data_9D7V
# 
_entry.id   9D7V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9D7V         pdb_00009d7v 10.2210/pdb9d7v/pdb 
WWPDB D_1000287382 ?            ?                   
EMDB  EMD-46617    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_database_PDB_caveat.id 
_database_PDB_caveat.text 
1 'Residues VAL A 343 and ARG A 344 that are next to each other in the sample sequence are not properly linked.' 
2 
;Residues ARG A 344 and VAL A 345 that are next to each other in the sample sequence are not properly linked: distance between C and N is 1.60.
;
3 'Residues PHE A 435 and TRP A 436 that are next to each other in the sample sequence are not properly linked.' 
4 
;Residues TRP A 436 and LYS A 437 that are next to each other in the sample sequence are not properly linked: distance between C and N is 1.16.
;
5 
;Residues LEU A 620 and TRP A 621 that are next to each other in the sample sequence are not properly linked: distance between C and N is 1.15.
;
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9D7V 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'The spd-bound structure' 
_pdbx_database_related.db_id          EMD-46617 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              min.lu@rosalindfranklin.edu 
_pdbx_contact_author.name_first         Min 
_pdbx_contact_author.name_last          Lu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3596-7559 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lu, M.'  1 0000-0002-3596-7559 
'Liu, B.' 2 0000-0002-6581-780X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                4142 
_citation.page_last                 4142 
_citation.title                     'Structure and mechanism of human vesicular polyamine transporter.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-59549-w 
_citation.pdbx_database_id_PubMed   40319071 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Guo, Y.'      1 ?                   
primary 'Yang, G.'     2 ?                   
primary 'Liu, H.'      3 ?                   
primary 'Chai, J.'     4 0000-0002-4760-5811 
primary 'Chen, J.'     5 ?                   
primary 'Shanklin, J.' 6 0000-0002-6774-8043 
primary 'Liu, Q.'      7 0000-0002-1179-290X 
primary 'Liu, B.'      8 0000-0002-6581-780X 
primary 'Lu, M.'       9 0000-0002-3596-7559 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Green fluorescence protein,MFS-type transporter SLC18B1,membrane protein spd' 82119.766 1 ? ? ? ? 
2 non-polymer syn SPERMIDINE                                                                     145.246   1 ? ? ? ? 
3 water       nat water                                                                          18.015    1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Solute carrier family 18 member B1,Vesicular polyamine transporter,VPAT' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;VSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKLICTTGKLPVPWPTLVTTLGYGLQCFARYPDHMKQ
HDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYITADKQKNG
IKANFKIRHNIEDGGVQLADHYQQNTPIGDGPVLLPDNHYLSYQSKLSKDPNEKRDHMVLLEFVTAAGITTPGWLSREQV
FVLISAASVNLGSMMCYSILGPFFPKEAEKKGASNTIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVT
ILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAFPNNVATVLGSLETFSGLGLILGPPVGGFLYQSFGY
EVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPKVGLIAFVINSLSSCFGFLDPTLSLFVLEKFNLPAGYVG
LVFLGMALSYAISSPLFGLLSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGLSAGMSIIPTF
PEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGLWALISGLAMGLFYLLEYSQVQ
LVESGGALVQPGGSLRLSCAASGFPVNRYSMRWYRQAPGKEREWVAGMSSAGDRSSYEDSVKGRFTISRDDARNTVYLQM
NSLKPEDTAVYYCNVNVGFEYWGQGTQVTVS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;VSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKLICTTGKLPVPWPTLVTTLGYGLQCFARYPDHMKQ
HDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYITADKQKNG
IKANFKIRHNIEDGGVQLADHYQQNTPIGDGPVLLPDNHYLSYQSKLSKDPNEKRDHMVLLEFVTAAGITTPGWLSREQV
FVLISAASVNLGSMMCYSILGPFFPKEAEKKGASNTIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVT
ILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAFPNNVATVLGSLETFSGLGLILGPPVGGFLYQSFGY
EVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPKVGLIAFVINSLSSCFGFLDPTLSLFVLEKFNLPAGYVG
LVFLGMALSYAISSPLFGLLSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGLSAGMSIIPTF
PEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGLWALISGLAMGLFYLLEYSQVQ
LVESGGALVQPGGSLRLSCAASGFPVNRYSMRWYRQAPGKEREWVAGMSSAGDRSSYEDSVKGRFTISRDDARNTVYLQM
NSLKPEDTAVYYCNVNVGFEYWGQGTQVTVS
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 SPERMIDINE SPD 
3 water      HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   VAL n 
1 2   SER n 
1 3   LYS n 
1 4   GLY n 
1 5   GLU n 
1 6   GLU n 
1 7   LEU n 
1 8   PHE n 
1 9   THR n 
1 10  GLY n 
1 11  VAL n 
1 12  VAL n 
1 13  PRO n 
1 14  ILE n 
1 15  LEU n 
1 16  VAL n 
1 17  GLU n 
1 18  LEU n 
1 19  ASP n 
1 20  GLY n 
1 21  ASP n 
1 22  VAL n 
1 23  ASN n 
1 24  GLY n 
1 25  HIS n 
1 26  LYS n 
1 27  PHE n 
1 28  SER n 
1 29  VAL n 
1 30  SER n 
1 31  GLY n 
1 32  GLU n 
1 33  GLY n 
1 34  GLU n 
1 35  GLY n 
1 36  ASP n 
1 37  ALA n 
1 38  THR n 
1 39  TYR n 
1 40  GLY n 
1 41  LYS n 
1 42  LEU n 
1 43  THR n 
1 44  LEU n 
1 45  LYS n 
1 46  LEU n 
1 47  ILE n 
1 48  CYS n 
1 49  THR n 
1 50  THR n 
1 51  GLY n 
1 52  LYS n 
1 53  LEU n 
1 54  PRO n 
1 55  VAL n 
1 56  PRO n 
1 57  TRP n 
1 58  PRO n 
1 59  THR n 
1 60  LEU n 
1 61  VAL n 
1 62  THR n 
1 63  THR n 
1 64  LEU n 
1 65  GLY n 
1 66  TYR n 
1 67  GLY n 
1 68  LEU n 
1 69  GLN n 
1 70  CYS n 
1 71  PHE n 
1 72  ALA n 
1 73  ARG n 
1 74  TYR n 
1 75  PRO n 
1 76  ASP n 
1 77  HIS n 
1 78  MET n 
1 79  LYS n 
1 80  GLN n 
1 81  HIS n 
1 82  ASP n 
1 83  PHE n 
1 84  PHE n 
1 85  LYS n 
1 86  SER n 
1 87  ALA n 
1 88  MET n 
1 89  PRO n 
1 90  GLU n 
1 91  GLY n 
1 92  TYR n 
1 93  VAL n 
1 94  GLN n 
1 95  GLU n 
1 96  ARG n 
1 97  THR n 
1 98  ILE n 
1 99  PHE n 
1 100 PHE n 
1 101 LYS n 
1 102 ASP n 
1 103 ASP n 
1 104 GLY n 
1 105 ASN n 
1 106 TYR n 
1 107 LYS n 
1 108 THR n 
1 109 ARG n 
1 110 ALA n 
1 111 GLU n 
1 112 VAL n 
1 113 LYS n 
1 114 PHE n 
1 115 GLU n 
1 116 GLY n 
1 117 ASP n 
1 118 THR n 
1 119 LEU n 
1 120 VAL n 
1 121 ASN n 
1 122 ARG n 
1 123 ILE n 
1 124 GLU n 
1 125 LEU n 
1 126 LYS n 
1 127 GLY n 
1 128 ILE n 
1 129 ASP n 
1 130 PHE n 
1 131 LYS n 
1 132 GLU n 
1 133 ASP n 
1 134 GLY n 
1 135 ASN n 
1 136 ILE n 
1 137 LEU n 
1 138 GLY n 
1 139 HIS n 
1 140 LYS n 
1 141 LEU n 
1 142 GLU n 
1 143 TYR n 
1 144 ASN n 
1 145 TYR n 
1 146 ASN n 
1 147 SER n 
1 148 HIS n 
1 149 ASN n 
1 150 VAL n 
1 151 TYR n 
1 152 ILE n 
1 153 THR n 
1 154 ALA n 
1 155 ASP n 
1 156 LYS n 
1 157 GLN n 
1 158 LYS n 
1 159 ASN n 
1 160 GLY n 
1 161 ILE n 
1 162 LYS n 
1 163 ALA n 
1 164 ASN n 
1 165 PHE n 
1 166 LYS n 
1 167 ILE n 
1 168 ARG n 
1 169 HIS n 
1 170 ASN n 
1 171 ILE n 
1 172 GLU n 
1 173 ASP n 
1 174 GLY n 
1 175 GLY n 
1 176 VAL n 
1 177 GLN n 
1 178 LEU n 
1 179 ALA n 
1 180 ASP n 
1 181 HIS n 
1 182 TYR n 
1 183 GLN n 
1 184 GLN n 
1 185 ASN n 
1 186 THR n 
1 187 PRO n 
1 188 ILE n 
1 189 GLY n 
1 190 ASP n 
1 191 GLY n 
1 192 PRO n 
1 193 VAL n 
1 194 LEU n 
1 195 LEU n 
1 196 PRO n 
1 197 ASP n 
1 198 ASN n 
1 199 HIS n 
1 200 TYR n 
1 201 LEU n 
1 202 SER n 
1 203 TYR n 
1 204 GLN n 
1 205 SER n 
1 206 LYS n 
1 207 LEU n 
1 208 SER n 
1 209 LYS n 
1 210 ASP n 
1 211 PRO n 
1 212 ASN n 
1 213 GLU n 
1 214 LYS n 
1 215 ARG n 
1 216 ASP n 
1 217 HIS n 
1 218 MET n 
1 219 VAL n 
1 220 LEU n 
1 221 LEU n 
1 222 GLU n 
1 223 PHE n 
1 224 VAL n 
1 225 THR n 
1 226 ALA n 
1 227 ALA n 
1 228 GLY n 
1 229 ILE n 
1 230 THR n 
1 231 THR n 
1 232 PRO n 
1 233 GLY n 
1 234 TRP n 
1 235 LEU n 
1 236 SER n 
1 237 ARG n 
1 238 GLU n 
1 239 GLN n 
1 240 VAL n 
1 241 PHE n 
1 242 VAL n 
1 243 LEU n 
1 244 ILE n 
1 245 SER n 
1 246 ALA n 
1 247 ALA n 
1 248 SER n 
1 249 VAL n 
1 250 ASN n 
1 251 LEU n 
1 252 GLY n 
1 253 SER n 
1 254 MET n 
1 255 MET n 
1 256 CYS n 
1 257 TYR n 
1 258 SER n 
1 259 ILE n 
1 260 LEU n 
1 261 GLY n 
1 262 PRO n 
1 263 PHE n 
1 264 PHE n 
1 265 PRO n 
1 266 LYS n 
1 267 GLU n 
1 268 ALA n 
1 269 GLU n 
1 270 LYS n 
1 271 LYS n 
1 272 GLY n 
1 273 ALA n 
1 274 SER n 
1 275 ASN n 
1 276 THR n 
1 277 ILE n 
1 278 ILE n 
1 279 GLY n 
1 280 MET n 
1 281 ILE n 
1 282 PHE n 
1 283 GLY n 
1 284 CYS n 
1 285 PHE n 
1 286 ALA n 
1 287 LEU n 
1 288 PHE n 
1 289 GLU n 
1 290 LEU n 
1 291 LEU n 
1 292 ALA n 
1 293 SER n 
1 294 LEU n 
1 295 VAL n 
1 296 PHE n 
1 297 GLY n 
1 298 ASN n 
1 299 TYR n 
1 300 LEU n 
1 301 VAL n 
1 302 HIS n 
1 303 ILE n 
1 304 GLY n 
1 305 ALA n 
1 306 LYS n 
1 307 PHE n 
1 308 MET n 
1 309 PHE n 
1 310 VAL n 
1 311 ALA n 
1 312 GLY n 
1 313 MET n 
1 314 PHE n 
1 315 VAL n 
1 316 SER n 
1 317 GLY n 
1 318 GLY n 
1 319 VAL n 
1 320 THR n 
1 321 ILE n 
1 322 LEU n 
1 323 PHE n 
1 324 GLY n 
1 325 VAL n 
1 326 LEU n 
1 327 ASP n 
1 328 ARG n 
1 329 VAL n 
1 330 PRO n 
1 331 ASP n 
1 332 GLY n 
1 333 PRO n 
1 334 VAL n 
1 335 PHE n 
1 336 ILE n 
1 337 ALA n 
1 338 MET n 
1 339 CYS n 
1 340 PHE n 
1 341 LEU n 
1 342 VAL n 
1 343 ARG n 
1 344 VAL n 
1 345 MET n 
1 346 ASP n 
1 347 ALA n 
1 348 VAL n 
1 349 SER n 
1 350 PHE n 
1 351 ALA n 
1 352 ALA n 
1 353 ALA n 
1 354 MET n 
1 355 THR n 
1 356 ALA n 
1 357 SER n 
1 358 SER n 
1 359 SER n 
1 360 ILE n 
1 361 LEU n 
1 362 ALA n 
1 363 LYS n 
1 364 ALA n 
1 365 PHE n 
1 366 PRO n 
1 367 ASN n 
1 368 ASN n 
1 369 VAL n 
1 370 ALA n 
1 371 THR n 
1 372 VAL n 
1 373 LEU n 
1 374 GLY n 
1 375 SER n 
1 376 LEU n 
1 377 GLU n 
1 378 THR n 
1 379 PHE n 
1 380 SER n 
1 381 GLY n 
1 382 LEU n 
1 383 GLY n 
1 384 LEU n 
1 385 ILE n 
1 386 LEU n 
1 387 GLY n 
1 388 PRO n 
1 389 PRO n 
1 390 VAL n 
1 391 GLY n 
1 392 GLY n 
1 393 PHE n 
1 394 LEU n 
1 395 TYR n 
1 396 GLN n 
1 397 SER n 
1 398 PHE n 
1 399 GLY n 
1 400 TYR n 
1 401 GLU n 
1 402 VAL n 
1 403 PRO n 
1 404 PHE n 
1 405 ILE n 
1 406 VAL n 
1 407 LEU n 
1 408 GLY n 
1 409 CYS n 
1 410 VAL n 
1 411 VAL n 
1 412 LEU n 
1 413 LEU n 
1 414 MET n 
1 415 VAL n 
1 416 PRO n 
1 417 LEU n 
1 418 ASN n 
1 419 MET n 
1 420 TYR n 
1 421 ILE n 
1 422 LEU n 
1 423 PRO n 
1 424 ASN n 
1 425 TYR n 
1 426 GLU n 
1 427 SER n 
1 428 ASP n 
1 429 PRO n 
1 430 GLY n 
1 431 GLU n 
1 432 HIS n 
1 433 SER n 
1 434 PHE n 
1 435 TRP n 
1 436 LYS n 
1 437 LEU n 
1 438 ILE n 
1 439 ALA n 
1 440 LEU n 
1 441 PRO n 
1 442 LYS n 
1 443 VAL n 
1 444 GLY n 
1 445 LEU n 
1 446 ILE n 
1 447 ALA n 
1 448 PHE n 
1 449 VAL n 
1 450 ILE n 
1 451 ASN n 
1 452 SER n 
1 453 LEU n 
1 454 SER n 
1 455 SER n 
1 456 CYS n 
1 457 PHE n 
1 458 GLY n 
1 459 PHE n 
1 460 LEU n 
1 461 ASP n 
1 462 PRO n 
1 463 THR n 
1 464 LEU n 
1 465 SER n 
1 466 LEU n 
1 467 PHE n 
1 468 VAL n 
1 469 LEU n 
1 470 GLU n 
1 471 LYS n 
1 472 PHE n 
1 473 ASN n 
1 474 LEU n 
1 475 PRO n 
1 476 ALA n 
1 477 GLY n 
1 478 TYR n 
1 479 VAL n 
1 480 GLY n 
1 481 LEU n 
1 482 VAL n 
1 483 PHE n 
1 484 LEU n 
1 485 GLY n 
1 486 MET n 
1 487 ALA n 
1 488 LEU n 
1 489 SER n 
1 490 TYR n 
1 491 ALA n 
1 492 ILE n 
1 493 SER n 
1 494 SER n 
1 495 PRO n 
1 496 LEU n 
1 497 PHE n 
1 498 GLY n 
1 499 LEU n 
1 500 LEU n 
1 501 SER n 
1 502 ASP n 
1 503 LYS n 
1 504 ARG n 
1 505 PRO n 
1 506 PRO n 
1 507 LEU n 
1 508 ARG n 
1 509 LYS n 
1 510 TRP n 
1 511 LEU n 
1 512 LEU n 
1 513 VAL n 
1 514 PHE n 
1 515 GLY n 
1 516 ASN n 
1 517 LEU n 
1 518 ILE n 
1 519 THR n 
1 520 ALA n 
1 521 GLY n 
1 522 CYS n 
1 523 TYR n 
1 524 MET n 
1 525 LEU n 
1 526 LEU n 
1 527 GLY n 
1 528 PRO n 
1 529 VAL n 
1 530 PRO n 
1 531 ILE n 
1 532 LEU n 
1 533 HIS n 
1 534 ILE n 
1 535 LYS n 
1 536 SER n 
1 537 GLN n 
1 538 LEU n 
1 539 TRP n 
1 540 LEU n 
1 541 LEU n 
1 542 VAL n 
1 543 LEU n 
1 544 ILE n 
1 545 LEU n 
1 546 VAL n 
1 547 VAL n 
1 548 SER n 
1 549 GLY n 
1 550 LEU n 
1 551 SER n 
1 552 ALA n 
1 553 GLY n 
1 554 MET n 
1 555 SER n 
1 556 ILE n 
1 557 ILE n 
1 558 PRO n 
1 559 THR n 
1 560 PHE n 
1 561 PRO n 
1 562 GLU n 
1 563 ILE n 
1 564 LEU n 
1 565 SER n 
1 566 CYS n 
1 567 ALA n 
1 568 HIS n 
1 569 GLU n 
1 570 ASN n 
1 571 GLY n 
1 572 PHE n 
1 573 GLU n 
1 574 GLU n 
1 575 GLY n 
1 576 LEU n 
1 577 SER n 
1 578 THR n 
1 579 LEU n 
1 580 GLY n 
1 581 LEU n 
1 582 VAL n 
1 583 SER n 
1 584 GLY n 
1 585 LEU n 
1 586 PHE n 
1 587 SER n 
1 588 ALA n 
1 589 MET n 
1 590 TRP n 
1 591 SER n 
1 592 ILE n 
1 593 GLY n 
1 594 ALA n 
1 595 PHE n 
1 596 MET n 
1 597 GLY n 
1 598 PRO n 
1 599 THR n 
1 600 LEU n 
1 601 GLY n 
1 602 GLY n 
1 603 PHE n 
1 604 LEU n 
1 605 TYR n 
1 606 GLU n 
1 607 LYS n 
1 608 ILE n 
1 609 GLY n 
1 610 PHE n 
1 611 GLU n 
1 612 TRP n 
1 613 ALA n 
1 614 ALA n 
1 615 ALA n 
1 616 ILE n 
1 617 GLN n 
1 618 GLY n 
1 619 LEU n 
1 620 TRP n 
1 621 ALA n 
1 622 LEU n 
1 623 ILE n 
1 624 SER n 
1 625 GLY n 
1 626 LEU n 
1 627 ALA n 
1 628 MET n 
1 629 GLY n 
1 630 LEU n 
1 631 PHE n 
1 632 TYR n 
1 633 LEU n 
1 634 LEU n 
1 635 GLU n 
1 636 TYR n 
1 637 SER n 
1 638 GLN n 
1 639 VAL n 
1 640 GLN n 
1 641 LEU n 
1 642 VAL n 
1 643 GLU n 
1 644 SER n 
1 645 GLY n 
1 646 GLY n 
1 647 ALA n 
1 648 LEU n 
1 649 VAL n 
1 650 GLN n 
1 651 PRO n 
1 652 GLY n 
1 653 GLY n 
1 654 SER n 
1 655 LEU n 
1 656 ARG n 
1 657 LEU n 
1 658 SER n 
1 659 CYS n 
1 660 ALA n 
1 661 ALA n 
1 662 SER n 
1 663 GLY n 
1 664 PHE n 
1 665 PRO n 
1 666 VAL n 
1 667 ASN n 
1 668 ARG n 
1 669 TYR n 
1 670 SER n 
1 671 MET n 
1 672 ARG n 
1 673 TRP n 
1 674 TYR n 
1 675 ARG n 
1 676 GLN n 
1 677 ALA n 
1 678 PRO n 
1 679 GLY n 
1 680 LYS n 
1 681 GLU n 
1 682 ARG n 
1 683 GLU n 
1 684 TRP n 
1 685 VAL n 
1 686 ALA n 
1 687 GLY n 
1 688 MET n 
1 689 SER n 
1 690 SER n 
1 691 ALA n 
1 692 GLY n 
1 693 ASP n 
1 694 ARG n 
1 695 SER n 
1 696 SER n 
1 697 TYR n 
1 698 GLU n 
1 699 ASP n 
1 700 SER n 
1 701 VAL n 
1 702 LYS n 
1 703 GLY n 
1 704 ARG n 
1 705 PHE n 
1 706 THR n 
1 707 ILE n 
1 708 SER n 
1 709 ARG n 
1 710 ASP n 
1 711 ASP n 
1 712 ALA n 
1 713 ARG n 
1 714 ASN n 
1 715 THR n 
1 716 VAL n 
1 717 TYR n 
1 718 LEU n 
1 719 GLN n 
1 720 MET n 
1 721 ASN n 
1 722 SER n 
1 723 LEU n 
1 724 LYS n 
1 725 PRO n 
1 726 GLU n 
1 727 ASP n 
1 728 THR n 
1 729 ALA n 
1 730 VAL n 
1 731 TYR n 
1 732 TYR n 
1 733 CYS n 
1 734 ASN n 
1 735 VAL n 
1 736 ASN n 
1 737 VAL n 
1 738 GLY n 
1 739 PHE n 
1 740 GLU n 
1 741 TYR n 
1 742 TRP n 
1 743 GLY n 
1 744 GLN n 
1 745 GLY n 
1 746 THR n 
1 747 GLN n 
1 748 VAL n 
1 749 THR n 
1 750 VAL n 
1 751 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   230 human ? APY04_3197          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Insect cell expression vector pTIE1' 266783 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 231 637 human ? 'SLC18B1, C6orf192' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Insect cell expression vector pTIE1' 266783 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 638 751 ?     ? ?                   ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Insect cell expression vector pTIE1' 266783 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                                              'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                                              'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                                              'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                              'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                                              'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ?                                              'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                              'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                                              'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ?                                              'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                                              'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                                              'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                                              'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                                              'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                                              'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                                              'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                                              'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                                              'C3 H7 N O3'     105.093 
SPD non-polymer         . SPERMIDINE      'N-(2-AMINO-PROPYL)-1,4-DIAMINOBUTANE; PA(34)' 'C7 H19 N3'      145.246 
THR 'L-peptide linking' y THREONINE       ?                                              'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                                              'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                                              'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                                              'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   VAL 1   2   2   VAL VAL A . n 
A 1 2   SER 2   3   3   SER SER A . n 
A 1 3   LYS 3   4   4   LYS LYS A . n 
A 1 4   GLY 4   5   5   GLY GLY A . n 
A 1 5   GLU 5   6   6   GLU GLU A . n 
A 1 6   GLU 6   7   7   GLU GLU A . n 
A 1 7   LEU 7   8   8   LEU LEU A . n 
A 1 8   PHE 8   9   9   PHE PHE A . n 
A 1 9   THR 9   10  10  THR THR A . n 
A 1 10  GLY 10  11  11  GLY GLY A . n 
A 1 11  VAL 11  12  12  VAL VAL A . n 
A 1 12  VAL 12  13  13  VAL VAL A . n 
A 1 13  PRO 13  14  14  PRO PRO A . n 
A 1 14  ILE 14  15  15  ILE ILE A . n 
A 1 15  LEU 15  16  16  LEU LEU A . n 
A 1 16  VAL 16  17  17  VAL VAL A . n 
A 1 17  GLU 17  18  18  GLU GLU A . n 
A 1 18  LEU 18  19  19  LEU LEU A . n 
A 1 19  ASP 19  20  20  ASP ASP A . n 
A 1 20  GLY 20  21  21  GLY GLY A . n 
A 1 21  ASP 21  22  22  ASP ASP A . n 
A 1 22  VAL 22  23  23  VAL VAL A . n 
A 1 23  ASN 23  24  24  ASN ASN A . n 
A 1 24  GLY 24  25  25  GLY GLY A . n 
A 1 25  HIS 25  26  26  HIS HIS A . n 
A 1 26  LYS 26  27  27  LYS LYS A . n 
A 1 27  PHE 27  28  28  PHE PHE A . n 
A 1 28  SER 28  29  29  SER SER A . n 
A 1 29  VAL 29  30  30  VAL VAL A . n 
A 1 30  SER 30  31  31  SER SER A . n 
A 1 31  GLY 31  32  32  GLY GLY A . n 
A 1 32  GLU 32  33  33  GLU GLU A . n 
A 1 33  GLY 33  34  34  GLY GLY A . n 
A 1 34  GLU 34  35  35  GLU GLU A . n 
A 1 35  GLY 35  36  36  GLY GLY A . n 
A 1 36  ASP 36  37  37  ASP ASP A . n 
A 1 37  ALA 37  38  38  ALA ALA A . n 
A 1 38  THR 38  39  39  THR THR A . n 
A 1 39  TYR 39  40  40  TYR TYR A . n 
A 1 40  GLY 40  41  41  GLY GLY A . n 
A 1 41  LYS 41  42  42  LYS LYS A . n 
A 1 42  LEU 42  43  43  LEU LEU A . n 
A 1 43  THR 43  44  44  THR THR A . n 
A 1 44  LEU 44  45  45  LEU LEU A . n 
A 1 45  LYS 45  46  46  LYS LYS A . n 
A 1 46  LEU 46  47  47  LEU LEU A . n 
A 1 47  ILE 47  48  48  ILE ILE A . n 
A 1 48  CYS 48  49  49  CYS CYS A . n 
A 1 49  THR 49  50  50  THR THR A . n 
A 1 50  THR 50  51  51  THR THR A . n 
A 1 51  GLY 51  52  52  GLY GLY A . n 
A 1 52  LYS 52  53  53  LYS LYS A . n 
A 1 53  LEU 53  54  54  LEU LEU A . n 
A 1 54  PRO 54  55  55  PRO PRO A . n 
A 1 55  VAL 55  56  56  VAL VAL A . n 
A 1 56  PRO 56  57  57  PRO PRO A . n 
A 1 57  TRP 57  58  58  TRP TRP A . n 
A 1 58  PRO 58  59  59  PRO PRO A . n 
A 1 59  THR 59  60  60  THR THR A . n 
A 1 60  LEU 60  61  61  LEU LEU A . n 
A 1 61  VAL 61  62  62  VAL VAL A . n 
A 1 62  THR 62  63  63  THR THR A . n 
A 1 63  THR 63  64  64  THR THR A . n 
A 1 64  LEU 64  65  65  LEU LEU A . n 
A 1 65  GLY 65  66  66  GLY GLY A . n 
A 1 66  TYR 66  67  67  TYR TYR A . n 
A 1 67  GLY 67  68  68  GLY GLY A . n 
A 1 68  LEU 68  69  69  LEU LEU A . n 
A 1 69  GLN 69  70  70  GLN GLN A . n 
A 1 70  CYS 70  71  71  CYS CYS A . n 
A 1 71  PHE 71  72  72  PHE PHE A . n 
A 1 72  ALA 72  73  73  ALA ALA A . n 
A 1 73  ARG 73  74  74  ARG ARG A . n 
A 1 74  TYR 74  75  75  TYR TYR A . n 
A 1 75  PRO 75  76  76  PRO PRO A . n 
A 1 76  ASP 76  77  77  ASP ASP A . n 
A 1 77  HIS 77  78  78  HIS HIS A . n 
A 1 78  MET 78  79  79  MET MET A . n 
A 1 79  LYS 79  80  80  LYS LYS A . n 
A 1 80  GLN 80  81  81  GLN GLN A . n 
A 1 81  HIS 81  82  82  HIS HIS A . n 
A 1 82  ASP 82  83  83  ASP ASP A . n 
A 1 83  PHE 83  84  84  PHE PHE A . n 
A 1 84  PHE 84  85  85  PHE PHE A . n 
A 1 85  LYS 85  86  86  LYS LYS A . n 
A 1 86  SER 86  87  87  SER SER A . n 
A 1 87  ALA 87  88  88  ALA ALA A . n 
A 1 88  MET 88  89  89  MET MET A . n 
A 1 89  PRO 89  90  90  PRO PRO A . n 
A 1 90  GLU 90  91  91  GLU GLU A . n 
A 1 91  GLY 91  92  92  GLY GLY A . n 
A 1 92  TYR 92  93  93  TYR TYR A . n 
A 1 93  VAL 93  94  94  VAL VAL A . n 
A 1 94  GLN 94  95  95  GLN GLN A . n 
A 1 95  GLU 95  96  96  GLU GLU A . n 
A 1 96  ARG 96  97  97  ARG ARG A . n 
A 1 97  THR 97  98  98  THR THR A . n 
A 1 98  ILE 98  99  99  ILE ILE A . n 
A 1 99  PHE 99  100 100 PHE PHE A . n 
A 1 100 PHE 100 101 101 PHE PHE A . n 
A 1 101 LYS 101 102 102 LYS LYS A . n 
A 1 102 ASP 102 103 103 ASP ASP A . n 
A 1 103 ASP 103 104 104 ASP ASP A . n 
A 1 104 GLY 104 105 105 GLY GLY A . n 
A 1 105 ASN 105 106 106 ASN ASN A . n 
A 1 106 TYR 106 107 107 TYR TYR A . n 
A 1 107 LYS 107 108 108 LYS LYS A . n 
A 1 108 THR 108 109 109 THR THR A . n 
A 1 109 ARG 109 110 110 ARG ARG A . n 
A 1 110 ALA 110 111 111 ALA ALA A . n 
A 1 111 GLU 111 112 112 GLU GLU A . n 
A 1 112 VAL 112 113 113 VAL VAL A . n 
A 1 113 LYS 113 114 114 LYS LYS A . n 
A 1 114 PHE 114 115 115 PHE PHE A . n 
A 1 115 GLU 115 116 116 GLU GLU A . n 
A 1 116 GLY 116 117 117 GLY GLY A . n 
A 1 117 ASP 117 118 118 ASP ASP A . n 
A 1 118 THR 118 119 119 THR THR A . n 
A 1 119 LEU 119 120 120 LEU LEU A . n 
A 1 120 VAL 120 121 121 VAL VAL A . n 
A 1 121 ASN 121 122 122 ASN ASN A . n 
A 1 122 ARG 122 123 123 ARG ARG A . n 
A 1 123 ILE 123 124 124 ILE ILE A . n 
A 1 124 GLU 124 125 125 GLU GLU A . n 
A 1 125 LEU 125 126 126 LEU LEU A . n 
A 1 126 LYS 126 127 127 LYS LYS A . n 
A 1 127 GLY 127 128 128 GLY GLY A . n 
A 1 128 ILE 128 129 129 ILE ILE A . n 
A 1 129 ASP 129 130 130 ASP ASP A . n 
A 1 130 PHE 130 131 131 PHE PHE A . n 
A 1 131 LYS 131 132 132 LYS LYS A . n 
A 1 132 GLU 132 133 133 GLU GLU A . n 
A 1 133 ASP 133 134 134 ASP ASP A . n 
A 1 134 GLY 134 135 135 GLY GLY A . n 
A 1 135 ASN 135 136 136 ASN ASN A . n 
A 1 136 ILE 136 137 137 ILE ILE A . n 
A 1 137 LEU 137 138 138 LEU LEU A . n 
A 1 138 GLY 138 139 139 GLY GLY A . n 
A 1 139 HIS 139 140 140 HIS HIS A . n 
A 1 140 LYS 140 141 141 LYS LYS A . n 
A 1 141 LEU 141 142 142 LEU LEU A . n 
A 1 142 GLU 142 143 143 GLU GLU A . n 
A 1 143 TYR 143 144 144 TYR TYR A . n 
A 1 144 ASN 144 145 145 ASN ASN A . n 
A 1 145 TYR 145 146 146 TYR TYR A . n 
A 1 146 ASN 146 147 147 ASN ASN A . n 
A 1 147 SER 147 148 148 SER SER A . n 
A 1 148 HIS 148 149 149 HIS HIS A . n 
A 1 149 ASN 149 150 150 ASN ASN A . n 
A 1 150 VAL 150 151 151 VAL VAL A . n 
A 1 151 TYR 151 152 152 TYR TYR A . n 
A 1 152 ILE 152 153 153 ILE ILE A . n 
A 1 153 THR 153 154 154 THR THR A . n 
A 1 154 ALA 154 155 155 ALA ALA A . n 
A 1 155 ASP 155 156 156 ASP ASP A . n 
A 1 156 LYS 156 157 157 LYS LYS A . n 
A 1 157 GLN 157 158 158 GLN GLN A . n 
A 1 158 LYS 158 159 159 LYS LYS A . n 
A 1 159 ASN 159 160 160 ASN ASN A . n 
A 1 160 GLY 160 161 161 GLY GLY A . n 
A 1 161 ILE 161 162 162 ILE ILE A . n 
A 1 162 LYS 162 163 163 LYS LYS A . n 
A 1 163 ALA 163 164 164 ALA ALA A . n 
A 1 164 ASN 164 165 165 ASN ASN A . n 
A 1 165 PHE 165 166 166 PHE PHE A . n 
A 1 166 LYS 166 167 167 LYS LYS A . n 
A 1 167 ILE 167 168 168 ILE ILE A . n 
A 1 168 ARG 168 169 169 ARG ARG A . n 
A 1 169 HIS 169 170 170 HIS HIS A . n 
A 1 170 ASN 170 171 171 ASN ASN A . n 
A 1 171 ILE 171 172 172 ILE ILE A . n 
A 1 172 GLU 172 173 173 GLU GLU A . n 
A 1 173 ASP 173 174 174 ASP ASP A . n 
A 1 174 GLY 174 175 175 GLY GLY A . n 
A 1 175 GLY 175 176 176 GLY GLY A . n 
A 1 176 VAL 176 177 177 VAL VAL A . n 
A 1 177 GLN 177 178 178 GLN GLN A . n 
A 1 178 LEU 178 179 179 LEU LEU A . n 
A 1 179 ALA 179 180 180 ALA ALA A . n 
A 1 180 ASP 180 181 181 ASP ASP A . n 
A 1 181 HIS 181 182 182 HIS HIS A . n 
A 1 182 TYR 182 183 183 TYR TYR A . n 
A 1 183 GLN 183 184 184 GLN GLN A . n 
A 1 184 GLN 184 185 185 GLN GLN A . n 
A 1 185 ASN 185 186 186 ASN ASN A . n 
A 1 186 THR 186 187 187 THR THR A . n 
A 1 187 PRO 187 188 188 PRO PRO A . n 
A 1 188 ILE 188 189 189 ILE ILE A . n 
A 1 189 GLY 189 190 190 GLY GLY A . n 
A 1 190 ASP 190 191 191 ASP ASP A . n 
A 1 191 GLY 191 192 192 GLY GLY A . n 
A 1 192 PRO 192 193 193 PRO PRO A . n 
A 1 193 VAL 193 194 194 VAL VAL A . n 
A 1 194 LEU 194 195 195 LEU LEU A . n 
A 1 195 LEU 195 196 196 LEU LEU A . n 
A 1 196 PRO 196 197 197 PRO PRO A . n 
A 1 197 ASP 197 198 198 ASP ASP A . n 
A 1 198 ASN 198 199 199 ASN ASN A . n 
A 1 199 HIS 199 200 200 HIS HIS A . n 
A 1 200 TYR 200 201 201 TYR TYR A . n 
A 1 201 LEU 201 202 202 LEU LEU A . n 
A 1 202 SER 202 203 203 SER SER A . n 
A 1 203 TYR 203 204 204 TYR TYR A . n 
A 1 204 GLN 204 205 205 GLN GLN A . n 
A 1 205 SER 205 206 206 SER SER A . n 
A 1 206 LYS 206 207 207 LYS LYS A . n 
A 1 207 LEU 207 208 208 LEU LEU A . n 
A 1 208 SER 208 209 209 SER SER A . n 
A 1 209 LYS 209 210 210 LYS LYS A . n 
A 1 210 ASP 210 211 211 ASP ASP A . n 
A 1 211 PRO 211 212 212 PRO PRO A . n 
A 1 212 ASN 212 213 213 ASN ASN A . n 
A 1 213 GLU 213 214 214 GLU GLU A . n 
A 1 214 LYS 214 215 215 LYS LYS A . n 
A 1 215 ARG 215 216 216 ARG ARG A . n 
A 1 216 ASP 216 217 217 ASP ASP A . n 
A 1 217 HIS 217 218 218 HIS HIS A . n 
A 1 218 MET 218 219 219 MET MET A . n 
A 1 219 VAL 219 220 220 VAL VAL A . n 
A 1 220 LEU 220 221 221 LEU LEU A . n 
A 1 221 LEU 221 222 222 LEU LEU A . n 
A 1 222 GLU 222 223 223 GLU GLU A . n 
A 1 223 PHE 223 224 224 PHE PHE A . n 
A 1 224 VAL 224 225 225 VAL VAL A . n 
A 1 225 THR 225 226 226 THR THR A . n 
A 1 226 ALA 226 227 227 ALA ALA A . n 
A 1 227 ALA 227 228 228 ALA ALA A . n 
A 1 228 GLY 228 229 229 GLY GLY A . n 
A 1 229 ILE 229 230 230 ILE ILE A . n 
A 1 230 THR 230 231 231 THR THR A . n 
A 1 231 THR 231 232 232 THR THR A . n 
A 1 232 PRO 232 233 233 PRO PRO A . n 
A 1 233 GLY 233 234 234 GLY GLY A . n 
A 1 234 TRP 234 235 235 TRP TRP A . n 
A 1 235 LEU 235 236 236 LEU LEU A . n 
A 1 236 SER 236 237 237 SER SER A . n 
A 1 237 ARG 237 238 238 ARG ARG A . n 
A 1 238 GLU 238 239 239 GLU GLU A . n 
A 1 239 GLN 239 240 240 GLN GLN A . n 
A 1 240 VAL 240 241 241 VAL VAL A . n 
A 1 241 PHE 241 242 242 PHE PHE A . n 
A 1 242 VAL 242 243 243 VAL VAL A . n 
A 1 243 LEU 243 244 244 LEU LEU A . n 
A 1 244 ILE 244 245 245 ILE ILE A . n 
A 1 245 SER 245 246 246 SER SER A . n 
A 1 246 ALA 246 247 247 ALA ALA A . n 
A 1 247 ALA 247 248 248 ALA ALA A . n 
A 1 248 SER 248 249 249 SER SER A . n 
A 1 249 VAL 249 250 250 VAL VAL A . n 
A 1 250 ASN 250 251 251 ASN ASN A . n 
A 1 251 LEU 251 252 252 LEU LEU A . n 
A 1 252 GLY 252 253 253 GLY GLY A . n 
A 1 253 SER 253 254 254 SER SER A . n 
A 1 254 MET 254 255 255 MET MET A . n 
A 1 255 MET 255 256 256 MET MET A . n 
A 1 256 CYS 256 257 257 CYS CYS A . n 
A 1 257 TYR 257 258 258 TYR TYR A . n 
A 1 258 SER 258 259 259 SER SER A . n 
A 1 259 ILE 259 260 260 ILE ILE A . n 
A 1 260 LEU 260 261 261 LEU LEU A . n 
A 1 261 GLY 261 262 262 GLY GLY A . n 
A 1 262 PRO 262 263 ?   ?   ?   A . n 
A 1 263 PHE 263 264 ?   ?   ?   A . n 
A 1 264 PHE 264 265 ?   ?   ?   A . n 
A 1 265 PRO 265 266 ?   ?   ?   A . n 
A 1 266 LYS 266 267 ?   ?   ?   A . n 
A 1 267 GLU 267 268 ?   ?   ?   A . n 
A 1 268 ALA 268 269 ?   ?   ?   A . n 
A 1 269 GLU 269 270 ?   ?   ?   A . n 
A 1 270 LYS 270 271 ?   ?   ?   A . n 
A 1 271 LYS 271 272 ?   ?   ?   A . n 
A 1 272 GLY 272 273 ?   ?   ?   A . n 
A 1 273 ALA 273 274 ?   ?   ?   A . n 
A 1 274 SER 274 275 ?   ?   ?   A . n 
A 1 275 ASN 275 276 ?   ?   ?   A . n 
A 1 276 THR 276 277 ?   ?   ?   A . n 
A 1 277 ILE 277 278 ?   ?   ?   A . n 
A 1 278 ILE 278 279 ?   ?   ?   A . n 
A 1 279 GLY 279 280 280 GLY GLY A . n 
A 1 280 MET 280 281 281 MET MET A . n 
A 1 281 ILE 281 282 282 ILE ILE A . n 
A 1 282 PHE 282 283 283 PHE PHE A . n 
A 1 283 GLY 283 284 284 GLY GLY A . n 
A 1 284 CYS 284 285 285 CYS CYS A . n 
A 1 285 PHE 285 286 286 PHE PHE A . n 
A 1 286 ALA 286 287 287 ALA ALA A . n 
A 1 287 LEU 287 288 288 LEU LEU A . n 
A 1 288 PHE 288 289 289 PHE PHE A . n 
A 1 289 GLU 289 290 290 GLU GLU A . n 
A 1 290 LEU 290 291 291 LEU LEU A . n 
A 1 291 LEU 291 292 292 LEU LEU A . n 
A 1 292 ALA 292 293 293 ALA ALA A . n 
A 1 293 SER 293 294 294 SER SER A . n 
A 1 294 LEU 294 295 295 LEU LEU A . n 
A 1 295 VAL 295 296 296 VAL VAL A . n 
A 1 296 PHE 296 297 297 PHE PHE A . n 
A 1 297 GLY 297 298 298 GLY GLY A . n 
A 1 298 ASN 298 299 299 ASN ASN A . n 
A 1 299 TYR 299 300 300 TYR TYR A . n 
A 1 300 LEU 300 301 301 LEU LEU A . n 
A 1 301 VAL 301 302 302 VAL VAL A . n 
A 1 302 HIS 302 303 303 HIS HIS A . n 
A 1 303 ILE 303 304 304 ILE ILE A . n 
A 1 304 GLY 304 305 305 GLY GLY A . n 
A 1 305 ALA 305 306 306 ALA ALA A . n 
A 1 306 LYS 306 307 307 LYS LYS A . n 
A 1 307 PHE 307 308 308 PHE PHE A . n 
A 1 308 MET 308 309 309 MET MET A . n 
A 1 309 PHE 309 310 310 PHE PHE A . n 
A 1 310 VAL 310 311 311 VAL VAL A . n 
A 1 311 ALA 311 312 312 ALA ALA A . n 
A 1 312 GLY 312 313 313 GLY GLY A . n 
A 1 313 MET 313 314 314 MET MET A . n 
A 1 314 PHE 314 315 315 PHE PHE A . n 
A 1 315 VAL 315 316 316 VAL VAL A . n 
A 1 316 SER 316 317 317 SER SER A . n 
A 1 317 GLY 317 318 318 GLY GLY A . n 
A 1 318 GLY 318 319 319 GLY GLY A . n 
A 1 319 VAL 319 320 320 VAL VAL A . n 
A 1 320 THR 320 321 321 THR THR A . n 
A 1 321 ILE 321 322 322 ILE ILE A . n 
A 1 322 LEU 322 323 323 LEU LEU A . n 
A 1 323 PHE 323 324 324 PHE PHE A . n 
A 1 324 GLY 324 325 325 GLY GLY A . n 
A 1 325 VAL 325 326 326 VAL VAL A . n 
A 1 326 LEU 326 327 327 LEU LEU A . n 
A 1 327 ASP 327 328 328 ASP ASP A . n 
A 1 328 ARG 328 329 329 ARG ARG A . n 
A 1 329 VAL 329 330 330 VAL VAL A . n 
A 1 330 PRO 330 331 331 PRO PRO A . n 
A 1 331 ASP 331 332 332 ASP ASP A . n 
A 1 332 GLY 332 333 333 GLY GLY A . n 
A 1 333 PRO 333 334 334 PRO PRO A . n 
A 1 334 VAL 334 335 335 VAL VAL A . n 
A 1 335 PHE 335 336 336 PHE PHE A . n 
A 1 336 ILE 336 337 337 ILE ILE A . n 
A 1 337 ALA 337 338 338 ALA ALA A . n 
A 1 338 MET 338 339 339 MET MET A . n 
A 1 339 CYS 339 340 340 CYS CYS A . n 
A 1 340 PHE 340 341 341 PHE PHE A . n 
A 1 341 LEU 341 342 342 LEU LEU A . n 
A 1 342 VAL 342 343 343 VAL VAL A . n 
A 1 343 ARG 343 344 344 ARG ARG A . n 
A 1 344 VAL 344 345 345 VAL VAL A . n 
A 1 345 MET 345 346 346 MET MET A . n 
A 1 346 ASP 346 347 347 ASP ASP A . n 
A 1 347 ALA 347 348 348 ALA ALA A . n 
A 1 348 VAL 348 349 349 VAL VAL A . n 
A 1 349 SER 349 350 350 SER SER A . n 
A 1 350 PHE 350 351 351 PHE PHE A . n 
A 1 351 ALA 351 352 352 ALA ALA A . n 
A 1 352 ALA 352 353 353 ALA ALA A . n 
A 1 353 ALA 353 354 354 ALA ALA A . n 
A 1 354 MET 354 355 355 MET MET A . n 
A 1 355 THR 355 356 356 THR THR A . n 
A 1 356 ALA 356 357 357 ALA ALA A . n 
A 1 357 SER 357 358 358 SER SER A . n 
A 1 358 SER 358 359 359 SER SER A . n 
A 1 359 SER 359 360 360 SER SER A . n 
A 1 360 ILE 360 361 361 ILE ILE A . n 
A 1 361 LEU 361 362 362 LEU LEU A . n 
A 1 362 ALA 362 363 363 ALA ALA A . n 
A 1 363 LYS 363 364 364 LYS LYS A . n 
A 1 364 ALA 364 365 365 ALA ALA A . n 
A 1 365 PHE 365 366 366 PHE PHE A . n 
A 1 366 PRO 366 367 367 PRO PRO A . n 
A 1 367 ASN 367 368 368 ASN ASN A . n 
A 1 368 ASN 368 369 369 ASN ASN A . n 
A 1 369 VAL 369 370 370 VAL VAL A . n 
A 1 370 ALA 370 371 371 ALA ALA A . n 
A 1 371 THR 371 372 372 THR THR A . n 
A 1 372 VAL 372 373 373 VAL VAL A . n 
A 1 373 LEU 373 374 374 LEU LEU A . n 
A 1 374 GLY 374 375 375 GLY GLY A . n 
A 1 375 SER 375 376 376 SER SER A . n 
A 1 376 LEU 376 377 377 LEU LEU A . n 
A 1 377 GLU 377 378 378 GLU GLU A . n 
A 1 378 THR 378 379 379 THR THR A . n 
A 1 379 PHE 379 380 380 PHE PHE A . n 
A 1 380 SER 380 381 381 SER SER A . n 
A 1 381 GLY 381 382 382 GLY GLY A . n 
A 1 382 LEU 382 383 383 LEU LEU A . n 
A 1 383 GLY 383 384 384 GLY GLY A . n 
A 1 384 LEU 384 385 385 LEU LEU A . n 
A 1 385 ILE 385 386 386 ILE ILE A . n 
A 1 386 LEU 386 387 387 LEU LEU A . n 
A 1 387 GLY 387 388 388 GLY GLY A . n 
A 1 388 PRO 388 389 389 PRO PRO A . n 
A 1 389 PRO 389 390 390 PRO PRO A . n 
A 1 390 VAL 390 391 391 VAL VAL A . n 
A 1 391 GLY 391 392 392 GLY GLY A . n 
A 1 392 GLY 392 393 393 GLY GLY A . n 
A 1 393 PHE 393 394 394 PHE PHE A . n 
A 1 394 LEU 394 395 395 LEU LEU A . n 
A 1 395 TYR 395 396 396 TYR TYR A . n 
A 1 396 GLN 396 397 397 GLN GLN A . n 
A 1 397 SER 397 398 398 SER SER A . n 
A 1 398 PHE 398 399 399 PHE PHE A . n 
A 1 399 GLY 399 400 400 GLY GLY A . n 
A 1 400 TYR 400 401 401 TYR TYR A . n 
A 1 401 GLU 401 402 402 GLU GLU A . n 
A 1 402 VAL 402 403 403 VAL VAL A . n 
A 1 403 PRO 403 404 404 PRO PRO A . n 
A 1 404 PHE 404 405 405 PHE PHE A . n 
A 1 405 ILE 405 406 406 ILE ILE A . n 
A 1 406 VAL 406 407 407 VAL VAL A . n 
A 1 407 LEU 407 408 408 LEU LEU A . n 
A 1 408 GLY 408 409 409 GLY GLY A . n 
A 1 409 CYS 409 410 410 CYS CYS A . n 
A 1 410 VAL 410 411 411 VAL VAL A . n 
A 1 411 VAL 411 412 412 VAL VAL A . n 
A 1 412 LEU 412 413 413 LEU LEU A . n 
A 1 413 LEU 413 414 414 LEU LEU A . n 
A 1 414 MET 414 415 415 MET MET A . n 
A 1 415 VAL 415 416 416 VAL VAL A . n 
A 1 416 PRO 416 417 417 PRO PRO A . n 
A 1 417 LEU 417 418 418 LEU LEU A . n 
A 1 418 ASN 418 419 419 ASN ASN A . n 
A 1 419 MET 419 420 420 MET MET A . n 
A 1 420 TYR 420 421 421 TYR TYR A . n 
A 1 421 ILE 421 422 422 ILE ILE A . n 
A 1 422 LEU 422 423 423 LEU LEU A . n 
A 1 423 PRO 423 424 424 PRO PRO A . n 
A 1 424 ASN 424 425 425 ASN ASN A . n 
A 1 425 TYR 425 426 426 TYR TYR A . n 
A 1 426 GLU 426 427 427 GLU GLU A . n 
A 1 427 SER 427 428 428 SER SER A . n 
A 1 428 ASP 428 429 429 ASP ASP A . n 
A 1 429 PRO 429 430 430 PRO PRO A . n 
A 1 430 GLY 430 431 431 GLY GLY A . n 
A 1 431 GLU 431 432 432 GLU GLU A . n 
A 1 432 HIS 432 433 433 HIS HIS A . n 
A 1 433 SER 433 434 434 SER SER A . n 
A 1 434 PHE 434 435 435 PHE PHE A . n 
A 1 435 TRP 435 436 436 TRP TRP A . n 
A 1 436 LYS 436 437 437 LYS LYS A . n 
A 1 437 LEU 437 438 438 LEU LEU A . n 
A 1 438 ILE 438 439 439 ILE ILE A . n 
A 1 439 ALA 439 440 440 ALA ALA A . n 
A 1 440 LEU 440 441 441 LEU LEU A . n 
A 1 441 PRO 441 442 442 PRO PRO A . n 
A 1 442 LYS 442 443 443 LYS LYS A . n 
A 1 443 VAL 443 444 444 VAL VAL A . n 
A 1 444 GLY 444 445 445 GLY GLY A . n 
A 1 445 LEU 445 446 446 LEU LEU A . n 
A 1 446 ILE 446 447 447 ILE ILE A . n 
A 1 447 ALA 447 448 448 ALA ALA A . n 
A 1 448 PHE 448 449 449 PHE PHE A . n 
A 1 449 VAL 449 450 450 VAL VAL A . n 
A 1 450 ILE 450 451 451 ILE ILE A . n 
A 1 451 ASN 451 452 452 ASN ASN A . n 
A 1 452 SER 452 453 453 SER SER A . n 
A 1 453 LEU 453 454 454 LEU LEU A . n 
A 1 454 SER 454 455 455 SER SER A . n 
A 1 455 SER 455 456 456 SER SER A . n 
A 1 456 CYS 456 457 457 CYS CYS A . n 
A 1 457 PHE 457 458 458 PHE PHE A . n 
A 1 458 GLY 458 459 459 GLY GLY A . n 
A 1 459 PHE 459 460 460 PHE PHE A . n 
A 1 460 LEU 460 461 461 LEU LEU A . n 
A 1 461 ASP 461 462 462 ASP ASP A . n 
A 1 462 PRO 462 463 463 PRO PRO A . n 
A 1 463 THR 463 464 464 THR THR A . n 
A 1 464 LEU 464 465 465 LEU LEU A . n 
A 1 465 SER 465 466 466 SER SER A . n 
A 1 466 LEU 466 467 467 LEU LEU A . n 
A 1 467 PHE 467 468 468 PHE PHE A . n 
A 1 468 VAL 468 469 469 VAL VAL A . n 
A 1 469 LEU 469 470 470 LEU LEU A . n 
A 1 470 GLU 470 471 471 GLU GLU A . n 
A 1 471 LYS 471 472 472 LYS LYS A . n 
A 1 472 PHE 472 473 473 PHE PHE A . n 
A 1 473 ASN 473 474 474 ASN ASN A . n 
A 1 474 LEU 474 475 475 LEU LEU A . n 
A 1 475 PRO 475 476 476 PRO PRO A . n 
A 1 476 ALA 476 477 477 ALA ALA A . n 
A 1 477 GLY 477 478 478 GLY GLY A . n 
A 1 478 TYR 478 479 479 TYR TYR A . n 
A 1 479 VAL 479 480 480 VAL VAL A . n 
A 1 480 GLY 480 481 481 GLY GLY A . n 
A 1 481 LEU 481 482 482 LEU LEU A . n 
A 1 482 VAL 482 483 483 VAL VAL A . n 
A 1 483 PHE 483 484 484 PHE PHE A . n 
A 1 484 LEU 484 485 485 LEU LEU A . n 
A 1 485 GLY 485 486 486 GLY GLY A . n 
A 1 486 MET 486 487 487 MET MET A . n 
A 1 487 ALA 487 488 488 ALA ALA A . n 
A 1 488 LEU 488 489 489 LEU LEU A . n 
A 1 489 SER 489 490 490 SER SER A . n 
A 1 490 TYR 490 491 491 TYR TYR A . n 
A 1 491 ALA 491 492 492 ALA ALA A . n 
A 1 492 ILE 492 493 493 ILE ILE A . n 
A 1 493 SER 493 494 494 SER SER A . n 
A 1 494 SER 494 495 495 SER SER A . n 
A 1 495 PRO 495 496 496 PRO PRO A . n 
A 1 496 LEU 496 497 497 LEU LEU A . n 
A 1 497 PHE 497 498 498 PHE PHE A . n 
A 1 498 GLY 498 499 499 GLY GLY A . n 
A 1 499 LEU 499 500 500 LEU LEU A . n 
A 1 500 LEU 500 501 501 LEU LEU A . n 
A 1 501 SER 501 502 502 SER SER A . n 
A 1 502 ASP 502 503 503 ASP ASP A . n 
A 1 503 LYS 503 504 504 LYS LYS A . n 
A 1 504 ARG 504 505 505 ARG ARG A . n 
A 1 505 PRO 505 506 506 PRO PRO A . n 
A 1 506 PRO 506 507 507 PRO PRO A . n 
A 1 507 LEU 507 508 508 LEU LEU A . n 
A 1 508 ARG 508 509 509 ARG ARG A . n 
A 1 509 LYS 509 510 510 LYS LYS A . n 
A 1 510 TRP 510 511 511 TRP TRP A . n 
A 1 511 LEU 511 512 512 LEU LEU A . n 
A 1 512 LEU 512 513 513 LEU LEU A . n 
A 1 513 VAL 513 514 514 VAL VAL A . n 
A 1 514 PHE 514 515 515 PHE PHE A . n 
A 1 515 GLY 515 516 516 GLY GLY A . n 
A 1 516 ASN 516 517 517 ASN ASN A . n 
A 1 517 LEU 517 518 518 LEU LEU A . n 
A 1 518 ILE 518 519 519 ILE ILE A . n 
A 1 519 THR 519 520 520 THR THR A . n 
A 1 520 ALA 520 521 521 ALA ALA A . n 
A 1 521 GLY 521 522 522 GLY GLY A . n 
A 1 522 CYS 522 523 523 CYS CYS A . n 
A 1 523 TYR 523 524 524 TYR TYR A . n 
A 1 524 MET 524 525 525 MET MET A . n 
A 1 525 LEU 525 526 526 LEU LEU A . n 
A 1 526 LEU 526 527 527 LEU LEU A . n 
A 1 527 GLY 527 528 528 GLY GLY A . n 
A 1 528 PRO 528 529 529 PRO PRO A . n 
A 1 529 VAL 529 530 530 VAL VAL A . n 
A 1 530 PRO 530 531 531 PRO PRO A . n 
A 1 531 ILE 531 532 532 ILE ILE A . n 
A 1 532 LEU 532 533 533 LEU LEU A . n 
A 1 533 HIS 533 534 534 HIS HIS A . n 
A 1 534 ILE 534 535 535 ILE ILE A . n 
A 1 535 LYS 535 536 536 LYS LYS A . n 
A 1 536 SER 536 537 537 SER SER A . n 
A 1 537 GLN 537 538 538 GLN GLN A . n 
A 1 538 LEU 538 539 539 LEU LEU A . n 
A 1 539 TRP 539 540 540 TRP TRP A . n 
A 1 540 LEU 540 541 541 LEU LEU A . n 
A 1 541 LEU 541 542 542 LEU LEU A . n 
A 1 542 VAL 542 543 543 VAL VAL A . n 
A 1 543 LEU 543 544 544 LEU LEU A . n 
A 1 544 ILE 544 545 545 ILE ILE A . n 
A 1 545 LEU 545 546 546 LEU LEU A . n 
A 1 546 VAL 546 547 547 VAL VAL A . n 
A 1 547 VAL 547 548 548 VAL VAL A . n 
A 1 548 SER 548 549 549 SER SER A . n 
A 1 549 GLY 549 550 550 GLY GLY A . n 
A 1 550 LEU 550 551 551 LEU LEU A . n 
A 1 551 SER 551 552 552 SER SER A . n 
A 1 552 ALA 552 553 553 ALA ALA A . n 
A 1 553 GLY 553 554 554 GLY GLY A . n 
A 1 554 MET 554 555 555 MET MET A . n 
A 1 555 SER 555 556 556 SER SER A . n 
A 1 556 ILE 556 557 557 ILE ILE A . n 
A 1 557 ILE 557 558 558 ILE ILE A . n 
A 1 558 PRO 558 559 559 PRO PRO A . n 
A 1 559 THR 559 560 560 THR THR A . n 
A 1 560 PHE 560 561 561 PHE PHE A . n 
A 1 561 PRO 561 562 562 PRO PRO A . n 
A 1 562 GLU 562 563 563 GLU GLU A . n 
A 1 563 ILE 563 564 564 ILE ILE A . n 
A 1 564 LEU 564 565 565 LEU LEU A . n 
A 1 565 SER 565 566 566 SER SER A . n 
A 1 566 CYS 566 567 567 CYS CYS A . n 
A 1 567 ALA 567 568 568 ALA ALA A . n 
A 1 568 HIS 568 569 569 HIS HIS A . n 
A 1 569 GLU 569 570 570 GLU GLU A . n 
A 1 570 ASN 570 571 571 ASN ASN A . n 
A 1 571 GLY 571 572 572 GLY GLY A . n 
A 1 572 PHE 572 573 573 PHE PHE A . n 
A 1 573 GLU 573 574 574 GLU GLU A . n 
A 1 574 GLU 574 575 575 GLU GLU A . n 
A 1 575 GLY 575 576 576 GLY GLY A . n 
A 1 576 LEU 576 577 577 LEU LEU A . n 
A 1 577 SER 577 578 578 SER SER A . n 
A 1 578 THR 578 579 579 THR THR A . n 
A 1 579 LEU 579 580 580 LEU LEU A . n 
A 1 580 GLY 580 581 581 GLY GLY A . n 
A 1 581 LEU 581 582 582 LEU LEU A . n 
A 1 582 VAL 582 583 583 VAL VAL A . n 
A 1 583 SER 583 584 584 SER SER A . n 
A 1 584 GLY 584 585 585 GLY GLY A . n 
A 1 585 LEU 585 586 586 LEU LEU A . n 
A 1 586 PHE 586 587 587 PHE PHE A . n 
A 1 587 SER 587 588 588 SER SER A . n 
A 1 588 ALA 588 589 589 ALA ALA A . n 
A 1 589 MET 589 590 590 MET MET A . n 
A 1 590 TRP 590 591 591 TRP TRP A . n 
A 1 591 SER 591 592 592 SER SER A . n 
A 1 592 ILE 592 593 593 ILE ILE A . n 
A 1 593 GLY 593 594 594 GLY GLY A . n 
A 1 594 ALA 594 595 595 ALA ALA A . n 
A 1 595 PHE 595 596 596 PHE PHE A . n 
A 1 596 MET 596 597 597 MET MET A . n 
A 1 597 GLY 597 598 598 GLY GLY A . n 
A 1 598 PRO 598 599 599 PRO PRO A . n 
A 1 599 THR 599 600 600 THR THR A . n 
A 1 600 LEU 600 601 601 LEU LEU A . n 
A 1 601 GLY 601 602 602 GLY GLY A . n 
A 1 602 GLY 602 603 603 GLY GLY A . n 
A 1 603 PHE 603 604 604 PHE PHE A . n 
A 1 604 LEU 604 605 605 LEU LEU A . n 
A 1 605 TYR 605 606 606 TYR TYR A . n 
A 1 606 GLU 606 607 607 GLU GLU A . n 
A 1 607 LYS 607 608 608 LYS LYS A . n 
A 1 608 ILE 608 609 609 ILE ILE A . n 
A 1 609 GLY 609 610 610 GLY GLY A . n 
A 1 610 PHE 610 611 611 PHE PHE A . n 
A 1 611 GLU 611 612 612 GLU GLU A . n 
A 1 612 TRP 612 613 613 TRP TRP A . n 
A 1 613 ALA 613 614 614 ALA ALA A . n 
A 1 614 ALA 614 615 615 ALA ALA A . n 
A 1 615 ALA 615 616 616 ALA ALA A . n 
A 1 616 ILE 616 617 617 ILE ILE A . n 
A 1 617 GLN 617 618 618 GLN GLN A . n 
A 1 618 GLY 618 619 619 GLY GLY A . n 
A 1 619 LEU 619 620 620 LEU LEU A . n 
A 1 620 TRP 620 621 621 TRP TRP A . n 
A 1 621 ALA 621 622 622 ALA ALA A . n 
A 1 622 LEU 622 623 623 LEU LEU A . n 
A 1 623 ILE 623 624 624 ILE ILE A . n 
A 1 624 SER 624 625 625 SER SER A . n 
A 1 625 GLY 625 626 626 GLY GLY A . n 
A 1 626 LEU 626 627 627 LEU LEU A . n 
A 1 627 ALA 627 628 628 ALA ALA A . n 
A 1 628 MET 628 629 629 MET MET A . n 
A 1 629 GLY 629 630 630 GLY GLY A . n 
A 1 630 LEU 630 631 631 LEU LEU A . n 
A 1 631 PHE 631 632 632 PHE PHE A . n 
A 1 632 TYR 632 633 633 TYR TYR A . n 
A 1 633 LEU 633 634 634 LEU LEU A . n 
A 1 634 LEU 634 635 635 LEU LEU A . n 
A 1 635 GLU 635 636 636 GLU GLU A . n 
A 1 636 TYR 636 637 637 TYR TYR A . n 
A 1 637 SER 637 638 638 SER SER A . n 
A 1 638 GLN 638 639 639 GLN GLN A . n 
A 1 639 VAL 639 640 640 VAL VAL A . n 
A 1 640 GLN 640 641 641 GLN GLN A . n 
A 1 641 LEU 641 642 642 LEU LEU A . n 
A 1 642 VAL 642 643 643 VAL VAL A . n 
A 1 643 GLU 643 644 644 GLU GLU A . n 
A 1 644 SER 644 645 645 SER SER A . n 
A 1 645 GLY 645 646 646 GLY GLY A . n 
A 1 646 GLY 646 647 647 GLY GLY A . n 
A 1 647 ALA 647 648 648 ALA ALA A . n 
A 1 648 LEU 648 649 649 LEU LEU A . n 
A 1 649 VAL 649 650 650 VAL VAL A . n 
A 1 650 GLN 650 651 651 GLN GLN A . n 
A 1 651 PRO 651 652 652 PRO PRO A . n 
A 1 652 GLY 652 653 653 GLY GLY A . n 
A 1 653 GLY 653 654 654 GLY GLY A . n 
A 1 654 SER 654 655 655 SER SER A . n 
A 1 655 LEU 655 656 656 LEU LEU A . n 
A 1 656 ARG 656 657 657 ARG ARG A . n 
A 1 657 LEU 657 658 658 LEU LEU A . n 
A 1 658 SER 658 659 659 SER SER A . n 
A 1 659 CYS 659 660 660 CYS CYS A . n 
A 1 660 ALA 660 661 661 ALA ALA A . n 
A 1 661 ALA 661 662 662 ALA ALA A . n 
A 1 662 SER 662 663 663 SER SER A . n 
A 1 663 GLY 663 664 664 GLY GLY A . n 
A 1 664 PHE 664 665 665 PHE PHE A . n 
A 1 665 PRO 665 666 666 PRO PRO A . n 
A 1 666 VAL 666 667 667 VAL VAL A . n 
A 1 667 ASN 667 668 668 ASN ASN A . n 
A 1 668 ARG 668 669 669 ARG ARG A . n 
A 1 669 TYR 669 670 670 TYR TYR A . n 
A 1 670 SER 670 671 671 SER SER A . n 
A 1 671 MET 671 672 672 MET MET A . n 
A 1 672 ARG 672 673 673 ARG ARG A . n 
A 1 673 TRP 673 674 674 TRP TRP A . n 
A 1 674 TYR 674 675 675 TYR TYR A . n 
A 1 675 ARG 675 676 676 ARG ARG A . n 
A 1 676 GLN 676 677 677 GLN GLN A . n 
A 1 677 ALA 677 678 678 ALA ALA A . n 
A 1 678 PRO 678 679 679 PRO PRO A . n 
A 1 679 GLY 679 680 680 GLY GLY A . n 
A 1 680 LYS 680 681 681 LYS LYS A . n 
A 1 681 GLU 681 682 682 GLU GLU A . n 
A 1 682 ARG 682 683 683 ARG ARG A . n 
A 1 683 GLU 683 684 684 GLU GLU A . n 
A 1 684 TRP 684 685 685 TRP TRP A . n 
A 1 685 VAL 685 686 686 VAL VAL A . n 
A 1 686 ALA 686 687 687 ALA ALA A . n 
A 1 687 GLY 687 688 688 GLY GLY A . n 
A 1 688 MET 688 689 689 MET MET A . n 
A 1 689 SER 689 690 690 SER SER A . n 
A 1 690 SER 690 691 691 SER SER A . n 
A 1 691 ALA 691 692 692 ALA ALA A . n 
A 1 692 GLY 692 693 693 GLY GLY A . n 
A 1 693 ASP 693 694 694 ASP ASP A . n 
A 1 694 ARG 694 695 695 ARG ARG A . n 
A 1 695 SER 695 696 696 SER SER A . n 
A 1 696 SER 696 697 697 SER SER A . n 
A 1 697 TYR 697 698 698 TYR TYR A . n 
A 1 698 GLU 698 699 699 GLU GLU A . n 
A 1 699 ASP 699 700 700 ASP ASP A . n 
A 1 700 SER 700 701 701 SER SER A . n 
A 1 701 VAL 701 702 702 VAL VAL A . n 
A 1 702 LYS 702 703 703 LYS LYS A . n 
A 1 703 GLY 703 704 704 GLY GLY A . n 
A 1 704 ARG 704 705 705 ARG ARG A . n 
A 1 705 PHE 705 706 706 PHE PHE A . n 
A 1 706 THR 706 707 707 THR THR A . n 
A 1 707 ILE 707 708 708 ILE ILE A . n 
A 1 708 SER 708 709 709 SER SER A . n 
A 1 709 ARG 709 710 710 ARG ARG A . n 
A 1 710 ASP 710 711 711 ASP ASP A . n 
A 1 711 ASP 711 712 712 ASP ASP A . n 
A 1 712 ALA 712 713 713 ALA ALA A . n 
A 1 713 ARG 713 714 714 ARG ARG A . n 
A 1 714 ASN 714 715 715 ASN ASN A . n 
A 1 715 THR 715 716 716 THR THR A . n 
A 1 716 VAL 716 717 717 VAL VAL A . n 
A 1 717 TYR 717 718 718 TYR TYR A . n 
A 1 718 LEU 718 719 719 LEU LEU A . n 
A 1 719 GLN 719 720 720 GLN GLN A . n 
A 1 720 MET 720 721 721 MET MET A . n 
A 1 721 ASN 721 722 722 ASN ASN A . n 
A 1 722 SER 722 723 723 SER SER A . n 
A 1 723 LEU 723 724 724 LEU LEU A . n 
A 1 724 LYS 724 725 725 LYS LYS A . n 
A 1 725 PRO 725 726 726 PRO PRO A . n 
A 1 726 GLU 726 727 727 GLU GLU A . n 
A 1 727 ASP 727 728 728 ASP ASP A . n 
A 1 728 THR 728 729 729 THR THR A . n 
A 1 729 ALA 729 730 730 ALA ALA A . n 
A 1 730 VAL 730 731 731 VAL VAL A . n 
A 1 731 TYR 731 732 732 TYR TYR A . n 
A 1 732 TYR 732 733 733 TYR TYR A . n 
A 1 733 CYS 733 734 734 CYS CYS A . n 
A 1 734 ASN 734 735 735 ASN ASN A . n 
A 1 735 VAL 735 736 736 VAL VAL A . n 
A 1 736 ASN 736 737 737 ASN ASN A . n 
A 1 737 VAL 737 738 738 VAL VAL A . n 
A 1 738 GLY 738 739 739 GLY GLY A . n 
A 1 739 PHE 739 740 740 PHE PHE A . n 
A 1 740 GLU 740 741 741 GLU GLU A . n 
A 1 741 TYR 741 742 742 TYR TYR A . n 
A 1 742 TRP 742 743 743 TRP TRP A . n 
A 1 743 GLY 743 744 744 GLY GLY A . n 
A 1 744 GLN 744 745 745 GLN GLN A . n 
A 1 745 GLY 745 746 746 GLY GLY A . n 
A 1 746 THR 746 747 747 THR THR A . n 
A 1 747 GLN 747 748 748 GLN GLN A . n 
A 1 748 VAL 748 749 749 VAL VAL A . n 
A 1 749 THR 749 750 750 THR THR A . n 
A 1 750 VAL 750 751 751 VAL VAL A . n 
A 1 751 SER 751 752 752 SER SER A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 SPD 1 801 1 SPD SPD A . 
C 3 HOH 1 901 1 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A ARG 344 ? N ? A ARG 343 N 
2 1 Y 1 A TRP 436 ? N ? A TRP 435 N 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9D7V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9D7V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9D7V 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9D7V 
_struct.title                        'The spd-bound structure' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9D7V 
_struct_keywords.text            'membrane protein' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A0A125NTU3_HYPSL A0A125NTU3 ? 1 
;LSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFGYGLQCFARYPDHMKQ
HDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNG
IKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSYQSALSKDPNEKRDHMVLLEFVTAAGIT
;
2   
2 UNP S18B1_HUMAN      Q6NT16     ? 1 
;TPGWLSREQVFVLISAASVNLGSMMCYSILGPFFPKEAEKKGASNTIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFV
AGMFVSGGVTILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAFPNNVATVLGSLETFSGLGLILGPPV
GGFLYQSFGYEVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPKVGLIAFVINSLSSCFGFLDPTLSLFVLE
KFNLPAGYVGLVFLGMALSYAISSPLFGLLSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGL
SAGMSIIPTFPEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGLWALISGLAMGL
FYLLEYS
;
25  
3 PDB 9D7V             9D7V       ? 1 ? 638 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9D7V A 1   ? 230 ? A0A125NTU3 2   ? 231 ? 2   231 
2 2 9D7V A 231 ? 637 ? Q6NT16     25  ? 431 ? 232 638 
3 3 9D7V A 638 ? 751 ? 9D7V       639 ? 752 ? 639 752 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9D7V VAL A 1   ? UNP A0A125NTU3 LEU 2   conflict 2   1 
1 9D7V LEU A 46  ? UNP A0A125NTU3 PHE 47  conflict 47  2 
1 9D7V LEU A 64  ? UNP A0A125NTU3 PHE 65  conflict 65  3 
1 9D7V THR A 153 ? UNP A0A125NTU3 MET 154 conflict 154 4 
1 9D7V ALA A 163 ? UNP A0A125NTU3 VAL 164 conflict 164 5 
1 9D7V GLY A 175 ? UNP A0A125NTU3 SER 176 conflict 176 6 
1 9D7V LYS A 206 ? UNP A0A125NTU3 ALA 207 conflict 207 7 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 2   ? THR A 9   ? SER A 3   THR A 10  5 ? 8  
HELX_P HELX_P2  AA2 TRP A 57  ? GLY A 65  ? TRP A 58  GLY A 66  1 ? 9  
HELX_P HELX_P3  AA3 LEU A 68  ? ALA A 72  ? LEU A 69  ALA A 73  5 ? 5  
HELX_P HELX_P4  AA4 ASP A 76  ? GLN A 80  ? ASP A 77  GLN A 81  5 ? 5  
HELX_P HELX_P5  AA5 SER A 236 ? SER A 258 ? SER A 237 SER A 259 1 ? 23 
HELX_P HELX_P6  AA6 MET A 280 ? TYR A 299 ? MET A 281 TYR A 300 1 ? 20 
HELX_P HELX_P7  AA7 TYR A 299 ? GLY A 304 ? TYR A 300 GLY A 305 1 ? 6  
HELX_P HELX_P8  AA8 GLY A 304 ? PHE A 323 ? GLY A 305 PHE A 324 1 ? 20 
HELX_P HELX_P9  AA9 GLY A 324 ? ASP A 327 ? GLY A 325 ASP A 328 5 ? 4  
HELX_P HELX_P10 AB1 PHE A 335 ? VAL A 342 ? PHE A 336 VAL A 343 1 ? 8  
HELX_P HELX_P11 AB2 VAL A 344 ? PHE A 365 ? VAL A 345 PHE A 366 1 ? 22 
HELX_P HELX_P12 AB3 ASN A 368 ? GLY A 381 ? ASN A 369 GLY A 382 1 ? 14 
HELX_P HELX_P13 AB4 PHE A 393 ? PHE A 398 ? PHE A 394 PHE A 399 1 ? 6  
HELX_P HELX_P14 AB5 PRO A 403 ? LEU A 413 ? PRO A 404 LEU A 414 1 ? 11 
HELX_P HELX_P15 AB6 LEU A 413 ? LEU A 422 ? LEU A 414 LEU A 423 1 ? 10 
HELX_P HELX_P16 AB7 SER A 433 ? PHE A 434 ? SER A 434 PHE A 435 1 ? 2  
HELX_P HELX_P17 AB8 LYS A 436 ? ILE A 438 ? LYS A 437 ILE A 439 1 ? 3  
HELX_P HELX_P18 AB9 LEU A 440 ? PHE A 472 ? LEU A 441 PHE A 473 1 ? 33 
HELX_P HELX_P19 AC1 PRO A 475 ? ARG A 504 ? PRO A 476 ARG A 505 1 ? 30 
HELX_P HELX_P20 AC2 LEU A 507 ? LEU A 525 ? LEU A 508 LEU A 526 1 ? 19 
HELX_P HELX_P21 AC3 GLN A 537 ? ILE A 557 ? GLN A 538 ILE A 558 1 ? 21 
HELX_P HELX_P22 AC4 PRO A 558 ? GLY A 571 ? PRO A 559 GLY A 572 1 ? 14 
HELX_P HELX_P23 AC5 GLY A 575 ? GLY A 597 ? GLY A 576 GLY A 598 1 ? 23 
HELX_P HELX_P24 AC6 GLY A 597 ? ILE A 608 ? GLY A 598 ILE A 609 1 ? 12 
HELX_P HELX_P25 AC7 GLY A 609 ? ALA A 614 ? GLY A 610 ALA A 615 1 ? 6  
HELX_P HELX_P26 AC8 ALA A 614 ? GLU A 635 ? ALA A 615 GLU A 636 1 ? 22 
HELX_P HELX_P27 AC9 LYS A 724 ? THR A 728 ? LYS A 725 THR A 729 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            659 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           A 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            733 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             660 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             734 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.037 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       659 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      733 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        660 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       734 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 12 ? 
AA2 ? 4  ? 
AA3 ? 6  ? 
AA4 ? 4  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA1 7  8  ? anti-parallel 
AA1 8  9  ? anti-parallel 
AA1 9  10 ? anti-parallel 
AA1 10 11 ? anti-parallel 
AA1 11 12 ? parallel      
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA3 1  2  ? parallel      
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
AA3 5  6  ? anti-parallel 
AA4 1  2  ? parallel      
AA4 2  3  ? anti-parallel 
AA4 3  4  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  VAL A 11  ? VAL A 22  ? VAL A 12  VAL A 23  
AA1 2  HIS A 25  ? ASP A 36  ? HIS A 26  ASP A 37  
AA1 3  LYS A 41  ? CYS A 48  ? LYS A 42  CYS A 49  
AA1 4  HIS A 217 ? ALA A 227 ? HIS A 218 ALA A 228 
AA1 5  HIS A 199 ? SER A 208 ? HIS A 200 SER A 209 
AA1 6  HIS A 148 ? ALA A 154 ? HIS A 149 ALA A 155 
AA1 7  ILE A 161 ? ASN A 170 ? ILE A 162 ASN A 171 
AA1 8  VAL A 176 ? PRO A 187 ? VAL A 177 PRO A 188 
AA1 9  TYR A 92  ? PHE A 100 ? TYR A 93  PHE A 101 
AA1 10 ASN A 105 ? GLU A 115 ? ASN A 106 GLU A 116 
AA1 11 THR A 118 ? ILE A 128 ? THR A 119 ILE A 129 
AA1 12 VAL A 11  ? VAL A 22  ? VAL A 12  VAL A 23  
AA2 1  GLN A 640 ? SER A 644 ? GLN A 641 SER A 645 
AA2 2  SER A 654 ? SER A 662 ? SER A 655 SER A 663 
AA2 3  THR A 715 ? ASN A 721 ? THR A 716 ASN A 722 
AA2 4  PHE A 705 ? ASP A 710 ? PHE A 706 ASP A 711 
AA3 1  LEU A 648 ? VAL A 649 ? LEU A 649 VAL A 650 
AA3 2  THR A 746 ? VAL A 750 ? THR A 747 VAL A 751 
AA3 3  ALA A 729 ? ASN A 736 ? ALA A 730 ASN A 737 
AA3 4  ARG A 672 ? GLN A 676 ? ARG A 673 GLN A 677 
AA3 5  GLU A 683 ? MET A 688 ? GLU A 684 MET A 689 
AA3 6  SER A 695 ? TYR A 697 ? SER A 696 TYR A 698 
AA4 1  LEU A 648 ? VAL A 649 ? LEU A 649 VAL A 650 
AA4 2  THR A 746 ? VAL A 750 ? THR A 747 VAL A 751 
AA4 3  ALA A 729 ? ASN A 736 ? ALA A 730 ASN A 737 
AA4 4  GLU A 740 ? TRP A 742 ? GLU A 741 TRP A 743 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N VAL A 12  ? N VAL A 13  O GLY A 35  ? O GLY A 36  
AA1 2  3  N GLU A 34  ? N GLU A 35  O THR A 43  ? O THR A 44  
AA1 3  4  N LEU A 44  ? N LEU A 45  O LEU A 220 ? O LEU A 221 
AA1 4  5  O ALA A 227 ? O ALA A 228 N TYR A 200 ? N TYR A 201 
AA1 5  6  O TYR A 203 ? O TYR A 204 N HIS A 148 ? N HIS A 149 
AA1 6  7  N THR A 153 ? N THR A 154 O LYS A 162 ? O LYS A 163 
AA1 7  8  N PHE A 165 ? N PHE A 166 O HIS A 181 ? O HIS A 182 
AA1 8  9  O ASP A 180 ? O ASP A 181 N PHE A 99  ? N PHE A 100 
AA1 9  10 N GLN A 94  ? N GLN A 95  O ALA A 110 ? O ALA A 111 
AA1 10 11 N LYS A 113 ? N LYS A 114 O VAL A 120 ? O VAL A 121 
AA1 11 12 O ILE A 123 ? O ILE A 124 N ASP A 19  ? N ASP A 20  
AA2 1  2  N VAL A 642 ? N VAL A 643 O ALA A 660 ? O ALA A 661 
AA2 2  3  N CYS A 659 ? N CYS A 660 O VAL A 716 ? O VAL A 717 
AA2 3  4  O GLN A 719 ? O GLN A 720 N THR A 706 ? N THR A 707 
AA3 1  2  N VAL A 649 ? N VAL A 650 O THR A 749 ? O THR A 750 
AA3 2  3  O THR A 746 ? O THR A 747 N TYR A 731 ? N TYR A 732 
AA3 3  4  O ASN A 734 ? O ASN A 735 N ARG A 672 ? N ARG A 673 
AA3 4  5  N ARG A 675 ? N ARG A 676 O GLU A 683 ? O GLU A 684 
AA3 5  6  N GLY A 687 ? N GLY A 688 O SER A 696 ? O SER A 697 
AA4 1  2  N VAL A 649 ? N VAL A 650 O THR A 749 ? O THR A 750 
AA4 2  3  O THR A 746 ? O THR A 747 N TYR A 731 ? N TYR A 732 
AA4 3  4  N VAL A 735 ? N VAL A 736 O TYR A 741 ? O TYR A 742 
# 
_pdbx_entry_details.entry_id                   9D7V 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 C A ARG 344 ? ? N A VAL 345 ? ? 1.600 1.336 0.264  0.023 Y 
2 1 C A TRP 436 ? ? N A LYS 437 ? ? 1.161 1.336 -0.175 0.023 Y 
3 1 C A LEU 620 ? ? N A TRP 621 ? ? 1.149 1.336 -0.187 0.023 Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_1              734 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_2              734 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             SG 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_3              734 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                121.76 
_pdbx_validate_rmsd_angle.angle_target_value         114.20 
_pdbx_validate_rmsd_angle.angle_deviation            7.56 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 65  ? ? -92.36  -62.16 
2 1 PHE A 72  ? ? -95.14  30.62  
3 1 ASP A 103 ? ? 35.22   41.40  
4 1 ASN A 369 ? ? -143.06 26.50  
5 1 ILE A 609 ? ? -121.63 -61.00 
6 1 VAL A 686 ? ? -107.35 -62.30 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     344 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.267 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_validate_polymer_linkage.id 
_pdbx_validate_polymer_linkage.PDB_model_num 
_pdbx_validate_polymer_linkage.auth_atom_id_1 
_pdbx_validate_polymer_linkage.auth_asym_id_1 
_pdbx_validate_polymer_linkage.auth_comp_id_1 
_pdbx_validate_polymer_linkage.auth_seq_id_1 
_pdbx_validate_polymer_linkage.PDB_ins_code_1 
_pdbx_validate_polymer_linkage.label_alt_id_1 
_pdbx_validate_polymer_linkage.auth_atom_id_2 
_pdbx_validate_polymer_linkage.auth_asym_id_2 
_pdbx_validate_polymer_linkage.auth_comp_id_2 
_pdbx_validate_polymer_linkage.auth_seq_id_2 
_pdbx_validate_polymer_linkage.PDB_ins_code_2 
_pdbx_validate_polymer_linkage.label_alt_id_2 
_pdbx_validate_polymer_linkage.dist 
1 1 C A ARG 344 ? ? N A VAL 345 ? ? 1.60 
2 1 C A TRP 436 ? ? N A LYS 437 ? ? 1.16 
3 1 C A LEU 620 ? ? N A TRP 621 ? ? 1.15 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9D7V 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9D7V 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               98600 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            4.9 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 'fusion protein' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9D7V 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9D7V 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9D7V 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A PRO 263 ? A PRO 262 
2  1 Y 1 A PHE 264 ? A PHE 263 
3  1 Y 1 A PHE 265 ? A PHE 264 
4  1 Y 1 A PRO 266 ? A PRO 265 
5  1 Y 1 A LYS 267 ? A LYS 266 
6  1 Y 1 A GLU 268 ? A GLU 267 
7  1 Y 1 A ALA 269 ? A ALA 268 
8  1 Y 1 A GLU 270 ? A GLU 269 
9  1 Y 1 A LYS 271 ? A LYS 270 
10 1 Y 1 A LYS 272 ? A LYS 271 
11 1 Y 1 A GLY 273 ? A GLY 272 
12 1 Y 1 A ALA 274 ? A ALA 273 
13 1 Y 1 A SER 275 ? A SER 274 
14 1 Y 1 A ASN 276 ? A ASN 275 
15 1 Y 1 A THR 277 ? A THR 276 
16 1 Y 1 A ILE 278 ? A ILE 277 
17 1 Y 1 A ILE 279 ? A ILE 278 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
SPD N1   N N N 304 
SPD C2   C N N 305 
SPD C3   C N N 306 
SPD C4   C N N 307 
SPD C5   C N N 308 
SPD N6   N N N 309 
SPD C7   C N N 310 
SPD C8   C N N 311 
SPD C9   C N N 312 
SPD N10  N N N 313 
SPD HN11 H N N 314 
SPD HN12 H N N 315 
SPD H21  H N N 316 
SPD H22  H N N 317 
SPD H31  H N N 318 
SPD H32  H N N 319 
SPD H41  H N N 320 
SPD H42  H N N 321 
SPD H51  H N N 322 
SPD H52  H N N 323 
SPD HN6  H N N 324 
SPD H71  H N N 325 
SPD H72  H N N 326 
SPD H81  H N N 327 
SPD H82  H N N 328 
SPD H91  H N N 329 
SPD H92  H N N 330 
SPD H101 H N N 331 
SPD H102 H N N 332 
THR N    N N N 333 
THR CA   C N S 334 
THR C    C N N 335 
THR O    O N N 336 
THR CB   C N R 337 
THR OG1  O N N 338 
THR CG2  C N N 339 
THR OXT  O N N 340 
THR H    H N N 341 
THR H2   H N N 342 
THR HA   H N N 343 
THR HB   H N N 344 
THR HG1  H N N 345 
THR HG21 H N N 346 
THR HG22 H N N 347 
THR HG23 H N N 348 
THR HXT  H N N 349 
TRP N    N N N 350 
TRP CA   C N S 351 
TRP C    C N N 352 
TRP O    O N N 353 
TRP CB   C N N 354 
TRP CG   C Y N 355 
TRP CD1  C Y N 356 
TRP CD2  C Y N 357 
TRP NE1  N Y N 358 
TRP CE2  C Y N 359 
TRP CE3  C Y N 360 
TRP CZ2  C Y N 361 
TRP CZ3  C Y N 362 
TRP CH2  C Y N 363 
TRP OXT  O N N 364 
TRP H    H N N 365 
TRP H2   H N N 366 
TRP HA   H N N 367 
TRP HB2  H N N 368 
TRP HB3  H N N 369 
TRP HD1  H N N 370 
TRP HE1  H N N 371 
TRP HE3  H N N 372 
TRP HZ2  H N N 373 
TRP HZ3  H N N 374 
TRP HH2  H N N 375 
TRP HXT  H N N 376 
TYR N    N N N 377 
TYR CA   C N S 378 
TYR C    C N N 379 
TYR O    O N N 380 
TYR CB   C N N 381 
TYR CG   C Y N 382 
TYR CD1  C Y N 383 
TYR CD2  C Y N 384 
TYR CE1  C Y N 385 
TYR CE2  C Y N 386 
TYR CZ   C Y N 387 
TYR OH   O N N 388 
TYR OXT  O N N 389 
TYR H    H N N 390 
TYR H2   H N N 391 
TYR HA   H N N 392 
TYR HB2  H N N 393 
TYR HB3  H N N 394 
TYR HD1  H N N 395 
TYR HD2  H N N 396 
TYR HE1  H N N 397 
TYR HE2  H N N 398 
TYR HH   H N N 399 
TYR HXT  H N N 400 
VAL N    N N N 401 
VAL CA   C N S 402 
VAL C    C N N 403 
VAL O    O N N 404 
VAL CB   C N N 405 
VAL CG1  C N N 406 
VAL CG2  C N N 407 
VAL OXT  O N N 408 
VAL H    H N N 409 
VAL H2   H N N 410 
VAL HA   H N N 411 
VAL HB   H N N 412 
VAL HG11 H N N 413 
VAL HG12 H N N 414 
VAL HG13 H N N 415 
VAL HG21 H N N 416 
VAL HG22 H N N 417 
VAL HG23 H N N 418 
VAL HXT  H N N 419 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
SPD N1  C2   sing N N 290 
SPD N1  HN11 sing N N 291 
SPD N1  HN12 sing N N 292 
SPD C2  C3   sing N N 293 
SPD C2  H21  sing N N 294 
SPD C2  H22  sing N N 295 
SPD C3  C4   sing N N 296 
SPD C3  H31  sing N N 297 
SPD C3  H32  sing N N 298 
SPD C4  C5   sing N N 299 
SPD C4  H41  sing N N 300 
SPD C4  H42  sing N N 301 
SPD C5  N6   sing N N 302 
SPD C5  H51  sing N N 303 
SPD C5  H52  sing N N 304 
SPD N6  C7   sing N N 305 
SPD N6  HN6  sing N N 306 
SPD C7  C8   sing N N 307 
SPD C7  H71  sing N N 308 
SPD C7  H72  sing N N 309 
SPD C8  C9   sing N N 310 
SPD C8  H81  sing N N 311 
SPD C8  H82  sing N N 312 
SPD C9  N10  sing N N 313 
SPD C9  H91  sing N N 314 
SPD C9  H92  sing N N 315 
SPD N10 H101 sing N N 316 
SPD N10 H102 sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-17 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9D7V 
_em_admin.last_update        2025-06-25 
_em_admin.map_release_date   2025-06-25 
_em_admin.title              'The spd-bound structure' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                90 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          266783 
_em_entity_assembly_recombinant.organism             'Insect cell expression vector pTIE1' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         30 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?          
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.21_5207: 
'IMAGE ACQUISITION'        ? 3  1 1 1 ?      ?          
MASKING                    ? 4  1 1 1 ?      ?          
'CTF CORRECTION'           ? 5  1 ? ? ?      ?          
'LAYERLINE INDEXING'       ? 6  1 1 1 ?      ?          
'DIFFRACTION INDEXING'     ? 7  1 1 1 ?      ?          
'MODEL FITTING'            ? 8  1 1 1 ?      ?          
OTHER                      ? 9  1 1 1 ?      ?          
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?          
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?          
CLASSIFICATION             ? 12 1 ? ? ?      ?          
RECONSTRUCTION             ? 13 1 ? ? ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R01GM145642 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9D7V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . VAL A 1 1   ? 132.911 114.820 125.005 1.00 162.49 ? 2   VAL A N   1 
ATOM   2    C CA  . VAL A 1 1   ? 134.298 114.683 125.428 1.00 170.56 ? 2   VAL A CA  1 
ATOM   3    C C   . VAL A 1 1   ? 134.980 113.557 124.659 1.00 171.13 ? 2   VAL A C   1 
ATOM   4    O O   . VAL A 1 1   ? 134.768 112.377 124.943 1.00 170.40 ? 2   VAL A O   1 
ATOM   5    C CB  . VAL A 1 1   ? 134.396 114.444 126.944 1.00 164.68 ? 2   VAL A CB  1 
ATOM   6    C CG1 . VAL A 1 1   ? 135.851 114.454 127.389 1.00 164.24 ? 2   VAL A CG1 1 
ATOM   7    C CG2 . VAL A 1 1   ? 133.597 115.497 127.697 1.00 160.42 ? 2   VAL A CG2 1 
ATOM   8    N N   . SER A 1 2   ? 135.800 113.932 123.682 1.00 170.86 ? 3   SER A N   1 
ATOM   9    C CA  . SER A 1 2   ? 136.491 112.954 122.859 1.00 164.82 ? 3   SER A CA  1 
ATOM   10   C C   . SER A 1 2   ? 137.788 112.499 123.525 1.00 157.93 ? 3   SER A C   1 
ATOM   11   O O   . SER A 1 2   ? 138.204 113.016 124.566 1.00 159.16 ? 3   SER A O   1 
ATOM   12   C CB  . SER A 1 2   ? 136.788 113.533 121.478 1.00 154.74 ? 3   SER A CB  1 
ATOM   13   O OG  . SER A 1 2   ? 137.669 114.640 121.570 1.00 152.23 ? 3   SER A OG  1 
ATOM   14   N N   . LYS A 1 3   ? 138.427 111.505 122.903 1.00 145.49 ? 4   LYS A N   1 
ATOM   15   C CA  . LYS A 1 3   ? 139.666 110.951 123.436 1.00 147.45 ? 4   LYS A CA  1 
ATOM   16   C C   . LYS A 1 3   ? 140.846 111.903 123.287 1.00 148.25 ? 4   LYS A C   1 
ATOM   17   O O   . LYS A 1 3   ? 141.666 112.002 124.207 1.00 148.24 ? 4   LYS A O   1 
ATOM   18   C CB  . LYS A 1 3   ? 139.977 109.621 122.747 1.00 142.21 ? 4   LYS A CB  1 
ATOM   19   C CG  . LYS A 1 3   ? 141.196 108.895 123.295 1.00 134.26 ? 4   LYS A CG  1 
ATOM   20   C CD  . LYS A 1 3   ? 141.405 107.565 122.597 1.00 135.24 ? 4   LYS A CD  1 
ATOM   21   C CE  . LYS A 1 3   ? 142.560 106.800 123.216 1.00 140.43 ? 4   LYS A CE  1 
ATOM   22   N NZ  . LYS A 1 3   ? 143.864 107.474 122.971 1.00 138.46 ? 4   LYS A NZ  1 
ATOM   23   N N   . GLY A 1 4   ? 140.933 112.626 122.172 1.00 145.35 ? 5   GLY A N   1 
ATOM   24   C CA  . GLY A 1 4   ? 142.098 113.416 121.828 1.00 144.62 ? 5   GLY A CA  1 
ATOM   25   C C   . GLY A 1 4   ? 142.338 114.671 122.635 1.00 143.38 ? 5   GLY A C   1 
ATOM   26   O O   . GLY A 1 4   ? 143.350 115.342 122.417 1.00 142.52 ? 5   GLY A O   1 
ATOM   27   N N   . GLU A 1 5   ? 141.437 115.019 123.556 1.00 142.85 ? 6   GLU A N   1 
ATOM   28   C CA  . GLU A 1 5   ? 141.627 116.219 124.363 1.00 147.09 ? 6   GLU A CA  1 
ATOM   29   C C   . GLU A 1 5   ? 142.722 116.024 125.408 1.00 148.10 ? 6   GLU A C   1 
ATOM   30   O O   . GLU A 1 5   ? 143.383 116.994 125.802 1.00 150.19 ? 6   GLU A O   1 
ATOM   31   C CB  . GLU A 1 5   ? 140.299 116.605 125.023 1.00 152.91 ? 6   GLU A CB  1 
ATOM   32   C CG  . GLU A 1 5   ? 140.289 117.948 125.742 1.00 154.56 ? 6   GLU A CG  1 
ATOM   33   C CD  . GLU A 1 5   ? 139.298 117.985 126.888 1.00 156.86 ? 6   GLU A CD  1 
ATOM   34   O OE1 . GLU A 1 5   ? 138.482 117.047 127.000 1.00 156.06 ? 6   GLU A OE1 1 
ATOM   35   O OE2 . GLU A 1 5   ? 139.336 118.952 127.678 1.00 157.79 ? 6   GLU A OE2 1 
ATOM   36   N N   . GLU A 1 6   ? 142.944 114.782 125.847 1.00 145.47 ? 7   GLU A N   1 
ATOM   37   C CA  . GLU A 1 6   ? 143.927 114.517 126.894 1.00 149.48 ? 7   GLU A CA  1 
ATOM   38   C C   . GLU A 1 6   ? 145.357 114.691 126.396 1.00 145.02 ? 7   GLU A C   1 
ATOM   39   O O   . GLU A 1 6   ? 146.243 115.059 127.176 1.00 143.67 ? 7   GLU A O   1 
ATOM   40   C CB  . GLU A 1 6   ? 143.726 113.105 127.449 1.00 153.68 ? 7   GLU A CB  1 
ATOM   41   C CG  . GLU A 1 6   ? 144.409 112.845 128.783 1.00 161.92 ? 7   GLU A CG  1 
ATOM   42   C CD  . GLU A 1 6   ? 144.123 111.458 129.325 1.00 162.95 ? 7   GLU A CD  1 
ATOM   43   O OE1 . GLU A 1 6   ? 143.406 110.691 128.649 1.00 159.20 ? 7   GLU A OE1 1 
ATOM   44   O OE2 . GLU A 1 6   ? 144.615 111.135 130.426 1.00 165.81 ? 7   GLU A OE2 1 
ATOM   45   N N   . LEU A 1 7   ? 145.602 114.454 125.107 1.00 139.17 ? 8   LEU A N   1 
ATOM   46   C CA  . LEU A 1 7   ? 146.952 114.554 124.565 1.00 136.44 ? 8   LEU A CA  1 
ATOM   47   C C   . LEU A 1 7   ? 147.371 115.986 124.258 1.00 138.05 ? 8   LEU A C   1 
ATOM   48   O O   . LEU A 1 7   ? 148.527 116.203 123.879 1.00 137.12 ? 8   LEU A O   1 
ATOM   49   C CB  . LEU A 1 7   ? 147.086 113.707 123.294 1.00 131.82 ? 8   LEU A CB  1 
ATOM   50   C CG  . LEU A 1 7   ? 146.783 112.206 123.339 1.00 124.42 ? 8   LEU A CG  1 
ATOM   51   C CD1 . LEU A 1 7   ? 145.349 111.900 122.934 1.00 126.90 ? 8   LEU A CD1 1 
ATOM   52   C CD2 . LEU A 1 7   ? 147.760 111.445 122.456 1.00 123.75 ? 8   LEU A CD2 1 
ATOM   53   N N   . PHE A 1 8   ? 146.476 116.960 124.403 1.00 136.23 ? 9   PHE A N   1 
ATOM   54   C CA  . PHE A 1 8   ? 146.766 118.340 124.040 1.00 133.22 ? 9   PHE A CA  1 
ATOM   55   C C   . PHE A 1 8   ? 147.027 119.240 125.238 1.00 136.51 ? 9   PHE A C   1 
ATOM   56   O O   . PHE A 1 8   ? 147.257 120.439 125.053 1.00 138.39 ? 9   PHE A O   1 
ATOM   57   C CB  . PHE A 1 8   ? 145.620 118.913 123.206 1.00 130.94 ? 9   PHE A CB  1 
ATOM   58   C CG  . PHE A 1 8   ? 145.828 118.774 121.732 1.00 133.08 ? 9   PHE A CG  1 
ATOM   59   C CD1 . PHE A 1 8   ? 145.482 117.602 121.084 1.00 130.14 ? 9   PHE A CD1 1 
ATOM   60   C CD2 . PHE A 1 8   ? 146.386 119.806 120.995 1.00 129.91 ? 9   PHE A CD2 1 
ATOM   61   C CE1 . PHE A 1 8   ? 145.679 117.464 119.729 1.00 125.66 ? 9   PHE A CE1 1 
ATOM   62   C CE2 . PHE A 1 8   ? 146.585 119.672 119.634 1.00 124.76 ? 9   PHE A CE2 1 
ATOM   63   C CZ  . PHE A 1 8   ? 146.230 118.500 119.001 1.00 122.45 ? 9   PHE A CZ  1 
ATOM   64   N N   . THR A 1 9   ? 146.997 118.705 126.453 1.00 137.75 ? 10  THR A N   1 
ATOM   65   C CA  . THR A 1 9   ? 147.265 119.502 127.647 1.00 137.68 ? 10  THR A CA  1 
ATOM   66   C C   . THR A 1 9   ? 148.771 119.687 127.767 1.00 135.09 ? 10  THR A C   1 
ATOM   67   O O   . THR A 1 9   ? 149.462 118.882 128.395 1.00 137.69 ? 10  THR A O   1 
ATOM   68   C CB  . THR A 1 9   ? 146.687 118.830 128.887 1.00 146.72 ? 10  THR A CB  1 
ATOM   69   O OG1 . THR A 1 9   ? 147.239 117.514 129.021 1.00 154.41 ? 10  THR A OG1 1 
ATOM   70   C CG2 . THR A 1 9   ? 145.172 118.730 128.779 1.00 146.81 ? 10  THR A CG2 1 
ATOM   71   N N   . GLY A 1 10  ? 149.287 120.752 127.160 1.00 133.73 ? 11  GLY A N   1 
ATOM   72   C CA  . GLY A 1 10  ? 150.710 121.024 127.205 1.00 130.49 ? 11  GLY A CA  1 
ATOM   73   C C   . GLY A 1 10  ? 151.272 121.494 125.881 1.00 127.27 ? 11  GLY A C   1 
ATOM   74   O O   . GLY A 1 10  ? 150.597 121.422 124.850 1.00 130.52 ? 11  GLY A O   1 
ATOM   75   N N   . VAL A 1 11  ? 152.512 121.980 125.897 1.00 124.69 ? 12  VAL A N   1 
ATOM   76   C CA  . VAL A 1 11  ? 153.147 122.461 124.678 1.00 129.23 ? 12  VAL A CA  1 
ATOM   77   C C   . VAL A 1 11  ? 153.606 121.271 123.847 1.00 125.00 ? 12  VAL A C   1 
ATOM   78   O O   . VAL A 1 11  ? 154.370 120.420 124.321 1.00 127.23 ? 12  VAL A O   1 
ATOM   79   C CB  . VAL A 1 11  ? 154.325 123.388 125.015 1.00 134.16 ? 12  VAL A CB  1 
ATOM   80   C CG1 . VAL A 1 11  ? 155.050 123.820 123.746 1.00 128.14 ? 12  VAL A CG1 1 
ATOM   81   C CG2 . VAL A 1 11  ? 153.850 124.593 125.812 1.00 136.76 ? 12  VAL A CG2 1 
ATOM   82   N N   . VAL A 1 12  ? 153.145 121.205 122.603 1.00 124.12 ? 13  VAL A N   1 
ATOM   83   C CA  . VAL A 1 12  ? 153.545 120.122 121.708 1.00 124.74 ? 13  VAL A CA  1 
ATOM   84   C C   . VAL A 1 12  ? 154.259 120.709 120.493 1.00 126.19 ? 13  VAL A C   1 
ATOM   85   O O   . VAL A 1 12  ? 153.911 121.810 120.036 1.00 131.21 ? 13  VAL A O   1 
ATOM   86   C CB  . VAL A 1 12  ? 152.338 119.254 121.308 1.00 128.50 ? 13  VAL A CB  1 
ATOM   87   C CG1 . VAL A 1 12  ? 151.848 118.455 122.504 1.00 125.21 ? 13  VAL A CG1 1 
ATOM   88   C CG2 . VAL A 1 12  ? 151.206 120.101 120.756 1.00 124.91 ? 13  VAL A CG2 1 
ATOM   89   N N   . PRO A 1 13  ? 155.276 120.034 119.959 1.00 124.09 ? 14  PRO A N   1 
ATOM   90   C CA  . PRO A 1 13  ? 155.993 120.568 118.795 1.00 128.48 ? 14  PRO A CA  1 
ATOM   91   C C   . PRO A 1 13  ? 155.151 120.488 117.530 1.00 133.95 ? 14  PRO A C   1 
ATOM   92   O O   . PRO A 1 13  ? 154.185 119.729 117.430 1.00 130.32 ? 14  PRO A O   1 
ATOM   93   C CB  . PRO A 1 13  ? 157.235 119.675 118.696 1.00 126.87 ? 14  PRO A CB  1 
ATOM   94   C CG  . PRO A 1 13  ? 157.356 119.021 120.034 1.00 125.52 ? 14  PRO A CG  1 
ATOM   95   C CD  . PRO A 1 13  ? 155.957 118.862 120.530 1.00 127.07 ? 14  PRO A CD  1 
ATOM   96   N N   . ILE A 1 14  ? 155.540 121.301 116.549 1.00 129.27 ? 15  ILE A N   1 
ATOM   97   C CA  . ILE A 1 14  ? 154.844 121.385 115.269 1.00 120.19 ? 15  ILE A CA  1 
ATOM   98   C C   . ILE A 1 14  ? 155.887 121.449 114.160 1.00 119.13 ? 15  ILE A C   1 
ATOM   99   O O   . ILE A 1 14  ? 156.996 121.960 114.354 1.00 121.60 ? 15  ILE A O   1 
ATOM   100  C CB  . ILE A 1 14  ? 153.858 122.584 115.251 1.00 122.68 ? 15  ILE A CB  1 
ATOM   101  C CG1 . ILE A 1 14  ? 152.752 122.409 114.214 1.00 125.81 ? 15  ILE A CG1 1 
ATOM   102  C CG2 . ILE A 1 14  ? 154.531 123.892 115.018 1.00 122.92 ? 15  ILE A CG2 1 
ATOM   103  C CD1 . ILE A 1 14  ? 151.942 121.222 114.397 1.00 123.90 ? 15  ILE A CD1 1 
ATOM   104  N N   . LEU A 1 15  ? 155.540 120.881 113.006 1.00 123.24 ? 16  LEU A N   1 
ATOM   105  C CA  . LEU A 1 15  ? 156.401 120.877 111.831 1.00 120.16 ? 16  LEU A CA  1 
ATOM   106  C C   . LEU A 1 15  ? 155.513 121.055 110.610 1.00 114.62 ? 16  LEU A C   1 
ATOM   107  O O   . LEU A 1 15  ? 154.437 120.456 110.533 1.00 119.49 ? 16  LEU A O   1 
ATOM   108  C CB  . LEU A 1 15  ? 157.217 119.576 111.747 1.00 122.16 ? 16  LEU A CB  1 
ATOM   109  C CG  . LEU A 1 15  ? 158.351 119.374 110.729 1.00 123.15 ? 16  LEU A CG  1 
ATOM   110  C CD1 . LEU A 1 15  ? 159.362 118.402 111.308 1.00 126.37 ? 16  LEU A CD1 1 
ATOM   111  C CD2 . LEU A 1 15  ? 157.873 118.847 109.378 1.00 119.29 ? 16  LEU A CD2 1 
ATOM   112  N N   . VAL A 1 16  ? 155.964 121.869 109.659 1.00 112.11 ? 17  VAL A N   1 
ATOM   113  C CA  . VAL A 1 16  ? 155.147 122.294 108.532 1.00 107.43 ? 17  VAL A CA  1 
ATOM   114  C C   . VAL A 1 16  ? 155.962 122.163 107.248 1.00 105.81 ? 17  VAL A C   1 
ATOM   115  O O   . VAL A 1 16  ? 157.175 122.403 107.237 1.00 109.41 ? 17  VAL A O   1 
ATOM   116  C CB  . VAL A 1 16  ? 154.606 123.731 108.757 1.00 110.24 ? 17  VAL A CB  1 
ATOM   117  C CG1 . VAL A 1 16  ? 155.721 124.773 108.842 1.00 117.31 ? 17  VAL A CG1 1 
ATOM   118  C CG2 . VAL A 1 16  ? 153.573 124.114 107.714 1.00 115.62 ? 17  VAL A CG2 1 
ATOM   119  N N   . GLU A 1 17  ? 155.299 121.720 106.178 1.00 108.80 ? 18  GLU A N   1 
ATOM   120  C CA  . GLU A 1 17  ? 155.926 121.486 104.886 1.00 113.11 ? 18  GLU A CA  1 
ATOM   121  C C   . GLU A 1 17  ? 154.939 121.862 103.791 1.00 114.31 ? 18  GLU A C   1 
ATOM   122  O O   . GLU A 1 17  ? 153.741 121.598 103.914 1.00 125.03 ? 18  GLU A O   1 
ATOM   123  C CB  . GLU A 1 17  ? 156.359 120.018 104.748 1.00 114.85 ? 18  GLU A CB  1 
ATOM   124  C CG  . GLU A 1 17  ? 157.106 119.681 103.470 1.00 121.65 ? 18  GLU A CG  1 
ATOM   125  C CD  . GLU A 1 17  ? 157.554 118.236 103.425 1.00 134.79 ? 18  GLU A CD  1 
ATOM   126  O OE1 . GLU A 1 17  ? 157.262 117.493 104.385 1.00 137.79 ? 18  GLU A OE1 1 
ATOM   127  O OE2 . GLU A 1 17  ? 158.197 117.843 102.429 1.00 140.58 ? 18  GLU A OE2 1 
ATOM   128  N N   . LEU A 1 18  ? 155.442 122.479 102.723 1.00 112.46 ? 19  LEU A N   1 
ATOM   129  C CA  . LEU A 1 18  ? 154.600 122.954 101.636 1.00 115.26 ? 19  LEU A CA  1 
ATOM   130  C C   . LEU A 1 18  ? 155.366 122.865 100.326 1.00 120.44 ? 19  LEU A C   1 
ATOM   131  O O   . LEU A 1 18  ? 156.514 123.310 100.241 1.00 128.05 ? 19  LEU A O   1 
ATOM   132  C CB  . LEU A 1 18  ? 154.151 124.399 101.885 1.00 121.95 ? 19  LEU A CB  1 
ATOM   133  C CG  . LEU A 1 18  ? 153.209 125.121 100.919 1.00 129.36 ? 19  LEU A CG  1 
ATOM   134  C CD1 . LEU A 1 18  ? 152.144 125.877 101.685 1.00 121.26 ? 19  LEU A CD1 1 
ATOM   135  C CD2 . LEU A 1 18  ? 153.991 126.084 100.036 1.00 127.22 ? 19  LEU A CD2 1 
ATOM   136  N N   . ASP A 1 19  ? 154.709 122.313 99.307  1.00 116.40 ? 20  ASP A N   1 
ATOM   137  C CA  . ASP A 1 19  ? 155.234 122.251 97.948  1.00 117.82 ? 20  ASP A CA  1 
ATOM   138  C C   . ASP A 1 19  ? 154.171 122.808 97.016  1.00 118.93 ? 20  ASP A C   1 
ATOM   139  O O   . ASP A 1 19  ? 153.120 122.186 96.836  1.00 126.02 ? 20  ASP A O   1 
ATOM   140  C CB  . ASP A 1 19  ? 155.586 120.813 97.556  1.00 122.92 ? 20  ASP A CB  1 
ATOM   141  C CG  . ASP A 1 19  ? 156.639 120.200 98.457  1.00 131.90 ? 20  ASP A CG  1 
ATOM   142  O OD1 . ASP A 1 19  ? 157.773 120.717 98.492  1.00 137.81 ? 20  ASP A OD1 1 
ATOM   143  O OD2 . ASP A 1 19  ? 156.330 119.196 99.133  1.00 132.72 ? 20  ASP A OD2 1 
ATOM   144  N N   . GLY A 1 20  ? 154.438 123.972 96.415  1.00 121.71 ? 21  GLY A N   1 
ATOM   145  C CA  . GLY A 1 20  ? 153.428 124.663 95.644  1.00 127.09 ? 21  GLY A CA  1 
ATOM   146  C C   . GLY A 1 20  ? 153.928 125.059 94.269  1.00 131.74 ? 21  GLY A C   1 
ATOM   147  O O   . GLY A 1 20  ? 155.127 125.020 93.977  1.00 134.02 ? 21  GLY A O   1 
ATOM   148  N N   . ASP A 1 21  ? 152.974 125.456 93.428  1.00 130.43 ? 22  ASP A N   1 
ATOM   149  C CA  . ASP A 1 21  ? 153.246 125.842 92.053  1.00 130.94 ? 22  ASP A CA  1 
ATOM   150  C C   . ASP A 1 21  ? 152.295 126.961 91.656  1.00 129.41 ? 22  ASP A C   1 
ATOM   151  O O   . ASP A 1 21  ? 151.076 126.817 91.777  1.00 133.12 ? 22  ASP A O   1 
ATOM   152  C CB  . ASP A 1 21  ? 153.075 124.647 91.105  1.00 135.60 ? 22  ASP A CB  1 
ATOM   153  C CG  . ASP A 1 21  ? 153.220 125.026 89.641  1.00 140.67 ? 22  ASP A CG  1 
ATOM   154  O OD1 . ASP A 1 21  ? 153.995 125.954 89.328  1.00 139.62 ? 22  ASP A OD1 1 
ATOM   155  O OD2 . ASP A 1 21  ? 152.552 124.391 88.799  1.00 142.44 ? 22  ASP A OD2 1 
ATOM   156  N N   . VAL A 1 22  ? 152.855 128.073 91.181  1.00 129.92 ? 23  VAL A N   1 
ATOM   157  C CA  . VAL A 1 22  ? 152.062 129.182 90.653  1.00 136.22 ? 23  VAL A CA  1 
ATOM   158  C C   . VAL A 1 22  ? 152.512 129.509 89.223  1.00 136.19 ? 23  VAL A C   1 
ATOM   159  O O   . VAL A 1 22  ? 153.652 129.938 89.002  1.00 137.81 ? 23  VAL A O   1 
ATOM   160  C CB  . VAL A 1 22  ? 152.087 130.426 91.571  1.00 136.76 ? 23  VAL A CB  1 
ATOM   161  C CG1 . VAL A 1 22  ? 151.356 130.120 92.850  1.00 129.79 ? 23  VAL A CG1 1 
ATOM   162  C CG2 . VAL A 1 22  ? 153.505 130.820 92.005  1.00 136.83 ? 23  VAL A CG2 1 
ATOM   163  N N   . ASN A 1 23  ? 151.619 129.264 88.255  1.00 131.66 ? 24  ASN A N   1 
ATOM   164  C CA  . ASN A 1 23  ? 151.807 129.560 86.826  1.00 142.51 ? 24  ASN A CA  1 
ATOM   165  C C   . ASN A 1 23  ? 153.072 128.917 86.252  1.00 148.01 ? 24  ASN A C   1 
ATOM   166  O O   . ASN A 1 23  ? 153.815 129.526 85.478  1.00 146.63 ? 24  ASN A O   1 
ATOM   167  C CB  . ASN A 1 23  ? 151.802 131.068 86.576  1.00 146.38 ? 24  ASN A CB  1 
ATOM   168  C CG  . ASN A 1 23  ? 150.439 131.684 86.786  1.00 143.21 ? 24  ASN A CG  1 
ATOM   169  O OD1 . ASN A 1 23  ? 149.419 131.116 86.398  1.00 140.14 ? 24  ASN A OD1 1 
ATOM   170  N ND2 . ASN A 1 23  ? 150.414 132.861 87.394  1.00 144.00 ? 24  ASN A ND2 1 
ATOM   171  N N   . GLY A 1 24  ? 153.317 127.668 86.641  1.00 145.68 ? 25  GLY A N   1 
ATOM   172  C CA  . GLY A 1 24  ? 154.508 126.964 86.216  1.00 145.69 ? 25  GLY A CA  1 
ATOM   173  C C   . GLY A 1 24  ? 155.749 127.252 87.031  1.00 147.57 ? 25  GLY A C   1 
ATOM   174  O O   . GLY A 1 24  ? 156.809 126.685 86.735  1.00 148.27 ? 25  GLY A O   1 
ATOM   175  N N   . HIS A 1 25  ? 155.656 128.111 88.043  1.00 143.38 ? 26  HIS A N   1 
ATOM   176  C CA  . HIS A 1 25  ? 156.771 128.431 88.923  1.00 138.99 ? 26  HIS A CA  1 
ATOM   177  C C   . HIS A 1 25  ? 156.662 127.578 90.180  1.00 136.06 ? 26  HIS A C   1 
ATOM   178  O O   . HIS A 1 25  ? 155.719 127.739 90.961  1.00 138.21 ? 26  HIS A O   1 
ATOM   179  C CB  . HIS A 1 25  ? 156.771 129.915 89.288  1.00 136.21 ? 26  HIS A CB  1 
ATOM   180  C CG  . HIS A 1 25  ? 156.896 130.827 88.109  1.00 139.04 ? 26  HIS A CG  1 
ATOM   181  N ND1 . HIS A 1 25  ? 155.819 131.182 87.326  1.00 142.67 ? 26  HIS A ND1 1 
ATOM   182  C CD2 . HIS A 1 25  ? 157.970 131.462 87.582  1.00 138.21 ? 26  HIS A CD2 1 
ATOM   183  C CE1 . HIS A 1 25  ? 156.224 131.994 86.366  1.00 148.56 ? 26  HIS A CE1 1 
ATOM   184  N NE2 . HIS A 1 25  ? 157.525 132.180 86.499  1.00 143.72 ? 26  HIS A NE2 1 
ATOM   185  N N   . LYS A 1 26  ? 157.615 126.672 90.366  1.00 133.29 ? 27  LYS A N   1 
ATOM   186  C CA  . LYS A 1 26  ? 157.624 125.787 91.519  1.00 134.66 ? 27  LYS A CA  1 
ATOM   187  C C   . LYS A 1 26  ? 158.293 126.471 92.702  1.00 134.10 ? 27  LYS A C   1 
ATOM   188  O O   . LYS A 1 26  ? 159.237 127.248 92.532  1.00 136.51 ? 27  LYS A O   1 
ATOM   189  C CB  . LYS A 1 26  ? 158.357 124.485 91.192  1.00 134.82 ? 27  LYS A CB  1 
ATOM   190  C CG  . LYS A 1 26  ? 157.723 123.672 90.078  1.00 132.00 ? 27  LYS A CG  1 
ATOM   191  C CD  . LYS A 1 26  ? 156.379 123.114 90.500  1.00 133.78 ? 27  LYS A CD  1 
ATOM   192  C CE  . LYS A 1 26  ? 155.780 122.235 89.415  1.00 146.21 ? 27  LYS A CE  1 
ATOM   193  N NZ  . LYS A 1 26  ? 154.439 121.712 89.799  1.00 155.09 ? 27  LYS A NZ  1 
ATOM   194  N N   . PHE A 1 27  ? 157.798 126.177 93.903  1.00 132.16 ? 28  PHE A N   1 
ATOM   195  C CA  . PHE A 1 27  ? 158.409 126.659 95.132  1.00 132.65 ? 28  PHE A CA  1 
ATOM   196  C C   . PHE A 1 27  ? 158.077 125.687 96.254  1.00 127.22 ? 28  PHE A C   1 
ATOM   197  O O   . PHE A 1 27  ? 157.172 124.859 96.139  1.00 132.83 ? 28  PHE A O   1 
ATOM   198  C CB  . PHE A 1 27  ? 157.962 128.097 95.469  1.00 134.84 ? 28  PHE A CB  1 
ATOM   199  C CG  . PHE A 1 27  ? 156.484 128.248 95.725  1.00 130.97 ? 28  PHE A CG  1 
ATOM   200  C CD1 . PHE A 1 27  ? 155.613 128.504 94.677  1.00 133.29 ? 28  PHE A CD1 1 
ATOM   201  C CD2 . PHE A 1 27  ? 155.974 128.202 97.016  1.00 130.32 ? 28  PHE A CD2 1 
ATOM   202  C CE1 . PHE A 1 27  ? 154.257 128.661 94.903  1.00 137.17 ? 28  PHE A CE1 1 
ATOM   203  C CE2 . PHE A 1 27  ? 154.620 128.359 97.249  1.00 133.55 ? 28  PHE A CE2 1 
ATOM   204  C CZ  . PHE A 1 27  ? 153.761 128.590 96.191  1.00 133.48 ? 28  PHE A CZ  1 
ATOM   205  N N   . SER A 1 28  ? 158.833 125.787 97.344  1.00 119.25 ? 29  SER A N   1 
ATOM   206  C CA  . SER A 1 28  ? 158.655 124.897 98.482  1.00 117.00 ? 29  SER A CA  1 
ATOM   207  C C   . SER A 1 28  ? 159.164 125.581 99.738  1.00 117.36 ? 29  SER A C   1 
ATOM   208  O O   . SER A 1 28  ? 160.238 126.187 99.722  1.00 127.23 ? 29  SER A O   1 
ATOM   209  C CB  . SER A 1 28  ? 159.393 123.573 98.265  1.00 119.47 ? 29  SER A CB  1 
ATOM   210  O OG  . SER A 1 28  ? 160.794 123.771 98.222  1.00 128.57 ? 29  SER A OG  1 
ATOM   211  N N   . VAL A 1 29  ? 158.393 125.486 100.823 1.00 111.03 ? 30  VAL A N   1 
ATOM   212  C CA  . VAL A 1 29  ? 158.812 126.020 102.113 1.00 115.47 ? 30  VAL A CA  1 
ATOM   213  C C   . VAL A 1 29  ? 158.655 124.932 103.168 1.00 114.22 ? 30  VAL A C   1 
ATOM   214  O O   . VAL A 1 29  ? 157.908 123.966 102.998 1.00 119.16 ? 30  VAL A O   1 
ATOM   215  C CB  . VAL A 1 29  ? 158.034 127.295 102.532 1.00 117.69 ? 30  VAL A CB  1 
ATOM   216  C CG1 . VAL A 1 29  ? 158.240 128.430 101.533 1.00 120.67 ? 30  VAL A CG1 1 
ATOM   217  C CG2 . VAL A 1 29  ? 156.565 127.008 102.712 1.00 115.79 ? 30  VAL A CG2 1 
ATOM   218  N N   . SER A 1 30  ? 159.402 125.083 104.258 1.00 109.84 ? 31  SER A N   1 
ATOM   219  C CA  . SER A 1 30  ? 159.353 124.142 105.369 1.00 108.61 ? 31  SER A CA  1 
ATOM   220  C C   . SER A 1 30  ? 159.677 124.894 106.650 1.00 109.38 ? 31  SER A C   1 
ATOM   221  O O   . SER A 1 30  ? 160.223 126.000 106.616 1.00 116.70 ? 31  SER A O   1 
ATOM   222  C CB  . SER A 1 30  ? 160.326 122.969 105.178 1.00 109.50 ? 31  SER A CB  1 
ATOM   223  O OG  . SER A 1 30  ? 160.261 122.417 103.873 1.00 106.19 ? 31  SER A OG  1 
ATOM   224  N N   . GLY A 1 31  ? 159.333 124.288 107.781 1.00 109.82 ? 32  GLY A N   1 
ATOM   225  C CA  . GLY A 1 31  ? 159.647 124.920 109.051 1.00 111.22 ? 32  GLY A CA  1 
ATOM   226  C C   . GLY A 1 31  ? 159.196 124.090 110.231 1.00 112.89 ? 32  GLY A C   1 
ATOM   227  O O   . GLY A 1 31  ? 158.553 123.049 110.082 1.00 119.46 ? 32  GLY A O   1 
ATOM   228  N N   . GLU A 1 32  ? 159.550 124.576 111.420 1.00 112.63 ? 33  GLU A N   1 
ATOM   229  C CA  . GLU A 1 32  ? 159.193 123.944 112.683 1.00 115.35 ? 33  GLU A CA  1 
ATOM   230  C C   . GLU A 1 32  ? 158.704 125.007 113.659 1.00 112.70 ? 33  GLU A C   1 
ATOM   231  O O   . GLU A 1 32  ? 158.713 126.204 113.366 1.00 117.81 ? 33  GLU A O   1 
ATOM   232  C CB  . GLU A 1 32  ? 160.376 123.177 113.299 1.00 126.41 ? 33  GLU A CB  1 
ATOM   233  C CG  . GLU A 1 32  ? 160.845 121.950 112.521 1.00 133.97 ? 33  GLU A CG  1 
ATOM   234  C CD  . GLU A 1 32  ? 161.819 122.284 111.403 1.00 140.76 ? 33  GLU A CD  1 
ATOM   235  O OE1 . GLU A 1 32  ? 162.196 123.467 111.266 1.00 141.21 ? 33  GLU A OE1 1 
ATOM   236  O OE2 . GLU A 1 32  ? 162.208 121.359 110.659 1.00 141.98 ? 33  GLU A OE2 1 
ATOM   237  N N   . GLY A 1 33  ? 158.276 124.556 114.834 1.00 112.09 ? 34  GLY A N   1 
ATOM   238  C CA  . GLY A 1 33  ? 157.854 125.484 115.868 1.00 115.48 ? 34  GLY A CA  1 
ATOM   239  C C   . GLY A 1 33  ? 157.175 124.749 117.007 1.00 124.24 ? 34  GLY A C   1 
ATOM   240  O O   . GLY A 1 33  ? 157.315 123.533 117.146 1.00 124.15 ? 34  GLY A O   1 
ATOM   241  N N   . GLU A 1 34  ? 156.378 125.491 117.776 1.00 126.16 ? 35  GLU A N   1 
ATOM   242  C CA  . GLU A 1 34  ? 155.707 124.889 118.922 1.00 121.19 ? 35  GLU A CA  1 
ATOM   243  C C   . GLU A 1 34  ? 154.315 125.477 119.100 1.00 120.48 ? 35  GLU A C   1 
ATOM   244  O O   . GLU A 1 34  ? 154.091 126.671 118.886 1.00 128.82 ? 35  GLU A O   1 
ATOM   245  C CB  . GLU A 1 34  ? 156.518 125.055 120.226 1.00 127.89 ? 35  GLU A CB  1 
ATOM   246  C CG  . GLU A 1 34  ? 156.820 126.491 120.672 1.00 129.99 ? 35  GLU A CG  1 
ATOM   247  C CD  . GLU A 1 34  ? 157.986 127.123 119.934 1.00 134.46 ? 35  GLU A CD  1 
ATOM   248  O OE1 . GLU A 1 34  ? 158.783 126.376 119.328 1.00 135.59 ? 35  GLU A OE1 1 
ATOM   249  O OE2 . GLU A 1 34  ? 158.104 128.366 119.961 1.00 136.31 ? 35  GLU A OE2 1 
ATOM   250  N N   . GLY A 1 35  ? 153.377 124.627 119.513 1.00 116.09 ? 36  GLY A N   1 
ATOM   251  C CA  . GLY A 1 35  ? 152.021 125.078 119.746 1.00 120.79 ? 36  GLY A CA  1 
ATOM   252  C C   . GLY A 1 35  ? 151.436 124.513 121.020 1.00 118.54 ? 36  GLY A C   1 
ATOM   253  O O   . GLY A 1 35  ? 151.628 123.335 121.327 1.00 124.58 ? 36  GLY A O   1 
ATOM   254  N N   . ASP A 1 36  ? 150.732 125.346 121.780 1.00 118.29 ? 37  ASP A N   1 
ATOM   255  C CA  . ASP A 1 36  ? 150.068 124.926 123.004 1.00 123.35 ? 37  ASP A CA  1 
ATOM   256  C C   . ASP A 1 36  ? 148.584 125.228 122.855 1.00 126.61 ? 37  ASP A C   1 
ATOM   257  O O   . ASP A 1 36  ? 148.209 126.344 122.480 1.00 131.41 ? 37  ASP A O   1 
ATOM   258  C CB  . ASP A 1 36  ? 150.653 125.651 124.221 1.00 135.47 ? 37  ASP A CB  1 
ATOM   259  C CG  . ASP A 1 36  ? 150.181 125.069 125.554 1.00 140.93 ? 37  ASP A CG  1 
ATOM   260  O OD1 . ASP A 1 36  ? 149.380 124.110 125.570 1.00 137.62 ? 37  ASP A OD1 1 
ATOM   261  O OD2 . ASP A 1 36  ? 150.628 125.580 126.603 1.00 145.99 ? 37  ASP A OD2 1 
ATOM   262  N N   . ALA A 1 37  ? 147.748 124.236 123.145 1.00 127.59 ? 38  ALA A N   1 
ATOM   263  C CA  . ALA A 1 37  ? 146.309 124.377 122.994 1.00 125.53 ? 38  ALA A CA  1 
ATOM   264  C C   . ALA A 1 37  ? 145.582 124.578 124.314 1.00 129.52 ? 38  ALA A C   1 
ATOM   265  O O   . ALA A 1 37  ? 144.350 124.675 124.310 1.00 134.72 ? 38  ALA A O   1 
ATOM   266  C CB  . ALA A 1 37  ? 145.730 123.153 122.280 1.00 124.10 ? 38  ALA A CB  1 
ATOM   267  N N   . THR A 1 38  ? 146.306 124.615 125.436 1.00 136.54 ? 39  THR A N   1 
ATOM   268  C CA  . THR A 1 38  ? 145.670 124.878 126.723 1.00 145.13 ? 39  THR A CA  1 
ATOM   269  C C   . THR A 1 38  ? 145.150 126.310 126.791 1.00 143.92 ? 39  THR A C   1 
ATOM   270  O O   . THR A 1 38  ? 144.027 126.553 127.251 1.00 139.61 ? 39  THR A O   1 
ATOM   271  C CB  . THR A 1 38  ? 146.655 124.596 127.861 1.00 143.43 ? 39  THR A CB  1 
ATOM   272  O OG1 . THR A 1 38  ? 147.097 123.234 127.784 1.00 136.07 ? 39  THR A OG1 1 
ATOM   273  C CG2 . THR A 1 38  ? 146.004 124.822 129.219 1.00 144.60 ? 39  THR A CG2 1 
ATOM   274  N N   . TYR A 1 39  ? 145.939 127.271 126.300 1.00 138.98 ? 40  TYR A N   1 
ATOM   275  C CA  . TYR A 1 39  ? 145.511 128.664 126.254 1.00 142.89 ? 40  TYR A CA  1 
ATOM   276  C C   . TYR A 1 39  ? 145.596 129.245 124.844 1.00 140.35 ? 40  TYR A C   1 
ATOM   277  O O   . TYR A 1 39  ? 145.524 130.467 124.680 1.00 139.60 ? 40  TYR A O   1 
ATOM   278  C CB  . TYR A 1 39  ? 146.310 129.509 127.254 1.00 146.34 ? 40  TYR A CB  1 
ATOM   279  C CG  . TYR A 1 39  ? 147.804 129.573 127.014 1.00 149.89 ? 40  TYR A CG  1 
ATOM   280  C CD1 . TYR A 1 39  ? 148.655 128.626 127.574 1.00 146.22 ? 40  TYR A CD1 1 
ATOM   281  C CD2 . TYR A 1 39  ? 148.369 130.605 126.269 1.00 152.84 ? 40  TYR A CD2 1 
ATOM   282  C CE1 . TYR A 1 39  ? 150.023 128.685 127.370 1.00 155.74 ? 40  TYR A CE1 1 
ATOM   283  C CE2 . TYR A 1 39  ? 149.736 130.671 126.060 1.00 158.16 ? 40  TYR A CE2 1 
ATOM   284  C CZ  . TYR A 1 39  ? 150.557 129.709 126.614 1.00 161.11 ? 40  TYR A CZ  1 
ATOM   285  O OH  . TYR A 1 39  ? 151.917 129.772 126.411 1.00 158.71 ? 40  TYR A OH  1 
ATOM   286  N N   . GLY A 1 40  ? 145.739 128.395 123.828 1.00 136.78 ? 41  GLY A N   1 
ATOM   287  C CA  . GLY A 1 40  ? 145.626 128.812 122.442 1.00 123.02 ? 41  GLY A CA  1 
ATOM   288  C C   . GLY A 1 40  ? 146.741 129.690 121.912 1.00 117.95 ? 41  GLY A C   1 
ATOM   289  O O   . GLY A 1 40  ? 146.496 130.835 121.525 1.00 118.65 ? 41  GLY A O   1 
ATOM   290  N N   . LYS A 1 41  ? 147.967 129.175 121.886 1.00 119.35 ? 42  LYS A N   1 
ATOM   291  C CA  . LYS A 1 41  ? 149.112 129.898 121.352 1.00 121.46 ? 42  LYS A CA  1 
ATOM   292  C C   . LYS A 1 41  ? 149.836 129.035 120.329 1.00 118.49 ? 42  LYS A C   1 
ATOM   293  O O   . LYS A 1 41  ? 149.929 127.814 120.490 1.00 123.34 ? 42  LYS A O   1 
ATOM   294  C CB  . LYS A 1 41  ? 150.079 130.307 122.465 1.00 125.88 ? 42  LYS A CB  1 
ATOM   295  C CG  . LYS A 1 41  ? 150.890 131.551 122.151 1.00 129.95 ? 42  LYS A CG  1 
ATOM   296  C CD  . LYS A 1 41  ? 151.861 131.876 123.271 1.00 139.64 ? 42  LYS A CD  1 
ATOM   297  C CE  . LYS A 1 41  ? 153.132 131.053 123.154 1.00 139.70 ? 42  LYS A CE  1 
ATOM   298  N NZ  . LYS A 1 41  ? 153.750 131.175 121.805 1.00 127.13 ? 42  LYS A NZ  1 
ATOM   299  N N   . LEU A 1 42  ? 150.343 129.667 119.274 1.00 112.74 ? 43  LEU A N   1 
ATOM   300  C CA  . LEU A 1 42  ? 151.070 128.924 118.252 1.00 114.67 ? 43  LEU A CA  1 
ATOM   301  C C   . LEU A 1 42  ? 152.209 129.772 117.707 1.00 116.28 ? 43  LEU A C   1 
ATOM   302  O O   . LEU A 1 42  ? 151.991 130.921 117.316 1.00 119.89 ? 43  LEU A O   1 
ATOM   303  C CB  . LEU A 1 42  ? 150.130 128.502 117.118 1.00 117.12 ? 43  LEU A CB  1 
ATOM   304  C CG  . LEU A 1 42  ? 150.772 128.012 115.823 1.00 118.11 ? 43  LEU A CG  1 
ATOM   305  C CD1 . LEU A 1 42  ? 151.328 126.611 116.004 1.00 115.56 ? 43  LEU A CD1 1 
ATOM   306  C CD2 . LEU A 1 42  ? 149.764 128.055 114.690 1.00 115.52 ? 43  LEU A CD2 1 
ATOM   307  N N   . THR A 1 43  ? 153.415 129.205 117.681 1.00 114.93 ? 44  THR A N   1 
ATOM   308  C CA  . THR A 1 43  ? 154.592 129.859 117.129 1.00 113.82 ? 44  THR A CA  1 
ATOM   309  C C   . THR A 1 43  ? 155.123 129.018 115.979 1.00 113.42 ? 44  THR A C   1 
ATOM   310  O O   . THR A 1 43  ? 155.493 127.851 116.174 1.00 120.58 ? 44  THR A O   1 
ATOM   311  C CB  . THR A 1 43  ? 155.678 130.047 118.191 1.00 122.51 ? 44  THR A CB  1 
ATOM   312  O OG1 . THR A 1 43  ? 155.170 130.858 119.258 1.00 132.37 ? 44  THR A OG1 1 
ATOM   313  C CG2 . THR A 1 43  ? 156.901 130.718 117.588 1.00 116.72 ? 44  THR A CG2 1 
ATOM   314  N N   . LEU A 1 44  ? 155.167 129.622 114.792 1.00 116.46 ? 45  LEU A N   1 
ATOM   315  C CA  . LEU A 1 44  ? 155.527 128.940 113.553 1.00 111.69 ? 45  LEU A CA  1 
ATOM   316  C C   . LEU A 1 44  ? 156.662 129.703 112.888 1.00 115.89 ? 45  LEU A C   1 
ATOM   317  O O   . LEU A 1 44  ? 156.538 130.903 112.633 1.00 122.87 ? 45  LEU A O   1 
ATOM   318  C CB  . LEU A 1 44  ? 154.315 128.849 112.618 1.00 113.79 ? 45  LEU A CB  1 
ATOM   319  C CG  . LEU A 1 44  ? 154.182 127.664 111.661 1.00 113.66 ? 45  LEU A CG  1 
ATOM   320  C CD1 . LEU A 1 44  ? 154.059 126.392 112.423 1.00 118.48 ? 45  LEU A CD1 1 
ATOM   321  C CD2 . LEU A 1 44  ? 152.966 127.827 110.770 1.00 110.00 ? 45  LEU A CD2 1 
ATOM   322  N N   . LYS A 1 45  ? 157.762 129.018 112.606 1.00 111.63 ? 46  LYS A N   1 
ATOM   323  C CA  . LYS A 1 45  ? 158.920 129.636 111.968 1.00 112.67 ? 46  LYS A CA  1 
ATOM   324  C C   . LYS A 1 45  ? 159.093 128.999 110.595 1.00 114.87 ? 46  LYS A C   1 
ATOM   325  O O   . LYS A 1 45  ? 159.478 127.831 110.495 1.00 120.26 ? 46  LYS A O   1 
ATOM   326  C CB  . LYS A 1 45  ? 160.170 129.464 112.832 1.00 118.04 ? 46  LYS A CB  1 
ATOM   327  C CG  . LYS A 1 45  ? 161.486 129.876 112.174 1.00 120.64 ? 46  LYS A CG  1 
ATOM   328  C CD  . LYS A 1 45  ? 161.459 131.316 111.678 1.00 123.10 ? 46  LYS A CD  1 
ATOM   329  C CE  . LYS A 1 45  ? 162.837 131.774 111.227 1.00 127.09 ? 46  LYS A CE  1 
ATOM   330  N NZ  . LYS A 1 45  ? 163.716 132.122 112.379 1.00 131.94 ? 46  LYS A NZ  1 
ATOM   331  N N   . LEU A 1 46  ? 158.813 129.763 109.544 1.00 112.21 ? 47  LEU A N   1 
ATOM   332  C CA  . LEU A 1 46  ? 158.931 129.284 108.172 1.00 111.14 ? 47  LEU A CA  1 
ATOM   333  C C   . LEU A 1 46  ? 160.264 129.717 107.583 1.00 115.02 ? 47  LEU A C   1 
ATOM   334  O O   . LEU A 1 46  ? 160.718 130.840 107.821 1.00 122.74 ? 47  LEU A O   1 
ATOM   335  C CB  . LEU A 1 46  ? 157.794 129.802 107.287 1.00 114.37 ? 47  LEU A CB  1 
ATOM   336  C CG  . LEU A 1 46  ? 156.443 129.083 107.210 1.00 114.43 ? 47  LEU A CG  1 
ATOM   337  C CD1 . LEU A 1 46  ? 156.622 127.690 106.626 1.00 107.90 ? 47  LEU A CD1 1 
ATOM   338  C CD2 . LEU A 1 46  ? 155.715 129.030 108.537 1.00 115.03 ? 47  LEU A CD2 1 
ATOM   339  N N   . ILE A 1 47  ? 160.887 128.822 106.821 1.00 111.86 ? 48  ILE A N   1 
ATOM   340  C CA  . ILE A 1 47  ? 162.094 129.126 106.062 1.00 115.68 ? 48  ILE A CA  1 
ATOM   341  C C   . ILE A 1 47  ? 161.867 128.634 104.640 1.00 115.71 ? 48  ILE A C   1 
ATOM   342  O O   . ILE A 1 47  ? 161.556 127.456 104.433 1.00 116.56 ? 48  ILE A O   1 
ATOM   343  C CB  . ILE A 1 47  ? 163.361 128.480 106.658 1.00 120.42 ? 48  ILE A CB  1 
ATOM   344  C CG1 . ILE A 1 47  ? 163.682 128.998 108.070 1.00 122.94 ? 48  ILE A CG1 1 
ATOM   345  C CG2 . ILE A 1 47  ? 164.551 128.721 105.753 1.00 124.70 ? 48  ILE A CG2 1 
ATOM   346  C CD1 . ILE A 1 47  ? 163.080 128.193 109.220 1.00 118.47 ? 48  ILE A CD1 1 
ATOM   347  N N   . CYS A 1 48  ? 162.014 129.530 103.667 1.00 121.66 ? 49  CYS A N   1 
ATOM   348  C CA  . CYS A 1 48  ? 161.860 129.147 102.270 1.00 127.30 ? 49  CYS A CA  1 
ATOM   349  C C   . CYS A 1 48  ? 163.040 128.290 101.830 1.00 128.84 ? 49  CYS A C   1 
ATOM   350  O O   . CYS A 1 48  ? 164.199 128.633 102.083 1.00 134.98 ? 49  CYS A O   1 
ATOM   351  C CB  . CYS A 1 48  ? 161.745 130.391 101.391 1.00 137.10 ? 49  CYS A CB  1 
ATOM   352  S SG  . CYS A 1 48  ? 161.536 130.044 99.632  1.00 156.43 ? 49  CYS A SG  1 
ATOM   353  N N   . THR A 1 49  ? 162.745 127.172 101.168 1.00 125.77 ? 50  THR A N   1 
ATOM   354  C CA  . THR A 1 49  ? 163.785 126.215 100.812 1.00 133.79 ? 50  THR A CA  1 
ATOM   355  C C   . THR A 1 49  ? 164.403 126.479 99.447  1.00 136.10 ? 50  THR A C   1 
ATOM   356  O O   . THR A 1 49  ? 165.596 126.215 99.259  1.00 139.29 ? 50  THR A O   1 
ATOM   357  C CB  . THR A 1 49  ? 163.229 124.789 100.844 1.00 134.99 ? 50  THR A CB  1 
ATOM   358  O OG1 . THR A 1 49  ? 162.174 124.664 99.883  1.00 140.73 ? 50  THR A OG1 1 
ATOM   359  C CG2 . THR A 1 49  ? 162.690 124.459 102.227 1.00 127.68 ? 50  THR A CG2 1 
ATOM   360  N N   . THR A 1 50  ? 163.630 126.990 98.490  1.00 134.77 ? 51  THR A N   1 
ATOM   361  C CA  . THR A 1 50  ? 164.166 127.248 97.160  1.00 145.32 ? 51  THR A CA  1 
ATOM   362  C C   . THR A 1 50  ? 164.896 128.582 97.058  1.00 153.64 ? 51  THR A C   1 
ATOM   363  O O   . THR A 1 50  ? 165.482 128.868 96.008  1.00 154.87 ? 51  THR A O   1 
ATOM   364  C CB  . THR A 1 50  ? 163.048 127.191 96.115  1.00 148.73 ? 51  THR A CB  1 
ATOM   365  O OG1 . THR A 1 50  ? 163.579 127.519 94.825  1.00 157.08 ? 51  THR A OG1 1 
ATOM   366  C CG2 . THR A 1 50  ? 161.939 128.163 96.465  1.00 143.80 ? 51  THR A CG2 1 
ATOM   367  N N   . GLY A 1 51  ? 164.875 129.400 98.111  1.00 152.84 ? 52  GLY A N   1 
ATOM   368  C CA  . GLY A 1 51  ? 165.653 130.615 98.180  1.00 155.31 ? 52  GLY A CA  1 
ATOM   369  C C   . GLY A 1 51  ? 164.905 131.881 97.813  1.00 159.43 ? 52  GLY A C   1 
ATOM   370  O O   . GLY A 1 51  ? 165.349 132.973 98.187  1.00 160.89 ? 52  GLY A O   1 
ATOM   371  N N   . LYS A 1 52  ? 163.787 131.769 97.099  1.00 157.99 ? 53  LYS A N   1 
ATOM   372  C CA  . LYS A 1 52  ? 163.016 132.940 96.709  1.00 156.69 ? 53  LYS A CA  1 
ATOM   373  C C   . LYS A 1 52  ? 161.552 132.547 96.573  1.00 152.96 ? 53  LYS A C   1 
ATOM   374  O O   . LYS A 1 52  ? 161.223 131.400 96.264  1.00 155.78 ? 53  LYS A O   1 
ATOM   375  C CB  . LYS A 1 52  ? 163.574 133.570 95.417  1.00 160.28 ? 53  LYS A CB  1 
ATOM   376  C CG  . LYS A 1 52  ? 163.667 132.653 94.186  1.00 159.88 ? 53  LYS A CG  1 
ATOM   377  C CD  . LYS A 1 52  ? 162.448 132.725 93.266  1.00 157.34 ? 53  LYS A CD  1 
ATOM   378  C CE  . LYS A 1 52  ? 162.617 131.821 92.056  1.00 164.16 ? 53  LYS A CE  1 
ATOM   379  N NZ  . LYS A 1 52  ? 161.527 132.016 91.061  1.00 161.65 ? 53  LYS A NZ  1 
ATOM   380  N N   . LEU A 1 53  ? 160.674 133.521 96.798  1.00 143.41 ? 54  LEU A N   1 
ATOM   381  C CA  . LEU A 1 53  ? 159.242 133.286 96.753  1.00 137.32 ? 54  LEU A CA  1 
ATOM   382  C C   . LEU A 1 53  ? 158.614 134.201 95.708  1.00 138.71 ? 54  LEU A C   1 
ATOM   383  O O   . LEU A 1 53  ? 158.753 135.433 95.799  1.00 142.38 ? 54  LEU A O   1 
ATOM   384  C CB  . LEU A 1 53  ? 158.600 133.525 98.125  1.00 139.64 ? 54  LEU A CB  1 
ATOM   385  C CG  . LEU A 1 53  ? 157.439 132.601 98.498  1.00 145.66 ? 54  LEU A CG  1 
ATOM   386  C CD1 . LEU A 1 53  ? 157.831 131.141 98.328  1.00 143.96 ? 54  LEU A CD1 1 
ATOM   387  C CD2 . LEU A 1 53  ? 156.959 132.874 99.915  1.00 135.79 ? 54  LEU A CD2 1 
ATOM   388  N N   . PRO A 1 54  ? 157.925 133.649 94.703  1.00 136.84 ? 55  PRO A N   1 
ATOM   389  C CA  . PRO A 1 54  ? 157.217 134.501 93.737  1.00 134.39 ? 55  PRO A CA  1 
ATOM   390  C C   . PRO A 1 54  ? 155.918 135.083 94.266  1.00 133.29 ? 55  PRO A C   1 
ATOM   391  O O   . PRO A 1 54  ? 155.334 135.948 93.598  1.00 135.68 ? 55  PRO A O   1 
ATOM   392  C CB  . PRO A 1 54  ? 156.948 133.545 92.569  1.00 134.76 ? 55  PRO A CB  1 
ATOM   393  C CG  . PRO A 1 54  ? 156.860 132.204 93.214  1.00 136.81 ? 55  PRO A CG  1 
ATOM   394  C CD  . PRO A 1 54  ? 157.855 132.223 94.340  1.00 140.28 ? 55  PRO A CD  1 
ATOM   395  N N   . VAL A 1 55  ? 155.450 134.641 95.428  1.00 126.56 ? 56  VAL A N   1 
ATOM   396  C CA  . VAL A 1 55  ? 154.201 135.129 96.009  1.00 122.41 ? 56  VAL A CA  1 
ATOM   397  C C   . VAL A 1 55  ? 154.523 135.790 97.343  1.00 123.82 ? 56  VAL A C   1 
ATOM   398  O O   . VAL A 1 55  ? 155.545 135.475 97.975  1.00 131.11 ? 56  VAL A O   1 
ATOM   399  C CB  . VAL A 1 55  ? 153.168 133.986 96.174  1.00 119.25 ? 56  VAL A CB  1 
ATOM   400  C CG1 . VAL A 1 55  ? 152.796 133.413 94.819  1.00 127.28 ? 56  VAL A CG1 1 
ATOM   401  C CG2 . VAL A 1 55  ? 153.713 132.893 97.077  1.00 125.90 ? 56  VAL A CG2 1 
ATOM   402  N N   . PRO A 1 56  ? 153.701 136.745 97.779  1.00 114.33 ? 57  PRO A N   1 
ATOM   403  C CA  . PRO A 1 56  ? 153.903 137.328 99.110  1.00 111.85 ? 57  PRO A CA  1 
ATOM   404  C C   . PRO A 1 56  ? 153.559 136.348 100.221 1.00 113.36 ? 57  PRO A C   1 
ATOM   405  O O   . PRO A 1 56  ? 152.769 135.416 100.055 1.00 113.02 ? 57  PRO A O   1 
ATOM   406  C CB  . PRO A 1 56  ? 152.960 138.537 99.125  1.00 112.00 ? 57  PRO A CB  1 
ATOM   407  C CG  . PRO A 1 56  ? 152.647 138.807 97.700  1.00 117.52 ? 57  PRO A CG  1 
ATOM   408  C CD  . PRO A 1 56  ? 152.677 137.483 97.021  1.00 118.06 ? 57  PRO A CD  1 
ATOM   409  N N   . TRP A 1 57  ? 154.197 136.573 101.369 1.00 115.26 ? 58  TRP A N   1 
ATOM   410  C CA  . TRP A 1 57  ? 153.969 135.741 102.551 1.00 111.31 ? 58  TRP A CA  1 
ATOM   411  C C   . TRP A 1 57  ? 152.548 135.777 103.125 1.00 103.74 ? 58  TRP A C   1 
ATOM   412  O O   . TRP A 1 57  ? 152.065 134.702 103.521 1.00 104.09 ? 58  TRP A O   1 
ATOM   413  C CB  . TRP A 1 57  ? 155.016 136.079 103.621 1.00 121.28 ? 58  TRP A CB  1 
ATOM   414  C CG  . TRP A 1 57  ? 156.401 135.665 103.236 1.00 127.67 ? 58  TRP A CG  1 
ATOM   415  C CD1 . TRP A 1 57  ? 157.370 136.452 102.687 1.00 129.34 ? 58  TRP A CD1 1 
ATOM   416  C CD2 . TRP A 1 57  ? 156.969 134.356 103.361 1.00 126.57 ? 58  TRP A CD2 1 
ATOM   417  N NE1 . TRP A 1 57  ? 158.509 135.715 102.467 1.00 132.96 ? 58  TRP A NE1 1 
ATOM   418  C CE2 . TRP A 1 57  ? 158.288 134.425 102.873 1.00 129.69 ? 58  TRP A CE2 1 
ATOM   419  C CE3 . TRP A 1 57  ? 156.491 133.134 103.841 1.00 124.19 ? 58  TRP A CE3 1 
ATOM   420  C CZ2 . TRP A 1 57  ? 159.133 133.319 102.850 1.00 132.74 ? 58  TRP A CZ2 1 
ATOM   421  C CZ3 . TRP A 1 57  ? 157.332 132.038 103.817 1.00 124.53 ? 58  TRP A CZ3 1 
ATOM   422  C CH2 . TRP A 1 57  ? 158.638 132.138 103.326 1.00 126.60 ? 58  TRP A CH2 1 
ATOM   423  N N   . PRO A 1 58  ? 151.839 136.925 103.251 1.00 104.34 ? 59  PRO A N   1 
ATOM   424  C CA  . PRO A 1 58  ? 150.471 136.848 103.812 1.00 101.09 ? 59  PRO A CA  1 
ATOM   425  C C   . PRO A 1 58  ? 149.459 136.094 102.960 1.00 101.99 ? 59  PRO A C   1 
ATOM   426  O O   . PRO A 1 58  ? 148.398 135.723 103.477 1.00 99.89  ? 59  PRO A O   1 
ATOM   427  C CB  . PRO A 1 58  ? 150.066 138.320 103.969 1.00 100.04 ? 59  PRO A CB  1 
ATOM   428  C CG  . PRO A 1 58  ? 151.310 139.044 104.080 1.00 100.52 ? 59  PRO A CG  1 
ATOM   429  C CD  . PRO A 1 58  ? 152.260 138.343 103.176 1.00 104.21 ? 59  PRO A CD  1 
ATOM   430  N N   . THR A 1 59  ? 149.743 135.857 101.678 1.00 101.73 ? 60  THR A N   1 
ATOM   431  C CA  . THR A 1 59  ? 148.848 135.032 100.874 1.00 97.30  ? 60  THR A CA  1 
ATOM   432  C C   . THR A 1 59  ? 148.916 133.565 101.283 1.00 99.66  ? 60  THR A C   1 
ATOM   433  O O   . THR A 1 59  ? 147.955 132.818 101.070 1.00 105.95 ? 60  THR A O   1 
ATOM   434  C CB  . THR A 1 59  ? 149.181 135.182 99.390  1.00 99.13  ? 60  THR A CB  1 
ATOM   435  O OG1 . THR A 1 59  ? 150.488 134.654 99.136  1.00 106.36 ? 60  THR A OG1 1 
ATOM   436  C CG2 . THR A 1 59  ? 149.144 136.644 98.982  1.00 98.19  ? 60  THR A CG2 1 
ATOM   437  N N   . LEU A 1 60  ? 150.031 133.136 101.870 1.00 97.63  ? 61  LEU A N   1 
ATOM   438  C CA  . LEU A 1 60  ? 150.217 131.747 102.268 1.00 90.94  ? 61  LEU A CA  1 
ATOM   439  C C   . LEU A 1 60  ? 150.061 131.518 103.766 1.00 92.44  ? 61  LEU A C   1 
ATOM   440  O O   . LEU A 1 60  ? 150.199 130.375 104.211 1.00 96.23  ? 61  LEU A O   1 
ATOM   441  C CB  . LEU A 1 60  ? 151.596 131.253 101.820 1.00 102.21 ? 61  LEU A CB  1 
ATOM   442  C CG  . LEU A 1 60  ? 151.886 131.229 100.318 1.00 109.49 ? 61  LEU A CG  1 
ATOM   443  C CD1 . LEU A 1 60  ? 153.146 130.430 100.040 1.00 115.39 ? 61  LEU A CD1 1 
ATOM   444  C CD2 . LEU A 1 60  ? 150.713 130.658 99.538  1.00 106.56 ? 61  LEU A CD2 1 
ATOM   445  N N   . VAL A 1 61  ? 149.792 132.566 104.551 1.00 97.97  ? 62  VAL A N   1 
ATOM   446  C CA  . VAL A 1 61  ? 149.557 132.396 105.985 1.00 97.39  ? 62  VAL A CA  1 
ATOM   447  C C   . VAL A 1 61  ? 148.265 131.621 106.222 1.00 101.22 ? 62  VAL A C   1 
ATOM   448  O O   . VAL A 1 61  ? 148.184 130.773 107.120 1.00 107.19 ? 62  VAL A O   1 
ATOM   449  C CB  . VAL A 1 61  ? 149.555 133.772 106.684 1.00 99.65  ? 62  VAL A CB  1 
ATOM   450  C CG1 . VAL A 1 61  ? 149.120 133.672 108.141 1.00 100.45 ? 62  VAL A CG1 1 
ATOM   451  C CG2 . VAL A 1 61  ? 150.934 134.392 106.618 1.00 94.53  ? 62  VAL A CG2 1 
ATOM   452  N N   . THR A 1 62  ? 147.259 131.847 105.375 1.00 101.46 ? 63  THR A N   1 
ATOM   453  C CA  . THR A 1 62  ? 145.984 131.153 105.514 1.00 95.02  ? 63  THR A CA  1 
ATOM   454  C C   . THR A 1 62  ? 146.047 129.686 105.102 1.00 95.67  ? 63  THR A C   1 
ATOM   455  O O   . THR A 1 62  ? 145.070 128.960 105.307 1.00 101.87 ? 63  THR A O   1 
ATOM   456  C CB  . THR A 1 62  ? 144.907 131.857 104.699 1.00 100.94 ? 63  THR A CB  1 
ATOM   457  O OG1 . THR A 1 62  ? 143.631 131.293 105.027 1.00 107.22 ? 63  THR A OG1 1 
ATOM   458  C CG2 . THR A 1 62  ? 145.176 131.694 103.209 1.00 98.55  ? 63  THR A CG2 1 
ATOM   459  N N   . THR A 1 63  ? 147.147 129.237 104.505 1.00 100.51 ? 64  THR A N   1 
ATOM   460  C CA  . THR A 1 63  ? 147.337 127.817 104.254 1.00 96.81  ? 64  THR A CA  1 
ATOM   461  C C   . THR A 1 63  ? 148.271 127.166 105.262 1.00 100.08 ? 64  THR A C   1 
ATOM   462  O O   . THR A 1 63  ? 148.133 125.967 105.528 1.00 96.33  ? 64  THR A O   1 
ATOM   463  C CB  . THR A 1 63  ? 147.883 127.592 102.841 1.00 94.88  ? 64  THR A CB  1 
ATOM   464  O OG1 . THR A 1 63  ? 149.160 128.229 102.713 1.00 106.59 ? 64  THR A OG1 1 
ATOM   465  C CG2 . THR A 1 63  ? 146.933 128.171 101.808 1.00 87.36  ? 64  THR A CG2 1 
ATOM   466  N N   . LEU A 1 64  ? 149.198 127.928 105.842 1.00 100.97 ? 65  LEU A N   1 
ATOM   467  C CA  . LEU A 1 64  ? 150.177 127.383 106.776 1.00 103.60 ? 65  LEU A CA  1 
ATOM   468  C C   . LEU A 1 64  ? 149.690 127.484 108.220 1.00 106.05 ? 65  LEU A C   1 
ATOM   469  O O   . LEU A 1 64  ? 149.504 126.466 108.893 1.00 110.55 ? 65  LEU A O   1 
ATOM   470  C CB  . LEU A 1 64  ? 151.514 128.119 106.622 1.00 104.74 ? 65  LEU A CB  1 
ATOM   471  C CG  . LEU A 1 64  ? 152.276 128.029 105.299 1.00 102.24 ? 65  LEU A CG  1 
ATOM   472  C CD1 . LEU A 1 64  ? 153.203 129.224 105.157 1.00 99.89  ? 65  LEU A CD1 1 
ATOM   473  C CD2 . LEU A 1 64  ? 153.060 126.748 105.194 1.00 102.76 ? 65  LEU A CD2 1 
ATOM   474  N N   . GLY A 1 65  ? 149.474 128.706 108.701 1.00 112.58 ? 66  GLY A N   1 
ATOM   475  C CA  . GLY A 1 65  ? 149.080 128.926 110.079 1.00 120.43 ? 66  GLY A CA  1 
ATOM   476  C C   . GLY A 1 65  ? 147.619 128.631 110.336 1.00 118.54 ? 66  GLY A C   1 
ATOM   477  O O   . GLY A 1 65  ? 147.249 128.138 111.406 1.00 119.60 ? 66  GLY A O   1 
ATOM   478  N N   . TYR A 1 66  ? 146.774 128.929 109.349 1.00 114.82 ? 67  TYR A N   1 
ATOM   479  C CA  . TYR A 1 66  ? 145.354 128.619 109.446 1.00 107.10 ? 67  TYR A CA  1 
ATOM   480  C C   . TYR A 1 66  ? 145.065 127.155 109.159 1.00 107.77 ? 67  TYR A C   1 
ATOM   481  O O   . TYR A 1 66  ? 143.921 126.723 109.326 1.00 117.54 ? 67  TYR A O   1 
ATOM   482  C CB  . TYR A 1 66  ? 144.553 129.497 108.483 1.00 114.29 ? 67  TYR A CB  1 
ATOM   483  C CG  . TYR A 1 66  ? 144.214 130.900 108.962 1.00 110.00 ? 67  TYR A CG  1 
ATOM   484  C CD1 . TYR A 1 66  ? 145.113 131.652 109.712 1.00 109.92 ? 67  TYR A CD1 1 
ATOM   485  C CD2 . TYR A 1 66  ? 143.013 131.498 108.594 1.00 103.06 ? 67  TYR A CD2 1 
ATOM   486  C CE1 . TYR A 1 66  ? 144.804 132.932 110.125 1.00 111.28 ? 67  TYR A CE1 1 
ATOM   487  C CE2 . TYR A 1 66  ? 142.702 132.782 108.990 1.00 103.11 ? 67  TYR A CE2 1 
ATOM   488  C CZ  . TYR A 1 66  ? 143.598 133.491 109.761 1.00 107.26 ? 67  TYR A CZ  1 
ATOM   489  O OH  . TYR A 1 66  ? 143.287 134.768 110.165 1.00 110.40 ? 67  TYR A OH  1 
ATOM   490  N N   . GLY A 1 67  ? 146.059 126.391 108.712 1.00 111.85 ? 68  GLY A N   1 
ATOM   491  C CA  . GLY A 1 67  ? 145.905 124.957 108.593 1.00 120.53 ? 68  GLY A CA  1 
ATOM   492  C C   . GLY A 1 67  ? 146.077 124.201 109.888 1.00 121.87 ? 68  GLY A C   1 
ATOM   493  O O   . GLY A 1 67  ? 145.837 122.991 109.927 1.00 124.54 ? 68  GLY A O   1 
ATOM   494  N N   . LEU A 1 68  ? 146.491 124.890 110.948 1.00 115.42 ? 69  LEU A N   1 
ATOM   495  C CA  . LEU A 1 68  ? 146.637 124.282 112.264 1.00 112.22 ? 69  LEU A CA  1 
ATOM   496  C C   . LEU A 1 68  ? 145.408 124.611 113.110 1.00 116.47 ? 69  LEU A C   1 
ATOM   497  O O   . LEU A 1 68  ? 145.431 125.432 114.027 1.00 118.73 ? 69  LEU A O   1 
ATOM   498  C CB  . LEU A 1 68  ? 147.927 124.758 112.918 1.00 114.65 ? 69  LEU A CB  1 
ATOM   499  C CG  . LEU A 1 68  ? 149.175 124.274 112.182 1.00 119.34 ? 69  LEU A CG  1 
ATOM   500  C CD1 . LEU A 1 68  ? 150.424 124.896 112.768 1.00 122.71 ? 69  LEU A CD1 1 
ATOM   501  C CD2 . LEU A 1 68  ? 149.253 122.758 112.231 1.00 118.10 ? 69  LEU A CD2 1 
ATOM   502  N N   . GLN A 1 69  ? 144.316 123.936 112.766 1.00 112.07 ? 70  GLN A N   1 
ATOM   503  C CA  . GLN A 1 69  ? 143.035 124.088 113.441 1.00 110.19 ? 70  GLN A CA  1 
ATOM   504  C C   . GLN A 1 69  ? 142.985 123.409 114.802 1.00 112.14 ? 70  GLN A C   1 
ATOM   505  O O   . GLN A 1 69  ? 142.107 123.737 115.606 1.00 114.85 ? 70  GLN A O   1 
ATOM   506  C CB  . GLN A 1 69  ? 141.924 123.526 112.553 1.00 114.77 ? 70  GLN A CB  1 
ATOM   507  C CG  . GLN A 1 69  ? 141.683 124.295 111.272 1.00 111.08 ? 70  GLN A CG  1 
ATOM   508  C CD  . GLN A 1 69  ? 141.176 125.692 111.537 1.00 115.07 ? 70  GLN A CD  1 
ATOM   509  O OE1 . GLN A 1 69  ? 141.889 126.674 111.349 1.00 116.50 ? 70  GLN A OE1 1 
ATOM   510  N NE2 . GLN A 1 69  ? 139.929 125.792 111.982 1.00 117.55 ? 70  GLN A NE2 1 
ATOM   511  N N   . CYS A 1 70  ? 143.903 122.484 115.084 1.00 110.77 ? 71  CYS A N   1 
ATOM   512  C CA  . CYS A 1 70  ? 143.803 121.653 116.276 1.00 113.93 ? 71  CYS A CA  1 
ATOM   513  C C   . CYS A 1 70  ? 144.309 122.336 117.536 1.00 115.21 ? 71  CYS A C   1 
ATOM   514  O O   . CYS A 1 70  ? 144.140 121.779 118.624 1.00 121.77 ? 71  CYS A O   1 
ATOM   515  C CB  . CYS A 1 70  ? 144.579 120.360 116.074 1.00 121.30 ? 71  CYS A CB  1 
ATOM   516  S SG  . CYS A 1 70  ? 146.345 120.625 115.891 1.00 127.29 ? 71  CYS A SG  1 
ATOM   517  N N   . PHE A 1 71  ? 144.931 123.508 117.426 1.00 116.07 ? 72  PHE A N   1 
ATOM   518  C CA  . PHE A 1 71  ? 145.410 124.238 118.590 1.00 112.33 ? 72  PHE A CA  1 
ATOM   519  C C   . PHE A 1 71  ? 144.409 125.281 119.066 1.00 113.16 ? 72  PHE A C   1 
ATOM   520  O O   . PHE A 1 71  ? 144.807 126.316 119.608 1.00 119.41 ? 72  PHE A O   1 
ATOM   521  C CB  . PHE A 1 71  ? 146.760 124.889 118.289 1.00 113.97 ? 72  PHE A CB  1 
ATOM   522  C CG  . PHE A 1 71  ? 147.833 123.909 117.919 1.00 115.49 ? 72  PHE A CG  1 
ATOM   523  C CD1 . PHE A 1 71  ? 148.070 122.795 118.708 1.00 117.49 ? 72  PHE A CD1 1 
ATOM   524  C CD2 . PHE A 1 71  ? 148.606 124.099 116.785 1.00 120.66 ? 72  PHE A CD2 1 
ATOM   525  C CE1 . PHE A 1 71  ? 149.057 121.888 118.372 1.00 111.84 ? 72  PHE A CE1 1 
ATOM   526  C CE2 . PHE A 1 71  ? 149.595 123.195 116.444 1.00 123.25 ? 72  PHE A CE2 1 
ATOM   527  C CZ  . PHE A 1 71  ? 149.819 122.088 117.240 1.00 114.85 ? 72  PHE A CZ  1 
ATOM   528  N N   . ALA A 1 72  ? 143.119 125.027 118.871 1.00 113.45 ? 73  ALA A N   1 
ATOM   529  C CA  . ALA A 1 72  ? 142.094 125.974 119.273 1.00 115.07 ? 73  ALA A CA  1 
ATOM   530  C C   . ALA A 1 72  ? 141.860 125.920 120.776 1.00 119.20 ? 73  ALA A C   1 
ATOM   531  O O   . ALA A 1 72  ? 141.956 124.865 121.408 1.00 122.48 ? 73  ALA A O   1 
ATOM   532  C CB  . ALA A 1 72  ? 140.788 125.693 118.532 1.00 115.59 ? 73  ALA A CB  1 
ATOM   533  N N   . ARG A 1 73  ? 141.542 127.078 121.347 1.00 117.78 ? 74  ARG A N   1 
ATOM   534  C CA  . ARG A 1 73  ? 141.257 127.202 122.773 1.00 122.43 ? 74  ARG A CA  1 
ATOM   535  C C   . ARG A 1 73  ? 139.743 127.172 122.939 1.00 116.79 ? 74  ARG A C   1 
ATOM   536  O O   . ARG A 1 73  ? 139.071 128.198 122.815 1.00 115.86 ? 74  ARG A O   1 
ATOM   537  C CB  . ARG A 1 73  ? 141.867 128.480 123.339 1.00 128.05 ? 74  ARG A CB  1 
ATOM   538  C CG  . ARG A 1 73  ? 141.609 128.712 124.821 1.00 126.70 ? 74  ARG A CG  1 
ATOM   539  C CD  . ARG A 1 73  ? 142.156 130.058 125.258 1.00 127.92 ? 74  ARG A CD  1 
ATOM   540  N NE  . ARG A 1 73  ? 141.639 130.463 126.558 1.00 142.43 ? 74  ARG A NE  1 
ATOM   541  C CZ  . ARG A 1 73  ? 141.872 131.641 127.121 1.00 148.56 ? 74  ARG A CZ  1 
ATOM   542  N NH1 . ARG A 1 73  ? 142.614 132.559 126.523 1.00 147.63 ? 74  ARG A NH1 1 
ATOM   543  N NH2 . ARG A 1 73  ? 141.347 131.905 128.315 1.00 149.14 ? 74  ARG A NH2 1 
ATOM   544  N N   . TYR A 1 74  ? 139.203 125.984 123.200 1.00 121.95 ? 75  TYR A N   1 
ATOM   545  C CA  . TYR A 1 74  ? 137.777 125.832 123.429 1.00 129.56 ? 75  TYR A CA  1 
ATOM   546  C C   . TYR A 1 74  ? 137.490 125.999 124.909 1.00 141.55 ? 75  TYR A C   1 
ATOM   547  O O   . TYR A 1 74  ? 138.255 125.480 125.739 1.00 144.86 ? 75  TYR A O   1 
ATOM   548  C CB  . TYR A 1 74  ? 137.292 124.470 122.950 1.00 133.92 ? 75  TYR A CB  1 
ATOM   549  C CG  . TYR A 1 74  ? 136.976 124.413 121.476 1.00 128.65 ? 75  TYR A CG  1 
ATOM   550  C CD1 . TYR A 1 74  ? 135.707 124.725 121.009 1.00 134.71 ? 75  TYR A CD1 1 
ATOM   551  C CD2 . TYR A 1 74  ? 137.940 124.031 120.553 1.00 125.14 ? 75  TYR A CD2 1 
ATOM   552  C CE1 . TYR A 1 74  ? 135.409 124.674 119.662 1.00 131.43 ? 75  TYR A CE1 1 
ATOM   553  C CE2 . TYR A 1 74  ? 137.650 123.974 119.203 1.00 125.84 ? 75  TYR A CE2 1 
ATOM   554  C CZ  . TYR A 1 74  ? 136.383 124.295 118.765 1.00 127.77 ? 75  TYR A CZ  1 
ATOM   555  O OH  . TYR A 1 74  ? 136.090 124.239 117.422 1.00 129.14 ? 75  TYR A OH  1 
ATOM   556  N N   . PRO A 1 75  ? 136.423 126.701 125.292 1.00 140.16 ? 76  PRO A N   1 
ATOM   557  C CA  . PRO A 1 75  ? 136.095 126.826 126.719 1.00 142.55 ? 76  PRO A CA  1 
ATOM   558  C C   . PRO A 1 75  ? 135.469 125.564 127.292 1.00 144.57 ? 76  PRO A C   1 
ATOM   559  O O   . PRO A 1 75  ? 135.403 124.527 126.623 1.00 147.00 ? 76  PRO A O   1 
ATOM   560  C CB  . PRO A 1 75  ? 135.113 128.002 126.756 1.00 141.42 ? 76  PRO A CB  1 
ATOM   561  C CG  . PRO A 1 75  ? 134.540 128.061 125.399 1.00 136.84 ? 76  PRO A CG  1 
ATOM   562  C CD  . PRO A 1 75  ? 135.564 127.541 124.443 1.00 131.40 ? 76  PRO A CD  1 
ATOM   563  N N   . ASP A 1 76  ? 135.012 125.650 128.544 1.00 149.96 ? 77  ASP A N   1 
ATOM   564  C CA  . ASP A 1 76  ? 134.415 124.493 129.207 1.00 160.53 ? 77  ASP A CA  1 
ATOM   565  C C   . ASP A 1 76  ? 133.076 124.115 128.582 1.00 156.61 ? 77  ASP A C   1 
ATOM   566  O O   . ASP A 1 76  ? 132.659 122.952 128.647 1.00 156.80 ? 77  ASP A O   1 
ATOM   567  C CB  . ASP A 1 76  ? 134.244 124.782 130.698 1.00 162.35 ? 77  ASP A CB  1 
ATOM   568  C CG  . ASP A 1 76  ? 135.566 125.014 131.403 1.00 165.15 ? 77  ASP A CG  1 
ATOM   569  O OD1 . ASP A 1 76  ? 136.624 124.831 130.764 1.00 165.68 ? 77  ASP A OD1 1 
ATOM   570  O OD2 . ASP A 1 76  ? 135.548 125.385 132.595 1.00 164.84 ? 77  ASP A OD2 1 
ATOM   571  N N   . HIS A 1 77  ? 132.387 125.083 127.973 1.00 146.93 ? 78  HIS A N   1 
ATOM   572  C CA  . HIS A 1 77  ? 131.059 124.820 127.427 1.00 143.06 ? 78  HIS A CA  1 
ATOM   573  C C   . HIS A 1 77  ? 131.134 124.018 126.130 1.00 145.07 ? 78  HIS A C   1 
ATOM   574  O O   . HIS A 1 77  ? 130.346 123.089 125.920 1.00 140.66 ? 78  HIS A O   1 
ATOM   575  C CB  . HIS A 1 77  ? 130.318 126.139 127.208 1.00 142.60 ? 78  HIS A CB  1 
ATOM   576  C CG  . HIS A 1 77  ? 128.879 125.967 126.837 1.00 152.01 ? 78  HIS A CG  1 
ATOM   577  N ND1 . HIS A 1 77  ? 128.461 125.789 125.536 1.00 154.69 ? 78  HIS A ND1 1 
ATOM   578  C CD2 . HIS A 1 77  ? 127.759 125.947 127.598 1.00 154.49 ? 78  HIS A CD2 1 
ATOM   579  C CE1 . HIS A 1 77  ? 127.146 125.663 125.512 1.00 153.93 ? 78  HIS A CE1 1 
ATOM   580  N NE2 . HIS A 1 77  ? 126.696 125.757 126.750 1.00 154.11 ? 78  HIS A NE2 1 
ATOM   581  N N   . MET A 1 78  ? 132.077 124.356 125.251 1.00 148.13 ? 79  MET A N   1 
ATOM   582  C CA  . MET A 1 78  ? 132.184 123.729 123.932 1.00 143.82 ? 79  MET A CA  1 
ATOM   583  C C   . MET A 1 78  ? 133.314 122.711 123.847 1.00 140.77 ? 79  MET A C   1 
ATOM   584  O O   . MET A 1 78  ? 134.006 122.635 122.829 1.00 141.43 ? 79  MET A O   1 
ATOM   585  C CB  . MET A 1 78  ? 132.340 124.780 122.835 1.00 139.32 ? 79  MET A CB  1 
ATOM   586  C CG  . MET A 1 78  ? 131.044 125.470 122.442 1.00 145.83 ? 79  MET A CG  1 
ATOM   587  S SD  . MET A 1 78  ? 130.452 126.700 123.609 1.00 162.51 ? 79  MET A SD  1 
ATOM   588  C CE  . MET A 1 78  ? 131.561 128.054 123.245 1.00 139.32 ? 79  MET A CE  1 
ATOM   589  N N   . LYS A 1 79  ? 133.534 121.918 124.899 1.00 139.30 ? 80  LYS A N   1 
ATOM   590  C CA  . LYS A 1 79  ? 134.403 120.754 124.757 1.00 142.54 ? 80  LYS A CA  1 
ATOM   591  C C   . LYS A 1 79  ? 133.760 119.678 123.890 1.00 140.27 ? 80  LYS A C   1 
ATOM   592  O O   . LYS A 1 79  ? 134.467 118.873 123.274 1.00 137.52 ? 80  LYS A O   1 
ATOM   593  C CB  . LYS A 1 79  ? 134.761 120.185 126.130 1.00 142.44 ? 80  LYS A CB  1 
ATOM   594  C CG  . LYS A 1 79  ? 135.539 121.135 127.021 1.00 142.70 ? 80  LYS A CG  1 
ATOM   595  C CD  . LYS A 1 79  ? 136.925 121.389 126.453 1.00 144.58 ? 80  LYS A CD  1 
ATOM   596  C CE  . LYS A 1 79  ? 137.748 122.274 127.371 1.00 149.64 ? 80  LYS A CE  1 
ATOM   597  N NZ  . LYS A 1 79  ? 139.091 122.562 126.798 1.00 144.23 ? 80  LYS A NZ  1 
ATOM   598  N N   . GLN A 1 80  ? 132.428 119.648 123.829 1.00 140.50 ? 81  GLN A N   1 
ATOM   599  C CA  . GLN A 1 80  ? 131.734 118.663 123.008 1.00 139.20 ? 81  GLN A CA  1 
ATOM   600  C C   . GLN A 1 80  ? 131.643 119.082 121.545 1.00 137.21 ? 81  GLN A C   1 
ATOM   601  O O   . GLN A 1 80  ? 131.521 118.220 120.669 1.00 140.41 ? 81  GLN A O   1 
ATOM   602  C CB  . GLN A 1 80  ? 130.338 118.402 123.583 1.00 142.16 ? 81  GLN A CB  1 
ATOM   603  C CG  . GLN A 1 80  ? 129.409 119.608 123.566 1.00 135.77 ? 81  GLN A CG  1 
ATOM   604  C CD  . GLN A 1 80  ? 128.070 119.323 124.209 1.00 127.53 ? 81  GLN A CD  1 
ATOM   605  O OE1 . GLN A 1 80  ? 127.797 118.201 124.633 1.00 117.29 ? 81  GLN A OE1 1 
ATOM   606  N NE2 . GLN A 1 80  ? 127.225 120.342 124.288 1.00 133.56 ? 81  GLN A NE2 1 
ATOM   607  N N   . HIS A 1 81  ? 131.694 120.379 121.258 1.00 134.34 ? 82  HIS A N   1 
ATOM   608  C CA  . HIS A 1 81  ? 131.655 120.875 119.882 1.00 134.13 ? 82  HIS A CA  1 
ATOM   609  C C   . HIS A 1 81  ? 133.067 121.142 119.362 1.00 133.41 ? 82  HIS A C   1 
ATOM   610  O O   . HIS A 1 81  ? 133.422 122.259 118.994 1.00 129.67 ? 82  HIS A O   1 
ATOM   611  C CB  . HIS A 1 81  ? 130.790 122.128 119.797 1.00 133.46 ? 82  HIS A CB  1 
ATOM   612  C CG  . HIS A 1 81  ? 129.379 121.924 120.252 1.00 139.89 ? 82  HIS A CG  1 
ATOM   613  N ND1 . HIS A 1 81  ? 128.673 120.769 119.991 1.00 142.64 ? 82  HIS A ND1 1 
ATOM   614  C CD2 . HIS A 1 81  ? 128.538 122.731 120.940 1.00 139.61 ? 82  HIS A CD2 1 
ATOM   615  C CE1 . HIS A 1 81  ? 127.460 120.872 120.504 1.00 143.25 ? 82  HIS A CE1 1 
ATOM   616  N NE2 . HIS A 1 81  ? 127.352 122.053 121.085 1.00 141.62 ? 82  HIS A NE2 1 
ATOM   617  N N   . ASP A 1 82  ? 133.876 120.085 119.318 1.00 133.40 ? 83  ASP A N   1 
ATOM   618  C CA  . ASP A 1 82  ? 135.277 120.198 118.921 1.00 126.10 ? 83  ASP A CA  1 
ATOM   619  C C   . ASP A 1 82  ? 135.585 119.044 117.976 1.00 125.43 ? 83  ASP A C   1 
ATOM   620  O O   . ASP A 1 82  ? 135.779 117.909 118.421 1.00 128.13 ? 83  ASP A O   1 
ATOM   621  C CB  . ASP A 1 82  ? 136.191 120.178 120.147 1.00 127.66 ? 83  ASP A CB  1 
ATOM   622  C CG  . ASP A 1 82  ? 137.632 120.548 119.829 1.00 133.03 ? 83  ASP A CG  1 
ATOM   623  O OD1 . ASP A 1 82  ? 137.970 120.811 118.655 1.00 128.33 ? 83  ASP A OD1 1 
ATOM   624  O OD2 . ASP A 1 82  ? 138.437 120.586 120.779 1.00 140.35 ? 83  ASP A OD2 1 
ATOM   625  N N   . PHE A 1 83  ? 135.642 119.338 116.678 1.00 121.74 ? 84  PHE A N   1 
ATOM   626  C CA  . PHE A 1 83  ? 135.860 118.322 115.658 1.00 116.47 ? 84  PHE A CA  1 
ATOM   627  C C   . PHE A 1 83  ? 137.336 118.039 115.410 1.00 116.91 ? 84  PHE A C   1 
ATOM   628  O O   . PHE A 1 83  ? 137.678 116.914 115.022 1.00 118.32 ? 84  PHE A O   1 
ATOM   629  C CB  . PHE A 1 83  ? 135.157 118.753 114.356 1.00 121.57 ? 84  PHE A CB  1 
ATOM   630  C CG  . PHE A 1 83  ? 135.583 117.988 113.125 1.00 119.48 ? 84  PHE A CG  1 
ATOM   631  C CD1 . PHE A 1 83  ? 135.035 116.746 112.846 1.00 118.86 ? 84  PHE A CD1 1 
ATOM   632  C CD2 . PHE A 1 83  ? 136.485 118.536 112.219 1.00 120.08 ? 84  PHE A CD2 1 
ATOM   633  C CE1 . PHE A 1 83  ? 135.411 116.044 111.716 1.00 120.76 ? 84  PHE A CE1 1 
ATOM   634  C CE2 . PHE A 1 83  ? 136.865 117.840 111.088 1.00 121.08 ? 84  PHE A CE2 1 
ATOM   635  C CZ  . PHE A 1 83  ? 136.325 116.594 110.835 1.00 121.79 ? 84  PHE A CZ  1 
ATOM   636  N N   . PHE A 1 84  ? 138.209 119.022 115.648 1.00 121.39 ? 85  PHE A N   1 
ATOM   637  C CA  . PHE A 1 84  ? 139.609 118.904 115.250 1.00 114.26 ? 85  PHE A CA  1 
ATOM   638  C C   . PHE A 1 84  ? 140.350 117.861 116.077 1.00 117.56 ? 85  PHE A C   1 
ATOM   639  O O   . PHE A 1 84  ? 141.012 116.979 115.519 1.00 117.48 ? 85  PHE A O   1 
ATOM   640  C CB  . PHE A 1 84  ? 140.290 120.265 115.364 1.00 113.40 ? 85  PHE A CB  1 
ATOM   641  C CG  . PHE A 1 84  ? 139.528 121.373 114.702 1.00 116.51 ? 85  PHE A CG  1 
ATOM   642  C CD1 . PHE A 1 84  ? 139.219 121.306 113.355 1.00 109.49 ? 85  PHE A CD1 1 
ATOM   643  C CD2 . PHE A 1 84  ? 139.110 122.475 115.429 1.00 117.54 ? 85  PHE A CD2 1 
ATOM   644  C CE1 . PHE A 1 84  ? 138.517 122.323 112.741 1.00 107.98 ? 85  PHE A CE1 1 
ATOM   645  C CE2 . PHE A 1 84  ? 138.404 123.496 114.821 1.00 109.67 ? 85  PHE A CE2 1 
ATOM   646  C CZ  . PHE A 1 84  ? 138.107 123.418 113.475 1.00 107.75 ? 85  PHE A CZ  1 
ATOM   647  N N   . LYS A 1 85  ? 140.224 117.917 117.399 1.00 122.88 ? 86  LYS A N   1 
ATOM   648  C CA  . LYS A 1 85  ? 140.861 116.931 118.262 1.00 123.66 ? 86  LYS A CA  1 
ATOM   649  C C   . LYS A 1 85  ? 139.992 115.709 118.506 1.00 124.27 ? 86  LYS A C   1 
ATOM   650  O O   . LYS A 1 85  ? 140.345 114.882 119.353 1.00 133.96 ? 86  LYS A O   1 
ATOM   651  C CB  . LYS A 1 85  ? 141.235 117.544 119.615 1.00 125.01 ? 86  LYS A CB  1 
ATOM   652  C CG  . LYS A 1 85  ? 141.642 118.998 119.588 1.00 118.77 ? 86  LYS A CG  1 
ATOM   653  C CD  . LYS A 1 85  ? 141.561 119.576 120.988 1.00 116.20 ? 86  LYS A CD  1 
ATOM   654  C CE  . LYS A 1 85  ? 141.896 121.048 121.004 1.00 120.85 ? 86  LYS A CE  1 
ATOM   655  N NZ  . LYS A 1 85  ? 143.348 121.252 120.811 1.00 128.06 ? 86  LYS A NZ  1 
ATOM   656  N N   . SER A 1 86  ? 138.860 115.588 117.808 1.00 121.60 ? 87  SER A N   1 
ATOM   657  C CA  . SER A 1 86  ? 137.932 114.495 118.080 1.00 124.14 ? 87  SER A CA  1 
ATOM   658  C C   . SER A 1 86  ? 138.504 113.160 117.618 1.00 125.39 ? 87  SER A C   1 
ATOM   659  O O   . SER A 1 86  ? 138.395 112.149 118.322 1.00 134.26 ? 87  SER A O   1 
ATOM   660  C CB  . SER A 1 86  ? 136.586 114.775 117.415 1.00 127.56 ? 87  SER A CB  1 
ATOM   661  O OG  . SER A 1 86  ? 135.676 113.724 117.672 1.00 126.34 ? 87  SER A OG  1 
ATOM   662  N N   . ALA A 1 87  ? 139.119 113.134 116.432 1.00 114.28 ? 88  ALA A N   1 
ATOM   663  C CA  . ALA A 1 87  ? 140.010 112.041 116.032 1.00 117.91 ? 88  ALA A CA  1 
ATOM   664  C C   . ALA A 1 87  ? 141.284 112.698 115.511 1.00 122.75 ? 88  ALA A C   1 
ATOM   665  O O   . ALA A 1 87  ? 141.486 112.830 114.303 1.00 125.48 ? 88  ALA A O   1 
ATOM   666  C CB  . ALA A 1 87  ? 139.359 111.137 114.990 1.00 111.09 ? 88  ALA A CB  1 
ATOM   667  N N   . MET A 1 88  ? 142.143 113.110 116.436 1.00 122.73 ? 89  MET A N   1 
ATOM   668  C CA  . MET A 1 88  ? 143.377 113.804 116.085 1.00 122.97 ? 89  MET A CA  1 
ATOM   669  C C   . MET A 1 88  ? 144.566 112.893 115.738 1.00 128.02 ? 89  MET A C   1 
ATOM   670  O O   . MET A 1 88  ? 145.239 113.183 114.739 1.00 127.10 ? 89  MET A O   1 
ATOM   671  C CB  . MET A 1 88  ? 143.766 114.797 117.186 1.00 123.66 ? 89  MET A CB  1 
ATOM   672  C CG  . MET A 1 88  ? 144.882 115.709 116.747 1.00 132.85 ? 89  MET A CG  1 
ATOM   673  S SD  . MET A 1 88  ? 144.217 116.745 115.433 1.00 152.15 ? 89  MET A SD  1 
ATOM   674  C CE  . MET A 1 88  ? 145.685 117.196 114.536 1.00 134.59 ? 89  MET A CE  1 
ATOM   675  N N   . PRO A 1 89  ? 144.911 111.787 116.535 1.00 126.13 ? 90  PRO A N   1 
ATOM   676  C CA  . PRO A 1 89  ? 146.104 110.989 116.184 1.00 130.11 ? 90  PRO A CA  1 
ATOM   677  C C   . PRO A 1 89  ? 146.072 110.319 114.817 1.00 130.65 ? 90  PRO A C   1 
ATOM   678  O O   . PRO A 1 89  ? 147.125 110.010 114.251 1.00 130.11 ? 90  PRO A O   1 
ATOM   679  C CB  . PRO A 1 89  ? 146.161 109.925 117.291 1.00 127.26 ? 90  PRO A CB  1 
ATOM   680  C CG  . PRO A 1 89  ? 144.847 109.957 117.943 1.00 127.49 ? 90  PRO A CG  1 
ATOM   681  C CD  . PRO A 1 89  ? 144.420 111.364 117.864 1.00 120.25 ? 90  PRO A CD  1 
ATOM   682  N N   . GLU A 1 90  ? 144.875 110.081 114.283 1.00 124.07 ? 91  GLU A N   1 
ATOM   683  C CA  . GLU A 1 90  ? 144.772 109.571 112.922 1.00 123.58 ? 91  GLU A CA  1 
ATOM   684  C C   . GLU A 1 90  ? 145.140 110.641 111.898 1.00 121.45 ? 91  GLU A C   1 
ATOM   685  O O   . GLU A 1 90  ? 145.778 110.341 110.883 1.00 118.67 ? 91  GLU A O   1 
ATOM   686  C CB  . GLU A 1 90  ? 143.363 109.038 112.674 1.00 128.28 ? 91  GLU A CB  1 
ATOM   687  C CG  . GLU A 1 90  ? 143.023 107.807 113.499 1.00 128.23 ? 91  GLU A CG  1 
ATOM   688  C CD  . GLU A 1 90  ? 143.829 106.588 113.095 1.00 129.56 ? 91  GLU A CD  1 
ATOM   689  O OE1 . GLU A 1 90  ? 144.162 106.460 111.898 1.00 128.07 ? 91  GLU A OE1 1 
ATOM   690  O OE2 . GLU A 1 90  ? 144.131 105.757 113.976 1.00 132.00 ? 91  GLU A OE2 1 
ATOM   691  N N   . GLY A 1 91  ? 144.762 111.890 112.151 1.00 121.41 ? 92  GLY A N   1 
ATOM   692  C CA  . GLY A 1 91  ? 145.003 112.980 111.224 1.00 125.83 ? 92  GLY A CA  1 
ATOM   693  C C   . GLY A 1 91  ? 143.772 113.286 110.392 1.00 122.38 ? 92  GLY A C   1 
ATOM   694  O O   . GLY A 1 91  ? 142.759 112.581 110.434 1.00 125.25 ? 92  GLY A O   1 
ATOM   695  N N   . TYR A 1 92  ? 143.868 114.363 109.613 1.00 114.04 ? 93  TYR A N   1 
ATOM   696  C CA  . TYR A 1 92  ? 142.733 114.767 108.790 1.00 110.90 ? 93  TYR A CA  1 
ATOM   697  C C   . TYR A 1 92  ? 143.200 115.562 107.577 1.00 109.95 ? 93  TYR A C   1 
ATOM   698  O O   . TYR A 1 92  ? 144.342 116.025 107.505 1.00 114.66 ? 93  TYR A O   1 
ATOM   699  C CB  . TYR A 1 92  ? 141.691 115.552 109.607 1.00 114.73 ? 93  TYR A CB  1 
ATOM   700  C CG  . TYR A 1 92  ? 142.152 116.857 110.222 1.00 108.16 ? 93  TYR A CG  1 
ATOM   701  C CD1 . TYR A 1 92  ? 142.710 116.884 111.494 1.00 103.82 ? 93  TYR A CD1 1 
ATOM   702  C CD2 . TYR A 1 92  ? 141.980 118.066 109.557 1.00 109.14 ? 93  TYR A CD2 1 
ATOM   703  C CE1 . TYR A 1 92  ? 143.114 118.072 112.072 1.00 102.76 ? 93  TYR A CE1 1 
ATOM   704  C CE2 . TYR A 1 92  ? 142.383 119.260 110.128 1.00 103.76 ? 93  TYR A CE2 1 
ATOM   705  C CZ  . TYR A 1 92  ? 142.948 119.255 111.385 1.00 100.15 ? 93  TYR A CZ  1 
ATOM   706  O OH  . TYR A 1 92  ? 143.349 120.437 111.957 1.00 109.62 ? 93  TYR A OH  1 
ATOM   707  N N   . VAL A 1 93  ? 142.288 115.708 106.618 1.00 98.91  ? 94  VAL A N   1 
ATOM   708  C CA  . VAL A 1 93  ? 142.571 116.296 105.316 1.00 100.68 ? 94  VAL A CA  1 
ATOM   709  C C   . VAL A 1 93  ? 141.857 117.634 105.216 1.00 104.05 ? 94  VAL A C   1 
ATOM   710  O O   . VAL A 1 93  ? 140.648 117.724 105.471 1.00 113.26 ? 94  VAL A O   1 
ATOM   711  C CB  . VAL A 1 93  ? 142.120 115.369 104.169 1.00 107.90 ? 94  VAL A CB  1 
ATOM   712  C CG1 . VAL A 1 93  ? 142.457 115.975 102.815 1.00 107.42 ? 94  VAL A CG1 1 
ATOM   713  C CG2 . VAL A 1 93  ? 142.725 113.999 104.314 1.00 114.03 ? 94  VAL A CG2 1 
ATOM   714  N N   . GLN A 1 94  ? 142.607 118.669 104.841 1.00 100.16 ? 95  GLN A N   1 
ATOM   715  C CA  . GLN A 1 94  ? 142.054 119.972 104.498 1.00 101.82 ? 95  GLN A CA  1 
ATOM   716  C C   . GLN A 1 94  ? 142.110 120.126 102.987 1.00 100.27 ? 95  GLN A C   1 
ATOM   717  O O   . GLN A 1 94  ? 143.198 120.129 102.404 1.00 100.49 ? 95  GLN A O   1 
ATOM   718  C CB  . GLN A 1 94  ? 142.838 121.111 105.154 1.00 99.24  ? 95  GLN A CB  1 
ATOM   719  C CG  . GLN A 1 94  ? 142.768 121.170 106.660 1.00 102.61 ? 95  GLN A CG  1 
ATOM   720  C CD  . GLN A 1 94  ? 143.547 122.334 107.220 1.00 113.69 ? 95  GLN A CD  1 
ATOM   721  O OE1 . GLN A 1 94  ? 144.203 123.065 106.480 1.00 118.93 ? 95  GLN A OE1 1 
ATOM   722  N NE2 . GLN A 1 94  ? 143.466 122.528 108.531 1.00 114.67 ? 95  GLN A NE2 1 
ATOM   723  N N   . GLU A 1 95  ? 140.956 120.271 102.349 1.00 104.69 ? 96  GLU A N   1 
ATOM   724  C CA  . GLU A 1 95  ? 140.920 120.593 100.929 1.00 104.25 ? 96  GLU A CA  1 
ATOM   725  C C   . GLU A 1 95  ? 140.298 121.978 100.811 1.00 104.44 ? 96  GLU A C   1 
ATOM   726  O O   . GLU A 1 95  ? 139.155 122.192 101.227 1.00 108.67 ? 96  GLU A O   1 
ATOM   727  C CB  . GLU A 1 95  ? 140.160 119.534 100.132 1.00 104.91 ? 96  GLU A CB  1 
ATOM   728  C CG  . GLU A 1 95  ? 140.094 119.800 98.633  1.00 104.88 ? 96  GLU A CG  1 
ATOM   729  C CD  . GLU A 1 95  ? 138.807 120.458 98.203  1.00 112.73 ? 96  GLU A CD  1 
ATOM   730  O OE1 . GLU A 1 95  ? 137.798 120.286 98.911  1.00 116.68 ? 96  GLU A OE1 1 
ATOM   731  O OE2 . GLU A 1 95  ? 138.802 121.147 97.162  1.00 119.07 ? 96  GLU A OE2 1 
ATOM   732  N N   . ARG A 1 96  ? 141.063 122.918 100.269 1.00 101.07 ? 97  ARG A N   1 
ATOM   733  C CA  . ARG A 1 96  ? 140.714 124.329 100.281 1.00 96.52  ? 97  ARG A CA  1 
ATOM   734  C C   . ARG A 1 96  ? 140.688 124.866 98.861  1.00 101.66 ? 97  ARG A C   1 
ATOM   735  O O   . ARG A 1 96  ? 141.536 124.507 98.037  1.00 101.83 ? 97  ARG A O   1 
ATOM   736  C CB  . ARG A 1 96  ? 141.730 125.140 101.093 1.00 97.50  ? 97  ARG A CB  1 
ATOM   737  C CG  . ARG A 1 96  ? 141.498 125.208 102.583 1.00 86.11  ? 97  ARG A CG  1 
ATOM   738  C CD  . ARG A 1 96  ? 142.019 126.523 103.139 1.00 85.45  ? 97  ARG A CD  1 
ATOM   739  N NE  . ARG A 1 96  ? 141.513 126.814 104.474 1.00 89.84  ? 97  ARG A NE  1 
ATOM   740  C CZ  . ARG A 1 96  ? 142.268 126.880 105.562 1.00 86.91  ? 97  ARG A CZ  1 
ATOM   741  N NH1 . ARG A 1 96  ? 143.574 126.683 105.509 1.00 96.06  ? 97  ARG A NH1 1 
ATOM   742  N NH2 . ARG A 1 96  ? 141.697 127.145 106.732 1.00 81.27  ? 97  ARG A NH2 1 
ATOM   743  N N   . THR A 1 97  ? 139.727 125.738 98.576  1.00 102.48 ? 98  THR A N   1 
ATOM   744  C CA  . THR A 1 97  ? 139.820 126.604 97.409  1.00 97.59  ? 98  THR A CA  1 
ATOM   745  C C   . THR A 1 97  ? 139.867 128.047 97.897  1.00 100.33 ? 98  THR A C   1 
ATOM   746  O O   . THR A 1 97  ? 139.148 128.427 98.836  1.00 98.99  ? 98  THR A O   1 
ATOM   747  C CB  . THR A 1 97  ? 138.696 126.344 96.391  1.00 96.74  ? 98  THR A CB  1 
ATOM   748  O OG1 . THR A 1 97  ? 138.925 127.123 95.210  1.00 101.14 ? 98  THR A OG1 1 
ATOM   749  C CG2 . THR A 1 97  ? 137.307 126.624 96.935  1.00 102.27 ? 98  THR A CG2 1 
ATOM   750  N N   . ILE A 1 98  ? 140.781 128.820 97.317  1.00 104.59 ? 99  ILE A N   1 
ATOM   751  C CA  . ILE A 1 98  ? 141.125 130.153 97.790  1.00 103.66 ? 99  ILE A CA  1 
ATOM   752  C C   . ILE A 1 98  ? 140.938 131.092 96.607  1.00 113.95 ? 99  ILE A C   1 
ATOM   753  O O   . ILE A 1 98  ? 141.770 131.118 95.689  1.00 119.44 ? 99  ILE A O   1 
ATOM   754  C CB  . ILE A 1 98  ? 142.568 130.214 98.310  1.00 104.76 ? 99  ILE A CB  1 
ATOM   755  C CG1 . ILE A 1 98  ? 142.837 129.151 99.383  1.00 103.32 ? 99  ILE A CG1 1 
ATOM   756  C CG2 . ILE A 1 98  ? 142.918 131.611 98.795  1.00 103.84 ? 99  ILE A CG2 1 
ATOM   757  C CD1 . ILE A 1 98  ? 141.994 129.248 100.597 1.00 108.75 ? 99  ILE A CD1 1 
ATOM   758  N N   . PHE A 1 99  ? 139.849 131.852 96.617  1.00 107.56 ? 100 PHE A N   1 
ATOM   759  C CA  . PHE A 1 99  ? 139.484 132.732 95.519  1.00 107.76 ? 100 PHE A CA  1 
ATOM   760  C C   . PHE A 1 99  ? 139.965 134.142 95.830  1.00 98.95  ? 100 PHE A C   1 
ATOM   761  O O   . PHE A 1 99  ? 139.568 134.727 96.842  1.00 97.77  ? 100 PHE A O   1 
ATOM   762  C CB  . PHE A 1 99  ? 137.971 132.729 95.304  1.00 106.80 ? 100 PHE A CB  1 
ATOM   763  C CG  . PHE A 1 99  ? 137.434 131.433 94.776  1.00 101.45 ? 100 PHE A CG  1 
ATOM   764  C CD1 . PHE A 1 99  ? 137.908 130.902 93.590  1.00 104.66 ? 100 PHE A CD1 1 
ATOM   765  C CD2 . PHE A 1 99  ? 136.448 130.750 95.468  1.00 98.51  ? 100 PHE A CD2 1 
ATOM   766  C CE1 . PHE A 1 99  ? 137.410 129.710 93.102  1.00 106.28 ? 100 PHE A CE1 1 
ATOM   767  C CE2 . PHE A 1 99  ? 135.946 129.558 94.986  1.00 110.16 ? 100 PHE A CE2 1 
ATOM   768  C CZ  . PHE A 1 99  ? 136.429 129.037 93.802  1.00 109.58 ? 100 PHE A CZ  1 
ATOM   769  N N   . PHE A 1 100 ? 140.807 134.683 94.960  1.00 100.50 ? 101 PHE A N   1 
ATOM   770  C CA  . PHE A 1 100 ? 141.250 136.066 95.056  1.00 104.68 ? 101 PHE A CA  1 
ATOM   771  C C   . PHE A 1 100 ? 140.367 136.919 94.158  1.00 106.49 ? 101 PHE A C   1 
ATOM   772  O O   . PHE A 1 100 ? 140.027 136.503 93.045  1.00 107.67 ? 101 PHE A O   1 
ATOM   773  C CB  . PHE A 1 100 ? 142.717 136.207 94.643  1.00 111.41 ? 101 PHE A CB  1 
ATOM   774  C CG  . PHE A 1 100 ? 143.706 135.741 95.682  1.00 109.57 ? 101 PHE A CG  1 
ATOM   775  C CD1 . PHE A 1 100 ? 143.293 135.339 96.943  1.00 108.58 ? 101 PHE A CD1 1 
ATOM   776  C CD2 . PHE A 1 100 ? 145.060 135.703 95.385  1.00 111.15 ? 101 PHE A CD2 1 
ATOM   777  C CE1 . PHE A 1 100 ? 144.209 134.912 97.886  1.00 108.22 ? 101 PHE A CE1 1 
ATOM   778  C CE2 . PHE A 1 100 ? 145.980 135.276 96.323  1.00 109.95 ? 101 PHE A CE2 1 
ATOM   779  C CZ  . PHE A 1 100 ? 145.553 134.882 97.575  1.00 106.03 ? 101 PHE A CZ  1 
ATOM   780  N N   . LYS A 1 101 ? 139.977 138.093 94.651  1.00 103.62 ? 102 LYS A N   1 
ATOM   781  C CA  . LYS A 1 101 ? 139.216 139.029 93.834  1.00 101.71 ? 102 LYS A CA  1 
ATOM   782  C C   . LYS A 1 101 ? 140.105 139.556 92.714  1.00 113.44 ? 102 LYS A C   1 
ATOM   783  O O   . LYS A 1 101 ? 141.285 139.832 92.944  1.00 120.36 ? 102 LYS A O   1 
ATOM   784  C CB  . LYS A 1 101 ? 138.681 140.169 94.700  1.00 106.81 ? 102 LYS A CB  1 
ATOM   785  C CG  . LYS A 1 101 ? 138.049 141.315 93.933  1.00 110.41 ? 102 LYS A CG  1 
ATOM   786  C CD  . LYS A 1 101 ? 137.592 142.413 94.875  1.00 115.44 ? 102 LYS A CD  1 
ATOM   787  C CE  . LYS A 1 101 ? 136.492 143.253 94.250  1.00 132.01 ? 102 LYS A CE  1 
ATOM   788  N NZ  . LYS A 1 101 ? 136.528 144.661 94.733  1.00 134.42 ? 102 LYS A NZ  1 
ATOM   789  N N   . ASP A 1 102 ? 139.542 139.558 91.490  1.00 112.80 ? 103 ASP A N   1 
ATOM   790  C CA  . ASP A 1 102 ? 140.113 139.896 90.161  1.00 116.13 ? 103 ASP A CA  1 
ATOM   791  C C   . ASP A 1 102 ? 141.585 139.487 89.994  1.00 118.98 ? 103 ASP A C   1 
ATOM   792  O O   . ASP A 1 102 ? 142.372 140.208 89.376  1.00 115.95 ? 103 ASP A O   1 
ATOM   793  C CB  . ASP A 1 102 ? 139.866 141.368 89.739  1.00 124.08 ? 103 ASP A CB  1 
ATOM   794  C CG  . ASP A 1 102 ? 140.584 142.437 90.581  1.00 131.74 ? 103 ASP A CG  1 
ATOM   795  O OD1 . ASP A 1 102 ? 141.308 142.165 91.543  1.00 124.15 ? 103 ASP A OD1 1 
ATOM   796  O OD2 . ASP A 1 102 ? 140.402 143.624 90.240  1.00 140.10 ? 103 ASP A OD2 1 
ATOM   797  N N   . ASP A 1 103 ? 141.926 138.297 90.487  1.00 123.47 ? 104 ASP A N   1 
ATOM   798  C CA  . ASP A 1 103 ? 143.243 137.677 90.383  1.00 120.98 ? 104 ASP A CA  1 
ATOM   799  C C   . ASP A 1 103 ? 143.028 136.194 90.101  1.00 122.54 ? 104 ASP A C   1 
ATOM   800  O O   . ASP A 1 103 ? 141.947 135.773 89.677  1.00 119.18 ? 104 ASP A O   1 
ATOM   801  C CB  . ASP A 1 103 ? 144.077 137.881 91.657  1.00 122.62 ? 104 ASP A CB  1 
ATOM   802  C CG  . ASP A 1 103 ? 144.548 139.310 91.842  1.00 130.53 ? 104 ASP A CG  1 
ATOM   803  O OD1 . ASP A 1 103 ? 144.777 140.010 90.837  1.00 132.87 ? 104 ASP A OD1 1 
ATOM   804  O OD2 . ASP A 1 103 ? 144.693 139.736 93.007  1.00 131.06 ? 104 ASP A OD2 1 
ATOM   805  N N   . GLY A 1 104 ? 144.063 135.393 90.337  1.00 126.22 ? 105 GLY A N   1 
ATOM   806  C CA  . GLY A 1 104 ? 143.991 133.965 90.114  1.00 127.21 ? 105 GLY A CA  1 
ATOM   807  C C   . GLY A 1 104 ? 143.343 133.217 91.265  1.00 125.44 ? 105 GLY A C   1 
ATOM   808  O O   . GLY A 1 104 ? 142.697 133.787 92.145  1.00 125.45 ? 105 GLY A O   1 
ATOM   809  N N   . ASN A 1 105 ? 143.528 131.899 91.244  1.00 124.00 ? 106 ASN A N   1 
ATOM   810  C CA  . ASN A 1 105 ? 142.866 130.997 92.175  1.00 123.76 ? 106 ASN A CA  1 
ATOM   811  C C   . ASN A 1 105 ? 143.895 130.023 92.734  1.00 126.60 ? 106 ASN A C   1 
ATOM   812  O O   . ASN A 1 105 ? 144.843 129.637 92.041  1.00 126.88 ? 106 ASN A O   1 
ATOM   813  C CB  . ASN A 1 105 ? 141.714 130.246 91.460  1.00 125.59 ? 106 ASN A CB  1 
ATOM   814  C CG  . ASN A 1 105 ? 140.950 129.281 92.366  1.00 123.30 ? 106 ASN A CG  1 
ATOM   815  O OD1 . ASN A 1 105 ? 141.087 129.287 93.588  1.00 116.14 ? 106 ASN A OD1 1 
ATOM   816  N ND2 . ASN A 1 105 ? 140.140 128.432 91.747  1.00 128.02 ? 106 ASN A ND2 1 
ATOM   817  N N   . TYR A 1 106 ? 143.700 129.631 93.995  1.00 122.31 ? 107 TYR A N   1 
ATOM   818  C CA  . TYR A 1 106 ? 144.533 128.632 94.654  1.00 117.14 ? 107 TYR A CA  1 
ATOM   819  C C   . TYR A 1 106 ? 143.711 127.385 94.948  1.00 117.25 ? 107 TYR A C   1 
ATOM   820  O O   . TYR A 1 106 ? 142.579 127.484 95.436  1.00 115.85 ? 107 TYR A O   1 
ATOM   821  C CB  . TYR A 1 106 ? 145.100 129.150 95.975  1.00 114.78 ? 107 TYR A CB  1 
ATOM   822  C CG  . TYR A 1 106 ? 146.346 129.990 95.916  1.00 114.90 ? 107 TYR A CG  1 
ATOM   823  C CD1 . TYR A 1 106 ? 147.310 129.782 94.944  1.00 121.30 ? 107 TYR A CD1 1 
ATOM   824  C CD2 . TYR A 1 106 ? 146.564 130.985 96.862  1.00 105.93 ? 107 TYR A CD2 1 
ATOM   825  C CE1 . TYR A 1 106 ? 148.454 130.550 94.910  1.00 124.37 ? 107 TYR A CE1 1 
ATOM   826  C CE2 . TYR A 1 106 ? 147.700 131.759 96.835  1.00 104.71 ? 107 TYR A CE2 1 
ATOM   827  C CZ  . TYR A 1 106 ? 148.643 131.538 95.857  1.00 120.66 ? 107 TYR A CZ  1 
ATOM   828  O OH  . TYR A 1 106 ? 149.781 132.310 95.825  1.00 130.42 ? 107 TYR A OH  1 
ATOM   829  N N   . LYS A 1 107 ? 144.292 126.220 94.676  1.00 114.37 ? 108 LYS A N   1 
ATOM   830  C CA  . LYS A 1 107 ? 143.780 124.941 95.151  1.00 110.33 ? 108 LYS A CA  1 
ATOM   831  C C   . LYS A 1 107 ? 144.786 124.352 96.128  1.00 109.83 ? 108 LYS A C   1 
ATOM   832  O O   . LYS A 1 107 ? 145.977 124.255 95.813  1.00 109.02 ? 108 LYS A O   1 
ATOM   833  C CB  . LYS A 1 107 ? 143.523 123.959 94.004  1.00 108.14 ? 108 LYS A CB  1 
ATOM   834  C CG  . LYS A 1 107 ? 142.169 124.096 93.308  1.00 108.32 ? 108 LYS A CG  1 
ATOM   835  C CD  . LYS A 1 107 ? 142.088 125.295 92.384  1.00 119.69 ? 108 LYS A CD  1 
ATOM   836  C CE  . LYS A 1 107 ? 142.974 125.093 91.172  1.00 123.64 ? 108 LYS A CE  1 
ATOM   837  N NZ  . LYS A 1 107 ? 142.858 126.222 90.221  1.00 128.37 ? 108 LYS A NZ  1 
ATOM   838  N N   . THR A 1 108 ? 144.303 123.963 97.307  1.00 106.91 ? 109 THR A N   1 
ATOM   839  C CA  . THR A 1 108 ? 145.137 123.522 98.415  1.00 104.35 ? 109 THR A CA  1 
ATOM   840  C C   . THR A 1 108 ? 144.702 122.137 98.869  1.00 105.35 ? 109 THR A C   1 
ATOM   841  O O   . THR A 1 108 ? 143.510 121.900 99.088  1.00 108.35 ? 109 THR A O   1 
ATOM   842  C CB  . THR A 1 108 ? 145.042 124.507 99.586  1.00 107.95 ? 109 THR A CB  1 
ATOM   843  O OG1 . THR A 1 108 ? 145.147 125.852 99.102  1.00 106.85 ? 109 THR A OG1 1 
ATOM   844  C CG2 . THR A 1 108 ? 146.106 124.234 100.629 1.00 107.16 ? 109 THR A CG2 1 
ATOM   845  N N   . ARG A 1 109 ? 145.669 121.235 99.027  1.00 105.46 ? 110 ARG A N   1 
ATOM   846  C CA  . ARG A 1 109 ? 145.417 119.888 99.526  1.00 106.42 ? 110 ARG A CA  1 
ATOM   847  C C   . ARG A 1 109 ? 146.419 119.598 100.633 1.00 105.52 ? 110 ARG A C   1 
ATOM   848  O O   . ARG A 1 109 ? 147.620 119.507 100.370 1.00 108.91 ? 110 ARG A O   1 
ATOM   849  C CB  . ARG A 1 109 ? 145.536 118.860 98.398  1.00 114.40 ? 110 ARG A CB  1 
ATOM   850  C CG  . ARG A 1 109 ? 145.310 117.418 98.815  1.00 123.92 ? 110 ARG A CG  1 
ATOM   851  C CD  . ARG A 1 109 ? 143.869 117.176 99.225  1.00 129.54 ? 110 ARG A CD  1 
ATOM   852  N NE  . ARG A 1 109 ? 143.646 115.792 99.625  1.00 151.99 ? 110 ARG A NE  1 
ATOM   853  C CZ  . ARG A 1 109 ? 143.291 114.821 98.795  1.00 162.87 ? 110 ARG A CZ  1 
ATOM   854  N NH1 . ARG A 1 109 ? 143.113 115.046 97.504  1.00 159.96 ? 110 ARG A NH1 1 
ATOM   855  N NH2 . ARG A 1 109 ? 143.111 113.592 99.272  1.00 166.39 ? 110 ARG A NH2 1 
ATOM   856  N N   . ALA A 1 110 ? 145.936 119.453 101.865 1.00 106.40 ? 111 ALA A N   1 
ATOM   857  C CA  . ALA A 1 110 ? 146.806 119.344 103.025 1.00 104.46 ? 111 ALA A CA  1 
ATOM   858  C C   . ALA A 1 110 ? 146.455 118.113 103.848 1.00 108.10 ? 111 ALA A C   1 
ATOM   859  O O   . ALA A 1 110 ? 145.281 117.809 104.078 1.00 117.39 ? 111 ALA A O   1 
ATOM   860  C CB  . ALA A 1 110 ? 146.715 120.595 103.907 1.00 105.73 ? 111 ALA A CB  1 
ATOM   861  N N   . GLU A 1 111 ? 147.499 117.425 104.303 1.00 109.27 ? 112 GLU A N   1 
ATOM   862  C CA  . GLU A 1 111 ? 147.393 116.235 105.139 1.00 109.07 ? 112 GLU A CA  1 
ATOM   863  C C   . GLU A 1 111 ? 147.975 116.547 106.507 1.00 114.62 ? 112 GLU A C   1 
ATOM   864  O O   . GLU A 1 111 ? 149.082 117.084 106.593 1.00 119.77 ? 112 GLU A O   1 
ATOM   865  C CB  . GLU A 1 111 ? 148.150 115.057 104.512 1.00 114.61 ? 112 GLU A CB  1 
ATOM   866  C CG  . GLU A 1 111 ? 148.078 113.752 105.295 1.00 126.93 ? 112 GLU A CG  1 
ATOM   867  C CD  . GLU A 1 111 ? 146.695 113.142 105.319 1.00 128.80 ? 112 GLU A CD  1 
ATOM   868  O OE1 . GLU A 1 111 ? 145.926 113.384 104.369 1.00 126.48 ? 112 GLU A OE1 1 
ATOM   869  O OE2 . GLU A 1 111 ? 146.374 112.423 106.288 1.00 125.30 ? 112 GLU A OE2 1 
ATOM   870  N N   . VAL A 1 112 ? 147.251 116.204 107.572 1.00 110.14 ? 113 VAL A N   1 
ATOM   871  C CA  . VAL A 1 112 ? 147.722 116.409 108.938 1.00 110.88 ? 113 VAL A CA  1 
ATOM   872  C C   . VAL A 1 112 ? 147.835 115.047 109.609 1.00 119.28 ? 113 VAL A C   1 
ATOM   873  O O   . VAL A 1 112 ? 146.827 114.340 109.756 1.00 125.09 ? 113 VAL A O   1 
ATOM   874  C CB  . VAL A 1 112 ? 146.785 117.330 109.734 1.00 106.24 ? 113 VAL A CB  1 
ATOM   875  C CG1 . VAL A 1 112 ? 147.286 117.489 111.153 1.00 108.97 ? 113 VAL A CG1 1 
ATOM   876  C CG2 . VAL A 1 112 ? 146.652 118.682 109.055 1.00 107.12 ? 113 VAL A CG2 1 
ATOM   877  N N   . LYS A 1 113 ? 149.053 114.689 110.029 1.00 124.30 ? 114 LYS A N   1 
ATOM   878  C CA  . LYS A 1 113 ? 149.318 113.406 110.664 1.00 122.64 ? 114 LYS A CA  1 
ATOM   879  C C   . LYS A 1 113 ? 150.081 113.620 111.963 1.00 118.91 ? 114 LYS A C   1 
ATOM   880  O O   . LYS A 1 113 ? 150.881 114.550 112.088 1.00 118.58 ? 114 LYS A O   1 
ATOM   881  C CB  . LYS A 1 113 ? 150.124 112.466 109.757 1.00 131.35 ? 114 LYS A CB  1 
ATOM   882  C CG  . LYS A 1 113 ? 149.424 112.059 108.475 1.00 128.11 ? 114 LYS A CG  1 
ATOM   883  C CD  . LYS A 1 113 ? 150.264 111.056 107.703 1.00 135.18 ? 114 LYS A CD  1 
ATOM   884  C CE  . LYS A 1 113 ? 151.516 111.702 107.133 1.00 132.49 ? 114 LYS A CE  1 
ATOM   885  N NZ  . LYS A 1 113 ? 151.201 112.716 106.095 1.00 132.14 ? 114 LYS A NZ  1 
ATOM   886  N N   . PHE A 1 114 ? 149.849 112.723 112.919 1.00 122.64 ? 115 PHE A N   1 
ATOM   887  C CA  . PHE A 1 114 ? 150.375 112.843 114.278 1.00 127.19 ? 115 PHE A CA  1 
ATOM   888  C C   . PHE A 1 114 ? 151.356 111.698 114.510 1.00 129.14 ? 115 PHE A C   1 
ATOM   889  O O   . PHE A 1 114 ? 150.954 110.590 114.875 1.00 130.77 ? 115 PHE A O   1 
ATOM   890  C CB  . PHE A 1 114 ? 149.227 112.814 115.281 1.00 125.95 ? 115 PHE A CB  1 
ATOM   891  C CG  . PHE A 1 114 ? 149.646 113.018 116.707 1.00 121.31 ? 115 PHE A CG  1 
ATOM   892  C CD1 . PHE A 1 114 ? 149.968 114.283 117.171 1.00 121.77 ? 115 PHE A CD1 1 
ATOM   893  C CD2 . PHE A 1 114 ? 149.700 111.950 117.588 1.00 127.17 ? 115 PHE A CD2 1 
ATOM   894  C CE1 . PHE A 1 114 ? 150.345 114.480 118.486 1.00 124.28 ? 115 PHE A CE1 1 
ATOM   895  C CE2 . PHE A 1 114 ? 150.079 112.138 118.905 1.00 132.27 ? 115 PHE A CE2 1 
ATOM   896  C CZ  . PHE A 1 114 ? 150.402 113.406 119.354 1.00 127.26 ? 115 PHE A CZ  1 
ATOM   897  N N   . GLU A 1 115 ? 152.643 111.959 114.299 1.00 127.83 ? 116 GLU A N   1 
ATOM   898  C CA  . GLU A 1 115 ? 153.673 110.933 114.386 1.00 126.70 ? 116 GLU A CA  1 
ATOM   899  C C   . GLU A 1 115 ? 154.553 111.220 115.595 1.00 129.25 ? 116 GLU A C   1 
ATOM   900  O O   . GLU A 1 115 ? 155.224 112.257 115.647 1.00 134.34 ? 116 GLU A O   1 
ATOM   901  C CB  . GLU A 1 115 ? 154.500 110.896 113.103 1.00 131.41 ? 116 GLU A CB  1 
ATOM   902  C CG  . GLU A 1 115 ? 153.651 110.889 111.843 1.00 126.36 ? 116 GLU A CG  1 
ATOM   903  C CD  . GLU A 1 115 ? 154.474 110.727 110.584 1.00 135.23 ? 116 GLU A CD  1 
ATOM   904  O OE1 . GLU A 1 115 ? 155.708 110.576 110.693 1.00 141.17 ? 116 GLU A OE1 1 
ATOM   905  O OE2 . GLU A 1 115 ? 153.887 110.755 109.482 1.00 135.40 ? 116 GLU A OE2 1 
ATOM   906  N N   . GLY A 1 116 ? 154.566 110.290 116.546 1.00 129.22 ? 117 GLY A N   1 
ATOM   907  C CA  . GLY A 1 116 ? 155.264 110.531 117.798 1.00 134.84 ? 117 GLY A CA  1 
ATOM   908  C C   . GLY A 1 116 ? 154.589 111.650 118.564 1.00 134.26 ? 117 GLY A C   1 
ATOM   909  O O   . GLY A 1 116 ? 153.392 111.598 118.866 1.00 130.67 ? 117 GLY A O   1 
ATOM   910  N N   . ASP A 1 117 ? 155.364 112.681 118.881 1.00 136.16 ? 118 ASP A N   1 
ATOM   911  C CA  . ASP A 1 117 ? 154.824 113.917 119.422 1.00 132.44 ? 118 ASP A CA  1 
ATOM   912  C C   . ASP A 1 117 ? 154.761 115.009 118.361 1.00 130.30 ? 118 ASP A C   1 
ATOM   913  O O   . ASP A 1 117 ? 154.178 116.070 118.604 1.00 123.68 ? 118 ASP A O   1 
ATOM   914  C CB  . ASP A 1 117 ? 155.674 114.377 120.617 1.00 137.89 ? 118 ASP A CB  1 
ATOM   915  C CG  . ASP A 1 117 ? 154.959 115.386 121.505 1.00 139.70 ? 118 ASP A CG  1 
ATOM   916  O OD1 . ASP A 1 117 ? 153.727 115.543 121.370 1.00 137.63 ? 118 ASP A OD1 1 
ATOM   917  O OD2 . ASP A 1 117 ? 155.633 116.024 122.341 1.00 142.99 ? 118 ASP A OD2 1 
ATOM   918  N N   . THR A 1 118 ? 155.320 114.763 117.179 1.00 140.03 ? 119 THR A N   1 
ATOM   919  C CA  . THR A 1 118 ? 155.389 115.767 116.127 1.00 139.53 ? 119 THR A CA  1 
ATOM   920  C C   . THR A 1 118 ? 154.167 115.662 115.227 1.00 137.34 ? 119 THR A C   1 
ATOM   921  O O   . THR A 1 118 ? 153.852 114.584 114.711 1.00 135.00 ? 119 THR A O   1 
ATOM   922  C CB  . THR A 1 118 ? 156.664 115.614 115.296 1.00 134.46 ? 119 THR A CB  1 
ATOM   923  O OG1 . THR A 1 118 ? 156.673 114.330 114.661 1.00 138.73 ? 119 THR A OG1 1 
ATOM   924  C CG2 . THR A 1 118 ? 157.892 115.745 116.182 1.00 130.42 ? 119 THR A CG2 1 
ATOM   925  N N   . LEU A 1 119 ? 153.480 116.779 115.045 1.00 135.88 ? 120 LEU A N   1 
ATOM   926  C CA  . LEU A 1 119 ? 152.383 116.869 114.098 1.00 133.90 ? 120 LEU A CA  1 
ATOM   927  C C   . LEU A 1 119 ? 152.901 117.477 112.803 1.00 134.16 ? 120 LEU A C   1 
ATOM   928  O O   . LEU A 1 119 ? 153.416 118.599 112.799 1.00 129.18 ? 120 LEU A O   1 
ATOM   929  C CB  . LEU A 1 119 ? 151.244 117.710 114.663 1.00 128.19 ? 120 LEU A CB  1 
ATOM   930  C CG  . LEU A 1 119 ? 149.919 117.650 113.920 1.00 125.38 ? 120 LEU A CG  1 
ATOM   931  C CD1 . LEU A 1 119 ? 149.229 116.367 114.245 1.00 123.10 ? 120 LEU A CD1 1 
ATOM   932  C CD2 . LEU A 1 119 ? 149.058 118.834 114.273 1.00 129.53 ? 120 LEU A CD2 1 
ATOM   933  N N   . VAL A 1 120 ? 152.765 116.733 111.711 1.00 134.35 ? 121 VAL A N   1 
ATOM   934  C CA  . VAL A 1 120 ? 153.290 117.131 110.414 1.00 124.07 ? 121 VAL A CA  1 
ATOM   935  C C   . VAL A 1 120 ? 152.114 117.322 109.471 1.00 119.93 ? 121 VAL A C   1 
ATOM   936  O O   . VAL A 1 120 ? 151.300 116.407 109.291 1.00 123.86 ? 121 VAL A O   1 
ATOM   937  C CB  . VAL A 1 120 ? 154.276 116.092 109.857 1.00 124.09 ? 121 VAL A CB  1 
ATOM   938  C CG1 . VAL A 1 120 ? 154.697 116.453 108.439 1.00 125.15 ? 121 VAL A CG1 1 
ATOM   939  C CG2 . VAL A 1 120 ? 155.489 115.975 110.765 1.00 128.35 ? 121 VAL A CG2 1 
ATOM   940  N N   . ASN A 1 121 ? 152.015 118.509 108.885 1.00 116.29 ? 122 ASN A N   1 
ATOM   941  C CA  . ASN A 1 121 ? 151.080 118.763 107.795 1.00 118.51 ? 122 ASN A CA  1 
ATOM   942  C C   . ASN A 1 121 ? 151.852 119.009 106.497 1.00 115.00 ? 122 ASN A C   1 
ATOM   943  O O   . ASN A 1 121 ? 152.844 119.741 106.462 1.00 113.92 ? 122 ASN A O   1 
ATOM   944  C CB  . ASN A 1 121 ? 150.090 119.880 108.153 1.00 121.13 ? 122 ASN A CB  1 
ATOM   945  C CG  . ASN A 1 121 ? 150.749 121.195 108.553 1.00 119.35 ? 122 ASN A CG  1 
ATOM   946  O OD1 . ASN A 1 121 ? 151.961 121.351 108.530 1.00 124.20 ? 122 ASN A OD1 1 
ATOM   947  N ND2 . ASN A 1 121 ? 149.918 122.162 108.921 1.00 117.16 ? 122 ASN A ND2 1 
ATOM   948  N N   . ARG A 1 122 ? 151.423 118.321 105.448 1.00 115.88 ? 123 ARG A N   1 
ATOM   949  C CA  . ARG A 1 122 ? 152.030 118.433 104.131 1.00 116.78 ? 123 ARG A CA  1 
ATOM   950  C C   . ARG A 1 122 ? 151.019 119.043 103.172 1.00 114.09 ? 123 ARG A C   1 
ATOM   951  O O   . ARG A 1 122 ? 149.880 118.575 103.083 1.00 121.77 ? 123 ARG A O   1 
ATOM   952  C CB  . ARG A 1 122 ? 152.498 117.066 103.631 1.00 122.88 ? 123 ARG A CB  1 
ATOM   953  C CG  . ARG A 1 122 ? 153.812 117.108 102.868 1.00 129.66 ? 123 ARG A CG  1 
ATOM   954  C CD  . ARG A 1 122 ? 154.394 115.718 102.684 1.00 133.26 ? 123 ARG A CD  1 
ATOM   955  N NE  . ARG A 1 122 ? 155.202 115.320 103.829 1.00 136.85 ? 123 ARG A NE  1 
ATOM   956  C CZ  . ARG A 1 122 ? 154.857 114.379 104.696 1.00 132.50 ? 123 ARG A CZ  1 
ATOM   957  N NH1 . ARG A 1 122 ? 153.719 113.715 104.578 1.00 126.34 ? 123 ARG A NH1 1 
ATOM   958  N NH2 . ARG A 1 122 ? 155.672 114.097 105.709 1.00 132.99 ? 123 ARG A NH2 1 
ATOM   959  N N   . ILE A 1 123 ? 151.437 120.088 102.465 1.00 108.10 ? 124 ILE A N   1 
ATOM   960  C CA  . ILE A 1 123 ? 150.528 120.943 101.716 1.00 109.74 ? 124 ILE A CA  1 
ATOM   961  C C   . ILE A 1 123 ? 150.958 120.973 100.256 1.00 114.69 ? 124 ILE A C   1 
ATOM   962  O O   . ILE A 1 123 ? 152.135 121.169 99.939  1.00 121.48 ? 124 ILE A O   1 
ATOM   963  C CB  . ILE A 1 123 ? 150.503 122.368 102.312 1.00 113.58 ? 124 ILE A CB  1 
ATOM   964  C CG1 . ILE A 1 123 ? 150.039 122.336 103.768 1.00 114.70 ? 124 ILE A CG1 1 
ATOM   965  C CG2 . ILE A 1 123 ? 149.559 123.255 101.537 1.00 116.23 ? 124 ILE A CG2 1 
ATOM   966  C CD1 . ILE A 1 123 ? 150.248 123.637 104.494 1.00 111.34 ? 124 ILE A CD1 1 
ATOM   967  N N   . GLU A 1 124 ? 149.991 120.769 99.362  1.00 111.52 ? 125 GLU A N   1 
ATOM   968  C CA  . GLU A 1 124 ? 150.201 120.888 97.927  1.00 111.18 ? 125 GLU A CA  1 
ATOM   969  C C   . GLU A 1 124 ? 149.344 122.037 97.421  1.00 112.63 ? 125 GLU A C   1 
ATOM   970  O O   . GLU A 1 124 ? 148.139 122.079 97.692  1.00 121.54 ? 125 GLU A O   1 
ATOM   971  C CB  . GLU A 1 124 ? 149.850 119.572 97.213  1.00 116.40 ? 125 GLU A CB  1 
ATOM   972  C CG  . GLU A 1 124 ? 150.255 119.470 95.740  1.00 122.78 ? 125 GLU A CG  1 
ATOM   973  C CD  . GLU A 1 124 ? 149.235 120.063 94.786  1.00 129.14 ? 125 GLU A CD  1 
ATOM   974  O OE1 . GLU A 1 124 ? 148.033 120.064 95.124  1.00 126.34 ? 125 GLU A OE1 1 
ATOM   975  O OE2 . GLU A 1 124 ? 149.637 120.524 93.697  1.00 129.35 ? 125 GLU A OE2 1 
ATOM   976  N N   . LEU A 1 125 ? 149.966 122.963 96.692  1.00 112.14 ? 126 LEU A N   1 
ATOM   977  C CA  . LEU A 1 125 ? 149.301 124.147 96.169  1.00 116.89 ? 126 LEU A CA  1 
ATOM   978  C C   . LEU A 1 125 ? 149.319 124.146 94.648  1.00 118.73 ? 126 LEU A C   1 
ATOM   979  O O   . LEU A 1 125 ? 150.240 123.618 94.020  1.00 122.27 ? 126 LEU A O   1 
ATOM   980  C CB  . LEU A 1 125 ? 149.966 125.438 96.662  1.00 118.49 ? 126 LEU A CB  1 
ATOM   981  C CG  . LEU A 1 125 ? 149.909 125.826 98.135  1.00 120.81 ? 126 LEU A CG  1 
ATOM   982  C CD1 . LEU A 1 125 ? 150.771 127.048 98.365  1.00 123.13 ? 126 LEU A CD1 1 
ATOM   983  C CD2 . LEU A 1 125 ? 148.481 126.128 98.514  1.00 115.84 ? 126 LEU A CD2 1 
ATOM   984  N N   . LYS A 1 126 ? 148.285 124.747 94.065  1.00 118.37 ? 127 LYS A N   1 
ATOM   985  C CA  . LYS A 1 126 ? 148.244 125.015 92.633  1.00 124.15 ? 127 LYS A CA  1 
ATOM   986  C C   . LYS A 1 126 ? 147.586 126.365 92.399  1.00 125.87 ? 127 LYS A C   1 
ATOM   987  O O   . LYS A 1 126 ? 146.433 126.569 92.788  1.00 127.71 ? 127 LYS A O   1 
ATOM   988  C CB  . LYS A 1 126 ? 147.488 123.918 91.879  1.00 129.27 ? 127 LYS A CB  1 
ATOM   989  C CG  . LYS A 1 126 ? 147.431 124.139 90.377  1.00 130.12 ? 127 LYS A CG  1 
ATOM   990  C CD  . LYS A 1 126 ? 148.803 123.971 89.747  1.00 136.15 ? 127 LYS A CD  1 
ATOM   991  C CE  . LYS A 1 126 ? 148.735 124.086 88.233  1.00 138.70 ? 127 LYS A CE  1 
ATOM   992  N NZ  . LYS A 1 126 ? 150.085 123.989 87.612  1.00 139.10 ? 127 LYS A NZ  1 
ATOM   993  N N   . GLY A 1 127 ? 148.308 127.276 91.763  1.00 128.18 ? 128 GLY A N   1 
ATOM   994  C CA  . GLY A 1 127 ? 147.812 128.620 91.504  1.00 130.47 ? 128 GLY A CA  1 
ATOM   995  C C   . GLY A 1 127 ? 147.630 128.851 90.017  1.00 126.82 ? 128 GLY A C   1 
ATOM   996  O O   . GLY A 1 127 ? 148.424 128.368 89.208  1.00 128.77 ? 128 GLY A O   1 
ATOM   997  N N   . ILE A 1 128 ? 146.581 129.590 89.662  1.00 123.64 ? 129 ILE A N   1 
ATOM   998  C CA  . ILE A 1 128 ? 146.220 129.781 88.262  1.00 122.59 ? 129 ILE A CA  1 
ATOM   999  C C   . ILE A 1 128 ? 145.854 131.244 88.011  1.00 130.71 ? 129 ILE A C   1 
ATOM   1000 O O   . ILE A 1 128 ? 145.283 131.914 88.883  1.00 135.82 ? 129 ILE A O   1 
ATOM   1001 C CB  . ILE A 1 128 ? 145.083 128.809 87.846  1.00 123.58 ? 129 ILE A CB  1 
ATOM   1002 C CG1 . ILE A 1 128 ? 144.820 128.839 86.335  1.00 124.87 ? 129 ILE A CG1 1 
ATOM   1003 C CG2 . ILE A 1 128 ? 143.806 129.050 88.635  1.00 125.75 ? 129 ILE A CG2 1 
ATOM   1004 C CD1 . ILE A 1 128 ? 146.049 128.571 85.493  1.00 124.90 ? 129 ILE A CD1 1 
ATOM   1005 N N   . ASP A 1 129 ? 146.273 131.745 86.838  1.00 126.87 ? 130 ASP A N   1 
ATOM   1006 C CA  . ASP A 1 129 ? 145.867 133.023 86.217  1.00 124.58 ? 130 ASP A CA  1 
ATOM   1007 C C   . ASP A 1 129 ? 146.121 134.243 87.111  1.00 125.78 ? 130 ASP A C   1 
ATOM   1008 O O   . ASP A 1 129 ? 145.381 135.229 87.095  1.00 126.14 ? 130 ASP A O   1 
ATOM   1009 C CB  . ASP A 1 129 ? 144.419 132.952 85.671  1.00 124.72 ? 130 ASP A CB  1 
ATOM   1010 C CG  . ASP A 1 129 ? 143.323 132.997 86.742  1.00 127.15 ? 130 ASP A CG  1 
ATOM   1011 O OD1 . ASP A 1 129 ? 142.821 134.095 87.060  1.00 131.32 ? 130 ASP A OD1 1 
ATOM   1012 O OD2 . ASP A 1 129 ? 142.917 131.921 87.225  1.00 127.95 ? 130 ASP A OD2 1 
ATOM   1013 N N   . PHE A 1 130 ? 147.241 134.214 87.832  1.00 130.23 ? 131 PHE A N   1 
ATOM   1014 C CA  . PHE A 1 130 ? 147.739 135.410 88.505  1.00 131.82 ? 131 PHE A CA  1 
ATOM   1015 C C   . PHE A 1 130 ? 148.200 136.434 87.473  1.00 135.59 ? 131 PHE A C   1 
ATOM   1016 O O   . PHE A 1 130 ? 148.961 136.103 86.558  1.00 136.44 ? 131 PHE A O   1 
ATOM   1017 C CB  . PHE A 1 130 ? 148.891 135.059 89.444  1.00 135.33 ? 131 PHE A CB  1 
ATOM   1018 C CG  . PHE A 1 130 ? 148.457 134.541 90.783  1.00 138.42 ? 131 PHE A CG  1 
ATOM   1019 C CD1 . PHE A 1 130 ? 147.202 134.839 91.284  1.00 129.45 ? 131 PHE A CD1 1 
ATOM   1020 C CD2 . PHE A 1 130 ? 149.314 133.764 91.547  1.00 139.25 ? 131 PHE A CD2 1 
ATOM   1021 C CE1 . PHE A 1 130 ? 146.797 134.363 92.516  1.00 126.91 ? 131 PHE A CE1 1 
ATOM   1022 C CE2 . PHE A 1 130 ? 148.919 133.288 92.783  1.00 134.91 ? 131 PHE A CE2 1 
ATOM   1023 C CZ  . PHE A 1 130 ? 147.657 133.589 93.267  1.00 129.73 ? 131 PHE A CZ  1 
ATOM   1024 N N   . LYS A 1 131 ? 147.740 137.673 87.619  1.00 139.79 ? 132 LYS A N   1 
ATOM   1025 C CA  . LYS A 1 131 ? 148.148 138.738 86.711  1.00 137.64 ? 132 LYS A CA  1 
ATOM   1026 C C   . LYS A 1 131 ? 149.554 139.211 87.060  1.00 139.16 ? 132 LYS A C   1 
ATOM   1027 O O   . LYS A 1 131 ? 149.921 139.302 88.235  1.00 138.92 ? 132 LYS A O   1 
ATOM   1028 C CB  . LYS A 1 131 ? 147.176 139.927 86.753  1.00 134.69 ? 132 LYS A CB  1 
ATOM   1029 C CG  . LYS A 1 131 ? 145.674 139.678 87.044  1.00 129.31 ? 132 LYS A CG  1 
ATOM   1030 C CD  . LYS A 1 131 ? 145.011 138.599 86.173  1.00 134.76 ? 132 LYS A CD  1 
ATOM   1031 C CE  . LYS A 1 131 ? 143.499 138.734 86.177  1.00 130.27 ? 132 LYS A CE  1 
ATOM   1032 N NZ  . LYS A 1 131 ? 142.850 137.704 85.321  1.00 122.50 ? 132 LYS A NZ  1 
ATOM   1033 N N   . GLU A 1 132 ? 150.344 139.507 86.023  1.00 145.20 ? 133 GLU A N   1 
ATOM   1034 C CA  . GLU A 1 132 ? 151.728 139.928 86.230  1.00 151.25 ? 133 GLU A CA  1 
ATOM   1035 C C   . GLU A 1 132 ? 151.801 141.313 86.861  1.00 148.33 ? 133 GLU A C   1 
ATOM   1036 O O   . GLU A 1 132 ? 152.655 141.569 87.718  1.00 144.66 ? 133 GLU A O   1 
ATOM   1037 C CB  . GLU A 1 132 ? 152.485 139.905 84.901  1.00 155.07 ? 133 GLU A CB  1 
ATOM   1038 C CG  . GLU A 1 132 ? 152.460 138.562 84.188  1.00 156.63 ? 133 GLU A CG  1 
ATOM   1039 C CD  . GLU A 1 132 ? 153.080 137.449 85.009  1.00 157.03 ? 133 GLU A CD  1 
ATOM   1040 O OE1 . GLU A 1 132 ? 154.172 137.663 85.576  1.00 158.98 ? 133 GLU A OE1 1 
ATOM   1041 O OE2 . GLU A 1 132 ? 152.474 136.360 85.088  1.00 149.28 ? 133 GLU A OE2 1 
ATOM   1042 N N   . ASP A 1 133 ? 150.915 142.216 86.453  1.00 150.92 ? 134 ASP A N   1 
ATOM   1043 C CA  . ASP A 1 133 ? 150.864 143.565 86.995  1.00 155.89 ? 134 ASP A CA  1 
ATOM   1044 C C   . ASP A 1 133 ? 149.877 143.698 88.148  1.00 156.11 ? 134 ASP A C   1 
ATOM   1045 O O   . ASP A 1 133 ? 149.606 144.819 88.589  1.00 153.87 ? 134 ASP A O   1 
ATOM   1046 C CB  . ASP A 1 133 ? 150.511 144.564 85.890  1.00 157.73 ? 134 ASP A CB  1 
ATOM   1047 C CG  . ASP A 1 133 ? 149.156 144.290 85.269  1.00 155.37 ? 134 ASP A CG  1 
ATOM   1048 O OD1 . ASP A 1 133 ? 148.811 143.103 85.089  1.00 150.19 ? 134 ASP A OD1 1 
ATOM   1049 O OD2 . ASP A 1 133 ? 148.434 145.262 84.960  1.00 157.04 ? 134 ASP A OD2 1 
ATOM   1050 N N   . GLY A 1 134 ? 149.340 142.588 88.643  1.00 152.56 ? 135 GLY A N   1 
ATOM   1051 C CA  . GLY A 1 134 ? 148.366 142.626 89.711  1.00 144.47 ? 135 GLY A CA  1 
ATOM   1052 C C   . GLY A 1 134 ? 149.004 142.829 91.075  1.00 140.86 ? 135 GLY A C   1 
ATOM   1053 O O   . GLY A 1 134 ? 150.186 143.141 91.219  1.00 142.26 ? 135 GLY A O   1 
ATOM   1054 N N   . ASN A 1 135 ? 148.176 142.649 92.106  1.00 133.20 ? 136 ASN A N   1 
ATOM   1055 C CA  . ASN A 1 135 ? 148.642 142.859 93.473  1.00 123.58 ? 136 ASN A CA  1 
ATOM   1056 C C   . ASN A 1 135 ? 149.513 141.704 93.953  1.00 126.04 ? 136 ASN A C   1 
ATOM   1057 O O   . ASN A 1 135 ? 150.444 141.910 94.739  1.00 125.35 ? 136 ASN A O   1 
ATOM   1058 C CB  . ASN A 1 135 ? 147.452 143.052 94.412  1.00 123.14 ? 136 ASN A CB  1 
ATOM   1059 C CG  . ASN A 1 135 ? 146.570 144.216 94.009  1.00 127.12 ? 136 ASN A CG  1 
ATOM   1060 O OD1 . ASN A 1 135 ? 145.370 144.220 94.281  1.00 123.54 ? 136 ASN A OD1 1 
ATOM   1061 N ND2 . ASN A 1 135 ? 147.165 145.223 93.379  1.00 128.13 ? 136 ASN A ND2 1 
ATOM   1062 N N   . ILE A 1 136 ? 149.227 140.486 93.493  1.00 128.45 ? 137 ILE A N   1 
ATOM   1063 C CA  . ILE A 1 136 ? 149.908 139.308 94.026  1.00 125.41 ? 137 ILE A CA  1 
ATOM   1064 C C   . ILE A 1 136 ? 151.316 139.197 93.453  1.00 127.00 ? 137 ILE A C   1 
ATOM   1065 O O   . ILE A 1 136 ? 152.304 139.151 94.194  1.00 130.57 ? 137 ILE A O   1 
ATOM   1066 C CB  . ILE A 1 136 ? 149.088 138.036 93.750  1.00 125.04 ? 137 ILE A CB  1 
ATOM   1067 C CG1 . ILE A 1 136 ? 147.619 138.248 94.123  1.00 121.88 ? 137 ILE A CG1 1 
ATOM   1068 C CG2 . ILE A 1 136 ? 149.665 136.857 94.513  1.00 123.52 ? 137 ILE A CG2 1 
ATOM   1069 C CD1 . ILE A 1 136 ? 147.393 138.577 95.589  1.00 118.39 ? 137 ILE A CD1 1 
ATOM   1070 N N   . LEU A 1 137 ? 151.430 139.150 92.125  1.00 128.89 ? 138 LEU A N   1 
ATOM   1071 C CA  . LEU A 1 137 ? 152.750 139.038 91.514  1.00 132.92 ? 138 LEU A CA  1 
ATOM   1072 C C   . LEU A 1 137 ? 153.510 140.356 91.566  1.00 134.44 ? 138 LEU A C   1 
ATOM   1073 O O   . LEU A 1 137 ? 154.745 140.359 91.531  1.00 133.34 ? 138 LEU A O   1 
ATOM   1074 C CB  . LEU A 1 137 ? 152.626 138.547 90.072  1.00 141.25 ? 138 LEU A CB  1 
ATOM   1075 C CG  . LEU A 1 137 ? 151.992 137.166 89.880  1.00 141.41 ? 138 LEU A CG  1 
ATOM   1076 C CD1 . LEU A 1 137 ? 152.088 136.735 88.427  1.00 143.47 ? 138 LEU A CD1 1 
ATOM   1077 C CD2 . LEU A 1 137 ? 152.635 136.130 90.792  1.00 137.39 ? 138 LEU A CD2 1 
ATOM   1078 N N   . GLY A 1 138 ? 152.800 141.477 91.661  1.00 135.19 ? 139 GLY A N   1 
ATOM   1079 C CA  . GLY A 1 138 ? 153.439 142.770 91.784  1.00 135.65 ? 139 GLY A CA  1 
ATOM   1080 C C   . GLY A 1 138 ? 153.990 143.096 93.152  1.00 133.82 ? 139 GLY A C   1 
ATOM   1081 O O   . GLY A 1 138 ? 154.680 144.112 93.287  1.00 134.58 ? 139 GLY A O   1 
ATOM   1082 N N   . HIS A 1 139 ? 153.693 142.255 94.154  1.00 131.07 ? 140 HIS A N   1 
ATOM   1083 C CA  . HIS A 1 139 ? 154.204 142.368 95.528  1.00 123.29 ? 140 HIS A CA  1 
ATOM   1084 C C   . HIS A 1 139 ? 153.834 143.706 96.165  1.00 123.00 ? 140 HIS A C   1 
ATOM   1085 O O   . HIS A 1 139 ? 154.652 144.348 96.827  1.00 130.96 ? 140 HIS A O   1 
ATOM   1086 C CB  . HIS A 1 139 ? 155.720 142.136 95.603  1.00 129.69 ? 140 HIS A CB  1 
ATOM   1087 C CG  . HIS A 1 139 ? 156.160 140.758 95.207  1.00 134.66 ? 140 HIS A CG  1 
ATOM   1088 N ND1 . HIS A 1 139 ? 155.775 140.150 94.031  1.00 134.62 ? 140 HIS A ND1 1 
ATOM   1089 C CD2 . HIS A 1 139 ? 156.962 139.869 95.841  1.00 136.94 ? 140 HIS A CD2 1 
ATOM   1090 C CE1 . HIS A 1 139 ? 156.319 138.949 93.958  1.00 136.67 ? 140 HIS A CE1 1 
ATOM   1091 N NE2 . HIS A 1 139 ? 157.044 138.754 95.044  1.00 139.66 ? 140 HIS A NE2 1 
ATOM   1092 N N   . LYS A 1 140 ? 152.589 144.130 95.967  1.00 122.53 ? 141 LYS A N   1 
ATOM   1093 C CA  . LYS A 1 140 ? 152.111 145.405 96.479  1.00 124.03 ? 141 LYS A CA  1 
ATOM   1094 C C   . LYS A 1 140 ? 151.472 145.293 97.857  1.00 120.28 ? 141 LYS A C   1 
ATOM   1095 O O   . LYS A 1 140 ? 150.750 146.207 98.266  1.00 122.89 ? 141 LYS A O   1 
ATOM   1096 C CB  . LYS A 1 140 ? 151.113 146.023 95.498  1.00 126.09 ? 141 LYS A CB  1 
ATOM   1097 C CG  . LYS A 1 140 ? 151.697 146.322 94.128  1.00 137.02 ? 141 LYS A CG  1 
ATOM   1098 C CD  . LYS A 1 140 ? 152.712 147.450 94.197  1.00 138.40 ? 141 LYS A CD  1 
ATOM   1099 C CE  . LYS A 1 140 ? 153.303 147.745 92.828  1.00 147.67 ? 141 LYS A CE  1 
ATOM   1100 N NZ  . LYS A 1 140 ? 152.294 148.330 91.903  1.00 154.21 ? 141 LYS A NZ  1 
ATOM   1101 N N   . LEU A 1 141 ? 151.718 144.204 98.581  1.00 110.07 ? 142 LEU A N   1 
ATOM   1102 C CA  . LEU A 1 141 ? 151.105 143.991 99.885  1.00 108.03 ? 142 LEU A CA  1 
ATOM   1103 C C   . LEU A 1 141 ? 152.073 144.360 101.002 1.00 111.54 ? 142 LEU A C   1 
ATOM   1104 O O   . LEU A 1 141 ? 153.274 144.090 100.915 1.00 111.93 ? 142 LEU A O   1 
ATOM   1105 C CB  . LEU A 1 141 ? 150.656 142.536 100.053 1.00 105.60 ? 142 LEU A CB  1 
ATOM   1106 C CG  . LEU A 1 141 ? 149.354 142.015 99.426  1.00 101.58 ? 142 LEU A CG  1 
ATOM   1107 C CD1 . LEU A 1 141 ? 149.418 141.874 97.915  1.00 110.70 ? 142 LEU A CD1 1 
ATOM   1108 C CD2 . LEU A 1 141 ? 148.988 140.685 100.060 1.00 105.70 ? 142 LEU A CD2 1 
ATOM   1109 N N   . GLU A 1 142 ? 151.537 144.982 102.050 1.00 112.02 ? 143 GLU A N   1 
ATOM   1110 C CA  . GLU A 1 142 ? 152.321 145.305 103.232 1.00 111.43 ? 143 GLU A CA  1 
ATOM   1111 C C   . GLU A 1 142 ? 152.676 144.042 104.010 1.00 109.80 ? 143 GLU A C   1 
ATOM   1112 O O   . GLU A 1 142 ? 152.064 142.983 103.847 1.00 111.83 ? 143 GLU A O   1 
ATOM   1113 C CB  . GLU A 1 142 ? 151.558 146.270 104.141 1.00 118.06 ? 143 GLU A CB  1 
ATOM   1114 C CG  . GLU A 1 142 ? 151.390 147.673 103.588 1.00 123.96 ? 143 GLU A CG  1 
ATOM   1115 C CD  . GLU A 1 142 ? 152.704 148.431 103.518 1.00 131.64 ? 143 GLU A CD  1 
ATOM   1116 O OE1 . GLU A 1 142 ? 153.578 148.189 104.378 1.00 127.72 ? 143 GLU A OE1 1 
ATOM   1117 O OE2 . GLU A 1 142 ? 152.864 149.273 102.613 1.00 135.85 ? 143 GLU A OE2 1 
ATOM   1118 N N   . TYR A 1 143 ? 153.683 144.167 104.874 1.00 103.27 ? 144 TYR A N   1 
ATOM   1119 C CA  . TYR A 1 143 ? 154.128 143.055 105.710 1.00 102.32 ? 144 TYR A CA  1 
ATOM   1120 C C   . TYR A 1 143 ? 153.355 143.118 107.025 1.00 107.87 ? 144 TYR A C   1 
ATOM   1121 O O   . TYR A 1 143 ? 153.895 143.417 108.090 1.00 113.16 ? 144 TYR A O   1 
ATOM   1122 C CB  . TYR A 1 143 ? 155.639 143.106 105.922 1.00 104.04 ? 144 TYR A CB  1 
ATOM   1123 C CG  . TYR A 1 143 ? 156.242 141.780 106.339 1.00 111.85 ? 144 TYR A CG  1 
ATOM   1124 C CD1 . TYR A 1 143 ? 156.348 141.429 107.681 1.00 108.80 ? 144 TYR A CD1 1 
ATOM   1125 C CD2 . TYR A 1 143 ? 156.692 140.873 105.387 1.00 110.17 ? 144 TYR A CD2 1 
ATOM   1126 C CE1 . TYR A 1 143 ? 156.892 140.218 108.061 1.00 108.04 ? 144 TYR A CE1 1 
ATOM   1127 C CE2 . TYR A 1 143 ? 157.237 139.660 105.759 1.00 107.75 ? 144 TYR A CE2 1 
ATOM   1128 C CZ  . TYR A 1 143 ? 157.334 139.339 107.096 1.00 113.58 ? 144 TYR A CZ  1 
ATOM   1129 O OH  . TYR A 1 143 ? 157.876 138.132 107.470 1.00 124.85 ? 144 TYR A OH  1 
ATOM   1130 N N   . ASN A 1 144 ? 152.059 142.842 106.932 1.00 101.17 ? 145 ASN A N   1 
ATOM   1131 C CA  . ASN A 1 144 ? 151.177 142.807 108.092 1.00 101.05 ? 145 ASN A CA  1 
ATOM   1132 C C   . ASN A 1 144 ? 150.019 141.864 107.792 1.00 105.31 ? 145 ASN A C   1 
ATOM   1133 O O   . ASN A 1 144 ? 149.721 141.567 106.633 1.00 115.58 ? 145 ASN A O   1 
ATOM   1134 C CB  . ASN A 1 144 ? 150.713 144.217 108.500 1.00 106.46 ? 145 ASN A CB  1 
ATOM   1135 C CG  . ASN A 1 144 ? 149.959 144.972 107.399 1.00 114.50 ? 145 ASN A CG  1 
ATOM   1136 O OD1 . ASN A 1 144 ? 149.668 144.454 106.321 1.00 121.18 ? 145 ASN A OD1 1 
ATOM   1137 N ND2 . ASN A 1 144 ? 149.643 146.229 107.687 1.00 115.22 ? 145 ASN A ND2 1 
ATOM   1138 N N   . TYR A 1 145 ? 149.379 141.381 108.853 1.00 102.80 ? 146 TYR A N   1 
ATOM   1139 C CA  . TYR A 1 145 ? 148.257 140.469 108.705 1.00 98.82  ? 146 TYR A CA  1 
ATOM   1140 C C   . TYR A 1 145 ? 147.329 140.681 109.892 1.00 93.77  ? 146 TYR A C   1 
ATOM   1141 O O   . TYR A 1 145 ? 147.774 140.983 111.002 1.00 91.57  ? 146 TYR A O   1 
ATOM   1142 C CB  . TYR A 1 145 ? 148.742 139.014 108.606 1.00 102.18 ? 146 TYR A CB  1 
ATOM   1143 C CG  . TYR A 1 145 ? 147.676 137.990 108.290 1.00 100.68 ? 146 TYR A CG  1 
ATOM   1144 C CD1 . TYR A 1 145 ? 147.184 137.861 106.996 1.00 103.22 ? 146 TYR A CD1 1 
ATOM   1145 C CD2 . TYR A 1 145 ? 147.190 137.131 109.264 1.00 104.77 ? 146 TYR A CD2 1 
ATOM   1146 C CE1 . TYR A 1 145 ? 146.223 136.921 106.686 1.00 106.40 ? 146 TYR A CE1 1 
ATOM   1147 C CE2 . TYR A 1 145 ? 146.225 136.185 108.964 1.00 103.58 ? 146 TYR A CE2 1 
ATOM   1148 C CZ  . TYR A 1 145 ? 145.748 136.087 107.673 1.00 104.76 ? 146 TYR A CZ  1 
ATOM   1149 O OH  . TYR A 1 145 ? 144.790 135.150 107.364 1.00 105.83 ? 146 TYR A OH  1 
ATOM   1150 N N   . ASN A 1 146 ? 146.029 140.527 109.652 1.00 96.13  ? 147 ASN A N   1 
ATOM   1151 C CA  . ASN A 1 146 ? 145.019 141.050 110.561 1.00 98.38  ? 147 ASN A CA  1 
ATOM   1152 C C   . ASN A 1 146 ? 144.073 139.957 111.055 1.00 102.93 ? 147 ASN A C   1 
ATOM   1153 O O   . ASN A 1 146 ? 144.099 138.814 110.591 1.00 105.41 ? 147 ASN A O   1 
ATOM   1154 C CB  . ASN A 1 146 ? 144.268 142.224 109.902 1.00 96.62  ? 147 ASN A CB  1 
ATOM   1155 C CG  . ASN A 1 146 ? 143.558 141.848 108.603 1.00 97.81  ? 147 ASN A CG  1 
ATOM   1156 O OD1 . ASN A 1 146 ? 143.509 140.689 108.195 1.00 107.69 ? 147 ASN A OD1 1 
ATOM   1157 N ND2 . ASN A 1 146 ? 143.021 142.859 107.931 1.00 98.01  ? 147 ASN A ND2 1 
ATOM   1158 N N   . SER A 1 147 ? 143.234 140.336 112.019 1.00 103.17 ? 148 SER A N   1 
ATOM   1159 C CA  . SER A 1 147 ? 142.340 139.422 112.717 1.00 98.94  ? 148 SER A CA  1 
ATOM   1160 C C   . SER A 1 147 ? 141.201 138.968 111.809 1.00 110.50 ? 148 SER A C   1 
ATOM   1161 O O   . SER A 1 147 ? 140.868 139.621 110.815 1.00 113.42 ? 148 SER A O   1 
ATOM   1162 C CB  . SER A 1 147 ? 141.745 140.099 113.946 1.00 100.69 ? 148 SER A CB  1 
ATOM   1163 O OG  . SER A 1 147 ? 142.749 140.419 114.881 1.00 109.77 ? 148 SER A OG  1 
ATOM   1164 N N   . HIS A 1 148 ? 140.576 137.845 112.178 1.00 116.19 ? 149 HIS A N   1 
ATOM   1165 C CA  . HIS A 1 148 ? 139.414 137.388 111.421 1.00 108.56 ? 149 HIS A CA  1 
ATOM   1166 C C   . HIS A 1 148 ? 138.534 136.505 112.305 1.00 101.01 ? 149 HIS A C   1 
ATOM   1167 O O   . HIS A 1 148 ? 138.968 136.007 113.344 1.00 102.59 ? 149 HIS A O   1 
ATOM   1168 C CB  . HIS A 1 148 ? 139.846 136.644 110.144 1.00 111.33 ? 149 HIS A CB  1 
ATOM   1169 C CG  . HIS A 1 148 ? 138.723 136.357 109.198 1.00 114.65 ? 149 HIS A CG  1 
ATOM   1170 N ND1 . HIS A 1 148 ? 137.650 137.209 109.046 1.00 112.73 ? 149 HIS A ND1 1 
ATOM   1171 C CD2 . HIS A 1 148 ? 138.496 135.314 108.367 1.00 112.11 ? 149 HIS A CD2 1 
ATOM   1172 C CE1 . HIS A 1 148 ? 136.805 136.698 108.170 1.00 106.08 ? 149 HIS A CE1 1 
ATOM   1173 N NE2 . HIS A 1 148 ? 137.302 135.554 107.733 1.00 108.29 ? 149 HIS A NE2 1 
ATOM   1174 N N   . ASN A 1 149 ? 137.272 136.356 111.897 1.00 100.42 ? 150 ASN A N   1 
ATOM   1175 C CA  . ASN A 1 149 ? 136.345 135.375 112.447 1.00 102.54 ? 150 ASN A CA  1 
ATOM   1176 C C   . ASN A 1 149 ? 136.092 134.298 111.399 1.00 105.66 ? 150 ASN A C   1 
ATOM   1177 O O   . ASN A 1 149 ? 135.822 134.613 110.237 1.00 108.44 ? 150 ASN A O   1 
ATOM   1178 C CB  . ASN A 1 149 ? 135.021 136.030 112.849 1.00 93.73  ? 150 ASN A CB  1 
ATOM   1179 C CG  . ASN A 1 149 ? 135.023 136.529 114.279 1.00 106.24 ? 150 ASN A CG  1 
ATOM   1180 O OD1 . ASN A 1 149 ? 135.963 136.288 115.035 1.00 110.89 ? 150 ASN A OD1 1 
ATOM   1181 N ND2 . ASN A 1 149 ? 133.966 137.237 114.656 1.00 103.65 ? 150 ASN A ND2 1 
ATOM   1182 N N   . VAL A 1 150 ? 136.168 133.034 111.809 1.00 101.00 ? 151 VAL A N   1 
ATOM   1183 C CA  . VAL A 1 150 ? 136.001 131.891 110.913 1.00 96.58  ? 151 VAL A CA  1 
ATOM   1184 C C   . VAL A 1 150 ? 134.779 131.101 111.360 1.00 107.12 ? 151 VAL A C   1 
ATOM   1185 O O   . VAL A 1 150 ? 134.735 130.619 112.496 1.00 114.28 ? 151 VAL A O   1 
ATOM   1186 C CB  . VAL A 1 150 ? 137.251 130.998 110.903 1.00 101.13 ? 151 VAL A CB  1 
ATOM   1187 C CG1 . VAL A 1 150 ? 137.014 129.762 110.061 1.00 105.43 ? 151 VAL A CG1 1 
ATOM   1188 C CG2 . VAL A 1 150 ? 138.442 131.776 110.380 1.00 104.27 ? 151 VAL A CG2 1 
ATOM   1189 N N   . TYR A 1 151 ? 133.808 130.941 110.464 1.00 104.51 ? 152 TYR A N   1 
ATOM   1190 C CA  . TYR A 1 151 ? 132.531 130.318 110.790 1.00 109.31 ? 152 TYR A CA  1 
ATOM   1191 C C   . TYR A 1 151 ? 132.535 128.855 110.364 1.00 112.72 ? 152 TYR A C   1 
ATOM   1192 O O   . TYR A 1 151 ? 132.931 128.532 109.242 1.00 111.11 ? 152 TYR A O   1 
ATOM   1193 C CB  . TYR A 1 151 ? 131.377 131.056 110.107 1.00 96.54  ? 152 TYR A CB  1 
ATOM   1194 C CG  . TYR A 1 151 ? 131.410 132.557 110.300 1.00 99.64  ? 152 TYR A CG  1 
ATOM   1195 C CD1 . TYR A 1 151 ? 130.879 133.142 111.442 1.00 97.44  ? 152 TYR A CD1 1 
ATOM   1196 C CD2 . TYR A 1 151 ? 131.965 133.389 109.333 1.00 98.71  ? 152 TYR A CD2 1 
ATOM   1197 C CE1 . TYR A 1 151 ? 130.908 134.513 111.619 1.00 90.61  ? 152 TYR A CE1 1 
ATOM   1198 C CE2 . TYR A 1 151 ? 131.999 134.759 109.502 1.00 88.23  ? 152 TYR A CE2 1 
ATOM   1199 C CZ  . TYR A 1 151 ? 131.468 135.313 110.645 1.00 92.78  ? 152 TYR A CZ  1 
ATOM   1200 O OH  . TYR A 1 151 ? 131.499 136.677 110.812 1.00 111.49 ? 152 TYR A OH  1 
ATOM   1201 N N   . ILE A 1 152 ? 132.076 127.975 111.254 1.00 106.76 ? 153 ILE A N   1 
ATOM   1202 C CA  . ILE A 1 152 ? 132.198 126.529 111.084 1.00 98.83  ? 153 ILE A CA  1 
ATOM   1203 C C   . ILE A 1 152 ? 130.804 125.913 111.013 1.00 104.94 ? 153 ILE A C   1 
ATOM   1204 O O   . ILE A 1 152 ? 129.960 126.184 111.874 1.00 106.65 ? 153 ILE A O   1 
ATOM   1205 C CB  . ILE A 1 152 ? 133.006 125.905 112.238 1.00 103.67 ? 153 ILE A CB  1 
ATOM   1206 C CG1 . ILE A 1 152 ? 134.406 126.517 112.313 1.00 105.36 ? 153 ILE A CG1 1 
ATOM   1207 C CG2 . ILE A 1 152 ? 133.104 124.396 112.087 1.00 111.27 ? 153 ILE A CG2 1 
ATOM   1208 C CD1 . ILE A 1 152 ? 135.240 126.294 111.076 1.00 109.61 ? 153 ILE A CD1 1 
ATOM   1209 N N   . THR A 1 153 ? 130.566 125.081 109.995 1.00 108.41 ? 154 THR A N   1 
ATOM   1210 C CA  . THR A 1 153 ? 129.357 124.266 109.928 1.00 105.99 ? 154 THR A CA  1 
ATOM   1211 C C   . THR A 1 153 ? 129.749 122.808 109.716 1.00 107.73 ? 154 THR A C   1 
ATOM   1212 O O   . THR A 1 153 ? 130.869 122.503 109.311 1.00 108.85 ? 154 THR A O   1 
ATOM   1213 C CB  . THR A 1 153 ? 128.396 124.740 108.821 1.00 100.36 ? 154 THR A CB  1 
ATOM   1214 O OG1 . THR A 1 153 ? 127.162 124.019 108.915 1.00 108.33 ? 154 THR A OG1 1 
ATOM   1215 C CG2 . THR A 1 153 ? 128.991 124.521 107.447 1.00 100.55 ? 154 THR A CG2 1 
ATOM   1216 N N   . ALA A 1 154 ? 128.823 121.901 110.012 1.00 106.44 ? 155 ALA A N   1 
ATOM   1217 C CA  . ALA A 1 154 ? 129.100 120.471 110.009 1.00 107.98 ? 155 ALA A CA  1 
ATOM   1218 C C   . ALA A 1 154 ? 128.577 119.802 108.741 1.00 110.73 ? 155 ALA A C   1 
ATOM   1219 O O   . ALA A 1 154 ? 127.806 120.386 107.976 1.00 108.12 ? 155 ALA A O   1 
ATOM   1220 C CB  . ALA A 1 154 ? 128.482 119.802 111.238 1.00 111.08 ? 155 ALA A CB  1 
ATOM   1221 N N   . ASP A 1 155 ? 129.001 118.554 108.528 1.00 119.30 ? 156 ASP A N   1 
ATOM   1222 C CA  . ASP A 1 155 ? 128.542 117.764 107.391 1.00 117.26 ? 156 ASP A CA  1 
ATOM   1223 C C   . ASP A 1 155 ? 128.565 116.289 107.763 1.00 125.27 ? 156 ASP A C   1 
ATOM   1224 O O   . ASP A 1 155 ? 129.609 115.760 108.161 1.00 128.77 ? 156 ASP A O   1 
ATOM   1225 C CB  . ASP A 1 155 ? 129.410 118.015 106.159 1.00 107.96 ? 156 ASP A CB  1 
ATOM   1226 C CG  . ASP A 1 155 ? 129.032 117.128 104.996 1.00 119.38 ? 156 ASP A CG  1 
ATOM   1227 O OD1 . ASP A 1 155 ? 127.904 117.269 104.481 1.00 128.94 ? 156 ASP A OD1 1 
ATOM   1228 O OD2 . ASP A 1 155 ? 129.858 116.284 104.599 1.00 121.08 ? 156 ASP A OD2 1 
ATOM   1229 N N   . LYS A 1 156 ? 127.416 115.629 107.608 1.00 127.54 ? 157 LYS A N   1 
ATOM   1230 C CA  . LYS A 1 156 ? 127.247 114.226 107.968 1.00 122.83 ? 157 LYS A CA  1 
ATOM   1231 C C   . LYS A 1 156 ? 127.594 113.278 106.826 1.00 129.15 ? 157 LYS A C   1 
ATOM   1232 O O   . LYS A 1 156 ? 128.037 112.151 107.082 1.00 128.52 ? 157 LYS A O   1 
ATOM   1233 C CB  . LYS A 1 156 ? 125.800 113.994 108.425 1.00 124.35 ? 157 LYS A CB  1 
ATOM   1234 C CG  . LYS A 1 156 ? 125.489 112.617 108.992 1.00 124.54 ? 157 LYS A CG  1 
ATOM   1235 C CD  . LYS A 1 156 ? 124.035 112.514 109.409 1.00 129.12 ? 157 LYS A CD  1 
ATOM   1236 C CE  . LYS A 1 156 ? 123.759 113.348 110.647 1.00 138.55 ? 157 LYS A CE  1 
ATOM   1237 N NZ  . LYS A 1 156 ? 124.458 112.808 111.846 1.00 139.14 ? 157 LYS A NZ  1 
ATOM   1238 N N   . GLN A 1 157 ? 127.416 113.722 105.575 1.00 129.60 ? 158 GLN A N   1 
ATOM   1239 C CA  . GLN A 1 157 ? 127.630 112.854 104.417 1.00 128.19 ? 158 GLN A CA  1 
ATOM   1240 C C   . GLN A 1 157 ? 129.096 112.461 104.267 1.00 135.33 ? 158 GLN A C   1 
ATOM   1241 O O   . GLN A 1 157 ? 129.410 111.292 104.014 1.00 143.03 ? 158 GLN A O   1 
ATOM   1242 C CB  . GLN A 1 157 ? 127.127 113.547 103.151 1.00 128.81 ? 158 GLN A CB  1 
ATOM   1243 C CG  . GLN A 1 157 ? 127.372 112.769 101.870 1.00 138.37 ? 158 GLN A CG  1 
ATOM   1244 C CD  . GLN A 1 157 ? 127.336 113.649 100.637 1.00 148.54 ? 158 GLN A CD  1 
ATOM   1245 O OE1 . GLN A 1 157 ? 127.156 114.863 100.731 1.00 149.01 ? 158 GLN A OE1 1 
ATOM   1246 N NE2 . GLN A 1 157 ? 127.509 113.040 99.469  1.00 152.39 ? 158 GLN A NE2 1 
ATOM   1247 N N   . LYS A 1 158 ? 130.008 113.416 104.431 1.00 128.24 ? 159 LYS A N   1 
ATOM   1248 C CA  . LYS A 1 158 ? 131.432 113.122 104.492 1.00 125.97 ? 159 LYS A CA  1 
ATOM   1249 C C   . LYS A 1 158 ? 131.936 113.011 105.924 1.00 124.25 ? 159 LYS A C   1 
ATOM   1250 O O   . LYS A 1 158 ? 133.147 112.885 106.129 1.00 124.39 ? 159 LYS A O   1 
ATOM   1251 C CB  . LYS A 1 158 ? 132.231 114.186 103.737 1.00 123.27 ? 159 LYS A CB  1 
ATOM   1252 C CG  . LYS A 1 158 ? 131.902 114.282 102.259 1.00 125.70 ? 159 LYS A CG  1 
ATOM   1253 C CD  . LYS A 1 158 ? 132.227 112.986 101.539 1.00 133.27 ? 159 LYS A CD  1 
ATOM   1254 C CE  . LYS A 1 158 ? 133.724 112.733 101.516 1.00 133.56 ? 159 LYS A CE  1 
ATOM   1255 N NZ  . LYS A 1 158 ? 134.447 113.767 100.727 1.00 137.16 ? 159 LYS A NZ  1 
ATOM   1256 N N   . ASN A 1 159 ? 131.025 113.079 106.908 1.00 123.67 ? 160 ASN A N   1 
ATOM   1257 C CA  . ASN A 1 159 ? 131.283 113.029 108.365 1.00 122.44 ? 160 ASN A CA  1 
ATOM   1258 C C   . ASN A 1 159 ? 132.349 114.034 108.825 1.00 119.52 ? 160 ASN A C   1 
ATOM   1259 O O   . ASN A 1 159 ? 132.978 113.871 109.874 1.00 123.27 ? 160 ASN A O   1 
ATOM   1260 C CB  . ASN A 1 159 ? 131.576 111.589 108.847 1.00 122.83 ? 160 ASN A CB  1 
ATOM   1261 C CG  . ASN A 1 159 ? 133.008 111.115 108.599 1.00 122.98 ? 160 ASN A CG  1 
ATOM   1262 O OD1 . ASN A 1 159 ? 133.854 111.174 109.489 1.00 130.04 ? 160 ASN A OD1 1 
ATOM   1263 N ND2 . ASN A 1 159 ? 133.263 110.583 107.410 1.00 119.60 ? 160 ASN A ND2 1 
ATOM   1264 N N   . GLY A 1 160 ? 132.490 115.138 108.094 1.00 115.09 ? 161 GLY A N   1 
ATOM   1265 C CA  . GLY A 1 160 ? 133.491 116.136 108.412 1.00 111.74 ? 161 GLY A CA  1 
ATOM   1266 C C   . GLY A 1 160 ? 132.875 117.501 108.624 1.00 111.22 ? 161 GLY A C   1 
ATOM   1267 O O   . GLY A 1 160 ? 131.713 117.602 109.031 1.00 115.12 ? 161 GLY A O   1 
ATOM   1268 N N   . ILE A 1 161 ? 133.627 118.569 108.367 1.00 106.31 ? 162 ILE A N   1 
ATOM   1269 C CA  . ILE A 1 161 ? 133.060 119.905 108.506 1.00 107.04 ? 162 ILE A CA  1 
ATOM   1270 C C   . ILE A 1 161 ? 133.355 120.739 107.267 1.00 110.25 ? 162 ILE A C   1 
ATOM   1271 O O   . ILE A 1 161 ? 134.239 120.426 106.464 1.00 110.74 ? 162 ILE A O   1 
ATOM   1272 C CB  . ILE A 1 161 ? 133.541 120.655 109.778 1.00 109.13 ? 162 ILE A CB  1 
ATOM   1273 C CG1 . ILE A 1 161 ? 135.044 120.872 109.766 1.00 108.24 ? 162 ILE A CG1 1 
ATOM   1274 C CG2 . ILE A 1 161 ? 133.090 119.956 111.063 1.00 116.59 ? 162 ILE A CG2 1 
ATOM   1275 C CD1 . ILE A 1 161 ? 135.511 121.790 110.851 1.00 110.53 ? 162 ILE A CD1 1 
ATOM   1276 N N   . LYS A 1 162 ? 132.582 121.812 107.123 1.00 112.98 ? 163 LYS A N   1 
ATOM   1277 C CA  . LYS A 1 162 ? 132.648 122.753 106.020 1.00 111.12 ? 163 LYS A CA  1 
ATOM   1278 C C   . LYS A 1 162 ? 132.821 124.149 106.599 1.00 106.17 ? 163 LYS A C   1 
ATOM   1279 O O   . LYS A 1 162 ? 132.297 124.451 107.679 1.00 107.73 ? 163 LYS A O   1 
ATOM   1280 C CB  . LYS A 1 162 ? 131.358 122.708 105.191 1.00 111.06 ? 163 LYS A CB  1 
ATOM   1281 C CG  . LYS A 1 162 ? 131.016 121.352 104.612 1.00 114.45 ? 163 LYS A CG  1 
ATOM   1282 C CD  . LYS A 1 162 ? 132.026 120.947 103.584 1.00 120.15 ? 163 LYS A CD  1 
ATOM   1283 C CE  . LYS A 1 162 ? 131.637 119.669 102.858 1.00 127.01 ? 163 LYS A CE  1 
ATOM   1284 N NZ  . LYS A 1 162 ? 131.720 118.475 103.737 1.00 133.12 ? 163 LYS A NZ  1 
ATOM   1285 N N   . ALA A 1 163 ? 133.546 125.010 105.887 1.00 102.79 ? 164 ALA A N   1 
ATOM   1286 C CA  . ALA A 1 163 ? 133.642 126.389 106.350 1.00 94.77  ? 164 ALA A CA  1 
ATOM   1287 C C   . ALA A 1 163 ? 133.855 127.343 105.187 1.00 92.65  ? 164 ALA A C   1 
ATOM   1288 O O   . ALA A 1 163 ? 134.463 126.992 104.171 1.00 101.44 ? 164 ALA A O   1 
ATOM   1289 C CB  . ALA A 1 163 ? 134.766 126.575 107.373 1.00 99.06  ? 164 ALA A CB  1 
ATOM   1290 N N   . ASN A 1 164 ? 133.353 128.565 105.364 1.00 88.81  ? 165 ASN A N   1 
ATOM   1291 C CA  . ASN A 1 164 ? 133.536 129.657 104.420 1.00 93.41  ? 165 ASN A CA  1 
ATOM   1292 C C   . ASN A 1 164 ? 133.845 130.959 105.150 1.00 94.91  ? 165 ASN A C   1 
ATOM   1293 O O   . ASN A 1 164 ? 133.172 131.315 106.122 1.00 100.49 ? 165 ASN A O   1 
ATOM   1294 C CB  . ASN A 1 164 ? 132.313 129.792 103.481 1.00 102.07 ? 165 ASN A CB  1 
ATOM   1295 C CG  . ASN A 1 164 ? 130.974 129.960 104.211 1.00 102.40 ? 165 ASN A CG  1 
ATOM   1296 O OD1 . ASN A 1 164 ? 130.884 129.956 105.434 1.00 99.18  ? 165 ASN A OD1 1 
ATOM   1297 N ND2 . ASN A 1 164 ? 129.914 130.108 103.425 1.00 107.85 ? 165 ASN A ND2 1 
ATOM   1298 N N   . PHE A 1 165 ? 134.880 131.662 104.686 1.00 96.33  ? 166 PHE A N   1 
ATOM   1299 C CA  . PHE A 1 165 ? 135.285 132.906 105.344 1.00 94.33  ? 166 PHE A CA  1 
ATOM   1300 C C   . PHE A 1 165 ? 136.085 133.760 104.369 1.00 97.11  ? 166 PHE A C   1 
ATOM   1301 O O   . PHE A 1 165 ? 136.387 133.334 103.258 1.00 97.54  ? 166 PHE A O   1 
ATOM   1302 C CB  . PHE A 1 165 ? 136.031 132.624 106.662 1.00 96.41  ? 166 PHE A CB  1 
ATOM   1303 C CG  . PHE A 1 165 ? 137.300 131.839 106.516 1.00 93.26  ? 166 PHE A CG  1 
ATOM   1304 C CD1 . PHE A 1 165 ? 137.272 130.452 106.526 1.00 92.59  ? 166 PHE A CD1 1 
ATOM   1305 C CD2 . PHE A 1 165 ? 138.523 132.476 106.476 1.00 95.17  ? 166 PHE A CD2 1 
ATOM   1306 C CE1 . PHE A 1 165 ? 138.436 129.720 106.427 1.00 91.03  ? 166 PHE A CE1 1 
ATOM   1307 C CE2 . PHE A 1 165 ? 139.691 131.750 106.391 1.00 99.90  ? 166 PHE A CE2 1 
ATOM   1308 C CZ  . PHE A 1 165 ? 139.648 130.371 106.359 1.00 102.45 ? 166 PHE A CZ  1 
ATOM   1309 N N   . LYS A 1 166 ? 136.349 135.010 104.759 1.00 97.13  ? 167 LYS A N   1 
ATOM   1310 C CA  . LYS A 1 166 ? 136.938 135.995 103.849 1.00 96.26  ? 167 LYS A CA  1 
ATOM   1311 C C   . LYS A 1 166 ? 137.965 136.848 104.575 1.00 95.97  ? 167 LYS A C   1 
ATOM   1312 O O   . LYS A 1 166 ? 137.598 137.665 105.421 1.00 98.53  ? 167 LYS A O   1 
ATOM   1313 C CB  . LYS A 1 166 ? 135.867 136.911 103.245 1.00 94.85  ? 167 LYS A CB  1 
ATOM   1314 C CG  . LYS A 1 166 ? 134.924 136.272 102.250 1.00 98.83  ? 167 LYS A CG  1 
ATOM   1315 C CD  . LYS A 1 166 ? 133.890 137.278 101.788 1.00 101.77 ? 167 LYS A CD  1 
ATOM   1316 C CE  . LYS A 1 166 ? 134.526 138.349 100.916 1.00 99.05  ? 167 LYS A CE  1 
ATOM   1317 N NZ  . LYS A 1 166 ? 135.003 137.809 99.615  1.00 96.33  ? 167 LYS A NZ  1 
ATOM   1318 N N   . ILE A 1 167 ? 139.233 136.730 104.192 1.00 93.67  ? 168 ILE A N   1 
ATOM   1319 C CA  . ILE A 1 167 ? 140.275 137.536 104.811 1.00 99.73  ? 168 ILE A CA  1 
ATOM   1320 C C   . ILE A 1 167 ? 140.536 138.766 103.953 1.00 99.46  ? 168 ILE A C   1 
ATOM   1321 O O   . ILE A 1 167 ? 140.190 138.832 102.767 1.00 98.17  ? 168 ILE A O   1 
ATOM   1322 C CB  . ILE A 1 167 ? 141.594 136.768 105.054 1.00 93.47  ? 168 ILE A CB  1 
ATOM   1323 C CG1 . ILE A 1 167 ? 142.235 136.354 103.737 1.00 91.95  ? 168 ILE A CG1 1 
ATOM   1324 C CG2 . ILE A 1 167 ? 141.348 135.550 105.930 1.00 96.81  ? 168 ILE A CG2 1 
ATOM   1325 C CD1 . ILE A 1 167 ? 143.639 135.837 103.909 1.00 97.61  ? 168 ILE A CD1 1 
ATOM   1326 N N   . ARG A 1 168 ? 141.168 139.760 104.576 1.00 99.06  ? 169 ARG A N   1 
ATOM   1327 C CA  . ARG A 1 168 ? 141.483 141.041 103.961 1.00 97.13  ? 169 ARG A CA  1 
ATOM   1328 C C   . ARG A 1 168 ? 142.981 141.292 104.064 1.00 100.01 ? 169 ARG A C   1 
ATOM   1329 O O   . ARG A 1 168 ? 143.568 141.133 105.139 1.00 101.60 ? 169 ARG A O   1 
ATOM   1330 C CB  . ARG A 1 168 ? 140.702 142.177 104.638 1.00 95.79  ? 169 ARG A CB  1 
ATOM   1331 C CG  . ARG A 1 168 ? 139.256 141.834 104.976 1.00 93.67  ? 169 ARG A CG  1 
ATOM   1332 C CD  . ARG A 1 168 ? 138.595 142.906 105.816 1.00 95.07  ? 169 ARG A CD  1 
ATOM   1333 N NE  . ARG A 1 168 ? 139.446 143.365 106.906 1.00 100.85 ? 169 ARG A NE  1 
ATOM   1334 C CZ  . ARG A 1 168 ? 139.384 142.900 108.145 1.00 98.49  ? 169 ARG A CZ  1 
ATOM   1335 N NH1 . ARG A 1 168 ? 138.534 141.945 108.482 1.00 91.53  ? 169 ARG A NH1 1 
ATOM   1336 N NH2 . ARG A 1 168 ? 140.191 143.408 109.071 1.00 103.75 ? 169 ARG A NH2 1 
ATOM   1337 N N   . HIS A 1 169 ? 143.592 141.680 102.948 1.00 98.26  ? 170 HIS A N   1 
ATOM   1338 C CA  . HIS A 1 169 ? 145.016 141.971 102.862 1.00 100.92 ? 170 HIS A CA  1 
ATOM   1339 C C   . HIS A 1 169 ? 145.219 143.462 102.642 1.00 105.08 ? 170 HIS A C   1 
ATOM   1340 O O   . HIS A 1 169 ? 144.524 144.072 101.822 1.00 111.53 ? 170 HIS A O   1 
ATOM   1341 C CB  . HIS A 1 169 ? 145.673 141.196 101.720 1.00 101.91 ? 170 HIS A CB  1 
ATOM   1342 C CG  . HIS A 1 169 ? 145.812 139.729 101.977 1.00 100.91 ? 170 HIS A CG  1 
ATOM   1343 N ND1 . HIS A 1 169 ? 145.448 138.776 101.052 1.00 102.51 ? 170 HIS A ND1 1 
ATOM   1344 C CD2 . HIS A 1 169 ? 146.298 139.053 103.044 1.00 105.26 ? 170 HIS A CD2 1 
ATOM   1345 C CE1 . HIS A 1 169 ? 145.693 137.574 101.542 1.00 108.02 ? 170 HIS A CE1 1 
ATOM   1346 N NE2 . HIS A 1 169 ? 146.211 137.715 102.749 1.00 110.89 ? 170 HIS A NE2 1 
ATOM   1347 N N   . ASN A 1 170 ? 146.179 144.034 103.363 1.00 106.54 ? 171 ASN A N   1 
ATOM   1348 C CA  . ASN A 1 170 ? 146.486 145.452 103.249 1.00 102.52 ? 171 ASN A CA  1 
ATOM   1349 C C   . ASN A 1 170 ? 147.427 145.691 102.074 1.00 109.08 ? 171 ASN A C   1 
ATOM   1350 O O   . ASN A 1 170 ? 148.430 144.988 101.916 1.00 118.16 ? 171 ASN A O   1 
ATOM   1351 C CB  . ASN A 1 170 ? 147.114 145.965 104.545 1.00 101.29 ? 171 ASN A CB  1 
ATOM   1352 C CG  . ASN A 1 170 ? 146.290 145.621 105.774 1.00 100.00 ? 171 ASN A CG  1 
ATOM   1353 O OD1 . ASN A 1 170 ? 146.836 145.329 106.836 1.00 104.54 ? 171 ASN A OD1 1 
ATOM   1354 N ND2 . ASN A 1 170 ? 144.971 145.658 105.636 1.00 96.83  ? 171 ASN A ND2 1 
ATOM   1355 N N   . ILE A 1 171 ? 147.103 146.684 101.255 1.00 104.17 ? 172 ILE A N   1 
ATOM   1356 C CA  . ILE A 1 171 ? 147.868 147.009 100.057 1.00 105.92 ? 172 ILE A CA  1 
ATOM   1357 C C   . ILE A 1 171 ? 148.706 148.249 100.350 1.00 111.12 ? 172 ILE A C   1 
ATOM   1358 O O   . ILE A 1 171 ? 148.303 149.119 101.131 1.00 116.10 ? 172 ILE A O   1 
ATOM   1359 C CB  . ILE A 1 171 ? 146.912 147.203 98.856  1.00 103.52 ? 172 ILE A CB  1 
ATOM   1360 C CG1 . ILE A 1 171 ? 145.987 145.985 98.739  1.00 106.21 ? 172 ILE A CG1 1 
ATOM   1361 C CG2 . ILE A 1 171 ? 147.669 147.394 97.541  1.00 112.39 ? 172 ILE A CG2 1 
ATOM   1362 C CD1 . ILE A 1 171 ? 145.177 145.906 97.452  1.00 114.36 ? 172 ILE A CD1 1 
ATOM   1363 N N   . GLU A 1 172 ? 149.905 148.304 99.751  1.00 110.49 ? 173 GLU A N   1 
ATOM   1364 C CA  . GLU A 1 172 ? 150.823 149.425 99.951  1.00 114.01 ? 173 GLU A CA  1 
ATOM   1365 C C   . GLU A 1 172 ? 150.234 150.740 99.447  1.00 122.62 ? 173 GLU A C   1 
ATOM   1366 O O   . GLU A 1 172 ? 150.480 151.803 100.030 1.00 123.27 ? 173 GLU A O   1 
ATOM   1367 C CB  . GLU A 1 172 ? 152.151 149.127 99.251  1.00 119.65 ? 173 GLU A CB  1 
ATOM   1368 C CG  . GLU A 1 172 ? 153.232 150.176 99.444  1.00 130.81 ? 173 GLU A CG  1 
ATOM   1369 C CD  . GLU A 1 172 ? 154.533 149.803 98.768  1.00 143.93 ? 173 GLU A CD  1 
ATOM   1370 O OE1 . GLU A 1 172 ? 154.583 148.732 98.127  1.00 144.09 ? 173 GLU A OE1 1 
ATOM   1371 O OE2 . GLU A 1 172 ? 155.505 150.580 98.875  1.00 149.87 ? 173 GLU A OE2 1 
ATOM   1372 N N   . ASP A 1 173 ? 149.451 150.686 98.366  1.00 122.38 ? 174 ASP A N   1 
ATOM   1373 C CA  . ASP A 1 173 ? 148.777 151.881 97.866  1.00 114.60 ? 174 ASP A CA  1 
ATOM   1374 C C   . ASP A 1 173 ? 147.708 152.367 98.838  1.00 114.19 ? 174 ASP A C   1 
ATOM   1375 O O   . ASP A 1 173 ? 147.493 153.576 98.980  1.00 115.32 ? 174 ASP A O   1 
ATOM   1376 C CB  . ASP A 1 173 ? 148.168 151.598 96.494  1.00 117.89 ? 174 ASP A CB  1 
ATOM   1377 C CG  . ASP A 1 173 ? 147.574 152.834 95.853  1.00 132.77 ? 174 ASP A CG  1 
ATOM   1378 O OD1 . ASP A 1 173 ? 148.347 153.696 95.385  1.00 137.52 ? 174 ASP A OD1 1 
ATOM   1379 O OD2 . ASP A 1 173 ? 146.331 152.941 95.816  1.00 133.21 ? 174 ASP A OD2 1 
ATOM   1380 N N   . GLY A 1 174 ? 147.032 151.445 99.518  1.00 111.11 ? 175 GLY A N   1 
ATOM   1381 C CA  . GLY A 1 174 ? 146.047 151.818 100.512 1.00 105.96 ? 175 GLY A CA  1 
ATOM   1382 C C   . GLY A 1 174 ? 144.802 150.958 100.481 1.00 105.67 ? 175 GLY A C   1 
ATOM   1383 O O   . GLY A 1 174 ? 144.036 150.931 101.448 1.00 106.63 ? 175 GLY A O   1 
ATOM   1384 N N   . GLY A 1 175 ? 144.595 150.242 99.381  1.00 108.92 ? 176 GLY A N   1 
ATOM   1385 C CA  . GLY A 1 175 ? 143.393 149.461 99.190  1.00 102.59 ? 176 GLY A CA  1 
ATOM   1386 C C   . GLY A 1 175 ? 143.395 148.169 99.992  1.00 107.89 ? 176 GLY A C   1 
ATOM   1387 O O   . GLY A 1 175 ? 144.261 147.902 100.827 1.00 114.74 ? 176 GLY A O   1 
ATOM   1388 N N   . VAL A 1 176 ? 142.372 147.358 99.732  1.00 103.70 ? 177 VAL A N   1 
ATOM   1389 C CA  . VAL A 1 176 ? 142.168 146.088 100.422 1.00 99.73  ? 177 VAL A CA  1 
ATOM   1390 C C   . VAL A 1 176 ? 141.981 144.999 99.374  1.00 102.33 ? 177 VAL A C   1 
ATOM   1391 O O   . VAL A 1 176 ? 141.195 145.157 98.434  1.00 113.71 ? 177 VAL A O   1 
ATOM   1392 C CB  . VAL A 1 176 ? 140.957 146.146 101.385 1.00 104.11 ? 177 VAL A CB  1 
ATOM   1393 C CG1 . VAL A 1 176 ? 140.694 144.795 102.008 1.00 92.83  ? 177 VAL A CG1 1 
ATOM   1394 C CG2 . VAL A 1 176 ? 141.183 147.167 102.492 1.00 107.09 ? 177 VAL A CG2 1 
ATOM   1395 N N   . GLN A 1 177 ? 142.722 143.903 99.520  1.00 95.34  ? 178 GLN A N   1 
ATOM   1396 C CA  . GLN A 1 177 ? 142.547 142.727 98.678  1.00 96.27  ? 178 GLN A CA  1 
ATOM   1397 C C   . GLN A 1 177 ? 141.734 141.686 99.435  1.00 100.13 ? 178 GLN A C   1 
ATOM   1398 O O   . GLN A 1 177 ? 142.113 141.279 100.535 1.00 102.57 ? 178 GLN A O   1 
ATOM   1399 C CB  . GLN A 1 177 ? 143.898 142.145 98.259  1.00 100.83 ? 178 GLN A CB  1 
ATOM   1400 C CG  . GLN A 1 177 ? 143.842 140.943 97.308  1.00 106.68 ? 178 GLN A CG  1 
ATOM   1401 C CD  . GLN A 1 177 ? 142.909 141.137 96.119  1.00 108.97 ? 178 GLN A CD  1 
ATOM   1402 O OE1 . GLN A 1 177 ? 141.716 140.829 96.181  1.00 109.23 ? 178 GLN A OE1 1 
ATOM   1403 N NE2 . GLN A 1 177 ? 143.455 141.657 95.028  1.00 111.96 ? 178 GLN A NE2 1 
ATOM   1404 N N   . LEU A 1 178 ? 140.622 141.256 98.847  1.00 98.98  ? 179 LEU A N   1 
ATOM   1405 C CA  . LEU A 1 178 ? 139.691 140.348 99.503  1.00 99.49  ? 179 LEU A CA  1 
ATOM   1406 C C   . LEU A 1 178 ? 139.923 138.924 99.017  1.00 98.56  ? 179 LEU A C   1 
ATOM   1407 O O   . LEU A 1 178 ? 140.089 138.696 97.815  1.00 100.10 ? 179 LEU A O   1 
ATOM   1408 C CB  . LEU A 1 178 ? 138.247 140.769 99.231  1.00 94.87  ? 179 LEU A CB  1 
ATOM   1409 C CG  . LEU A 1 178 ? 137.889 142.194 99.646  1.00 89.92  ? 179 LEU A CG  1 
ATOM   1410 C CD1 . LEU A 1 178 ? 136.524 142.579 99.112  1.00 97.86  ? 179 LEU A CD1 1 
ATOM   1411 C CD2 . LEU A 1 178 ? 137.926 142.315 101.155 1.00 91.76  ? 179 LEU A CD2 1 
ATOM   1412 N N   . ALA A 1 179 ? 139.936 137.970 99.949  1.00 93.58  ? 180 ALA A N   1 
ATOM   1413 C CA  . ALA A 1 179 ? 140.149 136.566 99.616  1.00 92.07  ? 180 ALA A CA  1 
ATOM   1414 C C   . ALA A 1 179 ? 139.064 135.721 100.265 1.00 93.63  ? 180 ALA A C   1 
ATOM   1415 O O   . ALA A 1 179 ? 138.917 135.734 101.490 1.00 101.44 ? 180 ALA A O   1 
ATOM   1416 C CB  . ALA A 1 179 ? 141.534 136.100 100.070 1.00 95.70  ? 180 ALA A CB  1 
ATOM   1417 N N   . ASP A 1 180 ? 138.326 134.973 99.447  1.00 94.46  ? 181 ASP A N   1 
ATOM   1418 C CA  . ASP A 1 180 ? 137.249 134.107 99.908  1.00 94.92  ? 181 ASP A CA  1 
ATOM   1419 C C   . ASP A 1 180 ? 137.731 132.663 99.943  1.00 102.30 ? 181 ASP A C   1 
ATOM   1420 O O   . ASP A 1 180 ? 138.212 132.132 98.941  1.00 108.33 ? 181 ASP A O   1 
ATOM   1421 C CB  . ASP A 1 180 ? 136.030 134.227 98.991  1.00 103.01 ? 181 ASP A CB  1 
ATOM   1422 C CG  . ASP A 1 180 ? 134.732 133.837 99.678  1.00 109.86 ? 181 ASP A CG  1 
ATOM   1423 O OD1 . ASP A 1 180 ? 134.771 133.104 100.689 1.00 106.58 ? 181 ASP A OD1 1 
ATOM   1424 O OD2 . ASP A 1 180 ? 133.663 134.269 99.202  1.00 114.88 ? 181 ASP A OD2 1 
ATOM   1425 N N   . HIS A 1 181 ? 137.592 132.024 101.099 1.00 101.00 ? 182 HIS A N   1 
ATOM   1426 C CA  . HIS A 1 181 ? 138.133 130.695 101.337 1.00 100.86 ? 182 HIS A CA  1 
ATOM   1427 C C   . HIS A 1 181 ? 136.983 129.742 101.609 1.00 103.33 ? 182 HIS A C   1 
ATOM   1428 O O   . HIS A 1 181 ? 136.131 130.021 102.467 1.00 101.77 ? 182 HIS A O   1 
ATOM   1429 C CB  . HIS A 1 181 ? 139.102 130.691 102.521 1.00 98.72  ? 182 HIS A CB  1 
ATOM   1430 C CG  . HIS A 1 181 ? 140.215 131.685 102.406 1.00 94.39  ? 182 HIS A CG  1 
ATOM   1431 N ND1 . HIS A 1 181 ? 140.986 132.054 103.483 1.00 86.81  ? 182 HIS A ND1 1 
ATOM   1432 C CD2 . HIS A 1 181 ? 140.685 132.391 101.351 1.00 98.74  ? 182 HIS A CD2 1 
ATOM   1433 C CE1 . HIS A 1 181 ? 141.883 132.940 103.097 1.00 96.98  ? 182 HIS A CE1 1 
ATOM   1434 N NE2 . HIS A 1 181 ? 141.725 133.160 101.806 1.00 97.29  ? 182 HIS A NE2 1 
ATOM   1435 N N   . TYR A 1 182 ? 136.969 128.623 100.882 1.00 101.76 ? 183 TYR A N   1 
ATOM   1436 C CA  . TYR A 1 182 ? 136.043 127.523 101.120 1.00 97.22  ? 183 TYR A CA  1 
ATOM   1437 C C   . TYR A 1 182 ? 136.870 126.302 101.495 1.00 100.73 ? 183 TYR A C   1 
ATOM   1438 O O   . TYR A 1 182 ? 137.658 125.816 100.674 1.00 106.58 ? 183 TYR A O   1 
ATOM   1439 C CB  . TYR A 1 182 ? 135.212 127.218 99.874  1.00 102.91 ? 183 TYR A CB  1 
ATOM   1440 C CG  . TYR A 1 182 ? 134.282 128.317 99.425  1.00 101.10 ? 183 TYR A CG  1 
ATOM   1441 C CD1 . TYR A 1 182 ? 133.258 128.764 100.239 1.00 94.10  ? 183 TYR A CD1 1 
ATOM   1442 C CD2 . TYR A 1 182 ? 134.435 128.908 98.177  1.00 104.99 ? 183 TYR A CD2 1 
ATOM   1443 C CE1 . TYR A 1 182 ? 132.407 129.770 99.829  1.00 103.64 ? 183 TYR A CE1 1 
ATOM   1444 C CE2 . TYR A 1 182 ? 133.591 129.915 97.756  1.00 105.16 ? 183 TYR A CE2 1 
ATOM   1445 C CZ  . TYR A 1 182 ? 132.578 130.342 98.586  1.00 111.99 ? 183 TYR A CZ  1 
ATOM   1446 O OH  . TYR A 1 182 ? 131.734 131.344 98.172  1.00 122.31 ? 183 TYR A OH  1 
ATOM   1447 N N   . GLN A 1 183 ? 136.700 125.804 102.719 1.00 98.13  ? 184 GLN A N   1 
ATOM   1448 C CA  . GLN A 1 183 ? 137.444 124.629 103.147 1.00 100.39 ? 184 GLN A CA  1 
ATOM   1449 C C   . GLN A 1 183 ? 136.509 123.473 103.465 1.00 104.41 ? 184 GLN A C   1 
ATOM   1450 O O   . GLN A 1 183 ? 135.378 123.667 103.936 1.00 108.32 ? 184 GLN A O   1 
ATOM   1451 C CB  . GLN A 1 183 ? 138.345 124.890 104.367 1.00 96.54  ? 184 GLN A CB  1 
ATOM   1452 C CG  . GLN A 1 183 ? 137.643 125.201 105.656 1.00 97.86  ? 184 GLN A CG  1 
ATOM   1453 C CD  . GLN A 1 183 ? 138.598 125.445 106.802 1.00 99.76  ? 184 GLN A CD  1 
ATOM   1454 O OE1 . GLN A 1 183 ? 139.810 125.325 106.649 1.00 99.37  ? 184 GLN A OE1 1 
ATOM   1455 N NE2 . GLN A 1 183 ? 138.055 125.783 107.963 1.00 105.93 ? 184 GLN A NE2 1 
ATOM   1456 N N   . GLN A 1 184 ? 137.020 122.274 103.197 1.00 104.35 ? 185 GLN A N   1 
ATOM   1457 C CA  . GLN A 1 184 ? 136.386 121.004 103.509 1.00 102.86 ? 185 GLN A CA  1 
ATOM   1458 C C   . GLN A 1 184 ? 137.366 120.203 104.353 1.00 105.33 ? 185 GLN A C   1 
ATOM   1459 O O   . GLN A 1 184 ? 138.499 119.954 103.922 1.00 103.00 ? 185 GLN A O   1 
ATOM   1460 C CB  . GLN A 1 184 ? 136.027 120.252 102.223 1.00 103.33 ? 185 GLN A CB  1 
ATOM   1461 C CG  . GLN A 1 184 ? 134.881 120.849 101.405 1.00 107.94 ? 185 GLN A CG  1 
ATOM   1462 C CD  . GLN A 1 184 ? 135.255 122.054 100.562 1.00 115.33 ? 185 GLN A CD  1 
ATOM   1463 O OE1 . GLN A 1 184 ? 136.426 122.328 100.325 1.00 118.41 ? 185 GLN A OE1 1 
ATOM   1464 N NE2 . GLN A 1 184 ? 134.244 122.785 100.104 1.00 118.28 ? 185 GLN A NE2 1 
ATOM   1465 N N   . ASN A 1 185 ? 136.946 119.814 105.554 1.00 106.46 ? 186 ASN A N   1 
ATOM   1466 C CA  . ASN A 1 185 ? 137.787 119.048 106.464 1.00 105.78 ? 186 ASN A CA  1 
ATOM   1467 C C   . ASN A 1 185 ? 137.203 117.651 106.587 1.00 109.34 ? 186 ASN A C   1 
ATOM   1468 O O   . ASN A 1 185 ? 136.051 117.496 107.015 1.00 114.15 ? 186 ASN A O   1 
ATOM   1469 C CB  . ASN A 1 185 ? 137.858 119.704 107.840 1.00 107.34 ? 186 ASN A CB  1 
ATOM   1470 C CG  . ASN A 1 185 ? 138.592 121.017 107.823 1.00 111.39 ? 186 ASN A CG  1 
ATOM   1471 O OD1 . ASN A 1 185 ? 139.608 121.157 107.162 1.00 114.59 ? 186 ASN A OD1 1 
ATOM   1472 N ND2 . ASN A 1 185 ? 138.079 121.993 108.562 1.00 109.26 ? 186 ASN A ND2 1 
ATOM   1473 N N   . THR A 1 186 ? 137.999 116.641 106.225 1.00 106.19 ? 187 THR A N   1 
ATOM   1474 C CA  . THR A 1 186 ? 137.554 115.256 106.278 1.00 107.35 ? 187 THR A CA  1 
ATOM   1475 C C   . THR A 1 186 ? 138.468 114.423 107.171 1.00 117.13 ? 187 THR A C   1 
ATOM   1476 O O   . THR A 1 186 ? 139.694 114.547 107.087 1.00 119.41 ? 187 THR A O   1 
ATOM   1477 C CB  . THR A 1 186 ? 137.514 114.624 104.877 1.00 108.80 ? 187 THR A CB  1 
ATOM   1478 O OG1 . THR A 1 186 ? 138.829 114.631 104.311 1.00 109.83 ? 187 THR A OG1 1 
ATOM   1479 C CG2 . THR A 1 186 ? 136.567 115.383 103.960 1.00 111.43 ? 187 THR A CG2 1 
ATOM   1480 N N   . PRO A 1 187 ? 137.912 113.565 108.027 1.00 118.24 ? 188 PRO A N   1 
ATOM   1481 C CA  . PRO A 1 187 ? 138.752 112.699 108.862 1.00 117.71 ? 188 PRO A CA  1 
ATOM   1482 C C   . PRO A 1 187 ? 139.061 111.365 108.200 1.00 118.59 ? 188 PRO A C   1 
ATOM   1483 O O   . PRO A 1 187 ? 138.199 110.719 107.598 1.00 117.34 ? 188 PRO A O   1 
ATOM   1484 C CB  . PRO A 1 187 ? 137.898 112.492 110.122 1.00 116.55 ? 188 PRO A CB  1 
ATOM   1485 C CG  . PRO A 1 187 ? 136.546 113.116 109.829 1.00 119.32 ? 188 PRO A CG  1 
ATOM   1486 C CD  . PRO A 1 187 ? 136.491 113.441 108.375 1.00 117.14 ? 188 PRO A CD  1 
ATOM   1487 N N   . ILE A 1 188 ? 140.319 110.940 108.328 1.00 119.20 ? 189 ILE A N   1 
ATOM   1488 C CA  . ILE A 1 188 ? 140.733 109.661 107.760 1.00 125.54 ? 189 ILE A CA  1 
ATOM   1489 C C   . ILE A 1 188 ? 140.670 108.518 108.766 1.00 134.13 ? 189 ILE A C   1 
ATOM   1490 O O   . ILE A 1 188 ? 140.866 107.357 108.380 1.00 134.11 ? 189 ILE A O   1 
ATOM   1491 C CB  . ILE A 1 188 ? 142.153 109.741 107.179 1.00 122.12 ? 189 ILE A CB  1 
ATOM   1492 C CG1 . ILE A 1 188 ? 143.167 110.057 108.277 1.00 120.01 ? 189 ILE A CG1 1 
ATOM   1493 C CG2 . ILE A 1 188 ? 142.214 110.777 106.081 1.00 120.01 ? 189 ILE A CG2 1 
ATOM   1494 C CD1 . ILE A 1 188 ? 144.600 109.921 107.822 1.00 129.24 ? 189 ILE A CD1 1 
ATOM   1495 N N   . GLY A 1 189 ? 140.417 108.810 110.040 1.00 138.50 ? 190 GLY A N   1 
ATOM   1496 C CA  . GLY A 1 189 ? 140.273 107.758 111.019 1.00 135.60 ? 190 GLY A CA  1 
ATOM   1497 C C   . GLY A 1 189 ? 138.929 107.063 110.934 1.00 129.45 ? 190 GLY A C   1 
ATOM   1498 O O   . GLY A 1 189 ? 137.951 107.591 110.407 1.00 131.68 ? 190 GLY A O   1 
ATOM   1499 N N   . ASP A 1 190 ? 138.889 105.843 111.467 1.00 127.23 ? 191 ASP A N   1 
ATOM   1500 C CA  . ASP A 1 190 ? 137.672 105.045 111.488 1.00 140.30 ? 191 ASP A CA  1 
ATOM   1501 C C   . ASP A 1 190 ? 137.016 105.032 112.864 1.00 135.24 ? 191 ASP A C   1 
ATOM   1502 O O   . ASP A 1 190 ? 136.070 104.271 113.092 1.00 136.58 ? 191 ASP A O   1 
ATOM   1503 C CB  . ASP A 1 190 ? 137.965 103.620 111.018 1.00 150.46 ? 191 ASP A CB  1 
ATOM   1504 C CG  . ASP A 1 190 ? 138.475 103.575 109.590 1.00 148.84 ? 191 ASP A CG  1 
ATOM   1505 O OD1 . ASP A 1 190 ? 138.460 104.628 108.920 1.00 139.97 ? 191 ASP A OD1 1 
ATOM   1506 O OD2 . ASP A 1 190 ? 138.889 102.487 109.139 1.00 155.83 ? 191 ASP A OD2 1 
ATOM   1507 N N   . GLY A 1 191 ? 137.497 105.860 113.785 1.00 125.97 ? 192 GLY A N   1 
ATOM   1508 C CA  . GLY A 1 191 ? 136.876 105.999 115.078 1.00 121.52 ? 192 GLY A CA  1 
ATOM   1509 C C   . GLY A 1 191 ? 135.751 107.012 115.038 1.00 120.27 ? 192 GLY A C   1 
ATOM   1510 O O   . GLY A 1 191 ? 135.367 107.500 113.971 1.00 122.64 ? 192 GLY A O   1 
ATOM   1511 N N   . PRO A 1 192 ? 135.197 107.351 116.200 1.00 128.03 ? 193 PRO A N   1 
ATOM   1512 C CA  . PRO A 1 192 ? 134.117 108.340 116.231 1.00 127.04 ? 193 PRO A CA  1 
ATOM   1513 C C   . PRO A 1 192 ? 134.648 109.763 116.151 1.00 124.39 ? 193 PRO A C   1 
ATOM   1514 O O   . PRO A 1 192 ? 135.670 110.108 116.750 1.00 120.06 ? 193 PRO A O   1 
ATOM   1515 C CB  . PRO A 1 192 ? 133.435 108.066 117.576 1.00 128.45 ? 193 PRO A CB  1 
ATOM   1516 C CG  . PRO A 1 192 ? 134.542 107.568 118.447 1.00 132.11 ? 193 PRO A CG  1 
ATOM   1517 C CD  . PRO A 1 192 ? 135.495 106.813 117.541 1.00 133.28 ? 193 PRO A CD  1 
ATOM   1518 N N   . VAL A 1 193 ? 133.947 110.589 115.381 1.00 126.10 ? 194 VAL A N   1 
ATOM   1519 C CA  . VAL A 1 193 ? 134.278 111.999 115.242 1.00 122.98 ? 194 VAL A CA  1 
ATOM   1520 C C   . VAL A 1 193 ? 133.112 112.821 115.769 1.00 124.35 ? 194 VAL A C   1 
ATOM   1521 O O   . VAL A 1 193 ? 131.969 112.355 115.820 1.00 128.01 ? 194 VAL A O   1 
ATOM   1522 C CB  . VAL A 1 193 ? 134.616 112.384 113.784 1.00 122.32 ? 194 VAL A CB  1 
ATOM   1523 C CG1 . VAL A 1 193 ? 135.843 111.623 113.309 1.00 118.71 ? 194 VAL A CG1 1 
ATOM   1524 C CG2 . VAL A 1 193 ? 133.434 112.112 112.867 1.00 122.55 ? 194 VAL A CG2 1 
ATOM   1525 N N   . LEU A 1 194 ? 133.409 114.050 116.178 1.00 121.22 ? 195 LEU A N   1 
ATOM   1526 C CA  . LEU A 1 194 ? 132.400 114.934 116.745 1.00 127.53 ? 195 LEU A CA  1 
ATOM   1527 C C   . LEU A 1 194 ? 131.898 115.888 115.670 1.00 131.32 ? 195 LEU A C   1 
ATOM   1528 O O   . LEU A 1 194 ? 132.686 116.628 115.072 1.00 133.04 ? 195 LEU A O   1 
ATOM   1529 C CB  . LEU A 1 194 ? 132.962 115.714 117.932 1.00 127.80 ? 195 LEU A CB  1 
ATOM   1530 C CG  . LEU A 1 194 ? 132.909 114.994 119.279 1.00 134.11 ? 195 LEU A CG  1 
ATOM   1531 C CD1 . LEU A 1 194 ? 133.872 115.630 120.272 1.00 135.98 ? 195 LEU A CD1 1 
ATOM   1532 C CD2 . LEU A 1 194 ? 131.489 114.977 119.824 1.00 123.94 ? 195 LEU A CD2 1 
ATOM   1533 N N   . LEU A 1 195 ? 130.589 115.872 115.428 1.00 125.54 ? 196 LEU A N   1 
ATOM   1534 C CA  . LEU A 1 195 ? 129.974 116.810 114.501 1.00 119.52 ? 196 LEU A CA  1 
ATOM   1535 C C   . LEU A 1 195 ? 129.379 117.957 115.305 1.00 120.14 ? 196 LEU A C   1 
ATOM   1536 O O   . LEU A 1 195 ? 128.414 117.738 116.052 1.00 126.40 ? 196 LEU A O   1 
ATOM   1537 C CB  . LEU A 1 195 ? 128.902 116.126 113.665 1.00 122.42 ? 196 LEU A CB  1 
ATOM   1538 C CG  . LEU A 1 195 ? 129.351 115.029 112.692 1.00 127.66 ? 196 LEU A CG  1 
ATOM   1539 C CD1 . LEU A 1 195 ? 129.251 113.636 113.306 1.00 126.54 ? 196 LEU A CD1 1 
ATOM   1540 C CD2 . LEU A 1 195 ? 128.553 115.106 111.399 1.00 122.16 ? 196 LEU A CD2 1 
ATOM   1541 N N   . PRO A 1 196 ? 129.906 119.174 115.196 1.00 119.30 ? 197 PRO A N   1 
ATOM   1542 C CA  . PRO A 1 196 ? 129.451 120.258 116.072 1.00 121.44 ? 197 PRO A CA  1 
ATOM   1543 C C   . PRO A 1 196 ? 128.297 121.058 115.494 1.00 122.87 ? 197 PRO A C   1 
ATOM   1544 O O   . PRO A 1 196 ? 127.847 120.797 114.374 1.00 128.77 ? 197 PRO A O   1 
ATOM   1545 C CB  . PRO A 1 196 ? 130.708 121.121 116.212 1.00 124.92 ? 197 PRO A CB  1 
ATOM   1546 C CG  . PRO A 1 196 ? 131.421 120.943 114.892 1.00 122.04 ? 197 PRO A CG  1 
ATOM   1547 C CD  . PRO A 1 196 ? 130.983 119.618 114.295 1.00 118.57 ? 197 PRO A CD  1 
ATOM   1548 N N   . ASP A 1 197 ? 127.810 122.033 116.253 1.00 114.55 ? 198 ASP A N   1 
ATOM   1549 C CA  . ASP A 1 197 ? 126.861 123.014 115.751 1.00 114.07 ? 198 ASP A CA  1 
ATOM   1550 C C   . ASP A 1 197 ? 127.609 124.227 115.209 1.00 116.53 ? 198 ASP A C   1 
ATOM   1551 O O   . ASP A 1 197 ? 128.839 124.251 115.135 1.00 126.57 ? 198 ASP A O   1 
ATOM   1552 C CB  . ASP A 1 197 ? 125.875 123.431 116.845 1.00 122.89 ? 198 ASP A CB  1 
ATOM   1553 C CG  . ASP A 1 197 ? 124.908 122.323 117.210 1.00 132.75 ? 198 ASP A CG  1 
ATOM   1554 O OD1 . ASP A 1 197 ? 124.599 121.490 116.333 1.00 132.23 ? 198 ASP A OD1 1 
ATOM   1555 O OD2 . ASP A 1 197 ? 124.453 122.286 118.373 1.00 133.81 ? 198 ASP A OD2 1 
ATOM   1556 N N   . ASN A 1 198 ? 126.844 125.244 114.820 1.00 109.78 ? 199 ASN A N   1 
ATOM   1557 C CA  . ASN A 1 198 ? 127.434 126.428 114.211 1.00 108.30 ? 199 ASN A CA  1 
ATOM   1558 C C   . ASN A 1 198 ? 128.114 127.294 115.264 1.00 110.97 ? 199 ASN A C   1 
ATOM   1559 O O   . ASN A 1 198 ? 127.525 127.613 116.300 1.00 114.25 ? 199 ASN A O   1 
ATOM   1560 C CB  . ASN A 1 198 ? 126.360 127.229 113.478 1.00 112.05 ? 199 ASN A CB  1 
ATOM   1561 C CG  . ASN A 1 198 ? 125.851 126.520 112.242 1.00 119.36 ? 199 ASN A CG  1 
ATOM   1562 O OD1 . ASN A 1 198 ? 126.203 125.369 111.985 1.00 116.47 ? 199 ASN A OD1 1 
ATOM   1563 N ND2 . ASN A 1 198 ? 125.020 127.204 111.466 1.00 123.68 ? 199 ASN A ND2 1 
ATOM   1564 N N   . HIS A 1 199 ? 129.357 127.677 114.988 1.00 107.51 ? 200 HIS A N   1 
ATOM   1565 C CA  . HIS A 1 199 ? 130.160 128.480 115.904 1.00 104.49 ? 200 HIS A CA  1 
ATOM   1566 C C   . HIS A 1 199 ? 131.227 129.200 115.085 1.00 106.06 ? 200 HIS A C   1 
ATOM   1567 O O   . HIS A 1 199 ? 131.288 129.058 113.858 1.00 105.42 ? 200 HIS A O   1 
ATOM   1568 C CB  . HIS A 1 199 ? 130.744 127.602 117.018 1.00 105.09 ? 200 HIS A CB  1 
ATOM   1569 C CG  . HIS A 1 199 ? 131.722 126.573 116.541 1.00 108.30 ? 200 HIS A CG  1 
ATOM   1570 N ND1 . HIS A 1 199 ? 131.386 125.246 116.388 1.00 115.85 ? 200 HIS A ND1 1 
ATOM   1571 C CD2 . HIS A 1 199 ? 133.034 126.667 116.220 1.00 114.49 ? 200 HIS A CD2 1 
ATOM   1572 C CE1 . HIS A 1 199 ? 132.442 124.571 115.971 1.00 118.10 ? 200 HIS A CE1 1 
ATOM   1573 N NE2 . HIS A 1 199 ? 133.455 125.410 115.861 1.00 118.78 ? 200 HIS A NE2 1 
ATOM   1574 N N   . TYR A 1 200 ? 132.068 129.988 115.756 1.00 109.52 ? 201 TYR A N   1 
ATOM   1575 C CA  . TYR A 1 200 ? 133.136 130.687 115.056 1.00 103.31 ? 201 TYR A CA  1 
ATOM   1576 C C   . TYR A 1 200 ? 134.402 130.695 115.904 1.00 103.21 ? 201 TYR A C   1 
ATOM   1577 O O   . TYR A 1 200 ? 134.386 130.439 117.112 1.00 100.67 ? 201 TYR A O   1 
ATOM   1578 C CB  . TYR A 1 200 ? 132.713 132.113 114.639 1.00 95.78  ? 201 TYR A CB  1 
ATOM   1579 C CG  . TYR A 1 200 ? 132.463 133.135 115.738 1.00 98.03  ? 201 TYR A CG  1 
ATOM   1580 C CD1 . TYR A 1 200 ? 133.507 133.867 116.301 1.00 99.20  ? 201 TYR A CD1 1 
ATOM   1581 C CD2 . TYR A 1 200 ? 131.172 133.400 116.179 1.00 99.34  ? 201 TYR A CD2 1 
ATOM   1582 C CE1 . TYR A 1 200 ? 133.276 134.802 117.289 1.00 101.53 ? 201 TYR A CE1 1 
ATOM   1583 C CE2 . TYR A 1 200 ? 130.933 134.341 117.165 1.00 95.72  ? 201 TYR A CE2 1 
ATOM   1584 C CZ  . TYR A 1 200 ? 131.988 135.035 117.715 1.00 96.79  ? 201 TYR A CZ  1 
ATOM   1585 O OH  . TYR A 1 200 ? 131.754 135.969 118.696 1.00 97.36  ? 201 TYR A OH  1 
ATOM   1586 N N   . LEU A 1 201 ? 135.510 130.975 115.228 1.00 104.66 ? 202 LEU A N   1 
ATOM   1587 C CA  . LEU A 1 201 ? 136.829 131.055 115.834 1.00 100.62 ? 202 LEU A CA  1 
ATOM   1588 C C   . LEU A 1 201 ? 137.434 132.411 115.504 1.00 102.41 ? 202 LEU A C   1 
ATOM   1589 O O   . LEU A 1 201 ? 137.564 132.767 114.329 1.00 104.98 ? 202 LEU A O   1 
ATOM   1590 C CB  . LEU A 1 201 ? 137.752 129.934 115.338 1.00 95.82  ? 202 LEU A CB  1 
ATOM   1591 C CG  . LEU A 1 201 ? 137.635 128.502 115.880 1.00 108.70 ? 202 LEU A CG  1 
ATOM   1592 C CD1 . LEU A 1 201 ? 136.404 127.760 115.366 1.00 106.51 ? 202 LEU A CD1 1 
ATOM   1593 C CD2 . LEU A 1 201 ? 138.898 127.713 115.576 1.00 113.27 ? 202 LEU A CD2 1 
ATOM   1594 N N   . SER A 1 202 ? 137.778 133.166 116.539 1.00 103.34 ? 203 SER A N   1 
ATOM   1595 C CA  . SER A 1 202 ? 138.497 134.417 116.375 1.00 102.17 ? 203 SER A CA  1 
ATOM   1596 C C   . SER A 1 202 ? 139.990 134.134 116.296 1.00 100.14 ? 203 SER A C   1 
ATOM   1597 O O   . SER A 1 202 ? 140.564 133.516 117.202 1.00 98.63  ? 203 SER A O   1 
ATOM   1598 C CB  . SER A 1 202 ? 138.194 135.364 117.535 1.00 98.35  ? 203 SER A CB  1 
ATOM   1599 O OG  . SER A 1 202 ? 136.826 135.726 117.555 1.00 95.38  ? 203 SER A OG  1 
ATOM   1600 N N   . TYR A 1 203 ? 140.609 134.583 115.207 1.00 98.88  ? 204 TYR A N   1 
ATOM   1601 C CA  . TYR A 1 203 ? 142.034 134.420 114.959 1.00 94.33  ? 204 TYR A CA  1 
ATOM   1602 C C   . TYR A 1 203 ? 142.705 135.780 115.075 1.00 97.03  ? 204 TYR A C   1 
ATOM   1603 O O   . TYR A 1 203 ? 142.303 136.736 114.395 1.00 100.91 ? 204 TYR A O   1 
ATOM   1604 C CB  . TYR A 1 203 ? 142.298 133.818 113.576 1.00 99.93  ? 204 TYR A CB  1 
ATOM   1605 C CG  . TYR A 1 203 ? 141.892 132.369 113.404 1.00 108.45 ? 204 TYR A CG  1 
ATOM   1606 C CD1 . TYR A 1 203 ? 141.621 131.561 114.495 1.00 111.32 ? 204 TYR A CD1 1 
ATOM   1607 C CD2 . TYR A 1 203 ? 141.785 131.811 112.140 1.00 116.88 ? 204 TYR A CD2 1 
ATOM   1608 C CE1 . TYR A 1 203 ? 141.250 130.247 114.325 1.00 116.76 ? 204 TYR A CE1 1 
ATOM   1609 C CE2 . TYR A 1 203 ? 141.422 130.494 111.964 1.00 122.57 ? 204 TYR A CE2 1 
ATOM   1610 C CZ  . TYR A 1 203 ? 141.154 129.720 113.064 1.00 122.51 ? 204 TYR A CZ  1 
ATOM   1611 O OH  . TYR A 1 203 ? 140.785 128.409 112.910 1.00 124.57 ? 204 TYR A OH  1 
ATOM   1612 N N   . GLN A 1 204 ? 143.724 135.851 115.933 1.00 97.74  ? 205 GLN A N   1 
ATOM   1613 C CA  . GLN A 1 204 ? 144.564 137.022 116.130 1.00 94.08  ? 205 GLN A CA  1 
ATOM   1614 C C   . GLN A 1 204 ? 145.982 136.650 115.720 1.00 99.31  ? 205 GLN A C   1 
ATOM   1615 O O   . GLN A 1 204 ? 146.488 135.596 116.115 1.00 102.57 ? 205 GLN A O   1 
ATOM   1616 C CB  . GLN A 1 204 ? 144.542 137.474 117.598 1.00 98.13  ? 205 GLN A CB  1 
ATOM   1617 C CG  . GLN A 1 204 ? 145.283 138.773 117.874 1.00 111.48 ? 205 GLN A CG  1 
ATOM   1618 C CD  . GLN A 1 204 ? 144.590 139.962 117.254 1.00 118.14 ? 205 GLN A CD  1 
ATOM   1619 O OE1 . GLN A 1 204 ? 143.367 140.072 117.313 1.00 121.66 ? 205 GLN A OE1 1 
ATOM   1620 N NE2 . GLN A 1 204 ? 145.354 140.834 116.609 1.00 118.05 ? 205 GLN A NE2 1 
ATOM   1621 N N   . SER A 1 205 ? 146.628 137.504 114.930 1.00 97.74  ? 206 SER A N   1 
ATOM   1622 C CA  . SER A 1 205 ? 147.896 137.140 114.314 1.00 102.06 ? 206 SER A CA  1 
ATOM   1623 C C   . SER A 1 205 ? 148.959 138.201 114.564 1.00 110.81 ? 206 SER A C   1 
ATOM   1624 O O   . SER A 1 205 ? 148.661 139.371 114.815 1.00 115.83 ? 206 SER A O   1 
ATOM   1625 C CB  . SER A 1 205 ? 147.736 136.923 112.807 1.00 99.97  ? 206 SER A CB  1 
ATOM   1626 O OG  . SER A 1 205 ? 146.829 135.870 112.540 1.00 103.79 ? 206 SER A OG  1 
ATOM   1627 N N   . LYS A 1 206 ? 150.214 137.761 114.488 1.00 111.37 ? 207 LYS A N   1 
ATOM   1628 C CA  . LYS A 1 206 ? 151.373 138.641 114.609 1.00 108.20 ? 207 LYS A CA  1 
ATOM   1629 C C   . LYS A 1 206 ? 152.464 138.141 113.675 1.00 110.24 ? 207 LYS A C   1 
ATOM   1630 O O   . LYS A 1 206 ? 152.840 136.965 113.735 1.00 114.66 ? 207 LYS A O   1 
ATOM   1631 C CB  . LYS A 1 206 ? 151.883 138.692 116.051 1.00 109.50 ? 207 LYS A CB  1 
ATOM   1632 C CG  . LYS A 1 206 ? 153.109 139.571 116.246 1.00 112.26 ? 207 LYS A CG  1 
ATOM   1633 C CD  . LYS A 1 206 ? 152.785 141.035 116.027 1.00 119.37 ? 207 LYS A CD  1 
ATOM   1634 C CE  . LYS A 1 206 ? 153.970 141.921 116.368 1.00 124.79 ? 207 LYS A CE  1 
ATOM   1635 N NZ  . LYS A 1 206 ? 155.108 141.707 115.431 1.00 124.61 ? 207 LYS A NZ  1 
ATOM   1636 N N   . LEU A 1 207 ? 152.970 139.030 112.825 1.00 110.93 ? 208 LEU A N   1 
ATOM   1637 C CA  . LEU A 1 207 ? 154.056 138.710 111.910 1.00 113.15 ? 208 LEU A CA  1 
ATOM   1638 C C   . LEU A 1 207 ? 155.359 139.286 112.443 1.00 122.44 ? 208 LEU A C   1 
ATOM   1639 O O   . LEU A 1 207 ? 155.384 140.395 112.985 1.00 119.85 ? 208 LEU A O   1 
ATOM   1640 C CB  . LEU A 1 207 ? 153.796 139.266 110.508 1.00 101.98 ? 208 LEU A CB  1 
ATOM   1641 C CG  . LEU A 1 207 ? 152.483 138.941 109.797 1.00 103.15 ? 208 LEU A CG  1 
ATOM   1642 C CD1 . LEU A 1 207 ? 152.561 139.371 108.345 1.00 110.33 ? 208 LEU A CD1 1 
ATOM   1643 C CD2 . LEU A 1 207 ? 152.130 137.486 109.899 1.00 103.94 ? 208 LEU A CD2 1 
ATOM   1644 N N   . SER A 1 208 ? 156.443 138.531 112.287 1.00 124.41 ? 209 SER A N   1 
ATOM   1645 C CA  . SER A 1 208 ? 157.741 138.992 112.757 1.00 121.98 ? 209 SER A CA  1 
ATOM   1646 C C   . SER A 1 208 ? 158.835 138.429 111.862 1.00 121.09 ? 209 SER A C   1 
ATOM   1647 O O   . SER A 1 208 ? 158.621 137.486 111.097 1.00 122.06 ? 209 SER A O   1 
ATOM   1648 C CB  . SER A 1 208 ? 157.977 138.598 114.218 1.00 123.95 ? 209 SER A CB  1 
ATOM   1649 O OG  . SER A 1 208 ? 157.161 139.361 115.088 1.00 121.17 ? 209 SER A OG  1 
ATOM   1650 N N   . LYS A 1 209 ? 160.017 139.031 111.964 1.00 120.65 ? 210 LYS A N   1 
ATOM   1651 C CA  . LYS A 1 209 ? 161.190 138.597 111.222 1.00 126.21 ? 210 LYS A CA  1 
ATOM   1652 C C   . LYS A 1 209 ? 162.375 138.464 112.167 1.00 125.82 ? 210 LYS A C   1 
ATOM   1653 O O   . LYS A 1 209 ? 162.588 139.314 113.035 1.00 122.46 ? 210 LYS A O   1 
ATOM   1654 C CB  . LYS A 1 209 ? 161.532 139.574 110.091 1.00 129.35 ? 210 LYS A CB  1 
ATOM   1655 C CG  . LYS A 1 209 ? 160.555 139.551 108.927 1.00 124.85 ? 210 LYS A CG  1 
ATOM   1656 C CD  . LYS A 1 209 ? 161.064 140.396 107.771 1.00 121.39 ? 210 LYS A CD  1 
ATOM   1657 C CE  . LYS A 1 209 ? 161.473 139.533 106.590 1.00 112.63 ? 210 LYS A CE  1 
ATOM   1658 N NZ  . LYS A 1 209 ? 160.369 138.649 106.133 1.00 112.07 ? 210 LYS A NZ  1 
ATOM   1659 N N   . ASP A 1 210 ? 163.132 137.386 111.992 1.00 127.78 ? 211 ASP A N   1 
ATOM   1660 C CA  . ASP A 1 210 ? 164.317 137.152 112.803 1.00 130.76 ? 211 ASP A CA  1 
ATOM   1661 C C   . ASP A 1 210 ? 165.420 138.141 112.425 1.00 139.28 ? 211 ASP A C   1 
ATOM   1662 O O   . ASP A 1 210 ? 165.578 138.474 111.246 1.00 137.77 ? 211 ASP A O   1 
ATOM   1663 C CB  . ASP A 1 210 ? 164.809 135.717 112.613 1.00 128.00 ? 211 ASP A CB  1 
ATOM   1664 C CG  . ASP A 1 210 ? 165.809 135.297 113.665 1.00 129.98 ? 211 ASP A CG  1 
ATOM   1665 O OD1 . ASP A 1 210 ? 165.432 135.239 114.853 1.00 130.55 ? 211 ASP A OD1 1 
ATOM   1666 O OD2 . ASP A 1 210 ? 166.973 135.025 113.305 1.00 134.18 ? 211 ASP A OD2 1 
ATOM   1667 N N   . PRO A 1 211 ? 166.188 138.639 113.401 1.00 138.89 ? 212 PRO A N   1 
ATOM   1668 C CA  . PRO A 1 211 ? 167.263 139.585 113.056 1.00 133.52 ? 212 PRO A CA  1 
ATOM   1669 C C   . PRO A 1 211 ? 168.470 138.922 112.418 1.00 135.19 ? 212 PRO A C   1 
ATOM   1670 O O   . PRO A 1 211 ? 169.161 139.556 111.611 1.00 136.35 ? 212 PRO A O   1 
ATOM   1671 C CB  . PRO A 1 211 ? 167.617 140.220 114.409 1.00 130.37 ? 212 PRO A CB  1 
ATOM   1672 C CG  . PRO A 1 211 ? 166.454 139.921 115.302 1.00 133.13 ? 212 PRO A CG  1 
ATOM   1673 C CD  . PRO A 1 211 ? 165.950 138.593 114.852 1.00 131.33 ? 212 PRO A CD  1 
ATOM   1674 N N   . ASN A 1 212 ? 168.747 137.664 112.754 1.00 136.81 ? 213 ASN A N   1 
ATOM   1675 C CA  . ASN A 1 212 ? 169.960 136.992 112.307 1.00 137.64 ? 213 ASN A CA  1 
ATOM   1676 C C   . ASN A 1 212 ? 169.748 136.145 111.059 1.00 133.70 ? 213 ASN A C   1 
ATOM   1677 O O   . ASN A 1 212 ? 170.697 135.939 110.295 1.00 135.29 ? 213 ASN A O   1 
ATOM   1678 C CB  . ASN A 1 212 ? 170.510 136.109 113.437 1.00 145.81 ? 213 ASN A CB  1 
ATOM   1679 C CG  . ASN A 1 212 ? 171.915 135.596 113.162 1.00 150.58 ? 213 ASN A CG  1 
ATOM   1680 O OD1 . ASN A 1 212 ? 172.656 136.167 112.362 1.00 150.02 ? 213 ASN A OD1 1 
ATOM   1681 N ND2 . ASN A 1 212 ? 172.285 134.509 113.829 1.00 150.19 ? 213 ASN A ND2 1 
ATOM   1682 N N   . GLU A 1 213 ? 168.528 135.665 110.825 1.00 130.58 ? 214 GLU A N   1 
ATOM   1683 C CA  . GLU A 1 213 ? 168.260 134.810 109.675 1.00 136.72 ? 214 GLU A CA  1 
ATOM   1684 C C   . GLU A 1 213 ? 168.287 135.628 108.388 1.00 140.85 ? 214 GLU A C   1 
ATOM   1685 O O   . GLU A 1 213 ? 167.633 136.670 108.285 1.00 138.14 ? 214 GLU A O   1 
ATOM   1686 C CB  . GLU A 1 213 ? 166.906 134.118 109.841 1.00 137.75 ? 214 GLU A CB  1 
ATOM   1687 C CG  . GLU A 1 213 ? 166.532 133.145 108.725 1.00 140.85 ? 214 GLU A CG  1 
ATOM   1688 C CD  . GLU A 1 213 ? 167.430 131.918 108.663 1.00 143.61 ? 214 GLU A CD  1 
ATOM   1689 O OE1 . GLU A 1 213 ? 168.002 131.529 109.704 1.00 149.13 ? 214 GLU A OE1 1 
ATOM   1690 O OE2 . GLU A 1 213 ? 167.561 131.336 107.566 1.00 138.20 ? 214 GLU A OE2 1 
ATOM   1691 N N   . LYS A 1 214 ? 169.049 135.150 107.403 1.00 139.58 ? 215 LYS A N   1 
ATOM   1692 C CA  . LYS A 1 214 ? 169.264 135.889 106.164 1.00 137.88 ? 215 LYS A CA  1 
ATOM   1693 C C   . LYS A 1 214 ? 168.350 135.424 105.038 1.00 136.95 ? 215 LYS A C   1 
ATOM   1694 O O   . LYS A 1 214 ? 167.785 136.256 104.320 1.00 141.01 ? 215 LYS A O   1 
ATOM   1695 C CB  . LYS A 1 214 ? 170.725 135.762 105.726 1.00 138.84 ? 215 LYS A CB  1 
ATOM   1696 C CG  . LYS A 1 214 ? 171.729 136.304 106.729 1.00 137.75 ? 215 LYS A CG  1 
ATOM   1697 C CD  . LYS A 1 214 ? 171.592 137.807 106.893 1.00 136.40 ? 215 LYS A CD  1 
ATOM   1698 C CE  . LYS A 1 214 ? 172.177 138.274 108.214 1.00 138.57 ? 215 LYS A CE  1 
ATOM   1699 N NZ  . LYS A 1 214 ? 171.131 138.460 109.255 1.00 139.78 ? 215 LYS A NZ  1 
ATOM   1700 N N   . ARG A 1 215 ? 168.210 134.112 104.863 1.00 132.88 ? 216 ARG A N   1 
ATOM   1701 C CA  . ARG A 1 215 ? 167.345 133.556 103.832 1.00 134.58 ? 216 ARG A CA  1 
ATOM   1702 C C   . ARG A 1 215 ? 165.880 133.828 104.189 1.00 137.49 ? 216 ARG A C   1 
ATOM   1703 O O   . ARG A 1 215 ? 165.532 134.018 105.359 1.00 138.01 ? 216 ARG A O   1 
ATOM   1704 C CB  . ARG A 1 215 ? 167.660 132.063 103.667 1.00 135.26 ? 216 ARG A CB  1 
ATOM   1705 C CG  . ARG A 1 215 ? 166.954 131.314 102.542 1.00 140.15 ? 216 ARG A CG  1 
ATOM   1706 C CD  . ARG A 1 215 ? 167.467 129.885 102.418 1.00 143.17 ? 216 ARG A CD  1 
ATOM   1707 N NE  . ARG A 1 215 ? 167.205 129.072 103.599 1.00 137.75 ? 216 ARG A NE  1 
ATOM   1708 C CZ  . ARG A 1 215 ? 168.152 128.602 104.399 1.00 143.09 ? 216 ARG A CZ  1 
ATOM   1709 N NH1 . ARG A 1 215 ? 169.431 128.860 104.180 1.00 149.45 ? 216 ARG A NH1 1 
ATOM   1710 N NH2 . ARG A 1 215 ? 167.810 127.854 105.443 1.00 140.67 ? 216 ARG A NH2 1 
ATOM   1711 N N   . ASP A 1 216 ? 165.033 133.886 103.148 1.00 134.68 ? 217 ASP A N   1 
ATOM   1712 C CA  . ASP A 1 216 ? 163.671 134.418 103.232 1.00 130.41 ? 217 ASP A CA  1 
ATOM   1713 C C   . ASP A 1 216 ? 162.817 133.631 104.219 1.00 125.97 ? 217 ASP A C   1 
ATOM   1714 O O   . ASP A 1 216 ? 162.539 132.446 104.016 1.00 124.36 ? 217 ASP A O   1 
ATOM   1715 C CB  . ASP A 1 216 ? 163.030 134.403 101.843 1.00 134.77 ? 217 ASP A CB  1 
ATOM   1716 C CG  . ASP A 1 216 ? 161.961 135.474 101.672 1.00 141.35 ? 217 ASP A CG  1 
ATOM   1717 O OD1 . ASP A 1 216 ? 161.244 135.786 102.646 1.00 140.55 ? 217 ASP A OD1 1 
ATOM   1718 O OD2 . ASP A 1 216 ? 161.838 136.009 100.551 1.00 140.13 ? 217 ASP A OD2 1 
ATOM   1719 N N   . HIS A 1 217 ? 162.402 134.311 105.285 1.00 128.48 ? 218 HIS A N   1 
ATOM   1720 C CA  . HIS A 1 217 ? 161.819 133.686 106.461 1.00 128.98 ? 218 HIS A CA  1 
ATOM   1721 C C   . HIS A 1 217 ? 160.651 134.530 106.950 1.00 128.48 ? 218 HIS A C   1 
ATOM   1722 O O   . HIS A 1 217 ? 160.441 135.661 106.499 1.00 131.41 ? 218 HIS A O   1 
ATOM   1723 C CB  . HIS A 1 217 ? 162.860 133.511 107.574 1.00 132.00 ? 218 HIS A CB  1 
ATOM   1724 C CG  . HIS A 1 217 ? 163.427 134.801 108.089 1.00 132.68 ? 218 HIS A CG  1 
ATOM   1725 N ND1 . HIS A 1 217 ? 164.095 135.700 107.285 1.00 132.16 ? 218 HIS A ND1 1 
ATOM   1726 C CD2 . HIS A 1 217 ? 163.416 135.345 109.328 1.00 134.30 ? 218 HIS A CD2 1 
ATOM   1727 C CE1 . HIS A 1 217 ? 164.475 136.739 108.007 1.00 134.11 ? 218 HIS A CE1 1 
ATOM   1728 N NE2 . HIS A 1 217 ? 164.076 136.547 109.250 1.00 133.43 ? 218 HIS A NE2 1 
ATOM   1729 N N   . MET A 1 218 ? 159.903 133.977 107.904 1.00 122.75 ? 219 MET A N   1 
ATOM   1730 C CA  . MET A 1 218 ? 158.686 134.586 108.421 1.00 123.33 ? 219 MET A CA  1 
ATOM   1731 C C   . MET A 1 218 ? 158.314 133.905 109.730 1.00 122.30 ? 219 MET A C   1 
ATOM   1732 O O   . MET A 1 218 ? 158.404 132.680 109.841 1.00 123.25 ? 219 MET A O   1 
ATOM   1733 C CB  . MET A 1 218 ? 157.546 134.470 107.398 1.00 124.12 ? 219 MET A CB  1 
ATOM   1734 C CG  . MET A 1 218 ? 156.249 135.141 107.792 1.00 122.43 ? 219 MET A CG  1 
ATOM   1735 S SD  . MET A 1 218 ? 154.877 134.338 106.949 1.00 131.93 ? 219 MET A SD  1 
ATOM   1736 C CE  . MET A 1 218 ? 155.101 132.649 107.489 1.00 116.03 ? 219 MET A CE  1 
ATOM   1737 N N   . VAL A 1 219 ? 157.906 134.703 110.714 1.00 122.50 ? 220 VAL A N   1 
ATOM   1738 C CA  . VAL A 1 219 ? 157.577 134.220 112.051 1.00 116.24 ? 220 VAL A CA  1 
ATOM   1739 C C   . VAL A 1 219 ? 156.111 134.527 112.322 1.00 113.44 ? 220 VAL A C   1 
ATOM   1740 O O   . VAL A 1 219 ? 155.699 135.693 112.273 1.00 116.84 ? 220 VAL A O   1 
ATOM   1741 C CB  . VAL A 1 219 ? 158.476 134.859 113.121 1.00 122.43 ? 220 VAL A CB  1 
ATOM   1742 C CG1 . VAL A 1 219 ? 158.059 134.404 114.510 1.00 124.91 ? 220 VAL A CG1 1 
ATOM   1743 C CG2 . VAL A 1 219 ? 159.936 134.529 112.860 1.00 123.56 ? 220 VAL A CG2 1 
ATOM   1744 N N   . LEU A 1 220 ? 155.336 133.486 112.628 1.00 108.96 ? 221 LEU A N   1 
ATOM   1745 C CA  . LEU A 1 220 ? 153.904 133.576 112.887 1.00 111.27 ? 221 LEU A CA  1 
ATOM   1746 C C   . LEU A 1 220 ? 153.643 133.368 114.369 1.00 111.47 ? 221 LEU A C   1 
ATOM   1747 O O   . LEU A 1 220 ? 154.063 132.353 114.938 1.00 116.34 ? 221 LEU A O   1 
ATOM   1748 C CB  . LEU A 1 220 ? 153.126 132.526 112.090 1.00 112.82 ? 221 LEU A CB  1 
ATOM   1749 C CG  . LEU A 1 220 ? 153.060 132.615 110.571 1.00 117.96 ? 221 LEU A CG  1 
ATOM   1750 C CD1 . LEU A 1 220 ? 152.376 131.398 109.990 1.00 118.74 ? 221 LEU A CD1 1 
ATOM   1751 C CD2 . LEU A 1 220 ? 152.305 133.844 110.173 1.00 113.66 ? 221 LEU A CD2 1 
ATOM   1752 N N   . LEU A 1 221 ? 152.934 134.312 114.979 1.00 105.50 ? 222 LEU A N   1 
ATOM   1753 C CA  . LEU A 1 221 ? 152.365 134.152 116.308 1.00 103.19 ? 222 LEU A CA  1 
ATOM   1754 C C   . LEU A 1 221 ? 150.850 134.155 116.163 1.00 105.23 ? 222 LEU A C   1 
ATOM   1755 O O   . LEU A 1 221 ? 150.281 135.096 115.602 1.00 108.81 ? 222 LEU A O   1 
ATOM   1756 C CB  . LEU A 1 221 ? 152.854 135.269 117.238 1.00 102.54 ? 222 LEU A CB  1 
ATOM   1757 C CG  . LEU A 1 221 ? 152.582 135.316 118.745 1.00 97.75  ? 222 LEU A CG  1 
ATOM   1758 C CD1 . LEU A 1 221 ? 153.695 136.088 119.418 1.00 97.72  ? 222 LEU A CD1 1 
ATOM   1759 C CD2 . LEU A 1 221 ? 151.268 136.009 119.051 1.00 96.26  ? 222 LEU A CD2 1 
ATOM   1760 N N   . GLU A 1 222 ? 150.201 133.103 116.658 1.00 105.08 ? 223 GLU A N   1 
ATOM   1761 C CA  . GLU A 1 222 ? 148.770 132.926 116.451 1.00 102.85 ? 223 GLU A CA  1 
ATOM   1762 C C   . GLU A 1 222 ? 148.068 132.698 117.779 1.00 103.72 ? 223 GLU A C   1 
ATOM   1763 O O   . GLU A 1 222 ? 148.504 131.865 118.581 1.00 109.07 ? 223 GLU A O   1 
ATOM   1764 C CB  . GLU A 1 222 ? 148.492 131.747 115.510 1.00 109.19 ? 223 GLU A CB  1 
ATOM   1765 C CG  . GLU A 1 222 ? 148.964 131.947 114.076 1.00 113.53 ? 223 GLU A CG  1 
ATOM   1766 C CD  . GLU A 1 222 ? 148.191 133.025 113.338 1.00 114.91 ? 223 GLU A CD  1 
ATOM   1767 O OE1 . GLU A 1 222 ? 146.988 133.203 113.622 1.00 111.42 ? 223 GLU A OE1 1 
ATOM   1768 O OE2 . GLU A 1 222 ? 148.789 133.693 112.468 1.00 118.78 ? 223 GLU A OE2 1 
ATOM   1769 N N   . PHE A 1 223 ? 146.980 133.438 117.995 1.00 98.58  ? 224 PHE A N   1 
ATOM   1770 C CA  . PHE A 1 223 ? 146.058 133.233 119.105 1.00 100.17 ? 224 PHE A CA  1 
ATOM   1771 C C   . PHE A 1 223 ? 144.692 132.861 118.550 1.00 94.89  ? 224 PHE A C   1 
ATOM   1772 O O   . PHE A 1 223 ? 144.182 133.527 117.642 1.00 99.11  ? 224 PHE A O   1 
ATOM   1773 C CB  . PHE A 1 223 ? 145.939 134.483 119.982 1.00 108.95 ? 224 PHE A CB  1 
ATOM   1774 C CG  . PHE A 1 223 ? 146.971 134.570 121.066 1.00 107.47 ? 224 PHE A CG  1 
ATOM   1775 C CD1 . PHE A 1 223 ? 148.314 134.701 120.763 1.00 106.55 ? 224 PHE A CD1 1 
ATOM   1776 C CD2 . PHE A 1 223 ? 146.589 134.517 122.397 1.00 114.38 ? 224 PHE A CD2 1 
ATOM   1777 C CE1 . PHE A 1 223 ? 149.259 134.780 121.770 1.00 115.25 ? 224 PHE A CE1 1 
ATOM   1778 C CE2 . PHE A 1 223 ? 147.528 134.595 123.407 1.00 126.03 ? 224 PHE A CE2 1 
ATOM   1779 C CZ  . PHE A 1 223 ? 148.865 134.727 123.091 1.00 124.71 ? 224 PHE A CZ  1 
ATOM   1780 N N   . VAL A 1 224 ? 144.104 131.802 119.097 1.00 100.64 ? 225 VAL A N   1 
ATOM   1781 C CA  . VAL A 1 224 ? 142.825 131.270 118.643 1.00 102.06 ? 225 VAL A CA  1 
ATOM   1782 C C   . VAL A 1 224 ? 141.865 131.252 119.824 1.00 104.69 ? 225 VAL A C   1 
ATOM   1783 O O   . VAL A 1 224 ? 142.203 130.733 120.893 1.00 112.54 ? 225 VAL A O   1 
ATOM   1784 C CB  . VAL A 1 224 ? 142.982 129.857 118.052 1.00 110.34 ? 225 VAL A CB  1 
ATOM   1785 C CG1 . VAL A 1 224 ? 141.632 129.278 117.697 1.00 111.26 ? 225 VAL A CG1 1 
ATOM   1786 C CG2 . VAL A 1 224 ? 143.893 129.879 116.833 1.00 106.54 ? 225 VAL A CG2 1 
ATOM   1787 N N   . THR A 1 225 ? 140.674 131.818 119.633 1.00 103.79 ? 226 THR A N   1 
ATOM   1788 C CA  . THR A 1 225 ? 139.621 131.743 120.637 1.00 100.92 ? 226 THR A CA  1 
ATOM   1789 C C   . THR A 1 225 ? 138.368 131.200 119.963 1.00 99.77  ? 226 THR A C   1 
ATOM   1790 O O   . THR A 1 225 ? 138.066 131.556 118.827 1.00 107.24 ? 226 THR A O   1 
ATOM   1791 C CB  . THR A 1 225 ? 139.373 133.126 121.273 1.00 106.13 ? 226 THR A CB  1 
ATOM   1792 O OG1 . THR A 1 225 ? 140.589 133.600 121.864 1.00 107.20 ? 226 THR A OG1 1 
ATOM   1793 C CG2 . THR A 1 225 ? 138.309 133.064 122.362 1.00 108.77 ? 226 THR A CG2 1 
ATOM   1794 N N   . ALA A 1 226 ? 137.653 130.310 120.643 1.00 95.45  ? 227 ALA A N   1 
ATOM   1795 C CA  . ALA A 1 226 ? 136.448 129.708 120.088 1.00 104.67 ? 227 ALA A CA  1 
ATOM   1796 C C   . ALA A 1 226 ? 135.217 130.221 120.820 1.00 109.36 ? 227 ALA A C   1 
ATOM   1797 O O   . ALA A 1 226 ? 135.190 130.256 122.054 1.00 113.75 ? 227 ALA A O   1 
ATOM   1798 C CB  . ALA A 1 226 ? 136.504 128.183 120.172 1.00 117.05 ? 227 ALA A CB  1 
ATOM   1799 N N   . ALA A 1 227 ? 134.196 130.611 120.059 1.00 109.35 ? 228 ALA A N   1 
ATOM   1800 C CA  . ALA A 1 227 ? 132.948 131.108 120.630 1.00 107.95 ? 228 ALA A CA  1 
ATOM   1801 C C   . ALA A 1 227 ? 131.835 130.861 119.619 1.00 107.29 ? 228 ALA A C   1 
ATOM   1802 O O   . ALA A 1 227 ? 132.006 130.107 118.657 1.00 114.92 ? 228 ALA A O   1 
ATOM   1803 C CB  . ALA A 1 227 ? 133.065 132.589 121.003 1.00 108.75 ? 228 ALA A CB  1 
ATOM   1804 N N   . GLY A 1 228 ? 130.688 131.496 119.828 1.00 108.54 ? 229 GLY A N   1 
ATOM   1805 C CA  . GLY A 1 228 ? 129.642 131.429 118.828 1.00 118.41 ? 229 GLY A CA  1 
ATOM   1806 C C   . GLY A 1 228 ? 128.243 131.204 119.356 1.00 132.04 ? 229 GLY A C   1 
ATOM   1807 O O   . GLY A 1 228 ? 127.276 131.712 118.781 1.00 133.14 ? 229 GLY A O   1 
ATOM   1808 N N   . ILE A 1 229 ? 128.112 130.452 120.442 1.00 131.11 ? 230 ILE A N   1 
ATOM   1809 C CA  . ILE A 1 229 ? 126.808 130.180 121.025 1.00 133.78 ? 230 ILE A CA  1 
ATOM   1810 C C   . ILE A 1 229 ? 126.751 130.772 122.427 1.00 135.73 ? 230 ILE A C   1 
ATOM   1811 O O   . ILE A 1 229 ? 127.755 130.878 123.139 1.00 133.86 ? 230 ILE A O   1 
ATOM   1812 C CB  . ILE A 1 229 ? 126.469 128.673 121.027 1.00 131.28 ? 230 ILE A CB  1 
ATOM   1813 C CG1 . ILE A 1 229 ? 127.469 127.881 121.863 1.00 130.09 ? 230 ILE A CG1 1 
ATOM   1814 C CG2 . ILE A 1 229 ? 126.416 128.134 119.604 1.00 129.95 ? 230 ILE A CG2 1 
ATOM   1815 C CD1 . ILE A 1 229 ? 127.060 126.445 122.074 1.00 136.28 ? 230 ILE A CD1 1 
ATOM   1816 N N   . THR A 1 230 ? 125.546 131.185 122.810 1.00 140.02 ? 231 THR A N   1 
ATOM   1817 C CA  . THR A 1 230 ? 125.314 131.939 124.033 1.00 141.88 ? 231 THR A CA  1 
ATOM   1818 C C   . THR A 1 230 ? 125.415 131.007 125.237 1.00 137.13 ? 231 THR A C   1 
ATOM   1819 O O   . THR A 1 230 ? 124.901 129.885 125.199 1.00 135.95 ? 231 THR A O   1 
ATOM   1820 C CB  . THR A 1 230 ? 123.938 132.613 123.966 1.00 145.99 ? 231 THR A CB  1 
ATOM   1821 O OG1 . THR A 1 230 ? 123.923 133.547 122.879 1.00 147.81 ? 231 THR A OG1 1 
ATOM   1822 C CG2 . THR A 1 230 ? 123.611 133.371 125.247 1.00 140.69 ? 231 THR A CG2 1 
ATOM   1823 N N   . THR A 1 231 ? 126.114 131.462 126.278 1.00 131.93 ? 232 THR A N   1 
ATOM   1824 C CA  . THR A 1 231 ? 126.171 130.722 127.531 1.00 137.10 ? 232 THR A CA  1 
ATOM   1825 C C   . THR A 1 231 ? 124.776 130.636 128.153 1.00 144.01 ? 232 THR A C   1 
ATOM   1826 O O   . THR A 1 231 ? 123.981 131.577 128.028 1.00 144.75 ? 232 THR A O   1 
ATOM   1827 C CB  . THR A 1 231 ? 127.173 131.382 128.491 1.00 133.17 ? 232 THR A CB  1 
ATOM   1828 O OG1 . THR A 1 231 ? 127.190 130.689 129.746 1.00 130.95 ? 232 THR A OG1 1 
ATOM   1829 C CG2 . THR A 1 231 ? 126.871 132.866 128.709 1.00 137.19 ? 232 THR A CG2 1 
ATOM   1830 N N   . PRO A 1 232 ? 124.418 129.502 128.766 1.00 144.00 ? 233 PRO A N   1 
ATOM   1831 C CA  . PRO A 1 232 ? 123.028 129.329 129.228 1.00 145.48 ? 233 PRO A CA  1 
ATOM   1832 C C   . PRO A 1 232 ? 122.640 130.212 130.402 1.00 149.62 ? 233 PRO A C   1 
ATOM   1833 O O   . PRO A 1 232 ? 121.444 130.436 130.624 1.00 151.38 ? 233 PRO A O   1 
ATOM   1834 C CB  . PRO A 1 232 ? 122.967 127.841 129.606 1.00 144.52 ? 233 PRO A CB  1 
ATOM   1835 C CG  . PRO A 1 232 ? 124.134 127.210 128.918 1.00 137.36 ? 233 PRO A CG  1 
ATOM   1836 C CD  . PRO A 1 232 ? 125.193 128.255 128.891 1.00 138.73 ? 233 PRO A CD  1 
ATOM   1837 N N   . GLY A 1 233 ? 123.610 130.728 131.160 1.00 151.08 ? 234 GLY A N   1 
ATOM   1838 C CA  . GLY A 1 233 ? 123.356 131.541 132.330 1.00 150.32 ? 234 GLY A CA  1 
ATOM   1839 C C   . GLY A 1 233 ? 123.583 130.807 133.636 1.00 154.72 ? 234 GLY A C   1 
ATOM   1840 O O   . GLY A 1 233 ? 124.049 131.419 134.606 1.00 149.22 ? 234 GLY A O   1 
ATOM   1841 N N   . TRP A 1 234 ? 123.245 129.519 133.686 1.00 157.32 ? 235 TRP A N   1 
ATOM   1842 C CA  . TRP A 1 234 ? 123.582 128.685 134.833 1.00 158.21 ? 235 TRP A CA  1 
ATOM   1843 C C   . TRP A 1 234 ? 125.092 128.522 134.929 1.00 159.08 ? 235 TRP A C   1 
ATOM   1844 O O   . TRP A 1 234 ? 125.759 128.248 133.926 1.00 159.77 ? 235 TRP A O   1 
ATOM   1845 C CB  . TRP A 1 234 ? 122.909 127.319 134.720 1.00 158.38 ? 235 TRP A CB  1 
ATOM   1846 C CG  . TRP A 1 234 ? 121.419 127.331 134.902 1.00 170.42 ? 235 TRP A CG  1 
ATOM   1847 C CD1 . TRP A 1 234 ? 120.472 127.384 133.921 1.00 169.07 ? 235 TRP A CD1 1 
ATOM   1848 C CD2 . TRP A 1 234 ? 120.707 127.236 136.144 1.00 174.84 ? 235 TRP A CD2 1 
ATOM   1849 N NE1 . TRP A 1 234 ? 119.214 127.355 134.477 1.00 173.08 ? 235 TRP A NE1 1 
ATOM   1850 C CE2 . TRP A 1 234 ? 119.331 127.262 135.839 1.00 174.73 ? 235 TRP A CE2 1 
ATOM   1851 C CE3 . TRP A 1 234 ? 121.100 127.144 137.484 1.00 169.49 ? 235 TRP A CE3 1 
ATOM   1852 C CZ2 . TRP A 1 234 ? 118.347 127.199 136.826 1.00 171.20 ? 235 TRP A CZ2 1 
ATOM   1853 C CZ3 . TRP A 1 234 ? 120.120 127.081 138.462 1.00 162.03 ? 235 TRP A CZ3 1 
ATOM   1854 C CH2 . TRP A 1 234 ? 118.761 127.109 138.127 1.00 163.80 ? 235 TRP A CH2 1 
ATOM   1855 N N   . LEU A 1 235 ? 125.629 128.701 136.133 1.00 159.29 ? 236 LEU A N   1 
ATOM   1856 C CA  . LEU A 1 235 ? 127.054 128.502 136.352 1.00 154.98 ? 236 LEU A CA  1 
ATOM   1857 C C   . LEU A 1 235 ? 127.385 127.018 136.292 1.00 152.18 ? 236 LEU A C   1 
ATOM   1858 O O   . LEU A 1 235 ? 126.519 126.163 136.496 1.00 157.72 ? 236 LEU A O   1 
ATOM   1859 C CB  . LEU A 1 235 ? 127.479 129.085 137.703 1.00 152.35 ? 236 LEU A CB  1 
ATOM   1860 C CG  . LEU A 1 235 ? 127.441 130.605 137.893 1.00 153.00 ? 236 LEU A CG  1 
ATOM   1861 C CD1 . LEU A 1 235 ? 126.112 131.071 138.477 1.00 150.67 ? 236 LEU A CD1 1 
ATOM   1862 C CD2 . LEU A 1 235 ? 128.598 131.060 138.769 1.00 154.89 ? 236 LEU A CD2 1 
ATOM   1863 N N   . SER A 1 236 ? 128.646 126.712 136.006 1.00 143.74 ? 237 SER A N   1 
ATOM   1864 C CA  . SER A 1 236 ? 129.060 125.324 135.892 1.00 148.17 ? 237 SER A CA  1 
ATOM   1865 C C   . SER A 1 236 ? 129.171 124.683 137.275 1.00 146.47 ? 237 SER A C   1 
ATOM   1866 O O   . SER A 1 236 ? 129.028 125.337 138.313 1.00 146.55 ? 237 SER A O   1 
ATOM   1867 C CB  . SER A 1 236 ? 130.391 125.220 135.147 1.00 154.22 ? 237 SER A CB  1 
ATOM   1868 O OG  . SER A 1 236 ? 131.459 125.717 135.934 1.00 156.46 ? 237 SER A OG  1 
ATOM   1869 N N   . ARG A 1 237 ? 129.425 123.372 137.276 1.00 144.34 ? 238 ARG A N   1 
ATOM   1870 C CA  . ARG A 1 237 ? 129.572 122.649 138.534 1.00 140.70 ? 238 ARG A CA  1 
ATOM   1871 C C   . ARG A 1 237 ? 130.864 123.022 139.247 1.00 142.47 ? 238 ARG A C   1 
ATOM   1872 O O   . ARG A 1 237 ? 130.955 122.894 140.472 1.00 141.66 ? 238 ARG A O   1 
ATOM   1873 C CB  . ARG A 1 237 ? 129.515 121.141 138.280 1.00 141.29 ? 238 ARG A CB  1 
ATOM   1874 C CG  . ARG A 1 237 ? 128.994 120.308 139.450 1.00 140.55 ? 238 ARG A CG  1 
ATOM   1875 C CD  . ARG A 1 237 ? 127.665 120.811 140.021 1.00 140.81 ? 238 ARG A CD  1 
ATOM   1876 N NE  . ARG A 1 237 ? 126.654 121.074 139.002 1.00 137.59 ? 238 ARG A NE  1 
ATOM   1877 C CZ  . ARG A 1 237 ? 125.598 121.856 139.181 1.00 131.32 ? 238 ARG A CZ  1 
ATOM   1878 N NH1 . ARG A 1 237 ? 125.380 122.471 140.331 1.00 128.22 ? 238 ARG A NH1 1 
ATOM   1879 N NH2 . ARG A 1 237 ? 124.740 122.026 138.179 1.00 126.80 ? 238 ARG A NH2 1 
ATOM   1880 N N   . GLU A 1 238 ? 131.870 123.485 138.502 1.00 147.19 ? 239 GLU A N   1 
ATOM   1881 C CA  . GLU A 1 238 ? 133.108 123.932 139.130 1.00 148.12 ? 239 GLU A CA  1 
ATOM   1882 C C   . GLU A 1 238 ? 132.931 125.289 139.798 1.00 142.14 ? 239 GLU A C   1 
ATOM   1883 O O   . GLU A 1 238 ? 133.532 125.553 140.844 1.00 135.13 ? 239 GLU A O   1 
ATOM   1884 C CB  . GLU A 1 238 ? 134.230 123.992 138.094 1.00 150.57 ? 239 GLU A CB  1 
ATOM   1885 C CG  . GLU A 1 238 ? 134.804 122.639 137.713 1.00 155.12 ? 239 GLU A CG  1 
ATOM   1886 C CD  . GLU A 1 238 ? 135.920 122.750 136.692 1.00 161.39 ? 239 GLU A CD  1 
ATOM   1887 O OE1 . GLU A 1 238 ? 136.036 123.815 136.051 1.00 160.25 ? 239 GLU A OE1 1 
ATOM   1888 O OE2 . GLU A 1 238 ? 136.682 121.773 136.533 1.00 162.87 ? 239 GLU A OE2 1 
ATOM   1889 N N   . GLN A 1 239 ? 132.108 126.159 139.209 1.00 146.31 ? 240 GLN A N   1 
ATOM   1890 C CA  . GLN A 1 239 ? 131.987 127.526 139.709 1.00 147.54 ? 240 GLN A CA  1 
ATOM   1891 C C   . GLN A 1 239 ? 131.179 127.583 140.999 1.00 143.41 ? 240 GLN A C   1 
ATOM   1892 O O   . GLN A 1 239 ? 131.445 128.421 141.868 1.00 136.72 ? 240 GLN A O   1 
ATOM   1893 C CB  . GLN A 1 239 ? 131.355 128.415 138.640 1.00 150.20 ? 240 GLN A CB  1 
ATOM   1894 C CG  . GLN A 1 239 ? 132.233 128.629 137.418 1.00 150.64 ? 240 GLN A CG  1 
ATOM   1895 C CD  . GLN A 1 239 ? 131.611 129.573 136.408 1.00 157.69 ? 240 GLN A CD  1 
ATOM   1896 O OE1 . GLN A 1 239 ? 130.406 129.527 136.156 1.00 157.98 ? 240 GLN A OE1 1 
ATOM   1897 N NE2 . GLN A 1 239 ? 132.433 130.436 135.821 1.00 156.21 ? 240 GLN A NE2 1 
ATOM   1898 N N   . VAL A 1 240 ? 130.178 126.710 141.137 1.00 145.46 ? 241 VAL A N   1 
ATOM   1899 C CA  . VAL A 1 240 ? 129.363 126.697 142.348 1.00 140.27 ? 241 VAL A CA  1 
ATOM   1900 C C   . VAL A 1 240 ? 130.157 126.134 143.526 1.00 139.63 ? 241 VAL A C   1 
ATOM   1901 O O   . VAL A 1 240 ? 130.026 126.608 144.660 1.00 141.08 ? 241 VAL A O   1 
ATOM   1902 C CB  . VAL A 1 240 ? 128.041 125.936 142.093 1.00 140.66 ? 241 VAL A CB  1 
ATOM   1903 C CG1 . VAL A 1 240 ? 128.280 124.529 141.556 1.00 137.29 ? 241 VAL A CG1 1 
ATOM   1904 C CG2 . VAL A 1 240 ? 127.153 125.903 143.339 1.00 144.86 ? 241 VAL A CG2 1 
ATOM   1905 N N   . PHE A 1 241 ? 131.035 125.159 143.269 1.00 143.82 ? 242 PHE A N   1 
ATOM   1906 C CA  . PHE A 1 241 ? 131.735 124.476 144.355 1.00 143.51 ? 242 PHE A CA  1 
ATOM   1907 C C   . PHE A 1 241 ? 132.841 125.338 144.952 1.00 137.92 ? 242 PHE A C   1 
ATOM   1908 O O   . PHE A 1 241 ? 133.092 125.283 146.161 1.00 136.38 ? 242 PHE A O   1 
ATOM   1909 C CB  . PHE A 1 241 ? 132.307 123.144 143.864 1.00 142.33 ? 242 PHE A CB  1 
ATOM   1910 C CG  . PHE A 1 241 ? 131.268 122.084 143.594 1.00 142.38 ? 242 PHE A CG  1 
ATOM   1911 C CD1 . PHE A 1 241 ? 129.966 122.217 144.062 1.00 146.17 ? 242 PHE A CD1 1 
ATOM   1912 C CD2 . PHE A 1 241 ? 131.611 120.932 142.902 1.00 146.50 ? 242 PHE A CD2 1 
ATOM   1913 C CE1 . PHE A 1 241 ? 129.022 121.234 143.822 1.00 150.05 ? 242 PHE A CE1 1 
ATOM   1914 C CE2 . PHE A 1 241 ? 130.673 119.944 142.658 1.00 150.68 ? 242 PHE A CE2 1 
ATOM   1915 C CZ  . PHE A 1 241 ? 129.377 120.095 143.121 1.00 151.21 ? 242 PHE A CZ  1 
ATOM   1916 N N   . VAL A 1 242 ? 133.530 126.120 144.118 1.00 136.26 ? 243 VAL A N   1 
ATOM   1917 C CA  . VAL A 1 242 ? 134.589 126.996 144.614 1.00 135.65 ? 243 VAL A CA  1 
ATOM   1918 C C   . VAL A 1 242 ? 133.998 128.133 145.441 1.00 134.44 ? 243 VAL A C   1 
ATOM   1919 O O   . VAL A 1 242 ? 134.552 128.516 146.480 1.00 138.49 ? 243 VAL A O   1 
ATOM   1920 C CB  . VAL A 1 242 ? 135.439 127.510 143.434 1.00 141.04 ? 243 VAL A CB  1 
ATOM   1921 C CG1 . VAL A 1 242 ? 136.486 128.518 143.891 1.00 129.45 ? 243 VAL A CG1 1 
ATOM   1922 C CG2 . VAL A 1 242 ? 136.123 126.347 142.735 1.00 143.05 ? 243 VAL A CG2 1 
ATOM   1923 N N   . LEU A 1 243 ? 132.845 128.659 145.018 1.00 131.29 ? 244 LEU A N   1 
ATOM   1924 C CA  . LEU A 1 243 ? 132.255 129.823 145.675 1.00 125.50 ? 244 LEU A CA  1 
ATOM   1925 C C   . LEU A 1 243 ? 131.717 129.469 147.059 1.00 131.89 ? 244 LEU A C   1 
ATOM   1926 O O   . LEU A 1 243 ? 131.815 130.270 147.996 1.00 136.42 ? 244 LEU A O   1 
ATOM   1927 C CB  . LEU A 1 243 ? 131.158 130.411 144.779 1.00 125.65 ? 244 LEU A CB  1 
ATOM   1928 C CG  . LEU A 1 243 ? 130.454 131.748 145.058 1.00 129.43 ? 244 LEU A CG  1 
ATOM   1929 C CD1 . LEU A 1 243 ? 130.010 132.345 143.735 1.00 135.92 ? 244 LEU A CD1 1 
ATOM   1930 C CD2 . LEU A 1 243 ? 129.236 131.618 145.972 1.00 127.85 ? 244 LEU A CD2 1 
ATOM   1931 N N   . ILE A 1 244 ? 131.146 128.272 147.211 1.00 131.83 ? 245 ILE A N   1 
ATOM   1932 C CA  . ILE A 1 244 ? 130.583 127.904 148.507 1.00 132.72 ? 245 ILE A CA  1 
ATOM   1933 C C   . ILE A 1 244 ? 131.675 127.448 149.467 1.00 130.25 ? 245 ILE A C   1 
ATOM   1934 O O   . ILE A 1 244 ? 131.495 127.501 150.690 1.00 131.33 ? 245 ILE A O   1 
ATOM   1935 C CB  . ILE A 1 244 ? 129.490 126.830 148.347 1.00 135.35 ? 245 ILE A CB  1 
ATOM   1936 C CG1 . ILE A 1 244 ? 130.064 125.542 147.750 1.00 133.63 ? 245 ILE A CG1 1 
ATOM   1937 C CG2 . ILE A 1 244 ? 128.348 127.357 147.492 1.00 135.93 ? 245 ILE A CG2 1 
ATOM   1938 C CD1 . ILE A 1 244 ? 129.102 124.374 147.778 1.00 135.60 ? 245 ILE A CD1 1 
ATOM   1939 N N   . SER A 1 245 ? 132.817 126.999 148.944 1.00 129.73 ? 246 SER A N   1 
ATOM   1940 C CA  . SER A 1 245 ? 133.875 126.496 149.812 1.00 128.38 ? 246 SER A CA  1 
ATOM   1941 C C   . SER A 1 245 ? 134.805 127.615 150.257 1.00 129.90 ? 246 SER A C   1 
ATOM   1942 O O   . SER A 1 245 ? 135.322 127.589 151.381 1.00 133.24 ? 246 SER A O   1 
ATOM   1943 C CB  . SER A 1 245 ? 134.661 125.402 149.096 1.00 137.61 ? 246 SER A CB  1 
ATOM   1944 O OG  . SER A 1 245 ? 135.363 125.927 147.983 1.00 141.73 ? 246 SER A OG  1 
ATOM   1945 N N   . ALA A 1 246 ? 135.040 128.599 149.387 1.00 129.61 ? 247 ALA A N   1 
ATOM   1946 C CA  . ALA A 1 246 ? 135.908 129.713 149.752 1.00 131.97 ? 247 ALA A CA  1 
ATOM   1947 C C   . ALA A 1 246 ? 135.205 130.674 150.701 1.00 130.63 ? 247 ALA A C   1 
ATOM   1948 O O   . ALA A 1 246 ? 135.861 131.377 151.477 1.00 130.95 ? 247 ALA A O   1 
ATOM   1949 C CB  . ALA A 1 246 ? 136.379 130.447 148.498 1.00 135.85 ? 247 ALA A CB  1 
ATOM   1950 N N   . ALA A 1 247 ? 133.874 130.730 150.647 1.00 132.07 ? 248 ALA A N   1 
ATOM   1951 C CA  . ALA A 1 247 ? 133.140 131.631 151.528 1.00 135.49 ? 248 ALA A CA  1 
ATOM   1952 C C   . ALA A 1 247 ? 133.126 131.117 152.962 1.00 131.59 ? 248 ALA A C   1 
ATOM   1953 O O   . ALA A 1 247 ? 133.123 131.909 153.910 1.00 137.19 ? 248 ALA A O   1 
ATOM   1954 C CB  . ALA A 1 247 ? 131.714 131.823 151.012 1.00 137.44 ? 248 ALA A CB  1 
ATOM   1955 N N   . SER A 1 248 ? 133.124 129.794 153.139 1.00 125.58 ? 249 SER A N   1 
ATOM   1956 C CA  . SER A 1 248 ? 133.002 129.228 154.478 1.00 125.96 ? 249 SER A CA  1 
ATOM   1957 C C   . SER A 1 248 ? 134.297 129.366 155.269 1.00 126.69 ? 249 SER A C   1 
ATOM   1958 O O   . SER A 1 248 ? 134.271 129.444 156.503 1.00 125.67 ? 249 SER A O   1 
ATOM   1959 C CB  . SER A 1 248 ? 132.582 127.762 154.387 1.00 134.57 ? 249 SER A CB  1 
ATOM   1960 O OG  . SER A 1 248 ? 131.294 127.638 153.811 1.00 134.03 ? 249 SER A OG  1 
ATOM   1961 N N   . VAL A 1 249 ? 135.442 129.397 154.582 1.00 129.42 ? 250 VAL A N   1 
ATOM   1962 C CA  . VAL A 1 249 ? 136.711 129.475 155.299 1.00 130.76 ? 250 VAL A CA  1 
ATOM   1963 C C   . VAL A 1 249 ? 136.975 130.902 155.780 1.00 134.63 ? 250 VAL A C   1 
ATOM   1964 O O   . VAL A 1 249 ? 137.644 131.104 156.801 1.00 135.27 ? 250 VAL A O   1 
ATOM   1965 C CB  . VAL A 1 249 ? 137.855 128.907 154.426 1.00 127.95 ? 250 VAL A CB  1 
ATOM   1966 C CG1 . VAL A 1 249 ? 138.163 129.792 153.225 1.00 129.13 ? 250 VAL A CG1 1 
ATOM   1967 C CG2 . VAL A 1 249 ? 139.112 128.639 155.255 1.00 127.28 ? 250 VAL A CG2 1 
ATOM   1968 N N   . ASN A 1 250 ? 136.431 131.911 155.092 1.00 134.09 ? 251 ASN A N   1 
ATOM   1969 C CA  . ASN A 1 250 ? 136.563 133.281 155.579 1.00 130.70 ? 251 ASN A CA  1 
ATOM   1970 C C   . ASN A 1 250 ? 135.553 133.576 156.679 1.00 131.90 ? 251 ASN A C   1 
ATOM   1971 O O   . ASN A 1 250 ? 135.763 134.481 157.494 1.00 136.66 ? 251 ASN A O   1 
ATOM   1972 C CB  . ASN A 1 250 ? 136.411 134.275 154.429 1.00 130.69 ? 251 ASN A CB  1 
ATOM   1973 C CG  . ASN A 1 250 ? 137.522 134.160 153.409 1.00 139.65 ? 251 ASN A CG  1 
ATOM   1974 O OD1 . ASN A 1 250 ? 137.292 133.791 152.261 1.00 141.58 ? 251 ASN A OD1 1 
ATOM   1975 N ND2 . ASN A 1 250 ? 138.741 134.480 153.827 1.00 147.22 ? 251 ASN A ND2 1 
ATOM   1976 N N   . LEU A 1 251 ? 134.444 132.834 156.708 1.00 133.17 ? 252 LEU A N   1 
ATOM   1977 C CA  . LEU A 1 251 ? 133.467 133.007 157.778 1.00 137.69 ? 252 LEU A CA  1 
ATOM   1978 C C   . LEU A 1 251 ? 134.002 132.464 159.096 1.00 137.95 ? 252 LEU A C   1 
ATOM   1979 O O   . LEU A 1 251 ? 133.867 133.103 160.145 1.00 138.50 ? 252 LEU A O   1 
ATOM   1980 C CB  . LEU A 1 251 ? 132.153 132.322 157.403 1.00 139.73 ? 252 LEU A CB  1 
ATOM   1981 C CG  . LEU A 1 251 ? 130.983 132.526 158.368 1.00 144.81 ? 252 LEU A CG  1 
ATOM   1982 C CD1 . LEU A 1 251 ? 130.352 133.896 158.170 1.00 145.70 ? 252 LEU A CD1 1 
ATOM   1983 C CD2 . LEU A 1 251 ? 129.946 131.426 158.196 1.00 141.90 ? 252 LEU A CD2 1 
ATOM   1984 N N   . GLY A 1 252 ? 134.619 131.281 159.059 1.00 135.20 ? 253 GLY A N   1 
ATOM   1985 C CA  . GLY A 1 252 ? 135.168 130.704 160.273 1.00 133.97 ? 253 GLY A CA  1 
ATOM   1986 C C   . GLY A 1 252 ? 136.452 131.368 160.726 1.00 137.16 ? 253 GLY A C   1 
ATOM   1987 O O   . GLY A 1 252 ? 136.819 131.277 161.900 1.00 143.33 ? 253 GLY A O   1 
ATOM   1988 N N   . SER A 1 253 ? 137.158 132.030 159.806 1.00 137.23 ? 254 SER A N   1 
ATOM   1989 C CA  . SER A 1 253 ? 138.373 132.749 160.175 1.00 140.52 ? 254 SER A CA  1 
ATOM   1990 C C   . SER A 1 253 ? 138.047 133.977 161.014 1.00 139.87 ? 254 SER A C   1 
ATOM   1991 O O   . SER A 1 253 ? 138.712 134.254 162.018 1.00 140.46 ? 254 SER A O   1 
ATOM   1992 C CB  . SER A 1 253 ? 139.153 133.143 158.922 1.00 145.92 ? 254 SER A CB  1 
ATOM   1993 O OG  . SER A 1 253 ? 140.078 134.179 159.202 1.00 153.16 ? 254 SER A OG  1 
ATOM   1994 N N   . MET A 1 254 ? 137.028 134.747 160.521 1.00 146.67 ? 255 MET A N   1 
ATOM   1995 C CA  . MET A 1 254 ? 136.605 135.830 161.403 1.00 147.32 ? 255 MET A CA  1 
ATOM   1996 C C   . MET A 1 254 ? 135.806 135.303 162.585 1.00 148.53 ? 255 MET A C   1 
ATOM   1997 O O   . MET A 1 254 ? 135.689 135.986 163.608 1.00 144.49 ? 255 MET A O   1 
ATOM   1998 C CB  . MET A 1 254 ? 135.784 136.860 160.627 1.00 144.00 ? 255 MET A CB  1 
ATOM   1999 C CG  . MET A 1 254 ? 136.164 137.005 159.159 1.00 146.65 ? 255 MET A CG  1 
ATOM   2000 S SD  . MET A 1 254 ? 137.900 136.656 158.822 1.00 146.60 ? 255 MET A SD  1 
ATOM   2001 C CE  . MET A 1 254 ? 138.680 138.142 159.448 1.00 145.12 ? 255 MET A CE  1 
ATOM   2002 N N   . MET A 1 255 ? 135.254 134.218 162.627 1.00 152.37 ? 256 MET A N   1 
ATOM   2003 C CA  . MET A 1 255 ? 134.453 133.744 163.751 1.00 154.85 ? 256 MET A CA  1 
ATOM   2004 C C   . MET A 1 255 ? 135.314 133.550 164.993 1.00 154.63 ? 256 MET A C   1 
ATOM   2005 O O   . MET A 1 255 ? 134.945 133.979 166.092 1.00 155.23 ? 256 MET A O   1 
ATOM   2006 C CB  . MET A 1 255 ? 133.752 132.439 163.372 1.00 153.07 ? 256 MET A CB  1 
ATOM   2007 C CG  . MET A 1 255 ? 132.738 131.937 164.383 1.00 158.05 ? 256 MET A CG  1 
ATOM   2008 S SD  . MET A 1 255 ? 131.307 133.023 164.520 1.00 168.08 ? 256 MET A SD  1 
ATOM   2009 C CE  . MET A 1 255 ? 130.714 132.592 166.153 1.00 162.31 ? 256 MET A CE  1 
ATOM   2010 N N   . CYS A 1 256 ? 136.470 132.903 164.836 1.00 153.49 ? 257 CYS A N   1 
ATOM   2011 C CA  . CYS A 1 256 ? 137.366 132.677 165.962 1.00 158.25 ? 257 CYS A CA  1 
ATOM   2012 C C   . CYS A 1 256 ? 138.257 133.876 166.255 1.00 161.10 ? 257 CYS A C   1 
ATOM   2013 O O   . CYS A 1 256 ? 138.867 133.930 167.329 1.00 165.10 ? 257 CYS A O   1 
ATOM   2014 C CB  . CYS A 1 256 ? 138.232 131.443 165.705 1.00 162.00 ? 257 CYS A CB  1 
ATOM   2015 S SG  . CYS A 1 256 ? 139.459 131.653 164.394 1.00 163.91 ? 257 CYS A SG  1 
ATOM   2016 N N   . TYR A 1 257 ? 138.352 134.831 165.332 1.00 157.02 ? 258 TYR A N   1 
ATOM   2017 C CA  . TYR A 1 257 ? 139.140 136.036 165.548 1.00 155.21 ? 258 TYR A CA  1 
ATOM   2018 C C   . TYR A 1 257 ? 138.332 137.135 166.227 1.00 154.18 ? 258 TYR A C   1 
ATOM   2019 O O   . TYR A 1 257 ? 138.911 138.124 166.687 1.00 149.56 ? 258 TYR A O   1 
ATOM   2020 C CB  . TYR A 1 257 ? 139.707 136.524 164.203 1.00 152.65 ? 258 TYR A CB  1 
ATOM   2021 C CG  . TYR A 1 257 ? 140.788 137.583 164.287 1.00 155.99 ? 258 TYR A CG  1 
ATOM   2022 C CD1 . TYR A 1 257 ? 142.113 137.226 164.513 1.00 155.18 ? 258 TYR A CD1 1 
ATOM   2023 C CD2 . TYR A 1 257 ? 140.495 138.931 164.094 1.00 159.16 ? 258 TYR A CD2 1 
ATOM   2024 C CE1 . TYR A 1 257 ? 143.112 138.181 164.581 1.00 153.72 ? 258 TYR A CE1 1 
ATOM   2025 C CE2 . TYR A 1 257 ? 141.488 139.895 164.162 1.00 157.26 ? 258 TYR A CE2 1 
ATOM   2026 C CZ  . TYR A 1 257 ? 142.794 139.513 164.403 1.00 154.03 ? 258 TYR A CZ  1 
ATOM   2027 O OH  . TYR A 1 257 ? 143.789 140.461 164.468 1.00 152.23 ? 258 TYR A OH  1 
ATOM   2028 N N   . SER A 1 258 ? 137.018 136.957 166.354 1.00 161.49 ? 259 SER A N   1 
ATOM   2029 C CA  . SER A 1 258 ? 136.151 137.935 167.000 1.00 168.61 ? 259 SER A CA  1 
ATOM   2030 C C   . SER A 1 258 ? 136.166 137.830 168.520 1.00 166.81 ? 259 SER A C   1 
ATOM   2031 O O   . SER A 1 258 ? 135.453 138.592 169.184 1.00 159.22 ? 259 SER A O   1 
ATOM   2032 C CB  . SER A 1 258 ? 134.715 137.781 166.488 1.00 164.22 ? 259 SER A CB  1 
ATOM   2033 O OG  . SER A 1 258 ? 134.667 137.860 165.073 1.00 156.04 ? 259 SER A OG  1 
ATOM   2034 N N   . ILE A 1 259 ? 136.946 136.906 169.083 1.00 164.46 ? 260 ILE A N   1 
ATOM   2035 C CA  . ILE A 1 259 ? 137.098 136.756 170.525 1.00 167.12 ? 260 ILE A CA  1 
ATOM   2036 C C   . ILE A 1 259 ? 138.529 137.055 170.974 1.00 165.10 ? 260 ILE A C   1 
ATOM   2037 O O   . ILE A 1 259 ? 138.746 137.654 172.033 1.00 161.10 ? 260 ILE A O   1 
ATOM   2038 C CB  . ILE A 1 259 ? 136.627 135.352 171.001 1.00 167.88 ? 260 ILE A CB  1 
ATOM   2039 C CG1 . ILE A 1 259 ? 136.595 135.254 172.531 1.00 167.80 ? 260 ILE A CG1 1 
ATOM   2040 C CG2 . ILE A 1 259 ? 137.375 134.197 170.316 1.00 165.68 ? 260 ILE A CG2 1 
ATOM   2041 C CD1 . ILE A 1 259 ? 135.850 134.045 173.048 1.00 161.15 ? 260 ILE A CD1 1 
ATOM   2042 N N   . LEU A 1 260 ? 139.518 136.681 170.161 1.00 166.44 ? 261 LEU A N   1 
ATOM   2043 C CA  . LEU A 1 260 ? 140.923 136.942 170.456 1.00 164.88 ? 261 LEU A CA  1 
ATOM   2044 C C   . LEU A 1 260 ? 141.610 137.789 169.391 1.00 156.01 ? 261 LEU A C   1 
ATOM   2045 O O   . LEU A 1 260 ? 142.743 137.478 169.011 1.00 149.08 ? 261 LEU A O   1 
ATOM   2046 C CB  . LEU A 1 260 ? 141.698 135.626 170.631 1.00 168.12 ? 261 LEU A CB  1 
ATOM   2047 C CG  . LEU A 1 260 ? 141.760 134.892 171.982 1.00 167.61 ? 261 LEU A CG  1 
ATOM   2048 C CD1 . LEU A 1 260 ? 142.481 135.747 173.019 1.00 165.37 ? 261 LEU A CD1 1 
ATOM   2049 C CD2 . LEU A 1 260 ? 140.404 134.433 172.507 1.00 164.50 ? 261 LEU A CD2 1 
ATOM   2050 N N   . GLY A 1 261 ? 140.961 138.839 168.902 1.00 153.30 ? 262 GLY A N   1 
ATOM   2051 C CA  . GLY A 1 261 ? 141.559 139.699 167.897 1.00 147.51 ? 262 GLY A CA  1 
ATOM   2052 C C   . GLY A 1 261 ? 142.648 140.596 168.448 1.00 146.48 ? 262 GLY A C   1 
ATOM   2053 O O   . GLY A 1 261 ? 143.810 140.200 168.523 1.00 149.40 ? 262 GLY A O   1 
ATOM   2054 N N   . GLY A 1 279 ? 156.947 142.787 172.683 1.00 179.46 ? 280 GLY A N   1 
ATOM   2055 C CA  . GLY A 1 279 ? 157.721 143.592 171.756 1.00 177.83 ? 280 GLY A CA  1 
ATOM   2056 C C   . GLY A 1 279 ? 158.490 142.766 170.744 1.00 173.45 ? 280 GLY A C   1 
ATOM   2057 O O   . GLY A 1 279 ? 158.422 143.018 169.541 1.00 172.51 ? 280 GLY A O   1 
ATOM   2058 N N   . MET A 1 280 ? 159.226 141.767 171.236 1.00 167.26 ? 281 MET A N   1 
ATOM   2059 C CA  . MET A 1 280 ? 160.005 140.916 170.343 1.00 168.85 ? 281 MET A CA  1 
ATOM   2060 C C   . MET A 1 280 ? 159.129 139.903 169.618 1.00 173.01 ? 281 MET A C   1 
ATOM   2061 O O   . MET A 1 280 ? 159.577 139.286 168.644 1.00 173.90 ? 281 MET A O   1 
ATOM   2062 C CB  . MET A 1 280 ? 161.105 140.202 171.127 1.00 161.46 ? 281 MET A CB  1 
ATOM   2063 C CG  . MET A 1 280 ? 162.187 141.126 171.662 1.00 151.38 ? 281 MET A CG  1 
ATOM   2064 S SD  . MET A 1 280 ? 163.461 140.243 172.581 1.00 141.73 ? 281 MET A SD  1 
ATOM   2065 C CE  . MET A 1 280 ? 164.487 141.603 173.131 1.00 131.55 ? 281 MET A CE  1 
ATOM   2066 N N   . ILE A 1 281 ? 157.893 139.705 170.083 1.00 173.32 ? 282 ILE A N   1 
ATOM   2067 C CA  . ILE A 1 281 ? 156.983 138.765 169.432 1.00 177.60 ? 282 ILE A CA  1 
ATOM   2068 C C   . ILE A 1 281 ? 156.524 139.317 168.086 1.00 172.32 ? 282 ILE A C   1 
ATOM   2069 O O   . ILE A 1 281 ? 156.462 138.592 167.085 1.00 169.31 ? 282 ILE A O   1 
ATOM   2070 C CB  . ILE A 1 281 ? 155.791 138.452 170.358 1.00 181.75 ? 282 ILE A CB  1 
ATOM   2071 C CG1 . ILE A 1 281 ? 156.289 137.866 171.680 1.00 180.74 ? 282 ILE A CG1 1 
ATOM   2072 C CG2 . ILE A 1 281 ? 154.817 137.486 169.696 1.00 183.12 ? 282 ILE A CG2 1 
ATOM   2073 C CD1 . ILE A 1 281 ? 157.049 136.567 171.526 1.00 182.67 ? 282 ILE A CD1 1 
ATOM   2074 N N   . PHE A 1 282 ? 156.210 140.616 168.042 1.00 169.95 ? 283 PHE A N   1 
ATOM   2075 C CA  . PHE A 1 282 ? 155.724 141.228 166.808 1.00 171.21 ? 283 PHE A CA  1 
ATOM   2076 C C   . PHE A 1 282 ? 156.828 141.330 165.763 1.00 174.88 ? 283 PHE A C   1 
ATOM   2077 O O   . PHE A 1 282 ? 156.558 141.261 164.558 1.00 173.39 ? 283 PHE A O   1 
ATOM   2078 C CB  . PHE A 1 282 ? 155.133 142.604 167.105 1.00 171.60 ? 283 PHE A CB  1 
ATOM   2079 C CG  . PHE A 1 282 ? 153.771 142.552 167.730 1.00 179.37 ? 283 PHE A CG  1 
ATOM   2080 C CD1 . PHE A 1 282 ? 152.792 141.718 167.213 1.00 178.94 ? 283 PHE A CD1 1 
ATOM   2081 C CD2 . PHE A 1 282 ? 153.472 143.330 168.838 1.00 185.92 ? 283 PHE A CD2 1 
ATOM   2082 C CE1 . PHE A 1 282 ? 151.534 141.663 167.787 1.00 185.07 ? 283 PHE A CE1 1 
ATOM   2083 C CE2 . PHE A 1 282 ? 152.216 143.281 169.419 1.00 189.12 ? 283 PHE A CE2 1 
ATOM   2084 C CZ  . PHE A 1 282 ? 151.246 142.446 168.892 1.00 189.19 ? 283 PHE A CZ  1 
ATOM   2085 N N   . GLY A 1 283 ? 158.074 141.514 166.203 1.00 178.34 ? 284 GLY A N   1 
ATOM   2086 C CA  . GLY A 1 283 ? 159.193 141.405 165.281 1.00 172.07 ? 284 GLY A CA  1 
ATOM   2087 C C   . GLY A 1 283 ? 159.382 139.989 164.774 1.00 159.13 ? 284 GLY A C   1 
ATOM   2088 O O   . GLY A 1 283 ? 159.759 139.775 163.620 1.00 150.84 ? 284 GLY A O   1 
ATOM   2089 N N   . CYS A 1 284 ? 159.121 139.002 165.634 1.00 163.57 ? 285 CYS A N   1 
ATOM   2090 C CA  . CYS A 1 284 ? 159.182 137.610 165.208 1.00 170.43 ? 285 CYS A CA  1 
ATOM   2091 C C   . CYS A 1 284 ? 158.000 137.252 164.315 1.00 165.52 ? 285 CYS A C   1 
ATOM   2092 O O   . CYS A 1 284 ? 158.135 136.434 163.398 1.00 160.70 ? 285 CYS A O   1 
ATOM   2093 C CB  . CYS A 1 284 ? 159.233 136.691 166.430 1.00 176.60 ? 285 CYS A CB  1 
ATOM   2094 S SG  . CYS A 1 284 ? 159.326 134.924 166.052 1.00 188.19 ? 285 CYS A SG  1 
ATOM   2095 N N   . PHE A 1 285 ? 156.830 137.842 164.576 1.00 161.27 ? 286 PHE A N   1 
ATOM   2096 C CA  . PHE A 1 285 ? 155.647 137.522 163.782 1.00 157.41 ? 286 PHE A CA  1 
ATOM   2097 C C   . PHE A 1 285 ? 155.761 138.093 162.374 1.00 153.44 ? 286 PHE A C   1 
ATOM   2098 O O   . PHE A 1 285 ? 155.527 137.385 161.390 1.00 152.93 ? 286 PHE A O   1 
ATOM   2099 C CB  . PHE A 1 285 ? 154.383 138.029 164.497 1.00 160.92 ? 286 PHE A CB  1 
ATOM   2100 C CG  . PHE A 1 285 ? 153.114 137.985 163.657 1.00 161.33 ? 286 PHE A CG  1 
ATOM   2101 C CD1 . PHE A 1 285 ? 152.693 139.083 162.902 1.00 158.72 ? 286 PHE A CD1 1 
ATOM   2102 C CD2 . PHE A 1 285 ? 152.346 136.830 163.623 1.00 161.63 ? 286 PHE A CD2 1 
ATOM   2103 C CE1 . PHE A 1 285 ? 151.543 139.022 162.139 1.00 152.22 ? 286 PHE A CE1 1 
ATOM   2104 C CE2 . PHE A 1 285 ? 151.190 136.768 162.863 1.00 157.33 ? 286 PHE A CE2 1 
ATOM   2105 C CZ  . PHE A 1 285 ? 150.791 137.864 162.121 1.00 152.62 ? 286 PHE A CZ  1 
ATOM   2106 N N   . ALA A 1 286 ? 156.129 139.373 162.264 1.00 154.79 ? 287 ALA A N   1 
ATOM   2107 C CA  . ALA A 1 286 ? 155.994 140.088 160.997 1.00 152.25 ? 287 ALA A CA  1 
ATOM   2108 C C   . ALA A 1 286 ? 157.020 139.627 159.970 1.00 147.06 ? 287 ALA A C   1 
ATOM   2109 O O   . ALA A 1 286 ? 156.748 139.639 158.764 1.00 138.29 ? 287 ALA A O   1 
ATOM   2110 C CB  . ALA A 1 286 ? 156.112 141.592 161.233 1.00 151.00 ? 287 ALA A CB  1 
ATOM   2111 N N   . LEU A 1 287 ? 158.208 139.230 160.426 1.00 153.56 ? 288 LEU A N   1 
ATOM   2112 C CA  . LEU A 1 287 ? 159.217 138.728 159.501 1.00 154.25 ? 288 LEU A CA  1 
ATOM   2113 C C   . LEU A 1 287 ? 158.838 137.354 158.961 1.00 149.06 ? 288 LEU A C   1 
ATOM   2114 O O   . LEU A 1 287 ? 159.000 137.086 157.765 1.00 143.00 ? 288 LEU A O   1 
ATOM   2115 C CB  . LEU A 1 287 ? 160.582 138.681 160.188 1.00 159.17 ? 288 LEU A CB  1 
ATOM   2116 C CG  . LEU A 1 287 ? 161.767 138.244 159.323 1.00 161.07 ? 288 LEU A CG  1 
ATOM   2117 C CD1 . LEU A 1 287 ? 161.989 139.227 158.182 1.00 156.62 ? 288 LEU A CD1 1 
ATOM   2118 C CD2 . LEU A 1 287 ? 163.024 138.099 160.164 1.00 157.32 ? 288 LEU A CD2 1 
ATOM   2119 N N   . PHE A 1 288 ? 158.326 136.473 159.823 1.00 148.60 ? 289 PHE A N   1 
ATOM   2120 C CA  . PHE A 1 288 ? 157.992 135.125 159.375 1.00 149.06 ? 289 PHE A CA  1 
ATOM   2121 C C   . PHE A 1 288 ? 156.574 135.043 158.820 1.00 145.21 ? 289 PHE A C   1 
ATOM   2122 O O   . PHE A 1 288 ? 156.189 134.014 158.256 1.00 147.60 ? 289 PHE A O   1 
ATOM   2123 C CB  . PHE A 1 288 ? 158.196 134.123 160.511 1.00 154.09 ? 289 PHE A CB  1 
ATOM   2124 C CG  . PHE A 1 288 ? 159.641 133.895 160.861 1.00 161.33 ? 289 PHE A CG  1 
ATOM   2125 C CD1 . PHE A 1 288 ? 160.422 133.041 160.096 1.00 163.20 ? 289 PHE A CD1 1 
ATOM   2126 C CD2 . PHE A 1 288 ? 160.219 134.533 161.947 1.00 164.13 ? 289 PHE A CD2 1 
ATOM   2127 C CE1 . PHE A 1 288 ? 161.754 132.825 160.409 1.00 168.82 ? 289 PHE A CE1 1 
ATOM   2128 C CE2 . PHE A 1 288 ? 161.550 134.323 162.267 1.00 166.73 ? 289 PHE A CE2 1 
ATOM   2129 C CZ  . PHE A 1 288 ? 162.318 133.468 161.496 1.00 169.88 ? 289 PHE A CZ  1 
ATOM   2130 N N   . GLU A 1 289 ? 155.772 136.098 158.981 1.00 141.16 ? 290 GLU A N   1 
ATOM   2131 C CA  . GLU A 1 289 ? 154.551 136.200 158.187 1.00 137.23 ? 290 GLU A CA  1 
ATOM   2132 C C   . GLU A 1 289 ? 154.867 136.635 156.764 1.00 134.35 ? 290 GLU A C   1 
ATOM   2133 O O   . GLU A 1 289 ? 154.264 136.140 155.805 1.00 132.12 ? 290 GLU A O   1 
ATOM   2134 C CB  . GLU A 1 289 ? 153.558 137.170 158.840 1.00 147.61 ? 290 GLU A CB  1 
ATOM   2135 C CG  . GLU A 1 289 ? 152.249 137.460 158.070 1.00 150.52 ? 290 GLU A CG  1 
ATOM   2136 C CD  . GLU A 1 289 ? 151.275 136.294 157.932 1.00 148.14 ? 290 GLU A CD  1 
ATOM   2137 O OE1 . GLU A 1 289 ? 151.531 135.191 158.449 1.00 147.18 ? 290 GLU A OE1 1 
ATOM   2138 O OE2 . GLU A 1 289 ? 150.226 136.494 157.287 1.00 145.50 ? 290 GLU A OE2 1 
ATOM   2139 N N   . LEU A 1 290 ? 155.811 137.565 156.612 1.00 137.91 ? 291 LEU A N   1 
ATOM   2140 C CA  . LEU A 1 290 ? 156.235 138.004 155.287 1.00 132.47 ? 291 LEU A CA  1 
ATOM   2141 C C   . LEU A 1 290 ? 157.004 136.905 154.566 1.00 130.63 ? 291 LEU A C   1 
ATOM   2142 O O   . LEU A 1 290 ? 156.890 136.751 153.344 1.00 131.99 ? 291 LEU A O   1 
ATOM   2143 C CB  . LEU A 1 290 ? 157.086 139.268 155.413 1.00 131.83 ? 291 LEU A CB  1 
ATOM   2144 C CG  . LEU A 1 290 ? 157.587 139.927 154.129 1.00 130.18 ? 291 LEU A CG  1 
ATOM   2145 C CD1 . LEU A 1 290 ? 156.422 140.395 153.288 1.00 120.07 ? 291 LEU A CD1 1 
ATOM   2146 C CD2 . LEU A 1 290 ? 158.514 141.085 154.455 1.00 136.02 ? 291 LEU A CD2 1 
ATOM   2147 N N   . LEU A 1 291 ? 157.801 136.134 155.310 1.00 129.33 ? 292 LEU A N   1 
ATOM   2148 C CA  . LEU A 1 291 ? 158.571 135.055 154.701 1.00 129.00 ? 292 LEU A CA  1 
ATOM   2149 C C   . LEU A 1 291 ? 157.674 133.902 154.271 1.00 130.09 ? 292 LEU A C   1 
ATOM   2150 O O   . LEU A 1 291 ? 157.866 133.332 153.191 1.00 132.63 ? 292 LEU A O   1 
ATOM   2151 C CB  . LEU A 1 291 ? 159.646 134.564 155.671 1.00 137.15 ? 292 LEU A CB  1 
ATOM   2152 C CG  . LEU A 1 291 ? 160.578 133.465 155.155 1.00 138.76 ? 292 LEU A CG  1 
ATOM   2153 C CD1 . LEU A 1 291 ? 161.381 133.954 153.960 1.00 135.84 ? 292 LEU A CD1 1 
ATOM   2154 C CD2 . LEU A 1 291 ? 161.501 132.979 156.263 1.00 142.45 ? 292 LEU A CD2 1 
ATOM   2155 N N   . ALA A 1 292 ? 156.683 133.549 155.095 1.00 129.63 ? 293 ALA A N   1 
ATOM   2156 C CA  . ALA A 1 292 ? 155.795 132.445 154.745 1.00 122.83 ? 293 ALA A CA  1 
ATOM   2157 C C   . ALA A 1 292 ? 154.834 132.836 153.631 1.00 124.06 ? 293 ALA A C   1 
ATOM   2158 O O   . ALA A 1 292 ? 154.369 131.978 152.877 1.00 126.16 ? 293 ALA A O   1 
ATOM   2159 C CB  . ALA A 1 292 ? 155.020 131.973 155.973 1.00 129.52 ? 293 ALA A CB  1 
ATOM   2160 N N   . SER A 1 293 ? 154.510 134.124 153.518 1.00 128.18 ? 294 SER A N   1 
ATOM   2161 C CA  . SER A 1 293 ? 153.662 134.558 152.414 1.00 123.43 ? 294 SER A CA  1 
ATOM   2162 C C   . SER A 1 293 ? 154.433 134.611 151.103 1.00 127.39 ? 294 SER A C   1 
ATOM   2163 O O   . SER A 1 293 ? 153.829 134.525 150.028 1.00 127.10 ? 294 SER A O   1 
ATOM   2164 C CB  . SER A 1 293 ? 153.049 135.922 152.722 1.00 122.37 ? 294 SER A CB  1 
ATOM   2165 O OG  . SER A 1 293 ? 152.406 135.918 153.984 1.00 130.35 ? 294 SER A OG  1 
ATOM   2166 N N   . LEU A 1 294 ? 155.759 134.749 151.166 1.00 131.78 ? 295 LEU A N   1 
ATOM   2167 C CA  . LEU A 1 294 ? 156.544 134.931 149.951 1.00 128.52 ? 295 LEU A CA  1 
ATOM   2168 C C   . LEU A 1 294 ? 156.877 133.599 149.289 1.00 129.28 ? 295 LEU A C   1 
ATOM   2169 O O   . LEU A 1 294 ? 156.440 133.330 148.165 1.00 132.45 ? 295 LEU A O   1 
ATOM   2170 C CB  . LEU A 1 294 ? 157.823 135.709 150.267 1.00 134.95 ? 295 LEU A CB  1 
ATOM   2171 C CG  . LEU A 1 294 ? 158.403 136.576 149.145 1.00 140.73 ? 295 LEU A CG  1 
ATOM   2172 C CD1 . LEU A 1 294 ? 157.312 137.355 148.416 1.00 134.55 ? 295 LEU A CD1 1 
ATOM   2173 C CD2 . LEU A 1 294 ? 159.468 137.517 149.688 1.00 136.50 ? 295 LEU A CD2 1 
ATOM   2174 N N   . VAL A 1 295 ? 157.645 132.746 149.978 1.00 133.02 ? 296 VAL A N   1 
ATOM   2175 C CA  . VAL A 1 295 ? 158.204 131.546 149.349 1.00 135.66 ? 296 VAL A CA  1 
ATOM   2176 C C   . VAL A 1 295 ? 157.120 130.503 149.087 1.00 129.46 ? 296 VAL A C   1 
ATOM   2177 O O   . VAL A 1 295 ? 157.177 129.771 148.090 1.00 125.40 ? 296 VAL A O   1 
ATOM   2178 C CB  . VAL A 1 295 ? 159.372 130.993 150.207 1.00 134.35 ? 296 VAL A CB  1 
ATOM   2179 C CG1 . VAL A 1 295 ? 158.930 130.627 151.624 1.00 128.98 ? 296 VAL A CG1 1 
ATOM   2180 C CG2 . VAL A 1 295 ? 160.076 129.816 149.526 1.00 128.51 ? 296 VAL A CG2 1 
ATOM   2181 N N   . PHE A 1 296 ? 156.093 130.454 149.937 1.00 127.70 ? 297 PHE A N   1 
ATOM   2182 C CA  . PHE A 1 296 ? 155.012 129.496 149.742 1.00 133.44 ? 297 PHE A CA  1 
ATOM   2183 C C   . PHE A 1 296 ? 154.091 129.941 148.611 1.00 131.42 ? 297 PHE A C   1 
ATOM   2184 O O   . PHE A 1 296 ? 153.370 129.125 148.026 1.00 133.66 ? 297 PHE A O   1 
ATOM   2185 C CB  . PHE A 1 296 ? 154.261 129.319 151.062 1.00 134.57 ? 297 PHE A CB  1 
ATOM   2186 C CG  . PHE A 1 296 ? 153.159 128.309 151.024 1.00 133.63 ? 297 PHE A CG  1 
ATOM   2187 C CD1 . PHE A 1 296 ? 153.444 126.953 151.015 1.00 137.39 ? 297 PHE A CD1 1 
ATOM   2188 C CD2 . PHE A 1 296 ? 151.837 128.713 151.059 1.00 127.99 ? 297 PHE A CD2 1 
ATOM   2189 C CE1 . PHE A 1 296 ? 152.427 126.018 150.999 1.00 137.65 ? 297 PHE A CE1 1 
ATOM   2190 C CE2 . PHE A 1 296 ? 150.820 127.786 151.051 1.00 131.22 ? 297 PHE A CE2 1 
ATOM   2191 C CZ  . PHE A 1 296 ? 151.112 126.437 151.016 1.00 134.55 ? 297 PHE A CZ  1 
ATOM   2192 N N   . GLY A 1 297 ? 154.115 131.235 148.278 1.00 125.16 ? 298 GLY A N   1 
ATOM   2193 C CA  . GLY A 1 297 ? 153.462 131.707 147.070 1.00 126.42 ? 298 GLY A CA  1 
ATOM   2194 C C   . GLY A 1 297 ? 154.283 131.538 145.809 1.00 133.82 ? 298 GLY A C   1 
ATOM   2195 O O   . GLY A 1 297 ? 153.719 131.552 144.711 1.00 137.12 ? 298 GLY A O   1 
ATOM   2196 N N   . ASN A 1 298 ? 155.605 131.385 145.942 1.00 132.75 ? 299 ASN A N   1 
ATOM   2197 C CA  . ASN A 1 298 ? 156.454 131.181 144.771 1.00 125.40 ? 299 ASN A CA  1 
ATOM   2198 C C   . ASN A 1 298 ? 156.275 129.786 144.189 1.00 130.49 ? 299 ASN A C   1 
ATOM   2199 O O   . ASN A 1 298 ? 156.201 129.619 142.967 1.00 132.77 ? 299 ASN A O   1 
ATOM   2200 C CB  . ASN A 1 298 ? 157.921 131.409 145.136 1.00 123.41 ? 299 ASN A CB  1 
ATOM   2201 C CG  . ASN A 1 298 ? 158.191 132.817 145.607 1.00 130.40 ? 299 ASN A CG  1 
ATOM   2202 O OD1 . ASN A 1 298 ? 157.354 133.703 145.458 1.00 133.42 ? 299 ASN A OD1 1 
ATOM   2203 N ND2 . ASN A 1 298 ? 159.368 133.034 146.182 1.00 131.14 ? 299 ASN A ND2 1 
ATOM   2204 N N   . TYR A 1 299 ? 156.197 128.773 145.049 1.00 133.49 ? 300 TYR A N   1 
ATOM   2205 C CA  . TYR A 1 299 ? 156.167 127.389 144.596 1.00 129.40 ? 300 TYR A CA  1 
ATOM   2206 C C   . TYR A 1 299 ? 154.747 126.850 144.650 1.00 133.80 ? 300 TYR A C   1 
ATOM   2207 O O   . TYR A 1 299 ? 154.520 125.700 145.040 1.00 142.66 ? 300 TYR A O   1 
ATOM   2208 C CB  . TYR A 1 299 ? 157.110 126.523 145.434 1.00 132.05 ? 300 TYR A CB  1 
ATOM   2209 C CG  . TYR A 1 299 ? 158.577 126.871 145.280 1.00 135.19 ? 300 TYR A CG  1 
ATOM   2210 C CD1 . TYR A 1 299 ? 159.044 127.527 144.145 1.00 132.97 ? 300 TYR A CD1 1 
ATOM   2211 C CD2 . TYR A 1 299 ? 159.492 126.548 146.273 1.00 135.97 ? 300 TYR A CD2 1 
ATOM   2212 C CE1 . TYR A 1 299 ? 160.379 127.849 144.005 1.00 135.48 ? 300 TYR A CE1 1 
ATOM   2213 C CE2 . TYR A 1 299 ? 160.831 126.865 146.141 1.00 137.19 ? 300 TYR A CE2 1 
ATOM   2214 C CZ  . TYR A 1 299 ? 161.267 127.515 145.006 1.00 141.73 ? 300 TYR A CZ  1 
ATOM   2215 O OH  . TYR A 1 299 ? 162.599 127.831 144.872 1.00 149.01 ? 300 TYR A OH  1 
ATOM   2216 N N   . LEU A 1 300 ? 153.784 127.696 144.277 1.00 127.99 ? 301 LEU A N   1 
ATOM   2217 C CA  . LEU A 1 300 ? 152.396 127.261 144.164 1.00 131.39 ? 301 LEU A CA  1 
ATOM   2218 C C   . LEU A 1 300 ? 152.219 126.266 143.021 1.00 133.45 ? 301 LEU A C   1 
ATOM   2219 O O   . LEU A 1 300 ? 151.314 125.424 143.055 1.00 130.47 ? 301 LEU A O   1 
ATOM   2220 C CB  . LEU A 1 300 ? 151.500 128.494 144.001 1.00 133.84 ? 301 LEU A CB  1 
ATOM   2221 C CG  . LEU A 1 300 ? 149.971 128.441 143.980 1.00 134.64 ? 301 LEU A CG  1 
ATOM   2222 C CD1 . LEU A 1 300 ? 149.417 129.708 144.590 1.00 133.94 ? 301 LEU A CD1 1 
ATOM   2223 C CD2 . LEU A 1 300 ? 149.423 128.303 142.577 1.00 132.17 ? 301 LEU A CD2 1 
ATOM   2224 N N   . VAL A 1 301 ? 153.072 126.352 141.997 1.00 137.79 ? 302 VAL A N   1 
ATOM   2225 C CA  . VAL A 1 301 ? 153.050 125.373 140.912 1.00 140.91 ? 302 VAL A CA  1 
ATOM   2226 C C   . VAL A 1 301 ? 153.583 124.021 141.378 1.00 143.46 ? 302 VAL A C   1 
ATOM   2227 O O   . VAL A 1 301 ? 153.046 122.967 141.019 1.00 149.32 ? 302 VAL A O   1 
ATOM   2228 C CB  . VAL A 1 301 ? 153.830 125.906 139.695 1.00 140.89 ? 302 VAL A CB  1 
ATOM   2229 C CG1 . VAL A 1 301 ? 153.029 126.953 139.012 1.00 136.40 ? 302 VAL A CG1 1 
ATOM   2230 C CG2 . VAL A 1 301 ? 155.148 126.545 140.130 1.00 138.71 ? 302 VAL A CG2 1 
ATOM   2231 N N   . HIS A 1 302 ? 154.647 124.028 142.182 1.00 141.27 ? 303 HIS A N   1 
ATOM   2232 C CA  . HIS A 1 302 ? 155.364 122.790 142.459 1.00 143.98 ? 303 HIS A CA  1 
ATOM   2233 C C   . HIS A 1 302 ? 154.661 121.984 143.546 1.00 148.86 ? 303 HIS A C   1 
ATOM   2234 O O   . HIS A 1 302 ? 154.678 120.748 143.524 1.00 156.20 ? 303 HIS A O   1 
ATOM   2235 C CB  . HIS A 1 302 ? 156.807 123.118 142.848 1.00 141.06 ? 303 HIS A CB  1 
ATOM   2236 C CG  . HIS A 1 302 ? 157.708 121.926 142.934 1.00 151.00 ? 303 HIS A CG  1 
ATOM   2237 N ND1 . HIS A 1 302 ? 158.948 121.978 143.533 1.00 154.76 ? 303 HIS A ND1 1 
ATOM   2238 C CD2 . HIS A 1 302 ? 157.575 120.666 142.456 1.00 154.96 ? 303 HIS A CD2 1 
ATOM   2239 C CE1 . HIS A 1 302 ? 159.527 120.794 143.447 1.00 155.86 ? 303 HIS A CE1 1 
ATOM   2240 N NE2 . HIS A 1 302 ? 158.715 119.980 142.799 1.00 158.14 ? 303 HIS A NE2 1 
ATOM   2241 N N   . ILE A 1 303 ? 154.015 122.666 144.489 1.00 140.54 ? 304 ILE A N   1 
ATOM   2242 C CA  . ILE A 1 303 ? 153.349 121.976 145.589 1.00 139.36 ? 304 ILE A CA  1 
ATOM   2243 C C   . ILE A 1 303 ? 152.009 121.410 145.136 1.00 146.28 ? 304 ILE A C   1 
ATOM   2244 O O   . ILE A 1 303 ? 151.737 120.213 145.283 1.00 147.89 ? 304 ILE A O   1 
ATOM   2245 C CB  . ILE A 1 303 ? 153.184 122.923 146.791 1.00 138.32 ? 304 ILE A CB  1 
ATOM   2246 C CG1 . ILE A 1 303 ? 154.553 123.282 147.371 1.00 139.54 ? 304 ILE A CG1 1 
ATOM   2247 C CG2 . ILE A 1 303 ? 152.303 122.291 147.856 1.00 143.74 ? 304 ILE A CG2 1 
ATOM   2248 C CD1 . ILE A 1 303 ? 154.490 124.236 148.543 1.00 146.15 ? 304 ILE A CD1 1 
ATOM   2249 N N   . GLY A 1 304 ? 151.156 122.260 144.570 1.00 147.21 ? 305 GLY A N   1 
ATOM   2250 C CA  . GLY A 1 304 ? 149.826 121.847 144.166 1.00 149.52 ? 305 GLY A CA  1 
ATOM   2251 C C   . GLY A 1 304 ? 148.745 122.609 144.902 1.00 142.34 ? 305 GLY A C   1 
ATOM   2252 O O   . GLY A 1 304 ? 148.643 122.515 146.128 1.00 134.79 ? 305 GLY A O   1 
ATOM   2253 N N   . ALA A 1 305 ? 147.919 123.351 144.156 1.00 147.53 ? 306 ALA A N   1 
ATOM   2254 C CA  . ALA A 1 305 ? 146.958 124.268 144.766 1.00 147.71 ? 306 ALA A CA  1 
ATOM   2255 C C   . ALA A 1 305 ? 145.819 123.537 145.468 1.00 142.10 ? 306 ALA A C   1 
ATOM   2256 O O   . ALA A 1 305 ? 145.168 124.115 146.346 1.00 139.02 ? 306 ALA A O   1 
ATOM   2257 C CB  . ALA A 1 305 ? 146.399 125.218 143.708 1.00 144.89 ? 306 ALA A CB  1 
ATOM   2258 N N   . LYS A 1 306 ? 145.545 122.290 145.079 1.00 141.22 ? 307 LYS A N   1 
ATOM   2259 C CA  . LYS A 1 306 ? 144.553 121.491 145.792 1.00 140.37 ? 307 LYS A CA  1 
ATOM   2260 C C   . LYS A 1 306 ? 145.015 121.163 147.205 1.00 140.15 ? 307 LYS A C   1 
ATOM   2261 O O   . LYS A 1 306 ? 144.237 121.263 148.161 1.00 140.46 ? 307 LYS A O   1 
ATOM   2262 C CB  . LYS A 1 306 ? 144.258 120.208 145.017 1.00 143.92 ? 307 LYS A CB  1 
ATOM   2263 C CG  . LYS A 1 306 ? 143.254 119.307 145.701 1.00 143.40 ? 307 LYS A CG  1 
ATOM   2264 C CD  . LYS A 1 306 ? 141.879 119.937 145.738 1.00 142.88 ? 307 LYS A CD  1 
ATOM   2265 C CE  . LYS A 1 306 ? 140.868 118.961 146.296 1.00 145.11 ? 307 LYS A CE  1 
ATOM   2266 N NZ  . LYS A 1 306 ? 141.160 118.667 147.724 1.00 152.66 ? 307 LYS A NZ  1 
ATOM   2267 N N   . PHE A 1 307 ? 146.280 120.784 147.361 1.00 139.84 ? 308 PHE A N   1 
ATOM   2268 C CA  . PHE A 1 307 ? 146.818 120.448 148.672 1.00 138.68 ? 308 PHE A CA  1 
ATOM   2269 C C   . PHE A 1 307 ? 147.167 121.674 149.504 1.00 141.79 ? 308 PHE A C   1 
ATOM   2270 O O   . PHE A 1 307 ? 147.416 121.533 150.703 1.00 143.55 ? 308 PHE A O   1 
ATOM   2271 C CB  . PHE A 1 307 ? 148.058 119.551 148.537 1.00 139.75 ? 308 PHE A CB  1 
ATOM   2272 C CG  . PHE A 1 307 ? 147.746 118.078 148.394 1.00 140.98 ? 308 PHE A CG  1 
ATOM   2273 C CD1 . PHE A 1 307 ? 146.652 117.636 147.662 1.00 141.99 ? 308 PHE A CD1 1 
ATOM   2274 C CD2 . PHE A 1 307 ? 148.556 117.135 149.008 1.00 140.94 ? 308 PHE A CD2 1 
ATOM   2275 C CE1 . PHE A 1 307 ? 146.376 116.288 147.542 1.00 143.81 ? 308 PHE A CE1 1 
ATOM   2276 C CE2 . PHE A 1 307 ? 148.287 115.783 148.892 1.00 138.93 ? 308 PHE A CE2 1 
ATOM   2277 C CZ  . PHE A 1 307 ? 147.195 115.360 148.158 1.00 140.44 ? 308 PHE A CZ  1 
ATOM   2278 N N   . MET A 1 308 ? 147.197 122.861 148.898 1.00 144.27 ? 309 MET A N   1 
ATOM   2279 C CA  . MET A 1 308 ? 147.395 124.096 149.652 1.00 142.26 ? 309 MET A CA  1 
ATOM   2280 C C   . MET A 1 308 ? 146.166 124.456 150.471 1.00 137.62 ? 309 MET A C   1 
ATOM   2281 O O   . MET A 1 308 ? 146.280 124.872 151.630 1.00 140.12 ? 309 MET A O   1 
ATOM   2282 C CB  . MET A 1 308 ? 147.728 125.232 148.696 1.00 143.05 ? 309 MET A CB  1 
ATOM   2283 C CG  . MET A 1 308 ? 149.063 125.121 148.033 1.00 143.89 ? 309 MET A CG  1 
ATOM   2284 S SD  . MET A 1 308 ? 149.192 126.429 146.823 1.00 153.30 ? 309 MET A SD  1 
ATOM   2285 C CE  . MET A 1 308 ? 149.309 127.883 147.850 1.00 137.91 ? 309 MET A CE  1 
ATOM   2286 N N   . PHE A 1 309 ? 144.979 124.327 149.873 1.00 135.29 ? 310 PHE A N   1 
ATOM   2287 C CA  . PHE A 1 309 ? 143.766 124.808 150.522 1.00 138.78 ? 310 PHE A CA  1 
ATOM   2288 C C   . PHE A 1 309 ? 143.346 123.882 151.658 1.00 137.84 ? 310 PHE A C   1 
ATOM   2289 O O   . PHE A 1 309 ? 142.599 124.295 152.552 1.00 138.38 ? 310 PHE A O   1 
ATOM   2290 C CB  . PHE A 1 309 ? 142.656 124.955 149.478 1.00 141.29 ? 310 PHE A CB  1 
ATOM   2291 C CG  . PHE A 1 309 ? 141.390 125.565 150.006 1.00 139.33 ? 310 PHE A CG  1 
ATOM   2292 C CD1 . PHE A 1 309 ? 141.318 126.929 150.243 1.00 128.55 ? 310 PHE A CD1 1 
ATOM   2293 C CD2 . PHE A 1 309 ? 140.272 124.784 150.249 1.00 143.85 ? 310 PHE A CD2 1 
ATOM   2294 C CE1 . PHE A 1 309 ? 140.157 127.505 150.720 1.00 135.60 ? 310 PHE A CE1 1 
ATOM   2295 C CE2 . PHE A 1 309 ? 139.106 125.354 150.726 1.00 142.45 ? 310 PHE A CE2 1 
ATOM   2296 C CZ  . PHE A 1 309 ? 139.049 126.716 150.963 1.00 143.42 ? 310 PHE A CZ  1 
ATOM   2297 N N   . VAL A 1 310 ? 143.832 122.640 151.651 1.00 141.42 ? 311 VAL A N   1 
ATOM   2298 C CA  . VAL A 1 310 ? 143.634 121.745 152.784 1.00 145.01 ? 311 VAL A CA  1 
ATOM   2299 C C   . VAL A 1 310 ? 144.813 121.751 153.750 1.00 147.40 ? 311 VAL A C   1 
ATOM   2300 O O   . VAL A 1 310 ? 144.722 121.137 154.821 1.00 155.19 ? 311 VAL A O   1 
ATOM   2301 C CB  . VAL A 1 310 ? 143.368 120.303 152.315 1.00 145.30 ? 311 VAL A CB  1 
ATOM   2302 C CG1 . VAL A 1 310 ? 142.177 120.262 151.373 1.00 153.07 ? 311 VAL A CG1 1 
ATOM   2303 C CG2 . VAL A 1 310 ? 144.603 119.726 151.651 1.00 140.03 ? 311 VAL A CG2 1 
ATOM   2304 N N   . ALA A 1 311 ? 145.924 122.407 153.399 1.00 141.39 ? 312 ALA A N   1 
ATOM   2305 C CA  . ALA A 1 311 ? 147.033 122.516 154.342 1.00 143.76 ? 312 ALA A CA  1 
ATOM   2306 C C   . ALA A 1 311 ? 146.863 123.703 155.275 1.00 152.81 ? 312 ALA A C   1 
ATOM   2307 O O   . ALA A 1 311 ? 147.257 123.628 156.444 1.00 156.97 ? 312 ALA A O   1 
ATOM   2308 C CB  . ALA A 1 311 ? 148.365 122.632 153.606 1.00 146.21 ? 312 ALA A CB  1 
ATOM   2309 N N   . GLY A 1 312 ? 146.306 124.805 154.778 1.00 152.78 ? 313 GLY A N   1 
ATOM   2310 C CA  . GLY A 1 312 ? 146.109 125.988 155.591 1.00 153.91 ? 313 GLY A CA  1 
ATOM   2311 C C   . GLY A 1 312 ? 145.083 125.808 156.690 1.00 158.41 ? 313 GLY A C   1 
ATOM   2312 O O   . GLY A 1 312 ? 145.361 126.091 157.857 1.00 161.32 ? 313 GLY A O   1 
ATOM   2313 N N   . MET A 1 313 ? 143.897 125.314 156.334 1.00 155.39 ? 314 MET A N   1 
ATOM   2314 C CA  . MET A 1 313 ? 142.824 125.187 157.311 1.00 162.69 ? 314 MET A CA  1 
ATOM   2315 C C   . MET A 1 313 ? 143.028 124.020 158.270 1.00 168.53 ? 314 MET A C   1 
ATOM   2316 O O   . MET A 1 313 ? 142.415 124.008 159.343 1.00 173.92 ? 314 MET A O   1 
ATOM   2317 C CB  . MET A 1 313 ? 141.479 125.096 156.580 1.00 164.84 ? 314 MET A CB  1 
ATOM   2318 C CG  . MET A 1 313 ? 141.311 123.941 155.585 1.00 163.44 ? 314 MET A CG  1 
ATOM   2319 S SD  . MET A 1 313 ? 140.899 122.317 156.250 1.00 178.62 ? 314 MET A SD  1 
ATOM   2320 C CE  . MET A 1 313 ? 139.214 122.606 156.779 1.00 177.00 ? 314 MET A CE  1 
ATOM   2321 N N   . PHE A 1 314 ? 143.859 123.037 157.912 1.00 161.74 ? 315 PHE A N   1 
ATOM   2322 C CA  . PHE A 1 314 ? 144.154 121.948 158.839 1.00 164.01 ? 315 PHE A CA  1 
ATOM   2323 C C   . PHE A 1 314 ? 145.058 122.449 159.961 1.00 165.40 ? 315 PHE A C   1 
ATOM   2324 O O   . PHE A 1 314 ? 144.830 122.152 161.140 1.00 165.80 ? 315 PHE A O   1 
ATOM   2325 C CB  . PHE A 1 314 ? 144.804 120.787 158.075 1.00 166.08 ? 315 PHE A CB  1 
ATOM   2326 C CG  . PHE A 1 314 ? 145.251 119.619 158.935 1.00 174.06 ? 315 PHE A CG  1 
ATOM   2327 C CD1 . PHE A 1 314 ? 144.513 119.192 160.038 1.00 179.29 ? 315 PHE A CD1 1 
ATOM   2328 C CD2 . PHE A 1 314 ? 146.425 118.946 158.627 1.00 174.85 ? 315 PHE A CD2 1 
ATOM   2329 C CE1 . PHE A 1 314 ? 144.941 118.123 160.810 1.00 181.17 ? 315 PHE A CE1 1 
ATOM   2330 C CE2 . PHE A 1 314 ? 146.857 117.877 159.395 1.00 174.59 ? 315 PHE A CE2 1 
ATOM   2331 C CZ  . PHE A 1 314 ? 146.114 117.466 160.487 1.00 177.79 ? 315 PHE A CZ  1 
ATOM   2332 N N   . VAL A 1 315 ? 146.091 123.216 159.605 1.00 166.39 ? 316 VAL A N   1 
ATOM   2333 C CA  . VAL A 1 315 ? 146.978 123.805 160.606 1.00 170.65 ? 316 VAL A CA  1 
ATOM   2334 C C   . VAL A 1 315 ? 146.247 124.885 161.397 1.00 168.54 ? 316 VAL A C   1 
ATOM   2335 O O   . VAL A 1 315 ? 146.376 124.971 162.626 1.00 168.47 ? 316 VAL A O   1 
ATOM   2336 C CB  . VAL A 1 315 ? 148.253 124.343 159.929 1.00 168.41 ? 316 VAL A CB  1 
ATOM   2337 C CG1 . VAL A 1 315 ? 149.171 125.003 160.938 1.00 165.51 ? 316 VAL A CG1 1 
ATOM   2338 C CG2 . VAL A 1 315 ? 148.991 123.214 159.229 1.00 165.67 ? 316 VAL A CG2 1 
ATOM   2339 N N   . SER A 1 316 ? 145.440 125.704 160.712 1.00 165.46 ? 317 SER A N   1 
ATOM   2340 C CA  . SER A 1 316 ? 144.644 126.716 161.403 1.00 164.24 ? 317 SER A CA  1 
ATOM   2341 C C   . SER A 1 316 ? 143.521 126.092 162.222 1.00 168.87 ? 317 SER A C   1 
ATOM   2342 O O   . SER A 1 316 ? 142.999 126.732 163.141 1.00 174.06 ? 317 SER A O   1 
ATOM   2343 C CB  . SER A 1 316 ? 144.067 127.715 160.401 1.00 160.61 ? 317 SER A CB  1 
ATOM   2344 O OG  . SER A 1 316 ? 143.267 128.685 161.050 1.00 165.25 ? 317 SER A OG  1 
ATOM   2345 N N   . GLY A 1 317 ? 143.122 124.862 161.892 1.00 166.47 ? 318 GLY A N   1 
ATOM   2346 C CA  . GLY A 1 317 ? 142.206 124.137 162.757 1.00 170.37 ? 318 GLY A CA  1 
ATOM   2347 C C   . GLY A 1 317 ? 142.833 123.782 164.092 1.00 176.32 ? 318 GLY A C   1 
ATOM   2348 O O   . GLY A 1 317 ? 142.160 123.779 165.125 1.00 178.46 ? 318 GLY A O   1 
ATOM   2349 N N   . GLY A 1 318 ? 144.134 123.480 164.088 1.00 175.91 ? 319 GLY A N   1 
ATOM   2350 C CA  . GLY A 1 318 ? 144.819 123.175 165.334 1.00 179.18 ? 319 GLY A CA  1 
ATOM   2351 C C   . GLY A 1 318 ? 145.097 124.409 166.173 1.00 180.30 ? 319 GLY A C   1 
ATOM   2352 O O   . GLY A 1 318 ? 145.307 124.307 167.385 1.00 184.04 ? 319 GLY A O   1 
ATOM   2353 N N   . VAL A 1 319 ? 145.123 125.585 165.539 1.00 179.08 ? 320 VAL A N   1 
ATOM   2354 C CA  . VAL A 1 319 ? 145.304 126.840 166.268 1.00 178.31 ? 320 VAL A CA  1 
ATOM   2355 C C   . VAL A 1 319 ? 144.101 127.104 167.165 1.00 174.38 ? 320 VAL A C   1 
ATOM   2356 O O   . VAL A 1 319 ? 144.237 127.590 168.296 1.00 171.29 ? 320 VAL A O   1 
ATOM   2357 C CB  . VAL A 1 319 ? 145.551 127.993 165.273 1.00 177.06 ? 320 VAL A CB  1 
ATOM   2358 C CG1 . VAL A 1 319 ? 145.673 129.340 165.982 1.00 175.55 ? 320 VAL A CG1 1 
ATOM   2359 C CG2 . VAL A 1 319 ? 146.795 127.716 164.452 1.00 171.77 ? 320 VAL A CG2 1 
ATOM   2360 N N   . THR A 1 320 ? 142.908 126.740 166.690 1.00 178.71 ? 321 THR A N   1 
ATOM   2361 C CA  . THR A 1 320 ? 141.703 126.875 167.501 1.00 186.73 ? 321 THR A CA  1 
ATOM   2362 C C   . THR A 1 320 ? 141.684 125.869 168.649 1.00 188.71 ? 321 THR A C   1 
ATOM   2363 O O   . THR A 1 320 ? 140.998 126.079 169.654 1.00 189.01 ? 321 THR A O   1 
ATOM   2364 C CB  . THR A 1 320 ? 140.465 126.707 166.620 1.00 183.64 ? 321 THR A CB  1 
ATOM   2365 O OG1 . THR A 1 320 ? 140.546 125.462 165.914 1.00 179.12 ? 321 THR A OG1 1 
ATOM   2366 C CG2 . THR A 1 320 ? 140.376 127.842 165.611 1.00 174.20 ? 321 THR A CG2 1 
ATOM   2367 N N   . ILE A 1 321 ? 142.435 124.774 168.521 1.00 187.07 ? 322 ILE A N   1 
ATOM   2368 C CA  . ILE A 1 321 ? 142.431 123.750 169.562 1.00 188.68 ? 322 ILE A CA  1 
ATOM   2369 C C   . ILE A 1 321 ? 143.508 124.031 170.603 1.00 187.58 ? 322 ILE A C   1 
ATOM   2370 O O   . ILE A 1 321 ? 143.251 123.975 171.812 1.00 190.26 ? 322 ILE A O   1 
ATOM   2371 C CB  . ILE A 1 321 ? 142.597 122.354 168.932 1.00 188.91 ? 322 ILE A CB  1 
ATOM   2372 C CG1 . ILE A 1 321 ? 141.475 122.089 167.925 1.00 186.50 ? 322 ILE A CG1 1 
ATOM   2373 C CG2 . ILE A 1 321 ? 142.624 121.275 170.009 1.00 188.48 ? 322 ILE A CG2 1 
ATOM   2374 C CD1 . ILE A 1 321 ? 141.515 120.708 167.305 1.00 184.54 ? 322 ILE A CD1 1 
ATOM   2375 N N   . LEU A 1 322 ? 144.724 124.361 170.157 1.00 187.83 ? 323 LEU A N   1 
ATOM   2376 C CA  . LEU A 1 322 ? 145.854 124.460 171.080 1.00 190.63 ? 323 LEU A CA  1 
ATOM   2377 C C   . LEU A 1 322 ? 145.846 125.760 171.877 1.00 189.66 ? 323 LEU A C   1 
ATOM   2378 O O   . LEU A 1 322 ? 146.668 125.929 172.785 1.00 190.79 ? 323 LEU A O   1 
ATOM   2379 C CB  . LEU A 1 322 ? 147.181 124.313 170.327 1.00 190.59 ? 323 LEU A CB  1 
ATOM   2380 C CG  . LEU A 1 322 ? 147.782 122.926 170.043 1.00 190.64 ? 323 LEU A CG  1 
ATOM   2381 C CD1 . LEU A 1 322 ? 148.142 122.228 171.350 1.00 190.24 ? 323 LEU A CD1 1 
ATOM   2382 C CD2 . LEU A 1 322 ? 146.907 122.023 169.176 1.00 188.63 ? 323 LEU A CD2 1 
ATOM   2383 N N   . PHE A 1 323 ? 144.948 126.694 171.555 1.00 183.83 ? 324 PHE A N   1 
ATOM   2384 C CA  . PHE A 1 323 ? 144.850 127.907 172.361 1.00 182.14 ? 324 PHE A CA  1 
ATOM   2385 C C   . PHE A 1 323 ? 144.184 127.633 173.705 1.00 185.02 ? 324 PHE A C   1 
ATOM   2386 O O   . PHE A 1 323 ? 144.478 128.320 174.690 1.00 184.13 ? 324 PHE A O   1 
ATOM   2387 C CB  . PHE A 1 323 ? 144.090 128.992 171.598 1.00 177.53 ? 324 PHE A CB  1 
ATOM   2388 C CG  . PHE A 1 323 ? 144.436 130.390 172.031 1.00 173.48 ? 324 PHE A CG  1 
ATOM   2389 C CD1 . PHE A 1 323 ? 143.752 131.000 173.071 1.00 171.25 ? 324 PHE A CD1 1 
ATOM   2390 C CD2 . PHE A 1 323 ? 145.457 131.088 171.404 1.00 176.25 ? 324 PHE A CD2 1 
ATOM   2391 C CE1 . PHE A 1 323 ? 144.074 132.285 173.473 1.00 173.41 ? 324 PHE A CE1 1 
ATOM   2392 C CE2 . PHE A 1 323 ? 145.785 132.373 171.800 1.00 172.58 ? 324 PHE A CE2 1 
ATOM   2393 C CZ  . PHE A 1 323 ? 145.092 132.971 172.836 1.00 172.91 ? 324 PHE A CZ  1 
ATOM   2394 N N   . GLY A 1 324 ? 143.290 126.642 173.760 1.00 187.70 ? 325 GLY A N   1 
ATOM   2395 C CA  . GLY A 1 324 ? 142.618 126.325 175.011 1.00 189.42 ? 325 GLY A CA  1 
ATOM   2396 C C   . GLY A 1 324 ? 143.543 125.715 176.049 1.00 189.18 ? 325 GLY A C   1 
ATOM   2397 O O   . GLY A 1 324 ? 143.404 125.977 177.247 1.00 184.40 ? 325 GLY A O   1 
ATOM   2398 N N   . VAL A 1 325 ? 144.506 124.899 175.604 1.00 192.92 ? 326 VAL A N   1 
ATOM   2399 C CA  . VAL A 1 325 ? 145.377 124.169 176.522 1.00 197.81 ? 326 VAL A CA  1 
ATOM   2400 C C   . VAL A 1 325 ? 146.509 125.024 177.079 1.00 199.20 ? 326 VAL A C   1 
ATOM   2401 O O   . VAL A 1 325 ? 147.287 124.537 177.912 1.00 198.15 ? 326 VAL A O   1 
ATOM   2402 C CB  . VAL A 1 325 ? 145.959 122.914 175.837 1.00 193.13 ? 326 VAL A CB  1 
ATOM   2403 C CG1 . VAL A 1 325 ? 144.850 122.111 175.175 1.00 189.97 ? 326 VAL A CG1 1 
ATOM   2404 C CG2 . VAL A 1 325 ? 147.021 123.301 174.821 1.00 190.50 ? 326 VAL A CG2 1 
ATOM   2405 N N   . LEU A 1 326 ? 146.628 126.284 176.650 1.00 198.27 ? 327 LEU A N   1 
ATOM   2406 C CA  . LEU A 1 326 ? 147.626 127.183 177.221 1.00 195.66 ? 327 LEU A CA  1 
ATOM   2407 C C   . LEU A 1 326 ? 147.278 127.608 178.642 1.00 197.31 ? 327 LEU A C   1 
ATOM   2408 O O   . LEU A 1 326 ? 148.167 128.038 179.384 1.00 194.92 ? 327 LEU A O   1 
ATOM   2409 C CB  . LEU A 1 326 ? 147.780 128.420 176.335 1.00 195.27 ? 327 LEU A CB  1 
ATOM   2410 C CG  . LEU A 1 326 ? 148.828 128.346 175.222 1.00 197.18 ? 327 LEU A CG  1 
ATOM   2411 C CD1 . LEU A 1 326 ? 148.965 129.690 174.523 1.00 193.76 ? 327 LEU A CD1 1 
ATOM   2412 C CD2 . LEU A 1 326 ? 150.166 127.890 175.778 1.00 197.07 ? 327 LEU A CD2 1 
ATOM   2413 N N   . ASP A 1 327 ? 146.004 127.501 179.029 1.00 201.71 ? 328 ASP A N   1 
ATOM   2414 C CA  . ASP A 1 327 ? 145.580 127.877 180.374 1.00 201.21 ? 328 ASP A CA  1 
ATOM   2415 C C   . ASP A 1 327 ? 146.085 126.887 181.421 1.00 199.99 ? 328 ASP A C   1 
ATOM   2416 O O   . ASP A 1 327 ? 146.327 127.271 182.573 1.00 193.26 ? 328 ASP A O   1 
ATOM   2417 C CB  . ASP A 1 327 ? 144.051 127.987 180.402 1.00 193.87 ? 328 ASP A CB  1 
ATOM   2418 C CG  . ASP A 1 327 ? 143.492 128.125 181.802 1.00 196.97 ? 328 ASP A CG  1 
ATOM   2419 O OD1 . ASP A 1 327 ? 143.932 129.038 182.531 1.00 198.03 ? 328 ASP A OD1 1 
ATOM   2420 O OD2 . ASP A 1 327 ? 142.615 127.319 182.173 1.00 198.24 ? 328 ASP A OD2 1 
ATOM   2421 N N   . ARG A 1 328 ? 146.269 125.621 181.028 1.00 203.15 ? 329 ARG A N   1 
ATOM   2422 C CA  . ARG A 1 328 ? 146.643 124.571 181.974 1.00 204.46 ? 329 ARG A CA  1 
ATOM   2423 C C   . ARG A 1 328 ? 148.051 124.771 182.524 1.00 205.32 ? 329 ARG A C   1 
ATOM   2424 O O   . ARG A 1 328 ? 148.286 124.589 183.725 1.00 207.43 ? 329 ARG A O   1 
ATOM   2425 C CB  . ARG A 1 328 ? 146.537 123.204 181.297 1.00 204.82 ? 329 ARG A CB  1 
ATOM   2426 C CG  . ARG A 1 328 ? 145.120 122.752 180.997 1.00 204.12 ? 329 ARG A CG  1 
ATOM   2427 C CD  . ARG A 1 328 ? 144.443 122.198 182.238 1.00 205.72 ? 329 ARG A CD  1 
ATOM   2428 N NE  . ARG A 1 328 ? 143.279 121.387 181.903 1.00 208.41 ? 329 ARG A NE  1 
ATOM   2429 C CZ  . ARG A 1 328 ? 142.575 120.687 182.782 1.00 211.58 ? 329 ARG A CZ  1 
ATOM   2430 N NH1 . ARG A 1 328 ? 142.888 120.677 184.068 1.00 209.13 ? 329 ARG A NH1 1 
ATOM   2431 N NH2 . ARG A 1 328 ? 141.532 119.978 182.360 1.00 213.87 ? 329 ARG A NH2 1 
ATOM   2432 N N   . VAL A 1 329 ? 148.995 125.137 181.669 1.00 204.52 ? 330 VAL A N   1 
ATOM   2433 C CA  . VAL A 1 329 ? 150.393 125.249 182.089 1.00 206.15 ? 330 VAL A CA  1 
ATOM   2434 C C   . VAL A 1 329 ? 150.578 126.550 182.869 1.00 205.42 ? 330 VAL A C   1 
ATOM   2435 O O   . VAL A 1 329 ? 149.868 127.533 182.596 1.00 205.94 ? 330 VAL A O   1 
ATOM   2436 C CB  . VAL A 1 329 ? 151.325 125.181 180.877 1.00 205.57 ? 330 VAL A CB  1 
ATOM   2437 C CG1 . VAL A 1 329 ? 151.264 123.795 180.258 1.00 203.79 ? 330 VAL A CG1 1 
ATOM   2438 C CG2 . VAL A 1 329 ? 150.953 126.223 179.830 1.00 203.62 ? 330 VAL A CG2 1 
ATOM   2439 N N   . PRO A 1 330 ? 151.463 126.591 183.860 1.00 202.59 ? 331 PRO A N   1 
ATOM   2440 C CA  . PRO A 1 330 ? 151.760 127.848 184.551 1.00 201.70 ? 331 PRO A CA  1 
ATOM   2441 C C   . PRO A 1 330 ? 152.798 128.641 183.765 1.00 201.85 ? 331 PRO A C   1 
ATOM   2442 O O   . PRO A 1 330 ? 153.423 128.133 182.840 1.00 199.67 ? 331 PRO A O   1 
ATOM   2443 C CB  . PRO A 1 330 ? 152.301 127.397 185.914 1.00 201.53 ? 331 PRO A CB  1 
ATOM   2444 C CG  . PRO A 1 330 ? 152.406 125.892 185.856 1.00 202.80 ? 331 PRO A CG  1 
ATOM   2445 C CD  . PRO A 1 330 ? 152.208 125.463 184.443 1.00 202.48 ? 331 PRO A CD  1 
ATOM   2446 N N   . ASP A 1 331 ? 152.970 129.902 184.160 1.00 203.73 ? 332 ASP A N   1 
ATOM   2447 C CA  . ASP A 1 331 ? 153.855 130.811 183.440 1.00 202.16 ? 332 ASP A CA  1 
ATOM   2448 C C   . ASP A 1 331 ? 155.310 130.397 183.641 1.00 203.04 ? 332 ASP A C   1 
ATOM   2449 O O   . ASP A 1 331 ? 155.709 129.967 184.727 1.00 203.38 ? 332 ASP A O   1 
ATOM   2450 C CB  . ASP A 1 331 ? 153.627 132.248 183.925 1.00 203.09 ? 332 ASP A CB  1 
ATOM   2451 C CG  . ASP A 1 331 ? 154.401 133.291 183.119 1.00 202.02 ? 332 ASP A CG  1 
ATOM   2452 O OD1 . ASP A 1 331 ? 155.000 132.963 182.072 1.00 203.03 ? 332 ASP A OD1 1 
ATOM   2453 O OD2 . ASP A 1 331 ? 154.406 134.464 183.547 1.00 200.37 ? 332 ASP A OD2 1 
ATOM   2454 N N   . GLY A 1 332 ? 156.102 130.529 182.580 1.00 202.20 ? 333 GLY A N   1 
ATOM   2455 C CA  . GLY A 1 332 ? 157.485 130.119 182.602 1.00 203.71 ? 333 GLY A CA  1 
ATOM   2456 C C   . GLY A 1 332 ? 157.920 129.508 181.285 1.00 203.95 ? 333 GLY A C   1 
ATOM   2457 O O   . GLY A 1 332 ? 157.426 129.873 180.214 1.00 201.90 ? 333 GLY A O   1 
ATOM   2458 N N   . PRO A 1 333 ? 158.878 128.575 181.339 1.00 205.50 ? 334 PRO A N   1 
ATOM   2459 C CA  . PRO A 1 333 ? 159.308 127.888 180.108 1.00 201.71 ? 334 PRO A CA  1 
ATOM   2460 C C   . PRO A 1 333 ? 158.248 126.986 179.494 1.00 194.13 ? 334 PRO A C   1 
ATOM   2461 O O   . PRO A 1 333 ? 158.366 126.638 178.313 1.00 191.83 ? 334 PRO A O   1 
ATOM   2462 C CB  . PRO A 1 333 ? 160.527 127.074 180.566 1.00 203.41 ? 334 PRO A CB  1 
ATOM   2463 C CG  . PRO A 1 333 ? 160.994 127.746 181.815 1.00 204.71 ? 334 PRO A CG  1 
ATOM   2464 C CD  . PRO A 1 333 ? 159.754 128.260 182.480 1.00 204.14 ? 334 PRO A CD  1 
ATOM   2465 N N   . VAL A 1 334 ? 157.225 126.589 180.251 1.00 194.45 ? 335 VAL A N   1 
ATOM   2466 C CA  . VAL A 1 334 ? 156.198 125.708 179.707 1.00 197.42 ? 335 VAL A CA  1 
ATOM   2467 C C   . VAL A 1 334 ? 155.028 126.513 179.138 1.00 196.92 ? 335 VAL A C   1 
ATOM   2468 O O   . VAL A 1 334 ? 154.199 125.968 178.400 1.00 194.36 ? 335 VAL A O   1 
ATOM   2469 C CB  . VAL A 1 334 ? 155.780 124.707 180.806 1.00 199.62 ? 335 VAL A CB  1 
ATOM   2470 C CG1 . VAL A 1 334 ? 155.063 125.410 181.951 1.00 200.83 ? 335 VAL A CG1 1 
ATOM   2471 C CG2 . VAL A 1 334 ? 155.004 123.495 180.259 1.00 196.00 ? 335 VAL A CG2 1 
ATOM   2472 N N   . PHE A 1 335 ? 154.956 127.813 179.425 1.00 196.91 ? 336 PHE A N   1 
ATOM   2473 C CA  . PHE A 1 335 ? 153.932 128.681 178.850 1.00 194.40 ? 336 PHE A CA  1 
ATOM   2474 C C   . PHE A 1 335 ? 154.483 129.523 177.705 1.00 193.12 ? 336 PHE A C   1 
ATOM   2475 O O   . PHE A 1 335 ? 153.901 129.545 176.618 1.00 191.46 ? 336 PHE A O   1 
ATOM   2476 C CB  . PHE A 1 335 ? 153.329 129.574 179.948 1.00 197.76 ? 336 PHE A CB  1 
ATOM   2477 C CG  . PHE A 1 335 ? 152.329 130.592 179.452 1.00 198.92 ? 336 PHE A CG  1 
ATOM   2478 C CD1 . PHE A 1 335 ? 151.003 130.236 179.253 1.00 200.69 ? 336 PHE A CD1 1 
ATOM   2479 C CD2 . PHE A 1 335 ? 152.696 131.920 179.258 1.00 197.36 ? 336 PHE A CD2 1 
ATOM   2480 C CE1 . PHE A 1 335 ? 150.073 131.169 178.817 1.00 194.79 ? 336 PHE A CE1 1 
ATOM   2481 C CE2 . PHE A 1 335 ? 151.771 132.856 178.822 1.00 193.35 ? 336 PHE A CE2 1 
ATOM   2482 C CZ  . PHE A 1 335 ? 150.459 132.479 178.604 1.00 187.06 ? 336 PHE A CZ  1 
ATOM   2483 N N   . ILE A 1 336 ? 155.610 130.207 177.934 1.00 193.17 ? 337 ILE A N   1 
ATOM   2484 C CA  . ILE A 1 336 ? 156.114 131.202 176.988 1.00 193.16 ? 337 ILE A CA  1 
ATOM   2485 C C   . ILE A 1 336 ? 156.632 130.529 175.719 1.00 197.96 ? 337 ILE A C   1 
ATOM   2486 O O   . ILE A 1 336 ? 156.404 131.010 174.601 1.00 199.66 ? 337 ILE A O   1 
ATOM   2487 C CB  . ILE A 1 336 ? 157.194 132.069 177.663 1.00 195.62 ? 337 ILE A CB  1 
ATOM   2488 C CG1 . ILE A 1 336 ? 156.591 132.832 178.844 1.00 198.58 ? 337 ILE A CG1 1 
ATOM   2489 C CG2 . ILE A 1 336 ? 157.812 133.062 176.685 1.00 195.94 ? 337 ILE A CG2 1 
ATOM   2490 C CD1 . ILE A 1 336 ? 157.617 133.510 179.725 1.00 200.90 ? 337 ILE A CD1 1 
ATOM   2491 N N   . ALA A 1 337 ? 157.315 129.389 175.873 1.00 200.02 ? 338 ALA A N   1 
ATOM   2492 C CA  . ALA A 1 337 ? 157.813 128.658 174.710 1.00 197.00 ? 338 ALA A CA  1 
ATOM   2493 C C   . ALA A 1 337 ? 156.682 128.033 173.901 1.00 192.70 ? 338 ALA A C   1 
ATOM   2494 O O   . ALA A 1 337 ? 156.832 127.816 172.693 1.00 189.53 ? 338 ALA A O   1 
ATOM   2495 C CB  . ALA A 1 337 ? 158.807 127.582 175.147 1.00 195.33 ? 338 ALA A CB  1 
ATOM   2496 N N   . MET A 1 338 ? 155.551 127.730 174.542 1.00 192.37 ? 339 MET A N   1 
ATOM   2497 C CA  . MET A 1 338 ? 154.399 127.250 173.787 1.00 191.73 ? 339 MET A CA  1 
ATOM   2498 C C   . MET A 1 338 ? 153.658 128.390 173.099 1.00 192.77 ? 339 MET A C   1 
ATOM   2499 O O   . MET A 1 338 ? 152.950 128.157 172.114 1.00 193.40 ? 339 MET A O   1 
ATOM   2500 C CB  . MET A 1 338 ? 153.455 126.462 174.694 1.00 193.95 ? 339 MET A CB  1 
ATOM   2501 C CG  . MET A 1 338 ? 154.026 125.151 175.239 1.00 197.42 ? 339 MET A CG  1 
ATOM   2502 S SD  . MET A 1 338 ? 154.466 123.911 173.999 1.00 192.67 ? 339 MET A SD  1 
ATOM   2503 C CE  . MET A 1 338 ? 156.254 124.047 173.959 1.00 185.77 ? 339 MET A CE  1 
ATOM   2504 N N   . CYS A 1 339 ? 153.801 129.622 173.594 1.00 193.38 ? 340 CYS A N   1 
ATOM   2505 C CA  . CYS A 1 339 ? 153.330 130.771 172.829 1.00 193.59 ? 340 CYS A CA  1 
ATOM   2506 C C   . CYS A 1 339 ? 154.246 131.117 171.665 1.00 194.80 ? 340 CYS A C   1 
ATOM   2507 O O   . CYS A 1 339 ? 153.811 131.823 170.749 1.00 190.27 ? 340 CYS A O   1 
ATOM   2508 C CB  . CYS A 1 339 ? 153.158 132.003 173.724 1.00 197.27 ? 340 CYS A CB  1 
ATOM   2509 S SG  . CYS A 1 339 ? 152.112 131.770 175.176 1.00 209.42 ? 340 CYS A SG  1 
ATOM   2510 N N   . PHE A 1 340 ? 155.498 130.653 171.685 1.00 197.61 ? 341 PHE A N   1 
ATOM   2511 C CA  . PHE A 1 340 ? 156.363 130.803 170.518 1.00 193.13 ? 341 PHE A CA  1 
ATOM   2512 C C   . PHE A 1 340 ? 155.865 129.952 169.359 1.00 185.60 ? 341 PHE A C   1 
ATOM   2513 O O   . PHE A 1 340 ? 155.917 130.376 168.199 1.00 179.86 ? 341 PHE A O   1 
ATOM   2514 C CB  . PHE A 1 340 ? 157.806 130.425 170.868 1.00 194.04 ? 341 PHE A CB  1 
ATOM   2515 C CG  . PHE A 1 340 ? 158.496 131.392 171.800 1.00 200.26 ? 341 PHE A CG  1 
ATOM   2516 C CD1 . PHE A 1 340 ? 157.988 132.665 172.029 1.00 201.94 ? 341 PHE A CD1 1 
ATOM   2517 C CD2 . PHE A 1 340 ? 159.662 131.016 172.452 1.00 200.40 ? 341 PHE A CD2 1 
ATOM   2518 C CE1 . PHE A 1 340 ? 158.630 133.542 172.887 1.00 204.46 ? 341 PHE A CE1 1 
ATOM   2519 C CE2 . PHE A 1 340 ? 160.309 131.887 173.311 1.00 200.46 ? 341 PHE A CE2 1 
ATOM   2520 C CZ  . PHE A 1 340 ? 159.792 133.152 173.528 1.00 202.02 ? 341 PHE A CZ  1 
ATOM   2521 N N   . LEU A 1 341 ? 155.384 128.743 169.655 1.00 186.31 ? 342 LEU A N   1 
ATOM   2522 C CA  . LEU A 1 341 ? 154.938 127.834 168.607 1.00 185.45 ? 342 LEU A CA  1 
ATOM   2523 C C   . LEU A 1 341 ? 153.593 128.230 168.012 1.00 180.28 ? 342 LEU A C   1 
ATOM   2524 O O   . LEU A 1 341 ? 153.439 128.190 166.787 1.00 180.28 ? 342 LEU A O   1 
ATOM   2525 C CB  . LEU A 1 341 ? 154.863 126.404 169.144 1.00 189.91 ? 342 LEU A CB  1 
ATOM   2526 C CG  . LEU A 1 341 ? 156.168 125.797 169.663 1.00 191.91 ? 342 LEU A CG  1 
ATOM   2527 C CD1 . LEU A 1 341 ? 155.929 124.397 170.205 1.00 190.90 ? 342 LEU A CD1 1 
ATOM   2528 C CD2 . LEU A 1 341 ? 157.224 125.778 168.568 1.00 187.49 ? 342 LEU A CD2 1 
ATOM   2529 N N   . VAL A 1 342 ? 152.622 128.624 168.841 1.00 180.01 ? 343 VAL A N   1 
ATOM   2530 C CA  . VAL A 1 342 ? 151.254 128.789 168.351 1.00 179.54 ? 343 VAL A CA  1 
ATOM   2531 C C   . VAL A 1 342 ? 151.126 130.043 167.493 1.00 172.15 ? 343 VAL A C   1 
ATOM   2532 O O   . VAL A 1 342 ? 150.211 130.150 166.670 1.00 164.33 ? 343 VAL A O   1 
ATOM   2533 C CB  . VAL A 1 342 ? 150.251 128.796 169.520 1.00 183.59 ? 343 VAL A CB  1 
ATOM   2534 C CG1 . VAL A 1 342 ? 150.217 127.434 170.202 1.00 186.64 ? 343 VAL A CG1 1 
ATOM   2535 C CG2 . VAL A 1 342 ? 150.572 129.901 170.509 1.00 179.88 ? 343 VAL A CG2 1 
ATOM   2536 C CA  . ARG A 1 343 ? 151.607 132.208 166.497 1.00 165.85 ? 344 ARG A CA  1 
ATOM   2537 C C   . ARG A 1 343 ? 152.266 131.819 165.170 1.00 165.52 ? 344 ARG A C   1 
ATOM   2538 O O   . ARG A 1 343 ? 151.785 132.269 164.117 1.00 165.23 ? 344 ARG A O   1 
ATOM   2539 C CB  . ARG A 1 343 ? 152.272 133.456 167.088 1.00 163.73 ? 344 ARG A CB  1 
ATOM   2540 C CG  . ARG A 1 343 ? 151.795 134.759 166.462 1.00 168.10 ? 344 ARG A CG  1 
ATOM   2541 C CD  . ARG A 1 343 ? 150.285 134.780 166.290 1.00 165.49 ? 344 ARG A CD  1 
ATOM   2542 N NE  . ARG A 1 343 ? 149.596 135.008 167.565 1.00 168.26 ? 344 ARG A NE  1 
ATOM   2543 C CZ  . ARG A 1 343 ? 148.579 134.283 168.011 1.00 172.08 ? 344 ARG A CZ  1 
ATOM   2544 N NH1 . ARG A 1 343 ? 148.759 133.013 168.324 1.00 175.53 ? 344 ARG A NH1 1 
ATOM   2545 N NH2 . ARG A 1 343 ? 147.386 134.833 168.144 1.00 170.06 ? 344 ARG A NH2 1 
ATOM   2546 N N   . VAL A 1 344 ? 153.467 130.774 165.331 1.00 169.25 ? 345 VAL A N   1 
ATOM   2547 C CA  . VAL A 1 344 ? 153.959 130.301 164.039 1.00 167.33 ? 345 VAL A CA  1 
ATOM   2548 C C   . VAL A 1 344 ? 152.834 129.629 163.260 1.00 164.28 ? 345 VAL A C   1 
ATOM   2549 O O   . VAL A 1 344 ? 152.625 129.910 162.074 1.00 159.96 ? 345 VAL A O   1 
ATOM   2550 C CB  . VAL A 1 344 ? 155.162 129.359 164.232 1.00 171.48 ? 345 VAL A CB  1 
ATOM   2551 C CG1 . VAL A 1 344 ? 155.599 128.756 162.905 1.00 170.07 ? 345 VAL A CG1 1 
ATOM   2552 C CG2 . VAL A 1 344 ? 156.316 130.104 164.882 1.00 174.71 ? 345 VAL A CG2 1 
ATOM   2553 N N   . MET A 1 345 ? 152.072 128.753 163.922 1.00 170.24 ? 346 MET A N   1 
ATOM   2554 C CA  . MET A 1 345 ? 150.984 128.072 163.226 1.00 169.33 ? 346 MET A CA  1 
ATOM   2555 C C   . MET A 1 345 ? 149.797 128.999 162.985 1.00 164.08 ? 346 MET A C   1 
ATOM   2556 O O   . MET A 1 345 ? 148.966 128.726 162.115 1.00 161.09 ? 346 MET A O   1 
ATOM   2557 C CB  . MET A 1 345 ? 150.537 126.821 163.990 1.00 175.16 ? 346 MET A CB  1 
ATOM   2558 C CG  . MET A 1 345 ? 151.440 125.600 163.804 1.00 181.37 ? 346 MET A CG  1 
ATOM   2559 S SD  . MET A 1 345 ? 152.988 125.583 164.721 1.00 197.07 ? 346 MET A SD  1 
ATOM   2560 C CE  . MET A 1 345 ? 152.379 125.145 166.350 1.00 185.60 ? 346 MET A CE  1 
ATOM   2561 N N   . ASP A 1 346 ? 149.686 130.091 163.745 1.00 164.41 ? 347 ASP A N   1 
ATOM   2562 C CA  . ASP A 1 346 ? 148.648 131.075 163.447 1.00 161.98 ? 347 ASP A CA  1 
ATOM   2563 C C   . ASP A 1 346 ? 149.036 131.889 162.217 1.00 154.79 ? 347 ASP A C   1 
ATOM   2564 O O   . ASP A 1 346 ? 148.189 132.198 161.370 1.00 150.98 ? 347 ASP A O   1 
ATOM   2565 C CB  . ASP A 1 346 ? 148.426 131.983 164.662 1.00 169.13 ? 347 ASP A CB  1 
ATOM   2566 C CG  . ASP A 1 346 ? 147.214 132.910 164.526 1.00 168.00 ? 347 ASP A CG  1 
ATOM   2567 O OD1 . ASP A 1 346 ? 146.465 132.851 163.528 1.00 159.32 ? 347 ASP A OD1 1 
ATOM   2568 O OD2 . ASP A 1 346 ? 147.011 133.725 165.450 1.00 168.69 ? 347 ASP A OD2 1 
ATOM   2569 N N   . ALA A 1 347 ? 150.320 132.222 162.094 1.00 156.14 ? 348 ALA A N   1 
ATOM   2570 C CA  . ALA A 1 347 ? 150.775 133.054 160.986 1.00 151.28 ? 348 ALA A CA  1 
ATOM   2571 C C   . ALA A 1 347 ? 150.801 132.275 159.676 1.00 146.98 ? 348 ALA A C   1 
ATOM   2572 O O   . ALA A 1 347 ? 150.194 132.696 158.685 1.00 141.03 ? 348 ALA A O   1 
ATOM   2573 C CB  . ALA A 1 347 ? 152.158 133.625 161.298 1.00 149.46 ? 348 ALA A CB  1 
ATOM   2574 N N   . VAL A 1 348 ? 151.486 131.126 159.665 1.00 148.76 ? 349 VAL A N   1 
ATOM   2575 C CA  . VAL A 1 348 ? 151.774 130.412 158.421 1.00 143.35 ? 349 VAL A CA  1 
ATOM   2576 C C   . VAL A 1 348 ? 150.499 129.835 157.814 1.00 137.95 ? 349 VAL A C   1 
ATOM   2577 O O   . VAL A 1 348 ? 150.306 129.876 156.592 1.00 140.30 ? 349 VAL A O   1 
ATOM   2578 C CB  . VAL A 1 348 ? 152.840 129.326 158.676 1.00 149.69 ? 349 VAL A CB  1 
ATOM   2579 C CG1 . VAL A 1 348 ? 153.092 128.478 157.434 1.00 145.83 ? 349 VAL A CG1 1 
ATOM   2580 C CG2 . VAL A 1 348 ? 154.141 129.968 159.132 1.00 148.51 ? 349 VAL A CG2 1 
ATOM   2581 N N   . SER A 1 349 ? 149.592 129.332 158.656 1.00 135.61 ? 350 SER A N   1 
ATOM   2582 C CA  . SER A 1 349 ? 148.342 128.765 158.153 1.00 138.35 ? 350 SER A CA  1 
ATOM   2583 C C   . SER A 1 349 ? 147.424 129.838 157.583 1.00 134.24 ? 350 SER A C   1 
ATOM   2584 O O   . SER A 1 349 ? 146.730 129.603 156.587 1.00 128.68 ? 350 SER A O   1 
ATOM   2585 C CB  . SER A 1 349 ? 147.631 127.997 159.262 1.00 148.70 ? 350 SER A CB  1 
ATOM   2586 O OG  . SER A 1 349 ? 147.210 128.874 160.292 1.00 153.33 ? 350 SER A OG  1 
ATOM   2587 N N   . PHE A 1 350 ? 147.350 131.160 158.195 1.00 138.71 ? 351 PHE A N   1 
ATOM   2588 C CA  . PHE A 1 350 ? 146.666 132.278 157.554 1.00 136.44 ? 351 PHE A CA  1 
ATOM   2589 C C   . PHE A 1 350 ? 147.418 132.755 156.320 1.00 132.47 ? 351 PHE A C   1 
ATOM   2590 O O   . PHE A 1 350 ? 146.799 133.172 155.334 1.00 131.00 ? 351 PHE A O   1 
ATOM   2591 C CB  . PHE A 1 350 ? 146.480 133.424 158.542 1.00 143.13 ? 351 PHE A CB  1 
ATOM   2592 C CG  . PHE A 1 350 ? 145.149 134.097 158.430 1.00 147.33 ? 351 PHE A CG  1 
ATOM   2593 C CD1 . PHE A 1 350 ? 143.983 133.356 158.475 1.00 141.74 ? 351 PHE A CD1 1 
ATOM   2594 C CD2 . PHE A 1 350 ? 145.062 135.468 158.266 1.00 150.83 ? 351 PHE A CD2 1 
ATOM   2595 C CE1 . PHE A 1 350 ? 142.758 133.968 158.367 1.00 142.69 ? 351 PHE A CE1 1 
ATOM   2596 C CE2 . PHE A 1 350 ? 143.836 136.089 158.157 1.00 155.36 ? 351 PHE A CE2 1 
ATOM   2597 C CZ  . PHE A 1 350 ? 142.682 135.338 158.207 1.00 154.34 ? 351 PHE A CZ  1 
ATOM   2598 N N   . ALA A 1 351 ? 148.615 132.671 156.375 1.00 134.45 ? 352 ALA A N   1 
ATOM   2599 C CA  . ALA A 1 351 ? 149.326 133.048 155.158 1.00 133.21 ? 352 ALA A CA  1 
ATOM   2600 C C   . ALA A 1 351 ? 149.119 132.011 154.062 1.00 130.41 ? 352 ALA A C   1 
ATOM   2601 O O   . ALA A 1 351 ? 149.088 132.350 152.874 1.00 131.06 ? 352 ALA A O   1 
ATOM   2602 C CB  . ALA A 1 351 ? 150.814 133.231 155.451 1.00 132.30 ? 352 ALA A CB  1 
ATOM   2603 N N   . ALA A 1 352 ? 148.987 130.738 154.443 1.00 129.74 ? 353 ALA A N   1 
ATOM   2604 C CA  . ALA A 1 352 ? 148.688 129.699 153.464 1.00 124.36 ? 353 ALA A CA  1 
ATOM   2605 C C   . ALA A 1 352 ? 147.259 129.814 152.954 1.00 122.66 ? 353 ALA A C   1 
ATOM   2606 O O   . ALA A 1 352 ? 147.009 129.645 151.757 1.00 123.30 ? 353 ALA A O   1 
ATOM   2607 C CB  . ALA A 1 352 ? 148.922 128.316 154.068 1.00 132.19 ? 353 ALA A CB  1 
ATOM   2608 N N   . ALA A 1 353 ? 146.309 130.102 153.849 1.00 126.91 ? 354 ALA A N   1 
ATOM   2609 C CA  . ALA A 1 353 ? 144.902 130.119 153.461 1.00 123.03 ? 354 ALA A CA  1 
ATOM   2610 C C   . ALA A 1 353 ? 144.564 131.347 152.628 1.00 122.27 ? 354 ALA A C   1 
ATOM   2611 O O   . ALA A 1 353 ? 143.654 131.302 151.793 1.00 121.63 ? 354 ALA A O   1 
ATOM   2612 C CB  . ALA A 1 353 ? 144.013 130.057 154.702 1.00 122.63 ? 354 ALA A CB  1 
ATOM   2613 N N   . MET A 1 354 ? 145.212 132.451 152.884 1.00 120.93 ? 355 MET A N   1 
ATOM   2614 C CA  . MET A 1 354 ? 144.907 133.627 152.076 1.00 121.56 ? 355 MET A CA  1 
ATOM   2615 C C   . MET A 1 354 ? 145.464 133.462 150.666 1.00 120.51 ? 355 MET A C   1 
ATOM   2616 O O   . MET A 1 354 ? 144.759 133.687 149.676 1.00 122.17 ? 355 MET A O   1 
ATOM   2617 C CB  . MET A 1 354 ? 145.470 134.876 152.764 1.00 124.53 ? 355 MET A CB  1 
ATOM   2618 C CG  . MET A 1 354 ? 145.518 136.197 151.971 1.00 131.41 ? 355 MET A CG  1 
ATOM   2619 S SD  . MET A 1 354 ? 144.375 136.474 150.599 1.00 138.51 ? 355 MET A SD  1 
ATOM   2620 C CE  . MET A 1 354 ? 142.796 136.435 151.445 1.00 130.99 ? 355 MET A CE  1 
ATOM   2621 N N   . THR A 1 355 ? 146.710 132.938 150.485 1.00 117.49 ? 356 THR A N   1 
ATOM   2622 C CA  . THR A 1 355 ? 147.287 132.794 149.151 1.00 120.12 ? 356 THR A CA  1 
ATOM   2623 C C   . THR A 1 355 ? 146.596 131.692 148.359 1.00 118.64 ? 356 THR A C   1 
ATOM   2624 O O   . THR A 1 355 ? 146.479 131.783 147.131 1.00 120.61 ? 356 THR A O   1 
ATOM   2625 C CB  . THR A 1 355 ? 148.787 132.516 149.249 1.00 127.14 ? 356 THR A CB  1 
ATOM   2626 O OG1 . THR A 1 355 ? 149.008 131.354 150.058 1.00 134.39 ? 356 THR A OG1 1 
ATOM   2627 C CG2 . THR A 1 355 ? 149.514 133.706 149.855 1.00 128.20 ? 356 THR A CG2 1 
ATOM   2628 N N   . ALA A 1 356 ? 146.145 130.635 149.038 1.00 119.83 ? 357 ALA A N   1 
ATOM   2629 C CA  . ALA A 1 356 ? 145.483 129.538 148.338 1.00 121.48 ? 357 ALA A CA  1 
ATOM   2630 C C   . ALA A 1 356 ? 144.090 129.935 147.874 1.00 118.30 ? 357 ALA A C   1 
ATOM   2631 O O   . ALA A 1 356 ? 143.664 129.552 146.779 1.00 120.48 ? 357 ALA A O   1 
ATOM   2632 C CB  . ALA A 1 356 ? 145.412 128.300 149.231 1.00 127.60 ? 357 ALA A CB  1 
ATOM   2633 N N   . SER A 1 357 ? 143.364 130.701 148.693 1.00 118.15 ? 358 SER A N   1 
ATOM   2634 C CA  . SER A 1 357 ? 142.002 131.085 148.335 1.00 120.20 ? 358 SER A CA  1 
ATOM   2635 C C   . SER A 1 357 ? 141.990 132.120 147.218 1.00 121.35 ? 358 SER A C   1 
ATOM   2636 O O   . SER A 1 357 ? 141.016 132.215 146.463 1.00 125.84 ? 358 SER A O   1 
ATOM   2637 C CB  . SER A 1 357 ? 141.263 131.615 149.562 1.00 127.82 ? 358 SER A CB  1 
ATOM   2638 O OG  . SER A 1 357 ? 141.579 132.976 149.798 1.00 129.69 ? 358 SER A OG  1 
ATOM   2639 N N   . SER A 1 358 ? 143.056 132.913 147.104 1.00 122.66 ? 359 SER A N   1 
ATOM   2640 C CA  . SER A 1 358 ? 143.143 133.871 146.007 1.00 121.58 ? 359 SER A CA  1 
ATOM   2641 C C   . SER A 1 358 ? 143.436 133.173 144.686 1.00 121.64 ? 359 SER A C   1 
ATOM   2642 O O   . SER A 1 358 ? 142.928 133.578 143.634 1.00 120.69 ? 359 SER A O   1 
ATOM   2643 C CB  . SER A 1 358 ? 144.214 134.918 146.309 1.00 121.69 ? 359 SER A CB  1 
ATOM   2644 O OG  . SER A 1 358 ? 143.871 135.682 147.451 1.00 130.10 ? 359 SER A OG  1 
ATOM   2645 N N   . SER A 1 359 ? 144.261 132.125 144.718 1.00 122.17 ? 360 SER A N   1 
ATOM   2646 C CA  . SER A 1 359 ? 144.652 131.446 143.487 1.00 116.29 ? 360 SER A CA  1 
ATOM   2647 C C   . SER A 1 359 ? 143.532 130.559 142.957 1.00 113.47 ? 360 SER A C   1 
ATOM   2648 O O   . SER A 1 359 ? 143.306 130.490 141.743 1.00 119.06 ? 360 SER A O   1 
ATOM   2649 C CB  . SER A 1 359 ? 145.919 130.626 143.722 1.00 116.26 ? 360 SER A CB  1 
ATOM   2650 O OG  . SER A 1 359 ? 145.676 129.562 144.624 1.00 120.00 ? 360 SER A OG  1 
ATOM   2651 N N   . ILE A 1 360 ? 142.826 129.860 143.850 1.00 116.82 ? 361 ILE A N   1 
ATOM   2652 C CA  . ILE A 1 360 ? 141.809 128.910 143.412 1.00 119.04 ? 361 ILE A CA  1 
ATOM   2653 C C   . ILE A 1 360 ? 140.559 129.632 142.915 1.00 123.95 ? 361 ILE A C   1 
ATOM   2654 O O   . ILE A 1 360 ? 139.797 129.076 142.115 1.00 129.37 ? 361 ILE A O   1 
ATOM   2655 C CB  . ILE A 1 360 ? 141.502 127.912 144.554 1.00 116.00 ? 361 ILE A CB  1 
ATOM   2656 C CG1 . ILE A 1 360 ? 140.726 126.692 144.051 1.00 114.66 ? 361 ILE A CG1 1 
ATOM   2657 C CG2 . ILE A 1 360 ? 140.720 128.571 145.682 1.00 120.10 ? 361 ILE A CG2 1 
ATOM   2658 C CD1 . ILE A 1 360 ? 141.510 125.820 143.104 1.00 117.82 ? 361 ILE A CD1 1 
ATOM   2659 N N   . LEU A 1 361 ? 140.356 130.885 143.322 1.00 119.35 ? 362 LEU A N   1 
ATOM   2660 C CA  . LEU A 1 361 ? 139.142 131.605 142.971 1.00 118.71 ? 362 LEU A CA  1 
ATOM   2661 C C   . LEU A 1 361 ? 139.288 132.372 141.663 1.00 119.25 ? 362 LEU A C   1 
ATOM   2662 O O   . LEU A 1 361 ? 138.334 132.453 140.882 1.00 120.08 ? 362 LEU A O   1 
ATOM   2663 C CB  . LEU A 1 361 ? 138.761 132.558 144.104 1.00 121.28 ? 362 LEU A CB  1 
ATOM   2664 C CG  . LEU A 1 361 ? 137.444 133.313 143.964 1.00 131.70 ? 362 LEU A CG  1 
ATOM   2665 C CD1 . LEU A 1 361 ? 136.306 132.306 143.943 1.00 129.77 ? 362 LEU A CD1 1 
ATOM   2666 C CD2 . LEU A 1 361 ? 137.275 134.304 145.099 1.00 128.63 ? 362 LEU A CD2 1 
ATOM   2667 N N   . ALA A 1 362 ? 140.473 132.931 141.403 1.00 122.49 ? 363 ALA A N   1 
ATOM   2668 C CA  . ALA A 1 362 ? 140.687 133.672 140.165 1.00 121.89 ? 363 ALA A CA  1 
ATOM   2669 C C   . ALA A 1 362 ? 140.809 132.743 138.964 1.00 121.84 ? 363 ALA A C   1 
ATOM   2670 O O   . ALA A 1 362 ? 140.545 133.161 137.831 1.00 128.79 ? 363 ALA A O   1 
ATOM   2671 C CB  . ALA A 1 362 ? 141.928 134.553 140.287 1.00 126.97 ? 363 ALA A CB  1 
ATOM   2672 N N   . LYS A 1 363 ? 141.224 131.495 139.184 1.00 121.51 ? 364 LYS A N   1 
ATOM   2673 C CA  . LYS A 1 363 ? 141.176 130.504 138.114 1.00 126.19 ? 364 LYS A CA  1 
ATOM   2674 C C   . LYS A 1 363 ? 139.739 130.124 137.782 1.00 126.84 ? 364 LYS A C   1 
ATOM   2675 O O   . LYS A 1 363 ? 139.398 129.917 136.611 1.00 126.76 ? 364 LYS A O   1 
ATOM   2676 C CB  . LYS A 1 363 ? 141.988 129.267 138.506 1.00 124.77 ? 364 LYS A CB  1 
ATOM   2677 C CG  . LYS A 1 363 ? 142.010 128.171 137.451 1.00 121.75 ? 364 LYS A CG  1 
ATOM   2678 C CD  . LYS A 1 363 ? 142.641 128.653 136.160 1.00 126.20 ? 364 LYS A CD  1 
ATOM   2679 C CE  . LYS A 1 363 ? 144.111 128.951 136.350 1.00 130.31 ? 364 LYS A CE  1 
ATOM   2680 N NZ  . LYS A 1 363 ? 144.859 127.693 136.599 1.00 134.93 ? 364 LYS A NZ  1 
ATOM   2681 N N   . ALA A 1 364 ? 138.883 130.029 138.806 1.00 126.21 ? 365 ALA A N   1 
ATOM   2682 C CA  . ALA A 1 364 ? 137.495 129.628 138.596 1.00 128.78 ? 365 ALA A CA  1 
ATOM   2683 C C   . ALA A 1 364 ? 136.719 130.678 137.810 1.00 134.70 ? 365 ALA A C   1 
ATOM   2684 O O   . ALA A 1 364 ? 135.920 130.338 136.930 1.00 138.94 ? 365 ALA A O   1 
ATOM   2685 C CB  . ALA A 1 364 ? 136.822 129.359 139.941 1.00 129.87 ? 365 ALA A CB  1 
ATOM   2686 N N   . PHE A 1 365 ? 136.944 131.957 138.107 1.00 134.15 ? 366 PHE A N   1 
ATOM   2687 C CA  . PHE A 1 365 ? 136.289 133.044 137.385 1.00 128.65 ? 366 PHE A CA  1 
ATOM   2688 C C   . PHE A 1 365 ? 137.331 133.779 136.554 1.00 125.41 ? 366 PHE A C   1 
ATOM   2689 O O   . PHE A 1 365 ? 138.089 134.600 137.095 1.00 121.96 ? 366 PHE A O   1 
ATOM   2690 C CB  . PHE A 1 365 ? 135.593 134.011 138.350 1.00 129.18 ? 366 PHE A CB  1 
ATOM   2691 C CG  . PHE A 1 365 ? 134.280 133.506 138.911 1.00 135.60 ? 366 PHE A CG  1 
ATOM   2692 C CD1 . PHE A 1 365 ? 133.804 132.233 138.626 1.00 139.20 ? 366 PHE A CD1 1 
ATOM   2693 C CD2 . PHE A 1 365 ? 133.515 134.328 139.723 1.00 140.09 ? 366 PHE A CD2 1 
ATOM   2694 C CE1 . PHE A 1 365 ? 132.604 131.789 139.148 1.00 144.21 ? 366 PHE A CE1 1 
ATOM   2695 C CE2 . PHE A 1 365 ? 132.312 133.892 140.248 1.00 144.14 ? 366 PHE A CE2 1 
ATOM   2696 C CZ  . PHE A 1 365 ? 131.856 132.620 139.958 1.00 148.36 ? 366 PHE A CZ  1 
ATOM   2697 N N   . PRO A 1 366 ? 137.415 133.526 135.243 1.00 126.37 ? 367 PRO A N   1 
ATOM   2698 C CA  . PRO A 1 366 ? 138.483 134.134 134.436 1.00 129.29 ? 367 PRO A CA  1 
ATOM   2699 C C   . PRO A 1 366 ? 138.276 135.616 134.164 1.00 126.85 ? 367 PRO A C   1 
ATOM   2700 O O   . PRO A 1 366 ? 139.221 136.404 134.260 1.00 132.64 ? 367 PRO A O   1 
ATOM   2701 C CB  . PRO A 1 366 ? 138.451 133.322 133.131 1.00 136.23 ? 367 PRO A CB  1 
ATOM   2702 C CG  . PRO A 1 366 ? 137.440 132.220 133.340 1.00 134.08 ? 367 PRO A CG  1 
ATOM   2703 C CD  . PRO A 1 366 ? 136.544 132.651 134.445 1.00 131.77 ? 367 PRO A CD  1 
ATOM   2704 N N   . ASN A 1 367 ? 137.050 136.008 133.826 1.00 120.31 ? 368 ASN A N   1 
ATOM   2705 C CA  . ASN A 1 367 ? 136.766 137.408 133.536 1.00 120.59 ? 368 ASN A CA  1 
ATOM   2706 C C   . ASN A 1 367 ? 135.856 138.009 134.596 1.00 123.99 ? 368 ASN A C   1 
ATOM   2707 O O   . ASN A 1 367 ? 135.137 138.978 134.333 1.00 128.82 ? 368 ASN A O   1 
ATOM   2708 C CB  . ASN A 1 367 ? 136.142 137.554 132.148 1.00 124.78 ? 368 ASN A CB  1 
ATOM   2709 C CG  . ASN A 1 367 ? 137.083 137.125 131.041 1.00 131.63 ? 368 ASN A CG  1 
ATOM   2710 O OD1 . ASN A 1 367 ? 136.830 136.147 130.338 1.00 131.53 ? 368 ASN A OD1 1 
ATOM   2711 N ND2 . ASN A 1 367 ? 138.181 137.855 130.884 1.00 137.92 ? 368 ASN A ND2 1 
ATOM   2712 N N   . ASN A 1 368 ? 136.009 137.605 135.930 1.00 124.91 ? 369 ASN A N   1 
ATOM   2713 C CA  . ASN A 1 368 ? 135.098 138.099 137.003 1.00 122.77 ? 369 ASN A CA  1 
ATOM   2714 C C   . ASN A 1 368 ? 135.994 138.277 138.227 1.00 126.03 ? 369 ASN A C   1 
ATOM   2715 O O   . ASN A 1 368 ? 135.446 138.494 139.323 1.00 132.12 ? 369 ASN A O   1 
ATOM   2716 C CB  . ASN A 1 368 ? 133.785 137.372 137.264 1.00 121.66 ? 369 ASN A CB  1 
ATOM   2717 C CG  . ASN A 1 368 ? 132.854 137.457 136.080 1.00 128.77 ? 369 ASN A CG  1 
ATOM   2718 O OD1 . ASN A 1 368 ? 132.490 136.429 135.500 1.00 130.68 ? 369 ASN A OD1 1 
ATOM   2719 N ND2 . ASN A 1 368 ? 132.470 138.667 135.701 1.00 133.96 ? 369 ASN A ND2 1 
ATOM   2720 N N   . VAL A 1 369 ? 137.278 138.515 138.056 1.00 123.96 ? 370 VAL A N   1 
ATOM   2721 C CA  . VAL A 1 369 ? 138.207 138.442 139.184 1.00 124.33 ? 370 VAL A CA  1 
ATOM   2722 C C   . VAL A 1 369 ? 137.868 139.494 140.233 1.00 124.45 ? 370 VAL A C   1 
ATOM   2723 O O   . VAL A 1 369 ? 137.839 139.211 141.437 1.00 127.13 ? 370 VAL A O   1 
ATOM   2724 C CB  . VAL A 1 369 ? 139.657 138.586 138.684 1.00 130.07 ? 370 VAL A CB  1 
ATOM   2725 C CG1 . VAL A 1 369 ? 140.639 138.601 139.847 1.00 128.17 ? 370 VAL A CG1 1 
ATOM   2726 C CG2 . VAL A 1 369 ? 139.995 137.468 137.710 1.00 129.15 ? 370 VAL A CG2 1 
ATOM   2727 N N   . ALA A 1 370 ? 137.583 140.721 139.786 1.00 124.17 ? 371 ALA A N   1 
ATOM   2728 C CA  . ALA A 1 370 ? 137.329 141.822 140.713 1.00 123.61 ? 371 ALA A CA  1 
ATOM   2729 C C   . ALA A 1 370 ? 136.005 141.653 141.446 1.00 119.31 ? 371 ALA A C   1 
ATOM   2730 O O   . ALA A 1 370 ? 135.890 142.020 142.621 1.00 119.96 ? 371 ALA A O   1 
ATOM   2731 C CB  . ALA A 1 370 ? 137.348 143.153 139.963 1.00 127.54 ? 371 ALA A CB  1 
ATOM   2732 N N   . THR A 1 371 ? 134.995 141.106 140.765 1.00 121.51 ? 372 THR A N   1 
ATOM   2733 C CA  . THR A 1 371 ? 133.662 141.015 141.351 1.00 120.74 ? 372 THR A CA  1 
ATOM   2734 C C   . THR A 1 371 ? 133.600 139.942 142.432 1.00 122.79 ? 372 THR A C   1 
ATOM   2735 O O   . THR A 1 371 ? 132.919 140.116 143.449 1.00 129.12 ? 372 THR A O   1 
ATOM   2736 C CB  . THR A 1 371 ? 132.632 140.739 140.254 1.00 121.61 ? 372 THR A CB  1 
ATOM   2737 O OG1 . THR A 1 371 ? 132.847 141.642 139.163 1.00 129.43 ? 372 THR A OG1 1 
ATOM   2738 C CG2 . THR A 1 371 ? 131.216 140.939 140.775 1.00 115.82 ? 372 THR A CG2 1 
ATOM   2739 N N   . VAL A 1 372 ? 134.324 138.837 142.247 1.00 120.78 ? 373 VAL A N   1 
ATOM   2740 C CA  . VAL A 1 372 ? 134.204 137.731 143.190 1.00 123.63 ? 373 VAL A CA  1 
ATOM   2741 C C   . VAL A 1 372 ? 135.037 137.973 144.448 1.00 123.36 ? 373 VAL A C   1 
ATOM   2742 O O   . VAL A 1 372 ? 134.727 137.407 145.504 1.00 125.88 ? 373 VAL A O   1 
ATOM   2743 C CB  . VAL A 1 372 ? 134.572 136.407 142.491 1.00 131.34 ? 373 VAL A CB  1 
ATOM   2744 C CG1 . VAL A 1 372 ? 136.058 136.342 142.128 1.00 123.32 ? 373 VAL A CG1 1 
ATOM   2745 C CG2 . VAL A 1 372 ? 134.085 135.183 143.274 1.00 136.58 ? 373 VAL A CG2 1 
ATOM   2746 N N   . LEU A 1 373 ? 136.073 138.818 144.375 1.00 121.25 ? 374 LEU A N   1 
ATOM   2747 C CA  . LEU A 1 373 ? 136.776 139.242 145.583 1.00 120.13 ? 374 LEU A CA  1 
ATOM   2748 C C   . LEU A 1 373 ? 135.872 140.076 146.477 1.00 124.05 ? 374 LEU A C   1 
ATOM   2749 O O   . LEU A 1 373 ? 135.917 139.955 147.707 1.00 128.11 ? 374 LEU A O   1 
ATOM   2750 C CB  . LEU A 1 373 ? 138.016 140.053 145.224 1.00 120.40 ? 374 LEU A CB  1 
ATOM   2751 C CG  . LEU A 1 373 ? 139.175 139.411 144.477 1.00 123.69 ? 374 LEU A CG  1 
ATOM   2752 C CD1 . LEU A 1 373 ? 139.894 140.515 143.731 1.00 123.02 ? 374 LEU A CD1 1 
ATOM   2753 C CD2 . LEU A 1 373 ? 140.109 138.696 145.434 1.00 127.79 ? 374 LEU A CD2 1 
ATOM   2754 N N   . GLY A 1 374 ? 135.070 140.953 145.872 1.00 117.15 ? 375 GLY A N   1 
ATOM   2755 C CA  . GLY A 1 374 ? 134.121 141.734 146.644 1.00 118.02 ? 375 GLY A CA  1 
ATOM   2756 C C   . GLY A 1 374 ? 133.020 140.884 147.245 1.00 118.81 ? 375 GLY A C   1 
ATOM   2757 O O   . GLY A 1 374 ? 132.543 141.159 148.347 1.00 125.73 ? 375 GLY A O   1 
ATOM   2758 N N   . SER A 1 375 ? 132.599 139.842 146.526 1.00 116.73 ? 376 SER A N   1 
ATOM   2759 C CA  . SER A 1 375 ? 131.596 138.934 147.070 1.00 124.55 ? 376 SER A CA  1 
ATOM   2760 C C   . SER A 1 375 ? 132.190 138.046 148.156 1.00 124.50 ? 376 SER A C   1 
ATOM   2761 O O   . SER A 1 375 ? 131.491 137.652 149.096 1.00 129.02 ? 376 SER A O   1 
ATOM   2762 C CB  . SER A 1 375 ? 130.994 138.087 145.950 1.00 130.40 ? 376 SER A CB  1 
ATOM   2763 O OG  . SER A 1 375 ? 130.038 137.173 146.459 1.00 131.84 ? 376 SER A OG  1 
ATOM   2764 N N   . LEU A 1 376 ? 133.478 137.716 148.041 1.00 121.60 ? 377 LEU A N   1 
ATOM   2765 C CA  . LEU A 1 376 ? 134.114 136.867 149.042 1.00 123.34 ? 377 LEU A CA  1 
ATOM   2766 C C   . LEU A 1 376 ? 134.384 137.638 150.327 1.00 126.80 ? 377 LEU A C   1 
ATOM   2767 O O   . LEU A 1 376 ? 134.154 137.127 151.430 1.00 134.14 ? 377 LEU A O   1 
ATOM   2768 C CB  . LEU A 1 376 ? 135.415 136.285 148.488 1.00 131.60 ? 377 LEU A CB  1 
ATOM   2769 C CG  . LEU A 1 376 ? 136.143 135.304 149.404 1.00 138.33 ? 377 LEU A CG  1 
ATOM   2770 C CD1 . LEU A 1 376 ? 135.261 134.096 149.628 1.00 136.31 ? 377 LEU A CD1 1 
ATOM   2771 C CD2 . LEU A 1 376 ? 137.486 134.897 148.824 1.00 136.91 ? 377 LEU A CD2 1 
ATOM   2772 N N   . GLU A 1 377 ? 134.872 138.875 150.205 1.00 125.06 ? 378 GLU A N   1 
ATOM   2773 C CA  . GLU A 1 377 ? 135.218 139.658 151.384 1.00 123.77 ? 378 GLU A CA  1 
ATOM   2774 C C   . GLU A 1 377 ? 133.991 140.227 152.083 1.00 127.59 ? 378 GLU A C   1 
ATOM   2775 O O   . GLU A 1 377 ? 134.076 140.588 153.262 1.00 131.51 ? 378 GLU A O   1 
ATOM   2776 C CB  . GLU A 1 377 ? 136.181 140.785 150.999 1.00 124.22 ? 378 GLU A CB  1 
ATOM   2777 C CG  . GLU A 1 377 ? 137.059 141.310 152.138 1.00 129.25 ? 378 GLU A CG  1 
ATOM   2778 C CD  . GLU A 1 377 ? 137.873 140.231 152.841 1.00 134.75 ? 378 GLU A CD  1 
ATOM   2779 O OE1 . GLU A 1 377 ? 138.361 139.295 152.171 1.00 134.55 ? 378 GLU A OE1 1 
ATOM   2780 O OE2 . GLU A 1 377 ? 138.018 140.318 154.078 1.00 137.66 ? 378 GLU A OE2 1 
ATOM   2781 N N   . THR A 1 378 ? 132.857 140.317 151.386 1.00 125.29 ? 379 THR A N   1 
ATOM   2782 C CA  . THR A 1 378 ? 131.620 140.741 152.033 1.00 124.35 ? 379 THR A CA  1 
ATOM   2783 C C   . THR A 1 378 ? 131.117 139.675 152.997 1.00 126.93 ? 379 THR A C   1 
ATOM   2784 O O   . THR A 1 378 ? 130.666 139.989 154.104 1.00 131.88 ? 379 THR A O   1 
ATOM   2785 C CB  . THR A 1 378 ? 130.568 141.057 150.973 1.00 126.96 ? 379 THR A CB  1 
ATOM   2786 O OG1 . THR A 1 378 ? 131.070 142.090 150.121 1.00 128.20 ? 379 THR A OG1 1 
ATOM   2787 C CG2 . THR A 1 378 ? 129.263 141.531 151.604 1.00 127.23 ? 379 THR A CG2 1 
ATOM   2788 N N   . PHE A 1 379 ? 131.216 138.402 152.603 1.00 126.72 ? 380 PHE A N   1 
ATOM   2789 C CA  . PHE A 1 379 ? 130.773 137.316 153.467 1.00 132.68 ? 380 PHE A CA  1 
ATOM   2790 C C   . PHE A 1 379 ? 131.710 137.111 154.652 1.00 135.90 ? 380 PHE A C   1 
ATOM   2791 O O   . PHE A 1 379 ? 131.297 136.528 155.660 1.00 141.61 ? 380 PHE A O   1 
ATOM   2792 C CB  . PHE A 1 379 ? 130.640 136.027 152.655 1.00 136.29 ? 380 PHE A CB  1 
ATOM   2793 C CG  . PHE A 1 379 ? 129.909 134.930 153.372 1.00 144.72 ? 380 PHE A CG  1 
ATOM   2794 C CD1 . PHE A 1 379 ? 128.527 134.964 153.484 1.00 147.34 ? 380 PHE A CD1 1 
ATOM   2795 C CD2 . PHE A 1 379 ? 130.597 133.863 153.925 1.00 144.74 ? 380 PHE A CD2 1 
ATOM   2796 C CE1 . PHE A 1 379 ? 127.843 133.954 154.141 1.00 147.05 ? 380 PHE A CE1 1 
ATOM   2797 C CE2 . PHE A 1 379 ? 129.921 132.848 154.582 1.00 147.86 ? 380 PHE A CE2 1 
ATOM   2798 C CZ  . PHE A 1 379 ? 128.543 132.895 154.691 1.00 150.50 ? 380 PHE A CZ  1 
ATOM   2799 N N   . SER A 1 380 ? 132.956 137.582 154.556 1.00 130.34 ? 381 SER A N   1 
ATOM   2800 C CA  . SER A 1 380 ? 133.806 137.674 155.736 1.00 134.08 ? 381 SER A CA  1 
ATOM   2801 C C   . SER A 1 380 ? 133.409 138.842 156.628 1.00 132.10 ? 381 SER A C   1 
ATOM   2802 O O   . SER A 1 380 ? 133.749 138.845 157.816 1.00 133.74 ? 381 SER A O   1 
ATOM   2803 C CB  . SER A 1 380 ? 135.272 137.810 155.327 1.00 139.44 ? 381 SER A CB  1 
ATOM   2804 O OG  . SER A 1 380 ? 135.503 139.042 154.670 1.00 131.94 ? 381 SER A OG  1 
ATOM   2805 N N   . GLY A 1 381 ? 132.701 139.833 156.082 1.00 130.79 ? 382 GLY A N   1 
ATOM   2806 C CA  . GLY A 1 381 ? 132.164 140.897 156.910 1.00 132.80 ? 382 GLY A CA  1 
ATOM   2807 C C   . GLY A 1 381 ? 130.917 140.487 157.667 1.00 137.19 ? 382 GLY A C   1 
ATOM   2808 O O   . GLY A 1 381 ? 130.469 141.204 158.565 1.00 141.54 ? 382 GLY A O   1 
ATOM   2809 N N   . LEU A 1 382 ? 130.327 139.346 157.305 1.00 134.53 ? 383 LEU A N   1 
ATOM   2810 C CA  . LEU A 1 382 ? 129.254 138.783 158.117 1.00 135.56 ? 383 LEU A CA  1 
ATOM   2811 C C   . LEU A 1 382 ? 129.806 137.991 159.293 1.00 141.21 ? 383 LEU A C   1 
ATOM   2812 O O   . LEU A 1 382 ? 129.046 137.612 160.192 1.00 146.35 ? 383 LEU A O   1 
ATOM   2813 C CB  . LEU A 1 382 ? 128.341 137.893 157.269 1.00 137.73 ? 383 LEU A CB  1 
ATOM   2814 C CG  . LEU A 1 382 ? 127.180 138.472 156.445 1.00 144.18 ? 383 LEU A CG  1 
ATOM   2815 C CD1 . LEU A 1 382 ? 126.145 139.109 157.364 1.00 144.31 ? 383 LEU A CD1 1 
ATOM   2816 C CD2 . LEU A 1 382 ? 127.613 139.447 155.353 1.00 142.93 ? 383 LEU A CD2 1 
ATOM   2817 N N   . GLY A 1 383 ? 131.113 137.714 159.290 1.00 144.68 ? 384 GLY A N   1 
ATOM   2818 C CA  . GLY A 1 383 ? 131.710 136.950 160.375 1.00 148.09 ? 384 GLY A CA  1 
ATOM   2819 C C   . GLY A 1 383 ? 131.725 137.702 161.693 1.00 147.54 ? 384 GLY A C   1 
ATOM   2820 O O   . GLY A 1 383 ? 131.414 137.139 162.746 1.00 151.93 ? 384 GLY A O   1 
ATOM   2821 N N   . LEU A 1 384 ? 132.082 138.987 161.654 1.00 142.48 ? 385 LEU A N   1 
ATOM   2822 C CA  . LEU A 1 384 ? 132.100 139.775 162.880 1.00 145.67 ? 385 LEU A CA  1 
ATOM   2823 C C   . LEU A 1 384 ? 130.718 140.288 163.262 1.00 145.84 ? 385 LEU A C   1 
ATOM   2824 O O   . LEU A 1 384 ? 130.550 140.802 164.374 1.00 148.24 ? 385 LEU A O   1 
ATOM   2825 C CB  . LEU A 1 384 ? 133.087 140.946 162.776 1.00 148.50 ? 385 LEU A CB  1 
ATOM   2826 C CG  . LEU A 1 384 ? 132.863 142.206 161.933 1.00 149.97 ? 385 LEU A CG  1 
ATOM   2827 C CD1 . LEU A 1 384 ? 133.848 143.269 162.382 1.00 147.06 ? 385 LEU A CD1 1 
ATOM   2828 C CD2 . LEU A 1 384 ? 133.061 141.946 160.454 1.00 148.72 ? 385 LEU A CD2 1 
ATOM   2829 N N   . ILE A 1 385 ? 129.733 140.168 162.370 1.00 143.21 ? 386 ILE A N   1 
ATOM   2830 C CA  . ILE A 1 385 ? 128.341 140.353 162.770 1.00 145.62 ? 386 ILE A CA  1 
ATOM   2831 C C   . ILE A 1 385 ? 127.921 139.235 163.717 1.00 145.19 ? 386 ILE A C   1 
ATOM   2832 O O   . ILE A 1 385 ? 127.176 139.458 164.680 1.00 148.56 ? 386 ILE A O   1 
ATOM   2833 C CB  . ILE A 1 385 ? 127.441 140.432 161.521 1.00 150.98 ? 386 ILE A CB  1 
ATOM   2834 C CG1 . ILE A 1 385 ? 127.884 141.587 160.622 1.00 149.25 ? 386 ILE A CG1 1 
ATOM   2835 C CG2 . ILE A 1 385 ? 125.975 140.620 161.897 1.00 152.81 ? 386 ILE A CG2 1 
ATOM   2836 C CD1 . ILE A 1 385 ? 127.800 142.946 161.285 1.00 148.01 ? 386 ILE A CD1 1 
ATOM   2837 N N   . LEU A 1 386 ? 128.442 138.028 163.494 1.00 145.00 ? 387 LEU A N   1 
ATOM   2838 C CA  . LEU A 1 386 ? 128.211 136.868 164.345 1.00 150.23 ? 387 LEU A CA  1 
ATOM   2839 C C   . LEU A 1 386 ? 129.158 136.814 165.550 1.00 153.68 ? 387 LEU A C   1 
ATOM   2840 O O   . LEU A 1 386 ? 129.389 135.729 166.096 1.00 153.32 ? 387 LEU A O   1 
ATOM   2841 C CB  . LEU A 1 386 ? 128.339 135.586 163.520 1.00 155.34 ? 387 LEU A CB  1 
ATOM   2842 C CG  . LEU A 1 386 ? 127.159 135.236 162.610 1.00 156.85 ? 387 LEU A CG  1 
ATOM   2843 C CD1 . LEU A 1 386 ? 127.475 134.007 161.769 1.00 157.55 ? 387 LEU A CD1 1 
ATOM   2844 C CD2 . LEU A 1 386 ? 125.886 135.025 163.414 1.00 156.51 ? 387 LEU A CD2 1 
ATOM   2845 N N   . GLY A 1 387 ? 129.717 137.955 165.951 1.00 154.30 ? 388 GLY A N   1 
ATOM   2846 C CA  . GLY A 1 387 ? 130.515 138.079 167.150 1.00 153.44 ? 388 GLY A CA  1 
ATOM   2847 C C   . GLY A 1 387 ? 129.798 137.742 168.448 1.00 162.28 ? 388 GLY A C   1 
ATOM   2848 O O   . GLY A 1 387 ? 130.132 136.756 169.105 1.00 167.34 ? 388 GLY A O   1 
ATOM   2849 N N   . PRO A 1 388 ? 128.810 138.543 168.855 1.00 159.32 ? 389 PRO A N   1 
ATOM   2850 C CA  . PRO A 1 388 ? 128.094 138.271 170.129 1.00 161.64 ? 389 PRO A CA  1 
ATOM   2851 C C   . PRO A 1 388 ? 127.217 137.021 170.140 1.00 165.99 ? 389 PRO A C   1 
ATOM   2852 O O   . PRO A 1 388 ? 126.655 136.707 171.201 1.00 168.53 ? 389 PRO A O   1 
ATOM   2853 C CB  . PRO A 1 388 ? 127.256 139.542 170.336 1.00 159.16 ? 389 PRO A CB  1 
ATOM   2854 C CG  . PRO A 1 388 ? 127.096 140.134 168.993 1.00 154.96 ? 389 PRO A CG  1 
ATOM   2855 C CD  . PRO A 1 388 ? 128.367 139.818 168.253 1.00 152.81 ? 389 PRO A CD  1 
ATOM   2856 N N   . PRO A 1 389 ? 127.042 136.269 169.034 1.00 164.48 ? 390 PRO A N   1 
ATOM   2857 C CA  . PRO A 1 389 ? 126.693 134.847 169.218 1.00 166.48 ? 390 PRO A CA  1 
ATOM   2858 C C   . PRO A 1 389 ? 127.711 133.995 169.974 1.00 172.72 ? 390 PRO A C   1 
ATOM   2859 O O   . PRO A 1 389 ? 127.340 132.906 170.432 1.00 174.11 ? 390 PRO A O   1 
ATOM   2860 C CB  . PRO A 1 389 ? 126.510 134.358 167.779 1.00 164.46 ? 390 PRO A CB  1 
ATOM   2861 C CG  . PRO A 1 389 ? 125.875 135.496 167.132 1.00 161.72 ? 390 PRO A CG  1 
ATOM   2862 C CD  . PRO A 1 389 ? 126.439 136.742 167.765 1.00 160.00 ? 390 PRO A CD  1 
ATOM   2863 N N   . VAL A 1 390 ? 128.976 134.417 170.093 1.00 174.17 ? 391 VAL A N   1 
ATOM   2864 C CA  . VAL A 1 390 ? 129.893 133.746 171.016 1.00 179.41 ? 391 VAL A CA  1 
ATOM   2865 C C   . VAL A 1 390 ? 129.402 133.911 172.450 1.00 186.05 ? 391 VAL A C   1 
ATOM   2866 O O   . VAL A 1 390 ? 129.395 132.956 173.239 1.00 189.14 ? 391 VAL A O   1 
ATOM   2867 C CB  . VAL A 1 390 ? 131.331 134.277 170.836 1.00 175.33 ? 391 VAL A CB  1 
ATOM   2868 C CG1 . VAL A 1 390 ? 132.257 133.767 171.932 1.00 180.01 ? 391 VAL A CG1 1 
ATOM   2869 C CG2 . VAL A 1 390 ? 131.871 133.899 169.468 1.00 169.56 ? 391 VAL A CG2 1 
ATOM   2870 N N   . GLY A 1 391 ? 128.928 135.109 172.791 1.00 186.56 ? 392 GLY A N   1 
ATOM   2871 C CA  . GLY A 1 391 ? 128.349 135.363 174.097 1.00 190.56 ? 392 GLY A CA  1 
ATOM   2872 C C   . GLY A 1 391 ? 126.940 134.834 174.278 1.00 190.65 ? 392 GLY A C   1 
ATOM   2873 O O   . GLY A 1 391 ? 126.385 134.976 175.373 1.00 191.39 ? 392 GLY A O   1 
ATOM   2874 N N   . GLY A 1 392 ? 126.352 134.243 173.238 1.00 187.33 ? 393 GLY A N   1 
ATOM   2875 C CA  . GLY A 1 392 ? 125.019 133.678 173.320 1.00 186.21 ? 393 GLY A CA  1 
ATOM   2876 C C   . GLY A 1 392 ? 124.916 132.482 174.243 1.00 193.84 ? 393 GLY A C   1 
ATOM   2877 O O   . GLY A 1 392 ? 124.243 132.550 175.276 1.00 197.74 ? 393 GLY A O   1 
ATOM   2878 N N   . PHE A 1 393 ? 125.574 131.380 173.888 1.00 195.98 ? 394 PHE A N   1 
ATOM   2879 C CA  . PHE A 1 393 ? 125.530 130.168 174.697 1.00 198.90 ? 394 PHE A CA  1 
ATOM   2880 C C   . PHE A 1 393 ? 126.912 129.629 175.031 1.00 199.12 ? 394 PHE A C   1 
ATOM   2881 O O   . PHE A 1 393 ? 127.095 129.045 176.106 1.00 199.22 ? 394 PHE A O   1 
ATOM   2882 C CB  . PHE A 1 393 ? 124.700 129.089 173.979 1.00 198.09 ? 394 PHE A CB  1 
ATOM   2883 C CG  . PHE A 1 393 ? 124.552 127.813 174.761 1.00 197.41 ? 394 PHE A CG  1 
ATOM   2884 C CD1 . PHE A 1 393 ? 123.691 127.748 175.847 1.00 196.31 ? 394 PHE A CD1 1 
ATOM   2885 C CD2 . PHE A 1 393 ? 125.260 126.675 174.402 1.00 197.66 ? 394 PHE A CD2 1 
ATOM   2886 C CE1 . PHE A 1 393 ? 123.547 126.577 176.569 1.00 194.98 ? 394 PHE A CE1 1 
ATOM   2887 C CE2 . PHE A 1 393 ? 125.120 125.497 175.119 1.00 200.33 ? 394 PHE A CE2 1 
ATOM   2888 C CZ  . PHE A 1 393 ? 124.262 125.450 176.204 1.00 198.52 ? 394 PHE A CZ  1 
ATOM   2889 N N   . LEU A 1 394 ? 127.890 129.803 174.134 1.00 199.38 ? 395 LEU A N   1 
ATOM   2890 C CA  . LEU A 1 394 ? 129.215 129.222 174.343 1.00 199.91 ? 395 LEU A CA  1 
ATOM   2891 C C   . LEU A 1 394 ? 129.961 129.913 175.477 1.00 200.42 ? 395 LEU A C   1 
ATOM   2892 O O   . LEU A 1 394 ? 130.687 129.263 176.239 1.00 200.43 ? 395 LEU A O   1 
ATOM   2893 C CB  . LEU A 1 394 ? 130.028 129.288 173.050 1.00 197.84 ? 395 LEU A CB  1 
ATOM   2894 C CG  . LEU A 1 394 ? 129.559 128.400 171.896 1.00 199.50 ? 395 LEU A CG  1 
ATOM   2895 C CD1 . LEU A 1 394 ? 130.533 128.481 170.732 1.00 198.75 ? 395 LEU A CD1 1 
ATOM   2896 C CD2 . LEU A 1 394 ? 129.396 126.960 172.359 1.00 194.59 ? 395 LEU A CD2 1 
ATOM   2897 N N   . TYR A 1 395 ? 129.804 131.231 175.601 1.00 200.85 ? 396 TYR A N   1 
ATOM   2898 C CA  . TYR A 1 395 ? 130.419 131.943 176.716 1.00 205.56 ? 396 TYR A CA  1 
ATOM   2899 C C   . TYR A 1 395 ? 129.692 131.673 178.027 1.00 207.14 ? 396 TYR A C   1 
ATOM   2900 O O   . TYR A 1 395 ? 130.324 131.644 179.090 1.00 205.87 ? 396 TYR A O   1 
ATOM   2901 C CB  . TYR A 1 395 ? 130.457 133.442 176.421 1.00 200.85 ? 396 TYR A CB  1 
ATOM   2902 C CG  . TYR A 1 395 ? 131.097 134.273 177.507 1.00 200.34 ? 396 TYR A CG  1 
ATOM   2903 C CD1 . TYR A 1 395 ? 132.476 134.291 177.672 1.00 202.01 ? 396 TYR A CD1 1 
ATOM   2904 C CD2 . TYR A 1 395 ? 130.320 135.049 178.362 1.00 199.77 ? 396 TYR A CD2 1 
ATOM   2905 C CE1 . TYR A 1 395 ? 133.067 135.053 178.665 1.00 207.51 ? 396 TYR A CE1 1 
ATOM   2906 C CE2 . TYR A 1 395 ? 130.899 135.813 179.357 1.00 204.87 ? 396 TYR A CE2 1 
ATOM   2907 C CZ  . TYR A 1 395 ? 132.273 135.811 179.504 1.00 212.79 ? 396 TYR A CZ  1 
ATOM   2908 O OH  . TYR A 1 395 ? 132.856 136.571 180.492 1.00 218.73 ? 396 TYR A OH  1 
ATOM   2909 N N   . GLN A 1 396 ? 128.374 131.472 177.975 1.00 204.86 ? 397 GLN A N   1 
ATOM   2910 C CA  . GLN A 1 396 ? 127.600 131.303 179.198 1.00 205.06 ? 397 GLN A CA  1 
ATOM   2911 C C   . GLN A 1 396 ? 127.668 129.880 179.738 1.00 205.48 ? 397 GLN A C   1 
ATOM   2912 O O   . GLN A 1 396 ? 127.290 129.643 180.891 1.00 205.85 ? 397 GLN A O   1 
ATOM   2913 C CB  . GLN A 1 396 ? 126.140 131.702 178.953 1.00 203.22 ? 397 GLN A CB  1 
ATOM   2914 C CG  . GLN A 1 396 ? 125.809 133.209 179.051 1.00 204.93 ? 397 GLN A CG  1 
ATOM   2915 C CD  . GLN A 1 396 ? 126.114 133.891 180.394 1.00 208.08 ? 397 GLN A CD  1 
ATOM   2916 O OE1 . GLN A 1 396 ? 126.386 133.250 181.412 1.00 209.05 ? 397 GLN A OE1 1 
ATOM   2917 N NE2 . GLN A 1 396 ? 126.063 135.218 180.386 1.00 209.93 ? 397 GLN A NE2 1 
ATOM   2918 N N   . SER A 1 397 ? 128.141 128.927 178.936 1.00 204.25 ? 398 SER A N   1 
ATOM   2919 C CA  . SER A 1 397 ? 128.198 127.533 179.366 1.00 200.96 ? 398 SER A CA  1 
ATOM   2920 C C   . SER A 1 397 ? 129.502 127.217 180.093 1.00 202.99 ? 398 SER A C   1 
ATOM   2921 O O   . SER A 1 397 ? 129.489 126.798 181.254 1.00 201.92 ? 398 SER A O   1 
ATOM   2922 C CB  . SER A 1 397 ? 128.026 126.605 178.158 1.00 196.02 ? 398 SER A CB  1 
ATOM   2923 O OG  . SER A 1 397 ? 126.888 126.969 177.399 1.00 197.54 ? 398 SER A OG  1 
ATOM   2924 N N   . PHE A 1 398 ? 130.634 127.419 179.419 1.00 206.91 ? 399 PHE A N   1 
ATOM   2925 C CA  . PHE A 1 398 ? 131.929 127.013 179.946 1.00 207.42 ? 399 PHE A CA  1 
ATOM   2926 C C   . PHE A 1 398 ? 132.826 128.181 180.329 1.00 205.20 ? 399 PHE A C   1 
ATOM   2927 O O   . PHE A 1 398 ? 133.780 127.983 181.088 1.00 201.95 ? 399 PHE A O   1 
ATOM   2928 C CB  . PHE A 1 398 ? 132.655 126.135 178.920 1.00 202.66 ? 399 PHE A CB  1 
ATOM   2929 C CG  . PHE A 1 398 ? 131.780 125.083 178.306 1.00 196.28 ? 399 PHE A CG  1 
ATOM   2930 C CD1 . PHE A 1 398 ? 131.384 123.979 179.044 1.00 193.69 ? 399 PHE A CD1 1 
ATOM   2931 C CD2 . PHE A 1 398 ? 131.335 125.208 176.998 1.00 191.62 ? 399 PHE A CD2 1 
ATOM   2932 C CE1 . PHE A 1 398 ? 130.574 123.008 178.486 1.00 192.67 ? 399 PHE A CE1 1 
ATOM   2933 C CE2 . PHE A 1 398 ? 130.522 124.242 176.432 1.00 189.29 ? 399 PHE A CE2 1 
ATOM   2934 C CZ  . PHE A 1 398 ? 130.142 123.141 177.178 1.00 191.22 ? 399 PHE A CZ  1 
ATOM   2935 N N   . GLY A 1 399 ? 132.548 129.382 179.830 1.00 203.43 ? 400 GLY A N   1 
ATOM   2936 C CA  . GLY A 1 399 ? 133.383 130.524 180.137 1.00 197.92 ? 400 GLY A CA  1 
ATOM   2937 C C   . GLY A 1 399 ? 134.551 130.666 179.184 1.00 193.49 ? 400 GLY A C   1 
ATOM   2938 O O   . GLY A 1 399 ? 134.356 130.903 177.989 1.00 192.69 ? 400 GLY A O   1 
ATOM   2939 N N   . TYR A 1 400 ? 135.769 130.525 179.700 1.00 192.80 ? 401 TYR A N   1 
ATOM   2940 C CA  . TYR A 1 400 ? 136.974 130.699 178.902 1.00 200.68 ? 401 TYR A CA  1 
ATOM   2941 C C   . TYR A 1 400 ? 137.818 129.436 178.794 1.00 200.77 ? 401 TYR A C   1 
ATOM   2942 O O   . TYR A 1 400 ? 138.836 129.452 178.094 1.00 196.27 ? 401 TYR A O   1 
ATOM   2943 C CB  . TYR A 1 400 ? 137.823 131.840 179.477 1.00 202.98 ? 401 TYR A CB  1 
ATOM   2944 C CG  . TYR A 1 400 ? 138.753 131.425 180.598 1.00 205.75 ? 401 TYR A CG  1 
ATOM   2945 C CD1 . TYR A 1 400 ? 138.255 131.093 181.853 1.00 206.31 ? 401 TYR A CD1 1 
ATOM   2946 C CD2 . TYR A 1 400 ? 140.132 131.381 180.405 1.00 205.62 ? 401 TYR A CD2 1 
ATOM   2947 C CE1 . TYR A 1 400 ? 139.102 130.716 182.883 1.00 207.80 ? 401 TYR A CE1 1 
ATOM   2948 C CE2 . TYR A 1 400 ? 140.986 131.005 181.428 1.00 206.73 ? 401 TYR A CE2 1 
ATOM   2949 C CZ  . TYR A 1 400 ? 140.465 130.675 182.664 1.00 208.97 ? 401 TYR A CZ  1 
ATOM   2950 O OH  . TYR A 1 400 ? 141.311 130.303 183.684 1.00 210.94 ? 401 TYR A OH  1 
ATOM   2951 N N   . GLU A 1 401 ? 137.427 128.344 179.455 1.00 201.56 ? 402 GLU A N   1 
ATOM   2952 C CA  . GLU A 1 401 ? 138.295 127.171 179.497 1.00 198.33 ? 402 GLU A CA  1 
ATOM   2953 C C   . GLU A 1 401 ? 138.221 126.373 178.200 1.00 198.48 ? 402 GLU A C   1 
ATOM   2954 O O   . GLU A 1 401 ? 139.202 126.298 177.452 1.00 195.46 ? 402 GLU A O   1 
ATOM   2955 C CB  . GLU A 1 401 ? 137.926 126.287 180.692 1.00 201.45 ? 402 GLU A CB  1 
ATOM   2956 C CG  . GLU A 1 401 ? 138.279 126.889 182.041 1.00 204.83 ? 402 GLU A CG  1 
ATOM   2957 C CD  . GLU A 1 401 ? 139.571 126.332 182.603 1.00 205.49 ? 402 GLU A CD  1 
ATOM   2958 O OE1 . GLU A 1 401 ? 140.247 125.563 181.888 1.00 204.56 ? 402 GLU A OE1 1 
ATOM   2959 O OE2 . GLU A 1 401 ? 139.912 126.663 183.758 1.00 205.40 ? 402 GLU A OE2 1 
ATOM   2960 N N   . VAL A 1 402 ? 137.067 125.775 177.909 1.00 205.03 ? 403 VAL A N   1 
ATOM   2961 C CA  . VAL A 1 402 ? 136.873 125.081 176.633 1.00 203.46 ? 403 VAL A CA  1 
ATOM   2962 C C   . VAL A 1 402 ? 135.590 125.596 175.978 1.00 198.46 ? 403 VAL A C   1 
ATOM   2963 O O   . VAL A 1 402 ? 134.512 125.020 176.194 1.00 196.99 ? 403 VAL A O   1 
ATOM   2964 C CB  . VAL A 1 402 ? 136.833 123.545 176.811 1.00 202.95 ? 403 VAL A CB  1 
ATOM   2965 C CG1 . VAL A 1 402 ? 136.693 122.821 175.461 1.00 199.28 ? 403 VAL A CG1 1 
ATOM   2966 C CG2 . VAL A 1 402 ? 138.065 123.010 177.545 1.00 202.84 ? 403 VAL A CG2 1 
ATOM   2967 N N   . PRO A 1 403 ? 135.616 126.735 175.267 1.00 196.15 ? 404 PRO A N   1 
ATOM   2968 C CA  . PRO A 1 403 ? 134.633 126.930 174.193 1.00 192.59 ? 404 PRO A CA  1 
ATOM   2969 C C   . PRO A 1 403 ? 135.229 126.660 172.819 1.00 190.90 ? 404 PRO A C   1 
ATOM   2970 O O   . PRO A 1 403 ? 134.508 126.602 171.819 1.00 191.70 ? 404 PRO A O   1 
ATOM   2971 C CB  . PRO A 1 403 ? 134.218 128.401 174.340 1.00 193.90 ? 404 PRO A CB  1 
ATOM   2972 C CG  . PRO A 1 403 ? 135.115 128.995 175.390 1.00 195.60 ? 404 PRO A CG  1 
ATOM   2973 C CD  . PRO A 1 403 ? 136.197 128.018 175.697 1.00 198.48 ? 404 PRO A CD  1 
ATOM   2974 N N   . PHE A 1 404 ? 136.551 126.482 172.766 1.00 192.01 ? 405 PHE A N   1 
ATOM   2975 C CA  . PHE A 1 404 ? 137.270 126.544 171.499 1.00 193.64 ? 405 PHE A CA  1 
ATOM   2976 C C   . PHE A 1 404 ? 137.341 125.188 170.810 1.00 193.40 ? 405 PHE A C   1 
ATOM   2977 O O   . PHE A 1 404 ? 137.356 125.121 169.576 1.00 191.31 ? 405 PHE A O   1 
ATOM   2978 C CB  . PHE A 1 404 ? 138.681 127.089 171.725 1.00 194.99 ? 405 PHE A CB  1 
ATOM   2979 C CG  . PHE A 1 404 ? 138.720 128.512 172.207 1.00 191.37 ? 405 PHE A CG  1 
ATOM   2980 C CD1 . PHE A 1 404 ? 138.556 129.564 171.320 1.00 186.66 ? 405 PHE A CD1 1 
ATOM   2981 C CD2 . PHE A 1 404 ? 138.949 128.795 173.544 1.00 185.04 ? 405 PHE A CD2 1 
ATOM   2982 C CE1 . PHE A 1 404 ? 138.598 130.874 171.762 1.00 178.27 ? 405 PHE A CE1 1 
ATOM   2983 C CE2 . PHE A 1 404 ? 138.992 130.101 173.993 1.00 178.22 ? 405 PHE A CE2 1 
ATOM   2984 C CZ  . PHE A 1 404 ? 138.817 131.142 173.100 1.00 178.38 ? 405 PHE A CZ  1 
ATOM   2985 N N   . ILE A 1 405 ? 137.422 124.105 171.587 1.00 195.82 ? 406 ILE A N   1 
ATOM   2986 C CA  . ILE A 1 405 ? 137.559 122.771 171.007 1.00 201.14 ? 406 ILE A CA  1 
ATOM   2987 C C   . ILE A 1 405 ? 136.262 122.347 170.323 1.00 202.23 ? 406 ILE A C   1 
ATOM   2988 O O   . ILE A 1 405 ? 136.284 121.707 169.264 1.00 200.77 ? 406 ILE A O   1 
ATOM   2989 C CB  . ILE A 1 405 ? 138.000 121.769 172.091 1.00 204.22 ? 406 ILE A CB  1 
ATOM   2990 C CG1 . ILE A 1 405 ? 139.267 122.277 172.790 1.00 201.27 ? 406 ILE A CG1 1 
ATOM   2991 C CG2 . ILE A 1 405 ? 138.240 120.380 171.496 1.00 201.23 ? 406 ILE A CG2 1 
ATOM   2992 C CD1 . ILE A 1 405 ? 139.916 121.274 173.734 1.00 201.41 ? 406 ILE A CD1 1 
ATOM   2993 N N   . VAL A 1 406 ? 135.117 122.713 170.910 1.00 202.94 ? 407 VAL A N   1 
ATOM   2994 C CA  . VAL A 1 406 ? 133.816 122.349 170.348 1.00 202.69 ? 407 VAL A CA  1 
ATOM   2995 C C   . VAL A 1 406 ? 133.588 123.053 169.014 1.00 197.98 ? 407 VAL A C   1 
ATOM   2996 O O   . VAL A 1 406 ? 133.101 122.451 168.049 1.00 193.37 ? 407 VAL A O   1 
ATOM   2997 C CB  . VAL A 1 406 ? 132.694 122.667 171.355 1.00 202.05 ? 407 VAL A CB  1 
ATOM   2998 C CG1 . VAL A 1 406 ? 131.357 122.135 170.859 1.00 200.80 ? 407 VAL A CG1 1 
ATOM   2999 C CG2 . VAL A 1 406 ? 133.032 122.092 172.724 1.00 196.35 ? 407 VAL A CG2 1 
ATOM   3000 N N   . LEU A 1 407 ? 133.947 124.338 168.936 1.00 197.77 ? 408 LEU A N   1 
ATOM   3001 C CA  . LEU A 1 407 ? 133.835 125.059 167.672 1.00 192.06 ? 408 LEU A CA  1 
ATOM   3002 C C   . LEU A 1 407 ? 134.885 124.601 166.669 1.00 192.38 ? 408 LEU A C   1 
ATOM   3003 O O   . LEU A 1 407 ? 134.697 124.763 165.459 1.00 191.16 ? 408 LEU A O   1 
ATOM   3004 C CB  . LEU A 1 407 ? 133.916 126.574 167.918 1.00 196.66 ? 408 LEU A CB  1 
ATOM   3005 C CG  . LEU A 1 407 ? 135.157 127.342 168.412 1.00 195.88 ? 408 LEU A CG  1 
ATOM   3006 C CD1 . LEU A 1 407 ? 136.172 127.722 167.325 1.00 190.74 ? 408 LEU A CD1 1 
ATOM   3007 C CD2 . LEU A 1 407 ? 134.712 128.592 169.163 1.00 194.81 ? 408 LEU A CD2 1 
ATOM   3008 N N   . GLY A 1 408 ? 135.994 124.033 167.148 1.00 197.46 ? 409 GLY A N   1 
ATOM   3009 C CA  . GLY A 1 408 ? 137.043 123.576 166.255 1.00 201.62 ? 409 GLY A CA  1 
ATOM   3010 C C   . GLY A 1 408 ? 136.704 122.309 165.497 1.00 202.47 ? 409 GLY A C   1 
ATOM   3011 O O   . GLY A 1 408 ? 137.379 121.991 164.511 1.00 195.89 ? 409 GLY A O   1 
ATOM   3012 N N   . CYS A 1 409 ? 135.682 121.572 165.941 1.00 206.93 ? 410 CYS A N   1 
ATOM   3013 C CA  . CYS A 1 409 ? 135.280 120.349 165.252 1.00 205.98 ? 410 CYS A CA  1 
ATOM   3014 C C   . CYS A 1 409 ? 134.680 120.656 163.885 1.00 205.30 ? 410 CYS A C   1 
ATOM   3015 O O   . CYS A 1 409 ? 135.062 120.051 162.878 1.00 202.39 ? 410 CYS A O   1 
ATOM   3016 C CB  . CYS A 1 409 ? 134.286 119.561 166.109 1.00 206.01 ? 410 CYS A CB  1 
ATOM   3017 S SG  . CYS A 1 409 ? 134.844 119.192 167.786 1.00 214.00 ? 410 CYS A SG  1 
ATOM   3018 N N   . VAL A 1 410 ? 133.744 121.611 163.831 1.00 207.68 ? 411 VAL A N   1 
ATOM   3019 C CA  . VAL A 1 410 ? 133.073 121.942 162.574 1.00 204.26 ? 411 VAL A CA  1 
ATOM   3020 C C   . VAL A 1 410 ? 134.034 122.644 161.617 1.00 202.09 ? 411 VAL A C   1 
ATOM   3021 O O   . VAL A 1 410 ? 133.870 122.571 160.391 1.00 195.56 ? 411 VAL A O   1 
ATOM   3022 C CB  . VAL A 1 410 ? 131.795 122.770 162.862 1.00 202.92 ? 411 VAL A CB  1 
ATOM   3023 C CG1 . VAL A 1 410 ? 132.119 124.146 163.443 1.00 201.53 ? 411 VAL A CG1 1 
ATOM   3024 C CG2 . VAL A 1 410 ? 130.892 122.875 161.630 1.00 198.23 ? 411 VAL A CG2 1 
ATOM   3025 N N   . VAL A 1 411 ? 135.066 123.306 162.152 1.00 202.78 ? 412 VAL A N   1 
ATOM   3026 C CA  . VAL A 1 411 ? 136.169 123.778 161.319 1.00 200.58 ? 412 VAL A CA  1 
ATOM   3027 C C   . VAL A 1 411 ? 136.930 122.593 160.736 1.00 201.20 ? 412 VAL A C   1 
ATOM   3028 O O   . VAL A 1 411 ? 137.264 122.572 159.544 1.00 199.32 ? 412 VAL A O   1 
ATOM   3029 C CB  . VAL A 1 411 ? 137.093 124.703 162.133 1.00 192.16 ? 412 VAL A CB  1 
ATOM   3030 C CG1 . VAL A 1 411 ? 138.212 125.249 161.260 1.00 192.77 ? 412 VAL A CG1 1 
ATOM   3031 C CG2 . VAL A 1 411 ? 136.294 125.838 162.743 1.00 189.28 ? 412 VAL A CG2 1 
ATOM   3032 N N   . LEU A 1 412 ? 137.193 121.579 161.560 1.00 200.54 ? 413 LEU A N   1 
ATOM   3033 C CA  . LEU A 1 412 ? 137.880 120.379 161.103 1.00 198.40 ? 413 LEU A CA  1 
ATOM   3034 C C   . LEU A 1 412 ? 136.962 119.404 160.378 1.00 196.91 ? 413 LEU A C   1 
ATOM   3035 O O   . LEU A 1 412 ? 137.464 118.496 159.707 1.00 197.10 ? 413 LEU A O   1 
ATOM   3036 C CB  . LEU A 1 412 ? 138.547 119.677 162.289 1.00 200.93 ? 413 LEU A CB  1 
ATOM   3037 C CG  . LEU A 1 412 ? 139.972 120.128 162.617 1.00 200.42 ? 413 LEU A CG  1 
ATOM   3038 C CD1 . LEU A 1 412 ? 140.530 119.338 163.790 1.00 200.15 ? 413 LEU A CD1 1 
ATOM   3039 C CD2 . LEU A 1 412 ? 140.874 119.992 161.399 1.00 193.64 ? 413 LEU A CD2 1 
ATOM   3040 N N   . LEU A 1 413 ? 135.642 119.563 160.488 1.00 196.79 ? 414 LEU A N   1 
ATOM   3041 C CA  . LEU A 1 413 ? 134.706 118.753 159.716 1.00 198.35 ? 414 LEU A CA  1 
ATOM   3042 C C   . LEU A 1 413 ? 134.526 119.261 158.293 1.00 194.07 ? 414 LEU A C   1 
ATOM   3043 O O   . LEU A 1 413 ? 133.823 118.621 157.504 1.00 187.78 ? 414 LEU A O   1 
ATOM   3044 C CB  . LEU A 1 413 ? 133.341 118.685 160.412 1.00 198.98 ? 414 LEU A CB  1 
ATOM   3045 C CG  . LEU A 1 413 ? 133.204 117.676 161.555 1.00 200.68 ? 414 LEU A CG  1 
ATOM   3046 C CD1 . LEU A 1 413 ? 131.965 117.968 162.389 1.00 204.46 ? 414 LEU A CD1 1 
ATOM   3047 C CD2 . LEU A 1 413 ? 133.172 116.254 161.018 1.00 200.92 ? 414 LEU A CD2 1 
ATOM   3048 N N   . MET A 1 414 ? 135.140 120.395 157.949 1.00 192.37 ? 415 MET A N   1 
ATOM   3049 C CA  . MET A 1 414 ? 135.195 120.846 156.566 1.00 186.89 ? 415 MET A CA  1 
ATOM   3050 C C   . MET A 1 414 ? 136.237 120.091 155.752 1.00 179.66 ? 415 MET A C   1 
ATOM   3051 O O   . MET A 1 414 ? 136.292 120.276 154.533 1.00 172.87 ? 415 MET A O   1 
ATOM   3052 C CB  . MET A 1 414 ? 135.493 122.347 156.521 1.00 187.93 ? 415 MET A CB  1 
ATOM   3053 C CG  . MET A 1 414 ? 134.412 123.223 157.136 1.00 188.48 ? 415 MET A CG  1 
ATOM   3054 S SD  . MET A 1 414 ? 132.843 123.128 156.254 1.00 202.58 ? 415 MET A SD  1 
ATOM   3055 C CE  . MET A 1 414 ? 131.781 124.063 157.352 1.00 192.34 ? 415 MET A CE  1 
ATOM   3056 N N   . VAL A 1 415 ? 137.070 119.271 156.407 1.00 186.07 ? 416 VAL A N   1 
ATOM   3057 C CA  . VAL A 1 415 ? 138.093 118.500 155.689 1.00 186.70 ? 416 VAL A CA  1 
ATOM   3058 C C   . VAL A 1 415 ? 137.512 117.488 154.695 1.00 182.05 ? 416 VAL A C   1 
ATOM   3059 O O   . VAL A 1 415 ? 137.964 117.478 153.538 1.00 177.24 ? 416 VAL A O   1 
ATOM   3060 C CB  . VAL A 1 415 ? 139.079 117.873 156.691 1.00 188.35 ? 416 VAL A CB  1 
ATOM   3061 C CG1 . VAL A 1 415 ? 139.965 116.822 156.026 1.00 183.32 ? 416 VAL A CG1 1 
ATOM   3062 C CG2 . VAL A 1 415 ? 139.926 118.945 157.356 1.00 188.16 ? 416 VAL A CG2 1 
ATOM   3063 N N   . PRO A 1 416 ? 136.525 116.625 155.050 1.00 182.72 ? 417 PRO A N   1 
ATOM   3064 C CA  . PRO A 1 416 ? 136.008 115.723 153.998 1.00 179.72 ? 417 PRO A CA  1 
ATOM   3065 C C   . PRO A 1 416 ? 135.186 116.437 152.940 1.00 173.31 ? 417 PRO A C   1 
ATOM   3066 O O   . PRO A 1 416 ? 135.095 115.955 151.803 1.00 166.32 ? 417 PRO A O   1 
ATOM   3067 C CB  . PRO A 1 416 ? 135.158 114.698 154.765 1.00 180.71 ? 417 PRO A CB  1 
ATOM   3068 C CG  . PRO A 1 416 ? 135.391 114.920 156.177 1.00 179.56 ? 417 PRO A CG  1 
ATOM   3069 C CD  . PRO A 1 416 ? 135.898 116.296 156.352 1.00 179.63 ? 417 PRO A CD  1 
ATOM   3070 N N   . LEU A 1 417 ? 134.571 117.569 153.286 1.00 177.89 ? 418 LEU A N   1 
ATOM   3071 C CA  . LEU A 1 417 ? 133.842 118.345 152.291 1.00 171.63 ? 418 LEU A CA  1 
ATOM   3072 C C   . LEU A 1 417 ? 134.793 118.998 151.296 1.00 164.24 ? 418 LEU A C   1 
ATOM   3073 O O   . LEU A 1 417 ? 134.631 118.845 150.082 1.00 163.78 ? 418 LEU A O   1 
ATOM   3074 C CB  . LEU A 1 417 ? 132.975 119.399 152.979 1.00 175.68 ? 418 LEU A CB  1 
ATOM   3075 C CG  . LEU A 1 417 ? 132.131 120.276 152.051 1.00 173.71 ? 418 LEU A CG  1 
ATOM   3076 C CD1 . LEU A 1 417 ? 131.081 119.444 151.331 1.00 172.32 ? 418 LEU A CD1 1 
ATOM   3077 C CD2 . LEU A 1 417 ? 131.483 121.412 152.827 1.00 173.96 ? 418 LEU A CD2 1 
ATOM   3078 N N   . ASN A 1 418 ? 135.815 119.700 151.794 1.00 163.87 ? 419 ASN A N   1 
ATOM   3079 C CA  . ASN A 1 418 ? 136.674 120.490 150.916 1.00 159.48 ? 419 ASN A CA  1 
ATOM   3080 C C   . ASN A 1 418 ? 137.624 119.617 150.108 1.00 161.11 ? 419 ASN A C   1 
ATOM   3081 O O   . ASN A 1 418 ? 138.084 120.031 149.038 1.00 158.23 ? 419 ASN A O   1 
ATOM   3082 C CB  . ASN A 1 418 ? 137.465 121.510 151.734 1.00 162.77 ? 419 ASN A CB  1 
ATOM   3083 C CG  . ASN A 1 418 ? 136.728 122.823 151.895 1.00 161.61 ? 419 ASN A CG  1 
ATOM   3084 O OD1 . ASN A 1 418 ? 135.737 123.077 151.213 1.00 160.66 ? 419 ASN A OD1 1 
ATOM   3085 N ND2 . ASN A 1 418 ? 137.200 123.660 152.813 1.00 156.70 ? 419 ASN A ND2 1 
ATOM   3086 N N   . MET A 1 419 ? 137.942 118.419 150.602 1.00 166.03 ? 420 MET A N   1 
ATOM   3087 C CA  . MET A 1 419 ? 138.768 117.503 149.822 1.00 159.34 ? 420 MET A CA  1 
ATOM   3088 C C   . MET A 1 419 ? 137.995 116.961 148.627 1.00 159.25 ? 420 MET A C   1 
ATOM   3089 O O   . MET A 1 419 ? 138.565 116.739 147.552 1.00 150.89 ? 420 MET A O   1 
ATOM   3090 C CB  . MET A 1 419 ? 139.269 116.363 150.709 1.00 158.69 ? 420 MET A CB  1 
ATOM   3091 C CG  . MET A 1 419 ? 140.249 115.423 150.029 1.00 159.36 ? 420 MET A CG  1 
ATOM   3092 S SD  . MET A 1 419 ? 141.774 116.256 149.552 1.00 162.93 ? 420 MET A SD  1 
ATOM   3093 C CE  . MET A 1 419 ? 142.547 116.490 151.150 1.00 163.08 ? 420 MET A CE  1 
ATOM   3094 N N   . TYR A 1 420 ? 136.687 116.770 148.791 1.00 163.76 ? 421 TYR A N   1 
ATOM   3095 C CA  . TYR A 1 420 ? 135.823 116.250 147.743 1.00 154.07 ? 421 TYR A CA  1 
ATOM   3096 C C   . TYR A 1 420 ? 135.281 117.330 146.816 1.00 148.09 ? 421 TYR A C   1 
ATOM   3097 O O   . TYR A 1 420 ? 135.095 117.062 145.624 1.00 149.31 ? 421 TYR A O   1 
ATOM   3098 C CB  . TYR A 1 420 ? 134.654 115.478 148.376 1.00 152.84 ? 421 TYR A CB  1 
ATOM   3099 C CG  . TYR A 1 420 ? 133.570 115.054 147.411 1.00 152.25 ? 421 TYR A CG  1 
ATOM   3100 C CD1 . TYR A 1 420 ? 133.778 114.009 146.520 1.00 155.31 ? 421 TYR A CD1 1 
ATOM   3101 C CD2 . TYR A 1 420 ? 132.333 115.689 147.404 1.00 155.55 ? 421 TYR A CD2 1 
ATOM   3102 C CE1 . TYR A 1 420 ? 132.787 113.615 145.636 1.00 161.52 ? 421 TYR A CE1 1 
ATOM   3103 C CE2 . TYR A 1 420 ? 131.336 115.303 146.525 1.00 162.13 ? 421 TYR A CE2 1 
ATOM   3104 C CZ  . TYR A 1 420 ? 131.569 114.265 145.645 1.00 164.60 ? 421 TYR A CZ  1 
ATOM   3105 O OH  . TYR A 1 420 ? 130.580 113.877 144.770 1.00 163.92 ? 421 TYR A OH  1 
ATOM   3106 N N   . ILE A 1 421 ? 135.049 118.545 147.314 1.00 146.76 ? 422 ILE A N   1 
ATOM   3107 C CA  . ILE A 1 421 ? 134.298 119.523 146.535 1.00 147.01 ? 422 ILE A CA  1 
ATOM   3108 C C   . ILE A 1 421 ? 135.200 120.460 145.731 1.00 143.11 ? 422 ILE A C   1 
ATOM   3109 O O   . ILE A 1 421 ? 134.723 121.094 144.779 1.00 142.49 ? 422 ILE A O   1 
ATOM   3110 C CB  . ILE A 1 421 ? 133.349 120.308 147.466 1.00 152.95 ? 422 ILE A CB  1 
ATOM   3111 C CG1 . ILE A 1 421 ? 132.104 120.780 146.722 1.00 146.93 ? 422 ILE A CG1 1 
ATOM   3112 C CG2 . ILE A 1 421 ? 134.047 121.492 148.119 1.00 153.56 ? 422 ILE A CG2 1 
ATOM   3113 C CD1 . ILE A 1 421 ? 131.223 119.642 146.273 1.00 145.68 ? 422 ILE A CD1 1 
ATOM   3114 N N   . LEU A 1 422 ? 136.509 120.552 146.067 1.00 142.98 ? 423 LEU A N   1 
ATOM   3115 C CA  . LEU A 1 422 ? 137.400 121.397 145.272 1.00 135.91 ? 423 LEU A CA  1 
ATOM   3116 C C   . LEU A 1 422 ? 137.937 120.626 144.078 1.00 135.55 ? 423 LEU A C   1 
ATOM   3117 O O   . LEU A 1 422 ? 138.273 119.441 144.215 1.00 138.32 ? 423 LEU A O   1 
ATOM   3118 C CB  . LEU A 1 422 ? 138.567 121.922 146.107 1.00 134.92 ? 423 LEU A CB  1 
ATOM   3119 C CG  . LEU A 1 422 ? 138.450 123.195 146.961 1.00 133.38 ? 423 LEU A CG  1 
ATOM   3120 C CD1 . LEU A 1 422 ? 138.197 124.405 146.072 1.00 125.18 ? 423 LEU A CD1 1 
ATOM   3121 C CD2 . LEU A 1 422 ? 137.409 123.113 148.062 1.00 143.11 ? 423 LEU A CD2 1 
ATOM   3122 N N   . PRO A 1 423 ? 138.031 121.248 142.905 1.00 135.52 ? 424 PRO A N   1 
ATOM   3123 C CA  . PRO A 1 423 ? 138.601 120.558 141.745 1.00 131.03 ? 424 PRO A CA  1 
ATOM   3124 C C   . PRO A 1 423 ? 140.115 120.447 141.846 1.00 131.37 ? 424 PRO A C   1 
ATOM   3125 O O   . PRO A 1 423 ? 140.771 121.133 142.632 1.00 131.83 ? 424 PRO A O   1 
ATOM   3126 C CB  . PRO A 1 423 ? 138.191 121.446 140.568 1.00 134.35 ? 424 PRO A CB  1 
ATOM   3127 C CG  . PRO A 1 423 ? 138.053 122.802 141.164 1.00 136.79 ? 424 PRO A CG  1 
ATOM   3128 C CD  . PRO A 1 423 ? 137.528 122.589 142.556 1.00 142.24 ? 424 PRO A CD  1 
ATOM   3129 N N   . ASN A 1 424 ? 140.666 119.561 141.023 1.00 132.62 ? 425 ASN A N   1 
ATOM   3130 C CA  . ASN A 1 424 ? 142.102 119.329 140.960 1.00 131.46 ? 425 ASN A CA  1 
ATOM   3131 C C   . ASN A 1 424 ? 142.678 120.035 139.739 1.00 130.33 ? 425 ASN A C   1 
ATOM   3132 O O   . ASN A 1 424 ? 142.185 119.850 138.621 1.00 135.08 ? 425 ASN A O   1 
ATOM   3133 C CB  . ASN A 1 424 ? 142.408 117.832 140.887 1.00 139.30 ? 425 ASN A CB  1 
ATOM   3134 C CG  . ASN A 1 424 ? 141.963 117.083 142.125 1.00 137.37 ? 425 ASN A CG  1 
ATOM   3135 O OD1 . ASN A 1 424 ? 142.489 117.295 143.214 1.00 135.63 ? 425 ASN A OD1 1 
ATOM   3136 N ND2 . ASN A 1 424 ? 140.988 116.198 141.962 1.00 138.23 ? 425 ASN A ND2 1 
ATOM   3137 N N   . TYR A 1 425 ? 143.718 120.834 139.954 1.00 127.62 ? 426 TYR A N   1 
ATOM   3138 C CA  . TYR A 1 425 ? 144.420 121.515 138.877 1.00 131.10 ? 426 TYR A CA  1 
ATOM   3139 C C   . TYR A 1 425 ? 145.889 121.117 138.882 1.00 133.44 ? 426 TYR A C   1 
ATOM   3140 O O   . TYR A 1 425 ? 146.439 120.714 139.911 1.00 134.92 ? 426 TYR A O   1 
ATOM   3141 C CB  . TYR A 1 425 ? 144.309 123.040 138.998 1.00 131.34 ? 426 TYR A CB  1 
ATOM   3142 C CG  . TYR A 1 425 ? 142.906 123.589 138.881 1.00 128.28 ? 426 TYR A CG  1 
ATOM   3143 C CD1 . TYR A 1 425 ? 141.983 123.014 138.017 1.00 130.98 ? 426 TYR A CD1 1 
ATOM   3144 C CD2 . TYR A 1 425 ? 142.513 124.697 139.620 1.00 127.56 ? 426 TYR A CD2 1 
ATOM   3145 C CE1 . TYR A 1 425 ? 140.700 123.519 137.904 1.00 135.45 ? 426 TYR A CE1 1 
ATOM   3146 C CE2 . TYR A 1 425 ? 141.234 125.210 139.513 1.00 129.72 ? 426 TYR A CE2 1 
ATOM   3147 C CZ  . TYR A 1 425 ? 140.333 124.618 138.655 1.00 132.90 ? 426 TYR A CZ  1 
ATOM   3148 O OH  . TYR A 1 425 ? 139.059 125.127 138.546 1.00 132.94 ? 426 TYR A OH  1 
ATOM   3149 N N   . GLU A 1 426 ? 146.518 121.229 137.715 1.00 133.60 ? 427 GLU A N   1 
ATOM   3150 C CA  . GLU A 1 426 ? 147.946 120.997 137.564 1.00 133.44 ? 427 GLU A CA  1 
ATOM   3151 C C   . GLU A 1 426 ? 148.505 121.963 136.531 1.00 133.33 ? 427 GLU A C   1 
ATOM   3152 O O   . GLU A 1 426 ? 147.812 122.353 135.587 1.00 135.11 ? 427 GLU A O   1 
ATOM   3153 C CB  . GLU A 1 426 ? 148.232 119.526 137.179 1.00 138.38 ? 427 GLU A CB  1 
ATOM   3154 C CG  . GLU A 1 426 ? 147.603 119.029 135.870 1.00 144.08 ? 427 GLU A CG  1 
ATOM   3155 C CD  . GLU A 1 426 ? 148.456 119.290 134.639 1.00 150.55 ? 427 GLU A CD  1 
ATOM   3156 O OE1 . GLU A 1 426 ? 149.676 119.508 134.794 1.00 148.73 ? 427 GLU A OE1 1 
ATOM   3157 O OE2 . GLU A 1 426 ? 147.904 119.277 133.519 1.00 149.49 ? 427 GLU A OE2 1 
ATOM   3158 N N   . SER A 1 427 ? 149.766 122.349 136.715 1.00 134.64 ? 428 SER A N   1 
ATOM   3159 C CA  . SER A 1 427 ? 150.413 123.266 135.789 1.00 142.64 ? 428 SER A CA  1 
ATOM   3160 C C   . SER A 1 427 ? 151.921 123.071 135.831 1.00 142.01 ? 428 SER A C   1 
ATOM   3161 O O   . SER A 1 427 ? 152.493 122.743 136.874 1.00 139.54 ? 428 SER A O   1 
ATOM   3162 C CB  . SER A 1 427 ? 150.073 124.726 136.105 1.00 143.95 ? 428 SER A CB  1 
ATOM   3163 O OG  . SER A 1 427 ? 150.741 125.603 135.215 1.00 138.84 ? 428 SER A OG  1 
ATOM   3164 N N   . ASP A 1 428 ? 152.550 123.270 134.678 1.00 142.14 ? 429 ASP A N   1 
ATOM   3165 C CA  . ASP A 1 428 ? 154.002 123.282 134.601 1.00 144.12 ? 429 ASP A CA  1 
ATOM   3166 C C   . ASP A 1 428 ? 154.530 124.529 135.308 1.00 147.69 ? 429 ASP A C   1 
ATOM   3167 O O   . ASP A 1 428 ? 153.930 125.603 135.187 1.00 151.15 ? 429 ASP A O   1 
ATOM   3168 C CB  . ASP A 1 428 ? 154.443 123.280 133.134 1.00 145.81 ? 429 ASP A CB  1 
ATOM   3169 C CG  . ASP A 1 428 ? 155.733 122.511 132.893 1.00 142.15 ? 429 ASP A CG  1 
ATOM   3170 O OD1 . ASP A 1 428 ? 156.328 121.986 133.854 1.00 136.52 ? 429 ASP A OD1 1 
ATOM   3171 O OD2 . ASP A 1 428 ? 156.156 122.432 131.721 1.00 140.12 ? 429 ASP A OD2 1 
ATOM   3172 N N   . PRO A 1 429 ? 155.600 124.411 136.099 1.00 146.16 ? 430 PRO A N   1 
ATOM   3173 C CA  . PRO A 1 429 ? 156.230 125.609 136.672 1.00 150.78 ? 430 PRO A CA  1 
ATOM   3174 C C   . PRO A 1 429 ? 156.765 126.561 135.609 1.00 149.40 ? 430 PRO A C   1 
ATOM   3175 O O   . PRO A 1 429 ? 157.280 126.144 134.571 1.00 143.39 ? 430 PRO A O   1 
ATOM   3176 C CB  . PRO A 1 429 ? 157.359 125.031 137.529 1.00 146.78 ? 430 PRO A CB  1 
ATOM   3177 C CG  . PRO A 1 429 ? 156.833 123.717 137.965 1.00 140.93 ? 430 PRO A CG  1 
ATOM   3178 C CD  . PRO A 1 429 ? 156.008 123.191 136.819 1.00 138.26 ? 430 PRO A CD  1 
ATOM   3179 N N   . GLY A 1 430 ? 156.632 127.857 135.887 1.00 145.20 ? 431 GLY A N   1 
ATOM   3180 C CA  . GLY A 1 430 ? 157.049 128.886 134.953 1.00 147.32 ? 431 GLY A CA  1 
ATOM   3181 C C   . GLY A 1 430 ? 158.509 129.242 135.140 1.00 152.99 ? 431 GLY A C   1 
ATOM   3182 O O   . GLY A 1 430 ? 159.003 129.312 136.268 1.00 154.28 ? 431 GLY A O   1 
ATOM   3183 N N   . GLU A 1 431 ? 159.198 129.474 134.022 1.00 156.29 ? 432 GLU A N   1 
ATOM   3184 C CA  . GLU A 1 431 ? 160.633 129.729 134.051 1.00 157.63 ? 432 GLU A CA  1 
ATOM   3185 C C   . GLU A 1 431 ? 160.976 131.186 134.330 1.00 156.32 ? 432 GLU A C   1 
ATOM   3186 O O   . GLU A 1 431 ? 162.164 131.512 134.421 1.00 156.40 ? 432 GLU A O   1 
ATOM   3187 C CB  . GLU A 1 431 ? 161.265 129.291 132.729 1.00 161.08 ? 432 GLU A CB  1 
ATOM   3188 C CG  . GLU A 1 431 ? 160.878 127.885 132.299 1.00 158.79 ? 432 GLU A CG  1 
ATOM   3189 C CD  . GLU A 1 431 ? 161.274 127.582 130.867 1.00 159.95 ? 432 GLU A CD  1 
ATOM   3190 O OE1 . GLU A 1 431 ? 161.873 128.464 130.216 1.00 159.70 ? 432 GLU A OE1 1 
ATOM   3191 O OE2 . GLU A 1 431 ? 160.984 126.464 130.392 1.00 164.12 ? 432 GLU A OE2 1 
ATOM   3192 N N   . HIS A 1 432 ? 159.982 132.062 134.455 1.00 156.15 ? 433 HIS A N   1 
ATOM   3193 C CA  . HIS A 1 432 ? 160.253 133.454 134.791 1.00 160.56 ? 433 HIS A CA  1 
ATOM   3194 C C   . HIS A 1 432 ? 160.684 133.577 136.247 1.00 161.16 ? 433 HIS A C   1 
ATOM   3195 O O   . HIS A 1 432 ? 160.060 133.001 137.143 1.00 164.82 ? 433 HIS A O   1 
ATOM   3196 C CB  . HIS A 1 432 ? 159.014 134.314 134.534 1.00 158.48 ? 433 HIS A CB  1 
ATOM   3197 C CG  . HIS A 1 432 ? 158.613 134.381 133.094 1.00 160.72 ? 433 HIS A CG  1 
ATOM   3198 N ND1 . HIS A 1 432 ? 159.291 135.143 132.167 1.00 165.55 ? 433 HIS A ND1 1 
ATOM   3199 C CD2 . HIS A 1 432 ? 157.607 133.776 132.420 1.00 156.18 ? 433 HIS A CD2 1 
ATOM   3200 C CE1 . HIS A 1 432 ? 158.717 135.008 130.985 1.00 165.04 ? 433 HIS A CE1 1 
ATOM   3201 N NE2 . HIS A 1 432 ? 157.693 134.184 131.111 1.00 158.93 ? 433 HIS A NE2 1 
ATOM   3202 N N   . SER A 1 433 ? 161.758 134.324 136.479 1.00 154.67 ? 434 SER A N   1 
ATOM   3203 C CA  . SER A 1 433 ? 162.220 134.577 137.833 1.00 159.56 ? 434 SER A CA  1 
ATOM   3204 C C   . SER A 1 433 ? 161.292 135.560 138.539 1.00 159.56 ? 434 SER A C   1 
ATOM   3205 O O   . SER A 1 433 ? 160.690 136.439 137.916 1.00 159.45 ? 434 SER A O   1 
ATOM   3206 C CB  . SER A 1 433 ? 163.649 135.120 137.822 1.00 160.52 ? 434 SER A CB  1 
ATOM   3207 O OG  . SER A 1 433 ? 163.699 136.416 137.252 1.00 163.98 ? 434 SER A OG  1 
ATOM   3208 N N   . PHE A 1 434 ? 161.176 135.393 139.859 1.00 152.54 ? 435 PHE A N   1 
ATOM   3209 C CA  . PHE A 1 434 ? 160.314 136.263 140.652 1.00 146.20 ? 435 PHE A CA  1 
ATOM   3210 C C   . PHE A 1 434 ? 160.911 137.660 140.792 1.00 146.38 ? 435 PHE A C   1 
ATOM   3211 O O   . PHE A 1 434 ? 160.166 138.642 140.880 1.00 141.58 ? 435 PHE A O   1 
ATOM   3212 C CB  . PHE A 1 434 ? 160.058 135.602 142.015 1.00 144.42 ? 435 PHE A CB  1 
ATOM   3213 C CG  . PHE A 1 434 ? 158.917 136.204 142.811 1.00 137.80 ? 435 PHE A CG  1 
ATOM   3214 C CD1 . PHE A 1 434 ? 159.070 137.379 143.539 1.00 132.44 ? 435 PHE A CD1 1 
ATOM   3215 C CD2 . PHE A 1 434 ? 157.676 135.590 142.806 1.00 136.28 ? 435 PHE A CD2 1 
ATOM   3216 C CE1 . PHE A 1 434 ? 158.016 137.912 144.252 1.00 128.78 ? 435 PHE A CE1 1 
ATOM   3217 C CE2 . PHE A 1 434 ? 156.619 136.122 143.515 1.00 137.16 ? 435 PHE A CE2 1 
ATOM   3218 C CZ  . PHE A 1 434 ? 156.790 137.280 144.239 1.00 132.02 ? 435 PHE A CZ  1 
ATOM   3219 C CA  . TRP A 1 435 ? 162.934 138.912 140.869 1.00 148.57 ? 436 TRP A CA  1 
ATOM   3220 C C   . TRP A 1 435 ? 162.765 139.874 139.698 1.00 153.61 ? 436 TRP A C   1 
ATOM   3221 O O   . TRP A 1 435 ? 163.131 141.047 139.818 1.00 151.16 ? 436 TRP A O   1 
ATOM   3222 C CB  . TRP A 1 435 ? 164.420 138.664 141.130 1.00 147.50 ? 436 TRP A CB  1 
ATOM   3223 C CG  . TRP A 1 435 ? 164.971 139.486 142.260 1.00 144.49 ? 436 TRP A CG  1 
ATOM   3224 C CD1 . TRP A 1 435 ? 164.256 140.178 143.192 1.00 137.60 ? 436 TRP A CD1 1 
ATOM   3225 C CD2 . TRP A 1 435 ? 166.353 139.703 142.573 1.00 139.33 ? 436 TRP A CD2 1 
ATOM   3226 N NE1 . TRP A 1 435 ? 165.105 140.811 144.066 1.00 135.65 ? 436 TRP A NE1 1 
ATOM   3227 C CE2 . TRP A 1 435 ? 166.398 140.535 143.707 1.00 136.30 ? 436 TRP A CE2 1 
ATOM   3228 C CE3 . TRP A 1 435 ? 167.556 139.274 142.004 1.00 132.91 ? 436 TRP A CE3 1 
ATOM   3229 C CZ2 . TRP A 1 435 ? 167.596 140.947 144.283 1.00 134.23 ? 436 TRP A CZ2 1 
ATOM   3230 C CZ3 . TRP A 1 435 ? 168.744 139.684 142.577 1.00 128.53 ? 436 TRP A CZ3 1 
ATOM   3231 C CH2 . TRP A 1 435 ? 168.756 140.511 143.704 1.00 129.58 ? 436 TRP A CH2 1 
ATOM   3232 N N   . LYS A 1 436 ? 162.367 139.547 138.657 1.00 153.81 ? 437 LYS A N   1 
ATOM   3233 C CA  . LYS A 1 436 ? 162.016 140.434 137.555 1.00 151.98 ? 437 LYS A CA  1 
ATOM   3234 C C   . LYS A 1 436 ? 160.687 141.141 137.803 1.00 147.77 ? 437 LYS A C   1 
ATOM   3235 O O   . LYS A 1 436 ? 160.538 142.314 137.438 1.00 145.65 ? 437 LYS A O   1 
ATOM   3236 C CB  . LYS A 1 436 ? 161.985 139.631 136.247 1.00 157.40 ? 437 LYS A CB  1 
ATOM   3237 C CG  . LYS A 1 436 ? 161.341 140.321 135.049 1.00 158.04 ? 437 LYS A CG  1 
ATOM   3238 C CD  . LYS A 1 436 ? 161.128 139.354 133.897 1.00 159.15 ? 437 LYS A CD  1 
ATOM   3239 C CE  . LYS A 1 436 ? 160.346 140.008 132.770 1.00 157.28 ? 437 LYS A CE  1 
ATOM   3240 N NZ  . LYS A 1 436 ? 159.961 139.029 131.718 1.00 158.70 ? 437 LYS A NZ  1 
ATOM   3241 N N   . LEU A 1 437 ? 159.739 140.458 138.459 1.00 142.99 ? 438 LEU A N   1 
ATOM   3242 C CA  . LEU A 1 437 ? 158.400 141.004 138.678 1.00 139.91 ? 438 LEU A CA  1 
ATOM   3243 C C   . LEU A 1 437 ? 158.421 142.215 139.607 1.00 139.29 ? 438 LEU A C   1 
ATOM   3244 O O   . LEU A 1 437 ? 157.680 143.181 139.389 1.00 138.70 ? 438 LEU A O   1 
ATOM   3245 C CB  . LEU A 1 437 ? 157.482 139.915 139.237 1.00 142.24 ? 438 LEU A CB  1 
ATOM   3246 C CG  . LEU A 1 437 ? 156.042 140.300 139.591 1.00 141.48 ? 438 LEU A CG  1 
ATOM   3247 C CD1 . LEU A 1 437 ? 155.285 140.767 138.359 1.00 140.01 ? 438 LEU A CD1 1 
ATOM   3248 C CD2 . LEU A 1 437 ? 155.317 139.140 140.257 1.00 128.86 ? 438 LEU A CD2 1 
ATOM   3249 N N   . ILE A 1 438 ? 159.272 142.195 140.636 1.00 142.04 ? 439 ILE A N   1 
ATOM   3250 C CA  . ILE A 1 438 ? 159.342 143.325 141.561 1.00 143.84 ? 439 ILE A CA  1 
ATOM   3251 C C   . ILE A 1 438 ? 160.179 144.476 141.032 1.00 140.29 ? 439 ILE A C   1 
ATOM   3252 O O   . ILE A 1 438 ? 160.256 145.522 141.688 1.00 140.43 ? 439 ILE A O   1 
ATOM   3253 C CB  . ILE A 1 438 ? 159.896 142.892 142.931 1.00 146.55 ? 439 ILE A CB  1 
ATOM   3254 C CG1 . ILE A 1 438 ? 161.325 142.368 142.791 1.00 140.16 ? 439 ILE A CG1 1 
ATOM   3255 C CG2 . ILE A 1 438 ? 158.997 141.839 143.561 1.00 147.04 ? 439 ILE A CG2 1 
ATOM   3256 C CD1 . ILE A 1 438 ? 162.023 142.138 144.114 1.00 142.31 ? 439 ILE A CD1 1 
ATOM   3257 N N   . ALA A 1 439 ? 160.808 144.321 139.868 1.00 140.77 ? 440 ALA A N   1 
ATOM   3258 C CA  . ALA A 1 439 ? 161.602 145.385 139.268 1.00 145.54 ? 440 ALA A CA  1 
ATOM   3259 C C   . ALA A 1 439 ? 160.803 146.268 138.316 1.00 135.67 ? 440 ALA A C   1 
ATOM   3260 O O   . ALA A 1 439 ? 161.384 147.169 137.703 1.00 130.70 ? 440 ALA A O   1 
ATOM   3261 C CB  . ALA A 1 439 ? 162.804 144.792 138.529 1.00 148.49 ? 440 ALA A CB  1 
ATOM   3262 N N   . LEU A 1 440 ? 159.503 146.029 138.167 1.00 132.94 ? 441 LEU A N   1 
ATOM   3263 C CA  . LEU A 1 440 ? 158.687 146.876 137.309 1.00 135.26 ? 441 LEU A CA  1 
ATOM   3264 C C   . LEU A 1 440 ? 158.448 148.228 137.979 1.00 139.44 ? 441 LEU A C   1 
ATOM   3265 O O   . LEU A 1 440 ? 158.445 148.318 139.211 1.00 138.14 ? 441 LEU A O   1 
ATOM   3266 C CB  . LEU A 1 440 ? 157.343 146.213 136.997 1.00 128.51 ? 441 LEU A CB  1 
ATOM   3267 C CG  . LEU A 1 440 ? 157.172 145.202 135.855 1.00 133.79 ? 441 LEU A CG  1 
ATOM   3268 C CD1 . LEU A 1 440 ? 157.448 145.863 134.509 1.00 131.06 ? 441 LEU A CD1 1 
ATOM   3269 C CD2 . LEU A 1 440 ? 158.003 143.936 136.023 1.00 140.47 ? 441 LEU A CD2 1 
ATOM   3270 N N   . PRO A 1 441 ? 158.274 149.300 137.199 1.00 137.73 ? 442 PRO A N   1 
ATOM   3271 C CA  . PRO A 1 441 ? 157.899 150.586 137.807 1.00 126.89 ? 442 PRO A CA  1 
ATOM   3272 C C   . PRO A 1 441 ? 156.496 150.597 138.386 1.00 122.07 ? 442 PRO A C   1 
ATOM   3273 O O   . PRO A 1 441 ? 156.255 151.289 139.382 1.00 122.04 ? 442 PRO A O   1 
ATOM   3274 C CB  . PRO A 1 441 ? 158.031 151.575 136.640 1.00 126.72 ? 442 PRO A CB  1 
ATOM   3275 C CG  . PRO A 1 441 ? 158.947 150.909 135.673 1.00 124.92 ? 442 PRO A CG  1 
ATOM   3276 C CD  . PRO A 1 441 ? 158.633 149.451 135.779 1.00 134.16 ? 442 PRO A CD  1 
ATOM   3277 N N   . LYS A 1 442 ? 155.564 149.845 137.803 1.00 120.97 ? 443 LYS A N   1 
ATOM   3278 C CA  . LYS A 1 442 ? 154.172 149.901 138.234 1.00 120.04 ? 443 LYS A CA  1 
ATOM   3279 C C   . LYS A 1 442 ? 153.906 148.997 139.434 1.00 118.95 ? 443 LYS A C   1 
ATOM   3280 O O   . LYS A 1 442 ? 153.139 149.370 140.330 1.00 118.21 ? 443 LYS A O   1 
ATOM   3281 C CB  . LYS A 1 442 ? 153.255 149.541 137.057 1.00 119.47 ? 443 LYS A CB  1 
ATOM   3282 C CG  . LYS A 1 442 ? 151.792 149.274 137.406 1.00 124.82 ? 443 LYS A CG  1 
ATOM   3283 C CD  . LYS A 1 442 ? 150.999 148.695 136.237 1.00 128.38 ? 443 LYS A CD  1 
ATOM   3284 C CE  . LYS A 1 442 ? 151.326 149.358 134.902 1.00 126.31 ? 443 LYS A CE  1 
ATOM   3285 N NZ  . LYS A 1 442 ? 151.006 150.814 134.890 1.00 126.54 ? 443 LYS A NZ  1 
ATOM   3286 N N   . VAL A 1 443 ? 154.550 147.826 139.480 1.00 122.46 ? 444 VAL A N   1 
ATOM   3287 C CA  . VAL A 1 443 ? 154.428 146.934 140.632 1.00 121.87 ? 444 VAL A CA  1 
ATOM   3288 C C   . VAL A 1 443 ? 155.063 147.558 141.869 1.00 116.27 ? 444 VAL A C   1 
ATOM   3289 O O   . VAL A 1 443 ? 154.581 147.361 142.992 1.00 116.90 ? 444 VAL A O   1 
ATOM   3290 C CB  . VAL A 1 443 ? 155.034 145.552 140.305 1.00 125.12 ? 444 VAL A CB  1 
ATOM   3291 C CG1 . VAL A 1 443 ? 154.729 144.539 141.401 1.00 129.42 ? 444 VAL A CG1 1 
ATOM   3292 C CG2 . VAL A 1 443 ? 154.483 145.043 138.992 1.00 123.27 ? 444 VAL A CG2 1 
ATOM   3293 N N   . GLY A 1 444 ? 156.139 148.326 141.687 1.00 114.79 ? 445 GLY A N   1 
ATOM   3294 C CA  . GLY A 1 444 ? 156.769 148.989 142.819 1.00 112.80 ? 445 GLY A CA  1 
ATOM   3295 C C   . GLY A 1 444 ? 155.906 150.076 143.433 1.00 115.07 ? 445 GLY A C   1 
ATOM   3296 O O   . GLY A 1 444 ? 155.876 150.240 144.655 1.00 120.07 ? 445 GLY A O   1 
ATOM   3297 N N   . LEU A 1 445 ? 155.196 150.837 142.598 1.00 114.97 ? 446 LEU A N   1 
ATOM   3298 C CA  . LEU A 1 445 ? 154.360 151.914 143.121 1.00 111.56 ? 446 LEU A CA  1 
ATOM   3299 C C   . LEU A 1 445 ? 153.063 151.383 143.718 1.00 114.29 ? 446 LEU A C   1 
ATOM   3300 O O   . LEU A 1 445 ? 152.548 151.948 144.689 1.00 116.34 ? 446 LEU A O   1 
ATOM   3301 C CB  . LEU A 1 445 ? 154.070 152.940 142.028 1.00 107.62 ? 446 LEU A CB  1 
ATOM   3302 C CG  . LEU A 1 445 ? 155.223 153.898 141.728 1.00 112.97 ? 446 LEU A CG  1 
ATOM   3303 C CD1 . LEU A 1 445 ? 155.222 154.311 140.272 1.00 119.17 ? 446 LEU A CD1 1 
ATOM   3304 C CD2 . LEU A 1 445 ? 155.148 155.114 142.632 1.00 115.41 ? 446 LEU A CD2 1 
ATOM   3305 N N   . ILE A 1 446 ? 152.513 150.302 143.155 1.00 114.11 ? 447 ILE A N   1 
ATOM   3306 C CA  . ILE A 1 446 ? 151.304 149.719 143.726 1.00 113.76 ? 447 ILE A CA  1 
ATOM   3307 C C   . ILE A 1 446 ? 151.631 148.946 145.002 1.00 115.42 ? 447 ILE A C   1 
ATOM   3308 O O   . ILE A 1 446 ? 150.748 148.726 145.840 1.00 120.37 ? 447 ILE A O   1 
ATOM   3309 C CB  . ILE A 1 446 ? 150.581 148.852 142.668 1.00 117.19 ? 447 ILE A CB  1 
ATOM   3310 C CG1 . ILE A 1 446 ? 149.128 148.576 143.060 1.00 117.71 ? 447 ILE A CG1 1 
ATOM   3311 C CG2 . ILE A 1 446 ? 151.271 147.524 142.470 1.00 117.35 ? 447 ILE A CG2 1 
ATOM   3312 C CD1 . ILE A 1 446 ? 148.345 149.806 143.417 1.00 122.29 ? 447 ILE A CD1 1 
ATOM   3313 N N   . ALA A 1 447 ? 152.894 148.555 145.190 1.00 111.25 ? 448 ALA A N   1 
ATOM   3314 C CA  . ALA A 1 447 ? 153.311 147.981 146.463 1.00 111.05 ? 448 ALA A CA  1 
ATOM   3315 C C   . ALA A 1 447 ? 153.382 149.047 147.547 1.00 114.45 ? 448 ALA A C   1 
ATOM   3316 O O   . ALA A 1 447 ? 153.231 148.742 148.735 1.00 116.74 ? 448 ALA A O   1 
ATOM   3317 C CB  . ALA A 1 447 ? 154.661 147.287 146.309 1.00 111.66 ? 448 ALA A CB  1 
ATOM   3318 N N   . PHE A 1 448 ? 153.623 150.300 147.156 1.00 115.77 ? 449 PHE A N   1 
ATOM   3319 C CA  . PHE A 1 448 ? 153.680 151.389 148.124 1.00 119.17 ? 449 PHE A CA  1 
ATOM   3320 C C   . PHE A 1 448 ? 152.287 151.756 148.623 1.00 115.60 ? 449 PHE A C   1 
ATOM   3321 O O   . PHE A 1 448 ? 152.126 152.169 149.777 1.00 114.87 ? 449 PHE A O   1 
ATOM   3322 C CB  . PHE A 1 448 ? 154.363 152.604 147.496 1.00 118.44 ? 449 PHE A CB  1 
ATOM   3323 C CG  . PHE A 1 448 ? 154.710 153.691 148.477 1.00 120.42 ? 449 PHE A CG  1 
ATOM   3324 C CD1 . PHE A 1 448 ? 155.063 153.386 149.785 1.00 123.64 ? 449 PHE A CD1 1 
ATOM   3325 C CD2 . PHE A 1 448 ? 154.677 155.021 148.089 1.00 119.53 ? 449 PHE A CD2 1 
ATOM   3326 C CE1 . PHE A 1 448 ? 155.379 154.389 150.684 1.00 126.06 ? 449 PHE A CE1 1 
ATOM   3327 C CE2 . PHE A 1 448 ? 154.992 156.028 148.982 1.00 127.49 ? 449 PHE A CE2 1 
ATOM   3328 C CZ  . PHE A 1 448 ? 155.343 155.711 150.282 1.00 130.75 ? 449 PHE A CZ  1 
ATOM   3329 N N   . VAL A 1 449 ? 151.272 151.622 147.766 1.00 114.64 ? 450 VAL A N   1 
ATOM   3330 C CA  . VAL A 1 449 ? 149.909 151.979 148.151 1.00 113.67 ? 450 VAL A CA  1 
ATOM   3331 C C   . VAL A 1 449 ? 149.356 150.980 149.159 1.00 118.20 ? 450 VAL A C   1 
ATOM   3332 O O   . VAL A 1 449 ? 148.720 151.362 150.148 1.00 124.24 ? 450 VAL A O   1 
ATOM   3333 C CB  . VAL A 1 449 ? 149.011 152.085 146.906 1.00 113.68 ? 450 VAL A CB  1 
ATOM   3334 C CG1 . VAL A 1 449 ? 147.617 152.561 147.287 1.00 116.83 ? 450 VAL A CG1 1 
ATOM   3335 C CG2 . VAL A 1 449 ? 149.632 153.027 145.896 1.00 117.22 ? 450 VAL A CG2 1 
ATOM   3336 N N   . ILE A 1 450 ? 149.595 149.687 148.926 1.00 112.83 ? 451 ILE A N   1 
ATOM   3337 C CA  . ILE A 1 450 ? 149.129 148.655 149.848 1.00 111.19 ? 451 ILE A CA  1 
ATOM   3338 C C   . ILE A 1 450 ? 149.908 148.724 151.160 1.00 117.21 ? 451 ILE A C   1 
ATOM   3339 O O   . ILE A 1 450 ? 149.356 148.484 152.242 1.00 119.57 ? 451 ILE A O   1 
ATOM   3340 C CB  . ILE A 1 450 ? 149.220 147.276 149.164 1.00 115.36 ? 451 ILE A CB  1 
ATOM   3341 C CG1 . ILE A 1 450 ? 148.214 147.209 148.017 1.00 125.92 ? 451 ILE A CG1 1 
ATOM   3342 C CG2 . ILE A 1 450 ? 148.902 146.132 150.117 1.00 118.30 ? 451 ILE A CG2 1 
ATOM   3343 C CD1 . ILE A 1 450 ? 146.784 147.472 148.454 1.00 129.07 ? 451 ILE A CD1 1 
ATOM   3344 N N   . ASN A 1 451 ? 151.191 149.093 151.085 1.00 118.05 ? 452 ASN A N   1 
ATOM   3345 C CA  . ASN A 1 451 ? 151.973 149.373 152.287 1.00 115.85 ? 452 ASN A CA  1 
ATOM   3346 C C   . ASN A 1 451 ? 151.398 150.571 153.037 1.00 116.44 ? 452 ASN A C   1 
ATOM   3347 O O   . ASN A 1 451 ? 151.316 150.566 154.271 1.00 118.89 ? 452 ASN A O   1 
ATOM   3348 C CB  . ASN A 1 451 ? 153.435 149.622 151.899 1.00 120.47 ? 452 ASN A CB  1 
ATOM   3349 C CG  . ASN A 1 451 ? 154.387 149.663 153.095 1.00 127.55 ? 452 ASN A CG  1 
ATOM   3350 O OD1 . ASN A 1 451 ? 153.989 149.512 154.250 1.00 126.47 ? 452 ASN A OD1 1 
ATOM   3351 N ND2 . ASN A 1 451 ? 155.666 149.873 152.807 1.00 125.53 ? 452 ASN A ND2 1 
ATOM   3352 N N   . SER A 1 452 ? 150.978 151.603 152.303 1.00 116.77 ? 453 SER A N   1 
ATOM   3353 C CA  . SER A 1 452 ? 150.421 152.791 152.942 1.00 113.04 ? 453 SER A CA  1 
ATOM   3354 C C   . SER A 1 452 ? 149.010 152.539 153.461 1.00 116.69 ? 453 SER A C   1 
ATOM   3355 O O   . SER A 1 452 ? 148.648 153.014 154.542 1.00 118.21 ? 453 SER A O   1 
ATOM   3356 C CB  . SER A 1 452 ? 150.433 153.967 151.969 1.00 113.57 ? 453 SER A CB  1 
ATOM   3357 O OG  . SER A 1 452 ? 151.751 154.446 151.771 1.00 121.29 ? 453 SER A OG  1 
ATOM   3358 N N   . LEU A 1 453 ? 148.193 151.804 152.697 1.00 115.59 ? 454 LEU A N   1 
ATOM   3359 C CA  . LEU A 1 453 ? 146.806 151.569 153.098 1.00 113.89 ? 454 LEU A CA  1 
ATOM   3360 C C   . LEU A 1 453 ? 146.719 150.660 154.318 1.00 113.54 ? 454 LEU A C   1 
ATOM   3361 O O   . LEU A 1 453 ? 145.883 150.877 155.203 1.00 117.52 ? 454 LEU A O   1 
ATOM   3362 C CB  . LEU A 1 453 ? 146.013 150.974 151.934 1.00 124.43 ? 454 LEU A CB  1 
ATOM   3363 C CG  . LEU A 1 453 ? 144.520 150.720 152.158 1.00 134.25 ? 454 LEU A CG  1 
ATOM   3364 C CD1 . LEU A 1 453 ? 143.783 152.025 152.424 1.00 130.38 ? 454 LEU A CD1 1 
ATOM   3365 C CD2 . LEU A 1 453 ? 143.915 149.991 150.968 1.00 128.28 ? 454 LEU A CD2 1 
ATOM   3366 N N   . SER A 1 454 ? 147.572 149.635 154.384 1.00 111.66 ? 455 SER A N   1 
ATOM   3367 C CA  . SER A 1 454 ? 147.564 148.750 155.543 1.00 111.88 ? 455 SER A CA  1 
ATOM   3368 C C   . SER A 1 454 ? 148.190 149.407 156.764 1.00 114.78 ? 455 SER A C   1 
ATOM   3369 O O   . SER A 1 454 ? 147.922 148.985 157.895 1.00 118.29 ? 455 SER A O   1 
ATOM   3370 C CB  . SER A 1 454 ? 148.289 147.446 155.222 1.00 118.99 ? 455 SER A CB  1 
ATOM   3371 O OG  . SER A 1 454 ? 147.926 146.434 156.143 1.00 120.25 ? 455 SER A OG  1 
ATOM   3372 N N   . SER A 1 455 ? 149.034 150.420 156.560 1.00 111.01 ? 456 SER A N   1 
ATOM   3373 C CA  . SER A 1 455 ? 149.626 151.128 157.689 1.00 114.38 ? 456 SER A CA  1 
ATOM   3374 C C   . SER A 1 455 ? 148.587 151.961 158.426 1.00 123.90 ? 456 SER A C   1 
ATOM   3375 O O   . SER A 1 455 ? 148.608 152.044 159.659 1.00 126.99 ? 456 SER A O   1 
ATOM   3376 C CB  . SER A 1 455 ? 150.776 152.012 157.211 1.00 114.80 ? 456 SER A CB  1 
ATOM   3377 O OG  . SER A 1 455 ? 151.826 151.233 156.666 1.00 119.51 ? 456 SER A OG  1 
ATOM   3378 N N   . CYS A 1 456 ? 147.675 152.596 157.686 1.00 120.85 ? 457 CYS A N   1 
ATOM   3379 C CA  . CYS A 1 456 ? 146.657 153.425 158.321 1.00 115.38 ? 457 CYS A CA  1 
ATOM   3380 C C   . CYS A 1 456 ? 145.565 152.592 158.982 1.00 118.69 ? 457 CYS A C   1 
ATOM   3381 O O   . CYS A 1 456 ? 144.916 153.065 159.921 1.00 127.46 ? 457 CYS A O   1 
ATOM   3382 C CB  . CYS A 1 456 ? 146.053 154.390 157.304 1.00 124.85 ? 457 CYS A CB  1 
ATOM   3383 S SG  . CYS A 1 456 ? 147.249 155.304 156.310 1.00 143.78 ? 457 CYS A SG  1 
ATOM   3384 N N   . PHE A 1 457 ? 145.339 151.366 158.508 1.00 115.58 ? 458 PHE A N   1 
ATOM   3385 C CA  . PHE A 1 457 ? 144.359 150.497 159.152 1.00 118.11 ? 458 PHE A CA  1 
ATOM   3386 C C   . PHE A 1 457 ? 144.882 149.967 160.483 1.00 122.04 ? 458 PHE A C   1 
ATOM   3387 O O   . PHE A 1 457 ? 144.142 149.928 161.472 1.00 123.61 ? 458 PHE A O   1 
ATOM   3388 C CB  . PHE A 1 457 ? 143.992 149.337 158.224 1.00 120.03 ? 458 PHE A CB  1 
ATOM   3389 C CG  . PHE A 1 457 ? 142.822 148.511 158.701 1.00 126.70 ? 458 PHE A CG  1 
ATOM   3390 C CD1 . PHE A 1 457 ? 141.795 149.082 159.441 1.00 128.21 ? 458 PHE A CD1 1 
ATOM   3391 C CD2 . PHE A 1 457 ? 142.758 147.156 158.414 1.00 129.19 ? 458 PHE A CD2 1 
ATOM   3392 C CE1 . PHE A 1 457 ? 140.728 148.320 159.878 1.00 127.58 ? 458 PHE A CE1 1 
ATOM   3393 C CE2 . PHE A 1 457 ? 141.694 146.388 158.849 1.00 130.16 ? 458 PHE A CE2 1 
ATOM   3394 C CZ  . PHE A 1 457 ? 140.678 146.972 159.582 1.00 125.71 ? 458 PHE A CZ  1 
ATOM   3395 N N   . GLY A 1 458 ? 146.151 149.563 160.529 1.00 120.34 ? 459 GLY A N   1 
ATOM   3396 C CA  . GLY A 1 458 ? 146.724 149.006 161.739 1.00 120.17 ? 459 GLY A CA  1 
ATOM   3397 C C   . GLY A 1 458 ? 147.043 150.008 162.824 1.00 128.00 ? 459 GLY A C   1 
ATOM   3398 O O   . GLY A 1 458 ? 147.315 149.605 163.958 1.00 134.40 ? 459 GLY A O   1 
ATOM   3399 N N   . PHE A 1 459 ? 147.025 151.303 162.503 1.00 127.44 ? 460 PHE A N   1 
ATOM   3400 C CA  . PHE A 1 459 ? 147.271 152.320 163.519 1.00 130.11 ? 460 PHE A CA  1 
ATOM   3401 C C   . PHE A 1 459 ? 146.085 152.469 164.462 1.00 133.41 ? 460 PHE A C   1 
ATOM   3402 O O   . PHE A 1 459 ? 146.266 152.675 165.667 1.00 138.80 ? 460 PHE A O   1 
ATOM   3403 C CB  . PHE A 1 459 ? 147.595 153.655 162.852 1.00 138.21 ? 460 PHE A CB  1 
ATOM   3404 C CG  . PHE A 1 459 ? 147.880 154.762 163.822 1.00 145.18 ? 460 PHE A CG  1 
ATOM   3405 C CD1 . PHE A 1 459 ? 149.086 154.815 164.496 1.00 143.64 ? 460 PHE A CD1 1 
ATOM   3406 C CD2 . PHE A 1 459 ? 146.943 155.759 164.051 1.00 148.73 ? 460 PHE A CD2 1 
ATOM   3407 C CE1 . PHE A 1 459 ? 149.352 155.834 165.390 1.00 149.52 ? 460 PHE A CE1 1 
ATOM   3408 C CE2 . PHE A 1 459 ? 147.203 156.780 164.942 1.00 151.97 ? 460 PHE A CE2 1 
ATOM   3409 C CZ  . PHE A 1 459 ? 148.409 156.817 165.612 1.00 154.58 ? 460 PHE A CZ  1 
ATOM   3410 N N   . LEU A 1 460 ? 144.863 152.374 163.934 1.00 132.90 ? 461 LEU A N   1 
ATOM   3411 C CA  . LEU A 1 460 ? 143.676 152.636 164.737 1.00 133.58 ? 461 LEU A CA  1 
ATOM   3412 C C   . LEU A 1 460 ? 143.322 151.501 165.687 1.00 136.19 ? 461 LEU A C   1 
ATOM   3413 O O   . LEU A 1 460 ? 142.502 151.710 166.585 1.00 145.45 ? 461 LEU A O   1 
ATOM   3414 C CB  . LEU A 1 460 ? 142.478 152.923 163.832 1.00 131.57 ? 461 LEU A CB  1 
ATOM   3415 C CG  . LEU A 1 460 ? 142.397 154.320 163.222 1.00 131.49 ? 461 LEU A CG  1 
ATOM   3416 C CD1 . LEU A 1 460 ? 141.199 154.421 162.298 1.00 136.45 ? 461 LEU A CD1 1 
ATOM   3417 C CD2 . LEU A 1 460 ? 142.329 155.375 164.311 1.00 142.78 ? 461 LEU A CD2 1 
ATOM   3418 N N   . ASP A 1 461 ? 143.952 150.352 165.581 1.00 132.72 ? 462 ASP A N   1 
ATOM   3419 C CA  . ASP A 1 461 ? 143.571 149.205 166.403 1.00 140.23 ? 462 ASP A CA  1 
ATOM   3420 C C   . ASP A 1 461 ? 144.095 149.320 167.831 1.00 145.46 ? 462 ASP A C   1 
ATOM   3421 O O   . ASP A 1 461 ? 143.322 149.052 168.768 1.00 156.72 ? 462 ASP A O   1 
ATOM   3422 C CB  . ASP A 1 461 ? 144.001 147.903 165.716 1.00 141.81 ? 462 ASP A CB  1 
ATOM   3423 C CG  . ASP A 1 461 ? 143.185 147.605 164.475 1.00 143.50 ? 462 ASP A CG  1 
ATOM   3424 O OD1 . ASP A 1 461 ? 142.792 148.563 163.778 1.00 138.44 ? 462 ASP A OD1 1 
ATOM   3425 O OD2 . ASP A 1 461 ? 142.940 146.412 164.195 1.00 145.62 ? 462 ASP A OD2 1 
ATOM   3426 N N   . PRO A 1 462 ? 145.349 149.701 168.008 1.00 138.02 ? 463 PRO A N   1 
ATOM   3427 C CA  . PRO A 1 462 ? 145.754 149.977 169.396 1.00 140.22 ? 463 PRO A CA  1 
ATOM   3428 C C   . PRO A 1 462 ? 145.448 151.382 169.894 1.00 147.38 ? 463 PRO A C   1 
ATOM   3429 O O   . PRO A 1 462 ? 145.346 151.570 171.114 1.00 151.77 ? 463 PRO A O   1 
ATOM   3430 C CB  . PRO A 1 462 ? 147.274 149.761 169.372 1.00 145.43 ? 463 PRO A CB  1 
ATOM   3431 C CG  . PRO A 1 462 ? 147.540 148.943 168.201 1.00 143.41 ? 463 PRO A CG  1 
ATOM   3432 C CD  . PRO A 1 462 ? 146.549 149.414 167.194 1.00 140.15 ? 463 PRO A CD  1 
ATOM   3433 N N   . THR A 1 463 ? 145.304 152.373 169.011 1.00 148.95 ? 464 THR A N   1 
ATOM   3434 C CA  . THR A 1 463 ? 145.422 153.767 169.416 1.00 154.71 ? 464 THR A CA  1 
ATOM   3435 C C   . THR A 1 463 ? 144.129 154.572 169.401 1.00 159.85 ? 464 THR A C   1 
ATOM   3436 O O   . THR A 1 463 ? 144.116 155.673 169.961 1.00 164.44 ? 464 THR A O   1 
ATOM   3437 C CB  . THR A 1 463 ? 146.444 154.498 168.529 1.00 157.37 ? 464 THR A CB  1 
ATOM   3438 O OG1 . THR A 1 463 ? 145.930 154.606 167.196 1.00 153.41 ? 464 THR A OG1 1 
ATOM   3439 C CG2 . THR A 1 463 ? 147.767 153.745 168.503 1.00 152.92 ? 464 THR A CG2 1 
ATOM   3440 N N   . LEU A 1 464 ? 143.055 154.081 168.777 1.00 156.08 ? 465 LEU A N   1 
ATOM   3441 C CA  . LEU A 1 464 ? 141.826 154.870 168.734 1.00 163.07 ? 465 LEU A CA  1 
ATOM   3442 C C   . LEU A 1 464 ? 141.120 154.860 170.084 1.00 171.48 ? 465 LEU A C   1 
ATOM   3443 O O   . LEU A 1 464 ? 140.580 155.886 170.516 1.00 175.46 ? 465 LEU A O   1 
ATOM   3444 C CB  . LEU A 1 464 ? 140.900 154.353 167.631 1.00 162.28 ? 465 LEU A CB  1 
ATOM   3445 C CG  . LEU A 1 464 ? 139.423 154.758 167.645 1.00 165.03 ? 465 LEU A CG  1 
ATOM   3446 C CD1 . LEU A 1 464 ? 139.268 156.238 167.327 1.00 163.84 ? 465 LEU A CD1 1 
ATOM   3447 C CD2 . LEU A 1 464 ? 138.630 153.920 166.660 1.00 158.98 ? 465 LEU A CD2 1 
ATOM   3448 N N   . SER A 1 465 ? 141.134 153.715 170.772 1.00 169.99 ? 466 SER A N   1 
ATOM   3449 C CA  . SER A 1 465 ? 140.465 153.602 172.066 1.00 170.47 ? 466 SER A CA  1 
ATOM   3450 C C   . SER A 1 465 ? 141.179 154.414 173.141 1.00 165.64 ? 466 SER A C   1 
ATOM   3451 O O   . SER A 1 465 ? 140.538 154.923 174.067 1.00 164.02 ? 466 SER A O   1 
ATOM   3452 C CB  . SER A 1 465 ? 140.373 152.133 172.479 1.00 172.12 ? 466 SER A CB  1 
ATOM   3453 O OG  . SER A 1 465 ? 141.653 151.524 172.497 1.00 161.07 ? 466 SER A OG  1 
ATOM   3454 N N   . LEU A 1 466 ? 142.503 154.546 173.034 1.00 164.44 ? 467 LEU A N   1 
ATOM   3455 C CA  . LEU A 1 466 ? 143.258 155.272 174.050 1.00 168.40 ? 467 LEU A CA  1 
ATOM   3456 C C   . LEU A 1 466 ? 143.078 156.780 173.901 1.00 172.83 ? 467 LEU A C   1 
ATOM   3457 O O   . LEU A 1 466 ? 143.125 157.519 174.892 1.00 174.88 ? 467 LEU A O   1 
ATOM   3458 C CB  . LEU A 1 466 ? 144.734 154.877 173.975 1.00 170.28 ? 467 LEU A CB  1 
ATOM   3459 C CG  . LEU A 1 466 ? 145.704 155.455 175.006 1.00 174.19 ? 467 LEU A CG  1 
ATOM   3460 C CD1 . LEU A 1 466 ? 145.310 155.017 176.405 1.00 170.52 ? 467 LEU A CD1 1 
ATOM   3461 C CD2 . LEU A 1 466 ? 147.123 155.015 174.695 1.00 177.22 ? 467 LEU A CD2 1 
ATOM   3462 N N   . PHE A 1 467 ? 142.873 157.255 172.668 1.00 172.19 ? 468 PHE A N   1 
ATOM   3463 C CA  . PHE A 1 467 ? 142.551 158.665 172.455 1.00 175.24 ? 468 PHE A CA  1 
ATOM   3464 C C   . PHE A 1 467 ? 141.177 159.012 173.016 1.00 174.99 ? 468 PHE A C   1 
ATOM   3465 O O   . PHE A 1 467 ? 140.987 160.093 173.586 1.00 178.11 ? 468 PHE A O   1 
ATOM   3466 C CB  . PHE A 1 467 ? 142.631 159.000 170.963 1.00 176.15 ? 468 PHE A CB  1 
ATOM   3467 C CG  . PHE A 1 467 ? 141.909 160.268 170.577 1.00 176.62 ? 468 PHE A CG  1 
ATOM   3468 C CD1 . PHE A 1 467 ? 142.461 161.508 170.857 1.00 173.56 ? 468 PHE A CD1 1 
ATOM   3469 C CD2 . PHE A 1 467 ? 140.698 160.216 169.896 1.00 175.35 ? 468 PHE A CD2 1 
ATOM   3470 C CE1 . PHE A 1 467 ? 141.807 162.672 170.496 1.00 171.49 ? 468 PHE A CE1 1 
ATOM   3471 C CE2 . PHE A 1 467 ? 140.039 161.378 169.533 1.00 172.30 ? 468 PHE A CE2 1 
ATOM   3472 C CZ  . PHE A 1 467 ? 140.596 162.606 169.832 1.00 171.10 ? 468 PHE A CZ  1 
ATOM   3473 N N   . VAL A 1 468 ? 140.203 158.115 172.844 1.00 172.16 ? 469 VAL A N   1 
ATOM   3474 C CA  . VAL A 1 468 ? 138.869 158.327 173.400 1.00 177.08 ? 469 VAL A CA  1 
ATOM   3475 C C   . VAL A 1 468 ? 138.913 158.266 174.926 1.00 179.14 ? 469 VAL A C   1 
ATOM   3476 O O   . VAL A 1 468 ? 138.202 159.009 175.615 1.00 178.94 ? 469 VAL A O   1 
ATOM   3477 C CB  . VAL A 1 468 ? 137.886 157.302 172.795 1.00 177.29 ? 469 VAL A CB  1 
ATOM   3478 C CG1 . VAL A 1 468 ? 136.494 157.403 173.414 1.00 179.20 ? 469 VAL A CG1 1 
ATOM   3479 C CG2 . VAL A 1 468 ? 137.796 157.496 171.290 1.00 172.99 ? 469 VAL A CG2 1 
ATOM   3480 N N   . LEU A 1 469 ? 139.775 157.404 175.474 1.00 177.53 ? 470 LEU A N   1 
ATOM   3481 C CA  . LEU A 1 469 ? 139.893 157.271 176.925 1.00 175.33 ? 470 LEU A CA  1 
ATOM   3482 C C   . LEU A 1 469 ? 140.460 158.535 177.565 1.00 176.19 ? 470 LEU A C   1 
ATOM   3483 O O   . LEU A 1 469 ? 140.004 158.953 178.635 1.00 179.53 ? 470 LEU A O   1 
ATOM   3484 C CB  . LEU A 1 469 ? 140.763 156.061 177.265 1.00 175.21 ? 470 LEU A CB  1 
ATOM   3485 C CG  . LEU A 1 469 ? 140.972 155.740 178.747 1.00 174.16 ? 470 LEU A CG  1 
ATOM   3486 C CD1 . LEU A 1 469 ? 139.703 155.166 179.359 1.00 173.96 ? 470 LEU A CD1 1 
ATOM   3487 C CD2 . LEU A 1 469 ? 142.139 154.782 178.927 1.00 174.32 ? 470 LEU A CD2 1 
ATOM   3488 N N   . GLU A 1 470 ? 141.446 159.162 176.923 1.00 178.41 ? 471 GLU A N   1 
ATOM   3489 C CA  . GLU A 1 470 ? 142.060 160.356 177.494 1.00 183.74 ? 471 GLU A CA  1 
ATOM   3490 C C   . GLU A 1 470 ? 141.277 161.631 177.202 1.00 183.65 ? 471 GLU A C   1 
ATOM   3491 O O   . GLU A 1 470 ? 141.529 162.653 177.849 1.00 182.12 ? 471 GLU A O   1 
ATOM   3492 C CB  . GLU A 1 470 ? 143.496 160.508 176.985 1.00 182.72 ? 471 GLU A CB  1 
ATOM   3493 C CG  . GLU A 1 470 ? 143.605 160.878 175.515 1.00 179.74 ? 471 GLU A CG  1 
ATOM   3494 C CD  . GLU A 1 470 ? 144.877 160.357 174.876 1.00 178.16 ? 471 GLU A CD  1 
ATOM   3495 O OE1 . GLU A 1 470 ? 145.636 159.636 175.557 1.00 176.64 ? 471 GLU A OE1 1 
ATOM   3496 O OE2 . GLU A 1 470 ? 145.118 160.669 173.691 1.00 179.91 ? 471 GLU A OE2 1 
ATOM   3497 N N   . LYS A 1 471 ? 140.343 161.603 176.253 1.00 181.76 ? 472 LYS A N   1 
ATOM   3498 C CA  . LYS A 1 471 ? 139.560 162.781 175.900 1.00 177.83 ? 472 LYS A CA  1 
ATOM   3499 C C   . LYS A 1 471 ? 138.079 162.631 176.207 1.00 182.24 ? 472 LYS A C   1 
ATOM   3500 O O   . LYS A 1 471 ? 137.512 163.451 176.936 1.00 184.72 ? 472 LYS A O   1 
ATOM   3501 C CB  . LYS A 1 471 ? 139.744 163.111 174.412 1.00 173.49 ? 472 LYS A CB  1 
ATOM   3502 C CG  . LYS A 1 471 ? 139.445 164.558 174.063 1.00 175.63 ? 472 LYS A CG  1 
ATOM   3503 C CD  . LYS A 1 471 ? 140.034 164.938 172.716 1.00 182.53 ? 472 LYS A CD  1 
ATOM   3504 C CE  . LYS A 1 471 ? 139.870 166.423 172.436 1.00 185.47 ? 472 LYS A CE  1 
ATOM   3505 N NZ  . LYS A 1 471 ? 140.559 166.830 171.180 1.00 177.21 ? 472 LYS A NZ  1 
ATOM   3506 N N   . PHE A 1 472 ? 137.432 161.596 175.671 1.00 185.13 ? 473 PHE A N   1 
ATOM   3507 C CA  . PHE A 1 472 ? 135.993 161.421 175.834 1.00 181.63 ? 473 PHE A CA  1 
ATOM   3508 C C   . PHE A 1 472 ? 135.643 160.503 176.996 1.00 183.47 ? 473 PHE A C   1 
ATOM   3509 O O   . PHE A 1 472 ? 134.494 160.531 177.457 1.00 180.52 ? 473 PHE A O   1 
ATOM   3510 C CB  . PHE A 1 472 ? 135.373 160.866 174.543 1.00 173.42 ? 473 PHE A CB  1 
ATOM   3511 C CG  . PHE A 1 472 ? 135.550 161.758 173.334 1.00 178.80 ? 473 PHE A CG  1 
ATOM   3512 C CD1 . PHE A 1 472 ? 135.733 163.132 173.465 1.00 175.77 ? 473 PHE A CD1 1 
ATOM   3513 C CD2 . PHE A 1 472 ? 135.553 161.208 172.060 1.00 180.66 ? 473 PHE A CD2 1 
ATOM   3514 C CE1 . PHE A 1 472 ? 135.903 163.935 172.350 1.00 176.12 ? 473 PHE A CE1 1 
ATOM   3515 C CE2 . PHE A 1 472 ? 135.722 162.006 170.940 1.00 175.30 ? 473 PHE A CE2 1 
ATOM   3516 C CZ  . PHE A 1 472 ? 135.899 163.370 171.086 1.00 174.59 ? 473 PHE A CZ  1 
ATOM   3517 N N   . ASN A 1 473 ? 136.610 159.699 177.459 1.00 183.26 ? 474 ASN A N   1 
ATOM   3518 C CA  . ASN A 1 473 ? 136.519 158.829 178.638 1.00 180.74 ? 474 ASN A CA  1 
ATOM   3519 C C   . ASN A 1 473 ? 135.380 157.812 178.493 1.00 181.15 ? 474 ASN A C   1 
ATOM   3520 O O   . ASN A 1 473 ? 134.366 157.848 179.194 1.00 184.71 ? 474 ASN A O   1 
ATOM   3521 C CB  . ASN A 1 473 ? 136.379 159.658 179.924 1.00 183.98 ? 474 ASN A CB  1 
ATOM   3522 C CG  . ASN A 1 473 ? 136.537 158.821 181.181 1.00 184.78 ? 474 ASN A CG  1 
ATOM   3523 O OD1 . ASN A 1 473 ? 137.601 158.258 181.436 1.00 184.20 ? 474 ASN A OD1 1 
ATOM   3524 N ND2 . ASN A 1 473 ? 135.474 158.736 181.972 1.00 182.52 ? 474 ASN A ND2 1 
ATOM   3525 N N   . LEU A 1 474 ? 135.570 156.908 177.539 1.00 178.03 ? 475 LEU A N   1 
ATOM   3526 C CA  . LEU A 1 474 ? 134.608 155.848 177.290 1.00 180.96 ? 475 LEU A CA  1 
ATOM   3527 C C   . LEU A 1 474 ? 135.266 154.489 177.472 1.00 175.45 ? 475 LEU A C   1 
ATOM   3528 O O   . LEU A 1 474 ? 136.465 154.338 177.213 1.00 170.01 ? 475 LEU A O   1 
ATOM   3529 C CB  . LEU A 1 474 ? 134.017 155.953 175.875 1.00 182.89 ? 475 LEU A CB  1 
ATOM   3530 C CG  . LEU A 1 474 ? 133.029 157.100 175.649 1.00 178.51 ? 475 LEU A CG  1 
ATOM   3531 C CD1 . LEU A 1 474 ? 132.649 157.198 174.179 1.00 177.82 ? 475 LEU A CD1 1 
ATOM   3532 C CD2 . LEU A 1 474 ? 131.792 156.932 176.522 1.00 163.29 ? 475 LEU A CD2 1 
ATOM   3533 N N   . PRO A 1 475 ? 134.512 153.488 177.940 1.00 176.17 ? 476 PRO A N   1 
ATOM   3534 C CA  . PRO A 1 475 ? 135.078 152.141 178.082 1.00 176.54 ? 476 PRO A CA  1 
ATOM   3535 C C   . PRO A 1 475 ? 135.371 151.510 176.729 1.00 175.55 ? 476 PRO A C   1 
ATOM   3536 O O   . PRO A 1 475 ? 134.737 151.830 175.723 1.00 171.68 ? 476 PRO A O   1 
ATOM   3537 C CB  . PRO A 1 475 ? 133.983 151.369 178.828 1.00 180.03 ? 476 PRO A CB  1 
ATOM   3538 C CG  . PRO A 1 475 ? 133.137 152.414 179.469 1.00 181.55 ? 476 PRO A CG  1 
ATOM   3539 C CD  . PRO A 1 475 ? 133.170 153.583 178.539 1.00 177.12 ? 476 PRO A CD  1 
ATOM   3540 N N   . ALA A 1 476 ? 136.342 150.589 176.727 1.00 181.39 ? 477 ALA A N   1 
ATOM   3541 C CA  . ALA A 1 476 ? 136.807 149.982 175.481 1.00 181.26 ? 477 ALA A CA  1 
ATOM   3542 C C   . ALA A 1 476 ? 135.755 149.062 174.872 1.00 175.97 ? 477 ALA A C   1 
ATOM   3543 O O   . ALA A 1 476 ? 135.776 148.802 173.662 1.00 172.27 ? 477 ALA A O   1 
ATOM   3544 C CB  . ALA A 1 476 ? 138.108 149.217 175.726 1.00 182.61 ? 477 ALA A CB  1 
ATOM   3545 N N   . GLY A 1 477 ? 134.840 148.544 175.696 1.00 174.13 ? 478 GLY A N   1 
ATOM   3546 C CA  . GLY A 1 477 ? 133.704 147.810 175.161 1.00 173.55 ? 478 GLY A CA  1 
ATOM   3547 C C   . GLY A 1 477 ? 132.771 148.693 174.354 1.00 173.17 ? 478 GLY A C   1 
ATOM   3548 O O   . GLY A 1 477 ? 132.160 148.243 173.381 1.00 175.87 ? 478 GLY A O   1 
ATOM   3549 N N   . TYR A 1 478 ? 132.646 149.963 174.750 1.00 168.92 ? 479 TYR A N   1 
ATOM   3550 C CA  . TYR A 1 478 ? 131.865 150.911 173.965 1.00 167.19 ? 479 TYR A CA  1 
ATOM   3551 C C   . TYR A 1 478 ? 132.602 151.306 172.690 1.00 160.75 ? 479 TYR A C   1 
ATOM   3552 O O   . TYR A 1 478 ? 131.968 151.661 171.690 1.00 153.41 ? 479 TYR A O   1 
ATOM   3553 C CB  . TYR A 1 478 ? 131.540 152.139 174.819 1.00 169.38 ? 479 TYR A CB  1 
ATOM   3554 C CG  . TYR A 1 478 ? 130.272 152.873 174.433 1.00 159.49 ? 479 TYR A CG  1 
ATOM   3555 C CD1 . TYR A 1 478 ? 130.249 153.762 173.364 1.00 155.48 ? 479 TYR A CD1 1 
ATOM   3556 C CD2 . TYR A 1 478 ? 129.094 152.676 175.147 1.00 148.52 ? 479 TYR A CD2 1 
ATOM   3557 C CE1 . TYR A 1 478 ? 129.089 154.432 173.018 1.00 157.28 ? 479 TYR A CE1 1 
ATOM   3558 C CE2 . TYR A 1 478 ? 127.932 153.339 174.809 1.00 143.87 ? 479 TYR A CE2 1 
ATOM   3559 C CZ  . TYR A 1 478 ? 127.935 154.215 173.745 1.00 156.40 ? 479 TYR A CZ  1 
ATOM   3560 O OH  . TYR A 1 478 ? 126.777 154.878 173.406 1.00 162.46 ? 479 TYR A OH  1 
ATOM   3561 N N   . VAL A 1 479 ? 133.938 151.229 172.702 1.00 163.67 ? 480 VAL A N   1 
ATOM   3562 C CA  . VAL A 1 479 ? 134.734 151.457 171.500 1.00 160.49 ? 480 VAL A CA  1 
ATOM   3563 C C   . VAL A 1 479 ? 134.642 150.249 170.561 1.00 156.82 ? 480 VAL A C   1 
ATOM   3564 O O   . VAL A 1 479 ? 134.953 150.355 169.368 1.00 153.77 ? 480 VAL A O   1 
ATOM   3565 C CB  . VAL A 1 479 ? 136.182 151.807 171.927 1.00 161.09 ? 480 VAL A CB  1 
ATOM   3566 C CG1 . VAL A 1 479 ? 137.072 152.241 170.754 1.00 161.32 ? 480 VAL A CG1 1 
ATOM   3567 C CG2 . VAL A 1 479 ? 136.172 152.904 172.976 1.00 167.70 ? 480 VAL A CG2 1 
ATOM   3568 N N   . GLY A 1 480 ? 134.169 149.103 171.062 1.00 156.29 ? 481 GLY A N   1 
ATOM   3569 C CA  . GLY A 1 480 ? 133.908 147.969 170.190 1.00 151.56 ? 481 GLY A CA  1 
ATOM   3570 C C   . GLY A 1 480 ? 132.795 148.219 169.190 1.00 146.19 ? 481 GLY A C   1 
ATOM   3571 O O   . GLY A 1 480 ? 132.774 147.615 168.116 1.00 143.82 ? 481 GLY A O   1 
ATOM   3572 N N   . LEU A 1 481 ? 131.860 149.115 169.522 1.00 147.33 ? 482 LEU A N   1 
ATOM   3573 C CA  . LEU A 1 481 ? 130.839 149.516 168.559 1.00 146.04 ? 482 LEU A CA  1 
ATOM   3574 C C   . LEU A 1 481 ? 131.426 150.407 167.470 1.00 139.67 ? 482 LEU A C   1 
ATOM   3575 O O   . LEU A 1 481 ? 130.884 150.470 166.360 1.00 134.51 ? 482 LEU A O   1 
ATOM   3576 C CB  . LEU A 1 481 ? 129.688 150.214 169.298 1.00 154.54 ? 482 LEU A CB  1 
ATOM   3577 C CG  . LEU A 1 481 ? 128.328 150.578 168.678 1.00 160.20 ? 482 LEU A CG  1 
ATOM   3578 C CD1 . LEU A 1 481 ? 127.303 150.683 169.793 1.00 160.04 ? 482 LEU A CD1 1 
ATOM   3579 C CD2 . LEU A 1 481 ? 128.332 151.893 167.901 1.00 152.94 ? 482 LEU A CD2 1 
ATOM   3580 N N   . VAL A 1 482 ? 132.524 151.104 167.771 1.00 141.68 ? 483 VAL A N   1 
ATOM   3581 C CA  . VAL A 1 482 ? 133.142 152.010 166.806 1.00 137.09 ? 483 VAL A CA  1 
ATOM   3582 C C   . VAL A 1 482 ? 133.806 151.224 165.677 1.00 137.38 ? 483 VAL A C   1 
ATOM   3583 O O   . VAL A 1 482 ? 133.757 151.630 164.508 1.00 138.38 ? 483 VAL A O   1 
ATOM   3584 C CB  . VAL A 1 482 ? 134.130 152.943 167.536 1.00 137.83 ? 483 VAL A CB  1 
ATOM   3585 C CG1 . VAL A 1 482 ? 134.851 153.871 166.577 1.00 142.81 ? 483 VAL A CG1 1 
ATOM   3586 C CG2 . VAL A 1 482 ? 133.408 153.739 168.614 1.00 139.88 ? 483 VAL A CG2 1 
ATOM   3587 N N   . PHE A 1 483 ? 134.395 150.231 166.032 1.00 137.74 ? 484 PHE A N   1 
ATOM   3588 C CA  . PHE A 1 483 ? 135.061 149.365 165.061 1.00 133.05 ? 484 PHE A CA  1 
ATOM   3589 C C   . PHE A 1 483 ? 134.065 148.730 164.098 1.00 131.90 ? 484 PHE A C   1 
ATOM   3590 O O   . PHE A 1 483 ? 134.330 148.627 162.894 1.00 134.56 ? 484 PHE A O   1 
ATOM   3591 C CB  . PHE A 1 483 ? 135.868 148.290 165.783 1.00 132.41 ? 484 PHE A CB  1 
ATOM   3592 C CG  . PHE A 1 483 ? 137.346 148.511 165.723 1.00 133.51 ? 484 PHE A CG  1 
ATOM   3593 C CD1 . PHE A 1 483 ? 137.892 149.723 166.105 1.00 134.51 ? 484 PHE A CD1 1 
ATOM   3594 C CD2 . PHE A 1 483 ? 138.188 147.516 165.263 1.00 133.10 ? 484 PHE A CD2 1 
ATOM   3595 C CE1 . PHE A 1 483 ? 139.251 149.932 166.045 1.00 138.44 ? 484 PHE A CE1 1 
ATOM   3596 C CE2 . PHE A 1 483 ? 139.548 147.720 165.199 1.00 132.98 ? 484 PHE A CE2 1 
ATOM   3597 C CZ  . PHE A 1 483 ? 140.080 148.930 165.591 1.00 137.31 ? 484 PHE A CZ  1 
ATOM   3598 N N   . LEU A 1 484 ? 132.801 148.325 164.551 1.00 130.94 ? 485 LEU A N   1 
ATOM   3599 C CA  . LEU A 1 484 ? 131.741 147.825 163.680 1.00 127.32 ? 485 LEU A CA  1 
ATOM   3600 C C   . LEU A 1 484 ? 131.188 148.919 162.776 1.00 127.13 ? 485 LEU A C   1 
ATOM   3601 O O   . LEU A 1 484 ? 130.568 148.616 161.750 1.00 126.29 ? 485 LEU A O   1 
ATOM   3602 C CB  . LEU A 1 484 ? 130.612 147.196 164.503 1.00 135.07 ? 485 LEU A CB  1 
ATOM   3603 C CG  . LEU A 1 484 ? 130.673 145.725 164.947 1.00 144.72 ? 485 LEU A CG  1 
ATOM   3604 C CD1 . LEU A 1 484 ? 130.651 144.811 163.729 1.00 145.39 ? 485 LEU A CD1 1 
ATOM   3605 C CD2 . LEU A 1 484 ? 131.860 145.388 165.843 1.00 141.45 ? 485 LEU A CD2 1 
ATOM   3606 N N   . GLY A 1 485 ? 131.379 150.187 163.145 1.00 129.34 ? 486 GLY A N   1 
ATOM   3607 C CA  . GLY A 1 485 ? 130.989 151.273 162.260 1.00 123.16 ? 486 GLY A CA  1 
ATOM   3608 C C   . GLY A 1 485 ? 131.839 151.338 161.006 1.00 121.89 ? 486 GLY A C   1 
ATOM   3609 O O   . GLY A 1 485 ? 131.333 151.600 159.913 1.00 125.14 ? 486 GLY A O   1 
ATOM   3610 N N   . MET A 1 486 ? 133.219 151.088 161.168 1.00 116.88 ? 487 MET A N   1 
ATOM   3611 C CA  . MET A 1 486 ? 134.092 151.076 159.998 1.00 120.79 ? 487 MET A CA  1 
ATOM   3612 C C   . MET A 1 486 ? 133.887 149.814 159.171 1.00 123.64 ? 487 MET A C   1 
ATOM   3613 O O   . MET A 1 486 ? 134.059 149.828 157.947 1.00 125.33 ? 487 MET A O   1 
ATOM   3614 C CB  . MET A 1 486 ? 135.553 151.201 160.427 1.00 123.33 ? 487 MET A CB  1 
ATOM   3615 C CG  . MET A 1 486 ? 136.434 151.945 159.434 1.00 132.67 ? 487 MET A CG  1 
ATOM   3616 S SD  . MET A 1 486 ? 138.102 151.265 159.326 1.00 137.14 ? 487 MET A SD  1 
ATOM   3617 C CE  . MET A 1 486 ? 137.953 150.223 157.877 1.00 134.21 ? 487 MET A CE  1 
ATOM   3618 N N   . ALA A 1 487 ? 133.543 148.677 159.816 1.00 125.56 ? 488 ALA A N   1 
ATOM   3619 C CA  . ALA A 1 487 ? 133.346 147.427 159.091 1.00 121.87 ? 488 ALA A CA  1 
ATOM   3620 C C   . ALA A 1 487 ? 131.990 147.376 158.397 1.00 121.33 ? 488 ALA A C   1 
ATOM   3621 O O   . ALA A 1 487 ? 131.798 146.569 157.481 1.00 125.30 ? 488 ALA A O   1 
ATOM   3622 C CB  . ALA A 1 487 ? 133.496 146.240 160.041 1.00 126.46 ? 488 ALA A CB  1 
ATOM   3623 N N   . LEU A 1 488 ? 131.038 148.209 158.824 1.00 120.27 ? 489 LEU A N   1 
ATOM   3624 C CA  . LEU A 1 488 ? 129.749 148.267 158.143 1.00 121.41 ? 489 LEU A CA  1 
ATOM   3625 C C   . LEU A 1 488 ? 129.877 148.934 156.780 1.00 117.01 ? 489 LEU A C   1 
ATOM   3626 O O   . LEU A 1 488 ? 129.209 148.536 155.819 1.00 110.70 ? 489 LEU A O   1 
ATOM   3627 C CB  . LEU A 1 488 ? 128.729 149.007 159.008 1.00 126.96 ? 489 LEU A CB  1 
ATOM   3628 C CG  . LEU A 1 488 ? 127.246 148.762 158.712 1.00 133.55 ? 489 LEU A CG  1 
ATOM   3629 C CD1 . LEU A 1 488 ? 126.950 147.276 158.555 1.00 129.00 ? 489 LEU A CD1 1 
ATOM   3630 C CD2 . LEU A 1 488 ? 126.376 149.374 159.799 1.00 128.78 ? 489 LEU A CD2 1 
ATOM   3631 N N   . SER A 1 489 ? 130.727 149.958 156.682 1.00 122.54 ? 490 SER A N   1 
ATOM   3632 C CA  . SER A 1 489 ? 130.940 150.628 155.403 1.00 124.25 ? 490 SER A CA  1 
ATOM   3633 C C   . SER A 1 489 ? 131.763 149.763 154.458 1.00 117.09 ? 490 SER A C   1 
ATOM   3634 O O   . SER A 1 489 ? 131.610 149.847 153.235 1.00 112.24 ? 490 SER A O   1 
ATOM   3635 C CB  . SER A 1 489 ? 131.624 151.977 155.627 1.00 124.06 ? 490 SER A CB  1 
ATOM   3636 O OG  . SER A 1 489 ? 130.685 152.981 155.968 1.00 127.04 ? 490 SER A OG  1 
ATOM   3637 N N   . TYR A 1 490 ? 132.815 148.891 154.880 1.00 116.20 ? 491 TYR A N   1 
ATOM   3638 C CA  . TYR A 1 490 ? 133.594 147.952 154.080 1.00 113.39 ? 491 TYR A CA  1 
ATOM   3639 C C   . TYR A 1 490 ? 132.706 146.874 153.472 1.00 117.47 ? 491 TYR A C   1 
ATOM   3640 O O   . TYR A 1 490 ? 132.857 146.515 152.299 1.00 118.58 ? 491 TYR A O   1 
ATOM   3641 C CB  . TYR A 1 490 ? 134.689 147.329 154.949 1.00 111.36 ? 491 TYR A CB  1 
ATOM   3642 C CG  . TYR A 1 490 ? 135.881 146.757 154.207 1.00 115.19 ? 491 TYR A CG  1 
ATOM   3643 C CD1 . TYR A 1 490 ? 135.720 145.989 153.062 1.00 117.51 ? 491 TYR A CD1 1 
ATOM   3644 C CD2 . TYR A 1 490 ? 137.171 146.973 154.667 1.00 123.53 ? 491 TYR A CD2 1 
ATOM   3645 C CE1 . TYR A 1 490 ? 136.803 145.462 152.396 1.00 117.23 ? 491 TYR A CE1 1 
ATOM   3646 C CE2 . TYR A 1 490 ? 138.261 146.450 154.006 1.00 120.89 ? 491 TYR A CE2 1 
ATOM   3647 C CZ  . TYR A 1 490 ? 138.071 145.695 152.872 1.00 116.43 ? 491 TYR A CZ  1 
ATOM   3648 O OH  . TYR A 1 490 ? 139.155 145.169 152.214 1.00 123.99 ? 491 TYR A OH  1 
ATOM   3649 N N   . ALA A 1 491 ? 131.729 146.447 154.214 1.00 120.41 ? 492 ALA A N   1 
ATOM   3650 C CA  . ALA A 1 491 ? 131.012 145.280 153.709 1.00 118.00 ? 492 ALA A CA  1 
ATOM   3651 C C   . ALA A 1 491 ? 130.131 145.637 152.518 1.00 112.92 ? 492 ALA A C   1 
ATOM   3652 O O   . ALA A 1 491 ? 129.935 144.816 151.615 1.00 110.56 ? 492 ALA A O   1 
ATOM   3653 C CB  . ALA A 1 491 ? 130.177 144.655 154.826 1.00 119.42 ? 492 ALA A CB  1 
ATOM   3654 N N   . ILE A 1 492 ? 129.591 146.854 152.497 1.00 117.29 ? 493 ILE A N   1 
ATOM   3655 C CA  . ILE A 1 492 ? 128.751 147.278 151.383 1.00 117.80 ? 493 ILE A CA  1 
ATOM   3656 C C   . ILE A 1 492 ? 129.579 147.875 150.246 1.00 114.94 ? 493 ILE A C   1 
ATOM   3657 O O   . ILE A 1 492 ? 129.152 147.824 149.083 1.00 118.65 ? 493 ILE A O   1 
ATOM   3658 C CB  . ILE A 1 492 ? 127.662 148.247 151.899 1.00 126.83 ? 493 ILE A CB  1 
ATOM   3659 C CG1 . ILE A 1 492 ? 126.554 148.468 150.861 1.00 127.44 ? 493 ILE A CG1 1 
ATOM   3660 C CG2 . ILE A 1 492 ? 128.257 149.575 152.369 1.00 122.14 ? 493 ILE A CG2 1 
ATOM   3661 C CD1 . ILE A 1 492 ? 125.734 147.231 150.567 1.00 125.96 ? 493 ILE A CD1 1 
ATOM   3662 N N   . SER A 1 493 ? 130.772 148.397 150.537 1.00 115.15 ? 494 SER A N   1 
ATOM   3663 C CA  . SER A 1 493 ? 131.616 148.963 149.492 1.00 114.32 ? 494 SER A CA  1 
ATOM   3664 C C   . SER A 1 493 ? 132.320 147.890 148.675 1.00 111.59 ? 494 SER A C   1 
ATOM   3665 O O   . SER A 1 493 ? 132.664 148.136 147.516 1.00 111.41 ? 494 SER A O   1 
ATOM   3666 C CB  . SER A 1 493 ? 132.652 149.904 150.104 1.00 122.49 ? 494 SER A CB  1 
ATOM   3667 O OG  . SER A 1 493 ? 132.026 151.010 150.727 1.00 123.37 ? 494 SER A OG  1 
ATOM   3668 N N   . SER A 1 494 ? 132.560 146.717 149.264 1.00 114.00 ? 495 SER A N   1 
ATOM   3669 C CA  . SER A 1 494 ? 133.305 145.665 148.571 1.00 110.90 ? 495 SER A CA  1 
ATOM   3670 C C   . SER A 1 494 ? 132.620 145.087 147.326 1.00 110.50 ? 495 SER A C   1 
ATOM   3671 O O   . SER A 1 494 ? 133.322 144.911 146.316 1.00 113.07 ? 495 SER A O   1 
ATOM   3672 C CB  . SER A 1 494 ? 133.717 144.576 149.575 1.00 114.85 ? 495 SER A CB  1 
ATOM   3673 O OG  . SER A 1 494 ? 132.636 143.867 150.147 1.00 120.87 ? 495 SER A OG  1 
ATOM   3674 N N   . PRO A 1 495 ? 131.275 144.754 147.296 1.00 111.99 ? 496 PRO A N   1 
ATOM   3675 C CA  . PRO A 1 495 ? 130.734 144.219 146.035 1.00 113.22 ? 496 PRO A CA  1 
ATOM   3676 C C   . PRO A 1 495 ? 130.606 145.276 144.953 1.00 118.47 ? 496 PRO A C   1 
ATOM   3677 O O   . PRO A 1 495 ? 130.951 145.022 143.796 1.00 122.40 ? 496 PRO A O   1 
ATOM   3678 C CB  . PRO A 1 495 ? 129.349 143.684 146.426 1.00 113.90 ? 496 PRO A CB  1 
ATOM   3679 C CG  . PRO A 1 495 ? 129.319 143.652 147.878 1.00 120.11 ? 496 PRO A CG  1 
ATOM   3680 C CD  . PRO A 1 495 ? 130.204 144.764 148.313 1.00 120.64 ? 496 PRO A CD  1 
ATOM   3681 N N   . LEU A 1 496 ? 130.106 146.458 145.331 1.00 115.84 ? 497 LEU A N   1 
ATOM   3682 C CA  . LEU A 1 496 ? 129.779 147.496 144.356 1.00 114.04 ? 497 LEU A CA  1 
ATOM   3683 C C   . LEU A 1 496 ? 131.027 148.068 143.696 1.00 112.57 ? 497 LEU A C   1 
ATOM   3684 O O   . LEU A 1 496 ? 131.023 148.350 142.493 1.00 114.41 ? 497 LEU A O   1 
ATOM   3685 C CB  . LEU A 1 496 ? 128.966 148.614 145.015 1.00 119.55 ? 497 LEU A CB  1 
ATOM   3686 C CG  . LEU A 1 496 ? 127.461 148.449 145.279 1.00 126.89 ? 497 LEU A CG  1 
ATOM   3687 C CD1 . LEU A 1 496 ? 127.128 147.481 146.414 1.00 123.10 ? 497 LEU A CD1 1 
ATOM   3688 C CD2 . LEU A 1 496 ? 126.823 149.808 145.535 1.00 126.79 ? 497 LEU A CD2 1 
ATOM   3689 N N   . PHE A 1 497 ? 132.104 148.248 144.461 1.00 115.25 ? 498 PHE A N   1 
ATOM   3690 C CA  . PHE A 1 497 ? 133.336 148.745 143.860 1.00 115.57 ? 498 PHE A CA  1 
ATOM   3691 C C   . PHE A 1 497 ? 134.087 147.634 143.144 1.00 116.77 ? 498 PHE A C   1 
ATOM   3692 O O   . PHE A 1 497 ? 134.963 147.911 142.318 1.00 117.36 ? 498 PHE A O   1 
ATOM   3693 C CB  . PHE A 1 497 ? 134.207 149.400 144.927 1.00 112.75 ? 498 PHE A CB  1 
ATOM   3694 C CG  . PHE A 1 497 ? 133.733 150.764 145.323 1.00 111.45 ? 498 PHE A CG  1 
ATOM   3695 C CD1 . PHE A 1 497 ? 133.310 151.668 144.362 1.00 103.77 ? 498 PHE A CD1 1 
ATOM   3696 C CD2 . PHE A 1 497 ? 133.666 151.127 146.656 1.00 116.74 ? 498 PHE A CD2 1 
ATOM   3697 C CE1 . PHE A 1 497 ? 132.858 152.921 144.721 1.00 105.27 ? 498 PHE A CE1 1 
ATOM   3698 C CE2 . PHE A 1 497 ? 133.214 152.378 147.023 1.00 116.95 ? 498 PHE A CE2 1 
ATOM   3699 C CZ  . PHE A 1 497 ? 132.807 153.275 146.055 1.00 114.86 ? 498 PHE A CZ  1 
ATOM   3700 N N   . GLY A 1 498 ? 133.766 146.377 143.451 1.00 113.91 ? 499 GLY A N   1 
ATOM   3701 C CA  . GLY A 1 498 ? 134.245 145.281 142.627 1.00 117.28 ? 499 GLY A CA  1 
ATOM   3702 C C   . GLY A 1 498 ? 133.347 145.033 141.431 1.00 117.54 ? 499 GLY A C   1 
ATOM   3703 O O   . GLY A 1 498 ? 133.777 144.456 140.429 1.00 116.63 ? 499 GLY A O   1 
ATOM   3704 N N   . LEU A 1 499 ? 132.084 145.457 141.524 1.00 119.61 ? 500 LEU A N   1 
ATOM   3705 C CA  . LEU A 1 499 ? 131.175 145.361 140.386 1.00 121.91 ? 500 LEU A CA  1 
ATOM   3706 C C   . LEU A 1 499 ? 131.572 146.339 139.289 1.00 118.23 ? 500 LEU A C   1 
ATOM   3707 O O   . LEU A 1 499 ? 131.536 146.006 138.100 1.00 119.88 ? 500 LEU A O   1 
ATOM   3708 C CB  . LEU A 1 499 ? 129.737 145.621 140.839 1.00 130.91 ? 500 LEU A CB  1 
ATOM   3709 C CG  . LEU A 1 499 ? 128.612 145.500 139.811 1.00 138.02 ? 500 LEU A CG  1 
ATOM   3710 C CD1 . LEU A 1 499 ? 128.515 144.078 139.288 1.00 135.47 ? 500 LEU A CD1 1 
ATOM   3711 C CD2 . LEU A 1 499 ? 127.288 145.945 140.413 1.00 131.43 ? 500 LEU A CD2 1 
ATOM   3712 N N   . LEU A 1 500 ? 131.956 147.558 139.674 1.00 119.32 ? 501 LEU A N   1 
ATOM   3713 C CA  . LEU A 1 500 ? 132.333 148.569 138.694 1.00 116.85 ? 501 LEU A CA  1 
ATOM   3714 C C   . LEU A 1 500 ? 133.787 148.448 138.261 1.00 118.70 ? 501 LEU A C   1 
ATOM   3715 O O   . LEU A 1 500 ? 134.186 149.101 137.292 1.00 124.95 ? 501 LEU A O   1 
ATOM   3716 C CB  . LEU A 1 500 ? 132.078 149.976 139.243 1.00 116.76 ? 501 LEU A CB  1 
ATOM   3717 C CG  . LEU A 1 500 ? 130.694 150.636 139.135 1.00 121.53 ? 501 LEU A CG  1 
ATOM   3718 C CD1 . LEU A 1 500 ? 130.320 150.844 137.671 1.00 111.61 ? 501 LEU A CD1 1 
ATOM   3719 C CD2 . LEU A 1 500 ? 129.585 149.896 139.880 1.00 125.09 ? 501 LEU A CD2 1 
ATOM   3720 N N   . SER A 1 501 ? 134.587 147.637 138.955 1.00 117.20 ? 502 SER A N   1 
ATOM   3721 C CA  . SER A 1 501 ? 135.983 147.473 138.562 1.00 123.76 ? 502 SER A CA  1 
ATOM   3722 C C   . SER A 1 501 ? 136.116 146.568 137.346 1.00 125.73 ? 502 SER A C   1 
ATOM   3723 O O   . SER A 1 501 ? 136.999 146.773 136.506 1.00 128.44 ? 502 SER A O   1 
ATOM   3724 C CB  . SER A 1 501 ? 136.796 146.916 139.729 1.00 125.60 ? 502 SER A CB  1 
ATOM   3725 O OG  . SER A 1 501 ? 138.148 146.716 139.358 1.00 133.58 ? 502 SER A OG  1 
ATOM   3726 N N   . ASP A 1 502 ? 135.252 145.559 137.238 1.00 123.29 ? 503 ASP A N   1 
ATOM   3727 C CA  . ASP A 1 502 ? 135.372 144.576 136.168 1.00 126.13 ? 503 ASP A CA  1 
ATOM   3728 C C   . ASP A 1 502 ? 134.881 145.115 134.828 1.00 124.50 ? 503 ASP A C   1 
ATOM   3729 O O   . ASP A 1 502 ? 135.486 144.821 133.792 1.00 126.77 ? 503 ASP A O   1 
ATOM   3730 C CB  . ASP A 1 502 ? 134.591 143.315 136.545 1.00 131.95 ? 503 ASP A CB  1 
ATOM   3731 C CG  . ASP A 1 502 ? 134.749 142.192 135.533 1.00 133.16 ? 503 ASP A CG  1 
ATOM   3732 O OD1 . ASP A 1 502 ? 135.774 142.149 134.819 1.00 127.46 ? 503 ASP A OD1 1 
ATOM   3733 O OD2 . ASP A 1 502 ? 133.831 141.350 135.447 1.00 136.25 ? 503 ASP A OD2 1 
ATOM   3734 N N   . LYS A 1 503 ? 133.804 145.903 134.827 1.00 122.40 ? 504 LYS A N   1 
ATOM   3735 C CA  . LYS A 1 503 ? 133.165 146.281 133.569 1.00 127.34 ? 504 LYS A CA  1 
ATOM   3736 C C   . LYS A 1 503 ? 133.950 147.354 132.824 1.00 124.72 ? 504 LYS A C   1 
ATOM   3737 O O   . LYS A 1 503 ? 133.917 147.405 131.589 1.00 126.28 ? 504 LYS A O   1 
ATOM   3738 C CB  . LYS A 1 503 ? 131.722 146.736 133.808 1.00 130.76 ? 504 LYS A CB  1 
ATOM   3739 C CG  . LYS A 1 503 ? 130.679 145.607 133.876 1.00 136.14 ? 504 LYS A CG  1 
ATOM   3740 C CD  . LYS A 1 503 ? 130.725 144.781 135.152 1.00 139.62 ? 504 LYS A CD  1 
ATOM   3741 C CE  . LYS A 1 503 ? 129.613 143.747 135.179 1.00 145.36 ? 504 LYS A CE  1 
ATOM   3742 N NZ  . LYS A 1 503 ? 129.726 142.846 136.356 1.00 132.44 ? 504 LYS A NZ  1 
ATOM   3743 N N   . ARG A 1 504 ? 134.662 148.222 133.544 1.00 122.94 ? 505 ARG A N   1 
ATOM   3744 C CA  . ARG A 1 504 ? 135.466 149.270 132.914 1.00 128.72 ? 505 ARG A CA  1 
ATOM   3745 C C   . ARG A 1 504 ? 136.920 149.155 133.357 1.00 122.79 ? 505 ARG A C   1 
ATOM   3746 O O   . ARG A 1 504 ? 137.314 149.723 134.388 1.00 122.22 ? 505 ARG A O   1 
ATOM   3747 C CB  . ARG A 1 504 ? 134.890 150.653 133.211 1.00 131.55 ? 505 ARG A CB  1 
ATOM   3748 C CG  . ARG A 1 504 ? 133.542 150.884 132.531 1.00 131.25 ? 505 ARG A CG  1 
ATOM   3749 C CD  . ARG A 1 504 ? 132.981 152.263 132.814 1.00 132.93 ? 505 ARG A CD  1 
ATOM   3750 N NE  . ARG A 1 504 ? 131.692 152.469 132.167 1.00 136.39 ? 505 ARG A NE  1 
ATOM   3751 C CZ  . ARG A 1 504 ? 130.962 153.571 132.282 1.00 139.69 ? 505 ARG A CZ  1 
ATOM   3752 N NH1 . ARG A 1 504 ? 131.374 154.600 133.003 1.00 128.08 ? 505 ARG A NH1 1 
ATOM   3753 N NH2 . ARG A 1 504 ? 129.793 153.643 131.652 1.00 138.22 ? 505 ARG A NH2 1 
ATOM   3754 N N   . PRO A 1 505 ? 137.738 148.400 132.624 1.00 120.19 ? 506 PRO A N   1 
ATOM   3755 C CA  . PRO A 1 505 ? 139.181 148.295 132.936 1.00 124.33 ? 506 PRO A CA  1 
ATOM   3756 C C   . PRO A 1 505 ? 139.971 149.600 132.843 1.00 122.66 ? 506 PRO A C   1 
ATOM   3757 O O   . PRO A 1 505 ? 140.936 149.741 133.608 1.00 125.20 ? 506 PRO A O   1 
ATOM   3758 C CB  . PRO A 1 505 ? 139.685 147.261 131.914 1.00 130.40 ? 506 PRO A CB  1 
ATOM   3759 C CG  . PRO A 1 505 ? 138.495 146.436 131.602 1.00 121.20 ? 506 PRO A CG  1 
ATOM   3760 C CD  . PRO A 1 505 ? 137.312 147.361 131.667 1.00 118.71 ? 506 PRO A CD  1 
ATOM   3761 N N   . PRO A 1 506 ? 139.688 150.562 131.931 1.00 120.27 ? 507 PRO A N   1 
ATOM   3762 C CA  . PRO A 1 506 ? 140.478 151.813 131.995 1.00 121.51 ? 507 PRO A CA  1 
ATOM   3763 C C   . PRO A 1 506 ? 140.216 152.684 133.217 1.00 125.15 ? 507 PRO A C   1 
ATOM   3764 O O   . PRO A 1 506 ? 141.055 153.539 133.523 1.00 120.87 ? 507 PRO A O   1 
ATOM   3765 C CB  . PRO A 1 506 ? 140.094 152.554 130.707 1.00 121.53 ? 507 PRO A CB  1 
ATOM   3766 C CG  . PRO A 1 506 ? 139.666 151.527 129.798 1.00 122.52 ? 507 PRO A CG  1 
ATOM   3767 C CD  . PRO A 1 506 ? 138.966 150.522 130.636 1.00 125.10 ? 507 PRO A CD  1 
ATOM   3768 N N   . LEU A 1 507 ? 139.100 152.509 133.923 1.00 126.92 ? 508 LEU A N   1 
ATOM   3769 C CA  . LEU A 1 507 ? 138.807 153.373 135.060 1.00 118.88 ? 508 LEU A CA  1 
ATOM   3770 C C   . LEU A 1 507 ? 139.188 152.773 136.406 1.00 114.14 ? 508 LEU A C   1 
ATOM   3771 O O   . LEU A 1 507 ? 138.901 153.390 137.437 1.00 116.82 ? 508 LEU A O   1 
ATOM   3772 C CB  . LEU A 1 507 ? 137.322 153.749 135.080 1.00 125.09 ? 508 LEU A CB  1 
ATOM   3773 C CG  . LEU A 1 507 ? 136.853 154.637 133.927 1.00 131.48 ? 508 LEU A CG  1 
ATOM   3774 C CD1 . LEU A 1 507 ? 135.354 154.853 133.993 1.00 130.70 ? 508 LEU A CD1 1 
ATOM   3775 C CD2 . LEU A 1 507 ? 137.590 155.969 133.942 1.00 130.54 ? 508 LEU A CD2 1 
ATOM   3776 N N   . ARG A 1 508 ? 139.821 151.597 136.433 1.00 113.41 ? 509 ARG A N   1 
ATOM   3777 C CA  . ARG A 1 508 ? 140.300 151.063 137.704 1.00 114.88 ? 509 ARG A CA  1 
ATOM   3778 C C   . ARG A 1 508 ? 141.536 151.801 138.199 1.00 116.46 ? 509 ARG A C   1 
ATOM   3779 O O   . ARG A 1 508 ? 141.855 151.726 139.390 1.00 112.51 ? 509 ARG A O   1 
ATOM   3780 C CB  . ARG A 1 508 ? 140.605 149.567 137.586 1.00 118.21 ? 509 ARG A CB  1 
ATOM   3781 C CG  . ARG A 1 508 ? 141.798 149.245 136.707 1.00 121.59 ? 509 ARG A CG  1 
ATOM   3782 C CD  . ARG A 1 508 ? 141.994 147.755 136.516 1.00 118.14 ? 509 ARG A CD  1 
ATOM   3783 N NE  . ARG A 1 508 ? 140.918 147.164 135.731 1.00 121.77 ? 509 ARG A NE  1 
ATOM   3784 C CZ  . ARG A 1 508 ? 140.781 145.865 135.513 1.00 125.51 ? 509 ARG A CZ  1 
ATOM   3785 N NH1 . ARG A 1 508 ? 141.677 144.995 135.944 1.00 126.57 ? 509 ARG A NH1 1 
ATOM   3786 N NH2 . ARG A 1 508 ? 139.726 145.429 134.831 1.00 126.77 ? 509 ARG A NH2 1 
ATOM   3787 N N   . LYS A 1 509 ? 142.240 152.508 137.312 1.00 120.03 ? 510 LYS A N   1 
ATOM   3788 C CA  . LYS A 1 509 ? 143.405 153.283 137.719 1.00 118.37 ? 510 LYS A CA  1 
ATOM   3789 C C   . LYS A 1 509 ? 143.003 154.633 138.299 1.00 118.66 ? 510 LYS A C   1 
ATOM   3790 O O   . LYS A 1 509 ? 143.735 155.202 139.115 1.00 121.33 ? 510 LYS A O   1 
ATOM   3791 C CB  . LYS A 1 509 ? 144.360 153.450 136.535 1.00 124.52 ? 510 LYS A CB  1 
ATOM   3792 C CG  . LYS A 1 509 ? 143.814 154.259 135.368 1.00 129.14 ? 510 LYS A CG  1 
ATOM   3793 C CD  . LYS A 1 509 ? 144.812 154.319 134.226 1.00 136.16 ? 510 LYS A CD  1 
ATOM   3794 C CE  . LYS A 1 509 ? 144.273 155.137 133.065 1.00 140.66 ? 510 LYS A CE  1 
ATOM   3795 N NZ  . LYS A 1 509 ? 145.238 155.195 131.933 1.00 146.35 ? 510 LYS A NZ  1 
ATOM   3796 N N   . TRP A 1 510 ? 141.849 155.163 137.892 1.00 120.41 ? 511 TRP A N   1 
ATOM   3797 C CA  . TRP A 1 510 ? 141.336 156.388 138.489 1.00 123.35 ? 511 TRP A CA  1 
ATOM   3798 C C   . TRP A 1 510 ? 140.541 156.101 139.752 1.00 120.15 ? 511 TRP A C   1 
ATOM   3799 O O   . TRP A 1 510 ? 140.425 156.971 140.622 1.00 124.14 ? 511 TRP A O   1 
ATOM   3800 C CB  . TRP A 1 510 ? 140.465 157.137 137.481 1.00 131.26 ? 511 TRP A CB  1 
ATOM   3801 C CG  . TRP A 1 510 ? 141.231 157.684 136.322 1.00 137.79 ? 511 TRP A CG  1 
ATOM   3802 C CD1 . TRP A 1 510 ? 141.388 157.106 135.098 1.00 139.10 ? 511 TRP A CD1 1 
ATOM   3803 C CD2 . TRP A 1 510 ? 141.936 158.928 136.272 1.00 137.81 ? 511 TRP A CD2 1 
ATOM   3804 N NE1 . TRP A 1 510 ? 142.155 157.908 134.290 1.00 139.63 ? 511 TRP A NE1 1 
ATOM   3805 C CE2 . TRP A 1 510 ? 142.503 159.035 134.987 1.00 140.38 ? 511 TRP A CE2 1 
ATOM   3806 C CE3 . TRP A 1 510 ? 142.145 159.961 137.190 1.00 140.65 ? 511 TRP A CE3 1 
ATOM   3807 C CZ2 . TRP A 1 510 ? 143.265 160.133 134.597 1.00 146.89 ? 511 TRP A CZ2 1 
ATOM   3808 C CZ3 . TRP A 1 510 ? 142.902 161.052 136.801 1.00 145.59 ? 511 TRP A CZ3 1 
ATOM   3809 C CH2 . TRP A 1 510 ? 143.453 161.129 135.516 1.00 146.58 ? 511 TRP A CH2 1 
ATOM   3810 N N   . LEU A 1 511 ? 139.989 154.893 139.861 1.00 114.96 ? 512 LEU A N   1 
ATOM   3811 C CA  . LEU A 1 511 ? 139.179 154.539 141.020 1.00 113.81 ? 512 LEU A CA  1 
ATOM   3812 C C   . LEU A 1 511 ? 140.053 154.298 142.244 1.00 111.89 ? 512 LEU A C   1 
ATOM   3813 O O   . LEU A 1 511 ? 139.628 154.537 143.380 1.00 118.28 ? 512 LEU A O   1 
ATOM   3814 C CB  . LEU A 1 511 ? 138.348 153.297 140.700 1.00 115.72 ? 512 LEU A CB  1 
ATOM   3815 C CG  . LEU A 1 511 ? 137.328 152.785 141.713 1.00 116.81 ? 512 LEU A CG  1 
ATOM   3816 C CD1 . LEU A 1 511 ? 136.236 153.825 141.900 1.00 114.29 ? 512 LEU A CD1 1 
ATOM   3817 C CD2 . LEU A 1 511 ? 136.741 151.458 141.265 1.00 115.93 ? 512 LEU A CD2 1 
ATOM   3818 N N   . LEU A 1 512 ? 141.286 153.836 142.030 1.00 109.54 ? 513 LEU A N   1 
ATOM   3819 C CA  . LEU A 1 512 ? 142.118 153.399 143.145 1.00 115.11 ? 513 LEU A CA  1 
ATOM   3820 C C   . LEU A 1 512 ? 142.983 154.535 143.677 1.00 117.73 ? 513 LEU A C   1 
ATOM   3821 O O   . LEU A 1 512 ? 143.215 154.625 144.889 1.00 116.92 ? 513 LEU A O   1 
ATOM   3822 C CB  . LEU A 1 512 ? 142.982 152.216 142.704 1.00 119.90 ? 513 LEU A CB  1 
ATOM   3823 C CG  . LEU A 1 512 ? 143.885 151.520 143.723 1.00 119.94 ? 513 LEU A CG  1 
ATOM   3824 C CD1 . LEU A 1 512 ? 143.783 150.024 143.542 1.00 119.75 ? 513 LEU A CD1 1 
ATOM   3825 C CD2 . LEU A 1 512 ? 145.320 151.953 143.582 1.00 108.11 ? 513 LEU A CD2 1 
ATOM   3826 N N   . VAL A 1 513 ? 143.489 155.393 142.786 1.00 116.78 ? 514 VAL A N   1 
ATOM   3827 C CA  . VAL A 1 513 ? 144.317 156.520 143.209 1.00 110.32 ? 514 VAL A CA  1 
ATOM   3828 C C   . VAL A 1 513 ? 143.478 157.544 143.965 1.00 110.78 ? 514 VAL A C   1 
ATOM   3829 O O   . VAL A 1 513 ? 143.917 158.103 144.979 1.00 106.59 ? 514 VAL A O   1 
ATOM   3830 C CB  . VAL A 1 513 ? 145.028 157.135 141.987 1.00 114.23 ? 514 VAL A CB  1 
ATOM   3831 C CG1 . VAL A 1 513 ? 145.805 158.386 142.367 1.00 121.03 ? 514 VAL A CG1 1 
ATOM   3832 C CG2 . VAL A 1 513 ? 145.967 156.119 141.366 1.00 107.18 ? 514 VAL A CG2 1 
ATOM   3833 N N   . PHE A 1 514 ? 142.243 157.772 143.513 1.00 113.43 ? 515 PHE A N   1 
ATOM   3834 C CA  . PHE A 1 514 ? 141.334 158.645 144.249 1.00 114.10 ? 515 PHE A CA  1 
ATOM   3835 C C   . PHE A 1 514 ? 140.867 158.009 145.553 1.00 118.14 ? 515 PHE A C   1 
ATOM   3836 O O   . PHE A 1 514 ? 140.428 158.722 146.459 1.00 120.06 ? 515 PHE A O   1 
ATOM   3837 C CB  . PHE A 1 514 ? 140.129 159.016 143.382 1.00 119.83 ? 515 PHE A CB  1 
ATOM   3838 C CG  . PHE A 1 514 ? 140.451 159.940 142.235 1.00 130.28 ? 515 PHE A CG  1 
ATOM   3839 C CD1 . PHE A 1 514 ? 141.646 160.649 142.196 1.00 130.43 ? 515 PHE A CD1 1 
ATOM   3840 C CD2 . PHE A 1 514 ? 139.548 160.103 141.194 1.00 137.22 ? 515 PHE A CD2 1 
ATOM   3841 C CE1 . PHE A 1 514 ? 141.935 161.496 141.141 1.00 135.03 ? 515 PHE A CE1 1 
ATOM   3842 C CE2 . PHE A 1 514 ? 139.831 160.950 140.135 1.00 139.88 ? 515 PHE A CE2 1 
ATOM   3843 C CZ  . PHE A 1 514 ? 141.025 161.648 140.110 1.00 139.20 ? 515 PHE A CZ  1 
ATOM   3844 N N   . GLY A 1 515 ? 140.939 156.680 145.661 1.00 113.76 ? 516 GLY A N   1 
ATOM   3845 C CA  . GLY A 1 515 ? 140.633 156.030 146.926 1.00 112.77 ? 516 GLY A CA  1 
ATOM   3846 C C   . GLY A 1 515 ? 141.663 156.319 148.000 1.00 112.40 ? 516 GLY A C   1 
ATOM   3847 O O   . GLY A 1 515 ? 141.324 156.486 149.173 1.00 112.40 ? 516 GLY A O   1 
ATOM   3848 N N   . ASN A 1 516 ? 142.937 156.372 147.613 1.00 113.77 ? 517 ASN A N   1 
ATOM   3849 C CA  . ASN A 1 516 ? 143.994 156.664 148.571 1.00 110.05 ? 517 ASN A CA  1 
ATOM   3850 C C   . ASN A 1 516 ? 143.998 158.148 148.928 1.00 114.37 ? 517 ASN A C   1 
ATOM   3851 O O   . ASN A 1 516 ? 144.333 158.516 150.060 1.00 113.61 ? 517 ASN A O   1 
ATOM   3852 C CB  . ASN A 1 516 ? 145.334 156.222 147.972 1.00 108.48 ? 517 ASN A CB  1 
ATOM   3853 C CG  . ASN A 1 516 ? 146.482 156.215 148.973 1.00 115.95 ? 517 ASN A CG  1 
ATOM   3854 O OD1 . ASN A 1 516 ? 146.331 156.547 150.146 1.00 119.07 ? 517 ASN A OD1 1 
ATOM   3855 N ND2 . ASN A 1 516 ? 147.651 155.816 148.496 1.00 116.81 ? 517 ASN A ND2 1 
ATOM   3856 N N   . LEU A 1 517 ? 143.601 159.005 147.982 1.00 117.97 ? 518 LEU A N   1 
ATOM   3857 C CA  . LEU A 1 517 ? 143.614 160.447 148.211 1.00 110.91 ? 518 LEU A CA  1 
ATOM   3858 C C   . LEU A 1 517 ? 142.550 160.863 149.221 1.00 114.81 ? 518 LEU A C   1 
ATOM   3859 O O   . LEU A 1 517 ? 142.765 161.788 150.013 1.00 118.24 ? 518 LEU A O   1 
ATOM   3860 C CB  . LEU A 1 517 ? 143.417 161.179 146.884 1.00 114.88 ? 518 LEU A CB  1 
ATOM   3861 C CG  . LEU A 1 517 ? 143.461 162.707 146.892 1.00 129.44 ? 518 LEU A CG  1 
ATOM   3862 C CD1 . LEU A 1 517 ? 144.828 163.199 147.336 1.00 129.75 ? 518 LEU A CD1 1 
ATOM   3863 C CD2 . LEU A 1 517 ? 143.102 163.261 145.522 1.00 123.42 ? 518 LEU A CD2 1 
ATOM   3864 N N   . ILE A 1 518 ? 141.393 160.195 149.203 1.00 116.08 ? 519 ILE A N   1 
ATOM   3865 C CA  . ILE A 1 518 ? 140.370 160.443 150.216 1.00 114.47 ? 519 ILE A CA  1 
ATOM   3866 C C   . ILE A 1 518 ? 140.839 159.937 151.577 1.00 116.05 ? 519 ILE A C   1 
ATOM   3867 O O   . ILE A 1 518 ? 140.589 160.572 152.610 1.00 120.15 ? 519 ILE A O   1 
ATOM   3868 C CB  . ILE A 1 518 ? 139.034 159.807 149.781 1.00 116.40 ? 519 ILE A CB  1 
ATOM   3869 C CG1 . ILE A 1 518 ? 138.541 160.449 148.487 1.00 121.95 ? 519 ILE A CG1 1 
ATOM   3870 C CG2 . ILE A 1 518 ? 137.954 159.988 150.834 1.00 123.55 ? 519 ILE A CG2 1 
ATOM   3871 C CD1 . ILE A 1 518 ? 137.381 159.718 147.849 1.00 125.36 ? 519 ILE A CD1 1 
ATOM   3872 N N   . THR A 1 519 ? 141.556 158.806 151.590 1.00 118.57 ? 520 THR A N   1 
ATOM   3873 C CA  . THR A 1 519 ? 142.066 158.230 152.834 1.00 120.80 ? 520 THR A CA  1 
ATOM   3874 C C   . THR A 1 519 ? 143.092 159.149 153.492 1.00 121.50 ? 520 THR A C   1 
ATOM   3875 O O   . THR A 1 519 ? 143.155 159.246 154.724 1.00 127.23 ? 520 THR A O   1 
ATOM   3876 C CB  . THR A 1 519 ? 142.667 156.850 152.547 1.00 124.20 ? 520 THR A CB  1 
ATOM   3877 O OG1 . THR A 1 519 ? 141.701 156.045 151.859 1.00 126.62 ? 520 THR A OG1 1 
ATOM   3878 C CG2 . THR A 1 519 ? 143.058 156.132 153.835 1.00 124.55 ? 520 THR A CG2 1 
ATOM   3879 N N   . ALA A 1 520 ? 143.887 159.852 152.683 1.00 122.18 ? 521 ALA A N   1 
ATOM   3880 C CA  . ALA A 1 520 ? 144.775 160.880 153.217 1.00 123.90 ? 521 ALA A CA  1 
ATOM   3881 C C   . ALA A 1 520 ? 143.981 162.057 153.772 1.00 121.93 ? 521 ALA A C   1 
ATOM   3882 O O   . ALA A 1 520 ? 144.357 162.652 154.787 1.00 125.05 ? 521 ALA A O   1 
ATOM   3883 C CB  . ALA A 1 520 ? 145.744 161.349 152.133 1.00 126.29 ? 521 ALA A CB  1 
ATOM   3884 N N   . GLY A 1 521 ? 142.877 162.409 153.112 1.00 123.32 ? 522 GLY A N   1 
ATOM   3885 C CA  . GLY A 1 521 ? 142.075 163.528 153.579 1.00 127.08 ? 522 GLY A CA  1 
ATOM   3886 C C   . GLY A 1 521 ? 141.240 163.195 154.802 1.00 130.91 ? 522 GLY A C   1 
ATOM   3887 O O   . GLY A 1 521 ? 140.975 164.067 155.635 1.00 135.72 ? 522 GLY A O   1 
ATOM   3888 N N   . CYS A 1 522 ? 140.801 161.938 154.920 1.00 127.71 ? 523 CYS A N   1 
ATOM   3889 C CA  . CYS A 1 522 ? 139.972 161.543 156.057 1.00 125.20 ? 523 CYS A CA  1 
ATOM   3890 C C   . CYS A 1 522 ? 140.773 161.511 157.351 1.00 126.17 ? 523 CYS A C   1 
ATOM   3891 O O   . CYS A 1 522 ? 140.299 161.979 158.393 1.00 132.04 ? 523 CYS A O   1 
ATOM   3892 C CB  . CYS A 1 522 ? 139.330 160.180 155.799 1.00 128.74 ? 523 CYS A CB  1 
ATOM   3893 S SG  . CYS A 1 522 ? 138.025 160.182 154.557 1.00 126.74 ? 523 CYS A SG  1 
ATOM   3894 N N   . TYR A 1 523 ? 142.031 160.905 157.102 1.00 121.27 ? 524 TYR A N   1 
ATOM   3895 C CA  . TYR A 1 523 ? 142.929 160.818 158.244 1.00 124.67 ? 524 TYR A CA  1 
ATOM   3896 C C   . TYR A 1 523 ? 143.526 162.173 158.591 1.00 131.32 ? 524 TYR A C   1 
ATOM   3897 O O   . TYR A 1 523 ? 143.939 162.390 159.735 1.00 138.57 ? 524 TYR A O   1 
ATOM   3898 C CB  . TYR A 1 523 ? 144.031 159.804 157.957 1.00 124.76 ? 524 TYR A CB  1 
ATOM   3899 C CG  . TYR A 1 523 ? 143.700 158.422 158.457 1.00 128.65 ? 524 TYR A CG  1 
ATOM   3900 C CD1 . TYR A 1 523 ? 142.908 158.242 159.578 1.00 133.44 ? 524 TYR A CD1 1 
ATOM   3901 C CD2 . TYR A 1 523 ? 144.151 157.299 157.790 1.00 127.39 ? 524 TYR A CD2 1 
ATOM   3902 C CE1 . TYR A 1 523 ? 142.593 156.981 160.034 1.00 132.70 ? 524 TYR A CE1 1 
ATOM   3903 C CE2 . TYR A 1 523 ? 143.837 156.040 158.236 1.00 130.81 ? 524 TYR A CE2 1 
ATOM   3904 C CZ  . TYR A 1 523 ? 143.063 155.882 159.356 1.00 132.69 ? 524 TYR A CZ  1 
ATOM   3905 O OH  . TYR A 1 523 ? 142.759 154.615 159.791 1.00 133.71 ? 524 TYR A OH  1 
ATOM   3906 N N   . MET A 1 524 ? 143.585 163.105 157.835 1.00 132.84 ? 525 MET A N   1 
ATOM   3907 C CA  . MET A 1 524 ? 144.036 164.459 158.133 1.00 135.70 ? 525 MET A CA  1 
ATOM   3908 C C   . MET A 1 524 ? 143.060 165.146 159.079 1.00 135.68 ? 525 MET A C   1 
ATOM   3909 O O   . MET A 1 524 ? 143.460 165.924 159.953 1.00 134.90 ? 525 MET A O   1 
ATOM   3910 C CB  . MET A 1 524 ? 144.188 165.253 156.835 1.00 135.70 ? 525 MET A CB  1 
ATOM   3911 C CG  . MET A 1 524 ? 144.809 166.631 156.988 1.00 143.02 ? 525 MET A CG  1 
ATOM   3912 S SD  . MET A 1 524 ? 146.529 166.562 157.520 1.00 154.49 ? 525 MET A SD  1 
ATOM   3913 C CE  . MET A 1 524 ? 146.716 168.181 158.257 1.00 151.35 ? 525 MET A CE  1 
ATOM   3914 N N   . LEU A 1 525 ? 141.769 164.861 158.918 1.00 138.00 ? 526 LEU A N   1 
ATOM   3915 C CA  . LEU A 1 525 ? 140.711 165.437 159.735 1.00 142.45 ? 526 LEU A CA  1 
ATOM   3916 C C   . LEU A 1 525 ? 140.223 164.507 160.839 1.00 141.01 ? 526 LEU A C   1 
ATOM   3917 O O   . LEU A 1 525 ? 139.289 164.874 161.559 1.00 143.05 ? 526 LEU A O   1 
ATOM   3918 C CB  . LEU A 1 525 ? 139.527 165.838 158.849 1.00 149.33 ? 526 LEU A CB  1 
ATOM   3919 C CG  . LEU A 1 525 ? 139.761 166.966 157.843 1.00 157.09 ? 526 LEU A CG  1 
ATOM   3920 C CD1 . LEU A 1 525 ? 138.547 167.146 156.945 1.00 153.11 ? 526 LEU A CD1 1 
ATOM   3921 C CD2 . LEU A 1 525 ? 140.092 168.263 158.563 1.00 160.23 ? 526 LEU A CD2 1 
ATOM   3922 N N   . LEU A 1 526 ? 140.800 163.308 160.969 1.00 138.75 ? 527 LEU A N   1 
ATOM   3923 C CA  . LEU A 1 526 ? 140.424 162.374 162.027 1.00 143.38 ? 527 LEU A CA  1 
ATOM   3924 C C   . LEU A 1 526 ? 140.770 162.939 163.396 1.00 147.03 ? 527 LEU A C   1 
ATOM   3925 O O   . LEU A 1 526 ? 139.881 163.221 164.205 1.00 150.83 ? 527 LEU A O   1 
ATOM   3926 C CB  . LEU A 1 526 ? 141.122 161.027 161.834 1.00 143.75 ? 527 LEU A CB  1 
ATOM   3927 C CG  . LEU A 1 526 ? 140.769 159.937 162.847 1.00 148.67 ? 527 LEU A CG  1 
ATOM   3928 C CD1 . LEU A 1 526 ? 139.297 159.571 162.755 1.00 142.97 ? 527 LEU A CD1 1 
ATOM   3929 C CD2 . LEU A 1 526 ? 141.649 158.711 162.661 1.00 146.70 ? 527 LEU A CD2 1 
ATOM   3930 N N   . GLY A 1 527 ? 142.061 163.102 163.661 1.00 149.76 ? 528 GLY A N   1 
ATOM   3931 C CA  . GLY A 1 527 ? 142.518 163.895 164.772 1.00 155.46 ? 528 GLY A CA  1 
ATOM   3932 C C   . GLY A 1 527 ? 142.973 165.236 164.244 1.00 159.41 ? 528 GLY A C   1 
ATOM   3933 O O   . GLY A 1 527 ? 144.051 165.356 163.652 1.00 162.88 ? 528 GLY A O   1 
ATOM   3934 N N   . PRO A 1 528 ? 142.145 166.266 164.421 1.00 156.71 ? 529 PRO A N   1 
ATOM   3935 C CA  . PRO A 1 528 ? 142.393 167.539 163.733 1.00 163.02 ? 529 PRO A CA  1 
ATOM   3936 C C   . PRO A 1 528 ? 143.586 168.286 164.311 1.00 164.22 ? 529 PRO A C   1 
ATOM   3937 O O   . PRO A 1 528 ? 143.788 168.334 165.527 1.00 161.53 ? 529 PRO A O   1 
ATOM   3938 C CB  . PRO A 1 528 ? 141.087 168.314 163.940 1.00 160.84 ? 529 PRO A CB  1 
ATOM   3939 C CG  . PRO A 1 528 ? 140.471 167.702 165.132 1.00 160.62 ? 529 PRO A CG  1 
ATOM   3940 C CD  . PRO A 1 528 ? 140.844 166.259 165.109 1.00 153.07 ? 529 PRO A CD  1 
ATOM   3941 N N   . VAL A 1 529 ? 144.383 168.849 163.414 1.00 164.23 ? 530 VAL A N   1 
ATOM   3942 C CA  . VAL A 1 529 ? 145.524 169.694 163.783 1.00 168.22 ? 530 VAL A CA  1 
ATOM   3943 C C   . VAL A 1 529 ? 144.995 170.981 164.408 1.00 178.63 ? 530 VAL A C   1 
ATOM   3944 O O   . VAL A 1 529 ? 143.932 171.470 163.984 1.00 175.94 ? 530 VAL A O   1 
ATOM   3945 C CB  . VAL A 1 529 ? 146.375 169.972 162.535 1.00 165.62 ? 530 VAL A CB  1 
ATOM   3946 C CG1 . VAL A 1 529 ? 147.531 170.924 162.799 1.00 170.43 ? 530 VAL A CG1 1 
ATOM   3947 C CG2 . VAL A 1 529 ? 146.893 168.666 161.969 1.00 162.93 ? 530 VAL A CG2 1 
ATOM   3948 N N   . PRO A 1 530 ? 145.655 171.543 165.452 1.00 183.51 ? 531 PRO A N   1 
ATOM   3949 C CA  . PRO A 1 530 ? 145.199 172.823 166.026 1.00 181.28 ? 531 PRO A CA  1 
ATOM   3950 C C   . PRO A 1 530 ? 145.209 174.004 165.060 1.00 180.42 ? 531 PRO A C   1 
ATOM   3951 O O   . PRO A 1 530 ? 144.501 174.990 165.290 1.00 180.38 ? 531 PRO A O   1 
ATOM   3952 C CB  . PRO A 1 530 ? 146.183 173.051 167.180 1.00 178.86 ? 531 PRO A CB  1 
ATOM   3953 C CG  . PRO A 1 530 ? 146.589 171.683 167.592 1.00 175.64 ? 531 PRO A CG  1 
ATOM   3954 C CD  . PRO A 1 530 ? 146.620 170.859 166.335 1.00 173.74 ? 531 PRO A CD  1 
ATOM   3955 N N   . ILE A 1 531 ? 146.006 173.926 163.989 1.00 180.48 ? 532 ILE A N   1 
ATOM   3956 C CA  . ILE A 1 531 ? 145.940 174.934 162.932 1.00 177.61 ? 532 ILE A CA  1 
ATOM   3957 C C   . ILE A 1 531 ? 144.620 174.838 162.175 1.00 177.12 ? 532 ILE A C   1 
ATOM   3958 O O   . ILE A 1 531 ? 144.103 175.847 161.681 1.00 180.42 ? 532 ILE A O   1 
ATOM   3959 C CB  . ILE A 1 531 ? 147.152 174.804 161.983 1.00 173.70 ? 532 ILE A CB  1 
ATOM   3960 C CG1 . ILE A 1 531 ? 148.433 174.510 162.770 1.00 177.18 ? 532 ILE A CG1 1 
ATOM   3961 C CG2 . ILE A 1 531 ? 147.332 176.066 161.148 1.00 168.18 ? 532 ILE A CG2 1 
ATOM   3962 C CD1 . ILE A 1 531 ? 148.898 175.652 163.662 1.00 175.20 ? 532 ILE A CD1 1 
ATOM   3963 N N   . LEU A 1 532 ? 144.047 173.636 162.078 1.00 173.17 ? 533 LEU A N   1 
ATOM   3964 C CA  . LEU A 1 532 ? 142.784 173.460 161.371 1.00 179.56 ? 533 LEU A CA  1 
ATOM   3965 C C   . LEU A 1 532 ? 141.588 174.015 162.139 1.00 182.86 ? 533 LEU A C   1 
ATOM   3966 O O   . LEU A 1 532 ? 140.585 174.366 161.504 1.00 184.59 ? 533 LEU A O   1 
ATOM   3967 C CB  . LEU A 1 532 ? 142.558 171.978 161.062 1.00 179.74 ? 533 LEU A CB  1 
ATOM   3968 C CG  . LEU A 1 532 ? 143.619 171.313 160.183 1.00 177.47 ? 533 LEU A CG  1 
ATOM   3969 C CD1 . LEU A 1 532 ? 143.255 169.865 159.903 1.00 172.49 ? 533 LEU A CD1 1 
ATOM   3970 C CD2 . LEU A 1 532 ? 143.804 172.082 158.882 1.00 177.45 ? 533 LEU A CD2 1 
ATOM   3971 N N   . HIS A 1 533 ? 141.687 174.098 163.473 1.00 179.74 ? 534 HIS A N   1 
ATOM   3972 C CA  . HIS A 1 533 ? 140.650 174.635 164.369 1.00 174.70 ? 534 HIS A CA  1 
ATOM   3973 C C   . HIS A 1 533 ? 139.316 173.905 164.215 1.00 176.72 ? 534 HIS A C   1 
ATOM   3974 O O   . HIS A 1 533 ? 138.259 174.513 164.037 1.00 177.64 ? 534 HIS A O   1 
ATOM   3975 C CB  . HIS A 1 533 ? 140.469 176.145 164.180 1.00 172.14 ? 534 HIS A CB  1 
ATOM   3976 C CG  . HIS A 1 533 ? 141.665 176.952 164.572 1.00 176.74 ? 534 HIS A CG  1 
ATOM   3977 N ND1 . HIS A 1 533 ? 142.006 177.184 165.887 1.00 176.24 ? 534 HIS A ND1 1 
ATOM   3978 C CD2 . HIS A 1 533 ? 142.596 177.590 163.824 1.00 181.75 ? 534 HIS A CD2 1 
ATOM   3979 C CE1 . HIS A 1 533 ? 143.099 177.924 165.932 1.00 183.60 ? 534 HIS A CE1 1 
ATOM   3980 N NE2 . HIS A 1 533 ? 143.477 178.184 164.693 1.00 184.53 ? 534 HIS A NE2 1 
ATOM   3981 N N   . ILE A 1 534 ? 139.373 172.579 164.291 1.00 179.22 ? 535 ILE A N   1 
ATOM   3982 C CA  . ILE A 1 534 ? 138.188 171.728 164.257 1.00 181.12 ? 535 ILE A CA  1 
ATOM   3983 C C   . ILE A 1 534 ? 138.026 171.092 165.631 1.00 177.39 ? 535 ILE A C   1 
ATOM   3984 O O   . ILE A 1 534 ? 138.955 170.455 166.140 1.00 171.24 ? 535 ILE A O   1 
ATOM   3985 C CB  . ILE A 1 534 ? 138.290 170.658 163.154 1.00 181.86 ? 535 ILE A CB  1 
ATOM   3986 C CG1 . ILE A 1 534 ? 138.325 171.290 161.754 1.00 181.49 ? 535 ILE A CG1 1 
ATOM   3987 C CG2 . ILE A 1 534 ? 137.135 169.671 163.252 1.00 180.57 ? 535 ILE A CG2 1 
ATOM   3988 C CD1 . ILE A 1 534 ? 137.369 172.457 161.539 1.00 179.67 ? 535 ILE A CD1 1 
ATOM   3989 N N   . LYS A 1 535 ? 136.854 171.277 166.234 1.00 177.03 ? 536 LYS A N   1 
ATOM   3990 C CA  . LYS A 1 535 ? 136.579 170.728 167.555 1.00 177.93 ? 536 LYS A CA  1 
ATOM   3991 C C   . LYS A 1 535 ? 136.184 169.261 167.429 1.00 180.69 ? 536 LYS A C   1 
ATOM   3992 O O   . LYS A 1 535 ? 135.309 168.913 166.629 1.00 178.88 ? 536 LYS A O   1 
ATOM   3993 C CB  . LYS A 1 535 ? 135.477 171.528 168.244 1.00 180.24 ? 536 LYS A CB  1 
ATOM   3994 C CG  . LYS A 1 535 ? 135.799 173.005 168.423 1.00 185.06 ? 536 LYS A CG  1 
ATOM   3995 C CD  . LYS A 1 535 ? 137.136 173.202 169.122 1.00 185.01 ? 536 LYS A CD  1 
ATOM   3996 C CE  . LYS A 1 535 ? 137.607 174.644 169.018 1.00 189.59 ? 536 LYS A CE  1 
ATOM   3997 N NZ  . LYS A 1 535 ? 138.941 174.838 169.651 1.00 191.93 ? 536 LYS A NZ  1 
ATOM   3998 N N   . SER A 1 536 ? 136.826 168.405 168.221 1.00 181.81 ? 537 SER A N   1 
ATOM   3999 C CA  . SER A 1 536 ? 136.573 166.972 168.162 1.00 178.78 ? 537 SER A CA  1 
ATOM   4000 C C   . SER A 1 536 ? 135.423 166.596 169.087 1.00 176.46 ? 537 SER A C   1 
ATOM   4001 O O   . SER A 1 536 ? 135.406 166.983 170.259 1.00 178.22 ? 537 SER A O   1 
ATOM   4002 C CB  . SER A 1 536 ? 137.829 166.192 168.549 1.00 176.17 ? 537 SER A CB  1 
ATOM   4003 O OG  . SER A 1 536 ? 138.977 166.708 167.902 1.00 177.40 ? 537 SER A OG  1 
ATOM   4004 N N   . GLN A 1 537 ? 134.466 165.836 168.558 1.00 171.72 ? 538 GLN A N   1 
ATOM   4005 C CA  . GLN A 1 537 ? 133.371 165.313 169.361 1.00 166.32 ? 538 GLN A CA  1 
ATOM   4006 C C   . GLN A 1 537 ? 132.935 163.978 168.769 1.00 162.96 ? 538 GLN A C   1 
ATOM   4007 O O   . GLN A 1 537 ? 133.491 163.506 167.775 1.00 160.33 ? 538 GLN A O   1 
ATOM   4008 C CB  . GLN A 1 537 ? 132.223 166.328 169.466 1.00 162.68 ? 538 GLN A CB  1 
ATOM   4009 C CG  . GLN A 1 537 ? 131.766 166.946 168.158 1.00 160.17 ? 538 GLN A CG  1 
ATOM   4010 C CD  . GLN A 1 537 ? 130.668 166.149 167.496 1.00 158.89 ? 538 GLN A CD  1 
ATOM   4011 O OE1 . GLN A 1 537 ? 130.134 165.211 168.083 1.00 161.18 ? 538 GLN A OE1 1 
ATOM   4012 N NE2 . GLN A 1 537 ? 130.304 166.534 166.279 1.00 158.53 ? 538 GLN A NE2 1 
ATOM   4013 N N   . LEU A 1 538 ? 131.933 163.365 169.407 1.00 164.02 ? 539 LEU A N   1 
ATOM   4014 C CA  . LEU A 1 538 ? 131.614 161.966 169.127 1.00 163.85 ? 539 LEU A CA  1 
ATOM   4015 C C   . LEU A 1 538 ? 130.904 161.794 167.788 1.00 158.53 ? 539 LEU A C   1 
ATOM   4016 O O   . LEU A 1 538 ? 131.193 160.848 167.046 1.00 153.75 ? 539 LEU A O   1 
ATOM   4017 C CB  . LEU A 1 538 ? 130.762 161.388 170.257 1.00 163.89 ? 539 LEU A CB  1 
ATOM   4018 C CG  . LEU A 1 538 ? 130.634 159.863 170.278 1.00 169.17 ? 539 LEU A CG  1 
ATOM   4019 C CD1 . LEU A 1 538 ? 131.977 159.213 170.580 1.00 167.90 ? 539 LEU A CD1 1 
ATOM   4020 C CD2 . LEU A 1 538 ? 129.581 159.423 171.283 1.00 168.89 ? 539 LEU A CD2 1 
ATOM   4021 N N   . TRP A 1 539 ? 129.961 162.685 167.470 1.00 159.50 ? 540 TRP A N   1 
ATOM   4022 C CA  . TRP A 1 539 ? 129.195 162.560 166.232 1.00 158.29 ? 540 TRP A CA  1 
ATOM   4023 C C   . TRP A 1 539 ? 130.079 162.855 165.022 1.00 157.49 ? 540 TRP A C   1 
ATOM   4024 O O   . TRP A 1 539 ? 129.913 162.249 163.956 1.00 154.00 ? 540 TRP A O   1 
ATOM   4025 C CB  . TRP A 1 539 ? 127.981 163.496 166.305 1.00 160.96 ? 540 TRP A CB  1 
ATOM   4026 C CG  . TRP A 1 539 ? 127.024 163.540 165.133 1.00 166.52 ? 540 TRP A CG  1 
ATOM   4027 C CD1 . TRP A 1 539 ? 126.913 162.646 164.106 1.00 167.75 ? 540 TRP A CD1 1 
ATOM   4028 C CD2 . TRP A 1 539 ? 126.026 164.541 164.897 1.00 171.52 ? 540 TRP A CD2 1 
ATOM   4029 N NE1 . TRP A 1 539 ? 125.920 163.035 163.242 1.00 174.95 ? 540 TRP A NE1 1 
ATOM   4030 C CE2 . TRP A 1 539 ? 125.358 164.194 163.706 1.00 176.37 ? 540 TRP A CE2 1 
ATOM   4031 C CE3 . TRP A 1 539 ? 125.635 165.699 165.576 1.00 169.27 ? 540 TRP A CE3 1 
ATOM   4032 C CZ2 . TRP A 1 539 ? 124.322 164.964 163.179 1.00 176.93 ? 540 TRP A CZ2 1 
ATOM   4033 C CZ3 . TRP A 1 539 ? 124.608 166.462 165.052 1.00 171.03 ? 540 TRP A CZ3 1 
ATOM   4034 C CH2 . TRP A 1 539 ? 123.963 166.091 163.866 1.00 174.49 ? 540 TRP A CH2 1 
ATOM   4035 N N   . LEU A 1 540 ? 131.047 163.763 165.181 1.00 157.64 ? 541 LEU A N   1 
ATOM   4036 C CA  . LEU A 1 540 ? 132.035 164.003 164.133 1.00 152.44 ? 541 LEU A CA  1 
ATOM   4037 C C   . LEU A 1 540 ? 132.938 162.791 163.928 1.00 147.22 ? 541 LEU A C   1 
ATOM   4038 O O   . LEU A 1 540 ? 133.306 162.469 162.793 1.00 141.25 ? 541 LEU A O   1 
ATOM   4039 C CB  . LEU A 1 540 ? 132.871 165.236 164.475 1.00 157.16 ? 541 LEU A CB  1 
ATOM   4040 C CG  . LEU A 1 540 ? 133.927 165.674 163.459 1.00 161.36 ? 541 LEU A CG  1 
ATOM   4041 C CD1 . LEU A 1 540 ? 133.279 166.074 162.141 1.00 156.83 ? 541 LEU A CD1 1 
ATOM   4042 C CD2 . LEU A 1 540 ? 134.767 166.811 164.017 1.00 166.79 ? 541 LEU A CD2 1 
ATOM   4043 N N   . LEU A 1 541 ? 133.305 162.110 165.019 1.00 149.57 ? 542 LEU A N   1 
ATOM   4044 C CA  . LEU A 1 541 ? 134.180 160.944 164.927 1.00 145.37 ? 542 LEU A CA  1 
ATOM   4045 C C   . LEU A 1 541 ? 133.473 159.767 164.264 1.00 140.37 ? 542 LEU A C   1 
ATOM   4046 O O   . LEU A 1 541 ? 134.104 158.972 163.557 1.00 137.19 ? 542 LEU A O   1 
ATOM   4047 C CB  . LEU A 1 541 ? 134.676 160.559 166.322 1.00 150.42 ? 542 LEU A CB  1 
ATOM   4048 C CG  . LEU A 1 541 ? 135.662 159.396 166.450 1.00 145.35 ? 542 LEU A CG  1 
ATOM   4049 C CD1 . LEU A 1 541 ? 136.959 159.712 165.725 1.00 143.16 ? 542 LEU A CD1 1 
ATOM   4050 C CD2 . LEU A 1 541 ? 135.926 159.075 167.912 1.00 148.45 ? 542 LEU A CD2 1 
ATOM   4051 N N   . VAL A 1 542 ? 132.165 159.633 164.497 1.00 143.14 ? 543 VAL A N   1 
ATOM   4052 C CA  . VAL A 1 542 ? 131.381 158.590 163.838 1.00 147.55 ? 543 VAL A CA  1 
ATOM   4053 C C   . VAL A 1 542 ? 131.289 158.866 162.341 1.00 141.82 ? 543 VAL A C   1 
ATOM   4054 O O   . VAL A 1 542 ? 131.445 157.962 161.511 1.00 141.21 ? 543 VAL A O   1 
ATOM   4055 C CB  . VAL A 1 542 ? 129.989 158.483 164.493 1.00 152.87 ? 543 VAL A CB  1 
ATOM   4056 C CG1 . VAL A 1 542 ? 129.037 157.632 163.660 1.00 146.27 ? 543 VAL A CG1 1 
ATOM   4057 C CG2 . VAL A 1 542 ? 130.111 157.912 165.899 1.00 151.65 ? 543 VAL A CG2 1 
ATOM   4058 N N   . LEU A 1 543 ? 131.071 160.133 161.977 1.00 141.14 ? 544 LEU A N   1 
ATOM   4059 C CA  . LEU A 1 543 ? 130.876 160.492 160.575 1.00 138.09 ? 544 LEU A CA  1 
ATOM   4060 C C   . LEU A 1 543 ? 132.173 160.386 159.779 1.00 134.56 ? 544 LEU A C   1 
ATOM   4061 O O   . LEU A 1 543 ? 132.156 159.964 158.619 1.00 133.08 ? 544 LEU A O   1 
ATOM   4062 C CB  . LEU A 1 543 ? 130.280 161.903 160.488 1.00 145.45 ? 544 LEU A CB  1 
ATOM   4063 C CG  . LEU A 1 543 ? 129.768 162.536 159.183 1.00 146.57 ? 544 LEU A CG  1 
ATOM   4064 C CD1 . LEU A 1 543 ? 128.669 163.529 159.521 1.00 141.30 ? 544 LEU A CD1 1 
ATOM   4065 C CD2 . LEU A 1 543 ? 130.853 163.258 158.385 1.00 145.65 ? 544 LEU A CD2 1 
ATOM   4066 N N   . ILE A 1 544 ? 133.305 160.760 160.376 1.00 136.02 ? 545 ILE A N   1 
ATOM   4067 C CA  . ILE A 1 544 ? 134.545 160.813 159.605 1.00 135.48 ? 545 ILE A CA  1 
ATOM   4068 C C   . ILE A 1 544 ? 135.144 159.414 159.429 1.00 136.12 ? 545 ILE A C   1 
ATOM   4069 O O   . ILE A 1 544 ? 135.903 159.173 158.483 1.00 131.69 ? 545 ILE A O   1 
ATOM   4070 C CB  . ILE A 1 544 ? 135.531 161.801 160.266 1.00 138.32 ? 545 ILE A CB  1 
ATOM   4071 C CG1 . ILE A 1 544 ? 136.679 162.172 159.321 1.00 136.67 ? 545 ILE A CG1 1 
ATOM   4072 C CG2 . ILE A 1 544 ? 136.104 161.239 161.561 1.00 136.90 ? 545 ILE A CG2 1 
ATOM   4073 C CD1 . ILE A 1 544 ? 136.241 162.958 158.106 1.00 135.15 ? 545 ILE A CD1 1 
ATOM   4074 N N   . LEU A 1 545 ? 134.784 158.460 160.291 1.00 135.16 ? 546 LEU A N   1 
ATOM   4075 C CA  . LEU A 1 545 ? 135.383 157.133 160.202 1.00 131.23 ? 546 LEU A CA  1 
ATOM   4076 C C   . LEU A 1 545 ? 134.639 156.243 159.211 1.00 128.91 ? 546 LEU A C   1 
ATOM   4077 O O   . LEU A 1 545 ? 135.256 155.401 158.548 1.00 125.01 ? 546 LEU A O   1 
ATOM   4078 C CB  . LEU A 1 545 ? 135.426 156.486 161.588 1.00 133.72 ? 546 LEU A CB  1 
ATOM   4079 C CG  . LEU A 1 545 ? 136.109 155.120 161.697 1.00 138.78 ? 546 LEU A CG  1 
ATOM   4080 C CD1 . LEU A 1 545 ? 137.580 155.227 161.324 1.00 138.45 ? 546 LEU A CD1 1 
ATOM   4081 C CD2 . LEU A 1 545 ? 135.952 154.544 163.088 1.00 144.12 ? 546 LEU A CD2 1 
ATOM   4082 N N   . VAL A 1 546 ? 133.322 156.421 159.082 1.00 128.80 ? 547 VAL A N   1 
ATOM   4083 C CA  . VAL A 1 546 ? 132.565 155.606 158.135 1.00 126.17 ? 547 VAL A CA  1 
ATOM   4084 C C   . VAL A 1 546 ? 132.828 156.054 156.702 1.00 130.25 ? 547 VAL A C   1 
ATOM   4085 O O   . VAL A 1 546 ? 132.632 155.278 155.758 1.00 133.58 ? 547 VAL A O   1 
ATOM   4086 C CB  . VAL A 1 546 ? 131.062 155.631 158.475 1.00 132.00 ? 547 VAL A CB  1 
ATOM   4087 C CG1 . VAL A 1 546 ? 130.819 155.002 159.838 1.00 134.87 ? 547 VAL A CG1 1 
ATOM   4088 C CG2 . VAL A 1 546 ? 130.510 157.049 158.430 1.00 136.03 ? 547 VAL A CG2 1 
ATOM   4089 N N   . VAL A 1 547 ? 133.262 157.302 156.508 1.00 130.20 ? 548 VAL A N   1 
ATOM   4090 C CA  . VAL A 1 547 ? 133.737 157.737 155.199 1.00 128.75 ? 548 VAL A CA  1 
ATOM   4091 C C   . VAL A 1 547 ? 135.065 157.060 154.873 1.00 124.79 ? 548 VAL A C   1 
ATOM   4092 O O   . VAL A 1 547 ? 135.330 156.697 153.719 1.00 128.60 ? 548 VAL A O   1 
ATOM   4093 C CB  . VAL A 1 547 ? 133.831 159.277 155.159 1.00 133.44 ? 548 VAL A CB  1 
ATOM   4094 C CG1 . VAL A 1 547 ? 134.431 159.780 153.851 1.00 130.37 ? 548 VAL A CG1 1 
ATOM   4095 C CG2 . VAL A 1 547 ? 132.453 159.886 155.349 1.00 134.20 ? 548 VAL A CG2 1 
ATOM   4096 N N   . SER A 1 548 ? 135.906 156.848 155.892 1.00 125.52 ? 549 SER A N   1 
ATOM   4097 C CA  . SER A 1 548 ? 137.184 156.169 155.690 1.00 129.10 ? 549 SER A CA  1 
ATOM   4098 C C   . SER A 1 548 ? 137.000 154.704 155.315 1.00 121.91 ? 549 SER A C   1 
ATOM   4099 O O   . SER A 1 548 ? 137.854 154.131 154.631 1.00 122.28 ? 549 SER A O   1 
ATOM   4100 C CB  . SER A 1 548 ? 138.045 156.286 156.947 1.00 132.26 ? 549 SER A CB  1 
ATOM   4101 O OG  . SER A 1 548 ? 139.237 155.531 156.820 1.00 135.69 ? 549 SER A OG  1 
ATOM   4102 N N   . GLY A 1 549 ? 135.908 154.080 155.763 1.00 121.27 ? 550 GLY A N   1 
ATOM   4103 C CA  . GLY A 1 549 ? 135.575 152.749 155.286 1.00 121.63 ? 550 GLY A CA  1 
ATOM   4104 C C   . GLY A 1 549 ? 135.186 152.726 153.822 1.00 119.48 ? 550 GLY A C   1 
ATOM   4105 O O   . GLY A 1 549 ? 135.460 151.749 153.119 1.00 117.97 ? 550 GLY A O   1 
ATOM   4106 N N   . LEU A 1 550 ? 134.528 153.788 153.349 1.00 120.22 ? 551 LEU A N   1 
ATOM   4107 C CA  . LEU A 1 550 ? 134.184 153.902 151.935 1.00 122.11 ? 551 LEU A CA  1 
ATOM   4108 C C   . LEU A 1 550 ? 135.429 154.074 151.072 1.00 119.84 ? 551 LEU A C   1 
ATOM   4109 O O   . LEU A 1 550 ? 135.503 153.534 149.963 1.00 118.57 ? 551 LEU A O   1 
ATOM   4110 C CB  . LEU A 1 550 ? 133.225 155.075 151.732 1.00 125.67 ? 551 LEU A CB  1 
ATOM   4111 C CG  . LEU A 1 550 ? 132.672 155.359 150.333 1.00 134.17 ? 551 LEU A CG  1 
ATOM   4112 C CD1 . LEU A 1 550 ? 131.825 154.203 149.836 1.00 127.54 ? 551 LEU A CD1 1 
ATOM   4113 C CD2 . LEU A 1 550 ? 131.874 156.655 150.323 1.00 136.02 ? 551 LEU A CD2 1 
ATOM   4114 N N   . SER A 1 551 ? 136.413 154.828 151.563 1.00 123.08 ? 552 SER A N   1 
ATOM   4115 C CA  . SER A 1 551 ? 137.630 155.076 150.798 1.00 122.48 ? 552 SER A CA  1 
ATOM   4116 C C   . SER A 1 551 ? 138.569 153.876 150.810 1.00 121.94 ? 552 SER A C   1 
ATOM   4117 O O   . SER A 1 551 ? 139.224 153.592 149.801 1.00 121.78 ? 552 SER A O   1 
ATOM   4118 C CB  . SER A 1 551 ? 138.347 156.309 151.346 1.00 124.15 ? 552 SER A CB  1 
ATOM   4119 O OG  . SER A 1 551 ? 139.076 155.993 152.519 1.00 124.41 ? 552 SER A OG  1 
ATOM   4120 N N   . ALA A 1 552 ? 138.664 153.177 151.944 1.00 120.44 ? 553 ALA A N   1 
ATOM   4121 C CA  . ALA A 1 552 ? 139.600 152.061 152.053 1.00 116.56 ? 553 ALA A CA  1 
ATOM   4122 C C   . ALA A 1 552 ? 139.134 150.862 151.241 1.00 117.89 ? 553 ALA A C   1 
ATOM   4123 O O   . ALA A 1 552 ? 139.951 150.160 150.635 1.00 121.17 ? 553 ALA A O   1 
ATOM   4124 C CB  . ALA A 1 552 ? 139.791 151.671 153.518 1.00 116.04 ? 553 ALA A CB  1 
ATOM   4125 N N   . GLY A 1 553 ? 137.823 150.611 151.213 1.00 116.14 ? 554 GLY A N   1 
ATOM   4126 C CA  . GLY A 1 553 ? 137.307 149.506 150.424 1.00 116.78 ? 554 GLY A CA  1 
ATOM   4127 C C   . GLY A 1 553 ? 137.334 149.776 148.935 1.00 115.34 ? 554 GLY A C   1 
ATOM   4128 O O   . GLY A 1 553 ? 137.311 148.840 148.130 1.00 112.22 ? 554 GLY A O   1 
ATOM   4129 N N   . MET A 1 554 ? 137.387 151.050 148.546 1.00 117.50 ? 555 MET A N   1 
ATOM   4130 C CA  . MET A 1 554 ? 137.434 151.395 147.131 1.00 118.29 ? 555 MET A CA  1 
ATOM   4131 C C   . MET A 1 554 ? 138.852 151.263 146.579 1.00 113.65 ? 555 MET A C   1 
ATOM   4132 O O   . MET A 1 554 ? 139.039 151.133 145.364 1.00 113.67 ? 555 MET A O   1 
ATOM   4133 C CB  . MET A 1 554 ? 136.846 152.805 146.954 1.00 115.95 ? 555 MET A CB  1 
ATOM   4134 C CG  . MET A 1 554 ? 136.729 153.337 145.533 1.00 116.22 ? 555 MET A CG  1 
ATOM   4135 S SD  . MET A 1 554 ? 135.886 154.933 145.424 1.00 133.66 ? 555 MET A SD  1 
ATOM   4136 C CE  . MET A 1 554 ? 137.078 156.053 146.127 1.00 120.81 ? 555 MET A CE  1 
ATOM   4137 N N   . SER A 1 555 ? 139.854 151.218 147.455 1.00 112.88 ? 556 SER A N   1 
ATOM   4138 C CA  . SER A 1 555 ? 141.238 151.099 147.019 1.00 114.58 ? 556 SER A CA  1 
ATOM   4139 C C   . SER A 1 555 ? 141.831 149.713 147.239 1.00 114.10 ? 556 SER A C   1 
ATOM   4140 O O   . SER A 1 555 ? 142.903 149.426 146.697 1.00 120.29 ? 556 SER A O   1 
ATOM   4141 C CB  . SER A 1 555 ? 142.108 152.134 147.739 1.00 119.13 ? 556 SER A CB  1 
ATOM   4142 O OG  . SER A 1 555 ? 141.798 152.189 149.121 1.00 118.75 ? 556 SER A OG  1 
ATOM   4143 N N   . ILE A 1 556 ? 141.176 148.851 148.018 1.00 112.81 ? 557 ILE A N   1 
ATOM   4144 C CA  . ILE A 1 556 ? 141.768 147.551 148.320 1.00 113.15 ? 557 ILE A CA  1 
ATOM   4145 C C   . ILE A 1 556 ? 141.275 146.471 147.356 1.00 113.07 ? 557 ILE A C   1 
ATOM   4146 O O   . ILE A 1 556 ? 141.971 145.471 147.141 1.00 110.44 ? 557 ILE A O   1 
ATOM   4147 C CB  . ILE A 1 556 ? 141.500 147.199 149.799 1.00 113.98 ? 557 ILE A CB  1 
ATOM   4148 C CG1 . ILE A 1 556 ? 142.343 146.008 150.269 1.00 117.29 ? 557 ILE A CG1 1 
ATOM   4149 C CG2 . ILE A 1 556 ? 140.028 146.908 150.045 1.00 114.48 ? 557 ILE A CG2 1 
ATOM   4150 C CD1 . ILE A 1 556 ? 142.360 145.826 151.771 1.00 121.87 ? 557 ILE A CD1 1 
ATOM   4151 N N   . ILE A 1 557 ? 140.116 146.658 146.732 1.00 120.02 ? 558 ILE A N   1 
ATOM   4152 C CA  . ILE A 1 557 ? 139.568 145.658 145.816 1.00 118.90 ? 558 ILE A CA  1 
ATOM   4153 C C   . ILE A 1 557 ? 140.264 145.663 144.448 1.00 115.82 ? 558 ILE A C   1 
ATOM   4154 O O   . ILE A 1 557 ? 140.753 144.593 144.054 1.00 115.62 ? 558 ILE A O   1 
ATOM   4155 C CB  . ILE A 1 557 ? 138.036 145.801 145.695 1.00 117.67 ? 558 ILE A CB  1 
ATOM   4156 C CG1 . ILE A 1 557 ? 137.358 145.344 146.988 1.00 113.82 ? 558 ILE A CG1 1 
ATOM   4157 C CG2 . ILE A 1 557 ? 137.503 145.007 144.511 1.00 121.23 ? 558 ILE A CG2 1 
ATOM   4158 C CD1 . ILE A 1 557 ? 137.482 143.860 147.258 1.00 115.60 ? 558 ILE A CD1 1 
ATOM   4159 N N   . PRO A 1 558 ? 140.380 146.758 143.682 1.00 118.70 ? 559 PRO A N   1 
ATOM   4160 C CA  . PRO A 1 558 ? 140.930 146.618 142.327 1.00 122.56 ? 559 PRO A CA  1 
ATOM   4161 C C   . PRO A 1 558 ? 142.449 146.583 142.243 1.00 118.45 ? 559 PRO A C   1 
ATOM   4162 O O   . PRO A 1 558 ? 142.985 146.750 141.145 1.00 117.32 ? 559 PRO A O   1 
ATOM   4163 C CB  . PRO A 1 558 ? 140.383 147.860 141.610 1.00 119.74 ? 559 PRO A CB  1 
ATOM   4164 C CG  . PRO A 1 558 ? 140.354 148.869 142.634 1.00 110.60 ? 559 PRO A CG  1 
ATOM   4165 C CD  . PRO A 1 558 ? 140.016 148.178 143.917 1.00 117.03 ? 559 PRO A CD  1 
ATOM   4166 N N   . THR A 1 559 ? 143.167 146.377 143.349 1.00 115.83 ? 560 THR A N   1 
ATOM   4167 C CA  . THR A 1 559 ? 144.621 146.287 143.262 1.00 112.89 ? 560 THR A CA  1 
ATOM   4168 C C   . THR A 1 559 ? 145.080 144.881 142.888 1.00 111.98 ? 560 THR A C   1 
ATOM   4169 O O   . THR A 1 559 ? 146.222 144.697 142.456 1.00 114.76 ? 560 THR A O   1 
ATOM   4170 C CB  . THR A 1 559 ? 145.263 146.733 144.579 1.00 115.22 ? 560 THR A CB  1 
ATOM   4171 O OG1 . THR A 1 559 ? 146.687 146.776 144.429 1.00 118.30 ? 560 THR A OG1 1 
ATOM   4172 C CG2 . THR A 1 559 ? 144.914 145.787 145.702 1.00 115.47 ? 560 THR A CG2 1 
ATOM   4173 N N   . PHE A 1 560 ? 144.214 143.880 143.044 1.00 108.48 ? 561 PHE A N   1 
ATOM   4174 C CA  . PHE A 1 560 ? 144.561 142.530 142.601 1.00 109.68 ? 561 PHE A CA  1 
ATOM   4175 C C   . PHE A 1 560 ? 144.362 142.331 141.094 1.00 117.25 ? 561 PHE A C   1 
ATOM   4176 O O   . PHE A 1 560 ? 145.258 141.742 140.465 1.00 122.15 ? 561 PHE A O   1 
ATOM   4177 C CB  . PHE A 1 560 ? 143.801 141.497 143.451 1.00 115.31 ? 561 PHE A CB  1 
ATOM   4178 C CG  . PHE A 1 560 ? 144.107 140.053 143.112 1.00 116.04 ? 561 PHE A CG  1 
ATOM   4179 C CD1 . PHE A 1 560 ? 145.395 139.633 142.815 1.00 116.25 ? 561 PHE A CD1 1 
ATOM   4180 C CD2 . PHE A 1 560 ? 143.087 139.117 143.074 1.00 118.57 ? 561 PHE A CD2 1 
ATOM   4181 C CE1 . PHE A 1 560 ? 145.649 138.308 142.503 1.00 122.19 ? 561 PHE A CE1 1 
ATOM   4182 C CE2 . PHE A 1 560 ? 143.336 137.798 142.761 1.00 123.68 ? 561 PHE A CE2 1 
ATOM   4183 C CZ  . PHE A 1 560 ? 144.619 137.394 142.475 1.00 127.51 ? 561 PHE A CZ  1 
ATOM   4184 N N   . PRO A 1 561 ? 143.259 142.766 140.446 1.00 115.70 ? 562 PRO A N   1 
ATOM   4185 C CA  . PRO A 1 561 ? 143.228 142.637 138.977 1.00 114.06 ? 562 PRO A CA  1 
ATOM   4186 C C   . PRO A 1 561 ? 144.189 143.562 138.250 1.00 112.96 ? 562 PRO A C   1 
ATOM   4187 O O   . PRO A 1 561 ? 144.509 143.303 137.084 1.00 116.36 ? 562 PRO A O   1 
ATOM   4188 C CB  . PRO A 1 561 ? 141.772 142.963 138.621 1.00 113.78 ? 562 PRO A CB  1 
ATOM   4189 C CG  . PRO A 1 561 ? 141.018 142.687 139.819 1.00 110.09 ? 562 PRO A CG  1 
ATOM   4190 C CD  . PRO A 1 561 ? 141.903 143.104 140.936 1.00 112.45 ? 562 PRO A CD  1 
ATOM   4191 N N   . GLU A 1 562 ? 144.648 144.639 138.892 1.00 113.03 ? 563 GLU A N   1 
ATOM   4192 C CA  . GLU A 1 562 ? 145.601 145.536 138.245 1.00 113.25 ? 563 GLU A CA  1 
ATOM   4193 C C   . GLU A 1 562 ? 146.976 144.886 138.125 1.00 114.87 ? 563 GLU A C   1 
ATOM   4194 O O   . GLU A 1 562 ? 147.648 145.030 137.096 1.00 118.58 ? 563 GLU A O   1 
ATOM   4195 C CB  . GLU A 1 562 ? 145.685 146.851 139.022 1.00 118.43 ? 563 GLU A CB  1 
ATOM   4196 C CG  . GLU A 1 562 ? 146.702 147.862 138.496 1.00 122.24 ? 563 GLU A CG  1 
ATOM   4197 C CD  . GLU A 1 562 ? 146.642 148.043 136.991 1.00 117.59 ? 563 GLU A CD  1 
ATOM   4198 O OE1 . GLU A 1 562 ? 145.557 148.375 136.471 1.00 122.93 ? 563 GLU A OE1 1 
ATOM   4199 O OE2 . GLU A 1 562 ? 147.684 147.857 136.328 1.00 110.07 ? 563 GLU A OE2 1 
ATOM   4200 N N   . ILE A 1 563 ? 147.409 144.168 139.163 1.00 109.49 ? 564 ILE A N   1 
ATOM   4201 C CA  . ILE A 1 563 ? 148.697 143.483 139.111 1.00 107.88 ? 564 ILE A CA  1 
ATOM   4202 C C   . ILE A 1 563 ? 148.622 142.293 138.156 1.00 113.34 ? 564 ILE A C   1 
ATOM   4203 O O   . ILE A 1 563 ? 149.581 141.997 137.431 1.00 116.88 ? 564 ILE A O   1 
ATOM   4204 C CB  . ILE A 1 563 ? 149.131 143.076 140.532 1.00 103.77 ? 564 ILE A CB  1 
ATOM   4205 C CG1 . ILE A 1 563 ? 149.326 144.324 141.392 1.00 106.43 ? 564 ILE A CG1 1 
ATOM   4206 C CG2 . ILE A 1 563 ? 150.469 142.354 140.509 1.00 111.24 ? 564 ILE A CG2 1 
ATOM   4207 C CD1 . ILE A 1 563 ? 149.781 144.040 142.811 1.00 109.12 ? 564 ILE A CD1 1 
ATOM   4208 N N   . LEU A 1 564 ? 147.471 141.609 138.124 1.00 111.80 ? 565 LEU A N   1 
ATOM   4209 C CA  . LEU A 1 564 ? 147.243 140.555 137.136 1.00 113.55 ? 565 LEU A CA  1 
ATOM   4210 C C   . LEU A 1 564 ? 147.226 141.108 135.717 1.00 114.49 ? 565 LEU A C   1 
ATOM   4211 O O   . LEU A 1 564 ? 147.675 140.439 134.779 1.00 115.33 ? 565 LEU A O   1 
ATOM   4212 C CB  . LEU A 1 564 ? 145.931 139.827 137.428 1.00 116.94 ? 565 LEU A CB  1 
ATOM   4213 C CG  . LEU A 1 564 ? 145.838 138.975 138.692 1.00 128.17 ? 565 LEU A CG  1 
ATOM   4214 C CD1 . LEU A 1 564 ? 144.420 138.469 138.879 1.00 127.21 ? 565 LEU A CD1 1 
ATOM   4215 C CD2 . LEU A 1 564 ? 146.802 137.810 138.586 1.00 127.29 ? 565 LEU A CD2 1 
ATOM   4216 N N   . SER A 1 565 ? 146.690 142.318 135.535 1.00 112.97 ? 566 SER A N   1 
ATOM   4217 C CA  . SER A 1 565 ? 146.748 142.962 134.227 1.00 109.06 ? 566 SER A CA  1 
ATOM   4218 C C   . SER A 1 565 ? 148.172 143.367 133.875 1.00 110.78 ? 566 SER A C   1 
ATOM   4219 O O   . SER A 1 565 ? 148.577 143.270 132.713 1.00 112.45 ? 566 SER A O   1 
ATOM   4220 C CB  . SER A 1 565 ? 145.825 144.178 134.193 1.00 108.35 ? 566 SER A CB  1 
ATOM   4221 O OG  . SER A 1 565 ? 144.470 143.794 134.342 1.00 114.80 ? 566 SER A OG  1 
ATOM   4222 N N   . CYS A 1 566 ? 148.943 143.822 134.867 1.00 113.46 ? 567 CYS A N   1 
ATOM   4223 C CA  . CYS A 1 566 ? 150.309 144.272 134.614 1.00 114.60 ? 567 CYS A CA  1 
ATOM   4224 C C   . CYS A 1 566 ? 151.228 143.113 134.251 1.00 111.27 ? 567 CYS A C   1 
ATOM   4225 O O   . CYS A 1 566 ? 152.175 143.290 133.475 1.00 110.31 ? 567 CYS A O   1 
ATOM   4226 C CB  . CYS A 1 566 ? 150.839 145.016 135.841 1.00 115.46 ? 567 CYS A CB  1 
ATOM   4227 S SG  . CYS A 1 566 ? 152.610 145.391 135.839 1.00 128.24 ? 567 CYS A SG  1 
ATOM   4228 N N   . ALA A 1 567 ? 150.955 141.921 134.784 1.00 112.47 ? 568 ALA A N   1 
ATOM   4229 C CA  . ALA A 1 567 ? 151.785 140.759 134.486 1.00 119.67 ? 568 ALA A CA  1 
ATOM   4230 C C   . ALA A 1 567 ? 151.604 140.300 133.043 1.00 117.17 ? 568 ALA A C   1 
ATOM   4231 O O   . ALA A 1 567 ? 152.582 139.998 132.352 1.00 123.72 ? 568 ALA A O   1 
ATOM   4232 C CB  . ALA A 1 567 ? 151.461 139.624 135.457 1.00 122.95 ? 568 ALA A CB  1 
ATOM   4233 N N   . HIS A 1 568 ? 150.357 140.256 132.567 1.00 114.54 ? 569 HIS A N   1 
ATOM   4234 C CA  . HIS A 1 568 ? 150.092 139.717 131.237 1.00 115.39 ? 569 HIS A CA  1 
ATOM   4235 C C   . HIS A 1 568 ? 150.507 140.679 130.129 1.00 114.52 ? 569 HIS A C   1 
ATOM   4236 O O   . HIS A 1 568 ? 150.846 140.235 129.027 1.00 118.91 ? 569 HIS A O   1 
ATOM   4237 C CB  . HIS A 1 568 ? 148.614 139.357 131.106 1.00 120.84 ? 569 HIS A CB  1 
ATOM   4238 C CG  . HIS A 1 568 ? 148.231 138.110 131.840 1.00 124.69 ? 569 HIS A CG  1 
ATOM   4239 N ND1 . HIS A 1 568 ? 149.155 137.308 132.474 1.00 124.17 ? 569 HIS A ND1 1 
ATOM   4240 C CD2 . HIS A 1 568 ? 147.026 137.531 132.047 1.00 125.39 ? 569 HIS A CD2 1 
ATOM   4241 C CE1 . HIS A 1 568 ? 148.535 136.286 133.036 1.00 121.16 ? 569 HIS A CE1 1 
ATOM   4242 N NE2 . HIS A 1 568 ? 147.242 136.399 132.794 1.00 120.63 ? 569 HIS A NE2 1 
ATOM   4243 N N   . GLU A 1 569 ? 150.480 141.989 130.390 1.00 114.17 ? 570 GLU A N   1 
ATOM   4244 C CA  . GLU A 1 569 ? 150.944 142.946 129.388 1.00 114.64 ? 570 GLU A CA  1 
ATOM   4245 C C   . GLU A 1 569 ? 152.460 142.913 129.247 1.00 117.98 ? 570 GLU A C   1 
ATOM   4246 O O   . GLU A 1 569 ? 152.998 143.254 128.187 1.00 120.39 ? 570 GLU A O   1 
ATOM   4247 C CB  . GLU A 1 569 ? 150.476 144.358 129.736 1.00 110.29 ? 570 GLU A CB  1 
ATOM   4248 C CG  . GLU A 1 569 ? 148.973 144.538 129.751 1.00 116.45 ? 570 GLU A CG  1 
ATOM   4249 C CD  . GLU A 1 569 ? 148.560 145.895 130.285 1.00 128.76 ? 570 GLU A CD  1 
ATOM   4250 O OE1 . GLU A 1 569 ? 149.302 146.454 131.118 1.00 127.48 ? 570 GLU A OE1 1 
ATOM   4251 O OE2 . GLU A 1 569 ? 147.495 146.401 129.874 1.00 134.15 ? 570 GLU A OE2 1 
ATOM   4252 N N   . ASN A 1 570 ? 153.166 142.523 130.311 1.00 118.17 ? 571 ASN A N   1 
ATOM   4253 C CA  . ASN A 1 570 ? 154.623 142.464 130.258 1.00 114.63 ? 571 ASN A CA  1 
ATOM   4254 C C   . ASN A 1 570 ? 155.088 141.309 129.375 1.00 120.57 ? 571 ASN A C   1 
ATOM   4255 O O   . ASN A 1 570 ? 156.088 141.438 128.659 1.00 126.50 ? 571 ASN A O   1 
ATOM   4256 C CB  . ASN A 1 570 ? 155.174 142.334 131.682 1.00 113.80 ? 571 ASN A CB  1 
ATOM   4257 C CG  . ASN A 1 570 ? 156.683 142.552 131.775 1.00 118.13 ? 571 ASN A CG  1 
ATOM   4258 O OD1 . ASN A 1 570 ? 157.367 142.804 130.785 1.00 123.27 ? 571 ASN A OD1 1 
ATOM   4259 N ND2 . ASN A 1 570 ? 157.205 142.448 132.989 1.00 124.45 ? 571 ASN A ND2 1 
ATOM   4260 N N   . GLY A 1 571 ? 154.359 140.198 129.378 1.00 118.25 ? 572 GLY A N   1 
ATOM   4261 C CA  . GLY A 1 571 ? 154.742 139.050 128.582 1.00 122.88 ? 572 GLY A CA  1 
ATOM   4262 C C   . GLY A 1 571 ? 154.673 137.747 129.347 1.00 135.99 ? 572 GLY A C   1 
ATOM   4263 O O   . GLY A 1 571 ? 155.163 136.715 128.879 1.00 144.37 ? 572 GLY A O   1 
ATOM   4264 N N   . PHE A 1 572 ? 154.068 137.783 130.530 1.00 130.42 ? 573 PHE A N   1 
ATOM   4265 C CA  . PHE A 1 572 ? 153.946 136.586 131.348 1.00 131.57 ? 573 PHE A CA  1 
ATOM   4266 C C   . PHE A 1 572 ? 152.791 135.721 130.852 1.00 128.10 ? 573 PHE A C   1 
ATOM   4267 O O   . PHE A 1 572 ? 151.825 136.212 130.263 1.00 130.48 ? 573 PHE A O   1 
ATOM   4268 C CB  . PHE A 1 572 ? 153.733 136.961 132.815 1.00 131.58 ? 573 PHE A CB  1 
ATOM   4269 C CG  . PHE A 1 572 ? 154.932 137.597 133.474 1.00 134.61 ? 573 PHE A CG  1 
ATOM   4270 C CD1 . PHE A 1 572 ? 156.197 137.520 132.904 1.00 139.52 ? 573 PHE A CD1 1 
ATOM   4271 C CD2 . PHE A 1 572 ? 154.785 138.286 134.668 1.00 131.50 ? 573 PHE A CD2 1 
ATOM   4272 C CE1 . PHE A 1 572 ? 157.287 138.112 133.514 1.00 146.84 ? 573 PHE A CE1 1 
ATOM   4273 C CE2 . PHE A 1 572 ? 155.871 138.879 135.284 1.00 137.21 ? 573 PHE A CE2 1 
ATOM   4274 C CZ  . PHE A 1 572 ? 157.123 138.792 134.706 1.00 145.25 ? 573 PHE A CZ  1 
ATOM   4275 N N   . GLU A 1 573 ? 152.900 134.418 131.096 1.00 129.16 ? 574 GLU A N   1 
ATOM   4276 C CA  . GLU A 1 573 ? 151.924 133.473 130.576 1.00 134.75 ? 574 GLU A CA  1 
ATOM   4277 C C   . GLU A 1 573 ? 150.656 133.483 131.420 1.00 134.52 ? 574 GLU A C   1 
ATOM   4278 O O   . GLU A 1 573 ? 150.638 133.973 132.552 1.00 133.88 ? 574 GLU A O   1 
ATOM   4279 C CB  . GLU A 1 573 ? 152.503 132.057 130.539 1.00 139.79 ? 574 GLU A CB  1 
ATOM   4280 C CG  . GLU A 1 573 ? 152.709 131.415 131.906 1.00 145.43 ? 574 GLU A CG  1 
ATOM   4281 C CD  . GLU A 1 573 ? 154.039 131.758 132.557 1.00 148.10 ? 574 GLU A CD  1 
ATOM   4282 O OE1 . GLU A 1 573 ? 154.707 132.715 132.117 1.00 149.97 ? 574 GLU A OE1 1 
ATOM   4283 O OE2 . GLU A 1 573 ? 154.419 131.062 133.522 1.00 145.23 ? 574 GLU A OE2 1 
ATOM   4284 N N   . GLU A 1 574 ? 149.587 132.932 130.852 1.00 134.71 ? 575 GLU A N   1 
ATOM   4285 C CA  . GLU A 1 574 ? 148.290 132.888 131.510 1.00 131.31 ? 575 GLU A CA  1 
ATOM   4286 C C   . GLU A 1 574 ? 148.067 131.523 132.146 1.00 130.58 ? 575 GLU A C   1 
ATOM   4287 O O   . GLU A 1 574 ? 148.299 130.487 131.517 1.00 132.73 ? 575 GLU A O   1 
ATOM   4288 C CB  . GLU A 1 574 ? 147.165 133.177 130.512 1.00 136.44 ? 575 GLU A CB  1 
ATOM   4289 C CG  . GLU A 1 574 ? 147.138 134.592 129.941 1.00 137.43 ? 575 GLU A CG  1 
ATOM   4290 C CD  . GLU A 1 574 ? 148.071 134.784 128.757 1.00 141.83 ? 575 GLU A CD  1 
ATOM   4291 O OE1 . GLU A 1 574 ? 148.703 133.798 128.322 1.00 145.18 ? 575 GLU A OE1 1 
ATOM   4292 O OE2 . GLU A 1 574 ? 148.172 135.926 128.261 1.00 137.18 ? 575 GLU A OE2 1 
ATOM   4293 N N   . GLY A 1 575 ? 147.616 131.524 133.386 1.00 128.47 ? 576 GLY A N   1 
ATOM   4294 C CA  . GLY A 1 575 ? 147.243 130.287 134.036 1.00 133.61 ? 576 GLY A CA  1 
ATOM   4295 C C   . GLY A 1 575 ? 147.606 130.310 135.517 1.00 133.98 ? 576 GLY A C   1 
ATOM   4296 O O   . GLY A 1 575 ? 147.548 131.355 136.168 1.00 130.19 ? 576 GLY A O   1 
ATOM   4297 N N   . LEU A 1 576 ? 147.979 129.134 136.021 1.00 135.21 ? 577 LEU A N   1 
ATOM   4298 C CA  . LEU A 1 576 ? 148.227 128.908 137.438 1.00 132.93 ? 577 LEU A CA  1 
ATOM   4299 C C   . LEU A 1 576 ? 149.612 129.355 137.885 1.00 131.95 ? 577 LEU A C   1 
ATOM   4300 O O   . LEU A 1 576 ? 149.843 129.493 139.091 1.00 129.47 ? 577 LEU A O   1 
ATOM   4301 C CB  . LEU A 1 576 ? 148.013 127.415 137.751 1.00 134.46 ? 577 LEU A CB  1 
ATOM   4302 C CG  . LEU A 1 576 ? 148.008 126.740 139.128 1.00 135.89 ? 577 LEU A CG  1 
ATOM   4303 C CD1 . LEU A 1 576 ? 147.091 125.540 139.071 1.00 136.13 ? 577 LEU A CD1 1 
ATOM   4304 C CD2 . LEU A 1 576 ? 149.391 126.252 139.502 1.00 137.65 ? 577 LEU A CD2 1 
ATOM   4305 N N   . SER A 1 577 ? 150.524 129.618 136.948 1.00 134.22 ? 578 SER A N   1 
ATOM   4306 C CA  . SER A 1 577 ? 151.885 129.981 137.327 1.00 129.95 ? 578 SER A CA  1 
ATOM   4307 C C   . SER A 1 577 ? 151.967 131.430 137.785 1.00 127.78 ? 578 SER A C   1 
ATOM   4308 O O   . SER A 1 577 ? 152.364 131.710 138.922 1.00 129.17 ? 578 SER A O   1 
ATOM   4309 C CB  . SER A 1 577 ? 152.836 129.728 136.159 1.00 133.80 ? 578 SER A CB  1 
ATOM   4310 O OG  . SER A 1 577 ? 152.339 130.316 134.973 1.00 133.90 ? 578 SER A OG  1 
ATOM   4311 N N   . THR A 1 578 ? 151.599 132.366 136.912 1.00 128.21 ? 579 THR A N   1 
ATOM   4312 C CA  . THR A 1 578 ? 151.738 133.778 137.238 1.00 125.42 ? 579 THR A CA  1 
ATOM   4313 C C   . THR A 1 578 ? 150.655 134.259 138.191 1.00 122.41 ? 579 THR A C   1 
ATOM   4314 O O   . THR A 1 578 ? 150.828 135.292 138.844 1.00 119.71 ? 579 THR A O   1 
ATOM   4315 C CB  . THR A 1 578 ? 151.726 134.609 135.958 1.00 131.46 ? 579 THR A CB  1 
ATOM   4316 O OG1 . THR A 1 578 ? 150.474 134.429 135.285 1.00 131.05 ? 579 THR A OG1 1 
ATOM   4317 C CG2 . THR A 1 578 ? 152.852 134.158 135.047 1.00 135.84 ? 579 THR A CG2 1 
ATOM   4318 N N   . LEU A 1 579 ? 149.537 133.534 138.277 1.00 122.97 ? 580 LEU A N   1 
ATOM   4319 C CA  . LEU A 1 579 ? 148.532 133.837 139.290 1.00 121.09 ? 580 LEU A CA  1 
ATOM   4320 C C   . LEU A 1 579 ? 149.052 133.534 140.688 1.00 116.35 ? 580 LEU A C   1 
ATOM   4321 O O   . LEU A 1 579 ? 148.700 134.229 141.649 1.00 120.66 ? 580 LEU A O   1 
ATOM   4322 C CB  . LEU A 1 579 ? 147.258 133.041 139.005 1.00 122.75 ? 580 LEU A CB  1 
ATOM   4323 C CG  . LEU A 1 579 ? 146.061 133.139 139.951 1.00 124.55 ? 580 LEU A CG  1 
ATOM   4324 C CD1 . LEU A 1 579 ? 145.686 134.588 140.216 1.00 121.24 ? 580 LEU A CD1 1 
ATOM   4325 C CD2 . LEU A 1 579 ? 144.882 132.368 139.382 1.00 122.89 ? 580 LEU A CD2 1 
ATOM   4326 N N   . GLY A 1 580 ? 149.886 132.502 140.819 1.00 118.20 ? 581 GLY A N   1 
ATOM   4327 C CA  . GLY A 1 580 ? 150.446 132.166 142.117 1.00 117.89 ? 581 GLY A CA  1 
ATOM   4328 C C   . GLY A 1 580 ? 151.444 133.187 142.626 1.00 117.82 ? 581 GLY A C   1 
ATOM   4329 O O   . GLY A 1 580 ? 151.504 133.461 143.828 1.00 122.91 ? 581 GLY A O   1 
ATOM   4330 N N   . LEU A 1 581 ? 152.248 133.752 141.726 1.00 119.15 ? 582 LEU A N   1 
ATOM   4331 C CA  . LEU A 1 581 ? 153.261 134.716 142.141 1.00 118.73 ? 582 LEU A CA  1 
ATOM   4332 C C   . LEU A 1 581 ? 152.632 136.053 142.514 1.00 119.22 ? 582 LEU A C   1 
ATOM   4333 O O   . LEU A 1 581 ? 153.128 136.753 143.404 1.00 117.79 ? 582 LEU A O   1 
ATOM   4334 C CB  . LEU A 1 581 ? 154.290 134.895 141.026 1.00 119.57 ? 582 LEU A CB  1 
ATOM   4335 C CG  . LEU A 1 581 ? 154.810 133.597 140.404 1.00 126.61 ? 582 LEU A CG  1 
ATOM   4336 C CD1 . LEU A 1 581 ? 155.438 133.866 139.044 1.00 126.94 ? 582 LEU A CD1 1 
ATOM   4337 C CD2 . LEU A 1 581 ? 155.786 132.885 141.325 1.00 125.57 ? 582 LEU A CD2 1 
ATOM   4338 N N   . VAL A 1 582 ? 151.543 136.423 141.837 1.00 119.68 ? 583 VAL A N   1 
ATOM   4339 C CA  . VAL A 1 582 ? 150.859 137.680 142.125 1.00 116.44 ? 583 VAL A CA  1 
ATOM   4340 C C   . VAL A 1 582 ? 150.138 137.612 143.468 1.00 119.13 ? 583 VAL A C   1 
ATOM   4341 O O   . VAL A 1 582 ? 150.216 138.545 144.278 1.00 122.98 ? 583 VAL A O   1 
ATOM   4342 C CB  . VAL A 1 582 ? 149.901 138.026 140.968 1.00 115.30 ? 583 VAL A CB  1 
ATOM   4343 C CG1 . VAL A 1 582 ? 148.933 139.115 141.363 1.00 113.11 ? 583 VAL A CG1 1 
ATOM   4344 C CG2 . VAL A 1 582 ? 150.692 138.463 139.748 1.00 123.54 ? 583 VAL A CG2 1 
ATOM   4345 N N   . SER A 1 583 ? 149.456 136.494 143.741 1.00 122.90 ? 584 SER A N   1 
ATOM   4346 C CA  . SER A 1 583 ? 148.682 136.368 144.974 1.00 120.67 ? 584 SER A CA  1 
ATOM   4347 C C   . SER A 1 583 ? 149.582 136.233 146.197 1.00 118.55 ? 584 SER A C   1 
ATOM   4348 O O   . SER A 1 583 ? 149.147 136.493 147.324 1.00 120.93 ? 584 SER A O   1 
ATOM   4349 C CB  . SER A 1 583 ? 147.732 135.176 144.877 1.00 122.03 ? 584 SER A CB  1 
ATOM   4350 O OG  . SER A 1 583 ? 146.771 135.374 143.858 1.00 121.83 ? 584 SER A OG  1 
ATOM   4351 N N   . GLY A 1 584 ? 150.832 135.811 145.998 1.00 119.40 ? 585 GLY A N   1 
ATOM   4352 C CA  . GLY A 1 584 ? 151.791 135.834 147.089 1.00 120.75 ? 585 GLY A CA  1 
ATOM   4353 C C   . GLY A 1 584 ? 152.154 137.244 147.516 1.00 117.96 ? 585 GLY A C   1 
ATOM   4354 O O   . GLY A 1 584 ? 152.376 137.505 148.700 1.00 114.68 ? 585 GLY A O   1 
ATOM   4355 N N   . LEU A 1 585 ? 152.222 138.170 146.557 1.00 123.44 ? 586 LEU A N   1 
ATOM   4356 C CA  . LEU A 1 585 ? 152.568 139.551 146.881 1.00 117.78 ? 586 LEU A CA  1 
ATOM   4357 C C   . LEU A 1 585 ? 151.420 140.276 147.566 1.00 117.83 ? 586 LEU A C   1 
ATOM   4358 O O   . LEU A 1 585 ? 151.648 141.230 148.317 1.00 122.84 ? 586 LEU A O   1 
ATOM   4359 C CB  . LEU A 1 585 ? 152.990 140.305 145.622 1.00 116.41 ? 586 LEU A CB  1 
ATOM   4360 C CG  . LEU A 1 585 ? 154.300 139.872 144.976 1.00 125.53 ? 586 LEU A CG  1 
ATOM   4361 C CD1 . LEU A 1 585 ? 154.510 140.606 143.667 1.00 132.86 ? 586 LEU A CD1 1 
ATOM   4362 C CD2 . LEU A 1 585 ? 155.437 140.164 145.935 1.00 126.40 ? 586 LEU A CD2 1 
ATOM   4363 N N   . PHE A 1 586 ? 150.178 139.854 147.310 1.00 110.03 ? 587 PHE A N   1 
ATOM   4364 C CA  . PHE A 1 586 ? 149.037 140.530 147.922 1.00 112.00 ? 587 PHE A CA  1 
ATOM   4365 C C   . PHE A 1 586 ? 148.983 140.272 149.423 1.00 111.36 ? 587 PHE A C   1 
ATOM   4366 O O   . PHE A 1 586 ? 148.589 141.151 150.198 1.00 114.16 ? 587 PHE A O   1 
ATOM   4367 C CB  . PHE A 1 586 ? 147.737 140.093 147.252 1.00 118.36 ? 587 PHE A CB  1 
ATOM   4368 C CG  . PHE A 1 586 ? 146.571 140.985 147.566 1.00 116.90 ? 587 PHE A CG  1 
ATOM   4369 C CD1 . PHE A 1 586 ? 146.760 142.344 147.766 1.00 109.50 ? 587 PHE A CD1 1 
ATOM   4370 C CD2 . PHE A 1 586 ? 145.289 140.467 147.668 1.00 117.46 ? 587 PHE A CD2 1 
ATOM   4371 C CE1 . PHE A 1 586 ? 145.696 143.168 148.063 1.00 111.99 ? 587 PHE A CE1 1 
ATOM   4372 C CE2 . PHE A 1 586 ? 144.217 141.289 147.961 1.00 116.32 ? 587 PHE A CE2 1 
ATOM   4373 C CZ  . PHE A 1 586 ? 144.422 142.643 148.158 1.00 116.73 ? 587 PHE A CZ  1 
ATOM   4374 N N   . SER A 1 587 ? 149.377 139.073 149.852 1.00 111.58 ? 588 SER A N   1 
ATOM   4375 C CA  . SER A 1 587 ? 149.553 138.827 151.277 1.00 114.84 ? 588 SER A CA  1 
ATOM   4376 C C   . SER A 1 587 ? 150.844 139.448 151.794 1.00 112.39 ? 588 SER A C   1 
ATOM   4377 O O   . SER A 1 587 ? 150.940 139.774 152.982 1.00 117.51 ? 588 SER A O   1 
ATOM   4378 C CB  . SER A 1 587 ? 149.542 137.325 151.554 1.00 122.75 ? 588 SER A CB  1 
ATOM   4379 O OG  . SER A 1 587 ? 148.335 136.735 151.110 1.00 126.52 ? 588 SER A OG  1 
ATOM   4380 N N   . ALA A 1 588 ? 151.846 139.604 150.924 1.00 110.76 ? 589 ALA A N   1 
ATOM   4381 C CA  . ALA A 1 588 ? 153.144 140.113 151.357 1.00 108.27 ? 589 ALA A CA  1 
ATOM   4382 C C   . ALA A 1 588 ? 153.094 141.609 151.646 1.00 106.54 ? 589 ALA A C   1 
ATOM   4383 O O   . ALA A 1 588 ? 153.596 142.067 152.678 1.00 113.35 ? 589 ALA A O   1 
ATOM   4384 C CB  . ALA A 1 588 ? 154.205 139.806 150.301 1.00 117.61 ? 589 ALA A CB  1 
ATOM   4385 N N   . MET A 1 589 ? 152.494 142.392 150.746 1.00 106.09 ? 590 MET A N   1 
ATOM   4386 C CA  . MET A 1 589 ? 152.457 143.835 150.963 1.00 109.79 ? 590 MET A CA  1 
ATOM   4387 C C   . MET A 1 589 ? 151.360 144.230 151.942 1.00 113.67 ? 590 MET A C   1 
ATOM   4388 O O   . MET A 1 589 ? 151.352 145.361 152.439 1.00 116.24 ? 590 MET A O   1 
ATOM   4389 C CB  . MET A 1 589 ? 152.297 144.574 149.634 1.00 112.49 ? 590 MET A CB  1 
ATOM   4390 C CG  . MET A 1 589 ? 153.220 144.057 148.546 1.00 123.19 ? 590 MET A CG  1 
ATOM   4391 S SD  . MET A 1 589 ? 154.937 144.552 148.785 1.00 151.19 ? 590 MET A SD  1 
ATOM   4392 C CE  . MET A 1 589 ? 155.701 143.837 147.331 1.00 131.54 ? 590 MET A CE  1 
ATOM   4393 N N   . TRP A 1 590 ? 150.367 143.296 152.275 1.00 112.28 ? 591 TRP A N   1 
ATOM   4394 C CA  . TRP A 1 590 ? 149.477 143.483 153.414 1.00 108.67 ? 591 TRP A CA  1 
ATOM   4395 C C   . TRP A 1 590 ? 150.213 143.227 154.724 1.00 106.26 ? 591 TRP A C   1 
ATOM   4396 O O   . TRP A 1 590 ? 149.850 143.776 155.770 1.00 110.07 ? 591 TRP A O   1 
ATOM   4397 C CB  . TRP A 1 590 ? 148.264 142.561 153.271 1.00 118.14 ? 591 TRP A CB  1 
ATOM   4398 C CG  . TRP A 1 590 ? 147.038 142.982 154.035 1.00 126.13 ? 591 TRP A CG  1 
ATOM   4399 C CD1 . TRP A 1 590 ? 146.993 143.719 155.179 1.00 125.90 ? 591 TRP A CD1 1 
ATOM   4400 C CD2 . TRP A 1 590 ? 145.677 142.686 153.698 1.00 130.11 ? 591 TRP A CD2 1 
ATOM   4401 N NE1 . TRP A 1 590 ? 145.693 143.899 155.579 1.00 130.95 ? 591 TRP A NE1 1 
ATOM   4402 C CE2 . TRP A 1 590 ? 144.865 143.273 154.685 1.00 136.99 ? 591 TRP A CE2 1 
ATOM   4403 C CE3 . TRP A 1 590 ? 145.069 141.978 152.657 1.00 130.67 ? 591 TRP A CE3 1 
ATOM   4404 C CZ2 . TRP A 1 590 ? 143.475 143.178 154.664 1.00 139.03 ? 591 TRP A CZ2 1 
ATOM   4405 C CZ3 . TRP A 1 590 ? 143.688 141.883 152.637 1.00 137.45 ? 591 TRP A CZ3 1 
ATOM   4406 C CH2 . TRP A 1 590 ? 142.907 142.480 153.634 1.00 136.48 ? 591 TRP A CH2 1 
ATOM   4407 N N   . SER A 1 591 ? 151.284 142.527 154.682 1.00 110.29 ? 592 SER A N   1 
ATOM   4408 C CA  . SER A 1 591 ? 152.021 142.257 155.911 1.00 104.63 ? 592 SER A CA  1 
ATOM   4409 C C   . SER A 1 591 ? 153.044 143.335 156.243 1.00 110.11 ? 592 SER A C   1 
ATOM   4410 O O   . SER A 1 591 ? 153.359 143.530 157.422 1.00 113.69 ? 592 SER A O   1 
ATOM   4411 C CB  . SER A 1 591 ? 152.727 140.908 155.817 1.00 106.40 ? 592 SER A CB  1 
ATOM   4412 O OG  . SER A 1 591 ? 153.072 140.447 157.108 1.00 113.75 ? 592 SER A OG  1 
ATOM   4413 N N   . ILE A 1 592 ? 153.589 144.028 155.241 1.00 110.20 ? 593 ILE A N   1 
ATOM   4414 C CA  . ILE A 1 592 ? 154.573 145.063 155.544 1.00 114.87 ? 593 ILE A CA  1 
ATOM   4415 C C   . ILE A 1 592 ? 153.888 146.315 156.074 1.00 118.66 ? 593 ILE A C   1 
ATOM   4416 O O   . ILE A 1 592 ? 154.510 147.120 156.777 1.00 122.86 ? 593 ILE A O   1 
ATOM   4417 C CB  . ILE A 1 592 ? 155.454 145.367 154.317 1.00 117.53 ? 593 ILE A CB  1 
ATOM   4418 C CG1 . ILE A 1 592 ? 154.624 145.906 153.153 1.00 118.22 ? 593 ILE A CG1 1 
ATOM   4419 C CG2 . ILE A 1 592 ? 156.218 144.126 153.891 1.00 117.94 ? 593 ILE A CG2 1 
ATOM   4420 C CD1 . ILE A 1 592 ? 155.460 146.426 152.005 1.00 123.22 ? 593 ILE A CD1 1 
ATOM   4421 N N   . GLY A 1 593 ? 152.609 146.507 155.747 1.00 113.50 ? 594 GLY A N   1 
ATOM   4422 C CA  . GLY A 1 593 ? 151.845 147.563 156.387 1.00 115.28 ? 594 GLY A CA  1 
ATOM   4423 C C   . GLY A 1 593 ? 151.577 147.273 157.851 1.00 116.04 ? 594 GLY A C   1 
ATOM   4424 O O   . GLY A 1 593 ? 151.561 148.184 158.682 1.00 121.93 ? 594 GLY A O   1 
ATOM   4425 N N   . ALA A 1 594 ? 151.367 145.999 158.187 1.00 115.61 ? 595 ALA A N   1 
ATOM   4426 C CA  . ALA A 1 594 ? 151.086 145.621 159.566 1.00 119.41 ? 595 ALA A CA  1 
ATOM   4427 C C   . ALA A 1 594 ? 152.339 145.580 160.432 1.00 117.84 ? 595 ALA A C   1 
ATOM   4428 O O   . ALA A 1 594 ? 152.227 145.420 161.652 1.00 116.66 ? 595 ALA A O   1 
ATOM   4429 C CB  . ALA A 1 594 ? 150.383 144.264 159.604 1.00 115.22 ? 595 ALA A CB  1 
ATOM   4430 N N   . PHE A 1 595 ? 153.526 145.700 159.838 1.00 119.10 ? 596 PHE A N   1 
ATOM   4431 C CA  . PHE A 1 595 ? 154.746 145.757 160.636 1.00 127.02 ? 596 PHE A CA  1 
ATOM   4432 C C   . PHE A 1 595 ? 155.065 147.197 161.021 1.00 132.57 ? 596 PHE A C   1 
ATOM   4433 O O   . PHE A 1 595 ? 155.161 147.527 162.207 1.00 135.14 ? 596 PHE A O   1 
ATOM   4434 C CB  . PHE A 1 595 ? 155.912 145.126 159.867 1.00 129.85 ? 596 PHE A CB  1 
ATOM   4435 C CG  . PHE A 1 595 ? 157.241 145.204 160.583 1.00 138.78 ? 596 PHE A CG  1 
ATOM   4436 C CD1 . PHE A 1 595 ? 157.341 144.930 161.943 1.00 137.76 ? 596 PHE A CD1 1 
ATOM   4437 C CD2 . PHE A 1 595 ? 158.390 145.553 159.890 1.00 141.25 ? 596 PHE A CD2 1 
ATOM   4438 C CE1 . PHE A 1 595 ? 158.558 145.002 162.593 1.00 136.30 ? 596 PHE A CE1 1 
ATOM   4439 C CE2 . PHE A 1 595 ? 159.612 145.627 160.535 1.00 137.84 ? 596 PHE A CE2 1 
ATOM   4440 C CZ  . PHE A 1 595 ? 159.695 145.351 161.889 1.00 134.12 ? 596 PHE A CZ  1 
ATOM   4441 N N   . MET A 1 596 ? 155.226 148.073 160.029 1.00 132.27 ? 597 MET A N   1 
ATOM   4442 C CA  . MET A 1 596 ? 155.592 149.454 160.321 1.00 131.62 ? 597 MET A CA  1 
ATOM   4443 C C   . MET A 1 596 ? 154.393 150.305 160.722 1.00 127.73 ? 597 MET A C   1 
ATOM   4444 O O   . MET A 1 596 ? 154.575 151.465 161.101 1.00 129.33 ? 597 MET A O   1 
ATOM   4445 C CB  . MET A 1 596 ? 156.337 150.057 159.121 1.00 132.08 ? 597 MET A CB  1 
ATOM   4446 C CG  . MET A 1 596 ? 155.579 150.112 157.786 1.00 132.48 ? 597 MET A CG  1 
ATOM   4447 S SD  . MET A 1 596 ? 154.419 151.474 157.532 1.00 142.67 ? 597 MET A SD  1 
ATOM   4448 C CE  . MET A 1 596 ? 155.556 152.848 157.361 1.00 137.09 ? 597 MET A CE  1 
ATOM   4449 N N   . GLY A 1 597 ? 153.181 149.768 160.636 1.00 127.76 ? 598 GLY A N   1 
ATOM   4450 C CA  . GLY A 1 597 ? 152.002 150.488 161.052 1.00 129.78 ? 598 GLY A CA  1 
ATOM   4451 C C   . GLY A 1 597 ? 151.871 150.623 162.557 1.00 136.53 ? 598 GLY A C   1 
ATOM   4452 O O   . GLY A 1 597 ? 151.997 151.718 163.113 1.00 144.83 ? 598 GLY A O   1 
ATOM   4453 N N   . PRO A 1 598 ? 151.594 149.511 163.248 1.00 130.94 ? 599 PRO A N   1 
ATOM   4454 C CA  . PRO A 1 598 ? 151.414 149.591 164.709 1.00 136.70 ? 599 PRO A CA  1 
ATOM   4455 C C   . PRO A 1 598 ? 152.694 149.848 165.489 1.00 142.69 ? 599 PRO A C   1 
ATOM   4456 O O   . PRO A 1 598 ? 152.646 150.530 166.522 1.00 147.58 ? 599 PRO A O   1 
ATOM   4457 C CB  . PRO A 1 598 ? 150.815 148.222 165.057 1.00 129.69 ? 599 PRO A CB  1 
ATOM   4458 C CG  . PRO A 1 598 ? 150.132 147.790 163.820 1.00 127.30 ? 599 PRO A CG  1 
ATOM   4459 C CD  . PRO A 1 598 ? 150.989 148.287 162.694 1.00 125.18 ? 599 PRO A CD  1 
ATOM   4460 N N   . THR A 1 599 ? 153.834 149.312 165.041 1.00 136.98 ? 600 THR A N   1 
ATOM   4461 C CA  . THR A 1 599 ? 155.067 149.432 165.816 1.00 140.59 ? 600 THR A CA  1 
ATOM   4462 C C   . THR A 1 599 ? 155.602 150.859 165.794 1.00 144.46 ? 600 THR A C   1 
ATOM   4463 O O   . THR A 1 599 ? 156.010 151.396 166.830 1.00 148.81 ? 600 THR A O   1 
ATOM   4464 C CB  . THR A 1 599 ? 156.119 148.454 165.296 1.00 148.34 ? 600 THR A CB  1 
ATOM   4465 O OG1 . THR A 1 599 ? 156.403 148.740 163.921 1.00 142.98 ? 600 THR A OG1 1 
ATOM   4466 C CG2 . THR A 1 599 ? 155.632 147.017 165.439 1.00 148.81 ? 600 THR A CG2 1 
ATOM   4467 N N   . LEU A 1 600 ? 155.606 151.492 164.619 1.00 145.72 ? 601 LEU A N   1 
ATOM   4468 C CA  . LEU A 1 600 ? 155.920 152.916 164.568 1.00 146.89 ? 601 LEU A CA  1 
ATOM   4469 C C   . LEU A 1 600 ? 154.746 153.758 165.047 1.00 143.24 ? 601 LEU A C   1 
ATOM   4470 O O   . LEU A 1 600 ? 154.928 154.929 165.395 1.00 142.70 ? 601 LEU A O   1 
ATOM   4471 C CB  . LEU A 1 600 ? 156.324 153.328 163.152 1.00 144.02 ? 601 LEU A CB  1 
ATOM   4472 C CG  . LEU A 1 600 ? 157.481 152.579 162.487 1.00 135.93 ? 601 LEU A CG  1 
ATOM   4473 C CD1 . LEU A 1 600 ? 157.892 153.279 161.201 1.00 126.25 ? 601 LEU A CD1 1 
ATOM   4474 C CD2 . LEU A 1 600 ? 158.670 152.459 163.429 1.00 137.61 ? 601 LEU A CD2 1 
ATOM   4475 N N   . GLY A 1 601 ? 153.541 153.182 165.059 1.00 140.28 ? 602 GLY A N   1 
ATOM   4476 C CA  . GLY A 1 601 ? 152.394 153.889 165.604 1.00 144.40 ? 602 GLY A CA  1 
ATOM   4477 C C   . GLY A 1 601 ? 152.505 154.103 167.100 1.00 157.92 ? 602 GLY A C   1 
ATOM   4478 O O   . GLY A 1 601 ? 152.114 155.150 167.621 1.00 162.54 ? 602 GLY A O   1 
ATOM   4479 N N   . GLY A 1 602 ? 153.040 153.110 167.812 1.00 159.58 ? 603 GLY A N   1 
ATOM   4480 C CA  . GLY A 1 602 ? 153.333 153.304 169.222 1.00 163.42 ? 603 GLY A CA  1 
ATOM   4481 C C   . GLY A 1 602 ? 154.522 154.220 169.444 1.00 164.58 ? 603 GLY A C   1 
ATOM   4482 O O   . GLY A 1 602 ? 154.646 154.846 170.500 1.00 166.53 ? 603 GLY A O   1 
ATOM   4483 N N   . PHE A 1 603 ? 155.402 154.334 168.401 1.00 160.24 ? 604 PHE A N   1 
ATOM   4484 C CA  . PHE A 1 603 ? 156.501 155.294 168.452 1.00 157.98 ? 604 PHE A CA  1 
ATOM   4485 C C   . PHE A 1 603 ? 156.000 156.724 168.304 1.00 158.42 ? 604 PHE A C   1 
ATOM   4486 O O   . PHE A 1 603 ? 156.432 157.621 169.036 1.00 157.69 ? 604 PHE A O   1 
ATOM   4487 C CB  . PHE A 1 603 ? 157.526 154.973 167.364 1.00 156.13 ? 604 PHE A CB  1 
ATOM   4488 C CG  . PHE A 1 603 ? 158.950 154.992 167.844 1.00 160.77 ? 604 PHE A CG  1 
ATOM   4489 C CD1 . PHE A 1 603 ? 159.454 153.954 168.609 1.00 161.13 ? 604 PHE A CD1 1 
ATOM   4490 C CD2 . PHE A 1 603 ? 159.786 156.051 167.527 1.00 162.26 ? 604 PHE A CD2 1 
ATOM   4491 C CE1 . PHE A 1 603 ? 160.765 153.972 169.049 1.00 161.36 ? 604 PHE A CE1 1 
ATOM   4492 C CE2 . PHE A 1 603 ? 161.097 156.074 167.964 1.00 162.89 ? 604 PHE A CE2 1 
ATOM   4493 C CZ  . PHE A 1 603 ? 161.586 155.034 168.726 1.00 162.34 ? 604 PHE A CZ  1 
ATOM   4494 N N   . LEU A 1 604 ? 155.195 156.893 167.354 1.00 159.00 ? 605 LEU A N   1 
ATOM   4495 C CA  . LEU A 1 604 ? 154.721 158.242 167.065 1.00 163.05 ? 605 LEU A CA  1 
ATOM   4496 C C   . LEU A 1 604 ? 153.635 158.693 168.033 1.00 162.59 ? 605 LEU A C   1 
ATOM   4497 O O   . LEU A 1 604 ? 153.350 159.892 168.118 1.00 164.71 ? 605 LEU A O   1 
ATOM   4498 C CB  . LEU A 1 604 ? 154.215 158.320 165.624 1.00 162.33 ? 605 LEU A CB  1 
ATOM   4499 C CG  . LEU A 1 604 ? 155.293 158.125 164.554 1.00 162.88 ? 605 LEU A CG  1 
ATOM   4500 C CD1 . LEU A 1 604 ? 154.675 157.923 163.179 1.00 156.00 ? 605 LEU A CD1 1 
ATOM   4501 C CD2 . LEU A 1 604 ? 156.262 159.299 164.548 1.00 158.12 ? 605 LEU A CD2 1 
ATOM   4502 N N   . TYR A 1 605 ? 153.018 157.760 168.763 1.00 160.00 ? 606 TYR A N   1 
ATOM   4503 C CA  . TYR A 1 605 ? 152.076 158.147 169.809 1.00 168.68 ? 606 TYR A CA  1 
ATOM   4504 C C   . TYR A 1 605 ? 152.808 158.752 170.999 1.00 171.76 ? 606 TYR A C   1 
ATOM   4505 O O   . TYR A 1 605 ? 152.251 159.583 171.728 1.00 170.01 ? 606 TYR A O   1 
ATOM   4506 C CB  . TYR A 1 605 ? 151.250 156.938 170.247 1.00 171.36 ? 606 TYR A CB  1 
ATOM   4507 C CG  . TYR A 1 605 ? 149.933 157.288 170.902 1.00 168.46 ? 606 TYR A CG  1 
ATOM   4508 C CD1 . TYR A 1 605 ? 148.781 157.459 170.142 1.00 161.42 ? 606 TYR A CD1 1 
ATOM   4509 C CD2 . TYR A 1 605 ? 149.842 157.452 172.279 1.00 165.89 ? 606 TYR A CD2 1 
ATOM   4510 C CE1 . TYR A 1 605 ? 147.576 157.779 170.735 1.00 163.17 ? 606 TYR A CE1 1 
ATOM   4511 C CE2 . TYR A 1 605 ? 148.642 157.774 172.881 1.00 167.97 ? 606 TYR A CE2 1 
ATOM   4512 C CZ  . TYR A 1 605 ? 147.513 157.935 172.105 1.00 172.28 ? 606 TYR A CZ  1 
ATOM   4513 O OH  . TYR A 1 605 ? 146.315 158.255 172.702 1.00 181.26 ? 606 TYR A OH  1 
ATOM   4514 N N   . GLU A 1 606 ? 154.060 158.338 171.211 1.00 171.76 ? 607 GLU A N   1 
ATOM   4515 C CA  . GLU A 1 606 ? 154.862 158.859 172.313 1.00 170.93 ? 607 GLU A CA  1 
ATOM   4516 C C   . GLU A 1 606 ? 155.281 160.304 172.059 1.00 172.78 ? 607 GLU A C   1 
ATOM   4517 O O   . GLU A 1 606 ? 155.515 161.065 173.006 1.00 173.61 ? 607 GLU A O   1 
ATOM   4518 C CB  . GLU A 1 606 ? 156.080 157.948 172.517 1.00 169.03 ? 607 GLU A CB  1 
ATOM   4519 C CG  . GLU A 1 606 ? 156.931 158.181 173.770 1.00 176.35 ? 607 GLU A CG  1 
ATOM   4520 C CD  . GLU A 1 606 ? 157.995 159.252 173.590 1.00 175.03 ? 607 GLU A CD  1 
ATOM   4521 O OE1 . GLU A 1 606 ? 158.460 159.440 172.446 1.00 165.26 ? 607 GLU A OE1 1 
ATOM   4522 O OE2 . GLU A 1 606 ? 158.366 159.900 174.590 1.00 179.14 ? 607 GLU A OE2 1 
ATOM   4523 N N   . LYS A 1 607 ? 155.362 160.705 170.786 1.00 171.68 ? 608 LYS A N   1 
ATOM   4524 C CA  . LYS A 1 607 ? 155.965 161.988 170.436 1.00 168.71 ? 608 LYS A CA  1 
ATOM   4525 C C   . LYS A 1 607 ? 155.059 163.158 170.807 1.00 165.73 ? 608 LYS A C   1 
ATOM   4526 O O   . LYS A 1 607 ? 155.406 163.984 171.658 1.00 167.77 ? 608 LYS A O   1 
ATOM   4527 C CB  . LYS A 1 607 ? 156.293 162.014 168.942 1.00 164.45 ? 608 LYS A CB  1 
ATOM   4528 C CG  . LYS A 1 607 ? 157.739 161.677 168.616 1.00 165.00 ? 608 LYS A CG  1 
ATOM   4529 C CD  . LYS A 1 607 ? 158.696 162.672 169.252 1.00 164.54 ? 608 LYS A CD  1 
ATOM   4530 C CE  . LYS A 1 607 ? 160.143 162.297 168.978 1.00 158.30 ? 608 LYS A CE  1 
ATOM   4531 N NZ  . LYS A 1 607 ? 161.095 163.166 169.724 1.00 146.51 ? 608 LYS A NZ  1 
ATOM   4532 N N   . ILE A 1 608 ? 153.888 163.246 170.177 1.00 162.35 ? 609 ILE A N   1 
ATOM   4533 C CA  . ILE A 1 608 ? 152.992 164.376 170.404 1.00 164.33 ? 609 ILE A CA  1 
ATOM   4534 C C   . ILE A 1 608 ? 151.646 163.879 170.910 1.00 169.55 ? 609 ILE A C   1 
ATOM   4535 O O   . ILE A 1 608 ? 151.219 164.225 172.018 1.00 170.17 ? 609 ILE A O   1 
ATOM   4536 C CB  . ILE A 1 608 ? 152.814 165.220 169.128 1.00 157.32 ? 609 ILE A CB  1 
ATOM   4537 C CG1 . ILE A 1 608 ? 154.162 165.744 168.631 1.00 152.36 ? 609 ILE A CG1 1 
ATOM   4538 C CG2 . ILE A 1 608 ? 151.857 166.373 169.382 1.00 157.36 ? 609 ILE A CG2 1 
ATOM   4539 C CD1 . ILE A 1 608 ? 154.838 166.692 169.596 1.00 152.50 ? 609 ILE A CD1 1 
ATOM   4540 N N   . GLY A 1 609 ? 150.972 163.072 170.108 1.00 167.62 ? 610 GLY A N   1 
ATOM   4541 C CA  . GLY A 1 609 ? 149.659 162.571 170.431 1.00 160.98 ? 610 GLY A CA  1 
ATOM   4542 C C   . GLY A 1 609 ? 148.820 162.458 169.180 1.00 156.31 ? 610 GLY A C   1 
ATOM   4543 O O   . GLY A 1 609 ? 149.286 162.720 168.073 1.00 152.19 ? 610 GLY A O   1 
ATOM   4544 N N   . PHE A 1 610 ? 147.549 162.095 169.380 1.00 159.95 ? 611 PHE A N   1 
ATOM   4545 C CA  . PHE A 1 610 ? 146.651 161.747 168.282 1.00 155.86 ? 611 PHE A CA  1 
ATOM   4546 C C   . PHE A 1 610 ? 146.267 162.942 167.417 1.00 152.64 ? 611 PHE A C   1 
ATOM   4547 O O   . PHE A 1 610 ? 145.785 162.744 166.297 1.00 153.08 ? 611 PHE A O   1 
ATOM   4548 C CB  . PHE A 1 610 ? 145.393 161.084 168.843 1.00 155.97 ? 611 PHE A CB  1 
ATOM   4549 C CG  . PHE A 1 610 ? 144.686 160.188 167.868 1.00 159.35 ? 611 PHE A CG  1 
ATOM   4550 C CD1 . PHE A 1 610 ? 145.123 158.890 167.658 1.00 166.18 ? 611 PHE A CD1 1 
ATOM   4551 C CD2 . PHE A 1 610 ? 143.568 160.636 167.178 1.00 161.22 ? 611 PHE A CD2 1 
ATOM   4552 C CE1 . PHE A 1 610 ? 144.469 158.058 166.764 1.00 167.04 ? 611 PHE A CE1 1 
ATOM   4553 C CE2 . PHE A 1 610 ? 142.910 159.811 166.281 1.00 162.61 ? 611 PHE A CE2 1 
ATOM   4554 C CZ  . PHE A 1 610 ? 143.361 158.520 166.075 1.00 166.00 ? 611 PHE A CZ  1 
ATOM   4555 N N   . GLU A 1 611 ? 146.469 164.169 167.901 1.00 154.55 ? 612 GLU A N   1 
ATOM   4556 C CA  . GLU A 1 611 ? 146.152 165.344 167.093 1.00 158.72 ? 612 GLU A CA  1 
ATOM   4557 C C   . GLU A 1 611 ? 147.137 165.511 165.939 1.00 158.45 ? 612 GLU A C   1 
ATOM   4558 O O   . GLU A 1 611 ? 146.800 166.112 164.913 1.00 161.03 ? 612 GLU A O   1 
ATOM   4559 C CB  . GLU A 1 611 ? 146.112 166.596 167.978 1.00 162.72 ? 612 GLU A CB  1 
ATOM   4560 C CG  . GLU A 1 611 ? 147.452 167.039 168.569 1.00 158.73 ? 612 GLU A CG  1 
ATOM   4561 C CD  . GLU A 1 611 ? 147.806 166.336 169.874 1.00 156.95 ? 612 GLU A CD  1 
ATOM   4562 O OE1 . GLU A 1 611 ? 147.191 165.298 170.198 1.00 154.56 ? 612 GLU A OE1 1 
ATOM   4563 O OE2 . GLU A 1 611 ? 148.707 166.830 170.582 1.00 163.74 ? 612 GLU A OE2 1 
ATOM   4564 N N   . TRP A 1 612 ? 148.353 164.981 166.081 1.00 154.64 ? 613 TRP A N   1 
ATOM   4565 C CA  . TRP A 1 612 ? 149.308 164.961 164.984 1.00 146.01 ? 613 TRP A CA  1 
ATOM   4566 C C   . TRP A 1 612 ? 149.599 163.564 164.459 1.00 138.68 ? 613 TRP A C   1 
ATOM   4567 O O   . TRP A 1 612 ? 150.015 163.438 163.304 1.00 134.86 ? 613 TRP A O   1 
ATOM   4568 C CB  . TRP A 1 612 ? 150.632 165.611 165.403 1.00 145.91 ? 613 TRP A CB  1 
ATOM   4569 C CG  . TRP A 1 612 ? 150.620 167.103 165.354 1.00 143.55 ? 613 TRP A CG  1 
ATOM   4570 C CD1 . TRP A 1 612 ? 149.539 167.910 165.153 1.00 147.74 ? 613 TRP A CD1 1 
ATOM   4571 C CD2 . TRP A 1 612 ? 151.750 167.971 165.488 1.00 138.50 ? 613 TRP A CD2 1 
ATOM   4572 N NE1 . TRP A 1 612 ? 149.925 169.228 165.166 1.00 148.62 ? 613 TRP A NE1 1 
ATOM   4573 C CE2 . TRP A 1 612 ? 151.279 169.292 165.368 1.00 147.11 ? 613 TRP A CE2 1 
ATOM   4574 C CE3 . TRP A 1 612 ? 153.115 167.758 165.703 1.00 133.24 ? 613 TRP A CE3 1 
ATOM   4575 C CZ2 . TRP A 1 612 ? 152.124 170.397 165.457 1.00 144.45 ? 613 TRP A CZ2 1 
ATOM   4576 C CZ3 . TRP A 1 612 ? 153.952 168.856 165.790 1.00 129.42 ? 613 TRP A CZ3 1 
ATOM   4577 C CH2 . TRP A 1 612 ? 153.454 170.157 165.668 1.00 131.28 ? 613 TRP A CH2 1 
ATOM   4578 N N   . ALA A 1 613 ? 149.379 162.517 165.264 1.00 140.16 ? 614 ALA A N   1 
ATOM   4579 C CA  . ALA A 1 613 ? 149.700 161.159 164.833 1.00 137.47 ? 614 ALA A CA  1 
ATOM   4580 C C   . ALA A 1 613 ? 148.740 160.638 163.773 1.00 134.63 ? 614 ALA A C   1 
ATOM   4581 O O   . ALA A 1 613 ? 149.049 159.642 163.112 1.00 132.59 ? 614 ALA A O   1 
ATOM   4582 C CB  . ALA A 1 613 ? 149.710 160.203 166.026 1.00 144.36 ? 614 ALA A CB  1 
ATOM   4583 N N   . ALA A 1 614 ? 147.583 161.273 163.605 1.00 139.96 ? 615 ALA A N   1 
ATOM   4584 C CA  . ALA A 1 614 ? 146.725 160.983 162.467 1.00 140.70 ? 615 ALA A CA  1 
ATOM   4585 C C   . ALA A 1 614 ? 147.085 161.823 161.251 1.00 134.62 ? 615 ALA A C   1 
ATOM   4586 O O   . ALA A 1 614 ? 146.891 161.374 160.116 1.00 135.54 ? 615 ALA A O   1 
ATOM   4587 C CB  . ALA A 1 614 ? 145.257 161.212 162.837 1.00 142.91 ? 615 ALA A CB  1 
ATOM   4588 N N   . ALA A 1 615 ? 147.615 163.027 161.467 1.00 132.17 ? 616 ALA A N   1 
ATOM   4589 C CA  . ALA A 1 615 ? 148.009 163.891 160.360 1.00 133.21 ? 616 ALA A CA  1 
ATOM   4590 C C   . ALA A 1 615 ? 149.273 163.384 159.675 1.00 131.26 ? 616 ALA A C   1 
ATOM   4591 O O   . ALA A 1 615 ? 149.352 163.369 158.442 1.00 131.78 ? 616 ALA A O   1 
ATOM   4592 C CB  . ALA A 1 615 ? 148.209 165.323 160.858 1.00 140.11 ? 616 ALA A CB  1 
ATOM   4593 N N   . ILE A 1 616 ? 150.274 162.968 160.456 1.00 129.35 ? 617 ILE A N   1 
ATOM   4594 C CA  . ILE A 1 616 ? 151.516 162.492 159.859 1.00 123.09 ? 617 ILE A CA  1 
ATOM   4595 C C   . ILE A 1 616 ? 151.366 161.081 159.317 1.00 121.44 ? 617 ILE A C   1 
ATOM   4596 O O   . ILE A 1 616 ? 152.204 160.626 158.532 1.00 121.21 ? 617 ILE A O   1 
ATOM   4597 C CB  . ILE A 1 616 ? 152.684 162.561 160.861 1.00 124.85 ? 617 ILE A CB  1 
ATOM   4598 C CG1 . ILE A 1 616 ? 152.428 161.651 162.061 1.00 131.57 ? 617 ILE A CG1 1 
ATOM   4599 C CG2 . ILE A 1 616 ? 152.908 163.994 161.316 1.00 131.46 ? 617 ILE A CG2 1 
ATOM   4600 C CD1 . ILE A 1 616 ? 153.619 161.511 162.973 1.00 135.39 ? 617 ILE A CD1 1 
ATOM   4601 N N   . GLN A 1 617 ? 150.315 160.371 159.722 1.00 123.02 ? 618 GLN A N   1 
ATOM   4602 C CA  . GLN A 1 617 ? 150.052 159.054 159.162 1.00 126.08 ? 618 GLN A CA  1 
ATOM   4603 C C   . GLN A 1 617 ? 149.453 159.176 157.767 1.00 124.03 ? 618 GLN A C   1 
ATOM   4604 O O   . GLN A 1 617 ? 149.693 158.328 156.900 1.00 125.85 ? 618 GLN A O   1 
ATOM   4605 C CB  . GLN A 1 617 ? 149.122 158.278 160.100 1.00 131.95 ? 618 GLN A CB  1 
ATOM   4606 C CG  . GLN A 1 617 ? 148.710 156.861 159.683 1.00 128.55 ? 618 GLN A CG  1 
ATOM   4607 C CD  . GLN A 1 617 ? 149.797 155.800 159.889 1.00 132.99 ? 618 GLN A CD  1 
ATOM   4608 O OE1 . GLN A 1 617 ? 149.529 154.606 160.027 1.00 136.24 ? 618 GLN A OE1 1 
ATOM   4609 N NE2 . GLN A 1 617 ? 151.041 156.245 159.872 1.00 131.57 ? 618 GLN A NE2 1 
ATOM   4610 N N   . GLY A 1 618 ? 148.688 160.238 157.531 1.00 122.08 ? 619 GLY A N   1 
ATOM   4611 C CA  . GLY A 1 618 ? 148.041 160.454 156.255 1.00 119.91 ? 619 GLY A CA  1 
ATOM   4612 C C   . GLY A 1 618 ? 148.908 161.122 155.208 1.00 118.15 ? 619 GLY A C   1 
ATOM   4613 O O   . GLY A 1 618 ? 148.602 161.038 154.016 1.00 122.96 ? 619 GLY A O   1 
ATOM   4614 N N   . LEU A 1 619 ? 149.986 161.794 155.623 1.00 112.98 ? 620 LEU A N   1 
ATOM   4615 C CA  . LEU A 1 619 ? 150.874 162.393 154.631 1.00 115.38 ? 620 LEU A CA  1 
ATOM   4616 C C   . LEU A 1 619 ? 151.763 161.345 153.976 1.00 119.33 ? 620 LEU A C   1 
ATOM   4617 O O   . LEU A 1 619 ? 152.272 161.570 152.872 1.00 122.22 ? 620 LEU A O   1 
ATOM   4618 C CB  . LEU A 1 619 ? 151.699 163.528 155.252 1.00 121.41 ? 620 LEU A CB  1 
ATOM   4619 C CG  . LEU A 1 619 ? 152.707 163.405 156.402 1.00 123.84 ? 620 LEU A CG  1 
ATOM   4620 C CD1 . LEU A 1 619 ? 154.102 162.992 155.946 1.00 118.87 ? 620 LEU A CD1 1 
ATOM   4621 C CD2 . LEU A 1 619 ? 152.779 164.731 157.144 1.00 125.74 ? 620 LEU A CD2 1 
ATOM   4622 N N   . TRP A 1 620 ? 151.849 160.366 154.571 1.00 115.73 ? 621 TRP A N   1 
ATOM   4623 C CA  . TRP A 1 620 ? 152.468 159.231 153.900 1.00 119.01 ? 621 TRP A CA  1 
ATOM   4624 C C   . TRP A 1 620 ? 151.483 158.555 152.956 1.00 121.86 ? 621 TRP A C   1 
ATOM   4625 O O   . TRP A 1 620 ? 151.882 157.963 151.946 1.00 120.68 ? 621 TRP A O   1 
ATOM   4626 C CB  . TRP A 1 620 ? 153.006 158.247 154.936 1.00 124.20 ? 621 TRP A CB  1 
ATOM   4627 C CG  . TRP A 1 620 ? 154.333 157.675 154.573 1.00 134.49 ? 621 TRP A CG  1 
ATOM   4628 C CD1 . TRP A 1 620 ? 154.936 157.715 153.350 1.00 134.21 ? 621 TRP A CD1 1 
ATOM   4629 C CD2 . TRP A 1 620 ? 155.249 157.013 155.450 1.00 137.03 ? 621 TRP A CD2 1 
ATOM   4630 N NE1 . TRP A 1 620 ? 156.160 157.095 153.405 1.00 136.69 ? 621 TRP A NE1 1 
ATOM   4631 C CE2 . TRP A 1 620 ? 156.377 156.658 154.685 1.00 139.02 ? 621 TRP A CE2 1 
ATOM   4632 C CE3 . TRP A 1 620 ? 155.221 156.677 156.805 1.00 137.03 ? 621 TRP A CE3 1 
ATOM   4633 C CZ2 . TRP A 1 620 ? 157.466 155.985 155.231 1.00 139.81 ? 621 TRP A CZ2 1 
ATOM   4634 C CZ3 . TRP A 1 620 ? 156.304 156.013 157.345 1.00 138.42 ? 621 TRP A CZ3 1 
ATOM   4635 C CH2 . TRP A 1 620 ? 157.410 155.670 156.559 1.00 137.38 ? 621 TRP A CH2 1 
ATOM   4636 N N   . ALA A 1 621 ? 150.275 158.581 153.229 1.00 121.73 ? 622 ALA A N   1 
ATOM   4637 C CA  . ALA A 1 621 ? 149.266 158.184 152.256 1.00 115.50 ? 622 ALA A CA  1 
ATOM   4638 C C   . ALA A 1 621 ? 149.007 159.281 151.233 1.00 118.88 ? 622 ALA A C   1 
ATOM   4639 O O   . ALA A 1 621 ? 148.525 158.993 150.132 1.00 121.79 ? 622 ALA A O   1 
ATOM   4640 C CB  . ALA A 1 621 ? 147.964 157.812 152.965 1.00 113.98 ? 622 ALA A CB  1 
ATOM   4641 N N   . LEU A 1 622 ? 149.305 160.535 151.579 1.00 122.12 ? 623 LEU A N   1 
ATOM   4642 C CA  . LEU A 1 622 ? 149.186 161.619 150.609 1.00 122.32 ? 623 LEU A CA  1 
ATOM   4643 C C   . LEU A 1 622 ? 150.278 161.531 149.553 1.00 122.23 ? 623 LEU A C   1 
ATOM   4644 O O   . LEU A 1 622 ? 150.027 161.776 148.368 1.00 123.57 ? 623 LEU A O   1 
ATOM   4645 C CB  . LEU A 1 622 ? 149.233 162.971 151.322 1.00 125.55 ? 623 LEU A CB  1 
ATOM   4646 C CG  . LEU A 1 622 ? 149.054 164.227 150.466 1.00 131.45 ? 623 LEU A CG  1 
ATOM   4647 C CD1 . LEU A 1 622 ? 147.678 164.248 149.818 1.00 135.96 ? 623 LEU A CD1 1 
ATOM   4648 C CD2 . LEU A 1 622 ? 149.278 165.480 151.298 1.00 129.50 ? 623 LEU A CD2 1 
ATOM   4649 N N   . ILE A 1 623 ? 151.499 161.175 149.962 1.00 118.94 ? 624 ILE A N   1 
ATOM   4650 C CA  . ILE A 1 623 ? 152.583 161.000 149.006 1.00 121.24 ? 624 ILE A CA  1 
ATOM   4651 C C   . ILE A 1 623 ? 152.439 159.670 148.270 1.00 120.83 ? 624 ILE A C   1 
ATOM   4652 O O   . ILE A 1 623 ? 152.995 159.498 147.178 1.00 123.93 ? 624 ILE A O   1 
ATOM   4653 C CB  . ILE A 1 623 ? 153.940 161.139 149.737 1.00 127.31 ? 624 ILE A CB  1 
ATOM   4654 C CG1 . ILE A 1 623 ? 155.106 161.320 148.758 1.00 133.99 ? 624 ILE A CG1 1 
ATOM   4655 C CG2 . ILE A 1 623 ? 154.206 159.948 150.644 1.00 127.06 ? 624 ILE A CG2 1 
ATOM   4656 C CD1 . ILE A 1 623 ? 155.060 162.614 147.981 1.00 129.21 ? 624 ILE A CD1 1 
ATOM   4657 N N   . SER A 1 624 ? 151.665 158.733 148.825 1.00 119.66 ? 625 SER A N   1 
ATOM   4658 C CA  . SER A 1 624 ? 151.457 157.449 148.166 1.00 120.01 ? 625 SER A CA  1 
ATOM   4659 C C   . SER A 1 624 ? 150.540 157.589 146.958 1.00 115.30 ? 625 SER A C   1 
ATOM   4660 O O   . SER A 1 624 ? 150.786 156.989 145.905 1.00 117.90 ? 625 SER A O   1 
ATOM   4661 C CB  . SER A 1 624 ? 150.889 156.442 149.162 1.00 117.70 ? 625 SER A CB  1 
ATOM   4662 O OG  . SER A 1 624 ? 150.640 155.200 148.534 1.00 121.97 ? 625 SER A OG  1 
ATOM   4663 N N   . GLY A 1 625 ? 149.470 158.373 147.092 1.00 114.91 ? 626 GLY A N   1 
ATOM   4664 C CA  . GLY A 1 625 ? 148.613 158.629 145.947 1.00 118.02 ? 626 GLY A CA  1 
ATOM   4665 C C   . GLY A 1 625 ? 149.219 159.629 144.981 1.00 121.15 ? 626 GLY A C   1 
ATOM   4666 O O   . GLY A 1 625 ? 148.874 159.651 143.797 1.00 120.68 ? 626 GLY A O   1 
ATOM   4667 N N   . LEU A 1 626 ? 150.130 160.471 145.473 1.00 123.69 ? 627 LEU A N   1 
ATOM   4668 C CA  . LEU A 1 626 ? 150.765 161.468 144.620 1.00 119.13 ? 627 LEU A CA  1 
ATOM   4669 C C   . LEU A 1 626 ? 151.821 160.846 143.717 1.00 117.32 ? 627 LEU A C   1 
ATOM   4670 O O   . LEU A 1 626 ? 152.022 161.309 142.589 1.00 123.23 ? 627 LEU A O   1 
ATOM   4671 C CB  . LEU A 1 626 ? 151.384 162.569 145.484 1.00 117.51 ? 627 LEU A CB  1 
ATOM   4672 C CG  . LEU A 1 626 ? 152.037 163.780 144.815 1.00 124.04 ? 627 LEU A CG  1 
ATOM   4673 C CD1 . LEU A 1 626 ? 151.009 164.567 144.024 1.00 124.29 ? 627 LEU A CD1 1 
ATOM   4674 C CD2 . LEU A 1 626 ? 152.710 164.664 145.851 1.00 126.29 ? 627 LEU A CD2 1 
ATOM   4675 N N   . ALA A 1 627 ? 152.497 159.796 144.187 1.00 118.14 ? 628 ALA A N   1 
ATOM   4676 C CA  . ALA A 1 627 ? 153.608 159.229 143.430 1.00 120.13 ? 628 ALA A CA  1 
ATOM   4677 C C   . ALA A 1 627 ? 153.113 158.386 142.261 1.00 120.77 ? 628 ALA A C   1 
ATOM   4678 O O   . ALA A 1 627 ? 153.530 158.593 141.115 1.00 120.02 ? 628 ALA A O   1 
ATOM   4679 C CB  . ALA A 1 627 ? 154.501 158.402 144.354 1.00 116.46 ? 628 ALA A CB  1 
ATOM   4680 N N   . MET A 1 628 ? 152.229 157.423 142.529 1.00 121.77 ? 629 MET A N   1 
ATOM   4681 C CA  . MET A 1 628 ? 151.723 156.571 141.458 1.00 124.39 ? 629 MET A CA  1 
ATOM   4682 C C   . MET A 1 628 ? 150.686 157.299 140.611 1.00 126.46 ? 629 MET A C   1 
ATOM   4683 O O   . MET A 1 628 ? 150.551 157.010 139.414 1.00 129.92 ? 629 MET A O   1 
ATOM   4684 C CB  . MET A 1 628 ? 151.135 155.284 142.047 1.00 120.65 ? 629 MET A CB  1 
ATOM   4685 C CG  . MET A 1 628 ? 150.665 154.261 141.018 1.00 122.04 ? 629 MET A CG  1 
ATOM   4686 S SD  . MET A 1 628 ? 149.983 152.780 141.755 1.00 128.11 ? 629 MET A SD  1 
ATOM   4687 C CE  . MET A 1 628 ? 148.453 153.459 142.366 1.00 115.24 ? 629 MET A CE  1 
ATOM   4688 N N   . GLY A 1 629 ? 149.969 158.255 141.209 1.00 123.98 ? 630 GLY A N   1 
ATOM   4689 C CA  . GLY A 1 629 ? 148.960 158.997 140.469 1.00 124.08 ? 630 GLY A CA  1 
ATOM   4690 C C   . GLY A 1 629 ? 149.541 159.847 139.355 1.00 130.17 ? 630 GLY A C   1 
ATOM   4691 O O   . GLY A 1 629 ? 148.911 160.033 138.313 1.00 137.66 ? 630 GLY A O   1 
ATOM   4692 N N   . LEU A 1 630 ? 150.752 160.368 139.557 1.00 126.65 ? 631 LEU A N   1 
ATOM   4693 C CA  . LEU A 1 630 ? 151.439 161.058 138.470 1.00 129.15 ? 631 LEU A CA  1 
ATOM   4694 C C   . LEU A 1 630 ? 152.153 160.073 137.552 1.00 134.15 ? 631 LEU A C   1 
ATOM   4695 O O   . LEU A 1 630 ? 152.545 160.433 136.437 1.00 140.10 ? 631 LEU A O   1 
ATOM   4696 C CB  . LEU A 1 630 ? 152.423 162.094 139.020 1.00 124.20 ? 631 LEU A CB  1 
ATOM   4697 C CG  . LEU A 1 630 ? 151.961 163.520 139.358 1.00 122.53 ? 631 LEU A CG  1 
ATOM   4698 C CD1 . LEU A 1 630 ? 151.512 164.226 138.089 1.00 125.36 ? 631 LEU A CD1 1 
ATOM   4699 C CD2 . LEU A 1 630 ? 150.865 163.585 140.409 1.00 124.22 ? 631 LEU A CD2 1 
ATOM   4700 N N   . PHE A 1 631 ? 152.339 158.828 137.997 1.00 131.72 ? 632 PHE A N   1 
ATOM   4701 C CA  . PHE A 1 631 ? 152.940 157.823 137.124 1.00 132.86 ? 632 PHE A CA  1 
ATOM   4702 C C   . PHE A 1 631 ? 151.930 157.310 136.104 1.00 136.10 ? 632 PHE A C   1 
ATOM   4703 O O   . PHE A 1 631 ? 152.274 157.077 134.939 1.00 142.69 ? 632 PHE A O   1 
ATOM   4704 C CB  . PHE A 1 631 ? 153.521 156.678 137.959 1.00 133.18 ? 632 PHE A CB  1 
ATOM   4705 C CG  . PHE A 1 631 ? 153.689 155.387 137.201 1.00 137.26 ? 632 PHE A CG  1 
ATOM   4706 C CD1 . PHE A 1 631 ? 154.744 155.219 136.317 1.00 140.30 ? 632 PHE A CD1 1 
ATOM   4707 C CD2 . PHE A 1 631 ? 152.823 154.323 137.410 1.00 132.23 ? 632 PHE A CD2 1 
ATOM   4708 C CE1 . PHE A 1 631 ? 154.908 154.032 135.627 1.00 133.51 ? 632 PHE A CE1 1 
ATOM   4709 C CE2 . PHE A 1 631 ? 152.982 153.137 136.721 1.00 131.17 ? 632 PHE A CE2 1 
ATOM   4710 C CZ  . PHE A 1 631 ? 154.026 152.991 135.831 1.00 129.78 ? 632 PHE A CZ  1 
ATOM   4711 N N   . TYR A 1 632 ? 150.678 157.113 136.528 1.00 132.45 ? 633 TYR A N   1 
ATOM   4712 C CA  . TYR A 1 632 ? 149.617 156.784 135.579 1.00 137.00 ? 633 TYR A CA  1 
ATOM   4713 C C   . TYR A 1 632 ? 149.288 157.965 134.675 1.00 142.13 ? 633 TYR A C   1 
ATOM   4714 O O   . TYR A 1 632 ? 148.979 157.781 133.494 1.00 149.87 ? 633 TYR A O   1 
ATOM   4715 C CB  . TYR A 1 632 ? 148.357 156.321 136.315 1.00 135.05 ? 633 TYR A CB  1 
ATOM   4716 C CG  . TYR A 1 632 ? 148.439 154.949 136.949 1.00 134.71 ? 633 TYR A CG  1 
ATOM   4717 C CD1 . TYR A 1 632 ? 149.436 154.051 136.590 1.00 136.80 ? 633 TYR A CD1 1 
ATOM   4718 C CD2 . TYR A 1 632 ? 147.511 154.551 137.902 1.00 133.77 ? 633 TYR A CD2 1 
ATOM   4719 C CE1 . TYR A 1 632 ? 149.508 152.795 137.166 1.00 133.56 ? 633 TYR A CE1 1 
ATOM   4720 C CE2 . TYR A 1 632 ? 147.573 153.296 138.484 1.00 134.10 ? 633 TYR A CE2 1 
ATOM   4721 C CZ  . TYR A 1 632 ? 148.575 152.424 138.112 1.00 133.59 ? 633 TYR A CZ  1 
ATOM   4722 O OH  . TYR A 1 632 ? 148.645 151.176 138.688 1.00 138.20 ? 633 TYR A OH  1 
ATOM   4723 N N   . LEU A 1 633 ? 149.340 159.186 135.212 1.00 138.96 ? 634 LEU A N   1 
ATOM   4724 C CA  . LEU A 1 633 ? 148.893 160.348 134.450 1.00 145.43 ? 634 LEU A CA  1 
ATOM   4725 C C   . LEU A 1 633 ? 149.887 160.752 133.368 1.00 146.73 ? 634 LEU A C   1 
ATOM   4726 O O   . LEU A 1 633 ? 149.475 161.113 132.260 1.00 150.41 ? 634 LEU A O   1 
ATOM   4727 C CB  . LEU A 1 633 ? 148.644 161.527 135.391 1.00 148.88 ? 634 LEU A CB  1 
ATOM   4728 C CG  . LEU A 1 633 ? 148.015 162.784 134.786 1.00 155.43 ? 634 LEU A CG  1 
ATOM   4729 C CD1 . LEU A 1 633 ? 146.621 162.486 134.260 1.00 151.97 ? 634 LEU A CD1 1 
ATOM   4730 C CD2 . LEU A 1 633 ? 147.981 163.911 135.805 1.00 148.13 ? 634 LEU A CD2 1 
ATOM   4731 N N   . LEU A 1 634 ? 151.184 160.718 133.665 1.00 141.95 ? 635 LEU A N   1 
ATOM   4732 C CA  . LEU A 1 634 ? 152.182 161.258 132.749 1.00 143.71 ? 635 LEU A CA  1 
ATOM   4733 C C   . LEU A 1 634 ? 152.431 160.357 131.544 1.00 148.53 ? 635 LEU A C   1 
ATOM   4734 O O   . LEU A 1 634 ? 152.537 160.847 130.415 1.00 151.29 ? 635 LEU A O   1 
ATOM   4735 C CB  . LEU A 1 634 ? 153.495 161.513 133.494 1.00 140.15 ? 635 LEU A CB  1 
ATOM   4736 C CG  . LEU A 1 634 ? 154.624 162.164 132.697 1.00 138.51 ? 635 LEU A CG  1 
ATOM   4737 C CD1 . LEU A 1 634 ? 154.218 163.554 132.249 1.00 134.92 ? 635 LEU A CD1 1 
ATOM   4738 C CD2 . LEU A 1 634 ? 155.898 162.214 133.524 1.00 139.97 ? 635 LEU A CD2 1 
ATOM   4739 N N   . GLU A 1 635 ? 152.520 159.046 131.755 1.00 147.81 ? 636 GLU A N   1 
ATOM   4740 C CA  . GLU A 1 635 ? 153.004 158.127 130.728 1.00 150.41 ? 636 GLU A CA  1 
ATOM   4741 C C   . GLU A 1 635 ? 152.077 156.931 130.495 1.00 147.04 ? 636 GLU A C   1 
ATOM   4742 O O   . GLU A 1 635 ? 152.522 155.796 130.306 1.00 145.97 ? 636 GLU A O   1 
ATOM   4743 C CB  . GLU A 1 635 ? 154.439 157.699 131.051 1.00 150.75 ? 636 GLU A CB  1 
ATOM   4744 C CG  . GLU A 1 635 ? 154.665 156.893 132.338 1.00 156.12 ? 636 GLU A CG  1 
ATOM   4745 C CD  . GLU A 1 635 ? 156.131 156.592 132.572 1.00 163.98 ? 636 GLU A CD  1 
ATOM   4746 O OE1 . GLU A 1 635 ? 156.965 157.028 131.750 1.00 163.32 ? 636 GLU A OE1 1 
ATOM   4747 O OE2 . GLU A 1 635 ? 156.453 155.925 133.576 1.00 167.39 ? 636 GLU A OE2 1 
ATOM   4748 N N   . TYR A 1 636 ? 150.772 157.176 130.423 1.00 144.69 ? 637 TYR A N   1 
ATOM   4749 C CA  . TYR A 1 636 ? 149.833 156.161 129.970 1.00 149.28 ? 637 TYR A CA  1 
ATOM   4750 C C   . TYR A 1 636 ? 149.794 156.183 128.447 1.00 150.59 ? 637 TYR A C   1 
ATOM   4751 O O   . TYR A 1 636 ? 149.802 157.256 127.834 1.00 144.34 ? 637 TYR A O   1 
ATOM   4752 C CB  . TYR A 1 636 ? 148.427 156.378 130.554 1.00 151.56 ? 637 TYR A CB  1 
ATOM   4753 C CG  . TYR A 1 636 ? 147.682 157.612 130.073 1.00 156.93 ? 637 TYR A CG  1 
ATOM   4754 C CD1 . TYR A 1 636 ? 147.839 158.837 130.710 1.00 156.88 ? 637 TYR A CD1 1 
ATOM   4755 C CD2 . TYR A 1 636 ? 146.770 157.534 129.021 1.00 156.34 ? 637 TYR A CD2 1 
ATOM   4756 C CE1 . TYR A 1 636 ? 147.150 159.960 130.283 1.00 158.77 ? 637 TYR A CE1 1 
ATOM   4757 C CE2 . TYR A 1 636 ? 146.077 158.651 128.587 1.00 158.52 ? 637 TYR A CE2 1 
ATOM   4758 C CZ  . TYR A 1 636 ? 146.270 159.860 129.224 1.00 158.84 ? 637 TYR A CZ  1 
ATOM   4759 O OH  . TYR A 1 636 ? 145.581 160.973 128.801 1.00 148.84 ? 637 TYR A OH  1 
ATOM   4760 N N   . SER A 1 637 ? 149.770 155.001 127.837 1.00 141.94 ? 638 SER A N   1 
ATOM   4761 C CA  . SER A 1 637 ? 149.721 154.911 126.386 1.00 125.54 ? 638 SER A CA  1 
ATOM   4762 C C   . SER A 1 637 ? 149.083 153.590 125.987 1.00 122.08 ? 638 SER A C   1 
ATOM   4763 O O   . SER A 1 637 ? 149.558 152.516 126.363 1.00 117.59 ? 638 SER A O   1 
ATOM   4764 C CB  . SER A 1 637 ? 151.118 155.041 125.766 1.00 119.03 ? 638 SER A CB  1 
ATOM   4765 O OG  . SER A 1 637 ? 152.071 154.294 126.499 1.00 127.71 ? 638 SER A OG  1 
ATOM   4766 N N   . GLN A 1 638 ? 148.001 153.689 125.217 1.00 123.22 ? 639 GLN A N   1 
ATOM   4767 C CA  . GLN A 1 638 ? 147.302 152.528 124.686 1.00 115.72 ? 639 GLN A CA  1 
ATOM   4768 C C   . GLN A 1 638 ? 146.527 152.993 123.462 1.00 119.03 ? 639 GLN A C   1 
ATOM   4769 O O   . GLN A 1 638 ? 145.981 154.098 123.458 1.00 121.90 ? 639 GLN A O   1 
ATOM   4770 C CB  . GLN A 1 638 ? 146.372 151.906 125.739 1.00 113.27 ? 639 GLN A CB  1 
ATOM   4771 C CG  . GLN A 1 638 ? 146.039 150.429 125.524 1.00 126.57 ? 639 GLN A CG  1 
ATOM   4772 C CD  . GLN A 1 638 ? 144.973 150.193 124.473 1.00 132.02 ? 639 GLN A CD  1 
ATOM   4773 O OE1 . GLN A 1 638 ? 144.179 151.079 124.169 1.00 134.23 ? 639 GLN A OE1 1 
ATOM   4774 N NE2 . GLN A 1 638 ? 144.955 148.991 123.910 1.00 125.81 ? 639 GLN A NE2 1 
ATOM   4775 N N   . VAL A 1 639 ? 146.484 152.145 122.436 1.00 119.17 ? 640 VAL A N   1 
ATOM   4776 C CA  . VAL A 1 639 ? 145.951 152.516 121.126 1.00 116.88 ? 640 VAL A CA  1 
ATOM   4777 C C   . VAL A 1 639 ? 144.429 152.622 121.214 1.00 120.38 ? 640 VAL A C   1 
ATOM   4778 O O   . VAL A 1 639 ? 143.732 151.608 121.316 1.00 122.84 ? 640 VAL A O   1 
ATOM   4779 C CB  . VAL A 1 639 ? 146.375 151.510 120.051 1.00 113.43 ? 640 VAL A CB  1 
ATOM   4780 C CG1 . VAL A 1 639 ? 145.800 151.896 118.702 1.00 115.21 ? 640 VAL A CG1 1 
ATOM   4781 C CG2 . VAL A 1 639 ? 147.890 151.418 119.984 1.00 112.86 ? 640 VAL A CG2 1 
ATOM   4782 N N   . GLN A 1 640 ? 143.911 153.850 121.171 1.00 115.74 ? 641 GLN A N   1 
ATOM   4783 C CA  . GLN A 1 640 ? 142.476 154.098 121.188 1.00 111.25 ? 641 GLN A CA  1 
ATOM   4784 C C   . GLN A 1 640 ? 142.110 155.073 120.079 1.00 111.29 ? 641 GLN A C   1 
ATOM   4785 O O   . GLN A 1 640 ? 142.820 156.051 119.829 1.00 118.93 ? 641 GLN A O   1 
ATOM   4786 C CB  . GLN A 1 640 ? 142.003 154.652 122.539 1.00 116.38 ? 641 GLN A CB  1 
ATOM   4787 C CG  . GLN A 1 640 ? 142.165 153.696 123.704 1.00 119.48 ? 641 GLN A CG  1 
ATOM   4788 C CD  . GLN A 1 640 ? 141.276 152.476 123.573 1.00 123.02 ? 641 GLN A CD  1 
ATOM   4789 O OE1 . GLN A 1 640 ? 140.132 152.574 123.130 1.00 123.69 ? 641 GLN A OE1 1 
ATOM   4790 N NE2 . GLN A 1 640 ? 141.795 151.318 123.961 1.00 122.99 ? 641 GLN A NE2 1 
ATOM   4791 N N   . LEU A 1 641 ? 140.988 154.797 119.418 1.00 105.97 ? 642 LEU A N   1 
ATOM   4792 C CA  . LEU A 1 641 ? 140.539 155.576 118.273 1.00 113.39 ? 642 LEU A CA  1 
ATOM   4793 C C   . LEU A 1 641 ? 139.090 155.991 118.492 1.00 125.08 ? 642 LEU A C   1 
ATOM   4794 O O   . LEU A 1 641 ? 138.250 155.190 118.907 1.00 127.04 ? 642 LEU A O   1 
ATOM   4795 C CB  . LEU A 1 641 ? 140.676 154.787 116.958 1.00 115.87 ? 642 LEU A CB  1 
ATOM   4796 C CG  . LEU A 1 641 ? 142.035 154.612 116.261 1.00 116.96 ? 642 LEU A CG  1 
ATOM   4797 C CD1 . LEU A 1 641 ? 142.974 153.660 116.981 1.00 119.50 ? 642 LEU A CD1 1 
ATOM   4798 C CD2 . LEU A 1 641 ? 141.824 154.118 114.851 1.00 118.55 ? 642 LEU A CD2 1 
ATOM   4799 N N   . VAL A 1 642 ? 138.804 157.263 118.212 1.00 128.61 ? 643 VAL A N   1 
ATOM   4800 C CA  . VAL A 1 642 ? 137.497 157.862 118.482 1.00 126.03 ? 643 VAL A CA  1 
ATOM   4801 C C   . VAL A 1 642 ? 136.975 158.514 117.207 1.00 126.21 ? 643 VAL A C   1 
ATOM   4802 O O   . VAL A 1 642 ? 137.699 159.263 116.542 1.00 128.95 ? 643 VAL A O   1 
ATOM   4803 C CB  . VAL A 1 642 ? 137.576 158.895 119.634 1.00 129.72 ? 643 VAL A CB  1 
ATOM   4804 C CG1 . VAL A 1 642 ? 136.242 159.602 119.843 1.00 128.10 ? 643 VAL A CG1 1 
ATOM   4805 C CG2 . VAL A 1 642 ? 138.022 158.237 120.937 1.00 124.54 ? 643 VAL A CG2 1 
ATOM   4806 N N   . GLU A 1 643 ? 135.716 158.226 116.865 1.00 121.34 ? 644 GLU A N   1 
ATOM   4807 C CA  . GLU A 1 643 ? 135.010 158.876 115.766 1.00 126.42 ? 644 GLU A CA  1 
ATOM   4808 C C   . GLU A 1 643 ? 133.941 159.797 116.336 1.00 130.18 ? 644 GLU A C   1 
ATOM   4809 O O   . GLU A 1 643 ? 133.306 159.467 117.343 1.00 137.57 ? 644 GLU A O   1 
ATOM   4810 C CB  . GLU A 1 643 ? 134.331 157.862 114.836 1.00 125.78 ? 644 GLU A CB  1 
ATOM   4811 C CG  . GLU A 1 643 ? 135.253 156.931 114.071 1.00 125.83 ? 644 GLU A CG  1 
ATOM   4812 C CD  . GLU A 1 643 ? 135.650 155.715 114.884 1.00 126.31 ? 644 GLU A CD  1 
ATOM   4813 O OE1 . GLU A 1 643 ? 135.164 155.570 116.026 1.00 126.07 ? 644 GLU A OE1 1 
ATOM   4814 O OE2 . GLU A 1 643 ? 136.416 154.880 114.373 1.00 121.87 ? 644 GLU A OE2 1 
ATOM   4815 N N   . SER A 1 644 ? 133.724 160.940 115.684 1.00 125.25 ? 645 SER A N   1 
ATOM   4816 C CA  . SER A 1 644 ? 132.708 161.877 116.148 1.00 128.73 ? 645 SER A CA  1 
ATOM   4817 C C   . SER A 1 644 ? 132.258 162.774 115.004 1.00 121.68 ? 645 SER A C   1 
ATOM   4818 O O   . SER A 1 644 ? 133.088 163.286 114.251 1.00 128.93 ? 645 SER A O   1 
ATOM   4819 C CB  . SER A 1 644 ? 133.234 162.740 117.303 1.00 132.19 ? 645 SER A CB  1 
ATOM   4820 O OG  . SER A 1 644 ? 134.416 163.425 116.928 1.00 131.34 ? 645 SER A OG  1 
ATOM   4821 N N   . GLY A 1 645 ? 130.943 162.968 114.890 1.00 113.31 ? 646 GLY A N   1 
ATOM   4822 C CA  . GLY A 1 645 ? 130.411 163.977 113.993 1.00 114.52 ? 646 GLY A CA  1 
ATOM   4823 C C   . GLY A 1 645 ? 129.290 163.557 113.062 1.00 121.51 ? 646 GLY A C   1 
ATOM   4824 O O   . GLY A 1 645 ? 128.804 164.378 112.279 1.00 123.65 ? 646 GLY A O   1 
ATOM   4825 N N   . GLY A 1 646 ? 128.862 162.298 113.129 1.00 128.14 ? 647 GLY A N   1 
ATOM   4826 C CA  . GLY A 1 646 ? 127.834 161.811 112.218 1.00 129.75 ? 647 GLY A CA  1 
ATOM   4827 C C   . GLY A 1 646 ? 126.445 162.223 112.673 1.00 135.08 ? 647 GLY A C   1 
ATOM   4828 O O   . GLY A 1 646 ? 126.077 162.027 113.836 1.00 140.82 ? 647 GLY A O   1 
ATOM   4829 N N   . ALA A 1 647 ? 125.668 162.783 111.754 1.00 134.39 ? 648 ALA A N   1 
ATOM   4830 C CA  . ALA A 1 647 ? 124.366 163.345 112.100 1.00 139.38 ? 648 ALA A CA  1 
ATOM   4831 C C   . ALA A 1 647 ? 123.438 163.216 110.895 1.00 137.24 ? 648 ALA A C   1 
ATOM   4832 O O   . ALA A 1 647 ? 123.718 162.465 109.955 1.00 134.66 ? 648 ALA A O   1 
ATOM   4833 C CB  . ALA A 1 647 ? 124.522 164.799 112.578 1.00 139.60 ? 648 ALA A CB  1 
ATOM   4834 N N   . LEU A 1 648 ? 122.327 163.951 110.928 1.00 137.78 ? 649 LEU A N   1 
ATOM   4835 C CA  . LEU A 1 648 ? 121.308 163.916 109.885 1.00 136.70 ? 649 LEU A CA  1 
ATOM   4836 C C   . LEU A 1 648 ? 121.626 164.975 108.837 1.00 140.54 ? 649 LEU A C   1 
ATOM   4837 O O   . LEU A 1 648 ? 121.489 166.175 109.101 1.00 141.75 ? 649 LEU A O   1 
ATOM   4838 C CB  . LEU A 1 648 ? 119.914 164.155 110.468 1.00 137.42 ? 649 LEU A CB  1 
ATOM   4839 C CG  . LEU A 1 648 ? 119.082 163.024 111.091 1.00 142.22 ? 649 LEU A CG  1 
ATOM   4840 C CD1 . LEU A 1 648 ? 118.737 161.973 110.044 1.00 141.45 ? 649 LEU A CD1 1 
ATOM   4841 C CD2 . LEU A 1 648 ? 119.729 162.384 112.320 1.00 136.88 ? 649 LEU A CD2 1 
ATOM   4842 N N   . VAL A 1 649 ? 122.046 164.533 107.654 1.00 142.03 ? 650 VAL A N   1 
ATOM   4843 C CA  . VAL A 1 649 ? 122.427 165.423 106.563 1.00 146.50 ? 650 VAL A CA  1 
ATOM   4844 C C   . VAL A 1 649 ? 121.508 165.161 105.380 1.00 149.23 ? 650 VAL A C   1 
ATOM   4845 O O   . VAL A 1 649 ? 121.269 164.003 105.018 1.00 146.92 ? 650 VAL A O   1 
ATOM   4846 C CB  . VAL A 1 649 ? 123.901 165.232 106.148 1.00 149.83 ? 650 VAL A CB  1 
ATOM   4847 C CG1 . VAL A 1 649 ? 124.349 166.358 105.225 1.00 152.07 ? 650 VAL A CG1 1 
ATOM   4848 C CG2 . VAL A 1 649 ? 124.801 165.163 107.369 1.00 140.68 ? 650 VAL A CG2 1 
ATOM   4849 N N   . GLN A 1 650 ? 120.987 166.234 104.788 1.00 153.60 ? 651 GLN A N   1 
ATOM   4850 C CA  . GLN A 1 650 ? 120.221 166.122 103.560 1.00 160.13 ? 651 GLN A CA  1 
ATOM   4851 C C   . GLN A 1 650 ? 121.140 165.711 102.408 1.00 161.43 ? 651 GLN A C   1 
ATOM   4852 O O   . GLN A 1 650 ? 122.350 165.951 102.463 1.00 162.01 ? 651 GLN A O   1 
ATOM   4853 C CB  . GLN A 1 650 ? 119.539 167.453 103.243 1.00 167.98 ? 651 GLN A CB  1 
ATOM   4854 C CG  . GLN A 1 650 ? 118.207 167.652 103.955 1.00 172.49 ? 651 GLN A CG  1 
ATOM   4855 C CD  . GLN A 1 650 ? 117.084 166.835 103.343 1.00 172.78 ? 651 GLN A CD  1 
ATOM   4856 O OE1 . GLN A 1 650 ? 117.029 166.644 102.129 1.00 170.93 ? 651 GLN A OE1 1 
ATOM   4857 N NE2 . GLN A 1 650 ? 116.182 166.346 104.186 1.00 172.86 ? 651 GLN A NE2 1 
ATOM   4858 N N   . PRO A 1 651 ? 120.600 165.046 101.379 1.00 162.33 ? 652 PRO A N   1 
ATOM   4859 C CA  . PRO A 1 651 ? 121.426 164.687 100.216 1.00 160.66 ? 652 PRO A CA  1 
ATOM   4860 C C   . PRO A 1 651 ? 121.950 165.909 99.476  1.00 156.81 ? 652 PRO A C   1 
ATOM   4861 O O   . PRO A 1 651 ? 121.313 166.964 99.438  1.00 159.99 ? 652 PRO A O   1 
ATOM   4862 C CB  . PRO A 1 651 ? 120.470 163.878 99.333  1.00 166.13 ? 652 PRO A CB  1 
ATOM   4863 C CG  . PRO A 1 651 ? 119.430 163.367 100.249 1.00 167.26 ? 652 PRO A CG  1 
ATOM   4864 C CD  . PRO A 1 651 ? 119.296 164.355 101.365 1.00 159.32 ? 652 PRO A CD  1 
ATOM   4865 N N   . GLY A 1 652 ? 123.133 165.753 98.888  1.00 152.01 ? 653 GLY A N   1 
ATOM   4866 C CA  . GLY A 1 652 ? 123.777 166.824 98.162  1.00 157.20 ? 653 GLY A CA  1 
ATOM   4867 C C   . GLY A 1 652 ? 124.633 167.748 98.999  1.00 160.07 ? 653 GLY A C   1 
ATOM   4868 O O   . GLY A 1 652 ? 125.230 168.680 98.445  1.00 162.82 ? 653 GLY A O   1 
ATOM   4869 N N   . GLY A 1 653 ? 124.715 167.524 100.305 1.00 158.99 ? 654 GLY A N   1 
ATOM   4870 C CA  . GLY A 1 653 ? 125.504 168.365 101.180 1.00 159.01 ? 654 GLY A CA  1 
ATOM   4871 C C   . GLY A 1 653 ? 126.944 167.904 101.286 1.00 152.59 ? 654 GLY A C   1 
ATOM   4872 O O   . GLY A 1 653 ? 127.469 167.187 100.431 1.00 151.23 ? 654 GLY A O   1 
ATOM   4873 N N   . SER A 1 654 ? 127.595 168.344 102.360 1.00 146.30 ? 655 SER A N   1 
ATOM   4874 C CA  . SER A 1 654 ? 128.968 167.969 102.654 1.00 144.40 ? 655 SER A CA  1 
ATOM   4875 C C   . SER A 1 654 ? 129.084 167.653 104.136 1.00 142.54 ? 655 SER A C   1 
ATOM   4876 O O   . SER A 1 654 ? 128.297 168.141 104.951 1.00 143.66 ? 655 SER A O   1 
ATOM   4877 C CB  . SER A 1 654 ? 129.955 169.079 102.270 1.00 150.43 ? 655 SER A CB  1 
ATOM   4878 O OG  . SER A 1 654 ? 129.666 169.597 100.983 1.00 149.46 ? 655 SER A OG  1 
ATOM   4879 N N   . LEU A 1 655 ? 130.073 166.832 104.481 1.00 136.67 ? 656 LEU A N   1 
ATOM   4880 C CA  . LEU A 1 655 ? 130.266 166.429 105.866 1.00 126.94 ? 656 LEU A CA  1 
ATOM   4881 C C   . LEU A 1 655 ? 131.752 166.256 106.135 1.00 123.70 ? 656 LEU A C   1 
ATOM   4882 O O   . LEU A 1 655 ? 132.550 166.072 105.215 1.00 130.00 ? 656 LEU A O   1 
ATOM   4883 C CB  . LEU A 1 655 ? 129.509 165.133 106.181 1.00 127.70 ? 656 LEU A CB  1 
ATOM   4884 C CG  . LEU A 1 655 ? 129.072 164.874 107.627 1.00 133.63 ? 656 LEU A CG  1 
ATOM   4885 C CD1 . LEU A 1 655 ? 128.379 166.092 108.221 1.00 130.99 ? 656 LEU A CD1 1 
ATOM   4886 C CD2 . LEU A 1 655 ? 128.194 163.637 107.720 1.00 137.67 ? 656 LEU A CD2 1 
ATOM   4887 N N   . ARG A 1 656 ? 132.120 166.320 107.412 1.00 116.03 ? 657 ARG A N   1 
ATOM   4888 C CA  . ARG A 1 656 ? 133.491 166.075 107.837 1.00 114.73 ? 657 ARG A CA  1 
ATOM   4889 C C   . ARG A 1 656 ? 133.472 165.163 109.052 1.00 118.64 ? 657 ARG A C   1 
ATOM   4890 O O   . ARG A 1 656 ? 132.764 165.441 110.024 1.00 118.56 ? 657 ARG A O   1 
ATOM   4891 C CB  . ARG A 1 656 ? 134.211 167.387 108.163 1.00 115.76 ? 657 ARG A CB  1 
ATOM   4892 C CG  . ARG A 1 656 ? 134.855 168.049 106.959 1.00 124.27 ? 657 ARG A CG  1 
ATOM   4893 C CD  . ARG A 1 656 ? 135.788 169.167 107.379 1.00 123.98 ? 657 ARG A CD  1 
ATOM   4894 N NE  . ARG A 1 656 ? 136.566 168.817 108.561 1.00 130.62 ? 657 ARG A NE  1 
ATOM   4895 C CZ  . ARG A 1 656 ? 137.840 168.453 108.540 1.00 130.18 ? 657 ARG A CZ  1 
ATOM   4896 N NH1 . ARG A 1 656 ? 138.516 168.370 107.406 1.00 124.85 ? 657 ARG A NH1 1 
ATOM   4897 N NH2 . ARG A 1 656 ? 138.453 168.169 109.685 1.00 129.56 ? 657 ARG A NH2 1 
ATOM   4898 N N   . LEU A 1 657 ? 134.245 164.081 108.999 1.00 122.44 ? 658 LEU A N   1 
ATOM   4899 C CA  . LEU A 1 657 ? 134.309 163.114 110.083 1.00 114.57 ? 658 LEU A CA  1 
ATOM   4900 C C   . LEU A 1 657 ? 135.750 162.969 110.547 1.00 117.95 ? 658 LEU A C   1 
ATOM   4901 O O   . LEU A 1 657 ? 136.665 162.824 109.728 1.00 121.18 ? 658 LEU A O   1 
ATOM   4902 C CB  . LEU A 1 657 ? 133.757 161.758 109.645 1.00 122.01 ? 658 LEU A CB  1 
ATOM   4903 C CG  . LEU A 1 657 ? 132.292 161.529 110.019 1.00 128.51 ? 658 LEU A CG  1 
ATOM   4904 C CD1 . LEU A 1 657 ? 131.800 160.176 109.524 1.00 125.10 ? 658 LEU A CD1 1 
ATOM   4905 C CD2 . LEU A 1 657 ? 132.085 161.678 111.512 1.00 130.02 ? 658 LEU A CD2 1 
ATOM   4906 N N   . SER A 1 658 ? 135.947 162.999 111.862 1.00 119.62 ? 659 SER A N   1 
ATOM   4907 C CA  . SER A 1 658 ? 137.277 163.038 112.456 1.00 126.97 ? 659 SER A CA  1 
ATOM   4908 C C   . SER A 1 658 ? 137.529 161.764 113.247 1.00 128.12 ? 659 SER A C   1 
ATOM   4909 O O   . SER A 1 658 ? 136.768 161.439 114.164 1.00 125.22 ? 659 SER A O   1 
ATOM   4910 C CB  . SER A 1 658 ? 137.433 164.258 113.365 1.00 123.04 ? 659 SER A CB  1 
ATOM   4911 O OG  . SER A 1 658 ? 136.876 164.006 114.642 1.00 118.85 ? 659 SER A OG  1 
ATOM   4912 N N   . CYS A 1 659 ? 138.598 161.054 112.892 1.00 132.05 ? 660 CYS A N   1 
ATOM   4913 C CA  . CYS A 1 659 ? 139.132 159.957 113.686 1.00 129.37 ? 660 CYS A CA  1 
ATOM   4914 C C   . CYS A 1 659 ? 140.351 160.463 114.448 1.00 123.59 ? 660 CYS A C   1 
ATOM   4915 O O   . CYS A 1 659 ? 141.330 160.927 113.843 1.00 128.01 ? 660 CYS A O   1 
ATOM   4916 C CB  . CYS A 1 659 ? 139.489 158.770 112.792 1.00 133.63 ? 660 CYS A CB  1 
ATOM   4917 S SG  . CYS A 1 659 ? 140.195 157.304 113.589 1.00 149.54 ? 660 CYS A SG  1 
ATOM   4918 N N   . ALA A 1 660 ? 140.275 160.391 115.773 1.00 121.09 ? 661 ALA A N   1 
ATOM   4919 C CA  . ALA A 1 660 ? 141.342 160.831 116.660 1.00 124.67 ? 661 ALA A CA  1 
ATOM   4920 C C   . ALA A 1 660 ? 141.994 159.609 117.285 1.00 121.91 ? 661 ALA A C   1 
ATOM   4921 O O   . ALA A 1 660 ? 141.298 158.701 117.754 1.00 129.74 ? 661 ALA A O   1 
ATOM   4922 C CB  . ALA A 1 660 ? 140.806 161.765 117.746 1.00 132.19 ? 661 ALA A CB  1 
ATOM   4923 N N   . ALA A 1 661 ? 143.323 159.591 117.293 1.00 110.66 ? 662 ALA A N   1 
ATOM   4924 C CA  . ALA A 1 661 ? 144.089 158.427 117.703 1.00 115.42 ? 662 ALA A CA  1 
ATOM   4925 C C   . ALA A 1 661 ? 144.976 158.760 118.893 1.00 112.49 ? 662 ALA A C   1 
ATOM   4926 O O   . ALA A 1 661 ? 145.474 159.881 119.025 1.00 120.08 ? 662 ALA A O   1 
ATOM   4927 C CB  . ALA A 1 661 ? 144.947 157.906 116.549 1.00 117.36 ? 662 ALA A CB  1 
ATOM   4928 N N   . SER A 1 662 ? 145.168 157.769 119.762 1.00 110.15 ? 663 SER A N   1 
ATOM   4929 C CA  . SER A 1 662 ? 146.046 157.906 120.913 1.00 110.88 ? 663 SER A CA  1 
ATOM   4930 C C   . SER A 1 662 ? 146.821 156.614 121.114 1.00 113.04 ? 663 SER A C   1 
ATOM   4931 O O   . SER A 1 662 ? 146.275 155.522 120.934 1.00 111.06 ? 663 SER A O   1 
ATOM   4932 C CB  . SER A 1 662 ? 145.258 158.247 122.183 1.00 123.79 ? 663 SER A CB  1 
ATOM   4933 O OG  . SER A 1 662 ? 144.271 157.266 122.448 1.00 126.10 ? 663 SER A OG  1 
ATOM   4934 N N   . GLY A 1 663 ? 148.098 156.747 121.481 1.00 123.80 ? 664 GLY A N   1 
ATOM   4935 C CA  . GLY A 1 663 ? 148.961 155.619 121.795 1.00 127.14 ? 664 GLY A CA  1 
ATOM   4936 C C   . GLY A 1 663 ? 150.088 155.411 120.801 1.00 118.79 ? 664 GLY A C   1 
ATOM   4937 O O   . GLY A 1 663 ? 151.147 154.894 121.173 1.00 112.82 ? 664 GLY A O   1 
ATOM   4938 N N   . PHE A 1 664 ? 149.884 155.803 119.552 1.00 113.65 ? 665 PHE A N   1 
ATOM   4939 C CA  . PHE A 1 664 ? 150.833 155.563 118.477 1.00 115.44 ? 665 PHE A CA  1 
ATOM   4940 C C   . PHE A 1 664 ? 150.955 156.827 117.641 1.00 122.75 ? 665 PHE A C   1 
ATOM   4941 O O   . PHE A 1 664 ? 150.028 157.645 117.607 1.00 122.07 ? 665 PHE A O   1 
ATOM   4942 C CB  . PHE A 1 664 ? 150.399 154.378 117.597 1.00 110.54 ? 665 PHE A CB  1 
ATOM   4943 C CG  . PHE A 1 664 ? 149.155 154.631 116.784 1.00 111.37 ? 665 PHE A CG  1 
ATOM   4944 C CD1 . PHE A 1 664 ? 147.898 154.541 117.362 1.00 118.06 ? 665 PHE A CD1 1 
ATOM   4945 C CD2 . PHE A 1 664 ? 149.244 154.940 115.435 1.00 119.20 ? 665 PHE A CD2 1 
ATOM   4946 C CE1 . PHE A 1 664 ? 146.759 154.767 116.618 1.00 121.61 ? 665 PHE A CE1 1 
ATOM   4947 C CE2 . PHE A 1 664 ? 148.109 155.175 114.687 1.00 122.83 ? 665 PHE A CE2 1 
ATOM   4948 C CZ  . PHE A 1 664 ? 146.864 155.084 115.279 1.00 123.12 ? 665 PHE A CZ  1 
ATOM   4949 N N   . PRO A 1 665 ? 152.089 157.025 116.963 1.00 122.10 ? 666 PRO A N   1 
ATOM   4950 C CA  . PRO A 1 665 ? 152.179 158.132 116.005 1.00 121.18 ? 666 PRO A CA  1 
ATOM   4951 C C   . PRO A 1 665 ? 151.528 157.784 114.675 1.00 122.14 ? 666 PRO A C   1 
ATOM   4952 O O   . PRO A 1 665 ? 151.663 156.672 114.159 1.00 122.13 ? 666 PRO A O   1 
ATOM   4953 C CB  . PRO A 1 665 ? 153.690 158.345 115.853 1.00 111.10 ? 666 PRO A CB  1 
ATOM   4954 C CG  . PRO A 1 665 ? 154.278 157.017 116.124 1.00 116.25 ? 666 PRO A CG  1 
ATOM   4955 C CD  . PRO A 1 665 ? 153.394 156.362 117.153 1.00 116.54 ? 666 PRO A CD  1 
ATOM   4956 N N   . VAL A 1 666 ? 150.807 158.763 114.122 1.00 118.23 ? 667 VAL A N   1 
ATOM   4957 C CA  . VAL A 1 666 ? 150.073 158.576 112.873 1.00 118.04 ? 667 VAL A CA  1 
ATOM   4958 C C   . VAL A 1 666 ? 150.973 158.788 111.658 1.00 122.65 ? 667 VAL A C   1 
ATOM   4959 O O   . VAL A 1 666 ? 150.610 158.379 110.542 1.00 123.44 ? 667 VAL A O   1 
ATOM   4960 C CB  . VAL A 1 666 ? 148.849 159.522 112.906 1.00 122.17 ? 667 VAL A CB  1 
ATOM   4961 C CG1 . VAL A 1 666 ? 147.822 159.221 111.806 1.00 118.48 ? 667 VAL A CG1 1 
ATOM   4962 C CG2 . VAL A 1 666 ? 148.180 159.466 114.273 1.00 124.56 ? 667 VAL A CG2 1 
ATOM   4963 N N   . ASN A 1 667 ? 152.167 159.356 111.852 1.00 121.35 ? 668 ASN A N   1 
ATOM   4964 C CA  . ASN A 1 667 ? 153.010 159.763 110.729 1.00 121.40 ? 668 ASN A CA  1 
ATOM   4965 C C   . ASN A 1 667 ? 153.603 158.570 109.985 1.00 118.70 ? 668 ASN A C   1 
ATOM   4966 O O   . ASN A 1 667 ? 153.772 158.625 108.761 1.00 121.28 ? 668 ASN A O   1 
ATOM   4967 C CB  . ASN A 1 667 ? 154.123 160.685 111.226 1.00 125.20 ? 668 ASN A CB  1 
ATOM   4968 C CG  . ASN A 1 667 ? 154.839 161.395 110.095 1.00 127.30 ? 668 ASN A CG  1 
ATOM   4969 O OD1 . ASN A 1 667 ? 154.206 161.980 109.217 1.00 121.37 ? 668 ASN A OD1 1 
ATOM   4970 N ND2 . ASN A 1 667 ? 156.166 161.349 110.112 1.00 124.02 ? 668 ASN A ND2 1 
ATOM   4971 N N   . ARG A 1 668 ? 153.927 157.489 110.691 1.00 114.01 ? 669 ARG A N   1 
ATOM   4972 C CA  . ARG A 1 668 ? 154.596 156.351 110.073 1.00 118.65 ? 669 ARG A CA  1 
ATOM   4973 C C   . ARG A 1 668 ? 153.673 155.164 109.817 1.00 121.63 ? 669 ARG A C   1 
ATOM   4974 O O   . ARG A 1 668 ? 154.093 154.200 109.169 1.00 125.93 ? 669 ARG A O   1 
ATOM   4975 C CB  . ARG A 1 668 ? 155.789 155.912 110.923 1.00 122.45 ? 669 ARG A CB  1 
ATOM   4976 C CG  . ARG A 1 668 ? 156.914 156.930 110.958 1.00 131.36 ? 669 ARG A CG  1 
ATOM   4977 C CD  . ARG A 1 668 ? 158.093 156.439 111.779 1.00 142.25 ? 669 ARG A CD  1 
ATOM   4978 N NE  . ARG A 1 668 ? 159.133 157.454 111.888 1.00 154.37 ? 669 ARG A NE  1 
ATOM   4979 C CZ  . ARG A 1 668 ? 160.127 157.606 111.022 1.00 157.11 ? 669 ARG A CZ  1 
ATOM   4980 N NH1 . ARG A 1 668 ? 160.246 156.822 109.963 1.00 157.91 ? 669 ARG A NH1 1 
ATOM   4981 N NH2 . ARG A 1 668 ? 161.022 158.569 111.223 1.00 150.66 ? 669 ARG A NH2 1 
ATOM   4982 N N   . TYR A 1 669 ? 152.434 155.205 110.298 1.00 119.47 ? 670 TYR A N   1 
ATOM   4983 C CA  . TYR A 1 669 ? 151.474 154.140 110.046 1.00 120.31 ? 670 TYR A CA  1 
ATOM   4984 C C   . TYR A 1 669 ? 150.324 154.657 109.192 1.00 125.08 ? 670 TYR A C   1 
ATOM   4985 O O   . TYR A 1 669 ? 150.096 155.864 109.079 1.00 125.49 ? 670 TYR A O   1 
ATOM   4986 C CB  . TYR A 1 669 ? 150.923 153.533 111.346 1.00 125.14 ? 670 TYR A CB  1 
ATOM   4987 C CG  . TYR A 1 669 ? 151.904 152.678 112.118 1.00 125.29 ? 670 TYR A CG  1 
ATOM   4988 C CD1 . TYR A 1 669 ? 153.070 152.209 111.523 1.00 123.85 ? 670 TYR A CD1 1 
ATOM   4989 C CD2 . TYR A 1 669 ? 151.648 152.316 113.434 1.00 125.07 ? 670 TYR A CD2 1 
ATOM   4990 C CE1 . TYR A 1 669 ? 153.961 151.419 112.223 1.00 124.56 ? 670 TYR A CE1 1 
ATOM   4991 C CE2 . TYR A 1 669 ? 152.533 151.526 114.143 1.00 121.84 ? 670 TYR A CE2 1 
ATOM   4992 C CZ  . TYR A 1 669 ? 153.687 151.081 113.532 1.00 126.94 ? 670 TYR A CZ  1 
ATOM   4993 O OH  . TYR A 1 669 ? 154.571 150.294 114.235 1.00 138.02 ? 670 TYR A OH  1 
ATOM   4994 N N   . SER A 1 670 ? 149.604 153.716 108.588 1.00 118.99 ? 671 SER A N   1 
ATOM   4995 C CA  . SER A 1 670 ? 148.494 154.024 107.702 1.00 115.46 ? 671 SER A CA  1 
ATOM   4996 C C   . SER A 1 670 ? 147.165 153.968 108.447 1.00 122.03 ? 671 SER A C   1 
ATOM   4997 O O   . SER A 1 670 ? 147.047 153.371 109.520 1.00 123.69 ? 671 SER A O   1 
ATOM   4998 C CB  . SER A 1 670 ? 148.465 153.055 106.522 1.00 115.64 ? 671 SER A CB  1 
ATOM   4999 O OG  . SER A 1 670 ? 149.620 153.201 105.717 1.00 120.51 ? 671 SER A OG  1 
ATOM   5000 N N   . MET A 1 671 ? 146.157 154.603 107.854 1.00 120.91 ? 672 MET A N   1 
ATOM   5001 C CA  . MET A 1 671 ? 144.809 154.647 108.401 1.00 116.52 ? 672 MET A CA  1 
ATOM   5002 C C   . MET A 1 671 ? 143.811 154.295 107.309 1.00 114.47 ? 672 MET A C   1 
ATOM   5003 O O   . MET A 1 671 ? 143.942 154.740 106.165 1.00 114.62 ? 672 MET A O   1 
ATOM   5004 C CB  . MET A 1 671 ? 144.481 156.036 108.965 1.00 114.91 ? 672 MET A CB  1 
ATOM   5005 C CG  . MET A 1 671 ? 143.675 156.032 110.250 1.00 120.80 ? 672 MET A CG  1 
ATOM   5006 S SD  . MET A 1 671 ? 144.419 155.119 111.612 1.00 128.96 ? 672 MET A SD  1 
ATOM   5007 C CE  . MET A 1 671 ? 146.060 155.838 111.680 1.00 123.92 ? 672 MET A CE  1 
ATOM   5008 N N   . ARG A 1 672 ? 142.810 153.489 107.660 1.00 110.04 ? 673 ARG A N   1 
ATOM   5009 C CA  . ARG A 1 672 ? 141.771 153.126 106.703 1.00 105.38 ? 673 ARG A CA  1 
ATOM   5010 C C   . ARG A 1 672 ? 140.399 153.428 107.286 1.00 108.40 ? 673 ARG A C   1 
ATOM   5011 O O   . ARG A 1 672 ? 140.231 153.568 108.498 1.00 109.63 ? 673 ARG A O   1 
ATOM   5012 C CB  . ARG A 1 672 ? 141.840 151.647 106.281 1.00 108.66 ? 673 ARG A CB  1 
ATOM   5013 C CG  . ARG A 1 672 ? 142.866 151.317 105.193 1.00 117.08 ? 673 ARG A CG  1 
ATOM   5014 C CD  . ARG A 1 672 ? 144.306 151.269 105.681 1.00 117.61 ? 673 ARG A CD  1 
ATOM   5015 N NE  . ARG A 1 672 ? 145.221 150.919 104.603 1.00 110.94 ? 673 ARG A NE  1 
ATOM   5016 C CZ  . ARG A 1 672 ? 145.534 149.677 104.269 1.00 108.83 ? 673 ARG A CZ  1 
ATOM   5017 N NH1 . ARG A 1 672 ? 145.024 148.641 104.913 1.00 109.13 ? 673 ARG A NH1 1 
ATOM   5018 N NH2 . ARG A 1 672 ? 146.374 149.468 103.261 1.00 113.81 ? 673 ARG A NH2 1 
ATOM   5019 N N   . TRP A 1 673 ? 139.412 153.519 106.398 1.00 108.23 ? 674 TRP A N   1 
ATOM   5020 C CA  . TRP A 1 673 ? 138.028 153.777 106.769 1.00 113.13 ? 674 TRP A CA  1 
ATOM   5021 C C   . TRP A 1 673 ? 137.148 152.632 106.289 1.00 106.29 ? 674 TRP A C   1 
ATOM   5022 O O   . TRP A 1 673 ? 137.374 152.071 105.213 1.00 104.87 ? 674 TRP A O   1 
ATOM   5023 C CB  . TRP A 1 673 ? 137.539 155.098 106.175 1.00 116.45 ? 674 TRP A CB  1 
ATOM   5024 C CG  . TRP A 1 673 ? 137.981 156.301 106.947 1.00 113.24 ? 674 TRP A CG  1 
ATOM   5025 C CD1 . TRP A 1 673 ? 139.024 157.121 106.648 1.00 112.99 ? 674 TRP A CD1 1 
ATOM   5026 C CD2 . TRP A 1 673 ? 137.382 156.832 108.135 1.00 111.51 ? 674 TRP A CD2 1 
ATOM   5027 N NE1 . TRP A 1 673 ? 139.123 158.124 107.579 1.00 115.76 ? 674 TRP A NE1 1 
ATOM   5028 C CE2 . TRP A 1 673 ? 138.124 157.970 108.502 1.00 112.58 ? 674 TRP A CE2 1 
ATOM   5029 C CE3 . TRP A 1 673 ? 136.292 156.455 108.924 1.00 113.10 ? 674 TRP A CE3 1 
ATOM   5030 C CZ2 . TRP A 1 673 ? 137.813 158.733 109.621 1.00 113.63 ? 674 TRP A CZ2 1 
ATOM   5031 C CZ3 . TRP A 1 673 ? 135.987 157.212 110.038 1.00 117.03 ? 674 TRP A CZ3 1 
ATOM   5032 C CH2 . TRP A 1 673 ? 136.745 158.338 110.377 1.00 117.36 ? 674 TRP A CH2 1 
ATOM   5033 N N   . TYR A 1 674 ? 136.143 152.291 107.092 1.00 104.05 ? 675 TYR A N   1 
ATOM   5034 C CA  . TYR A 1 674 ? 135.255 151.174 106.815 1.00 102.34 ? 675 TYR A CA  1 
ATOM   5035 C C   . TYR A 1 674 ? 133.812 151.611 107.020 1.00 99.92  ? 675 TYR A C   1 
ATOM   5036 O O   . TYR A 1 674 ? 133.524 152.449 107.877 1.00 107.50 ? 675 TYR A O   1 
ATOM   5037 C CB  . TYR A 1 674 ? 135.569 149.980 107.728 1.00 106.88 ? 675 TYR A CB  1 
ATOM   5038 C CG  . TYR A 1 674 ? 136.677 149.082 107.228 1.00 102.87 ? 675 TYR A CG  1 
ATOM   5039 C CD1 . TYR A 1 674 ? 138.005 149.350 107.538 1.00 97.66  ? 675 TYR A CD1 1 
ATOM   5040 C CD2 . TYR A 1 674 ? 136.396 147.952 106.470 1.00 100.08 ? 675 TYR A CD2 1 
ATOM   5041 C CE1 . TYR A 1 674 ? 139.023 148.531 107.089 1.00 99.77  ? 675 TYR A CE1 1 
ATOM   5042 C CE2 . TYR A 1 674 ? 137.408 147.125 106.017 1.00 93.06  ? 675 TYR A CE2 1 
ATOM   5043 C CZ  . TYR A 1 674 ? 138.718 147.420 106.331 1.00 100.07 ? 675 TYR A CZ  1 
ATOM   5044 O OH  . TYR A 1 674 ? 139.728 146.601 105.885 1.00 101.38 ? 675 TYR A OH  1 
ATOM   5045 N N   . ARG A 1 675 ? 132.903 151.026 106.242 1.00 100.54 ? 676 ARG A N   1 
ATOM   5046 C CA  . ARG A 1 675 ? 131.482 151.325 106.346 1.00 104.46 ? 676 ARG A CA  1 
ATOM   5047 C C   . ARG A 1 675 ? 130.697 150.077 106.723 1.00 109.98 ? 676 ARG A C   1 
ATOM   5048 O O   . ARG A 1 675 ? 131.109 148.949 106.440 1.00 117.06 ? 676 ARG A O   1 
ATOM   5049 C CB  . ARG A 1 675 ? 130.923 151.906 105.040 1.00 106.08 ? 676 ARG A CB  1 
ATOM   5050 C CG  . ARG A 1 675 ? 130.978 150.972 103.848 1.00 111.40 ? 676 ARG A CG  1 
ATOM   5051 C CD  . ARG A 1 675 ? 130.433 151.644 102.604 1.00 118.59 ? 676 ARG A CD  1 
ATOM   5052 N NE  . ARG A 1 675 ? 129.004 151.909 102.717 1.00 126.11 ? 676 ARG A NE  1 
ATOM   5053 C CZ  . ARG A 1 675 ? 128.328 152.723 101.918 1.00 137.17 ? 676 ARG A CZ  1 
ATOM   5054 N NH1 . ARG A 1 675 ? 128.920 153.366 100.926 1.00 140.29 ? 676 ARG A NH1 1 
ATOM   5055 N NH2 . ARG A 1 675 ? 127.025 152.894 102.119 1.00 142.41 ? 676 ARG A NH2 1 
ATOM   5056 N N   . GLN A 1 676 ? 129.560 150.298 107.379 1.00 110.84 ? 677 GLN A N   1 
ATOM   5057 C CA  . GLN A 1 676 ? 128.662 149.229 107.813 1.00 110.77 ? 677 GLN A CA  1 
ATOM   5058 C C   . GLN A 1 676 ? 127.241 149.710 107.544 1.00 109.94 ? 677 GLN A C   1 
ATOM   5059 O O   . GLN A 1 676 ? 126.696 150.499 108.319 1.00 116.58 ? 677 GLN A O   1 
ATOM   5060 C CB  . GLN A 1 676 ? 128.875 148.898 109.288 1.00 110.41 ? 677 GLN A CB  1 
ATOM   5061 C CG  . GLN A 1 676 ? 128.300 147.564 109.772 1.00 111.41 ? 677 GLN A CG  1 
ATOM   5062 C CD  . GLN A 1 676 ? 126.810 147.598 110.034 1.00 115.78 ? 677 GLN A CD  1 
ATOM   5063 O OE1 . GLN A 1 676 ? 126.281 148.582 110.547 1.00 121.14 ? 677 GLN A OE1 1 
ATOM   5064 N NE2 . GLN A 1 676 ? 126.124 146.517 109.683 1.00 119.17 ? 677 GLN A NE2 1 
ATOM   5065 N N   . ALA A 1 677 ? 126.672 149.277 106.431 1.00 112.13 ? 678 ALA A N   1 
ATOM   5066 C CA  . ALA A 1 677 ? 125.252 149.487 106.230 1.00 115.31 ? 678 ALA A CA  1 
ATOM   5067 C C   . ALA A 1 677 ? 124.471 148.576 107.175 1.00 121.66 ? 678 ALA A C   1 
ATOM   5068 O O   . ALA A 1 677 ? 124.948 147.492 107.522 1.00 126.07 ? 678 ALA A O   1 
ATOM   5069 C CB  . ALA A 1 677 ? 124.867 149.200 104.783 1.00 114.62 ? 678 ALA A CB  1 
ATOM   5070 N N   . PRO A 1 678 ? 123.296 149.011 107.637 1.00 122.55 ? 679 PRO A N   1 
ATOM   5071 C CA  . PRO A 1 678 ? 122.505 148.173 108.550 1.00 117.31 ? 679 PRO A CA  1 
ATOM   5072 C C   . PRO A 1 678 ? 122.028 146.893 107.879 1.00 121.26 ? 679 PRO A C   1 
ATOM   5073 O O   . PRO A 1 678 ? 121.321 146.923 106.869 1.00 119.73 ? 679 PRO A O   1 
ATOM   5074 C CB  . PRO A 1 678 ? 121.332 149.081 108.931 1.00 117.74 ? 679 PRO A CB  1 
ATOM   5075 C CG  . PRO A 1 678 ? 121.865 150.456 108.776 1.00 123.91 ? 679 PRO A CG  1 
ATOM   5076 C CD  . PRO A 1 678 ? 122.796 150.397 107.599 1.00 127.16 ? 679 PRO A CD  1 
ATOM   5077 N N   . GLY A 1 679 ? 122.431 145.761 108.455 1.00 122.27 ? 680 GLY A N   1 
ATOM   5078 C CA  . GLY A 1 679 ? 122.137 144.459 107.902 1.00 118.53 ? 680 GLY A CA  1 
ATOM   5079 C C   . GLY A 1 679 ? 123.130 143.953 106.880 1.00 122.55 ? 680 GLY A C   1 
ATOM   5080 O O   . GLY A 1 679 ? 122.968 142.827 106.393 1.00 128.14 ? 680 GLY A O   1 
ATOM   5081 N N   . LYS A 1 680 ? 124.150 144.734 106.540 1.00 121.32 ? 681 LYS A N   1 
ATOM   5082 C CA  . LYS A 1 680 ? 125.109 144.370 105.510 1.00 122.29 ? 681 LYS A CA  1 
ATOM   5083 C C   . LYS A 1 680 ? 126.483 144.107 106.111 1.00 122.25 ? 681 LYS A C   1 
ATOM   5084 O O   . LYS A 1 680 ? 126.779 144.487 107.247 1.00 122.65 ? 681 LYS A O   1 
ATOM   5085 C CB  . LYS A 1 680 ? 125.211 145.467 104.445 1.00 117.20 ? 681 LYS A CB  1 
ATOM   5086 C CG  . LYS A 1 680 ? 123.921 145.716 103.689 1.00 111.73 ? 681 LYS A CG  1 
ATOM   5087 C CD  . LYS A 1 680 ? 123.577 144.538 102.798 1.00 114.52 ? 681 LYS A CD  1 
ATOM   5088 C CE  . LYS A 1 680 ? 122.284 144.778 102.042 1.00 124.47 ? 681 LYS A CE  1 
ATOM   5089 N NZ  . LYS A 1 680 ? 122.429 145.863 101.033 1.00 127.13 ? 681 LYS A NZ  1 
ATOM   5090 N N   . GLU A 1 681 ? 127.320 143.437 105.323 1.00 118.46 ? 682 GLU A N   1 
ATOM   5091 C CA  . GLU A 1 681 ? 128.686 143.145 105.726 1.00 118.87 ? 682 GLU A CA  1 
ATOM   5092 C C   . GLU A 1 681 ? 129.532 144.416 105.667 1.00 124.18 ? 682 GLU A C   1 
ATOM   5093 O O   . GLU A 1 681 ? 129.298 145.304 104.843 1.00 125.02 ? 682 GLU A O   1 
ATOM   5094 C CB  . GLU A 1 681 ? 129.266 142.049 104.822 1.00 122.48 ? 682 GLU A CB  1 
ATOM   5095 C CG  . GLU A 1 681 ? 130.682 141.562 105.145 1.00 132.82 ? 682 GLU A CG  1 
ATOM   5096 C CD  . GLU A 1 681 ? 130.785 140.847 106.484 1.00 141.32 ? 682 GLU A CD  1 
ATOM   5097 O OE1 . GLU A 1 681 ? 129.774 140.275 106.945 1.00 144.79 ? 682 GLU A OE1 1 
ATOM   5098 O OE2 . GLU A 1 681 ? 131.883 140.862 107.079 1.00 138.51 ? 682 GLU A OE2 1 
ATOM   5099 N N   . ARG A 1 682 ? 130.501 144.508 106.579 1.00 123.10 ? 683 ARG A N   1 
ATOM   5100 C CA  . ARG A 1 682 ? 131.400 145.655 106.634 1.00 114.77 ? 683 ARG A CA  1 
ATOM   5101 C C   . ARG A 1 682 ? 132.281 145.737 105.391 1.00 114.89 ? 683 ARG A C   1 
ATOM   5102 O O   . ARG A 1 682 ? 132.828 144.734 104.925 1.00 122.38 ? 683 ARG A O   1 
ATOM   5103 C CB  . ARG A 1 682 ? 132.254 145.572 107.898 1.00 111.50 ? 683 ARG A CB  1 
ATOM   5104 C CG  . ARG A 1 682 ? 131.665 146.363 109.040 1.00 105.28 ? 683 ARG A CG  1 
ATOM   5105 C CD  . ARG A 1 682 ? 132.670 146.725 110.105 1.00 110.62 ? 683 ARG A CD  1 
ATOM   5106 N NE  . ARG A 1 682 ? 132.912 145.583 110.977 1.00 112.82 ? 683 ARG A NE  1 
ATOM   5107 C CZ  . ARG A 1 682 ? 132.576 145.542 112.258 1.00 115.07 ? 683 ARG A CZ  1 
ATOM   5108 N NH1 . ARG A 1 682 ? 132.006 146.575 112.856 1.00 120.51 ? 683 ARG A NH1 1 
ATOM   5109 N NH2 . ARG A 1 682 ? 132.810 144.435 112.956 1.00 116.12 ? 683 ARG A NH2 1 
ATOM   5110 N N   . GLU A 1 683 ? 132.414 146.950 104.860 1.00 107.95 ? 684 GLU A N   1 
ATOM   5111 C CA  . GLU A 1 683 ? 133.078 147.199 103.590 1.00 105.75 ? 684 GLU A CA  1 
ATOM   5112 C C   . GLU A 1 683 ? 134.042 148.369 103.753 1.00 106.18 ? 684 GLU A C   1 
ATOM   5113 O O   . GLU A 1 683 ? 133.781 149.311 104.502 1.00 112.04 ? 684 GLU A O   1 
ATOM   5114 C CB  . GLU A 1 683 ? 132.041 147.486 102.488 1.00 111.19 ? 684 GLU A CB  1 
ATOM   5115 C CG  . GLU A 1 683 ? 132.589 147.660 101.081 1.00 116.59 ? 684 GLU A CG  1 
ATOM   5116 C CD  . GLU A 1 683 ? 131.498 147.900 100.058 1.00 128.37 ? 684 GLU A CD  1 
ATOM   5117 O OE1 . GLU A 1 683 ? 130.314 147.954 100.452 1.00 136.50 ? 684 GLU A OE1 1 
ATOM   5118 O OE2 . GLU A 1 683 ? 131.823 148.035 98.860  1.00 127.12 ? 684 GLU A OE2 1 
ATOM   5119 N N   . TRP A 1 684 ? 135.163 148.298 103.043 1.00 102.84 ? 685 TRP A N   1 
ATOM   5120 C CA  . TRP A 1 684 ? 136.215 149.302 103.096 1.00 97.97  ? 685 TRP A CA  1 
ATOM   5121 C C   . TRP A 1 684 ? 135.840 150.526 102.263 1.00 104.78 ? 685 TRP A C   1 
ATOM   5122 O O   . TRP A 1 684 ? 135.201 150.412 101.213 1.00 114.18 ? 685 TRP A O   1 
ATOM   5123 C CB  . TRP A 1 684 ? 137.532 148.688 102.612 1.00 102.22 ? 685 TRP A CB  1 
ATOM   5124 C CG  . TRP A 1 684 ? 138.595 149.657 102.232 1.00 104.35 ? 685 TRP A CG  1 
ATOM   5125 C CD1 . TRP A 1 684 ? 139.489 150.259 103.065 1.00 100.87 ? 685 TRP A CD1 1 
ATOM   5126 C CD2 . TRP A 1 684 ? 138.899 150.118 100.913 1.00 104.58 ? 685 TRP A CD2 1 
ATOM   5127 N NE1 . TRP A 1 684 ? 140.324 151.078 102.348 1.00 102.65 ? 685 TRP A NE1 1 
ATOM   5128 C CE2 . TRP A 1 684 ? 139.981 151.010 101.023 1.00 106.57 ? 685 TRP A CE2 1 
ATOM   5129 C CE3 . TRP A 1 684 ? 138.355 149.871 99.650  1.00 101.40 ? 685 TRP A CE3 1 
ATOM   5130 C CZ2 . TRP A 1 684 ? 140.530 151.653 99.919  1.00 112.45 ? 685 TRP A CZ2 1 
ATOM   5131 C CZ3 . TRP A 1 684 ? 138.900 150.508 98.558  1.00 106.31 ? 685 TRP A CZ3 1 
ATOM   5132 C CH2 . TRP A 1 684 ? 139.977 151.389 98.698  1.00 111.75 ? 685 TRP A CH2 1 
ATOM   5133 N N   . VAL A 1 685 ? 136.237 151.705 102.747 1.00 107.82 ? 686 VAL A N   1 
ATOM   5134 C CA  . VAL A 1 685 ? 135.893 152.983 102.121 1.00 103.16 ? 686 VAL A CA  1 
ATOM   5135 C C   . VAL A 1 685 ? 137.099 153.610 101.427 1.00 107.65 ? 686 VAL A C   1 
ATOM   5136 O O   . VAL A 1 685 ? 137.091 153.810 100.211 1.00 111.15 ? 686 VAL A O   1 
ATOM   5137 C CB  . VAL A 1 685 ? 135.278 153.957 103.150 1.00 107.44 ? 686 VAL A CB  1 
ATOM   5138 C CG1 . VAL A 1 685 ? 135.030 155.316 102.514 1.00 115.35 ? 686 VAL A CG1 1 
ATOM   5139 C CG2 . VAL A 1 685 ? 134.000 153.393 103.707 1.00 113.18 ? 686 VAL A CG2 1 
ATOM   5140 N N   . ALA A 1 686 ? 138.143 153.936 102.186 1.00 115.40 ? 687 ALA A N   1 
ATOM   5141 C CA  . ALA A 1 686 ? 139.280 154.663 101.640 1.00 117.50 ? 687 ALA A CA  1 
ATOM   5142 C C   . ALA A 1 686 ? 140.532 154.296 102.420 1.00 112.56 ? 687 ALA A C   1 
ATOM   5143 O O   . ALA A 1 686 ? 140.461 153.784 103.540 1.00 112.66 ? 687 ALA A O   1 
ATOM   5144 C CB  . ALA A 1 686 ? 139.049 156.177 101.679 1.00 119.32 ? 687 ALA A CB  1 
ATOM   5145 N N   . GLY A 1 687 ? 141.677 154.565 101.813 1.00 104.00 ? 688 GLY A N   1 
ATOM   5146 C CA  . GLY A 1 687 ? 142.950 154.255 102.438 1.00 104.56 ? 688 GLY A CA  1 
ATOM   5147 C C   . GLY A 1 687 ? 144.027 155.215 101.993 1.00 109.76 ? 688 GLY A C   1 
ATOM   5148 O O   . GLY A 1 687 ? 144.005 155.727 100.869 1.00 113.74 ? 688 GLY A O   1 
ATOM   5149 N N   . MET A 1 688 ? 144.982 155.453 102.887 1.00 112.45 ? 689 MET A N   1 
ATOM   5150 C CA  . MET A 1 688 ? 146.130 156.306 102.627 1.00 112.88 ? 689 MET A CA  1 
ATOM   5151 C C   . MET A 1 688 ? 147.395 155.518 102.932 1.00 114.07 ? 689 MET A C   1 
ATOM   5152 O O   . MET A 1 688 ? 147.430 154.718 103.869 1.00 115.21 ? 689 MET A O   1 
ATOM   5153 C CB  . MET A 1 688 ? 146.075 157.590 103.481 1.00 118.12 ? 689 MET A CB  1 
ATOM   5154 C CG  . MET A 1 688 ? 147.168 158.607 103.190 1.00 120.47 ? 689 MET A CG  1 
ATOM   5155 S SD  . MET A 1 688 ? 147.072 160.081 104.221 1.00 141.28 ? 689 MET A SD  1 
ATOM   5156 C CE  . MET A 1 688 ? 145.644 160.898 103.529 1.00 112.66 ? 689 MET A CE  1 
ATOM   5157 N N   . SER A 1 689 ? 148.432 155.737 102.125 1.00 113.28 ? 690 SER A N   1 
ATOM   5158 C CA  . SER A 1 689 ? 149.689 155.032 102.309 1.00 112.66 ? 690 SER A CA  1 
ATOM   5159 C C   . SER A 1 689 ? 150.429 155.554 103.541 1.00 114.60 ? 690 SER A C   1 
ATOM   5160 O O   . SER A 1 689 ? 150.087 156.587 104.123 1.00 119.84 ? 690 SER A O   1 
ATOM   5161 C CB  . SER A 1 689 ? 150.565 155.170 101.065 1.00 117.04 ? 690 SER A CB  1 
ATOM   5162 O OG  . SER A 1 689 ? 150.736 156.531 100.711 1.00 116.03 ? 690 SER A OG  1 
ATOM   5163 N N   . SER A 1 690 ? 151.467 154.814 103.938 1.00 114.70 ? 691 SER A N   1 
ATOM   5164 C CA  . SER A 1 690 ? 152.263 155.181 105.103 1.00 111.79 ? 691 SER A CA  1 
ATOM   5165 C C   . SER A 1 690 ? 153.206 156.345 104.836 1.00 111.32 ? 691 SER A C   1 
ATOM   5166 O O   . SER A 1 690 ? 153.697 156.957 105.790 1.00 106.88 ? 691 SER A O   1 
ATOM   5167 C CB  . SER A 1 690 ? 153.068 153.975 105.586 1.00 112.12 ? 691 SER A CB  1 
ATOM   5168 O OG  . SER A 1 690 ? 153.833 153.422 104.531 1.00 119.99 ? 691 SER A OG  1 
ATOM   5169 N N   . ALA A 1 691 ? 153.477 156.659 103.571 1.00 116.27 ? 692 ALA A N   1 
ATOM   5170 C CA  . ALA A 1 691 ? 154.326 157.787 103.219 1.00 110.75 ? 692 ALA A CA  1 
ATOM   5171 C C   . ALA A 1 691 ? 153.546 159.070 102.974 1.00 109.45 ? 692 ALA A C   1 
ATOM   5172 O O   . ALA A 1 691 ? 154.163 160.125 102.795 1.00 114.11 ? 692 ALA A O   1 
ATOM   5173 C CB  . ALA A 1 691 ? 155.157 157.455 101.977 1.00 113.41 ? 692 ALA A CB  1 
ATOM   5174 N N   . GLY A 1 692 ? 152.216 159.011 102.965 1.00 107.38 ? 693 GLY A N   1 
ATOM   5175 C CA  . GLY A 1 692 ? 151.420 160.197 102.721 1.00 108.81 ? 693 GLY A CA  1 
ATOM   5176 C C   . GLY A 1 692 ? 151.424 160.684 101.292 1.00 121.17 ? 693 GLY A C   1 
ATOM   5177 O O   . GLY A 1 692 ? 151.154 161.862 101.049 1.00 124.49 ? 693 GLY A O   1 
ATOM   5178 N N   . ASP A 1 693 ? 151.726 159.810 100.333 1.00 126.10 ? 694 ASP A N   1 
ATOM   5179 C CA  . ASP A 1 693 ? 151.768 160.182 98.927  1.00 127.16 ? 694 ASP A CA  1 
ATOM   5180 C C   . ASP A 1 693 ? 150.740 159.456 98.076  1.00 128.49 ? 694 ASP A C   1 
ATOM   5181 O O   . ASP A 1 693 ? 150.203 160.051 97.140  1.00 137.67 ? 694 ASP A O   1 
ATOM   5182 C CB  . ASP A 1 693 ? 153.168 159.920 98.352  1.00 135.35 ? 694 ASP A CB  1 
ATOM   5183 C CG  . ASP A 1 693 ? 153.319 160.409 96.921  1.00 147.02 ? 694 ASP A CG  1 
ATOM   5184 O OD1 . ASP A 1 693 ? 153.706 161.581 96.733  1.00 152.45 ? 694 ASP A OD1 1 
ATOM   5185 O OD2 . ASP A 1 693 ? 153.064 159.621 95.986  1.00 145.32 ? 694 ASP A OD2 1 
ATOM   5186 N N   . ARG A 1 694 ? 150.445 158.197 98.382  1.00 122.96 ? 695 ARG A N   1 
ATOM   5187 C CA  . ARG A 1 694 ? 149.501 157.400 97.615  1.00 124.60 ? 695 ARG A CA  1 
ATOM   5188 C C   . ARG A 1 694 ? 148.219 157.203 98.413  1.00 123.94 ? 695 ARG A C   1 
ATOM   5189 O O   . ARG A 1 694 ? 148.239 157.128 99.644  1.00 128.89 ? 695 ARG A O   1 
ATOM   5190 C CB  . ARG A 1 694 ? 150.077 156.026 97.226  1.00 131.36 ? 695 ARG A CB  1 
ATOM   5191 C CG  . ARG A 1 694 ? 151.232 156.009 96.202  1.00 134.41 ? 695 ARG A CG  1 
ATOM   5192 C CD  . ARG A 1 694 ? 152.609 156.353 96.778  1.00 137.54 ? 695 ARG A CD  1 
ATOM   5193 N NE  . ARG A 1 694 ? 152.872 155.680 98.045  1.00 146.87 ? 695 ARG A NE  1 
ATOM   5194 C CZ  . ARG A 1 694 ? 153.238 154.411 98.168  1.00 151.25 ? 695 ARG A CZ  1 
ATOM   5195 N NH1 . ARG A 1 694 ? 153.422 153.637 97.111  1.00 148.78 ? 695 ARG A NH1 1 
ATOM   5196 N NH2 . ARG A 1 694 ? 153.435 153.908 99.383  1.00 149.32 ? 695 ARG A NH2 1 
ATOM   5197 N N   . SER A 1 695 ? 147.099 157.128 97.697  1.00 116.04 ? 696 SER A N   1 
ATOM   5198 C CA  . SER A 1 695 ? 145.798 156.954 98.326  1.00 116.28 ? 696 SER A CA  1 
ATOM   5199 C C   . SER A 1 695 ? 144.894 156.167 97.391  1.00 111.09 ? 696 SER A C   1 
ATOM   5200 O O   . SER A 1 695 ? 145.133 156.088 96.184  1.00 120.59 ? 696 SER A O   1 
ATOM   5201 C CB  . SER A 1 695 ? 145.158 158.301 98.680  1.00 121.89 ? 696 SER A CB  1 
ATOM   5202 O OG  . SER A 1 695 ? 145.924 158.996 99.648  1.00 123.26 ? 696 SER A OG  1 
ATOM   5203 N N   . SER A 1 696 ? 143.846 155.583 97.966  1.00 106.52 ? 697 SER A N   1 
ATOM   5204 C CA  . SER A 1 696 ? 142.884 154.817 97.189  1.00 110.42 ? 697 SER A CA  1 
ATOM   5205 C C   . SER A 1 696 ? 141.504 154.978 97.803  1.00 112.99 ? 697 SER A C   1 
ATOM   5206 O O   . SER A 1 696 ? 141.367 155.223 99.004  1.00 112.98 ? 697 SER A O   1 
ATOM   5207 C CB  . SER A 1 696 ? 143.257 153.332 97.125  1.00 115.10 ? 697 SER A CB  1 
ATOM   5208 O OG  . SER A 1 696 ? 143.225 152.748 98.413  1.00 118.35 ? 697 SER A OG  1 
ATOM   5209 N N   . TYR A 1 697 ? 140.483 154.819 96.969  1.00 113.21 ? 698 TYR A N   1 
ATOM   5210 C CA  . TYR A 1 697 ? 139.102 154.997 97.384  1.00 116.45 ? 698 TYR A CA  1 
ATOM   5211 C C   . TYR A 1 697 ? 138.289 153.816 96.878  1.00 125.22 ? 698 TYR A C   1 
ATOM   5212 O O   . TYR A 1 697 ? 138.750 153.034 96.043  1.00 128.55 ? 698 TYR A O   1 
ATOM   5213 C CB  . TYR A 1 697 ? 138.517 156.305 96.835  1.00 116.58 ? 698 TYR A CB  1 
ATOM   5214 C CG  . TYR A 1 697 ? 139.212 157.549 97.337  1.00 119.03 ? 698 TYR A CG  1 
ATOM   5215 C CD1 . TYR A 1 697 ? 138.922 158.086 98.583  1.00 121.37 ? 698 TYR A CD1 1 
ATOM   5216 C CD2 . TYR A 1 697 ? 140.170 158.183 96.555  1.00 124.08 ? 698 TYR A CD2 1 
ATOM   5217 C CE1 . TYR A 1 697 ? 139.568 159.225 99.035  1.00 122.47 ? 698 TYR A CE1 1 
ATOM   5218 C CE2 . TYR A 1 697 ? 140.820 159.318 96.997  1.00 116.77 ? 698 TYR A CE2 1 
ATOM   5219 C CZ  . TYR A 1 697 ? 140.516 159.834 98.235  1.00 115.05 ? 698 TYR A CZ  1 
ATOM   5220 O OH  . TYR A 1 697 ? 141.167 160.965 98.666  1.00 113.81 ? 698 TYR A OH  1 
ATOM   5221 N N   . GLU A 1 698 ? 137.075 153.682 97.405  1.00 122.37 ? 699 GLU A N   1 
ATOM   5222 C CA  . GLU A 1 698 ? 136.140 152.707 96.864  1.00 117.21 ? 699 GLU A CA  1 
ATOM   5223 C C   . GLU A 1 698 ? 135.691 153.152 95.475  1.00 123.78 ? 699 GLU A C   1 
ATOM   5224 O O   . GLU A 1 698 ? 135.575 154.347 95.193  1.00 128.27 ? 699 GLU A O   1 
ATOM   5225 C CB  . GLU A 1 698 ? 134.942 152.545 97.803  1.00 120.59 ? 699 GLU A CB  1 
ATOM   5226 C CG  . GLU A 1 698 ? 134.024 151.375 97.489  1.00 127.51 ? 699 GLU A CG  1 
ATOM   5227 C CD  . GLU A 1 698 ? 134.786 150.102 97.182  1.00 130.31 ? 699 GLU A CD  1 
ATOM   5228 O OE1 . GLU A 1 698 ? 135.363 149.513 98.120  1.00 131.07 ? 699 GLU A OE1 1 
ATOM   5229 O OE2 . GLU A 1 698 ? 134.807 149.689 96.003  1.00 130.62 ? 699 GLU A OE2 1 
ATOM   5230 N N   . ASP A 1 699 ? 135.464 152.172 94.594  1.00 125.58 ? 700 ASP A N   1 
ATOM   5231 C CA  . ASP A 1 699 ? 135.155 152.477 93.199  1.00 128.96 ? 700 ASP A CA  1 
ATOM   5232 C C   . ASP A 1 699 ? 133.779 153.112 93.037  1.00 125.05 ? 700 ASP A C   1 
ATOM   5233 O O   . ASP A 1 699 ? 133.542 153.829 92.059  1.00 123.77 ? 700 ASP A O   1 
ATOM   5234 C CB  . ASP A 1 699 ? 135.252 151.208 92.353  1.00 134.73 ? 700 ASP A CB  1 
ATOM   5235 C CG  . ASP A 1 699 ? 136.642 150.603 92.367  1.00 137.37 ? 700 ASP A CG  1 
ATOM   5236 O OD1 . ASP A 1 699 ? 137.576 151.268 92.862  1.00 131.76 ? 700 ASP A OD1 1 
ATOM   5237 O OD2 . ASP A 1 699 ? 136.800 149.462 91.883  1.00 145.29 ? 700 ASP A OD2 1 
ATOM   5238 N N   . SER A 1 700 ? 132.862 152.861 93.971  1.00 127.62 ? 701 SER A N   1 
ATOM   5239 C CA  . SER A 1 700 ? 131.538 153.467 93.877  1.00 132.47 ? 701 SER A CA  1 
ATOM   5240 C C   . SER A 1 700 ? 131.571 154.940 94.269  1.00 130.40 ? 701 SER A C   1 
ATOM   5241 O O   . SER A 1 700 ? 130.816 155.751 93.721  1.00 130.66 ? 701 SER A O   1 
ATOM   5242 C CB  . SER A 1 700 ? 130.545 152.701 94.752  1.00 135.90 ? 701 SER A CB  1 
ATOM   5243 O OG  . SER A 1 700 ? 130.997 152.625 96.093  1.00 133.33 ? 701 SER A OG  1 
ATOM   5244 N N   . VAL A 1 701 ? 132.436 155.304 95.212  1.00 129.39 ? 702 VAL A N   1 
ATOM   5245 C CA  . VAL A 1 701 ? 132.507 156.661 95.736  1.00 127.59 ? 702 VAL A CA  1 
ATOM   5246 C C   . VAL A 1 701 ? 133.824 157.347 95.361  1.00 129.94 ? 702 VAL A C   1 
ATOM   5247 O O   . VAL A 1 701 ? 134.262 158.274 96.042  1.00 125.75 ? 702 VAL A O   1 
ATOM   5248 C CB  . VAL A 1 701 ? 132.261 156.674 97.259  1.00 124.82 ? 702 VAL A CB  1 
ATOM   5249 C CG1 . VAL A 1 701 ? 130.907 156.068 97.573  1.00 122.29 ? 702 VAL A CG1 1 
ATOM   5250 C CG2 . VAL A 1 701 ? 133.332 155.875 97.988  1.00 128.13 ? 702 VAL A CG2 1 
ATOM   5251 N N   . LYS A 1 702 ? 134.445 156.913 94.264  1.00 136.08 ? 703 LYS A N   1 
ATOM   5252 C CA  . LYS A 1 702 ? 135.672 157.538 93.779  1.00 135.86 ? 703 LYS A CA  1 
ATOM   5253 C C   . LYS A 1 702 ? 135.404 158.961 93.303  1.00 137.64 ? 703 LYS A C   1 
ATOM   5254 O O   . LYS A 1 702 ? 134.491 159.204 92.509  1.00 137.13 ? 703 LYS A O   1 
ATOM   5255 C CB  . LYS A 1 702 ? 136.264 156.708 92.638  1.00 136.25 ? 703 LYS A CB  1 
ATOM   5256 C CG  . LYS A 1 702 ? 137.400 157.382 91.872  1.00 135.07 ? 703 LYS A CG  1 
ATOM   5257 C CD  . LYS A 1 702 ? 138.618 157.647 92.744  1.00 132.74 ? 703 LYS A CD  1 
ATOM   5258 C CE  . LYS A 1 702 ? 139.240 156.346 93.223  1.00 134.70 ? 703 LYS A CE  1 
ATOM   5259 N NZ  . LYS A 1 702 ? 139.741 155.515 92.093  1.00 132.54 ? 703 LYS A NZ  1 
ATOM   5260 N N   . GLY A 1 703 ? 136.204 159.903 93.799  1.00 141.80 ? 704 GLY A N   1 
ATOM   5261 C CA  . GLY A 1 703 ? 136.118 161.286 93.395  1.00 143.08 ? 704 GLY A CA  1 
ATOM   5262 C C   . GLY A 1 703 ? 135.130 162.127 94.176  1.00 139.79 ? 704 GLY A C   1 
ATOM   5263 O O   . GLY A 1 703 ? 135.095 163.347 93.986  1.00 140.20 ? 704 GLY A O   1 
ATOM   5264 N N   . ARG A 1 704 ? 134.330 161.519 95.050  1.00 134.49 ? 705 ARG A N   1 
ATOM   5265 C CA  . ARG A 1 704 ? 133.374 162.268 95.851  1.00 132.90 ? 705 ARG A CA  1 
ATOM   5266 C C   . ARG A 1 704 ? 133.743 162.323 97.327  1.00 136.74 ? 705 ARG A C   1 
ATOM   5267 O O   . ARG A 1 704 ? 133.155 163.122 98.064  1.00 139.47 ? 705 ARG A O   1 
ATOM   5268 C CB  . ARG A 1 704 ? 131.967 161.679 95.694  1.00 136.46 ? 705 ARG A CB  1 
ATOM   5269 C CG  . ARG A 1 704 ? 131.731 160.400 96.474  1.00 140.35 ? 705 ARG A CG  1 
ATOM   5270 C CD  . ARG A 1 704 ? 130.407 159.768 96.091  1.00 140.95 ? 705 ARG A CD  1 
ATOM   5271 N NE  . ARG A 1 704 ? 129.354 160.087 97.047  1.00 142.99 ? 705 ARG A NE  1 
ATOM   5272 C CZ  . ARG A 1 704 ? 128.078 159.769 96.884  1.00 147.06 ? 705 ARG A CZ  1 
ATOM   5273 N NH1 . ARG A 1 704 ? 127.662 159.109 95.817  1.00 148.55 ? 705 ARG A NH1 1 
ATOM   5274 N NH2 . ARG A 1 704 ? 127.199 160.122 97.817  1.00 146.82 ? 705 ARG A NH2 1 
ATOM   5275 N N   . PHE A 1 705 ? 134.688 161.503 97.777  1.00 133.20 ? 706 PHE A N   1 
ATOM   5276 C CA  . PHE A 1 705 ? 135.221 161.597 99.128  1.00 131.24 ? 706 PHE A CA  1 
ATOM   5277 C C   . PHE A 1 705 ? 136.650 162.120 99.066  1.00 126.94 ? 706 PHE A C   1 
ATOM   5278 O O   . PHE A 1 705 ? 137.273 162.163 98.002  1.00 124.79 ? 706 PHE A O   1 
ATOM   5279 C CB  . PHE A 1 705 ? 135.197 160.244 99.854  1.00 132.78 ? 706 PHE A CB  1 
ATOM   5280 C CG  . PHE A 1 705 ? 133.813 159.723 100.171 1.00 128.59 ? 706 PHE A CG  1 
ATOM   5281 C CD1 . PHE A 1 705 ? 132.690 160.533 100.075 1.00 129.40 ? 706 PHE A CD1 1 
ATOM   5282 C CD2 . PHE A 1 705 ? 133.650 158.414 100.599 1.00 132.01 ? 706 PHE A CD2 1 
ATOM   5283 C CE1 . PHE A 1 705 ? 131.430 160.037 100.364 1.00 135.78 ? 706 PHE A CE1 1 
ATOM   5284 C CE2 . PHE A 1 705 ? 132.395 157.915 100.901 1.00 138.84 ? 706 PHE A CE2 1 
ATOM   5285 C CZ  . PHE A 1 705 ? 131.285 158.729 100.786 1.00 140.44 ? 706 PHE A CZ  1 
ATOM   5286 N N   . THR A 1 706 ? 137.168 162.528 100.221 1.00 124.49 ? 707 THR A N   1 
ATOM   5287 C CA  . THR A 1 706 ? 138.530 163.048 100.291 1.00 123.44 ? 707 THR A CA  1 
ATOM   5288 C C   . THR A 1 706 ? 139.133 162.679 101.637 1.00 121.97 ? 707 THR A C   1 
ATOM   5289 O O   . THR A 1 706 ? 138.568 163.009 102.682 1.00 127.32 ? 707 THR A O   1 
ATOM   5290 C CB  . THR A 1 706 ? 138.555 164.567 100.091 1.00 129.42 ? 707 THR A CB  1 
ATOM   5291 O OG1 . THR A 1 706 ? 138.018 164.896 98.803  1.00 126.00 ? 707 THR A OG1 1 
ATOM   5292 C CG2 . THR A 1 706 ? 139.979 165.099 100.188 1.00 128.06 ? 707 THR A CG2 1 
ATOM   5293 N N   . ILE A 1 707 ? 140.269 162.006 101.612 1.00 117.09 ? 708 ILE A N   1 
ATOM   5294 C CA  . ILE A 1 707 ? 140.990 161.643 102.825 1.00 118.74 ? 708 ILE A CA  1 
ATOM   5295 C C   . ILE A 1 707 ? 142.061 162.694 103.100 1.00 118.87 ? 708 ILE A C   1 
ATOM   5296 O O   . ILE A 1 707 ? 142.664 163.259 102.179 1.00 122.17 ? 708 ILE A O   1 
ATOM   5297 C CB  . ILE A 1 707 ? 141.561 160.208 102.701 1.00 115.85 ? 708 ILE A CB  1 
ATOM   5298 C CG1 . ILE A 1 707 ? 142.108 159.701 104.038 1.00 118.57 ? 708 ILE A CG1 1 
ATOM   5299 C CG2 . ILE A 1 707 ? 142.576 160.083 101.564 1.00 118.25 ? 708 ILE A CG2 1 
ATOM   5300 C CD1 . ILE A 1 707 ? 141.060 159.539 105.095 1.00 118.20 ? 708 ILE A CD1 1 
ATOM   5301 N N   . SER A 1 708 ? 142.268 163.006 104.380 1.00 115.24 ? 709 SER A N   1 
ATOM   5302 C CA  . SER A 1 708 ? 143.267 163.990 104.777 1.00 113.10 ? 709 SER A CA  1 
ATOM   5303 C C   . SER A 1 708 ? 143.716 163.663 106.192 1.00 116.89 ? 709 SER A C   1 
ATOM   5304 O O   . SER A 1 708 ? 143.093 162.858 106.886 1.00 120.93 ? 709 SER A O   1 
ATOM   5305 C CB  . SER A 1 708 ? 142.713 165.415 104.693 1.00 112.44 ? 709 SER A CB  1 
ATOM   5306 O OG  . SER A 1 708 ? 141.549 165.553 105.490 1.00 110.65 ? 709 SER A OG  1 
ATOM   5307 N N   . ARG A 1 709 ? 144.801 164.301 106.622 1.00 116.16 ? 710 ARG A N   1 
ATOM   5308 C CA  . ARG A 1 709 ? 145.285 164.073 107.976 1.00 121.13 ? 710 ARG A CA  1 
ATOM   5309 C C   . ARG A 1 709 ? 146.064 165.283 108.466 1.00 129.07 ? 710 ARG A C   1 
ATOM   5310 O O   . ARG A 1 709 ? 146.496 166.135 107.686 1.00 119.52 ? 710 ARG A O   1 
ATOM   5311 C CB  . ARG A 1 709 ? 146.154 162.815 108.060 1.00 122.97 ? 710 ARG A CB  1 
ATOM   5312 C CG  . ARG A 1 709 ? 147.465 162.847 107.302 1.00 121.12 ? 710 ARG A CG  1 
ATOM   5313 C CD  . ARG A 1 709 ? 148.150 161.495 107.451 1.00 112.42 ? 710 ARG A CD  1 
ATOM   5314 N NE  . ARG A 1 709 ? 149.430 161.416 106.761 1.00 105.01 ? 710 ARG A NE  1 
ATOM   5315 C CZ  . ARG A 1 709 ? 150.204 160.340 106.755 1.00 113.95 ? 710 ARG A CZ  1 
ATOM   5316 N NH1 . ARG A 1 709 ? 149.845 159.228 107.374 1.00 116.32 ? 710 ARG A NH1 1 
ATOM   5317 N NH2 . ARG A 1 709 ? 151.365 160.380 106.110 1.00 119.33 ? 710 ARG A NH2 1 
ATOM   5318 N N   . ASP A 1 710 ? 146.227 165.341 109.787 1.00 139.83 ? 711 ASP A N   1 
ATOM   5319 C CA  . ASP A 1 710 ? 147.138 166.263 110.455 1.00 140.22 ? 711 ASP A CA  1 
ATOM   5320 C C   . ASP A 1 710 ? 148.068 165.409 111.306 1.00 132.00 ? 711 ASP A C   1 
ATOM   5321 O O   . ASP A 1 710 ? 147.632 164.801 112.294 1.00 129.40 ? 711 ASP A O   1 
ATOM   5322 C CB  . ASP A 1 710 ? 146.378 167.282 111.304 1.00 145.51 ? 711 ASP A CB  1 
ATOM   5323 C CG  . ASP A 1 710 ? 145.727 168.368 110.468 1.00 150.42 ? 711 ASP A CG  1 
ATOM   5324 O OD1 . ASP A 1 710 ? 146.125 168.541 109.297 1.00 144.71 ? 711 ASP A OD1 1 
ATOM   5325 O OD2 . ASP A 1 710 ? 144.814 169.048 110.983 1.00 154.22 ? 711 ASP A OD2 1 
ATOM   5326 N N   . ASP A 1 711 ? 149.340 165.344 110.900 1.00 131.24 ? 712 ASP A N   1 
ATOM   5327 C CA  . ASP A 1 711 ? 150.276 164.396 111.496 1.00 141.43 ? 712 ASP A CA  1 
ATOM   5328 C C   . ASP A 1 711 ? 150.710 164.838 112.888 1.00 142.97 ? 712 ASP A C   1 
ATOM   5329 O O   . ASP A 1 711 ? 150.770 164.023 113.817 1.00 138.58 ? 712 ASP A O   1 
ATOM   5330 C CB  . ASP A 1 711 ? 151.493 164.223 110.584 1.00 138.44 ? 712 ASP A CB  1 
ATOM   5331 C CG  . ASP A 1 711 ? 151.258 163.212 109.475 1.00 131.18 ? 712 ASP A CG  1 
ATOM   5332 O OD1 . ASP A 1 711 ? 150.578 162.195 109.723 1.00 128.69 ? 712 ASP A OD1 1 
ATOM   5333 O OD2 . ASP A 1 711 ? 151.758 163.433 108.352 1.00 126.48 ? 712 ASP A OD2 1 
ATOM   5334 N N   . ALA A 1 712 ? 151.022 166.127 113.050 1.00 146.13 ? 713 ALA A N   1 
ATOM   5335 C CA  . ALA A 1 712 ? 151.464 166.624 114.350 1.00 143.04 ? 713 ALA A CA  1 
ATOM   5336 C C   . ALA A 1 712 ? 150.303 166.703 115.332 1.00 143.33 ? 713 ALA A C   1 
ATOM   5337 O O   . ALA A 1 712 ? 150.501 166.617 116.550 1.00 141.10 ? 713 ALA A O   1 
ATOM   5338 C CB  . ALA A 1 712 ? 152.130 167.991 114.193 1.00 136.60 ? 713 ALA A CB  1 
ATOM   5339 N N   . ARG A 1 713 ? 149.085 166.866 114.820 1.00 141.13 ? 714 ARG A N   1 
ATOM   5340 C CA  . ARG A 1 713 ? 147.890 166.871 115.651 1.00 134.61 ? 714 ARG A CA  1 
ATOM   5341 C C   . ARG A 1 713 ? 147.416 165.464 115.988 1.00 135.17 ? 714 ARG A C   1 
ATOM   5342 O O   . ARG A 1 713 ? 146.532 165.322 116.841 1.00 129.59 ? 714 ARG A O   1 
ATOM   5343 C CB  . ARG A 1 713 ? 146.748 167.630 114.958 1.00 135.10 ? 714 ARG A CB  1 
ATOM   5344 C CG  . ARG A 1 713 ? 146.794 169.165 115.026 1.00 134.56 ? 714 ARG A CG  1 
ATOM   5345 C CD  . ARG A 1 713 ? 147.811 169.782 114.066 1.00 136.67 ? 714 ARG A CD  1 
ATOM   5346 N NE  . ARG A 1 713 ? 147.814 171.239 114.110 1.00 147.77 ? 714 ARG A NE  1 
ATOM   5347 C CZ  . ARG A 1 713 ? 147.028 172.011 113.374 1.00 147.41 ? 714 ARG A CZ  1 
ATOM   5348 N NH1 . ARG A 1 713 ? 146.157 171.498 112.522 1.00 148.03 ? 714 ARG A NH1 1 
ATOM   5349 N NH2 . ARG A 1 713 ? 147.120 173.332 113.494 1.00 145.16 ? 714 ARG A NH2 1 
ATOM   5350 N N   . ASN A 1 714 ? 147.991 164.447 115.332 1.00 134.56 ? 715 ASN A N   1 
ATOM   5351 C CA  . ASN A 1 714 ? 147.632 163.030 115.462 1.00 130.37 ? 715 ASN A CA  1 
ATOM   5352 C C   . ASN A 1 714 ? 146.151 162.793 115.157 1.00 128.13 ? 715 ASN A C   1 
ATOM   5353 O O   . ASN A 1 714 ? 145.426 162.149 115.917 1.00 128.44 ? 715 ASN A O   1 
ATOM   5354 C CB  . ASN A 1 714 ? 148.007 162.478 116.845 1.00 127.82 ? 715 ASN A CB  1 
ATOM   5355 C CG  . ASN A 1 714 ? 149.356 161.789 116.853 1.00 125.58 ? 715 ASN A CG  1 
ATOM   5356 O OD1 . ASN A 1 714 ? 150.230 162.102 116.047 1.00 127.68 ? 715 ASN A OD1 1 
ATOM   5357 N ND2 . ASN A 1 714 ? 149.529 160.840 117.766 1.00 119.05 ? 715 ASN A ND2 1 
ATOM   5358 N N   . THR A 1 715 ? 145.706 163.328 114.019 1.00 125.09 ? 716 THR A N   1 
ATOM   5359 C CA  . THR A 1 715 ? 144.308 163.197 113.628 1.00 124.97 ? 716 THR A CA  1 
ATOM   5360 C C   . THR A 1 715 ? 144.210 162.839 112.153 1.00 127.32 ? 716 THR A C   1 
ATOM   5361 O O   . THR A 1 715 ? 145.075 163.206 111.355 1.00 130.00 ? 716 THR A O   1 
ATOM   5362 C CB  . THR A 1 715 ? 143.520 164.488 113.885 1.00 134.41 ? 716 THR A CB  1 
ATOM   5363 O OG1 . THR A 1 715 ? 144.302 165.617 113.475 1.00 132.56 ? 716 THR A OG1 1 
ATOM   5364 C CG2 . THR A 1 715 ? 143.145 164.624 115.358 1.00 139.38 ? 716 THR A CG2 1 
ATOM   5365 N N   . VAL A 1 716 ? 143.140 162.131 111.789 1.00 126.03 ? 717 VAL A N   1 
ATOM   5366 C CA  . VAL A 1 716 ? 142.828 161.866 110.389 1.00 121.77 ? 717 VAL A CA  1 
ATOM   5367 C C   . VAL A 1 716 ? 141.379 162.266 110.139 1.00 125.49 ? 717 VAL A C   1 
ATOM   5368 O O   . VAL A 1 716 ? 140.522 162.114 111.015 1.00 127.51 ? 717 VAL A O   1 
ATOM   5369 C CB  . VAL A 1 716 ? 143.084 160.391 110.004 1.00 117.70 ? 717 VAL A CB  1 
ATOM   5370 C CG1 . VAL A 1 716 ? 144.563 160.116 109.884 1.00 120.56 ? 717 VAL A CG1 1 
ATOM   5371 C CG2 . VAL A 1 716 ? 142.546 159.483 111.048 1.00 119.28 ? 717 VAL A CG2 1 
ATOM   5372 N N   . TYR A 1 717 ? 141.117 162.836 108.964 1.00 121.90 ? 718 TYR A N   1 
ATOM   5373 C CA  . TYR A 1 717 ? 139.799 163.339 108.607 1.00 122.59 ? 718 TYR A CA  1 
ATOM   5374 C C   . TYR A 1 717 ? 139.351 162.747 107.279 1.00 127.65 ? 718 TYR A C   1 
ATOM   5375 O O   . TYR A 1 717 ? 140.160 162.503 106.376 1.00 127.29 ? 718 TYR A O   1 
ATOM   5376 C CB  . TYR A 1 717 ? 139.771 164.875 108.486 1.00 123.30 ? 718 TYR A CB  1 
ATOM   5377 C CG  . TYR A 1 717 ? 140.483 165.643 109.577 1.00 122.35 ? 718 TYR A CG  1 
ATOM   5378 C CD1 . TYR A 1 717 ? 140.260 165.359 110.918 1.00 124.47 ? 718 TYR A CD1 1 
ATOM   5379 C CD2 . TYR A 1 717 ? 141.375 166.660 109.260 1.00 125.01 ? 718 TYR A CD2 1 
ATOM   5380 C CE1 . TYR A 1 717 ? 140.907 166.065 111.912 1.00 135.02 ? 718 TYR A CE1 1 
ATOM   5381 C CE2 . TYR A 1 717 ? 142.027 167.370 110.246 1.00 132.62 ? 718 TYR A CE2 1 
ATOM   5382 C CZ  . TYR A 1 717 ? 141.791 167.068 111.571 1.00 141.61 ? 718 TYR A CZ  1 
ATOM   5383 O OH  . TYR A 1 717 ? 142.440 167.773 112.558 1.00 144.83 ? 718 TYR A OH  1 
ATOM   5384 N N   . LEU A 1 718 ? 138.043 162.534 107.166 1.00 125.81 ? 719 LEU A N   1 
ATOM   5385 C CA  . LEU A 1 718 ? 137.411 162.135 105.918 1.00 122.40 ? 719 LEU A CA  1 
ATOM   5386 C C   . LEU A 1 718 ? 136.309 163.133 105.597 1.00 124.45 ? 719 LEU A C   1 
ATOM   5387 O O   . LEU A 1 718 ? 135.437 163.392 106.434 1.00 126.02 ? 719 LEU A O   1 
ATOM   5388 C CB  . LEU A 1 718 ? 136.848 160.716 106.011 1.00 120.16 ? 719 LEU A CB  1 
ATOM   5389 C CG  . LEU A 1 718 ? 136.213 160.149 104.742 1.00 124.49 ? 719 LEU A CG  1 
ATOM   5390 C CD1 . LEU A 1 718 ? 137.241 160.045 103.632 1.00 127.98 ? 719 LEU A CD1 1 
ATOM   5391 C CD2 . LEU A 1 718 ? 135.582 158.795 105.019 1.00 124.69 ? 719 LEU A CD2 1 
ATOM   5392 N N   . GLN A 1 719 ? 136.348 163.693 104.392 1.00 123.60 ? 720 GLN A N   1 
ATOM   5393 C CA  . GLN A 1 719 ? 135.424 164.738 103.980 1.00 124.39 ? 720 GLN A CA  1 
ATOM   5394 C C   . GLN A 1 719 ? 134.546 164.198 102.861 1.00 128.99 ? 720 GLN A C   1 
ATOM   5395 O O   . GLN A 1 719 ? 135.047 163.586 101.911 1.00 129.02 ? 720 GLN A O   1 
ATOM   5396 C CB  . GLN A 1 719 ? 136.192 165.990 103.541 1.00 125.88 ? 720 GLN A CB  1 
ATOM   5397 C CG  . GLN A 1 719 ? 135.347 167.238 103.302 1.00 127.22 ? 720 GLN A CG  1 
ATOM   5398 C CD  . GLN A 1 719 ? 134.794 167.329 101.899 1.00 129.24 ? 720 GLN A CD  1 
ATOM   5399 O OE1 . GLN A 1 719 ? 135.398 166.828 100.951 1.00 135.16 ? 720 GLN A OE1 1 
ATOM   5400 N NE2 . GLN A 1 719 ? 133.641 167.969 101.757 1.00 129.45 ? 720 GLN A NE2 1 
ATOM   5401 N N   . MET A 1 720 ? 133.242 164.429 102.979 1.00 135.11 ? 721 MET A N   1 
ATOM   5402 C CA  . MET A 1 720 ? 132.228 163.826 102.121 1.00 133.93 ? 721 MET A CA  1 
ATOM   5403 C C   . MET A 1 720 ? 131.559 164.924 101.304 1.00 137.58 ? 721 MET A C   1 
ATOM   5404 O O   . MET A 1 720 ? 131.000 165.871 101.870 1.00 140.47 ? 721 MET A O   1 
ATOM   5405 C CB  . MET A 1 720 ? 131.202 163.064 102.961 1.00 131.85 ? 721 MET A CB  1 
ATOM   5406 C CG  . MET A 1 720 ? 131.684 161.716 103.479 1.00 133.25 ? 721 MET A CG  1 
ATOM   5407 S SD  . MET A 1 720 ? 132.886 161.800 104.821 1.00 146.66 ? 721 MET A SD  1 
ATOM   5408 C CE  . MET A 1 720 ? 131.848 162.255 106.203 1.00 130.29 ? 721 MET A CE  1 
ATOM   5409 N N   . ASN A 1 721 ? 131.611 164.789 99.981  1.00 141.53 ? 722 ASN A N   1 
ATOM   5410 C CA  . ASN A 1 721 ? 130.957 165.703 99.053  1.00 143.91 ? 722 ASN A CA  1 
ATOM   5411 C C   . ASN A 1 721 ? 129.872 164.961 98.288  1.00 142.19 ? 722 ASN A C   1 
ATOM   5412 O O   . ASN A 1 721 ? 130.083 163.816 97.871  1.00 139.98 ? 722 ASN A O   1 
ATOM   5413 C CB  . ASN A 1 721 ? 131.958 166.309 98.065  1.00 148.97 ? 722 ASN A CB  1 
ATOM   5414 C CG  . ASN A 1 721 ? 133.180 166.879 98.745  1.00 147.78 ? 722 ASN A CG  1 
ATOM   5415 O OD1 . ASN A 1 721 ? 133.125 167.956 99.338  1.00 146.15 ? 722 ASN A OD1 1 
ATOM   5416 N ND2 . ASN A 1 721 ? 134.294 166.162 98.664  1.00 141.44 ? 722 ASN A ND2 1 
ATOM   5417 N N   . SER A 1 722 ? 128.724 165.627 98.111  1.00 146.09 ? 723 SER A N   1 
ATOM   5418 C CA  . SER A 1 722 ? 127.565 165.141 97.353  1.00 154.13 ? 723 SER A CA  1 
ATOM   5419 C C   . SER A 1 722 ? 127.050 163.813 97.919  1.00 152.61 ? 723 SER A C   1 
ATOM   5420 O O   . SER A 1 722 ? 127.110 162.758 97.285  1.00 151.82 ? 723 SER A O   1 
ATOM   5421 C CB  . SER A 1 722 ? 127.889 165.029 95.856  1.00 157.11 ? 723 SER A CB  1 
ATOM   5422 O OG  . SER A 1 722 ? 128.439 166.238 95.363  1.00 161.19 ? 723 SER A OG  1 
ATOM   5423 N N   . LEU A 1 723 ? 126.559 163.903 99.152  1.00 148.88 ? 724 LEU A N   1 
ATOM   5424 C CA  . LEU A 1 723 ? 126.051 162.734 99.855  1.00 148.10 ? 724 LEU A CA  1 
ATOM   5425 C C   . LEU A 1 723 ? 124.765 162.218 99.217  1.00 155.01 ? 724 LEU A C   1 
ATOM   5426 O O   . LEU A 1 723 ? 123.967 162.975 98.659  1.00 158.04 ? 724 LEU A O   1 
ATOM   5427 C CB  . LEU A 1 723 ? 125.804 163.050 101.332 1.00 152.42 ? 724 LEU A CB  1 
ATOM   5428 C CG  . LEU A 1 723 ? 126.996 163.085 102.295 1.00 153.58 ? 724 LEU A CG  1 
ATOM   5429 C CD1 . LEU A 1 723 ? 127.734 164.413 102.261 1.00 146.75 ? 724 LEU A CD1 1 
ATOM   5430 C CD2 . LEU A 1 723 ? 126.539 162.767 103.711 1.00 155.31 ? 724 LEU A CD2 1 
ATOM   5431 N N   . LYS A 1 724 ? 124.579 160.910 99.312  1.00 155.12 ? 725 LYS A N   1 
ATOM   5432 C CA  . LYS A 1 724 ? 123.455 160.184 98.746  1.00 155.77 ? 725 LYS A CA  1 
ATOM   5433 C C   . LYS A 1 724 ? 122.879 159.304 99.845  1.00 153.55 ? 725 LYS A C   1 
ATOM   5434 O O   . LYS A 1 724 ? 123.552 159.050 100.850 1.00 156.35 ? 725 LYS A O   1 
ATOM   5435 C CB  . LYS A 1 724 ? 123.904 159.345 97.538  1.00 152.51 ? 725 LYS A CB  1 
ATOM   5436 C CG  . LYS A 1 724 ? 124.098 160.155 96.266  1.00 151.75 ? 725 LYS A CG  1 
ATOM   5437 C CD  . LYS A 1 724 ? 124.344 159.256 95.065  1.00 154.91 ? 725 LYS A CD  1 
ATOM   5438 C CE  . LYS A 1 724 ? 124.673 160.071 93.825  1.00 159.80 ? 725 LYS A CE  1 
ATOM   5439 N NZ  . LYS A 1 724 ? 124.867 159.209 92.626  1.00 159.96 ? 725 LYS A NZ  1 
ATOM   5440 N N   . PRO A 1 725 ? 121.621 158.854 99.707  1.00 149.32 ? 726 PRO A N   1 
ATOM   5441 C CA  . PRO A 1 725 ? 121.073 157.925 100.714 1.00 150.36 ? 726 PRO A CA  1 
ATOM   5442 C C   . PRO A 1 725 ? 121.761 156.567 100.762 1.00 151.42 ? 726 PRO A C   1 
ATOM   5443 O O   . PRO A 1 725 ? 121.602 155.845 101.755 1.00 147.71 ? 726 PRO A O   1 
ATOM   5444 C CB  . PRO A 1 725 ? 119.600 157.795 100.302 1.00 153.90 ? 726 PRO A CB  1 
ATOM   5445 C CG  . PRO A 1 725 ? 119.566 158.196 98.871  1.00 153.37 ? 726 PRO A CG  1 
ATOM   5446 C CD  . PRO A 1 725 ? 120.566 159.300 98.779  1.00 153.45 ? 726 PRO A CD  1 
ATOM   5447 N N   . GLU A 1 726 ? 122.514 156.196 99.722  1.00 153.89 ? 727 GLU A N   1 
ATOM   5448 C CA  . GLU A 1 726 ? 123.274 154.950 99.734  1.00 154.46 ? 727 GLU A CA  1 
ATOM   5449 C C   . GLU A 1 726 ? 124.400 154.974 100.766 1.00 151.18 ? 727 GLU A C   1 
ATOM   5450 O O   . GLU A 1 726 ? 124.797 153.912 101.259 1.00 150.93 ? 727 GLU A O   1 
ATOM   5451 C CB  . GLU A 1 726 ? 123.812 154.681 98.318  1.00 151.01 ? 727 GLU A CB  1 
ATOM   5452 C CG  . GLU A 1 726 ? 124.420 153.297 98.048  1.00 150.38 ? 727 GLU A CG  1 
ATOM   5453 C CD  . GLU A 1 726 ? 125.886 153.188 98.428  1.00 152.90 ? 727 GLU A CD  1 
ATOM   5454 O OE1 . GLU A 1 726 ? 126.592 154.217 98.381  1.00 155.30 ? 727 GLU A OE1 1 
ATOM   5455 O OE2 . GLU A 1 726 ? 126.332 152.073 98.772  1.00 151.41 ? 727 GLU A OE2 1 
ATOM   5456 N N   . ASP A 1 727 ? 124.895 156.155 101.132 1.00 146.78 ? 728 ASP A N   1 
ATOM   5457 C CA  . ASP A 1 727 ? 126.020 156.283 102.049 1.00 145.39 ? 728 ASP A CA  1 
ATOM   5458 C C   . ASP A 1 727 ? 125.612 156.296 103.519 1.00 141.68 ? 728 ASP A C   1 
ATOM   5459 O O   . ASP A 1 727 ? 126.466 156.546 104.377 1.00 137.16 ? 728 ASP A O   1 
ATOM   5460 C CB  . ASP A 1 727 ? 126.813 157.552 101.728 1.00 142.81 ? 728 ASP A CB  1 
ATOM   5461 C CG  . ASP A 1 727 ? 127.544 157.458 100.409 1.00 139.27 ? 728 ASP A CG  1 
ATOM   5462 O OD1 . ASP A 1 727 ? 127.908 156.332 100.012 1.00 136.95 ? 728 ASP A OD1 1 
ATOM   5463 O OD2 . ASP A 1 727 ? 127.758 158.508 99.771  1.00 144.92 ? 728 ASP A OD2 1 
ATOM   5464 N N   . THR A 1 728 ? 124.340 156.052 103.831 1.00 134.95 ? 729 THR A N   1 
ATOM   5465 C CA  . THR A 1 728 ? 123.902 155.951 105.219 1.00 130.99 ? 729 THR A CA  1 
ATOM   5466 C C   . THR A 1 728 ? 124.477 154.681 105.840 1.00 130.49 ? 729 THR A C   1 
ATOM   5467 O O   . THR A 1 728 ? 124.099 153.570 105.449 1.00 138.71 ? 729 THR A O   1 
ATOM   5468 C CB  . THR A 1 728 ? 122.374 155.946 105.280 1.00 137.65 ? 729 THR A CB  1 
ATOM   5469 O OG1 . THR A 1 728 ? 121.879 157.244 104.928 1.00 138.80 ? 729 THR A OG1 1 
ATOM   5470 C CG2 . THR A 1 728 ? 121.868 155.582 106.678 1.00 136.62 ? 729 THR A CG2 1 
ATOM   5471 N N   . ALA A 1 729 ? 125.396 154.841 106.793 1.00 121.32 ? 730 ALA A N   1 
ATOM   5472 C CA  . ALA A 1 729 ? 126.143 153.704 107.333 1.00 119.33 ? 730 ALA A CA  1 
ATOM   5473 C C   . ALA A 1 729 ? 126.823 154.119 108.632 1.00 114.68 ? 730 ALA A C   1 
ATOM   5474 O O   . ALA A 1 729 ? 126.867 155.300 108.988 1.00 119.35 ? 730 ALA A O   1 
ATOM   5475 C CB  . ALA A 1 729 ? 127.183 153.182 106.336 1.00 123.09 ? 730 ALA A CB  1 
ATOM   5476 N N   . VAL A 1 730 ? 127.375 153.130 109.330 1.00 112.44 ? 731 VAL A N   1 
ATOM   5477 C CA  . VAL A 1 730 ? 128.228 153.348 110.492 1.00 107.65 ? 731 VAL A CA  1 
ATOM   5478 C C   . VAL A 1 730 ? 129.676 153.240 110.033 1.00 105.81 ? 731 VAL A C   1 
ATOM   5479 O O   . VAL A 1 730 ? 130.063 152.245 109.413 1.00 109.98 ? 731 VAL A O   1 
ATOM   5480 C CB  . VAL A 1 730 ? 127.926 152.329 111.604 1.00 107.64 ? 731 VAL A CB  1 
ATOM   5481 C CG1 . VAL A 1 730 ? 128.877 152.512 112.775 1.00 108.64 ? 731 VAL A CG1 1 
ATOM   5482 C CG2 . VAL A 1 730 ? 126.482 152.441 112.052 1.00 114.67 ? 731 VAL A CG2 1 
ATOM   5483 N N   . TYR A 1 731 ? 130.474 154.257 110.330 1.00 104.05 ? 732 TYR A N   1 
ATOM   5484 C CA  . TYR A 1 731 ? 131.840 154.360 109.839 1.00 102.41 ? 732 TYR A CA  1 
ATOM   5485 C C   . TYR A 1 731 ? 132.827 154.061 110.959 1.00 105.38 ? 732 TYR A C   1 
ATOM   5486 O O   . TYR A 1 731 ? 132.654 154.520 112.094 1.00 111.44 ? 732 TYR A O   1 
ATOM   5487 C CB  . TYR A 1 731 ? 132.113 155.750 109.252 1.00 109.03 ? 732 TYR A CB  1 
ATOM   5488 C CG  . TYR A 1 731 ? 131.462 156.027 107.906 1.00 112.90 ? 732 TYR A CG  1 
ATOM   5489 C CD1 . TYR A 1 731 ? 130.737 155.047 107.234 1.00 111.01 ? 732 TYR A CD1 1 
ATOM   5490 C CD2 . TYR A 1 731 ? 131.573 157.277 107.310 1.00 116.44 ? 732 TYR A CD2 1 
ATOM   5491 C CE1 . TYR A 1 731 ? 130.144 155.304 106.013 1.00 111.95 ? 732 TYR A CE1 1 
ATOM   5492 C CE2 . TYR A 1 731 ? 130.983 157.542 106.086 1.00 118.24 ? 732 TYR A CE2 1 
ATOM   5493 C CZ  . TYR A 1 731 ? 130.271 156.550 105.445 1.00 116.53 ? 732 TYR A CZ  1 
ATOM   5494 O OH  . TYR A 1 731 ? 129.682 156.803 104.229 1.00 131.37 ? 732 TYR A OH  1 
ATOM   5495 N N   . TYR A 1 732 ? 133.858 153.285 110.624 1.00 105.05 ? 733 TYR A N   1 
ATOM   5496 C CA  . TYR A 1 732 ? 134.901 152.883 111.558 1.00 102.32 ? 733 TYR A CA  1 
ATOM   5497 C C   . TYR A 1 732 ? 136.267 153.205 110.967 1.00 105.16 ? 733 TYR A C   1 
ATOM   5498 O O   . TYR A 1 732 ? 136.422 153.381 109.758 1.00 106.03 ? 733 TYR A O   1 
ATOM   5499 C CB  . TYR A 1 732 ? 134.861 151.380 111.915 1.00 103.46 ? 733 TYR A CB  1 
ATOM   5500 C CG  . TYR A 1 732 ? 133.522 150.792 112.325 1.00 101.24 ? 733 TYR A CG  1 
ATOM   5501 C CD1 . TYR A 1 732 ? 132.536 150.498 111.386 1.00 106.45 ? 733 TYR A CD1 1 
ATOM   5502 C CD2 . TYR A 1 732 ? 133.253 150.519 113.660 1.00 98.07  ? 733 TYR A CD2 1 
ATOM   5503 C CE1 . TYR A 1 732 ? 131.324 149.957 111.768 1.00 105.40 ? 733 TYR A CE1 1 
ATOM   5504 C CE2 . TYR A 1 732 ? 132.042 149.979 114.050 1.00 99.30  ? 733 TYR A CE2 1 
ATOM   5505 C CZ  . TYR A 1 732 ? 131.083 149.700 113.100 1.00 97.83  ? 733 TYR A CZ  1 
ATOM   5506 O OH  . TYR A 1 732 ? 129.878 149.162 113.484 1.00 99.29  ? 733 TYR A OH  1 
ATOM   5507 N N   . CYS A 1 733 ? 137.267 153.237 111.845 1.00 113.44 ? 734 CYS A N   1 
ATOM   5508 C CA  . CYS A 1 733 ? 138.611 153.711 111.535 1.00 113.10 ? 734 CYS A CA  1 
ATOM   5509 C C   . CYS A 1 733 ? 139.603 152.630 111.949 1.00 110.04 ? 734 CYS A C   1 
ATOM   5510 O O   . CYS A 1 733 ? 139.627 152.224 113.115 1.00 111.53 ? 734 CYS A O   1 
ATOM   5511 C CB  . CYS A 1 733 ? 138.854 155.030 112.271 1.00 113.90 ? 734 CYS A CB  1 
ATOM   5512 S SG  . CYS A 1 733 ? 140.375 155.948 112.079 1.00 132.98 ? 734 CYS A SG  1 
ATOM   5513 N N   . ASN A 1 734 ? 140.414 152.165 111.000 1.00 105.05 ? 735 ASN A N   1 
ATOM   5514 C CA  . ASN A 1 734 ? 141.211 150.955 111.157 1.00 107.54 ? 735 ASN A CA  1 
ATOM   5515 C C   . ASN A 1 734 ? 142.697 151.281 111.094 1.00 111.49 ? 735 ASN A C   1 
ATOM   5516 O O   . ASN A 1 734 ? 143.139 152.057 110.237 1.00 113.90 ? 735 ASN A O   1 
ATOM   5517 C CB  . ASN A 1 734 ? 140.855 149.929 110.067 1.00 114.50 ? 735 ASN A CB  1 
ATOM   5518 C CG  . ASN A 1 734 ? 141.801 148.732 110.037 1.00 113.14 ? 735 ASN A CG  1 
ATOM   5519 O OD1 . ASN A 1 734 ? 142.259 148.250 111.074 1.00 110.10 ? 735 ASN A OD1 1 
ATOM   5520 N ND2 . ASN A 1 734 ? 142.097 148.250 108.836 1.00 109.73 ? 735 ASN A ND2 1 
ATOM   5521 N N   . VAL A 1 735 ? 143.461 150.659 111.994 1.00 110.54 ? 736 VAL A N   1 
ATOM   5522 C CA  . VAL A 1 735 ? 144.911 150.818 112.045 1.00 103.40 ? 736 VAL A CA  1 
ATOM   5523 C C   . VAL A 1 735 ? 145.536 149.453 112.331 1.00 110.31 ? 736 VAL A C   1 
ATOM   5524 O O   . VAL A 1 735 ? 144.938 148.606 113.005 1.00 117.19 ? 736 VAL A O   1 
ATOM   5525 C CB  . VAL A 1 735 ? 145.310 151.891 113.089 1.00 109.53 ? 736 VAL A CB  1 
ATOM   5526 C CG1 . VAL A 1 735 ? 144.949 151.468 114.512 1.00 113.28 ? 736 VAL A CG1 1 
ATOM   5527 C CG2 . VAL A 1 735 ? 146.782 152.282 112.969 1.00 115.46 ? 736 VAL A CG2 1 
ATOM   5528 N N   . ASN A 1 736 ? 146.718 149.219 111.763 1.00 111.50 ? 737 ASN A N   1 
ATOM   5529 C CA  . ASN A 1 736 ? 147.503 148.021 112.030 1.00 114.95 ? 737 ASN A CA  1 
ATOM   5530 C C   . ASN A 1 736 ? 148.818 148.456 112.665 1.00 118.72 ? 737 ASN A C   1 
ATOM   5531 O O   . ASN A 1 736 ? 149.677 149.035 111.991 1.00 120.27 ? 737 ASN A O   1 
ATOM   5532 C CB  . ASN A 1 736 ? 147.718 147.214 110.743 1.00 113.39 ? 737 ASN A CB  1 
ATOM   5533 C CG  . ASN A 1 736 ? 148.785 146.115 110.871 1.00 120.54 ? 737 ASN A CG  1 
ATOM   5534 O OD1 . ASN A 1 736 ? 149.992 146.370 110.894 1.00 120.45 ? 737 ASN A OD1 1 
ATOM   5535 N ND2 . ASN A 1 736 ? 148.321 144.873 110.953 1.00 114.63 ? 737 ASN A ND2 1 
ATOM   5536 N N   . VAL A 1 737 ? 148.968 148.175 113.957 1.00 118.12 ? 738 VAL A N   1 
ATOM   5537 C CA  . VAL A 1 737 ? 150.209 148.387 114.692 1.00 121.26 ? 738 VAL A CA  1 
ATOM   5538 C C   . VAL A 1 737 ? 151.091 147.145 114.656 1.00 131.10 ? 738 VAL A C   1 
ATOM   5539 O O   . VAL A 1 737 ? 152.329 147.258 114.686 1.00 143.00 ? 738 VAL A O   1 
ATOM   5540 C CB  . VAL A 1 737 ? 149.896 148.823 116.143 1.00 119.31 ? 738 VAL A CB  1 
ATOM   5541 C CG1 . VAL A 1 737 ? 151.142 149.027 117.017 1.00 125.72 ? 738 VAL A CG1 1 
ATOM   5542 C CG2 . VAL A 1 737 ? 149.042 150.083 116.137 1.00 117.78 ? 738 VAL A CG2 1 
ATOM   5543 N N   . GLY A 1 738 ? 150.493 145.981 114.430 1.00 126.14 ? 739 GLY A N   1 
ATOM   5544 C CA  . GLY A 1 738 ? 151.108 144.684 114.622 1.00 123.99 ? 739 GLY A CA  1 
ATOM   5545 C C   . GLY A 1 738 ? 150.018 143.788 115.164 1.00 122.17 ? 739 GLY A C   1 
ATOM   5546 O O   . GLY A 1 738 ? 150.044 142.564 115.014 1.00 120.40 ? 739 GLY A O   1 
ATOM   5547 N N   . PHE A 1 739 ? 149.042 144.426 115.798 1.00 119.39 ? 740 PHE A N   1 
ATOM   5548 C CA  . PHE A 1 739 ? 147.744 143.840 116.087 1.00 118.38 ? 740 PHE A CA  1 
ATOM   5549 C C   . PHE A 1 739 ? 146.707 144.825 115.568 1.00 120.63 ? 740 PHE A C   1 
ATOM   5550 O O   . PHE A 1 739 ? 146.936 146.037 115.590 1.00 127.22 ? 740 PHE A O   1 
ATOM   5551 C CB  . PHE A 1 739 ? 147.550 143.567 117.593 1.00 115.78 ? 740 PHE A CB  1 
ATOM   5552 C CG  . PHE A 1 739 ? 148.474 142.505 118.156 1.00 118.70 ? 740 PHE A CG  1 
ATOM   5553 C CD1 . PHE A 1 739 ? 149.791 142.803 118.478 1.00 116.16 ? 740 PHE A CD1 1 
ATOM   5554 C CD2 . PHE A 1 739 ? 148.021 141.210 118.364 1.00 111.92 ? 740 PHE A CD2 1 
ATOM   5555 C CE1 . PHE A 1 739 ? 150.633 141.833 118.990 1.00 111.55 ? 740 PHE A CE1 1 
ATOM   5556 C CE2 . PHE A 1 739 ? 148.858 140.236 118.873 1.00 101.80 ? 740 PHE A CE2 1 
ATOM   5557 C CZ  . PHE A 1 739 ? 150.164 140.549 119.187 1.00 107.49 ? 740 PHE A CZ  1 
ATOM   5558 N N   . GLU A 1 740 ? 145.586 144.313 115.071 1.00 112.88 ? 741 GLU A N   1 
ATOM   5559 C CA  . GLU A 1 740 ? 144.599 145.158 114.411 1.00 111.46 ? 741 GLU A CA  1 
ATOM   5560 C C   . GLU A 1 740 ? 143.789 145.927 115.449 1.00 116.01 ? 741 GLU A C   1 
ATOM   5561 O O   . GLU A 1 740 ? 143.384 145.361 116.468 1.00 122.38 ? 741 GLU A O   1 
ATOM   5562 C CB  . GLU A 1 740 ? 143.667 144.305 113.552 1.00 119.32 ? 741 GLU A CB  1 
ATOM   5563 C CG  . GLU A 1 740 ? 142.668 145.096 112.728 1.00 121.06 ? 741 GLU A CG  1 
ATOM   5564 C CD  . GLU A 1 740 ? 141.777 144.207 111.891 1.00 122.34 ? 741 GLU A CD  1 
ATOM   5565 O OE1 . GLU A 1 740 ? 141.898 142.971 111.996 1.00 122.26 ? 741 GLU A OE1 1 
ATOM   5566 O OE2 . GLU A 1 740 ? 140.976 144.745 111.104 1.00 124.41 ? 741 GLU A OE2 1 
ATOM   5567 N N   . TYR A 1 741 ? 143.545 147.214 115.196 1.00 111.60 ? 742 TYR A N   1 
ATOM   5568 C CA  . TYR A 1 741 ? 142.672 147.999 116.053 1.00 110.79 ? 742 TYR A CA  1 
ATOM   5569 C C   . TYR A 1 741 ? 141.665 148.791 115.230 1.00 114.07 ? 742 TYR A C   1 
ATOM   5570 O O   . TYR A 1 741 ? 141.992 149.359 114.181 1.00 116.03 ? 742 TYR A O   1 
ATOM   5571 C CB  . TYR A 1 741 ? 143.466 148.949 116.956 1.00 111.38 ? 742 TYR A CB  1 
ATOM   5572 C CG  . TYR A 1 741 ? 144.489 148.254 117.822 1.00 111.18 ? 742 TYR A CG  1 
ATOM   5573 C CD1 . TYR A 1 741 ? 144.095 147.521 118.935 1.00 116.41 ? 742 TYR A CD1 1 
ATOM   5574 C CD2 . TYR A 1 741 ? 145.845 148.347 117.545 1.00 110.52 ? 742 TYR A CD2 1 
ATOM   5575 C CE1 . TYR A 1 741 ? 145.021 146.884 119.736 1.00 104.70 ? 742 TYR A CE1 1 
ATOM   5576 C CE2 . TYR A 1 741 ? 146.781 147.715 118.345 1.00 113.04 ? 742 TYR A CE2 1 
ATOM   5577 C CZ  . TYR A 1 741 ? 146.360 146.985 119.437 1.00 101.60 ? 742 TYR A CZ  1 
ATOM   5578 O OH  . TYR A 1 741 ? 147.283 146.353 120.236 1.00 105.55 ? 742 TYR A OH  1 
ATOM   5579 N N   . TRP A 1 742 ? 140.430 148.814 115.724 1.00 115.86 ? 743 TRP A N   1 
ATOM   5580 C CA  . TRP A 1 742 ? 139.328 149.575 115.156 1.00 114.48 ? 743 TRP A CA  1 
ATOM   5581 C C   . TRP A 1 742 ? 138.803 150.576 116.176 1.00 114.57 ? 743 TRP A C   1 
ATOM   5582 O O   . TRP A 1 742 ? 138.939 150.399 117.389 1.00 117.78 ? 743 TRP A O   1 
ATOM   5583 C CB  . TRP A 1 742 ? 138.188 148.658 114.696 1.00 111.97 ? 743 TRP A CB  1 
ATOM   5584 C CG  . TRP A 1 742 ? 138.504 147.838 113.492 1.00 120.70 ? 743 TRP A CG  1 
ATOM   5585 C CD1 . TRP A 1 742 ? 139.611 147.927 112.710 1.00 123.14 ? 743 TRP A CD1 1 
ATOM   5586 C CD2 . TRP A 1 742 ? 137.687 146.814 112.916 1.00 123.73 ? 743 TRP A CD2 1 
ATOM   5587 N NE1 . TRP A 1 742 ? 139.544 147.016 111.685 1.00 122.13 ? 743 TRP A NE1 1 
ATOM   5588 C CE2 . TRP A 1 742 ? 138.370 146.321 111.789 1.00 121.63 ? 743 TRP A CE2 1 
ATOM   5589 C CE3 . TRP A 1 742 ? 136.448 146.264 113.246 1.00 122.75 ? 743 TRP A CE3 1 
ATOM   5590 C CZ2 . TRP A 1 742 ? 137.855 145.304 110.992 1.00 120.42 ? 743 TRP A CZ2 1 
ATOM   5591 C CZ3 . TRP A 1 742 ? 135.943 145.254 112.455 1.00 120.53 ? 743 TRP A CZ3 1 
ATOM   5592 C CH2 . TRP A 1 742 ? 136.643 144.785 111.341 1.00 124.13 ? 743 TRP A CH2 1 
ATOM   5593 N N   . GLY A 1 743 ? 138.191 151.641 115.665 1.00 107.66 ? 744 GLY A N   1 
ATOM   5594 C CA  . GLY A 1 743 ? 137.567 152.645 116.497 1.00 104.89 ? 744 GLY A CA  1 
ATOM   5595 C C   . GLY A 1 743 ? 136.155 152.258 116.891 1.00 111.15 ? 744 GLY A C   1 
ATOM   5596 O O   . GLY A 1 743 ? 135.685 151.147 116.642 1.00 116.43 ? 744 GLY A O   1 
ATOM   5597 N N   . GLN A 1 744 ? 135.469 153.209 117.527 1.00 111.07 ? 745 GLN A N   1 
ATOM   5598 C CA  . GLN A 1 744 ? 134.116 152.955 118.007 1.00 114.86 ? 745 GLN A CA  1 
ATOM   5599 C C   . GLN A 1 744 ? 133.097 152.983 116.874 1.00 112.69 ? 745 GLN A C   1 
ATOM   5600 O O   . GLN A 1 744 ? 132.144 152.196 116.873 1.00 106.59 ? 745 GLN A O   1 
ATOM   5601 C CB  . GLN A 1 744 ? 133.748 153.979 119.086 1.00 120.74 ? 745 GLN A CB  1 
ATOM   5602 C CG  . GLN A 1 744 ? 134.728 154.128 120.275 1.00 117.48 ? 745 GLN A CG  1 
ATOM   5603 C CD  . GLN A 1 744 ? 135.382 152.838 120.782 1.00 118.14 ? 745 GLN A CD  1 
ATOM   5604 O OE1 . GLN A 1 744 ? 134.743 151.789 120.911 1.00 116.46 ? 745 GLN A OE1 1 
ATOM   5605 N NE2 . GLN A 1 744 ? 136.676 152.920 121.067 1.00 113.55 ? 745 GLN A NE2 1 
ATOM   5606 N N   . GLY A 1 745 ? 133.278 153.870 115.911 1.00 111.22 ? 746 GLY A N   1 
ATOM   5607 C CA  . GLY A 1 745 ? 132.351 153.998 114.798 1.00 110.86 ? 746 GLY A CA  1 
ATOM   5608 C C   . GLY A 1 745 ? 131.222 154.961 115.100 1.00 111.91 ? 746 GLY A C   1 
ATOM   5609 O O   . GLY A 1 745 ? 130.722 155.054 116.219 1.00 116.67 ? 746 GLY A O   1 
ATOM   5610 N N   . THR A 1 746 ? 130.812 155.700 114.071 1.00 109.83 ? 747 THR A N   1 
ATOM   5611 C CA  . THR A 1 746 ? 129.738 156.672 114.225 1.00 114.75 ? 747 THR A CA  1 
ATOM   5612 C C   . THR A 1 746 ? 128.749 156.532 113.079 1.00 115.95 ? 747 THR A C   1 
ATOM   5613 O O   . THR A 1 746 ? 129.103 156.109 111.979 1.00 118.21 ? 747 THR A O   1 
ATOM   5614 C CB  . THR A 1 746 ? 130.273 158.109 114.298 1.00 124.00 ? 747 THR A CB  1 
ATOM   5615 O OG1 . THR A 1 746 ? 129.177 159.021 114.448 1.00 123.18 ? 747 THR A OG1 1 
ATOM   5616 C CG2 . THR A 1 746 ? 131.074 158.462 113.056 1.00 125.16 ? 747 THR A CG2 1 
ATOM   5617 N N   . GLN A 1 747 ? 127.499 156.890 113.348 1.00 118.68 ? 748 GLN A N   1 
ATOM   5618 C CA  . GLN A 1 747 ? 126.417 156.640 112.406 1.00 121.36 ? 748 GLN A CA  1 
ATOM   5619 C C   . GLN A 1 747 ? 126.164 157.900 111.589 1.00 126.86 ? 748 GLN A C   1 
ATOM   5620 O O   . GLN A 1 747 ? 126.072 158.999 112.144 1.00 130.29 ? 748 GLN A O   1 
ATOM   5621 C CB  . GLN A 1 747 ? 125.151 156.208 113.152 1.00 120.64 ? 748 GLN A CB  1 
ATOM   5622 C CG  . GLN A 1 747 ? 124.165 155.345 112.355 1.00 123.41 ? 748 GLN A CG  1 
ATOM   5623 C CD  . GLN A 1 747 ? 123.448 156.080 111.242 1.00 128.61 ? 748 GLN A CD  1 
ATOM   5624 O OE1 . GLN A 1 747 ? 123.136 157.264 111.362 1.00 127.04 ? 748 GLN A OE1 1 
ATOM   5625 N NE2 . GLN A 1 747 ? 123.180 155.378 110.148 1.00 134.74 ? 748 GLN A NE2 1 
ATOM   5626 N N   . VAL A 1 748 ? 126.052 157.735 110.273 1.00 126.73 ? 749 VAL A N   1 
ATOM   5627 C CA  . VAL A 1 748 ? 125.703 158.809 109.356 1.00 130.58 ? 749 VAL A CA  1 
ATOM   5628 C C   . VAL A 1 748 ? 124.425 158.400 108.640 1.00 130.67 ? 749 VAL A C   1 
ATOM   5629 O O   . VAL A 1 748 ? 124.378 157.340 108.001 1.00 135.81 ? 749 VAL A O   1 
ATOM   5630 C CB  . VAL A 1 748 ? 126.837 159.090 108.352 1.00 128.24 ? 749 VAL A CB  1 
ATOM   5631 C CG1 . VAL A 1 748 ? 126.329 159.895 107.161 1.00 126.68 ? 749 VAL A CG1 1 
ATOM   5632 C CG2 . VAL A 1 748 ? 127.988 159.808 109.036 1.00 132.51 ? 749 VAL A CG2 1 
ATOM   5633 N N   . THR A 1 749 ? 123.391 159.230 108.760 1.00 129.91 ? 750 THR A N   1 
ATOM   5634 C CA  . THR A 1 749 ? 122.098 158.986 108.136 1.00 135.54 ? 750 THR A CA  1 
ATOM   5635 C C   . THR A 1 749 ? 121.835 160.072 107.105 1.00 137.16 ? 750 THR A C   1 
ATOM   5636 O O   . THR A 1 749 ? 121.937 161.263 107.414 1.00 139.04 ? 750 THR A O   1 
ATOM   5637 C CB  . THR A 1 749 ? 120.970 158.962 109.175 1.00 142.80 ? 750 THR A CB  1 
ATOM   5638 O OG1 . THR A 1 749 ? 121.224 157.934 110.137 1.00 145.59 ? 750 THR A OG1 1 
ATOM   5639 C CG2 . THR A 1 749 ? 119.631 158.676 108.508 1.00 143.53 ? 750 THR A CG2 1 
ATOM   5640 N N   . VAL A 1 750 ? 121.503 159.660 105.886 1.00 139.64 ? 751 VAL A N   1 
ATOM   5641 C CA  . VAL A 1 750 ? 121.137 160.577 104.814 1.00 147.38 ? 751 VAL A CA  1 
ATOM   5642 C C   . VAL A 1 750 ? 119.659 160.372 104.517 1.00 142.76 ? 751 VAL A C   1 
ATOM   5643 O O   . VAL A 1 750 ? 119.240 159.271 104.138 1.00 136.93 ? 751 VAL A O   1 
ATOM   5644 C CB  . VAL A 1 750 ? 121.996 160.356 103.560 1.00 149.56 ? 751 VAL A CB  1 
ATOM   5645 C CG1 . VAL A 1 750 ? 121.605 161.337 102.473 1.00 150.07 ? 751 VAL A CG1 1 
ATOM   5646 C CG2 . VAL A 1 750 ? 123.474 160.492 103.900 1.00 145.01 ? 751 VAL A CG2 1 
ATOM   5647 N N   . SER A 1 751 ? 118.870 161.425 104.697 1.00 146.12 ? 752 SER A N   1 
ATOM   5648 C CA  . SER A 1 751 ? 117.431 161.355 104.475 1.00 144.59 ? 752 SER A CA  1 
ATOM   5649 C C   . SER A 1 751 ? 116.881 162.701 104.013 1.00 148.72 ? 752 SER A C   1 
ATOM   5650 O O   . SER A 1 751 ? 116.354 163.474 104.813 1.00 143.73 ? 752 SER A O   1 
ATOM   5651 C CB  . SER A 1 751 ? 116.712 160.903 105.747 1.00 146.36 ? 752 SER A CB  1 
ATOM   5652 O OG  . SER A 1 751 ? 117.084 159.585 106.108 1.00 148.92 ? 752 SER A OG  1 
HETATM 5653 N N1  . SPD B 2 .   ? 142.277 142.746 156.764 1.00 127.08 ? 801 SPD A N1  1 
HETATM 5654 C C2  . SPD B 2 .   ? 141.506 141.519 156.693 1.00 128.25 ? 801 SPD A C2  1 
HETATM 5655 C C3  . SPD B 2 .   ? 142.409 140.313 156.936 1.00 132.57 ? 801 SPD A C3  1 
HETATM 5656 C C4  . SPD B 2 .   ? 143.518 140.600 157.946 1.00 137.18 ? 801 SPD A C4  1 
HETATM 5657 C C5  . SPD B 2 .   ? 143.185 140.101 159.350 1.00 139.07 ? 801 SPD A C5  1 
HETATM 5658 N N6  . SPD B 2 .   ? 142.084 140.863 159.910 1.00 136.13 ? 801 SPD A N6  1 
HETATM 5659 C C7  . SPD B 2 .   ? 142.512 142.229 160.150 1.00 133.40 ? 801 SPD A C7  1 
HETATM 5660 C C8  . SPD B 2 .   ? 141.889 142.767 161.436 1.00 132.53 ? 801 SPD A C8  1 
HETATM 5661 C C9  . SPD B 2 .   ? 142.722 142.430 162.668 1.00 137.25 ? 801 SPD A C9  1 
HETATM 5662 N N10 . SPD B 2 .   ? 142.299 143.234 163.799 1.00 138.09 ? 801 SPD A N10 1 
HETATM 5663 O O   . HOH C 3 .   ? 139.418 144.221 168.161 1.00 123.08 ? 901 HOH A O   1 
# 
