98  ? 23.46000 19.56500 -7.08900  1.000 57.67000  ? 96  PRO A HB2  1 
ATOM   1474 H HB3  . PRO A 1 98  ? 22.84900 20.59900 -6.03400  1.000 57.67000  ? 96  PRO A HB3  1 
ATOM   1475 H HG2  . PRO A 1 98  ? 21.97700 20.09600 -8.64300  1.000 54.05000  ? 96  PRO A HG2  1 
ATOM   1476 H HG3  . PRO A 1 98  ? 21.07800 20.35100 -7.35300  1.000 54.05000  ? 96  PRO A HG3  1 
ATOM   1477 H HD2  . PRO A 1 98  ? 21.55500 22.21900 -9.11900  1.000 51.74000  ? 96  PRO A HD2  1 
ATOM   1478 H HD3  . PRO A 1 98  ? 21.16500 22.55800 -7.60000  1.000 51.74000  ? 96  PRO A HD3  1 
ATOM   1479 N N    . LEU A 1 99  ? 26.24500 21.07900 -8.39300  1.000 37.34000  ? 97  LEU A N    1 
ATOM   1480 C CA   . LEU A 1 99  ? 27.20800 20.66900 -9.40900  1.000 39.94000  ? 97  LEU A CA   1 
ATOM   1481 C C    . LEU A 1 99  ? 27.96400 19.44200 -8.92000  1.000 42.42000  ? 97  LEU A C    1 
ATOM   1482 O O    . LEU A 1 99  ? 28.66200 19.50300 -7.90300  1.000 42.19000  ? 97  LEU A O    1 
ATOM   1483 C CB   . LEU A 1 99  ? 28.18400 21.80000 -9.72200  1.000 43.02000  ? 97  LEU A CB   1 
ATOM   1484 C CG   . LEU A 1 99  ? 27.59700 23.09200 -10.28800 1.000 42.57000  ? 97  LEU A CG   1 
ATOM   1485 C CD1  . LEU A 1 99  ? 28.71700 24.05600 -10.65500 1.000 46.99000  ? 97  LEU A CD1  1 
ATOM   1486 C CD2  . LEU A 1 99  ? 26.73100 22.79900 -11.49500 1.000 43.42000  ? 97  LEU A CD2  1 
ATOM   1487 H H    . LEU A 1 99  ? 26.60800 21.36300 -7.66700  1.000 44.67000  ? 97  LEU A H    1 
ATOM   1488 H HA   . LEU A 1 99  ? 26.74000 20.43100 -10.22400 1.000 47.78000  ? 97  LEU A HA   1 
ATOM   1489 H HB2  . LEU A 1 99  ? 28.64800 22.03300 -8.90300  1.000 51.48000  ? 97  LEU A HB2  1 
ATOM   1490 H HB3  . LEU A 1 99  ? 28.82700 21.47100 -10.37000 1.000 51.48000  ? 97  LEU A HB3  1 
ATOM   1491 H HG   . LEU A 1 99  ? 27.04400 23.51300 -9.61200  1.000 50.94000  ? 97  LEU A HG   1 
ATOM   1492 H HD11 . LEU A 1 99  ? 28.32800 24.87000 -11.01000 1.000 56.24000  ? 97  LEU A HD11 1 
ATOM   1493 H HD12 . LEU A 1 99  ? 29.23400 24.25500 -9.86000  1.000 56.24000  ? 97  LEU A HD12 1 
ATOM   1494 H HD13 . LEU A 1 99  ? 29.28400 23.64100 -11.32400 1.000 56.24000  ? 97  LEU A HD13 1 
ATOM   1495 H HD21 . LEU A 1 99  ? 26.49800 23.63600 -11.92600 1.000 51.96000  ? 97  LEU A HD21 1 
ATOM   1496 H HD22 . LEU A 1 99  ? 27.22700 22.23600 -12.11000 1.000 51.96000  ? 97  LEU A HD22 1 
ATOM   1497 H HD23 . LEU A 1 99  ? 25.92600 22.34200 -11.20400 1.000 51.96000  ? 97  LEU A HD23 1 
ATOM   1498 N N    . ALA A 1 100 ? 27.83400 18.33400 -9.64600  1.000 42.64000  ? 98  ALA A N    1 
ATOM   1499 C CA   . ALA A 1 100 ? 28.56300 17.12500 -9.28900  1.000 44.68000  ? 98  ALA A CA   1 
ATOM   1500 C C    . ALA A 1 100 ? 30.05300 17.32300 -9.54700  1.000 39.60000  ? 98  ALA A C    1 
ATOM   1501 O O    . ALA A 1 100 ? 30.45400 17.91400 -10.55600 1.000 40.37000  ? 98  ALA A O    1 
ATOM   1502 C CB   . ALA A 1 100 ? 28.03900 15.93200 -10.08300 1.000 44.03000  ? 98  ALA A CB   1 
ATOM   1503 H H    . ALA A 1 100 ? 27.33600 18.25900 -10.34200 1.000 51.02000  ? 98  ALA A H    1 
ATOM   1504 H HA   . ALA A 1 100 ? 28.43900 16.94200 -8.34500  1.000 53.47000  ? 98  ALA A HA   1 
ATOM   1505 H HB1  . ALA A 1 100 ? 28.53400 15.13800 -9.82300  1.000 52.69000  ? 98  ALA A HB1  1 
ATOM   1506 H HB2  . ALA A 1 100 ? 27.09600 15.81300 -9.88900  1.000 52.69000  ? 98  ALA A HB2  1 
ATOM   1507 H HB3  . ALA A 1 100 ? 28.16300 16.10400 -11.03000 1.000 52.69000  ? 98  ALA A HB3  1 
ATOM   1508 N N    . ALA A 1 101 ? 30.87700 16.83700 -8.62200  1.000 43.04000  ? 99  ALA A N    1 
ATOM   1509 C CA   . ALA A 1 101 ? 32.32400 16.95500 -8.74200  1.000 44.29000  ? 99  ALA A CA   1 
ATOM   1510 C C    . ALA A 1 101 ? 32.98800 15.71700 -8.16100  1.000 46.61000  ? 99  ALA A C    1 
ATOM   1511 O O    . ALA A 1 101 ? 32.74100 15.35300 -7.00700  1.000 39.61000  ? 99  ALA A O    1 
ATOM   1512 C CB   . ALA A 1 101 ? 32.84400 18.21100 -8.02700  1.000 40.88000  ? 99  ALA A CB   1 
ATOM   1513 H H    . ALA A 1 101 ? 30.61800 16.43000 -7.90900  1.000 51.50000  ? 99  ALA A H    1 
ATOM   1514 H HA   . ALA A 1 101 ? 32.56000 17.01900 -9.67900  1.000 53.00000  ? 99  ALA A HA   1 
ATOM   1515 H HB1  . ALA A 1 101 ? 33.80700 18.25700 -8.13100  1.000 48.91000  ? 99  ALA A HB1  1 
ATOM   1516 H HB2  . ALA A 1 101 ? 32.43000 18.99400 -8.42300  1.000 48.91000  ? 99  ALA A HB2  1 
ATOM   1517 H HB3  . ALA A 1 101 ? 32.61400 18.15600 -7.08600  1.000 48.91000  ? 99  ALA A HB3  1 
ATOM   1518 N N    . ARG A 1 102 ? 33.82400 15.07100 -8.96900  1.000 42.70000  ? 100 ARG A N    1 
ATOM   1519 C CA   . ARG A 1 102 ? 34.62100 13.94500 -8.50600  1.000 40.11000  ? 100 ARG A CA   1 
ATOM   1520 C C    . ARG A 1 102 ? 35.83200 14.50000 -7.76500  1.000 38.93000  ? 100 ARG A C    1 
ATOM   1521 O O    . ARG A 1 102 ? 36.64700 15.22100 -8.35400  1.000 36.16000  ? 100 ARG A O    1 
ATOM   1522 C CB   . ARG A 1 102 ? 35.04400 13.07100 -9.68000  1.000 38.05000  ? 100 ARG A CB   1 
ATOM   1523 C CG   . ARG A 1 102 ? 35.90000 11.87700 -9.28100  1.000 50.63000  ? 100 ARG A CG   1 
ATOM   1524 C CD   . ARG A 1 102 ? 36.06300 10.88800 -10.43800 1.000 49.96000  ? 100 ARG A CD   1 
ATOM   1525 N NE   . ARG A 1 102 ? 34.89200 10.03200 -10.58100 1.000 61.22000  ? 100 ARG A NE   1 
ATOM   1526 C CZ   . ARG A 1 102 ? 34.14500 9.95000  -11.67400 1.000 69.36000  ? 100 ARG A CZ   1 
ATOM   1527 N NH1  . ARG A 1 102 ? 34.44300 10.63400 -12.77000 1.000 65.80000  ? 100 ARG A NH1  1 
ATOM   1528 N NH2  . ARG A 1 102 ? 33.07200 9.16200  -11.67000 1.000 64.31000  ? 100 ARG A NH2  1 
ATOM   1529 H H    . ARG A 1 102 ? 33.94600 15.27000 -9.79600  1.000 51.10000  ? 100 ARG A H    1 
ATOM   1530 H HA   . ARG A 1 102 ? 34.10000 13.40700 -7.89000  1.000 47.98000  ? 100 ARG A HA   1 
ATOM   1531 H HB2  . ARG A 1 102 ? 34.24800 12.73200 -10.11900 1.000 45.51000  ? 100 ARG A HB2  1 
ATOM   1532 H HB3  . ARG A 1 102 ? 35.55800 13.61100 -10.30100 1.000 45.51000  ? 100 ARG A HB3  1 
ATOM   1533 H HG2  . ARG A 1 102 ? 36.78200 12.18800 -9.02100  1.000 60.61000  ? 100 ARG A HG2  1 
ATOM   1534 H HG3  . ARG A 1 102 ? 35.47700 11.41300 -8.54200  1.000 60.61000  ? 100 ARG A HG3  1 
ATOM   1535 H HD2  . ARG A 1 102 ? 36.21000 11.38700 -11.25400 1.000 59.80000  ? 100 ARG A HD2  1 
ATOM   1536 H HD3  . ARG A 1 102 ? 36.82700 10.31900 -10.25800 1.000 59.80000  ? 100 ARG A HD3  1 
ATOM   1537 H HE   . ARG A 1 102 ? 34.53000 9.76000  -9.85200  1.000 73.32000  ? 100 ARG A HE   1 
ATOM   1538 H HH11 . ARG A 1 102 ? 35.12900 11.14900 -12.79500 1.000 78.81000  ? 100 ARG A HH11 1 
ATOM   1539 H HH12 . ARG A 1 102 ? 33.94200 10.56200 -13.46500 1.000 78.81000  ? 100 ARG A HH12 1 
ATOM   1540 H HH21 . ARG A 1 102 ? 32.87000 8.71300  -10.96400 1.000 77.02000  ? 100 ARG A HH21 1 
ATOM   1541 H HH22 . ARG A 1 102 ? 32.58200 9.10000  -12.37400 1.000 77.02000  ? 100 ARG A HH22 1 
ATOM   1542 N N    . MET A 1 103 ? 35.93600 14.18600 -6.47700  1.000 37.09000  ? 101 MET A N    1 
ATOM   1543 C CA   . MET A 1 103 ? 36.99400 14.74100 -5.64600  1.000 38.50000  ? 101 MET A CA   1 
ATOM   1544 C C    . MET A 1 103 ? 38.27900 13.94000 -5.81600  1.000 41.47000  ? 101 MET A C    1 
ATOM   1545 O O    . MET A 1 103 ? 38.26400 12.70500 -5.82100  1.000 44.05000  ? 101 MET A O    1 
ATOM   1546 C CB   . MET A 1 103 ? 36.56800 14.74900 -4.18000  1.000 36.70000  ? 101 MET A CB   1 
ATOM   1547 C CG   . MET A 1 103 ? 35.28500 15.52400 -3.91400  1.000 40.77000  ? 101 MET A CG   1 
ATOM   1548 S SD   . MET A 1 103 ? 35.29500 17.19000 -4.61700  1.000 39.58000  ? 101 MET A SD   1 
ATOM   1549 C CE   . MET A 1 103 ? 36.75300 17.89000 -3.84400  1.000 37.68000  ? 101 MET A CE   1 
ATOM   1550 H H    . MET A 1 103 ? 35.40300 13.65300 -6.06100  1.000 44.37000  ? 101 MET A H    1 
ATOM   1551 H HA   . MET A 1 103 ? 37.16300 15.65600 -5.91800  1.000 46.05000  ? 101 MET A HA   1 
ATOM   1552 H HB2  . MET A 1 103 ? 36.42500 13.83400 -3.89200  1.000 43.89000  ? 101 MET A HB2  1 
ATOM   1553 H HB3  . MET A 1 103 ? 37.27400 15.15300 -3.65100  1.000 43.89000  ? 101 MET A HB3  1 
ATOM   1554 H HG2  . MET A 1 103 ? 34.54000 15.04100 -4.30300  1.000 48.77000  ? 101 MET A HG2  1 
ATOM   1555 H HG3  . MET A 1 103 ? 35.16100 15.60600 -2.95600  1.000 48.77000  ? 101 MET A HG3  1 
ATOM   1556 H HE1  . MET A 1 103 ? 36.82800 18.82300 -4.09900  1.000 45.07000  ? 101 MET A HE1  1 
ATOM   1557 H HE2  . MET A 1 103 ? 36.66500 17.81700 -2.88100  1.000 45.07000  ? 101 MET A HE2  1 
ATOM   1558 H HE3  . MET A 1 103 ? 37.53500 17.40100 -4.14200  1.000 45.07000  ? 101 MET A HE3  1 
ATOM   1559 N N    . GLY A 1 104 ? 39.39600 14.65500 -5.94700  1.000 42.83000  ? 102 GLY A N    1 
ATOM   1560 C CA   . GLY A 1 104 ? 40.68200 14.03500 -6.20500  1.000 41.42000  ? 102 GLY A CA   1 
ATOM   1561 C C    . GLY A 1 104 ? 41.64500 14.12000 -5.04100  1.000 36.74000  ? 102 GLY A C    1 
ATOM   1562 O O    . GLY A 1 104 ? 41.27300 13.83200 -3.90000  1.000 37.15000  ? 102 GLY A O    1 
ATOM   1563 H H    . GLY A 1 104 ? 39.42900 15.51200 -5.88700  1.000 51.25000  ? 102 GLY A H    1 
ATOM   1564 H HA2  . GLY A 1 104 ? 40.55100 13.10000 -6.42300  1.000 49.55000  ? 102 GLY A HA2  1 
ATOM   1565 H HA3  . GLY A 1 104 ? 41.09400 14.46900 -6.96900  1.000 49.55000  ? 102 GLY A HA3  1 
ATOM   1566 N N    . THR A 1 105 ? 42.88300 14.52100 -5.30600  1.000 36.71000  ? 103 THR A N    1 
ATOM   1567 C CA   . THR A 1 105 ? 43.91800 14.42500 -4.29000  1.000 38.31000  ? 103 THR A CA   1 
ATOM   1568 C C    . THR A 1 105 ? 43.82800 15.57300 -3.29600  1.000 37.00000  ? 103 THR A C    1 
ATOM   1569 O O    . THR A 1 105 ? 43.48900 16.70500 -3.65500  1.000 37.87000  ? 103 THR A O    1 
ATOM   1570 C CB   . THR A 1 105 ? 45.31600 14.41200 -4.91300  1.000 45.55000  ? 103 THR A CB   1 
ATOM   1571 O OG1  . THR A 1 105 ? 45.72700 15.74500 -5.21600  1.000 56.13000  ? 103 THR A OG1  1 
ATOM   1572 C CG2  . THR A 1 105 ? 45.33900 13.59400 -6.18100  1.000 34.13000  ? 103 THR A CG2  1 
ATOM   1573 H H    . THR A 1 105 ? 43.14200 14.85400 -6.05400  1.000 43.91000  ? 103 THR A H    1 
ATOM   1574 H HA   . THR A 1 105 ? 43.80200 13.59600 -3.80100  1.000 45.82000  ? 103 THR A HA   1 
ATOM   1575 H HB   . THR A 1 105 ? 45.94300 14.01900 -4.28600  1.000 54.52000  ? 103 THR A HB   1 
ATOM   1576 H HG1  . THR A 1 105 ? 46.49600 15.73800 -5.55600  1.000 67.20000  ? 103 THR A HG1  1 
ATOM   1577 H HG21 . THR A 1 105 ? 46.25500 13.44000 -6.46500  1.000 40.81000  ? 103 THR A HG21 1 
ATOM   1578 H HG22 . THR A 1 105 ? 44.90000 12.74100 -6.03800  1.000 40.81000  ? 103 THR A HG22 1 
ATOM   1579 H HG23 . THR A 1 105 ? 44.87100 14.08200 -6.86800  1.000 40.81000  ? 103 THR A HG23 1 
ATOM   1580 N N    . HIS A 1 106 ? 44.10500 15.25700 -2.03300  1.000 37.94000  ? 104 HIS A N    1 
ATOM   1581 C CA   . HIS A 1 106 ? 44.36100 16.26100 -1.01600  1.000 40.40000  ? 104 HIS A CA   1 
ATOM   1582 C C    . HIS A 1 106 ? 45.79700 16.72800 -1.19100  1.000 41.89000  ? 104 HIS A C    1 
ATOM   1583 O O    . HIS A 1 106 ? 46.70400 15.90700 -1.35900  1.000 37.20000  ? 104 HIS A O    1 
ATOM   1584 C CB   . HIS A 1 106 ? 44.16400 15.69300 0.38700   1.000 36.27000  ? 104 HIS A CB   1 
ATOM   1585 C CG   . HIS A 1 106 ? 42.82700 15.05700 0.61000   1.000 40.84000  ? 104 HIS A CG   1 
ATOM   1586 N ND1  . HIS A 1 106 ? 42.01500 15.39000 1.67200   1.000 40.73000  ? 104 HIS A ND1  1 
ATOM   1587 C CD2  . HIS A 1 106 ? 42.17500 14.08400 -0.07200  1.000 43.73000  ? 104 HIS A CD2  1 
ATOM   1588 C CE1  . HIS A 1 106 ? 40.91200 14.66200 1.62700   1.000 37.21000  ? 104 HIS A CE1  1 
ATOM   1589 N NE2  . HIS A 1 106 ? 40.98300 13.86400 0.57800   1.000 48.33000  ? 104 HIS A NE2  1 
ATOM   1590 H H    . HIS A 1 106 ? 44.15400 14.45000 -1.74000  1.000 45.38000  ? 104 HIS A H    1 
ATOM   1591 H HA   . HIS A 1 106 ? 43.76500 17.01700 -1.13800  1.000 48.34000  ? 104 HIS A HA   1 
ATOM   1592 H HB2  . HIS A 1 106 ? 44.84200 15.01800 0.54700   1.000 43.38000  ? 104 HIS A HB2  1 
ATOM   1593 H HB3  . HIS A 1 106 ? 44.25900 16.41300 1.03100   1.000 43.38000  ? 104 HIS A HB3  1 
ATOM   1594 H HD2  . HIS A 1 106 ? 42.47300 13.65400 -0.84100  1.000 52.33000  ? 104 HIS A HD2  1 
ATOM   1595 H HE1  . HIS A 1 106 ? 40.20600 14.70600 2.23000   1.000 44.50000  ? 104 HIS A HE1  1 
ATOM   1596 H HE2  . HIS A 1 106 ? 40.38200 13.29600 0.34000   1.000 57.85000  ? 104 HIS A HE2  1 
ATOM   1597 N N    . ALA A 1 107 ? 46.00900 18.03600 -1.16300  1.000 37.20000  ? 105 ALA A N    1 
ATOM   1598 C CA   . ALA A 1 107 ? 47.36900 18.53300 -1.29600  1.000 37.44000  ? 105 ALA A CA   1 
ATOM   1599 C C    . ALA A 1 107 ? 47.43500 19.96200 -0.79800  1.000 36.91000  ? 105 ALA A C    1 
ATOM   1600 O O    . ALA A 1 107 ? 46.42600 20.66200 -0.72400  1.000 41.04000  ? 105 ALA A O    1 
ATOM   1601 C CB   . ALA A 1 107 ? 47.85900 18.45600 -2.74700  1.000 36.87000  ? 105 ALA A CB   1 
ATOM   1602 H H    . ALA A 1 107 ? 45.40400 18.64000 -1.07200  1.000 44.49000  ? 105 ALA A H    1 
ATOM   1603 H HA   . ALA A 1 107 ? 47.96100 17.99400 -0.74800  1.000 44.78000  ? 105 ALA A HA   1 
ATOM   1604 H HB1  . ALA A 1 107 ? 48.76600 18.79600 -2.79100  1.000 44.09000  ? 105 ALA A HB1  1 
ATOM   1605 H HB2  . ALA A 1 107 ? 47.83700 17.53100 -3.03900  1.000 44.09000  ? 105 ALA A HB2  1 
ATOM   1606 H HB3  . ALA A 1 107 ? 47.27600 18.99400 -3.30500  1.000 44.09000  ? 105 ALA A HB3  1 
ATOM   1607 N N    . THR A 1 108 ? 48.64200 20.37100 -0.43900  1.000 39.56000  ? 106 THR A N    1 
ATOM   1608 C CA   . THR A 1 108 ? 48.97700 21.77500 -0.23400  1.000 40.59000  ? 106 THR A CA   1 
ATOM   1609 C C    . THR A 1 108 ? 49.34400 22.34900 -1.60000  1.000 42.72000  ? 106 THR A C    1 
ATOM   1610 O O    . THR A 1 108 ? 50.34700 21.94400 -2.20000  1.000 41.13000  ? 106 THR A O    1 
ATOM   1611 C CB   . THR A 1 108 ? 50.11800 21.92300 0.76400   1.000 39.98000  ? 106 THR A CB   1 
ATOM   1612 O OG1  . THR A 1 108 ? 49.71000 21.37300 2.02200   1.000 42.95000  ? 106 THR A OG1  1 
ATOM   1613 C CG2  . THR A 1 108 ? 50.49300 23.38600 0.92700   1.000 43.79000  ? 106 THR A CG2  1 
ATOM   1614 H H    . THR A 1 108 ? 49.30500 19.84000 -0.30300  1.000 47.32000  ? 106 THR A H    1 
ATOM   1615 H HA   . THR A 1 108 ? 48.20200 22.25000 0.10600   1.000 48.56000  ? 106 THR A HA   1 
ATOM   1616 H HB   . THR A 1 108 ? 50.89500 21.44200 0.44000   1.000 47.83000  ? 106 THR A HB   1 
ATOM   1617 H HG1  . THR A 1 108 ? 50.33000 21.44700 2.58300   1.000 51.39000  ? 106 THR A HG1  1 
ATOM   1618 H HG21 . THR A 1 108 ? 51.10400 23.48800 1.67400   1.000 52.40000  ? 106 THR A HG21 1 
ATOM   1619 H HG22 . THR A 1 108 ? 50.92500 23.71300 0.12200   1.000 52.40000  ? 106 THR A HG22 1 
ATOM   1620 H HG23 . THR A 1 108 ? 49.69700 23.91300 1.09700   1.000 52.40000  ? 106 THR A HG23 1 
ATOM   1621 N N    . MET A 1 109 ? 48.53800 23.29000 -2.08700  1.000 40.33000  ? 107 MET A N    1 
ATOM   1622 C CA   . MET A 1 109 ? 48.63700 23.75300 -3.45800  1.000 35.13000  ? 107 MET A CA   1 
ATOM   1623 C C    . MET A 1 109 ? 49.01700 25.22200 -3.51500  1.000 36.52000  ? 107 MET A C    1 
ATOM   1624 O O    . MET A 1 109 ? 48.71100 26.00000 -2.61100  1.000 38.31000  ? 107 MET A O    1 
ATOM   1625 C CB   . MET A 1 109 ? 47.31600 23.56000 -4.19900  1.000 42.39000  ? 107 MET A CB   1 
ATOM   1626 C CG   . MET A 1 109 ? 46.74200 22.16700 -4.10000  1.000 43.43000  ? 107 MET A CG   1 
ATOM   1627 S SD   . MET A 1 109 ? 45.07900 22.15200 -4.78000  1.000 51.40000  ? 107 MET A SD   1 
ATOM   1628 C CE   . MET A 1 109 ? 44.10200 22.15100 -3.28500  1.000 44.69000  ? 107 MET A CE   1 
ATOM   1629 H H    . MET A 1 109 ? 47.91900 23.67800 -1.63300  1.000 48.25000  ? 107 MET A H    1 
ATOM   1630 H HA   . MET A 1 109 ? 49.31400 23.23600 -3.91900  1.000 42.01000  ? 107 MET A HA   1 
ATOM   1631 H HB2  . MET A 1 109 ? 46.66100 24.17500 -3.83300  1.000 50.72000  ? 107 MET A HB2  1 
ATOM   1632 H HB3  . MET A 1 109 ? 47.45700 23.75400 -5.13900  1.000 50.72000  ? 107 MET A HB3  1 
ATOM   1633 H HG2  . MET A 1 109 ? 47.29000 21.55000 -4.61000  1.000 51.97000  ? 107 MET A HG2  1 
ATOM   1634 H HG3  . MET A 1 109 ? 46.69700 21.89600 -3.17000  1.000 51.97000  ? 107 MET A HG3  1 
ATOM   1635 H HE1  . MET A 1 109 ? 43.18300 21.93500 -3.50800  1.000 53.48000  ? 107 MET A HE1  1 
ATOM   1636 H HE2  . MET A 1 109 ? 44.45800 21.48500 -2.67700  1.000 53.48000  ? 107 MET A HE2  1 
ATOM   1637 H HE3  . MET A 1 109 ? 44.14900 23.03000 -2.87600  1.000 53.48000  ? 107 MET A HE3  1 
ATOM   1638 N N    . LYS A 1 110 ? 49.69700 25.59000 -4.59500  1.000 35.94000  ? 108 LYS A N    1 
ATOM   1639 C CA   . LYS A 1 110 ? 49.96100 26.99100 -4.90000  1.000 39.88000  ? 108 LYS A CA   1 
ATOM   1640 C C    . LYS A 1 110 ? 48.85700 27.47900 -5.82800  1.000 39.37000  ? 108 LYS A C    1 
ATOM   1641 O O    . LYS A 1 110 ? 48.58900 26.85700 -6.86300  1.000 37.39000  ? 108 LYS A O    1 
ATOM   1642 C CB   . LYS A 1 110 ? 51.33600 27.15200 -5.53500  1.000 43.63000  ? 108 LYS A CB   1 
ATOM   1643 C CG   . LYS A 1 110 ? 52.47100 27.28000 -4.52000  1.000 52.11000  ? 108 LYS A CG   1 
ATOM   1644 C CD   . LYS A 1 110 ? 53.37000 28.49400 -4.79800  1.000 73.25000  ? 108 LYS A CD   1 
ATOM   1645 C CE   . LYS A 1 110 ? 53.90600 28.52500 -6.23500  1.000 71.60000  ? 108 LYS A CE   1 
ATOM   1646 N NZ   . LYS A 1 110 ? 54.20400 29.92200 -6.69400  1.000 58.59000  ? 108 LYS A NZ   1 
ATOM   1647 H H    . LYS A 1 110 ? 50.01900 25.04100 -5.17300  1.000 42.98000  ? 108 LYS A H    1 
ATOM   1648 H HA   . LYS A 1 110 ? 49.93200 27.51300 -4.08500  1.000 47.70000  ? 108 LYS A HA   1 
ATOM   1649 H HB2  . LYS A 1 110 ? 51.51900 26.38100 -6.09500  1.000 52.21000  ? 108 LYS A HB2  1 
ATOM   1650 H HB3  . LYS A 1 110 ? 51.31700 27.95600 -6.07500  1.000 52.21000  ? 108 LYS A HB3  1 
ATOM   1651 H HG2  . LYS A 1 110 ? 52.09700 27.38100 -3.63100  1.000 62.38000  ? 108 LYS A HG2  1 
ATOM   1652 H HG3  . LYS A 1 110 ? 53.02200 26.48300 -4.56000  1.000 62.38000  ? 108 LYS A HG3  1 
ATOM   1653 H HD2  . LYS A 1 110 ? 52.85900 29.30500 -4.65200  1.000 87.75000  ? 108 LYS A HD2  1 
ATOM   1654 H HD3  . LYS A 1 110 ? 54.13000 28.46800 -4.19600  1.000 87.75000  ? 108 LYS A HD3  1 
ATOM   1655 H HE2  . LYS A 1 110 ? 54.73500 28.02100 -6.26700  1.000 85.77000  ? 108 LYS A HE2  1 
ATOM   1656 H HE3  . LYS A 1 110 ? 53.26900 28.14100 -6.85500  1.000 85.77000  ? 108 LYS A HE3  1 
ATOM   1657 H HZ1  . LYS A 1 110 ? 54.51200 29.90800 -7.52800  1.000 70.16000  ? 108 LYS A HZ1  1 
ATOM   1658 H HZ2  . LYS A 1 110 ? 53.46400 30.41500 -6.66700  1.000 70.16000  ? 108 LYS A HZ2  1 
ATOM   1659 H HZ3  . LYS A 1 110 ? 54.81700 30.29000 -6.16400  1.000 70.16000  ? 108 LYS A HZ3  1 
ATOM   1660 N N    . ILE A 1 111 ? 48.18600 28.55500 -5.43100  1.000 37.32000  ? 109 ILE A N    1 
ATOM   1661 C CA   . ILE A 1 111 ? 47.09500 29.15000 -6.19500  1.000 39.24000  ? 109 ILE A CA   1 
ATOM   1662 C C    . ILE A 1 111 ? 47.38100 30.64500 -6.27400  1.000 44.84000  ? 109 ILE A C    1 
ATOM   1663 O O    . ILE A 1 111 ? 47.30200 31.34900 -5.25800  1.000 43.23000  ? 109 ILE A O    1 
ATOM   1664 C CB   . ILE A 1 111 ? 45.72300 28.88600 -5.56000  1.000 40.87000  ? 109 ILE A CB   1 
ATOM   1665 C CG1  . ILE A 1 111 ? 45.48300 27.37700 -5.39800  1.000 38.73000  ? 109 ILE A CG1  1 
ATOM   1666 C CG2  . ILE A 1 111 ? 44.61900 29.52700 -6.39200  1.000 37.87000  ? 109 ILE A CG2  1 
ATOM   1667 C CD1  . ILE A 1 111 ? 45.41600 26.61700 -6.70700  1.000 51.83000  ? 109 ILE A CD1  1 
ATOM   1668 H H    . ILE A 1 111 ? 48.35100 28.97200 -4.69700  1.000 44.63000  ? 109 ILE A H    1 
ATOM   1669 H HA   . ILE A 1 111 ? 47.09500 28.79400 -7.09700  1.000 46.94000  ? 109 ILE A HA   1 
ATOM   1670 H HB   . ILE A 1 111 ? 45.71400 29.29000 -4.67900  1.000 48.90000  ? 109 ILE A HB   1 
ATOM   1671 H HG12 . ILE A 1 111 ? 46.20200 26.99600 -4.86900  1.000 46.33000  ? 109 ILE A HG12 1 
ATOM   1672 H HG13 . ILE A 1 111 ? 44.63600 27.24500 -4.94500  1.000 46.33000  ? 109 ILE A HG13 1 
ATOM   1673 H HG21 . ILE A 1 111 ? 43.76100 29.19900 -6.08100  1.000 45.29000  ? 109 ILE A HG21 1 
ATOM   1674 H HG22 . ILE A 1 111 ? 44.66100 30.49000 -6.28800  1.000 45.29000  ? 109 ILE A HG22 1 
ATOM   1675 H HG23 . ILE A 1 111 ? 44.74600 29.28700 -7.32300  1.000 45.29000  ? 109 ILE A HG23 1 
ATOM   1676 H HD11 . ILE A 1 111 ? 45.34300 25.66900 -6.51400  1.000 62.05000  ? 109 ILE A HD11 1 
ATOM   1677 H HD12 . ILE A 1 111 ? 44.63700 26.91200 -7.20200  1.000 62.05000  ? 109 ILE A HD12 1 
ATOM   1678 H HD13 . ILE A 1 111 ? 46.22000 26.78500 -7.22100  1.000 62.05000  ? 109 ILE A HD13 1 
ATOM   1679 N N    . GLN A 1 112 ? 47.73000 31.12600 -7.46600  1.000 46.46000  ? 110 GLN A N    1 
ATOM   1680 C CA   . GLN A 1 112 ? 48.09000 32.52900 -7.67800  1.000 45.73000  ? 110 GLN A CA   1 
ATOM   1681 C C    . GLN A 1 112 ? 49.13100 32.99600 -6.66000  1.000 45.16000  ? 110 GLN A C    1 
ATOM   1682 O O    . GLN A 1 112 ? 49.02800 34.07400 -6.07100  1.000 46.81000  ? 110 GLN A O    1 
ATOM   1683 C CB   . GLN A 1 112 ? 46.84700 33.41900 -7.63600  1.000 44.89000  ? 110 GLN A CB   1 
ATOM   1684 C CG   . GLN A 1 112 ? 45.81500 33.07400 -8.70000  1.000 51.45000  ? 110 GLN A CG   1 
ATOM   1685 C CD   . GLN A 1 112 ? 45.04000 34.27900 -9.19700  1.000 57.60000  ? 110 GLN A CD   1 
ATOM   1686 O OE1  . GLN A 1 112 ? 44.46800 35.04400 -8.41300  1.000 58.82000  ? 110 GLN A OE1  1 
ATOM   1687 N NE2  . GLN A 1 112 ? 44.99700 34.44300 -10.51500 1.000 68.89000  ? 110 GLN A NE2  1 
ATOM   1688 H H    . GLN A 1 112 ? 47.76800 30.65000 -8.18300  1.000 55.60000  ? 110 GLN A H    1 
ATOM   1689 H HA   . GLN A 1 112 ? 48.48300 32.61700 -8.56100  1.000 54.73000  ? 110 GLN A HA   1 
ATOM   1690 H HB2  . GLN A 1 112 ? 46.42200 33.32500 -6.76900  1.000 53.72000  ? 110 GLN A HB2  1 
ATOM   1691 H HB3  . GLN A 1 112 ? 47.11700 34.34100 -7.77300  1.000 53.72000  ? 110 GLN A HB3  1 
ATOM   1692 H HG2  . GLN A 1 112 ? 46.26800 32.67600 -9.46000  1.000 61.60000  ? 110 GLN A HG2  1 
ATOM   1693 H HG3  . GLN A 1 112 ? 45.17900 32.44400 -8.32700  1.000 61.60000  ? 110 GLN A HG3  1 
ATOM   1694 H HE21 . GLN A 1 112 ? 45.40400 33.88800 -11.03100 1.000 82.52000  ? 110 GLN A HE21 1 
ATOM   1695 H HE22 . GLN A 1 112 ? 44.56900 35.10900 -10.85100 1.000 82.52000  ? 110 GLN A HE22 1 
ATOM   1696 N N    . GLY A 1 113 ? 50.15600 32.16600 -6.45800  1.000 47.36000  ? 111 GLY A N    1 
ATOM   1697 C CA   . GLY A 1 113 ? 51.25800 32.49300 -5.58000  1.000 46.57000  ? 111 GLY A CA   1 
ATOM   1698 C C    . GLY A 1 113 ? 51.05600 32.13200 -4.12300  1.000 46.40000  ? 111 GLY A C    1 
ATOM   1699 O O    . GLY A 1 113 ? 52.04200 31.99500 -3.39000  1.000 45.17000  ? 111 GLY A O    1 
ATOM   1700 H H    . GLY A 1 113 ? 50.22900 31.39400 -6.83100  1.000 56.68000  ? 111 GLY A H    1 
ATOM   1701 H HA2  . GLY A 1 113 ? 52.05300 32.03400 -5.89200  1.000 55.74000  ? 111 GLY A HA2  1 
ATOM   1702 H HA3  . GLY A 1 113 ? 51.42600 33.44700 -5.62900  1.000 55.74000  ? 111 GLY A HA3  1 
ATOM   1703 N N    . ALA A 1 114 ? 49.81400 31.97000 -3.68200  1.000 44.91000  ? 112 ALA A N    1 
ATOM   1704 C CA   . ALA A 1 114 ? 49.52500 31.69600 -2.28600  1.000 44.68000  ? 112 ALA A CA   1 
ATOM   1705 C C    . ALA A 1 114 ? 49.40700 30.19600 -2.03800  1.000 47.41000  ? 112 ALA A C    1 
ATOM   1706 O O    . ALA A 1 114 ? 49.06100 29.41900 -2.93200  1.000 47.38000  ? 112 ALA A O    1 
ATOM   1707 C CB   . ALA A 1 114 ? 48.23100 32.39500 -1.86000  1.000 45.42000  ? 112 ALA A CB   1 
ATOM   1708 H H    . ALA A 1 114 ? 49.11400 32.01600 -4.18100  1.000 53.75000  ? 112 ALA A H    1 
ATOM   1709 H HA   . ALA A 1 114 ? 50.24600 32.03800 -1.73500  1.000 53.47000  ? 112 ALA A HA   1 
ATOM   1710 H HB1  . ALA A 1 114 ? 48.03600 32.16500 -0.93800  1.000 54.36000  ? 112 ALA A HB1  1 
ATOM   1711 H HB2  . ALA A 1 114 ? 48.34800 33.35400 -1.94500  1.000 54.36000  ? 112 ALA A HB2  1 
ATOM   1712 H HB3  . ALA A 1 114 ? 47.51000 32.09600 -2.43400  1.000 54.36000  ? 112 ALA A HB3  1 
ATOM   1713 N N    . THR A 1 115 ? 49.70600 29.79600 -0.80800  1.000 47.89000  ? 113 THR A N    1 
ATOM   1714 C CA   . THR A 1 115 ? 49.56300 28.41000 -0.39100  1.000 41.27000  ? 113 THR A CA   1 
ATOM   1715 C C    . THR A 1 115 ? 48.16700 28.20000 0.18100   1.000 52.35000  ? 113 THR A C    1 
ATOM   1716 O O    . THR A 1 115 ? 47.70100 28.99400 1.00800   1.000 43.51000  ? 113 THR A O    1 
ATOM   1717 C CB   . THR A 1 115 ? 50.62200 28.04500 0.64500   1.000 51.12000  ? 113 THR A CB   1 
ATOM   1718 O OG1  . THR A 1 115 ? 51.92100 28.15300 0.05200   1.000 55.79000  ? 113 THR A OG1  1 
ATOM   1719 C CG2  . THR A 1 115 ? 50.40100 26.63100 1.14200   1.000 51.34000  ? 113 THR A CG2  1 
ATOM   1720 H H    . THR A 1 115 ? 49.99800 30.31700 -0.18900  1.000 57.32000  ? 113 THR A H    1 
ATOM   1721 H HA   . THR A 1 115 ? 49.67100 27.82800 -1.15900  1.000 49.38000  ? 113 THR A HA   1 
ATOM   1722 H HB   . THR A 1 115 ? 50.55900 28.65100 1.40000   1.000 61.19000  ? 113 THR A HB   1 
ATOM   1723 H HG1  . THR A 1 115 ? 52.51100 27.95400 0.61500   1.000 66.80000  ? 113 THR A HG1  1 
ATOM   1724 H HG21 . THR A 1 115 ? 51.20700 26.30100 1.57000   1.000 61.46000  ? 113 THR A HG21 1 
ATOM   1725 H HG22 . THR A 1 115 ? 49.67300 26.61200 1.78400   1.000 61.46000  ? 113 THR A HG22 1 
ATOM   1726 H HG23 . THR A 1 115 ? 50.18100 26.05100 0.39600   1.000 61.46000  ? 113 THR A HG23 1 
ATOM   1727 N N    . VAL A 1 116 ? 47.49800 27.14600 -0.27000  1.000 41.61000  ? 114 VAL A N    1 
ATOM   1728 C CA   . VAL A 1 116 ? 46.16000 26.81100 0.19900   1.000 40.67000  ? 114 VAL A CA   1 
ATOM   1729 C C    . VAL A 1 116 ? 46.08900 25.30500 0.38200   1.000 36.90000  ? 114 VAL A C    1 
ATOM   1730 O O    . VAL A 1 116 ? 46.57000 24.53700 -0.45600  1.000 40.29000  ? 114 VAL A O    1 
ATOM   1731 C CB   . VAL A 1 116 ? 45.06700 27.30700 -0.77800  1.000 47.86000  ? 114 VAL A CB   1 
ATOM   1732 C CG1  . VAL A 1 116 ? 45.37100 26.87700 -2.19800  1.000 52.38000  ? 114 VAL A CG1  1 
ATOM   1733 C CG2  . VAL A 1 116 ? 43.70000 26.77800 -0.35200  1.000 50.58000  ? 114 VAL A CG2  1 
ATOM   1734 H H    . VAL A 1 116 ? 47.80400 26.59900 -0.85900  1.000 49.78000  ? 114 VAL A H    1 
ATOM   1735 H HA   . VAL A 1 116 ? 46.00800 27.22700 1.06100   1.000 48.66000  ? 114 VAL A HA   1 
ATOM   1736 H HB   . VAL A 1 116 ? 45.03700 28.27600 -0.75500  1.000 57.29000  ? 114 VAL A HB   1 
ATOM   1737 H HG11 . VAL A 1 116 ? 44.61400 27.10700 -2.75800  1.000 62.71000  ? 114 VAL A HG11 1 
ATOM   1738 H HG12 . VAL A 1 116 ? 46.16500 27.33800 -2.50700  1.000 62.71000  ? 114 VAL A HG12 1 
ATOM   1739 H HG13 . VAL A 1 116 ? 45.51500 25.91700 -2.21700  1.000 62.71000  ? 114 VAL A HG13 1 
ATOM   1740 H HG21 . VAL A 1 116 ? 43.01100 27.28500 -0.81000  1.000 60.54000  ? 114 VAL A HG21 1 
ATOM   1741 H HG22 . VAL A 1 116 ? 43.63200 25.84000 -0.59200  1.000 60.54000  ? 114 VAL A HG22 1 
ATOM   1742 H HG23 . VAL A 1 116 ? 43.60500 26.88600 0.60700   1.000 60.54000  ? 114 VAL A HG23 1 
ATOM   1743 N N    . GLY A 1 117 ? 45.49600 24.88100 1.49400   1.000 42.77000  ? 115 GLY A N    1 
ATOM   1744 C CA   . GLY A 1 117 ? 45.26900 23.47400 1.75500   1.000 36.43000  ? 115 GLY A CA   1 
ATOM   1745 C C    . GLY A 1 117 ? 43.84800 23.10400 1.36900   1.000 34.64000  ? 115 GLY A C    1 
ATOM   1746 O O    . GLY A 1 117 ? 42.89400 23.80700 1.71400   1.000 40.52000  ? 115 GLY A O    1 
ATOM   1747 H H    . GLY A 1 117 ? 45.21400 25.40100 2.11900   1.000 51.18000  ? 115 GLY A H    1 
ATOM   1748 H HA2  . GLY A 1 117 ? 45.88800 22.93400 1.24000   1.000 43.57000  ? 115 GLY A HA2  1 
ATOM   1749 H HA3  . GLY A 1 117 ? 45.39800 23.28800 2.69800   1.000 43.57000  ? 115 GLY A HA3  1 
ATOM   1750 N N    . GLY A 1 118 ? 43.71900 21.99700 0.65000   1.000 33.08000  ? 116 GLY A N    1 
ATOM   1751 C CA   . GLY A 1 118 ? 42.40300 21.52900 0.29000   1.000 34.14000  ? 116 GLY A CA   1 
ATOM   1752 C C    . GLY A 1 118 ? 42.42300 20.27400 -0.54800  1.000 39.37000  ? 116 GLY A C    1 
ATOM   1753 O O    . GLY A 1 118 ? 43.33900 19.44800 -0.44200  1.000 34.57000  ? 116 GLY A O    1 
ATOM   1754 H H    . GLY A 1 118 ? 44.36900 21.51000 0.36600   1.000 39.55000  ? 116 GLY A H    1 
ATOM   1755 H HA2  . GLY A 1 118 ? 41.89500 21.34900 1.09600   1.000 40.82000  ? 116 GLY A HA2  1 
ATOM   1756 H HA3  . GLY A 1 118 ? 41.94500 22.22100 -0.21100  1.000 40.82000  ? 116 GLY A HA3  1 
ATOM   1757 N N    . GLN A 1 119 ? 41.41000 20.12700 -1.38900  1.000 30.45000  ? 117 GLN A N    1 
ATOM   1758 C CA   . GLN A 1 119 ? 41.26000 18.94600 -2.22100  1.000 32.14000  ? 117 GLN A CA   1 
ATOM   1759 C C    . GLN A 1 119 ? 40.84000 19.38000 -3.61400  1.000 38.75000  ? 117 GLN A C    1 
ATOM   1760 O O    . GLN A 1 119 ? 39.97600 20.25000 -3.76800  1.000 33.13000  ? 117 GLN A O    1 
ATOM   1761 C CB   . GLN A 1 119 ? 40.22500 17.98400 -1.64900  1.000 37.86000  ? 117 GLN A CB   1 
ATOM   1762 C CG   . GLN A 1 119 ? 40.17300 16.66600 -2.38100  1.000 36.70000  ? 117 GLN A CG   1 
ATOM   1763 C CD   . GLN A 1 119 ? 39.26800 15.67400 -1.70800  1.000 41.09000  ? 117 GLN A CD   1 
ATOM   1764 O OE1  . GLN A 1 119 ? 38.43500 16.03800 -0.87700  1.000 38.08000  ? 117 GLN A OE1  1 
ATOM   1765 N NE2  . GLN A 1 119 ? 39.42000 14.40600 -2.06800  1.000 34.43000  ? 117 GLN A NE2  1 
ATOM   1766 H H    . GLN A 1 119 ? 40.78500 20.70800 -1.49700  1.000 36.40000  ? 117 GLN A H    1 
ATOM   1767 H HA   . GLN A 1 119 ? 42.10900 18.48200 -2.28700  1.000 38.42000  ? 117 GLN A HA   1 
ATOM   1768 H HB2  . GLN A 1 119 ? 40.44300 17.80200 -0.72200  1.000 45.28000  ? 117 GLN A HB2  1 
ATOM   1769 H HB3  . GLN A 1 119 ? 39.34900 18.39400 -1.70900  1.000 45.28000  ? 117 GLN A HB3  1 
ATOM   1770 H HG2  . GLN A 1 119 ? 39.84000 16.81500 -3.28000  1.000 43.90000  ? 117 GLN A HG2  1 
ATOM   1771 H HG3  . GLN A 1 119 ? 41.06400 16.28600 -2.41500  1.000 43.90000  ? 117 GLN A HG3  1 
ATOM   1772 H HE21 . GLN A 1 119 ? 40.01300 14.19300 -2.65400  1.000 41.16000  ? 117 GLN A HE21 1 
ATOM   1773 H HE22 . GLN A 1 119 ? 38.92700 13.79700 -1.71400  1.000 41.16000  ? 117 GLN A HE22 1 
ATOM   1774 N N    . MET A 1 120 ? 41.46500 18.77400 -4.62100  1.000 34.07000  ? 118 MET A N    1 
ATOM   1775 C CA   . MET A 1 120 ? 41.09100 19.01100 -6.00000  1.000 31.37000  ? 118 MET A CA   1 
ATOM   1776 C C    . MET A 1 120 ? 39.84200 18.22200 -6.35000  1.000 34.15000  ? 118 MET A C    1 
ATOM   1777 O O    . MET A 1 120 ? 39.59600 17.13800 -5.81900  1.000 35.25000  ? 118 MET A O    1 
ATOM   1778 C CB   . MET A 1 120 ? 42.21300 18.59100 -6.94800  1.000 41.73000  ? 118 MET A CB   1 
ATOM   1779 C CG   . MET A 1 120 ? 43.37000 19.54800 -7.01100  1.000 48.10000  ? 118 MET A CG   1 
ATOM   1780 S SD   . MET A 1 120 ? 44.83000 18.77300 -7.72800  1.000 54.21000  ? 118 MET A SD   1 
ATOM   1781 C CE   . MET A 1 120 ? 46.07100 19.97200 -7.24400  1.000 63.16000  ? 118 MET A CE   1 
ATOM   1782 H H    . MET A 1 120 ? 42.11300 18.21700 -4.52500  1.000 40.74000  ? 118 MET A H    1 
ATOM   1783 H HA   . MET A 1 120 ? 40.92000 19.95700 -6.12800  1.000 37.50000  ? 118 MET A HA   1 
ATOM   1784 H HB2  . MET A 1 120 ? 42.55800 17.73200 -6.66000  1.000 49.93000  ? 118 MET A HB2  1 
ATOM   1785 H HB3  . MET A 1 120 ? 41.84900 18.51300 -7.84400  1.000 49.93000  ? 118 MET A HB3  1 
ATOM   1786 H HG2  . MET A 1 120 ? 43.12700 20.30900 -7.56300  1.000 57.57000  ? 118 MET A HG2  1 
ATOM   1787 H HG3  . MET A 1 120 ? 43.59100 19.84100 -6.11300  1.000 57.57000  ? 118 MET A HG3  1 
ATOM   1788 H HE1  . MET A 1 120 ? 46.59500 20.21800 -8.02000  1.000 75.65000  ? 118 MET A HE1  1 
ATOM   1789 H HE2  . MET A 1 120 ? 45.61200 20.75800 -6.92200  1.000 75.65000  ? 118 MET A HE2  1 
ATOM   1790 H HE3  . MET A 1 120 ? 46.62400 19.60300 -6.53900  1.000 75.65000  ? 118 MET A HE3  1 
ATOM   1791 N N    . GLY A 1 121 ? 39.06500 18.76800 -7.28100  1.000 36.65000  ? 119 GLY A N    1 
ATOM   1792 C CA   . GLY A 1 121 ? 37.90600 18.07600 -7.79700  1.000 35.89000  ? 119 GLY A CA   1 
ATOM   1793 C C    . GLY A 1 121 ? 37.75000 18.34100 -9.27900  1.000 37.15000  ? 119 GLY A C    1 
ATOM   1794 O O    . GLY A 1 121 ? 38.38300 19.23800 -9.84400  1.000 39.91000  ? 119 GLY A O    1 
ATOM   1795 H H    . GLY A 1 121 ? 39.19400 19.54400 -7.62700  1.000 43.83000  ? 119 GLY A H    1 
ATOM   1796 H HA2  . GLY A 1 121 ? 38.00200 17.12100 -7.65800  1.000 42.92000  ? 119 GLY A HA2  1 
ATOM   1797 H HA3  . GLY A 1 121 ? 37.10800 18.38100 -7.33800  1.000 42.92000  ? 119 GLY A HA3  1 
ATOM   1798 N N    . MET A 1 122 ? 36.88700 17.53800 -9.89800  1.000 42.18000  ? 120 MET A N    1 
ATOM   1799 C CA   . MET A 1 122 ? 36.61700 17.59700 -11.32700 1.000 40.62000  ? 120 MET A CA   1 
ATOM   1800 C C    . MET A 1 122 ? 35.11600 17.72000 -11.52000 1.000 39.36000  ? 120 MET A C    1 
ATOM   1801 O O    . MET A 1 122 ? 34.37100 16.81800 -11.13300 1.000 38.42000  ? 120 MET A O    1 
ATOM   1802 C CB   . MET A 1 122 ? 37.13900 16.33800 -12.02800 1.000 43.76000  ? 120 MET A CB   1 
ATOM   1803 C CG   . MET A 1 122 ? 37.27500 16.46500 -13.53100 1.000 56.55000  ? 120 MET A CG   1 
ATOM   1804 S SD   . MET A 1 122 ? 38.96600 16.86800 -14.01200 1.000 78.46000  ? 120 MET A SD   1 
ATOM   1805 C CE   . MET A 1 122 ? 38.87500 18.65500 -14.07800 1.000 60.89000  ? 120 MET A CE   1 
ATOM   1806 H H    . MET A 1 122 ? 36.43200 16.93100 -9.49300  1.000 50.47000  ? 120 MET A H    1 
ATOM   1807 H HA   . MET A 1 122 ? 37.05700 18.37000 -11.71100 1.000 48.59000  ? 120 MET A HA   1 
ATOM   1808 H HB2  . MET A 1 122 ? 38.01500 16.12500 -11.67100 1.000 52.36000  ? 120 MET A HB2  1 
ATOM   1809 H HB3  . MET A 1 122 ? 36.52700 15.60700 -11.84900 1.000 52.36000  ? 120 MET A HB3  1 
ATOM   1810 H HG2  . MET A 1 122 ? 37.03400 15.62200 -13.94600 1.000 67.71000  ? 120 MET A HG2  1 
ATOM   1811 H HG3  . MET A 1 122 ? 36.69300 17.17300 -13.84600 1.000 67.71000  ? 120 MET A HG3  1 
ATOM   1812 H HE1  . MET A 1 122 ? 39.73200 19.00300 -14.36800 1.000 72.92000  ? 120 MET A HE1  1 
ATOM   1813 H HE2  . MET A 1 122 ? 38.18700 18.91000 -14.70800 1.000 72.92000  ? 120 MET A HE2  1 
ATOM   1814 H HE3  . MET A 1 122 ? 38.66000 18.99000 -13.19500 1.000 72.92000  ? 120 MET A HE3  1 
ATOM   1815 N N    . LEU A 1 123 ? 34.67200 18.82700 -12.10800 1.000 43.23000  ? 121 LEU A N    1 
ATOM   1816 C CA   . LEU A 1 123 ? 33.26100 18.96500 -12.45800 1.000 45.16000  ? 121 LEU A CA   1 
ATOM   1817 C C    . LEU A 1 123 ? 32.91700 17.93900 -13.53400 1.000 50.37000  ? 121 LEU A C    1 
ATOM   1818 O O    . LEU A 1 123 ? 33.61900 17.82800 -14.54500 1.000 46.53000  ? 121 LEU A O    1 
ATOM   1819 C CB   . LEU A 1 123 ? 32.95400 20.37600 -12.93400 1.000 40.04000  ? 121 LEU A CB   1 
ATOM   1820 C CG   . LEU A 1 123 ? 33.23600 21.49600 -11.93500 1.000 42.37000  ? 121 LEU A CG   1 
ATOM   1821 C CD1  . LEU A 1 123 ? 32.79000 22.83600 -12.50500 1.000 48.99000  ? 121 LEU A CD1  1 
ATOM   1822 C CD2  . LEU A 1 123 ? 32.55900 21.25400 -10.60000 1.000 36.73000  ? 121 LEU A CD2  1 
ATOM   1823 H H    . LEU A 1 123 ? 35.16000 19.50500 -12.31300 1.000 51.73000  ? 121 LEU A H    1 
ATOM   1824 H HA   . LEU A 1 123 ? 32.71700 18.77700 -11.67700 1.000 54.04000  ? 121 LEU A HA   1 
ATOM   1825 H HB2  . LEU A 1 123 ? 33.48100 20.55500 -13.72700 1.000 47.90000  ? 121 LEU A HB2  1 
ATOM   1826 H HB3  . LEU A 1 123 ? 32.01100 20.42100 -13.15800 1.000 47.90000  ? 121 LEU A HB3  1 
ATOM   1827 H HG   . LEU A 1 123 ? 34.19200 21.54300 -11.77800 1.000 50.69000  ? 121 LEU A HG   1 
ATOM   1828 H HD11 . LEU A 1 123 ? 32.98300 23.53300 -11.86000 1.000 58.64000  ? 121 LEU A HD11 1 
ATOM   1829 H HD12 . LEU A 1 123 ? 33.27300 23.00400 -13.32900 1.000 58.64000  ? 121 LEU A HD12 1 
ATOM   1830 H HD13 . LEU A 1 123 ? 31.83700 22.80200 -12.68200 1.000 58.64000  ? 121 LEU A HD13 1 
ATOM   1831 H HD21 . LEU A 1 123 ? 32.65500 22.04700 -10.05000 1.000 43.93000  ? 121 LEU A HD21 1 
ATOM   1832 H HD22 . LEU A 1 123 ? 31.61900 21.06900 -10.75200 1.000 43.93000  ? 121 LEU A HD22 1 
ATOM   1833 H HD23 . LEU A 1 123 ? 32.98000 20.49600 -10.16500 1.000 43.93000  ? 121 LEU A HD23 1 
ATOM   1834 N N    . LEU A 1 124 ? 31.82700 17.19800 -13.32600 1.000 50.19000  ? 122 LEU A N    1 
ATOM   1835 C CA   . LEU A 1 124 ? 31.60800 15.96700 -14.08100 1.000 56.65000  ? 122 LEU A CA   1 
ATOM   1836 C C    . LEU A 1 124 ? 31.14400 16.24000 -15.51000 1.000 74.43000  ? 122 LEU A C    1 
ATOM   1837 O O    . LEU A 1 124 ? 31.75100 15.75700 -16.47500 1.000 81.66000  ? 122 LEU A O    1 
ATOM   1838 C CB   . LEU A 1 124 ? 30.59500 15.08100 -13.35500 1.000 54.23000  ? 122 LEU A CB   1 
ATOM   1839 C CG   . LEU A 1 124 ? 31.14200 14.25200 -12.19000 1.000 48.72000  ? 122 LEU A CG   1 
ATOM   1840 C CD1  . LEU A 1 124 ? 30.09000 13.23700 -11.74200 1.000 56.14000  ? 122 LEU A CD1  1 
ATOM   1841 C CD2  . LEU A 1 124 ? 32.44400 13.53800 -12.52500 1.000 59.42000  ? 122 LEU A CD2  1 
ATOM   1842 H H    . LEU A 1 124 ? 31.20800 17.38400 -12.75900 1.000 60.09000  ? 122 LEU A H    1 
ATOM   1843 H HA   . LEU A 1 124 ? 32.45000 15.49300 -14.14600 1.000 67.83000  ? 122 LEU A HA   1 
ATOM   1844 H HB2  . LEU A 1 124 ? 29.89200 15.64800 -13.00100 1.000 64.93000  ? 122 LEU A HB2  1 
ATOM   1845 H HB3  . LEU A 1 124 ? 30.21600 14.46100 -13.99800 1.000 64.93000  ? 122 LEU A HB3  1 
ATOM   1846 H HG   . LEU A 1 124 ? 31.31500 14.84400 -11.44200 1.000 58.31000  ? 122 LEU A HG   1 
ATOM   1847 H HD11 . LEU A 1 124 ? 30.42900 12.74800 -10.97600 1.000 67.22000  ? 122 LEU A HD11 1 
ATOM   1848 H HD12 . LEU A 1 124 ? 29.27800 13.71000 -11.50200 1.000 67.22000  ? 122 LEU A HD12 1 
ATOM   1849 H HD13 . LEU A 1 124 ? 29.91300 12.62400 -12.47400 1.000 67.22000  ? 122 LEU A HD13 1 
ATOM   1850 H HD21 . LEU A 1 124 ? 32.59200 12.83200 -11.87600 1.000 71.16000  ? 122 LEU A HD21 1 
ATOM   1851 H HD22 . LEU A 1 124 ? 32.37500 13.15900 -13.41500 1.000 71.16000  ? 122 LEU A HD22 1 
ATOM   1852 H HD23 . LEU A 1 124 ? 33.17300 14.17700 -12.49200 1.000 71.16000  ? 122 LEU A HD23 1 
ATOM   1853 N N    . THR A 1 125 ? 30.06000 16.98700 -15.67000 1.000 63.12000  ? 123 THR A N    1 
ATOM   1854 C CA   . THR A 1 125 ? 29.53900 17.23100 -17.01000 1.000 78.87000  ? 123 THR A CA   1 
ATOM   1855 C C    . THR A 1 125 ? 30.35800 18.31800 -17.70700 1.000 80.90000  ? 123 THR A C    1 
ATOM   1856 O O    . THR A 1 125 ? 31.48600 18.07700 -18.14300 1.000 71.39000  ? 123 THR A O    1 
ATOM   1857 C CB   . THR A 1 125 ? 28.05800 17.63400 -16.97900 1.000 88.55000  ? 123 THR A CB   1 
ATOM   1858 O OG1  . THR A 1 125 ? 27.48300 17.42100 -18.27400 1.000 96.15000  ? 123 THR A OG1  1 
ATOM   1859 C CG2  . THR A 1 125 ? 27.90300 19.09400 -16.57600 1.000 92.65000  ? 123 THR A CG2  1 
ATOM   1860 H H    . THR A 1 125 ? 29.61500 17.35800 -15.03500 1.000 75.59000  ? 123 THR A H    1 
ATOM   1861 H HA   . THR A 1 125 ? 29.61600 16.41700 -17.53300 1.000 94.49000  ? 123 THR A HA   1 
ATOM   1862 H HB   . THR A 1 125 ? 27.59100 17.08800 -16.32700 1.000 106.12000 ? 123 THR A HB   1 
ATOM   1863 H HG1  . THR A 1 125 ? 26.67200 17.63900 -18.26700 1.000 115.23000 ? 123 THR A HG1  1 
ATOM   1864 H HG21 . THR A 1 125 ? 27.00100 19.25500 -16.25900 1.000 111.03000 ? 123 THR A HG21 1 
ATOM   1865 H HG22 . THR A 1 125 ? 28.52900 19.31000 -15.86800 1.000 111.03000 ? 123 THR A HG22 1 
ATOM   1866 H HG23 . THR A 1 125 ? 28.07500 19.67100 -17.33700 1.000 111.03000 ? 123 THR A HG23 1 
ATOM   1867 N N    . GLY A 1 135 ? 29.97400 26.46700 -15.43900 1.000 55.93000  ? 133 GLY A N    1 
ATOM   1868 C CA   . GLY A 1 135 ? 30.62900 25.87600 -14.28800 1.000 54.83000  ? 133 GLY A CA   1 
ATOM   1869 C C    . GLY A 1 135 ? 30.54200 26.71900 -13.02600 1.000 58.04000  ? 133 GLY A C    1 
ATOM   1870 O O    . GLY A 1 135 ? 29.46100 26.91100 -12.47400 1.000 59.41000  ? 133 GLY A O    1 
ATOM   1871 H HA2  . GLY A 1 135 ? 30.22800 25.01200 -14.10300 1.000 65.65000  ? 133 GLY A HA2  1 
ATOM   1872 H HA3  . GLY A 1 135 ? 31.56700 25.73700 -14.49400 1.000 65.65000  ? 133 GLY A HA3  1 
ATOM   1873 N N    . THR A 1 136 ? 31.68700 27.21300 -12.56000 1.000 47.82000  ? 134 THR A N    1 
ATOM   1874 C CA   . THR A 1 136 ? 31.76300 28.07700 -11.39400 1.000 39.08000  ? 134 THR A CA   1 
ATOM   1875 C C    . THR A 1 136 ? 32.23300 29.46600 -11.81100 1.000 51.21000  ? 134 THR A C    1 
ATOM   1876 O O    . THR A 1 136 ? 32.85100 29.65000 -12.86100 1.000 47.74000  ? 134 THR A O    1 
ATOM   1877 C CB   . THR A 1 136 ? 32.70600 27.49300 -10.33800 1.000 49.33000  ? 134 THR A CB   1 
ATOM   1878 O OG1  . THR A 1 136 ? 33.93400 27.08900 -10.95300 1.000 47.46000  ? 134 THR A OG1  1 
ATOM   1879 C CG2  . THR A 1 136 ? 32.06100 26.28600 -9.65400  1.000 44.62000  ? 134 THR A CG2  1 
ATOM   1880 H H    . THR A 1 136 ? 32.45300 27.05400 -12.91700 1.000 57.24000  ? 134 THR A H    1 
ATOM   1881 H HA   . THR A 1 136 ? 30.88200 28.16200 -10.99700 1.000 46.75000  ? 134 THR A HA   1 
ATOM   1882 H HB   . THR A 1 136 ? 32.88900 28.16500 -9.66300  1.000 59.04000  ? 134 THR A HB   1 
ATOM   1883 H HG1  . THR A 1 136 ? 34.44600 26.75400 -10.37800 1.000 56.80000  ? 134 THR A HG1  1 
ATOM   1884 H HG21 . THR A 1 136 ? 32.66400 25.92100 -8.98600  1.000 53.40000  ? 134 THR A HG21 1 
ATOM   1885 H HG22 . THR A 1 136 ? 31.23600 26.55300 -9.22000  1.000 53.40000  ? 134 THR A HG22 1 
ATOM   1886 H HG23 . THR A 1 136 ? 31.86600 25.59900 -10.31000 1.000 53.40000  ? 134 THR A HG23 1 
ATOM   1887 N N    . THR A 1 137 ? 31.92400 30.45300 -10.96300 1.000 46.28000  ? 135 THR A N    1 
ATOM   1888 C CA   . THR A 1 137 ? 32.17600 31.85600 -11.26700 1.000 38.50000  ? 135 THR A CA   1 
ATOM   1889 C C    . THR A 1 137 ? 32.71100 32.60000 -10.05000 1.000 37.91000  ? 135 THR A C    1 
ATOM   1890 O O    . THR A 1 137 ? 32.68400 32.06800 -8.93600  1.000 45.55000  ? 135 THR A O    1 
ATOM   1891 C CB   . THR A 1 137 ? 30.88700 32.53600 -11.75800 1.000 48.01000  ? 135 THR A CB   1 
ATOM   1892 O OG1  . THR A 1 137 ? 29.86300 32.40800 -10.75600 1.000 50.84000  ? 135 THR A OG1  1 
ATOM   1893 C CG2  . THR A 1 137 ? 30.40000 31.90500 -13.05200 1.000 50.47000  ? 135 THR A CG2  1 
ATOM   1894 H H    . THR A 1 137 ? 31.56000 30.32800 -10.19300 1.000 55.39000  ? 135 THR A H    1 
ATOM   1895 H HA   . THR A 1 137 ? 32.83600 31.91000 -11.97500 1.000 46.06000  ? 135 THR A HA   1 
ATOM   1896 H HB   . THR A 1 137 ? 31.05000 33.47500 -11.92500 1.000 57.47000  ? 135 THR A HB   1 
ATOM   1897 H HG1  . THR A 1 137 ? 29.15600 32.77900 -11.02000 1.000 60.86000  ? 135 THR A HG1  1 
ATOM   1898 H HG21 . THR A 1 137 ? 29.62600 32.38500 -13.38300 1.000 60.42000  ? 135 THR A HG21 1 
ATOM   1899 H HG22 . THR A 1 137 ? 31.10200 31.93800 -13.72100 1.000 60.42000  ? 135 THR A HG22 1 
ATOM   1900 H HG23 . THR A 1 137 ? 30.15500 30.97900 -12.89900 1.000 60.42000  ? 135 THR A HG23 1 
ATOM   1901 N N    . PRO A 1 138 ? 33.18400 33.83400 -10.22600 1.000 43.63000  ? 136 PRO A N    1 
ATOM   1902 C CA   . PRO A 1 138 ? 33.76200 34.57000 -9.08600  1.000 46.33000  ? 136 PRO A CA   1 
ATOM   1903 C C    . PRO A 1 138 ? 32.83300 34.76700 -7.89600  1.000 52.85000  ? 136 PRO A C    1 
ATOM   1904 O O    . PRO A 1 138 ? 33.31900 34.95000 -6.76900  1.000 57.64000  ? 136 PRO A O    1 
ATOM   1905 C CB   . PRO A 1 138 ? 34.15000 35.92200 -9.71500  1.000 39.91000  ? 136 PRO A CB   1 
ATOM   1906 C CG   . PRO A 1 138 ? 34.44800 35.57800 -11.13900 1.000 46.84000  ? 136 PRO A CG   1 
ATOM   1907 C CD   . PRO A 1 138 ? 33.48300 34.47600 -11.51800 1.000 41.46000  ? 136 PRO A CD   1 
ATOM   1908 H HA   . PRO A 1 138 ? 34.56600 34.12800 -8.77600  1.000 55.44000  ? 136 PRO A HA   1 
ATOM   1909 H HB2  . PRO A 1 138 ? 33.40500 36.54000 -9.65600  1.000 47.74000  ? 136 PRO A HB2  1 
ATOM   1910 H HB3  . PRO A 1 138 ? 34.93600 36.27900 -9.27200  1.000 47.74000  ? 136 PRO A HB3  1 
ATOM   1911 H HG2  . PRO A 1 138 ? 34.30900 36.35900 -11.69700 1.000 56.06000  ? 136 PRO A HG2  1 
ATOM   1912 H HG3  . PRO A 1 138 ? 35.36400 35.26800 -11.21200 1.000 56.06000  ? 136 PRO A HG3  1 
ATOM   1913 H HD2  . PRO A 1 138 ? 32.68100 34.85800 -11.90700 1.000 49.61000  ? 136 PRO A HD2  1 
ATOM   1914 H HD3  . PRO A 1 138 ? 33.91000 33.84900 -12.12300 1.000 49.61000  ? 136 PRO A HD3  1 
ATOM   1915 N N    . GLY A 1 139 ? 31.52500 34.75600 -8.09500  1.000 44.69000  ? 137 GLY A N    1 
ATOM   1916 C CA   . GLY A 1 139 ? 30.63500 34.93200 -6.96800  1.000 42.44000  ? 137 GLY A CA   1 
ATOM   1917 C C    . GLY A 1 139 ? 30.35600 33.68700 -6.16400  1.000 40.90000  ? 137 GLY A C    1 
ATOM   1918 O O    . GLY A 1 139 ? 29.60800 33.74800 -5.18300  1.000 37.06000  ? 137 GLY A O    1 
ATOM   1919 H H    . GLY A 1 139 ? 31.13700 34.65200 -8.85500  1.000 53.48000  ? 137 GLY A H    1 
ATOM   1920 H HA2  . GLY A 1 139 ? 31.01100 35.59600 -6.36900  1.000 50.78000  ? 137 GLY A HA2  1 
ATOM   1921 H HA3  . GLY A 1 139 ? 29.78600 35.27100 -7.29300  1.000 50.78000  ? 137 GLY A HA3  1 
ATOM   1922 N N    . ASP A 1 140 ? 30.94300 32.55900 -6.54200  1.000 34.29000  ? 138 ASP A N    1 
ATOM   1923 C CA   . ASP A 1 140 ? 30.60500 31.27000 -5.95900  1.000 39.23000  ? 138 ASP A CA   1 
ATOM   1924 C C    . ASP A 1 140 ? 31.50700 30.86400 -4.79700  1.000 37.00000  ? 138 ASP A C    1 
ATOM   1925 O O    . ASP A 1 140 ? 31.27700 29.80900 -4.19300  1.000 36.62000  ? 138 ASP A O    1 
ATOM   1926 C CB   . ASP A 1 140 ? 30.66700 30.16800 -7.02600  1.000 33.88000  ? 138 ASP A CB   1 
ATOM   1927 C CG   . ASP A 1 140 ? 29.64400 30.34700 -8.12600  1.000 43.54000  ? 138 ASP A CG   1 
ATOM   1928 O OD1  . ASP A 1 140 ? 28.69000 31.13100 -7.94600  1.000 40.37000  ? 138 ASP A OD1  1 
ATOM   1929 O OD2  . ASP A 1 140 ? 29.79800 29.68900 -9.17500  1.000 38.78000  ? 138 ASP A OD2  1 
ATOM   1930 H H    . ASP A 1 140 ? 31.55300 32.51400 -7.14700  1.000 41.00000  ? 138 ASP A H    1 
ATOM   1931 H HA   . ASP A 1 140 ? 29.69500 31.30800 -5.62700  1.000 46.93000  ? 138 ASP A HA   1 
ATOM   1932 H HB2  . ASP A 1 140 ? 31.54600 30.17800 -7.43500  1.000 40.51000  ? 138 ASP A HB2  1 
ATOM   1933 H HB3  . ASP A 1 140 ? 30.51300 29.31200 -6.60100  1.000 40.51000  ? 138 ASP A HB3  1 
ATOM   1934 N N    . CYS A 1 141 ? 32.53200 31.64000 -4.48100  1.000 36.52000  ? 139 CYS A N    1 
ATOM   1935 C CA   . CYS A 1 141 ? 33.42400 31.21800 -3.40900  1.000 34.80000  ? 139 CYS A CA   1 
ATOM   1936 C C    . CYS A 1 141 ? 32.65400 31.17400 -2.09100  1.000 36.22000  ? 139 CYS A C    1 
ATOM   1937 O O    . CYS A 1 141 ? 31.74900 31.97900 -1.85100  1.000 35.35000  ? 139 CYS A O    1 
ATOM   1938 C CB   . CYS A 1 141 ? 34.62400 32.14800 -3.30300  1.000 39.09000  ? 139 CYS A CB   1 
ATOM   1939 S SG   . CYS A 1 141 ? 35.92100 31.75100 -4.52000  1.000 35.06000  ? 139 CYS A SG   1 
ATOM   1940 H H    . CYS A 1 141 ? 32.73200 32.38900 -4.85300  1.000 43.68000  ? 139 CYS A H    1 
ATOM   1941 H HA   . CYS A 1 141 ? 33.75000 30.32400 -3.59900  1.000 41.61000  ? 139 CYS A HA   1 
ATOM   1942 H HB2  . CYS A 1 141 ? 34.33000 33.05900 -3.45700  1.000 46.76000  ? 139 CYS A HB2  1 
ATOM   1943 H HB3  . CYS A 1 141 ? 35.01000 32.06800 -2.41700  1.000 46.76000  ? 139 CYS A HB3  1 
ATOM   1944 N N    . GLY A 1 142 ? 33.01400 30.20900 -1.24500  1.000 35.08000  ? 140 GLY A N    1 
ATOM   1945 C CA   . GLY A 1 142 ? 32.36600 29.99100 0.01600   1.000 27.98000  ? 140 GLY A CA   1 
ATOM   1946 C C    . GLY A 1 142 ? 31.28900 28.92600 -0.00600  1.000 32.60000  ? 140 GLY A C    1 
ATOM   1947 O O    . GLY A 1 142 ? 30.89300 28.43800 1.05900   1.000 35.30000  ? 140 GLY A O    1 
ATOM   1948 H H    . GLY A 1 142 ? 33.65500 29.65600 -1.39800  1.000 41.95000  ? 140 GLY A H    1 
ATOM   1949 H HA2  . GLY A 1 142 ? 33.03100 29.73000 0.67200   1.000 33.42000  ? 140 GLY A HA2  1 
ATOM   1950 H HA3  . GLY A 1 142 ? 31.96200 30.82100 0.31000   1.000 33.42000  ? 140 GLY A HA3  1 
ATOM   1951 N N    . CYS A 1 143 ? 30.80000 28.55500 -1.17700  1.000 36.27000  ? 141 CYS A N    1 
ATOM   1952 C CA   . CYS A 1 143 ? 29.74900 27.55500 -1.22300  1.000 37.95000  ? 141 CYS A CA   1 
ATOM   1953 C C    . CYS A 1 143 ? 30.31400 26.20200 -0.80400  1.000 33.00000  ? 141 CYS A C    1 
ATOM   1954 O O    . CYS A 1 143 ? 31.50400 25.92700 -0.99800  1.000 40.51000  ? 141 CYS A O    1 
ATOM   1955 C CB   . CYS A 1 143 ? 29.15100 27.46500 -2.61500  1.000 47.69000  ? 141 CYS A CB   1 
ATOM   1956 S SG   . CYS A 1 143 ? 28.13600 28.88600 -3.03700  1.000 41.00000  ? 141 CYS A SG   1 
ATOM   1957 H H    . CYS A 1 143 ? 31.05000 28.85800 -1.94200  1.000 43.38000  ? 141 CYS A H    1 
ATOM   1958 H HA   . CYS A 1 143 ? 29.04900 27.81400 -0.60500  1.000 45.39000  ? 141 CYS A HA   1 
ATOM   1959 H HB2  . CYS A 1 143 ? 29.87000 27.40800 -3.26400  1.000 57.08000  ? 141 CYS A HB2  1 
ATOM   1960 H HB3  . CYS A 1 143 ? 28.59400 26.67200 -2.66900  1.000 57.08000  ? 141 CYS A HB3  1 
ATOM   1961 H HG   . CYS A 1 143 ? 28.85500 29.84500 -3.04800  1.000 49.05000  ? 141 CYS A HG   1 
ATOM   1962 N N    . PRO A 1 144 ? 29.48700 25.34100 -0.22700  1.000 32.40000  ? 142 PRO A N    1 
ATOM   1963 C CA   . PRO A 1 144 ? 30.00100 24.10800 0.36800   1.000 34.71000  ? 142 PRO A CA   1 
ATOM   1964 C C    . PRO A 1 144 ? 30.04900 22.93800 -0.59800  1.000 32.88000  ? 142 PRO A C    1 
ATOM   1965 O O    . PRO A 1 144 ? 29.27400 22.83900 -1.55000  1.000 38.06000  ? 142 PRO A O    1 
ATOM   1966 C CB   . PRO A 1 144 ? 28.98400 23.83500 1.49100   1.000 35.73000  ? 142 PRO A CB   1 
ATOM   1967 C CG   . PRO A 1 144 ? 27.69200 24.33200 0.91300   1.000 31.85000  ? 142 PRO A CG   1 
ATOM   1968 C CD   . PRO A 1 144 ? 28.03800 25.50200 0.00600   1.000 35.71000  ? 142 PRO A CD   1 
ATOM   1969 H HA   . PRO A 1 144 ? 30.88000 24.25300 0.75200   1.000 41.50000  ? 142 PRO A HA   1 
ATOM   1970 H HB2  . PRO A 1 144 ? 28.94000 22.88400 1.67400   1.000 42.73000  ? 142 PRO A HB2  1 
ATOM   1971 H HB3  . PRO A 1 144 ? 29.22600 24.33400 2.28600   1.000 42.73000  ? 142 PRO A HB3  1 
ATOM   1972 H HG2  . PRO A 1 144 ? 27.27400 23.62100 0.40300   1.000 38.07000  ? 142 PRO A HG2  1 
ATOM   1973 H HG3  . PRO A 1 144 ? 27.10900 24.62300 1.63000   1.000 38.07000  ? 142 PRO A HG3  1 
ATOM   1974 H HD2  . PRO A 1 144 ? 27.55100 25.43800 -0.83000  1.000 42.70000  ? 142 PRO A HD2  1 
ATOM   1975 H HD3  . PRO A 1 144 ? 27.85500 26.33900 0.46000   1.000 42.70000  ? 142 PRO A HD3  1 
ATOM   1976 N N    . TYR A 1 145 ? 30.99300 22.04100 -0.32200  1.000 32.26000  ? 143 TYR A N    1 
ATOM   1977 C CA   . TYR A 1 145 ? 31.04800 20.73000 -0.95500  1.000 33.64000  ? 143 TYR A CA   1 
ATOM   1978 C C    . TYR A 1 145 ? 30.48300 19.71400 0.03100   1.000 36.52000  ? 143 TYR A C    1 
ATOM   1979 O O    . TYR A 1 145 ? 30.89400 19.69000 1.19400   1.000 38.32000  ? 143 TYR A O    1 
ATOM   1980 C CB   . TYR A 1 145 ? 32.48200 20.33900 -1.32000  1.000 36.04000  ? 143 TYR A CB   1 
ATOM   1981 C CG   . TYR A 1 145 ? 33.08600 21.09700 -2.47900  1.000 32.63000  ? 143 TYR A CG   1 
ATOM   1982 C CD1  . TYR A 1 145 ? 33.51600 22.40600 -2.32600  1.000 36.18000  ? 143 TYR A CD1  1 
ATOM   1983 C CD2  . TYR A 1 145 ? 33.24400 20.49700 -3.72100  1.000 32.72000  ? 143 TYR A CD2  1 
ATOM   1984 C CE1  . TYR A 1 145 ? 34.07900 23.10400 -3.38500  1.000 33.15000  ? 143 TYR A CE1  1 
ATOM   1985 C CE2  . TYR A 1 145 ? 33.80300 21.18900 -4.78800  1.000 38.31000  ? 143 TYR A CE2  1 
ATOM   1986 C CZ   . TYR A 1 145 ? 34.21900 22.49100 -4.60800  1.000 30.63000  ? 143 TYR A CZ   1 
ATOM   1987 O OH   . TYR A 1 145 ? 34.78200 23.19100 -5.66300  1.000 37.33000  ? 143 TYR A OH   1 
ATOM   1988 H H    . TYR A 1 145 ? 31.62700 22.17500 0.24300   1.000 38.56000  ? 143 TYR A H    1 
ATOM   1989 H HA   . TYR A 1 145 ? 30.50600 20.72500 -1.75900  1.000 40.23000  ? 143 TYR A HA   1 
ATOM   1990 H HB2  . TYR A 1 145 ? 33.04700 20.49000 -0.54700  1.000 43.10000  ? 143 TYR A HB2  1 
ATOM   1991 H HB3  . TYR A 1 145 ? 32.49400 19.39700 -1.55200  1.000 43.10000  ? 143 TYR A HB3  1 
ATOM   1992 H HD1  . TYR A 1 145 ? 33.42300 22.82500 -1.50100  1.000 43.27000  ? 143 TYR A HD1  1 
ATOM   1993 H HD2  . TYR A 1 145 ? 32.96200 19.61900 -3.84300  1.000 39.12000  ? 143 TYR A HD2  1 
ATOM   1994 H HE1  . TYR A 1 145 ? 34.35900 23.98200 -3.26900  1.000 39.64000  ? 143 TYR A HE1  1 
ATOM   1995 H HE2  . TYR A 1 145 ? 33.90000 20.77600 -5.61500  1.000 45.82000  ? 143 TYR A HE2  1 
ATOM   1996 H HH   . TYR A 1 145 ? 35.29500 23.78600 -5.36700  1.000 44.65000  ? 143 TYR A HH   1 
ATOM   1997 N N    . ILE A 1 146 ? 29.56500 18.86600 -0.43500  1.000 38.75000  ? 144 ILE A N    1 
ATOM   1998 C CA   . ILE A 1 146 ? 28.88900 17.90000 0.42500   1.000 43.85000  ? 144 ILE A CA   1 
ATOM   1999 C C    . ILE A 1 146 ? 28.73900 16.57200 -0.30300  1.000 38.79000  ? 144 ILE A C    1 
ATOM   2000 O O    . ILE A 1 146 ? 28.62900 16.52300 -1.53000  1.000 40.63000  ? 144 ILE A O    1 
ATOM   2001 C CB   . ILE A 1 146 ? 27.50400 18.42200 0.88000   1.000 40.50000  ? 144 ILE A CB   1 
ATOM   2002 C CG1  . ILE A 1 146 ? 27.66500 19.79900 1.53600   1.000 42.48000  ? 144 ILE A CG1  1 
ATOM   2003 C CG2  . ILE A 1 146 ? 26.84200 17.44400 1.82900   1.000 48.57000  ? 144 ILE A CG2  1 
ATOM   2004 C CD1  . ILE A 1 146 ? 26.48700 20.24400 2.37400   1.000 49.14000  ? 144 ILE A CD1  1 
ATOM   2005 H H    . ILE A 1 146 ? 29.31400 18.83200 -1.25700  1.000 46.35000  ? 144 ILE A H    1 
ATOM   2006 H HA   . ILE A 1 146 ? 29.42700 17.74900 1.21700   1.000 52.47000  ? 144 ILE A HA   1 
ATOM   2007 H HB   . ILE A 1 146 ? 26.94000 18.51900 0.09700   1.000 48.46000  ? 144 ILE A HB   1 
ATOM   2008 H HG12 . ILE A 1 146 ? 28.44300 19.77800 2.11300   1.000 50.83000  ? 144 ILE A HG12 1 
ATOM   2009 H HG13 . ILE A 1 146 ? 27.79400 20.46000 0.83800   1.000 50.83000  ? 144 ILE A HG13 1 
ATOM   2010 H HG21 . ILE A 1 146 ? 25.96000 17.76800 2.06700   1.000 58.13000  ? 144 ILE A HG21 1 
ATOM   2011 H HG22 . ILE A 1 146 ? 26.75100 16.58300 1.39500   1.000 58.13000  ? 144 ILE A HG22 1 
ATOM   2012 H HG23 . ILE A 1 146 ? 27.38900 17.35800 2.62500   1.000 58.13000  ? 144 ILE A HG23 1 
ATOM   2013 H HD11 . ILE A 1 146 ? 26.57000 21.19400 2.55300   1.000 58.82000  ? 144 ILE A HD11 1 
ATOM   2014 H HD12 . ILE A 1 146 ? 25.66900 20.07000 1.88400   1.000 58.82000  ? 144 ILE A HD12 1 
ATOM   2015 H HD13 . ILE A 1 146 ? 26.48600 19.74800 3.20700   1.000 58.82000  ? 144 ILE A HD13 1 
ATOM   2016 N N    . TYR A 1 147 ? 28.74800 15.48700 0.47000   1.000 44.62000  ? 145 TYR A N    1 
ATOM   2017 C CA   . TYR A 1 147 ? 28.46100 14.15900 -0.05900  1.000 46.63000  ? 145 TYR A CA   1 
ATOM   2018 C C    . TYR A 1 147 ? 27.74700 13.35300 1.01900   1.000 51.94000  ? 145 TYR A C    1 
ATOM   2019 O O    . TYR A 1 147 ? 27.80100 13.68100 2.20800   1.000 48.91000  ? 145 TYR A O    1 
ATOM   2020 C CB   . TYR A 1 147 ? 29.73600 13.45500 -0.55100  1.000 45.36000  ? 145 TYR A CB   1 
ATOM   2021 C CG   . TYR A 1 147 ? 30.61300 12.81800 0.50500   1.000 42.28000  ? 145 TYR A CG   1 
ATOM   2022 C CD1  . TYR A 1 147 ? 31.51300 13.56900 1.24100   1.000 39.95000  ? 145 TYR A CD1  1 
ATOM   2023 C CD2  . TYR A 1 147 ? 30.56900 11.44900 0.73100   1.000 50.90000  ? 145 TYR A CD2  1 
ATOM   2024 C CE1  . TYR A 1 147 ? 32.32400 12.98400 2.19400   1.000 43.05000  ? 145 TYR A CE1  1 
ATOM   2025 C CE2  . TYR A 1 147 ? 31.37500 10.85300 1.67900   1.000 48.10000  ? 145 TYR A CE2  1 
ATOM   2026 C CZ   . TYR A 1 147 ? 32.24900 11.62200 2.40800   1.000 47.02000  ? 145 TYR A CZ   1 
ATOM   2027 O OH   . TYR A 1 147 ? 33.05300 11.02000 3.35000   1.000 42.70000  ? 145 TYR A OH   1 
ATOM   2028 H H    . TYR A 1 147 ? 28.92000 15.49600 1.31300   1.000 53.39000  ? 145 TYR A H    1 
ATOM   2029 H HA   . TYR A 1 147 ? 27.86000 14.24600 -0.81400  1.000 55.81000  ? 145 TYR A HA   1 
ATOM   2030 H HB2  . TYR A 1 147 ? 29.47600 12.75400 -1.16800  1.000 54.28000  ? 145 TYR A HB2  1 
ATOM   2031 H HB3  . TYR A 1 147 ? 30.28100 14.10700 -1.01900  1.000 54.28000  ? 145 TYR A HB3  1 
ATOM   2032 H HD1  . TYR A 1 147 ? 31.56300 14.48700 1.10000   1.000 47.79000  ? 145 TYR A HD1  1 
ATOM   2033 H HD2  . TYR A 1 147 ? 29.97700 10.92400 0.24200   1.000 60.93000  ? 145 TYR A HD2  1 
ATOM   2034 H HE1  . TYR A 1 147 ? 32.91800 13.50400 2.68700   1.000 51.51000  ? 145 TYR A HE1  1 
ATOM   2035 H HE2  . TYR A 1 147 ? 31.32700 9.93600  1.82500   1.000 57.57000  ? 145 TYR A HE2  1 
ATOM   2036 H HH   . TYR A 1 147 ? 32.90100 10.19400 3.37200   1.000 51.09000  ? 145 TYR A HH   1 
ATOM   2037 N N    . LYS A 1 148 ? 27.04700 12.30600 0.58600   1.000 52.98000  ? 146 LYS A N    1 
ATOM   2038 C CA   . LYS A 1 148 ? 26.27200 11.46700 1.49000   1.000 55.04000  ? 146 LYS A CA   1 
ATOM   2039 C C    . LYS A 1 148 ? 27.01600 10.16400 1.74600   1.000 51.91000  ? 146 LYS A C    1 
ATOM   2040 O O    . LYS A 1 148 ? 27.38000 9.45400  0.80300   1.000 54.61000  ? 146 LYS A O    1 
ATOM   2041 C CB   . LYS A 1 148 ? 24.88300 11.16600 0.92800   1.000 57.98000  ? 146 LYS A CB   1 
ATOM   2042 C CG   . LYS A 1 148 ? 23.91000 10.65600 1.98900   1.000 69.55000  ? 146 LYS A CG   1 
ATOM   2043 C CD   . LYS A 1 148 ? 22.54800 10.30700 1.40900   1.000 76.80000  ? 146 LYS A CD   1 
ATOM   2044 C CE   . LYS A 1 148 ? 21.49900 11.34200 1.79800   1.000 82.90000  ? 146 LYS A CE   1 
ATOM   2045 N NZ   . LYS A 1 148 ? 20.54200 10.83500 2.82500   1.000 94.40000  ? 146 LYS A NZ   1 
ATOM   2046 H H    . LYS A 1 148 ? 27.00600 12.06000 -0.23700  1.000 63.43000  ? 146 LYS A H    1 
ATOM   2047 H HA   . LYS A 1 148 ? 26.16100 11.92400 2.33800   1.000 65.90000  ? 146 LYS A HA   1 
ATOM   2048 H HB2  . LYS A 1 148 ? 24.51300 11.98000 0.54900   1.000 69.43000  ? 146 LYS A HB2  1 
ATOM   2049 H HB3  . LYS A 1 148 ? 24.96100 10.48600 0.24100   1.000 69.43000  ? 146 LYS A HB3  1 
ATOM   2050 H HG2  . LYS A 1 148 ? 24.27700 9.84900  2.38200   1.000 83.32000  ? 146 LYS A HG2  1 
ATOM   2051 H HG3  . LYS A 1 148 ? 23.80200 11.33300 2.67400   1.000 83.32000  ? 146 LYS A HG3  1 
ATOM   2052 H HD2  . LYS A 1 148 ? 22.60800 10.28200 0.44100   1.000 92.01000  ? 146 LYS A HD2  1 
ATOM   2053 H HD3  . LYS A 1 148 ? 22.26600 9.44400  1.75100   1.000 92.01000  ? 146 LYS A HD3  1 
ATOM   2054 H HE2  . LYS A 1 148 ? 21.94600 12.11000 2.17300   1.000 99.33000  ? 146 LYS A HE2  1 
ATOM   2055 H HE3  . LYS A 1 148 ? 20.99400 11.59800 1.01100   1.000 99.33000  ? 146 LYS A HE3  1 
ATOM   2056 H HZ1  . LYS A 1 148 ? 19.94800 11.46700 3.02400   1.000 113.14000 ? 146 LYS A HZ1  1 
ATOM   2057 H HZ2  . LYS A 1 148 ? 20.11200 10.12200 2.51400   1.000 113.14000 ? 146 LYS A HZ2  1 
ATOM   2058 H HZ3  . LYS A 1 148 ? 20.98200 10.60800 3.56500   1.000 113.14000 ? 146 LYS A HZ3  1 
ATOM   2059 N N    . ARG A 1 149 ? 27.23600 9.85800  3.02200   1.000 59.42000  ? 147 ARG A N    1 
ATOM   2060 C CA   . ARG A 1 149 ? 27.87200 8.62100  3.46100   1.000 62.31000  ? 147 ARG A CA   1 
ATOM   2061 C C    . ARG A 1 149 ? 26.86600 7.85600  4.31100   1.000 69.36000  ? 147 ARG A C    1 
ATOM   2062 O O    . ARG A 1 149 ? 26.45500 8.33700  5.37400   1.000 65.95000  ? 147 ARG A O    1 
ATOM   2063 C CB   . ARG A 1 149 ? 29.14400 8.91500  4.25300   1.000 55.85000  ? 147 ARG A CB   1 
ATOM   2064 C CG   . ARG A 1 149 ? 29.92000 7.68400  4.68500   1.000 60.44000  ? 147 ARG A CG   1 
ATOM   2065 C CD   . ARG A 1 149 ? 31.22800 8.08000  5.36500   1.000 55.53000  ? 147 ARG A CD   1 
ATOM   2066 N NE   . ARG A 1 149 ? 31.00200 8.87700  6.56600   1.000 56.51000  ? 147 ARG A NE   1 
ATOM   2067 C CZ   . ARG A 1 149 ? 31.83400 9.80400  7.02400   1.000 56.28000  ? 147 ARG A CZ   1 
ATOM   2068 N NH1  . ARG A 1 149 ? 32.96700 10.09100 6.39700   1.000 55.53000  ? 147 ARG A NH1  1 
ATOM   2069 N NH2  . ARG A 1 149 ? 31.52500 10.46100 8.13800   1.000 55.18000  ? 147 ARG A NH2  1 
ATOM   2070 H H    . ARG A 1 149 ? 27.01600 10.37300 3.67600   1.000 71.15000  ? 147 ARG A H    1 
ATOM   2071 H HA   . ARG A 1 149 ? 28.10500 8.07900  2.69100   1.000 74.62000  ? 147 ARG A HA   1 
ATOM   2072 H HB2  . ARG A 1 149 ? 29.73300 9.45500  3.70300   1.000 66.87000  ? 147 ARG A HB2  1 
ATOM   2073 H HB3  . ARG A 1 149 ? 28.90300 9.40700  5.05400   1.000 66.87000  ? 147 ARG A HB3  1 
ATOM   2074 H HG2  . ARG A 1 149 ? 29.38900 7.17300  5.31500   1.000 72.38000  ? 147 ARG A HG2  1 
ATOM   2075 H HG3  . ARG A 1 149 ? 30.13000 7.14700  3.90600   1.000 72.38000  ? 147 ARG A HG3  1 
ATOM   2076 H HD2  . ARG A 1 149 ? 31.70900 7.27800  5.62000   1.000 66.49000  ? 147 ARG A HD2  1 
ATOM   2077 H HD3  . ARG A 1 149 ? 31.75500 8.60300  4.74200   1.000 66.49000  ? 147 ARG A HD3  1 
ATOM   2078 H HE   . ARG A 1 149 ? 30.27900 8.73600  7.01000   1.000 67.66000  ? 147 ARG A HE   1 
ATOM   2079 H HH11 . ARG A 1 149 ? 33.18200 9.67500  5.67600   1.000 66.49000  ? 147 ARG A HH11 1 
ATOM   2080 H HH12 . ARG A 1 149 ? 33.48900 10.69500 6.71300   1.000 66.49000  ? 147 ARG A HH12 1 
ATOM   2081 H HH21 . ARG A 1 149 ? 30.79300 10.28400 8.55300   1.000 66.06000  ? 147 ARG A HH21 1 
ATOM   2082 H HH22 . ARG A 1 149 ? 32.05600 11.06500 8.44400   1.000 66.06000  ? 147 ARG A HH22 1 
ATOM   2083 N N    . GLY A 1 150 ? 26.47000 6.68000  3.84300   1.000 76.32000  ? 148 GLY A N    1 
ATOM   2084 C CA   . GLY A 1 150 ? 25.41400 5.94800  4.52200   1.000 69.53000  ? 148 GLY A CA   1 
ATOM   2085 C C    . GLY A 1 150 ? 24.13400 6.75900  4.48400   1.000 76.85000  ? 148 GLY A C    1 
ATOM   2086 O O    . GLY A 1 150 ? 23.58800 7.06200  3.41400   1.000 79.43000  ? 148 GLY A O    1 
ATOM   2087 H H    . GLY A 1 150 ? 26.79100 6.29000  3.14700   1.000 91.44000  ? 148 GLY A H    1 
ATOM   2088 H HA2  . GLY A 1 150 ? 25.26300 5.09700  4.08100   1.000 83.29000  ? 148 GLY A HA2  1 
ATOM   2089 H HA3  . GLY A 1 150 ? 25.66000 5.78800  5.44600   1.000 83.29000  ? 148 GLY A HA3  1 
ATOM   2090 N N    . ASN A 1 151 ? 23.64100 7.13100  5.66000   1.000 77.32000  ? 149 ASN A N    1 
ATOM   2091 C CA   . ASN A 1 151 ? 22.48600 8.00700  5.77100   1.000 87.41000  ? 149 ASN A CA   1 
ATOM   2092 C C    . ASN A 1 151 ? 22.86300 9.42700  6.16700   1.000 86.63000  ? 149 ASN A C    1 
ATOM   2093 O O    . ASN A 1 151 ? 21.98000 10.28500 6.26000   1.000 90.19000  ? 149 ASN A O    1 
ATOM   2094 C CB   . ASN A 1 151 ? 21.49400 7.44000  6.79000   1.000 97.42000  ? 149 ASN A CB   1 
ATOM   2095 C CG   . ASN A 1 151 ? 20.41500 6.60500  6.14100   1.000 106.50000 ? 149 ASN A CG   1 
ATOM   2096 O OD1  . ASN A 1 151 ? 19.48400 7.13700  5.53400   1.000 109.22000 ? 149 ASN A OD1  1 
ATOM   2097 N ND2  . ASN A 1 151 ? 20.54000 5.28600  6.25600   1.000 106.16000 ? 149 ASN A ND2  1 
ATOM   2098 H H    . ASN A 1 151 ? 23.96400 6.88500  6.41800   1.000 92.63000  ? 149 ASN A H    1 
ATOM   2099 H HA   . ASN A 1 151 ? 22.03700 8.05000  4.91300   1.000 104.75000 ? 149 ASN A HA   1 
ATOM   2100 H HB2  . ASN A 1 151 ? 21.97300 6.87800  7.41900   1.000 116.75000 ? 149 ASN A HB2  1 
ATOM   2101 H HB3  . ASN A 1 151 ? 21.06600 8.17400  7.25800   1.000 116.75000 ? 149 ASN A HB3  1 
ATOM   2102 H HD21 . ASN A 1 151 ? 21.20600 4.95300  6.68600   1.000 127.25000 ? 149 ASN A HD21 1 
ATOM   2103 H HD22 . ASN A 1 151 ? 19.95200 4.76700  5.90300   1.000 127.25000 ? 149 ASN A HD22 1 
ATOM   2104 N N    . ASP A 1 152 ? 24.14600 9.69700  6.38600   1.000 79.85000  ? 150 ASP A N    1 
ATOM   2105 C CA   . ASP A 1 152 ? 24.60100 10.98000 6.90500   1.000 76.91000  ? 150 ASP A CA   1 
ATOM   2106 C C    . ASP A 1 152 ? 25.14400 11.85700 5.78500   1.000 68.46000  ? 150 ASP A C    1 
ATOM   2107 O O    . ASP A 1 152 ? 25.87200 11.38400 4.90800   1.000 62.32000  ? 150 ASP A O    1 
ATOM   2108 C CB   . ASP A 1 152 ? 25.68600 10.77400 7.96900   1.000 70.43000  ? 150 ASP A CB   1 
ATOM   2109 C CG   . ASP A 1 152 ? 25.16300 10.07900 9.21300   1.000 77.88000  ? 150 ASP A CG   1 
ATOM   2110 O OD1  . ASP A 1 152 ? 23.94200 9.83100  9.29100   1.000 82.62000  ? 150 ASP A OD1  1 
ATOM   2111 O OD2  . ASP A 1 152 ? 25.97700 9.78100  10.11400  1.000 81.11000  ? 150 ASP A OD2  1 
ATOM   2112 H H    . ASP A 1 152 ? 24.78600 9.14200  6.23900   1.000 95.67000  ? 150 ASP A H    1 
ATOM   2113 H HA   . ASP A 1 152 ? 23.85500 11.44200 7.31800   1.000 92.14000  ? 150 ASP A HA   1 
ATOM   2114 H HB2  . ASP A 1 152 ? 26.39500 10.22800 7.59600   1.000 84.37000  ? 150 ASP A HB2  1 
ATOM   2115 H HB3  . ASP A 1 152 ? 26.03700 11.63900 8.23400   1.000 84.37000  ? 150 ASP A HB3  1 
ATOM   2116 N N    . TYR A 1 153 ? 24.77400 13.13800 5.81900   1.000 68.82000  ? 151 TYR A N    1 
ATOM   2117 C CA   . TYR A 1 153 ? 25.39300 14.13600 4.95900   1.000 53.87000  ? 151 TYR A CA   1 
ATOM   2118 C C    . TYR A 1 153 ? 26.68900 14.62200 5.59700   1.000 48.46000  ? 151 TYR A C    1 
ATOM   2119 O O    . TYR A 1 153 ? 26.75500 14.84400 6.80900   1.000 51.21000  ? 151 TYR A O    1 
ATOM   2120 C CB   . TYR A 1 153 ? 24.44500 15.31400 4.73900   1.000 66.22000  ? 151 TYR A CB   1 
ATOM   2121 C CG   . TYR A 1 153 ? 23.33000 15.04800 3.75200   1.000 70.84000  ? 151 TYR A CG   1 
ATOM   2122 C CD1  . TYR A 1 153 ? 23.59200 14.92900 2.39400   1.000 62.88000  ? 151 TYR A CD1  1 
ATOM   2123 C CD2  . TYR A 1 153 ? 22.01600 14.92000 4.18000   1.000 79.44000  ? 151 TYR A CD2  1 
ATOM   2124 C CE1  . TYR A 1 153 ? 22.57800 14.68600 1.48800   1.000 73.51000  ? 151 TYR A CE1  1 
ATOM   2125 C CE2  . TYR A 1 153 ? 20.99200 14.67600 3.28200   1.000 87.97000  ? 151 TYR A CE2  1 
ATOM   2126 C CZ   . TYR A 1 153 ? 21.27900 14.56800 1.93500   1.000 88.04000  ? 151 TYR A CZ   1 
ATOM   2127 O OH   . TYR A 1 153 ? 20.26700 14.31800 1.03400   1.000 96.79000  ? 151 TYR A OH   1 
ATOM   2128 H H    . TYR A 1 153 ? 24.16300 13.45200 6.33600   1.000 82.43000  ? 151 TYR A H    1 
ATOM   2129 H HA   . TYR A 1 153 ? 25.60000 13.74100 4.09800   1.000 64.50000  ? 151 TYR A HA   1 
ATOM   2130 H HB2  . TYR A 1 153 ? 24.03700 15.54600 5.58800   1.000 79.32000  ? 151 TYR A HB2  1 
ATOM   2131 H HB3  . TYR A 1 153 ? 24.95800 16.06700 4.40700   1.000 79.32000  ? 151 TYR A HB3  1 
ATOM   2132 H HD1  . TYR A 1 153 ? 24.46600 15.01200 2.08800   1.000 75.31000  ? 151 TYR A HD1  1 
ATOM   2133 H HD2  . TYR A 1 153 ? 21.82100 14.99800 5.08600   1.000 95.18000  ? 151 TYR A HD2  1 
ATOM   2134 H HE1  . TYR A 1 153 ? 22.76900 14.60900 0.58100   1.000 88.07000  ? 151 TYR A HE1  1 
ATOM   2135 H HE2  . TYR A 1 153 ? 20.11600 14.59200 3.58200   1.000 105.41000 ? 151 TYR A HE2  1 
ATOM   2136 H HH   . TYR A 1 153 ? 19.53100 14.27000 1.43600   1.000 116.01000 ? 151 TYR A HH   1 
ATOM   2137 N N    . VAL A 1 154 ? 27.72500 14.79200 4.77600   1.000 46.70000  ? 152 VAL A N    1 
ATOM   2138 C CA   . VAL A 1 154 ? 29.04400 15.20200 5.25200   1.000 44.86000  ? 152 VAL A CA   1 
ATOM   2139 C C    . VAL A 1 154 ? 29.50500 16.40500 4.43600   1.000 45.48000  ? 152 VAL A C    1 
ATOM   2140 O O    . VAL A 1 154 ? 29.58100 16.33000 3.20200   1.000 41.12000  ? 152 VAL A O    1 
ATOM   2141 C CB   . VAL A 1 154 ? 30.07100 14.05900 5.15000   1.000 46.06000  ? 152 VAL A CB   1 
ATOM   2142 C CG1  . VAL A 1 154 ? 31.45600 14.53300 5.57100   1.000 47.64000  ? 152 VAL A CG1  1 
ATOM   2143 C CG2  . VAL A 1 154 ? 29.63300 12.87000 5.99200   1.000 48.21000  ? 152 VAL A CG2  1 
ATOM   2144 H H    . VAL A 1 154 ? 27.68700 14.67300 3.92500   1.000 55.89000  ? 152 VAL A H    1 
ATOM   2145 H HA   . VAL A 1 154 ? 28.98200 15.47300 6.18100   1.000 53.68000  ? 152 VAL A HA   1 
ATOM   2146 H HB   . VAL A 1 154 ? 30.12400 13.76700 4.22700   1.000 55.13000  ? 152 VAL A HB   1 
ATOM   2147 H HG11 . VAL A 1 154 ? 32.02400 13.75900 5.70800   1.000 57.02000  ? 152 VAL A HG11 1 
ATOM   2148 H HG12 . VAL A 1 154 ? 31.82800 15.09400 4.87300   1.000 57.02000  ? 152 VAL A HG12 1 
ATOM   2149 H HG13 . VAL A 1 154 ? 31.38000 15.03600 6.39800   1.000 57.02000  ? 152 VAL A HG13 1 
ATOM   2150 H HG21 . VAL A 1 154 ? 30.30600 12.17400 5.92900   1.000 57.70000  ? 152 VAL A HG21 1 
ATOM   2151 H HG22 . VAL A 1 154 ? 29.53800 13.15500 6.91400   1.000 57.70000  ? 152 VAL A HG22 1 
ATOM   2152 H HG23 . VAL A 1 154 ? 28.78400 12.54100 5.65800   1.000 57.70000  ? 152 VAL A HG23 1 
ATOM   2153 N N    . VAL A 1 155 ? 29.81000 17.50900 5.11800   1.000 44.77000  ? 153 VAL A N    1 
ATOM   2154 C CA   . VAL A 1 155 ? 30.39900 18.67700 4.47300   1.000 38.21000  ? 153 VAL A CA   1 
ATOM   2155 C C    . VAL A 1 155 ? 31.91500 18.55400 4.57000   1.000 40.36000  ? 153 VAL A C    1 
ATOM   2156 O O    . VAL A 1 155 ? 32.45600 18.19300 5.62200   1.000 41.97000  ? 153 VAL A O    1 
ATOM   2157 C CB   . VAL A 1 155 ? 29.88900 19.98000 5.11400   1.000 39.15000  ? 153 VAL A CB   1 
ATOM   2158 C CG1  . VAL A 1 155 ? 30.22200 20.03500 6.58900   1.000 50.33000  ? 153 VAL A CG1  1 
ATOM   2159 C CG2  . VAL A 1 155 ? 30.48900 21.18000 4.39700   1.000 44.21000  ? 153 VAL A CG2  1 
ATOM   2160 H H    . VAL A 1 155 ? 29.68400 17.60300 5.96300   1.000 53.57000  ? 153 VAL A H    1 
ATOM   2161 H HA   . VAL A 1 155 ? 30.15400 18.68600 3.53500   1.000 45.70000  ? 153 VAL A HA   1 
ATOM   2162 H HB   . VAL A 1 155 ? 28.92400 20.02500 5.02000   1.000 46.83000  ? 153 VAL A HB   1 
ATOM   2163 H HG11 . VAL A 1 155 ? 29.98200 20.91100 6.92900   1.000 60.25000  ? 153 VAL A HG11 1 
ATOM   2164 H HG12 . VAL A 1 155 ? 29.71300 19.35400 7.05300   1.000 60.25000  ? 153 VAL A HG12 1 
ATOM   2165 H HG13 . VAL A 1 155 ? 31.17000 19.88600 6.71300   1.000 60.25000  ? 153 VAL A HG13 1 
ATOM   2166 H HG21 . VAL A 1 155 ? 30.04200 21.98300 4.70300   1.000 52.90000  ? 153 VAL A HG21 1 
ATOM   2167 H HG22 . VAL A 1 155 ? 31.43600 21.23100 4.60100   1.000 52.90000  ? 153 VAL A HG22 1 
ATOM   2168 H HG23 . VAL A 1 155 ? 30.35900 21.07300 3.44200   1.000 52.90000  ? 153 VAL A HG23 1 
ATOM   2169 N N    . ILE A 1 156 ? 32.60600 18.85500 3.47100   1.000 40.40000  ? 154 ILE A N    1 
ATOM   2170 C CA   . ILE A 1 156 ? 34.03600 18.57900 3.36200   1.000 40.57000  ? 154 ILE A CA   1 
ATOM   2171 C C    . ILE A 1 156 ? 34.87700 19.81500 3.09100   1.000 39.42000  ? 154 ILE A C    1 
ATOM   2172 O O    . ILE A 1 156 ? 36.11500 19.71100 3.10300   1.000 37.55000  ? 154 ILE A O    1 
ATOM   2173 C CB   . ILE A 1 156 ? 34.31600 17.51600 2.27300   1.000 42.95000  ? 154 ILE A CB   1 
ATOM   2174 C CG1  . ILE A 1 156 ? 33.87000 18.03000 0.90200   1.000 37.93000  ? 154 ILE A CG1  1 
ATOM   2175 C CG2  . ILE A 1 156 ? 33.60900 16.21900 2.61700   1.000 40.17000  ? 154 ILE A CG2  1 
ATOM   2176 C CD1  . ILE A 1 156 ? 34.27600 17.14500 -0.25300  1.000 39.49000  ? 154 ILE A CD1  1 
ATOM   2177 H H    . ILE A 1 156 ? 32.26600 19.22100 2.77100   1.000 48.33000  ? 154 ILE A H    1 
ATOM   2178 H HA   . ILE A 1 156 ? 34.34100 18.20900 4.20500   1.000 48.53000  ? 154 ILE A HA   1 
ATOM   2179 H HB   . ILE A 1 156 ? 35.27000 17.34900 2.24500   1.000 51.39000  ? 154 ILE A HB   1 
ATOM   2180 H HG12 . ILE A 1 156 ? 32.90200 18.09600 0.89600   1.000 45.36000  ? 154 ILE A HG12 1 
ATOM   2181 H HG13 . ILE A 1 156 ? 34.25800 18.90400 0.74500   1.000 45.36000  ? 154 ILE A HG13 1 
ATOM   2182 H HG21 . ILE A 1 156 ? 33.88700 15.53100 1.99300   1.000 48.05000  ? 154 ILE A HG21 1 
ATOM   2183 H HG22 . ILE A 1 156 ? 33.84700 15.96000 3.52100   1.000 48.05000  ? 154 ILE A HG22 1 
ATOM   2184 H HG23 . ILE A 1 156 ? 32.65100 16.35600 2.55400   1.000 48.05000  ? 154 ILE A HG23 1 
ATOM   2185 H HD11 . ILE A 1 156 ? 34.03000 17.58100 -1.08500  1.000 47.24000  ? 154 ILE A HD11 1 
ATOM   2186 H HD12 . ILE A 1 156 ? 35.23600 17.00800 -0.22200  1.000 47.24000  ? 154 ILE A HD12 1 
ATOM   2187 H HD13 . ILE A 1 156 ? 33.81700 16.29500 -0.17600  1.000 47.24000  ? 154 ILE A HD13 1 
ATOM   2188 N N    . GLY A 1 157 ? 34.27200 20.96400 2.83000   1.000 33.43000  ? 155 GLY A N    1 
ATOM   2189 C CA   . GLY A 1 157 ? 35.03800 22.16600 2.57800   1.000 34.74000  ? 155 GLY A CA   1 
ATOM   2190 C C    . GLY A 1 157 ? 34.19800 23.18400 1.83200   1.000 34.22000  ? 155 GLY A C    1 
ATOM   2191 O O    . GLY A 1 157 ? 32.99600 23.00500 1.64200   1.000 34.75000  ? 155 GLY A O    1 
ATOM   2192 H H    . GLY A 1 157 ? 33.42000 21.07300 2.79400   1.000 39.96000  ? 155 GLY A H    1 
ATOM   2193 H HA2  . GLY A 1 157 ? 35.31900 22.55600 3.42000   1.000 41.54000  ? 155 GLY A HA2  1 
ATOM   2194 H HA3  . GLY A 1 157 ? 35.82600 21.95800 2.05500   1.000 41.54000  ? 155 GLY A HA3  1 
ATOM   2195 N N    . VAL A 1 158 ? 34.87200 24.24800 1.39800   1.000 34.46000  ? 156 VAL A N    1 
ATOM   2196 C CA   . VAL A 1 158 ? 34.22400 25.37200 0.74200   1.000 29.61000  ? 156 VAL A CA   1 
ATOM   2197 C C    . VAL A 1 158 ? 34.95300 25.71100 -0.54600  1.000 32.89000  ? 156 VAL A C    1 
ATOM   2198 O O    . VAL A 1 158 ? 36.17100 25.54400 -0.66200  1.000 33.35000  ? 156 VAL A O    1 
ATOM   2199 C CB   . VAL A 1 158 ? 34.17400 26.61200 1.66000   1.000 32.56000  ? 156 VAL A CB   1 
ATOM   2200 C CG1  . VAL A 1 158 ? 33.37700 26.30000 2.90900   1.000 31.91000  ? 156 VAL A CG1  1 
ATOM   2201 C CG2  . VAL A 1 158 ? 35.58200 27.06700 2.00500   1.000 34.68000  ? 156 VAL A CG2  1 
ATOM   2202 H H    . VAL A 1 158 ? 35.72400 24.34000 1.47500   1.000 41.20000  ? 156 VAL A H    1 
ATOM   2203 H HA   . VAL A 1 158 ? 33.31300 25.12800 0.51600   1.000 35.39000  ? 156 VAL A HA   1 
ATOM   2204 H HB   . VAL A 1 158 ? 33.72900 27.33600 1.19200   1.000 38.92000  ? 156 VAL A HB   1 
ATOM   2205 H HG11 . VAL A 1 158 ? 33.31800 27.10000 3.45400   1.000 38.15000  ? 156 VAL A HG11 1 
ATOM   2206 H HG12 . VAL A 1 158 ? 32.48800 26.00900 2.65100   1.000 38.15000  ? 156 VAL A HG12 1 
ATOM   2207 H HG13 . VAL A 1 158 ? 33.82600 25.59500 3.40300   1.000 38.15000  ? 156 VAL A HG13 1 
ATOM   2208 H HG21 . VAL A 1 158 ? 35.53200 27.74100 2.70000   1.000 41.47000  ? 156 VAL A HG21 1 
ATOM   2209 H HG22 . VAL A 1 158 ? 36.09400 26.30500 2.32100   1.000 41.47000  ? 156 VAL A HG22 1 
ATOM   2210 H HG23 . VAL A 1 158 ? 36.00000 27.44000 1.21300   1.000 41.47000  ? 156 VAL A HG23 1 
ATOM   2211 N N    . HIS A 1 159 ? 34.19500 26.22900 -1.50400  1.000 30.88000  ? 157 HIS A N    1 
ATOM   2212 C CA   . HIS A 1 159 ? 34.74000 26.52700 -2.81900  1.000 31.86000  ? 157 HIS A CA   1 
ATOM   2213 C C    . HIS A 1 159 ? 35.63500 27.75500 -2.76500  1.000 34.73000  ? 157 HIS A C    1 
ATOM   2214 O O    . HIS A 1 159 ? 35.24900 28.79500 -2.21900  1.000 33.30000  ? 157 HIS A O    1 
ATOM   2215 C CB   . HIS A 1 159 ? 33.61600 26.76100 -3.82700  1.000 39.25000  ? 157 HIS A CB   1 
ATOM   2216 C CG   . HIS A 1 159 ? 34.10800 26.97700 -5.22100  1.000 34.29000  ? 157 HIS A CG   1 
ATOM   2217 N ND1  . HIS A 1 159 ? 34.71200 25.97800 -5.95300  1.000 32.61000  ? 157 HIS A ND1  1 
ATOM   2218 C CD2  . HIS A 1 159 ? 34.10700 28.07800 -6.00800  1.000 36.23000  ? 157 HIS A CD2  1 
ATOM   2219 C CE1  . HIS A 1 159 ? 35.05400 26.45300 -7.13700  1.000 35.66000  ? 157 HIS A CE1  1 
ATOM   2220 N NE2  . HIS A 1 159 ? 34.69700 27.72500 -7.19600  1.000 41.21000  ? 157 HIS A NE2  1 
ATOM   2221 H H    . HIS A 1 159 ? 33.36000 26.41600 -1.41700  1.000 36.91000  ? 157 HIS A H    1 
ATOM   2222 H HA   . HIS A 1 159 ? 35.27500 25.77800 -3.12400  1.000 38.09000  ? 157 HIS A HA   1 
ATOM   2223 H HB2  . HIS A 1 159 ? 33.03700 25.98400 -3.83200  1.000 46.95000  ? 157 HIS A HB2  1 
ATOM   2224 H HB3  . HIS A 1 159 ? 33.11300 27.54700 -3.56200  1.000 46.95000  ? 157 HIS A HB3  1 
ATOM   2225 H HD2  . HIS A 1 159 ? 33.76600 28.91500 -5.78800  1.000 43.33000  ? 157 HIS A HD2  1 
ATOM   2226 H HE1  . HIS A 1 159 ? 35.47300 25.97300 -7.81500  1.000 42.65000  ? 157 HIS A HE1  1 
ATOM   2227 H HE2  . HIS A 1 159 ? 34.81500 28.24600 -7.87000  1.000 49.30000  ? 157 HIS A HE2  1 
ATOM   2228 N N    . THR A 1 160 ? 36.82100 27.63900 -3.36200  1.000 37.45000  ? 158 THR A N    1 
ATOM   2229 C CA   . THR A 1 160 ? 37.79800 28.70900 -3.35700  1.000 33.21000  ? 158 THR A CA   1 
ATOM   2230 C C    . THR A 1 160 ? 38.46400 28.98400 -4.70100  1.000 35.70000  ? 158 THR A C    1 
ATOM   2231 O O    . THR A 1 160 ? 38.97400 30.09500 -4.88200  1.000 33.04000  ? 158 THR A O    1 
ATOM   2232 C CB   . THR A 1 160 ? 38.91600 28.42200 -2.33300  1.000 43.63000  ? 158 THR A CB   1 
ATOM   2233 O OG1  . THR A 1 160 ? 39.61800 27.23000 -2.71500  1.000 45.91000  ? 158 THR A OG1  1 
ATOM   2234 C CG2  . THR A 1 160 ? 38.33000 28.23200 -0.94500  1.000 48.52000  ? 158 THR A CG2  1 
ATOM   2235 H H    . THR A 1 160 ? 37.08100 26.93500 -3.78300  1.000 44.80000  ? 158 THR A H    1 
ATOM   2236 H HA   . THR A 1 160 ? 37.35600 29.52800 -3.08300  1.000 39.70000  ? 158 THR A HA   1 
ATOM   2237 H HB   . THR A 1 160 ? 39.53400 29.17000 -2.30900  1.000 52.21000  ? 158 THR A HB   1 
ATOM   2238 H HG1  . THR A 1 160 ? 40.22900 27.06800 -2.16100  1.000 54.95000  ? 158 THR A HG1  1 
ATOM   2239 H HG21 . THR A 1 160 ? 39.03800 28.17300 -0.29200  1.000 58.07000  ? 158 THR A HG21 1 
ATOM   2240 H HG22 . THR A 1 160 ? 37.75800 28.98300 -0.72200  1.000 58.07000  ? 158 THR A HG22 1 
ATOM   2241 H HG23 . THR A 1 160 ? 37.80500 27.41700 -0.91500  1.000 58.07000  ? 158 THR A HG23 1 
ATOM   2242 N N    . ALA A 1 161 ? 38.47100 28.03300 -5.63500  1.000 36.29000  ? 159 ALA A N    1 
ATOM   2243 C CA   . ALA A 1 161 ? 39.13200 28.29300 -6.91000  1.000 35.33000  ? 159 ALA A CA   1 
ATOM   2244 C C    . ALA A 1 161 ? 38.66400 27.31200 -7.97500  1.000 36.10000  ? 159 ALA A C    1 
ATOM   2245 O O    . ALA A 1 161 ? 38.10900 26.25400 -7.67600  1.000 33.93000  ? 159 ALA A O    1 
ATOM   2246 C CB   . ALA A 1 161 ? 40.66200 28.22100 -6.77400  1.000 34.94000  ? 159 ALA A CB   1 
ATOM   2247 H H    . ALA A 1 161 ? 38.11400 27.25500 -5.55800  1.000 43.41000  ? 159 ALA A H    1 
ATOM   2248 H HA   . ALA A 1 161 ? 38.90100 29.18700 -7.20700  1.000 42.24000  ? 159 ALA A HA   1 
ATOM   2249 H HB1  . ALA A 1 161 ? 41.06400 28.41700 -7.63500  1.000 41.78000  ? 159 ALA A HB1  1 
ATOM   2250 H HB2  . ALA A 1 161 ? 40.95100 28.87300 -6.11800  1.000 41.78000  ? 159 ALA A HB2  1 
ATOM   2251 H HB3  . ALA A 1 161 ? 40.91300 27.33000 -6.48700  1.000 41.78000  ? 159 ALA A HB3  1 
ATOM   2252 N N    . ALA A 1 162 ? 38.90100 27.69100 -9.23100  1.000 42.35000  ? 160 ALA A N    1 
ATOM   2253 C CA   . ALA A 1 162 ? 38.65000 26.82400 -10.37300 1.000 46.17000  ? 160 ALA A CA   1 
ATOM   2254 C C    . ALA A 1 162 ? 39.69200 27.15300 -11.43300 1.000 44.97000  ? 160 ALA A C    1 
ATOM   2255 O O    . ALA A 1 162 ? 39.98000 28.32400 -11.68300 1.000 40.90000  ? 160 ALA A O    1 
ATOM   2256 C CB   . ALA A 1 162 ? 37.23700 27.00400 -10.93200 1.000 41.33000  ? 160 ALA A CB   1 
ATOM   2257 H H    . ALA A 1 162 ? 39.21300 28.46200 -9.44700  1.000 50.68000  ? 160 ALA A H    1 
ATOM   2258 H HA   . ALA A 1 162 ? 38.76200 25.89800 -10.10800 1.000 55.26000  ? 160 ALA A HA   1 
ATOM   2259 H HB1  . ALA A 1 162 ? 37.12600 27.92500 -11.21900 1.000 49.45000  ? 160 ALA A HB1  1 
ATOM   2260 H HB2  . ALA A 1 162 ? 37.11600 26.40500 -11.68500 1.000 49.45000  ? 160 ALA A HB2  1 
ATOM   2261 H HB3  . ALA A 1 162 ? 36.59500 26.79500 -10.23600 1.000 49.45000  ? 160 ALA A HB3  1 
ATOM   2262 N N    . ALA A 1 163 ? 40.26000 26.12200 -12.04100 1.000 46.60000  ? 161 ALA A N    1 
ATOM   2263 C CA   . ALA A 1 163 ? 41.34600 26.32300 -12.98800 1.000 46.90000  ? 161 ALA A CA   1 
ATOM   2264 C C    . ALA A 1 163 ? 40.80400 26.74000 -14.34800 1.000 51.13000  ? 161 ALA A C    1 
ATOM   2265 O O    . ALA A 1 163 ? 39.75300 26.26600 -14.79300 1.000 50.37000  ? 161 ALA A O    1 
ATOM   2266 C CB   . ALA A 1 163 ? 42.17600 25.04700 -13.12500 1.000 45.74000  ? 161 ALA A CB   1 
ATOM   2267 H H    . ALA A 1 163 ? 40.03700 25.30000 -11.92300 1.000 55.77000  ? 161 ALA A H    1 
ATOM   2268 H HA   . ALA A 1 163 ? 41.92700 27.02800 -12.66400 1.000 56.13000  ? 161 ALA A HA   1 
ATOM   2269 H HB1  . ALA A 1 163 ? 42.89200 25.20500 -13.76100 1.000 54.74000  ? 161 ALA A HB1  1 
ATOM   2270 H HB2  . ALA A 1 163 ? 42.54600 24.81700 -12.25900 1.000 54.74000  ? 161 ALA A HB2  1 
ATOM   2271 H HB3  . ALA A 1 163 ? 41.60300 24.33100 -13.44200 1.000 54.74000  ? 161 ALA A HB3  1 
ATOM   2272 N N    . ARG A 1 164 ? 41.52200 27.65100 -14.99900 1.000 54.46000  ? 162 ARG A N    1 
ATOM   2273 C CA   . ARG A 1 164 ? 41.20800 27.99400 -16.37700 1.000 55.71000  ? 162 ARG A CA   1 
ATOM   2274 C C    . ARG A 1 164 ? 41.62800 26.85200 -17.29400 1.000 58.05000  ? 162 ARG A C    1 
ATOM   2275 O O    . ARG A 1 164 ? 42.55100 26.08800 -16.99400 1.000 56.27000  ? 162 ARG A O    1 
ATOM   2276 C CB   . ARG A 1 164 ? 41.91000 29.28600 -16.78500 1.000 59.79000  ? 162 ARG A CB   1 
ATOM   2277 C CG   . ARG A 1 164 ? 41.14100 30.54900 -16.41900 1.000 67.51000  ? 162 ARG A CG   1 
ATOM   2278 C CD   . ARG A 1 164 ? 41.81900 31.80600 -16.95800 1.000 66.45000  ? 162 ARG A CD   1 
ATOM   2279 N NE   . ARG A 1 164 ? 42.68000 32.42800 -15.95900 1.000 80.25000  ? 162 ARG A NE   1 
ATOM   2280 C CZ   . ARG A 1 164 ? 42.50900 33.65000 -15.46300 1.000 87.79000  ? 162 ARG A CZ   1 
ATOM   2281 N NH1  . ARG A 1 164 ? 41.51500 34.43000 -15.86400 1.000 86.24000  ? 162 ARG A NH1  1 
ATOM   2282 N NH2  . ARG A 1 164 ? 43.36000 34.10100 -14.54400 1.000 85.35000  ? 162 ARG A NH2  1 
ATOM   2283 H H    . ARG A 1 164 ? 42.18400 28.08300 -14.66500 1.000 65.21000  ? 162 ARG A H    1 
ATOM   2284 H HA   . ARG A 1 164 ? 40.25100 28.12400 -16.46700 1.000 66.71000  ? 162 ARG A HA   1 
ATOM   2285 H HB2  . ARG A 1 164 ? 42.77300 29.32500 -16.34400 1.000 71.60000  ? 162 ARG A HB2  1 
ATOM   2286 H HB3  . ARG A 1 164 ? 42.03400 29.28200 -17.74700 1.000 71.60000  ? 162 ARG A HB3  1 
ATOM   2287 H HG2  . ARG A 1 164 ? 40.25000 30.50000 -16.79700 1.000 80.86000  ? 162 ARG A HG2  1 
ATOM   2288 H HG3  . ARG A 1 164 ? 41.09100 30.62200 -15.45300 1.000 80.86000  ? 162 ARG A HG3  1 
ATOM   2289 H HD2  . ARG A 1 164 ? 42.37400 31.56100 -17.71500 1.000 79.60000  ? 162 ARG A HD2  1 
ATOM   2290 H HD3  . ARG A 1 164 ? 41.13700 32.43100 -17.24100 1.000 79.60000  ? 162 ARG A HD3  1 
ATOM   2291 H HE   . ARG A 1 164 ? 43.34700 31.97100 -15.66900 1.000 96.15000  ? 162 ARG A HE   1 
ATOM   2292 H HH11 . ARG A 1 164 ? 40.95400 34.16100 -16.45500 1.000 103.35000 ? 162 ARG A HH11 1 
ATOM   2293 H HH12 . ARG A 1 164 ? 41.43000 35.21600 -15.52500 1.000 103.35000 ? 162 ARG A HH12 1 
ATOM   2294 H HH21 . ARG A 1 164 ? 44.00900 33.60300 -14.27800 1.000 102.27000 ? 162 ARG A HH21 1 
ATOM   2295 H HH22 . ARG A 1 164 ? 43.26100 34.89000 -14.21600 1.000 102.27000 ? 162 ARG A HH22 1 
ATOM   2296 N N    . GLY A 1 165 ? 40.93300 26.73600 -18.42000 1.000 60.19000  ? 163 GLY A N    1 
ATOM   2297 C CA   . GLY A 1 165 ? 41.21500 25.68400 -19.37200 1.000 60.72000  ? 163 GLY A CA   1 
ATOM   2298 C C    . GLY A 1 165 ? 41.03100 24.30800 -18.77000 1.000 68.87000  ? 163 GLY A C    1 
ATOM   2299 O O    . GLY A 1 165 ? 41.89400 23.43500 -18.92400 1.000 71.25000  ? 163 GLY A O    1 
ATOM   2300 H H    . GLY A 1 165 ? 40.29100 27.26000 -18.65200 1.000 72.09000  ? 163 GLY A H    1 
ATOM   2301 H HA2  . GLY A 1 165 ? 40.62100 25.76800 -20.13400 1.000 72.72000  ? 163 GLY A HA2  1 
ATOM   2302 H HA3  . GLY A 1 165 ? 42.13000 25.76500 -19.68200 1.000 72.72000  ? 163 GLY A HA3  1 
ATOM   2303 N N    . GLY A 1 166 ? 39.91400 24.10400 -18.08200 1.000 59.23000  ? 164 GLY A N    1 
ATOM   2304 C CA   . GLY A 1 166 ? 39.64600 22.82300 -17.46000 1.000 56.51000  ? 164 GLY A CA   1 
ATOM   2305 C C    . GLY A 1 166 ? 38.45100 22.91700 -16.54100 1.000 55.34000  ? 164 GLY A C    1 
ATOM   2306 O O    . GLY A 1 166 ? 37.91800 23.99900 -16.27000 1.000 54.09000  ? 164 GLY A O    1 
ATOM   2307 H H    . GLY A 1 166 ? 39.29900 24.69300 -17.96200 1.000 70.93000  ? 164 GLY A H    1 
ATOM   2308 H HA2  . GLY A 1 166 ? 39.46500 22.15800 -18.14200 1.000 67.67000  ? 164 GLY A HA2  1 
ATOM   2309 H HA3  . GLY A 1 166 ? 40.41700 22.54000 -16.94400 1.000 67.67000  ? 164 GLY A HA3  1 
ATOM   2310 N N    . ASN A 1 167 ? 38.03700 21.74600 -16.05800 1.000 46.83000  ? 165 ASN A N    1 
ATOM   2311 C CA   . ASN A 1 167 ? 36.90400 21.62300 -15.15100 1.000 59.17000  ? 165 ASN A CA   1 
ATOM   2312 C C    . ASN A 1 167 ? 37.33700 21.36000 -13.71200 1.000 54.83000  ? 165 ASN A C    1 
ATOM   2313 O O    . ASN A 1 167 ? 36.53400 20.87500 -12.90700 1.000 53.96000  ? 165 ASN A O    1 
ATOM   2314 C CB   . ASN A 1 167 ? 35.96600 20.50800 -15.62200 1.000 63.17000  ? 165 ASN A CB   1 
ATOM   2315 C CG   . ASN A 1 167 ? 35.45200 20.73400 -17.03400 1.000 67.82000  ? 165 ASN A CG   1 
ATOM   2316 O OD1  . ASN A 1 167 ? 35.15200 21.86300 -17.42500 1.000 63.99000  ? 165 ASN A OD1  1 
ATOM   2317 N ND2  . ASN A 1 167 ? 35.35000 19.65500 -17.80800 1.000 71.92000  ? 165 ASN A ND2  1 
ATOM   2318 H H    . ASN A 1 167 ? 38.40700 20.99300 -16.24700 1.000 56.05000  ? 165 ASN A H    1 
ATOM   2319 H HA   . ASN A 1 167 ? 36.40300 22.45300 -15.16100 1.000 70.86000  ? 165 ASN A HA   1 
ATOM   2320 H HB2  . ASN A 1 167 ? 36.43800 19.66300 -15.61200 1.000 75.65000  ? 165 ASN A HB2  1 
ATOM   2321 H HB3  . ASN A 1 167 ? 35.20200 20.46700 -15.02900 1.000 75.65000  ? 165 ASN A HB3  1 
ATOM   2322 H HD21 . ASN A 1 167 ? 35.57000 18.88300 -17.50000 1.000 86.16000  ? 165 ASN A HD21 1 
ATOM   2323 H HD22 . ASN A 1 167 ? 35.06500 19.73000 -18.61600 1.000 86.16000  ? 165 ASN A HD22 1 
ATOM   2324 N N    . THR A 1 168 ? 38.58700 21.66800 -13.37500 1.000 49.83000  ? 166 THR A N    1 
ATOM   2325 C CA   . THR A 1 168 ? 39.08900 21.43800 -12.02900 1.000 40.39000  ? 166 THR A CA   1 
ATOM   2326 C C    . THR A 1 168 ? 38.64500 22.55500 -11.09100 1.000 37.96000  ? 166 THR A C    1 
ATOM   2327 O O    . THR A 1 168 ? 38.68400 23.73500 -11.44100 1.000 38.48000  ? 166 THR A O    1 
ATOM   2328 C CB   . THR A 1 168 ? 40.61400 21.34000 -12.03800 1.000 47.03000  ? 166 THR A CB   1 
ATOM   2329 O OG1  . THR A 1 168 ? 41.01500 20.14300 -12.71400 1.000 51.59000  ? 166 THR A OG1  1 
ATOM   2330 C CG2  . THR A 1 168 ? 41.15900 21.31200 -10.62200 1.000 39.55000  ? 166 THR A CG2  1 
ATOM   2331 H H    . THR A 1 168 ? 39.16500 22.01300 -13.91000 1.000 59.65000  ? 166 THR A H    1 
ATOM   2332 H HA   . THR A 1 168 ? 38.73100 20.60300 -11.69400 1.000 48.32000  ? 166 THR A HA   1 
ATOM   2333 H HB   . THR A 1 168 ? 40.98500 22.11000 -12.49600 1.000 56.29000  ? 166 THR A HB   1 
ATOM   2334 H HG1  . THR A 1 168 ? 41.85300 20.08400 -12.72200 1.000 61.76000  ? 166 THR A HG1  1 
ATOM   2335 H HG21 . THR A 1 168 ? 42.05900 20.95000 -10.62400 1.000 47.32000  ? 166 THR A HG21 1 
ATOM   2336 H HG22 . THR A 1 168 ? 41.18300 22.20900 -10.25400 1.000 47.32000  ? 166 THR A HG22 1 
ATOM   2337 H HG23 . THR A 1 168 ? 40.59800 20.75400 -10.06100 1.000 47.32000  ? 166 THR A HG23 1 
ATOM   2338 N N    . VAL A 1 169 ? 38.21800 22.16400 -9.89400  1.000 37.10000  ? 167 VAL A N    1 
ATOM   2339 C CA   . VAL A 1 169 ? 37.79300 23.08900 -8.85500  1.000 34.40000  ? 167 VAL A CA   1 
ATOM   2340 C C    . VAL A 1 169 ? 38.57500 22.74700 -7.59300  1.000 38.62000  ? 167 VAL A C    1 
ATOM   2341 O O    . VAL A 1 169 ? 39.05600 21.62600 -7.41500  1.000 40.20000  ? 167 VAL A O    1 
ATOM   2342 C CB   . VAL A 1 169 ? 36.27800 23.02700 -8.58700  1.000 38.33000  ? 167 VAL A CB   1 
ATOM   2343 C CG1  . VAL A 1 169 ? 35.52000 23.69500 -9.71800  1.000 39.93000  ? 167 VAL A CG1  1 
ATOM   2344 C CG2  . VAL A 1 169 ? 35.82400 21.59100 -8.42700  1.000 39.41000  ? 167 VAL A CG2  1 
ATOM   2345 H H    . VAL A 1 169 ? 38.16600 21.33900 -9.65500  1.000 44.37000  ? 167 VAL A H    1 
ATOM   2346 H HA   . VAL A 1 169 ? 38.01800 23.99500 -9.11600  1.000 41.13000  ? 167 VAL A HA   1 
ATOM   2347 H HB   . VAL A 1 169 ? 36.07800 23.50300 -7.76600  1.000 45.85000  ? 167 VAL A HB   1 
ATOM   2348 H HG11 . VAL A 1 169 ? 34.56900 23.64400 -9.53500  1.000 47.77000  ? 167 VAL A HG11 1 
ATOM   2349 H HG12 . VAL A 1 169 ? 35.79600 24.62300 -9.77800  1.000 47.77000  ? 167 VAL A HG12 1 
ATOM   2350 H HG13 . VAL A 1 169 ? 35.72200 23.23600 -10.54800 1.000 47.77000  ? 167 VAL A HG13 1 
ATOM   2351 H HG21 . VAL A 1 169 ? 34.88600 21.58400 -8.18100  1.000 47.15000  ? 167 VAL A HG21 1 
ATOM   2352 H HG22 . VAL A 1 169 ? 35.94800 21.12300 -9.26700  1.000 47.15000  ? 167 VAL A HG22 1 
ATOM   2353 H HG23 . VAL A 1 169 ? 36.35000 21.16800 -7.73100  1.000 47.15000  ? 167 VAL A HG23 1 
ATOM   2354 N N    . ILE A 1 170 ? 38.70600 23.73600 -6.71500  1.000 40.85000  ? 168 ILE A N    1 
ATOM   2355 C CA   . ILE A 1 170 ? 39.49400 23.59900 -5.50000  1.000 33.44000  ? 168 ILE A CA   1 
ATOM   2356 C C    . ILE A 1 170 ? 38.57200 23.77500 -4.30700  1.000 36.90000  ? 168 ILE A C    1 
ATOM   2357 O O    . ILE A 1 170 ? 37.88000 24.79400 -4.19400  1.000 36.30000  ? 168 ILE A O    1 
ATOM   2358 C CB   . ILE A 1 170 ? 40.64300 24.62000 -5.43600  1.000 39.15000  ? 168 ILE A CB   1 
ATOM   2359 C CG1  . ILE A 1 170 ? 41.50600 24.54100 -6.69300  1.000 37.85000  ? 168 ILE A CG1  1 
ATOM   2360 C CG2  . ILE A 1 170 ? 41.46800 24.38200 -4.17700  1.000 38.20000  ? 168 ILE A CG2  1 
ATOM   2361 C CD1  . ILE A 1 170 ? 42.16700 23.20500 -6.90700  1.000 37.76000  ? 168 ILE A CD1  1 
ATOM   2362 H H    . ILE A 1 170 ? 38.34000 24.50900 -6.80400  1.000 48.87000  ? 168 ILE A H    1 
ATOM   2363 H HA   . ILE A 1 170 ? 39.87400 22.70800 -5.45700  1.000 39.98000  ? 168 ILE A HA   1 
ATOM   2364 H HB   . ILE A 1 170 ? 40.25700 25.50800 -5.38400  1.000 46.83000  ? 168 ILE A HB   1 
ATOM   2365 H HG12 . ILE A 1 170 ? 40.95100 24.72400 -7.46700  1.000 45.28000  ? 168 ILE A HG12 1 
ATOM   2366 H HG13 . ILE A 1 170 ? 42.20700 25.20800 -6.62900  1.000 45.28000  ? 168 ILE A HG13 1 
ATOM   2367 H HG21 . ILE A 1 170 ? 42.31700 24.84300 -4.26500  1.000 45.69000  ? 168 ILE A HG21 1 
ATOM   2368 H HG22 . ILE A 1 170 ? 40.98400 24.72600 -3.41000  1.000 45.69000  ? 168 ILE A HG22 1 
ATOM   2369 H HG23 . ILE A 1 170 ? 41.61800 23.43000 -4.07500  1.000 45.69000  ? 168 ILE A HG23 1 
ATOM   2370 H HD11 . ILE A 1 170 ? 42.69000 22.97900 -6.12300  1.000 45.16000  ? 168 ILE A HD11 1 
ATOM   2371 H HD12 . ILE A 1 170 ? 41.48400 22.53400 -7.05500  1.000 45.16000  ? 168 ILE A HD12 1 
ATOM   2372 H HD13 . ILE A 1 170 ? 42.74500 23.26400 -7.68400  1.000 45.16000  ? 168 ILE A HD13 1 
ATOM   2373 N N    . CYS A 1 171 ? 38.59300 22.80000 -3.41100  1.000 31.09000  ? 169 CYS A N    1 
ATOM   2374 C CA   . CYS A 1 171 ? 37.79700 22.79100 -2.18800  1.000 34.82000  ? 169 CYS A CA   1 
ATOM   2375 C C    . CYS A 1 171 ? 38.75300 23.00100 -1.02000  1.000 39.37000  ? 169 CYS A C    1 
ATOM   2376 O O    . CYS A 1 171 ? 39.51800 22.09800 -0.67300  1.000 37.65000  ? 169 CYS A O    1 
ATOM   2377 C CB   . CYS A 1 171 ? 37.03900 21.47000 -2.08500  1.000 37.22000  ? 169 CYS A CB   1 
ATOM   2378 S SG   . CYS A 1 171 ? 36.27000 21.13400 -0.49900  1.000 42.20000  ? 169 CYS A SG   1 
ATOM   2379 H H    . CYS A 1 171 ? 39.08400 22.09800 -3.49300  1.000 37.16000  ? 169 CYS A H    1 
ATOM   2380 H HA   . CYS A 1 171 ? 37.15600 23.51900 -2.20400  1.000 41.63000  ? 169 CYS A HA   1 
ATOM   2381 H HB2  . CYS A 1 171 ? 36.33700 21.46700 -2.75500  1.000 44.52000  ? 169 CYS A HB2  1 
ATOM   2382 H HB3  . CYS A 1 171 ? 37.66000 20.74700 -2.26500  1.000 44.52000  ? 169 CYS A HB3  1 
ATOM   2383 H HG   . CYS A 1 171 ? 35.46900 21.99800 -0.27200  1.000 50.49000  ? 169 CYS A HG   1 
ATOM   2384 N N    . ALA A 1 172 ? 38.74000 24.19700 -0.44400  1.000 33.94000  ? 170 ALA A N    1 
ATOM   2385 C CA   . ALA A 1 172 ? 39.55100 24.45000 0.73700   1.000 35.20000  ? 170 ALA A CA   1 
ATOM   2386 C C    . ALA A 1 172 ? 39.00300 23.67300 1.92300   1.000 33.04000  ? 170 ALA A C    1 
ATOM   2387 O O    . ALA A 1 172 ? 37.79600 23.64400 2.16800   1.000 29.03000  ? 170 ALA A O    1 
ATOM   2388 C CB   . ALA A 1 172 ? 39.57000 25.94300 1.07200   1.000 36.62000  ? 170 ALA A CB   1 
ATOM   2389 H H    . ALA A 1 172 ? 38.27700 24.87000 -0.71300  1.000 40.58000  ? 170 ALA A H    1 
ATOM   2390 H HA   . ALA A 1 172 ? 40.46200 24.16000 0.57400   1.000 42.09000  ? 170 ALA A HA   1 
ATOM   2391 H HB1  . ALA A 1 172 ? 40.00100 26.06700 1.93100   1.000 43.79000  ? 170 ALA A HB1  1 
ATOM   2392 H HB2  . ALA A 1 172 ? 40.06800 26.40900 0.38300   1.000 43.79000  ? 170 ALA A HB2  1 
ATOM   2393 H HB3  . ALA A 1 172 ? 38.65800 26.27200 1.11200   1.000 43.79000  ? 170 ALA A HB3  1 
ATOM   2394 N N    . THR A 1 173 ? 39.90700 23.03800 2.67000   1.000 37.69000  ? 171 THR A N    1 
ATOM   2395 C CA   . THR A 1 173 ? 39.53500 22.18700 3.79200   1.000 36.46000  ? 171 THR A CA   1 
ATOM   2396 C C    . THR A 1 173 ? 40.19300 22.67900 5.07700   1.000 34.69000  ? 171 THR A C    1 
ATOM   2397 O O    . THR A 1 173 ? 41.11900 23.49400 5.06700   1.000 38.38000  ? 171 THR A O    1 
ATOM   2398 C CB   . THR A 1 173 ? 39.93600 20.72000 3.54600   1.000 42.07000  ? 171 THR A CB   1 
ATOM   2399 O OG1  . THR A 1 173 ? 41.36600 20.63300 3.45600   1.000 40.02000  ? 171 THR A OG1  1 
ATOM   2400 C CG2  . THR A 1 173 ? 39.31300 20.16800 2.26700   1.000 38.53000  ? 171 THR A CG2  1 
ATOM   2401 H H    . THR A 1 173 ? 40.75600 23.08700 2.54100   1.000 45.09000  ? 171 THR A H    1 
ATOM   2402 H HA   . THR A 1 173 ? 38.57400 22.22000 3.91500   1.000 43.60000  ? 171 THR A HA   1 
ATOM   2403 H HB   . THR A 1 173 ? 39.63100 20.17800 4.29000   1.000 50.34000  ? 171 THR A HB   1 
ATOM   2404 H HG1  . THR A 1 173 ? 41.59700 19.83700 3.32200   1.000 47.88000  ? 171 THR A HG1  1 
ATOM   2405 H HG21 . THR A 1 173 ? 39.51600 19.22400 2.18100   1.000 46.09000  ? 171 THR A HG21 1 
ATOM   2406 H HG22 . THR A 1 173 ? 38.35000 20.28300 2.29100   1.000 46.09000  ? 171 THR A HG22 1 
ATOM   2407 H HG23 . THR A 1 173 ? 39.66700 20.63900 1.49600   1.000 46.09000  ? 171 THR A HG23 1 
ATOM   2408 N N    . GLN A 1 174 ? 39.70400 22.15100 6.19300   1.000 39.87000  ? 172 GLN A N    1 
ATOM   2409 C CA   . GLN A 1 174 ? 40.27600 22.43100 7.50300   1.000 47.25000  ? 172 GLN A CA   1 
ATOM   2410 C C    . GLN A 1 174 ? 41.65900 21.80800 7.65200   1.000 39.78000  ? 172 GLN A C    1 
ATOM   2411 O O    . GLN A 1 174 ? 42.31900 21.98600 8.67800   1.000 60.59000  ? 172 GLN A O    1 
ATOM   2412 C CB   . GLN A 1 174 ? 39.35200 21.89800 8.60300   1.000 52.83000  ? 172 GLN A CB   1 
ATOM   2413 C CG   . GLN A 1 174 ? 39.33000 20.37800 8.67600   1.000 50.09000  ? 172 GLN A CG   1 
ATOM   2414 C CD   . GLN A 1 174 ? 38.16000 19.84800 9.48100   1.000 52.46000  ? 172 GLN A CD   1 
ATOM   2415 O OE1  . GLN A 1 174 ? 37.01100 20.21600 9.24400   1.000 53.32000  ? 172 GLN A OE1  1 
ATOM   2416 N NE2  . GLN A 1 174 ? 38.44800 18.97500 10.43600  1.000 52.43000  ? 172 GLN A NE2  1 
ATOM   2417 H H    . GLN A 1 174 ? 39.03000 21.61700 6.21700   1.000 47.70000  ? 172 GLN A H    1 
ATOM   2418 H HA   . GLN A 1 174 ? 40.36100 23.39100 7.61600   1.000 56.55000  ? 172 GLN A HA   1 
ATOM   2419 H HB2  . GLN A 1 174 ? 39.65600 22.23500 9.46000   1.000 63.24000  ? 172 GLN A HB2  1 
ATOM   2420 H HB3  . GLN A 1 174 ? 38.44800 22.20200 8.42900   1.000 63.24000  ? 172 GLN A HB3  1 
ATOM   2421 H HG2  . GLN A 1 174 ? 39.26400 20.01800 7.77800   1.000 59.96000  ? 172 GLN A HG2  1 
ATOM   2422 H HG3  . GLN A 1 174 ? 40.14600 20.06900 9.09900   1.000 59.96000  ? 172 GLN A HG3  1 
ATOM   2423 H HE21 . GLN A 1 174 ? 39.26400 18.74000 10.57300  1.000 62.77000  ? 172 GLN A HE21 1 
ATOM   2424 H HE22 . GLN A 1 174 ? 37.81900 18.64500 10.92100  1.000 62.77000  ? 172 GLN A HE22 1 
HETATM 2425 C C01  . AG7 B 2 .   ? 41.06500 31.42700 -9.00600  1.000 33.21000  ? 201 AG7 A C01  1 
HETATM 2426 C C02  . AG7 B 2 .   ? 41.42200 32.37000 -7.87600  1.000 34.45000  ? 201 AG7 A C02  1 
HETATM 2427 O O03  . AG7 B 2 .   ? 40.10200 30.68900 -8.95900  1.000 34.09000  ? 201 AG7 A O03  1 
HETATM 2428 C C04  . AG7 B 2 .   ? 40.44000 32.40100 -6.72600  1.000 35.61000  ? 201 AG7 A C04  1 
HETATM 2429 C C05  . AG7 B 2 .   ? 40.97800 33.31100 -5.61900  1.000 39.20000  ? 201 AG7 A C05  1 
HETATM 2430 C C06  . AG7 B 2 .   ? 42.12900 32.73600 -4.84100  1.000 36.86000  ? 201 AG7 A C06  1 
HETATM 2431 C C07  . AG7 B 2 .   ? 41.96500 31.57800 -4.08100  1.000 41.69000  ? 201 AG7 A C07  1 
HETATM 2432 C C08  . AG7 B 2 .   ? 43.01500 31.03800 -3.35700  1.000 48.67000  ? 201 AG7 A C08  1 
HETATM 2433 C C09  . AG7 B 2 .   ? 44.23900 31.67700 -3.39300  1.000 40.49000  ? 201 AG7 A C09  1 
HETATM 2434 C C10  . AG7 B 2 .   ? 44.44700 32.82500 -4.12500  1.000 40.51000  ? 201 AG7 A C10  1 
HETATM 2435 C C11  . AG7 B 2 .   ? 43.38200 33.34900 -4.84500  1.000 43.89000  ? 201 AG7 A C11  1 
HETATM 2436 N N12  . AG7 B 2 .   ? 38.03000 32.34300 -6.67200  1.000 35.46000  ? 201 AG7 A N12  1 
HETATM 2437 C C13  . AG7 B 2 .   ? 36.66000 32.70400 -7.00100  1.000 42.09000  ? 201 AG7 A C13  1 
HETATM 2438 C C14  . AG7 B 2 .   ? 35.99000 31.54200 -7.73900  1.000 40.63000  ? 201 AG7 A C14  1 
HETATM 2439 C C15  . AG7 B 2 .   ? 36.61400 31.10400 -9.08300  1.000 41.95000  ? 201 AG7 A C15  1 
HETATM 2440 C C16  . AG7 B 2 .   ? 35.76500 30.09900 -9.85500  1.000 45.65000  ? 201 AG7 A C16  1 
HETATM 2441 N N17  . AG7 B 2 .   ? 35.78000 30.46200 -11.15100 1.000 44.56000  ? 201 AG7 A N17  1 
HETATM 2442 O O18  . AG7 B 2 .   ? 35.18300 29.13600 -9.38800  1.000 45.46000  ? 201 AG7 A O18  1 
HETATM 2443 C C19  . AG7 B 2 .   ? 35.86000 33.04500 -5.73000  1.000 43.72000  ? 201 AG7 A C19  1 
HETATM 2444 C C20  . AG7 B 2 .   ? 36.58300 34.09600 -4.91100  1.000 45.64000  ? 201 AG7 A C20  1 
HETATM 2445 C C21  . AG7 B 2 .   ? 36.74300 35.40300 -5.62400  1.000 52.70000  ? 201 AG7 A C21  1 
HETATM 2446 O O22  . AG7 B 2 .   ? 37.84600 36.04500 -5.21400  1.000 57.69000  ? 201 AG7 A O22  1 
HETATM 2447 O O23  . AG7 B 2 .   ? 35.97400 35.81100 -6.46100  1.000 45.56000  ? 201 AG7 A O23  1 
HETATM 2448 C C47  . AG7 B 2 .   ? 39.11000 32.93400 -7.20500  1.000 39.40000  ? 201 AG7 A C47  1 
HETATM 2449 O O48  . AG7 B 2 .   ? 39.04100 33.84200 -8.02000  1.000 40.67000  ? 201 AG7 A O48  1 
HETATM 2450 C C50  . AG7 B 2 .   ? 38.16000 37.37300 -5.68000  1.000 64.69000  ? 201 AG7 A C50  1 
HETATM 2451 C C53  . AG7 B 2 .   ? 38.68000 38.20200 -4.50900  1.000 72.77000  ? 201 AG7 A C53  1 
HETATM 2452 C C57  . AG7 B 2 .   ? 42.02000 31.37500 -10.22600 1.000 39.05000  ? 201 AG7 A C57  1 
HETATM 2453 N N58  . AG7 B 2 .   ? 42.33500 29.95500 -10.21200 1.000 35.33000  ? 201 AG7 A N58  1 
HETATM 2454 C C59  . AG7 B 2 .   ? 43.57800 29.47700 -10.00500 1.000 45.47000  ? 201 AG7 A C59  1 
HETATM 2455 O O60  . AG7 B 2 .   ? 44.56400 30.16700 -9.83800  1.000 45.46000  ? 201 AG7 A O60  1 
HETATM 2456 C C78  . AG7 B 2 .   ? 41.49800 31.94000 -11.52400 1.000 44.17000  ? 201 AG7 A C78  1 
HETATM 2457 C C81  . AG7 B 2 .   ? 40.71100 30.91100 -12.29100 1.000 53.16000  ? 201 AG7 A C81  1 
HETATM 2458 F F1   . AG7 B 2 .   ? 45.25800 31.15200 -2.68900  1.000 47.11000  ? 201 AG7 A F1   1 
HETATM 2459 C C82  . AG7 B 2 .   ? 40.63100 33.19300 -11.27600 1.000 38.19000  ? 201 AG7 A C82  1 
HETATM 2460 C C83  . AG7 B 2 .   ? 36.55400 31.64800 -11.44000 1.000 39.93000  ? 201 AG7 A C83  1 
HETATM 2461 C C84  . AG7 B 2 .   ? 36.63200 32.29800 -10.05300 1.000 40.09000  ? 201 AG7 A C84  1 
HETATM 2462 C C1   . AG7 B 2 .   ? 43.71000 27.99700 -9.98000  1.000 49.68000  ? 201 AG7 A C1   1 
HETATM 2463 C C2   . AG7 B 2 .   ? 44.91800 27.26900 -9.94800  1.000 55.74000  ? 201 AG7 A C2   1 
HETATM 2464 C C3   . AG7 B 2 .   ? 44.50200 25.97800 -9.90200  1.000 56.71000  ? 201 AG7 A C3   1 
HETATM 2465 O O4   . AG7 B 2 .   ? 43.15800 25.95700 -9.88500  1.000 55.04000  ? 201 AG7 A O4   1 
HETATM 2466 N N5   . AG7 B 2 .   ? 42.67100 27.21400 -9.92200  1.000 41.78000  ? 201 AG7 A N5   1 
HETATM 2467 C C4   . AG7 B 2 .   ? 45.21900 24.67600 -9.86000  1.000 59.62000  ? 201 AG7 A C4   1 
HETATM 2468 H H2   . AG7 B 2 .   ? 42.31900 32.18200 -7.55700  1.000 41.19000  ? 201 AG7 A H2   1 
HETATM 2469 H H3   . AG7 B 2 .   ? 41.48300 33.24500 -8.28900  1.000 41.19000  ? 201 AG7 A H3   1 
HETATM 2470 H H27  . AG7 B 2 .   ? 40.33500 31.50100 -6.38000  1.000 42.58000  ? 201 AG7 A H27  1 
HETATM 2471 H H28  . AG7 B 2 .   ? 40.25100 33.52000 -5.01100  1.000 46.89000  ? 201 AG7 A H28  1 
HETATM 2472 H H29  . AG7 B 2 .   ? 41.25300 34.15400 -6.01200  1.000 46.89000  ? 201 AG7 A H29  1 
HETATM 2473 H H30  . AG7 B 2 .   ? 41.14200 31.14600 -4.05600  1.000 49.88000  ? 201 AG7 A H30  1 
HETATM 2474 H H31  . AG7 B 2 .   ? 42.90100 30.26400 -2.85500  1.000 58.26000  ? 201 AG7 A H31  1 
HETATM 2475 H H33  . AG7 B 2 .   ? 45.28000 33.23800 -4.13600  1.000 48.46000  ? 201 AG7 A H33  1 
HETATM 2476 H H34  . AG7 B 2 .   ? 43.51300 34.12400 -5.34300  1.000 52.52000  ? 201 AG7 A H34  1 
HETATM 2477 H H49  . AG7 B 2 .   ? 38.14700 31.70800 -6.10400  1.000 42.41000  ? 201 AG7 A H49  1 
HETATM 2478 H H91  . AG7 B 2 .   ? 36.69400 33.48200 -7.58000  1.000 50.36000  ? 201 AG7 A H91  1 
HETATM 2479 H H35  . AG7 B 2 .   ? 35.05000 31.75000 -7.85900  1.000 48.61000  ? 201 AG7 A H35  1 
HETATM 2480 H H36  . AG7 B 2 .   ? 36.00900 30.76000 -7.16600  1.000 48.61000  ? 201 AG7 A H36  1 
HETATM 2481 H H94  . AG7 B 2 .   ? 37.49500 30.73200 -8.92300  1.000 50.19000  ? 201 AG7 A H94  1 
HETATM 2482 H H39  . AG7 B 2 .   ? 35.35800 30.02100 -11.75700 1.000 53.32000  ? 201 AG7 A H39  1 
HETATM 2483 H H191 . AG7 B 2 .   ? 35.58600 33.79000 -6.27400  1.000 52.32000  ? 201 AG7 A H191 1 
HETATM 2484 H H192 . AG7 B 2 .   ? 34.85700 32.98000 -5.77800  1.000 52.32000  ? 201 AG7 A H192 1 
HETATM 2485 H H41  . AG7 B 2 .   ? 36.10900 34.30500 -4.08900  1.000 54.62000  ? 201 AG7 A H41  1 
HETATM 2486 H H42  . AG7 B 2 .   ? 37.46800 33.80400 -4.63400  1.000 54.62000  ? 201 AG7 A H42  1 
HETATM 2487 H H51  . AG7 B 2 .   ? 37.36500 37.77900 -6.05900  1.000 77.48000  ? 201 AG7 A H51  1 
HETATM 2488 H H52  . AG7 B 2 .   ? 38.82600 37.32200 -6.38300  1.000 77.48000  ? 201 AG7 A H52  1 
HETATM 2489 H H53  . AG7 B 2 .   ? 39.64500 38.14800 -4.43400  1.000 87.17000  ? 201 AG7 A H53  1 
HETATM 2490 H H54  . AG7 B 2 .   ? 38.28900 37.92100 -3.66700  1.000 87.17000  ? 201 AG7 A H54  1 
HETATM 2491 H H56  . AG7 B 2 .   ? 38.44700 39.13300 -4.64900  1.000 87.17000  ? 201 AG7 A H56  1 
HETATM 2492 H H77  . AG7 B 2 .   ? 42.83600 31.84600 -9.99500  1.000 46.71000  ? 201 AG7 A H77  1 
HETATM 2493 H H61  . AG7 B 2 .   ? 41.68700 29.39700 -10.30500 1.000 42.25000  ? 201 AG7 A H61  1 
HETATM 2494 H H79  . AG7 B 2 .   ? 42.25900 32.20400 -12.06400 1.000 52.86000  ? 201 AG7 A H79  1 
HETATM 2495 H H82  . AG7 B 2 .   ? 41.25500 30.13300 -12.48500 1.000 63.65000  ? 201 AG7 A H82  1 
HETATM 2496 H H84  . AG7 B 2 .   ? 40.41400 31.27700 -13.13900 1.000 63.65000  ? 201 AG7 A H84  1 
HETATM 2497 H H85  . AG7 B 2 .   ? 39.91900 30.62000 -11.81500 1.000 63.65000  ? 201 AG7 A H85  1 
HETATM 2498 H H86  . AG7 B 2 .   ? 40.42400 33.66600 -12.09700 1.000 45.68000  ? 201 AG7 A H86  1 
HETATM 2499 H H87  . AG7 B 2 .   ? 41.09400 33.81300 -10.69100 1.000 45.68000  ? 201 AG7 A H87  1 
HETATM 2500 H H88  . AG7 B 2 .   ? 39.79200 32.95800 -10.85000 1.000 45.68000  ? 201 AG7 A H88  1 
HETATM 2501 H H89  . AG7 B 2 .   ? 36.10500 32.20900 -12.09100 1.000 47.77000  ? 201 AG7 A H89  1 
HETATM 2502 H H90  . AG7 B 2 .   ? 37.43100 31.42600 -11.79100 1.000 47.77000  ? 201 AG7 A H90  1 
HETATM 2503 H H92  . AG7 B 2 .   ? 35.91000 32.92400 -9.90200  1.000 47.96000  ? 201 AG7 A H92  1 
HETATM 2504 H H93  . AG7 B 2 .   ? 37.46700 32.78400 -9.96900  1.000 47.96000  ? 201 AG7 A H93  1 
HETATM 2505 H H8   . AG7 B 2 .   ? 45.79000 27.59100 -9.97000  1.000 66.74000  ? 201 AG7 A H8   1 
HETATM 2506 H H5   . AG7 B 2 .   ? 45.03600 24.20100 -9.03400  1.000 71.39000  ? 201 AG7 A H5   1 
HETATM 2507 H H6   . AG7 B 2 .   ? 46.17900 24.80100 -9.92500  1.000 71.39000  ? 201 AG7 A H6   1 
HETATM 2508 H H7   . AG7 B 2 .   ? 44.93100 24.12100 -10.60100 1.000 71.39000  ? 201 AG7 A H7   1 
HETATM 2509 I I    . IOD C 3 .   ? 51.46900 32.12800 1.57200   0.910 51.81000  ? 202 IOD A I    1 
HETATM 2510 I I    . IOD D 3 .   ? 40.36800 25.61500 10.82000  0.780 52.05000  ? 203 IOD A I    1 
HETATM 2511 I I    . IOD E 3 .   ? 23.51400 37.04000 -11.17400 0.710 56.06000  ? 204 IOD A I    1 
HETATM 2512 I I    . IOD F 3 .   ? 16.49000 28.56200 0.00000   0.420 48.23000  ? 205 IOD A I    1 
HETATM 2513 I I    . IOD G 3 .   ? 19.87700 35.11300 -1.80200  0.590 53.06000  ? 206 IOD A I    1 
HETATM 2514 O O    . HOH H 4 .   ? 26.27900 38.21100 21.77900  1.000 43.49000  ? 301 HOH A O    1 
HETATM 2515 O O    . HOH H 4 .   ? 35.18300 12.75900 4.77800   1.000 51.22000  ? 302 HOH A O    1 
HETATM 2516 O O    . HOH H 4 .   ? 27.74900 39.13000 -2.12800  1.000 49.42000  ? 303 HOH A O    1 
HETATM 2517 O O    . HOH H 4 .   ? 43.73800 21.27200 10.45200  1.000 64.51000  ? 304 HOH A O    1 
HETATM 2518 O O    . HOH H 4 .   ? 41.446   18.067   -11.479   1.000 50.07000  ? 305 HOH A O    1 
HETATM 2519 O O    . HOH H 4 .   ? 38.09100 38.65700 3.03700   1.000 42.27000  ? 306 HOH A O    1 
HETATM 2520 O O    . HOH H 4 .   ? 30.37500 38.61700 -5.31500  1.000 48.44000  ? 307 HOH A O    1 
HETATM 2521 O O    . HOH H 4 .   ? 20.66400 32.18000 -12.18900 1.000 49.90000  ? 308 HOH A O    1 
HETATM 2522 O O    . HOH H 4 .   ? 43.02600 26.34300 2.95900   1.000 39.77000  ? 309 HOH A O    1 
HETATM 2523 O O    . HOH H 4 .   ? 43.66100 24.09300 5.19600   1.000 40.59000  ? 310 HOH A O    1 
HETATM 2524 O O    . HOH H 4 .   ? 34.35900 25.95200 -13.26900 1.000 48.64000  ? 311 HOH A O    1 
HETATM 2525 O O    . HOH H 4 .   ? 49.03700 24.47900 -7.88800  1.000 37.16000  ? 312 HOH A O    1 
HETATM 2526 O O    . HOH H 4 .   ? 27.08000 32.72100 -6.59500  1.000 39.84000  ? 313 HOH A O    1 
HETATM 2527 O O    . HOH H 4 .   ? 48.155   15.135   0.763     1.000 40.78000  ? 314 HOH A O    1 
HETATM 2528 O O    . HOH H 4 .   ? 34.56500 36.90800 -3.86600  1.000 45.39000  ? 315 HOH A O    1 
HETATM 2529 O O    . HOH H 4 .   ? 37.00200 24.55400 -13.43200 1.000 44.87000  ? 316 HOH A O    1 
HETATM 2530 O O    . HOH H 4 .   ? 38.84800 14.11500 -9.62100  1.000 39.13000  ? 317 HOH A O    1 
HETATM 2531 O O    . HOH H 4 .   ? 45.35700 12.53000 -1.90500  1.000 44.40000  ? 318 HOH A O    1 
HETATM 2532 O O    . HOH H 4 .   ? 17.52500 31.09600 -3.19300  1.000 47.21000  ? 319 HOH A O    1 
HETATM 2533 O O    . HOH H 4 .   ? 36.97000 36.65000 19.22600  1.000 50.66000  ? 320 HOH A O    1 
HETATM 2534 O O    . HOH H 4 .   ? 28.01200 36.03000 -4.83600  1.000 42.52000  ? 321 HOH A O    1 
HETATM 2535 O O    . HOH H 4 .   ? 47.29000 29.50700 -10.04400 1.000 47.78000  ? 322 HOH A O    1 
HETATM 2536 O O    . HOH H 4 .   ? 36.48300 38.00600 16.05100  1.000 39.62000  ? 323 HOH A O    1 
HETATM 2537 O O    . HOH H 4 .   ? 39.42700 45.56700 6.84700   1.000 45.96000  ? 324 HOH A O    1 
HETATM 2538 O O    . HOH H 4 .   ? 35.08900 41.76000 10.10900  1.000 46.66000  ? 325 HOH A O    1 
HETATM 2539 O O    . HOH H 4 .   ? 27.22900 36.88100 -2.74200  1.000 41.63000  ? 326 HOH A O    1 
HETATM 2540 O O    . HOH H 4 .   ? 37.15700 20.74200 5.74100   1.000 39.54000  ? 327 HOH A O    1 
HETATM 2541 O O    . HOH H 4 .   ? 39.98000 32.66300 17.57200  1.000 44.79000  ? 328 HOH A O    1 
HETATM 2542 O O    . HOH H 4 .   ? 26.08300 40.92500 22.59400  1.000 57.75000  ? 329 HOH A O    1 
HETATM 2543 O O    . HOH H 4 .   ? 28.97700 22.62100 16.20400  1.000 52.33000  ? 330 HOH A O    1 
HETATM 2544 O O    . HOH H 4 .   ? 44.822   32.338   6.029     1.000 48.58000  ? 331 HOH A O    1 
HETATM 2545 O O    . HOH H 4 .   ? 25.17700 24.85600 18.87100  1.000 29.43000  ? 332 HOH A O    1 
HETATM 2546 O O    . HOH H 4 .   ? 42.85700 41.89800 6.13600   1.000 40.78000  ? 333 HOH A O    1 
HETATM 2547 O O    . HOH H 4 .   ? 18.72200 23.67700 18.14100  1.000 59.41000  ? 334 HOH A O    1 
HETATM 2548 O O    . HOH H 4 .   ? 29.18400 46.17400 10.06900  1.000 41.74000  ? 335 HOH A O    1 
HETATM 2549 O O    . HOH H 4 .   ? 18.99100 21.07100 6.91100   1.000 60.18000  ? 336 HOH A O    1 
HETATM 2550 O O    . HOH H 4 .   ? 18.55800 20.27400 9.65200   1.000 52.12000  ? 337 HOH A O    1 
HETATM 2551 O O    . HOH H 4 .   ? 26.53000 18.36300 -12.53000 1.000 47.67000  ? 338 HOH A O    1 
HETATM 2552 O O    . HOH H 4 .   ? 28.78100 19.16000 -12.96100 1.000 47.33000  ? 339 HOH A O    1 
HETATM 2553 O O    . HOH H 4 .   ? 25.17000 14.61300 -1.96100  1.000 42.73000  ? 340 HOH A O    1 
HETATM 2554 O O    . HOH H 4 .   ? 15.127   25.926   1.249     1.000 49.28000  ? 341 HOH A O    1 
HETATM 2555 O O    . HOH H 4 .   ? 48.23900 27.02300 -10.30200 1.000 49.47000  ? 342 HOH A O    1 
HETATM 2556 O O    . HOH H 4 .   ? 22.61100 16.72500 8.54100   1.000 53.65000  ? 343 HOH A O    1 
HETATM 2557 O O    . HOH H 4 .   ? 47.038   17.414   2.448     1.000 44.97000  ? 344 HOH A O    1 
HETATM 2558 O O    . HOH H 4 .   ? 20.04400 18.95100 -4.75700  1.000 56.90000  ? 345 HOH A O    1 
HETATM 2559 O O    . HOH H 4 .   ? 20.98600 17.66200 6.90000   1.000 61.59000  ? 346 HOH A O    1 
HETATM 2560 O O    . HOH H 4 .   ? 47.116   16.314   4.434     1.000 57.70000  ? 347 HOH A O    1 
HETATM 2561 O O    . HOH H 4 .   ? 32.52000 42.61700 1.22400   1.000 45.22000  ? 348 HOH A O    1 
HETATM 2562 O O    . HOH H 4 .   ? 34.32800 44.01000 2.24600   1.000 61.40000  ? 349 HOH A O    1 
HETATM 2563 O O    . HOH H 4 .   ? 20.05600 25.25700 19.30400  1.000 45.07000  ? 350 HOH A O    1 
HETATM 2564 O O    . HOH H 4 .   ? 17.10100 21.67500 19.47900  1.000 64.06000  ? 351 HOH A O    1 
HETATM 2565 O O    . HOH H 4 .   ? 21.41600 17.88000 -2.77700  1.000 52.75000  ? 352 HOH A O    1 
# 
