data_9D7Y
# 
_entry.id   9D7Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9D7Y         pdb_00009d7y 10.2210/pdb9d7y/pdb 
WWPDB D_1000287490 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-06 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9D7Y 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ashley.buckle@monash.edu 
_pdbx_contact_author.name_first         Ashley 
_pdbx_contact_author.name_last          Buckle 
_pdbx_contact_author.name_mi            M 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2943-9044 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Buckle, A.M.' 1 0000-0003-2943-9044 
'McGowan, S.'  2 0000-0001-6863-1106 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.03.18.585568 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Stander, S.H.D.' 1  ? 
primary 'Reboul, C.F.'    2  ? 
primary 'Le, S.N.'        3  ? 
primary 'Williams, D.E.'  4  ? 
primary 'Chandler, P.G.'  5  ? 
primary 'Costa, M.G.S.'   6  ? 
primary 'Hoke, D.E.'      7  ? 
primary 'Jimma, J.D.T.'   8  ? 
primary 'Fodor, J.'       9  ? 
primary 'Fenalti, G.'     10 ? 
primary 'Mannering, S.I.' 11 ? 
primary 'Porebski, B.T.'  12 ? 
primary 'Schofield, P.'   13 ? 
primary 'Christ, D.'      14 ? 
primary 'Buckle, M.'      15 ? 
primary 'McGowan, S.'     16 ? 
primary 'Elmlund, D.'     17 ? 
primary 'Rand, K.D.'      18 ? 
primary 'Buckle, A.M.'    19 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'scFv corresponding to human autoantibody b96.11' 27972.594 3   ? ? ? ? 
2 non-polymer syn 'SULFATE ION'                                     96.063    4   ? ? ? ? 
3 water       nat water                                             18.015    157 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;DEVQLVESGGGLVQPGRSLRLSCSASGFTFGDYAMSWFRLAPGKGLEWVGLIKSRAIDGTPQYAASVKGRFTISRDDSNS
IAYLQMNSLTTEDTAIYYCARDFYDFWNEFSHRTFDFWGQGTLVTVSSSGGGGSGGGGSGGGGSGGGGQSALTQPASASG
SPGQSVTITCTGSSSDVGGYKYVSWYQHHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNMASLTVSGLQAEDEADYYCSS
YAGSYNFYVFGNGTKVTVLGHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;DEVQLVESGGGLVQPGRSLRLSCSASGFTFGDYAMSWFRLAPGKGLEWVGLIKSRAIDGTPQYAASVKGRFTISRDDSNS
IAYLQMNSLTTEDTAIYYCARDFYDFWNEFSHRTFDFWGQGTLVTVSSSGGGGSGGGGSGGGGSGGGGQSALTQPASASG
SPGQSVTITCTGSSSDVGGYKYVSWYQHHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNMASLTVSGLQAEDEADYYCSS
YAGSYNFYVFGNGTKVTVLGHHHHH
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   GLU n 
1 3   VAL n 
1 4   GLN n 
1 5   LEU n 
1 6   VAL n 
1 7   GLU n 
1 8   SER n 
1 9   GLY n 
1 10  GLY n 
1 11  GLY n 
1 12  LEU n 
1 13  VAL n 
1 14  GLN n 
1 15  PRO n 
1 16  GLY n 
1 17  ARG n 
1 18  SER n 
1 19  LEU n 
1 20  ARG n 
1 21  LEU n 
1 22  SER n 
1 23  CYS n 
1 24  SER n 
1 25  ALA n 
1 26  SER n 
1 27  GLY n 
1 28  PHE n 
1 29  THR n 
1 30  PHE n 
1 31  GLY n 
1 32  ASP n 
1 33  TYR n 
1 34  ALA n 
1 35  MET n 
1 36  SER n 
1 37  TRP n 
1 38  PHE n 
1 39  ARG n 
1 40  LEU n 
1 41  ALA n 
1 42  PRO n 
1 43  GLY n 
1 44  LYS n 
1 45  GLY n 
1 46  LEU n 
1 47  GLU n 
1 48  TRP n 
1 49  VAL n 
1 50  GLY n 
1 51  LEU n 
1 52  ILE n 
1 53  LYS n 
1 54  SER n 
1 55  ARG n 
1 56  ALA n 
1 57  ILE n 
1 58  ASP n 
1 59  GLY n 
1 60  THR n 
1 61  PRO n 
1 62  GLN n 
1 63  TYR n 
1 64  ALA n 
1 65  ALA n 
1 66  SER n 
1 67  VAL n 
1 68  LYS n 
1 69  GLY n 
1 70  ARG n 
1 71  PHE n 
1 72  THR n 
1 73  ILE n 
1 74  SER n 
1 75  ARG n 
1 76  ASP n 
1 77  ASP n 
1 78  SER n 
1 79  ASN n 
1 80  SER n 
1 81  ILE n 
1 82  ALA n 
1 83  TYR n 
1 84  LEU n 
1 85  GLN n 
1 86  MET n 
1 87  ASN n 
1 88  SER n 
1 89  LEU n 
1 90  THR n 
1 91  THR n 
1 92  GLU n 
1 93  ASP n 
1 94  THR n 
1 95  ALA n 
1 96  ILE n 
1 97  TYR n 
1 98  TYR n 
1 99  CYS n 
1 100 ALA n 
1 101 ARG n 
1 102 ASP n 
1 103 PHE n 
1 104 TYR n 
1 105 ASP n 
1 106 PHE n 
1 107 TRP n 
1 108 ASN n 
1 109 GLU n 
1 110 PHE n 
1 111 SER n 
1 112 HIS n 
1 113 ARG n 
1 114 THR n 
1 115 PHE n 
1 116 ASP n 
1 117 PHE n 
1 118 TRP n 
1 119 GLY n 
1 120 GLN n 
1 121 GLY n 
1 122 THR n 
1 123 LEU n 
1 124 VAL n 
1 125 THR n 
1 126 VAL n 
1 127 SER n 
1 128 SER n 
1 129 SER n 
1 130 GLY n 
1 131 GLY n 
1 132 GLY n 
1 133 GLY n 
1 134 SER n 
1 135 GLY n 
1 136 GLY n 
1 137 GLY n 
1 138 GLY n 
1 139 SER n 
1 140 GLY n 
1 141 GLY n 
1 142 GLY n 
1 143 GLY n 
1 144 SER n 
1 145 GLY n 
1 146 GLY n 
1 147 GLY n 
1 148 GLY n 
1 149 GLN n 
1 150 SER n 
1 151 ALA n 
1 152 LEU n 
1 153 THR n 
1 154 GLN n 
1 155 PRO n 
1 156 ALA n 
1 157 SER n 
1 158 ALA n 
1 159 SER n 
1 160 GLY n 
1 161 SER n 
1 162 PRO n 
1 163 GLY n 
1 164 GLN n 
1 165 SER n 
1 166 VAL n 
1 167 THR n 
1 168 ILE n 
1 169 THR n 
1 170 CYS n 
1 171 THR n 
1 172 GLY n 
1 173 SER n 
1 174 SER n 
1 175 SER n 
1 176 ASP n 
1 177 VAL n 
1 178 GLY n 
1 179 GLY n 
1 180 TYR n 
1 181 LYS n 
1 182 TYR n 
1 183 VAL n 
1 184 SER n 
1 185 TRP n 
1 186 TYR n 
1 187 GLN n 
1 188 HIS n 
1 189 HIS n 
1 190 PRO n 
1 191 GLY n 
1 192 LYS n 
1 193 ALA n 
1 194 PRO n 
1 195 LYS n 
1 196 LEU n 
1 197 MET n 
1 198 ILE n 
1 199 TYR n 
1 200 GLU n 
1 201 VAL n 
1 202 SER n 
1 203 LYS n 
1 204 ARG n 
1 205 PRO n 
1 206 SER n 
1 207 GLY n 
1 208 VAL n 
1 209 PRO n 
1 210 ASP n 
1 211 ARG n 
1 212 PHE n 
1 213 SER n 
1 214 GLY n 
1 215 SER n 
1 216 LYS n 
1 217 SER n 
1 218 GLY n 
1 219 ASN n 
1 220 MET n 
1 221 ALA n 
1 222 SER n 
1 223 LEU n 
1 224 THR n 
1 225 VAL n 
1 226 SER n 
1 227 GLY n 
1 228 LEU n 
1 229 GLN n 
1 230 ALA n 
1 231 GLU n 
1 232 ASP n 
1 233 GLU n 
1 234 ALA n 
1 235 ASP n 
1 236 TYR n 
1 237 TYR n 
1 238 CYS n 
1 239 SER n 
1 240 SER n 
1 241 TYR n 
1 242 ALA n 
1 243 GLY n 
1 244 SER n 
1 245 TYR n 
1 246 ASN n 
1 247 PHE n 
1 248 TYR n 
1 249 VAL n 
1 250 PHE n 
1 251 GLY n 
1 252 ASN n 
1 253 GLY n 
1 254 THR n 
1 255 LYS n 
1 256 VAL n 
1 257 THR n 
1 258 VAL n 
1 259 LEU n 
1 260 GLY n 
1 261 HIS n 
1 262 HIS n 
1 263 HIS n 
1 264 HIS n 
1 265 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   265 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               human 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                Kidney 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            expi293 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       'pcDNA3.1(-)' 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   0   0   ASP ASP A . n 
A 1 2   GLU 2   1   1   GLU GLU A . n 
A 1 3   VAL 3   2   2   VAL VAL A . n 
A 1 4   GLN 4   3   3   GLN GLN A . n 
A 1 5   LEU 5   4   4   LEU LEU A . n 
A 1 6   VAL 6   5   5   VAL VAL A . n 
A 1 7   GLU 7   6   6   GLU GLU A . n 
A 1 8   SER 8   7   7   SER SER A . n 
A 1 9   GLY 9   8   8   GLY GLY A . n 
A 1 10  GLY 10  9   9   GLY GLY A . n 
A 1 11  GLY 11  10  10  GLY GLY A . n 
A 1 12  LEU 12  11  11  LEU LEU A . n 
A 1 13  VAL 13  12  12  VAL VAL A . n 
A 1 14  GLN 14  13  13  GLN GLN A . n 
A 1 15  PRO 15  14  14  PRO PRO A . n 
A 1 16  GLY 16  15  15  GLY GLY A . n 
A 1 17  ARG 17  16  16  ARG ARG A . n 
A 1 18  SER 18  17  17  SER SER A . n 
A 1 19  LEU 19  18  18  LEU LEU A . n 
A 1 20  ARG 20  19  19  ARG ARG A . n 
A 1 21  LEU 21  20  20  LEU LEU A . n 
A 1 22  SER 22  21  21  SER SER A . n 
A 1 23  CYS 23  22  22  CYS CYS A . n 
A 1 24  SER 24  23  23  SER SER A . n 
A 1 25  ALA 25  24  24  ALA ALA A . n 
A 1 26  SER 26  25  25  SER SER A . n 
A 1 27  GLY 27  26  26  GLY GLY A . n 
A 1 28  PHE 28  27  27  PHE PHE A . n 
A 1 29  THR 29  28  28  THR THR A . n 
A 1 30  PHE 30  29  29  PHE PHE A . n 
A 1 31  GLY 31  30  30  GLY GLY A . n 
A 1 32  ASP 32  31  31  ASP ASP A . n 
A 1 33  TYR 33  32  32  TYR TYR A . n 
A 1 34  ALA 34  33  33  ALA ALA A . n 
A 1 35  MET 35  34  34  MET MET A . n 
A 1 36  SER 36  35  35  SER SER A . n 
A 1 37  TRP 37  36  36  TRP TRP A . n 
A 1 38  PHE 38  37  37  PHE PHE A . n 
A 1 39  ARG 39  38  38  ARG ARG A . n 
A 1 40  LEU 40  39  39  LEU LEU A . n 
A 1 41  ALA 41  40  40  ALA ALA A . n 
A 1 42  PRO 42  41  41  PRO PRO A . n 
A 1 43  GLY 43  42  42  GLY GLY A . n 
A 1 44  LYS 44  43  43  LYS LYS A . n 
A 1 45  GLY 45  44  44  GLY GLY A . n 
A 1 46  LEU 46  45  45  LEU LEU A . n 
A 1 47  GLU 47  46  46  GLU GLU A . n 
A 1 48  TRP 48  47  47  TRP TRP A . n 
A 1 49  VAL 49  48  48  VAL VAL A . n 
A 1 50  GLY 50  49  49  GLY GLY A . n 
A 1 51  LEU 51  50  50  LEU LEU A . n 
A 1 52  ILE 52  51  51  ILE ILE A . n 
A 1 53  LYS 53  52  52  LYS LYS A . n 
A 1 54  SER 54  53  53  SER SER A . n 
A 1 55  ARG 55  54  54  ARG ARG A . n 
A 1 56  ALA 56  55  55  ALA ALA A . n 
A 1 57  ILE 57  56  56  ILE ILE A . n 
A 1 58  ASP 58  57  57  ASP ASP A . n 
A 1 59  GLY 59  58  58  GLY GLY A . n 
A 1 60  THR 60  59  59  THR THR A . n 
A 1 61  PRO 61  60  60  PRO PRO A . n 
A 1 62  GLN 62  61  61  GLN GLN A . n 
A 1 63  TYR 63  62  62  TYR TYR A . n 
A 1 64  ALA 64  63  63  ALA ALA A . n 
A 1 65  ALA 65  64  64  ALA ALA A . n 
A 1 66  SER 66  65  65  SER SER A . n 
A 1 67  VAL 67  66  66  VAL VAL A . n 
A 1 68  LYS 68  67  67  LYS LYS A . n 
A 1 69  GLY 69  68  68  GLY GLY A . n 
A 1 70  ARG 70  69  69  ARG ARG A . n 
A 1 71  PHE 71  70  70  PHE PHE A . n 
A 1 72  THR 72  71  71  THR THR A . n 
A 1 73  ILE 73  72  72  ILE ILE A . n 
A 1 74  SER 74  73  73  SER SER A . n 
A 1 75  ARG 75  74  74  ARG ARG A . n 
A 1 76  ASP 76  75  75  ASP ASP A . n 
A 1 77  ASP 77  76  76  ASP ASP A . n 
A 1 78  SER 78  77  77  SER SER A . n 
A 1 79  ASN 79  78  78  ASN ASN A . n 
A 1 80  SER 80  79  79  SER SER A . n 
A 1 81  ILE 81  80  80  ILE ILE A . n 
A 1 82  ALA 82  81  81  ALA ALA A . n 
A 1 83  TYR 83  82  82  TYR TYR A . n 
A 1 84  LEU 84  83  83  LEU LEU A . n 
A 1 85  GLN 85  84  84  GLN GLN A . n 
A 1 86  MET 86  85  85  MET MET A . n 
A 1 87  ASN 87  86  86  ASN ASN A . n 
A 1 88  SER 88  87  87  SER SER A . n 
A 1 89  LEU 89  88  88  LEU LEU A . n 
A 1 90  THR 90  89  89  THR THR A . n 
A 1 91  THR 91  90  90  THR THR A . n 
A 1 92  GLU 92  91  91  GLU GLU A . n 
A 1 93  ASP 93  92  92  ASP ASP A . n 
A 1 94  THR 94  93  93  THR THR A . n 
A 1 95  ALA 95  94  94  ALA ALA A . n 
A 1 96  ILE 96  95  95  ILE ILE A . n 
A 1 97  TYR 97  96  96  TYR TYR A . n 
A 1 98  TYR 98  97  97  TYR TYR A . n 
A 1 99  CYS 99  98  98  CYS CYS A . n 
A 1 100 ALA 100 99  99  ALA ALA A . n 
A 1 101 ARG 101 100 100 ARG ARG A . n 
A 1 102 ASP 102 101 101 ASP ASP A . n 
A 1 103 PHE 103 102 102 PHE PHE A . n 
A 1 104 TYR 104 103 103 TYR TYR A . n 
A 1 105 ASP 105 104 104 ASP ASP A . n 
A 1 106 PHE 106 105 105 PHE PHE A . n 
A 1 107 TRP 107 106 106 TRP TRP A . n 
A 1 108 ASN 108 107 107 ASN ASN A . n 
A 1 109 GLU 109 108 108 GLU GLU A . n 
A 1 110 PHE 110 109 109 PHE PHE A . n 
A 1 111 SER 111 110 110 SER SER A . n 
A 1 112 HIS 112 111 111 HIS HIS A . n 
A 1 113 ARG 113 112 112 ARG ARG A . n 
A 1 114 THR 114 113 113 THR THR A . n 
A 1 115 PHE 115 114 114 PHE PHE A . n 
A 1 116 ASP 116 115 115 ASP ASP A . n 
A 1 117 PHE 117 116 116 PHE PHE A . n 
A 1 118 TRP 118 117 117 TRP TRP A . n 
A 1 119 GLY 119 118 118 GLY GLY A . n 
A 1 120 GLN 120 119 119 GLN GLN A . n 
A 1 121 GLY 121 120 120 GLY GLY A . n 
A 1 122 THR 122 121 121 THR THR A . n 
A 1 123 LEU 123 122 122 LEU LEU A . n 
A 1 124 VAL 124 123 123 VAL VAL A . n 
A 1 125 THR 125 124 124 THR THR A . n 
A 1 126 VAL 126 125 125 VAL VAL A . n 
A 1 127 SER 127 126 126 SER SER A . n 
A 1 128 SER 128 127 127 SER SER A . n 
A 1 129 SER 129 128 ?   ?   ?   A . n 
A 1 130 GLY 130 129 ?   ?   ?   A . n 
A 1 131 GLY 131 130 ?   ?   ?   A . n 
A 1 132 GLY 132 131 ?   ?   ?   A . n 
A 1 133 GLY 133 132 ?   ?   ?   A . n 
A 1 134 SER 134 133 ?   ?   ?   A . n 
A 1 135 GLY 135 134 ?   ?   ?   A . n 
A 1 136 GLY 136 135 ?   ?   ?   A . n 
A 1 137 GLY 137 136 ?   ?   ?   A . n 
A 1 138 GLY 138 137 ?   ?   ?   A . n 
A 1 139 SER 139 138 ?   ?   ?   A . n 
A 1 140 GLY 140 139 ?   ?   ?   A . n 
A 1 141 GLY 141 140 ?   ?   ?   A . n 
A 1 142 GLY 142 141 ?   ?   ?   A . n 
A 1 143 GLY 143 142 ?   ?   ?   A . n 
A 1 144 SER 144 143 ?   ?   ?   A . n 
A 1 145 GLY 145 144 ?   ?   ?   A . n 
A 1 146 GLY 146 145 ?   ?   ?   A . n 
A 1 147 GLY 147 146 ?   ?   ?   A . n 
A 1 148 GLY 148 147 ?   ?   ?   A . n 
A 1 149 GLN 149 148 ?   ?   ?   A . n 
A 1 150 SER 150 149 ?   ?   ?   A . n 
A 1 151 ALA 151 150 150 ALA ALA A . n 
A 1 152 LEU 152 151 151 LEU LEU A . n 
A 1 153 THR 153 152 152 THR THR A . n 
A 1 154 GLN 154 153 153 GLN GLN A . n 
A 1 155 PRO 155 154 154 PRO PRO A . n 
A 1 156 ALA 156 155 155 ALA ALA A . n 
A 1 157 SER 157 156 156 SER SER A . n 
A 1 158 ALA 158 157 157 ALA ALA A . n 
A 1 159 SER 159 158 158 SER SER A . n 
A 1 160 GLY 160 159 159 GLY GLY A . n 
A 1 161 SER 161 160 160 SER SER A . n 
A 1 162 PRO 162 161 161 PRO PRO A . n 
A 1 163 GLY 163 162 162 GLY GLY A . n 
A 1 164 GLN 164 163 163 GLN GLN A . n 
A 1 165 SER 165 164 164 SER SER A . n 
A 1 166 VAL 166 165 165 VAL VAL A . n 
A 1 167 THR 167 166 166 THR THR A . n 
A 1 168 ILE 168 167 167 ILE ILE A . n 
A 1 169 THR 169 168 168 THR THR A . n 
A 1 170 CYS 170 169 169 CYS CYS A . n 
A 1 171 THR 171 170 170 THR THR A . n 
A 1 172 GLY 172 171 171 GLY GLY A . n 
A 1 173 SER 173 172 172 SER SER A . n 
A 1 174 SER 174 173 173 SER SER A . n 
A 1 175 SER 175 174 174 SER SER A . n 
A 1 176 ASP 176 175 175 ASP ASP A . n 
A 1 177 VAL 177 176 176 VAL VAL A . n 
A 1 178 GLY 178 177 177 GLY GLY A . n 
A 1 179 GLY 179 178 178 GLY GLY A . n 
A 1 180 TYR 180 179 179 TYR TYR A . n 
A 1 181 LYS 181 180 180 LYS LYS A . n 
A 1 182 TYR 182 181 181 TYR TYR A . n 
A 1 183 VAL 183 182 182 VAL VAL A . n 
A 1 184 SER 184 183 183 SER SER A . n 
A 1 185 TRP 185 184 184 TRP TRP A . n 
A 1 186 TYR 186 185 185 TYR TYR A . n 
A 1 187 GLN 187 186 186 GLN GLN A . n 
A 1 188 HIS 188 187 187 HIS HIS A . n 
A 1 189 HIS 189 188 188 HIS HIS A . n 
A 1 190 PRO 190 189 189 PRO PRO A . n 
A 1 191 GLY 191 190 190 GLY GLY A . n 
A 1 192 LYS 192 191 191 LYS LYS A . n 
A 1 193 ALA 193 192 192 ALA ALA A . n 
A 1 194 PRO 194 193 193 PRO PRO A . n 
A 1 195 LYS 195 194 194 LYS LYS A . n 
A 1 196 LEU 196 195 195 LEU LEU A . n 
A 1 197 MET 197 196 196 MET MET A . n 
A 1 198 ILE 198 197 197 ILE ILE A . n 
A 1 199 TYR 199 198 198 TYR TYR A . n 
A 1 200 GLU 200 199 199 GLU GLU A . n 
A 1 201 VAL 201 200 200 VAL VAL A . n 
A 1 202 SER 202 201 201 SER SER A . n 
A 1 203 LYS 203 202 202 LYS LYS A . n 
A 1 204 ARG 204 203 203 ARG ARG A . n 
A 1 205 PRO 205 204 204 PRO PRO A . n 
A 1 206 SER 206 205 205 SER SER A . n 
A 1 207 GLY 207 206 206 GLY GLY A . n 
A 1 208 VAL 208 207 207 VAL VAL A . n 
A 1 209 PRO 209 208 208 PRO PRO A . n 
A 1 210 ASP 210 209 209 ASP ASP A . n 
A 1 211 ARG 211 210 210 ARG ARG A . n 
A 1 212 PHE 212 211 211 PHE PHE A . n 
A 1 213 SER 213 212 212 SER SER A . n 
A 1 214 GLY 214 213 213 GLY GLY A . n 
A 1 215 SER 215 214 214 SER SER A . n 
A 1 216 LYS 216 215 215 LYS LYS A . n 
A 1 217 SER 217 216 216 SER SER A . n 
A 1 218 GLY 218 217 217 GLY GLY A . n 
A 1 219 ASN 219 218 218 ASN ASN A . n 
A 1 220 MET 220 219 219 MET MET A . n 
A 1 221 ALA 221 220 220 ALA ALA A . n 
A 1 222 SER 222 221 221 SER SER A . n 
A 1 223 LEU 223 222 222 LEU LEU A . n 
A 1 224 THR 224 223 223 THR THR A . n 
A 1 225 VAL 225 224 224 VAL VAL A . n 
A 1 226 SER 226 225 225 SER SER A . n 
A 1 227 GLY 227 226 226 GLY GLY A . n 
A 1 228 LEU 228 227 227 LEU LEU A . n 
A 1 229 GLN 229 228 228 GLN GLN A . n 
A 1 230 ALA 230 229 229 ALA ALA A . n 
A 1 231 GLU 231 230 230 GLU GLU A . n 
A 1 232 ASP 232 231 231 ASP ASP A . n 
A 1 233 GLU 233 232 232 GLU GLU A . n 
A 1 234 ALA 234 233 233 ALA ALA A . n 
A 1 235 ASP 235 234 234 ASP ASP A . n 
A 1 236 TYR 236 235 235 TYR TYR A . n 
A 1 237 TYR 237 236 236 TYR TYR A . n 
A 1 238 CYS 238 237 237 CYS CYS A . n 
A 1 239 SER 239 238 238 SER SER A . n 
A 1 240 SER 240 239 239 SER SER A . n 
A 1 241 TYR 241 240 240 TYR TYR A . n 
A 1 242 ALA 242 241 241 ALA ALA A . n 
A 1 243 GLY 243 242 242 GLY GLY A . n 
A 1 244 SER 244 243 243 SER SER A . n 
A 1 245 TYR 245 244 244 TYR TYR A . n 
A 1 246 ASN 246 245 245 ASN ASN A . n 
A 1 247 PHE 247 246 246 PHE PHE A . n 
A 1 248 TYR 248 247 247 TYR TYR A . n 
A 1 249 VAL 249 248 248 VAL VAL A . n 
A 1 250 PHE 250 249 249 PHE PHE A . n 
A 1 251 GLY 251 250 250 GLY GLY A . n 
A 1 252 ASN 252 251 251 ASN ASN A . n 
A 1 253 GLY 253 252 252 GLY GLY A . n 
A 1 254 THR 254 253 253 THR THR A . n 
A 1 255 LYS 255 254 254 LYS LYS A . n 
A 1 256 VAL 256 255 255 VAL VAL A . n 
A 1 257 THR 257 256 256 THR THR A . n 
A 1 258 VAL 258 257 257 VAL VAL A . n 
A 1 259 LEU 259 258 ?   ?   ?   A . n 
A 1 260 GLY 260 259 ?   ?   ?   A . n 
A 1 261 HIS 261 260 ?   ?   ?   A . n 
A 1 262 HIS 262 261 ?   ?   ?   A . n 
A 1 263 HIS 263 262 ?   ?   ?   A . n 
A 1 264 HIS 264 263 ?   ?   ?   A . n 
A 1 265 HIS 265 264 ?   ?   ?   A . n 
B 1 1   ASP 1   0   ?   ?   ?   B . n 
B 1 2   GLU 2   1   1   GLU GLU B . n 
B 1 3   VAL 3   2   2   VAL VAL B . n 
B 1 4   GLN 4   3   3   GLN GLN B . n 
B 1 5   LEU 5   4   4   LEU LEU B . n 
B 1 6   VAL 6   5   5   VAL VAL B . n 
B 1 7   GLU 7   6   6   GLU GLU B . n 
B 1 8   SER 8   7   7   SER SER B . n 
B 1 9   GLY 9   8   8   GLY GLY B . n 
B 1 10  GLY 10  9   9   GLY GLY B . n 
B 1 11  GLY 11  10  10  GLY GLY B . n 
B 1 12  LEU 12  11  11  LEU LEU B . n 
B 1 13  VAL 13  12  12  VAL VAL B . n 
B 1 14  GLN 14  13  13  GLN GLN B . n 
B 1 15  PRO 15  14  14  PRO PRO B . n 
B 1 16  GLY 16  15  15  GLY GLY B . n 
B 1 17  ARG 17  16  16  ARG ARG B . n 
B 1 18  SER 18  17  17  SER SER B . n 
B 1 19  LEU 19  18  18  LEU LEU B . n 
B 1 20  ARG 20  19  19  ARG ARG B . n 
B 1 21  LEU 21  20  20  LEU LEU B . n 
B 1 22  SER 22  21  21  SER SER B . n 
B 1 23  CYS 23  22  22  CYS CYS B . n 
B 1 24  SER 24  23  23  SER SER B . n 
B 1 25  ALA 25  24  24  ALA ALA B . n 
B 1 26  SER 26  25  25  SER SER B . n 
B 1 27  GLY 27  26  26  GLY GLY B . n 
B 1 28  PHE 28  27  27  PHE PHE B . n 
B 1 29  THR 29  28  28  THR THR B . n 
B 1 30  PHE 30  29  29  PHE PHE B . n 
B 1 31  GLY 31  30  30  GLY GLY B . n 
B 1 32  ASP 32  31  31  ASP ASP B . n 
B 1 33  TYR 33  32  32  TYR TYR B . n 
B 1 34  ALA 34  33  33  ALA ALA B . n 
B 1 35  MET 35  34  34  MET MET B . n 
B 1 36  SER 36  35  35  SER SER B . n 
B 1 37  TRP 37  36  36  TRP TRP B . n 
B 1 38  PHE 38  37  37  PHE PHE B . n 
B 1 39  ARG 39  38  38  ARG ARG B . n 
B 1 40  LEU 40  39  39  LEU LEU B . n 
B 1 41  ALA 41  40  40  ALA ALA B . n 
B 1 42  PRO 42  41  41  PRO PRO B . n 
B 1 43  GLY 43  42  42  GLY GLY B . n 
B 1 44  LYS 44  43  43  LYS LYS B . n 
B 1 45  GLY 45  44  44  GLY GLY B . n 
B 1 46  LEU 46  45  45  LEU LEU B . n 
B 1 47  GLU 47  46  46  GLU GLU B . n 
B 1 48  TRP 48  47  47  TRP TRP B . n 
B 1 49  VAL 49  48  48  VAL VAL B . n 
B 1 50  GLY 50  49  49  GLY GLY B . n 
B 1 51  LEU 51  50  50  LEU LEU B . n 
B 1 52  ILE 52  51  51  ILE ILE B . n 
B 1 53  LYS 53  52  52  LYS LYS B . n 
B 1 54  SER 54  53  53  SER SER B . n 
B 1 55  ARG 55  54  54  ARG ARG B . n 
B 1 56  ALA 56  55  55  ALA ALA B . n 
B 1 57  ILE 57  56  56  ILE ILE B . n 
B 1 58  ASP 58  57  57  ASP ASP B . n 
B 1 59  GLY 59  58  58  GLY GLY B . n 
B 1 60  THR 60  59  59  THR THR B . n 
B 1 61  PRO 61  60  60  PRO PRO B . n 
B 1 62  GLN 62  61  61  GLN GLN B . n 
B 1 63  TYR 63  62  62  TYR TYR B . n 
B 1 64  ALA 64  63  63  ALA ALA B . n 
B 1 65  ALA 65  64  64  ALA ALA B . n 
B 1 66  SER 66  65  65  SER SER B . n 
B 1 67  VAL 67  66  66  VAL VAL B . n 
B 1 68  LYS 68  67  67  LYS LYS B . n 
B 1 69  GLY 69  68  68  GLY GLY B . n 
B 1 70  ARG 70  69  69  ARG ARG B . n 
B 1 71  PHE 71  70  70  PHE PHE B . n 
B 1 72  THR 72  71  71  THR THR B . n 
B 1 73  ILE 73  72  72  ILE ILE B . n 
B 1 74  SER 74  73  73  SER SER B . n 
B 1 75  ARG 75  74  74  ARG ARG B . n 
B 1 76  ASP 76  75  75  ASP ASP B . n 
B 1 77  ASP 77  76  76  ASP ASP B . n 
B 1 78  SER 78  77  77  SER SER B . n 
B 1 79  ASN 79  78  78  ASN ASN B . n 
B 1 80  SER 80  79  79  SER SER B . n 
B 1 81  ILE 81  80  80  ILE ILE B . n 
B 1 82  ALA 82  81  81  ALA ALA B . n 
B 1 83  TYR 83  82  82  TYR TYR B . n 
B 1 84  LEU 84  83  83  LEU LEU B . n 
B 1 85  GLN 85  84  84  GLN GLN B . n 
B 1 86  MET 86  85  85  MET MET B . n 
B 1 87  ASN 87  86  86  ASN ASN B . n 
B 1 88  SER 88  87  87  SER SER B . n 
B 1 89  LEU 89  88  88  LEU LEU B . n 
B 1 90  THR 90  89  89  THR THR B . n 
B 1 91  THR 91  90  90  THR THR B . n 
B 1 92  GLU 92  91  91  GLU GLU B . n 
B 1 93  ASP 93  92  92  ASP ASP B . n 
B 1 94  THR 94  93  93  THR THR B . n 
B 1 95  ALA 95  94  94  ALA ALA B . n 
B 1 96  ILE 96  95  95  ILE ILE B . n 
B 1 97  TYR 97  96  96  TYR TYR B . n 
B 1 98  TYR 98  97  97  TYR TYR B . n 
B 1 99  CYS 99  98  98  CYS CYS B . n 
B 1 100 ALA 100 99  99  ALA ALA B . n 
B 1 101 ARG 101 100 100 ARG ARG B . n 
B 1 102 ASP 102 101 101 ASP ASP B . n 
B 1 103 PHE 103 102 102 PHE PHE B . n 
B 1 104 TYR 104 103 103 TYR TYR B . n 
B 1 105 ASP 105 104 104 ASP ASP B . n 
B 1 106 PHE 106 105 105 PHE PHE B . n 
B 1 107 TRP 107 106 106 TRP TRP B . n 
B 1 108 ASN 108 107 107 ASN ASN B . n 
B 1 109 GLU 109 108 108 GLU GLU B . n 
B 1 110 PHE 110 109 109 PHE PHE B . n 
B 1 111 SER 111 110 110 SER SER B . n 
B 1 112 HIS 112 111 111 HIS HIS B . n 
B 1 113 ARG 113 112 112 ARG ARG B . n 
B 1 114 THR 114 113 113 THR THR B . n 
B 1 115 PHE 115 114 114 PHE PHE B . n 
B 1 116 ASP 116 115 115 ASP ASP B . n 
B 1 117 PHE 117 116 116 PHE PHE B . n 
B 1 118 TRP 118 117 117 TRP TRP B . n 
B 1 119 GLY 119 118 118 GLY GLY B . n 
B 1 120 GLN 120 119 119 GLN GLN B . n 
B 1 121 GLY 121 120 120 GLY GLY B . n 
B 1 122 THR 122 121 121 THR THR B . n 
B 1 123 LEU 123 122 122 LEU LEU B . n 
B 1 124 VAL 124 123 123 VAL VAL B . n 
B 1 125 THR 125 124 124 THR THR B . n 
B 1 126 VAL 126 125 125 VAL VAL B . n 
B 1 127 SER 127 126 126 SER SER B . n 
B 1 128 SER 128 127 127 SER SER B . n 
B 1 129 SER 129 128 ?   ?   ?   B . n 
B 1 130 GLY 130 129 ?   ?   ?   B . n 
B 1 131 GLY 131 130 ?   ?   ?   B . n 
B 1 132 GLY 132 131 ?   ?   ?   B . n 
B 1 133 GLY 133 132 ?   ?   ?   B . n 
B 1 134 SER 134 133 ?   ?   ?   B . n 
B 1 135 GLY 135 134 ?   ?   ?   B . n 
B 1 136 GLY 136 135 ?   ?   ?   B . n 
B 1 137 GLY 137 136 ?   ?   ?   B . n 
B 1 138 GLY 138 137 ?   ?   ?   B . n 
B 1 139 SER 139 138 ?   ?   ?   B . n 
B 1 140 GLY 140 139 ?   ?   ?   B . n 
B 1 141 GLY 141 140 ?   ?   ?   B . n 
B 1 142 GLY 142 141 ?   ?   ?   B . n 
B 1 143 GLY 143 142 ?   ?   ?   B . n 
B 1 144 SER 144 143 ?   ?   ?   B . n 
B 1 145 GLY 145 144 ?   ?   ?   B . n 
B 1 146 GLY 146 145 ?   ?   ?   B . n 
B 1 147 GLY 147 146 ?   ?   ?   B . n 
B 1 148 GLY 148 147 ?   ?   ?   B . n 
B 1 149 GLN 149 148 ?   ?   ?   B . n 
B 1 150 SER 150 149 ?   ?   ?   B . n 
B 1 151 ALA 151 150 150 ALA ALA B . n 
B 1 152 LEU 152 151 151 LEU LEU B . n 
B 1 153 THR 153 152 152 THR THR B . n 
B 1 154 GLN 154 153 153 GLN GLN B . n 
B 1 155 PRO 155 154 154 PRO PRO B . n 
B 1 156 ALA 156 155 155 ALA ALA B . n 
B 1 157 SER 157 156 156 SER SER B . n 
B 1 158 ALA 158 157 157 ALA ALA B . n 
B 1 159 SER 159 158 158 SER SER B . n 
B 1 160 GLY 160 159 159 GLY GLY B . n 
B 1 161 SER 161 160 160 SER SER B . n 
B 1 162 PRO 162 161 161 PRO PRO B . n 
B 1 163 GLY 163 162 162 GLY GLY B . n 
B 1 164 GLN 164 163 163 GLN GLN B . n 
B 1 165 SER 165 164 164 SER SER B . n 
B 1 166 VAL 166 165 165 VAL VAL B . n 
B 1 167 THR 167 166 166 THR THR B . n 
B 1 168 ILE 168 167 167 ILE ILE B . n 
B 1 169 THR 169 168 168 THR THR B . n 
B 1 170 CYS 170 169 169 CYS CYS B . n 
B 1 171 THR 171 170 170 THR THR B . n 
B 1 172 GLY 172 171 171 GLY GLY B . n 
B 1 173 SER 173 172 172 SER SER B . n 
B 1 174 SER 174 173 173 SER SER B . n 
B 1 175 SER 175 174 174 SER SER B . n 
B 1 176 ASP 176 175 175 ASP ASP B . n 
B 1 177 VAL 177 176 176 VAL VAL B . n 
B 1 178 GLY 178 177 177 GLY GLY B . n 
B 1 179 GLY 179 178 178 GLY GLY B . n 
B 1 180 TYR 180 179 179 TYR TYR B . n 
B 1 181 LYS 181 180 180 LYS LYS B . n 
B 1 182 TYR 182 181 181 TYR TYR B . n 
B 1 183 VAL 183 182 182 VAL VAL B . n 
B 1 184 SER 184 183 183 SER SER B . n 
B 1 185 TRP 185 184 184 TRP TRP B . n 
B 1 186 TYR 186 185 185 TYR TYR B . n 
B 1 187 GLN 187 186 186 GLN GLN B . n 
B 1 188 HIS 188 187 187 HIS HIS B . n 
B 1 189 HIS 189 188 188 HIS HIS B . n 
B 1 190 PRO 190 189 189 PRO PRO B . n 
B 1 191 GLY 191 190 190 GLY GLY B . n 
B 1 192 LYS 192 191 191 LYS LYS B . n 
B 1 193 ALA 193 192 192 ALA ALA B . n 
B 1 194 PRO 194 193 193 PRO PRO B . n 
B 1 195 LYS 195 194 194 LYS LYS B . n 
B 1 196 LEU 196 195 195 LEU LEU B . n 
B 1 197 MET 197 196 196 MET MET B . n 
B 1 198 ILE 198 197 197 ILE ILE B . n 
B 1 199 TYR 199 198 198 TYR TYR B . n 
B 1 200 GLU 200 199 199 GLU GLU B . n 
B 1 201 VAL 201 200 200 VAL VAL B . n 
B 1 202 SER 202 201 201 SER SER B . n 
B 1 203 LYS 203 202 202 LYS LYS B . n 
B 1 204 ARG 204 203 203 ARG ARG B . n 
B 1 205 PRO 205 204 204 PRO PRO B . n 
B 1 206 SER 206 205 205 SER SER B . n 
B 1 207 GLY 207 206 206 GLY GLY B . n 
B 1 208 VAL 208 207 207 VAL VAL B . n 
B 1 209 PRO 209 208 208 PRO PRO B . n 
B 1 210 ASP 210 209 209 ASP ASP B . n 
B 1 211 ARG 211 210 210 ARG ARG B . n 
B 1 212 PHE 212 211 211 PHE PHE B . n 
B 1 213 SER 213 212 212 SER SER B . n 
B 1 214 GLY 214 213 213 GLY GLY B . n 
B 1 215 SER 215 214 214 SER SER B . n 
B 1 216 LYS 216 215 215 LYS LYS B . n 
B 1 217 SER 217 216 216 SER SER B . n 
B 1 218 GLY 218 217 217 GLY GLY B . n 
B 1 219 ASN 219 218 218 ASN ASN B . n 
B 1 220 MET 220 219 219 MET MET B . n 
B 1 221 ALA 221 220 220 ALA ALA B . n 
B 1 222 SER 222 221 221 SER SER B . n 
B 1 223 LEU 223 222 222 LEU LEU B . n 
B 1 224 THR 224 223 223 THR THR B . n 
B 1 225 VAL 225 224 224 VAL VAL B . n 
B 1 226 SER 226 225 225 SER SER B . n 
B 1 227 GLY 227 226 226 GLY GLY B . n 
B 1 228 LEU 228 227 227 LEU LEU B . n 
B 1 229 GLN 229 228 228 GLN GLN B . n 
B 1 230 ALA 230 229 229 ALA ALA B . n 
B 1 231 GLU 231 230 230 GLU GLU B . n 
B 1 232 ASP 232 231 231 ASP ASP B . n 
B 1 233 GLU 233 232 232 GLU GLU B . n 
B 1 234 ALA 234 233 233 ALA ALA B . n 
B 1 235 ASP 235 234 234 ASP ASP B . n 
B 1 236 TYR 236 235 235 TYR TYR B . n 
B 1 237 TYR 237 236 236 TYR TYR B . n 
B 1 238 CYS 238 237 237 CYS CYS B . n 
B 1 239 SER 239 238 238 SER SER B . n 
B 1 240 SER 240 239 239 SER SER B . n 
B 1 241 TYR 241 240 240 TYR TYR B . n 
B 1 242 ALA 242 241 241 ALA ALA B . n 
B 1 243 GLY 243 242 242 GLY GLY B . n 
B 1 244 SER 244 243 243 SER SER B . n 
B 1 245 TYR 245 244 244 TYR TYR B . n 
B 1 246 ASN 246 245 245 ASN ASN B . n 
B 1 247 PHE 247 246 246 PHE PHE B . n 
B 1 248 TYR 248 247 247 TYR TYR B . n 
B 1 249 VAL 249 248 248 VAL VAL B . n 
B 1 250 PHE 250 249 249 PHE PHE B . n 
B 1 251 GLY 251 250 250 GLY GLY B . n 
B 1 252 ASN 252 251 251 ASN ASN B . n 
B 1 253 GLY 253 252 252 GLY GLY B . n 
B 1 254 THR 254 253 253 THR THR B . n 
B 1 255 LYS 255 254 254 LYS LYS B . n 
B 1 256 VAL 256 255 255 VAL VAL B . n 
B 1 257 THR 257 256 256 THR THR B . n 
B 1 258 VAL 258 257 257 VAL VAL B . n 
B 1 259 LEU 259 258 258 LEU LEU B . n 
B 1 260 GLY 260 259 259 GLY GLY B . n 
B 1 261 HIS 261 260 ?   ?   ?   B . n 
B 1 262 HIS 262 261 ?   ?   ?   B . n 
B 1 263 HIS 263 262 ?   ?   ?   B . n 
B 1 264 HIS 264 263 ?   ?   ?   B . n 
B 1 265 HIS 265 264 ?   ?   ?   B . n 
C 1 1   ASP 1   0   ?   ?   ?   C . n 
C 1 2   GLU 2   1   1   GLU GLU C . n 
C 1 3   VAL 3   2   2   VAL VAL C . n 
C 1 4   GLN 4   3   3   GLN GLN C . n 
C 1 5   LEU 5   4   4   LEU LEU C . n 
C 1 6   VAL 6   5   5   VAL VAL C . n 
C 1 7   GLU 7   6   6   GLU GLU C . n 
C 1 8   SER 8   7   7   SER SER C . n 
C 1 9   GLY 9   8   8   GLY GLY C . n 
C 1 10  GLY 10  9   9   GLY GLY C . n 
C 1 11  GLY 11  10  10  GLY GLY C . n 
C 1 12  LEU 12  11  11  LEU LEU C . n 
C 1 13  VAL 13  12  12  VAL VAL C . n 
C 1 14  GLN 14  13  13  GLN GLN C . n 
C 1 15  PRO 15  14  14  PRO PRO C . n 
C 1 16  GLY 16  15  15  GLY GLY C . n 
C 1 17  ARG 17  16  16  ARG ARG C . n 
C 1 18  SER 18  17  17  SER SER C . n 
C 1 19  LEU 19  18  18  LEU LEU C . n 
C 1 20  ARG 20  19  19  ARG ARG C . n 
C 1 21  LEU 21  20  20  LEU LEU C . n 
C 1 22  SER 22  21  21  SER SER C . n 
C 1 23  CYS 23  22  22  CYS CYS C . n 
C 1 24  SER 24  23  23  SER SER C . n 
C 1 25  ALA 25  24  24  ALA ALA C . n 
C 1 26  SER 26  25  25  SER SER C . n 
C 1 27  GLY 27  26  26  GLY GLY C . n 
C 1 28  PHE 28  27  27  PHE PHE C . n 
C 1 29  THR 29  28  28  THR THR C . n 
C 1 30  PHE 30  29  29  PHE PHE C . n 
C 1 31  GLY 31  30  30  GLY GLY C . n 
C 1 32  ASP 32  31  31  ASP ASP C . n 
C 1 33  TYR 33  32  32  TYR TYR C . n 
C 1 34  ALA 34  33  33  ALA ALA C . n 
C 1 35  MET 35  34  34  MET MET C . n 
C 1 36  SER 36  35  35  SER SER C . n 
C 1 37  TRP 37  36  36  TRP TRP C . n 
C 1 38  PHE 38  37  37  PHE PHE C . n 
C 1 39  ARG 39  38  38  ARG ARG C . n 
C 1 40  LEU 40  39  39  LEU LEU C . n 
C 1 41  ALA 41  40  40  ALA ALA C . n 
C 1 42  PRO 42  41  41  PRO PRO C . n 
C 1 43  GLY 43  42  42  GLY GLY C . n 
C 1 44  LYS 44  43  43  LYS LYS C . n 
C 1 45  GLY 45  44  44  GLY GLY C . n 
C 1 46  LEU 46  45  45  LEU LEU C . n 
C 1 47  GLU 47  46  46  GLU GLU C . n 
C 1 48  TRP 48  47  47  TRP TRP C . n 
C 1 49  VAL 49  48  48  VAL VAL C . n 
C 1 50  GLY 50  49  49  GLY GLY C . n 
C 1 51  LEU 51  50  50  LEU LEU C . n 
C 1 52  ILE 52  51  51  ILE ILE C . n 
C 1 53  LYS 53  52  52  LYS LYS C . n 
C 1 54  SER 54  53  53  SER SER C . n 
C 1 55  ARG 55  54  54  ARG ARG C . n 
C 1 56  ALA 56  55  55  ALA ALA C . n 
C 1 57  ILE 57  56  56  ILE ILE C . n 
C 1 58  ASP 58  57  57  ASP ASP C . n 
C 1 59  GLY 59  58  58  GLY GLY C . n 
C 1 60  THR 60  59  59  THR THR C . n 
C 1 61  PRO 61  60  60  PRO PRO C . n 
C 1 62  GLN 62  61  61  GLN GLN C . n 
C 1 63  TYR 63  62  62  TYR TYR C . n 
C 1 64  ALA 64  63  63  ALA ALA C . n 
C 1 65  ALA 65  64  64  ALA ALA C . n 
C 1 66  SER 66  65  65  SER SER C . n 
C 1 67  VAL 67  66  66  VAL VAL C . n 
C 1 68  LYS 68  67  67  LYS LYS C . n 
C 1 69  GLY 69  68  68  GLY GLY C . n 
C 1 70  ARG 70  69  69  ARG ARG C . n 
C 1 71  PHE 71  70  70  PHE PHE C . n 
C 1 72  THR 72  71  71  THR THR C . n 
C 1 73  ILE 73  72  72  ILE ILE C . n 
C 1 74  SER 74  73  73  SER SER C . n 
C 1 75  ARG 75  74  74  ARG ARG C . n 
C 1 76  ASP 76  75  75  ASP ASP C . n 
C 1 77  ASP 77  76  76  ASP ASP C . n 
C 1 78  SER 78  77  77  SER SER C . n 
C 1 79  ASN 79  78  78  ASN ASN C . n 
C 1 80  SER 80  79  79  SER SER C . n 
C 1 81  ILE 81  80  80  ILE ILE C . n 
C 1 82  ALA 82  81  81  ALA ALA C . n 
C 1 83  TYR 83  82  82  TYR TYR C . n 
C 1 84  LEU 84  83  83  LEU LEU C . n 
C 1 85  GLN 85  84  84  GLN GLN C . n 
C 1 86  MET 86  85  85  MET MET C . n 
C 1 87  ASN 87  86  86  ASN ASN C . n 
C 1 88  SER 88  87  87  SER SER C . n 
C 1 89  LEU 89  88  88  LEU LEU C . n 
C 1 90  THR 90  89  89  THR THR C . n 
C 1 91  THR 91  90  90  THR THR C . n 
C 1 92  GLU 92  91  91  GLU GLU C . n 
C 1 93  ASP 93  92  92  ASP ASP C . n 
C 1 94  THR 94  93  93  THR THR C . n 
C 1 95  ALA 95  94  94  ALA ALA C . n 
C 1 96  ILE 96  95  95  ILE ILE C . n 
C 1 97  TYR 97  96  96  TYR TYR C . n 
C 1 98  TYR 98  97  97  TYR TYR C . n 
C 1 99  CYS 99  98  98  CYS CYS C . n 
C 1 100 ALA 100 99  99  ALA ALA C . n 
C 1 101 ARG 101 100 100 ARG ARG C . n 
C 1 102 ASP 102 101 101 ASP ASP C . n 
C 1 103 PHE 103 102 102 PHE PHE C . n 
C 1 104 TYR 104 103 103 TYR TYR C . n 
C 1 105 ASP 105 104 104 ASP ASP C . n 
C 1 106 PHE 106 105 105 PHE PHE C . n 
C 1 107 TRP 107 106 106 TRP TRP C . n 
C 1 108 ASN 108 107 107 ASN ASN C . n 
C 1 109 GLU 109 108 108 GLU GLU C . n 
C 1 110 PHE 110 109 109 PHE PHE C . n 
C 1 111 SER 111 110 110 SER SER C . n 
C 1 112 HIS 112 111 111 HIS HIS C . n 
C 1 113 ARG 113 112 112 ARG ARG C . n 
C 1 114 THR 114 113 113 THR THR C . n 
C 1 115 PHE 115 114 114 PHE PHE C . n 
C 1 116 ASP 116 115 115 ASP ASP C . n 
C 1 117 PHE 117 116 116 PHE PHE C . n 
C 1 118 TRP 118 117 117 TRP TRP C . n 
C 1 119 GLY 119 118 118 GLY GLY C . n 
C 1 120 GLN 120 119 119 GLN GLN C . n 
C 1 121 GLY 121 120 120 GLY GLY C . n 
C 1 122 THR 122 121 121 THR THR C . n 
C 1 123 LEU 123 122 122 LEU LEU C . n 
C 1 124 VAL 124 123 123 VAL VAL C . n 
C 1 125 THR 125 124 124 THR THR C . n 
C 1 126 VAL 126 125 125 VAL VAL C . n 
C 1 127 SER 127 126 126 SER SER C . n 
C 1 128 SER 128 127 127 SER SER C . n 
C 1 129 SER 129 128 ?   ?   ?   C . n 
C 1 130 GLY 130 129 ?   ?   ?   C . n 
C 1 131 GLY 131 130 ?   ?   ?   C . n 
C 1 132 GLY 132 131 ?   ?   ?   C . n 
C 1 133 GLY 133 132 ?   ?   ?   C . n 
C 1 134 SER 134 133 ?   ?   ?   C . n 
C 1 135 GLY 135 134 ?   ?   ?   C . n 
C 1 136 GLY 136 135 ?   ?   ?   C . n 
C 1 137 GLY 137 136 ?   ?   ?   C . n 
C 1 138 GLY 138 137 ?   ?   ?   C . n 
C 1 139 SER 139 138 ?   ?   ?   C . n 
C 1 140 GLY 140 139 ?   ?   ?   C . n 
C 1 141 GLY 141 140 ?   ?   ?   C . n 
C 1 142 GLY 142 141 ?   ?   ?   C . n 
C 1 143 GLY 143 142 ?   ?   ?   C . n 
C 1 144 SER 144 143 ?   ?   ?   C . n 
C 1 145 GLY 145 144 ?   ?   ?   C . n 
C 1 146 GLY 146 145 ?   ?   ?   C . n 
C 1 147 GLY 147 146 ?   ?   ?   C . n 
C 1 148 GLY 148 147 ?   ?   ?   C . n 
C 1 149 GLN 149 148 148 GLN GLN C . n 
C 1 150 SER 150 149 149 SER SER C . n 
C 1 151 ALA 151 150 150 ALA ALA C . n 
C 1 152 LEU 152 151 151 LEU LEU C . n 
C 1 153 THR 153 152 152 THR THR C . n 
C 1 154 GLN 154 153 153 GLN GLN C . n 
C 1 155 PRO 155 154 154 PRO PRO C . n 
C 1 156 ALA 156 155 155 ALA ALA C . n 
C 1 157 SER 157 156 156 SER SER C . n 
C 1 158 ALA 158 157 157 ALA ALA C . n 
C 1 159 SER 159 158 158 SER SER C . n 
C 1 160 GLY 160 159 159 GLY GLY C . n 
C 1 161 SER 161 160 160 SER SER C . n 
C 1 162 PRO 162 161 161 PRO PRO C . n 
C 1 163 GLY 163 162 162 GLY GLY C . n 
C 1 164 GLN 164 163 163 GLN GLN C . n 
C 1 165 SER 165 164 164 SER SER C . n 
C 1 166 VAL 166 165 165 VAL VAL C . n 
C 1 167 THR 167 166 166 THR THR C . n 
C 1 168 ILE 168 167 167 ILE ILE C . n 
C 1 169 THR 169 168 168 THR THR C . n 
C 1 170 CYS 170 169 169 CYS CYS C . n 
C 1 171 THR 171 170 170 THR THR C . n 
C 1 172 GLY 172 171 171 GLY GLY C . n 
C 1 173 SER 173 172 172 SER SER C . n 
C 1 174 SER 174 173 173 SER SER C . n 
C 1 175 SER 175 174 174 SER SER C . n 
C 1 176 ASP 176 175 175 ASP ASP C . n 
C 1 177 VAL 177 176 176 VAL VAL C . n 
C 1 178 GLY 178 177 177 GLY GLY C . n 
C 1 179 GLY 179 178 178 GLY GLY C . n 
C 1 180 TYR 180 179 179 TYR TYR C . n 
C 1 181 LYS 181 180 180 LYS LYS C . n 
C 1 182 TYR 182 181 181 TYR TYR C . n 
C 1 183 VAL 183 182 182 VAL VAL C . n 
C 1 184 SER 184 183 183 SER SER C . n 
C 1 185 TRP 185 184 184 TRP TRP C . n 
C 1 186 TYR 186 185 185 TYR TYR C . n 
C 1 187 GLN 187 186 186 GLN GLN C . n 
C 1 188 HIS 188 187 187 HIS HIS C . n 
C 1 189 HIS 189 188 188 HIS HIS C . n 
C 1 190 PRO 190 189 189 PRO PRO C . n 
C 1 191 GLY 191 190 190 GLY GLY C . n 
C 1 192 LYS 192 191 191 LYS LYS C . n 
C 1 193 ALA 193 192 192 ALA ALA C . n 
C 1 194 PRO 194 193 193 PRO PRO C . n 
C 1 195 LYS 195 194 194 LYS LYS C . n 
C 1 196 LEU 196 195 195 LEU LEU C . n 
C 1 197 MET 197 196 196 MET MET C . n 
C 1 198 ILE 198 197 197 ILE ILE C . n 
C 1 199 TYR 199 198 198 TYR TYR C . n 
C 1 200 GLU 200 199 199 GLU GLU C . n 
C 1 201 VAL 201 200 200 VAL VAL C . n 
C 1 202 SER 202 201 201 SER SER C . n 
C 1 203 LYS 203 202 202 LYS LYS C . n 
C 1 204 ARG 204 203 203 ARG ARG C . n 
C 1 205 PRO 205 204 204 PRO PRO C . n 
C 1 206 SER 206 205 205 SER SER C . n 
C 1 207 GLY 207 206 206 GLY GLY C . n 
C 1 208 VAL 208 207 207 VAL VAL C . n 
C 1 209 PRO 209 208 208 PRO PRO C . n 
C 1 210 ASP 210 209 209 ASP ASP C . n 
C 1 211 ARG 211 210 210 ARG ARG C . n 
C 1 212 PHE 212 211 211 PHE PHE C . n 
C 1 213 SER 213 212 212 SER SER C . n 
C 1 214 GLY 214 213 213 GLY GLY C . n 
C 1 215 SER 215 214 214 SER SER C . n 
C 1 216 LYS 216 215 215 LYS LYS C . n 
C 1 217 SER 217 216 216 SER SER C . n 
C 1 218 GLY 218 217 217 GLY GLY C . n 
C 1 219 ASN 219 218 218 ASN ASN C . n 
C 1 220 MET 220 219 219 MET MET C . n 
C 1 221 ALA 221 220 220 ALA ALA C . n 
C 1 222 SER 222 221 221 SER SER C . n 
C 1 223 LEU 223 222 222 LEU LEU C . n 
C 1 224 THR 224 223 223 THR THR C . n 
C 1 225 VAL 225 224 224 VAL VAL C . n 
C 1 226 SER 226 225 225 SER SER C . n 
C 1 227 GLY 227 226 226 GLY GLY C . n 
C 1 228 LEU 228 227 227 LEU LEU C . n 
C 1 229 GLN 229 228 228 GLN GLN C . n 
C 1 230 ALA 230 229 229 ALA ALA C . n 
C 1 231 GLU 231 230 230 GLU GLU C . n 
C 1 232 ASP 232 231 231 ASP ASP C . n 
C 1 233 GLU 233 232 232 GLU GLU C . n 
C 1 234 ALA 234 233 233 ALA ALA C . n 
C 1 235 ASP 235 234 234 ASP ASP C . n 
C 1 236 TYR 236 235 235 TYR TYR C . n 
C 1 237 TYR 237 236 236 TYR TYR C . n 
C 1 238 CYS 238 237 237 CYS CYS C . n 
C 1 239 SER 239 238 238 SER SER C . n 
C 1 240 SER 240 239 239 SER SER C . n 
C 1 241 TYR 241 240 240 TYR TYR C . n 
C 1 242 ALA 242 241 241 ALA ALA C . n 
C 1 243 GLY 243 242 242 GLY GLY C . n 
C 1 244 SER 244 243 243 SER SER C . n 
C 1 245 TYR 245 244 244 TYR TYR C . n 
C 1 246 ASN 246 245 245 ASN ASN C . n 
C 1 247 PHE 247 246 246 PHE PHE C . n 
C 1 248 TYR 248 247 247 TYR TYR C . n 
C 1 249 VAL 249 248 248 VAL VAL C . n 
C 1 250 PHE 250 249 249 PHE PHE C . n 
C 1 251 GLY 251 250 250 GLY GLY C . n 
C 1 252 ASN 252 251 251 ASN ASN C . n 
C 1 253 GLY 253 252 252 GLY GLY C . n 
C 1 254 THR 254 253 253 THR THR C . n 
C 1 255 LYS 255 254 254 LYS LYS C . n 
C 1 256 VAL 256 255 255 VAL VAL C . n 
C 1 257 THR 257 256 256 THR THR C . n 
C 1 258 VAL 258 257 257 VAL VAL C . n 
C 1 259 LEU 259 258 258 LEU LEU C . n 
C 1 260 GLY 260 259 ?   ?   ?   C . n 
C 1 261 HIS 261 260 ?   ?   ?   C . n 
C 1 262 HIS 262 261 ?   ?   ?   C . n 
C 1 263 HIS 263 262 ?   ?   ?   C . n 
C 1 264 HIS 264 263 ?   ?   ?   C . n 
C 1 265 HIS 265 264 ?   ?   ?   C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 SO4 1  301 1   SO4 SO4 A . 
E 2 SO4 1  302 4   SO4 SO4 A . 
F 2 SO4 1  301 2   SO4 SO4 B . 
G 2 SO4 1  301 3   SO4 SO4 C . 
H 3 HOH 1  401 65  HOH HOH A . 
H 3 HOH 2  402 151 HOH HOH A . 
H 3 HOH 3  403 57  HOH HOH A . 
H 3 HOH 4  404 77  HOH HOH A . 
H 3 HOH 5  405 110 HOH HOH A . 
H 3 HOH 6  406 150 HOH HOH A . 
H 3 HOH 7  407 52  HOH HOH A . 
H 3 HOH 8  408 84  HOH HOH A . 
H 3 HOH 9  409 120 HOH HOH A . 
H 3 HOH 10 410 40  HOH HOH A . 
H 3 HOH 11 411 128 HOH HOH A . 
H 3 HOH 12 412 19  HOH HOH A . 
H 3 HOH 13 413 26  HOH HOH A . 
H 3 HOH 14 414 126 HOH HOH A . 
H 3 HOH 15 415 64  HOH HOH A . 
H 3 HOH 16 416 108 HOH HOH A . 
H 3 HOH 17 417 133 HOH HOH A . 
H 3 HOH 18 418 113 HOH HOH A . 
H 3 HOH 19 419 48  HOH HOH A . 
H 3 HOH 20 420 20  HOH HOH A . 
H 3 HOH 21 421 6   HOH HOH A . 
H 3 HOH 22 422 43  HOH HOH A . 
H 3 HOH 23 423 95  HOH HOH A . 
H 3 HOH 24 424 68  HOH HOH A . 
H 3 HOH 25 425 124 HOH HOH A . 
H 3 HOH 26 426 4   HOH HOH A . 
H 3 HOH 27 427 89  HOH HOH A . 
H 3 HOH 28 428 127 HOH HOH A . 
H 3 HOH 29 429 139 HOH HOH A . 
H 3 HOH 30 430 10  HOH HOH A . 
H 3 HOH 31 431 50  HOH HOH A . 
H 3 HOH 32 432 121 HOH HOH A . 
H 3 HOH 33 433 157 HOH HOH A . 
H 3 HOH 34 434 42  HOH HOH A . 
H 3 HOH 35 435 61  HOH HOH A . 
H 3 HOH 36 436 134 HOH HOH A . 
H 3 HOH 37 437 130 HOH HOH A . 
H 3 HOH 38 438 116 HOH HOH A . 
H 3 HOH 39 439 72  HOH HOH A . 
H 3 HOH 40 440 17  HOH HOH A . 
H 3 HOH 41 441 22  HOH HOH A . 
H 3 HOH 42 442 53  HOH HOH A . 
H 3 HOH 43 443 81  HOH HOH A . 
H 3 HOH 44 444 125 HOH HOH A . 
H 3 HOH 45 445 135 HOH HOH A . 
H 3 HOH 46 446 129 HOH HOH A . 
H 3 HOH 47 447 118 HOH HOH A . 
H 3 HOH 48 448 119 HOH HOH A . 
H 3 HOH 49 449 115 HOH HOH A . 
H 3 HOH 50 450 102 HOH HOH A . 
H 3 HOH 51 451 73  HOH HOH A . 
H 3 HOH 52 452 149 HOH HOH A . 
H 3 HOH 53 453 117 HOH HOH A . 
H 3 HOH 54 454 60  HOH HOH A . 
H 3 HOH 55 455 92  HOH HOH A . 
H 3 HOH 56 456 148 HOH HOH A . 
H 3 HOH 57 457 96  HOH HOH A . 
I 3 HOH 1  401 30  HOH HOH B . 
I 3 HOH 2  402 56  HOH HOH B . 
I 3 HOH 3  403 16  HOH HOH B . 
I 3 HOH 4  404 79  HOH HOH B . 
I 3 HOH 5  405 66  HOH HOH B . 
I 3 HOH 6  406 14  HOH HOH B . 
I 3 HOH 7  407 145 HOH HOH B . 
I 3 HOH 8  408 5   HOH HOH B . 
I 3 HOH 9  409 21  HOH HOH B . 
I 3 HOH 10 410 70  HOH HOH B . 
I 3 HOH 11 411 138 HOH HOH B . 
I 3 HOH 12 412 80  HOH HOH B . 
I 3 HOH 13 413 3   HOH HOH B . 
I 3 HOH 14 414 137 HOH HOH B . 
I 3 HOH 15 415 44  HOH HOH B . 
I 3 HOH 16 416 75  HOH HOH B . 
I 3 HOH 17 417 12  HOH HOH B . 
I 3 HOH 18 418 82  HOH HOH B . 
I 3 HOH 19 419 15  HOH HOH B . 
I 3 HOH 20 420 156 HOH HOH B . 
I 3 HOH 21 421 45  HOH HOH B . 
I 3 HOH 22 422 131 HOH HOH B . 
I 3 HOH 23 423 146 HOH HOH B . 
I 3 HOH 24 424 78  HOH HOH B . 
I 3 HOH 25 425 112 HOH HOH B . 
I 3 HOH 26 426 104 HOH HOH B . 
I 3 HOH 27 427 18  HOH HOH B . 
I 3 HOH 28 428 106 HOH HOH B . 
I 3 HOH 29 429 47  HOH HOH B . 
I 3 HOH 30 430 86  HOH HOH B . 
I 3 HOH 31 431 37  HOH HOH B . 
I 3 HOH 32 432 87  HOH HOH B . 
I 3 HOH 33 433 29  HOH HOH B . 
I 3 HOH 34 434 33  HOH HOH B . 
I 3 HOH 35 435 31  HOH HOH B . 
I 3 HOH 36 436 49  HOH HOH B . 
I 3 HOH 37 437 91  HOH HOH B . 
I 3 HOH 38 438 51  HOH HOH B . 
I 3 HOH 39 439 111 HOH HOH B . 
I 3 HOH 40 440 101 HOH HOH B . 
I 3 HOH 41 441 147 HOH HOH B . 
I 3 HOH 42 442 36  HOH HOH B . 
I 3 HOH 43 443 152 HOH HOH B . 
I 3 HOH 44 444 105 HOH HOH B . 
I 3 HOH 45 445 107 HOH HOH B . 
I 3 HOH 46 446 94  HOH HOH B . 
I 3 HOH 47 447 136 HOH HOH B . 
I 3 HOH 48 448 100 HOH HOH B . 
I 3 HOH 49 449 153 HOH HOH B . 
I 3 HOH 50 450 93  HOH HOH B . 
J 3 HOH 1  401 46  HOH HOH C . 
J 3 HOH 2  402 109 HOH HOH C . 
J 3 HOH 3  403 23  HOH HOH C . 
J 3 HOH 4  404 103 HOH HOH C . 
J 3 HOH 5  405 144 HOH HOH C . 
J 3 HOH 6  406 83  HOH HOH C . 
J 3 HOH 7  407 38  HOH HOH C . 
J 3 HOH 8  408 155 HOH HOH C . 
J 3 HOH 9  409 142 HOH HOH C . 
J 3 HOH 10 410 132 HOH HOH C . 
J 3 HOH 11 411 41  HOH HOH C . 
J 3 HOH 12 412 143 HOH HOH C . 
J 3 HOH 13 413 58  HOH HOH C . 
J 3 HOH 14 414 63  HOH HOH C . 
J 3 HOH 15 415 71  HOH HOH C . 
J 3 HOH 16 416 2   HOH HOH C . 
J 3 HOH 17 417 8   HOH HOH C . 
J 3 HOH 18 418 24  HOH HOH C . 
J 3 HOH 19 419 39  HOH HOH C . 
J 3 HOH 20 420 98  HOH HOH C . 
J 3 HOH 21 421 13  HOH HOH C . 
J 3 HOH 22 422 62  HOH HOH C . 
J 3 HOH 23 423 7   HOH HOH C . 
J 3 HOH 24 424 35  HOH HOH C . 
J 3 HOH 25 425 76  HOH HOH C . 
J 3 HOH 26 426 69  HOH HOH C . 
J 3 HOH 27 427 34  HOH HOH C . 
J 3 HOH 28 428 67  HOH HOH C . 
J 3 HOH 29 429 88  HOH HOH C . 
J 3 HOH 30 430 9   HOH HOH C . 
J 3 HOH 31 431 54  HOH HOH C . 
J 3 HOH 32 432 25  HOH HOH C . 
J 3 HOH 33 433 85  HOH HOH C . 
J 3 HOH 34 434 32  HOH HOH C . 
J 3 HOH 35 435 1   HOH HOH C . 
J 3 HOH 36 436 55  HOH HOH C . 
J 3 HOH 37 437 99  HOH HOH C . 
J 3 HOH 38 438 11  HOH HOH C . 
J 3 HOH 39 439 154 HOH HOH C . 
J 3 HOH 40 440 114 HOH HOH C . 
J 3 HOH 41 441 90  HOH HOH C . 
J 3 HOH 42 442 97  HOH HOH C . 
J 3 HOH 43 443 28  HOH HOH C . 
J 3 HOH 44 444 123 HOH HOH C . 
J 3 HOH 45 445 74  HOH HOH C . 
J 3 HOH 46 446 122 HOH HOH C . 
J 3 HOH 47 447 140 HOH HOH C . 
J 3 HOH 48 448 59  HOH HOH C . 
J 3 HOH 49 449 27  HOH HOH C . 
J 3 HOH 50 450 141 HOH HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ASP 0   ? OD1 ? A ASP 1   OD1 
2  1 Y 1 A ASP 0   ? OD2 ? A ASP 1   OD2 
3  1 Y 1 A GLU 1   ? CG  ? A GLU 2   CG  
4  1 Y 1 A GLU 1   ? CD  ? A GLU 2   CD  
5  1 Y 1 A GLU 1   ? OE1 ? A GLU 2   OE1 
6  1 Y 1 A GLU 1   ? OE2 ? A GLU 2   OE2 
7  1 Y 1 A ASP 57  ? CG  ? A ASP 58  CG  
8  1 Y 1 A ASP 57  ? OD1 ? A ASP 58  OD1 
9  1 Y 1 A ASP 57  ? OD2 ? A ASP 58  OD2 
10 1 Y 1 A LYS 67  ? CG  ? A LYS 68  CG  
11 1 Y 1 A LYS 67  ? CD  ? A LYS 68  CD  
12 1 Y 1 A LYS 67  ? CE  ? A LYS 68  CE  
13 1 Y 1 A LYS 67  ? NZ  ? A LYS 68  NZ  
14 1 Y 1 A SER 160 ? OG  ? A SER 161 OG  
15 1 Y 1 A GLN 163 ? CG  ? A GLN 164 CG  
16 1 Y 1 A GLN 163 ? CD  ? A GLN 164 CD  
17 1 Y 1 A GLN 163 ? OE1 ? A GLN 164 OE1 
18 1 Y 1 A GLN 163 ? NE2 ? A GLN 164 NE2 
19 1 Y 1 A LYS 191 ? CG  ? A LYS 192 CG  
20 1 Y 1 A LYS 191 ? CD  ? A LYS 192 CD  
21 1 Y 1 A LYS 191 ? CE  ? A LYS 192 CE  
22 1 Y 1 A LYS 191 ? NZ  ? A LYS 192 NZ  
23 1 Y 1 A GLU 230 ? CG  ? A GLU 231 CG  
24 1 Y 1 A GLU 230 ? CD  ? A GLU 231 CD  
25 1 Y 1 A GLU 230 ? OE1 ? A GLU 231 OE1 
26 1 Y 1 A GLU 230 ? OE2 ? A GLU 231 OE2 
27 1 Y 1 B GLN 3   ? CG  ? B GLN 4   CG  
28 1 Y 1 B GLN 3   ? CD  ? B GLN 4   CD  
29 1 Y 1 B GLN 3   ? OE1 ? B GLN 4   OE1 
30 1 Y 1 B GLN 3   ? NE2 ? B GLN 4   NE2 
31 1 Y 1 B GLN 13  ? CG  ? B GLN 14  CG  
32 1 Y 1 B GLN 13  ? CD  ? B GLN 14  CD  
33 1 Y 1 B GLN 13  ? OE1 ? B GLN 14  OE1 
34 1 Y 1 B GLN 13  ? NE2 ? B GLN 14  NE2 
35 1 Y 1 B ARG 16  ? CG  ? B ARG 17  CG  
36 1 Y 1 B ARG 16  ? CD  ? B ARG 17  CD  
37 1 Y 1 B ARG 16  ? NE  ? B ARG 17  NE  
38 1 Y 1 B ARG 16  ? CZ  ? B ARG 17  CZ  
39 1 Y 1 B ARG 16  ? NH1 ? B ARG 17  NH1 
40 1 Y 1 B ARG 16  ? NH2 ? B ARG 17  NH2 
41 1 Y 1 B ILE 56  ? CG1 ? B ILE 57  CG1 
42 1 Y 1 B ILE 56  ? CG2 ? B ILE 57  CG2 
43 1 Y 1 B ILE 56  ? CD1 ? B ILE 57  CD1 
44 1 Y 1 B THR 59  ? OG1 ? B THR 60  OG1 
45 1 Y 1 B THR 59  ? CG2 ? B THR 60  CG2 
46 1 Y 1 B SER 65  ? OG  ? B SER 66  OG  
47 1 Y 1 B LYS 67  ? CG  ? B LYS 68  CG  
48 1 Y 1 B LYS 67  ? CD  ? B LYS 68  CD  
49 1 Y 1 B LYS 67  ? CE  ? B LYS 68  CE  
50 1 Y 1 B LYS 67  ? NZ  ? B LYS 68  NZ  
51 1 Y 1 B GLU 91  ? CG  ? B GLU 92  CG  
52 1 Y 1 B GLU 91  ? CD  ? B GLU 92  CD  
53 1 Y 1 B GLU 91  ? OE1 ? B GLU 92  OE1 
54 1 Y 1 B GLU 91  ? OE2 ? B GLU 92  OE2 
55 1 Y 1 B LYS 191 ? CD  ? B LYS 192 CD  
56 1 Y 1 B LYS 191 ? CE  ? B LYS 192 CE  
57 1 Y 1 B LYS 191 ? NZ  ? B LYS 192 NZ  
58 1 Y 1 B LYS 194 ? CE  ? B LYS 195 CE  
59 1 Y 1 B LYS 194 ? NZ  ? B LYS 195 NZ  
60 1 Y 1 B LEU 258 ? CG  ? B LEU 259 CG  
61 1 Y 1 B LEU 258 ? CD1 ? B LEU 259 CD1 
62 1 Y 1 B LEU 258 ? CD2 ? B LEU 259 CD2 
63 1 Y 1 C GLN 3   ? CG  ? C GLN 4   CG  
64 1 Y 1 C GLN 3   ? CD  ? C GLN 4   CD  
65 1 Y 1 C GLN 3   ? OE1 ? C GLN 4   OE1 
66 1 Y 1 C GLN 3   ? NE2 ? C GLN 4   NE2 
67 1 Y 1 C LYS 43  ? CG  ? C LYS 44  CG  
68 1 Y 1 C LYS 43  ? CD  ? C LYS 44  CD  
69 1 Y 1 C LYS 43  ? CE  ? C LYS 44  CE  
70 1 Y 1 C LYS 43  ? NZ  ? C LYS 44  NZ  
71 1 Y 1 C ARG 54  ? CG  ? C ARG 55  CG  
72 1 Y 1 C ARG 54  ? CD  ? C ARG 55  CD  
73 1 Y 1 C ARG 54  ? NE  ? C ARG 55  NE  
74 1 Y 1 C ARG 54  ? CZ  ? C ARG 55  CZ  
75 1 Y 1 C ARG 54  ? NH1 ? C ARG 55  NH1 
76 1 Y 1 C ARG 54  ? NH2 ? C ARG 55  NH2 
77 1 Y 1 C ASP 57  ? CG  ? C ASP 58  CG  
78 1 Y 1 C ASP 57  ? OD1 ? C ASP 58  OD1 
79 1 Y 1 C ASP 57  ? OD2 ? C ASP 58  OD2 
80 1 Y 1 C GLN 61  ? CG  ? C GLN 62  CG  
81 1 Y 1 C GLN 61  ? CD  ? C GLN 62  CD  
82 1 Y 1 C GLN 61  ? OE1 ? C GLN 62  OE1 
83 1 Y 1 C GLN 61  ? NE2 ? C GLN 62  NE2 
84 1 Y 1 C SER 65  ? OG  ? C SER 66  OG  
85 1 Y 1 C GLU 108 ? CG  ? C GLU 109 CG  
86 1 Y 1 C GLU 108 ? CD  ? C GLU 109 CD  
87 1 Y 1 C GLU 108 ? OE1 ? C GLU 109 OE1 
88 1 Y 1 C GLU 108 ? OE2 ? C GLU 109 OE2 
89 1 Y 1 C GLN 148 ? CG  ? C GLN 149 CG  
90 1 Y 1 C GLN 148 ? CD  ? C GLN 149 CD  
91 1 Y 1 C GLN 148 ? OE1 ? C GLN 149 OE1 
92 1 Y 1 C GLN 148 ? NE2 ? C GLN 149 NE2 
93 1 Y 1 C SER 149 ? OG  ? C SER 150 OG  
94 1 Y 1 C SER 243 ? OG  ? C SER 244 OG  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? Blu-Ice ? ? ? .           1 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20.1-4487 2 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           3 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           4 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9D7Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     96.544 
_cell.length_a_esd                 ? 
_cell.length_b                     103.963 
_cell.length_b_esd                 ? 
_cell.length_c                     85.088 
_cell.length_c_esd                 ? 
_cell.volume                       854028.585 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9D7Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9D7Y 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.55 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          51.84 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;The hanging drop contained 1 microliter of mother liquor combined with 1 microliter of 20 mg/mL b96.11 scFv protein solution. Crystals formed as shards within 24 hours at 293 K, with final crystals being selected from well conditions containing 0.1M Bis-Tris pH 6.5, 2.5M (NH4)2SO4
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-08-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9537 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'AUSTRALIAN SYNCHROTRON BEAMLINE MX2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9537 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   MX2 
_diffrn_source.pdbx_synchrotron_site       'Australian Synchrotron' 
# 
_reflns.B_iso_Wilson_estimate                          32.73 
_reflns.entry_id                                       9D7Y 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.60 
_reflns.d_resolution_low                               45.77 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     26242 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           85.66 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                1.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          3.92 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.968 
_reflns.pdbx_CC_star                                   0.992 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.1372 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.6 
_reflns_shell.d_res_low                                     2.69 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.68 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2526 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               1.9 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.94 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.362 
_reflns_shell.pdbx_CC_star                                  0.729 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          70.06 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               34.10 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9D7Y 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.60 
_refine.ls_d_res_low                             45.77 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     23377 
_refine.ls_number_reflns_R_free                  1806 
_refine.ls_number_reflns_R_work                  21571 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    86.67 
_refine.ls_percent_reflns_R_free                 7.73 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2329 
_refine.ls_R_factor_R_free                       0.3008 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2271 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          0.00 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 32.2931 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.4245 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.60 
_refine_hist.d_res_low                        45.77 
_refine_hist.number_atoms_solvent             157 
_refine_hist.number_atoms_total               5520 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5343 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         20 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0095  ? 5500 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.3159  ? 7473 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0728  ? 790  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0092  ? 959  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 17.0090 ? 778  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.pdbx_ens_id 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.ncs_model_details 
1 'X-RAY DIFFRACTION' d_2 ens_1 0.88154554133  ? ? ? 'Torsion NCS' A A ? ? ? ? 
2 'X-RAY DIFFRACTION' d_3 ens_1 0.902326567525 ? ? ? 'Torsion NCS' A A ? ? ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.60 2.67  . . 110 1307 68.79 . . . . 0.3298 . . . . . . . . . . . 0.3878 
'X-RAY DIFFRACTION' 2.67 2.75  . . 121 1433 76.51 . . . . 0.3321 . . . . . . . . . . . 0.4231 
'X-RAY DIFFRACTION' 2.75 2.84  . . 124 1510 79.94 . . . . 0.3184 . . . . . . . . . . . 0.4257 
'X-RAY DIFFRACTION' 2.84 2.94  . . 123 1526 81.07 . . . . 0.3018 . . . . . . . . . . . 0.3919 
'X-RAY DIFFRACTION' 2.94 3.06  . . 133 1547 81.71 . . . . 0.2786 . . . . . . . . . . . 0.3590 
'X-RAY DIFFRACTION' 3.06 3.20  . . 130 1617 86.36 . . . . 0.2590 . . . . . . . . . . . 0.3673 
'X-RAY DIFFRACTION' 3.20 3.36  . . 149 1679 87.93 . . . . 0.2461 . . . . . . . . . . . 0.3168 
'X-RAY DIFFRACTION' 3.37 3.58  . . 135 1805 93.99 . . . . 0.2206 . . . . . . . . . . . 0.3078 
'X-RAY DIFFRACTION' 3.58 3.85  . . 155 1776 93.47 . . . . 0.2115 . . . . . . . . . . . 0.2600 
'X-RAY DIFFRACTION' 3.85 4.24  . . 158 1817 95.50 . . . . 0.1922 . . . . . . . . . . . 0.2772 
'X-RAY DIFFRACTION' 4.24 4.85  . . 148 1814 94.28 . . . . 0.1660 . . . . . . . . . . . 0.2238 
'X-RAY DIFFRACTION' 4.85 6.11  . . 155 1858 93.76 . . . . 0.1966 . . . . . . . . . . . 0.2524 
'X-RAY DIFFRACTION' 6.11 45.77 . . 165 1882 92.46 . . . . 0.2153 . . . . . . . . . . . 0.2851 
# 
loop_
_struct_ncs_oper.id 
_struct_ncs_oper.code 
_struct_ncs_oper.matrix[1][1] 
_struct_ncs_oper.matrix[1][2] 
_struct_ncs_oper.matrix[1][3] 
_struct_ncs_oper.matrix[2][1] 
_struct_ncs_oper.matrix[2][2] 
_struct_ncs_oper.matrix[2][3] 
_struct_ncs_oper.matrix[3][1] 
_struct_ncs_oper.matrix[3][2] 
_struct_ncs_oper.matrix[3][3] 
_struct_ncs_oper.vector[1] 
_struct_ncs_oper.vector[2] 
_struct_ncs_oper.vector[3] 
_struct_ncs_oper.details 
1 given 0.529310793158  0.0173995231744 -0.848249574618 0.0216716666279 0.999186199809 0.0340187739016 0.848151179397 
-0.0363894861945 0.528502963268  75.9491220777 13.2296283517 -52.4041533939 ? 
2 given -0.473016962854 0.0268311128504 -0.880644675357 0.0346147338096 0.999330418807 0.0118547142535 0.880373087421 
-0.0248758000867 -0.473628991421 163.77929511  31.5160042877 73.0556116284  ? 
# 
loop_
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.id 
_struct_ncs_dom.details 
ens_1 d_1 
;(chain "A" and (resid 1 through 2 or (resid 3 and (name N or name CA or name C or name O or name CB )) or resid 4 through 12 or (resid 13 and (name N or name CA or name C or name O or name CB )) or resid 14 through 15 or (resid 16 and (name N or name CA or name C or name O or name CB )) or resid 17 through 42 or (resid 43 and (name N or name CA or name C or name O or name CB )) or resid 44 through 53 or (resid 54 through 57 and (name N or name CA or name C or name O or name CB )) or resid 58 or (resid 59 and (name N or name CA or name C or name O or name CB )) or resid 60 or (resid 61 and (name N or name CA or name C or name O or name CB )) or resid 62 through 64 or (resid 65 and (name N or name CA or name C or name O or name CB )) or resid 66 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 107 or (resid 108 and (name N or name CA or name C or name O or name CB )) or resid 109 through 193 or (resid 194 and (name N or name CA or name C or name O or name CB or name CG or name CD )) or resid 195 through 242 or (resid 243 and (name N or name CA or name C or name O or name CB )) or resid 244 through 257))
;
ens_1 d_2 
;(chain "B" and ((resid 1 and (name N or name CA or name C or name O or name CB )) or resid 2 through 42 or (resid 43 and (name N or name CA or name C or name O or name CB )) or resid 44 through 53 or (resid 54 through 57 and (name N or name CA or name C or name O or name CB )) or resid 58 through 60 or (resid 61 and (name N or name CA or name C or name O or name CB )) or resid 62 through 107 or (resid 108 and (name N or name CA or name C or name O or name CB )) or resid 109 through 159 or (resid 160 and (name N or name CA or name C or name O or name CB )) or resid 161 through 162 or (resid 163 and (name N or name CA or name C or name O or name CB )) or resid 164 through 190 or (resid 191 through 192 and (name N or name CA or name C or name O or name CB )) or resid 193 through 229 or (resid 230 and (name N or name CA or name C or name O or name CB )) or resid 231 through 242 or (resid 243 and (name N or name CA or name C or name O or name CB )) or resid 244 through 257))
;
ens_1 d_3 
;(chain "C" and ((resid 1 and (name N or name CA or name C or name O or name CB )) or resid 2 through 12 or (resid 13 and (name N or name CA or name C or name O or name CB )) or resid 14 through 15 or (resid 16 and (name N or name CA or name C or name O or name CB )) or resid 17 through 55 or (resid 56 through 57 and (name N or name CA or name C or name O or name CB )) or resid 58 or (resid 59 and (name N or name CA or name C or name O or name CB )) or resid 60 through 66 or (resid 67 and (name N or name CA or name C or name O or name CB )) or resid 68 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 127 or resid 150 through 159 or (resid 160 and (name N or name CA or name C or name O or name CB )) or resid 161 through 162 or (resid 163 and (name N or name CA or name C or name O or name CB )) or resid 164 through 190 or (resid 191 through 192 and (name N or name CA or name C or name O or name CB )) or (resid 193 through 194 and (name N or name CA or name C or name O or name CB or name CG or name CD )) or resid 195 through 229 or (resid 230 and (name N or name CA or name C or name O or name CB )) or resid 231 through 257))
;
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
ens_1 d_1 1 A GLU 2   . A VAL 258 . A GLU 1   A VAL 257 ? ? 
ens_1 d_2 1 B GLU 2   . B VAL 258 . B GLU 1   B VAL 257 ? ? 
ens_1 d_3 1 C GLU 2   . C SER 128 . C GLU 1   C SER 127 ? ? 
ens_1 d_3 2 C ALA 151 . C VAL 258 . C ALA 150 C VAL 257 ? ? 
# 
_struct_ncs_ens.id        ens_1 
_struct_ncs_ens.details   ? 
# 
loop_
_struct_ncs_ens_gen.ens_id 
_struct_ncs_ens_gen.dom_id_1 
_struct_ncs_ens_gen.dom_id_2 
_struct_ncs_ens_gen.oper_id 
ens_1 d_2 d_1 1 
ens_1 d_3 d_1 2 
# 
_struct.entry_id                     9D7Y 
_struct.title                        'Crystal structure of scFv corresponding to human autoantibody b96.11' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9D7Y 
_struct_keywords.text            'Autoantibody, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9D7Y 
_struct_ref.pdbx_db_accession          9D7Y 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9D7Y A 1 ? 265 ? 9D7Y 0 ? 264 ? 0 264 
2 1 9D7Y B 1 ? 265 ? 9D7Y 0 ? 264 ? 0 264 
3 1 9D7Y C 1 ? 265 ? 9D7Y 0 ? 264 ? 0 264 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,E,H 
2 1 B,F,I   
3 1 C,G,J   
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 29  ? TYR A 33  ? THR A 28  TYR A 32  5 ? 5 
HELX_P HELX_P2  AA2 ALA A 65  ? LYS A 68  ? ALA A 64  LYS A 67  5 ? 4 
HELX_P HELX_P3  AA3 THR A 90  ? THR A 94  ? THR A 89  THR A 93  5 ? 5 
HELX_P HELX_P4  AA4 ASP A 176 ? TYR A 180 ? ASP A 175 TYR A 179 5 ? 5 
HELX_P HELX_P5  AA5 GLN A 229 ? GLU A 233 ? GLN A 228 GLU A 232 5 ? 5 
HELX_P HELX_P6  AA6 ALA A 242 ? PHE A 247 ? ALA A 241 PHE A 246 1 ? 6 
HELX_P HELX_P7  AA7 THR B 29  ? TYR B 33  ? THR B 28  TYR B 32  5 ? 5 
HELX_P HELX_P8  AA8 THR B 90  ? THR B 94  ? THR B 89  THR B 93  5 ? 5 
HELX_P HELX_P9  AA9 GLN B 229 ? GLU B 233 ? GLN B 228 GLU B 232 5 ? 5 
HELX_P HELX_P10 AB1 ALA B 242 ? PHE B 247 ? ALA B 241 PHE B 246 1 ? 6 
HELX_P HELX_P11 AB2 THR C 29  ? TYR C 33  ? THR C 28  TYR C 32  5 ? 5 
HELX_P HELX_P12 AB3 ALA C 65  ? LYS C 68  ? ALA C 64  LYS C 67  5 ? 4 
HELX_P HELX_P13 AB4 ASP C 77  ? ASN C 79  ? ASP C 76  ASN C 78  5 ? 3 
HELX_P HELX_P14 AB5 THR C 90  ? THR C 94  ? THR C 89  THR C 93  5 ? 5 
HELX_P HELX_P15 AB6 GLN C 229 ? GLU C 233 ? GLN C 228 GLU C 232 5 ? 5 
HELX_P HELX_P16 AB7 ALA C 242 ? PHE C 247 ? ALA C 241 PHE C 246 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 23  SG ? ? ? 1_555 A CYS 99  SG ? ? A CYS 22  A CYS 98  1_555 ? ? ? ? ? ? ? 2.040 ? ? 
disulf2 disulf ? ? A CYS 170 SG ? ? ? 1_555 A CYS 238 SG ? ? A CYS 169 A CYS 237 1_555 ? ? ? ? ? ? ? 2.037 ? ? 
disulf3 disulf ? ? B CYS 23  SG ? ? ? 1_555 B CYS 99  SG ? ? B CYS 22  B CYS 98  1_555 ? ? ? ? ? ? ? 2.047 ? ? 
disulf4 disulf ? ? B CYS 170 SG ? ? ? 1_555 B CYS 238 SG ? ? B CYS 169 B CYS 237 1_555 ? ? ? ? ? ? ? 2.042 ? ? 
disulf5 disulf ? ? C CYS 23  SG ? ? ? 1_555 C CYS 99  SG ? ? C CYS 22  C CYS 98  1_555 ? ? ? ? ? ? ? 2.049 ? ? 
disulf6 disulf ? ? C CYS 170 SG ? ? ? 1_555 C CYS 238 SG ? ? C CYS 169 C CYS 237 1_555 ? ? ? ? ? ? ? 2.047 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 23  ? CYS A 99  ? CYS A 22  ? 1_555 CYS A 98  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 170 ? CYS A 238 ? CYS A 169 ? 1_555 CYS A 237 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 23  ? CYS B 99  ? CYS B 22  ? 1_555 CYS B 98  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 170 ? CYS B 238 ? CYS B 169 ? 1_555 CYS B 237 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS C 23  ? CYS C 99  ? CYS C 22  ? 1_555 CYS C 98  ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS C 170 ? CYS C 238 ? CYS C 169 ? 1_555 CYS C 237 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 5 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 5 ? 
AB2 ? 4 ? 
AB3 ? 3 ? 
AB4 ? 4 ? 
AB5 ? 6 ? 
AB6 ? 4 ? 
AB7 ? 5 ? 
AB8 ? 4 ? 
AB9 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB5 5 6 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB7 4 5 ? anti-parallel 
AB8 1 2 ? parallel      
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 4   ? SER A 8   ? GLN A 3   SER A 7   
AA1 2 LEU A 19  ? SER A 26  ? LEU A 18  SER A 25  
AA1 3 ILE A 81  ? MET A 86  ? ILE A 80  MET A 85  
AA1 4 PHE A 71  ? ASP A 76  ? PHE A 70  ASP A 75  
AA2 1 LEU A 12  ? VAL A 13  ? LEU A 11  VAL A 12  
AA2 2 THR A 122 ? VAL A 126 ? THR A 121 VAL A 125 
AA2 3 ALA A 95  ? ASP A 102 ? ALA A 94  ASP A 101 
AA2 4 MET A 35  ? LEU A 40  ? MET A 34  LEU A 39  
AA2 5 LEU A 46  ? ILE A 52  ? LEU A 45  ILE A 51  
AA2 6 GLN A 62  ? TYR A 63  ? GLN A 61  TYR A 62  
AA3 1 LEU A 12  ? VAL A 13  ? LEU A 11  VAL A 12  
AA3 2 THR A 122 ? VAL A 126 ? THR A 121 VAL A 125 
AA3 3 ALA A 95  ? ASP A 102 ? ALA A 94  ASP A 101 
AA3 4 PHE A 115 ? ASP A 116 ? PHE A 114 ASP A 115 
AA4 1 SER A 157 ? SER A 159 ? SER A 156 SER A 158 
AA4 2 THR A 254 ? THR A 257 ? THR A 253 THR A 256 
AA4 3 ASP A 235 ? TYR A 241 ? ASP A 234 TYR A 240 
AA4 4 VAL A 183 ? HIS A 188 ? VAL A 182 HIS A 187 
AA4 5 LYS A 195 ? ILE A 198 ? LYS A 194 ILE A 197 
AA5 1 SER A 157 ? SER A 159 ? SER A 156 SER A 158 
AA5 2 THR A 254 ? THR A 257 ? THR A 253 THR A 256 
AA5 3 ASP A 235 ? TYR A 241 ? ASP A 234 TYR A 240 
AA5 4 TYR A 248 ? PHE A 250 ? TYR A 247 PHE A 249 
AA6 1 VAL A 166 ? THR A 171 ? VAL A 165 THR A 170 
AA6 2 MET A 220 ? VAL A 225 ? MET A 219 VAL A 224 
AA6 3 PHE A 212 ? SER A 217 ? PHE A 211 SER A 216 
AA7 1 GLN B 4   ? SER B 8   ? GLN B 3   SER B 7   
AA7 2 LEU B 19  ? SER B 26  ? LEU B 18  SER B 25  
AA7 3 ILE B 81  ? MET B 86  ? ILE B 80  MET B 85  
AA7 4 PHE B 71  ? ASP B 76  ? PHE B 70  ASP B 75  
AA8 1 GLY B 11  ? VAL B 13  ? GLY B 10  VAL B 12  
AA8 2 THR B 122 ? VAL B 126 ? THR B 121 VAL B 125 
AA8 3 ALA B 95  ? ASP B 102 ? ALA B 94  ASP B 101 
AA8 4 MET B 35  ? LEU B 40  ? MET B 34  LEU B 39  
AA8 5 LEU B 46  ? ILE B 52  ? LEU B 45  ILE B 51  
AA8 6 GLN B 62  ? TYR B 63  ? GLN B 61  TYR B 62  
AA9 1 GLY B 11  ? VAL B 13  ? GLY B 10  VAL B 12  
AA9 2 THR B 122 ? VAL B 126 ? THR B 121 VAL B 125 
AA9 3 ALA B 95  ? ASP B 102 ? ALA B 94  ASP B 101 
AA9 4 PHE B 115 ? ASP B 116 ? PHE B 114 ASP B 115 
AB1 1 SER B 157 ? GLY B 160 ? SER B 156 GLY B 159 
AB1 2 THR B 254 ? VAL B 258 ? THR B 253 VAL B 257 
AB1 3 ALA B 234 ? TYR B 241 ? ALA B 233 TYR B 240 
AB1 4 VAL B 183 ? HIS B 188 ? VAL B 182 HIS B 187 
AB1 5 LYS B 195 ? ILE B 198 ? LYS B 194 ILE B 197 
AB2 1 SER B 157 ? GLY B 160 ? SER B 156 GLY B 159 
AB2 2 THR B 254 ? VAL B 258 ? THR B 253 VAL B 257 
AB2 3 ALA B 234 ? TYR B 241 ? ALA B 233 TYR B 240 
AB2 4 TYR B 248 ? PHE B 250 ? TYR B 247 PHE B 249 
AB3 1 VAL B 166 ? THR B 171 ? VAL B 165 THR B 170 
AB3 2 MET B 220 ? VAL B 225 ? MET B 219 VAL B 224 
AB3 3 PHE B 212 ? SER B 217 ? PHE B 211 SER B 216 
AB4 1 GLN C 4   ? SER C 8   ? GLN C 3   SER C 7   
AB4 2 LEU C 19  ? SER C 26  ? LEU C 18  SER C 25  
AB4 3 ILE C 81  ? MET C 86  ? ILE C 80  MET C 85  
AB4 4 PHE C 71  ? ASP C 76  ? PHE C 70  ASP C 75  
AB5 1 LEU C 12  ? VAL C 13  ? LEU C 11  VAL C 12  
AB5 2 THR C 122 ? VAL C 126 ? THR C 121 VAL C 125 
AB5 3 ALA C 95  ? ASP C 102 ? ALA C 94  ASP C 101 
AB5 4 MET C 35  ? LEU C 40  ? MET C 34  LEU C 39  
AB5 5 LEU C 46  ? ILE C 52  ? LEU C 45  ILE C 51  
AB5 6 GLN C 62  ? TYR C 63  ? GLN C 61  TYR C 62  
AB6 1 LEU C 12  ? VAL C 13  ? LEU C 11  VAL C 12  
AB6 2 THR C 122 ? VAL C 126 ? THR C 121 VAL C 125 
AB6 3 ALA C 95  ? ASP C 102 ? ALA C 94  ASP C 101 
AB6 4 PHE C 115 ? ASP C 116 ? PHE C 114 ASP C 115 
AB7 1 SER C 157 ? GLY C 160 ? SER C 156 GLY C 159 
AB7 2 THR C 254 ? VAL C 258 ? THR C 253 VAL C 257 
AB7 3 ASP C 235 ? TYR C 241 ? ASP C 234 TYR C 240 
AB7 4 VAL C 183 ? HIS C 188 ? VAL C 182 HIS C 187 
AB7 5 LYS C 195 ? ILE C 198 ? LYS C 194 ILE C 197 
AB8 1 SER C 157 ? GLY C 160 ? SER C 156 GLY C 159 
AB8 2 THR C 254 ? VAL C 258 ? THR C 253 VAL C 257 
AB8 3 ASP C 235 ? TYR C 241 ? ASP C 234 TYR C 240 
AB8 4 TYR C 248 ? PHE C 250 ? TYR C 247 PHE C 249 
AB9 1 VAL C 166 ? THR C 171 ? VAL C 165 THR C 170 
AB9 2 MET C 220 ? VAL C 225 ? MET C 219 VAL C 224 
AB9 3 PHE C 212 ? SER C 217 ? PHE C 211 SER C 216 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 4   ? N GLN A 3   O SER A 26  ? O SER A 25  
AA1 2 3 N LEU A 21  ? N LEU A 20  O LEU A 84  ? O LEU A 83  
AA1 3 4 O TYR A 83  ? O TYR A 82  N SER A 74  ? N SER A 73  
AA2 1 2 N VAL A 13  ? N VAL A 12  O THR A 125 ? O THR A 124 
AA2 2 3 O VAL A 124 ? O VAL A 123 N ALA A 95  ? N ALA A 94  
AA2 3 4 O ILE A 96  ? O ILE A 95  N LEU A 40  ? N LEU A 39  
AA2 4 5 N TRP A 37  ? N TRP A 36  O VAL A 49  ? O VAL A 48  
AA2 5 6 N LEU A 51  ? N LEU A 50  O GLN A 62  ? O GLN A 61  
AA3 1 2 N VAL A 13  ? N VAL A 12  O THR A 125 ? O THR A 124 
AA3 2 3 O VAL A 124 ? O VAL A 123 N ALA A 95  ? N ALA A 94  
AA3 3 4 N ARG A 101 ? N ARG A 100 O ASP A 116 ? O ASP A 115 
AA4 1 2 N ALA A 158 ? N ALA A 157 O LYS A 255 ? O LYS A 254 
AA4 2 3 O THR A 254 ? O THR A 253 N TYR A 236 ? N TYR A 235 
AA4 3 4 O TYR A 237 ? O TYR A 236 N TYR A 186 ? N TYR A 185 
AA4 4 5 N TRP A 185 ? N TRP A 184 O MET A 197 ? O MET A 196 
AA5 1 2 N ALA A 158 ? N ALA A 157 O LYS A 255 ? O LYS A 254 
AA5 2 3 O THR A 254 ? O THR A 253 N TYR A 236 ? N TYR A 235 
AA5 3 4 N SER A 240 ? N SER A 239 O VAL A 249 ? O VAL A 248 
AA6 1 2 N ILE A 168 ? N ILE A 167 O LEU A 223 ? O LEU A 222 
AA6 2 3 O SER A 222 ? O SER A 221 N SER A 215 ? N SER A 214 
AA7 1 2 N GLN B 4   ? N GLN B 3   O SER B 26  ? O SER B 25  
AA7 2 3 N LEU B 21  ? N LEU B 20  O LEU B 84  ? O LEU B 83  
AA7 3 4 O TYR B 83  ? O TYR B 82  N SER B 74  ? N SER B 73  
AA8 1 2 N VAL B 13  ? N VAL B 12  O THR B 125 ? O THR B 124 
AA8 2 3 O VAL B 124 ? O VAL B 123 N ALA B 95  ? N ALA B 94  
AA8 3 4 O TYR B 98  ? O TYR B 97  N PHE B 38  ? N PHE B 37  
AA8 4 5 N MET B 35  ? N MET B 34  O ILE B 52  ? O ILE B 51  
AA8 5 6 N LEU B 51  ? N LEU B 50  O GLN B 62  ? O GLN B 61  
AA9 1 2 N VAL B 13  ? N VAL B 12  O THR B 125 ? O THR B 124 
AA9 2 3 O VAL B 124 ? O VAL B 123 N ALA B 95  ? N ALA B 94  
AA9 3 4 N ARG B 101 ? N ARG B 100 O ASP B 116 ? O ASP B 115 
AB1 1 2 N ALA B 158 ? N ALA B 157 O THR B 257 ? O THR B 256 
AB1 2 3 O VAL B 256 ? O VAL B 255 N ALA B 234 ? N ALA B 233 
AB1 3 4 O ASP B 235 ? O ASP B 234 N HIS B 188 ? N HIS B 187 
AB1 4 5 N TRP B 185 ? N TRP B 184 O MET B 197 ? O MET B 196 
AB2 1 2 N ALA B 158 ? N ALA B 157 O THR B 257 ? O THR B 256 
AB2 2 3 O VAL B 256 ? O VAL B 255 N ALA B 234 ? N ALA B 233 
AB2 3 4 N SER B 240 ? N SER B 239 O VAL B 249 ? O VAL B 248 
AB3 1 2 N CYS B 170 ? N CYS B 169 O ALA B 221 ? O ALA B 220 
AB3 2 3 O THR B 224 ? O THR B 223 N SER B 213 ? N SER B 212 
AB4 1 2 N VAL C 6   ? N VAL C 5   O SER C 24  ? O SER C 23  
AB4 2 3 N LEU C 19  ? N LEU C 18  O MET C 86  ? O MET C 85  
AB4 3 4 O TYR C 83  ? O TYR C 82  N SER C 74  ? N SER C 73  
AB5 1 2 N VAL C 13  ? N VAL C 12  O THR C 125 ? O THR C 124 
AB5 2 3 O VAL C 124 ? O VAL C 123 N ALA C 95  ? N ALA C 94  
AB5 3 4 O TYR C 98  ? O TYR C 97  N PHE C 38  ? N PHE C 37  
AB5 4 5 N TRP C 37  ? N TRP C 36  O VAL C 49  ? O VAL C 48  
AB5 5 6 N LEU C 51  ? N LEU C 50  O GLN C 62  ? O GLN C 61  
AB6 1 2 N VAL C 13  ? N VAL C 12  O THR C 125 ? O THR C 124 
AB6 2 3 O VAL C 124 ? O VAL C 123 N ALA C 95  ? N ALA C 94  
AB6 3 4 N ARG C 101 ? N ARG C 100 O ASP C 116 ? O ASP C 115 
AB7 1 2 N ALA C 158 ? N ALA C 157 O LYS C 255 ? O LYS C 254 
AB7 2 3 O THR C 254 ? O THR C 253 N TYR C 236 ? N TYR C 235 
AB7 3 4 O ASP C 235 ? O ASP C 234 N HIS C 188 ? N HIS C 187 
AB7 4 5 N TRP C 185 ? N TRP C 184 O MET C 197 ? O MET C 196 
AB8 1 2 N ALA C 158 ? N ALA C 157 O LYS C 255 ? O LYS C 254 
AB8 2 3 O THR C 254 ? O THR C 253 N TYR C 236 ? N TYR C 235 
AB8 3 4 N SER C 240 ? N SER C 239 O VAL C 249 ? O VAL C 248 
AB9 1 2 N CYS C 170 ? N CYS C 169 O ALA C 221 ? O ALA C 220 
AB9 2 3 O SER C 222 ? O SER C 221 N SER C 215 ? N SER C 214 
# 
_pdbx_entry_details.entry_id                   9D7Y 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 O   A GLY 206 ? ? O  A HOH 401 ? ? 1.90 
2  1 O   A ALA 192 ? ? O  A HOH 402 ? ? 1.92 
3  1 O   C GLY 44  ? ? O  C HOH 401 ? ? 1.93 
4  1 O   A PHE 109 ? ? O  A HOH 403 ? ? 1.96 
5  1 OE2 C GLU 199 ? ? O  C HOH 402 ? ? 2.00 
6  1 O   B PHE 105 ? ? O  B HOH 401 ? ? 2.01 
7  1 O   A VAL 5   ? ? O  A HOH 404 ? ? 2.01 
8  1 ND2 C ASN 251 ? ? O  C HOH 403 ? ? 2.04 
9  1 O   C TRP 106 ? ? O  C HOH 404 ? ? 2.04 
10 1 O3  A SO4 302 ? ? O  A HOH 405 ? ? 2.05 
11 1 O   A HOH 405 ? ? O  A HOH 417 ? ? 2.05 
12 1 O   C GLY 30  ? ? OG C SER 53  ? ? 2.06 
13 1 OG  A SER 65  ? ? O  A HOH 406 ? ? 2.06 
14 1 O   A HOH 409 ? ? O  A HOH 416 ? ? 2.06 
15 1 O   C HOH 428 ? ? O  C HOH 445 ? ? 2.07 
16 1 OG  C SER 164 ? ? O  C HOH 405 ? ? 2.09 
17 1 OD1 B ASP 57  ? ? O  B HOH 402 ? ? 2.09 
18 1 O   A GLY 250 ? ? O  A HOH 407 ? ? 2.09 
19 1 NH2 B ARG 100 ? ? O  B HOH 403 ? ? 2.10 
20 1 O   A HOH 418 ? ? O  A HOH 447 ? ? 2.10 
21 1 O   B HOH 403 ? ? O  B HOH 416 ? ? 2.11 
22 1 O   B GLY 44  ? ? O  B HOH 404 ? ? 2.12 
23 1 O   A ARG 112 ? ? OH A TYR 247 ? ? 2.12 
24 1 NE2 A HIS 187 ? ? O  A HOH 408 ? ? 2.13 
25 1 O   A HOH 444 ? ? O  A HOH 448 ? ? 2.14 
26 1 O   A HOH 446 ? ? O  A HOH 453 ? ? 2.15 
27 1 N   B ALA 241 ? ? O  B PHE 246 ? ? 2.15 
28 1 O   C HOH 415 ? ? O  C HOH 429 ? ? 2.16 
29 1 O   B GLU 1   ? ? O  B HOH 405 ? ? 2.16 
30 1 N   C ALA 40  ? ? O  C HOH 401 ? ? 2.17 
31 1 ND2 A ASN 251 ? ? O  A HOH 409 ? ? 2.17 
32 1 OE2 C GLU 230 ? ? O  C HOH 406 ? ? 2.18 
33 1 OH  B TYR 97  ? ? O  B HOH 406 ? ? 2.18 
34 1 O   A HOH 452 ? ? O  A HOH 456 ? ? 2.18 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O A HOH 434 ? ? 1_555 O   B HOH 414 ? ? 3_646 2.08 
2 1 N A ASP 209 ? ? 1_555 OD2 C ASP 209 ? ? 2_664 2.09 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CG A ARG 16  ? ? CD A ARG 16  ? ? NE  A ARG 16  ? ? 96.71  111.80 -15.09 2.10 N 
2 1 CB C ASP 209 ? ? CG C ASP 209 ? ? OD2 C ASP 209 ? ? 111.93 118.30 -6.37  0.90 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 1   ? ? 103.75  146.94  
2  1 ALA A 55  ? ? -73.77  20.36   
3  1 ILE A 56  ? ? -140.28 -49.25  
4  1 ASP A 57  ? ? -178.00 -58.35  
5  1 ASP A 175 ? ? -140.25 -93.25  
6  1 VAL A 200 ? ? 73.63   -51.07  
7  1 ASP A 209 ? ? -56.21  -4.52   
8  1 LEU A 227 ? ? -47.23  162.09  
9  1 PHE A 246 ? ? 62.42   -91.77  
10 1 PRO B 14  ? ? -13.57  -124.93 
11 1 ILE B 56  ? ? -146.11 -49.97  
12 1 ASP B 57  ? ? 40.89   -142.25 
13 1 THR B 59  ? ? 76.69   134.03  
14 1 ALA B 64  ? ? -29.23  -59.83  
15 1 LYS B 67  ? ? -73.85  -112.25 
16 1 GLU B 91  ? ? -69.84  0.09    
17 1 TYR B 103 ? ? 88.59   140.58  
18 1 GLN B 119 ? ? -148.95 -24.15  
19 1 SER B 126 ? ? -64.53  -105.79 
20 1 ASP B 175 ? ? -139.79 -99.75  
21 1 VAL B 200 ? ? 73.50   -55.04  
22 1 ASP B 209 ? ? -59.93  -4.57   
23 1 LEU B 227 ? ? -49.64  165.51  
24 1 PHE B 246 ? ? 59.19   -91.34  
25 1 VAL C 2   ? ? 90.14   85.14   
26 1 ILE C 56  ? ? -145.56 -52.90  
27 1 ASP C 57  ? ? 30.32   -116.76 
28 1 GLU C 91  ? ? -69.50  2.78    
29 1 SER C 149 ? ? -176.14 86.64   
30 1 ALA C 150 ? ? 179.88  173.63  
31 1 ASP C 175 ? ? -134.20 -101.57 
32 1 VAL C 200 ? ? 72.85   -52.25  
33 1 ASP C 209 ? ? -53.18  -8.27   
34 1 PHE C 246 ? ? 51.62   -92.29  
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    GLU 
_pdbx_validate_planes.auth_asym_id    C 
_pdbx_validate_planes.auth_seq_id     6 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.072 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       457 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   7.93 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A SER 128 ? A SER 129 
2  1 Y 1 A GLY 129 ? A GLY 130 
3  1 Y 1 A GLY 130 ? A GLY 131 
4  1 Y 1 A GLY 131 ? A GLY 132 
5  1 Y 1 A GLY 132 ? A GLY 133 
6  1 Y 1 A SER 133 ? A SER 134 
7  1 Y 1 A GLY 134 ? A GLY 135 
8  1 Y 1 A GLY 135 ? A GLY 136 
9  1 Y 1 A GLY 136 ? A GLY 137 
10 1 Y 1 A GLY 137 ? A GLY 138 
11 1 Y 1 A SER 138 ? A SER 139 
12 1 Y 1 A GLY 139 ? A GLY 140 
13 1 Y 1 A GLY 140 ? A GLY 141 
14 1 Y 1 A GLY 141 ? A GLY 142 
15 1 Y 1 A GLY 142 ? A GLY 143 
16 1 Y 1 A SER 143 ? A SER 144 
17 1 Y 1 A GLY 144 ? A GLY 145 
18 1 Y 1 A GLY 145 ? A GLY 146 
19 1 Y 1 A GLY 146 ? A GLY 147 
20 1 Y 1 A GLY 147 ? A GLY 148 
21 1 Y 1 A GLN 148 ? A GLN 149 
22 1 Y 1 A SER 149 ? A SER 150 
23 1 Y 1 A LEU 258 ? A LEU 259 
24 1 Y 1 A GLY 259 ? A GLY 260 
25 1 Y 1 A HIS 260 ? A HIS 261 
26 1 Y 1 A HIS 261 ? A HIS 262 
27 1 Y 1 A HIS 262 ? A HIS 263 
28 1 Y 1 A HIS 263 ? A HIS 264 
29 1 Y 1 A HIS 264 ? A HIS 265 
30 1 Y 1 B ASP 0   ? B ASP 1   
31 1 Y 1 B SER 128 ? B SER 129 
32 1 Y 1 B GLY 129 ? B GLY 130 
33 1 Y 1 B GLY 130 ? B GLY 131 
34 1 Y 1 B GLY 131 ? B GLY 132 
35 1 Y 1 B GLY 132 ? B GLY 133 
36 1 Y 1 B SER 133 ? B SER 134 
37 1 Y 1 B GLY 134 ? B GLY 135 
38 1 Y 1 B GLY 135 ? B GLY 136 
39 1 Y 1 B GLY 136 ? B GLY 137 
40 1 Y 1 B GLY 137 ? B GLY 138 
41 1 Y 1 B SER 138 ? B SER 139 
42 1 Y 1 B GLY 139 ? B GLY 140 
43 1 Y 1 B GLY 140 ? B GLY 141 
44 1 Y 1 B GLY 141 ? B GLY 142 
45 1 Y 1 B GLY 142 ? B GLY 143 
46 1 Y 1 B SER 143 ? B SER 144 
47 1 Y 1 B GLY 144 ? B GLY 145 
48 1 Y 1 B GLY 145 ? B GLY 146 
49 1 Y 1 B GLY 146 ? B GLY 147 
50 1 Y 1 B GLY 147 ? B GLY 148 
51 1 Y 1 B GLN 148 ? B GLN 149 
52 1 Y 1 B SER 149 ? B SER 150 
53 1 Y 1 B HIS 260 ? B HIS 261 
54 1 Y 1 B HIS 261 ? B HIS 262 
55 1 Y 1 B HIS 262 ? B HIS 263 
56 1 Y 1 B HIS 263 ? B HIS 264 
57 1 Y 1 B HIS 264 ? B HIS 265 
58 1 Y 1 C ASP 0   ? C ASP 1   
59 1 Y 1 C SER 128 ? C SER 129 
60 1 Y 1 C GLY 129 ? C GLY 130 
61 1 Y 1 C GLY 130 ? C GLY 131 
62 1 Y 1 C GLY 131 ? C GLY 132 
63 1 Y 1 C GLY 132 ? C GLY 133 
64 1 Y 1 C SER 133 ? C SER 134 
65 1 Y 1 C GLY 134 ? C GLY 135 
66 1 Y 1 C GLY 135 ? C GLY 136 
67 1 Y 1 C GLY 136 ? C GLY 137 
68 1 Y 1 C GLY 137 ? C GLY 138 
69 1 Y 1 C SER 138 ? C SER 139 
70 1 Y 1 C GLY 139 ? C GLY 140 
71 1 Y 1 C GLY 140 ? C GLY 141 
72 1 Y 1 C GLY 141 ? C GLY 142 
73 1 Y 1 C GLY 142 ? C GLY 143 
74 1 Y 1 C SER 143 ? C SER 144 
75 1 Y 1 C GLY 144 ? C GLY 145 
76 1 Y 1 C GLY 145 ? C GLY 146 
77 1 Y 1 C GLY 146 ? C GLY 147 
78 1 Y 1 C GLY 147 ? C GLY 148 
79 1 Y 1 C GLY 259 ? C GLY 260 
80 1 Y 1 C HIS 260 ? C HIS 261 
81 1 Y 1 C HIS 261 ? C HIS 262 
82 1 Y 1 C HIS 262 ? C HIS 263 
83 1 Y 1 C HIS 263 ? C HIS 264 
84 1 Y 1 C HIS 264 ? C HIS 265 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
SO4 S    S N N 304 
SO4 O1   O N N 305 
SO4 O2   O N N 306 
SO4 O3   O N N 307 
SO4 O4   O N N 308 
THR N    N N N 309 
THR CA   C N S 310 
THR C    C N N 311 
THR O    O N N 312 
THR CB   C N R 313 
THR OG1  O N N 314 
THR CG2  C N N 315 
THR OXT  O N N 316 
THR H    H N N 317 
THR H2   H N N 318 
THR HA   H N N 319 
THR HB   H N N 320 
THR HG1  H N N 321 
THR HG21 H N N 322 
THR HG22 H N N 323 
THR HG23 H N N 324 
THR HXT  H N N 325 
TRP N    N N N 326 
TRP CA   C N S 327 
TRP C    C N N 328 
TRP O    O N N 329 
TRP CB   C N N 330 
TRP CG   C Y N 331 
TRP CD1  C Y N 332 
TRP CD2  C Y N 333 
TRP NE1  N Y N 334 
TRP CE2  C Y N 335 
TRP CE3  C Y N 336 
TRP CZ2  C Y N 337 
TRP CZ3  C Y N 338 
TRP CH2  C Y N 339 
TRP OXT  O N N 340 
TRP H    H N N 341 
TRP H2   H N N 342 
TRP HA   H N N 343 
TRP HB2  H N N 344 
TRP HB3  H N N 345 
TRP HD1  H N N 346 
TRP HE1  H N N 347 
TRP HE3  H N N 348 
TRP HZ2  H N N 349 
TRP HZ3  H N N 350 
TRP HH2  H N N 351 
TRP HXT  H N N 352 
TYR N    N N N 353 
TYR CA   C N S 354 
TYR C    C N N 355 
TYR O    O N N 356 
TYR CB   C N N 357 
TYR CG   C Y N 358 
TYR CD1  C Y N 359 
TYR CD2  C Y N 360 
TYR CE1  C Y N 361 
TYR CE2  C Y N 362 
TYR CZ   C Y N 363 
TYR OH   O N N 364 
TYR OXT  O N N 365 
TYR H    H N N 366 
TYR H2   H N N 367 
TYR HA   H N N 368 
TYR HB2  H N N 369 
TYR HB3  H N N 370 
TYR HD1  H N N 371 
TYR HD2  H N N 372 
TYR HE1  H N N 373 
TYR HE2  H N N 374 
TYR HH   H N N 375 
TYR HXT  H N N 376 
VAL N    N N N 377 
VAL CA   C N S 378 
VAL C    C N N 379 
VAL O    O N N 380 
VAL CB   C N N 381 
VAL CG1  C N N 382 
VAL CG2  C N N 383 
VAL OXT  O N N 384 
VAL H    H N N 385 
VAL H2   H N N 386 
VAL HA   H N N 387 
VAL HB   H N N 388 
VAL HG11 H N N 389 
VAL HG12 H N N 390 
VAL HG13 H N N 391 
VAL HG21 H N N 392 
VAL HG22 H N N 393 
VAL HG23 H N N 394 
VAL HXT  H N N 395 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
SO4 S   O1   doub N N 290 
SO4 S   O2   doub N N 291 
SO4 S   O3   sing N N 292 
SO4 S   O4   sing N N 293 
THR N   CA   sing N N 294 
THR N   H    sing N N 295 
THR N   H2   sing N N 296 
THR CA  C    sing N N 297 
THR CA  CB   sing N N 298 
THR CA  HA   sing N N 299 
THR C   O    doub N N 300 
THR C   OXT  sing N N 301 
THR CB  OG1  sing N N 302 
THR CB  CG2  sing N N 303 
THR CB  HB   sing N N 304 
THR OG1 HG1  sing N N 305 
THR CG2 HG21 sing N N 306 
THR CG2 HG22 sing N N 307 
THR CG2 HG23 sing N N 308 
THR OXT HXT  sing N N 309 
TRP N   CA   sing N N 310 
TRP N   H    sing N N 311 
TRP N   H2   sing N N 312 
TRP CA  C    sing N N 313 
TRP CA  CB   sing N N 314 
TRP CA  HA   sing N N 315 
TRP C   O    doub N N 316 
TRP C   OXT  sing N N 317 
TRP CB  CG   sing N N 318 
TRP CB  HB2  sing N N 319 
TRP CB  HB3  sing N N 320 
TRP CG  CD1  doub Y N 321 
TRP CG  CD2  sing Y N 322 
TRP CD1 NE1  sing Y N 323 
TRP CD1 HD1  sing N N 324 
TRP CD2 CE2  doub Y N 325 
TRP CD2 CE3  sing Y N 326 
TRP NE1 CE2  sing Y N 327 
TRP NE1 HE1  sing N N 328 
TRP CE2 CZ2  sing Y N 329 
TRP CE3 CZ3  doub Y N 330 
TRP CE3 HE3  sing N N 331 
TRP CZ2 CH2  doub Y N 332 
TRP CZ2 HZ2  sing N N 333 
TRP CZ3 CH2  sing Y N 334 
TRP CZ3 HZ3  sing N N 335 
TRP CH2 HH2  sing N N 336 
TRP OXT HXT  sing N N 337 
TYR N   CA   sing N N 338 
TYR N   H    sing N N 339 
TYR N   H2   sing N N 340 
TYR CA  C    sing N N 341 
TYR CA  CB   sing N N 342 
TYR CA  HA   sing N N 343 
TYR C   O    doub N N 344 
TYR C   OXT  sing N N 345 
TYR CB  CG   sing N N 346 
TYR CB  HB2  sing N N 347 
TYR CB  HB3  sing N N 348 
TYR CG  CD1  doub Y N 349 
TYR CG  CD2  sing Y N 350 
TYR CD1 CE1  sing Y N 351 
TYR CD1 HD1  sing N N 352 
TYR CD2 CE2  doub Y N 353 
TYR CD2 HD2  sing N N 354 
TYR CE1 CZ   doub Y N 355 
TYR CE1 HE1  sing N N 356 
TYR CE2 CZ   sing Y N 357 
TYR CE2 HE2  sing N N 358 
TYR CZ  OH   sing N N 359 
TYR OH  HH   sing N N 360 
TYR OXT HXT  sing N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_initial_refinement_model.id 
_pdbx_initial_refinement_model.entity_id_list 
_pdbx_initial_refinement_model.type 
_pdbx_initial_refinement_model.source_name 
_pdbx_initial_refinement_model.accession_code 
_pdbx_initial_refinement_model.details 
1 ? 'experimental model' PDB 6CBP ? 
2 ? 'experimental model' PDB 5U68 ? 
3 ? 'experimental model' PDB 5J74 ? 
4 ? 'experimental model' PDB 5J75 ? 
5 ? 'experimental model' PDB 5C6W ? 
6 ? 'experimental model' PDB 5U0U ? 
7 ? 'experimental model' PDB 4NIK ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9D7Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010358 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009619 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011753 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP A 1 1   ? 59.38245 25.25599 67.95932  1.000 58.77714 ? 0   ASP A N   1 
ATOM   2    C CA  . ASP A 1 1   ? 58.65525 25.75197 69.12590  1.000 56.68501 ? 0   ASP A CA  1 
ATOM   3    C C   . ASP A 1 1   ? 59.48760 26.77086 69.89855  1.000 52.18697 ? 0   ASP A C   1 
ATOM   4    O O   . ASP A 1 1   ? 59.20790 27.97807 69.84916  1.000 45.71320 ? 0   ASP A O   1 
ATOM   5    C CB  . ASP A 1 1   ? 58.26025 24.59657 70.05913  1.000 47.80775 ? 0   ASP A CB  1 
ATOM   6    C CG  . ASP A 1 1   ? 59.28409 23.47082 70.06692  1.000 44.68438 ? 0   ASP A CG  1 
ATOM   7    N N   . GLU A 1 2   ? 60.51607 26.23077 70.57044  1.000 52.38216 ? 1   GLU A N   1 
ATOM   8    C CA  . GLU A 1 2   ? 61.40002 26.84178 71.56834  1.000 46.01196 ? 1   GLU A CA  1 
ATOM   9    C C   . GLU A 1 2   ? 61.00947 26.36566 72.96111  1.000 44.24980 ? 1   GLU A C   1 
ATOM   10   O O   . GLU A 1 2   ? 59.83891 26.05789 73.21859  1.000 42.47500 ? 1   GLU A O   1 
ATOM   11   C CB  . GLU A 1 2   ? 61.39735 28.37350 71.53525  1.000 38.56637 ? 1   GLU A CB  1 
ATOM   12   N N   . VAL A 1 3   ? 62.00161 26.23463 73.83784  1.000 38.88164 ? 2   VAL A N   1 
ATOM   13   C CA  . VAL A 1 3   ? 61.76752 25.90666 75.23994  1.000 34.76137 ? 2   VAL A CA  1 
ATOM   14   C C   . VAL A 1 3   ? 61.21102 27.13214 75.95406  1.000 39.55281 ? 2   VAL A C   1 
ATOM   15   O O   . VAL A 1 3   ? 61.85962 28.18360 75.97558  1.000 48.62565 ? 2   VAL A O   1 
ATOM   16   C CB  . VAL A 1 3   ? 63.06704 25.43807 75.90407  1.000 37.46539 ? 2   VAL A CB  1 
ATOM   17   C CG1 . VAL A 1 3   ? 62.78566 24.87600 77.30370  1.000 37.82517 ? 2   VAL A CG1 1 
ATOM   18   C CG2 . VAL A 1 3   ? 63.79966 24.42243 75.01447  1.000 33.29322 ? 2   VAL A CG2 1 
ATOM   19   N N   . GLN A 1 4   ? 60.01259 27.02153 76.54098  1.000 34.55743 ? 3   GLN A N   1 
ATOM   20   C CA  . GLN A 1 4   ? 59.49301 28.13445 77.33777  1.000 38.63071 ? 3   GLN A CA  1 
ATOM   21   C C   . GLN A 1 4   ? 58.95151 27.64423 78.67546  1.000 41.87363 ? 3   GLN A C   1 
ATOM   22   O O   . GLN A 1 4   ? 58.17700 26.68091 78.72931  1.000 39.58284 ? 3   GLN A O   1 
ATOM   23   C CB  . GLN A 1 4   ? 58.41567 28.93439 76.57170  1.000 47.35864 ? 3   GLN A CB  1 
ATOM   24   C CG  . GLN A 1 4   ? 57.55761 29.91494 77.42561  1.000 45.21744 ? 3   GLN A CG  1 
ATOM   25   C CD  . GLN A 1 4   ? 57.33216 31.28446 76.73528  1.000 44.43232 ? 3   GLN A CD  1 
ATOM   26   O OE1 . GLN A 1 4   ? 58.18568 31.75915 75.98696  1.000 48.68154 ? 3   GLN A OE1 1 
ATOM   27   N NE2 . GLN A 1 4   ? 56.18222 31.90480 76.98219  1.000 38.35799 ? 3   GLN A NE2 1 
ATOM   28   N N   . LEU A 1 5   ? 59.33685 28.33695 79.74780  1.000 42.30557 ? 4   LEU A N   1 
ATOM   29   C CA  . LEU A 1 5   ? 58.84942 28.07450 81.09440  1.000 32.37819 ? 4   LEU A CA  1 
ATOM   30   C C   . LEU A 1 5   ? 58.14645 29.32637 81.60107  1.000 30.81209 ? 4   LEU A C   1 
ATOM   31   O O   . LEU A 1 5   ? 58.73985 30.40830 81.60480  1.000 29.66673 ? 4   LEU A O   1 
ATOM   32   C CB  . LEU A 1 5   ? 59.99888 27.68946 82.02676  1.000 31.06327 ? 4   LEU A CB  1 
ATOM   33   C CG  . LEU A 1 5   ? 60.83819 26.43627 81.73268  1.000 35.36907 ? 4   LEU A CG  1 
ATOM   34   C CD1 . LEU A 1 5   ? 61.76094 26.11885 82.88213  1.000 33.15293 ? 4   LEU A CD1 1 
ATOM   35   C CD2 . LEU A 1 5   ? 59.98319 25.23487 81.46215  1.000 37.50688 ? 4   LEU A CD2 1 
ATOM   36   N N   . VAL A 1 6   ? 56.89570 29.17380 82.04126  1.000 26.68798 ? 5   VAL A N   1 
ATOM   37   C CA  . VAL A 1 6   ? 56.07533 30.26787 82.56275  1.000 26.03513 ? 5   VAL A CA  1 
ATOM   38   C C   . VAL A 1 6   ? 55.57884 29.93459 83.96616  1.000 31.96890 ? 5   VAL A C   1 
ATOM   39   O O   . VAL A 1 6   ? 54.74560 29.03384 84.14100  1.000 32.97820 ? 5   VAL A O   1 
ATOM   40   C CB  . VAL A 1 6   ? 54.89966 30.58715 81.63922  1.000 30.35403 ? 5   VAL A CB  1 
ATOM   41   C CG1 . VAL A 1 6   ? 53.89528 31.46585 82.35928  1.000 24.32638 ? 5   VAL A CG1 1 
ATOM   42   C CG2 . VAL A 1 6   ? 55.42388 31.32271 80.44453  1.000 31.34624 ? 5   VAL A CG2 1 
ATOM   43   N N   . GLU A 1 7   ? 56.07010 30.68510 84.96233  1.000 30.58538 ? 6   GLU A N   1 
ATOM   44   C CA  . GLU A 1 7   ? 55.67410 30.55388 86.36194  1.000 24.57852 ? 6   GLU A CA  1 
ATOM   45   C C   . GLU A 1 7   ? 54.59163 31.56717 86.71617  1.000 29.90046 ? 6   GLU A C   1 
ATOM   46   O O   . GLU A 1 7   ? 54.67921 32.74560 86.34718  1.000 31.81366 ? 6   GLU A O   1 
ATOM   47   C CB  . GLU A 1 7   ? 56.85905 30.75280 87.30696  1.000 24.46590 ? 6   GLU A CB  1 
ATOM   48   C CG  . GLU A 1 7   ? 58.16337 30.15665 86.83072  1.000 28.44169 ? 6   GLU A CG  1 
ATOM   49   C CD  . GLU A 1 7   ? 59.06110 31.15944 86.11419  1.000 32.74942 ? 6   GLU A CD  1 
ATOM   50   O OE1 . GLU A 1 7   ? 58.56411 31.97055 85.28550  1.000 29.31526 ? 6   GLU A OE1 1 
ATOM   51   O OE2 . GLU A 1 7   ? 60.27930 31.13639 86.39317  1.000 33.06847 ? 6   GLU A OE2 1 
ATOM   52   N N   . SER A 1 8   ? 53.57016 31.10384 87.43397  1.000 25.18407 ? 7   SER A N   1 
ATOM   53   C CA  . SER A 1 8   ? 52.43891 31.93777 87.79832  1.000 24.05346 ? 7   SER A CA  1 
ATOM   54   C C   . SER A 1 8   ? 52.05703 31.67367 89.24593  1.000 27.53184 ? 7   SER A C   1 
ATOM   55   O O   . SER A 1 8   ? 52.55593 30.74275 89.88417  1.000 27.65497 ? 7   SER A O   1 
ATOM   56   C CB  . SER A 1 8   ? 51.24486 31.68891 86.88115  1.000 23.44521 ? 7   SER A CB  1 
ATOM   57   O OG  . SER A 1 8   ? 51.04009 30.30732 86.71076  1.000 36.71509 ? 7   SER A OG  1 
ATOM   58   N N   . GLY A 1 9   ? 51.15679 32.51180 89.75987  1.000 24.90806 ? 8   GLY A N   1 
ATOM   59   C CA  . GLY A 1 9   ? 50.58029 32.34827 91.07566  1.000 22.24246 ? 8   GLY A CA  1 
ATOM   60   C C   . GLY A 1 9   ? 51.02312 33.33546 92.13358  1.000 25.34784 ? 8   GLY A C   1 
ATOM   61   O O   . GLY A 1 9   ? 50.28615 33.53040 93.10228  1.000 30.88652 ? 8   GLY A O   1 
ATOM   62   N N   . GLY A 1 10  ? 52.16691 33.98895 91.97939  1.000 28.90808 ? 9   GLY A N   1 
ATOM   63   C CA  . GLY A 1 10  ? 52.64379 34.90391 93.00546  1.000 30.11066 ? 9   GLY A CA  1 
ATOM   64   C C   . GLY A 1 10  ? 51.74800 36.13073 93.21274  1.000 30.85864 ? 9   GLY A C   1 
ATOM   65   O O   . GLY A 1 10  ? 50.80586 36.38832 92.46444  1.000 30.66311 ? 9   GLY A O   1 
ATOM   66   N N   . GLY A 1 11  ? 52.06506 36.90232 94.24898  1.000 31.33465 ? 10  GLY A N   1 
ATOM   67   C CA  . GLY A 1 11  ? 51.27481 38.06168 94.62802  1.000 33.83919 ? 10  GLY A CA  1 
ATOM   68   C C   . GLY A 1 11  ? 51.50013 38.44291 96.07932  1.000 28.34175 ? 10  GLY A C   1 
ATOM   69   O O   . GLY A 1 11  ? 52.27079 37.81075 96.79762  1.000 28.44863 ? 10  GLY A O   1 
ATOM   70   N N   . LEU A 1 12  ? 50.80486 39.49730 96.50454  1.000 23.83042 ? 11  LEU A N   1 
ATOM   71   C CA  . LEU A 1 12  ? 50.91333 39.94153 97.89444  1.000 29.86225 ? 11  LEU A CA  1 
ATOM   72   C C   . LEU A 1 12  ? 50.05764 39.03443 98.75318  1.000 26.91121 ? 11  LEU A C   1 
ATOM   73   O O   . LEU A 1 12  ? 48.85829 38.91519 98.50351  1.000 32.63753 ? 11  LEU A O   1 
ATOM   74   C CB  . LEU A 1 12  ? 50.42032 41.37553 98.06993  1.000 34.65201 ? 11  LEU A CB  1 
ATOM   75   C CG  . LEU A 1 12  ? 50.56047 41.94155 99.50168  1.000 32.74651 ? 11  LEU A CG  1 
ATOM   76   C CD1 . LEU A 1 12  ? 51.99717 42.22972 99.90209  1.000 26.75666 ? 11  LEU A CD1 1 
ATOM   77   C CD2 . LEU A 1 12  ? 49.65964 43.11536 99.81124  1.000 32.19899 ? 11  LEU A CD2 1 
ATOM   78   N N   . VAL A 1 13  ? 50.65562 38.38653 99.74761  1.000 29.14569 ? 12  VAL A N   1 
ATOM   79   C CA  . VAL A 1 13  ? 49.93950 37.43019 100.58665 1.000 29.62196 ? 12  VAL A CA  1 
ATOM   80   C C   . VAL A 1 13  ? 50.24725 37.69875 102.04757 1.000 31.93964 ? 12  VAL A C   1 
ATOM   81   O O   . VAL A 1 13  ? 51.36590 38.07915 102.39971 1.000 33.12537 ? 12  VAL A O   1 
ATOM   82   C CB  . VAL A 1 13  ? 50.27481 35.97028 100.21312 1.000 25.63384 ? 12  VAL A CB  1 
ATOM   83   C CG1 . VAL A 1 13  ? 49.95287 35.74461 98.76168  1.000 23.28493 ? 12  VAL A CG1 1 
ATOM   84   C CG2 . VAL A 1 13  ? 51.73113 35.65800 100.46712 1.000 22.34209 ? 12  VAL A CG2 1 
ATOM   85   N N   . GLN A 1 14  ? 49.25110 37.49929 102.90783 1.000 34.04640 ? 13  GLN A N   1 
ATOM   86   C CA  . GLN A 1 14  ? 49.49199 37.65298 104.34621 1.000 38.55275 ? 13  GLN A CA  1 
ATOM   87   C C   . GLN A 1 14  ? 50.35329 36.52670 104.90754 1.000 32.82059 ? 13  GLN A C   1 
ATOM   88   O O   . GLN A 1 14  ? 50.50589 35.47235 104.29039 1.000 35.18836 ? 13  GLN A O   1 
ATOM   89   C CB  . GLN A 1 14  ? 48.17225 37.78939 105.10025 1.000 35.88439 ? 13  GLN A CB  1 
ATOM   90   C CG  . GLN A 1 14  ? 47.73101 39.22625 105.28916 1.000 35.91475 ? 13  GLN A CG  1 
ATOM   91   C CD  . GLN A 1 14  ? 47.53862 40.00406 104.01081 1.000 49.38226 ? 13  GLN A CD  1 
ATOM   92   O OE1 . GLN A 1 14  ? 48.18285 41.04421 103.82358 1.000 51.44476 ? 13  GLN A OE1 1 
ATOM   93   N NE2 . GLN A 1 14  ? 46.69274 39.49700 103.10123 1.000 52.23541 ? 13  GLN A NE2 1 
ATOM   94   N N   . PRO A 1 15  ? 51.01370 36.77958 106.03062 1.000 36.18376 ? 14  PRO A N   1 
ATOM   95   C CA  . PRO A 1 15  ? 51.96154 35.79698 106.55949 1.000 35.76543 ? 14  PRO A CA  1 
ATOM   96   C C   . PRO A 1 15  ? 51.27907 34.51310 107.03025 1.000 33.55171 ? 14  PRO A C   1 
ATOM   97   O O   . PRO A 1 15  ? 50.06041 34.42537 107.18755 1.000 31.03544 ? 14  PRO A O   1 
ATOM   98   C CB  . PRO A 1 15  ? 52.62219 36.54883 107.72409 1.000 30.54147 ? 14  PRO A CB  1 
ATOM   99   C CG  . PRO A 1 15  ? 52.49594 38.00605 107.34442 1.000 31.60258 ? 14  PRO A CG  1 
ATOM   100  C CD  . PRO A 1 15  ? 51.16534 38.10220 106.67574 1.000 34.64368 ? 14  PRO A CD  1 
ATOM   101  N N   . GLY A 1 16  ? 52.10099 33.48145 107.20623 1.000 35.29474 ? 15  GLY A N   1 
ATOM   102  C CA  . GLY A 1 16  ? 51.65406 32.15940 107.62285 1.000 34.69917 ? 15  GLY A CA  1 
ATOM   103  C C   . GLY A 1 16  ? 50.70561 31.45607 106.67061 1.000 32.67047 ? 15  GLY A C   1 
ATOM   104  O O   . GLY A 1 16  ? 50.19652 30.36358 106.94477 1.000 38.14472 ? 15  GLY A O   1 
ATOM   105  N N   . ARG A 1 17  ? 50.49873 32.06486 105.51969 1.000 31.52424 ? 16  ARG A N   1 
ATOM   106  C CA  . ARG A 1 17  ? 49.53409 31.59372 104.54899 1.000 33.55537 ? 16  ARG A CA  1 
ATOM   107  C C   . ARG A 1 17  ? 50.13384 30.50892 103.62128 1.000 32.40350 ? 16  ARG A C   1 
ATOM   108  O O   . ARG A 1 17  ? 51.34669 30.30890 103.58034 1.000 34.17350 ? 16  ARG A O   1 
ATOM   109  C CB  . ARG A 1 17  ? 49.03764 32.81193 103.77700 1.000 31.04251 ? 16  ARG A CB  1 
ATOM   110  C CG  . ARG A 1 17  ? 47.99014 32.41031 102.92742 1.000 39.30894 ? 16  ARG A CG  1 
ATOM   111  C CD  . ARG A 1 17  ? 47.47752 33.41733 102.03769 1.000 36.28255 ? 16  ARG A CD  1 
ATOM   112  N NE  . ARG A 1 17  ? 46.84220 32.50909 101.10166 1.000 36.29434 ? 16  ARG A NE  1 
ATOM   113  C CZ  . ARG A 1 17  ? 46.26560 32.86200 99.97387  1.000 37.41123 ? 16  ARG A CZ  1 
ATOM   114  N NH1 . ARG A 1 17  ? 46.23655 34.13194 99.60549  1.000 44.06561 ? 16  ARG A NH1 1 
ATOM   115  N NH2 . ARG A 1 17  ? 45.76132 31.92730 99.19499  1.000 36.84583 ? 16  ARG A NH2 1 
ATOM   116  N N   . SER A 1 18  ? 49.27638 29.82851 102.84200 1.000 26.23668 ? 17  SER A N   1 
ATOM   117  C CA  . SER A 1 18  ? 49.69566 28.82915 101.85759 1.000 26.95595 ? 17  SER A CA  1 
ATOM   118  C C   . SER A 1 18  ? 49.38966 29.30597 100.44674 1.000 30.05099 ? 17  SER A C   1 
ATOM   119  O O   . SER A 1 18  ? 48.31956 29.86705 100.19603 1.000 32.89150 ? 17  SER A O   1 
ATOM   120  C CB  . SER A 1 18  ? 48.99879 27.47968 102.05278 1.000 27.38817 ? 17  SER A CB  1 
ATOM   121  O OG  . SER A 1 18  ? 49.66002 26.69614 103.01832 1.000 28.38642 ? 17  SER A OG  1 
ATOM   122  N N   . LEU A 1 19  ? 50.31825 29.03334 99.52442  1.000 26.00767 ? 18  LEU A N   1 
ATOM   123  C CA  . LEU A 1 19  ? 50.26243 29.48610 98.13790  1.000 27.67927 ? 18  LEU A CA  1 
ATOM   124  C C   . LEU A 1 19  ? 50.87835 28.42450 97.23198  1.000 29.91839 ? 18  LEU A C   1 
ATOM   125  O O   . LEU A 1 19  ? 51.90929 27.84101 97.58146  1.000 30.53818 ? 18  LEU A O   1 
ATOM   126  C CB  . LEU A 1 19  ? 51.01730 30.80838 97.98889  1.000 28.33806 ? 18  LEU A CB  1 
ATOM   127  C CG  . LEU A 1 19  ? 50.80754 31.70182 96.77565  1.000 24.87818 ? 18  LEU A CG  1 
ATOM   128  C CD1 . LEU A 1 19  ? 49.48299 32.43297 96.86836  1.000 25.64516 ? 18  LEU A CD1 1 
ATOM   129  C CD2 . LEU A 1 19  ? 51.95707 32.69861 96.72397  1.000 32.15170 ? 18  LEU A CD2 1 
ATOM   130  N N   . ARG A 1 20  ? 50.27756 28.19175 96.06217  1.000 27.97473 ? 19  ARG A N   1 
ATOM   131  C CA  . ARG A 1 20  ? 50.83284 27.25136 95.09200  1.000 22.76398 ? 19  ARG A CA  1 
ATOM   132  C C   . ARG A 1 20  ? 51.29254 27.99421 93.85370  1.000 23.12498 ? 19  ARG A C   1 
ATOM   133  O O   . ARG A 1 20  ? 50.49208 28.67534 93.21036  1.000 25.16419 ? 19  ARG A O   1 
ATOM   134  C CB  . ARG A 1 20  ? 49.84041 26.16604 94.67781  1.000 18.53092 ? 19  ARG A CB  1 
ATOM   135  C CG  . ARG A 1 20  ? 50.52452 25.11725 93.78127  1.000 25.13652 ? 19  ARG A CG  1 
ATOM   136  C CD  . ARG A 1 20  ? 49.58896 24.03677 93.22687  1.000 25.97997 ? 19  ARG A CD  1 
ATOM   137  N NE  . ARG A 1 20  ? 48.56633 24.56168 92.32050  1.000 33.55434 ? 19  ARG A NE  1 
ATOM   138  C CZ  . ARG A 1 20  ? 47.87980 23.82481 91.44430  1.000 37.41753 ? 19  ARG A CZ  1 
ATOM   139  N NH1 . ARG A 1 20  ? 48.09799 22.51313 91.34000  1.000 32.49891 ? 19  ARG A NH1 1 
ATOM   140  N NH2 . ARG A 1 20  ? 46.96381 24.39965 90.66879  1.000 36.73084 ? 19  ARG A NH2 1 
ATOM   141  N N   . LEU A 1 21  ? 52.58255 27.86272 93.53695  1.000 25.28703 ? 20  LEU A N   1 
ATOM   142  C CA  . LEU A 1 21  ? 53.16433 28.39912 92.31740  1.000 22.96969 ? 20  LEU A CA  1 
ATOM   143  C C   . LEU A 1 21  ? 53.13650 27.33225 91.24330  1.000 26.85216 ? 20  LEU A C   1 
ATOM   144  O O   . LEU A 1 21  ? 53.46349 26.17207 91.50339  1.000 30.25741 ? 20  LEU A O   1 
ATOM   145  C CB  . LEU A 1 21  ? 54.60753 28.84247 92.55777  1.000 25.41629 ? 20  LEU A CB  1 
ATOM   146  C CG  . LEU A 1 21  ? 54.74426 30.00054 93.56543  1.000 31.13267 ? 20  LEU A CG  1 
ATOM   147  C CD1 . LEU A 1 21  ? 56.10037 30.66507 93.47437  1.000 28.69684 ? 20  LEU A CD1 1 
ATOM   148  C CD2 . LEU A 1 21  ? 53.62358 31.03877 93.41881  1.000 25.34362 ? 20  LEU A CD2 1 
ATOM   149  N N   . SER A 1 22  ? 52.76641 27.73373 90.03091  1.000 30.76832 ? 21  SER A N   1 
ATOM   150  C CA  . SER A 1 22  ? 52.72815 26.84185 88.87931  1.000 30.49121 ? 21  SER A CA  1 
ATOM   151  C C   . SER A 1 22  ? 53.84644 27.18169 87.91012  1.000 29.88154 ? 21  SER A C   1 
ATOM   152  O O   . SER A 1 22  ? 54.21745 28.34173 87.75359  1.000 33.01806 ? 21  SER A O   1 
ATOM   153  C CB  . SER A 1 22  ? 51.38642 26.92307 88.14250  1.000 29.42482 ? 21  SER A CB  1 
ATOM   154  O OG  . SER A 1 22  ? 50.36478 26.20200 88.81512  1.000 35.54917 ? 21  SER A OG  1 
ATOM   155  N N   . CYS A 1 23  ? 54.35972 26.16348 87.23464  1.000 29.99805 ? 22  CYS A N   1 
ATOM   156  C CA  . CYS A 1 23  ? 55.32182 26.35382 86.15954  1.000 30.13052 ? 22  CYS A CA  1 
ATOM   157  C C   . CYS A 1 23  ? 54.89775 25.49094 84.97588  1.000 34.82348 ? 22  CYS A C   1 
ATOM   158  O O   . CYS A 1 23  ? 54.93089 24.25709 85.06049  1.000 35.77325 ? 22  CYS A O   1 
ATOM   159  C CB  . CYS A 1 23  ? 56.72134 25.99962 86.63773  1.000 33.58829 ? 22  CYS A CB  1 
ATOM   160  S SG  . CYS A 1 23  ? 57.91103 25.79935 85.33807  1.000 46.57282 ? 22  CYS A SG  1 
ATOM   161  N N   . SER A 1 24  ? 54.51720 26.12898 83.86909  1.000 28.09190 ? 23  SER A N   1 
ATOM   162  C CA  . SER A 1 24  ? 54.03601 25.41866 82.69197  1.000 28.79118 ? 23  SER A CA  1 
ATOM   163  C C   . SER A 1 24  ? 55.12275 25.40489 81.62952  1.000 29.94764 ? 23  SER A C   1 
ATOM   164  O O   . SER A 1 24  ? 55.46954 26.44961 81.06975  1.000 36.03255 ? 23  SER A O   1 
ATOM   165  C CB  . SER A 1 24  ? 52.76346 26.05810 82.15363  1.000 30.80236 ? 23  SER A CB  1 
ATOM   166  O OG  . SER A 1 24  ? 51.80446 26.15628 83.19028  1.000 36.45926 ? 23  SER A OG  1 
ATOM   167  N N   . ALA A 1 25  ? 55.59762 24.21546 81.30158  1.000 35.33012 ? 24  ALA A N   1 
ATOM   168  C CA  . ALA A 1 25  ? 56.67489 24.06143 80.34145  1.000 36.43054 ? 24  ALA A CA  1 
ATOM   169  C C   . ALA A 1 25  ? 56.11962 23.91913 78.93317  1.000 28.64222 ? 24  ALA A C   1 
ATOM   170  O O   . ALA A 1 25  ? 54.93080 23.67727 78.73083  1.000 27.27765 ? 24  ALA A O   1 
ATOM   171  C CB  . ALA A 1 25  ? 57.52972 22.84447 80.69015  1.000 30.22907 ? 24  ALA A CB  1 
ATOM   172  N N   . SER A 1 26  ? 57.00433 24.09677 77.95677  1.000 28.86545 ? 25  SER A N   1 
ATOM   173  C CA  . SER A 1 26  ? 56.66043 23.95399 76.55155  1.000 35.15840 ? 25  SER A CA  1 
ATOM   174  C C   . SER A 1 26  ? 57.92839 23.91179 75.72047  1.000 37.60496 ? 25  SER A C   1 
ATOM   175  O O   . SER A 1 26  ? 58.87736 24.64608 76.00095  1.000 39.37017 ? 25  SER A O   1 
ATOM   176  C CB  . SER A 1 26  ? 55.79025 25.12816 76.08535  1.000 39.88059 ? 25  SER A CB  1 
ATOM   177  O OG  . SER A 1 26  ? 55.88257 25.30890 74.68675  1.000 43.10344 ? 25  SER A OG  1 
ATOM   178  N N   . GLY A 1 27  ? 57.92924 23.06557 74.69043  1.000 41.87034 ? 26  GLY A N   1 
ATOM   179  C CA  . GLY A 1 27  ? 58.99284 23.05295 73.70675  1.000 40.79036 ? 26  GLY A CA  1 
ATOM   180  C C   . GLY A 1 27  ? 59.95450 21.89848 73.80686  1.000 41.76216 ? 26  GLY A C   1 
ATOM   181  O O   . GLY A 1 27  ? 60.83664 21.77893 72.94742  1.000 45.91767 ? 26  GLY A O   1 
ATOM   182  N N   . PHE A 1 28  ? 59.81260 21.04486 74.81783  1.000 40.56193 ? 27  PHE A N   1 
ATOM   183  C CA  . PHE A 1 28  ? 60.65366 19.87193 75.00531  1.000 30.44580 ? 27  PHE A CA  1 
ATOM   184  C C   . PHE A 1 28  ? 59.77992 18.80362 75.62469  1.000 33.47949 ? 27  PHE A C   1 
ATOM   185  O O   . PHE A 1 28  ? 58.68037 19.08004 76.10316  1.000 37.35439 ? 27  PHE A O   1 
ATOM   186  C CB  . PHE A 1 28  ? 61.85119 20.15366 75.91585  1.000 34.31157 ? 27  PHE A CB  1 
ATOM   187  C CG  . PHE A 1 28  ? 61.46176 20.54083 77.32618  1.000 32.09363 ? 27  PHE A CG  1 
ATOM   188  C CD1 . PHE A 1 28  ? 61.16535 21.85597 77.64413  1.000 37.34760 ? 27  PHE A CD1 1 
ATOM   189  C CD2 . PHE A 1 28  ? 61.38428 19.59558 78.32602  1.000 29.53529 ? 27  PHE A CD2 1 
ATOM   190  C CE1 . PHE A 1 28  ? 60.80173 22.21510 78.94272  1.000 35.71409 ? 27  PHE A CE1 1 
ATOM   191  C CE2 . PHE A 1 28  ? 61.02770 19.94832 79.61518  1.000 33.55506 ? 27  PHE A CE2 1 
ATOM   192  C CZ  . PHE A 1 28  ? 60.73351 21.25361 79.92637  1.000 29.88522 ? 27  PHE A CZ  1 
ATOM   193  N N   . THR A 1 29  ? 60.29273 17.58371 75.65521  1.000 31.74887 ? 28  THR A N   1 
ATOM   194  C CA  . THR A 1 29  ? 59.50143 16.45000 76.11464  1.000 31.80101 ? 28  THR A CA  1 
ATOM   195  C C   . THR A 1 29  ? 59.59057 16.36526 77.63972  1.000 32.87198 ? 28  THR A C   1 
ATOM   196  O O   . THR A 1 29  ? 60.45268 15.69556 78.21203  1.000 31.78213 ? 28  THR A O   1 
ATOM   197  C CB  . THR A 1 29  ? 59.95405 15.20619 75.36597  1.000 37.92262 ? 28  THR A CB  1 
ATOM   198  O OG1 . THR A 1 29  ? 59.39407 14.03940 75.98257  1.000 41.89564 ? 28  THR A OG1 1 
ATOM   199  C CG2 . THR A 1 29  ? 61.49593 15.16381 75.21268  1.000 33.00625 ? 28  THR A CG2 1 
ATOM   200  N N   . PHE A 1 30  ? 58.61325 17.01248 78.28482  1.000 32.69779 ? 29  PHE A N   1 
ATOM   201  C CA  . PHE A 1 30  ? 58.69224 17.41696 79.68884  1.000 30.54062 ? 29  PHE A CA  1 
ATOM   202  C C   . PHE A 1 30  ? 59.19769 16.31489 80.59385  1.000 32.45192 ? 29  PHE A C   1 
ATOM   203  O O   . PHE A 1 30  ? 60.00442 16.56712 81.49305  1.000 30.34754 ? 29  PHE A O   1 
ATOM   204  C CB  . PHE A 1 30  ? 57.30934 17.88877 80.16273  1.000 37.51713 ? 29  PHE A CB  1 
ATOM   205  C CG  . PHE A 1 30  ? 57.29192 18.42824 81.57120  1.000 35.56517 ? 29  PHE A CG  1 
ATOM   206  C CD1 . PHE A 1 30  ? 57.89109 19.63458 81.87403  1.000 35.97025 ? 29  PHE A CD1 1 
ATOM   207  C CD2 . PHE A 1 30  ? 56.66895 17.72976 82.58939  1.000 39.73875 ? 29  PHE A CD2 1 
ATOM   208  C CE1 . PHE A 1 30  ? 57.88025 20.12905 83.17156  1.000 37.46800 ? 29  PHE A CE1 1 
ATOM   209  C CE2 . PHE A 1 30  ? 56.64526 18.22170 83.88707  1.000 36.47592 ? 29  PHE A CE2 1 
ATOM   210  C CZ  . PHE A 1 30  ? 57.25499 19.41928 84.17650  1.000 36.86349 ? 29  PHE A CZ  1 
ATOM   211  N N   . GLY A 1 31  ? 58.72686 15.08662 80.36973  1.000 39.37600 ? 30  GLY A N   1 
ATOM   212  C CA  . GLY A 1 31  ? 58.91748 13.95507 81.26331  1.000 28.86977 ? 30  GLY A CA  1 
ATOM   213  C C   . GLY A 1 31  ? 60.34930 13.51663 81.43475  1.000 24.06154 ? 30  GLY A C   1 
ATOM   214  O O   . GLY A 1 31  ? 60.62664 12.73197 82.34572  1.000 29.98142 ? 30  GLY A O   1 
ATOM   215  N N   . ASP A 1 32  ? 61.25318 13.96394 80.57294  1.000 25.02478 ? 31  ASP A N   1 
ATOM   216  C CA  . ASP A 1 32  ? 62.62996 13.49490 80.56477  1.000 25.03615 ? 31  ASP A CA  1 
ATOM   217  C C   . ASP A 1 32  ? 63.60527 14.39162 81.32259  1.000 29.54542 ? 31  ASP A C   1 
ATOM   218  O O   . ASP A 1 32  ? 64.81445 14.17346 81.22809  1.000 26.98745 ? 31  ASP A O   1 
ATOM   219  C CB  . ASP A 1 32  ? 63.08413 13.32092 79.12950  1.000 26.19654 ? 31  ASP A CB  1 
ATOM   220  C CG  . ASP A 1 32  ? 62.18343 12.36985 78.36050  1.000 34.59960 ? 31  ASP A CG  1 
ATOM   221  O OD1 . ASP A 1 32  ? 61.64733 11.41753 78.96438  1.000 32.36506 ? 31  ASP A OD1 1 
ATOM   222  O OD2 . ASP A 1 32  ? 61.98478 12.58856 77.15127  1.000 40.40548 ? 31  ASP A OD2 1 
ATOM   223  N N   . TYR A 1 33  ? 63.12157 15.40990 82.04724  1.000 36.84726 ? 32  TYR A N   1 
ATOM   224  C CA  . TYR A 1 33  ? 63.98380 16.44168 82.62435  1.000 30.99979 ? 32  TYR A CA  1 
ATOM   225  C C   . TYR A 1 33  ? 63.69003 16.72017 84.09671  1.000 32.10131 ? 32  TYR A C   1 
ATOM   226  O O   . TYR A 1 33  ? 62.52791 16.82599 84.50678  1.000 32.77260 ? 32  TYR A O   1 
ATOM   227  C CB  . TYR A 1 33  ? 63.86082 17.75453 81.86684  1.000 27.25745 ? 32  TYR A CB  1 
ATOM   228  C CG  . TYR A 1 33  ? 64.39572 17.69316 80.47161  1.000 29.31730 ? 32  TYR A CG  1 
ATOM   229  C CD1 . TYR A 1 33  ? 63.54977 17.39169 79.41000  1.000 31.28562 ? 32  TYR A CD1 1 
ATOM   230  C CD2 . TYR A 1 33  ? 65.74183 17.92654 80.20223  1.000 24.54250 ? 32  TYR A CD2 1 
ATOM   231  C CE1 . TYR A 1 33  ? 64.02460 17.33235 78.10627  1.000 27.40845 ? 32  TYR A CE1 1 
ATOM   232  C CE2 . TYR A 1 33  ? 66.22956 17.87190 78.90407  1.000 25.60449 ? 32  TYR A CE2 1 
ATOM   233  C CZ  . TYR A 1 33  ? 65.36240 17.57649 77.85428  1.000 27.14605 ? 32  TYR A CZ  1 
ATOM   234  O OH  . TYR A 1 33  ? 65.81042 17.52321 76.54111  1.000 32.29368 ? 32  TYR A OH  1 
ATOM   235  N N   . ALA A 1 34  ? 64.75576 16.81673 84.89434  1.000 27.34428 ? 33  ALA A N   1 
ATOM   236  C CA  . ALA A 1 34  ? 64.60917 17.37847 86.22260  1.000 22.72199 ? 33  ALA A CA  1 
ATOM   237  C C   . ALA A 1 34  ? 64.11812 18.80569 86.09000  1.000 28.72278 ? 33  ALA A C   1 
ATOM   238  O O   . ALA A 1 34  ? 64.38281 19.49279 85.10358  1.000 31.09407 ? 33  ALA A O   1 
ATOM   239  C CB  . ALA A 1 34  ? 65.93148 17.35474 86.99270  1.000 21.34037 ? 33  ALA A CB  1 
ATOM   240  N N   . MET A 1 35  ? 63.41916 19.25446 87.10148  1.000 32.47747 ? 34  MET A N   1 
ATOM   241  C CA  . MET A 1 35  ? 62.93361 20.61124 87.16129  1.000 27.21666 ? 34  MET A CA  1 
ATOM   242  C C   . MET A 1 35  ? 63.29901 21.10520 88.54606  1.000 29.33876 ? 34  MET A C   1 
ATOM   243  O O   . MET A 1 35  ? 63.16368 20.37765 89.53417  1.000 32.53726 ? 34  MET A O   1 
ATOM   244  C CB  . MET A 1 35  ? 61.41922 20.65929 86.88203  1.000 27.71746 ? 34  MET A CB  1 
ATOM   245  C CG  . MET A 1 35  ? 61.03111 20.19784 85.45594  1.000 36.69982 ? 34  MET A CG  1 
ATOM   246  S SD  . MET A 1 35  ? 61.58674 21.27701 84.11409  1.000 36.45753 ? 34  MET A SD  1 
ATOM   247  C CE  . MET A 1 35  ? 60.43437 22.62803 84.32530  1.000 28.44577 ? 34  MET A CE  1 
ATOM   248  N N   . SER A 1 36  ? 63.80515 22.32198 88.60284  1.000 30.99631 ? 35  SER A N   1 
ATOM   249  C CA  . SER A 1 36  ? 64.30869 22.89760 89.83337  1.000 29.05111 ? 35  SER A CA  1 
ATOM   250  C C   . SER A 1 36  ? 63.67748 24.26351 90.07159  1.000 34.24853 ? 35  SER A C   1 
ATOM   251  O O   . SER A 1 36  ? 63.48611 25.05803 89.13630  1.000 32.55199 ? 35  SER A O   1 
ATOM   252  C CB  . SER A 1 36  ? 65.82065 23.02421 89.76633  1.000 28.61843 ? 35  SER A CB  1 
ATOM   253  O OG  . SER A 1 36  ? 66.37338 23.33592 91.01823  1.000 32.56085 ? 35  SER A OG  1 
ATOM   254  N N   . TRP A 1 37  ? 63.37257 24.53169 91.34044  1.000 34.10058 ? 36  TRP A N   1 
ATOM   255  C CA  . TRP A 1 37  ? 62.84473 25.81611 91.76642  1.000 26.45519 ? 36  TRP A CA  1 
ATOM   256  C C   . TRP A 1 37  ? 63.94831 26.60703 92.43889  1.000 26.39864 ? 36  TRP A C   1 
ATOM   257  O O   . TRP A 1 37  ? 64.60219 26.10488 93.35957  1.000 28.23523 ? 36  TRP A O   1 
ATOM   258  C CB  . TRP A 1 37  ? 61.68123 25.63287 92.72492  1.000 25.79196 ? 36  TRP A CB  1 
ATOM   259  C CG  . TRP A 1 37  ? 60.41065 25.32009 92.03325  1.000 30.10671 ? 36  TRP A CG  1 
ATOM   260  C CD1 . TRP A 1 37  ? 59.85559 24.08104 91.82922  1.000 29.38610 ? 36  TRP A CD1 1 
ATOM   261  C CD2 . TRP A 1 37  ? 59.50891 26.26285 91.45922  1.000 33.19707 ? 36  TRP A CD2 1 
ATOM   262  N NE1 . TRP A 1 37  ? 58.65828 24.20173 91.15931  1.000 30.42903 ? 36  TRP A NE1 1 
ATOM   263  C CE2 . TRP A 1 37  ? 58.42427 25.53359 90.91987  1.000 36.35545 ? 36  TRP A CE2 1 
ATOM   264  C CE3 . TRP A 1 37  ? 59.51552 27.65449 91.33837  1.000 28.05774 ? 36  TRP A CE3 1 
ATOM   265  C CZ2 . TRP A 1 37  ? 57.36030 26.15768 90.27370  1.000 34.75699 ? 36  TRP A CZ2 1 
ATOM   266  C CZ3 . TRP A 1 37  ? 58.46347 28.26338 90.71118  1.000 29.99444 ? 36  TRP A CZ3 1 
ATOM   267  C CH2 . TRP A 1 37  ? 57.39608 27.52083 90.18640  1.000 34.22649 ? 36  TRP A CH2 1 
ATOM   268  N N   . PHE A 1 38  ? 64.11400 27.85561 92.00811  1.000 26.27347 ? 37  PHE A N   1 
ATOM   269  C CA  . PHE A 1 38  ? 65.08837 28.77675 92.56384  1.000 25.09342 ? 37  PHE A CA  1 
ATOM   270  C C   . PHE A 1 38  ? 64.37195 30.02289 93.04913  1.000 29.45915 ? 37  PHE A C   1 
ATOM   271  O O   . PHE A 1 38  ? 63.25365 30.32459 92.62584  1.000 30.33081 ? 37  PHE A O   1 
ATOM   272  C CB  . PHE A 1 38  ? 66.14184 29.17388 91.54245  1.000 26.24289 ? 37  PHE A CB  1 
ATOM   273  C CG  . PHE A 1 38  ? 66.99433 28.04697 91.08989  1.000 28.86236 ? 37  PHE A CG  1 
ATOM   274  C CD1 . PHE A 1 38  ? 66.61077 27.26522 90.00686  1.000 30.09759 ? 37  PHE A CD1 1 
ATOM   275  C CD2 . PHE A 1 38  ? 68.19515 27.76844 91.73108  1.000 29.53055 ? 37  PHE A CD2 1 
ATOM   276  C CE1 . PHE A 1 38  ? 67.40740 26.21163 89.57525  1.000 28.55141 ? 37  PHE A CE1 1 
ATOM   277  C CE2 . PHE A 1 38  ? 68.99779 26.71604 91.30667  1.000 25.23265 ? 37  PHE A CE2 1 
ATOM   278  C CZ  . PHE A 1 38  ? 68.60334 25.93962 90.23118  1.000 27.25603 ? 37  PHE A CZ  1 
ATOM   279  N N   . ARG A 1 39  ? 65.04452 30.75861 93.93045  1.000 33.39616 ? 38  ARG A N   1 
ATOM   280  C CA  . ARG A 1 39  ? 64.49886 31.96344 94.54596  1.000 30.59095 ? 38  ARG A CA  1 
ATOM   281  C C   . ARG A 1 39  ? 65.51267 33.10767 94.54629  1.000 33.80621 ? 38  ARG A C   1 
ATOM   282  O O   . ARG A 1 39  ? 66.67098 32.91875 94.94180  1.000 34.63651 ? 38  ARG A O   1 
ATOM   283  C CB  . ARG A 1 39  ? 64.09234 31.63061 95.98291  1.000 29.72800 ? 38  ARG A CB  1 
ATOM   284  C CG  . ARG A 1 39  ? 63.68289 32.80829 96.70892  1.000 32.88087 ? 38  ARG A CG  1 
ATOM   285  C CD  . ARG A 1 39  ? 63.87036 32.78612 98.22382  1.000 42.69047 ? 38  ARG A CD  1 
ATOM   286  N NE  . ARG A 1 39  ? 63.30092 31.64623 98.93075  1.000 42.33503 ? 38  ARG A NE  1 
ATOM   287  C CZ  . ARG A 1 39  ? 63.10924 31.65138 100.24726 1.000 42.02341 ? 38  ARG A CZ  1 
ATOM   288  N NH1 . ARG A 1 39  ? 63.44156 32.73796 100.93816 1.000 49.61711 ? 38  ARG A NH1 1 
ATOM   289  N NH2 . ARG A 1 39  ? 62.56827 30.61253 100.86920 1.000 27.88033 ? 38  ARG A NH2 1 
ATOM   290  N N   . LEU A 1 40  ? 65.07481 34.30011 94.13508  1.000 29.63737 ? 39  LEU A N   1 
ATOM   291  C CA  . LEU A 1 40  ? 65.87404 35.52033 94.25883  1.000 31.49220 ? 39  LEU A CA  1 
ATOM   292  C C   . LEU A 1 40  ? 65.18074 36.46501 95.23088  1.000 27.82929 ? 39  LEU A C   1 
ATOM   293  O O   . LEU A 1 40  ? 64.05559 36.90186 94.96917  1.000 23.16162 ? 39  LEU A O   1 
ATOM   294  C CB  . LEU A 1 40  ? 66.07787 36.21690 92.90763  1.000 31.67749 ? 39  LEU A CB  1 
ATOM   295  C CG  . LEU A 1 40  ? 66.74511 37.58571 93.07655  1.000 30.82071 ? 39  LEU A CG  1 
ATOM   296  C CD1 . LEU A 1 40  ? 68.19711 37.44360 93.51528  1.000 29.40652 ? 39  LEU A CD1 1 
ATOM   297  C CD2 . LEU A 1 40  ? 66.63473 38.46313 91.82550  1.000 32.50863 ? 39  LEU A CD2 1 
ATOM   298  N N   . ALA A 1 41  ? 65.82890 36.74035 96.36612  1.000 30.48060 ? 40  ALA A N   1 
ATOM   299  C CA  . ALA A 1 41  ? 65.24826 37.58700 97.40047  1.000 33.80251 ? 40  ALA A CA  1 
ATOM   300  C C   . ALA A 1 41  ? 66.13639 38.80091 97.65776  1.000 34.09433 ? 40  ALA A C   1 
ATOM   301  O O   . ALA A 1 41  ? 67.36338 38.68679 97.61710  1.000 38.79830 ? 40  ALA A O   1 
ATOM   302  C CB  . ALA A 1 41  ? 65.05637 36.80384 98.70721  1.000 29.41200 ? 40  ALA A CB  1 
ATOM   303  N N   . PRO A 1 42  ? 65.55475 39.95793 97.96752  1.000 29.06725 ? 41  PRO A N   1 
ATOM   304  C CA  . PRO A 1 42  ? 66.36666 41.17301 98.11829  1.000 32.39499 ? 41  PRO A CA  1 
ATOM   305  C C   . PRO A 1 42  ? 67.31212 41.05154 99.30338  1.000 35.26561 ? 41  PRO A C   1 
ATOM   306  O O   . PRO A 1 42  ? 66.93586 40.54578 100.36150 1.000 38.17671 ? 41  PRO A O   1 
ATOM   307  C CB  . PRO A 1 42  ? 65.32445 42.27123 98.33748  1.000 29.87262 ? 41  PRO A CB  1 
ATOM   308  C CG  . PRO A 1 42  ? 64.17752 41.57454 98.95060  1.000 29.88060 ? 41  PRO A CG  1 
ATOM   309  C CD  . PRO A 1 42  ? 64.17068 40.15695 98.42414  1.000 31.52049 ? 41  PRO A CD  1 
ATOM   310  N N   . GLY A 1 43  ? 68.54166 41.54082 99.13633  1.000 35.54211 ? 42  GLY A N   1 
ATOM   311  C CA  . GLY A 1 43  ? 69.52144 41.39601 100.19689 1.000 38.11998 ? 42  GLY A CA  1 
ATOM   312  C C   . GLY A 1 43  ? 70.23130 40.05561 100.10406 1.000 53.21291 ? 42  GLY A C   1 
ATOM   313  O O   . GLY A 1 43  ? 71.46861 40.01295 100.08516 1.000 62.11111 ? 42  GLY A O   1 
ATOM   314  N N   . LYS A 1 44  ? 69.47177 38.95095 100.10112 1.000 52.46927 ? 43  LYS A N   1 
ATOM   315  C CA  . LYS A 1 44  ? 70.06505 37.65329 99.81010  1.000 42.50799 ? 43  LYS A CA  1 
ATOM   316  C C   . LYS A 1 44  ? 70.43302 37.60216 98.33100  1.000 49.36332 ? 43  LYS A C   1 
ATOM   317  O O   . LYS A 1 44  ? 70.09124 38.49379 97.54788  1.000 55.85467 ? 43  LYS A O   1 
ATOM   318  C CB  . LYS A 1 44  ? 69.10727 36.49865 100.10534 1.000 36.17744 ? 43  LYS A CB  1 
ATOM   319  C CG  . LYS A 1 44  ? 68.96439 36.11626 101.56410 1.000 43.97393 ? 43  LYS A CG  1 
ATOM   320  C CD  . LYS A 1 44  ? 67.93966 36.96424 102.32099 1.000 48.69269 ? 43  LYS A CD  1 
ATOM   321  C CE  . LYS A 1 44  ? 66.53100 36.56133 101.87306 1.000 48.97354 ? 43  LYS A CE  1 
ATOM   322  N NZ  . LYS A 1 44  ? 65.39084 37.16930 102.62120 1.000 47.30657 ? 43  LYS A NZ  1 
ATOM   323  N N   . GLY A 1 45  ? 71.08526 36.52543 97.92202  1.000 43.11048 ? 44  GLY A N   1 
ATOM   324  C CA  . GLY A 1 45  ? 71.36331 36.40004 96.50478  1.000 40.49264 ? 44  GLY A CA  1 
ATOM   325  C C   . GLY A 1 45  ? 70.35152 35.52741 95.80269  1.000 35.17809 ? 44  GLY A C   1 
ATOM   326  O O   . GLY A 1 45  ? 69.14057 35.72014 95.94527  1.000 33.64125 ? 44  GLY A O   1 
ATOM   327  N N   . LEU A 1 46  ? 70.84753 34.60433 94.98887  1.000 34.04185 ? 45  LEU A N   1 
ATOM   328  C CA  . LEU A 1 46  ? 70.02185 33.53403 94.46226  1.000 34.72780 ? 45  LEU A CA  1 
ATOM   329  C C   . LEU A 1 46  ? 70.11286 32.35078 95.42068  1.000 35.97337 ? 45  LEU A C   1 
ATOM   330  O O   . LEU A 1 46  ? 71.13390 32.13632 96.07684  1.000 37.85504 ? 45  LEU A O   1 
ATOM   331  C CB  . LEU A 1 46  ? 70.46953 33.12905 93.06270  1.000 28.13249 ? 45  LEU A CB  1 
ATOM   332  C CG  . LEU A 1 46  ? 69.95578 34.02818 91.95226  1.000 26.96813 ? 45  LEU A CG  1 
ATOM   333  C CD1 . LEU A 1 46  ? 70.63550 33.69732 90.64637  1.000 29.20541 ? 45  LEU A CD1 1 
ATOM   334  C CD2 . LEU A 1 46  ? 68.47430 33.83848 91.82211  1.000 32.25025 ? 45  LEU A CD2 1 
ATOM   335  N N   . GLU A 1 47  ? 69.03396 31.58559 95.50294  1.000 37.46361 ? 46  GLU A N   1 
ATOM   336  C CA  . GLU A 1 47  ? 68.97002 30.42914 96.38309  1.000 35.92221 ? 46  GLU A CA  1 
ATOM   337  C C   . GLU A 1 47  ? 68.31238 29.28435 95.63699  1.000 28.20528 ? 46  GLU A C   1 
ATOM   338  O O   . GLU A 1 47  ? 67.38660 29.49970 94.85525  1.000 28.58082 ? 46  GLU A O   1 
ATOM   339  C CB  . GLU A 1 47  ? 68.19015 30.76121 97.68282  1.000 39.61476 ? 46  GLU A CB  1 
ATOM   340  C CG  . GLU A 1 47  ? 68.40396 29.76105 98.83330  1.000 44.78635 ? 46  GLU A CG  1 
ATOM   341  C CD  . GLU A 1 47  ? 67.38715 29.89030 99.97828  1.000 54.16622 ? 46  GLU A CD  1 
ATOM   342  O OE1 . GLU A 1 47  ? 66.16501 30.00708 99.71239  1.000 58.00598 ? 46  GLU A OE1 1 
ATOM   343  O OE2 . GLU A 1 47  ? 67.81947 29.85300 101.15522 1.000 51.93332 ? 46  GLU A OE2 1 
ATOM   344  N N   . TRP A 1 48  ? 68.81701 28.07489 95.85064  1.000 38.79168 ? 47  TRP A N   1 
ATOM   345  C CA  . TRP A 1 48  ? 68.12896 26.86660 95.40707  1.000 29.97509 ? 47  TRP A CA  1 
ATOM   346  C C   . TRP A 1 48  ? 66.97914 26.54932 96.36144  1.000 32.48704 ? 47  TRP A C   1 
ATOM   347  O O   . TRP A 1 48  ? 67.14731 26.61466 97.58330  1.000 32.88986 ? 47  TRP A O   1 
ATOM   348  C CB  . TRP A 1 48  ? 69.11924 25.70534 95.34367  1.000 26.45851 ? 47  TRP A CB  1 
ATOM   349  C CG  . TRP A 1 48  ? 68.49390 24.38014 94.99851  1.000 32.41661 ? 47  TRP A CG  1 
ATOM   350  C CD1 . TRP A 1 48  ? 67.97285 23.99958 93.79285  1.000 28.51487 ? 47  TRP A CD1 1 
ATOM   351  C CD2 . TRP A 1 48  ? 68.31504 23.27518 95.87511  1.000 29.93295 ? 47  TRP A CD2 1 
ATOM   352  N NE1 . TRP A 1 48  ? 67.48815 22.72976 93.86968  1.000 24.57411 ? 47  TRP A NE1 1 
ATOM   353  C CE2 . TRP A 1 48  ? 67.68519 22.25754 95.13854  1.000 30.57094 ? 47  TRP A CE2 1 
ATOM   354  C CE3 . TRP A 1 48  ? 68.63584 23.04107 97.21508  1.000 35.19394 ? 47  TRP A CE3 1 
ATOM   355  C CZ2 . TRP A 1 48  ? 67.37067 21.02266 95.69548  1.000 32.54580 ? 47  TRP A CZ2 1 
ATOM   356  C CZ3 . TRP A 1 48  ? 68.31600 21.81559 97.77306  1.000 31.61197 ? 47  TRP A CZ3 1 
ATOM   357  C CH2 . TRP A 1 48  ? 67.69147 20.82300 97.01413  1.000 32.19356 ? 47  TRP A CH2 1 
ATOM   358  N N   . VAL A 1 49  ? 65.80734 26.21184 95.82170  1.000 24.57803 ? 48  VAL A N   1 
ATOM   359  C CA  . VAL A 1 49  ? 64.71006 25.86442 96.72098  1.000 24.79606 ? 48  VAL A CA  1 
ATOM   360  C C   . VAL A 1 49  ? 64.56256 24.35078 96.76407  1.000 29.49898 ? 48  VAL A C   1 
ATOM   361  O O   . VAL A 1 49  ? 64.64706 23.73447 97.83005  1.000 30.52808 ? 48  VAL A O   1 
ATOM   362  C CB  . VAL A 1 49  ? 63.37532 26.51342 96.30364  1.000 31.06684 ? 48  VAL A CB  1 
ATOM   363  C CG1 . VAL A 1 49  ? 62.23211 26.05610 97.23881  1.000 25.42746 ? 48  VAL A CG1 1 
ATOM   364  C CG2 . VAL A 1 49  ? 63.48307 28.02801 96.26547  1.000 28.27372 ? 48  VAL A CG2 1 
ATOM   365  N N   . GLY A 1 50  ? 64.35534 23.74351 95.60300  1.000 34.56584 ? 49  GLY A N   1 
ATOM   366  C CA  . GLY A 1 50  ? 64.16005 22.30981 95.53504  1.000 29.60244 ? 49  GLY A CA  1 
ATOM   367  C C   . GLY A 1 50  ? 64.25589 21.83115 94.10596  1.000 34.64118 ? 49  GLY A C   1 
ATOM   368  O O   . GLY A 1 50  ? 64.38048 22.62333 93.16467  1.000 29.50723 ? 49  GLY A O   1 
ATOM   369  N N   . LEU A 1 51  ? 64.16804 20.50555 93.96700  1.000 37.54637 ? 50  LEU A N   1 
ATOM   370  C CA  . LEU A 1 51  ? 64.41226 19.77903 92.72724  1.000 29.31893 ? 50  LEU A CA  1 
ATOM   371  C C   . LEU A 1 51  ? 63.47803 18.58233 92.65010  1.000 34.41725 ? 50  LEU A C   1 
ATOM   372  O O   . LEU A 1 51  ? 63.35105 17.84379 93.63156  1.000 37.97713 ? 50  LEU A O   1 
ATOM   373  C CB  . LEU A 1 51  ? 65.85791 19.28374 92.70847  1.000 32.32885 ? 50  LEU A CB  1 
ATOM   374  C CG  . LEU A 1 51  ? 66.38926 18.42458 91.57231  1.000 27.51024 ? 50  LEU A CG  1 
ATOM   375  C CD1 . LEU A 1 51  ? 66.66494 19.24499 90.32685  1.000 30.68212 ? 50  LEU A CD1 1 
ATOM   376  C CD2 . LEU A 1 51  ? 67.58882 17.61761 92.02393  1.000 32.72148 ? 50  LEU A CD2 1 
ATOM   377  N N   . ILE A 1 52  ? 62.84947 18.35822 91.49764  1.000 33.11028 ? 51  ILE A N   1 
ATOM   378  C CA  . ILE A 1 52  ? 62.14987 17.10058 91.23632  1.000 27.45779 ? 51  ILE A CA  1 
ATOM   379  C C   . ILE A 1 52  ? 62.72518 16.48700 89.96741  1.000 31.38403 ? 51  ILE A C   1 
ATOM   380  O O   . ILE A 1 52  ? 62.85865 17.16466 88.93806  1.000 27.79770 ? 51  ILE A O   1 
ATOM   381  C CB  . ILE A 1 52  ? 60.62289 17.28184 91.13420  1.000 30.20738 ? 51  ILE A CB  1 
ATOM   382  C CG1 . ILE A 1 52  ? 59.92518 15.92438 91.05572  1.000 27.97923 ? 51  ILE A CG1 1 
ATOM   383  C CG2 . ILE A 1 52  ? 60.23147 18.17050 89.97209  1.000 27.75820 ? 51  ILE A CG2 1 
ATOM   384  C CD1 . ILE A 1 52  ? 58.50511 15.95171 91.55695  1.000 26.91202 ? 51  ILE A CD1 1 
ATOM   385  N N   . LYS A 1 53  ? 63.06534 15.20695 90.03870  1.000 28.98863 ? 52  LYS A N   1 
ATOM   386  C CA  . LYS A 1 53  ? 63.72052 14.56851 88.91640  1.000 25.68745 ? 52  LYS A CA  1 
ATOM   387  C C   . LYS A 1 53  ? 62.67456 13.98978 87.95768  1.000 29.52070 ? 52  LYS A C   1 
ATOM   388  O O   . LYS A 1 53  ? 61.46386 14.09657 88.17602  1.000 33.12664 ? 52  LYS A O   1 
ATOM   389  C CB  . LYS A 1 53  ? 64.70567 13.52764 89.42947  1.000 23.46445 ? 52  LYS A CB  1 
ATOM   390  C CG  . LYS A 1 53  ? 65.91137 14.13761 90.11022  1.000 26.45686 ? 52  LYS A CG  1 
ATOM   391  C CD  . LYS A 1 53  ? 67.09233 13.15553 90.17306  1.000 34.22778 ? 52  LYS A CD  1 
ATOM   392  C CE  . LYS A 1 53  ? 67.61762 12.95948 91.61244  1.000 40.53333 ? 52  LYS A CE  1 
ATOM   393  N NZ  . LYS A 1 53  ? 68.33618 11.65965 91.87585  1.000 39.70946 ? 52  LYS A NZ  1 
ATOM   394  N N   . SER A 1 54  ? 63.13967 13.43693 86.83997  1.000 25.72565 ? 53  SER A N   1 
ATOM   395  C CA  . SER A 1 54  ? 62.24781 12.70495 85.95618  1.000 26.11521 ? 53  SER A CA  1 
ATOM   396  C C   . SER A 1 54  ? 61.72215 11.44834 86.64049  1.000 30.20778 ? 53  SER A C   1 
ATOM   397  O O   . SER A 1 54  ? 62.42027 10.79922 87.42423  1.000 32.50548 ? 53  SER A O   1 
ATOM   398  C CB  . SER A 1 54  ? 62.97268 12.32167 84.67462  1.000 29.27913 ? 53  SER A CB  1 
ATOM   399  O OG  . SER A 1 54  ? 62.15020 11.47727 83.89203  1.000 29.14660 ? 53  SER A OG  1 
ATOM   400  N N   . ARG A 1 55  ? 60.47637 11.09036 86.33000  1.000 33.14149 ? 54  ARG A N   1 
ATOM   401  C CA  . ARG A 1 55  ? 59.91761 9.87889  86.92453  1.000 32.44780 ? 54  ARG A CA  1 
ATOM   402  C C   . ARG A 1 55  ? 60.68957 8.63991  86.51650  1.000 31.37020 ? 54  ARG A C   1 
ATOM   403  O O   . ARG A 1 55  ? 60.56729 7.60923  87.17301  1.000 42.50986 ? 54  ARG A O   1 
ATOM   404  C CB  . ARG A 1 55  ? 58.43860 9.75226  86.59223  1.000 30.21145 ? 54  ARG A CB  1 
ATOM   405  C CG  . ARG A 1 55  ? 57.63946 10.49283 87.65136  1.000 40.04947 ? 54  ARG A CG  1 
ATOM   406  C CD  . ARG A 1 55  ? 56.44234 11.27098 87.14157  1.000 36.88181 ? 54  ARG A CD  1 
ATOM   407  N NE  . ARG A 1 55  ? 55.64259 11.69736 88.28335  1.000 42.69901 ? 54  ARG A NE  1 
ATOM   408  C CZ  . ARG A 1 55  ? 54.49115 12.35172 88.19616  1.000 49.17652 ? 54  ARG A CZ  1 
ATOM   409  N NH1 . ARG A 1 55  ? 53.99673 12.65574 87.00174  1.000 43.73193 ? 54  ARG A NH1 1 
ATOM   410  N NH2 . ARG A 1 55  ? 53.82989 12.69273 89.30316  1.000 41.31792 ? 54  ARG A NH2 1 
ATOM   411  N N   . ALA A 1 56  ? 61.46865 8.72377  85.44590  1.000 29.51222 ? 55  ALA A N   1 
ATOM   412  C CA  . ALA A 1 56  ? 62.38809 7.69217  84.99218  1.000 29.00880 ? 55  ALA A CA  1 
ATOM   413  C C   . ALA A 1 56  ? 63.64301 7.58249  85.86748  1.000 32.36615 ? 55  ALA A C   1 
ATOM   414  O O   . ALA A 1 56  ? 64.66751 7.05884  85.42544  1.000 36.02337 ? 55  ALA A O   1 
ATOM   415  C CB  . ALA A 1 56  ? 62.77402 7.97837  83.53945  1.000 29.55774 ? 55  ALA A CB  1 
ATOM   416  N N   . ILE A 1 57  ? 63.59551 8.07705  87.09953  1.000 39.90890 ? 56  ILE A N   1 
ATOM   417  C CA  . ILE A 1 57  ? 64.78478 8.13108  87.94987  1.000 41.77757 ? 56  ILE A CA  1 
ATOM   418  C C   . ILE A 1 57  ? 64.41317 7.77443  89.38272  1.000 39.81886 ? 56  ILE A C   1 
ATOM   419  O O   . ILE A 1 57  ? 65.08221 6.96670  90.03295  1.000 41.29284 ? 56  ILE A O   1 
ATOM   420  C CB  . ILE A 1 57  ? 65.42281 9.53764  87.87834  1.000 35.66109 ? 56  ILE A CB  1 
ATOM   421  C CG1 . ILE A 1 57  ? 66.24708 9.72775  86.60369  1.000 33.50217 ? 56  ILE A CG1 1 
ATOM   422  C CG2 . ILE A 1 57  ? 66.30328 9.81937  89.09260  1.000 36.94786 ? 56  ILE A CG2 1 
ATOM   423  C CD1 . ILE A 1 57  ? 67.58124 9.04764  86.61091  1.000 34.92092 ? 56  ILE A CD1 1 
ATOM   424  N N   . ASP A 1 58  ? 63.36304 8.41719  89.88338  1.000 47.81558 ? 57  ASP A N   1 
ATOM   425  C CA  . ASP A 1 58  ? 62.78299 8.20271  91.20178  1.000 54.70311 ? 57  ASP A CA  1 
ATOM   426  C C   . ASP A 1 58  ? 61.58890 9.13910  91.26058  1.000 54.82483 ? 57  ASP A C   1 
ATOM   427  O O   . ASP A 1 58  ? 60.44393 8.71141  91.46484  1.000 52.57177 ? 57  ASP A O   1 
ATOM   428  C CB  . ASP A 1 58  ? 63.78323 8.49839  92.32830  1.000 48.66801 ? 57  ASP A CB  1 
ATOM   429  N N   . GLY A 1 59  ? 61.86300 10.43244 91.08075  1.000 48.57493 ? 58  GLY A N   1 
ATOM   430  C CA  . GLY A 1 59  ? 60.84831 11.44547 91.16400  1.000 51.89659 ? 58  GLY A CA  1 
ATOM   431  C C   . GLY A 1 59  ? 60.69996 12.06228 92.53894  1.000 53.99423 ? 58  GLY A C   1 
ATOM   432  O O   . GLY A 1 59  ? 60.23095 13.19767 92.64478  1.000 52.48380 ? 58  GLY A O   1 
ATOM   433  N N   . THR A 1 60  ? 61.04057 11.31537 93.59495  1.000 49.21401 ? 59  THR A N   1 
ATOM   434  C CA  . THR A 1 60  ? 60.96675 11.79975 94.96360  1.000 50.79910 ? 59  THR A CA  1 
ATOM   435  C C   . THR A 1 60  ? 61.68113 13.15323 95.10946  1.000 50.92486 ? 59  THR A C   1 
ATOM   436  O O   . THR A 1 60  ? 62.90499 13.22709 94.92108  1.000 50.96232 ? 59  THR A O   1 
ATOM   437  C CB  . THR A 1 60  ? 61.59138 10.74961 95.87098  1.000 49.31661 ? 59  THR A CB  1 
ATOM   438  O OG1 . THR A 1 60  ? 61.75301 11.28613 97.18932  1.000 52.84000 ? 59  THR A OG1 1 
ATOM   439  C CG2 . THR A 1 60  ? 62.93641 10.25554 95.29746  1.000 55.39840 ? 59  THR A CG2 1 
ATOM   440  N N   . PRO A 1 61  ? 60.97118 14.21542 95.49518  1.000 40.40102 ? 60  PRO A N   1 
ATOM   441  C CA  . PRO A 1 61  ? 61.56411 15.55864 95.47731  1.000 40.14728 ? 60  PRO A CA  1 
ATOM   442  C C   . PRO A 1 61  ? 62.59292 15.82473 96.56880  1.000 42.44998 ? 60  PRO A C   1 
ATOM   443  O O   . PRO A 1 61  ? 62.51051 15.32371 97.69282  1.000 46.74973 ? 60  PRO A O   1 
ATOM   444  C CB  . PRO A 1 61  ? 60.34758 16.47332 95.65051  1.000 35.93237 ? 60  PRO A CB  1 
ATOM   445  C CG  . PRO A 1 61  ? 59.17634 15.63581 95.29145  1.000 38.64475 ? 60  PRO A CG  1 
ATOM   446  C CD  . PRO A 1 61  ? 59.52638 14.27295 95.76131  1.000 42.46161 ? 60  PRO A CD  1 
ATOM   447  N N   . GLN A 1 62  ? 63.56713 16.64875 96.21687  1.000 36.98258 ? 61  GLN A N   1 
ATOM   448  C CA  . GLN A 1 62  ? 64.57028 17.12989 97.14690  1.000 38.32572 ? 61  GLN A CA  1 
ATOM   449  C C   . GLN A 1 62  ? 64.36233 18.61876 97.36633  1.000 41.95443 ? 61  GLN A C   1 
ATOM   450  O O   . GLN A 1 62  ? 64.24087 19.38358 96.40418  1.000 43.09043 ? 61  GLN A O   1 
ATOM   451  C CB  . GLN A 1 62  ? 65.96827 16.88650 96.60820  1.000 42.94152 ? 61  GLN A CB  1 
ATOM   452  C CG  . GLN A 1 62  ? 66.33183 15.44346 96.51296  1.000 50.77841 ? 61  GLN A CG  1 
ATOM   453  C CD  . GLN A 1 62  ? 67.65577 15.29020 95.83407  1.000 60.05380 ? 61  GLN A CD  1 
ATOM   454  O OE1 . GLN A 1 62  ? 68.65326 15.86190 96.28984  1.000 54.62683 ? 61  GLN A OE1 1 
ATOM   455  N NE2 . GLN A 1 62  ? 67.68612 14.53309 94.72811  1.000 51.94122 ? 61  GLN A NE2 1 
ATOM   456  N N   . TYR A 1 63  ? 64.40256 19.03768 98.61331  1.000 45.77864 ? 62  TYR A N   1 
ATOM   457  C CA  . TYR A 1 63  ? 64.24998 20.43957 98.95231  1.000 40.34800 ? 62  TYR A CA  1 
ATOM   458  C C   . TYR A 1 63  ? 65.51183 20.90543 99.66506  1.000 35.17127 ? 62  TYR A C   1 
ATOM   459  O O   . TYR A 1 63  ? 66.46197 20.14241 99.84642  1.000 38.44880 ? 62  TYR A O   1 
ATOM   460  C CB  . TYR A 1 63  ? 63.00359 20.64848 99.80896  1.000 44.62637 ? 62  TYR A CB  1 
ATOM   461  C CG  . TYR A 1 63  ? 61.75612 19.89287 99.36092  1.000 47.24301 ? 62  TYR A CG  1 
ATOM   462  C CD1 . TYR A 1 63  ? 61.05190 20.27061 98.22067  1.000 42.55455 ? 62  TYR A CD1 1 
ATOM   463  C CD2 . TYR A 1 63  ? 61.26233 18.82354 100.10583 1.000 44.94344 ? 62  TYR A CD2 1 
ATOM   464  C CE1 . TYR A 1 63  ? 59.89458 19.59224 97.83285  1.000 36.09252 ? 62  TYR A CE1 1 
ATOM   465  C CE2 . TYR A 1 63  ? 60.11118 18.14858 99.72939  1.000 37.04574 ? 62  TYR A CE2 1 
ATOM   466  C CZ  . TYR A 1 63  ? 59.43530 18.53449 98.59404  1.000 34.83097 ? 62  TYR A CZ  1 
ATOM   467  O OH  . TYR A 1 63  ? 58.29432 17.86311 98.22819  1.000 34.68093 ? 62  TYR A OH  1 
ATOM   468  N N   . ALA A 1 64  ? 65.50548 22.15761 100.10238 1.000 34.42108 ? 63  ALA A N   1 
ATOM   469  C CA  . ALA A 1 64  ? 66.64761 22.73977 100.78446 1.000 30.17947 ? 63  ALA A CA  1 
ATOM   470  C C   . ALA A 1 64  ? 66.31229 22.94661 102.25432 1.000 37.46053 ? 63  ALA A C   1 
ATOM   471  O O   . ALA A 1 64  ? 65.15548 23.18718 102.60528 1.000 41.24028 ? 63  ALA A O   1 
ATOM   472  C CB  . ALA A 1 64  ? 67.04800 24.06001 100.14716 1.000 30.23287 ? 63  ALA A CB  1 
ATOM   473  N N   . ALA A 1 65  ? 67.32374 22.79439 103.10786 1.000 42.45547 ? 64  ALA A N   1 
ATOM   474  C CA  . ALA A 1 65  ? 67.20931 22.93429 104.55583 1.000 41.10510 ? 64  ALA A CA  1 
ATOM   475  C C   . ALA A 1 65  ? 66.13767 23.93725 104.95472 1.000 42.26021 ? 64  ALA A C   1 
ATOM   476  O O   . ALA A 1 65  ? 65.25071 23.63129 105.75738 1.000 44.79643 ? 64  ALA A O   1 
ATOM   477  C CB  . ALA A 1 65  ? 68.55274 23.35317 105.14942 1.000 46.21945 ? 64  ALA A CB  1 
ATOM   478  N N   . SER A 1 66  ? 66.22586 25.13996 104.38614 1.000 41.57236 ? 65  SER A N   1 
ATOM   479  C CA  . SER A 1 66  ? 65.28298 26.21112 104.68850 1.000 41.39034 ? 65  SER A CA  1 
ATOM   480  C C   . SER A 1 66  ? 63.84157 25.74660 104.55407 1.000 45.71603 ? 65  SER A C   1 
ATOM   481  O O   . SER A 1 66  ? 63.07904 25.74893 105.52808 1.000 49.97024 ? 65  SER A O   1 
ATOM   482  C CB  . SER A 1 66  ? 65.51319 27.37114 103.72543 1.000 41.83462 ? 65  SER A CB  1 
ATOM   483  O OG  . SER A 1 66  ? 66.89561 27.58619 103.53974 1.000 54.91538 ? 65  SER A OG  1 
ATOM   484  N N   . VAL A 1 67  ? 63.47118 25.26788 103.36761 1.000 36.07205 ? 66  VAL A N   1 
ATOM   485  C CA  . VAL A 1 67  ? 62.07037 24.97330 103.11129 1.000 36.90235 ? 66  VAL A CA  1 
ATOM   486  C C   . VAL A 1 67  ? 61.83895 23.51654 103.44885 1.000 33.31237 ? 66  VAL A C   1 
ATOM   487  O O   . VAL A 1 67  ? 60.76079 22.97524 103.18943 1.000 35.61871 ? 66  VAL A O   1 
ATOM   488  C CB  . VAL A 1 67  ? 61.69181 25.23706 101.63809 1.000 37.98340 ? 66  VAL A CB  1 
ATOM   489  C CG1 . VAL A 1 67  ? 61.97819 26.65747 101.25466 1.000 33.04951 ? 66  VAL A CG1 1 
ATOM   490  C CG2 . VAL A 1 67  ? 62.43654 24.27357 100.71461 1.000 37.43979 ? 66  VAL A CG2 1 
ATOM   491  N N   . LYS A 1 68  ? 62.80872 22.89819 104.10846 1.000 36.93740 ? 67  LYS A N   1 
ATOM   492  C CA  . LYS A 1 68  ? 62.74113 21.45489 104.31536 1.000 43.80459 ? 67  LYS A CA  1 
ATOM   493  C C   . LYS A 1 68  ? 61.61683 21.17997 105.29922 1.000 36.47488 ? 67  LYS A C   1 
ATOM   494  O O   . LYS A 1 68  ? 61.75143 21.41389 106.49985 1.000 38.92509 ? 67  LYS A O   1 
ATOM   495  C CB  . LYS A 1 68  ? 64.07538 20.89902 104.80199 1.000 40.69324 ? 67  LYS A CB  1 
ATOM   496  N N   . GLY A 1 69  ? 60.48730 20.72252 104.76950 1.000 33.04471 ? 68  GLY A N   1 
ATOM   497  C CA  . GLY A 1 69  ? 59.34464 20.29021 105.54791 1.000 31.88652 ? 68  GLY A CA  1 
ATOM   498  C C   . GLY A 1 69  ? 58.09866 21.12603 105.35294 1.000 40.68867 ? 68  GLY A C   1 
ATOM   499  O O   . GLY A 1 69  ? 57.00592 20.67063 105.70959 1.000 43.20550 ? 68  GLY A O   1 
ATOM   500  N N   . ARG A 1 70  ? 58.20705 22.33462 104.80046 1.000 33.91008 ? 69  ARG A N   1 
ATOM   501  C CA  . ARG A 1 70  ? 57.02094 23.13834 104.54877 1.000 35.69544 ? 69  ARG A CA  1 
ATOM   502  C C   . ARG A 1 70  ? 56.79609 23.46569 103.07834 1.000 38.59562 ? 69  ARG A C   1 
ATOM   503  O O   . ARG A 1 70  ? 55.71378 23.96603 102.74447 1.000 36.77133 ? 69  ARG A O   1 
ATOM   504  C CB  . ARG A 1 70  ? 56.99725 24.41996 105.39430 1.000 33.17396 ? 69  ARG A CB  1 
ATOM   505  C CG  . ARG A 1 70  ? 58.06866 25.39630 105.12500 1.000 36.44940 ? 69  ARG A CG  1 
ATOM   506  C CD  . ARG A 1 70  ? 58.07992 26.39593 106.22406 1.000 22.24472 ? 69  ARG A CD  1 
ATOM   507  N NE  . ARG A 1 70  ? 59.09521 27.37208 105.93692 1.000 26.40201 ? 69  ARG A NE  1 
ATOM   508  C CZ  . ARG A 1 70  ? 58.90635 28.40219 105.12925 1.000 26.64270 ? 69  ARG A CZ  1 
ATOM   509  N NH1 . ARG A 1 70  ? 57.73681 28.56899 104.53491 1.000 30.78578 ? 69  ARG A NH1 1 
ATOM   510  N NH2 . ARG A 1 70  ? 59.88755 29.25523 104.90749 1.000 29.56111 ? 69  ARG A NH2 1 
ATOM   511  N N   . PHE A 1 71  ? 57.78843 23.29313 102.20537 1.000 35.08649 ? 70  PHE A N   1 
ATOM   512  C CA  . PHE A 1 71  ? 57.47126 23.35878 100.78553 1.000 38.23652 ? 70  PHE A CA  1 
ATOM   513  C C   . PHE A 1 71  ? 57.37020 21.94615 100.23306 1.000 36.40168 ? 70  PHE A C   1 
ATOM   514  O O   . PHE A 1 71  ? 57.90725 21.00155 100.80798 1.000 41.77686 ? 70  PHE A O   1 
ATOM   515  C CB  . PHE A 1 71  ? 58.48742 24.11353 99.92300  1.000 37.30604 ? 70  PHE A CB  1 
ATOM   516  C CG  . PHE A 1 71  ? 58.66944 25.55214 100.27634 1.000 36.46922 ? 70  PHE A CG  1 
ATOM   517  C CD1 . PHE A 1 71  ? 58.06132 26.11989 101.37462 1.000 39.98496 ? 70  PHE A CD1 1 
ATOM   518  C CD2 . PHE A 1 71  ? 59.25931 26.38291 99.36238  1.000 36.31913 ? 70  PHE A CD2 1 
ATOM   519  C CE1 . PHE A 1 71  ? 58.23594 27.44191 101.65649 1.000 38.44371 ? 70  PHE A CE1 1 
ATOM   520  C CE2 . PHE A 1 71  ? 59.38746 27.72270 99.61018  1.000 43.33157 ? 70  PHE A CE2 1 
ATOM   521  C CZ  . PHE A 1 71  ? 58.88533 28.25528 100.76196 1.000 41.29968 ? 70  PHE A CZ  1 
ATOM   522  N N   . THR A 1 72  ? 56.63142 21.81068 99.13179  1.000 36.27224 ? 71  THR A N   1 
ATOM   523  C CA  . THR A 1 72  ? 56.44386 20.52887 98.45447  1.000 36.11532 ? 71  THR A CA  1 
ATOM   524  C C   . THR A 1 72  ? 56.35412 20.77652 96.95830  1.000 33.20037 ? 71  THR A C   1 
ATOM   525  O O   . THR A 1 72  ? 55.49070 21.52380 96.50122  1.000 29.95983 ? 71  THR A O   1 
ATOM   526  C CB  . THR A 1 72  ? 55.21170 19.74579 98.94982  1.000 35.77473 ? 71  THR A CB  1 
ATOM   527  O OG1 . THR A 1 72  ? 54.03540 20.56659 98.88659  1.000 32.90581 ? 71  THR A OG1 1 
ATOM   528  C CG2 . THR A 1 72  ? 55.40616 19.15565 100.33914 1.000 33.39461 ? 71  THR A CG2 1 
ATOM   529  N N   . ILE A 1 73  ? 57.22855 20.10343 96.21425  1.000 35.14912 ? 72  ILE A N   1 
ATOM   530  C CA  . ILE A 1 73  ? 57.38705 20.24099 94.77266  1.000 27.32809 ? 72  ILE A CA  1 
ATOM   531  C C   . ILE A 1 73  ? 56.72263 19.04060 94.10345  1.000 30.51700 ? 72  ILE A C   1 
ATOM   532  O O   . ILE A 1 73  ? 56.80406 17.91028 94.60051  1.000 33.58090 ? 72  ILE A O   1 
ATOM   533  C CB  . ILE A 1 73  ? 58.88834 20.33552 94.42932  1.000 31.90428 ? 72  ILE A CB  1 
ATOM   534  C CG1 . ILE A 1 73  ? 59.39481 21.75751 94.63887  1.000 36.29380 ? 72  ILE A CG1 1 
ATOM   535  C CG2 . ILE A 1 73  ? 59.17721 19.94025 93.00362  1.000 28.76213 ? 72  ILE A CG2 1 
ATOM   536  C CD1 . ILE A 1 73  ? 60.88401 21.83965 94.64684  1.000 31.78435 ? 72  ILE A CD1 1 
ATOM   537  N N   . SER A 1 74  ? 56.11406 19.26946 92.94431  1.000 30.76703 ? 73  SER A N   1 
ATOM   538  C CA  . SER A 1 74  ? 55.26513 18.27741 92.31106  1.000 26.44884 ? 73  SER A CA  1 
ATOM   539  C C   . SER A 1 74  ? 55.28680 18.45528 90.79453  1.000 42.09255 ? 73  SER A C   1 
ATOM   540  O O   . SER A 1 74  ? 55.56062 19.54240 90.27313  1.000 42.20383 ? 73  SER A O   1 
ATOM   541  C CB  . SER A 1 74  ? 53.83729 18.43342 92.84768  1.000 26.35702 ? 73  SER A CB  1 
ATOM   542  O OG  . SER A 1 74  ? 52.88775 17.67848 92.12371  1.000 34.45500 ? 73  SER A OG  1 
ATOM   543  N N   . ARG A 1 75  ? 54.91642 17.38886 90.08751  1.000 39.41809 ? 74  ARG A N   1 
ATOM   544  C CA  . ARG A 1 75  ? 54.93954 17.37319 88.63470  1.000 36.66577 ? 74  ARG A CA  1 
ATOM   545  C C   . ARG A 1 75  ? 53.61577 16.84809 88.13135  1.000 35.44431 ? 74  ARG A C   1 
ATOM   546  O O   . ARG A 1 75  ? 53.00062 15.97463 88.74599  1.000 33.64697 ? 74  ARG A O   1 
ATOM   547  C CB  . ARG A 1 75  ? 55.95788 16.41609 88.03484  1.000 37.59771 ? 74  ARG A CB  1 
ATOM   548  C CG  . ARG A 1 75  ? 57.38156 16.59733 88.36171  1.000 43.93277 ? 74  ARG A CG  1 
ATOM   549  C CD  . ARG A 1 75  ? 58.08192 15.35666 87.83439  1.000 42.19582 ? 74  ARG A CD  1 
ATOM   550  N NE  . ARG A 1 75  ? 58.15833 15.43621 86.38361  1.000 34.76999 ? 74  ARG A NE  1 
ATOM   551  C CZ  . ARG A 1 75  ? 59.25628 15.74163 85.70383  1.000 32.20060 ? 74  ARG A CZ  1 
ATOM   552  N NH1 . ARG A 1 75  ? 60.40852 15.97115 86.32426  1.000 22.94936 ? 74  ARG A NH1 1 
ATOM   553  N NH2 . ARG A 1 75  ? 59.19553 15.80310 84.38924  1.000 35.50928 ? 74  ARG A NH2 1 
ATOM   554  N N   . ASP A 1 76  ? 53.25356 17.28779 86.93849  1.000 32.38158 ? 75  ASP A N   1 
ATOM   555  C CA  . ASP A 1 76  ? 52.13102 16.69830 86.22874  1.000 37.11365 ? 75  ASP A CA  1 
ATOM   556  C C   . ASP A 1 76  ? 52.66131 16.48188 84.82313  1.000 39.15626 ? 75  ASP A C   1 
ATOM   557  O O   . ASP A 1 76  ? 52.56500 17.36839 83.96820  1.000 34.58329 ? 75  ASP A O   1 
ATOM   558  C CB  . ASP A 1 76  ? 50.89718 17.56992 86.24904  1.000 32.05547 ? 75  ASP A CB  1 
ATOM   559  C CG  . ASP A 1 76  ? 49.72506 16.90751 85.57152  1.000 36.15868 ? 75  ASP A CG  1 
ATOM   560  O OD1 . ASP A 1 76  ? 49.87105 15.74077 85.16040  1.000 44.09209 ? 75  ASP A OD1 1 
ATOM   561  O OD2 . ASP A 1 76  ? 48.66569 17.53860 85.42859  1.000 33.76762 ? 75  ASP A OD2 1 
ATOM   562  N N   . ASP A 1 77  ? 53.21719 15.28920 84.59874  1.000 36.09357 ? 76  ASP A N   1 
ATOM   563  C CA  . ASP A 1 77  ? 53.78114 14.98977 83.29742  1.000 34.05230 ? 76  ASP A CA  1 
ATOM   564  C C   . ASP A 1 77  ? 52.68756 14.95403 82.24214  1.000 39.13217 ? 76  ASP A C   1 
ATOM   565  O O   . ASP A 1 77  ? 52.95061 15.21493 81.06027  1.000 38.06846 ? 76  ASP A O   1 
ATOM   566  C CB  . ASP A 1 77  ? 54.56609 13.68286 83.35408  1.000 40.47864 ? 76  ASP A CB  1 
ATOM   567  C CG  . ASP A 1 77  ? 55.95814 13.86657 83.93092  1.000 41.14480 ? 76  ASP A CG  1 
ATOM   568  O OD1 . ASP A 1 77  ? 56.34745 15.02955 84.16954  1.000 42.43533 ? 76  ASP A OD1 1 
ATOM   569  O OD2 . ASP A 1 77  ? 56.66607 12.85819 84.14649  1.000 41.35162 ? 76  ASP A OD2 1 
ATOM   570  N N   . SER A 1 78  ? 51.44507 14.69562 82.65526  1.000 35.89391 ? 77  SER A N   1 
ATOM   571  C CA  . SER A 1 78  ? 50.36472 14.64341 81.68248  1.000 33.38377 ? 77  SER A CA  1 
ATOM   572  C C   . SER A 1 78  ? 50.08847 16.01030 81.07965  1.000 37.33572 ? 77  SER A C   1 
ATOM   573  O O   . SER A 1 78  ? 49.56314 16.09847 79.96387  1.000 42.30206 ? 77  SER A O   1 
ATOM   574  C CB  . SER A 1 78  ? 49.09458 14.11009 82.32536  1.000 33.75224 ? 77  SER A CB  1 
ATOM   575  O OG  . SER A 1 78  ? 47.99163 14.32851 81.47500  1.000 41.95746 ? 77  SER A OG  1 
ATOM   576  N N   . ASN A 1 79  ? 50.40888 17.08497 81.79876  1.000 36.79616 ? 78  ASN A N   1 
ATOM   577  C CA  . ASN A 1 79  ? 50.20697 18.42898 81.28061  1.000 30.02533 ? 78  ASN A CA  1 
ATOM   578  C C   . ASN A 1 79  ? 51.46893 19.27395 81.33545  1.000 31.87766 ? 78  ASN A C   1 
ATOM   579  O O   . ASN A 1 79  ? 51.38771 20.49868 81.21989  1.000 36.64875 ? 78  ASN A O   1 
ATOM   580  C CB  . ASN A 1 79  ? 49.05203 19.10342 82.01220  1.000 30.84922 ? 78  ASN A CB  1 
ATOM   581  C CG  . ASN A 1 79  ? 47.71929 18.47223 81.65841  1.000 36.11630 ? 78  ASN A CG  1 
ATOM   582  O OD1 . ASN A 1 79  ? 47.36039 18.36363 80.47773  1.000 38.65676 ? 78  ASN A OD1 1 
ATOM   583  N ND2 . ASN A 1 79  ? 46.99046 18.02442 82.67156  1.000 31.18753 ? 78  ASN A ND2 1 
ATOM   584  N N   . SER A 1 80  ? 52.63056 18.65041 81.50691  1.000 30.71913 ? 79  SER A N   1 
ATOM   585  C CA  . SER A 1 80  ? 53.91566 19.33827 81.38387  1.000 33.22758 ? 79  SER A CA  1 
ATOM   586  C C   . SER A 1 80  ? 53.97893 20.56834 82.29605  1.000 39.74577 ? 79  SER A C   1 
ATOM   587  O O   . SER A 1 80  ? 54.24588 21.69873 81.86157  1.000 34.96701 ? 79  SER A O   1 
ATOM   588  C CB  . SER A 1 80  ? 54.18140 19.72162 79.92838  1.000 27.85702 ? 79  SER A CB  1 
ATOM   589  O OG  . SER A 1 80  ? 53.94996 18.62246 79.06949  1.000 38.55421 ? 79  SER A OG  1 
ATOM   590  N N   . ILE A 1 81  ? 53.72959 20.34241 83.58260  1.000 31.94138 ? 80  ILE A N   1 
ATOM   591  C CA  . ILE A 1 81  ? 53.57470 21.45486 84.50678  1.000 31.76884 ? 80  ILE A CA  1 
ATOM   592  C C   . ILE A 1 81  ? 54.10806 21.05468 85.87410  1.000 27.94929 ? 80  ILE A C   1 
ATOM   593  O O   . ILE A 1 81  ? 53.68905 20.05344 86.46167  1.000 30.48984 ? 80  ILE A O   1 
ATOM   594  C CB  . ILE A 1 81  ? 52.10628 21.92272 84.53961  1.000 31.97199 ? 80  ILE A CB  1 
ATOM   595  C CG1 . ILE A 1 81  ? 51.97938 23.30501 85.17300  1.000 32.34891 ? 80  ILE A CG1 1 
ATOM   596  C CG2 . ILE A 1 81  ? 51.19600 20.90405 85.18580  1.000 31.54956 ? 80  ILE A CG2 1 
ATOM   597  C CD1 . ILE A 1 81  ? 50.56183 23.81665 85.15025  1.000 32.48894 ? 80  ILE A CD1 1 
ATOM   598  N N   . ALA A 1 82  ? 55.06995 21.81551 86.36612  1.000 29.60479 ? 81  ALA A N   1 
ATOM   599  C CA  . ALA A 1 82  ? 55.63089 21.61265 87.68886  1.000 32.80521 ? 81  ALA A CA  1 
ATOM   600  C C   . ALA A 1 82  ? 55.02019 22.61264 88.65339  1.000 28.91260 ? 81  ALA A C   1 
ATOM   601  O O   . ALA A 1 82  ? 54.50128 23.65172 88.24758  1.000 28.76416 ? 81  ALA A O   1 
ATOM   602  C CB  . ALA A 1 82  ? 57.15669 21.75473 87.66224  1.000 26.22156 ? 81  ALA A CB  1 
ATOM   603  N N   . TYR A 1 83  ? 55.06118 22.26837 89.94132  1.000 34.05666 ? 82  TYR A N   1 
ATOM   604  C CA  . TYR A 1 83  ? 54.41508 23.05364 90.98647  1.000 33.90728 ? 82  TYR A CA  1 
ATOM   605  C C   . TYR A 1 83  ? 55.35051 23.25430 92.16707  1.000 31.05395 ? 82  TYR A C   1 
ATOM   606  O O   . TYR A 1 83  ? 56.14934 22.37831 92.49573  1.000 32.34067 ? 82  TYR A O   1 
ATOM   607  C CB  . TYR A 1 83  ? 53.14914 22.37686 91.50728  1.000 30.17524 ? 82  TYR A CB  1 
ATOM   608  C CG  . TYR A 1 83  ? 52.03145 22.21063 90.50283  1.000 31.18107 ? 82  TYR A CG  1 
ATOM   609  C CD1 . TYR A 1 83  ? 51.76784 20.97695 89.93079  1.000 24.36460 ? 82  TYR A CD1 1 
ATOM   610  C CD2 . TYR A 1 83  ? 51.22784 23.28785 90.13947  1.000 33.26762 ? 82  TYR A CD2 1 
ATOM   611  C CE1 . TYR A 1 83  ? 50.74173 20.81851 89.03359  1.000 22.84925 ? 82  TYR A CE1 1 
ATOM   612  C CE2 . TYR A 1 83  ? 50.20459 23.13504 89.22473  1.000 34.19677 ? 82  TYR A CE2 1 
ATOM   613  C CZ  . TYR A 1 83  ? 49.96303 21.89416 88.68144  1.000 26.63841 ? 82  TYR A CZ  1 
ATOM   614  O OH  . TYR A 1 83  ? 48.93455 21.73511 87.78821  1.000 25.01838 ? 82  TYR A OH  1 
ATOM   615  N N   . LEU A 1 84  ? 55.20360 24.39489 92.83792  1.000 33.06824 ? 83  LEU A N   1 
ATOM   616  C CA  . LEU A 1 84  ? 55.81300 24.63144 94.14415  1.000 31.35715 ? 83  LEU A CA  1 
ATOM   617  C C   . LEU A 1 84  ? 54.70388 25.01773 95.10585  1.000 31.84603 ? 83  LEU A C   1 
ATOM   618  O O   . LEU A 1 84  ? 53.99659 26.00535 94.88311  1.000 31.71531 ? 83  LEU A O   1 
ATOM   619  C CB  . LEU A 1 84  ? 56.88371 25.72600 94.10452  1.000 29.87087 ? 83  LEU A CB  1 
ATOM   620  C CG  . LEU A 1 84  ? 57.61778 26.01726 95.42373  1.000 26.70284 ? 83  LEU A CG  1 
ATOM   621  C CD1 . LEU A 1 84  ? 58.00582 24.74051 96.15833  1.000 30.49570 ? 83  LEU A CD1 1 
ATOM   622  C CD2 . LEU A 1 84  ? 58.86351 26.77987 95.13427  1.000 23.01578 ? 83  LEU A CD2 1 
ATOM   623  N N   . GLN A 1 85  ? 54.54161 24.22924 96.15379  1.000 33.04599 ? 84  GLN A N   1 
ATOM   624  C CA  . GLN A 1 85  ? 53.56673 24.49878 97.19475  1.000 29.56516 ? 84  GLN A CA  1 
ATOM   625  C C   . GLN A 1 85  ? 54.28975 25.11768 98.37983  1.000 30.87471 ? 84  GLN A C   1 
ATOM   626  O O   . GLN A 1 85  ? 55.27506 24.56302 98.87232  1.000 31.27991 ? 84  GLN A O   1 
ATOM   627  C CB  . GLN A 1 85  ? 52.85020 23.21955 97.60672  1.000 28.15938 ? 84  GLN A CB  1 
ATOM   628  C CG  . GLN A 1 85  ? 51.92374 23.39666 98.76040  1.000 31.92055 ? 84  GLN A CG  1 
ATOM   629  C CD  . GLN A 1 85  ? 50.60243 23.94948 98.33010  1.000 34.07427 ? 84  GLN A CD  1 
ATOM   630  O OE1 . GLN A 1 85  ? 50.00285 23.47997 97.35013  1.000 32.13276 ? 84  GLN A OE1 1 
ATOM   631  N NE2 . GLN A 1 85  ? 50.12174 24.95011 99.05896  1.000 30.47086 ? 84  GLN A NE2 1 
ATOM   632  N N   . MET A 1 86  ? 53.81132 26.27348 98.81967  1.000 39.35970 ? 85  MET A N   1 
ATOM   633  C CA  . MET A 1 86  ? 54.41827 27.00769 99.91707  1.000 36.55031 ? 85  MET A CA  1 
ATOM   634  C C   . MET A 1 86  ? 53.47261 27.04185 101.09907 1.000 31.40642 ? 85  MET A C   1 
ATOM   635  O O   . MET A 1 86  ? 52.32695 27.48356 100.96281 1.000 28.53976 ? 85  MET A O   1 
ATOM   636  C CB  . MET A 1 86  ? 54.71312 28.42929 99.49061  1.000 36.57760 ? 85  MET A CB  1 
ATOM   637  C CG  . MET A 1 86  ? 55.96101 28.52601 98.72122  1.000 37.85542 ? 85  MET A CG  1 
ATOM   638  S SD  . MET A 1 86  ? 55.90570 29.95351 97.64201  1.000 38.41150 ? 85  MET A SD  1 
ATOM   639  C CE  . MET A 1 86  ? 57.60805 29.81450 97.16239  1.000 42.99813 ? 85  MET A CE  1 
ATOM   640  N N   . ASN A 1 87  ? 53.97883 26.65366 102.26326 1.000 29.05940 ? 86  ASN A N   1 
ATOM   641  C CA  . ASN A 1 87  ? 53.18853 26.62113 103.48034 1.000 29.02439 ? 86  ASN A CA  1 
ATOM   642  C C   . ASN A 1 87  ? 53.83036 27.44565 104.58288 1.000 26.35848 ? 86  ASN A C   1 
ATOM   643  O O   . ASN A 1 87  ? 55.05492 27.57657 104.65625 1.000 27.72910 ? 86  ASN A O   1 
ATOM   644  C CB  . ASN A 1 87  ? 53.01028 25.19120 103.94624 1.000 32.02391 ? 86  ASN A CB  1 
ATOM   645  C CG  . ASN A 1 87  ? 52.20833 24.39588 102.97942 1.000 32.66694 ? 86  ASN A CG  1 
ATOM   646  O OD1 . ASN A 1 87  ? 51.08205 24.76860 102.66007 1.000 33.59880 ? 86  ASN A OD1 1 
ATOM   647  N ND2 . ASN A 1 87  ? 52.78898 23.31971 102.45976 1.000 32.67376 ? 86  ASN A ND2 1 
ATOM   648  N N   . SER A 1 88  ? 52.98319 27.98657 105.44904 1.000 27.68425 ? 87  SER A N   1 
ATOM   649  C CA  . SER A 1 88  ? 53.42970 28.81604 106.55639 1.000 27.50504 ? 87  SER A CA  1 
ATOM   650  C C   . SER A 1 88  ? 54.42022 29.86487 106.06201 1.000 32.91170 ? 87  SER A C   1 
ATOM   651  O O   . SER A 1 88  ? 55.59346 29.87907 106.43409 1.000 36.71112 ? 87  SER A O   1 
ATOM   652  C CB  . SER A 1 88  ? 54.01620 27.96408 107.67828 1.000 29.79898 ? 87  SER A CB  1 
ATOM   653  O OG  . SER A 1 88  ? 52.97236 27.47194 108.51284 1.000 33.17422 ? 87  SER A OG  1 
ATOM   654  N N   . LEU A 1 89  ? 53.93818 30.70068 105.14488 1.000 31.53705 ? 88  LEU A N   1 
ATOM   655  C CA  . LEU A 1 89  ? 54.77334 31.72829 104.52978 1.000 33.87929 ? 88  LEU A CA  1 
ATOM   656  C C   . LEU A 1 89  ? 55.17936 32.79195 105.54854 1.000 40.25140 ? 88  LEU A C   1 
ATOM   657  O O   . LEU A 1 89  ? 54.31400 33.46213 106.12473 1.000 40.55209 ? 88  LEU A O   1 
ATOM   658  C CB  . LEU A 1 89  ? 54.00443 32.39121 103.39164 1.000 30.18901 ? 88  LEU A CB  1 
ATOM   659  C CG  . LEU A 1 89  ? 53.74684 31.67397 102.07959 1.000 29.31690 ? 88  LEU A CG  1 
ATOM   660  C CD1 . LEU A 1 89  ? 52.63190 32.39072 101.37146 1.000 26.19670 ? 88  LEU A CD1 1 
ATOM   661  C CD2 . LEU A 1 89  ? 54.99968 31.66455 101.24298 1.000 26.43528 ? 88  LEU A CD2 1 
ATOM   662  N N   . THR A 1 90  ? 56.48436 33.00664 105.72074 1.000 39.81082 ? 89  THR A N   1 
ATOM   663  C CA  . THR A 1 90  ? 56.96399 34.12068 106.52817 1.000 35.20063 ? 89  THR A CA  1 
ATOM   664  C C   . THR A 1 90  ? 57.45139 35.20954 105.59006 1.000 36.40264 ? 89  THR A C   1 
ATOM   665  O O   . THR A 1 90  ? 57.66493 34.97560 104.39989 1.000 38.82086 ? 89  THR A O   1 
ATOM   666  C CB  . THR A 1 90  ? 58.10841 33.71856 107.47872 1.000 35.42845 ? 89  THR A CB  1 
ATOM   667  O OG1 . THR A 1 90  ? 59.34570 33.63495 106.75453 1.000 38.02663 ? 89  THR A OG1 1 
ATOM   668  C CG2 . THR A 1 90  ? 57.83318 32.39149 108.14180 1.000 29.71089 ? 89  THR A CG2 1 
ATOM   669  N N   . THR A 1 91  ? 57.65492 36.40521 106.14310 1.000 38.48040 ? 90  THR A N   1 
ATOM   670  C CA  . THR A 1 91  ? 58.16651 37.48751 105.31677 1.000 36.50506 ? 90  THR A CA  1 
ATOM   671  C C   . THR A 1 91  ? 59.58448 37.20932 104.83964 1.000 36.82572 ? 90  THR A C   1 
ATOM   672  O O   . THR A 1 91  ? 60.00575 37.77807 103.82580 1.000 40.46918 ? 90  THR A O   1 
ATOM   673  C CB  . THR A 1 91  ? 58.10048 38.82016 106.05962 1.000 36.30489 ? 90  THR A CB  1 
ATOM   674  O OG1 . THR A 1 91  ? 59.23463 38.94223 106.92060 1.000 41.26497 ? 90  THR A OG1 1 
ATOM   675  C CG2 . THR A 1 91  ? 56.83486 38.88854 106.88415 1.000 37.01592 ? 90  THR A CG2 1 
ATOM   676  N N   . GLU A 1 92  ? 60.33798 36.36369 105.54284 1.000 34.05532 ? 91  GLU A N   1 
ATOM   677  C CA  . GLU A 1 92  ? 61.65165 35.99354 105.02781 1.000 38.40021 ? 91  GLU A CA  1 
ATOM   678  C C   . GLU A 1 92  ? 61.56194 35.06743 103.82218 1.000 37.39399 ? 91  GLU A C   1 
ATOM   679  O O   . GLU A 1 92  ? 62.59971 34.62690 103.31231 1.000 37.18227 ? 91  GLU A O   1 
ATOM   680  C CB  . GLU A 1 92  ? 62.49633 35.33766 106.11863 1.000 42.62935 ? 91  GLU A CB  1 
ATOM   681  C CG  . GLU A 1 92  ? 62.83599 36.20858 107.35532 1.000 57.45736 ? 91  GLU A CG  1 
ATOM   682  C CD  . GLU A 1 92  ? 63.95276 37.26255 107.15914 1.000 74.04620 ? 91  GLU A CD  1 
ATOM   683  O OE1 . GLU A 1 92  ? 64.22795 37.67684 106.00481 1.000 77.12232 ? 91  GLU A OE1 1 
ATOM   684  O OE2 . GLU A 1 92  ? 64.59978 37.61077 108.19145 1.000 81.94395 ? 91  GLU A OE2 1 
ATOM   685  N N   . ASP A 1 93  ? 60.35290 34.78167 103.34502 1.000 36.26277 ? 92  ASP A N   1 
ATOM   686  C CA  . ASP A 1 93  ? 60.12530 34.01800 102.12781 1.000 34.65912 ? 92  ASP A CA  1 
ATOM   687  C C   . ASP A 1 93  ? 59.81357 34.89680 100.92108 1.000 36.87092 ? 92  ASP A C   1 
ATOM   688  O O   . ASP A 1 93  ? 59.62705 34.37041 99.82069  1.000 43.10127 ? 92  ASP A O   1 
ATOM   689  C CB  . ASP A 1 93  ? 58.95285 33.05982 102.33631 1.000 36.83551 ? 92  ASP A CB  1 
ATOM   690  C CG  . ASP A 1 93  ? 59.34752 31.80508 103.04067 1.000 35.02453 ? 92  ASP A CG  1 
ATOM   691  O OD1 . ASP A 1 93  ? 60.52355 31.41293 102.92432 1.000 34.78787 ? 92  ASP A OD1 1 
ATOM   692  O OD2 . ASP A 1 93  ? 58.46952 31.21631 103.71124 1.000 34.89201 ? 92  ASP A OD2 1 
ATOM   693  N N   . THR A 1 94  ? 59.73466 36.21236 101.09931 1.000 39.10878 ? 93  THR A N   1 
ATOM   694  C CA  . THR A 1 94  ? 59.42457 37.12131 100.00096 1.000 33.51356 ? 93  THR A CA  1 
ATOM   695  C C   . THR A 1 94  ? 60.52260 37.07926 98.96226  1.000 27.04280 ? 93  THR A C   1 
ATOM   696  O O   . THR A 1 94  ? 61.69592 37.29047 99.29211  1.000 30.12536 ? 93  THR A O   1 
ATOM   697  C CB  . THR A 1 94  ? 59.25346 38.54688 100.53055 1.000 33.01392 ? 93  THR A CB  1 
ATOM   698  O OG1 . THR A 1 94  ? 58.08366 38.61531 101.35971 1.000 33.03330 ? 93  THR A OG1 1 
ATOM   699  C CG2 . THR A 1 94  ? 59.11224 39.51766 99.37568  1.000 30.90856 ? 93  THR A CG2 1 
ATOM   700  N N   . ALA A 1 95  ? 60.15390 36.77874 97.71917  1.000 24.88845 ? 94  ALA A N   1 
ATOM   701  C CA  . ALA A 1 95  ? 61.16002 36.71961 96.66623  1.000 24.16018 ? 94  ALA A CA  1 
ATOM   702  C C   . ALA A 1 95  ? 60.49945 36.49210 95.32127  1.000 24.80387 ? 94  ALA A C   1 
ATOM   703  O O   . ALA A 1 95  ? 59.28997 36.25854 95.22936  1.000 23.51207 ? 94  ALA A O   1 
ATOM   704  C CB  . ALA A 1 95  ? 62.16765 35.62692 96.92930  1.000 26.70093 ? 94  ALA A CB  1 
ATOM   705  N N   . ILE A 1 96  ? 61.32621 36.58167 94.27302  1.000 26.63674 ? 95  ILE A N   1 
ATOM   706  C CA  . ILE A 1 96  ? 60.97881 36.10051 92.93877  1.000 29.51183 ? 95  ILE A CA  1 
ATOM   707  C C   . ILE A 1 96  ? 61.40611 34.64706 92.80351  1.000 25.85568 ? 95  ILE A C   1 
ATOM   708  O O   . ILE A 1 96  ? 62.57351 34.30527 93.02658  1.000 25.11223 ? 95  ILE A O   1 
ATOM   709  C CB  . ILE A 1 96  ? 61.64402 36.95658 91.84841  1.000 29.23225 ? 95  ILE A CB  1 
ATOM   710  C CG1 . ILE A 1 96  ? 61.28863 38.43633 92.02611  1.000 24.16970 ? 95  ILE A CG1 1 
ATOM   711  C CG2 . ILE A 1 96  ? 61.24179 36.45245 90.46314  1.000 22.42846 ? 95  ILE A CG2 1 
ATOM   712  C CD1 . ILE A 1 96  ? 62.21684 39.37712 91.25684  1.000 23.39314 ? 95  ILE A CD1 1 
ATOM   713  N N   . TYR A 1 97  ? 60.47138 33.80820 92.37299  1.000 32.94525 ? 96  TYR A N   1 
ATOM   714  C CA  . TYR A 1 97  ? 60.64508 32.36309 92.27595  1.000 29.32270 ? 96  TYR A CA  1 
ATOM   715  C C   . TYR A 1 97  ? 60.73097 31.94784 90.81052  1.000 27.52650 ? 96  TYR A C   1 
ATOM   716  O O   . TYR A 1 97  ? 59.87258 32.31592 90.00248  1.000 25.53227 ? 96  TYR A O   1 
ATOM   717  C CB  . TYR A 1 97  ? 59.50203 31.64939 92.99141  1.000 26.29160 ? 96  TYR A CB  1 
ATOM   718  C CG  . TYR A 1 97  ? 59.61198 31.78660 94.49391  1.000 31.65012 ? 96  TYR A CG  1 
ATOM   719  C CD1 . TYR A 1 97  ? 58.90678 32.76752 95.16814  1.000 27.97251 ? 96  TYR A CD1 1 
ATOM   720  C CD2 . TYR A 1 97  ? 60.44485 30.93817 95.23418  1.000 32.26398 ? 96  TYR A CD2 1 
ATOM   721  C CE1 . TYR A 1 97  ? 59.00922 32.90515 96.53425  1.000 32.06824 ? 96  TYR A CE1 1 
ATOM   722  C CE2 . TYR A 1 97  ? 60.56837 31.06774 96.59757  1.000 31.78541 ? 96  TYR A CE2 1 
ATOM   723  C CZ  . TYR A 1 97  ? 59.84567 32.06150 97.24546  1.000 38.92963 ? 96  TYR A CZ  1 
ATOM   724  O OH  . TYR A 1 97  ? 59.93342 32.19693 98.61083  1.000 41.97479 ? 96  TYR A OH  1 
ATOM   725  N N   . TYR A 1 98  ? 61.79126 31.22811 90.46601  1.000 29.95841 ? 97  TYR A N   1 
ATOM   726  C CA  . TYR A 1 98  ? 62.11085 30.86282 89.09349  1.000 27.90594 ? 97  TYR A CA  1 
ATOM   727  C C   . TYR A 1 98  ? 61.99120 29.36285 88.88319  1.000 29.93871 ? 97  TYR A C   1 
ATOM   728  O O   . TYR A 1 98  ? 62.25181 28.57157 89.79462  1.000 31.12950 ? 97  TYR A O   1 
ATOM   729  C CB  . TYR A 1 98  ? 63.52363 31.29780 88.72778  1.000 29.72084 ? 97  TYR A CB  1 
ATOM   730  C CG  . TYR A 1 98  ? 63.74782 32.78862 88.80303  1.000 31.96256 ? 97  TYR A CG  1 
ATOM   731  C CD1 . TYR A 1 98  ? 64.34315 33.36664 89.91834  1.000 25.10120 ? 97  TYR A CD1 1 
ATOM   732  C CD2 . TYR A 1 98  ? 63.37985 33.61238 87.74653  1.000 30.84182 ? 97  TYR A CD2 1 
ATOM   733  C CE1 . TYR A 1 98  ? 64.55765 34.71468 89.97709  1.000 33.39359 ? 97  TYR A CE1 1 
ATOM   734  C CE2 . TYR A 1 98  ? 63.59213 34.95687 87.79229  1.000 33.90179 ? 97  TYR A CE2 1 
ATOM   735  C CZ  . TYR A 1 98  ? 64.17893 35.51747 88.90732  1.000 37.43210 ? 97  TYR A CZ  1 
ATOM   736  O OH  . TYR A 1 98  ? 64.38018 36.88733 88.94621  1.000 34.12408 ? 97  TYR A OH  1 
ATOM   737  N N   . CYS A 1 99  ? 61.59626 28.98771 87.66655  1.000 30.83588 ? 98  CYS A N   1 
ATOM   738  C CA  . CYS A 1 99  ? 61.48647 27.59623 87.23822  1.000 35.32847 ? 98  CYS A CA  1 
ATOM   739  C C   . CYS A 1 99  ? 62.66105 27.23446 86.33659  1.000 34.56375 ? 98  CYS A C   1 
ATOM   740  O O   . CYS A 1 99  ? 63.15134 28.07422 85.57998  1.000 28.94104 ? 98  CYS A O   1 
ATOM   741  C CB  . CYS A 1 99  ? 60.17593 27.37429 86.49030  1.000 36.17622 ? 98  CYS A CB  1 
ATOM   742  S SG  . CYS A 1 99  ? 59.67368 25.66098 86.35472  1.000 56.01437 ? 98  CYS A SG  1 
ATOM   743  N N   . ALA A 1 100 ? 63.14568 26.00061 86.43540  1.000 31.43639 ? 99  ALA A N   1 
ATOM   744  C CA  . ALA A 1 100 ? 64.35442 25.68181 85.69525  1.000 27.06178 ? 99  ALA A CA  1 
ATOM   745  C C   . ALA A 1 100 ? 64.34757 24.24802 85.19066  1.000 28.30772 ? 99  ALA A C   1 
ATOM   746  O O   . ALA A 1 100 ? 63.78530 23.34798 85.81484  1.000 34.96785 ? 99  ALA A O   1 
ATOM   747  C CB  . ALA A 1 100 ? 65.59527 25.93755 86.54589  1.000 27.13419 ? 99  ALA A CB  1 
ATOM   748  N N   . ARG A 1 101 ? 64.95655 24.06628 84.02368  1.000 27.88552 ? 100 ARG A N   1 
ATOM   749  C CA  . ARG A 1 101 ? 65.13917 22.77806 83.37193  1.000 22.87086 ? 100 ARG A CA  1 
ATOM   750  C C   . ARG A 1 101 ? 66.58735 22.33953 83.57207  1.000 31.78149 ? 100 ARG A C   1 
ATOM   751  O O   . ARG A 1 101 ? 67.49965 23.16225 83.43629  1.000 27.74868 ? 100 ARG A O   1 
ATOM   752  C CB  . ARG A 1 101 ? 64.81730 22.93811 81.88964  1.000 24.71438 ? 100 ARG A CB  1 
ATOM   753  C CG  . ARG A 1 101 ? 64.53613 21.71979 81.10786  1.000 27.73414 ? 100 ARG A CG  1 
ATOM   754  C CD  . ARG A 1 101 ? 65.74870 21.21040 80.41839  1.000 31.29808 ? 100 ARG A CD  1 
ATOM   755  N NE  . ARG A 1 101 ? 66.26388 21.81363 79.18431  1.000 37.45870 ? 100 ARG A NE  1 
ATOM   756  C CZ  . ARG A 1 101 ? 65.84080 21.45063 77.97778  1.000 32.74022 ? 100 ARG A CZ  1 
ATOM   757  N NH1 . ARG A 1 101 ? 64.89971 20.53392 77.88647  1.000 32.80339 ? 100 ARG A NH1 1 
ATOM   758  N NH2 . ARG A 1 101 ? 66.34972 21.96240 76.87438  1.000 35.80599 ? 100 ARG A NH2 1 
ATOM   759  N N   . ASP A 1 102 ? 66.79672 21.06978 83.95517  1.000 33.82497 ? 101 ASP A N   1 
ATOM   760  C CA  . ASP A 1 102 ? 68.13071 20.45861 83.88696  1.000 31.97398 ? 101 ASP A CA  1 
ATOM   761  C C   . ASP A 1 102 ? 68.69098 20.61638 82.48403  1.000 29.83683 ? 101 ASP A C   1 
ATOM   762  O O   . ASP A 1 102 ? 68.01607 20.30074 81.51238  1.000 35.75548 ? 101 ASP A O   1 
ATOM   763  C CB  . ASP A 1 102 ? 68.09745 18.96647 84.24306  1.000 31.45121 ? 101 ASP A CB  1 
ATOM   764  C CG  . ASP A 1 102 ? 69.50166 18.34635 84.34087  1.000 30.78727 ? 101 ASP A CG  1 
ATOM   765  O OD1 . ASP A 1 102 ? 70.42333 18.74794 83.60103  1.000 32.45092 ? 101 ASP A OD1 1 
ATOM   766  O OD2 . ASP A 1 102 ? 69.68425 17.43740 85.16296  1.000 29.53501 ? 101 ASP A OD2 1 
ATOM   767  N N   . PHE A 1 103 ? 69.96324 20.99533 82.37439  1.000 29.75977 ? 102 PHE A N   1 
ATOM   768  C CA  . PHE A 1 103 ? 70.56649 21.14092 81.05065  1.000 30.30734 ? 102 PHE A CA  1 
ATOM   769  C C   . PHE A 1 103 ? 70.43498 19.89076 80.18325  1.000 35.79961 ? 102 PHE A C   1 
ATOM   770  O O   . PHE A 1 103 ? 70.38268 20.00062 78.95157  1.000 38.51564 ? 102 PHE A O   1 
ATOM   771  C CB  . PHE A 1 103 ? 72.03916 21.48952 81.18516  1.000 30.06352 ? 102 PHE A CB  1 
ATOM   772  C CG  . PHE A 1 103 ? 72.63427 22.06714 79.93853  1.000 37.99515 ? 102 PHE A CG  1 
ATOM   773  C CD1 . PHE A 1 103 ? 72.33068 23.36546 79.54195  1.000 38.03140 ? 102 PHE A CD1 1 
ATOM   774  C CD2 . PHE A 1 103 ? 73.49339 21.31145 79.14807  1.000 35.76261 ? 102 PHE A CD2 1 
ATOM   775  C CE1 . PHE A 1 103 ? 72.88866 23.90572 78.39002  1.000 33.83253 ? 102 PHE A CE1 1 
ATOM   776  C CE2 . PHE A 1 103 ? 74.05143 21.84894 77.98895  1.000 32.53402 ? 102 PHE A CE2 1 
ATOM   777  C CZ  . PHE A 1 103 ? 73.75009 23.14530 77.61865  1.000 33.84548 ? 102 PHE A CZ  1 
ATOM   778  N N   . TYR A 1 104 ? 70.38059 18.70735 80.78766  1.000 29.29956 ? 103 TYR A N   1 
ATOM   779  C CA  . TYR A 1 104 ? 70.28594 17.45483 80.05377  1.000 26.16481 ? 103 TYR A CA  1 
ATOM   780  C C   . TYR A 1 104 ? 69.01801 16.69553 80.41231  1.000 28.41061 ? 103 TYR A C   1 
ATOM   781  O O   . TYR A 1 104 ? 68.34235 16.99449 81.39602  1.000 33.17418 ? 103 TYR A O   1 
ATOM   782  C CB  . TYR A 1 104 ? 71.46598 16.55743 80.37007  1.000 31.79173 ? 103 TYR A CB  1 
ATOM   783  C CG  . TYR A 1 104 ? 72.78647 17.24645 80.37415  1.000 32.66407 ? 103 TYR A CG  1 
ATOM   784  C CD1 . TYR A 1 104 ? 73.50387 17.40168 79.20935  1.000 30.23584 ? 103 TYR A CD1 1 
ATOM   785  C CD2 . TYR A 1 104 ? 73.31853 17.74157 81.54749  1.000 32.54879 ? 103 TYR A CD2 1 
ATOM   786  C CE1 . TYR A 1 104 ? 74.72295 18.00474 79.21313  1.000 32.18113 ? 103 TYR A CE1 1 
ATOM   787  C CE2 . TYR A 1 104 ? 74.53164 18.35892 81.56106  1.000 33.49136 ? 103 TYR A CE2 1 
ATOM   788  C CZ  . TYR A 1 104 ? 75.23532 18.48669 80.39101  1.000 34.58454 ? 103 TYR A CZ  1 
ATOM   789  O OH  . TYR A 1 104 ? 76.46294 19.10549 80.40246  1.000 39.84894 ? 103 TYR A OH  1 
ATOM   790  N N   . ASP A 1 105 ? 68.73059 15.66230 79.62487  1.000 28.59607 ? 104 ASP A N   1 
ATOM   791  C CA  . ASP A 1 105 ? 67.69362 14.70231 79.97965  1.000 29.73430 ? 104 ASP A CA  1 
ATOM   792  C C   . ASP A 1 105 ? 68.25453 13.62397 80.90966  1.000 32.84722 ? 104 ASP A C   1 
ATOM   793  O O   . ASP A 1 105 ? 69.47318 13.49042 81.08872  1.000 29.75111 ? 104 ASP A O   1 
ATOM   794  C CB  . ASP A 1 105 ? 67.09910 14.04742 78.73604  1.000 29.79536 ? 104 ASP A CB  1 
ATOM   795  C CG  . ASP A 1 105 ? 68.15871 13.57395 77.75528  1.000 31.50420 ? 104 ASP A CG  1 
ATOM   796  O OD1 . ASP A 1 105 ? 69.27704 13.20069 78.17468  1.000 31.85659 ? 104 ASP A OD1 1 
ATOM   797  O OD2 . ASP A 1 105 ? 67.86276 13.57102 76.54775  1.000 31.94452 ? 104 ASP A OD2 1 
ATOM   798  N N   . PHE A 1 106 ? 67.34644 12.79433 81.44952  1.000 30.14820 ? 105 PHE A N   1 
ATOM   799  C CA  . PHE A 1 106 ? 67.73777 11.86856 82.50878  1.000 29.23312 ? 105 PHE A CA  1 
ATOM   800  C C   . PHE A 1 106 ? 68.76719 10.87790 82.02093  1.000 30.63757 ? 105 PHE A C   1 
ATOM   801  O O   . PHE A 1 106 ? 69.45590 10.25300 82.83301  1.000 29.73777 ? 105 PHE A O   1 
ATOM   802  C CB  . PHE A 1 106 ? 66.51925 11.14962 83.10233  1.000 32.05953 ? 105 PHE A CB  1 
ATOM   803  C CG  . PHE A 1 106 ? 65.78762 10.28142 82.13808  1.000 33.56129 ? 105 PHE A CG  1 
ATOM   804  C CD1 . PHE A 1 106 ? 66.22184 8.98914  81.88155  1.000 36.50630 ? 105 PHE A CD1 1 
ATOM   805  C CD2 . PHE A 1 106 ? 64.64080 10.73795 81.51461  1.000 33.21825 ? 105 PHE A CD2 1 
ATOM   806  C CE1 . PHE A 1 106 ? 65.54724 8.18516  80.98572  1.000 36.48358 ? 105 PHE A CE1 1 
ATOM   807  C CE2 . PHE A 1 106 ? 63.95797 9.94021  80.62592  1.000 35.28963 ? 105 PHE A CE2 1 
ATOM   808  C CZ  . PHE A 1 106 ? 64.41100 8.65886  80.36177  1.000 38.05400 ? 105 PHE A CZ  1 
ATOM   809  N N   . TRP A 1 107 ? 68.87792 10.72399 80.70653  1.000 34.03316 ? 106 TRP A N   1 
ATOM   810  C CA  . TRP A 1 107 ? 69.86510 9.81431  80.15318  1.000 37.22804 ? 106 TRP A CA  1 
ATOM   811  C C   . TRP A 1 107 ? 71.27623 10.20598 80.57735  1.000 38.87655 ? 106 TRP A C   1 
ATOM   812  O O   . TRP A 1 107 ? 72.05767 9.35430  81.01460  1.000 36.94957 ? 106 TRP A O   1 
ATOM   813  C CB  . TRP A 1 107 ? 69.76830 9.82651  78.62756  1.000 35.05054 ? 106 TRP A CB  1 
ATOM   814  C CG  . TRP A 1 107 ? 68.43744 9.43741  78.05199  1.000 37.20706 ? 106 TRP A CG  1 
ATOM   815  C CD1 . TRP A 1 107 ? 67.60925 10.22247 77.29199  1.000 35.84223 ? 106 TRP A CD1 1 
ATOM   816  C CD2 . TRP A 1 107 ? 67.79329 8.15465  78.15109  1.000 42.15124 ? 106 TRP A CD2 1 
ATOM   817  N NE1 . TRP A 1 107 ? 66.48290 9.51204  76.92332  1.000 42.40858 ? 106 TRP A NE1 1 
ATOM   818  C CE2 . TRP A 1 107 ? 66.57075 8.24140  77.43545  1.000 47.22544 ? 106 TRP A CE2 1 
ATOM   819  C CE3 . TRP A 1 107 ? 68.12353 6.95097  78.77859  1.000 31.37163 ? 106 TRP A CE3 1 
ATOM   820  C CZ2 . TRP A 1 107 ? 65.68418 7.16618  77.33347  1.000 33.90513 ? 106 TRP A CZ2 1 
ATOM   821  C CZ3 . TRP A 1 107 ? 67.24557 5.89617  78.68099  1.000 34.70603 ? 106 TRP A CZ3 1 
ATOM   822  C CH2 . TRP A 1 107 ? 66.03891 6.00692  77.95829  1.000 35.73528 ? 106 TRP A CH2 1 
ATOM   823  N N   . ASN A 1 108 ? 71.58045 11.50374 80.56183  1.000 41.85055 ? 107 ASN A N   1 
ATOM   824  C CA  . ASN A 1 108 ? 72.96362 11.95849 80.48822  1.000 37.46256 ? 107 ASN A CA  1 
ATOM   825  C C   . ASN A 1 108 ? 73.67429 11.79200 81.82456  1.000 39.29814 ? 107 ASN A C   1 
ATOM   826  O O   . ASN A 1 108 ? 73.06170 11.82400 82.89946  1.000 35.79939 ? 107 ASN A O   1 
ATOM   827  C CB  . ASN A 1 108 ? 73.04271 13.41875 80.02082  1.000 36.37687 ? 107 ASN A CB  1 
ATOM   828  C CG  . ASN A 1 108 ? 74.42726 13.79466 79.46541  1.000 38.13985 ? 107 ASN A CG  1 
ATOM   829  O OD1 . ASN A 1 108 ? 75.30070 14.25663 80.19730  1.000 36.92251 ? 107 ASN A OD1 1 
ATOM   830  N ND2 . ASN A 1 108 ? 74.62375 13.58878 78.16793  1.000 39.44275 ? 107 ASN A ND2 1 
ATOM   831  N N   . GLU A 1 109 ? 74.97902 11.52480 81.72855  1.000 38.96809 ? 108 GLU A N   1 
ATOM   832  C CA  . GLU A 1 109 ? 75.80622 11.37398 82.91628  1.000 36.17616 ? 108 GLU A CA  1 
ATOM   833  C C   . GLU A 1 109 ? 75.80861 12.63420 83.76207  1.000 38.81343 ? 108 GLU A C   1 
ATOM   834  O O   . GLU A 1 109 ? 75.74486 12.56397 84.99512  1.000 33.00798 ? 108 GLU A O   1 
ATOM   835  C CB  . GLU A 1 109 ? 77.23120 11.04475 82.49404  1.000 37.57657 ? 108 GLU A CB  1 
ATOM   836  C CG  . GLU A 1 109 ? 78.24614 11.30643 83.56867  1.000 39.26742 ? 108 GLU A CG  1 
ATOM   837  C CD  . GLU A 1 109 ? 79.66533 11.01447 83.11615  1.000 50.78832 ? 108 GLU A CD  1 
ATOM   838  O OE1 . GLU A 1 109 ? 79.89331 10.73298 81.90889  1.000 41.94111 ? 108 GLU A OE1 1 
ATOM   839  O OE2 . GLU A 1 109 ? 80.55176 11.04462 83.99647  1.000 55.03878 ? 108 GLU A OE2 1 
ATOM   840  N N   . PHE A 1 110 ? 75.83790 13.79796 83.10845  1.000 42.28265 ? 109 PHE A N   1 
ATOM   841  C CA  . PHE A 1 110 ? 75.99065 15.09662 83.74988  1.000 37.84613 ? 109 PHE A CA  1 
ATOM   842  C C   . PHE A 1 110 ? 74.66909 15.70413 84.14709  1.000 33.34169 ? 109 PHE A C   1 
ATOM   843  O O   . PHE A 1 110 ? 74.58625 16.92310 84.32504  1.000 34.65422 ? 109 PHE A O   1 
ATOM   844  C CB  . PHE A 1 110 ? 76.76244 16.04559 82.84093  1.000 35.50637 ? 109 PHE A CB  1 
ATOM   845  C CG  . PHE A 1 110 ? 78.11346 15.54094 82.46668  1.000 38.87252 ? 109 PHE A CG  1 
ATOM   846  C CD1 . PHE A 1 110 ? 78.55219 15.60585 81.15076  1.000 38.57049 ? 109 PHE A CD1 1 
ATOM   847  C CD2 . PHE A 1 110 ? 78.94349 14.98491 83.42826  1.000 38.39905 ? 109 PHE A CD2 1 
ATOM   848  C CE1 . PHE A 1 110 ? 79.79826 15.13800 80.80056  1.000 38.01444 ? 109 PHE A CE1 1 
ATOM   849  C CE2 . PHE A 1 110 ? 80.19354 14.50976 83.09013  1.000 41.62867 ? 109 PHE A CE2 1 
ATOM   850  C CZ  . PHE A 1 110 ? 80.62637 14.59113 81.77500  1.000 45.97740 ? 109 PHE A CZ  1 
ATOM   851  N N   . SER A 1 111 ? 73.61723 14.90199 84.18546  1.000 29.87805 ? 110 SER A N   1 
ATOM   852  C CA  . SER A 1 111 ? 72.32797 15.38792 84.61627  1.000 32.72070 ? 110 SER A CA  1 
ATOM   853  C C   . SER A 1 111 ? 72.36902 15.79901 86.09047  1.000 35.00630 ? 110 SER A C   1 
ATOM   854  O O   . SER A 1 111 ? 73.33184 15.53613 86.82063  1.000 34.03562 ? 110 SER A O   1 
ATOM   855  C CB  . SER A 1 111 ? 71.27984 14.30923 84.41742  1.000 33.06577 ? 110 SER A CB  1 
ATOM   856  O OG  . SER A 1 111 ? 71.72102 13.13079 85.04458  1.000 34.46825 ? 110 SER A OG  1 
ATOM   857  N N   . HIS A 1 112 ? 71.30653 16.49588 86.50667  1.000 34.80699 ? 111 HIS A N   1 
ATOM   858  C CA  . HIS A 1 112 ? 71.10607 16.94487 87.89127  1.000 34.05855 ? 111 HIS A CA  1 
ATOM   859  C C   . HIS A 1 112 ? 72.22504 17.85753 88.39662  1.000 34.18035 ? 111 HIS A C   1 
ATOM   860  O O   . HIS A 1 112 ? 72.50732 17.89763 89.60037  1.000 34.88960 ? 111 HIS A O   1 
ATOM   861  C CB  . HIS A 1 112 ? 70.90478 15.75206 88.82995  1.000 30.79660 ? 111 HIS A CB  1 
ATOM   862  C CG  . HIS A 1 112 ? 70.00257 14.69863 88.27104  1.000 29.71737 ? 111 HIS A CG  1 
ATOM   863  N ND1 . HIS A 1 112 ? 70.27775 13.35272 88.36452  1.000 38.46261 ? 111 HIS A ND1 1 
ATOM   864  C CD2 . HIS A 1 112 ? 68.84569 14.79816 87.57661  1.000 29.39686 ? 111 HIS A CD2 1 
ATOM   865  C CE1 . HIS A 1 112 ? 69.31811 12.66804 87.76945  1.000 38.40260 ? 111 HIS A CE1 1 
ATOM   866  N NE2 . HIS A 1 112 ? 68.43549 13.52281 87.28560  1.000 32.96590 ? 111 HIS A NE2 1 
ATOM   867  N N   . ARG A 1 113 ? 72.85689 18.61482 87.48735  1.000 36.92421 ? 112 ARG A N   1 
ATOM   868  C CA  . ARG A 1 113 ? 73.98609 19.46901 87.83836  1.000 34.42263 ? 112 ARG A CA  1 
ATOM   869  C C   . ARG A 1 113 ? 73.82986 20.89610 87.36086  1.000 31.60789 ? 112 ARG A C   1 
ATOM   870  O O   . ARG A 1 113 ? 74.25309 21.81174 88.05146  1.000 37.97409 ? 112 ARG A O   1 
ATOM   871  C CB  . ARG A 1 113 ? 75.28802 18.89925 87.27656  1.000 37.04578 ? 112 ARG A CB  1 
ATOM   872  C CG  . ARG A 1 113 ? 75.69222 17.63156 87.97317  1.000 41.45623 ? 112 ARG A CG  1 
ATOM   873  C CD  . ARG A 1 113 ? 75.57074 17.79030 89.46966  1.000 37.96523 ? 112 ARG A CD  1 
ATOM   874  N NE  . ARG A 1 113 ? 75.94687 16.56589 90.16503  1.000 42.52158 ? 112 ARG A NE  1 
ATOM   875  C CZ  . ARG A 1 113 ? 75.10290 15.77473 90.82116  1.000 37.14746 ? 112 ARG A CZ  1 
ATOM   876  N NH1 . ARG A 1 113 ? 73.81143 16.08375 90.90159  1.000 31.81039 ? 112 ARG A NH1 1 
ATOM   877  N NH2 . ARG A 1 113 ? 75.56947 14.69046 91.42592  1.000 33.10379 ? 112 ARG A NH2 1 
ATOM   878  N N   . THR A 1 114 ? 73.26143 21.11080 86.19675  1.000 30.97928 ? 113 THR A N   1 
ATOM   879  C CA  . THR A 1 114 ? 73.20620 22.44251 85.62622  1.000 29.35575 ? 113 THR A CA  1 
ATOM   880  C C   . THR A 1 114 ? 71.78500 22.72900 85.18294  1.000 30.63695 ? 113 THR A C   1 
ATOM   881  O O   . THR A 1 114 ? 71.08456 21.83913 84.70165  1.000 32.43265 ? 113 THR A O   1 
ATOM   882  C CB  . THR A 1 114 ? 74.19341 22.58728 84.45980  1.000 32.00050 ? 113 THR A CB  1 
ATOM   883  O OG1 . THR A 1 114 ? 75.51556 22.29890 84.92641  1.000 34.31428 ? 113 THR A OG1 1 
ATOM   884  C CG2 . THR A 1 114 ? 74.18066 24.00080 83.90392  1.000 34.55855 ? 113 THR A CG2 1 
ATOM   885  N N   . PHE A 1 115 ? 71.33549 23.94966 85.40165  1.000 33.71961 ? 114 PHE A N   1 
ATOM   886  C CA  . PHE A 1 115 ? 69.96833 24.30444 85.07755  1.000 28.86347 ? 114 PHE A CA  1 
ATOM   887  C C   . PHE A 1 115 ? 69.94904 25.50445 84.15312  1.000 33.11781 ? 114 PHE A C   1 
ATOM   888  O O   . PHE A 1 115 ? 70.80609 26.38604 84.25084  1.000 38.48823 ? 114 PHE A O   1 
ATOM   889  C CB  . PHE A 1 115 ? 69.19707 24.56978 86.33457  1.000 23.40548 ? 114 PHE A CB  1 
ATOM   890  C CG  . PHE A 1 115 ? 69.12235 23.39088 87.19668  1.000 27.95438 ? 114 PHE A CG  1 
ATOM   891  C CD1 . PHE A 1 115 ? 68.07965 22.48864 87.04864  1.000 30.01984 ? 114 PHE A CD1 1 
ATOM   892  C CD2 . PHE A 1 115 ? 70.12495 23.12465 88.09989  1.000 29.15127 ? 114 PHE A CD2 1 
ATOM   893  C CE1 . PHE A 1 115 ? 68.01281 21.36579 87.80364  1.000 24.98378 ? 114 PHE A CE1 1 
ATOM   894  C CE2 . PHE A 1 115 ? 70.06406 21.99253 88.87678  1.000 34.97701 ? 114 PHE A CE2 1 
ATOM   895  C CZ  . PHE A 1 115 ? 69.00436 21.10925 88.72395  1.000 33.34077 ? 114 PHE A CZ  1 
ATOM   896  N N   . ASP A 1 116 ? 68.98930 25.50614 83.23120  1.000 31.59455 ? 115 ASP A N   1 
ATOM   897  C CA  . ASP A 1 116 ? 68.90695 26.50068 82.17394  1.000 32.10390 ? 115 ASP A CA  1 
ATOM   898  C C   . ASP A 1 116 ? 67.43125 26.79358 81.90657  1.000 25.41191 ? 115 ASP A C   1 
ATOM   899  O O   . ASP A 1 116 ? 66.54058 26.28711 82.58939  1.000 25.63698 ? 115 ASP A O   1 
ATOM   900  C CB  . ASP A 1 116 ? 69.67005 26.01758 80.93053  1.000 36.46745 ? 115 ASP A CB  1 
ATOM   901  C CG  . ASP A 1 116 ? 69.95363 27.13003 79.93585  1.000 37.98997 ? 115 ASP A CG  1 
ATOM   902  O OD1 . ASP A 1 116 ? 70.05384 28.30924 80.35189  1.000 35.63538 ? 115 ASP A OD1 1 
ATOM   903  O OD2 . ASP A 1 116 ? 70.07851 26.80805 78.73102  1.000 40.91828 ? 115 ASP A OD2 1 
ATOM   904  N N   . PHE A 1 117 ? 67.17383 27.63223 80.91246  1.000 28.66675 ? 116 PHE A N   1 
ATOM   905  C CA  . PHE A 1 117 ? 65.81642 27.92315 80.44738  1.000 33.55284 ? 116 PHE A CA  1 
ATOM   906  C C   . PHE A 1 117 ? 64.92434 28.44544 81.57664  1.000 32.06050 ? 116 PHE A C   1 
ATOM   907  O O   . PHE A 1 117 ? 63.71953 28.18910 81.60224  1.000 34.01085 ? 116 PHE A O   1 
ATOM   908  C CB  . PHE A 1 117 ? 65.21512 26.70074 79.74138  1.000 30.35471 ? 116 PHE A CB  1 
ATOM   909  C CG  . PHE A 1 117 ? 66.11475 26.15789 78.65685  1.000 34.06915 ? 116 PHE A CG  1 
ATOM   910  C CD1 . PHE A 1 117 ? 66.32576 26.88148 77.48633  1.000 31.82346 ? 116 PHE A CD1 1 
ATOM   911  C CD2 . PHE A 1 117 ? 66.82039 24.97092 78.83992  1.000 34.87345 ? 116 PHE A CD2 1 
ATOM   912  C CE1 . PHE A 1 117 ? 67.19646 26.40529 76.49233  1.000 35.09747 ? 116 PHE A CE1 1 
ATOM   913  C CE2 . PHE A 1 117 ? 67.69689 24.49290 77.85155  1.000 37.89910 ? 116 PHE A CE2 1 
ATOM   914  C CZ  . PHE A 1 117 ? 67.87849 25.20852 76.67259  1.000 32.93334 ? 116 PHE A CZ  1 
ATOM   915  N N   . TRP A 1 118 ? 65.51759 29.18823 82.51565  1.000 21.38327 ? 117 TRP A N   1 
ATOM   916  C CA  . TRP A 1 118 ? 64.74390 29.82891 83.56351  1.000 25.18357 ? 117 TRP A CA  1 
ATOM   917  C C   . TRP A 1 118 ? 63.63211 30.69048 82.96743  1.000 30.92109 ? 117 TRP A C   1 
ATOM   918  O O   . TRP A 1 118 ? 63.80106 31.30188 81.90533  1.000 30.87588 ? 117 TRP A O   1 
ATOM   919  C CB  . TRP A 1 118 ? 65.64436 30.69393 84.44432  1.000 26.24888 ? 117 TRP A CB  1 
ATOM   920  C CG  . TRP A 1 118 ? 66.73179 29.98153 85.20787  1.000 26.85631 ? 117 TRP A CG  1 
ATOM   921  C CD1 . TRP A 1 118 ? 67.52592 28.97154 84.76889  1.000 27.11898 ? 117 TRP A CD1 1 
ATOM   922  C CD2 . TRP A 1 118 ? 67.14453 30.25590 86.55266  1.000 28.77209 ? 117 TRP A CD2 1 
ATOM   923  N NE1 . TRP A 1 118 ? 68.40448 28.59237 85.75384  1.000 24.40254 ? 117 TRP A NE1 1 
ATOM   924  C CE2 . TRP A 1 118 ? 68.19347 29.37488 86.85578  1.000 26.13495 ? 117 TRP A CE2 1 
ATOM   925  C CE3 . TRP A 1 118 ? 66.72096 31.16434 87.53211  1.000 29.82678 ? 117 TRP A CE3 1 
ATOM   926  C CZ2 . TRP A 1 118 ? 68.82649 29.37493 88.09047  1.000 31.17557 ? 117 TRP A CZ2 1 
ATOM   927  C CZ3 . TRP A 1 118 ? 67.35160 31.16846 88.75415  1.000 25.03122 ? 117 TRP A CZ3 1 
ATOM   928  C CH2 . TRP A 1 118 ? 68.39152 30.27929 89.02515  1.000 31.62585 ? 117 TRP A CH2 1 
ATOM   929  N N   . GLY A 1 119 ? 62.46453 30.68825 83.62700  1.000 28.55088 ? 118 GLY A N   1 
ATOM   930  C CA  . GLY A 1 119 ? 61.36567 31.54305 83.22745  1.000 31.08343 ? 118 GLY A CA  1 
ATOM   931  C C   . GLY A 1 119 ? 61.60163 32.95883 83.71610  1.000 32.01405 ? 118 GLY A C   1 
ATOM   932  O O   . GLY A 1 119 ? 62.62309 33.26458 84.32279  1.000 33.09559 ? 118 GLY A O   1 
ATOM   933  N N   . GLN A 1 120 ? 60.60182 33.82714 83.53012  1.000 36.64292 ? 119 GLN A N   1 
ATOM   934  C CA  . GLN A 1 120 ? 60.73152 35.16662 84.10620  1.000 33.93141 ? 119 GLN A CA  1 
ATOM   935  C C   . GLN A 1 120 ? 60.65029 35.13819 85.62243  1.000 26.57553 ? 119 GLN A C   1 
ATOM   936  O O   . GLN A 1 120 ? 61.30146 35.93969 86.29068  1.000 24.95425 ? 119 GLN A O   1 
ATOM   937  C CB  . GLN A 1 120 ? 59.63679 36.10074 83.58230  1.000 35.33502 ? 119 GLN A CB  1 
ATOM   938  C CG  . GLN A 1 120 ? 60.00257 37.00067 82.39728  1.000 49.48701 ? 119 GLN A CG  1 
ATOM   939  C CD  . GLN A 1 120 ? 59.76405 36.37069 81.03952  1.000 50.41200 ? 119 GLN A CD  1 
ATOM   940  O OE1 . GLN A 1 120 ? 59.12919 35.31839 80.93020  1.000 53.17319 ? 119 GLN A OE1 1 
ATOM   941  N NE2 . GLN A 1 120 ? 60.24516 37.03721 79.98695  1.000 35.87013 ? 119 GLN A NE2 1 
ATOM   942  N N   . GLY A 1 121 ? 59.92760 34.18397 86.18026  1.000 31.54249 ? 120 GLY A N   1 
ATOM   943  C CA  . GLY A 1 121 ? 59.67096 34.17250 87.60181  1.000 31.96215 ? 120 GLY A CA  1 
ATOM   944  C C   . GLY A 1 121 ? 58.38094 34.89154 87.95775  1.000 29.75080 ? 120 GLY A C   1 
ATOM   945  O O   . GLY A 1 121 ? 57.92938 35.80996 87.27742  1.000 37.14318 ? 120 GLY A O   1 
ATOM   946  N N   . THR A 1 122 ? 57.84294 34.54149 89.10725  1.000 28.62254 ? 121 THR A N   1 
ATOM   947  C CA  . THR A 1 122 ? 56.66096 35.21214 89.60823  1.000 21.56742 ? 121 THR A CA  1 
ATOM   948  C C   . THR A 1 122 ? 56.96842 35.68447 91.01456  1.000 25.91546 ? 121 THR A C   1 
ATOM   949  O O   . THR A 1 122 ? 57.65040 34.99544 91.77648  1.000 28.81316 ? 121 THR A O   1 
ATOM   950  C CB  . THR A 1 122 ? 55.43342 34.30190 89.55897  1.000 23.28078 ? 121 THR A CB  1 
ATOM   951  O OG1 . THR A 1 122 ? 54.26285 35.04672 89.89478  1.000 32.56281 ? 121 THR A OG1 1 
ATOM   952  C CG2 . THR A 1 122 ? 55.56211 33.16149 90.51333  1.000 27.23969 ? 121 THR A CG2 1 
ATOM   953  N N   . LEU A 1 123 ? 56.60648 36.93381 91.28560  1.000 30.88477 ? 122 LEU A N   1 
ATOM   954  C CA  . LEU A 1 123 ? 56.96791 37.58664 92.53475  1.000 27.36555 ? 122 LEU A CA  1 
ATOM   955  C C   . LEU A 1 123 ? 56.00298 37.17281 93.64226  1.000 28.37225 ? 122 LEU A C   1 
ATOM   956  O O   . LEU A 1 123 ? 54.77754 37.21558 93.46208  1.000 25.52914 ? 122 LEU A O   1 
ATOM   957  C CB  . LEU A 1 123 ? 56.96308 39.10430 92.35656  1.000 22.43109 ? 122 LEU A CB  1 
ATOM   958  C CG  . LEU A 1 123 ? 57.28174 39.94086 93.60121  1.000 27.68439 ? 122 LEU A CG  1 
ATOM   959  C CD1 . LEU A 1 123 ? 58.49954 39.41038 94.33971  1.000 26.36504 ? 122 LEU A CD1 1 
ATOM   960  C CD2 . LEU A 1 123 ? 57.49968 41.39381 93.21518  1.000 30.51371 ? 122 LEU A CD2 1 
ATOM   961  N N   . VAL A 1 124 ? 56.56086 36.78233 94.78985  1.000 28.91512 ? 123 VAL A N   1 
ATOM   962  C CA  . VAL A 1 124 ? 55.78948 36.50937 95.99669  1.000 29.46263 ? 123 VAL A CA  1 
ATOM   963  C C   . VAL A 1 124 ? 56.24493 37.48851 97.06607  1.000 32.61858 ? 123 VAL A C   1 
ATOM   964  O O   . VAL A 1 124 ? 57.41292 37.46742 97.48434  1.000 31.85685 ? 123 VAL A O   1 
ATOM   965  C CB  . VAL A 1 124 ? 55.94387 35.05080 96.46765  1.000 27.91833 ? 123 VAL A CB  1 
ATOM   966  C CG1 . VAL A 1 124 ? 55.11052 34.80627 97.71261  1.000 21.88284 ? 123 VAL A CG1 1 
ATOM   967  C CG2 . VAL A 1 124 ? 55.52469 34.08290 95.34550  1.000 27.95391 ? 123 VAL A CG2 1 
ATOM   968  N N   . THR A 1 125 ? 55.31985 38.34608 97.49351  1.000 31.75982 ? 124 THR A N   1 
ATOM   969  C CA  . THR A 1 125 ? 55.51810 39.32003 98.55706  1.000 31.51906 ? 124 THR A CA  1 
ATOM   970  C C   . THR A 1 125 ? 54.62106 38.91584 99.72063  1.000 35.26910 ? 124 THR A C   1 
ATOM   971  O O   . THR A 1 125 ? 53.42552 38.65023 99.52423  1.000 31.39783 ? 124 THR A O   1 
ATOM   972  C CB  . THR A 1 125 ? 55.17250 40.73824 98.06370  1.000 33.27614 ? 124 THR A CB  1 
ATOM   973  O OG1 . THR A 1 125 ? 55.97175 41.06510 96.91822  1.000 38.80707 ? 124 THR A OG1 1 
ATOM   974  C CG2 . THR A 1 125 ? 55.41942 41.78070 99.13079  1.000 31.21269 ? 124 THR A CG2 1 
ATOM   975  N N   . VAL A 1 126 ? 55.17426 38.90564 100.93119 1.000 33.55401 ? 125 VAL A N   1 
ATOM   976  C CA  . VAL A 1 126 ? 54.43371 38.47060 102.10564 1.000 30.27541 ? 125 VAL A CA  1 
ATOM   977  C C   . VAL A 1 126 ? 54.38347 39.64648 103.07830 1.000 36.29818 ? 125 VAL A C   1 
ATOM   978  O O   . VAL A 1 126 ? 55.43330 40.10245 103.54820 1.000 43.43822 ? 125 VAL A O   1 
ATOM   979  C CB  . VAL A 1 126 ? 55.10260 37.25290 102.75040 1.000 37.30845 ? 125 VAL A CB  1 
ATOM   980  C CG1 . VAL A 1 126 ? 54.24459 36.71876 103.89203 1.000 42.82836 ? 125 VAL A CG1 1 
ATOM   981  C CG2 . VAL A 1 126 ? 55.48336 36.19022 101.69103 1.000 33.64102 ? 125 VAL A CG2 1 
ATOM   982  N N   . SER A 1 127 ? 53.16955 40.08887 103.43234 1.000 37.45934 ? 126 SER A N   1 
ATOM   983  C CA  . SER A 1 127 ? 52.95151 41.35938 104.12960 1.000 31.27122 ? 126 SER A CA  1 
ATOM   984  C C   . SER A 1 127 ? 53.64426 41.40703 105.48717 1.000 35.43581 ? 126 SER A C   1 
ATOM   985  O O   . SER A 1 127 ? 54.18127 40.42082 105.98648 1.000 42.66032 ? 126 SER A O   1 
ATOM   986  C CB  . SER A 1 127 ? 51.46265 41.61752 104.35705 1.000 31.41690 ? 126 SER A CB  1 
ATOM   987  O OG  . SER A 1 127 ? 50.70096 41.37362 103.18891 1.000 34.02007 ? 126 SER A OG  1 
ATOM   988  N N   . SER A 1 128 ? 53.60720 42.59423 106.08422 1.000 45.15756 ? 127 SER A N   1 
ATOM   989  C CA  . SER A 1 128 ? 54.10734 42.83776 107.43441 1.000 47.26563 ? 127 SER A CA  1 
ATOM   990  C C   . SER A 1 128 ? 55.58601 42.49354 107.59716 1.000 54.12588 ? 127 SER A C   1 
ATOM   991  O O   . SER A 1 128 ? 55.96614 41.76205 108.51883 1.000 59.65464 ? 127 SER A O   1 
ATOM   992  C CB  . SER A 1 128 ? 53.27572 42.04572 108.44269 1.000 49.03011 ? 127 SER A CB  1 
ATOM   993  O OG  . SER A 1 128 ? 51.89748 42.21159 108.17490 1.000 48.75658 ? 127 SER A OG  1 
ATOM   994  N N   . ALA A 1 151 ? 77.11103 32.41942 100.19038 1.000 30.72685 ? 150 ALA A N   1 
ATOM   995  C CA  . ALA A 1 151 ? 77.92601 31.26135 100.55100 1.000 40.09810 ? 150 ALA A CA  1 
ATOM   996  C C   . ALA A 1 151 ? 79.11774 31.03988 99.58878  1.000 45.57010 ? 150 ALA A C   1 
ATOM   997  O O   . ALA A 1 151 ? 80.05542 30.29357 99.91556  1.000 46.27414 ? 150 ALA A O   1 
ATOM   998  C CB  . ALA A 1 151 ? 77.05267 30.00095 100.62291 1.000 29.39047 ? 150 ALA A CB  1 
ATOM   999  N N   . LEU A 1 152 ? 79.05589 31.61311 98.38640  1.000 34.34065 ? 151 LEU A N   1 
ATOM   1000 C CA  . LEU A 1 152 ? 80.23347 31.75668 97.54376  1.000 34.22934 ? 151 LEU A CA  1 
ATOM   1001 C C   . LEU A 1 152 ? 80.55534 33.23798 97.47300  1.000 40.61982 ? 151 LEU A C   1 
ATOM   1002 O O   . LEU A 1 152 ? 79.65361 34.07800 97.46733  1.000 43.08235 ? 151 LEU A O   1 
ATOM   1003 C CB  . LEU A 1 152 ? 80.02637 31.19842 96.14062  1.000 31.87124 ? 151 LEU A CB  1 
ATOM   1004 C CG  . LEU A 1 152 ? 79.35201 29.84000 96.02085  1.000 36.04232 ? 151 LEU A CG  1 
ATOM   1005 C CD1 . LEU A 1 152 ? 78.85795 29.59406 94.58910  1.000 35.25291 ? 151 LEU A CD1 1 
ATOM   1006 C CD2 . LEU A 1 152 ? 80.31172 28.74758 96.45904  1.000 40.79175 ? 151 LEU A CD2 1 
ATOM   1007 N N   . THR A 1 153 ? 81.83545 33.56670 97.41567  1.000 41.75651 ? 152 THR A N   1 
ATOM   1008 C CA  . THR A 1 153 ? 82.24979 34.95334 97.56466  1.000 41.06564 ? 152 THR A CA  1 
ATOM   1009 C C   . THR A 1 153 ? 82.45466 35.61492 96.21339  1.000 33.84892 ? 152 THR A C   1 
ATOM   1010 O O   . THR A 1 153 ? 83.19834 35.11813 95.36521  1.000 32.88023 ? 152 THR A O   1 
ATOM   1011 C CB  . THR A 1 153 ? 83.51443 35.06070 98.40759  1.000 46.70017 ? 152 THR A CB  1 
ATOM   1012 O OG1 . THR A 1 153 ? 83.36144 34.24295 99.57667  1.000 48.27475 ? 152 THR A OG1 1 
ATOM   1013 C CG2 . THR A 1 153 ? 83.72717 36.51432 98.82662  1.000 41.31305 ? 152 THR A CG2 1 
ATOM   1014 N N   . GLN A 1 154 ? 81.84752 36.75466 96.05660  1.000 33.34120 ? 153 GLN A N   1 
ATOM   1015 C CA  . GLN A 1 154 ? 81.76245 37.37017 94.75849  1.000 34.14327 ? 153 GLN A CA  1 
ATOM   1016 C C   . GLN A 1 154 ? 81.91446 38.88560 94.89449  1.000 38.34130 ? 153 GLN A C   1 
ATOM   1017 O O   . GLN A 1 154 ? 81.13507 39.53675 95.60701  1.000 28.62827 ? 153 GLN A O   1 
ATOM   1018 C CB  . GLN A 1 154 ? 80.42913 36.92939 94.17315  1.000 35.29776 ? 153 GLN A CB  1 
ATOM   1019 C CG  . GLN A 1 154 ? 80.09994 37.37049 92.81695  1.000 39.22255 ? 153 GLN A CG  1 
ATOM   1020 C CD  . GLN A 1 154 ? 79.15528 36.40718 92.13895  1.000 34.75054 ? 153 GLN A CD  1 
ATOM   1021 O OE1 . GLN A 1 154 ? 78.38161 35.70208 92.78824  1.000 31.30545 ? 153 GLN A OE1 1 
ATOM   1022 N NE2 . GLN A 1 154 ? 79.19318 36.39408 90.82213  1.000 40.76320 ? 153 GLN A NE2 1 
ATOM   1023 N N   . PRO A 1 155 ? 82.88602 39.48141 94.20208  1.000 36.19930 ? 154 PRO A N   1 
ATOM   1024 C CA  . PRO A 1 155 ? 83.11801 40.92328 94.34500  1.000 35.26479 ? 154 PRO A CA  1 
ATOM   1025 C C   . PRO A 1 155 ? 81.88508 41.71825 93.94634  1.000 36.65037 ? 154 PRO A C   1 
ATOM   1026 O O   . PRO A 1 155 ? 81.33318 41.53610 92.86321  1.000 40.49636 ? 154 PRO A O   1 
ATOM   1027 C CB  . PRO A 1 155 ? 84.29596 41.18103 93.40052  1.000 39.15609 ? 154 PRO A CB  1 
ATOM   1028 C CG  . PRO A 1 155 ? 84.97808 39.84758 93.28367  1.000 36.78878 ? 154 PRO A CG  1 
ATOM   1029 C CD  . PRO A 1 155 ? 83.87841 38.84723 93.31917  1.000 31.28085 ? 154 PRO A CD  1 
ATOM   1030 N N   . ALA A 1 156 ? 81.49300 42.65064 94.81405  1.000 37.32115 ? 155 ALA A N   1 
ATOM   1031 C CA  . ALA A 1 156 ? 80.20860 43.32132 94.65185  1.000 35.34792 ? 155 ALA A CA  1 
ATOM   1032 C C   . ALA A 1 156 ? 80.07708 44.00338 93.30333  1.000 36.06393 ? 155 ALA A C   1 
ATOM   1033 O O   . ALA A 1 156 ? 78.97624 44.05096 92.74477  1.000 38.03364 ? 155 ALA A O   1 
ATOM   1034 C CB  . ALA A 1 156 ? 80.00269 44.34393 95.77107  1.000 35.35518 ? 155 ALA A CB  1 
ATOM   1035 N N   . SER A 1 157 ? 81.17404 44.51713 92.75417  1.000 36.90189 ? 156 SER A N   1 
ATOM   1036 C CA  . SER A 1 157 ? 81.06627 45.41031 91.61093  1.000 36.86445 ? 156 SER A CA  1 
ATOM   1037 C C   . SER A 1 157 ? 82.31552 45.32250 90.74993  1.000 33.18023 ? 156 SER A C   1 
ATOM   1038 O O   . SER A 1 157 ? 83.41825 45.06536 91.23483  1.000 36.23788 ? 156 SER A O   1 
ATOM   1039 C CB  . SER A 1 157 ? 80.82981 46.85448 92.05468  1.000 31.05387 ? 156 SER A CB  1 
ATOM   1040 O OG  . SER A 1 157 ? 81.71923 47.17922 93.09544  1.000 29.52970 ? 156 SER A OG  1 
ATOM   1041 N N   . ALA A 1 158 ? 82.11600 45.51975 89.45769  1.000 31.77994 ? 157 ALA A N   1 
ATOM   1042 C CA  . ALA A 1 158 ? 83.20227 45.52619 88.50373  1.000 35.24144 ? 157 ALA A CA  1 
ATOM   1043 C C   . ALA A 1 158 ? 82.77402 46.40421 87.34540  1.000 42.81006 ? 157 ALA A C   1 
ATOM   1044 O O   . ALA A 1 158 ? 81.57760 46.55795 87.08052  1.000 47.51807 ? 157 ALA A O   1 
ATOM   1045 C CB  . ALA A 1 158 ? 83.52574 44.11237 88.01517  1.000 35.69147 ? 157 ALA A CB  1 
ATOM   1046 N N   . SER A 1 159 ? 83.75454 46.98926 86.66305  1.000 42.96281 ? 158 SER A N   1 
ATOM   1047 C CA  . SER A 1 159 ? 83.44070 47.91226 85.58406  1.000 38.10352 ? 158 SER A CA  1 
ATOM   1048 C C   . SER A 1 159 ? 84.60015 47.95713 84.60513  1.000 37.92051 ? 158 SER A C   1 
ATOM   1049 O O   . SER A 1 159 ? 85.73144 47.58109 84.92166  1.000 32.78767 ? 158 SER A O   1 
ATOM   1050 C CB  . SER A 1 159 ? 83.12719 49.31248 86.11838  1.000 38.49685 ? 158 SER A CB  1 
ATOM   1051 O OG  . SER A 1 159 ? 84.14432 49.75806 86.98864  1.000 38.20653 ? 158 SER A OG  1 
ATOM   1052 N N   . GLY A 1 160 ? 84.30701 48.47629 83.42644  1.000 43.07768 ? 159 GLY A N   1 
ATOM   1053 C CA  . GLY A 1 160 ? 85.31616 48.61298 82.39830  1.000 45.65979 ? 159 GLY A CA  1 
ATOM   1054 C C   . GLY A 1 160 ? 84.80290 49.52548 81.31035  1.000 50.97881 ? 159 GLY A C   1 
ATOM   1055 O O   . GLY A 1 160 ? 83.62946 49.91805 81.29422  1.000 42.59545 ? 159 GLY A O   1 
ATOM   1056 N N   . SER A 1 161 ? 85.72615 49.85017 80.36442  1.000 49.97638 ? 160 SER A N   1 
ATOM   1057 C CA  . SER A 1 161 ? 85.16541 50.64833 79.30119  1.000 45.43010 ? 160 SER A CA  1 
ATOM   1058 C C   . SER A 1 161 ? 84.92424 49.75704 78.09723  1.000 44.54821 ? 160 SER A C   1 
ATOM   1059 O O   . SER A 1 161 ? 85.57698 48.72041 77.95628  1.000 42.92400 ? 160 SER A O   1 
ATOM   1060 C CB  . SER A 1 161 ? 86.11299 51.79493 78.92629  1.000 43.16271 ? 160 SER A CB  1 
ATOM   1061 N N   . PRO A 1 162 ? 83.96658 50.12533 77.24934  1.000 45.41886 ? 161 PRO A N   1 
ATOM   1062 C CA  . PRO A 1 162 ? 83.60916 49.26642 76.11464  1.000 49.50543 ? 161 PRO A CA  1 
ATOM   1063 C C   . PRO A 1 162 ? 84.83489 48.84544 75.32827  1.000 51.72122 ? 161 PRO A C   1 
ATOM   1064 O O   . PRO A 1 162 ? 85.71618 49.65689 75.04047  1.000 51.87989 ? 161 PRO A O   1 
ATOM   1065 C CB  . PRO A 1 162 ? 82.67571 50.14697 75.28243  1.000 45.11116 ? 161 PRO A CB  1 
ATOM   1066 C CG  . PRO A 1 162 ? 82.09310 51.10479 76.24458  1.000 41.05319 ? 161 PRO A CG  1 
ATOM   1067 C CD  . PRO A 1 162 ? 83.02062 51.23864 77.42407  1.000 43.44163 ? 161 PRO A CD  1 
ATOM   1068 N N   . GLY A 1 163 ? 84.91437 47.54734 75.03634  1.000 52.11252 ? 162 GLY A N   1 
ATOM   1069 C CA  . GLY A 1 163 ? 86.05891 46.95835 74.38214  1.000 49.05324 ? 162 GLY A CA  1 
ATOM   1070 C C   . GLY A 1 163 ? 87.12485 46.45103 75.33022  1.000 46.21916 ? 162 GLY A C   1 
ATOM   1071 O O   . GLY A 1 163 ? 87.79209 45.46280 75.02080  1.000 54.62408 ? 162 GLY A O   1 
ATOM   1072 N N   . GLN A 1 164 ? 87.29746 47.09870 76.48026  1.000 48.61194 ? 163 GLN A N   1 
ATOM   1073 C CA  . GLN A 1 164 ? 88.23363 46.60698 77.47875  1.000 46.58508 ? 163 GLN A CA  1 
ATOM   1074 C C   . GLN A 1 164 ? 87.76057 45.25075 78.01281  1.000 47.78247 ? 163 GLN A C   1 
ATOM   1075 O O   . GLN A 1 164 ? 86.64182 44.79530 77.74727  1.000 44.08952 ? 163 GLN A O   1 
ATOM   1076 C CB  . GLN A 1 164 ? 88.39678 47.62436 78.61015  1.000 36.92625 ? 163 GLN A CB  1 
ATOM   1077 N N   . SER A 1 165 ? 88.62683 44.60133 78.77870  1.000 48.52817 ? 164 SER A N   1 
ATOM   1078 C CA  . SER A 1 165 ? 88.28648 43.32265 79.38154  1.000 45.39343 ? 164 SER A CA  1 
ATOM   1079 C C   . SER A 1 165 ? 87.79709 43.52471 80.81498  1.000 47.00943 ? 164 SER A C   1 
ATOM   1080 O O   . SER A 1 165 ? 87.86293 44.63006 81.36477  1.000 43.43252 ? 164 SER A O   1 
ATOM   1081 C CB  . SER A 1 165 ? 89.50909 42.40048 79.34353  1.000 40.56078 ? 164 SER A CB  1 
ATOM   1082 O OG  . SER A 1 165 ? 89.88944 42.16306 78.00518  1.000 54.01866 ? 164 SER A OG  1 
ATOM   1083 N N   . VAL A 1 166 ? 87.24737 42.45039 81.39969  1.000 41.35738 ? 165 VAL A N   1 
ATOM   1084 C CA  . VAL A 1 166 ? 86.77770 42.46005 82.78534  1.000 42.69757 ? 165 VAL A CA  1 
ATOM   1085 C C   . VAL A 1 166 ? 86.90563 41.04509 83.33714  1.000 43.09679 ? 165 VAL A C   1 
ATOM   1086 O O   . VAL A 1 166 ? 86.77484 40.06370 82.59850  1.000 42.99343 ? 165 VAL A O   1 
ATOM   1087 C CB  . VAL A 1 166 ? 85.29706 42.90794 82.91642  1.000 44.70518 ? 165 VAL A CB  1 
ATOM   1088 C CG1 . VAL A 1 166 ? 84.86609 43.00801 84.38389  1.000 49.74262 ? 165 VAL A CG1 1 
ATOM   1089 C CG2 . VAL A 1 166 ? 85.00918 44.17528 82.18867  1.000 50.84813 ? 165 VAL A CG2 1 
ATOM   1090 N N   . THR A 1 167 ? 87.11232 40.92818 84.65134  1.000 38.17584 ? 166 THR A N   1 
ATOM   1091 C CA  . THR A 1 167 ? 87.14960 39.61627 85.28595  1.000 37.80733 ? 166 THR A CA  1 
ATOM   1092 C C   . THR A 1 167 ? 86.32691 39.61869 86.56512  1.000 37.41427 ? 166 THR A C   1 
ATOM   1093 O O   . THR A 1 167 ? 86.43728 40.54645 87.36463  1.000 41.33663 ? 166 THR A O   1 
ATOM   1094 C CB  . THR A 1 167 ? 88.58019 39.18094 85.57965  1.000 37.09242 ? 166 THR A CB  1 
ATOM   1095 O OG1 . THR A 1 167 ? 89.31382 39.11252 84.35308  1.000 39.68999 ? 166 THR A OG1 1 
ATOM   1096 C CG2 . THR A 1 167 ? 88.58533 37.80066 86.20704  1.000 30.93474 ? 166 THR A CG2 1 
ATOM   1097 N N   . ILE A 1 168 ? 85.49140 38.59034 86.74104  1.000 40.03142 ? 167 ILE A N   1 
ATOM   1098 C CA  . ILE A 1 168 ? 84.64173 38.41156 87.91494  1.000 36.33050 ? 167 ILE A CA  1 
ATOM   1099 C C   . ILE A 1 168 ? 85.13411 37.16821 88.64340  1.000 36.12693 ? 167 ILE A C   1 
ATOM   1100 O O   . ILE A 1 168 ? 85.47659 36.16137 88.00909  1.000 37.47999 ? 167 ILE A O   1 
ATOM   1101 C CB  . ILE A 1 168 ? 83.15181 38.25211 87.54243  1.000 36.01568 ? 167 ILE A CB  1 
ATOM   1102 C CG1 . ILE A 1 168 ? 82.61136 39.49845 86.88593  1.000 36.22692 ? 167 ILE A CG1 1 
ATOM   1103 C CG2 . ILE A 1 168 ? 82.34138 38.07931 88.78432  1.000 37.70253 ? 167 ILE A CG2 1 
ATOM   1104 C CD1 . ILE A 1 168 ? 82.88967 40.67315 87.71813  1.000 44.50679 ? 167 ILE A CD1 1 
ATOM   1105 N N   . THR A 1 169 ? 85.20166 37.24342 89.96549  1.000 35.16616 ? 168 THR A N   1 
ATOM   1106 C CA  . THR A 1 169 ? 85.66129 36.13183 90.78393  1.000 33.85762 ? 168 THR A CA  1 
ATOM   1107 C C   . THR A 1 169 ? 84.49027 35.51053 91.52870  1.000 32.86084 ? 168 THR A C   1 
ATOM   1108 O O   . THR A 1 169 ? 83.51139 36.18413 91.84716  1.000 38.08516 ? 168 THR A O   1 
ATOM   1109 C CB  . THR A 1 169 ? 86.72039 36.61064 91.78017  1.000 37.03278 ? 168 THR A CB  1 
ATOM   1110 O OG1 . THR A 1 169 ? 87.81352 37.13612 91.02112  1.000 43.36791 ? 168 THR A OG1 1 
ATOM   1111 C CG2 . THR A 1 169 ? 87.20043 35.46897 92.69019  1.000 38.10756 ? 168 THR A CG2 1 
ATOM   1112 N N   . CYS A 1 170 ? 84.57702 34.21184 91.77227  1.000 33.91583 ? 169 CYS A N   1 
ATOM   1113 C CA  . CYS A 1 170 ? 83.58203 33.48311 92.54822  1.000 33.09394 ? 169 CYS A CA  1 
ATOM   1114 C C   . CYS A 1 170 ? 84.40320 32.50125 93.37133  1.000 38.53805 ? 169 CYS A C   1 
ATOM   1115 O O   . CYS A 1 170 ? 84.88250 31.49180 92.84717  1.000 41.21981 ? 169 CYS A O   1 
ATOM   1116 C CB  . CYS A 1 170 ? 82.56965 32.77581 91.66026  1.000 35.39470 ? 169 CYS A CB  1 
ATOM   1117 S SG  . CYS A 1 170 ? 81.50642 31.64720 92.52518  1.000 43.49426 ? 169 CYS A SG  1 
ATOM   1118 N N   . THR A 1 171 ? 84.60038 32.82358 94.64309  1.000 40.28014 ? 170 THR A N   1 
ATOM   1119 C CA  . THR A 1 171 ? 85.44360 32.03715 95.53158  1.000 45.48608 ? 170 THR A CA  1 
ATOM   1120 C C   . THR A 1 171 ? 84.57263 31.31435 96.55097  1.000 46.94654 ? 170 THR A C   1 
ATOM   1121 O O   . THR A 1 171 ? 83.90149 31.95698 97.36824  1.000 49.18779 ? 170 THR A O   1 
ATOM   1122 C CB  . THR A 1 171 ? 86.47370 32.93421 96.21382  1.000 41.59599 ? 170 THR A CB  1 
ATOM   1123 O OG1 . THR A 1 171 ? 87.42351 33.36349 95.22991  1.000 38.75306 ? 170 THR A OG1 1 
ATOM   1124 C CG2 . THR A 1 171 ? 87.18753 32.18980 97.33806  1.000 35.31666 ? 170 THR A CG2 1 
ATOM   1125 N N   . GLY A 1 172 ? 84.61777 29.98189 96.52253  1.000 40.25192 ? 171 GLY A N   1 
ATOM   1126 C CA  . GLY A 1 172 ? 83.88559 29.15277 97.46391  1.000 43.18865 ? 171 GLY A CA  1 
ATOM   1127 C C   . GLY A 1 172 ? 84.80698 28.27601 98.29092  1.000 47.59282 ? 171 GLY A C   1 
ATOM   1128 O O   . GLY A 1 172 ? 85.79668 28.76318 98.84640  1.000 44.63634 ? 171 GLY A O   1 
ATOM   1129 N N   . SER A 1 173 ? 84.48879 26.98764 98.41934  1.000 41.92782 ? 172 SER A N   1 
ATOM   1130 C CA  . SER A 1 173 ? 85.35741 26.13370 99.21937  1.000 41.66049 ? 172 SER A CA  1 
ATOM   1131 C C   . SER A 1 173 ? 85.68340 24.83608 98.50505  1.000 39.61506 ? 172 SER A C   1 
ATOM   1132 O O   . SER A 1 173 ? 85.40459 24.66467 97.31306  1.000 39.53338 ? 172 SER A O   1 
ATOM   1133 C CB  . SER A 1 173 ? 84.73186 25.81081 100.57519 1.000 39.36834 ? 172 SER A CB  1 
ATOM   1134 O OG  . SER A 1 173 ? 83.92096 24.65386 100.50487 1.000 39.38268 ? 172 SER A OG  1 
ATOM   1135 N N   . SER A 1 174 ? 86.27796 23.91458 99.25093  1.000 42.02446 ? 173 SER A N   1 
ATOM   1136 C CA  . SER A 1 174 ? 86.51680 22.57017 98.73628  1.000 45.50562 ? 173 SER A CA  1 
ATOM   1137 C C   . SER A 1 174 ? 85.21707 21.81825 98.45384  1.000 40.43994 ? 173 SER A C   1 
ATOM   1138 O O   . SER A 1 174 ? 85.16406 20.98977 97.54092  1.000 42.58273 ? 173 SER A O   1 
ATOM   1139 C CB  . SER A 1 174 ? 87.38704 21.80394 99.73273  1.000 46.37289 ? 173 SER A CB  1 
ATOM   1140 O OG  . SER A 1 174 ? 86.73368 21.65980 100.99407 1.000 51.10334 ? 173 SER A OG  1 
ATOM   1141 N N   . SER A 1 175 ? 84.17114 22.07036 99.23124  1.000 39.92402 ? 174 SER A N   1 
ATOM   1142 C CA  . SER A 1 175 ? 82.90306 21.36422 99.08952  1.000 37.79525 ? 174 SER A CA  1 
ATOM   1143 C C   . SER A 1 175 ? 82.04702 21.85202 97.92130  1.000 39.55869 ? 174 SER A C   1 
ATOM   1144 O O   . SER A 1 175 ? 80.93836 21.34509 97.72866  1.000 38.46720 ? 174 SER A O   1 
ATOM   1145 C CB  . SER A 1 175 ? 82.11888 21.47423 100.39102 1.000 39.65787 ? 174 SER A CB  1 
ATOM   1146 O OG  . SER A 1 175 ? 82.90308 21.04728 101.49668 1.000 44.46455 ? 174 SER A OG  1 
ATOM   1147 N N   . ASP A 1 176 ? 82.49196 22.84952 97.17145  1.000 40.41414 ? 175 ASP A N   1 
ATOM   1148 C CA  . ASP A 1 176 ? 81.65704 23.41053 96.11452  1.000 43.94932 ? 175 ASP A CA  1 
ATOM   1149 C C   . ASP A 1 176 ? 82.49715 23.72771 94.87602  1.000 38.78776 ? 175 ASP A C   1 
ATOM   1150 O O   . ASP A 1 176 ? 82.66104 22.86865 94.00128  1.000 31.77881 ? 175 ASP A O   1 
ATOM   1151 C CB  . ASP A 1 176 ? 80.84232 24.59912 96.66128  1.000 34.11508 ? 175 ASP A CB  1 
ATOM   1152 C CG  . ASP A 1 176 ? 81.65565 25.52922 97.51918  1.000 39.91146 ? 175 ASP A CG  1 
ATOM   1153 O OD1 . ASP A 1 176 ? 82.88630 25.63571 97.31911  1.000 38.73224 ? 175 ASP A OD1 1 
ATOM   1154 O OD2 . ASP A 1 176 ? 81.07010 26.07185 98.47845  1.000 40.97512 ? 175 ASP A OD2 1 
ATOM   1155 N N   . VAL A 1 177 ? 82.98438 24.96380 94.76064  1.000 34.00989 ? 176 VAL A N   1 
ATOM   1156 C CA  . VAL A 1 177 ? 83.74112 25.35339 93.57437  1.000 37.17130 ? 176 VAL A CA  1 
ATOM   1157 C C   . VAL A 1 177 ? 84.93291 24.43215 93.35850  1.000 41.28415 ? 176 VAL A C   1 
ATOM   1158 O O   . VAL A 1 177 ? 85.16987 23.94757 92.24303  1.000 41.20214 ? 176 VAL A O   1 
ATOM   1159 C CB  . VAL A 1 177 ? 84.19812 26.81491 93.68558  1.000 33.31571 ? 176 VAL A CB  1 
ATOM   1160 C CG1 . VAL A 1 177 ? 84.93427 27.20810 92.43520  1.000 31.34322 ? 176 VAL A CG1 1 
ATOM   1161 C CG2 . VAL A 1 177 ? 83.00537 27.70073 93.90603  1.000 34.30957 ? 176 VAL A CG2 1 
ATOM   1162 N N   . GLY A 1 178 ? 85.69364 24.16728 94.41806  1.000 35.53050 ? 177 GLY A N   1 
ATOM   1163 C CA  . GLY A 1 178 ? 86.88925 23.37363 94.24521  1.000 37.47651 ? 177 GLY A CA  1 
ATOM   1164 C C   . GLY A 1 178 ? 86.74544 21.87274 94.31741  1.000 37.05538 ? 177 GLY A C   1 
ATOM   1165 O O   . GLY A 1 178 ? 87.74392 21.16258 94.16760  1.000 36.32628 ? 177 GLY A O   1 
ATOM   1166 N N   . GLY A 1 179 ? 85.53676 21.35479 94.48059  1.000 33.28404 ? 178 GLY A N   1 
ATOM   1167 C CA  . GLY A 1 179 ? 85.35707 19.92478 94.61661  1.000 37.19808 ? 178 GLY A CA  1 
ATOM   1168 C C   . GLY A 1 179 ? 84.76709 19.31526 93.36341  1.000 40.84964 ? 178 GLY A C   1 
ATOM   1169 O O   . GLY A 1 179 ? 84.66990 18.08866 93.21690  1.000 32.93324 ? 178 GLY A O   1 
ATOM   1170 N N   . TYR A 1 180 ? 84.31866 20.19042 92.46569  1.000 41.17507 ? 179 TYR A N   1 
ATOM   1171 C CA  . TYR A 1 180 ? 83.55493 19.76896 91.30580  1.000 41.56886 ? 179 TYR A CA  1 
ATOM   1172 C C   . TYR A 1 180 ? 83.93531 20.56917 90.06934  1.000 41.27398 ? 179 TYR A C   1 
ATOM   1173 O O   . TYR A 1 180 ? 84.70178 21.54008 90.12128  1.000 39.91647 ? 179 TYR A O   1 
ATOM   1174 C CB  . TYR A 1 180 ? 82.05774 19.91278 91.56472  1.000 35.74872 ? 179 TYR A CB  1 
ATOM   1175 C CG  . TYR A 1 180 ? 81.61435 19.13226 92.75820  1.000 35.34024 ? 179 TYR A CG  1 
ATOM   1176 C CD1 . TYR A 1 180 ? 80.97853 17.91477 92.61736  1.000 37.02420 ? 179 TYR A CD1 1 
ATOM   1177 C CD2 . TYR A 1 180 ? 81.86044 19.59822 94.03444  1.000 36.94707 ? 179 TYR A CD2 1 
ATOM   1178 C CE1 . TYR A 1 180 ? 80.58954 17.19527 93.72299  1.000 36.10588 ? 179 TYR A CE1 1 
ATOM   1179 C CE2 . TYR A 1 180 ? 81.49578 18.88124 95.13525  1.000 37.98441 ? 179 TYR A CE2 1 
ATOM   1180 C CZ  . TYR A 1 180 ? 80.85392 17.68717 94.97800  1.000 36.21020 ? 179 TYR A CZ  1 
ATOM   1181 O OH  . TYR A 1 180 ? 80.46445 16.99341 96.08600  1.000 38.08644 ? 179 TYR A OH  1 
ATOM   1182 N N   . LYS A 1 181 ? 83.40084 20.10987 88.93900  1.000 37.49166 ? 180 LYS A N   1 
ATOM   1183 C CA  . LYS A 1 181 ? 83.52876 20.78050 87.65380  1.000 37.24148 ? 180 LYS A CA  1 
ATOM   1184 C C   . LYS A 1 181 ? 82.15872 21.29574 87.24692  1.000 38.00372 ? 180 LYS A C   1 
ATOM   1185 O O   . LYS A 1 181 ? 81.78896 21.28363 86.07490  1.000 41.63345 ? 180 LYS A O   1 
ATOM   1186 C CB  . LYS A 1 181 ? 84.08622 19.84135 86.58291  1.000 41.70359 ? 180 LYS A CB  1 
ATOM   1187 C CG  . LYS A 1 181 ? 85.57556 19.51701 86.73926  1.000 47.46383 ? 180 LYS A CG  1 
ATOM   1188 C CD  . LYS A 1 181 ? 85.71832 18.53528 87.92349  1.000 58.34147 ? 180 LYS A CD  1 
ATOM   1189 C CE  . LYS A 1 181 ? 87.12234 18.07094 88.28166  1.000 60.20660 ? 180 LYS A CE  1 
ATOM   1190 N NZ  . LYS A 1 181 ? 87.02380 17.29858 89.57365  1.000 50.38994 ? 180 LYS A NZ  1 
ATOM   1191 N N   . TYR A 1 182 ? 81.39954 21.77566 88.22370  1.000 36.28234 ? 181 TYR A N   1 
ATOM   1192 C CA  . TYR A 1 182 ? 80.06914 22.31816 87.98659  1.000 36.68293 ? 181 TYR A CA  1 
ATOM   1193 C C   . TYR A 1 182 ? 79.97646 23.72118 88.58103  1.000 34.53176 ? 181 TYR A C   1 
ATOM   1194 O O   . TYR A 1 182 ? 79.36020 23.93937 89.62494  1.000 35.93666 ? 181 TYR A O   1 
ATOM   1195 C CB  . TYR A 1 182 ? 79.02521 21.37817 88.56050  1.000 32.56073 ? 181 TYR A CB  1 
ATOM   1196 C CG  . TYR A 1 182 ? 79.08461 20.01113 87.93408  1.000 38.79682 ? 181 TYR A CG  1 
ATOM   1197 C CD1 . TYR A 1 182 ? 79.15352 19.86309 86.54927  1.000 40.77566 ? 181 TYR A CD1 1 
ATOM   1198 C CD2 . TYR A 1 182 ? 79.07495 18.86071 88.72214  1.000 42.64089 ? 181 TYR A CD2 1 
ATOM   1199 C CE1 . TYR A 1 182 ? 79.21315 18.61180 85.97215  1.000 43.66247 ? 181 TYR A CE1 1 
ATOM   1200 C CE2 . TYR A 1 182 ? 79.12785 17.60357 88.15379  1.000 34.04887 ? 181 TYR A CE2 1 
ATOM   1201 C CZ  . TYR A 1 182 ? 79.20014 17.48423 86.78761  1.000 42.95437 ? 181 TYR A CZ  1 
ATOM   1202 O OH  . TYR A 1 182 ? 79.26212 16.22787 86.23895  1.000 50.11408 ? 181 TYR A OH  1 
ATOM   1203 N N   . VAL A 1 183 ? 80.57029 24.68763 87.89990  1.000 29.39559 ? 182 VAL A N   1 
ATOM   1204 C CA  . VAL A 1 183 ? 80.37961 26.08518 88.24150  1.000 28.53090 ? 182 VAL A CA  1 
ATOM   1205 C C   . VAL A 1 183 ? 79.64234 26.73840 87.08053  1.000 34.98070 ? 182 VAL A C   1 
ATOM   1206 O O   . VAL A 1 183 ? 80.10336 26.67501 85.93388  1.000 35.95343 ? 182 VAL A O   1 
ATOM   1207 C CB  . VAL A 1 183 ? 81.71095 26.79346 88.52503  1.000 33.97659 ? 182 VAL A CB  1 
ATOM   1208 C CG1 . VAL A 1 183 ? 81.44599 28.16268 89.11532  1.000 34.80205 ? 182 VAL A CG1 1 
ATOM   1209 C CG2 . VAL A 1 183 ? 82.57217 25.96914 89.47132  1.000 33.41871 ? 182 VAL A CG2 1 
ATOM   1210 N N   . SER A 1 184 ? 78.50047 27.36431 87.37247  1.000 32.10371 ? 183 SER A N   1 
ATOM   1211 C CA  . SER A 1 184 ? 77.74615 28.13064 86.39237  1.000 28.05062 ? 183 SER A CA  1 
ATOM   1212 C C   . SER A 1 184 ? 77.83441 29.61398 86.73239  1.000 30.31181 ? 183 SER A C   1 
ATOM   1213 O O   . SER A 1 184 ? 78.06541 29.99256 87.88395  1.000 31.59101 ? 183 SER A O   1 
ATOM   1214 C CB  . SER A 1 184 ? 76.26966 27.71304 86.36897  1.000 24.44139 ? 183 SER A CB  1 
ATOM   1215 O OG  . SER A 1 184 ? 76.11447 26.33408 86.12156  1.000 28.51231 ? 183 SER A OG  1 
ATOM   1216 N N   . TRP A 1 185 ? 77.61913 30.45738 85.71932  1.000 29.48144 ? 184 TRP A N   1 
ATOM   1217 C CA  . TRP A 1 185 ? 77.44347 31.89876 85.90213  1.000 30.18078 ? 184 TRP A CA  1 
ATOM   1218 C C   . TRP A 1 185 ? 76.18085 32.31955 85.17369  1.000 25.85821 ? 184 TRP A C   1 
ATOM   1219 O O   . TRP A 1 185 ? 76.01197 32.00252 83.99656  1.000 29.04040 ? 184 TRP A O   1 
ATOM   1220 C CB  . TRP A 1 185 ? 78.59550 32.73722 85.34717  1.000 27.42288 ? 184 TRP A CB  1 
ATOM   1221 C CG  . TRP A 1 185 ? 79.94261 32.47641 85.89428  1.000 31.94190 ? 184 TRP A CG  1 
ATOM   1222 C CD1 . TRP A 1 185 ? 80.79691 31.48279 85.52869  1.000 29.44029 ? 184 TRP A CD1 1 
ATOM   1223 C CD2 . TRP A 1 185 ? 80.62428 33.25173 86.88393  1.000 33.44729 ? 184 TRP A CD2 1 
ATOM   1224 N NE1 . TRP A 1 185 ? 81.96820 31.58807 86.23336  1.000 30.60564 ? 184 TRP A NE1 1 
ATOM   1225 C CE2 . TRP A 1 185 ? 81.88439 32.66367 87.07790  1.000 32.32046 ? 184 TRP A CE2 1 
ATOM   1226 C CE3 . TRP A 1 185 ? 80.28606 34.38341 87.63067  1.000 34.79358 ? 184 TRP A CE3 1 
ATOM   1227 C CZ2 . TRP A 1 185 ? 82.80874 33.16784 87.98854  1.000 32.79299 ? 184 TRP A CZ2 1 
ATOM   1228 C CZ3 . TRP A 1 185 ? 81.19289 34.87107 88.53283  1.000 30.15359 ? 184 TRP A CZ3 1 
ATOM   1229 C CH2 . TRP A 1 185 ? 82.44617 34.27596 88.69683  1.000 32.84100 ? 184 TRP A CH2 1 
ATOM   1230 N N   . TYR A 1 186 ? 75.31908 33.05334 85.84779  1.000 21.96693 ? 185 TYR A N   1 
ATOM   1231 C CA  . TYR A 1 186 ? 74.11338 33.56971 85.22944  1.000 23.25720 ? 185 TYR A CA  1 
ATOM   1232 C C   . TYR A 1 186 ? 74.23210 35.08187 85.05335  1.000 29.41111 ? 185 TYR A C   1 
ATOM   1233 O O   . TYR A 1 186 ? 74.97091 35.76146 85.77642  1.000 25.20642 ? 185 TYR A O   1 
ATOM   1234 C CB  . TYR A 1 186 ? 72.87237 33.21149 86.05635  1.000 25.76327 ? 185 TYR A CB  1 
ATOM   1235 C CG  . TYR A 1 186 ? 72.65728 31.72684 86.21975  1.000 27.71490 ? 185 TYR A CG  1 
ATOM   1236 C CD1 . TYR A 1 186 ? 73.39842 30.99485 87.13964  1.000 22.58602 ? 185 TYR A CD1 1 
ATOM   1237 C CD2 . TYR A 1 186 ? 71.71603 31.05643 85.44809  1.000 30.83223 ? 185 TYR A CD2 1 
ATOM   1238 C CE1 . TYR A 1 186 ? 73.21250 29.63785 87.28913  1.000 27.54367 ? 185 TYR A CE1 1 
ATOM   1239 C CE2 . TYR A 1 186 ? 71.51476 29.69232 85.58739  1.000 28.02161 ? 185 TYR A CE2 1 
ATOM   1240 C CZ  . TYR A 1 186 ? 72.26768 28.98450 86.50747  1.000 34.13748 ? 185 TYR A CZ  1 
ATOM   1241 O OH  . TYR A 1 186 ? 72.07785 27.61931 86.64696  1.000 32.93953 ? 185 TYR A OH  1 
ATOM   1242 N N   . GLN A 1 187 ? 73.57271 35.60048 84.02854  1.000 27.50898 ? 186 GLN A N   1 
ATOM   1243 C CA  . GLN A 1 187 ? 73.46550 37.03622 83.84650  1.000 25.64905 ? 186 GLN A CA  1 
ATOM   1244 C C   . GLN A 1 187 ? 72.02059 37.42500 84.09930  1.000 29.44635 ? 186 GLN A C   1 
ATOM   1245 O O   . GLN A 1 187 ? 71.10507 36.74998 83.61631  1.000 31.31589 ? 186 GLN A O   1 
ATOM   1246 C CB  . GLN A 1 187 ? 73.93112 37.44166 82.46136  1.000 29.48197 ? 186 GLN A CB  1 
ATOM   1247 C CG  . GLN A 1 187 ? 73.56226 38.83075 82.06097  1.000 29.51437 ? 186 GLN A CG  1 
ATOM   1248 C CD  . GLN A 1 187 ? 73.99371 39.10180 80.64573  1.000 27.75849 ? 186 GLN A CD  1 
ATOM   1249 O OE1 . GLN A 1 187 ? 74.96187 39.81861 80.40236  1.000 31.25621 ? 186 GLN A OE1 1 
ATOM   1250 N NE2 . GLN A 1 187 ? 73.30433 38.49045 79.70205  1.000 21.14278 ? 186 GLN A NE2 1 
ATOM   1251 N N   . HIS A 1 188 ? 71.81957 38.48013 84.89330  1.000 31.24497 ? 187 HIS A N   1 
ATOM   1252 C CA  . HIS A 1 188 ? 70.49339 38.85639 85.37084  1.000 27.45622 ? 187 HIS A CA  1 
ATOM   1253 C C   . HIS A 1 188 ? 70.19710 40.31437 85.07511  1.000 37.87303 ? 187 HIS A C   1 
ATOM   1254 O O   . HIS A 1 188 ? 70.85577 41.22032 85.60414  1.000 32.68420 ? 187 HIS A O   1 
ATOM   1255 C CB  . HIS A 1 188 ? 70.35841 38.61023 86.86990  1.000 25.19701 ? 187 HIS A CB  1 
ATOM   1256 C CG  . HIS A 1 188 ? 69.09823 39.15746 87.45005  1.000 32.38825 ? 187 HIS A CG  1 
ATOM   1257 N ND1 . HIS A 1 188 ? 67.85406 38.68048 87.09979  1.000 37.67404 ? 187 HIS A ND1 1 
ATOM   1258 C CD2 . HIS A 1 188 ? 68.88245 40.14842 88.35161  1.000 40.01809 ? 187 HIS A CD2 1 
ATOM   1259 C CE1 . HIS A 1 188 ? 66.92535 39.34540 87.76932  1.000 39.30587 ? 187 HIS A CE1 1 
ATOM   1260 N NE2 . HIS A 1 188 ? 67.52236 40.24422 88.53313  1.000 38.74275 ? 187 HIS A NE2 1 
ATOM   1261 N N   . HIS A 1 189 ? 69.19963 40.52379 84.30900  1.000 41.83600 ? 188 HIS A N   1 
ATOM   1262 C CA  . HIS A 1 189 ? 68.64490 41.83369 84.09224  1.000 33.26755 ? 188 HIS A CA  1 
ATOM   1263 C C   . HIS A 1 189 ? 67.35136 41.96515 84.86986  1.000 35.14423 ? 188 HIS A C   1 
ATOM   1264 O O   . HIS A 1 189 ? 66.48274 41.07866 84.76966  1.000 28.62760 ? 188 HIS A O   1 
ATOM   1265 C CB  . HIS A 1 189 ? 68.39845 42.04657 82.60943  1.000 33.56100 ? 188 HIS A CB  1 
ATOM   1266 C CG  . HIS A 1 189 ? 69.63656 42.38090 81.83953  1.000 39.94680 ? 188 HIS A CG  1 
ATOM   1267 N ND1 . HIS A 1 189 ? 69.87019 41.91465 80.56307  1.000 47.05702 ? 188 HIS A ND1 1 
ATOM   1268 C CD2 . HIS A 1 189 ? 70.69313 43.16880 82.14957  1.000 42.01883 ? 188 HIS A CD2 1 
ATOM   1269 C CE1 . HIS A 1 189 ? 71.02892 42.37989 80.12899  1.000 42.38800 ? 188 HIS A CE1 1 
ATOM   1270 N NE2 . HIS A 1 189 ? 71.54594 43.14770 81.07129  1.000 44.36194 ? 188 HIS A NE2 1 
ATOM   1271 N N   . PRO A 1 190 ? 67.20447 43.06424 85.64631  1.000 40.73194 ? 189 PRO A N   1 
ATOM   1272 C CA  . PRO A 1 190 ? 66.01445 43.24445 86.48894  1.000 32.13334 ? 189 PRO A CA  1 
ATOM   1273 C C   . PRO A 1 190 ? 64.71649 43.07492 85.73329  1.000 33.17643 ? 189 PRO A C   1 
ATOM   1274 O O   . PRO A 1 190 ? 64.43334 43.83061 84.80543  1.000 40.18242 ? 189 PRO A O   1 
ATOM   1275 C CB  . PRO A 1 190 ? 66.15909 44.68258 86.98333  1.000 30.72178 ? 189 PRO A CB  1 
ATOM   1276 C CG  . PRO A 1 190 ? 67.61148 44.96896 86.90349  1.000 32.24386 ? 189 PRO A CG  1 
ATOM   1277 C CD  . PRO A 1 190 ? 68.12565 44.21088 85.73446  1.000 36.67488 ? 189 PRO A CD  1 
ATOM   1278 N N   . GLY A 1 191 ? 63.90754 42.10851 86.14751  1.000 37.56066 ? 190 GLY A N   1 
ATOM   1279 C CA  . GLY A 1 191 ? 62.64352 41.83584 85.50965  1.000 34.68420 ? 190 GLY A CA  1 
ATOM   1280 C C   . GLY A 1 191 ? 62.70243 40.76547 84.45193  1.000 42.55067 ? 190 GLY A C   1 
ATOM   1281 O O   . GLY A 1 191 ? 61.64273 40.30686 83.99021  1.000 45.24265 ? 190 GLY A O   1 
ATOM   1282 N N   . LYS A 1 192 ? 63.89306 40.26545 84.14397  1.000 44.36942 ? 191 LYS A N   1 
ATOM   1283 C CA  . LYS A 1 192 ? 64.07832 39.30047 83.07585  1.000 46.41170 ? 191 LYS A CA  1 
ATOM   1284 C C   . LYS A 1 192 ? 64.57015 37.96099 83.63425  1.000 37.10889 ? 191 LYS A C   1 
ATOM   1285 O O   . LYS A 1 192 ? 65.04030 37.86021 84.76868  1.000 42.12131 ? 191 LYS A O   1 
ATOM   1286 C CB  . LYS A 1 192 ? 65.05346 39.87524 82.03548  1.000 36.81894 ? 191 LYS A CB  1 
ATOM   1287 N N   . ALA A 1 193 ? 64.43781 36.92662 82.84290  1.000 31.29147 ? 192 ALA A N   1 
ATOM   1288 C CA  . ALA A 1 193 ? 64.84300 35.60659 83.30107  1.000 37.81607 ? 192 ALA A CA  1 
ATOM   1289 C C   . ALA A 1 193 ? 66.35990 35.50419 83.35785  1.000 31.87083 ? 192 ALA A C   1 
ATOM   1290 O O   . ALA A 1 193 ? 67.03036 35.84277 82.38068  1.000 33.09478 ? 192 ALA A O   1 
ATOM   1291 C CB  . ALA A 1 193 ? 64.30728 34.53964 82.35329  1.000 39.05617 ? 192 ALA A CB  1 
ATOM   1292 N N   . PRO A 1 194 ? 66.93441 35.02609 84.45599  1.000 28.41141 ? 193 PRO A N   1 
ATOM   1293 C CA  . PRO A 1 194 ? 68.38455 34.83656 84.48463  1.000 27.71129 ? 193 PRO A CA  1 
ATOM   1294 C C   . PRO A 1 194 ? 68.76644 33.88765 83.36188  1.000 35.70383 ? 193 PRO A C   1 
ATOM   1295 O O   . PRO A 1 194 ? 67.96665 33.05235 82.92163  1.000 33.86350 ? 193 PRO A O   1 
ATOM   1296 C CB  . PRO A 1 194 ? 68.64557 34.22186 85.86557  1.000 31.61602 ? 193 PRO A CB  1 
ATOM   1297 C CG  . PRO A 1 194 ? 67.35764 34.37129 86.62807  1.000 28.96178 ? 193 PRO A CG  1 
ATOM   1298 C CD  . PRO A 1 194 ? 66.26493 34.44735 85.62798  1.000 29.41187 ? 193 PRO A CD  1 
ATOM   1299 N N   . LYS A 1 195 ? 69.97557 34.06060 82.84894  1.000 32.62632 ? 194 LYS A N   1 
ATOM   1300 C CA  . LYS A 1 195 ? 70.38100 33.35827 81.64179  1.000 27.84155 ? 194 LYS A CA  1 
ATOM   1301 C C   . LYS A 1 195 ? 71.74544 32.70053 81.80714  1.000 32.94301 ? 194 LYS A C   1 
ATOM   1302 O O   . LYS A 1 195 ? 72.69474 33.36601 82.23254  1.000 36.16148 ? 194 LYS A O   1 
ATOM   1303 C CB  . LYS A 1 195 ? 70.39053 34.33400 80.46633  1.000 30.84685 ? 194 LYS A CB  1 
ATOM   1304 C CG  . LYS A 1 195 ? 70.75115 33.66491 79.18655  1.000 47.47612 ? 194 LYS A CG  1 
ATOM   1305 C CD  . LYS A 1 195 ? 71.30008 34.59460 78.14326  1.000 38.55485 ? 194 LYS A CD  1 
ATOM   1306 C CE  . LYS A 1 195 ? 71.38956 33.83227 76.83818  1.000 46.56024 ? 194 LYS A CE  1 
ATOM   1307 N NZ  . LYS A 1 195 ? 71.94723 34.62185 75.72626  1.000 53.29038 ? 194 LYS A NZ  1 
ATOM   1308 N N   . LEU A 1 196 ? 71.86432 31.40971 81.45482  1.000 31.18406 ? 195 LEU A N   1 
ATOM   1309 C CA  . LEU A 1 196 ? 73.18742 30.77437 81.46424  1.000 30.03906 ? 195 LEU A CA  1 
ATOM   1310 C C   . LEU A 1 196 ? 74.14466 31.36413 80.45619  1.000 36.85351 ? 195 LEU A C   1 
ATOM   1311 O O   . LEU A 1 196 ? 73.87518 31.40757 79.24786  1.000 37.85508 ? 195 LEU A O   1 
ATOM   1312 C CB  . LEU A 1 196 ? 73.18453 29.26339 81.26101  1.000 29.94561 ? 195 LEU A CB  1 
ATOM   1313 C CG  . LEU A 1 196 ? 73.09841 28.38088 82.48327  1.000 32.78166 ? 195 LEU A CG  1 
ATOM   1314 C CD1 . LEU A 1 196 ? 73.00643 26.95031 82.07243  1.000 40.16678 ? 195 LEU A CD1 1 
ATOM   1315 C CD2 . LEU A 1 196 ? 74.44461 28.59225 83.14695  1.000 30.60200 ? 195 LEU A CD2 1 
ATOM   1316 N N   . MET A 1 197 ? 75.26627 31.82643 80.99436  1.000 31.23254 ? 196 MET A N   1 
ATOM   1317 C CA  . MET A 1 197 ? 76.42271 32.28238 80.25280  1.000 30.89458 ? 196 MET A CA  1 
ATOM   1318 C C   . MET A 1 197 ? 77.49052 31.21450 80.20065  1.000 26.78966 ? 196 MET A C   1 
ATOM   1319 O O   . MET A 1 197 ? 78.11000 31.00341 79.16182  1.000 29.97808 ? 196 MET A O   1 
ATOM   1320 C CB  . MET A 1 197 ? 77.01755 33.52567 80.92214  1.000 32.30294 ? 196 MET A CB  1 
ATOM   1321 C CG  . MET A 1 197 ? 76.12656 34.71285 80.92434  1.000 31.36318 ? 196 MET A CG  1 
ATOM   1322 S SD  . MET A 1 197 ? 75.87951 35.16179 79.21256  1.000 39.74462 ? 196 MET A SD  1 
ATOM   1323 C CE  . MET A 1 197 ? 74.15584 35.54886 79.29769  1.000 27.64021 ? 196 MET A CE  1 
ATOM   1324 N N   . ILE A 1 198 ? 77.72399 30.55440 81.32190  1.000 25.52254 ? 197 ILE A N   1 
ATOM   1325 C CA  . ILE A 1 198 ? 78.78560 29.57142 81.43793  1.000 26.54105 ? 197 ILE A CA  1 
ATOM   1326 C C   . ILE A 1 198 ? 78.28812 28.41744 82.29216  1.000 28.84898 ? 197 ILE A C   1 
ATOM   1327 O O   . ILE A 1 198 ? 77.62894 28.61372 83.31904  1.000 26.45595 ? 197 ILE A O   1 
ATOM   1328 C CB  . ILE A 1 198 ? 80.06101 30.19938 82.03767  1.000 24.74303 ? 197 ILE A CB  1 
ATOM   1329 C CG1 . ILE A 1 198 ? 80.72167 31.17892 81.06098  1.000 26.67745 ? 197 ILE A CG1 1 
ATOM   1330 C CG2 . ILE A 1 198 ? 81.03156 29.13778 82.43778  1.000 25.03731 ? 197 ILE A CG2 1 
ATOM   1331 C CD1 . ILE A 1 198 ? 81.45816 30.52957 79.93780  1.000 32.86881 ? 197 ILE A CD1 1 
ATOM   1332 N N   . TYR A 1 199 ? 78.62828 27.20674 81.88161  1.000 38.17505 ? 198 TYR A N   1 
ATOM   1333 C CA  . TYR A 1 199 ? 78.30886 26.04056 82.67974  1.000 34.67989 ? 198 TYR A CA  1 
ATOM   1334 C C   . TYR A 1 199 ? 79.49373 25.09545 82.65015  1.000 32.01240 ? 198 TYR A C   1 
ATOM   1335 O O   . TYR A 1 199 ? 80.37584 25.19977 81.79495  1.000 28.11582 ? 198 TYR A O   1 
ATOM   1336 C CB  . TYR A 1 199 ? 77.02857 25.36797 82.18739  1.000 34.43672 ? 198 TYR A CB  1 
ATOM   1337 C CG  . TYR A 1 199 ? 77.12958 24.56646 80.90613  1.000 37.25767 ? 198 TYR A CG  1 
ATOM   1338 C CD1 . TYR A 1 199 ? 77.51166 23.22739 80.93770  1.000 39.06868 ? 198 TYR A CD1 1 
ATOM   1339 C CD2 . TYR A 1 199 ? 76.78761 25.12216 79.67310  1.000 32.31424 ? 198 TYR A CD2 1 
ATOM   1340 C CE1 . TYR A 1 199 ? 77.58124 22.47703 79.78731  1.000 35.00448 ? 198 TYR A CE1 1 
ATOM   1341 C CE2 . TYR A 1 199 ? 76.85068 24.36251 78.51057  1.000 33.46794 ? 198 TYR A CE2 1 
ATOM   1342 C CZ  . TYR A 1 199 ? 77.25237 23.04220 78.58457  1.000 32.24245 ? 198 TYR A CZ  1 
ATOM   1343 O OH  . TYR A 1 199 ? 77.33606 22.24759 77.47409  1.000 34.51163 ? 198 TYR A OH  1 
ATOM   1344 N N   . GLU A 1 200 ? 79.50232 24.17455 83.60588  1.000 35.83867 ? 199 GLU A N   1 
ATOM   1345 C CA  . GLU A 1 200 ? 80.61652 23.25156 83.78080  1.000 36.96316 ? 199 GLU A CA  1 
ATOM   1346 C C   . GLU A 1 200 ? 81.93500 24.01166 83.72191  1.000 36.31000 ? 199 GLU A C   1 
ATOM   1347 O O   . GLU A 1 200 ? 82.85727 23.66631 82.98608  1.000 37.09899 ? 199 GLU A O   1 
ATOM   1348 C CB  . GLU A 1 200 ? 80.56441 22.12573 82.74979  1.000 30.80953 ? 199 GLU A CB  1 
ATOM   1349 C CG  . GLU A 1 200 ? 79.61551 21.01570 83.17245  1.000 41.70004 ? 199 GLU A CG  1 
ATOM   1350 C CD  . GLU A 1 200 ? 79.19117 20.11247 82.03206  1.000 37.61904 ? 199 GLU A CD  1 
ATOM   1351 O OE1 . GLU A 1 200 ? 80.01434 19.87587 81.11666  1.000 37.33131 ? 199 GLU A OE1 1 
ATOM   1352 O OE2 . GLU A 1 200 ? 78.02524 19.64966 82.05934  1.000 32.69192 ? 199 GLU A OE2 1 
ATOM   1353 N N   . VAL A 1 201 ? 81.98584 25.09137 84.49424  1.000 38.20156 ? 200 VAL A N   1 
ATOM   1354 C CA  . VAL A 1 201 ? 83.16939 25.92205 84.66948  1.000 38.04178 ? 200 VAL A CA  1 
ATOM   1355 C C   . VAL A 1 201 ? 83.44599 26.77697 83.43678  1.000 38.92812 ? 200 VAL A C   1 
ATOM   1356 O O   . VAL A 1 201 ? 83.61903 27.99574 83.55965  1.000 42.22073 ? 200 VAL A O   1 
ATOM   1357 C CB  . VAL A 1 201 ? 84.39173 25.07718 85.06130  1.000 33.86162 ? 200 VAL A CB  1 
ATOM   1358 C CG1 . VAL A 1 201 ? 85.63672 25.93617 85.07794  1.000 35.87187 ? 200 VAL A CG1 1 
ATOM   1359 C CG2 . VAL A 1 201 ? 84.15696 24.47695 86.42089  1.000 36.01496 ? 200 VAL A CG2 1 
ATOM   1360 N N   . SER A 1 202 ? 83.48873 26.17473 82.23950  1.000 34.97157 ? 201 SER A N   1 
ATOM   1361 C CA  . SER A 1 202 ? 83.97147 26.93782 81.09330  1.000 32.04536 ? 201 SER A CA  1 
ATOM   1362 C C   . SER A 1 202 ? 83.18618 26.78938 79.78987  1.000 33.57092 ? 201 SER A C   1 
ATOM   1363 O O   . SER A 1 202 ? 83.64631 27.29682 78.76182  1.000 45.56479 ? 201 SER A O   1 
ATOM   1364 C CB  . SER A 1 202 ? 85.42167 26.56686 80.83511  1.000 31.68893 ? 201 SER A CB  1 
ATOM   1365 O OG  . SER A 1 202 ? 85.46703 25.26011 80.28458  1.000 41.22566 ? 201 SER A OG  1 
ATOM   1366 N N   . LYS A 1 203 ? 82.04524 26.11158 79.76758  1.000 33.39742 ? 202 LYS A N   1 
ATOM   1367 C CA  . LYS A 1 203 ? 81.33960 25.87117 78.51208  1.000 31.98083 ? 202 LYS A CA  1 
ATOM   1368 C C   . LYS A 1 203 ? 80.32795 26.97055 78.23203  1.000 32.43023 ? 202 LYS A C   1 
ATOM   1369 O O   . LYS A 1 203 ? 79.59246 27.39353 79.12555  1.000 33.88218 ? 202 LYS A O   1 
ATOM   1370 C CB  . LYS A 1 203 ? 80.65368 24.50282 78.54490  1.000 27.09504 ? 202 LYS A CB  1 
ATOM   1371 C CG  . LYS A 1 203 ? 81.67899 23.40362 78.79535  1.000 30.88184 ? 202 LYS A CG  1 
ATOM   1372 C CD  . LYS A 1 203 ? 81.14084 21.98202 78.69992  1.000 34.80624 ? 202 LYS A CD  1 
ATOM   1373 C CE  . LYS A 1 203 ? 82.28455 20.97195 78.63094  1.000 31.56707 ? 202 LYS A CE  1 
ATOM   1374 N NZ  . LYS A 1 203 ? 83.29106 21.10277 79.73662  1.000 36.97404 ? 202 LYS A NZ  1 
ATOM   1375 N N   . ARG A 1 204 ? 80.25388 27.38929 76.96824  1.000 35.33184 ? 203 ARG A N   1 
ATOM   1376 C CA  . ARG A 1 204 ? 79.28291 28.39525 76.55200  1.000 28.96203 ? 203 ARG A CA  1 
ATOM   1377 C C   . ARG A 1 204 ? 78.07870 27.69795 75.95531  1.000 29.99622 ? 203 ARG A C   1 
ATOM   1378 O O   . ARG A 1 204 ? 78.24476 26.94448 74.98306  1.000 31.95446 ? 203 ARG A O   1 
ATOM   1379 C CB  . ARG A 1 204 ? 79.89080 29.33119 75.51193  1.000 35.32356 ? 203 ARG A CB  1 
ATOM   1380 C CG  . ARG A 1 204 ? 80.47128 30.60904 76.03782  1.000 41.87517 ? 203 ARG A CG  1 
ATOM   1381 C CD  . ARG A 1 204 ? 81.89332 30.52168 76.55232  1.000 43.17237 ? 203 ARG A CD  1 
ATOM   1382 N NE  . ARG A 1 204 ? 82.95093 30.36750 75.55576  1.000 42.34719 ? 203 ARG A NE  1 
ATOM   1383 C CZ  . ARG A 1 204 ? 84.24272 30.29367 75.88438  1.000 49.23325 ? 203 ARG A CZ  1 
ATOM   1384 N NH1 . ARG A 1 204 ? 85.18102 30.15379 74.95445  1.000 47.59122 ? 203 ARG A NH1 1 
ATOM   1385 N NH2 . ARG A 1 204 ? 84.60191 30.40734 77.16047  1.000 49.62311 ? 203 ARG A NH2 1 
ATOM   1386 N N   . PRO A 1 205 ? 76.86585 27.92207 76.46760  1.000 32.00823 ? 204 PRO A N   1 
ATOM   1387 C CA  . PRO A 1 205 ? 75.68234 27.32891 75.84532  1.000 30.23213 ? 204 PRO A CA  1 
ATOM   1388 C C   . PRO A 1 205 ? 75.52202 27.85238 74.43188  1.000 36.86405 ? 204 PRO A C   1 
ATOM   1389 O O   . PRO A 1 205 ? 76.18697 28.80396 74.01777  1.000 41.59376 ? 204 PRO A O   1 
ATOM   1390 C CB  . PRO A 1 205 ? 74.52999 27.78853 76.74361  1.000 29.04062 ? 204 PRO A CB  1 
ATOM   1391 C CG  . PRO A 1 205 ? 75.14060 28.16664 78.00702  1.000 25.82551 ? 204 PRO A CG  1 
ATOM   1392 C CD  . PRO A 1 205 ? 76.52501 28.63463 77.70896  1.000 34.65444 ? 204 PRO A CD  1 
ATOM   1393 N N   . SER A 1 206 ? 74.61557 27.23213 73.68140  1.000 38.27486 ? 205 SER A N   1 
ATOM   1394 C CA  . SER A 1 206 ? 74.40620 27.67604 72.31060  1.000 41.78418 ? 205 SER A CA  1 
ATOM   1395 C C   . SER A 1 206 ? 73.94856 29.12164 72.34470  1.000 43.91602 ? 205 SER A C   1 
ATOM   1396 O O   . SER A 1 206 ? 72.98164 29.45660 73.03721  1.000 46.63396 ? 205 SER A O   1 
ATOM   1397 C CB  . SER A 1 206 ? 73.37112 26.81120 71.59771  1.000 38.99538 ? 205 SER A CB  1 
ATOM   1398 O OG  . SER A 1 206 ? 72.05980 27.21210 71.95076  1.000 40.82772 ? 205 SER A OG  1 
ATOM   1399 N N   . GLY A 1 207 ? 74.67802 29.98364 71.65138  1.000 42.00898 ? 206 GLY A N   1 
ATOM   1400 C CA  . GLY A 1 207 ? 74.29884 31.37486 71.56162  1.000 41.43973 ? 206 GLY A CA  1 
ATOM   1401 C C   . GLY A 1 207 ? 74.78229 32.29483 72.66478  1.000 42.61566 ? 206 GLY A C   1 
ATOM   1402 O O   . GLY A 1 207 ? 74.20642 33.37429 72.82725  1.000 48.07349 ? 206 GLY A O   1 
ATOM   1403 N N   . VAL A 1 208 ? 75.76638 31.90156 73.46563  1.000 42.92153 ? 207 VAL A N   1 
ATOM   1404 C CA  . VAL A 1 208 ? 76.48964 32.83221 74.33673  1.000 44.83805 ? 207 VAL A CA  1 
ATOM   1405 C C   . VAL A 1 208 ? 77.80263 33.19236 73.65357  1.000 43.19954 ? 207 VAL A C   1 
ATOM   1406 O O   . VAL A 1 208 ? 78.58540 32.28459 73.33067  1.000 48.09273 ? 207 VAL A O   1 
ATOM   1407 C CB  . VAL A 1 208 ? 76.72027 32.24646 75.74266  1.000 34.93033 ? 207 VAL A CB  1 
ATOM   1408 C CG1 . VAL A 1 208 ? 77.84554 32.95862 76.43522  1.000 36.13198 ? 207 VAL A CG1 1 
ATOM   1409 C CG2 . VAL A 1 208 ? 75.46312 32.37435 76.59362  1.000 31.85514 ? 207 VAL A CG2 1 
ATOM   1410 N N   . PRO A 1 209 ? 78.09792 34.47908 73.41786  1.000 38.67347 ? 208 PRO A N   1 
ATOM   1411 C CA  . PRO A 1 209 ? 79.31945 34.85378 72.69013  1.000 37.93648 ? 208 PRO A CA  1 
ATOM   1412 C C   . PRO A 1 209 ? 80.60083 34.44897 73.40906  1.000 39.82270 ? 208 PRO A C   1 
ATOM   1413 O O   . PRO A 1 209 ? 80.73807 34.65244 74.61619  1.000 42.59499 ? 208 PRO A O   1 
ATOM   1414 C CB  . PRO A 1 209 ? 79.20717 36.37752 72.58038  1.000 41.65724 ? 208 PRO A CB  1 
ATOM   1415 C CG  . PRO A 1 209 ? 77.74999 36.67609 72.74405  1.000 32.76910 ? 208 PRO A CG  1 
ATOM   1416 C CD  . PRO A 1 209 ? 77.25053 35.65397 73.70204  1.000 40.13082 ? 208 PRO A CD  1 
ATOM   1417 N N   . ASP A 1 210 ? 81.56467 33.91664 72.63179  1.000 39.28936 ? 209 ASP A N   1 
ATOM   1418 C CA  . ASP A 1 210 ? 82.87406 33.42875 73.09940  1.000 38.69441 ? 209 ASP A CA  1 
ATOM   1419 C C   . ASP A 1 210 ? 83.66594 34.49417 73.85757  1.000 39.66812 ? 209 ASP A C   1 
ATOM   1420 O O   . ASP A 1 210 ? 84.75062 34.19306 74.36803  1.000 40.32726 ? 209 ASP A O   1 
ATOM   1421 C CB  . ASP A 1 210 ? 83.68759 32.92258 71.88651  1.000 41.06606 ? 209 ASP A CB  1 
ATOM   1422 C CG  . ASP A 1 210 ? 84.62395 31.74748 72.21052  1.000 51.44349 ? 209 ASP A CG  1 
ATOM   1423 O OD1 . ASP A 1 210 ? 84.14981 30.77073 72.82214  1.000 57.48090 ? 209 ASP A OD1 1 
ATOM   1424 O OD2 . ASP A 1 210 ? 85.81110 31.75429 71.78805  1.000 45.06342 ? 209 ASP A OD2 1 
ATOM   1425 N N   . ARG A 1 211 ? 83.16328 35.72946 73.93657  1.000 43.06746 ? 210 ARG A N   1 
ATOM   1426 C CA  . ARG A 1 211 ? 83.77862 36.75433 74.77161  1.000 42.80767 ? 210 ARG A CA  1 
ATOM   1427 C C   . ARG A 1 211 ? 83.42133 36.60812 76.24488  1.000 45.18405 ? 210 ARG A C   1 
ATOM   1428 O O   . ARG A 1 211 ? 84.04333 37.27043 77.08623  1.000 41.99830 ? 210 ARG A O   1 
ATOM   1429 C CB  . ARG A 1 211 ? 83.34392 38.13191 74.29574  1.000 38.97407 ? 210 ARG A CB  1 
ATOM   1430 C CG  . ARG A 1 211 ? 81.85073 38.31407 74.33776  1.000 37.67048 ? 210 ARG A CG  1 
ATOM   1431 C CD  . ARG A 1 211 ? 81.39848 39.27974 73.24560  1.000 45.21980 ? 210 ARG A CD  1 
ATOM   1432 N NE  . ARG A 1 211 ? 80.05087 39.78477 73.48524  1.000 36.37100 ? 210 ARG A NE  1 
ATOM   1433 C CZ  . ARG A 1 211 ? 79.77211 40.71007 74.39475  1.000 39.28686 ? 210 ARG A CZ  1 
ATOM   1434 N NH1 . ARG A 1 211 ? 80.75677 41.22285 75.13074  1.000 41.02788 ? 210 ARG A NH1 1 
ATOM   1435 N NH2 . ARG A 1 211 ? 78.52280 41.12754 74.57093  1.000 33.16982 ? 210 ARG A NH2 1 
ATOM   1436 N N   . PHE A 1 212 ? 82.43036 35.77549 76.56998  1.000 44.66677 ? 211 PHE A N   1 
ATOM   1437 C CA  . PHE A 1 212 ? 82.17643 35.36468 77.94119  1.000 38.76400 ? 211 PHE A CA  1 
ATOM   1438 C C   . PHE A 1 212 ? 82.99337 34.10191 78.17389  1.000 38.70427 ? 211 PHE A C   1 
ATOM   1439 O O   . PHE A 1 212 ? 82.88342 33.14209 77.41302  1.000 43.07374 ? 211 PHE A O   1 
ATOM   1440 C CB  . PHE A 1 212 ? 80.68774 35.09042 78.17457  1.000 36.79416 ? 211 PHE A CB  1 
ATOM   1441 C CG  . PHE A 1 212 ? 79.83336 36.32837 78.28593  1.000 35.31800 ? 211 PHE A CG  1 
ATOM   1442 C CD1 . PHE A 1 212 ? 79.33728 36.73737 79.51468  1.000 36.80715 ? 211 PHE A CD1 1 
ATOM   1443 C CD2 . PHE A 1 212 ? 79.50138 37.06297 77.16355  1.000 35.45531 ? 211 PHE A CD2 1 
ATOM   1444 C CE1 . PHE A 1 212 ? 78.53795 37.87220 79.62287  1.000 36.30882 ? 211 PHE A CE1 1 
ATOM   1445 C CE2 . PHE A 1 212 ? 78.70759 38.19952 77.26129  1.000 37.17886 ? 211 PHE A CE2 1 
ATOM   1446 C CZ  . PHE A 1 212 ? 78.21904 38.60222 78.49128  1.000 35.68679 ? 211 PHE A CZ  1 
ATOM   1447 N N   . SER A 1 213 ? 83.82554 34.10634 79.19806  1.000 38.00553 ? 212 SER A N   1 
ATOM   1448 C CA  . SER A 1 213 ? 84.77747 33.02796 79.39932  1.000 34.40446 ? 212 SER A CA  1 
ATOM   1449 C C   . SER A 1 213 ? 84.73100 32.54946 80.83801  1.000 34.72168 ? 212 SER A C   1 
ATOM   1450 O O   . SER A 1 213 ? 84.66584 33.36442 81.76668  1.000 28.25674 ? 212 SER A O   1 
ATOM   1451 C CB  . SER A 1 213 ? 86.18159 33.46179 79.05077  1.000 38.15342 ? 212 SER A CB  1 
ATOM   1452 O OG  . SER A 1 213 ? 86.98876 32.32543 78.85052  1.000 43.43411 ? 212 SER A OG  1 
ATOM   1453 N N   . GLY A 1 214 ? 84.80971 31.22631 81.01303  1.000 37.79836 ? 213 GLY A N   1 
ATOM   1454 C CA  . GLY A 1 214 ? 84.76008 30.60012 82.32211  1.000 27.10220 ? 213 GLY A CA  1 
ATOM   1455 C C   . GLY A 1 214 ? 86.09589 29.96569 82.64521  1.000 24.49772 ? 213 GLY A C   1 
ATOM   1456 O O   . GLY A 1 214 ? 86.80656 29.50536 81.75706  1.000 32.82839 ? 213 GLY A O   1 
ATOM   1457 N N   . SER A 1 215 ? 86.44615 29.95706 83.92134  1.000 26.54981 ? 214 SER A N   1 
ATOM   1458 C CA  . SER A 1 215 ? 87.71282 29.37889 84.34279  1.000 30.59051 ? 214 SER A CA  1 
ATOM   1459 C C   . SER A 1 215 ? 87.67599 29.15677 85.84490  1.000 39.48843 ? 214 SER A C   1 
ATOM   1460 O O   . SER A 1 215 ? 86.82415 29.69962 86.55168  1.000 38.13077 ? 214 SER A O   1 
ATOM   1461 C CB  . SER A 1 215 ? 88.89379 30.27542 83.97944  1.000 36.56902 ? 214 SER A CB  1 
ATOM   1462 O OG  . SER A 1 215 ? 90.11589 29.57116 84.10598  1.000 39.70299 ? 214 SER A OG  1 
ATOM   1463 N N   . LYS A 1 216 ? 88.60780 28.33820 86.32213  1.000 38.82882 ? 215 LYS A N   1 
ATOM   1464 C CA  . LYS A 1 216 ? 88.62233 27.94908 87.72403  1.000 41.25333 ? 215 LYS A CA  1 
ATOM   1465 C C   . LYS A 1 216 ? 90.02772 27.48708 88.07349  1.000 45.84344 ? 215 LYS A C   1 
ATOM   1466 O O   . LYS A 1 216 ? 90.80305 27.08978 87.19945  1.000 49.35335 ? 215 LYS A O   1 
ATOM   1467 C CB  . LYS A 1 216 ? 87.58271 26.85168 87.99299  1.000 38.97010 ? 215 LYS A CB  1 
ATOM   1468 C CG  . LYS A 1 216 ? 87.59999 26.19797 89.35779  1.000 33.13163 ? 215 LYS A CG  1 
ATOM   1469 C CD  . LYS A 1 216 ? 86.77208 24.91321 89.34535  1.000 31.90205 ? 215 LYS A CD  1 
ATOM   1470 C CE  . LYS A 1 216 ? 87.62080 23.67714 89.05978  1.000 43.36431 ? 215 LYS A CE  1 
ATOM   1471 N NZ  . LYS A 1 216 ? 87.04821 22.43109 89.65308  1.000 37.88602 ? 215 LYS A NZ  1 
ATOM   1472 N N   . SER A 1 217 ? 90.36325 27.57880 89.35486  1.000 40.45539 ? 216 SER A N   1 
ATOM   1473 C CA  . SER A 1 217 ? 91.58982 26.94878 89.84090  1.000 53.12045 ? 216 SER A CA  1 
ATOM   1474 C C   . SER A 1 217 ? 91.45573 26.77012 91.34428  1.000 56.79512 ? 216 SER A C   1 
ATOM   1475 O O   . SER A 1 217 ? 91.27030 27.75170 92.07451  1.000 52.02906 ? 216 SER A O   1 
ATOM   1476 C CB  . SER A 1 217 ? 92.82766 27.77221 89.48345  1.000 43.09621 ? 216 SER A CB  1 
ATOM   1477 O OG  . SER A 1 217 ? 92.68709 29.11399 89.90252  1.000 56.16551 ? 216 SER A OG  1 
ATOM   1478 N N   . GLY A 1 218 ? 91.57141 25.52908 91.81058  1.000 57.43246 ? 217 GLY A N   1 
ATOM   1479 C CA  . GLY A 1 218 ? 91.32234 25.29698 93.22035  1.000 56.17940 ? 217 GLY A CA  1 
ATOM   1480 C C   . GLY A 1 218 ? 89.90439 25.70938 93.56917  1.000 53.43639 ? 217 GLY A C   1 
ATOM   1481 O O   . GLY A 1 218 ? 88.94231 25.32338 92.89309  1.000 47.80896 ? 217 GLY A O   1 
ATOM   1482 N N   . ASN A 1 219 ? 89.78085 26.54393 94.61056  1.000 51.76466 ? 218 ASN A N   1 
ATOM   1483 C CA  . ASN A 1 219 ? 88.50897 26.92595 95.21760  1.000 46.11178 ? 218 ASN A CA  1 
ATOM   1484 C C   . ASN A 1 219 ? 87.89710 28.20921 94.63135  1.000 44.65526 ? 218 ASN A C   1 
ATOM   1485 O O   . ASN A 1 219 ? 86.97656 28.77917 95.23512  1.000 44.46380 ? 218 ASN A O   1 
ATOM   1486 C CB  . ASN A 1 219 ? 88.70402 27.08614 96.73135  1.000 38.91164 ? 218 ASN A CB  1 
ATOM   1487 C CG  . ASN A 1 219 ? 88.73655 25.75398 97.46860  1.000 44.39160 ? 218 ASN A CG  1 
ATOM   1488 O OD1 . ASN A 1 219 ? 88.48363 24.69971 96.88598  1.000 46.76550 ? 218 ASN A OD1 1 
ATOM   1489 N ND2 . ASN A 1 219 ? 89.06455 25.79424 98.75597  1.000 47.88125 ? 218 ASN A ND2 1 
ATOM   1490 N N   . MET A 1 220 ? 88.36631 28.66193 93.47012  1.000 42.98087 ? 219 MET A N   1 
ATOM   1491 C CA  . MET A 1 220 ? 87.98514 29.96593 92.93002  1.000 43.08239 ? 219 MET A CA  1 
ATOM   1492 C C   . MET A 1 220 ? 87.78341 29.91635 91.42293  1.000 39.51333 ? 219 MET A C   1 
ATOM   1493 O O   . MET A 1 220 ? 88.70849 29.59157 90.66994  1.000 46.38892 ? 219 MET A O   1 
ATOM   1494 C CB  . MET A 1 220 ? 89.02334 31.01915 93.31042  1.000 50.44303 ? 219 MET A CB  1 
ATOM   1495 C CG  . MET A 1 220 ? 88.94507 32.27582 92.51282  1.000 42.82795 ? 219 MET A CG  1 
ATOM   1496 S SD  . MET A 1 220 ? 89.97656 33.49264 93.31573  1.000 54.45459 ? 219 MET A SD  1 
ATOM   1497 C CE  . MET A 1 220 ? 90.40071 34.54866 91.92930  1.000 44.44213 ? 219 MET A CE  1 
ATOM   1498 N N   . ALA A 1 221 ? 86.58087 30.26282 90.99189  1.000 32.08787 ? 220 ALA A N   1 
ATOM   1499 C CA  . ALA A 1 221 ? 86.21255 30.33955 89.59120  1.000 32.56781 ? 220 ALA A CA  1 
ATOM   1500 C C   . ALA A 1 221 ? 86.31206 31.77954 89.09520  1.000 38.83804 ? 220 ALA A C   1 
ATOM   1501 O O   . ALA A 1 221 ? 86.33141 32.73153 89.87951  1.000 36.23520 ? 220 ALA A O   1 
ATOM   1502 C CB  . ALA A 1 221 ? 84.79783 29.79543 89.38302  1.000 31.34473 ? 220 ALA A CB  1 
ATOM   1503 N N   . SER A 1 222 ? 86.40002 31.92993 87.77130  1.000 35.47681 ? 221 SER A N   1 
ATOM   1504 C CA  . SER A 1 222 ? 86.51374 33.24405 87.16692  1.000 29.89036 ? 221 SER A CA  1 
ATOM   1505 C C   . SER A 1 222 ? 85.65205 33.33406 85.91999  1.000 34.63402 ? 221 SER A C   1 
ATOM   1506 O O   . SER A 1 222 ? 85.53304 32.36981 85.16110  1.000 36.05597 ? 221 SER A O   1 
ATOM   1507 C CB  . SER A 1 222 ? 87.96914 33.56159 86.82092  1.000 35.95553 ? 221 SER A CB  1 
ATOM   1508 O OG  . SER A 1 222 ? 88.79582 33.44730 87.97191  1.000 37.42051 ? 221 SER A OG  1 
ATOM   1509 N N   . LEU A 1 223 ? 84.99791 34.47942 85.75845  1.000 38.80091 ? 222 LEU A N   1 
ATOM   1510 C CA  . LEU A 1 223 ? 84.31152 34.84928 84.53110  1.000 34.13487 ? 222 LEU A CA  1 
ATOM   1511 C C   . LEU A 1 223 ? 85.09971 35.98008 83.90827  1.000 28.69901 ? 222 LEU A C   1 
ATOM   1512 O O   . LEU A 1 223 ? 85.48417 36.91242 84.60866  1.000 32.56482 ? 222 LEU A O   1 
ATOM   1513 C CB  . LEU A 1 223 ? 82.88646 35.32099 84.81358  1.000 34.26984 ? 222 LEU A CB  1 
ATOM   1514 C CG  . LEU A 1 223 ? 82.01860 35.71293 83.62020  1.000 32.92203 ? 222 LEU A CG  1 
ATOM   1515 C CD1 . LEU A 1 223 ? 81.95727 34.57900 82.61107  1.000 32.13455 ? 222 LEU A CD1 1 
ATOM   1516 C CD2 . LEU A 1 223 ? 80.61517 36.06080 84.09414  1.000 32.01174 ? 222 LEU A CD2 1 
ATOM   1517 N N   . THR A 1 224 ? 85.27984 35.95497 82.59481  1.000 33.16902 ? 223 THR A N   1 
ATOM   1518 C CA  . THR A 1 224 ? 86.00095 37.03295 81.92352  1.000 38.55214 ? 223 THR A CA  1 
ATOM   1519 C C   . THR A 1 224 ? 85.18144 37.49102 80.73416  1.000 36.10057 ? 223 THR A C   1 
ATOM   1520 O O   . THR A 1 224 ? 84.92118 36.70624 79.81481  1.000 36.54581 ? 223 THR A O   1 
ATOM   1521 C CB  . THR A 1 224 ? 87.39751 36.61083 81.45886  1.000 33.50557 ? 223 THR A CB  1 
ATOM   1522 O OG1 . THR A 1 224 ? 88.26222 36.47633 82.58467  1.000 30.20849 ? 223 THR A OG1 1 
ATOM   1523 C CG2 . THR A 1 224 ? 87.97370 37.68811 80.57913  1.000 33.44420 ? 223 THR A CG2 1 
ATOM   1524 N N   . VAL A 1 225 ? 84.78270 38.75518 80.75154  1.000 30.41590 ? 224 VAL A N   1 
ATOM   1525 C CA  . VAL A 1 225 ? 84.05560 39.35311 79.64340  1.000 38.89112 ? 224 VAL A CA  1 
ATOM   1526 C C   . VAL A 1 225 ? 85.06944 40.13523 78.82688  1.000 39.72444 ? 224 VAL A C   1 
ATOM   1527 O O   . VAL A 1 225 ? 85.53434 41.19444 79.24908  1.000 41.70066 ? 224 VAL A O   1 
ATOM   1528 C CB  . VAL A 1 225 ? 82.90922 40.24516 80.11586  1.000 31.36080 ? 224 VAL A CB  1 
ATOM   1529 C CG1 . VAL A 1 225 ? 81.99824 40.55653 78.94639  1.000 33.13877 ? 224 VAL A CG1 1 
ATOM   1530 C CG2 . VAL A 1 225 ? 82.15483 39.58991 81.26274  1.000 30.61497 ? 224 VAL A CG2 1 
ATOM   1531 N N   . SER A 1 226 ? 85.45986 39.58270 77.68457  1.000 39.05565 ? 225 SER A N   1 
ATOM   1532 C CA  . SER A 1 226 ? 86.28358 40.32267 76.74290  1.000 41.64109 ? 225 SER A CA  1 
ATOM   1533 C C   . SER A 1 226 ? 85.44883 41.29114 75.90563  1.000 44.37178 ? 225 SER A C   1 
ATOM   1534 O O   . SER A 1 226 ? 84.27991 41.03296 75.59466  1.000 49.60429 ? 225 SER A O   1 
ATOM   1535 C CB  . SER A 1 226 ? 87.03247 39.35506 75.83595  1.000 41.68874 ? 225 SER A CB  1 
ATOM   1536 O OG  . SER A 1 226 ? 88.18732 38.88229 76.49865  1.000 47.24790 ? 225 SER A OG  1 
ATOM   1537 N N   . GLY A 1 227 ? 86.06483 42.42449 75.55266  1.000 49.68754 ? 226 GLY A N   1 
ATOM   1538 C CA  . GLY A 1 227 ? 85.45775 43.41286 74.67684  1.000 43.50496 ? 226 GLY A CA  1 
ATOM   1539 C C   . GLY A 1 227 ? 84.03999 43.78647 75.03927  1.000 46.96877 ? 226 GLY A C   1 
ATOM   1540 O O   . GLY A 1 227 ? 83.11650 43.49324 74.27675  1.000 47.23371 ? 226 GLY A O   1 
ATOM   1541 N N   . LEU A 1 228 ? 83.86121 44.43501 76.19221  1.000 47.38491 ? 227 LEU A N   1 
ATOM   1542 C CA  . LEU A 1 228 ? 82.55034 44.81146 76.71314  1.000 44.42562 ? 227 LEU A CA  1 
ATOM   1543 C C   . LEU A 1 228 ? 81.62567 45.47673 75.70185  1.000 45.99393 ? 227 LEU A C   1 
ATOM   1544 O O   . LEU A 1 228 ? 82.05758 45.98190 74.66005  1.000 50.16829 ? 227 LEU A O   1 
ATOM   1545 C CB  . LEU A 1 228 ? 82.72878 45.75243 77.89375  1.000 46.98643 ? 227 LEU A CB  1 
ATOM   1546 C CG  . LEU A 1 228 ? 83.32128 45.18736 79.16611  1.000 41.81221 ? 227 LEU A CG  1 
ATOM   1547 C CD1 . LEU A 1 228 ? 83.66204 46.35006 80.03742  1.000 50.71606 ? 227 LEU A CD1 1 
ATOM   1548 C CD2 . LEU A 1 228 ? 82.25483 44.37407 79.84228  1.000 40.92011 ? 227 LEU A CD2 1 
ATOM   1549 N N   . GLN A 1 229 ? 80.33672 45.49271 76.02044  1.000 46.30044 ? 228 GLN A N   1 
ATOM   1550 C CA  . GLN A 1 229 ? 79.32862 46.00189 75.10998  1.000 44.68498 ? 228 GLN A CA  1 
ATOM   1551 C C   . GLN A 1 229 ? 78.25196 46.61620 75.98041  1.000 40.43424 ? 228 GLN A C   1 
ATOM   1552 O O   . GLN A 1 229 ? 78.15724 46.32088 77.17262  1.000 45.05894 ? 228 GLN A O   1 
ATOM   1553 C CB  . GLN A 1 229 ? 78.75604 44.89433 74.21579  1.000 44.02304 ? 228 GLN A CB  1 
ATOM   1554 C CG  . GLN A 1 229 ? 79.83325 43.95523 73.65376  1.000 50.13324 ? 228 GLN A CG  1 
ATOM   1555 C CD  . GLN A 1 229 ? 80.19725 44.16477 72.20618  1.000 56.01063 ? 228 GLN A CD  1 
ATOM   1556 O OE1 . GLN A 1 229 ? 79.91716 45.21430 71.62842  1.000 74.55578 ? 228 GLN A OE1 1 
ATOM   1557 N NE2 . GLN A 1 229 ? 80.88789 43.18302 71.62539  1.000 66.21648 ? 228 GLN A NE2 1 
ATOM   1558 N N   . ALA A 1 230 ? 77.47240 47.51326 75.38899  1.000 38.79907 ? 229 ALA A N   1 
ATOM   1559 C CA  . ALA A 1 230 ? 76.46045 48.21082 76.16841  1.000 37.86338 ? 229 ALA A CA  1 
ATOM   1560 C C   . ALA A 1 230 ? 75.48397 47.22646 76.78200  1.000 39.63918 ? 229 ALA A C   1 
ATOM   1561 O O   . ALA A 1 230 ? 75.15688 47.31814 77.97102  1.000 37.19789 ? 229 ALA A O   1 
ATOM   1562 C CB  . ALA A 1 230 ? 75.72598 49.21134 75.27996  1.000 48.94610 ? 229 ALA A CB  1 
ATOM   1563 N N   . GLU A 1 231 ? 75.05546 46.24004 75.99539  1.000 42.52080 ? 230 GLU A N   1 
ATOM   1564 C CA  . GLU A 1 231 ? 74.15753 45.21585 76.49274  1.000 40.67194 ? 230 GLU A CA  1 
ATOM   1565 C C   . GLU A 1 231 ? 74.78781 44.39805 77.60977  1.000 39.61939 ? 230 GLU A C   1 
ATOM   1566 O O   . GLU A 1 231 ? 74.06306 43.70604 78.33367  1.000 39.98589 ? 230 GLU A O   1 
ATOM   1567 C CB  . GLU A 1 231 ? 73.74650 44.29674 75.34519  1.000 32.71146 ? 230 GLU A CB  1 
ATOM   1568 N N   . ASP A 1 232 ? 76.10113 44.49748 77.80300  1.000 35.91115 ? 231 ASP A N   1 
ATOM   1569 C CA  . ASP A 1 232 ? 76.77465 43.62639 78.74683  1.000 36.00101 ? 231 ASP A CA  1 
ATOM   1570 C C   . ASP A 1 232 ? 76.64564 44.08206 80.18760  1.000 37.19832 ? 231 ASP A C   1 
ATOM   1571 O O   . ASP A 1 232 ? 77.13215 43.38420 81.08158  1.000 32.31669 ? 231 ASP A O   1 
ATOM   1572 C CB  . ASP A 1 232 ? 78.24924 43.53095 78.38587  1.000 40.48360 ? 231 ASP A CB  1 
ATOM   1573 C CG  . ASP A 1 232 ? 78.51054 42.54912 77.26572  1.000 45.47527 ? 231 ASP A CG  1 
ATOM   1574 O OD1 . ASP A 1 232 ? 79.66936 42.52353 76.78311  1.000 44.61208 ? 231 ASP A OD1 1 
ATOM   1575 O OD2 . ASP A 1 232 ? 77.57083 41.80727 76.87767  1.000 37.93315 ? 231 ASP A OD2 1 
ATOM   1576 N N   . GLU A 1 233 ? 75.95633 45.18437 80.45282  1.000 41.42123 ? 232 GLU A N   1 
ATOM   1577 C CA  . GLU A 1 233 ? 75.86744 45.68889 81.81740  1.000 44.80826 ? 232 GLU A CA  1 
ATOM   1578 C C   . GLU A 1 233 ? 74.75378 44.98108 82.58519  1.000 44.29629 ? 232 GLU A C   1 
ATOM   1579 O O   . GLU A 1 233 ? 73.57321 45.26347 82.35625  1.000 41.33604 ? 232 GLU A O   1 
ATOM   1580 C CB  . GLU A 1 233 ? 75.63735 47.19077 81.82604  1.000 41.51575 ? 232 GLU A CB  1 
ATOM   1581 C CG  . GLU A 1 233 ? 75.76436 47.67422 83.22996  1.000 47.36213 ? 232 GLU A CG  1 
ATOM   1582 C CD  . GLU A 1 233 ? 75.39549 49.10229 83.42123  1.000 59.10903 ? 232 GLU A CD  1 
ATOM   1583 O OE1 . GLU A 1 233 ? 75.89424 49.94158 82.63456  1.000 61.00215 ? 232 GLU A OE1 1 
ATOM   1584 O OE2 . GLU A 1 233 ? 74.63127 49.38383 84.37886  1.000 62.61054 ? 232 GLU A OE2 1 
ATOM   1585 N N   . ALA A 1 234 ? 75.11509 44.12018 83.54468  1.000 37.08135 ? 233 ALA A N   1 
ATOM   1586 C CA  . ALA A 1 234 ? 74.11298 43.33283 84.25728  1.000 34.53166 ? 233 ALA A CA  1 
ATOM   1587 C C   . ALA A 1 234 ? 74.62685 42.90692 85.63570  1.000 33.69194 ? 233 ALA A C   1 
ATOM   1588 O O   . ALA A 1 234 ? 75.77492 43.16246 86.00659  1.000 31.94966 ? 233 ALA A O   1 
ATOM   1589 C CB  . ALA A 1 234 ? 73.71989 42.11480 83.42882  1.000 32.80748 ? 233 ALA A CB  1 
ATOM   1590 N N   . ASP A 1 235 ? 73.75029 42.22907 86.38876  1.000 34.21168 ? 234 ASP A N   1 
ATOM   1591 C CA  . ASP A 1 235 ? 74.11798 41.51172 87.60898  1.000 31.76396 ? 234 ASP A CA  1 
ATOM   1592 C C   . ASP A 1 235 ? 74.56018 40.10258 87.21339  1.000 30.88801 ? 234 ASP A C   1 
ATOM   1593 O O   . ASP A 1 235 ? 73.89165 39.44536 86.40572  1.000 24.69347 ? 234 ASP A O   1 
ATOM   1594 C CB  . ASP A 1 235 ? 72.92774 41.41857 88.57246  1.000 33.37746 ? 234 ASP A CB  1 
ATOM   1595 C CG  . ASP A 1 235 ? 72.68730 42.69814 89.37925  1.000 36.94331 ? 234 ASP A CG  1 
ATOM   1596 O OD1 . ASP A 1 235 ? 73.62384 43.51175 89.54618  1.000 35.40486 ? 234 ASP A OD1 1 
ATOM   1597 O OD2 . ASP A 1 235 ? 71.53897 42.88962 89.85204  1.000 33.44514 ? 234 ASP A OD2 1 
ATOM   1598 N N   . TYR A 1 236 ? 75.68766 39.64536 87.76705  1.000 26.48027 ? 235 TYR A N   1 
ATOM   1599 C CA  . TYR A 1 236 ? 76.26571 38.35149 87.40794  1.000 26.62149 ? 235 TYR A CA  1 
ATOM   1600 C C   . TYR A 1 236 ? 76.37142 37.47615 88.64796  1.000 31.96717 ? 235 TYR A C   1 
ATOM   1601 O O   . TYR A 1 236 ? 77.12505 37.78939 89.57990  1.000 34.19003 ? 235 TYR A O   1 
ATOM   1602 C CB  . TYR A 1 236 ? 77.63769 38.51952 86.74658  1.000 28.30563 ? 235 TYR A CB  1 
ATOM   1603 C CG  . TYR A 1 236 ? 77.56471 39.03352 85.31255  1.000 30.23528 ? 235 TYR A CG  1 
ATOM   1604 C CD1 . TYR A 1 236 ? 77.57812 40.40822 85.03073  1.000 26.53576 ? 235 TYR A CD1 1 
ATOM   1605 C CD2 . TYR A 1 236 ? 77.46089 38.14723 84.24441  1.000 25.66255 ? 235 TYR A CD2 1 
ATOM   1606 C CE1 . TYR A 1 236 ? 77.50243 40.87592 83.72837  1.000 26.10382 ? 235 TYR A CE1 1 
ATOM   1607 C CE2 . TYR A 1 236 ? 77.37351 38.60931 82.93892  1.000 27.01038 ? 235 TYR A CE2 1 
ATOM   1608 C CZ  . TYR A 1 236 ? 77.40021 39.97025 82.68839  1.000 27.32266 ? 235 TYR A CZ  1 
ATOM   1609 O OH  . TYR A 1 236 ? 77.32049 40.40144 81.39027  1.000 26.71318 ? 235 TYR A OH  1 
ATOM   1610 N N   . TYR A 1 237 ? 75.64563 36.36545 88.64067  1.000 29.06503 ? 236 TYR A N   1 
ATOM   1611 C CA  . TYR A 1 237 ? 75.60752 35.44273 89.75919  1.000 27.31138 ? 236 TYR A CA  1 
ATOM   1612 C C   . TYR A 1 237 ? 76.36422 34.17430 89.42702  1.000 24.29217 ? 236 TYR A C   1 
ATOM   1613 O O   . TYR A 1 237 ? 76.22657 33.63539 88.33097  1.000 27.91499 ? 236 TYR A O   1 
ATOM   1614 C CB  . TYR A 1 237 ? 74.17476 35.08866 90.08782  1.000 27.02647 ? 236 TYR A CB  1 
ATOM   1615 C CG  . TYR A 1 237 ? 73.43344 36.22259 90.72181  1.000 28.75206 ? 236 TYR A CG  1 
ATOM   1616 C CD1 . TYR A 1 237 ? 72.89287 37.24389 89.95787  1.000 23.89103 ? 236 TYR A CD1 1 
ATOM   1617 C CD2 . TYR A 1 237 ? 73.26480 36.27001 92.09155  1.000 31.94498 ? 236 TYR A CD2 1 
ATOM   1618 C CE1 . TYR A 1 237 ? 72.20297 38.28796 90.55309  1.000 25.90323 ? 236 TYR A CE1 1 
ATOM   1619 C CE2 . TYR A 1 237 ? 72.58204 37.30875 92.69214  1.000 34.22239 ? 236 TYR A CE2 1 
ATOM   1620 C CZ  . TYR A 1 237 ? 72.05000 38.31013 91.92433  1.000 25.24292 ? 236 TYR A CZ  1 
ATOM   1621 O OH  . TYR A 1 237 ? 71.36714 39.32232 92.55908  1.000 36.81774 ? 236 TYR A OH  1 
ATOM   1622 N N   . CYS A 1 238 ? 77.12315 33.67674 90.39267  1.000 25.74341 ? 237 CYS A N   1 
ATOM   1623 C CA  . CYS A 1 238 ? 77.82123 32.41258 90.24729  1.000 29.92693 ? 237 CYS A CA  1 
ATOM   1624 C C   . CYS A 1 238 ? 77.16973 31.36626 91.14067  1.000 35.25952 ? 237 CYS A C   1 
ATOM   1625 O O   . CYS A 1 238 ? 76.58154 31.68526 92.18433  1.000 32.38986 ? 237 CYS A O   1 
ATOM   1626 C CB  . CYS A 1 238 ? 79.30567 32.54476 90.59603  1.000 35.13154 ? 237 CYS A CB  1 
ATOM   1627 S SG  . CYS A 1 238 ? 79.66370 32.50389 92.38522  1.000 45.55856 ? 237 CYS A SG  1 
ATOM   1628 N N   . SER A 1 239 ? 77.27542 30.11089 90.70390  1.000 37.91092 ? 238 SER A N   1 
ATOM   1629 C CA  . SER A 1 239 ? 76.69984 28.96727 91.39699  1.000 31.91133 ? 238 SER A CA  1 
ATOM   1630 C C   . SER A 1 239 ? 77.61139 27.76837 91.20995  1.000 32.91203 ? 238 SER A C   1 
ATOM   1631 O O   . SER A 1 239 ? 78.28247 27.63774 90.18308  1.000 32.54394 ? 238 SER A O   1 
ATOM   1632 C CB  . SER A 1 239 ? 75.31856 28.61777 90.86293  1.000 24.10791 ? 238 SER A CB  1 
ATOM   1633 O OG  . SER A 1 239 ? 75.43146 28.18203 89.53134  1.000 25.46932 ? 238 SER A OG  1 
ATOM   1634 N N   . SER A 1 240 ? 77.59687 26.87723 92.19696  1.000 35.96950 ? 239 SER A N   1 
ATOM   1635 C CA  . SER A 1 240 ? 78.29207 25.60104 92.12381  1.000 36.17727 ? 239 SER A CA  1 
ATOM   1636 C C   . SER A 1 240 ? 77.42155 24.52259 92.74628  1.000 36.40097 ? 239 SER A C   1 
ATOM   1637 O O   . SER A 1 240 ? 76.72618 24.76884 93.73403  1.000 37.13772 ? 239 SER A O   1 
ATOM   1638 C CB  . SER A 1 240 ? 79.64700 25.64724 92.84555  1.000 37.92578 ? 239 SER A CB  1 
ATOM   1639 O OG  . SER A 1 240 ? 80.11400 24.34046 93.15046  1.000 39.27753 ? 239 SER A OG  1 
ATOM   1640 N N   . TYR A 1 241 ? 77.45239 23.33427 92.15915  1.000 37.91259 ? 240 TYR A N   1 
ATOM   1641 C CA  . TYR A 1 241 ? 76.99978 22.15735 92.88282  1.000 36.97603 ? 240 TYR A CA  1 
ATOM   1642 C C   . TYR A 1 241 ? 77.80178 22.03366 94.17330  1.000 39.65769 ? 240 TYR A C   1 
ATOM   1643 O O   . TYR A 1 241 ? 79.01235 22.27990 94.19459  1.000 42.15911 ? 240 TYR A O   1 
ATOM   1644 C CB  . TYR A 1 241 ? 77.16946 20.92002 91.99887  1.000 36.45566 ? 240 TYR A CB  1 
ATOM   1645 C CG  . TYR A 1 241 ? 76.76286 19.60769 92.62103  1.000 36.43968 ? 240 TYR A CG  1 
ATOM   1646 C CD1 . TYR A 1 241 ? 75.42931 19.29677 92.83973  1.000 37.29025 ? 240 TYR A CD1 1 
ATOM   1647 C CD2 . TYR A 1 241 ? 77.72368 18.66259 92.96893  1.000 39.69855 ? 240 TYR A CD2 1 
ATOM   1648 C CE1 . TYR A 1 241 ? 75.06597 18.07427 93.40048  1.000 40.13492 ? 240 TYR A CE1 1 
ATOM   1649 C CE2 . TYR A 1 241 ? 77.37692 17.44633 93.53093  1.000 34.16951 ? 240 TYR A CE2 1 
ATOM   1650 C CZ  . TYR A 1 241 ? 76.05466 17.15453 93.74295  1.000 37.56486 ? 240 TYR A CZ  1 
ATOM   1651 O OH  . TYR A 1 241 ? 75.72881 15.94219 94.29492  1.000 34.72654 ? 240 TYR A OH  1 
ATOM   1652 N N   . ALA A 1 242 ? 77.12824 21.64576 95.25649  1.000 36.54780 ? 241 ALA A N   1 
ATOM   1653 C CA  . ALA A 1 242 ? 77.74298 21.65115 96.58074  1.000 33.82300 ? 241 ALA A CA  1 
ATOM   1654 C C   . ALA A 1 242 ? 77.57326 20.30355 97.27821  1.000 39.26854 ? 241 ALA A C   1 
ATOM   1655 O O   . ALA A 1 242 ? 77.47338 20.22294 98.50747  1.000 30.88832 ? 241 ALA A O   1 
ATOM   1656 C CB  . ALA A 1 242 ? 77.16321 22.77584 97.43622  1.000 38.61033 ? 241 ALA A CB  1 
ATOM   1657 N N   . GLY A 1 243 ? 77.56335 19.23419 96.50017  1.000 46.28122 ? 242 GLY A N   1 
ATOM   1658 C CA  . GLY A 1 243 ? 77.46170 17.90297 97.04204  1.000 36.56956 ? 242 GLY A CA  1 
ATOM   1659 C C   . GLY A 1 243 ? 76.04543 17.50828 97.37756  1.000 35.64772 ? 242 GLY A C   1 
ATOM   1660 O O   . GLY A 1 243 ? 75.08872 18.27097 97.28743  1.000 35.81552 ? 242 GLY A O   1 
ATOM   1661 N N   . SER A 1 244 ? 75.95087 16.27497 97.85100  1.000 39.39318 ? 243 SER A N   1 
ATOM   1662 C CA  . SER A 1 244 ? 74.66953 15.61224 98.04377  1.000 41.89198 ? 243 SER A CA  1 
ATOM   1663 C C   . SER A 1 244 ? 73.76624 16.34498 99.04014  1.000 38.74761 ? 243 SER A C   1 
ATOM   1664 O O   . SER A 1 244 ? 72.54494 16.38641 98.85550  1.000 39.31620 ? 243 SER A O   1 
ATOM   1665 C CB  . SER A 1 244 ? 74.95039 14.16911 98.44720  1.000 43.43675 ? 243 SER A CB  1 
ATOM   1666 O OG  . SER A 1 244 ? 76.10566 14.12676 99.27924  1.000 40.34227 ? 243 SER A OG  1 
ATOM   1667 N N   . TYR A 1 245 ? 74.33017 16.90423 100.11351 1.000 39.90017 ? 244 TYR A N   1 
ATOM   1668 C CA  . TYR A 1 245 ? 73.49156 17.45736 101.18018 1.000 42.41198 ? 244 TYR A CA  1 
ATOM   1669 C C   . TYR A 1 245 ? 72.95551 18.84790 100.84583 1.000 42.52141 ? 244 TYR A C   1 
ATOM   1670 O O   . TYR A 1 245 ? 71.75297 19.10812 100.98265 1.000 41.84733 ? 244 TYR A O   1 
ATOM   1671 C CB  . TYR A 1 245 ? 74.27028 17.52865 102.48734 1.000 45.10006 ? 244 TYR A CB  1 
ATOM   1672 C CG  . TYR A 1 245 ? 73.51364 18.23221 103.59378 1.000 52.90062 ? 244 TYR A CG  1 
ATOM   1673 C CD1 . TYR A 1 245 ? 74.14360 19.18862 104.40245 1.000 52.03084 ? 244 TYR A CD1 1 
ATOM   1674 C CD2 . TYR A 1 245 ? 72.17162 17.93069 103.84426 1.000 52.35634 ? 244 TYR A CD2 1 
ATOM   1675 C CE1 . TYR A 1 245 ? 73.45759 19.81932 105.42435 1.000 49.10688 ? 244 TYR A CE1 1 
ATOM   1676 C CE2 . TYR A 1 245 ? 71.47719 18.55872 104.86796 1.000 56.95832 ? 244 TYR A CE2 1 
ATOM   1677 C CZ  . TYR A 1 245 ? 72.12402 19.49789 105.65348 1.000 54.62076 ? 244 TYR A CZ  1 
ATOM   1678 O OH  . TYR A 1 245 ? 71.43205 20.11724 106.66873 1.000 56.75514 ? 244 TYR A OH  1 
ATOM   1679 N N   . ASN A 1 246 ? 73.83085 19.76548 100.44592 1.000 35.44075 ? 245 ASN A N   1 
ATOM   1680 C CA  . ASN A 1 246 ? 73.39235 21.12490 100.14768 1.000 41.68688 ? 245 ASN A CA  1 
ATOM   1681 C C   . ASN A 1 246 ? 72.89344 21.31607 98.71257  1.000 36.12323 ? 245 ASN A C   1 
ATOM   1682 O O   . ASN A 1 246 ? 72.15346 22.27067 98.45875  1.000 36.42024 ? 245 ASN A O   1 
ATOM   1683 C CB  . ASN A 1 246 ? 74.53180 22.10221 100.45166 1.000 35.34053 ? 245 ASN A CB  1 
ATOM   1684 C CG  . ASN A 1 246 ? 74.84484 22.16752 101.93310 1.000 33.28058 ? 245 ASN A CG  1 
ATOM   1685 O OD1 . ASN A 1 246 ? 73.93916 22.16043 102.76854 1.000 25.78460 ? 245 ASN A OD1 1 
ATOM   1686 N ND2 . ASN A 1 246 ? 76.12519 22.21368 102.26761 1.000 35.35768 ? 245 ASN A ND2 1 
ATOM   1687 N N   . PHE A 1 247 ? 73.25467 20.41752 97.78915  1.000 38.78377 ? 246 PHE A N   1 
ATOM   1688 C CA  . PHE A 1 247 ? 72.96833 20.51294 96.35651  1.000 37.59666 ? 246 PHE A CA  1 
ATOM   1689 C C   . PHE A 1 247 ? 73.61885 21.72709 95.70000  1.000 34.48142 ? 246 PHE A C   1 
ATOM   1690 O O   . PHE A 1 247 ? 74.74734 21.62293 95.21769  1.000 33.74517 ? 246 PHE A O   1 
ATOM   1691 C CB  . PHE A 1 247 ? 71.46471 20.52238 96.07242  1.000 39.24018 ? 246 PHE A CB  1 
ATOM   1692 C CG  . PHE A 1 247 ? 71.12513 20.10862 94.66082  1.000 43.71077 ? 246 PHE A CG  1 
ATOM   1693 C CD1 . PHE A 1 247 ? 70.51915 20.99726 93.78351  1.000 40.20808 ? 246 PHE A CD1 1 
ATOM   1694 C CD2 . PHE A 1 247 ? 71.44361 18.83598 94.19980  1.000 38.34885 ? 246 PHE A CD2 1 
ATOM   1695 C CE1 . PHE A 1 247 ? 70.22028 20.60955 92.47926  1.000 38.62670 ? 246 PHE A CE1 1 
ATOM   1696 C CE2 . PHE A 1 247 ? 71.14506 18.45117 92.89847  1.000 32.82760 ? 246 PHE A CE2 1 
ATOM   1697 C CZ  . PHE A 1 247 ? 70.54218 19.33927 92.04109  1.000 33.37707 ? 246 PHE A CZ  1 
ATOM   1698 N N   . TYR A 1 248 ? 72.91815 22.86000 95.62938  1.000 35.85896 ? 247 TYR A N   1 
ATOM   1699 C CA  . TYR A 1 248 ? 73.48148 24.09843 95.10376  1.000 32.10250 ? 247 TYR A CA  1 
ATOM   1700 C C   . TYR A 1 248 ? 73.83407 25.14359 96.16299  1.000 38.63690 ? 247 TYR A C   1 
ATOM   1701 O O   . TYR A 1 248 ? 73.26039 25.17837 97.25424  1.000 45.19458 ? 247 TYR A O   1 
ATOM   1702 C CB  . TYR A 1 248 ? 72.52819 24.74651 94.10204  1.000 32.17532 ? 247 TYR A CB  1 
ATOM   1703 C CG  . TYR A 1 248 ? 72.84402 24.41096 92.68443  1.000 35.75203 ? 247 TYR A CG  1 
ATOM   1704 C CD1 . TYR A 1 248 ? 73.67542 23.35231 92.36202  1.000 37.11795 ? 247 TYR A CD1 1 
ATOM   1705 C CD2 . TYR A 1 248 ? 72.49878 25.29252 91.68459  1.000 37.18645 ? 247 TYR A CD2 1 
ATOM   1706 C CE1 . TYR A 1 248 ? 74.02485 23.10459 91.03678  1.000 32.92564 ? 247 TYR A CE1 1 
ATOM   1707 C CE2 . TYR A 1 248 ? 72.84457 25.06648 90.37313  1.000 37.88260 ? 247 TYR A CE2 1 
ATOM   1708 C CZ  . TYR A 1 248 ? 73.60095 23.97681 90.05131  1.000 36.28123 ? 247 TYR A CZ  1 
ATOM   1709 O OH  . TYR A 1 248 ? 73.92605 23.79504 88.72964  1.000 44.44710 ? 247 TYR A OH  1 
ATOM   1710 N N   . VAL A 1 249 ? 74.74394 26.05473 95.78147  1.000 36.38086 ? 248 VAL A N   1 
ATOM   1711 C CA  . VAL A 1 249 ? 74.99276 27.30875 96.49152  1.000 39.91916 ? 248 VAL A CA  1 
ATOM   1712 C C   . VAL A 1 249 ? 75.33425 28.40891 95.48563  1.000 38.00683 ? 248 VAL A C   1 
ATOM   1713 O O   . VAL A 1 249 ? 75.86432 28.14318 94.40186  1.000 31.26524 ? 248 VAL A O   1 
ATOM   1714 C CB  . VAL A 1 249 ? 76.11947 27.16680 97.53480  1.000 34.91639 ? 248 VAL A CB  1 
ATOM   1715 C CG1 . VAL A 1 249 ? 75.63682 26.38902 98.75551  1.000 36.44381 ? 248 VAL A CG1 1 
ATOM   1716 C CG2 . VAL A 1 249 ? 77.30860 26.48787 96.91111  1.000 38.20141 ? 248 VAL A CG2 1 
ATOM   1717 N N   . PHE A 1 250 ? 75.05905 29.66367 95.86836  1.000 38.14389 ? 249 PHE A N   1 
ATOM   1718 C CA  . PHE A 1 250 ? 75.29387 30.81659 95.00210  1.000 37.66985 ? 249 PHE A CA  1 
ATOM   1719 C C   . PHE A 1 250 ? 76.15227 31.85700 95.70800  1.000 33.48213 ? 249 PHE A C   1 
ATOM   1720 O O   . PHE A 1 250 ? 76.30819 31.84419 96.93046  1.000 36.21999 ? 249 PHE A O   1 
ATOM   1721 C CB  . PHE A 1 250 ? 73.98546 31.51205 94.55807  1.000 36.15212 ? 249 PHE A CB  1 
ATOM   1722 C CG  . PHE A 1 250 ? 73.14163 30.71302 93.59486  1.000 33.72710 ? 249 PHE A CG  1 
ATOM   1723 C CD1 . PHE A 1 250 ? 72.35702 29.66533 94.04306  1.000 35.15024 ? 249 PHE A CD1 1 
ATOM   1724 C CD2 . PHE A 1 250 ? 73.09416 31.03908 92.25756  1.000 32.22317 ? 249 PHE A CD2 1 
ATOM   1725 C CE1 . PHE A 1 250 ? 71.57081 28.95206 93.17146  1.000 31.41669 ? 249 PHE A CE1 1 
ATOM   1726 C CE2 . PHE A 1 250 ? 72.29127 30.32294 91.38639  1.000 26.35645 ? 249 PHE A CE2 1 
ATOM   1727 C CZ  . PHE A 1 250 ? 71.53891 29.28588 91.84420  1.000 24.73138 ? 249 PHE A CZ  1 
ATOM   1728 N N   . GLY A 1 251 ? 76.69047 32.78395 94.90030  1.000 32.51318 ? 250 GLY A N   1 
ATOM   1729 C CA  . GLY A 1 251 ? 77.25888 34.01611 95.40699  1.000 36.04002 ? 250 GLY A CA  1 
ATOM   1730 C C   . GLY A 1 251 ? 76.18193 35.07246 95.51208  1.000 34.40883 ? 250 GLY A C   1 
ATOM   1731 O O   . GLY A 1 251 ? 75.04427 34.81067 95.13406  1.000 32.34598 ? 250 GLY A O   1 
ATOM   1732 N N   . ASN A 1 252 ? 76.53771 36.23810 96.08075  1.000 37.76677 ? 251 ASN A N   1 
ATOM   1733 C CA  . ASN A 1 252 ? 75.56356 37.32308 96.23701  1.000 30.76335 ? 251 ASN A CA  1 
ATOM   1734 C C   . ASN A 1 252 ? 75.40342 38.21047 95.00225  1.000 34.93256 ? 251 ASN A C   1 
ATOM   1735 O O   . ASN A 1 252 ? 74.53599 39.09756 95.01062  1.000 35.89908 ? 251 ASN A O   1 
ATOM   1736 C CB  . ASN A 1 252 ? 75.91097 38.20070 97.43567  1.000 36.83103 ? 251 ASN A CB  1 
ATOM   1737 C CG  . ASN A 1 252 ? 74.66672 38.84647 98.05284  1.000 53.81734 ? 251 ASN A CG  1 
ATOM   1738 O OD1 . ASN A 1 252 ? 73.70828 38.13694 98.37332  1.000 57.65578 ? 251 ASN A OD1 1 
ATOM   1739 N ND2 . ASN A 1 252 ? 74.67349 40.18347 98.22573  1.000 42.97581 ? 251 ASN A ND2 1 
ATOM   1740 N N   . GLY A 1 253 ? 76.14485 37.95930 93.93076  1.000 32.14025 ? 252 GLY A N   1 
ATOM   1741 C CA  . GLY A 1 253 ? 75.94623 38.70003 92.68730  1.000 32.45788 ? 252 GLY A CA  1 
ATOM   1742 C C   . GLY A 1 253 ? 76.89114 39.87867 92.54477  1.000 35.04659 ? 252 GLY A C   1 
ATOM   1743 O O   . GLY A 1 253 ? 77.39704 40.43560 93.51713  1.000 35.62822 ? 252 GLY A O   1 
ATOM   1744 N N   . THR A 1 254 ? 77.17078 40.23102 91.28976  1.000 33.53907 ? 253 THR A N   1 
ATOM   1745 C CA  . THR A 1 254 ? 78.13498 41.26797 90.93652  1.000 33.29572 ? 253 THR A CA  1 
ATOM   1746 C C   . THR A 1 254 ? 77.51723 42.18464 89.89951  1.000 36.24761 ? 253 THR A C   1 
ATOM   1747 O O   . THR A 1 254 ? 77.06338 41.70562 88.85450  1.000 37.24075 ? 253 THR A O   1 
ATOM   1748 C CB  . THR A 1 254 ? 79.41941 40.67035 90.36180  1.000 32.16598 ? 253 THR A CB  1 
ATOM   1749 O OG1 . THR A 1 254 ? 80.05559 39.85174 91.34197  1.000 36.62014 ? 253 THR A OG1 1 
ATOM   1750 C CG2 . THR A 1 254 ? 80.35936 41.76312 89.95549  1.000 28.28060 ? 253 THR A CG2 1 
ATOM   1751 N N   . LYS A 1 255 ? 77.47864 43.48976 90.19801  1.000 32.94205 ? 254 LYS A N   1 
ATOM   1752 C CA  . LYS A 1 255 ? 77.04310 44.49642 89.23578  1.000 30.80137 ? 254 LYS A CA  1 
ATOM   1753 C C   . LYS A 1 255 ? 78.22722 44.84176 88.34590  1.000 35.15089 ? 254 LYS A C   1 
ATOM   1754 O O   . LYS A 1 255 ? 79.22089 45.41134 88.80816  1.000 37.66042 ? 254 LYS A O   1 
ATOM   1755 C CB  . LYS A 1 255 ? 76.47750 45.72936 89.94111  1.000 35.57222 ? 254 LYS A CB  1 
ATOM   1756 C CG  . LYS A 1 255 ? 75.95321 46.81607 88.97878  1.000 40.96660 ? 254 LYS A CG  1 
ATOM   1757 C CD  . LYS A 1 255 ? 74.75662 46.30784 88.17369  1.000 40.86364 ? 254 LYS A CD  1 
ATOM   1758 C CE  . LYS A 1 255 ? 74.03830 47.35786 87.34437  1.000 55.46998 ? 254 LYS A CE  1 
ATOM   1759 N NZ  . LYS A 1 255 ? 72.86498 46.84825 86.56270  1.000 50.83753 ? 254 LYS A NZ  1 
ATOM   1760 N N   . VAL A 1 256 ? 78.15675 44.44716 87.08783  1.000 37.97410 ? 255 VAL A N   1 
ATOM   1761 C CA  . VAL A 1 256 ? 79.12430 44.89892 86.09997  1.000 39.41650 ? 255 VAL A CA  1 
ATOM   1762 C C   . VAL A 1 256 ? 78.52359 46.12137 85.44488  1.000 39.28748 ? 255 VAL A C   1 
ATOM   1763 O O   . VAL A 1 256 ? 77.33570 46.12643 85.10639  1.000 38.06872 ? 255 VAL A O   1 
ATOM   1764 C CB  . VAL A 1 256 ? 79.44045 43.81432 85.06330  1.000 33.47468 ? 255 VAL A CB  1 
ATOM   1765 C CG1 . VAL A 1 256 ? 80.10630 44.45944 83.85469  1.000 33.62399 ? 255 VAL A CG1 1 
ATOM   1766 C CG2 . VAL A 1 256 ? 80.34947 42.76723 85.67815  1.000 38.10230 ? 255 VAL A CG2 1 
ATOM   1767 N N   . THR A 1 257 ? 79.31103 47.17982 85.33004  1.000 41.48831 ? 256 THR A N   1 
ATOM   1768 C CA  . THR A 1 257 ? 78.82328 48.43611 84.78534  1.000 44.55253 ? 256 THR A CA  1 
ATOM   1769 C C   . THR A 1 257 ? 79.70624 48.75665 83.59383  1.000 45.88794 ? 256 THR A C   1 
ATOM   1770 O O   . THR A 1 257 ? 80.93414 48.70460 83.71313  1.000 45.02743 ? 256 THR A O   1 
ATOM   1771 C CB  . THR A 1 257 ? 78.91362 49.55523 85.81367  1.000 39.17826 ? 256 THR A CB  1 
ATOM   1772 O OG1 . THR A 1 257 ? 78.37772 49.10548 87.05893  1.000 41.82325 ? 256 THR A OG1 1 
ATOM   1773 C CG2 . THR A 1 257 ? 78.03892 50.69950 85.35736  1.000 50.92865 ? 256 THR A CG2 1 
ATOM   1774 N N   . VAL A 1 258 ? 79.10946 49.11863 82.46247  1.000 40.35665 ? 257 VAL A N   1 
ATOM   1775 C CA  . VAL A 1 258 ? 79.97735 49.35963 81.31976  1.000 43.80905 ? 257 VAL A CA  1 
ATOM   1776 C C   . VAL A 1 258 ? 80.03610 50.86114 81.05140  1.000 38.80677 ? 257 VAL A C   1 
ATOM   1777 O O   . VAL A 1 258 ? 81.00627 51.52154 81.41199  1.000 39.84377 ? 257 VAL A O   1 
ATOM   1778 C CB  . VAL A 1 258 ? 79.50720 48.60400 80.06755  1.000 48.35466 ? 257 VAL A CB  1 
ATOM   1779 C CG1 . VAL A 1 258 ? 80.53063 48.77474 78.92171  1.000 46.93079 ? 257 VAL A CG1 1 
ATOM   1780 C CG2 . VAL A 1 258 ? 79.20751 47.14461 80.38099  1.000 51.76357 ? 257 VAL A CG2 1 
ATOM   1781 N N   . GLU B 1 2   ? 48.41253 45.59889 37.12483  1.000 48.27174 ? 1   GLU B N   1 
ATOM   1782 C CA  . GLU B 1 2   ? 48.41610 44.15382 36.77602  1.000 40.60177 ? 1   GLU B CA  1 
ATOM   1783 C C   . GLU B 1 2   ? 47.07528 43.53153 37.18260  1.000 36.13704 ? 1   GLU B C   1 
ATOM   1784 O O   . GLU B 1 2   ? 46.19250 43.22756 36.35466  1.000 39.31825 ? 1   GLU B O   1 
ATOM   1785 C CB  . GLU B 1 2   ? 49.60457 43.34443 37.44681  1.000 46.81506 ? 1   GLU B CB  1 
ATOM   1786 C CG  . GLU B 1 2   ? 49.85040 42.00240 37.01492  1.000 55.71388 ? 1   GLU B CG  1 
ATOM   1787 C CD  . GLU B 1 2   ? 50.26359 41.91104 35.50589  1.000 57.64524 ? 1   GLU B CD  1 
ATOM   1788 O OE1 . GLU B 1 2   ? 50.72811 42.94212 34.92569  1.000 50.99865 ? 1   GLU B OE1 1 
ATOM   1789 O OE2 . GLU B 1 2   ? 50.18560 40.79966 34.97123  1.000 61.99722 ? 1   GLU B OE2 1 
ATOM   1790 N N   . VAL B 1 3   ? 46.93735 43.24394 38.47531  1.000 34.28056 ? 2   VAL B N   1 
ATOM   1791 C CA  . VAL B 1 3   ? 45.61878 42.85134 38.97688  1.000 36.81557 ? 2   VAL B CA  1 
ATOM   1792 C C   . VAL B 1 3   ? 44.72834 44.08332 38.87046  1.000 27.87077 ? 2   VAL B C   1 
ATOM   1793 O O   . VAL B 1 3   ? 45.03450 45.13211 39.44897  1.000 27.75994 ? 2   VAL B O   1 
ATOM   1794 C CB  . VAL B 1 3   ? 45.65328 42.33390 40.43029  1.000 33.15629 ? 2   VAL B CB  1 
ATOM   1795 C CG1 . VAL B 1 3   ? 44.24199 41.99062 40.84601  1.000 25.15717 ? 2   VAL B CG1 1 
ATOM   1796 C CG2 . VAL B 1 3   ? 46.57555 41.12124 40.56142  1.000 30.69859 ? 2   VAL B CG2 1 
ATOM   1797 N N   . GLN B 1 4   ? 43.63484 43.97723 38.11096  1.000 28.11720 ? 3   GLN B N   1 
ATOM   1798 C CA  . GLN B 1 4   ? 42.69459 45.09285 37.98651  1.000 35.51250 ? 3   GLN B CA  1 
ATOM   1799 C C   . GLN B 1 4   ? 41.24532 44.67326 38.20364  1.000 31.60598 ? 3   GLN B C   1 
ATOM   1800 O O   . GLN B 1 4   ? 40.79388 43.67299 37.64068  1.000 29.31853 ? 3   GLN B O   1 
ATOM   1801 C CB  . GLN B 1 4   ? 42.81210 45.77610 36.62082  1.000 35.05799 ? 3   GLN B CB  1 
ATOM   1802 N N   . LEU B 1 5   ? 40.51421 45.48208 38.98025  1.000 35.98984 ? 4   LEU B N   1 
ATOM   1803 C CA  . LEU B 1 5   ? 39.08596 45.32018 39.25121  1.000 36.61384 ? 4   LEU B CA  1 
ATOM   1804 C C   . LEU B 1 5   ? 38.30239 46.54846 38.80355  1.000 32.80185 ? 4   LEU B C   1 
ATOM   1805 O O   . LEU B 1 5   ? 38.67435 47.67837 39.13379  1.000 36.79472 ? 4   LEU B O   1 
ATOM   1806 C CB  . LEU B 1 5   ? 38.83030 45.07763 40.73788  1.000 29.86857 ? 4   LEU B CB  1 
ATOM   1807 C CG  . LEU B 1 5   ? 38.77935 43.62941 41.16788  1.000 30.79021 ? 4   LEU B CG  1 
ATOM   1808 C CD1 . LEU B 1 5   ? 40.11976 42.96338 40.93844  1.000 29.10534 ? 4   LEU B CD1 1 
ATOM   1809 C CD2 . LEU B 1 5   ? 38.39175 43.57456 42.63475  1.000 35.22053 ? 4   LEU B CD2 1 
ATOM   1810 N N   . VAL B 1 6   ? 37.21633 46.32870 38.06665  1.000 32.24185 ? 5   VAL B N   1 
ATOM   1811 C CA  . VAL B 1 6   ? 36.38876 47.40480 37.53399  1.000 32.39395 ? 5   VAL B CA  1 
ATOM   1812 C C   . VAL B 1 6   ? 34.94590 47.17258 37.96604  1.000 31.74867 ? 5   VAL B C   1 
ATOM   1813 O O   . VAL B 1 6   ? 34.27500 46.27003 37.45761  1.000 30.51498 ? 5   VAL B O   1 
ATOM   1814 C CB  . VAL B 1 6   ? 36.50389 47.50676 36.00436  1.000 37.73683 ? 5   VAL B CB  1 
ATOM   1815 C CG1 . VAL B 1 6   ? 35.65279 48.65251 35.45690  1.000 32.81984 ? 5   VAL B CG1 1 
ATOM   1816 C CG2 . VAL B 1 6   ? 37.96487 47.69346 35.60106  1.000 30.44746 ? 5   VAL B CG2 1 
ATOM   1817 N N   . GLU B 1 7   ? 34.44332 48.04695 38.82913  1.000 34.25264 ? 6   GLU B N   1 
ATOM   1818 C CA  . GLU B 1 7   ? 33.07554 47.98399 39.31545  1.000 32.96458 ? 6   GLU B CA  1 
ATOM   1819 C C   . GLU B 1 7   ? 32.18373 48.81396 38.40599  1.000 36.22524 ? 6   GLU B C   1 
ATOM   1820 O O   . GLU B 1 7   ? 32.57578 49.89638 37.96312  1.000 42.16305 ? 6   GLU B O   1 
ATOM   1821 C CB  . GLU B 1 7   ? 32.96628 48.53328 40.74004  1.000 32.16996 ? 6   GLU B CB  1 
ATOM   1822 C CG  . GLU B 1 7   ? 33.75767 47.83049 41.81278  1.000 32.03324 ? 6   GLU B CG  1 
ATOM   1823 C CD  . GLU B 1 7   ? 35.02980 48.55258 42.19497  1.000 34.60381 ? 6   GLU B CD  1 
ATOM   1824 O OE1 . GLU B 1 7   ? 35.22563 49.69963 41.74653  1.000 41.60670 ? 6   GLU B OE1 1 
ATOM   1825 O OE2 . GLU B 1 7   ? 35.82448 47.98547 42.97722  1.000 35.83279 ? 6   GLU B OE2 1 
ATOM   1826 N N   . SER B 1 8   ? 31.01283 48.27538 38.08029  1.000 30.40702 ? 7   SER B N   1 
ATOM   1827 C CA  . SER B 1 8   ? 30.07496 48.93711 37.18725  1.000 27.41715 ? 7   SER B CA  1 
ATOM   1828 C C   . SER B 1 8   ? 28.63699 48.78436 37.67087  1.000 30.90385 ? 7   SER B C   1 
ATOM   1829 O O   . SER B 1 8   ? 28.32121 47.93609 38.50472  1.000 31.82807 ? 7   SER B O   1 
ATOM   1830 C CB  . SER B 1 8   ? 30.17703 48.36582 35.77755  1.000 29.50393 ? 7   SER B CB  1 
ATOM   1831 O OG  . SER B 1 8   ? 29.03707 48.73803 35.03106  1.000 33.14225 ? 7   SER B OG  1 
ATOM   1832 N N   . GLY B 1 9   ? 27.75359 49.59799 37.09884  1.000 31.01741 ? 8   GLY B N   1 
ATOM   1833 C CA  . GLY B 1 9   ? 26.33224 49.46211 37.31466  1.000 24.49171 ? 8   GLY B CA  1 
ATOM   1834 C C   . GLY B 1 9   ? 25.69602 50.42789 38.27605  1.000 34.13012 ? 8   GLY B C   1 
ATOM   1835 O O   . GLY B 1 9   ? 24.46975 50.39087 38.43095  1.000 38.55136 ? 8   GLY B O   1 
ATOM   1836 N N   . GLY B 1 10  ? 26.46926 51.27072 38.94571  1.000 39.54628 ? 9   GLY B N   1 
ATOM   1837 C CA  . GLY B 1 10  ? 25.88340 52.18199 39.91280  1.000 40.56196 ? 9   GLY B CA  1 
ATOM   1838 C C   . GLY B 1 10  ? 25.13761 53.32682 39.25416  1.000 41.09291 ? 9   GLY B C   1 
ATOM   1839 O O   . GLY B 1 10  ? 25.19088 53.55441 38.04476  1.000 43.57358 ? 9   GLY B O   1 
ATOM   1840 N N   . GLY B 1 11  ? 24.42524 54.06999 40.07791  1.000 41.68880 ? 10  GLY B N   1 
ATOM   1841 C CA  . GLY B 1 11  ? 23.59370 55.13667 39.56711  1.000 37.22602 ? 10  GLY B CA  1 
ATOM   1842 C C   . GLY B 1 11  ? 22.50229 55.47957 40.55348  1.000 44.11052 ? 10  GLY B C   1 
ATOM   1843 O O   . GLY B 1 11  ? 22.37519 54.88120 41.62346  1.000 42.49950 ? 10  GLY B O   1 
ATOM   1844 N N   . LEU B 1 12  ? 21.68342 56.43396 40.13519  1.000 46.90988 ? 11  LEU B N   1 
ATOM   1845 C CA  . LEU B 1 12  ? 20.59155 56.94704 40.94988  1.000 43.22560 ? 11  LEU B CA  1 
ATOM   1846 C C   . LEU B 1 12  ? 19.39927 56.00191 40.93459  1.000 39.64522 ? 11  LEU B C   1 
ATOM   1847 O O   . LEU B 1 12  ? 18.92318 55.60409 39.86664  1.000 41.03003 ? 11  LEU B O   1 
ATOM   1848 C CB  . LEU B 1 12  ? 20.16958 58.32363 40.43671  1.000 36.05372 ? 11  LEU B CB  1 
ATOM   1849 C CG  . LEU B 1 12  ? 18.95329 58.90886 41.13588  1.000 35.13069 ? 11  LEU B CG  1 
ATOM   1850 C CD1 . LEU B 1 12  ? 19.36137 59.61415 42.41812  1.000 36.23027 ? 11  LEU B CD1 1 
ATOM   1851 C CD2 . LEU B 1 12  ? 18.20644 59.82092 40.19563  1.000 36.14540 ? 11  LEU B CD2 1 
ATOM   1852 N N   . VAL B 1 13  ? 18.92582 55.62759 42.11965  1.000 41.78132 ? 12  VAL B N   1 
ATOM   1853 C CA  . VAL B 1 13  ? 17.79715 54.71502 42.24708  1.000 43.10047 ? 12  VAL B CA  1 
ATOM   1854 C C   . VAL B 1 13  ? 16.78660 55.34556 43.17932  1.000 42.47703 ? 12  VAL B C   1 
ATOM   1855 O O   . VAL B 1 13  ? 17.14941 55.78241 44.27457  1.000 42.66577 ? 12  VAL B O   1 
ATOM   1856 C CB  . VAL B 1 13  ? 18.22264 53.35316 42.82411  1.000 38.13664 ? 12  VAL B CB  1 
ATOM   1857 C CG1 . VAL B 1 13  ? 17.01866 52.45497 42.95880  1.000 43.64257 ? 12  VAL B CG1 1 
ATOM   1858 C CG2 . VAL B 1 13  ? 19.29831 52.71698 41.98041  1.000 42.01874 ? 12  VAL B CG2 1 
ATOM   1859 N N   . GLN B 1 14  ? 15.51156 55.37397 42.75935  1.000 49.37028 ? 13  GLN B N   1 
ATOM   1860 C CA  . GLN B 1 14  ? 14.48710 55.79735 43.69951  1.000 44.54979 ? 13  GLN B CA  1 
ATOM   1861 C C   . GLN B 1 14  ? 14.19268 54.63556 44.64173  1.000 50.27115 ? 13  GLN B C   1 
ATOM   1862 O O   . GLN B 1 14  ? 14.32135 53.47654 44.24359  1.000 53.30491 ? 13  GLN B O   1 
ATOM   1863 C CB  . GLN B 1 14  ? 13.21802 56.22192 42.97077  1.000 44.28486 ? 13  GLN B CB  1 
ATOM   1864 N N   . PRO B 1 15  ? 13.74661 54.93344 45.86841  1.000 46.68779 ? 14  PRO B N   1 
ATOM   1865 C CA  . PRO B 1 15  ? 13.52126 53.91530 46.90863  1.000 49.17484 ? 14  PRO B CA  1 
ATOM   1866 C C   . PRO B 1 15  ? 13.48925 52.41935 46.56583  1.000 54.52287 ? 14  PRO B C   1 
ATOM   1867 O O   . PRO B 1 15  ? 14.44693 51.85923 46.01975  1.000 55.67903 ? 14  PRO B O   1 
ATOM   1868 C CB  . PRO B 1 15  ? 12.16695 54.36055 47.47082  1.000 47.91916 ? 14  PRO B CB  1 
ATOM   1869 C CG  . PRO B 1 15  ? 12.16338 55.89935 47.26026  1.000 48.58473 ? 14  PRO B CG  1 
ATOM   1870 C CD  . PRO B 1 15  ? 13.31707 56.25200 46.35079  1.000 46.95723 ? 14  PRO B CD  1 
ATOM   1871 N N   . GLY B 1 16  ? 12.39764 51.75110 46.93741  1.000 51.41167 ? 15  GLY B N   1 
ATOM   1872 C CA  . GLY B 1 16  ? 12.26643 50.30051 46.87192  1.000 49.52611 ? 15  GLY B CA  1 
ATOM   1873 C C   . GLY B 1 16  ? 12.71028 49.53253 45.64022  1.000 46.29304 ? 15  GLY B C   1 
ATOM   1874 O O   . GLY B 1 16  ? 12.45625 48.32960 45.54593  1.000 46.31742 ? 15  GLY B O   1 
ATOM   1875 N N   . ARG B 1 17  ? 13.39912 50.18521 44.71175  1.000 48.72979 ? 16  ARG B N   1 
ATOM   1876 C CA  . ARG B 1 17  ? 13.75423 49.57794 43.43908  1.000 46.05238 ? 16  ARG B CA  1 
ATOM   1877 C C   . ARG B 1 17  ? 14.94574 48.63161 43.61649  1.000 49.65124 ? 16  ARG B C   1 
ATOM   1878 O O   . ARG B 1 17  ? 15.47122 48.45401 44.71845  1.000 55.63092 ? 16  ARG B O   1 
ATOM   1879 C CB  . ARG B 1 17  ? 14.02337 50.66679 42.40367  1.000 49.49588 ? 16  ARG B CB  1 
ATOM   1880 N N   . SER B 1 18  ? 15.32239 47.94295 42.53869  1.000 44.01108 ? 17  SER B N   1 
ATOM   1881 C CA  . SER B 1 18  ? 16.45453 47.02331 42.53345  1.000 39.27571 ? 17  SER B CA  1 
ATOM   1882 C C   . SER B 1 18  ? 17.56857 47.48332 41.60108  1.000 46.71056 ? 17  SER B C   1 
ATOM   1883 O O   . SER B 1 18  ? 17.33445 48.20236 40.62268  1.000 53.00091 ? 17  SER B O   1 
ATOM   1884 C CB  . SER B 1 18  ? 16.03218 45.60922 42.12490  1.000 45.08099 ? 17  SER B CB  1 
ATOM   1885 O OG  . SER B 1 18  ? 15.47880 44.89752 43.21934  1.000 54.03389 ? 17  SER B OG  1 
ATOM   1886 N N   . LEU B 1 19  ? 18.79503 47.10129 41.95967  1.000 46.89496 ? 18  LEU B N   1 
ATOM   1887 C CA  . LEU B 1 19  ? 20.00737 47.39303 41.20332  1.000 45.25312 ? 18  LEU B CA  1 
ATOM   1888 C C   . LEU B 1 19  ? 20.95507 46.20308 41.29992  1.000 46.85970 ? 18  LEU B C   1 
ATOM   1889 O O   . LEU B 1 19  ? 21.05730 45.57116 42.35814  1.000 42.36912 ? 18  LEU B O   1 
ATOM   1890 C CB  . LEU B 1 19  ? 20.72846 48.63509 41.72282  1.000 44.84581 ? 18  LEU B CB  1 
ATOM   1891 C CG  . LEU B 1 19  ? 21.54344 49.40479 40.69205  1.000 42.16094 ? 18  LEU B CG  1 
ATOM   1892 C CD1 . LEU B 1 19  ? 20.66091 50.01662 39.62201  1.000 38.94262 ? 18  LEU B CD1 1 
ATOM   1893 C CD2 . LEU B 1 19  ? 22.37458 50.44969 41.40096  1.000 46.16349 ? 18  LEU B CD2 1 
ATOM   1894 N N   . ARG B 1 20  ? 21.61482 45.87063 40.18899  1.000 42.71063 ? 19  ARG B N   1 
ATOM   1895 C CA  . ARG B 1 20  ? 22.66208 44.85471 40.18434  1.000 37.55729 ? 19  ARG B CA  1 
ATOM   1896 C C   . ARG B 1 20  ? 23.98509 45.48204 39.75298  1.000 40.82224 ? 19  ARG B C   1 
ATOM   1897 O O   . ARG B 1 20  ? 24.08688 46.01942 38.64634  1.000 42.42507 ? 19  ARG B O   1 
ATOM   1898 C CB  . ARG B 1 20  ? 22.29823 43.68250 39.28236  1.000 40.18608 ? 19  ARG B CB  1 
ATOM   1899 C CG  . ARG B 1 20  ? 23.27969 42.53531 39.41639  1.000 42.72102 ? 19  ARG B CG  1 
ATOM   1900 C CD  . ARG B 1 20  ? 22.87189 41.34617 38.57206  1.000 39.19166 ? 19  ARG B CD  1 
ATOM   1901 N NE  . ARG B 1 20  ? 23.27842 41.47340 37.17779  1.000 44.24294 ? 19  ARG B NE  1 
ATOM   1902 C CZ  . ARG B 1 20  ? 23.34874 40.44163 36.33970  1.000 48.40329 ? 19  ARG B CZ  1 
ATOM   1903 N NH1 . ARG B 1 20  ? 23.72309 40.62021 35.07633  1.000 44.01073 ? 19  ARG B NH1 1 
ATOM   1904 N NH2 . ARG B 1 20  ? 23.03931 39.22301 36.77064  1.000 43.74077 ? 19  ARG B NH2 1 
ATOM   1905 N N   . LEU B 1 21  ? 24.99923 45.39649 40.60898  1.000 33.19344 ? 20  LEU B N   1 
ATOM   1906 C CA  . LEU B 1 21  ? 26.32351 45.91102 40.29373  1.000 29.09756 ? 20  LEU B CA  1 
ATOM   1907 C C   . LEU B 1 21  ? 27.19692 44.82254 39.69581  1.000 28.10987 ? 20  LEU B C   1 
ATOM   1908 O O   . LEU B 1 21  ? 27.05800 43.64521 40.02166  1.000 39.31645 ? 20  LEU B O   1 
ATOM   1909 C CB  . LEU B 1 21  ? 27.00321 46.45046 41.54893  1.000 34.80883 ? 20  LEU B CB  1 
ATOM   1910 C CG  . LEU B 1 21  ? 26.54768 47.81661 42.05056  1.000 35.13076 ? 20  LEU B CG  1 
ATOM   1911 C CD1 . LEU B 1 21  ? 26.75032 48.84451 40.98334  1.000 38.42311 ? 20  LEU B CD1 1 
ATOM   1912 C CD2 . LEU B 1 21  ? 25.11348 47.80829 42.47200  1.000 38.06299 ? 20  LEU B CD2 1 
ATOM   1913 N N   . SER B 1 22  ? 28.05887 45.20340 38.77593  1.000 30.25388 ? 21  SER B N   1 
ATOM   1914 C CA  . SER B 1 22  ? 29.02311 44.27076 38.21350  1.000 28.94843 ? 21  SER B CA  1 
ATOM   1915 C C   . SER B 1 22  ? 30.41988 44.59825 38.71010  1.000 29.34350 ? 21  SER B C   1 
ATOM   1916 O O   . SER B 1 22  ? 30.73044 45.74647 39.01876  1.000 36.38062 ? 21  SER B O   1 
ATOM   1917 C CB  . SER B 1 22  ? 29.00616 44.29640 36.68776  1.000 34.47913 ? 21  SER B CB  1 
ATOM   1918 O OG  . SER B 1 22  ? 27.76133 43.82840 36.21623  1.000 46.07661 ? 21  SER B OG  1 
ATOM   1919 N N   . CYS B 1 23  ? 31.25040 43.57009 38.80776  1.000 35.45172 ? 22  CYS B N   1 
ATOM   1920 C CA  . CYS B 1 23  ? 32.66153 43.69541 39.14272  1.000 31.19883 ? 22  CYS B CA  1 
ATOM   1921 C C   . CYS B 1 23  ? 33.45855 42.84013 38.16663  1.000 32.88037 ? 22  CYS B C   1 
ATOM   1922 O O   . CYS B 1 23  ? 33.22973 41.63153 38.07494  1.000 35.49803 ? 22  CYS B O   1 
ATOM   1923 C CB  . CYS B 1 23  ? 32.92302 43.25941 40.57802  1.000 31.90918 ? 22  CYS B CB  1 
ATOM   1924 S SG  . CYS B 1 23  ? 34.66269 43.05540 40.90435  1.000 50.84947 ? 22  CYS B SG  1 
ATOM   1925 N N   . SER B 1 24  ? 34.33045 43.47583 37.39114  1.000 28.93264 ? 23  SER B N   1 
ATOM   1926 C CA  . SER B 1 24  ? 35.12314 42.83106 36.35060  1.000 25.09040 ? 23  SER B CA  1 
ATOM   1927 C C   . SER B 1 24  ? 36.58110 42.72874 36.77310  1.000 30.47878 ? 23  SER B C   1 
ATOM   1928 O O   . SER B 1 24  ? 37.23212 43.74679 37.02335  1.000 33.22862 ? 23  SER B O   1 
ATOM   1929 C CB  . SER B 1 24  ? 35.01132 43.60823 35.04411  1.000 31.23915 ? 23  SER B CB  1 
ATOM   1930 O OG  . SER B 1 24  ? 33.65546 43.69416 34.64724  1.000 36.87979 ? 23  SER B OG  1 
ATOM   1931 N N   . ALA B 1 25  ? 37.08801 41.51225 36.87662  1.000 29.30385 ? 24  ALA B N   1 
ATOM   1932 C CA  . ALA B 1 25  ? 38.48990 41.32780 37.21152  1.000 34.22861 ? 24  ALA B CA  1 
ATOM   1933 C C   . ALA B 1 25  ? 39.32547 41.10423 35.95470  1.000 29.14679 ? 24  ALA B C   1 
ATOM   1934 O O   . ALA B 1 25  ? 38.80894 40.80397 34.87718  1.000 31.96434 ? 24  ALA B O   1 
ATOM   1935 C CB  . ALA B 1 25  ? 38.67374 40.15071 38.17586  1.000 32.84122 ? 24  ALA B CB  1 
ATOM   1936 N N   . SER B 1 26  ? 40.63517 41.26560 36.11342  1.000 25.07376 ? 25  SER B N   1 
ATOM   1937 C CA  . SER B 1 26  ? 41.62963 40.92663 35.10357  1.000 29.18598 ? 25  SER B CA  1 
ATOM   1938 C C   . SER B 1 26  ? 42.98958 40.97601 35.78373  1.000 26.44631 ? 25  SER B C   1 
ATOM   1939 O O   . SER B 1 26  ? 43.22812 41.84595 36.61806  1.000 32.22687 ? 25  SER B O   1 
ATOM   1940 C CB  . SER B 1 26  ? 41.58082 41.87484 33.88899  1.000 37.73106 ? 25  SER B CB  1 
ATOM   1941 O OG  . SER B 1 26  ? 41.65836 43.24822 34.26166  1.000 31.83146 ? 25  SER B OG  1 
ATOM   1942 N N   . GLY B 1 27  ? 43.87683 40.05902 35.41976  1.000 29.21738 ? 26  GLY B N   1 
ATOM   1943 C CA  . GLY B 1 27  ? 45.23026 40.06309 35.94240  1.000 30.43550 ? 26  GLY B CA  1 
ATOM   1944 C C   . GLY B 1 27  ? 45.58149 38.92849 36.88167  1.000 30.62248 ? 26  GLY B C   1 
ATOM   1945 O O   . GLY B 1 27  ? 46.73318 38.86180 37.32253  1.000 34.81980 ? 26  GLY B O   1 
ATOM   1946 N N   . PHE B 1 28  ? 44.63825 38.04682 37.21448  1.000 26.77665 ? 27  PHE B N   1 
ATOM   1947 C CA  . PHE B 1 28  ? 44.88722 36.87640 38.05289  1.000 25.35997 ? 27  PHE B CA  1 
ATOM   1948 C C   . PHE B 1 28  ? 43.90384 35.77024 37.65581  1.000 34.53806 ? 27  PHE B C   1 
ATOM   1949 O O   . PHE B 1 28  ? 42.95341 35.99121 36.89665  1.000 34.72417 ? 27  PHE B O   1 
ATOM   1950 C CB  . PHE B 1 28  ? 44.75261 37.21938 39.54110  1.000 23.09950 ? 27  PHE B CB  1 
ATOM   1951 C CG  . PHE B 1 28  ? 43.42423 37.78676 39.89883  1.000 23.62518 ? 27  PHE B CG  1 
ATOM   1952 C CD1 . PHE B 1 28  ? 42.46258 37.00206 40.48669  1.000 25.32973 ? 27  PHE B CD1 1 
ATOM   1953 C CD2 . PHE B 1 28  ? 43.11573 39.10061 39.60484  1.000 28.92087 ? 27  PHE B CD2 1 
ATOM   1954 C CE1 . PHE B 1 28  ? 41.21599 37.51717 40.79635  1.000 24.62388 ? 27  PHE B CE1 1 
ATOM   1955 C CE2 . PHE B 1 28  ? 41.87710 39.62294 39.90912  1.000 30.14505 ? 27  PHE B CE2 1 
ATOM   1956 C CZ  . PHE B 1 28  ? 40.92462 38.81976 40.51187  1.000 27.96111 ? 27  PHE B CZ  1 
ATOM   1957 N N   . THR B 1 29  ? 44.10130 34.57493 38.20031  1.000 31.74847 ? 28  THR B N   1 
ATOM   1958 C CA  . THR B 1 29  ? 43.21448 33.47643 37.82706  1.000 25.07675 ? 28  THR B CA  1 
ATOM   1959 C C   . THR B 1 29  ? 41.95287 33.63146 38.65803  1.000 25.33967 ? 28  THR B C   1 
ATOM   1960 O O   . THR B 1 29  ? 41.87498 33.18671 39.80093  1.000 30.73370 ? 28  THR B O   1 
ATOM   1961 C CB  . THR B 1 29  ? 43.88086 32.12551 38.03970  1.000 30.63048 ? 28  THR B CB  1 
ATOM   1962 O OG1 . THR B 1 29  ? 44.91374 31.94893 37.05933  1.000 38.97771 ? 28  THR B OG1 1 
ATOM   1963 C CG2 . THR B 1 29  ? 42.86236 31.01080 37.88319  1.000 29.67184 ? 28  THR B CG2 1 
ATOM   1964 N N   . PHE B 1 30  ? 40.96374 34.30995 38.07028  1.000 24.95556 ? 29  PHE B N   1 
ATOM   1965 C CA  . PHE B 1 30  ? 39.80845 34.80335 38.81914  1.000 28.00007 ? 29  PHE B CA  1 
ATOM   1966 C C   . PHE B 1 30  ? 39.22489 33.73357 39.74107  1.000 29.38966 ? 29  PHE B C   1 
ATOM   1967 O O   . PHE B 1 30  ? 38.94379 34.00189 40.91526  1.000 26.50273 ? 29  PHE B O   1 
ATOM   1968 C CB  . PHE B 1 30  ? 38.74869 35.31420 37.82283  1.000 28.39387 ? 29  PHE B CB  1 
ATOM   1969 C CG  . PHE B 1 30  ? 37.43193 35.74119 38.44838  1.000 24.41985 ? 29  PHE B CG  1 
ATOM   1970 C CD1 . PHE B 1 30  ? 37.31512 36.93264 39.11007  1.000 26.46960 ? 29  PHE B CD1 1 
ATOM   1971 C CD2 . PHE B 1 30  ? 36.30949 34.96153 38.32391  1.000 31.15405 ? 29  PHE B CD2 1 
ATOM   1972 C CE1 . PHE B 1 30  ? 36.11564 37.31578 39.65988  1.000 31.19435 ? 29  PHE B CE1 1 
ATOM   1973 C CE2 . PHE B 1 30  ? 35.10281 35.35233 38.86344  1.000 32.66072 ? 29  PHE B CE2 1 
ATOM   1974 C CZ  . PHE B 1 30  ? 35.00718 36.51858 39.53596  1.000 29.45112 ? 29  PHE B CZ  1 
ATOM   1975 N N   . GLY B 1 31  ? 39.07810 32.50307 39.24140  1.000 25.49475 ? 30  GLY B N   1 
ATOM   1976 C CA  . GLY B 1 31  ? 38.35047 31.49181 39.98376  1.000 22.57929 ? 30  GLY B CA  1 
ATOM   1977 C C   . GLY B 1 31  ? 39.01848 31.07907 41.27122  1.000 22.16522 ? 30  GLY B C   1 
ATOM   1978 O O   . GLY B 1 31  ? 38.35100 30.54745 42.16118  1.000 24.18115 ? 30  GLY B O   1 
ATOM   1979 N N   . ASP B 1 32  ? 40.29653 31.38707 41.42516  1.000 23.19098 ? 31  ASP B N   1 
ATOM   1980 C CA  . ASP B 1 32  ? 41.10284 30.87491 42.52055  1.000 23.83085 ? 31  ASP B CA  1 
ATOM   1981 C C   . ASP B 1 32  ? 41.05638 31.75968 43.75679  1.000 28.52676 ? 31  ASP B C   1 
ATOM   1982 O O   . ASP B 1 32  ? 41.81022 31.51230 44.70804  1.000 23.77140 ? 31  ASP B O   1 
ATOM   1983 C CB  . ASP B 1 32  ? 42.55227 30.71471 42.05353  1.000 23.93008 ? 31  ASP B CB  1 
ATOM   1984 C CG  . ASP B 1 32  ? 42.73151 29.54146 41.09758  1.000 28.25770 ? 31  ASP B CG  1 
ATOM   1985 O OD1 . ASP B 1 32  ? 41.72274 28.87698 40.77065  1.000 27.67551 ? 31  ASP B OD1 1 
ATOM   1986 O OD2 . ASP B 1 32  ? 43.88104 29.27512 40.68795  1.000 29.52042 ? 31  ASP B OD2 1 
ATOM   1987 N N   . TYR B 1 33  ? 40.19946 32.78899 43.75516  1.000 27.61059 ? 32  TYR B N   1 
ATOM   1988 C CA  . TYR B 1 33  ? 40.20049 33.82941 44.77453  1.000 23.62953 ? 32  TYR B CA  1 
ATOM   1989 C C   . TYR B 1 33  ? 38.79122 34.13374 45.25865  1.000 29.02553 ? 32  TYR B C   1 
ATOM   1990 O O   . TYR B 1 33  ? 37.86108 34.26250 44.45149  1.000 28.01216 ? 32  TYR B O   1 
ATOM   1991 C CB  . TYR B 1 33  ? 40.83650 35.10879 44.24081  1.000 25.52758 ? 32  TYR B CB  1 
ATOM   1992 C CG  . TYR B 1 33  ? 42.30703 34.99026 44.00845  1.000 23.64616 ? 32  TYR B CG  1 
ATOM   1993 C CD1 . TYR B 1 33  ? 42.79556 34.58889 42.77498  1.000 25.57503 ? 32  TYR B CD1 1 
ATOM   1994 C CD2 . TYR B 1 33  ? 43.21341 35.27722 45.01954  1.000 23.21258 ? 32  TYR B CD2 1 
ATOM   1995 C CE1 . TYR B 1 33  ? 44.15328 34.47987 42.54962  1.000 26.20411 ? 32  TYR B CE1 1 
ATOM   1996 C CE2 . TYR B 1 33  ? 44.57099 35.18587 44.79938  1.000 22.57797 ? 32  TYR B CE2 1 
ATOM   1997 C CZ  . TYR B 1 33  ? 45.03148 34.78676 43.56376  1.000 22.48436 ? 32  TYR B CZ  1 
ATOM   1998 O OH  . TYR B 1 33  ? 46.37920 34.67682 43.33166  1.000 30.09058 ? 32  TYR B OH  1 
ATOM   1999 N N   . ALA B 1 34  ? 38.63497 34.22633 46.57790  1.000 27.33361 ? 33  ALA B N   1 
ATOM   2000 C CA  . ALA B 1 34  ? 37.42403 34.80298 47.13041  1.000 25.47382 ? 33  ALA B CA  1 
ATOM   2001 C C   . ALA B 1 34  ? 37.28603 36.24926 46.66176  1.000 31.04396 ? 33  ALA B C   1 
ATOM   2002 O O   . ALA B 1 34  ? 38.27095 36.92939 46.35825  1.000 23.49874 ? 33  ALA B O   1 
ATOM   2003 C CB  . ALA B 1 34  ? 37.45327 34.73538 48.65528  1.000 24.49765 ? 33  ALA B CB  1 
ATOM   2004 N N   . MET B 1 35  ? 36.04733 36.72014 46.61088  1.000 32.51563 ? 34  MET B N   1 
ATOM   2005 C CA  . MET B 1 35  ? 35.74729 38.08334 46.21739  1.000 27.71820 ? 34  MET B CA  1 
ATOM   2006 C C   . MET B 1 35  ? 34.76846 38.66148 47.22182  1.000 31.61891 ? 34  MET B C   1 
ATOM   2007 O O   . MET B 1 35  ? 33.84110 37.97930 47.66338  1.000 34.89987 ? 34  MET B O   1 
ATOM   2008 C CB  . MET B 1 35  ? 35.17028 38.13775 44.81940  1.000 25.50870 ? 34  MET B CB  1 
ATOM   2009 C CG  . MET B 1 35  ? 36.13385 37.67618 43.73748  1.000 32.39557 ? 34  MET B CG  1 
ATOM   2010 S SD  . MET B 1 35  ? 37.54644 38.76857 43.44698  1.000 37.40643 ? 34  MET B SD  1 
ATOM   2011 C CE  . MET B 1 35  ? 36.72928 40.17397 42.72203  1.000 25.96350 ? 34  MET B CE  1 
ATOM   2012 N N   . SER B 1 36  ? 34.99337 39.91031 47.59347  1.000 29.51202 ? 35  SER B N   1 
ATOM   2013 C CA  . SER B 1 36  ? 34.22598 40.56479 48.63267  1.000 27.23673 ? 35  SER B CA  1 
ATOM   2014 C C   . SER B 1 36  ? 33.75502 41.92447 48.14514  1.000 29.71491 ? 35  SER B C   1 
ATOM   2015 O O   . SER B 1 36  ? 34.43808 42.60177 47.37160  1.000 31.26164 ? 35  SER B O   1 
ATOM   2016 C CB  . SER B 1 36  ? 35.05223 40.72278 49.89880  1.000 30.72402 ? 35  SER B CB  1 
ATOM   2017 O OG  . SER B 1 36  ? 34.21019 40.91002 51.01766  1.000 36.06127 ? 35  SER B OG  1 
ATOM   2018 N N   . TRP B 1 37  ? 32.56420 42.30077 48.58538  1.000 33.67913 ? 36  TRP B N   1 
ATOM   2019 C CA  . TRP B 1 37  ? 31.98505 43.60227 48.29721  1.000 27.46106 ? 36  TRP B CA  1 
ATOM   2020 C C   . TRP B 1 37  ? 32.09204 44.50166 49.52468  1.000 35.02395 ? 36  TRP B C   1 
ATOM   2021 O O   . TRP B 1 37  ? 31.83039 44.06349 50.65113  1.000 32.32290 ? 36  TRP B O   1 
ATOM   2022 C CB  . TRP B 1 37  ? 30.53066 43.44944 47.87486  1.000 26.88719 ? 36  TRP B CB  1 
ATOM   2023 C CG  . TRP B 1 37  ? 30.40585 43.04115 46.43439  1.000 36.73980 ? 36  TRP B CG  1 
ATOM   2024 C CD1 . TRP B 1 37  ? 30.19474 41.76846 45.94584  1.000 32.32840 ? 36  TRP B CD1 1 
ATOM   2025 C CD2 . TRP B 1 37  ? 30.48140 43.90270 45.28804  1.000 29.58051 ? 36  TRP B CD2 1 
ATOM   2026 N NE1 . TRP B 1 37  ? 30.12994 41.79820 44.56950  1.000 36.11067 ? 36  TRP B NE1 1 
ATOM   2027 C CE2 . TRP B 1 37  ? 30.30559 43.09171 44.14161  1.000 35.28580 ? 36  TRP B CE2 1 
ATOM   2028 C CE3 . TRP B 1 37  ? 30.69090 45.27577 45.11764  1.000 31.75984 ? 36  TRP B CE3 1 
ATOM   2029 C CZ2 . TRP B 1 37  ? 30.32973 43.61528 42.84646  1.000 31.08509 ? 36  TRP B CZ2 1 
ATOM   2030 C CZ3 . TRP B 1 37  ? 30.71417 45.79827 43.82091  1.000 31.82963 ? 36  TRP B CZ3 1 
ATOM   2031 C CH2 . TRP B 1 37  ? 30.53371 44.96969 42.71092  1.000 34.68645 ? 36  TRP B CH2 1 
ATOM   2032 N N   . PHE B 1 38  ? 32.54128 45.73512 49.31424  1.000 33.56484 ? 37  PHE B N   1 
ATOM   2033 C CA  . PHE B 1 38  ? 32.58954 46.72913 50.37064  1.000 29.10076 ? 37  PHE B CA  1 
ATOM   2034 C C   . PHE B 1 38  ? 31.86836 47.97530 49.89034  1.000 27.60012 ? 37  PHE B C   1 
ATOM   2035 O O   . PHE B 1 38  ? 31.75979 48.23067 48.69147  1.000 25.85164 ? 37  PHE B O   1 
ATOM   2036 C CB  . PHE B 1 38  ? 34.03275 47.09346 50.75983  1.000 30.24897 ? 37  PHE B CB  1 
ATOM   2037 C CG  . PHE B 1 38  ? 34.82180 45.95311 51.37484  1.000 31.02969 ? 37  PHE B CG  1 
ATOM   2038 C CD1 . PHE B 1 38  ? 35.29556 44.91995 50.59999  1.000 32.09591 ? 37  PHE B CD1 1 
ATOM   2039 C CD2 . PHE B 1 38  ? 35.10998 45.93824 52.72684  1.000 31.09827 ? 37  PHE B CD2 1 
ATOM   2040 C CE1 . PHE B 1 38  ? 36.02400 43.88721 51.15521  1.000 34.68554 ? 37  PHE B CE1 1 
ATOM   2041 C CE2 . PHE B 1 38  ? 35.83754 44.91059 53.27431  1.000 34.04727 ? 37  PHE B CE2 1 
ATOM   2042 C CZ  . PHE B 1 38  ? 36.29258 43.88490 52.48877  1.000 32.62910 ? 37  PHE B CZ  1 
ATOM   2043 N N   . ARG B 1 39  ? 31.40574 48.77497 50.84009  1.000 32.94147 ? 38  ARG B N   1 
ATOM   2044 C CA  . ARG B 1 39  ? 30.74200 50.02984 50.52256  1.000 29.96204 ? 38  ARG B CA  1 
ATOM   2045 C C   . ARG B 1 39  ? 31.20630 51.12835 51.46856  1.000 27.41771 ? 38  ARG B C   1 
ATOM   2046 O O   . ARG B 1 39  ? 31.45550 50.88295 52.65166  1.000 31.12041 ? 38  ARG B O   1 
ATOM   2047 C CB  . ARG B 1 39  ? 29.22570 49.88583 50.56132  1.000 33.37612 ? 38  ARG B CB  1 
ATOM   2048 C CG  . ARG B 1 39  ? 28.64367 49.56532 51.90550  1.000 26.61916 ? 38  ARG B CG  1 
ATOM   2049 C CD  . ARG B 1 39  ? 27.16943 49.78277 51.82227  1.000 26.45014 ? 38  ARG B CD  1 
ATOM   2050 N NE  . ARG B 1 39  ? 26.47290 49.33982 53.01448  1.000 29.56434 ? 38  ARG B NE  1 
ATOM   2051 C CZ  . ARG B 1 39  ? 25.18631 49.02879 53.03577  1.000 29.15520 ? 38  ARG B CZ  1 
ATOM   2052 N NH1 . ARG B 1 39  ? 24.47155 49.13669 51.92375  1.000 31.69481 ? 38  ARG B NH1 1 
ATOM   2053 N NH2 . ARG B 1 39  ? 24.61574 48.63278 54.16633  1.000 30.96584 ? 38  ARG B NH2 1 
ATOM   2054 N N   . LEU B 1 40  ? 31.37649 52.32246 50.91596  1.000 31.48014 ? 39  LEU B N   1 
ATOM   2055 C CA  . LEU B 1 40  ? 31.68856 53.53935 51.66039  1.000 31.12042 ? 39  LEU B CA  1 
ATOM   2056 C C   . LEU B 1 40  ? 30.47127 54.44763 51.60091  1.000 30.68268 ? 39  LEU B C   1 
ATOM   2057 O O   . LEU B 1 40  ? 30.08137 54.89360 50.51973  1.000 29.22875 ? 39  LEU B O   1 
ATOM   2058 C CB  . LEU B 1 40  ? 32.91460 54.24267 51.07226  1.000 34.79315 ? 39  LEU B CB  1 
ATOM   2059 C CG  . LEU B 1 40  ? 33.18349 55.71776 51.40102  1.000 35.19696 ? 39  LEU B CG  1 
ATOM   2060 C CD1 . LEU B 1 40  ? 33.54861 55.87332 52.85823  1.000 35.37656 ? 39  LEU B CD1 1 
ATOM   2061 C CD2 . LEU B 1 40  ? 34.28457 56.29541 50.51899  1.000 28.31298 ? 39  LEU B CD2 1 
ATOM   2062 N N   . ALA B 1 41  ? 29.89472 54.73922 52.75582  1.000 38.03898 ? 40  ALA B N   1 
ATOM   2063 C CA  . ALA B 1 41  ? 28.64273 55.46924 52.88517  1.000 36.64031 ? 40  ALA B CA  1 
ATOM   2064 C C   . ALA B 1 41  ? 28.87355 56.84102 53.53597  1.000 37.67517 ? 40  ALA B C   1 
ATOM   2065 O O   . ALA B 1 41  ? 29.83770 57.02477 54.28647  1.000 35.84655 ? 40  ALA B O   1 
ATOM   2066 C CB  . ALA B 1 41  ? 27.64134 54.65126 53.71287  1.000 28.58825 ? 40  ALA B CB  1 
ATOM   2067 N N   . PRO B 1 42  ? 28.02995 57.83185 53.24340  1.000 34.43089 ? 41  PRO B N   1 
ATOM   2068 C CA  . PRO B 1 42  ? 28.30385 59.19721 53.71575  1.000 36.64638 ? 41  PRO B CA  1 
ATOM   2069 C C   . PRO B 1 42  ? 28.37934 59.27532 55.23049  1.000 37.78802 ? 41  PRO B C   1 
ATOM   2070 O O   . PRO B 1 42  ? 27.64644 58.58858 55.94447  1.000 38.78199 ? 41  PRO B O   1 
ATOM   2071 C CB  . PRO B 1 42  ? 27.10604 59.99946 53.19681  1.000 36.29480 ? 41  PRO B CB  1 
ATOM   2072 C CG  . PRO B 1 42  ? 26.37982 59.09017 52.24824  1.000 37.52754 ? 41  PRO B CG  1 
ATOM   2073 C CD  . PRO B 1 42  ? 26.68977 57.71065 52.65021  1.000 31.97295 ? 41  PRO B CD  1 
ATOM   2074 N N   . GLY B 1 43  ? 29.28468 60.10697 55.72836  1.000 33.40350 ? 42  GLY B N   1 
ATOM   2075 C CA  . GLY B 1 43  ? 29.36401 60.24066 57.16806  1.000 38.47253 ? 42  GLY B CA  1 
ATOM   2076 C C   . GLY B 1 43  ? 29.93161 59.02867 57.87310  1.000 51.19966 ? 42  GLY B C   1 
ATOM   2077 O O   . GLY B 1 43  ? 30.85271 59.15002 58.68988  1.000 72.72214 ? 42  GLY B O   1 
ATOM   2078 N N   . LYS B 1 44  ? 29.36225 57.85699 57.60294  1.000 46.10315 ? 43  LYS B N   1 
ATOM   2079 C CA  . LYS B 1 44  ? 29.90196 56.61909 58.14253  1.000 53.18395 ? 43  LYS B CA  1 
ATOM   2080 C C   . LYS B 1 44  ? 31.28450 56.34146 57.52970  1.000 53.67396 ? 43  LYS B C   1 
ATOM   2081 O O   . LYS B 1 44  ? 31.79247 57.09102 56.68692  1.000 53.63363 ? 43  LYS B O   1 
ATOM   2082 C CB  . LYS B 1 44  ? 28.94271 55.46023 57.85866  1.000 49.60579 ? 43  LYS B CB  1 
ATOM   2083 C CG  . LYS B 1 44  ? 27.48800 55.86452 57.63053  1.000 46.20530 ? 43  LYS B CG  1 
ATOM   2084 C CD  . LYS B 1 44  ? 26.77311 56.21924 58.91923  1.000 55.39611 ? 43  LYS B CD  1 
ATOM   2085 C CE  . LYS B 1 44  ? 25.34860 56.70994 58.65083  1.000 63.75631 ? 43  LYS B CE  1 
ATOM   2086 N NZ  . LYS B 1 44  ? 24.42746 56.54292 59.82706  1.000 56.31992 ? 43  LYS B NZ  1 
ATOM   2087 N N   . GLY B 1 45  ? 31.91399 55.26106 57.96837  1.000 51.61403 ? 44  GLY B N   1 
ATOM   2088 C CA  . GLY B 1 45  ? 33.16844 54.82868 57.37608  1.000 40.05691 ? 44  GLY B CA  1 
ATOM   2089 C C   . GLY B 1 45  ? 32.96225 53.75772 56.32327  1.000 41.57680 ? 44  GLY B C   1 
ATOM   2090 O O   . GLY B 1 45  ? 32.03949 53.82649 55.50311  1.000 42.24825 ? 44  GLY B O   1 
ATOM   2091 N N   . LEU B 1 46  ? 33.81064 52.74094 56.36063  1.000 32.49576 ? 45  LEU B N   1 
ATOM   2092 C CA  . LEU B 1 46  ? 33.69328 51.60362 55.46303  1.000 32.80579 ? 45  LEU B CA  1 
ATOM   2093 C C   . LEU B 1 46  ? 32.85200 50.49070 56.06806  1.000 34.32146 ? 45  LEU B C   1 
ATOM   2094 O O   . LEU B 1 46  ? 32.79826 50.31745 57.29096  1.000 35.31791 ? 45  LEU B O   1 
ATOM   2095 C CB  . LEU B 1 46  ? 35.06981 51.05093 55.13640  1.000 25.20842 ? 45  LEU B CB  1 
ATOM   2096 C CG  . LEU B 1 46  ? 35.82148 51.80797 54.08259  1.000 23.01712 ? 45  LEU B CG  1 
ATOM   2097 C CD1 . LEU B 1 46  ? 37.29084 51.72799 54.38857  1.000 20.08784 ? 45  LEU B CD1 1 
ATOM   2098 C CD2 . LEU B 1 46  ? 35.48211 51.18074 52.73370  1.000 34.37109 ? 45  LEU B CD2 1 
ATOM   2099 N N   . GLU B 1 47  ? 32.20569 49.72223 55.19626  1.000 31.25926 ? 46  GLU B N   1 
ATOM   2100 C CA  . GLU B 1 47  ? 31.43950 48.57120 55.64076  1.000 35.76057 ? 46  GLU B CA  1 
ATOM   2101 C C   . GLU B 1 47  ? 31.68066 47.38443 54.71920  1.000 36.68021 ? 46  GLU B C   1 
ATOM   2102 O O   . GLU B 1 47  ? 31.79592 47.53675 53.49815  1.000 33.98315 ? 46  GLU B O   1 
ATOM   2103 C CB  . GLU B 1 47  ? 29.95946 48.90962 55.72033  1.000 32.45669 ? 46  GLU B CB  1 
ATOM   2104 C CG  . GLU B 1 47  ? 29.70256 49.84597 56.85158  1.000 38.90008 ? 46  GLU B CG  1 
ATOM   2105 C CD  . GLU B 1 47  ? 28.33649 50.45041 56.81154  1.000 49.03713 ? 46  GLU B CD  1 
ATOM   2106 O OE1 . GLU B 1 47  ? 27.65629 50.27681 55.77128  1.000 43.80111 ? 46  GLU B OE1 1 
ATOM   2107 O OE2 . GLU B 1 47  ? 27.97397 51.13940 57.80040  1.000 56.35478 ? 46  GLU B OE2 1 
ATOM   2108 N N   . TRP B 1 48  ? 31.77520 46.20527 55.32448  1.000 34.36414 ? 47  TRP B N   1 
ATOM   2109 C CA  . TRP B 1 48  ? 31.74502 44.95439 54.58254  1.000 39.80568 ? 47  TRP B CA  1 
ATOM   2110 C C   . TRP B 1 48  ? 30.31001 44.66071 54.15409  1.000 36.75606 ? 47  TRP B C   1 
ATOM   2111 O O   . TRP B 1 48  ? 29.36947 44.88294 54.91812  1.000 37.43979 ? 47  TRP B O   1 
ATOM   2112 C CB  . TRP B 1 48  ? 32.30606 43.82100 55.44861  1.000 37.27525 ? 47  TRP B CB  1 
ATOM   2113 C CG  . TRP B 1 48  ? 32.27470 42.50735 54.79206  1.000 33.08584 ? 47  TRP B CG  1 
ATOM   2114 C CD1 . TRP B 1 48  ? 33.01713 42.11262 53.72667  1.000 34.63831 ? 47  TRP B CD1 1 
ATOM   2115 C CD2 . TRP B 1 48  ? 31.43692 41.40179 55.13725  1.000 34.13425 ? 47  TRP B CD2 1 
ATOM   2116 N NE1 . TRP B 1 48  ? 32.69926 40.81862 53.38388  1.000 36.98431 ? 47  TRP B NE1 1 
ATOM   2117 C CE2 . TRP B 1 48  ? 31.72766 40.36080 54.23594  1.000 33.25147 ? 47  TRP B CE2 1 
ATOM   2118 C CE3 . TRP B 1 48  ? 30.47097 41.19119 56.11795  1.000 32.61746 ? 47  TRP B CE3 1 
ATOM   2119 C CZ2 . TRP B 1 48  ? 31.09392 39.12585 54.29269  1.000 31.08537 ? 47  TRP B CZ2 1 
ATOM   2120 C CZ3 . TRP B 1 48  ? 29.83781 39.95811 56.16712  1.000 38.81156 ? 47  TRP B CZ3 1 
ATOM   2121 C CH2 . TRP B 1 48  ? 30.14896 38.94619 55.25880  1.000 32.93809 ? 47  TRP B CH2 1 
ATOM   2122 N N   . VAL B 1 49  ? 30.12880 44.21677 52.91273  1.000 28.36026 ? 48  VAL B N   1 
ATOM   2123 C CA  . VAL B 1 49  ? 28.77767 43.91728 52.45722  1.000 25.90753 ? 48  VAL B CA  1 
ATOM   2124 C C   . VAL B 1 49  ? 28.54389 42.41455 52.42092  1.000 33.76866 ? 48  VAL B C   1 
ATOM   2125 O O   . VAL B 1 49  ? 27.58132 41.90481 53.00411  1.000 37.51471 ? 48  VAL B O   1 
ATOM   2126 C CB  . VAL B 1 49  ? 28.50051 44.54824 51.08902  1.000 30.85803 ? 48  VAL B CB  1 
ATOM   2127 C CG1 . VAL B 1 49  ? 27.06655 44.23612 50.63679  1.000 26.49467 ? 48  VAL B CG1 1 
ATOM   2128 C CG2 . VAL B 1 49  ? 28.76676 46.05342 51.14277  1.000 29.61970 ? 48  VAL B CG2 1 
ATOM   2129 N N   . GLY B 1 50  ? 29.38913 41.69732 51.69948  1.000 37.65744 ? 49  GLY B N   1 
ATOM   2130 C CA  . GLY B 1 50  ? 29.24072 40.25700 51.63660  1.000 33.24091 ? 49  GLY B CA  1 
ATOM   2131 C C   . GLY B 1 50  ? 30.46180 39.62825 51.00202  1.000 34.80891 ? 49  GLY B C   1 
ATOM   2132 O O   . GLY B 1 50  ? 31.34990 40.31872 50.49146  1.000 29.89652 ? 49  GLY B O   1 
ATOM   2133 N N   . LEU B 1 51  ? 30.46384 38.29313 50.97124  1.000 34.92342 ? 50  LEU B N   1 
ATOM   2134 C CA  . LEU B 1 51  ? 31.65206 37.57621 50.54389  1.000 29.30771 ? 50  LEU B CA  1 
ATOM   2135 C C   . LEU B 1 51  ? 31.23332 36.37172 49.72020  1.000 26.40326 ? 50  LEU B C   1 
ATOM   2136 O O   . LEU B 1 51  ? 30.33084 35.63767 50.12294  1.000 29.77395 ? 50  LEU B O   1 
ATOM   2137 C CB  . LEU B 1 51  ? 32.45477 37.12545 51.75549  1.000 28.02391 ? 50  LEU B CB  1 
ATOM   2138 C CG  . LEU B 1 51  ? 33.90606 36.75577 51.46800  1.000 31.75714 ? 50  LEU B CG  1 
ATOM   2139 C CD1 . LEU B 1 51  ? 34.66034 36.87445 52.74343  1.000 32.33370 ? 50  LEU B CD1 1 
ATOM   2140 C CD2 . LEU B 1 51  ? 34.13705 35.41113 50.85278  1.000 34.11604 ? 50  LEU B CD2 1 
ATOM   2141 N N   . ILE B 1 52  ? 31.91015 36.15310 48.59402  1.000 27.55787 ? 51  ILE B N   1 
ATOM   2142 C CA  . ILE B 1 52  ? 31.75430 34.94952 47.77687  1.000 29.23393 ? 51  ILE B CA  1 
ATOM   2143 C C   . ILE B 1 52  ? 33.10373 34.24850 47.68211  1.000 29.17457 ? 51  ILE B C   1 
ATOM   2144 O O   . ILE B 1 52  ? 34.13148 34.88995 47.42204  1.000 23.71479 ? 51  ILE B O   1 
ATOM   2145 C CB  . ILE B 1 52  ? 31.21266 35.26993 46.36831  1.000 29.59297 ? 51  ILE B CB  1 
ATOM   2146 C CG1 . ILE B 1 52  ? 31.01884 34.00198 45.53127  1.000 32.12150 ? 51  ILE B CG1 1 
ATOM   2147 C CG2 . ILE B 1 52  ? 32.13768 36.19982 45.60860  1.000 30.41989 ? 51  ILE B CG2 1 
ATOM   2148 C CD1 . ILE B 1 52  ? 29.91503 33.11320 45.96612  1.000 35.10694 ? 51  ILE B CD1 1 
ATOM   2149 N N   . LYS B 1 53  ? 33.10530 32.93950 47.93482  1.000 28.55569 ? 52  LYS B N   1 
ATOM   2150 C CA  . LYS B 1 53  ? 34.35148 32.18922 47.95047  1.000 25.83713 ? 52  LYS B CA  1 
ATOM   2151 C C   . LYS B 1 53  ? 34.66465 31.58081 46.58284  1.000 27.30688 ? 52  LYS B C   1 
ATOM   2152 O O   . LYS B 1 53  ? 33.83319 31.54960 45.67659  1.000 29.31401 ? 52  LYS B O   1 
ATOM   2153 C CB  . LYS B 1 53  ? 34.29876 31.10087 49.02051  1.000 31.35178 ? 52  LYS B CB  1 
ATOM   2154 C CG  . LYS B 1 53  ? 34.21871 31.64210 50.43706  1.000 32.41841 ? 52  LYS B CG  1 
ATOM   2155 C CD  . LYS B 1 53  ? 34.00057 30.52693 51.44794  1.000 40.44419 ? 52  LYS B CD  1 
ATOM   2156 C CE  . LYS B 1 53  ? 32.79219 30.77104 52.32700  1.000 36.42419 ? 52  LYS B CE  1 
ATOM   2157 N NZ  . LYS B 1 53  ? 32.75681 29.83704 53.46213  1.000 34.42075 ? 52  LYS B NZ  1 
ATOM   2158 N N   . SER B 1 54  ? 35.87580 31.04077 46.46308  1.000 31.62118 ? 53  SER B N   1 
ATOM   2159 C CA  . SER B 1 54  ? 36.25067 30.26547 45.28603  1.000 30.43874 ? 53  SER B CA  1 
ATOM   2160 C C   . SER B 1 54  ? 35.36352 29.02910 45.23581  1.000 29.97917 ? 53  SER B C   1 
ATOM   2161 O O   . SER B 1 54  ? 34.99322 28.48268 46.27479  1.000 32.36854 ? 53  SER B O   1 
ATOM   2162 C CB  . SER B 1 54  ? 37.73736 29.88159 45.37509  1.000 29.64797 ? 53  SER B CB  1 
ATOM   2163 O OG  . SER B 1 54  ? 38.11132 28.86711 44.46314  1.000 26.21107 ? 53  SER B OG  1 
ATOM   2164 N N   . ARG B 1 55  ? 34.99210 28.59474 44.02319  1.000 36.40316 ? 54  ARG B N   1 
ATOM   2165 C CA  . ARG B 1 55  ? 34.11569 27.42641 43.94706  1.000 38.35841 ? 54  ARG B CA  1 
ATOM   2166 C C   . ARG B 1 55  ? 34.82178 26.17131 44.47747  1.000 35.75435 ? 54  ARG B C   1 
ATOM   2167 O O   . ARG B 1 55  ? 34.14098 25.24703 44.94377  1.000 33.00586 ? 54  ARG B O   1 
ATOM   2168 C CB  . ARG B 1 55  ? 33.56508 27.17611 42.52203  1.000 34.17224 ? 54  ARG B CB  1 
ATOM   2169 C CG  . ARG B 1 55  ? 32.79445 28.38363 41.88973  1.000 40.02361 ? 54  ARG B CG  1 
ATOM   2170 C CD  . ARG B 1 55  ? 32.07655 27.96676 40.60229  1.000 46.92011 ? 54  ARG B CD  1 
ATOM   2171 N NE  . ARG B 1 55  ? 31.62725 29.01440 39.66954  1.000 54.47517 ? 54  ARG B NE  1 
ATOM   2172 C CZ  . ARG B 1 55  ? 30.47768 29.67835 39.75356  1.000 51.49130 ? 54  ARG B CZ  1 
ATOM   2173 N NH1 . ARG B 1 55  ? 29.69077 29.47826 40.81398  1.000 50.69273 ? 54  ARG B NH1 1 
ATOM   2174 N NH2 . ARG B 1 55  ? 30.14055 30.58813 38.82431  1.000 47.39605 ? 54  ARG B NH2 1 
ATOM   2175 N N   . ALA B 1 56  ? 36.16660 26.15034 44.49792  1.000 33.48823 ? 55  ALA B N   1 
ATOM   2176 C CA  . ALA B 1 56  ? 36.93400 25.03876 45.07391  1.000 34.64609 ? 55  ALA B CA  1 
ATOM   2177 C C   . ALA B 1 56  ? 36.98901 24.97312 46.60091  1.000 32.55820 ? 55  ALA B C   1 
ATOM   2178 O O   . ALA B 1 56  ? 37.83452 24.26142 47.14570  1.000 45.80034 ? 55  ALA B O   1 
ATOM   2179 C CB  . ALA B 1 56  ? 38.38938 25.05369 44.56745  1.000 29.40113 ? 55  ALA B CB  1 
ATOM   2180 N N   . ILE B 1 57  ? 36.14892 25.71976 47.30939  1.000 38.50596 ? 56  ILE B N   1 
ATOM   2181 C CA  . ILE B 1 57  ? 36.10690 25.66794 48.77273  1.000 41.83576 ? 56  ILE B CA  1 
ATOM   2182 C C   . ILE B 1 57  ? 34.65149 25.89169 49.16909  1.000 46.57916 ? 56  ILE B C   1 
ATOM   2183 O O   . ILE B 1 57  ? 34.07474 25.14451 49.96810  1.000 48.34430 ? 56  ILE B O   1 
ATOM   2184 C CB  . ILE B 1 57  ? 37.05824 26.69768 49.42272  1.000 22.26557 ? 56  ILE B CB  1 
ATOM   2185 N N   . ASP B 1 58  ? 34.07201 26.94781 48.60202  1.000 47.26508 ? 57  ASP B N   1 
ATOM   2186 C CA  . ASP B 1 58  ? 32.67125 27.35230 48.70250  1.000 53.15480 ? 57  ASP B CA  1 
ATOM   2187 C C   . ASP B 1 58  ? 32.04743 27.21083 50.08811  1.000 57.73176 ? 57  ASP B C   1 
ATOM   2188 O O   . ASP B 1 58  ? 32.70299 27.43940 51.11342  1.000 57.24781 ? 57  ASP B O   1 
ATOM   2189 C CB  . ASP B 1 58  ? 31.83297 26.58473 47.67122  1.000 51.85876 ? 57  ASP B CB  1 
ATOM   2190 C CG  . ASP B 1 58  ? 30.59642 27.36787 47.22650  1.000 50.44451 ? 57  ASP B CG  1 
ATOM   2191 O OD1 . ASP B 1 58  ? 30.78710 28.46758 46.67484  1.000 47.26827 ? 57  ASP B OD1 1 
ATOM   2192 O OD2 . ASP B 1 58  ? 29.44966 26.89660 47.40710  1.000 53.82212 ? 57  ASP B OD2 1 
ATOM   2193 N N   . GLY B 1 59  ? 30.78596 26.80705 50.11355  1.000 52.77549 ? 58  GLY B N   1 
ATOM   2194 C CA  . GLY B 1 59  ? 29.99027 26.82665 51.30821  1.000 54.78318 ? 58  GLY B CA  1 
ATOM   2195 C C   . GLY B 1 59  ? 29.03351 27.99305 51.41635  1.000 53.43117 ? 58  GLY B C   1 
ATOM   2196 O O   . GLY B 1 59  ? 28.78892 28.45320 52.53700  1.000 52.48626 ? 58  GLY B O   1 
ATOM   2197 N N   . THR B 1 60  ? 28.49138 28.49556 50.27547  1.000 47.40385 ? 59  THR B N   1 
ATOM   2198 C CA  . THR B 1 60  ? 27.46012 29.53735 50.20001  1.000 46.83646 ? 59  THR B CA  1 
ATOM   2199 C C   . THR B 1 60  ? 27.98237 30.95572 50.44977  1.000 51.41717 ? 59  THR B C   1 
ATOM   2200 O O   . THR B 1 60  ? 28.76894 31.17909 51.37885  1.000 52.45583 ? 59  THR B O   1 
ATOM   2201 C CB  . THR B 1 60  ? 26.31070 29.23286 51.16877  1.000 40.11361 ? 59  THR B CB  1 
ATOM   2202 N N   . PRO B 1 61  ? 27.60154 31.93161 49.62763  1.000 39.39501 ? 60  PRO B N   1 
ATOM   2203 C CA  . PRO B 1 61  ? 28.10337 33.28865 49.82568  1.000 30.36067 ? 60  PRO B CA  1 
ATOM   2204 C C   . PRO B 1 61  ? 27.57591 33.85455 51.13278  1.000 39.30806 ? 60  PRO B C   1 
ATOM   2205 O O   . PRO B 1 61  ? 26.46578 33.54183 51.57019  1.000 38.82577 ? 60  PRO B O   1 
ATOM   2206 C CB  . PRO B 1 61  ? 27.53883 34.05551 48.62853  1.000 32.99349 ? 60  PRO B CB  1 
ATOM   2207 C CG  . PRO B 1 61  ? 26.85713 33.04324 47.77284  1.000 39.10341 ? 60  PRO B CG  1 
ATOM   2208 C CD  . PRO B 1 61  ? 26.51021 31.90588 48.65036  1.000 42.25066 ? 60  PRO B CD  1 
ATOM   2209 N N   . GLN B 1 62  ? 28.38296 34.71787 51.74105  1.000 36.53986 ? 61  GLN B N   1 
ATOM   2210 C CA  . GLN B 1 62  ? 28.09790 35.33569 53.02990  1.000 37.15504 ? 61  GLN B CA  1 
ATOM   2211 C C   . GLN B 1 62  ? 27.73478 36.80140 52.87832  1.000 40.58467 ? 61  GLN B C   1 
ATOM   2212 O O   . GLN B 1 62  ? 28.26983 37.49164 52.00989  1.000 43.08394 ? 61  GLN B O   1 
ATOM   2213 C CB  . GLN B 1 62  ? 29.30158 35.27107 53.93940  1.000 35.60018 ? 61  GLN B CB  1 
ATOM   2214 C CG  . GLN B 1 62  ? 29.56910 33.96649 54.57754  1.000 34.15815 ? 61  GLN B CG  1 
ATOM   2215 C CD  . GLN B 1 62  ? 30.63404 34.14978 55.61779  1.000 40.82807 ? 61  GLN B CD  1 
ATOM   2216 O OE1 . GLN B 1 62  ? 30.33794 34.44783 56.78001  1.000 46.99468 ? 61  GLN B OE1 1 
ATOM   2217 N NE2 . GLN B 1 62  ? 31.89438 34.05227 55.19598  1.000 37.13117 ? 61  GLN B NE2 1 
ATOM   2218 N N   . TYR B 1 63  ? 26.79531 37.25791 53.69063  1.000 38.08188 ? 62  TYR B N   1 
ATOM   2219 C CA  . TYR B 1 63  ? 26.39032 38.65511 53.72332  1.000 36.27880 ? 62  TYR B CA  1 
ATOM   2220 C C   . TYR B 1 63  ? 26.57914 39.20648 55.13554  1.000 36.08618 ? 62  TYR B C   1 
ATOM   2221 O O   . TYR B 1 63  ? 27.06085 38.51716 56.03065  1.000 45.31943 ? 62  TYR B O   1 
ATOM   2222 C CB  . TYR B 1 63  ? 24.95238 38.76738 53.22528  1.000 36.81382 ? 62  TYR B CB  1 
ATOM   2223 C CG  . TYR B 1 63  ? 24.73278 37.88259 52.01103  1.000 40.63919 ? 62  TYR B CG  1 
ATOM   2224 C CD1 . TYR B 1 63  ? 25.34486 38.17494 50.80044  1.000 38.88107 ? 62  TYR B CD1 1 
ATOM   2225 C CD2 . TYR B 1 63  ? 23.95525 36.73799 52.08562  1.000 42.14951 ? 62  TYR B CD2 1 
ATOM   2226 C CE1 . TYR B 1 63  ? 25.16234 37.37773 49.69160  1.000 40.97072 ? 62  TYR B CE1 1 
ATOM   2227 C CE2 . TYR B 1 63  ? 23.76839 35.93083 50.98024  1.000 44.93723 ? 62  TYR B CE2 1 
ATOM   2228 C CZ  . TYR B 1 63  ? 24.37614 36.25650 49.78384  1.000 46.18599 ? 62  TYR B CZ  1 
ATOM   2229 O OH  . TYR B 1 63  ? 24.19523 35.46287 48.67264  1.000 52.93804 ? 62  TYR B OH  1 
ATOM   2230 N N   . ALA B 1 64  ? 26.24166 40.47326 55.32650  1.000 36.56718 ? 63  ALA B N   1 
ATOM   2231 C CA  . ALA B 1 64  ? 26.32844 41.12883 56.62701  1.000 36.96273 ? 63  ALA B CA  1 
ATOM   2232 C C   . ALA B 1 64  ? 24.94024 41.57269 57.07498  1.000 42.54192 ? 63  ALA B C   1 
ATOM   2233 O O   . ALA B 1 64  ? 24.09457 41.89772 56.24584  1.000 42.28896 ? 63  ALA B O   1 
ATOM   2234 C CB  . ALA B 1 64  ? 27.28155 42.32021 56.59634  1.000 37.43681 ? 63  ALA B CB  1 
ATOM   2235 N N   . ALA B 1 65  ? 24.71686 41.59545 58.39373  1.000 49.00867 ? 64  ALA B N   1 
ATOM   2236 C CA  . ALA B 1 65  ? 23.43702 41.94105 59.02106  1.000 40.56011 ? 64  ALA B CA  1 
ATOM   2237 C C   . ALA B 1 65  ? 22.52654 42.92031 58.26035  1.000 49.88001 ? 64  ALA B C   1 
ATOM   2238 O O   . ALA B 1 65  ? 21.39528 42.54766 57.92024  1.000 55.44178 ? 64  ALA B O   1 
ATOM   2239 C CB  . ALA B 1 65  ? 23.71917 42.50888 60.40912  1.000 33.55870 ? 64  ALA B CB  1 
ATOM   2240 N N   . SER B 1 66  ? 22.99121 44.15494 57.98147  1.000 40.31689 ? 65  SER B N   1 
ATOM   2241 C CA  . SER B 1 66  ? 22.18153 45.12820 57.23142  1.000 47.48231 ? 65  SER B CA  1 
ATOM   2242 C C   . SER B 1 66  ? 21.70426 44.54563 55.90970  1.000 47.82351 ? 65  SER B C   1 
ATOM   2243 O O   . SER B 1 66  ? 20.62412 44.88612 55.40994  1.000 48.29245 ? 65  SER B O   1 
ATOM   2244 C CB  . SER B 1 66  ? 22.97745 46.41276 56.97700  1.000 53.12705 ? 65  SER B CB  1 
ATOM   2245 N N   . VAL B 1 67  ? 22.53993 43.70922 55.31209  1.000 48.06890 ? 66  VAL B N   1 
ATOM   2246 C CA  . VAL B 1 67  ? 22.33921 43.03512 54.04264  1.000 41.01182 ? 66  VAL B CA  1 
ATOM   2247 C C   . VAL B 1 67  ? 21.82639 41.63438 54.37793  1.000 47.44131 ? 66  VAL B C   1 
ATOM   2248 O O   . VAL B 1 67  ? 22.58968 40.66009 54.42306  1.000 51.68466 ? 66  VAL B O   1 
ATOM   2249 C CB  . VAL B 1 67  ? 23.67219 43.06016 53.26793  1.000 34.38393 ? 66  VAL B CB  1 
ATOM   2250 C CG1 . VAL B 1 67  ? 23.76399 42.01863 52.22005  1.000 29.62838 ? 66  VAL B CG1 1 
ATOM   2251 C CG2 . VAL B 1 67  ? 23.83178 44.42429 52.64291  1.000 38.52146 ? 66  VAL B CG2 1 
ATOM   2252 N N   . LYS B 1 68  ? 20.55417 41.54849 54.75572  1.000 50.30648 ? 67  LYS B N   1 
ATOM   2253 C CA  . LYS B 1 68  ? 19.98449 40.28427 55.21041  1.000 56.60824 ? 67  LYS B CA  1 
ATOM   2254 C C   . LYS B 1 68  ? 19.74969 39.31459 54.05308  1.000 60.97321 ? 67  LYS B C   1 
ATOM   2255 O O   . LYS B 1 68  ? 20.69345 38.80430 53.43239  1.000 61.97003 ? 67  LYS B O   1 
ATOM   2256 C CB  . LYS B 1 68  ? 18.67489 40.52463 55.96744  1.000 53.14571 ? 67  LYS B CB  1 
ATOM   2257 N N   . GLY B 1 69  ? 18.47367 39.05388 53.77295  1.000 55.37881 ? 68  GLY B N   1 
ATOM   2258 C CA  . GLY B 1 69  ? 17.95421 38.25352 52.68270  1.000 49.32401 ? 68  GLY B CA  1 
ATOM   2259 C C   . GLY B 1 69  ? 17.72650 38.99345 51.38101  1.000 64.18945 ? 68  GLY B C   1 
ATOM   2260 O O   . GLY B 1 69  ? 17.21858 38.39187 50.42757  1.000 64.32516 ? 68  GLY B O   1 
ATOM   2261 N N   . ARG B 1 70  ? 18.10182 40.28041 51.30115  1.000 60.17820 ? 69  ARG B N   1 
ATOM   2262 C CA  . ARG B 1 70  ? 17.79112 41.10959 50.14417  1.000 47.13803 ? 69  ARG B CA  1 
ATOM   2263 C C   . ARG B 1 70  ? 18.96920 41.43038 49.23708  1.000 42.82686 ? 69  ARG B C   1 
ATOM   2264 O O   . ARG B 1 70  ? 18.73585 41.82471 48.08950  1.000 43.64121 ? 69  ARG B O   1 
ATOM   2265 C CB  . ARG B 1 70  ? 17.14075 42.42490 50.59658  1.000 54.05813 ? 69  ARG B CB  1 
ATOM   2266 C CG  . ARG B 1 70  ? 17.95151 43.23271 51.59446  1.000 53.04367 ? 69  ARG B CG  1 
ATOM   2267 C CD  . ARG B 1 70  ? 17.13473 44.35461 52.21211  1.000 41.85090 ? 69  ARG B CD  1 
ATOM   2268 N NE  . ARG B 1 70  ? 18.00105 45.30009 52.90310  1.000 45.62886 ? 69  ARG B NE  1 
ATOM   2269 C CZ  . ARG B 1 70  ? 18.62223 46.30218 52.29008  1.000 52.37734 ? 69  ARG B CZ  1 
ATOM   2270 N NH1 . ARG B 1 70  ? 19.40480 47.12982 52.97084  1.000 42.38650 ? 69  ARG B NH1 1 
ATOM   2271 N NH2 . ARG B 1 70  ? 18.45311 46.47606 50.98247  1.000 53.48884 ? 69  ARG B NH2 1 
ATOM   2272 N N   . PHE B 1 71  ? 20.20923 41.30397 49.69928  1.000 40.35100 ? 70  PHE B N   1 
ATOM   2273 C CA  . PHE B 1 71  ? 21.32630 41.36708 48.76640  1.000 45.83105 ? 70  PHE B CA  1 
ATOM   2274 C C   . PHE B 1 71  ? 21.75009 39.94505 48.44998  1.000 44.35160 ? 70  PHE B C   1 
ATOM   2275 O O   . PHE B 1 71  ? 21.61919 39.04283 49.28299  1.000 42.37476 ? 70  PHE B O   1 
ATOM   2276 C CB  . PHE B 1 71  ? 22.54806 42.10857 49.29713  1.000 43.93053 ? 70  PHE B CB  1 
ATOM   2277 C CG  . PHE B 1 71  ? 22.42104 43.59139 49.32478  1.000 38.48153 ? 70  PHE B CG  1 
ATOM   2278 C CD1 . PHE B 1 71  ? 21.19087 44.20357 49.43896  1.000 41.96482 ? 70  PHE B CD1 1 
ATOM   2279 C CD2 . PHE B 1 71  ? 23.55522 44.37799 49.25474  1.000 38.63181 ? 70  PHE B CD2 1 
ATOM   2280 C CE1 . PHE B 1 71  ? 21.09321 45.57888 49.47225  1.000 43.69424 ? 70  PHE B CE1 1 
ATOM   2281 C CE2 . PHE B 1 71  ? 23.46769 45.75756 49.29030  1.000 38.17027 ? 70  PHE B CE2 1 
ATOM   2282 C CZ  . PHE B 1 71  ? 22.23846 46.35782 49.39228  1.000 39.50739 ? 70  PHE B CZ  1 
ATOM   2283 N N   . THR B 1 72  ? 22.30467 39.75469 47.25732  1.000 42.59216 ? 71  THR B N   1 
ATOM   2284 C CA  . THR B 1 72  ? 22.60361 38.40044 46.81797  1.000 43.48549 ? 71  THR B CA  1 
ATOM   2285 C C   . THR B 1 72  ? 23.87745 38.47356 45.99648  1.000 40.03319 ? 71  THR B C   1 
ATOM   2286 O O   . THR B 1 72  ? 23.91198 39.19848 45.00398  1.000 39.12555 ? 71  THR B O   1 
ATOM   2287 C CB  . THR B 1 72  ? 21.44167 37.85961 45.97282  1.000 47.67554 ? 71  THR B CB  1 
ATOM   2288 O OG1 . THR B 1 72  ? 20.20369 38.07676 46.66651  1.000 48.11270 ? 71  THR B OG1 1 
ATOM   2289 C CG2 . THR B 1 72  ? 21.58326 36.35232 45.80305  1.000 59.82940 ? 71  THR B CG2 1 
ATOM   2290 N N   . ILE B 1 73  ? 24.91954 37.74574 46.39598  1.000 44.48362 ? 72  ILE B N   1 
ATOM   2291 C CA  . ILE B 1 73  ? 26.22175 37.81832 45.73664  1.000 40.13941 ? 72  ILE B CA  1 
ATOM   2292 C C   . ILE B 1 73  ? 26.45683 36.55604 44.91282  1.000 41.67250 ? 72  ILE B C   1 
ATOM   2293 O O   . ILE B 1 73  ? 26.10525 35.44978 45.33551  1.000 41.33926 ? 72  ILE B O   1 
ATOM   2294 C CB  . ILE B 1 73  ? 27.35779 38.01204 46.75799  1.000 41.30973 ? 72  ILE B CB  1 
ATOM   2295 C CG1 . ILE B 1 73  ? 27.33216 39.41085 47.33707  1.000 37.40306 ? 72  ILE B CG1 1 
ATOM   2296 C CG2 . ILE B 1 73  ? 28.71618 37.85834 46.10280  1.000 37.80687 ? 72  ILE B CG2 1 
ATOM   2297 C CD1 . ILE B 1 73  ? 28.29412 39.54389 48.47495  1.000 27.19636 ? 72  ILE B CD1 1 
ATOM   2298 N N   . SER B 1 74  ? 27.08154 36.72568 43.74762  1.000 39.43504 ? 73  SER B N   1 
ATOM   2299 C CA  . SER B 1 74  ? 27.29585 35.63522 42.81100  1.000 37.30235 ? 73  SER B CA  1 
ATOM   2300 C C   . SER B 1 74  ? 28.47893 35.96228 41.90457  1.000 37.96284 ? 73  SER B C   1 
ATOM   2301 O O   . SER B 1 74  ? 28.94984 37.10247 41.84637  1.000 30.91379 ? 73  SER B O   1 
ATOM   2302 C CB  . SER B 1 74  ? 26.03647 35.37411 41.98949  1.000 37.28473 ? 73  SER B CB  1 
ATOM   2303 O OG  . SER B 1 74  ? 25.78825 36.46009 41.12259  1.000 46.59454 ? 73  SER B OG  1 
ATOM   2304 N N   . ARG B 1 75  ? 28.97922 34.92771 41.22916  1.000 35.05208 ? 74  ARG B N   1 
ATOM   2305 C CA  . ARG B 1 75  ? 30.14023 35.04018 40.35558  1.000 36.80682 ? 74  ARG B CA  1 
ATOM   2306 C C   . ARG B 1 75  ? 29.90536 34.25499 39.06628  1.000 39.84530 ? 74  ARG B C   1 
ATOM   2307 O O   . ARG B 1 75  ? 29.06086 33.35483 38.99503  1.000 33.57238 ? 74  ARG B O   1 
ATOM   2308 C CB  . ARG B 1 75  ? 31.42922 34.57122 41.04632  1.000 36.93858 ? 74  ARG B CB  1 
ATOM   2309 C CG  . ARG B 1 75  ? 31.36712 33.18575 41.67511  1.000 32.03029 ? 74  ARG B CG  1 
ATOM   2310 C CD  . ARG B 1 75  ? 32.54590 32.98044 42.62502  1.000 32.22918 ? 74  ARG B CD  1 
ATOM   2311 N NE  . ARG B 1 75  ? 33.84482 33.21485 41.98253  1.000 31.56066 ? 74  ARG B NE  1 
ATOM   2312 C CZ  . ARG B 1 75  ? 34.99310 33.32163 42.64633  1.000 26.64328 ? 74  ARG B CZ  1 
ATOM   2313 N NH1 . ARG B 1 75  ? 35.01777 33.20957 43.96506  1.000 27.16167 ? 74  ARG B NH1 1 
ATOM   2314 N NH2 . ARG B 1 75  ? 36.11861 33.53257 41.99629  1.000 25.82517 ? 74  ARG B NH2 1 
ATOM   2315 N N   . ASP B 1 76  ? 30.66681 34.62153 38.03526  1.000 37.46840 ? 75  ASP B N   1 
ATOM   2316 C CA  . ASP B 1 76  ? 30.71347 33.89194 36.77279  1.000 31.62120 ? 75  ASP B CA  1 
ATOM   2317 C C   . ASP B 1 76  ? 32.18242 33.76029 36.39514  1.000 37.43683 ? 75  ASP B C   1 
ATOM   2318 O O   . ASP B 1 76  ? 32.76407 34.67649 35.81391  1.000 45.47121 ? 75  ASP B O   1 
ATOM   2319 C CB  . ASP B 1 76  ? 29.89923 34.60013 35.70240  1.000 39.44058 ? 75  ASP B CB  1 
ATOM   2320 C CG  . ASP B 1 76  ? 29.99928 33.92649 34.34207  1.000 44.80781 ? 75  ASP B CG  1 
ATOM   2321 O OD1 . ASP B 1 76  ? 30.24282 34.63103 33.32821  1.000 44.18566 ? 75  ASP B OD1 1 
ATOM   2322 O OD2 . ASP B 1 76  ? 29.83241 32.68853 34.29267  1.000 48.11611 ? 75  ASP B OD2 1 
ATOM   2323 N N   . ASP B 1 77  ? 32.78451 32.62304 36.75621  1.000 45.34419 ? 76  ASP B N   1 
ATOM   2324 C CA  . ASP B 1 77  ? 34.20249 32.39150 36.49928  1.000 37.54792 ? 76  ASP B CA  1 
ATOM   2325 C C   . ASP B 1 77  ? 34.51322 32.28991 35.01847  1.000 40.32123 ? 76  ASP B C   1 
ATOM   2326 O O   . ASP B 1 77  ? 35.67020 32.48468 34.62888  1.000 47.99267 ? 76  ASP B O   1 
ATOM   2327 C CB  . ASP B 1 77  ? 34.68093 31.13319 37.21514  1.000 35.14693 ? 76  ASP B CB  1 
ATOM   2328 C CG  . ASP B 1 77  ? 34.39977 31.16934 38.71373  1.000 41.97047 ? 76  ASP B CG  1 
ATOM   2329 O OD1 . ASP B 1 77  ? 34.91322 32.06763 39.42668  1.000 32.79361 ? 76  ASP B OD1 1 
ATOM   2330 O OD2 . ASP B 1 77  ? 33.64292 30.28968 39.17595  1.000 42.97457 ? 76  ASP B OD2 1 
ATOM   2331 N N   . SER B 1 78  ? 33.52810 31.94490 34.19040  1.000 35.46764 ? 77  SER B N   1 
ATOM   2332 C CA  . SER B 1 78  ? 33.79283 31.82639 32.76012  1.000 40.81786 ? 77  SER B CA  1 
ATOM   2333 C C   . SER B 1 78  ? 34.07217 33.18264 32.12753  1.000 45.19698 ? 77  SER B C   1 
ATOM   2334 O O   . SER B 1 78  ? 34.73224 33.25760 31.08213  1.000 44.51787 ? 77  SER B O   1 
ATOM   2335 C CB  . SER B 1 78  ? 32.61765 31.14949 32.05926  1.000 47.10350 ? 77  SER B CB  1 
ATOM   2336 O OG  . SER B 1 78  ? 31.38534 31.69173 32.49403  1.000 47.18909 ? 77  SER B OG  1 
ATOM   2337 N N   . ASN B 1 79  ? 33.58045 34.26059 32.74310  1.000 48.55091 ? 78  ASN B N   1 
ATOM   2338 C CA  . ASN B 1 79  ? 33.82462 35.61369 32.26349  1.000 43.62332 ? 78  ASN B CA  1 
ATOM   2339 C C   . ASN B 1 79  ? 34.51673 36.46992 33.31169  1.000 44.12410 ? 78  ASN B C   1 
ATOM   2340 O O   . ASN B 1 79  ? 34.59576 37.69353 33.14536  1.000 47.19118 ? 78  ASN B O   1 
ATOM   2341 C CB  . ASN B 1 79  ? 32.51330 36.28254 31.84792  1.000 41.75841 ? 78  ASN B CB  1 
ATOM   2342 C CG  . ASN B 1 79  ? 31.90054 35.65063 30.63051  1.000 41.90164 ? 78  ASN B CG  1 
ATOM   2343 O OD1 . ASN B 1 79  ? 32.60828 35.23873 29.69348  1.000 36.25434 ? 78  ASN B OD1 1 
ATOM   2344 N ND2 . ASN B 1 79  ? 30.56984 35.57073 30.62451  1.000 42.00570 ? 78  ASN B ND2 1 
ATOM   2345 N N   . SER B 1 80  ? 35.03410 35.85463 34.36993  1.000 40.08189 ? 79  SER B N   1 
ATOM   2346 C CA  . SER B 1 80  ? 35.90459 36.50899 35.33583  1.000 34.91630 ? 79  SER B CA  1 
ATOM   2347 C C   . SER B 1 80  ? 35.24439 37.76334 35.92163  1.000 38.22253 ? 79  SER B C   1 
ATOM   2348 O O   . SER B 1 80  ? 35.78211 38.86941 35.89282  1.000 43.74906 ? 79  SER B O   1 
ATOM   2349 C CB  . SER B 1 80  ? 37.25146 36.80056 34.67073  1.000 35.65186 ? 79  SER B CB  1 
ATOM   2350 O OG  . SER B 1 80  ? 38.19352 37.31482 35.58826  1.000 48.89358 ? 79  SER B OG  1 
ATOM   2351 N N   . ILE B 1 81  ? 34.06137 37.55190 36.49791  1.000 39.99379 ? 80  ILE B N   1 
ATOM   2352 C CA  . ILE B 1 81  ? 33.13949 38.61355 36.90353  1.000 34.27425 ? 80  ILE B CA  1 
ATOM   2353 C C   . ILE B 1 81  ? 32.31146 38.28410 38.15287  1.000 36.12992 ? 80  ILE B C   1 
ATOM   2354 O O   . ILE B 1 81  ? 31.61651 37.26062 38.21024  1.000 35.44649 ? 80  ILE B O   1 
ATOM   2355 C CB  . ILE B 1 81  ? 32.22427 38.93727 35.71091  1.000 34.36934 ? 80  ILE B CB  1 
ATOM   2356 C CG1 . ILE B 1 81  ? 31.18964 40.00442 36.05669  1.000 31.37106 ? 80  ILE B CG1 1 
ATOM   2357 C CG2 . ILE B 1 81  ? 31.64818 37.67952 35.10539  1.000 44.12871 ? 80  ILE B CG2 1 
ATOM   2358 C CD1 . ILE B 1 81  ? 30.43153 40.47234 34.83934  1.000 32.00498 ? 80  ILE B CD1 1 
ATOM   2359 N N   . ALA B 1 82  ? 32.38899 39.13950 39.17457  1.000 37.03805 ? 81  ALA B N   1 
ATOM   2360 C CA  . ALA B 1 82  ? 31.53412 39.03055 40.35517  1.000 35.99145 ? 81  ALA B CA  1 
ATOM   2361 C C   . ALA B 1 82  ? 30.40557 40.05754 40.29380  1.000 29.97252 ? 81  ALA B C   1 
ATOM   2362 O O   . ALA B 1 82  ? 30.52156 41.09464 39.65126  1.000 31.99478 ? 81  ALA B O   1 
ATOM   2363 C CB  . ALA B 1 82  ? 32.34267 39.20872 41.64777  1.000 34.17722 ? 81  ALA B CB  1 
ATOM   2364 N N   . TYR B 1 83  ? 29.32285 39.76622 41.01061  1.000 36.28380 ? 82  TYR B N   1 
ATOM   2365 C CA  . TYR B 1 83  ? 28.07306 40.51239 40.94392  1.000 31.84401 ? 82  TYR B CA  1 
ATOM   2366 C C   . TYR B 1 83  ? 27.54736 40.83570 42.33711  1.000 36.75410 ? 82  TYR B C   1 
ATOM   2367 O O   . TYR B 1 83  ? 27.74138 40.07044 43.28429  1.000 41.40285 ? 82  TYR B O   1 
ATOM   2368 C CB  . TYR B 1 83  ? 26.99351 39.69751 40.23260  1.000 35.17621 ? 82  TYR B CB  1 
ATOM   2369 C CG  . TYR B 1 83  ? 27.10909 39.61844 38.73962  1.000 34.01105 ? 82  TYR B CG  1 
ATOM   2370 C CD1 . TYR B 1 83  ? 27.49198 38.44909 38.12432  1.000 35.19954 ? 82  TYR B CD1 1 
ATOM   2371 C CD2 . TYR B 1 83  ? 26.79504 40.70066 37.94386  1.000 38.36568 ? 82  TYR B CD2 1 
ATOM   2372 C CE1 . TYR B 1 83  ? 27.58834 38.36766 36.75060  1.000 38.10811 ? 82  TYR B CE1 1 
ATOM   2373 C CE2 . TYR B 1 83  ? 26.88447 40.62765 36.56970  1.000 36.14224 ? 82  TYR B CE2 1 
ATOM   2374 C CZ  . TYR B 1 83  ? 27.27862 39.45837 35.97735  1.000 37.83424 ? 82  TYR B CZ  1 
ATOM   2375 O OH  . TYR B 1 83  ? 27.37257 39.37538 34.60243  1.000 46.05656 ? 82  TYR B OH  1 
ATOM   2376 N N   . LEU B 1 84  ? 26.84876 41.96162 42.45992  1.000 33.56318 ? 83  LEU B N   1 
ATOM   2377 C CA  . LEU B 1 84  ? 26.05317 42.23062 43.65198  1.000 37.59408 ? 83  LEU B CA  1 
ATOM   2378 C C   . LEU B 1 84  ? 24.63369 42.58972 43.24172  1.000 35.65174 ? 83  LEU B C   1 
ATOM   2379 O O   . LEU B 1 84  ? 24.41980 43.59420 42.55758  1.000 43.41236 ? 83  LEU B O   1 
ATOM   2380 C CB  . LEU B 1 84  ? 26.66311 43.34968 44.49263  1.000 37.55389 ? 83  LEU B CB  1 
ATOM   2381 C CG  . LEU B 1 84  ? 25.84135 43.73761 45.72575  1.000 32.48902 ? 83  LEU B CG  1 
ATOM   2382 C CD1 . LEU B 1 84  ? 25.58014 42.53218 46.59915  1.000 30.32457 ? 83  LEU B CD1 1 
ATOM   2383 C CD2 . LEU B 1 84  ? 26.52374 44.85965 46.50974  1.000 32.23835 ? 83  LEU B CD2 1 
ATOM   2384 N N   . GLN B 1 85  ? 23.66952 41.78754 43.66987  1.000 31.48544 ? 84  GLN B N   1 
ATOM   2385 C CA  . GLN B 1 85  ? 22.26187 42.06684 43.43429  1.000 31.99771 ? 84  GLN B CA  1 
ATOM   2386 C C   . GLN B 1 85  ? 21.64958 42.59880 44.71667  1.000 39.33897 ? 84  GLN B C   1 
ATOM   2387 O O   . GLN B 1 85  ? 21.76692 41.96941 45.77464  1.000 38.32064 ? 84  GLN B O   1 
ATOM   2388 C CB  . GLN B 1 85  ? 21.49523 40.83489 42.97258  1.000 36.58639 ? 84  GLN B CB  1 
ATOM   2389 C CG  . GLN B 1 85  ? 20.00266 41.04432 43.01181  1.000 39.61434 ? 84  GLN B CG  1 
ATOM   2390 C CD  . GLN B 1 85  ? 19.44138 41.43940 41.66911  1.000 41.70388 ? 84  GLN B CD  1 
ATOM   2391 O OE1 . GLN B 1 85  ? 19.84047 40.90240 40.64168  1.000 48.04321 ? 84  GLN B OE1 1 
ATOM   2392 N NE2 . GLN B 1 85  ? 18.52878 42.40108 41.66563  1.000 39.39869 ? 84  GLN B NE2 1 
ATOM   2393 N N   . MET B 1 86  ? 21.03940 43.77724 44.62141  1.000 44.44590 ? 85  MET B N   1 
ATOM   2394 C CA  . MET B 1 86  ? 20.36730 44.43146 45.73015  1.000 40.66855 ? 85  MET B CA  1 
ATOM   2395 C C   . MET B 1 86  ? 18.89013 44.61471 45.42069  1.000 36.52350 ? 85  MET B C   1 
ATOM   2396 O O   . MET B 1 86  ? 18.53809 45.11964 44.35275  1.000 34.96305 ? 85  MET B O   1 
ATOM   2397 C CB  . MET B 1 86  ? 20.99762 45.78247 46.01772  1.000 39.67555 ? 85  MET B CB  1 
ATOM   2398 C CG  . MET B 1 86  ? 22.50489 45.83084 46.00628  1.000 33.72129 ? 85  MET B CG  1 
ATOM   2399 S SD  . MET B 1 86  ? 22.82546 47.58543 46.09962  1.000 39.19958 ? 85  MET B SD  1 
ATOM   2400 C CE  . MET B 1 86  ? 24.51066 47.77573 45.63345  1.000 35.03136 ? 85  MET B CE  1 
ATOM   2401 N N   . ASN B 1 87  ? 18.03552 44.24194 46.36486  1.000 37.57635 ? 86  ASN B N   1 
ATOM   2402 C CA  . ASN B 1 87  ? 16.59754 44.41834 46.23195  1.000 41.00957 ? 86  ASN B CA  1 
ATOM   2403 C C   . ASN B 1 87  ? 16.08016 45.25971 47.39334  1.000 49.73539 ? 86  ASN B C   1 
ATOM   2404 O O   . ASN B 1 87  ? 16.64740 45.24461 48.49095  1.000 51.21468 ? 86  ASN B O   1 
ATOM   2405 C CB  . ASN B 1 87  ? 15.86682 43.07846 46.17804  1.000 50.43852 ? 86  ASN B CB  1 
ATOM   2406 C CG  . ASN B 1 87  ? 16.37955 42.17854 45.06193  1.000 56.84428 ? 86  ASN B CG  1 
ATOM   2407 O OD1 . ASN B 1 87  ? 16.41646 42.57906 43.89608  1.000 53.05189 ? 86  ASN B OD1 1 
ATOM   2408 N ND2 . ASN B 1 87  ? 16.76931 40.95314 45.41270  1.000 59.06164 ? 86  ASN B ND2 1 
ATOM   2409 N N   . SER B 1 88  ? 14.98919 45.98910 47.14337  1.000 55.77597 ? 87  SER B N   1 
ATOM   2410 C CA  . SER B 1 88  ? 14.40867 46.92513 48.11388  1.000 47.36632 ? 87  SER B CA  1 
ATOM   2411 C C   . SER B 1 88  ? 15.46959 47.88839 48.63463  1.000 47.92542 ? 87  SER B C   1 
ATOM   2412 O O   . SER B 1 88  ? 15.69184 48.02109 49.84033  1.000 50.81054 ? 87  SER B O   1 
ATOM   2413 C CB  . SER B 1 88  ? 13.75643 46.17572 49.27283  1.000 44.45386 ? 87  SER B CB  1 
ATOM   2414 O OG  . SER B 1 88  ? 12.94394 45.12107 48.79732  1.000 50.62224 ? 87  SER B OG  1 
ATOM   2415 N N   . LEU B 1 89  ? 16.12977 48.57119 47.70240  1.000 47.49567 ? 88  LEU B N   1 
ATOM   2416 C CA  . LEU B 1 89  ? 17.21518 49.47562 48.05812  1.000 44.65035 ? 88  LEU B CA  1 
ATOM   2417 C C   . LEU B 1 89  ? 16.68087 50.68757 48.81384  1.000 51.18786 ? 88  LEU B C   1 
ATOM   2418 O O   . LEU B 1 89  ? 15.86728 51.44987 48.28684  1.000 53.49302 ? 88  LEU B O   1 
ATOM   2419 C CB  . LEU B 1 89  ? 17.95329 49.91285 46.80305  1.000 41.87212 ? 88  LEU B CB  1 
ATOM   2420 C CG  . LEU B 1 89  ? 19.12284 49.00195 46.48397  1.000 34.96512 ? 88  LEU B CG  1 
ATOM   2421 C CD1 . LEU B 1 89  ? 19.87376 49.54210 45.29149  1.000 38.49938 ? 88  LEU B CD1 1 
ATOM   2422 C CD2 . LEU B 1 89  ? 20.01745 48.88938 47.70142  1.000 35.35527 ? 88  LEU B CD2 1 
ATOM   2423 N N   . THR B 1 90  ? 17.19643 50.90450 50.01538  1.000 51.51149 ? 89  THR B N   1 
ATOM   2424 C CA  . THR B 1 90  ? 16.85965 52.04862 50.84915  1.000 51.78259 ? 89  THR B CA  1 
ATOM   2425 C C   . THR B 1 90  ? 17.96388 53.10349 50.85058  1.000 51.02584 ? 89  THR B C   1 
ATOM   2426 O O   . THR B 1 90  ? 19.08296 52.88212 50.37979  1.000 54.31606 ? 89  THR B O   1 
ATOM   2427 C CB  . THR B 1 90  ? 16.55912 51.58654 52.28320  1.000 50.11122 ? 89  THR B CB  1 
ATOM   2428 O OG1 . THR B 1 90  ? 16.25734 52.72252 53.09397  1.000 51.95287 ? 89  THR B OG1 1 
ATOM   2429 C CG2 . THR B 1 90  ? 17.72086 50.80792 52.89224  1.000 50.57543 ? 89  THR B CG2 1 
ATOM   2430 N N   . THR B 1 91  ? 17.62094 54.28058 51.38796  1.000 50.81883 ? 90  THR B N   1 
ATOM   2431 C CA  . THR B 1 91  ? 18.59273 55.36511 51.49908  1.000 52.30082 ? 90  THR B CA  1 
ATOM   2432 C C   . THR B 1 91  ? 19.73012 55.01870 52.45184  1.000 48.21696 ? 90  THR B C   1 
ATOM   2433 O O   . THR B 1 91  ? 20.83966 55.54300 52.29120  1.000 44.15740 ? 90  THR B O   1 
ATOM   2434 C CB  . THR B 1 91  ? 17.90275 56.65436 51.94409  1.000 43.57505 ? 90  THR B CB  1 
ATOM   2435 O OG1 . THR B 1 91  ? 18.89290 57.66694 52.16143  1.000 46.75710 ? 90  THR B OG1 1 
ATOM   2436 C CG2 . THR B 1 91  ? 17.10565 56.42110 53.22675  1.000 46.07026 ? 90  THR B CG2 1 
ATOM   2437 N N   . GLU B 1 92  ? 19.49145 54.11908 53.41242  1.000 47.82154 ? 91  GLU B N   1 
ATOM   2438 C CA  . GLU B 1 92  ? 20.58348 53.64986 54.25154  1.000 49.13709 ? 91  GLU B CA  1 
ATOM   2439 C C   . GLU B 1 92  ? 21.55616 52.77321 53.47345  1.000 51.95290 ? 91  GLU B C   1 
ATOM   2440 O O   . GLU B 1 92  ? 22.54024 52.29710 54.05194  1.000 55.22977 ? 91  GLU B O   1 
ATOM   2441 C CB  . GLU B 1 92  ? 20.02491 52.87480 55.44903  1.000 31.75821 ? 91  GLU B CB  1 
ATOM   2442 N N   . ASP B 1 93  ? 21.29860 52.55758 52.18253  1.000 42.22251 ? 92  ASP B N   1 
ATOM   2443 C CA  . ASP B 1 93  ? 22.20082 51.86362 51.28098  1.000 42.52855 ? 92  ASP B CA  1 
ATOM   2444 C C   . ASP B 1 93  ? 22.93311 52.80430 50.32935  1.000 40.99618 ? 92  ASP B C   1 
ATOM   2445 O O   . ASP B 1 93  ? 23.72005 52.33875 49.49393  1.000 37.79126 ? 92  ASP B O   1 
ATOM   2446 C CB  . ASP B 1 93  ? 21.43421 50.79759 50.49431  1.000 44.89658 ? 92  ASP B CB  1 
ATOM   2447 C CG  . ASP B 1 93  ? 20.99227 49.62737 51.37164  1.000 52.78230 ? 92  ASP B CG  1 
ATOM   2448 O OD1 . ASP B 1 93  ? 21.82042 49.12257 52.16252  1.000 53.04245 ? 92  ASP B OD1 1 
ATOM   2449 O OD2 . ASP B 1 93  ? 19.82082 49.19692 51.26996  1.000 54.55515 ? 92  ASP B OD2 1 
ATOM   2450 N N   . THR B 1 94  ? 22.68310 54.10627 50.40735  1.000 42.76096 ? 93  THR B N   1 
ATOM   2451 C CA  . THR B 1 94  ? 23.42935 55.02097 49.55628  1.000 42.25046 ? 93  THR B CA  1 
ATOM   2452 C C   . THR B 1 94  ? 24.90309 54.92529 49.92922  1.000 37.58552 ? 93  THR B C   1 
ATOM   2453 O O   . THR B 1 94  ? 25.27184 55.15633 51.08589  1.000 38.10431 ? 93  THR B O   1 
ATOM   2454 C CB  . THR B 1 94  ? 22.92561 56.46203 49.71767  1.000 39.24183 ? 93  THR B CB  1 
ATOM   2455 O OG1 . THR B 1 94  ? 21.51925 56.53832 49.43766  1.000 39.00496 ? 93  THR B OG1 1 
ATOM   2456 C CG2 . THR B 1 94  ? 23.66743 57.39209 48.77016  1.000 33.45808 ? 93  THR B CG2 1 
ATOM   2457 N N   . ALA B 1 95  ? 25.74028 54.56590 48.95801  1.000 32.86678 ? 94  ALA B N   1 
ATOM   2458 C CA  . ALA B 1 95  ? 27.16824 54.44407 49.20661  1.000 26.30431 ? 94  ALA B CA  1 
ATOM   2459 C C   . ALA B 1 95  ? 27.87830 54.23060 47.88432  1.000 29.90392 ? 94  ALA B C   1 
ATOM   2460 O O   . ALA B 1 95  ? 27.25592 54.00181 46.84229  1.000 30.12198 ? 94  ALA B O   1 
ATOM   2461 C CB  . ALA B 1 95  ? 27.48458 53.29596 50.16036  1.000 30.22874 ? 94  ALA B CB  1 
ATOM   2462 N N   . ILE B 1 96  ? 29.19323 54.32045 47.94556  1.000 23.59632 ? 95  ILE B N   1 
ATOM   2463 C CA  . ILE B 1 96  ? 30.04718 53.83500 46.88415  1.000 25.82226 ? 95  ILE B CA  1 
ATOM   2464 C C   . ILE B 1 96  ? 30.33791 52.37937 47.19019  1.000 33.31545 ? 95  ILE B C   1 
ATOM   2465 O O   . ILE B 1 96  ? 30.70106 52.03742 48.32114  1.000 33.19050 ? 95  ILE B O   1 
ATOM   2466 C CB  . ILE B 1 96  ? 31.34319 54.64314 46.80258  1.000 29.86240 ? 95  ILE B CB  1 
ATOM   2467 C CG1 . ILE B 1 96  ? 31.10503 55.94843 46.06916  1.000 31.60806 ? 95  ILE B CG1 1 
ATOM   2468 C CG2 . ILE B 1 96  ? 32.37894 53.85881 46.04573  1.000 33.01026 ? 95  ILE B CG2 1 
ATOM   2469 C CD1 . ILE B 1 96  ? 32.33631 56.81572 46.04363  1.000 37.83597 ? 95  ILE B CD1 1 
ATOM   2470 N N   . TYR B 1 97  ? 30.17659 51.52025 46.19269  1.000 34.29253 ? 96  TYR B N   1 
ATOM   2471 C CA  . TYR B 1 97  ? 30.26881 50.08157 46.37908  1.000 26.13956 ? 96  TYR B CA  1 
ATOM   2472 C C   . TYR B 1 97  ? 31.56588 49.58789 45.77354  1.000 26.84015 ? 96  TYR B C   1 
ATOM   2473 O O   . TYR B 1 97  ? 31.77144 49.70153 44.56454  1.000 35.48316 ? 96  TYR B O   1 
ATOM   2474 C CB  . TYR B 1 97  ? 29.06047 49.40520 45.74744  1.000 21.88121 ? 96  TYR B CB  1 
ATOM   2475 C CG  . TYR B 1 97  ? 27.87384 49.55146 46.65074  1.000 32.78168 ? 96  TYR B CG  1 
ATOM   2476 C CD1 . TYR B 1 97  ? 27.08618 50.69779 46.62025  1.000 30.53908 ? 96  TYR B CD1 1 
ATOM   2477 C CD2 . TYR B 1 97  ? 27.56946 48.56446 47.58492  1.000 32.26310 ? 96  TYR B CD2 1 
ATOM   2478 C CE1 . TYR B 1 97  ? 26.01153 50.84921 47.48531  1.000 34.71260 ? 96  TYR B CE1 1 
ATOM   2479 C CE2 . TYR B 1 97  ? 26.49491 48.69539 48.43767  1.000 30.77977 ? 96  TYR B CE2 1 
ATOM   2480 C CZ  . TYR B 1 97  ? 25.72103 49.83538 48.39190  1.000 33.39184 ? 96  TYR B CZ  1 
ATOM   2481 O OH  . TYR B 1 97  ? 24.66136 49.95700 49.26109  1.000 32.98401 ? 96  TYR B OH  1 
ATOM   2482 N N   . TYR B 1 98  ? 32.40696 48.98360 46.59676  1.000 29.56860 ? 97  TYR B N   1 
ATOM   2483 C CA  . TYR B 1 98  ? 33.74123 48.58359 46.17622  1.000 33.81073 ? 97  TYR B CA  1 
ATOM   2484 C C   . TYR B 1 98  ? 33.85228 47.06566 46.08935  1.000 31.95038 ? 97  TYR B C   1 
ATOM   2485 O O   . TYR B 1 98  ? 33.32886 46.32958 46.93696  1.000 25.26693 ? 97  TYR B O   1 
ATOM   2486 C CB  . TYR B 1 98  ? 34.81058 49.09399 47.14298  1.000 32.03093 ? 97  TYR B CB  1 
ATOM   2487 C CG  . TYR B 1 98  ? 34.94737 50.58942 47.27793  1.000 31.87911 ? 97  TYR B CG  1 
ATOM   2488 C CD1 . TYR B 1 98  ? 34.54202 51.22852 48.43085  1.000 29.63548 ? 97  TYR B CD1 1 
ATOM   2489 C CD2 . TYR B 1 98  ? 35.53834 51.34428 46.28624  1.000 32.24761 ? 97  TYR B CD2 1 
ATOM   2490 C CE1 . TYR B 1 98  ? 34.67672 52.56653 48.57993  1.000 31.34106 ? 97  TYR B CE1 1 
ATOM   2491 C CE2 . TYR B 1 98  ? 35.68759 52.69253 46.42881  1.000 31.87659 ? 97  TYR B CE2 1 
ATOM   2492 C CZ  . TYR B 1 98  ? 35.25821 53.30619 47.58915  1.000 35.90946 ? 97  TYR B CZ  1 
ATOM   2493 O OH  . TYR B 1 98  ? 35.38553 54.67958 47.75609  1.000 37.05415 ? 97  TYR B OH  1 
ATOM   2494 N N   . CYS B 1 99  ? 34.58588 46.62133 45.08703  1.000 27.81557 ? 98  CYS B N   1 
ATOM   2495 C CA  . CYS B 1 99  ? 34.85144 45.21992 44.84793  1.000 29.20303 ? 98  CYS B CA  1 
ATOM   2496 C C   . CYS B 1 99  ? 36.27216 44.92940 45.29520  1.000 29.87517 ? 98  CYS B C   1 
ATOM   2497 O O   . CYS B 1 99  ? 37.15903 45.76907 45.12192  1.000 36.28159 ? 98  CYS B O   1 
ATOM   2498 C CB  . CYS B 1 99  ? 34.68650 44.90152 43.35980  1.000 32.53168 ? 98  CYS B CB  1 
ATOM   2499 S SG  . CYS B 1 99  ? 34.84075 43.16141 42.94109  1.000 63.16728 ? 98  CYS B SG  1 
ATOM   2500 N N   . ALA B 1 100 ? 36.49299 43.75460 45.88704  1.000 25.38580 ? 99  ALA B N   1 
ATOM   2501 C CA  . ALA B 1 100 ? 37.81368 43.46018 46.42471  1.000 30.82126 ? 99  ALA B CA  1 
ATOM   2502 C C   . ALA B 1 100 ? 38.16739 42.00081 46.19189  1.000 26.68624 ? 99  ALA B C   1 
ATOM   2503 O O   . ALA B 1 100 ? 37.29837 41.13318 46.26472  1.000 21.58801 ? 99  ALA B O   1 
ATOM   2504 C CB  . ALA B 1 100 ? 37.89869 43.77753 47.92205  1.000 23.18750 ? 99  ALA B CB  1 
ATOM   2505 N N   . ARG B 1 101 ? 39.45025 41.75094 45.90752  1.000 22.64526 ? 100 ARG B N   1 
ATOM   2506 C CA  . ARG B 1 101 ? 39.98390 40.40863 45.77023  1.000 21.32372 ? 100 ARG B CA  1 
ATOM   2507 C C   . ARG B 1 101 ? 40.65348 39.99765 47.06790  1.000 27.54483 ? 100 ARG B C   1 
ATOM   2508 O O   . ARG B 1 101 ? 41.51582 40.72198 47.58093  1.000 31.93202 ? 100 ARG B O   1 
ATOM   2509 C CB  . ARG B 1 101 ? 41.01983 40.27849 44.64979  1.000 27.69247 ? 100 ARG B CB  1 
ATOM   2510 C CG  . ARG B 1 101 ? 41.85713 39.04913 44.97442  1.000 24.15156 ? 100 ARG B CG  1 
ATOM   2511 C CD  . ARG B 1 101 ? 42.55599 38.26695 43.91975  1.000 24.32177 ? 100 ARG B CD  1 
ATOM   2512 N NE  . ARG B 1 101 ? 43.80646 38.75176 43.34916  1.000 26.67762 ? 100 ARG B NE  1 
ATOM   2513 C CZ  . ARG B 1 101 ? 44.95109 38.86018 44.01486  1.000 25.96744 ? 100 ARG B CZ  1 
ATOM   2514 N NH1 . ARG B 1 101 ? 45.02604 38.56136 45.30036  1.000 20.52459 ? 100 ARG B NH1 1 
ATOM   2515 N NH2 . ARG B 1 101 ? 46.04131 39.25836 43.38201  1.000 30.63153 ? 100 ARG B NH2 1 
ATOM   2516 N N   . ASP B 1 102 ? 40.33217 38.79009 47.52928  1.000 32.26463 ? 101 ASP B N   1 
ATOM   2517 C CA  . ASP B 1 102 ? 41.03809 38.16311 48.63458  1.000 27.72012 ? 101 ASP B CA  1 
ATOM   2518 C C   . ASP B 1 102 ? 42.54042 38.18601 48.40769  1.000 24.08017 ? 101 ASP B C   1 
ATOM   2519 O O   . ASP B 1 102 ? 43.03634 37.72685 47.38599  1.000 29.20890 ? 101 ASP B O   1 
ATOM   2520 C CB  . ASP B 1 102 ? 40.54126 36.71020 48.76858  1.000 30.31723 ? 101 ASP B CB  1 
ATOM   2521 C CG  . ASP B 1 102 ? 41.02868 36.00617 50.04565  1.000 29.28488 ? 101 ASP B CG  1 
ATOM   2522 O OD1 . ASP B 1 102 ? 41.71144 36.63477 50.85725  1.000 37.47965 ? 101 ASP B OD1 1 
ATOM   2523 O OD2 . ASP B 1 102 ? 40.70814 34.82266 50.26188  1.000 26.28158 ? 101 ASP B OD2 1 
ATOM   2524 N N   . PHE B 1 103 ? 43.25982 38.75370 49.35715  1.000 35.78788 ? 102 PHE B N   1 
ATOM   2525 C CA  . PHE B 1 103 ? 44.68369 38.49883 49.47132  1.000 30.38012 ? 102 PHE B CA  1 
ATOM   2526 C C   . PHE B 1 103 ? 44.80111 37.00366 49.69406  1.000 31.14240 ? 102 PHE B C   1 
ATOM   2527 O O   . PHE B 1 103 ? 44.17307 36.47529 50.61453  1.000 43.24833 ? 102 PHE B O   1 
ATOM   2528 C CB  . PHE B 1 103 ? 45.23875 39.27881 50.66395  1.000 24.41334 ? 102 PHE B CB  1 
ATOM   2529 C CG  . PHE B 1 103 ? 46.70114 39.59497 50.58527  1.000 28.36849 ? 102 PHE B CG  1 
ATOM   2530 C CD1 . PHE B 1 103 ? 47.13798 40.81542 50.08841  1.000 29.69480 ? 102 PHE B CD1 1 
ATOM   2531 C CD2 . PHE B 1 103 ? 47.63858 38.70831 51.06469  1.000 27.03073 ? 102 PHE B CD2 1 
ATOM   2532 C CE1 . PHE B 1 103 ? 48.48285 41.12641 50.04774  1.000 26.23334 ? 102 PHE B CE1 1 
ATOM   2533 C CE2 . PHE B 1 103 ? 48.98681 39.01657 51.01839  1.000 26.71260 ? 102 PHE B CE2 1 
ATOM   2534 C CZ  . PHE B 1 103 ? 49.40711 40.23236 50.51462  1.000 20.58703 ? 102 PHE B CZ  1 
ATOM   2535 N N   . TYR B 1 104 ? 45.52516 36.31291 48.82661  1.000 28.40550 ? 103 TYR B N   1 
ATOM   2536 C CA  . TYR B 1 104 ? 45.67332 34.85362 48.88446  1.000 29.94096 ? 103 TYR B CA  1 
ATOM   2537 C C   . TYR B 1 104 ? 44.58996 34.11088 48.11487  1.000 25.93324 ? 103 TYR B C   1 
ATOM   2538 O O   . TYR B 1 104 ? 43.39802 34.43534 48.17543  1.000 24.71843 ? 103 TYR B O   1 
ATOM   2539 C CB  . TYR B 1 104 ? 45.66995 34.27729 50.30614  1.000 30.84963 ? 103 TYR B CB  1 
ATOM   2540 C CG  . TYR B 1 104 ? 46.56920 34.92317 51.32938  1.000 26.77520 ? 103 TYR B CG  1 
ATOM   2541 C CD1 . TYR B 1 104 ? 47.94303 34.94323 51.15722  1.000 28.68232 ? 103 TYR B CD1 1 
ATOM   2542 C CD2 . TYR B 1 104 ? 46.04166 35.44919 52.50572  1.000 25.05095 ? 103 TYR B CD2 1 
ATOM   2543 C CE1 . TYR B 1 104 ? 48.77511 35.50082 52.10820  1.000 26.78293 ? 103 TYR B CE1 1 
ATOM   2544 C CE2 . TYR B 1 104 ? 46.85659 36.01823 53.45321  1.000 30.08392 ? 103 TYR B CE2 1 
ATOM   2545 C CZ  . TYR B 1 104 ? 48.23004 36.03310 53.25706  1.000 27.27946 ? 103 TYR B CZ  1 
ATOM   2546 O OH  . TYR B 1 104 ? 49.05564 36.58989 54.21186  1.000 23.97704 ? 103 TYR B OH  1 
ATOM   2547 N N   . ASP B 1 105 ? 45.01981 33.05408 47.45205  1.000 27.77320 ? 104 ASP B N   1 
ATOM   2548 C CA  . ASP B 1 105 ? 44.16586 32.09853 46.78187  1.000 27.11611 ? 104 ASP B CA  1 
ATOM   2549 C C   . ASP B 1 105 ? 43.62286 31.08410 47.78696  1.000 29.13820 ? 104 ASP B C   1 
ATOM   2550 O O   . ASP B 1 105 ? 43.98849 31.07524 48.96570  1.000 31.20016 ? 104 ASP B O   1 
ATOM   2551 C CB  . ASP B 1 105 ? 44.96712 31.40791 45.69333  1.000 29.01990 ? 104 ASP B CB  1 
ATOM   2552 C CG  . ASP B 1 105 ? 46.26422 30.81023 46.22873  1.000 32.29784 ? 104 ASP B CG  1 
ATOM   2553 O OD1 . ASP B 1 105 ? 46.50196 30.85842 47.45187  1.000 30.72299 ? 104 ASP B OD1 1 
ATOM   2554 O OD2 . ASP B 1 105 ? 47.07757 30.32062 45.42421  1.000 41.60674 ? 104 ASP B OD2 1 
ATOM   2555 N N   . PHE B 1 106 ? 42.72153 30.22526 47.31523  1.000 30.88793 ? 105 PHE B N   1 
ATOM   2556 C CA  . PHE B 1 106 ? 42.03574 29.32882 48.23422  1.000 24.35688 ? 105 PHE B CA  1 
ATOM   2557 C C   . PHE B 1 106 ? 43.00123 28.36447 48.89732  1.000 28.47823 ? 105 PHE B C   1 
ATOM   2558 O O   . PHE B 1 106 ? 42.68278 27.79010 49.94572  1.000 26.28061 ? 105 PHE B O   1 
ATOM   2559 C CB  . PHE B 1 106 ? 40.92710 28.57841 47.51183  1.000 22.71002 ? 105 PHE B CB  1 
ATOM   2560 C CG  . PHE B 1 106 ? 41.41285 27.63082 46.46301  1.000 26.62561 ? 105 PHE B CG  1 
ATOM   2561 C CD1 . PHE B 1 106 ? 41.67619 28.06888 45.18772  1.000 28.01879 ? 105 PHE B CD1 1 
ATOM   2562 C CD2 . PHE B 1 106 ? 41.57873 26.28521 46.74863  1.000 29.86103 ? 105 PHE B CD2 1 
ATOM   2563 C CE1 . PHE B 1 106 ? 42.12079 27.17502 44.22556  1.000 33.20254 ? 105 PHE B CE1 1 
ATOM   2564 C CE2 . PHE B 1 106 ? 42.02062 25.39610 45.79266  1.000 27.06975 ? 105 PHE B CE2 1 
ATOM   2565 C CZ  . PHE B 1 106 ? 42.29459 25.83303 44.53937  1.000 25.85457 ? 105 PHE B CZ  1 
ATOM   2566 N N   . TRP B 1 107 ? 44.17750 28.17876 48.31210  1.000 28.43694 ? 106 TRP B N   1 
ATOM   2567 C CA  . TRP B 1 107 ? 45.12699 27.24258 48.88512  1.000 27.48177 ? 106 TRP B CA  1 
ATOM   2568 C C   . TRP B 1 107 ? 45.48482 27.62815 50.30538  1.000 26.20583 ? 106 TRP B C   1 
ATOM   2569 O O   . TRP B 1 107 ? 45.60896 26.76501 51.17683  1.000 28.87195 ? 106 TRP B O   1 
ATOM   2570 C CB  . TRP B 1 107 ? 46.37802 27.19138 48.02464  1.000 28.64650 ? 106 TRP B CB  1 
ATOM   2571 C CG  . TRP B 1 107 ? 46.17155 26.58536 46.68644  1.000 31.71797 ? 106 TRP B CG  1 
ATOM   2572 C CD1 . TRP B 1 107 ? 46.32123 27.19999 45.48066  1.000 33.50142 ? 106 TRP B CD1 1 
ATOM   2573 C CD2 . TRP B 1 107 ? 45.80128 25.23101 46.40380  1.000 33.28040 ? 106 TRP B CD2 1 
ATOM   2574 N NE1 . TRP B 1 107 ? 46.06904 26.31357 44.46380  1.000 35.54905 ? 106 TRP B NE1 1 
ATOM   2575 C CE2 . TRP B 1 107 ? 45.74883 25.09649 45.00660  1.000 35.91207 ? 106 TRP B CE2 1 
ATOM   2576 C CE3 . TRP B 1 107 ? 45.51006 24.11889 47.19751  1.000 30.67760 ? 106 TRP B CE3 1 
ATOM   2577 C CZ2 . TRP B 1 107 ? 45.41983 23.89755 44.38960  1.000 32.15183 ? 106 TRP B CZ2 1 
ATOM   2578 C CZ3 . TRP B 1 107 ? 45.19332 22.93587 46.58561  1.000 27.68370 ? 106 TRP B CZ3 1 
ATOM   2579 C CH2 . TRP B 1 107 ? 45.14798 22.83240 45.19779  1.000 35.37152 ? 106 TRP B CH2 1 
ATOM   2580 N N   . ASN B 1 108 ? 45.62686 28.92089 50.56000  1.000 29.88936 ? 107 ASN B N   1 
ATOM   2581 C CA  . ASN B 1 108 ? 46.33014 29.38942 51.73908  1.000 27.11152 ? 107 ASN B CA  1 
ATOM   2582 C C   . ASN B 1 108 ? 45.47373 29.29873 52.99180  1.000 29.45187 ? 107 ASN B C   1 
ATOM   2583 O O   . ASN B 1 108 ? 44.26079 29.51175 52.95231  1.000 33.89590 ? 107 ASN B O   1 
ATOM   2584 C CB  . ASN B 1 108 ? 46.79168 30.82846 51.54507  1.000 27.72548 ? 107 ASN B CB  1 
ATOM   2585 C CG  . ASN B 1 108 ? 47.86326 31.21073 52.52663  1.000 31.57364 ? 107 ASN B CG  1 
ATOM   2586 O OD1 . ASN B 1 108 ? 47.60794 31.32950 53.72315  1.000 30.52640 ? 107 ASN B OD1 1 
ATOM   2587 N ND2 . ASN B 1 108 ? 49.08148 31.37627 52.03452  1.000 31.00496 ? 107 ASN B ND2 1 
ATOM   2588 N N   . GLU B 1 109 ? 46.12157 28.95884 54.10878  1.000 29.47442 ? 108 GLU B N   1 
ATOM   2589 C CA  . GLU B 1 109 ? 45.42956 28.92715 55.38970  1.000 34.41946 ? 108 GLU B CA  1 
ATOM   2590 C C   . GLU B 1 109 ? 44.89975 30.29789 55.77904  1.000 37.42238 ? 108 GLU B C   1 
ATOM   2591 O O   . GLU B 1 109 ? 43.84013 30.39763 56.41394  1.000 33.28988 ? 108 GLU B O   1 
ATOM   2592 C CB  . GLU B 1 109 ? 46.35717 28.41109 56.48080  1.000 40.74036 ? 108 GLU B CB  1 
ATOM   2593 C CG  . GLU B 1 109 ? 45.58908 27.98931 57.71421  1.000 49.94091 ? 108 GLU B CG  1 
ATOM   2594 C CD  . GLU B 1 109 ? 46.47689 27.37152 58.77178  1.000 55.25670 ? 108 GLU B CD  1 
ATOM   2595 O OE1 . GLU B 1 109 ? 47.71523 27.34912 58.56027  1.000 53.83479 ? 108 GLU B OE1 1 
ATOM   2596 O OE2 . GLU B 1 109 ? 45.93239 26.91825 59.81126  1.000 52.50340 ? 108 GLU B OE2 1 
ATOM   2597 N N   . PHE B 1 110 ? 45.62489 31.35817 55.40328  1.000 32.98825 ? 109 PHE B N   1 
ATOM   2598 C CA  . PHE B 1 110 ? 45.33545 32.72583 55.80010  1.000 29.63708 ? 109 PHE B CA  1 
ATOM   2599 C C   . PHE B 1 110 ? 44.30803 33.39477 54.89943  1.000 35.07832 ? 109 PHE B C   1 
ATOM   2600 O O   . PHE B 1 110 ? 44.01002 34.57457 55.11662  1.000 40.18105 ? 109 PHE B O   1 
ATOM   2601 C CB  . PHE B 1 110 ? 46.61368 33.56724 55.72390  1.000 28.65156 ? 109 PHE B CB  1 
ATOM   2602 C CG  . PHE B 1 110 ? 47.67100 33.22103 56.73892  1.000 36.90929 ? 109 PHE B CG  1 
ATOM   2603 C CD1 . PHE B 1 110 ? 48.15157 34.19354 57.61357  1.000 36.66522 ? 109 PHE B CD1 1 
ATOM   2604 C CD2 . PHE B 1 110 ? 48.22156 31.95618 56.79389  1.000 39.15934 ? 109 PHE B CD2 1 
ATOM   2605 C CE1 . PHE B 1 110 ? 49.13843 33.90202 58.53246  1.000 38.33038 ? 109 PHE B CE1 1 
ATOM   2606 C CE2 . PHE B 1 110 ? 49.20790 31.65136 57.71792  1.000 38.99122 ? 109 PHE B CE2 1 
ATOM   2607 C CZ  . PHE B 1 110 ? 49.66501 32.62302 58.58776  1.000 44.60842 ? 109 PHE B CZ  1 
ATOM   2608 N N   . SER B 1 111 ? 43.72148 32.66518 53.94695  1.000 27.36449 ? 110 SER B N   1 
ATOM   2609 C CA  . SER B 1 111 ? 42.72843 33.22194 53.04543  1.000 28.82514 ? 110 SER B CA  1 
ATOM   2610 C C   . SER B 1 111 ? 41.47220 33.64177 53.81240  1.000 30.51149 ? 110 SER B C   1 
ATOM   2611 O O   . SER B 1 111 ? 41.28570 33.31503 54.98278  1.000 30.29289 ? 110 SER B O   1 
ATOM   2612 C CB  . SER B 1 111 ? 42.37305 32.21246 51.95929  1.000 32.81297 ? 110 SER B CB  1 
ATOM   2613 O OG  . SER B 1 111 ? 41.86538 31.01449 52.52260  1.000 35.48612 ? 110 SER B OG  1 
ATOM   2614 N N   . HIS B 1 112 ? 40.59471 34.36975 53.11650  1.000 34.66219 ? 111 HIS B N   1 
ATOM   2615 C CA  . HIS B 1 112 ? 39.34154 34.89094 53.67259  1.000 30.35422 ? 111 HIS B CA  1 
ATOM   2616 C C   . HIS B 1 112 ? 39.58549 35.86623 54.81702  1.000 34.24359 ? 111 HIS B C   1 
ATOM   2617 O O   . HIS B 1 112 ? 38.71195 36.08039 55.65520  1.000 34.82297 ? 111 HIS B O   1 
ATOM   2618 C CB  . HIS B 1 112 ? 38.42397 33.76111 54.15029  1.000 31.30262 ? 111 HIS B CB  1 
ATOM   2619 C CG  . HIS B 1 112 ? 38.13211 32.72389 53.10483  1.000 39.01770 ? 111 HIS B CG  1 
ATOM   2620 N ND1 . HIS B 1 112 ? 37.17938 31.74351 53.27654  1.000 36.25417 ? 111 HIS B ND1 1 
ATOM   2621 C CD2 . HIS B 1 112 ? 38.65304 32.52468 51.87000  1.000 37.17053 ? 111 HIS B CD2 1 
ATOM   2622 C CE1 . HIS B 1 112 ? 37.13360 30.98308 52.19782  1.000 33.71552 ? 111 HIS B CE1 1 
ATOM   2623 N NE2 . HIS B 1 112 ? 38.01749 31.43478 51.32875  1.000 30.26087 ? 111 HIS B NE2 1 
ATOM   2624 N N   . ARG B 1 113 ? 40.72447 36.51909 54.82641  1.000 30.81641 ? 112 ARG B N   1 
ATOM   2625 C CA  . ARG B 1 113 ? 41.02512 37.35639 55.97475  1.000 34.51087 ? 112 ARG B CA  1 
ATOM   2626 C C   . ARG B 1 113 ? 41.39142 38.77249 55.58800  1.000 36.27446 ? 112 ARG B C   1 
ATOM   2627 O O   . ARG B 1 113 ? 40.98825 39.71974 56.26645  1.000 27.99777 ? 112 ARG B O   1 
ATOM   2628 C CB  . ARG B 1 113 ? 42.18280 36.75213 56.76721  1.000 39.35077 ? 112 ARG B CB  1 
ATOM   2629 C CG  . ARG B 1 113 ? 41.81894 35.53214 57.58540  1.000 41.56905 ? 112 ARG B CG  1 
ATOM   2630 C CD  . ARG B 1 113 ? 40.48540 35.70737 58.27131  1.000 36.65334 ? 112 ARG B CD  1 
ATOM   2631 N NE  . ARG B 1 113 ? 40.10112 34.48084 58.94247  1.000 38.01958 ? 112 ARG B NE  1 
ATOM   2632 C CZ  . ARG B 1 113 ? 39.05366 33.74697 58.59320  1.000 41.93783 ? 112 ARG B CZ  1 
ATOM   2633 N NH1 . ARG B 1 113 ? 38.77184 32.63545 59.25897  1.000 39.91064 ? 112 ARG B NH1 1 
ATOM   2634 N NH2 . ARG B 1 113 ? 38.27366 34.14502 57.59671  1.000 40.13857 ? 112 ARG B NH2 1 
ATOM   2635 N N   . THR B 1 114 ? 42.11631 38.93392 54.49651  1.000 37.46064 ? 113 THR B N   1 
ATOM   2636 C CA  . THR B 1 114 ? 42.66161 40.20404 54.06726  1.000 31.07410 ? 113 THR B CA  1 
ATOM   2637 C C   . THR B 1 114 ? 42.26895 40.41234 52.61489  1.000 35.64843 ? 113 THR B C   1 
ATOM   2638 O O   . THR B 1 114 ? 42.38248 39.49456 51.79729  1.000 34.68705 ? 113 THR B O   1 
ATOM   2639 C CB  . THR B 1 114 ? 44.16690 40.18809 54.19062  1.000 29.84881 ? 113 THR B CB  1 
ATOM   2640 O OG1 . THR B 1 114 ? 44.51499 39.56019 55.42246  1.000 35.15490 ? 113 THR B OG1 1 
ATOM   2641 C CG2 . THR B 1 114 ? 44.69998 41.58781 54.18497  1.000 27.11793 ? 113 THR B CG2 1 
ATOM   2642 N N   . PHE B 1 115 ? 41.83391 41.61833 52.28605  1.000 35.50888 ? 114 PHE B N   1 
ATOM   2643 C CA  . PHE B 1 115 ? 41.33450 41.90329 50.95139  1.000 32.93702 ? 114 PHE B CA  1 
ATOM   2644 C C   . PHE B 1 115 ? 42.08502 43.07748 50.35285  1.000 32.89259 ? 114 PHE B C   1 
ATOM   2645 O O   . PHE B 1 115 ? 42.52825 43.98301 51.06131  1.000 35.09515 ? 114 PHE B O   1 
ATOM   2646 C CB  . PHE B 1 115 ? 39.84498 42.15578 50.98074  1.000 27.19891 ? 114 PHE B CB  1 
ATOM   2647 C CG  . PHE B 1 115 ? 39.07712 40.95562 51.37816  1.000 32.03206 ? 114 PHE B CG  1 
ATOM   2648 C CD1 . PHE B 1 115 ? 38.90465 40.64568 52.71213  1.000 31.79110 ? 114 PHE B CD1 1 
ATOM   2649 C CD2 . PHE B 1 115 ? 38.57983 40.08766 50.40829  1.000 34.00267 ? 114 PHE B CD2 1 
ATOM   2650 C CE1 . PHE B 1 115 ? 38.20309 39.52452 53.06648  1.000 38.45973 ? 114 PHE B CE1 1 
ATOM   2651 C CE2 . PHE B 1 115 ? 37.88022 38.96564 50.75278  1.000 26.28947 ? 114 PHE B CE2 1 
ATOM   2652 C CZ  . PHE B 1 115 ? 37.68936 38.67528 52.07456  1.000 32.18538 ? 114 PHE B CZ  1 
ATOM   2653 N N   . ASP B 1 116 ? 42.24981 43.03633 49.03724  1.000 33.77891 ? 115 ASP B N   1 
ATOM   2654 C CA  . ASP B 1 116 ? 43.12248 43.96953 48.34808  1.000 36.00884 ? 115 ASP B CA  1 
ATOM   2655 C C   . ASP B 1 116 ? 42.47115 44.36040 47.02917  1.000 30.91225 ? 115 ASP B C   1 
ATOM   2656 O O   . ASP B 1 116 ? 41.31231 44.02619 46.76554  1.000 30.51189 ? 115 ASP B O   1 
ATOM   2657 C CB  . ASP B 1 116 ? 44.50228 43.32667 48.14576  1.000 31.41162 ? 115 ASP B CB  1 
ATOM   2658 C CG  . ASP B 1 116 ? 45.64026 44.34055 48.16677  1.000 36.64918 ? 115 ASP B CG  1 
ATOM   2659 O OD1 . ASP B 1 116 ? 45.41744 45.54046 47.84325  1.000 26.23829 ? 115 ASP B OD1 1 
ATOM   2660 O OD2 . ASP B 1 116 ? 46.77329 43.90906 48.49480  1.000 40.54948 ? 115 ASP B OD2 1 
ATOM   2661 N N   . PHE B 1 117 ? 43.22143 45.13019 46.23595  1.000 31.19914 ? 116 PHE B N   1 
ATOM   2662 C CA  . PHE B 1 117 ? 42.90672 45.39646 44.83321  1.000 34.18637 ? 116 PHE B CA  1 
ATOM   2663 C C   . PHE B 1 117 ? 41.53283 46.01840 44.64924  1.000 39.27648 ? 116 PHE B C   1 
ATOM   2664 O O   . PHE B 1 117 ? 40.81095 45.70013 43.69890  1.000 42.44738 ? 116 PHE B O   1 
ATOM   2665 C CB  . PHE B 1 117 ? 43.05884 44.11898 44.00710  1.000 32.57483 ? 116 PHE B CB  1 
ATOM   2666 C CG  . PHE B 1 117 ? 44.39471 43.50729 44.17345  1.000 29.77200 ? 116 PHE B CG  1 
ATOM   2667 C CD1 . PHE B 1 117 ? 44.56266 42.37494 44.94583  1.000 34.03513 ? 116 PHE B CD1 1 
ATOM   2668 C CD2 . PHE B 1 117 ? 45.50126 44.12857 43.64438  1.000 25.87914 ? 116 PHE B CD2 1 
ATOM   2669 C CE1 . PHE B 1 117 ? 45.81784 41.85082 45.15661  1.000 31.43474 ? 116 PHE B CE1 1 
ATOM   2670 C CE2 . PHE B 1 117 ? 46.75039 43.61071 43.84023  1.000 30.35871 ? 116 PHE B CE2 1 
ATOM   2671 C CZ  . PHE B 1 117 ? 46.91241 42.46311 44.59599  1.000 29.16027 ? 116 PHE B CZ  1 
ATOM   2672 N N   . TRP B 1 118 ? 41.14969 46.87824 45.58747  1.000 37.96944 ? 117 TRP B N   1 
ATOM   2673 C CA  . TRP B 1 118 ? 39.88827 47.58272 45.45083  1.000 35.41868 ? 117 TRP B CA  1 
ATOM   2674 C C   . TRP B 1 118 ? 39.86757 48.27816 44.10005  1.000 39.27375 ? 117 TRP B C   1 
ATOM   2675 O O   . TRP B 1 118 ? 40.87433 48.85657 43.67291  1.000 44.46583 ? 117 TRP B O   1 
ATOM   2676 C CB  . TRP B 1 118 ? 39.71124 48.56760 46.60782  1.000 33.64943 ? 117 TRP B CB  1 
ATOM   2677 C CG  . TRP B 1 118 ? 39.68990 47.86986 47.94018  1.000 28.24424 ? 117 TRP B CG  1 
ATOM   2678 C CD1 . TRP B 1 118 ? 40.54122 46.89169 48.36606  1.000 32.44750 ? 117 TRP B CD1 1 
ATOM   2679 C CD2 . TRP B 1 118 ? 38.75887 48.07980 49.01209  1.000 30.08785 ? 117 TRP B CD2 1 
ATOM   2680 N NE1 . TRP B 1 118 ? 40.20119 46.48131 49.63329  1.000 35.79735 ? 117 TRP B NE1 1 
ATOM   2681 C CE2 . TRP B 1 118 ? 39.11518 47.20196 50.05487  1.000 28.77662 ? 117 TRP B CE2 1 
ATOM   2682 C CE3 . TRP B 1 118 ? 37.66871 48.93322 49.19674  1.000 30.77909 ? 117 TRP B CE3 1 
ATOM   2683 C CZ2 . TRP B 1 118 ? 38.42218 47.15352 51.25257  1.000 25.60600 ? 117 TRP B CZ2 1 
ATOM   2684 C CZ3 . TRP B 1 118 ? 36.98026 48.87700 50.38646  1.000 27.89413 ? 117 TRP B CZ3 1 
ATOM   2685 C CH2 . TRP B 1 118 ? 37.36042 47.99944 51.39758  1.000 27.94434 ? 117 TRP B CH2 1 
ATOM   2686 N N   . GLY B 1 119 ? 38.71080 48.23161 43.43249  1.000 38.37773 ? 118 GLY B N   1 
ATOM   2687 C CA  . GLY B 1 119 ? 38.61993 48.79107 42.09393  1.000 43.21391 ? 118 GLY B CA  1 
ATOM   2688 C C   . GLY B 1 119 ? 38.63864 50.30311 42.08023  1.000 42.58868 ? 118 GLY B C   1 
ATOM   2689 O O   . GLY B 1 119 ? 39.70727 50.91535 42.01225  1.000 39.42688 ? 118 GLY B O   1 
ATOM   2690 N N   . GLN B 1 120 ? 37.46068 50.91311 42.07884  1.000 41.44686 ? 119 GLN B N   1 
ATOM   2691 C CA  . GLN B 1 120 ? 37.34191 52.35374 42.26030  1.000 40.42674 ? 119 GLN B CA  1 
ATOM   2692 C C   . GLN B 1 120 ? 36.01976 52.61449 42.95822  1.000 38.79813 ? 119 GLN B C   1 
ATOM   2693 O O   . GLN B 1 120 ? 35.85036 53.63326 43.63523  1.000 37.00950 ? 119 GLN B O   1 
ATOM   2694 C CB  . GLN B 1 120 ? 37.43010 53.12375 40.93691  1.000 43.72522 ? 119 GLN B CB  1 
ATOM   2695 C CG  . GLN B 1 120 ? 38.83091 53.17798 40.28989  1.000 54.37995 ? 119 GLN B CG  1 
ATOM   2696 C CD  . GLN B 1 120 ? 39.10985 54.48107 39.52185  1.000 55.80021 ? 119 GLN B CD  1 
ATOM   2697 O OE1 . GLN B 1 120 ? 38.20652 55.09944 38.94417  1.000 48.73472 ? 119 GLN B OE1 1 
ATOM   2698 N NE2 . GLN B 1 120 ? 40.36907 54.91188 39.54434  1.000 55.60674 ? 119 GLN B NE2 1 
ATOM   2699 N N   . GLY B 1 121 ? 35.08523 51.68564 42.81041  1.000 32.32200 ? 120 GLY B N   1 
ATOM   2700 C CA  . GLY B 1 121 ? 33.74934 51.87638 43.32530  1.000 30.85582 ? 120 GLY B CA  1 
ATOM   2701 C C   . GLY B 1 121 ? 32.80184 52.45375 42.28810  1.000 34.52173 ? 120 GLY B C   1 
ATOM   2702 O O   . GLY B 1 121 ? 33.20096 53.05529 41.29398  1.000 33.81913 ? 120 GLY B O   1 
ATOM   2703 N N   . THR B 1 122 ? 31.51612 52.22733 42.52364  1.000 33.13596 ? 121 THR B N   1 
ATOM   2704 C CA  . THR B 1 122 ? 30.45355 52.83428 41.74276  1.000 28.07031 ? 121 THR B CA  1 
ATOM   2705 C C   . THR B 1 122 ? 29.36033 53.31468 42.68691  1.000 29.96356 ? 121 THR B C   1 
ATOM   2706 O O   . THR B 1 122 ? 28.93463 52.56928 43.57046  1.000 26.54406 ? 121 THR B O   1 
ATOM   2707 C CB  . THR B 1 122 ? 29.92159 51.83944 40.71497  1.000 32.25214 ? 121 THR B CB  1 
ATOM   2708 O OG1 . THR B 1 122 ? 28.77448 52.38671 40.07083  1.000 35.77398 ? 121 THR B OG1 1 
ATOM   2709 C CG2 . THR B 1 122 ? 29.60070 50.51454 41.36138  1.000 37.58841 ? 121 THR B CG2 1 
ATOM   2710 N N   . LEU B 1 123 ? 28.90039 54.54633 42.49335  1.000 25.90779 ? 122 LEU B N   1 
ATOM   2711 C CA  . LEU B 1 123 ? 27.98611 55.19120 43.42594  1.000 30.54594 ? 122 LEU B CA  1 
ATOM   2712 C C   . LEU B 1 123 ? 26.56920 54.65396 43.25260  1.000 33.60424 ? 122 LEU B C   1 
ATOM   2713 O O   . LEU B 1 123 ? 26.08631 54.52574 42.12555  1.000 33.42585 ? 122 LEU B O   1 
ATOM   2714 C CB  . LEU B 1 123 ? 27.95621 56.70000 43.16391  1.000 37.83752 ? 122 LEU B CB  1 
ATOM   2715 C CG  . LEU B 1 123 ? 27.16388 57.67261 44.06393  1.000 35.03081 ? 122 LEU B CG  1 
ATOM   2716 C CD1 . LEU B 1 123 ? 27.82315 57.93815 45.41333  1.000 32.25526 ? 122 LEU B CD1 1 
ATOM   2717 C CD2 . LEU B 1 123 ? 26.73655 58.95637 43.36515  1.000 38.59861 ? 122 LEU B CD2 1 
ATOM   2718 N N   . VAL B 1 124 ? 25.90750 54.33515 44.36514  1.000 35.50763 ? 123 VAL B N   1 
ATOM   2719 C CA  . VAL B 1 124 ? 24.47212 54.06258 44.38458  1.000 35.03236 ? 123 VAL B CA  1 
ATOM   2720 C C   . VAL B 1 124 ? 23.80587 55.11484 45.26392  1.000 39.20956 ? 123 VAL B C   1 
ATOM   2721 O O   . VAL B 1 124 ? 24.16445 55.25738 46.43902  1.000 40.77327 ? 123 VAL B O   1 
ATOM   2722 C CB  . VAL B 1 124 ? 24.14328 52.64859 44.88246  1.000 37.11121 ? 123 VAL B CB  1 
ATOM   2723 C CG1 . VAL B 1 124 ? 22.64877 52.41479 44.78444  1.000 38.45528 ? 123 VAL B CG1 1 
ATOM   2724 C CG2 . VAL B 1 124 ? 24.87127 51.60543 44.04826  1.000 41.62598 ? 123 VAL B CG2 1 
ATOM   2725 N N   . THR B 1 125 ? 22.86923 55.87375 44.68421  1.000 37.63307 ? 124 THR B N   1 
ATOM   2726 C CA  . THR B 1 125 ? 22.09197 56.89308 45.38369  1.000 37.44400 ? 124 THR B CA  1 
ATOM   2727 C C   . THR B 1 125 ? 20.61394 56.51071 45.44591  1.000 39.20653 ? 124 THR B C   1 
ATOM   2728 O O   . THR B 1 125 ? 20.07034 55.97195 44.47687  1.000 39.60255 ? 124 THR B O   1 
ATOM   2729 C CB  . THR B 1 125 ? 22.24140 58.25471 44.69553  1.000 36.11592 ? 124 THR B CB  1 
ATOM   2730 O OG1 . THR B 1 125 ? 23.62217 58.62977 44.65027  1.000 35.67958 ? 124 THR B OG1 1 
ATOM   2731 C CG2 . THR B 1 125 ? 21.47272 59.34511 45.43776  1.000 34.54134 ? 124 THR B CG2 1 
ATOM   2732 N N   . VAL B 1 126 ? 19.97828 56.74272 46.60238  1.000 39.56789 ? 125 VAL B N   1 
ATOM   2733 C CA  . VAL B 1 126 ? 18.55386 56.46008 46.80666  1.000 42.27923 ? 125 VAL B CA  1 
ATOM   2734 C C   . VAL B 1 126 ? 17.82249 57.73736 47.23252  1.000 36.38487 ? 125 VAL B C   1 
ATOM   2735 O O   . VAL B 1 126 ? 18.14541 58.33807 48.26254  1.000 39.95658 ? 125 VAL B O   1 
ATOM   2736 C CB  . VAL B 1 126 ? 18.32306 55.32544 47.81661  1.000 46.80853 ? 125 VAL B CB  1 
ATOM   2737 C CG1 . VAL B 1 126 ? 16.86129 55.29639 48.23989  1.000 48.01641 ? 125 VAL B CG1 1 
ATOM   2738 C CG2 . VAL B 1 126 ? 18.70219 53.99126 47.19470  1.000 43.01961 ? 125 VAL B CG2 1 
ATOM   2739 N N   . SER B 1 127 ? 16.80052 58.10371 46.46135  1.000 42.12585 ? 126 SER B N   1 
ATOM   2740 C CA  . SER B 1 127 ? 16.08283 59.37696 46.47710  1.000 47.04042 ? 126 SER B CA  1 
ATOM   2741 C C   . SER B 1 127 ? 15.29880 59.73029 47.73291  1.000 50.79368 ? 126 SER B C   1 
ATOM   2742 O O   . SER B 1 127 ? 15.84875 60.17752 48.74411  1.000 51.48736 ? 126 SER B O   1 
ATOM   2743 C CB  . SER B 1 127 ? 15.07815 59.38387 45.32326  1.000 54.08344 ? 126 SER B CB  1 
ATOM   2744 O OG  . SER B 1 127 ? 15.69814 59.08779 44.08883  1.000 53.14012 ? 126 SER B OG  1 
ATOM   2745 N N   . SER B 1 128 ? 13.97818 59.61410 47.60153  1.000 58.45896 ? 127 SER B N   1 
ATOM   2746 C CA  . SER B 1 128 ? 13.00371 59.81720 48.66535  1.000 61.13599 ? 127 SER B CA  1 
ATOM   2747 C C   . SER B 1 128 ? 12.70844 58.51866 49.41051  1.000 68.75323 ? 127 SER B C   1 
ATOM   2748 O O   . SER B 1 128 ? 11.56879 58.25925 49.80271  1.000 64.83502 ? 127 SER B O   1 
ATOM   2749 C CB  . SER B 1 128 ? 11.70865 60.38148 48.08403  1.000 55.26789 ? 127 SER B CB  1 
ATOM   2750 O OG  . SER B 1 128 ? 11.84450 61.76148 47.80691  1.000 69.42729 ? 127 SER B OG  1 
ATOM   2751 N N   . ALA B 1 151 ? 31.41180 48.81810 66.23135  1.000 41.16676 ? 150 ALA B N   1 
ATOM   2752 C CA  . ALA B 1 151 ? 32.45167 49.37226 65.37439  1.000 36.99707 ? 150 ALA B CA  1 
ATOM   2753 C C   . ALA B 1 151 ? 33.79908 49.34359 66.08375  1.000 38.88192 ? 150 ALA B C   1 
ATOM   2754 O O   . ALA B 1 151 ? 33.89849 48.93718 67.22620  1.000 40.40930 ? 150 ALA B O   1 
ATOM   2755 C CB  . ALA B 1 151 ? 32.10410 50.78969 64.96221  1.000 34.33010 ? 150 ALA B CB  1 
ATOM   2756 N N   . LEU B 1 152 ? 34.82960 49.81059 65.39666  1.000 38.19696 ? 151 LEU B N   1 
ATOM   2757 C CA  . LEU B 1 152 ? 36.13226 50.03867 65.99520  1.000 35.49831 ? 151 LEU B CA  1 
ATOM   2758 C C   . LEU B 1 152 ? 36.32194 51.54253 66.13099  1.000 34.73424 ? 151 LEU B C   1 
ATOM   2759 O O   . LEU B 1 152 ? 35.86517 52.30408 65.27331  1.000 34.84775 ? 151 LEU B O   1 
ATOM   2760 C CB  . LEU B 1 152 ? 37.22767 49.46336 65.09014  1.000 33.55557 ? 151 LEU B CB  1 
ATOM   2761 C CG  . LEU B 1 152 ? 37.19450 47.96451 64.78928  1.000 33.86107 ? 151 LEU B CG  1 
ATOM   2762 C CD1 . LEU B 1 152 ? 38.25477 47.54618 63.75736  1.000 33.25172 ? 151 LEU B CD1 1 
ATOM   2763 C CD2 . LEU B 1 152 ? 37.34982 47.15634 66.05493  1.000 41.10579 ? 151 LEU B CD2 1 
ATOM   2764 N N   . THR B 1 153 ? 36.98389 51.97248 67.20563  1.000 30.84011 ? 152 THR B N   1 
ATOM   2765 C CA  . THR B 1 153 ? 37.10602 53.39013 67.53549  1.000 29.65304 ? 152 THR B CA  1 
ATOM   2766 C C   . THR B 1 153 ? 38.44327 53.95524 67.08423  1.000 31.75605 ? 152 THR B C   1 
ATOM   2767 O O   . THR B 1 153 ? 39.49965 53.38901 67.37671  1.000 35.31239 ? 152 THR B O   1 
ATOM   2768 C CB  . THR B 1 153 ? 36.89359 53.64433 69.02291  1.000 34.12755 ? 152 THR B CB  1 
ATOM   2769 O OG1 . THR B 1 153 ? 35.58850 53.17436 69.37740  1.000 33.92947 ? 152 THR B OG1 1 
ATOM   2770 C CG2 . THR B 1 153 ? 36.99586 55.14526 69.32623  1.000 24.51470 ? 152 THR B CG2 1 
ATOM   2771 N N   . GLN B 1 154 ? 38.38156 55.11185 66.42560  1.000 33.67662 ? 153 GLN B N   1 
ATOM   2772 C CA  . GLN B 1 154 ? 39.45829 55.71006 65.67839  1.000 31.87434 ? 153 GLN B CA  1 
ATOM   2773 C C   . GLN B 1 154 ? 39.47747 57.20682 65.96722  1.000 28.28818 ? 153 GLN B C   1 
ATOM   2774 O O   . GLN B 1 154 ? 38.40957 57.84811 65.92711  1.000 31.97154 ? 153 GLN B O   1 
ATOM   2775 C CB  . GLN B 1 154 ? 39.21722 55.45209 64.18651  1.000 29.72411 ? 153 GLN B CB  1 
ATOM   2776 C CG  . GLN B 1 154 ? 40.41178 55.64060 63.26478  1.000 30.46501 ? 153 GLN B CG  1 
ATOM   2777 C CD  . GLN B 1 154 ? 40.43570 54.59376 62.16207  1.000 25.34550 ? 153 GLN B CD  1 
ATOM   2778 O OE1 . GLN B 1 154 ? 39.40311 54.05257 61.79297  1.000 21.41618 ? 153 GLN B OE1 1 
ATOM   2779 N NE2 . GLN B 1 154 ? 41.62542 54.28006 61.66399  1.000 26.14071 ? 153 GLN B NE2 1 
ATOM   2780 N N   . PRO B 1 155 ? 40.63458 57.78340 66.30735  1.000 24.83086 ? 154 PRO B N   1 
ATOM   2781 C CA  . PRO B 1 155 ? 40.69440 59.23579 66.55805  1.000 22.32518 ? 154 PRO B CA  1 
ATOM   2782 C C   . PRO B 1 155 ? 40.30842 60.00450 65.30830  1.000 27.02584 ? 154 PRO B C   1 
ATOM   2783 O O   . PRO B 1 155 ? 40.92430 59.83961 64.25970  1.000 28.41777 ? 154 PRO B O   1 
ATOM   2784 C CB  . PRO B 1 155 ? 42.16605 59.48297 66.90134  1.000 24.16755 ? 154 PRO B CB  1 
ATOM   2785 C CG  . PRO B 1 155 ? 42.80308 58.11729 66.99527  1.000 34.10065 ? 154 PRO B CG  1 
ATOM   2786 C CD  . PRO B 1 155 ? 41.97134 57.19027 66.19201  1.000 28.16932 ? 154 PRO B CD  1 
ATOM   2787 N N   . ALA B 1 156 ? 39.35019 60.92360 65.45290  1.000 29.56209 ? 155 ALA B N   1 
ATOM   2788 C CA  . ALA B 1 156 ? 38.76804 61.61258 64.29626  1.000 22.80963 ? 155 ALA B CA  1 
ATOM   2789 C C   . ALA B 1 156 ? 39.80189 62.34997 63.45763  1.000 24.00006 ? 155 ALA B C   1 
ATOM   2790 O O   . ALA B 1 156 ? 39.59772 62.53287 62.25182  1.000 26.58649 ? 155 ALA B O   1 
ATOM   2791 C CB  . ALA B 1 156 ? 37.69596 62.60057 64.75215  1.000 25.43048 ? 155 ALA B CB  1 
ATOM   2792 N N   . SER B 1 157 ? 40.88548 62.81663 64.07255  1.000 22.12865 ? 156 SER B N   1 
ATOM   2793 C CA  . SER B 1 157 ? 41.77197 63.76634 63.42944  1.000 22.43765 ? 156 SER B CA  1 
ATOM   2794 C C   . SER B 1 157 ? 43.18330 63.56074 63.94528  1.000 23.78814 ? 156 SER B C   1 
ATOM   2795 O O   . SER B 1 157 ? 43.39426 63.28021 65.12483  1.000 23.93546 ? 156 SER B O   1 
ATOM   2796 C CB  . SER B 1 157 ? 41.33708 65.21263 63.72106  1.000 32.18108 ? 156 SER B CB  1 
ATOM   2797 O OG  . SER B 1 157 ? 40.00587 65.49840 63.29667  1.000 27.52074 ? 156 SER B OG  1 
ATOM   2798 N N   . ALA B 1 158 ? 44.14419 63.74073 63.05413  1.000 25.50424 ? 157 ALA B N   1 
ATOM   2799 C CA  . ALA B 1 158 ? 45.55395 63.63427 63.37750  1.000 22.59532 ? 157 ALA B CA  1 
ATOM   2800 C C   . ALA B 1 158 ? 46.29244 64.48380 62.35978  1.000 28.58280 ? 157 ALA B C   1 
ATOM   2801 O O   . ALA B 1 158 ? 45.78479 64.74450 61.26129  1.000 26.11926 ? 157 ALA B O   1 
ATOM   2802 C CB  . ALA B 1 158 ? 46.03752 62.18045 63.35063  1.000 24.83591 ? 157 ALA B CB  1 
ATOM   2803 N N   . SER B 1 159 ? 47.48837 64.92729 62.73817  1.000 26.18258 ? 158 SER B N   1 
ATOM   2804 C CA  . SER B 1 159 ? 48.21994 65.85642 61.89752  1.000 23.03451 ? 158 SER B CA  1 
ATOM   2805 C C   . SER B 1 159 ? 49.70463 65.72734 62.16558  1.000 23.50071 ? 158 SER B C   1 
ATOM   2806 O O   . SER B 1 159 ? 50.12751 65.14062 63.16419  1.000 26.69032 ? 158 SER B O   1 
ATOM   2807 C CB  . SER B 1 159 ? 47.77840 67.29363 62.14832  1.000 24.23472 ? 158 SER B CB  1 
ATOM   2808 O OG  . SER B 1 159 ? 48.36090 67.76940 63.34880  1.000 35.20619 ? 158 SER B OG  1 
ATOM   2809 N N   . GLY B 1 160 ? 50.48874 66.28621 61.25138  1.000 23.51996 ? 159 GLY B N   1 
ATOM   2810 C CA  . GLY B 1 160 ? 51.93357 66.29859 61.37115  1.000 24.59867 ? 159 GLY B CA  1 
ATOM   2811 C C   . GLY B 1 160 ? 52.51129 67.22334 60.32821  1.000 36.41989 ? 159 GLY B C   1 
ATOM   2812 O O   . GLY B 1 160 ? 51.78981 67.79324 59.50425  1.000 39.29837 ? 159 GLY B O   1 
ATOM   2813 N N   . SER B 1 161 ? 53.81551 67.43486 60.42285  1.000 37.46857 ? 160 SER B N   1 
ATOM   2814 C CA  . SER B 1 161 ? 54.52600 68.15806 59.37748  1.000 40.76053 ? 160 SER B CA  1 
ATOM   2815 C C   . SER B 1 161 ? 55.43402 67.20710 58.61994  1.000 35.94783 ? 160 SER B C   1 
ATOM   2816 O O   . SER B 1 161 ? 55.80741 66.14982 59.14012  1.000 41.83473 ? 160 SER B O   1 
ATOM   2817 C CB  . SER B 1 161 ? 55.35903 69.30775 59.94892  1.000 39.11917 ? 160 SER B CB  1 
ATOM   2818 O OG  . SER B 1 161 ? 54.51297 70.36648 60.33370  1.000 41.11146 ? 160 SER B OG  1 
ATOM   2819 N N   . PRO B 1 162 ? 55.77825 67.52272 57.37687  1.000 32.69738 ? 161 PRO B N   1 
ATOM   2820 C CA  . PRO B 1 162 ? 56.65801 66.62758 56.61258  1.000 38.25056 ? 161 PRO B CA  1 
ATOM   2821 C C   . PRO B 1 162 ? 57.90563 66.26193 57.40717  1.000 37.43157 ? 161 PRO B C   1 
ATOM   2822 O O   . PRO B 1 162 ? 58.57226 67.11705 57.99662  1.000 40.32272 ? 161 PRO B O   1 
ATOM   2823 C CB  . PRO B 1 162 ? 56.98532 67.44864 55.36595  1.000 40.24494 ? 161 PRO B CB  1 
ATOM   2824 C CG  . PRO B 1 162 ? 55.70842 68.24397 55.13885  1.000 34.12697 ? 161 PRO B CG  1 
ATOM   2825 C CD  . PRO B 1 162 ? 55.09708 68.50065 56.51108  1.000 36.15053 ? 161 PRO B CD  1 
ATOM   2826 N N   . GLY B 1 163 ? 58.19450 64.96657 57.45071  1.000 36.16895 ? 162 GLY B N   1 
ATOM   2827 C CA  . GLY B 1 163 ? 59.24986 64.42086 58.25607  1.000 31.84167 ? 162 GLY B CA  1 
ATOM   2828 C C   . GLY B 1 163 ? 58.80578 63.97681 59.63372  1.000 34.51296 ? 162 GLY B C   1 
ATOM   2829 O O   . GLY B 1 163 ? 59.35245 63.00989 60.16446  1.000 35.07050 ? 162 GLY B O   1 
ATOM   2830 N N   . GLN B 1 164 ? 57.82397 64.64945 60.22295  1.000 34.91665 ? 163 GLN B N   1 
ATOM   2831 C CA  . GLN B 1 164 ? 57.31697 64.22922 61.51944  1.000 32.04670 ? 163 GLN B CA  1 
ATOM   2832 C C   . GLN B 1 164 ? 56.57531 62.90319 61.42744  1.000 30.51745 ? 163 GLN B C   1 
ATOM   2833 O O   . GLN B 1 164 ? 56.19681 62.44221 60.34978  1.000 36.54224 ? 163 GLN B O   1 
ATOM   2834 C CB  . GLN B 1 164 ? 56.39330 65.29470 62.09416  1.000 31.47761 ? 163 GLN B CB  1 
ATOM   2835 C CG  . GLN B 1 164 ? 56.95661 66.67909 61.93736  1.000 36.87656 ? 163 GLN B CG  1 
ATOM   2836 C CD  . GLN B 1 164 ? 56.34368 67.67433 62.88009  1.000 35.05727 ? 163 GLN B CD  1 
ATOM   2837 O OE1 . GLN B 1 164 ? 55.12975 67.87166 62.88124  1.000 37.02927 ? 163 GLN B OE1 1 
ATOM   2838 N NE2 . GLN B 1 164 ? 57.18083 68.31447 63.69598  1.000 32.11507 ? 163 GLN B NE2 1 
ATOM   2839 N N   . SER B 1 165 ? 56.36315 62.29433 62.58864  1.000 31.80884 ? 164 SER B N   1 
ATOM   2840 C CA  . SER B 1 165 ? 55.55114 61.09497 62.71603  1.000 32.47352 ? 164 SER B CA  1 
ATOM   2841 C C   . SER B 1 165 ? 54.17469 61.40606 63.27424  1.000 28.35327 ? 164 SER B C   1 
ATOM   2842 O O   . SER B 1 165 ? 53.90560 62.47964 63.82299  1.000 32.73264 ? 164 SER B O   1 
ATOM   2843 C CB  . SER B 1 165 ? 56.21560 60.06535 63.62690  1.000 32.94538 ? 164 SER B CB  1 
ATOM   2844 O OG  . SER B 1 165 ? 57.32517 59.48243 62.99122  1.000 44.82244 ? 164 SER B OG  1 
ATOM   2845 N N   . VAL B 1 166 ? 53.31241 60.40521 63.16049  1.000 23.28208 ? 165 VAL B N   1 
ATOM   2846 C CA  . VAL B 1 166 ? 51.97696 60.43529 63.72900  1.000 27.70029 ? 165 VAL B CA  1 
ATOM   2847 C C   . VAL B 1 166 ? 51.59113 58.98809 64.01716  1.000 31.16619 ? 165 VAL B C   1 
ATOM   2848 O O   . VAL B 1 166 ? 52.06459 58.05377 63.36239  1.000 29.19978 ? 165 VAL B O   1 
ATOM   2849 C CB  . VAL B 1 166 ? 50.95629 61.13707 62.79544  1.000 21.77271 ? 165 VAL B CB  1 
ATOM   2850 C CG1 . VAL B 1 166 ? 50.64005 60.27984 61.60238  1.000 21.44788 ? 165 VAL B CG1 1 
ATOM   2851 C CG2 . VAL B 1 166 ? 49.68372 61.44478 63.52770  1.000 22.52459 ? 165 VAL B CG2 1 
ATOM   2852 N N   . THR B 1 167 ? 50.74239 58.79244 65.01232  1.000 27.90688 ? 166 THR B N   1 
ATOM   2853 C CA  . THR B 1 167 ? 50.25153 57.45497 65.27156  1.000 30.31284 ? 166 THR B CA  1 
ATOM   2854 C C   . THR B 1 167 ? 48.74465 57.52367 65.41884  1.000 27.76910 ? 166 THR B C   1 
ATOM   2855 O O   . THR B 1 167 ? 48.22019 58.38601 66.13447  1.000 29.30846 ? 166 THR B O   1 
ATOM   2856 C CB  . THR B 1 167 ? 50.90715 56.83112 66.51701  1.000 29.22023 ? 166 THR B CB  1 
ATOM   2857 O OG1 . THR B 1 167 ? 52.30700 56.65832 66.26973  1.000 35.18915 ? 166 THR B OG1 1 
ATOM   2858 C CG2 . THR B 1 167 ? 50.31806 55.46243 66.81234  1.000 20.23760 ? 166 THR B CG2 1 
ATOM   2859 N N   . ILE B 1 168 ? 48.06234 56.62765 64.71073  1.000 24.48497 ? 167 ILE B N   1 
ATOM   2860 C CA  . ILE B 1 168 ? 46.61568 56.49505 64.75575  1.000 28.34125 ? 167 ILE B CA  1 
ATOM   2861 C C   . ILE B 1 168 ? 46.28802 55.15989 65.39777  1.000 29.54684 ? 167 ILE B C   1 
ATOM   2862 O O   . ILE B 1 168 ? 46.85177 54.13102 65.01095  1.000 29.98726 ? 167 ILE B O   1 
ATOM   2863 C CB  . ILE B 1 168 ? 45.99995 56.60985 63.35191  1.000 27.79162 ? 167 ILE B CB  1 
ATOM   2864 C CG1 . ILE B 1 168 ? 46.08681 58.05180 62.86343  1.000 34.09328 ? 167 ILE B CG1 1 
ATOM   2865 C CG2 . ILE B 1 168 ? 44.60092 56.04266 63.34168  1.000 31.51056 ? 167 ILE B CG2 1 
ATOM   2866 C CD1 . ILE B 1 168 ? 47.39271 58.39153 62.17937  1.000 38.88694 ? 167 ILE B CD1 1 
ATOM   2867 N N   . THR B 1 169 ? 45.34889 55.17861 66.34530  1.000 27.53061 ? 168 THR B N   1 
ATOM   2868 C CA  . THR B 1 169 ? 44.94571 54.01223 67.11459  1.000 30.39566 ? 168 THR B CA  1 
ATOM   2869 C C   . THR B 1 169 ? 43.57288 53.50205 66.68616  1.000 34.20361 ? 168 THR B C   1 
ATOM   2870 O O   . THR B 1 169 ? 42.70041 54.25814 66.24633  1.000 32.71654 ? 168 THR B O   1 
ATOM   2871 C CB  . THR B 1 169 ? 44.93712 54.30478 68.61871  1.000 28.96307 ? 168 THR B CB  1 
ATOM   2872 O OG1 . THR B 1 169 ? 43.82436 55.14718 68.93402  1.000 31.78996 ? 168 THR B OG1 1 
ATOM   2873 C CG2 . THR B 1 169 ? 46.24221 54.98186 69.04748  1.000 28.94518 ? 168 THR B CG2 1 
ATOM   2874 N N   . CYS B 1 170 ? 43.39008 52.20004 66.86910  1.000 40.66227 ? 169 CYS B N   1 
ATOM   2875 C CA  . CYS B 1 170 ? 42.16927 51.49114 66.50227  1.000 42.26040 ? 169 CYS B CA  1 
ATOM   2876 C C   . CYS B 1 170 ? 41.85738 50.54645 67.64854  1.000 37.66973 ? 169 CYS B C   1 
ATOM   2877 O O   . CYS B 1 170 ? 42.53573 49.52954 67.81658  1.000 39.51812 ? 169 CYS B O   1 
ATOM   2878 C CB  . CYS B 1 170 ? 42.35558 50.72065 65.19351  1.000 38.94485 ? 169 CYS B CB  1 
ATOM   2879 S SG  . CYS B 1 170 ? 40.91215 49.82438 64.62544  1.000 42.11019 ? 169 CYS B SG  1 
ATOM   2880 N N   . THR B 1 171 ? 40.83821 50.87925 68.42602  1.000 33.02154 ? 170 THR B N   1 
ATOM   2881 C CA  . THR B 1 171 ? 40.50109 50.15045 69.63722  1.000 35.92749 ? 170 THR B CA  1 
ATOM   2882 C C   . THR B 1 171 ? 39.26904 49.30229 69.38155  1.000 36.76673 ? 170 THR B C   1 
ATOM   2883 O O   . THR B 1 171 ? 38.20383 49.83566 69.04841  1.000 34.02480 ? 170 THR B O   1 
ATOM   2884 C CB  . THR B 1 171 ? 40.24707 51.11293 70.79584  1.000 34.12796 ? 170 THR B CB  1 
ATOM   2885 O OG1 . THR B 1 171 ? 41.49937 51.62809 71.26518  1.000 42.46040 ? 170 THR B OG1 1 
ATOM   2886 C CG2 . THR B 1 171 ? 39.51141 50.41403 71.92261  1.000 26.71582 ? 170 THR B CG2 1 
ATOM   2887 N N   . GLY B 1 172 ? 39.42020 47.98645 69.53780  1.000 36.60162 ? 171 GLY B N   1 
ATOM   2888 C CA  . GLY B 1 172 ? 38.29963 47.08275 69.40484  1.000 29.71941 ? 171 GLY B CA  1 
ATOM   2889 C C   . GLY B 1 172 ? 38.06250 46.30657 70.67378  1.000 34.82565 ? 171 GLY B C   1 
ATOM   2890 O O   . GLY B 1 172 ? 38.20557 46.85137 71.77090  1.000 38.01296 ? 171 GLY B O   1 
ATOM   2891 N N   . SER B 1 173 ? 37.77013 45.01647 70.53905  1.000 42.30993 ? 172 SER B N   1 
ATOM   2892 C CA  . SER B 1 173 ? 37.39429 44.17460 71.66616  1.000 37.01148 ? 172 SER B CA  1 
ATOM   2893 C C   . SER B 1 173 ? 38.14488 42.85212 71.58475  1.000 39.11065 ? 172 SER B C   1 
ATOM   2894 O O   . SER B 1 173 ? 39.13625 42.70421 70.85845  1.000 36.08615 ? 172 SER B O   1 
ATOM   2895 C CB  . SER B 1 173 ? 35.88240 43.93820 71.66334  1.000 34.28875 ? 172 SER B CB  1 
ATOM   2896 O OG  . SER B 1 173 ? 35.54351 43.01364 70.64457  1.000 40.75374 ? 172 SER B OG  1 
ATOM   2897 N N   . SER B 1 174 ? 37.70104 41.89736 72.39740  1.000 35.33448 ? 173 SER B N   1 
ATOM   2898 C CA  . SER B 1 174 ? 38.18112 40.53678 72.22092  1.000 37.45661 ? 173 SER B CA  1 
ATOM   2899 C C   . SER B 1 174 ? 37.65859 39.91882 70.91753  1.000 37.60990 ? 173 SER B C   1 
ATOM   2900 O O   . SER B 1 174 ? 38.38674 39.17149 70.25246  1.000 32.48573 ? 173 SER B O   1 
ATOM   2901 C CB  . SER B 1 174 ? 37.82665 39.71046 73.45642  1.000 32.23334 ? 173 SER B CB  1 
ATOM   2902 O OG  . SER B 1 174 ? 36.43604 39.72325 73.71666  1.000 41.83059 ? 173 SER B OG  1 
ATOM   2903 N N   . SER B 1 175 ? 36.44209 40.26818 70.48543  1.000 36.61069 ? 174 SER B N   1 
ATOM   2904 C CA  . SER B 1 175 ? 35.91911 39.60723 69.28430  1.000 40.87630 ? 174 SER B CA  1 
ATOM   2905 C C   . SER B 1 175 ? 36.56071 40.08858 67.98945  1.000 41.53585 ? 174 SER B C   1 
ATOM   2906 O O   . SER B 1 175 ? 36.19230 39.57328 66.92635  1.000 41.68345 ? 174 SER B O   1 
ATOM   2907 C CB  . SER B 1 175 ? 34.40613 39.80864 69.15788  1.000 34.87593 ? 174 SER B CB  1 
ATOM   2908 O OG  . SER B 1 175 ? 33.71846 39.36538 70.30864  1.000 38.53327 ? 174 SER B OG  1 
ATOM   2909 N N   . ASP B 1 176 ? 37.46503 41.06817 68.03029  1.000 36.61659 ? 175 ASP B N   1 
ATOM   2910 C CA  . ASP B 1 176 ? 37.99971 41.62199 66.79561  1.000 29.30269 ? 175 ASP B CA  1 
ATOM   2911 C C   . ASP B 1 176 ? 39.49353 41.88904 66.91902  1.000 30.79603 ? 175 ASP B C   1 
ATOM   2912 O O   . ASP B 1 176 ? 40.29014 40.94735 66.84528  1.000 32.16786 ? 175 ASP B O   1 
ATOM   2913 C CB  . ASP B 1 176 ? 37.20450 42.87425 66.38953  1.000 36.10555 ? 175 ASP B CB  1 
ATOM   2914 C CG  . ASP B 1 176 ? 36.98658 43.85720 67.54672  1.000 41.12420 ? 175 ASP B CG  1 
ATOM   2915 O OD1 . ASP B 1 176 ? 37.97915 44.24448 68.20833  1.000 37.75046 ? 175 ASP B OD1 1 
ATOM   2916 O OD2 . ASP B 1 176 ? 35.81193 44.21669 67.81304  1.000 35.88548 ? 175 ASP B OD2 1 
ATOM   2917 N N   . VAL B 1 177 ? 39.87170 43.15017 67.16761  1.000 31.17401 ? 176 VAL B N   1 
ATOM   2918 C CA  . VAL B 1 177 ? 41.28074 43.55573 67.17399  1.000 27.02265 ? 176 VAL B CA  1 
ATOM   2919 C C   . VAL B 1 177 ? 42.09638 42.69449 68.12964  1.000 31.42496 ? 176 VAL B C   1 
ATOM   2920 O O   . VAL B 1 177 ? 43.20167 42.24150 67.79972  1.000 32.00290 ? 176 VAL B O   1 
ATOM   2921 C CB  . VAL B 1 177 ? 41.40303 45.04829 67.53310  1.000 30.52794 ? 176 VAL B CB  1 
ATOM   2922 C CG1 . VAL B 1 177 ? 42.81617 45.38019 67.96567  1.000 35.09037 ? 176 VAL B CG1 1 
ATOM   2923 C CG2 . VAL B 1 177 ? 41.01988 45.91611 66.34607  1.000 36.78740 ? 176 VAL B CG2 1 
ATOM   2924 N N   . GLY B 1 178 ? 41.58197 42.47580 69.33536  1.000 33.06154 ? 177 GLY B N   1 
ATOM   2925 C CA  . GLY B 1 178 ? 42.30987 41.66882 70.29092  1.000 33.03595 ? 177 GLY B CA  1 
ATOM   2926 C C   . GLY B 1 178 ? 42.05264 40.17751 70.19800  1.000 41.07665 ? 177 GLY B C   1 
ATOM   2927 O O   . GLY B 1 178 ? 42.58301 39.41505 71.01271  1.000 35.42398 ? 177 GLY B O   1 
ATOM   2928 N N   . GLY B 1 179 ? 41.26934 39.72253 69.22172  1.000 32.57033 ? 178 GLY B N   1 
ATOM   2929 C CA  . GLY B 1 179 ? 40.96800 38.31362 69.16552  1.000 34.37089 ? 178 GLY B CA  1 
ATOM   2930 C C   . GLY B 1 179 ? 41.67624 37.56619 68.05821  1.000 36.57862 ? 178 GLY B C   1 
ATOM   2931 O O   . GLY B 1 179 ? 41.76743 36.33665 68.10012  1.000 38.48369 ? 178 GLY B O   1 
ATOM   2932 N N   . TYR B 1 180 ? 42.20912 38.29104 67.08278  1.000 33.85414 ? 179 TYR B N   1 
ATOM   2933 C CA  . TYR B 1 180 ? 42.83704 37.68310 65.92575  1.000 30.62460 ? 179 TYR B CA  1 
ATOM   2934 C C   . TYR B 1 180 ? 44.04697 38.51203 65.56604  1.000 30.08310 ? 179 TYR B C   1 
ATOM   2935 O O   . TYR B 1 180 ? 44.27686 39.58994 66.12315  1.000 30.92463 ? 179 TYR B O   1 
ATOM   2936 C CB  . TYR B 1 180 ? 41.90359 37.60288 64.72254  1.000 28.47901 ? 179 TYR B CB  1 
ATOM   2937 C CG  . TYR B 1 180 ? 40.60039 36.98134 65.04429  1.000 28.20443 ? 179 TYR B CG  1 
ATOM   2938 C CD1 . TYR B 1 180 ? 40.42997 35.62213 64.93470  1.000 27.29625 ? 179 TYR B CD1 1 
ATOM   2939 C CD2 . TYR B 1 180 ? 39.53212 37.75160 65.46741  1.000 31.20053 ? 179 TYR B CD2 1 
ATOM   2940 C CE1 . TYR B 1 180 ? 39.22863 35.03586 65.22935  1.000 24.89894 ? 179 TYR B CE1 1 
ATOM   2941 C CE2 . TYR B 1 180 ? 38.32508 37.17079 65.77682  1.000 33.34092 ? 179 TYR B CE2 1 
ATOM   2942 C CZ  . TYR B 1 180 ? 38.18566 35.80581 65.65073  1.000 30.48577 ? 179 TYR B CZ  1 
ATOM   2943 O OH  . TYR B 1 180 ? 36.99256 35.20392 65.94933  1.000 38.72668 ? 179 TYR B OH  1 
ATOM   2944 N N   . LYS B 1 181 ? 44.82745 37.98741 64.63180  1.000 26.88527 ? 180 LYS B N   1 
ATOM   2945 C CA  . LYS B 1 181 ? 45.96286 38.70519 64.08658  1.000 31.83610 ? 180 LYS B CA  1 
ATOM   2946 C C   . LYS B 1 181 ? 45.65862 39.08535 62.63116  1.000 29.15096 ? 180 LYS B C   1 
ATOM   2947 O O   . LYS B 1 181 ? 46.48900 38.95741 61.72756  1.000 22.29985 ? 180 LYS B O   1 
ATOM   2948 C CB  . LYS B 1 181 ? 47.24629 37.89027 64.26947  1.000 30.40858 ? 180 LYS B CB  1 
ATOM   2949 C CG  . LYS B 1 181 ? 48.49174 38.69851 63.99755  1.000 38.97203 ? 180 LYS B CG  1 
ATOM   2950 C CD  . LYS B 1 181 ? 49.78828 38.00000 64.33507  1.000 40.63677 ? 180 LYS B CD  1 
ATOM   2951 C CE  . LYS B 1 181 ? 50.96785 38.87715 63.96848  1.000 27.51345 ? 180 LYS B CE  1 
ATOM   2952 N NZ  . LYS B 1 181 ? 51.05369 38.92542 62.45744  1.000 24.32324 ? 180 LYS B NZ  1 
ATOM   2953 N N   . TYR B 1 182 ? 44.42667 39.54137 62.39541  1.000 26.88971 ? 181 TYR B N   1 
ATOM   2954 C CA  . TYR B 1 182 ? 44.00629 40.04458 61.08963  1.000 29.04230 ? 181 TYR B CA  1 
ATOM   2955 C C   . TYR B 1 182 ? 43.42364 41.44732 61.26091  1.000 29.71005 ? 181 TYR B C   1 
ATOM   2956 O O   . TYR B 1 182 ? 42.20596 41.62470 61.19189  1.000 26.76712 ? 181 TYR B O   1 
ATOM   2957 C CB  . TYR B 1 182 ? 43.01076 39.13268 60.42819  1.000 30.23588 ? 181 TYR B CB  1 
ATOM   2958 C CG  . TYR B 1 182 ? 43.37653 37.67965 60.43880  1.000 33.36998 ? 181 TYR B CG  1 
ATOM   2959 C CD1 . TYR B 1 182 ? 42.56317 36.76218 61.06706  1.000 29.37369 ? 181 TYR B CD1 1 
ATOM   2960 C CD2 . TYR B 1 182 ? 44.52657 37.22564 59.81412  1.000 30.68593 ? 181 TYR B CD2 1 
ATOM   2961 C CE1 . TYR B 1 182 ? 42.87455 35.44376 61.07246  1.000 37.62459 ? 181 TYR B CE1 1 
ATOM   2962 C CE2 . TYR B 1 182 ? 44.85270 35.89610 59.81601  1.000 34.80259 ? 181 TYR B CE2 1 
ATOM   2963 C CZ  . TYR B 1 182 ? 44.02167 35.00867 60.45342  1.000 39.70153 ? 181 TYR B CZ  1 
ATOM   2964 O OH  . TYR B 1 182 ? 44.32287 33.66989 60.48727  1.000 53.67554 ? 181 TYR B OH  1 
ATOM   2965 N N   . VAL B 1 183 ? 44.29884 42.43460 61.46130  1.000 25.81650 ? 182 VAL B N   1 
ATOM   2966 C CA  . VAL B 1 183 ? 43.92587 43.84575 61.46693  1.000 26.67472 ? 182 VAL B CA  1 
ATOM   2967 C C   . VAL B 1 183 ? 44.60171 44.50976 60.27180  1.000 25.02633 ? 182 VAL B C   1 
ATOM   2968 O O   . VAL B 1 183 ? 45.83070 44.44591 60.13233  1.000 23.60901 ? 182 VAL B O   1 
ATOM   2969 C CB  . VAL B 1 183 ? 44.31650 44.55368 62.78277  1.000 26.35119 ? 182 VAL B CB  1 
ATOM   2970 C CG1 . VAL B 1 183 ? 44.37914 46.06094 62.56123  1.000 23.61454 ? 182 VAL B CG1 1 
ATOM   2971 C CG2 . VAL B 1 183 ? 43.33293 44.26190 63.89783  1.000 22.48550 ? 182 VAL B CG2 1 
ATOM   2972 N N   . SER B 1 184 ? 43.80228 45.15873 59.42151  1.000 25.51215 ? 183 SER B N   1 
ATOM   2973 C CA  . SER B 1 184 ? 44.28833 45.87753 58.25164  1.000 23.42943 ? 183 SER B CA  1 
ATOM   2974 C C   . SER B 1 184 ? 44.09552 47.38113 58.40106  1.000 25.18021 ? 183 SER B C   1 
ATOM   2975 O O   . SER B 1 184 ? 43.22763 47.85590 59.14447  1.000 26.09266 ? 183 SER B O   1 
ATOM   2976 C CB  . SER B 1 184 ? 43.57547 45.40004 56.99068  1.000 22.87652 ? 183 SER B CB  1 
ATOM   2977 O OG  . SER B 1 184 ? 43.67368 44.00264 56.87041  1.000 27.28734 ? 183 SER B OG  1 
ATOM   2978 N N   . TRP B 1 185 ? 44.88545 48.13283 57.63544  1.000 24.43327 ? 184 TRP B N   1 
ATOM   2979 C CA  . TRP B 1 185 ? 44.74503 49.58432 57.55469  1.000 23.54607 ? 184 TRP B CA  1 
ATOM   2980 C C   . TRP B 1 185 ? 44.65854 49.99922 56.09794  1.000 23.48380 ? 184 TRP B C   1 
ATOM   2981 O O   . TRP B 1 185 ? 45.51305 49.62635 55.28587  1.000 22.62920 ? 184 TRP B O   1 
ATOM   2982 C CB  . TRP B 1 185 ? 45.92397 50.31931 58.20332  1.000 22.87949 ? 184 TRP B CB  1 
ATOM   2983 C CG  . TRP B 1 185 ? 46.10080 50.09225 59.67605  1.000 28.96632 ? 184 TRP B CG  1 
ATOM   2984 C CD1 . TRP B 1 185 ? 46.77994 49.05978 60.29028  1.000 23.27232 ? 184 TRP B CD1 1 
ATOM   2985 C CD2 . TRP B 1 185 ? 45.63621 50.94411 60.72555  1.000 29.01546 ? 184 TRP B CD2 1 
ATOM   2986 N NE1 . TRP B 1 185 ? 46.75418 49.22770 61.65143  1.000 19.59155 ? 184 TRP B NE1 1 
ATOM   2987 C CE2 . TRP B 1 185 ? 46.05500 50.36974 61.94657  1.000 26.52769 ? 184 TRP B CE2 1 
ATOM   2988 C CE3 . TRP B 1 185 ? 44.91679 52.14661 60.75225  1.000 22.59532 ? 184 TRP B CE3 1 
ATOM   2989 C CZ2 . TRP B 1 185 ? 45.75721 50.94939 63.17870  1.000 32.58654 ? 184 TRP B CZ2 1 
ATOM   2990 C CZ3 . TRP B 1 185 ? 44.62299 52.71242 61.96241  1.000 23.18021 ? 184 TRP B CZ3 1 
ATOM   2991 C CH2 . TRP B 1 185 ? 45.03958 52.11551 63.16579  1.000 30.98408 ? 184 TRP B CH2 1 
ATOM   2992 N N   . TYR B 1 186 ? 43.64688 50.79472 55.78572  1.000 24.20636 ? 185 TYR B N   1 
ATOM   2993 C CA  . TYR B 1 186 ? 43.43465 51.33238 54.45565  1.000 25.39734 ? 185 TYR B CA  1 
ATOM   2994 C C   . TYR B 1 186 ? 43.68035 52.83136 54.43580  1.000 28.33280 ? 185 TYR B C   1 
ATOM   2995 O O   . TYR B 1 186 ? 43.40930 53.54229 55.40681  1.000 27.55279 ? 185 TYR B O   1 
ATOM   2996 C CB  . TYR B 1 186 ? 42.01277 51.04830 53.96971  1.000 22.20758 ? 185 TYR B CB  1 
ATOM   2997 C CG  . TYR B 1 186 ? 41.84907 49.61280 53.60335  1.000 23.81458 ? 185 TYR B CG  1 
ATOM   2998 C CD1 . TYR B 1 186 ? 41.31793 48.71787 54.50381  1.000 26.12324 ? 185 TYR B CD1 1 
ATOM   2999 C CD2 . TYR B 1 186 ? 42.27326 49.13824 52.37280  1.000 25.89257 ? 185 TYR B CD2 1 
ATOM   3000 C CE1 . TYR B 1 186 ? 41.19376 47.39877 54.18732  1.000 30.27756 ? 185 TYR B CE1 1 
ATOM   3001 C CE2 . TYR B 1 186 ? 42.15303 47.81946 52.04905  1.000 25.61072 ? 185 TYR B CE2 1 
ATOM   3002 C CZ  . TYR B 1 186 ? 41.60994 46.95407 52.96038  1.000 27.27017 ? 185 TYR B CZ  1 
ATOM   3003 O OH  . TYR B 1 186 ? 41.47971 45.62243 52.66714  1.000 37.36056 ? 185 TYR B OH  1 
ATOM   3004 N N   . GLN B 1 187 ? 44.17532 53.29574 53.30116  1.000 22.33362 ? 186 GLN B N   1 
ATOM   3005 C CA  . GLN B 1 187 ? 44.32980 54.70478 53.00332  1.000 23.45929 ? 186 GLN B CA  1 
ATOM   3006 C C   . GLN B 1 187 ? 43.29501 55.04488 51.93976  1.000 20.04311 ? 186 GLN B C   1 
ATOM   3007 O O   . GLN B 1 187 ? 43.10460 54.27947 50.99705  1.000 24.75684 ? 186 GLN B O   1 
ATOM   3008 C CB  . GLN B 1 187 ? 45.75824 54.97630 52.52424  1.000 23.31955 ? 186 GLN B CB  1 
ATOM   3009 C CG  . GLN B 1 187 ? 46.12413 56.41047 52.21111  1.000 21.83459 ? 186 GLN B CG  1 
ATOM   3010 C CD  . GLN B 1 187 ? 47.33754 56.47645 51.29009  1.000 28.07527 ? 186 GLN B CD  1 
ATOM   3011 O OE1 . GLN B 1 187 ? 47.23172 56.18249 50.10106  1.000 29.49751 ? 186 GLN B OE1 1 
ATOM   3012 N NE2 . GLN B 1 187 ? 48.49848 56.83103 51.83939  1.000 24.87410 ? 186 GLN B NE2 1 
ATOM   3013 N N   . HIS B 1 188 ? 42.56595 56.12984 52.12816  1.000 18.28819 ? 187 HIS B N   1 
ATOM   3014 C CA  . HIS B 1 188 ? 41.51711 56.50513 51.18889  1.000 22.45489 ? 187 HIS B CA  1 
ATOM   3015 C C   . HIS B 1 188 ? 41.76174 57.94385 50.76818  1.000 29.50757 ? 187 HIS B C   1 
ATOM   3016 O O   . HIS B 1 188 ? 41.79711 58.85176 51.60608  1.000 29.17815 ? 187 HIS B O   1 
ATOM   3017 C CB  . HIS B 1 188 ? 40.11465 56.35391 51.78042  1.000 19.94219 ? 187 HIS B CB  1 
ATOM   3018 C CG  . HIS B 1 188 ? 39.01967 56.83319 50.87411  1.000 28.92709 ? 187 HIS B CG  1 
ATOM   3019 N ND1 . HIS B 1 188 ? 39.01464 56.59724 49.51624  1.000 32.79386 ? 187 HIS B ND1 1 
ATOM   3020 C CD2 . HIS B 1 188 ? 37.89154 57.54016 51.13203  1.000 35.56178 ? 187 HIS B CD2 1 
ATOM   3021 C CE1 . HIS B 1 188 ? 37.93411 57.13771 48.97651  1.000 29.73175 ? 187 HIS B CE1 1 
ATOM   3022 N NE2 . HIS B 1 188 ? 37.23227 57.70945 49.93595  1.000 29.95016 ? 187 HIS B NE2 1 
ATOM   3023 N N   . HIS B 1 189 ? 41.93748 58.13568 49.53953  1.000 30.87670 ? 188 HIS B N   1 
ATOM   3024 C CA  . HIS B 1 189 ? 41.92599 59.50020 49.06093  1.000 31.60296 ? 188 HIS B CA  1 
ATOM   3025 C C   . HIS B 1 189 ? 40.55551 59.76345 48.45613  1.000 33.18153 ? 188 HIS B C   1 
ATOM   3026 O O   . HIS B 1 189 ? 40.08539 58.94355 47.64441  1.000 33.82502 ? 188 HIS B O   1 
ATOM   3027 C CB  . HIS B 1 189 ? 43.02758 59.69678 48.02585  1.000 25.54191 ? 188 HIS B CB  1 
ATOM   3028 C CG  . HIS B 1 189 ? 44.39008 59.85851 48.62728  1.000 27.46830 ? 188 HIS B CG  1 
ATOM   3029 N ND1 . HIS B 1 189 ? 45.44874 59.02944 48.32181  1.000 27.80453 ? 188 HIS B ND1 1 
ATOM   3030 C CD2 . HIS B 1 189 ? 44.86691 60.76131 49.51693  1.000 27.17074 ? 188 HIS B CD2 1 
ATOM   3031 C CE1 . HIS B 1 189 ? 46.52115 59.41619 48.98935  1.000 24.63050 ? 188 HIS B CE1 1 
ATOM   3032 N NE2 . HIS B 1 189 ? 46.19283 60.46293 49.72638  1.000 29.14743 ? 188 HIS B NE2 1 
ATOM   3033 N N   . PRO B 1 190 ? 39.86142 60.85556 48.85271  1.000 30.07139 ? 189 PRO B N   1 
ATOM   3034 C CA  . PRO B 1 190 ? 38.47980 61.06867 48.38502  1.000 26.16829 ? 189 PRO B CA  1 
ATOM   3035 C C   . PRO B 1 190 ? 38.36366 60.97628 46.88360  1.000 25.34368 ? 189 PRO B C   1 
ATOM   3036 O O   . PRO B 1 190 ? 38.98857 61.76070 46.16959  1.000 26.54672 ? 189 PRO B O   1 
ATOM   3037 C CB  . PRO B 1 190 ? 38.15417 62.47671 48.88787  1.000 29.14335 ? 189 PRO B CB  1 
ATOM   3038 C CG  . PRO B 1 190 ? 38.97626 62.60732 50.13175  1.000 30.43434 ? 189 PRO B CG  1 
ATOM   3039 C CD  . PRO B 1 190 ? 40.25666 61.82578 49.88682  1.000 31.66303 ? 189 PRO B CD  1 
ATOM   3040 N N   . GLY B 1 191 ? 37.56673 60.02511 46.39332  1.000 31.34598 ? 190 GLY B N   1 
ATOM   3041 C CA  . GLY B 1 191 ? 37.43210 59.81790 44.96594  1.000 29.76900 ? 190 GLY B CA  1 
ATOM   3042 C C   . GLY B 1 191 ? 38.33946 58.75474 44.38622  1.000 36.30136 ? 190 GLY B C   1 
ATOM   3043 O O   . GLY B 1 191 ? 38.34318 58.56686 43.16363  1.000 39.78311 ? 190 GLY B O   1 
ATOM   3044 N N   . LYS B 1 192 ? 39.17484 58.12317 45.20330  1.000 43.16318 ? 191 LYS B N   1 
ATOM   3045 C CA  . LYS B 1 192 ? 40.04032 57.05026 44.75140  1.000 33.47712 ? 191 LYS B CA  1 
ATOM   3046 C C   . LYS B 1 192 ? 39.69746 55.79057 45.54018  1.000 36.21399 ? 191 LYS B C   1 
ATOM   3047 O O   . LYS B 1 192 ? 39.13266 55.84903 46.63534  1.000 31.51525 ? 191 LYS B O   1 
ATOM   3048 C CB  . LYS B 1 192 ? 41.52274 57.41958 44.91902  1.000 31.18527 ? 191 LYS B CB  1 
ATOM   3049 C CG  . LYS B 1 192 ? 41.94403 58.68627 44.18743  1.000 22.37235 ? 191 LYS B CG  1 
ATOM   3050 N N   . ALA B 1 193 ? 40.06806 54.64691 44.98696  1.000 32.30663 ? 192 ALA B N   1 
ATOM   3051 C CA  . ALA B 1 193 ? 39.76456 53.39562 45.64496  1.000 27.88236 ? 192 ALA B CA  1 
ATOM   3052 C C   . ALA B 1 193 ? 40.67938 53.21880 46.85507  1.000 40.37792 ? 192 ALA B C   1 
ATOM   3053 O O   . ALA B 1 193 ? 41.88583 53.47379 46.76364  1.000 42.66039 ? 192 ALA B O   1 
ATOM   3054 C CB  . ALA B 1 193 ? 39.93008 52.23230 44.68189  1.000 41.25621 ? 192 ALA B CB  1 
ATOM   3055 N N   . PRO B 1 194 ? 40.14254 52.79376 47.99827  1.000 34.39987 ? 193 PRO B N   1 
ATOM   3056 C CA  . PRO B 1 194 ? 40.98994 52.62297 49.17527  1.000 23.79556 ? 193 PRO B CA  1 
ATOM   3057 C C   . PRO B 1 194 ? 42.09540 51.63858 48.87103  1.000 22.53773 ? 193 PRO B C   1 
ATOM   3058 O O   . PRO B 1 194 ? 41.95909 50.78897 47.99370  1.000 30.44322 ? 193 PRO B O   1 
ATOM   3059 C CB  . PRO B 1 194 ? 40.02404 52.09373 50.23702  1.000 22.88723 ? 193 PRO B CB  1 
ATOM   3060 C CG  . PRO B 1 194 ? 38.65526 52.19575 49.61679  1.000 29.69423 ? 193 PRO B CG  1 
ATOM   3061 C CD  . PRO B 1 194 ? 38.86686 52.08712 48.15977  1.000 27.29029 ? 193 PRO B CD  1 
ATOM   3062 N N   . LYS B 1 195 ? 43.21734 51.79651 49.56909  1.000 22.14617 ? 194 LYS B N   1 
ATOM   3063 C CA  . LYS B 1 195 ? 44.43761 51.05153 49.28884  1.000 20.34617 ? 194 LYS B CA  1 
ATOM   3064 C C   . LYS B 1 195 ? 44.93854 50.39545 50.56998  1.000 24.80174 ? 194 LYS B C   1 
ATOM   3065 O O   . LYS B 1 195 ? 45.04823 51.05437 51.60833  1.000 26.63962 ? 194 LYS B O   1 
ATOM   3066 C CB  . LYS B 1 195 ? 45.50135 51.96971 48.68532  1.000 19.43734 ? 194 LYS B CB  1 
ATOM   3067 C CG  . LYS B 1 195 ? 46.93587 51.58868 48.98665  1.000 24.74760 ? 194 LYS B CG  1 
ATOM   3068 C CD  . LYS B 1 195 ? 47.92182 52.37042 48.09711  1.000 16.86038 ? 194 LYS B CD  1 
ATOM   3069 N N   . LEU B 1 196 ? 45.21644 49.09292 50.50378  1.000 26.14374 ? 195 LEU B N   1 
ATOM   3070 C CA  . LEU B 1 196 ? 45.74621 48.37024 51.65500  1.000 24.60904 ? 195 LEU B CA  1 
ATOM   3071 C C   . LEU B 1 196 ? 47.16177 48.84192 51.98012  1.000 29.81900 ? 195 LEU B C   1 
ATOM   3072 O O   . LEU B 1 196 ? 48.08293 48.69586 51.16755  1.000 30.87566 ? 195 LEU B O   1 
ATOM   3073 C CB  . LEU B 1 196 ? 45.73028 46.87120 51.38492  1.000 24.40133 ? 195 LEU B CB  1 
ATOM   3074 C CG  . LEU B 1 196 ? 45.81966 45.93379 52.58719  1.000 26.76959 ? 195 LEU B CG  1 
ATOM   3075 C CD1 . LEU B 1 196 ? 44.79808 46.28198 53.66693  1.000 21.84724 ? 195 LEU B CD1 1 
ATOM   3076 C CD2 . LEU B 1 196 ? 45.64450 44.50467 52.11751  1.000 31.79663 ? 195 LEU B CD2 1 
ATOM   3077 N N   . MET B 1 197 ? 47.33906 49.38518 53.18012  1.000 28.18906 ? 196 MET B N   1 
ATOM   3078 C CA  . MET B 1 197 ? 48.64136 49.83828 53.64366  1.000 27.87744 ? 196 MET B CA  1 
ATOM   3079 C C   . MET B 1 197 ? 49.31314 48.85082 54.58745  1.000 28.74735 ? 196 MET B C   1 
ATOM   3080 O O   . MET B 1 197 ? 50.53416 48.65346 54.51603  1.000 27.06148 ? 196 MET B O   1 
ATOM   3081 C CB  . MET B 1 197 ? 48.49097 51.20014 54.32090  1.000 26.60409 ? 196 MET B CB  1 
ATOM   3082 C CG  . MET B 1 197 ? 47.85435 52.22092 53.41024  1.000 27.96667 ? 196 MET B CG  1 
ATOM   3083 S SD  . MET B 1 197 ? 48.87355 52.63385 51.97901  1.000 33.50160 ? 196 MET B SD  1 
ATOM   3084 C CE  . MET B 1 197 ? 50.49957 52.72099 52.73825  1.000 27.11471 ? 196 MET B CE  1 
ATOM   3085 N N   . ILE B 1 198 ? 48.54408 48.24290 55.48454  1.000 26.91343 ? 197 ILE B N   1 
ATOM   3086 C CA  . ILE B 1 198 ? 49.05478 47.26616 56.44007  1.000 27.12494 ? 197 ILE B CA  1 
ATOM   3087 C C   . ILE B 1 198 ? 48.05354 46.12521 56.52099  1.000 23.42775 ? 197 ILE B C   1 
ATOM   3088 O O   . ILE B 1 198 ? 46.84202 46.35405 56.47984  1.000 27.76081 ? 197 ILE B O   1 
ATOM   3089 C CB  . ILE B 1 198 ? 49.28550 47.89383 57.82485  1.000 23.32652 ? 197 ILE B CB  1 
ATOM   3090 C CG1 . ILE B 1 198 ? 50.35521 48.96214 57.72553  1.000 22.33604 ? 197 ILE B CG1 1 
ATOM   3091 C CG2 . ILE B 1 198 ? 49.72049 46.84826 58.79838  1.000 29.90231 ? 197 ILE B CG2 1 
ATOM   3092 C CD1 . ILE B 1 198 ? 51.66967 48.46167 57.37446  1.000 27.64590 ? 197 ILE B CD1 1 
ATOM   3093 N N   . TYR B 1 199 ? 48.54487 44.89430 56.60989  1.000 25.36003 ? 198 TYR B N   1 
ATOM   3094 C CA  . TYR B 1 199 ? 47.64397 43.75828 56.77129  1.000 28.16064 ? 198 TYR B CA  1 
ATOM   3095 C C   . TYR B 1 199 ? 48.22971 42.75301 57.75942  1.000 26.24008 ? 198 TYR B C   1 
ATOM   3096 O O   . TYR B 1 199 ? 49.43885 42.72044 57.99458  1.000 24.51171 ? 198 TYR B O   1 
ATOM   3097 C CB  . TYR B 1 199 ? 47.36861 43.09575 55.41679  1.000 20.56819 ? 198 TYR B CB  1 
ATOM   3098 C CG  . TYR B 1 199 ? 48.54408 42.33551 54.86108  1.000 26.58233 ? 198 TYR B CG  1 
ATOM   3099 C CD1 . TYR B 1 199 ? 48.67816 40.95645 55.07234  1.000 29.31262 ? 198 TYR B CD1 1 
ATOM   3100 C CD2 . TYR B 1 199 ? 49.53343 42.98960 54.12937  1.000 28.84773 ? 198 TYR B CD2 1 
ATOM   3101 C CE1 . TYR B 1 199 ? 49.76147 40.26031 54.56513  1.000 25.14564 ? 198 TYR B CE1 1 
ATOM   3102 C CE2 . TYR B 1 199 ? 50.62816 42.30346 53.62053  1.000 26.02700 ? 198 TYR B CE2 1 
ATOM   3103 C CZ  . TYR B 1 199 ? 50.73440 40.94510 53.84251  1.000 28.39627 ? 198 TYR B CZ  1 
ATOM   3104 O OH  . TYR B 1 199 ? 51.80999 40.26833 53.32745  1.000 26.66408 ? 198 TYR B OH  1 
ATOM   3105 N N   . GLU B 1 200 ? 47.35961 41.89141 58.29976  1.000 29.47794 ? 199 GLU B N   1 
ATOM   3106 C CA  . GLU B 1 200 ? 47.74602 40.93709 59.33962  1.000 25.99853 ? 199 GLU B CA  1 
ATOM   3107 C C   . GLU B 1 200 ? 48.57242 41.64482 60.40938  1.000 29.33349 ? 199 GLU B C   1 
ATOM   3108 O O   . GLU B 1 200 ? 49.73180 41.30903 60.66745  1.000 30.25812 ? 199 GLU B O   1 
ATOM   3109 C CB  . GLU B 1 200 ? 48.48963 39.73955 58.74771  1.000 30.57378 ? 199 GLU B CB  1 
ATOM   3110 C CG  . GLU B 1 200 ? 47.55195 38.72407 58.11732  1.000 28.52797 ? 199 GLU B CG  1 
ATOM   3111 C CD  . GLU B 1 200 ? 48.24552 37.77962 57.17885  1.000 28.67941 ? 199 GLU B CD  1 
ATOM   3112 O OE1 . GLU B 1 200 ? 49.49452 37.70562 57.24534  1.000 28.37742 ? 199 GLU B OE1 1 
ATOM   3113 O OE2 . GLU B 1 200 ? 47.53313 37.13213 56.37302  1.000 21.94073 ? 199 GLU B OE2 1 
ATOM   3114 N N   . VAL B 1 201 ? 47.98218 42.72049 60.93482  1.000 29.59786 ? 200 VAL B N   1 
ATOM   3115 C CA  . VAL B 1 201 ? 48.48476 43.56374 62.01202  1.000 24.40967 ? 200 VAL B CA  1 
ATOM   3116 C C   . VAL B 1 201 ? 49.62735 44.44024 61.54271  1.000 27.48759 ? 200 VAL B C   1 
ATOM   3117 O O   . VAL B 1 201 ? 49.57081 45.66672 61.66398  1.000 27.84001 ? 200 VAL B O   1 
ATOM   3118 C CB  . VAL B 1 201 ? 48.94539 42.74553 63.22717  1.000 26.80078 ? 200 VAL B CB  1 
ATOM   3119 C CG1 . VAL B 1 201 ? 49.60502 43.66715 64.22476  1.000 28.35396 ? 200 VAL B CG1 1 
ATOM   3120 C CG2 . VAL B 1 201 ? 47.77870 42.03748 63.86228  1.000 30.88959 ? 200 VAL B CG2 1 
ATOM   3121 N N   . SER B 1 202 ? 50.66076 43.82955 60.98349  1.000 27.68338 ? 201 SER B N   1 
ATOM   3122 C CA  . SER B 1 202 ? 51.89664 44.57370 60.79115  1.000 29.02508 ? 201 SER B CA  1 
ATOM   3123 C C   . SER B 1 202 ? 52.55959 44.37132 59.44535  1.000 24.81077 ? 201 SER B C   1 
ATOM   3124 O O   . SER B 1 202 ? 53.66119 44.88385 59.24998  1.000 29.88262 ? 201 SER B O   1 
ATOM   3125 C CB  . SER B 1 202 ? 52.89408 44.17817 61.87259  1.000 35.46121 ? 201 SER B CB  1 
ATOM   3126 O OG  . SER B 1 202 ? 53.06014 42.76185 61.88041  1.000 32.31475 ? 201 SER B OG  1 
ATOM   3127 N N   . LYS B 1 203 ? 51.94345 43.65353 58.51898  1.000 26.89946 ? 202 LYS B N   1 
ATOM   3128 C CA  . LYS B 1 203 ? 52.59230 43.31894 57.25856  1.000 28.27515 ? 202 LYS B CA  1 
ATOM   3129 C C   . LYS B 1 203 ? 52.30539 44.39339 56.22318  1.000 28.65017 ? 202 LYS B C   1 
ATOM   3130 O O   . LYS B 1 203 ? 51.21995 44.98445 56.21320  1.000 26.60835 ? 202 LYS B O   1 
ATOM   3131 C CB  . LYS B 1 203 ? 52.13454 41.95325 56.74587  1.000 22.16746 ? 202 LYS B CB  1 
ATOM   3132 C CG  . LYS B 1 203 ? 52.60852 40.79030 57.59626  1.000 25.13298 ? 202 LYS B CG  1 
ATOM   3133 C CD  . LYS B 1 203 ? 52.15523 39.43935 57.01995  1.000 33.92318 ? 202 LYS B CD  1 
ATOM   3134 C CE  . LYS B 1 203 ? 52.87661 38.26332 57.68223  1.000 30.55280 ? 202 LYS B CE  1 
ATOM   3135 N NZ  . LYS B 1 203 ? 54.37768 38.39439 57.55048  1.000 27.67492 ? 202 LYS B NZ  1 
ATOM   3136 N N   . ARG B 1 204 ? 53.33160 44.68701 55.37622  1.000 24.88406 ? 203 ARG B N   1 
ATOM   3137 C CA  . ARG B 1 204 ? 53.20530 45.63517 54.27436  1.000 29.35218 ? 203 ARG B CA  1 
ATOM   3138 C C   . ARG B 1 204 ? 53.09246 44.93121 52.93141  1.000 32.68027 ? 203 ARG B C   1 
ATOM   3139 O O   . ARG B 1 204 ? 53.90760 44.04551 52.61396  1.000 32.54828 ? 203 ARG B O   1 
ATOM   3140 C CB  . ARG B 1 204 ? 54.38926 46.59675 54.25195  1.000 28.94021 ? 203 ARG B CB  1 
ATOM   3141 C CG  . ARG B 1 204 ? 54.18075 47.77208 55.14017  1.000 25.23830 ? 203 ARG B CG  1 
ATOM   3142 C CD  . ARG B 1 204 ? 55.28622 48.75400 54.99441  1.000 36.05218 ? 203 ARG B CD  1 
ATOM   3143 N NE  . ARG B 1 204 ? 56.37437 48.41354 55.88650  1.000 36.62339 ? 203 ARG B NE  1 
ATOM   3144 C CZ  . ARG B 1 204 ? 57.50463 47.87806 55.46224  1.000 38.70566 ? 203 ARG B CZ  1 
ATOM   3145 N NH1 . ARG B 1 204 ? 57.67899 47.64751 54.15434  1.000 32.55194 ? 203 ARG B NH1 1 
ATOM   3146 N NH2 . ARG B 1 204 ? 58.45197 47.58699 56.34326  1.000 39.72312 ? 203 ARG B NH2 1 
ATOM   3147 N N   . PRO B 1 205 ? 52.07674 45.28618 52.14960  1.000 33.44403 ? 204 PRO B N   1 
ATOM   3148 C CA  . PRO B 1 205 ? 51.96996 44.79062 50.77253  1.000 27.27182 ? 204 PRO B CA  1 
ATOM   3149 C C   . PRO B 1 205 ? 53.15419 45.22835 49.92166  1.000 31.02954 ? 204 PRO B C   1 
ATOM   3150 O O   . PRO B 1 205 ? 54.03623 45.97749 50.35641  1.000 36.56783 ? 204 PRO B O   1 
ATOM   3151 C CB  . PRO B 1 205 ? 50.66163 45.41907 50.28048  1.000 23.20133 ? 204 PRO B CB  1 
ATOM   3152 C CG  . PRO B 1 205 ? 49.85655 45.57575 51.49533  1.000 23.53861 ? 204 PRO B CG  1 
ATOM   3153 C CD  . PRO B 1 205 ? 50.83268 45.93513 52.59371  1.000 29.89582 ? 204 PRO B CD  1 
ATOM   3154 N N   . SER B 1 206 ? 53.18811 44.70190 48.69284  1.000 31.61739 ? 205 SER B N   1 
ATOM   3155 C CA  . SER B 1 206 ? 54.23331 45.04941 47.73149  1.000 31.62725 ? 205 SER B CA  1 
ATOM   3156 C C   . SER B 1 206 ? 54.18675 46.53402 47.42935  1.000 28.42985 ? 205 SER B C   1 
ATOM   3157 O O   . SER B 1 206 ? 53.14285 47.05599 47.02560  1.000 32.91627 ? 205 SER B O   1 
ATOM   3158 C CB  . SER B 1 206 ? 54.04428 44.27968 46.42837  1.000 25.34825 ? 205 SER B CB  1 
ATOM   3159 O OG  . SER B 1 206 ? 54.03616 42.88935 46.63826  1.000 36.77981 ? 205 SER B OG  1 
ATOM   3160 N N   . GLY B 1 207 ? 55.29113 47.23038 47.66532  1.000 25.21188 ? 206 GLY B N   1 
ATOM   3161 C CA  . GLY B 1 207 ? 55.33081 48.61725 47.23903  1.000 35.40325 ? 206 GLY B CA  1 
ATOM   3162 C C   . GLY B 1 207 ? 54.67001 49.61686 48.16278  1.000 38.13943 ? 206 GLY B C   1 
ATOM   3163 O O   . GLY B 1 207 ? 54.34947 50.72602 47.72354  1.000 41.45978 ? 206 GLY B O   1 
ATOM   3164 N N   . VAL B 1 208 ? 54.42374 49.24712 49.41427  1.000 34.01223 ? 207 VAL B N   1 
ATOM   3165 C CA  . VAL B 1 208 ? 54.00103 50.17858 50.44783  1.000 30.11185 ? 207 VAL B CA  1 
ATOM   3166 C C   . VAL B 1 208 ? 55.26578 50.68514 51.11906  1.000 30.89320 ? 207 VAL B C   1 
ATOM   3167 O O   . VAL B 1 208 ? 56.12076 49.87452 51.49475  1.000 30.18214 ? 207 VAL B O   1 
ATOM   3168 C CB  . VAL B 1 208 ? 53.06566 49.51878 51.46813  1.000 32.55558 ? 207 VAL B CB  1 
ATOM   3169 C CG1 . VAL B 1 208 ? 53.06738 50.31650 52.77356  1.000 29.23870 ? 207 VAL B CG1 1 
ATOM   3170 C CG2 . VAL B 1 208 ? 51.67169 49.41998 50.90936  1.000 30.24906 ? 207 VAL B CG2 1 
ATOM   3171 N N   . PRO B 1 209 ? 55.44775 52.00002 51.24247  1.000 32.87266 ? 208 PRO B N   1 
ATOM   3172 C CA  . PRO B 1 209 ? 56.68501 52.51466 51.83022  1.000 30.67570 ? 208 PRO B CA  1 
ATOM   3173 C C   . PRO B 1 209 ? 56.87107 51.98204 53.23820  1.000 36.28401 ? 208 PRO B C   1 
ATOM   3174 O O   . PRO B 1 209 ? 55.91660 51.87220 54.01337  1.000 36.38368 ? 208 PRO B O   1 
ATOM   3175 C CB  . PRO B 1 209 ? 56.47433 54.03334 51.83259  1.000 37.07600 ? 208 PRO B CB  1 
ATOM   3176 C CG  . PRO B 1 209 ? 55.42073 54.28511 50.81290  1.000 30.99070 ? 208 PRO B CG  1 
ATOM   3177 C CD  . PRO B 1 209 ? 54.55625 53.07640 50.77046  1.000 28.53674 ? 208 PRO B CD  1 
ATOM   3178 N N   . ASP B 1 210 ? 58.10470 51.57102 53.53352  1.000 36.89037 ? 209 ASP B N   1 
ATOM   3179 C CA  . ASP B 1 210 ? 58.45667 51.06593 54.85762  1.000 38.99068 ? 209 ASP B CA  1 
ATOM   3180 C C   . ASP B 1 210 ? 58.23193 52.08795 55.98169  1.000 39.84487 ? 209 ASP B C   1 
ATOM   3181 O O   . ASP B 1 210 ? 58.45390 51.75994 57.15649  1.000 30.36168 ? 209 ASP B O   1 
ATOM   3182 C CB  . ASP B 1 210 ? 59.91573 50.60729 54.84614  1.000 39.34664 ? 209 ASP B CB  1 
ATOM   3183 C CG  . ASP B 1 210 ? 60.90350 51.76673 54.95345  1.000 48.36962 ? 209 ASP B CG  1 
ATOM   3184 O OD1 . ASP B 1 210 ? 62.06555 51.49317 55.32256  1.000 51.91680 ? 209 ASP B OD1 1 
ATOM   3185 O OD2 . ASP B 1 210 ? 60.53804 52.93840 54.66894  1.000 46.01630 ? 209 ASP B OD2 1 
ATOM   3186 N N   . ARG B 1 211 ? 57.84401 53.32515 55.65999  1.000 36.32471 ? 210 ARG B N   1 
ATOM   3187 C CA  . ARG B 1 211 ? 57.54618 54.27577 56.71773  1.000 34.60565 ? 210 ARG B CA  1 
ATOM   3188 C C   . ARG B 1 211 ? 56.16823 54.06904 57.34181  1.000 33.95016 ? 210 ARG B C   1 
ATOM   3189 O O   . ARG B 1 211 ? 55.90259 54.64040 58.40664  1.000 34.17738 ? 210 ARG B O   1 
ATOM   3190 C CB  . ARG B 1 211 ? 57.69335 55.70586 56.18722  1.000 34.88544 ? 210 ARG B CB  1 
ATOM   3191 C CG  . ARG B 1 211 ? 56.72703 56.10065 55.09770  1.000 31.96285 ? 210 ARG B CG  1 
ATOM   3192 C CD  . ARG B 1 211 ? 56.76412 57.61228 54.82944  1.000 30.50657 ? 210 ARG B CD  1 
ATOM   3193 N NE  . ARG B 1 211 ? 55.71171 58.00490 53.89731  1.000 29.38530 ? 210 ARG B NE  1 
ATOM   3194 C CZ  . ARG B 1 211 ? 55.79815 57.82776 52.58215  1.000 33.90470 ? 210 ARG B CZ  1 
ATOM   3195 N NH1 . ARG B 1 211 ? 56.88943 57.27142 52.06321  1.000 29.71734 ? 210 ARG B NH1 1 
ATOM   3196 N NH2 . ARG B 1 211 ? 54.79365 58.18697 51.78633  1.000 34.76822 ? 210 ARG B NH2 1 
ATOM   3197 N N   . PHE B 1 212 ? 55.31247 53.22869 56.75701  1.000 34.34675 ? 211 PHE B N   1 
ATOM   3198 C CA  . PHE B 1 212 ? 54.06611 52.81391 57.40606  1.000 30.35876 ? 211 PHE B CA  1 
ATOM   3199 C C   . PHE B 1 212 ? 54.32688 51.58366 58.26664  1.000 30.64607 ? 211 PHE B C   1 
ATOM   3200 O O   . PHE B 1 212 ? 54.92925 50.61062 57.80108  1.000 31.07015 ? 211 PHE B O   1 
ATOM   3201 C CB  . PHE B 1 212 ? 52.96653 52.48854 56.39200  1.000 22.98632 ? 211 PHE B CB  1 
ATOM   3202 C CG  . PHE B 1 212 ? 52.50598 53.65838 55.59494  1.000 23.48926 ? 211 PHE B CG  1 
ATOM   3203 C CD1 . PHE B 1 212 ? 53.30006 54.18892 54.59981  1.000 33.42642 ? 211 PHE B CD1 1 
ATOM   3204 C CD2 . PHE B 1 212 ? 51.26905 54.22279 55.82847  1.000 30.01550 ? 211 PHE B CD2 1 
ATOM   3205 C CE1 . PHE B 1 212 ? 52.86870 55.28188 53.85385  1.000 37.47349 ? 211 PHE B CE1 1 
ATOM   3206 C CE2 . PHE B 1 212 ? 50.82466 55.32214 55.10168  1.000 30.49883 ? 211 PHE B CE2 1 
ATOM   3207 C CZ  . PHE B 1 212 ? 51.62397 55.85236 54.11154  1.000 33.79422 ? 211 PHE B CZ  1 
ATOM   3208 N N   . SER B 1 213 ? 53.88646 51.63753 59.52351  1.000 32.69065 ? 212 SER B N   1 
ATOM   3209 C CA  . SER B 1 213 ? 54.16211 50.60365 60.51000  1.000 26.75895 ? 212 SER B CA  1 
ATOM   3210 C C   . SER B 1 213 ? 52.86066 50.18879 61.17343  1.000 32.01267 ? 212 SER B C   1 
ATOM   3211 O O   . SER B 1 213 ? 52.04464 51.03658 61.55472  1.000 32.41454 ? 212 SER B O   1 
ATOM   3212 C CB  . SER B 1 213 ? 55.13288 51.08766 61.56645  1.000 30.43727 ? 212 SER B CB  1 
ATOM   3213 O OG  . SER B 1 213 ? 56.31041 51.57632 60.95567  1.000 42.00500 ? 212 SER B OG  1 
ATOM   3214 N N   . GLY B 1 214 ? 52.69345 48.88541 61.35085  1.000 30.32810 ? 213 GLY B N   1 
ATOM   3215 C CA  . GLY B 1 214 ? 51.50198 48.32714 61.95313  1.000 27.12125 ? 213 GLY B CA  1 
ATOM   3216 C C   . GLY B 1 214 ? 51.88176 47.69193 63.27256  1.000 36.10589 ? 213 GLY B C   1 
ATOM   3217 O O   . GLY B 1 214 ? 52.99629 47.17987 63.43252  1.000 31.90283 ? 213 GLY B O   1 
ATOM   3218 N N   . SER B 1 215 ? 50.94995 47.72737 64.22052  1.000 32.88896 ? 214 SER B N   1 
ATOM   3219 C CA  . SER B 1 215 ? 51.23679 47.18502 65.53655  1.000 30.94484 ? 214 SER B CA  1 
ATOM   3220 C C   . SER B 1 215 ? 49.93339 46.99468 66.28516  1.000 32.86366 ? 214 SER B C   1 
ATOM   3221 O O   . SER B 1 215 ? 48.89871 47.55811 65.91896  1.000 34.22682 ? 214 SER B O   1 
ATOM   3222 C CB  . SER B 1 215 ? 52.16904 48.10509 66.32629  1.000 44.05878 ? 214 SER B CB  1 
ATOM   3223 O OG  . SER B 1 215 ? 52.49981 47.52666 67.57812  1.000 52.27111 ? 214 SER B OG  1 
ATOM   3224 N N   . LYS B 1 216 ? 50.00776 46.20126 67.35164  1.000 31.68833 ? 215 LYS B N   1 
ATOM   3225 C CA  . LYS B 1 216 ? 48.84031 45.79997 68.12283  1.000 32.03870 ? 215 LYS B CA  1 
ATOM   3226 C C   . LYS B 1 216 ? 49.29308 45.42913 69.51935  1.000 34.56079 ? 215 LYS B C   1 
ATOM   3227 O O   . LYS B 1 216 ? 50.41608 44.95334 69.71930  1.000 34.28998 ? 215 LYS B O   1 
ATOM   3228 C CB  . LYS B 1 216 ? 48.13399 44.60521 67.48356  1.000 34.26311 ? 215 LYS B CB  1 
ATOM   3229 C CG  . LYS B 1 216 ? 46.76072 44.26410 68.00326  1.000 30.69334 ? 215 LYS B CG  1 
ATOM   3230 C CD  . LYS B 1 216 ? 46.18714 43.18296 67.08354  1.000 31.47005 ? 215 LYS B CD  1 
ATOM   3231 C CE  . LYS B 1 216 ? 46.44163 41.78473 67.56908  1.000 26.84059 ? 215 LYS B CE  1 
ATOM   3232 N NZ  . LYS B 1 216 ? 45.40251 41.41399 68.55269  1.000 31.50212 ? 215 LYS B NZ  1 
ATOM   3233 N N   . SER B 1 217 ? 48.38876 45.62509 70.47379  1.000 37.08452 ? 216 SER B N   1 
ATOM   3234 C CA  . SER B 1 217 ? 48.60464 45.21310 71.85729  1.000 36.70477 ? 216 SER B CA  1 
ATOM   3235 C C   . SER B 1 217 ? 47.24225 45.20322 72.53042  1.000 37.45330 ? 216 SER B C   1 
ATOM   3236 O O   . SER B 1 217 ? 46.53877 46.21780 72.50330  1.000 35.52487 ? 216 SER B O   1 
ATOM   3237 C CB  . SER B 1 217 ? 49.56649 46.17107 72.56492  1.000 29.80128 ? 216 SER B CB  1 
ATOM   3238 O OG  . SER B 1 217 ? 50.05202 45.61447 73.76444  1.000 35.21969 ? 216 SER B OG  1 
ATOM   3239 N N   . GLY B 1 218 ? 46.86486 44.07640 73.11683  1.000 33.69633 ? 217 GLY B N   1 
ATOM   3240 C CA  . GLY B 1 218 ? 45.53657 43.98111 73.69485  1.000 28.46483 ? 217 GLY B CA  1 
ATOM   3241 C C   . GLY B 1 218 ? 44.46389 44.22735 72.65595  1.000 28.41885 ? 217 GLY B C   1 
ATOM   3242 O O   . GLY B 1 218 ? 44.51688 43.70514 71.53975  1.000 33.07997 ? 217 GLY B O   1 
ATOM   3243 N N   . ASN B 1 219 ? 43.48017 45.04749 73.00914  1.000 30.01191 ? 218 ASN B N   1 
ATOM   3244 C CA  . ASN B 1 219 ? 42.33142 45.28360 72.14688  1.000 37.48728 ? 218 ASN B CA  1 
ATOM   3245 C C   . ASN B 1 219 ? 42.47513 46.52972 71.27338  1.000 34.19581 ? 218 ASN B C   1 
ATOM   3246 O O   . ASN B 1 219 ? 41.46980 47.01394 70.72919  1.000 32.59661 ? 218 ASN B O   1 
ATOM   3247 C CB  . ASN B 1 219 ? 41.04662 45.37549 72.97683  1.000 41.51533 ? 218 ASN B CB  1 
ATOM   3248 C CG  . ASN B 1 219 ? 40.60293 44.02926 73.52737  1.000 39.75640 ? 218 ASN B CG  1 
ATOM   3249 O OD1 . ASN B 1 219 ? 41.09859 42.98375 73.11595  1.000 33.59934 ? 218 ASN B OD1 1 
ATOM   3250 N ND2 . ASN B 1 219 ? 39.63202 44.05308 74.43670  1.000 45.05716 ? 218 ASN B ND2 1 
ATOM   3251 N N   . MET B 1 220 ? 43.68978 47.05366 71.11345  1.000 27.30214 ? 219 MET B N   1 
ATOM   3252 C CA  . MET B 1 220 ? 43.87341 48.32869 70.43160  1.000 29.87036 ? 219 MET B CA  1 
ATOM   3253 C C   . MET B 1 220 ? 45.04487 48.20669 69.47717  1.000 28.90336 ? 219 MET B C   1 
ATOM   3254 O O   . MET B 1 220 ? 46.17959 47.96655 69.90543  1.000 29.81786 ? 219 MET B O   1 
ATOM   3255 C CB  . MET B 1 220 ? 44.11203 49.48491 71.42207  1.000 35.24301 ? 219 MET B CB  1 
ATOM   3256 C CG  . MET B 1 220 ? 44.52938 50.82499 70.74795  1.000 35.52315 ? 219 MET B CG  1 
ATOM   3257 S SD  . MET B 1 220 ? 45.44559 52.05468 71.73944  1.000 39.04373 ? 219 MET B SD  1 
ATOM   3258 C CE  . MET B 1 220 ? 47.09291 51.32815 71.84599  1.000 34.15420 ? 219 MET B CE  1 
ATOM   3259 N N   . ALA B 1 221 ? 44.76926 48.38478 68.19033  1.000 31.85714 ? 220 ALA B N   1 
ATOM   3260 C CA  . ALA B 1 221 ? 45.80999 48.40282 67.17517  1.000 36.71043 ? 220 ALA B CA  1 
ATOM   3261 C C   . ALA B 1 221 ? 46.16608 49.84296 66.83463  1.000 38.07163 ? 220 ALA B C   1 
ATOM   3262 O O   . ALA B 1 221 ? 45.32327 50.74026 66.90088  1.000 34.57963 ? 220 ALA B O   1 
ATOM   3263 C CB  . ALA B 1 221 ? 45.35566 47.66886 65.91052  1.000 28.72173 ? 220 ALA B CB  1 
ATOM   3264 N N   . SER B 1 222 ? 47.40700 50.04795 66.40984  1.000 31.70306 ? 221 SER B N   1 
ATOM   3265 C CA  . SER B 1 222 ? 47.85254 51.37954 66.06089  1.000 26.57494 ? 221 SER B CA  1 
ATOM   3266 C C   . SER B 1 222 ? 48.73346 51.31635 64.81354  1.000 36.09637 ? 221 SER B C   1 
ATOM   3267 O O   . SER B 1 222 ? 49.56955 50.41484 64.66090  1.000 36.18738 ? 221 SER B O   1 
ATOM   3268 C CB  . SER B 1 222 ? 48.55574 52.04848 67.25387  1.000 23.05087 ? 221 SER B CB  1 
ATOM   3269 O OG  . SER B 1 222 ? 49.85754 51.54813 67.46620  1.000 34.87163 ? 221 SER B OG  1 
ATOM   3270 N N   . LEU B 1 223 ? 48.52779 52.29318 63.92819  1.000 31.03570 ? 222 LEU B N   1 
ATOM   3271 C CA  . LEU B 1 223 ? 49.31252 52.50175 62.72243  1.000 26.30590 ? 222 LEU B CA  1 
ATOM   3272 C C   . LEU B 1 223 ? 50.21571 53.70174 62.93611  1.000 27.41790 ? 222 LEU B C   1 
ATOM   3273 O O   . LEU B 1 223 ? 49.82507 54.65714 63.60479  1.000 30.66055 ? 222 LEU B O   1 
ATOM   3274 C CB  . LEU B 1 223 ? 48.39599 52.77204 61.53256  1.000 23.74313 ? 222 LEU B CB  1 
ATOM   3275 C CG  . LEU B 1 223 ? 49.04604 53.24241 60.24487  1.000 21.68744 ? 222 LEU B CG  1 
ATOM   3276 C CD1 . LEU B 1 223 ? 49.83060 52.09711 59.66661  1.000 24.00547 ? 222 LEU B CD1 1 
ATOM   3277 C CD2 . LEU B 1 223 ? 47.99293 53.69992 59.28072  1.000 19.23639 ? 222 LEU B CD2 1 
ATOM   3278 N N   . THR B 1 224 ? 51.43520 53.64824 62.41359  1.000 27.62551 ? 223 THR B N   1 
ATOM   3279 C CA  . THR B 1 224 ? 52.32619 54.79474 62.53162  1.000 31.95556 ? 223 THR B CA  1 
ATOM   3280 C C   . THR B 1 224 ? 53.03079 55.05353 61.20973  1.000 32.88333 ? 223 THR B C   1 
ATOM   3281 O O   . THR B 1 224 ? 53.82304 54.22330 60.75198  1.000 29.79148 ? 223 THR B O   1 
ATOM   3282 C CB  . THR B 1 224 ? 53.35081 54.58848 63.64654  1.000 32.34076 ? 223 THR B CB  1 
ATOM   3283 O OG1 . THR B 1 224 ? 52.67953 54.60416 64.91184  1.000 32.62025 ? 223 THR B OG1 1 
ATOM   3284 C CG2 . THR B 1 224 ? 54.37770 55.70037 63.61254  1.000 28.26255 ? 223 THR B CG2 1 
ATOM   3285 N N   . VAL B 1 225 ? 52.79566 56.22489 60.62796  1.000 29.67508 ? 224 VAL B N   1 
ATOM   3286 C CA  . VAL B 1 225 ? 53.53523 56.64183 59.44794  1.000 37.35645 ? 224 VAL B CA  1 
ATOM   3287 C C   . VAL B 1 225 ? 54.66097 57.53094 59.95110  1.000 35.60861 ? 224 VAL B C   1 
ATOM   3288 O O   . VAL B 1 225 ? 54.46418 58.69973 60.27657  1.000 40.29049 ? 224 VAL B O   1 
ATOM   3289 C CB  . VAL B 1 225 ? 52.65344 57.32983 58.39749  1.000 37.54619 ? 224 VAL B CB  1 
ATOM   3290 C CG1 . VAL B 1 225 ? 51.84840 58.44960 58.97791  1.000 35.30838 ? 224 VAL B CG1 1 
ATOM   3291 C CG2 . VAL B 1 225 ? 53.52331 57.89853 57.29506  1.000 35.26565 ? 224 VAL B CG2 1 
ATOM   3292 N N   . SER B 1 226 ? 55.85317 56.96074 60.02871  1.000 35.19958 ? 225 SER B N   1 
ATOM   3293 C CA  . SER B 1 226 ? 57.02193 57.74860 60.35022  1.000 33.78096 ? 225 SER B CA  1 
ATOM   3294 C C   . SER B 1 226 ? 57.39766 58.55253 59.12524  1.000 39.35999 ? 225 SER B C   1 
ATOM   3295 O O   . SER B 1 226 ? 57.13585 58.14044 57.99640  1.000 44.55692 ? 225 SER B O   1 
ATOM   3296 C CB  . SER B 1 226 ? 58.18030 56.85669 60.77339  1.000 35.52261 ? 225 SER B CB  1 
ATOM   3297 O OG  . SER B 1 226 ? 58.68914 56.13680 59.66783  1.000 46.33667 ? 225 SER B OG  1 
ATOM   3298 N N   . GLY B 1 227 ? 57.96809 59.72852 59.35553  1.000 42.51026 ? 226 GLY B N   1 
ATOM   3299 C CA  . GLY B 1 227 ? 58.39857 60.58785 58.26733  1.000 37.66826 ? 226 GLY B CA  1 
ATOM   3300 C C   . GLY B 1 227 ? 57.35039 60.81920 57.19856  1.000 38.87029 ? 226 GLY B C   1 
ATOM   3301 O O   . GLY B 1 227 ? 57.52513 60.40554 56.04697  1.000 43.17231 ? 226 GLY B O   1 
ATOM   3302 N N   . LEU B 1 228 ? 56.25355 61.47512 57.58292  1.000 36.45904 ? 227 LEU B N   1 
ATOM   3303 C CA  . LEU B 1 228 ? 55.13837 61.79790 56.69962  1.000 35.74456 ? 227 LEU B CA  1 
ATOM   3304 C C   . LEU B 1 228 ? 55.58059 62.45333 55.40012  1.000 35.54886 ? 227 LEU B C   1 
ATOM   3305 O O   . LEU B 1 228 ? 56.72858 62.89403 55.27774  1.000 35.25873 ? 227 LEU B O   1 
ATOM   3306 C CB  . LEU B 1 228 ? 54.17139 62.74455 57.40909  1.000 35.33702 ? 227 LEU B CB  1 
ATOM   3307 C CG  . LEU B 1 228 ? 53.08314 62.21635 58.32992  1.000 30.13188 ? 227 LEU B CG  1 
ATOM   3308 C CD1 . LEU B 1 228 ? 52.78791 63.28395 59.34768  1.000 31.59745 ? 227 LEU B CD1 1 
ATOM   3309 C CD2 . LEU B 1 228 ? 51.84121 61.89316 57.53841  1.000 23.72032 ? 227 LEU B CD2 1 
ATOM   3310 N N   . GLN B 1 229 ? 54.67363 62.50690 54.42292  1.000 34.83090 ? 228 GLN B N   1 
ATOM   3311 C CA  . GLN B 1 229 ? 54.90501 63.17223 53.14216  1.000 33.00131 ? 228 GLN B CA  1 
ATOM   3312 C C   . GLN B 1 229 ? 53.56360 63.72886 52.67610  1.000 31.31128 ? 228 GLN B C   1 
ATOM   3313 O O   . GLN B 1 229 ? 52.50203 63.30002 53.13846  1.000 36.31157 ? 228 GLN B O   1 
ATOM   3314 C CB  . GLN B 1 229 ? 55.54595 62.23603 52.10559  1.000 35.40507 ? 228 GLN B CB  1 
ATOM   3315 C CG  . GLN B 1 229 ? 56.88394 61.65341 52.57595  1.000 40.03565 ? 228 GLN B CG  1 
ATOM   3316 C CD  . GLN B 1 229 ? 57.60333 60.80042 51.54712  1.000 45.94645 ? 228 GLN B CD  1 
ATOM   3317 O OE1 . GLN B 1 229 ? 57.09373 60.56215 50.44725  1.000 42.66902 ? 228 GLN B OE1 1 
ATOM   3318 N NE2 . GLN B 1 229 ? 58.78534 60.29437 51.92176  1.000 47.91880 ? 228 GLN B NE2 1 
ATOM   3319 N N   . ALA B 1 230 ? 53.61679 64.70226 51.76530  1.000 32.43738 ? 229 ALA B N   1 
ATOM   3320 C CA  . ALA B 1 230 ? 52.40205 65.40391 51.34445  1.000 32.10340 ? 229 ALA B CA  1 
ATOM   3321 C C   . ALA B 1 230 ? 51.34903 64.45324 50.78564  1.000 31.72194 ? 229 ALA B C   1 
ATOM   3322 O O   . ALA B 1 230 ? 50.14495 64.65856 50.99396  1.000 26.77098 ? 229 ALA B O   1 
ATOM   3323 C CB  . ALA B 1 230 ? 52.74774 66.47372 50.31432  1.000 29.02887 ? 229 ALA B CB  1 
ATOM   3324 N N   . GLU B 1 231 ? 51.77714 63.43898 50.02870  1.000 30.65206 ? 230 GLU B N   1 
ATOM   3325 C CA  . GLU B 1 231 ? 50.84790 62.45966 49.46421  1.000 31.29851 ? 230 GLU B CA  1 
ATOM   3326 C C   . GLU B 1 231 ? 50.11460 61.63203 50.51538  1.000 34.30918 ? 230 GLU B C   1 
ATOM   3327 O O   . GLU B 1 231 ? 49.23066 60.85214 50.14224  1.000 31.53032 ? 230 GLU B O   1 
ATOM   3328 C CB  . GLU B 1 231 ? 51.56064 61.50917 48.50589  1.000 27.50823 ? 230 GLU B CB  1 
ATOM   3329 C CG  . GLU B 1 231 ? 52.51472 60.53486 49.15164  1.000 28.95469 ? 230 GLU B CG  1 
ATOM   3330 C CD  . GLU B 1 231 ? 53.95685 61.02063 49.10930  1.000 45.97844 ? 230 GLU B CD  1 
ATOM   3331 O OE1 . GLU B 1 231 ? 54.16268 62.26033 49.04945  1.000 44.22665 ? 230 GLU B OE1 1 
ATOM   3332 O OE2 . GLU B 1 231 ? 54.87959 60.16324 49.11152  1.000 44.46939 ? 230 GLU B OE2 1 
ATOM   3333 N N   . ASP B 1 232 ? 50.51831 61.69749 51.78803  1.000 37.65159 ? 231 ASP B N   1 
ATOM   3334 C CA  . ASP B 1 232 ? 49.92987 60.89112 52.85078  1.000 30.89742 ? 231 ASP B CA  1 
ATOM   3335 C C   . ASP B 1 232 ? 48.66714 61.51889 53.43556  1.000 27.75242 ? 231 ASP B C   1 
ATOM   3336 O O   . ASP B 1 232 ? 48.13687 61.02475 54.42897  1.000 26.14692 ? 231 ASP B O   1 
ATOM   3337 C CB  . ASP B 1 232 ? 50.96406 60.61748 53.93583  1.000 27.58719 ? 231 ASP B CB  1 
ATOM   3338 C CG  . ASP B 1 232 ? 52.11674 59.76521 53.43029  1.000 33.42637 ? 231 ASP B CG  1 
ATOM   3339 O OD1 . ASP B 1 232 ? 51.87055 58.89021 52.57097  1.000 35.40393 ? 231 ASP B OD1 1 
ATOM   3340 O OD2 . ASP B 1 232 ? 53.26768 59.96273 53.88839  1.000 36.12622 ? 231 ASP B OD2 1 
ATOM   3341 N N   . GLU B 1 233 ? 48.17584 62.59422 52.85030  1.000 28.61144 ? 232 GLU B N   1 
ATOM   3342 C CA  . GLU B 1 233 ? 47.00443 63.26549 53.39107  1.000 31.18484 ? 232 GLU B CA  1 
ATOM   3343 C C   . GLU B 1 233 ? 45.79276 62.46752 52.92227  1.000 27.70016 ? 232 GLU B C   1 
ATOM   3344 O O   . GLU B 1 233 ? 45.37730 62.56357 51.76881  1.000 32.53614 ? 232 GLU B O   1 
ATOM   3345 C CB  . GLU B 1 233 ? 46.97290 64.71869 52.91335  1.000 21.88450 ? 232 GLU B CB  1 
ATOM   3346 C CG  . GLU B 1 233 ? 45.94052 65.60793 53.58364  1.000 33.28965 ? 232 GLU B CG  1 
ATOM   3347 C CD  . GLU B 1 233 ? 46.33470 67.10575 53.61187  1.000 45.00593 ? 232 GLU B CD  1 
ATOM   3348 O OE1 . GLU B 1 233 ? 45.62172 67.89672 54.26879  1.000 38.81725 ? 232 GLU B OE1 1 
ATOM   3349 O OE2 . GLU B 1 233 ? 47.35681 67.49654 52.99983  1.000 48.64928 ? 232 GLU B OE2 1 
ATOM   3350 N N   . ALA B 1 234 ? 45.19856 61.68914 53.81344  1.000 21.06640 ? 233 ALA B N   1 
ATOM   3351 C CA  . ALA B 1 234 ? 44.07922 60.85258 53.40877  1.000 24.69078 ? 233 ALA B CA  1 
ATOM   3352 C C   . ALA B 1 234 ? 43.25164 60.51016 54.63435  1.000 25.41076 ? 233 ALA B C   1 
ATOM   3353 O O   . ALA B 1 234 ? 43.58400 60.89351 55.75537  1.000 31.73681 ? 233 ALA B O   1 
ATOM   3354 C CB  . ALA B 1 234 ? 44.55678 59.58505 52.70609  1.000 23.16782 ? 233 ALA B CB  1 
ATOM   3355 N N   . ASP B 1 235 ? 42.15166 59.80360 54.40902  1.000 22.82088 ? 234 ASP B N   1 
ATOM   3356 C CA  . ASP B 1 235 ? 41.43307 59.15657 55.48716  1.000 22.18874 ? 234 ASP B CA  1 
ATOM   3357 C C   . ASP B 1 235 ? 42.00503 57.76290 55.60865  1.000 23.56908 ? 234 ASP B C   1 
ATOM   3358 O O   . ASP B 1 235 ? 42.30599 57.13531 54.59348  1.000 25.84249 ? 234 ASP B O   1 
ATOM   3359 C CB  . ASP B 1 235 ? 39.93097 59.07894 55.21784  1.000 26.63999 ? 234 ASP B CB  1 
ATOM   3360 C CG  . ASP B 1 235 ? 39.27207 60.45481 55.02982  1.000 27.61794 ? 234 ASP B CG  1 
ATOM   3361 O OD1 . ASP B 1 235 ? 39.48551 61.39104 55.83649  1.000 23.01066 ? 234 ASP B OD1 1 
ATOM   3362 O OD2 . ASP B 1 235 ? 38.49543 60.58463 54.06435  1.000 38.40009 ? 234 ASP B OD2 1 
ATOM   3363 N N   . TYR B 1 236 ? 42.23714 57.31581 56.84126  1.000 23.27952 ? 235 TYR B N   1 
ATOM   3364 C CA  . TYR B 1 236 ? 42.77956 55.98468 57.10223  1.000 23.71531 ? 235 TYR B CA  1 
ATOM   3365 C C   . TYR B 1 236 ? 41.77479 55.21471 57.94312  1.000 23.70048 ? 235 TYR B C   1 
ATOM   3366 O O   . TYR B 1 236 ? 41.43057 55.64478 59.04462  1.000 29.50994 ? 235 TYR B O   1 
ATOM   3367 C CB  . TYR B 1 236 ? 44.13219 56.03733 57.81248  1.000 21.52017 ? 235 TYR B CB  1 
ATOM   3368 C CG  . TYR B 1 236 ? 45.23231 56.63739 56.97642  1.000 24.57472 ? 235 TYR B CG  1 
ATOM   3369 C CD1 . TYR B 1 236 ? 45.38915 58.01393 56.88738  1.000 23.28562 ? 235 TYR B CD1 1 
ATOM   3370 C CD2 . TYR B 1 236 ? 46.12085 55.83014 56.27354  1.000 27.75126 ? 235 TYR B CD2 1 
ATOM   3371 C CE1 . TYR B 1 236 ? 46.40130 58.57917 56.12435  1.000 20.85429 ? 235 TYR B CE1 1 
ATOM   3372 C CE2 . TYR B 1 236 ? 47.13737 56.38416 55.50335  1.000 29.34501 ? 235 TYR B CE2 1 
ATOM   3373 C CZ  . TYR B 1 236 ? 47.26669 57.76556 55.43227  1.000 24.05551 ? 235 TYR B CZ  1 
ATOM   3374 O OH  . TYR B 1 236 ? 48.26542 58.32749 54.67284  1.000 22.06031 ? 235 TYR B OH  1 
ATOM   3375 N N   . TYR B 1 237 ? 41.28827 54.09848 57.42244  1.000 23.55402 ? 236 TYR B N   1 
ATOM   3376 C CA  . TYR B 1 237 ? 40.33393 53.25770 58.13424  1.000 25.90519 ? 236 TYR B CA  1 
ATOM   3377 C C   . TYR B 1 237 ? 41.03481 51.99472 58.64206  1.000 24.05793 ? 236 TYR B C   1 
ATOM   3378 O O   . TYR B 1 237 ? 41.99208 51.51046 58.04027  1.000 24.45094 ? 236 TYR B O   1 
ATOM   3379 C CB  . TYR B 1 237 ? 39.14632 52.87992 57.24641  1.000 23.94996 ? 236 TYR B CB  1 
ATOM   3380 C CG  . TYR B 1 237 ? 38.38411 54.06362 56.71300  1.000 26.81811 ? 236 TYR B CG  1 
ATOM   3381 C CD1 . TYR B 1 237 ? 38.92027 54.86603 55.71250  1.000 28.00463 ? 236 TYR B CD1 1 
ATOM   3382 C CD2 . TYR B 1 237 ? 37.12020 54.37730 57.19694  1.000 28.56184 ? 236 TYR B CD2 1 
ATOM   3383 C CE1 . TYR B 1 237 ? 38.23361 55.95835 55.23295  1.000 26.46572 ? 236 TYR B CE1 1 
ATOM   3384 C CE2 . TYR B 1 237 ? 36.42338 55.46278 56.71195  1.000 27.85395 ? 236 TYR B CE2 1 
ATOM   3385 C CZ  . TYR B 1 237 ? 36.98543 56.25078 55.73165  1.000 26.95860 ? 236 TYR B CZ  1 
ATOM   3386 O OH  . TYR B 1 237 ? 36.30109 57.34109 55.24086  1.000 29.72494 ? 236 TYR B OH  1 
ATOM   3387 N N   . CYS B 1 238 ? 40.62095 51.51915 59.80472  1.000 21.91772 ? 237 CYS B N   1 
ATOM   3388 C CA  . CYS B 1 238 ? 41.15297 50.28434 60.34600  1.000 27.96582 ? 237 CYS B CA  1 
ATOM   3389 C C   . CYS B 1 238 ? 40.08075 49.20815 60.28304  1.000 27.28776 ? 237 CYS B C   1 
ATOM   3390 O O   . CYS B 1 238 ? 38.88227 49.50323 60.31985  1.000 25.89106 ? 237 CYS B O   1 
ATOM   3391 C CB  . CYS B 1 238 ? 41.64647 50.47280 61.77925  1.000 28.60094 ? 237 CYS B CB  1 
ATOM   3392 S SG  . CYS B 1 238 ? 40.35740 50.87953 62.96756  1.000 54.21316 ? 237 CYS B SG  1 
ATOM   3393 N N   . SER B 1 239 ? 40.52498 47.95507 60.20079  1.000 25.96261 ? 238 SER B N   1 
ATOM   3394 C CA  . SER B 1 239 ? 39.62211 46.81963 60.06121  1.000 23.62470 ? 238 SER B CA  1 
ATOM   3395 C C   . SER B 1 239 ? 40.13249 45.62246 60.84489  1.000 26.54898 ? 238 SER B C   1 
ATOM   3396 O O   . SER B 1 239 ? 41.33741 45.45219 61.05246  1.000 20.74409 ? 238 SER B O   1 
ATOM   3397 C CB  . SER B 1 239 ? 39.45890 46.39809 58.60594  1.000 25.14967 ? 238 SER B CB  1 
ATOM   3398 O OG  . SER B 1 239 ? 40.70403 46.14770 57.98249  1.000 25.90027 ? 238 SER B OG  1 
ATOM   3399 N N   . SER B 1 240 ? 39.19215 44.78856 61.27512  1.000 31.89703 ? 239 SER B N   1 
ATOM   3400 C CA  . SER B 1 240 ? 39.52613 43.53120 61.91804  1.000 27.66336 ? 239 SER B CA  1 
ATOM   3401 C C   . SER B 1 240 ? 38.56633 42.44603 61.47444  1.000 31.24966 ? 239 SER B C   1 
ATOM   3402 O O   . SER B 1 240 ? 37.37958 42.70929 61.25831  1.000 31.91716 ? 239 SER B O   1 
ATOM   3403 C CB  . SER B 1 240 ? 39.47939 43.64380 63.44539  1.000 30.37435 ? 239 SER B CB  1 
ATOM   3404 O OG  . SER B 1 240 ? 40.16959 42.55470 64.04425  1.000 35.62851 ? 239 SER B OG  1 
ATOM   3405 N N   . TYR B 1 241 ? 39.09985 41.23306 61.32431  1.000 37.07490 ? 240 TYR B N   1 
ATOM   3406 C CA  . TYR B 1 241 ? 38.27729 40.02741 61.34853  1.000 35.40420 ? 240 TYR B CA  1 
ATOM   3407 C C   . TYR B 1 241 ? 37.49807 39.95473 62.66124  1.000 28.87145 ? 240 TYR B C   1 
ATOM   3408 O O   . TYR B 1 241 ? 38.02595 40.27369 63.72878  1.000 31.21907 ? 240 TYR B O   1 
ATOM   3409 C CB  . TYR B 1 241 ? 39.16999 38.79466 61.19908  1.000 32.23084 ? 240 TYR B CB  1 
ATOM   3410 C CG  . TYR B 1 241 ? 38.40877 37.49971 61.17609  1.000 36.04834 ? 240 TYR B CG  1 
ATOM   3411 C CD1 . TYR B 1 241 ? 38.74923 36.45523 62.02151  1.000 35.25994 ? 240 TYR B CD1 1 
ATOM   3412 C CD2 . TYR B 1 241 ? 37.33850 37.31970 60.30394  1.000 40.71532 ? 240 TYR B CD2 1 
ATOM   3413 C CE1 . TYR B 1 241 ? 38.05589 35.26850 61.99948  1.000 35.28286 ? 240 TYR B CE1 1 
ATOM   3414 C CE2 . TYR B 1 241 ? 36.63302 36.12356 60.27278  1.000 41.72527 ? 240 TYR B CE2 1 
ATOM   3415 C CZ  . TYR B 1 241 ? 37.00077 35.10345 61.12460  1.000 38.57922 ? 240 TYR B CZ  1 
ATOM   3416 O OH  . TYR B 1 241 ? 36.30349 33.91889 61.09755  1.000 45.81704 ? 240 TYR B OH  1 
ATOM   3417 N N   . ALA B 1 242 ? 36.24101 39.52894 62.59311  1.000 21.34793 ? 241 ALA B N   1 
ATOM   3418 C CA  . ALA B 1 242 ? 35.38583 39.60557 63.76975  1.000 25.97010 ? 241 ALA B CA  1 
ATOM   3419 C C   . ALA B 1 242 ? 34.64981 38.29857 64.04760  1.000 32.71742 ? 241 ALA B C   1 
ATOM   3420 O O   . ALA B 1 242 ? 33.54576 38.31057 64.60809  1.000 31.70740 ? 241 ALA B O   1 
ATOM   3421 C CB  . ALA B 1 242 ? 34.38861 40.75410 63.62721  1.000 34.61090 ? 241 ALA B CB  1 
ATOM   3422 N N   . GLY B 1 243 ? 35.26444 37.16080 63.72383  1.000 32.63759 ? 242 GLY B N   1 
ATOM   3423 C CA  . GLY B 1 243 ? 34.62979 35.88258 63.97434  1.000 37.62975 ? 242 GLY B CA  1 
ATOM   3424 C C   . GLY B 1 243 ? 33.63867 35.41534 62.91470  1.000 40.65219 ? 242 GLY B C   1 
ATOM   3425 O O   . GLY B 1 243 ? 33.47381 35.98864 61.83442  1.000 41.79088 ? 242 GLY B O   1 
ATOM   3426 N N   . SER B 1 244 ? 33.00439 34.29017 63.24157  1.000 44.30256 ? 243 SER B N   1 
ATOM   3427 C CA  . SER B 1 244 ? 32.11570 33.61118 62.30522  1.000 43.24355 ? 243 SER B CA  1 
ATOM   3428 C C   . SER B 1 244 ? 30.94083 34.49960 61.89719  1.000 42.51402 ? 243 SER B C   1 
ATOM   3429 O O   . SER B 1 244 ? 30.58080 34.55908 60.71679  1.000 45.49395 ? 243 SER B O   1 
ATOM   3430 C CB  . SER B 1 244 ? 31.58184 32.32775 62.95543  1.000 49.09632 ? 243 SER B CB  1 
ATOM   3431 O OG  . SER B 1 244 ? 32.58703 31.64415 63.69167  1.000 60.31906 ? 243 SER B OG  1 
ATOM   3432 N N   . TYR B 1 245 ? 30.33939 35.20607 62.86479  1.000 44.77996 ? 244 TYR B N   1 
ATOM   3433 C CA  . TYR B 1 245 ? 29.06494 35.89231 62.66699  1.000 34.59665 ? 244 TYR B CA  1 
ATOM   3434 C C   . TYR B 1 245 ? 29.22028 37.24074 61.98461  1.000 38.99431 ? 244 TYR B C   1 
ATOM   3435 O O   . TYR B 1 245 ? 28.49323 37.54879 61.03374  1.000 39.84277 ? 244 TYR B O   1 
ATOM   3436 C CB  . TYR B 1 245 ? 28.37404 36.07398 64.01424  1.000 42.78138 ? 244 TYR B CB  1 
ATOM   3437 C CG  . TYR B 1 245 ? 26.93329 36.54289 63.93045  1.000 51.55156 ? 244 TYR B CG  1 
ATOM   3438 C CD1 . TYR B 1 245 ? 26.62168 37.89807 63.82701  1.000 48.70016 ? 244 TYR B CD1 1 
ATOM   3439 C CD2 . TYR B 1 245 ? 25.88240 35.63341 63.97779  1.000 51.08276 ? 244 TYR B CD2 1 
ATOM   3440 C CE1 . TYR B 1 245 ? 25.30907 38.33067 63.76101  1.000 47.95259 ? 244 TYR B CE1 1 
ATOM   3441 C CE2 . TYR B 1 245 ? 24.56575 36.05840 63.91098  1.000 54.09113 ? 244 TYR B CE2 1 
ATOM   3442 C CZ  . TYR B 1 245 ? 24.28521 37.40446 63.80609  1.000 52.91234 ? 244 TYR B CZ  1 
ATOM   3443 O OH  . TYR B 1 245 ? 22.97424 37.81345 63.73607  1.000 54.15004 ? 244 TYR B OH  1 
ATOM   3444 N N   . ASN B 1 246 ? 30.10558 38.08668 62.50402  1.000 38.97900 ? 245 ASN B N   1 
ATOM   3445 C CA  . ASN B 1 246 ? 30.28394 39.42589 61.95611  1.000 43.88713 ? 245 ASN B CA  1 
ATOM   3446 C C   . ASN B 1 246 ? 31.31468 39.50119 60.83018  1.000 38.79153 ? 245 ASN B C   1 
ATOM   3447 O O   . ASN B 1 246 ? 31.31172 40.47761 60.07307  1.000 34.12325 ? 245 ASN B O   1 
ATOM   3448 C CB  . ASN B 1 246 ? 30.63217 40.38865 63.09344  1.000 39.41135 ? 245 ASN B CB  1 
ATOM   3449 C CG  . ASN B 1 246 ? 29.53400 40.44480 64.14191  1.000 40.44178 ? 245 ASN B CG  1 
ATOM   3450 O OD1 . ASN B 1 246 ? 28.34835 40.52284 63.80345  1.000 40.37193 ? 245 ASN B OD1 1 
ATOM   3451 N ND2 . ASN B 1 246 ? 29.91396 40.37677 65.41496  1.000 33.82598 ? 245 ASN B ND2 1 
ATOM   3452 N N   . PHE B 1 247 ? 32.18719 38.50233 60.70880  1.000 35.60051 ? 246 PHE B N   1 
ATOM   3453 C CA  . PHE B 1 247 ? 33.28399 38.48400 59.74413  1.000 36.43738 ? 246 PHE B CA  1 
ATOM   3454 C C   . PHE B 1 247 ? 34.21233 39.67481 59.96641  1.000 30.47734 ? 246 PHE B C   1 
ATOM   3455 O O   . PHE B 1 247 ? 35.16688 39.54284 60.72958  1.000 37.98281 ? 246 PHE B O   1 
ATOM   3456 C CB  . PHE B 1 247 ? 32.78581 38.42332 58.28484  1.000 36.11690 ? 246 PHE B CB  1 
ATOM   3457 C CG  . PHE B 1 247 ? 33.88945 38.09691 57.30370  1.000 37.34668 ? 246 PHE B CG  1 
ATOM   3458 C CD1 . PHE B 1 247 ? 34.61168 39.11429 56.67791  1.000 34.34492 ? 246 PHE B CD1 1 
ATOM   3459 C CD2 . PHE B 1 247 ? 34.26042 36.77428 57.06857  1.000 34.52510 ? 246 PHE B CD2 1 
ATOM   3460 C CE1 . PHE B 1 247 ? 35.65869 38.81936 55.82006  1.000 33.91135 ? 246 PHE B CE1 1 
ATOM   3461 C CE2 . PHE B 1 247 ? 35.30516 36.47183 56.20200  1.000 28.48251 ? 246 PHE B CE2 1 
ATOM   3462 C CZ  . PHE B 1 247 ? 36.01144 37.49746 55.58612  1.000 26.61298 ? 246 PHE B CZ  1 
ATOM   3463 N N   . TYR B 1 248 ? 33.98279 40.81139 59.29967  1.000 29.22861 ? 247 TYR B N   1 
ATOM   3464 C CA  . TYR B 1 248 ? 34.71870 42.05916 59.52066  1.000 31.82851 ? 247 TYR B CA  1 
ATOM   3465 C C   . TYR B 1 248 ? 33.99132 43.09210 60.37225  1.000 34.48744 ? 247 TYR B C   1 
ATOM   3466 O O   . TYR B 1 248 ? 32.77765 43.04190 60.57499  1.000 43.15879 ? 247 TYR B O   1 
ATOM   3467 C CB  . TYR B 1 248 ? 35.10152 42.81937 58.23935  1.000 36.03244 ? 247 TYR B CB  1 
ATOM   3468 C CG  . TYR B 1 248 ? 36.42415 42.58216 57.53529  1.000 39.60694 ? 247 TYR B CG  1 
ATOM   3469 C CD1 . TYR B 1 248 ? 37.39070 41.70933 58.01711  1.000 42.35667 ? 247 TYR B CD1 1 
ATOM   3470 C CD2 . TYR B 1 248 ? 36.83906 43.52682 56.58535  1.000 39.53456 ? 247 TYR B CD2 1 
ATOM   3471 C CE1 . TYR B 1 248 ? 38.66341 41.63582 57.39535  1.000 44.18329 ? 247 TYR B CE1 1 
ATOM   3472 C CE2 . TYR B 1 248 ? 38.08956 43.48440 55.99194  1.000 38.91433 ? 247 TYR B CE2 1 
ATOM   3473 C CZ  . TYR B 1 248 ? 38.99851 42.54618 56.39368  1.000 40.40622 ? 247 TYR B CZ  1 
ATOM   3474 O OH  . TYR B 1 248 ? 40.22558 42.53832 55.76760  1.000 40.64911 ? 247 TYR B OH  1 
ATOM   3475 N N   . VAL B 1 249 ? 34.79244 44.05115 60.85983  1.000 35.38520 ? 248 VAL B N   1 
ATOM   3476 C CA  . VAL B 1 249 ? 34.35739 45.34909 61.37806  1.000 32.31076 ? 248 VAL B CA  1 
ATOM   3477 C C   . VAL B 1 249 ? 35.39815 46.38008 60.96235  1.000 32.57254 ? 248 VAL B C   1 
ATOM   3478 O O   . VAL B 1 249 ? 36.55208 46.05333 60.66273  1.000 31.00993 ? 248 VAL B O   1 
ATOM   3479 C CB  . VAL B 1 249 ? 34.17228 45.41509 62.91248  1.000 26.36655 ? 248 VAL B CB  1 
ATOM   3480 C CG1 . VAL B 1 249 ? 32.95913 44.61285 63.34127  1.000 29.28802 ? 248 VAL B CG1 1 
ATOM   3481 C CG2 . VAL B 1 249 ? 35.43047 44.96131 63.62537  1.000 23.96215 ? 248 VAL B CG2 1 
ATOM   3482 N N   . PHE B 1 250 ? 34.97188 47.64118 60.93516  1.000 37.94049 ? 249 PHE B N   1 
ATOM   3483 C CA  . PHE B 1 250 ? 35.82432 48.74597 60.52404  1.000 29.06851 ? 249 PHE B CA  1 
ATOM   3484 C C   . PHE B 1 250 ? 35.88848 49.81167 61.61204  1.000 28.49810 ? 249 PHE B C   1 
ATOM   3485 O O   . PHE B 1 250 ? 35.07935 49.83051 62.53980  1.000 32.30736 ? 249 PHE B O   1 
ATOM   3486 C CB  . PHE B 1 250 ? 35.30530 49.35754 59.21945  1.000 29.69845 ? 249 PHE B CB  1 
ATOM   3487 C CG  . PHE B 1 250 ? 35.68353 48.57450 57.99069  1.000 30.63757 ? 249 PHE B CG  1 
ATOM   3488 C CD1 . PHE B 1 250 ? 37.00649 48.44743 57.61678  1.000 26.61484 ? 249 PHE B CD1 1 
ATOM   3489 C CD2 . PHE B 1 250 ? 34.71587 47.97947 57.19809  1.000 34.06547 ? 249 PHE B CD2 1 
ATOM   3490 C CE1 . PHE B 1 250 ? 37.36191 47.73623 56.48558  1.000 24.56780 ? 249 PHE B CE1 1 
ATOM   3491 C CE2 . PHE B 1 250 ? 35.06775 47.26737 56.05646  1.000 33.65083 ? 249 PHE B CE2 1 
ATOM   3492 C CZ  . PHE B 1 250 ? 36.39472 47.14801 55.70425  1.000 26.39576 ? 249 PHE B CZ  1 
ATOM   3493 N N   . GLY B 1 251 ? 36.88835 50.69496 61.50908  1.000 31.13795 ? 250 GLY B N   1 
ATOM   3494 C CA  . GLY B 1 251 ? 36.86141 51.93170 62.26296  1.000 30.17364 ? 250 GLY B CA  1 
ATOM   3495 C C   . GLY B 1 251 ? 36.18316 53.07628 61.47930  1.000 34.44150 ? 250 GLY B C   1 
ATOM   3496 O O   . GLY B 1 251 ? 35.92062 52.99931 60.27179  1.000 25.17453 ? 250 GLY B O   1 
ATOM   3497 N N   . ASN B 1 252 ? 35.93098 54.17742 62.18979  1.000 37.64964 ? 251 ASN B N   1 
ATOM   3498 C CA  . ASN B 1 252 ? 35.30185 55.33072 61.55526  1.000 41.17793 ? 251 ASN B CA  1 
ATOM   3499 C C   . ASN B 1 252 ? 36.31061 56.16972 60.79459  1.000 36.88118 ? 251 ASN B C   1 
ATOM   3500 O O   . ASN B 1 252 ? 35.94061 57.18097 60.19881  1.000 36.17668 ? 251 ASN B O   1 
ATOM   3501 C CB  . ASN B 1 252 ? 34.59086 56.21850 62.58809  1.000 40.38390 ? 251 ASN B CB  1 
ATOM   3502 C CG  . ASN B 1 252 ? 33.40425 56.99360 61.99114  1.000 49.11006 ? 251 ASN B CG  1 
ATOM   3503 O OD1 . ASN B 1 252 ? 33.55833 57.83387 61.09814  1.000 49.24180 ? 251 ASN B OD1 1 
ATOM   3504 N ND2 . ASN B 1 252 ? 32.21148 56.71628 62.50716  1.000 52.03839 ? 251 ASN B ND2 1 
ATOM   3505 N N   . GLY B 1 253 ? 37.56904 55.79967 60.82558  1.000 33.00511 ? 252 GLY B N   1 
ATOM   3506 C CA  . GLY B 1 253 ? 38.44067 56.52271 59.93769  1.000 23.03449 ? 252 GLY B CA  1 
ATOM   3507 C C   . GLY B 1 253 ? 38.96276 57.77150 60.58779  1.000 28.98024 ? 252 GLY B C   1 
ATOM   3508 O O   . GLY B 1 253 ? 38.28500 58.43682 61.37808  1.000 30.61205 ? 252 GLY B O   1 
ATOM   3509 N N   . THR B 1 254 ? 40.17513 58.11978 60.19911  1.000 28.40461 ? 253 THR B N   1 
ATOM   3510 C CA  . THR B 1 254 ? 40.89446 59.25256 60.75232  1.000 24.69299 ? 253 THR B CA  1 
ATOM   3511 C C   . THR B 1 254 ? 41.52053 60.03648 59.62420  1.000 28.44414 ? 253 THR B C   1 
ATOM   3512 O O   . THR B 1 254 ? 42.33729 59.49716 58.86769  1.000 33.98544 ? 253 THR B O   1 
ATOM   3513 C CB  . THR B 1 254 ? 41.96054 58.75677 61.72116  1.000 28.69746 ? 253 THR B CB  1 
ATOM   3514 O OG1 . THR B 1 254 ? 42.74055 59.86197 62.18246  1.000 34.68020 ? 253 THR B OG1 1 
ATOM   3515 C CG2 . THR B 1 254 ? 42.80159 57.69940 61.08404  1.000 34.97796 ? 253 THR B CG2 1 
ATOM   3516 N N   . LYS B 1 255 ? 41.16428 61.30561 59.51409  1.000 33.24312 ? 254 LYS B N   1 
ATOM   3517 C CA  . LYS B 1 255 ? 41.79952 62.12717 58.49716  1.000 28.28729 ? 254 LYS B CA  1 
ATOM   3518 C C   . LYS B 1 255 ? 43.14314 62.55665 58.99828  1.000 27.34856 ? 254 LYS B C   1 
ATOM   3519 O O   . LYS B 1 255 ? 43.21423 63.33169 59.95306  1.000 33.24649 ? 254 LYS B O   1 
ATOM   3520 C CB  . LYS B 1 255 ? 41.02316 63.37837 58.14293  1.000 28.95538 ? 254 LYS B CB  1 
ATOM   3521 C CG  . LYS B 1 255 ? 41.78482 64.09959 57.06639  1.000 34.89095 ? 254 LYS B CG  1 
ATOM   3522 C CD  . LYS B 1 255 ? 41.08789 65.30737 56.41477  1.000 31.05832 ? 254 LYS B CD  1 
ATOM   3523 C CE  . LYS B 1 255 ? 42.17025 66.13527 55.60363  1.000 35.55797 ? 254 LYS B CE  1 
ATOM   3524 N NZ  . LYS B 1 255 ? 42.84115 65.26422 54.46437  1.000 28.20268 ? 254 LYS B NZ  1 
ATOM   3525 N N   . VAL B 1 256 ? 44.18438 62.09982 58.33196  1.000 26.40850 ? 255 VAL B N   1 
ATOM   3526 C CA  . VAL B 1 256 ? 45.53637 62.54608 58.61069  1.000 28.19441 ? 255 VAL B CA  1 
ATOM   3527 C C   . VAL B 1 256 ? 45.80196 63.75933 57.74108  1.000 27.56225 ? 255 VAL B C   1 
ATOM   3528 O O   . VAL B 1 256 ? 45.54372 63.74781 56.53145  1.000 28.04600 ? 255 VAL B O   1 
ATOM   3529 C CB  . VAL B 1 256 ? 46.55724 61.42755 58.35075  1.000 22.25576 ? 255 VAL B CB  1 
ATOM   3530 C CG1 . VAL B 1 256 ? 47.98729 61.97108 58.41724  1.000 19.79001 ? 255 VAL B CG1 1 
ATOM   3531 C CG2 . VAL B 1 256 ? 46.39440 60.33904 59.35473  1.000 26.34551 ? 255 VAL B CG2 1 
ATOM   3532 N N   . THR B 1 257 ? 46.30634 64.81164 58.35802  1.000 30.29886 ? 256 THR B N   1 
ATOM   3533 C CA  . THR B 1 257 ? 46.42872 66.08866 57.68967  1.000 29.78767 ? 256 THR B CA  1 
ATOM   3534 C C   . THR B 1 257 ? 47.88738 66.48162 57.73465  1.000 31.16142 ? 256 THR B C   1 
ATOM   3535 O O   . THR B 1 257 ? 48.54571 66.29621 58.76097  1.000 28.60728 ? 256 THR B O   1 
ATOM   3536 C CB  . THR B 1 257 ? 45.58765 67.13180 58.39894  1.000 30.57185 ? 256 THR B CB  1 
ATOM   3537 O OG1 . THR B 1 257 ? 44.26787 66.61052 58.61163  1.000 29.39827 ? 256 THR B OG1 1 
ATOM   3538 C CG2 . THR B 1 257 ? 45.45263 68.33713 57.50239  1.000 39.55510 ? 256 THR B CG2 1 
ATOM   3539 N N   . VAL B 1 258 ? 48.40665 66.97618 56.61723  1.000 38.83175 ? 257 VAL B N   1 
ATOM   3540 C CA  . VAL B 1 258 ? 49.80704 67.37033 56.51530  1.000 40.07271 ? 257 VAL B CA  1 
ATOM   3541 C C   . VAL B 1 258 ? 49.81920 68.89694 56.46030  1.000 44.70546 ? 257 VAL B C   1 
ATOM   3542 O O   . VAL B 1 258 ? 49.16518 69.49037 55.59130  1.000 46.36064 ? 257 VAL B O   1 
ATOM   3543 C CB  . VAL B 1 258 ? 50.46847 66.74913 55.27358  1.000 33.85989 ? 257 VAL B CB  1 
ATOM   3544 C CG1 . VAL B 1 258 ? 51.96892 66.92668 55.30209  1.000 33.85713 ? 257 VAL B CG1 1 
ATOM   3545 C CG2 . VAL B 1 258 ? 50.04803 65.32096 55.10468  1.000 40.36089 ? 257 VAL B CG2 1 
ATOM   3546 N N   . LEU B 1 259 ? 50.55091 69.52980 57.38712  1.000 45.39082 ? 258 LEU B N   1 
ATOM   3547 C CA  . LEU B 1 259 ? 50.31752 70.92597 57.78687  1.000 50.13149 ? 258 LEU B CA  1 
ATOM   3548 C C   . LEU B 1 259 ? 50.65357 71.91176 56.66496  1.000 56.87815 ? 258 LEU B C   1 
ATOM   3549 O O   . LEU B 1 259 ? 51.81647 72.26373 56.44744  1.000 55.06265 ? 258 LEU B O   1 
ATOM   3550 C CB  . LEU B 1 259 ? 51.11481 71.24453 59.04832  1.000 43.83873 ? 258 LEU B CB  1 
ATOM   3551 N N   . GLY B 1 260 ? 49.61768 72.38184 55.96593  1.000 64.30227 ? 259 GLY B N   1 
ATOM   3552 C CA  . GLY B 1 260 ? 49.72455 73.48339 55.02379  1.000 54.53567 ? 259 GLY B CA  1 
ATOM   3553 C C   . GLY B 1 260 ? 49.30399 74.77295 55.70985  1.000 51.77473 ? 259 GLY B C   1 
ATOM   3554 O O   . GLY B 1 260 ? 49.44294 74.90103 56.93244  1.000 32.52277 ? 259 GLY B O   1 
ATOM   3555 N N   . GLU C 1 2   ? 73.29972 62.45271 92.54144  1.000 32.41383 ? 1   GLU C N   1 
ATOM   3556 C CA  . GLU C 1 2   ? 72.75420 61.10622 92.42618  1.000 42.46075 ? 1   GLU C CA  1 
ATOM   3557 C C   . GLU C 1 2   ? 71.21847 61.12090 92.49937  1.000 41.40544 ? 1   GLU C C   1 
ATOM   3558 O O   . GLU C 1 2   ? 70.65154 61.59805 93.48271  1.000 43.63532 ? 1   GLU C O   1 
ATOM   3559 C CB  . GLU C 1 2   ? 73.33175 60.20075 93.51995  1.000 45.61675 ? 1   GLU C CB  1 
ATOM   3560 C CG  . GLU C 1 2   ? 74.85922 60.20475 93.61267  1.000 63.83756 ? 1   GLU C CG  1 
ATOM   3561 C CD  . GLU C 1 2   ? 75.54599 59.26917 92.60706  1.000 67.98529 ? 1   GLU C CD  1 
ATOM   3562 O OE1 . GLU C 1 2   ? 76.54677 59.68896 91.98414  1.000 57.16103 ? 1   GLU C OE1 1 
ATOM   3563 O OE2 . GLU C 1 2   ? 75.08410 58.11773 92.43566  1.000 61.89733 ? 1   GLU C OE2 1 
ATOM   3564 N N   . VAL C 1 3   ? 70.58464 60.58598 91.44391  1.000 35.38592 ? 2   VAL C N   1 
ATOM   3565 C CA  . VAL C 1 3   ? 69.14057 60.41071 91.23021  1.000 29.35817 ? 2   VAL C CA  1 
ATOM   3566 C C   . VAL C 1 3   ? 68.59249 61.64363 90.53991  1.000 32.07563 ? 2   VAL C C   1 
ATOM   3567 O O   . VAL C 1 3   ? 68.06385 62.55624 91.18364  1.000 32.75299 ? 2   VAL C O   1 
ATOM   3568 C CB  . VAL C 1 3   ? 68.32038 60.09837 92.49630  1.000 25.16849 ? 2   VAL C CB  1 
ATOM   3569 C CG1 . VAL C 1 3   ? 66.89924 59.76969 92.08672  1.000 23.84935 ? 2   VAL C CG1 1 
ATOM   3570 C CG2 . VAL C 1 3   ? 68.87833 58.90573 93.20106  1.000 26.70237 ? 2   VAL C CG2 1 
ATOM   3571 N N   . GLN C 1 4   ? 68.69376 61.65703 89.21622  1.000 35.87318 ? 3   GLN C N   1 
ATOM   3572 C CA  . GLN C 1 4   ? 68.17998 62.73879 88.39673  1.000 30.98291 ? 3   GLN C CA  1 
ATOM   3573 C C   . GLN C 1 4   ? 67.32569 62.14586 87.28895  1.000 29.79360 ? 3   GLN C C   1 
ATOM   3574 O O   . GLN C 1 4   ? 67.64004 61.07702 86.75573  1.000 27.85909 ? 3   GLN C O   1 
ATOM   3575 C CB  . GLN C 1 4   ? 69.31350 63.59851 87.80454  1.000 31.83989 ? 3   GLN C CB  1 
ATOM   3576 N N   . LEU C 1 5   ? 66.20387 62.81209 87.02343  1.000 27.32710 ? 4   LEU C N   1 
ATOM   3577 C CA  . LEU C 1 5   ? 65.28129 62.51348 85.93327  1.000 29.35259 ? 4   LEU C CA  1 
ATOM   3578 C C   . LEU C 1 5   ? 65.24181 63.73642 85.03282  1.000 36.43460 ? 4   LEU C C   1 
ATOM   3579 O O   . LEU C 1 5   ? 64.95793 64.83666 85.52277  1.000 37.66818 ? 4   LEU C O   1 
ATOM   3580 C CB  . LEU C 1 5   ? 63.88039 62.23671 86.46851  1.000 25.54938 ? 4   LEU C CB  1 
ATOM   3581 C CG  . LEU C 1 5   ? 63.44407 60.85823 86.92793  1.000 27.84674 ? 4   LEU C CG  1 
ATOM   3582 C CD1 . LEU C 1 5   ? 64.45986 60.30594 87.85852  1.000 23.92011 ? 4   LEU C CD1 1 
ATOM   3583 C CD2 . LEU C 1 5   ? 62.13290 61.04099 87.65818  1.000 27.11699 ? 4   LEU C CD2 1 
ATOM   3584 N N   . VAL C 1 6   ? 65.45970 63.56695 83.72299  1.000 37.47493 ? 5   VAL C N   1 
ATOM   3585 C CA  . VAL C 1 6   ? 65.57528 64.74836 82.87441  1.000 39.34084 ? 5   VAL C CA  1 
ATOM   3586 C C   . VAL C 1 6   ? 64.55845 64.48579 81.73824  1.000 34.06139 ? 5   VAL C C   1 
ATOM   3587 O O   . VAL C 1 6   ? 64.61326 63.44998 81.05652  1.000 34.65555 ? 5   VAL C O   1 
ATOM   3588 C CB  . VAL C 1 6   ? 67.02528 64.96813 82.35916  1.000 37.38085 ? 5   VAL C CB  1 
ATOM   3589 C CG1 . VAL C 1 6   ? 67.41517 64.20189 81.05437  1.000 44.41429 ? 5   VAL C CG1 1 
ATOM   3590 C CG2 . VAL C 1 6   ? 67.51607 66.43562 82.55482  1.000 44.20197 ? 5   VAL C CG2 1 
ATOM   3591 N N   . GLU C 1 7   ? 63.53579 65.28828 81.67215  1.000 32.11282 ? 6   GLU C N   1 
ATOM   3592 C CA  . GLU C 1 7   ? 62.50783 65.18086 80.65224  1.000 35.02978 ? 6   GLU C CA  1 
ATOM   3593 C C   . GLU C 1 7   ? 62.71468 66.15693 79.52273  1.000 38.61796 ? 6   GLU C C   1 
ATOM   3594 O O   . GLU C 1 7   ? 63.01335 67.33015 79.75703  1.000 43.43751 ? 6   GLU C O   1 
ATOM   3595 C CB  . GLU C 1 7   ? 61.19446 65.28094 81.40204  1.000 36.62199 ? 6   GLU C CB  1 
ATOM   3596 C CG  . GLU C 1 7   ? 61.43773 66.16188 82.58146  1.000 40.80335 ? 6   GLU C CG  1 
ATOM   3597 C CD  . GLU C 1 7   ? 60.37761 66.01167 83.55813  1.000 47.97240 ? 6   GLU C CD  1 
ATOM   3598 O OE1 . GLU C 1 7   ? 59.24980 65.69399 83.21486  1.000 53.71616 ? 6   GLU C OE1 1 
ATOM   3599 O OE2 . GLU C 1 7   ? 60.70637 65.74063 84.70453  1.000 43.34373 ? 6   GLU C OE2 1 
ATOM   3600 N N   . SER C 1 8   ? 62.61691 65.64045 78.31028  1.000 28.68723 ? 7   SER C N   1 
ATOM   3601 C CA  . SER C 1 8   ? 62.95138 66.36932 77.11945  1.000 33.14374 ? 7   SER C CA  1 
ATOM   3602 C C   . SER C 1 8   ? 61.83362 66.13018 76.13460  1.000 31.88883 ? 7   SER C C   1 
ATOM   3603 O O   . SER C 1 8   ? 61.00739 65.23057 76.29925  1.000 28.43842 ? 7   SER C O   1 
ATOM   3604 C CB  . SER C 1 8   ? 64.30891 65.92867 76.55649  1.000 30.40152 ? 7   SER C CB  1 
ATOM   3605 O OG  . SER C 1 8   ? 64.16286 64.78280 75.72954  1.000 34.60001 ? 7   SER C OG  1 
ATOM   3606 N N   . GLY C 1 9   ? 61.81971 66.96145 75.11636  1.000 36.10063 ? 8   GLY C N   1 
ATOM   3607 C CA  . GLY C 1 9   ? 60.76571 66.93922 74.13631  1.000 33.03842 ? 8   GLY C CA  1 
ATOM   3608 C C   . GLY C 1 9   ? 59.81494 68.06088 74.47908  1.000 42.82495 ? 8   GLY C C   1 
ATOM   3609 O O   . GLY C 1 9   ? 60.08328 68.90840 75.34170  1.000 43.04741 ? 8   GLY C O   1 
ATOM   3610 N N   . GLY C 1 10  ? 58.66363 68.04373 73.83158  1.000 33.37265 ? 9   GLY C N   1 
ATOM   3611 C CA  . GLY C 1 10  ? 57.69200 69.08709 74.05161  1.000 29.50997 ? 9   GLY C CA  1 
ATOM   3612 C C   . GLY C 1 10  ? 58.07451 70.38870 73.36676  1.000 40.50066 ? 9   GLY C C   1 
ATOM   3613 O O   . GLY C 1 10  ? 59.19131 70.59373 72.87729  1.000 33.78446 ? 9   GLY C O   1 
ATOM   3614 N N   . GLY C 1 11  ? 57.11139 71.28489 73.34608  1.000 39.98911 ? 10  GLY C N   1 
ATOM   3615 C CA  . GLY C 1 11  ? 57.21587 72.50862 72.58190  1.000 30.91123 ? 10  GLY C CA  1 
ATOM   3616 C C   . GLY C 1 11  ? 55.81684 72.93306 72.20016  1.000 31.23505 ? 10  GLY C C   1 
ATOM   3617 O O   . GLY C 1 11  ? 54.82826 72.38104 72.67215  1.000 30.25141 ? 10  GLY C O   1 
ATOM   3618 N N   . LEU C 1 12  ? 55.74417 73.97561 71.39370  1.000 33.66042 ? 11  LEU C N   1 
ATOM   3619 C CA  . LEU C 1 12  ? 54.44815 74.36410 70.85831  1.000 34.79196 ? 11  LEU C CA  1 
ATOM   3620 C C   . LEU C 1 12  ? 54.16170 73.49259 69.63964  1.000 27.75627 ? 11  LEU C C   1 
ATOM   3621 O O   . LEU C 1 12  ? 54.98919 73.43375 68.72265  1.000 28.88143 ? 11  LEU C O   1 
ATOM   3622 C CB  . LEU C 1 12  ? 54.42771 75.84215 70.50251  1.000 27.57726 ? 11  LEU C CB  1 
ATOM   3623 C CG  . LEU C 1 12  ? 53.17953 76.21554 69.72808  1.000 29.64719 ? 11  LEU C CG  1 
ATOM   3624 C CD1 . LEU C 1 12  ? 52.02356 76.54166 70.66117  1.000 31.09487 ? 11  LEU C CD1 1 
ATOM   3625 C CD2 . LEU C 1 12  ? 53.50944 77.36076 68.79287  1.000 32.95178 ? 11  LEU C CD2 1 
ATOM   3626 N N   . VAL C 1 13  ? 53.01813 72.78720 69.64976  1.000 27.97297 ? 12  VAL C N   1 
ATOM   3627 C CA  . VAL C 1 13  ? 52.61622 71.86195 68.58604  1.000 33.71941 ? 12  VAL C CA  1 
ATOM   3628 C C   . VAL C 1 13  ? 51.17086 72.12492 68.17222  1.000 31.30233 ? 12  VAL C C   1 
ATOM   3629 O O   . VAL C 1 13  ? 50.34943 72.58785 68.97181  1.000 29.74469 ? 12  VAL C O   1 
ATOM   3630 C CB  . VAL C 1 13  ? 52.79250 70.36129 68.95911  1.000 33.89214 ? 12  VAL C CB  1 
ATOM   3631 C CG1 . VAL C 1 13  ? 54.26603 70.02953 69.21104  1.000 31.04051 ? 12  VAL C CG1 1 
ATOM   3632 C CG2 . VAL C 1 13  ? 51.89581 69.95858 70.12306  1.000 23.55718 ? 12  VAL C CG2 1 
ATOM   3633 N N   . GLN C 1 14  ? 50.87762 71.85513 66.89191  1.000 31.46485 ? 13  GLN C N   1 
ATOM   3634 C CA  . GLN C 1 14  ? 49.51596 71.97385 66.36719  1.000 31.53763 ? 13  GLN C CA  1 
ATOM   3635 C C   . GLN C 1 14  ? 48.63225 70.83601 66.88055  1.000 29.89311 ? 13  GLN C C   1 
ATOM   3636 O O   . GLN C 1 14  ? 49.12443 69.74744 67.17888  1.000 28.92486 ? 13  GLN C O   1 
ATOM   3637 C CB  . GLN C 1 14  ? 49.52362 71.94390 64.83740  1.000 31.29304 ? 13  GLN C CB  1 
ATOM   3638 C CG  . GLN C 1 14  ? 49.85561 73.27323 64.18181  1.000 34.68127 ? 13  GLN C CG  1 
ATOM   3639 C CD  . GLN C 1 14  ? 51.08008 73.89325 64.80602  1.000 40.02791 ? 13  GLN C CD  1 
ATOM   3640 O OE1 . GLN C 1 14  ? 52.19718 73.37313 64.66239  1.000 35.31140 ? 13  GLN C OE1 1 
ATOM   3641 N NE2 . GLN C 1 14  ? 50.87646 74.98345 65.55743  1.000 38.21481 ? 13  GLN C NE2 1 
ATOM   3642 N N   . PRO C 1 15  ? 47.31863 71.04995 66.96464  1.000 29.74304 ? 14  PRO C N   1 
ATOM   3643 C CA  . PRO C 1 15  ? 46.44432 70.02673 67.54319  1.000 28.31294 ? 14  PRO C CA  1 
ATOM   3644 C C   . PRO C 1 15  ? 46.37785 68.79245 66.64973  1.000 34.11330 ? 14  PRO C C   1 
ATOM   3645 O O   . PRO C 1 15  ? 46.80098 68.79557 65.49127  1.000 27.04799 ? 14  PRO C O   1 
ATOM   3646 C CB  . PRO C 1 15  ? 45.08688 70.72594 67.65206  1.000 23.64596 ? 14  PRO C CB  1 
ATOM   3647 C CG  . PRO C 1 15  ? 45.33137 72.15657 67.31296  1.000 25.32441 ? 14  PRO C CG  1 
ATOM   3648 C CD  . PRO C 1 15  ? 46.53650 72.18444 66.45485  1.000 24.77149 ? 14  PRO C CD  1 
ATOM   3649 N N   . GLY C 1 16  ? 45.85211 67.70669 67.22360  1.000 34.46896 ? 15  GLY C N   1 
ATOM   3650 C CA  . GLY C 1 16  ? 45.82716 66.43068 66.53925  1.000 24.07322 ? 15  GLY C CA  1 
ATOM   3651 C C   . GLY C 1 16  ? 47.21193 65.87498 66.28136  1.000 26.39126 ? 15  GLY C C   1 
ATOM   3652 O O   . GLY C 1 16  ? 47.36034 64.87717 65.57474  1.000 33.94884 ? 15  GLY C O   1 
ATOM   3653 N N   . ARG C 1 17  ? 48.23988 66.49566 66.84135  1.000 25.13694 ? 16  ARG C N   1 
ATOM   3654 C CA  . ARG C 1 17  ? 49.57950 66.01524 66.57825  1.000 24.87810 ? 16  ARG C CA  1 
ATOM   3655 C C   . ARG C 1 17  ? 49.94889 64.83833 67.49734  1.000 31.25675 ? 16  ARG C C   1 
ATOM   3656 O O   . ARG C 1 17  ? 49.28293 64.56201 68.50384  1.000 29.46597 ? 16  ARG C O   1 
ATOM   3657 C CB  . ARG C 1 17  ? 50.58627 67.14205 66.75487  1.000 23.41722 ? 16  ARG C CB  1 
ATOM   3658 C CG  . ARG C 1 17  ? 51.75427 66.84288 65.93482  1.000 29.82092 ? 16  ARG C CG  1 
ATOM   3659 C CD  . ARG C 1 17  ? 52.94164 67.64651 66.13969  1.000 30.11332 ? 16  ARG C CD  1 
ATOM   3660 N NE  . ARG C 1 17  ? 53.99281 66.75274 65.69983  1.000 33.93999 ? 16  ARG C NE  1 
ATOM   3661 C CZ  . ARG C 1 17  ? 55.28640 66.96032 65.85641  1.000 37.46480 ? 16  ARG C CZ  1 
ATOM   3662 N NH1 . ARG C 1 17  ? 55.72518 68.07716 66.42183  1.000 37.15437 ? 16  ARG C NH1 1 
ATOM   3663 N NH2 . ARG C 1 17  ? 56.13925 66.03988 65.42651  1.000 46.38079 ? 16  ARG C NH2 1 
ATOM   3664 N N   . SER C 1 18  ? 51.05785 64.16018 67.16274  1.000 31.73476 ? 17  SER C N   1 
ATOM   3665 C CA  . SER C 1 18  ? 51.62445 63.10759 67.99833  1.000 25.44307 ? 17  SER C CA  1 
ATOM   3666 C C   . SER C 1 18  ? 52.99305 63.55132 68.49482  1.000 22.92538 ? 17  SER C C   1 
ATOM   3667 O O   . SER C 1 18  ? 53.79587 64.07570 67.72370  1.000 27.15473 ? 17  SER C O   1 
ATOM   3668 C CB  . SER C 1 18  ? 51.74691 61.77179 67.23392  1.000 29.17368 ? 17  SER C CB  1 
ATOM   3669 O OG  . SER C 1 18  ? 50.50298 61.07421 67.17513  1.000 28.67739 ? 17  SER C OG  1 
ATOM   3670 N N   . LEU C 1 19  ? 53.28323 63.26899 69.76603  1.000 26.59330 ? 18  LEU C N   1 
ATOM   3671 C CA  . LEU C 1 19  ? 54.49272 63.73857 70.43969  1.000 27.13121 ? 18  LEU C CA  1 
ATOM   3672 C C   . LEU C 1 19  ? 55.00979 62.68511 71.41616  1.000 29.28896 ? 18  LEU C C   1 
ATOM   3673 O O   . LEU C 1 19  ? 54.23163 62.10196 72.18173  1.000 30.55501 ? 18  LEU C O   1 
ATOM   3674 C CB  . LEU C 1 19  ? 54.19087 65.04750 71.20275  1.000 29.01034 ? 18  LEU C CB  1 
ATOM   3675 C CG  . LEU C 1 19  ? 55.21298 66.17908 71.38317  1.000 30.85223 ? 18  LEU C CG  1 
ATOM   3676 C CD1 . LEU C 1 19  ? 55.72632 66.71501 70.04790  1.000 26.05409 ? 18  LEU C CD1 1 
ATOM   3677 C CD2 . LEU C 1 19  ? 54.59604 67.30028 72.20943  1.000 26.83297 ? 18  LEU C CD2 1 
ATOM   3678 N N   . ARG C 1 20  ? 56.32791 62.47532 71.43242  1.000 26.57210 ? 19  ARG C N   1 
ATOM   3679 C CA  . ARG C 1 20  ? 56.94406 61.53874 72.36834  1.000 26.32046 ? 19  ARG C CA  1 
ATOM   3680 C C   . ARG C 1 20  ? 57.86161 62.27484 73.32767  1.000 25.32536 ? 19  ARG C C   1 
ATOM   3681 O O   . ARG C 1 20  ? 58.85888 62.86653 72.90378  1.000 25.22564 ? 19  ARG C O   1 
ATOM   3682 C CB  . ARG C 1 20  ? 57.74832 60.45440 71.65283  1.000 28.21096 ? 19  ARG C CB  1 
ATOM   3683 C CG  . ARG C 1 20  ? 58.52874 59.58475 72.64195  1.000 27.53905 ? 19  ARG C CG  1 
ATOM   3684 C CD  . ARG C 1 20  ? 59.17196 58.38091 71.98831  1.000 32.87677 ? 19  ARG C CD  1 
ATOM   3685 N NE  . ARG C 1 20  ? 60.60612 58.58761 71.80451  1.000 36.51553 ? 19  ARG C NE  1 
ATOM   3686 C CZ  . ARG C 1 20  ? 61.40710 57.71916 71.19510  1.000 37.71871 ? 19  ARG C CZ  1 
ATOM   3687 N NH1 . ARG C 1 20  ? 60.89905 56.59166 70.69725  1.000 29.00608 ? 19  ARG C NH1 1 
ATOM   3688 N NH2 . ARG C 1 20  ? 62.70661 57.98674 71.06811  1.000 33.81266 ? 19  ARG C NH2 1 
ATOM   3689 N N   . LEU C 1 21  ? 57.56147 62.18532 74.61813  1.000 24.96505 ? 20  LEU C N   1 
ATOM   3690 C CA  . LEU C 1 21  ? 58.41691 62.76350 75.63320  1.000 20.14559 ? 20  LEU C CA  1 
ATOM   3691 C C   . LEU C 1 21  ? 59.39161 61.71476 76.12328  1.000 24.25906 ? 20  LEU C C   1 
ATOM   3692 O O   . LEU C 1 21  ? 59.02154 60.55347 76.30916  1.000 23.94932 ? 20  LEU C O   1 
ATOM   3693 C CB  . LEU C 1 21  ? 57.58651 63.28471 76.79270  1.000 19.29837 ? 20  LEU C CB  1 
ATOM   3694 C CG  . LEU C 1 21  ? 56.54180 64.25465 76.28572  1.000 24.02385 ? 20  LEU C CG  1 
ATOM   3695 C CD1 . LEU C 1 21  ? 55.79341 64.80807 77.45526  1.000 24.74257 ? 20  LEU C CD1 1 
ATOM   3696 C CD2 . LEU C 1 21  ? 57.24418 65.36585 75.50501  1.000 28.51579 ? 20  LEU C CD2 1 
ATOM   3697 N N   . SER C 1 22  ? 60.62320 62.14392 76.37696  1.000 24.86069 ? 21  SER C N   1 
ATOM   3698 C CA  . SER C 1 22  ? 61.65120 61.29514 76.95286  1.000 21.41252 ? 21  SER C CA  1 
ATOM   3699 C C   . SER C 1 22  ? 61.77850 61.59904 78.43297  1.000 26.19116 ? 21  SER C C   1 
ATOM   3700 O O   . SER C 1 22  ? 61.61460 62.73421 78.87763  1.000 29.00125 ? 21  SER C O   1 
ATOM   3701 C CB  . SER C 1 22  ? 63.01620 61.53787 76.31120  1.000 19.90687 ? 21  SER C CB  1 
ATOM   3702 O OG  . SER C 1 22  ? 63.10489 60.99025 75.01346  1.000 32.50194 ? 21  SER C OG  1 
ATOM   3703 N N   . CYS C 1 23  ? 62.09438 60.57801 79.20200  1.000 30.84247 ? 22  CYS C N   1 
ATOM   3704 C CA  . CYS C 1 23  ? 62.44502 60.79127 80.59407  1.000 29.66541 ? 22  CYS C CA  1 
ATOM   3705 C C   . CYS C 1 23  ? 63.71487 59.99765 80.83662  1.000 27.76233 ? 22  CYS C C   1 
ATOM   3706 O O   . CYS C 1 23  ? 63.67968 58.76887 80.85920  1.000 31.18578 ? 22  CYS C O   1 
ATOM   3707 C CB  . CYS C 1 23  ? 61.32083 60.34930 81.51137  1.000 23.76258 ? 22  CYS C CB  1 
ATOM   3708 S SG  . CYS C 1 23  ? 61.76846 60.37548 83.21880  1.000 37.12986 ? 22  CYS C SG  1 
ATOM   3709 N N   . SER C 1 24  ? 64.82177 60.68975 81.05871  1.000 29.68072 ? 23  SER C N   1 
ATOM   3710 C CA  . SER C 1 24  ? 66.11273 60.04114 81.22295  1.000 28.83169 ? 23  SER C CA  1 
ATOM   3711 C C   . SER C 1 24  ? 66.44678 60.02914 82.69502  1.000 27.06507 ? 23  SER C C   1 
ATOM   3712 O O   . SER C 1 24  ? 66.68825 61.07855 83.29708  1.000 28.16394 ? 23  SER C O   1 
ATOM   3713 C CB  . SER C 1 24  ? 67.20580 60.75799 80.44305  1.000 25.65888 ? 23  SER C CB  1 
ATOM   3714 O OG  . SER C 1 24  ? 66.99728 60.57215 79.06716  1.000 33.14934 ? 23  SER C OG  1 
ATOM   3715 N N   . ALA C 1 25  ? 66.47965 58.83929 83.26140  1.000 29.73509 ? 24  ALA C N   1 
ATOM   3716 C CA  . ALA C 1 25  ? 66.81004 58.67414 84.65812  1.000 21.61528 ? 24  ALA C CA  1 
ATOM   3717 C C   . ALA C 1 25  ? 68.27887 58.34308 84.75697  1.000 16.38560 ? 24  ALA C C   1 
ATOM   3718 O O   . ALA C 1 25  ? 68.89412 57.92476 83.78995  1.000 20.35986 ? 24  ALA C O   1 
ATOM   3719 C CB  . ALA C 1 25  ? 65.95530 57.58393 85.28218  1.000 19.11587 ? 24  ALA C CB  1 
ATOM   3720 N N   . SER C 1 26  ? 68.83072 58.52421 85.94261  1.000 19.63982 ? 25  SER C N   1 
ATOM   3721 C CA  . SER C 1 26  ? 70.21890 58.19465 86.21417  1.000 20.41394 ? 25  SER C CA  1 
ATOM   3722 C C   . SER C 1 26  ? 70.39074 58.22535 87.71626  1.000 24.53003 ? 25  SER C C   1 
ATOM   3723 O O   . SER C 1 26  ? 69.71398 58.99770 88.40146  1.000 32.07509 ? 25  SER C O   1 
ATOM   3724 C CB  . SER C 1 26  ? 71.16289 59.19681 85.57398  1.000 20.80667 ? 25  SER C CB  1 
ATOM   3725 O OG  . SER C 1 26  ? 70.75048 60.50034 85.97571  1.000 28.16508 ? 25  SER C OG  1 
ATOM   3726 N N   . GLY C 1 27  ? 71.24972 57.35217 88.22726  1.000 20.32749 ? 26  GLY C N   1 
ATOM   3727 C CA  . GLY C 1 27  ? 71.59739 57.37353 89.63439  1.000 28.35672 ? 26  GLY C CA  1 
ATOM   3728 C C   . GLY C 1 27  ? 71.00999 56.25292 90.46157  1.000 25.72785 ? 26  GLY C C   1 
ATOM   3729 O O   . GLY C 1 27  ? 71.27846 56.19222 91.66859  1.000 24.35378 ? 26  GLY C O   1 
ATOM   3730 N N   . PHE C 1 28  ? 70.19717 55.39149 89.85917  1.000 22.69885 ? 27  PHE C N   1 
ATOM   3731 C CA  . PHE C 1 28  ? 69.59480 54.24702 90.52111  1.000 21.91750 ? 27  PHE C CA  1 
ATOM   3732 C C   . PHE C 1 28  ? 69.43626 53.14622 89.48222  1.000 26.66462 ? 27  PHE C C   1 
ATOM   3733 O O   . PHE C 1 28  ? 69.65218 53.36636 88.28947  1.000 36.28644 ? 27  PHE C O   1 
ATOM   3734 C CB  . PHE C 1 28  ? 68.25831 54.61047 91.14905  1.000 20.78786 ? 27  PHE C CB  1 
ATOM   3735 C CG  . PHE C 1 28  ? 67.24829 55.11728 90.17007  1.000 25.90026 ? 27  PHE C CG  1 
ATOM   3736 C CD1 . PHE C 1 28  ? 67.13234 56.47891 89.92115  1.000 25.30312 ? 27  PHE C CD1 1 
ATOM   3737 C CD2 . PHE C 1 28  ? 66.39223 54.23256 89.50907  1.000 25.08220 ? 27  PHE C CD2 1 
ATOM   3738 C CE1 . PHE C 1 28  ? 66.18706 56.96145 89.02411  1.000 25.32904 ? 27  PHE C CE1 1 
ATOM   3739 C CE2 . PHE C 1 28  ? 65.45148 54.69470 88.61270  1.000 25.00102 ? 27  PHE C CE2 1 
ATOM   3740 C CZ  . PHE C 1 28  ? 65.34955 56.07169 88.35894  1.000 25.32931 ? 27  PHE C CZ  1 
ATOM   3741 N N   . THR C 1 29  ? 69.06990 51.94869 89.93208  1.000 23.05467 ? 28  THR C N   1 
ATOM   3742 C CA  . THR C 1 29  ? 68.96729 50.81119 89.01457  1.000 24.55695 ? 28  THR C CA  1 
ATOM   3743 C C   . THR C 1 29  ? 67.59856 50.83135 88.36050  1.000 28.77547 ? 28  THR C C   1 
ATOM   3744 O O   . THR C 1 29  ? 66.61246 50.33996 88.90795  1.000 32.50189 ? 28  THR C O   1 
ATOM   3745 C CB  . THR C 1 29  ? 69.22912 49.50369 89.72671  1.000 23.09175 ? 28  THR C CB  1 
ATOM   3746 O OG1 . THR C 1 29  ? 70.56457 49.53796 90.23736  1.000 30.25475 ? 28  THR C OG1 1 
ATOM   3747 C CG2 . THR C 1 29  ? 69.10299 48.36385 88.74235  1.000 28.58992 ? 28  THR C CG2 1 
ATOM   3748 N N   . PHE C 1 30  ? 67.55558 51.43050 87.17119  1.000 24.83684 ? 29  PHE C N   1 
ATOM   3749 C CA  . PHE C 1 30  ? 66.30050 51.83171 86.56732  1.000 20.79423 ? 29  PHE C CA  1 
ATOM   3750 C C   . PHE C 1 30  ? 65.27350 50.71192 86.63033  1.000 24.60033 ? 29  PHE C C   1 
ATOM   3751 O O   . PHE C 1 30  ? 64.12142 50.93598 87.01023  1.000 29.94930 ? 29  PHE C O   1 
ATOM   3752 C CB  . PHE C 1 30  ? 66.57939 52.26999 85.12677  1.000 25.61067 ? 29  PHE C CB  1 
ATOM   3753 C CG  . PHE C 1 30  ? 65.44542 53.00458 84.46799  1.000 25.37873 ? 29  PHE C CG  1 
ATOM   3754 C CD1 . PHE C 1 30  ? 65.11741 54.28340 84.84701  1.000 21.65780 ? 29  PHE C CD1 1 
ATOM   3755 C CD2 . PHE C 1 30  ? 64.72503 52.41474 83.44901  1.000 25.69786 ? 29  PHE C CD2 1 
ATOM   3756 C CE1 . PHE C 1 30  ? 64.08854 54.94888 84.22776  1.000 23.12730 ? 29  PHE C CE1 1 
ATOM   3757 C CE2 . PHE C 1 30  ? 63.69168 53.08626 82.82415  1.000 23.36901 ? 29  PHE C CE2 1 
ATOM   3758 C CZ  . PHE C 1 30  ? 63.37562 54.34564 83.21204  1.000 21.94670 ? 29  PHE C CZ  1 
ATOM   3759 N N   . GLY C 1 31  ? 65.69311 49.48181 86.34731  1.000 24.30638 ? 30  GLY C N   1 
ATOM   3760 C CA  . GLY C 1 31  ? 64.72390 48.42715 86.12414  1.000 25.13082 ? 30  GLY C CA  1 
ATOM   3761 C C   . GLY C 1 31  ? 63.87376 48.07086 87.32427  1.000 28.55971 ? 30  GLY C C   1 
ATOM   3762 O O   . GLY C 1 31  ? 62.79936 47.48845 87.14934  1.000 24.19025 ? 30  GLY C O   1 
ATOM   3763 N N   . ASP C 1 32  ? 64.29493 48.43848 88.53379  1.000 29.43860 ? 31  ASP C N   1 
ATOM   3764 C CA  . ASP C 1 32  ? 63.58304 47.98465 89.72345  1.000 26.19439 ? 31  ASP C CA  1 
ATOM   3765 C C   . ASP C 1 32  ? 62.52107 48.95182 90.20254  1.000 28.02733 ? 31  ASP C C   1 
ATOM   3766 O O   . ASP C 1 32  ? 61.89632 48.67836 91.23300  1.000 30.34710 ? 31  ASP C O   1 
ATOM   3767 C CB  . ASP C 1 32  ? 64.53122 47.76938 90.90122  1.000 23.78513 ? 31  ASP C CB  1 
ATOM   3768 C CG  . ASP C 1 32  ? 65.53269 46.69090 90.66431  1.000 31.78742 ? 31  ASP C CG  1 
ATOM   3769 O OD1 . ASP C 1 32  ? 65.23564 45.73564 89.91251  1.000 32.80391 ? 31  ASP C OD1 1 
ATOM   3770 O OD2 . ASP C 1 32  ? 66.63171 46.80777 91.25201  1.000 33.76437 ? 31  ASP C OD2 1 
ATOM   3771 N N   . TYR C 1 33  ? 62.26990 50.04926 89.49635  1.000 27.68168 ? 32  TYR C N   1 
ATOM   3772 C CA  . TYR C 1 33  ? 61.41163 51.09960 90.03581  1.000 27.15545 ? 32  TYR C CA  1 
ATOM   3773 C C   . TYR C 1 33  ? 60.33244 51.43174 89.01911  1.000 30.25241 ? 32  TYR C C   1 
ATOM   3774 O O   . TYR C 1 33  ? 60.63138 51.74468 87.86191  1.000 34.58518 ? 32  TYR C O   1 
ATOM   3775 C CB  . TYR C 1 33  ? 62.19730 52.37974 90.36449  1.000 21.22719 ? 32  TYR C CB  1 
ATOM   3776 C CG  . TYR C 1 33  ? 63.20329 52.31849 91.52594  1.000 29.65269 ? 32  TYR C CG  1 
ATOM   3777 C CD1 . TYR C 1 33  ? 64.55558 52.07942 91.27686  1.000 29.39111 ? 32  TYR C CD1 1 
ATOM   3778 C CD2 . TYR C 1 33  ? 62.81403 52.56264 92.85677  1.000 26.13596 ? 32  TYR C CD2 1 
ATOM   3779 C CE1 . TYR C 1 33  ? 65.48713 52.05212 92.29485  1.000 26.62922 ? 32  TYR C CE1 1 
ATOM   3780 C CE2 . TYR C 1 33  ? 63.74514 52.52944 93.90043  1.000 22.59987 ? 32  TYR C CE2 1 
ATOM   3781 C CZ  . TYR C 1 33  ? 65.08723 52.27416 93.60262  1.000 30.12553 ? 32  TYR C CZ  1 
ATOM   3782 O OH  . TYR C 1 33  ? 66.06138 52.22623 94.58538  1.000 28.48481 ? 32  TYR C OH  1 
ATOM   3783 N N   . ALA C 1 34  ? 59.09044 51.43569 89.47767  1.000 24.95490 ? 33  ALA C N   1 
ATOM   3784 C CA  . ALA C 1 34  ? 57.99822 51.95686 88.68599  1.000 25.40138 ? 33  ALA C CA  1 
ATOM   3785 C C   . ALA C 1 34  ? 58.27767 53.40554 88.28277  1.000 28.79128 ? 33  ALA C C   1 
ATOM   3786 O O   . ALA C 1 34  ? 59.10217 54.10940 88.88353  1.000 26.43949 ? 33  ALA C O   1 
ATOM   3787 C CB  . ALA C 1 34  ? 56.68957 51.86160 89.47136  1.000 23.40480 ? 33  ALA C CB  1 
ATOM   3788 N N   . MET C 1 35  ? 57.62415 53.82822 87.20334  1.000 26.62637 ? 34  MET C N   1 
ATOM   3789 C CA  . MET C 1 35  ? 57.74493 55.18758 86.70327  1.000 22.65979 ? 34  MET C CA  1 
ATOM   3790 C C   . MET C 1 35  ? 56.37058 55.72086 86.38804  1.000 23.13930 ? 34  MET C C   1 
ATOM   3791 O O   . MET C 1 35  ? 55.54959 54.99170 85.83236  1.000 24.96493 ? 34  MET C O   1 
ATOM   3792 C CB  . MET C 1 35  ? 58.58789 55.23932 85.46468  1.000 18.81757 ? 34  MET C CB  1 
ATOM   3793 C CG  . MET C 1 35  ? 60.00378 54.87359 85.77871  1.000 26.02081 ? 34  MET C CG  1 
ATOM   3794 S SD  . MET C 1 35  ? 60.75648 56.31274 86.52883  1.000 26.86524 ? 34  MET C SD  1 
ATOM   3795 C CE  . MET C 1 35  ? 62.35539 55.69580 87.00007  1.000 18.94666 ? 34  MET C CE  1 
ATOM   3796 N N   . SER C 1 36  ? 56.12153 56.98836 86.74436  1.000 23.76475 ? 35  SER C N   1 
ATOM   3797 C CA  . SER C 1 36  ? 54.81655 57.61717 86.56152  1.000 21.71645 ? 35  SER C CA  1 
ATOM   3798 C C   . SER C 1 36  ? 54.97446 58.98121 85.89843  1.000 27.60053 ? 35  SER C C   1 
ATOM   3799 O O   . SER C 1 36  ? 55.93619 59.70797 86.17430  1.000 26.38670 ? 35  SER C O   1 
ATOM   3800 C CB  . SER C 1 36  ? 54.08132 57.76700 87.88709  1.000 21.56425 ? 35  SER C CB  1 
ATOM   3801 O OG  . SER C 1 36  ? 52.71523 58.07810 87.68875  1.000 25.82820 ? 35  SER C OG  1 
ATOM   3802 N N   . TRP C 1 37  ? 54.03884 59.31394 85.00894  1.000 23.13810 ? 36  TRP C N   1 
ATOM   3803 C CA  . TRP C 1 37  ? 53.99944 60.61317 84.34744  1.000 29.64487 ? 36  TRP C CA  1 
ATOM   3804 C C   . TRP C 1 37  ? 52.88194 61.47502 84.92462  1.000 28.21297 ? 36  TRP C C   1 
ATOM   3805 O O   . TRP C 1 37  ? 51.74900 61.00890 85.06397  1.000 26.66213 ? 36  TRP C O   1 
ATOM   3806 C CB  . TRP C 1 37  ? 53.79927 60.46382 82.83947  1.000 28.78073 ? 36  TRP C CB  1 
ATOM   3807 C CG  . TRP C 1 37  ? 54.99835 59.96556 82.12294  1.000 26.37435 ? 36  TRP C CG  1 
ATOM   3808 C CD1 . TRP C 1 37  ? 55.35431 58.67271 81.93912  1.000 26.66507 ? 36  TRP C CD1 1 
ATOM   3809 C CD2 . TRP C 1 37  ? 55.99990 60.76025 81.47225  1.000 26.65480 ? 36  TRP C CD2 1 
ATOM   3810 N NE1 . TRP C 1 37  ? 56.52165 58.60149 81.21211  1.000 26.17425 ? 36  TRP C NE1 1 
ATOM   3811 C CE2 . TRP C 1 37  ? 56.93927 59.86746 80.91459  1.000 21.20049 ? 36  TRP C CE2 1 
ATOM   3812 C CE3 . TRP C 1 37  ? 56.18937 62.14074 81.30783  1.000 23.24973 ? 36  TRP C CE3 1 
ATOM   3813 C CZ2 . TRP C 1 37  ? 58.05091 60.29520 80.21002  1.000 25.10407 ? 36  TRP C CZ2 1 
ATOM   3814 C CZ3 . TRP C 1 37  ? 57.29518 62.57411 80.61056  1.000 30.91100 ? 36  TRP C CZ3 1 
ATOM   3815 C CH2 . TRP C 1 37  ? 58.22170 61.64664 80.06457  1.000 33.51773 ? 36  TRP C CH2 1 
ATOM   3816 N N   . PHE C 1 38  ? 53.20037 62.72871 85.24800  1.000 24.79029 ? 37  PHE C N   1 
ATOM   3817 C CA  . PHE C 1 38  ? 52.22247 63.68414 85.74549  1.000 27.30221 ? 37  PHE C CA  1 
ATOM   3818 C C   . PHE C 1 38  ? 52.26750 64.95918 84.91443  1.000 26.40085 ? 37  PHE C C   1 
ATOM   3819 O O   . PHE C 1 38  ? 53.28380 65.27403 84.29499  1.000 28.01584 ? 37  PHE C O   1 
ATOM   3820 C CB  . PHE C 1 38  ? 52.48158 64.04194 87.21161  1.000 33.12950 ? 37  PHE C CB  1 
ATOM   3821 C CG  . PHE C 1 38  ? 52.37593 62.88468 88.16235  1.000 28.31539 ? 37  PHE C CG  1 
ATOM   3822 C CD1 . PHE C 1 38  ? 51.23738 62.70696 88.92343  1.000 25.99946 ? 37  PHE C CD1 1 
ATOM   3823 C CD2 . PHE C 1 38  ? 53.43391 62.00068 88.32759  1.000 28.20183 ? 37  PHE C CD2 1 
ATOM   3824 C CE1 . PHE C 1 38  ? 51.14670 61.64880 89.81614  1.000 27.78025 ? 37  PHE C CE1 1 
ATOM   3825 C CE2 . PHE C 1 38  ? 53.34167 60.94513 89.21996  1.000 25.55452 ? 37  PHE C CE2 1 
ATOM   3826 C CZ  . PHE C 1 38  ? 52.19672 60.77447 89.96005  1.000 23.66464 ? 37  PHE C CZ  1 
ATOM   3827 N N   . ARG C 1 39  ? 51.17509 65.72575 84.94256  1.000 25.09892 ? 38  ARG C N   1 
ATOM   3828 C CA  . ARG C 1 39  ? 51.13006 66.97988 84.19680  1.000 28.79324 ? 38  ARG C CA  1 
ATOM   3829 C C   . ARG C 1 39  ? 50.51876 68.10870 85.02569  1.000 30.65946 ? 38  ARG C C   1 
ATOM   3830 O O   . ARG C 1 39  ? 49.51787 67.90862 85.71419  1.000 36.18933 ? 38  ARG C O   1 
ATOM   3831 C CB  . ARG C 1 39  ? 50.37125 66.80495 82.86782  1.000 22.97482 ? 38  ARG C CB  1 
ATOM   3832 C CG  . ARG C 1 39  ? 48.86036 66.69553 82.92096  1.000 23.90859 ? 38  ARG C CG  1 
ATOM   3833 C CD  . ARG C 1 39  ? 48.41242 66.36074 81.52162  1.000 26.81939 ? 38  ARG C CD  1 
ATOM   3834 N NE  . ARG C 1 39  ? 46.98114 66.18029 81.31246  1.000 34.77562 ? 38  ARG C NE  1 
ATOM   3835 C CZ  . ARG C 1 39  ? 46.45045 65.81380 80.13728  1.000 44.82426 ? 38  ARG C CZ  1 
ATOM   3836 N NH1 . ARG C 1 39  ? 47.23495 65.61353 79.07536  1.000 35.35274 ? 38  ARG C NH1 1 
ATOM   3837 N NH2 . ARG C 1 39  ? 45.13247 65.66524 80.00212  1.000 41.12615 ? 38  ARG C NH2 1 
ATOM   3838 N N   . LEU C 1 40  ? 51.10707 69.30723 84.93637  1.000 33.48200 ? 39  LEU C N   1 
ATOM   3839 C CA  . LEU C 1 40  ? 50.54969 70.51362 85.55302  1.000 28.30263 ? 39  LEU C CA  1 
ATOM   3840 C C   . LEU C 1 40  ? 49.97940 71.39453 84.45210  1.000 27.41833 ? 39  LEU C C   1 
ATOM   3841 O O   . LEU C 1 40  ? 50.72744 71.91216 83.61616  1.000 27.39647 ? 39  LEU C O   1 
ATOM   3842 C CB  . LEU C 1 40  ? 51.60539 71.29085 86.33732  1.000 27.63633 ? 39  LEU C CB  1 
ATOM   3843 C CG  . LEU C 1 40  ? 51.09726 72.64066 86.83626  1.000 27.08389 ? 39  LEU C CG  1 
ATOM   3844 C CD1 . LEU C 1 40  ? 49.83054 72.47245 87.63854  1.000 27.97778 ? 39  LEU C CD1 1 
ATOM   3845 C CD2 . LEU C 1 40  ? 52.14414 73.32639 87.67169  1.000 27.38289 ? 39  LEU C CD2 1 
ATOM   3846 N N   . ALA C 1 41  ? 48.66562 71.59476 84.47673  1.000 28.46876 ? 40  ALA C N   1 
ATOM   3847 C CA  . ALA C 1 41  ? 47.99190 72.29677 83.39011  1.000 28.60279 ? 40  ALA C CA  1 
ATOM   3848 C C   . ALA C 1 41  ? 47.41757 73.63193 83.86797  1.000 36.47672 ? 40  ALA C C   1 
ATOM   3849 O O   . ALA C 1 41  ? 47.04579 73.78087 85.03933  1.000 31.12280 ? 40  ALA C O   1 
ATOM   3850 C CB  . ALA C 1 41  ? 46.86212 71.45095 82.79663  1.000 25.47956 ? 40  ALA C CB  1 
ATOM   3851 N N   . PRO C 1 42  ? 47.31121 74.61595 82.97142  1.000 31.11256 ? 41  PRO C N   1 
ATOM   3852 C CA  . PRO C 1 42  ? 46.94835 75.96470 83.41999  1.000 35.39351 ? 41  PRO C CA  1 
ATOM   3853 C C   . PRO C 1 42  ? 45.61843 76.04189 84.14198  1.000 36.19470 ? 41  PRO C C   1 
ATOM   3854 O O   . PRO C 1 42  ? 45.53105 76.67947 85.20433  1.000 38.71536 ? 41  PRO C O   1 
ATOM   3855 C CB  . PRO C 1 42  ? 46.92365 76.76443 82.11454  1.000 34.95045 ? 41  PRO C CB  1 
ATOM   3856 C CG  . PRO C 1 42  ? 47.69763 75.97558 81.16506  1.000 35.43153 ? 41  PRO C CG  1 
ATOM   3857 C CD  . PRO C 1 42  ? 47.54431 74.56021 81.52468  1.000 30.51724 ? 41  PRO C CD  1 
ATOM   3858 N N   . GLY C 1 43  ? 44.57777 75.41373 83.62092  1.000 32.29138 ? 42  GLY C N   1 
ATOM   3859 C CA  . GLY C 1 43  ? 43.33106 75.56629 84.33648  1.000 44.75313 ? 42  GLY C CA  1 
ATOM   3860 C C   . GLY C 1 43  ? 43.30094 74.84669 85.66936  1.000 43.82991 ? 42  GLY C C   1 
ATOM   3861 O O   . GLY C 1 43  ? 43.23820 75.48834 86.72516  1.000 34.20675 ? 42  GLY C O   1 
ATOM   3862 N N   . LYS C 1 44  ? 43.43766 73.51947 85.61128  1.000 47.28218 ? 43  LYS C N   1 
ATOM   3863 C CA  . LYS C 1 44  ? 43.44655 72.61975 86.75971  1.000 46.20019 ? 43  LYS C CA  1 
ATOM   3864 C C   . LYS C 1 44  ? 44.72699 72.76085 87.58649  1.000 45.42294 ? 43  LYS C C   1 
ATOM   3865 O O   . LYS C 1 44  ? 45.55685 73.65045 87.37731  1.000 45.43432 ? 43  LYS C O   1 
ATOM   3866 C CB  . LYS C 1 44  ? 43.26342 71.17601 86.29641  1.000 43.96442 ? 43  LYS C CB  1 
ATOM   3867 N N   . GLY C 1 45  ? 44.84389 71.89375 88.58985  1.000 42.27448 ? 44  GLY C N   1 
ATOM   3868 C CA  . GLY C 1 45  ? 46.05802 71.79226 89.36955  1.000 40.08090 ? 44  GLY C CA  1 
ATOM   3869 C C   . GLY C 1 45  ? 46.94252 70.71445 88.77233  1.000 41.23582 ? 44  GLY C C   1 
ATOM   3870 O O   . GLY C 1 45  ? 47.12323 70.68837 87.55292  1.000 37.59297 ? 44  GLY C O   1 
ATOM   3871 N N   . LEU C 1 46  ? 47.47092 69.80849 89.59963  1.000 34.37507 ? 45  LEU C N   1 
ATOM   3872 C CA  . LEU C 1 46  ? 48.26878 68.68380 89.13271  1.000 26.24203 ? 45  LEU C CA  1 
ATOM   3873 C C   . LEU C 1 46  ? 47.38643 67.49407 88.79773  1.000 30.15193 ? 45  LEU C C   1 
ATOM   3874 O O   . LEU C 1 46  ? 46.32035 67.30287 89.38371  1.000 37.30538 ? 45  LEU C O   1 
ATOM   3875 C CB  . LEU C 1 46  ? 49.27902 68.28530 90.19721  1.000 22.46673 ? 45  LEU C CB  1 
ATOM   3876 C CG  . LEU C 1 46  ? 50.54757 69.10057 90.06737  1.000 26.47043 ? 45  LEU C CG  1 
ATOM   3877 C CD1 . LEU C 1 46  ? 51.52570 68.86129 91.21012  1.000 24.20369 ? 45  LEU C CD1 1 
ATOM   3878 C CD2 . LEU C 1 46  ? 51.16671 68.72250 88.74398  1.000 36.89312 ? 45  LEU C CD2 1 
ATOM   3879 N N   . GLU C 1 47  ? 47.83793 66.69231 87.83814  1.000 29.99875 ? 46  GLU C N   1 
ATOM   3880 C CA  . GLU C 1 47  ? 47.11460 65.49869 87.41191  1.000 32.58283 ? 46  GLU C CA  1 
ATOM   3881 C C   . GLU C 1 47  ? 48.08039 64.33689 87.23055  1.000 29.50788 ? 46  GLU C C   1 
ATOM   3882 O O   . GLU C 1 47  ? 49.17783 64.51050 86.68746  1.000 27.73279 ? 46  GLU C O   1 
ATOM   3883 C CB  . GLU C 1 47  ? 46.38550 65.72123 86.08349  1.000 30.98151 ? 46  GLU C CB  1 
ATOM   3884 C CG  . GLU C 1 47  ? 45.68900 67.04572 85.95226  1.000 44.62299 ? 46  GLU C CG  1 
ATOM   3885 C CD  . GLU C 1 47  ? 45.00352 67.19137 84.60929  1.000 58.70918 ? 46  GLU C CD  1 
ATOM   3886 O OE1 . GLU C 1 47  ? 45.67743 67.58254 83.62417  1.000 63.65680 ? 46  GLU C OE1 1 
ATOM   3887 O OE2 . GLU C 1 47  ? 43.79136 66.88602 84.53950  1.000 68.35143 ? 46  GLU C OE2 1 
ATOM   3888 N N   . TRP C 1 48  ? 47.65819 63.14860 87.65017  1.000 25.88618 ? 47  TRP C N   1 
ATOM   3889 C CA  . TRP C 1 48  ? 48.37152 61.93704 87.27433  1.000 23.62888 ? 47  TRP C CA  1 
ATOM   3890 C C   . TRP C 1 48  ? 48.05184 61.61146 85.82004  1.000 21.53915 ? 47  TRP C C   1 
ATOM   3891 O O   . TRP C 1 48  ? 46.88878 61.66595 85.41192  1.000 23.62688 ? 47  TRP C O   1 
ATOM   3892 C CB  . TRP C 1 48  ? 47.96250 60.78164 88.18724  1.000 27.50538 ? 47  TRP C CB  1 
ATOM   3893 C CG  . TRP C 1 48  ? 48.41256 59.42580 87.72100  1.000 22.54659 ? 47  TRP C CG  1 
ATOM   3894 C CD1 . TRP C 1 48  ? 49.69630 58.95717 87.66155  1.000 22.78629 ? 47  TRP C CD1 1 
ATOM   3895 C CD2 . TRP C 1 48  ? 47.57798 58.36582 87.26306  1.000 24.34867 ? 47  TRP C CD2 1 
ATOM   3896 N NE1 . TRP C 1 48  ? 49.71161 57.67481 87.18937  1.000 23.01781 ? 47  TRP C NE1 1 
ATOM   3897 C CE2 . TRP C 1 48  ? 48.42073 57.28592 86.93396  1.000 27.93589 ? 47  TRP C CE2 1 
ATOM   3898 C CE3 . TRP C 1 48  ? 46.19474 58.22195 87.09194  1.000 27.57558 ? 47  TRP C CE3 1 
ATOM   3899 C CZ2 . TRP C 1 48  ? 47.92599 56.08096 86.43918  1.000 23.99194 ? 47  TRP C CZ2 1 
ATOM   3900 C CZ3 . TRP C 1 48  ? 45.70678 57.01915 86.59864  1.000 23.55703 ? 47  TRP C CZ3 1 
ATOM   3901 C CH2 . TRP C 1 48  ? 46.57098 55.97098 86.27844  1.000 23.34348 ? 47  TRP C CH2 1 
ATOM   3902 N N   . VAL C 1 49  ? 49.07434 61.27344 85.03580  1.000 19.34999 ? 48  VAL C N   1 
ATOM   3903 C CA  . VAL C 1 49  ? 48.86768 60.92266 83.63290  1.000 20.82230 ? 48  VAL C CA  1 
ATOM   3904 C C   . VAL C 1 49  ? 48.91688 59.40692 83.45106  1.000 24.24956 ? 48  VAL C C   1 
ATOM   3905 O O   . VAL C 1 49  ? 47.96406 58.80132 82.95404  1.000 22.64873 ? 48  VAL C O   1 
ATOM   3906 C CB  . VAL C 1 49  ? 49.89174 61.62560 82.73483  1.000 22.25705 ? 48  VAL C CB  1 
ATOM   3907 C CG1 . VAL C 1 49  ? 49.90967 60.99478 81.36171  1.000 26.00981 ? 48  VAL C CG1 1 
ATOM   3908 C CG2 . VAL C 1 49  ? 49.56067 63.10496 82.65501  1.000 24.03278 ? 48  VAL C CG2 1 
ATOM   3909 N N   . GLY C 1 50  ? 50.00094 58.77193 83.87383  1.000 27.15144 ? 49  GLY C N   1 
ATOM   3910 C CA  . GLY C 1 50  ? 50.05448 57.33156 83.70908  1.000 28.04879 ? 49  GLY C CA  1 
ATOM   3911 C C   . GLY C 1 50  ? 51.15726 56.71715 84.53927  1.000 28.01967 ? 49  GLY C C   1 
ATOM   3912 O O   . GLY C 1 50  ? 51.92134 57.41749 85.21064  1.000 27.39582 ? 49  GLY C O   1 
ATOM   3913 N N   . LEU C 1 51  ? 51.21365 55.37845 84.48948  1.000 28.63231 ? 50  LEU C N   1 
ATOM   3914 C CA  . LEU C 1 51  ? 52.12520 54.60053 85.31610  1.000 21.83820 ? 50  LEU C CA  1 
ATOM   3915 C C   . LEU C 1 51  ? 52.60384 53.39384 84.52957  1.000 20.14514 ? 50  LEU C C   1 
ATOM   3916 O O   . LEU C 1 51  ? 51.81678 52.78055 83.81866  1.000 20.57584 ? 50  LEU C O   1 
ATOM   3917 C CB  . LEU C 1 51  ? 51.44695 54.15303 86.60292  1.000 21.13295 ? 50  LEU C CB  1 
ATOM   3918 C CG  . LEU C 1 51  ? 52.31567 53.51811 87.68675  1.000 23.66261 ? 50  LEU C CG  1 
ATOM   3919 C CD1 . LEU C 1 51  ? 53.60145 54.26449 87.94623  1.000 24.92059 ? 50  LEU C CD1 1 
ATOM   3920 C CD2 . LEU C 1 51  ? 51.53201 53.45028 88.94476  1.000 24.80584 ? 50  LEU C CD2 1 
ATOM   3921 N N   . ILE C 1 52  ? 53.90600 53.11395 84.59022  1.000 20.56793 ? 51  ILE C N   1 
ATOM   3922 C CA  . ILE C 1 52  ? 54.46897 51.85260 84.11462  1.000 26.13659 ? 51  ILE C CA  1 
ATOM   3923 C C   . ILE C 1 52  ? 55.25551 51.20843 85.25948  1.000 25.89248 ? 51  ILE C C   1 
ATOM   3924 O O   . ILE C 1 52  ? 56.04677 51.87076 85.94358  1.000 21.82296 ? 51  ILE C O   1 
ATOM   3925 C CB  . ILE C 1 52  ? 55.34275 52.00242 82.84595  1.000 20.88798 ? 51  ILE C CB  1 
ATOM   3926 C CG1 . ILE C 1 52  ? 55.51168 50.63786 82.17085  1.000 23.77671 ? 51  ILE C CG1 1 
ATOM   3927 C CG2 . ILE C 1 52  ? 56.75011 52.45610 83.13945  1.000 22.18210 ? 51  ILE C CG2 1 
ATOM   3928 C CD1 . ILE C 1 52  ? 56.15734 50.68611 80.80214  1.000 19.34531 ? 51  ILE C CD1 1 
ATOM   3929 N N   . LYS C 1 53  ? 55.02297 49.92344 85.47758  1.000 24.12609 ? 52  LYS C N   1 
ATOM   3930 C CA  . LYS C 1 53  ? 55.67782 49.26096 86.58191  1.000 24.62889 ? 52  LYS C CA  1 
ATOM   3931 C C   . LYS C 1 53  ? 57.02391 48.69264 86.14013  1.000 28.29368 ? 52  LYS C C   1 
ATOM   3932 O O   . LYS C 1 53  ? 57.41534 48.74422 84.96689  1.000 24.51586 ? 52  LYS C O   1 
ATOM   3933 C CB  . LYS C 1 53  ? 54.80358 48.14258 87.13047  1.000 34.44605 ? 52  LYS C CB  1 
ATOM   3934 C CG  . LYS C 1 53  ? 53.42807 48.55192 87.61865  1.000 33.29466 ? 52  LYS C CG  1 
ATOM   3935 C CD  . LYS C 1 53  ? 52.57844 47.30304 87.66098  1.000 39.07810 ? 52  LYS C CD  1 
ATOM   3936 C CE  . LYS C 1 53  ? 51.20941 47.51022 88.26487  1.000 48.33832 ? 52  LYS C CE  1 
ATOM   3937 N NZ  . LYS C 1 53  ? 50.28469 46.48784 87.66335  1.000 47.27757 ? 52  LYS C NZ  1 
ATOM   3938 N N   . SER C 1 54  ? 57.74917 48.16431 87.11515  1.000 27.92567 ? 53  SER C N   1 
ATOM   3939 C CA  . SER C 1 54  ? 58.94421 47.41126 86.80586  1.000 26.51942 ? 53  SER C CA  1 
ATOM   3940 C C   . SER C 1 54  ? 58.54541 46.15338 86.05866  1.000 32.89163 ? 53  SER C C   1 
ATOM   3941 O O   . SER C 1 54  ? 57.46809 45.59967 86.28754  1.000 32.93478 ? 53  SER C O   1 
ATOM   3942 C CB  . SER C 1 54  ? 59.67604 47.03857 88.08244  1.000 26.01301 ? 53  SER C CB  1 
ATOM   3943 O OG  . SER C 1 54  ? 61.00366 46.69967 87.77232  1.000 31.78918 ? 53  SER C OG  1 
ATOM   3944 N N   . ARG C 1 55  ? 59.40424 45.72019 85.12872  1.000 34.04008 ? 54  ARG C N   1 
ATOM   3945 C CA  . ARG C 1 55  ? 59.11424 44.49314 84.39764  1.000 24.06111 ? 54  ARG C CA  1 
ATOM   3946 C C   . ARG C 1 55  ? 59.05710 43.30106 85.33521  1.000 25.85740 ? 54  ARG C C   1 
ATOM   3947 O O   . ARG C 1 55  ? 58.39958 42.31196 85.01072  1.000 27.91666 ? 54  ARG C O   1 
ATOM   3948 C CB  . ARG C 1 55  ? 60.14476 44.25598 83.29417  1.000 22.49692 ? 54  ARG C CB  1 
ATOM   3949 N N   . ALA C 1 56  ? 59.66537 43.40670 86.53403  1.000 26.54358 ? 55  ALA C N   1 
ATOM   3950 C CA  . ALA C 1 56  ? 59.56929 42.33675 87.50853  1.000 25.28121 ? 55  ALA C CA  1 
ATOM   3951 C C   . ALA C 1 56  ? 58.19610 42.22859 88.13875  1.000 29.61659 ? 55  ALA C C   1 
ATOM   3952 O O   . ALA C 1 56  ? 57.94611 41.41476 89.02347  1.000 38.19774 ? 55  ALA C O   1 
ATOM   3953 C CB  . ALA C 1 56  ? 60.62538 42.54749 88.59178  1.000 26.33309 ? 55  ALA C CB  1 
ATOM   3954 N N   . ILE C 1 57  ? 57.25246 43.00675 87.63626  1.000 29.69214 ? 56  ILE C N   1 
ATOM   3955 C CA  . ILE C 1 57  ? 55.86556 43.00474 88.07524  1.000 33.20953 ? 56  ILE C CA  1 
ATOM   3956 C C   . ILE C 1 57  ? 55.04045 43.28764 86.82538  1.000 45.59522 ? 56  ILE C C   1 
ATOM   3957 O O   . ILE C 1 57  ? 54.13010 42.52638 86.47307  1.000 44.84989 ? 56  ILE C O   1 
ATOM   3958 C CB  . ILE C 1 57  ? 55.61603 44.05639 89.17307  1.000 27.82210 ? 56  ILE C CB  1 
ATOM   3959 C CG1 . ILE C 1 57  ? 56.01768 43.51082 90.54097  1.000 33.29924 ? 56  ILE C CG1 1 
ATOM   3960 C CG2 . ILE C 1 57  ? 54.16564 44.47709 89.19192  1.000 32.34620 ? 56  ILE C CG2 1 
ATOM   3961 C CD1 . ILE C 1 57  ? 55.72840 44.44869 91.68690  1.000 25.78467 ? 56  ILE C CD1 1 
ATOM   3962 N N   . ASP C 1 58  ? 55.40547 44.38634 86.14063  1.000 46.57666 ? 57  ASP C N   1 
ATOM   3963 C CA  . ASP C 1 58  ? 54.87621 44.87529 84.86806  1.000 42.59621 ? 57  ASP C CA  1 
ATOM   3964 C C   . ASP C 1 58  ? 53.42144 44.52986 84.62786  1.000 52.49759 ? 57  ASP C C   1 
ATOM   3965 O O   . ASP C 1 58  ? 52.52583 44.96469 85.36034  1.000 51.22656 ? 57  ASP C O   1 
ATOM   3966 C CB  . ASP C 1 58  ? 55.70997 44.33374 83.70120  1.000 44.12567 ? 57  ASP C CB  1 
ATOM   3967 N N   . GLY C 1 59  ? 53.19192 43.74201 83.58998  1.000 61.70458 ? 58  GLY C N   1 
ATOM   3968 C CA  . GLY C 1 59  ? 51.84605 43.46673 83.16130  1.000 66.70033 ? 58  GLY C CA  1 
ATOM   3969 C C   . GLY C 1 59  ? 51.49521 44.41326 82.03445  1.000 66.47461 ? 58  GLY C C   1 
ATOM   3970 O O   . GLY C 1 59  ? 51.80300 44.14252 80.86751  1.000 71.12507 ? 58  GLY C O   1 
ATOM   3971 N N   . THR C 1 60  ? 50.91449 45.56520 82.39021  1.000 52.89313 ? 59  THR C N   1 
ATOM   3972 C CA  . THR C 1 60  ? 50.46488 46.57869 81.44356  1.000 45.30490 ? 59  THR C CA  1 
ATOM   3973 C C   . THR C 1 60  ? 50.34094 47.93355 82.12532  1.000 48.21709 ? 59  THR C C   1 
ATOM   3974 O O   . THR C 1 60  ? 49.87535 47.99125 83.27644  1.000 50.85991 ? 59  THR C O   1 
ATOM   3975 C CB  . THR C 1 60  ? 49.11612 46.19065 80.82428  1.000 49.82629 ? 59  THR C CB  1 
ATOM   3976 O OG1 . THR C 1 60  ? 48.22339 45.73978 81.85620  1.000 49.38392 ? 59  THR C OG1 1 
ATOM   3977 C CG2 . THR C 1 60  ? 49.26968 45.14027 79.70862  1.000 52.82984 ? 59  THR C CG2 1 
ATOM   3978 N N   . PRO C 1 61  ? 50.78910 49.02193 81.49177  1.000 39.78514 ? 60  PRO C N   1 
ATOM   3979 C CA  . PRO C 1 61  ? 50.70077 50.33367 82.12962  1.000 24.96947 ? 60  PRO C CA  1 
ATOM   3980 C C   . PRO C 1 61  ? 49.25730 50.75232 82.30168  1.000 26.59424 ? 60  PRO C C   1 
ATOM   3981 O O   . PRO C 1 61  ? 48.37925 50.38055 81.52147  1.000 34.22029 ? 60  PRO C O   1 
ATOM   3982 C CB  . PRO C 1 61  ? 51.40605 51.24760 81.13126  1.000 28.98560 ? 60  PRO C CB  1 
ATOM   3983 C CG  . PRO C 1 61  ? 52.18446 50.32241 80.25879  1.000 23.84790 ? 60  PRO C CG  1 
ATOM   3984 C CD  . PRO C 1 61  ? 51.35290 49.13614 80.13978  1.000 26.78164 ? 60  PRO C CD  1 
ATOM   3985 N N   . GLN C 1 62  ? 49.01362 51.52626 83.34644  1.000 28.02260 ? 61  GLN C N   1 
ATOM   3986 C CA  . GLN C 1 62  ? 47.69309 52.05986 83.63006  1.000 29.18073 ? 61  GLN C CA  1 
ATOM   3987 C C   . GLN C 1 62  ? 47.70901 53.54666 83.32083  1.000 27.41240 ? 61  GLN C C   1 
ATOM   3988 O O   . GLN C 1 62  ? 48.70515 54.23428 83.57420  1.000 24.18497 ? 61  GLN C O   1 
ATOM   3989 C CB  . GLN C 1 62  ? 47.28110 51.81230 85.08163  1.000 44.79283 ? 61  GLN C CB  1 
ATOM   3990 N N   . TYR C 1 63  ? 46.62180 54.01819 82.73341  1.000 25.72831 ? 62  TYR C N   1 
ATOM   3991 C CA  . TYR C 1 63  ? 46.47881 55.40184 82.34376  1.000 26.73244 ? 62  TYR C CA  1 
ATOM   3992 C C   . TYR C 1 63  ? 45.30770 56.02218 83.08968  1.000 30.08396 ? 62  TYR C C   1 
ATOM   3993 O O   . TYR C 1 63  ? 44.58019 55.35386 83.82935  1.000 32.22642 ? 62  TYR C O   1 
ATOM   3994 C CB  . TYR C 1 63  ? 46.31233 55.50130 80.82119  1.000 30.65572 ? 62  TYR C CB  1 
ATOM   3995 C CG  . TYR C 1 63  ? 47.47448 54.86811 80.10081  1.000 24.76788 ? 62  TYR C CG  1 
ATOM   3996 C CD1 . TYR C 1 63  ? 47.40252 53.57272 79.60046  1.000 28.57693 ? 62  TYR C CD1 1 
ATOM   3997 C CD2 . TYR C 1 63  ? 48.66520 55.53370 79.99030  1.000 22.60731 ? 62  TYR C CD2 1 
ATOM   3998 C CE1 . TYR C 1 63  ? 48.48934 52.98552 78.97258  1.000 24.33768 ? 62  TYR C CE1 1 
ATOM   3999 C CE2 . TYR C 1 63  ? 49.74874 54.95403 79.38184  1.000 28.15695 ? 62  TYR C CE2 1 
ATOM   4000 C CZ  . TYR C 1 63  ? 49.66145 53.68893 78.87253  1.000 24.12045 ? 62  TYR C CZ  1 
ATOM   4001 O OH  . TYR C 1 63  ? 50.76878 53.16238 78.26174  1.000 24.49385 ? 62  TYR C OH  1 
ATOM   4002 N N   . ALA C 1 64  ? 45.06912 57.29125 82.80447  1.000 29.18641 ? 63  ALA C N   1 
ATOM   4003 C CA  . ALA C 1 64  ? 44.02999 58.05160 83.47243  1.000 30.44865 ? 63  ALA C CA  1 
ATOM   4004 C C   . ALA C 1 64  ? 42.83827 58.16446 82.53580  1.000 33.83104 ? 63  ALA C C   1 
ATOM   4005 O O   . ALA C 1 64  ? 43.00523 58.19252 81.31483  1.000 36.31817 ? 63  ALA C O   1 
ATOM   4006 C CB  . ALA C 1 64  ? 44.54352 59.43800 83.85001  1.000 30.02724 ? 63  ALA C CB  1 
ATOM   4007 N N   . ALA C 1 65  ? 41.63776 58.15039 83.11224  1.000 28.46041 ? 64  ALA C N   1 
ATOM   4008 C CA  . ALA C 1 65  ? 40.40256 58.14712 82.34054  1.000 32.08518 ? 64  ALA C CA  1 
ATOM   4009 C C   . ALA C 1 65  ? 40.49735 58.91643 81.02024  1.000 34.59909 ? 64  ALA C C   1 
ATOM   4010 O O   . ALA C 1 65  ? 40.38771 58.31798 79.94569  1.000 36.76266 ? 64  ALA C O   1 
ATOM   4011 C CB  . ALA C 1 65  ? 39.27878 58.71335 83.20783  1.000 37.30724 ? 64  ALA C CB  1 
ATOM   4012 N N   . SER C 1 66  ? 40.74212 60.23086 81.10115  1.000 33.70488 ? 65  SER C N   1 
ATOM   4013 C CA  . SER C 1 66  ? 40.89834 61.14782 79.96327  1.000 39.96338 ? 65  SER C CA  1 
ATOM   4014 C C   . SER C 1 66  ? 42.03155 60.77901 79.01253  1.000 42.28526 ? 65  SER C C   1 
ATOM   4015 O O   . SER C 1 66  ? 42.12451 61.36717 77.92551  1.000 36.25341 ? 65  SER C O   1 
ATOM   4016 C CB  . SER C 1 66  ? 41.13083 62.58138 80.46297  1.000 30.87475 ? 65  SER C CB  1 
ATOM   4017 N N   . VAL C 1 67  ? 42.94138 59.90619 79.43841  1.000 41.60411 ? 66  VAL C N   1 
ATOM   4018 C CA  . VAL C 1 67  ? 44.18107 59.63355 78.71801  1.000 34.22027 ? 66  VAL C CA  1 
ATOM   4019 C C   . VAL C 1 67  ? 44.14460 58.36536 77.86176  1.000 35.04475 ? 66  VAL C C   1 
ATOM   4020 O O   . VAL C 1 67  ? 44.91064 58.26764 76.88787  1.000 26.33850 ? 66  VAL C O   1 
ATOM   4021 C CB  . VAL C 1 67  ? 45.30590 59.57675 79.77478  1.000 34.65784 ? 66  VAL C CB  1 
ATOM   4022 C CG1 . VAL C 1 67  ? 46.63886 59.35318 79.19126  1.000 27.99280 ? 66  VAL C CG1 1 
ATOM   4023 C CG2 . VAL C 1 67  ? 45.28827 60.85975 80.61553  1.000 35.29365 ? 66  VAL C CG2 1 
ATOM   4024 N N   . LYS C 1 68  ? 43.23910 57.42978 78.15508  1.000 38.11069 ? 67  LYS C N   1 
ATOM   4025 C CA  . LYS C 1 68  ? 43.26510 56.09621 77.56755  1.000 39.52934 ? 67  LYS C CA  1 
ATOM   4026 C C   . LYS C 1 68  ? 43.05080 56.17712 76.06319  1.000 45.49198 ? 67  LYS C C   1 
ATOM   4027 O O   . LYS C 1 68  ? 42.34773 57.05646 75.56023  1.000 53.27171 ? 67  LYS C O   1 
ATOM   4028 C CB  . LYS C 1 68  ? 42.19914 55.18774 78.18522  1.000 36.35046 ? 67  LYS C CB  1 
ATOM   4029 C CG  . LYS C 1 68  ? 42.41765 54.76230 79.64291  1.000 35.25775 ? 67  LYS C CG  1 
ATOM   4030 C CD  . LYS C 1 68  ? 43.35069 53.53862 79.79017  1.000 47.79575 ? 67  LYS C CD  1 
ATOM   4031 C CE  . LYS C 1 68  ? 43.47795 53.10114 81.27355  1.000 52.42750 ? 67  LYS C CE  1 
ATOM   4032 N NZ  . LYS C 1 68  ? 44.42849 51.96572 81.55326  1.000 40.73863 ? 67  LYS C NZ  1 
ATOM   4033 N N   . GLY C 1 69  ? 43.77159 55.31606 75.33638  1.000 35.54430 ? 68  GLY C N   1 
ATOM   4034 C CA  . GLY C 1 69  ? 43.62311 55.17877 73.90600  1.000 27.27034 ? 68  GLY C CA  1 
ATOM   4035 C C   . GLY C 1 69  ? 44.34885 56.21147 73.09024  1.000 34.90602 ? 68  GLY C C   1 
ATOM   4036 O O   . GLY C 1 69  ? 44.46808 56.03847 71.87324  1.000 37.47012 ? 68  GLY C O   1 
ATOM   4037 N N   . ARG C 1 70  ? 44.81598 57.29366 73.69938  1.000 34.94310 ? 69  ARG C N   1 
ATOM   4038 C CA  . ARG C 1 70  ? 45.61697 58.26338 72.98449  1.000 32.93552 ? 69  ARG C CA  1 
ATOM   4039 C C   . ARG C 1 70  ? 47.03438 58.30526 73.48894  1.000 34.77055 ? 69  ARG C C   1 
ATOM   4040 O O   . ARG C 1 70  ? 47.95932 58.45788 72.68962  1.000 36.79346 ? 69  ARG C O   1 
ATOM   4041 C CB  . ARG C 1 70  ? 45.05494 59.68989 73.13648  1.000 33.97977 ? 69  ARG C CB  1 
ATOM   4042 C CG  . ARG C 1 70  ? 44.10946 60.18180 72.07641  1.000 36.62900 ? 69  ARG C CG  1 
ATOM   4043 C CD  . ARG C 1 70  ? 43.67290 61.61132 72.39199  1.000 37.42007 ? 69  ARG C CD  1 
ATOM   4044 N NE  . ARG C 1 70  ? 43.57924 61.85246 73.83393  1.000 40.72227 ? 69  ARG C NE  1 
ATOM   4045 C CZ  . ARG C 1 70  ? 43.99979 62.95845 74.44503  1.000 30.90503 ? 69  ARG C CZ  1 
ATOM   4046 N NH1 . ARG C 1 70  ? 44.57017 63.93808 73.76447  1.000 30.72104 ? 69  ARG C NH1 1 
ATOM   4047 N NH2 . ARG C 1 70  ? 43.86483 63.07470 75.74782  1.000 33.26654 ? 69  ARG C NH2 1 
ATOM   4048 N N   . PHE C 1 71  ? 47.23133 58.07912 74.77674  1.000 32.73321 ? 70  PHE C N   1 
ATOM   4049 C CA  . PHE C 1 71  ? 48.54917 58.08987 75.37598  1.000 32.73662 ? 70  PHE C CA  1 
ATOM   4050 C C   . PHE C 1 71  ? 48.99751 56.65978 75.60253  1.000 29.20927 ? 70  PHE C C   1 
ATOM   4051 O O   . PHE C 1 71  ? 48.18630 55.76530 75.85269  1.000 28.25218 ? 70  PHE C O   1 
ATOM   4052 C CB  . PHE C 1 71  ? 48.49613 58.84417 76.69429  1.000 35.98225 ? 70  PHE C CB  1 
ATOM   4053 C CG  . PHE C 1 71  ? 48.40392 60.34642 76.55309  1.000 35.88165 ? 70  PHE C CG  1 
ATOM   4054 C CD1 . PHE C 1 71  ? 49.16296 61.17495 77.35964  1.000 33.75120 ? 70  PHE C CD1 1 
ATOM   4055 C CD2 . PHE C 1 71  ? 47.59268 60.92264 75.59130  1.000 35.38412 ? 70  PHE C CD2 1 
ATOM   4056 C CE1 . PHE C 1 71  ? 49.07630 62.53868 77.24518  1.000 33.24817 ? 70  PHE C CE1 1 
ATOM   4057 C CE2 . PHE C 1 71  ? 47.50977 62.29613 75.45947  1.000 38.40539 ? 70  PHE C CE2 1 
ATOM   4058 C CZ  . PHE C 1 71  ? 48.25432 63.10614 76.28338  1.000 38.37577 ? 70  PHE C CZ  1 
ATOM   4059 N N   . THR C 1 72  ? 50.30237 56.45908 75.53420  1.000 24.01816 ? 71  THR C N   1 
ATOM   4060 C CA  . THR C 1 72  ? 50.85336 55.12135 75.61200  1.000 21.61207 ? 71  THR C CA  1 
ATOM   4061 C C   . THR C 1 72  ? 52.22043 55.25488 76.27250  1.000 24.94888 ? 71  THR C C   1 
ATOM   4062 O O   . THR C 1 72  ? 53.08134 56.00027 75.79748  1.000 26.51298 ? 71  THR C O   1 
ATOM   4063 C CB  . THR C 1 72  ? 50.89398 54.49606 74.18942  1.000 20.18277 ? 71  THR C CB  1 
ATOM   4064 O OG1 . THR C 1 72  ? 50.91771 53.07549 74.25206  1.000 28.08526 ? 71  THR C OG1 1 
ATOM   4065 C CG2 . THR C 1 72  ? 52.09787 54.93203 73.37290  1.000 24.28091 ? 71  THR C CG2 1 
ATOM   4066 N N   . ILE C 1 73  ? 52.40706 54.59519 77.40490  1.000 21.93918 ? 72  ILE C N   1 
ATOM   4067 C CA  . ILE C 1 73  ? 53.64266 54.72416 78.16659  1.000 22.46357 ? 72  ILE C CA  1 
ATOM   4068 C C   . ILE C 1 73  ? 54.45575 53.45276 77.98930  1.000 25.27177 ? 72  ILE C C   1 
ATOM   4069 O O   . ILE C 1 73  ? 53.91712 52.35263 77.82759  1.000 26.04283 ? 72  ILE C O   1 
ATOM   4070 C CB  . ILE C 1 73  ? 53.36459 55.02134 79.65357  1.000 27.20515 ? 72  ILE C CB  1 
ATOM   4071 C CG1 . ILE C 1 73  ? 53.10967 56.51728 79.84044  1.000 28.47550 ? 72  ILE C CG1 1 
ATOM   4072 C CG2 . ILE C 1 73  ? 54.52288 54.59734 80.52611  1.000 22.04409 ? 72  ILE C CG2 1 
ATOM   4073 C CD1 . ILE C 1 73  ? 52.33237 56.84551 81.08157  1.000 24.20976 ? 72  ILE C CD1 1 
ATOM   4074 N N   . SER C 1 74  ? 55.76637 53.61838 77.97030  1.000 24.07667 ? 73  SER C N   1 
ATOM   4075 C CA  . SER C 1 74  ? 56.67768 52.52802 77.69484  1.000 22.18222 ? 73  SER C CA  1 
ATOM   4076 C C   . SER C 1 74  ? 58.00982 52.86446 78.34839  1.000 24.54221 ? 73  SER C C   1 
ATOM   4077 O O   . SER C 1 74  ? 58.24433 53.98861 78.79905  1.000 26.27834 ? 73  SER C O   1 
ATOM   4078 C CB  . SER C 1 74  ? 56.79185 52.28424 76.19874  1.000 20.17786 ? 73  SER C CB  1 
ATOM   4079 O OG  . SER C 1 74  ? 57.63039 53.25449 75.60611  1.000 32.74706 ? 73  SER C OG  1 
ATOM   4080 N N   . ARG C 1 75  ? 58.87191 51.86735 78.42088  1.000 18.87659 ? 74  ARG C N   1 
ATOM   4081 C CA  . ARG C 1 75  ? 60.10314 51.96037 79.17925  1.000 20.50488 ? 74  ARG C CA  1 
ATOM   4082 C C   . ARG C 1 75  ? 61.22963 51.36982 78.34390  1.000 26.80283 ? 74  ARG C C   1 
ATOM   4083 O O   . ARG C 1 75  ? 60.98541 50.64291 77.37875  1.000 27.05342 ? 74  ARG C O   1 
ATOM   4084 C CB  . ARG C 1 75  ? 59.87077 51.24466 80.52155  1.000 26.35085 ? 74  ARG C CB  1 
ATOM   4085 C CG  . ARG C 1 75  ? 61.02314 50.87657 81.39326  1.000 25.05258 ? 74  ARG C CG  1 
ATOM   4086 C CD  . ARG C 1 75  ? 60.51252 49.78618 82.32167  1.000 20.75337 ? 74  ARG C CD  1 
ATOM   4087 N NE  . ARG C 1 75  ? 60.03366 50.25151 83.61455  1.000 17.29925 ? 74  ARG C NE  1 
ATOM   4088 C CZ  . ARG C 1 75  ? 60.83377 50.62685 84.59712  1.000 18.57223 ? 74  ARG C CZ  1 
ATOM   4089 N NH1 . ARG C 1 75  ? 62.13648 50.60977 84.42236  1.000 23.07878 ? 74  ARG C NH1 1 
ATOM   4090 N NH2 . ARG C 1 75  ? 60.33664 51.00901 85.75601  1.000 22.82483 ? 74  ARG C NH2 1 
ATOM   4091 N N   . ASP C 1 76  ? 62.46804 51.75196 78.65834  1.000 24.53934 ? 75  ASP C N   1 
ATOM   4092 C CA  . ASP C 1 76  ? 63.64957 51.10518 78.07368  1.000 21.58540 ? 75  ASP C CA  1 
ATOM   4093 C C   . ASP C 1 76  ? 64.67629 50.92084 79.18475  1.000 25.14147 ? 75  ASP C C   1 
ATOM   4094 O O   . ASP C 1 76  ? 65.36108 51.88703 79.52700  1.000 27.62260 ? 75  ASP C O   1 
ATOM   4095 C CB  . ASP C 1 76  ? 64.23831 51.89948 76.91279  1.000 26.22382 ? 75  ASP C CB  1 
ATOM   4096 C CG  . ASP C 1 76  ? 65.58226 51.32223 76.41061  1.000 37.51171 ? 75  ASP C CG  1 
ATOM   4097 O OD1 . ASP C 1 76  ? 66.37732 50.74155 77.19402  1.000 37.49994 ? 75  ASP C OD1 1 
ATOM   4098 O OD2 . ASP C 1 76  ? 65.84120 51.44340 75.19751  1.000 39.05670 ? 75  ASP C OD2 1 
ATOM   4099 N N   . ASP C 1 77  ? 64.79512 49.69609 79.73050  1.000 32.00023 ? 76  ASP C N   1 
ATOM   4100 C CA  . ASP C 1 77  ? 65.67564 49.47578 80.88789  1.000 27.63258 ? 76  ASP C CA  1 
ATOM   4101 C C   . ASP C 1 77  ? 67.16922 49.62524 80.58714  1.000 31.18621 ? 76  ASP C C   1 
ATOM   4102 O O   . ASP C 1 77  ? 67.88480 50.18799 81.43117  1.000 33.10960 ? 76  ASP C O   1 
ATOM   4103 C CB  . ASP C 1 77  ? 65.44100 48.09616 81.49995  1.000 30.82463 ? 76  ASP C CB  1 
ATOM   4104 C CG  . ASP C 1 77  ? 64.15550 48.00503 82.25490  1.000 35.29818 ? 76  ASP C CG  1 
ATOM   4105 O OD1 . ASP C 1 77  ? 63.30216 48.90653 82.10818  1.000 33.13693 ? 76  ASP C OD1 1 
ATOM   4106 O OD2 . ASP C 1 77  ? 64.03747 47.02343 83.01794  1.000 37.98366 ? 76  ASP C OD2 1 
ATOM   4107 N N   . SER C 1 78  ? 67.65350 49.21497 79.39050  1.000 30.99551 ? 77  SER C N   1 
ATOM   4108 C CA  . SER C 1 78  ? 69.09147 49.28605 79.07886  1.000 35.33510 ? 77  SER C CA  1 
ATOM   4109 C C   . SER C 1 78  ? 69.58046 50.73329 78.94997  1.000 35.98737 ? 77  SER C C   1 
ATOM   4110 O O   . SER C 1 78  ? 70.77432 51.00206 79.12955  1.000 43.37708 ? 77  SER C O   1 
ATOM   4111 C CB  . SER C 1 78  ? 69.39361 48.48850 77.80237  1.000 34.14534 ? 77  SER C CB  1 
ATOM   4112 O OG  . SER C 1 78  ? 68.67343 49.07645 76.72829  1.000 38.15260 ? 77  SER C OG  1 
ATOM   4113 N N   . ASN C 1 79  ? 68.67722 51.69069 78.73891  1.000 34.00259 ? 78  ASN C N   1 
ATOM   4114 C CA  . ASN C 1 79  ? 69.10930 53.07720 78.61719  1.000 31.41374 ? 78  ASN C CA  1 
ATOM   4115 C C   . ASN C 1 79  ? 68.48247 53.99428 79.65540  1.000 31.00844 ? 78  ASN C C   1 
ATOM   4116 O O   . ASN C 1 79  ? 68.49828 55.21180 79.47671  1.000 35.61380 ? 78  ASN C O   1 
ATOM   4117 C CB  . ASN C 1 79  ? 68.79294 53.63486 77.23240  1.000 32.20556 ? 78  ASN C CB  1 
ATOM   4118 C CG  . ASN C 1 79  ? 69.41667 52.84836 76.10191  1.000 33.45886 ? 78  ASN C CG  1 
ATOM   4119 O OD1 . ASN C 1 79  ? 68.88532 51.82271 75.68591  1.000 32.97973 ? 78  ASN C OD1 1 
ATOM   4120 N ND2 . ASN C 1 79  ? 70.49400 53.37440 75.53959  1.000 25.24879 ? 78  ASN C ND2 1 
ATOM   4121 N N   . SER C 1 80  ? 67.89536 53.43622 80.70479  1.000 33.08571 ? 79  SER C N   1 
ATOM   4122 C CA  . SER C 1 80  ? 67.36397 54.21002 81.81232  1.000 25.56091 ? 79  SER C CA  1 
ATOM   4123 C C   . SER C 1 80  ? 66.41717 55.28644 81.29960  1.000 28.73758 ? 79  SER C C   1 
ATOM   4124 O O   . SER C 1 80  ? 66.56570 56.47170 81.60473  1.000 30.01757 ? 79  SER C O   1 
ATOM   4125 C CB  . SER C 1 80  ? 68.48419 54.83601 82.64535  1.000 23.89623 ? 79  SER C CB  1 
ATOM   4126 O OG  . SER C 1 80  ? 69.06168 53.91925 83.54462  1.000 26.03190 ? 79  SER C OG  1 
ATOM   4127 N N   . ILE C 1 81  ? 65.44092 54.88123 80.49327  1.000 28.81155 ? 80  ILE C N   1 
ATOM   4128 C CA  . ILE C 1 81  ? 64.60695 55.89525 79.86486  1.000 26.48751 ? 80  ILE C CA  1 
ATOM   4129 C C   . ILE C 1 81  ? 63.18570 55.37780 79.66851  1.000 24.24524 ? 80  ILE C C   1 
ATOM   4130 O O   . ILE C 1 81  ? 62.98131 54.30153 79.09940  1.000 25.06480 ? 80  ILE C O   1 
ATOM   4131 C CB  . ILE C 1 81  ? 65.27301 56.37351 78.55675  1.000 29.50998 ? 80  ILE C CB  1 
ATOM   4132 C CG1 . ILE C 1 81  ? 64.69772 57.70883 78.09262  1.000 25.58660 ? 80  ILE C CG1 1 
ATOM   4133 C CG2 . ILE C 1 81  ? 65.23945 55.31026 77.46768  1.000 29.45432 ? 80  ILE C CG2 1 
ATOM   4134 C CD1 . ILE C 1 81  ? 65.48963 58.31111 77.00102  1.000 26.02851 ? 80  ILE C CD1 1 
ATOM   4135 N N   . ALA C 1 82  ? 62.21240 56.08745 80.24098  1.000 19.53246 ? 81  ALA C N   1 
ATOM   4136 C CA  . ALA C 1 82  ? 60.78662 55.86848 80.03955  1.000 17.99030 ? 81  ALA C CA  1 
ATOM   4137 C C   . ALA C 1 82  ? 60.25218 56.93779 79.09625  1.000 25.05777 ? 81  ALA C C   1 
ATOM   4138 O O   . ALA C 1 82  ? 60.84433 58.01176 78.95071  1.000 27.00002 ? 81  ALA C O   1 
ATOM   4139 C CB  . ALA C 1 82  ? 60.02142 55.91534 81.36123  1.000 14.54197 ? 81  ALA C CB  1 
ATOM   4140 N N   . TYR C 1 83  ? 59.12378 56.63577 78.44788  1.000 25.61362 ? 82  TYR C N   1 
ATOM   4141 C CA  . TYR C 1 83  ? 58.56599 57.50906 77.42407  1.000 24.85014 ? 82  TYR C CA  1 
ATOM   4142 C C   . TYR C 1 83  ? 57.06917 57.71105 77.63964  1.000 25.85078 ? 82  TYR C C   1 
ATOM   4143 O O   . TYR C 1 83  ? 56.37262 56.84522 78.17812  1.000 21.74971 ? 82  TYR C O   1 
ATOM   4144 C CB  . TYR C 1 83  ? 58.77972 56.96588 75.98953  1.000 22.77638 ? 82  TYR C CB  1 
ATOM   4145 C CG  . TYR C 1 83  ? 60.21366 56.69343 75.57729  1.000 27.96114 ? 82  TYR C CG  1 
ATOM   4146 C CD1 . TYR C 1 83  ? 61.00962 57.67416 74.98027  1.000 26.05561 ? 82  TYR C CD1 1 
ATOM   4147 C CD2 . TYR C 1 83  ? 60.76254 55.42704 75.74964  1.000 29.74084 ? 82  TYR C CD2 1 
ATOM   4148 C CE1 . TYR C 1 83  ? 62.32765 57.39360 74.59202  1.000 24.85653 ? 82  TYR C CE1 1 
ATOM   4149 C CE2 . TYR C 1 83  ? 62.06804 55.13959 75.36620  1.000 24.66443 ? 82  TYR C CE2 1 
ATOM   4150 C CZ  . TYR C 1 83  ? 62.84341 56.11121 74.78754  1.000 26.71325 ? 82  TYR C CZ  1 
ATOM   4151 O OH  . TYR C 1 83  ? 64.12908 55.76010 74.43819  1.000 22.26535 ? 82  TYR C OH  1 
ATOM   4152 N N   . LEU C 1 84  ? 56.58496 58.88015 77.21677  1.000 24.87166 ? 83  LEU C N   1 
ATOM   4153 C CA  . LEU C 1 84  ? 55.16174 59.12484 77.05732  1.000 23.18262 ? 83  LEU C CA  1 
ATOM   4154 C C   . LEU C 1 84  ? 54.94179 59.55724 75.61978  1.000 26.86824 ? 83  LEU C C   1 
ATOM   4155 O O   . LEU C 1 84  ? 55.52034 60.55023 75.17179  1.000 25.81401 ? 83  LEU C O   1 
ATOM   4156 C CB  . LEU C 1 84  ? 54.63980 60.18235 78.02843  1.000 25.04490 ? 83  LEU C CB  1 
ATOM   4157 C CG  . LEU C 1 84  ? 53.20710 60.69376 77.76758  1.000 27.81204 ? 83  LEU C CG  1 
ATOM   4158 C CD1 . LEU C 1 84  ? 52.12549 59.64705 78.04907  1.000 22.44557 ? 83  LEU C CD1 1 
ATOM   4159 C CD2 . LEU C 1 84  ? 52.94716 61.97743 78.56704  1.000 24.89431 ? 83  LEU C CD2 1 
ATOM   4160 N N   . GLN C 1 85  ? 54.15858 58.76972 74.89121  1.000 27.87217 ? 84  GLN C N   1 
ATOM   4161 C CA  . GLN C 1 85  ? 53.75033 59.07171 73.53039  1.000 25.19112 ? 84  GLN C CA  1 
ATOM   4162 C C   . GLN C 1 85  ? 52.32388 59.59005 73.58360  1.000 30.68194 ? 84  GLN C C   1 
ATOM   4163 O O   . GLN C 1 85  ? 51.41987 58.87925 74.04311  1.000 28.27914 ? 84  GLN C O   1 
ATOM   4164 C CB  . GLN C 1 85  ? 53.80742 57.82941 72.65572  1.000 24.49697 ? 84  GLN C CB  1 
ATOM   4165 C CG  . GLN C 1 85  ? 53.19812 58.02964 71.31073  1.000 26.66508 ? 84  GLN C CG  1 
ATOM   4166 C CD  . GLN C 1 85  ? 54.23145 58.27113 70.26386  1.000 32.99605 ? 84  GLN C CD  1 
ATOM   4167 O OE1 . GLN C 1 85  ? 55.10495 57.41993 70.04256  1.000 34.09656 ? 84  GLN C OE1 1 
ATOM   4168 N NE2 . GLN C 1 85  ? 54.17345 59.43954 69.62130  1.000 29.69045 ? 84  GLN C NE2 1 
ATOM   4169 N N   . MET C 1 86  ? 52.11398 60.79337 73.06182  1.000 30.08491 ? 85  MET C N   1 
ATOM   4170 C CA  . MET C 1 86  ? 50.80951 61.44018 73.06315  1.000 30.38385 ? 85  MET C CA  1 
ATOM   4171 C C   . MET C 1 86  ? 50.34506 61.52279 71.62485  1.000 27.93677 ? 85  MET C C   1 
ATOM   4172 O O   . MET C 1 86  ? 51.12337 61.89496 70.74653  1.000 30.39538 ? 85  MET C O   1 
ATOM   4173 C CB  . MET C 1 86  ? 50.89217 62.83435 73.67777  1.000 35.36507 ? 85  MET C CB  1 
ATOM   4174 C CG  . MET C 1 86  ? 51.56771 62.86206 75.03159  1.000 33.76498 ? 85  MET C CG  1 
ATOM   4175 S SD  . MET C 1 86  ? 51.38756 64.43488 75.88083  1.000 33.74526 ? 85  MET C SD  1 
ATOM   4176 C CE  . MET C 1 86  ? 52.99747 65.09450 75.49982  1.000 26.78599 ? 85  MET C CE  1 
ATOM   4177 N N   . ASN C 1 87  ? 49.10810 61.11785 71.37969  1.000 29.79798 ? 86  ASN C N   1 
ATOM   4178 C CA  . ASN C 1 87  ? 48.52775 61.11696 70.04574  1.000 26.85932 ? 86  ASN C CA  1 
ATOM   4179 C C   . ASN C 1 87  ? 47.23612 61.91567 70.06718  1.000 28.34314 ? 86  ASN C C   1 
ATOM   4180 O O   . ASN C 1 87  ? 46.55448 61.98185 71.09141  1.000 38.46586 ? 86  ASN C O   1 
ATOM   4181 C CB  . ASN C 1 87  ? 48.24143 59.67702 69.55453  1.000 31.19536 ? 86  ASN C CB  1 
ATOM   4182 C CG  . ASN C 1 87  ? 49.42508 58.74534 69.73804  1.000 28.21537 ? 86  ASN C CG  1 
ATOM   4183 O OD1 . ASN C 1 87  ? 50.53845 59.04959 69.30432  1.000 31.82727 ? 86  ASN C OD1 1 
ATOM   4184 N ND2 . ASN C 1 87  ? 49.19640 57.60962 70.39695  1.000 29.55712 ? 86  ASN C ND2 1 
ATOM   4185 N N   . SER C 1 88  ? 46.89876 62.51277 68.93064  1.000 27.93335 ? 87  SER C N   1 
ATOM   4186 C CA  . SER C 1 88  ? 45.69479 63.33176 68.78479  1.000 32.96622 ? 87  SER C CA  1 
ATOM   4187 C C   . SER C 1 88  ? 45.58139 64.38851 69.89208  1.000 31.23643 ? 87  SER C C   1 
ATOM   4188 O O   . SER C 1 88  ? 44.57336 64.49943 70.59654  1.000 26.52670 ? 87  SER C O   1 
ATOM   4189 C CB  . SER C 1 88  ? 44.45638 62.43380 68.73354  1.000 29.72012 ? 87  SER C CB  1 
ATOM   4190 O OG  . SER C 1 88  ? 44.42258 61.72833 67.50402  1.000 28.03767 ? 87  SER C OG  1 
ATOM   4191 N N   . LEU C 1 89  ? 46.63534 65.19780 69.99944  1.000 30.27918 ? 88  LEU C N   1 
ATOM   4192 C CA  . LEU C 1 89  ? 46.70365 66.24596 71.01615  1.000 36.81508 ? 88  LEU C CA  1 
ATOM   4193 C C   . LEU C 1 89  ? 45.64996 67.32216 70.78682  1.000 34.70260 ? 88  LEU C C   1 
ATOM   4194 O O   . LEU C 1 89  ? 45.47900 67.81758 69.66739  1.000 33.00544 ? 88  LEU C O   1 
ATOM   4195 C CB  . LEU C 1 89  ? 48.08599 66.89351 71.03050  1.000 32.19679 ? 88  LEU C CB  1 
ATOM   4196 C CG  . LEU C 1 89  ? 49.19696 65.99855 71.53175  1.000 31.79619 ? 88  LEU C CG  1 
ATOM   4197 C CD1 . LEU C 1 89  ? 50.56103 66.63658 71.29794  1.000 31.53421 ? 88  LEU C CD1 1 
ATOM   4198 C CD2 . LEU C 1 89  ? 48.93424 65.85026 72.99033  1.000 28.02560 ? 88  LEU C CD2 1 
ATOM   4199 N N   . THR C 1 90  ? 44.90559 67.63855 71.83394  1.000 29.27072 ? 89  THR C N   1 
ATOM   4200 C CA  . THR C 1 90  ? 43.98243 68.76033 71.82377  1.000 34.11602 ? 89  THR C CA  1 
ATOM   4201 C C   . THR C 1 90  ? 44.57671 69.90088 72.64560  1.000 32.80865 ? 89  THR C C   1 
ATOM   4202 O O   . THR C 1 90  ? 45.63969 69.76209 73.25348  1.000 31.59482 ? 89  THR C O   1 
ATOM   4203 C CB  . THR C 1 90  ? 42.61968 68.33539 72.36656  1.000 33.67837 ? 89  THR C CB  1 
ATOM   4204 O OG1 . THR C 1 90  ? 42.65264 68.35024 73.79693  1.000 41.65978 ? 89  THR C OG1 1 
ATOM   4205 C CG2 . THR C 1 90  ? 42.31485 66.92869 71.90747  1.000 31.78498 ? 89  THR C CG2 1 
ATOM   4206 N N   . THR C 1 91  ? 43.91845 71.06191 72.61935  1.000 26.35572 ? 90  THR C N   1 
ATOM   4207 C CA  . THR C 1 91  ? 44.40543 72.15365 73.45544  1.000 31.34158 ? 90  THR C CA  1 
ATOM   4208 C C   . THR C 1 91  ? 44.31592 71.81455 74.93443  1.000 29.89028 ? 90  THR C C   1 
ATOM   4209 O O   . THR C 1 91  ? 45.08484 72.35949 75.72735  1.000 31.79200 ? 90  THR C O   1 
ATOM   4210 C CB  . THR C 1 91  ? 43.64542 73.47355 73.20261  1.000 43.57520 ? 90  THR C CB  1 
ATOM   4211 O OG1 . THR C 1 91  ? 42.29671 73.38436 73.69254  1.000 49.55254 ? 90  THR C OG1 1 
ATOM   4212 C CG2 . THR C 1 91  ? 43.63384 73.86083 71.71894  1.000 39.13334 ? 90  THR C CG2 1 
ATOM   4213 N N   . GLU C 1 92  ? 43.42898 70.90083 75.32106  1.000 34.24854 ? 91  GLU C N   1 
ATOM   4214 C CA  . GLU C 1 92  ? 43.32972 70.47894 76.71628  1.000 32.39318 ? 91  GLU C CA  1 
ATOM   4215 C C   . GLU C 1 92  ? 44.51553 69.67456 77.18278  1.000 29.66965 ? 91  GLU C C   1 
ATOM   4216 O O   . GLU C 1 92  ? 44.51822 69.22374 78.32689  1.000 33.90923 ? 91  GLU C O   1 
ATOM   4217 C CB  . GLU C 1 92  ? 42.09350 69.61366 76.94003  1.000 37.63067 ? 91  GLU C CB  1 
ATOM   4218 C CG  . GLU C 1 92  ? 40.87819 70.31283 77.47490  1.000 42.47463 ? 91  GLU C CG  1 
ATOM   4219 C CD  . GLU C 1 92  ? 39.68058 69.38522 77.51914  1.000 58.25617 ? 91  GLU C CD  1 
ATOM   4220 O OE1 . GLU C 1 92  ? 39.74499 68.30274 76.88064  1.000 53.29853 ? 91  GLU C OE1 1 
ATOM   4221 O OE2 . GLU C 1 92  ? 38.69887 69.71865 78.22485  1.000 71.59981 ? 91  GLU C OE2 1 
ATOM   4222 N N   . ASP C 1 93  ? 45.51267 69.48704 76.33844  1.000 34.40931 ? 92  ASP C N   1 
ATOM   4223 C CA  . ASP C 1 93  ? 46.73008 68.78949 76.70190  1.000 31.92869 ? 92  ASP C CA  1 
ATOM   4224 C C   . ASP C 1 93  ? 47.86069 69.74553 77.03788  1.000 29.97629 ? 92  ASP C C   1 
ATOM   4225 O O   . ASP C 1 93  ? 48.97081 69.29506 77.32636  1.000 32.32255 ? 92  ASP C O   1 
ATOM   4226 C CB  . ASP C 1 93  ? 47.16477 67.86123 75.55364  1.000 32.22546 ? 92  ASP C CB  1 
ATOM   4227 C CG  . ASP C 1 93  ? 46.12514 66.80122 75.22402  1.000 33.28592 ? 92  ASP C CG  1 
ATOM   4228 O OD1 . ASP C 1 93  ? 45.72238 66.71026 74.03306  1.000 30.31796 ? 92  ASP C OD1 1 
ATOM   4229 O OD2 . ASP C 1 93  ? 45.73348 66.05390 76.15834  1.000 35.44960 ? 92  ASP C OD2 1 
ATOM   4230 N N   . THR C 1 94  ? 47.63532 71.04659 76.94473  1.000 26.87143 ? 93  THR C N   1 
ATOM   4231 C CA  . THR C 1 94  ? 48.68422 71.97867 77.31800  1.000 30.29800 ? 93  THR C CA  1 
ATOM   4232 C C   . THR C 1 94  ? 48.92956 71.87666 78.81630  1.000 30.08251 ? 93  THR C C   1 
ATOM   4233 O O   . THR C 1 94  ? 48.00423 72.03513 79.61826  1.000 27.68068 ? 93  THR C O   1 
ATOM   4234 C CB  . THR C 1 94  ? 48.33175 73.40375 76.91977  1.000 30.70189 ? 93  THR C CB  1 
ATOM   4235 O OG1 . THR C 1 94  ? 48.12241 73.45817 75.50328  1.000 37.46850 ? 93  THR C OG1 1 
ATOM   4236 C CG2 . THR C 1 94  ? 49.49021 74.32579 77.26776  1.000 27.60955 ? 93  THR C CG2 1 
ATOM   4237 N N   . ALA C 1 95  ? 50.17104 71.59383 79.18039  1.000 23.11116 ? 94  ALA C N   1 
ATOM   4238 C CA  . ALA C 1 95  ? 50.57432 71.45186 80.56398  1.000 25.64195 ? 94  ALA C CA  1 
ATOM   4239 C C   . ALA C 1 95  ? 52.08276 71.33856 80.56127  1.000 29.05667 ? 94  ALA C C   1 
ATOM   4240 O O   . ALA C 1 95  ? 52.70989 71.20073 79.50587  1.000 23.50744 ? 94  ALA C O   1 
ATOM   4241 C CB  . ALA C 1 95  ? 49.95328 70.22071 81.21487  1.000 24.67963 ? 94  ALA C CB  1 
ATOM   4242 N N   . ILE C 1 96  ? 52.66271 71.41193 81.74910  1.000 27.12804 ? 95  ILE C N   1 
ATOM   4243 C CA  . ILE C 1 96  ? 54.02172 70.93602 81.93569  1.000 27.20280 ? 95  ILE C CA  1 
ATOM   4244 C C   . ILE C 1 96  ? 53.91760 69.46711 82.28980  1.000 25.66588 ? 95  ILE C C   1 
ATOM   4245 O O   . ILE C 1 96  ? 53.12561 69.08289 83.16126  1.000 23.20502 ? 95  ILE C O   1 
ATOM   4246 C CB  . ILE C 1 96  ? 54.77059 71.71426 83.02625  1.000 27.13671 ? 95  ILE C CB  1 
ATOM   4247 C CG1 . ILE C 1 96  ? 55.13691 73.11133 82.55338  1.000 26.73581 ? 95  ILE C CG1 1 
ATOM   4248 C CG2 . ILE C 1 96  ? 56.06286 71.00351 83.37709  1.000 21.51085 ? 95  ILE C CG2 1 
ATOM   4249 C CD1 . ILE C 1 96  ? 55.85562 73.90220 83.63429  1.000 27.70162 ? 95  ILE C CD1 1 
ATOM   4250 N N   . TYR C 1 97  ? 54.71691 68.65015 81.61927  1.000 23.80675 ? 96  TYR C N   1 
ATOM   4251 C CA  . TYR C 1 97  ? 54.65778 67.20561 81.74972  1.000 23.64469 ? 96  TYR C CA  1 
ATOM   4252 C C   . TYR C 1 97  ? 55.83406 66.76232 82.59957  1.000 24.85124 ? 96  TYR C C   1 
ATOM   4253 O O   . TYR C 1 97  ? 56.97805 67.13305 82.32117  1.000 30.39935 ? 96  TYR C O   1 
ATOM   4254 C CB  . TYR C 1 97  ? 54.66149 66.54582 80.37355  1.000 21.51718 ? 96  TYR C CB  1 
ATOM   4255 C CG  . TYR C 1 97  ? 53.28384 66.55664 79.82281  1.000 22.97017 ? 96  TYR C CG  1 
ATOM   4256 C CD1 . TYR C 1 97  ? 52.82121 67.61855 79.05662  1.000 25.54581 ? 96  TYR C CD1 1 
ATOM   4257 C CD2 . TYR C 1 97  ? 52.40582 65.55811 80.15439  1.000 23.71663 ? 96  TYR C CD2 1 
ATOM   4258 C CE1 . TYR C 1 97  ? 51.52425 67.64764 78.60054  1.000 20.81965 ? 96  TYR C CE1 1 
ATOM   4259 C CE2 . TYR C 1 97  ? 51.12412 65.57595 79.71198  1.000 27.51399 ? 96  TYR C CE2 1 
ATOM   4260 C CZ  . TYR C 1 97  ? 50.67835 66.61675 78.93866  1.000 26.91638 ? 96  TYR C CZ  1 
ATOM   4261 O OH  . TYR C 1 97  ? 49.37231 66.58645 78.50684  1.000 33.31326 ? 96  TYR C OH  1 
ATOM   4262 N N   . TYR C 1 98  ? 55.53887 66.05784 83.68779  1.000 26.40175 ? 97  TYR C N   1 
ATOM   4263 C CA  . TYR C 1 98  ? 56.54519 65.65275 84.65958  1.000 29.04186 ? 97  TYR C CA  1 
ATOM   4264 C C   . TYR C 1 98  ? 56.65825 64.13644 84.68400  1.000 26.45240 ? 97  TYR C C   1 
ATOM   4265 O O   . TYR C 1 98  ? 55.64565 63.42759 84.59776  1.000 19.21362 ? 97  TYR C O   1 
ATOM   4266 C CB  . TYR C 1 98  ? 56.21686 66.17145 86.08328  1.000 25.77247 ? 97  TYR C CB  1 
ATOM   4267 C CG  . TYR C 1 98  ? 56.16219 67.67753 86.26355  1.000 27.36925 ? 97  TYR C CG  1 
ATOM   4268 C CD1 . TYR C 1 98  ? 57.33785 68.42923 86.37298  1.000 36.68162 ? 97  TYR C CD1 1 
ATOM   4269 C CD2 . TYR C 1 98  ? 54.94220 68.35764 86.36236  1.000 28.78467 ? 97  TYR C CD2 1 
ATOM   4270 C CE1 . TYR C 1 98  ? 57.30321 69.82027 86.55987  1.000 27.86442 ? 97  TYR C CE1 1 
ATOM   4271 C CE2 . TYR C 1 98  ? 54.90045 69.75392 86.55631  1.000 25.61189 ? 97  TYR C CE2 1 
ATOM   4272 C CZ  . TYR C 1 98  ? 56.08957 70.46826 86.65637  1.000 25.20337 ? 97  TYR C CZ  1 
ATOM   4273 O OH  . TYR C 1 98  ? 56.08365 71.83738 86.84199  1.000 30.90777 ? 97  TYR C OH  1 
ATOM   4274 N N   . CYS C 1 99  ? 57.89696 63.65684 84.80514  1.000 25.86262 ? 98  CYS C N   1 
ATOM   4275 C CA  . CYS C 1 99  ? 58.20762 62.24559 84.95563  1.000 23.18253 ? 98  CYS C CA  1 
ATOM   4276 C C   . CYS C 1 99  ? 58.70104 61.98399 86.36906  1.000 26.28329 ? 98  CYS C C   1 
ATOM   4277 O O   . CYS C 1 99  ? 59.58283 62.69740 86.85108  1.000 30.41736 ? 98  CYS C O   1 
ATOM   4278 C CB  . CYS C 1 99  ? 59.27708 61.85800 83.95002  1.000 31.86555 ? 98  CYS C CB  1 
ATOM   4279 S SG  . CYS C 1 99  ? 59.94450 60.22394 84.13910  1.000 44.89815 ? 98  CYS C SG  1 
ATOM   4280 N N   . ALA C 1 100 ? 58.23167 60.90181 86.99959  1.000 25.05005 ? 99  ALA C N   1 
ATOM   4281 C CA  . ALA C 1 100 ? 58.52131 60.69625 88.41796  1.000 26.55424 ? 99  ALA C CA  1 
ATOM   4282 C C   . ALA C 1 100 ? 58.75522 59.22610 88.73844  1.000 27.43886 ? 99  ALA C C   1 
ATOM   4283 O O   . ALA C 1 100 ? 58.05044 58.34556 88.23798  1.000 29.33841 ? 99  ALA C O   1 
ATOM   4284 C CB  . ALA C 1 100 ? 57.38268 61.23073 89.31250  1.000 23.02677 ? 99  ALA C CB  1 
ATOM   4285 N N   . ARG C 1 101 ? 59.67666 58.99001 89.67731  1.000 22.19096 ? 100 ARG C N   1 
ATOM   4286 C CA  . ARG C 1 101 ? 60.05415 57.65418 90.12569  1.000 26.58880 ? 100 ARG C CA  1 
ATOM   4287 C C   . ARG C 1 101 ? 59.29673 57.23293 91.38276  1.000 28.42436 ? 100 ARG C C   1 
ATOM   4288 O O   . ARG C 1 101 ? 59.10075 58.03792 92.29466  1.000 32.84775 ? 100 ARG C O   1 
ATOM   4289 C CB  . ARG C 1 101 ? 61.55433 57.61469 90.41188  1.000 26.20870 ? 100 ARG C CB  1 
ATOM   4290 C CG  . ARG C 1 101 ? 62.14169 56.22120 90.68024  1.000 28.10131 ? 100 ARG C CG  1 
ATOM   4291 C CD  . ARG C 1 101 ? 63.47790 56.36196 91.42832  1.000 26.23956 ? 100 ARG C CD  1 
ATOM   4292 N NE  . ARG C 1 101 ? 63.30095 56.22841 92.87114  1.000 27.24403 ? 100 ARG C NE  1 
ATOM   4293 C CZ  . ARG C 1 101 ? 64.24471 55.82209 93.71491  1.000 27.47691 ? 100 ARG C CZ  1 
ATOM   4294 N NH1 . ARG C 1 101 ? 65.46361 55.53156 93.27324  1.000 27.69199 ? 100 ARG C NH1 1 
ATOM   4295 N NH2 . ARG C 1 101 ? 63.97574 55.73248 95.01048  1.000 23.60888 ? 100 ARG C NH2 1 
ATOM   4296 N N   . ASP C 1 102 ? 58.86278 55.96660 91.41560  1.000 26.22636 ? 101 ASP C N   1 
ATOM   4297 C CA  . ASP C 1 102 ? 58.34411 55.35335 92.64006  1.000 24.34565 ? 101 ASP C CA  1 
ATOM   4298 C C   . ASP C 1 102 ? 59.29357 55.59862 93.80238  1.000 25.92256 ? 101 ASP C C   1 
ATOM   4299 O O   . ASP C 1 102 ? 60.51554 55.52378 93.64424  1.000 28.33118 ? 101 ASP C O   1 
ATOM   4300 C CB  . ASP C 1 102 ? 58.16094 53.83984 92.44947  1.000 29.08334 ? 101 ASP C CB  1 
ATOM   4301 C CG  . ASP C 1 102 ? 57.21544 53.19512 93.48730  1.000 28.18706 ? 101 ASP C CG  1 
ATOM   4302 O OD1 . ASP C 1 102 ? 56.69685 52.08277 93.22640  1.000 23.20040 ? 101 ASP C OD1 1 
ATOM   4303 O OD2 . ASP C 1 102 ? 56.99000 53.78517 94.56014  1.000 32.40328 ? 101 ASP C OD2 1 
ATOM   4304 N N   . PHE C 1 103 ? 58.72545 55.95409 94.96769  1.000 26.87446 ? 102 PHE C N   1 
ATOM   4305 C CA  . PHE C 1 103 ? 59.54667 56.06998 96.17166  1.000 23.56602 ? 102 PHE C CA  1 
ATOM   4306 C C   . PHE C 1 103 ? 60.26923 54.76807 96.48948  1.000 22.30379 ? 102 PHE C C   1 
ATOM   4307 O O   . PHE C 1 103 ? 61.41847 54.80458 96.92059  1.000 20.23422 ? 102 PHE C O   1 
ATOM   4308 C CB  . PHE C 1 103 ? 58.71100 56.53277 97.36943  1.000 22.79854 ? 102 PHE C CB  1 
ATOM   4309 C CG  . PHE C 1 103 ? 59.55118 57.02816 98.53867  1.000 28.45650 ? 102 PHE C CG  1 
ATOM   4310 C CD1 . PHE C 1 103 ? 59.84859 56.19508 99.61763  1.000 34.38668 ? 102 PHE C CD1 1 
ATOM   4311 C CD2 . PHE C 1 103 ? 60.07557 58.31660 98.54542  1.000 25.00106 ? 102 PHE C CD2 1 
ATOM   4312 C CE1 . PHE C 1 103 ? 60.63376 56.64488 100.69853 1.000 25.22721 ? 102 PHE C CE1 1 
ATOM   4313 C CE2 . PHE C 1 103 ? 60.86183 58.75821 99.61052  1.000 31.19109 ? 102 PHE C CE2 1 
ATOM   4314 C CZ  . PHE C 1 103 ? 61.13669 57.91808 100.68945 1.000 23.51776 ? 102 PHE C CZ  1 
ATOM   4315 N N   . TYR C 1 104 ? 59.65072 53.61787 96.22450  1.000 25.74789 ? 103 TYR C N   1 
ATOM   4316 C CA  . TYR C 1 104 ? 60.25244 52.32170 96.51435  1.000 30.37104 ? 103 TYR C CA  1 
ATOM   4317 C C   . TYR C 1 104 ? 60.49629 51.52095 95.23762  1.000 29.12392 ? 103 TYR C C   1 
ATOM   4318 O O   . TYR C 1 104 ? 60.02918 51.87707 94.15466  1.000 30.09201 ? 103 TYR C O   1 
ATOM   4319 C CB  . TYR C 1 104 ? 59.36477 51.49408 97.44305  1.000 28.78495 ? 103 TYR C CB  1 
ATOM   4320 C CG  . TYR C 1 104 ? 58.98448 52.18128 98.71578  1.000 29.68359 ? 103 TYR C CG  1 
ATOM   4321 C CD1 . TYR C 1 104 ? 59.86063 52.19988 99.80027  1.000 28.18812 ? 103 TYR C CD1 1 
ATOM   4322 C CD2 . TYR C 1 104 ? 57.74578 52.78941 98.84925  1.000 24.28523 ? 103 TYR C CD2 1 
ATOM   4323 C CE1 . TYR C 1 104 ? 59.52240 52.81301 100.98087 1.000 24.87014 ? 103 TYR C CE1 1 
ATOM   4324 C CE2 . TYR C 1 104 ? 57.39583 53.40042 100.02694 1.000 31.21121 ? 103 TYR C CE2 1 
ATOM   4325 C CZ  . TYR C 1 104 ? 58.28452 53.41054 101.09699 1.000 30.60500 ? 103 TYR C CZ  1 
ATOM   4326 O OH  . TYR C 1 104 ? 57.93428 54.03368 102.27967 1.000 30.25915 ? 103 TYR C OH  1 
ATOM   4327 N N   . ASP C 1 105 ? 61.25114 50.42546 95.38562  1.000 27.38279 ? 104 ASP C N   1 
ATOM   4328 C CA  . ASP C 1 105 ? 61.41906 49.41014 94.34979  1.000 24.69353 ? 104 ASP C CA  1 
ATOM   4329 C C   . ASP C 1 105 ? 60.29211 48.37975 94.41166  1.000 27.01830 ? 104 ASP C C   1 
ATOM   4330 O O   . ASP C 1 105 ? 59.44102 48.40286 95.30777  1.000 26.03627 ? 104 ASP C O   1 
ATOM   4331 C CB  . ASP C 1 105 ? 62.77492 48.71645 94.46773  1.000 23.56789 ? 104 ASP C CB  1 
ATOM   4332 C CG  . ASP C 1 105 ? 62.97222 48.04490 95.79869  1.000 25.15678 ? 104 ASP C CG  1 
ATOM   4333 O OD1 . ASP C 1 105 ? 61.96910 47.74150 96.46686  1.000 26.44736 ? 104 ASP C OD1 1 
ATOM   4334 O OD2 . ASP C 1 105 ? 64.13953 47.80483 96.17852  1.000 26.47314 ? 104 ASP C OD2 1 
ATOM   4335 N N   . PHE C 1 106 ? 60.28478 47.46166 93.43822  1.000 24.14311 ? 105 PHE C N   1 
ATOM   4336 C CA  . PHE C 1 106 ? 59.15451 46.54571 93.35156  1.000 25.14476 ? 105 PHE C CA  1 
ATOM   4337 C C   . PHE C 1 106 ? 59.04949 45.62868 94.56094  1.000 25.45214 ? 105 PHE C C   1 
ATOM   4338 O O   . PHE C 1 106 ? 57.94326 45.18439 94.89590  1.000 22.44059 ? 105 PHE C O   1 
ATOM   4339 C CB  . PHE C 1 106 ? 59.24003 45.71051 92.07369  1.000 27.52450 ? 105 PHE C CB  1 
ATOM   4340 C CG  . PHE C 1 106 ? 60.42478 44.80528 92.01342  1.000 26.78552 ? 105 PHE C CG  1 
ATOM   4341 C CD1 . PHE C 1 106 ? 60.38680 43.55433 92.59641  1.000 20.89249 ? 105 PHE C CD1 1 
ATOM   4342 C CD2 . PHE C 1 106 ? 61.57576 45.20418 91.34837  1.000 28.93755 ? 105 PHE C CD2 1 
ATOM   4343 C CE1 . PHE C 1 106 ? 61.47216 42.73693 92.54481  1.000 22.12887 ? 105 PHE C CE1 1 
ATOM   4344 C CE2 . PHE C 1 106 ? 62.66637 44.38418 91.28782  1.000 25.10009 ? 105 PHE C CE2 1 
ATOM   4345 C CZ  . PHE C 1 106 ? 62.61404 43.14620 91.89193  1.000 27.77869 ? 105 PHE C CZ  1 
ATOM   4346 N N   . TRP C 1 107 ? 60.15872 45.39662 95.26406  1.000 24.51043 ? 106 TRP C N   1 
ATOM   4347 C CA  . TRP C 1 107 ? 60.12205 44.47574 96.39098  1.000 23.73777 ? 106 TRP C CA  1 
ATOM   4348 C C   . TRP C 1 107 ? 59.11969 44.93461 97.44192  1.000 25.19142 ? 106 TRP C C   1 
ATOM   4349 O O   . TRP C 1 107 ? 58.48958 44.10654 98.10475  1.000 38.31711 ? 106 TRP C O   1 
ATOM   4350 C CB  . TRP C 1 107 ? 61.51512 44.30513 97.00711  1.000 23.75578 ? 106 TRP C CB  1 
ATOM   4351 C CG  . TRP C 1 107 ? 62.64494 43.79941 96.09791  1.000 24.23426 ? 106 TRP C CG  1 
ATOM   4352 C CD1 . TRP C 1 107 ? 63.73557 44.50920 95.68936  1.000 27.94199 ? 106 TRP C CD1 1 
ATOM   4353 C CD2 . TRP C 1 107 ? 62.81722 42.47997 95.55695  1.000 28.77827 ? 106 TRP C CD2 1 
ATOM   4354 N NE1 . TRP C 1 107 ? 64.55611 43.73682 94.90133  1.000 26.55222 ? 106 TRP C NE1 1 
ATOM   4355 C CE2 . TRP C 1 107 ? 64.01721 42.48457 94.81054  1.000 32.16696 ? 106 TRP C CE2 1 
ATOM   4356 C CE3 . TRP C 1 107 ? 62.06452 41.30402 95.60468  1.000 27.26939 ? 106 TRP C CE3 1 
ATOM   4357 C CZ2 . TRP C 1 107 ? 64.47858 41.36111 94.13735  1.000 29.77173 ? 106 TRP C CZ2 1 
ATOM   4358 C CZ3 . TRP C 1 107 ? 62.52312 40.19909 94.93336  1.000 22.37116 ? 106 TRP C CZ3 1 
ATOM   4359 C CH2 . TRP C 1 107 ? 63.71574 40.23246 94.21000  1.000 25.79962 ? 106 TRP C CH2 1 
ATOM   4360 N N   . ASN C 1 108 ? 58.98599 46.24456 97.64174  1.000 31.04731 ? 107 ASN C N   1 
ATOM   4361 C CA  . ASN C 1 108 ? 58.35983 46.77057 98.85494  1.000 28.53171 ? 107 ASN C CA  1 
ATOM   4362 C C   . ASN C 1 108 ? 56.83268 46.72428 98.79809  1.000 25.06368 ? 107 ASN C C   1 
ATOM   4363 O O   . ASN C 1 108 ? 56.21464 47.04750 97.78125  1.000 20.69946 ? 107 ASN C O   1 
ATOM   4364 C CB  . ASN C 1 108 ? 58.84020 48.19650 99.10974  1.000 20.50461 ? 107 ASN C CB  1 
ATOM   4365 C CG  . ASN C 1 108 ? 58.36371 48.74979 100.41772 1.000 21.44686 ? 107 ASN C CG  1 
ATOM   4366 O OD1 . ASN C 1 108 ? 57.16285 48.90879 100.64454 1.000 25.43047 ? 107 ASN C OD1 1 
ATOM   4367 N ND2 . ASN C 1 108 ? 59.30412 49.07594 101.28869 1.000 21.11457 ? 107 ASN C ND2 1 
ATOM   4368 N N   . GLU C 1 109 ? 56.23491 46.39014 99.94815  1.000 33.76390 ? 108 GLU C N   1 
ATOM   4369 C CA  . GLU C 1 109 ? 54.78306 46.28606 100.08607 1.000 32.91335 ? 108 GLU C CA  1 
ATOM   4370 C C   . GLU C 1 109 ? 54.07784 47.59771 99.75539  1.000 36.20252 ? 108 GLU C C   1 
ATOM   4371 O O   . GLU C 1 109 ? 52.91606 47.58159 99.33582  1.000 35.09100 ? 108 GLU C O   1 
ATOM   4372 C CB  . GLU C 1 109 ? 54.43394 45.83076 101.50844 1.000 28.66770 ? 108 GLU C CB  1 
ATOM   4373 N N   . PHE C 1 110 ? 54.71429 48.73330 100.03963 1.000 27.96592 ? 109 PHE C N   1 
ATOM   4374 C CA  . PHE C 1 110 ? 54.13606 50.04861 99.82264  1.000 30.02712 ? 109 PHE C CA  1 
ATOM   4375 C C   . PHE C 1 110 ? 54.50510 50.67748 98.46988  1.000 34.59327 ? 109 PHE C C   1 
ATOM   4376 O O   . PHE C 1 110 ? 54.27897 51.88193 98.28078  1.000 32.80578 ? 109 PHE C O   1 
ATOM   4377 C CB  . PHE C 1 110 ? 54.54181 50.95139 100.97985 1.000 36.36366 ? 109 PHE C CB  1 
ATOM   4378 C CG  . PHE C 1 110 ? 54.31432 50.31082 102.30277 1.000 41.94559 ? 109 PHE C CG  1 
ATOM   4379 C CD1 . PHE C 1 110 ? 53.02499 50.00459 102.70885 1.000 42.74903 ? 109 PHE C CD1 1 
ATOM   4380 C CD2 . PHE C 1 110 ? 55.38266 49.94879 103.11734 1.000 47.49552 ? 109 PHE C CD2 1 
ATOM   4381 C CE1 . PHE C 1 110 ? 52.79622 49.37565 103.92848 1.000 57.88166 ? 109 PHE C CE1 1 
ATOM   4382 C CE2 . PHE C 1 110 ? 55.16591 49.31062 104.33778 1.000 49.42191 ? 109 PHE C CE2 1 
ATOM   4383 C CZ  . PHE C 1 110 ? 53.86903 49.02683 104.74413 1.000 57.37696 ? 109 PHE C CZ  1 
ATOM   4384 N N   . SER C 1 111 ? 55.09638 49.91554 97.54491  1.000 29.80201 ? 110 SER C N   1 
ATOM   4385 C CA  . SER C 1 111 ? 55.42989 50.46404 96.24280  1.000 20.67204 ? 110 SER C CA  1 
ATOM   4386 C C   . SER C 1 111 ? 54.15589 50.83685 95.49359  1.000 23.42988 ? 110 SER C C   1 
ATOM   4387 O O   . SER C 1 111 ? 53.05508 50.43372 95.86138  1.000 29.67918 ? 110 SER C O   1 
ATOM   4388 C CB  . SER C 1 111 ? 56.26181 49.47011 95.44491  1.000 25.53601 ? 110 SER C CB  1 
ATOM   4389 O OG  . SER C 1 111 ? 55.52380 48.30881 95.11720  1.000 24.66738 ? 110 SER C OG  1 
ATOM   4390 N N   . HIS C 1 112 ? 54.32397 51.60276 94.40816  1.000 27.41532 ? 111 HIS C N   1 
ATOM   4391 C CA  . HIS C 1 112 ? 53.21306 52.10907 93.58094  1.000 26.35872 ? 111 HIS C CA  1 
ATOM   4392 C C   . HIS C 1 112 ? 52.27747 53.03721 94.36897  1.000 27.22248 ? 111 HIS C C   1 
ATOM   4393 O O   . HIS C 1 112 ? 51.08724 53.15207 94.06007  1.000 29.89320 ? 111 HIS C O   1 
ATOM   4394 C CB  . HIS C 1 112 ? 52.40754 50.96168 92.94696  1.000 30.20021 ? 111 HIS C CB  1 
ATOM   4395 C CG  . HIS C 1 112 ? 53.23572 49.99000 92.15541  1.000 29.64654 ? 111 HIS C CG  1 
ATOM   4396 N ND1 . HIS C 1 112 ? 52.81192 48.70734 91.87599  1.000 26.03608 ? 111 HIS C ND1 1 
ATOM   4397 C CD2 . HIS C 1 112 ? 54.46190 50.11291 91.59118  1.000 26.76190 ? 111 HIS C CD2 1 
ATOM   4398 C CE1 . HIS C 1 112 ? 53.74194 48.08451 91.17667  1.000 26.78672 ? 111 HIS C CE1 1 
ATOM   4399 N NE2 . HIS C 1 112 ? 54.75183 48.91491 90.98856  1.000 26.73992 ? 111 HIS C NE2 1 
ATOM   4400 N N   . ARG C 1 113 ? 52.80736 53.73507 95.37250  1.000 24.80853 ? 112 ARG C N   1 
ATOM   4401 C CA  . ARG C 1 113 ? 51.97764 54.54981 96.24435  1.000 24.38506 ? 112 ARG C CA  1 
ATOM   4402 C C   . ARG C 1 113 ? 52.49749 55.97140 96.38882  1.000 26.90834 ? 112 ARG C C   1 
ATOM   4403 O O   . ARG C 1 113 ? 51.70490 56.89435 96.59484  1.000 28.09121 ? 112 ARG C O   1 
ATOM   4404 C CB  . ARG C 1 113 ? 51.85530 53.89490 97.62012  1.000 29.04372 ? 112 ARG C CB  1 
ATOM   4405 C CG  . ARG C 1 113 ? 50.82559 52.78481 97.65095  1.000 31.00394 ? 112 ARG C CG  1 
ATOM   4406 C CD  . ARG C 1 113 ? 49.57077 53.14555 96.87439  1.000 34.00564 ? 112 ARG C CD  1 
ATOM   4407 N NE  . ARG C 1 113 ? 48.55230 52.09135 96.93405  1.000 37.50300 ? 112 ARG C NE  1 
ATOM   4408 C CZ  . ARG C 1 113 ? 48.41253 51.12528 96.02629  1.000 41.21748 ? 112 ARG C CZ  1 
ATOM   4409 N NH1 . ARG C 1 113 ? 47.45480 50.21742 96.16631  1.000 37.25944 ? 112 ARG C NH1 1 
ATOM   4410 N NH2 . ARG C 1 113 ? 49.21576 51.07712 94.96492  1.000 38.84772 ? 112 ARG C NH2 1 
ATOM   4411 N N   . THR C 1 114 ? 53.82241 56.15083 96.34994  1.000 29.62465 ? 113 THR C N   1 
ATOM   4412 C CA  . THR C 1 114 ? 54.46941 57.43767 96.60220  1.000 27.19004 ? 113 THR C CA  1 
ATOM   4413 C C   . THR C 1 114 ? 55.46530 57.75094 95.49801  1.000 27.10754 ? 113 THR C C   1 
ATOM   4414 O O   . THR C 1 114 ? 56.28594 56.90168 95.13988  1.000 25.01415 ? 113 THR C O   1 
ATOM   4415 C CB  . THR C 1 114 ? 55.20848 57.42204 97.94615  1.000 22.20049 ? 113 THR C CB  1 
ATOM   4416 O OG1 . THR C 1 114 ? 54.25423 57.28667 98.99761  1.000 29.32378 ? 113 THR C OG1 1 
ATOM   4417 C CG2 . THR C 1 114 ? 55.97357 58.68877 98.14538  1.000 24.99014 ? 113 THR C CG2 1 
ATOM   4418 N N   . PHE C 1 115 ? 55.45645 58.98872 95.00940  1.000 28.69798 ? 114 PHE C N   1 
ATOM   4419 C CA  . PHE C 1 115 ? 56.30570 59.34094 93.88082  1.000 25.28604 ? 114 PHE C CA  1 
ATOM   4420 C C   . PHE C 1 115 ? 57.19739 60.52425 94.19846  1.000 29.74782 ? 114 PHE C C   1 
ATOM   4421 O O   . PHE C 1 115 ? 56.76588 61.49619 94.82468  1.000 34.65820 ? 114 PHE C O   1 
ATOM   4422 C CB  . PHE C 1 115 ? 55.45514 59.61343 92.66532  1.000 27.01755 ? 114 PHE C CB  1 
ATOM   4423 C CG  . PHE C 1 115 ? 54.82728 58.37800 92.13512  1.000 25.58737 ? 114 PHE C CG  1 
ATOM   4424 C CD1 . PHE C 1 115 ? 53.49970 58.10280 92.38462  1.000 25.77937 ? 114 PHE C CD1 1 
ATOM   4425 C CD2 . PHE C 1 115 ? 55.59959 57.44370 91.45930  1.000 26.44002 ? 114 PHE C CD2 1 
ATOM   4426 C CE1 . PHE C 1 115 ? 52.94010 56.94126 91.91661  1.000 27.17814 ? 114 PHE C CE1 1 
ATOM   4427 C CE2 . PHE C 1 115 ? 55.05454 56.28968 90.98640  1.000 23.27871 ? 114 PHE C CE2 1 
ATOM   4428 C CZ  . PHE C 1 115 ? 53.71932 56.03313 91.21437  1.000 28.60316 ? 114 PHE C CZ  1 
ATOM   4429 N N   . ASP C 1 116 ? 58.43494 60.44387 93.71187  1.000 30.76603 ? 115 ASP C N   1 
ATOM   4430 C CA  . ASP C 1 116 ? 59.49133 61.36168 94.09018  1.000 30.16048 ? 115 ASP C CA  1 
ATOM   4431 C C   . ASP C 1 116 ? 60.38738 61.64661 92.88304  1.000 30.73319 ? 115 ASP C C   1 
ATOM   4432 O O   . ASP C 1 116 ? 60.17205 61.13722 91.77837  1.000 29.74478 ? 115 ASP C O   1 
ATOM   4433 C CB  . ASP C 1 116 ? 60.27015 60.75780 95.26357  1.000 31.57432 ? 115 ASP C CB  1 
ATOM   4434 C CG  . ASP C 1 116 ? 61.06052 61.77910 96.03132  1.000 31.31596 ? 115 ASP C CG  1 
ATOM   4435 O OD1 . ASP C 1 116 ? 61.28233 62.88269 95.48238  1.000 37.02613 ? 115 ASP C OD1 1 
ATOM   4436 O OD2 . ASP C 1 116 ? 61.45791 61.47444 97.18119  1.000 32.86893 ? 115 ASP C OD2 1 
ATOM   4437 N N   . PHE C 1 117 ? 61.41540 62.46486 93.11765  1.000 33.71092 ? 116 PHE C N   1 
ATOM   4438 C CA  . PHE C 1 117 ? 62.47523 62.75611 92.14907  1.000 27.61605 ? 116 PHE C CA  1 
ATOM   4439 C C   . PHE C 1 117 ? 61.91677 63.27367 90.83321  1.000 30.30605 ? 116 PHE C C   1 
ATOM   4440 O O   . PHE C 1 117 ? 62.55826 63.14262 89.78299  1.000 27.19169 ? 116 PHE C O   1 
ATOM   4441 C CB  . PHE C 1 117 ? 63.34849 61.52920 91.91894  1.000 27.23033 ? 116 PHE C CB  1 
ATOM   4442 C CG  . PHE C 1 117 ? 63.99017 61.03350 93.16075  1.000 29.98964 ? 116 PHE C CG  1 
ATOM   4443 C CD1 . PHE C 1 117 ? 63.74590 59.74185 93.62376  1.000 33.73014 ? 116 PHE C CD1 1 
ATOM   4444 C CD2 . PHE C 1 117 ? 64.81302 61.86726 93.89392  1.000 26.30220 ? 116 PHE C CD2 1 
ATOM   4445 C CE1 . PHE C 1 117 ? 64.33027 59.28234 94.79281  1.000 30.40894 ? 116 PHE C CE1 1 
ATOM   4446 C CE2 . PHE C 1 117 ? 65.40135 61.41988 95.05199  1.000 25.38526 ? 116 PHE C CE2 1 
ATOM   4447 C CZ  . PHE C 1 117 ? 65.15617 60.12241 95.50842  1.000 31.04207 ? 116 PHE C CZ  1 
ATOM   4448 N N   . TRP C 1 118 ? 60.76091 63.94173 90.91058  1.000 28.57302 ? 117 TRP C N   1 
ATOM   4449 C CA  . TRP C 1 118 ? 60.14500 64.52780 89.73334  1.000 28.85153 ? 117 TRP C CA  1 
ATOM   4450 C C   . TRP C 1 118 ? 61.17878 65.36619 89.00191  1.000 32.09152 ? 117 TRP C C   1 
ATOM   4451 O O   . TRP C 1 118 ? 62.00933 66.02270 89.63607  1.000 34.05063 ? 117 TRP C O   1 
ATOM   4452 C CB  . TRP C 1 118 ? 58.97446 65.40540 90.15401  1.000 28.56471 ? 117 TRP C CB  1 
ATOM   4453 C CG  . TRP C 1 118 ? 57.85919 64.69085 90.80152  1.000 30.25829 ? 117 TRP C CG  1 
ATOM   4454 C CD1 . TRP C 1 118 ? 57.93933 63.68948 91.72350  1.000 33.08592 ? 117 TRP C CD1 1 
ATOM   4455 C CD2 . TRP C 1 118 ? 56.46617 64.94119 90.59818  1.000 27.97503 ? 117 TRP C CD2 1 
ATOM   4456 N NE1 . TRP C 1 118 ? 56.67496 63.29237 92.09436  1.000 32.20955 ? 117 TRP C NE1 1 
ATOM   4457 C CE2 . TRP C 1 118 ? 55.75779 64.05253 91.41450  1.000 26.18217 ? 117 TRP C CE2 1 
ATOM   4458 C CE3 . TRP C 1 118 ? 55.75260 65.83325 89.79564  1.000 35.60859 ? 117 TRP C CE3 1 
ATOM   4459 C CZ2 . TRP C 1 118 ? 54.37415 64.02625 91.45178  1.000 30.18443 ? 117 TRP C CZ2 1 
ATOM   4460 C CZ3 . TRP C 1 118 ? 54.38174 65.80061 89.82952  1.000 32.84171 ? 117 TRP C CZ3 1 
ATOM   4461 C CH2 . TRP C 1 118 ? 53.70319 64.90663 90.65830  1.000 29.85484 ? 117 TRP C CH2 1 
ATOM   4462 N N   . GLY C 1 119 ? 61.18599 65.30898 87.66893  1.000 25.23656 ? 118 GLY C N   1 
ATOM   4463 C CA  . GLY C 1 119 ? 62.14094 66.13056 86.95946  1.000 30.76690 ? 118 GLY C CA  1 
ATOM   4464 C C   . GLY C 1 119 ? 61.68370 67.57550 86.87386  1.000 29.95889 ? 118 GLY C C   1 
ATOM   4465 O O   . GLY C 1 119 ? 60.64334 67.96734 87.40408  1.000 27.64359 ? 118 GLY C O   1 
ATOM   4466 N N   . GLN C 1 120 ? 62.35492 68.31912 86.00275  1.000 29.76795 ? 119 GLN C N   1 
ATOM   4467 C CA  . GLN C 1 120 ? 62.01473 69.72666 85.83770  1.000 36.39006 ? 119 GLN C CA  1 
ATOM   4468 C C   . GLN C 1 120 ? 60.72493 69.91201 85.05137  1.000 34.60069 ? 119 GLN C C   1 
ATOM   4469 O O   . GLN C 1 120 ? 60.08747 70.96132 85.17490  1.000 33.84989 ? 119 GLN C O   1 
ATOM   4470 C CB  . GLN C 1 120 ? 63.16707 70.47735 85.15798  1.000 36.26550 ? 119 GLN C CB  1 
ATOM   4471 C CG  . GLN C 1 120 ? 63.01341 72.00961 85.17525  1.000 43.60938 ? 119 GLN C CG  1 
ATOM   4472 C CD  . GLN C 1 120 ? 62.59130 72.62656 83.82540  1.000 41.14005 ? 119 GLN C CD  1 
ATOM   4473 O OE1 . GLN C 1 120 ? 63.06409 72.22854 82.75621  1.000 36.08655 ? 119 GLN C OE1 1 
ATOM   4474 N NE2 . GLN C 1 120 ? 61.68095 73.59771 83.88491  1.000 37.13022 ? 119 GLN C NE2 1 
ATOM   4475 N N   . GLY C 1 121 ? 60.30800 68.91531 84.28171  1.000 35.36569 ? 120 GLY C N   1 
ATOM   4476 C CA  . GLY C 1 121 ? 59.16851 69.08304 83.40811  1.000 36.27257 ? 120 GLY C CA  1 
ATOM   4477 C C   . GLY C 1 121 ? 59.58484 69.48975 82.00060  1.000 36.98768 ? 120 GLY C C   1 
ATOM   4478 O O   . GLY C 1 121 ? 60.71663 69.90983 81.74164  1.000 37.93829 ? 120 GLY C O   1 
ATOM   4479 N N   . THR C 1 122 ? 58.68478 69.25786 81.05749  1.000 30.94303 ? 121 THR C N   1 
ATOM   4480 C CA  . THR C 1 122 ? 58.85674 69.76280 79.70730  1.000 30.51987 ? 121 THR C CA  1 
ATOM   4481 C C   . THR C 1 122 ? 57.49985 70.31543 79.28038  1.000 31.25221 ? 121 THR C C   1 
ATOM   4482 O O   . THR C 1 122 ? 56.48045 69.63739 79.43370  1.000 31.97071 ? 121 THR C O   1 
ATOM   4483 C CB  . THR C 1 122 ? 59.40660 68.64551 78.77666  1.000 34.23223 ? 121 THR C CB  1 
ATOM   4484 O OG1 . THR C 1 122 ? 59.89229 69.19415 77.54232  1.000 39.29159 ? 121 THR C OG1 1 
ATOM   4485 C CG2 . THR C 1 122 ? 58.38542 67.55261 78.49933  1.000 24.50236 ? 121 THR C CG2 1 
ATOM   4486 N N   . LEU C 1 123 ? 57.46993 71.56239 78.81007  1.000 29.79781 ? 122 LEU C N   1 
ATOM   4487 C CA  . LEU C 1 123 ? 56.20338 72.22423 78.51605  1.000 25.74847 ? 122 LEU C CA  1 
ATOM   4488 C C   . LEU C 1 123 ? 55.71536 71.79245 77.14757  1.000 27.36675 ? 122 LEU C C   1 
ATOM   4489 O O   . LEU C 1 123 ? 56.49818 71.74925 76.19108  1.000 27.75516 ? 122 LEU C O   1 
ATOM   4490 C CB  . LEU C 1 123 ? 56.35768 73.75047 78.56124  1.000 27.32112 ? 122 LEU C CB  1 
ATOM   4491 C CG  . LEU C 1 123 ? 55.24987 74.70003 78.06698  1.000 23.29240 ? 122 LEU C CG  1 
ATOM   4492 C CD1 . LEU C 1 123 ? 54.06080 74.81967 79.01303  1.000 20.92177 ? 122 LEU C CD1 1 
ATOM   4493 C CD2 . LEU C 1 123 ? 55.84481 76.07532 77.83514  1.000 26.45281 ? 122 LEU C CD2 1 
ATOM   4494 N N   . VAL C 1 124 ? 54.43711 71.44007 77.05050  1.000 24.23439 ? 123 VAL C N   1 
ATOM   4495 C CA  . VAL C 1 124 ? 53.80646 71.22894 75.75483  1.000 24.54085 ? 123 VAL C CA  1 
ATOM   4496 C C   . VAL C 1 124 ? 52.64840 72.20424 75.62433  1.000 26.25317 ? 123 VAL C C   1 
ATOM   4497 O O   . VAL C 1 124 ? 51.68510 72.12107 76.39301  1.000 26.01779 ? 123 VAL C O   1 
ATOM   4498 C CB  . VAL C 1 124 ? 53.33450 69.78151 75.56936  1.000 27.14549 ? 123 VAL C CB  1 
ATOM   4499 C CG1 . VAL C 1 124 ? 52.43140 69.67172 74.33576  1.000 26.07588 ? 123 VAL C CG1 1 
ATOM   4500 C CG2 . VAL C 1 124 ? 54.52724 68.85810 75.45779  1.000 19.91872 ? 123 VAL C CG2 1 
ATOM   4501 N N   . THR C 1 125 ? 52.72732 73.10109 74.63053  1.000 28.80455 ? 124 THR C N   1 
ATOM   4502 C CA  . THR C 1 125 ? 51.66063 74.04578 74.31108  1.000 31.14090 ? 124 THR C CA  1 
ATOM   4503 C C   . THR C 1 125 ? 51.03184 73.61370 72.99836  1.000 34.93815 ? 124 THR C C   1 
ATOM   4504 O O   . THR C 1 125 ? 51.73728 73.37317 72.01488  1.000 33.76313 ? 124 THR C O   1 
ATOM   4505 C CB  . THR C 1 125 ? 52.15892 75.49118 74.15997  1.000 34.11659 ? 124 THR C CB  1 
ATOM   4506 O OG1 . THR C 1 125 ? 53.03954 75.83744 75.23271  1.000 42.94088 ? 124 THR C OG1 1 
ATOM   4507 C CG2 . THR C 1 125 ? 50.98688 76.46879 74.15647  1.000 27.62059 ? 124 THR C CG2 1 
ATOM   4508 N N   . VAL C 1 126 ? 49.70699 73.57315 72.96619  1.000 34.06069 ? 125 VAL C N   1 
ATOM   4509 C CA  . VAL C 1 126 ? 48.97951 73.10434 71.80475  1.000 29.44259 ? 125 VAL C CA  1 
ATOM   4510 C C   . VAL C 1 126 ? 48.14626 74.27262 71.31862  1.000 35.20459 ? 125 VAL C C   1 
ATOM   4511 O O   . VAL C 1 126 ? 47.34908 74.82733 72.08160  1.000 37.51681 ? 125 VAL C O   1 
ATOM   4512 C CB  . VAL C 1 126 ? 48.09208 71.89107 72.13246  1.000 32.71253 ? 125 VAL C CB  1 
ATOM   4513 C CG1 . VAL C 1 126 ? 47.53102 71.27622 70.85086  1.000 33.99030 ? 125 VAL C CG1 1 
ATOM   4514 C CG2 . VAL C 1 126 ? 48.84410 70.85567 72.96312  1.000 29.06042 ? 125 VAL C CG2 1 
ATOM   4515 N N   . SER C 1 127 ? 48.35749 74.65951 70.06182  1.000 37.38223 ? 126 SER C N   1 
ATOM   4516 C CA  . SER C 1 127 ? 47.77798 75.85411 69.47692  1.000 32.74635 ? 126 SER C CA  1 
ATOM   4517 C C   . SER C 1 127 ? 46.25953 75.76157 69.43077  1.000 35.44433 ? 126 SER C C   1 
ATOM   4518 O O   . SER C 1 127 ? 45.66092 74.71580 69.66946  1.000 35.20723 ? 126 SER C O   1 
ATOM   4519 C CB  . SER C 1 127 ? 48.29330 76.05209 68.05800  1.000 37.33580 ? 126 SER C CB  1 
ATOM   4520 O OG  . SER C 1 127 ? 49.69577 75.93096 68.01686  1.000 39.33637 ? 126 SER C OG  1 
ATOM   4521 N N   . SER C 1 128 ? 45.64307 76.87563 69.05335  1.000 40.67578 ? 127 SER C N   1 
ATOM   4522 C CA  . SER C 1 128 ? 44.20144 76.92393 68.85957  1.000 44.41330 ? 127 SER C CA  1 
ATOM   4523 C C   . SER C 1 128 ? 43.77916 76.37212 67.50118  1.000 35.20077 ? 127 SER C C   1 
ATOM   4524 O O   . SER C 1 128 ? 42.68539 75.82275 67.36741  1.000 28.81821 ? 127 SER C O   1 
ATOM   4525 C CB  . SER C 1 128 ? 43.70459 78.35683 69.02024  1.000 47.91179 ? 127 SER C CB  1 
ATOM   4526 O OG  . SER C 1 128 ? 43.83383 78.76424 70.37218  1.000 53.30604 ? 127 SER C OG  1 
ATOM   4527 N N   . GLN C 1 149 ? 34.00146 67.29310 89.94115  1.000 66.52453 ? 148 GLN C N   1 
ATOM   4528 C CA  . GLN C 1 149 ? 33.55304 66.17166 90.75846  1.000 66.16437 ? 148 GLN C CA  1 
ATOM   4529 C C   . GLN C 1 149 ? 34.66590 65.13668 90.85348  1.000 70.12853 ? 148 GLN C C   1 
ATOM   4530 O O   . GLN C 1 149 ? 34.42552 63.92523 90.74655  1.000 64.96686 ? 148 GLN C O   1 
ATOM   4531 C CB  . GLN C 1 149 ? 32.28091 65.54917 90.17575  1.000 62.26136 ? 148 GLN C CB  1 
ATOM   4532 N N   . SER C 1 150 ? 35.88552 65.63884 91.05891  1.000 66.92776 ? 149 SER C N   1 
ATOM   4533 C CA  . SER C 1 150 ? 37.08856 64.81609 91.07682  1.000 58.44457 ? 149 SER C CA  1 
ATOM   4534 C C   . SER C 1 150 ? 38.30549 65.66366 91.42794  1.000 65.76377 ? 149 SER C C   1 
ATOM   4535 O O   . SER C 1 150 ? 38.99304 66.16263 90.52983  1.000 72.28378 ? 149 SER C O   1 
ATOM   4536 C CB  . SER C 1 150 ? 37.29749 64.13562 89.72039  1.000 58.07895 ? 149 SER C CB  1 
ATOM   4537 N N   . ALA C 1 151 ? 38.57573 65.82884 92.72327  1.000 60.31014 ? 150 ALA C N   1 
ATOM   4538 C CA  . ALA C 1 151 ? 39.69781 66.61000 93.24005  1.000 53.42290 ? 150 ALA C CA  1 
ATOM   4539 C C   . ALA C 1 151 ? 39.63187 66.53735 94.76142  1.000 46.17041 ? 150 ALA C C   1 
ATOM   4540 O O   . ALA C 1 151 ? 38.68656 65.98773 95.33503  1.000 47.77819 ? 150 ALA C O   1 
ATOM   4541 C CB  . ALA C 1 151 ? 39.67300 68.07764 92.77282  1.000 48.30633 ? 150 ALA C CB  1 
ATOM   4542 N N   . LEU C 1 152 ? 40.65568 67.08447 95.40900  1.000 38.17452 ? 151 LEU C N   1 
ATOM   4543 C CA  . LEU C 1 152 ? 40.61812 67.34896 96.83900  1.000 34.73351 ? 151 LEU C CA  1 
ATOM   4544 C C   . LEU C 1 152 ? 40.55559 68.85606 97.07604  1.000 38.21411 ? 151 LEU C C   1 
ATOM   4545 O O   . LEU C 1 152 ? 41.09362 69.64831 96.29847  1.000 36.14356 ? 151 LEU C O   1 
ATOM   4546 C CB  . LEU C 1 152 ? 41.83007 66.74836 97.54912  1.000 27.43000 ? 151 LEU C CB  1 
ATOM   4547 C CG  . LEU C 1 152 ? 42.22688 65.35977 97.05387  1.000 27.98428 ? 151 LEU C CG  1 
ATOM   4548 C CD1 . LEU C 1 152 ? 43.57415 64.93357 97.63987  1.000 21.03518 ? 151 LEU C CD1 1 
ATOM   4549 C CD2 . LEU C 1 152 ? 41.11916 64.35037 97.34603  1.000 20.77903 ? 151 LEU C CD2 1 
ATOM   4550 N N   . THR C 1 153 ? 39.90273 69.25399 98.15776  1.000 29.25280 ? 152 THR C N   1 
ATOM   4551 C CA  . THR C 1 153 ? 39.64364 70.65881 98.39691  1.000 27.03935 ? 152 THR C CA  1 
ATOM   4552 C C   . THR C 1 153 ? 40.76629 71.25391 99.23003  1.000 27.60674 ? 152 THR C C   1 
ATOM   4553 O O   . THR C 1 153 ? 41.12351 70.73179 100.28666 1.000 31.55922 ? 152 THR C O   1 
ATOM   4554 C CB  . THR C 1 153 ? 38.31283 70.85585 99.11527  1.000 27.53387 ? 152 THR C CB  1 
ATOM   4555 O OG1 . THR C 1 153 ? 37.23158 70.62307 98.20475  1.000 27.53022 ? 152 THR C OG1 1 
ATOM   4556 C CG2 . THR C 1 153 ? 38.23015 72.26237 99.65145  1.000 24.98706 ? 152 THR C CG2 1 
ATOM   4557 N N   . GLN C 1 154 ? 41.30938 72.35882 98.75144  1.000 28.34358 ? 153 GLN C N   1 
ATOM   4558 C CA  . GLN C 1 154 ? 42.48750 72.91633 99.30315  1.000 24.32618 ? 153 GLN C CA  1 
ATOM   4559 C C   . GLN C 1 154 ? 42.33244 74.43718 99.23656  1.000 30.68692 ? 153 GLN C C   1 
ATOM   4560 O O   . GLN C 1 154 ? 42.05032 74.99017 98.15072  1.000 32.76992 ? 153 GLN C O   1 
ATOM   4561 C CB  . GLN C 1 154 ? 43.67835 72.40843 98.48979  1.000 28.62018 ? 153 GLN C CB  1 
ATOM   4562 C CG  . GLN C 1 154 ? 44.97568 72.33233 99.22166  1.000 28.68896 ? 153 GLN C CG  1 
ATOM   4563 C CD  . GLN C 1 154 ? 46.12067 71.87809 98.33355  1.000 30.13207 ? 153 GLN C CD  1 
ATOM   4564 O OE1 . GLN C 1 154 ? 45.93478 71.49366 97.17503  1.000 29.23766 ? 153 GLN C OE1 1 
ATOM   4565 N NE2 . GLN C 1 154 ? 47.32292 71.97214 98.86195  1.000 30.62970 ? 153 GLN C NE2 1 
ATOM   4566 N N   . PRO C 1 155 ? 42.50666 75.14177 100.34911 1.000 34.86006 ? 154 PRO C N   1 
ATOM   4567 C CA  . PRO C 1 155 ? 42.31473 76.59617 100.34150 1.000 26.42133 ? 154 PRO C CA  1 
ATOM   4568 C C   . PRO C 1 155 ? 43.25110 77.30154 99.36133  1.000 27.53312 ? 154 PRO C C   1 
ATOM   4569 O O   . PRO C 1 155 ? 44.40287 76.90162 99.17890  1.000 26.18716 ? 154 PRO C O   1 
ATOM   4570 C CB  . PRO C 1 155 ? 42.61713 76.98291 101.78914 1.000 27.18568 ? 154 PRO C CB  1 
ATOM   4571 C CG  . PRO C 1 155 ? 43.63639 75.98680 102.21150 1.000 26.39570 ? 154 PRO C CG  1 
ATOM   4572 C CD  . PRO C 1 155 ? 43.16113 74.69294 101.59243 1.000 33.09406 ? 154 PRO C CD  1 
ATOM   4573 N N   . ALA C 1 156 ? 42.71330 78.31617 98.66569  1.000 28.34815 ? 155 ALA C N   1 
ATOM   4574 C CA  . ALA C 1 156 ? 43.48306 79.02283 97.63855  1.000 23.12122 ? 155 ALA C CA  1 
ATOM   4575 C C   . ALA C 1 156 ? 44.75183 79.65503 98.19885  1.000 25.24364 ? 155 ALA C C   1 
ATOM   4576 O O   . ALA C 1 156 ? 45.77350 79.73119 97.50416  1.000 28.55593 ? 155 ALA C O   1 
ATOM   4577 C CB  . ALA C 1 156 ? 42.62429 80.09856 96.98846  1.000 17.28757 ? 155 ALA C CB  1 
ATOM   4578 N N   . SER C 1 157 ? 44.70823 80.13223 99.43956  1.000 23.38724 ? 156 SER C N   1 
ATOM   4579 C CA  . SER C 1 157 ? 45.79512 80.95587 99.94845  1.000 26.70563 ? 156 SER C CA  1 
ATOM   4580 C C   . SER C 1 157 ? 45.92185 80.86520 101.46506 1.000 25.83556 ? 156 SER C C   1 
ATOM   4581 O O   . SER C 1 157 ? 44.93954 80.70817 102.19754 1.000 23.69674 ? 156 SER C O   1 
ATOM   4582 C CB  . SER C 1 157 ? 45.59974 82.41485 99.54234  1.000 29.19278 ? 156 SER C CB  1 
ATOM   4583 O OG  . SER C 1 157 ? 44.23798 82.75850 99.71071  1.000 36.06919 ? 156 SER C OG  1 
ATOM   4584 N N   . ALA C 1 158 ? 47.15744 80.98583 101.92323 1.000 24.23463 ? 157 ALA C N   1 
ATOM   4585 C CA  . ALA C 1 158 ? 47.45824 81.03023 103.34051 1.000 29.57931 ? 157 ALA C CA  1 
ATOM   4586 C C   . ALA C 1 158 ? 48.77278 81.77962 103.48689 1.000 32.51523 ? 157 ALA C C   1 
ATOM   4587 O O   . ALA C 1 158 ? 49.54264 81.89767 102.52565 1.000 32.77223 ? 157 ALA C O   1 
ATOM   4588 C CB  . ALA C 1 158 ? 47.51842 79.62918 103.96171 1.000 31.04609 ? 157 ALA C CB  1 
ATOM   4589 N N   . SER C 1 159 ? 49.01367 82.32602 104.68043 1.000 30.32113 ? 158 SER C N   1 
ATOM   4590 C CA  . SER C 1 159 ? 50.20227 83.14529 104.85914 1.000 36.00727 ? 158 SER C CA  1 
ATOM   4591 C C   . SER C 1 159 ? 50.65976 83.10609 106.30636 1.000 31.70103 ? 158 SER C C   1 
ATOM   4592 O O   . SER C 1 159 ? 49.94049 82.65949 107.20173 1.000 30.79256 ? 158 SER C O   1 
ATOM   4593 C CB  . SER C 1 159 ? 49.96816 84.59543 104.41530 1.000 33.20808 ? 158 SER C CB  1 
ATOM   4594 O OG  . SER C 1 159 ? 49.23994 85.31177 105.39357 1.000 28.47324 ? 158 SER C OG  1 
ATOM   4595 N N   . GLY C 1 160 ? 51.89358 83.56993 106.49816 1.000 29.31632 ? 159 GLY C N   1 
ATOM   4596 C CA  . GLY C 1 160 ? 52.55457 83.68469 107.78496 1.000 30.10151 ? 159 GLY C CA  1 
ATOM   4597 C C   . GLY C 1 160 ? 53.80418 84.52158 107.61918 1.000 30.85845 ? 159 GLY C C   1 
ATOM   4598 O O   . GLY C 1 160 ? 54.22254 84.84489 106.50547 1.000 37.53405 ? 159 GLY C O   1 
ATOM   4599 N N   . SER C 1 161 ? 54.39605 84.87507 108.73680 1.000 29.87036 ? 160 SER C N   1 
ATOM   4600 C CA  . SER C 1 161 ? 55.64695 85.61513 108.75663 1.000 35.76736 ? 160 SER C CA  1 
ATOM   4601 C C   . SER C 1 161 ? 56.80543 84.75672 109.24858 1.000 34.38249 ? 160 SER C C   1 
ATOM   4602 O O   . SER C 1 161 ? 56.59787 83.72789 109.89459 1.000 31.50162 ? 160 SER C O   1 
ATOM   4603 C CB  . SER C 1 161 ? 55.51043 86.89112 109.60304 1.000 35.23145 ? 160 SER C CB  1 
ATOM   4604 O OG  . SER C 1 161 ? 54.63437 87.81296 108.95159 1.000 41.55078 ? 160 SER C OG  1 
ATOM   4605 N N   . PRO C 1 162 ? 58.03993 85.12317 108.90776 1.000 36.59419 ? 161 PRO C N   1 
ATOM   4606 C CA  . PRO C 1 162 ? 59.18972 84.29839 109.29872 1.000 35.63317 ? 161 PRO C CA  1 
ATOM   4607 C C   . PRO C 1 162 ? 59.15628 83.93601 110.77351 1.000 37.42654 ? 161 PRO C C   1 
ATOM   4608 O O   . PRO C 1 162 ? 58.94294 84.78960 111.63783 1.000 43.01721 ? 161 PRO C O   1 
ATOM   4609 C CB  . PRO C 1 162 ? 60.38399 85.19617 108.96775 1.000 37.90023 ? 161 PRO C CB  1 
ATOM   4610 C CG  . PRO C 1 162 ? 59.91630 86.03024 107.79778 1.000 33.44360 ? 161 PRO C CG  1 
ATOM   4611 C CD  . PRO C 1 162 ? 58.42935 86.23467 108.01062 1.000 38.57877 ? 161 PRO C CD  1 
ATOM   4612 N N   . GLY C 1 163 ? 59.34801 82.64919 111.05697 1.000 31.95045 ? 162 GLY C N   1 
ATOM   4613 C CA  . GLY C 1 163 ? 59.25358 82.13152 112.39521 1.000 34.34546 ? 162 GLY C CA  1 
ATOM   4614 C C   . GLY C 1 163 ? 57.86894 81.65370 112.77771 1.000 34.85553 ? 162 GLY C C   1 
ATOM   4615 O O   . GLY C 1 163 ? 57.73783 80.74548 113.60779 1.000 44.62815 ? 162 GLY C O   1 
ATOM   4616 N N   . GLN C 1 164 ? 56.83380 82.27495 112.23134 1.000 34.12534 ? 163 GLN C N   1 
ATOM   4617 C CA  . GLN C 1 164 ? 55.48964 81.79680 112.46799 1.000 29.98534 ? 163 GLN C CA  1 
ATOM   4618 C C   . GLN C 1 164 ? 55.28924 80.44212 111.79653 1.000 35.30682 ? 163 GLN C C   1 
ATOM   4619 O O   . GLN C 1 164 ? 56.07005 80.02172 110.93510 1.000 33.55167 ? 163 GLN C O   1 
ATOM   4620 C CB  . GLN C 1 164 ? 54.47357 82.81821 111.94878 1.000 30.50298 ? 163 GLN C CB  1 
ATOM   4621 C CG  . GLN C 1 164 ? 54.48884 84.08277 112.77358 1.000 32.16177 ? 163 GLN C CG  1 
ATOM   4622 C CD  . GLN C 1 164 ? 53.48962 85.11613 112.33777 1.000 33.28246 ? 163 GLN C CD  1 
ATOM   4623 O OE1 . GLN C 1 164 ? 53.05679 85.15774 111.19035 1.000 41.40266 ? 163 GLN C OE1 1 
ATOM   4624 N NE2 . GLN C 1 164 ? 53.07120 85.93464 113.28263 1.000 31.98245 ? 163 GLN C NE2 1 
ATOM   4625 N N   . SER C 1 165 ? 54.23686 79.74674 112.21803 1.000 34.85919 ? 164 SER C N   1 
ATOM   4626 C CA  . SER C 1 165 ? 53.80048 78.52925 111.55627 1.000 31.44699 ? 164 SER C CA  1 
ATOM   4627 C C   . SER C 1 165 ? 52.55542 78.81634 110.71699 1.000 38.59513 ? 164 SER C C   1 
ATOM   4628 O O   . SER C 1 165 ? 51.92108 79.87836 110.82111 1.000 30.54794 ? 164 SER C O   1 
ATOM   4629 C CB  . SER C 1 165 ? 53.53428 77.40286 112.55772 1.000 34.16625 ? 164 SER C CB  1 
ATOM   4630 O OG  . SER C 1 165 ? 52.23151 77.48776 113.09898 1.000 39.63788 ? 164 SER C OG  1 
ATOM   4631 N N   . VAL C 1 166 ? 52.19755 77.82322 109.89725 1.000 35.68260 ? 165 VAL C N   1 
ATOM   4632 C CA  . VAL C 1 166 ? 51.04135 77.88832 109.00978 1.000 34.04058 ? 165 VAL C CA  1 
ATOM   4633 C C   . VAL C 1 166 ? 50.51046 76.47077 108.84140 1.000 31.50686 ? 165 VAL C C   1 
ATOM   4634 O O   . VAL C 1 166 ? 51.26263 75.49999 108.92786 1.000 40.74002 ? 165 VAL C O   1 
ATOM   4635 C CB  . VAL C 1 166 ? 51.42660 78.52590 107.65224 1.000 31.03374 ? 165 VAL C CB  1 
ATOM   4636 C CG1 . VAL C 1 166 ? 52.33599 77.59362 106.88460 1.000 35.62588 ? 165 VAL C CG1 1 
ATOM   4637 C CG2 . VAL C 1 166 ? 50.19276 78.86530 106.83631 1.000 33.68915 ? 165 VAL C CG2 1 
ATOM   4638 N N   . THR C 1 167 ? 49.20889 76.34215 108.60367 1.000 31.84654 ? 166 THR C N   1 
ATOM   4639 C CA  . THR C 1 167 ? 48.60835 75.02716 108.41351 1.000 33.94957 ? 166 THR C CA  1 
ATOM   4640 C C   . THR C 1 167 ? 47.69759 75.04380 107.19424 1.000 36.14885 ? 166 THR C C   1 
ATOM   4641 O O   . THR C 1 167 ? 46.85272 75.93751 107.04652 1.000 35.35187 ? 166 THR C O   1 
ATOM   4642 C CB  . THR C 1 167 ? 47.86016 74.58378 109.67492 1.000 35.56097 ? 166 THR C CB  1 
ATOM   4643 O OG1 . THR C 1 167 ? 48.82453 74.25968 110.68029 1.000 35.16269 ? 166 THR C OG1 1 
ATOM   4644 C CG2 . THR C 1 167 ? 46.97521 73.35796 109.41612 1.000 28.27595 ? 166 THR C CG2 1 
ATOM   4645 N N   . ILE C 1 168 ? 47.86757 74.02473 106.34746 1.000 39.90343 ? 167 ILE C N   1 
ATOM   4646 C CA  . ILE C 1 168 ? 47.16558 73.86856 105.07794 1.000 36.90323 ? 167 ILE C CA  1 
ATOM   4647 C C   . ILE C 1 168 ? 46.22973 72.67228 105.17623 1.000 35.29773 ? 167 ILE C C   1 
ATOM   4648 O O   . ILE C 1 168 ? 46.58456 71.65040 105.76621 1.000 34.51371 ? 167 ILE C O   1 
ATOM   4649 C CB  . ILE C 1 168 ? 48.15810 73.70392 103.90569 1.000 34.66402 ? 167 ILE C CB  1 
ATOM   4650 C CG1 . ILE C 1 168 ? 49.11613 74.87965 103.87140 1.000 32.19915 ? 167 ILE C CG1 1 
ATOM   4651 C CG2 . ILE C 1 168 ? 47.43979 73.68900 102.58574 1.000 32.97623 ? 167 ILE C CG2 1 
ATOM   4652 C CD1 . ILE C 1 168 ? 48.40007 76.16655 103.71353 1.000 39.18669 ? 167 ILE C CD1 1 
ATOM   4653 N N   . THR C 1 169 ? 45.04007 72.80709 104.58732 1.000 37.94006 ? 168 THR C N   1 
ATOM   4654 C CA  . THR C 1 169 ? 43.97849 71.81428 104.60579 1.000 31.23061 ? 168 THR C CA  1 
ATOM   4655 C C   . THR C 1 169 ? 43.85955 71.06107 103.28735 1.000 36.64181 ? 168 THR C C   1 
ATOM   4656 O O   . THR C 1 169 ? 44.14847 71.58886 102.20704 1.000 32.38934 ? 168 THR C O   1 
ATOM   4657 C CB  . THR C 1 169 ? 42.64982 72.50433 104.90415 1.000 30.40216 ? 168 THR C CB  1 
ATOM   4658 O OG1 . THR C 1 169 ? 42.80899 73.30972 106.06696 1.000 36.10482 ? 168 THR C OG1 1 
ATOM   4659 C CG2 . THR C 1 169 ? 41.52650 71.51154 105.10730 1.000 40.88275 ? 168 THR C CG2 1 
ATOM   4660 N N   . CYS C 1 170 ? 43.44916 69.79968 103.40176 1.000 35.29657 ? 169 CYS C N   1 
ATOM   4661 C CA  . CYS C 1 170 ? 43.18562 68.95934 102.24553 1.000 30.43926 ? 169 CYS C CA  1 
ATOM   4662 C C   . CYS C 1 170 ? 42.00702 68.05856 102.58170 1.000 34.60255 ? 169 CYS C C   1 
ATOM   4663 O O   . CYS C 1 170 ? 42.16222 67.10518 103.34458 1.000 42.12327 ? 169 CYS C O   1 
ATOM   4664 C CB  . CYS C 1 170 ? 44.41140 68.14460 101.87307 1.000 27.14022 ? 169 CYS C CB  1 
ATOM   4665 S SG  . CYS C 1 170 ? 44.16075 67.22107 100.36791 1.000 31.62442 ? 169 CYS C SG  1 
ATOM   4666 N N   . THR C 1 171 ? 40.84202 68.33223 102.01670 1.000 32.32855 ? 170 THR C N   1 
ATOM   4667 C CA  . THR C 1 171 ? 39.64283 67.57565 102.33712 1.000 29.36504 ? 170 THR C CA  1 
ATOM   4668 C C   . THR C 1 171 ? 39.27889 66.69122 101.16033 1.000 30.62006 ? 170 THR C C   1 
ATOM   4669 O O   . THR C 1 171 ? 39.06592 67.19196 100.05445 1.000 24.20647 ? 170 THR C O   1 
ATOM   4670 C CB  . THR C 1 171 ? 38.47976 68.49413 102.68184 1.000 32.69377 ? 170 THR C CB  1 
ATOM   4671 O OG1 . THR C 1 171 ? 38.69624 69.06484 103.98256 1.000 34.45435 ? 170 THR C OG1 1 
ATOM   4672 C CG2 . THR C 1 171 ? 37.19035 67.70186 102.68243 1.000 23.47297 ? 170 THR C CG2 1 
ATOM   4673 N N   . GLY C 1 172 ? 39.23191 65.37767 101.39873 1.000 32.76237 ? 171 GLY C N   1 
ATOM   4674 C CA  . GLY C 1 172 ? 38.80343 64.45081 100.37420 1.000 27.47285 ? 171 GLY C CA  1 
ATOM   4675 C C   . GLY C 1 172 ? 37.57420 63.66485 100.78238 1.000 34.52554 ? 171 GLY C C   1 
ATOM   4676 O O   . GLY C 1 172 ? 36.65893 64.24302 101.36748 1.000 32.16979 ? 171 GLY C O   1 
ATOM   4677 N N   . SER C 1 173 ? 37.52812 62.36423 100.47437 1.000 45.43082 ? 172 SER C N   1 
ATOM   4678 C CA  . SER C 1 173 ? 36.36759 61.53194 100.77290 1.000 43.24456 ? 172 SER C CA  1 
ATOM   4679 C C   . SER C 1 173 ? 36.83231 60.19758 101.34568 1.000 36.42824 ? 172 SER C C   1 
ATOM   4680 O O   . SER C 1 173 ? 38.02225 59.99255 101.61449 1.000 37.36497 ? 172 SER C O   1 
ATOM   4681 C CB  . SER C 1 173 ? 35.48991 61.36138 99.52694  1.000 46.84197 ? 172 SER C CB  1 
ATOM   4682 O OG  . SER C 1 173 ? 36.17065 60.65110 98.51679  1.000 42.51686 ? 172 SER C OG  1 
ATOM   4683 N N   . SER C 1 174 ? 35.88011 59.26053 101.47292 1.000 36.43605 ? 173 SER C N   1 
ATOM   4684 C CA  . SER C 1 174 ? 36.24586 57.90659 101.88454 1.000 33.50212 ? 173 SER C CA  1 
ATOM   4685 C C   . SER C 1 174 ? 37.18614 57.26868 100.88902 1.000 38.60705 ? 173 SER C C   1 
ATOM   4686 O O   . SER C 1 174 ? 38.03206 56.45553 101.26069 1.000 37.37306 ? 173 SER C O   1 
ATOM   4687 C CB  . SER C 1 174 ? 35.02321 57.01432 101.98582 1.000 19.07629 ? 173 SER C CB  1 
ATOM   4688 O OG  . SER C 1 174 ? 34.10974 57.44628 102.96051 1.000 38.57474 ? 173 SER C OG  1 
ATOM   4689 N N   . SER C 1 175 ? 37.02112 57.57638 99.62017  1.000 40.59425 ? 174 SER C N   1 
ATOM   4690 C CA  . SER C 1 175 ? 37.87215 56.96358 98.63131  1.000 31.56346 ? 174 SER C CA  1 
ATOM   4691 C C   . SER C 1 175 ? 39.25063 57.57858 98.58907  1.000 32.22545 ? 174 SER C C   1 
ATOM   4692 O O   . SER C 1 175 ? 40.05026 57.15659 97.76352  1.000 33.06343 ? 174 SER C O   1 
ATOM   4693 C CB  . SER C 1 175 ? 37.20915 57.05723 97.26707  1.000 33.35600 ? 174 SER C CB  1 
ATOM   4694 O OG  . SER C 1 175 ? 35.99341 56.32213 97.34163  1.000 35.12812 ? 174 SER C OG  1 
ATOM   4695 N N   . ASP C 1 176 ? 39.56665 58.58719 99.41107  1.000 37.21874 ? 175 ASP C N   1 
ATOM   4696 C CA  . ASP C 1 176 ? 40.82195 59.18932 99.03014  1.000 40.62735 ? 175 ASP C CA  1 
ATOM   4697 C C   . ASP C 1 176 ? 41.61211 59.35291 100.31827 1.000 33.23254 ? 175 ASP C C   1 
ATOM   4698 O O   . ASP C 1 176 ? 42.14632 58.39003 100.88680 1.000 32.10900 ? 175 ASP C O   1 
ATOM   4699 C CB  . ASP C 1 176 ? 40.72747 60.58496 98.38378  1.000 36.95596 ? 175 ASP C CB  1 
ATOM   4700 C CG  . ASP C 1 176 ? 39.66960 60.73781 97.36800  1.000 40.45384 ? 175 ASP C CG  1 
ATOM   4701 O OD1 . ASP C 1 176 ? 39.14621 59.69005 96.98946  1.000 51.75157 ? 175 ASP C OD1 1 
ATOM   4702 O OD2 . ASP C 1 176 ? 39.49671 61.84228 96.75176  1.000 53.38694 ? 175 ASP C OD2 1 
ATOM   4703 N N   . VAL C 1 177 ? 41.61171 60.58528 100.81161 1.000 33.02845 ? 176 VAL C N   1 
ATOM   4704 C CA  . VAL C 1 177 ? 42.37936 60.91130 102.00045 1.000 35.19554 ? 176 VAL C CA  1 
ATOM   4705 C C   . VAL C 1 177 ? 41.93176 60.02672 103.14264 1.000 36.97020 ? 176 VAL C C   1 
ATOM   4706 O O   . VAL C 1 177 ? 42.75225 59.46899 103.87817 1.000 33.36420 ? 176 VAL C O   1 
ATOM   4707 C CB  . VAL C 1 177 ? 42.24388 62.40475 102.34013 1.000 32.71970 ? 176 VAL C CB  1 
ATOM   4708 C CG1 . VAL C 1 177 ? 43.00390 62.71312 103.58131 1.000 32.63953 ? 176 VAL C CG1 1 
ATOM   4709 C CG2 . VAL C 1 177 ? 42.71062 63.25590 101.18305 1.000 30.19143 ? 176 VAL C CG2 1 
ATOM   4710 N N   . GLY C 1 178 ? 40.62295 59.84207 103.27359 1.000 34.49191 ? 177 GLY C N   1 
ATOM   4711 C CA  . GLY C 1 178 ? 40.09096 59.02032 104.33269 1.000 29.07145 ? 177 GLY C CA  1 
ATOM   4712 C C   . GLY C 1 178 ? 40.05421 57.53701 104.04845 1.000 31.75412 ? 177 GLY C C   1 
ATOM   4713 O O   . GLY C 1 178 ? 39.47464 56.76635 104.81617 1.000 30.80425 ? 177 GLY C O   1 
ATOM   4714 N N   . GLY C 1 179 ? 40.61901 57.10651 102.93213 1.000 29.72630 ? 178 GLY C N   1 
ATOM   4715 C CA  . GLY C 1 179 ? 40.58190 55.70203 102.61265 1.000 32.11333 ? 178 GLY C CA  1 
ATOM   4716 C C   . GLY C 1 179 ? 41.90323 54.97162 102.69737 1.000 36.37741 ? 178 GLY C C   1 
ATOM   4717 O O   . GLY C 1 179 ? 41.91780 53.73943 102.74132 1.000 42.83930 ? 178 GLY C O   1 
ATOM   4718 N N   . TYR C 1 180 ? 43.01234 55.70321 102.71687 1.000 35.03004 ? 179 TYR C N   1 
ATOM   4719 C CA  . TYR C 1 180 ? 44.33827 55.11109 102.66219 1.000 27.58906 ? 179 TYR C CA  1 
ATOM   4720 C C   . TYR C 1 180 ? 45.24753 55.93213 103.53911 1.000 30.89405 ? 179 TYR C C   1 
ATOM   4721 O O   . TYR C 1 180 ? 44.91247 57.05387 103.93464 1.000 36.48102 ? 179 TYR C O   1 
ATOM   4722 C CB  . TYR C 1 180 ? 44.90658 55.07802 101.23844 1.000 31.54561 ? 179 TYR C CB  1 
ATOM   4723 C CG  . TYR C 1 180 ? 44.02798 54.36377 100.24969 1.000 34.92655 ? 179 TYR C CG  1 
ATOM   4724 C CD1 . TYR C 1 180 ? 42.99811 55.02693 99.60322  1.000 36.08702 ? 179 TYR C CD1 1 
ATOM   4725 C CD2 . TYR C 1 180 ? 44.22687 53.02827 99.96280  1.000 36.45633 ? 179 TYR C CD2 1 
ATOM   4726 C CE1 . TYR C 1 180 ? 42.19466 54.37638 98.70393  1.000 39.73672 ? 179 TYR C CE1 1 
ATOM   4727 C CE2 . TYR C 1 180 ? 43.42556 52.37091 99.06849  1.000 36.01035 ? 179 TYR C CE2 1 
ATOM   4728 C CZ  . TYR C 1 180 ? 42.41256 53.04724 98.44457  1.000 38.38544 ? 179 TYR C CZ  1 
ATOM   4729 O OH  . TYR C 1 180 ? 41.60647 52.39952 97.55065  1.000 46.12767 ? 179 TYR C OH  1 
ATOM   4730 N N   . LYS C 1 181 ? 46.43829 55.39292 103.77519 1.000 29.68953 ? 180 LYS C N   1 
ATOM   4731 C CA  . LYS C 1 181 ? 47.46976 56.07619 104.53868 1.000 28.15451 ? 180 LYS C CA  1 
ATOM   4732 C C   . LYS C 1 181 ? 48.60155 56.46485 103.58368 1.000 33.57204 ? 180 LYS C C   1 
ATOM   4733 O O   . LYS C 1 181 ? 49.79219 56.34618 103.89384 1.000 35.07455 ? 180 LYS C O   1 
ATOM   4734 C CB  . LYS C 1 181 ? 47.92992 55.20311 105.71986 1.000 34.67564 ? 180 LYS C CB  1 
ATOM   4735 C CG  . LYS C 1 181 ? 48.74286 55.96990 106.75763 1.000 42.49729 ? 180 LYS C CG  1 
ATOM   4736 C CD  . LYS C 1 181 ? 49.09634 55.19744 108.01814 1.000 45.29490 ? 180 LYS C CD  1 
ATOM   4737 C CE  . LYS C 1 181 ? 49.93486 56.06186 108.96275 1.000 44.25236 ? 180 LYS C CE  1 
ATOM   4738 N NZ  . LYS C 1 181 ? 51.32336 56.32105 108.39704 1.000 19.62901 ? 180 LYS C NZ  1 
ATOM   4739 N N   . TYR C 1 182 ? 48.22617 56.92616 102.38078 1.000 33.81793 ? 181 TYR C N   1 
ATOM   4740 C CA  . TYR C 1 182 ? 49.18137 57.39153 101.37338 1.000 33.21105 ? 181 TYR C CA  1 
ATOM   4741 C C   . TYR C 1 182 ? 48.74325 58.79429 100.95307 1.000 34.48924 ? 181 TYR C C   1 
ATOM   4742 O O   . TYR C 1 182 ? 48.13398 59.01052 99.90263  1.000 31.68162 ? 181 TYR C O   1 
ATOM   4743 C CB  . TYR C 1 182 ? 49.30002 56.44866 100.15337 1.000 27.07543 ? 181 TYR C CB  1 
ATOM   4744 C CG  . TYR C 1 182 ? 49.21459 54.98037 100.42868 1.000 31.15587 ? 181 TYR C CG  1 
ATOM   4745 C CD1 . TYR C 1 182 ? 50.29033 54.29061 100.95467 1.000 36.05974 ? 181 TYR C CD1 1 
ATOM   4746 C CD2 . TYR C 1 182 ? 48.07000 54.26783 100.12496 1.000 31.66631 ? 181 TYR C CD2 1 
ATOM   4747 C CE1 . TYR C 1 182 ? 50.21362 52.92673 101.20297 1.000 35.18628 ? 181 TYR C CE1 1 
ATOM   4748 C CE2 . TYR C 1 182 ? 47.98884 52.91188 100.36655 1.000 31.44314 ? 181 TYR C CE2 1 
ATOM   4749 C CZ  . TYR C 1 182 ? 49.06093 52.25297 100.90741 1.000 27.41735 ? 181 TYR C CZ  1 
ATOM   4750 O OH  . TYR C 1 182 ? 48.98874 50.90656 101.14612 1.000 47.68292 ? 181 TYR C OH  1 
ATOM   4751 N N   . VAL C 1 183 ? 49.04022 59.76909 101.79153 1.000 30.85336 ? 182 VAL C N   1 
ATOM   4752 C CA  . VAL C 1 183 ? 48.82106 61.16234 101.44933 1.000 26.53857 ? 182 VAL C CA  1 
ATOM   4753 C C   . VAL C 1 183 ? 50.18923 61.82747 101.37115 1.000 23.70778 ? 182 VAL C C   1 
ATOM   4754 O O   . VAL C 1 183 ? 51.02304 61.64729 102.26308 1.000 24.16154 ? 182 VAL C O   1 
ATOM   4755 C CB  . VAL C 1 183 ? 47.87628 61.83539 102.46160 1.000 29.82451 ? 182 VAL C CB  1 
ATOM   4756 C CG1 . VAL C 1 183 ? 47.88839 63.36695 102.31905 1.000 27.49020 ? 182 VAL C CG1 1 
ATOM   4757 C CG2 . VAL C 1 183 ? 46.46442 61.29524 102.28102 1.000 25.07752 ? 182 VAL C CG2 1 
ATOM   4758 N N   . SER C 1 184 ? 50.46205 62.48880 100.25194 1.000 21.70417 ? 183 SER C N   1 
ATOM   4759 C CA  . SER C 1 184 ? 51.69702 63.22912 100.04867 1.000 21.60986 ? 183 SER C CA  1 
ATOM   4760 C C   . SER C 1 184 ? 51.40390 64.71768 99.94146  1.000 19.56086 ? 183 SER C C   1 
ATOM   4761 O O   . SER C 1 184 ? 50.26639 65.12954 99.73707  1.000 19.46408 ? 183 SER C O   1 
ATOM   4762 C CB  . SER C 1 184 ? 52.43475 62.74603 98.79556  1.000 24.25603 ? 183 SER C CB  1 
ATOM   4763 O OG  . SER C 1 184 ? 53.02248 61.46834 98.99797  1.000 26.38881 ? 183 SER C OG  1 
ATOM   4764 N N   . TRP C 1 185 ? 52.43760 65.52785 100.13118 1.000 19.85216 ? 184 TRP C N   1 
ATOM   4765 C CA  . TRP C 1 185 ? 52.36397 66.96185 99.88248  1.000 19.76843 ? 184 TRP C CA  1 
ATOM   4766 C C   . TRP C 1 185 ? 53.56788 67.38510 99.05737  1.000 22.00735 ? 184 TRP C C   1 
ATOM   4767 O O   . TRP C 1 185 ? 54.69802 67.03144 99.39793  1.000 22.17455 ? 184 TRP C O   1 
ATOM   4768 C CB  . TRP C 1 185 ? 52.31793 67.75131 101.18940 1.000 21.31397 ? 184 TRP C CB  1 
ATOM   4769 C CG  . TRP C 1 185 ? 51.06222 67.54080 101.97341 1.000 22.65718 ? 184 TRP C CG  1 
ATOM   4770 C CD1 . TRP C 1 185 ? 50.73883 66.45321 102.73713 1.000 26.54497 ? 184 TRP C CD1 1 
ATOM   4771 C CD2 . TRP C 1 185 ? 49.96043 68.44286 102.07904 1.000 26.92049 ? 184 TRP C CD2 1 
ATOM   4772 N NE1 . TRP C 1 185 ? 49.50375 66.62320 103.31618 1.000 24.82752 ? 184 TRP C NE1 1 
ATOM   4773 C CE2 . TRP C 1 185 ? 48.99995 67.83466 102.92228 1.000 27.15829 ? 184 TRP C CE2 1 
ATOM   4774 C CE3 . TRP C 1 185 ? 49.69302 69.71371 101.55221 1.000 24.92810 ? 184 TRP C CE3 1 
ATOM   4775 C CZ2 . TRP C 1 185 ? 47.79623 68.44981 103.24610 1.000 27.20939 ? 184 TRP C CZ2 1 
ATOM   4776 C CZ3 . TRP C 1 185 ? 48.49551 70.31721 101.86703 1.000 29.36650 ? 184 TRP C CZ3 1 
ATOM   4777 C CH2 . TRP C 1 185 ? 47.55675 69.68217 102.71077 1.000 32.22059 ? 184 TRP C CH2 1 
ATOM   4778 N N   . TYR C 1 186 ? 53.33010 68.13821 97.98015  1.000 23.65810 ? 185 TYR C N   1 
ATOM   4779 C CA  . TYR C 1 186 ? 54.38828 68.68016 97.13807  1.000 21.54294 ? 185 TYR C CA  1 
ATOM   4780 C C   . TYR C 1 186 ? 54.48593 70.19452 97.28338  1.000 22.96201 ? 185 TYR C C   1 
ATOM   4781 O O   . TYR C 1 186 ? 53.48463 70.89976 97.45297  1.000 23.42774 ? 185 TYR C O   1 
ATOM   4782 C CB  . TYR C 1 186 ? 54.16409 68.32451 95.65466  1.000 24.65248 ? 185 TYR C CB  1 
ATOM   4783 C CG  . TYR C 1 186 ? 54.09567 66.84122 95.39146  1.000 24.84360 ? 185 TYR C CG  1 
ATOM   4784 C CD1 . TYR C 1 186 ? 52.88693 66.15808 95.47412  1.000 24.89075 ? 185 TYR C CD1 1 
ATOM   4785 C CD2 . TYR C 1 186 ? 55.24192 66.10916 95.10329  1.000 26.48148 ? 185 TYR C CD2 1 
ATOM   4786 C CE1 . TYR C 1 186 ? 52.80972 64.77215 95.26551  1.000 24.91948 ? 185 TYR C CE1 1 
ATOM   4787 C CE2 . TYR C 1 186 ? 55.17987 64.71866 94.89392  1.000 29.04963 ? 185 TYR C CE2 1 
ATOM   4788 C CZ  . TYR C 1 186 ? 53.95757 64.06418 94.97743  1.000 30.14489 ? 185 TYR C CZ  1 
ATOM   4789 O OH  . TYR C 1 186 ? 53.87869 62.70661 94.77239  1.000 29.22393 ? 185 TYR C OH  1 
ATOM   4790 N N   . GLN C 1 187 ? 55.70669 70.69145 97.17094  1.000 26.12048 ? 186 GLN C N   1 
ATOM   4791 C CA  . GLN C 1 187 ? 55.98650 72.11749 97.12494  1.000 24.36023 ? 186 GLN C CA  1 
ATOM   4792 C C   . GLN C 1 187 ? 56.41980 72.44859 95.70822  1.000 27.94367 ? 186 GLN C C   1 
ATOM   4793 O O   . GLN C 1 187 ? 57.30583 71.77850 95.17008  1.000 32.85582 ? 186 GLN C O   1 
ATOM   4794 C CB  . GLN C 1 187 ? 57.07774 72.45770 98.13925  1.000 23.70750 ? 186 GLN C CB  1 
ATOM   4795 C CG  . GLN C 1 187 ? 57.86857 73.70003 97.88004  1.000 26.22241 ? 186 GLN C CG  1 
ATOM   4796 C CD  . GLN C 1 187 ? 58.81046 74.00844 99.03272  1.000 33.09590 ? 186 GLN C CD  1 
ATOM   4797 O OE1 . GLN C 1 187 ? 58.44781 74.73280 99.96243  1.000 32.25047 ? 186 GLN C OE1 1 
ATOM   4798 N NE2 . GLN C 1 187 ? 60.02485 73.45870 98.98095  1.000 28.30924 ? 186 GLN C NE2 1 
ATOM   4799 N N   . HIS C 1 188 ? 55.79657 73.46016 95.08895  1.000 29.27871 ? 187 HIS C N   1 
ATOM   4800 C CA  . HIS C 1 188 ? 56.07257 73.76446 93.68455  1.000 25.88085 ? 187 HIS C CA  1 
ATOM   4801 C C   . HIS C 1 188 ? 56.40657 75.23390 93.48739  1.000 31.54227 ? 187 HIS C C   1 
ATOM   4802 O O   . HIS C 1 188 ? 55.59925 76.10937 93.81799  1.000 31.05086 ? 187 HIS C O   1 
ATOM   4803 C CB  . HIS C 1 188 ? 54.91588 73.39060 92.76334  1.000 25.63638 ? 187 HIS C CB  1 
ATOM   4804 C CG  . HIS C 1 188 ? 55.17185 73.76890 91.33306  1.000 33.71054 ? 187 HIS C CG  1 
ATOM   4805 N ND1 . HIS C 1 188 ? 54.44094 74.73187 90.66525  1.000 34.93788 ? 187 HIS C ND1 1 
ATOM   4806 C CD2 . HIS C 1 188 ? 56.12551 73.35683 90.46530  1.000 30.32253 ? 187 HIS C CD2 1 
ATOM   4807 C CE1 . HIS C 1 188 ? 54.91272 74.87332 89.44113  1.000 28.40719 ? 187 HIS C CE1 1 
ATOM   4808 N NE2 . HIS C 1 188 ? 55.93463 74.04897 89.29500  1.000 33.23640 ? 187 HIS C NE2 1 
ATOM   4809 N N   . HIS C 1 189 ? 57.60109 75.49531 92.93879  1.000 31.49673 ? 188 HIS C N   1 
ATOM   4810 C CA  . HIS C 1 189 ? 58.06577 76.78768 92.45446  1.000 27.63829 ? 188 HIS C CA  1 
ATOM   4811 C C   . HIS C 1 189 ? 58.02776 76.83327 90.93673  1.000 36.34383 ? 188 HIS C C   1 
ATOM   4812 O O   . HIS C 1 189 ? 58.53904 75.91067 90.28443  1.000 36.05382 ? 188 HIS C O   1 
ATOM   4813 C CB  . HIS C 1 189 ? 59.49266 77.08014 92.91923  1.000 30.68139 ? 188 HIS C CB  1 
ATOM   4814 C CG  . HIS C 1 189 ? 59.60156 77.46099 94.36344  1.000 36.36343 ? 188 HIS C CG  1 
ATOM   4815 N ND1 . HIS C 1 189 ? 60.38891 76.77171 95.25977  1.000 37.66836 ? 188 HIS C ND1 1 
ATOM   4816 C CD2 . HIS C 1 189 ? 59.00470 78.44785 95.07196  1.000 36.06768 ? 188 HIS C CD2 1 
ATOM   4817 C CE1 . HIS C 1 189 ? 60.28233 77.32483 96.45537  1.000 37.20400 ? 188 HIS C CE1 1 
ATOM   4818 N NE2 . HIS C 1 189 ? 59.44551 78.34229 96.36921  1.000 36.97327 ? 188 HIS C NE2 1 
ATOM   4819 N N   . PRO C 1 190 ? 57.44964 77.88198 90.35022  1.000 37.04722 ? 189 PRO C N   1 
ATOM   4820 C CA  . PRO C 1 190 ? 57.41946 78.00884 88.89219  1.000 31.70148 ? 189 PRO C CA  1 
ATOM   4821 C C   . PRO C 1 190 ? 58.81001 77.89605 88.28090  1.000 32.58665 ? 189 PRO C C   1 
ATOM   4822 O O   . PRO C 1 190 ? 59.75985 78.55242 88.71084  1.000 28.88213 ? 189 PRO C O   1 
ATOM   4823 C CB  . PRO C 1 190 ? 56.81215 79.39718 88.68077  1.000 29.02253 ? 189 PRO C CB  1 
ATOM   4824 C CG  . PRO C 1 190 ? 57.01034 80.08578 89.96258  1.000 27.13695 ? 189 PRO C CG  1 
ATOM   4825 C CD  . PRO C 1 190 ? 56.83085 79.04680 90.98982  1.000 29.60848 ? 189 PRO C CD  1 
ATOM   4826 N N   . GLY C 1 191 ? 58.94450 76.99157 87.32332  1.000 30.20862 ? 190 GLY C N   1 
ATOM   4827 C CA  . GLY C 1 191 ? 60.21104 76.80658 86.66261  1.000 31.02139 ? 190 GLY C CA  1 
ATOM   4828 C C   . GLY C 1 191 ? 61.08008 75.72312 87.26334  1.000 41.68852 ? 190 GLY C C   1 
ATOM   4829 O O   . GLY C 1 191 ? 62.16695 75.45038 86.71541  1.000 37.10713 ? 190 GLY C O   1 
ATOM   4830 N N   . LYS C 1 192 ? 60.64061 75.10438 88.37240  1.000 35.78216 ? 191 LYS C N   1 
ATOM   4831 C CA  . LYS C 1 192 ? 61.35969 74.06716 89.11252  1.000 35.83010 ? 191 LYS C CA  1 
ATOM   4832 C C   . LYS C 1 192 ? 60.50998 72.80036 89.20997  1.000 37.06986 ? 191 LYS C C   1 
ATOM   4833 O O   . LYS C 1 192 ? 59.32477 72.77776 88.85158  1.000 32.90615 ? 191 LYS C O   1 
ATOM   4834 C CB  . LYS C 1 192 ? 61.75600 74.56508 90.51172  1.000 32.63415 ? 191 LYS C CB  1 
ATOM   4835 C CG  . LYS C 1 192 ? 62.72013 75.71062 90.43981  1.000 32.61889 ? 191 LYS C CG  1 
ATOM   4836 C CD  . LYS C 1 192 ? 63.04075 76.33289 91.76960  1.000 48.49083 ? 191 LYS C CD  1 
ATOM   4837 C CE  . LYS C 1 192 ? 63.81328 77.63276 91.61619  1.000 50.75805 ? 191 LYS C CE  1 
ATOM   4838 N NZ  . LYS C 1 192 ? 63.96418 78.19403 92.98876  1.000 46.96288 ? 191 LYS C NZ  1 
ATOM   4839 N N   . ALA C 1 193 ? 61.17180 71.72953 89.62060  1.000 31.64059 ? 192 ALA C N   1 
ATOM   4840 C CA  . ALA C 1 193 ? 60.54820 70.42880 89.83656  1.000 36.42076 ? 192 ALA C CA  1 
ATOM   4841 C C   . ALA C 1 193 ? 59.75008 70.42463 91.13647  1.000 31.42007 ? 192 ALA C C   1 
ATOM   4842 O O   . ALA C 1 193 ? 60.31274 70.73109 92.19257  1.000 28.94517 ? 192 ALA C O   1 
ATOM   4843 C CB  . ALA C 1 193 ? 61.63229 69.35808 89.92062  1.000 36.15382 ? 192 ALA C CB  1 
ATOM   4844 N N   . PRO C 1 194 ? 58.47887 70.00734 91.12251  1.000 30.36401 ? 193 PRO C N   1 
ATOM   4845 C CA  . PRO C 1 194 ? 57.74930 69.90816 92.38692  1.000 25.18736 ? 193 PRO C CA  1 
ATOM   4846 C C   . PRO C 1 194 ? 58.51777 68.96850 93.29767  1.000 31.75031 ? 193 PRO C C   1 
ATOM   4847 O O   . PRO C 1 194 ? 59.16597 68.01586 92.84952  1.000 28.82097 ? 193 PRO C O   1 
ATOM   4848 C CB  . PRO C 1 194 ? 56.38022 69.33383 91.98828  1.000 25.64552 ? 193 PRO C CB  1 
ATOM   4849 C CG  . PRO C 1 194 ? 56.31267 69.37331 90.50970  1.000 27.02394 ? 193 PRO C CG  1 
ATOM   4850 C CD  . PRO C 1 194 ? 57.71215 69.46589 89.98666  1.000 29.63151 ? 193 PRO C CD  1 
ATOM   4851 N N   . LYS C 1 195 ? 58.43077 69.23653 94.59072  1.000 31.37492 ? 194 LYS C N   1 
ATOM   4852 C CA  . LYS C 1 195 ? 59.28264 68.59286 95.57470  1.000 27.94528 ? 194 LYS C CA  1 
ATOM   4853 C C   . LYS C 1 195 ? 58.38802 67.93165 96.59599  1.000 32.03939 ? 194 LYS C C   1 
ATOM   4854 O O   . LYS C 1 195 ? 57.56157 68.60654 97.22105  1.000 29.27329 ? 194 LYS C O   1 
ATOM   4855 C CB  . LYS C 1 195 ? 60.18358 69.62062 96.25648  1.000 32.06306 ? 194 LYS C CB  1 
ATOM   4856 C CG  . LYS C 1 195 ? 61.13696 69.07638 97.31499  1.000 37.81901 ? 194 LYS C CG  1 
ATOM   4857 C CD  . LYS C 1 195 ? 62.18443 70.14058 97.66509  1.000 41.29421 ? 194 LYS C CD  1 
ATOM   4858 C CE  . LYS C 1 195 ? 63.01528 69.80335 98.89011  1.000 41.61782 ? 194 LYS C CE  1 
ATOM   4859 N NZ  . LYS C 1 195 ? 63.47402 68.40050 98.90745  1.000 39.84232 ? 194 LYS C NZ  1 
ATOM   4860 N N   . LEU C 1 196 ? 58.57621 66.61938 96.77629  1.000 34.69499 ? 195 LEU C N   1 
ATOM   4861 C CA  . LEU C 1 196 ? 57.84590 65.86710 97.78694  1.000 23.14070 ? 195 LEU C CA  1 
ATOM   4862 C C   . LEU C 1 196 ? 58.33595 66.29568 99.17476  1.000 24.85733 ? 195 LEU C C   1 
ATOM   4863 O O   . LEU C 1 196 ? 59.50932 66.11605 99.51177  1.000 30.35271 ? 195 LEU C O   1 
ATOM   4864 C CB  . LEU C 1 196 ? 58.04500 64.37799 97.52841  1.000 21.72086 ? 195 LEU C CB  1 
ATOM   4865 C CG  . LEU C 1 196 ? 57.38930 63.28765 98.37729  1.000 24.41351 ? 195 LEU C CG  1 
ATOM   4866 C CD1 . LEU C 1 196 ? 55.88673 63.22931 98.21128  1.000 20.83038 ? 195 LEU C CD1 1 
ATOM   4867 C CD2 . LEU C 1 196 ? 58.00195 61.97919 98.00495  1.000 26.04906 ? 195 LEU C CD2 1 
ATOM   4868 N N   . MET C 1 197 ? 57.44027 66.86176 99.97833  1.000 25.18868 ? 196 MET C N   1 
ATOM   4869 C CA  . MET C 1 197 ? 57.74727 67.31885 101.32653 1.000 28.88370 ? 196 MET C CA  1 
ATOM   4870 C C   . MET C 1 197 ? 57.32812 66.32836 102.39699 1.000 31.39080 ? 196 MET C C   1 
ATOM   4871 O O   . MET C 1 197 ? 58.07115 66.10696 103.35972 1.000 33.38439 ? 196 MET C O   1 
ATOM   4872 C CB  . MET C 1 197 ? 57.06589 68.66307 101.58933 1.000 24.32450 ? 196 MET C CB  1 
ATOM   4873 C CG  . MET C 1 197 ? 57.34944 69.69003 100.53934 1.000 22.46337 ? 196 MET C CG  1 
ATOM   4874 S SD  . MET C 1 197 ? 59.11665 69.91222 100.25591 1.000 38.96925 ? 196 MET C SD  1 
ATOM   4875 C CE  . MET C 1 197 ? 59.59429 71.07821 101.53442 1.000 31.58779 ? 196 MET C CE  1 
ATOM   4876 N N   . ILE C 1 198 ? 56.15743 65.72670 102.23480 1.000 28.32346 ? 197 ILE C N   1 
ATOM   4877 C CA  . ILE C 1 198 ? 55.61091 64.74732 103.16413 1.000 27.10924 ? 197 ILE C CA  1 
ATOM   4878 C C   . ILE C 1 198 ? 55.04372 63.59844 102.34335 1.000 28.20565 ? 197 ILE C C   1 
ATOM   4879 O O   . ILE C 1 198 ? 54.42717 63.80531 101.29289 1.000 27.95277 ? 197 ILE C O   1 
ATOM   4880 C CB  . ILE C 1 198 ? 54.52265 65.35889 104.07157 1.000 26.78186 ? 197 ILE C CB  1 
ATOM   4881 C CG1 . ILE C 1 198 ? 55.08568 66.54079 104.86007 1.000 27.46948 ? 197 ILE C CG1 1 
ATOM   4882 C CG2 . ILE C 1 198 ? 53.95207 64.32300 105.00426 1.000 29.51427 ? 197 ILE C CG2 1 
ATOM   4883 C CD1 . ILE C 1 198 ? 55.96027 66.11908 106.01270 1.000 28.49689 ? 197 ILE C CD1 1 
ATOM   4884 N N   . TYR C 1 199 ? 55.26170 62.38089 102.80839 1.000 29.21667 ? 198 TYR C N   1 
ATOM   4885 C CA  . TYR C 1 199 ? 54.67472 61.23450 102.14747 1.000 25.98863 ? 198 TYR C CA  1 
ATOM   4886 C C   . TYR C 1 199 ? 54.16427 60.27064 103.20831 1.000 30.04600 ? 198 TYR C C   1 
ATOM   4887 O O   . TYR C 1 199 ? 54.54130 60.34516 104.37875 1.000 31.36436 ? 198 TYR C O   1 
ATOM   4888 C CB  . TYR C 1 199 ? 55.67617 60.56439 101.20407 1.000 24.41838 ? 198 TYR C CB  1 
ATOM   4889 C CG  . TYR C 1 199 ? 56.71614 59.72966 101.89424 1.000 26.94908 ? 198 TYR C CG  1 
ATOM   4890 C CD1 . TYR C 1 199 ? 57.91550 60.28881 102.30267 1.000 27.43709 ? 198 TYR C CD1 1 
ATOM   4891 C CD2 . TYR C 1 199 ? 56.49723 58.36577 102.13220 1.000 26.55007 ? 198 TYR C CD2 1 
ATOM   4892 C CE1 . TYR C 1 199 ? 58.87759 59.52301 102.93370 1.000 30.78142 ? 198 TYR C CE1 1 
ATOM   4893 C CE2 . TYR C 1 199 ? 57.43660 57.59580 102.75319 1.000 29.89067 ? 198 TYR C CE2 1 
ATOM   4894 C CZ  . TYR C 1 199 ? 58.63275 58.17548 103.15516 1.000 37.08738 ? 198 TYR C CZ  1 
ATOM   4895 O OH  . TYR C 1 199 ? 59.57675 57.39635 103.78783 1.000 41.33174 ? 198 TYR C OH  1 
ATOM   4896 N N   . GLU C 1 200 ? 53.30297 59.35717 102.77892 1.000 27.98789 ? 199 GLU C N   1 
ATOM   4897 C CA  . GLU C 1 200 ? 52.64914 58.42222 103.67835 1.000 29.03629 ? 199 GLU C CA  1 
ATOM   4898 C C   . GLU C 1 200 ? 52.05569 59.16065 104.87631 1.000 27.87754 ? 199 GLU C C   1 
ATOM   4899 O O   . GLU C 1 200 ? 52.27633 58.80645 106.03257 1.000 33.37860 ? 199 GLU C O   1 
ATOM   4900 C CB  . GLU C 1 200 ? 53.62820 57.33242 104.11383 1.000 29.25745 ? 199 GLU C CB  1 
ATOM   4901 C CG  . GLU C 1 200 ? 53.58316 56.05595 103.27397 1.000 26.34448 ? 199 GLU C CG  1 
ATOM   4902 C CD  . GLU C 1 200 ? 54.79129 55.16214 103.50249 1.000 31.18401 ? 199 GLU C CD  1 
ATOM   4903 O OE1 . GLU C 1 200 ? 55.20153 54.97032 104.67351 1.000 25.81412 ? 199 GLU C OE1 1 
ATOM   4904 O OE2 . GLU C 1 200 ? 55.33754 54.65056 102.50197 1.000 33.92586 ? 199 GLU C OE2 1 
ATOM   4905 N N   . VAL C 1 201 ? 51.30352 60.21833 104.57006 1.000 28.39053 ? 200 VAL C N   1 
ATOM   4906 C CA  . VAL C 1 201 ? 50.56345 61.05622 105.51608 1.000 29.62426 ? 200 VAL C CA  1 
ATOM   4907 C C   . VAL C 1 201 ? 51.46901 61.96366 106.34578 1.000 30.23439 ? 200 VAL C C   1 
ATOM   4908 O O   . VAL C 1 201 ? 51.23046 63.17410 106.42232 1.000 27.97519 ? 200 VAL C O   1 
ATOM   4909 C CB  . VAL C 1 201 ? 49.66183 60.22439 106.43632 1.000 27.39528 ? 200 VAL C CB  1 
ATOM   4910 C CG1 . VAL C 1 201 ? 48.77844 61.16034 107.23440 1.000 30.00894 ? 200 VAL C CG1 1 
ATOM   4911 C CG2 . VAL C 1 201 ? 48.81333 59.29929 105.61674 1.000 28.47073 ? 200 VAL C CG2 1 
ATOM   4912 N N   . SER C 1 202 ? 52.49586 61.39814 106.99549 1.000 27.38715 ? 201 SER C N   1 
ATOM   4913 C CA  . SER C 1 202 ? 53.29238 62.18758 107.92602 1.000 23.57656 ? 201 SER C CA  1 
ATOM   4914 C C   . SER C 1 202 ? 54.79465 61.98435 107.78624 1.000 27.62720 ? 201 SER C C   1 
ATOM   4915 O O   . SER C 1 202 ? 55.55099 62.55043 108.58857 1.000 31.56735 ? 201 SER C O   1 
ATOM   4916 C CB  . SER C 1 202 ? 52.90403 61.87680 109.37062 1.000 26.82092 ? 201 SER C CB  1 
ATOM   4917 O OG  . SER C 1 202 ? 52.86095 60.48122 109.61649 1.000 27.77523 ? 201 SER C OG  1 
ATOM   4918 N N   . LYS C 1 203 ? 55.25895 61.20979 106.80825 1.000 28.41316 ? 202 LYS C N   1 
ATOM   4919 C CA  . LYS C 1 203 ? 56.67720 60.89199 106.69455 1.000 28.80067 ? 202 LYS C CA  1 
ATOM   4920 C C   . LYS C 1 203 ? 57.37334 61.90729 105.79811 1.000 28.54087 ? 202 LYS C C   1 
ATOM   4921 O O   . LYS C 1 203 ? 56.83462 62.29010 104.75742 1.000 31.60989 ? 202 LYS C O   1 
ATOM   4922 C CB  . LYS C 1 203 ? 56.86028 59.47430 106.13253 1.000 34.65435 ? 202 LYS C CB  1 
ATOM   4923 C CG  . LYS C 1 203 ? 56.23422 58.35403 107.00061 1.000 33.37585 ? 202 LYS C CG  1 
ATOM   4924 C CD  . LYS C 1 203 ? 56.94508 57.01577 106.82720 1.000 29.29507 ? 202 LYS C CD  1 
ATOM   4925 C CE  . LYS C 1 203 ? 56.45233 55.98908 107.84577 1.000 36.82361 ? 202 LYS C CE  1 
ATOM   4926 N NZ  . LYS C 1 203 ? 56.56087 54.57915 107.36165 1.000 42.57849 ? 202 LYS C NZ  1 
ATOM   4927 N N   . ARG C 1 204 ? 58.56830 62.36999 106.21876 1.000 25.60860 ? 203 ARG C N   1 
ATOM   4928 C CA  . ARG C 1 204 ? 59.36068 63.26686 105.37169 1.000 33.05853 ? 203 ARG C CA  1 
ATOM   4929 C C   . ARG C 1 204 ? 60.61425 62.59593 104.81777 1.000 33.49744 ? 203 ARG C C   1 
ATOM   4930 O O   . ARG C 1 204 ? 61.43142 62.05500 105.57784 1.000 34.06795 ? 203 ARG C O   1 
ATOM   4931 C CB  . ARG C 1 204 ? 59.72993 64.56413 106.11533 1.000 32.98398 ? 203 ARG C CB  1 
ATOM   4932 C CG  . ARG C 1 204 ? 60.11985 64.37631 107.53074 1.000 40.41735 ? 203 ARG C CG  1 
ATOM   4933 C CD  . ARG C 1 204 ? 60.28198 65.69601 108.22659 1.000 41.30451 ? 203 ARG C CD  1 
ATOM   4934 N NE  . ARG C 1 204 ? 60.51873 65.49014 109.64965 1.000 45.59597 ? 203 ARG C NE  1 
ATOM   4935 C CZ  . ARG C 1 204 ? 61.69925 65.13706 110.15450 1.000 47.88030 ? 203 ARG C CZ  1 
ATOM   4936 N NH1 . ARG C 1 204 ? 61.84243 64.97418 111.46546 1.000 46.27915 ? 203 ARG C NH1 1 
ATOM   4937 N NH2 . ARG C 1 204 ? 62.73712 64.93351 109.34114 1.000 45.67751 ? 203 ARG C NH2 1 
ATOM   4938 N N   . PRO C 1 205 ? 60.81015 62.64948 103.50338 1.000 35.11056 ? 204 PRO C N   1 
ATOM   4939 C CA  . PRO C 1 205 ? 62.02797 62.09662 102.89269 1.000 37.13101 ? 204 PRO C CA  1 
ATOM   4940 C C   . PRO C 1 205 ? 63.30189 62.77294 103.38099 1.000 32.28251 ? 204 PRO C C   1 
ATOM   4941 O O   . PRO C 1 205 ? 63.28482 63.84828 103.98008 1.000 38.48180 ? 204 PRO C O   1 
ATOM   4942 C CB  . PRO C 1 205 ? 61.81071 62.35763 101.39854 1.000 44.19332 ? 204 PRO C CB  1 
ATOM   4943 C CG  . PRO C 1 205 ? 60.79384 63.47327 101.34681 1.000 31.24930 ? 204 PRO C CG  1 
ATOM   4944 C CD  . PRO C 1 205 ? 59.89110 63.21600 102.50336 1.000 33.51205 ? 204 PRO C CD  1 
ATOM   4945 N N   . SER C 1 206 ? 64.43531 62.15042 103.03499 1.000 34.76644 ? 205 SER C N   1 
ATOM   4946 C CA  . SER C 1 206 ? 65.74261 62.58998 103.52690 1.000 35.19965 ? 205 SER C CA  1 
ATOM   4947 C C   . SER C 1 206 ? 66.03772 63.99379 103.05135 1.000 35.26935 ? 205 SER C C   1 
ATOM   4948 O O   . SER C 1 206 ? 66.06610 64.24929 101.84094 1.000 32.23623 ? 205 SER C O   1 
ATOM   4949 C CB  . SER C 1 206 ? 66.86719 61.65574 103.06379 1.000 36.75733 ? 205 SER C CB  1 
ATOM   4950 O OG  . SER C 1 206 ? 67.12956 61.80493 101.68037 1.000 46.13037 ? 205 SER C OG  1 
ATOM   4951 N N   . GLY C 1 207 ? 66.28683 64.88968 104.00202 1.000 38.93627 ? 206 GLY C N   1 
ATOM   4952 C CA  . GLY C 1 207 ? 66.60997 66.26124 103.67528 1.000 37.19060 ? 206 GLY C CA  1 
ATOM   4953 C C   . GLY C 1 207 ? 65.42123 67.17061 103.49491 1.000 32.27639 ? 206 GLY C C   1 
ATOM   4954 O O   . GLY C 1 207 ? 65.57093 68.25724 102.93243 1.000 35.66168 ? 206 GLY C O   1 
ATOM   4955 N N   . VAL C 1 208 ? 64.23839 66.77048 103.94888 1.000 32.34123 ? 207 VAL C N   1 
ATOM   4956 C CA  . VAL C 1 208 ? 63.10916 67.67351 104.07582 1.000 38.34561 ? 207 VAL C CA  1 
ATOM   4957 C C   . VAL C 1 208 ? 63.17329 68.25440 105.47988 1.000 40.83654 ? 207 VAL C C   1 
ATOM   4958 O O   . VAL C 1 208 ? 63.19357 67.48086 106.45337 1.000 39.02865 ? 207 VAL C O   1 
ATOM   4959 C CB  . VAL C 1 208 ? 61.76803 66.97180 103.82310 1.000 37.33100 ? 207 VAL C CB  1 
ATOM   4960 C CG1 . VAL C 1 208 ? 60.60991 67.91118 104.11274 1.000 32.74641 ? 207 VAL C CG1 1 
ATOM   4961 C CG2 . VAL C 1 208 ? 61.68573 66.54379 102.38651 1.000 36.65563 ? 207 VAL C CG2 1 
ATOM   4962 N N   . PRO C 1 209 ? 63.23299 69.57549 105.63493 1.000 36.89337 ? 208 PRO C N   1 
ATOM   4963 C CA  . PRO C 1 209 ? 63.46598 70.14116 106.95775 1.000 26.97978 ? 208 PRO C CA  1 
ATOM   4964 C C   . PRO C 1 209 ? 62.34535 69.75940 107.89821 1.000 29.60621 ? 208 PRO C C   1 
ATOM   4965 O O   . PRO C 1 209 ? 61.16684 69.92238 107.59674 1.000 33.07318 ? 208 PRO C O   1 
ATOM   4966 C CB  . PRO C 1 209 ? 63.52899 71.64826 106.71319 1.000 36.59963 ? 208 PRO C CB  1 
ATOM   4967 C CG  . PRO C 1 209 ? 63.09524 71.87413 105.31472 1.000 38.72887 ? 208 PRO C CG  1 
ATOM   4968 C CD  . PRO C 1 209 ? 62.89681 70.58749 104.61797 1.000 33.03452 ? 208 PRO C CD  1 
ATOM   4969 N N   . ASP C 1 210 ? 62.75376 69.29939 109.06465 1.000 34.50794 ? 209 ASP C N   1 
ATOM   4970 C CA  . ASP C 1 210 ? 61.97317 68.78426 110.18100 1.000 41.44113 ? 209 ASP C CA  1 
ATOM   4971 C C   . ASP C 1 210 ? 60.85746 69.69177 110.69217 1.000 38.97591 ? 209 ASP C C   1 
ATOM   4972 O O   . ASP C 1 210 ? 60.01986 69.27470 111.49562 1.000 40.24891 ? 209 ASP C O   1 
ATOM   4973 C CB  . ASP C 1 210 ? 63.03635 68.47178 111.24339 1.000 51.22557 ? 209 ASP C CB  1 
ATOM   4974 C CG  . ASP C 1 210 ? 62.48823 68.14207 112.59357 1.000 51.76214 ? 209 ASP C CG  1 
ATOM   4975 O OD1 . ASP C 1 210 ? 61.86622 67.08292 112.85311 1.000 56.17582 ? 209 ASP C OD1 1 
ATOM   4976 O OD2 . ASP C 1 210 ? 62.82465 68.96627 113.43854 1.000 43.43680 ? 209 ASP C OD2 1 
ATOM   4977 N N   . ARG C 1 211 ? 60.81023 70.91750 110.19516 1.000 36.76903 ? 210 ARG C N   1 
ATOM   4978 C CA  . ARG C 1 211 ? 59.72387 71.84666 110.47619 1.000 40.03994 ? 210 ARG C CA  1 
ATOM   4979 C C   . ARG C 1 211 ? 58.49595 71.65577 109.58578 1.000 43.17207 ? 210 ARG C C   1 
ATOM   4980 O O   . ARG C 1 211 ? 57.48228 72.32857 109.81779 1.000 44.86790 ? 210 ARG C O   1 
ATOM   4981 C CB  . ARG C 1 211 ? 60.23675 73.26919 110.34622 1.000 38.47060 ? 210 ARG C CB  1 
ATOM   4982 C CG  . ARG C 1 211 ? 60.66411 73.59828 108.96746 1.000 27.58985 ? 210 ARG C CG  1 
ATOM   4983 C CD  . ARG C 1 211 ? 61.77866 74.57995 109.03654 1.000 31.27359 ? 210 ARG C CD  1 
ATOM   4984 N NE  . ARG C 1 211 ? 62.12292 75.09279 107.72725 1.000 30.82954 ? 210 ARG C NE  1 
ATOM   4985 C CZ  . ARG C 1 211 ? 61.38104 75.98960 107.10198 1.000 34.28033 ? 210 ARG C CZ  1 
ATOM   4986 N NH1 . ARG C 1 211 ? 60.28342 76.43034 107.69426 1.000 38.81558 ? 210 ARG C NH1 1 
ATOM   4987 N NH2 . ARG C 1 211 ? 61.72390 76.45176 105.90788 1.000 36.83332 ? 210 ARG C NH2 1 
ATOM   4988 N N   . PHE C 1 212 ? 58.57031 70.79990 108.56103 1.000 39.71000 ? 211 PHE C N   1 
ATOM   4989 C CA  . PHE C 1 212 ? 57.41038 70.41719 107.75702 1.000 34.81449 ? 211 PHE C CA  1 
ATOM   4990 C C   . PHE C 1 212 ? 56.71546 69.22270 108.40738 1.000 32.99944 ? 211 PHE C C   1 
ATOM   4991 O O   . PHE C 1 212 ? 57.35853 68.21300 108.71428 1.000 38.68063 ? 211 PHE C O   1 
ATOM   4992 C CB  . PHE C 1 212 ? 57.83773 70.09293 106.32476 1.000 33.38017 ? 211 PHE C CB  1 
ATOM   4993 C CG  . PHE C 1 212 ? 58.13787 71.31152 105.49254 1.000 30.54944 ? 211 PHE C CG  1 
ATOM   4994 C CD1 . PHE C 1 212 ? 57.14422 71.91505 104.74157 1.000 31.55943 ? 211 PHE C CD1 1 
ATOM   4995 C CD2 . PHE C 1 212 ? 59.40972 71.85455 105.46784 1.000 28.63154 ? 211 PHE C CD2 1 
ATOM   4996 C CE1 . PHE C 1 212 ? 57.42071 73.03823 103.97866 1.000 35.75497 ? 211 PHE C CE1 1 
ATOM   4997 C CE2 . PHE C 1 212 ? 59.68936 72.98339 104.71855 1.000 31.47402 ? 211 PHE C CE2 1 
ATOM   4998 C CZ  . PHE C 1 212 ? 58.69920 73.57224 103.96759 1.000 33.42508 ? 211 PHE C CZ  1 
ATOM   4999 N N   . SER C 1 213 ? 55.39818 69.33381 108.59382 1.000 32.24550 ? 212 SER C N   1 
ATOM   5000 C CA  . SER C 1 213 ? 54.64258 68.43440 109.45826 1.000 32.18678 ? 212 SER C CA  1 
ATOM   5001 C C   . SER C 1 213 ? 53.45148 67.85861 108.70520 1.000 36.10572 ? 212 SER C C   1 
ATOM   5002 O O   . SER C 1 213 ? 52.72453 68.60431 108.03679 1.000 31.54077 ? 212 SER C O   1 
ATOM   5003 C CB  . SER C 1 213 ? 54.13693 69.21595 110.68425 1.000 38.40068 ? 212 SER C CB  1 
ATOM   5004 O OG  . SER C 1 213 ? 55.12261 70.12243 111.20302 1.000 37.95160 ? 212 SER C OG  1 
ATOM   5005 N N   . GLY C 1 214 ? 53.24663 66.54858 108.82161 1.000 29.20073 ? 213 GLY C N   1 
ATOM   5006 C CA  . GLY C 1 214 ? 52.12913 65.87309 108.17392 1.000 24.74017 ? 213 GLY C CA  1 
ATOM   5007 C C   . GLY C 1 214 ? 51.23347 65.13486 109.15019 1.000 29.74604 ? 213 GLY C C   1 
ATOM   5008 O O   . GLY C 1 214 ? 51.71324 64.54424 110.12297 1.000 27.37911 ? 213 GLY C O   1 
ATOM   5009 N N   . SER C 1 215 ? 49.93236 65.12905 108.86079 1.000 27.00989 ? 214 SER C N   1 
ATOM   5010 C CA  . SER C 1 215 ? 48.94478 64.45175 109.68897 1.000 20.53526 ? 214 SER C CA  1 
ATOM   5011 C C   . SER C 1 215 ? 47.60795 64.41704 108.94980 1.000 28.17169 ? 214 SER C C   1 
ATOM   5012 O O   . SER C 1 215 ? 47.39598 65.13826 107.97096 1.000 30.91651 ? 214 SER C O   1 
ATOM   5013 C CB  . SER C 1 215 ? 48.80144 65.13239 111.04342 1.000 28.73087 ? 214 SER C CB  1 
ATOM   5014 O OG  . SER C 1 215 ? 48.05243 66.33130 110.92231 1.000 36.26786 ? 214 SER C OG  1 
ATOM   5015 N N   . LYS C 1 216 ? 46.69044 63.59688 109.46528 1.000 26.44167 ? 215 LYS C N   1 
ATOM   5016 C CA  . LYS C 1 216 ? 45.39573 63.35543 108.84591 1.000 26.46818 ? 215 LYS C CA  1 
ATOM   5017 C C   . LYS C 1 216 ? 44.40703 62.94324 109.92727 1.000 22.48520 ? 215 LYS C C   1 
ATOM   5018 O O   . LYS C 1 216 ? 44.78998 62.44852 110.97986 1.000 23.16590 ? 215 LYS C O   1 
ATOM   5019 C CB  . LYS C 1 216 ? 45.47527 62.26495 107.76652 1.000 33.31278 ? 215 LYS C CB  1 
ATOM   5020 C CG  . LYS C 1 216 ? 44.13142 61.78350 107.27333 1.000 31.24179 ? 215 LYS C CG  1 
ATOM   5021 C CD  . LYS C 1 216 ? 44.25774 60.78295 106.19350 1.000 32.43930 ? 215 LYS C CD  1 
ATOM   5022 C CE  . LYS C 1 216 ? 44.40322 59.42134 106.73828 1.000 28.91295 ? 215 LYS C CE  1 
ATOM   5023 N NZ  . LYS C 1 216 ? 44.48261 58.50771 105.58566 1.000 29.32633 ? 215 LYS C NZ  1 
ATOM   5024 N N   . SER C 1 217 ? 43.12689 63.17056 109.66042 1.000 22.79176 ? 216 SER C N   1 
ATOM   5025 C CA  . SER C 1 217 ? 42.05119 62.74822 110.54278 1.000 22.82258 ? 216 SER C CA  1 
ATOM   5026 C C   . SER C 1 217 ? 40.77077 62.73826 109.72997 1.000 25.12265 ? 216 SER C C   1 
ATOM   5027 O O   . SER C 1 217 ? 40.47067 63.71603 109.04797 1.000 28.87333 ? 216 SER C O   1 
ATOM   5028 C CB  . SER C 1 217 ? 41.91831 63.69606 111.73375 1.000 33.77989 ? 216 SER C CB  1 
ATOM   5029 O OG  . SER C 1 217 ? 41.03093 63.17644 112.70659 1.000 40.15364 ? 216 SER C OG  1 
ATOM   5030 N N   . GLY C 1 218 ? 40.04790 61.63556 109.75967 1.000 30.52875 ? 217 GLY C N   1 
ATOM   5031 C CA  . GLY C 1 218 ? 38.86723 61.55039 108.91375 1.000 30.84404 ? 217 GLY C CA  1 
ATOM   5032 C C   . GLY C 1 218 ? 39.25876 61.73243 107.46546 1.000 33.19446 ? 217 GLY C C   1 
ATOM   5033 O O   . GLY C 1 218 ? 40.23540 61.14369 106.99045 1.000 36.48040 ? 217 GLY C O   1 
ATOM   5034 N N   . ASN C 1 219 ? 38.51865 62.58287 106.75299 1.000 37.72093 ? 218 ASN C N   1 
ATOM   5035 C CA  . ASN C 1 219 ? 38.72254 62.78818 105.32168 1.000 39.98087 ? 218 ASN C CA  1 
ATOM   5036 C C   . ASN C 1 219 ? 39.62661 63.97622 105.01675 1.000 33.42197 ? 218 ASN C C   1 
ATOM   5037 O O   . ASN C 1 219 ? 39.64629 64.44685 103.87385 1.000 34.99170 ? 218 ASN C O   1 
ATOM   5038 C CB  . ASN C 1 219 ? 37.38136 62.97776 104.60747 1.000 40.31621 ? 218 ASN C CB  1 
ATOM   5039 C CG  . ASN C 1 219 ? 36.51796 61.72609 104.63738 1.000 42.10273 ? 218 ASN C CG  1 
ATOM   5040 O OD1 . ASN C 1 219 ? 36.97434 60.63177 104.29950 1.000 39.68300 ? 218 ASN C OD1 1 
ATOM   5041 N ND2 . ASN C 1 219 ? 35.25797 61.88669 105.04355 1.000 40.64532 ? 218 ASN C ND2 1 
ATOM   5042 N N   . MET C 1 220 ? 40.39003 64.45210 105.99692 1.000 24.74029 ? 219 MET C N   1 
ATOM   5043 C CA  . MET C 1 220 ? 41.05978 65.73671 105.87610 1.000 29.73059 ? 219 MET C CA  1 
ATOM   5044 C C   . MET C 1 220 ? 42.48702 65.65637 106.38822 1.000 27.39370 ? 219 MET C C   1 
ATOM   5045 O O   . MET C 1 220 ? 42.71218 65.35456 107.56162 1.000 27.37113 ? 219 MET C O   1 
ATOM   5046 C CB  . MET C 1 220 ? 40.27112 66.81053 106.64039 1.000 40.48459 ? 219 MET C CB  1 
ATOM   5047 C CG  . MET C 1 220 ? 40.82702 68.23488 106.55539 1.000 43.81252 ? 219 MET C CG  1 
ATOM   5048 S SD  . MET C 1 220 ? 40.00414 69.37275 107.70526 1.000 48.87764 ? 219 MET C SD  1 
ATOM   5049 C CE  . MET C 1 220 ? 41.42362 70.13526 108.47900 1.000 34.59037 ? 219 MET C CE  1 
ATOM   5050 N N   . ALA C 1 221 ? 43.44114 65.96551 105.51625 1.000 34.68830 ? 220 ALA C N   1 
ATOM   5051 C CA  . ALA C 1 221 ? 44.85660 66.05086 105.85475 1.000 33.01206 ? 220 ALA C CA  1 
ATOM   5052 C C   . ALA C 1 221 ? 45.24233 67.49597 106.14034 1.000 31.72162 ? 220 ALA C C   1 
ATOM   5053 O O   . ALA C 1 221 ? 44.54680 68.43868 105.74850 1.000 32.02967 ? 220 ALA C O   1 
ATOM   5054 C CB  . ALA C 1 221 ? 45.73479 65.49638 104.72826 1.000 29.34363 ? 220 ALA C CB  1 
ATOM   5055 N N   . SER C 1 222 ? 46.35739 67.65475 106.85932 1.000 32.04904 ? 221 SER C N   1 
ATOM   5056 C CA  . SER C 1 222 ? 46.87081 68.96153 107.23769 1.000 27.30369 ? 221 SER C CA  1 
ATOM   5057 C C   . SER C 1 222 ? 48.38006 68.98500 107.08701 1.000 31.08854 ? 221 SER C C   1 
ATOM   5058 O O   . SER C 1 222 ? 49.06266 68.02625 107.45186 1.000 29.43653 ? 221 SER C O   1 
ATOM   5059 C CB  . SER C 1 222 ? 46.51583 69.29912 108.68087 1.000 32.14152 ? 221 SER C CB  1 
ATOM   5060 O OG  . SER C 1 222 ? 45.11871 69.35183 108.87141 1.000 34.51806 ? 221 SER C OG  1 
ATOM   5061 N N   . LEU C 1 223 ? 48.89177 70.08503 106.55246 1.000 33.45606 ? 222 LEU C N   1 
ATOM   5062 C CA  . LEU C 1 223 ? 50.32001 70.35914 106.47639 1.000 33.33024 ? 222 LEU C CA  1 
ATOM   5063 C C   . LEU C 1 223 ? 50.64570 71.50363 107.42214 1.000 34.72797 ? 222 LEU C C   1 
ATOM   5064 O O   . LEU C 1 223 ? 49.82928 72.40255 107.60573 1.000 37.60621 ? 222 LEU C O   1 
ATOM   5065 C CB  . LEU C 1 223 ? 50.74537 70.72593 105.04560 1.000 35.73273 ? 222 LEU C CB  1 
ATOM   5066 C CG  . LEU C 1 223 ? 52.23687 70.84488 104.68786 1.000 34.33548 ? 222 LEU C CG  1 
ATOM   5067 C CD1 . LEU C 1 223 ? 53.03693 69.63399 105.14892 1.000 31.10866 ? 222 LEU C CD1 1 
ATOM   5068 C CD2 . LEU C 1 223 ? 52.43102 71.07577 103.20497 1.000 27.41240 ? 222 LEU C CD2 1 
ATOM   5069 N N   . THR C 1 224 ? 51.81802 71.45310 108.05945 1.000 36.05103 ? 223 THR C N   1 
ATOM   5070 C CA  . THR C 1 224 ? 52.25787 72.53454 108.93945 1.000 29.65517 ? 223 THR C CA  1 
ATOM   5071 C C   . THR C 1 224 ? 53.71609 72.87474 108.67999 1.000 34.01523 ? 223 THR C C   1 
ATOM   5072 O O   . THR C 1 224 ? 54.58653 72.02033 108.85524 1.000 33.15636 ? 223 THR C O   1 
ATOM   5073 C CB  . THR C 1 224 ? 52.08799 72.16566 110.40597 1.000 30.67917 ? 223 THR C CB  1 
ATOM   5074 O OG1 . THR C 1 224 ? 50.70026 72.18100 110.74890 1.000 31.37075 ? 223 THR C OG1 1 
ATOM   5075 C CG2 . THR C 1 224 ? 52.83783 73.16859 111.26795 1.000 32.81736 ? 223 THR C CG2 1 
ATOM   5076 N N   . VAL C 1 225 ? 53.99699 74.11601 108.28975 1.000 36.14320 ? 224 VAL C N   1 
ATOM   5077 C CA  . VAL C 1 225 ? 55.37258 74.59157 108.16887 1.000 35.60341 ? 224 VAL C CA  1 
ATOM   5078 C C   . VAL C 1 225 ? 55.65352 75.41232 109.42585 1.000 40.74614 ? 224 VAL C C   1 
ATOM   5079 O O   . VAL C 1 225 ? 55.23004 76.56640 109.53241 1.000 39.21811 ? 224 VAL C O   1 
ATOM   5080 C CB  . VAL C 1 225 ? 55.59043 75.42322 106.90270 1.000 32.26967 ? 224 VAL C CB  1 
ATOM   5081 C CG1 . VAL C 1 225 ? 57.05131 75.79239 106.76776 1.000 25.76227 ? 224 VAL C CG1 1 
ATOM   5082 C CG2 . VAL C 1 225 ? 55.04639 74.72002 105.67265 1.000 35.81043 ? 224 VAL C CG2 1 
ATOM   5083 N N   . SER C 1 226 ? 56.37434 74.83294 110.37995 1.000 41.03269 ? 225 SER C N   1 
ATOM   5084 C CA  . SER C 1 226 ? 56.81809 75.58393 111.54490 1.000 38.69039 ? 225 SER C CA  1 
ATOM   5085 C C   . SER C 1 226 ? 58.00940 76.45685 111.17855 1.000 38.69653 ? 225 SER C C   1 
ATOM   5086 O O   . SER C 1 226 ? 58.79487 76.12798 110.28683 1.000 44.40358 ? 225 SER C O   1 
ATOM   5087 C CB  . SER C 1 226 ? 57.19304 74.64609 112.69796 1.000 49.34757 ? 225 SER C CB  1 
ATOM   5088 O OG  . SER C 1 226 ? 56.08453 73.86378 113.13984 1.000 45.96210 ? 225 SER C OG  1 
ATOM   5089 N N   . GLY C 1 227 ? 58.12558 77.58577 111.86686 1.000 36.08658 ? 226 GLY C N   1 
ATOM   5090 C CA  . GLY C 1 227 ? 59.22711 78.50077 111.66033 1.000 35.62352 ? 226 GLY C CA  1 
ATOM   5091 C C   . GLY C 1 227 ? 59.44005 78.83492 110.20437 1.000 35.78289 ? 226 GLY C C   1 
ATOM   5092 O O   . GLY C 1 227 ? 60.47412 78.48902 109.62876 1.000 41.19840 ? 226 GLY C O   1 
ATOM   5093 N N   . LEU C 1 228 ? 58.46082 79.50103 109.60003 1.000 32.08692 ? 227 LEU C N   1 
ATOM   5094 C CA  . LEU C 1 228 ? 58.52163 79.82903 108.18532 1.000 29.65344 ? 227 LEU C CA  1 
ATOM   5095 C C   . LEU C 1 228 ? 59.82551 80.49171 107.77888 1.000 37.08408 ? 227 LEU C C   1 
ATOM   5096 O O   . LEU C 1 228 ? 60.55948 81.03531 108.60824 1.000 38.06494 ? 227 LEU C O   1 
ATOM   5097 C CB  . LEU C 1 228 ? 57.34337 80.72062 107.80429 1.000 37.74006 ? 227 LEU C CB  1 
ATOM   5098 C CG  . LEU C 1 228 ? 56.07909 80.00422 107.35558 1.000 32.26325 ? 227 LEU C CG  1 
ATOM   5099 C CD1 . LEU C 1 228 ? 54.86320 80.92707 107.47334 1.000 33.00374 ? 227 LEU C CD1 1 
ATOM   5100 C CD2 . LEU C 1 228 ? 56.28824 79.61025 105.91852 1.000 34.88029 ? 227 LEU C CD2 1 
ATOM   5101 N N   . GLN C 1 229 ? 60.07994 80.48234 106.47827 1.000 38.85747 ? 228 GLN C N   1 
ATOM   5102 C CA  . GLN C 1 229 ? 61.31174 80.96708 105.88874 1.000 33.69659 ? 228 GLN C CA  1 
ATOM   5103 C C   . GLN C 1 229 ? 60.95400 81.54038 104.53503 1.000 38.57996 ? 228 GLN C C   1 
ATOM   5104 O O   . GLN C 1 229 ? 59.88845 81.25317 103.98461 1.000 39.84273 ? 228 GLN C O   1 
ATOM   5105 C CB  . GLN C 1 229 ? 62.33947 79.84455 105.71424 1.000 45.19775 ? 228 GLN C CB  1 
ATOM   5106 C CG  . GLN C 1 229 ? 62.84609 79.20727 106.98969 1.000 44.85944 ? 228 GLN C CG  1 
ATOM   5107 C CD  . GLN C 1 229 ? 64.06741 79.91132 107.51947 1.000 58.94784 ? 228 GLN C CD  1 
ATOM   5108 O OE1 . GLN C 1 229 ? 63.97861 80.72993 108.44316 1.000 62.27103 ? 228 GLN C OE1 1 
ATOM   5109 N NE2 . GLN C 1 229 ? 65.22695 79.60929 106.92551 1.000 55.54800 ? 228 GLN C NE2 1 
ATOM   5110 N N   . ALA C 1 230 ? 61.83588 82.38776 104.01522 1.000 41.72703 ? 229 ALA C N   1 
ATOM   5111 C CA  . ALA C 1 230 ? 61.55577 82.99790 102.72613 1.000 36.56956 ? 229 ALA C CA  1 
ATOM   5112 C C   . ALA C 1 230 ? 61.39192 81.93980 101.64378 1.000 37.40987 ? 229 ALA C C   1 
ATOM   5113 O O   . ALA C 1 230 ? 60.46607 82.02308 100.82933 1.000 37.46179 ? 229 ALA C O   1 
ATOM   5114 C CB  . ALA C 1 230 ? 62.66861 83.97261 102.35642 1.000 43.59491 ? 229 ALA C CB  1 
ATOM   5115 N N   . GLU C 1 231 ? 62.24304 80.89870 101.65182 1.000 44.39103 ? 230 GLU C N   1 
ATOM   5116 C CA  . GLU C 1 231 ? 62.15561 79.91007 100.58435 1.000 35.83127 ? 230 GLU C CA  1 
ATOM   5117 C C   . GLU C 1 231 ? 60.82056 79.18206 100.60242 1.000 34.43783 ? 230 GLU C C   1 
ATOM   5118 O O   . GLU C 1 231 ? 60.47947 78.50230 99.62854  1.000 37.30365 ? 230 GLU C O   1 
ATOM   5119 C CB  . GLU C 1 231 ? 63.16008 78.76378 100.67127 1.000 33.04243 ? 230 GLU C CB  1 
ATOM   5120 C CG  . GLU C 1 231 ? 62.62476 77.72833 101.62358 1.000 41.05358 ? 230 GLU C CG  1 
ATOM   5121 C CD  . GLU C 1 231 ? 63.26879 76.36501 101.51027 1.000 56.63042 ? 230 GLU C CD  1 
ATOM   5122 O OE1 . GLU C 1 231 ? 64.29173 76.23237 100.80390 1.000 63.10537 ? 230 GLU C OE1 1 
ATOM   5123 O OE2 . GLU C 1 231 ? 62.60905 75.38837 101.95644 1.000 51.84359 ? 230 GLU C OE2 1 
ATOM   5124 N N   . ASP C 1 232 ? 60.06762 79.28086 101.68954 1.000 33.95045 ? 231 ASP C N   1 
ATOM   5125 C CA  . ASP C 1 232 ? 58.89517 78.43640 101.83241 1.000 34.96118 ? 231 ASP C CA  1 
ATOM   5126 C C   . ASP C 1 232 ? 57.71618 78.95319 101.04474 1.000 35.61897 ? 231 ASP C C   1 
ATOM   5127 O O   . ASP C 1 232 ? 56.62288 78.38146 101.12542 1.000 34.71934 ? 231 ASP C O   1 
ATOM   5128 C CB  . ASP C 1 232 ? 58.49699 78.33686 103.30056 1.000 32.53472 ? 231 ASP C CB  1 
ATOM   5129 C CG  . ASP C 1 232 ? 59.52828 77.64308 104.13048 1.000 34.03784 ? 231 ASP C CG  1 
ATOM   5130 O OD1 . ASP C 1 232 ? 60.44058 77.03498 103.54441 1.000 36.57163 ? 231 ASP C OD1 1 
ATOM   5131 O OD2 . ASP C 1 232 ? 59.42097 77.69787 105.37324 1.000 32.32898 ? 231 ASP C OD2 1 
ATOM   5132 N N   . GLU C 1 233 ? 57.90619 80.01688 100.29153 1.000 36.61540 ? 232 GLU C N   1 
ATOM   5133 C CA  . GLU C 1 233 ? 56.78745 80.64393 99.62069  1.000 36.81389 ? 232 GLU C CA  1 
ATOM   5134 C C   . GLU C 1 233 ? 56.59770 79.86409 98.32068  1.000 35.86731 ? 232 GLU C C   1 
ATOM   5135 O O   . GLU C 1 233 ? 57.48778 79.86955 97.46931  1.000 35.82259 ? 232 GLU C O   1 
ATOM   5136 C CB  . GLU C 1 233 ? 57.12205 82.10420 99.37763  1.000 32.63795 ? 232 GLU C CB  1 
ATOM   5137 C CG  . GLU C 1 233 ? 55.93623 82.97049 99.28780  1.000 42.31941 ? 232 GLU C CG  1 
ATOM   5138 C CD  . GLU C 1 233 ? 56.29061 84.37830 98.90772  1.000 48.85398 ? 232 GLU C CD  1 
ATOM   5139 O OE1 . GLU C 1 233 ? 57.39901 84.58560 98.35862  1.000 57.65163 ? 232 GLU C OE1 1 
ATOM   5140 O OE2 . GLU C 1 233 ? 55.56725 85.29885 99.35749  1.000 43.21638 ? 232 GLU C OE2 1 
ATOM   5141 N N   . ALA C 1 234 ? 55.52277 79.09180 98.20047  1.000 30.28925 ? 233 ALA C N   1 
ATOM   5142 C CA  . ALA C 1 234 ? 55.37219 78.23454 97.03115  1.000 25.95666 ? 233 ALA C CA  1 
ATOM   5143 C C   . ALA C 1 234 ? 53.91522 77.83663 96.88480  1.000 25.60908 ? 233 ALA C C   1 
ATOM   5144 O O   . ALA C 1 234 ? 53.05008 78.29192 97.63523  1.000 33.43332 ? 233 ALA C O   1 
ATOM   5145 C CB  . ALA C 1 234 ? 56.27315 77.00989 97.12586  1.000 29.26460 ? 233 ALA C CB  1 
ATOM   5146 N N   . ASP C 1 235 ? 53.63475 77.03301 95.86403  1.000 20.81875 ? 234 ASP C N   1 
ATOM   5147 C CA  . ASP C 1 235 ? 52.34737 76.35754 95.75874  1.000 25.91230 ? 234 ASP C CA  1 
ATOM   5148 C C   . ASP C 1 235 ? 52.44585 74.97050 96.40085  1.000 22.58143 ? 234 ASP C C   1 
ATOM   5149 O O   . ASP C 1 235 ? 53.40889 74.24098 96.15938  1.000 26.37649 ? 234 ASP C O   1 
ATOM   5150 C CB  . ASP C 1 235 ? 51.91840 76.27533 94.29283  1.000 28.42324 ? 234 ASP C CB  1 
ATOM   5151 C CG  . ASP C 1 235 ? 51.31477 77.59566 93.77222  1.000 29.06062 ? 234 ASP C CG  1 
ATOM   5152 O OD1 . ASP C 1 235 ? 51.71305 78.06860 92.67606  1.000 25.60259 ? 234 ASP C OD1 1 
ATOM   5153 O OD2 . ASP C 1 235 ? 50.42781 78.15346 94.45432  1.000 29.27522 ? 234 ASP C OD2 1 
ATOM   5154 N N   . TYR C 1 236 ? 51.45693 74.60667 97.21886  1.000 24.75779 ? 235 TYR C N   1 
ATOM   5155 C CA  . TYR C 1 236 ? 51.47931 73.34746 97.97214  1.000 25.59062 ? 235 TYR C CA  1 
ATOM   5156 C C   . TYR C 1 236 ? 50.28215 72.49927 97.58816  1.000 24.78449 ? 235 TYR C C   1 
ATOM   5157 O O   . TYR C 1 236 ? 49.13714 72.90332 97.80650  1.000 24.81100 ? 235 TYR C O   1 
ATOM   5158 C CB  . TYR C 1 236 ? 51.48821 73.59295 99.48837  1.000 21.22700 ? 235 TYR C CB  1 
ATOM   5159 C CG  . TYR C 1 236 ? 52.83648 74.08840 99.99680  1.000 26.17712 ? 235 TYR C CG  1 
ATOM   5160 C CD1 . TYR C 1 236 ? 53.10216 75.45390 100.14247 1.000 25.96475 ? 235 TYR C CD1 1 
ATOM   5161 C CD2 . TYR C 1 236 ? 53.86043 73.19433 100.27715 1.000 25.78094 ? 235 TYR C CD2 1 
ATOM   5162 C CE1 . TYR C 1 236 ? 54.33809 75.89969 100.58862 1.000 24.08266 ? 235 TYR C CE1 1 
ATOM   5163 C CE2 . TYR C 1 236 ? 55.09482 73.63755 100.70642 1.000 28.44243 ? 235 TYR C CE2 1 
ATOM   5164 C CZ  . TYR C 1 236 ? 55.32044 74.98393 100.86646 1.000 22.44172 ? 235 TYR C CZ  1 
ATOM   5165 O OH  . TYR C 1 236 ? 56.54417 75.38970 101.29318 1.000 21.13065 ? 235 TYR C OH  1 
ATOM   5166 N N   . TYR C 1 237 ? 50.54973 71.33455 97.00682  1.000 25.50874 ? 236 TYR C N   1 
ATOM   5167 C CA  . TYR C 1 237 ? 49.51294 70.42448 96.55037  1.000 23.12663 ? 236 TYR C CA  1 
ATOM   5168 C C   . TYR C 1 237 ? 49.47216 69.16033 97.40914  1.000 23.13725 ? 236 TYR C C   1 
ATOM   5169 O O   . TYR C 1 237 ? 50.50824 68.63176 97.82552  1.000 17.52268 ? 236 TYR C O   1 
ATOM   5170 C CB  . TYR C 1 237 ? 49.73966 70.06505 95.08223  1.000 25.61389 ? 236 TYR C CB  1 
ATOM   5171 C CG  . TYR C 1 237 ? 49.78660 71.24439 94.11687  1.000 27.44837 ? 236 TYR C CG  1 
ATOM   5172 C CD1 . TYR C 1 237 ? 50.96726 71.96607 93.91031  1.000 26.80520 ? 236 TYR C CD1 1 
ATOM   5173 C CD2 . TYR C 1 237 ? 48.65408 71.62367 93.39078  1.000 26.14014 ? 236 TYR C CD2 1 
ATOM   5174 C CE1 . TYR C 1 237 ? 51.00999 73.05245 93.01743  1.000 24.67815 ? 236 TYR C CE1 1 
ATOM   5175 C CE2 . TYR C 1 237 ? 48.69012 72.70047 92.49426  1.000 23.65531 ? 236 TYR C CE2 1 
ATOM   5176 C CZ  . TYR C 1 237 ? 49.86367 73.40516 92.30407  1.000 23.16593 ? 236 TYR C CZ  1 
ATOM   5177 O OH  . TYR C 1 237 ? 49.89247 74.45470 91.39580  1.000 22.08728 ? 236 TYR C OH  1 
ATOM   5178 N N   . CYS C 1 238 ? 48.27129 68.67096 97.66749  1.000 27.73741 ? 237 CYS C N   1 
ATOM   5179 C CA  . CYS C 1 238 ? 48.07526 67.43241 98.40335  1.000 24.86056 ? 237 CYS C CA  1 
ATOM   5180 C C   . CYS C 1 238 ? 47.58139 66.35545 97.44125  1.000 25.08400 ? 237 CYS C C   1 
ATOM   5181 O O   . CYS C 1 238 ? 47.03864 66.65873 96.37252  1.000 28.42576 ? 237 CYS C O   1 
ATOM   5182 C CB  . CYS C 1 238 ? 47.09354 67.62759 99.56847  1.000 19.72080 ? 237 CYS C CB  1 
ATOM   5183 S SG  . CYS C 1 238 ? 45.43296 68.14703 99.05908  1.000 31.96459 ? 237 CYS C SG  1 
ATOM   5184 N N   . SER C 1 239 ? 47.84824 65.09944 97.78968  1.000 22.06370 ? 238 SER C N   1 
ATOM   5185 C CA  . SER C 1 239 ? 47.47567 63.97038 96.95062  1.000 24.21711 ? 238 SER C CA  1 
ATOM   5186 C C   . SER C 1 239 ? 47.14535 62.75951 97.80938  1.000 24.51833 ? 238 SER C C   1 
ATOM   5187 O O   . SER C 1 239 ? 47.62689 62.61111 98.93750  1.000 19.72058 ? 238 SER C O   1 
ATOM   5188 C CB  . SER C 1 239 ? 48.57953 63.62264 95.92838  1.000 24.80448 ? 238 SER C CB  1 
ATOM   5189 O OG  . SER C 1 239 ? 49.86386 63.56493 96.52401  1.000 20.53999 ? 238 SER C OG  1 
ATOM   5190 N N   . SER C 1 240 ? 46.30619 61.89900 97.25365  1.000 30.29760 ? 239 SER C N   1 
ATOM   5191 C CA  . SER C 1 240 ? 45.99772 60.60732 97.84120  1.000 29.21710 ? 239 SER C CA  1 
ATOM   5192 C C   . SER C 1 240 ? 45.93496 59.55942 96.73770  1.000 30.67886 ? 239 SER C C   1 
ATOM   5193 O O   . SER C 1 240 ? 45.54727 59.85687 95.60677  1.000 30.91644 ? 239 SER C O   1 
ATOM   5194 C CB  . SER C 1 240 ? 44.66965 60.63093 98.60288  1.000 34.70391 ? 239 SER C CB  1 
ATOM   5195 O OG  . SER C 1 240 ? 44.13109 59.31464 98.70625  1.000 36.63908 ? 239 SER C OG  1 
ATOM   5196 N N   . TYR C 1 241 ? 46.38274 58.34906 97.05115  1.000 38.66546 ? 240 TYR C N   1 
ATOM   5197 C CA  . TYR C 1 241 ? 45.98452 57.19354 96.26260  1.000 34.58111 ? 240 TYR C CA  1 
ATOM   5198 C C   . TYR C 1 241 ? 44.45864 57.10699 96.27611  1.000 37.92127 ? 240 TYR C C   1 
ATOM   5199 O O   . TYR C 1 241 ? 43.81726 57.41548 97.28566  1.000 39.49287 ? 240 TYR C O   1 
ATOM   5200 C CB  . TYR C 1 241 ? 46.63925 55.93842 96.83529  1.000 28.49843 ? 240 TYR C CB  1 
ATOM   5201 C CG  . TYR C 1 241 ? 46.25104 54.64643 96.16929  1.000 35.26490 ? 240 TYR C CG  1 
ATOM   5202 C CD1 . TYR C 1 241 ? 46.51831 54.41872 94.83453  1.000 37.94385 ? 240 TYR C CD1 1 
ATOM   5203 C CD2 . TYR C 1 241 ? 45.61311 53.64869 96.88373  1.000 41.02355 ? 240 TYR C CD2 1 
ATOM   5204 C CE1 . TYR C 1 241 ? 46.15624 53.22800 94.22658  1.000 41.81981 ? 240 TYR C CE1 1 
ATOM   5205 C CE2 . TYR C 1 241 ? 45.24516 52.46235 96.28687  1.000 42.82285 ? 240 TYR C CE2 1 
ATOM   5206 C CZ  . TYR C 1 241 ? 45.51470 52.25461 94.95600  1.000 40.57593 ? 240 TYR C CZ  1 
ATOM   5207 O OH  . TYR C 1 241 ? 45.14181 51.06781 94.36151  1.000 42.46113 ? 240 TYR C OH  1 
ATOM   5208 N N   . ALA C 1 242 ? 43.86830 56.74964 95.13690  1.000 36.20966 ? 241 ALA C N   1 
ATOM   5209 C CA  . ALA C 1 242 ? 42.41477 56.78281 94.95851  1.000 38.12447 ? 241 ALA C CA  1 
ATOM   5210 C C   . ALA C 1 242 ? 41.89775 55.47405 94.36068  1.000 40.42854 ? 241 ALA C C   1 
ATOM   5211 O O   . ALA C 1 242 ? 40.98598 55.46565 93.52543  1.000 42.89687 ? 241 ALA C O   1 
ATOM   5212 C CB  . ALA C 1 242 ? 41.99372 57.97490 94.10129  1.000 34.24076 ? 241 ALA C CB  1 
ATOM   5213 N N   . GLY C 1 243 ? 42.49837 54.35049 94.75045  1.000 42.55473 ? 242 GLY C N   1 
ATOM   5214 C CA  . GLY C 1 243 ? 42.08566 53.04939 94.26062  1.000 39.01366 ? 242 GLY C CA  1 
ATOM   5215 C C   . GLY C 1 243 ? 42.66818 52.75996 92.89206  1.000 35.01295 ? 242 GLY C C   1 
ATOM   5216 O O   . GLY C 1 243 ? 43.31533 53.59665 92.26284  1.000 36.01386 ? 242 GLY C O   1 
ATOM   5217 N N   . SER C 1 244 ? 42.35726 51.56104 92.39489  1.000 37.25668 ? 243 SER C N   1 
ATOM   5218 C CA  . SER C 1 244 ? 43.01373 51.04665 91.19142  1.000 43.30100 ? 243 SER C CA  1 
ATOM   5219 C C   . SER C 1 244 ? 42.75264 51.91455 89.96275  1.000 36.58567 ? 243 SER C C   1 
ATOM   5220 O O   . SER C 1 244 ? 43.68349 52.19935 89.19612  1.000 33.60515 ? 243 SER C O   1 
ATOM   5221 C CB  . SER C 1 244 ? 42.56583 49.60710 90.91525  1.000 35.75837 ? 243 SER C CB  1 
ATOM   5222 N N   . TYR C 1 245 ? 41.50295 52.35659 89.75873  1.000 33.39178 ? 244 TYR C N   1 
ATOM   5223 C CA  . TYR C 1 245 ? 41.16386 53.00723 88.49158  1.000 35.60308 ? 244 TYR C CA  1 
ATOM   5224 C C   . TYR C 1 245 ? 41.62837 54.46145 88.46373  1.000 36.67520 ? 244 TYR C C   1 
ATOM   5225 O O   . TYR C 1 245 ? 42.30098 54.88677 87.51687  1.000 36.53219 ? 244 TYR C O   1 
ATOM   5226 C CB  . TYR C 1 245 ? 39.65815 52.90738 88.21050  1.000 40.06901 ? 244 TYR C CB  1 
ATOM   5227 C CG  . TYR C 1 245 ? 39.22840 53.62620 86.93605  1.000 39.23705 ? 244 TYR C CG  1 
ATOM   5228 C CD1 . TYR C 1 245 ? 39.40107 53.05170 85.67947  1.000 34.33880 ? 244 TYR C CD1 1 
ATOM   5229 C CD2 . TYR C 1 245 ? 38.66096 54.89513 86.99745  1.000 43.06021 ? 244 TYR C CD2 1 
ATOM   5230 C CE1 . TYR C 1 245 ? 39.01708 53.73225 84.52276  1.000 38.58648 ? 244 TYR C CE1 1 
ATOM   5231 C CE2 . TYR C 1 245 ? 38.27806 55.57358 85.85420  1.000 41.02656 ? 244 TYR C CE2 1 
ATOM   5232 C CZ  . TYR C 1 245 ? 38.45812 54.99560 84.62743  1.000 34.65130 ? 244 TYR C CZ  1 
ATOM   5233 O OH  . TYR C 1 245 ? 38.05766 55.70533 83.52546  1.000 31.35952 ? 244 TYR C OH  1 
ATOM   5234 N N   . ASN C 1 246 ? 41.32036 55.22899 89.50916  1.000 38.20675 ? 245 ASN C N   1 
ATOM   5235 C CA  . ASN C 1 246 ? 41.71556 56.62934 89.52670  1.000 32.26123 ? 245 ASN C CA  1 
ATOM   5236 C C   . ASN C 1 246 ? 43.17267 56.80675 89.94073  1.000 36.26619 ? 245 ASN C C   1 
ATOM   5237 O O   . ASN C 1 246 ? 43.77474 57.83428 89.61157  1.000 34.86409 ? 245 ASN C O   1 
ATOM   5238 C CB  . ASN C 1 246 ? 40.83684 57.41112 90.50608  1.000 29.98418 ? 245 ASN C CB  1 
ATOM   5239 C CG  . ASN C 1 246 ? 39.38556 57.46268 90.09690  1.000 26.39895 ? 245 ASN C CG  1 
ATOM   5240 O OD1 . ASN C 1 246 ? 39.05341 57.50399 88.92294  1.000 28.50627 ? 245 ASN C OD1 1 
ATOM   5241 N ND2 . ASN C 1 246 ? 38.51008 57.47437 91.07973  1.000 32.25400 ? 245 ASN C ND2 1 
ATOM   5242 N N   . PHE C 1 247 ? 43.75318 55.81430 90.62267  1.000 33.15109 ? 246 PHE C N   1 
ATOM   5243 C CA  . PHE C 1 247 ? 45.10639 55.86915 91.16342  1.000 29.80601 ? 246 PHE C CA  1 
ATOM   5244 C C   . PHE C 1 247 ? 45.36820 57.11571 92.01047  1.000 32.66591 ? 246 PHE C C   1 
ATOM   5245 O O   . PHE C 1 247 ? 45.14912 57.08394 93.22136  1.000 36.54173 ? 246 PHE C O   1 
ATOM   5246 C CB  . PHE C 1 247 ? 46.13542 55.75903 90.04943  1.000 25.75077 ? 246 PHE C CB  1 
ATOM   5247 C CG  . PHE C 1 247 ? 47.46174 55.33534 90.54471  1.000 27.53674 ? 246 PHE C CG  1 
ATOM   5248 C CD1 . PHE C 1 247 ? 47.61230 54.11519 91.16678  1.000 30.48641 ? 246 PHE C CD1 1 
ATOM   5249 C CD2 . PHE C 1 247 ? 48.54423 56.17403 90.46315  1.000 23.29490 ? 246 PHE C CD2 1 
ATOM   5250 C CE1 . PHE C 1 247 ? 48.83962 53.72430 91.65656  1.000 30.48832 ? 246 PHE C CE1 1 
ATOM   5251 C CE2 . PHE C 1 247 ? 49.76083 55.78413 90.95007  1.000 24.63201 ? 246 PHE C CE2 1 
ATOM   5252 C CZ  . PHE C 1 247 ? 49.90718 54.56075 91.55193  1.000 25.22675 ? 246 PHE C CZ  1 
ATOM   5253 N N   . TYR C 1 248 ? 45.87829 58.20161 91.43395  1.000 36.67795 ? 247 TYR C N   1 
ATOM   5254 C CA  . TYR C 1 248 ? 45.97673 59.44117 92.20493  1.000 39.54236 ? 247 TYR C CA  1 
ATOM   5255 C C   . TYR C 1 248 ? 44.90993 60.47467 91.89289  1.000 32.34969 ? 247 TYR C C   1 
ATOM   5256 O O   . TYR C 1 248 ? 44.30229 60.51484 90.82272  1.000 35.18219 ? 247 TYR C O   1 
ATOM   5257 C CB  . TYR C 1 248 ? 47.32377 60.17108 92.08936  1.000 32.09235 ? 247 TYR C CB  1 
ATOM   5258 C CG  . TYR C 1 248 ? 48.40603 59.79183 93.06609  1.000 35.26726 ? 247 TYR C CG  1 
ATOM   5259 C CD1 . TYR C 1 248 ? 48.19273 58.86772 94.07496  1.000 39.37162 ? 247 TYR C CD1 1 
ATOM   5260 C CD2 . TYR C 1 248 ? 49.53137 60.59437 93.16612  1.000 40.79482 ? 247 TYR C CD2 1 
ATOM   5261 C CE1 . TYR C 1 248 ? 49.17964 58.61991 95.03852  1.000 42.26131 ? 247 TYR C CE1 1 
ATOM   5262 C CE2 . TYR C 1 248 ? 50.49776 60.38090 94.12094  1.000 39.94159 ? 247 TYR C CE2 1 
ATOM   5263 C CZ  . TYR C 1 248 ? 50.32659 59.40177 95.05742  1.000 38.83012 ? 247 TYR C CZ  1 
ATOM   5264 O OH  . TYR C 1 248 ? 51.32318 59.23020 95.99563  1.000 33.03294 ? 247 TYR C OH  1 
ATOM   5265 N N   . VAL C 1 249 ? 44.75673 61.36804 92.85614  1.000 28.71055 ? 248 VAL C N   1 
ATOM   5266 C CA  . VAL C 1 249 ? 44.04399 62.62033 92.68597  1.000 35.60630 ? 248 VAL C CA  1 
ATOM   5267 C C   . VAL C 1 249 ? 44.82531 63.66752 93.46667  1.000 32.74667 ? 248 VAL C C   1 
ATOM   5268 O O   . VAL C 1 249 ? 45.52747 63.34428 94.43002  1.000 35.04296 ? 248 VAL C O   1 
ATOM   5269 C CB  . VAL C 1 249 ? 42.57665 62.52539 93.17621  1.000 35.68428 ? 248 VAL C CB  1 
ATOM   5270 C CG1 . VAL C 1 249 ? 41.83793 61.34523 92.49617  1.000 32.46971 ? 248 VAL C CG1 1 
ATOM   5271 C CG2 . VAL C 1 249 ? 42.53143 62.40173 94.69058  1.000 30.86654 ? 248 VAL C CG2 1 
ATOM   5272 N N   . PHE C 1 250 ? 44.69622 64.92958 93.04831  1.000 39.18071 ? 249 PHE C N   1 
ATOM   5273 C CA  . PHE C 1 250 ? 45.37859 66.06933 93.65142  1.000 29.82635 ? 249 PHE C CA  1 
ATOM   5274 C C   . PHE C 1 250 ? 44.36309 67.10721 94.09690  1.000 29.53641 ? 249 PHE C C   1 
ATOM   5275 O O   . PHE C 1 250 ? 43.19314 67.07386 93.70455  1.000 29.35021 ? 249 PHE C O   1 
ATOM   5276 C CB  . PHE C 1 250 ? 46.34911 66.74497 92.67827  1.000 29.31634 ? 249 PHE C CB  1 
ATOM   5277 C CG  . PHE C 1 250 ? 47.58923 65.96457 92.39086  1.000 26.87001 ? 249 PHE C CG  1 
ATOM   5278 C CD1 . PHE C 1 250 ? 47.56155 64.89248 91.51732  1.000 30.20349 ? 249 PHE C CD1 1 
ATOM   5279 C CD2 . PHE C 1 250 ? 48.79393 66.33045 92.96313  1.000 22.10860 ? 249 PHE C CD2 1 
ATOM   5280 C CE1 . PHE C 1 250 ? 48.71537 64.19874 91.23221  1.000 25.73841 ? 249 PHE C CE1 1 
ATOM   5281 C CE2 . PHE C 1 250 ? 49.94017 65.64025 92.69080  1.000 21.60361 ? 249 PHE C CE2 1 
ATOM   5282 C CZ  . PHE C 1 250 ? 49.90767 64.57336 91.82661  1.000 22.90181 ? 249 PHE C CZ  1 
ATOM   5283 N N   . GLY C 1 251 ? 44.84432 68.05308 94.94026  1.000 31.19308 ? 250 GLY C N   1 
ATOM   5284 C CA  . GLY C 1 251 ? 44.10606 69.27155 95.20819  1.000 35.19947 ? 250 GLY C CA  1 
ATOM   5285 C C   . GLY C 1 251 ? 44.45063 70.39865 94.22412  1.000 31.05768 ? 250 GLY C C   1 
ATOM   5286 O O   . GLY C 1 251 ? 45.37448 70.30402 93.41920  1.000 34.23925 ? 250 GLY C O   1 
ATOM   5287 N N   . ASN C 1 252 ? 43.69343 71.49285 94.30527  1.000 32.49338 ? 251 ASN C N   1 
ATOM   5288 C CA  . ASN C 1 252 ? 43.98722 72.61918 93.42281  1.000 41.88400 ? 251 ASN C CA  1 
ATOM   5289 C C   . ASN C 1 252 ? 45.12397 73.49899 93.93195  1.000 39.61910 ? 251 ASN C C   1 
ATOM   5290 O O   . ASN C 1 252 ? 45.41852 74.51963 93.30053  1.000 39.24758 ? 251 ASN C O   1 
ATOM   5291 C CB  . ASN C 1 252 ? 42.75202 73.49084 93.16102  1.000 32.86681 ? 251 ASN C CB  1 
ATOM   5292 C CG  . ASN C 1 252 ? 42.69089 73.97093 91.70331  1.000 42.42245 ? 251 ASN C CG  1 
ATOM   5293 O OD1 . ASN C 1 252 ? 42.90051 73.18101 90.77479  1.000 48.73102 ? 251 ASN C OD1 1 
ATOM   5294 N ND2 . ASN C 1 252 ? 42.42148 75.25563 91.49897  1.000 39.62418 ? 251 ASN C ND2 1 
ATOM   5295 N N   . GLY C 1 253 ? 45.74497 73.15738 95.05034  1.000 35.69241 ? 252 GLY C N   1 
ATOM   5296 C CA  . GLY C 1 253 ? 46.93142 73.91336 95.40122  1.000 31.66914 ? 252 GLY C CA  1 
ATOM   5297 C C   . GLY C 1 253 ? 46.61428 75.09610 96.28239  1.000 28.48816 ? 252 GLY C C   1 
ATOM   5298 O O   . GLY C 1 253 ? 45.51402 75.64437 96.27180  1.000 32.19976 ? 252 GLY C O   1 
ATOM   5299 N N   . THR C 1 254 ? 47.60211 75.46909 97.08882  1.000 30.83413 ? 253 THR C N   1 
ATOM   5300 C CA  . THR C 1 254 ? 47.48712 76.54407 98.06321  1.000 23.21443 ? 253 THR C CA  1 
ATOM   5301 C C   . THR C 1 254 ? 48.69700 77.42871 97.90300  1.000 27.44287 ? 253 THR C C   1 
ATOM   5302 O O   . THR C 1 254 ? 49.83603 76.94545 97.96127  1.000 24.00071 ? 253 THR C O   1 
ATOM   5303 C CB  . THR C 1 254 ? 47.42729 76.03234 99.49936  1.000 23.41553 ? 253 THR C CB  1 
ATOM   5304 O OG1 . THR C 1 254 ? 46.29721 75.16507 99.64290  1.000 27.32783 ? 253 THR C OG1 1 
ATOM   5305 C CG2 . THR C 1 254 ? 47.35477 77.20625 100.47922 1.000 19.94255 ? 253 THR C CG2 1 
ATOM   5306 N N   . LYS C 1 255 ? 48.44457 78.71024 97.67342  1.000 29.65661 ? 254 LYS C N   1 
ATOM   5307 C CA  . LYS C 1 255 ? 49.50524 79.69889 97.61829  1.000 28.01864 ? 254 LYS C CA  1 
ATOM   5308 C C   . LYS C 1 255 ? 49.90579 80.13962 99.02653  1.000 28.40370 ? 254 LYS C C   1 
ATOM   5309 O O   . LYS C 1 255 ? 49.15514 80.82332 99.73132  1.000 29.65615 ? 254 LYS C O   1 
ATOM   5310 C CB  . LYS C 1 255 ? 49.06153 80.85227 96.73505  1.000 31.38687 ? 254 LYS C CB  1 
ATOM   5311 C CG  . LYS C 1 255 ? 50.01461 82.00759 96.77554  1.000 42.74262 ? 254 LYS C CG  1 
ATOM   5312 C CD  . LYS C 1 255 ? 51.36412 81.64179 96.23687  1.000 44.65856 ? 254 LYS C CD  1 
ATOM   5313 C CE  . LYS C 1 255 ? 52.22683 82.83416 96.05598  1.000 51.78553 ? 254 LYS C CE  1 
ATOM   5314 N NZ  . LYS C 1 255 ? 53.60629 82.53716 95.56148  1.000 65.87346 ? 254 LYS C NZ  1 
ATOM   5315 N N   . VAL C 1 256 ? 51.09817 79.76696 99.41680  1.000 26.53776 ? 255 VAL C N   1 
ATOM   5316 C CA  . VAL C 1 256 ? 51.67970 80.21136 100.66499 1.000 27.89942 ? 255 VAL C CA  1 
ATOM   5317 C C   . VAL C 1 256 ? 52.51402 81.43937 100.41678 1.000 30.15916 ? 255 VAL C C   1 
ATOM   5318 O O   . VAL C 1 256 ? 53.30619 81.47965 99.47268  1.000 37.58504 ? 255 VAL C O   1 
ATOM   5319 C CB  . VAL C 1 256 ? 52.52474 79.10383 101.30327 1.000 33.44303 ? 255 VAL C CB  1 
ATOM   5320 C CG1 . VAL C 1 256 ? 53.34451 79.69162 102.42675 1.000 33.89378 ? 255 VAL C CG1 1 
ATOM   5321 C CG2 . VAL C 1 256 ? 51.60175 78.05791 101.88103 1.000 34.48279 ? 255 VAL C CG2 1 
ATOM   5322 N N   . THR C 1 257 ? 52.31056 82.45045 101.23930 1.000 33.77512 ? 256 THR C N   1 
ATOM   5323 C CA  . THR C 1 257 ? 53.04779 83.69216 101.12781 1.000 36.21585 ? 256 THR C CA  1 
ATOM   5324 C C   . THR C 1 257 ? 53.71954 83.99957 102.45316 1.000 34.70526 ? 256 THR C C   1 
ATOM   5325 O O   . THR C 1 257 ? 53.11854 83.83507 103.51693 1.000 32.55436 ? 256 THR C O   1 
ATOM   5326 C CB  . THR C 1 257 ? 52.14012 84.83360 100.70259 1.000 40.65682 ? 256 THR C CB  1 
ATOM   5327 O OG1 . THR C 1 257 ? 51.78393 84.64063 99.32613  1.000 38.90675 ? 256 THR C OG1 1 
ATOM   5328 C CG2 . THR C 1 257 ? 52.83729 86.17614 100.88030 1.000 33.56543 ? 256 THR C CG2 1 
ATOM   5329 N N   . VAL C 1 258 ? 54.97665 84.41828 102.37564 1.000 37.15894 ? 257 VAL C N   1 
ATOM   5330 C CA  . VAL C 1 258 ? 55.77632 84.78865 103.53395 1.000 37.85861 ? 257 VAL C CA  1 
ATOM   5331 C C   . VAL C 1 258 ? 55.89846 86.30619 103.50813 1.000 38.71250 ? 257 VAL C C   1 
ATOM   5332 O O   . VAL C 1 258 ? 56.33668 86.87740 102.50091 1.000 39.19080 ? 257 VAL C O   1 
ATOM   5333 C CB  . VAL C 1 258 ? 57.15440 84.11139 103.50914 1.000 36.57015 ? 257 VAL C CB  1 
ATOM   5334 C CG1 . VAL C 1 258 ? 57.84508 84.28218 104.84231 1.000 36.68180 ? 257 VAL C CG1 1 
ATOM   5335 C CG2 . VAL C 1 258 ? 57.01070 82.64055 103.14555 1.000 35.68527 ? 257 VAL C CG2 1 
ATOM   5336 N N   . LEU C 1 259 ? 55.48682 86.95347 104.60334 1.000 40.35475 ? 258 LEU C N   1 
ATOM   5337 C CA  . LEU C 1 259 ? 55.36394 88.41369 104.68916 1.000 35.37606 ? 258 LEU C CA  1 
ATOM   5338 C C   . LEU C 1 259 ? 56.61732 89.07757 105.23839 1.000 37.74852 ? 258 LEU C C   1 
ATOM   5339 O O   . LEU C 1 259 ? 56.78944 90.29451 105.10575 1.000 48.54629 ? 258 LEU C O   1 
ATOM   5340 C CB  . LEU C 1 259 ? 54.15897 88.80114 105.56377 1.000 34.83555 ? 258 LEU C CB  1 
ATOM   5341 C CG  . LEU C 1 259 ? 52.85256 88.04278 105.31307 1.000 29.80273 ? 258 LEU C CG  1 
ATOM   5342 C CD1 . LEU C 1 259 ? 51.73867 88.48437 106.25006 1.000 27.91846 ? 258 LEU C CD1 1 
ATOM   5343 C CD2 . LEU C 1 259 ? 52.42020 88.19679 103.87467 1.000 29.38810 ? 258 LEU C CD2 1 
HETATM 5344 S S   . SO4 D 2 .   ? 72.48155 12.52884 91.17947  1.000 45.99197 ? 301 SO4 A S   1 
HETATM 5345 O O1  . SO4 D 2 .   ? 73.66916 11.98742 90.51418  1.000 31.83241 ? 301 SO4 A O1  1 
HETATM 5346 O O2  . SO4 D 2 .   ? 71.29014 12.15147 90.41507  1.000 36.80113 ? 301 SO4 A O2  1 
HETATM 5347 O O3  . SO4 D 2 .   ? 72.40528 12.03512 92.55076  1.000 41.69256 ? 301 SO4 A O3  1 
HETATM 5348 O O4  . SO4 D 2 .   ? 72.57822 13.98606 91.26003  1.000 47.30215 ? 301 SO4 A O4  1 
HETATM 5349 S S   . SO4 E 2 .   ? 51.52309 12.31801 85.56490  1.000 61.00710 ? 302 SO4 A S   1 
HETATM 5350 O O1  . SO4 E 2 .   ? 52.86769 11.92636 85.13678  1.000 48.75071 ? 302 SO4 A O1  1 
HETATM 5351 O O2  . SO4 E 2 .   ? 50.87905 13.13012 84.54156  1.000 47.90254 ? 302 SO4 A O2  1 
HETATM 5352 O O3  . SO4 E 2 .   ? 50.74177 11.09588 85.76118  1.000 64.32024 ? 302 SO4 A O3  1 
HETATM 5353 O O4  . SO4 E 2 .   ? 51.59892 13.09005 86.80887  1.000 47.64314 ? 302 SO4 A O4  1 
HETATM 5354 S S   . SO4 F 2 .   ? 36.56695 30.31532 56.77994  1.000 46.73438 ? 301 SO4 B S   1 
HETATM 5355 O O1  . SO4 F 2 .   ? 37.11305 31.06914 55.65493  1.000 51.91657 ? 301 SO4 B O1  1 
HETATM 5356 O O2  . SO4 F 2 .   ? 35.10963 30.44866 56.82397  1.000 43.56710 ? 301 SO4 B O2  1 
HETATM 5357 O O3  . SO4 F 2 .   ? 36.93142 28.91001 56.62234  1.000 56.43386 ? 301 SO4 B O3  1 
HETATM 5358 O O4  . SO4 F 2 .   ? 37.16754 30.82285 58.00515  1.000 48.07654 ? 301 SO4 B O4  1 
HETATM 5359 S S   . SO4 G 2 .   ? 49.29244 47.48844 93.32515  1.000 55.23105 ? 301 SO4 C S   1 
HETATM 5360 O O1  . SO4 G 2 .   ? 50.28492 48.14347 92.45368  1.000 36.10721 ? 301 SO4 C O1  1 
HETATM 5361 O O2  . SO4 G 2 .   ? 48.24323 46.86429 92.51830  1.000 48.44514 ? 301 SO4 C O2  1 
HETATM 5362 O O3  . SO4 G 2 .   ? 49.96825 46.48851 94.16443  1.000 44.36703 ? 301 SO4 C O3  1 
HETATM 5363 O O4  . SO4 G 2 .   ? 48.62297 48.45537 94.18987  1.000 42.26116 ? 301 SO4 C O4  1 
HETATM 5364 O O   . HOH H 3 .   ? 73.48537 34.90287 73.69802  1.000 36.48456 ? 401 HOH A O   1 
HETATM 5365 O O   . HOH H 3 .   ? 67.62458 36.66545 80.74715  1.000 30.40017 ? 402 HOH A O   1 
HETATM 5366 O O   . HOH H 3 .   ? 73.24924 18.34472 84.46477  1.000 29.54475 ? 403 HOH A O   1 
HETATM 5367 O O   . HOH H 3 .   ? 52.79992 28.79117 84.59884  1.000 32.22800 ? 404 HOH A O   1 
HETATM 5368 O O   . HOH H 3 .   ? 50.65193 9.09197  86.16703  1.000 24.84529 ? 405 HOH A O   1 
HETATM 5369 O O   . HOH H 3 .   ? 68.56222 26.48361 103.03770 1.000 35.31911 ? 406 HOH A O   1 
HETATM 5370 O O   . HOH H 3 .   ? 73.37525 34.28361 96.28481  1.000 34.79223 ? 407 HOH A O   1 
HETATM 5371 O O   . HOH H 3 .   ? 66.28839 41.75761 89.38874  1.000 35.55062 ? 408 HOH A O   1 
HETATM 5372 O O   . HOH H 3 .   ? 76.04117 41.51082 99.26204  1.000 31.22780 ? 409 HOH A O   1 
HETATM 5373 O O   . HOH H 3 .   ? 73.62504 25.30904 74.34278  1.000 26.16374 ? 410 HOH A O   1 
HETATM 5374 O O   . HOH H 3 .   ? 52.97821 21.38667 100.76818 1.000 35.91345 ? 411 HOH A O   1 
HETATM 5375 O O   . HOH H 3 .   ? 75.97773 24.82131 89.03407  1.000 26.93012 ? 412 HOH A O   1 
HETATM 5376 O O   . HOH H 3 .   ? 79.73468 48.81928 88.92495  1.000 31.07651 ? 413 HOH A O   1 
HETATM 5377 O O   . HOH H 3 .   ? 78.35045 14.44797 98.63674  1.000 28.10328 ? 414 HOH A O   1 
HETATM 5378 O O   . HOH H 3 .   ? 82.29315 30.69168 100.65969 1.000 35.02730 ? 415 HOH A O   1 
HETATM 5379 O O   . HOH H 3 .   ? 74.16720 41.59306 100.12065 1.000 26.30520 ? 416 HOH A O   1 
HETATM 5380 O O   . HOH H 3 .   ? 52.45493 9.42673  85.25674  1.000 38.30348 ? 417 HOH A O   1 
HETATM 5381 O O   . HOH H 3 .   ? 89.69641 31.34499 88.88653  1.000 38.43500 ? 418 HOH A O   1 
HETATM 5382 O O   . HOH H 3 .   ? 81.74726 30.57994 73.34332  1.000 40.26243 ? 419 HOH A O   1 
HETATM 5383 O O   . HOH H 3 .   ? 50.05922 27.17942 105.41194 1.000 29.34825 ? 420 HOH A O   1 
HETATM 5384 O O   . HOH H 3 .   ? 63.15295 37.98980 101.92426 1.000 34.29700 ? 421 HOH A O   1 
HETATM 5385 O O   . HOH H 3 .   ? 73.37470 15.10557 94.35835  1.000 39.87939 ? 422 HOH A O   1 
HETATM 5386 O O   . HOH H 3 .   ? 70.67141 28.70975 73.77021  1.000 29.46349 ? 423 HOH A O   1 
HETATM 5387 O O   . HOH H 3 .   ? 73.37012 29.85701 97.85489  1.000 31.82879 ? 424 HOH A O   1 
HETATM 5388 O O   . HOH H 3 .   ? 66.49575 21.50428 74.25724  1.000 24.71415 ? 425 HOH A O   1 
HETATM 5389 O O   . HOH H 3 .   ? 84.20877 29.59911 85.89219  1.000 26.92997 ? 426 HOH A O   1 
HETATM 5390 O O   . HOH H 3 .   ? 46.20121 36.43277 101.15628 1.000 33.59976 ? 427 HOH A O   1 
HETATM 5391 O O   . HOH H 3 .   ? 88.18324 32.41151 73.10187  1.000 28.68233 ? 428 HOH A O   1 
HETATM 5392 O O   . HOH H 3 .   ? 77.66924 39.85390 72.02942  1.000 29.11235 ? 429 HOH A O   1 
HETATM 5393 O O   . HOH H 3 .   ? 67.30474 15.86278 83.75873  1.000 28.60018 ? 430 HOH A O   1 
HETATM 5394 O O   . HOH H 3 .   ? 71.53408 27.38138 96.91305  1.000 34.14654 ? 431 HOH A O   1 
HETATM 5395 O O   . HOH H 3 .   ? 72.74508 12.53607 76.34592  1.000 28.46349 ? 432 HOH A O   1 
HETATM 5396 O O   . HOH H 3 .   ? 87.99583 15.00781 90.92171  1.000 35.05659 ? 433 HOH A O   1 
HETATM 5397 O O   . HOH H 3 .   ? 71.57821 9.84416  84.66851  1.000 39.40623 ? 434 HOH A O   1 
HETATM 5398 O O   . HOH H 3 .   ? 52.13246 24.98139 107.42055 1.000 33.02378 ? 435 HOH A O   1 
HETATM 5399 O O   . HOH H 3 .   ? 62.37989 30.46121 79.56507  1.000 33.02998 ? 436 HOH A O   1 
HETATM 5400 O O   . HOH H 3 .   ? 66.47479 38.93380 104.64282 1.000 48.63219 ? 437 HOH A O   1 
HETATM 5401 O O   . HOH H 3 .   ? 88.79289 25.00443 101.55193 1.000 33.51117 ? 438 HOH A O   1 
HETATM 5402 O O   . HOH H 3 .   ? 60.24057 24.75153 65.20181  1.000 25.85998 ? 439 HOH A O   1 
HETATM 5403 O O   . HOH H 3 .   ? 65.85379 13.63532 85.67471  1.000 17.30388 ? 440 HOH A O   1 
HETATM 5404 O O   . HOH H 3 .   ? 70.45682 15.88986 77.17874  1.000 29.91136 ? 441 HOH A O   1 
HETATM 5405 O O   . HOH H 3 .   ? 60.69627 30.33786 107.59332 1.000 39.81306 ? 442 HOH A O   1 
HETATM 5406 O O   . HOH H 3 .   ? 55.77738 15.07734 95.06929  1.000 17.05487 ? 443 HOH A O   1 
HETATM 5407 O O   . HOH H 3 .   ? 79.55773 14.01103 96.18718  1.000 26.60326 ? 444 HOH A O   1 
HETATM 5408 O O   . HOH H 3 .   ? 86.06767 23.46772 103.47413 1.000 37.62472 ? 445 HOH A O   1 
HETATM 5409 O O   . HOH H 3 .   ? 49.91090 35.32425 88.99796  1.000 26.63962 ? 446 HOH A O   1 
HETATM 5410 O O   . HOH H 3 .   ? 90.67885 30.73092 87.12941  1.000 31.94979 ? 447 HOH A O   1 
HETATM 5411 O O   . HOH H 3 .   ? 77.75085 13.48764 95.17487  1.000 34.15461 ? 448 HOH A O   1 
HETATM 5412 O O   . HOH H 3 .   ? 91.21732 23.62658 100.71819 1.000 28.72397 ? 449 HOH A O   1 
HETATM 5413 O O   . HOH H 3 .   ? 51.36229 35.25305 87.11495  1.000 20.29616 ? 450 HOH A O   1 
HETATM 5414 O O   . HOH H 3 .   ? 67.82199 42.30859 91.83302  1.000 27.38488 ? 451 HOH A O   1 
HETATM 5415 O O   . HOH H 3 .   ? 73.91576 28.87305 67.96185  1.000 31.06600 ? 452 HOH A O   1 
HETATM 5416 O O   . HOH H 3 .   ? 48.80009 35.30112 87.15936  1.000 32.31874 ? 453 HOH A O   1 
HETATM 5417 O O   . HOH H 3 .   ? 48.05534 40.85417 93.01612  1.000 31.33465 ? 454 HOH A O   1 
HETATM 5418 O O   . HOH H 3 .   ? 71.27044 45.37532 100.48988 1.000 25.51585 ? 455 HOH A O   1 
HETATM 5419 O O   . HOH H 3 .   ? 74.59450 26.83240 67.57569  1.000 35.08868 ? 456 HOH A O   1 
HETATM 5420 O O   . HOH H 3 .   ? 72.53567 48.28695 100.31146 1.000 12.46814 ? 457 HOH A O   1 
HETATM 5421 O O   . HOH I 3 .   ? 42.43511 27.59284 51.92721  1.000 30.57052 ? 401 HOH B O   1 
HETATM 5422 O O   . HOH I 3 .   ? 29.43224 30.06198 46.64884  1.000 34.43891 ? 402 HOH B O   1 
HETATM 5423 O O   . HOH I 3 .   ? 47.66446 38.15039 44.11821  1.000 14.28854 ? 403 HOH B O   1 
HETATM 5424 O O   . HOH I 3 .   ? 30.14177 53.19645 54.80371  1.000 37.01530 ? 404 HOH B O   1 
HETATM 5425 O O   . HOH I 3 .   ? 45.24534 43.58806 34.44466  1.000 32.86422 ? 405 HOH B O   1 
HETATM 5426 O O   . HOH I 3 .   ? 35.93303 56.18045 46.26706  1.000 20.36968 ? 406 HOH B O   1 
HETATM 5427 O O   . HOH I 3 .   ? 14.74852 54.45099 40.90860  1.000 43.84567 ? 407 HOH B O   1 
HETATM 5428 O O   . HOH I 3 .   ? 43.38166 66.14468 60.60918  1.000 17.60044 ? 408 HOH B O   1 
HETATM 5429 O O   . HOH I 3 .   ? 56.65586 53.80670 60.98374  1.000 27.87485 ? 409 HOH B O   1 
HETATM 5430 O O   . HOH I 3 .   ? 55.06767 38.18206 59.71561  1.000 30.90203 ? 410 HOH B O   1 
HETATM 5431 O O   . HOH I 3 .   ? 20.53451 41.40484 51.95734  1.000 45.94239 ? 411 HOH B O   1 
HETATM 5432 O O   . HOH I 3 .   ? 54.33155 46.90362 60.13971  1.000 26.42750 ? 412 HOH B O   1 
HETATM 5433 O O   . HOH I 3 .   ? 40.34973 33.23840 47.78398  1.000 24.93117 ? 413 HOH B O   1 
HETATM 5434 O O   . HOH I 3 .   ? 23.67916 60.19787 42.91002  1.000 42.63072 ? 414 HOH B O   1 
HETATM 5435 O O   . HOH I 3 .   ? 30.48649 29.65577 36.62521  1.000 30.60256 ? 415 HOH B O   1 
HETATM 5436 O O   . HOH I 3 .   ? 47.99820 36.08908 44.45384  1.000 23.93688 ? 416 HOH B O   1 
HETATM 5437 O O   . HOH I 3 .   ? 37.39800 58.62999 63.68973  1.000 22.69145 ? 417 HOH B O   1 
HETATM 5438 O O   . HOH I 3 .   ? 52.91921 52.46146 66.14931  1.000 25.25935 ? 418 HOH B O   1 
HETATM 5439 O O   . HOH I 3 .   ? 47.30845 47.38570 63.25756  1.000 28.61520 ? 419 HOH B O   1 
HETATM 5440 O O   . HOH I 3 .   ? 30.25848 42.96523 60.61520  1.000 45.31799 ? 420 HOH B O   1 
HETATM 5441 O O   . HOH I 3 .   ? 35.94798 29.94464 41.59739  1.000 23.27930 ? 421 HOH B O   1 
HETATM 5442 O O   . HOH I 3 .   ? 23.98630 32.81557 51.68758  1.000 35.33812 ? 422 HOH B O   1 
HETATM 5443 O O   . HOH I 3 .   ? 20.85382 36.35008 64.31947  1.000 29.79439 ? 423 HOH B O   1 
HETATM 5444 O O   . HOH I 3 .   ? 48.46959 49.32375 69.84464  1.000 31.66232 ? 424 HOH B O   1 
HETATM 5445 O O   . HOH I 3 .   ? 27.01998 42.02956 59.73563  1.000 27.44027 ? 425 HOH B O   1 
HETATM 5446 O O   . HOH I 3 .   ? 37.79665 50.28651 39.44698  1.000 40.11835 ? 426 HOH B O   1 
HETATM 5447 O O   . HOH I 3 .   ? 53.03782 41.59142 64.37398  1.000 22.12179 ? 427 HOH B O   1 
HETATM 5448 O O   . HOH I 3 .   ? 38.52451 47.80999 74.37836  1.000 17.53036 ? 428 HOH B O   1 
HETATM 5449 O O   . HOH I 3 .   ? 37.91480 31.05439 48.52459  1.000 14.20387 ? 429 HOH B O   1 
HETATM 5450 O O   . HOH I 3 .   ? 51.26197 48.65040 69.89779  1.000 34.01291 ? 430 HOH B O   1 
HETATM 5451 O O   . HOH I 3 .   ? 32.42484 46.24620 35.26548  1.000 28.77829 ? 431 HOH B O   1 
HETATM 5452 O O   . HOH I 3 .   ? 52.19799 37.42593 53.39568  1.000 13.30372 ? 432 HOH B O   1 
HETATM 5453 O O   . HOH I 3 .   ? 43.29500 56.08745 47.97530  1.000 26.44866 ? 433 HOH B O   1 
HETATM 5454 O O   . HOH I 3 .   ? 51.39612 42.21529 47.83121  1.000 22.68948 ? 434 HOH B O   1 
HETATM 5455 O O   . HOH I 3 .   ? 58.09948 46.97164 46.69193  1.000 31.91543 ? 435 HOH B O   1 
HETATM 5456 O O   . HOH I 3 .   ? 59.52557 56.21481 52.97804  1.000 27.67812 ? 436 HOH B O   1 
HETATM 5457 O O   . HOH I 3 .   ? 37.31447 42.71806 75.87641  1.000 35.96537 ? 437 HOH B O   1 
HETATM 5458 O O   . HOH I 3 .   ? 43.69036 47.41358 74.93836  1.000 30.32684 ? 438 HOH B O   1 
HETATM 5459 O O   . HOH I 3 .   ? 36.64008 31.20943 62.48576  1.000 42.41085 ? 439 HOH B O   1 
HETATM 5460 O O   . HOH I 3 .   ? 23.55990 38.00426 33.44962  1.000 30.65906 ? 440 HOH B O   1 
HETATM 5461 O O   . HOH I 3 .   ? 48.12237 33.50060 47.53037  1.000 25.02730 ? 441 HOH B O   1 
HETATM 5462 O O   . HOH I 3 .   ? 52.15112 43.88906 67.12862  1.000 29.52825 ? 442 HOH B O   1 
HETATM 5463 O O   . HOH I 3 .   ? 37.73658 61.21161 68.30869  1.000 37.29792 ? 443 HOH B O   1 
HETATM 5464 O O   . HOH I 3 .   ? 20.39986 54.36982 36.84833  1.000 26.91294 ? 444 HOH B O   1 
HETATM 5465 O O   . HOH I 3 .   ? 21.53521 52.49017 37.80076  1.000 40.17138 ? 445 HOH B O   1 
HETATM 5466 O O   . HOH I 3 .   ? 29.62913 62.79110 59.42355  1.000 34.13752 ? 446 HOH B O   1 
HETATM 5467 O O   . HOH I 3 .   ? 54.37946 50.57100 65.07880  1.000 29.69526 ? 447 HOH B O   1 
HETATM 5468 O O   . HOH I 3 .   ? 39.12609 41.47572 77.85061  1.000 31.95426 ? 448 HOH B O   1 
HETATM 5469 O O   . HOH I 3 .   ? 37.81296 64.13375 68.25125  1.000 33.28273 ? 449 HOH B O   1 
HETATM 5470 O O   . HOH I 3 .   ? 30.23826 64.93787 58.40314  1.000 35.91630 ? 450 HOH B O   1 
HETATM 5471 O O   . HOH J 3 .   ? 47.38182 70.32608 85.67601  1.000 25.86609 ? 401 HOH C O   1 
HETATM 5472 O O   . HOH J 3 .   ? 54.88622 54.49826 100.55715 1.000 25.91854 ? 402 HOH C O   1 
HETATM 5473 O O   . HOH J 3 .   ? 42.37631 76.93423 90.34352  1.000 22.65649 ? 403 HOH C O   1 
HETATM 5474 O O   . HOH J 3 .   ? 58.00349 42.97789 99.73829  1.000 58.72713 ? 404 HOH C O   1 
HETATM 5475 O O   . HOH J 3 .   ? 50.33658 76.95706 112.40871 1.000 24.55463 ? 405 HOH C O   1 
HETATM 5476 O O   . HOH J 3 .   ? 62.81516 73.49975 100.88721 1.000 36.35603 ? 406 HOH C O   1 
HETATM 5477 O O   . HOH J 3 .   ? 46.34112 54.58057 75.63378  1.000 29.49104 ? 407 HOH C O   1 
HETATM 5478 O O   . HOH J 3 .   ? 58.30973 73.01480 75.85625  1.000 42.95439 ? 408 HOH C O   1 
HETATM 5479 O O   . HOH J 3 .   ? 64.63432 63.18969 74.20371  1.000 33.57958 ? 409 HOH C O   1 
HETATM 5480 O O   . HOH J 3 .   ? 45.80272 66.45566 111.15128 1.000 29.17379 ? 410 HOH C O   1 
HETATM 5481 O O   . HOH J 3 .   ? 63.06046 66.15467 98.61480  1.000 30.06599 ? 411 HOH C O   1 
HETATM 5482 O O   . HOH J 3 .   ? 49.49270 44.50844 88.53547  1.000 38.90410 ? 412 HOH C O   1 
HETATM 5483 O O   . HOH J 3 .   ? 53.75266 60.68530 95.99641  1.000 29.44052 ? 413 HOH C O   1 
HETATM 5484 O O   . HOH J 3 .   ? 61.39280 46.92647 84.57717  1.000 19.65988 ? 414 HOH C O   1 
HETATM 5485 O O   . HOH J 3 .   ? 66.00597 63.97550 106.21473 1.000 35.30750 ? 415 HOH C O   1 
HETATM 5486 O O   . HOH J 3 .   ? 45.60247 72.55712 79.38321  1.000 25.52392 ? 416 HOH C O   1 
HETATM 5487 O O   . HOH J 3 .   ? 62.25930 69.93383 77.42195  1.000 31.52728 ? 417 HOH C O   1 
HETATM 5488 O O   . HOH J 3 .   ? 58.81895 86.58432 102.45534 1.000 39.95454 ? 418 HOH C O   1 
HETATM 5489 O O   . HOH J 3 .   ? 69.12534 54.74471 86.26667  1.000 26.22765 ? 419 HOH C O   1 
HETATM 5490 O O   . HOH J 3 .   ? 44.01773 53.31830 86.48166  1.000 34.05973 ? 420 HOH C O   1 
HETATM 5491 O O   . HOH J 3 .   ? 58.80729 50.58957 92.27835  1.000 21.63803 ? 421 HOH C O   1 
HETATM 5492 O O   . HOH J 3 .   ? 36.11573 68.27319 98.13902  1.000 38.78922 ? 422 HOH C O   1 
HETATM 5493 O O   . HOH J 3 .   ? 48.94619 64.70761 105.88794 1.000 25.28434 ? 423 HOH C O   1 
HETATM 5494 O O   . HOH J 3 .   ? 53.46965 71.07499 64.98713  1.000 34.59491 ? 424 HOH C O   1 
HETATM 5495 O O   . HOH J 3 .   ? 64.36056 60.02626 101.45210 1.000 26.86290 ? 425 HOH C O   1 
HETATM 5496 O O   . HOH J 3 .   ? 55.17067 53.71047 96.57214  1.000 24.49890 ? 426 HOH C O   1 
HETATM 5497 O O   . HOH J 3 .   ? 55.62257 60.38391 67.60637  1.000 22.40907 ? 427 HOH C O   1 
HETATM 5498 O O   . HOH J 3 .   ? 64.20914 65.59759 112.59031 1.000 37.55868 ? 428 HOH C O   1 
HETATM 5499 O O   . HOH J 3 .   ? 64.29557 63.69411 107.50023 1.000 35.70941 ? 429 HOH C O   1 
HETATM 5500 O O   . HOH J 3 .   ? 50.23954 81.78229 109.76152 1.000 27.50969 ? 430 HOH C O   1 
HETATM 5501 O O   . HOH J 3 .   ? 43.06934 65.99073 78.23319  1.000 27.36661 ? 431 HOH C O   1 
HETATM 5502 O O   . HOH J 3 .   ? 49.24565 83.93586 100.19188 1.000 32.69079 ? 432 HOH C O   1 
HETATM 5503 O O   . HOH J 3 .   ? 47.14692 49.99993 99.17569  1.000 31.07326 ? 433 HOH C O   1 
HETATM 5504 O O   . HOH J 3 .   ? 40.70370 72.67477 95.96634  1.000 29.61507 ? 434 HOH C O   1 
HETATM 5505 O O   . HOH J 3 .   ? 68.86792 44.95282 91.25788  1.000 12.04831 ? 435 HOH C O   1 
HETATM 5506 O O   . HOH J 3 .   ? 46.30528 75.72677 75.72797  1.000 29.61087 ? 436 HOH C O   1 
HETATM 5507 O O   . HOH J 3 .   ? 65.02314 56.81176 69.72948  1.000 24.18070 ? 437 HOH C O   1 
HETATM 5508 O O   . HOH J 3 .   ? 65.17906 67.69539 84.85743  1.000 34.17221 ? 438 HOH C O   1 
HETATM 5509 O O   . HOH J 3 .   ? 50.15919 43.70469 95.22442  1.000 40.42035 ? 439 HOH C O   1 
HETATM 5510 O O   . HOH J 3 .   ? 44.37458 69.36148 90.50045  1.000 30.57312 ? 440 HOH C O   1 
HETATM 5511 O O   . HOH J 3 .   ? 41.21364 49.88964 95.75475  1.000 24.59046 ? 441 HOH C O   1 
HETATM 5512 O O   . HOH J 3 .   ? 64.04797 68.51778 82.47701  1.000 29.91208 ? 442 HOH C O   1 
HETATM 5513 O O   . HOH J 3 .   ? 65.65429 53.98569 97.20157  1.000 22.06663 ? 443 HOH C O   1 
HETATM 5514 O O   . HOH J 3 .   ? 63.64817 69.61935 74.83834  1.000 22.06082 ? 444 HOH C O   1 
HETATM 5515 O O   . HOH J 3 .   ? 65.35143 66.37309 111.04365 1.000 41.17618 ? 445 HOH C O   1 
HETATM 5516 O O   . HOH J 3 .   ? 45.13047 49.14107 98.52609  1.000 29.87663 ? 446 HOH C O   1 
HETATM 5517 O O   . HOH J 3 .   ? 62.25659 63.66715 72.92565  1.000 23.83160 ? 447 HOH C O   1 
HETATM 5518 O O   . HOH J 3 .   ? 48.13204 43.40871 93.50202  1.000 29.53823 ? 448 HOH C O   1 
HETATM 5519 O O   . HOH J 3 .   ? 67.03636 56.44771 96.77421  1.000 20.39913 ? 449 HOH C O   1 
HETATM 5520 O O   . HOH J 3 .   ? 42.92128 57.32680 110.24798 1.000 24.32869 ? 450 HOH C O   1 
# 
